data_8XND
# 
_entry.id   8XND 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8XND         pdb_00008xnd 10.2210/pdb8xnd/pdb 
WWPDB D_1300043860 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-02 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8XND 
_pdbx_database_status.recvd_initial_deposition_date   2023-12-29 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhaoyongy@imb.pumc.edu.cn 
_pdbx_contact_author.name_first         Zhaoyong 
_pdbx_contact_author.name_last          Yang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1497-3781 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Fan, S.'  1 ? 
'Wei, X.'  2 ? 
'Lv, R.'   3 ? 
'Wang, C.' 4 ? 
'Tang, M.' 5 ? 
'Jin, Y.'  6 ? 
'Yang, Z.' 7 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Crystal structure of serine hydroxymethyltransferase 1' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Fan, S.'  1 ? 
primary 'Wei, X.'  2 ? 
primary 'Lv, R.'   3 ? 
primary 'Wang, C.' 4 ? 
primary 'Tang, M.' 5 ? 
primary 'Jin, Y.'  6 ? 
primary 'Yang, Z.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Serine hydroxymethyltransferase, cytosolic' 51706.715 4 2.1.2.1 ? ? ? 
2 non-polymer syn "PYRIDOXAL-5'-PHOSPHATE"                     247.142   4 ?       ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'SHMT,Glycine hydroxymethyltransferase,Serine methylase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;QGDADLWSSHDAMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEF
IDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFE
SMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHC
HVVTTTTHKTLRGCRAGMIFYRKGVKSVDPATGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQ
HQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPAL
TSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVAATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;QGDADLWSSHDAMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEF
IDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFE
SMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHC
HVVTTTTHKTLRGCRAGMIFYRKGVKSVDPATGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQ
HQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPAL
TSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVAATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        "PYRIDOXAL-5'-PHOSPHATE" 
_pdbx_entity_nonpoly.comp_id     PLP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLN n 
1 2   GLY n 
1 3   ASP n 
1 4   ALA n 
1 5   ASP n 
1 6   LEU n 
1 7   TRP n 
1 8   SER n 
1 9   SER n 
1 10  HIS n 
1 11  ASP n 
1 12  ALA n 
1 13  MET n 
1 14  LEU n 
1 15  ALA n 
1 16  GLN n 
1 17  PRO n 
1 18  LEU n 
1 19  LYS n 
1 20  ASP n 
1 21  SER n 
1 22  ASP n 
1 23  VAL n 
1 24  GLU n 
1 25  VAL n 
1 26  TYR n 
1 27  ASN n 
1 28  ILE n 
1 29  ILE n 
1 30  LYS n 
1 31  LYS n 
1 32  GLU n 
1 33  SER n 
1 34  ASN n 
1 35  ARG n 
1 36  GLN n 
1 37  ARG n 
1 38  VAL n 
1 39  GLY n 
1 40  LEU n 
1 41  GLU n 
1 42  LEU n 
1 43  ILE n 
1 44  ALA n 
1 45  SER n 
1 46  GLU n 
1 47  ASN n 
1 48  PHE n 
1 49  ALA n 
1 50  SER n 
1 51  ARG n 
1 52  ALA n 
1 53  VAL n 
1 54  LEU n 
1 55  GLU n 
1 56  ALA n 
1 57  LEU n 
1 58  GLY n 
1 59  SER n 
1 60  CYS n 
1 61  LEU n 
1 62  ASN n 
1 63  ASN n 
1 64  LYS n 
1 65  TYR n 
1 66  SER n 
1 67  GLU n 
1 68  GLY n 
1 69  TYR n 
1 70  PRO n 
1 71  GLY n 
1 72  GLN n 
1 73  ARG n 
1 74  TYR n 
1 75  TYR n 
1 76  GLY n 
1 77  GLY n 
1 78  THR n 
1 79  GLU n 
1 80  PHE n 
1 81  ILE n 
1 82  ASP n 
1 83  GLU n 
1 84  LEU n 
1 85  GLU n 
1 86  THR n 
1 87  LEU n 
1 88  CYS n 
1 89  GLN n 
1 90  LYS n 
1 91  ARG n 
1 92  ALA n 
1 93  LEU n 
1 94  GLN n 
1 95  ALA n 
1 96  TYR n 
1 97  LYS n 
1 98  LEU n 
1 99  ASP n 
1 100 PRO n 
1 101 GLN n 
1 102 CYS n 
1 103 TRP n 
1 104 GLY n 
1 105 VAL n 
1 106 ASN n 
1 107 VAL n 
1 108 GLN n 
1 109 PRO n 
1 110 TYR n 
1 111 SER n 
1 112 GLY n 
1 113 SER n 
1 114 PRO n 
1 115 ALA n 
1 116 ASN n 
1 117 PHE n 
1 118 ALA n 
1 119 VAL n 
1 120 TYR n 
1 121 THR n 
1 122 ALA n 
1 123 LEU n 
1 124 VAL n 
1 125 GLU n 
1 126 PRO n 
1 127 HIS n 
1 128 GLY n 
1 129 ARG n 
1 130 ILE n 
1 131 MET n 
1 132 GLY n 
1 133 LEU n 
1 134 ASP n 
1 135 LEU n 
1 136 PRO n 
1 137 ASP n 
1 138 GLY n 
1 139 GLY n 
1 140 HIS n 
1 141 LEU n 
1 142 THR n 
1 143 HIS n 
1 144 GLY n 
1 145 PHE n 
1 146 MET n 
1 147 THR n 
1 148 ASP n 
1 149 LYS n 
1 150 LYS n 
1 151 LYS n 
1 152 ILE n 
1 153 SER n 
1 154 ALA n 
1 155 THR n 
1 156 SER n 
1 157 ILE n 
1 158 PHE n 
1 159 PHE n 
1 160 GLU n 
1 161 SER n 
1 162 MET n 
1 163 PRO n 
1 164 TYR n 
1 165 LYS n 
1 166 VAL n 
1 167 ASN n 
1 168 PRO n 
1 169 ASP n 
1 170 THR n 
1 171 GLY n 
1 172 TYR n 
1 173 ILE n 
1 174 ASN n 
1 175 TYR n 
1 176 ASP n 
1 177 GLN n 
1 178 LEU n 
1 179 GLU n 
1 180 GLU n 
1 181 ASN n 
1 182 ALA n 
1 183 ARG n 
1 184 LEU n 
1 185 PHE n 
1 186 HIS n 
1 187 PRO n 
1 188 LYS n 
1 189 LEU n 
1 190 ILE n 
1 191 ILE n 
1 192 ALA n 
1 193 GLY n 
1 194 THR n 
1 195 SER n 
1 196 CYS n 
1 197 TYR n 
1 198 SER n 
1 199 ARG n 
1 200 ASN n 
1 201 LEU n 
1 202 GLU n 
1 203 TYR n 
1 204 ALA n 
1 205 ARG n 
1 206 LEU n 
1 207 ARG n 
1 208 LYS n 
1 209 ILE n 
1 210 ALA n 
1 211 ASP n 
1 212 GLU n 
1 213 ASN n 
1 214 GLY n 
1 215 ALA n 
1 216 TYR n 
1 217 LEU n 
1 218 MET n 
1 219 ALA n 
1 220 ASP n 
1 221 MET n 
1 222 ALA n 
1 223 HIS n 
1 224 ILE n 
1 225 SER n 
1 226 GLY n 
1 227 LEU n 
1 228 VAL n 
1 229 ALA n 
1 230 ALA n 
1 231 GLY n 
1 232 VAL n 
1 233 VAL n 
1 234 PRO n 
1 235 SER n 
1 236 PRO n 
1 237 PHE n 
1 238 GLU n 
1 239 HIS n 
1 240 CYS n 
1 241 HIS n 
1 242 VAL n 
1 243 VAL n 
1 244 THR n 
1 245 THR n 
1 246 THR n 
1 247 THR n 
1 248 HIS n 
1 249 LYS n 
1 250 THR n 
1 251 LEU n 
1 252 ARG n 
1 253 GLY n 
1 254 CYS n 
1 255 ARG n 
1 256 ALA n 
1 257 GLY n 
1 258 MET n 
1 259 ILE n 
1 260 PHE n 
1 261 TYR n 
1 262 ARG n 
1 263 LYS n 
1 264 GLY n 
1 265 VAL n 
1 266 LYS n 
1 267 SER n 
1 268 VAL n 
1 269 ASP n 
1 270 PRO n 
1 271 ALA n 
1 272 THR n 
1 273 GLY n 
1 274 LYS n 
1 275 GLU n 
1 276 ILE n 
1 277 LEU n 
1 278 TYR n 
1 279 ASN n 
1 280 LEU n 
1 281 GLU n 
1 282 SER n 
1 283 LEU n 
1 284 ILE n 
1 285 ASN n 
1 286 SER n 
1 287 ALA n 
1 288 VAL n 
1 289 PHE n 
1 290 PRO n 
1 291 GLY n 
1 292 LEU n 
1 293 GLN n 
1 294 GLY n 
1 295 GLY n 
1 296 PRO n 
1 297 HIS n 
1 298 ASN n 
1 299 HIS n 
1 300 ALA n 
1 301 ILE n 
1 302 ALA n 
1 303 GLY n 
1 304 VAL n 
1 305 ALA n 
1 306 VAL n 
1 307 ALA n 
1 308 LEU n 
1 309 LYS n 
1 310 GLN n 
1 311 ALA n 
1 312 MET n 
1 313 THR n 
1 314 LEU n 
1 315 GLU n 
1 316 PHE n 
1 317 LYS n 
1 318 VAL n 
1 319 TYR n 
1 320 GLN n 
1 321 HIS n 
1 322 GLN n 
1 323 VAL n 
1 324 VAL n 
1 325 ALA n 
1 326 ASN n 
1 327 CYS n 
1 328 ARG n 
1 329 ALA n 
1 330 LEU n 
1 331 SER n 
1 332 GLU n 
1 333 ALA n 
1 334 LEU n 
1 335 THR n 
1 336 GLU n 
1 337 LEU n 
1 338 GLY n 
1 339 TYR n 
1 340 LYS n 
1 341 ILE n 
1 342 VAL n 
1 343 THR n 
1 344 GLY n 
1 345 GLY n 
1 346 SER n 
1 347 ASP n 
1 348 ASN n 
1 349 HIS n 
1 350 LEU n 
1 351 ILE n 
1 352 LEU n 
1 353 VAL n 
1 354 ASP n 
1 355 LEU n 
1 356 ARG n 
1 357 SER n 
1 358 LYS n 
1 359 GLY n 
1 360 THR n 
1 361 ASP n 
1 362 GLY n 
1 363 GLY n 
1 364 ARG n 
1 365 ALA n 
1 366 GLU n 
1 367 LYS n 
1 368 VAL n 
1 369 LEU n 
1 370 GLU n 
1 371 ALA n 
1 372 CYS n 
1 373 SER n 
1 374 ILE n 
1 375 ALA n 
1 376 CYS n 
1 377 ASN n 
1 378 LYS n 
1 379 ASN n 
1 380 THR n 
1 381 CYS n 
1 382 PRO n 
1 383 GLY n 
1 384 ASP n 
1 385 ARG n 
1 386 SER n 
1 387 ALA n 
1 388 LEU n 
1 389 ARG n 
1 390 PRO n 
1 391 SER n 
1 392 GLY n 
1 393 LEU n 
1 394 ARG n 
1 395 LEU n 
1 396 GLY n 
1 397 THR n 
1 398 PRO n 
1 399 ALA n 
1 400 LEU n 
1 401 THR n 
1 402 SER n 
1 403 ARG n 
1 404 GLY n 
1 405 LEU n 
1 406 LEU n 
1 407 GLU n 
1 408 LYS n 
1 409 ASP n 
1 410 PHE n 
1 411 GLN n 
1 412 LYS n 
1 413 VAL n 
1 414 ALA n 
1 415 HIS n 
1 416 PHE n 
1 417 ILE n 
1 418 HIS n 
1 419 ARG n 
1 420 GLY n 
1 421 ILE n 
1 422 GLU n 
1 423 LEU n 
1 424 THR n 
1 425 LEU n 
1 426 GLN n 
1 427 ILE n 
1 428 GLN n 
1 429 SER n 
1 430 ASP n 
1 431 THR n 
1 432 GLY n 
1 433 VAL n 
1 434 ALA n 
1 435 ALA n 
1 436 THR n 
1 437 LEU n 
1 438 LYS n 
1 439 GLU n 
1 440 PHE n 
1 441 LYS n 
1 442 GLU n 
1 443 ARG n 
1 444 LEU n 
1 445 ALA n 
1 446 GLY n 
1 447 ASP n 
1 448 LYS n 
1 449 TYR n 
1 450 GLN n 
1 451 ALA n 
1 452 ALA n 
1 453 VAL n 
1 454 GLN n 
1 455 ALA n 
1 456 LEU n 
1 457 ARG n 
1 458 GLU n 
1 459 GLU n 
1 460 VAL n 
1 461 GLU n 
1 462 SER n 
1 463 PHE n 
1 464 ALA n 
1 465 SER n 
1 466 LEU n 
1 467 PHE n 
1 468 PRO n 
1 469 LEU n 
1 470 PRO n 
1 471 GLY n 
1 472 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   472 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 SHMT1 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                  ?                      'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                 ?                      'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE               ?                      'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'          ?                      'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                 ?                      'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                ?                      'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'          ?                      'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                  ?                      'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                ?                      'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE               ?                      'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                  ?                      'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                   ?                      'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE               ?                      'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE            ?                      'C9 H11 N O2'    165.189 
PLP non-polymer         . "PYRIDOXAL-5'-PHOSPHATE" 'VITAMIN B6 Phosphate' 'C8 H10 N O6 P'  247.142 
PRO 'L-peptide linking' y PROLINE                  ?                      'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                   ?                      'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                ?                      'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN               ?                      'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                 ?                      'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                   ?                      'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLN 1   9   9   GLN GLN A . n 
A 1 2   GLY 2   10  10  GLY GLY A . n 
A 1 3   ASP 3   11  11  ASP ASP A . n 
A 1 4   ALA 4   12  12  ALA ALA A . n 
A 1 5   ASP 5   13  13  ASP ASP A . n 
A 1 6   LEU 6   14  14  LEU LEU A . n 
A 1 7   TRP 7   15  15  TRP TRP A . n 
A 1 8   SER 8   16  16  SER SER A . n 
A 1 9   SER 9   17  17  SER SER A . n 
A 1 10  HIS 10  18  18  HIS HIS A . n 
A 1 11  ASP 11  19  19  ASP ASP A . n 
A 1 12  ALA 12  20  20  ALA ALA A . n 
A 1 13  MET 13  21  21  MET MET A . n 
A 1 14  LEU 14  22  22  LEU LEU A . n 
A 1 15  ALA 15  23  23  ALA ALA A . n 
A 1 16  GLN 16  24  24  GLN GLN A . n 
A 1 17  PRO 17  25  25  PRO PRO A . n 
A 1 18  LEU 18  26  26  LEU LEU A . n 
A 1 19  LYS 19  27  27  LYS LYS A . n 
A 1 20  ASP 20  28  28  ASP ASP A . n 
A 1 21  SER 21  29  29  SER SER A . n 
A 1 22  ASP 22  30  30  ASP ASP A . n 
A 1 23  VAL 23  31  31  VAL VAL A . n 
A 1 24  GLU 24  32  32  GLU GLU A . n 
A 1 25  VAL 25  33  33  VAL VAL A . n 
A 1 26  TYR 26  34  34  TYR TYR A . n 
A 1 27  ASN 27  35  35  ASN ASN A . n 
A 1 28  ILE 28  36  36  ILE ILE A . n 
A 1 29  ILE 29  37  37  ILE ILE A . n 
A 1 30  LYS 30  38  38  LYS LYS A . n 
A 1 31  LYS 31  39  39  LYS LYS A . n 
A 1 32  GLU 32  40  40  GLU GLU A . n 
A 1 33  SER 33  41  41  SER SER A . n 
A 1 34  ASN 34  42  42  ASN ASN A . n 
A 1 35  ARG 35  43  43  ARG ARG A . n 
A 1 36  GLN 36  44  44  GLN GLN A . n 
A 1 37  ARG 37  45  45  ARG ARG A . n 
A 1 38  VAL 38  46  46  VAL VAL A . n 
A 1 39  GLY 39  47  47  GLY GLY A . n 
A 1 40  LEU 40  48  48  LEU LEU A . n 
A 1 41  GLU 41  49  49  GLU GLU A . n 
A 1 42  LEU 42  50  50  LEU LEU A . n 
A 1 43  ILE 43  51  51  ILE ILE A . n 
A 1 44  ALA 44  52  52  ALA ALA A . n 
A 1 45  SER 45  53  53  SER SER A . n 
A 1 46  GLU 46  54  54  GLU GLU A . n 
A 1 47  ASN 47  55  55  ASN ASN A . n 
A 1 48  PHE 48  56  56  PHE PHE A . n 
A 1 49  ALA 49  57  57  ALA ALA A . n 
A 1 50  SER 50  58  58  SER SER A . n 
A 1 51  ARG 51  59  59  ARG ARG A . n 
A 1 52  ALA 52  60  60  ALA ALA A . n 
A 1 53  VAL 53  61  61  VAL VAL A . n 
A 1 54  LEU 54  62  62  LEU LEU A . n 
A 1 55  GLU 55  63  63  GLU GLU A . n 
A 1 56  ALA 56  64  64  ALA ALA A . n 
A 1 57  LEU 57  65  65  LEU LEU A . n 
A 1 58  GLY 58  66  66  GLY GLY A . n 
A 1 59  SER 59  67  67  SER SER A . n 
A 1 60  CYS 60  68  68  CYS CYS A . n 
A 1 61  LEU 61  69  69  LEU LEU A . n 
A 1 62  ASN 62  70  70  ASN ASN A . n 
A 1 63  ASN 63  71  71  ASN ASN A . n 
A 1 64  LYS 64  72  72  LYS LYS A . n 
A 1 65  TYR 65  73  73  TYR TYR A . n 
A 1 66  SER 66  74  74  SER SER A . n 
A 1 67  GLU 67  75  75  GLU GLU A . n 
A 1 68  GLY 68  76  76  GLY GLY A . n 
A 1 69  TYR 69  77  77  TYR TYR A . n 
A 1 70  PRO 70  78  78  PRO PRO A . n 
A 1 71  GLY 71  79  79  GLY GLY A . n 
A 1 72  GLN 72  80  80  GLN GLN A . n 
A 1 73  ARG 73  81  81  ARG ARG A . n 
A 1 74  TYR 74  82  82  TYR TYR A . n 
A 1 75  TYR 75  83  83  TYR TYR A . n 
A 1 76  GLY 76  84  84  GLY GLY A . n 
A 1 77  GLY 77  85  85  GLY GLY A . n 
A 1 78  THR 78  86  86  THR THR A . n 
A 1 79  GLU 79  87  87  GLU GLU A . n 
A 1 80  PHE 80  88  88  PHE PHE A . n 
A 1 81  ILE 81  89  89  ILE ILE A . n 
A 1 82  ASP 82  90  90  ASP ASP A . n 
A 1 83  GLU 83  91  91  GLU GLU A . n 
A 1 84  LEU 84  92  92  LEU LEU A . n 
A 1 85  GLU 85  93  93  GLU GLU A . n 
A 1 86  THR 86  94  94  THR THR A . n 
A 1 87  LEU 87  95  95  LEU LEU A . n 
A 1 88  CYS 88  96  96  CYS CYS A . n 
A 1 89  GLN 89  97  97  GLN GLN A . n 
A 1 90  LYS 90  98  98  LYS LYS A . n 
A 1 91  ARG 91  99  99  ARG ARG A . n 
A 1 92  ALA 92  100 100 ALA ALA A . n 
A 1 93  LEU 93  101 101 LEU LEU A . n 
A 1 94  GLN 94  102 102 GLN GLN A . n 
A 1 95  ALA 95  103 103 ALA ALA A . n 
A 1 96  TYR 96  104 104 TYR TYR A . n 
A 1 97  LYS 97  105 105 LYS LYS A . n 
A 1 98  LEU 98  106 106 LEU LEU A . n 
A 1 99  ASP 99  107 107 ASP ASP A . n 
A 1 100 PRO 100 108 108 PRO PRO A . n 
A 1 101 GLN 101 109 109 GLN GLN A . n 
A 1 102 CYS 102 110 110 CYS CYS A . n 
A 1 103 TRP 103 111 111 TRP TRP A . n 
A 1 104 GLY 104 112 112 GLY GLY A . n 
A 1 105 VAL 105 113 113 VAL VAL A . n 
A 1 106 ASN 106 114 114 ASN ASN A . n 
A 1 107 VAL 107 115 115 VAL VAL A . n 
A 1 108 GLN 108 116 116 GLN GLN A . n 
A 1 109 PRO 109 117 117 PRO PRO A . n 
A 1 110 TYR 110 118 118 TYR TYR A . n 
A 1 111 SER 111 119 119 SER SER A . n 
A 1 112 GLY 112 120 120 GLY GLY A . n 
A 1 113 SER 113 121 121 SER SER A . n 
A 1 114 PRO 114 122 122 PRO PRO A . n 
A 1 115 ALA 115 123 123 ALA ALA A . n 
A 1 116 ASN 116 124 124 ASN ASN A . n 
A 1 117 PHE 117 125 125 PHE PHE A . n 
A 1 118 ALA 118 126 126 ALA ALA A . n 
A 1 119 VAL 119 127 127 VAL VAL A . n 
A 1 120 TYR 120 128 128 TYR TYR A . n 
A 1 121 THR 121 129 129 THR THR A . n 
A 1 122 ALA 122 130 130 ALA ALA A . n 
A 1 123 LEU 123 131 131 LEU LEU A . n 
A 1 124 VAL 124 132 132 VAL VAL A . n 
A 1 125 GLU 125 133 133 GLU GLU A . n 
A 1 126 PRO 126 134 134 PRO PRO A . n 
A 1 127 HIS 127 135 135 HIS HIS A . n 
A 1 128 GLY 128 136 136 GLY GLY A . n 
A 1 129 ARG 129 137 137 ARG ARG A . n 
A 1 130 ILE 130 138 138 ILE ILE A . n 
A 1 131 MET 131 139 139 MET MET A . n 
A 1 132 GLY 132 140 140 GLY GLY A . n 
A 1 133 LEU 133 141 141 LEU LEU A . n 
A 1 134 ASP 134 142 142 ASP ASP A . n 
A 1 135 LEU 135 143 143 LEU LEU A . n 
A 1 136 PRO 136 144 144 PRO PRO A . n 
A 1 137 ASP 137 145 145 ASP ASP A . n 
A 1 138 GLY 138 146 146 GLY GLY A . n 
A 1 139 GLY 139 147 147 GLY GLY A . n 
A 1 140 HIS 140 148 148 HIS HIS A . n 
A 1 141 LEU 141 149 149 LEU LEU A . n 
A 1 142 THR 142 150 150 THR THR A . n 
A 1 143 HIS 143 151 151 HIS HIS A . n 
A 1 144 GLY 144 152 152 GLY GLY A . n 
A 1 145 PHE 145 153 153 PHE PHE A . n 
A 1 146 MET 146 154 154 MET MET A . n 
A 1 147 THR 147 155 155 THR THR A . n 
A 1 148 ASP 148 156 156 ASP ASP A . n 
A 1 149 LYS 149 157 157 LYS LYS A . n 
A 1 150 LYS 150 158 158 LYS LYS A . n 
A 1 151 LYS 151 159 159 LYS LYS A . n 
A 1 152 ILE 152 160 160 ILE ILE A . n 
A 1 153 SER 153 161 161 SER SER A . n 
A 1 154 ALA 154 162 162 ALA ALA A . n 
A 1 155 THR 155 163 163 THR THR A . n 
A 1 156 SER 156 164 164 SER SER A . n 
A 1 157 ILE 157 165 165 ILE ILE A . n 
A 1 158 PHE 158 166 166 PHE PHE A . n 
A 1 159 PHE 159 167 167 PHE PHE A . n 
A 1 160 GLU 160 168 168 GLU GLU A . n 
A 1 161 SER 161 169 169 SER SER A . n 
A 1 162 MET 162 170 170 MET MET A . n 
A 1 163 PRO 163 171 171 PRO PRO A . n 
A 1 164 TYR 164 172 172 TYR TYR A . n 
A 1 165 LYS 165 173 173 LYS LYS A . n 
A 1 166 VAL 166 174 174 VAL VAL A . n 
A 1 167 ASN 167 175 175 ASN ASN A . n 
A 1 168 PRO 168 176 176 PRO PRO A . n 
A 1 169 ASP 169 177 177 ASP ASP A . n 
A 1 170 THR 170 178 178 THR THR A . n 
A 1 171 GLY 171 179 179 GLY GLY A . n 
A 1 172 TYR 172 180 180 TYR TYR A . n 
A 1 173 ILE 173 181 181 ILE ILE A . n 
A 1 174 ASN 174 182 182 ASN ASN A . n 
A 1 175 TYR 175 183 183 TYR TYR A . n 
A 1 176 ASP 176 184 184 ASP ASP A . n 
A 1 177 GLN 177 185 185 GLN GLN A . n 
A 1 178 LEU 178 186 186 LEU LEU A . n 
A 1 179 GLU 179 187 187 GLU GLU A . n 
A 1 180 GLU 180 188 188 GLU GLU A . n 
A 1 181 ASN 181 189 189 ASN ASN A . n 
A 1 182 ALA 182 190 190 ALA ALA A . n 
A 1 183 ARG 183 191 191 ARG ARG A . n 
A 1 184 LEU 184 192 192 LEU LEU A . n 
A 1 185 PHE 185 193 193 PHE PHE A . n 
A 1 186 HIS 186 194 194 HIS HIS A . n 
A 1 187 PRO 187 195 195 PRO PRO A . n 
A 1 188 LYS 188 196 196 LYS LYS A . n 
A 1 189 LEU 189 197 197 LEU LEU A . n 
A 1 190 ILE 190 198 198 ILE ILE A . n 
A 1 191 ILE 191 199 199 ILE ILE A . n 
A 1 192 ALA 192 200 200 ALA ALA A . n 
A 1 193 GLY 193 201 201 GLY GLY A . n 
A 1 194 THR 194 202 202 THR THR A . n 
A 1 195 SER 195 203 203 SER SER A . n 
A 1 196 CYS 196 204 204 CYS CYS A . n 
A 1 197 TYR 197 205 205 TYR TYR A . n 
A 1 198 SER 198 206 206 SER SER A . n 
A 1 199 ARG 199 207 207 ARG ARG A . n 
A 1 200 ASN 200 208 208 ASN ASN A . n 
A 1 201 LEU 201 209 209 LEU LEU A . n 
A 1 202 GLU 202 210 210 GLU GLU A . n 
A 1 203 TYR 203 211 211 TYR TYR A . n 
A 1 204 ALA 204 212 212 ALA ALA A . n 
A 1 205 ARG 205 213 213 ARG ARG A . n 
A 1 206 LEU 206 214 214 LEU LEU A . n 
A 1 207 ARG 207 215 215 ARG ARG A . n 
A 1 208 LYS 208 216 216 LYS LYS A . n 
A 1 209 ILE 209 217 217 ILE ILE A . n 
A 1 210 ALA 210 218 218 ALA ALA A . n 
A 1 211 ASP 211 219 219 ASP ASP A . n 
A 1 212 GLU 212 220 220 GLU GLU A . n 
A 1 213 ASN 213 221 221 ASN ASN A . n 
A 1 214 GLY 214 222 222 GLY GLY A . n 
A 1 215 ALA 215 223 223 ALA ALA A . n 
A 1 216 TYR 216 224 224 TYR TYR A . n 
A 1 217 LEU 217 225 225 LEU LEU A . n 
A 1 218 MET 218 226 226 MET MET A . n 
A 1 219 ALA 219 227 227 ALA ALA A . n 
A 1 220 ASP 220 228 228 ASP ASP A . n 
A 1 221 MET 221 229 229 MET MET A . n 
A 1 222 ALA 222 230 230 ALA ALA A . n 
A 1 223 HIS 223 231 231 HIS HIS A . n 
A 1 224 ILE 224 232 232 ILE ILE A . n 
A 1 225 SER 225 233 233 SER SER A . n 
A 1 226 GLY 226 234 234 GLY GLY A . n 
A 1 227 LEU 227 235 235 LEU LEU A . n 
A 1 228 VAL 228 236 236 VAL VAL A . n 
A 1 229 ALA 229 237 237 ALA ALA A . n 
A 1 230 ALA 230 238 238 ALA ALA A . n 
A 1 231 GLY 231 239 239 GLY GLY A . n 
A 1 232 VAL 232 240 240 VAL VAL A . n 
A 1 233 VAL 233 241 241 VAL VAL A . n 
A 1 234 PRO 234 242 242 PRO PRO A . n 
A 1 235 SER 235 243 243 SER SER A . n 
A 1 236 PRO 236 244 244 PRO PRO A . n 
A 1 237 PHE 237 245 245 PHE PHE A . n 
A 1 238 GLU 238 246 246 GLU GLU A . n 
A 1 239 HIS 239 247 247 HIS HIS A . n 
A 1 240 CYS 240 248 248 CYS CYS A . n 
A 1 241 HIS 241 249 249 HIS HIS A . n 
A 1 242 VAL 242 250 250 VAL VAL A . n 
A 1 243 VAL 243 251 251 VAL VAL A . n 
A 1 244 THR 244 252 252 THR THR A . n 
A 1 245 THR 245 253 253 THR THR A . n 
A 1 246 THR 246 254 254 THR THR A . n 
A 1 247 THR 247 255 255 THR THR A . n 
A 1 248 HIS 248 256 256 HIS HIS A . n 
A 1 249 LYS 249 257 257 LYS LYS A . n 
A 1 250 THR 250 258 258 THR THR A . n 
A 1 251 LEU 251 259 259 LEU LEU A . n 
A 1 252 ARG 252 260 260 ARG ARG A . n 
A 1 253 GLY 253 261 261 GLY GLY A . n 
A 1 254 CYS 254 262 262 CYS CYS A . n 
A 1 255 ARG 255 263 263 ARG ARG A . n 
A 1 256 ALA 256 264 264 ALA ALA A . n 
A 1 257 GLY 257 265 265 GLY GLY A . n 
A 1 258 MET 258 266 266 MET MET A . n 
A 1 259 ILE 259 267 267 ILE ILE A . n 
A 1 260 PHE 260 268 268 PHE PHE A . n 
A 1 261 TYR 261 269 269 TYR TYR A . n 
A 1 262 ARG 262 270 270 ARG ARG A . n 
A 1 263 LYS 263 271 271 LYS LYS A . n 
A 1 264 GLY 264 272 272 GLY GLY A . n 
A 1 265 VAL 265 273 273 VAL VAL A . n 
A 1 266 LYS 266 274 274 LYS LYS A . n 
A 1 267 SER 267 275 275 SER SER A . n 
A 1 268 VAL 268 276 276 VAL VAL A . n 
A 1 269 ASP 269 277 277 ASP ASP A . n 
A 1 270 PRO 270 278 278 PRO PRO A . n 
A 1 271 ALA 271 279 279 ALA ALA A . n 
A 1 272 THR 272 280 280 THR THR A . n 
A 1 273 GLY 273 281 281 GLY GLY A . n 
A 1 274 LYS 274 282 282 LYS LYS A . n 
A 1 275 GLU 275 283 283 GLU GLU A . n 
A 1 276 ILE 276 284 284 ILE ILE A . n 
A 1 277 LEU 277 285 285 LEU LEU A . n 
A 1 278 TYR 278 286 286 TYR TYR A . n 
A 1 279 ASN 279 287 287 ASN ASN A . n 
A 1 280 LEU 280 288 288 LEU LEU A . n 
A 1 281 GLU 281 289 289 GLU GLU A . n 
A 1 282 SER 282 290 290 SER SER A . n 
A 1 283 LEU 283 291 291 LEU LEU A . n 
A 1 284 ILE 284 292 292 ILE ILE A . n 
A 1 285 ASN 285 293 293 ASN ASN A . n 
A 1 286 SER 286 294 294 SER SER A . n 
A 1 287 ALA 287 295 295 ALA ALA A . n 
A 1 288 VAL 288 296 296 VAL VAL A . n 
A 1 289 PHE 289 297 297 PHE PHE A . n 
A 1 290 PRO 290 298 298 PRO PRO A . n 
A 1 291 GLY 291 299 299 GLY GLY A . n 
A 1 292 LEU 292 300 300 LEU LEU A . n 
A 1 293 GLN 293 301 301 GLN GLN A . n 
A 1 294 GLY 294 302 302 GLY GLY A . n 
A 1 295 GLY 295 303 303 GLY GLY A . n 
A 1 296 PRO 296 304 304 PRO PRO A . n 
A 1 297 HIS 297 305 305 HIS HIS A . n 
A 1 298 ASN 298 306 306 ASN ASN A . n 
A 1 299 HIS 299 307 307 HIS HIS A . n 
A 1 300 ALA 300 308 308 ALA ALA A . n 
A 1 301 ILE 301 309 309 ILE ILE A . n 
A 1 302 ALA 302 310 310 ALA ALA A . n 
A 1 303 GLY 303 311 311 GLY GLY A . n 
A 1 304 VAL 304 312 312 VAL VAL A . n 
A 1 305 ALA 305 313 313 ALA ALA A . n 
A 1 306 VAL 306 314 314 VAL VAL A . n 
A 1 307 ALA 307 315 315 ALA ALA A . n 
A 1 308 LEU 308 316 316 LEU LEU A . n 
A 1 309 LYS 309 317 317 LYS LYS A . n 
A 1 310 GLN 310 318 318 GLN GLN A . n 
A 1 311 ALA 311 319 319 ALA ALA A . n 
A 1 312 MET 312 320 320 MET MET A . n 
A 1 313 THR 313 321 321 THR THR A . n 
A 1 314 LEU 314 322 322 LEU LEU A . n 
A 1 315 GLU 315 323 323 GLU GLU A . n 
A 1 316 PHE 316 324 324 PHE PHE A . n 
A 1 317 LYS 317 325 325 LYS LYS A . n 
A 1 318 VAL 318 326 326 VAL VAL A . n 
A 1 319 TYR 319 327 327 TYR TYR A . n 
A 1 320 GLN 320 328 328 GLN GLN A . n 
A 1 321 HIS 321 329 329 HIS HIS A . n 
A 1 322 GLN 322 330 330 GLN GLN A . n 
A 1 323 VAL 323 331 331 VAL VAL A . n 
A 1 324 VAL 324 332 332 VAL VAL A . n 
A 1 325 ALA 325 333 333 ALA ALA A . n 
A 1 326 ASN 326 334 334 ASN ASN A . n 
A 1 327 CYS 327 335 335 CYS CYS A . n 
A 1 328 ARG 328 336 336 ARG ARG A . n 
A 1 329 ALA 329 337 337 ALA ALA A . n 
A 1 330 LEU 330 338 338 LEU LEU A . n 
A 1 331 SER 331 339 339 SER SER A . n 
A 1 332 GLU 332 340 340 GLU GLU A . n 
A 1 333 ALA 333 341 341 ALA ALA A . n 
A 1 334 LEU 334 342 342 LEU LEU A . n 
A 1 335 THR 335 343 343 THR THR A . n 
A 1 336 GLU 336 344 344 GLU GLU A . n 
A 1 337 LEU 337 345 345 LEU LEU A . n 
A 1 338 GLY 338 346 346 GLY GLY A . n 
A 1 339 TYR 339 347 347 TYR TYR A . n 
A 1 340 LYS 340 348 348 LYS LYS A . n 
A 1 341 ILE 341 349 349 ILE ILE A . n 
A 1 342 VAL 342 350 350 VAL VAL A . n 
A 1 343 THR 343 351 351 THR THR A . n 
A 1 344 GLY 344 352 352 GLY GLY A . n 
A 1 345 GLY 345 353 353 GLY GLY A . n 
A 1 346 SER 346 354 354 SER SER A . n 
A 1 347 ASP 347 355 355 ASP ASP A . n 
A 1 348 ASN 348 356 356 ASN ASN A . n 
A 1 349 HIS 349 357 357 HIS HIS A . n 
A 1 350 LEU 350 358 358 LEU LEU A . n 
A 1 351 ILE 351 359 359 ILE ILE A . n 
A 1 352 LEU 352 360 360 LEU LEU A . n 
A 1 353 VAL 353 361 361 VAL VAL A . n 
A 1 354 ASP 354 362 362 ASP ASP A . n 
A 1 355 LEU 355 363 363 LEU LEU A . n 
A 1 356 ARG 356 364 364 ARG ARG A . n 
A 1 357 SER 357 365 365 SER SER A . n 
A 1 358 LYS 358 366 366 LYS LYS A . n 
A 1 359 GLY 359 367 367 GLY GLY A . n 
A 1 360 THR 360 368 368 THR THR A . n 
A 1 361 ASP 361 369 369 ASP ASP A . n 
A 1 362 GLY 362 370 370 GLY GLY A . n 
A 1 363 GLY 363 371 371 GLY GLY A . n 
A 1 364 ARG 364 372 372 ARG ARG A . n 
A 1 365 ALA 365 373 373 ALA ALA A . n 
A 1 366 GLU 366 374 374 GLU GLU A . n 
A 1 367 LYS 367 375 375 LYS LYS A . n 
A 1 368 VAL 368 376 376 VAL VAL A . n 
A 1 369 LEU 369 377 377 LEU LEU A . n 
A 1 370 GLU 370 378 378 GLU GLU A . n 
A 1 371 ALA 371 379 379 ALA ALA A . n 
A 1 372 CYS 372 380 380 CYS CYS A . n 
A 1 373 SER 373 381 381 SER SER A . n 
A 1 374 ILE 374 382 382 ILE ILE A . n 
A 1 375 ALA 375 383 383 ALA ALA A . n 
A 1 376 CYS 376 384 384 CYS CYS A . n 
A 1 377 ASN 377 385 385 ASN ASN A . n 
A 1 378 LYS 378 386 386 LYS LYS A . n 
A 1 379 ASN 379 387 387 ASN ASN A . n 
A 1 380 THR 380 388 388 THR THR A . n 
A 1 381 CYS 381 389 389 CYS CYS A . n 
A 1 382 PRO 382 390 390 PRO PRO A . n 
A 1 383 GLY 383 391 391 GLY GLY A . n 
A 1 384 ASP 384 392 392 ASP ASP A . n 
A 1 385 ARG 385 393 393 ARG ARG A . n 
A 1 386 SER 386 394 394 SER SER A . n 
A 1 387 ALA 387 395 395 ALA ALA A . n 
A 1 388 LEU 388 396 396 LEU LEU A . n 
A 1 389 ARG 389 397 397 ARG ARG A . n 
A 1 390 PRO 390 398 398 PRO PRO A . n 
A 1 391 SER 391 399 399 SER SER A . n 
A 1 392 GLY 392 400 400 GLY GLY A . n 
A 1 393 LEU 393 401 401 LEU LEU A . n 
A 1 394 ARG 394 402 402 ARG ARG A . n 
A 1 395 LEU 395 403 403 LEU LEU A . n 
A 1 396 GLY 396 404 404 GLY GLY A . n 
A 1 397 THR 397 405 405 THR THR A . n 
A 1 398 PRO 398 406 406 PRO PRO A . n 
A 1 399 ALA 399 407 407 ALA ALA A . n 
A 1 400 LEU 400 408 408 LEU LEU A . n 
A 1 401 THR 401 409 409 THR THR A . n 
A 1 402 SER 402 410 410 SER SER A . n 
A 1 403 ARG 403 411 411 ARG ARG A . n 
A 1 404 GLY 404 412 412 GLY GLY A . n 
A 1 405 LEU 405 413 413 LEU LEU A . n 
A 1 406 LEU 406 414 414 LEU LEU A . n 
A 1 407 GLU 407 415 415 GLU GLU A . n 
A 1 408 LYS 408 416 416 LYS LYS A . n 
A 1 409 ASP 409 417 417 ASP ASP A . n 
A 1 410 PHE 410 418 418 PHE PHE A . n 
A 1 411 GLN 411 419 419 GLN GLN A . n 
A 1 412 LYS 412 420 420 LYS LYS A . n 
A 1 413 VAL 413 421 421 VAL VAL A . n 
A 1 414 ALA 414 422 422 ALA ALA A . n 
A 1 415 HIS 415 423 423 HIS HIS A . n 
A 1 416 PHE 416 424 424 PHE PHE A . n 
A 1 417 ILE 417 425 425 ILE ILE A . n 
A 1 418 HIS 418 426 426 HIS HIS A . n 
A 1 419 ARG 419 427 427 ARG ARG A . n 
A 1 420 GLY 420 428 428 GLY GLY A . n 
A 1 421 ILE 421 429 429 ILE ILE A . n 
A 1 422 GLU 422 430 430 GLU GLU A . n 
A 1 423 LEU 423 431 431 LEU LEU A . n 
A 1 424 THR 424 432 432 THR THR A . n 
A 1 425 LEU 425 433 433 LEU LEU A . n 
A 1 426 GLN 426 434 434 GLN GLN A . n 
A 1 427 ILE 427 435 435 ILE ILE A . n 
A 1 428 GLN 428 436 436 GLN GLN A . n 
A 1 429 SER 429 437 437 SER SER A . n 
A 1 430 ASP 430 438 438 ASP ASP A . n 
A 1 431 THR 431 439 439 THR THR A . n 
A 1 432 GLY 432 440 440 GLY GLY A . n 
A 1 433 VAL 433 441 441 VAL VAL A . n 
A 1 434 ALA 434 442 442 ALA ALA A . n 
A 1 435 ALA 435 443 443 ALA ALA A . n 
A 1 436 THR 436 444 444 THR THR A . n 
A 1 437 LEU 437 445 445 LEU LEU A . n 
A 1 438 LYS 438 446 446 LYS LYS A . n 
A 1 439 GLU 439 447 447 GLU GLU A . n 
A 1 440 PHE 440 448 448 PHE PHE A . n 
A 1 441 LYS 441 449 449 LYS LYS A . n 
A 1 442 GLU 442 450 450 GLU GLU A . n 
A 1 443 ARG 443 451 451 ARG ARG A . n 
A 1 444 LEU 444 452 452 LEU LEU A . n 
A 1 445 ALA 445 453 453 ALA ALA A . n 
A 1 446 GLY 446 454 454 GLY GLY A . n 
A 1 447 ASP 447 455 455 ASP ASP A . n 
A 1 448 LYS 448 456 456 LYS LYS A . n 
A 1 449 TYR 449 457 457 TYR TYR A . n 
A 1 450 GLN 450 458 458 GLN GLN A . n 
A 1 451 ALA 451 459 459 ALA ALA A . n 
A 1 452 ALA 452 460 460 ALA ALA A . n 
A 1 453 VAL 453 461 461 VAL VAL A . n 
A 1 454 GLN 454 462 462 GLN GLN A . n 
A 1 455 ALA 455 463 463 ALA ALA A . n 
A 1 456 LEU 456 464 464 LEU LEU A . n 
A 1 457 ARG 457 465 465 ARG ARG A . n 
A 1 458 GLU 458 466 466 GLU GLU A . n 
A 1 459 GLU 459 467 467 GLU GLU A . n 
A 1 460 VAL 460 468 468 VAL VAL A . n 
A 1 461 GLU 461 469 469 GLU GLU A . n 
A 1 462 SER 462 470 470 SER SER A . n 
A 1 463 PHE 463 471 471 PHE PHE A . n 
A 1 464 ALA 464 472 472 ALA ALA A . n 
A 1 465 SER 465 473 473 SER SER A . n 
A 1 466 LEU 466 474 474 LEU LEU A . n 
A 1 467 PHE 467 475 475 PHE PHE A . n 
A 1 468 PRO 468 476 476 PRO PRO A . n 
A 1 469 LEU 469 477 477 LEU LEU A . n 
A 1 470 PRO 470 478 478 PRO PRO A . n 
A 1 471 GLY 471 479 479 GLY GLY A . n 
A 1 472 LEU 472 480 480 LEU LEU A . n 
B 1 1   GLN 1   9   9   GLN GLN B . n 
B 1 2   GLY 2   10  10  GLY GLY B . n 
B 1 3   ASP 3   11  11  ASP ASP B . n 
B 1 4   ALA 4   12  12  ALA ALA B . n 
B 1 5   ASP 5   13  13  ASP ASP B . n 
B 1 6   LEU 6   14  14  LEU LEU B . n 
B 1 7   TRP 7   15  15  TRP TRP B . n 
B 1 8   SER 8   16  16  SER SER B . n 
B 1 9   SER 9   17  17  SER SER B . n 
B 1 10  HIS 10  18  18  HIS HIS B . n 
B 1 11  ASP 11  19  19  ASP ASP B . n 
B 1 12  ALA 12  20  20  ALA ALA B . n 
B 1 13  MET 13  21  21  MET MET B . n 
B 1 14  LEU 14  22  22  LEU LEU B . n 
B 1 15  ALA 15  23  23  ALA ALA B . n 
B 1 16  GLN 16  24  24  GLN GLN B . n 
B 1 17  PRO 17  25  25  PRO PRO B . n 
B 1 18  LEU 18  26  26  LEU LEU B . n 
B 1 19  LYS 19  27  27  LYS LYS B . n 
B 1 20  ASP 20  28  28  ASP ASP B . n 
B 1 21  SER 21  29  29  SER SER B . n 
B 1 22  ASP 22  30  30  ASP ASP B . n 
B 1 23  VAL 23  31  31  VAL VAL B . n 
B 1 24  GLU 24  32  32  GLU GLU B . n 
B 1 25  VAL 25  33  33  VAL VAL B . n 
B 1 26  TYR 26  34  34  TYR TYR B . n 
B 1 27  ASN 27  35  35  ASN ASN B . n 
B 1 28  ILE 28  36  36  ILE ILE B . n 
B 1 29  ILE 29  37  37  ILE ILE B . n 
B 1 30  LYS 30  38  38  LYS LYS B . n 
B 1 31  LYS 31  39  39  LYS LYS B . n 
B 1 32  GLU 32  40  40  GLU GLU B . n 
B 1 33  SER 33  41  41  SER SER B . n 
B 1 34  ASN 34  42  42  ASN ASN B . n 
B 1 35  ARG 35  43  43  ARG ARG B . n 
B 1 36  GLN 36  44  44  GLN GLN B . n 
B 1 37  ARG 37  45  45  ARG ARG B . n 
B 1 38  VAL 38  46  46  VAL VAL B . n 
B 1 39  GLY 39  47  47  GLY GLY B . n 
B 1 40  LEU 40  48  48  LEU LEU B . n 
B 1 41  GLU 41  49  49  GLU GLU B . n 
B 1 42  LEU 42  50  50  LEU LEU B . n 
B 1 43  ILE 43  51  51  ILE ILE B . n 
B 1 44  ALA 44  52  52  ALA ALA B . n 
B 1 45  SER 45  53  53  SER SER B . n 
B 1 46  GLU 46  54  54  GLU GLU B . n 
B 1 47  ASN 47  55  55  ASN ASN B . n 
B 1 48  PHE 48  56  56  PHE PHE B . n 
B 1 49  ALA 49  57  57  ALA ALA B . n 
B 1 50  SER 50  58  58  SER SER B . n 
B 1 51  ARG 51  59  59  ARG ARG B . n 
B 1 52  ALA 52  60  60  ALA ALA B . n 
B 1 53  VAL 53  61  61  VAL VAL B . n 
B 1 54  LEU 54  62  62  LEU LEU B . n 
B 1 55  GLU 55  63  63  GLU GLU B . n 
B 1 56  ALA 56  64  64  ALA ALA B . n 
B 1 57  LEU 57  65  65  LEU LEU B . n 
B 1 58  GLY 58  66  66  GLY GLY B . n 
B 1 59  SER 59  67  67  SER SER B . n 
B 1 60  CYS 60  68  68  CYS CYS B . n 
B 1 61  LEU 61  69  69  LEU LEU B . n 
B 1 62  ASN 62  70  70  ASN ASN B . n 
B 1 63  ASN 63  71  71  ASN ASN B . n 
B 1 64  LYS 64  72  72  LYS LYS B . n 
B 1 65  TYR 65  73  73  TYR TYR B . n 
B 1 66  SER 66  74  74  SER SER B . n 
B 1 67  GLU 67  75  75  GLU GLU B . n 
B 1 68  GLY 68  76  76  GLY GLY B . n 
B 1 69  TYR 69  77  77  TYR TYR B . n 
B 1 70  PRO 70  78  78  PRO PRO B . n 
B 1 71  GLY 71  79  79  GLY GLY B . n 
B 1 72  GLN 72  80  80  GLN GLN B . n 
B 1 73  ARG 73  81  81  ARG ARG B . n 
B 1 74  TYR 74  82  82  TYR TYR B . n 
B 1 75  TYR 75  83  83  TYR TYR B . n 
B 1 76  GLY 76  84  84  GLY GLY B . n 
B 1 77  GLY 77  85  85  GLY GLY B . n 
B 1 78  THR 78  86  86  THR THR B . n 
B 1 79  GLU 79  87  87  GLU GLU B . n 
B 1 80  PHE 80  88  88  PHE PHE B . n 
B 1 81  ILE 81  89  89  ILE ILE B . n 
B 1 82  ASP 82  90  90  ASP ASP B . n 
B 1 83  GLU 83  91  91  GLU GLU B . n 
B 1 84  LEU 84  92  92  LEU LEU B . n 
B 1 85  GLU 85  93  93  GLU GLU B . n 
B 1 86  THR 86  94  94  THR THR B . n 
B 1 87  LEU 87  95  95  LEU LEU B . n 
B 1 88  CYS 88  96  96  CYS CYS B . n 
B 1 89  GLN 89  97  97  GLN GLN B . n 
B 1 90  LYS 90  98  98  LYS LYS B . n 
B 1 91  ARG 91  99  99  ARG ARG B . n 
B 1 92  ALA 92  100 100 ALA ALA B . n 
B 1 93  LEU 93  101 101 LEU LEU B . n 
B 1 94  GLN 94  102 102 GLN GLN B . n 
B 1 95  ALA 95  103 103 ALA ALA B . n 
B 1 96  TYR 96  104 104 TYR TYR B . n 
B 1 97  LYS 97  105 105 LYS LYS B . n 
B 1 98  LEU 98  106 106 LEU LEU B . n 
B 1 99  ASP 99  107 107 ASP ASP B . n 
B 1 100 PRO 100 108 108 PRO PRO B . n 
B 1 101 GLN 101 109 109 GLN GLN B . n 
B 1 102 CYS 102 110 110 CYS CYS B . n 
B 1 103 TRP 103 111 111 TRP TRP B . n 
B 1 104 GLY 104 112 112 GLY GLY B . n 
B 1 105 VAL 105 113 113 VAL VAL B . n 
B 1 106 ASN 106 114 114 ASN ASN B . n 
B 1 107 VAL 107 115 115 VAL VAL B . n 
B 1 108 GLN 108 116 116 GLN GLN B . n 
B 1 109 PRO 109 117 117 PRO PRO B . n 
B 1 110 TYR 110 118 118 TYR TYR B . n 
B 1 111 SER 111 119 119 SER SER B . n 
B 1 112 GLY 112 120 120 GLY GLY B . n 
B 1 113 SER 113 121 121 SER SER B . n 
B 1 114 PRO 114 122 122 PRO PRO B . n 
B 1 115 ALA 115 123 123 ALA ALA B . n 
B 1 116 ASN 116 124 124 ASN ASN B . n 
B 1 117 PHE 117 125 125 PHE PHE B . n 
B 1 118 ALA 118 126 126 ALA ALA B . n 
B 1 119 VAL 119 127 127 VAL VAL B . n 
B 1 120 TYR 120 128 128 TYR TYR B . n 
B 1 121 THR 121 129 129 THR THR B . n 
B 1 122 ALA 122 130 130 ALA ALA B . n 
B 1 123 LEU 123 131 131 LEU LEU B . n 
B 1 124 VAL 124 132 132 VAL VAL B . n 
B 1 125 GLU 125 133 133 GLU GLU B . n 
B 1 126 PRO 126 134 134 PRO PRO B . n 
B 1 127 HIS 127 135 135 HIS HIS B . n 
B 1 128 GLY 128 136 136 GLY GLY B . n 
B 1 129 ARG 129 137 137 ARG ARG B . n 
B 1 130 ILE 130 138 138 ILE ILE B . n 
B 1 131 MET 131 139 139 MET MET B . n 
B 1 132 GLY 132 140 140 GLY GLY B . n 
B 1 133 LEU 133 141 141 LEU LEU B . n 
B 1 134 ASP 134 142 142 ASP ASP B . n 
B 1 135 LEU 135 143 143 LEU LEU B . n 
B 1 136 PRO 136 144 144 PRO PRO B . n 
B 1 137 ASP 137 145 145 ASP ASP B . n 
B 1 138 GLY 138 146 146 GLY GLY B . n 
B 1 139 GLY 139 147 147 GLY GLY B . n 
B 1 140 HIS 140 148 148 HIS HIS B . n 
B 1 141 LEU 141 149 149 LEU LEU B . n 
B 1 142 THR 142 150 150 THR THR B . n 
B 1 143 HIS 143 151 151 HIS HIS B . n 
B 1 144 GLY 144 152 152 GLY GLY B . n 
B 1 145 PHE 145 153 153 PHE PHE B . n 
B 1 146 MET 146 154 154 MET MET B . n 
B 1 147 THR 147 155 155 THR THR B . n 
B 1 148 ASP 148 156 156 ASP ASP B . n 
B 1 149 LYS 149 157 157 LYS LYS B . n 
B 1 150 LYS 150 158 158 LYS LYS B . n 
B 1 151 LYS 151 159 159 LYS LYS B . n 
B 1 152 ILE 152 160 160 ILE ILE B . n 
B 1 153 SER 153 161 161 SER SER B . n 
B 1 154 ALA 154 162 162 ALA ALA B . n 
B 1 155 THR 155 163 163 THR THR B . n 
B 1 156 SER 156 164 164 SER SER B . n 
B 1 157 ILE 157 165 165 ILE ILE B . n 
B 1 158 PHE 158 166 166 PHE PHE B . n 
B 1 159 PHE 159 167 167 PHE PHE B . n 
B 1 160 GLU 160 168 168 GLU GLU B . n 
B 1 161 SER 161 169 169 SER SER B . n 
B 1 162 MET 162 170 170 MET MET B . n 
B 1 163 PRO 163 171 171 PRO PRO B . n 
B 1 164 TYR 164 172 172 TYR TYR B . n 
B 1 165 LYS 165 173 173 LYS LYS B . n 
B 1 166 VAL 166 174 174 VAL VAL B . n 
B 1 167 ASN 167 175 175 ASN ASN B . n 
B 1 168 PRO 168 176 176 PRO PRO B . n 
B 1 169 ASP 169 177 177 ASP ASP B . n 
B 1 170 THR 170 178 178 THR THR B . n 
B 1 171 GLY 171 179 179 GLY GLY B . n 
B 1 172 TYR 172 180 180 TYR TYR B . n 
B 1 173 ILE 173 181 181 ILE ILE B . n 
B 1 174 ASN 174 182 182 ASN ASN B . n 
B 1 175 TYR 175 183 183 TYR TYR B . n 
B 1 176 ASP 176 184 184 ASP ASP B . n 
B 1 177 GLN 177 185 185 GLN GLN B . n 
B 1 178 LEU 178 186 186 LEU LEU B . n 
B 1 179 GLU 179 187 187 GLU GLU B . n 
B 1 180 GLU 180 188 188 GLU GLU B . n 
B 1 181 ASN 181 189 189 ASN ASN B . n 
B 1 182 ALA 182 190 190 ALA ALA B . n 
B 1 183 ARG 183 191 191 ARG ARG B . n 
B 1 184 LEU 184 192 192 LEU LEU B . n 
B 1 185 PHE 185 193 193 PHE PHE B . n 
B 1 186 HIS 186 194 194 HIS HIS B . n 
B 1 187 PRO 187 195 195 PRO PRO B . n 
B 1 188 LYS 188 196 196 LYS LYS B . n 
B 1 189 LEU 189 197 197 LEU LEU B . n 
B 1 190 ILE 190 198 198 ILE ILE B . n 
B 1 191 ILE 191 199 199 ILE ILE B . n 
B 1 192 ALA 192 200 200 ALA ALA B . n 
B 1 193 GLY 193 201 201 GLY GLY B . n 
B 1 194 THR 194 202 202 THR THR B . n 
B 1 195 SER 195 203 203 SER SER B . n 
B 1 196 CYS 196 204 204 CYS CYS B . n 
B 1 197 TYR 197 205 205 TYR TYR B . n 
B 1 198 SER 198 206 206 SER SER B . n 
B 1 199 ARG 199 207 207 ARG ARG B . n 
B 1 200 ASN 200 208 208 ASN ASN B . n 
B 1 201 LEU 201 209 209 LEU LEU B . n 
B 1 202 GLU 202 210 210 GLU GLU B . n 
B 1 203 TYR 203 211 211 TYR TYR B . n 
B 1 204 ALA 204 212 212 ALA ALA B . n 
B 1 205 ARG 205 213 213 ARG ARG B . n 
B 1 206 LEU 206 214 214 LEU LEU B . n 
B 1 207 ARG 207 215 215 ARG ARG B . n 
B 1 208 LYS 208 216 216 LYS LYS B . n 
B 1 209 ILE 209 217 217 ILE ILE B . n 
B 1 210 ALA 210 218 218 ALA ALA B . n 
B 1 211 ASP 211 219 219 ASP ASP B . n 
B 1 212 GLU 212 220 220 GLU GLU B . n 
B 1 213 ASN 213 221 221 ASN ASN B . n 
B 1 214 GLY 214 222 222 GLY GLY B . n 
B 1 215 ALA 215 223 223 ALA ALA B . n 
B 1 216 TYR 216 224 224 TYR TYR B . n 
B 1 217 LEU 217 225 225 LEU LEU B . n 
B 1 218 MET 218 226 226 MET MET B . n 
B 1 219 ALA 219 227 227 ALA ALA B . n 
B 1 220 ASP 220 228 228 ASP ASP B . n 
B 1 221 MET 221 229 229 MET MET B . n 
B 1 222 ALA 222 230 230 ALA ALA B . n 
B 1 223 HIS 223 231 231 HIS HIS B . n 
B 1 224 ILE 224 232 232 ILE ILE B . n 
B 1 225 SER 225 233 233 SER SER B . n 
B 1 226 GLY 226 234 234 GLY GLY B . n 
B 1 227 LEU 227 235 235 LEU LEU B . n 
B 1 228 VAL 228 236 236 VAL VAL B . n 
B 1 229 ALA 229 237 237 ALA ALA B . n 
B 1 230 ALA 230 238 238 ALA ALA B . n 
B 1 231 GLY 231 239 239 GLY GLY B . n 
B 1 232 VAL 232 240 240 VAL VAL B . n 
B 1 233 VAL 233 241 241 VAL VAL B . n 
B 1 234 PRO 234 242 242 PRO PRO B . n 
B 1 235 SER 235 243 243 SER SER B . n 
B 1 236 PRO 236 244 244 PRO PRO B . n 
B 1 237 PHE 237 245 245 PHE PHE B . n 
B 1 238 GLU 238 246 246 GLU GLU B . n 
B 1 239 HIS 239 247 247 HIS HIS B . n 
B 1 240 CYS 240 248 248 CYS CYS B . n 
B 1 241 HIS 241 249 249 HIS HIS B . n 
B 1 242 VAL 242 250 250 VAL VAL B . n 
B 1 243 VAL 243 251 251 VAL VAL B . n 
B 1 244 THR 244 252 252 THR THR B . n 
B 1 245 THR 245 253 253 THR THR B . n 
B 1 246 THR 246 254 254 THR THR B . n 
B 1 247 THR 247 255 255 THR THR B . n 
B 1 248 HIS 248 256 256 HIS HIS B . n 
B 1 249 LYS 249 257 257 LYS LYS B . n 
B 1 250 THR 250 258 258 THR THR B . n 
B 1 251 LEU 251 259 259 LEU LEU B . n 
B 1 252 ARG 252 260 260 ARG ARG B . n 
B 1 253 GLY 253 261 261 GLY GLY B . n 
B 1 254 CYS 254 262 262 CYS CYS B . n 
B 1 255 ARG 255 263 263 ARG ARG B . n 
B 1 256 ALA 256 264 264 ALA ALA B . n 
B 1 257 GLY 257 265 265 GLY GLY B . n 
B 1 258 MET 258 266 266 MET MET B . n 
B 1 259 ILE 259 267 267 ILE ILE B . n 
B 1 260 PHE 260 268 268 PHE PHE B . n 
B 1 261 TYR 261 269 269 TYR TYR B . n 
B 1 262 ARG 262 270 270 ARG ARG B . n 
B 1 263 LYS 263 271 271 LYS LYS B . n 
B 1 264 GLY 264 272 272 GLY GLY B . n 
B 1 265 VAL 265 273 273 VAL VAL B . n 
B 1 266 LYS 266 274 274 LYS LYS B . n 
B 1 267 SER 267 275 275 SER SER B . n 
B 1 268 VAL 268 276 276 VAL VAL B . n 
B 1 269 ASP 269 277 277 ASP ASP B . n 
B 1 270 PRO 270 278 278 PRO PRO B . n 
B 1 271 ALA 271 279 279 ALA ALA B . n 
B 1 272 THR 272 280 280 THR THR B . n 
B 1 273 GLY 273 281 281 GLY GLY B . n 
B 1 274 LYS 274 282 282 LYS LYS B . n 
B 1 275 GLU 275 283 283 GLU GLU B . n 
B 1 276 ILE 276 284 284 ILE ILE B . n 
B 1 277 LEU 277 285 285 LEU LEU B . n 
B 1 278 TYR 278 286 286 TYR TYR B . n 
B 1 279 ASN 279 287 287 ASN ASN B . n 
B 1 280 LEU 280 288 288 LEU LEU B . n 
B 1 281 GLU 281 289 289 GLU GLU B . n 
B 1 282 SER 282 290 290 SER SER B . n 
B 1 283 LEU 283 291 291 LEU LEU B . n 
B 1 284 ILE 284 292 292 ILE ILE B . n 
B 1 285 ASN 285 293 293 ASN ASN B . n 
B 1 286 SER 286 294 294 SER SER B . n 
B 1 287 ALA 287 295 295 ALA ALA B . n 
B 1 288 VAL 288 296 296 VAL VAL B . n 
B 1 289 PHE 289 297 297 PHE PHE B . n 
B 1 290 PRO 290 298 298 PRO PRO B . n 
B 1 291 GLY 291 299 299 GLY GLY B . n 
B 1 292 LEU 292 300 300 LEU LEU B . n 
B 1 293 GLN 293 301 301 GLN GLN B . n 
B 1 294 GLY 294 302 302 GLY GLY B . n 
B 1 295 GLY 295 303 303 GLY GLY B . n 
B 1 296 PRO 296 304 304 PRO PRO B . n 
B 1 297 HIS 297 305 305 HIS HIS B . n 
B 1 298 ASN 298 306 306 ASN ASN B . n 
B 1 299 HIS 299 307 307 HIS HIS B . n 
B 1 300 ALA 300 308 308 ALA ALA B . n 
B 1 301 ILE 301 309 309 ILE ILE B . n 
B 1 302 ALA 302 310 310 ALA ALA B . n 
B 1 303 GLY 303 311 311 GLY GLY B . n 
B 1 304 VAL 304 312 312 VAL VAL B . n 
B 1 305 ALA 305 313 313 ALA ALA B . n 
B 1 306 VAL 306 314 314 VAL VAL B . n 
B 1 307 ALA 307 315 315 ALA ALA B . n 
B 1 308 LEU 308 316 316 LEU LEU B . n 
B 1 309 LYS 309 317 317 LYS LYS B . n 
B 1 310 GLN 310 318 318 GLN GLN B . n 
B 1 311 ALA 311 319 319 ALA ALA B . n 
B 1 312 MET 312 320 320 MET MET B . n 
B 1 313 THR 313 321 321 THR THR B . n 
B 1 314 LEU 314 322 322 LEU LEU B . n 
B 1 315 GLU 315 323 323 GLU GLU B . n 
B 1 316 PHE 316 324 324 PHE PHE B . n 
B 1 317 LYS 317 325 325 LYS LYS B . n 
B 1 318 VAL 318 326 326 VAL VAL B . n 
B 1 319 TYR 319 327 327 TYR TYR B . n 
B 1 320 GLN 320 328 328 GLN GLN B . n 
B 1 321 HIS 321 329 329 HIS HIS B . n 
B 1 322 GLN 322 330 330 GLN GLN B . n 
B 1 323 VAL 323 331 331 VAL VAL B . n 
B 1 324 VAL 324 332 332 VAL VAL B . n 
B 1 325 ALA 325 333 333 ALA ALA B . n 
B 1 326 ASN 326 334 334 ASN ASN B . n 
B 1 327 CYS 327 335 335 CYS CYS B . n 
B 1 328 ARG 328 336 336 ARG ARG B . n 
B 1 329 ALA 329 337 337 ALA ALA B . n 
B 1 330 LEU 330 338 338 LEU LEU B . n 
B 1 331 SER 331 339 339 SER SER B . n 
B 1 332 GLU 332 340 340 GLU GLU B . n 
B 1 333 ALA 333 341 341 ALA ALA B . n 
B 1 334 LEU 334 342 342 LEU LEU B . n 
B 1 335 THR 335 343 343 THR THR B . n 
B 1 336 GLU 336 344 344 GLU GLU B . n 
B 1 337 LEU 337 345 345 LEU LEU B . n 
B 1 338 GLY 338 346 346 GLY GLY B . n 
B 1 339 TYR 339 347 347 TYR TYR B . n 
B 1 340 LYS 340 348 348 LYS LYS B . n 
B 1 341 ILE 341 349 349 ILE ILE B . n 
B 1 342 VAL 342 350 350 VAL VAL B . n 
B 1 343 THR 343 351 351 THR THR B . n 
B 1 344 GLY 344 352 352 GLY GLY B . n 
B 1 345 GLY 345 353 353 GLY GLY B . n 
B 1 346 SER 346 354 354 SER SER B . n 
B 1 347 ASP 347 355 355 ASP ASP B . n 
B 1 348 ASN 348 356 356 ASN ASN B . n 
B 1 349 HIS 349 357 357 HIS HIS B . n 
B 1 350 LEU 350 358 358 LEU LEU B . n 
B 1 351 ILE 351 359 359 ILE ILE B . n 
B 1 352 LEU 352 360 360 LEU LEU B . n 
B 1 353 VAL 353 361 361 VAL VAL B . n 
B 1 354 ASP 354 362 362 ASP ASP B . n 
B 1 355 LEU 355 363 363 LEU LEU B . n 
B 1 356 ARG 356 364 364 ARG ARG B . n 
B 1 357 SER 357 365 365 SER SER B . n 
B 1 358 LYS 358 366 366 LYS LYS B . n 
B 1 359 GLY 359 367 367 GLY GLY B . n 
B 1 360 THR 360 368 368 THR THR B . n 
B 1 361 ASP 361 369 369 ASP ASP B . n 
B 1 362 GLY 362 370 370 GLY GLY B . n 
B 1 363 GLY 363 371 371 GLY GLY B . n 
B 1 364 ARG 364 372 372 ARG ARG B . n 
B 1 365 ALA 365 373 373 ALA ALA B . n 
B 1 366 GLU 366 374 374 GLU GLU B . n 
B 1 367 LYS 367 375 375 LYS LYS B . n 
B 1 368 VAL 368 376 376 VAL VAL B . n 
B 1 369 LEU 369 377 377 LEU LEU B . n 
B 1 370 GLU 370 378 378 GLU GLU B . n 
B 1 371 ALA 371 379 379 ALA ALA B . n 
B 1 372 CYS 372 380 380 CYS CYS B . n 
B 1 373 SER 373 381 381 SER SER B . n 
B 1 374 ILE 374 382 382 ILE ILE B . n 
B 1 375 ALA 375 383 383 ALA ALA B . n 
B 1 376 CYS 376 384 384 CYS CYS B . n 
B 1 377 ASN 377 385 385 ASN ASN B . n 
B 1 378 LYS 378 386 386 LYS LYS B . n 
B 1 379 ASN 379 387 387 ASN ASN B . n 
B 1 380 THR 380 388 388 THR THR B . n 
B 1 381 CYS 381 389 389 CYS CYS B . n 
B 1 382 PRO 382 390 390 PRO PRO B . n 
B 1 383 GLY 383 391 391 GLY GLY B . n 
B 1 384 ASP 384 392 392 ASP ASP B . n 
B 1 385 ARG 385 393 393 ARG ARG B . n 
B 1 386 SER 386 394 394 SER SER B . n 
B 1 387 ALA 387 395 395 ALA ALA B . n 
B 1 388 LEU 388 396 396 LEU LEU B . n 
B 1 389 ARG 389 397 397 ARG ARG B . n 
B 1 390 PRO 390 398 398 PRO PRO B . n 
B 1 391 SER 391 399 399 SER SER B . n 
B 1 392 GLY 392 400 400 GLY GLY B . n 
B 1 393 LEU 393 401 401 LEU LEU B . n 
B 1 394 ARG 394 402 402 ARG ARG B . n 
B 1 395 LEU 395 403 403 LEU LEU B . n 
B 1 396 GLY 396 404 404 GLY GLY B . n 
B 1 397 THR 397 405 405 THR THR B . n 
B 1 398 PRO 398 406 406 PRO PRO B . n 
B 1 399 ALA 399 407 407 ALA ALA B . n 
B 1 400 LEU 400 408 408 LEU LEU B . n 
B 1 401 THR 401 409 409 THR THR B . n 
B 1 402 SER 402 410 410 SER SER B . n 
B 1 403 ARG 403 411 411 ARG ARG B . n 
B 1 404 GLY 404 412 412 GLY GLY B . n 
B 1 405 LEU 405 413 413 LEU LEU B . n 
B 1 406 LEU 406 414 414 LEU LEU B . n 
B 1 407 GLU 407 415 415 GLU GLU B . n 
B 1 408 LYS 408 416 416 LYS LYS B . n 
B 1 409 ASP 409 417 417 ASP ASP B . n 
B 1 410 PHE 410 418 418 PHE PHE B . n 
B 1 411 GLN 411 419 419 GLN GLN B . n 
B 1 412 LYS 412 420 420 LYS LYS B . n 
B 1 413 VAL 413 421 421 VAL VAL B . n 
B 1 414 ALA 414 422 422 ALA ALA B . n 
B 1 415 HIS 415 423 423 HIS HIS B . n 
B 1 416 PHE 416 424 424 PHE PHE B . n 
B 1 417 ILE 417 425 425 ILE ILE B . n 
B 1 418 HIS 418 426 426 HIS HIS B . n 
B 1 419 ARG 419 427 427 ARG ARG B . n 
B 1 420 GLY 420 428 428 GLY GLY B . n 
B 1 421 ILE 421 429 429 ILE ILE B . n 
B 1 422 GLU 422 430 430 GLU GLU B . n 
B 1 423 LEU 423 431 431 LEU LEU B . n 
B 1 424 THR 424 432 432 THR THR B . n 
B 1 425 LEU 425 433 433 LEU LEU B . n 
B 1 426 GLN 426 434 434 GLN GLN B . n 
B 1 427 ILE 427 435 435 ILE ILE B . n 
B 1 428 GLN 428 436 436 GLN GLN B . n 
B 1 429 SER 429 437 437 SER SER B . n 
B 1 430 ASP 430 438 438 ASP ASP B . n 
B 1 431 THR 431 439 439 THR THR B . n 
B 1 432 GLY 432 440 440 GLY GLY B . n 
B 1 433 VAL 433 441 441 VAL VAL B . n 
B 1 434 ALA 434 442 442 ALA ALA B . n 
B 1 435 ALA 435 443 443 ALA ALA B . n 
B 1 436 THR 436 444 444 THR THR B . n 
B 1 437 LEU 437 445 445 LEU LEU B . n 
B 1 438 LYS 438 446 446 LYS LYS B . n 
B 1 439 GLU 439 447 447 GLU GLU B . n 
B 1 440 PHE 440 448 448 PHE PHE B . n 
B 1 441 LYS 441 449 449 LYS LYS B . n 
B 1 442 GLU 442 450 450 GLU GLU B . n 
B 1 443 ARG 443 451 451 ARG ARG B . n 
B 1 444 LEU 444 452 452 LEU LEU B . n 
B 1 445 ALA 445 453 453 ALA ALA B . n 
B 1 446 GLY 446 454 454 GLY GLY B . n 
B 1 447 ASP 447 455 455 ASP ASP B . n 
B 1 448 LYS 448 456 456 LYS LYS B . n 
B 1 449 TYR 449 457 457 TYR TYR B . n 
B 1 450 GLN 450 458 458 GLN GLN B . n 
B 1 451 ALA 451 459 459 ALA ALA B . n 
B 1 452 ALA 452 460 460 ALA ALA B . n 
B 1 453 VAL 453 461 461 VAL VAL B . n 
B 1 454 GLN 454 462 462 GLN GLN B . n 
B 1 455 ALA 455 463 463 ALA ALA B . n 
B 1 456 LEU 456 464 464 LEU LEU B . n 
B 1 457 ARG 457 465 465 ARG ARG B . n 
B 1 458 GLU 458 466 466 GLU GLU B . n 
B 1 459 GLU 459 467 467 GLU GLU B . n 
B 1 460 VAL 460 468 468 VAL VAL B . n 
B 1 461 GLU 461 469 469 GLU GLU B . n 
B 1 462 SER 462 470 470 SER SER B . n 
B 1 463 PHE 463 471 471 PHE PHE B . n 
B 1 464 ALA 464 472 472 ALA ALA B . n 
B 1 465 SER 465 473 473 SER SER B . n 
B 1 466 LEU 466 474 474 LEU LEU B . n 
B 1 467 PHE 467 475 475 PHE PHE B . n 
B 1 468 PRO 468 476 476 PRO PRO B . n 
B 1 469 LEU 469 477 477 LEU LEU B . n 
B 1 470 PRO 470 478 478 PRO PRO B . n 
B 1 471 GLY 471 479 479 GLY GLY B . n 
B 1 472 LEU 472 480 480 LEU LEU B . n 
C 1 1   GLN 1   9   9   GLN GLN C . n 
C 1 2   GLY 2   10  10  GLY GLY C . n 
C 1 3   ASP 3   11  11  ASP ASP C . n 
C 1 4   ALA 4   12  12  ALA ALA C . n 
C 1 5   ASP 5   13  13  ASP ASP C . n 
C 1 6   LEU 6   14  14  LEU LEU C . n 
C 1 7   TRP 7   15  15  TRP TRP C . n 
C 1 8   SER 8   16  16  SER SER C . n 
C 1 9   SER 9   17  17  SER SER C . n 
C 1 10  HIS 10  18  18  HIS HIS C . n 
C 1 11  ASP 11  19  19  ASP ASP C . n 
C 1 12  ALA 12  20  20  ALA ALA C . n 
C 1 13  MET 13  21  21  MET MET C . n 
C 1 14  LEU 14  22  22  LEU LEU C . n 
C 1 15  ALA 15  23  23  ALA ALA C . n 
C 1 16  GLN 16  24  24  GLN GLN C . n 
C 1 17  PRO 17  25  25  PRO PRO C . n 
C 1 18  LEU 18  26  26  LEU LEU C . n 
C 1 19  LYS 19  27  27  LYS LYS C . n 
C 1 20  ASP 20  28  28  ASP ASP C . n 
C 1 21  SER 21  29  29  SER SER C . n 
C 1 22  ASP 22  30  30  ASP ASP C . n 
C 1 23  VAL 23  31  31  VAL VAL C . n 
C 1 24  GLU 24  32  32  GLU GLU C . n 
C 1 25  VAL 25  33  33  VAL VAL C . n 
C 1 26  TYR 26  34  34  TYR TYR C . n 
C 1 27  ASN 27  35  35  ASN ASN C . n 
C 1 28  ILE 28  36  36  ILE ILE C . n 
C 1 29  ILE 29  37  37  ILE ILE C . n 
C 1 30  LYS 30  38  38  LYS LYS C . n 
C 1 31  LYS 31  39  39  LYS LYS C . n 
C 1 32  GLU 32  40  40  GLU GLU C . n 
C 1 33  SER 33  41  41  SER SER C . n 
C 1 34  ASN 34  42  42  ASN ASN C . n 
C 1 35  ARG 35  43  43  ARG ARG C . n 
C 1 36  GLN 36  44  44  GLN GLN C . n 
C 1 37  ARG 37  45  45  ARG ARG C . n 
C 1 38  VAL 38  46  46  VAL VAL C . n 
C 1 39  GLY 39  47  47  GLY GLY C . n 
C 1 40  LEU 40  48  48  LEU LEU C . n 
C 1 41  GLU 41  49  49  GLU GLU C . n 
C 1 42  LEU 42  50  50  LEU LEU C . n 
C 1 43  ILE 43  51  51  ILE ILE C . n 
C 1 44  ALA 44  52  52  ALA ALA C . n 
C 1 45  SER 45  53  53  SER SER C . n 
C 1 46  GLU 46  54  54  GLU GLU C . n 
C 1 47  ASN 47  55  55  ASN ASN C . n 
C 1 48  PHE 48  56  56  PHE PHE C . n 
C 1 49  ALA 49  57  57  ALA ALA C . n 
C 1 50  SER 50  58  58  SER SER C . n 
C 1 51  ARG 51  59  59  ARG ARG C . n 
C 1 52  ALA 52  60  60  ALA ALA C . n 
C 1 53  VAL 53  61  61  VAL VAL C . n 
C 1 54  LEU 54  62  62  LEU LEU C . n 
C 1 55  GLU 55  63  63  GLU GLU C . n 
C 1 56  ALA 56  64  64  ALA ALA C . n 
C 1 57  LEU 57  65  65  LEU LEU C . n 
C 1 58  GLY 58  66  66  GLY GLY C . n 
C 1 59  SER 59  67  67  SER SER C . n 
C 1 60  CYS 60  68  68  CYS CYS C . n 
C 1 61  LEU 61  69  69  LEU LEU C . n 
C 1 62  ASN 62  70  70  ASN ASN C . n 
C 1 63  ASN 63  71  71  ASN ASN C . n 
C 1 64  LYS 64  72  72  LYS LYS C . n 
C 1 65  TYR 65  73  73  TYR TYR C . n 
C 1 66  SER 66  74  74  SER SER C . n 
C 1 67  GLU 67  75  75  GLU GLU C . n 
C 1 68  GLY 68  76  76  GLY GLY C . n 
C 1 69  TYR 69  77  77  TYR TYR C . n 
C 1 70  PRO 70  78  78  PRO PRO C . n 
C 1 71  GLY 71  79  79  GLY GLY C . n 
C 1 72  GLN 72  80  80  GLN GLN C . n 
C 1 73  ARG 73  81  81  ARG ARG C . n 
C 1 74  TYR 74  82  82  TYR TYR C . n 
C 1 75  TYR 75  83  83  TYR TYR C . n 
C 1 76  GLY 76  84  84  GLY GLY C . n 
C 1 77  GLY 77  85  85  GLY GLY C . n 
C 1 78  THR 78  86  86  THR THR C . n 
C 1 79  GLU 79  87  87  GLU GLU C . n 
C 1 80  PHE 80  88  88  PHE PHE C . n 
C 1 81  ILE 81  89  89  ILE ILE C . n 
C 1 82  ASP 82  90  90  ASP ASP C . n 
C 1 83  GLU 83  91  91  GLU GLU C . n 
C 1 84  LEU 84  92  92  LEU LEU C . n 
C 1 85  GLU 85  93  93  GLU GLU C . n 
C 1 86  THR 86  94  94  THR THR C . n 
C 1 87  LEU 87  95  95  LEU LEU C . n 
C 1 88  CYS 88  96  96  CYS CYS C . n 
C 1 89  GLN 89  97  97  GLN GLN C . n 
C 1 90  LYS 90  98  98  LYS LYS C . n 
C 1 91  ARG 91  99  99  ARG ARG C . n 
C 1 92  ALA 92  100 100 ALA ALA C . n 
C 1 93  LEU 93  101 101 LEU LEU C . n 
C 1 94  GLN 94  102 102 GLN GLN C . n 
C 1 95  ALA 95  103 103 ALA ALA C . n 
C 1 96  TYR 96  104 104 TYR TYR C . n 
C 1 97  LYS 97  105 105 LYS LYS C . n 
C 1 98  LEU 98  106 106 LEU LEU C . n 
C 1 99  ASP 99  107 107 ASP ASP C . n 
C 1 100 PRO 100 108 108 PRO PRO C . n 
C 1 101 GLN 101 109 109 GLN GLN C . n 
C 1 102 CYS 102 110 110 CYS CYS C . n 
C 1 103 TRP 103 111 111 TRP TRP C . n 
C 1 104 GLY 104 112 112 GLY GLY C . n 
C 1 105 VAL 105 113 113 VAL VAL C . n 
C 1 106 ASN 106 114 114 ASN ASN C . n 
C 1 107 VAL 107 115 115 VAL VAL C . n 
C 1 108 GLN 108 116 116 GLN GLN C . n 
C 1 109 PRO 109 117 117 PRO PRO C . n 
C 1 110 TYR 110 118 118 TYR TYR C . n 
C 1 111 SER 111 119 119 SER SER C . n 
C 1 112 GLY 112 120 120 GLY GLY C . n 
C 1 113 SER 113 121 121 SER SER C . n 
C 1 114 PRO 114 122 122 PRO PRO C . n 
C 1 115 ALA 115 123 123 ALA ALA C . n 
C 1 116 ASN 116 124 124 ASN ASN C . n 
C 1 117 PHE 117 125 125 PHE PHE C . n 
C 1 118 ALA 118 126 126 ALA ALA C . n 
C 1 119 VAL 119 127 127 VAL VAL C . n 
C 1 120 TYR 120 128 128 TYR TYR C . n 
C 1 121 THR 121 129 129 THR THR C . n 
C 1 122 ALA 122 130 130 ALA ALA C . n 
C 1 123 LEU 123 131 131 LEU LEU C . n 
C 1 124 VAL 124 132 132 VAL VAL C . n 
C 1 125 GLU 125 133 133 GLU GLU C . n 
C 1 126 PRO 126 134 134 PRO PRO C . n 
C 1 127 HIS 127 135 135 HIS HIS C . n 
C 1 128 GLY 128 136 136 GLY GLY C . n 
C 1 129 ARG 129 137 137 ARG ARG C . n 
C 1 130 ILE 130 138 138 ILE ILE C . n 
C 1 131 MET 131 139 139 MET MET C . n 
C 1 132 GLY 132 140 140 GLY GLY C . n 
C 1 133 LEU 133 141 141 LEU LEU C . n 
C 1 134 ASP 134 142 142 ASP ASP C . n 
C 1 135 LEU 135 143 143 LEU LEU C . n 
C 1 136 PRO 136 144 144 PRO PRO C . n 
C 1 137 ASP 137 145 145 ASP ASP C . n 
C 1 138 GLY 138 146 146 GLY GLY C . n 
C 1 139 GLY 139 147 147 GLY GLY C . n 
C 1 140 HIS 140 148 148 HIS HIS C . n 
C 1 141 LEU 141 149 149 LEU LEU C . n 
C 1 142 THR 142 150 150 THR THR C . n 
C 1 143 HIS 143 151 151 HIS HIS C . n 
C 1 144 GLY 144 152 152 GLY GLY C . n 
C 1 145 PHE 145 153 153 PHE PHE C . n 
C 1 146 MET 146 154 154 MET MET C . n 
C 1 147 THR 147 155 155 THR THR C . n 
C 1 148 ASP 148 156 156 ASP ASP C . n 
C 1 149 LYS 149 157 157 LYS LYS C . n 
C 1 150 LYS 150 158 158 LYS LYS C . n 
C 1 151 LYS 151 159 159 LYS LYS C . n 
C 1 152 ILE 152 160 160 ILE ILE C . n 
C 1 153 SER 153 161 161 SER SER C . n 
C 1 154 ALA 154 162 162 ALA ALA C . n 
C 1 155 THR 155 163 163 THR THR C . n 
C 1 156 SER 156 164 164 SER SER C . n 
C 1 157 ILE 157 165 165 ILE ILE C . n 
C 1 158 PHE 158 166 166 PHE PHE C . n 
C 1 159 PHE 159 167 167 PHE PHE C . n 
C 1 160 GLU 160 168 168 GLU GLU C . n 
C 1 161 SER 161 169 169 SER SER C . n 
C 1 162 MET 162 170 170 MET MET C . n 
C 1 163 PRO 163 171 171 PRO PRO C . n 
C 1 164 TYR 164 172 172 TYR TYR C . n 
C 1 165 LYS 165 173 173 LYS LYS C . n 
C 1 166 VAL 166 174 174 VAL VAL C . n 
C 1 167 ASN 167 175 175 ASN ASN C . n 
C 1 168 PRO 168 176 176 PRO PRO C . n 
C 1 169 ASP 169 177 177 ASP ASP C . n 
C 1 170 THR 170 178 178 THR THR C . n 
C 1 171 GLY 171 179 179 GLY GLY C . n 
C 1 172 TYR 172 180 180 TYR TYR C . n 
C 1 173 ILE 173 181 181 ILE ILE C . n 
C 1 174 ASN 174 182 182 ASN ASN C . n 
C 1 175 TYR 175 183 183 TYR TYR C . n 
C 1 176 ASP 176 184 184 ASP ASP C . n 
C 1 177 GLN 177 185 185 GLN GLN C . n 
C 1 178 LEU 178 186 186 LEU LEU C . n 
C 1 179 GLU 179 187 187 GLU GLU C . n 
C 1 180 GLU 180 188 188 GLU GLU C . n 
C 1 181 ASN 181 189 189 ASN ASN C . n 
C 1 182 ALA 182 190 190 ALA ALA C . n 
C 1 183 ARG 183 191 191 ARG ARG C . n 
C 1 184 LEU 184 192 192 LEU LEU C . n 
C 1 185 PHE 185 193 193 PHE PHE C . n 
C 1 186 HIS 186 194 194 HIS HIS C . n 
C 1 187 PRO 187 195 195 PRO PRO C . n 
C 1 188 LYS 188 196 196 LYS LYS C . n 
C 1 189 LEU 189 197 197 LEU LEU C . n 
C 1 190 ILE 190 198 198 ILE ILE C . n 
C 1 191 ILE 191 199 199 ILE ILE C . n 
C 1 192 ALA 192 200 200 ALA ALA C . n 
C 1 193 GLY 193 201 201 GLY GLY C . n 
C 1 194 THR 194 202 202 THR THR C . n 
C 1 195 SER 195 203 203 SER SER C . n 
C 1 196 CYS 196 204 204 CYS CYS C . n 
C 1 197 TYR 197 205 205 TYR TYR C . n 
C 1 198 SER 198 206 206 SER SER C . n 
C 1 199 ARG 199 207 207 ARG ARG C . n 
C 1 200 ASN 200 208 208 ASN ASN C . n 
C 1 201 LEU 201 209 209 LEU LEU C . n 
C 1 202 GLU 202 210 210 GLU GLU C . n 
C 1 203 TYR 203 211 211 TYR TYR C . n 
C 1 204 ALA 204 212 212 ALA ALA C . n 
C 1 205 ARG 205 213 213 ARG ARG C . n 
C 1 206 LEU 206 214 214 LEU LEU C . n 
C 1 207 ARG 207 215 215 ARG ARG C . n 
C 1 208 LYS 208 216 216 LYS LYS C . n 
C 1 209 ILE 209 217 217 ILE ILE C . n 
C 1 210 ALA 210 218 218 ALA ALA C . n 
C 1 211 ASP 211 219 219 ASP ASP C . n 
C 1 212 GLU 212 220 220 GLU GLU C . n 
C 1 213 ASN 213 221 221 ASN ASN C . n 
C 1 214 GLY 214 222 222 GLY GLY C . n 
C 1 215 ALA 215 223 223 ALA ALA C . n 
C 1 216 TYR 216 224 224 TYR TYR C . n 
C 1 217 LEU 217 225 225 LEU LEU C . n 
C 1 218 MET 218 226 226 MET MET C . n 
C 1 219 ALA 219 227 227 ALA ALA C . n 
C 1 220 ASP 220 228 228 ASP ASP C . n 
C 1 221 MET 221 229 229 MET MET C . n 
C 1 222 ALA 222 230 230 ALA ALA C . n 
C 1 223 HIS 223 231 231 HIS HIS C . n 
C 1 224 ILE 224 232 232 ILE ILE C . n 
C 1 225 SER 225 233 233 SER SER C . n 
C 1 226 GLY 226 234 234 GLY GLY C . n 
C 1 227 LEU 227 235 235 LEU LEU C . n 
C 1 228 VAL 228 236 236 VAL VAL C . n 
C 1 229 ALA 229 237 237 ALA ALA C . n 
C 1 230 ALA 230 238 238 ALA ALA C . n 
C 1 231 GLY 231 239 239 GLY GLY C . n 
C 1 232 VAL 232 240 240 VAL VAL C . n 
C 1 233 VAL 233 241 241 VAL VAL C . n 
C 1 234 PRO 234 242 242 PRO PRO C . n 
C 1 235 SER 235 243 243 SER SER C . n 
C 1 236 PRO 236 244 244 PRO PRO C . n 
C 1 237 PHE 237 245 245 PHE PHE C . n 
C 1 238 GLU 238 246 246 GLU GLU C . n 
C 1 239 HIS 239 247 247 HIS HIS C . n 
C 1 240 CYS 240 248 248 CYS CYS C . n 
C 1 241 HIS 241 249 249 HIS HIS C . n 
C 1 242 VAL 242 250 250 VAL VAL C . n 
C 1 243 VAL 243 251 251 VAL VAL C . n 
C 1 244 THR 244 252 252 THR THR C . n 
C 1 245 THR 245 253 253 THR THR C . n 
C 1 246 THR 246 254 254 THR THR C . n 
C 1 247 THR 247 255 255 THR THR C . n 
C 1 248 HIS 248 256 256 HIS HIS C . n 
C 1 249 LYS 249 257 257 LYS LYS C . n 
C 1 250 THR 250 258 258 THR THR C . n 
C 1 251 LEU 251 259 259 LEU LEU C . n 
C 1 252 ARG 252 260 260 ARG ARG C . n 
C 1 253 GLY 253 261 261 GLY GLY C . n 
C 1 254 CYS 254 262 262 CYS CYS C . n 
C 1 255 ARG 255 263 263 ARG ARG C . n 
C 1 256 ALA 256 264 264 ALA ALA C . n 
C 1 257 GLY 257 265 265 GLY GLY C . n 
C 1 258 MET 258 266 266 MET MET C . n 
C 1 259 ILE 259 267 267 ILE ILE C . n 
C 1 260 PHE 260 268 268 PHE PHE C . n 
C 1 261 TYR 261 269 269 TYR TYR C . n 
C 1 262 ARG 262 270 270 ARG ARG C . n 
C 1 263 LYS 263 271 271 LYS LYS C . n 
C 1 264 GLY 264 272 272 GLY GLY C . n 
C 1 265 VAL 265 273 273 VAL VAL C . n 
C 1 266 LYS 266 274 274 LYS LYS C . n 
C 1 267 SER 267 275 275 SER SER C . n 
C 1 268 VAL 268 276 276 VAL VAL C . n 
C 1 269 ASP 269 277 277 ASP ASP C . n 
C 1 270 PRO 270 278 278 PRO PRO C . n 
C 1 271 ALA 271 279 279 ALA ALA C . n 
C 1 272 THR 272 280 280 THR THR C . n 
C 1 273 GLY 273 281 281 GLY GLY C . n 
C 1 274 LYS 274 282 282 LYS LYS C . n 
C 1 275 GLU 275 283 283 GLU GLU C . n 
C 1 276 ILE 276 284 284 ILE ILE C . n 
C 1 277 LEU 277 285 285 LEU LEU C . n 
C 1 278 TYR 278 286 286 TYR TYR C . n 
C 1 279 ASN 279 287 287 ASN ASN C . n 
C 1 280 LEU 280 288 288 LEU LEU C . n 
C 1 281 GLU 281 289 289 GLU GLU C . n 
C 1 282 SER 282 290 290 SER SER C . n 
C 1 283 LEU 283 291 291 LEU LEU C . n 
C 1 284 ILE 284 292 292 ILE ILE C . n 
C 1 285 ASN 285 293 293 ASN ASN C . n 
C 1 286 SER 286 294 294 SER SER C . n 
C 1 287 ALA 287 295 295 ALA ALA C . n 
C 1 288 VAL 288 296 296 VAL VAL C . n 
C 1 289 PHE 289 297 297 PHE PHE C . n 
C 1 290 PRO 290 298 298 PRO PRO C . n 
C 1 291 GLY 291 299 299 GLY GLY C . n 
C 1 292 LEU 292 300 300 LEU LEU C . n 
C 1 293 GLN 293 301 301 GLN GLN C . n 
C 1 294 GLY 294 302 302 GLY GLY C . n 
C 1 295 GLY 295 303 303 GLY GLY C . n 
C 1 296 PRO 296 304 304 PRO PRO C . n 
C 1 297 HIS 297 305 305 HIS HIS C . n 
C 1 298 ASN 298 306 306 ASN ASN C . n 
C 1 299 HIS 299 307 307 HIS HIS C . n 
C 1 300 ALA 300 308 308 ALA ALA C . n 
C 1 301 ILE 301 309 309 ILE ILE C . n 
C 1 302 ALA 302 310 310 ALA ALA C . n 
C 1 303 GLY 303 311 311 GLY GLY C . n 
C 1 304 VAL 304 312 312 VAL VAL C . n 
C 1 305 ALA 305 313 313 ALA ALA C . n 
C 1 306 VAL 306 314 314 VAL VAL C . n 
C 1 307 ALA 307 315 315 ALA ALA C . n 
C 1 308 LEU 308 316 316 LEU LEU C . n 
C 1 309 LYS 309 317 317 LYS LYS C . n 
C 1 310 GLN 310 318 318 GLN GLN C . n 
C 1 311 ALA 311 319 319 ALA ALA C . n 
C 1 312 MET 312 320 320 MET MET C . n 
C 1 313 THR 313 321 321 THR THR C . n 
C 1 314 LEU 314 322 322 LEU LEU C . n 
C 1 315 GLU 315 323 323 GLU GLU C . n 
C 1 316 PHE 316 324 324 PHE PHE C . n 
C 1 317 LYS 317 325 325 LYS LYS C . n 
C 1 318 VAL 318 326 326 VAL VAL C . n 
C 1 319 TYR 319 327 327 TYR TYR C . n 
C 1 320 GLN 320 328 328 GLN GLN C . n 
C 1 321 HIS 321 329 329 HIS HIS C . n 
C 1 322 GLN 322 330 330 GLN GLN C . n 
C 1 323 VAL 323 331 331 VAL VAL C . n 
C 1 324 VAL 324 332 332 VAL VAL C . n 
C 1 325 ALA 325 333 333 ALA ALA C . n 
C 1 326 ASN 326 334 334 ASN ASN C . n 
C 1 327 CYS 327 335 335 CYS CYS C . n 
C 1 328 ARG 328 336 336 ARG ARG C . n 
C 1 329 ALA 329 337 337 ALA ALA C . n 
C 1 330 LEU 330 338 338 LEU LEU C . n 
C 1 331 SER 331 339 339 SER SER C . n 
C 1 332 GLU 332 340 340 GLU GLU C . n 
C 1 333 ALA 333 341 341 ALA ALA C . n 
C 1 334 LEU 334 342 342 LEU LEU C . n 
C 1 335 THR 335 343 343 THR THR C . n 
C 1 336 GLU 336 344 344 GLU GLU C . n 
C 1 337 LEU 337 345 345 LEU LEU C . n 
C 1 338 GLY 338 346 346 GLY GLY C . n 
C 1 339 TYR 339 347 347 TYR TYR C . n 
C 1 340 LYS 340 348 348 LYS LYS C . n 
C 1 341 ILE 341 349 349 ILE ILE C . n 
C 1 342 VAL 342 350 350 VAL VAL C . n 
C 1 343 THR 343 351 351 THR THR C . n 
C 1 344 GLY 344 352 352 GLY GLY C . n 
C 1 345 GLY 345 353 353 GLY GLY C . n 
C 1 346 SER 346 354 354 SER SER C . n 
C 1 347 ASP 347 355 355 ASP ASP C . n 
C 1 348 ASN 348 356 356 ASN ASN C . n 
C 1 349 HIS 349 357 357 HIS HIS C . n 
C 1 350 LEU 350 358 358 LEU LEU C . n 
C 1 351 ILE 351 359 359 ILE ILE C . n 
C 1 352 LEU 352 360 360 LEU LEU C . n 
C 1 353 VAL 353 361 361 VAL VAL C . n 
C 1 354 ASP 354 362 362 ASP ASP C . n 
C 1 355 LEU 355 363 363 LEU LEU C . n 
C 1 356 ARG 356 364 364 ARG ARG C . n 
C 1 357 SER 357 365 365 SER SER C . n 
C 1 358 LYS 358 366 366 LYS LYS C . n 
C 1 359 GLY 359 367 367 GLY GLY C . n 
C 1 360 THR 360 368 368 THR THR C . n 
C 1 361 ASP 361 369 369 ASP ASP C . n 
C 1 362 GLY 362 370 370 GLY GLY C . n 
C 1 363 GLY 363 371 371 GLY GLY C . n 
C 1 364 ARG 364 372 372 ARG ARG C . n 
C 1 365 ALA 365 373 373 ALA ALA C . n 
C 1 366 GLU 366 374 374 GLU GLU C . n 
C 1 367 LYS 367 375 375 LYS LYS C . n 
C 1 368 VAL 368 376 376 VAL VAL C . n 
C 1 369 LEU 369 377 377 LEU LEU C . n 
C 1 370 GLU 370 378 378 GLU GLU C . n 
C 1 371 ALA 371 379 379 ALA ALA C . n 
C 1 372 CYS 372 380 380 CYS CYS C . n 
C 1 373 SER 373 381 381 SER SER C . n 
C 1 374 ILE 374 382 382 ILE ILE C . n 
C 1 375 ALA 375 383 383 ALA ALA C . n 
C 1 376 CYS 376 384 384 CYS CYS C . n 
C 1 377 ASN 377 385 385 ASN ASN C . n 
C 1 378 LYS 378 386 386 LYS LYS C . n 
C 1 379 ASN 379 387 387 ASN ASN C . n 
C 1 380 THR 380 388 388 THR THR C . n 
C 1 381 CYS 381 389 389 CYS CYS C . n 
C 1 382 PRO 382 390 390 PRO PRO C . n 
C 1 383 GLY 383 391 391 GLY GLY C . n 
C 1 384 ASP 384 392 392 ASP ASP C . n 
C 1 385 ARG 385 393 393 ARG ARG C . n 
C 1 386 SER 386 394 394 SER SER C . n 
C 1 387 ALA 387 395 395 ALA ALA C . n 
C 1 388 LEU 388 396 396 LEU LEU C . n 
C 1 389 ARG 389 397 397 ARG ARG C . n 
C 1 390 PRO 390 398 398 PRO PRO C . n 
C 1 391 SER 391 399 399 SER SER C . n 
C 1 392 GLY 392 400 400 GLY GLY C . n 
C 1 393 LEU 393 401 401 LEU LEU C . n 
C 1 394 ARG 394 402 402 ARG ARG C . n 
C 1 395 LEU 395 403 403 LEU LEU C . n 
C 1 396 GLY 396 404 404 GLY GLY C . n 
C 1 397 THR 397 405 405 THR THR C . n 
C 1 398 PRO 398 406 406 PRO PRO C . n 
C 1 399 ALA 399 407 407 ALA ALA C . n 
C 1 400 LEU 400 408 408 LEU LEU C . n 
C 1 401 THR 401 409 409 THR THR C . n 
C 1 402 SER 402 410 410 SER SER C . n 
C 1 403 ARG 403 411 411 ARG ARG C . n 
C 1 404 GLY 404 412 412 GLY GLY C . n 
C 1 405 LEU 405 413 413 LEU LEU C . n 
C 1 406 LEU 406 414 414 LEU LEU C . n 
C 1 407 GLU 407 415 415 GLU GLU C . n 
C 1 408 LYS 408 416 416 LYS LYS C . n 
C 1 409 ASP 409 417 417 ASP ASP C . n 
C 1 410 PHE 410 418 418 PHE PHE C . n 
C 1 411 GLN 411 419 419 GLN GLN C . n 
C 1 412 LYS 412 420 420 LYS LYS C . n 
C 1 413 VAL 413 421 421 VAL VAL C . n 
C 1 414 ALA 414 422 422 ALA ALA C . n 
C 1 415 HIS 415 423 423 HIS HIS C . n 
C 1 416 PHE 416 424 424 PHE PHE C . n 
C 1 417 ILE 417 425 425 ILE ILE C . n 
C 1 418 HIS 418 426 426 HIS HIS C . n 
C 1 419 ARG 419 427 427 ARG ARG C . n 
C 1 420 GLY 420 428 428 GLY GLY C . n 
C 1 421 ILE 421 429 429 ILE ILE C . n 
C 1 422 GLU 422 430 430 GLU GLU C . n 
C 1 423 LEU 423 431 431 LEU LEU C . n 
C 1 424 THR 424 432 432 THR THR C . n 
C 1 425 LEU 425 433 433 LEU LEU C . n 
C 1 426 GLN 426 434 434 GLN GLN C . n 
C 1 427 ILE 427 435 435 ILE ILE C . n 
C 1 428 GLN 428 436 436 GLN GLN C . n 
C 1 429 SER 429 437 437 SER SER C . n 
C 1 430 ASP 430 438 438 ASP ASP C . n 
C 1 431 THR 431 439 439 THR THR C . n 
C 1 432 GLY 432 440 440 GLY GLY C . n 
C 1 433 VAL 433 441 441 VAL VAL C . n 
C 1 434 ALA 434 442 442 ALA ALA C . n 
C 1 435 ALA 435 443 443 ALA ALA C . n 
C 1 436 THR 436 444 444 THR THR C . n 
C 1 437 LEU 437 445 445 LEU LEU C . n 
C 1 438 LYS 438 446 446 LYS LYS C . n 
C 1 439 GLU 439 447 447 GLU GLU C . n 
C 1 440 PHE 440 448 448 PHE PHE C . n 
C 1 441 LYS 441 449 449 LYS LYS C . n 
C 1 442 GLU 442 450 450 GLU GLU C . n 
C 1 443 ARG 443 451 451 ARG ARG C . n 
C 1 444 LEU 444 452 452 LEU LEU C . n 
C 1 445 ALA 445 453 453 ALA ALA C . n 
C 1 446 GLY 446 454 454 GLY GLY C . n 
C 1 447 ASP 447 455 455 ASP ASP C . n 
C 1 448 LYS 448 456 456 LYS LYS C . n 
C 1 449 TYR 449 457 457 TYR TYR C . n 
C 1 450 GLN 450 458 458 GLN GLN C . n 
C 1 451 ALA 451 459 459 ALA ALA C . n 
C 1 452 ALA 452 460 460 ALA ALA C . n 
C 1 453 VAL 453 461 461 VAL VAL C . n 
C 1 454 GLN 454 462 462 GLN GLN C . n 
C 1 455 ALA 455 463 463 ALA ALA C . n 
C 1 456 LEU 456 464 464 LEU LEU C . n 
C 1 457 ARG 457 465 465 ARG ARG C . n 
C 1 458 GLU 458 466 466 GLU GLU C . n 
C 1 459 GLU 459 467 467 GLU GLU C . n 
C 1 460 VAL 460 468 468 VAL VAL C . n 
C 1 461 GLU 461 469 469 GLU GLU C . n 
C 1 462 SER 462 470 470 SER SER C . n 
C 1 463 PHE 463 471 471 PHE PHE C . n 
C 1 464 ALA 464 472 472 ALA ALA C . n 
C 1 465 SER 465 473 473 SER SER C . n 
C 1 466 LEU 466 474 474 LEU LEU C . n 
C 1 467 PHE 467 475 475 PHE PHE C . n 
C 1 468 PRO 468 476 476 PRO PRO C . n 
C 1 469 LEU 469 477 477 LEU LEU C . n 
C 1 470 PRO 470 478 478 PRO PRO C . n 
C 1 471 GLY 471 479 479 GLY GLY C . n 
C 1 472 LEU 472 480 480 LEU LEU C . n 
D 1 1   GLN 1   9   9   GLN GLN D . n 
D 1 2   GLY 2   10  10  GLY GLY D . n 
D 1 3   ASP 3   11  11  ASP ASP D . n 
D 1 4   ALA 4   12  12  ALA ALA D . n 
D 1 5   ASP 5   13  13  ASP ASP D . n 
D 1 6   LEU 6   14  14  LEU LEU D . n 
D 1 7   TRP 7   15  15  TRP TRP D . n 
D 1 8   SER 8   16  16  SER SER D . n 
D 1 9   SER 9   17  17  SER SER D . n 
D 1 10  HIS 10  18  18  HIS HIS D . n 
D 1 11  ASP 11  19  19  ASP ASP D . n 
D 1 12  ALA 12  20  20  ALA ALA D . n 
D 1 13  MET 13  21  21  MET MET D . n 
D 1 14  LEU 14  22  22  LEU LEU D . n 
D 1 15  ALA 15  23  23  ALA ALA D . n 
D 1 16  GLN 16  24  24  GLN GLN D . n 
D 1 17  PRO 17  25  25  PRO PRO D . n 
D 1 18  LEU 18  26  26  LEU LEU D . n 
D 1 19  LYS 19  27  27  LYS LYS D . n 
D 1 20  ASP 20  28  28  ASP ASP D . n 
D 1 21  SER 21  29  29  SER SER D . n 
D 1 22  ASP 22  30  30  ASP ASP D . n 
D 1 23  VAL 23  31  31  VAL VAL D . n 
D 1 24  GLU 24  32  32  GLU GLU D . n 
D 1 25  VAL 25  33  33  VAL VAL D . n 
D 1 26  TYR 26  34  34  TYR TYR D . n 
D 1 27  ASN 27  35  35  ASN ASN D . n 
D 1 28  ILE 28  36  36  ILE ILE D . n 
D 1 29  ILE 29  37  37  ILE ILE D . n 
D 1 30  LYS 30  38  38  LYS LYS D . n 
D 1 31  LYS 31  39  39  LYS LYS D . n 
D 1 32  GLU 32  40  40  GLU GLU D . n 
D 1 33  SER 33  41  41  SER SER D . n 
D 1 34  ASN 34  42  42  ASN ASN D . n 
D 1 35  ARG 35  43  43  ARG ARG D . n 
D 1 36  GLN 36  44  44  GLN GLN D . n 
D 1 37  ARG 37  45  45  ARG ARG D . n 
D 1 38  VAL 38  46  46  VAL VAL D . n 
D 1 39  GLY 39  47  47  GLY GLY D . n 
D 1 40  LEU 40  48  48  LEU LEU D . n 
D 1 41  GLU 41  49  49  GLU GLU D . n 
D 1 42  LEU 42  50  50  LEU LEU D . n 
D 1 43  ILE 43  51  51  ILE ILE D . n 
D 1 44  ALA 44  52  52  ALA ALA D . n 
D 1 45  SER 45  53  53  SER SER D . n 
D 1 46  GLU 46  54  54  GLU GLU D . n 
D 1 47  ASN 47  55  55  ASN ASN D . n 
D 1 48  PHE 48  56  56  PHE PHE D . n 
D 1 49  ALA 49  57  57  ALA ALA D . n 
D 1 50  SER 50  58  58  SER SER D . n 
D 1 51  ARG 51  59  59  ARG ARG D . n 
D 1 52  ALA 52  60  60  ALA ALA D . n 
D 1 53  VAL 53  61  61  VAL VAL D . n 
D 1 54  LEU 54  62  62  LEU LEU D . n 
D 1 55  GLU 55  63  63  GLU GLU D . n 
D 1 56  ALA 56  64  64  ALA ALA D . n 
D 1 57  LEU 57  65  65  LEU LEU D . n 
D 1 58  GLY 58  66  66  GLY GLY D . n 
D 1 59  SER 59  67  67  SER SER D . n 
D 1 60  CYS 60  68  68  CYS CYS D . n 
D 1 61  LEU 61  69  69  LEU LEU D . n 
D 1 62  ASN 62  70  70  ASN ASN D . n 
D 1 63  ASN 63  71  71  ASN ASN D . n 
D 1 64  LYS 64  72  72  LYS LYS D . n 
D 1 65  TYR 65  73  73  TYR TYR D . n 
D 1 66  SER 66  74  74  SER SER D . n 
D 1 67  GLU 67  75  75  GLU GLU D . n 
D 1 68  GLY 68  76  76  GLY GLY D . n 
D 1 69  TYR 69  77  77  TYR TYR D . n 
D 1 70  PRO 70  78  78  PRO PRO D . n 
D 1 71  GLY 71  79  79  GLY GLY D . n 
D 1 72  GLN 72  80  80  GLN GLN D . n 
D 1 73  ARG 73  81  81  ARG ARG D . n 
D 1 74  TYR 74  82  82  TYR TYR D . n 
D 1 75  TYR 75  83  83  TYR TYR D . n 
D 1 76  GLY 76  84  84  GLY GLY D . n 
D 1 77  GLY 77  85  85  GLY GLY D . n 
D 1 78  THR 78  86  86  THR THR D . n 
D 1 79  GLU 79  87  87  GLU GLU D . n 
D 1 80  PHE 80  88  88  PHE PHE D . n 
D 1 81  ILE 81  89  89  ILE ILE D . n 
D 1 82  ASP 82  90  90  ASP ASP D . n 
D 1 83  GLU 83  91  91  GLU GLU D . n 
D 1 84  LEU 84  92  92  LEU LEU D . n 
D 1 85  GLU 85  93  93  GLU GLU D . n 
D 1 86  THR 86  94  94  THR THR D . n 
D 1 87  LEU 87  95  95  LEU LEU D . n 
D 1 88  CYS 88  96  96  CYS CYS D . n 
D 1 89  GLN 89  97  97  GLN GLN D . n 
D 1 90  LYS 90  98  98  LYS LYS D . n 
D 1 91  ARG 91  99  99  ARG ARG D . n 
D 1 92  ALA 92  100 100 ALA ALA D . n 
D 1 93  LEU 93  101 101 LEU LEU D . n 
D 1 94  GLN 94  102 102 GLN GLN D . n 
D 1 95  ALA 95  103 103 ALA ALA D . n 
D 1 96  TYR 96  104 104 TYR TYR D . n 
D 1 97  LYS 97  105 105 LYS LYS D . n 
D 1 98  LEU 98  106 106 LEU LEU D . n 
D 1 99  ASP 99  107 107 ASP ASP D . n 
D 1 100 PRO 100 108 108 PRO PRO D . n 
D 1 101 GLN 101 109 109 GLN GLN D . n 
D 1 102 CYS 102 110 110 CYS CYS D . n 
D 1 103 TRP 103 111 111 TRP TRP D . n 
D 1 104 GLY 104 112 112 GLY GLY D . n 
D 1 105 VAL 105 113 113 VAL VAL D . n 
D 1 106 ASN 106 114 114 ASN ASN D . n 
D 1 107 VAL 107 115 115 VAL VAL D . n 
D 1 108 GLN 108 116 116 GLN GLN D . n 
D 1 109 PRO 109 117 117 PRO PRO D . n 
D 1 110 TYR 110 118 118 TYR TYR D . n 
D 1 111 SER 111 119 119 SER SER D . n 
D 1 112 GLY 112 120 120 GLY GLY D . n 
D 1 113 SER 113 121 121 SER SER D . n 
D 1 114 PRO 114 122 122 PRO PRO D . n 
D 1 115 ALA 115 123 123 ALA ALA D . n 
D 1 116 ASN 116 124 124 ASN ASN D . n 
D 1 117 PHE 117 125 125 PHE PHE D . n 
D 1 118 ALA 118 126 126 ALA ALA D . n 
D 1 119 VAL 119 127 127 VAL VAL D . n 
D 1 120 TYR 120 128 128 TYR TYR D . n 
D 1 121 THR 121 129 129 THR THR D . n 
D 1 122 ALA 122 130 130 ALA ALA D . n 
D 1 123 LEU 123 131 131 LEU LEU D . n 
D 1 124 VAL 124 132 132 VAL VAL D . n 
D 1 125 GLU 125 133 133 GLU GLU D . n 
D 1 126 PRO 126 134 134 PRO PRO D . n 
D 1 127 HIS 127 135 135 HIS HIS D . n 
D 1 128 GLY 128 136 136 GLY GLY D . n 
D 1 129 ARG 129 137 137 ARG ARG D . n 
D 1 130 ILE 130 138 138 ILE ILE D . n 
D 1 131 MET 131 139 139 MET MET D . n 
D 1 132 GLY 132 140 140 GLY GLY D . n 
D 1 133 LEU 133 141 141 LEU LEU D . n 
D 1 134 ASP 134 142 142 ASP ASP D . n 
D 1 135 LEU 135 143 143 LEU LEU D . n 
D 1 136 PRO 136 144 144 PRO PRO D . n 
D 1 137 ASP 137 145 145 ASP ASP D . n 
D 1 138 GLY 138 146 146 GLY GLY D . n 
D 1 139 GLY 139 147 147 GLY GLY D . n 
D 1 140 HIS 140 148 148 HIS HIS D . n 
D 1 141 LEU 141 149 149 LEU LEU D . n 
D 1 142 THR 142 150 150 THR THR D . n 
D 1 143 HIS 143 151 151 HIS HIS D . n 
D 1 144 GLY 144 152 152 GLY GLY D . n 
D 1 145 PHE 145 153 153 PHE PHE D . n 
D 1 146 MET 146 154 154 MET MET D . n 
D 1 147 THR 147 155 155 THR THR D . n 
D 1 148 ASP 148 156 156 ASP ASP D . n 
D 1 149 LYS 149 157 157 LYS LYS D . n 
D 1 150 LYS 150 158 158 LYS LYS D . n 
D 1 151 LYS 151 159 159 LYS LYS D . n 
D 1 152 ILE 152 160 160 ILE ILE D . n 
D 1 153 SER 153 161 161 SER SER D . n 
D 1 154 ALA 154 162 162 ALA ALA D . n 
D 1 155 THR 155 163 163 THR THR D . n 
D 1 156 SER 156 164 164 SER SER D . n 
D 1 157 ILE 157 165 165 ILE ILE D . n 
D 1 158 PHE 158 166 166 PHE PHE D . n 
D 1 159 PHE 159 167 167 PHE PHE D . n 
D 1 160 GLU 160 168 168 GLU GLU D . n 
D 1 161 SER 161 169 169 SER SER D . n 
D 1 162 MET 162 170 170 MET MET D . n 
D 1 163 PRO 163 171 171 PRO PRO D . n 
D 1 164 TYR 164 172 172 TYR TYR D . n 
D 1 165 LYS 165 173 173 LYS LYS D . n 
D 1 166 VAL 166 174 174 VAL VAL D . n 
D 1 167 ASN 167 175 175 ASN ASN D . n 
D 1 168 PRO 168 176 176 PRO PRO D . n 
D 1 169 ASP 169 177 177 ASP ASP D . n 
D 1 170 THR 170 178 178 THR THR D . n 
D 1 171 GLY 171 179 179 GLY GLY D . n 
D 1 172 TYR 172 180 180 TYR TYR D . n 
D 1 173 ILE 173 181 181 ILE ILE D . n 
D 1 174 ASN 174 182 182 ASN ASN D . n 
D 1 175 TYR 175 183 183 TYR TYR D . n 
D 1 176 ASP 176 184 184 ASP ASP D . n 
D 1 177 GLN 177 185 185 GLN GLN D . n 
D 1 178 LEU 178 186 186 LEU LEU D . n 
D 1 179 GLU 179 187 187 GLU GLU D . n 
D 1 180 GLU 180 188 188 GLU GLU D . n 
D 1 181 ASN 181 189 189 ASN ASN D . n 
D 1 182 ALA 182 190 190 ALA ALA D . n 
D 1 183 ARG 183 191 191 ARG ARG D . n 
D 1 184 LEU 184 192 192 LEU LEU D . n 
D 1 185 PHE 185 193 193 PHE PHE D . n 
D 1 186 HIS 186 194 194 HIS HIS D . n 
D 1 187 PRO 187 195 195 PRO PRO D . n 
D 1 188 LYS 188 196 196 LYS LYS D . n 
D 1 189 LEU 189 197 197 LEU LEU D . n 
D 1 190 ILE 190 198 198 ILE ILE D . n 
D 1 191 ILE 191 199 199 ILE ILE D . n 
D 1 192 ALA 192 200 200 ALA ALA D . n 
D 1 193 GLY 193 201 201 GLY GLY D . n 
D 1 194 THR 194 202 202 THR THR D . n 
D 1 195 SER 195 203 203 SER SER D . n 
D 1 196 CYS 196 204 204 CYS CYS D . n 
D 1 197 TYR 197 205 205 TYR TYR D . n 
D 1 198 SER 198 206 206 SER SER D . n 
D 1 199 ARG 199 207 207 ARG ARG D . n 
D 1 200 ASN 200 208 208 ASN ASN D . n 
D 1 201 LEU 201 209 209 LEU LEU D . n 
D 1 202 GLU 202 210 210 GLU GLU D . n 
D 1 203 TYR 203 211 211 TYR TYR D . n 
D 1 204 ALA 204 212 212 ALA ALA D . n 
D 1 205 ARG 205 213 213 ARG ARG D . n 
D 1 206 LEU 206 214 214 LEU LEU D . n 
D 1 207 ARG 207 215 215 ARG ARG D . n 
D 1 208 LYS 208 216 216 LYS LYS D . n 
D 1 209 ILE 209 217 217 ILE ILE D . n 
D 1 210 ALA 210 218 218 ALA ALA D . n 
D 1 211 ASP 211 219 219 ASP ASP D . n 
D 1 212 GLU 212 220 220 GLU GLU D . n 
D 1 213 ASN 213 221 221 ASN ASN D . n 
D 1 214 GLY 214 222 222 GLY GLY D . n 
D 1 215 ALA 215 223 223 ALA ALA D . n 
D 1 216 TYR 216 224 224 TYR TYR D . n 
D 1 217 LEU 217 225 225 LEU LEU D . n 
D 1 218 MET 218 226 226 MET MET D . n 
D 1 219 ALA 219 227 227 ALA ALA D . n 
D 1 220 ASP 220 228 228 ASP ASP D . n 
D 1 221 MET 221 229 229 MET MET D . n 
D 1 222 ALA 222 230 230 ALA ALA D . n 
D 1 223 HIS 223 231 231 HIS HIS D . n 
D 1 224 ILE 224 232 232 ILE ILE D . n 
D 1 225 SER 225 233 233 SER SER D . n 
D 1 226 GLY 226 234 234 GLY GLY D . n 
D 1 227 LEU 227 235 235 LEU LEU D . n 
D 1 228 VAL 228 236 236 VAL VAL D . n 
D 1 229 ALA 229 237 237 ALA ALA D . n 
D 1 230 ALA 230 238 238 ALA ALA D . n 
D 1 231 GLY 231 239 239 GLY GLY D . n 
D 1 232 VAL 232 240 240 VAL VAL D . n 
D 1 233 VAL 233 241 241 VAL VAL D . n 
D 1 234 PRO 234 242 242 PRO PRO D . n 
D 1 235 SER 235 243 243 SER SER D . n 
D 1 236 PRO 236 244 244 PRO PRO D . n 
D 1 237 PHE 237 245 245 PHE PHE D . n 
D 1 238 GLU 238 246 246 GLU GLU D . n 
D 1 239 HIS 239 247 247 HIS HIS D . n 
D 1 240 CYS 240 248 248 CYS CYS D . n 
D 1 241 HIS 241 249 249 HIS HIS D . n 
D 1 242 VAL 242 250 250 VAL VAL D . n 
D 1 243 VAL 243 251 251 VAL VAL D . n 
D 1 244 THR 244 252 252 THR THR D . n 
D 1 245 THR 245 253 253 THR THR D . n 
D 1 246 THR 246 254 254 THR THR D . n 
D 1 247 THR 247 255 255 THR THR D . n 
D 1 248 HIS 248 256 256 HIS HIS D . n 
D 1 249 LYS 249 257 257 LYS LYS D . n 
D 1 250 THR 250 258 258 THR THR D . n 
D 1 251 LEU 251 259 259 LEU LEU D . n 
D 1 252 ARG 252 260 260 ARG ARG D . n 
D 1 253 GLY 253 261 261 GLY GLY D . n 
D 1 254 CYS 254 262 262 CYS CYS D . n 
D 1 255 ARG 255 263 263 ARG ARG D . n 
D 1 256 ALA 256 264 264 ALA ALA D . n 
D 1 257 GLY 257 265 265 GLY GLY D . n 
D 1 258 MET 258 266 266 MET MET D . n 
D 1 259 ILE 259 267 267 ILE ILE D . n 
D 1 260 PHE 260 268 268 PHE PHE D . n 
D 1 261 TYR 261 269 269 TYR TYR D . n 
D 1 262 ARG 262 270 270 ARG ARG D . n 
D 1 263 LYS 263 271 271 LYS LYS D . n 
D 1 264 GLY 264 272 272 GLY GLY D . n 
D 1 265 VAL 265 273 273 VAL VAL D . n 
D 1 266 LYS 266 274 274 LYS LYS D . n 
D 1 267 SER 267 275 275 SER SER D . n 
D 1 268 VAL 268 276 276 VAL VAL D . n 
D 1 269 ASP 269 277 277 ASP ASP D . n 
D 1 270 PRO 270 278 278 PRO PRO D . n 
D 1 271 ALA 271 279 279 ALA ALA D . n 
D 1 272 THR 272 280 280 THR THR D . n 
D 1 273 GLY 273 281 281 GLY GLY D . n 
D 1 274 LYS 274 282 282 LYS LYS D . n 
D 1 275 GLU 275 283 283 GLU GLU D . n 
D 1 276 ILE 276 284 284 ILE ILE D . n 
D 1 277 LEU 277 285 285 LEU LEU D . n 
D 1 278 TYR 278 286 286 TYR TYR D . n 
D 1 279 ASN 279 287 287 ASN ASN D . n 
D 1 280 LEU 280 288 288 LEU LEU D . n 
D 1 281 GLU 281 289 289 GLU GLU D . n 
D 1 282 SER 282 290 290 SER SER D . n 
D 1 283 LEU 283 291 291 LEU LEU D . n 
D 1 284 ILE 284 292 292 ILE ILE D . n 
D 1 285 ASN 285 293 293 ASN ASN D . n 
D 1 286 SER 286 294 294 SER SER D . n 
D 1 287 ALA 287 295 295 ALA ALA D . n 
D 1 288 VAL 288 296 296 VAL VAL D . n 
D 1 289 PHE 289 297 297 PHE PHE D . n 
D 1 290 PRO 290 298 298 PRO PRO D . n 
D 1 291 GLY 291 299 299 GLY GLY D . n 
D 1 292 LEU 292 300 300 LEU LEU D . n 
D 1 293 GLN 293 301 301 GLN GLN D . n 
D 1 294 GLY 294 302 302 GLY GLY D . n 
D 1 295 GLY 295 303 303 GLY GLY D . n 
D 1 296 PRO 296 304 304 PRO PRO D . n 
D 1 297 HIS 297 305 305 HIS HIS D . n 
D 1 298 ASN 298 306 306 ASN ASN D . n 
D 1 299 HIS 299 307 307 HIS HIS D . n 
D 1 300 ALA 300 308 308 ALA ALA D . n 
D 1 301 ILE 301 309 309 ILE ILE D . n 
D 1 302 ALA 302 310 310 ALA ALA D . n 
D 1 303 GLY 303 311 311 GLY GLY D . n 
D 1 304 VAL 304 312 312 VAL VAL D . n 
D 1 305 ALA 305 313 313 ALA ALA D . n 
D 1 306 VAL 306 314 314 VAL VAL D . n 
D 1 307 ALA 307 315 315 ALA ALA D . n 
D 1 308 LEU 308 316 316 LEU LEU D . n 
D 1 309 LYS 309 317 317 LYS LYS D . n 
D 1 310 GLN 310 318 318 GLN GLN D . n 
D 1 311 ALA 311 319 319 ALA ALA D . n 
D 1 312 MET 312 320 320 MET MET D . n 
D 1 313 THR 313 321 321 THR THR D . n 
D 1 314 LEU 314 322 322 LEU LEU D . n 
D 1 315 GLU 315 323 323 GLU GLU D . n 
D 1 316 PHE 316 324 324 PHE PHE D . n 
D 1 317 LYS 317 325 325 LYS LYS D . n 
D 1 318 VAL 318 326 326 VAL VAL D . n 
D 1 319 TYR 319 327 327 TYR TYR D . n 
D 1 320 GLN 320 328 328 GLN GLN D . n 
D 1 321 HIS 321 329 329 HIS HIS D . n 
D 1 322 GLN 322 330 330 GLN GLN D . n 
D 1 323 VAL 323 331 331 VAL VAL D . n 
D 1 324 VAL 324 332 332 VAL VAL D . n 
D 1 325 ALA 325 333 333 ALA ALA D . n 
D 1 326 ASN 326 334 334 ASN ASN D . n 
D 1 327 CYS 327 335 335 CYS CYS D . n 
D 1 328 ARG 328 336 336 ARG ARG D . n 
D 1 329 ALA 329 337 337 ALA ALA D . n 
D 1 330 LEU 330 338 338 LEU LEU D . n 
D 1 331 SER 331 339 339 SER SER D . n 
D 1 332 GLU 332 340 340 GLU GLU D . n 
D 1 333 ALA 333 341 341 ALA ALA D . n 
D 1 334 LEU 334 342 342 LEU LEU D . n 
D 1 335 THR 335 343 343 THR THR D . n 
D 1 336 GLU 336 344 344 GLU GLU D . n 
D 1 337 LEU 337 345 345 LEU LEU D . n 
D 1 338 GLY 338 346 346 GLY GLY D . n 
D 1 339 TYR 339 347 347 TYR TYR D . n 
D 1 340 LYS 340 348 348 LYS LYS D . n 
D 1 341 ILE 341 349 349 ILE ILE D . n 
D 1 342 VAL 342 350 350 VAL VAL D . n 
D 1 343 THR 343 351 351 THR THR D . n 
D 1 344 GLY 344 352 352 GLY GLY D . n 
D 1 345 GLY 345 353 353 GLY GLY D . n 
D 1 346 SER 346 354 354 SER SER D . n 
D 1 347 ASP 347 355 355 ASP ASP D . n 
D 1 348 ASN 348 356 356 ASN ASN D . n 
D 1 349 HIS 349 357 357 HIS HIS D . n 
D 1 350 LEU 350 358 358 LEU LEU D . n 
D 1 351 ILE 351 359 359 ILE ILE D . n 
D 1 352 LEU 352 360 360 LEU LEU D . n 
D 1 353 VAL 353 361 361 VAL VAL D . n 
D 1 354 ASP 354 362 362 ASP ASP D . n 
D 1 355 LEU 355 363 363 LEU LEU D . n 
D 1 356 ARG 356 364 364 ARG ARG D . n 
D 1 357 SER 357 365 365 SER SER D . n 
D 1 358 LYS 358 366 366 LYS LYS D . n 
D 1 359 GLY 359 367 367 GLY GLY D . n 
D 1 360 THR 360 368 368 THR THR D . n 
D 1 361 ASP 361 369 369 ASP ASP D . n 
D 1 362 GLY 362 370 370 GLY GLY D . n 
D 1 363 GLY 363 371 371 GLY GLY D . n 
D 1 364 ARG 364 372 372 ARG ARG D . n 
D 1 365 ALA 365 373 373 ALA ALA D . n 
D 1 366 GLU 366 374 374 GLU GLU D . n 
D 1 367 LYS 367 375 375 LYS LYS D . n 
D 1 368 VAL 368 376 376 VAL VAL D . n 
D 1 369 LEU 369 377 377 LEU LEU D . n 
D 1 370 GLU 370 378 378 GLU GLU D . n 
D 1 371 ALA 371 379 379 ALA ALA D . n 
D 1 372 CYS 372 380 380 CYS CYS D . n 
D 1 373 SER 373 381 381 SER SER D . n 
D 1 374 ILE 374 382 382 ILE ILE D . n 
D 1 375 ALA 375 383 383 ALA ALA D . n 
D 1 376 CYS 376 384 384 CYS CYS D . n 
D 1 377 ASN 377 385 385 ASN ASN D . n 
D 1 378 LYS 378 386 386 LYS LYS D . n 
D 1 379 ASN 379 387 387 ASN ASN D . n 
D 1 380 THR 380 388 388 THR THR D . n 
D 1 381 CYS 381 389 389 CYS CYS D . n 
D 1 382 PRO 382 390 390 PRO PRO D . n 
D 1 383 GLY 383 391 391 GLY GLY D . n 
D 1 384 ASP 384 392 392 ASP ASP D . n 
D 1 385 ARG 385 393 393 ARG ARG D . n 
D 1 386 SER 386 394 394 SER SER D . n 
D 1 387 ALA 387 395 395 ALA ALA D . n 
D 1 388 LEU 388 396 396 LEU LEU D . n 
D 1 389 ARG 389 397 397 ARG ARG D . n 
D 1 390 PRO 390 398 398 PRO PRO D . n 
D 1 391 SER 391 399 399 SER SER D . n 
D 1 392 GLY 392 400 400 GLY GLY D . n 
D 1 393 LEU 393 401 401 LEU LEU D . n 
D 1 394 ARG 394 402 402 ARG ARG D . n 
D 1 395 LEU 395 403 403 LEU LEU D . n 
D 1 396 GLY 396 404 404 GLY GLY D . n 
D 1 397 THR 397 405 405 THR THR D . n 
D 1 398 PRO 398 406 406 PRO PRO D . n 
D 1 399 ALA 399 407 407 ALA ALA D . n 
D 1 400 LEU 400 408 408 LEU LEU D . n 
D 1 401 THR 401 409 409 THR THR D . n 
D 1 402 SER 402 410 410 SER SER D . n 
D 1 403 ARG 403 411 411 ARG ARG D . n 
D 1 404 GLY 404 412 412 GLY GLY D . n 
D 1 405 LEU 405 413 413 LEU LEU D . n 
D 1 406 LEU 406 414 414 LEU LEU D . n 
D 1 407 GLU 407 415 415 GLU GLU D . n 
D 1 408 LYS 408 416 416 LYS LYS D . n 
D 1 409 ASP 409 417 417 ASP ASP D . n 
D 1 410 PHE 410 418 418 PHE PHE D . n 
D 1 411 GLN 411 419 419 GLN GLN D . n 
D 1 412 LYS 412 420 420 LYS LYS D . n 
D 1 413 VAL 413 421 421 VAL VAL D . n 
D 1 414 ALA 414 422 422 ALA ALA D . n 
D 1 415 HIS 415 423 423 HIS HIS D . n 
D 1 416 PHE 416 424 424 PHE PHE D . n 
D 1 417 ILE 417 425 425 ILE ILE D . n 
D 1 418 HIS 418 426 426 HIS HIS D . n 
D 1 419 ARG 419 427 427 ARG ARG D . n 
D 1 420 GLY 420 428 428 GLY GLY D . n 
D 1 421 ILE 421 429 429 ILE ILE D . n 
D 1 422 GLU 422 430 430 GLU GLU D . n 
D 1 423 LEU 423 431 431 LEU LEU D . n 
D 1 424 THR 424 432 432 THR THR D . n 
D 1 425 LEU 425 433 433 LEU LEU D . n 
D 1 426 GLN 426 434 434 GLN GLN D . n 
D 1 427 ILE 427 435 435 ILE ILE D . n 
D 1 428 GLN 428 436 436 GLN GLN D . n 
D 1 429 SER 429 437 437 SER SER D . n 
D 1 430 ASP 430 438 438 ASP ASP D . n 
D 1 431 THR 431 439 439 THR THR D . n 
D 1 432 GLY 432 440 440 GLY GLY D . n 
D 1 433 VAL 433 441 441 VAL VAL D . n 
D 1 434 ALA 434 442 442 ALA ALA D . n 
D 1 435 ALA 435 443 443 ALA ALA D . n 
D 1 436 THR 436 444 444 THR THR D . n 
D 1 437 LEU 437 445 445 LEU LEU D . n 
D 1 438 LYS 438 446 446 LYS LYS D . n 
D 1 439 GLU 439 447 447 GLU GLU D . n 
D 1 440 PHE 440 448 448 PHE PHE D . n 
D 1 441 LYS 441 449 449 LYS LYS D . n 
D 1 442 GLU 442 450 450 GLU GLU D . n 
D 1 443 ARG 443 451 451 ARG ARG D . n 
D 1 444 LEU 444 452 452 LEU LEU D . n 
D 1 445 ALA 445 453 453 ALA ALA D . n 
D 1 446 GLY 446 454 454 GLY GLY D . n 
D 1 447 ASP 447 455 455 ASP ASP D . n 
D 1 448 LYS 448 456 456 LYS LYS D . n 
D 1 449 TYR 449 457 457 TYR TYR D . n 
D 1 450 GLN 450 458 458 GLN GLN D . n 
D 1 451 ALA 451 459 459 ALA ALA D . n 
D 1 452 ALA 452 460 460 ALA ALA D . n 
D 1 453 VAL 453 461 461 VAL VAL D . n 
D 1 454 GLN 454 462 462 GLN GLN D . n 
D 1 455 ALA 455 463 463 ALA ALA D . n 
D 1 456 LEU 456 464 464 LEU LEU D . n 
D 1 457 ARG 457 465 465 ARG ARG D . n 
D 1 458 GLU 458 466 466 GLU GLU D . n 
D 1 459 GLU 459 467 467 GLU GLU D . n 
D 1 460 VAL 460 468 468 VAL VAL D . n 
D 1 461 GLU 461 469 469 GLU GLU D . n 
D 1 462 SER 462 470 470 SER SER D . n 
D 1 463 PHE 463 471 471 PHE PHE D . n 
D 1 464 ALA 464 472 472 ALA ALA D . n 
D 1 465 SER 465 473 473 SER SER D . n 
D 1 466 LEU 466 474 474 LEU LEU D . n 
D 1 467 PHE 467 475 475 PHE PHE D . n 
D 1 468 PRO 468 476 476 PRO PRO D . n 
D 1 469 LEU 469 477 477 LEU LEU D . n 
D 1 470 PRO 470 478 478 PRO PRO D . n 
D 1 471 GLY 471 479 479 GLY GLY D . n 
D 1 472 LEU 472 480 480 LEU LEU D . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 PLP 1 500 500 PLP PLP A . 
F 2 PLP 1 500 500 PLP PLP B . 
G 2 PLP 1 500 500 PLP PLP C . 
H 2 PLP 1 500 500 PLP PLP D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 N 1 A PLP 500 ? O4A ? E PLP 1 O4A 
2 1 N 1 B PLP 500 ? O4A ? F PLP 1 O4A 
3 1 N 1 C PLP 500 ? O4A ? G PLP 1 O4A 
4 1 N 1 D PLP 500 ? O4A ? H PLP 1 O4A 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0419 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8XND 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     151.540 
_cell.length_a_esd                 ? 
_cell.length_b                     151.540 
_cell.length_b_esd                 ? 
_cell.length_c                     234.970 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        12 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8XND 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                145 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 32' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8XND 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             ? 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          ? 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M Sodium HEPES pH 7.5,30 %(v/v) PEG 300' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-08-27 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.18057 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'CLSI BEAMLINE 08ID-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.18057 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   08ID-1 
_diffrn_source.pdbx_synchrotron_site       CLSI 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8XND 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              3.45 
_reflns.d_resolution_low                               48.53 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     79382 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                5.3 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          10.4 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.995 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.161 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    3.45 
_reflns_shell.d_res_low                                     3.52 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4531 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.787 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            46.38 
_refine.aniso_B[1][2]                            0.00 
_refine.aniso_B[1][3]                            0.00 
_refine.aniso_B[2][2]                            46.38 
_refine.aniso_B[2][3]                            0.00 
_refine.aniso_B[3][3]                            -92.77 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               90.799 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.961 
_refine.correlation_coeff_Fo_to_Fc_free          0.944 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8XND 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.45 
_refine.ls_d_res_low                             48.53 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     75288 
_refine.ls_number_reflns_R_free                  4049 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.92 
_refine.ls_percent_reflns_R_free                 5.1 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.15499 
_refine.ls_R_factor_R_free                       0.19205 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.15300 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.106 
_refine.pdbx_overall_ESU_R_Free                  0.063 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             6.096 
_refine.overall_SU_ML                            0.107 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       3.45 
_refine_hist.d_res_low                        48.53 
_refine_hist.number_atoms_solvent             0 
_refine_hist.number_atoms_total               14588 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        14528 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         60 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.012  0.012  14885 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 2.693  1.833  20142 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.628  5.000  1884  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 15.204 5.000  92    ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 18.804 10.000 2532  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.167  0.200  2232  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.010  0.020  11232 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 15.343 9.088  7548  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 21.374 16.197 9428  ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 17.256 8.974  7337  ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 27.293 109.22 67195 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       3.450 
_refine_ls_shell.d_res_low                        3.539 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             334 
_refine_ls_shell.number_reflns_R_work             5484 
_refine_ls_shell.percent_reflns_obs               99.78 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.192 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.238 
# 
_struct.entry_id                     8XND 
_struct.title                        'Crystal structure of serine hydroxymethyltransferase 1' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8XND 
_struct_keywords.text            'methyltransferase, TRANSFERASE' 
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    GLYC_HUMAN 
_struct_ref.pdbx_db_accession          P34896 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;DADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFID
ELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESM
PYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHV
VTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQ
VVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTS
RGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
;
_struct_ref.pdbx_align_begin           11 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8XND A 3 ? 472 ? P34896 11 ? 480 ? 11 480 
2 1 8XND B 3 ? 472 ? P34896 11 ? 480 ? 11 480 
3 1 8XND C 3 ? 472 ? P34896 11 ? 480 ? 11 480 
4 1 8XND D 3 ? 472 ? P34896 11 ? 480 ? 11 480 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8XND GLN A 1   ? UNP P34896 ?   ?   'expression tag' 9   1  
1 8XND GLY A 2   ? UNP P34896 ?   ?   'expression tag' 10  2  
1 8XND ALA A 12  ? UNP P34896 LYS 20  conflict         20  3  
1 8XND ALA A 271 ? UNP P34896 LYS 279 conflict         279 4  
1 8XND ALA A 434 ? UNP P34896 ARG 442 conflict         442 5  
2 8XND GLN B 1   ? UNP P34896 ?   ?   'expression tag' 9   6  
2 8XND GLY B 2   ? UNP P34896 ?   ?   'expression tag' 10  7  
2 8XND ALA B 12  ? UNP P34896 LYS 20  conflict         20  8  
2 8XND ALA B 271 ? UNP P34896 LYS 279 conflict         279 9  
2 8XND ALA B 434 ? UNP P34896 ARG 442 conflict         442 10 
3 8XND GLN C 1   ? UNP P34896 ?   ?   'expression tag' 9   11 
3 8XND GLY C 2   ? UNP P34896 ?   ?   'expression tag' 10  12 
3 8XND ALA C 12  ? UNP P34896 LYS 20  conflict         20  13 
3 8XND ALA C 271 ? UNP P34896 LYS 279 conflict         279 14 
3 8XND ALA C 434 ? UNP P34896 ARG 442 conflict         442 15 
4 8XND GLN D 1   ? UNP P34896 ?   ?   'expression tag' 9   16 
4 8XND GLY D 2   ? UNP P34896 ?   ?   'expression tag' 10  17 
4 8XND ALA D 12  ? UNP P34896 LYS 20  conflict         20  18 
4 8XND ALA D 271 ? UNP P34896 LYS 279 conflict         279 19 
4 8XND ALA D 434 ? UNP P34896 ARG 442 conflict         442 20 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 10540 ? 
1 MORE         -68   ? 
1 'SSA (A^2)'  32750 ? 
2 'ABSA (A^2)' 10720 ? 
2 MORE         -61   ? 
2 'SSA (A^2)'  32990 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,D,E,H 
2 1 B,C,F,G 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 3   ? GLN A 16  ? ASP A 11  GLN A 24  1 ? 14 
HELX_P HELX_P2  AA2 ASP A 22  ? GLY A 39  ? ASP A 30  GLY A 47  1 ? 18 
HELX_P HELX_P3  AA3 SER A 50  ? SER A 59  ? SER A 58  SER A 67  1 ? 10 
HELX_P HELX_P4  AA4 CYS A 60  ? LYS A 64  ? CYS A 68  LYS A 72  5 ? 5  
HELX_P HELX_P5  AA5 THR A 78  ? TYR A 96  ? THR A 86  TYR A 104 1 ? 19 
HELX_P HELX_P6  AA6 SER A 111 ? VAL A 124 ? SER A 119 VAL A 132 1 ? 14 
HELX_P HELX_P7  AA7 ASP A 134 ? GLY A 138 ? ASP A 142 GLY A 146 5 ? 5  
HELX_P HELX_P8  AA8 HIS A 140 ? GLY A 144 ? HIS A 148 GLY A 152 5 ? 5  
HELX_P HELX_P9  AA9 SER A 153 ? PHE A 159 ? SER A 161 PHE A 167 1 ? 7  
HELX_P HELX_P10 AB1 ASN A 174 ? HIS A 186 ? ASN A 182 HIS A 194 1 ? 13 
HELX_P HELX_P11 AB2 GLU A 202 ? ASN A 213 ? GLU A 210 ASN A 221 1 ? 12 
HELX_P HELX_P12 AB3 ILE A 224 ? ALA A 230 ? ILE A 232 ALA A 238 1 ? 7  
HELX_P HELX_P13 AB4 SER A 235 ? HIS A 239 ? SER A 243 HIS A 247 5 ? 5  
HELX_P HELX_P14 AB5 HIS A 248 ? ARG A 252 ? HIS A 256 ARG A 260 5 ? 5  
HELX_P HELX_P15 AB6 ASN A 279 ? PHE A 289 ? ASN A 287 PHE A 297 1 ? 11 
HELX_P HELX_P16 AB7 HIS A 297 ? MET A 312 ? HIS A 305 MET A 320 1 ? 16 
HELX_P HELX_P17 AB8 THR A 313 ? LEU A 337 ? THR A 321 LEU A 345 1 ? 25 
HELX_P HELX_P18 AB9 THR A 343 ? GLY A 345 ? THR A 351 GLY A 353 5 ? 3  
HELX_P HELX_P19 AC1 ARG A 356 ? GLY A 359 ? ARG A 364 GLY A 367 5 ? 4  
HELX_P HELX_P20 AC2 ASP A 361 ? CYS A 372 ? ASP A 369 CYS A 380 1 ? 12 
HELX_P HELX_P21 AC3 THR A 397 ? SER A 402 ? THR A 405 SER A 410 1 ? 6  
HELX_P HELX_P22 AC4 LEU A 406 ? GLY A 432 ? LEU A 414 GLY A 440 1 ? 27 
HELX_P HELX_P23 AC5 THR A 436 ? GLY A 446 ? THR A 444 GLY A 454 1 ? 11 
HELX_P HELX_P24 AC6 GLY A 446 ? LEU A 466 ? GLY A 454 LEU A 474 1 ? 21 
HELX_P HELX_P25 AC7 ASP B 3   ? LEU B 14  ? ASP B 11  LEU B 22  1 ? 12 
HELX_P HELX_P26 AC8 ASP B 22  ? GLY B 39  ? ASP B 30  GLY B 47  1 ? 18 
HELX_P HELX_P27 AC9 SER B 50  ? GLY B 58  ? SER B 58  GLY B 66  1 ? 9  
HELX_P HELX_P28 AD1 SER B 59  ? LYS B 64  ? SER B 67  LYS B 72  5 ? 6  
HELX_P HELX_P29 AD2 THR B 78  ? TYR B 96  ? THR B 86  TYR B 104 1 ? 19 
HELX_P HELX_P30 AD3 SER B 111 ? VAL B 124 ? SER B 119 VAL B 132 1 ? 14 
HELX_P HELX_P31 AD4 LEU B 135 ? GLY B 138 ? LEU B 143 GLY B 146 5 ? 4  
HELX_P HELX_P32 AD5 HIS B 140 ? GLY B 144 ? HIS B 148 GLY B 152 5 ? 5  
HELX_P HELX_P33 AD6 SER B 153 ? PHE B 159 ? SER B 161 PHE B 167 1 ? 7  
HELX_P HELX_P34 AD7 ASN B 174 ? HIS B 186 ? ASN B 182 HIS B 194 1 ? 13 
HELX_P HELX_P35 AD8 GLU B 202 ? ASN B 213 ? GLU B 210 ASN B 221 1 ? 12 
HELX_P HELX_P36 AD9 ILE B 224 ? ALA B 230 ? ILE B 232 ALA B 238 1 ? 7  
HELX_P HELX_P37 AE1 SER B 235 ? HIS B 239 ? SER B 243 HIS B 247 5 ? 5  
HELX_P HELX_P38 AE2 HIS B 248 ? ARG B 252 ? HIS B 256 ARG B 260 5 ? 5  
HELX_P HELX_P39 AE3 ASN B 279 ? PHE B 289 ? ASN B 287 PHE B 297 1 ? 11 
HELX_P HELX_P40 AE4 HIS B 297 ? MET B 312 ? HIS B 305 MET B 320 1 ? 16 
HELX_P HELX_P41 AE5 THR B 313 ? LEU B 337 ? THR B 321 LEU B 345 1 ? 25 
HELX_P HELX_P42 AE6 THR B 343 ? GLY B 345 ? THR B 351 GLY B 353 5 ? 3  
HELX_P HELX_P43 AE7 ARG B 356 ? GLY B 359 ? ARG B 364 GLY B 367 5 ? 4  
HELX_P HELX_P44 AE8 ASP B 361 ? CYS B 372 ? ASP B 369 CYS B 380 1 ? 12 
HELX_P HELX_P45 AE9 THR B 397 ? SER B 402 ? THR B 405 SER B 410 1 ? 6  
HELX_P HELX_P46 AF1 LEU B 406 ? GLY B 432 ? LEU B 414 GLY B 440 1 ? 27 
HELX_P HELX_P47 AF2 THR B 436 ? GLY B 446 ? THR B 444 GLY B 454 1 ? 11 
HELX_P HELX_P48 AF3 GLY B 446 ? LEU B 466 ? GLY B 454 LEU B 474 1 ? 21 
HELX_P HELX_P49 AF4 ASP C 3   ? LEU C 14  ? ASP C 11  LEU C 22  1 ? 12 
HELX_P HELX_P50 AF5 ASP C 22  ? GLY C 39  ? ASP C 30  GLY C 47  1 ? 18 
HELX_P HELX_P51 AF6 SER C 50  ? SER C 59  ? SER C 58  SER C 67  1 ? 10 
HELX_P HELX_P52 AF7 CYS C 60  ? LYS C 64  ? CYS C 68  LYS C 72  5 ? 5  
HELX_P HELX_P53 AF8 THR C 78  ? TYR C 96  ? THR C 86  TYR C 104 1 ? 19 
HELX_P HELX_P54 AF9 SER C 111 ? VAL C 124 ? SER C 119 VAL C 132 1 ? 14 
HELX_P HELX_P55 AG1 LEU C 135 ? GLY C 138 ? LEU C 143 GLY C 146 5 ? 4  
HELX_P HELX_P56 AG2 HIS C 140 ? GLY C 144 ? HIS C 148 GLY C 152 5 ? 5  
HELX_P HELX_P57 AG3 SER C 153 ? PHE C 159 ? SER C 161 PHE C 167 1 ? 7  
HELX_P HELX_P58 AG4 ASN C 174 ? HIS C 186 ? ASN C 182 HIS C 194 1 ? 13 
HELX_P HELX_P59 AG5 GLU C 202 ? ASN C 213 ? GLU C 210 ASN C 221 1 ? 12 
HELX_P HELX_P60 AG6 ILE C 224 ? ALA C 230 ? ILE C 232 ALA C 238 1 ? 7  
HELX_P HELX_P61 AG7 SER C 235 ? HIS C 239 ? SER C 243 HIS C 247 5 ? 5  
HELX_P HELX_P62 AG8 HIS C 248 ? ARG C 252 ? HIS C 256 ARG C 260 5 ? 5  
HELX_P HELX_P63 AG9 ASN C 279 ? PHE C 289 ? ASN C 287 PHE C 297 1 ? 11 
HELX_P HELX_P64 AH1 HIS C 297 ? MET C 312 ? HIS C 305 MET C 320 1 ? 16 
HELX_P HELX_P65 AH2 THR C 313 ? LEU C 337 ? THR C 321 LEU C 345 1 ? 25 
HELX_P HELX_P66 AH3 THR C 343 ? GLY C 345 ? THR C 351 GLY C 353 5 ? 3  
HELX_P HELX_P67 AH4 ARG C 356 ? GLY C 359 ? ARG C 364 GLY C 367 5 ? 4  
HELX_P HELX_P68 AH5 ASP C 361 ? CYS C 372 ? ASP C 369 CYS C 380 1 ? 12 
HELX_P HELX_P69 AH6 THR C 397 ? SER C 402 ? THR C 405 SER C 410 1 ? 6  
HELX_P HELX_P70 AH7 LEU C 406 ? GLY C 432 ? LEU C 414 GLY C 440 1 ? 27 
HELX_P HELX_P71 AH8 THR C 436 ? GLY C 446 ? THR C 444 GLY C 454 1 ? 11 
HELX_P HELX_P72 AH9 GLY C 446 ? LEU C 466 ? GLY C 454 LEU C 474 1 ? 21 
HELX_P HELX_P73 AI1 ASP D 3   ? GLN D 16  ? ASP D 11  GLN D 24  1 ? 14 
HELX_P HELX_P74 AI2 ASP D 22  ? GLY D 39  ? ASP D 30  GLY D 47  1 ? 18 
HELX_P HELX_P75 AI3 SER D 50  ? GLY D 58  ? SER D 58  GLY D 66  1 ? 9  
HELX_P HELX_P76 AI4 SER D 59  ? ASN D 63  ? SER D 67  ASN D 71  5 ? 5  
HELX_P HELX_P77 AI5 THR D 78  ? TYR D 96  ? THR D 86  TYR D 104 1 ? 19 
HELX_P HELX_P78 AI6 SER D 111 ? VAL D 124 ? SER D 119 VAL D 132 1 ? 14 
HELX_P HELX_P79 AI7 LEU D 135 ? GLY D 138 ? LEU D 143 GLY D 146 5 ? 4  
HELX_P HELX_P80 AI8 HIS D 140 ? GLY D 144 ? HIS D 148 GLY D 152 5 ? 5  
HELX_P HELX_P81 AI9 SER D 153 ? PHE D 159 ? SER D 161 PHE D 167 1 ? 7  
HELX_P HELX_P82 AJ1 ASN D 174 ? HIS D 186 ? ASN D 182 HIS D 194 1 ? 13 
HELX_P HELX_P83 AJ2 GLU D 202 ? ASN D 213 ? GLU D 210 ASN D 221 1 ? 12 
HELX_P HELX_P84 AJ3 ILE D 224 ? ALA D 230 ? ILE D 232 ALA D 238 1 ? 7  
HELX_P HELX_P85 AJ4 SER D 235 ? HIS D 239 ? SER D 243 HIS D 247 5 ? 5  
HELX_P HELX_P86 AJ5 HIS D 248 ? ARG D 252 ? HIS D 256 ARG D 260 5 ? 5  
HELX_P HELX_P87 AJ6 ASN D 279 ? PHE D 289 ? ASN D 287 PHE D 297 1 ? 11 
HELX_P HELX_P88 AJ7 HIS D 297 ? MET D 312 ? HIS D 305 MET D 320 1 ? 16 
HELX_P HELX_P89 AJ8 THR D 313 ? LEU D 337 ? THR D 321 LEU D 345 1 ? 25 
HELX_P HELX_P90 AJ9 THR D 343 ? GLY D 345 ? THR D 351 GLY D 353 5 ? 3  
HELX_P HELX_P91 AK1 ARG D 356 ? GLY D 359 ? ARG D 364 GLY D 367 5 ? 4  
HELX_P HELX_P92 AK2 ASP D 361 ? CYS D 372 ? ASP D 369 CYS D 380 1 ? 12 
HELX_P HELX_P93 AK3 THR D 397 ? SER D 402 ? THR D 405 SER D 410 1 ? 6  
HELX_P HELX_P94 AK4 LEU D 406 ? GLY D 432 ? LEU D 414 GLY D 440 1 ? 27 
HELX_P HELX_P95 AK5 THR D 436 ? GLY D 446 ? THR D 444 GLY D 454 1 ? 11 
HELX_P HELX_P96 AK6 GLY D 446 ? SER D 465 ? GLY D 454 SER D 473 1 ? 20 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 289 A . ? PHE 297 A PRO 290 A ? PRO 298 A 1 3.03 
2 PHE 289 B . ? PHE 297 B PRO 290 B ? PRO 298 B 1 3.20 
3 PHE 289 C . ? PHE 297 C PRO 290 C ? PRO 298 C 1 5.12 
4 PHE 289 D . ? PHE 297 D PRO 290 D ? PRO 298 D 1 3.32 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 7 ? 
AA4 ? 2 ? 
AA5 ? 4 ? 
AA6 ? 2 ? 
AA7 ? 2 ? 
AA8 ? 7 ? 
AA9 ? 2 ? 
AB1 ? 4 ? 
AB2 ? 2 ? 
AB3 ? 2 ? 
AB4 ? 7 ? 
AB5 ? 2 ? 
AB6 ? 4 ? 
AB7 ? 2 ? 
AB8 ? 2 ? 
AB9 ? 7 ? 
AC1 ? 2 ? 
AC2 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
AA3 5 6 ? parallel      
AA3 6 7 ? parallel      
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? parallel      
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? parallel      
AA8 4 5 ? parallel      
AA8 5 6 ? parallel      
AA8 6 7 ? parallel      
AA9 1 2 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? parallel      
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? parallel      
AB4 4 5 ? parallel      
AB4 5 6 ? parallel      
AB4 6 7 ? parallel      
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? parallel      
AB8 1 2 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? parallel      
AB9 4 5 ? parallel      
AB9 5 6 ? parallel      
AB9 6 7 ? parallel      
AC1 1 2 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 40  ? GLU A 41  ? LEU A 48  GLU A 49  
AA1 2 ILE A 374 ? ALA A 375 ? ILE A 382 ALA A 383 
AA2 1 GLY A 68  ? TYR A 69  ? GLY A 76  TYR A 77  
AA2 2 GLN A 72  ? ARG A 73  ? GLN A 80  ARG A 81  
AA3 1 TRP A 103 ? ASN A 106 ? TRP A 111 ASN A 114 
AA3 2 GLY A 257 ? ARG A 262 ? GLY A 265 ARG A 270 
AA3 3 VAL A 242 ? THR A 246 ? VAL A 250 THR A 254 
AA3 4 TYR A 216 ? ASP A 220 ? TYR A 224 ASP A 228 
AA3 5 LEU A 189 ? GLY A 193 ? LEU A 197 GLY A 201 
AA3 6 ARG A 129 ? MET A 131 ? ARG A 137 MET A 139 
AA3 7 GLU A 160 ? SER A 161 ? GLU A 168 SER A 169 
AA4 1 VAL A 265 ? VAL A 268 ? VAL A 273 VAL A 276 
AA4 2 GLU A 275 ? LEU A 277 ? GLU A 283 LEU A 285 
AA5 1 LYS A 340 ? ILE A 341 ? LYS A 348 ILE A 349 
AA5 2 LEU A 350 ? ASP A 354 ? LEU A 358 ASP A 362 
AA5 3 GLY A 392 ? GLY A 396 ? GLY A 400 GLY A 404 
AA5 4 ASN A 377 ? ASN A 379 ? ASN A 385 ASN A 387 
AA6 1 LEU B 40  ? GLU B 41  ? LEU B 48  GLU B 49  
AA6 2 ILE B 374 ? ALA B 375 ? ILE B 382 ALA B 383 
AA7 1 GLY B 68  ? TYR B 69  ? GLY B 76  TYR B 77  
AA7 2 GLN B 72  ? ARG B 73  ? GLN B 80  ARG B 81  
AA8 1 TRP B 103 ? ASN B 106 ? TRP B 111 ASN B 114 
AA8 2 GLY B 257 ? ARG B 262 ? GLY B 265 ARG B 270 
AA8 3 VAL B 242 ? THR B 246 ? VAL B 250 THR B 254 
AA8 4 TYR B 216 ? ASP B 220 ? TYR B 224 ASP B 228 
AA8 5 LEU B 189 ? ALA B 192 ? LEU B 197 ALA B 200 
AA8 6 ARG B 129 ? LEU B 133 ? ARG B 137 LEU B 141 
AA8 7 GLU B 160 ? TYR B 164 ? GLU B 168 TYR B 172 
AA9 1 VAL B 265 ? VAL B 268 ? VAL B 273 VAL B 276 
AA9 2 GLU B 275 ? LEU B 277 ? GLU B 283 LEU B 285 
AB1 1 LYS B 340 ? ILE B 341 ? LYS B 348 ILE B 349 
AB1 2 LEU B 350 ? ASP B 354 ? LEU B 358 ASP B 362 
AB1 3 GLY B 392 ? GLY B 396 ? GLY B 400 GLY B 404 
AB1 4 ASN B 377 ? ASN B 379 ? ASN B 385 ASN B 387 
AB2 1 LEU C 40  ? GLU C 41  ? LEU C 48  GLU C 49  
AB2 2 ILE C 374 ? ALA C 375 ? ILE C 382 ALA C 383 
AB3 1 GLY C 68  ? TYR C 69  ? GLY C 76  TYR C 77  
AB3 2 GLN C 72  ? ARG C 73  ? GLN C 80  ARG C 81  
AB4 1 TRP C 103 ? ASN C 106 ? TRP C 111 ASN C 114 
AB4 2 GLY C 257 ? ARG C 262 ? GLY C 265 ARG C 270 
AB4 3 VAL C 242 ? THR C 246 ? VAL C 250 THR C 254 
AB4 4 TYR C 216 ? ASP C 220 ? TYR C 224 ASP C 228 
AB4 5 LEU C 189 ? GLY C 193 ? LEU C 197 GLY C 201 
AB4 6 ARG C 129 ? LEU C 133 ? ARG C 137 LEU C 141 
AB4 7 GLU C 160 ? TYR C 164 ? GLU C 168 TYR C 172 
AB5 1 GLY C 264 ? SER C 267 ? GLY C 272 SER C 275 
AB5 2 ILE C 276 ? TYR C 278 ? ILE C 284 TYR C 286 
AB6 1 LYS C 340 ? ILE C 341 ? LYS C 348 ILE C 349 
AB6 2 LEU C 350 ? ASP C 354 ? LEU C 358 ASP C 362 
AB6 3 GLY C 392 ? GLY C 396 ? GLY C 400 GLY C 404 
AB6 4 ASN C 377 ? ASN C 379 ? ASN C 385 ASN C 387 
AB7 1 LEU D 40  ? GLU D 41  ? LEU D 48  GLU D 49  
AB7 2 ILE D 374 ? ALA D 375 ? ILE D 382 ALA D 383 
AB8 1 GLY D 68  ? TYR D 69  ? GLY D 76  TYR D 77  
AB8 2 GLN D 72  ? ARG D 73  ? GLN D 80  ARG D 81  
AB9 1 TRP D 103 ? ASN D 106 ? TRP D 111 ASN D 114 
AB9 2 GLY D 257 ? ARG D 262 ? GLY D 265 ARG D 270 
AB9 3 VAL D 242 ? THR D 246 ? VAL D 250 THR D 254 
AB9 4 TYR D 216 ? ASP D 220 ? TYR D 224 ASP D 228 
AB9 5 LEU D 189 ? GLY D 193 ? LEU D 197 GLY D 201 
AB9 6 ARG D 129 ? LEU D 133 ? ARG D 137 LEU D 141 
AB9 7 GLU D 160 ? TYR D 164 ? GLU D 168 TYR D 172 
AC1 1 VAL D 265 ? VAL D 268 ? VAL D 273 VAL D 276 
AC1 2 GLU D 275 ? LEU D 277 ? GLU D 283 LEU D 285 
AC2 1 LYS D 340 ? ILE D 341 ? LYS D 348 ILE D 349 
AC2 2 LEU D 350 ? ASP D 354 ? LEU D 358 ASP D 362 
AC2 3 GLY D 392 ? GLY D 396 ? GLY D 400 GLY D 404 
AC2 4 ASN D 377 ? ASN D 379 ? ASN D 385 ASN D 387 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LEU A 40  ? N LEU A 48  O ALA A 375 ? O ALA A 383 
AA2 1 2 N TYR A 69  ? N TYR A 77  O GLN A 72  ? O GLN A 80  
AA3 1 2 N GLY A 104 ? N GLY A 112 O TYR A 261 ? O TYR A 269 
AA3 2 3 O PHE A 260 ? O PHE A 268 N VAL A 243 ? N VAL A 251 
AA3 3 4 O THR A 244 ? O THR A 252 N ALA A 219 ? N ALA A 227 
AA3 4 5 O MET A 218 ? O MET A 226 N ALA A 192 ? N ALA A 200 
AA3 5 6 O ILE A 191 ? O ILE A 199 N MET A 131 ? N MET A 139 
AA3 6 7 N ILE A 130 ? N ILE A 138 O GLU A 160 ? O GLU A 168 
AA4 1 2 N LYS A 266 ? N LYS A 274 O ILE A 276 ? O ILE A 284 
AA5 1 2 N LYS A 340 ? N LYS A 348 O ASP A 354 ? O ASP A 362 
AA5 2 3 N VAL A 353 ? N VAL A 361 O LEU A 393 ? O LEU A 401 
AA5 3 4 O ARG A 394 ? O ARG A 402 N ASN A 377 ? N ASN A 385 
AA6 1 2 N LEU B 40  ? N LEU B 48  O ALA B 375 ? O ALA B 383 
AA7 1 2 N TYR B 69  ? N TYR B 77  O GLN B 72  ? O GLN B 80  
AA8 1 2 N GLY B 104 ? N GLY B 112 O TYR B 261 ? O TYR B 269 
AA8 2 3 O PHE B 260 ? O PHE B 268 N VAL B 243 ? N VAL B 251 
AA8 3 4 O THR B 244 ? O THR B 252 N ALA B 219 ? N ALA B 227 
AA8 4 5 O MET B 218 ? O MET B 226 N ALA B 192 ? N ALA B 200 
AA8 5 6 O ILE B 191 ? O ILE B 199 N MET B 131 ? N MET B 139 
AA8 6 7 N ILE B 130 ? N ILE B 138 O GLU B 160 ? O GLU B 168 
AA9 1 2 N SER B 267 ? N SER B 275 O ILE B 276 ? O ILE B 284 
AB1 1 2 N LYS B 340 ? N LYS B 348 O ASP B 354 ? O ASP B 362 
AB1 2 3 N VAL B 353 ? N VAL B 361 O LEU B 393 ? O LEU B 401 
AB1 3 4 O ARG B 394 ? O ARG B 402 N ASN B 377 ? N ASN B 385 
AB2 1 2 N LEU C 40  ? N LEU C 48  O ALA C 375 ? O ALA C 383 
AB3 1 2 N TYR C 69  ? N TYR C 77  O GLN C 72  ? O GLN C 80  
AB4 1 2 N GLY C 104 ? N GLY C 112 O TYR C 261 ? O TYR C 269 
AB4 2 3 O PHE C 260 ? O PHE C 268 N VAL C 243 ? N VAL C 251 
AB4 3 4 O THR C 244 ? O THR C 252 N ALA C 219 ? N ALA C 227 
AB4 4 5 O MET C 218 ? O MET C 226 N ALA C 192 ? N ALA C 200 
AB4 5 6 O ILE C 191 ? O ILE C 199 N MET C 131 ? N MET C 139 
AB4 6 7 N ILE C 130 ? N ILE C 138 O GLU C 160 ? O GLU C 168 
AB5 1 2 N SER C 267 ? N SER C 275 O ILE C 276 ? O ILE C 284 
AB6 1 2 N LYS C 340 ? N LYS C 348 O ASP C 354 ? O ASP C 362 
AB6 2 3 N VAL C 353 ? N VAL C 361 O LEU C 393 ? O LEU C 401 
AB6 3 4 O ARG C 394 ? O ARG C 402 N ASN C 377 ? N ASN C 385 
AB7 1 2 N LEU D 40  ? N LEU D 48  O ALA D 375 ? O ALA D 383 
AB8 1 2 N TYR D 69  ? N TYR D 77  O GLN D 72  ? O GLN D 80  
AB9 1 2 N GLY D 104 ? N GLY D 112 O TYR D 261 ? O TYR D 269 
AB9 2 3 O PHE D 260 ? O PHE D 268 N VAL D 243 ? N VAL D 251 
AB9 3 4 O THR D 244 ? O THR D 252 N ALA D 219 ? N ALA D 227 
AB9 4 5 O MET D 218 ? O MET D 226 N ALA D 192 ? N ALA D 200 
AB9 5 6 O ILE D 191 ? O ILE D 199 N MET D 131 ? N MET D 139 
AB9 6 7 N ILE D 130 ? N ILE D 138 O GLU D 160 ? O GLU D 168 
AC1 1 2 N SER D 267 ? N SER D 275 O ILE D 276 ? O ILE D 284 
AC2 1 2 N LYS D 340 ? N LYS D 348 O ASP D 354 ? O ASP D 362 
AC2 2 3 N VAL D 353 ? N VAL D 361 O LEU D 393 ? O LEU D 401 
AC2 3 4 O ARG D 394 ? O ARG D 402 N ASN D 377 ? N ASN D 385 
# 
_pdbx_entry_details.entry_id                   8XND 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 NZ  A LYS 257 ? ? C4A A PLP 500 ? ? 1.29 
2  1 NZ  D LYS 257 ? ? C4A D PLP 500 ? ? 1.80 
3  1 OD2 B ASP 438 ? ? OH  B TYR 457 ? ? 1.96 
4  1 OE1 B GLU 54  ? ? O   C ASN 71  ? ? 1.97 
5  1 O   B SER 290 ? ? OG  B SER 294 ? ? 1.99 
6  1 O   A ASN 71  ? ? OE1 D GLU 54  ? ? 2.12 
7  1 NH1 B ARG 99  ? ? OD2 C ASP 30  ? ? 2.16 
8  1 OE2 B GLU 54  ? ? N   C TYR 73  ? ? 2.17 
9  1 OG  D SER 58  ? ? OE1 D GLN 318 ? ? 2.17 
10 1 OH  C TYR 77  ? ? O   C ASN 293 ? ? 2.18 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 CD A GLU 168 ? ? OE2 A GLU 168 ? ? 1.328 1.252 0.076 0.011 N 
2 1 CD D GLU 378 ? ? OE1 D GLU 378 ? ? 1.323 1.252 0.071 0.011 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1   1 CB  A LEU 14  ? ? CG A LEU 14  ? ? CD1 A LEU 14  ? ? 121.38 111.00 10.38  1.70 N 
2   1 CB  A LYS 27  ? ? CG A LYS 27  ? ? CD  A LYS 27  ? ? 131.53 111.60 19.93  2.60 N 
3   1 CG  A LYS 27  ? ? CD A LYS 27  ? ? CE  A LYS 27  ? ? 131.37 111.90 19.47  3.00 N 
4   1 CB  A ASN 35  ? ? CA A ASN 35  ? ? C   A ASN 35  ? ? 97.76  110.40 -12.64 2.00 N 
5   1 NE  A ARG 43  ? ? CZ A ARG 43  ? ? NH2 A ARG 43  ? ? 125.90 120.30 5.60   0.50 N 
6   1 CB  A GLU 49  ? ? CG A GLU 49  ? ? CD  A GLU 49  ? ? 97.98  114.20 -16.22 2.70 N 
7   1 CB  A ARG 59  ? ? CA A ARG 59  ? ? C   A ARG 59  ? ? 78.88  110.40 -31.52 2.00 N 
8   1 N   A ARG 59  ? ? CA A ARG 59  ? ? CB  A ARG 59  ? ? 126.06 110.60 15.46  1.80 N 
9   1 NE  A ARG 59  ? ? CZ A ARG 59  ? ? NH1 A ARG 59  ? ? 117.23 120.30 -3.07  0.50 N 
10  1 CB  A LYS 105 ? ? CG A LYS 105 ? ? CD  A LYS 105 ? ? 127.55 111.60 15.95  2.60 N 
11  1 CB  A ASN 114 ? ? CA A ASN 114 ? ? C   A ASN 114 ? ? 123.72 110.40 13.32  2.00 N 
12  1 CB  A ARG 137 ? ? CG A ARG 137 ? ? CD  A ARG 137 ? ? 128.16 111.60 16.56  2.60 N 
13  1 NE  A ARG 137 ? ? CZ A ARG 137 ? ? NH1 A ARG 137 ? ? 115.29 120.30 -5.01  0.50 N 
14  1 CB  A LEU 149 ? ? CG A LEU 149 ? ? CD1 A LEU 149 ? ? 97.56  111.00 -13.44 1.70 N 
15  1 CG  A MET 154 ? ? SD A MET 154 ? ? CE  A MET 154 ? ? 89.49  100.20 -10.71 1.60 N 
16  1 NE  A ARG 191 ? ? CZ A ARG 191 ? ? NH1 A ARG 191 ? ? 116.13 120.30 -4.17  0.50 N 
17  1 CA  A LYS 196 ? ? CB A LYS 196 ? ? CG  A LYS 196 ? ? 132.48 113.40 19.08  2.20 N 
18  1 CB  A LYS 196 ? ? CG A LYS 196 ? ? CD  A LYS 196 ? ? 130.71 111.60 19.11  2.60 N 
19  1 NE  A ARG 207 ? ? CZ A ARG 207 ? ? NH2 A ARG 207 ? ? 116.40 120.30 -3.90  0.50 N 
20  1 N   A ALA 212 ? ? CA A ALA 212 ? ? CB  A ALA 212 ? ? 98.69  110.10 -11.41 1.40 N 
21  1 NE  A ARG 213 ? ? CZ A ARG 213 ? ? NH2 A ARG 213 ? ? 117.06 120.30 -3.24  0.50 N 
22  1 CA  A ARG 215 ? ? CB A ARG 215 ? ? CG  A ARG 215 ? ? 96.60  113.40 -16.80 2.20 N 
23  1 N   A LYS 216 ? ? CA A LYS 216 ? ? CB  A LYS 216 ? ? 124.22 110.60 13.62  1.80 N 
24  1 CG  A LYS 216 ? ? CD A LYS 216 ? ? CE  A LYS 216 ? ? 130.76 111.90 18.86  3.00 N 
25  1 CD  A LYS 216 ? ? CE A LYS 216 ? ? NZ  A LYS 216 ? ? 130.31 111.70 18.61  2.30 N 
26  1 NE  A ARG 260 ? ? CZ A ARG 260 ? ? NH2 A ARG 260 ? ? 116.15 120.30 -4.15  0.50 N 
27  1 NE  A ARG 263 ? ? CZ A ARG 263 ? ? NH2 A ARG 263 ? ? 116.85 120.30 -3.45  0.50 N 
28  1 CG  A MET 266 ? ? SD A MET 266 ? ? CE  A MET 266 ? ? 110.24 100.20 10.04  1.60 N 
29  1 CB  A ARG 270 ? ? CG A ARG 270 ? ? CD  A ARG 270 ? ? 129.25 111.60 17.65  2.60 N 
30  1 CG  A LYS 348 ? ? CD A LYS 348 ? ? CE  A LYS 348 ? ? 134.35 111.90 22.45  3.00 N 
31  1 NE  A ARG 364 ? ? CZ A ARG 364 ? ? NH1 A ARG 364 ? ? 123.56 120.30 3.26   0.50 N 
32  1 CG  A ARG 372 ? ? CD A ARG 372 ? ? NE  A ARG 372 ? ? 98.35  111.80 -13.45 2.10 N 
33  1 NE  A ARG 397 ? ? CZ A ARG 397 ? ? NH1 A ARG 397 ? ? 117.23 120.30 -3.07  0.50 N 
34  1 CB  A LEU 414 ? ? CG A LEU 414 ? ? CD1 A LEU 414 ? ? 97.53  111.00 -13.47 1.70 N 
35  1 CB  A LEU 414 ? ? CG A LEU 414 ? ? CD2 A LEU 414 ? ? 123.29 111.00 12.29  1.70 N 
36  1 N   A GLU 415 ? ? CA A GLU 415 ? ? CB  A GLU 415 ? ? 122.53 110.60 11.93  1.80 N 
37  1 CG  A ARG 427 ? ? CD A ARG 427 ? ? NE  A ARG 427 ? ? 98.43  111.80 -13.37 2.10 N 
38  1 CA  A THR 432 ? ? CB A THR 432 ? ? OG1 A THR 432 ? ? 94.02  109.00 -14.98 2.10 N 
39  1 CB  B ASP 19  ? ? CA B ASP 19  ? ? C   B ASP 19  ? ? 97.24  110.40 -13.16 2.00 N 
40  1 CB  B LYS 38  ? ? CG B LYS 38  ? ? CD  B LYS 38  ? ? 133.01 111.60 21.41  2.60 N 
41  1 CB  B LYS 157 ? ? CG B LYS 157 ? ? CD  B LYS 157 ? ? 131.89 111.60 20.29  2.60 N 
42  1 CD  B LYS 157 ? ? CE B LYS 157 ? ? NZ  B LYS 157 ? ? 130.41 111.70 18.71  2.30 N 
43  1 CB  B LEU 192 ? ? CG B LEU 192 ? ? CD2 B LEU 192 ? ? 100.48 111.00 -10.52 1.70 N 
44  1 CA  B LYS 196 ? ? CB B LYS 196 ? ? CG  B LYS 196 ? ? 133.24 113.40 19.84  2.20 N 
45  1 CB  B LYS 196 ? ? CG B LYS 196 ? ? CD  B LYS 196 ? ? 133.62 111.60 22.02  2.60 N 
46  1 CD  B LYS 196 ? ? CE B LYS 196 ? ? NZ  B LYS 196 ? ? 130.66 111.70 18.96  2.30 N 
47  1 N   B ALA 212 ? ? CA B ALA 212 ? ? CB  B ALA 212 ? ? 98.43  110.10 -11.67 1.40 N 
48  1 CB  B LYS 216 ? ? CA B LYS 216 ? ? C   B LYS 216 ? ? 126.29 110.40 15.89  2.00 N 
49  1 CB  B LEU 225 ? ? CG B LEU 225 ? ? CD1 B LEU 225 ? ? 99.28  111.00 -11.72 1.70 N 
50  1 CG  B MET 226 ? ? SD B MET 226 ? ? CE  B MET 226 ? ? 86.63  100.20 -13.57 1.60 N 
51  1 NE  B ARG 260 ? ? CZ B ARG 260 ? ? NH2 B ARG 260 ? ? 117.04 120.30 -3.26  0.50 N 
52  1 NE  B ARG 263 ? ? CZ B ARG 263 ? ? NH2 B ARG 263 ? ? 114.67 120.30 -5.63  0.50 N 
53  1 CB  B ARG 270 ? ? CA B ARG 270 ? ? C   B ARG 270 ? ? 128.43 110.40 18.03  2.00 N 
54  1 NE  B ARG 270 ? ? CZ B ARG 270 ? ? NH1 B ARG 270 ? ? 124.13 120.30 3.83   0.50 N 
55  1 CB  B LYS 271 ? ? CG B LYS 271 ? ? CD  B LYS 271 ? ? 130.35 111.60 18.75  2.60 N 
56  1 CG  B LYS 271 ? ? CD B LYS 271 ? ? CE  B LYS 271 ? ? 133.63 111.90 21.73  3.00 N 
57  1 N   B PRO 298 ? ? CA B PRO 298 ? ? CB  B PRO 298 ? ? 95.18  102.60 -7.42  1.10 N 
58  1 CB  B LEU 322 ? ? CG B LEU 322 ? ? CD1 B LEU 322 ? ? 122.44 111.00 11.44  1.70 N 
59  1 CB  B ARG 393 ? ? CA B ARG 393 ? ? C   B ARG 393 ? ? 124.85 110.40 14.45  2.00 N 
60  1 CB  B LEU 414 ? ? CG B LEU 414 ? ? CD1 B LEU 414 ? ? 99.86  111.00 -11.14 1.70 N 
61  1 CB  B LEU 414 ? ? CG B LEU 414 ? ? CD2 B LEU 414 ? ? 123.19 111.00 12.19  1.70 N 
62  1 N   B GLU 415 ? ? CA B GLU 415 ? ? CB  B GLU 415 ? ? 128.81 110.60 18.21  1.80 N 
63  1 NE  B ARG 427 ? ? CZ B ARG 427 ? ? NH2 B ARG 427 ? ? 115.56 120.30 -4.74  0.50 N 
64  1 CA  B THR 432 ? ? CB B THR 432 ? ? OG1 B THR 432 ? ? 92.69  109.00 -16.31 2.10 N 
65  1 CA  B THR 439 ? ? CB B THR 439 ? ? OG1 B THR 439 ? ? 86.60  109.00 -22.40 2.10 N 
66  1 CB  C LEU 26  ? ? CG C LEU 26  ? ? CD2 C LEU 26  ? ? 122.58 111.00 11.58  1.70 N 
67  1 NE  C ARG 43  ? ? CZ C ARG 43  ? ? NH2 C ARG 43  ? ? 124.44 120.30 4.14   0.50 N 
68  1 CD  C LYS 72  ? ? CE C LYS 72  ? ? NZ  C LYS 72  ? ? 126.66 111.70 14.96  2.30 N 
69  1 NE  C ARG 81  ? ? CZ C ARG 81  ? ? NH2 C ARG 81  ? ? 116.40 120.30 -3.90  0.50 N 
70  1 OG1 C THR 94  ? ? CB C THR 94  ? ? CG2 C THR 94  ? ? 89.28  110.00 -20.72 2.30 N 
71  1 NE  C ARG 137 ? ? CZ C ARG 137 ? ? NH1 C ARG 137 ? ? 115.48 120.30 -4.82  0.50 N 
72  1 NE  C ARG 137 ? ? CZ C ARG 137 ? ? NH2 C ARG 137 ? ? 123.60 120.30 3.30   0.50 N 
73  1 N   C LYS 158 ? ? CA C LYS 158 ? ? CB  C LYS 158 ? ? 126.15 110.60 15.55  1.80 N 
74  1 CB  C LYS 158 ? ? CG C LYS 158 ? ? CD  C LYS 158 ? ? 127.35 111.60 15.75  2.60 N 
75  1 CB  C ASN 175 ? ? CA C ASN 175 ? ? C   C ASN 175 ? ? 96.98  110.40 -13.42 2.00 N 
76  1 CB  C GLU 188 ? ? CA C GLU 188 ? ? C   C GLU 188 ? ? 98.01  110.40 -12.39 2.00 N 
77  1 N   C GLU 188 ? ? CA C GLU 188 ? ? CB  C GLU 188 ? ? 133.06 110.60 22.46  1.80 N 
78  1 N   C ALA 212 ? ? CA C ALA 212 ? ? CB  C ALA 212 ? ? 99.02  110.10 -11.08 1.40 N 
79  1 CG  C ARG 215 ? ? CD C ARG 215 ? ? NE  C ARG 215 ? ? 96.88  111.80 -14.92 2.10 N 
80  1 CG  C LYS 216 ? ? CD C LYS 216 ? ? CE  C LYS 216 ? ? 132.58 111.90 20.68  3.00 N 
81  1 NE  C ARG 260 ? ? CZ C ARG 260 ? ? NH2 C ARG 260 ? ? 116.63 120.30 -3.67  0.50 N 
82  1 N   C PRO 298 ? ? CA C PRO 298 ? ? CB  C PRO 298 ? ? 94.73  102.60 -7.87  1.10 N 
83  1 CB  C LEU 338 ? ? CG C LEU 338 ? ? CD1 C LEU 338 ? ? 98.63  111.00 -12.37 1.70 N 
84  1 NE  C ARG 364 ? ? CZ C ARG 364 ? ? NH1 C ARG 364 ? ? 123.31 120.30 3.01   0.50 N 
85  1 CB  C ASN 387 ? ? CA C ASN 387 ? ? C   C ASN 387 ? ? 124.02 110.40 13.62  2.00 N 
86  1 CB  C ARG 393 ? ? CA C ARG 393 ? ? C   C ARG 393 ? ? 123.79 110.40 13.39  2.00 N 
87  1 CG  C ARG 393 ? ? CD C ARG 393 ? ? NE  C ARG 393 ? ? 127.26 111.80 15.46  2.10 N 
88  1 NE  C ARG 393 ? ? CZ C ARG 393 ? ? NH1 C ARG 393 ? ? 123.50 120.30 3.20   0.50 N 
89  1 N   C GLU 415 ? ? CA C GLU 415 ? ? CB  C GLU 415 ? ? 126.72 110.60 16.12  1.80 N 
90  1 CG  C GLU 415 ? ? CD C GLU 415 ? ? OE2 C GLU 415 ? ? 105.47 118.30 -12.83 2.00 N 
91  1 NE  C ARG 427 ? ? CZ C ARG 427 ? ? NH2 C ARG 427 ? ? 116.51 120.30 -3.79  0.50 N 
92  1 CA  C THR 432 ? ? CB C THR 432 ? ? OG1 C THR 432 ? ? 92.23  109.00 -16.77 2.10 N 
93  1 CA  C THR 439 ? ? CB C THR 439 ? ? OG1 C THR 439 ? ? 93.82  109.00 -15.18 2.10 N 
94  1 CD  C LYS 449 ? ? CE C LYS 449 ? ? NZ  C LYS 449 ? ? 125.94 111.70 14.24  2.30 N 
95  1 CB  C LEU 452 ? ? CG C LEU 452 ? ? CD2 C LEU 452 ? ? 121.29 111.00 10.29  1.70 N 
96  1 CG  D MET 21  ? ? SD D MET 21  ? ? CE  D MET 21  ? ? 113.55 100.20 13.35  1.60 N 
97  1 CB  D ASP 30  ? ? CG D ASP 30  ? ? OD2 D ASP 30  ? ? 112.36 118.30 -5.94  0.90 N 
98  1 CD  D LYS 38  ? ? CE D LYS 38  ? ? NZ  D LYS 38  ? ? 126.57 111.70 14.87  2.30 N 
99  1 NE  D ARG 43  ? ? CZ D ARG 43  ? ? NH2 D ARG 43  ? ? 124.33 120.30 4.03   0.50 N 
100 1 CB  D ARG 59  ? ? CA D ARG 59  ? ? C   D ARG 59  ? ? 82.32  110.40 -28.08 2.00 N 
101 1 N   D ARG 59  ? ? CA D ARG 59  ? ? CB  D ARG 59  ? ? 123.77 110.60 13.17  1.80 N 
102 1 OG1 D THR 94  ? ? CB D THR 94  ? ? CG2 D THR 94  ? ? 89.89  110.00 -20.11 2.30 N 
103 1 CG  D LYS 105 ? ? CD D LYS 105 ? ? CE  D LYS 105 ? ? 132.71 111.90 20.81  3.00 N 
104 1 CD  D LYS 105 ? ? CE D LYS 105 ? ? NZ  D LYS 105 ? ? 128.27 111.70 16.57  2.30 N 
105 1 CB  D HIS 135 ? ? CA D HIS 135 ? ? C   D HIS 135 ? ? 122.58 110.40 12.18  2.00 N 
106 1 NE  D ARG 137 ? ? CZ D ARG 137 ? ? NH2 D ARG 137 ? ? 124.22 120.30 3.92   0.50 N 
107 1 CB  D LEU 143 ? ? CG D LEU 143 ? ? CD2 D LEU 143 ? ? 90.60  111.00 -20.40 1.70 N 
108 1 CB  D LEU 149 ? ? CG D LEU 149 ? ? CD2 D LEU 149 ? ? 96.73  111.00 -14.27 1.70 N 
109 1 CB  D LYS 158 ? ? CG D LYS 158 ? ? CD  D LYS 158 ? ? 128.19 111.60 16.59  2.60 N 
110 1 CG  D MET 170 ? ? SD D MET 170 ? ? CE  D MET 170 ? ? 88.69  100.20 -11.51 1.60 N 
111 1 CA  D LYS 196 ? ? CB D LYS 196 ? ? CG  D LYS 196 ? ? 127.40 113.40 14.00  2.20 N 
112 1 NE  D ARG 207 ? ? CZ D ARG 207 ? ? NH2 D ARG 207 ? ? 116.61 120.30 -3.69  0.50 N 
113 1 CA  D ARG 215 ? ? CB D ARG 215 ? ? CG  D ARG 215 ? ? 90.16  113.40 -23.24 2.20 N 
114 1 CG  D ARG 215 ? ? CD D ARG 215 ? ? NE  D ARG 215 ? ? 127.06 111.80 15.26  2.10 N 
115 1 CD  D ARG 215 ? ? NE D ARG 215 ? ? CZ  D ARG 215 ? ? 110.14 123.60 -13.46 1.40 N 
116 1 NH1 D ARG 215 ? ? CZ D ARG 215 ? ? NH2 D ARG 215 ? ? 127.71 119.40 8.31   1.10 N 
117 1 NE  D ARG 215 ? ? CZ D ARG 215 ? ? NH1 D ARG 215 ? ? 113.57 120.30 -6.73  0.50 N 
118 1 N   D THR 254 ? ? CA D THR 254 ? ? CB  D THR 254 ? ? 98.88  110.30 -11.42 1.90 N 
119 1 OG1 D THR 254 ? ? CB D THR 254 ? ? CG2 D THR 254 ? ? 124.21 110.00 14.21  2.30 N 
120 1 CG  D MET 266 ? ? SD D MET 266 ? ? CE  D MET 266 ? ? 111.44 100.20 11.24  1.60 N 
121 1 CB  D ARG 270 ? ? CG D ARG 270 ? ? CD  D ARG 270 ? ? 137.28 111.60 25.68  2.60 N 
122 1 CB  D LEU 322 ? ? CG D LEU 322 ? ? CD2 D LEU 322 ? ? 100.28 111.00 -10.72 1.70 N 
123 1 OE1 D GLU 378 ? ? CD D GLU 378 ? ? OE2 D GLU 378 ? ? 130.50 123.30 7.20   1.20 N 
124 1 CG  D GLU 378 ? ? CD D GLU 378 ? ? OE2 D GLU 378 ? ? 104.61 118.30 -13.69 2.00 N 
125 1 CB  D ARG 393 ? ? CA D ARG 393 ? ? C   D ARG 393 ? ? 129.00 110.40 18.60  2.00 N 
126 1 CG  D ARG 393 ? ? CD D ARG 393 ? ? NE  D ARG 393 ? ? 125.38 111.80 13.58  2.10 N 
127 1 CB  D LEU 414 ? ? CG D LEU 414 ? ? CD2 D LEU 414 ? ? 122.31 111.00 11.31  1.70 N 
128 1 N   D GLU 415 ? ? CA D GLU 415 ? ? CB  D GLU 415 ? ? 123.93 110.60 13.33  1.80 N 
129 1 CA  D THR 432 ? ? CB D THR 432 ? ? OG1 D THR 432 ? ? 92.76  109.00 -16.24 2.10 N 
130 1 CB  D GLU 466 ? ? CG D GLU 466 ? ? CD  D GLU 466 ? ? 89.66  114.20 -24.54 2.70 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 30  ? ? 71.87   72.28   
2  1 GLN A 80  ? ? -151.28 55.33   
3  1 SER A 119 ? ? -161.20 -167.75 
4  1 GLU A 133 ? ? 62.50   152.72  
5  1 HIS A 135 ? ? 79.82   -0.38   
6  1 THR A 150 ? ? -58.77  -8.58   
7  1 PHE A 153 ? ? -171.05 119.26  
8  1 CYS A 204 ? ? -155.40 82.29   
9  1 GLU A 210 ? ? -69.04  71.15   
10 1 ALA A 212 ? ? -21.88  -70.32  
11 1 HIS A 256 ? ? -90.51  -142.58 
12 1 LYS A 257 ? ? 51.83   -133.90 
13 1 LYS A 282 ? ? -85.39  -146.66 
14 1 PRO A 298 ? ? -92.03  40.40   
15 1 THR A 351 ? ? 74.50   -5.16   
16 1 ASN A 356 ? ? -136.13 -148.47 
17 1 LEU A 363 ? ? -57.24  -2.02   
18 1 LYS A 386 ? ? -68.60  -170.20 
19 1 ASN A 387 ? ? 163.86  134.03  
20 1 LEU A 414 ? ? -116.95 -168.88 
21 1 ALA A 442 ? ? -117.93 -150.70 
22 1 ALA A 443 ? ? 94.94   130.45  
23 1 ASP B 30  ? ? 72.72   76.19   
24 1 SER B 119 ? ? -161.65 -167.32 
25 1 GLU B 133 ? ? 66.60   149.24  
26 1 THR B 150 ? ? -59.34  -9.12   
27 1 PHE B 153 ? ? -170.09 120.82  
28 1 HIS B 194 ? ? 52.75   70.68   
29 1 CYS B 204 ? ? -153.98 81.61   
30 1 ALA B 212 ? ? -20.86  -71.35  
31 1 HIS B 256 ? ? -90.97  -144.48 
32 1 LYS B 257 ? ? 53.86   -133.83 
33 1 SER B 275 ? ? 174.41  171.54  
34 1 TYR B 286 ? ? -30.02  125.56  
35 1 PRO B 298 ? ? -88.31  38.79   
36 1 THR B 351 ? ? 75.34   -4.86   
37 1 ASN B 356 ? ? -136.41 -148.03 
38 1 LYS B 386 ? ? -67.58  -171.31 
39 1 ASN B 387 ? ? 165.97  131.46  
40 1 ASP B 392 ? ? 11.53   131.92  
41 1 ARG B 393 ? ? -28.67  -79.86  
42 1 LEU B 414 ? ? -118.51 -169.82 
43 1 VAL B 441 ? ? -27.53  -75.44  
44 1 ALA B 443 ? ? -177.49 146.03  
45 1 ASP C 30  ? ? 69.40   71.85   
46 1 SER C 119 ? ? -161.04 -169.68 
47 1 GLU C 133 ? ? 61.87   160.87  
48 1 HIS C 135 ? ? 76.00   -1.16   
49 1 PHE C 153 ? ? -170.78 121.93  
50 1 ASP C 177 ? ? -78.43  -88.84  
51 1 THR C 178 ? ? -22.18  -45.21  
52 1 CYS C 204 ? ? -154.72 82.99   
53 1 GLU C 210 ? ? -66.46  68.23   
54 1 ALA C 212 ? ? -21.04  -69.88  
55 1 HIS C 256 ? ? -89.10  -144.16 
56 1 LYS C 257 ? ? 52.57   -132.95 
57 1 ALA C 264 ? ? -170.20 -179.62 
58 1 ASP C 277 ? ? -27.33  98.71   
59 1 PRO C 298 ? ? -90.68  36.83   
60 1 THR C 351 ? ? 76.49   -6.26   
61 1 ASN C 356 ? ? -138.48 -148.05 
62 1 LYS C 386 ? ? -69.58  -177.53 
63 1 ASN C 387 ? ? 163.71  147.17  
64 1 VAL C 441 ? ? -64.45  -99.02  
65 1 LEU C 445 ? ? -49.02  -17.31  
66 1 ASP D 11  ? ? 9.25    63.43   
67 1 ASP D 30  ? ? 56.28   76.42   
68 1 GLU D 133 ? ? 65.26   159.14  
69 1 THR D 150 ? ? -59.37  -7.95   
70 1 PHE D 153 ? ? -171.86 129.11  
71 1 ASP D 177 ? ? -81.16  -88.01  
72 1 THR D 178 ? ? -39.42  -35.55  
73 1 HIS D 194 ? ? 50.41   71.51   
74 1 CYS D 204 ? ? -152.72 88.16   
75 1 GLU D 210 ? ? -69.26  66.79   
76 1 HIS D 256 ? ? -88.15  -145.71 
77 1 LYS D 257 ? ? 53.98   -133.59 
78 1 PRO D 298 ? ? -93.15  42.22   
79 1 THR D 351 ? ? 75.74   -5.56   
80 1 ASN D 356 ? ? -136.60 -148.74 
81 1 LEU D 363 ? ? -59.21  -6.96   
82 1 ASN D 387 ? ? 178.15  126.88  
83 1 ARG D 393 ? ? -75.94  -83.74  
84 1 ARG D 397 ? ? -118.23 76.82   
85 1 LEU D 414 ? ? -120.94 -169.26 
86 1 ALA D 442 ? ? -155.90 53.47   
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1  1 ARG A 215 ? ? 0.206 'SIDE CHAIN' 
2  1 ARG A 263 ? ? 0.125 'SIDE CHAIN' 
3  1 ARG A 372 ? ? 0.099 'SIDE CHAIN' 
4  1 ARG A 393 ? ? 0.099 'SIDE CHAIN' 
5  1 ARG A 397 ? ? 0.124 'SIDE CHAIN' 
6  1 ARG A 427 ? ? 0.117 'SIDE CHAIN' 
7  1 ARG A 465 ? ? 0.137 'SIDE CHAIN' 
8  1 ARG B 137 ? ? 0.223 'SIDE CHAIN' 
9  1 ARG B 215 ? ? 0.094 'SIDE CHAIN' 
10 1 ARG B 372 ? ? 0.087 'SIDE CHAIN' 
11 1 ARG B 393 ? ? 0.090 'SIDE CHAIN' 
12 1 ARG B 397 ? ? 0.114 'SIDE CHAIN' 
13 1 ARG B 465 ? ? 0.117 'SIDE CHAIN' 
14 1 ARG C 45  ? ? 0.087 'SIDE CHAIN' 
15 1 ARG C 137 ? ? 0.181 'SIDE CHAIN' 
16 1 ARG C 215 ? ? 0.180 'SIDE CHAIN' 
17 1 ARG C 263 ? ? 0.093 'SIDE CHAIN' 
18 1 ARG C 465 ? ? 0.130 'SIDE CHAIN' 
19 1 ARG D 45  ? ? 0.097 'SIDE CHAIN' 
20 1 ARG D 59  ? ? 0.099 'SIDE CHAIN' 
21 1 ARG D 137 ? ? 0.138 'SIDE CHAIN' 
22 1 ARG D 215 ? ? 0.337 'SIDE CHAIN' 
23 1 ARG D 336 ? ? 0.089 'SIDE CHAIN' 
24 1 ARG D 372 ? ? 0.075 'SIDE CHAIN' 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PLP N1   N Y N 270 
PLP C2   C Y N 271 
PLP C2A  C N N 272 
PLP C3   C Y N 273 
PLP O3   O N N 274 
PLP C4   C Y N 275 
PLP C4A  C N N 276 
PLP O4A  O N N 277 
PLP C5   C Y N 278 
PLP C6   C Y N 279 
PLP C5A  C N N 280 
PLP O4P  O N N 281 
PLP P    P N N 282 
PLP O1P  O N N 283 
PLP O2P  O N N 284 
PLP O3P  O N N 285 
PLP H2A1 H N N 286 
PLP H2A2 H N N 287 
PLP H2A3 H N N 288 
PLP HO3  H N N 289 
PLP H4A  H N N 290 
PLP H6   H N N 291 
PLP H5A1 H N N 292 
PLP H5A2 H N N 293 
PLP HOP2 H N N 294 
PLP HOP3 H N N 295 
PRO N    N N N 296 
PRO CA   C N S 297 
PRO C    C N N 298 
PRO O    O N N 299 
PRO CB   C N N 300 
PRO CG   C N N 301 
PRO CD   C N N 302 
PRO OXT  O N N 303 
PRO H    H N N 304 
PRO HA   H N N 305 
PRO HB2  H N N 306 
PRO HB3  H N N 307 
PRO HG2  H N N 308 
PRO HG3  H N N 309 
PRO HD2  H N N 310 
PRO HD3  H N N 311 
PRO HXT  H N N 312 
SER N    N N N 313 
SER CA   C N S 314 
SER C    C N N 315 
SER O    O N N 316 
SER CB   C N N 317 
SER OG   O N N 318 
SER OXT  O N N 319 
SER H    H N N 320 
SER H2   H N N 321 
SER HA   H N N 322 
SER HB2  H N N 323 
SER HB3  H N N 324 
SER HG   H N N 325 
SER HXT  H N N 326 
THR N    N N N 327 
THR CA   C N S 328 
THR C    C N N 329 
THR O    O N N 330 
THR CB   C N R 331 
THR OG1  O N N 332 
THR CG2  C N N 333 
THR OXT  O N N 334 
THR H    H N N 335 
THR H2   H N N 336 
THR HA   H N N 337 
THR HB   H N N 338 
THR HG1  H N N 339 
THR HG21 H N N 340 
THR HG22 H N N 341 
THR HG23 H N N 342 
THR HXT  H N N 343 
TRP N    N N N 344 
TRP CA   C N S 345 
TRP C    C N N 346 
TRP O    O N N 347 
TRP CB   C N N 348 
TRP CG   C Y N 349 
TRP CD1  C Y N 350 
TRP CD2  C Y N 351 
TRP NE1  N Y N 352 
TRP CE2  C Y N 353 
TRP CE3  C Y N 354 
TRP CZ2  C Y N 355 
TRP CZ3  C Y N 356 
TRP CH2  C Y N 357 
TRP OXT  O N N 358 
TRP H    H N N 359 
TRP H2   H N N 360 
TRP HA   H N N 361 
TRP HB2  H N N 362 
TRP HB3  H N N 363 
TRP HD1  H N N 364 
TRP HE1  H N N 365 
TRP HE3  H N N 366 
TRP HZ2  H N N 367 
TRP HZ3  H N N 368 
TRP HH2  H N N 369 
TRP HXT  H N N 370 
TYR N    N N N 371 
TYR CA   C N S 372 
TYR C    C N N 373 
TYR O    O N N 374 
TYR CB   C N N 375 
TYR CG   C Y N 376 
TYR CD1  C Y N 377 
TYR CD2  C Y N 378 
TYR CE1  C Y N 379 
TYR CE2  C Y N 380 
TYR CZ   C Y N 381 
TYR OH   O N N 382 
TYR OXT  O N N 383 
TYR H    H N N 384 
TYR H2   H N N 385 
TYR HA   H N N 386 
TYR HB2  H N N 387 
TYR HB3  H N N 388 
TYR HD1  H N N 389 
TYR HD2  H N N 390 
TYR HE1  H N N 391 
TYR HE2  H N N 392 
TYR HH   H N N 393 
TYR HXT  H N N 394 
VAL N    N N N 395 
VAL CA   C N S 396 
VAL C    C N N 397 
VAL O    O N N 398 
VAL CB   C N N 399 
VAL CG1  C N N 400 
VAL CG2  C N N 401 
VAL OXT  O N N 402 
VAL H    H N N 403 
VAL H2   H N N 404 
VAL HA   H N N 405 
VAL HB   H N N 406 
VAL HG11 H N N 407 
VAL HG12 H N N 408 
VAL HG13 H N N 409 
VAL HG21 H N N 410 
VAL HG22 H N N 411 
VAL HG23 H N N 412 
VAL HXT  H N N 413 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PLP N1  C2   doub Y N 258 
PLP N1  C6   sing Y N 259 
PLP C2  C2A  sing N N 260 
PLP C2  C3   sing Y N 261 
PLP C2A H2A1 sing N N 262 
PLP C2A H2A2 sing N N 263 
PLP C2A H2A3 sing N N 264 
PLP C3  O3   sing N N 265 
PLP C3  C4   doub Y N 266 
PLP O3  HO3  sing N N 267 
PLP C4  C4A  sing N N 268 
PLP C4  C5   sing Y N 269 
PLP C4A O4A  doub N N 270 
PLP C4A H4A  sing N N 271 
PLP C5  C6   doub Y N 272 
PLP C5  C5A  sing N N 273 
PLP C6  H6   sing N N 274 
PLP C5A O4P  sing N N 275 
PLP C5A H5A1 sing N N 276 
PLP C5A H5A2 sing N N 277 
PLP O4P P    sing N N 278 
PLP P   O1P  doub N N 279 
PLP P   O2P  sing N N 280 
PLP P   O3P  sing N N 281 
PLP O2P HOP2 sing N N 282 
PLP O3P HOP3 sing N N 283 
PRO N   CA   sing N N 284 
PRO N   CD   sing N N 285 
PRO N   H    sing N N 286 
PRO CA  C    sing N N 287 
PRO CA  CB   sing N N 288 
PRO CA  HA   sing N N 289 
PRO C   O    doub N N 290 
PRO C   OXT  sing N N 291 
PRO CB  CG   sing N N 292 
PRO CB  HB2  sing N N 293 
PRO CB  HB3  sing N N 294 
PRO CG  CD   sing N N 295 
PRO CG  HG2  sing N N 296 
PRO CG  HG3  sing N N 297 
PRO CD  HD2  sing N N 298 
PRO CD  HD3  sing N N 299 
PRO OXT HXT  sing N N 300 
SER N   CA   sing N N 301 
SER N   H    sing N N 302 
SER N   H2   sing N N 303 
SER CA  C    sing N N 304 
SER CA  CB   sing N N 305 
SER CA  HA   sing N N 306 
SER C   O    doub N N 307 
SER C   OXT  sing N N 308 
SER CB  OG   sing N N 309 
SER CB  HB2  sing N N 310 
SER CB  HB3  sing N N 311 
SER OG  HG   sing N N 312 
SER OXT HXT  sing N N 313 
THR N   CA   sing N N 314 
THR N   H    sing N N 315 
THR N   H2   sing N N 316 
THR CA  C    sing N N 317 
THR CA  CB   sing N N 318 
THR CA  HA   sing N N 319 
THR C   O    doub N N 320 
THR C   OXT  sing N N 321 
THR CB  OG1  sing N N 322 
THR CB  CG2  sing N N 323 
THR CB  HB   sing N N 324 
THR OG1 HG1  sing N N 325 
THR CG2 HG21 sing N N 326 
THR CG2 HG22 sing N N 327 
THR CG2 HG23 sing N N 328 
THR OXT HXT  sing N N 329 
TRP N   CA   sing N N 330 
TRP N   H    sing N N 331 
TRP N   H2   sing N N 332 
TRP CA  C    sing N N 333 
TRP CA  CB   sing N N 334 
TRP CA  HA   sing N N 335 
TRP C   O    doub N N 336 
TRP C   OXT  sing N N 337 
TRP CB  CG   sing N N 338 
TRP CB  HB2  sing N N 339 
TRP CB  HB3  sing N N 340 
TRP CG  CD1  doub Y N 341 
TRP CG  CD2  sing Y N 342 
TRP CD1 NE1  sing Y N 343 
TRP CD1 HD1  sing N N 344 
TRP CD2 CE2  doub Y N 345 
TRP CD2 CE3  sing Y N 346 
TRP NE1 CE2  sing Y N 347 
TRP NE1 HE1  sing N N 348 
TRP CE2 CZ2  sing Y N 349 
TRP CE3 CZ3  doub Y N 350 
TRP CE3 HE3  sing N N 351 
TRP CZ2 CH2  doub Y N 352 
TRP CZ2 HZ2  sing N N 353 
TRP CZ3 CH2  sing Y N 354 
TRP CZ3 HZ3  sing N N 355 
TRP CH2 HH2  sing N N 356 
TRP OXT HXT  sing N N 357 
TYR N   CA   sing N N 358 
TYR N   H    sing N N 359 
TYR N   H2   sing N N 360 
TYR CA  C    sing N N 361 
TYR CA  CB   sing N N 362 
TYR CA  HA   sing N N 363 
TYR C   O    doub N N 364 
TYR C   OXT  sing N N 365 
TYR CB  CG   sing N N 366 
TYR CB  HB2  sing N N 367 
TYR CB  HB3  sing N N 368 
TYR CG  CD1  doub Y N 369 
TYR CG  CD2  sing Y N 370 
TYR CD1 CE1  sing Y N 371 
TYR CD1 HD1  sing N N 372 
TYR CD2 CE2  doub Y N 373 
TYR CD2 HD2  sing N N 374 
TYR CE1 CZ   doub Y N 375 
TYR CE1 HE1  sing N N 376 
TYR CE2 CZ   sing Y N 377 
TYR CE2 HE2  sing N N 378 
TYR CZ  OH   sing N N 379 
TYR OH  HH   sing N N 380 
TYR OXT HXT  sing N N 381 
VAL N   CA   sing N N 382 
VAL N   H    sing N N 383 
VAL N   H2   sing N N 384 
VAL CA  C    sing N N 385 
VAL CA  CB   sing N N 386 
VAL CA  HA   sing N N 387 
VAL C   O    doub N N 388 
VAL C   OXT  sing N N 389 
VAL CB  CG1  sing N N 390 
VAL CB  CG2  sing N N 391 
VAL CB  HB   sing N N 392 
VAL CG1 HG11 sing N N 393 
VAL CG1 HG12 sing N N 394 
VAL CG1 HG13 sing N N 395 
VAL CG2 HG21 sing N N 396 
VAL CG2 HG22 sing N N 397 
VAL CG2 HG23 sing N N 398 
VAL OXT HXT  sing N N 399 
# 
_pdbx_audit_support.funding_organization   'Other government' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           2018YFA0901800 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   1BJ4 
_pdbx_initial_refinement_model.details          ? 
# 
loop_
_pdbx_reflns_twin.domain_id 
_pdbx_reflns_twin.crystal_id 
_pdbx_reflns_twin.diffrn_id 
_pdbx_reflns_twin.type 
_pdbx_reflns_twin.operator 
_pdbx_reflns_twin.fraction 
1 1 1 ? 'H, K, L'    0.228 
2 1 1 ? 'K, H, -L'   0.231 
3 1 1 ? -h,-k,l      0.240 
4 1 1 ? '-K, -H, -L' 0.301 
# 
_atom_sites.entry_id                    8XND 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.006599 
_atom_sites.fract_transf_matrix[1][2]   0.003810 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   -0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007620 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   -0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.004256 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . GLN A 1 1   ? -0.139  94.333  8.640  1.00 91.02  ? 9   GLN A N   1 
ATOM   2     C CA  . GLN A 1 1   ? -1.519  94.635  8.176  1.00 128.33 ? 9   GLN A CA  1 
ATOM   3     C C   . GLN A 1 1   ? -1.559  96.083  7.679  1.00 160.59 ? 9   GLN A C   1 
ATOM   4     O O   . GLN A 1 1   ? -0.641  96.841  8.026  1.00 145.76 ? 9   GLN A O   1 
ATOM   5     C CB  . GLN A 1 1   ? -2.525  94.381  9.301  1.00 30.00  ? 9   GLN A CB  1 
ATOM   6     C CG  . GLN A 1 1   ? -2.767  95.587  10.193 1.00 30.00  ? 9   GLN A CG  1 
ATOM   7     C CD  . GLN A 1 1   ? -4.188  96.068  10.058 1.00 30.00  ? 9   GLN A CD  1 
ATOM   8     O OE1 . GLN A 1 1   ? -4.476  97.256  10.173 1.00 30.00  ? 9   GLN A OE1 1 
ATOM   9     N NE2 . GLN A 1 1   ? -5.091  95.137  9.799  1.00 30.00  ? 9   GLN A NE2 1 
ATOM   10    N N   . GLY A 1 2   ? -2.571  96.436  6.884  1.00 146.98 ? 10  GLY A N   1 
ATOM   11    C CA  . GLY A 1 2   ? -2.714  97.822  6.410  1.00 94.94  ? 10  GLY A CA  1 
ATOM   12    C C   . GLY A 1 2   ? -1.942  98.773  7.297  1.00 100.60 ? 10  GLY A C   1 
ATOM   13    O O   . GLY A 1 2   ? -0.941  99.330  6.823  1.00 112.12 ? 10  GLY A O   1 
ATOM   14    N N   . ASP A 1 3   ? -2.382  98.939  8.546  1.00 121.06 ? 11  ASP A N   1 
ATOM   15    C CA  . ASP A 1 3   ? -1.653  99.815  9.498  1.00 120.75 ? 11  ASP A CA  1 
ATOM   16    C C   . ASP A 1 3   ? -0.709  98.949  10.319 1.00 133.65 ? 11  ASP A C   1 
ATOM   17    O O   . ASP A 1 3   ? -1.002  98.711  11.498 1.00 171.01 ? 11  ASP A O   1 
ATOM   18    C CB  . ASP A 1 3   ? -2.595  100.604 10.405 1.00 102.88 ? 11  ASP A CB  1 
ATOM   19    C CG  . ASP A 1 3   ? -1.888  101.681 11.210 1.00 129.63 ? 11  ASP A CG  1 
ATOM   20    O OD1 . ASP A 1 3   ? -0.647  101.618 11.319 1.00 113.85 ? 11  ASP A OD1 1 
ATOM   21    O OD2 . ASP A 1 3   ? -2.583  102.576 11.725 1.00 168.23 ? 11  ASP A OD2 1 
ATOM   22    N N   . ALA A 1 4   ? 0.374   98.492  9.701  1.00 115.23 ? 12  ALA A N   1 
ATOM   23    C CA  . ALA A 1 4   ? 1.371   97.704  10.447 1.00 136.69 ? 12  ALA A CA  1 
ATOM   24    C C   . ALA A 1 4   ? 1.517   98.313  11.832 1.00 139.41 ? 12  ALA A C   1 
ATOM   25    O O   . ALA A 1 4   ? 1.318   97.607  12.829 1.00 114.61 ? 12  ALA A O   1 
ATOM   26    C CB  . ALA A 1 4   ? 2.679   97.752  9.722  1.00 119.25 ? 12  ALA A CB  1 
ATOM   27    N N   . ASP A 1 5   ? 1.865   99.592  11.867 1.00 129.58 ? 13  ASP A N   1 
ATOM   28    C CA  . ASP A 1 5   ? 2.049   100.266 13.169 1.00 134.12 ? 13  ASP A CA  1 
ATOM   29    C C   . ASP A 1 5   ? 0.880   99.881  14.072 1.00 141.79 ? 13  ASP A C   1 
ATOM   30    O O   . ASP A 1 5   ? 1.138   99.450  15.206 1.00 112.62 ? 13  ASP A O   1 
ATOM   31    C CB  . ASP A 1 5   ? 2.203   101.773 12.980 1.00 136.26 ? 13  ASP A CB  1 
ATOM   32    C CG  . ASP A 1 5   ? 3.103   102.126 11.811 1.00 137.01 ? 13  ASP A CG  1 
ATOM   33    O OD1 . ASP A 1 5   ? 4.328   102.205 12.021 1.00 96.23  ? 13  ASP A OD1 1 
ATOM   34    O OD2 . ASP A 1 5   ? 2.571   102.309 10.699 1.00 133.41 ? 13  ASP A OD2 1 
ATOM   35    N N   . LEU A 1 6   ? -0.359  99.996  13.590 1.00 132.50 ? 14  LEU A N   1 
ATOM   36    C CA  . LEU A 1 6   ? -1.434  99.692  14.533 1.00 80.58  ? 14  LEU A CA  1 
ATOM   37    C C   . LEU A 1 6   ? -1.256  98.273  15.060 1.00 75.80  ? 14  LEU A C   1 
ATOM   38    O O   . LEU A 1 6   ? -1.341  98.067  16.274 1.00 91.99  ? 14  LEU A O   1 
ATOM   39    C CB  . LEU A 1 6   ? -2.779  99.868  13.851 1.00 66.31  ? 14  LEU A CB  1 
ATOM   40    C CG  . LEU A 1 6   ? -4.030  99.723  14.724 1.00 88.82  ? 14  LEU A CG  1 
ATOM   41    C CD1 . LEU A 1 6   ? -4.059  100.240 16.184 1.00 69.59  ? 14  LEU A CD1 1 
ATOM   42    C CD2 . LEU A 1 6   ? -5.224  100.313 13.940 1.00 82.36  ? 14  LEU A CD2 1 
ATOM   43    N N   . TRP A 1 7   ? -0.942  97.328  14.159 1.00 88.15  ? 15  TRP A N   1 
ATOM   44    C CA  . TRP A 1 7   ? -0.683  95.938  14.528 1.00 106.79 ? 15  TRP A CA  1 
ATOM   45    C C   . TRP A 1 7   ? 0.475   95.812  15.532 1.00 108.22 ? 15  TRP A C   1 
ATOM   46    O O   . TRP A 1 7   ? 0.399   95.036  16.495 1.00 102.98 ? 15  TRP A O   1 
ATOM   47    C CB  . TRP A 1 7   ? -0.488  95.057  13.281 1.00 94.96  ? 15  TRP A CB  1 
ATOM   48    C CG  . TRP A 1 7   ? -0.664  93.590  13.583 1.00 103.80 ? 15  TRP A CG  1 
ATOM   49    C CD1 . TRP A 1 7   ? 0.322   92.648  13.682 1.00 114.08 ? 15  TRP A CD1 1 
ATOM   50    C CD2 . TRP A 1 7   ? -1.894  92.918  13.946 1.00 122.63 ? 15  TRP A CD2 1 
ATOM   51    N NE1 . TRP A 1 7   ? -0.213  91.431  14.005 1.00 114.85 ? 15  TRP A NE1 1 
ATOM   52    C CE2 . TRP A 1 7   ? -1.564  91.568  14.182 1.00 120.73 ? 15  TRP A CE2 1 
ATOM   53    C CE3 . TRP A 1 7   ? -3.234  93.315  14.075 1.00 147.68 ? 15  TRP A CE3 1 
ATOM   54    C CZ2 . TRP A 1 7   ? -2.536  90.627  14.517 1.00 149.39 ? 15  TRP A CZ2 1 
ATOM   55    C CZ3 . TRP A 1 7   ? -4.197  92.390  14.430 1.00 103.85 ? 15  TRP A CZ3 1 
ATOM   56    C CH2 . TRP A 1 7   ? -3.844  91.059  14.627 1.00 141.78 ? 15  TRP A CH2 1 
ATOM   57    N N   . SER A 1 8   ? 1.530   96.606  15.333 1.00 99.18  ? 16  SER A N   1 
ATOM   58    C CA  . SER A 1 8   ? 2.651   96.670  16.254 1.00 102.44 ? 16  SER A CA  1 
ATOM   59    C C   . SER A 1 8   ? 2.241   97.153  17.655 1.00 112.65 ? 16  SER A C   1 
ATOM   60    O O   . SER A 1 8   ? 2.742   96.644  18.673 1.00 103.14 ? 16  SER A O   1 
ATOM   61    C CB  . SER A 1 8   ? 3.697   97.560  15.664 1.00 68.27  ? 16  SER A CB  1 
ATOM   62    O OG  . SER A 1 8   ? 4.859   97.351  16.438 1.00 80.17  ? 16  SER A OG  1 
ATOM   63    N N   . SER A 1 9   ? 1.317   98.127  17.694 1.00 102.76 ? 17  SER A N   1 
ATOM   64    C CA  . SER A 1 9   ? 0.829   98.647  18.963 1.00 103.86 ? 17  SER A CA  1 
ATOM   65    C C   . SER A 1 9   ? -0.088  97.630  19.644 1.00 115.51 ? 17  SER A C   1 
ATOM   66    O O   . SER A 1 9   ? -0.144  97.531  20.870 1.00 128.26 ? 17  SER A O   1 
ATOM   67    C CB  . SER A 1 9   ? 0.134   99.976  18.801 1.00 95.08  ? 17  SER A CB  1 
ATOM   68    O OG  . SER A 1 9   ? -1.134  99.826  18.168 1.00 90.27  ? 17  SER A OG  1 
ATOM   69    N N   . HIS A 1 10  ? -0.805  96.852  18.828 1.00 97.16  ? 18  HIS A N   1 
ATOM   70    C CA  . HIS A 1 10  ? -1.566  95.713  19.312 1.00 96.47  ? 18  HIS A CA  1 
ATOM   71    C C   . HIS A 1 10  ? -0.660  94.759  20.096 1.00 97.15  ? 18  HIS A C   1 
ATOM   72    O O   . HIS A 1 10  ? -1.005  94.386  21.221 1.00 93.71  ? 18  HIS A O   1 
ATOM   73    C CB  . HIS A 1 10  ? -2.355  95.057  18.165 1.00 80.47  ? 18  HIS A CB  1 
ATOM   74    C CG  . HIS A 1 10  ? -2.850  93.664  18.459 1.00 94.99  ? 18  HIS A CG  1 
ATOM   75    N ND1 . HIS A 1 10  ? -2.062  92.564  18.210 1.00 95.70  ? 18  HIS A ND1 1 
ATOM   76    C CD2 . HIS A 1 10  ? -3.996  93.159  18.957 1.00 102.62 ? 18  HIS A CD2 1 
ATOM   77    C CE1 . HIS A 1 10  ? -2.692  91.455  18.582 1.00 94.22  ? 18  HIS A CE1 1 
ATOM   78    N NE2 . HIS A 1 10  ? -3.875  91.785  19.027 1.00 89.22  ? 18  HIS A NE2 1 
ATOM   79    N N   . ASP A 1 11  ? 0.468   94.340  19.488 1.00 87.81  ? 19  ASP A N   1 
ATOM   80    C CA  . ASP A 1 11  ? 1.317   93.353  20.130 1.00 78.89  ? 19  ASP A CA  1 
ATOM   81    C C   . ASP A 1 11  ? 1.765   93.987  21.438 1.00 91.16  ? 19  ASP A C   1 
ATOM   82    O O   . ASP A 1 11  ? 1.928   93.280  22.472 1.00 76.03  ? 19  ASP A O   1 
ATOM   83    C CB  . ASP A 1 11  ? 2.478   92.927  19.255 1.00 77.25  ? 19  ASP A CB  1 
ATOM   84    C CG  . ASP A 1 11  ? 2.146   92.344  17.891 1.00 107.74 ? 19  ASP A CG  1 
ATOM   85    O OD1 . ASP A 1 11  ? 0.939   92.100  17.554 1.00 91.70  ? 19  ASP A OD1 1 
ATOM   86    O OD2 . ASP A 1 11  ? 3.109   92.165  17.142 1.00 145.85 ? 19  ASP A OD2 1 
ATOM   87    N N   . ALA A 1 12  ? 1.923   95.335  21.360 1.00 67.41  ? 20  ALA A N   1 
ATOM   88    C CA  . ALA A 1 12  ? 2.467   96.067  22.490 1.00 83.97  ? 20  ALA A CA  1 
ATOM   89    C C   . ALA A 1 12  ? 1.501   95.957  23.672 1.00 111.65 ? 20  ALA A C   1 
ATOM   90    O O   . ALA A 1 12  ? 1.910   95.537  24.760 1.00 118.68 ? 20  ALA A O   1 
ATOM   91    C CB  . ALA A 1 12  ? 2.734   97.484  22.118 1.00 70.13  ? 20  ALA A CB  1 
ATOM   92    N N   . MET A 1 13  ? 0.214   96.185  23.368 1.00 101.61 ? 21  MET A N   1 
ATOM   93    C CA  . MET A 1 13  ? -0.828  96.244  24.372 1.00 103.33 ? 21  MET A CA  1 
ATOM   94    C C   . MET A 1 13  ? -0.750  95.010  25.245 1.00 126.05 ? 21  MET A C   1 
ATOM   95    O O   . MET A 1 13  ? -0.741  95.123  26.474 1.00 143.74 ? 21  MET A O   1 
ATOM   96    C CB  . MET A 1 13  ? -2.204  96.173  23.710 1.00 94.13  ? 21  MET A CB  1 
ATOM   97    C CG  . MET A 1 13  ? -3.289  96.647  24.666 1.00 98.82  ? 21  MET A CG  1 
ATOM   98    S SD  . MET A 1 13  ? -4.975  96.443  24.050 1.00 126.11 ? 21  MET A SD  1 
ATOM   99    C CE  . MET A 1 13  ? -4.916  96.334  22.249 1.00 92.09  ? 21  MET A CE  1 
ATOM   100   N N   . LEU A 1 14  ? -0.725  93.852  24.566 1.00 116.17 ? 22  LEU A N   1 
ATOM   101   C CA  . LEU A 1 14  ? -0.828  92.543  25.203 1.00 89.08  ? 22  LEU A CA  1 
ATOM   102   C C   . LEU A 1 14  ? 0.322   92.326  26.173 1.00 121.16 ? 22  LEU A C   1 
ATOM   103   O O   . LEU A 1 14  ? 0.191   91.510  27.088 1.00 141.43 ? 22  LEU A O   1 
ATOM   104   C CB  . LEU A 1 14  ? -0.923  91.388  24.226 1.00 62.04  ? 22  LEU A CB  1 
ATOM   105   C CG  . LEU A 1 14  ? -2.058  91.518  23.199 1.00 74.44  ? 22  LEU A CG  1 
ATOM   106   C CD1 . LEU A 1 14  ? -2.257  90.254  22.353 1.00 64.26  ? 22  LEU A CD1 1 
ATOM   107   C CD2 . LEU A 1 14  ? -3.411  92.083  23.709 1.00 69.44  ? 22  LEU A CD2 1 
ATOM   108   N N   . ALA A 1 15  ? 1.401   93.104  26.008 1.00 122.56 ? 23  ALA A N   1 
ATOM   109   C CA  . ALA A 1 15  ? 2.580   92.849  26.823 1.00 113.53 ? 23  ALA A CA  1 
ATOM   110   C C   . ALA A 1 15  ? 2.842   93.972  27.828 1.00 118.35 ? 23  ALA A C   1 
ATOM   111   O O   . ALA A 1 15  ? 3.564   93.786  28.801 1.00 158.23 ? 23  ALA A O   1 
ATOM   112   C CB  . ALA A 1 15  ? 3.762   92.572  25.946 1.00 103.89 ? 23  ALA A CB  1 
ATOM   113   N N   . GLN A 1 16  ? 2.220   95.133  27.622 1.00 90.24  ? 24  GLN A N   1 
ATOM   114   C CA  . GLN A 1 16  ? 2.484   96.290  28.470 1.00 76.99  ? 24  GLN A CA  1 
ATOM   115   C C   . GLN A 1 16  ? 1.780   96.114  29.823 1.00 55.70  ? 24  GLN A C   1 
ATOM   116   O O   . GLN A 1 16  ? 0.662   95.609  29.890 1.00 62.64  ? 24  GLN A O   1 
ATOM   117   C CB  . GLN A 1 16  ? 1.987   97.427  27.557 1.00 85.21  ? 24  GLN A CB  1 
ATOM   118   C CG  . GLN A 1 16  ? 2.080   98.838  28.110 1.00 80.43  ? 24  GLN A CG  1 
ATOM   119   C CD  . GLN A 1 16  ? 0.765   99.584  27.997 1.00 83.07  ? 24  GLN A CD  1 
ATOM   120   O OE1 . GLN A 1 16  ? -0.247  99.054  27.512 1.00 81.22  ? 24  GLN A OE1 1 
ATOM   121   N NE2 . GLN A 1 16  ? 0.745   100.790 28.535 1.00 94.64  ? 24  GLN A NE2 1 
ATOM   122   N N   . PRO A 1 17  ? 2.405   96.516  30.949 1.00 60.31  ? 25  PRO A N   1 
ATOM   123   C CA  . PRO A 1 17  ? 1.913   96.190  32.301 1.00 77.11  ? 25  PRO A CA  1 
ATOM   124   C C   . PRO A 1 17  ? 0.591   96.825  32.673 1.00 86.64  ? 25  PRO A C   1 
ATOM   125   O O   . PRO A 1 17  ? 0.196   97.818  32.079 1.00 92.43  ? 25  PRO A O   1 
ATOM   126   C CB  . PRO A 1 17  ? 2.967   96.686  33.307 1.00 75.13  ? 25  PRO A CB  1 
ATOM   127   C CG  . PRO A 1 17  ? 4.191   96.908  32.449 1.00 99.93  ? 25  PRO A CG  1 
ATOM   128   C CD  . PRO A 1 17  ? 3.672   97.263  31.021 1.00 89.09  ? 25  PRO A CD  1 
ATOM   129   N N   . LEU A 1 18  ? 0.059   96.309  33.774 1.00 101.18 ? 26  LEU A N   1 
ATOM   130   C CA  . LEU A 1 18  ? -1.231  96.697  34.301 1.00 111.78 ? 26  LEU A CA  1 
ATOM   131   C C   . LEU A 1 18  ? -1.195  98.165  34.673 1.00 113.53 ? 26  LEU A C   1 
ATOM   132   O O   . LEU A 1 18  ? -2.158  98.889  34.357 1.00 106.82 ? 26  LEU A O   1 
ATOM   133   C CB  . LEU A 1 18  ? -1.621  95.911  35.554 1.00 101.04 ? 26  LEU A CB  1 
ATOM   134   C CG  . LEU A 1 18  ? -3.046  96.187  36.037 1.00 78.04  ? 26  LEU A CG  1 
ATOM   135   C CD1 . LEU A 1 18  ? -4.024  95.853  34.902 1.00 98.84  ? 26  LEU A CD1 1 
ATOM   136   C CD2 . LEU A 1 18  ? -3.360  95.308  37.225 1.00 57.37  ? 26  LEU A CD2 1 
ATOM   137   N N   . LYS A 1 19  ? -0.106  98.540  35.379 1.00 102.28 ? 27  LYS A N   1 
ATOM   138   C CA  . LYS A 1 19  ? -0.025  99.894  35.912 1.00 95.88  ? 27  LYS A CA  1 
ATOM   139   C C   . LYS A 1 19  ? -0.277  100.902 34.776 1.00 89.25  ? 27  LYS A C   1 
ATOM   140   O O   . LYS A 1 19  ? -0.895  101.951 34.978 1.00 91.86  ? 27  LYS A O   1 
ATOM   141   C CB  . LYS A 1 19  ? 1.212   100.234 36.759 1.00 97.11  ? 27  LYS A CB  1 
ATOM   142   C CG  . LYS A 1 19  ? 1.059   101.696 37.306 1.00 86.44  ? 27  LYS A CG  1 
ATOM   143   C CD  . LYS A 1 19  ? 1.744   102.425 38.477 1.00 88.83  ? 27  LYS A CD  1 
ATOM   144   C CE  . LYS A 1 19  ? 3.171   102.931 38.652 1.00 99.86  ? 27  LYS A CE  1 
ATOM   145   N NZ  . LYS A 1 19  ? 3.309   104.392 38.576 1.00 97.92  ? 27  LYS A NZ  1 
ATOM   146   N N   . ASP A 1 20  ? 0.160   100.552 33.556 1.00 89.80  ? 28  ASP A N   1 
ATOM   147   C CA  . ASP A 1 20  ? 0.222   101.480 32.432 1.00 84.24  ? 28  ASP A CA  1 
ATOM   148   C C   . ASP A 1 20  ? -1.004  101.313 31.542 1.00 96.22  ? 28  ASP A C   1 
ATOM   149   O O   . ASP A 1 20  ? -1.521  102.278 31.001 1.00 128.94 ? 28  ASP A O   1 
ATOM   150   C CB  . ASP A 1 20  ? 1.496   101.288 31.628 1.00 82.96  ? 28  ASP A CB  1 
ATOM   151   C CG  . ASP A 1 20  ? 2.790   100.983 32.390 1.00 113.18 ? 28  ASP A CG  1 
ATOM   152   O OD1 . ASP A 1 20  ? 2.808   100.975 33.668 1.00 107.03 ? 28  ASP A OD1 1 
ATOM   153   O OD2 . ASP A 1 20  ? 3.804   100.780 31.702 1.00 99.81  ? 28  ASP A OD2 1 
ATOM   154   N N   . SER A 1 21  ? -1.440  100.065 31.371 1.00 118.47 ? 29  SER A N   1 
ATOM   155   C CA  . SER A 1 21  ? -2.653  99.749  30.638 1.00 103.44 ? 29  SER A CA  1 
ATOM   156   C C   . SER A 1 21  ? -3.751  99.612  31.688 1.00 83.84  ? 29  SER A C   1 
ATOM   157   O O   . SER A 1 21  ? -3.680  98.710  32.524 1.00 92.14  ? 29  SER A O   1 
ATOM   158   C CB  . SER A 1 21  ? -2.418  98.458  29.844 1.00 101.52 ? 29  SER A CB  1 
ATOM   159   O OG  . SER A 1 21  ? -3.627  97.815  29.475 1.00 139.66 ? 29  SER A OG  1 
ATOM   160   N N   . ASP A 1 22  ? -4.731  100.519 31.703 1.00 62.21  ? 30  ASP A N   1 
ATOM   161   C CA  . ASP A 1 22  ? -5.845  100.399 32.635 1.00 94.94  ? 30  ASP A CA  1 
ATOM   162   C C   . ASP A 1 22  ? -5.385  100.711 34.059 1.00 103.76 ? 30  ASP A C   1 
ATOM   163   O O   . ASP A 1 22  ? -5.316  99.847  34.963 1.00 83.98  ? 30  ASP A O   1 
ATOM   164   C CB  . ASP A 1 22  ? -6.546  99.065  32.476 1.00 103.59 ? 30  ASP A CB  1 
ATOM   165   C CG  . ASP A 1 22  ? -7.832  98.869  33.245 1.00 90.87  ? 30  ASP A CG  1 
ATOM   166   O OD1 . ASP A 1 22  ? -8.051  99.597  34.226 1.00 117.71 ? 30  ASP A OD1 1 
ATOM   167   O OD2 . ASP A 1 22  ? -8.629  98.042  32.767 1.00 59.10  ? 30  ASP A OD2 1 
ATOM   168   N N   . VAL A 1 23  ? -5.145  102.012 34.236 1.00 104.10 ? 31  VAL A N   1 
ATOM   169   C CA  . VAL A 1 23  ? -4.775  102.538 35.534 1.00 97.89  ? 31  VAL A CA  1 
ATOM   170   C C   . VAL A 1 23  ? -5.938  102.443 36.520 1.00 90.81  ? 31  VAL A C   1 
ATOM   171   O O   . VAL A 1 23  ? -5.717  102.340 37.721 1.00 103.27 ? 31  VAL A O   1 
ATOM   172   C CB  . VAL A 1 23  ? -4.316  103.993 35.427 1.00 94.69  ? 31  VAL A CB  1 
ATOM   173   C CG1 . VAL A 1 23  ? -3.644  104.395 36.742 1.00 82.77  ? 31  VAL A CG1 1 
ATOM   174   C CG2 . VAL A 1 23  ? -3.501  104.245 34.148 1.00 91.50  ? 31  VAL A CG2 1 
ATOM   175   N N   . GLU A 1 24  ? -7.176  102.464 36.003 1.00 87.21  ? 32  GLU A N   1 
ATOM   176   C CA  . GLU A 1 24  ? -8.372  102.452 36.839 1.00 95.25  ? 32  GLU A CA  1 
ATOM   177   C C   . GLU A 1 24  ? -8.317  101.199 37.708 1.00 98.61  ? 32  GLU A C   1 
ATOM   178   O O   . GLU A 1 24  ? -8.403  101.294 38.944 1.00 105.70 ? 32  GLU A O   1 
ATOM   179   C CB  . GLU A 1 24  ? -9.669  102.590 36.032 1.00 81.87  ? 32  GLU A CB  1 
ATOM   180   C CG  . GLU A 1 24  ? -9.425  103.291 34.689 1.00 70.13  ? 32  GLU A CG  1 
ATOM   181   C CD  . GLU A 1 24  ? -10.477 103.004 33.651 1.00 117.06 ? 32  GLU A CD  1 
ATOM   182   O OE1 . GLU A 1 24  ? -10.225 103.328 32.468 1.00 120.76 ? 32  GLU A OE1 1 
ATOM   183   O OE2 . GLU A 1 24  ? -11.551 102.477 34.043 1.00 151.07 ? 32  GLU A OE2 1 
ATOM   184   N N   . VAL A 1 25  ? -8.158  100.036 37.053 1.00 86.96  ? 33  VAL A N   1 
ATOM   185   C CA  . VAL A 1 25  ? -8.120  98.785  37.790 1.00 94.33  ? 33  VAL A CA  1 
ATOM   186   C C   . VAL A 1 25  ? -6.930  98.776  38.755 1.00 104.36 ? 33  VAL A C   1 
ATOM   187   O O   . VAL A 1 25  ? -7.069  98.387  39.921 1.00 105.82 ? 33  VAL A O   1 
ATOM   188   C CB  . VAL A 1 25  ? -8.045  97.581  36.831 1.00 88.55  ? 33  VAL A CB  1 
ATOM   189   C CG1 . VAL A 1 25  ? -7.777  96.303  37.607 1.00 79.88  ? 33  VAL A CG1 1 
ATOM   190   C CG2 . VAL A 1 25  ? -9.304  97.412  35.991 1.00 75.63  ? 33  VAL A CG2 1 
ATOM   191   N N   . TYR A 1 26  ? -5.771  99.206  38.234 1.00 91.76  ? 34  TYR A N   1 
ATOM   192   C CA  . TYR A 1 26  ? -4.554  99.275  39.020 1.00 100.26 ? 34  TYR A CA  1 
ATOM   193   C C   . TYR A 1 26  ? -4.836  99.954  40.368 1.00 103.05 ? 34  TYR A C   1 
ATOM   194   O O   . TYR A 1 26  ? -4.486  99.426  41.445 1.00 104.85 ? 34  TYR A O   1 
ATOM   195   C CB  . TYR A 1 26  ? -3.386  99.914  38.254 1.00 98.57  ? 34  TYR A CB  1 
ATOM   196   C CG  . TYR A 1 26  ? -2.092  99.863  39.054 1.00 104.18 ? 34  TYR A CG  1 
ATOM   197   C CD1 . TYR A 1 26  ? -1.268  98.751  38.946 1.00 90.80  ? 34  TYR A CD1 1 
ATOM   198   C CD2 . TYR A 1 26  ? -1.726  100.852 39.961 1.00 95.66  ? 34  TYR A CD2 1 
ATOM   199   C CE1 . TYR A 1 26  ? -0.099  98.627  39.672 1.00 87.02  ? 34  TYR A CE1 1 
ATOM   200   C CE2 . TYR A 1 26  ? -0.570  100.730 40.718 1.00 92.80  ? 34  TYR A CE2 1 
ATOM   201   C CZ  . TYR A 1 26  ? 0.246   99.617  40.574 1.00 106.86 ? 34  TYR A CZ  1 
ATOM   202   O OH  . TYR A 1 26  ? 1.392   99.489  41.317 1.00 108.91 ? 34  TYR A OH  1 
ATOM   203   N N   . ASN A 1 27  ? -5.489  101.130 40.302 1.00 78.09  ? 35  ASN A N   1 
ATOM   204   C CA  . ASN A 1 27  ? -5.770  101.869 41.537 1.00 92.11  ? 35  ASN A CA  1 
ATOM   205   C C   . ASN A 1 27  ? -6.662  101.041 42.472 1.00 88.31  ? 35  ASN A C   1 
ATOM   206   O O   . ASN A 1 27  ? -6.390  100.932 43.678 1.00 62.39  ? 35  ASN A O   1 
ATOM   207   C CB  . ASN A 1 27  ? -6.671  103.091 41.422 1.00 83.79  ? 35  ASN A CB  1 
ATOM   208   C CG  . ASN A 1 27  ? -6.239  104.156 40.462 1.00 100.40 ? 35  ASN A CG  1 
ATOM   209   O OD1 . ASN A 1 27  ? -5.057  104.284 40.080 1.00 94.38  ? 35  ASN A OD1 1 
ATOM   210   N ND2 . ASN A 1 27  ? -7.253  104.939 40.118 1.00 99.93  ? 35  ASN A ND2 1 
ATOM   211   N N   . ILE A 1 28  ? -7.724  100.481 41.866 1.00 81.29  ? 36  ILE A N   1 
ATOM   212   C CA  . ILE A 1 28  ? -8.688  99.718  42.621 1.00 74.71  ? 36  ILE A CA  1 
ATOM   213   C C   . ILE A 1 28  ? -7.939  98.650  43.430 1.00 87.83  ? 36  ILE A C   1 
ATOM   214   O O   . ILE A 1 28  ? -8.102  98.542  44.664 1.00 61.86  ? 36  ILE A O   1 
ATOM   215   C CB  . ILE A 1 28  ? -9.749  99.096  41.699 1.00 65.11  ? 36  ILE A CB  1 
ATOM   216   C CG1 . ILE A 1 28  ? -10.539 100.153 40.923 1.00 56.79  ? 36  ILE A CG1 1 
ATOM   217   C CG2 . ILE A 1 28  ? -10.644 98.154  42.527 1.00 68.41  ? 36  ILE A CG2 1 
ATOM   218   C CD1 . ILE A 1 28  ? -11.914 99.694  40.473 1.00 82.04  ? 36  ILE A CD1 1 
ATOM   219   N N   . ILE A 1 29  ? -7.098  97.869  42.732 1.00 79.60  ? 37  ILE A N   1 
ATOM   220   C CA  . ILE A 1 29  ? -6.340  96.836  43.418 1.00 90.39  ? 37  ILE A CA  1 
ATOM   221   C C   . ILE A 1 29  ? -5.538  97.429  44.581 1.00 106.93 ? 37  ILE A C   1 
ATOM   222   O O   . ILE A 1 29  ? -5.547  96.885  45.707 1.00 98.37  ? 37  ILE A O   1 
ATOM   223   C CB  . ILE A 1 29  ? -5.429  96.050  42.466 1.00 90.13  ? 37  ILE A CB  1 
ATOM   224   C CG1 . ILE A 1 29  ? -6.230  95.462  41.320 1.00 103.18 ? 37  ILE A CG1 1 
ATOM   225   C CG2 . ILE A 1 29  ? -4.654  94.971  43.243 1.00 92.04  ? 37  ILE A CG2 1 
ATOM   226   C CD1 . ILE A 1 29  ? -5.388  94.765  40.266 1.00 84.79  ? 37  ILE A CD1 1 
ATOM   227   N N   . LYS A 1 30  ? -4.800  98.517  44.282 1.00 105.60 ? 38  LYS A N   1 
ATOM   228   C CA  . LYS A 1 30  ? -3.978  99.151  45.300 1.00 108.09 ? 38  LYS A CA  1 
ATOM   229   C C   . LYS A 1 30  ? -4.833  99.664  46.458 1.00 107.73 ? 38  LYS A C   1 
ATOM   230   O O   . LYS A 1 30  ? -4.487  99.416  47.611 1.00 112.60 ? 38  LYS A O   1 
ATOM   231   C CB  . LYS A 1 30  ? -2.999  100.157 44.697 1.00 80.90  ? 38  LYS A CB  1 
ATOM   232   C CG  . LYS A 1 30  ? -1.713  99.503  44.194 1.00 90.61  ? 38  LYS A CG  1 
ATOM   233   C CD  . LYS A 1 30  ? -0.805  100.365 43.301 1.00 94.83  ? 38  LYS A CD  1 
ATOM   234   C CE  . LYS A 1 30  ? -0.239  101.728 43.761 1.00 150.04 ? 38  LYS A CE  1 
ATOM   235   N NZ  . LYS A 1 30  ? 0.540   101.847 45.005 1.00 171.40 ? 38  LYS A NZ  1 
ATOM   236   N N   . LYS A 1 31  ? -5.942  100.353 46.157 1.00 79.32  ? 39  LYS A N   1 
ATOM   237   C CA  . LYS A 1 31  ? -6.817  100.840 47.218 1.00 68.83  ? 39  LYS A CA  1 
ATOM   238   C C   . LYS A 1 31  ? -7.295  99.680  48.094 1.00 69.51  ? 39  LYS A C   1 
ATOM   239   O O   . LYS A 1 31  ? -7.383  99.836  49.313 1.00 71.49  ? 39  LYS A O   1 
ATOM   240   C CB  . LYS A 1 31  ? -8.029  101.674 46.782 1.00 73.58  ? 39  LYS A CB  1 
ATOM   241   C CG  . LYS A 1 31  ? -7.754  102.976 46.029 1.00 71.37  ? 39  LYS A CG  1 
ATOM   242   C CD  . LYS A 1 31  ? -9.029  103.587 45.461 1.00 71.15  ? 39  LYS A CD  1 
ATOM   243   C CE  . LYS A 1 31  ? -8.805  104.105 44.054 1.00 91.30  ? 39  LYS A CE  1 
ATOM   244   N NZ  . LYS A 1 31  ? -9.940  104.237 43.119 1.00 107.43 ? 39  LYS A NZ  1 
ATOM   245   N N   . GLU A 1 32  ? -7.610  98.524  47.486 1.00 82.05  ? 40  GLU A N   1 
ATOM   246   C CA  . GLU A 1 32  ? -8.123  97.379  48.244 1.00 110.34 ? 40  GLU A CA  1 
ATOM   247   C C   . GLU A 1 32  ? -7.012  96.815  49.138 1.00 109.71 ? 40  GLU A C   1 
ATOM   248   O O   . GLU A 1 32  ? -7.244  96.428  50.306 1.00 73.87  ? 40  GLU A O   1 
ATOM   249   C CB  . GLU A 1 32  ? -8.613  96.307  47.271 1.00 103.31 ? 40  GLU A CB  1 
ATOM   250   C CG  . GLU A 1 32  ? -8.955  94.973  47.935 1.00 86.46  ? 40  GLU A CG  1 
ATOM   251   C CD  . GLU A 1 32  ? -10.066 95.057  48.973 1.00 114.62 ? 40  GLU A CD  1 
ATOM   252   O OE1 . GLU A 1 32  ? -10.826 96.056  49.145 1.00 123.32 ? 40  GLU A OE1 1 
ATOM   253   O OE2 . GLU A 1 32  ? -10.136 94.035  49.667 1.00 134.96 ? 40  GLU A OE2 1 
ATOM   254   N N   . SER A 1 33  ? -5.796  96.775  48.552 1.00 87.80  ? 41  SER A N   1 
ATOM   255   C CA  . SER A 1 33  ? -4.656  96.316  49.307 1.00 85.82  ? 41  SER A CA  1 
ATOM   256   C C   . SER A 1 33  ? -4.465  97.171  50.561 1.00 110.03 ? 41  SER A C   1 
ATOM   257   O O   . SER A 1 33  ? -4.134  96.662  51.641 1.00 102.01 ? 41  SER A O   1 
ATOM   258   C CB  . SER A 1 33  ? -3.435  96.316  48.476 1.00 68.39  ? 41  SER A CB  1 
ATOM   259   O OG  . SER A 1 33  ? -2.379  95.827  49.307 1.00 87.58  ? 41  SER A OG  1 
ATOM   260   N N   . ASN A 1 34  ? -4.665  98.485  50.388 1.00 88.49  ? 42  ASN A N   1 
ATOM   261   C CA  . ASN A 1 34  ? -4.500  99.417  51.488 1.00 105.02 ? 42  ASN A CA  1 
ATOM   262   C C   . ASN A 1 34  ? -5.591  99.149  52.523 1.00 110.46 ? 42  ASN A C   1 
ATOM   263   O O   . ASN A 1 34  ? -5.308  99.142  53.729 1.00 91.81  ? 42  ASN A O   1 
ATOM   264   C CB  . ASN A 1 34  ? -4.349  100.854 51.002 1.00 98.91  ? 42  ASN A CB  1 
ATOM   265   C CG  . ASN A 1 34  ? -4.777  101.844 52.063 1.00 116.65 ? 42  ASN A CG  1 
ATOM   266   O OD1 . ASN A 1 34  ? -4.131  101.948 53.119 1.00 98.54  ? 42  ASN A OD1 1 
ATOM   267   N ND2 . ASN A 1 34  ? -5.930  102.470 51.842 1.00 105.67 ? 42  ASN A ND2 1 
ATOM   268   N N   . ARG A 1 35  ? -6.821  98.940  52.024 1.00 99.68  ? 43  ARG A N   1 
ATOM   269   C CA  . ARG A 1 35  ? -7.957  98.670  52.893 1.00 112.73 ? 43  ARG A CA  1 
ATOM   270   C C   . ARG A 1 35  ? -7.627  97.468  53.794 1.00 121.35 ? 43  ARG A C   1 
ATOM   271   O O   . ARG A 1 35  ? -7.888  97.523  55.012 1.00 90.85  ? 43  ARG A O   1 
ATOM   272   C CB  . ARG A 1 35  ? -9.289  98.537  52.136 1.00 84.75  ? 43  ARG A CB  1 
ATOM   273   C CG  . ARG A 1 35  ? -10.321 97.850  53.035 1.00 89.07  ? 43  ARG A CG  1 
ATOM   274   C CD  . ARG A 1 35  ? -11.324 97.026  52.224 1.00 80.78  ? 43  ARG A CD  1 
ATOM   275   N NE  . ARG A 1 35  ? -11.821 95.891  53.002 1.00 71.18  ? 43  ARG A NE  1 
ATOM   276   C CZ  . ARG A 1 35  ? -11.401 94.616  52.925 1.00 84.94  ? 43  ARG A CZ  1 
ATOM   277   N NH1 . ARG A 1 35  ? -10.376 94.368  52.185 1.00 121.54 ? 43  ARG A NH1 1 
ATOM   278   N NH2 . ARG A 1 35  ? -11.880 93.587  53.636 1.00 70.94  ? 43  ARG A NH2 1 
ATOM   279   N N   . GLN A 1 36  ? -7.077  96.396  53.166 1.00 100.33 ? 44  GLN A N   1 
ATOM   280   C CA  . GLN A 1 36  ? -6.784  95.144  53.850 1.00 95.06  ? 44  GLN A CA  1 
ATOM   281   C C   . GLN A 1 36  ? -5.730  95.410  54.916 1.00 103.57 ? 44  GLN A C   1 
ATOM   282   O O   . GLN A 1 36  ? -5.754  94.758  55.964 1.00 115.17 ? 44  GLN A O   1 
ATOM   283   C CB  . GLN A 1 36  ? -6.354  93.969  52.958 1.00 86.57  ? 44  GLN A CB  1 
ATOM   284   C CG  . GLN A 1 36  ? -7.437  93.344  52.085 1.00 96.39  ? 44  GLN A CG  1 
ATOM   285   C CD  . GLN A 1 36  ? -6.941  92.527  50.907 1.00 109.87 ? 44  GLN A CD  1 
ATOM   286   O OE1 . GLN A 1 36  ? -5.999  91.725  51.019 1.00 106.87 ? 44  GLN A OE1 1 
ATOM   287   N NE2 . GLN A 1 36  ? -7.563  92.725  49.745 1.00 93.40  ? 44  GLN A NE2 1 
ATOM   288   N N   . ARG A 1 37  ? -4.809  96.344  54.613 1.00 91.37  ? 45  ARG A N   1 
ATOM   289   C CA  . ARG A 1 37  ? -3.648  96.608  55.447 1.00 108.68 ? 45  ARG A CA  1 
ATOM   290   C C   . ARG A 1 37  ? -4.055  97.288  56.753 1.00 116.34 ? 45  ARG A C   1 
ATOM   291   O O   . ARG A 1 37  ? -3.563  96.909  57.827 1.00 87.50  ? 45  ARG A O   1 
ATOM   292   C CB  . ARG A 1 37  ? -2.616  97.443  54.683 1.00 136.87 ? 45  ARG A CB  1 
ATOM   293   C CG  . ARG A 1 37  ? -1.232  97.509  55.313 1.00 147.21 ? 45  ARG A CG  1 
ATOM   294   C CD  . ARG A 1 37  ? -0.310  98.406  54.452 1.00 121.60 ? 45  ARG A CD  1 
ATOM   295   N NE  . ARG A 1 37  ? -0.771  99.797  54.566 1.00 137.59 ? 45  ARG A NE  1 
ATOM   296   C CZ  . ARG A 1 37  ? -0.801  100.547 55.693 1.00 149.32 ? 45  ARG A CZ  1 
ATOM   297   N NH1 . ARG A 1 37  ? -1.419  101.727 55.677 1.00 106.30 ? 45  ARG A NH1 1 
ATOM   298   N NH2 . ARG A 1 37  ? -0.287  100.110 56.844 1.00 126.27 ? 45  ARG A NH2 1 
ATOM   299   N N   . VAL A 1 38  ? -4.931  98.301  56.656 1.00 109.63 ? 46  VAL A N   1 
ATOM   300   C CA  . VAL A 1 38  ? -5.242  99.122  57.816 1.00 102.84 ? 46  VAL A CA  1 
ATOM   301   C C   . VAL A 1 38  ? -6.383  98.564  58.661 1.00 107.71 ? 46  VAL A C   1 
ATOM   302   O O   . VAL A 1 38  ? -6.626  99.090  59.756 1.00 140.55 ? 46  VAL A O   1 
ATOM   303   C CB  . VAL A 1 38  ? -5.614  100.535 57.375 1.00 109.84 ? 46  VAL A CB  1 
ATOM   304   C CG1 . VAL A 1 38  ? -4.497  101.152 56.553 1.00 120.99 ? 46  VAL A CG1 1 
ATOM   305   C CG2 . VAL A 1 38  ? -6.985  100.536 56.685 1.00 98.33  ? 46  VAL A CG2 1 
ATOM   306   N N   . GLY A 1 39  ? -7.105  97.554  58.158 1.00 89.90  ? 47  GLY A N   1 
ATOM   307   C CA  . GLY A 1 39  ? -8.243  97.022  58.888 1.00 82.70  ? 47  GLY A CA  1 
ATOM   308   C C   . GLY A 1 39  ? -7.855  95.839  59.781 1.00 93.38  ? 47  GLY A C   1 
ATOM   309   O O   . GLY A 1 39  ? -6.863  95.132  59.560 1.00 103.86 ? 47  GLY A O   1 
ATOM   310   N N   . LEU A 1 40  ? -8.681  95.617  60.803 1.00 91.65  ? 48  LEU A N   1 
ATOM   311   C CA  . LEU A 1 40  ? -8.614  94.405  61.592 1.00 97.88  ? 48  LEU A CA  1 
ATOM   312   C C   . LEU A 1 40  ? -9.616  93.387  61.046 1.00 105.07 ? 48  LEU A C   1 
ATOM   313   O O   . LEU A 1 40  ? -10.824 93.528  61.275 1.00 111.77 ? 48  LEU A O   1 
ATOM   314   C CB  . LEU A 1 40  ? -8.942  94.778  63.034 1.00 103.53 ? 48  LEU A CB  1 
ATOM   315   C CG  . LEU A 1 40  ? -7.842  95.482  63.827 1.00 98.27  ? 48  LEU A CG  1 
ATOM   316   C CD1 . LEU A 1 40  ? -8.326  95.578  65.248 1.00 96.46  ? 48  LEU A CD1 1 
ATOM   317   C CD2 . LEU A 1 40  ? -6.608  94.605  63.847 1.00 111.92 ? 48  LEU A CD2 1 
ATOM   318   N N   . GLU A 1 41  ? -9.093  92.375  60.333 1.00 90.28  ? 49  GLU A N   1 
ATOM   319   C CA  . GLU A 1 41  ? -9.951  91.373  59.727 1.00 87.36  ? 49  GLU A CA  1 
ATOM   320   C C   . GLU A 1 41  ? -10.267 90.205  60.675 1.00 106.10 ? 49  GLU A C   1 
ATOM   321   O O   . GLU A 1 41  ? -9.438  89.312  60.939 1.00 101.98 ? 49  GLU A O   1 
ATOM   322   C CB  . GLU A 1 41  ? -9.508  90.858  58.375 1.00 64.02  ? 49  GLU A CB  1 
ATOM   323   C CG  . GLU A 1 41  ? -10.757 90.257  57.742 1.00 73.53  ? 49  GLU A CG  1 
ATOM   324   C CD  . GLU A 1 41  ? -11.066 91.370  56.796 1.00 105.90 ? 49  GLU A CD  1 
ATOM   325   O OE1 . GLU A 1 41  ? -10.161 92.212  56.631 1.00 92.87  ? 49  GLU A OE1 1 
ATOM   326   O OE2 . GLU A 1 41  ? -12.152 91.336  56.176 1.00 162.92 ? 49  GLU A OE2 1 
ATOM   327   N N   . LEU A 1 42  ? -11.528 90.170  61.132 1.00 97.41  ? 50  LEU A N   1 
ATOM   328   C CA  . LEU A 1 42  ? -11.998 89.066  61.958 1.00 88.80  ? 50  LEU A CA  1 
ATOM   329   C C   . LEU A 1 42  ? -13.142 88.289  61.294 1.00 126.24 ? 50  LEU A C   1 
ATOM   330   O O   . LEU A 1 42  ? -13.811 87.484  61.952 1.00 127.36 ? 50  LEU A O   1 
ATOM   331   C CB  . LEU A 1 42  ? -12.443 89.578  63.314 1.00 79.88  ? 50  LEU A CB  1 
ATOM   332   C CG  . LEU A 1 42  ? -11.314 89.971  64.261 1.00 77.98  ? 50  LEU A CG  1 
ATOM   333   C CD1 . LEU A 1 42  ? -11.104 91.490  64.131 1.00 73.24  ? 50  LEU A CD1 1 
ATOM   334   C CD2 . LEU A 1 42  ? -11.633 89.485  65.675 1.00 73.78  ? 50  LEU A CD2 1 
ATOM   335   N N   . ILE A 1 43  ? -13.372 88.516  59.994 1.00 112.04 ? 51  ILE A N   1 
ATOM   336   C CA  . ILE A 1 43  ? -14.291 87.648  59.272 1.00 101.67 ? 51  ILE A CA  1 
ATOM   337   C C   . ILE A 1 43  ? -13.734 86.218  59.156 1.00 85.61  ? 51  ILE A C   1 
ATOM   338   O O   . ILE A 1 43  ? -12.730 85.965  58.456 1.00 52.73  ? 51  ILE A O   1 
ATOM   339   C CB  . ILE A 1 43  ? -14.537 88.221  57.877 1.00 106.62 ? 51  ILE A CB  1 
ATOM   340   C CG1 . ILE A 1 43  ? -14.967 89.655  57.894 1.00 96.93  ? 51  ILE A CG1 1 
ATOM   341   C CG2 . ILE A 1 43  ? -15.511 87.311  57.137 1.00 133.32 ? 51  ILE A CG2 1 
ATOM   342   C CD1 . ILE A 1 43  ? -15.004 90.235  56.492 1.00 137.44 ? 51  ILE A CD1 1 
ATOM   343   N N   . ALA A 1 44  ? -14.423 85.267  59.802 1.00 64.57  ? 52  ALA A N   1 
ATOM   344   C CA  . ALA A 1 44  ? -13.891 83.907  59.900 1.00 86.16  ? 52  ALA A CA  1 
ATOM   345   C C   . ALA A 1 44  ? -13.561 83.204  58.548 1.00 108.58 ? 52  ALA A C   1 
ATOM   346   O O   . ALA A 1 44  ? -12.778 82.230  58.519 1.00 83.79  ? 52  ALA A O   1 
ATOM   347   C CB  . ALA A 1 44  ? -14.824 83.081  60.747 1.00 71.18  ? 52  ALA A CB  1 
ATOM   348   N N   . SER A 1 45  ? -14.137 83.659  57.415 1.00 98.92  ? 53  SER A N   1 
ATOM   349   C CA  . SER A 1 45  ? -13.884 82.970  56.149 1.00 98.54  ? 53  SER A CA  1 
ATOM   350   C C   . SER A 1 45  ? -12.746 83.610  55.345 1.00 123.80 ? 53  SER A C   1 
ATOM   351   O O   . SER A 1 45  ? -12.366 83.093  54.276 1.00 138.79 ? 53  SER A O   1 
ATOM   352   C CB  . SER A 1 45  ? -15.138 82.787  55.305 1.00 100.23 ? 53  SER A CB  1 
ATOM   353   O OG  . SER A 1 45  ? -15.724 84.055  55.073 1.00 101.83 ? 53  SER A OG  1 
ATOM   354   N N   . GLU A 1 46  ? -12.184 84.701  55.893 1.00 121.90 ? 54  GLU A N   1 
ATOM   355   C CA  . GLU A 1 46  ? -11.100 85.419  55.227 1.00 106.89 ? 54  GLU A CA  1 
ATOM   356   C C   . GLU A 1 46  ? -9.723  84.904  55.641 1.00 89.02  ? 54  GLU A C   1 
ATOM   357   O O   . GLU A 1 46  ? -9.565  84.323  56.738 1.00 74.64  ? 54  GLU A O   1 
ATOM   358   C CB  . GLU A 1 46  ? -11.193 86.920  55.489 1.00 87.93  ? 54  GLU A CB  1 
ATOM   359   C CG  . GLU A 1 46  ? -12.438 87.585  54.918 1.00 121.30 ? 54  GLU A CG  1 
ATOM   360   C CD  . GLU A 1 46  ? -12.281 87.959  53.450 1.00 145.93 ? 54  GLU A CD  1 
ATOM   361   O OE1 . GLU A 1 46  ? -11.992 87.024  52.658 1.00 178.40 ? 54  GLU A OE1 1 
ATOM   362   O OE2 . GLU A 1 46  ? -12.439 89.155  53.099 1.00 121.67 ? 54  GLU A OE2 1 
ATOM   363   N N   . ASN A 1 47  ? -8.765  85.116  54.722 1.00 78.10  ? 55  ASN A N   1 
ATOM   364   C CA  . ASN A 1 47  ? -7.345  84.932  54.995 1.00 90.62  ? 55  ASN A CA  1 
ATOM   365   C C   . ASN A 1 47  ? -6.572  85.703  53.933 1.00 99.31  ? 55  ASN A C   1 
ATOM   366   O O   . ASN A 1 47  ? -7.183  86.240  53.019 1.00 149.79 ? 55  ASN A O   1 
ATOM   367   C CB  . ASN A 1 47  ? -6.926  83.465  54.953 1.00 85.22  ? 55  ASN A CB  1 
ATOM   368   C CG  . ASN A 1 47  ? -5.920  83.096  56.010 1.00 94.32  ? 55  ASN A CG  1 
ATOM   369   O OD1 . ASN A 1 47  ? -4.931  83.819  56.202 1.00 78.95  ? 55  ASN A OD1 1 
ATOM   370   N ND2 . ASN A 1 47  ? -6.165  81.970  56.674 1.00 119.58 ? 55  ASN A ND2 1 
ATOM   371   N N   . PHE A 1 48  ? -5.242  85.768  54.084 1.00 94.73  ? 56  PHE A N   1 
ATOM   372   C CA  . PHE A 1 48  ? -4.378  86.439  53.119 1.00 94.54  ? 56  PHE A CA  1 
ATOM   373   C C   . PHE A 1 48  ? -3.467  85.382  52.492 1.00 104.27 ? 56  PHE A C   1 
ATOM   374   O O   . PHE A 1 48  ? -2.754  84.654  53.200 1.00 109.40 ? 56  PHE A O   1 
ATOM   375   C CB  . PHE A 1 48  ? -3.584  87.609  53.703 1.00 72.63  ? 56  PHE A CB  1 
ATOM   376   C CG  . PHE A 1 48  ? -4.455  88.584  54.484 1.00 88.10  ? 56  PHE A CG  1 
ATOM   377   C CD1 . PHE A 1 48  ? -5.191  89.549  53.791 1.00 87.21  ? 56  PHE A CD1 1 
ATOM   378   C CD2 . PHE A 1 48  ? -4.547  88.549  55.885 1.00 73.19  ? 56  PHE A CD2 1 
ATOM   379   C CE1 . PHE A 1 48  ? -5.977  90.502  54.454 1.00 92.94  ? 56  PHE A CE1 1 
ATOM   380   C CE2 . PHE A 1 48  ? -5.354  89.467  56.556 1.00 91.21  ? 56  PHE A CE2 1 
ATOM   381   C CZ  . PHE A 1 48  ? -6.075  90.442  55.835 1.00 111.19 ? 56  PHE A CZ  1 
ATOM   382   N N   . ALA A 1 49  ? -3.553  85.277  51.164 1.00 94.35  ? 57  ALA A N   1 
ATOM   383   C CA  . ALA A 1 49  ? -2.779  84.303  50.414 1.00 102.12 ? 57  ALA A CA  1 
ATOM   384   C C   . ALA A 1 49  ? -1.343  84.802  50.319 1.00 92.74  ? 57  ALA A C   1 
ATOM   385   O O   . ALA A 1 49  ? -1.129  86.001  50.112 1.00 62.17  ? 57  ALA A O   1 
ATOM   386   C CB  . ALA A 1 49  ? -3.379  84.126  49.026 1.00 123.08 ? 57  ALA A CB  1 
ATOM   387   N N   . SER A 1 50  ? -0.385  83.859  50.411 1.00 101.40 ? 58  SER A N   1 
ATOM   388   C CA  . SER A 1 50  ? 1.040   84.132  50.223 1.00 112.09 ? 58  SER A CA  1 
ATOM   389   C C   . SER A 1 50  ? 1.367   84.668  48.822 1.00 99.86  ? 58  SER A C   1 
ATOM   390   O O   . SER A 1 50  ? 0.613   84.433  47.875 1.00 96.17  ? 58  SER A O   1 
ATOM   391   C CB  . SER A 1 50  ? 1.826   82.900  50.532 1.00 98.43  ? 58  SER A CB  1 
ATOM   392   O OG  . SER A 1 50  ? 1.510   81.907  49.571 1.00 94.67  ? 58  SER A OG  1 
ATOM   393   N N   . ARG A 1 51  ? 2.484   85.393  48.679 1.00 101.12 ? 59  ARG A N   1 
ATOM   394   C CA  . ARG A 1 51  ? 2.814   85.985  47.376 1.00 99.64  ? 59  ARG A CA  1 
ATOM   395   C C   . ARG A 1 51  ? 2.993   84.835  46.400 1.00 127.91 ? 59  ARG A C   1 
ATOM   396   O O   . ARG A 1 51  ? 2.610   84.955  45.234 1.00 114.35 ? 59  ARG A O   1 
ATOM   397   C CB  . ARG A 1 51  ? 4.225   86.266  46.843 1.00 83.61  ? 59  ARG A CB  1 
ATOM   398   C CG  . ARG A 1 51  ? 5.320   86.917  47.672 1.00 136.11 ? 59  ARG A CG  1 
ATOM   399   C CD  . ARG A 1 51  ? 6.497   87.084  46.763 1.00 111.73 ? 59  ARG A CD  1 
ATOM   400   N NE  . ARG A 1 51  ? 6.263   88.291  45.976 1.00 120.00 ? 59  ARG A NE  1 
ATOM   401   C CZ  . ARG A 1 51  ? 7.152   88.993  45.305 1.00 117.99 ? 59  ARG A CZ  1 
ATOM   402   N NH1 . ARG A 1 51  ? 6.696   89.968  44.530 1.00 120.31 ? 59  ARG A NH1 1 
ATOM   403   N NH2 . ARG A 1 51  ? 8.447   88.682  45.372 1.00 80.75  ? 59  ARG A NH2 1 
ATOM   404   N N   . ALA A 1 52  ? 3.591   83.740  46.900 1.00 137.44 ? 60  ALA A N   1 
ATOM   405   C CA  . ALA A 1 52  ? 3.868   82.605  46.039 1.00 125.67 ? 60  ALA A CA  1 
ATOM   406   C C   . ALA A 1 52  ? 2.577   82.200  45.313 1.00 99.42  ? 60  ALA A C   1 
ATOM   407   O O   . ALA A 1 52  ? 2.567   82.103  44.084 1.00 79.78  ? 60  ALA A O   1 
ATOM   408   C CB  . ALA A 1 52  ? 4.526   81.492  46.843 1.00 112.94 ? 60  ALA A CB  1 
ATOM   409   N N   . VAL A 1 53  ? 1.481   82.044  46.077 1.00 87.69  ? 61  VAL A N   1 
ATOM   410   C CA  . VAL A 1 53  ? 0.198   81.593  45.560 1.00 93.77  ? 61  VAL A CA  1 
ATOM   411   C C   . VAL A 1 53  ? -0.329  82.579  44.530 1.00 100.56 ? 61  VAL A C   1 
ATOM   412   O O   . VAL A 1 53  ? -0.661  82.195  43.409 1.00 113.74 ? 61  VAL A O   1 
ATOM   413   C CB  . VAL A 1 53  ? -0.844  81.421  46.670 1.00 104.63 ? 61  VAL A CB  1 
ATOM   414   C CG1 . VAL A 1 53  ? -2.222  81.199  46.059 1.00 97.06  ? 61  VAL A CG1 1 
ATOM   415   C CG2 . VAL A 1 53  ? -0.459  80.300  47.632 1.00 137.95 ? 61  VAL A CG2 1 
ATOM   416   N N   . LEU A 1 54  ? -0.383  83.854  44.926 1.00 87.73  ? 62  LEU A N   1 
ATOM   417   C CA  . LEU A 1 54  ? -0.854  84.886  44.021 1.00 91.20  ? 62  LEU A CA  1 
ATOM   418   C C   . LEU A 1 54  ? 0.004   84.899  42.751 1.00 105.46 ? 62  LEU A C   1 
ATOM   419   O O   . LEU A 1 54  ? -0.502  85.156  41.664 1.00 95.97  ? 62  LEU A O   1 
ATOM   420   C CB  . LEU A 1 54  ? -0.891  86.229  44.745 1.00 79.98  ? 62  LEU A CB  1 
ATOM   421   C CG  . LEU A 1 54  ? -1.733  86.235  46.029 1.00 90.61  ? 62  LEU A CG  1 
ATOM   422   C CD1 . LEU A 1 54  ? -1.328  87.310  47.014 1.00 108.81 ? 62  LEU A CD1 1 
ATOM   423   C CD2 . LEU A 1 54  ? -3.179  86.423  45.669 1.00 93.91  ? 62  LEU A CD2 1 
ATOM   424   N N   . GLU A 1 55  ? 1.313   84.636  42.890 1.00 90.45  ? 63  GLU A N   1 
ATOM   425   C CA  . GLU A 1 55  ? 2.192   84.637  41.729 1.00 87.84  ? 63  GLU A CA  1 
ATOM   426   C C   . GLU A 1 55  ? 1.752   83.564  40.735 1.00 91.35  ? 63  GLU A C   1 
ATOM   427   O O   . GLU A 1 55  ? 1.731   83.795  39.526 1.00 104.66 ? 63  GLU A O   1 
ATOM   428   C CB  . GLU A 1 55  ? 3.669   84.538  42.105 1.00 67.70  ? 63  GLU A CB  1 
ATOM   429   C CG  . GLU A 1 55  ? 4.258   85.898  42.443 1.00 64.98  ? 63  GLU A CG  1 
ATOM   430   C CD  . GLU A 1 55  ? 5.746   85.910  42.676 1.00 96.66  ? 63  GLU A CD  1 
ATOM   431   O OE1 . GLU A 1 55  ? 6.410   85.031  43.285 1.00 128.79 ? 63  GLU A OE1 1 
ATOM   432   O OE2 . GLU A 1 55  ? 6.241   86.953  42.247 1.00 99.34  ? 63  GLU A OE2 1 
ATOM   433   N N   . ALA A 1 56  ? 1.417   82.386  41.250 1.00 67.77  ? 64  ALA A N   1 
ATOM   434   C CA  . ALA A 1 56  ? 0.966   81.272  40.442 1.00 63.42  ? 64  ALA A CA  1 
ATOM   435   C C   . ALA A 1 56  ? -0.359  81.574  39.736 1.00 69.30  ? 64  ALA A C   1 
ATOM   436   O O   . ALA A 1 56  ? -0.495  81.185  38.582 1.00 88.48  ? 64  ALA A O   1 
ATOM   437   C CB  . ALA A 1 56  ? 0.867   80.080  41.350 1.00 63.28  ? 64  ALA A CB  1 
ATOM   438   N N   . LEU A 1 57  ? -1.325  82.227  40.422 1.00 70.51  ? 65  LEU A N   1 
ATOM   439   C CA  . LEU A 1 57  ? -2.600  82.676  39.859 1.00 77.69  ? 65  LEU A CA  1 
ATOM   440   C C   . LEU A 1 57  ? -2.396  83.567  38.627 1.00 92.28  ? 65  LEU A C   1 
ATOM   441   O O   . LEU A 1 57  ? -3.226  83.546  37.725 1.00 102.60 ? 65  LEU A O   1 
ATOM   442   C CB  . LEU A 1 57  ? -3.369  83.515  40.873 1.00 83.35  ? 65  LEU A CB  1 
ATOM   443   C CG  . LEU A 1 57  ? -4.474  82.847  41.685 1.00 101.92 ? 65  LEU A CG  1 
ATOM   444   C CD1 . LEU A 1 57  ? -5.406  83.949  42.143 1.00 99.09  ? 65  LEU A CD1 1 
ATOM   445   C CD2 . LEU A 1 57  ? -5.239  81.838  40.889 1.00 92.66  ? 65  LEU A CD2 1 
ATOM   446   N N   . GLY A 1 58  ? -1.352  84.413  38.648 1.00 90.02  ? 66  GLY A N   1 
ATOM   447   C CA  . GLY A 1 58  ? -1.020  85.377  37.613 1.00 79.79  ? 66  GLY A CA  1 
ATOM   448   C C   . GLY A 1 58  ? -0.519  84.734  36.320 1.00 76.98  ? 66  GLY A C   1 
ATOM   449   O O   . GLY A 1 58  ? -0.645  85.367  35.254 1.00 59.79  ? 66  GLY A O   1 
ATOM   450   N N   . SER A 1 59  ? -0.106  83.448  36.406 1.00 69.89  ? 67  SER A N   1 
ATOM   451   C CA  . SER A 1 59  ? 0.633   82.773  35.342 1.00 105.48 ? 67  SER A CA  1 
ATOM   452   C C   . SER A 1 59  ? -0.185  82.484  34.082 1.00 108.98 ? 67  SER A C   1 
ATOM   453   O O   . SER A 1 59  ? -1.428  82.536  34.078 1.00 92.39  ? 67  SER A O   1 
ATOM   454   C CB  . SER A 1 59  ? 1.283   81.519  35.843 1.00 135.05 ? 67  SER A CB  1 
ATOM   455   O OG  . SER A 1 59  ? 0.300   80.529  36.136 1.00 139.53 ? 67  SER A OG  1 
ATOM   456   N N   . CYS A 1 60  ? 0.579   82.159  33.022 1.00 113.28 ? 68  CYS A N   1 
ATOM   457   C CA  . CYS A 1 60  ? 0.080   81.822  31.688 1.00 110.80 ? 68  CYS A CA  1 
ATOM   458   C C   . CYS A 1 60  ? -0.643  80.476  31.705 1.00 103.26 ? 68  CYS A C   1 
ATOM   459   O O   . CYS A 1 60  ? -1.140  80.053  30.673 1.00 124.43 ? 68  CYS A O   1 
ATOM   460   C CB  . CYS A 1 60  ? 1.211   81.634  30.683 1.00 78.05  ? 68  CYS A CB  1 
ATOM   461   S SG  . CYS A 1 60  ? 2.470   80.525  31.360 1.00 88.27  ? 68  CYS A SG  1 
ATOM   462   N N   . LEU A 1 61  ? -0.698  79.791  32.858 1.00 94.21  ? 69  LEU A N   1 
ATOM   463   C CA  . LEU A 1 61  ? -1.432  78.536  32.987 1.00 101.73 ? 69  LEU A CA  1 
ATOM   464   C C   . LEU A 1 61  ? -2.906  78.794  32.653 1.00 114.08 ? 69  LEU A C   1 
ATOM   465   O O   . LEU A 1 61  ? -3.682  77.871  32.365 1.00 121.83 ? 69  LEU A O   1 
ATOM   466   C CB  . LEU A 1 61  ? -1.248  77.953  34.388 1.00 106.74 ? 69  LEU A CB  1 
ATOM   467   C CG  . LEU A 1 61  ? 0.163   77.473  34.735 1.00 103.28 ? 69  LEU A CG  1 
ATOM   468   C CD1 . LEU A 1 61  ? 0.256   77.077  36.203 1.00 88.87  ? 69  LEU A CD1 1 
ATOM   469   C CD2 . LEU A 1 61  ? 0.415   76.295  33.809 1.00 116.74 ? 69  LEU A CD2 1 
ATOM   470   N N   . ASN A 1 62  ? -3.278  80.080  32.708 1.00 107.53 ? 70  ASN A N   1 
ATOM   471   C CA  . ASN A 1 62  ? -4.629  80.507  32.411 1.00 129.05 ? 70  ASN A CA  1 
ATOM   472   C C   . ASN A 1 62  ? -5.010  80.048  30.998 1.00 137.83 ? 70  ASN A C   1 
ATOM   473   O O   . ASN A 1 62  ? -6.182  79.757  30.738 1.00 185.50 ? 70  ASN A O   1 
ATOM   474   C CB  . ASN A 1 62  ? -4.820  82.007  32.617 1.00 117.20 ? 70  ASN A CB  1 
ATOM   475   C CG  . ASN A 1 62  ? -6.261  82.354  32.304 1.00 132.41 ? 70  ASN A CG  1 
ATOM   476   O OD1 . ASN A 1 62  ? -6.569  82.867  31.213 1.00 135.34 ? 70  ASN A OD1 1 
ATOM   477   N ND2 . ASN A 1 62  ? -7.174  81.923  33.162 1.00 84.86  ? 70  ASN A ND2 1 
ATOM   478   N N   . ASN A 1 63  ? -4.006  79.962  30.116 1.00 117.92 ? 71  ASN A N   1 
ATOM   479   C CA  . ASN A 1 63  ? -4.182  79.902  28.675 1.00 124.91 ? 71  ASN A CA  1 
ATOM   480   C C   . ASN A 1 63  ? -4.575  78.517  28.173 1.00 118.57 ? 71  ASN A C   1 
ATOM   481   O O   . ASN A 1 63  ? -5.324  78.426  27.188 1.00 170.91 ? 71  ASN A O   1 
ATOM   482   C CB  . ASN A 1 63  ? -2.928  80.371  27.948 1.00 103.04 ? 71  ASN A CB  1 
ATOM   483   C CG  . ASN A 1 63  ? -2.712  81.849  28.142 1.00 116.98 ? 71  ASN A CG  1 
ATOM   484   O OD1 . ASN A 1 63  ? -3.667  82.620  28.335 1.00 131.75 ? 71  ASN A OD1 1 
ATOM   485   N ND2 . ASN A 1 63  ? -1.448  82.225  28.096 1.00 103.43 ? 71  ASN A ND2 1 
ATOM   486   N N   . LYS A 1 64  ? -4.084  77.478  28.862 1.00 85.17  ? 72  LYS A N   1 
ATOM   487   C CA  . LYS A 1 64  ? -4.228  76.092  28.413 1.00 92.33  ? 72  LYS A CA  1 
ATOM   488   C C   . LYS A 1 64  ? -5.606  75.480  28.740 1.00 89.85  ? 72  LYS A C   1 
ATOM   489   O O   . LYS A 1 64  ? -6.085  75.479  29.902 1.00 103.98 ? 72  LYS A O   1 
ATOM   490   C CB  . LYS A 1 64  ? -3.062  75.240  28.946 1.00 92.54  ? 72  LYS A CB  1 
ATOM   491   C CG  . LYS A 1 64  ? -3.038  73.797  28.458 1.00 109.12 ? 72  LYS A CG  1 
ATOM   492   C CD  . LYS A 1 64  ? -2.676  73.647  26.987 1.00 134.21 ? 72  LYS A CD  1 
ATOM   493   C CE  . LYS A 1 64  ? -2.812  72.260  26.388 1.00 114.64 ? 72  LYS A CE  1 
ATOM   494   N NZ  . LYS A 1 64  ? -4.015  72.131  25.558 1.00 126.30 ? 72  LYS A NZ  1 
ATOM   495   N N   . TYR A 1 65  ? -6.203  74.902  27.675 1.00 68.63  ? 73  TYR A N   1 
ATOM   496   C CA  . TYR A 1 65  ? -7.398  74.081  27.808 1.00 84.37  ? 73  TYR A CA  1 
ATOM   497   C C   . TYR A 1 65  ? -6.944  72.681  28.182 1.00 89.77  ? 73  TYR A C   1 
ATOM   498   O O   . TYR A 1 65  ? -6.222  72.103  27.381 1.00 145.93 ? 73  TYR A O   1 
ATOM   499   C CB  . TYR A 1 65  ? -8.273  74.075  26.533 1.00 75.85  ? 73  TYR A CB  1 
ATOM   500   C CG  . TYR A 1 65  ? -9.604  74.766  26.829 1.00 81.51  ? 73  TYR A CG  1 
ATOM   501   C CD1 . TYR A 1 65  ? -10.630 74.108  27.514 1.00 93.95  ? 73  TYR A CD1 1 
ATOM   502   C CD2 . TYR A 1 65  ? -9.779  76.124  26.588 1.00 70.22  ? 73  TYR A CD2 1 
ATOM   503   C CE1 . TYR A 1 65  ? -11.790 74.765  27.909 1.00 84.21  ? 73  TYR A CE1 1 
ATOM   504   C CE2 . TYR A 1 65  ? -10.922 76.797  27.004 1.00 71.21  ? 73  TYR A CE2 1 
ATOM   505   C CZ  . TYR A 1 65  ? -11.947 76.119  27.646 1.00 76.54  ? 73  TYR A CZ  1 
ATOM   506   O OH  . TYR A 1 65  ? -13.093 76.774  28.016 1.00 70.43  ? 73  TYR A OH  1 
ATOM   507   N N   . SER A 1 66  ? -7.396  72.133  29.318 1.00 71.68  ? 74  SER A N   1 
ATOM   508   C CA  . SER A 1 66  ? -6.991  70.767  29.629 1.00 75.50  ? 74  SER A CA  1 
ATOM   509   C C   . SER A 1 66  ? -8.182  69.899  30.041 1.00 98.04  ? 74  SER A C   1 
ATOM   510   O O   . SER A 1 66  ? -8.158  69.252  31.097 1.00 120.40 ? 74  SER A O   1 
ATOM   511   C CB  . SER A 1 66  ? -5.887  70.692  30.663 1.00 74.77  ? 74  SER A CB  1 
ATOM   512   O OG  . SER A 1 66  ? -6.270  71.341  31.878 1.00 96.35  ? 74  SER A OG  1 
ATOM   513   N N   . GLU A 1 67  ? -9.210  69.864  29.184 1.00 84.00  ? 75  GLU A N   1 
ATOM   514   C CA  . GLU A 1 67  ? -10.459 69.245  29.588 1.00 97.91  ? 75  GLU A CA  1 
ATOM   515   C C   . GLU A 1 67  ? -10.244 67.769  29.927 1.00 81.87  ? 75  GLU A C   1 
ATOM   516   O O   . GLU A 1 67  ? -9.581  67.037  29.192 1.00 57.64  ? 75  GLU A O   1 
ATOM   517   C CB  . GLU A 1 67  ? -11.559 69.526  28.568 1.00 99.84  ? 75  GLU A CB  1 
ATOM   518   C CG  . GLU A 1 67  ? -12.291 70.812  28.936 1.00 87.77  ? 75  GLU A CG  1 
ATOM   519   C CD  . GLU A 1 67  ? -13.416 71.214  28.051 1.00 93.68  ? 75  GLU A CD  1 
ATOM   520   O OE1 . GLU A 1 67  ? -13.451 70.674  26.944 1.00 112.46 ? 75  GLU A OE1 1 
ATOM   521   O OE2 . GLU A 1 67  ? -14.303 71.913  28.604 1.00 92.13  ? 75  GLU A OE2 1 
ATOM   522   N N   . GLY A 1 68  ? -10.814 67.333  31.047 1.00 63.91  ? 76  GLY A N   1 
ATOM   523   C CA  . GLY A 1 68  ? -10.612 65.929  31.299 1.00 72.53  ? 76  GLY A CA  1 
ATOM   524   C C   . GLY A 1 68  ? -9.664  65.775  32.463 1.00 87.93  ? 76  GLY A C   1 
ATOM   525   O O   . GLY A 1 68  ? -9.486  66.706  33.252 1.00 121.69 ? 76  GLY A O   1 
ATOM   526   N N   . TYR A 1 69  ? -8.994  64.616  32.497 1.00 72.47  ? 77  TYR A N   1 
ATOM   527   C CA  . TYR A 1 69  ? -8.042  64.372  33.564 1.00 77.57  ? 77  TYR A CA  1 
ATOM   528   C C   . TYR A 1 69  ? -6.708  63.873  33.005 1.00 82.43  ? 77  TYR A C   1 
ATOM   529   O O   . TYR A 1 69  ? -6.629  63.487  31.845 1.00 79.28  ? 77  TYR A O   1 
ATOM   530   C CB  . TYR A 1 69  ? -8.783  63.393  34.452 1.00 53.72  ? 77  TYR A CB  1 
ATOM   531   C CG  . TYR A 1 69  ? -10.002 63.989  35.137 1.00 53.84  ? 77  TYR A CG  1 
ATOM   532   C CD1 . TYR A 1 69  ? -9.898  64.676  36.341 1.00 72.08  ? 77  TYR A CD1 1 
ATOM   533   C CD2 . TYR A 1 69  ? -11.274 63.762  34.638 1.00 62.57  ? 77  TYR A CD2 1 
ATOM   534   C CE1 . TYR A 1 69  ? -11.021 65.140  37.017 1.00 76.46  ? 77  TYR A CE1 1 
ATOM   535   C CE2 . TYR A 1 69  ? -12.410 64.177  35.315 1.00 72.72  ? 77  TYR A CE2 1 
ATOM   536   C CZ  . TYR A 1 69  ? -12.283 64.900  36.489 1.00 81.10  ? 77  TYR A CZ  1 
ATOM   537   O OH  . TYR A 1 69  ? -13.443 65.345  37.066 1.00 65.60  ? 77  TYR A OH  1 
ATOM   538   N N   . PRO A 1 70  ? -5.622  63.891  33.809 1.00 59.79  ? 78  PRO A N   1 
ATOM   539   C CA  . PRO A 1 70  ? -4.316  63.470  33.292 1.00 57.47  ? 78  PRO A CA  1 
ATOM   540   C C   . PRO A 1 70  ? -4.393  62.058  32.720 1.00 75.08  ? 78  PRO A C   1 
ATOM   541   O O   . PRO A 1 70  ? -4.874  61.159  33.408 1.00 57.47  ? 78  PRO A O   1 
ATOM   542   C CB  . PRO A 1 70  ? -3.471  63.544  34.537 1.00 62.40  ? 78  PRO A CB  1 
ATOM   543   C CG  . PRO A 1 70  ? -4.173  64.586  35.361 1.00 64.31  ? 78  PRO A CG  1 
ATOM   544   C CD  . PRO A 1 70  ? -5.640  64.266  35.235 1.00 47.73  ? 78  PRO A CD  1 
ATOM   545   N N   . GLY A 1 71  ? -3.981  61.870  31.447 1.00 84.03  ? 79  GLY A N   1 
ATOM   546   C CA  . GLY A 1 71  ? -4.034  60.555  30.808 1.00 74.19  ? 79  GLY A CA  1 
ATOM   547   C C   . GLY A 1 71  ? -5.477  60.084  30.549 1.00 95.41  ? 79  GLY A C   1 
ATOM   548   O O   . GLY A 1 71  ? -5.788  58.895  30.493 1.00 116.90 ? 79  GLY A O   1 
ATOM   549   N N   . GLN A 1 72  ? -6.380  61.062  30.503 1.00 98.69  ? 80  GLN A N   1 
ATOM   550   C CA  . GLN A 1 72  ? -7.694  60.967  29.894 1.00 86.07  ? 80  GLN A CA  1 
ATOM   551   C C   . GLN A 1 72  ? -8.040  62.380  29.437 1.00 85.78  ? 80  GLN A C   1 
ATOM   552   O O   . GLN A 1 72  ? -9.087  62.907  29.836 1.00 125.43 ? 80  GLN A O   1 
ATOM   553   C CB  . GLN A 1 72  ? -8.809  60.585  30.867 1.00 89.41  ? 80  GLN A CB  1 
ATOM   554   C CG  . GLN A 1 72  ? -8.602  59.244  31.540 1.00 101.92 ? 80  GLN A CG  1 
ATOM   555   C CD  . GLN A 1 72  ? -9.753  58.957  32.469 1.00 140.74 ? 80  GLN A CD  1 
ATOM   556   O OE1 . GLN A 1 72  ? -10.538 58.034  32.231 1.00 190.13 ? 80  GLN A OE1 1 
ATOM   557   N NE2 . GLN A 1 72  ? -9.897  59.771  33.508 1.00 154.76 ? 80  GLN A NE2 1 
ATOM   558   N N   . ARG A 1 73  ? -7.169  63.007  28.615 1.00 66.92  ? 81  ARG A N   1 
ATOM   559   C CA  . ARG A 1 73  ? -7.410  64.377  28.172 1.00 71.06  ? 81  ARG A CA  1 
ATOM   560   C C   . ARG A 1 73  ? -8.445  64.395  27.040 1.00 64.02  ? 81  ARG A C   1 
ATOM   561   O O   . ARG A 1 73  ? -8.981  63.352  26.639 1.00 57.22  ? 81  ARG A O   1 
ATOM   562   C CB  . ARG A 1 73  ? -6.103  65.173  28.023 1.00 74.63  ? 81  ARG A CB  1 
ATOM   563   C CG  . ARG A 1 73  ? -5.376  65.480  29.327 1.00 91.79  ? 81  ARG A CG  1 
ATOM   564   C CD  . ARG A 1 73  ? -6.140  66.293  30.395 1.00 82.73  ? 81  ARG A CD  1 
ATOM   565   N NE  . ARG A 1 73  ? -5.275  66.724  31.498 1.00 76.06  ? 81  ARG A NE  1 
ATOM   566   C CZ  . ARG A 1 73  ? -5.599  67.379  32.641 1.00 98.59  ? 81  ARG A CZ  1 
ATOM   567   N NH1 . ARG A 1 73  ? -6.829  67.756  32.933 1.00 82.29  ? 81  ARG A NH1 1 
ATOM   568   N NH2 . ARG A 1 73  ? -4.675  67.689  33.530 1.00 100.66 ? 81  ARG A NH2 1 
ATOM   569   N N   . TYR A 1 74  ? -8.887  65.595  26.702 1.00 61.66  ? 82  TYR A N   1 
ATOM   570   C CA  . TYR A 1 74  ? -9.652  65.815  25.486 1.00 60.86  ? 82  TYR A CA  1 
ATOM   571   C C   . TYR A 1 74  ? -8.816  66.789  24.666 1.00 78.24  ? 82  TYR A C   1 
ATOM   572   O O   . TYR A 1 74  ? -9.261  67.253  23.607 1.00 57.42  ? 82  TYR A O   1 
ATOM   573   C CB  . TYR A 1 74  ? -11.018 66.501  25.722 1.00 68.63  ? 82  TYR A CB  1 
ATOM   574   C CG  . TYR A 1 74  ? -12.282 65.779  26.167 1.00 69.90  ? 82  TYR A CG  1 
ATOM   575   C CD1 . TYR A 1 74  ? -12.276 64.709  27.072 1.00 110.23 ? 82  TYR A CD1 1 
ATOM   576   C CD2 . TYR A 1 74  ? -13.520 66.244  25.695 1.00 59.89  ? 82  TYR A CD2 1 
ATOM   577   C CE1 . TYR A 1 74  ? -13.467 64.076  27.431 1.00 105.30 ? 82  TYR A CE1 1 
ATOM   578   C CE2 . TYR A 1 74  ? -14.708 65.611  26.033 1.00 75.21  ? 82  TYR A CE2 1 
ATOM   579   C CZ  . TYR A 1 74  ? -14.681 64.526  26.905 1.00 103.27 ? 82  TYR A CZ  1 
ATOM   580   O OH  . TYR A 1 74  ? -15.898 63.960  27.195 1.00 80.83  ? 82  TYR A OH  1 
ATOM   581   N N   . TYR A 1 75  ? -7.704  67.299  25.229 1.00 91.27  ? 83  TYR A N   1 
ATOM   582   C CA  . TYR A 1 75  ? -6.823  68.139  24.425 1.00 110.69 ? 83  TYR A CA  1 
ATOM   583   C C   . TYR A 1 75  ? -5.434  67.512  24.344 1.00 114.53 ? 83  TYR A C   1 
ATOM   584   O O   . TYR A 1 75  ? -5.016  66.902  25.310 1.00 127.53 ? 83  TYR A O   1 
ATOM   585   C CB  . TYR A 1 75  ? -6.895  69.612  24.853 1.00 99.71  ? 83  TYR A CB  1 
ATOM   586   C CG  . TYR A 1 75  ? -8.248  70.287  24.642 1.00 109.24 ? 83  TYR A CG  1 
ATOM   587   C CD1 . TYR A 1 75  ? -8.768  70.511  23.356 1.00 110.35 ? 83  TYR A CD1 1 
ATOM   588   C CD2 . TYR A 1 75  ? -9.019  70.695  25.732 1.00 124.30 ? 83  TYR A CD2 1 
ATOM   589   C CE1 . TYR A 1 75  ? -10.015 71.087  23.171 1.00 131.67 ? 83  TYR A CE1 1 
ATOM   590   C CE2 . TYR A 1 75  ? -10.258 71.297  25.555 1.00 152.08 ? 83  TYR A CE2 1 
ATOM   591   C CZ  . TYR A 1 75  ? -10.752 71.508  24.274 1.00 165.05 ? 83  TYR A CZ  1 
ATOM   592   O OH  . TYR A 1 75  ? -11.964 72.140  24.118 1.00 169.12 ? 83  TYR A OH  1 
ATOM   593   N N   . GLY A 1 76  ? -4.735  67.642  23.196 1.00 91.53  ? 84  GLY A N   1 
ATOM   594   C CA  . GLY A 1 76  ? -3.301  67.360  23.133 1.00 106.63 ? 84  GLY A CA  1 
ATOM   595   C C   . GLY A 1 76  ? -2.447  68.409  23.870 1.00 153.94 ? 84  GLY A C   1 
ATOM   596   O O   . GLY A 1 76  ? -2.901  69.532  24.091 1.00 186.58 ? 84  GLY A O   1 
ATOM   597   N N   . GLY A 1 77  ? -1.222  68.028  24.265 1.00 148.85 ? 85  GLY A N   1 
ATOM   598   C CA  . GLY A 1 77  ? -0.195  68.980  24.673 1.00 117.50 ? 85  GLY A CA  1 
ATOM   599   C C   . GLY A 1 77  ? -0.389  69.442  26.111 1.00 95.93  ? 85  GLY A C   1 
ATOM   600   O O   . GLY A 1 77  ? -0.003  70.534  26.524 1.00 105.81 ? 85  GLY A O   1 
ATOM   601   N N   . THR A 1 78  ? -1.008  68.560  26.879 1.00 86.90  ? 86  THR A N   1 
ATOM   602   C CA  . THR A 1 78  ? -1.222  68.788  28.295 1.00 100.02 ? 86  THR A CA  1 
ATOM   603   C C   . THR A 1 78  ? -0.092  68.218  29.157 1.00 89.64  ? 86  THR A C   1 
ATOM   604   O O   . THR A 1 78  ? -0.279  67.997  30.351 1.00 103.10 ? 86  THR A O   1 
ATOM   605   C CB  . THR A 1 78  ? -2.574  68.177  28.672 1.00 107.45 ? 86  THR A CB  1 
ATOM   606   O OG1 . THR A 1 78  ? -2.523  66.787  28.378 1.00 79.27  ? 86  THR A OG1 1 
ATOM   607   C CG2 . THR A 1 78  ? -3.699  68.800  27.866 1.00 115.84 ? 86  THR A CG2 1 
ATOM   608   N N   . GLU A 1 79  ? 1.070   67.947  28.560 1.00 91.12  ? 87  GLU A N   1 
ATOM   609   C CA  . GLU A 1 79  ? 2.137   67.253  29.260 1.00 100.81 ? 87  GLU A CA  1 
ATOM   610   C C   . GLU A 1 79  ? 2.486   67.971  30.569 1.00 106.75 ? 87  GLU A C   1 
ATOM   611   O O   . GLU A 1 79  ? 2.647   67.300  31.590 1.00 101.06 ? 87  GLU A O   1 
ATOM   612   C CB  . GLU A 1 79  ? 3.335   67.023  28.330 1.00 99.57  ? 87  GLU A CB  1 
ATOM   613   C CG  . GLU A 1 79  ? 4.598   66.635  29.099 1.00 110.84 ? 87  GLU A CG  1 
ATOM   614   C CD  . GLU A 1 79  ? 5.889   67.126  28.471 1.00 116.10 ? 87  GLU A CD  1 
ATOM   615   O OE1 . GLU A 1 79  ? 5.783   68.067  27.668 1.00 97.04  ? 87  GLU A OE1 1 
ATOM   616   O OE2 . GLU A 1 79  ? 6.984   66.652  28.805 1.00 122.50 ? 87  GLU A OE2 1 
ATOM   617   N N   . PHE A 1 80  ? 2.611   69.315  30.547 1.00 104.38 ? 88  PHE A N   1 
ATOM   618   C CA  . PHE A 1 80  ? 2.993   70.029  31.758 1.00 99.50  ? 88  PHE A CA  1 
ATOM   619   C C   . PHE A 1 80  ? 1.787   70.215  32.672 1.00 108.07 ? 88  PHE A C   1 
ATOM   620   O O   . PHE A 1 80  ? 1.951   70.195  33.892 1.00 107.15 ? 88  PHE A O   1 
ATOM   621   C CB  . PHE A 1 80  ? 3.779   71.330  31.602 1.00 93.67  ? 88  PHE A CB  1 
ATOM   622   C CG  . PHE A 1 80  ? 5.004   71.086  30.749 1.00 104.71 ? 88  PHE A CG  1 
ATOM   623   C CD1 . PHE A 1 80  ? 6.006   70.228  31.192 1.00 89.89  ? 88  PHE A CD1 1 
ATOM   624   C CD2 . PHE A 1 80  ? 5.115   71.675  29.488 1.00 109.22 ? 88  PHE A CD2 1 
ATOM   625   C CE1 . PHE A 1 80  ? 7.119   70.001  30.395 1.00 91.09  ? 88  PHE A CE1 1 
ATOM   626   C CE2 . PHE A 1 80  ? 6.213   71.410  28.674 1.00 91.41  ? 88  PHE A CE2 1 
ATOM   627   C CZ  . PHE A 1 80  ? 7.216   70.583  29.141 1.00 84.86  ? 88  PHE A CZ  1 
ATOM   628   N N   . ILE A 1 81  ? 0.602   70.409  32.077 1.00 100.59 ? 89  ILE A N   1 
ATOM   629   C CA  . ILE A 1 81  ? -0.619  70.504  32.869 1.00 96.19  ? 89  ILE A CA  1 
ATOM   630   C C   . ILE A 1 81  ? -0.791  69.212  33.668 1.00 103.27 ? 89  ILE A C   1 
ATOM   631   O O   . ILE A 1 81  ? -1.244  69.214  34.818 1.00 101.11 ? 89  ILE A O   1 
ATOM   632   C CB  . ILE A 1 81  ? -1.834  70.786  31.973 1.00 65.98  ? 89  ILE A CB  1 
ATOM   633   C CG1 . ILE A 1 81  ? -1.655  72.139  31.234 1.00 77.45  ? 89  ILE A CG1 1 
ATOM   634   C CG2 . ILE A 1 81  ? -3.151  70.703  32.771 1.00 84.06  ? 89  ILE A CG2 1 
ATOM   635   C CD1 . ILE A 1 81  ? -1.228  73.362  32.065 1.00 85.06  ? 89  ILE A CD1 1 
ATOM   636   N N   . ASP A 1 82  ? -0.424  68.108  33.029 1.00 83.80  ? 90  ASP A N   1 
ATOM   637   C CA  . ASP A 1 82  ? -0.606  66.814  33.645 1.00 91.01  ? 90  ASP A CA  1 
ATOM   638   C C   . ASP A 1 82  ? 0.321   66.686  34.842 1.00 114.51 ? 90  ASP A C   1 
ATOM   639   O O   . ASP A 1 82  ? -0.093  66.177  35.887 1.00 124.17 ? 90  ASP A O   1 
ATOM   640   C CB  . ASP A 1 82  ? -0.427  65.706  32.634 1.00 82.49  ? 90  ASP A CB  1 
ATOM   641   C CG  . ASP A 1 82  ? -1.514  65.682  31.586 1.00 81.69  ? 90  ASP A CG  1 
ATOM   642   O OD1 . ASP A 1 82  ? -2.621  66.152  31.924 1.00 87.71  ? 90  ASP A OD1 1 
ATOM   643   O OD2 . ASP A 1 82  ? -1.171  65.331  30.435 1.00 77.56  ? 90  ASP A OD2 1 
ATOM   644   N N   . GLU A 1 83  ? 1.556   67.190  34.685 1.00 111.19 ? 91  GLU A N   1 
ATOM   645   C CA  . GLU A 1 83  ? 2.494   67.189  35.800 1.00 113.93 ? 91  GLU A CA  1 
ATOM   646   C C   . GLU A 1 83  ? 1.837   67.929  36.952 1.00 103.15 ? 91  GLU A C   1 
ATOM   647   O O   . GLU A 1 83  ? 1.795   67.429  38.069 1.00 87.51  ? 91  GLU A O   1 
ATOM   648   C CB  . GLU A 1 83  ? 3.844   67.839  35.501 1.00 100.68 ? 91  GLU A CB  1 
ATOM   649   C CG  . GLU A 1 83  ? 4.547   67.101  34.366 1.00 132.40 ? 91  GLU A CG  1 
ATOM   650   C CD  . GLU A 1 83  ? 6.042   67.120  34.143 1.00 150.39 ? 91  GLU A CD  1 
ATOM   651   O OE1 . GLU A 1 83  ? 6.765   67.956  34.741 1.00 183.77 ? 91  GLU A OE1 1 
ATOM   652   O OE2 . GLU A 1 83  ? 6.463   66.262  33.332 1.00 98.82  ? 91  GLU A OE2 1 
ATOM   653   N N   . LEU A 1 84  ? 1.314   69.109  36.620 1.00 101.00 ? 92  LEU A N   1 
ATOM   654   C CA  . LEU A 1 84  ? 0.768   70.038  37.587 1.00 87.94  ? 92  LEU A CA  1 
ATOM   655   C C   . LEU A 1 84  ? -0.405  69.406  38.317 1.00 90.54  ? 92  LEU A C   1 
ATOM   656   O O   . LEU A 1 84  ? -0.364  69.342  39.545 1.00 80.73  ? 92  LEU A O   1 
ATOM   657   C CB  . LEU A 1 84  ? 0.336   71.334  36.911 1.00 69.85  ? 92  LEU A CB  1 
ATOM   658   C CG  . LEU A 1 84  ? -0.377  72.337  37.830 1.00 60.38  ? 92  LEU A CG  1 
ATOM   659   C CD1 . LEU A 1 84  ? 0.084   72.427  39.291 1.00 67.49  ? 92  LEU A CD1 1 
ATOM   660   C CD2 . LEU A 1 84  ? -0.228  73.734  37.237 1.00 43.39  ? 92  LEU A CD2 1 
ATOM   661   N N   . GLU A 1 85  ? -1.434  68.968  37.577 1.00 83.43  ? 93  GLU A N   1 
ATOM   662   C CA  . GLU A 1 85  ? -2.626  68.399  38.204 1.00 87.76  ? 93  GLU A CA  1 
ATOM   663   C C   . GLU A 1 85  ? -2.233  67.222  39.100 1.00 84.44  ? 93  GLU A C   1 
ATOM   664   O O   . GLU A 1 85  ? -2.657  67.109  40.253 1.00 75.58  ? 93  GLU A O   1 
ATOM   665   C CB  . GLU A 1 85  ? -3.651  67.959  37.155 1.00 80.16  ? 93  GLU A CB  1 
ATOM   666   C CG  . GLU A 1 85  ? -4.900  67.297  37.729 1.00 66.35  ? 93  GLU A CG  1 
ATOM   667   C CD  . GLU A 1 85  ? -6.194  67.524  36.925 1.00 94.60  ? 93  GLU A CD  1 
ATOM   668   O OE1 . GLU A 1 85  ? -6.216  68.010  35.745 1.00 91.54  ? 93  GLU A OE1 1 
ATOM   669   O OE2 . GLU A 1 85  ? -7.251  67.333  37.601 1.00 79.45  ? 93  GLU A OE2 1 
ATOM   670   N N   . THR A 1 86  ? -1.380  66.352  38.559 1.00 88.40  ? 94  THR A N   1 
ATOM   671   C CA  . THR A 1 86  ? -0.988  65.183  39.311 1.00 88.01  ? 94  THR A CA  1 
ATOM   672   C C   . THR A 1 86  ? -0.199  65.621  40.538 1.00 91.29  ? 94  THR A C   1 
ATOM   673   O O   . THR A 1 86  ? -0.477  65.149  41.634 1.00 73.45  ? 94  THR A O   1 
ATOM   674   C CB  . THR A 1 86  ? -0.262  64.154  38.455 1.00 80.12  ? 94  THR A CB  1 
ATOM   675   O OG1 . THR A 1 86  ? -1.130  63.754  37.400 1.00 62.09  ? 94  THR A OG1 1 
ATOM   676   C CG2 . THR A 1 86  ? -0.213  62.852  39.222 1.00 63.05  ? 94  THR A CG2 1 
ATOM   677   N N   . LEU A 1 87  ? 0.749   66.550  40.356 1.00 88.18  ? 95  LEU A N   1 
ATOM   678   C CA  . LEU A 1 87  ? 1.524   67.103  41.465 1.00 76.95  ? 95  LEU A CA  1 
ATOM   679   C C   . LEU A 1 87  ? 0.553   67.587  42.536 1.00 80.71  ? 95  LEU A C   1 
ATOM   680   O O   . LEU A 1 87  ? 0.689   67.231  43.708 1.00 74.04  ? 95  LEU A O   1 
ATOM   681   C CB  . LEU A 1 87  ? 2.472   68.228  41.034 1.00 62.01  ? 95  LEU A CB  1 
ATOM   682   C CG  . LEU A 1 87  ? 3.185   69.027  42.131 1.00 66.53  ? 95  LEU A CG  1 
ATOM   683   C CD1 . LEU A 1 87  ? 4.100   68.209  43.004 1.00 81.28  ? 95  LEU A CD1 1 
ATOM   684   C CD2 . LEU A 1 87  ? 4.013   70.108  41.507 1.00 75.35  ? 95  LEU A CD2 1 
ATOM   685   N N   . CYS A 1 88  ? -0.440  68.381  42.113 1.00 69.62  ? 96  CYS A N   1 
ATOM   686   C CA  . CYS A 1 88  ? -1.392  68.945  43.051 1.00 73.35  ? 96  CYS A CA  1 
ATOM   687   C C   . CYS A 1 88  ? -2.073  67.847  43.863 1.00 68.32  ? 96  CYS A C   1 
ATOM   688   O O   . CYS A 1 88  ? -2.141  67.924  45.100 1.00 55.14  ? 96  CYS A O   1 
ATOM   689   C CB  . CYS A 1 88  ? -2.481  69.753  42.373 1.00 69.74  ? 96  CYS A CB  1 
ATOM   690   S SG  . CYS A 1 88  ? -3.198  70.923  43.564 1.00 97.67  ? 96  CYS A SG  1 
ATOM   691   N N   . GLN A 1 89  ? -2.572  66.826  43.164 1.00 61.35  ? 97  GLN A N   1 
ATOM   692   C CA  . GLN A 1 89  ? -3.269  65.725  43.815 1.00 67.24  ? 97  GLN A CA  1 
ATOM   693   C C   . GLN A 1 89  ? -2.350  65.029  44.812 1.00 76.86  ? 97  GLN A C   1 
ATOM   694   O O   . GLN A 1 89  ? -2.793  64.689  45.917 1.00 82.50  ? 97  GLN A O   1 
ATOM   695   C CB  . GLN A 1 89  ? -3.768  64.709  42.795 1.00 65.71  ? 97  GLN A CB  1 
ATOM   696   C CG  . GLN A 1 89  ? -4.898  65.267  41.946 1.00 75.73  ? 97  GLN A CG  1 
ATOM   697   C CD  . GLN A 1 89  ? -5.084  64.544  40.639 1.00 91.64  ? 97  GLN A CD  1 
ATOM   698   O OE1 . GLN A 1 89  ? -4.197  63.807  40.194 1.00 74.92  ? 97  GLN A OE1 1 
ATOM   699   N NE2 . GLN A 1 89  ? -6.227  64.809  40.010 1.00 130.23 ? 97  GLN A NE2 1 
ATOM   700   N N   . LYS A 1 90  ? -1.091  64.806  44.388 1.00 61.04  ? 98  LYS A N   1 
ATOM   701   C CA  . LYS A 1 90  ? -0.099  64.154  45.226 1.00 84.12  ? 98  LYS A CA  1 
ATOM   702   C C   . LYS A 1 90  ? 0.057   64.955  46.522 1.00 104.28 ? 98  LYS A C   1 
ATOM   703   O O   . LYS A 1 90  ? -0.004  64.386  47.617 1.00 97.70  ? 98  LYS A O   1 
ATOM   704   C CB  . LYS A 1 90  ? 1.195   63.938  44.436 1.00 94.92  ? 98  LYS A CB  1 
ATOM   705   C CG  . LYS A 1 90  ? 2.380   63.411  45.233 1.00 130.66 ? 98  LYS A CG  1 
ATOM   706   C CD  . LYS A 1 90  ? 3.547   63.055  44.298 1.00 152.86 ? 98  LYS A CD  1 
ATOM   707   C CE  . LYS A 1 90  ? 4.431   64.155  43.734 1.00 128.30 ? 98  LYS A CE  1 
ATOM   708   N NZ  . LYS A 1 90  ? 5.120   64.813  44.860 1.00 88.15  ? 98  LYS A NZ  1 
ATOM   709   N N   . ARG A 1 91  ? 0.223   66.283  46.386 1.00 91.38  ? 99  ARG A N   1 
ATOM   710   C CA  . ARG A 1 91  ? 0.449   67.165  47.523 1.00 95.66  ? 99  ARG A CA  1 
ATOM   711   C C   . ARG A 1 91  ? -0.779  67.195  48.432 1.00 104.18 ? 99  ARG A C   1 
ATOM   712   O O   . ARG A 1 91  ? -0.676  67.226  49.663 1.00 116.12 ? 99  ARG A O   1 
ATOM   713   C CB  . ARG A 1 91  ? 0.765   68.588  47.058 1.00 76.37  ? 99  ARG A CB  1 
ATOM   714   C CG  . ARG A 1 91  ? 2.127   68.703  46.404 1.00 91.26  ? 99  ARG A CG  1 
ATOM   715   C CD  . ARG A 1 91  ? 2.422   70.146  46.091 1.00 102.07 ? 99  ARG A CD  1 
ATOM   716   N NE  . ARG A 1 91  ? 3.782   70.308  45.572 1.00 90.31  ? 99  ARG A NE  1 
ATOM   717   C CZ  . ARG A 1 91  ? 4.286   71.467  45.207 1.00 94.24  ? 99  ARG A CZ  1 
ATOM   718   N NH1 . ARG A 1 91  ? 3.539   72.540  45.275 1.00 101.95 ? 99  ARG A NH1 1 
ATOM   719   N NH2 . ARG A 1 91  ? 5.525   71.553  44.768 1.00 123.95 ? 99  ARG A NH2 1 
ATOM   720   N N   . ALA A 1 92  ? -1.957  67.185  47.806 1.00 74.03  ? 100 ALA A N   1 
ATOM   721   C CA  . ALA A 1 92  ? -3.174  67.231  48.584 1.00 76.29  ? 100 ALA A CA  1 
ATOM   722   C C   . ALA A 1 92  ? -3.254  65.994  49.487 1.00 80.56  ? 100 ALA A C   1 
ATOM   723   O O   . ALA A 1 92  ? -3.586  66.130  50.667 1.00 64.70  ? 100 ALA A O   1 
ATOM   724   C CB  . ALA A 1 92  ? -4.348  67.351  47.653 1.00 73.13  ? 100 ALA A CB  1 
ATOM   725   N N   . LEU A 1 93  ? -2.997  64.800  48.922 1.00 63.38  ? 101 LEU A N   1 
ATOM   726   C CA  . LEU A 1 93  ? -3.083  63.582  49.708 1.00 98.19  ? 101 LEU A CA  1 
ATOM   727   C C   . LEU A 1 93  ? -2.012  63.584  50.804 1.00 97.59  ? 101 LEU A C   1 
ATOM   728   O O   . LEU A 1 93  ? -2.273  63.083  51.912 1.00 65.18  ? 101 LEU A O   1 
ATOM   729   C CB  . LEU A 1 93  ? -3.003  62.356  48.800 1.00 101.45 ? 101 LEU A CB  1 
ATOM   730   C CG  . LEU A 1 93  ? -4.142  62.191  47.791 1.00 97.38  ? 101 LEU A CG  1 
ATOM   731   C CD1 . LEU A 1 93  ? -3.791  60.893  47.109 1.00 119.64 ? 101 LEU A CD1 1 
ATOM   732   C CD2 . LEU A 1 93  ? -5.542  62.039  48.367 1.00 96.03  ? 101 LEU A CD2 1 
ATOM   733   N N   . GLN A 1 94  ? -0.835  64.163  50.492 1.00 81.14  ? 102 GLN A N   1 
ATOM   734   C CA  . GLN A 1 94  ? 0.252   64.266  51.464 1.00 85.79  ? 102 GLN A CA  1 
ATOM   735   C C   . GLN A 1 94  ? -0.210  65.134  52.644 1.00 84.81  ? 102 GLN A C   1 
ATOM   736   O O   . GLN A 1 94  ? -0.282  64.696  53.823 1.00 56.85  ? 102 GLN A O   1 
ATOM   737   C CB  . GLN A 1 94  ? 1.543   64.948  50.994 1.00 60.80  ? 102 GLN A CB  1 
ATOM   738   C CG  . GLN A 1 94  ? 2.348   64.192  49.951 1.00 111.92 ? 102 GLN A CG  1 
ATOM   739   C CD  . GLN A 1 94  ? 3.322   65.077  49.191 1.00 127.80 ? 102 GLN A CD  1 
ATOM   740   O OE1 . GLN A 1 94  ? 3.668   64.833  48.008 1.00 102.38 ? 102 GLN A OE1 1 
ATOM   741   N NE2 . GLN A 1 94  ? 3.762   66.133  49.872 1.00 95.85  ? 102 GLN A NE2 1 
ATOM   742   N N   . ALA A 1 95  ? -0.565  66.382  52.300 1.00 65.61  ? 103 ALA A N   1 
ATOM   743   C CA  . ALA A 1 95  ? -0.899  67.385  53.297 1.00 76.68  ? 103 ALA A CA  1 
ATOM   744   C C   . ALA A 1 95  ? -1.929  66.831  54.295 1.00 89.42  ? 103 ALA A C   1 
ATOM   745   O O   . ALA A 1 95  ? -1.928  67.222  55.472 1.00 65.31  ? 103 ALA A O   1 
ATOM   746   C CB  . ALA A 1 95  ? -1.408  68.608  52.577 1.00 53.63  ? 103 ALA A CB  1 
ATOM   747   N N   . TYR A 1 96  ? -2.793  65.911  53.816 1.00 81.90  ? 104 TYR A N   1 
ATOM   748   C CA  . TYR A 1 96  ? -3.831  65.366  54.681 1.00 73.06  ? 104 TYR A CA  1 
ATOM   749   C C   . TYR A 1 96  ? -3.500  63.983  55.191 1.00 72.65  ? 104 TYR A C   1 
ATOM   750   O O   . TYR A 1 96  ? -4.378  63.411  55.847 1.00 78.97  ? 104 TYR A O   1 
ATOM   751   C CB  . TYR A 1 96  ? -5.275  65.435  54.181 1.00 77.36  ? 104 TYR A CB  1 
ATOM   752   C CG  . TYR A 1 96  ? -5.704  66.897  54.145 1.00 84.91  ? 104 TYR A CG  1 
ATOM   753   C CD1 . TYR A 1 96  ? -6.166  67.522  55.301 1.00 74.38  ? 104 TYR A CD1 1 
ATOM   754   C CD2 . TYR A 1 96  ? -5.552  67.651  52.993 1.00 70.27  ? 104 TYR A CD2 1 
ATOM   755   C CE1 . TYR A 1 96  ? -6.483  68.861  55.307 1.00 79.32  ? 104 TYR A CE1 1 
ATOM   756   C CE2 . TYR A 1 96  ? -5.873  68.995  52.999 1.00 86.86  ? 104 TYR A CE2 1 
ATOM   757   C CZ  . TYR A 1 96  ? -6.329  69.606  54.151 1.00 94.39  ? 104 TYR A CZ  1 
ATOM   758   O OH  . TYR A 1 96  ? -6.720  70.921  54.087 1.00 102.41 ? 104 TYR A OH  1 
ATOM   759   N N   . LYS A 1 97  ? -2.259  63.512  54.922 1.00 68.53  ? 105 LYS A N   1 
ATOM   760   C CA  . LYS A 1 97  ? -1.742  62.243  55.440 1.00 63.83  ? 105 LYS A CA  1 
ATOM   761   C C   . LYS A 1 97  ? -2.764  61.160  55.108 1.00 56.98  ? 105 LYS A C   1 
ATOM   762   O O   . LYS A 1 97  ? -3.224  60.434  55.978 1.00 66.98  ? 105 LYS A O   1 
ATOM   763   C CB  . LYS A 1 97  ? -1.338  62.309  56.929 1.00 64.28  ? 105 LYS A CB  1 
ATOM   764   C CG  . LYS A 1 97  ? -0.014  63.082  57.103 1.00 86.76  ? 105 LYS A CG  1 
ATOM   765   C CD  . LYS A 1 97  ? 0.179   64.486  57.692 1.00 80.85  ? 105 LYS A CD  1 
ATOM   766   C CE  . LYS A 1 97  ? 1.636   64.879  57.713 1.00 93.61  ? 105 LYS A CE  1 
ATOM   767   N NZ  . LYS A 1 97  ? 2.439   64.484  56.529 1.00 64.71  ? 105 LYS A NZ  1 
ATOM   768   N N   . LEU A 1 98  ? -3.158  61.108  53.835 1.00 55.83  ? 106 LEU A N   1 
ATOM   769   C CA  . LEU A 1 98  ? -4.124  60.108  53.425 1.00 62.24  ? 106 LEU A CA  1 
ATOM   770   C C   . LEU A 1 98  ? -3.425  58.993  52.668 1.00 82.29  ? 106 LEU A C   1 
ATOM   771   O O   . LEU A 1 98  ? -2.575  59.275  51.767 1.00 58.22  ? 106 LEU A O   1 
ATOM   772   C CB  . LEU A 1 98  ? -5.078  60.823  52.471 1.00 75.74  ? 106 LEU A CB  1 
ATOM   773   C CG  . LEU A 1 98  ? -5.883  61.958  53.072 1.00 78.66  ? 106 LEU A CG  1 
ATOM   774   C CD1 . LEU A 1 98  ? -6.876  62.400  52.060 1.00 72.52  ? 106 LEU A CD1 1 
ATOM   775   C CD2 . LEU A 1 98  ? -6.564  61.494  54.299 1.00 60.90  ? 106 LEU A CD2 1 
ATOM   776   N N   . ASP A 1 99  ? -3.905  57.766  52.962 1.00 77.06  ? 107 ASP A N   1 
ATOM   777   C CA  . ASP A 1 99  ? -3.416  56.585  52.253 1.00 101.63 ? 107 ASP A CA  1 
ATOM   778   C C   . ASP A 1 99  ? -3.795  56.601  50.762 1.00 82.85  ? 107 ASP A C   1 
ATOM   779   O O   . ASP A 1 99  ? -4.981  56.541  50.441 1.00 95.15  ? 107 ASP A O   1 
ATOM   780   C CB  . ASP A 1 99  ? -3.934  55.304  52.889 1.00 84.87  ? 107 ASP A CB  1 
ATOM   781   C CG  . ASP A 1 99  ? -3.354  54.112  52.162 1.00 85.22  ? 107 ASP A CG  1 
ATOM   782   O OD1 . ASP A 1 99  ? -2.154  53.929  52.379 1.00 78.10  ? 107 ASP A OD1 1 
ATOM   783   O OD2 . ASP A 1 99  ? -4.034  53.605  51.209 1.00 103.18 ? 107 ASP A OD2 1 
ATOM   784   N N   . PRO A 1 100 ? -2.851  56.752  49.800 1.00 69.95  ? 108 PRO A N   1 
ATOM   785   C CA  . PRO A 1 100 ? -3.246  56.995  48.399 1.00 83.40  ? 108 PRO A CA  1 
ATOM   786   C C   . PRO A 1 100 ? -4.011  55.832  47.772 1.00 80.85  ? 108 PRO A C   1 
ATOM   787   O O   . PRO A 1 100 ? -4.606  55.996  46.709 1.00 101.03 ? 108 PRO A O   1 
ATOM   788   C CB  . PRO A 1 100 ? -1.935  57.300  47.655 1.00 73.03  ? 108 PRO A CB  1 
ATOM   789   C CG  . PRO A 1 100 ? -0.994  57.637  48.799 1.00 92.67  ? 108 PRO A CG  1 
ATOM   790   C CD  . PRO A 1 100 ? -1.398  56.741  50.011 1.00 77.16  ? 108 PRO A CD  1 
ATOM   791   N N   . GLN A 1 101 ? -3.968  54.663  48.432 1.00 81.70  ? 109 GLN A N   1 
ATOM   792   C CA  . GLN A 1 101 ? -4.735  53.542  47.923 1.00 98.33  ? 109 GLN A CA  1 
ATOM   793   C C   . GLN A 1 101 ? -6.152  53.584  48.468 1.00 81.54  ? 109 GLN A C   1 
ATOM   794   O O   . GLN A 1 101 ? -7.052  52.938  47.939 1.00 90.25  ? 109 GLN A O   1 
ATOM   795   C CB  . GLN A 1 101 ? -4.032  52.197  47.837 1.00 96.07  ? 109 GLN A CB  1 
ATOM   796   C CG  . GLN A 1 101 ? -3.615  52.008  46.383 1.00 92.27  ? 109 GLN A CG  1 
ATOM   797   C CD  . GLN A 1 101 ? -2.875  50.727  46.199 1.00 115.36 ? 109 GLN A CD  1 
ATOM   798   O OE1 . GLN A 1 101 ? -2.297  50.205  47.162 1.00 121.06 ? 109 GLN A OE1 1 
ATOM   799   N NE2 . GLN A 1 101 ? -2.879  50.252  44.961 1.00 109.98 ? 109 GLN A NE2 1 
ATOM   800   N N   . CYS A 1 102 ? -6.353  54.401  49.488 1.00 68.32  ? 110 CYS A N   1 
ATOM   801   C CA  . CYS A 1 102 ? -7.704  54.457  50.030 1.00 82.73  ? 110 CYS A CA  1 
ATOM   802   C C   . CYS A 1 102 ? -8.357  55.821  49.903 1.00 104.56 ? 110 CYS A C   1 
ATOM   803   O O   . CYS A 1 102 ? -9.462  55.989  50.406 1.00 99.78  ? 110 CYS A O   1 
ATOM   804   C CB  . CYS A 1 102 ? -7.758  54.282  51.526 1.00 59.17  ? 110 CYS A CB  1 
ATOM   805   S SG  . CYS A 1 102 ? -7.228  52.605  51.887 1.00 77.78  ? 110 CYS A SG  1 
ATOM   806   N N   . TRP A 1 103 ? -7.607  56.766  49.342 1.00 86.04  ? 111 TRP A N   1 
ATOM   807   C CA  . TRP A 1 103 ? -8.117  58.082  49.050 1.00 82.61  ? 111 TRP A CA  1 
ATOM   808   C C   . TRP A 1 103 ? -7.625  58.554  47.700 1.00 93.46  ? 111 TRP A C   1 
ATOM   809   O O   . TRP A 1 103 ? -6.456  58.360  47.355 1.00 114.80 ? 111 TRP A O   1 
ATOM   810   C CB  . TRP A 1 103 ? -7.684  59.077  50.136 1.00 71.37  ? 111 TRP A CB  1 
ATOM   811   C CG  . TRP A 1 103 ? -8.462  58.957  51.413 1.00 82.25  ? 111 TRP A CG  1 
ATOM   812   C CD1 . TRP A 1 103 ? -8.050  58.280  52.505 1.00 81.79  ? 111 TRP A CD1 1 
ATOM   813   C CD2 . TRP A 1 103 ? -9.765  59.523  51.728 1.00 114.04 ? 111 TRP A CD2 1 
ATOM   814   N NE1 . TRP A 1 103 ? -8.997  58.386  53.490 1.00 109.00 ? 111 TRP A NE1 1 
ATOM   815   C CE2 . TRP A 1 103 ? -10.058 59.124  53.050 1.00 100.82 ? 111 TRP A CE2 1 
ATOM   816   C CE3 . TRP A 1 103 ? -10.717 60.298  51.034 1.00 90.39  ? 111 TRP A CE3 1 
ATOM   817   C CZ2 . TRP A 1 103 ? -11.232 59.482  53.701 1.00 95.23  ? 111 TRP A CZ2 1 
ATOM   818   C CZ3 . TRP A 1 103 ? -11.884 60.638  51.681 1.00 95.08  ? 111 TRP A CZ3 1 
ATOM   819   C CH2 . TRP A 1 103 ? -12.139 60.230  52.987 1.00 122.01 ? 111 TRP A CH2 1 
ATOM   820   N N   . GLY A 1 104 ? -8.545  59.199  46.984 1.00 94.96  ? 112 GLY A N   1 
ATOM   821   C CA  . GLY A 1 104 ? -8.174  60.017  45.844 1.00 109.81 ? 112 GLY A CA  1 
ATOM   822   C C   . GLY A 1 104 ? -8.665  61.443  46.057 1.00 100.04 ? 112 GLY A C   1 
ATOM   823   O O   . GLY A 1 104 ? -9.417  61.730  46.974 1.00 107.66 ? 112 GLY A O   1 
ATOM   824   N N   . VAL A 1 105 ? -8.257  62.353  45.184 1.00 83.88  ? 113 VAL A N   1 
ATOM   825   C CA  . VAL A 1 105 ? -8.717  63.729  45.293 1.00 83.33  ? 113 VAL A CA  1 
ATOM   826   C C   . VAL A 1 105 ? -8.830  64.330  43.892 1.00 82.95  ? 113 VAL A C   1 
ATOM   827   O O   . VAL A 1 105 ? -7.950  64.139  43.060 1.00 126.08 ? 113 VAL A O   1 
ATOM   828   C CB  . VAL A 1 105 ? -7.747  64.558  46.147 1.00 87.08  ? 113 VAL A CB  1 
ATOM   829   C CG1 . VAL A 1 105 ? -6.342  64.520  45.575 1.00 105.13 ? 113 VAL A CG1 1 
ATOM   830   C CG2 . VAL A 1 105 ? -8.157  66.030  46.250 1.00 88.72  ? 113 VAL A CG2 1 
ATOM   831   N N   . ASN A 1 106 ? -9.923  65.056  43.620 1.00 60.23  ? 114 ASN A N   1 
ATOM   832   C CA  . ASN A 1 106 ? -9.979  65.819  42.381 1.00 58.57  ? 114 ASN A CA  1 
ATOM   833   C C   . ASN A 1 106 ? -9.800  67.294  42.746 1.00 75.48  ? 114 ASN A C   1 
ATOM   834   O O   . ASN A 1 106 ? -10.407 67.809  43.697 1.00 91.54  ? 114 ASN A O   1 
ATOM   835   C CB  . ASN A 1 106 ? -11.026 65.313  41.402 1.00 60.40  ? 114 ASN A CB  1 
ATOM   836   C CG  . ASN A 1 106 ? -11.889 66.349  40.696 1.00 88.18  ? 114 ASN A CG  1 
ATOM   837   O OD1 . ASN A 1 106 ? -11.673 67.581  40.677 1.00 56.62  ? 114 ASN A OD1 1 
ATOM   838   N ND2 . ASN A 1 106 ? -12.902 65.801  40.048 1.00 98.99  ? 114 ASN A ND2 1 
ATOM   839   N N   . VAL A 1 107 ? -8.944  67.970  41.969 1.00 62.84  ? 115 VAL A N   1 
ATOM   840   C CA  . VAL A 1 107 ? -8.542  69.331  42.312 1.00 61.84  ? 115 VAL A CA  1 
ATOM   841   C C   . VAL A 1 107 ? -9.087  70.334  41.288 1.00 73.52  ? 115 VAL A C   1 
ATOM   842   O O   . VAL A 1 107 ? -8.572  71.435  41.163 1.00 80.39  ? 115 VAL A O   1 
ATOM   843   C CB  . VAL A 1 107 ? -6.999  69.403  42.364 1.00 71.28  ? 115 VAL A CB  1 
ATOM   844   C CG1 . VAL A 1 107 ? -6.441  68.690  43.593 1.00 86.14  ? 115 VAL A CG1 1 
ATOM   845   C CG2 . VAL A 1 107 ? -6.351  68.867  41.088 1.00 78.32  ? 115 VAL A CG2 1 
ATOM   846   N N   . GLN A 1 108 ? -10.121 69.977  40.518 1.00 77.39  ? 116 GLN A N   1 
ATOM   847   C CA  . GLN A 1 108 ? -10.610 70.868  39.475 1.00 72.22  ? 116 GLN A CA  1 
ATOM   848   C C   . GLN A 1 108 ? -11.685 71.848  39.946 1.00 81.12  ? 116 GLN A C   1 
ATOM   849   O O   . GLN A 1 108 ? -11.921 72.856  39.285 1.00 84.43  ? 116 GLN A O   1 
ATOM   850   C CB  . GLN A 1 108 ? -11.128 70.083  38.278 1.00 65.30  ? 116 GLN A CB  1 
ATOM   851   C CG  . GLN A 1 108 ? -9.976  69.692  37.370 1.00 78.02  ? 116 GLN A CG  1 
ATOM   852   C CD  . GLN A 1 108 ? -10.391 68.979  36.109 1.00 93.65  ? 116 GLN A CD  1 
ATOM   853   O OE1 . GLN A 1 108 ? -11.284 69.439  35.355 1.00 100.95 ? 116 GLN A OE1 1 
ATOM   854   N NE2 . GLN A 1 108 ? -9.616  67.919  35.864 1.00 61.52  ? 116 GLN A NE2 1 
ATOM   855   N N   . PRO A 1 109 ? -12.425 71.588  41.050 1.00 81.06  ? 117 PRO A N   1 
ATOM   856   C CA  . PRO A 1 109 ? -13.511 72.491  41.435 1.00 76.97  ? 117 PRO A CA  1 
ATOM   857   C C   . PRO A 1 109 ? -13.070 73.949  41.358 1.00 84.03  ? 117 PRO A C   1 
ATOM   858   O O   . PRO A 1 109 ? -12.024 74.332  41.909 1.00 115.61 ? 117 PRO A O   1 
ATOM   859   C CB  . PRO A 1 109 ? -13.773 72.017  42.857 1.00 73.26  ? 117 PRO A CB  1 
ATOM   860   C CG  . PRO A 1 109 ? -13.506 70.529  42.792 1.00 88.91  ? 117 PRO A CG  1 
ATOM   861   C CD  . PRO A 1 109 ? -12.242 70.469  41.990 1.00 84.87  ? 117 PRO A CD  1 
ATOM   862   N N   . TYR A 1 110 ? -13.901 74.763  40.694 1.00 62.64  ? 118 TYR A N   1 
ATOM   863   C CA  . TYR A 1 110 ? -13.615 76.183  40.535 1.00 60.82  ? 118 TYR A CA  1 
ATOM   864   C C   . TYR A 1 110 ? -13.609 76.933  41.882 1.00 67.49  ? 118 TYR A C   1 
ATOM   865   O O   . TYR A 1 110 ? -12.891 77.921  42.043 1.00 62.61  ? 118 TYR A O   1 
ATOM   866   C CB  . TYR A 1 110 ? -14.741 76.728  39.674 1.00 51.56  ? 118 TYR A CB  1 
ATOM   867   C CG  . TYR A 1 110 ? -14.680 76.252  38.246 1.00 68.03  ? 118 TYR A CG  1 
ATOM   868   C CD1 . TYR A 1 110 ? -13.465 75.986  37.632 1.00 75.44  ? 118 TYR A CD1 1 
ATOM   869   C CD2 . TYR A 1 110 ? -15.841 76.139  37.483 1.00 86.90  ? 118 TYR A CD2 1 
ATOM   870   C CE1 . TYR A 1 110 ? -13.421 75.593  36.301 1.00 98.70  ? 118 TYR A CE1 1 
ATOM   871   C CE2 . TYR A 1 110 ? -15.808 75.752  36.151 1.00 102.05 ? 118 TYR A CE2 1 
ATOM   872   C CZ  . TYR A 1 110 ? -14.589 75.455  35.568 1.00 100.52 ? 118 TYR A CZ  1 
ATOM   873   O OH  . TYR A 1 110 ? -14.517 75.051  34.273 1.00 122.68 ? 118 TYR A OH  1 
ATOM   874   N N   . SER A 1 111 ? -14.442 76.487  42.824 1.00 60.47  ? 119 SER A N   1 
ATOM   875   C CA  . SER A 1 111 ? -14.467 77.025  44.166 1.00 76.58  ? 119 SER A CA  1 
ATOM   876   C C   . SER A 1 111 ? -15.164 76.002  45.064 1.00 87.73  ? 119 SER A C   1 
ATOM   877   O O   . SER A 1 111 ? -15.399 74.882  44.636 1.00 78.68  ? 119 SER A O   1 
ATOM   878   C CB  . SER A 1 111 ? -15.074 78.411  44.268 1.00 80.35  ? 119 SER A CB  1 
ATOM   879   O OG  . SER A 1 111 ? -14.625 79.065  45.474 1.00 71.49  ? 119 SER A OG  1 
ATOM   880   N N   . GLY A 1 112 ? -15.518 76.395  46.284 1.00 85.17  ? 120 GLY A N   1 
ATOM   881   C CA  . GLY A 1 112 ? -16.046 75.444  47.237 1.00 85.63  ? 120 GLY A CA  1 
ATOM   882   C C   . GLY A 1 112 ? -17.447 74.984  46.842 1.00 75.62  ? 120 GLY A C   1 
ATOM   883   O O   . GLY A 1 112 ? -17.725 73.786  46.755 1.00 62.64  ? 120 GLY A O   1 
ATOM   884   N N   . SER A 1 113 ? -18.363 75.941  46.661 1.00 58.88  ? 121 SER A N   1 
ATOM   885   C CA  . SER A 1 113 ? -19.726 75.587  46.331 1.00 59.03  ? 121 SER A CA  1 
ATOM   886   C C   . SER A 1 113 ? -19.739 74.693  45.080 1.00 74.66  ? 121 SER A C   1 
ATOM   887   O O   . SER A 1 113 ? -20.479 73.714  45.045 1.00 63.17  ? 121 SER A O   1 
ATOM   888   C CB  . SER A 1 113 ? -20.592 76.804  46.149 1.00 66.21  ? 121 SER A CB  1 
ATOM   889   O OG  . SER A 1 113 ? -20.389 77.751  47.170 1.00 62.75  ? 121 SER A OG  1 
ATOM   890   N N   . PRO A 1 114 ? -18.999 74.983  43.970 1.00 69.05  ? 122 PRO A N   1 
ATOM   891   C CA  . PRO A 1 114 ? -18.867 74.006  42.880 1.00 71.46  ? 122 PRO A CA  1 
ATOM   892   C C   . PRO A 1 114 ? -18.472 72.596  43.318 1.00 75.30  ? 122 PRO A C   1 
ATOM   893   O O   . PRO A 1 114 ? -19.011 71.602  42.846 1.00 63.31  ? 122 PRO A O   1 
ATOM   894   C CB  . PRO A 1 114 ? -17.807 74.598  42.028 1.00 60.83  ? 122 PRO A CB  1 
ATOM   895   C CG  . PRO A 1 114 ? -18.126 76.068  42.238 1.00 81.00  ? 122 PRO A CG  1 
ATOM   896   C CD  . PRO A 1 114 ? -18.283 76.239  43.729 1.00 72.21  ? 122 PRO A CD  1 
ATOM   897   N N   . ALA A 1 115 ? -17.558 72.509  44.279 1.00 85.81  ? 123 ALA A N   1 
ATOM   898   C CA  . ALA A 1 115 ? -17.106 71.202  44.726 1.00 81.31  ? 123 ALA A CA  1 
ATOM   899   C C   . ALA A 1 115 ? -18.272 70.414  45.341 1.00 76.37  ? 123 ALA A C   1 
ATOM   900   O O   . ALA A 1 115 ? -18.477 69.249  45.002 1.00 60.69  ? 123 ALA A O   1 
ATOM   901   C CB  . ALA A 1 115 ? -15.892 71.356  45.637 1.00 43.64  ? 123 ALA A CB  1 
ATOM   902   N N   . ASN A 1 116 ? -19.045 71.078  46.214 1.00 54.74  ? 124 ASN A N   1 
ATOM   903   C CA  . ASN A 1 116 ? -20.082 70.370  46.938 1.00 74.17  ? 124 ASN A CA  1 
ATOM   904   C C   . ASN A 1 116 ? -21.152 69.960  45.920 1.00 76.95  ? 124 ASN A C   1 
ATOM   905   O O   . ASN A 1 116 ? -21.680 68.834  45.937 1.00 60.02  ? 124 ASN A O   1 
ATOM   906   C CB  . ASN A 1 116 ? -20.737 71.223  48.019 1.00 81.89  ? 124 ASN A CB  1 
ATOM   907   C CG  . ASN A 1 116 ? -19.869 71.543  49.198 1.00 100.49 ? 124 ASN A CG  1 
ATOM   908   O OD1 . ASN A 1 116 ? -18.661 71.283  49.230 1.00 93.00  ? 124 ASN A OD1 1 
ATOM   909   N ND2 . ASN A 1 116 ? -20.490 72.148  50.188 1.00 156.55 ? 124 ASN A ND2 1 
ATOM   910   N N   . PHE A 1 117 ? -21.475 70.893  45.010 1.00 53.16  ? 125 PHE A N   1 
ATOM   911   C CA  . PHE A 1 117 ? -22.548 70.622  44.065 1.00 66.51  ? 125 PHE A CA  1 
ATOM   912   C C   . PHE A 1 117 ? -22.161 69.379  43.265 1.00 69.55  ? 125 PHE A C   1 
ATOM   913   O O   . PHE A 1 117 ? -23.037 68.549  42.966 1.00 58.25  ? 125 PHE A O   1 
ATOM   914   C CB  . PHE A 1 117 ? -22.832 71.857  43.204 1.00 59.12  ? 125 PHE A CB  1 
ATOM   915   C CG  . PHE A 1 117 ? -24.092 71.691  42.385 1.00 50.19  ? 125 PHE A CG  1 
ATOM   916   C CD1 . PHE A 1 117 ? -25.310 72.087  42.947 1.00 50.91  ? 125 PHE A CD1 1 
ATOM   917   C CD2 . PHE A 1 117 ? -24.066 71.072  41.125 1.00 51.66  ? 125 PHE A CD2 1 
ATOM   918   C CE1 . PHE A 1 117 ? -26.504 71.938  42.231 1.00 63.53  ? 125 PHE A CE1 1 
ATOM   919   C CE2 . PHE A 1 117 ? -25.251 70.939  40.394 1.00 63.78  ? 125 PHE A CE2 1 
ATOM   920   C CZ  . PHE A 1 117 ? -26.470 71.404  40.943 1.00 74.47  ? 125 PHE A CZ  1 
ATOM   921   N N   . ALA A 1 118 ? -20.845 69.281  42.957 1.00 57.88  ? 126 ALA A N   1 
ATOM   922   C CA  . ALA A 1 118 ? -20.335 68.165  42.184 1.00 68.96  ? 126 ALA A CA  1 
ATOM   923   C C   . ALA A 1 118 ? -20.498 66.848  42.971 1.00 74.01  ? 126 ALA A C   1 
ATOM   924   O O   . ALA A 1 118 ? -20.897 65.807  42.421 1.00 55.46  ? 126 ALA A O   1 
ATOM   925   C CB  . ALA A 1 118 ? -18.896 68.421  41.833 1.00 52.45  ? 126 ALA A CB  1 
ATOM   926   N N   . VAL A 1 119 ? -20.183 66.889  44.270 1.00 46.37  ? 127 VAL A N   1 
ATOM   927   C CA  . VAL A 1 119 ? -20.352 65.694  45.075 1.00 56.42  ? 127 VAL A CA  1 
ATOM   928   C C   . VAL A 1 119 ? -21.822 65.238  45.084 1.00 74.23  ? 127 VAL A C   1 
ATOM   929   O O   . VAL A 1 119 ? -22.074 64.009  45.019 1.00 54.50  ? 127 VAL A O   1 
ATOM   930   C CB  . VAL A 1 119 ? -19.791 65.874  46.510 1.00 55.65  ? 127 VAL A CB  1 
ATOM   931   C CG1 . VAL A 1 119 ? -20.104 64.697  47.441 1.00 51.05  ? 127 VAL A CG1 1 
ATOM   932   C CG2 . VAL A 1 119 ? -18.302 66.161  46.459 1.00 69.59  ? 127 VAL A CG2 1 
ATOM   933   N N   . TYR A 1 120 ? -22.771 66.207  45.217 1.00 65.11  ? 128 TYR A N   1 
ATOM   934   C CA  . TYR A 1 120 ? -24.175 65.834  45.302 1.00 71.30  ? 128 TYR A CA  1 
ATOM   935   C C   . TYR A 1 120 ? -24.621 65.277  43.955 1.00 99.28  ? 128 TYR A C   1 
ATOM   936   O O   . TYR A 1 120 ? -25.363 64.286  43.896 1.00 111.50 ? 128 TYR A O   1 
ATOM   937   C CB  . TYR A 1 120 ? -25.020 67.040  45.646 1.00 69.68  ? 128 TYR A CB  1 
ATOM   938   C CG  . TYR A 1 120 ? -24.576 67.873  46.837 1.00 87.82  ? 128 TYR A CG  1 
ATOM   939   C CD1 . TYR A 1 120 ? -24.199 67.273  48.026 1.00 104.41 ? 128 TYR A CD1 1 
ATOM   940   C CD2 . TYR A 1 120 ? -24.603 69.266  46.795 1.00 100.88 ? 128 TYR A CD2 1 
ATOM   941   C CE1 . TYR A 1 120 ? -23.840 68.022  49.136 1.00 92.98  ? 128 TYR A CE1 1 
ATOM   942   C CE2 . TYR A 1 120 ? -24.238 70.029  47.890 1.00 104.39 ? 128 TYR A CE2 1 
ATOM   943   C CZ  . TYR A 1 120 ? -23.830 69.400  49.052 1.00 96.38  ? 128 TYR A CZ  1 
ATOM   944   O OH  . TYR A 1 120 ? -23.451 70.135  50.132 1.00 102.22 ? 128 TYR A OH  1 
ATOM   945   N N   . THR A 1 121 ? -24.097 65.872  42.869 1.00 78.51  ? 129 THR A N   1 
ATOM   946   C CA  . THR A 1 121 ? -24.360 65.385  41.519 1.00 70.27  ? 129 THR A CA  1 
ATOM   947   C C   . THR A 1 121 ? -23.900 63.942  41.368 1.00 64.35  ? 129 THR A C   1 
ATOM   948   O O   . THR A 1 121 ? -24.648 63.162  40.806 1.00 65.89  ? 129 THR A O   1 
ATOM   949   C CB  . THR A 1 121 ? -23.744 66.287  40.451 1.00 58.18  ? 129 THR A CB  1 
ATOM   950   O OG1 . THR A 1 121 ? -24.410 67.563  40.519 1.00 67.32  ? 129 THR A OG1 1 
ATOM   951   C CG2 . THR A 1 121 ? -23.703 65.624  39.092 1.00 35.85  ? 129 THR A CG2 1 
ATOM   952   N N   . ALA A 1 122 ? -22.702 63.621  41.877 1.00 71.60  ? 130 ALA A N   1 
ATOM   953   C CA  . ALA A 1 122 ? -22.107 62.293  41.709 1.00 94.47  ? 130 ALA A CA  1 
ATOM   954   C C   . ALA A 1 122 ? -22.792 61.232  42.565 1.00 83.47  ? 130 ALA A C   1 
ATOM   955   O O   . ALA A 1 122 ? -22.943 60.093  42.129 1.00 68.91  ? 130 ALA A O   1 
ATOM   956   C CB  . ALA A 1 122 ? -20.634 62.294  42.031 1.00 85.99  ? 130 ALA A CB  1 
ATOM   957   N N   . LEU A 1 123 ? -23.159 61.595  43.798 1.00 80.02  ? 131 LEU A N   1 
ATOM   958   C CA  . LEU A 1 123 ? -23.542 60.561  44.739 1.00 78.29  ? 131 LEU A CA  1 
ATOM   959   C C   . LEU A 1 123 ? -25.025 60.617  45.053 1.00 90.43  ? 131 LEU A C   1 
ATOM   960   O O   . LEU A 1 123 ? -25.568 59.588  45.441 1.00 117.82 ? 131 LEU A O   1 
ATOM   961   C CB  . LEU A 1 123 ? -22.704 60.607  46.007 1.00 83.86  ? 131 LEU A CB  1 
ATOM   962   C CG  . LEU A 1 123 ? -21.196 60.662  45.761 1.00 97.81  ? 131 LEU A CG  1 
ATOM   963   C CD1 . LEU A 1 123 ? -20.395 60.786  47.047 1.00 95.79  ? 131 LEU A CD1 1 
ATOM   964   C CD2 . LEU A 1 123 ? -20.911 59.395  44.996 1.00 72.51  ? 131 LEU A CD2 1 
ATOM   965   N N   . VAL A 1 124 ? -25.665 61.785  44.895 1.00 79.35  ? 132 VAL A N   1 
ATOM   966   C CA  . VAL A 1 124 ? -27.018 61.908  45.408 1.00 68.23  ? 132 VAL A CA  1 
ATOM   967   C C   . VAL A 1 124 ? -28.014 61.744  44.281 1.00 89.94  ? 132 VAL A C   1 
ATOM   968   O O   . VAL A 1 124 ? -29.054 61.111  44.503 1.00 114.85 ? 132 VAL A O   1 
ATOM   969   C CB  . VAL A 1 124 ? -27.280 63.200  46.177 1.00 54.08  ? 132 VAL A CB  1 
ATOM   970   C CG1 . VAL A 1 124 ? -28.713 63.254  46.723 1.00 50.76  ? 132 VAL A CG1 1 
ATOM   971   C CG2 . VAL A 1 124 ? -26.283 63.268  47.327 1.00 66.53  ? 132 VAL A CG2 1 
ATOM   972   N N   . GLU A 1 125 ? -27.678 62.321  43.111 1.00 93.32  ? 133 GLU A N   1 
ATOM   973   C CA  . GLU A 1 125 ? -28.538 62.271  41.931 1.00 102.70 ? 133 GLU A CA  1 
ATOM   974   C C   . GLU A 1 125 ? -29.868 62.987  42.229 1.00 96.22  ? 133 GLU A C   1 
ATOM   975   O O   . GLU A 1 125 ? -30.295 63.116  43.388 1.00 66.44  ? 133 GLU A O   1 
ATOM   976   C CB  . GLU A 1 125 ? -28.791 60.867  41.378 1.00 101.59 ? 133 GLU A CB  1 
ATOM   977   C CG  . GLU A 1 125 ? -27.544 59.993  41.243 1.00 107.32 ? 133 GLU A CG  1 
ATOM   978   C CD  . GLU A 1 125 ? -27.977 58.575  40.874 1.00 122.56 ? 133 GLU A CD  1 
ATOM   979   O OE1 . GLU A 1 125 ? -28.952 58.157  41.568 1.00 119.75 ? 133 GLU A OE1 1 
ATOM   980   O OE2 . GLU A 1 125 ? -27.417 57.886  39.948 1.00 92.03  ? 133 GLU A OE2 1 
ATOM   981   N N   . PRO A 1 126 ? -30.524 63.533  41.181 1.00 83.01  ? 134 PRO A N   1 
ATOM   982   C CA  . PRO A 1 126 ? -31.500 64.612  41.346 1.00 92.10  ? 134 PRO A CA  1 
ATOM   983   C C   . PRO A 1 126 ? -32.660 64.232  42.249 1.00 94.35  ? 134 PRO A C   1 
ATOM   984   O O   . PRO A 1 126 ? -33.199 63.154  42.127 1.00 116.33 ? 134 PRO A O   1 
ATOM   985   C CB  . PRO A 1 126 ? -31.938 64.778  39.923 1.00 77.28  ? 134 PRO A CB  1 
ATOM   986   C CG  . PRO A 1 126 ? -30.654 64.588  39.189 1.00 83.02  ? 134 PRO A CG  1 
ATOM   987   C CD  . PRO A 1 126 ? -30.295 63.213  39.772 1.00 87.62  ? 134 PRO A CD  1 
ATOM   988   N N   . HIS A 1 127 ? -32.982 65.113  43.183 1.00 82.53  ? 135 HIS A N   1 
ATOM   989   C CA  . HIS A 1 127 ? -34.112 64.920  44.076 1.00 76.78  ? 135 HIS A CA  1 
ATOM   990   C C   . HIS A 1 127 ? -33.765 63.961  45.224 1.00 77.24  ? 135 HIS A C   1 
ATOM   991   O O   . HIS A 1 127 ? -34.598 63.692  46.118 1.00 68.89  ? 135 HIS A O   1 
ATOM   992   C CB  . HIS A 1 127 ? -35.404 64.779  43.256 1.00 78.77  ? 135 HIS A CB  1 
ATOM   993   C CG  . HIS A 1 127 ? -35.671 66.022  42.479 1.00 101.64 ? 135 HIS A CG  1 
ATOM   994   N ND1 . HIS A 1 127 ? -36.272 67.080  43.132 1.00 100.20 ? 135 HIS A ND1 1 
ATOM   995   C CD2 . HIS A 1 127 ? -35.441 66.458  41.213 1.00 92.36  ? 135 HIS A CD2 1 
ATOM   996   C CE1 . HIS A 1 127 ? -36.392 68.122  42.325 1.00 87.83  ? 135 HIS A CE1 1 
ATOM   997   N NE2 . HIS A 1 127 ? -35.878 67.773  41.158 1.00 96.63  ? 135 HIS A NE2 1 
ATOM   998   N N   . GLY A 1 128 ? -32.513 63.466  45.210 1.00 63.95  ? 136 GLY A N   1 
ATOM   999   C CA  . GLY A 1 128 ? -32.003 62.655  46.314 1.00 87.24  ? 136 GLY A CA  1 
ATOM   1000  C C   . GLY A 1 128 ? -31.975 63.469  47.602 1.00 88.44  ? 136 GLY A C   1 
ATOM   1001  O O   . GLY A 1 128 ? -31.895 64.714  47.583 1.00 81.14  ? 136 GLY A O   1 
ATOM   1002  N N   . ARG A 1 129 ? -32.111 62.753  48.726 1.00 74.29  ? 137 ARG A N   1 
ATOM   1003  C CA  . ARG A 1 129 ? -32.300 63.480  49.976 1.00 88.10  ? 137 ARG A CA  1 
ATOM   1004  C C   . ARG A 1 129 ? -30.958 63.800  50.635 1.00 92.42  ? 137 ARG A C   1 
ATOM   1005  O O   . ARG A 1 129 ? -30.124 62.914  50.834 1.00 77.58  ? 137 ARG A O   1 
ATOM   1006  C CB  . ARG A 1 129 ? -33.319 62.777  50.874 1.00 80.36  ? 137 ARG A CB  1 
ATOM   1007  C CG  . ARG A 1 129 ? -34.680 63.068  50.241 1.00 84.63  ? 137 ARG A CG  1 
ATOM   1008  C CD  . ARG A 1 129 ? -35.840 62.094  49.998 1.00 83.00  ? 137 ARG A CD  1 
ATOM   1009  N NE  . ARG A 1 129 ? -36.605 61.729  51.187 1.00 95.23  ? 137 ARG A NE  1 
ATOM   1010  C CZ  . ARG A 1 129 ? -37.907 61.876  51.345 1.00 88.78  ? 137 ARG A CZ  1 
ATOM   1011  N NH1 . ARG A 1 129 ? -38.418 61.292  52.426 1.00 63.14  ? 137 ARG A NH1 1 
ATOM   1012  N NH2 . ARG A 1 129 ? -38.663 62.497  50.431 1.00 67.17  ? 137 ARG A NH2 1 
ATOM   1013  N N   . ILE A 1 130 ? -30.792 65.064  51.040 1.00 95.64  ? 138 ILE A N   1 
ATOM   1014  C CA  . ILE A 1 130 ? -29.567 65.461  51.719 1.00 76.73  ? 138 ILE A CA  1 
ATOM   1015  C C   . ILE A 1 130 ? -29.935 66.082  53.066 1.00 82.66  ? 138 ILE A C   1 
ATOM   1016  O O   . ILE A 1 130 ? -30.955 66.755  53.162 1.00 98.00  ? 138 ILE A O   1 
ATOM   1017  C CB  . ILE A 1 130 ? -28.746 66.431  50.857 1.00 55.40  ? 138 ILE A CB  1 
ATOM   1018  C CG1 . ILE A 1 130 ? -28.436 65.870  49.477 1.00 44.64  ? 138 ILE A CG1 1 
ATOM   1019  C CG2 . ILE A 1 130 ? -27.489 66.782  51.630 1.00 46.96  ? 138 ILE A CG2 1 
ATOM   1020  C CD1 . ILE A 1 130 ? -27.724 66.882  48.569 1.00 55.61  ? 138 ILE A CD1 1 
ATOM   1021  N N   . MET A 1 131 ? -29.130 65.820  54.110 1.00 84.95  ? 139 MET A N   1 
ATOM   1022  C CA  . MET A 1 131 ? -29.289 66.497  55.391 1.00 84.41  ? 139 MET A CA  1 
ATOM   1023  C C   . MET A 1 131 ? -27.996 67.201  55.748 1.00 74.54  ? 139 MET A C   1 
ATOM   1024  O O   . MET A 1 131 ? -26.905 66.604  55.722 1.00 89.81  ? 139 MET A O   1 
ATOM   1025  C CB  . MET A 1 131 ? -29.680 65.555  56.539 1.00 73.77  ? 139 MET A CB  1 
ATOM   1026  C CG  . MET A 1 131 ? -31.130 65.062  56.455 1.00 72.90  ? 139 MET A CG  1 
ATOM   1027  S SD  . MET A 1 131 ? -31.467 63.857  57.759 1.00 72.71  ? 139 MET A SD  1 
ATOM   1028  C CE  . MET A 1 131 ? -31.790 65.001  59.108 1.00 64.16  ? 139 MET A CE  1 
ATOM   1029  N N   . GLY A 1 132 ? -28.173 68.474  56.105 1.00 71.00  ? 140 GLY A N   1 
ATOM   1030  C CA  . GLY A 1 132 ? -27.070 69.268  56.630 1.00 114.33 ? 140 GLY A CA  1 
ATOM   1031  C C   . GLY A 1 132 ? -27.528 70.115  57.810 1.00 120.03 ? 140 GLY A C   1 
ATOM   1032  O O   . GLY A 1 132 ? -28.741 70.235  58.059 1.00 128.69 ? 140 GLY A O   1 
ATOM   1033  N N   . LEU A 1 133 ? -26.560 70.732  58.505 1.00 86.75  ? 141 LEU A N   1 
ATOM   1034  C CA  . LEU A 1 133 ? -26.967 71.594  59.608 1.00 98.93  ? 141 LEU A CA  1 
ATOM   1035  C C   . LEU A 1 133 ? -27.836 72.758  59.106 1.00 88.72  ? 141 LEU A C   1 
ATOM   1036  O O   . LEU A 1 133 ? -27.440 73.394  58.165 1.00 78.92  ? 141 LEU A O   1 
ATOM   1037  C CB  . LEU A 1 133 ? -25.678 72.137  60.220 1.00 107.35 ? 141 LEU A CB  1 
ATOM   1038  C CG  . LEU A 1 133 ? -25.845 72.996  61.481 1.00 77.27  ? 141 LEU A CG  1 
ATOM   1039  C CD1 . LEU A 1 133 ? -26.613 72.270  62.564 1.00 60.57  ? 141 LEU A CD1 1 
ATOM   1040  C CD2 . LEU A 1 133 ? -24.467 73.353  61.987 1.00 71.25  ? 141 LEU A CD2 1 
ATOM   1041  N N   . ASP A 1 134 ? -28.970 73.088  59.746 1.00 95.65  ? 142 ASP A N   1 
ATOM   1042  C CA  . ASP A 1 134 ? -29.781 74.234  59.336 1.00 77.80  ? 142 ASP A CA  1 
ATOM   1043  C C   . ASP A 1 134 ? -28.880 75.463  59.260 1.00 74.90  ? 142 ASP A C   1 
ATOM   1044  O O   . ASP A 1 134 ? -28.009 75.647  60.092 1.00 103.95 ? 142 ASP A O   1 
ATOM   1045  C CB  . ASP A 1 134 ? -30.914 74.583  60.302 1.00 74.65  ? 142 ASP A CB  1 
ATOM   1046  C CG  . ASP A 1 134 ? -32.094 75.304  59.634 1.00 81.47  ? 142 ASP A CG  1 
ATOM   1047  O OD1 . ASP A 1 134 ? -31.953 75.690  58.482 1.00 88.22  ? 142 ASP A OD1 1 
ATOM   1048  O OD2 . ASP A 1 134 ? -33.241 75.351  60.185 1.00 65.86  ? 142 ASP A OD2 1 
ATOM   1049  N N   . LEU A 1 135 ? -29.088 76.295  58.242 1.00 65.36  ? 143 LEU A N   1 
ATOM   1050  C CA  . LEU A 1 135 ? -28.235 77.453  58.016 1.00 53.24  ? 143 LEU A CA  1 
ATOM   1051  C C   . LEU A 1 135 ? -28.164 78.388  59.236 1.00 59.83  ? 143 LEU A C   1 
ATOM   1052  O O   . LEU A 1 135 ? -27.071 78.684  59.722 1.00 50.00  ? 143 LEU A O   1 
ATOM   1053  C CB  . LEU A 1 135 ? -28.803 78.138  56.777 1.00 45.44  ? 143 LEU A CB  1 
ATOM   1054  C CG  . LEU A 1 135 ? -27.867 79.196  56.208 1.00 55.64  ? 143 LEU A CG  1 
ATOM   1055  C CD1 . LEU A 1 135 ? -26.441 78.718  56.036 1.00 44.23  ? 143 LEU A CD1 1 
ATOM   1056  C CD2 . LEU A 1 135 ? -28.416 79.449  54.834 1.00 66.34  ? 143 LEU A CD2 1 
ATOM   1057  N N   . PRO A 1 136 ? -29.287 78.888  59.802 1.00 66.96  ? 144 PRO A N   1 
ATOM   1058  C CA  . PRO A 1 136 ? -29.202 79.785  60.966 1.00 80.24  ? 144 PRO A CA  1 
ATOM   1059  C C   . PRO A 1 136 ? -28.555 79.115  62.187 1.00 80.71  ? 144 PRO A C   1 
ATOM   1060  O O   . PRO A 1 136 ? -28.140 79.807  63.112 1.00 76.48  ? 144 PRO A O   1 
ATOM   1061  C CB  . PRO A 1 136 ? -30.640 80.208  61.266 1.00 80.55  ? 144 PRO A CB  1 
ATOM   1062  C CG  . PRO A 1 136 ? -31.427 79.086  60.639 1.00 98.62  ? 144 PRO A CG  1 
ATOM   1063  C CD  . PRO A 1 136 ? -30.677 78.543  59.438 1.00 81.61  ? 144 PRO A CD  1 
ATOM   1064  N N   . ASP A 1 137 ? -28.430 77.786  62.164 1.00 69.68  ? 145 ASP A N   1 
ATOM   1065  C CA  . ASP A 1 137 ? -27.757 77.073  63.233 1.00 69.32  ? 145 ASP A CA  1 
ATOM   1066  C C   . ASP A 1 137 ? -26.270 76.850  62.894 1.00 80.49  ? 145 ASP A C   1 
ATOM   1067  O O   . ASP A 1 137 ? -25.603 76.104  63.605 1.00 88.17  ? 145 ASP A O   1 
ATOM   1068  C CB  . ASP A 1 137 ? -28.384 75.696  63.411 1.00 86.46  ? 145 ASP A CB  1 
ATOM   1069  C CG  . ASP A 1 137 ? -29.827 75.638  63.859 1.00 106.88 ? 145 ASP A CG  1 
ATOM   1070  O OD1 . ASP A 1 137 ? -30.489 76.707  63.778 1.00 102.31 ? 145 ASP A OD1 1 
ATOM   1071  O OD2 . ASP A 1 137 ? -30.247 74.524  64.277 1.00 91.08  ? 145 ASP A OD2 1 
ATOM   1072  N N   . GLY A 1 138 ? -25.743 77.451  61.811 1.00 71.52  ? 146 GLY A N   1 
ATOM   1073  C CA  . GLY A 1 138 ? -24.320 77.372  61.504 1.00 88.89  ? 146 GLY A CA  1 
ATOM   1074  C C   . GLY A 1 138 ? -23.995 76.488  60.290 1.00 104.73 ? 146 GLY A C   1 
ATOM   1075  O O   . GLY A 1 138 ? -22.820 76.177  60.049 1.00 85.78  ? 146 GLY A O   1 
ATOM   1076  N N   . GLY A 1 139 ? -25.031 76.117  59.521 1.00 93.23  ? 147 GLY A N   1 
ATOM   1077  C CA  . GLY A 1 139 ? -24.854 75.420  58.259 1.00 71.68  ? 147 GLY A CA  1 
ATOM   1078  C C   . GLY A 1 139 ? -24.321 76.363  57.170 1.00 84.02  ? 147 GLY A C   1 
ATOM   1079  O O   . GLY A 1 139 ? -24.103 77.539  57.434 1.00 96.26  ? 147 GLY A O   1 
ATOM   1080  N N   . HIS A 1 140 ? -24.079 75.859  55.944 1.00 91.02  ? 148 HIS A N   1 
ATOM   1081  C CA  . HIS A 1 140 ? -23.802 76.698  54.777 1.00 100.94 ? 148 HIS A CA  1 
ATOM   1082  C C   . HIS A 1 140 ? -24.902 76.498  53.736 1.00 104.54 ? 148 HIS A C   1 
ATOM   1083  O O   . HIS A 1 140 ? -25.426 75.381  53.655 1.00 76.44  ? 148 HIS A O   1 
ATOM   1084  C CB  . HIS A 1 140 ? -22.452 76.418  54.101 1.00 91.10  ? 148 HIS A CB  1 
ATOM   1085  C CG  . HIS A 1 140 ? -22.183 77.407  52.995 1.00 84.95  ? 148 HIS A CG  1 
ATOM   1086  N ND1 . HIS A 1 140 ? -21.265 77.264  51.977 1.00 70.44  ? 148 HIS A ND1 1 
ATOM   1087  C CD2 . HIS A 1 140 ? -22.843 78.584  52.730 1.00 98.16  ? 148 HIS A CD2 1 
ATOM   1088  C CE1 . HIS A 1 140 ? -21.325 78.326  51.170 1.00 91.45  ? 148 HIS A CE1 1 
ATOM   1089  N NE2 . HIS A 1 140 ? -22.291 79.129  51.593 1.00 116.43 ? 148 HIS A NE2 1 
ATOM   1090  N N   . LEU A 1 141 ? -25.218 77.546  52.925 1.00 93.89  ? 149 LEU A N   1 
ATOM   1091  C CA  . LEU A 1 141 ? -26.233 77.432  51.874 1.00 94.74  ? 149 LEU A CA  1 
ATOM   1092  C C   . LEU A 1 141 ? -26.063 76.140  51.085 1.00 107.45 ? 149 LEU A C   1 
ATOM   1093  O O   . LEU A 1 141 ? -27.048 75.436  50.887 1.00 144.84 ? 149 LEU A O   1 
ATOM   1094  C CB  . LEU A 1 141 ? -26.352 78.580  50.878 1.00 76.07  ? 149 LEU A CB  1 
ATOM   1095  C CG  . LEU A 1 141 ? -27.252 79.752  51.262 1.00 57.73  ? 149 LEU A CG  1 
ATOM   1096  C CD1 . LEU A 1 141 ? -26.672 80.010  52.616 1.00 68.50  ? 149 LEU A CD1 1 
ATOM   1097  C CD2 . LEU A 1 141 ? -26.984 80.931  50.253 1.00 32.77  ? 149 LEU A CD2 1 
ATOM   1098  N N   . THR A 1 142 ? -24.839 75.865  50.611 1.00 81.37  ? 150 THR A N   1 
ATOM   1099  C CA  . THR A 1 142 ? -24.574 74.675  49.811 1.00 77.95  ? 150 THR A CA  1 
ATOM   1100  C C   . THR A 1 142 ? -24.916 73.357  50.534 1.00 85.03  ? 150 THR A C   1 
ATOM   1101  O O   . THR A 1 142 ? -24.885 72.306  49.890 1.00 83.64  ? 150 THR A O   1 
ATOM   1102  C CB  . THR A 1 142 ? -23.125 74.659  49.336 1.00 76.00  ? 150 THR A CB  1 
ATOM   1103  O OG1 . THR A 1 142 ? -22.349 74.436  50.503 1.00 70.50  ? 150 THR A OG1 1 
ATOM   1104  C CG2 . THR A 1 142 ? -22.672 75.974  48.727 1.00 80.92  ? 150 THR A CG2 1 
ATOM   1105  N N   . HIS A 1 143 ? -25.242 73.395  51.844 1.00 62.35  ? 151 HIS A N   1 
ATOM   1106  C CA  . HIS A 1 143 ? -25.618 72.211  52.588 1.00 58.43  ? 151 HIS A CA  1 
ATOM   1107  C C   . HIS A 1 143 ? -27.143 72.116  52.637 1.00 60.62  ? 151 HIS A C   1 
ATOM   1108  O O   . HIS A 1 143 ? -27.741 71.485  53.515 1.00 67.26  ? 151 HIS A O   1 
ATOM   1109  C CB  . HIS A 1 143 ? -25.077 72.313  54.020 1.00 77.93  ? 151 HIS A CB  1 
ATOM   1110  C CG  . HIS A 1 143 ? -23.613 72.445  54.155 1.00 79.19  ? 151 HIS A CG  1 
ATOM   1111  N ND1 . HIS A 1 143 ? -22.997 72.547  55.378 1.00 76.71  ? 151 HIS A ND1 1 
ATOM   1112  C CD2 . HIS A 1 143 ? -22.642 72.408  53.245 1.00 81.56  ? 151 HIS A CD2 1 
ATOM   1113  C CE1 . HIS A 1 143 ? -21.670 72.610  55.174 1.00 82.87  ? 151 HIS A CE1 1 
ATOM   1114  N NE2 . HIS A 1 143 ? -21.431 72.559  53.884 1.00 70.67  ? 151 HIS A NE2 1 
ATOM   1115  N N   . GLY A 1 144 ? -27.797 72.894  51.790 1.00 62.05  ? 152 GLY A N   1 
ATOM   1116  C CA  . GLY A 1 144 ? -29.250 72.893  51.708 1.00 70.07  ? 152 GLY A CA  1 
ATOM   1117  C C   . GLY A 1 144 ? -29.847 74.102  52.437 1.00 88.27  ? 152 GLY A C   1 
ATOM   1118  O O   . GLY A 1 144 ? -29.403 74.455  53.516 1.00 114.15 ? 152 GLY A O   1 
ATOM   1119  N N   . PHE A 1 145 ? -30.881 74.724  51.866 1.00 89.07  ? 153 PHE A N   1 
ATOM   1120  C CA  . PHE A 1 145 ? -31.602 75.787  52.544 1.00 68.76  ? 153 PHE A CA  1 
ATOM   1121  C C   . PHE A 1 145 ? -32.841 76.124  51.730 1.00 74.72  ? 153 PHE A C   1 
ATOM   1122  O O   . PHE A 1 145 ? -32.763 76.535  50.529 1.00 69.79  ? 153 PHE A O   1 
ATOM   1123  C CB  . PHE A 1 145 ? -30.704 77.021  52.655 1.00 88.24  ? 153 PHE A CB  1 
ATOM   1124  C CG  . PHE A 1 145 ? -31.433 78.246  53.191 1.00 93.74  ? 153 PHE A CG  1 
ATOM   1125  C CD1 . PHE A 1 145 ? -32.323 78.122  54.252 1.00 94.90  ? 153 PHE A CD1 1 
ATOM   1126  C CD2 . PHE A 1 145 ? -31.315 79.492  52.577 1.00 87.62  ? 153 PHE A CD2 1 
ATOM   1127  C CE1 . PHE A 1 145 ? -33.015 79.226  54.736 1.00 85.66  ? 153 PHE A CE1 1 
ATOM   1128  C CE2 . PHE A 1 145 ? -31.997 80.597  53.089 1.00 74.08  ? 153 PHE A CE2 1 
ATOM   1129  C CZ  . PHE A 1 145 ? -32.834 80.464  54.168 1.00 69.56  ? 153 PHE A CZ  1 
ATOM   1130  N N   . MET A 1 146 ? -33.979 75.927  52.407 1.00 64.50  ? 154 MET A N   1 
ATOM   1131  C CA  . MET A 1 146 ? -35.248 76.157  51.719 1.00 66.19  ? 154 MET A CA  1 
ATOM   1132  C C   . MET A 1 146 ? -36.321 76.519  52.727 1.00 59.02  ? 154 MET A C   1 
ATOM   1133  O O   . MET A 1 146 ? -36.327 76.016  53.838 1.00 58.57  ? 154 MET A O   1 
ATOM   1134  C CB  . MET A 1 146 ? -35.741 75.002  50.837 1.00 65.06  ? 154 MET A CB  1 
ATOM   1135  C CG  . MET A 1 146 ? -35.945 73.703  51.587 1.00 70.25  ? 154 MET A CG  1 
ATOM   1136  S SD  . MET A 1 146 ? -36.328 72.329  50.468 1.00 107.67 ? 154 MET A SD  1 
ATOM   1137  C CE  . MET A 1 146 ? -38.043 72.374  51.026 1.00 89.44  ? 154 MET A CE  1 
ATOM   1138  N N   . THR A 1 147 ? -37.165 77.467  52.321 1.00 47.38  ? 155 THR A N   1 
ATOM   1139  C CA  . THR A 1 147 ? -38.134 78.160  53.157 1.00 48.86  ? 155 THR A CA  1 
ATOM   1140  C C   . THR A 1 147 ? -39.513 77.684  52.706 1.00 57.71  ? 155 THR A C   1 
ATOM   1141  O O   . THR A 1 147 ? -39.613 77.071  51.632 1.00 42.87  ? 155 THR A O   1 
ATOM   1142  C CB  . THR A 1 147 ? -37.926 79.658  52.901 1.00 45.99  ? 155 THR A CB  1 
ATOM   1143  O OG1 . THR A 1 147 ? -38.732 80.258  51.859 1.00 36.37  ? 155 THR A OG1 1 
ATOM   1144  C CG2 . THR A 1 147 ? -36.442 79.986  52.760 1.00 38.13  ? 155 THR A CG2 1 
ATOM   1145  N N   . ASP A 1 148 ? -40.553 77.946  53.527 1.00 66.97  ? 156 ASP A N   1 
ATOM   1146  C CA  . ASP A 1 148 ? -41.908 77.515  53.199 1.00 83.60  ? 156 ASP A CA  1 
ATOM   1147  C C   . ASP A 1 148 ? -42.310 78.046  51.802 1.00 95.47  ? 156 ASP A C   1 
ATOM   1148  O O   . ASP A 1 148 ? -43.136 77.403  51.101 1.00 68.40  ? 156 ASP A O   1 
ATOM   1149  C CB  . ASP A 1 148 ? -42.849 77.820  54.360 1.00 86.60  ? 156 ASP A CB  1 
ATOM   1150  C CG  . ASP A 1 148 ? -43.177 79.311  54.490 1.00 115.33 ? 156 ASP A CG  1 
ATOM   1151  O OD1 . ASP A 1 148 ? -42.263 80.161  54.238 1.00 94.62  ? 156 ASP A OD1 1 
ATOM   1152  O OD2 . ASP A 1 148 ? -44.342 79.646  54.840 1.00 111.95 ? 156 ASP A OD2 1 
ATOM   1153  N N   . LYS A 1 149 ? -41.694 79.181  51.384 1.00 87.60  ? 157 LYS A N   1 
ATOM   1154  C CA  . LYS A 1 149 ? -41.968 79.803  50.090 1.00 86.33  ? 157 LYS A CA  1 
ATOM   1155  C C   . LYS A 1 149 ? -41.031 79.120  49.091 1.00 84.63  ? 157 LYS A C   1 
ATOM   1156  O O   . LYS A 1 149 ? -41.448 78.306  48.279 1.00 109.87 ? 157 LYS A O   1 
ATOM   1157  C CB  . LYS A 1 149 ? -41.589 81.290  50.006 1.00 78.07  ? 157 LYS A CB  1 
ATOM   1158  C CG  . LYS A 1 149 ? -41.998 82.297  51.088 1.00 97.93  ? 157 LYS A CG  1 
ATOM   1159  C CD  . LYS A 1 149 ? -43.488 82.596  51.258 1.00 82.10  ? 157 LYS A CD  1 
ATOM   1160  C CE  . LYS A 1 149 ? -43.780 83.144  52.643 1.00 104.86 ? 157 LYS A CE  1 
ATOM   1161  N NZ  . LYS A 1 149 ? -45.172 83.074  53.129 1.00 153.37 ? 157 LYS A NZ  1 
ATOM   1162  N N   . LYS A 1 150 ? -39.726 79.333  49.268 1.00 67.09  ? 158 LYS A N   1 
ATOM   1163  C CA  . LYS A 1 150 ? -38.826 79.214  48.128 1.00 63.46  ? 158 LYS A CA  1 
ATOM   1164  C C   . LYS A 1 150 ? -37.605 78.341  48.445 1.00 75.73  ? 158 LYS A C   1 
ATOM   1165  O O   . LYS A 1 150 ? -36.992 78.496  49.522 1.00 55.78  ? 158 LYS A O   1 
ATOM   1166  C CB  . LYS A 1 150 ? -38.418 80.654  47.788 1.00 50.52  ? 158 LYS A CB  1 
ATOM   1167  C CG  . LYS A 1 150 ? -37.598 80.683  46.484 1.00 71.32  ? 158 LYS A CG  1 
ATOM   1168  C CD  . LYS A 1 150 ? -36.916 81.977  46.008 1.00 79.76  ? 158 LYS A CD  1 
ATOM   1169  C CE  . LYS A 1 150 ? -37.292 83.429  46.263 1.00 80.55  ? 158 LYS A CE  1 
ATOM   1170  N NZ  . LYS A 1 150 ? -36.791 84.247  45.138 1.00 91.84  ? 158 LYS A NZ  1 
ATOM   1171  N N   . LYS A 1 151 ? -37.246 77.466  47.472 1.00 82.99  ? 159 LYS A N   1 
ATOM   1172  C CA  . LYS A 1 151 ? -35.987 76.742  47.560 1.00 74.59  ? 159 LYS A CA  1 
ATOM   1173  C C   . LYS A 1 151 ? -34.902 77.721  47.131 1.00 76.19  ? 159 LYS A C   1 
ATOM   1174  O O   . LYS A 1 151 ? -34.947 78.187  46.000 1.00 82.29  ? 159 LYS A O   1 
ATOM   1175  C CB  . LYS A 1 151 ? -35.973 75.517  46.646 1.00 61.92  ? 159 LYS A CB  1 
ATOM   1176  C CG  . LYS A 1 151 ? -36.942 74.445  47.225 1.00 66.69  ? 159 LYS A CG  1 
ATOM   1177  C CD  . LYS A 1 151 ? -37.027 73.160  46.405 1.00 77.40  ? 159 LYS A CD  1 
ATOM   1178  C CE  . LYS A 1 151 ? -38.462 72.741  45.999 1.00 59.76  ? 159 LYS A CE  1 
ATOM   1179  N NZ  . LYS A 1 151 ? -38.541 71.299  45.722 1.00 60.02  ? 159 LYS A NZ  1 
ATOM   1180  N N   . ILE A 1 152 ? -34.012 78.103  48.064 1.00 55.63  ? 160 ILE A N   1 
ATOM   1181  C CA  . ILE A 1 152 ? -33.093 79.201  47.827 1.00 57.00  ? 160 ILE A CA  1 
ATOM   1182  C C   . ILE A 1 152 ? -31.799 78.638  47.252 1.00 80.16  ? 160 ILE A C   1 
ATOM   1183  O O   . ILE A 1 152 ? -31.303 79.117  46.233 1.00 71.54  ? 160 ILE A O   1 
ATOM   1184  C CB  . ILE A 1 152 ? -32.772 79.904  49.156 1.00 71.27  ? 160 ILE A CB  1 
ATOM   1185  C CG1 . ILE A 1 152 ? -33.993 80.677  49.639 1.00 50.74  ? 160 ILE A CG1 1 
ATOM   1186  C CG2 . ILE A 1 152 ? -31.509 80.804  49.061 1.00 57.45  ? 160 ILE A CG2 1 
ATOM   1187  C CD1 . ILE A 1 152 ? -34.514 81.507  48.490 1.00 47.89  ? 160 ILE A CD1 1 
ATOM   1188  N N   . SER A 1 153 ? -31.182 77.720  48.019 1.00 82.29  ? 161 SER A N   1 
ATOM   1189  C CA  . SER A 1 153 ? -29.897 77.172  47.640 1.00 73.02  ? 161 SER A CA  1 
ATOM   1190  C C   . SER A 1 153 ? -30.105 76.221  46.469 1.00 70.14  ? 161 SER A C   1 
ATOM   1191  O O   . SER A 1 153 ? -31.078 75.463  46.476 1.00 78.53  ? 161 SER A O   1 
ATOM   1192  C CB  . SER A 1 153 ? -29.319 76.427  48.774 1.00 90.13  ? 161 SER A CB  1 
ATOM   1193  O OG  . SER A 1 153 ? -28.187 75.714  48.295 1.00 108.96 ? 161 SER A OG  1 
ATOM   1194  N N   . ALA A 1 154 ? -29.170 76.232  45.513 1.00 63.26  ? 162 ALA A N   1 
ATOM   1195  C CA  . ALA A 1 154 ? -29.225 75.299  44.403 1.00 69.13  ? 162 ALA A CA  1 
ATOM   1196  C C   . ALA A 1 154 ? -29.246 73.852  44.901 1.00 73.63  ? 162 ALA A C   1 
ATOM   1197  O O   . ALA A 1 154 ? -29.933 73.005  44.308 1.00 65.25  ? 162 ALA A O   1 
ATOM   1198  C CB  . ALA A 1 154 ? -28.079 75.542  43.468 1.00 66.42  ? 162 ALA A CB  1 
ATOM   1199  N N   . THR A 1 155 ? -28.552 73.591  46.023 1.00 59.28  ? 163 THR A N   1 
ATOM   1200  C CA  . THR A 1 155 ? -28.605 72.276  46.663 1.00 56.84  ? 163 THR A CA  1 
ATOM   1201  C C   . THR A 1 155 ? -30.063 71.909  46.903 1.00 53.94  ? 163 THR A C   1 
ATOM   1202  O O   . THR A 1 155 ? -30.514 70.817  46.553 1.00 56.30  ? 163 THR A O   1 
ATOM   1203  C CB  . THR A 1 155 ? -27.842 72.247  47.981 1.00 54.74  ? 163 THR A CB  1 
ATOM   1204  O OG1 . THR A 1 155 ? -26.523 72.707  47.713 1.00 86.37  ? 163 THR A OG1 1 
ATOM   1205  C CG2 . THR A 1 155 ? -27.678 70.827  48.478 1.00 63.17  ? 163 THR A CG2 1 
ATOM   1206  N N   . SER A 1 156 ? -30.817 72.882  47.410 1.00 49.50  ? 164 SER A N   1 
ATOM   1207  C CA  . SER A 1 156 ? -32.195 72.628  47.788 1.00 64.21  ? 164 SER A CA  1 
ATOM   1208  C C   . SER A 1 156 ? -33.169 72.670  46.598 1.00 79.03  ? 164 SER A C   1 
ATOM   1209  O O   . SER A 1 156 ? -34.296 72.164  46.715 1.00 100.14 ? 164 SER A O   1 
ATOM   1210  C CB  . SER A 1 156 ? -32.584 73.607  48.821 1.00 59.05  ? 164 SER A CB  1 
ATOM   1211  O OG  . SER A 1 156 ? -32.233 73.163  50.114 1.00 39.54  ? 164 SER A OG  1 
ATOM   1212  N N   . ILE A 1 157 ? -32.721 73.252  45.472 1.00 54.89  ? 165 ILE A N   1 
ATOM   1213  C CA  . ILE A 1 157 ? -33.507 73.269  44.252 1.00 68.88  ? 165 ILE A CA  1 
ATOM   1214  C C   . ILE A 1 157 ? -33.423 71.919  43.546 1.00 82.52  ? 165 ILE A C   1 
ATOM   1215  O O   . ILE A 1 157 ? -34.464 71.415  43.119 1.00 82.64  ? 165 ILE A O   1 
ATOM   1216  C CB  . ILE A 1 157 ? -32.952 74.346  43.303 1.00 72.60  ? 165 ILE A CB  1 
ATOM   1217  C CG1 . ILE A 1 157 ? -33.078 75.731  43.960 1.00 59.63  ? 165 ILE A CG1 1 
ATOM   1218  C CG2 . ILE A 1 157 ? -33.554 74.251  41.883 1.00 51.09  ? 165 ILE A CG2 1 
ATOM   1219  C CD1 . ILE A 1 157 ? -32.374 76.774  43.131 1.00 43.45  ? 165 ILE A CD1 1 
ATOM   1220  N N   . PHE A 1 158 ? -32.192 71.393  43.384 1.00 75.74  ? 166 PHE A N   1 
ATOM   1221  C CA  . PHE A 1 158 ? -32.005 70.239  42.525 1.00 88.48  ? 166 PHE A CA  1 
ATOM   1222  C C   . PHE A 1 158 ? -31.982 68.928  43.303 1.00 89.55  ? 166 PHE A C   1 
ATOM   1223  O O   . PHE A 1 158 ? -32.099 67.882  42.669 1.00 88.33  ? 166 PHE A O   1 
ATOM   1224  C CB  . PHE A 1 158 ? -30.678 70.373  41.790 1.00 85.77  ? 166 PHE A CB  1 
ATOM   1225  C CG  . PHE A 1 158 ? -30.635 71.525  40.813 1.00 64.96  ? 166 PHE A CG  1 
ATOM   1226  C CD1 . PHE A 1 158 ? -31.283 71.413  39.582 1.00 55.02  ? 166 PHE A CD1 1 
ATOM   1227  C CD2 . PHE A 1 158 ? -29.913 72.677  41.107 1.00 60.68  ? 166 PHE A CD2 1 
ATOM   1228  C CE1 . PHE A 1 158 ? -31.216 72.452  38.649 1.00 56.06  ? 166 PHE A CE1 1 
ATOM   1229  C CE2 . PHE A 1 158 ? -29.871 73.731  40.194 1.00 77.04  ? 166 PHE A CE2 1 
ATOM   1230  C CZ  . PHE A 1 158 ? -30.508 73.610  38.947 1.00 70.77  ? 166 PHE A CZ  1 
ATOM   1231  N N   . PHE A 1 159 ? -31.844 69.007  44.638 1.00 78.76  ? 167 PHE A N   1 
ATOM   1232  C CA  . PHE A 1 159 ? -31.964 67.871  45.554 1.00 81.59  ? 167 PHE A CA  1 
ATOM   1233  C C   . PHE A 1 159 ? -32.998 68.206  46.625 1.00 78.99  ? 167 PHE A C   1 
ATOM   1234  O O   . PHE A 1 159 ? -33.302 69.379  46.857 1.00 102.34 ? 167 PHE A O   1 
ATOM   1235  C CB  . PHE A 1 159 ? -30.600 67.543  46.184 1.00 81.35  ? 167 PHE A CB  1 
ATOM   1236  C CG  . PHE A 1 159 ? -29.466 67.487  45.159 1.00 71.00  ? 167 PHE A CG  1 
ATOM   1237  C CD1 . PHE A 1 159 ? -29.229 66.328  44.416 1.00 64.96  ? 167 PHE A CD1 1 
ATOM   1238  C CD2 . PHE A 1 159 ? -28.654 68.597  44.915 1.00 65.17  ? 167 PHE A CD2 1 
ATOM   1239  C CE1 . PHE A 1 159 ? -28.203 66.276  43.486 1.00 73.47  ? 167 PHE A CE1 1 
ATOM   1240  C CE2 . PHE A 1 159 ? -27.668 68.559  43.925 1.00 61.41  ? 167 PHE A CE2 1 
ATOM   1241  C CZ  . PHE A 1 159 ? -27.425 67.402  43.228 1.00 59.89  ? 167 PHE A CZ  1 
ATOM   1242  N N   . GLU A 1 160 ? -33.519 67.180  47.311 1.00 66.52  ? 168 GLU A N   1 
ATOM   1243  C CA  . GLU A 1 160 ? -34.448 67.436  48.413 1.00 69.01  ? 168 GLU A CA  1 
ATOM   1244  C C   . GLU A 1 160 ? -33.687 67.470  49.747 1.00 92.20  ? 168 GLU A C   1 
ATOM   1245  O O   . GLU A 1 160 ? -33.168 66.424  50.234 1.00 86.59  ? 168 GLU A O   1 
ATOM   1246  C CB  . GLU A 1 160 ? -35.597 66.436  48.393 1.00 46.51  ? 168 GLU A CB  1 
ATOM   1247  C CG  . GLU A 1 160 ? -36.432 66.491  47.115 1.00 65.10  ? 168 GLU A CG  1 
ATOM   1248  C CD  . GLU A 1 160 ? -37.060 67.754  46.494 1.00 82.76  ? 168 GLU A CD  1 
ATOM   1249  O OE1 . GLU A 1 160 ? -38.123 68.225  47.098 1.00 59.81  ? 168 GLU A OE1 1 
ATOM   1250  O OE2 . GLU A 1 160 ? -36.484 68.222  45.393 1.00 45.46  ? 168 GLU A OE2 1 
ATOM   1251  N N   . SER A 1 161 ? -33.630 68.683  50.354 1.00 72.73  ? 169 SER A N   1 
ATOM   1252  C CA  . SER A 1 161 ? -32.805 68.748  51.555 1.00 71.73  ? 169 SER A CA  1 
ATOM   1253  C C   . SER A 1 161 ? -33.693 68.962  52.760 1.00 73.17  ? 169 SER A C   1 
ATOM   1254  O O   . SER A 1 161 ? -34.728 69.582  52.604 1.00 104.24 ? 169 SER A O   1 
ATOM   1255  C CB  . SER A 1 161 ? -31.751 69.828  51.538 1.00 77.63  ? 169 SER A CB  1 
ATOM   1256  O OG  . SER A 1 161 ? -32.371 71.078  51.816 1.00 84.78  ? 169 SER A OG  1 
ATOM   1257  N N   . MET A 1 162 ? -33.263 68.470  53.918 1.00 89.64  ? 170 MET A N   1 
ATOM   1258  C CA  . MET A 1 162 ? -33.881 68.796  55.188 1.00 98.97  ? 170 MET A CA  1 
ATOM   1259  C C   . MET A 1 162 ? -32.779 68.980  56.218 1.00 103.76 ? 170 MET A C   1 
ATOM   1260  O O   . MET A 1 162 ? -31.895 68.116  56.333 1.00 98.65  ? 170 MET A O   1 
ATOM   1261  C CB  . MET A 1 162 ? -34.761 67.647  55.693 1.00 97.86  ? 170 MET A CB  1 
ATOM   1262  C CG  . MET A 1 162 ? -35.550 68.072  56.921 1.00 105.31 ? 170 MET A CG  1 
ATOM   1263  S SD  . MET A 1 162 ? -36.902 66.935  57.289 1.00 105.07 ? 170 MET A SD  1 
ATOM   1264  C CE  . MET A 1 162 ? -35.865 65.689  58.067 1.00 114.55 ? 170 MET A CE  1 
ATOM   1265  N N   . PRO A 1 163 ? -32.779 70.106  56.973 1.00 99.57  ? 171 PRO A N   1 
ATOM   1266  C CA  . PRO A 1 163 ? -31.751 70.328  58.007 1.00 108.21 ? 171 PRO A CA  1 
ATOM   1267  C C   . PRO A 1 163 ? -31.870 69.645  59.370 1.00 119.73 ? 171 PRO A C   1 
ATOM   1268  O O   . PRO A 1 163 ? -32.974 69.330  59.810 1.00 126.30 ? 171 PRO A O   1 
ATOM   1269  C CB  . PRO A 1 163 ? -31.688 71.841  58.155 1.00 80.89  ? 171 PRO A CB  1 
ATOM   1270  C CG  . PRO A 1 163 ? -33.118 72.234  57.842 1.00 81.18  ? 171 PRO A CG  1 
ATOM   1271  C CD  . PRO A 1 163 ? -33.709 71.239  56.824 1.00 69.46  ? 171 PRO A CD  1 
ATOM   1272  N N   . TYR A 1 164 ? -30.700 69.399  59.999 1.00 118.49 ? 172 TYR A N   1 
ATOM   1273  C CA  . TYR A 1 164 ? -30.590 68.880  61.359 1.00 97.76  ? 172 TYR A CA  1 
ATOM   1274  C C   . TYR A 1 164 ? -30.141 70.053  62.229 1.00 92.27  ? 172 TYR A C   1 
ATOM   1275  O O   . TYR A 1 164 ? -29.516 70.974  61.684 1.00 52.61  ? 172 TYR A O   1 
ATOM   1276  C CB  . TYR A 1 164 ? -29.657 67.667  61.524 1.00 78.73  ? 172 TYR A CB  1 
ATOM   1277  C CG  . TYR A 1 164 ? -28.190 67.746  61.074 1.00 65.89  ? 172 TYR A CG  1 
ATOM   1278  C CD1 . TYR A 1 164 ? -27.232 68.327  61.879 1.00 62.17  ? 172 TYR A CD1 1 
ATOM   1279  C CD2 . TYR A 1 164 ? -27.729 67.221  59.871 1.00 73.66  ? 172 TYR A CD2 1 
ATOM   1280  C CE1 . TYR A 1 164 ? -25.890 68.391  61.556 1.00 47.04  ? 172 TYR A CE1 1 
ATOM   1281  C CE2 . TYR A 1 164 ? -26.388 67.301  59.505 1.00 66.95  ? 172 TYR A CE2 1 
ATOM   1282  C CZ  . TYR A 1 164 ? -25.459 67.871  60.364 1.00 67.68  ? 172 TYR A CZ  1 
ATOM   1283  O OH  . TYR A 1 164 ? -24.105 68.074  60.186 1.00 99.23  ? 172 TYR A OH  1 
ATOM   1284  N N   . LYS A 1 165 ? -30.494 70.041  63.538 1.00 92.35  ? 173 LYS A N   1 
ATOM   1285  C CA  . LYS A 1 165 ? -30.437 71.317  64.238 1.00 84.19  ? 173 LYS A CA  1 
ATOM   1286  C C   . LYS A 1 165 ? -29.401 71.295  65.344 1.00 93.87  ? 173 LYS A C   1 
ATOM   1287  O O   . LYS A 1 165 ? -28.903 70.225  65.697 1.00 88.14  ? 173 LYS A O   1 
ATOM   1288  C CB  . LYS A 1 165 ? -31.786 71.903  64.648 1.00 77.00  ? 173 LYS A CB  1 
ATOM   1289  C CG  . LYS A 1 165 ? -32.546 72.278  63.352 1.00 92.76  ? 173 LYS A CG  1 
ATOM   1290  C CD  . LYS A 1 165 ? -33.952 72.835  63.455 1.00 80.71  ? 173 LYS A CD  1 
ATOM   1291  C CE  . LYS A 1 165 ? -33.907 74.251  63.907 1.00 91.03  ? 173 LYS A CE  1 
ATOM   1292  N NZ  . LYS A 1 165 ? -33.202 75.047  62.900 1.00 71.92  ? 173 LYS A NZ  1 
ATOM   1293  N N   . VAL A 1 166 ? -29.062 72.517  65.792 1.00 80.46  ? 174 VAL A N   1 
ATOM   1294  C CA  . VAL A 1 166 ? -28.234 72.760  66.969 1.00 77.15  ? 174 VAL A CA  1 
ATOM   1295  C C   . VAL A 1 166 ? -29.191 72.974  68.140 1.00 80.20  ? 174 VAL A C   1 
ATOM   1296  O O   . VAL A 1 166 ? -30.166 73.710  68.027 1.00 90.59  ? 174 VAL A O   1 
ATOM   1297  C CB  . VAL A 1 166 ? -27.492 74.077  66.683 1.00 67.73  ? 174 VAL A CB  1 
ATOM   1298  C CG1 . VAL A 1 166 ? -26.649 74.539  67.876 1.00 71.57  ? 174 VAL A CG1 1 
ATOM   1299  C CG2 . VAL A 1 166 ? -26.639 73.956  65.442 1.00 64.43  ? 174 VAL A CG2 1 
ATOM   1300  N N   . ASN A 1 167 ? -28.873 72.354  69.266 1.00 76.88  ? 175 ASN A N   1 
ATOM   1301  C CA  . ASN A 1 167 ? -29.639 72.477  70.490 1.00 90.57  ? 175 ASN A CA  1 
ATOM   1302  C C   . ASN A 1 167 ? -29.523 73.919  70.962 1.00 91.33  ? 175 ASN A C   1 
ATOM   1303  O O   . ASN A 1 167 ? -28.427 74.450  71.247 1.00 88.77  ? 175 ASN A O   1 
ATOM   1304  C CB  . ASN A 1 167 ? -28.922 71.737  71.605 1.00 117.36 ? 175 ASN A CB  1 
ATOM   1305  C CG  . ASN A 1 167 ? -29.763 71.568  72.830 1.00 94.82  ? 175 ASN A CG  1 
ATOM   1306  O OD1 . ASN A 1 167 ? -30.307 72.554  73.370 1.00 129.93 ? 175 ASN A OD1 1 
ATOM   1307  N ND2 . ASN A 1 167 ? -29.700 70.330  73.308 1.00 99.68  ? 175 ASN A ND2 1 
ATOM   1308  N N   . PRO A 1 168 ? -30.661 74.634  71.062 1.00 75.02  ? 176 PRO A N   1 
ATOM   1309  C CA  . PRO A 1 168 ? -30.570 76.057  71.406 1.00 72.69  ? 176 PRO A CA  1 
ATOM   1310  C C   . PRO A 1 168 ? -30.124 76.266  72.862 1.00 89.95  ? 176 PRO A C   1 
ATOM   1311  O O   . PRO A 1 168 ? -29.653 77.339  73.204 1.00 121.41 ? 176 PRO A O   1 
ATOM   1312  C CB  . PRO A 1 168 ? -31.910 76.671  71.010 1.00 59.75  ? 176 PRO A CB  1 
ATOM   1313  C CG  . PRO A 1 168 ? -32.833 75.445  71.031 1.00 67.05  ? 176 PRO A CG  1 
ATOM   1314  C CD  . PRO A 1 168 ? -32.034 74.133  70.862 1.00 59.98  ? 176 PRO A CD  1 
ATOM   1315  N N   . ASP A 1 169 ? -30.214 75.232  73.702 1.00 82.74  ? 177 ASP A N   1 
ATOM   1316  C CA  . ASP A 1 169 ? -29.851 75.380  75.100 1.00 72.51  ? 177 ASP A CA  1 
ATOM   1317  C C   . ASP A 1 169 ? -28.367 75.186  75.328 1.00 83.12  ? 177 ASP A C   1 
ATOM   1318  O O   . ASP A 1 169 ? -27.843 75.879  76.180 1.00 141.51 ? 177 ASP A O   1 
ATOM   1319  C CB  . ASP A 1 169 ? -30.746 74.564  76.006 1.00 75.67  ? 177 ASP A CB  1 
ATOM   1320  C CG  . ASP A 1 169 ? -32.209 74.879  75.746 1.00 112.59 ? 177 ASP A CG  1 
ATOM   1321  O OD1 . ASP A 1 169 ? -32.495 76.071  75.472 1.00 103.37 ? 177 ASP A OD1 1 
ATOM   1322  O OD2 . ASP A 1 169 ? -33.043 73.945  75.787 1.00 142.95 ? 177 ASP A OD2 1 
ATOM   1323  N N   . THR A 1 170 ? -27.685 74.330  74.547 1.00 74.09  ? 178 THR A N   1 
ATOM   1324  C CA  . THR A 1 170 ? -26.288 73.976  74.760 1.00 63.02  ? 178 THR A CA  1 
ATOM   1325  C C   . THR A 1 170 ? -25.424 74.712  73.739 1.00 72.58  ? 178 THR A C   1 
ATOM   1326  O O   . THR A 1 170 ? -24.232 74.931  73.966 1.00 78.94  ? 178 THR A O   1 
ATOM   1327  C CB  . THR A 1 170 ? -26.094 72.452  74.641 1.00 72.51  ? 178 THR A CB  1 
ATOM   1328  O OG1 . THR A 1 170 ? -26.212 71.895  73.324 1.00 69.42  ? 178 THR A OG1 1 
ATOM   1329  C CG2 . THR A 1 170 ? -26.967 71.693  75.628 1.00 54.04  ? 178 THR A CG2 1 
ATOM   1330  N N   . GLY A 1 171 ? -26.027 75.058  72.594 1.00 70.75  ? 179 GLY A N   1 
ATOM   1331  C CA  . GLY A 1 171 ? -25.256 75.648  71.507 1.00 83.95  ? 179 GLY A CA  1 
ATOM   1332  C C   . GLY A 1 171 ? -24.485 74.594  70.706 1.00 85.65  ? 179 GLY A C   1 
ATOM   1333  O O   . GLY A 1 171 ? -23.730 74.965  69.820 1.00 83.82  ? 179 GLY A O   1 
ATOM   1334  N N   . TYR A 1 172 ? -24.736 73.304  70.994 1.00 81.63  ? 180 TYR A N   1 
ATOM   1335  C CA  . TYR A 1 172 ? -24.147 72.185  70.266 1.00 67.99  ? 180 TYR A CA  1 
ATOM   1336  C C   . TYR A 1 172 ? -25.121 71.626  69.240 1.00 82.78  ? 180 TYR A C   1 
ATOM   1337  O O   . TYR A 1 172 ? -26.324 71.752  69.334 1.00 95.60  ? 180 TYR A O   1 
ATOM   1338  C CB  . TYR A 1 172 ? -23.750 71.052  71.219 1.00 69.60  ? 180 TYR A CB  1 
ATOM   1339  C CG  . TYR A 1 172 ? -22.478 71.359  72.004 1.00 80.35  ? 180 TYR A CG  1 
ATOM   1340  C CD1 . TYR A 1 172 ? -22.521 72.141  73.170 1.00 70.29  ? 180 TYR A CD1 1 
ATOM   1341  C CD2 . TYR A 1 172 ? -21.234 70.930  71.546 1.00 61.95  ? 180 TYR A CD2 1 
ATOM   1342  C CE1 . TYR A 1 172 ? -21.370 72.414  73.891 1.00 78.18  ? 180 TYR A CE1 1 
ATOM   1343  C CE2 . TYR A 1 172 ? -20.077 71.243  72.232 1.00 63.92  ? 180 TYR A CE2 1 
ATOM   1344  C CZ  . TYR A 1 172 ? -20.145 71.970  73.410 1.00 92.75  ? 180 TYR A CZ  1 
ATOM   1345  O OH  . TYR A 1 172 ? -18.973 72.269  74.049 1.00 96.07  ? 180 TYR A OH  1 
ATOM   1346  N N   . ILE A 1 173 ? -24.585 70.936  68.249 1.00 100.71 ? 181 ILE A N   1 
ATOM   1347  C CA  . ILE A 1 173 ? -25.410 70.166  67.327 1.00 82.17  ? 181 ILE A CA  1 
ATOM   1348  C C   . ILE A 1 173 ? -26.100 69.083  68.140 1.00 77.37  ? 181 ILE A C   1 
ATOM   1349  O O   . ILE A 1 173 ? -25.485 68.409  68.950 1.00 75.17  ? 181 ILE A O   1 
ATOM   1350  C CB  . ILE A 1 173 ? -24.524 69.558  66.222 1.00 67.25  ? 181 ILE A CB  1 
ATOM   1351  C CG1 . ILE A 1 173 ? -24.091 70.668  65.250 1.00 54.11  ? 181 ILE A CG1 1 
ATOM   1352  C CG2 . ILE A 1 173 ? -25.249 68.444  65.485 1.00 56.82  ? 181 ILE A CG2 1 
ATOM   1353  C CD1 . ILE A 1 173 ? -22.984 70.238  64.318 1.00 61.49  ? 181 ILE A CD1 1 
ATOM   1354  N N   . ASN A 1 174 ? -27.387 68.933  67.879 1.00 77.76  ? 182 ASN A N   1 
ATOM   1355  C CA  . ASN A 1 174 ? -28.247 67.964  68.513 1.00 69.23  ? 182 ASN A CA  1 
ATOM   1356  C C   . ASN A 1 174 ? -28.206 66.653  67.727 1.00 81.57  ? 182 ASN A C   1 
ATOM   1357  O O   . ASN A 1 174 ? -29.061 66.396  66.848 1.00 101.40 ? 182 ASN A O   1 
ATOM   1358  C CB  . ASN A 1 174 ? -29.628 68.549  68.348 1.00 75.44  ? 182 ASN A CB  1 
ATOM   1359  C CG  . ASN A 1 174 ? -30.628 67.854  69.199 1.00 79.36  ? 182 ASN A CG  1 
ATOM   1360  O OD1 . ASN A 1 174 ? -30.593 66.627  69.298 1.00 77.13  ? 182 ASN A OD1 1 
ATOM   1361  N ND2 . ASN A 1 174 ? -31.522 68.647  69.767 1.00 74.44  ? 182 ASN A ND2 1 
ATOM   1362  N N   . TYR A 1 175 ? -27.147 65.870  67.985 1.00 63.58  ? 183 TYR A N   1 
ATOM   1363  C CA  . TYR A 1 175 ? -26.943 64.642  67.227 1.00 76.50  ? 183 TYR A CA  1 
ATOM   1364  C C   . TYR A 1 175 ? -28.120 63.678  67.378 1.00 87.82  ? 183 TYR A C   1 
ATOM   1365  O O   . TYR A 1 175 ? -28.388 62.866  66.492 1.00 113.35 ? 183 TYR A O   1 
ATOM   1366  C CB  . TYR A 1 175 ? -25.592 63.984  67.464 1.00 65.83  ? 183 TYR A CB  1 
ATOM   1367  C CG  . TYR A 1 175 ? -24.421 64.901  67.114 1.00 62.76  ? 183 TYR A CG  1 
ATOM   1368  C CD1 . TYR A 1 175 ? -23.869 64.901  65.856 1.00 62.64  ? 183 TYR A CD1 1 
ATOM   1369  C CD2 . TYR A 1 175 ? -23.812 65.708  68.072 1.00 87.33  ? 183 TYR A CD2 1 
ATOM   1370  C CE1 . TYR A 1 175 ? -22.788 65.704  65.542 1.00 96.14  ? 183 TYR A CE1 1 
ATOM   1371  C CE2 . TYR A 1 175 ? -22.711 66.500  67.792 1.00 96.87  ? 183 TYR A CE2 1 
ATOM   1372  C CZ  . TYR A 1 175 ? -22.202 66.510  66.513 1.00 110.62 ? 183 TYR A CZ  1 
ATOM   1373  O OH  . TYR A 1 175 ? -21.122 67.321  66.294 1.00 106.12 ? 183 TYR A OH  1 
ATOM   1374  N N   . ASP A 1 176 ? -28.858 63.828  68.480 1.00 73.77  ? 184 ASP A N   1 
ATOM   1375  C CA  . ASP A 1 176 ? -29.988 62.928  68.682 1.00 88.05  ? 184 ASP A CA  1 
ATOM   1376  C C   . ASP A 1 176 ? -31.122 63.247  67.728 1.00 80.60  ? 184 ASP A C   1 
ATOM   1377  O O   . ASP A 1 176 ? -31.728 62.336  67.172 1.00 69.09  ? 184 ASP A O   1 
ATOM   1378  C CB  . ASP A 1 176 ? -30.472 62.866  70.122 1.00 91.82  ? 184 ASP A CB  1 
ATOM   1379  C CG  . ASP A 1 176 ? -29.406 62.397  71.088 1.00 97.33  ? 184 ASP A CG  1 
ATOM   1380  O OD1 . ASP A 1 176 ? -28.296 62.026  70.655 1.00 144.10 ? 184 ASP A OD1 1 
ATOM   1381  O OD2 . ASP A 1 176 ? -29.671 62.435  72.260 1.00 70.92  ? 184 ASP A OD2 1 
ATOM   1382  N N   . GLN A 1 177 ? -31.422 64.539  67.586 1.00 96.81  ? 185 GLN A N   1 
ATOM   1383  C CA  . GLN A 1 177 ? -32.471 64.968  66.673 1.00 118.79 ? 185 GLN A CA  1 
ATOM   1384  C C   . GLN A 1 177 ? -32.124 64.428  65.281 1.00 94.67  ? 185 GLN A C   1 
ATOM   1385  O O   . GLN A 1 177 ? -32.981 63.811  64.648 1.00 67.91  ? 185 GLN A O   1 
ATOM   1386  C CB  . GLN A 1 177 ? -32.849 66.455  66.797 1.00 98.18  ? 185 GLN A CB  1 
ATOM   1387  C CG  . GLN A 1 177 ? -33.709 66.947  65.625 1.00 89.36  ? 185 GLN A CG  1 
ATOM   1388  C CD  . GLN A 1 177 ? -34.785 67.958  65.963 1.00 84.07  ? 185 GLN A CD  1 
ATOM   1389  O OE1 . GLN A 1 177 ? -34.479 69.105  66.330 1.00 117.93 ? 185 GLN A OE1 1 
ATOM   1390  N NE2 . GLN A 1 177 ? -36.052 67.572  65.777 1.00 45.54  ? 185 GLN A NE2 1 
ATOM   1391  N N   . LEU A 1 178 ? -30.837 64.549  64.909 1.00 88.32  ? 186 LEU A N   1 
ATOM   1392  C CA  . LEU A 1 178 ? -30.340 64.098  63.623 1.00 91.91  ? 186 LEU A CA  1 
ATOM   1393  C C   . LEU A 1 178 ? -30.744 62.643  63.422 1.00 84.50  ? 186 LEU A C   1 
ATOM   1394  O O   . LEU A 1 178 ? -31.339 62.277  62.404 1.00 78.24  ? 186 LEU A O   1 
ATOM   1395  C CB  . LEU A 1 178 ? -28.827 64.261  63.450 1.00 72.99  ? 186 LEU A CB  1 
ATOM   1396  C CG  . LEU A 1 178 ? -28.270 63.760  62.095 1.00 60.06  ? 186 LEU A CG  1 
ATOM   1397  C CD1 . LEU A 1 178 ? -29.125 63.988  60.845 1.00 40.85  ? 186 LEU A CD1 1 
ATOM   1398  C CD2 . LEU A 1 178 ? -26.838 64.202  61.751 1.00 52.27  ? 186 LEU A CD2 1 
ATOM   1399  N N   . GLU A 1 179 ? -30.381 61.845  64.418 1.00 87.06  ? 187 GLU A N   1 
ATOM   1400  C CA  . GLU A 1 179 ? -30.579 60.411  64.368 1.00 96.43  ? 187 GLU A CA  1 
ATOM   1401  C C   . GLU A 1 179 ? -32.036 60.067  64.043 1.00 88.52  ? 187 GLU A C   1 
ATOM   1402  O O   . GLU A 1 179 ? -32.287 59.221  63.131 1.00 77.86  ? 187 GLU A O   1 
ATOM   1403  C CB  . GLU A 1 179 ? -30.093 59.766  65.663 1.00 84.61  ? 187 GLU A CB  1 
ATOM   1404  C CG  . GLU A 1 179 ? -29.825 58.288  65.387 1.00 75.77  ? 187 GLU A CG  1 
ATOM   1405  C CD  . GLU A 1 179 ? -29.601 57.423  66.582 1.00 66.33  ? 187 GLU A CD  1 
ATOM   1406  O OE1 . GLU A 1 179 ? -28.519 56.803  66.626 1.00 105.49 ? 187 GLU A OE1 1 
ATOM   1407  O OE2 . GLU A 1 179 ? -30.525 57.375  67.416 1.00 53.18  ? 187 GLU A OE2 1 
ATOM   1408  N N   . GLU A 1 180 ? -32.940 60.706  64.838 1.00 50.13  ? 188 GLU A N   1 
ATOM   1409  C CA  . GLU A 1 180 ? -34.372 60.457  64.723 1.00 81.65  ? 188 GLU A CA  1 
ATOM   1410  C C   . GLU A 1 180 ? -34.900 60.881  63.355 1.00 84.01  ? 188 GLU A C   1 
ATOM   1411  O O   . GLU A 1 180 ? -35.535 60.081  62.662 1.00 87.05  ? 188 GLU A O   1 
ATOM   1412  C CB  . GLU A 1 180 ? -35.182 60.948  65.925 1.00 88.29  ? 188 GLU A CB  1 
ATOM   1413  C CG  . GLU A 1 180 ? -35.401 59.801  66.915 1.00 112.49 ? 188 GLU A CG  1 
ATOM   1414  C CD  . GLU A 1 180 ? -35.069 60.190  68.350 1.00 128.73 ? 188 GLU A CD  1 
ATOM   1415  O OE1 . GLU A 1 180 ? -35.784 61.112  68.806 1.00 132.43 ? 188 GLU A OE1 1 
ATOM   1416  O OE2 . GLU A 1 180 ? -34.121 59.622  68.995 1.00 95.82  ? 188 GLU A OE2 1 
ATOM   1417  N N   . ASN A 1 181 ? -34.581 62.120  62.970 1.00 54.85  ? 189 ASN A N   1 
ATOM   1418  C CA  . ASN A 1 181 ? -35.110 62.682  61.745 1.00 51.79  ? 189 ASN A CA  1 
ATOM   1419  C C   . ASN A 1 181 ? -34.545 61.881  60.564 1.00 68.60  ? 189 ASN A C   1 
ATOM   1420  O O   . ASN A 1 181 ? -35.269 61.659  59.575 1.00 57.62  ? 189 ASN A O   1 
ATOM   1421  C CB  . ASN A 1 181 ? -34.652 64.113  61.468 1.00 68.40  ? 189 ASN A CB  1 
ATOM   1422  C CG  . ASN A 1 181 ? -35.319 65.178  62.287 1.00 85.69  ? 189 ASN A CG  1 
ATOM   1423  O OD1 . ASN A 1 181 ? -36.370 64.864  62.890 1.00 71.27  ? 189 ASN A OD1 1 
ATOM   1424  N ND2 . ASN A 1 181 ? -34.742 66.400  62.234 1.00 60.97  ? 189 ASN A ND2 1 
ATOM   1425  N N   . ALA A 1 182 ? -33.257 61.473  60.633 1.00 61.89  ? 190 ALA A N   1 
ATOM   1426  C CA  . ALA A 1 182 ? -32.663 60.736  59.534 1.00 58.77  ? 190 ALA A CA  1 
ATOM   1427  C C   . ALA A 1 182 ? -33.481 59.485  59.268 1.00 64.55  ? 190 ALA A C   1 
ATOM   1428  O O   . ALA A 1 182 ? -33.733 59.157  58.114 1.00 76.61  ? 190 ALA A O   1 
ATOM   1429  C CB  . ALA A 1 182 ? -31.220 60.453  59.768 1.00 61.06  ? 190 ALA A CB  1 
ATOM   1430  N N   . ARG A 1 183 ? -33.984 58.843  60.326 1.00 70.84  ? 191 ARG A N   1 
ATOM   1431  C CA  . ARG A 1 183 ? -34.774 57.628  60.124 1.00 71.13  ? 191 ARG A CA  1 
ATOM   1432  C C   . ARG A 1 183 ? -36.144 57.912  59.519 1.00 70.55  ? 191 ARG A C   1 
ATOM   1433  O O   . ARG A 1 183 ? -36.681 57.006  58.908 1.00 87.42  ? 191 ARG A O   1 
ATOM   1434  C CB  . ARG A 1 183 ? -34.934 56.791  61.384 1.00 65.32  ? 191 ARG A CB  1 
ATOM   1435  C CG  . ARG A 1 183 ? -33.539 56.255  61.689 1.00 76.90  ? 191 ARG A CG  1 
ATOM   1436  C CD  . ARG A 1 183 ? -33.517 55.164  62.761 1.00 85.05  ? 191 ARG A CD  1 
ATOM   1437  N NE  . ARG A 1 183 ? -34.127 55.768  63.946 1.00 66.32  ? 191 ARG A NE  1 
ATOM   1438  C CZ  . ARG A 1 183 ? -33.460 55.999  65.054 1.00 70.77  ? 191 ARG A CZ  1 
ATOM   1439  N NH1 . ARG A 1 183 ? -34.078 56.753  65.966 1.00 73.92  ? 191 ARG A NH1 1 
ATOM   1440  N NH2 . ARG A 1 183 ? -32.179 55.574  65.145 1.00 53.94  ? 191 ARG A NH2 1 
ATOM   1441  N N   . LEU A 1 184 ? -36.664 59.138  59.668 1.00 54.39  ? 192 LEU A N   1 
ATOM   1442  C CA  . LEU A 1 184 ? -37.891 59.570  58.999 1.00 78.82  ? 192 LEU A CA  1 
ATOM   1443  C C   . LEU A 1 184 ? -37.693 59.953  57.524 1.00 85.82  ? 192 LEU A C   1 
ATOM   1444  O O   . LEU A 1 184 ? -38.479 59.582  56.643 1.00 77.47  ? 192 LEU A O   1 
ATOM   1445  C CB  . LEU A 1 184 ? -38.317 60.850  59.699 1.00 67.73  ? 192 LEU A CB  1 
ATOM   1446  C CG  . LEU A 1 184 ? -38.700 60.733  61.175 1.00 69.15  ? 192 LEU A CG  1 
ATOM   1447  C CD1 . LEU A 1 184 ? -38.937 62.159  61.762 1.00 51.42  ? 192 LEU A CD1 1 
ATOM   1448  C CD2 . LEU A 1 184 ? -39.899 59.790  61.367 1.00 52.50  ? 192 LEU A CD2 1 
ATOM   1449  N N   . PHE A 1 185 ? -36.676 60.791  57.303 1.00 65.92  ? 193 PHE A N   1 
ATOM   1450  C CA  . PHE A 1 185 ? -36.443 61.395  55.999 1.00 64.96  ? 193 PHE A CA  1 
ATOM   1451  C C   . PHE A 1 185 ? -35.633 60.502  55.040 1.00 69.56  ? 193 PHE A C   1 
ATOM   1452  O O   . PHE A 1 185 ? -35.752 60.687  53.840 1.00 56.99  ? 193 PHE A O   1 
ATOM   1453  C CB  . PHE A 1 185 ? -35.701 62.688  56.337 1.00 65.58  ? 193 PHE A CB  1 
ATOM   1454  C CG  . PHE A 1 185 ? -35.357 63.570  55.143 1.00 60.97  ? 193 PHE A CG  1 
ATOM   1455  C CD1 . PHE A 1 185 ? -36.370 64.131  54.383 1.00 57.20  ? 193 PHE A CD1 1 
ATOM   1456  C CD2 . PHE A 1 185 ? -34.034 63.834  54.792 1.00 73.47  ? 193 PHE A CD2 1 
ATOM   1457  C CE1 . PHE A 1 185 ? -36.090 64.901  53.286 1.00 58.59  ? 193 PHE A CE1 1 
ATOM   1458  C CE2 . PHE A 1 185 ? -33.767 64.641  53.687 1.00 99.87  ? 193 PHE A CE2 1 
ATOM   1459  C CZ  . PHE A 1 185 ? -34.801 65.207  52.975 1.00 81.08  ? 193 PHE A CZ  1 
ATOM   1460  N N   . HIS A 1 186 ? -34.835 59.545  55.562 1.00 71.04  ? 194 HIS A N   1 
ATOM   1461  C CA  . HIS A 1 186 ? -33.920 58.664  54.818 1.00 71.70  ? 194 HIS A CA  1 
ATOM   1462  C C   . HIS A 1 186 ? -32.969 59.465  53.923 1.00 56.86  ? 194 HIS A C   1 
ATOM   1463  O O   . HIS A 1 186 ? -33.124 59.513  52.706 1.00 62.50  ? 194 HIS A O   1 
ATOM   1464  C CB  . HIS A 1 186 ? -34.704 57.616  54.015 1.00 77.74  ? 194 HIS A CB  1 
ATOM   1465  C CG  . HIS A 1 186 ? -35.837 57.015  54.750 1.00 79.36  ? 194 HIS A CG  1 
ATOM   1466  N ND1 . HIS A 1 186 ? -35.567 55.948  55.568 1.00 104.18 ? 194 HIS A ND1 1 
ATOM   1467  C CD2 . HIS A 1 186 ? -37.156 57.192  54.810 1.00 80.98  ? 194 HIS A CD2 1 
ATOM   1468  C CE1 . HIS A 1 186 ? -36.694 55.532  56.118 1.00 111.40 ? 194 HIS A CE1 1 
ATOM   1469  N NE2 . HIS A 1 186 ? -37.665 56.286  55.679 1.00 84.22  ? 194 HIS A NE2 1 
ATOM   1470  N N   . PRO A 1 187 ? -32.000 60.212  54.476 1.00 55.55  ? 195 PRO A N   1 
ATOM   1471  C CA  . PRO A 1 187 ? -31.021 60.953  53.667 1.00 73.86  ? 195 PRO A CA  1 
ATOM   1472  C C   . PRO A 1 187 ? -30.161 59.985  52.894 1.00 68.90  ? 195 PRO A C   1 
ATOM   1473  O O   . PRO A 1 187 ? -29.902 58.932  53.450 1.00 66.35  ? 195 PRO A O   1 
ATOM   1474  C CB  . PRO A 1 187 ? -30.134 61.708  54.689 1.00 77.04  ? 195 PRO A CB  1 
ATOM   1475  C CG  . PRO A 1 187 ? -30.354 60.993  56.000 1.00 69.47  ? 195 PRO A CG  1 
ATOM   1476  C CD  . PRO A 1 187 ? -31.802 60.477  55.905 1.00 69.92  ? 195 PRO A CD  1 
ATOM   1477  N N   . LYS A 1 188 ? -29.803 60.337  51.643 1.00 72.18  ? 196 LYS A N   1 
ATOM   1478  C CA  . LYS A 1 188 ? -28.885 59.551  50.808 1.00 88.30  ? 196 LYS A CA  1 
ATOM   1479  C C   . LYS A 1 188 ? -27.468 59.991  51.206 1.00 90.24  ? 196 LYS A C   1 
ATOM   1480  O O   . LYS A 1 188 ? -26.521 59.199  51.096 1.00 64.15  ? 196 LYS A O   1 
ATOM   1481  C CB  . LYS A 1 188 ? -29.024 59.796  49.286 1.00 99.49  ? 196 LYS A CB  1 
ATOM   1482  C CG  . LYS A 1 188 ? -29.584 58.893  48.096 1.00 107.39 ? 196 LYS A CG  1 
ATOM   1483  C CD  . LYS A 1 188 ? -29.473 57.373  47.847 1.00 121.25 ? 196 LYS A CD  1 
ATOM   1484  C CE  . LYS A 1 188 ? -28.218 56.539  48.128 1.00 85.02  ? 196 LYS A CE  1 
ATOM   1485  N NZ  . LYS A 1 188 ? -28.374 55.292  48.918 1.00 45.22  ? 196 LYS A NZ  1 
ATOM   1486  N N   . LEU A 1 189 ? -27.350 61.254  51.679 1.00 81.74  ? 197 LEU A N   1 
ATOM   1487  C CA  . LEU A 1 189 ? -26.072 61.885  52.003 1.00 80.73  ? 197 LEU A CA  1 
ATOM   1488  C C   . LEU A 1 189 ? -26.217 62.857  53.183 1.00 80.44  ? 197 LEU A C   1 
ATOM   1489  O O   . LEU A 1 189 ? -27.183 63.605  53.240 1.00 102.58 ? 197 LEU A O   1 
ATOM   1490  C CB  . LEU A 1 189 ? -25.466 62.536  50.763 1.00 56.42  ? 197 LEU A CB  1 
ATOM   1491  C CG  . LEU A 1 189 ? -24.120 63.265  50.959 1.00 72.72  ? 197 LEU A CG  1 
ATOM   1492  C CD1 . LEU A 1 189 ? -23.252 63.293  49.688 1.00 75.76  ? 197 LEU A CD1 1 
ATOM   1493  C CD2 . LEU A 1 189 ? -24.154 64.665  51.592 1.00 62.02  ? 197 LEU A CD2 1 
ATOM   1494  N N   . ILE A 1 190 ? -25.286 62.808  54.147 1.00 46.06  ? 198 ILE A N   1 
ATOM   1495  C CA  . ILE A 1 190 ? -25.353 63.644  55.330 1.00 41.25  ? 198 ILE A CA  1 
ATOM   1496  C C   . ILE A 1 190 ? -24.061 64.455  55.373 1.00 57.25  ? 198 ILE A C   1 
ATOM   1497  O O   . ILE A 1 190 ? -22.946 63.888  55.351 1.00 72.43  ? 198 ILE A O   1 
ATOM   1498  C CB  . ILE A 1 190 ? -25.464 62.834  56.632 1.00 32.81  ? 198 ILE A CB  1 
ATOM   1499  C CG1 . ILE A 1 190 ? -26.671 61.907  56.688 1.00 38.76  ? 198 ILE A CG1 1 
ATOM   1500  C CG2 . ILE A 1 190 ? -25.424 63.759  57.839 1.00 34.72  ? 198 ILE A CG2 1 
ATOM   1501  C CD1 . ILE A 1 190 ? -26.789 61.091  57.995 1.00 38.24  ? 198 ILE A CD1 1 
ATOM   1502  N N   . ILE A 1 191 ? -24.214 65.776  55.555 1.00 47.73  ? 199 ILE A N   1 
ATOM   1503  C CA  . ILE A 1 191 ? -23.074 66.664  55.536 1.00 50.45  ? 199 ILE A CA  1 
ATOM   1504  C C   . ILE A 1 191 ? -22.523 66.866  56.953 1.00 64.02  ? 199 ILE A C   1 
ATOM   1505  O O   . ILE A 1 191 ? -23.255 67.200  57.880 1.00 70.45  ? 199 ILE A O   1 
ATOM   1506  C CB  . ILE A 1 191 ? -23.511 67.964  54.846 1.00 55.79  ? 199 ILE A CB  1 
ATOM   1507  C CG1 . ILE A 1 191 ? -23.948 67.686  53.445 1.00 52.62  ? 199 ILE A CG1 1 
ATOM   1508  C CG2 . ILE A 1 191 ? -22.409 69.014  54.803 1.00 72.67  ? 199 ILE A CG2 1 
ATOM   1509  C CD1 . ILE A 1 191 ? -24.660 68.855  52.792 1.00 58.15  ? 199 ILE A CD1 1 
ATOM   1510  N N   . ALA A 1 192 ? -21.201 66.729  57.099 1.00 68.01  ? 200 ALA A N   1 
ATOM   1511  C CA  . ALA A 1 192 ? -20.506 66.991  58.348 1.00 68.57  ? 200 ALA A CA  1 
ATOM   1512  C C   . ALA A 1 192 ? -19.578 68.183  58.114 1.00 82.09  ? 200 ALA A C   1 
ATOM   1513  O O   . ALA A 1 192 ? -18.429 68.069  57.671 1.00 64.95  ? 200 ALA A O   1 
ATOM   1514  C CB  . ALA A 1 192 ? -19.716 65.765  58.747 1.00 63.78  ? 200 ALA A CB  1 
ATOM   1515  N N   . GLY A 1 193 ? -20.114 69.366  58.391 1.00 92.69  ? 201 GLY A N   1 
ATOM   1516  C CA  . GLY A 1 193 ? -19.427 70.584  57.993 1.00 81.14  ? 201 GLY A CA  1 
ATOM   1517  C C   . GLY A 1 193 ? -20.286 71.762  58.410 1.00 83.80  ? 201 GLY A C   1 
ATOM   1518  O O   . GLY A 1 193 ? -21.539 71.656  58.444 1.00 77.94  ? 201 GLY A O   1 
ATOM   1519  N N   . THR A 1 194 ? -19.573 72.839  58.778 1.00 70.95  ? 202 THR A N   1 
ATOM   1520  C CA  . THR A 1 194 ? -20.237 74.038  59.278 1.00 70.03  ? 202 THR A CA  1 
ATOM   1521  C C   . THR A 1 194 ? -19.597 75.294  58.682 1.00 73.87  ? 202 THR A C   1 
ATOM   1522  O O   . THR A 1 194 ? -18.451 75.283  58.189 1.00 51.49  ? 202 THR A O   1 
ATOM   1523  C CB  . THR A 1 194 ? -20.294 74.114  60.806 1.00 70.42  ? 202 THR A CB  1 
ATOM   1524  O OG1 . THR A 1 194 ? -18.964 74.374  61.223 1.00 79.10  ? 202 THR A OG1 1 
ATOM   1525  C CG2 . THR A 1 194 ? -20.762 72.829  61.470 1.00 76.96  ? 202 THR A CG2 1 
ATOM   1526  N N   . SER A 1 195 ? -20.385 76.383  58.733 1.00 75.65  ? 203 SER A N   1 
ATOM   1527  C CA  . SER A 1 195 ? -19.853 77.678  58.370 1.00 85.86  ? 203 SER A CA  1 
ATOM   1528  C C   . SER A 1 195 ? -19.709 78.549  59.614 1.00 91.32  ? 203 SER A C   1 
ATOM   1529  O O   . SER A 1 195 ? -19.009 79.549  59.594 1.00 92.12  ? 203 SER A O   1 
ATOM   1530  C CB  . SER A 1 195 ? -20.703 78.323  57.348 1.00 96.61  ? 203 SER A CB  1 
ATOM   1531  O OG  . SER A 1 195 ? -19.811 78.970  56.445 1.00 142.36 ? 203 SER A OG  1 
ATOM   1532  N N   . CYS A 1 196 ? -20.369 78.168  60.703 1.00 87.58  ? 204 CYS A N   1 
ATOM   1533  C CA  . CYS A 1 196 ? -20.296 78.930  61.927 1.00 81.15  ? 204 CYS A CA  1 
ATOM   1534  C C   . CYS A 1 196 ? -20.599 78.005  63.105 1.00 87.09  ? 204 CYS A C   1 
ATOM   1535  O O   . CYS A 1 196 ? -21.727 78.009  63.584 1.00 93.13  ? 204 CYS A O   1 
ATOM   1536  C CB  . CYS A 1 196 ? -21.354 80.034  61.886 1.00 86.42  ? 204 CYS A CB  1 
ATOM   1537  S SG  . CYS A 1 196 ? -21.377 81.162  63.311 1.00 85.20  ? 204 CYS A SG  1 
ATOM   1538  N N   . TYR A 1 197 ? -19.600 77.242  63.585 1.00 86.34  ? 205 TYR A N   1 
ATOM   1539  C CA  . TYR A 1 197 ? -19.752 76.429  64.798 1.00 76.09  ? 205 TYR A CA  1 
ATOM   1540  C C   . TYR A 1 197 ? -18.410 76.340  65.531 1.00 77.01  ? 205 TYR A C   1 
ATOM   1541  O O   . TYR A 1 197 ? -17.380 76.096  64.930 1.00 56.76  ? 205 TYR A O   1 
ATOM   1542  C CB  . TYR A 1 197 ? -20.274 75.082  64.304 1.00 56.46  ? 205 TYR A CB  1 
ATOM   1543  C CG  . TYR A 1 197 ? -20.632 74.038  65.333 1.00 58.86  ? 205 TYR A CG  1 
ATOM   1544  C CD1 . TYR A 1 197 ? -21.792 74.155  66.093 1.00 80.35  ? 205 TYR A CD1 1 
ATOM   1545  C CD2 . TYR A 1 197 ? -19.898 72.863  65.451 1.00 70.53  ? 205 TYR A CD2 1 
ATOM   1546  C CE1 . TYR A 1 197 ? -22.173 73.164  66.998 1.00 71.29  ? 205 TYR A CE1 1 
ATOM   1547  C CE2 . TYR A 1 197 ? -20.262 71.860  66.343 1.00 72.17  ? 205 TYR A CE2 1 
ATOM   1548  C CZ  . TYR A 1 197 ? -21.396 72.015  67.115 1.00 74.29  ? 205 TYR A CZ  1 
ATOM   1549  O OH  . TYR A 1 197 ? -21.614 71.004  67.991 1.00 79.42  ? 205 TYR A OH  1 
ATOM   1550  N N   . SER A 1 198 ? -18.386 76.583  66.840 1.00 99.57  ? 206 SER A N   1 
ATOM   1551  C CA  . SER A 1 198 ? -17.140 76.763  67.582 1.00 80.96  ? 206 SER A CA  1 
ATOM   1552  C C   . SER A 1 198 ? -16.511 75.411  67.905 1.00 71.78  ? 206 SER A C   1 
ATOM   1553  O O   . SER A 1 198 ? -15.451 75.418  68.515 1.00 66.65  ? 206 SER A O   1 
ATOM   1554  C CB  . SER A 1 198 ? -17.418 77.374  68.952 1.00 65.78  ? 206 SER A CB  1 
ATOM   1555  O OG  . SER A 1 198 ? -18.403 78.398  69.126 1.00 62.32  ? 206 SER A OG  1 
ATOM   1556  N N   . ARG A 1 199 ? -17.180 74.285  67.582 1.00 63.71  ? 207 ARG A N   1 
ATOM   1557  C CA  . ARG A 1 199 ? -16.824 73.007  68.188 1.00 73.30  ? 207 ARG A CA  1 
ATOM   1558  C C   . ARG A 1 199 ? -16.498 71.958  67.138 1.00 77.61  ? 207 ARG A C   1 
ATOM   1559  O O   . ARG A 1 199 ? -16.815 72.162  65.975 1.00 82.18  ? 207 ARG A O   1 
ATOM   1560  C CB  . ARG A 1 199 ? -17.926 72.426  69.069 1.00 73.33  ? 207 ARG A CB  1 
ATOM   1561  C CG  . ARG A 1 199 ? -18.225 73.311  70.267 1.00 68.74  ? 207 ARG A CG  1 
ATOM   1562  C CD  . ARG A 1 199 ? -16.973 73.498  71.042 1.00 77.10  ? 207 ARG A CD  1 
ATOM   1563  N NE  . ARG A 1 199 ? -17.325 74.319  72.194 1.00 102.60 ? 207 ARG A NE  1 
ATOM   1564  C CZ  . ARG A 1 199 ? -16.501 74.779  73.117 1.00 83.85  ? 207 ARG A CZ  1 
ATOM   1565  N NH1 . ARG A 1 199 ? -15.226 74.453  73.139 1.00 89.71  ? 207 ARG A NH1 1 
ATOM   1566  N NH2 . ARG A 1 199 ? -17.031 75.525  74.049 1.00 76.74  ? 207 ARG A NH2 1 
ATOM   1567  N N   . ASN A 1 200 ? -15.842 70.854  67.565 1.00 64.84  ? 208 ASN A N   1 
ATOM   1568  C CA  . ASN A 1 200 ? -15.565 69.778  66.630 1.00 84.76  ? 208 ASN A CA  1 
ATOM   1569  C C   . ASN A 1 200 ? -16.839 69.010  66.297 1.00 76.19  ? 208 ASN A C   1 
ATOM   1570  O O   . ASN A 1 200 ? -17.836 69.088  66.996 1.00 51.16  ? 208 ASN A O   1 
ATOM   1571  C CB  . ASN A 1 200 ? -14.554 68.798  67.198 1.00 96.80  ? 208 ASN A CB  1 
ATOM   1572  C CG  . ASN A 1 200 ? -13.242 69.486  67.435 1.00 107.56 ? 208 ASN A CG  1 
ATOM   1573  O OD1 . ASN A 1 200 ? -12.760 70.213  66.565 1.00 141.94 ? 208 ASN A OD1 1 
ATOM   1574  N ND2 . ASN A 1 200 ? -12.686 69.307  68.617 1.00 147.67 ? 208 ASN A ND2 1 
ATOM   1575  N N   . LEU A 1 201 ? -16.833 68.276  65.194 1.00 71.87  ? 209 LEU A N   1 
ATOM   1576  C CA  . LEU A 1 201 ? -18.002 67.452  64.943 1.00 80.95  ? 209 LEU A CA  1 
ATOM   1577  C C   . LEU A 1 201 ? -17.759 66.054  65.490 1.00 71.31  ? 209 LEU A C   1 
ATOM   1578  O O   . LEU A 1 201 ? -16.692 65.501  65.206 1.00 113.72 ? 209 LEU A O   1 
ATOM   1579  C CB  . LEU A 1 201 ? -18.288 67.372  63.444 1.00 67.22  ? 209 LEU A CB  1 
ATOM   1580  C CG  . LEU A 1 201 ? -18.587 68.721  62.800 1.00 61.10  ? 209 LEU A CG  1 
ATOM   1581  C CD1 . LEU A 1 201 ? -19.011 68.456  61.364 1.00 66.28  ? 209 LEU A CD1 1 
ATOM   1582  C CD2 . LEU A 1 201 ? -19.656 69.585  63.494 1.00 45.69  ? 209 LEU A CD2 1 
ATOM   1583  N N   . GLU A 1 202 ? -18.789 65.446  66.096 1.00 50.15  ? 210 GLU A N   1 
ATOM   1584  C CA  . GLU A 1 202 ? -18.787 63.992  66.237 1.00 64.89  ? 210 GLU A CA  1 
ATOM   1585  C C   . GLU A 1 202 ? -18.958 63.324  64.873 1.00 58.71  ? 210 GLU A C   1 
ATOM   1586  O O   . GLU A 1 202 ? -19.972 62.698  64.638 1.00 60.13  ? 210 GLU A O   1 
ATOM   1587  C CB  . GLU A 1 202 ? -19.765 63.427  67.277 1.00 72.33  ? 210 GLU A CB  1 
ATOM   1588  C CG  . GLU A 1 202 ? -19.265 63.382  68.719 1.00 81.98  ? 210 GLU A CG  1 
ATOM   1589  C CD  . GLU A 1 202 ? -20.502 63.552  69.584 1.00 108.13 ? 210 GLU A CD  1 
ATOM   1590  O OE1 . GLU A 1 202 ? -21.442 62.676  69.703 1.00 100.23 ? 210 GLU A OE1 1 
ATOM   1591  O OE2 . GLU A 1 202 ? -20.472 64.689  70.116 1.00 90.27  ? 210 GLU A OE2 1 
ATOM   1592  N N   . TYR A 1 203 ? -17.945 63.370  63.997 1.00 69.26  ? 211 TYR A N   1 
ATOM   1593  C CA  . TYR A 1 203 ? -17.851 62.504  62.809 1.00 81.21  ? 211 TYR A CA  1 
ATOM   1594  C C   . TYR A 1 203 ? -18.204 61.041  63.168 1.00 81.02  ? 211 TYR A C   1 
ATOM   1595  O O   . TYR A 1 203 ? -19.052 60.392  62.546 1.00 58.76  ? 211 TYR A O   1 
ATOM   1596  C CB  . TYR A 1 203 ? -16.487 62.610  62.095 1.00 58.22  ? 211 TYR A CB  1 
ATOM   1597  C CG  . TYR A 1 203 ? -16.073 64.031  61.739 1.00 58.78  ? 211 TYR A CG  1 
ATOM   1598  C CD1 . TYR A 1 203 ? -16.728 64.694  60.712 1.00 80.36  ? 211 TYR A CD1 1 
ATOM   1599  C CD2 . TYR A 1 203 ? -15.027 64.696  62.358 1.00 72.11  ? 211 TYR A CD2 1 
ATOM   1600  C CE1 . TYR A 1 203 ? -16.398 65.982  60.321 1.00 68.89  ? 211 TYR A CE1 1 
ATOM   1601  C CE2 . TYR A 1 203 ? -14.705 66.002  62.000 1.00 86.47  ? 211 TYR A CE2 1 
ATOM   1602  C CZ  . TYR A 1 203 ? -15.377 66.641  60.969 1.00 68.90  ? 211 TYR A CZ  1 
ATOM   1603  O OH  . TYR A 1 203 ? -15.071 67.908  60.566 1.00 62.13  ? 211 TYR A OH  1 
ATOM   1604  N N   . ALA A 1 204 ? -17.482 60.517  64.169 1.00 86.75  ? 212 ALA A N   1 
ATOM   1605  C CA  . ALA A 1 204 ? -17.744 59.317  64.933 1.00 75.32  ? 212 ALA A CA  1 
ATOM   1606  C C   . ALA A 1 204 ? -19.244 58.900  64.887 1.00 70.01  ? 212 ALA A C   1 
ATOM   1607  O O   . ALA A 1 204 ? -19.674 57.866  64.290 1.00 60.43  ? 212 ALA A O   1 
ATOM   1608  C CB  . ALA A 1 204 ? -17.310 59.820  66.309 1.00 74.67  ? 212 ALA A CB  1 
ATOM   1609  N N   . ARG A 1 205 ? -20.053 59.728  65.571 1.00 66.11  ? 213 ARG A N   1 
ATOM   1610  C CA  . ARG A 1 205 ? -21.481 59.488  65.762 1.00 70.43  ? 213 ARG A CA  1 
ATOM   1611  C C   . ARG A 1 205 ? -22.213 59.636  64.433 1.00 78.43  ? 213 ARG A C   1 
ATOM   1612  O O   . ARG A 1 205 ? -23.094 58.838  64.097 1.00 70.96  ? 213 ARG A O   1 
ATOM   1613  C CB  . ARG A 1 205 ? -22.170 60.460  66.725 1.00 69.61  ? 213 ARG A CB  1 
ATOM   1614  C CG  . ARG A 1 205 ? -23.551 59.968  67.147 1.00 74.70  ? 213 ARG A CG  1 
ATOM   1615  C CD  . ARG A 1 205 ? -23.974 60.467  68.558 1.00 112.53 ? 213 ARG A CD  1 
ATOM   1616  N NE  . ARG A 1 205 ? -25.422 60.503  68.832 1.00 96.49  ? 213 ARG A NE  1 
ATOM   1617  C CZ  . ARG A 1 205 ? -26.363 59.743  68.210 1.00 96.03  ? 213 ARG A CZ  1 
ATOM   1618  N NH1 . ARG A 1 205 ? -26.006 58.784  67.306 1.00 63.01  ? 213 ARG A NH1 1 
ATOM   1619  N NH2 . ARG A 1 205 ? -27.648 59.961  68.548 1.00 54.81  ? 213 ARG A NH2 1 
ATOM   1620  N N   . LEU A 1 206 ? -21.834 60.671  63.677 1.00 71.77  ? 214 LEU A N   1 
ATOM   1621  C CA  . LEU A 1 206 ? -22.466 60.905  62.388 1.00 75.67  ? 214 LEU A CA  1 
ATOM   1622  C C   . LEU A 1 206 ? -22.305 59.684  61.508 1.00 86.44  ? 214 LEU A C   1 
ATOM   1623  O O   . LEU A 1 206 ? -23.201 59.375  60.748 1.00 92.28  ? 214 LEU A O   1 
ATOM   1624  C CB  . LEU A 1 206 ? -21.895 62.111  61.652 1.00 61.01  ? 214 LEU A CB  1 
ATOM   1625  C CG  . LEU A 1 206 ? -22.153 63.436  62.356 1.00 68.75  ? 214 LEU A CG  1 
ATOM   1626  C CD1 . LEU A 1 206 ? -21.483 64.459  61.456 1.00 75.87  ? 214 LEU A CD1 1 
ATOM   1627  C CD2 . LEU A 1 206 ? -23.631 63.693  62.663 1.00 49.96  ? 214 LEU A CD2 1 
ATOM   1628  N N   . ARG A 1 207 ? -21.166 59.002  61.617 1.00 94.29  ? 215 ARG A N   1 
ATOM   1629  C CA  . ARG A 1 207 ? -20.963 57.868  60.745 1.00 76.50  ? 215 ARG A CA  1 
ATOM   1630  C C   . ARG A 1 207 ? -21.917 56.730  61.125 1.00 87.81  ? 215 ARG A C   1 
ATOM   1631  O O   . ARG A 1 207 ? -22.487 56.112  60.187 1.00 62.72  ? 215 ARG A O   1 
ATOM   1632  C CB  . ARG A 1 207 ? -19.521 57.396  60.675 1.00 57.64  ? 215 ARG A CB  1 
ATOM   1633  C CG  . ARG A 1 207 ? -19.649 56.635  59.354 1.00 58.04  ? 215 ARG A CG  1 
ATOM   1634  C CD  . ARG A 1 207 ? -18.279 56.044  59.169 1.00 75.58  ? 215 ARG A CD  1 
ATOM   1635  N NE  . ARG A 1 207 ? -18.076 54.808  58.400 1.00 69.18  ? 215 ARG A NE  1 
ATOM   1636  C CZ  . ARG A 1 207 ? -17.517 54.941  57.213 1.00 118.37 ? 215 ARG A CZ  1 
ATOM   1637  N NH1 . ARG A 1 207 ? -17.924 55.934  56.437 1.00 140.87 ? 215 ARG A NH1 1 
ATOM   1638  N NH2 . ARG A 1 207 ? -16.643 54.051  56.751 1.00 142.92 ? 215 ARG A NH2 1 
ATOM   1639  N N   . LYS A 1 208 ? -22.103 56.500  62.456 1.00 61.38  ? 216 LYS A N   1 
ATOM   1640  C CA  . LYS A 1 208 ? -23.136 55.540  62.898 1.00 51.31  ? 216 LYS A CA  1 
ATOM   1641  C C   . LYS A 1 208 ? -24.474 55.925  62.231 1.00 69.82  ? 216 LYS A C   1 
ATOM   1642  O O   . LYS A 1 208 ? -25.109 55.138  61.525 1.00 53.51  ? 216 LYS A O   1 
ATOM   1643  C CB  . LYS A 1 208 ? -23.465 55.237  64.378 1.00 26.89  ? 216 LYS A CB  1 
ATOM   1644  C CG  . LYS A 1 208 ? -22.480 55.363  65.596 1.00 24.85  ? 216 LYS A CG  1 
ATOM   1645  C CD  . LYS A 1 208 ? -22.608 54.535  66.905 1.00 27.71  ? 216 LYS A CD  1 
ATOM   1646  C CE  . LYS A 1 208 ? -22.030 54.805  68.373 1.00 36.39  ? 216 LYS A CE  1 
ATOM   1647  N NZ  . LYS A 1 208 ? -22.413 55.847  69.398 1.00 27.76  ? 216 LYS A NZ  1 
ATOM   1648  N N   . ILE A 1 209 ? -24.854 57.208  62.368 1.00 71.54  ? 217 ILE A N   1 
ATOM   1649  C CA  . ILE A 1 209 ? -26.130 57.685  61.850 1.00 83.53  ? 217 ILE A CA  1 
ATOM   1650  C C   . ILE A 1 209 ? -26.220 57.484  60.347 1.00 78.10  ? 217 ILE A C   1 
ATOM   1651  O O   . ILE A 1 209 ? -27.297 57.117  59.881 1.00 70.26  ? 217 ILE A O   1 
ATOM   1652  C CB  . ILE A 1 209 ? -26.391 59.165  62.168 1.00 93.84  ? 217 ILE A CB  1 
ATOM   1653  C CG1 . ILE A 1 209 ? -26.285 59.399  63.655 1.00 95.54  ? 217 ILE A CG1 1 
ATOM   1654  C CG2 . ILE A 1 209 ? -27.771 59.610  61.677 1.00 95.06  ? 217 ILE A CG2 1 
ATOM   1655  C CD1 . ILE A 1 209 ? -26.597 60.817  64.042 1.00 98.40  ? 217 ILE A CD1 1 
ATOM   1656  N N   . ALA A 1 210 ? -25.138 57.810  59.620 1.00 60.75  ? 218 ALA A N   1 
ATOM   1657  C CA  . ALA A 1 210 ? -25.152 57.671  58.178 1.00 69.19  ? 218 ALA A CA  1 
ATOM   1658  C C   . ALA A 1 210 ? -25.298 56.192  57.835 1.00 78.57  ? 218 ALA A C   1 
ATOM   1659  O O   . ALA A 1 210 ? -26.231 55.809  57.123 1.00 60.36  ? 218 ALA A O   1 
ATOM   1660  C CB  . ALA A 1 210 ? -23.920 58.297  57.555 1.00 70.19  ? 218 ALA A CB  1 
ATOM   1661  N N   . ASP A 1 211 ? -24.420 55.362  58.434 1.00 73.14  ? 219 ASP A N   1 
ATOM   1662  C CA  . ASP A 1 211 ? -24.400 53.938  58.138 1.00 79.23  ? 219 ASP A CA  1 
ATOM   1663  C C   . ASP A 1 211 ? -25.773 53.371  58.470 1.00 75.46  ? 219 ASP A C   1 
ATOM   1664  O O   . ASP A 1 211 ? -26.311 52.558  57.747 1.00 74.67  ? 219 ASP A O   1 
ATOM   1665  C CB  . ASP A 1 211 ? -23.235 53.249  58.832 1.00 67.88  ? 219 ASP A CB  1 
ATOM   1666  C CG  . ASP A 1 211 ? -21.868 53.569  58.212 1.00 89.18  ? 219 ASP A CG  1 
ATOM   1667  O OD1 . ASP A 1 211 ? -21.774 53.867  57.024 1.00 122.27 ? 219 ASP A OD1 1 
ATOM   1668  O OD2 . ASP A 1 211 ? -20.850 53.615  58.902 1.00 59.46  ? 219 ASP A OD2 1 
ATOM   1669  N N   . GLU A 1 212 ? -26.355 53.858  59.560 1.00 68.69  ? 220 GLU A N   1 
ATOM   1670  C CA  . GLU A 1 212 ? -27.646 53.379  60.025 1.00 80.11  ? 220 GLU A CA  1 
ATOM   1671  C C   . GLU A 1 212 ? -28.687 53.549  58.922 1.00 75.22  ? 220 GLU A C   1 
ATOM   1672  O O   . GLU A 1 212 ? -29.617 52.757  58.868 1.00 95.93  ? 220 GLU A O   1 
ATOM   1673  C CB  . GLU A 1 212 ? -28.121 54.013  61.339 1.00 71.66  ? 220 GLU A CB  1 
ATOM   1674  C CG  . GLU A 1 212 ? -29.589 53.670  61.579 1.00 66.72  ? 220 GLU A CG  1 
ATOM   1675  C CD  . GLU A 1 212 ? -30.309 54.521  62.595 1.00 105.03 ? 220 GLU A CD  1 
ATOM   1676  O OE1 . GLU A 1 212 ? -30.175 55.790  62.711 1.00 101.79 ? 220 GLU A OE1 1 
ATOM   1677  O OE2 . GLU A 1 212 ? -31.128 53.828  63.247 1.00 99.64  ? 220 GLU A OE2 1 
ATOM   1678  N N   . ASN A 1 213 ? -28.559 54.610  58.108 1.00 73.61  ? 221 ASN A N   1 
ATOM   1679  C CA  . ASN A 1 213 ? -29.575 54.984  57.138 1.00 66.61  ? 221 ASN A CA  1 
ATOM   1680  C C   . ASN A 1 213 ? -29.089 54.704  55.732 1.00 76.04  ? 221 ASN A C   1 
ATOM   1681  O O   . ASN A 1 213 ? -29.813 55.029  54.792 1.00 81.35  ? 221 ASN A O   1 
ATOM   1682  C CB  . ASN A 1 213 ? -29.924 56.458  57.227 1.00 60.63  ? 221 ASN A CB  1 
ATOM   1683  C CG  . ASN A 1 213 ? -30.713 56.734  58.480 1.00 81.12  ? 221 ASN A CG  1 
ATOM   1684  O OD1 . ASN A 1 213 ? -31.939 56.539  58.502 1.00 85.75  ? 221 ASN A OD1 1 
ATOM   1685  N ND2 . ASN A 1 213 ? -30.040 57.202  59.528 1.00 90.28  ? 221 ASN A ND2 1 
ATOM   1686  N N   . GLY A 1 214 ? -27.882 54.116  55.623 1.00 77.17  ? 222 GLY A N   1 
ATOM   1687  C CA  . GLY A 1 214 ? -27.295 53.731  54.350 1.00 69.16  ? 222 GLY A CA  1 
ATOM   1688  C C   . GLY A 1 214 ? -26.902 54.985  53.594 1.00 73.44  ? 222 GLY A C   1 
ATOM   1689  O O   . GLY A 1 214 ? -26.874 54.991  52.367 1.00 98.64  ? 222 GLY A O   1 
ATOM   1690  N N   . ALA A 1 215 ? -26.596 56.057  54.335 1.00 68.69  ? 223 ALA A N   1 
ATOM   1691  C CA  . ALA A 1 215 ? -26.232 57.301  53.660 1.00 65.48  ? 223 ALA A CA  1 
ATOM   1692  C C   . ALA A 1 215 ? -24.735 57.466  53.646 1.00 72.06  ? 223 ALA A C   1 
ATOM   1693  O O   . ALA A 1 215 ? -24.037 56.832  54.417 1.00 75.33  ? 223 ALA A O   1 
ATOM   1694  C CB  . ALA A 1 215 ? -26.852 58.527  54.277 1.00 77.04  ? 223 ALA A CB  1 
ATOM   1695  N N   . TYR A 1 216 ? -24.286 58.335  52.737 1.00 79.74  ? 224 TYR A N   1 
ATOM   1696  C CA  . TYR A 1 216 ? -22.889 58.728  52.626 1.00 78.55  ? 224 TYR A CA  1 
ATOM   1697  C C   . TYR A 1 216 ? -22.615 59.802  53.660 1.00 75.38  ? 224 TYR A C   1 
ATOM   1698  O O   . TYR A 1 216 ? -23.511 60.600  53.934 1.00 125.06 ? 224 TYR A O   1 
ATOM   1699  C CB  . TYR A 1 216 ? -22.796 59.472  51.288 1.00 68.27  ? 224 TYR A CB  1 
ATOM   1700  C CG  . TYR A 1 216 ? -22.555 58.556  50.106 1.00 72.29  ? 224 TYR A CG  1 
ATOM   1701  C CD1 . TYR A 1 216 ? -21.391 57.798  50.023 1.00 79.57  ? 224 TYR A CD1 1 
ATOM   1702  C CD2 . TYR A 1 216 ? -23.452 58.486  49.057 1.00 70.14  ? 224 TYR A CD2 1 
ATOM   1703  C CE1 . TYR A 1 216 ? -21.154 56.965  48.945 1.00 59.56  ? 224 TYR A CE1 1 
ATOM   1704  C CE2 . TYR A 1 216 ? -23.226 57.646  47.977 1.00 79.24  ? 224 TYR A CE2 1 
ATOM   1705  C CZ  . TYR A 1 216 ? -22.096 56.860  47.937 1.00 63.24  ? 224 TYR A CZ  1 
ATOM   1706  O OH  . TYR A 1 216 ? -22.018 56.066  46.829 1.00 56.82  ? 224 TYR A OH  1 
ATOM   1707  N N   . LEU A 1 217 ? -21.381 59.842  54.176 1.00 66.40  ? 225 LEU A N   1 
ATOM   1708  C CA  . LEU A 1 217 ? -21.052 60.874  55.152 1.00 81.90  ? 225 LEU A CA  1 
ATOM   1709  C C   . LEU A 1 217 ? -20.037 61.807  54.534 1.00 81.71  ? 225 LEU A C   1 
ATOM   1710  O O   . LEU A 1 217 ? -18.908 61.424  54.307 1.00 95.10  ? 225 LEU A O   1 
ATOM   1711  C CB  . LEU A 1 217 ? -20.513 60.328  56.466 1.00 89.09  ? 225 LEU A CB  1 
ATOM   1712  C CG  . LEU A 1 217 ? -20.297 61.373  57.548 1.00 78.93  ? 225 LEU A CG  1 
ATOM   1713  C CD1 . LEU A 1 217 ? -21.696 61.693  57.975 1.00 58.14  ? 225 LEU A CD1 1 
ATOM   1714  C CD2 . LEU A 1 217 ? -19.451 60.724  58.687 1.00 81.15  ? 225 LEU A CD2 1 
ATOM   1715  N N   . MET A 1 218 ? -20.493 62.980  54.127 1.00 84.82  ? 226 MET A N   1 
ATOM   1716  C CA  . MET A 1 218 ? -19.656 63.900  53.376 1.00 76.86  ? 226 MET A CA  1 
ATOM   1717  C C   . MET A 1 218 ? -19.283 65.032  54.318 1.00 77.20  ? 226 MET A C   1 
ATOM   1718  O O   . MET A 1 218 ? -20.153 65.703  54.892 1.00 69.23  ? 226 MET A O   1 
ATOM   1719  C CB  . MET A 1 218 ? -20.373 64.538  52.175 1.00 67.13  ? 226 MET A CB  1 
ATOM   1720  C CG  . MET A 1 218 ? -19.512 65.598  51.519 1.00 68.43  ? 226 MET A CG  1 
ATOM   1721  S SD  . MET A 1 218 ? -20.489 66.644  50.430 1.00 78.37  ? 226 MET A SD  1 
ATOM   1722  C CE  . MET A 1 218 ? -20.581 68.224  51.292 1.00 103.16 ? 226 MET A CE  1 
ATOM   1723  N N   . ALA A 1 219 ? -17.971 65.238  54.466 1.00 67.73  ? 227 ALA A N   1 
ATOM   1724  C CA  . ALA A 1 219 ? -17.518 66.288  55.353 1.00 59.30  ? 227 ALA A CA  1 
ATOM   1725  C C   . ALA A 1 219 ? -17.172 67.494  54.499 1.00 72.18  ? 227 ALA A C   1 
ATOM   1726  O O   . ALA A 1 219 ? -16.585 67.324  53.415 1.00 59.08  ? 227 ALA A O   1 
ATOM   1727  C CB  . ALA A 1 219 ? -16.311 65.802  56.072 1.00 56.14  ? 227 ALA A CB  1 
ATOM   1728  N N   . ASP A 1 220 ? -17.586 68.685  54.973 1.00 67.03  ? 228 ASP A N   1 
ATOM   1729  C CA  . ASP A 1 220 ? -17.209 69.934  54.315 1.00 67.39  ? 228 ASP A CA  1 
ATOM   1730  C C   . ASP A 1 220 ? -16.279 70.658  55.278 1.00 65.68  ? 228 ASP A C   1 
ATOM   1731  O O   . ASP A 1 220 ? -16.725 71.307  56.229 1.00 80.49  ? 228 ASP A O   1 
ATOM   1732  C CB  . ASP A 1 220 ? -18.409 70.743  53.831 1.00 68.81  ? 228 ASP A CB  1 
ATOM   1733  C CG  . ASP A 1 220 ? -18.121 72.026  53.063 1.00 77.43  ? 228 ASP A CG  1 
ATOM   1734  O OD1 . ASP A 1 220 ? -16.967 72.479  53.020 1.00 106.01 ? 228 ASP A OD1 1 
ATOM   1735  O OD2 . ASP A 1 220 ? -19.041 72.539  52.436 1.00 77.43  ? 228 ASP A OD2 1 
ATOM   1736  N N   . MET A 1 221 ? -14.973 70.510  55.029 1.00 64.74  ? 229 MET A N   1 
ATOM   1737  C CA  . MET A 1 221 ? -13.971 70.996  55.969 1.00 78.36  ? 229 MET A CA  1 
ATOM   1738  C C   . MET A 1 221 ? -13.474 72.367  55.526 1.00 83.20  ? 229 MET A C   1 
ATOM   1739  O O   . MET A 1 221 ? -12.414 72.778  55.987 1.00 89.08  ? 229 MET A O   1 
ATOM   1740  C CB  . MET A 1 221 ? -12.776 70.030  56.095 1.00 82.12  ? 229 MET A CB  1 
ATOM   1741  C CG  . MET A 1 221 ? -11.961 69.873  54.800 1.00 97.52  ? 229 MET A CG  1 
ATOM   1742  S SD  . MET A 1 221 ? -10.405 68.957  54.706 1.00 87.41  ? 229 MET A SD  1 
ATOM   1743  C CE  . MET A 1 221 ? -9.698  69.880  56.084 1.00 143.90 ? 229 MET A CE  1 
ATOM   1744  N N   . ALA A 1 222 ? -14.237 73.070  54.673 1.00 85.41  ? 230 ALA A N   1 
ATOM   1745  C CA  . ALA A 1 222 ? -13.860 74.352  54.084 1.00 82.32  ? 230 ALA A CA  1 
ATOM   1746  C C   . ALA A 1 222 ? -13.219 75.258  55.120 1.00 82.20  ? 230 ALA A C   1 
ATOM   1747  O O   . ALA A 1 222 ? -12.120 75.781  54.858 1.00 65.64  ? 230 ALA A O   1 
ATOM   1748  C CB  . ALA A 1 222 ? -15.062 75.052  53.469 1.00 81.11  ? 230 ALA A CB  1 
ATOM   1749  N N   . HIS A 1 223 ? -13.954 75.437  56.246 1.00 76.74  ? 231 HIS A N   1 
ATOM   1750  C CA  . HIS A 1 223 ? -13.591 76.378  57.292 1.00 73.53  ? 231 HIS A CA  1 
ATOM   1751  C C   . HIS A 1 223 ? -12.356 75.937  58.070 1.00 67.55  ? 231 HIS A C   1 
ATOM   1752  O O   . HIS A 1 223 ? -11.633 76.790  58.565 1.00 83.76  ? 231 HIS A O   1 
ATOM   1753  C CB  . HIS A 1 223 ? -14.754 76.611  58.265 1.00 79.89  ? 231 HIS A CB  1 
ATOM   1754  C CG  . HIS A 1 223 ? -15.348 77.954  58.149 1.00 91.01  ? 231 HIS A CG  1 
ATOM   1755  N ND1 . HIS A 1 223 ? -16.390 78.244  57.305 1.00 107.37 ? 231 HIS A ND1 1 
ATOM   1756  C CD2 . HIS A 1 223 ? -15.001 79.093  58.748 1.00 95.18  ? 231 HIS A CD2 1 
ATOM   1757  C CE1 . HIS A 1 223 ? -16.668 79.540  57.383 1.00 108.24 ? 231 HIS A CE1 1 
ATOM   1758  N NE2 . HIS A 1 223 ? -15.825 80.079  58.259 1.00 127.27 ? 231 HIS A NE2 1 
ATOM   1759  N N   . ILE A 1 224 ? -12.124 74.619  58.185 1.00 55.41  ? 232 ILE A N   1 
ATOM   1760  C CA  . ILE A 1 224 ? -11.146 74.094  59.118 1.00 60.64  ? 232 ILE A CA  1 
ATOM   1761  C C   . ILE A 1 224 ? -10.114 73.266  58.351 1.00 85.53  ? 232 ILE A C   1 
ATOM   1762  O O   . ILE A 1 224 ? -9.375  72.479  58.959 1.00 86.56  ? 232 ILE A O   1 
ATOM   1763  C CB  . ILE A 1 224 ? -11.853 73.260  60.206 1.00 46.92  ? 232 ILE A CB  1 
ATOM   1764  C CG1 . ILE A 1 224 ? -12.338 71.895  59.665 1.00 30.76  ? 232 ILE A CG1 1 
ATOM   1765  C CG2 . ILE A 1 224 ? -12.950 74.066  60.963 1.00 33.28  ? 232 ILE A CG2 1 
ATOM   1766  C CD1 . ILE A 1 224 ? -12.802 70.981  60.816 1.00 25.06  ? 232 ILE A CD1 1 
ATOM   1767  N N   . SER A 1 225 ? -10.038 73.470  57.028 1.00 90.35  ? 233 SER A N   1 
ATOM   1768  C CA  . SER A 1 225 ? -9.128  72.692  56.185 1.00 96.05  ? 233 SER A CA  1 
ATOM   1769  C C   . SER A 1 225 ? -7.715  72.792  56.718 1.00 114.32 ? 233 SER A C   1 
ATOM   1770  O O   . SER A 1 225 ? -7.024  71.791  56.849 1.00 150.26 ? 233 SER A O   1 
ATOM   1771  C CB  . SER A 1 225 ? -9.189  73.015  54.724 1.00 85.60  ? 233 SER A CB  1 
ATOM   1772  O OG  . SER A 1 225 ? -9.275  74.413  54.498 1.00 113.82 ? 233 SER A OG  1 
ATOM   1773  N N   . GLY A 1 226 ? -7.286  74.014  57.011 1.00 113.60 ? 234 GLY A N   1 
ATOM   1774  C CA  . GLY A 1 226 ? -5.960  74.234  57.567 1.00 118.87 ? 234 GLY A CA  1 
ATOM   1775  C C   . GLY A 1 226 ? -5.808  73.617  58.953 1.00 118.04 ? 234 GLY A C   1 
ATOM   1776  O O   . GLY A 1 226 ? -4.744  73.110  59.296 1.00 132.51 ? 234 GLY A O   1 
ATOM   1777  N N   . LEU A 1 227 ? -6.857  73.710  59.770 1.00 112.69 ? 235 LEU A N   1 
ATOM   1778  C CA  . LEU A 1 227 ? -6.800  73.191  61.125 1.00 123.01 ? 235 LEU A CA  1 
ATOM   1779  C C   . LEU A 1 227 ? -6.561  71.691  61.047 1.00 113.41 ? 235 LEU A C   1 
ATOM   1780  O O   . LEU A 1 227 ? -5.739  71.153  61.774 1.00 117.20 ? 235 LEU A O   1 
ATOM   1781  C CB  . LEU A 1 227 ? -8.071  73.515  61.908 1.00 134.40 ? 235 LEU A CB  1 
ATOM   1782  C CG  . LEU A 1 227 ? -8.396  75.005  62.091 1.00 115.11 ? 235 LEU A CG  1 
ATOM   1783  C CD1 . LEU A 1 227 ? -9.508  75.152  63.119 1.00 153.10 ? 235 LEU A CD1 1 
ATOM   1784  C CD2 . LEU A 1 227 ? -7.213  75.835  62.519 1.00 85.75  ? 235 LEU A CD2 1 
ATOM   1785  N N   . VAL A 1 228 ? -7.261  71.047  60.114 1.00 100.98 ? 236 VAL A N   1 
ATOM   1786  C CA  . VAL A 1 228 ? -7.208  69.600  59.995 1.00 107.47 ? 236 VAL A CA  1 
ATOM   1787  C C   . VAL A 1 228 ? -5.829  69.172  59.507 1.00 92.26  ? 236 VAL A C   1 
ATOM   1788  O O   . VAL A 1 228 ? -5.240  68.276  60.086 1.00 89.12  ? 236 VAL A O   1 
ATOM   1789  C CB  . VAL A 1 228 ? -8.360  69.086  59.117 1.00 79.25  ? 236 VAL A CB  1 
ATOM   1790  C CG1 . VAL A 1 228 ? -8.143  67.678  58.649 1.00 56.32  ? 236 VAL A CG1 1 
ATOM   1791  C CG2 . VAL A 1 228 ? -9.651  69.138  59.902 1.00 75.86  ? 236 VAL A CG2 1 
ATOM   1792  N N   . ALA A 1 229 ? -5.299  69.862  58.498 1.00 88.21  ? 237 ALA A N   1 
ATOM   1793  C CA  . ALA A 1 229 ? -3.943  69.661  57.986 1.00 87.95  ? 237 ALA A CA  1 
ATOM   1794  C C   . ALA A 1 229 ? -2.908  69.609  59.103 1.00 65.51  ? 237 ALA A C   1 
ATOM   1795  O O   . ALA A 1 229 ? -2.063  68.722  59.118 1.00 111.73 ? 237 ALA A O   1 
ATOM   1796  C CB  . ALA A 1 229 ? -3.588  70.738  56.957 1.00 62.86  ? 237 ALA A CB  1 
ATOM   1797  N N   . ALA A 1 230 ? -2.973  70.555  60.043 1.00 70.37  ? 238 ALA A N   1 
ATOM   1798  C CA  . ALA A 1 230 ? -1.986  70.647  61.113 1.00 68.66  ? 238 ALA A CA  1 
ATOM   1799  C C   . ALA A 1 230 ? -2.367  69.752  62.285 1.00 63.00  ? 238 ALA A C   1 
ATOM   1800  O O   . ALA A 1 230 ? -1.630  69.674  63.255 1.00 81.14  ? 238 ALA A O   1 
ATOM   1801  C CB  . ALA A 1 230 ? -1.779  72.089  61.543 1.00 76.14  ? 238 ALA A CB  1 
ATOM   1802  N N   . GLY A 1 231 ? -3.529  69.096  62.199 1.00 66.38  ? 239 GLY A N   1 
ATOM   1803  C CA  . GLY A 1 231 ? -4.006  68.145  63.195 1.00 57.35  ? 239 GLY A CA  1 
ATOM   1804  C C   . GLY A 1 231 ? -4.432  68.865  64.472 1.00 71.31  ? 239 GLY A C   1 
ATOM   1805  O O   . GLY A 1 231 ? -4.701  68.197  65.466 1.00 70.42  ? 239 GLY A O   1 
ATOM   1806  N N   . VAL A 1 232 ? -4.596  70.203  64.409 1.00 67.91  ? 240 VAL A N   1 
ATOM   1807  C CA  . VAL A 1 232 ? -4.993  71.043  65.530 1.00 62.81  ? 240 VAL A CA  1 
ATOM   1808  C C   . VAL A 1 232 ? -6.442  70.677  65.876 1.00 64.19  ? 240 VAL A C   1 
ATOM   1809  O O   . VAL A 1 232 ? -6.995  71.151  66.831 1.00 78.43  ? 240 VAL A O   1 
ATOM   1810  C CB  . VAL A 1 232 ? -4.847  72.478  64.953 1.00 82.16  ? 240 VAL A CB  1 
ATOM   1811  C CG1 . VAL A 1 232 ? -5.053  73.620  65.942 1.00 66.04  ? 240 VAL A CG1 1 
ATOM   1812  C CG2 . VAL A 1 232 ? -3.488  72.742  64.309 1.00 94.05  ? 240 VAL A CG2 1 
ATOM   1813  N N   . VAL A 1 233 ? -7.079  69.814  65.089 1.00 90.48  ? 241 VAL A N   1 
ATOM   1814  C CA  . VAL A 1 233 ? -8.470  69.437  65.258 1.00 84.10  ? 241 VAL A CA  1 
ATOM   1815  C C   . VAL A 1 233 ? -8.630  68.025  64.708 1.00 105.17 ? 241 VAL A C   1 
ATOM   1816  O O   . VAL A 1 233 ? -7.988  67.696  63.686 1.00 130.26 ? 241 VAL A O   1 
ATOM   1817  C CB  . VAL A 1 233 ? -9.325  70.333  64.353 1.00 85.14  ? 241 VAL A CB  1 
ATOM   1818  C CG1 . VAL A 1 233 ? -10.736 69.770  64.256 1.00 85.81  ? 241 VAL A CG1 1 
ATOM   1819  C CG2 . VAL A 1 233 ? -9.258  71.820  64.689 1.00 70.45  ? 241 VAL A CG2 1 
ATOM   1820  N N   . PRO A 1 234 ? -9.482  67.172  65.343 1.00 88.66  ? 242 PRO A N   1 
ATOM   1821  C CA  . PRO A 1 234 ? -9.775  65.815  64.865 1.00 69.46  ? 242 PRO A CA  1 
ATOM   1822  C C   . PRO A 1 234 ? -10.139 65.846  63.391 1.00 61.74  ? 242 PRO A C   1 
ATOM   1823  O O   . PRO A 1 234 ? -10.906 66.731  62.963 1.00 93.22  ? 242 PRO A O   1 
ATOM   1824  C CB  . PRO A 1 234 ? -10.967 65.347  65.711 1.00 76.52  ? 242 PRO A CB  1 
ATOM   1825  C CG  . PRO A 1 234 ? -10.806 66.158  66.978 1.00 91.59  ? 242 PRO A CG  1 
ATOM   1826  C CD  . PRO A 1 234 ? -10.216 67.503  66.570 1.00 109.55 ? 242 PRO A CD  1 
ATOM   1827  N N   . SER A 1 235 ? -9.597  64.875  62.635 1.00 43.01  ? 243 SER A N   1 
ATOM   1828  C CA  . SER A 1 235 ? -9.799  64.886  61.183 1.00 55.18  ? 243 SER A CA  1 
ATOM   1829  C C   . SER A 1 235 ? -11.079 64.156  60.721 1.00 78.44  ? 243 SER A C   1 
ATOM   1830  O O   . SER A 1 235 ? -11.480 63.086  61.224 1.00 76.96  ? 243 SER A O   1 
ATOM   1831  C CB  . SER A 1 235 ? -8.590  64.344  60.508 1.00 61.34  ? 243 SER A CB  1 
ATOM   1832  O OG  . SER A 1 235 ? -8.878  64.072  59.144 1.00 50.14  ? 243 SER A OG  1 
ATOM   1833  N N   . PRO A 1 236 ? -11.825 64.724  59.747 1.00 90.16  ? 244 PRO A N   1 
ATOM   1834  C CA  . PRO A 1 236 ? -13.010 64.042  59.226 1.00 81.30  ? 244 PRO A CA  1 
ATOM   1835  C C   . PRO A 1 236 ? -12.657 62.840  58.379 1.00 85.29  ? 244 PRO A C   1 
ATOM   1836  O O   . PRO A 1 236 ? -13.553 62.040  58.089 1.00 78.10  ? 244 PRO A O   1 
ATOM   1837  C CB  . PRO A 1 236 ? -13.625 65.120  58.366 1.00 67.99  ? 244 PRO A CB  1 
ATOM   1838  C CG  . PRO A 1 236 ? -12.419 65.877  57.828 1.00 90.75  ? 244 PRO A CG  1 
ATOM   1839  C CD  . PRO A 1 236 ? -11.610 66.037  59.114 1.00 83.14  ? 244 PRO A CD  1 
ATOM   1840  N N   . PHE A 1 237 ? -11.358 62.740  57.998 1.00 62.26  ? 245 PHE A N   1 
ATOM   1841  C CA  . PHE A 1 237 ? -10.946 61.710  57.064 1.00 75.58  ? 245 PHE A CA  1 
ATOM   1842  C C   . PHE A 1 237 ? -11.164 60.327  57.660 1.00 90.45  ? 245 PHE A C   1 
ATOM   1843  O O   . PHE A 1 237 ? -11.235 59.317  56.942 1.00 121.03 ? 245 PHE A O   1 
ATOM   1844  C CB  . PHE A 1 237 ? -9.528  61.895  56.549 1.00 58.55  ? 245 PHE A CB  1 
ATOM   1845  C CG  . PHE A 1 237 ? -9.469  63.004  55.526 1.00 69.33  ? 245 PHE A CG  1 
ATOM   1846  C CD1 . PHE A 1 237 ? -9.875  62.811  54.193 1.00 85.19  ? 245 PHE A CD1 1 
ATOM   1847  C CD2 . PHE A 1 237 ? -9.005  64.247  55.918 1.00 65.71  ? 245 PHE A CD2 1 
ATOM   1848  C CE1 . PHE A 1 237 ? -9.834  63.866  53.271 1.00 81.95  ? 245 PHE A CE1 1 
ATOM   1849  C CE2 . PHE A 1 237 ? -8.960  65.304  54.998 1.00 80.38  ? 245 PHE A CE2 1 
ATOM   1850  C CZ  . PHE A 1 237 ? -9.362  65.107  53.679 1.00 83.39  ? 245 PHE A CZ  1 
ATOM   1851  N N   . GLU A 1 238 ? -11.271 60.301  58.986 1.00 89.73  ? 246 GLU A N   1 
ATOM   1852  C CA  . GLU A 1 238 ? -11.215 59.019  59.643 1.00 105.11 ? 246 GLU A CA  1 
ATOM   1853  C C   . GLU A 1 238 ? -12.586 58.349  59.611 1.00 100.05 ? 246 GLU A C   1 
ATOM   1854  O O   . GLU A 1 238 ? -12.638 57.145  59.744 1.00 123.41 ? 246 GLU A O   1 
ATOM   1855  C CB  . GLU A 1 238 ? -10.496 59.248  60.965 1.00 116.57 ? 246 GLU A CB  1 
ATOM   1856  C CG  . GLU A 1 238 ? -10.457 58.047  61.894 1.00 116.42 ? 246 GLU A CG  1 
ATOM   1857  C CD  . GLU A 1 238 ? -10.330 58.458  63.349 1.00 124.41 ? 246 GLU A CD  1 
ATOM   1858  O OE1 . GLU A 1 238 ? -10.211 57.564  64.200 1.00 151.01 ? 246 GLU A OE1 1 
ATOM   1859  O OE2 . GLU A 1 238 ? -10.316 59.661  63.653 1.00 146.92 ? 246 GLU A OE2 1 
ATOM   1860  N N   . HIS A 1 239 ? -13.677 59.098  59.396 1.00 99.43  ? 247 HIS A N   1 
ATOM   1861  C CA  . HIS A 1 239 ? -15.019 58.514  59.421 1.00 92.96  ? 247 HIS A CA  1 
ATOM   1862  C C   . HIS A 1 239 ? -15.809 58.789  58.143 1.00 87.79  ? 247 HIS A C   1 
ATOM   1863  O O   . HIS A 1 239 ? -16.651 57.989  57.799 1.00 86.15  ? 247 HIS A O   1 
ATOM   1864  C CB  . HIS A 1 239 ? -15.872 59.042  60.575 1.00 91.58  ? 247 HIS A CB  1 
ATOM   1865  C CG  . HIS A 1 239 ? -15.079 59.128  61.822 1.00 101.60 ? 247 HIS A CG  1 
ATOM   1866  N ND1 . HIS A 1 239 ? -15.217 58.161  62.783 1.00 101.99 ? 247 HIS A ND1 1 
ATOM   1867  C CD2 . HIS A 1 239 ? -14.146 59.977  62.263 1.00 113.34 ? 247 HIS A CD2 1 
ATOM   1868  C CE1 . HIS A 1 239 ? -14.423 58.433  63.803 1.00 113.44 ? 247 HIS A CE1 1 
ATOM   1869  N NE2 . HIS A 1 239 ? -13.736 59.513  63.491 1.00 147.40 ? 247 HIS A NE2 1 
ATOM   1870  N N   . CYS A 1 240 ? -15.537 59.898  57.435 1.00 74.78  ? 248 CYS A N   1 
ATOM   1871  C CA  . CYS A 1 240 ? -16.345 60.306  56.284 1.00 75.67  ? 248 CYS A CA  1 
ATOM   1872  C C   . CYS A 1 240 ? -15.921 59.633  54.966 1.00 68.06  ? 248 CYS A C   1 
ATOM   1873  O O   . CYS A 1 240 ? -14.781 59.244  54.778 1.00 74.12  ? 248 CYS A O   1 
ATOM   1874  C CB  . CYS A 1 240 ? -16.247 61.814  56.152 1.00 85.14  ? 248 CYS A CB  1 
ATOM   1875  S SG  . CYS A 1 240 ? -16.853 62.614  57.668 1.00 90.51  ? 248 CYS A SG  1 
ATOM   1876  N N   . HIS A 1 241 ? -16.867 59.441  54.055 1.00 66.09  ? 249 HIS A N   1 
ATOM   1877  C CA  . HIS A 1 241 ? -16.616 58.737  52.800 1.00 84.54  ? 249 HIS A CA  1 
ATOM   1878  C C   . HIS A 1 241 ? -16.025 59.704  51.792 1.00 77.87  ? 249 HIS A C   1 
ATOM   1879  O O   . HIS A 1 241 ? -15.201 59.319  50.961 1.00 74.92  ? 249 HIS A O   1 
ATOM   1880  C CB  . HIS A 1 241 ? -17.914 58.214  52.159 1.00 92.61  ? 249 HIS A CB  1 
ATOM   1881  C CG  . HIS A 1 241 ? -18.575 57.185  53.010 1.00 83.39  ? 249 HIS A CG  1 
ATOM   1882  N ND1 . HIS A 1 241 ? -19.607 57.499  53.861 1.00 78.78  ? 249 HIS A ND1 1 
ATOM   1883  C CD2 . HIS A 1 241 ? -18.296 55.888  53.218 1.00 66.28  ? 249 HIS A CD2 1 
ATOM   1884  C CE1 . HIS A 1 241 ? -19.962 56.411  54.527 1.00 92.94  ? 249 HIS A CE1 1 
ATOM   1885  N NE2 . HIS A 1 241 ? -19.192 55.415  54.140 1.00 86.49  ? 249 HIS A NE2 1 
ATOM   1886  N N   . VAL A 1 242 ? -16.499 60.951  51.888 1.00 70.49  ? 250 VAL A N   1 
ATOM   1887  C CA  . VAL A 1 242 ? -16.008 62.026  51.046 1.00 70.21  ? 250 VAL A CA  1 
ATOM   1888  C C   . VAL A 1 242 ? -15.767 63.265  51.902 1.00 75.93  ? 250 VAL A C   1 
ATOM   1889  O O   . VAL A 1 242 ? -16.519 63.513  52.865 1.00 62.03  ? 250 VAL A O   1 
ATOM   1890  C CB  . VAL A 1 242 ? -17.065 62.280  49.976 1.00 57.19  ? 250 VAL A CB  1 
ATOM   1891  C CG1 . VAL A 1 242 ? -16.860 63.616  49.264 1.00 50.41  ? 250 VAL A CG1 1 
ATOM   1892  C CG2 . VAL A 1 242 ? -17.055 61.120  49.002 1.00 66.72  ? 250 VAL A CG2 1 
ATOM   1893  N N   . VAL A 1 243 ? -14.701 64.004  51.537 1.00 55.03  ? 251 VAL A N   1 
ATOM   1894  C CA  . VAL A 1 243 ? -14.417 65.261  52.210 1.00 62.24  ? 251 VAL A CA  1 
ATOM   1895  C C   . VAL A 1 243 ? -14.183 66.362  51.181 1.00 78.67  ? 251 VAL A C   1 
ATOM   1896  O O   . VAL A 1 243 ? -13.274 66.250  50.349 1.00 77.51  ? 251 VAL A O   1 
ATOM   1897  C CB  . VAL A 1 243 ? -13.205 65.123  53.135 1.00 49.89  ? 251 VAL A CB  1 
ATOM   1898  C CG1 . VAL A 1 243 ? -12.906 66.470  53.787 1.00 62.97  ? 251 VAL A CG1 1 
ATOM   1899  C CG2 . VAL A 1 243 ? -13.422 64.056  54.200 1.00 41.07  ? 251 VAL A CG2 1 
ATOM   1900  N N   . THR A 1 244 ? -15.008 67.431  51.253 1.00 59.14  ? 252 THR A N   1 
ATOM   1901  C CA  . THR A 1 244 ? -14.878 68.518  50.284 1.00 65.36  ? 252 THR A CA  1 
ATOM   1902  C C   . THR A 1 244 ? -14.257 69.692  51.007 1.00 57.39  ? 252 THR A C   1 
ATOM   1903  O O   . THR A 1 244 ? -14.385 69.768  52.230 1.00 66.46  ? 252 THR A O   1 
ATOM   1904  C CB  . THR A 1 244 ? -16.213 68.912  49.651 1.00 88.49  ? 252 THR A CB  1 
ATOM   1905  O OG1 . THR A 1 244 ? -17.085 69.271  50.720 1.00 86.25  ? 252 THR A OG1 1 
ATOM   1906  C CG2 . THR A 1 244 ? -16.873 67.789  48.871 1.00 103.67 ? 252 THR A CG2 1 
ATOM   1907  N N   . THR A 1 245 ? -13.610 70.588  50.257 1.00 61.97  ? 253 THR A N   1 
ATOM   1908  C CA  . THR A 1 245 ? -13.022 71.745  50.920 1.00 93.67  ? 253 THR A CA  1 
ATOM   1909  C C   . THR A 1 245 ? -12.795 72.913  49.966 1.00 77.23  ? 253 THR A C   1 
ATOM   1910  O O   . THR A 1 245 ? -12.621 72.744  48.767 1.00 80.73  ? 253 THR A O   1 
ATOM   1911  C CB  . THR A 1 245 ? -11.687 71.329  51.523 1.00 89.40  ? 253 THR A CB  1 
ATOM   1912  O OG1 . THR A 1 245 ? -11.358 72.429  52.359 1.00 104.43 ? 253 THR A OG1 1 
ATOM   1913  C CG2 . THR A 1 245 ? -10.639 71.227  50.443 1.00 82.18  ? 253 THR A CG2 1 
ATOM   1914  N N   . THR A 1 246 ? -12.732 74.090  50.565 1.00 62.13  ? 254 THR A N   1 
ATOM   1915  C CA  . THR A 1 246 ? -12.239 75.279  49.920 1.00 71.95  ? 254 THR A CA  1 
ATOM   1916  C C   . THR A 1 246 ? -10.713 75.381  50.129 1.00 87.87  ? 254 THR A C   1 
ATOM   1917  O O   . THR A 1 246 ? -10.176 75.048  51.209 1.00 85.13  ? 254 THR A O   1 
ATOM   1918  C CB  . THR A 1 246 ? -13.046 76.397  50.585 1.00 59.28  ? 254 THR A CB  1 
ATOM   1919  O OG1 . THR A 1 246 ? -12.948 77.444  49.633 1.00 63.12  ? 254 THR A OG1 1 
ATOM   1920  C CG2 . THR A 1 246 ? -12.519 76.742  51.972 1.00 46.41  ? 254 THR A CG2 1 
ATOM   1921  N N   . THR A 1 247 ? -10.032 75.940  49.114 1.00 70.75  ? 255 THR A N   1 
ATOM   1922  C CA  . THR A 1 247 ? -8.580  76.004  49.142 1.00 71.91  ? 255 THR A CA  1 
ATOM   1923  C C   . THR A 1 247 ? -8.107  77.327  49.744 1.00 72.87  ? 255 THR A C   1 
ATOM   1924  O O   . THR A 1 247 ? -6.922  77.460  50.035 1.00 71.41  ? 255 THR A O   1 
ATOM   1925  C CB  . THR A 1 247 ? -7.953  75.779  47.758 1.00 84.76  ? 255 THR A CB  1 
ATOM   1926  O OG1 . THR A 1 247 ? -8.477  76.738  46.837 1.00 93.51  ? 255 THR A OG1 1 
ATOM   1927  C CG2 . THR A 1 247 ? -8.156  74.367  47.249 1.00 81.95  ? 255 THR A CG2 1 
ATOM   1928  N N   . HIS A 1 248 ? -9.008  78.306  49.905 1.00 70.86  ? 256 HIS A N   1 
ATOM   1929  C CA  . HIS A 1 248 ? -8.713  79.446  50.780 1.00 86.35  ? 256 HIS A CA  1 
ATOM   1930  C C   . HIS A 1 248 ? -9.183  79.177  52.228 1.00 87.44  ? 256 HIS A C   1 
ATOM   1931  O O   . HIS A 1 248 ? -9.042  78.048  52.775 1.00 52.94  ? 256 HIS A O   1 
ATOM   1932  C CB  . HIS A 1 248 ? -9.314  80.722  50.195 1.00 82.51  ? 256 HIS A CB  1 
ATOM   1933  C CG  . HIS A 1 248 ? -10.723 80.584  49.690 1.00 87.96  ? 256 HIS A CG  1 
ATOM   1934  N ND1 . HIS A 1 248 ? -11.199 79.908  48.567 1.00 70.23  ? 256 HIS A ND1 1 
ATOM   1935  C CD2 . HIS A 1 248 ? -11.783 81.146  50.288 1.00 88.57  ? 256 HIS A CD2 1 
ATOM   1936  C CE1 . HIS A 1 248 ? -12.524 80.063  48.517 1.00 103.62 ? 256 HIS A CE1 1 
ATOM   1937  N NE2 . HIS A 1 248 ? -12.900 80.791  49.553 1.00 126.03 ? 256 HIS A NE2 1 
ATOM   1938  N N   . LYS A 1 249 ? -9.695  80.240  52.875 1.00 66.74  ? 257 LYS A N   1 
ATOM   1939  C CA  . LYS A 1 249 ? -9.907  80.180  54.314 1.00 106.10 ? 257 LYS A CA  1 
ATOM   1940  C C   . LYS A 1 249 ? -8.624  79.725  55.037 1.00 89.35  ? 257 LYS A C   1 
ATOM   1941  O O   . LYS A 1 249 ? -7.528  80.214  54.772 1.00 73.35  ? 257 LYS A O   1 
ATOM   1942  C CB  . LYS A 1 249 ? -11.150 79.342  54.605 1.00 102.06 ? 257 LYS A CB  1 
ATOM   1943  C CG  . LYS A 1 249 ? -12.355 79.819  53.832 1.00 85.10  ? 257 LYS A CG  1 
ATOM   1944  C CD  . LYS A 1 249 ? -13.709 79.197  54.140 1.00 97.85  ? 257 LYS A CD  1 
ATOM   1945  C CE  . LYS A 1 249 ? -14.665 79.561  53.027 1.00 114.58 ? 257 LYS A CE  1 
ATOM   1946  N NZ  . LYS A 1 249 ? -16.097 79.407  53.332 1.00 113.28 ? 257 LYS A NZ  1 
ATOM   1947  N N   . THR A 1 250 ? -8.753  78.784  55.978 1.00 72.23  ? 258 THR A N   1 
ATOM   1948  C CA  . THR A 1 250 ? -7.605  78.335  56.764 1.00 95.07  ? 258 THR A CA  1 
ATOM   1949  C C   . THR A 1 250 ? -6.530  77.593  55.951 1.00 86.60  ? 258 THR A C   1 
ATOM   1950  O O   . THR A 1 250 ? -5.473  77.254  56.477 1.00 74.70  ? 258 THR A O   1 
ATOM   1951  C CB  . THR A 1 250 ? -8.084  77.509  57.959 1.00 113.39 ? 258 THR A CB  1 
ATOM   1952  O OG1 . THR A 1 250 ? -8.987  76.494  57.502 1.00 87.32  ? 258 THR A OG1 1 
ATOM   1953  C CG2 . THR A 1 250 ? -8.698  78.385  59.035 1.00 142.74 ? 258 THR A CG2 1 
ATOM   1954  N N   . LEU A 1 251 ? -6.794  77.268  54.684 1.00 88.52  ? 259 LEU A N   1 
ATOM   1955  C CA  . LEU A 1 251 ? -5.790  76.592  53.878 1.00 82.58  ? 259 LEU A CA  1 
ATOM   1956  C C   . LEU A 1 251 ? -4.905  77.632  53.200 1.00 84.94  ? 259 LEU A C   1 
ATOM   1957  O O   . LEU A 1 251 ? -3.843  77.268  52.658 1.00 94.56  ? 259 LEU A O   1 
ATOM   1958  C CB  . LEU A 1 251 ? -6.394  75.623  52.865 1.00 66.42  ? 259 LEU A CB  1 
ATOM   1959  C CG  . LEU A 1 251 ? -5.463  74.482  52.428 1.00 66.45  ? 259 LEU A CG  1 
ATOM   1960  C CD1 . LEU A 1 251 ? -4.950  73.712  53.611 1.00 89.58  ? 259 LEU A CD1 1 
ATOM   1961  C CD2 . LEU A 1 251 ? -6.097  73.417  51.589 1.00 74.90  ? 259 LEU A CD2 1 
ATOM   1962  N N   . ARG A 1 252 ? -5.368  78.902  53.263 1.00 73.78  ? 260 ARG A N   1 
ATOM   1963  C CA  . ARG A 1 252 ? -4.597  80.093  52.893 1.00 100.35 ? 260 ARG A CA  1 
ATOM   1964  C C   . ARG A 1 252 ? -4.050  80.035  51.462 1.00 113.34 ? 260 ARG A C   1 
ATOM   1965  O O   . ARG A 1 252 ? -2.960  80.573  51.137 1.00 112.64 ? 260 ARG A O   1 
ATOM   1966  C CB  . ARG A 1 252 ? -3.368  80.316  53.793 1.00 137.25 ? 260 ARG A CB  1 
ATOM   1967  C CG  . ARG A 1 252 ? -3.466  80.908  55.196 1.00 119.20 ? 260 ARG A CG  1 
ATOM   1968  C CD  . ARG A 1 252 ? -2.408  81.993  55.290 1.00 101.41 ? 260 ARG A CD  1 
ATOM   1969  N NE  . ARG A 1 252 ? -1.075  81.390  55.225 1.00 100.60 ? 260 ARG A NE  1 
ATOM   1970  C CZ  . ARG A 1 252 ? -0.301  81.193  56.276 1.00 87.34  ? 260 ARG A CZ  1 
ATOM   1971  N NH1 . ARG A 1 252 ? -0.684  81.599  57.488 1.00 64.84  ? 260 ARG A NH1 1 
ATOM   1972  N NH2 . ARG A 1 252 ? 0.866   80.611  56.041 1.00 82.22  ? 260 ARG A NH2 1 
ATOM   1973  N N   . GLY A 1 253 ? -4.835  79.382  50.595 1.00 92.20  ? 261 GLY A N   1 
ATOM   1974  C CA  . GLY A 1 253 ? -4.504  79.344  49.181 1.00 72.41  ? 261 GLY A CA  1 
ATOM   1975  C C   . GLY A 1 253 ? -5.421  80.307  48.448 1.00 82.96  ? 261 GLY A C   1 
ATOM   1976  O O   . GLY A 1 253 ? -6.112  81.120  49.093 1.00 117.17 ? 261 GLY A O   1 
ATOM   1977  N N   . CYS A 1 254 ? -5.397  80.204  47.113 1.00 65.96  ? 262 CYS A N   1 
ATOM   1978  C CA  . CYS A 1 254 ? -6.279  81.022  46.291 1.00 68.22  ? 262 CYS A CA  1 
ATOM   1979  C C   . CYS A 1 254 ? -7.689  80.436  46.377 1.00 75.64  ? 262 CYS A C   1 
ATOM   1980  O O   . CYS A 1 254 ? -7.893  79.336  46.906 1.00 68.12  ? 262 CYS A O   1 
ATOM   1981  C CB  . CYS A 1 254 ? -5.769  81.091  44.853 1.00 69.21  ? 262 CYS A CB  1 
ATOM   1982  S SG  . CYS A 1 254 ? -5.579  79.456  44.072 1.00 71.93  ? 262 CYS A SG  1 
ATOM   1983  N N   . ARG A 1 255 ? -8.660  81.180  45.839 1.00 64.98  ? 263 ARG A N   1 
ATOM   1984  C CA  . ARG A 1 255 ? -10.023 80.673  45.808 1.00 62.23  ? 263 ARG A CA  1 
ATOM   1985  C C   . ARG A 1 255 ? -10.163 79.592  44.729 1.00 71.90  ? 263 ARG A C   1 
ATOM   1986  O O   . ARG A 1 255 ? -10.027 79.894  43.532 1.00 66.95  ? 263 ARG A O   1 
ATOM   1987  C CB  . ARG A 1 255 ? -10.996 81.833  45.616 1.00 56.19  ? 263 ARG A CB  1 
ATOM   1988  C CG  . ARG A 1 255 ? -10.908 82.936  46.653 1.00 43.39  ? 263 ARG A CG  1 
ATOM   1989  C CD  . ARG A 1 255 ? -11.745 84.160  46.233 1.00 58.92  ? 263 ARG A CD  1 
ATOM   1990  N NE  . ARG A 1 255 ? -12.134 84.840  47.474 1.00 60.18  ? 263 ARG A NE  1 
ATOM   1991  C CZ  . ARG A 1 255 ? -12.927 84.223  48.364 1.00 65.38  ? 263 ARG A CZ  1 
ATOM   1992  N NH1 . ARG A 1 255 ? -13.753 83.225  47.943 1.00 69.25  ? 263 ARG A NH1 1 
ATOM   1993  N NH2 . ARG A 1 255 ? -12.845 84.634  49.631 1.00 44.91  ? 263 ARG A NH2 1 
ATOM   1994  N N   . ALA A 1 256 ? -10.422 78.352  45.202 1.00 73.31  ? 264 ALA A N   1 
ATOM   1995  C CA  . ALA A 1 256 ? -10.730 77.128  44.454 1.00 71.41  ? 264 ALA A CA  1 
ATOM   1996  C C   . ALA A 1 256 ? -11.230 76.063  45.450 1.00 73.91  ? 264 ALA A C   1 
ATOM   1997  O O   . ALA A 1 256 ? -11.286 76.308  46.661 1.00 77.88  ? 264 ALA A O   1 
ATOM   1998  C CB  . ALA A 1 256 ? -9.523  76.649  43.651 1.00 72.11  ? 264 ALA A CB  1 
ATOM   1999  N N   . GLY A 1 257 ? -11.557 74.859  44.973 1.00 71.93  ? 265 GLY A N   1 
ATOM   2000  C CA  . GLY A 1 257 ? -12.014 73.803  45.868 1.00 73.27  ? 265 GLY A CA  1 
ATOM   2001  C C   . GLY A 1 257 ? -11.464 72.430  45.462 1.00 96.98  ? 265 GLY A C   1 
ATOM   2002  O O   . GLY A 1 257 ? -10.882 72.265  44.376 1.00 102.35 ? 265 GLY A O   1 
ATOM   2003  N N   . MET A 1 258 ? -11.664 71.433  46.340 1.00 80.66  ? 266 MET A N   1 
ATOM   2004  C CA  . MET A 1 258 ? -11.133 70.099  46.114 1.00 75.68  ? 266 MET A CA  1 
ATOM   2005  C C   . MET A 1 258 ? -12.108 69.085  46.679 1.00 69.31  ? 266 MET A C   1 
ATOM   2006  O O   . MET A 1 258 ? -12.788 69.376  47.665 1.00 84.01  ? 266 MET A O   1 
ATOM   2007  C CB  . MET A 1 258 ? -9.800  69.907  46.842 1.00 82.09  ? 266 MET A CB  1 
ATOM   2008  C CG  . MET A 1 258 ? -8.667  70.731  46.261 1.00 73.10  ? 266 MET A CG  1 
ATOM   2009  S SD  . MET A 1 258 ? -7.149  70.347  47.128 1.00 83.14  ? 266 MET A SD  1 
ATOM   2010  C CE  . MET A 1 258 ? -7.311  70.747  48.871 1.00 78.02  ? 266 MET A CE  1 
ATOM   2011  N N   . ILE A 1 259 ? -12.136 67.876  46.099 1.00 63.72  ? 267 ILE A N   1 
ATOM   2012  C CA  . ILE A 1 259 ? -13.009 66.817  46.604 1.00 82.28  ? 267 ILE A CA  1 
ATOM   2013  C C   . ILE A 1 259 ? -12.121 65.613  46.897 1.00 85.86  ? 267 ILE A C   1 
ATOM   2014  O O   . ILE A 1 259 ? -11.566 65.042  45.949 1.00 86.45  ? 267 ILE A O   1 
ATOM   2015  C CB  . ILE A 1 259 ? -14.106 66.453  45.564 1.00 90.35  ? 267 ILE A CB  1 
ATOM   2016  C CG1 . ILE A 1 259 ? -14.983 67.645  45.185 1.00 93.78  ? 267 ILE A CG1 1 
ATOM   2017  C CG2 . ILE A 1 259 ? -14.959 65.259  45.995 1.00 71.33  ? 267 ILE A CG2 1 
ATOM   2018  C CD1 . ILE A 1 259 ? -15.900 67.409  43.997 1.00 76.68  ? 267 ILE A CD1 1 
ATOM   2019  N N   . PHE A 1 260 ? -12.020 65.237  48.186 1.00 67.36  ? 268 PHE A N   1 
ATOM   2020  C CA  . PHE A 1 260 ? -11.388 63.973  48.565 1.00 86.74  ? 268 PHE A CA  1 
ATOM   2021  C C   . PHE A 1 260 ? -12.448 62.862  48.625 1.00 100.48 ? 268 PHE A C   1 
ATOM   2022  O O   . PHE A 1 260 ? -13.568 63.092  49.089 1.00 77.11  ? 268 PHE A O   1 
ATOM   2023  C CB  . PHE A 1 260 ? -10.690 64.110  49.920 1.00 79.52  ? 268 PHE A CB  1 
ATOM   2024  C CG  . PHE A 1 260 ? -9.591  65.153  49.959 1.00 84.12  ? 268 PHE A CG  1 
ATOM   2025  C CD1 . PHE A 1 260 ? -9.888  66.476  50.232 1.00 90.89  ? 268 PHE A CD1 1 
ATOM   2026  C CD2 . PHE A 1 260 ? -8.258  64.813  49.734 1.00 104.60 ? 268 PHE A CD2 1 
ATOM   2027  C CE1 . PHE A 1 260 ? -8.866  67.428  50.257 1.00 119.21 ? 268 PHE A CE1 1 
ATOM   2028  C CE2 . PHE A 1 260 ? -7.225  65.752  49.811 1.00 107.13 ? 268 PHE A CE2 1 
ATOM   2029  C CZ  . PHE A 1 260 ? -7.530  67.069  50.054 1.00 115.34 ? 268 PHE A CZ  1 
ATOM   2030  N N   . TYR A 1 261 ? -12.097 61.648  48.177 1.00 104.87 ? 269 TYR A N   1 
ATOM   2031  C CA  . TYR A 1 261 ? -13.044 60.543  48.146 1.00 92.86  ? 269 TYR A CA  1 
ATOM   2032  C C   . TYR A 1 261 ? -12.340 59.225  48.449 1.00 102.76 ? 269 TYR A C   1 
ATOM   2033  O O   . TYR A 1 261 ? -11.146 59.056  48.144 1.00 103.43 ? 269 TYR A O   1 
ATOM   2034  C CB  . TYR A 1 261 ? -13.671 60.423  46.759 1.00 88.94  ? 269 TYR A CB  1 
ATOM   2035  C CG  . TYR A 1 261 ? -12.670 60.564  45.620 1.00 95.60  ? 269 TYR A CG  1 
ATOM   2036  C CD1 . TYR A 1 261 ? -11.934 59.478  45.149 1.00 112.21 ? 269 TYR A CD1 1 
ATOM   2037  C CD2 . TYR A 1 261 ? -12.454 61.789  45.017 1.00 99.20  ? 269 TYR A CD2 1 
ATOM   2038  C CE1 . TYR A 1 261 ? -11.019 59.593  44.106 1.00 110.60 ? 269 TYR A CE1 1 
ATOM   2039  C CE2 . TYR A 1 261 ? -11.555 61.917  43.973 1.00 120.39 ? 269 TYR A CE2 1 
ATOM   2040  C CZ  . TYR A 1 261 ? -10.823 60.832  43.530 1.00 108.47 ? 269 TYR A CZ  1 
ATOM   2041  O OH  . TYR A 1 261 ? -9.950  61.025  42.505 1.00 100.99 ? 269 TYR A OH  1 
ATOM   2042  N N   . ARG A 1 262 ? -13.115 58.289  49.026 1.00 92.65  ? 270 ARG A N   1 
ATOM   2043  C CA  . ARG A 1 262 ? -12.573 56.981  49.381 1.00 111.87 ? 270 ARG A CA  1 
ATOM   2044  C C   . ARG A 1 262 ? -12.412 56.128  48.114 1.00 99.22  ? 270 ARG A C   1 
ATOM   2045  O O   . ARG A 1 262 ? -13.248 56.164  47.233 1.00 119.06 ? 270 ARG A O   1 
ATOM   2046  C CB  . ARG A 1 262 ? -13.175 56.304  50.630 1.00 109.13 ? 270 ARG A CB  1 
ATOM   2047  C CG  . ARG A 1 262 ? -12.141 55.310  51.177 1.00 95.61  ? 270 ARG A CG  1 
ATOM   2048  C CD  . ARG A 1 262 ? -12.176 54.491  52.464 1.00 62.00  ? 270 ARG A CD  1 
ATOM   2049  N NE  . ARG A 1 262 ? -12.069 55.492  53.546 1.00 116.08 ? 270 ARG A NE  1 
ATOM   2050  C CZ  . ARG A 1 262 ? -12.572 55.415  54.825 1.00 153.67 ? 270 ARG A CZ  1 
ATOM   2051  N NH1 . ARG A 1 262 ? -13.481 54.486  55.123 1.00 176.40 ? 270 ARG A NH1 1 
ATOM   2052  N NH2 . ARG A 1 262 ? -12.221 56.280  55.791 1.00 86.83  ? 270 ARG A NH2 1 
ATOM   2053  N N   . LYS A 1 263 ? -11.279 55.430  47.994 1.00 92.28  ? 271 LYS A N   1 
ATOM   2054  C CA  . LYS A 1 263 ? -11.035 54.383  47.013 1.00 103.01 ? 271 LYS A CA  1 
ATOM   2055  C C   . LYS A 1 263 ? -10.715 53.105  47.788 1.00 92.82  ? 271 LYS A C   1 
ATOM   2056  O O   . LYS A 1 263 ? -10.219 53.157  48.910 1.00 82.66  ? 271 LYS A O   1 
ATOM   2057  C CB  . LYS A 1 263 ? -9.738  54.625  46.235 1.00 102.43 ? 271 LYS A CB  1 
ATOM   2058  C CG  . LYS A 1 263 ? -9.381  55.999  45.746 1.00 87.81  ? 271 LYS A CG  1 
ATOM   2059  C CD  . LYS A 1 263 ? -8.643  56.153  44.411 1.00 88.24  ? 271 LYS A CD  1 
ATOM   2060  C CE  . LYS A 1 263 ? -7.197  55.711  44.348 1.00 90.10  ? 271 LYS A CE  1 
ATOM   2061  N NZ  . LYS A 1 263 ? -6.407  56.494  45.292 1.00 121.97 ? 271 LYS A NZ  1 
ATOM   2062  N N   . GLY A 1 264 ? -11.001 51.939  47.198 1.00 88.38  ? 272 GLY A N   1 
ATOM   2063  C CA  . GLY A 1 264 ? -10.629 50.679  47.824 1.00 88.11  ? 272 GLY A CA  1 
ATOM   2064  C C   . GLY A 1 264 ? -11.864 49.860  48.181 1.00 90.33  ? 272 GLY A C   1 
ATOM   2065  O O   . GLY A 1 264 ? -12.876 49.916  47.491 1.00 106.35 ? 272 GLY A O   1 
ATOM   2066  N N   . VAL A 1 265 ? -11.765 49.072  49.250 1.00 93.43  ? 273 VAL A N   1 
ATOM   2067  C CA  . VAL A 1 265 ? -12.861 48.191  49.621 1.00 94.44  ? 273 VAL A CA  1 
ATOM   2068  C C   . VAL A 1 265 ? -13.978 48.987  50.302 1.00 106.33 ? 273 VAL A C   1 
ATOM   2069  O O   . VAL A 1 265 ? -13.730 49.710  51.269 1.00 96.05  ? 273 VAL A O   1 
ATOM   2070  C CB  . VAL A 1 265 ? -12.357 47.096  50.569 1.00 86.44  ? 273 VAL A CB  1 
ATOM   2071  C CG1 . VAL A 1 265 ? -13.428 46.022  50.730 1.00 79.17  ? 273 VAL A CG1 1 
ATOM   2072  C CG2 . VAL A 1 265 ? -10.974 46.582  50.172 1.00 74.46  ? 273 VAL A CG2 1 
ATOM   2073  N N   . LYS A 1 266 ? -15.216 48.823  49.794 1.00 115.48 ? 274 LYS A N   1 
ATOM   2074  C CA  . LYS A 1 266 ? -16.409 49.354  50.441 1.00 104.77 ? 274 LYS A CA  1 
ATOM   2075  C C   . LYS A 1 266 ? -16.714 48.359  51.542 1.00 100.38 ? 274 LYS A C   1 
ATOM   2076  O O   . LYS A 1 266 ? -16.644 48.777  52.690 1.00 78.67  ? 274 LYS A O   1 
ATOM   2077  C CB  . LYS A 1 266 ? -17.583 49.700  49.502 1.00 92.76  ? 274 LYS A CB  1 
ATOM   2078  C CG  . LYS A 1 266 ? -18.632 50.782  49.873 1.00 62.51  ? 274 LYS A CG  1 
ATOM   2079  C CD  . LYS A 1 266 ? -20.050 50.205  50.092 1.00 79.41  ? 274 LYS A CD  1 
ATOM   2080  C CE  . LYS A 1 266 ? -20.383 49.461  51.429 1.00 66.46  ? 274 LYS A CE  1 
ATOM   2081  N NZ  . LYS A 1 266 ? -21.279 48.303  51.262 1.00 50.26  ? 274 LYS A NZ  1 
ATOM   2082  N N   . SER A 1 267 ? -16.887 47.085  51.198 1.00 122.81 ? 275 SER A N   1 
ATOM   2083  C CA  . SER A 1 267 ? -17.078 46.069  52.260 1.00 160.97 ? 275 SER A CA  1 
ATOM   2084  C C   . SER A 1 267 ? -17.008 44.660  51.682 1.00 158.10 ? 275 SER A C   1 
ATOM   2085  O O   . SER A 1 267 ? -17.558 44.441  50.594 1.00 153.31 ? 275 SER A O   1 
ATOM   2086  C CB  . SER A 1 267 ? -18.387 46.265  52.954 1.00 161.92 ? 275 SER A CB  1 
ATOM   2087  O OG  . SER A 1 267 ? -19.455 45.792  52.147 1.00 189.34 ? 275 SER A OG  1 
ATOM   2088  N N   . VAL A 1 268 ? -16.356 43.747  52.398 1.00 156.63 ? 276 VAL A N   1 
ATOM   2089  C CA  . VAL A 1 268 ? -16.375 42.331  51.951 1.00 130.45 ? 276 VAL A CA  1 
ATOM   2090  C C   . VAL A 1 268 ? -17.852 41.973  51.844 1.00 161.29 ? 276 VAL A C   1 
ATOM   2091  O O   . VAL A 1 268 ? -18.621 42.455  52.690 1.00 190.43 ? 276 VAL A O   1 
ATOM   2092  C CB  . VAL A 1 268 ? -15.649 41.423  52.958 1.00 94.84  ? 276 VAL A CB  1 
ATOM   2093  C CG1 . VAL A 1 268 ? -14.173 41.766  53.055 1.00 108.71 ? 276 VAL A CG1 1 
ATOM   2094  C CG2 . VAL A 1 268 ? -16.299 41.472  54.330 1.00 57.88  ? 276 VAL A CG2 1 
ATOM   2095  N N   . ASP A 1 269 ? -18.246 41.226  50.818 1.00 152.68 ? 277 ASP A N   1 
ATOM   2096  C CA  . ASP A 1 269 ? -19.658 40.775  50.753 1.00 170.69 ? 277 ASP A CA  1 
ATOM   2097  C C   . ASP A 1 269 ? -19.751 39.435  51.472 1.00 209.97 ? 277 ASP A C   1 
ATOM   2098  O O   . ASP A 1 269 ? -19.632 38.412  50.794 1.00 251.14 ? 277 ASP A O   1 
ATOM   2099  C CB  . ASP A 1 269 ? -20.151 40.639  49.314 1.00 148.93 ? 277 ASP A CB  1 
ATOM   2100  C CG  . ASP A 1 269 ? -21.608 40.225  49.231 1.00 160.80 ? 277 ASP A CG  1 
ATOM   2101  O OD1 . ASP A 1 269 ? -22.046 39.841  48.131 1.00 179.13 ? 277 ASP A OD1 1 
ATOM   2102  O OD2 . ASP A 1 269 ? -22.294 40.298  50.268 1.00 175.42 ? 277 ASP A OD2 1 
ATOM   2103  N N   . PRO A 1 270 ? -19.995 39.383  52.797 1.00 175.84 ? 278 PRO A N   1 
ATOM   2104  C CA  . PRO A 1 270 ? -19.985 38.113  53.504 1.00 152.67 ? 278 PRO A CA  1 
ATOM   2105  C C   . PRO A 1 270 ? -20.840 37.152  52.675 1.00 172.84 ? 278 PRO A C   1 
ATOM   2106  O O   . PRO A 1 270 ? -20.547 35.974  52.656 1.00 204.07 ? 278 PRO A O   1 
ATOM   2107  C CB  . PRO A 1 270 ? -20.656 38.449  54.836 1.00 30.00  ? 278 PRO A CB  1 
ATOM   2108  C CG  . PRO A 1 270 ? -20.332 39.908  55.046 1.00 30.00  ? 278 PRO A CG  1 
ATOM   2109  C CD  . PRO A 1 270 ? -20.356 40.509  53.657 1.00 30.00  ? 278 PRO A CD  1 
ATOM   2110  N N   . ALA A 1 271 ? -21.854 37.689  51.994 1.00 194.27 ? 279 ALA A N   1 
ATOM   2111  C CA  . ALA A 1 271 ? -22.718 36.846  51.140 1.00 194.97 ? 279 ALA A CA  1 
ATOM   2112  C C   . ALA A 1 271 ? -21.850 36.120  50.110 1.00 198.59 ? 279 ALA A C   1 
ATOM   2113  O O   . ALA A 1 271 ? -22.070 34.913  49.898 1.00 174.41 ? 279 ALA A O   1 
ATOM   2114  C CB  . ALA A 1 271 ? -23.790 37.682  50.458 1.00 30.00  ? 279 ALA A CB  1 
ATOM   2115  N N   . THR A 1 272 ? -20.903 36.832  49.498 1.00 216.80 ? 280 THR A N   1 
ATOM   2116  C CA  . THR A 1 272 ? -19.989 36.203  48.513 1.00 188.94 ? 280 THR A CA  1 
ATOM   2117  C C   . THR A 1 272 ? -18.635 35.960  49.173 1.00 170.31 ? 280 THR A C   1 
ATOM   2118  O O   . THR A 1 272 ? -18.092 34.852  49.016 1.00 142.62 ? 280 THR A O   1 
ATOM   2119  C CB  . THR A 1 272 ? -19.817 37.096  47.281 1.00 173.99 ? 280 THR A CB  1 
ATOM   2120  O OG1 . THR A 1 272 ? -19.193 38.308  47.705 1.00 203.05 ? 280 THR A OG1 1 
ATOM   2121  C CG2 . THR A 1 272 ? -21.127 37.404  46.590 1.00 138.09 ? 280 THR A CG2 1 
ATOM   2122  N N   . GLY A 1 273 ? -18.123 36.961  49.885 1.00 151.54 ? 281 GLY A N   1 
ATOM   2123  C CA  . GLY A 1 273 ? -16.803 36.841  50.525 1.00 148.07 ? 281 GLY A CA  1 
ATOM   2124  C C   . GLY A 1 273 ? -15.745 37.546  49.705 1.00 164.21 ? 281 GLY A C   1 
ATOM   2125  O O   . GLY A 1 273 ? -14.590 37.607  50.162 1.00 170.63 ? 281 GLY A O   1 
ATOM   2126  N N   . LYS A 1 274 ? -16.125 38.068  48.537 1.00 158.54 ? 282 LYS A N   1 
ATOM   2127  C CA  . LYS A 1 274 ? -15.158 38.838  47.715 1.00 147.12 ? 282 LYS A CA  1 
ATOM   2128  C C   . LYS A 1 274 ? -15.157 40.287  48.200 1.00 167.48 ? 282 LYS A C   1 
ATOM   2129  O O   . LYS A 1 274 ? -15.364 40.497  49.408 1.00 187.25 ? 282 LYS A O   1 
ATOM   2130  C CB  . LYS A 1 274 ? -15.490 38.742  46.226 1.00 133.42 ? 282 LYS A CB  1 
ATOM   2131  C CG  . LYS A 1 274 ? -14.341 39.103  45.296 1.00 111.53 ? 282 LYS A CG  1 
ATOM   2132  C CD  . LYS A 1 274 ? -13.024 38.503  45.738 1.00 107.86 ? 282 LYS A CD  1 
ATOM   2133  C CE  . LYS A 1 274 ? -11.852 38.945  44.889 1.00 116.31 ? 282 LYS A CE  1 
ATOM   2134  N NZ  . LYS A 1 274 ? -12.018 38.544  43.472 1.00 105.54 ? 282 LYS A NZ  1 
ATOM   2135  N N   . GLU A 1 275 ? -14.952 41.247  47.299 1.00 158.67 ? 283 GLU A N   1 
ATOM   2136  C CA  . GLU A 1 275 ? -14.819 42.654  47.754 1.00 142.73 ? 283 GLU A CA  1 
ATOM   2137  C C   . GLU A 1 275 ? -15.747 43.582  46.974 1.00 122.60 ? 283 GLU A C   1 
ATOM   2138  O O   . GLU A 1 275 ? -15.713 43.537  45.731 1.00 112.87 ? 283 GLU A O   1 
ATOM   2139  C CB  . GLU A 1 275 ? -13.366 43.102  47.601 1.00 147.49 ? 283 GLU A CB  1 
ATOM   2140  C CG  . GLU A 1 275 ? -12.437 42.491  48.634 1.00 148.89 ? 283 GLU A CG  1 
ATOM   2141  C CD  . GLU A 1 275 ? -10.986 42.926  48.520 1.00 127.81 ? 283 GLU A CD  1 
ATOM   2142  O OE1 . GLU A 1 275 ? -10.235 42.726  49.492 1.00 71.72  ? 283 GLU A OE1 1 
ATOM   2143  O OE2 . GLU A 1 275 ? -10.611 43.457  47.459 1.00 150.25 ? 283 GLU A OE2 1 
ATOM   2144  N N   . ILE A 1 276 ? -16.543 44.384  47.685 1.00 164.26 ? 284 ILE A N   1 
ATOM   2145  C CA  . ILE A 1 276 ? -17.396 45.402  47.011 1.00 141.51 ? 284 ILE A CA  1 
ATOM   2146  C C   . ILE A 1 276 ? -16.542 46.658  46.971 1.00 128.66 ? 284 ILE A C   1 
ATOM   2147  O O   . ILE A 1 276 ? -16.179 47.148  48.052 1.00 97.16  ? 284 ILE A O   1 
ATOM   2148  C CB  . ILE A 1 276 ? -18.716 45.622  47.769 1.00 118.68 ? 284 ILE A CB  1 
ATOM   2149  C CG1 . ILE A 1 276 ? -19.454 44.304  48.011 1.00 108.27 ? 284 ILE A CG1 1 
ATOM   2150  C CG2 . ILE A 1 276 ? -19.591 46.629  47.044 1.00 81.90  ? 284 ILE A CG2 1 
ATOM   2151  C CD1 . ILE A 1 276 ? -20.706 44.451  48.840 1.00 104.71 ? 284 ILE A CD1 1 
ATOM   2152  N N   . LEU A 1 277 ? -16.230 47.155  45.777 1.00 107.05 ? 285 LEU A N   1 
ATOM   2153  C CA  . LEU A 1 277 ? -15.282 48.264  45.727 1.00 93.14  ? 285 LEU A CA  1 
ATOM   2154  C C   . LEU A 1 277 ? -16.005 49.611  45.675 1.00 92.18  ? 285 LEU A C   1 
ATOM   2155  O O   . LEU A 1 277 ? -17.137 49.662  45.199 1.00 116.11 ? 285 LEU A O   1 
ATOM   2156  C CB  . LEU A 1 277 ? -14.242 48.060  44.617 1.00 95.61  ? 285 LEU A CB  1 
ATOM   2157  C CG  . LEU A 1 277 ? -13.156 47.034  44.976 1.00 70.47  ? 285 LEU A CG  1 
ATOM   2158  C CD1 . LEU A 1 277 ? -11.941 46.983  44.078 1.00 51.59  ? 285 LEU A CD1 1 
ATOM   2159  C CD2 . LEU A 1 277 ? -12.740 47.247  46.425 1.00 67.46  ? 285 LEU A CD2 1 
ATOM   2160  N N   . TYR A 1 278 ? -15.359 50.655  46.230 1.00 87.12  ? 286 TYR A N   1 
ATOM   2161  C CA  . TYR A 1 278 ? -15.759 52.046  46.110 1.00 85.88  ? 286 TYR A CA  1 
ATOM   2162  C C   . TYR A 1 278 ? -15.693 52.500  44.660 1.00 89.88  ? 286 TYR A C   1 
ATOM   2163  O O   . TYR A 1 278 ? -14.626 52.444  44.052 1.00 108.48 ? 286 TYR A O   1 
ATOM   2164  C CB  . TYR A 1 278 ? -14.852 53.022  46.872 1.00 77.42  ? 286 TYR A CB  1 
ATOM   2165  C CG  . TYR A 1 278 ? -15.216 53.051  48.348 1.00 90.50  ? 286 TYR A CG  1 
ATOM   2166  C CD1 . TYR A 1 278 ? -16.492 53.439  48.792 1.00 68.37  ? 286 TYR A CD1 1 
ATOM   2167  C CD2 . TYR A 1 278 ? -14.278 52.607  49.281 1.00 107.15 ? 286 TYR A CD2 1 
ATOM   2168  C CE1 . TYR A 1 278 ? -16.814 53.380  50.142 1.00 71.76  ? 286 TYR A CE1 1 
ATOM   2169  C CE2 . TYR A 1 278 ? -14.582 52.595  50.634 1.00 109.16 ? 286 TYR A CE2 1 
ATOM   2170  C CZ  . TYR A 1 278 ? -15.838 52.992  51.062 1.00 102.79 ? 286 TYR A CZ  1 
ATOM   2171  O OH  . TYR A 1 278 ? -16.018 52.913  52.416 1.00 123.15 ? 286 TYR A OH  1 
ATOM   2172  N N   . ASN A 1 279 ? -16.817 53.060  44.187 1.00 98.23  ? 287 ASN A N   1 
ATOM   2173  C CA  . ASN A 1 279 ? -16.873 53.614  42.854 1.00 85.36  ? 287 ASN A CA  1 
ATOM   2174  C C   . ASN A 1 279 ? -16.822 55.142  42.879 1.00 93.02  ? 287 ASN A C   1 
ATOM   2175  O O   . ASN A 1 279 ? -16.987 55.749  41.844 1.00 92.09  ? 287 ASN A O   1 
ATOM   2176  C CB  . ASN A 1 279 ? -18.032 53.051  42.042 1.00 80.82  ? 287 ASN A CB  1 
ATOM   2177  C CG  . ASN A 1 279 ? -17.703 53.198  40.573 1.00 121.76 ? 287 ASN A CG  1 
ATOM   2178  O OD1 . ASN A 1 279 ? -16.622 53.702  40.246 1.00 139.05 ? 287 ASN A OD1 1 
ATOM   2179  N ND2 . ASN A 1 279 ? -18.593 52.814  39.670 1.00 146.21 ? 287 ASN A ND2 1 
ATOM   2180  N N   . LEU A 1 280 ? -16.525 55.743  44.035 1.00 84.04  ? 288 LEU A N   1 
ATOM   2181  C CA  . LEU A 1 280 ? -16.568 57.180  44.239 1.00 78.76  ? 288 LEU A CA  1 
ATOM   2182  C C   . LEU A 1 280 ? -15.697 57.931  43.241 1.00 88.89  ? 288 LEU A C   1 
ATOM   2183  O O   . LEU A 1 280 ? -16.113 58.983  42.755 1.00 84.38  ? 288 LEU A O   1 
ATOM   2184  C CB  . LEU A 1 280 ? -16.193 57.554  45.672 1.00 63.52  ? 288 LEU A CB  1 
ATOM   2185  C CG  . LEU A 1 280 ? -17.059 56.896  46.754 1.00 71.85  ? 288 LEU A CG  1 
ATOM   2186  C CD1 . LEU A 1 280 ? -16.572 57.063  48.189 1.00 70.31  ? 288 LEU A CD1 1 
ATOM   2187  C CD2 . LEU A 1 280 ? -18.418 57.506  46.610 1.00 75.75  ? 288 LEU A CD2 1 
ATOM   2188  N N   . GLU A 1 281 ? -14.512 57.390  42.937 1.00 91.20  ? 289 GLU A N   1 
ATOM   2189  C CA  . GLU A 1 281 ? -13.593 58.046  42.013 1.00 77.67  ? 289 GLU A CA  1 
ATOM   2190  C C   . GLU A 1 281 ? -14.274 58.329  40.655 1.00 86.65  ? 289 GLU A C   1 
ATOM   2191  O O   . GLU A 1 281 ? -14.315 59.449  40.152 1.00 68.11  ? 289 GLU A O   1 
ATOM   2192  C CB  . GLU A 1 281 ? -12.261 57.313  41.897 1.00 53.78  ? 289 GLU A CB  1 
ATOM   2193  C CG  . GLU A 1 281 ? -11.313 58.054  40.972 1.00 69.96  ? 289 GLU A CG  1 
ATOM   2194  C CD  . GLU A 1 281 ? -9.867  57.575  41.038 1.00 87.51  ? 289 GLU A CD  1 
ATOM   2195  O OE1 . GLU A 1 281 ? -9.636  56.363  40.914 1.00 77.70  ? 289 GLU A OE1 1 
ATOM   2196  O OE2 . GLU A 1 281 ? -8.950  58.414  41.184 1.00 91.79  ? 289 GLU A OE2 1 
ATOM   2197  N N   . SER A 1 282 ? -14.822 57.308  40.015 1.00 81.39  ? 290 SER A N   1 
ATOM   2198  C CA  . SER A 1 282 ? -15.411 57.595  38.711 1.00 85.83  ? 290 SER A CA  1 
ATOM   2199  C C   . SER A 1 282 ? -16.634 58.516  38.823 1.00 92.34  ? 290 SER A C   1 
ATOM   2200  O O   . SER A 1 282 ? -16.758 59.498  38.091 1.00 94.40  ? 290 SER A O   1 
ATOM   2201  C CB  . SER A 1 282 ? -15.674 56.335  37.909 1.00 81.32  ? 290 SER A CB  1 
ATOM   2202  O OG  . SER A 1 282 ? -16.946 56.341  37.278 1.00 96.42  ? 290 SER A OG  1 
ATOM   2203  N N   . LEU A 1 283 ? -17.521 58.254  39.791 1.00 75.74  ? 291 LEU A N   1 
ATOM   2204  C CA  . LEU A 1 283 ? -18.727 59.060  39.950 1.00 65.42  ? 291 LEU A CA  1 
ATOM   2205  C C   . LEU A 1 283 ? -18.372 60.541  40.095 1.00 65.44  ? 291 LEU A C   1 
ATOM   2206  O O   . LEU A 1 283 ? -18.826 61.388  39.310 1.00 53.67  ? 291 LEU A O   1 
ATOM   2207  C CB  . LEU A 1 283 ? -19.517 58.565  41.160 1.00 52.94  ? 291 LEU A CB  1 
ATOM   2208  C CG  . LEU A 1 283 ? -20.112 57.163  40.989 1.00 41.88  ? 291 LEU A CG  1 
ATOM   2209  C CD1 . LEU A 1 283 ? -20.732 56.600  42.180 1.00 37.25  ? 291 LEU A CD1 1 
ATOM   2210  C CD2 . LEU A 1 283 ? -21.200 57.179  39.950 1.00 41.85  ? 291 LEU A CD2 1 
ATOM   2211  N N   . ILE A 1 284 ? -17.540 60.842  41.105 1.00 54.56  ? 292 ILE A N   1 
ATOM   2212  C CA  . ILE A 1 284 ? -17.188 62.223  41.372 1.00 63.72  ? 292 ILE A CA  1 
ATOM   2213  C C   . ILE A 1 284 ? -16.479 62.821  40.158 1.00 77.84  ? 292 ILE A C   1 
ATOM   2214  O O   . ILE A 1 284 ? -16.865 63.876  39.669 1.00 91.43  ? 292 ILE A O   1 
ATOM   2215  C CB  . ILE A 1 284 ? -16.383 62.354  42.668 1.00 60.42  ? 292 ILE A CB  1 
ATOM   2216  C CG1 . ILE A 1 284 ? -17.225 61.932  43.852 1.00 73.17  ? 292 ILE A CG1 1 
ATOM   2217  C CG2 . ILE A 1 284 ? -15.948 63.808  42.794 1.00 81.54  ? 292 ILE A CG2 1 
ATOM   2218  C CD1 . ILE A 1 284 ? -16.480 61.785  45.158 1.00 85.92  ? 292 ILE A CD1 1 
ATOM   2219  N N   . ASN A 1 285 ? -15.499 62.084  39.640 1.00 68.90  ? 293 ASN A N   1 
ATOM   2220  C CA  . ASN A 1 285 ? -14.755 62.537  38.488 1.00 74.52  ? 293 ASN A CA  1 
ATOM   2221  C C   . ASN A 1 285 ? -15.692 62.862  37.334 1.00 89.09  ? 293 ASN A C   1 
ATOM   2222  O O   . ASN A 1 285 ? -15.530 63.919  36.714 1.00 110.03 ? 293 ASN A O   1 
ATOM   2223  C CB  . ASN A 1 285 ? -13.583 61.630  38.149 1.00 71.54  ? 293 ASN A CB  1 
ATOM   2224  C CG  . ASN A 1 285 ? -12.446 61.911  39.095 1.00 88.24  ? 293 ASN A CG  1 
ATOM   2225  O OD1 . ASN A 1 285 ? -12.128 63.087  39.328 1.00 65.27  ? 293 ASN A OD1 1 
ATOM   2226  N ND2 . ASN A 1 285 ? -11.823 60.872  39.641 1.00 101.65 ? 293 ASN A ND2 1 
ATOM   2227  N N   . SER A 1 286 ? -16.665 61.981  37.076 1.00 69.28  ? 294 SER A N   1 
ATOM   2228  C CA  . SER A 1 286 ? -17.507 62.197  35.902 1.00 81.54  ? 294 SER A CA  1 
ATOM   2229  C C   . SER A 1 286 ? -18.417 63.403  36.135 1.00 73.35  ? 294 SER A C   1 
ATOM   2230  O O   . SER A 1 286 ? -18.736 64.139  35.194 1.00 78.70  ? 294 SER A O   1 
ATOM   2231  C CB  . SER A 1 286 ? -18.310 60.978  35.512 1.00 79.52  ? 294 SER A CB  1 
ATOM   2232  O OG  . SER A 1 286 ? -17.820 59.744  36.051 1.00 73.16  ? 294 SER A OG  1 
ATOM   2233  N N   . ALA A 1 287 ? -18.786 63.594  37.409 1.00 63.37  ? 295 ALA A N   1 
ATOM   2234  C CA  . ALA A 1 287 ? -19.661 64.690  37.791 1.00 79.04  ? 295 ALA A CA  1 
ATOM   2235  C C   . ALA A 1 287 ? -18.970 66.018  37.494 1.00 73.90  ? 295 ALA A C   1 
ATOM   2236  O O   . ALA A 1 287 ? -19.540 66.902  36.854 1.00 58.14  ? 295 ALA A O   1 
ATOM   2237  C CB  . ALA A 1 287 ? -20.015 64.578  39.261 1.00 84.23  ? 295 ALA A CB  1 
ATOM   2238  N N   . VAL A 1 288 ? -17.727 66.125  37.961 1.00 68.27  ? 296 VAL A N   1 
ATOM   2239  C CA  . VAL A 1 288 ? -16.956 67.324  37.752 1.00 63.67  ? 296 VAL A CA  1 
ATOM   2240  C C   . VAL A 1 288 ? -16.753 67.557  36.267 1.00 58.80  ? 296 VAL A C   1 
ATOM   2241  O O   . VAL A 1 288 ? -16.908 68.693  35.807 1.00 68.56  ? 296 VAL A O   1 
ATOM   2242  C CB  . VAL A 1 288 ? -15.604 67.269  38.464 1.00 56.89  ? 296 VAL A CB  1 
ATOM   2243  C CG1 . VAL A 1 288 ? -14.834 68.548  38.126 1.00 53.59  ? 296 VAL A CG1 1 
ATOM   2244  C CG2 . VAL A 1 288 ? -15.821 67.039  39.967 1.00 48.92  ? 296 VAL A CG2 1 
ATOM   2245  N N   . PHE A 1 289 ? -16.452 66.481  35.532 1.00 38.01  ? 297 PHE A N   1 
ATOM   2246  C CA  . PHE A 1 289 ? -16.205 66.640  34.100 1.00 51.54  ? 297 PHE A CA  1 
ATOM   2247  C C   . PHE A 1 289 ? -16.443 65.289  33.435 1.00 57.00  ? 297 PHE A C   1 
ATOM   2248  O O   . PHE A 1 289 ? -15.866 64.281  33.866 1.00 55.52  ? 297 PHE A O   1 
ATOM   2249  C CB  . PHE A 1 289 ? -14.810 67.182  33.681 1.00 52.67  ? 297 PHE A CB  1 
ATOM   2250  C CG  . PHE A 1 289 ? -14.708 67.430  32.194 1.00 45.87  ? 297 PHE A CG  1 
ATOM   2251  C CD1 . PHE A 1 289 ? -15.071 68.645  31.656 1.00 67.30  ? 297 PHE A CD1 1 
ATOM   2252  C CD2 . PHE A 1 289 ? -14.362 66.433  31.299 1.00 56.79  ? 297 PHE A CD2 1 
ATOM   2253  C CE1 . PHE A 1 289 ? -15.045 68.877  30.263 1.00 59.23  ? 297 PHE A CE1 1 
ATOM   2254  C CE2 . PHE A 1 289 ? -14.324 66.646  29.900 1.00 59.46  ? 297 PHE A CE2 1 
ATOM   2255  C CZ  . PHE A 1 289 ? -14.652 67.887  29.389 1.00 51.55  ? 297 PHE A CZ  1 
ATOM   2256  N N   . PRO A 1 290 ? -17.228 65.204  32.331 1.00 65.83  ? 298 PRO A N   1 
ATOM   2257  C CA  . PRO A 1 290 ? -17.863 66.352  31.631 1.00 67.79  ? 298 PRO A CA  1 
ATOM   2258  C C   . PRO A 1 290 ? -19.291 66.665  32.132 1.00 86.51  ? 298 PRO A C   1 
ATOM   2259  O O   . PRO A 1 290 ? -20.263 66.969  31.409 1.00 91.93  ? 298 PRO A O   1 
ATOM   2260  C CB  . PRO A 1 290 ? -17.898 65.726  30.239 1.00 56.14  ? 298 PRO A CB  1 
ATOM   2261  C CG  . PRO A 1 290 ? -18.438 64.321  30.555 1.00 55.50  ? 298 PRO A CG  1 
ATOM   2262  C CD  . PRO A 1 290 ? -17.554 63.896  31.721 1.00 60.08  ? 298 PRO A CD  1 
ATOM   2263  N N   . GLY A 1 291 ? -19.458 66.577  33.435 1.00 62.44  ? 299 GLY A N   1 
ATOM   2264  C CA  . GLY A 1 291 ? -20.807 66.741  33.913 1.00 55.69  ? 299 GLY A CA  1 
ATOM   2265  C C   . GLY A 1 291 ? -21.094 68.203  34.158 1.00 66.25  ? 299 GLY A C   1 
ATOM   2266  O O   . GLY A 1 291 ? -22.043 68.708  33.584 1.00 96.24  ? 299 GLY A O   1 
ATOM   2267  N N   . LEU A 1 292 ? -20.285 68.855  35.009 1.00 57.59  ? 300 LEU A N   1 
ATOM   2268  C CA  . LEU A 1 292 ? -20.617 70.191  35.482 1.00 52.23  ? 300 LEU A CA  1 
ATOM   2269  C C   . LEU A 1 292 ? -19.638 71.224  34.949 1.00 67.02  ? 300 LEU A C   1 
ATOM   2270  O O   . LEU A 1 292 ? -20.030 72.347  34.655 1.00 106.47 ? 300 LEU A O   1 
ATOM   2271  C CB  . LEU A 1 292 ? -20.595 70.209  37.002 1.00 57.75  ? 300 LEU A CB  1 
ATOM   2272  C CG  . LEU A 1 292 ? -21.766 69.487  37.670 1.00 72.24  ? 300 LEU A CG  1 
ATOM   2273  C CD1 . LEU A 1 292 ? -21.674 69.465  39.244 1.00 49.17  ? 300 LEU A CD1 1 
ATOM   2274  C CD2 . LEU A 1 292 ? -22.934 70.326  37.194 1.00 55.40  ? 300 LEU A CD2 1 
ATOM   2275  N N   . GLN A 1 293 ? -18.348 70.881  34.879 1.00 67.50  ? 301 GLN A N   1 
ATOM   2276  C CA  . GLN A 1 293 ? -17.350 71.911  34.635 1.00 73.58  ? 301 GLN A CA  1 
ATOM   2277  C C   . GLN A 1 293 ? -16.880 71.830  33.183 1.00 70.53  ? 301 GLN A C   1 
ATOM   2278  O O   . GLN A 1 293 ? -17.199 70.875  32.490 1.00 80.86  ? 301 GLN A O   1 
ATOM   2279  C CB  . GLN A 1 293 ? -16.213 71.855  35.654 1.00 71.72  ? 301 GLN A CB  1 
ATOM   2280  C CG  . GLN A 1 293 ? -16.697 72.080  37.080 1.00 73.36  ? 301 GLN A CG  1 
ATOM   2281  C CD  . GLN A 1 293 ? -15.567 72.505  38.001 1.00 87.30  ? 301 GLN A CD  1 
ATOM   2282  O OE1 . GLN A 1 293 ? -15.786 73.108  39.064 1.00 75.50  ? 301 GLN A OE1 1 
ATOM   2283  N NE2 . GLN A 1 293 ? -14.351 72.212  37.558 1.00 101.04 ? 301 GLN A NE2 1 
ATOM   2284  N N   . GLY A 1 294 ? -16.172 72.869  32.717 1.00 60.01  ? 302 GLY A N   1 
ATOM   2285  C CA  . GLY A 1 294 ? -15.451 72.763  31.472 1.00 58.39  ? 302 GLY A CA  1 
ATOM   2286  C C   . GLY A 1 294 ? -13.951 72.791  31.734 1.00 75.47  ? 302 GLY A C   1 
ATOM   2287  O O   . GLY A 1 294 ? -13.429 72.052  32.583 1.00 108.98 ? 302 GLY A O   1 
ATOM   2288  N N   . GLY A 1 295 ? -13.288 73.719  31.047 1.00 90.68  ? 303 GLY A N   1 
ATOM   2289  C CA  . GLY A 1 295 ? -11.847 73.876  31.153 1.00 114.86 ? 303 GLY A CA  1 
ATOM   2290  C C   . GLY A 1 295 ? -11.411 74.066  32.597 1.00 94.78  ? 303 GLY A C   1 
ATOM   2291  O O   . GLY A 1 295 ? -11.904 74.957  33.281 1.00 108.26 ? 303 GLY A O   1 
ATOM   2292  N N   . PRO A 1 296 ? -10.459 73.248  33.088 1.00 70.29  ? 304 PRO A N   1 
ATOM   2293  C CA  . PRO A 1 296 ? -9.956  73.434  34.447 1.00 69.33  ? 304 PRO A CA  1 
ATOM   2294  C C   . PRO A 1 296 ? -9.293  74.811  34.539 1.00 67.65  ? 304 PRO A C   1 
ATOM   2295  O O   . PRO A 1 296 ? -8.726  75.272  33.510 1.00 75.74  ? 304 PRO A O   1 
ATOM   2296  C CB  . PRO A 1 296 ? -8.931  72.285  34.537 1.00 68.09  ? 304 PRO A CB  1 
ATOM   2297  C CG  . PRO A 1 296 ? -9.513  71.235  33.625 1.00 108.62 ? 304 PRO A CG  1 
ATOM   2298  C CD  . PRO A 1 296 ? -9.865  72.095  32.383 1.00 93.35  ? 304 PRO A CD  1 
ATOM   2299  N N   . HIS A 1 297 ? -9.327  75.428  35.764 1.00 42.20  ? 305 HIS A N   1 
ATOM   2300  C CA  . HIS A 1 297 ? -8.575  76.670  35.929 1.00 68.40  ? 305 HIS A CA  1 
ATOM   2301  C C   . HIS A 1 297 ? -7.128  76.397  36.316 1.00 87.11  ? 305 HIS A C   1 
ATOM   2302  O O   . HIS A 1 297 ? -6.842  76.414  37.505 1.00 78.08  ? 305 HIS A O   1 
ATOM   2303  C CB  . HIS A 1 297 ? -9.275  77.681  36.842 1.00 67.42  ? 305 HIS A CB  1 
ATOM   2304  C CG  . HIS A 1 297 ? -10.498 78.212  36.171 1.00 92.43  ? 305 HIS A CG  1 
ATOM   2305  N ND1 . HIS A 1 297 ? -11.487 78.943  36.763 1.00 97.26  ? 305 HIS A ND1 1 
ATOM   2306  C CD2 . HIS A 1 297 ? -10.868 78.131  34.891 1.00 125.48 ? 305 HIS A CD2 1 
ATOM   2307  C CE1 . HIS A 1 297 ? -12.430 79.236  35.879 1.00 86.78  ? 305 HIS A CE1 1 
ATOM   2308  N NE2 . HIS A 1 297 ? -12.073 78.769  34.733 1.00 118.25 ? 305 HIS A NE2 1 
ATOM   2309  N N   . ASN A 1 298 ? -6.230  76.153  35.341 1.00 95.35  ? 306 ASN A N   1 
ATOM   2310  C CA  . ASN A 1 298 ? -4.951  75.566  35.726 1.00 97.85  ? 306 ASN A CA  1 
ATOM   2311  C C   . ASN A 1 298 ? -4.147  76.505  36.631 1.00 108.99 ? 306 ASN A C   1 
ATOM   2312  O O   . ASN A 1 298 ? -3.421  76.077  37.538 1.00 81.86  ? 306 ASN A O   1 
ATOM   2313  C CB  . ASN A 1 298 ? -4.165  75.076  34.524 1.00 93.11  ? 306 ASN A CB  1 
ATOM   2314  C CG  . ASN A 1 298 ? -4.843  73.907  33.839 1.00 126.89 ? 306 ASN A CG  1 
ATOM   2315  O OD1 . ASN A 1 298 ? -4.854  72.776  34.377 1.00 83.15  ? 306 ASN A OD1 1 
ATOM   2316  N ND2 . ASN A 1 298 ? -5.340  74.157  32.621 1.00 158.17 ? 306 ASN A ND2 1 
ATOM   2317  N N   . HIS A 1 299 ? -4.280  77.803  36.358 1.00 101.10 ? 307 HIS A N   1 
ATOM   2318  C CA  . HIS A 1 299 ? -3.606  78.818  37.147 1.00 86.09  ? 307 HIS A CA  1 
ATOM   2319  C C   . HIS A 1 299 ? -4.082  78.776  38.599 1.00 97.63  ? 307 HIS A C   1 
ATOM   2320  O O   . HIS A 1 299 ? -3.301  79.064  39.510 1.00 84.90  ? 307 HIS A O   1 
ATOM   2321  C CB  . HIS A 1 299 ? -3.855  80.183  36.512 1.00 100.60 ? 307 HIS A CB  1 
ATOM   2322  C CG  . HIS A 1 299 ? -5.302  80.517  36.391 1.00 86.28  ? 307 HIS A CG  1 
ATOM   2323  N ND1 . HIS A 1 299 ? -6.203  79.941  35.523 1.00 72.48  ? 307 HIS A ND1 1 
ATOM   2324  C CD2 . HIS A 1 299 ? -5.981  81.384  37.111 1.00 77.23  ? 307 HIS A CD2 1 
ATOM   2325  C CE1 . HIS A 1 299 ? -7.374  80.500  35.710 1.00 79.76  ? 307 HIS A CE1 1 
ATOM   2326  N NE2 . HIS A 1 299 ? -7.253  81.389  36.657 1.00 82.39  ? 307 HIS A NE2 1 
ATOM   2327  N N   . ALA A 1 300 ? -5.360  78.409  38.807 1.00 101.39 ? 308 ALA A N   1 
ATOM   2328  C CA  . ALA A 1 300 ? -5.870  78.201  40.162 1.00 78.42  ? 308 ALA A CA  1 
ATOM   2329  C C   . ALA A 1 300 ? -5.296  76.941  40.788 1.00 66.99  ? 308 ALA A C   1 
ATOM   2330  O O   . ALA A 1 300 ? -4.951  76.965  41.975 1.00 64.18  ? 308 ALA A O   1 
ATOM   2331  C CB  . ALA A 1 300 ? -7.371  78.151  40.221 1.00 67.44  ? 308 ALA A CB  1 
ATOM   2332  N N   . ILE A 1 301 ? -5.154  75.883  39.963 1.00 65.97  ? 309 ILE A N   1 
ATOM   2333  C CA  . ILE A 1 301 ? -4.661  74.616  40.481 1.00 99.57  ? 309 ILE A CA  1 
ATOM   2334  C C   . ILE A 1 301 ? -3.217  74.807  40.944 1.00 110.80 ? 309 ILE A C   1 
ATOM   2335  O O   . ILE A 1 301 ? -2.826  74.286  42.005 1.00 117.10 ? 309 ILE A O   1 
ATOM   2336  C CB  . ILE A 1 301 ? -4.815  73.479  39.456 1.00 90.41  ? 309 ILE A CB  1 
ATOM   2337  C CG1 . ILE A 1 301 ? -6.238  73.079  39.309 1.00 72.58  ? 309 ILE A CG1 1 
ATOM   2338  C CG2 . ILE A 1 301 ? -3.984  72.255  39.844 1.00 87.12  ? 309 ILE A CG2 1 
ATOM   2339  C CD1 . ILE A 1 301 ? -6.472  72.272  38.053 1.00 79.31  ? 309 ILE A CD1 1 
ATOM   2340  N N   . ALA A 1 302 ? -2.470  75.606  40.157 1.00 80.82  ? 310 ALA A N   1 
ATOM   2341  C CA  . ALA A 1 302 ? -1.099  75.947  40.521 1.00 95.34  ? 310 ALA A CA  1 
ATOM   2342  C C   . ALA A 1 302 ? -1.071  76.599  41.905 1.00 103.50 ? 310 ALA A C   1 
ATOM   2343  O O   . ALA A 1 302 ? -0.280  76.226  42.779 1.00 94.13  ? 310 ALA A O   1 
ATOM   2344  C CB  . ALA A 1 302 ? -0.503  76.864  39.465 1.00 90.12  ? 310 ALA A CB  1 
ATOM   2345  N N   . GLY A 1 303 ? -1.934  77.610  42.081 1.00 121.03 ? 311 GLY A N   1 
ATOM   2346  C CA  . GLY A 1 303 ? -2.027  78.336  43.337 1.00 142.91 ? 311 GLY A CA  1 
ATOM   2347  C C   . GLY A 1 303 ? -2.303  77.393  44.503 1.00 135.64 ? 311 GLY A C   1 
ATOM   2348  O O   . GLY A 1 303 ? -1.715  77.532  45.580 1.00 134.68 ? 311 GLY A O   1 
ATOM   2349  N N   . VAL A 1 304 ? -3.187  76.422  44.257 1.00 97.95  ? 312 VAL A N   1 
ATOM   2350  C CA  . VAL A 1 304 ? -3.566  75.482  45.296 1.00 80.19  ? 312 VAL A CA  1 
ATOM   2351  C C   . VAL A 1 304 ? -2.368  74.613  45.651 1.00 88.33  ? 312 VAL A C   1 
ATOM   2352  O O   . VAL A 1 304 ? -2.118  74.324  46.828 1.00 67.54  ? 312 VAL A O   1 
ATOM   2353  C CB  . VAL A 1 304 ? -4.750  74.618  44.841 1.00 64.02  ? 312 VAL A CB  1 
ATOM   2354  C CG1 . VAL A 1 304 ? -5.094  73.558  45.916 1.00 62.56  ? 312 VAL A CG1 1 
ATOM   2355  C CG2 . VAL A 1 304 ? -5.925  75.529  44.489 1.00 46.70  ? 312 VAL A CG2 1 
ATOM   2356  N N   . ALA A 1 305 ? -1.669  74.176  44.601 1.00 107.60 ? 313 ALA A N   1 
ATOM   2357  C CA  . ALA A 1 305 ? -0.482  73.365  44.786 1.00 112.24 ? 313 ALA A CA  1 
ATOM   2358  C C   . ALA A 1 305 ? 0.468   74.109  45.727 1.00 94.94  ? 313 ALA A C   1 
ATOM   2359  O O   . ALA A 1 305 ? 0.850   73.566  46.763 1.00 64.37  ? 313 ALA A O   1 
ATOM   2360  C CB  . ALA A 1 305 ? 0.142   73.034  43.439 1.00 114.46 ? 313 ALA A CB  1 
ATOM   2361  N N   . VAL A 1 306 ? 0.786   75.369  45.387 1.00 78.61  ? 314 VAL A N   1 
ATOM   2362  C CA  . VAL A 1 306 ? 1.729   76.178  46.138 1.00 92.82  ? 314 VAL A CA  1 
ATOM   2363  C C   . VAL A 1 306 ? 1.297   76.244  47.602 1.00 97.16  ? 314 VAL A C   1 
ATOM   2364  O O   . VAL A 1 306 ? 2.126   76.082  48.517 1.00 106.94 ? 314 VAL A O   1 
ATOM   2365  C CB  . VAL A 1 306 ? 1.912   77.590  45.563 1.00 99.77  ? 314 VAL A CB  1 
ATOM   2366  C CG1 . VAL A 1 306 ? 2.649   78.466  46.569 1.00 90.34  ? 314 VAL A CG1 1 
ATOM   2367  C CG2 . VAL A 1 306 ? 2.637   77.562  44.218 1.00 88.00  ? 314 VAL A CG2 1 
ATOM   2368  N N   . ALA A 1 307 ? -0.012  76.460  47.797 1.00 75.71  ? 315 ALA A N   1 
ATOM   2369  C CA  . ALA A 1 307 ? -0.599  76.510  49.132 1.00 77.96  ? 315 ALA A CA  1 
ATOM   2370  C C   . ALA A 1 307 ? -0.367  75.219  49.916 1.00 66.55  ? 315 ALA A C   1 
ATOM   2371  O O   . ALA A 1 307 ? -0.039  75.280  51.112 1.00 61.03  ? 315 ALA A O   1 
ATOM   2372  C CB  . ALA A 1 307 ? -2.064  76.819  49.032 1.00 84.51  ? 315 ALA A CB  1 
ATOM   2373  N N   . LEU A 1 308 ? -0.590  74.084  49.232 1.00 63.86  ? 316 LEU A N   1 
ATOM   2374  C CA  . LEU A 1 308 ? -0.498  72.771  49.846 1.00 77.81  ? 316 LEU A CA  1 
ATOM   2375  C C   . LEU A 1 308 ? 0.942   72.529  50.294 1.00 90.46  ? 316 LEU A C   1 
ATOM   2376  O O   . LEU A 1 308 ? 1.184   71.956  51.357 1.00 83.81  ? 316 LEU A O   1 
ATOM   2377  C CB  . LEU A 1 308 ? -0.966  71.720  48.849 1.00 93.83  ? 316 LEU A CB  1 
ATOM   2378  C CG  . LEU A 1 308 ? -2.478  71.604  48.644 1.00 114.58 ? 316 LEU A CG  1 
ATOM   2379  C CD1 . LEU A 1 308 ? -2.771  70.701  47.455 1.00 116.65 ? 316 LEU A CD1 1 
ATOM   2380  C CD2 . LEU A 1 308 ? -3.099  71.024  49.900 1.00 105.99 ? 316 LEU A CD2 1 
ATOM   2381  N N   . LYS A 1 309 ? 1.889   72.973  49.464 1.00 91.20  ? 317 LYS A N   1 
ATOM   2382  C CA  . LYS A 1 309 ? 3.287   72.833  49.806 1.00 96.41  ? 317 LYS A CA  1 
ATOM   2383  C C   . LYS A 1 309 ? 3.548   73.600  51.093 1.00 91.27  ? 317 LYS A C   1 
ATOM   2384  O O   . LYS A 1 309 ? 4.269   73.119  51.960 1.00 116.53 ? 317 LYS A O   1 
ATOM   2385  C CB  . LYS A 1 309 ? 4.291   73.297  48.750 1.00 92.33  ? 317 LYS A CB  1 
ATOM   2386  C CG  . LYS A 1 309 ? 5.692   73.228  49.383 1.00 87.85  ? 317 LYS A CG  1 
ATOM   2387  C CD  . LYS A 1 309 ? 6.772   74.131  48.812 1.00 94.84  ? 317 LYS A CD  1 
ATOM   2388  C CE  . LYS A 1 309 ? 8.125   73.531  48.891 1.00 73.19  ? 317 LYS A CE  1 
ATOM   2389  N NZ  . LYS A 1 309 ? 8.882   74.423  48.017 1.00 83.53  ? 317 LYS A NZ  1 
ATOM   2390  N N   . GLN A 1 310 ? 3.008   74.813  51.196 1.00 79.84  ? 318 GLN A N   1 
ATOM   2391  C CA  . GLN A 1 310 ? 3.200   75.584  52.418 1.00 88.71  ? 318 GLN A CA  1 
ATOM   2392  C C   . GLN A 1 310 ? 2.526   74.920  53.600 1.00 98.19  ? 318 GLN A C   1 
ATOM   2393  O O   . GLN A 1 310 ? 3.034   75.015  54.705 1.00 125.99 ? 318 GLN A O   1 
ATOM   2394  C CB  . GLN A 1 310 ? 2.674   77.004  52.345 1.00 65.40  ? 318 GLN A CB  1 
ATOM   2395  C CG  . GLN A 1 310 ? 3.482   77.735  51.284 1.00 56.11  ? 318 GLN A CG  1 
ATOM   2396  C CD  . GLN A 1 310 ? 2.935   79.092  51.008 1.00 56.57  ? 318 GLN A CD  1 
ATOM   2397  O OE1 . GLN A 1 310 ? 3.442   79.729  50.083 1.00 79.56  ? 318 GLN A OE1 1 
ATOM   2398  N NE2 . GLN A 1 310 ? 1.872   79.445  51.747 1.00 81.38  ? 318 GLN A NE2 1 
ATOM   2399  N N   . ALA A 1 311 ? 1.397   74.263  53.342 1.00 99.26  ? 319 ALA A N   1 
ATOM   2400  C CA  . ALA A 1 311 ? 0.637   73.589  54.381 1.00 86.73  ? 319 ALA A CA  1 
ATOM   2401  C C   . ALA A 1 311 ? 1.455   72.499  55.057 1.00 95.45  ? 319 ALA A C   1 
ATOM   2402  O O   . ALA A 1 311 ? 1.145   72.116  56.174 1.00 138.13 ? 319 ALA A O   1 
ATOM   2403  C CB  . ALA A 1 311 ? -0.643  73.032  53.831 1.00 80.89  ? 319 ALA A CB  1 
ATOM   2404  N N   . MET A 1 312 ? 2.465   71.967  54.366 1.00 96.13  ? 320 MET A N   1 
ATOM   2405  C CA  . MET A 1 312 ? 3.235   70.857  54.897 1.00 91.99  ? 320 MET A CA  1 
ATOM   2406  C C   . MET A 1 312 ? 4.497   71.343  55.624 1.00 98.73  ? 320 MET A C   1 
ATOM   2407  O O   . MET A 1 312 ? 5.243   70.514  56.125 1.00 163.94 ? 320 MET A O   1 
ATOM   2408  C CB  . MET A 1 312 ? 3.561   69.863  53.782 1.00 66.60  ? 320 MET A CB  1 
ATOM   2409  C CG  . MET A 1 312 ? 2.391   68.978  53.431 1.00 85.39  ? 320 MET A CG  1 
ATOM   2410  S SD  . MET A 1 312 ? 2.652   67.942  51.965 1.00 108.36 ? 320 MET A SD  1 
ATOM   2411  C CE  . MET A 1 312 ? 3.373   69.248  50.953 1.00 76.24  ? 320 MET A CE  1 
ATOM   2412  N N   . THR A 1 313 ? 4.718   72.660  55.725 1.00 70.88  ? 321 THR A N   1 
ATOM   2413  C CA  . THR A 1 313 ? 5.811   73.234  56.496 1.00 83.07  ? 321 THR A CA  1 
ATOM   2414  C C   . THR A 1 313 ? 5.490   73.300  57.997 1.00 80.13  ? 321 THR A C   1 
ATOM   2415  O O   . THR A 1 313 ? 4.332   73.310  58.434 1.00 89.99  ? 321 THR A O   1 
ATOM   2416  C CB  . THR A 1 313 ? 6.118   74.636  55.964 1.00 119.96 ? 321 THR A CB  1 
ATOM   2417  O OG1 . THR A 1 313 ? 5.142   75.550  56.472 1.00 113.93 ? 321 THR A OG1 1 
ATOM   2418  C CG2 . THR A 1 313 ? 6.193   74.683  54.445 1.00 118.50 ? 321 THR A CG2 1 
ATOM   2419  N N   . LEU A 1 314 ? 6.549   73.374  58.810 1.00 65.17  ? 322 LEU A N   1 
ATOM   2420  C CA  . LEU A 1 314 ? 6.338   73.383  60.250 1.00 69.84  ? 322 LEU A CA  1 
ATOM   2421  C C   . LEU A 1 314 ? 5.788   74.744  60.630 1.00 81.29  ? 322 LEU A C   1 
ATOM   2422  O O   . LEU A 1 314 ? 4.972   74.797  61.558 1.00 79.74  ? 322 LEU A O   1 
ATOM   2423  C CB  . LEU A 1 314 ? 7.520   72.944  61.114 1.00 81.81  ? 322 LEU A CB  1 
ATOM   2424  C CG  . LEU A 1 314 ? 7.675   73.607  62.491 1.00 70.06  ? 322 LEU A CG  1 
ATOM   2425  C CD1 . LEU A 1 314 ? 6.867   73.013  63.616 1.00 53.61  ? 322 LEU A CD1 1 
ATOM   2426  C CD2 . LEU A 1 314 ? 9.122   73.700  62.860 1.00 56.35  ? 322 LEU A CD2 1 
ATOM   2427  N N   . GLU A 1 315 ? 6.184   75.792  59.871 1.00 72.72  ? 323 GLU A N   1 
ATOM   2428  C CA  . GLU A 1 315 ? 5.664   77.136  60.113 1.00 99.54  ? 323 GLU A CA  1 
ATOM   2429  C C   . GLU A 1 315 ? 4.137   77.158  60.032 1.00 105.09 ? 323 GLU A C   1 
ATOM   2430  O O   . GLU A 1 315 ? 3.508   77.830  60.848 1.00 96.24  ? 323 GLU A O   1 
ATOM   2431  C CB  . GLU A 1 315 ? 6.138   78.208  59.139 1.00 94.33  ? 323 GLU A CB  1 
ATOM   2432  C CG  . GLU A 1 315 ? 7.615   78.542  59.318 1.00 86.91  ? 323 GLU A CG  1 
ATOM   2433  C CD  . GLU A 1 315 ? 8.479   77.378  58.886 1.00 93.51  ? 323 GLU A CD  1 
ATOM   2434  O OE1 . GLU A 1 315 ? 8.023   76.398  58.243 1.00 115.24 ? 323 GLU A OE1 1 
ATOM   2435  O OE2 . GLU A 1 315 ? 9.683   77.543  59.138 1.00 78.37  ? 323 GLU A OE2 1 
ATOM   2436  N N   . PHE A 1 316 ? 3.590   76.466  59.014 1.00 79.34  ? 324 PHE A N   1 
ATOM   2437  C CA  . PHE A 1 316 ? 2.150   76.262  58.883 1.00 76.49  ? 324 PHE A CA  1 
ATOM   2438  C C   . PHE A 1 316 ? 1.561   75.628  60.158 1.00 82.16  ? 324 PHE A C   1 
ATOM   2439  O O   . PHE A 1 316 ? 0.607   76.186  60.704 1.00 76.16  ? 324 PHE A O   1 
ATOM   2440  C CB  . PHE A 1 316 ? 1.771   75.460  57.631 1.00 61.61  ? 324 PHE A CB  1 
ATOM   2441  C CG  . PHE A 1 316 ? 0.289   75.424  57.260 1.00 70.53  ? 324 PHE A CG  1 
ATOM   2442  C CD1 . PHE A 1 316 ? -0.248  76.394  56.427 1.00 99.20  ? 324 PHE A CD1 1 
ATOM   2443  C CD2 . PHE A 1 316 ? -0.554  74.375  57.642 1.00 87.06  ? 324 PHE A CD2 1 
ATOM   2444  C CE1 . PHE A 1 316 ? -1.583  76.331  56.035 1.00 119.16 ? 324 PHE A CE1 1 
ATOM   2445  C CE2 . PHE A 1 316 ? -1.909  74.345  57.297 1.00 86.27  ? 324 PHE A CE2 1 
ATOM   2446  C CZ  . PHE A 1 316 ? -2.430  75.336  56.507 1.00 87.77  ? 324 PHE A CZ  1 
ATOM   2447  N N   . LYS A 1 317 ? 2.112   74.471  60.616 1.00 69.90  ? 325 LYS A N   1 
ATOM   2448  C CA  . LYS A 1 317 ? 1.605   73.746  61.780 1.00 84.62  ? 325 LYS A CA  1 
ATOM   2449  C C   . LYS A 1 317 ? 1.571   74.700  62.994 1.00 88.57  ? 325 LYS A C   1 
ATOM   2450  O O   . LYS A 1 317 ? 0.619   74.737  63.810 1.00 46.95  ? 325 LYS A O   1 
ATOM   2451  C CB  . LYS A 1 317 ? 2.466   72.485  61.927 1.00 77.13  ? 325 LYS A CB  1 
ATOM   2452  C CG  . LYS A 1 317 ? 1.982   71.304  62.792 1.00 63.99  ? 325 LYS A CG  1 
ATOM   2453  C CD  . LYS A 1 317 ? 2.900   70.055  62.643 1.00 55.92  ? 325 LYS A CD  1 
ATOM   2454  C CE  . LYS A 1 317 ? 3.055   69.065  61.442 1.00 53.70  ? 325 LYS A CE  1 
ATOM   2455  N NZ  . LYS A 1 317 ? 4.192   69.134  60.483 1.00 44.02  ? 325 LYS A NZ  1 
ATOM   2456  N N   . VAL A 1 318 ? 2.611   75.548  63.058 1.00 86.53  ? 326 VAL A N   1 
ATOM   2457  C CA  . VAL A 1 318 ? 2.704   76.519  64.133 1.00 94.61  ? 326 VAL A CA  1 
ATOM   2458  C C   . VAL A 1 318 ? 1.572   77.548  64.037 1.00 110.10 ? 326 VAL A C   1 
ATOM   2459  O O   . VAL A 1 318 ? 0.831   77.790  64.998 1.00 97.87  ? 326 VAL A O   1 
ATOM   2460  C CB  . VAL A 1 318 ? 4.099   77.152  64.008 1.00 88.03  ? 326 VAL A CB  1 
ATOM   2461  C CG1 . VAL A 1 318 ? 4.130   78.587  64.534 1.00 127.21 ? 326 VAL A CG1 1 
ATOM   2462  C CG2 . VAL A 1 318 ? 5.118   76.268  64.728 1.00 68.42  ? 326 VAL A CG2 1 
ATOM   2463  N N   . TYR A 1 319 ? 1.452   78.118  62.832 1.00 112.31 ? 327 TYR A N   1 
ATOM   2464  C CA  . TYR A 1 319 ? 0.403   79.060  62.476 1.00 96.34  ? 327 TYR A CA  1 
ATOM   2465  C C   . TYR A 1 319 ? -0.962  78.533  62.933 1.00 77.81  ? 327 TYR A C   1 
ATOM   2466  O O   . TYR A 1 319 ? -1.701  79.230  63.612 1.00 60.84  ? 327 TYR A O   1 
ATOM   2467  C CB  . TYR A 1 319 ? 0.409   79.347  60.965 1.00 110.44 ? 327 TYR A CB  1 
ATOM   2468  C CG  . TYR A 1 319 ? -0.878  80.014  60.489 1.00 120.02 ? 327 TYR A CG  1 
ATOM   2469  C CD1 . TYR A 1 319 ? -1.187  81.330  60.848 1.00 116.11 ? 327 TYR A CD1 1 
ATOM   2470  C CD2 . TYR A 1 319 ? -1.777  79.348  59.666 1.00 101.10 ? 327 TYR A CD2 1 
ATOM   2471  C CE1 . TYR A 1 319 ? -2.353  81.945  60.424 1.00 104.22 ? 327 TYR A CE1 1 
ATOM   2472  C CE2 . TYR A 1 319 ? -2.935  79.966  59.217 1.00 95.00  ? 327 TYR A CE2 1 
ATOM   2473  C CZ  . TYR A 1 319 ? -3.245  81.254  59.618 1.00 99.17  ? 327 TYR A CZ  1 
ATOM   2474  O OH  . TYR A 1 319 ? -4.408  81.825  59.174 1.00 89.97  ? 327 TYR A OH  1 
ATOM   2475  N N   . GLN A 1 320 ? -1.293  77.292  62.573 1.00 64.13  ? 328 GLN A N   1 
ATOM   2476  C CA  . GLN A 1 320 ? -2.564  76.703  62.967 1.00 86.50  ? 328 GLN A CA  1 
ATOM   2477  C C   . GLN A 1 320 ? -2.707  76.645  64.490 1.00 86.62  ? 328 GLN A C   1 
ATOM   2478  O O   . GLN A 1 320 ? -3.774  76.959  65.046 1.00 79.48  ? 328 GLN A O   1 
ATOM   2479  C CB  . GLN A 1 320 ? -2.836  75.378  62.244 1.00 83.22  ? 328 GLN A CB  1 
ATOM   2480  C CG  . GLN A 1 320 ? -2.962  75.524  60.724 1.00 87.79  ? 328 GLN A CG  1 
ATOM   2481  C CD  . GLN A 1 320 ? -4.049  76.477  60.237 1.00 97.94  ? 328 GLN A CD  1 
ATOM   2482  O OE1 . GLN A 1 320 ? -4.947  76.898  60.971 1.00 126.33 ? 328 GLN A OE1 1 
ATOM   2483  N NE2 . GLN A 1 320 ? -3.993  76.820  58.962 1.00 97.10  ? 328 GLN A NE2 1 
ATOM   2484  N N   . HIS A 1 321 ? -1.640  76.208  65.177 1.00 85.44  ? 329 HIS A N   1 
ATOM   2485  C CA  . HIS A 1 321 ? -1.756  76.153  66.630 1.00 86.51  ? 329 HIS A CA  1 
ATOM   2486  C C   . HIS A 1 321 ? -2.025  77.564  67.138 1.00 68.32  ? 329 HIS A C   1 
ATOM   2487  O O   . HIS A 1 321 ? -2.929  77.770  67.934 1.00 64.60  ? 329 HIS A O   1 
ATOM   2488  C CB  . HIS A 1 321 ? -0.695  75.305  67.354 1.00 84.54  ? 329 HIS A CB  1 
ATOM   2489  C CG  . HIS A 1 321 ? -0.954  73.823  67.390 1.00 117.36 ? 329 HIS A CG  1 
ATOM   2490  N ND1 . HIS A 1 321 ? -1.770  73.205  68.321 1.00 159.38 ? 329 HIS A ND1 1 
ATOM   2491  C CD2 . HIS A 1 321 ? -0.460  72.820  66.631 1.00 133.35 ? 329 HIS A CD2 1 
ATOM   2492  C CE1 . HIS A 1 321 ? -1.788  71.887  68.100 1.00 162.64 ? 329 HIS A CE1 1 
ATOM   2493  N NE2 . HIS A 1 321 ? -0.979  71.624  67.090 1.00 127.92 ? 329 HIS A NE2 1 
ATOM   2494  N N   . GLN A 1 322 ? -1.291  78.534  66.602 1.00 69.33  ? 330 GLN A N   1 
ATOM   2495  C CA  . GLN A 1 322 ? -1.483  79.925  66.978 1.00 81.00  ? 330 GLN A CA  1 
ATOM   2496  C C   . GLN A 1 322 ? -2.912  80.378  66.680 1.00 77.40  ? 330 GLN A C   1 
ATOM   2497  O O   . GLN A 1 322 ? -3.540  81.033  67.511 1.00 82.05  ? 330 GLN A O   1 
ATOM   2498  C CB  . GLN A 1 322 ? -0.497  80.819  66.237 1.00 92.74  ? 330 GLN A CB  1 
ATOM   2499  C CG  . GLN A 1 322 ? -0.450  82.227  66.808 1.00 91.15  ? 330 GLN A CG  1 
ATOM   2500  C CD  . GLN A 1 322 ? -0.036  82.244  68.267 1.00 98.98  ? 330 GLN A CD  1 
ATOM   2501  O OE1 . GLN A 1 322 ? 0.936   81.579  68.646 1.00 70.96  ? 330 GLN A OE1 1 
ATOM   2502  N NE2 . GLN A 1 322 ? -0.732  83.031  69.089 1.00 114.12 ? 330 GLN A NE2 1 
ATOM   2503  N N   . VAL A 1 323 ? -3.427  79.995  65.509 1.00 67.50  ? 331 VAL A N   1 
ATOM   2504  C CA  . VAL A 1 323 ? -4.774  80.391  65.124 1.00 73.37  ? 331 VAL A CA  1 
ATOM   2505  C C   . VAL A 1 323 ? -5.752  79.981  66.229 1.00 80.37  ? 331 VAL A C   1 
ATOM   2506  O O   . VAL A 1 323 ? -6.622  80.758  66.638 1.00 68.86  ? 331 VAL A O   1 
ATOM   2507  C CB  . VAL A 1 323 ? -5.196  79.742  63.798 1.00 59.72  ? 331 VAL A CB  1 
ATOM   2508  C CG1 . VAL A 1 323 ? -6.709  79.537  63.795 1.00 58.84  ? 331 VAL A CG1 1 
ATOM   2509  C CG2 . VAL A 1 323 ? -4.689  80.529  62.573 1.00 82.95  ? 331 VAL A CG2 1 
ATOM   2510  N N   . VAL A 1 324 ? -5.586  78.755  66.730 1.00 66.77  ? 332 VAL A N   1 
ATOM   2511  C CA  . VAL A 1 324 ? -6.512  78.287  67.745 1.00 70.20  ? 332 VAL A CA  1 
ATOM   2512  C C   . VAL A 1 324 ? -6.254  78.978  69.088 1.00 87.40  ? 332 VAL A C   1 
ATOM   2513  O O   . VAL A 1 324 ? -7.198  79.228  69.858 1.00 103.75 ? 332 VAL A O   1 
ATOM   2514  C CB  . VAL A 1 324 ? -6.602  76.764  67.953 1.00 60.28  ? 332 VAL A CB  1 
ATOM   2515  C CG1 . VAL A 1 324 ? -7.709  76.483  68.958 1.00 42.14  ? 332 VAL A CG1 1 
ATOM   2516  C CG2 . VAL A 1 324 ? -6.833  75.975  66.681 1.00 55.87  ? 332 VAL A CG2 1 
ATOM   2517  N N   . ALA A 1 325 ? -4.971  79.237  69.377 1.00 82.45  ? 333 ALA A N   1 
ATOM   2518  C CA  . ALA A 1 325 ? -4.587  79.938  70.589 1.00 92.66  ? 333 ALA A CA  1 
ATOM   2519  C C   . ALA A 1 325 ? -5.265  81.305  70.618 1.00 88.50  ? 333 ALA A C   1 
ATOM   2520  O O   . ALA A 1 325 ? -5.892  81.686  71.613 1.00 93.93  ? 333 ALA A O   1 
ATOM   2521  C CB  . ALA A 1 325 ? -3.091  80.098  70.623 1.00 85.48  ? 333 ALA A CB  1 
ATOM   2522  N N   . ASN A 1 326 ? -5.143  82.006  69.495 1.00 60.22  ? 334 ASN A N   1 
ATOM   2523  C CA  . ASN A 1 326 ? -5.672  83.348  69.351 1.00 83.79  ? 334 ASN A CA  1 
ATOM   2524  C C   . ASN A 1 326 ? -7.184  83.330  69.574 1.00 99.12  ? 334 ASN A C   1 
ATOM   2525  O O   . ASN A 1 326 ? -7.724  84.169  70.295 1.00 120.35 ? 334 ASN A O   1 
ATOM   2526  C CB  . ASN A 1 326 ? -5.253  83.951  68.015 1.00 92.03  ? 334 ASN A CB  1 
ATOM   2527  C CG  . ASN A 1 326 ? -3.781  84.304  67.934 1.00 92.75  ? 334 ASN A CG  1 
ATOM   2528  O OD1 . ASN A 1 326 ? -3.098  84.460  68.969 1.00 83.04  ? 334 ASN A OD1 1 
ATOM   2529  N ND2 . ASN A 1 326 ? -3.260  84.426  66.719 1.00 79.94  ? 334 ASN A ND2 1 
ATOM   2530  N N   . CYS A 1 327 ? -7.863  82.359  68.964 1.00 95.67  ? 335 CYS A N   1 
ATOM   2531  C CA  . CYS A 1 327 ? -9.297  82.239  69.125 1.00 111.99 ? 335 CYS A CA  1 
ATOM   2532  C C   . CYS A 1 327 ? -9.647  82.093  70.605 1.00 127.76 ? 335 CYS A C   1 
ATOM   2533  O O   . CYS A 1 327 ? -10.559 82.768  71.104 1.00 137.83 ? 335 CYS A O   1 
ATOM   2534  C CB  . CYS A 1 327 ? -9.820  81.074  68.300 1.00 111.96 ? 335 CYS A CB  1 
ATOM   2535  S SG  . CYS A 1 327 ? -11.618 80.879  68.483 1.00 100.55 ? 335 CYS A SG  1 
ATOM   2536  N N   . ARG A 1 328 ? -8.895  81.232  71.312 1.00 116.16 ? 336 ARG A N   1 
ATOM   2537  C CA  . ARG A 1 328 ? -9.166  81.011  72.719 1.00 110.72 ? 336 ARG A CA  1 
ATOM   2538  C C   . ARG A 1 328 ? -8.974  82.324  73.463 1.00 98.67  ? 336 ARG A C   1 
ATOM   2539  O O   . ARG A 1 328 ? -9.854  82.674  74.247 1.00 70.48  ? 336 ARG A O   1 
ATOM   2540  C CB  . ARG A 1 328 ? -8.344  79.905  73.381 1.00 102.18 ? 336 ARG A CB  1 
ATOM   2541  C CG  . ARG A 1 328 ? -8.652  78.520  72.853 1.00 96.17  ? 336 ARG A CG  1 
ATOM   2542  C CD  . ARG A 1 328 ? -7.828  77.550  73.702 1.00 101.57 ? 336 ARG A CD  1 
ATOM   2543  N NE  . ARG A 1 328 ? -7.421  76.391  72.895 1.00 109.65 ? 336 ARG A NE  1 
ATOM   2544  C CZ  . ARG A 1 328 ? -8.203  75.536  72.233 1.00 118.29 ? 336 ARG A CZ  1 
ATOM   2545  N NH1 . ARG A 1 328 ? -9.507  75.738  72.086 1.00 85.12  ? 336 ARG A NH1 1 
ATOM   2546  N NH2 . ARG A 1 328 ? -7.654  74.472  71.669 1.00 164.36 ? 336 ARG A NH2 1 
ATOM   2547  N N   . ALA A 1 329 ? -7.874  83.045  73.157 1.00 76.35  ? 337 ALA A N   1 
ATOM   2548  C CA  . ALA A 1 329 ? -7.544  84.293  73.832 1.00 96.70  ? 337 ALA A CA  1 
ATOM   2549  C C   . ALA A 1 329 ? -8.689  85.286  73.695 1.00 109.03 ? 337 ALA A C   1 
ATOM   2550  O O   . ALA A 1 329 ? -9.195  85.821  74.700 1.00 130.35 ? 337 ALA A O   1 
ATOM   2551  C CB  . ALA A 1 329 ? -6.259  84.878  73.308 1.00 71.03  ? 337 ALA A CB  1 
ATOM   2552  N N   . LEU A 1 330 ? -9.074  85.491  72.428 1.00 98.51  ? 338 LEU A N   1 
ATOM   2553  C CA  . LEU A 1 330 ? -10.181 86.378  72.097 1.00 101.68 ? 338 LEU A CA  1 
ATOM   2554  C C   . LEU A 1 330 ? -11.467 85.952  72.825 1.00 106.37 ? 338 LEU A C   1 
ATOM   2555  O O   . LEU A 1 330 ? -12.115 86.787  73.495 1.00 112.58 ? 338 LEU A O   1 
ATOM   2556  C CB  . LEU A 1 330 ? -10.350 86.412  70.586 1.00 89.16  ? 338 LEU A CB  1 
ATOM   2557  C CG  . LEU A 1 330 ? -11.518 87.257  70.087 1.00 74.27  ? 338 LEU A CG  1 
ATOM   2558  C CD1 . LEU A 1 330 ? -11.272 88.718  70.398 1.00 89.45  ? 338 LEU A CD1 1 
ATOM   2559  C CD2 . LEU A 1 330 ? -11.633 87.106  68.574 1.00 72.64  ? 338 LEU A CD2 1 
ATOM   2560  N N   . SER A 1 331 ? -11.778 84.642  72.758 1.00 83.52  ? 339 SER A N   1 
ATOM   2561  C CA  . SER A 1 331 ? -12.966 84.119  73.414 1.00 93.43  ? 339 SER A CA  1 
ATOM   2562  C C   . SER A 1 331 ? -12.889 84.381  74.913 1.00 110.06 ? 339 SER A C   1 
ATOM   2563  O O   . SER A 1 331 ? -13.822 84.905  75.517 1.00 114.90 ? 339 SER A O   1 
ATOM   2564  C CB  . SER A 1 331 ? -13.140 82.659  73.222 1.00 115.57 ? 339 SER A CB  1 
ATOM   2565  O OG  . SER A 1 331 ? -14.375 82.275  73.844 1.00 119.24 ? 339 SER A OG  1 
ATOM   2566  N N   . GLU A 1 332 ? -11.770 83.990  75.523 1.00 96.52  ? 340 GLU A N   1 
ATOM   2567  C CA  . GLU A 1 332 ? -11.668 84.075  76.969 1.00 92.82  ? 340 GLU A CA  1 
ATOM   2568  C C   . GLU A 1 332 ? -11.862 85.535  77.365 1.00 99.89  ? 340 GLU A C   1 
ATOM   2569  O O   . GLU A 1 332 ? -12.634 85.805  78.287 1.00 93.80  ? 340 GLU A O   1 
ATOM   2570  C CB  . GLU A 1 332 ? -10.450 83.270  77.424 1.00 91.44  ? 340 GLU A CB  1 
ATOM   2571  C CG  . GLU A 1 332 ? -9.911  83.669  78.794 1.00 99.15  ? 340 GLU A CG  1 
ATOM   2572  C CD  . GLU A 1 332 ? -8.792  82.820  79.377 1.00 109.92 ? 340 GLU A CD  1 
ATOM   2573  O OE1 . GLU A 1 332 ? -7.751  82.599  78.700 1.00 109.46 ? 340 GLU A OE1 1 
ATOM   2574  O OE2 . GLU A 1 332 ? -8.961  82.361  80.530 1.00 99.83  ? 340 GLU A OE2 1 
ATOM   2575  N N   . ALA A 1 333 ? -11.188 86.455  76.650 1.00 94.61  ? 341 ALA A N   1 
ATOM   2576  C CA  . ALA A 1 333 ? -11.237 87.876  76.972 1.00 86.97  ? 341 ALA A CA  1 
ATOM   2577  C C   . ALA A 1 333 ? -12.680 88.397  76.978 1.00 106.75 ? 341 ALA A C   1 
ATOM   2578  O O   . ALA A 1 333 ? -13.120 89.061  77.929 1.00 94.22  ? 341 ALA A O   1 
ATOM   2579  C CB  . ALA A 1 333 ? -10.361 88.652  76.009 1.00 75.66  ? 341 ALA A CB  1 
ATOM   2580  N N   . LEU A 1 334 ? -13.424 88.084  75.908 1.00 98.42  ? 342 LEU A N   1 
ATOM   2581  C CA  . LEU A 1 334 ? -14.791 88.570  75.809 1.00 98.37  ? 342 LEU A CA  1 
ATOM   2582  C C   . LEU A 1 334 ? -15.647 87.951  76.922 1.00 93.95  ? 342 LEU A C   1 
ATOM   2583  O O   . LEU A 1 334 ? -16.524 88.605  77.515 1.00 71.71  ? 342 LEU A O   1 
ATOM   2584  C CB  . LEU A 1 334 ? -15.359 88.313  74.418 1.00 73.72  ? 342 LEU A CB  1 
ATOM   2585  C CG  . LEU A 1 334 ? -14.616 89.100  73.340 1.00 76.29  ? 342 LEU A CG  1 
ATOM   2586  C CD1 . LEU A 1 334 ? -14.877 88.585  71.932 1.00 115.18 ? 342 LEU A CD1 1 
ATOM   2587  C CD2 . LEU A 1 334 ? -15.006 90.547  73.450 1.00 66.83  ? 342 LEU A CD2 1 
ATOM   2588  N N   . THR A 1 335 ? -15.361 86.677  77.206 1.00 81.95  ? 343 THR A N   1 
ATOM   2589  C CA  . THR A 1 335 ? -16.175 85.953  78.166 1.00 94.41  ? 343 THR A CA  1 
ATOM   2590  C C   . THR A 1 335 ? -15.974 86.588  79.519 1.00 94.46  ? 343 THR A C   1 
ATOM   2591  O O   . THR A 1 335 ? -16.962 86.728  80.230 1.00 83.36  ? 343 THR A O   1 
ATOM   2592  C CB  . THR A 1 335 ? -15.851 84.465  78.281 1.00 86.60  ? 343 THR A CB  1 
ATOM   2593  O OG1 . THR A 1 335 ? -15.970 83.921  76.975 1.00 97.51  ? 343 THR A OG1 1 
ATOM   2594  C CG2 . THR A 1 335 ? -16.785 83.785  79.262 1.00 59.50  ? 343 THR A CG2 1 
ATOM   2595  N N   . GLU A 1 336 ? -14.704 86.906  79.844 1.00 89.65  ? 344 GLU A N   1 
ATOM   2596  C CA  . GLU A 1 336 ? -14.325 87.570  81.083 1.00 88.01  ? 344 GLU A CA  1 
ATOM   2597  C C   . GLU A 1 336 ? -15.062 88.897  81.189 1.00 77.28  ? 344 GLU A C   1 
ATOM   2598  O O   . GLU A 1 336 ? -15.569 89.225  82.284 1.00 64.36  ? 344 GLU A O   1 
ATOM   2599  C CB  . GLU A 1 336 ? -12.811 87.765  81.144 1.00 95.98  ? 344 GLU A CB  1 
ATOM   2600  C CG  . GLU A 1 336 ? -12.073 86.447  81.326 1.00 102.73 ? 344 GLU A CG  1 
ATOM   2601  C CD  . GLU A 1 336 ? -10.605 86.644  81.550 1.00 99.25  ? 344 GLU A CD  1 
ATOM   2602  O OE1 . GLU A 1 336 ? -10.050 87.738  81.245 1.00 78.89  ? 344 GLU A OE1 1 
ATOM   2603  O OE2 . GLU A 1 336 ? -10.078 85.664  82.121 1.00 101.77 ? 344 GLU A OE2 1 
ATOM   2604  N N   . LEU A 1 337 ? -15.121 89.604  80.034 1.00 58.14  ? 345 LEU A N   1 
ATOM   2605  C CA  . LEU A 1 337 ? -15.802 90.889  79.958 1.00 66.93  ? 345 LEU A CA  1 
ATOM   2606  C C   . LEU A 1 337 ? -17.323 90.723  80.042 1.00 78.06  ? 345 LEU A C   1 
ATOM   2607  O O   . LEU A 1 337 ? -18.038 91.710  79.926 1.00 84.76  ? 345 LEU A O   1 
ATOM   2608  C CB  . LEU A 1 337 ? -15.430 91.577  78.647 1.00 57.03  ? 345 LEU A CB  1 
ATOM   2609  C CG  . LEU A 1 337 ? -14.089 92.287  78.606 1.00 67.56  ? 345 LEU A CG  1 
ATOM   2610  C CD1 . LEU A 1 337 ? -13.702 92.449  77.138 1.00 86.68  ? 345 LEU A CD1 1 
ATOM   2611  C CD2 . LEU A 1 337 ? -14.246 93.627  79.268 1.00 67.19  ? 345 LEU A CD2 1 
ATOM   2612  N N   . GLY A 1 338 ? -17.811 89.490  80.225 1.00 72.08  ? 346 GLY A N   1 
ATOM   2613  C CA  . GLY A 1 338 ? -19.226 89.231  80.388 1.00 77.96  ? 346 GLY A CA  1 
ATOM   2614  C C   . GLY A 1 338 ? -19.984 88.913  79.098 1.00 101.49 ? 346 GLY A C   1 
ATOM   2615  O O   . GLY A 1 338 ? -21.200 88.726  79.194 1.00 97.51  ? 346 GLY A O   1 
ATOM   2616  N N   . TYR A 1 339 ? -19.305 88.823  77.932 1.00 89.77  ? 347 TYR A N   1 
ATOM   2617  C CA  . TYR A 1 339 ? -20.024 88.533  76.696 1.00 88.20  ? 347 TYR A CA  1 
ATOM   2618  C C   . TYR A 1 339 ? -20.348 87.037  76.583 1.00 113.71 ? 347 TYR A C   1 
ATOM   2619  O O   . TYR A 1 339 ? -19.562 86.209  77.053 1.00 119.54 ? 347 TYR A O   1 
ATOM   2620  C CB  . TYR A 1 339 ? -19.146 88.917  75.519 1.00 76.89  ? 347 TYR A CB  1 
ATOM   2621  C CG  . TYR A 1 339 ? -18.974 90.394  75.208 1.00 83.22  ? 347 TYR A CG  1 
ATOM   2622  C CD1 . TYR A 1 339 ? -19.870 91.053  74.378 1.00 89.72  ? 347 TYR A CD1 1 
ATOM   2623  C CD2 . TYR A 1 339 ? -17.855 91.087  75.629 1.00 98.87  ? 347 TYR A CD2 1 
ATOM   2624  C CE1 . TYR A 1 339 ? -19.683 92.373  73.995 1.00 86.62  ? 347 TYR A CE1 1 
ATOM   2625  C CE2 . TYR A 1 339 ? -17.652 92.419  75.255 1.00 110.81 ? 347 TYR A CE2 1 
ATOM   2626  C CZ  . TYR A 1 339 ? -18.569 93.065  74.434 1.00 104.02 ? 347 TYR A CZ  1 
ATOM   2627  O OH  . TYR A 1 339 ? -18.424 94.349  73.972 1.00 90.70  ? 347 TYR A OH  1 
ATOM   2628  N N   . LYS A 1 340 ? -21.527 86.703  76.009 1.00 81.44  ? 348 LYS A N   1 
ATOM   2629  C CA  . LYS A 1 340 ? -21.979 85.312  75.942 1.00 83.18  ? 348 LYS A CA  1 
ATOM   2630  C C   . LYS A 1 340 ? -21.491 84.633  74.664 1.00 107.81 ? 348 LYS A C   1 
ATOM   2631  O O   . LYS A 1 340 ? -21.732 85.126  73.557 1.00 143.92 ? 348 LYS A O   1 
ATOM   2632  C CB  . LYS A 1 340 ? -23.501 85.366  75.895 1.00 72.67  ? 348 LYS A CB  1 
ATOM   2633  C CG  . LYS A 1 340 ? -24.366 84.126  75.849 1.00 92.87  ? 348 LYS A CG  1 
ATOM   2634  C CD  . LYS A 1 340 ? -25.783 84.727  76.067 1.00 123.11 ? 348 LYS A CD  1 
ATOM   2635  C CE  . LYS A 1 340 ? -27.106 84.177  76.595 1.00 107.43 ? 348 LYS A CE  1 
ATOM   2636  N NZ  . LYS A 1 340 ? -27.548 82.958  75.915 1.00 117.79 ? 348 LYS A NZ  1 
ATOM   2637  N N   . ILE A 1 341 ? -20.727 83.545  74.809 1.00 86.35  ? 349 ILE A N   1 
ATOM   2638  C CA  . ILE A 1 341 ? -20.092 82.914  73.655 1.00 73.50  ? 349 ILE A CA  1 
ATOM   2639  C C   . ILE A 1 341 ? -20.844 81.620  73.390 1.00 95.92  ? 349 ILE A C   1 
ATOM   2640  O O   . ILE A 1 341 ? -20.854 80.763  74.254 1.00 125.52 ? 349 ILE A O   1 
ATOM   2641  C CB  . ILE A 1 341 ? -18.588 82.636  73.880 1.00 70.13  ? 349 ILE A CB  1 
ATOM   2642  C CG1 . ILE A 1 341 ? -17.801 83.930  74.031 1.00 79.17  ? 349 ILE A CG1 1 
ATOM   2643  C CG2 . ILE A 1 341 ? -17.974 81.804  72.747 1.00 102.21 ? 349 ILE A CG2 1 
ATOM   2644  C CD1 . ILE A 1 341 ? -17.978 84.916  72.891 1.00 55.63  ? 349 ILE A CD1 1 
ATOM   2645  N N   . VAL A 1 342 ? -21.462 81.478  72.210 1.00 102.98 ? 350 VAL A N   1 
ATOM   2646  C CA  . VAL A 1 342 ? -22.276 80.311  71.914 1.00 92.30  ? 350 VAL A CA  1 
ATOM   2647  C C   . VAL A 1 342 ? -21.423 79.066  72.084 1.00 100.74 ? 350 VAL A C   1 
ATOM   2648  O O   . VAL A 1 342 ? -20.300 79.013  71.585 1.00 110.23 ? 350 VAL A O   1 
ATOM   2649  C CB  . VAL A 1 342 ? -22.924 80.332  70.524 1.00 106.03 ? 350 VAL A CB  1 
ATOM   2650  C CG1 . VAL A 1 342 ? -23.624 79.011  70.231 1.00 124.76 ? 350 VAL A CG1 1 
ATOM   2651  C CG2 . VAL A 1 342 ? -23.935 81.467  70.395 1.00 88.84  ? 350 VAL A CG2 1 
ATOM   2652  N N   . THR A 1 343 ? -22.009 78.080  72.775 1.00 93.12  ? 351 THR A N   1 
ATOM   2653  C CA  . THR A 1 343 ? -21.328 76.830  73.097 1.00 109.01 ? 351 THR A CA  1 
ATOM   2654  C C   . THR A 1 343 ? -20.295 77.019  74.215 1.00 115.38 ? 351 THR A C   1 
ATOM   2655  O O   . THR A 1 343 ? -19.702 76.045  74.677 1.00 134.20 ? 351 THR A O   1 
ATOM   2656  C CB  . THR A 1 343 ? -20.671 76.192  71.869 1.00 109.17 ? 351 THR A CB  1 
ATOM   2657  O OG1 . THR A 1 343 ? -20.439 74.849  72.290 1.00 82.46  ? 351 THR A OG1 1 
ATOM   2658  C CG2 . THR A 1 343 ? -19.360 76.845  71.449 1.00 87.70  ? 351 THR A CG2 1 
ATOM   2659  N N   . GLY A 1 344 ? -20.069 78.259  74.666 1.00 90.05  ? 352 GLY A N   1 
ATOM   2660  C CA  . GLY A 1 344 ? -19.196 78.475  75.808 1.00 77.14  ? 352 GLY A CA  1 
ATOM   2661  C C   . GLY A 1 344 ? -17.800 78.887  75.357 1.00 91.74  ? 352 GLY A C   1 
ATOM   2662  O O   . GLY A 1 344 ? -17.022 79.456  76.089 1.00 123.72 ? 352 GLY A O   1 
ATOM   2663  N N   . GLY A 1 345 ? -17.459 78.601  74.112 1.00 104.81 ? 353 GLY A N   1 
ATOM   2664  C CA  . GLY A 1 345 ? -16.089 78.824  73.687 1.00 103.33 ? 353 GLY A CA  1 
ATOM   2665  C C   . GLY A 1 345 ? -15.847 78.171  72.329 1.00 104.36 ? 353 GLY A C   1 
ATOM   2666  O O   . GLY A 1 345 ? -16.783 78.021  71.545 1.00 116.58 ? 353 GLY A O   1 
ATOM   2667  N N   . SER A 1 346 ? -14.600 77.759  72.087 1.00 85.04  ? 354 SER A N   1 
ATOM   2668  C CA  . SER A 1 346 ? -14.179 77.314  70.774 1.00 95.78  ? 354 SER A CA  1 
ATOM   2669  C C   . SER A 1 346 ? -13.063 76.268  70.837 1.00 94.77  ? 354 SER A C   1 
ATOM   2670  O O   . SER A 1 346 ? -12.146 76.357  71.640 1.00 111.56 ? 354 SER A O   1 
ATOM   2671  C CB  . SER A 1 346 ? -13.789 78.480  69.887 1.00 82.80  ? 354 SER A CB  1 
ATOM   2672  O OG  . SER A 1 346 ? -13.461 77.999  68.586 1.00 64.84  ? 354 SER A OG  1 
ATOM   2673  N N   . ASP A 1 347 ? -13.155 75.282  69.940 1.00 87.97  ? 355 ASP A N   1 
ATOM   2674  C CA  . ASP A 1 347 ? -12.126 74.292  69.692 1.00 83.68  ? 355 ASP A CA  1 
ATOM   2675  C C   . ASP A 1 347 ? -11.356 74.671  68.430 1.00 94.16  ? 355 ASP A C   1 
ATOM   2676  O O   . ASP A 1 347 ? -10.401 73.972  68.096 1.00 131.72 ? 355 ASP A O   1 
ATOM   2677  C CB  . ASP A 1 347 ? -12.748 72.917  69.505 1.00 77.05  ? 355 ASP A CB  1 
ATOM   2678  C CG  . ASP A 1 347 ? -13.620 72.459  70.664 1.00 97.65  ? 355 ASP A CG  1 
ATOM   2679  O OD1 . ASP A 1 347 ? -13.283 72.858  71.804 1.00 99.55  ? 355 ASP A OD1 1 
ATOM   2680  O OD2 . ASP A 1 347 ? -14.607 71.696  70.417 1.00 107.06 ? 355 ASP A OD2 1 
ATOM   2681  N N   . ASN A 1 348 ? -11.758 75.761  67.745 1.00 77.72  ? 356 ASN A N   1 
ATOM   2682  C CA  . ASN A 1 348 ? -11.279 76.060  66.388 1.00 88.49  ? 356 ASN A CA  1 
ATOM   2683  C C   . ASN A 1 348 ? -10.927 77.544  66.260 1.00 100.20 ? 356 ASN A C   1 
ATOM   2684  O O   . ASN A 1 348 ? -10.555 78.196  67.239 1.00 131.45 ? 356 ASN A O   1 
ATOM   2685  C CB  . ASN A 1 348 ? -12.251 75.620  65.282 1.00 77.49  ? 356 ASN A CB  1 
ATOM   2686  C CG  . ASN A 1 348 ? -13.683 76.105  65.502 1.00 94.29  ? 356 ASN A CG  1 
ATOM   2687  O OD1 . ASN A 1 348 ? -13.923 77.290  65.762 1.00 91.91  ? 356 ASN A OD1 1 
ATOM   2688  N ND2 . ASN A 1 348 ? -14.677 75.219  65.482 1.00 74.11  ? 356 ASN A ND2 1 
ATOM   2689  N N   . HIS A 1 349 ? -11.115 78.081  65.052 1.00 79.90  ? 357 HIS A N   1 
ATOM   2690  C CA  . HIS A 1 349 ? -10.634 79.408  64.697 1.00 86.42  ? 357 HIS A CA  1 
ATOM   2691  C C   . HIS A 1 349 ? -11.704 80.496  64.879 1.00 94.44  ? 357 HIS A C   1 
ATOM   2692  O O   . HIS A 1 349 ? -11.423 81.689  64.661 1.00 80.53  ? 357 HIS A O   1 
ATOM   2693  C CB  . HIS A 1 349 ? -10.208 79.409  63.225 1.00 86.07  ? 357 HIS A CB  1 
ATOM   2694  C CG  . HIS A 1 349 ? -11.334 79.018  62.327 1.00 93.92  ? 357 HIS A CG  1 
ATOM   2695  N ND1 . HIS A 1 349 ? -12.125 77.893  62.497 1.00 105.96 ? 357 HIS A ND1 1 
ATOM   2696  C CD2 . HIS A 1 349 ? -11.815 79.640  61.258 1.00 103.71 ? 357 HIS A CD2 1 
ATOM   2697  C CE1 . HIS A 1 349 ? -13.024 77.828  61.520 1.00 104.30 ? 357 HIS A CE1 1 
ATOM   2698  N NE2 . HIS A 1 349 ? -12.866 78.889  60.762 1.00 112.19 ? 357 HIS A NE2 1 
ATOM   2699  N N   . LEU A 1 350 ? -12.941 80.112  65.245 1.00 86.72  ? 358 LEU A N   1 
ATOM   2700  C CA  . LEU A 1 350 ? -14.013 81.103  65.310 1.00 78.74  ? 358 LEU A CA  1 
ATOM   2701  C C   . LEU A 1 350 ? -14.816 80.963  66.598 1.00 74.27  ? 358 LEU A C   1 
ATOM   2702  O O   . LEU A 1 350 ? -14.900 79.863  67.184 1.00 80.45  ? 358 LEU A O   1 
ATOM   2703  C CB  . LEU A 1 350 ? -14.937 81.136  64.087 1.00 63.62  ? 358 LEU A CB  1 
ATOM   2704  C CG  . LEU A 1 350 ? -15.811 79.898  63.852 1.00 75.28  ? 358 LEU A CG  1 
ATOM   2705  C CD1 . LEU A 1 350 ? -17.054 79.721  64.796 1.00 68.09  ? 358 LEU A CD1 1 
ATOM   2706  C CD2 . LEU A 1 350 ? -16.163 79.741  62.377 1.00 75.55  ? 358 LEU A CD2 1 
ATOM   2707  N N   . ILE A 1 351 ? -15.494 82.074  66.941 1.00 63.30  ? 359 ILE A N   1 
ATOM   2708  C CA  . ILE A 1 351 ? -16.492 82.081  68.007 1.00 79.39  ? 359 ILE A CA  1 
ATOM   2709  C C   . ILE A 1 351 ? -17.744 82.770  67.513 1.00 69.43  ? 359 ILE A C   1 
ATOM   2710  O O   . ILE A 1 351 ? -17.683 83.620  66.599 1.00 67.52  ? 359 ILE A O   1 
ATOM   2711  C CB  . ILE A 1 351 ? -15.985 82.814  69.256 1.00 96.63  ? 359 ILE A CB  1 
ATOM   2712  C CG1 . ILE A 1 351 ? -15.366 84.185  68.836 1.00 81.03  ? 359 ILE A CG1 1 
ATOM   2713  C CG2 . ILE A 1 351 ? -15.047 81.903  70.054 1.00 95.57  ? 359 ILE A CG2 1 
ATOM   2714  C CD1 . ILE A 1 351 ? -14.723 84.964  69.960 1.00 83.88  ? 359 ILE A CD1 1 
ATOM   2715  N N   . LEU A 1 352 ? -18.858 82.386  68.152 1.00 62.51  ? 360 LEU A N   1 
ATOM   2716  C CA  . LEU A 1 352 ? -20.086 83.091  67.828 1.00 89.21  ? 360 LEU A CA  1 
ATOM   2717  C C   . LEU A 1 352 ? -20.481 83.874  69.068 1.00 125.50 ? 360 LEU A C   1 
ATOM   2718  O O   . LEU A 1 352 ? -20.799 83.278  70.102 1.00 145.29 ? 360 LEU A O   1 
ATOM   2719  C CB  . LEU A 1 352 ? -21.191 82.141  67.381 1.00 74.84  ? 360 LEU A CB  1 
ATOM   2720  C CG  . LEU A 1 352 ? -22.561 82.746  67.091 1.00 67.06  ? 360 LEU A CG  1 
ATOM   2721  C CD1 . LEU A 1 352 ? -22.420 83.784  66.026 1.00 72.46  ? 360 LEU A CD1 1 
ATOM   2722  C CD2 . LEU A 1 352 ? -23.516 81.671  66.645 1.00 60.26  ? 360 LEU A CD2 1 
ATOM   2723  N N   . VAL A 1 353 ? -20.442 85.206  68.945 1.00 115.97 ? 361 VAL A N   1 
ATOM   2724  C CA  . VAL A 1 353 ? -20.724 86.053  70.091 1.00 95.20  ? 361 VAL A CA  1 
ATOM   2725  C C   . VAL A 1 353 ? -22.193 86.449  70.058 1.00 99.61  ? 361 VAL A C   1 
ATOM   2726  O O   . VAL A 1 353 ? -22.665 87.103  69.125 1.00 127.03 ? 361 VAL A O   1 
ATOM   2727  C CB  . VAL A 1 353 ? -19.885 87.337  70.103 1.00 85.01  ? 361 VAL A CB  1 
ATOM   2728  C CG1 . VAL A 1 353 ? -20.263 88.222  71.280 1.00 77.00  ? 361 VAL A CG1 1 
ATOM   2729  C CG2 . VAL A 1 353 ? -18.387 87.052  70.045 1.00 72.50  ? 361 VAL A CG2 1 
ATOM   2730  N N   . ASP A 1 354 ? -22.895 86.081  71.125 1.00 73.92  ? 362 ASP A N   1 
ATOM   2731  C CA  . ASP A 1 354 ? -24.282 86.471  71.284 1.00 72.15  ? 362 ASP A CA  1 
ATOM   2732  C C   . ASP A 1 354 ? -24.313 87.859  71.904 1.00 74.73  ? 362 ASP A C   1 
ATOM   2733  O O   . ASP A 1 354 ? -24.268 88.001  73.122 1.00 96.42  ? 362 ASP A O   1 
ATOM   2734  C CB  . ASP A 1 354 ? -24.963 85.490  72.214 1.00 73.97  ? 362 ASP A CB  1 
ATOM   2735  C CG  . ASP A 1 354 ? -26.473 85.519  72.151 1.00 86.83  ? 362 ASP A CG  1 
ATOM   2736  O OD1 . ASP A 1 354 ? -27.030 86.601  71.789 1.00 83.17  ? 362 ASP A OD1 1 
ATOM   2737  O OD2 . ASP A 1 354 ? -27.034 84.447  72.422 1.00 99.19  ? 362 ASP A OD2 1 
ATOM   2738  N N   . LEU A 1 355 ? -24.331 88.899  71.076 1.00 59.66  ? 363 LEU A N   1 
ATOM   2739  C CA  . LEU A 1 355 ? -24.357 90.244  71.624 1.00 79.23  ? 363 LEU A CA  1 
ATOM   2740  C C   . LEU A 1 355 ? -25.552 90.497  72.560 1.00 101.22 ? 363 LEU A C   1 
ATOM   2741  O O   . LEU A 1 355 ? -25.659 91.575  73.116 1.00 106.66 ? 363 LEU A O   1 
ATOM   2742  C CB  . LEU A 1 355 ? -24.334 91.238  70.460 1.00 70.39  ? 363 LEU A CB  1 
ATOM   2743  C CG  . LEU A 1 355 ? -22.955 91.493  69.861 1.00 77.37  ? 363 LEU A CG  1 
ATOM   2744  C CD1 . LEU A 1 355 ? -23.120 92.508  68.759 1.00 97.24  ? 363 LEU A CD1 1 
ATOM   2745  C CD2 . LEU A 1 355 ? -21.987 91.942  70.932 1.00 66.79  ? 363 LEU A CD2 1 
ATOM   2746  N N   . ARG A 1 356 ? -26.453 89.534  72.759 1.00 93.93  ? 364 ARG A N   1 
ATOM   2747  C CA  . ARG A 1 356 ? -27.573 89.785  73.656 1.00 96.40  ? 364 ARG A CA  1 
ATOM   2748  C C   . ARG A 1 356 ? -27.105 90.063  75.082 1.00 102.21 ? 364 ARG A C   1 
ATOM   2749  O O   . ARG A 1 356 ? -27.742 90.847  75.771 1.00 103.62 ? 364 ARG A O   1 
ATOM   2750  C CB  . ARG A 1 356 ? -28.683 88.730  73.618 1.00 80.88  ? 364 ARG A CB  1 
ATOM   2751  C CG  . ARG A 1 356 ? -29.436 88.850  72.295 1.00 82.69  ? 364 ARG A CG  1 
ATOM   2752  C CD  . ARG A 1 356 ? -30.517 87.794  72.184 1.00 71.76  ? 364 ARG A CD  1 
ATOM   2753  N NE  . ARG A 1 356 ? -30.068 86.420  72.491 1.00 67.21  ? 364 ARG A NE  1 
ATOM   2754  C CZ  . ARG A 1 356 ? -30.396 85.319  71.806 1.00 65.84  ? 364 ARG A CZ  1 
ATOM   2755  N NH1 . ARG A 1 356 ? -31.094 85.337  70.695 1.00 83.28  ? 364 ARG A NH1 1 
ATOM   2756  N NH2 . ARG A 1 356 ? -29.957 84.163  72.185 1.00 94.34  ? 364 ARG A NH2 1 
ATOM   2757  N N   . SER A 1 357 ? -25.986 89.459  75.499 1.00 112.28 ? 365 SER A N   1 
ATOM   2758  C CA  . SER A 1 357 ? -25.377 89.692  76.801 1.00 99.27  ? 365 SER A CA  1 
ATOM   2759  C C   . SER A 1 357 ? -24.986 91.166  76.987 1.00 102.43 ? 365 SER A C   1 
ATOM   2760  O O   . SER A 1 357 ? -24.719 91.614  78.096 1.00 110.40 ? 365 SER A O   1 
ATOM   2761  C CB  . SER A 1 357 ? -24.173 88.794  76.970 1.00 98.99  ? 365 SER A CB  1 
ATOM   2762  O OG  . SER A 1 357 ? -23.167 89.087  75.997 1.00 68.71  ? 365 SER A OG  1 
ATOM   2763  N N   . LYS A 1 358 ? -24.927 91.940  75.899 1.00 75.98  ? 366 LYS A N   1 
ATOM   2764  C CA  . LYS A 1 358 ? -24.660 93.372  75.998 1.00 78.92  ? 366 LYS A CA  1 
ATOM   2765  C C   . LYS A 1 358 ? -25.858 94.199  75.491 1.00 90.70  ? 366 LYS A C   1 
ATOM   2766  O O   . LYS A 1 358 ? -25.692 95.395  75.184 1.00 64.61  ? 366 LYS A O   1 
ATOM   2767  C CB  . LYS A 1 358 ? -23.387 93.702  75.194 1.00 79.00  ? 366 LYS A CB  1 
ATOM   2768  C CG  . LYS A 1 358 ? -22.053 93.830  75.943 1.00 82.62  ? 366 LYS A CG  1 
ATOM   2769  C CD  . LYS A 1 358 ? -21.571 92.592  76.696 1.00 95.13  ? 366 LYS A CD  1 
ATOM   2770  C CE  . LYS A 1 358 ? -20.518 92.834  77.764 1.00 84.85  ? 366 LYS A CE  1 
ATOM   2771  N NZ  . LYS A 1 358 ? -20.736 92.088  79.030 1.00 58.89  ? 366 LYS A NZ  1 
ATOM   2772  N N   . GLY A 1 359 ? -27.026 93.530  75.323 1.00 86.66  ? 367 GLY A N   1 
ATOM   2773  C CA  . GLY A 1 359 ? -28.334 94.027  74.895 1.00 74.00  ? 367 GLY A CA  1 
ATOM   2774  C C   . GLY A 1 359 ? -28.348 94.634  73.488 1.00 93.65  ? 367 GLY A C   1 
ATOM   2775  O O   . GLY A 1 359 ? -28.792 95.775  73.282 1.00 76.00  ? 367 GLY A O   1 
ATOM   2776  N N   . THR A 1 360 ? -27.877 93.890  72.480 1.00 87.61  ? 368 THR A N   1 
ATOM   2777  C CA  . THR A 1 360 ? -27.833 94.479  71.143 1.00 92.44  ? 368 THR A CA  1 
ATOM   2778  C C   . THR A 1 360 ? -27.784 93.313  70.174 1.00 107.51 ? 368 THR A C   1 
ATOM   2779  O O   . THR A 1 360 ? -27.818 92.180  70.634 1.00 138.15 ? 368 THR A O   1 
ATOM   2780  C CB  . THR A 1 360 ? -26.624 95.412  71.008 1.00 89.66  ? 368 THR A CB  1 
ATOM   2781  O OG1 . THR A 1 360 ? -26.450 95.969  69.711 1.00 55.36  ? 368 THR A OG1 1 
ATOM   2782  C CG2 . THR A 1 360 ? -25.298 94.686  71.132 1.00 115.53 ? 368 THR A CG2 1 
ATOM   2783  N N   . ASP A 1 361 ? -27.672 93.609  68.874 1.00 110.53 ? 369 ASP A N   1 
ATOM   2784  C CA  . ASP A 1 361 ? -27.713 92.602  67.821 1.00 95.41  ? 369 ASP A CA  1 
ATOM   2785  C C   . ASP A 1 361 ? -26.510 92.755  66.882 1.00 111.72 ? 369 ASP A C   1 
ATOM   2786  O O   . ASP A 1 361 ? -25.943 93.853  66.712 1.00 140.02 ? 369 ASP A O   1 
ATOM   2787  C CB  . ASP A 1 361 ? -29.033 92.713  67.076 1.00 93.52  ? 369 ASP A CB  1 
ATOM   2788  C CG  . ASP A 1 361 ? -29.200 94.029  66.310 1.00 107.50 ? 369 ASP A CG  1 
ATOM   2789  O OD1 . ASP A 1 361 ? -28.708 94.123  65.141 1.00 62.94  ? 369 ASP A OD1 1 
ATOM   2790  O OD2 . ASP A 1 361 ? -29.773 94.981  66.904 1.00 133.53 ? 369 ASP A OD2 1 
ATOM   2791  N N   . GLY A 1 362 ? -26.150 91.644  66.231 1.00 107.70 ? 370 GLY A N   1 
ATOM   2792  C CA  . GLY A 1 362 ? -25.053 91.665  65.275 1.00 126.59 ? 370 GLY A CA  1 
ATOM   2793  C C   . GLY A 1 362 ? -25.326 92.578  64.078 1.00 122.36 ? 370 GLY A C   1 
ATOM   2794  O O   . GLY A 1 362 ? -24.381 93.026  63.405 1.00 124.80 ? 370 GLY A O   1 
ATOM   2795  N N   . GLY A 1 363 ? -26.632 92.806  63.818 1.00 89.41  ? 371 GLY A N   1 
ATOM   2796  C CA  . GLY A 1 363 ? -27.045 93.591  62.667 1.00 113.21 ? 371 GLY A CA  1 
ATOM   2797  C C   . GLY A 1 363 ? -26.393 94.969  62.724 1.00 129.63 ? 371 GLY A C   1 
ATOM   2798  O O   . GLY A 1 363 ? -25.777 95.430  61.752 1.00 118.25 ? 371 GLY A O   1 
ATOM   2799  N N   . ARG A 1 364 ? -26.513 95.553  63.920 1.00 132.75 ? 372 ARG A N   1 
ATOM   2800  C CA  . ARG A 1 364 ? -26.062 96.897  64.232 1.00 109.12 ? 372 ARG A CA  1 
ATOM   2801  C C   . ARG A 1 364 ? -24.563 96.889  64.413 1.00 105.23 ? 372 ARG A C   1 
ATOM   2802  O O   . ARG A 1 364 ? -23.881 97.695  63.791 1.00 107.27 ? 372 ARG A O   1 
ATOM   2803  C CB  . ARG A 1 364 ? -26.728 97.415  65.512 1.00 78.33  ? 372 ARG A CB  1 
ATOM   2804  C CG  . ARG A 1 364 ? -28.213 97.684  65.312 1.00 87.45  ? 372 ARG A CG  1 
ATOM   2805  C CD  . ARG A 1 364 ? -28.991 97.928  66.589 1.00 107.61 ? 372 ARG A CD  1 
ATOM   2806  N NE  . ARG A 1 364 ? -30.348 97.810  66.038 1.00 104.47 ? 372 ARG A NE  1 
ATOM   2807  C CZ  . ARG A 1 364 ? -31.159 98.855  65.844 1.00 109.93 ? 372 ARG A CZ  1 
ATOM   2808  N NH1 . ARG A 1 364 ? -31.024 99.971  66.563 1.00 90.95  ? 372 ARG A NH1 1 
ATOM   2809  N NH2 . ARG A 1 364 ? -32.190 98.715  65.031 1.00 116.56 ? 372 ARG A NH2 1 
ATOM   2810  N N   . ALA A 1 365 ? -24.101 95.955  65.252 1.00 108.07 ? 373 ALA A N   1 
ATOM   2811  C CA  . ALA A 1 365 ? -22.715 95.925  65.686 1.00 117.64 ? 373 ALA A CA  1 
ATOM   2812  C C   . ALA A 1 365 ? -21.821 95.829  64.456 1.00 111.85 ? 373 ALA A C   1 
ATOM   2813  O O   . ALA A 1 365 ? -20.905 96.629  64.282 1.00 101.65 ? 373 ALA A O   1 
ATOM   2814  C CB  . ALA A 1 365 ? -22.487 94.766  66.618 1.00 119.21 ? 373 ALA A CB  1 
ATOM   2815  N N   . GLU A 1 366 ? -22.163 94.884  63.580 1.00 104.31 ? 374 GLU A N   1 
ATOM   2816  C CA  . GLU A 1 366 ? -21.397 94.693  62.368 1.00 101.76 ? 374 GLU A CA  1 
ATOM   2817  C C   . GLU A 1 366 ? -21.128 96.044  61.698 1.00 109.93 ? 374 GLU A C   1 
ATOM   2818  O O   . GLU A 1 366 ? -19.981 96.326  61.386 1.00 80.36  ? 374 GLU A O   1 
ATOM   2819  C CB  . GLU A 1 366 ? -22.113 93.666  61.497 1.00 110.10 ? 374 GLU A CB  1 
ATOM   2820  C CG  . GLU A 1 366 ? -21.592 93.613  60.058 1.00 88.61  ? 374 GLU A CG  1 
ATOM   2821  C CD  . GLU A 1 366 ? -22.593 92.884  59.207 1.00 85.54  ? 374 GLU A CD  1 
ATOM   2822  O OE1 . GLU A 1 366 ? -23.706 93.417  59.090 1.00 98.20  ? 374 GLU A OE1 1 
ATOM   2823  O OE2 . GLU A 1 366 ? -22.251 91.807  58.719 1.00 98.71  ? 374 GLU A OE2 1 
ATOM   2824  N N   . LYS A 1 367 ? -22.156 96.891  61.537 1.00 110.81 ? 375 LYS A N   1 
ATOM   2825  C CA  . LYS A 1 367 ? -22.056 98.122  60.760 1.00 100.93 ? 375 LYS A CA  1 
ATOM   2826  C C   . LYS A 1 367 ? -21.154 99.156  61.440 1.00 122.49 ? 375 LYS A C   1 
ATOM   2827  O O   . LYS A 1 367 ? -20.347 99.796  60.761 1.00 135.76 ? 375 LYS A O   1 
ATOM   2828  C CB  . LYS A 1 367 ? -23.430 98.701  60.416 1.00 105.58 ? 375 LYS A CB  1 
ATOM   2829  C CG  . LYS A 1 367 ? -24.264 97.916  59.427 1.00 107.09 ? 375 LYS A CG  1 
ATOM   2830  C CD  . LYS A 1 367 ? -23.645 97.726  58.047 1.00 104.59 ? 375 LYS A CD  1 
ATOM   2831  C CE  . LYS A 1 367 ? -24.491 96.853  57.170 1.00 96.44  ? 375 LYS A CE  1 
ATOM   2832  N NZ  . LYS A 1 367 ? -23.848 95.834  56.308 1.00 93.62  ? 375 LYS A NZ  1 
ATOM   2833  N N   . VAL A 1 368 ? -21.325 99.317  62.763 1.00 121.78 ? 376 VAL A N   1 
ATOM   2834  C CA  . VAL A 1 368 ? -20.514 100.172 63.625 1.00 113.47 ? 376 VAL A CA  1 
ATOM   2835  C C   . VAL A 1 368 ? -19.039 99.819  63.430 1.00 96.58  ? 376 VAL A C   1 
ATOM   2836  O O   . VAL A 1 368 ? -18.220 100.701 63.106 1.00 74.75  ? 376 VAL A O   1 
ATOM   2837  C CB  . VAL A 1 368 ? -20.851 99.914  65.111 1.00 101.48 ? 376 VAL A CB  1 
ATOM   2838  C CG1 . VAL A 1 368 ? -20.053 100.835 66.029 1.00 93.94  ? 376 VAL A CG1 1 
ATOM   2839  C CG2 . VAL A 1 368 ? -22.331 99.993  65.435 1.00 71.53  ? 376 VAL A CG2 1 
ATOM   2840  N N   . LEU A 1 369 ? -18.783 98.521  63.657 1.00 71.79  ? 377 LEU A N   1 
ATOM   2841  C CA  . LEU A 1 369 ? -17.443 97.994  63.773 1.00 75.64  ? 377 LEU A CA  1 
ATOM   2842  C C   . LEU A 1 369 ? -16.814 98.164  62.414 1.00 85.11  ? 377 LEU A C   1 
ATOM   2843  O O   . LEU A 1 369 ? -15.633 98.483  62.344 1.00 84.69  ? 377 LEU A O   1 
ATOM   2844  C CB  . LEU A 1 369 ? -17.447 96.529  64.189 1.00 75.22  ? 377 LEU A CB  1 
ATOM   2845  C CG  . LEU A 1 369 ? -17.851 96.229  65.633 1.00 89.19  ? 377 LEU A CG  1 
ATOM   2846  C CD1 . LEU A 1 369 ? -18.527 94.866  65.817 1.00 83.98  ? 377 LEU A CD1 1 
ATOM   2847  C CD2 . LEU A 1 369 ? -16.543 96.269  66.368 1.00 111.53 ? 377 LEU A CD2 1 
ATOM   2848  N N   . GLU A 1 370 ? -17.616 97.936  61.360 1.00 85.31  ? 378 GLU A N   1 
ATOM   2849  C CA  . GLU A 1 370 ? -17.183 98.118  59.977 1.00 109.30 ? 378 GLU A CA  1 
ATOM   2850  C C   . GLU A 1 370 ? -16.660 99.540  59.789 1.00 106.41 ? 378 GLU A C   1 
ATOM   2851  O O   . GLU A 1 370 ? -15.599 99.734  59.187 1.00 100.30 ? 378 GLU A O   1 
ATOM   2852  C CB  . GLU A 1 370 ? -18.344 97.813  59.026 1.00 117.33 ? 378 GLU A CB  1 
ATOM   2853  C CG  . GLU A 1 370 ? -18.161 98.185  57.552 1.00 116.05 ? 378 GLU A CG  1 
ATOM   2854  C CD  . GLU A 1 370 ? -19.277 97.638  56.634 1.00 125.32 ? 378 GLU A CD  1 
ATOM   2855  O OE1 . GLU A 1 370 ? -20.498 97.754  56.945 1.00 97.52  ? 378 GLU A OE1 1 
ATOM   2856  O OE2 . GLU A 1 370 ? -18.963 97.077  55.550 1.00 108.89 ? 378 GLU A OE2 1 
ATOM   2857  N N   . ALA A 1 371 ? -17.434 100.505 60.315 1.00 83.73  ? 379 ALA A N   1 
ATOM   2858  C CA  . ALA A 1 371 ? -17.138 101.913 60.192 1.00 89.12  ? 379 ALA A CA  1 
ATOM   2859  C C   . ALA A 1 371 ? -15.880 102.258 60.991 1.00 94.42  ? 379 ALA A C   1 
ATOM   2860  O O   . ALA A 1 371 ? -15.282 103.312 60.779 1.00 87.12  ? 379 ALA A O   1 
ATOM   2861  C CB  . ALA A 1 371 ? -18.343 102.715 60.609 1.00 95.33  ? 379 ALA A CB  1 
ATOM   2862  N N   . CYS A 1 372 ? -15.468 101.368 61.905 1.00 89.17  ? 380 CYS A N   1 
ATOM   2863  C CA  . CYS A 1 372 ? -14.257 101.581 62.691 1.00 86.49  ? 380 CYS A CA  1 
ATOM   2864  C C   . CYS A 1 372 ? -13.122 100.708 62.176 1.00 101.39 ? 380 CYS A C   1 
ATOM   2865  O O   . CYS A 1 372 ? -12.123 100.524 62.886 1.00 102.62 ? 380 CYS A O   1 
ATOM   2866  C CB  . CYS A 1 372 ? -14.437 101.246 64.165 1.00 63.77  ? 380 CYS A CB  1 
ATOM   2867  S SG  . CYS A 1 372 ? -15.859 102.132 64.834 1.00 92.45  ? 380 CYS A SG  1 
ATOM   2868  N N   . SER A 1 373 ? -13.287 100.176 60.949 1.00 84.45  ? 381 SER A N   1 
ATOM   2869  C CA  . SER A 1 373 ? -12.248 99.370  60.308 1.00 71.42  ? 381 SER A CA  1 
ATOM   2870  C C   . SER A 1 373 ? -12.035 98.016  60.985 1.00 78.33  ? 381 SER A C   1 
ATOM   2871  O O   . SER A 1 373 ? -10.969 97.421  60.811 1.00 84.40  ? 381 SER A O   1 
ATOM   2872  C CB  . SER A 1 373 ? -10.927 100.082 60.226 1.00 47.32  ? 381 SER A CB  1 
ATOM   2873  O OG  . SER A 1 373 ? -11.139 101.317 59.544 1.00 48.92  ? 381 SER A OG  1 
ATOM   2874  N N   . ILE A 1 374 ? -13.050 97.548  61.723 1.00 68.78  ? 382 ILE A N   1 
ATOM   2875  C CA  . ILE A 1 374 ? -13.044 96.232  62.336 1.00 77.78  ? 382 ILE A CA  1 
ATOM   2876  C C   . ILE A 1 374 ? -14.036 95.384  61.538 1.00 98.19  ? 382 ILE A C   1 
ATOM   2877  O O   . ILE A 1 374 ? -15.251 95.524  61.692 1.00 112.46 ? 382 ILE A O   1 
ATOM   2878  C CB  . ILE A 1 374 ? -13.445 96.326  63.826 1.00 85.61  ? 382 ILE A CB  1 
ATOM   2879  C CG1 . ILE A 1 374 ? -12.538 97.258  64.574 1.00 100.15 ? 382 ILE A CG1 1 
ATOM   2880  C CG2 . ILE A 1 374 ? -13.465 94.943  64.484 1.00 92.99  ? 382 ILE A CG2 1 
ATOM   2881  C CD1 . ILE A 1 374 ? -12.786 97.302  66.073 1.00 132.66 ? 382 ILE A CD1 1 
ATOM   2882  N N   . ALA A 1 375 ? -13.515 94.508  60.682 1.00 94.46  ? 383 ALA A N   1 
ATOM   2883  C CA  . ALA A 1 375 ? -14.399 93.658  59.897 1.00 81.81  ? 383 ALA A CA  1 
ATOM   2884  C C   . ALA A 1 375 ? -14.746 92.402  60.703 1.00 80.05  ? 383 ALA A C   1 
ATOM   2885  O O   . ALA A 1 375 ? -13.860 91.628  61.053 1.00 74.86  ? 383 ALA A O   1 
ATOM   2886  C CB  . ALA A 1 375 ? -13.803 93.345  58.522 1.00 58.27  ? 383 ALA A CB  1 
ATOM   2887  N N   . CYS A 1 376 ? -16.046 92.220  60.991 1.00 76.42  ? 384 CYS A N   1 
ATOM   2888  C CA  . CYS A 1 376 ? -16.611 90.892  61.193 1.00 80.19  ? 384 CYS A CA  1 
ATOM   2889  C C   . CYS A 1 376 ? -17.902 90.705  60.377 1.00 78.01  ? 384 CYS A C   1 
ATOM   2890  O O   . CYS A 1 376 ? -18.225 91.519  59.519 1.00 75.96  ? 384 CYS A O   1 
ATOM   2891  C CB  . CYS A 1 376 ? -16.749 90.695  62.682 1.00 70.93  ? 384 CYS A CB  1 
ATOM   2892  S SG  . CYS A 1 376 ? -18.176 91.597  63.301 1.00 109.42 ? 384 CYS A SG  1 
ATOM   2893  N N   . ASN A 1 377 ? -18.672 89.652  60.654 1.00 83.16  ? 385 ASN A N   1 
ATOM   2894  C CA  . ASN A 1 377 ? -19.902 89.416  59.906 1.00 82.01  ? 385 ASN A CA  1 
ATOM   2895  C C   . ASN A 1 377 ? -20.985 89.103  60.939 1.00 84.02  ? 385 ASN A C   1 
ATOM   2896  O O   . ASN A 1 377 ? -20.671 88.452  61.961 1.00 84.69  ? 385 ASN A O   1 
ATOM   2897  C CB  . ASN A 1 377 ? -19.699 88.368  58.805 1.00 77.15  ? 385 ASN A CB  1 
ATOM   2898  C CG  . ASN A 1 377 ? -19.421 86.991  59.372 1.00 111.09 ? 385 ASN A CG  1 
ATOM   2899  O OD1 . ASN A 1 377 ? -18.271 86.632  59.692 1.00 113.18 ? 385 ASN A OD1 1 
ATOM   2900  N ND2 . ASN A 1 377 ? -20.485 86.208  59.533 1.00 101.08 ? 385 ASN A ND2 1 
ATOM   2901  N N   . LYS A 1 378 ? -22.228 89.580  60.685 1.00 63.74  ? 386 LYS A N   1 
ATOM   2902  C CA  . LYS A 1 378 ? -23.305 89.364  61.658 1.00 76.51  ? 386 LYS A CA  1 
ATOM   2903  C C   . LYS A 1 378 ? -23.632 87.862  61.669 1.00 74.07  ? 386 LYS A C   1 
ATOM   2904  O O   . LYS A 1 378 ? -22.868 87.082  61.118 1.00 74.86  ? 386 LYS A O   1 
ATOM   2905  C CB  . LYS A 1 378 ? -24.480 90.333  61.454 1.00 61.27  ? 386 LYS A CB  1 
ATOM   2906  C CG  . LYS A 1 378 ? -24.971 90.296  60.040 1.00 67.29  ? 386 LYS A CG  1 
ATOM   2907  C CD  . LYS A 1 378 ? -26.377 90.846  59.781 1.00 61.54  ? 386 LYS A CD  1 
ATOM   2908  C CE  . LYS A 1 378 ? -26.657 91.151  58.308 1.00 73.99  ? 386 LYS A CE  1 
ATOM   2909  N NZ  . LYS A 1 378 ? -25.661 91.938  57.528 1.00 67.44  ? 386 LYS A NZ  1 
ATOM   2910  N N   . ASN A 1 379 ? -24.715 87.408  62.326 1.00 58.14  ? 387 ASN A N   1 
ATOM   2911  C CA  . ASN A 1 379 ? -24.988 85.967  62.286 1.00 68.53  ? 387 ASN A CA  1 
ATOM   2912  C C   . ASN A 1 379 ? -25.988 85.573  63.381 1.00 84.13  ? 387 ASN A C   1 
ATOM   2913  O O   . ASN A 1 379 ? -25.799 85.952  64.541 1.00 88.30  ? 387 ASN A O   1 
ATOM   2914  C CB  . ASN A 1 379 ? -23.694 85.221  62.616 1.00 70.67  ? 387 ASN A CB  1 
ATOM   2915  C CG  . ASN A 1 379 ? -23.606 83.829  62.052 1.00 88.62  ? 387 ASN A CG  1 
ATOM   2916  O OD1 . ASN A 1 379 ? -24.568 83.062  62.130 1.00 131.79 ? 387 ASN A OD1 1 
ATOM   2917  N ND2 . ASN A 1 379 ? -22.474 83.511  61.425 1.00 68.65  ? 387 ASN A ND2 1 
ATOM   2918  N N   . THR A 1 380 ? -27.008 84.764  63.056 1.00 84.85  ? 388 THR A N   1 
ATOM   2919  C CA  . THR A 1 380 ? -27.925 84.332  64.104 1.00 99.63  ? 388 THR A CA  1 
ATOM   2920  C C   . THR A 1 380 ? -27.204 83.449  65.128 1.00 100.72 ? 388 THR A C   1 
ATOM   2921  O O   . THR A 1 380 ? -26.230 82.778  64.807 1.00 90.88  ? 388 THR A O   1 
ATOM   2922  C CB  . THR A 1 380 ? -29.190 83.695  63.537 1.00 91.30  ? 388 THR A CB  1 
ATOM   2923  O OG1 . THR A 1 380 ? -28.699 82.704  62.632 1.00 85.29  ? 388 THR A OG1 1 
ATOM   2924  C CG2 . THR A 1 380 ? -30.069 84.752  62.884 1.00 93.83  ? 388 THR A CG2 1 
ATOM   2925  N N   . CYS A 1 381 ? -27.668 83.507  66.376 1.00 86.49  ? 389 CYS A N   1 
ATOM   2926  C CA  . CYS A 1 381 ? -27.285 82.536  67.383 1.00 114.63 ? 389 CYS A CA  1 
ATOM   2927  C C   . CYS A 1 381 ? -28.386 81.500  67.456 1.00 116.20 ? 389 CYS A C   1 
ATOM   2928  O O   . CYS A 1 381 ? -29.535 81.856  67.234 1.00 134.33 ? 389 CYS A O   1 
ATOM   2929  C CB  . CYS A 1 381 ? -27.064 83.172  68.754 1.00 116.27 ? 389 CYS A CB  1 
ATOM   2930  S SG  . CYS A 1 381 ? -26.057 84.673  68.609 1.00 59.12  ? 389 CYS A SG  1 
ATOM   2931  N N   . PRO A 1 382 ? -28.087 80.209  67.717 1.00 125.32 ? 390 PRO A N   1 
ATOM   2932  C CA  . PRO A 1 382 ? -29.148 79.204  67.837 1.00 123.45 ? 390 PRO A CA  1 
ATOM   2933  C C   . PRO A 1 382 ? -30.296 79.716  68.712 1.00 119.64 ? 390 PRO A C   1 
ATOM   2934  O O   . PRO A 1 382 ? -30.033 80.226  69.827 1.00 90.52  ? 390 PRO A O   1 
ATOM   2935  C CB  . PRO A 1 382 ? -28.389 78.017  68.460 1.00 118.22 ? 390 PRO A CB  1 
ATOM   2936  C CG  . PRO A 1 382 ? -26.961 78.179  67.942 1.00 139.52 ? 390 PRO A CG  1 
ATOM   2937  C CD  . PRO A 1 382 ? -26.727 79.674  67.892 1.00 129.50 ? 390 PRO A CD  1 
ATOM   2938  N N   . GLY A 1 383 ? -31.534 79.626  68.153 1.00 95.99  ? 391 GLY A N   1 
ATOM   2939  C CA  . GLY A 1 383 ? -32.760 80.004  68.846 1.00 117.57 ? 391 GLY A CA  1 
ATOM   2940  C C   . GLY A 1 383 ? -32.996 81.523  68.900 1.00 123.11 ? 391 GLY A C   1 
ATOM   2941  O O   . GLY A 1 383 ? -33.697 82.035  69.771 1.00 101.48 ? 391 GLY A O   1 
ATOM   2942  N N   . ASP A 1 384 ? -32.363 82.270  67.993 1.00 120.42 ? 392 ASP A N   1 
ATOM   2943  C CA  . ASP A 1 384 ? -32.705 83.675  67.813 1.00 105.81 ? 392 ASP A CA  1 
ATOM   2944  C C   . ASP A 1 384 ? -34.181 83.736  67.452 1.00 118.12 ? 392 ASP A C   1 
ATOM   2945  O O   . ASP A 1 384 ? -34.655 82.858  66.720 1.00 119.36 ? 392 ASP A O   1 
ATOM   2946  C CB  . ASP A 1 384 ? -31.888 84.331  66.713 1.00 95.07  ? 392 ASP A CB  1 
ATOM   2947  C CG  . ASP A 1 384 ? -30.592 84.969  67.174 1.00 83.97  ? 392 ASP A CG  1 
ATOM   2948  O OD1 . ASP A 1 384 ? -30.308 84.900  68.395 1.00 85.30  ? 392 ASP A OD1 1 
ATOM   2949  O OD2 . ASP A 1 384 ? -29.834 85.431  66.309 1.00 73.09  ? 392 ASP A OD2 1 
ATOM   2950  N N   . ARG A 1 385 ? -34.901 84.728  67.985 1.00 109.09 ? 393 ARG A N   1 
ATOM   2951  C CA  . ARG A 1 385 ? -36.298 84.826  67.592 1.00 96.49  ? 393 ARG A CA  1 
ATOM   2952  C C   . ARG A 1 385 ? -36.436 84.730  66.060 1.00 78.68  ? 393 ARG A C   1 
ATOM   2953  O O   . ARG A 1 385 ? -36.945 83.732  65.566 1.00 76.85  ? 393 ARG A O   1 
ATOM   2954  C CB  . ARG A 1 385 ? -37.053 85.875  68.401 1.00 100.29 ? 393 ARG A CB  1 
ATOM   2955  C CG  . ARG A 1 385 ? -37.926 85.104  69.383 1.00 93.92  ? 393 ARG A CG  1 
ATOM   2956  C CD  . ARG A 1 385 ? -39.027 84.270  68.695 1.00 94.71  ? 393 ARG A CD  1 
ATOM   2957  N NE  . ARG A 1 385 ? -39.446 83.223  69.639 1.00 122.53 ? 393 ARG A NE  1 
ATOM   2958  C CZ  . ARG A 1 385 ? -39.980 83.393  70.859 1.00 118.59 ? 393 ARG A CZ  1 
ATOM   2959  N NH1 . ARG A 1 385 ? -40.591 84.528  71.182 1.00 119.88 ? 393 ARG A NH1 1 
ATOM   2960  N NH2 . ARG A 1 385 ? -39.928 82.401  71.746 1.00 86.09  ? 393 ARG A NH2 1 
ATOM   2961  N N   . SER A 1 386 ? -35.881 85.682  65.310 1.00 57.37  ? 394 SER A N   1 
ATOM   2962  C CA  . SER A 1 386 ? -36.140 85.820  63.882 1.00 73.82  ? 394 SER A CA  1 
ATOM   2963  C C   . SER A 1 386 ? -34.827 86.025  63.134 1.00 81.76  ? 394 SER A C   1 
ATOM   2964  O O   . SER A 1 386 ? -33.891 86.585  63.688 1.00 109.55 ? 394 SER A O   1 
ATOM   2965  C CB  . SER A 1 386 ? -37.052 87.020  63.690 1.00 100.67 ? 394 SER A CB  1 
ATOM   2966  O OG  . SER A 1 386 ? -36.914 87.638  62.409 1.00 129.94 ? 394 SER A OG  1 
ATOM   2967  N N   . ALA A 1 387 ? -34.787 85.609  61.867 1.00 97.41  ? 395 ALA A N   1 
ATOM   2968  C CA  . ALA A 1 387 ? -33.607 85.772  61.028 1.00 118.78 ? 395 ALA A CA  1 
ATOM   2969  C C   . ALA A 1 387 ? -33.370 87.257  60.717 1.00 119.14 ? 395 ALA A C   1 
ATOM   2970  O O   . ALA A 1 387 ? -32.259 87.619  60.302 1.00 108.20 ? 395 ALA A O   1 
ATOM   2971  C CB  . ALA A 1 387 ? -33.708 84.885  59.760 1.00 87.82  ? 395 ALA A CB  1 
ATOM   2972  N N   . LEU A 1 388 ? -34.420 88.082  60.918 1.00 105.48 ? 396 LEU A N   1 
ATOM   2973  C CA  . LEU A 1 388 ? -34.413 89.498  60.587 1.00 107.09 ? 396 LEU A CA  1 
ATOM   2974  C C   . LEU A 1 388 ? -33.613 90.273  61.631 1.00 117.89 ? 396 LEU A C   1 
ATOM   2975  O O   . LEU A 1 388 ? -33.093 91.333  61.276 1.00 137.81 ? 396 LEU A O   1 
ATOM   2976  C CB  . LEU A 1 388 ? -35.815 90.083  60.371 1.00 93.44  ? 396 LEU A CB  1 
ATOM   2977  C CG  . LEU A 1 388 ? -36.557 89.656  59.086 1.00 103.88 ? 396 LEU A CG  1 
ATOM   2978  C CD1 . LEU A 1 388 ? -38.003 90.180  59.104 1.00 92.36  ? 396 LEU A CD1 1 
ATOM   2979  C CD2 . LEU A 1 388 ? -35.890 89.861  57.682 1.00 57.49  ? 396 LEU A CD2 1 
ATOM   2980  N N   . ARG A 1 389 ? -33.543 89.769  62.890 1.00 87.73  ? 397 ARG A N   1 
ATOM   2981  C CA  . ARG A 1 389 ? -32.750 90.400  63.941 1.00 105.33 ? 397 ARG A CA  1 
ATOM   2982  C C   . ARG A 1 389 ? -31.716 89.433  64.526 1.00 111.65 ? 397 ARG A C   1 
ATOM   2983  O O   . ARG A 1 389 ? -31.893 88.943  65.657 1.00 92.52  ? 397 ARG A O   1 
ATOM   2984  C CB  . ARG A 1 389 ? -33.573 91.145  65.000 1.00 110.66 ? 397 ARG A CB  1 
ATOM   2985  C CG  . ARG A 1 389 ? -32.774 91.776  66.133 1.00 116.98 ? 397 ARG A CG  1 
ATOM   2986  C CD  . ARG A 1 389 ? -33.625 92.882  66.836 1.00 98.37  ? 397 ARG A CD  1 
ATOM   2987  N NE  . ARG A 1 389 ? -34.151 93.851  65.859 1.00 117.72 ? 397 ARG A NE  1 
ATOM   2988  C CZ  . ARG A 1 389 ? -33.538 94.952  65.400 1.00 111.89 ? 397 ARG A CZ  1 
ATOM   2989  N NH1 . ARG A 1 389 ? -32.679 95.558  66.219 1.00 78.16  ? 397 ARG A NH1 1 
ATOM   2990  N NH2 . ARG A 1 389 ? -33.850 95.469  64.195 1.00 83.72  ? 397 ARG A NH2 1 
ATOM   2991  N N   . PRO A 1 390 ? -30.588 89.208  63.797 1.00 84.05  ? 398 PRO A N   1 
ATOM   2992  C CA  . PRO A 1 390 ? -29.514 88.320  64.260 1.00 89.31  ? 398 PRO A CA  1 
ATOM   2993  C C   . PRO A 1 390 ? -28.833 88.874  65.515 1.00 120.17 ? 398 PRO A C   1 
ATOM   2994  O O   . PRO A 1 390 ? -28.427 90.041  65.575 1.00 158.85 ? 398 PRO A O   1 
ATOM   2995  C CB  . PRO A 1 390 ? -28.524 88.247  63.084 1.00 85.97  ? 398 PRO A CB  1 
ATOM   2996  C CG  . PRO A 1 390 ? -28.754 89.578  62.369 1.00 104.37 ? 398 PRO A CG  1 
ATOM   2997  C CD  . PRO A 1 390 ? -30.251 89.888  62.536 1.00 85.74  ? 398 PRO A CD  1 
ATOM   2998  N N   . SER A 1 391 ? -28.700 88.008  66.527 1.00 108.33 ? 399 SER A N   1 
ATOM   2999  C CA  . SER A 1 391 ? -28.141 88.434  67.798 1.00 88.27  ? 399 SER A CA  1 
ATOM   3000  C C   . SER A 1 391 ? -26.615 88.374  67.822 1.00 71.60  ? 399 SER A C   1 
ATOM   3001  O O   . SER A 1 391 ? -26.045 88.634  68.896 1.00 71.19  ? 399 SER A O   1 
ATOM   3002  C CB  . SER A 1 391 ? -28.686 87.588  68.917 1.00 72.38  ? 399 SER A CB  1 
ATOM   3003  O OG  . SER A 1 391 ? -30.090 87.711  68.937 1.00 99.06  ? 399 SER A OG  1 
ATOM   3004  N N   . GLY A 1 392 ? -25.996 87.879  66.733 1.00 54.12  ? 400 GLY A N   1 
ATOM   3005  C CA  . GLY A 1 392 ? -24.652 87.297  66.820 1.00 76.73  ? 400 GLY A CA  1 
ATOM   3006  C C   . GLY A 1 392 ? -23.624 87.977  65.912 1.00 90.89  ? 400 GLY A C   1 
ATOM   3007  O O   . GLY A 1 392 ? -23.974 88.585  64.900 1.00 104.92 ? 400 GLY A O   1 
ATOM   3008  N N   . LEU A 1 393 ? -22.351 87.898  66.324 1.00 75.86  ? 401 LEU A N   1 
ATOM   3009  C CA  . LEU A 1 393 ? -21.230 88.256  65.478 1.00 87.66  ? 401 LEU A CA  1 
ATOM   3010  C C   . LEU A 1 393 ? -20.362 87.015  65.358 1.00 103.14 ? 401 LEU A C   1 
ATOM   3011  O O   . LEU A 1 393 ? -20.017 86.394  66.383 1.00 103.93 ? 401 LEU A O   1 
ATOM   3012  C CB  . LEU A 1 393 ? -20.438 89.359  66.167 1.00 86.69  ? 401 LEU A CB  1 
ATOM   3013  C CG  . LEU A 1 393 ? -20.972 90.779  66.002 1.00 99.78  ? 401 LEU A CG  1 
ATOM   3014  C CD1 . LEU A 1 393 ? -19.935 91.675  66.648 1.00 80.79  ? 401 LEU A CD1 1 
ATOM   3015  C CD2 . LEU A 1 393 ? -21.113 91.109  64.510 1.00 122.89 ? 401 LEU A CD2 1 
ATOM   3016  N N   . ARG A 1 394 ? -20.045 86.653  64.102 1.00 74.49  ? 402 ARG A N   1 
ATOM   3017  C CA  . ARG A 1 394 ? -19.081 85.582  63.926 1.00 64.98  ? 402 ARG A CA  1 
ATOM   3018  C C   . ARG A 1 394 ? -17.684 86.199  63.830 1.00 82.92  ? 402 ARG A C   1 
ATOM   3019  O O   . ARG A 1 394 ? -17.441 87.038  62.971 1.00 104.86 ? 402 ARG A O   1 
ATOM   3020  C CB  . ARG A 1 394 ? -19.467 84.762  62.705 1.00 71.22  ? 402 ARG A CB  1 
ATOM   3021  C CG  . ARG A 1 394 ? -18.553 83.550  62.518 1.00 97.87  ? 402 ARG A CG  1 
ATOM   3022  C CD  . ARG A 1 394 ? -18.705 82.831  61.146 1.00 74.78  ? 402 ARG A CD  1 
ATOM   3023  N NE  . ARG A 1 394 ? -18.264 83.690  60.048 1.00 82.77  ? 402 ARG A NE  1 
ATOM   3024  C CZ  . ARG A 1 394 ? -18.280 83.321  58.789 1.00 107.41 ? 402 ARG A CZ  1 
ATOM   3025  N NH1 . ARG A 1 394 ? -18.797 82.159  58.446 1.00 128.41 ? 402 ARG A NH1 1 
ATOM   3026  N NH2 . ARG A 1 394 ? -17.810 84.141  57.866 1.00 141.02 ? 402 ARG A NH2 1 
ATOM   3027  N N   . LEU A 1 395 ? -16.767 85.743  64.696 1.00 75.90  ? 403 LEU A N   1 
ATOM   3028  C CA  . LEU A 1 395 ? -15.401 86.253  64.752 1.00 75.81  ? 403 LEU A CA  1 
ATOM   3029  C C   . LEU A 1 395 ? -14.422 85.098  64.554 1.00 87.68  ? 403 LEU A C   1 
ATOM   3030  O O   . LEU A 1 395 ? -14.628 84.002  65.095 1.00 95.94  ? 403 LEU A O   1 
ATOM   3031  C CB  . LEU A 1 395 ? -15.138 86.870  66.122 1.00 84.72  ? 403 LEU A CB  1 
ATOM   3032  C CG  . LEU A 1 395 ? -16.007 88.041  66.548 1.00 89.71  ? 403 LEU A CG  1 
ATOM   3033  C CD1 . LEU A 1 395 ? -15.520 88.492  67.952 1.00 84.68  ? 403 LEU A CD1 1 
ATOM   3034  C CD2 . LEU A 1 395 ? -15.776 89.124  65.532 1.00 62.30  ? 403 LEU A CD2 1 
ATOM   3035  N N   . GLY A 1 396 ? -13.369 85.341  63.771 1.00 62.78  ? 404 GLY A N   1 
ATOM   3036  C CA  . GLY A 1 396 ? -12.365 84.326  63.545 1.00 49.56  ? 404 GLY A CA  1 
ATOM   3037  C C   . GLY A 1 396 ? -10.971 84.950  63.562 1.00 81.72  ? 404 GLY A C   1 
ATOM   3038  O O   . GLY A 1 396 ? -10.781 86.163  63.287 1.00 93.97  ? 404 GLY A O   1 
ATOM   3039  N N   . THR A 1 397 ? -9.979  84.064  63.771 1.00 78.73  ? 405 THR A N   1 
ATOM   3040  C CA  . THR A 1 397 ? -8.600  84.507  63.911 1.00 82.58  ? 405 THR A CA  1 
ATOM   3041  C C   . THR A 1 397 ? -7.703  84.310  62.696 1.00 103.06 ? 405 THR A C   1 
ATOM   3042  O O   . THR A 1 397 ? -6.638  84.925  62.693 1.00 93.26  ? 405 THR A O   1 
ATOM   3043  C CB  . THR A 1 397 ? -8.018  83.864  65.157 1.00 74.94  ? 405 THR A CB  1 
ATOM   3044  O OG1 . THR A 1 397 ? -8.008  82.461  64.912 1.00 82.60  ? 405 THR A OG1 1 
ATOM   3045  C CG2 . THR A 1 397 ? -8.875  84.219  66.367 1.00 70.68  ? 405 THR A CG2 1 
ATOM   3046  N N   . PRO A 1 398 ? -8.047  83.471  61.679 1.00 115.13 ? 406 PRO A N   1 
ATOM   3047  C CA  . PRO A 1 398 ? -7.101  83.118  60.617 1.00 106.42 ? 406 PRO A CA  1 
ATOM   3048  C C   . PRO A 1 398 ? -6.452  84.336  59.976 1.00 98.07  ? 406 PRO A C   1 
ATOM   3049  O O   . PRO A 1 398 ? -5.216  84.427  59.911 1.00 61.14  ? 406 PRO A O   1 
ATOM   3050  C CB  . PRO A 1 398 ? -7.978  82.397  59.636 1.00 111.01 ? 406 PRO A CB  1 
ATOM   3051  C CG  . PRO A 1 398 ? -8.915  81.670  60.545 1.00 120.44 ? 406 PRO A CG  1 
ATOM   3052  C CD  . PRO A 1 398 ? -9.321  82.752  61.518 1.00 108.43 ? 406 PRO A CD  1 
ATOM   3053  N N   . ALA A 1 399 ? -7.299  85.296  59.576 1.00 87.25  ? 407 ALA A N   1 
ATOM   3054  C CA  . ALA A 1 399 ? -6.766  86.391  58.787 1.00 103.83 ? 407 ALA A CA  1 
ATOM   3055  C C   . ALA A 1 399 ? -5.660  87.138  59.542 1.00 104.86 ? 407 ALA A C   1 
ATOM   3056  O O   . ALA A 1 399 ? -4.532  87.268  59.043 1.00 78.57  ? 407 ALA A O   1 
ATOM   3057  C CB  . ALA A 1 399 ? -7.907  87.281  58.381 1.00 101.67 ? 407 ALA A CB  1 
ATOM   3058  N N   . LEU A 1 400 ? -6.002  87.619  60.753 1.00 105.16 ? 408 LEU A N   1 
ATOM   3059  C CA  . LEU A 1 400 ? -5.083  88.415  61.551 1.00 85.15  ? 408 LEU A CA  1 
ATOM   3060  C C   . LEU A 1 400 ? -3.877  87.575  61.943 1.00 82.29  ? 408 LEU A C   1 
ATOM   3061  O O   . LEU A 1 400 ? -2.780  88.120  62.029 1.00 81.08  ? 408 LEU A O   1 
ATOM   3062  C CB  . LEU A 1 400 ? -5.785  88.959  62.788 1.00 77.71  ? 408 LEU A CB  1 
ATOM   3063  C CG  . LEU A 1 400 ? -6.543  90.266  62.584 1.00 83.70  ? 408 LEU A CG  1 
ATOM   3064  C CD1 . LEU A 1 400 ? -7.223  90.693  63.868 1.00 104.19 ? 408 LEU A CD1 1 
ATOM   3065  C CD2 . LEU A 1 400 ? -5.622  91.357  62.052 1.00 78.93  ? 408 LEU A CD2 1 
ATOM   3066  N N   . THR A 1 401 ? -4.100  86.274  62.223 1.00 65.79  ? 409 THR A N   1 
ATOM   3067  C CA  . THR A 1 401 ? -3.012  85.425  62.687 1.00 57.99  ? 409 THR A CA  1 
ATOM   3068  C C   . THR A 1 401 ? -1.975  85.336  61.579 1.00 60.47  ? 409 THR A C   1 
ATOM   3069  O O   . THR A 1 401 ? -0.779  85.320  61.813 1.00 55.46  ? 409 THR A O   1 
ATOM   3070  C CB  . THR A 1 401 ? -3.493  84.041  63.146 1.00 61.83  ? 409 THR A CB  1 
ATOM   3071  O OG1 . THR A 1 401 ? -4.500  84.207  64.149 1.00 76.17  ? 409 THR A OG1 1 
ATOM   3072  C CG2 . THR A 1 401 ? -2.389  83.206  63.784 1.00 51.46  ? 409 THR A CG2 1 
ATOM   3073  N N   . SER A 1 402 ? -2.447  85.260  60.341 1.00 79.65  ? 410 SER A N   1 
ATOM   3074  C CA  . SER A 1 402 ? -1.540  85.169  59.215 1.00 85.51  ? 410 SER A CA  1 
ATOM   3075  C C   . SER A 1 402 ? -0.738  86.471  59.128 1.00 88.45  ? 410 SER A C   1 
ATOM   3076  O O   . SER A 1 402 ? 0.231   86.579  58.381 1.00 93.87  ? 410 SER A O   1 
ATOM   3077  C CB  . SER A 1 402 ? -2.336  84.957  57.951 1.00 109.18 ? 410 SER A CB  1 
ATOM   3078  O OG  . SER A 1 402 ? -2.963  83.680  57.902 1.00 95.12  ? 410 SER A OG  1 
ATOM   3079  N N   . ARG A 1 403 ? -1.189  87.502  59.848 1.00 79.02  ? 411 ARG A N   1 
ATOM   3080  C CA  . ARG A 1 403 ? -0.487  88.780  59.834 1.00 89.60  ? 411 ARG A CA  1 
ATOM   3081  C C   . ARG A 1 403 ? 0.593   88.768  60.934 1.00 101.91 ? 411 ARG A C   1 
ATOM   3082  O O   . ARG A 1 403 ? 1.591   89.518  60.903 1.00 81.95  ? 411 ARG A O   1 
ATOM   3083  C CB  . ARG A 1 403 ? -1.463  89.963  59.964 1.00 101.29 ? 411 ARG A CB  1 
ATOM   3084  C CG  . ARG A 1 403 ? -2.399  90.081  58.772 1.00 96.30  ? 411 ARG A CG  1 
ATOM   3085  C CD  . ARG A 1 403 ? -3.191  91.364  58.744 1.00 98.78  ? 411 ARG A CD  1 
ATOM   3086  N NE  . ARG A 1 403 ? -2.300  92.504  58.530 1.00 96.94  ? 411 ARG A NE  1 
ATOM   3087  C CZ  . ARG A 1 403 ? -2.736  93.756  58.348 1.00 96.10  ? 411 ARG A CZ  1 
ATOM   3088  N NH1 . ARG A 1 403 ? -4.013  94.065  58.503 1.00 87.93  ? 411 ARG A NH1 1 
ATOM   3089  N NH2 . ARG A 1 403 ? -1.866  94.714  58.082 1.00 88.02  ? 411 ARG A NH2 1 
ATOM   3090  N N   . GLY A 1 404 ? 0.428   87.881  61.915 1.00 79.92  ? 412 GLY A N   1 
ATOM   3091  C CA  . GLY A 1 404 ? 1.470   87.863  62.926 1.00 80.18  ? 412 GLY A CA  1 
ATOM   3092  C C   . GLY A 1 404 ? 0.936   87.985  64.350 1.00 74.27  ? 412 GLY A C   1 
ATOM   3093  O O   . GLY A 1 404 ? 1.639   87.658  65.305 1.00 76.02  ? 412 GLY A O   1 
ATOM   3094  N N   . LEU A 1 405 ? -0.325  88.387  64.488 1.00 76.58  ? 413 LEU A N   1 
ATOM   3095  C CA  . LEU A 1 405 ? -0.925  88.603  65.800 1.00 95.43  ? 413 LEU A CA  1 
ATOM   3096  C C   . LEU A 1 405 ? -0.797  87.353  66.682 1.00 111.49 ? 413 LEU A C   1 
ATOM   3097  O O   . LEU A 1 405 ? -1.030  86.214  66.217 1.00 115.03 ? 413 LEU A O   1 
ATOM   3098  C CB  . LEU A 1 405 ? -2.367  89.098  65.692 1.00 88.44  ? 413 LEU A CB  1 
ATOM   3099  C CG  . LEU A 1 405 ? -2.584  90.574  65.332 1.00 83.59  ? 413 LEU A CG  1 
ATOM   3100  C CD1 . LEU A 1 405 ? -2.370  90.900  63.865 1.00 100.50 ? 413 LEU A CD1 1 
ATOM   3101  C CD2 . LEU A 1 405 ? -3.992  90.955  65.672 1.00 88.38  ? 413 LEU A CD2 1 
ATOM   3102  N N   . LEU A 1 406 ? -0.471  87.596  67.974 1.00 80.02  ? 414 LEU A N   1 
ATOM   3103  C CA  . LEU A 1 406 ? -0.469  86.540  68.977 1.00 88.00  ? 414 LEU A CA  1 
ATOM   3104  C C   . LEU A 1 406 ? -1.515  86.844  70.051 1.00 104.69 ? 414 LEU A C   1 
ATOM   3105  O O   . LEU A 1 406 ? -2.305  87.796  69.885 1.00 80.81  ? 414 LEU A O   1 
ATOM   3106  C CB  . LEU A 1 406 ? 0.916   86.457  69.612 1.00 86.32  ? 414 LEU A CB  1 
ATOM   3107  C CG  . LEU A 1 406 ? 2.118   86.049  68.763 1.00 79.52  ? 414 LEU A CG  1 
ATOM   3108  C CD1 . LEU A 1 406 ? 2.923   85.329  69.882 1.00 78.54  ? 414 LEU A CD1 1 
ATOM   3109  C CD2 . LEU A 1 406 ? 2.045   85.020  67.671 1.00 104.03 ? 414 LEU A CD2 1 
ATOM   3110  N N   . GLU A 1 407 ? -1.472  86.078  71.169 1.00 85.70  ? 415 GLU A N   1 
ATOM   3111  C CA  . GLU A 1 407 ? -2.560  86.151  72.146 1.00 91.66  ? 415 GLU A CA  1 
ATOM   3112  C C   . GLU A 1 407 ? -2.744  87.570  72.689 1.00 105.48 ? 415 GLU A C   1 
ATOM   3113  O O   . GLU A 1 407 ? -3.872  88.058  72.725 1.00 105.70 ? 415 GLU A O   1 
ATOM   3114  C CB  . GLU A 1 407 ? -2.684  85.169  73.317 1.00 75.12  ? 415 GLU A CB  1 
ATOM   3115  C CG  . GLU A 1 407 ? -2.636  83.686  72.963 1.00 94.62  ? 415 GLU A CG  1 
ATOM   3116  C CD  . GLU A 1 407 ? -1.249  83.182  72.583 1.00 115.69 ? 415 GLU A CD  1 
ATOM   3117  O OE1 . GLU A 1 407 ? -0.552  83.852  71.775 1.00 101.28 ? 415 GLU A OE1 1 
ATOM   3118  O OE2 . GLU A 1 407 ? -0.868  82.094  73.081 1.00 94.19  ? 415 GLU A OE2 1 
ATOM   3119  N N   . LYS A 1 408 ? -1.646  88.226  73.106 1.00 131.06 ? 416 LYS A N   1 
ATOM   3120  C CA  . LYS A 1 408 ? -1.775  89.553  73.705 1.00 105.39 ? 416 LYS A CA  1 
ATOM   3121  C C   . LYS A 1 408 ? -2.445  90.473  72.690 1.00 96.22  ? 416 LYS A C   1 
ATOM   3122  O O   . LYS A 1 408 ? -3.352  91.205  73.069 1.00 135.20 ? 416 LYS A O   1 
ATOM   3123  C CB  . LYS A 1 408 ? -0.576  90.099  74.513 1.00 82.96  ? 416 LYS A CB  1 
ATOM   3124  C CG  . LYS A 1 408 ? 0.531   90.964  73.892 1.00 73.86  ? 416 LYS A CG  1 
ATOM   3125  C CD  . LYS A 1 408 ? 0.424   92.498  73.734 1.00 71.82  ? 416 LYS A CD  1 
ATOM   3126  C CE  . LYS A 1 408 ? 1.686   93.111  73.162 1.00 78.35  ? 416 LYS A CE  1 
ATOM   3127  N NZ  . LYS A 1 408 ? 2.285   92.704  71.862 1.00 70.24  ? 416 LYS A NZ  1 
ATOM   3128  N N   . ASP A 1 409 ? -2.018  90.394  71.416 1.00 71.18  ? 417 ASP A N   1 
ATOM   3129  C CA  . ASP A 1 409 ? -2.559  91.219  70.341 1.00 81.84  ? 417 ASP A CA  1 
ATOM   3130  C C   . ASP A 1 409 ? -4.070  91.025  70.206 1.00 103.92 ? 417 ASP A C   1 
ATOM   3131  O O   . ASP A 1 409 ? -4.819  92.002  70.107 1.00 103.94 ? 417 ASP A O   1 
ATOM   3132  C CB  . ASP A 1 409 ? -1.845  90.899  69.047 1.00 85.45  ? 417 ASP A CB  1 
ATOM   3133  C CG  . ASP A 1 409 ? -0.353  91.192  69.079 1.00 105.43 ? 417 ASP A CG  1 
ATOM   3134  O OD1 . ASP A 1 409 ? 0.022   92.281  69.561 1.00 102.13 ? 417 ASP A OD1 1 
ATOM   3135  O OD2 . ASP A 1 409 ? 0.422   90.345  68.618 1.00 106.23 ? 417 ASP A OD2 1 
ATOM   3136  N N   . PHE A 1 410 ? -4.500  89.753  70.223 1.00 106.83 ? 418 PHE A N   1 
ATOM   3137  C CA  . PHE A 1 410 ? -5.911  89.399  70.098 1.00 110.82 ? 418 PHE A CA  1 
ATOM   3138  C C   . PHE A 1 410 ? -6.712  89.970  71.267 1.00 97.02  ? 418 PHE A C   1 
ATOM   3139  O O   . PHE A 1 410 ? -7.930  90.099  71.188 1.00 116.41 ? 418 PHE A O   1 
ATOM   3140  C CB  . PHE A 1 410 ? -6.191  87.885  69.957 1.00 102.26 ? 418 PHE A CB  1 
ATOM   3141  C CG  . PHE A 1 410 ? -6.386  87.573  68.484 1.00 99.00  ? 418 PHE A CG  1 
ATOM   3142  C CD1 . PHE A 1 410 ? -7.616  87.818  67.878 1.00 96.72  ? 418 PHE A CD1 1 
ATOM   3143  C CD2 . PHE A 1 410 ? -5.317  87.174  67.681 1.00 93.35  ? 418 PHE A CD2 1 
ATOM   3144  C CE1 . PHE A 1 410 ? -7.753  87.685  66.512 1.00 97.50  ? 418 PHE A CE1 1 
ATOM   3145  C CE2 . PHE A 1 410 ? -5.463  87.003  66.312 1.00 83.86  ? 418 PHE A CE2 1 
ATOM   3146  C CZ  . PHE A 1 410 ? -6.687  87.265  65.740 1.00 111.04 ? 418 PHE A CZ  1 
ATOM   3147  N N   . GLN A 1 411 ? -6.026  90.227  72.381 1.00 79.91  ? 419 GLN A N   1 
ATOM   3148  C CA  . GLN A 1 411 ? -6.720  90.696  73.571 1.00 98.51  ? 419 GLN A CA  1 
ATOM   3149  C C   . GLN A 1 411 ? -7.012  92.175  73.332 1.00 107.60 ? 419 GLN A C   1 
ATOM   3150  O O   . GLN A 1 411 ? -8.076  92.670  73.717 1.00 93.52  ? 419 GLN A O   1 
ATOM   3151  C CB  . GLN A 1 411 ? -5.978  90.341  74.868 1.00 100.81 ? 419 GLN A CB  1 
ATOM   3152  C CG  . GLN A 1 411 ? -5.469  88.903  74.814 1.00 155.96 ? 419 GLN A CG  1 
ATOM   3153  C CD  . GLN A 1 411 ? -5.299  88.135  76.094 1.00 141.18 ? 419 GLN A CD  1 
ATOM   3154  O OE1 . GLN A 1 411 ? -6.288  87.693  76.702 1.00 104.39 ? 419 GLN A OE1 1 
ATOM   3155  N NE2 . GLN A 1 411 ? -4.035  87.838  76.396 1.00 107.35 ? 419 GLN A NE2 1 
ATOM   3156  N N   . LYS A 1 412 ? -6.059  92.845  72.653 1.00 75.39  ? 420 LYS A N   1 
ATOM   3157  C CA  . LYS A 1 412 ? -6.175  94.265  72.405 1.00 78.08  ? 420 LYS A CA  1 
ATOM   3158  C C   . LYS A 1 412 ? -7.349  94.403  71.448 1.00 108.79 ? 420 LYS A C   1 
ATOM   3159  O O   . LYS A 1 412 ? -8.101  95.377  71.494 1.00 122.88 ? 420 LYS A O   1 
ATOM   3160  C CB  . LYS A 1 412 ? -4.855  94.840  71.871 1.00 74.10  ? 420 LYS A CB  1 
ATOM   3161  C CG  . LYS A 1 412 ? -4.836  96.298  71.357 1.00 68.45  ? 420 LYS A CG  1 
ATOM   3162  C CD  . LYS A 1 412 ? -3.374  96.573  70.970 1.00 77.02  ? 420 LYS A CD  1 
ATOM   3163  C CE  . LYS A 1 412 ? -2.833  97.975  70.857 1.00 90.22  ? 420 LYS A CE  1 
ATOM   3164  N NZ  . LYS A 1 412 ? -1.375  97.818  70.773 1.00 80.46  ? 420 LYS A NZ  1 
ATOM   3165  N N   . VAL A 1 413 ? -7.500  93.392  70.587 1.00 115.47 ? 421 VAL A N   1 
ATOM   3166  C CA  . VAL A 1 413 ? -8.534  93.419  69.571 1.00 102.00 ? 421 VAL A CA  1 
ATOM   3167  C C   . VAL A 1 413 ? -9.887  93.324  70.263 1.00 108.99 ? 421 VAL A C   1 
ATOM   3168  O O   . VAL A 1 413 ? -10.788 94.109  69.976 1.00 93.53  ? 421 VAL A O   1 
ATOM   3169  C CB  . VAL A 1 413 ? -8.327  92.337  68.504 1.00 80.95  ? 421 VAL A CB  1 
ATOM   3170  C CG1 . VAL A 1 413 ? -9.452  92.417  67.494 1.00 64.88  ? 421 VAL A CG1 1 
ATOM   3171  C CG2 . VAL A 1 413 ? -7.032  92.573  67.735 1.00 79.54  ? 421 VAL A CG2 1 
ATOM   3172  N N   . ALA A 1 414 ? -9.983  92.385  71.206 1.00 106.63 ? 422 ALA A N   1 
ATOM   3173  C CA  . ALA A 1 414 ? -11.197 92.180  71.989 1.00 110.40 ? 422 ALA A CA  1 
ATOM   3174  C C   . ALA A 1 414 ? -11.628 93.499  72.636 1.00 118.33 ? 422 ALA A C   1 
ATOM   3175  O O   . ALA A 1 414 ? -12.819 93.813  72.704 1.00 111.27 ? 422 ALA A O   1 
ATOM   3176  C CB  . ALA A 1 414 ? -10.976 91.101  73.024 1.00 92.39  ? 422 ALA A CB  1 
ATOM   3177  N N   . HIS A 1 415 ? -10.643 94.303  73.036 1.00 98.50  ? 423 HIS A N   1 
ATOM   3178  C CA  . HIS A 1 415 ? -10.934 95.576  73.673 1.00 105.28 ? 423 HIS A CA  1 
ATOM   3179  C C   . HIS A 1 415 ? -11.465 96.578  72.644 1.00 113.15 ? 423 HIS A C   1 
ATOM   3180  O O   . HIS A 1 415 ? -12.369 97.370  72.953 1.00 99.12  ? 423 HIS A O   1 
ATOM   3181  C CB  . HIS A 1 415 ? -9.703  96.075  74.450 1.00 90.73  ? 423 HIS A CB  1 
ATOM   3182  C CG  . HIS A 1 415 ? -9.183  95.194  75.545 1.00 91.94  ? 423 HIS A CG  1 
ATOM   3183  N ND1 . HIS A 1 415 ? -9.970  94.701  76.574 1.00 109.46 ? 423 HIS A ND1 1 
ATOM   3184  C CD2 . HIS A 1 415 ? -7.938  94.756  75.787 1.00 86.59  ? 423 HIS A CD2 1 
ATOM   3185  C CE1 . HIS A 1 415 ? -9.235  93.960  77.397 1.00 83.68  ? 423 HIS A CE1 1 
ATOM   3186  N NE2 . HIS A 1 415 ? -7.995  93.991  76.929 1.00 105.69 ? 423 HIS A NE2 1 
ATOM   3187  N N   . PHE A 1 416 ? -10.865 96.560  71.434 1.00 97.92  ? 424 PHE A N   1 
ATOM   3188  C CA  . PHE A 1 416 ? -11.322 97.456  70.386 1.00 102.27 ? 424 PHE A CA  1 
ATOM   3189  C C   . PHE A 1 416 ? -12.758 97.087  69.983 1.00 105.00 ? 424 PHE A C   1 
ATOM   3190  O O   . PHE A 1 416 ? -13.629 97.955  69.811 1.00 83.94  ? 424 PHE A O   1 
ATOM   3191  C CB  . PHE A 1 416 ? -10.349 97.349  69.223 1.00 84.93  ? 424 PHE A CB  1 
ATOM   3192  C CG  . PHE A 1 416 ? -9.105  98.202  69.321 1.00 109.44 ? 424 PHE A CG  1 
ATOM   3193  C CD1 . PHE A 1 416 ? -9.182  99.493  69.827 1.00 125.31 ? 424 PHE A CD1 1 
ATOM   3194  C CD2 . PHE A 1 416 ? -7.928  97.796  68.698 1.00 129.89 ? 424 PHE A CD2 1 
ATOM   3195  C CE1 . PHE A 1 416 ? -8.062  100.322 69.784 1.00 152.87 ? 424 PHE A CE1 1 
ATOM   3196  C CE2 . PHE A 1 416 ? -6.809  98.614  68.669 1.00 128.62 ? 424 PHE A CE2 1 
ATOM   3197  C CZ  . PHE A 1 416 ? -6.884  99.880  69.206 1.00 149.45 ? 424 PHE A CZ  1 
ATOM   3198  N N   . ILE A 1 417 ? -13.010 95.775  69.880 1.00 84.21  ? 425 ILE A N   1 
ATOM   3199  C CA  . ILE A 1 417 ? -14.352 95.278  69.627 1.00 90.72  ? 425 ILE A CA  1 
ATOM   3200  C C   . ILE A 1 417 ? -15.297 95.834  70.689 1.00 83.56  ? 425 ILE A C   1 
ATOM   3201  O O   . ILE A 1 417 ? -16.363 96.336  70.334 1.00 68.85  ? 425 ILE A O   1 
ATOM   3202  C CB  . ILE A 1 417 ? -14.367 93.742  69.559 1.00 80.31  ? 425 ILE A CB  1 
ATOM   3203  C CG1 . ILE A 1 417 ? -13.640 93.233  68.280 1.00 68.94  ? 425 ILE A CG1 1 
ATOM   3204  C CG2 . ILE A 1 417 ? -15.788 93.199  69.763 1.00 59.91  ? 425 ILE A CG2 1 
ATOM   3205  C CD1 . ILE A 1 417 ? -13.315 91.738  68.307 1.00 78.25  ? 425 ILE A CD1 1 
ATOM   3206  N N   . HIS A 1 418 ? -14.858 95.777  71.959 1.00 74.58  ? 426 HIS A N   1 
ATOM   3207  C CA  . HIS A 1 418 ? -15.715 96.229  73.034 1.00 80.10  ? 426 HIS A CA  1 
ATOM   3208  C C   . HIS A 1 418 ? -16.124 97.688  72.806 1.00 79.60  ? 426 HIS A C   1 
ATOM   3209  O O   . HIS A 1 418 ? -17.319 98.026  72.855 1.00 65.96  ? 426 HIS A O   1 
ATOM   3210  C CB  . HIS A 1 418 ? -15.138 95.987  74.435 1.00 88.35  ? 426 HIS A CB  1 
ATOM   3211  C CG  . HIS A 1 418 ? -16.115 96.563  75.433 1.00 110.60 ? 426 HIS A CG  1 
ATOM   3212  N ND1 . HIS A 1 418 ? -17.390 96.021  75.546 1.00 123.47 ? 426 HIS A ND1 1 
ATOM   3213  C CD2 . HIS A 1 418 ? -16.099 97.657  76.262 1.00 87.31  ? 426 HIS A CD2 1 
ATOM   3214  C CE1 . HIS A 1 418 ? -18.101 96.744  76.432 1.00 105.57 ? 426 HIS A CE1 1 
ATOM   3215  N NE2 . HIS A 1 418 ? -17.337 97.743  76.875 1.00 90.77  ? 426 HIS A NE2 1 
ATOM   3216  N N   . ARG A 1 419 ? -15.141 98.561  72.551 1.00 67.06  ? 427 ARG A N   1 
ATOM   3217  C CA  . ARG A 1 419 ? -15.489 99.950  72.251 1.00 91.07  ? 427 ARG A CA  1 
ATOM   3218  C C   . ARG A 1 419 ? -16.539 100.033 71.122 1.00 107.98 ? 427 ARG A C   1 
ATOM   3219  O O   . ARG A 1 419 ? -17.574 100.725 71.232 1.00 85.09  ? 427 ARG A O   1 
ATOM   3220  C CB  . ARG A 1 419 ? -14.301 100.807 71.796 1.00 82.79  ? 427 ARG A CB  1 
ATOM   3221  C CG  . ARG A 1 419 ? -12.908 100.683 72.363 1.00 73.68  ? 427 ARG A CG  1 
ATOM   3222  C CD  . ARG A 1 419 ? -12.680 101.362 73.695 1.00 85.59  ? 427 ARG A CD  1 
ATOM   3223  N NE  . ARG A 1 419 ? -11.279 101.729 73.511 1.00 71.78  ? 427 ARG A NE  1 
ATOM   3224  C CZ  . ARG A 1 419 ? -10.930 102.711 72.644 1.00 90.60  ? 427 ARG A CZ  1 
ATOM   3225  N NH1 . ARG A 1 419 ? -11.841 103.685 72.368 1.00 58.15  ? 427 ARG A NH1 1 
ATOM   3226  N NH2 . ARG A 1 419 ? -9.659  102.734 72.171 1.00 74.28  ? 427 ARG A NH2 1 
ATOM   3227  N N   . GLY A 1 420 ? -16.274 99.305  70.022 1.00 91.83  ? 428 GLY A N   1 
ATOM   3228  C CA  . GLY A 1 420 ? -17.293 99.154  69.001 1.00 90.15  ? 428 GLY A CA  1 
ATOM   3229  C C   . GLY A 1 420 ? -18.694 98.890  69.588 1.00 83.47  ? 428 GLY A C   1 
ATOM   3230  O O   . GLY A 1 420 ? -19.662 99.551  69.237 1.00 64.97  ? 428 GLY A O   1 
ATOM   3231  N N   . ILE A 1 421 ? -18.821 97.920  70.491 1.00 72.39  ? 429 ILE A N   1 
ATOM   3232  C CA  . ILE A 1 421 ? -20.092 97.503  71.067 1.00 86.88  ? 429 ILE A CA  1 
ATOM   3233  C C   . ILE A 1 421 ? -20.737 98.638  71.867 1.00 100.41 ? 429 ILE A C   1 
ATOM   3234  O O   . ILE A 1 421 ? -21.972 98.806  71.847 1.00 89.63  ? 429 ILE A O   1 
ATOM   3235  C CB  . ILE A 1 421 ? -19.899 96.210  71.896 1.00 73.49  ? 429 ILE A CB  1 
ATOM   3236  C CG1 . ILE A 1 421 ? -19.340 95.073  71.027 1.00 66.61  ? 429 ILE A CG1 1 
ATOM   3237  C CG2 . ILE A 1 421 ? -21.200 95.797  72.587 1.00 58.94  ? 429 ILE A CG2 1 
ATOM   3238  C CD1 . ILE A 1 421 ? -20.086 94.840  69.695 1.00 58.77  ? 429 ILE A CD1 1 
ATOM   3239  N N   . GLU A 1 422 ? -19.879 99.386  72.585 1.00 94.01  ? 430 GLU A N   1 
ATOM   3240  C CA  . GLU A 1 422 ? -20.338 100.495 73.401 1.00 102.94 ? 430 GLU A CA  1 
ATOM   3241  C C   . GLU A 1 422 ? -21.017 101.512 72.479 1.00 111.45 ? 430 GLU A C   1 
ATOM   3242  O O   . GLU A 1 422 ? -22.137 101.987 72.777 1.00 77.98  ? 430 GLU A O   1 
ATOM   3243  C CB  . GLU A 1 422 ? -19.166 101.119 74.162 1.00 91.75  ? 430 GLU A CB  1 
ATOM   3244  C CG  . GLU A 1 422 ? -18.656 100.293 75.342 1.00 112.30 ? 430 GLU A CG  1 
ATOM   3245  C CD  . GLU A 1 422 ? -17.629 101.074 76.154 1.00 114.72 ? 430 GLU A CD  1 
ATOM   3246  O OE1 . GLU A 1 422 ? -17.012 102.010 75.518 1.00 84.74  ? 430 GLU A OE1 1 
ATOM   3247  O OE2 . GLU A 1 422 ? -17.437 100.722 77.381 1.00 83.75  ? 430 GLU A OE2 1 
ATOM   3248  N N   . LEU A 1 423 ? -20.312 101.819 71.366 1.00 76.49  ? 431 LEU A N   1 
ATOM   3249  C CA  . LEU A 1 423 ? -20.814 102.798 70.413 1.00 86.00  ? 431 LEU A CA  1 
ATOM   3250  C C   . LEU A 1 423 ? -22.141 102.296 69.844 1.00 98.88  ? 431 LEU A C   1 
ATOM   3251  O O   . LEU A 1 423 ? -23.143 103.026 69.792 1.00 88.05  ? 431 LEU A O   1 
ATOM   3252  C CB  . LEU A 1 423 ? -19.791 102.974 69.301 1.00 76.45  ? 431 LEU A CB  1 
ATOM   3253  C CG  . LEU A 1 423 ? -18.757 104.072 69.529 1.00 84.28  ? 431 LEU A CG  1 
ATOM   3254  C CD1 . LEU A 1 423 ? -17.749 104.104 68.398 1.00 89.38  ? 431 LEU A CD1 1 
ATOM   3255  C CD2 . LEU A 1 423 ? -19.553 105.354 69.541 1.00 104.14 ? 431 LEU A CD2 1 
ATOM   3256  N N   . THR A 1 424 ? -22.160 101.000 69.509 1.00 82.60  ? 432 THR A N   1 
ATOM   3257  C CA  . THR A 1 424 ? -23.374 100.379 69.020 1.00 102.91 ? 432 THR A CA  1 
ATOM   3258  C C   . THR A 1 424 ? -24.525 100.721 69.962 1.00 104.28 ? 432 THR A C   1 
ATOM   3259  O O   . THR A 1 424 ? -25.562 101.213 69.509 1.00 78.24  ? 432 THR A O   1 
ATOM   3260  C CB  . THR A 1 424 ? -23.146 98.877  68.910 1.00 119.15 ? 432 THR A CB  1 
ATOM   3261  O OG1 . THR A 1 424 ? -22.027 99.009  68.050 1.00 128.23 ? 432 THR A OG1 1 
ATOM   3262  C CG2 . THR A 1 424 ? -24.300 98.150  68.246 1.00 124.68 ? 432 THR A CG2 1 
ATOM   3263  N N   . LEU A 1 425 ? -24.284 100.529 71.267 1.00 88.23  ? 433 LEU A N   1 
ATOM   3264  C CA  . LEU A 1 425 ? -25.333 100.702 72.252 1.00 84.88  ? 433 LEU A CA  1 
ATOM   3265  C C   . LEU A 1 425 ? -25.765 102.162 72.343 1.00 104.12 ? 433 LEU A C   1 
ATOM   3266  O O   . LEU A 1 425 ? -26.968 102.448 72.498 1.00 99.60  ? 433 LEU A O   1 
ATOM   3267  C CB  . LEU A 1 425 ? -24.779 100.185 73.569 1.00 70.28  ? 433 LEU A CB  1 
ATOM   3268  C CG  . LEU A 1 425 ? -24.902 98.676  73.694 1.00 72.84  ? 433 LEU A CG  1 
ATOM   3269  C CD1 . LEU A 1 425 ? -23.759 97.978  74.449 1.00 52.58  ? 433 LEU A CD1 1 
ATOM   3270  C CD2 . LEU A 1 425 ? -26.313 98.523  74.295 1.00 57.81  ? 433 LEU A CD2 1 
ATOM   3271  N N   . GLN A 1 426 ? -24.772 103.067 72.270 1.00 75.62  ? 434 GLN A N   1 
ATOM   3272  C CA  . GLN A 1 426 ? -25.040 104.489 72.352 1.00 71.77  ? 434 GLN A CA  1 
ATOM   3273  C C   . GLN A 1 426 ? -26.026 104.872 71.250 1.00 91.86  ? 434 GLN A C   1 
ATOM   3274  O O   . GLN A 1 426 ? -27.067 105.500 71.485 1.00 99.52  ? 434 GLN A O   1 
ATOM   3275  C CB  . GLN A 1 426 ? -23.738 105.234 72.085 1.00 66.72  ? 434 GLN A CB  1 
ATOM   3276  C CG  . GLN A 1 426 ? -22.708 105.110 73.189 1.00 87.34  ? 434 GLN A CG  1 
ATOM   3277  C CD  . GLN A 1 426 ? -21.476 105.877 72.797 1.00 91.32  ? 434 GLN A CD  1 
ATOM   3278  O OE1 . GLN A 1 426 ? -21.599 106.979 72.262 1.00 73.85  ? 434 GLN A OE1 1 
ATOM   3279  N NE2 . GLN A 1 426 ? -20.298 105.332 73.062 1.00 116.47 ? 434 GLN A NE2 1 
ATOM   3280  N N   . ILE A 1 427 ? -25.626 104.548 70.018 1.00 77.52  ? 435 ILE A N   1 
ATOM   3281  C CA  . ILE A 1 427 ? -26.463 104.857 68.886 1.00 71.14  ? 435 ILE A CA  1 
ATOM   3282  C C   . ILE A 1 427 ? -27.862 104.236 69.027 1.00 83.56  ? 435 ILE A C   1 
ATOM   3283  O O   . ILE A 1 427 ? -28.846 104.917 68.761 1.00 100.77 ? 435 ILE A O   1 
ATOM   3284  C CB  . ILE A 1 427 ? -25.723 104.408 67.628 1.00 83.86  ? 435 ILE A CB  1 
ATOM   3285  C CG1 . ILE A 1 427 ? -24.297 105.004 67.672 1.00 97.51  ? 435 ILE A CG1 1 
ATOM   3286  C CG2 . ILE A 1 427 ? -26.530 104.788 66.368 1.00 111.65 ? 435 ILE A CG2 1 
ATOM   3287  C CD1 . ILE A 1 427 ? -23.362 104.495 66.590 1.00 108.92 ? 435 ILE A CD1 1 
ATOM   3288  N N   . GLN A 1 428 ? -27.946 102.945 69.388 1.00 70.44  ? 436 GLN A N   1 
ATOM   3289  C CA  . GLN A 1 428 ? -29.174 102.183 69.571 1.00 75.87  ? 436 GLN A CA  1 
ATOM   3290  C C   . GLN A 1 428 ? -30.124 102.874 70.546 1.00 89.13  ? 436 GLN A C   1 
ATOM   3291  O O   . GLN A 1 428 ? -31.340 102.888 70.321 1.00 129.58 ? 436 GLN A O   1 
ATOM   3292  C CB  . GLN A 1 428 ? -28.772 100.765 69.979 1.00 76.23  ? 436 GLN A CB  1 
ATOM   3293  C CG  . GLN A 1 428 ? -29.838 99.923  70.688 1.00 74.04  ? 436 GLN A CG  1 
ATOM   3294  C CD  . GLN A 1 428 ? -29.400 98.492  70.902 1.00 77.10  ? 436 GLN A CD  1 
ATOM   3295  O OE1 . GLN A 1 428 ? -28.479 98.202  71.669 1.00 98.51  ? 436 GLN A OE1 1 
ATOM   3296  N NE2 . GLN A 1 428 ? -30.039 97.564  70.213 1.00 68.98  ? 436 GLN A NE2 1 
ATOM   3297  N N   . SER A 1 429 ? -29.594 103.410 71.652 1.00 71.63  ? 437 SER A N   1 
ATOM   3298  C CA  . SER A 1 429 ? -30.461 104.004 72.661 1.00 100.02 ? 437 SER A CA  1 
ATOM   3299  C C   . SER A 1 429 ? -31.088 105.310 72.140 1.00 92.37  ? 437 SER A C   1 
ATOM   3300  O O   . SER A 1 429 ? -32.295 105.523 72.313 1.00 100.52 ? 437 SER A O   1 
ATOM   3301  C CB  . SER A 1 429 ? -29.759 104.156 73.980 1.00 92.72  ? 437 SER A CB  1 
ATOM   3302  O OG  . SER A 1 429 ? -28.778 105.159 73.791 1.00 102.75 ? 437 SER A OG  1 
ATOM   3303  N N   . ASP A 1 430 ? -30.310 106.095 71.377 1.00 73.86  ? 438 ASP A N   1 
ATOM   3304  C CA  . ASP A 1 430 ? -30.825 107.261 70.663 1.00 77.22  ? 438 ASP A CA  1 
ATOM   3305  C C   . ASP A 1 430 ? -31.714 106.822 69.494 1.00 128.06 ? 438 ASP A C   1 
ATOM   3306  O O   . ASP A 1 430 ? -32.694 107.482 69.155 1.00 150.92 ? 438 ASP A O   1 
ATOM   3307  C CB  . ASP A 1 430 ? -29.727 108.043 69.977 1.00 66.82  ? 438 ASP A CB  1 
ATOM   3308  C CG  . ASP A 1 430 ? -28.419 108.195 70.727 1.00 73.58  ? 438 ASP A CG  1 
ATOM   3309  O OD1 . ASP A 1 430 ? -28.387 107.854 71.966 1.00 66.28  ? 438 ASP A OD1 1 
ATOM   3310  O OD2 . ASP A 1 430 ? -27.474 108.634 70.032 1.00 57.16  ? 438 ASP A OD2 1 
ATOM   3311  N N   . THR A 1 431 ? -31.348 105.699 68.865 1.00 148.36 ? 439 THR A N   1 
ATOM   3312  C CA  . THR A 1 431 ? -32.243 105.046 67.924 1.00 115.39 ? 439 THR A CA  1 
ATOM   3313  C C   . THR A 1 431 ? -33.575 104.802 68.624 1.00 106.04 ? 439 THR A C   1 
ATOM   3314  O O   . THR A 1 431 ? -34.588 104.741 67.958 1.00 96.84  ? 439 THR A O   1 
ATOM   3315  C CB  . THR A 1 431 ? -31.553 103.774 67.418 1.00 150.05 ? 439 THR A CB  1 
ATOM   3316  O OG1 . THR A 1 431 ? -31.079 104.147 66.127 1.00 193.94 ? 439 THR A OG1 1 
ATOM   3317  C CG2 . THR A 1 431 ? -32.438 102.529 67.357 1.00 110.04 ? 439 THR A CG2 1 
ATOM   3318  N N   . GLY A 1 432 ? -33.555 104.730 69.973 1.00 116.09 ? 440 GLY A N   1 
ATOM   3319  C CA  . GLY A 1 432 ? -34.733 104.652 70.823 1.00 115.49 ? 440 GLY A CA  1 
ATOM   3320  C C   . GLY A 1 432 ? -35.221 103.212 70.994 1.00 115.43 ? 440 GLY A C   1 
ATOM   3321  O O   . GLY A 1 432 ? -34.647 102.272 70.410 1.00 87.39  ? 440 GLY A O   1 
ATOM   3322  N N   . VAL A 1 433 ? -36.299 103.072 71.789 1.00 119.84 ? 441 VAL A N   1 
ATOM   3323  C CA  . VAL A 1 433 ? -36.936 101.792 72.102 1.00 146.81 ? 441 VAL A CA  1 
ATOM   3324  C C   . VAL A 1 433 ? -37.353 101.051 70.811 1.00 161.24 ? 441 VAL A C   1 
ATOM   3325  O O   . VAL A 1 433 ? -37.497 99.831  70.823 1.00 203.59 ? 441 VAL A O   1 
ATOM   3326  C CB  . VAL A 1 433 ? -37.999 101.848 73.244 1.00 143.17 ? 441 VAL A CB  1 
ATOM   3327  C CG1 . VAL A 1 433 ? -39.003 100.695 73.223 1.00 114.86 ? 441 VAL A CG1 1 
ATOM   3328  C CG2 . VAL A 1 433 ? -37.403 101.973 74.658 1.00 99.47  ? 441 VAL A CG2 1 
ATOM   3329  N N   . ALA A 1 434 ? -37.507 101.760 69.675 1.00 152.68 ? 442 ALA A N   1 
ATOM   3330  C CA  . ALA A 1 434 ? -37.819 101.191 68.369 1.00 147.55 ? 442 ALA A CA  1 
ATOM   3331  C C   . ALA A 1 434 ? -36.701 101.462 67.350 1.00 138.92 ? 442 ALA A C   1 
ATOM   3332  O O   . ALA A 1 434 ? -35.535 101.629 67.711 1.00 136.18 ? 442 ALA A O   1 
ATOM   3333  C CB  . ALA A 1 434 ? -39.143 101.738 67.859 1.00 30.00  ? 442 ALA A CB  1 
ATOM   3334  N N   . ALA A 1 435 ? -37.085 101.554 66.069 1.00 114.78 ? 443 ALA A N   1 
ATOM   3335  C CA  . ALA A 1 435 ? -36.320 102.108 64.945 1.00 101.49 ? 443 ALA A CA  1 
ATOM   3336  C C   . ALA A 1 435 ? -35.563 101.037 64.168 1.00 104.91 ? 443 ALA A C   1 
ATOM   3337  O O   . ALA A 1 435 ? -34.848 100.237 64.756 1.00 131.63 ? 443 ALA A O   1 
ATOM   3338  C CB  . ALA A 1 435 ? -35.427 103.291 65.275 1.00 58.67  ? 443 ALA A CB  1 
ATOM   3339  N N   . THR A 1 436 ? -35.736 101.084 62.843 1.00 94.12  ? 444 THR A N   1 
ATOM   3340  C CA  . THR A 1 436 ? -35.145 100.204 61.848 1.00 117.55 ? 444 THR A CA  1 
ATOM   3341  C C   . THR A 1 436 ? -33.606 100.261 61.842 1.00 107.55 ? 444 THR A C   1 
ATOM   3342  O O   . THR A 1 436 ? -32.939 101.215 62.294 1.00 79.21  ? 444 THR A O   1 
ATOM   3343  C CB  . THR A 1 436 ? -35.674 100.510 60.432 1.00 128.44 ? 444 THR A CB  1 
ATOM   3344  O OG1 . THR A 1 436 ? -35.320 101.847 60.090 1.00 150.78 ? 444 THR A OG1 1 
ATOM   3345  C CG2 . THR A 1 436 ? -37.167 100.339 60.228 1.00 116.90 ? 444 THR A CG2 1 
ATOM   3346  N N   . LEU A 1 437 ? -33.049 99.194  61.264 1.00 103.19 ? 445 LEU A N   1 
ATOM   3347  C CA  . LEU A 1 437 ? -31.613 99.128  61.122 1.00 97.51  ? 445 LEU A CA  1 
ATOM   3348  C C   . LEU A 1 437 ? -31.152 100.258 60.200 1.00 113.70 ? 445 LEU A C   1 
ATOM   3349  O O   . LEU A 1 437 ? -29.964 100.651 60.258 1.00 72.56  ? 445 LEU A O   1 
ATOM   3350  C CB  . LEU A 1 437 ? -31.148 97.748  60.660 1.00 85.44  ? 445 LEU A CB  1 
ATOM   3351  C CG  . LEU A 1 437 ? -29.637 97.602  60.430 1.00 88.09  ? 445 LEU A CG  1 
ATOM   3352  C CD1 . LEU A 1 437 ? -28.795 98.127  61.568 1.00 127.36 ? 445 LEU A CD1 1 
ATOM   3353  C CD2 . LEU A 1 437 ? -29.218 96.138  60.225 1.00 87.66  ? 445 LEU A CD2 1 
ATOM   3354  N N   . LYS A 1 438 ? -32.094 100.737 59.360 1.00 122.80 ? 446 LYS A N   1 
ATOM   3355  C CA  . LYS A 1 438 ? -31.888 101.817 58.405 1.00 111.56 ? 446 LYS A CA  1 
ATOM   3356  C C   . LYS A 1 438 ? -31.655 103.103 59.191 1.00 97.21  ? 446 LYS A C   1 
ATOM   3357  O O   . LYS A 1 438 ? -30.662 103.778 58.959 1.00 110.79 ? 446 LYS A O   1 
ATOM   3358  C CB  . LYS A 1 438 ? -32.978 101.897 57.330 1.00 91.45  ? 446 LYS A CB  1 
ATOM   3359  C CG  . LYS A 1 438 ? -32.728 103.057 56.369 1.00 91.91  ? 446 LYS A CG  1 
ATOM   3360  C CD  . LYS A 1 438 ? -33.718 103.331 55.246 1.00 103.92 ? 446 LYS A CD  1 
ATOM   3361  C CE  . LYS A 1 438 ? -33.293 104.582 54.517 1.00 121.12 ? 446 LYS A CE  1 
ATOM   3362  N NZ  . LYS A 1 438 ? -33.920 104.856 53.213 1.00 120.24 ? 446 LYS A NZ  1 
ATOM   3363  N N   . GLU A 1 439 ? -32.593 103.437 60.085 1.00 100.51 ? 447 GLU A N   1 
ATOM   3364  C CA  . GLU A 1 439 ? -32.521 104.595 60.974 1.00 97.82  ? 447 GLU A CA  1 
ATOM   3365  C C   . GLU A 1 439 ? -31.215 104.577 61.777 1.00 107.52 ? 447 GLU A C   1 
ATOM   3366  O O   . GLU A 1 439 ? -30.558 105.618 61.923 1.00 75.28  ? 447 GLU A O   1 
ATOM   3367  C CB  . GLU A 1 439 ? -33.737 104.613 61.897 1.00 104.29 ? 447 GLU A CB  1 
ATOM   3368  C CG  . GLU A 1 439 ? -35.023 105.113 61.237 1.00 122.60 ? 447 GLU A CG  1 
ATOM   3369  C CD  . GLU A 1 439 ? -36.267 104.678 62.001 1.00 137.28 ? 447 GLU A CD  1 
ATOM   3370  O OE1 . GLU A 1 439 ? -36.908 105.447 62.743 1.00 119.94 ? 447 GLU A OE1 1 
ATOM   3371  O OE2 . GLU A 1 439 ? -36.596 103.482 61.900 1.00 167.42 ? 447 GLU A OE2 1 
ATOM   3372  N N   . PHE A 1 440 ? -30.874 103.394 62.330 1.00 103.63 ? 448 PHE A N   1 
ATOM   3373  C CA  . PHE A 1 440 ? -29.593 103.181 62.993 1.00 93.84  ? 448 PHE A CA  1 
ATOM   3374  C C   . PHE A 1 440 ? -28.395 103.597 62.113 1.00 91.12  ? 448 PHE A C   1 
ATOM   3375  O O   . PHE A 1 440 ? -27.515 104.296 62.609 1.00 91.46  ? 448 PHE A O   1 
ATOM   3376  C CB  . PHE A 1 440 ? -29.494 101.734 63.484 1.00 99.53  ? 448 PHE A CB  1 
ATOM   3377  C CG  . PHE A 1 440 ? -28.199 101.421 64.232 1.00 84.78  ? 448 PHE A CG  1 
ATOM   3378  C CD1 . PHE A 1 440 ? -27.035 101.037 63.559 1.00 93.29  ? 448 PHE A CD1 1 
ATOM   3379  C CD2 . PHE A 1 440 ? -28.139 101.559 65.603 1.00 67.51  ? 448 PHE A CD2 1 
ATOM   3380  C CE1 . PHE A 1 440 ? -25.859 100.775 64.248 1.00 100.59 ? 448 PHE A CE1 1 
ATOM   3381  C CE2 . PHE A 1 440 ? -26.970 101.310 66.289 1.00 75.20  ? 448 PHE A CE2 1 
ATOM   3382  C CZ  . PHE A 1 440 ? -25.841 100.895 65.626 1.00 103.57 ? 448 PHE A CZ  1 
ATOM   3383  N N   . LYS A 1 441 ? -28.325 103.136 60.846 1.00 61.46  ? 449 LYS A N   1 
ATOM   3384  C CA  . LYS A 1 441 ? -27.251 103.472 59.923 1.00 80.08  ? 449 LYS A CA  1 
ATOM   3385  C C   . LYS A 1 441 ? -27.199 104.979 59.654 1.00 95.79  ? 449 LYS A C   1 
ATOM   3386  O O   . LYS A 1 441 ? -26.122 105.551 59.484 1.00 90.66  ? 449 LYS A O   1 
ATOM   3387  C CB  . LYS A 1 441 ? -27.394 102.661 58.631 1.00 86.47  ? 449 LYS A CB  1 
ATOM   3388  C CG  . LYS A 1 441 ? -26.585 101.352 58.609 1.00 104.53 ? 449 LYS A CG  1 
ATOM   3389  C CD  . LYS A 1 441 ? -26.715 100.439 57.392 1.00 99.98  ? 449 LYS A CD  1 
ATOM   3390  C CE  . LYS A 1 441 ? -27.769 99.408  57.707 1.00 112.92 ? 449 LYS A CE  1 
ATOM   3391  N NZ  . LYS A 1 441 ? -27.724 98.227  56.824 1.00 89.88  ? 449 LYS A NZ  1 
ATOM   3392  N N   . GLU A 1 442 ? -28.374 105.610 59.586 1.00 107.91 ? 450 GLU A N   1 
ATOM   3393  C CA  . GLU A 1 442 ? -28.477 107.039 59.357 1.00 126.78 ? 450 GLU A CA  1 
ATOM   3394  C C   . GLU A 1 442 ? -27.925 107.792 60.563 1.00 140.99 ? 450 GLU A C   1 
ATOM   3395  O O   . GLU A 1 442 ? -27.119 108.706 60.371 1.00 179.57 ? 450 GLU A O   1 
ATOM   3396  C CB  . GLU A 1 442 ? -29.909 107.471 59.053 1.00 121.78 ? 450 GLU A CB  1 
ATOM   3397  C CG  . GLU A 1 442 ? -30.449 106.998 57.713 1.00 134.71 ? 450 GLU A CG  1 
ATOM   3398  C CD  . GLU A 1 442 ? -31.964 107.161 57.667 1.00 145.13 ? 450 GLU A CD  1 
ATOM   3399  O OE1 . GLU A 1 442 ? -32.526 107.949 58.478 1.00 114.18 ? 450 GLU A OE1 1 
ATOM   3400  O OE2 . GLU A 1 442 ? -32.600 106.440 56.847 1.00 152.89 ? 450 GLU A OE2 1 
ATOM   3401  N N   . ARG A 1 443 ? -28.320 107.393 61.785 1.00 104.42 ? 451 ARG A N   1 
ATOM   3402  C CA  . ARG A 1 443 ? -27.827 108.050 62.991 1.00 123.33 ? 451 ARG A CA  1 
ATOM   3403  C C   . ARG A 1 443 ? -26.304 107.883 63.093 1.00 124.93 ? 451 ARG A C   1 
ATOM   3404  O O   . ARG A 1 443 ? -25.598 108.797 63.532 1.00 108.79 ? 451 ARG A O   1 
ATOM   3405  C CB  . ARG A 1 443 ? -28.461 107.474 64.262 1.00 124.60 ? 451 ARG A CB  1 
ATOM   3406  C CG  . ARG A 1 443 ? -28.005 108.282 65.465 1.00 120.42 ? 451 ARG A CG  1 
ATOM   3407  C CD  . ARG A 1 443 ? -28.489 109.731 65.295 1.00 125.27 ? 451 ARG A CD  1 
ATOM   3408  N NE  . ARG A 1 443 ? -29.864 109.828 65.787 1.00 105.54 ? 451 ARG A NE  1 
ATOM   3409  C CZ  . ARG A 1 443 ? -30.242 109.525 67.037 1.00 123.67 ? 451 ARG A CZ  1 
ATOM   3410  N NH1 . ARG A 1 443 ? -29.339 109.370 67.999 1.00 118.41 ? 451 ARG A NH1 1 
ATOM   3411  N NH2 . ARG A 1 443 ? -31.528 109.402 67.336 1.00 126.77 ? 451 ARG A NH2 1 
ATOM   3412  N N   . LEU A 1 444 ? -25.819 106.699 62.676 1.00 112.71 ? 452 LEU A N   1 
ATOM   3413  C CA  . LEU A 1 444 ? -24.409 106.346 62.700 1.00 91.37  ? 452 LEU A CA  1 
ATOM   3414  C C   . LEU A 1 444 ? -23.657 107.295 61.779 1.00 77.91  ? 452 LEU A C   1 
ATOM   3415  O O   . LEU A 1 444 ? -22.564 107.735 62.123 1.00 104.93 ? 452 LEU A O   1 
ATOM   3416  C CB  . LEU A 1 444 ? -24.185 104.871 62.349 1.00 79.35  ? 452 LEU A CB  1 
ATOM   3417  C CG  . LEU A 1 444 ? -22.760 104.385 62.057 1.00 87.29  ? 452 LEU A CG  1 
ATOM   3418  C CD1 . LEU A 1 444 ? -21.745 104.707 63.105 1.00 124.89 ? 452 LEU A CD1 1 
ATOM   3419  C CD2 . LEU A 1 444 ? -22.765 102.865 61.999 1.00 94.84  ? 452 LEU A CD2 1 
ATOM   3420  N N   . ALA A 1 445 ? -24.254 107.612 60.624 1.00 76.57  ? 453 ALA A N   1 
ATOM   3421  C CA  . ALA A 1 445 ? -23.633 108.480 59.629 1.00 90.35  ? 453 ALA A CA  1 
ATOM   3422  C C   . ALA A 1 445 ? -23.727 109.924 60.108 1.00 98.82  ? 453 ALA A C   1 
ATOM   3423  O O   . ALA A 1 445 ? -22.957 110.769 59.651 1.00 95.91  ? 453 ALA A O   1 
ATOM   3424  C CB  . ALA A 1 445 ? -24.275 108.278 58.277 1.00 80.91  ? 453 ALA A CB  1 
ATOM   3425  N N   . GLY A 1 446 ? -24.593 110.128 61.122 1.00 100.73 ? 454 GLY A N   1 
ATOM   3426  C CA  . GLY A 1 446 ? -24.787 111.408 61.790 1.00 127.32 ? 454 GLY A CA  1 
ATOM   3427  C C   . GLY A 1 446 ? -23.461 111.999 62.263 1.00 124.84 ? 454 GLY A C   1 
ATOM   3428  O O   . GLY A 1 446 ? -22.565 111.278 62.728 1.00 105.74 ? 454 GLY A O   1 
ATOM   3429  N N   . ASP A 1 447 ? -23.383 113.330 62.167 1.00 118.29 ? 455 ASP A N   1 
ATOM   3430  C CA  . ASP A 1 447 ? -22.229 114.134 62.559 1.00 117.00 ? 455 ASP A CA  1 
ATOM   3431  C C   . ASP A 1 447 ? -21.698 113.771 63.946 1.00 120.00 ? 455 ASP A C   1 
ATOM   3432  O O   . ASP A 1 447 ? -20.503 113.496 64.131 1.00 118.73 ? 455 ASP A O   1 
ATOM   3433  C CB  . ASP A 1 447 ? -22.572 115.615 62.537 1.00 96.75  ? 455 ASP A CB  1 
ATOM   3434  C CG  . ASP A 1 447 ? -22.154 116.320 61.250 1.00 115.95 ? 455 ASP A CG  1 
ATOM   3435  O OD1 . ASP A 1 447 ? -20.919 116.434 61.039 1.00 104.80 ? 455 ASP A OD1 1 
ATOM   3436  O OD2 . ASP A 1 447 ? -23.054 116.717 60.449 1.00 97.86  ? 455 ASP A OD2 1 
ATOM   3437  N N   . LYS A 1 448 ? -22.620 113.745 64.920 1.00 109.13 ? 456 LYS A N   1 
ATOM   3438  C CA  . LYS A 1 448 ? -22.284 113.479 66.317 1.00 99.85  ? 456 LYS A CA  1 
ATOM   3439  C C   . LYS A 1 448 ? -21.273 112.323 66.373 1.00 116.94 ? 456 LYS A C   1 
ATOM   3440  O O   . LYS A 1 448 ? -20.105 112.449 66.770 1.00 117.89 ? 456 LYS A O   1 
ATOM   3441  C CB  . LYS A 1 448 ? -23.660 113.288 66.977 1.00 88.92  ? 456 LYS A CB  1 
ATOM   3442  C CG  . LYS A 1 448 ? -23.781 113.079 68.484 1.00 108.48 ? 456 LYS A CG  1 
ATOM   3443  C CD  . LYS A 1 448 ? -25.224 113.309 68.924 1.00 95.73  ? 456 LYS A CD  1 
ATOM   3444  C CE  . LYS A 1 448 ? -25.497 112.878 70.348 1.00 105.86 ? 456 LYS A CE  1 
ATOM   3445  N NZ  . LYS A 1 448 ? -25.481 111.442 70.674 1.00 69.57  ? 456 LYS A NZ  1 
ATOM   3446  N N   . TYR A 1 449 ? -21.731 111.206 65.821 1.00 152.15 ? 457 TYR A N   1 
ATOM   3447  C CA  . TYR A 1 449 ? -21.080 109.939 66.071 1.00 133.12 ? 457 TYR A CA  1 
ATOM   3448  C C   . TYR A 1 449 ? -19.887 109.750 65.157 1.00 135.82 ? 457 TYR A C   1 
ATOM   3449  O O   . TYR A 1 449 ? -18.906 109.184 65.616 1.00 113.82 ? 457 TYR A O   1 
ATOM   3450  C CB  . TYR A 1 449 ? -22.132 108.851 65.903 1.00 106.84 ? 457 TYR A CB  1 
ATOM   3451  C CG  . TYR A 1 449 ? -22.911 108.653 67.187 1.00 87.34  ? 457 TYR A CG  1 
ATOM   3452  C CD1 . TYR A 1 449 ? -22.339 107.952 68.249 1.00 86.86  ? 457 TYR A CD1 1 
ATOM   3453  C CD2 . TYR A 1 449 ? -24.218 109.116 67.317 1.00 86.47  ? 457 TYR A CD2 1 
ATOM   3454  C CE1 . TYR A 1 449 ? -23.061 107.656 69.396 1.00 76.26  ? 457 TYR A CE1 1 
ATOM   3455  C CE2 . TYR A 1 449 ? -24.922 108.882 68.487 1.00 96.52  ? 457 TYR A CE2 1 
ATOM   3456  C CZ  . TYR A 1 449 ? -24.341 108.160 69.523 1.00 80.11  ? 457 TYR A CZ  1 
ATOM   3457  O OH  . TYR A 1 449 ? -25.022 107.865 70.650 1.00 74.74  ? 457 TYR A OH  1 
ATOM   3458  N N   . GLN A 1 450 ? -19.991 110.227 63.910 1.00 125.57 ? 458 GLN A N   1 
ATOM   3459  C CA  . GLN A 1 450 ? -18.899 110.151 62.954 1.00 123.15 ? 458 GLN A CA  1 
ATOM   3460  C C   . GLN A 1 450 ? -17.572 110.622 63.562 1.00 117.09 ? 458 GLN A C   1 
ATOM   3461  O O   . GLN A 1 450 ? -16.512 110.073 63.246 1.00 114.10 ? 458 GLN A O   1 
ATOM   3462  C CB  . GLN A 1 450 ? -19.241 110.884 61.657 1.00 132.06 ? 458 GLN A CB  1 
ATOM   3463  C CG  . GLN A 1 450 ? -20.123 110.099 60.683 1.00 115.09 ? 458 GLN A CG  1 
ATOM   3464  C CD  . GLN A 1 450 ? -19.606 108.722 60.316 1.00 121.92 ? 458 GLN A CD  1 
ATOM   3465  O OE1 . GLN A 1 450 ? -20.130 107.689 60.757 1.00 128.55 ? 458 GLN A OE1 1 
ATOM   3466  N NE2 . GLN A 1 450 ? -18.537 108.698 59.538 1.00 142.75 ? 458 GLN A NE2 1 
ATOM   3467  N N   . ALA A 1 451 ? -17.648 111.605 64.469 1.00 96.17  ? 459 ALA A N   1 
ATOM   3468  C CA  . ALA A 1 451 ? -16.483 112.051 65.223 1.00 105.80 ? 459 ALA A CA  1 
ATOM   3469  C C   . ALA A 1 451 ? -15.864 110.922 66.075 1.00 112.01 ? 459 ALA A C   1 
ATOM   3470  O O   . ALA A 1 451 ? -14.669 110.628 65.973 1.00 116.69 ? 459 ALA A O   1 
ATOM   3471  C CB  . ALA A 1 451 ? -16.867 113.278 66.030 1.00 94.52  ? 459 ALA A CB  1 
ATOM   3472  N N   . ALA A 1 452 ? -16.700 110.264 66.891 1.00 124.98 ? 460 ALA A N   1 
ATOM   3473  C CA  . ALA A 1 452 ? -16.295 109.177 67.783 1.00 147.59 ? 460 ALA A CA  1 
ATOM   3474  C C   . ALA A 1 452 ? -15.751 107.998 66.972 1.00 156.22 ? 460 ALA A C   1 
ATOM   3475  O O   . ALA A 1 452 ? -14.728 107.398 67.318 1.00 135.56 ? 460 ALA A O   1 
ATOM   3476  C CB  . ALA A 1 452 ? -17.474 108.726 68.633 1.00 136.16 ? 460 ALA A CB  1 
ATOM   3477  N N   . VAL A 1 453 ? -16.474 107.689 65.891 1.00 162.13 ? 461 VAL A N   1 
ATOM   3478  C CA  . VAL A 1 453 ? -16.138 106.592 65.012 1.00 130.10 ? 461 VAL A CA  1 
ATOM   3479  C C   . VAL A 1 453 ? -14.792 106.838 64.342 1.00 127.42 ? 461 VAL A C   1 
ATOM   3480  O O   . VAL A 1 453 ? -13.988 105.905 64.282 1.00 126.39 ? 461 VAL A O   1 
ATOM   3481  C CB  . VAL A 1 453 ? -17.292 106.266 64.054 1.00 119.28 ? 461 VAL A CB  1 
ATOM   3482  C CG1 . VAL A 1 453 ? -16.843 105.535 62.786 1.00 102.66 ? 461 VAL A CG1 1 
ATOM   3483  C CG2 . VAL A 1 453 ? -18.281 105.408 64.837 1.00 104.93 ? 461 VAL A CG2 1 
ATOM   3484  N N   . GLN A 1 454 ? -14.546 108.090 63.916 1.00 110.17 ? 462 GLN A N   1 
ATOM   3485  C CA  . GLN A 1 454 ? -13.266 108.422 63.298 1.00 113.32 ? 462 GLN A CA  1 
ATOM   3486  C C   . GLN A 1 454 ? -12.128 108.241 64.316 1.00 108.55 ? 462 GLN A C   1 
ATOM   3487  O O   . GLN A 1 454 ? -11.059 107.739 63.985 1.00 91.04  ? 462 GLN A O   1 
ATOM   3488  C CB  . GLN A 1 454 ? -13.189 109.704 62.463 1.00 101.52 ? 462 GLN A CB  1 
ATOM   3489  C CG  . GLN A 1 454 ? -12.375 109.501 61.181 1.00 144.23 ? 462 GLN A CG  1 
ATOM   3490  C CD  . GLN A 1 454 ? -12.133 110.722 60.303 1.00 165.34 ? 462 GLN A CD  1 
ATOM   3491  O OE1 . GLN A 1 454 ? -12.471 111.868 60.632 1.00 159.70 ? 462 GLN A OE1 1 
ATOM   3492  N NE2 . GLN A 1 454 ? -11.497 110.500 59.155 1.00 126.38 ? 462 GLN A NE2 1 
ATOM   3493  N N   . ALA A 1 455 ? -12.371 108.610 65.575 1.00 108.63 ? 463 ALA A N   1 
ATOM   3494  C CA  . ALA A 1 455 ? -11.423 108.380 66.656 1.00 106.73 ? 463 ALA A CA  1 
ATOM   3495  C C   . ALA A 1 455 ? -11.032 106.910 66.718 1.00 111.70 ? 463 ALA A C   1 
ATOM   3496  O O   . ALA A 1 455 ? -9.855  106.554 66.605 1.00 117.85 ? 463 ALA A O   1 
ATOM   3497  C CB  . ALA A 1 455 ? -12.064 108.771 67.972 1.00 91.85  ? 463 ALA A CB  1 
ATOM   3498  N N   . LEU A 1 456 ? -12.043 106.073 66.995 1.00 111.93 ? 464 LEU A N   1 
ATOM   3499  C CA  . LEU A 1 456 ? -11.816 104.652 67.180 1.00 100.19 ? 464 LEU A CA  1 
ATOM   3500  C C   . LEU A 1 456 ? -11.124 104.091 65.930 1.00 102.17 ? 464 LEU A C   1 
ATOM   3501  O O   . LEU A 1 456 ? -10.105 103.395 66.037 1.00 68.25  ? 464 LEU A O   1 
ATOM   3502  C CB  . LEU A 1 456 ? -13.117 103.935 67.518 1.00 79.10  ? 464 LEU A CB  1 
ATOM   3503  C CG  . LEU A 1 456 ? -12.968 102.425 67.776 1.00 94.13  ? 464 LEU A CG  1 
ATOM   3504  C CD1 . LEU A 1 456 ? -11.868 102.192 68.772 1.00 97.77  ? 464 LEU A CD1 1 
ATOM   3505  C CD2 . LEU A 1 456 ? -14.226 101.715 68.313 1.00 107.38 ? 464 LEU A CD2 1 
ATOM   3506  N N   . ARG A 1 457 ? -11.685 104.431 64.757 1.00 93.14  ? 465 ARG A N   1 
ATOM   3507  C CA  . ARG A 1 457 ? -11.181 103.943 63.489 1.00 96.60  ? 465 ARG A CA  1 
ATOM   3508  C C   . ARG A 1 457 ? -9.678  104.195 63.400 1.00 110.41 ? 465 ARG A C   1 
ATOM   3509  O O   . ARG A 1 457 ? -8.923  103.285 63.067 1.00 117.46 ? 465 ARG A O   1 
ATOM   3510  C CB  . ARG A 1 457 ? -11.966 104.568 62.329 1.00 95.82  ? 465 ARG A CB  1 
ATOM   3511  C CG  . ARG A 1 457 ? -11.518 104.069 60.961 1.00 85.08  ? 465 ARG A CG  1 
ATOM   3512  C CD  . ARG A 1 457 ? -12.385 104.708 59.860 1.00 98.43  ? 465 ARG A CD  1 
ATOM   3513  N NE  . ARG A 1 457 ? -11.870 106.067 59.674 1.00 115.77 ? 465 ARG A NE  1 
ATOM   3514  C CZ  . ARG A 1 457 ? -11.018 106.408 58.705 1.00 119.55 ? 465 ARG A CZ  1 
ATOM   3515  N NH1 . ARG A 1 457 ? -11.064 105.781 57.542 1.00 83.07  ? 465 ARG A NH1 1 
ATOM   3516  N NH2 . ARG A 1 457 ? -10.188 107.440 58.855 1.00 121.91 ? 465 ARG A NH2 1 
ATOM   3517  N N   . GLU A 1 458 ? -9.264  105.423 63.735 1.00 112.59 ? 466 GLU A N   1 
ATOM   3518  C CA  . GLU A 1 458 ? -7.875  105.843 63.599 1.00 113.24 ? 466 GLU A CA  1 
ATOM   3519  C C   . GLU A 1 458 ? -6.972  104.961 64.447 1.00 86.53  ? 466 GLU A C   1 
ATOM   3520  O O   . GLU A 1 458 ? -5.968  104.446 63.947 1.00 83.72  ? 466 GLU A O   1 
ATOM   3521  C CB  . GLU A 1 458 ? -7.658  107.331 63.874 1.00 114.13 ? 466 GLU A CB  1 
ATOM   3522  C CG  . GLU A 1 458 ? -7.329  108.105 62.594 1.00 131.64 ? 466 GLU A CG  1 
ATOM   3523  C CD  . GLU A 1 458 ? -8.469  108.819 61.885 1.00 125.15 ? 466 GLU A CD  1 
ATOM   3524  O OE1 . GLU A 1 458 ? -8.969  109.724 62.581 1.00 136.27 ? 466 GLU A OE1 1 
ATOM   3525  O OE2 . GLU A 1 458 ? -8.841  108.533 60.721 1.00 102.90 ? 466 GLU A OE2 1 
ATOM   3526  N N   . GLU A 1 459 ? -7.376  104.758 65.701 1.00 84.57  ? 467 GLU A N   1 
ATOM   3527  C CA  . GLU A 1 459 ? -6.626  103.916 66.634 1.00 95.52  ? 467 GLU A CA  1 
ATOM   3528  C C   . GLU A 1 459 ? -6.453  102.518 66.048 1.00 94.90  ? 467 GLU A C   1 
ATOM   3529  O O   . GLU A 1 459 ? -5.325  101.995 65.964 1.00 61.82  ? 467 GLU A O   1 
ATOM   3530  C CB  . GLU A 1 459 ? -7.256  103.833 68.028 1.00 79.41  ? 467 GLU A CB  1 
ATOM   3531  C CG  . GLU A 1 459 ? -6.378  104.508 69.080 1.00 78.25  ? 467 GLU A CG  1 
ATOM   3532  C CD  . GLU A 1 459 ? -6.769  104.137 70.511 1.00 125.27 ? 467 GLU A CD  1 
ATOM   3533  O OE1 . GLU A 1 459 ? -7.889  104.503 70.951 1.00 106.18 ? 467 GLU A OE1 1 
ATOM   3534  O OE2 . GLU A 1 459 ? -5.948  103.460 71.186 1.00 146.46 ? 467 GLU A OE2 1 
ATOM   3535  N N   . VAL A 1 460 ? -7.604  101.963 65.619 1.00 106.39 ? 468 VAL A N   1 
ATOM   3536  C CA  . VAL A 1 460 ? -7.696  100.613 65.090 1.00 88.90  ? 468 VAL A CA  1 
ATOM   3537  C C   . VAL A 1 460 ? -6.766  100.472 63.886 1.00 77.60  ? 468 VAL A C   1 
ATOM   3538  O O   . VAL A 1 460 ? -5.968  99.531  63.817 1.00 89.23  ? 468 VAL A O   1 
ATOM   3539  C CB  . VAL A 1 460 ? -9.152  100.291 64.713 1.00 84.36  ? 468 VAL A CB  1 
ATOM   3540  C CG1 . VAL A 1 460 ? -9.256  99.035  63.850 1.00 86.24  ? 468 VAL A CG1 1 
ATOM   3541  C CG2 . VAL A 1 460 ? -10.009 100.125 65.956 1.00 116.83 ? 468 VAL A CG2 1 
ATOM   3542  N N   . GLU A 1 461 ? -6.857  101.428 62.959 1.00 58.30  ? 469 GLU A N   1 
ATOM   3543  C CA  . GLU A 1 461 ? -6.018  101.403 61.769 1.00 84.23  ? 469 GLU A CA  1 
ATOM   3544  C C   . GLU A 1 461 ? -4.531  101.449 62.147 1.00 100.21 ? 469 GLU A C   1 
ATOM   3545  O O   . GLU A 1 461 ? -3.733  100.691 61.587 1.00 84.16  ? 469 GLU A O   1 
ATOM   3546  C CB  . GLU A 1 461 ? -6.407  102.461 60.729 1.00 77.49  ? 469 GLU A CB  1 
ATOM   3547  C CG  . GLU A 1 461 ? -7.799  102.295 60.149 1.00 60.22  ? 469 GLU A CG  1 
ATOM   3548  C CD  . GLU A 1 461 ? -8.160  103.253 59.044 1.00 81.83  ? 469 GLU A CD  1 
ATOM   3549  O OE1 . GLU A 1 461 ? -7.304  103.981 58.519 1.00 115.53 ? 469 GLU A OE1 1 
ATOM   3550  O OE2 . GLU A 1 461 ? -9.344  103.289 58.688 1.00 94.54  ? 469 GLU A OE2 1 
ATOM   3551  N N   . SER A 1 462 ? -4.145  102.347 63.069 1.00 104.33 ? 470 SER A N   1 
ATOM   3552  C CA  . SER A 1 462 ? -2.741  102.461 63.440 1.00 103.52 ? 470 SER A CA  1 
ATOM   3553  C C   . SER A 1 462 ? -2.223  101.138 64.014 1.00 101.46 ? 470 SER A C   1 
ATOM   3554  O O   . SER A 1 462 ? -1.128  100.725 63.650 1.00 108.93 ? 470 SER A O   1 
ATOM   3555  C CB  . SER A 1 462 ? -2.504  103.607 64.373 1.00 92.85  ? 470 SER A CB  1 
ATOM   3556  O OG  . SER A 1 462 ? -3.598  103.656 65.279 1.00 115.15 ? 470 SER A OG  1 
ATOM   3557  N N   . PHE A 1 463 ? -3.018  100.467 64.870 1.00 72.96  ? 471 PHE A N   1 
ATOM   3558  C CA  . PHE A 1 463 ? -2.639  99.180  65.438 1.00 76.56  ? 471 PHE A CA  1 
ATOM   3559  C C   . PHE A 1 463 ? -2.423  98.121  64.351 1.00 113.03 ? 471 PHE A C   1 
ATOM   3560  O O   . PHE A 1 463 ? -1.393  97.419  64.311 1.00 139.32 ? 471 PHE A O   1 
ATOM   3561  C CB  . PHE A 1 463 ? -3.724  98.661  66.377 1.00 60.46  ? 471 PHE A CB  1 
ATOM   3562  C CG  . PHE A 1 463 ? -3.432  97.297  66.987 1.00 80.16  ? 471 PHE A CG  1 
ATOM   3563  C CD1 . PHE A 1 463 ? -2.203  97.001  67.581 1.00 64.73  ? 471 PHE A CD1 1 
ATOM   3564  C CD2 . PHE A 1 463 ? -4.394  96.283  66.951 1.00 118.55 ? 471 PHE A CD2 1 
ATOM   3565  C CE1 . PHE A 1 463 ? -1.970  95.751  68.163 1.00 71.05  ? 471 PHE A CE1 1 
ATOM   3566  C CE2 . PHE A 1 463 ? -4.140  95.032  67.519 1.00 125.40 ? 471 PHE A CE2 1 
ATOM   3567  C CZ  . PHE A 1 463 ? -2.938  94.766  68.168 1.00 83.20  ? 471 PHE A CZ  1 
ATOM   3568  N N   . ALA A 1 464 ? -3.402  98.025  63.443 1.00 103.33 ? 472 ALA A N   1 
ATOM   3569  C CA  . ALA A 1 464 ? -3.346  97.058  62.355 1.00 89.22  ? 472 ALA A CA  1 
ATOM   3570  C C   . ALA A 1 464 ? -2.149  97.332  61.442 1.00 100.24 ? 472 ALA A C   1 
ATOM   3571  O O   . ALA A 1 464 ? -1.401  96.400  61.117 1.00 102.29 ? 472 ALA A O   1 
ATOM   3572  C CB  . ALA A 1 464 ? -4.626  97.140  61.581 1.00 98.84  ? 472 ALA A CB  1 
ATOM   3573  N N   . SER A 1 465 ? -1.919  98.627  61.133 1.00 93.84  ? 473 SER A N   1 
ATOM   3574  C CA  . SER A 1 465 ? -0.884  99.082  60.211 1.00 90.36  ? 473 SER A CA  1 
ATOM   3575  C C   . SER A 1 465 ? 0.473   98.571  60.664 1.00 95.81  ? 473 SER A C   1 
ATOM   3576  O O   . SER A 1 465 ? 1.399   98.537  59.876 1.00 110.34 ? 473 SER A O   1 
ATOM   3577  C CB  . SER A 1 465 ? -0.781  100.580 60.136 1.00 90.37  ? 473 SER A CB  1 
ATOM   3578  O OG  . SER A 1 465 ? -2.022  101.256 60.049 1.00 131.74 ? 473 SER A OG  1 
ATOM   3579  N N   . LEU A 1 466 ? 0.580   98.186  61.935 1.00 98.23  ? 474 LEU A N   1 
ATOM   3580  C CA  . LEU A 1 466 ? 1.856   97.758  62.465 1.00 94.09  ? 474 LEU A CA  1 
ATOM   3581  C C   . LEU A 1 466 ? 2.168   96.328  62.062 1.00 99.06  ? 474 LEU A C   1 
ATOM   3582  O O   . LEU A 1 466 ? 3.330   95.939  62.185 1.00 147.75 ? 474 LEU A O   1 
ATOM   3583  C CB  . LEU A 1 466 ? 1.851   97.871  63.986 1.00 84.25  ? 474 LEU A CB  1 
ATOM   3584  C CG  . LEU A 1 466 ? 1.612   99.265  64.548 1.00 73.40  ? 474 LEU A CG  1 
ATOM   3585  C CD1 . LEU A 1 466 ? 1.470   99.087  66.053 1.00 72.71  ? 474 LEU A CD1 1 
ATOM   3586  C CD2 . LEU A 1 466 ? 2.741   100.203 64.158 1.00 97.61  ? 474 LEU A CD2 1 
ATOM   3587  N N   . PHE A 1 467 ? 1.172   95.546  61.619 1.00 81.59  ? 475 PHE A N   1 
ATOM   3588  C CA  . PHE A 1 467 ? 1.495   94.185  61.215 1.00 89.38  ? 475 PHE A CA  1 
ATOM   3589  C C   . PHE A 1 467 ? 1.559   94.010  59.694 1.00 88.30  ? 475 PHE A C   1 
ATOM   3590  O O   . PHE A 1 467 ? 0.934   94.767  58.967 1.00 80.46  ? 475 PHE A O   1 
ATOM   3591  C CB  . PHE A 1 467 ? 0.495   93.185  61.764 1.00 96.64  ? 475 PHE A CB  1 
ATOM   3592  C CG  . PHE A 1 467 ? 0.297   93.272  63.264 1.00 106.44 ? 475 PHE A CG  1 
ATOM   3593  C CD1 . PHE A 1 467 ? -0.577  94.200  63.840 1.00 104.32 ? 475 PHE A CD1 1 
ATOM   3594  C CD2 . PHE A 1 467 ? 0.908   92.324  64.089 1.00 114.25 ? 475 PHE A CD2 1 
ATOM   3595  C CE1 . PHE A 1 467 ? -0.813  94.172  65.213 1.00 124.91 ? 475 PHE A CE1 1 
ATOM   3596  C CE2 . PHE A 1 467 ? 0.686   92.309  65.463 1.00 97.96  ? 475 PHE A CE2 1 
ATOM   3597  C CZ  . PHE A 1 467 ? -0.179  93.217  66.022 1.00 112.96 ? 475 PHE A CZ  1 
ATOM   3598  N N   . PRO A 1 468 ? 2.320   93.012  59.170 1.00 88.95  ? 476 PRO A N   1 
ATOM   3599  C CA  . PRO A 1 468 ? 2.523   92.889  57.717 1.00 80.49  ? 476 PRO A CA  1 
ATOM   3600  C C   . PRO A 1 468 ? 1.271   92.261  57.106 1.00 101.92 ? 476 PRO A C   1 
ATOM   3601  O O   . PRO A 1 468 ? 0.391   91.720  57.818 1.00 105.69 ? 476 PRO A O   1 
ATOM   3602  C CB  . PRO A 1 468 ? 3.757   91.980  57.603 1.00 66.40  ? 476 PRO A CB  1 
ATOM   3603  C CG  . PRO A 1 468 ? 3.652   91.089  58.864 1.00 65.62  ? 476 PRO A CG  1 
ATOM   3604  C CD  . PRO A 1 468 ? 2.977   91.932  59.945 1.00 65.57  ? 476 PRO A CD  1 
ATOM   3605  N N   . LEU A 1 469 ? 1.187   92.389  55.775 1.00 87.80  ? 477 LEU A N   1 
ATOM   3606  C CA  . LEU A 1 469 ? -0.021  91.995  55.053 1.00 91.26  ? 477 LEU A CA  1 
ATOM   3607  C C   . LEU A 1 469 ? 0.332   91.064  53.900 1.00 92.81  ? 477 LEU A C   1 
ATOM   3608  O O   . LEU A 1 469 ? 0.717   91.544  52.827 1.00 106.62 ? 477 LEU A O   1 
ATOM   3609  C CB  . LEU A 1 469 ? -0.717  93.235  54.506 1.00 94.78  ? 477 LEU A CB  1 
ATOM   3610  C CG  . LEU A 1 469 ? -1.982  92.973  53.692 1.00 94.73  ? 477 LEU A CG  1 
ATOM   3611  C CD1 . LEU A 1 469 ? -2.997  92.528  54.764 1.00 113.81 ? 477 LEU A CD1 1 
ATOM   3612  C CD2 . LEU A 1 469 ? -2.389  94.141  52.756 1.00 71.31  ? 477 LEU A CD2 1 
ATOM   3613  N N   . PRO A 1 470 ? 0.176   89.730  54.068 1.00 83.17  ? 478 PRO A N   1 
ATOM   3614  C CA  . PRO A 1 470 ? 0.848   88.765  53.196 1.00 78.91  ? 478 PRO A CA  1 
ATOM   3615  C C   . PRO A 1 470 ? 0.492   89.033  51.731 1.00 96.48  ? 478 PRO A C   1 
ATOM   3616  O O   . PRO A 1 470 ? -0.646  89.421  51.422 1.00 54.64  ? 478 PRO A O   1 
ATOM   3617  C CB  . PRO A 1 470 ? 0.357   87.396  53.692 1.00 80.09  ? 478 PRO A CB  1 
ATOM   3618  C CG  . PRO A 1 470 ? -0.160  87.637  55.084 1.00 86.69  ? 478 PRO A CG  1 
ATOM   3619  C CD  . PRO A 1 470 ? -0.615  89.111  55.140 1.00 104.24 ? 478 PRO A CD  1 
ATOM   3620  N N   . GLY A 1 471 ? 1.478   88.789  50.851 1.00 124.95 ? 479 GLY A N   1 
ATOM   3621  C CA  . GLY A 1 471 ? 1.254   88.877  49.421 1.00 130.77 ? 479 GLY A CA  1 
ATOM   3622  C C   . GLY A 1 471 ? 1.963   90.107  48.879 1.00 129.64 ? 479 GLY A C   1 
ATOM   3623  O O   . GLY A 1 471 ? 1.880   91.182  49.466 1.00 153.89 ? 479 GLY A O   1 
ATOM   3624  N N   . LEU A 1 472 ? 2.691   89.924  47.773 1.00 124.75 ? 480 LEU A N   1 
ATOM   3625  C CA  . LEU A 1 472 ? 3.566   90.941  47.202 1.00 128.87 ? 480 LEU A CA  1 
ATOM   3626  C C   . LEU A 1 472 ? 3.386   90.908  45.657 1.00 135.69 ? 480 LEU A C   1 
ATOM   3627  O O   . LEU A 1 472 ? 4.428   91.116  44.968 1.00 119.32 ? 480 LEU A O   1 
ATOM   3628  C CB  . LEU A 1 472 ? 5.051   90.923  47.638 1.00 79.58  ? 480 LEU A CB  1 
ATOM   3629  C CG  . LEU A 1 472 ? 5.457   91.664  48.939 1.00 84.08  ? 480 LEU A CG  1 
ATOM   3630  C CD1 . LEU A 1 472 ? 5.325   90.896  50.315 1.00 70.64  ? 480 LEU A CD1 1 
ATOM   3631  C CD2 . LEU A 1 472 ? 6.780   92.465  48.854 1.00 65.09  ? 480 LEU A CD2 1 
ATOM   3632  O OXT . LEU A 1 472 ? 2.210   90.665  45.182 1.00 87.49  ? 480 LEU A OXT 1 
ATOM   3633  N N   . GLN B 1 1   ? -81.111 51.257  68.082 1.00 82.81  ? 9   GLN B N   1 
ATOM   3634  C CA  . GLN B 1 1   ? -81.078 49.904  68.691 1.00 112.20 ? 9   GLN B CA  1 
ATOM   3635  C C   . GLN B 1 1   ? -82.215 49.799  69.700 1.00 141.91 ? 9   GLN B C   1 
ATOM   3636  O O   . GLN B 1 1   ? -83.096 48.953  69.490 1.00 142.70 ? 9   GLN B O   1 
ATOM   3637  C CB  . GLN B 1 1   ? -79.739 49.650  69.377 1.00 30.00  ? 9   GLN B CB  1 
ATOM   3638  C CG  . GLN B 1 1   ? -79.268 50.774  70.293 1.00 30.00  ? 9   GLN B CG  1 
ATOM   3639  C CD  . GLN B 1 1   ? -78.828 52.013  69.553 1.00 30.00  ? 9   GLN B CD  1 
ATOM   3640  O OE1 . GLN B 1 1   ? -79.588 52.967  69.397 1.00 30.00  ? 9   GLN B OE1 1 
ATOM   3641  N NE2 . GLN B 1 1   ? -77.590 52.008  69.087 1.00 30.00  ? 9   GLN B NE2 1 
ATOM   3642  N N   . GLY B 1 2   ? -82.189 50.618  70.754 1.00 132.69 ? 10  GLY B N   1 
ATOM   3643  C CA  . GLY B 1 2   ? -83.337 50.623  71.673 1.00 93.79  ? 10  GLY B CA  1 
ATOM   3644  C C   . GLY B 1 2   ? -84.587 50.613  70.825 1.00 110.08 ? 10  GLY B C   1 
ATOM   3645  O O   . GLY B 1 2   ? -85.490 49.814  71.114 1.00 164.50 ? 10  GLY B O   1 
ATOM   3646  N N   . ASP B 1 3   ? -84.617 51.447  69.785 1.00 116.21 ? 11  ASP B N   1 
ATOM   3647  C CA  . ASP B 1 3   ? -85.762 51.452  68.845 1.00 102.76 ? 11  ASP B CA  1 
ATOM   3648  C C   . ASP B 1 3   ? -85.603 50.241  67.937 1.00 111.55 ? 11  ASP B C   1 
ATOM   3649  O O   . ASP B 1 3   ? -85.231 50.422  66.783 1.00 101.04 ? 11  ASP B O   1 
ATOM   3650  C CB  . ASP B 1 3   ? -85.801 52.746  68.035 1.00 107.02 ? 11  ASP B CB  1 
ATOM   3651  C CG  . ASP B 1 3   ? -87.011 52.862  67.128 1.00 101.75 ? 11  ASP B CG  1 
ATOM   3652  O OD1 . ASP B 1 3   ? -87.784 51.889  67.054 1.00 99.92  ? 11  ASP B OD1 1 
ATOM   3653  O OD2 . ASP B 1 3   ? -87.168 53.925  66.501 1.00 103.76 ? 11  ASP B OD2 1 
ATOM   3654  N N   . ALA B 1 4   ? -85.823 49.045  68.470 1.00 92.19  ? 12  ALA B N   1 
ATOM   3655  C CA  . ALA B 1 4   ? -85.612 47.837  67.651 1.00 99.25  ? 12  ALA B CA  1 
ATOM   3656  C C   . ALA B 1 4   ? -86.353 48.020  66.332 1.00 110.87 ? 12  ALA B C   1 
ATOM   3657  O O   . ALA B 1 4   ? -85.823 47.621  65.287 1.00 118.38 ? 12  ALA B O   1 
ATOM   3658  C CB  . ALA B 1 4   ? -86.115 46.638  68.390 1.00 52.48  ? 12  ALA B CB  1 
ATOM   3659  N N   . ASP B 1 5   ? -87.543 48.605  66.393 1.00 87.04  ? 13  ASP B N   1 
ATOM   3660  C CA  . ASP B 1 5   ? -88.296 48.876  65.148 1.00 93.22  ? 13  ASP B CA  1 
ATOM   3661  C C   . ASP B 1 5   ? -87.328 49.511  64.162 1.00 100.56 ? 13  ASP B C   1 
ATOM   3662  O O   . ASP B 1 5   ? -87.382 49.169  62.974 1.00 65.60  ? 13  ASP B O   1 
ATOM   3663  C CB  . ASP B 1 5   ? -89.487 49.793  65.416 1.00 87.69  ? 13  ASP B CB  1 
ATOM   3664  C CG  . ASP B 1 5   ? -90.762 49.056  65.777 1.00 94.41  ? 13  ASP B CG  1 
ATOM   3665  O OD1 . ASP B 1 5   ? -90.788 47.821  65.620 1.00 91.98  ? 13  ASP B OD1 1 
ATOM   3666  O OD2 . ASP B 1 5   ? -91.717 49.726  66.207 1.00 86.10  ? 13  ASP B OD2 1 
ATOM   3667  N N   . LEU B 1 6   ? -86.463 50.396  64.654 1.00 114.85 ? 14  LEU B N   1 
ATOM   3668  C CA  . LEU B 1 6   ? -85.565 51.099  63.754 1.00 92.59  ? 14  LEU B CA  1 
ATOM   3669  C C   . LEU B 1 6   ? -84.517 50.114  63.254 1.00 92.35  ? 14  LEU B C   1 
ATOM   3670  O O   . LEU B 1 6   ? -84.259 50.016  62.061 1.00 62.38  ? 14  LEU B O   1 
ATOM   3671  C CB  . LEU B 1 6   ? -84.938 52.230  64.574 1.00 87.09  ? 14  LEU B CB  1 
ATOM   3672  C CG  . LEU B 1 6   ? -84.036 53.242  63.869 1.00 116.15 ? 14  LEU B CG  1 
ATOM   3673  C CD1 . LEU B 1 6   ? -84.544 53.762  62.518 1.00 95.79  ? 14  LEU B CD1 1 
ATOM   3674  C CD2 . LEU B 1 6   ? -83.895 54.388  64.870 1.00 126.18 ? 14  LEU B CD2 1 
ATOM   3675  N N   . TRP B 1 7   ? -83.992 49.288  64.173 1.00 117.43 ? 15  TRP B N   1 
ATOM   3676  C CA  . TRP B 1 7   ? -83.010 48.249  63.889 1.00 111.13 ? 15  TRP B CA  1 
ATOM   3677  C C   . TRP B 1 7   ? -83.494 47.278  62.804 1.00 94.33  ? 15  TRP B C   1 
ATOM   3678  O O   . TRP B 1 7   ? -82.725 46.852  61.937 1.00 101.94 ? 15  TRP B O   1 
ATOM   3679  C CB  . TRP B 1 7   ? -82.612 47.559  65.199 1.00 88.92  ? 15  TRP B CB  1 
ATOM   3680  C CG  . TRP B 1 7   ? -81.282 46.872  65.102 1.00 97.19  ? 15  TRP B CG  1 
ATOM   3681  C CD1 . TRP B 1 7   ? -81.009 45.597  65.480 1.00 108.79 ? 15  TRP B CD1 1 
ATOM   3682  C CD2 . TRP B 1 7   ? -80.054 47.405  64.552 1.00 100.28 ? 15  TRP B CD2 1 
ATOM   3683  N NE1 . TRP B 1 7   ? -79.694 45.298  65.229 1.00 101.59 ? 15  TRP B NE1 1 
ATOM   3684  C CE2 . TRP B 1 7   ? -79.088 46.387  64.653 1.00 99.41  ? 15  TRP B CE2 1 
ATOM   3685  C CE3 . TRP B 1 7   ? -79.688 48.630  63.978 1.00 109.40 ? 15  TRP B CE3 1 
ATOM   3686  C CZ2 . TRP B 1 7   ? -77.775 46.584  64.235 1.00 93.26  ? 15  TRP B CZ2 1 
ATOM   3687  C CZ3 . TRP B 1 7   ? -78.395 48.825  63.544 1.00 89.31  ? 15  TRP B CZ3 1 
ATOM   3688  C CH2 . TRP B 1 7   ? -77.452 47.813  63.698 1.00 109.58 ? 15  TRP B CH2 1 
ATOM   3689  N N   . SER B 1 8   ? -84.797 47.010  62.818 1.00 88.26  ? 16  SER B N   1 
ATOM   3690  C CA  . SER B 1 8   ? -85.419 46.161  61.831 1.00 112.64 ? 16  SER B CA  1 
ATOM   3691  C C   . SER B 1 8   ? -85.448 46.815  60.438 1.00 111.63 ? 16  SER B C   1 
ATOM   3692  O O   . SER B 1 8   ? -85.295 46.148  59.403 1.00 102.06 ? 16  SER B O   1 
ATOM   3693  C CB  . SER B 1 8   ? -86.773 45.767  62.333 1.00 99.35  ? 16  SER B CB  1 
ATOM   3694  O OG  . SER B 1 8   ? -87.318 44.821  61.438 1.00 163.93 ? 16  SER B OG  1 
ATOM   3695  N N   . SER B 1 9   ? -85.718 48.129  60.419 1.00 93.41  ? 17  SER B N   1 
ATOM   3696  C CA  . SER B 1 9   ? -85.778 48.872  59.170 1.00 121.03 ? 17  SER B CA  1 
ATOM   3697  C C   . SER B 1 9   ? -84.359 49.090  58.627 1.00 122.02 ? 17  SER B C   1 
ATOM   3698  O O   . SER B 1 9   ? -84.144 49.218  57.415 1.00 107.23 ? 17  SER B O   1 
ATOM   3699  C CB  . SER B 1 9   ? -86.455 50.197  59.367 1.00 94.34  ? 17  SER B CB  1 
ATOM   3700  O OG  . SER B 1 9   ? -85.387 51.122  59.511 1.00 77.57  ? 17  SER B OG  1 
ATOM   3701  N N   . HIS B 1 10  ? -83.368 49.122  59.528 1.00 100.72 ? 18  HIS B N   1 
ATOM   3702  C CA  . HIS B 1 10  ? -81.998 49.163  59.050 1.00 98.99  ? 18  HIS B CA  1 
ATOM   3703  C C   . HIS B 1 10  ? -81.677 47.898  58.231 1.00 87.21  ? 18  HIS B C   1 
ATOM   3704  O O   . HIS B 1 10  ? -81.121 48.007  57.127 1.00 88.33  ? 18  HIS B O   1 
ATOM   3705  C CB  . HIS B 1 10  ? -81.029 49.583  60.163 1.00 92.77  ? 18  HIS B CB  1 
ATOM   3706  C CG  . HIS B 1 10  ? -79.608 49.159  59.918 1.00 112.55 ? 18  HIS B CG  1 
ATOM   3707  N ND1 . HIS B 1 10  ? -79.167 47.885  60.214 1.00 127.96 ? 18  HIS B ND1 1 
ATOM   3708  C CD2 . HIS B 1 10  ? -78.536 49.816  59.432 1.00 119.82 ? 18  HIS B CD2 1 
ATOM   3709  C CE1 . HIS B 1 10  ? -77.876 47.783  59.892 1.00 141.05 ? 18  HIS B CE1 1 
ATOM   3710  N NE2 . HIS B 1 10  ? -77.475 48.939  59.409 1.00 132.38 ? 18  HIS B NE2 1 
ATOM   3711  N N   . ASP B 1 11  ? -81.998 46.706  58.768 1.00 73.42  ? 19  ASP B N   1 
ATOM   3712  C CA  . ASP B 1 11  ? -81.726 45.477  58.043 1.00 84.00  ? 19  ASP B CA  1 
ATOM   3713  C C   . ASP B 1 11  ? -82.452 45.596  56.704 1.00 123.73 ? 19  ASP B C   1 
ATOM   3714  O O   . ASP B 1 11  ? -81.982 45.071  55.679 1.00 138.06 ? 19  ASP B O   1 
ATOM   3715  C CB  . ASP B 1 11  ? -82.482 44.261  58.564 1.00 72.14  ? 19  ASP B CB  1 
ATOM   3716  C CG  . ASP B 1 11  ? -82.112 43.622  59.885 1.00 94.48  ? 19  ASP B CG  1 
ATOM   3717  O OD1 . ASP B 1 11  ? -80.971 43.098  59.969 1.00 112.19 ? 19  ASP B OD1 1 
ATOM   3718  O OD2 . ASP B 1 11  ? -83.027 43.558  60.745 1.00 78.11  ? 19  ASP B OD2 1 
ATOM   3719  N N   . ALA B 1 12  ? -83.625 46.264  56.759 1.00 98.95  ? 20  ALA B N   1 
ATOM   3720  C CA  . ALA B 1 12  ? -84.486 46.357  55.592 1.00 85.23  ? 20  ALA B CA  1 
ATOM   3721  C C   . ALA B 1 12  ? -83.779 47.156  54.495 1.00 90.30  ? 20  ALA B C   1 
ATOM   3722  O O   . ALA B 1 12  ? -83.799 46.785  53.330 1.00 77.59  ? 20  ALA B O   1 
ATOM   3723  C CB  . ALA B 1 12  ? -85.810 46.977  55.955 1.00 71.58  ? 20  ALA B CB  1 
ATOM   3724  N N   . MET B 1 13  ? -83.175 48.278  54.901 1.00 91.43  ? 21  MET B N   1 
ATOM   3725  C CA  . MET B 1 13  ? -82.549 49.210  53.977 1.00 83.26  ? 21  MET B CA  1 
ATOM   3726  C C   . MET B 1 13  ? -81.599 48.443  53.079 1.00 91.06  ? 21  MET B C   1 
ATOM   3727  O O   . MET B 1 13  ? -81.680 48.555  51.848 1.00 111.31 ? 21  MET B O   1 
ATOM   3728  C CB  . MET B 1 13  ? -81.669 50.204  54.724 1.00 75.25  ? 21  MET B CB  1 
ATOM   3729  C CG  . MET B 1 13  ? -81.415 51.417  53.860 1.00 95.84  ? 21  MET B CG  1 
ATOM   3730  S SD  . MET B 1 13  ? -80.640 52.824  54.697 1.00 113.22 ? 21  MET B SD  1 
ATOM   3731  C CE  . MET B 1 13  ? -81.208 52.763  56.403 1.00 78.28  ? 21  MET B CE  1 
ATOM   3732  N N   . LEU B 1 14  ? -80.724 47.665  53.738 1.00 88.79  ? 22  LEU B N   1 
ATOM   3733  C CA  . LEU B 1 14  ? -79.686 46.880  53.068 1.00 77.76  ? 22  LEU B CA  1 
ATOM   3734  C C   . LEU B 1 14  ? -80.299 45.893  52.086 1.00 97.88  ? 22  LEU B C   1 
ATOM   3735  O O   . LEU B 1 14  ? -79.623 45.396  51.201 1.00 108.32 ? 22  LEU B O   1 
ATOM   3736  C CB  . LEU B 1 14  ? -78.759 46.112  54.005 1.00 60.66  ? 22  LEU B CB  1 
ATOM   3737  C CG  . LEU B 1 14  ? -78.141 46.949  55.128 1.00 82.62  ? 22  LEU B CG  1 
ATOM   3738  C CD1 . LEU B 1 14  ? -77.274 46.083  56.054 1.00 48.76  ? 22  LEU B CD1 1 
ATOM   3739  C CD2 . LEU B 1 14  ? -77.397 48.177  54.544 1.00 77.32  ? 22  LEU B CD2 1 
ATOM   3740  N N   . ALA B 1 15  ? -81.598 45.631  52.247 1.00 102.20 ? 23  ALA B N   1 
ATOM   3741  C CA  . ALA B 1 15  ? -82.258 44.564  51.536 1.00 100.02 ? 23  ALA B CA  1 
ATOM   3742  C C   . ALA B 1 15  ? -83.243 45.086  50.480 1.00 101.06 ? 23  ALA B C   1 
ATOM   3743  O O   . ALA B 1 15  ? -83.716 44.284  49.670 1.00 95.56  ? 23  ALA B O   1 
ATOM   3744  C CB  . ALA B 1 15  ? -82.909 43.708  52.570 1.00 84.65  ? 23  ALA B CB  1 
ATOM   3745  N N   . GLN B 1 16  ? -83.540 46.392  50.467 1.00 103.96 ? 24  GLN B N   1 
ATOM   3746  C CA  . GLN B 1 16  ? -84.612 46.894  49.620 1.00 113.07 ? 24  GLN B CA  1 
ATOM   3747  C C   . GLN B 1 16  ? -84.197 46.913  48.152 1.00 104.98 ? 24  GLN B C   1 
ATOM   3748  O O   . GLN B 1 16  ? -83.052 47.257  47.842 1.00 106.06 ? 24  GLN B O   1 
ATOM   3749  C CB  . GLN B 1 16  ? -85.074 48.252  50.135 1.00 115.79 ? 24  GLN B CB  1 
ATOM   3750  C CG  . GLN B 1 16  ? -86.542 48.497  49.820 1.00 118.84 ? 24  GLN B CG  1 
ATOM   3751  C CD  . GLN B 1 16  ? -87.000 49.843  50.305 1.00 132.84 ? 24  GLN B CD  1 
ATOM   3752  O OE1 . GLN B 1 16  ? -86.516 50.305  51.340 1.00 201.87 ? 24  GLN B OE1 1 
ATOM   3753  N NE2 . GLN B 1 16  ? -87.933 50.482  49.616 1.00 152.03 ? 24  GLN B NE2 1 
ATOM   3754  N N   . PRO B 1 17  ? -85.102 46.545  47.201 1.00 107.70 ? 25  PRO B N   1 
ATOM   3755  C CA  . PRO B 1 17  ? -84.883 46.732  45.758 1.00 100.03 ? 25  PRO B CA  1 
ATOM   3756  C C   . PRO B 1 17  ? -84.519 48.153  45.393 1.00 85.67  ? 25  PRO B C   1 
ATOM   3757  O O   . PRO B 1 17  ? -84.945 49.091  46.091 1.00 55.47  ? 25  PRO B O   1 
ATOM   3758  C CB  . PRO B 1 17  ? -86.212 46.388  45.066 1.00 89.03  ? 25  PRO B CB  1 
ATOM   3759  C CG  . PRO B 1 17  ? -86.862 45.462  46.066 1.00 121.20 ? 25  PRO B CG  1 
ATOM   3760  C CD  . PRO B 1 17  ? -86.417 45.941  47.454 1.00 121.81 ? 25  PRO B CD  1 
ATOM   3761  N N   . LEU B 1 18  ? -83.789 48.261  44.275 1.00 93.22  ? 26  LEU B N   1 
ATOM   3762  C CA  . LEU B 1 18  ? -83.366 49.564  43.784 1.00 103.62 ? 26  LEU B CA  1 
ATOM   3763  C C   . LEU B 1 18  ? -84.600 50.388  43.456 1.00 113.60 ? 26  LEU B C   1 
ATOM   3764  O O   . LEU B 1 18  ? -84.705 51.579  43.819 1.00 90.95  ? 26  LEU B O   1 
ATOM   3765  C CB  . LEU B 1 18  ? -82.469 49.553  42.552 1.00 78.05  ? 26  LEU B CB  1 
ATOM   3766  C CG  . LEU B 1 18  ? -81.961 50.961  42.232 1.00 68.94  ? 26  LEU B CG  1 
ATOM   3767  C CD1 . LEU B 1 18  ? -81.094 51.451  43.395 1.00 77.87  ? 26  LEU B CD1 1 
ATOM   3768  C CD2 . LEU B 1 18  ? -81.365 51.260  40.878 1.00 50.90  ? 26  LEU B CD2 1 
ATOM   3769  N N   . LYS B 1 19  ? -85.500 49.685  42.743 1.00 115.15 ? 27  LYS B N   1 
ATOM   3770  C CA  . LYS B 1 19  ? -86.739 50.251  42.241 1.00 123.52 ? 27  LYS B CA  1 
ATOM   3771  C C   . LYS B 1 19  ? -87.418 51.055  43.348 1.00 112.03 ? 27  LYS B C   1 
ATOM   3772  O O   . LYS B 1 19  ? -87.935 52.139  43.039 1.00 79.26  ? 27  LYS B O   1 
ATOM   3773  C CB  . LYS B 1 19  ? -87.561 49.160  41.542 1.00 126.12 ? 27  LYS B CB  1 
ATOM   3774  C CG  . LYS B 1 19  ? -88.929 49.507  40.951 1.00 127.08 ? 27  LYS B CG  1 
ATOM   3775  C CD  . LYS B 1 19  ? -89.534 48.549  39.910 1.00 124.40 ? 27  LYS B CD  1 
ATOM   3776  C CE  . LYS B 1 19  ? -89.605 47.082  40.219 1.00 110.27 ? 27  LYS B CE  1 
ATOM   3777  N NZ  . LYS B 1 19  ? -89.977 46.905  41.634 1.00 138.87 ? 27  LYS B NZ  1 
ATOM   3778  N N   . ASP B 1 20  ? -87.328 50.579  44.609 1.00 98.80  ? 28  ASP B N   1 
ATOM   3779  C CA  . ASP B 1 20  ? -88.093 51.199  45.688 1.00 78.56  ? 28  ASP B CA  1 
ATOM   3780  C C   . ASP B 1 20  ? -87.207 52.115  46.508 1.00 85.72  ? 28  ASP B C   1 
ATOM   3781  O O   . ASP B 1 20  ? -87.628 53.217  46.882 1.00 142.71 ? 28  ASP B O   1 
ATOM   3782  C CB  . ASP B 1 20  ? -88.866 50.250  46.592 1.00 56.62  ? 28  ASP B CB  1 
ATOM   3783  C CG  . ASP B 1 20  ? -89.587 49.084  45.916 1.00 89.69  ? 28  ASP B CG  1 
ATOM   3784  O OD1 . ASP B 1 20  ? -89.939 49.152  44.708 1.00 95.93  ? 28  ASP B OD1 1 
ATOM   3785  O OD2 . ASP B 1 20  ? -89.785 48.050  46.595 1.00 116.59 ? 28  ASP B OD2 1 
ATOM   3786  N N   . SER B 1 21  ? -85.986 51.658  46.782 1.00 96.29  ? 29  SER B N   1 
ATOM   3787  C CA  . SER B 1 21  ? -85.044 52.478  47.530 1.00 117.79 ? 29  SER B CA  1 
ATOM   3788  C C   . SER B 1 21  ? -84.251 53.316  46.533 1.00 140.52 ? 29  SER B C   1 
ATOM   3789  O O   . SER B 1 21  ? -83.482 52.779  45.741 1.00 187.26 ? 29  SER B O   1 
ATOM   3790  C CB  . SER B 1 21  ? -84.165 51.613  48.391 1.00 127.54 ? 29  SER B CB  1 
ATOM   3791  O OG  . SER B 1 21  ? -83.146 52.402  48.983 1.00 154.52 ? 29  SER B OG  1 
ATOM   3792  N N   . ASP B 1 22  ? -84.561 54.618  46.488 1.00 123.00 ? 30  ASP B N   1 
ATOM   3793  C CA  . ASP B 1 22  ? -83.919 55.521  45.552 1.00 140.03 ? 30  ASP B CA  1 
ATOM   3794  C C   . ASP B 1 22  ? -84.439 55.249  44.146 1.00 131.63 ? 30  ASP B C   1 
ATOM   3795  O O   . ASP B 1 22  ? -83.735 54.702  43.260 1.00 75.78  ? 30  ASP B O   1 
ATOM   3796  C CB  . ASP B 1 22  ? -82.411 55.512  45.665 1.00 133.97 ? 30  ASP B CB  1 
ATOM   3797  C CG  . ASP B 1 22  ? -81.705 56.596  44.876 1.00 123.08 ? 30  ASP B CG  1 
ATOM   3798  O OD1 . ASP B 1 22  ? -82.313 57.205  43.938 1.00 138.43 ? 30  ASP B OD1 1 
ATOM   3799  O OD2 . ASP B 1 22  ? -80.551 56.825  45.240 1.00 110.49 ? 30  ASP B OD2 1 
ATOM   3800  N N   . VAL B 1 23  ? -85.661 55.746  43.959 1.00 113.28 ? 31  VAL B N   1 
ATOM   3801  C CA  . VAL B 1 23  ? -86.268 55.678  42.653 1.00 104.45 ? 31  VAL B CA  1 
ATOM   3802  C C   . VAL B 1 23  ? -85.589 56.626  41.669 1.00 106.81 ? 31  VAL B C   1 
ATOM   3803  O O   . VAL B 1 23  ? -85.543 56.312  40.482 1.00 94.88  ? 31  VAL B O   1 
ATOM   3804  C CB  . VAL B 1 23  ? -87.773 55.904  42.662 1.00 90.53  ? 31  VAL B CB  1 
ATOM   3805  C CG1 . VAL B 1 23  ? -88.308 55.287  41.367 1.00 94.72  ? 31  VAL B CG1 1 
ATOM   3806  C CG2 . VAL B 1 23  ? -88.404 55.378  43.960 1.00 88.79  ? 31  VAL B CG2 1 
ATOM   3807  N N   . GLU B 1 24  ? -85.062 57.759  42.170 1.00 100.13 ? 32  GLU B N   1 
ATOM   3808  C CA  . GLU B 1 24  ? -84.417 58.732  41.288 1.00 91.80  ? 32  GLU B CA  1 
ATOM   3809  C C   . GLU B 1 24  ? -83.358 58.025  40.434 1.00 96.40  ? 32  GLU B C   1 
ATOM   3810  O O   . GLU B 1 24  ? -83.364 58.128  39.198 1.00 90.94  ? 32  GLU B O   1 
ATOM   3811  C CB  . GLU B 1 24  ? -83.709 59.899  41.972 1.00 81.19  ? 32  GLU B CB  1 
ATOM   3812  C CG  . GLU B 1 24  ? -84.389 60.460  43.217 1.00 95.75  ? 32  GLU B CG  1 
ATOM   3813  C CD  . GLU B 1 24  ? -83.906 61.912  43.305 1.00 104.97 ? 32  GLU B CD  1 
ATOM   3814  O OE1 . GLU B 1 24  ? -83.466 62.371  44.400 1.00 100.27 ? 32  GLU B OE1 1 
ATOM   3815  O OE2 . GLU B 1 24  ? -83.926 62.577  42.227 1.00 81.86  ? 32  GLU B OE2 1 
ATOM   3816  N N   . VAL B 1 25  ? -82.532 57.207  41.102 1.00 73.80  ? 33  VAL B N   1 
ATOM   3817  C CA  . VAL B 1 25  ? -81.462 56.539  40.402 1.00 85.68  ? 33  VAL B CA  1 
ATOM   3818  C C   . VAL B 1 25  ? -82.034 55.479  39.463 1.00 101.29 ? 33  VAL B C   1 
ATOM   3819  O O   . VAL B 1 25  ? -81.647 55.412  38.283 1.00 108.59 ? 33  VAL B O   1 
ATOM   3820  C CB  . VAL B 1 25  ? -80.412 55.962  41.357 1.00 81.69  ? 33  VAL B CB  1 
ATOM   3821  C CG1 . VAL B 1 25  ? -79.455 55.060  40.566 1.00 72.13  ? 33  VAL B CG1 1 
ATOM   3822  C CG2 . VAL B 1 25  ? -79.674 57.084  42.097 1.00 58.93  ? 33  VAL B CG2 1 
ATOM   3823  N N   . TYR B 1 26  ? -82.931 54.636  40.017 1.00 77.17  ? 34  TYR B N   1 
ATOM   3824  C CA  . TYR B 1 26  ? -83.624 53.626  39.231 1.00 85.63  ? 34  TYR B CA  1 
ATOM   3825  C C   . TYR B 1 26  ? -84.062 54.240  37.890 1.00 96.67  ? 34  TYR B C   1 
ATOM   3826  O O   . TYR B 1 26  ? -83.840 53.658  36.795 1.00 68.99  ? 34  TYR B O   1 
ATOM   3827  C CB  . TYR B 1 26  ? -84.796 53.008  40.005 1.00 79.47  ? 34  TYR B CB  1 
ATOM   3828  C CG  . TYR B 1 26  ? -85.579 51.969  39.206 1.00 82.23  ? 34  TYR B CG  1 
ATOM   3829  C CD1 . TYR B 1 26  ? -85.197 50.633  39.194 1.00 89.44  ? 34  TYR B CD1 1 
ATOM   3830  C CD2 . TYR B 1 26  ? -86.643 52.334  38.388 1.00 80.87  ? 34  TYR B CD2 1 
ATOM   3831  C CE1 . TYR B 1 26  ? -85.879 49.683  38.454 1.00 95.65  ? 34  TYR B CE1 1 
ATOM   3832  C CE2 . TYR B 1 26  ? -87.284 51.411  37.575 1.00 83.95  ? 34  TYR B CE2 1 
ATOM   3833  C CZ  . TYR B 1 26  ? -86.922 50.080  37.632 1.00 93.85  ? 34  TYR B CZ  1 
ATOM   3834  O OH  . TYR B 1 26  ? -87.648 49.217  36.861 1.00 84.17  ? 34  TYR B OH  1 
ATOM   3835  N N   . ASN B 1 27  ? -84.664 55.445  37.976 1.00 79.87  ? 35  ASN B N   1 
ATOM   3836  C CA  . ASN B 1 27  ? -85.227 56.021  36.760 1.00 93.05  ? 35  ASN B CA  1 
ATOM   3837  C C   . ASN B 1 27  ? -84.101 56.385  35.814 1.00 91.29  ? 35  ASN B C   1 
ATOM   3838  O O   . ASN B 1 27  ? -84.193 56.094  34.622 1.00 60.48  ? 35  ASN B O   1 
ATOM   3839  C CB  . ASN B 1 27  ? -86.050 57.293  36.916 1.00 78.75  ? 35  ASN B CB  1 
ATOM   3840  C CG  . ASN B 1 27  ? -87.215 57.143  37.856 1.00 90.98  ? 35  ASN B CG  1 
ATOM   3841  O OD1 . ASN B 1 27  ? -87.835 56.072  37.993 1.00 98.54  ? 35  ASN B OD1 1 
ATOM   3842  N ND2 . ASN B 1 27  ? -87.490 58.232  38.554 1.00 107.27 ? 35  ASN B ND2 1 
ATOM   3843  N N   . ILE B 1 28  ? -83.058 57.021  36.364 1.00 99.32  ? 36  ILE B N   1 
ATOM   3844  C CA  . ILE B 1 28  ? -81.925 57.429  35.554 1.00 119.84 ? 36  ILE B CA  1 
ATOM   3845  C C   . ILE B 1 28  ? -81.434 56.214  34.771 1.00 112.78 ? 36  ILE B C   1 
ATOM   3846  O O   . ILE B 1 28  ? -81.315 56.268  33.549 1.00 88.01  ? 36  ILE B O   1 
ATOM   3847  C CB  . ILE B 1 28  ? -80.823 58.042  36.429 1.00 134.09 ? 36  ILE B CB  1 
ATOM   3848  C CG1 . ILE B 1 28  ? -81.331 59.328  37.113 1.00 117.99 ? 36  ILE B CG1 1 
ATOM   3849  C CG2 . ILE B 1 28  ? -79.565 58.274  35.579 1.00 119.75 ? 36  ILE B CG2 1 
ATOM   3850  C CD1 . ILE B 1 28  ? -80.222 60.243  37.603 1.00 140.80 ? 36  ILE B CD1 1 
ATOM   3851  N N   . ILE B 1 29  ? -81.184 55.112  35.484 1.00 99.66  ? 37  ILE B N   1 
ATOM   3852  C CA  . ILE B 1 29  ? -80.742 53.900  34.810 1.00 101.42 ? 37  ILE B CA  1 
ATOM   3853  C C   . ILE B 1 29  ? -81.730 53.477  33.716 1.00 105.83 ? 37  ILE B C   1 
ATOM   3854  O O   . ILE B 1 29  ? -81.298 53.187  32.585 1.00 82.20  ? 37  ILE B O   1 
ATOM   3855  C CB  . ILE B 1 29  ? -80.444 52.759  35.786 1.00 87.20  ? 37  ILE B CB  1 
ATOM   3856  C CG1 . ILE B 1 29  ? -79.491 53.226  36.878 1.00 109.80 ? 37  ILE B CG1 1 
ATOM   3857  C CG2 . ILE B 1 29  ? -79.857 51.581  34.999 1.00 80.93  ? 37  ILE B CG2 1 
ATOM   3858  C CD1 . ILE B 1 29  ? -79.207 52.187  37.943 1.00 134.99 ? 37  ILE B CD1 1 
ATOM   3859  N N   . LYS B 1 30  ? -83.035 53.428  34.056 1.00 82.04  ? 38  LYS B N   1 
ATOM   3860  C CA  . LYS B 1 30  ? -84.066 53.063  33.074 1.00 72.23  ? 38  LYS B CA  1 
ATOM   3861  C C   . LYS B 1 30  ? -84.057 54.048  31.895 1.00 68.05  ? 38  LYS B C   1 
ATOM   3862  O O   . LYS B 1 30  ? -84.035 53.640  30.730 1.00 64.21  ? 38  LYS B O   1 
ATOM   3863  C CB  . LYS B 1 30  ? -85.505 52.911  33.602 1.00 68.77  ? 38  LYS B CB  1 
ATOM   3864  C CG  . LYS B 1 30  ? -86.623 52.939  32.465 1.00 76.75  ? 38  LYS B CG  1 
ATOM   3865  C CD  . LYS B 1 30  ? -88.173 52.879  32.503 1.00 85.91  ? 38  LYS B CD  1 
ATOM   3866  C CE  . LYS B 1 30  ? -89.067 53.728  33.451 1.00 86.50  ? 38  LYS B CE  1 
ATOM   3867  N NZ  . LYS B 1 30  ? -89.232 55.195  33.338 1.00 59.63  ? 38  LYS B NZ  1 
ATOM   3868  N N   . LYS B 1 31  ? -84.072 55.355  32.198 1.00 53.60  ? 39  LYS B N   1 
ATOM   3869  C CA  . LYS B 1 31  ? -84.044 56.381  31.167 1.00 67.21  ? 39  LYS B CA  1 
ATOM   3870  C C   . LYS B 1 31  ? -82.825 56.178  30.256 1.00 83.28  ? 39  LYS B C   1 
ATOM   3871  O O   . LYS B 1 31  ? -82.898 56.433  29.063 1.00 123.38 ? 39  LYS B O   1 
ATOM   3872  C CB  . LYS B 1 31  ? -84.037 57.806  31.735 1.00 68.65  ? 39  LYS B CB  1 
ATOM   3873  C CG  . LYS B 1 31  ? -85.306 58.332  32.384 1.00 58.90  ? 39  LYS B CG  1 
ATOM   3874  C CD  . LYS B 1 31  ? -85.138 59.719  33.008 1.00 68.60  ? 39  LYS B CD  1 
ATOM   3875  C CE  . LYS B 1 31  ? -85.835 59.767  34.368 1.00 77.75  ? 39  LYS B CE  1 
ATOM   3876  N NZ  . LYS B 1 31  ? -85.520 60.811  35.368 1.00 73.22  ? 39  LYS B NZ  1 
ATOM   3877  N N   . GLU B 1 32  ? -81.671 55.829  30.836 1.00 90.89  ? 40  GLU B N   1 
ATOM   3878  C CA  . GLU B 1 32  ? -80.439 55.681  30.082 1.00 95.54  ? 40  GLU B CA  1 
ATOM   3879  C C   . GLU B 1 32  ? -80.547 54.455  29.176 1.00 105.23 ? 40  GLU B C   1 
ATOM   3880  O O   . GLU B 1 32  ? -80.131 54.477  28.008 1.00 74.43  ? 40  GLU B O   1 
ATOM   3881  C CB  . GLU B 1 32  ? -79.234 55.559  31.016 1.00 71.35  ? 40  GLU B CB  1 
ATOM   3882  C CG  . GLU B 1 32  ? -77.937 55.258  30.269 1.00 66.76  ? 40  GLU B CG  1 
ATOM   3883  C CD  . GLU B 1 32  ? -77.553 56.347  29.262 1.00 84.19  ? 40  GLU B CD  1 
ATOM   3884  O OE1 . GLU B 1 32  ? -78.108 57.494  29.172 1.00 97.39  ? 40  GLU B OE1 1 
ATOM   3885  O OE2 . GLU B 1 32  ? -76.631 55.999  28.515 1.00 66.43  ? 40  GLU B OE2 1 
ATOM   3886  N N   . SER B 1 33  ? -81.108 53.383  29.759 1.00 86.77  ? 41  SER B N   1 
ATOM   3887  C CA  . SER B 1 33  ? -81.294 52.145  29.030 1.00 76.68  ? 41  SER B CA  1 
ATOM   3888  C C   . SER B 1 33  ? -82.136 52.389  27.783 1.00 93.89  ? 41  SER B C   1 
ATOM   3889  O O   . SER B 1 33  ? -81.851 51.826  26.700 1.00 73.71  ? 41  SER B O   1 
ATOM   3890  C CB  . SER B 1 33  ? -81.925 51.113  29.896 1.00 58.38  ? 41  SER B CB  1 
ATOM   3891  O OG  . SER B 1 33  ? -82.732 50.225  29.127 1.00 77.58  ? 41  SER B OG  1 
ATOM   3892  N N   . ASN B 1 34  ? -83.180 53.219  27.974 1.00 83.12  ? 42  ASN B N   1 
ATOM   3893  C CA  . ASN B 1 34  ? -84.082 53.486  26.870 1.00 111.64 ? 42  ASN B CA  1 
ATOM   3894  C C   . ASN B 1 34  ? -83.342 54.313  25.814 1.00 106.48 ? 42  ASN B C   1 
ATOM   3895  O O   . ASN B 1 34  ? -83.453 54.052  24.600 1.00 92.62  ? 42  ASN B O   1 
ATOM   3896  C CB  . ASN B 1 34  ? -85.411 54.062  27.341 1.00 93.68  ? 42  ASN B CB  1 
ATOM   3897  C CG  . ASN B 1 34  ? -86.274 54.315  26.139 1.00 104.57 ? 42  ASN B CG  1 
ATOM   3898  O OD1 . ASN B 1 34  ? -86.722 53.354  25.511 1.00 121.88 ? 42  ASN B OD1 1 
ATOM   3899  N ND2 . ASN B 1 34  ? -86.507 55.572  25.789 1.00 121.29 ? 42  ASN B ND2 1 
ATOM   3900  N N   . ARG B 1 35  ? -82.568 55.291  26.316 1.00 76.38  ? 43  ARG B N   1 
ATOM   3901  C CA  . ARG B 1 35  ? -81.804 56.165  25.439 1.00 90.46  ? 43  ARG B CA  1 
ATOM   3902  C C   . ARG B 1 35  ? -80.887 55.310  24.551 1.00 88.08  ? 43  ARG B C   1 
ATOM   3903  O O   . ARG B 1 35  ? -80.779 55.579  23.343 1.00 71.82  ? 43  ARG B O   1 
ATOM   3904  C CB  . ARG B 1 35  ? -81.073 57.280  26.205 1.00 78.82  ? 43  ARG B CB  1 
ATOM   3905  C CG  . ARG B 1 35  ? -80.046 57.921  25.270 1.00 78.21  ? 43  ARG B CG  1 
ATOM   3906  C CD  . ARG B 1 35  ? -78.897 58.469  26.124 1.00 81.89  ? 43  ARG B CD  1 
ATOM   3907  N NE  . ARG B 1 35  ? -77.650 58.496  25.353 1.00 87.07  ? 43  ARG B NE  1 
ATOM   3908  C CZ  . ARG B 1 35  ? -76.666 57.593  25.421 1.00 107.14 ? 43  ARG B CZ  1 
ATOM   3909  N NH1 . ARG B 1 35  ? -76.936 56.432  26.005 1.00 104.17 ? 43  ARG B NH1 1 
ATOM   3910  N NH2 . ARG B 1 35  ? -75.446 57.816  24.931 1.00 143.90 ? 43  ARG B NH2 1 
ATOM   3911  N N   . GLN B 1 36  ? -80.226 54.309  25.175 1.00 65.50  ? 44  GLN B N   1 
ATOM   3912  C CA  . GLN B 1 36  ? -79.263 53.446  24.500 1.00 78.13  ? 44  GLN B CA  1 
ATOM   3913  C C   . GLN B 1 36  ? -79.992 52.686  23.406 1.00 89.61  ? 44  GLN B C   1 
ATOM   3914  O O   . GLN B 1 36  ? -79.521 52.683  22.251 1.00 68.03  ? 44  GLN B O   1 
ATOM   3915  C CB  . GLN B 1 36  ? -78.417 52.529  25.394 1.00 78.99  ? 44  GLN B CB  1 
ATOM   3916  C CG  . GLN B 1 36  ? -77.301 53.272  26.137 1.00 96.79  ? 44  GLN B CG  1 
ATOM   3917  C CD  . GLN B 1 36  ? -76.620 52.492  27.245 1.00 103.44 ? 44  GLN B CD  1 
ATOM   3918  O OE1 . GLN B 1 36  ? -76.289 51.308  27.099 1.00 99.35  ? 44  GLN B OE1 1 
ATOM   3919  N NE2 . GLN B 1 36  ? -76.412 53.138  28.389 1.00 95.95  ? 44  GLN B NE2 1 
ATOM   3920  N N   . ARG B 1 37  ? -81.232 52.265  23.732 1.00 87.28  ? 45  ARG B N   1 
ATOM   3921  C CA  . ARG B 1 37  ? -82.013 51.374  22.871 1.00 94.18  ? 45  ARG B CA  1 
ATOM   3922  C C   . ARG B 1 37  ? -82.413 52.059  21.559 1.00 104.13 ? 45  ARG B C   1 
ATOM   3923  O O   . ARG B 1 37  ? -82.268 51.481  20.474 1.00 105.80 ? 45  ARG B O   1 
ATOM   3924  C CB  . ARG B 1 37  ? -83.265 50.910  23.614 1.00 103.28 ? 45  ARG B CB  1 
ATOM   3925  C CG  . ARG B 1 37  ? -83.940 49.638  23.131 1.00 102.77 ? 45  ARG B CG  1 
ATOM   3926  C CD  . ARG B 1 37  ? -85.235 49.332  23.904 1.00 92.93  ? 45  ARG B CD  1 
ATOM   3927  N NE  . ARG B 1 37  ? -86.223 50.404  23.714 1.00 107.45 ? 45  ARG B NE  1 
ATOM   3928  C CZ  . ARG B 1 37  ? -86.780 50.808  22.538 1.00 122.49 ? 45  ARG B CZ  1 
ATOM   3929  N NH1 . ARG B 1 37  ? -87.506 51.926  22.495 1.00 89.43  ? 45  ARG B NH1 1 
ATOM   3930  N NH2 . ARG B 1 37  ? -86.587 50.132  21.404 1.00 96.90  ? 45  ARG B NH2 1 
ATOM   3931  N N   . VAL B 1 38  ? -82.832 53.333  21.652 1.00 93.94  ? 46  VAL B N   1 
ATOM   3932  C CA  . VAL B 1 38  ? -83.358 54.035  20.494 1.00 85.86  ? 46  VAL B CA  1 
ATOM   3933  C C   . VAL B 1 38  ? -82.279 54.731  19.663 1.00 92.64  ? 46  VAL B C   1 
ATOM   3934  O O   . VAL B 1 38  ? -82.586 55.205  18.563 1.00 92.65  ? 46  VAL B O   1 
ATOM   3935  C CB  . VAL B 1 38  ? -84.401 55.067  20.936 1.00 82.65  ? 46  VAL B CB  1 
ATOM   3936  C CG1 . VAL B 1 38  ? -85.475 54.410  21.818 1.00 71.20  ? 46  VAL B CG1 1 
ATOM   3937  C CG2 . VAL B 1 38  ? -83.703 56.253  21.608 1.00 83.13  ? 46  VAL B CG2 1 
ATOM   3938  N N   . GLY B 1 39  ? -81.046 54.838  20.183 1.00 90.46  ? 47  GLY B N   1 
ATOM   3939  C CA  . GLY B 1 39  ? -80.009 55.598  19.492 1.00 101.72 ? 47  GLY B CA  1 
ATOM   3940  C C   . GLY B 1 39  ? -79.133 54.699  18.616 1.00 131.58 ? 47  GLY B C   1 
ATOM   3941  O O   . GLY B 1 39  ? -79.022 53.484  18.827 1.00 150.85 ? 47  GLY B O   1 
ATOM   3942  N N   . LEU B 1 40  ? -78.502 55.315  17.615 1.00 140.73 ? 48  LEU B N   1 
ATOM   3943  C CA  . LEU B 1 40  ? -77.488 54.637  16.823 1.00 143.35 ? 48  LEU B CA  1 
ATOM   3944  C C   . LEU B 1 40  ? -76.116 55.030  17.373 1.00 133.61 ? 48  LEU B C   1 
ATOM   3945  O O   . LEU B 1 40  ? -75.615 56.134  17.083 1.00 95.13  ? 48  LEU B O   1 
ATOM   3946  C CB  . LEU B 1 40  ? -77.622 55.047  15.360 1.00 144.67 ? 48  LEU B CB  1 
ATOM   3947  C CG  . LEU B 1 40  ? -78.815 54.469  14.596 1.00 137.28 ? 48  LEU B CG  1 
ATOM   3948  C CD1 . LEU B 1 40  ? -78.698 54.841  13.144 1.00 134.01 ? 48  LEU B CD1 1 
ATOM   3949  C CD2 . LEU B 1 40  ? -78.879 52.975  14.664 1.00 152.40 ? 48  LEU B CD2 1 
ATOM   3950  N N   . GLU B 1 41  ? -75.501 54.101  18.135 1.00 119.97 ? 49  GLU B N   1 
ATOM   3951  C CA  . GLU B 1 41  ? -74.197 54.384  18.708 1.00 103.67 ? 49  GLU B CA  1 
ATOM   3952  C C   . GLU B 1 41  ? -73.045 54.062  17.751 1.00 98.88  ? 49  GLU B C   1 
ATOM   3953  O O   . GLU B 1 41  ? -72.713 52.901  17.461 1.00 105.15 ? 49  GLU B O   1 
ATOM   3954  C CB  . GLU B 1 41  ? -73.858 53.944  20.121 1.00 96.43  ? 49  GLU B CB  1 
ATOM   3955  C CG  . GLU B 1 41  ? -72.752 54.862  20.636 1.00 98.10  ? 49  GLU B CG  1 
ATOM   3956  C CD  . GLU B 1 41  ? -73.318 55.758  21.711 1.00 122.26 ? 49  GLU B CD  1 
ATOM   3957  O OE1 . GLU B 1 41  ? -74.507 55.686  22.024 1.00 123.81 ? 49  GLU B OE1 1 
ATOM   3958  O OE2 . GLU B 1 41  ? -72.550 56.532  22.268 1.00 152.94 ? 49  GLU B OE2 1 
ATOM   3959  N N   . LEU B 1 42  ? -72.391 55.147  17.324 1.00 68.97  ? 50  LEU B N   1 
ATOM   3960  C CA  . LEU B 1 42  ? -71.225 55.032  16.466 1.00 75.40  ? 50  LEU B CA  1 
ATOM   3961  C C   . LEU B 1 42  ? -69.978 55.624  17.134 1.00 111.43 ? 50  LEU B C   1 
ATOM   3962  O O   . LEU B 1 42  ? -68.955 55.802  16.434 1.00 111.40 ? 50  LEU B O   1 
ATOM   3963  C CB  . LEU B 1 42  ? -71.492 55.748  15.151 1.00 64.39  ? 50  LEU B CB  1 
ATOM   3964  C CG  . LEU B 1 42  ? -72.339 54.952  14.162 1.00 58.78  ? 50  LEU B CG  1 
ATOM   3965  C CD1 . LEU B 1 42  ? -73.854 55.207  14.206 1.00 55.62  ? 50  LEU B CD1 1 
ATOM   3966  C CD2 . LEU B 1 42  ? -71.710 55.232  12.790 1.00 55.65  ? 50  LEU B CD2 1 
ATOM   3967  N N   . ILE B 1 43  ? -70.047 55.914  18.459 1.00 85.42  ? 51  ILE B N   1 
ATOM   3968  C CA  . ILE B 1 43  ? -68.812 56.279  19.138 1.00 87.21  ? 51  ILE B CA  1 
ATOM   3969  C C   . ILE B 1 43  ? -67.857 55.083  19.180 1.00 96.45  ? 51  ILE B C   1 
ATOM   3970  O O   . ILE B 1 43  ? -68.154 54.057  19.816 1.00 75.81  ? 51  ILE B O   1 
ATOM   3971  C CB  . ILE B 1 43  ? -69.127 56.775  20.550 1.00 80.70  ? 51  ILE B CB  1 
ATOM   3972  C CG1 . ILE B 1 43  ? -69.899 58.084  20.471 1.00 67.79  ? 51  ILE B CG1 1 
ATOM   3973  C CG2 . ILE B 1 43  ? -67.826 56.971  21.336 1.00 106.03 ? 51  ILE B CG2 1 
ATOM   3974  C CD1 . ILE B 1 43  ? -70.293 58.562  21.877 1.00 52.07  ? 51  ILE B CD1 1 
ATOM   3975  N N   . ALA B 1 44  ? -66.689 55.229  18.528 1.00 86.14  ? 52  ALA B N   1 
ATOM   3976  C CA  . ALA B 1 44  ? -65.784 54.085  18.406 1.00 93.83  ? 52  ALA B CA  1 
ATOM   3977  C C   . ALA B 1 44  ? -65.339 53.424  19.739 1.00 98.62  ? 52  ALA B C   1 
ATOM   3978  O O   . ALA B 1 44  ? -64.912 52.262  19.761 1.00 102.99 ? 52  ALA B O   1 
ATOM   3979  C CB  . ALA B 1 44  ? -64.619 54.508  17.572 1.00 82.88  ? 52  ALA B CB  1 
ATOM   3980  N N   . SER B 1 45  ? -65.423 54.135  20.879 1.00 74.40  ? 53  SER B N   1 
ATOM   3981  C CA  . SER B 1 45  ? -64.964 53.585  22.149 1.00 68.75  ? 53  SER B CA  1 
ATOM   3982  C C   . SER B 1 45  ? -66.082 52.895  22.943 1.00 86.65  ? 53  SER B C   1 
ATOM   3983  O O   . SER B 1 45  ? -65.865 52.340  24.044 1.00 71.55  ? 53  SER B O   1 
ATOM   3984  C CB  . SER B 1 45  ? -64.224 54.602  22.985 1.00 78.41  ? 53  SER B CB  1 
ATOM   3985  O OG  . SER B 1 45  ? -65.037 55.738  23.193 1.00 101.78 ? 53  SER B OG  1 
ATOM   3986  N N   . GLU B 1 46  ? -67.290 52.938  22.367 1.00 101.44 ? 54  GLU B N   1 
ATOM   3987  C CA  . GLU B 1 46  ? -68.476 52.383  23.002 1.00 82.19  ? 54  GLU B CA  1 
ATOM   3988  C C   . GLU B 1 46  ? -68.734 50.958  22.541 1.00 72.04  ? 54  GLU B C   1 
ATOM   3989  O O   . GLU B 1 46  ? -68.383 50.548  21.436 1.00 92.15  ? 54  GLU B O   1 
ATOM   3990  C CB  . GLU B 1 46  ? -69.661 53.326  22.793 1.00 60.25  ? 54  GLU B CB  1 
ATOM   3991  C CG  . GLU B 1 46  ? -69.494 54.592  23.628 1.00 68.77  ? 54  GLU B CG  1 
ATOM   3992  C CD  . GLU B 1 46  ? -69.554 54.440  25.171 1.00 87.79  ? 54  GLU B CD  1 
ATOM   3993  O OE1 . GLU B 1 46  ? -69.302 53.293  25.721 1.00 85.67  ? 54  GLU B OE1 1 
ATOM   3994  O OE2 . GLU B 1 46  ? -69.868 55.490  25.822 1.00 69.84  ? 54  GLU B OE2 1 
ATOM   3995  N N   . ASN B 1 47  ? -69.401 50.238  23.441 1.00 56.69  ? 55  ASN B N   1 
ATOM   3996  C CA  . ASN B 1 47  ? -69.954 48.919  23.185 1.00 58.51  ? 55  ASN B CA  1 
ATOM   3997  C C   . ASN B 1 47  ? -71.083 48.706  24.178 1.00 71.61  ? 55  ASN B C   1 
ATOM   3998  O O   . ASN B 1 47  ? -71.240 49.519  25.087 1.00 115.69 ? 55  ASN B O   1 
ATOM   3999  C CB  . ASN B 1 47  ? -68.893 47.838  23.285 1.00 63.19  ? 55  ASN B CB  1 
ATOM   4000  C CG  . ASN B 1 47  ? -69.048 46.738  22.275 1.00 79.01  ? 55  ASN B CG  1 
ATOM   4001  O OD1 . ASN B 1 47  ? -70.148 46.217  22.076 1.00 81.64  ? 55  ASN B OD1 1 
ATOM   4002  N ND2 . ASN B 1 47  ? -67.948 46.384  21.627 1.00 119.80 ? 55  ASN B ND2 1 
ATOM   4003  N N   . PHE B 1 48  ? -71.794 47.581  24.046 1.00 82.31  ? 56  PHE B N   1 
ATOM   4004  C CA  . PHE B 1 48  ? -72.722 47.132  25.077 1.00 101.64 ? 56  PHE B CA  1 
ATOM   4005  C C   . PHE B 1 48  ? -72.168 45.861  25.718 1.00 105.68 ? 56  PHE B C   1 
ATOM   4006  O O   . PHE B 1 48  ? -71.844 44.886  25.030 1.00 76.29  ? 56  PHE B O   1 
ATOM   4007  C CB  . PHE B 1 48  ? -74.149 46.978  24.556 1.00 111.58 ? 56  PHE B CB  1 
ATOM   4008  C CG  . PHE B 1 48  ? -74.663 48.282  23.965 1.00 142.45 ? 56  PHE B CG  1 
ATOM   4009  C CD1 . PHE B 1 48  ? -74.924 49.378  24.786 1.00 148.25 ? 56  PHE B CD1 1 
ATOM   4010  C CD2 . PHE B 1 48  ? -74.829 48.435  22.593 1.00 158.64 ? 56  PHE B CD2 1 
ATOM   4011  C CE1 . PHE B 1 48  ? -75.398 50.576  24.260 1.00 155.22 ? 56  PHE B CE1 1 
ATOM   4012  C CE2 . PHE B 1 48  ? -75.320 49.637  22.067 1.00 183.57 ? 56  PHE B CE2 1 
ATOM   4013  C CZ  . PHE B 1 48  ? -75.607 50.700  22.904 1.00 174.02 ? 56  PHE B CZ  1 
ATOM   4014  N N   . ALA B 1 49  ? -72.028 45.921  27.044 1.00 106.21 ? 57  ALA B N   1 
ATOM   4015  C CA  . ALA B 1 49  ? -71.558 44.791  27.827 1.00 94.72  ? 57  ALA B CA  1 
ATOM   4016  C C   . ALA B 1 49  ? -72.683 43.765  27.923 1.00 90.98  ? 57  ALA B C   1 
ATOM   4017  O O   . ALA B 1 49  ? -73.870 44.136  28.033 1.00 69.60  ? 57  ALA B O   1 
ATOM   4018  C CB  . ALA B 1 49  ? -71.135 45.259  29.198 1.00 88.82  ? 57  ALA B CB  1 
ATOM   4019  N N   . SER B 1 50  ? -72.274 42.481  27.867 1.00 87.78  ? 58  SER B N   1 
ATOM   4020  C CA  . SER B 1 50  ? -73.192 41.353  27.976 1.00 101.90 ? 58  SER B CA  1 
ATOM   4021  C C   . SER B 1 50  ? -73.862 41.271  29.357 1.00 98.53  ? 58  SER B C   1 
ATOM   4022  O O   . SER B 1 50  ? -73.365 41.819  30.339 1.00 87.51  ? 58  SER B O   1 
ATOM   4023  C CB  . SER B 1 50  ? -72.476 40.112  27.633 1.00 83.95  ? 58  SER B CB  1 
ATOM   4024  O OG  . SER B 1 50  ? -71.496 39.848  28.619 1.00 65.97  ? 58  SER B OG  1 
ATOM   4025  N N   . ARG B 1 51  ? -75.022 40.610  29.430 1.00 96.73  ? 59  ARG B N   1 
ATOM   4026  C CA  . ARG B 1 51  ? -75.746 40.569  30.693 1.00 114.43 ? 59  ARG B CA  1 
ATOM   4027  C C   . ARG B 1 51  ? -74.907 39.819  31.706 1.00 101.71 ? 59  ARG B C   1 
ATOM   4028  O O   . ARG B 1 51  ? -74.892 40.170  32.906 1.00 71.48  ? 59  ARG B O   1 
ATOM   4029  C CB  . ARG B 1 51  ? -77.040 39.757  30.681 1.00 151.14 ? 59  ARG B CB  1 
ATOM   4030  C CG  . ARG B 1 51  ? -78.320 40.533  30.425 1.00 164.98 ? 59  ARG B CG  1 
ATOM   4031  C CD  . ARG B 1 51  ? -79.446 39.570  30.771 1.00 172.87 ? 59  ARG B CD  1 
ATOM   4032  N NE  . ARG B 1 51  ? -78.907 38.694  31.820 1.00 136.82 ? 59  ARG B NE  1 
ATOM   4033  C CZ  . ARG B 1 51  ? -79.449 37.578  32.259 1.00 124.51 ? 59  ARG B CZ  1 
ATOM   4034  N NH1 . ARG B 1 51  ? -78.808 36.923  33.202 1.00 135.96 ? 59  ARG B NH1 1 
ATOM   4035  N NH2 . ARG B 1 51  ? -80.616 37.156  31.804 1.00 101.85 ? 59  ARG B NH2 1 
ATOM   4036  N N   . ALA B 1 52  ? -74.201 38.798  31.172 1.00 79.80  ? 60  ALA B N   1 
ATOM   4037  C CA  . ALA B 1 52  ? -73.414 37.958  32.057 1.00 94.43  ? 60  ALA B CA  1 
ATOM   4038  C C   . ALA B 1 52  ? -72.471 38.862  32.878 1.00 91.38  ? 60  ALA B C   1 
ATOM   4039  O O   . ALA B 1 52  ? -72.428 38.805  34.120 1.00 56.46  ? 60  ALA B O   1 
ATOM   4040  C CB  . ALA B 1 52  ? -72.745 36.888  31.213 1.00 76.31  ? 60  ALA B CB  1 
ATOM   4041  N N   . VAL B 1 53  ? -71.771 39.757  32.154 1.00 99.56  ? 61  VAL B N   1 
ATOM   4042  C CA  . VAL B 1 53  ? -70.764 40.641  32.722 1.00 82.61  ? 61  VAL B CA  1 
ATOM   4043  C C   . VAL B 1 53  ? -71.396 41.570  33.746 1.00 85.26  ? 61  VAL B C   1 
ATOM   4044  O O   . VAL B 1 53  ? -70.924 41.631  34.878 1.00 94.46  ? 61  VAL B O   1 
ATOM   4045  C CB  . VAL B 1 53  ? -70.089 41.476  31.631 1.00 81.07  ? 61  VAL B CB  1 
ATOM   4046  C CG1 . VAL B 1 53  ? -69.230 42.550  32.258 1.00 79.11  ? 61  VAL B CG1 1 
ATOM   4047  C CG2 . VAL B 1 53  ? -69.296 40.601  30.673 1.00 100.30 ? 61  VAL B CG2 1 
ATOM   4048  N N   . LEU B 1 54  ? -72.467 42.264  33.335 1.00 77.74  ? 62  LEU B N   1 
ATOM   4049  C CA  . LEU B 1 54  ? -73.143 43.171  34.242 1.00 70.47  ? 62  LEU B CA  1 
ATOM   4050  C C   . LEU B 1 54  ? -73.606 42.400  35.479 1.00 89.25  ? 62  LEU B C   1 
ATOM   4051  O O   . LEU B 1 54  ? -73.578 42.957  36.589 1.00 90.63  ? 62  LEU B O   1 
ATOM   4052  C CB  . LEU B 1 54  ? -74.328 43.847  33.563 1.00 57.22  ? 62  LEU B CB  1 
ATOM   4053  C CG  . LEU B 1 54  ? -74.071 44.518  32.223 1.00 79.33  ? 62  LEU B CG  1 
ATOM   4054  C CD1 . LEU B 1 54  ? -75.450 44.606  31.600 1.00 89.57  ? 62  LEU B CD1 1 
ATOM   4055  C CD2 . LEU B 1 54  ? -73.492 45.886  32.507 1.00 103.87 ? 62  LEU B CD2 1 
ATOM   4056  N N   . GLU B 1 55  ? -74.033 41.129  35.300 1.00 69.24  ? 63  GLU B N   1 
ATOM   4057  C CA  . GLU B 1 55  ? -74.505 40.372  36.448 1.00 80.53  ? 63  GLU B CA  1 
ATOM   4058  C C   . GLU B 1 55  ? -73.384 40.225  37.479 1.00 87.99  ? 63  GLU B C   1 
ATOM   4059  O O   . GLU B 1 55  ? -73.601 40.408  38.686 1.00 90.95  ? 63  GLU B O   1 
ATOM   4060  C CB  . GLU B 1 55  ? -75.105 39.026  36.048 1.00 83.99  ? 63  GLU B CB  1 
ATOM   4061  C CG  . GLU B 1 55  ? -76.403 39.118  35.258 1.00 95.48  ? 63  GLU B CG  1 
ATOM   4062  C CD  . GLU B 1 55  ? -77.422 38.036  35.597 1.00 104.76 ? 63  GLU B CD  1 
ATOM   4063  O OE1 . GLU B 1 55  ? -77.126 36.805  35.644 1.00 110.02 ? 63  GLU B OE1 1 
ATOM   4064  O OE2 . GLU B 1 55  ? -78.566 38.491  35.798 1.00 70.02  ? 63  GLU B OE2 1 
ATOM   4065  N N   . ALA B 1 56  ? -72.178 39.919  36.992 1.00 77.10  ? 64  ALA B N   1 
ATOM   4066  C CA  . ALA B 1 56  ? -71.011 39.741  37.834 1.00 65.19  ? 64  ALA B CA  1 
ATOM   4067  C C   . ALA B 1 56  ? -70.604 41.049  38.522 1.00 78.84  ? 64  ALA B C   1 
ATOM   4068  O O   . ALA B 1 56  ? -70.265 40.998  39.706 1.00 107.85 ? 64  ALA B O   1 
ATOM   4069  C CB  . ALA B 1 56  ? -69.899 39.203  36.974 1.00 75.52  ? 64  ALA B CB  1 
ATOM   4070  N N   . LEU B 1 57  ? -70.637 42.200  37.801 1.00 75.38  ? 65  LEU B N   1 
ATOM   4071  C CA  . LEU B 1 57  ? -70.385 43.535  38.347 1.00 96.81  ? 65  LEU B CA  1 
ATOM   4072  C C   . LEU B 1 57  ? -71.225 43.840  39.593 1.00 122.91 ? 65  LEU B C   1 
ATOM   4073  O O   . LEU B 1 57  ? -70.758 44.562  40.462 1.00 138.74 ? 65  LEU B O   1 
ATOM   4074  C CB  . LEU B 1 57  ? -70.723 44.622  37.329 1.00 99.08  ? 65  LEU B CB  1 
ATOM   4075  C CG  . LEU B 1 57  ? -69.584 45.326  36.592 1.00 93.44  ? 65  LEU B CG  1 
ATOM   4076  C CD1 . LEU B 1 57  ? -70.070 46.725  36.254 1.00 73.38  ? 65  LEU B CD1 1 
ATOM   4077  C CD2 . LEU B 1 57  ? -68.413 45.458  37.501 1.00 95.18  ? 65  LEU B CD2 1 
ATOM   4078  N N   . GLY B 1 58  ? -72.483 43.373  39.615 1.00 129.45 ? 66  GLY B N   1 
ATOM   4079  C CA  . GLY B 1 58  ? -73.427 43.638  40.691 1.00 100.13 ? 66  GLY B CA  1 
ATOM   4080  C C   . GLY B 1 58  ? -73.124 42.847  41.963 1.00 114.32 ? 66  GLY B C   1 
ATOM   4081  O O   . GLY B 1 58  ? -73.651 43.215  43.011 1.00 132.97 ? 66  GLY B O   1 
ATOM   4082  N N   . SER B 1 59  ? -72.227 41.842  41.902 1.00 116.79 ? 67  SER B N   1 
ATOM   4083  C CA  . SER B 1 59  ? -72.103 40.834  42.965 1.00 128.76 ? 67  SER B CA  1 
ATOM   4084  C C   . SER B 1 59  ? -71.457 41.349  44.257 1.00 111.28 ? 67  SER B C   1 
ATOM   4085  O O   . SER B 1 59  ? -70.884 42.452  44.289 1.00 83.09  ? 67  SER B O   1 
ATOM   4086  C CB  . SER B 1 59  ? -71.385 39.613  42.476 1.00 141.69 ? 67  SER B CB  1 
ATOM   4087  O OG  . SER B 1 59  ? -70.044 39.961  42.157 1.00 165.76 ? 67  SER B OG  1 
ATOM   4088  N N   . CYS B 1 60  ? -71.553 40.496  45.298 1.00 96.69  ? 68  CYS B N   1 
ATOM   4089  C CA  . CYS B 1 60  ? -70.988 40.742  46.627 1.00 106.67 ? 68  CYS B CA  1 
ATOM   4090  C C   . CYS B 1 60  ? -69.459 40.743  46.608 1.00 108.64 ? 68  CYS B C   1 
ATOM   4091  O O   . CYS B 1 60  ? -68.843 40.994  47.644 1.00 124.25 ? 68  CYS B O   1 
ATOM   4092  C CB  . CYS B 1 60  ? -71.354 39.651  47.631 1.00 81.32  ? 68  CYS B CB  1 
ATOM   4093  S SG  . CYS B 1 60  ? -70.871 38.013  47.028 1.00 98.60  ? 68  CYS B SG  1 
ATOM   4094  N N   . LEU B 1 61  ? -68.856 40.442  45.438 1.00 92.80  ? 69  LEU B N   1 
ATOM   4095  C CA  . LEU B 1 61  ? -67.409 40.419  45.293 1.00 72.99  ? 69  LEU B CA  1 
ATOM   4096  C C   . LEU B 1 61  ? -66.875 41.809  45.637 1.00 84.59  ? 69  LEU B C   1 
ATOM   4097  O O   . LEU B 1 61  ? -65.687 41.980  45.934 1.00 83.39  ? 69  LEU B O   1 
ATOM   4098  C CB  . LEU B 1 61  ? -67.030 39.985  43.874 1.00 61.12  ? 69  LEU B CB  1 
ATOM   4099  C CG  . LEU B 1 61  ? -67.346 38.537  43.501 1.00 58.11  ? 69  LEU B CG  1 
ATOM   4100  C CD1 . LEU B 1 61  ? -67.049 38.250  42.045 1.00 56.19  ? 69  LEU B CD1 1 
ATOM   4101  C CD2 . LEU B 1 61  ? -66.431 37.720  44.390 1.00 72.53  ? 69  LEU B CD2 1 
ATOM   4102  N N   . ASN B 1 62  ? -67.782 42.799  45.558 1.00 90.50  ? 70  ASN B N   1 
ATOM   4103  C CA  . ASN B 1 62  ? -67.452 44.186  45.837 1.00 98.69  ? 70  ASN B CA  1 
ATOM   4104  C C   . ASN B 1 62  ? -66.802 44.289  47.224 1.00 98.49  ? 70  ASN B C   1 
ATOM   4105  O O   . ASN B 1 62  ? -65.919 45.124  47.450 1.00 93.53  ? 70  ASN B O   1 
ATOM   4106  C CB  . ASN B 1 62  ? -68.657 45.119  45.661 1.00 88.95  ? 70  ASN B CB  1 
ATOM   4107  C CG  . ASN B 1 62  ? -68.516 46.334  46.564 1.00 118.51 ? 70  ASN B CG  1 
ATOM   4108  O OD1 . ASN B 1 62  ? -68.696 46.231  47.794 1.00 132.85 ? 70  ASN B OD1 1 
ATOM   4109  N ND2 . ASN B 1 62  ? -68.050 47.447  46.014 1.00 84.13  ? 70  ASN B ND2 1 
ATOM   4110  N N   . ASN B 1 63  ? -67.279 43.426  48.135 1.00 100.30 ? 71  ASN B N   1 
ATOM   4111  C CA  . ASN B 1 63  ? -67.126 43.575  49.569 1.00 106.15 ? 71  ASN B CA  1 
ATOM   4112  C C   . ASN B 1 63  ? -65.752 43.176  50.089 1.00 90.45  ? 71  ASN B C   1 
ATOM   4113  O O   . ASN B 1 63  ? -65.284 43.782  51.065 1.00 114.40 ? 71  ASN B O   1 
ATOM   4114  C CB  . ASN B 1 63  ? -68.247 42.852  50.300 1.00 111.45 ? 71  ASN B CB  1 
ATOM   4115  C CG  . ASN B 1 63  ? -69.547 43.605  50.133 1.00 113.46 ? 71  ASN B CG  1 
ATOM   4116  O OD1 . ASN B 1 63  ? -69.550 44.840  49.976 1.00 116.98 ? 71  ASN B OD1 1 
ATOM   4117  N ND2 . ASN B 1 63  ? -70.648 42.872  50.139 1.00 102.48 ? 71  ASN B ND2 1 
ATOM   4118  N N   . LYS B 1 64  ? -65.130 42.205  49.417 1.00 66.32  ? 72  LYS B N   1 
ATOM   4119  C CA  . LYS B 1 64  ? -63.829 41.674  49.811 1.00 80.32  ? 72  LYS B CA  1 
ATOM   4120  C C   . LYS B 1 64  ? -62.624 42.568  49.443 1.00 105.46 ? 72  LYS B C   1 
ATOM   4121  O O   . LYS B 1 64  ? -62.409 42.983  48.279 1.00 109.89 ? 72  LYS B O   1 
ATOM   4122  C CB  . LYS B 1 64  ? -63.642 40.248  49.266 1.00 69.01  ? 72  LYS B CB  1 
ATOM   4123  C CG  . LYS B 1 64  ? -62.400 39.539  49.814 1.00 77.55  ? 72  LYS B CG  1 
ATOM   4124  C CD  . LYS B 1 64  ? -62.498 39.392  51.336 1.00 102.76 ? 72  LYS B CD  1 
ATOM   4125  C CE  . LYS B 1 64  ? -61.318 38.834  52.069 1.00 111.05 ? 72  LYS B CE  1 
ATOM   4126  N NZ  . LYS B 1 64  ? -61.594 38.828  53.514 1.00 114.19 ? 72  LYS B NZ  1 
ATOM   4127  N N   . TYR B 1 65  ? -61.787 42.788  50.474 1.00 83.41  ? 73  TYR B N   1 
ATOM   4128  C CA  . TYR B 1 65  ? -60.533 43.490  50.267 1.00 86.63  ? 73  TYR B CA  1 
ATOM   4129  C C   . TYR B 1 65  ? -59.495 42.425  49.945 1.00 85.24  ? 73  TYR B C   1 
ATOM   4130  O O   . TYR B 1 65  ? -59.326 41.531  50.765 1.00 81.75  ? 73  TYR B O   1 
ATOM   4131  C CB  . TYR B 1 65  ? -60.169 44.287  51.531 1.00 79.19  ? 73  TYR B CB  1 
ATOM   4132  C CG  . TYR B 1 65  ? -60.010 45.782  51.264 1.00 72.93  ? 73  TYR B CG  1 
ATOM   4133  C CD1 . TYR B 1 65  ? -59.009 46.282  50.432 1.00 80.12  ? 73  TYR B CD1 1 
ATOM   4134  C CD2 . TYR B 1 65  ? -60.870 46.711  51.832 1.00 62.81  ? 73  TYR B CD2 1 
ATOM   4135  C CE1 . TYR B 1 65  ? -58.895 47.636  50.150 1.00 78.32  ? 73  TYR B CE1 1 
ATOM   4136  C CE2 . TYR B 1 65  ? -60.764 48.069  51.555 1.00 68.36  ? 73  TYR B CE2 1 
ATOM   4137  C CZ  . TYR B 1 65  ? -59.799 48.536  50.675 1.00 78.58  ? 73  TYR B CZ  1 
ATOM   4138  O OH  . TYR B 1 65  ? -59.706 49.875  50.410 1.00 94.82  ? 73  TYR B OH  1 
ATOM   4139  N N   . SER B 1 66  ? -58.808 42.534  48.799 1.00 73.33  ? 74  SER B N   1 
ATOM   4140  C CA  . SER B 1 66  ? -57.801 41.515  48.512 1.00 72.98  ? 74  SER B CA  1 
ATOM   4141  C C   . SER B 1 66  ? -56.445 42.092  48.084 1.00 87.68  ? 74  SER B C   1 
ATOM   4142  O O   . SER B 1 66  ? -55.892 41.701  47.043 1.00 152.10 ? 74  SER B O   1 
ATOM   4143  C CB  . SER B 1 66  ? -58.302 40.498  47.501 1.00 66.83  ? 74  SER B CB  1 
ATOM   4144  O OG  . SER B 1 66  ? -58.697 41.124  46.283 1.00 76.24  ? 74  SER B OG  1 
ATOM   4145  N N   . GLU B 1 67  ? -55.905 43.000  48.899 1.00 71.99  ? 75  GLU B N   1 
ATOM   4146  C CA  . GLU B 1 67  ? -54.718 43.730  48.470 1.00 94.42  ? 75  GLU B CA  1 
ATOM   4147  C C   . GLU B 1 67  ? -53.550 42.783  48.203 1.00 92.59  ? 75  GLU B C   1 
ATOM   4148  O O   . GLU B 1 67  ? -53.265 41.892  49.017 1.00 84.73  ? 75  GLU B O   1 
ATOM   4149  C CB  . GLU B 1 67  ? -54.344 44.824  49.471 1.00 83.76  ? 75  GLU B CB  1 
ATOM   4150  C CG  . GLU B 1 67  ? -55.057 46.135  49.168 1.00 61.69  ? 75  GLU B CG  1 
ATOM   4151  C CD  . GLU B 1 67  ? -54.996 47.060  50.344 1.00 76.05  ? 75  GLU B CD  1 
ATOM   4152  O OE1 . GLU B 1 67  ? -55.027 46.479  51.505 1.00 59.95  ? 75  GLU B OE1 1 
ATOM   4153  O OE2 . GLU B 1 67  ? -54.956 48.309  50.067 1.00 90.19  ? 75  GLU B OE2 1 
ATOM   4154  N N   . GLY B 1 68  ? -52.863 43.002  47.078 1.00 71.00  ? 76  GLY B N   1 
ATOM   4155  C CA  . GLY B 1 68  ? -51.754 42.093  46.882 1.00 74.74  ? 76  GLY B CA  1 
ATOM   4156  C C   . GLY B 1 68  ? -52.097 41.151  45.748 1.00 76.39  ? 76  GLY B C   1 
ATOM   4157  O O   . GLY B 1 68  ? -52.778 41.570  44.837 1.00 105.16 ? 76  GLY B O   1 
ATOM   4158  N N   . TYR B 1 69  ? -51.578 39.923  45.787 1.00 93.03  ? 77  TYR B N   1 
ATOM   4159  C CA  . TYR B 1 69  ? -51.807 38.985  44.694 1.00 102.56 ? 77  TYR B CA  1 
ATOM   4160  C C   . TYR B 1 69  ? -52.128 37.594  45.229 1.00 97.81  ? 77  TYR B C   1 
ATOM   4161  O O   . TYR B 1 69  ? -51.905 37.306  46.411 1.00 93.02  ? 77  TYR B O   1 
ATOM   4162  C CB  . TYR B 1 69  ? -50.572 38.979  43.781 1.00 66.73  ? 77  TYR B CB  1 
ATOM   4163  C CG  . TYR B 1 69  ? -50.367 40.336  43.140 1.00 67.82  ? 77  TYR B CG  1 
ATOM   4164  C CD1 . TYR B 1 69  ? -51.006 40.675  41.952 1.00 88.11  ? 77  TYR B CD1 1 
ATOM   4165  C CD2 . TYR B 1 69  ? -49.561 41.293  43.746 1.00 84.35  ? 77  TYR B CD2 1 
ATOM   4166  C CE1 . TYR B 1 69  ? -50.853 41.940  41.402 1.00 91.67  ? 77  TYR B CE1 1 
ATOM   4167  C CE2 . TYR B 1 69  ? -49.385 42.550  43.195 1.00 91.02  ? 77  TYR B CE2 1 
ATOM   4168  C CZ  . TYR B 1 69  ? -50.018 42.866  42.011 1.00 89.29  ? 77  TYR B CZ  1 
ATOM   4169  O OH  . TYR B 1 69  ? -49.850 44.120  41.503 1.00 65.38  ? 77  TYR B OH  1 
ATOM   4170  N N   . PRO B 1 70  ? -52.663 36.693  44.369 1.00 71.87  ? 78  PRO B N   1 
ATOM   4171  C CA  . PRO B 1 70  ? -52.998 35.348  44.810 1.00 87.96  ? 78  PRO B CA  1 
ATOM   4172  C C   . PRO B 1 70  ? -51.790 34.696  45.466 1.00 113.43 ? 78  PRO B C   1 
ATOM   4173  O O   . PRO B 1 70  ? -50.724 34.668  44.847 1.00 74.72  ? 78  PRO B O   1 
ATOM   4174  C CB  . PRO B 1 70  ? -53.361 34.694  43.490 1.00 86.04  ? 78  PRO B CB  1 
ATOM   4175  C CG  . PRO B 1 70  ? -53.982 35.815  42.741 1.00 105.45 ? 78  PRO B CG  1 
ATOM   4176  C CD  . PRO B 1 70  ? -52.972 36.931  42.951 1.00 74.86  ? 78  PRO B CD  1 
ATOM   4177  N N   . GLY B 1 71  ? -51.983 34.206  46.707 1.00 125.96 ? 79  GLY B N   1 
ATOM   4178  C CA  . GLY B 1 71  ? -50.928 33.502  47.412 1.00 99.91  ? 79  GLY B CA  1 
ATOM   4179  C C   . GLY B 1 71  ? -50.033 34.463  48.170 1.00 114.76 ? 79  GLY B C   1 
ATOM   4180  O O   . GLY B 1 71  ? -49.317 34.028  49.065 1.00 167.57 ? 79  GLY B O   1 
ATOM   4181  N N   . GLN B 1 72  ? -50.094 35.772  47.848 1.00 110.52 ? 80  GLN B N   1 
ATOM   4182  C CA  . GLN B 1 72  ? -49.428 36.806  48.631 1.00 90.06  ? 80  GLN B CA  1 
ATOM   4183  C C   . GLN B 1 72  ? -50.400 37.952  48.941 1.00 81.33  ? 80  GLN B C   1 
ATOM   4184  O O   . GLN B 1 72  ? -50.213 39.082  48.503 1.00 95.98  ? 80  GLN B O   1 
ATOM   4185  C CB  . GLN B 1 72  ? -48.136 37.262  47.960 1.00 67.28  ? 80  GLN B CB  1 
ATOM   4186  C CG  . GLN B 1 72  ? -47.632 36.362  46.846 1.00 75.51  ? 80  GLN B CG  1 
ATOM   4187  C CD  . GLN B 1 72  ? -47.344 37.136  45.573 1.00 113.03 ? 80  GLN B CD  1 
ATOM   4188  O OE1 . GLN B 1 72  ? -47.454 38.371  45.557 1.00 129.75 ? 80  GLN B OE1 1 
ATOM   4189  N NE2 . GLN B 1 72  ? -46.993 36.447  44.486 1.00 97.89  ? 80  GLN B NE2 1 
ATOM   4190  N N   . ARG B 1 73  ? -51.437 37.640  49.726 1.00 66.12  ? 81  ARG B N   1 
ATOM   4191  C CA  . ARG B 1 73  ? -52.479 38.600  50.051 1.00 70.22  ? 81  ARG B CA  1 
ATOM   4192  C C   . ARG B 1 73  ? -52.132 39.288  51.358 1.00 83.96  ? 81  ARG B C   1 
ATOM   4193  O O   . ARG B 1 73  ? -51.291 38.789  52.107 1.00 150.22 ? 81  ARG B O   1 
ATOM   4194  C CB  . ARG B 1 73  ? -53.878 37.973  50.150 1.00 70.61  ? 81  ARG B CB  1 
ATOM   4195  C CG  . ARG B 1 73  ? -54.409 37.389  48.839 1.00 80.55  ? 81  ARG B CG  1 
ATOM   4196  C CD  . ARG B 1 73  ? -54.593 38.412  47.709 1.00 55.10  ? 81  ARG B CD  1 
ATOM   4197  N NE  . ARG B 1 73  ? -55.350 37.840  46.592 1.00 60.67  ? 81  ARG B NE  1 
ATOM   4198  C CZ  . ARG B 1 73  ? -55.712 38.453  45.459 1.00 75.71  ? 81  ARG B CZ  1 
ATOM   4199  N NH1 . ARG B 1 73  ? -55.368 39.720  45.219 1.00 81.81  ? 81  ARG B NH1 1 
ATOM   4200  N NH2 . ARG B 1 73  ? -56.436 37.781  44.565 1.00 50.39  ? 81  ARG B NH2 1 
ATOM   4201  N N   . TYR B 1 74  ? -52.800 40.416  51.640 1.00 97.28  ? 82  TYR B N   1 
ATOM   4202  C CA  . TYR B 1 74  ? -52.561 41.099  52.901 1.00 98.92  ? 82  TYR B CA  1 
ATOM   4203  C C   . TYR B 1 74  ? -53.810 41.010  53.760 1.00 114.86 ? 82  TYR B C   1 
ATOM   4204  O O   . TYR B 1 74  ? -53.768 41.355  54.932 1.00 143.79 ? 82  TYR B O   1 
ATOM   4205  C CB  . TYR B 1 74  ? -52.119 42.557  52.834 1.00 81.54  ? 82  TYR B CB  1 
ATOM   4206  C CG  . TYR B 1 74  ? -50.765 42.873  52.218 1.00 76.42  ? 82  TYR B CG  1 
ATOM   4207  C CD1 . TYR B 1 74  ? -49.908 41.873  51.736 1.00 89.34  ? 82  TYR B CD1 1 
ATOM   4208  C CD2 . TYR B 1 74  ? -50.358 44.204  52.100 1.00 79.92  ? 82  TYR B CD2 1 
ATOM   4209  C CE1 . TYR B 1 74  ? -48.699 42.181  51.131 1.00 99.11  ? 82  TYR B CE1 1 
ATOM   4210  C CE2 . TYR B 1 74  ? -49.146 44.529  51.507 1.00 107.25 ? 82  TYR B CE2 1 
ATOM   4211  C CZ  . TYR B 1 74  ? -48.326 43.513  51.018 1.00 109.74 ? 82  TYR B CZ  1 
ATOM   4212  O OH  . TYR B 1 74  ? -47.125 43.811  50.449 1.00 108.41 ? 82  TYR B OH  1 
ATOM   4213  N N   . TYR B 1 75  ? -54.885 40.483  53.171 1.00 121.03 ? 83  TYR B N   1 
ATOM   4214  C CA  . TYR B 1 75  ? -56.059 40.143  53.958 1.00 111.30 ? 83  TYR B CA  1 
ATOM   4215  C C   . TYR B 1 75  ? -56.325 38.640  53.844 1.00 89.77  ? 83  TYR B C   1 
ATOM   4216  O O   . TYR B 1 75  ? -55.997 38.038  52.824 1.00 111.34 ? 83  TYR B O   1 
ATOM   4217  C CB  . TYR B 1 75  ? -57.213 41.024  53.482 1.00 110.44 ? 83  TYR B CB  1 
ATOM   4218  C CG  . TYR B 1 75  ? -57.104 42.525  53.733 1.00 148.87 ? 83  TYR B CG  1 
ATOM   4219  C CD1 . TYR B 1 75  ? -57.178 43.061  55.021 1.00 156.97 ? 83  TYR B CD1 1 
ATOM   4220  C CD2 . TYR B 1 75  ? -57.004 43.418  52.671 1.00 143.28 ? 83  TYR B CD2 1 
ATOM   4221  C CE1 . TYR B 1 75  ? -57.141 44.435  55.243 1.00 144.00 ? 83  TYR B CE1 1 
ATOM   4222  C CE2 . TYR B 1 75  ? -56.977 44.792  52.875 1.00 141.15 ? 83  TYR B CE2 1 
ATOM   4223  C CZ  . TYR B 1 75  ? -57.057 45.314  54.163 1.00 144.28 ? 83  TYR B CZ  1 
ATOM   4224  O OH  . TYR B 1 75  ? -57.073 46.689  54.367 1.00 78.90  ? 83  TYR B OH  1 
ATOM   4225  N N   . GLY B 1 76  ? -56.888 38.026  54.899 1.00 65.97  ? 84  GLY B N   1 
ATOM   4226  C CA  . GLY B 1 76  ? -57.319 36.634  54.864 1.00 74.13  ? 84  GLY B CA  1 
ATOM   4227  C C   . GLY B 1 76  ? -58.591 36.406  54.029 1.00 109.40 ? 84  GLY B C   1 
ATOM   4228  O O   . GLY B 1 76  ? -59.236 37.344  53.548 1.00 109.22 ? 84  GLY B O   1 
ATOM   4229  N N   . GLY B 1 77  ? -58.936 35.128  53.823 1.00 129.40 ? 85  GLY B N   1 
ATOM   4230  C CA  . GLY B 1 77  ? -60.252 34.713  53.353 1.00 129.36 ? 85  GLY B CA  1 
ATOM   4231  C C   . GLY B 1 77  ? -60.418 34.872  51.846 1.00 124.81 ? 85  GLY B C   1 
ATOM   4232  O O   . GLY B 1 77  ? -61.453 34.581  51.240 1.00 121.46 ? 85  GLY B O   1 
ATOM   4233  N N   . THR B 1 78  ? -59.333 35.258  51.214 1.00 108.11 ? 86  THR B N   1 
ATOM   4234  C CA  . THR B 1 78  ? -59.373 35.501  49.792 1.00 123.40 ? 86  THR B CA  1 
ATOM   4235  C C   . THR B 1 78  ? -59.435 34.204  49.000 1.00 104.31 ? 86  THR B C   1 
ATOM   4236  O O   . THR B 1 78  ? -59.149 34.230  47.818 1.00 126.17 ? 86  THR B O   1 
ATOM   4237  C CB  . THR B 1 78  ? -58.122 36.306  49.482 1.00 141.77 ? 86  THR B CB  1 
ATOM   4238  O OG1 . THR B 1 78  ? -56.956 35.536  49.776 1.00 91.54  ? 86  THR B OG1 1 
ATOM   4239  C CG2 . THR B 1 78  ? -58.130 37.591  50.288 1.00 140.40 ? 86  THR B CG2 1 
ATOM   4240  N N   . GLU B 1 79  ? -59.835 33.096  49.621 1.00 120.29 ? 87  GLU B N   1 
ATOM   4241  C CA  . GLU B 1 79  ? -59.845 31.814  48.931 1.00 143.20 ? 87  GLU B CA  1 
ATOM   4242  C C   . GLU B 1 79  ? -60.620 31.908  47.606 1.00 132.88 ? 87  GLU B C   1 
ATOM   4243  O O   . GLU B 1 79  ? -60.160 31.396  46.572 1.00 126.28 ? 87  GLU B O   1 
ATOM   4244  C CB  . GLU B 1 79  ? -60.314 30.674  49.835 1.00 146.11 ? 87  GLU B CB  1 
ATOM   4245  C CG  . GLU B 1 79  ? -60.529 29.392  49.029 1.00 130.86 ? 87  GLU B CG  1 
ATOM   4246  C CD  . GLU B 1 79  ? -61.255 28.287  49.755 1.00 131.98 ? 87  GLU B CD  1 
ATOM   4247  O OE1 . GLU B 1 79  ? -62.311 28.700  50.256 1.00 130.93 ? 87  GLU B OE1 1 
ATOM   4248  O OE2 . GLU B 1 79  ? -60.851 27.089  49.823 1.00 130.64 ? 87  GLU B OE2 1 
ATOM   4249  N N   . PHE B 1 80  ? -61.799 32.567  47.637 1.00 88.56  ? 88  PHE B N   1 
ATOM   4250  C CA  . PHE B 1 80  ? -62.624 32.631  46.438 1.00 90.00  ? 88  PHE B CA  1 
ATOM   4251  C C   . PHE B 1 80  ? -62.121 33.720  45.493 1.00 105.00 ? 88  PHE B C   1 
ATOM   4252  O O   . PHE B 1 80  ? -62.169 33.560  44.273 1.00 85.21  ? 88  PHE B O   1 
ATOM   4253  C CB  . PHE B 1 80  ? -64.135 32.624  46.676 1.00 85.51  ? 88  PHE B CB  1 
ATOM   4254  C CG  . PHE B 1 80  ? -64.501 31.391  47.486 1.00 98.50  ? 88  PHE B CG  1 
ATOM   4255  C CD1 . PHE B 1 80  ? -64.153 30.112  47.034 1.00 95.25  ? 88  PHE B CD1 1 
ATOM   4256  C CD2 . PHE B 1 80  ? -65.011 31.523  48.783 1.00 105.12 ? 88  PHE B CD2 1 
ATOM   4257  C CE1 . PHE B 1 80  ? -64.410 29.002  47.821 1.00 83.44  ? 88  PHE B CE1 1 
ATOM   4258  C CE2 . PHE B 1 80  ? -65.266 30.412  49.576 1.00 88.84  ? 88  PHE B CE2 1 
ATOM   4259  C CZ  . PHE B 1 80  ? -64.963 29.155  49.080 1.00 90.39  ? 88  PHE B CZ  1 
ATOM   4260  N N   . ILE B 1 81  ? -61.650 34.830  46.070 1.00 101.96 ? 89  ILE B N   1 
ATOM   4261  C CA  . ILE B 1 81  ? -61.061 35.899  45.273 1.00 74.37  ? 89  ILE B CA  1 
ATOM   4262  C C   . ILE B 1 81  ? -59.864 35.336  44.512 1.00 93.63  ? 89  ILE B C   1 
ATOM   4263  O O   . ILE B 1 81  ? -59.594 35.724  43.370 1.00 107.40 ? 89  ILE B O   1 
ATOM   4264  C CB  . ILE B 1 81  ? -60.632 37.067  46.176 1.00 58.36  ? 89  ILE B CB  1 
ATOM   4265  C CG1 . ILE B 1 81  ? -61.813 37.700  46.900 1.00 67.16  ? 89  ILE B CG1 1 
ATOM   4266  C CG2 . ILE B 1 81  ? -59.792 38.109  45.431 1.00 93.51  ? 89  ILE B CG2 1 
ATOM   4267  C CD1 . ILE B 1 81  ? -63.145 37.744  46.168 1.00 63.96  ? 89  ILE B CD1 1 
ATOM   4268  N N   . ASP B 1 82  ? -59.132 34.436  45.169 1.00 73.99  ? 90  ASP B N   1 
ATOM   4269  C CA  . ASP B 1 82  ? -57.935 33.891  44.586 1.00 65.78  ? 90  ASP B CA  1 
ATOM   4270  C C   . ASP B 1 82  ? -58.318 33.036  43.392 1.00 77.99  ? 90  ASP B C   1 
ATOM   4271  O O   . ASP B 1 82  ? -57.638 33.114  42.366 1.00 67.42  ? 90  ASP B O   1 
ATOM   4272  C CB  . ASP B 1 82  ? -57.144 33.158  45.635 1.00 73.66  ? 90  ASP B CB  1 
ATOM   4273  C CG  . ASP B 1 82  ? -56.465 34.102  46.601 1.00 82.62  ? 90  ASP B CG  1 
ATOM   4274  O OD1 . ASP B 1 82  ? -56.136 35.236  46.166 1.00 81.75  ? 90  ASP B OD1 1 
ATOM   4275  O OD2 . ASP B 1 82  ? -56.186 33.634  47.717 1.00 80.82  ? 90  ASP B OD2 1 
ATOM   4276  N N   . GLU B 1 83  ? -59.413 32.269  43.525 1.00 79.82  ? 91  GLU B N   1 
ATOM   4277  C CA  . GLU B 1 83  ? -59.882 31.484  42.388 1.00 96.14  ? 91  GLU B CA  1 
ATOM   4278  C C   . GLU B 1 83  ? -60.125 32.444  41.235 1.00 111.03 ? 91  GLU B C   1 
ATOM   4279  O O   . GLU B 1 83  ? -59.667 32.223  40.118 1.00 105.30 ? 91  GLU B O   1 
ATOM   4280  C CB  . GLU B 1 83  ? -61.205 30.741  42.576 1.00 67.38  ? 91  GLU B CB  1 
ATOM   4281  C CG  . GLU B 1 83  ? -61.194 29.721  43.714 1.00 120.42 ? 91  GLU B CG  1 
ATOM   4282  C CD  . GLU B 1 83  ? -62.142 28.570  43.403 1.00 130.65 ? 91  GLU B CD  1 
ATOM   4283  O OE1 . GLU B 1 83  ? -62.706 28.595  42.253 1.00 92.45  ? 91  GLU B OE1 1 
ATOM   4284  O OE2 . GLU B 1 83  ? -62.283 27.688  44.310 1.00 112.60 ? 91  GLU B OE2 1 
ATOM   4285  N N   . LEU B 1 84  ? -60.848 33.518  41.559 1.00 116.67 ? 92  LEU B N   1 
ATOM   4286  C CA  . LEU B 1 84  ? -61.313 34.484  40.591 1.00 97.45  ? 92  LEU B CA  1 
ATOM   4287  C C   . LEU B 1 84  ? -60.140 35.133  39.874 1.00 92.81  ? 92  LEU B C   1 
ATOM   4288  O O   . LEU B 1 84  ? -60.077 35.038  38.652 1.00 84.63  ? 92  LEU B O   1 
ATOM   4289  C CB  . LEU B 1 84  ? -62.181 35.533  41.270 1.00 96.19  ? 92  LEU B CB  1 
ATOM   4290  C CG  . LEU B 1 84  ? -62.687 36.626  40.339 1.00 120.52 ? 92  LEU B CG  1 
ATOM   4291  C CD1 . LEU B 1 84  ? -63.571 35.966  39.281 1.00 119.62 ? 92  LEU B CD1 1 
ATOM   4292  C CD2 . LEU B 1 84  ? -63.512 37.571  41.203 1.00 120.51 ? 92  LEU B CD2 1 
ATOM   4293  N N   . GLU B 1 85  ? -59.247 35.790  40.632 1.00 81.70  ? 93  GLU B N   1 
ATOM   4294  C CA  . GLU B 1 85  ? -58.114 36.490  40.019 1.00 87.78  ? 93  GLU B CA  1 
ATOM   4295  C C   . GLU B 1 85  ? -57.282 35.523  39.175 1.00 78.54  ? 93  GLU B C   1 
ATOM   4296  O O   . GLU B 1 85  ? -56.909 35.819  38.039 1.00 70.81  ? 93  GLU B O   1 
ATOM   4297  C CB  . GLU B 1 85  ? -57.225 37.204  41.034 1.00 70.01  ? 93  GLU B CB  1 
ATOM   4298  C CG  . GLU B 1 85  ? -55.985 37.885  40.447 1.00 61.71  ? 93  GLU B CG  1 
ATOM   4299  C CD  . GLU B 1 85  ? -55.505 39.112  41.237 1.00 97.30  ? 93  GLU B CD  1 
ATOM   4300  O OE1 . GLU B 1 85  ? -55.946 39.342  42.402 1.00 93.88  ? 93  GLU B OE1 1 
ATOM   4301  O OE2 . GLU B 1 85  ? -54.728 39.930  40.674 1.00 106.98 ? 93  GLU B OE2 1 
ATOM   4302  N N   . THR B 1 86  ? -57.021 34.340  39.732 1.00 67.93  ? 94  THR B N   1 
ATOM   4303  C CA  . THR B 1 86  ? -56.234 33.339  39.037 1.00 67.13  ? 94  THR B CA  1 
ATOM   4304  C C   . THR B 1 86  ? -56.948 32.964  37.742 1.00 62.63  ? 94  THR B C   1 
ATOM   4305  O O   . THR B 1 86  ? -56.346 32.978  36.659 1.00 39.96  ? 94  THR B O   1 
ATOM   4306  C CB  . THR B 1 86  ? -56.057 32.157  39.996 1.00 57.97  ? 94  THR B CB  1 
ATOM   4307  O OG1 . THR B 1 86  ? -55.059 32.602  40.923 1.00 96.28  ? 94  THR B OG1 1 
ATOM   4308  C CG2 . THR B 1 86  ? -55.636 30.871  39.334 1.00 38.95  ? 94  THR B CG2 1 
ATOM   4309  N N   . LEU B 1 87  ? -58.242 32.641  37.885 1.00 71.08  ? 95  LEU B N   1 
ATOM   4310  C CA  . LEU B 1 87  ? -59.057 32.247  36.744 1.00 68.57  ? 95  LEU B CA  1 
ATOM   4311  C C   . LEU B 1 87  ? -58.931 33.334  35.679 1.00 75.40  ? 95  LEU B C   1 
ATOM   4312  O O   . LEU B 1 87  ? -58.658 33.055  34.513 1.00 70.67  ? 95  LEU B O   1 
ATOM   4313  C CB  . LEU B 1 87  ? -60.516 32.010  37.153 1.00 55.49  ? 95  LEU B CB  1 
ATOM   4314  C CG  . LEU B 1 87  ? -61.527 31.780  36.026 1.00 73.85  ? 95  LEU B CG  1 
ATOM   4315  C CD1 . LEU B 1 87  ? -61.241 30.577  35.189 1.00 95.22  ? 95  LEU B CD1 1 
ATOM   4316  C CD2 . LEU B 1 87  ? -62.882 31.545  36.628 1.00 92.54  ? 95  LEU B CD2 1 
ATOM   4317  N N   . CYS B 1 88  ? -59.132 34.586  36.104 1.00 75.23  ? 96  CYS B N   1 
ATOM   4318  C CA  . CYS B 1 88  ? -59.115 35.702  35.182 1.00 75.79  ? 96  CYS B CA  1 
ATOM   4319  C C   . CYS B 1 88  ? -57.792 35.755  34.425 1.00 79.76  ? 96  CYS B C   1 
ATOM   4320  O O   . CYS B 1 88  ? -57.803 35.895  33.201 1.00 77.17  ? 96  CYS B O   1 
ATOM   4321  C CB  . CYS B 1 88  ? -59.310 37.027  35.896 1.00 74.69  ? 96  CYS B CB  1 
ATOM   4322  S SG  . CYS B 1 88  ? -59.876 38.275  34.717 1.00 96.08  ? 96  CYS B SG  1 
ATOM   4323  N N   . GLN B 1 89  ? -56.669 35.664  35.150 1.00 71.80  ? 97  GLN B N   1 
ATOM   4324  C CA  . GLN B 1 89  ? -55.348 35.740  34.536 1.00 66.60  ? 97  GLN B CA  1 
ATOM   4325  C C   . GLN B 1 89  ? -55.195 34.621  33.502 1.00 81.74  ? 97  GLN B C   1 
ATOM   4326  O O   . GLN B 1 89  ? -54.651 34.852  32.397 1.00 63.36  ? 97  GLN B O   1 
ATOM   4327  C CB  . GLN B 1 89  ? -54.213 35.596  35.543 1.00 48.52  ? 97  GLN B CB  1 
ATOM   4328  C CG  . GLN B 1 89  ? -54.060 36.765  36.496 1.00 68.40  ? 97  GLN B CG  1 
ATOM   4329  C CD  . GLN B 1 89  ? -53.235 36.367  37.708 1.00 92.39  ? 97  GLN B CD  1 
ATOM   4330  O OE1 . GLN B 1 89  ? -53.321 35.228  38.172 1.00 56.08  ? 97  GLN B OE1 1 
ATOM   4331  N NE2 . GLN B 1 89  ? -52.377 37.251  38.221 1.00 132.72 ? 97  GLN B NE2 1 
ATOM   4332  N N   . LYS B 1 90  ? -55.644 33.406  33.894 1.00 70.65  ? 98  LYS B N   1 
ATOM   4333  C CA  . LYS B 1 90  ? -55.550 32.256  33.017 1.00 69.75  ? 98  LYS B CA  1 
ATOM   4334  C C   . LYS B 1 90  ? -56.305 32.559  31.716 1.00 76.72  ? 98  LYS B C   1 
ATOM   4335  O O   . LYS B 1 90  ? -55.750 32.367  30.626 1.00 72.43  ? 98  LYS B O   1 
ATOM   4336  C CB  . LYS B 1 90  ? -56.007 31.009  33.773 1.00 61.70  ? 98  LYS B CB  1 
ATOM   4337  C CG  . LYS B 1 90  ? -56.142 29.734  32.929 1.00 79.20  ? 98  LYS B CG  1 
ATOM   4338  C CD  . LYS B 1 90  ? -56.446 28.558  33.878 1.00 126.69 ? 98  LYS B CD  1 
ATOM   4339  C CE  . LYS B 1 90  ? -57.852 28.368  34.452 1.00 124.52 ? 98  LYS B CE  1 
ATOM   4340  N NZ  . LYS B 1 90  ? -58.786 28.095  33.348 1.00 93.93  ? 98  LYS B NZ  1 
ATOM   4341  N N   . ARG B 1 91  ? -57.541 33.088  31.840 1.00 49.76  ? 99  ARG B N   1 
ATOM   4342  C CA  . ARG B 1 91  ? -58.374 33.334  30.677 1.00 73.13  ? 99  ARG B CA  1 
ATOM   4343  C C   . ARG B 1 91  ? -57.785 34.452  29.812 1.00 85.56  ? 99  ARG B C   1 
ATOM   4344  O O   . ARG B 1 91  ? -57.812 34.413  28.573 1.00 68.72  ? 99  ARG B O   1 
ATOM   4345  C CB  . ARG B 1 91  ? -59.799 33.675  31.094 1.00 81.29  ? 99  ARG B CB  1 
ATOM   4346  C CG  . ARG B 1 91  ? -60.559 32.525  31.736 1.00 84.25  ? 99  ARG B CG  1 
ATOM   4347  C CD  . ARG B 1 91  ? -61.976 32.982  32.019 1.00 89.54  ? 99  ARG B CD  1 
ATOM   4348  N NE  . ARG B 1 91  ? -62.813 31.893  32.510 1.00 86.32  ? 99  ARG B NE  1 
ATOM   4349  C CZ  . ARG B 1 91  ? -64.056 32.027  32.908 1.00 102.95 ? 99  ARG B CZ  1 
ATOM   4350  N NH1 . ARG B 1 91  ? -64.564 33.216  33.061 1.00 106.78 ? 99  ARG B NH1 1 
ATOM   4351  N NH2 . ARG B 1 91  ? -64.765 30.975  33.264 1.00 132.43 ? 99  ARG B NH2 1 
ATOM   4352  N N   . ALA B 1 92  ? -57.219 35.450  30.477 1.00 86.41  ? 100 ALA B N   1 
ATOM   4353  C CA  . ALA B 1 92  ? -56.630 36.554  29.744 1.00 95.29  ? 100 ALA B CA  1 
ATOM   4354  C C   . ALA B 1 92  ? -55.485 36.041  28.869 1.00 114.91 ? 100 ALA B C   1 
ATOM   4355  O O   . ALA B 1 92  ? -55.405 36.424  27.696 1.00 161.64 ? 100 ALA B O   1 
ATOM   4356  C CB  . ALA B 1 92  ? -56.201 37.624  30.713 1.00 74.48  ? 100 ALA B CB  1 
ATOM   4357  N N   . LEU B 1 93  ? -54.579 35.226  29.450 1.00 88.29  ? 101 LEU B N   1 
ATOM   4358  C CA  . LEU B 1 93  ? -53.449 34.713  28.689 1.00 111.63 ? 101 LEU B CA  1 
ATOM   4359  C C   . LEU B 1 93  ? -53.963 33.836  27.544 1.00 123.12 ? 101 LEU B C   1 
ATOM   4360  O O   . LEU B 1 93  ? -53.428 33.841  26.432 1.00 104.16 ? 101 LEU B O   1 
ATOM   4361  C CB  . LEU B 1 93  ? -52.469 33.950  29.580 1.00 110.99 ? 101 LEU B CB  1 
ATOM   4362  C CG  . LEU B 1 93  ? -51.753 34.736  30.673 1.00 98.16  ? 101 LEU B CG  1 
ATOM   4363  C CD1 . LEU B 1 93  ? -50.811 33.786  31.337 1.00 106.90 ? 101 LEU B CD1 1 
ATOM   4364  C CD2 . LEU B 1 93  ? -50.875 35.793  30.086 1.00 96.03  ? 101 LEU B CD2 1 
ATOM   4365  N N   . GLN B 1 94  ? -55.024 33.073  27.843 1.00 92.93  ? 102 GLN B N   1 
ATOM   4366  C CA  . GLN B 1 94  ? -55.583 32.146  26.879 1.00 94.31  ? 102 GLN B CA  1 
ATOM   4367  C C   . GLN B 1 94  ? -56.173 32.926  25.714 1.00 105.41 ? 102 GLN B C   1 
ATOM   4368  O O   . GLN B 1 94  ? -55.775 32.692  24.579 1.00 102.11 ? 102 GLN B O   1 
ATOM   4369  C CB  . GLN B 1 94  ? -56.662 31.279  27.500 1.00 77.06  ? 102 GLN B CB  1 
ATOM   4370  C CG  . GLN B 1 94  ? -56.263 29.837  27.760 1.00 98.45  ? 102 GLN B CG  1 
ATOM   4371  C CD  . GLN B 1 94  ? -57.487 29.190  28.347 1.00 122.83 ? 102 GLN B CD  1 
ATOM   4372  O OE1 . GLN B 1 94  ? -57.582 28.921  29.560 1.00 137.06 ? 102 GLN B OE1 1 
ATOM   4373  N NE2 . GLN B 1 94  ? -58.485 29.161  27.471 1.00 75.07  ? 102 GLN B NE2 1 
ATOM   4374  N N   . ALA B 1 95  ? -57.082 33.866  26.001 1.00 88.54  ? 103 ALA B N   1 
ATOM   4375  C CA  . ALA B 1 95  ? -57.766 34.628  24.968 1.00 87.83  ? 103 ALA B CA  1 
ATOM   4376  C C   . ALA B 1 95  ? -56.801 35.124  23.895 1.00 92.17  ? 103 ALA B C   1 
ATOM   4377  O O   . ALA B 1 95  ? -57.147 35.196  22.709 1.00 88.01  ? 103 ALA B O   1 
ATOM   4378  C CB  . ALA B 1 95  ? -58.525 35.759  25.611 1.00 99.17  ? 103 ALA B CB  1 
ATOM   4379  N N   . TYR B 1 96  ? -55.573 35.451  24.332 1.00 81.75  ? 104 TYR B N   1 
ATOM   4380  C CA  . TYR B 1 96  ? -54.592 36.014  23.417 1.00 87.71  ? 104 TYR B CA  1 
ATOM   4381  C C   . TYR B 1 96  ? -53.557 34.981  23.012 1.00 94.78  ? 104 TYR B C   1 
ATOM   4382  O O   . TYR B 1 96  ? -52.572 35.371  22.397 1.00 111.81 ? 104 TYR B O   1 
ATOM   4383  C CB  . TYR B 1 96  ? -53.955 37.322  23.882 1.00 93.03  ? 104 TYR B CB  1 
ATOM   4384  C CG  . TYR B 1 96  ? -54.995 38.439  23.877 1.00 104.80 ? 104 TYR B CG  1 
ATOM   4385  C CD1 . TYR B 1 96  ? -55.294 39.193  22.732 1.00 93.07  ? 104 TYR B CD1 1 
ATOM   4386  C CD2 . TYR B 1 96  ? -55.701 38.712  25.039 1.00 95.19  ? 104 TYR B CD2 1 
ATOM   4387  C CE1 . TYR B 1 96  ? -56.262 40.180  22.752 1.00 89.89  ? 104 TYR B CE1 1 
ATOM   4388  C CE2 . TYR B 1 96  ? -56.685 39.685  25.056 1.00 114.30 ? 104 TYR B CE2 1 
ATOM   4389  C CZ  . TYR B 1 96  ? -56.964 40.429  23.926 1.00 106.73 ? 104 TYR B CZ  1 
ATOM   4390  O OH  . TYR B 1 96  ? -57.915 41.418  24.075 1.00 95.30  ? 104 TYR B OH  1 
ATOM   4391  N N   . LYS B 1 97  ? -53.794 33.702  23.359 1.00 85.77  ? 105 LYS B N   1 
ATOM   4392  C CA  . LYS B 1 97  ? -53.022 32.562  22.867 1.00 90.08  ? 105 LYS B CA  1 
ATOM   4393  C C   . LYS B 1 97  ? -51.575 32.808  23.276 1.00 84.57  ? 105 LYS B C   1 
ATOM   4394  O O   . LYS B 1 97  ? -50.650 32.700  22.487 1.00 127.42 ? 105 LYS B O   1 
ATOM   4395  C CB  . LYS B 1 97  ? -53.288 32.193  21.382 1.00 79.11  ? 105 LYS B CB  1 
ATOM   4396  C CG  . LYS B 1 97  ? -54.793 31.961  20.979 1.00 72.42  ? 105 LYS B CG  1 
ATOM   4397  C CD  . LYS B 1 97  ? -55.333 30.870  20.044 1.00 70.24  ? 105 LYS B CD  1 
ATOM   4398  C CE  . LYS B 1 97  ? -56.712 31.018  19.381 1.00 85.97  ? 105 LYS B CE  1 
ATOM   4399  N NZ  . LYS B 1 97  ? -56.917 31.527  18.000 1.00 72.86  ? 105 LYS B NZ  1 
ATOM   4400  N N   . LEU B 1 98  ? -51.373 33.166  24.534 1.00 91.69  ? 106 LEU B N   1 
ATOM   4401  C CA  . LEU B 1 98  ? -50.035 33.400  25.057 1.00 109.57 ? 106 LEU B CA  1 
ATOM   4402  C C   . LEU B 1 98  ? -49.632 32.219  25.948 1.00 112.63 ? 106 LEU B C   1 
ATOM   4403  O O   . LEU B 1 98  ? -50.385 31.767  26.831 1.00 91.30  ? 106 LEU B O   1 
ATOM   4404  C CB  . LEU B 1 98  ? -50.170 34.651  25.920 1.00 121.58 ? 106 LEU B CB  1 
ATOM   4405  C CG  . LEU B 1 98  ? -50.662 35.925  25.224 1.00 98.75  ? 106 LEU B CG  1 
ATOM   4406  C CD1 . LEU B 1 98  ? -50.656 37.115  26.129 1.00 82.11  ? 106 LEU B CD1 1 
ATOM   4407  C CD2 . LEU B 1 98  ? -49.865 36.221  23.996 1.00 86.88  ? 106 LEU B CD2 1 
ATOM   4408  N N   . ASP B 1 99  ? -48.388 31.772  25.756 1.00 81.72  ? 107 ASP B N   1 
ATOM   4409  C CA  . ASP B 1 99  ? -47.777 30.748  26.594 1.00 78.03  ? 107 ASP B CA  1 
ATOM   4410  C C   . ASP B 1 99  ? -47.436 31.333  27.975 1.00 74.62  ? 107 ASP B C   1 
ATOM   4411  O O   . ASP B 1 99  ? -46.725 32.343  28.082 1.00 111.37 ? 107 ASP B O   1 
ATOM   4412  C CB  . ASP B 1 99  ? -46.587 30.114  25.882 1.00 89.26  ? 107 ASP B CB  1 
ATOM   4413  C CG  . ASP B 1 99  ? -45.767 29.222  26.792 1.00 97.72  ? 107 ASP B CG  1 
ATOM   4414  O OD1 . ASP B 1 99  ? -46.335 28.302  27.408 1.00 123.08 ? 107 ASP B OD1 1 
ATOM   4415  O OD2 . ASP B 1 99  ? -44.570 29.408  26.849 1.00 107.29 ? 107 ASP B OD2 1 
ATOM   4416  N N   . PRO B 1 100 ? -47.933 30.773  29.096 1.00 59.97  ? 108 PRO B N   1 
ATOM   4417  C CA  . PRO B 1 100 ? -47.634 31.297  30.434 1.00 70.60  ? 108 PRO B CA  1 
ATOM   4418  C C   . PRO B 1 100 ? -46.157 31.329  30.794 1.00 77.88  ? 108 PRO B C   1 
ATOM   4419  O O   . PRO B 1 100 ? -45.770 32.011  31.752 1.00 83.58  ? 108 PRO B O   1 
ATOM   4420  C CB  . PRO B 1 100 ? -48.447 30.466  31.413 1.00 63.18  ? 108 PRO B CB  1 
ATOM   4421  C CG  . PRO B 1 100 ? -49.574 29.971  30.519 1.00 66.12  ? 108 PRO B CG  1 
ATOM   4422  C CD  . PRO B 1 100 ? -48.937 29.719  29.146 1.00 65.82  ? 108 PRO B CD  1 
ATOM   4423  N N   . GLN B 1 101 ? -45.338 30.620  30.005 1.00 66.39  ? 109 GLN B N   1 
ATOM   4424  C CA  . GLN B 1 101 ? -43.911 30.706  30.247 1.00 89.68  ? 109 GLN B CA  1 
ATOM   4425  C C   . GLN B 1 101 ? -43.315 31.872  29.472 1.00 87.15  ? 109 GLN B C   1 
ATOM   4426  O O   . GLN B 1 101 ? -42.167 32.223  29.658 1.00 116.69 ? 109 GLN B O   1 
ATOM   4427  C CB  . GLN B 1 101 ? -43.131 29.410  30.170 1.00 103.08 ? 109 GLN B CB  1 
ATOM   4428  C CG  . GLN B 1 101 ? -42.853 28.931  31.584 1.00 101.88 ? 109 GLN B CG  1 
ATOM   4429  C CD  . GLN B 1 101 ? -42.890 27.433  31.590 1.00 138.68 ? 109 GLN B CD  1 
ATOM   4430  O OE1 . GLN B 1 101 ? -43.240 26.802  30.582 1.00 141.57 ? 109 GLN B OE1 1 
ATOM   4431  N NE2 . GLN B 1 101 ? -42.532 26.865  32.730 1.00 147.34 ? 109 GLN B NE2 1 
ATOM   4432  N N   . CYS B 1 102 ? -44.101 32.499  28.617 1.00 77.47  ? 110 CYS B N   1 
ATOM   4433  C CA  . CYS B 1 102 ? -43.569 33.647  27.905 1.00 94.98  ? 110 CYS B CA  1 
ATOM   4434  C C   . CYS B 1 102 ? -44.299 34.936  28.246 1.00 103.04 ? 110 CYS B C   1 
ATOM   4435  O O   . CYS B 1 102 ? -43.815 36.028  27.865 1.00 100.04 ? 110 CYS B O   1 
ATOM   4436  C CB  . CYS B 1 102 ? -43.809 33.537  26.417 1.00 95.90  ? 110 CYS B CB  1 
ATOM   4437  S SG  . CYS B 1 102 ? -42.923 32.133  25.727 1.00 97.30  ? 110 CYS B SG  1 
ATOM   4438  N N   . TRP B 1 103 ? -45.463 34.789  28.907 1.00 71.59  ? 111 TRP B N   1 
ATOM   4439  C CA  . TRP B 1 103 ? -46.251 35.949  29.280 1.00 60.85  ? 111 TRP B CA  1 
ATOM   4440  C C   . TRP B 1 103 ? -46.807 35.809  30.688 1.00 64.73  ? 111 TRP B C   1 
ATOM   4441  O O   . TRP B 1 103 ? -47.179 34.712  31.107 1.00 95.68  ? 111 TRP B O   1 
ATOM   4442  C CB  . TRP B 1 103 ? -47.381 36.151  28.265 1.00 50.77  ? 111 TRP B CB  1 
ATOM   4443  C CG  . TRP B 1 103 ? -46.929 36.734  26.954 1.00 51.37  ? 111 TRP B CG  1 
ATOM   4444  C CD1 . TRP B 1 103 ? -46.698 36.012  25.837 1.00 38.94  ? 111 TRP B CD1 1 
ATOM   4445  C CD2 . TRP B 1 103 ? -46.732 38.132  26.606 1.00 75.40  ? 111 TRP B CD2 1 
ATOM   4446  N NE1 . TRP B 1 103 ? -46.340 36.857  24.822 1.00 53.43  ? 111 TRP B NE1 1 
ATOM   4447  C CE2 . TRP B 1 103 ? -46.336 38.158  25.246 1.00 74.97  ? 111 TRP B CE2 1 
ATOM   4448  C CE3 . TRP B 1 103 ? -46.864 39.356  27.287 1.00 54.55  ? 111 TRP B CE3 1 
ATOM   4449  C CZ2 . TRP B 1 103 ? -46.037 39.343  24.556 1.00 65.67  ? 111 TRP B CZ2 1 
ATOM   4450  C CZ3 . TRP B 1 103 ? -46.583 40.520  26.604 1.00 68.80  ? 111 TRP B CZ3 1 
ATOM   4451  C CH2 . TRP B 1 103 ? -46.160 40.520  25.263 1.00 69.76  ? 111 TRP B CH2 1 
ATOM   4452  N N   . GLY B 1 104 ? -46.894 36.934  31.396 1.00 62.14  ? 112 GLY B N   1 
ATOM   4453  C CA  . GLY B 1 104 ? -47.787 37.037  32.543 1.00 79.58  ? 112 GLY B CA  1 
ATOM   4454  C C   . GLY B 1 104 ? -48.820 38.146  32.330 1.00 83.00  ? 112 GLY B C   1 
ATOM   4455  O O   . GLY B 1 104 ? -48.724 38.934  31.390 1.00 90.82  ? 112 GLY B O   1 
ATOM   4456  N N   . VAL B 1 105 ? -49.809 38.238  33.212 1.00 72.64  ? 113 VAL B N   1 
ATOM   4457  C CA  . VAL B 1 105 ? -50.770 39.322  33.082 1.00 77.60  ? 113 VAL B CA  1 
ATOM   4458  C C   . VAL B 1 105 ? -51.248 39.749  34.472 1.00 89.27  ? 113 VAL B C   1 
ATOM   4459  O O   . VAL B 1 105 ? -51.578 38.910  35.299 1.00 111.01 ? 113 VAL B O   1 
ATOM   4460  C CB  . VAL B 1 105 ? -51.963 38.954  32.185 1.00 79.08  ? 113 VAL B CB  1 
ATOM   4461  C CG1 . VAL B 1 105 ? -52.744 37.805  32.794 1.00 87.34  ? 113 VAL B CG1 1 
ATOM   4462  C CG2 . VAL B 1 105 ? -52.884 40.150  31.996 1.00 77.07  ? 113 VAL B CG2 1 
ATOM   4463  N N   . ASN B 1 106 ? -51.352 41.061  34.696 1.00 86.98  ? 114 ASN B N   1 
ATOM   4464  C CA  . ASN B 1 106 ? -51.963 41.565  35.899 1.00 92.88  ? 114 ASN B CA  1 
ATOM   4465  C C   . ASN B 1 106 ? -53.362 42.083  35.544 1.00 111.10 ? 114 ASN B C   1 
ATOM   4466  O O   . ASN B 1 106 ? -53.530 42.843  34.586 1.00 111.16 ? 114 ASN B O   1 
ATOM   4467  C CB  . ASN B 1 106 ? -51.005 42.633  36.381 1.00 88.71  ? 114 ASN B CB  1 
ATOM   4468  C CG  . ASN B 1 106 ? -51.479 43.431  37.572 1.00 100.07 ? 114 ASN B CG  1 
ATOM   4469  O OD1 . ASN B 1 106 ? -52.650 43.834  37.675 1.00 93.08  ? 114 ASN B OD1 1 
ATOM   4470  N ND2 . ASN B 1 106 ? -50.544 43.706  38.450 1.00 84.76  ? 114 ASN B ND2 1 
ATOM   4471  N N   . VAL B 1 107 ? -54.361 41.694  36.347 1.00 97.18  ? 115 VAL B N   1 
ATOM   4472  C CA  . VAL B 1 107 ? -55.747 42.011  36.023 1.00 88.54  ? 115 VAL B CA  1 
ATOM   4473  C C   . VAL B 1 107 ? -56.340 43.006  37.028 1.00 96.88  ? 115 VAL B C   1 
ATOM   4474  O O   . VAL B 1 107 ? -57.554 43.123  37.147 1.00 94.26  ? 115 VAL B O   1 
ATOM   4475  C CB  . VAL B 1 107 ? -56.601 40.724  35.983 1.00 87.10  ? 115 VAL B CB  1 
ATOM   4476  C CG1 . VAL B 1 107 ? -56.269 39.852  34.788 1.00 100.16 ? 115 VAL B CG1 1 
ATOM   4477  C CG2 . VAL B 1 107 ? -56.442 39.900  37.248 1.00 103.97 ? 115 VAL B CG2 1 
ATOM   4478  N N   . GLN B 1 108 ? -55.512 43.725  37.790 1.00 97.29  ? 116 GLN B N   1 
ATOM   4479  C CA  . GLN B 1 108 ? -56.068 44.594  38.819 1.00 93.97  ? 116 GLN B CA  1 
ATOM   4480  C C   . GLN B 1 108 ? -56.305 46.034  38.370 1.00 102.98 ? 116 GLN B C   1 
ATOM   4481  O O   . GLN B 1 108 ? -57.046 46.763  39.033 1.00 138.67 ? 116 GLN B O   1 
ATOM   4482  C CB  . GLN B 1 108 ? -55.202 44.651  40.067 1.00 79.76  ? 116 GLN B CB  1 
ATOM   4483  C CG  . GLN B 1 108 ? -55.378 43.418  40.923 1.00 75.61  ? 116 GLN B CG  1 
ATOM   4484  C CD  . GLN B 1 108 ? -54.493 43.461  42.133 1.00 97.74  ? 116 GLN B CD  1 
ATOM   4485  O OE1 . GLN B 1 108 ? -54.495 44.438  42.929 1.00 107.13 ? 116 GLN B OE1 1 
ATOM   4486  N NE2 . GLN B 1 108 ? -53.713 42.371  42.169 1.00 55.58  ? 116 GLN B NE2 1 
ATOM   4487  N N   . PRO B 1 109 ? -55.692 46.530  37.275 1.00 81.83  ? 117 PRO B N   1 
ATOM   4488  C CA  . PRO B 1 109 ? -55.908 47.921  36.879 1.00 78.32  ? 117 PRO B CA  1 
ATOM   4489  C C   . PRO B 1 109 ? -57.387 48.290  36.938 1.00 89.46  ? 117 PRO B C   1 
ATOM   4490  O O   . PRO B 1 109 ? -58.252 47.590  36.403 1.00 108.25 ? 117 PRO B O   1 
ATOM   4491  C CB  . PRO B 1 109 ? -55.369 47.913  35.451 1.00 76.62  ? 117 PRO B CB  1 
ATOM   4492  C CG  . PRO B 1 109 ? -54.223 46.922  35.517 1.00 88.98  ? 117 PRO B CG  1 
ATOM   4493  C CD  . PRO B 1 109 ? -54.819 45.800  36.341 1.00 90.39  ? 117 PRO B CD  1 
ATOM   4494  N N   . TYR B 1 110 ? -57.669 49.426  37.581 1.00 81.16  ? 118 TYR B N   1 
ATOM   4495  C CA  . TYR B 1 110 ? -59.026 49.909  37.760 1.00 85.13  ? 118 TYR B CA  1 
ATOM   4496  C C   . TYR B 1 110 ? -59.686 50.273  36.427 1.00 104.58 ? 118 TYR B C   1 
ATOM   4497  O O   . TYR B 1 110 ? -60.910 50.179  36.300 1.00 100.58 ? 118 TYR B O   1 
ATOM   4498  C CB  . TYR B 1 110 ? -58.842 51.165  38.603 1.00 66.20  ? 118 TYR B CB  1 
ATOM   4499  C CG  . TYR B 1 110 ? -58.563 50.827  40.053 1.00 75.51  ? 118 TYR B CG  1 
ATOM   4500  C CD1 . TYR B 1 110 ? -59.252 49.784  40.688 1.00 69.18  ? 118 TYR B CD1 1 
ATOM   4501  C CD2 . TYR B 1 110 ? -57.637 51.568  40.803 1.00 72.68  ? 118 TYR B CD2 1 
ATOM   4502  C CE1 . TYR B 1 110 ? -59.036 49.522  42.036 1.00 67.66  ? 118 TYR B CE1 1 
ATOM   4503  C CE2 . TYR B 1 110 ? -57.413 51.293  42.142 1.00 79.62  ? 118 TYR B CE2 1 
ATOM   4504  C CZ  . TYR B 1 110 ? -58.100 50.258  42.741 1.00 85.80  ? 118 TYR B CZ  1 
ATOM   4505  O OH  . TYR B 1 110 ? -57.829 49.995  44.036 1.00 125.33 ? 118 TYR B OH  1 
ATOM   4506  N N   . SER B 1 111 ? -58.876 50.734  35.468 1.00 100.12 ? 119 SER B N   1 
ATOM   4507  C CA  . SER B 1 111 ? -59.391 51.108  34.166 1.00 87.40  ? 119 SER B CA  1 
ATOM   4508  C C   . SER B 1 111 ? -58.225 51.144  33.186 1.00 81.49  ? 119 SER B C   1 
ATOM   4509  O O   . SER B 1 111 ? -57.150 50.652  33.512 1.00 81.31  ? 119 SER B O   1 
ATOM   4510  C CB  . SER B 1 111 ? -60.129 52.422  34.231 1.00 94.77  ? 119 SER B CB  1 
ATOM   4511  O OG  . SER B 1 111 ? -61.186 52.375  33.282 1.00 88.13  ? 119 SER B OG  1 
ATOM   4512  N N   . GLY B 1 112 ? -58.444 51.715  32.001 1.00 66.81  ? 120 GLY B N   1 
ATOM   4513  C CA  . GLY B 1 112 ? -57.404 51.729  30.995 1.00 81.62  ? 120 GLY B CA  1 
ATOM   4514  C C   . GLY B 1 112 ? -56.284 52.687  31.389 1.00 98.70  ? 120 GLY B C   1 
ATOM   4515  O O   . GLY B 1 112 ? -55.100 52.318  31.421 1.00 106.18 ? 120 GLY B O   1 
ATOM   4516  N N   . SER B 1 113 ? -56.641 53.953  31.642 1.00 90.29  ? 121 SER B N   1 
ATOM   4517  C CA  . SER B 1 113 ? -55.637 54.933  32.002 1.00 68.71  ? 121 SER B CA  1 
ATOM   4518  C C   . SER B 1 113 ? -54.815 54.420  33.185 1.00 73.48  ? 121 SER B C   1 
ATOM   4519  O O   . SER B 1 113 ? -53.594 54.577  33.183 1.00 47.79  ? 121 SER B O   1 
ATOM   4520  C CB  . SER B 1 113 ? -56.244 56.290  32.289 1.00 71.02  ? 121 SER B CB  1 
ATOM   4521  O OG  . SER B 1 113 ? -57.181 56.664  31.308 1.00 66.44  ? 121 SER B OG  1 
ATOM   4522  N N   . PRO B 1 114 ? -55.420 53.899  34.294 1.00 83.35  ? 122 PRO B N   1 
ATOM   4523  C CA  . PRO B 1 114 ? -54.608 53.351  35.390 1.00 92.68  ? 122 PRO B CA  1 
ATOM   4524  C C   . PRO B 1 114 ? -53.600 52.288  34.951 1.00 99.70  ? 122 PRO B C   1 
ATOM   4525  O O   . PRO B 1 114 ? -52.469 52.258  35.420 1.00 79.06  ? 122 PRO B O   1 
ATOM   4526  C CB  . PRO B 1 114 ? -55.621 52.811  36.329 1.00 69.65  ? 122 PRO B CB  1 
ATOM   4527  C CG  . PRO B 1 114 ? -56.785 53.741  36.055 1.00 70.66  ? 122 PRO B CG  1 
ATOM   4528  C CD  . PRO B 1 114 ? -56.858 53.893  34.575 1.00 71.51  ? 122 PRO B CD  1 
ATOM   4529  N N   . ALA B 1 115 ? -53.991 51.454  33.991 1.00 88.10  ? 123 ALA B N   1 
ATOM   4530  C CA  . ALA B 1 115 ? -53.083 50.426  33.527 1.00 73.50  ? 123 ALA B CA  1 
ATOM   4531  C C   . ALA B 1 115 ? -51.816 51.032  32.906 1.00 68.10  ? 123 ALA B C   1 
ATOM   4532  O O   . ALA B 1 115 ? -50.692 50.635  33.247 1.00 50.72  ? 123 ALA B O   1 
ATOM   4533  C CB  . ALA B 1 115 ? -53.829 49.468  32.623 1.00 47.74  ? 123 ALA B CB  1 
ATOM   4534  N N   . ASN B 1 116 ? -52.006 52.027  32.033 1.00 62.47  ? 124 ASN B N   1 
ATOM   4535  C CA  . ASN B 1 116 ? -50.872 52.594  31.317 1.00 80.74  ? 124 ASN B CA  1 
ATOM   4536  C C   . ASN B 1 116 ? -49.977 53.283  32.351 1.00 88.68  ? 124 ASN B C   1 
ATOM   4537  O O   . ASN B 1 116 ? -48.743 53.134  32.343 1.00 95.58  ? 124 ASN B O   1 
ATOM   4538  C CB  . ASN B 1 116 ? -51.300 53.615  30.260 1.00 78.22  ? 124 ASN B CB  1 
ATOM   4539  C CG  . ASN B 1 116 ? -52.014 53.038  29.080 1.00 95.96  ? 124 ASN B CG  1 
ATOM   4540  O OD1 . ASN B 1 116 ? -51.966 51.821  28.888 1.00 121.06 ? 124 ASN B OD1 1 
ATOM   4541  N ND2 . ASN B 1 116 ? -52.608 53.903  28.269 1.00 114.93 ? 124 ASN B ND2 1 
ATOM   4542  N N   . PHE B 1 117 ? -50.619 54.048  33.248 1.00 61.26  ? 125 PHE B N   1 
ATOM   4543  C CA  . PHE B 1 117 ? -49.860 54.846  34.190 1.00 63.80  ? 125 PHE B CA  1 
ATOM   4544  C C   . PHE B 1 117 ? -48.981 53.890  34.995 1.00 69.33  ? 125 PHE B C   1 
ATOM   4545  O O   . PHE B 1 117 ? -47.831 54.227  35.320 1.00 58.58  ? 125 PHE B O   1 
ATOM   4546  C CB  . PHE B 1 117 ? -50.782 55.744  35.040 1.00 60.44  ? 125 PHE B CB  1 
ATOM   4547  C CG  . PHE B 1 117 ? -49.962 56.767  35.810 1.00 53.50  ? 125 PHE B CG  1 
ATOM   4548  C CD1 . PHE B 1 117 ? -49.624 57.988  35.210 1.00 53.33  ? 125 PHE B CD1 1 
ATOM   4549  C CD2 . PHE B 1 117 ? -49.411 56.465  37.066 1.00 54.69  ? 125 PHE B CD2 1 
ATOM   4550  C CE1 . PHE B 1 117 ? -48.780 58.902  35.858 1.00 49.50  ? 125 PHE B CE1 1 
ATOM   4551  C CE2 . PHE B 1 117 ? -48.609 57.404  37.737 1.00 52.75  ? 125 PHE B CE2 1 
ATOM   4552  C CZ  . PHE B 1 117 ? -48.300 58.614  37.130 1.00 51.13  ? 125 PHE B CZ  1 
ATOM   4553  N N   . ALA B 1 118 ? -49.558 52.706  35.299 1.00 60.80  ? 126 ALA B N   1 
ATOM   4554  C CA  . ALA B 1 118 ? -48.855 51.696  36.080 1.00 75.33  ? 126 ALA B CA  1 
ATOM   4555  C C   . ALA B 1 118 ? -47.609 51.204  35.328 1.00 82.94  ? 126 ALA B C   1 
ATOM   4556  O O   . ALA B 1 118 ? -46.515 51.063  35.887 1.00 52.26  ? 126 ALA B O   1 
ATOM   4557  C CB  . ALA B 1 118 ? -49.786 50.558  36.389 1.00 50.99  ? 126 ALA B CB  1 
ATOM   4558  N N   . VAL B 1 119 ? -47.775 50.945  34.030 1.00 72.11  ? 127 VAL B N   1 
ATOM   4559  C CA  . VAL B 1 119 ? -46.632 50.484  33.263 1.00 84.33  ? 127 VAL B CA  1 
ATOM   4560  C C   . VAL B 1 119 ? -45.526 51.550  33.226 1.00 83.84  ? 127 VAL B C   1 
ATOM   4561  O O   . VAL B 1 119 ? -44.341 51.180  33.314 1.00 58.63  ? 127 VAL B O   1 
ATOM   4562  C CB  . VAL B 1 119 ? -47.044 49.984  31.864 1.00 89.70  ? 127 VAL B CB  1 
ATOM   4563  C CG1 . VAL B 1 119 ? -45.852 49.657  30.962 1.00 77.63  ? 127 VAL B CG1 1 
ATOM   4564  C CG2 . VAL B 1 119 ? -47.944 48.764  31.977 1.00 103.21 ? 127 VAL B CG2 1 
ATOM   4565  N N   . TYR B 1 120 ? -45.906 52.839  33.071 1.00 66.76  ? 128 TYR B N   1 
ATOM   4566  C CA  . TYR B 1 120 ? -44.904 53.895  33.003 1.00 75.58  ? 128 TYR B CA  1 
ATOM   4567  C C   . TYR B 1 120 ? -44.179 54.014  34.347 1.00 91.53  ? 128 TYR B C   1 
ATOM   4568  O O   . TYR B 1 120 ? -42.945 54.172  34.410 1.00 79.92  ? 128 TYR B O   1 
ATOM   4569  C CB  . TYR B 1 120 ? -45.547 55.236  32.684 1.00 67.01  ? 128 TYR B CB  1 
ATOM   4570  C CG  . TYR B 1 120 ? -46.481 55.252  31.480 1.00 73.07  ? 128 TYR B CG  1 
ATOM   4571  C CD1 . TYR B 1 120 ? -46.127 54.654  30.277 1.00 76.26  ? 128 TYR B CD1 1 
ATOM   4572  C CD2 . TYR B 1 120 ? -47.696 55.931  31.525 1.00 87.27  ? 128 TYR B CD2 1 
ATOM   4573  C CE1 . TYR B 1 120 ? -46.949 54.704  29.159 1.00 59.08  ? 128 TYR B CE1 1 
ATOM   4574  C CE2 . TYR B 1 120 ? -48.532 55.993  30.423 1.00 89.49  ? 128 TYR B CE2 1 
ATOM   4575  C CZ  . TYR B 1 120 ? -48.172 55.345  29.254 1.00 82.24  ? 128 TYR B CZ  1 
ATOM   4576  O OH  . TYR B 1 120 ? -49.038 55.412  28.208 1.00 113.61 ? 128 TYR B OH  1 
ATOM   4577  N N   . THR B 1 121 ? -44.965 53.856  35.422 1.00 87.19  ? 129 THR B N   1 
ATOM   4578  C CA  . THR B 1 121 ? -44.421 53.857  36.772 1.00 87.38  ? 129 THR B CA  1 
ATOM   4579  C C   . THR B 1 121 ? -43.411 52.731  36.963 1.00 73.50  ? 129 THR B C   1 
ATOM   4580  O O   . THR B 1 121 ? -42.354 52.990  37.532 1.00 55.21  ? 129 THR B O   1 
ATOM   4581  C CB  . THR B 1 121 ? -45.482 53.815  37.868 1.00 67.72  ? 129 THR B CB  1 
ATOM   4582  O OG1 . THR B 1 121 ? -46.300 54.973  37.731 1.00 75.22  ? 129 THR B OG1 1 
ATOM   4583  C CG2 . THR B 1 121 ? -44.791 53.937  39.208 1.00 42.47  ? 129 THR B CG2 1 
ATOM   4584  N N   . ALA B 1 122 ? -43.745 51.527  36.467 1.00 62.04  ? 130 ALA B N   1 
ATOM   4585  C CA  . ALA B 1 122 ? -42.905 50.337  36.663 1.00 74.44  ? 130 ALA B CA  1 
ATOM   4586  C C   . ALA B 1 122 ? -41.642 50.380  35.808 1.00 89.57  ? 130 ALA B C   1 
ATOM   4587  O O   . ALA B 1 122 ? -40.576 49.960  36.248 1.00 86.19  ? 130 ALA B O   1 
ATOM   4588  C CB  . ALA B 1 122 ? -43.618 49.051  36.336 1.00 59.42  ? 130 ALA B CB  1 
ATOM   4589  N N   . LEU B 1 123 ? -41.755 50.889  34.571 1.00 76.07  ? 131 LEU B N   1 
ATOM   4590  C CA  . LEU B 1 123 ? -40.673 50.707  33.631 1.00 65.62  ? 131 LEU B CA  1 
ATOM   4591  C C   . LEU B 1 123 ? -39.947 52.010  33.351 1.00 60.52  ? 131 LEU B C   1 
ATOM   4592  O O   . LEU B 1 123 ? -38.834 51.959  32.840 1.00 62.31  ? 131 LEU B O   1 
ATOM   4593  C CB  . LEU B 1 123 ? -41.220 50.074  32.358 1.00 54.69  ? 131 LEU B CB  1 
ATOM   4594  C CG  . LEU B 1 123 ? -41.863 48.709  32.586 1.00 73.33  ? 131 LEU B CG  1 
ATOM   4595  C CD1 . LEU B 1 123 ? -42.275 48.081  31.239 1.00 76.16  ? 131 LEU B CD1 1 
ATOM   4596  C CD2 . LEU B 1 123 ? -40.912 47.810  33.409 1.00 58.96  ? 131 LEU B CD2 1 
ATOM   4597  N N   . VAL B 1 124 ? -40.589 53.155  33.583 1.00 63.30  ? 132 VAL B N   1 
ATOM   4598  C CA  . VAL B 1 124 ? -39.998 54.352  33.016 1.00 70.62  ? 132 VAL B CA  1 
ATOM   4599  C C   . VAL B 1 124 ? -39.355 55.162  34.103 1.00 87.37  ? 132 VAL B C   1 
ATOM   4600  O O   . VAL B 1 124 ? -38.320 55.781  33.818 1.00 96.58  ? 132 VAL B O   1 
ATOM   4601  C CB  . VAL B 1 124 ? -40.935 55.179  32.150 1.00 67.92  ? 132 VAL B CB  1 
ATOM   4602  C CG1 . VAL B 1 124 ? -40.257 56.474  31.692 1.00 77.87  ? 132 VAL B CG1 1 
ATOM   4603  C CG2 . VAL B 1 124 ? -41.304 54.281  30.962 1.00 58.30  ? 132 VAL B CG2 1 
ATOM   4604  N N   . GLU B 1 125 ? -39.994 55.165  35.291 1.00 84.97  ? 133 GLU B N   1 
ATOM   4605  C CA  . GLU B 1 125 ? -39.445 55.902  36.439 1.00 68.27  ? 133 GLU B CA  1 
ATOM   4606  C C   . GLU B 1 125 ? -39.510 57.398  36.102 1.00 69.79  ? 133 GLU B C   1 
ATOM   4607  O O   . GLU B 1 125 ? -39.491 57.812  34.925 1.00 60.88  ? 133 GLU B O   1 
ATOM   4608  C CB  . GLU B 1 125 ? -38.055 55.486  36.957 1.00 45.97  ? 133 GLU B CB  1 
ATOM   4609  C CG  . GLU B 1 125 ? -37.899 53.965  36.980 1.00 55.28  ? 133 GLU B CG  1 
ATOM   4610  C CD  . GLU B 1 125 ? -36.952 53.354  37.979 1.00 64.81  ? 133 GLU B CD  1 
ATOM   4611  O OE1 . GLU B 1 125 ? -37.199 53.733  39.111 1.00 71.93  ? 133 GLU B OE1 1 
ATOM   4612  O OE2 . GLU B 1 125 ? -36.063 52.504  37.739 1.00 84.07  ? 133 GLU B OE2 1 
ATOM   4613  N N   . PRO B 1 126 ? -39.680 58.244  37.144 1.00 56.65  ? 134 PRO B N   1 
ATOM   4614  C CA  . PRO B 1 126 ? -40.102 59.636  36.966 1.00 54.44  ? 134 PRO B CA  1 
ATOM   4615  C C   . PRO B 1 126 ? -39.190 60.407  36.021 1.00 54.78  ? 134 PRO B C   1 
ATOM   4616  O O   . PRO B 1 126 ? -38.000 60.251  36.056 1.00 63.78  ? 134 PRO B O   1 
ATOM   4617  C CB  . PRO B 1 126 ? -39.935 60.072  38.389 1.00 41.84  ? 134 PRO B CB  1 
ATOM   4618  C CG  . PRO B 1 126 ? -40.482 58.897  39.115 1.00 42.75  ? 134 PRO B CG  1 
ATOM   4619  C CD  . PRO B 1 126 ? -39.501 57.888  38.552 1.00 51.70  ? 134 PRO B CD  1 
ATOM   4620  N N   . HIS B 1 127 ? -39.766 61.212  35.158 1.00 58.37  ? 135 HIS B N   1 
ATOM   4621  C CA  . HIS B 1 127 ? -39.063 62.036  34.192 1.00 54.47  ? 135 HIS B CA  1 
ATOM   4622  C C   . HIS B 1 127 ? -38.506 61.201  33.023 1.00 66.74  ? 135 HIS B C   1 
ATOM   4623  O O   . HIS B 1 127 ? -37.864 61.774  32.107 1.00 77.16  ? 135 HIS B O   1 
ATOM   4624  C CB  . HIS B 1 127 ? -37.983 62.890  34.860 1.00 58.55  ? 135 HIS B CB  1 
ATOM   4625  C CG  . HIS B 1 127 ? -38.392 63.718  35.996 1.00 77.98  ? 135 HIS B CG  1 
ATOM   4626  N ND1 . HIS B 1 127 ? -38.987 64.930  35.729 1.00 104.46 ? 135 HIS B ND1 1 
ATOM   4627  C CD2 . HIS B 1 127 ? -38.258 63.617  37.342 1.00 64.04  ? 135 HIS B CD2 1 
ATOM   4628  C CE1 . HIS B 1 127 ? -39.230 65.546  36.899 1.00 116.14 ? 135 HIS B CE1 1 
ATOM   4629  N NE2 . HIS B 1 127 ? -38.767 64.769  37.900 1.00 86.38  ? 135 HIS B NE2 1 
ATOM   4630  N N   . GLY B 1 128 ? -38.737 59.865  33.048 1.00 51.51  ? 136 GLY B N   1 
ATOM   4631  C CA  . GLY B 1 128 ? -38.283 59.030  31.942 1.00 57.13  ? 136 GLY B CA  1 
ATOM   4632  C C   . GLY B 1 128 ? -39.000 59.413  30.650 1.00 61.21  ? 136 GLY B C   1 
ATOM   4633  O O   . GLY B 1 128 ? -40.113 59.972  30.688 1.00 94.68  ? 136 GLY B O   1 
ATOM   4634  N N   . ARG B 1 129 ? -38.328 59.195  29.517 1.00 52.82  ? 137 ARG B N   1 
ATOM   4635  C CA  . ARG B 1 129 ? -38.911 59.692  28.281 1.00 62.79  ? 137 ARG B CA  1 
ATOM   4636  C C   . ARG B 1 129 ? -39.852 58.676  27.637 1.00 61.99  ? 137 ARG B C   1 
ATOM   4637  O O   . ARG B 1 129 ? -39.490 57.513  27.431 1.00 47.33  ? 137 ARG B O   1 
ATOM   4638  C CB  . ARG B 1 129 ? -37.819 60.201  27.341 1.00 70.69  ? 137 ARG B CB  1 
ATOM   4639  C CG  . ARG B 1 129 ? -37.333 61.513  27.931 1.00 62.89  ? 137 ARG B CG  1 
ATOM   4640  C CD  . ARG B 1 129 ? -35.935 61.887  27.578 1.00 55.93  ? 137 ARG B CD  1 
ATOM   4641  N NE  . ARG B 1 129 ? -36.041 63.108  26.767 1.00 34.38  ? 137 ARG B NE  1 
ATOM   4642  C CZ  . ARG B 1 129 ? -35.189 64.113  27.066 1.00 49.11  ? 137 ARG B CZ  1 
ATOM   4643  N NH1 . ARG B 1 129 ? -34.566 64.742  26.055 1.00 57.43  ? 137 ARG B NH1 1 
ATOM   4644  N NH2 . ARG B 1 129 ? -34.809 64.386  28.333 1.00 35.51  ? 137 ARG B NH2 1 
ATOM   4645  N N   . ILE B 1 130 ? -41.041 59.160  27.248 1.00 64.17  ? 138 ILE B N   1 
ATOM   4646  C CA  . ILE B 1 130 ? -42.002 58.304  26.574 1.00 58.47  ? 138 ILE B CA  1 
ATOM   4647  C C   . ILE B 1 130 ? -42.359 58.921  25.224 1.00 60.93  ? 138 ILE B C   1 
ATOM   4648  O O   . ILE B 1 130 ? -42.438 60.145  25.116 1.00 73.56  ? 138 ILE B O   1 
ATOM   4649  C CB  . ILE B 1 130 ? -43.223 58.170  27.484 1.00 67.16  ? 138 ILE B CB  1 
ATOM   4650  C CG1 . ILE B 1 130 ? -42.865 57.452  28.790 1.00 77.22  ? 138 ILE B CG1 1 
ATOM   4651  C CG2 . ILE B 1 130 ? -44.415 57.558  26.746 1.00 79.69  ? 138 ILE B CG2 1 
ATOM   4652  C CD1 . ILE B 1 130 ? -44.012 57.460  29.795 1.00 106.05 ? 138 ILE B CD1 1 
ATOM   4653  N N   . MET B 1 131 ? -42.539 58.077  24.192 1.00 63.62  ? 139 MET B N   1 
ATOM   4654  C CA  . MET B 1 131 ? -43.037 58.528  22.899 1.00 65.77  ? 139 MET B CA  1 
ATOM   4655  C C   . MET B 1 131 ? -44.295 57.760  22.540 1.00 71.34  ? 139 MET B C   1 
ATOM   4656  O O   . MET B 1 131 ? -44.305 56.530  22.581 1.00 79.43  ? 139 MET B O   1 
ATOM   4657  C CB  . MET B 1 131 ? -42.031 58.401  21.747 1.00 56.77  ? 139 MET B CB  1 
ATOM   4658  C CG  . MET B 1 131 ? -40.864 59.390  21.844 1.00 71.16  ? 139 MET B CG  1 
ATOM   4659  S SD  . MET B 1 131 ? -39.684 59.255  20.483 1.00 101.53 ? 139 MET B SD  1 
ATOM   4660  C CE  . MET B 1 131 ? -40.552 60.346  19.342 1.00 107.37 ? 139 MET B CE  1 
ATOM   4661  N N   . GLY B 1 132 ? -45.341 58.504  22.167 1.00 67.49  ? 140 GLY B N   1 
ATOM   4662  C CA  . GLY B 1 132 ? -46.497 57.894  21.524 1.00 83.53  ? 140 GLY B CA  1 
ATOM   4663  C C   . GLY B 1 132 ? -47.036 58.760  20.397 1.00 85.79  ? 140 GLY B C   1 
ATOM   4664  O O   . GLY B 1 132 ? -46.543 59.864  20.151 1.00 78.47  ? 140 GLY B O   1 
ATOM   4665  N N   . LEU B 1 133 ? -48.100 58.272  19.761 1.00 82.79  ? 141 LEU B N   1 
ATOM   4666  C CA  . LEU B 1 133 ? -48.724 59.058  18.701 1.00 84.59  ? 141 LEU B CA  1 
ATOM   4667  C C   . LEU B 1 133 ? -49.232 60.401  19.241 1.00 80.51  ? 141 LEU B C   1 
ATOM   4668  O O   . LEU B 1 133 ? -49.952 60.394  20.204 1.00 75.78  ? 141 LEU B O   1 
ATOM   4669  C CB  . LEU B 1 133 ? -49.885 58.237  18.146 1.00 86.06  ? 141 LEU B CB  1 
ATOM   4670  C CG  . LEU B 1 133 ? -50.609 58.864  16.948 1.00 66.68  ? 141 LEU B CG  1 
ATOM   4671  C CD1 . LEU B 1 133 ? -49.651 59.112  15.786 1.00 62.86  ? 141 LEU B CD1 1 
ATOM   4672  C CD2 . LEU B 1 133 ? -51.751 58.115  16.401 1.00 50.93  ? 141 LEU B CD2 1 
ATOM   4673  N N   . ASP B 1 134 ? -48.934 61.536  18.592 1.00 99.54  ? 142 ASP B N   1 
ATOM   4674  C CA  . ASP B 1 134 ? -49.398 62.836  19.068 1.00 83.78  ? 142 ASP B CA  1 
ATOM   4675  C C   . ASP B 1 134 ? -50.909 62.782  19.192 1.00 74.17  ? 142 ASP B C   1 
ATOM   4676  O O   . ASP B 1 134 ? -51.558 62.152  18.365 1.00 86.39  ? 142 ASP B O   1 
ATOM   4677  C CB  . ASP B 1 134 ? -49.053 63.993  18.128 1.00 94.46  ? 142 ASP B CB  1 
ATOM   4678  C CG  . ASP B 1 134 ? -49.067 65.375  18.797 1.00 103.89 ? 142 ASP B CG  1 
ATOM   4679  O OD1 . ASP B 1 134 ? -49.233 65.391  20.019 1.00 130.70 ? 142 ASP B OD1 1 
ATOM   4680  O OD2 . ASP B 1 134 ? -48.963 66.439  18.139 1.00 85.48  ? 142 ASP B OD2 1 
ATOM   4681  N N   . LEU B 1 135 ? -51.463 63.447  20.200 1.00 71.63  ? 143 LEU B N   1 
ATOM   4682  C CA  . LEU B 1 135 ? -52.904 63.452  20.406 1.00 80.44  ? 143 LEU B CA  1 
ATOM   4683  C C   . LEU B 1 135 ? -53.707 63.878  19.164 1.00 80.85  ? 143 LEU B C   1 
ATOM   4684  O O   . LEU B 1 135 ? -54.580 63.141  18.715 1.00 83.09  ? 143 LEU B O   1 
ATOM   4685  C CB  . LEU B 1 135 ? -53.237 64.328  21.606 1.00 70.87  ? 143 LEU B CB  1 
ATOM   4686  C CG  . LEU B 1 135 ? -54.661 64.090  22.103 1.00 83.57  ? 143 LEU B CG  1 
ATOM   4687  C CD1 . LEU B 1 135 ? -54.909 62.656  22.495 1.00 73.53  ? 143 LEU B CD1 1 
ATOM   4688  C CD2 . LEU B 1 135 ? -54.961 64.952  23.263 1.00 97.37  ? 143 LEU B CD2 1 
ATOM   4689  N N   . PRO B 1 136 ? -53.468 65.059  18.553 1.00 77.86  ? 144 PRO B N   1 
ATOM   4690  C CA  . PRO B 1 136 ? -54.212 65.483  17.352 1.00 80.43  ? 144 PRO B CA  1 
ATOM   4691  C C   . PRO B 1 136 ? -54.062 64.506  16.189 1.00 66.76  ? 144 PRO B C   1 
ATOM   4692  O O   . PRO B 1 136 ? -54.868 64.548  15.270 1.00 61.57  ? 144 PRO B O   1 
ATOM   4693  C CB  . PRO B 1 136 ? -53.600 66.851  16.964 1.00 83.45  ? 144 PRO B CB  1 
ATOM   4694  C CG  . PRO B 1 136 ? -52.208 66.744  17.572 1.00 122.38 ? 144 PRO B CG  1 
ATOM   4695  C CD  . PRO B 1 136 ? -52.426 66.028  18.921 1.00 88.38  ? 144 PRO B CD  1 
ATOM   4696  N N   . ASP B 1 137 ? -53.056 63.629  16.233 1.00 63.72  ? 145 ASP B N   1 
ATOM   4697  C CA  . ASP B 1 137 ? -52.913 62.638  15.183 1.00 65.75  ? 145 ASP B CA  1 
ATOM   4698  C C   . ASP B 1 137 ? -53.581 61.309  15.555 1.00 76.00  ? 145 ASP B C   1 
ATOM   4699  O O   . ASP B 1 137 ? -53.311 60.308  14.883 1.00 68.28  ? 145 ASP B O   1 
ATOM   4700  C CB  . ASP B 1 137 ? -51.438 62.398  14.938 1.00 77.33  ? 145 ASP B CB  1 
ATOM   4701  C CG  . ASP B 1 137 ? -50.741 63.433  14.090 1.00 107.62 ? 145 ASP B CG  1 
ATOM   4702  O OD1 . ASP B 1 137 ? -51.419 64.160  13.332 1.00 123.48 ? 145 ASP B OD1 1 
ATOM   4703  O OD2 . ASP B 1 137 ? -49.512 63.390  14.106 1.00 105.11 ? 145 ASP B OD2 1 
ATOM   4704  N N   . GLY B 1 138 ? -54.368 61.278  16.657 1.00 68.25  ? 146 GLY B N   1 
ATOM   4705  C CA  . GLY B 1 138 ? -55.181 60.126  17.046 1.00 79.29  ? 146 GLY B CA  1 
ATOM   4706  C C   . GLY B 1 138 ? -54.562 59.354  18.225 1.00 90.28  ? 146 GLY B C   1 
ATOM   4707  O O   . GLY B 1 138 ? -54.876 58.175  18.432 1.00 87.94  ? 146 GLY B O   1 
ATOM   4708  N N   . GLY B 1 139 ? -53.647 60.013  18.962 1.00 78.91  ? 147 GLY B N   1 
ATOM   4709  C CA  . GLY B 1 139 ? -53.088 59.442  20.177 1.00 78.82  ? 147 GLY B CA  1 
ATOM   4710  C C   . GLY B 1 139 ? -54.112 59.470  21.308 1.00 79.42  ? 147 GLY B C   1 
ATOM   4711  O O   . GLY B 1 139 ? -55.168 60.065  21.130 1.00 117.70 ? 147 GLY B O   1 
ATOM   4712  N N   . HIS B 1 140 ? -53.806 58.825  22.457 1.00 66.54  ? 148 HIS B N   1 
ATOM   4713  C CA  . HIS B 1 140 ? -54.632 58.993  23.651 1.00 64.62  ? 148 HIS B CA  1 
ATOM   4714  C C   . HIS B 1 140 ? -53.904 59.825  24.697 1.00 68.18  ? 148 HIS B C   1 
ATOM   4715  O O   . HIS B 1 140 ? -52.686 59.730  24.778 1.00 58.93  ? 148 HIS B O   1 
ATOM   4716  C CB  . HIS B 1 140 ? -55.060 57.673  24.287 1.00 70.26  ? 148 HIS B CB  1 
ATOM   4717  C CG  . HIS B 1 140 ? -56.064 57.931  25.385 1.00 77.18  ? 148 HIS B CG  1 
ATOM   4718  N ND1 . HIS B 1 140 ? -56.133 57.311  26.619 1.00 64.81  ? 148 HIS B ND1 1 
ATOM   4719  C CD2 . HIS B 1 140 ? -57.015 58.926  25.403 1.00 89.90  ? 148 HIS B CD2 1 
ATOM   4720  C CE1 . HIS B 1 140 ? -57.124 57.870  27.327 1.00 84.96  ? 148 HIS B CE1 1 
ATOM   4721  N NE2 . HIS B 1 140 ? -57.652 58.868  26.626 1.00 103.98 ? 148 HIS B NE2 1 
ATOM   4722  N N   . LEU B 1 141 ? -54.646 60.623  25.495 1.00 70.52  ? 149 LEU B N   1 
ATOM   4723  C CA  . LEU B 1 141 ? -54.080 61.417  26.597 1.00 72.62  ? 149 LEU B CA  1 
ATOM   4724  C C   . LEU B 1 141 ? -53.012 60.640  27.356 1.00 63.12  ? 149 LEU B C   1 
ATOM   4725  O O   . LEU B 1 141 ? -51.910 61.150  27.521 1.00 73.13  ? 149 LEU B O   1 
ATOM   4726  C CB  . LEU B 1 141 ? -55.050 61.995  27.626 1.00 64.90  ? 149 LEU B CB  1 
ATOM   4727  C CG  . LEU B 1 141 ? -56.166 62.915  27.128 1.00 51.19  ? 149 LEU B CG  1 
ATOM   4728  C CD1 . LEU B 1 141 ? -56.979 62.164  26.029 1.00 51.85  ? 149 LEU B CD1 1 
ATOM   4729  C CD2 . LEU B 1 141 ? -57.037 63.369  28.354 1.00 28.60  ? 149 LEU B CD2 1 
ATOM   4730  N N   . THR B 1 142 ? -53.347 59.421  27.807 1.00 58.24  ? 150 THR B N   1 
ATOM   4731  C CA  . THR B 1 142 ? -52.413 58.606  28.584 1.00 79.32  ? 150 THR B CA  1 
ATOM   4732  C C   . THR B 1 142 ? -51.099 58.281  27.848 1.00 79.96  ? 150 THR B C   1 
ATOM   4733  O O   . THR B 1 142 ? -50.174 57.749  28.477 1.00 45.08  ? 150 THR B O   1 
ATOM   4734  C CB  . THR B 1 142 ? -53.092 57.322  29.053 1.00 76.80  ? 150 THR B CB  1 
ATOM   4735  O OG1 . THR B 1 142 ? -53.403 56.623  27.852 1.00 59.83  ? 150 THR B OG1 1 
ATOM   4736  C CG2 . THR B 1 142 ? -54.313 57.622  29.906 1.00 73.94  ? 150 THR B CG2 1 
ATOM   4737  N N   . HIS B 1 143 ? -51.006 58.595  26.541 1.00 69.91  ? 151 HIS B N   1 
ATOM   4738  C CA  . HIS B 1 143 ? -49.809 58.332  25.768 1.00 69.40  ? 151 HIS B CA  1 
ATOM   4739  C C   . HIS B 1 143 ? -48.954 59.589  25.723 1.00 79.34  ? 151 HIS B C   1 
ATOM   4740  O O   . HIS B 1 143 ? -48.006 59.675  24.942 1.00 96.21  ? 151 HIS B O   1 
ATOM   4741  C CB  . HIS B 1 143 ? -50.176 57.946  24.329 1.00 83.31  ? 151 HIS B CB  1 
ATOM   4742  C CG  . HIS B 1 143 ? -51.017 56.739  24.194 1.00 81.93  ? 151 HIS B CG  1 
ATOM   4743  N ND1 . HIS B 1 143 ? -51.418 56.274  22.965 1.00 89.42  ? 151 HIS B ND1 1 
ATOM   4744  C CD2 . HIS B 1 143 ? -51.459 55.870  25.116 1.00 86.49  ? 151 HIS B CD2 1 
ATOM   4745  C CE1 . HIS B 1 143 ? -52.134 55.159  23.166 1.00 114.15 ? 151 HIS B CE1 1 
ATOM   4746  N NE2 . HIS B 1 143 ? -52.206 54.917  24.467 1.00 87.87  ? 151 HIS B NE2 1 
ATOM   4747  N N   . GLY B 1 144 ? -49.316 60.559  26.555 1.00 86.36  ? 152 GLY B N   1 
ATOM   4748  C CA  . GLY B 1 144 ? -48.553 61.793  26.660 1.00 77.59  ? 152 GLY B CA  1 
ATOM   4749  C C   . GLY B 1 144 ? -49.366 62.923  26.047 1.00 89.07  ? 152 GLY B C   1 
ATOM   4750  O O   . GLY B 1 144 ? -50.080 62.684  25.080 1.00 75.48  ? 152 GLY B O   1 
ATOM   4751  N N   . PHE B 1 145 ? -49.363 64.115  26.654 1.00 95.24  ? 153 PHE B N   1 
ATOM   4752  C CA  . PHE B 1 145 ? -50.002 65.243  26.000 1.00 103.84 ? 153 PHE B CA  1 
ATOM   4753  C C   . PHE B 1 145 ? -49.660 66.515  26.750 1.00 106.27 ? 153 PHE B C   1 
ATOM   4754  O O   . PHE B 1 145 ? -49.978 66.648  27.931 1.00 95.24  ? 153 PHE B O   1 
ATOM   4755  C CB  . PHE B 1 145 ? -51.519 65.033  25.927 1.00 118.45 ? 153 PHE B CB  1 
ATOM   4756  C CG  . PHE B 1 145 ? -52.245 66.219  25.327 1.00 117.90 ? 153 PHE B CG  1 
ATOM   4757  C CD1 . PHE B 1 145 ? -51.723 66.872  24.216 1.00 97.45  ? 153 PHE B CD1 1 
ATOM   4758  C CD2 . PHE B 1 145 ? -53.364 66.760  25.952 1.00 113.12 ? 153 PHE B CD2 1 
ATOM   4759  C CE1 . PHE B 1 145 ? -52.371 67.974  23.674 1.00 87.74  ? 153 PHE B CE1 1 
ATOM   4760  C CE2 . PHE B 1 145 ? -54.004 67.870  25.411 1.00 101.02 ? 153 PHE B CE2 1 
ATOM   4761  C CZ  . PHE B 1 145 ? -53.520 68.460  24.260 1.00 84.42  ? 153 PHE B CZ  1 
ATOM   4762  N N   . MET B 1 146 ? -49.032 67.444  26.028 1.00 83.22  ? 154 MET B N   1 
ATOM   4763  C CA  . MET B 1 146 ? -48.630 68.697  26.638 1.00 83.75  ? 154 MET B CA  1 
ATOM   4764  C C   . MET B 1 146 ? -48.553 69.773  25.567 1.00 98.25  ? 154 MET B C   1 
ATOM   4765  O O   . MET B 1 146 ? -48.323 69.480  24.397 1.00 126.59 ? 154 MET B O   1 
ATOM   4766  C CB  . MET B 1 146 ? -47.300 68.579  27.407 1.00 71.13  ? 154 MET B CB  1 
ATOM   4767  C CG  . MET B 1 146 ? -46.088 68.234  26.561 1.00 68.63  ? 154 MET B CG  1 
ATOM   4768  S SD  . MET B 1 146 ? -44.495 68.185  27.430 1.00 86.39  ? 154 MET B SD  1 
ATOM   4769  C CE  . MET B 1 146 ? -44.121 69.946  27.513 1.00 76.78  ? 154 MET B CE  1 
ATOM   4770  N N   . THR B 1 147 ? -48.757 71.027  25.998 1.00 100.96 ? 155 THR B N   1 
ATOM   4771  C CA  . THR B 1 147 ? -48.689 72.207  25.156 1.00 76.36  ? 155 THR B CA  1 
ATOM   4772  C C   . THR B 1 147 ? -47.441 73.000  25.561 1.00 94.36  ? 155 THR B C   1 
ATOM   4773  O O   . THR B 1 147 ? -46.687 72.571  26.442 1.00 107.81 ? 155 THR B O   1 
ATOM   4774  C CB  . THR B 1 147 ? -50.002 72.955  25.401 1.00 63.23  ? 155 THR B CB  1 
ATOM   4775  O OG1 . THR B 1 147 ? -49.942 73.572  26.686 1.00 43.95  ? 155 THR B OG1 1 
ATOM   4776  C CG2 . THR B 1 147 ? -51.193 72.017  25.408 1.00 45.01  ? 155 THR B CG2 1 
ATOM   4777  N N   . ASP B 1 148 ? -47.141 74.115  24.878 1.00 86.51  ? 156 ASP B N   1 
ATOM   4778  C CA  . ASP B 1 148 ? -46.002 74.928  25.291 1.00 82.23  ? 156 ASP B CA  1 
ATOM   4779  C C   . ASP B 1 148 ? -46.232 75.447  26.732 1.00 97.35  ? 156 ASP B C   1 
ATOM   4780  O O   . ASP B 1 148 ? -45.266 75.660  27.509 1.00 80.98  ? 156 ASP B O   1 
ATOM   4781  C CB  . ASP B 1 148 ? -45.599 75.917  24.215 1.00 83.92  ? 156 ASP B CB  1 
ATOM   4782  C CG  . ASP B 1 148 ? -46.597 77.066  24.117 1.00 115.02 ? 156 ASP B CG  1 
ATOM   4783  O OD1 . ASP B 1 148 ? -47.810 76.755  23.885 1.00 86.22  ? 156 ASP B OD1 1 
ATOM   4784  O OD2 . ASP B 1 148 ? -46.172 78.255  24.291 1.00 112.40 ? 156 ASP B OD2 1 
ATOM   4785  N N   . LYS B 1 149 ? -47.516 75.584  27.139 1.00 80.85  ? 157 LYS B N   1 
ATOM   4786  C CA  . LYS B 1 149 ? -47.906 76.312  28.354 1.00 74.01  ? 157 LYS B CA  1 
ATOM   4787  C C   . LYS B 1 149 ? -48.140 75.388  29.556 1.00 92.79  ? 157 LYS B C   1 
ATOM   4788  O O   . LYS B 1 149 ? -47.977 75.819  30.698 1.00 119.74 ? 157 LYS B O   1 
ATOM   4789  C CB  . LYS B 1 149 ? -49.026 77.356  28.189 1.00 59.65  ? 157 LYS B CB  1 
ATOM   4790  C CG  . LYS B 1 149 ? -49.000 78.371  26.993 1.00 74.76  ? 157 LYS B CG  1 
ATOM   4791  C CD  . LYS B 1 149 ? -48.154 79.631  26.732 1.00 64.16  ? 157 LYS B CD  1 
ATOM   4792  C CE  . LYS B 1 149 ? -48.365 80.134  25.291 1.00 98.01  ? 157 LYS B CE  1 
ATOM   4793  N NZ  . LYS B 1 149 ? -47.435 80.844  24.371 1.00 75.21  ? 157 LYS B NZ  1 
ATOM   4794  N N   . LYS B 1 150 ? -48.529 74.123  29.349 1.00 87.84  ? 158 LYS B N   1 
ATOM   4795  C CA  . LYS B 1 150 ? -48.643 73.233  30.494 1.00 92.34  ? 158 LYS B CA  1 
ATOM   4796  C C   . LYS B 1 150 ? -48.634 71.760  30.096 1.00 109.49 ? 158 LYS B C   1 
ATOM   4797  O O   . LYS B 1 150 ? -49.055 71.378  29.010 1.00 126.23 ? 158 LYS B O   1 
ATOM   4798  C CB  . LYS B 1 150 ? -49.919 73.341  31.338 1.00 74.70  ? 158 LYS B CB  1 
ATOM   4799  C CG  . LYS B 1 150 ? -49.717 72.697  32.719 1.00 71.46  ? 158 LYS B CG  1 
ATOM   4800  C CD  . LYS B 1 150 ? -50.987 72.212  33.436 1.00 60.62  ? 158 LYS B CD  1 
ATOM   4801  C CE  . LYS B 1 150 ? -52.343 72.652  32.845 1.00 68.68  ? 158 LYS B CE  1 
ATOM   4802  N NZ  . LYS B 1 150 ? -53.482 72.417  33.745 1.00 60.22  ? 158 LYS B NZ  1 
ATOM   4803  N N   . LYS B 1 151 ? -48.180 70.933  31.050 1.00 98.10  ? 159 LYS B N   1 
ATOM   4804  C CA  . LYS B 1 151 ? -48.217 69.493  30.851 1.00 72.45  ? 159 LYS B CA  1 
ATOM   4805  C C   . LYS B 1 151 ? -49.602 69.056  31.271 1.00 61.02  ? 159 LYS B C   1 
ATOM   4806  O O   . LYS B 1 151 ? -49.851 69.099  32.467 1.00 73.36  ? 159 LYS B O   1 
ATOM   4807  C CB  . LYS B 1 151 ? -47.125 68.804  31.675 1.00 59.07  ? 159 LYS B CB  1 
ATOM   4808  C CG  . LYS B 1 151 ? -45.709 69.271  31.279 1.00 60.28  ? 159 LYS B CG  1 
ATOM   4809  C CD  . LYS B 1 151 ? -44.670 68.430  32.004 1.00 69.01  ? 159 LYS B CD  1 
ATOM   4810  C CE  . LYS B 1 151 ? -43.411 68.998  32.556 1.00 72.66  ? 159 LYS B CE  1 
ATOM   4811  N NZ  . LYS B 1 151 ? -42.460 67.873  32.511 1.00 102.92 ? 159 LYS B NZ  1 
ATOM   4812  N N   . ILE B 1 152 ? -50.457 68.612  30.340 1.00 39.76  ? 160 ILE B N   1 
ATOM   4813  C CA  . ILE B 1 152 ? -51.857 68.316  30.623 1.00 40.86  ? 160 ILE B CA  1 
ATOM   4814  C C   . ILE B 1 152 ? -52.026 66.903  31.175 1.00 48.31  ? 160 ILE B C   1 
ATOM   4815  O O   . ILE B 1 152 ? -52.530 66.746  32.283 1.00 42.68  ? 160 ILE B O   1 
ATOM   4816  C CB  . ILE B 1 152 ? -52.698 68.347  29.326 1.00 60.79  ? 160 ILE B CB  1 
ATOM   4817  C CG1 . ILE B 1 152 ? -52.487 69.611  28.419 1.00 69.12  ? 160 ILE B CG1 1 
ATOM   4818  C CG2 . ILE B 1 152 ? -54.162 67.928  29.574 1.00 39.73  ? 160 ILE B CG2 1 
ATOM   4819  C CD1 . ILE B 1 152 ? -52.227 70.922  29.162 1.00 78.98  ? 160 ILE B CD1 1 
ATOM   4820  N N   . SER B 1 153 ? -51.691 65.874  30.363 1.00 54.15  ? 161 SER B N   1 
ATOM   4821  C CA  . SER B 1 153 ? -51.880 64.490  30.767 1.00 54.90  ? 161 SER B CA  1 
ATOM   4822  C C   . SER B 1 153 ? -50.896 64.159  31.883 1.00 67.77  ? 161 SER B C   1 
ATOM   4823  O O   . SER B 1 153 ? -49.751 64.625  31.850 1.00 52.66  ? 161 SER B O   1 
ATOM   4824  C CB  . SER B 1 153 ? -51.557 63.604  29.634 1.00 66.65  ? 161 SER B CB  1 
ATOM   4825  O OG  . SER B 1 153 ? -51.482 62.265  30.091 1.00 89.56  ? 161 SER B OG  1 
ATOM   4826  N N   . ALA B 1 154 ? -51.359 63.376  32.870 1.00 77.64  ? 162 ALA B N   1 
ATOM   4827  C CA  . ALA B 1 154 ? -50.503 62.941  33.966 1.00 69.09  ? 162 ALA B CA  1 
ATOM   4828  C C   . ALA B 1 154 ? -49.249 62.238  33.456 1.00 69.56  ? 162 ALA B C   1 
ATOM   4829  O O   . ALA B 1 154 ? -48.173 62.403  34.040 1.00 83.42  ? 162 ALA B O   1 
ATOM   4830  C CB  . ALA B 1 154 ? -51.256 62.051  34.895 1.00 84.56  ? 162 ALA B CB  1 
ATOM   4831  N N   . THR B 1 155 ? -49.386 61.528  32.325 1.00 66.91  ? 163 THR B N   1 
ATOM   4832  C CA  . THR B 1 155 ? -48.243 60.919  31.654 1.00 66.60  ? 163 THR B CA  1 
ATOM   4833  C C   . THR B 1 155 ? -47.205 62.000  31.367 1.00 65.60  ? 163 THR B C   1 
ATOM   4834  O O   . THR B 1 155 ? -46.005 61.770  31.519 1.00 69.09  ? 163 THR B O   1 
ATOM   4835  C CB  . THR B 1 155 ? -48.675 60.240  30.362 1.00 59.53  ? 163 THR B CB  1 
ATOM   4836  O OG1 . THR B 1 155 ? -49.693 59.295  30.684 1.00 71.25  ? 163 THR B OG1 1 
ATOM   4837  C CG2 . THR B 1 155 ? -47.554 59.389  29.811 1.00 65.95  ? 163 THR B CG2 1 
ATOM   4838  N N   . SER B 1 156 ? -47.670 63.169  30.925 1.00 62.75  ? 164 SER B N   1 
ATOM   4839  C CA  . SER B 1 156 ? -46.747 64.241  30.570 1.00 82.21  ? 164 SER B CA  1 
ATOM   4840  C C   . SER B 1 156 ? -46.285 65.054  31.785 1.00 90.77  ? 164 SER B C   1 
ATOM   4841  O O   . SER B 1 156 ? -45.309 65.805  31.683 1.00 111.50 ? 164 SER B O   1 
ATOM   4842  C CB  . SER B 1 156 ? -47.391 65.140  29.564 1.00 106.45 ? 164 SER B CB  1 
ATOM   4843  O OG  . SER B 1 156 ? -47.274 64.600  28.262 1.00 123.14 ? 164 SER B OG  1 
ATOM   4844  N N   . ILE B 1 157 ? -47.018 64.956  32.899 1.00 73.09  ? 165 ILE B N   1 
ATOM   4845  C CA  . ILE B 1 157 ? -46.696 65.660  34.133 1.00 74.04  ? 165 ILE B CA  1 
ATOM   4846  C C   . ILE B 1 157 ? -45.572 64.959  34.873 1.00 83.75  ? 165 ILE B C   1 
ATOM   4847  O O   . ILE B 1 157 ? -44.648 65.643  35.300 1.00 96.77  ? 165 ILE B O   1 
ATOM   4848  C CB  . ILE B 1 157 ? -47.933 65.712  35.048 1.00 75.67  ? 165 ILE B CB  1 
ATOM   4849  C CG1 . ILE B 1 157 ? -49.043 66.539  34.367 1.00 58.89  ? 165 ILE B CG1 1 
ATOM   4850  C CG2 . ILE B 1 157 ? -47.632 66.106  36.505 1.00 54.69  ? 165 ILE B CG2 1 
ATOM   4851  C CD1 . ILE B 1 157 ? -50.340 66.476  35.140 1.00 30.97  ? 165 ILE B CD1 1 
ATOM   4852  N N   . PHE B 1 158 ? -45.686 63.628  35.055 1.00 79.17  ? 166 PHE B N   1 
ATOM   4853  C CA  . PHE B 1 158 ? -44.716 62.916  35.870 1.00 88.25  ? 166 PHE B CA  1 
ATOM   4854  C C   . PHE B 1 158 ? -43.616 62.276  35.018 1.00 98.16  ? 166 PHE B C   1 
ATOM   4855  O O   . PHE B 1 158 ? -42.689 61.665  35.563 1.00 108.77 ? 166 PHE B O   1 
ATOM   4856  C CB  . PHE B 1 158 ? -45.440 61.811  36.626 1.00 74.51  ? 166 PHE B CB  1 
ATOM   4857  C CG  . PHE B 1 158 ? -46.491 62.286  37.596 1.00 66.71  ? 166 PHE B CG  1 
ATOM   4858  C CD1 . PHE B 1 158 ? -46.130 62.656  38.883 1.00 59.46  ? 166 PHE B CD1 1 
ATOM   4859  C CD2 . PHE B 1 158 ? -47.845 62.258  37.243 1.00 87.51  ? 166 PHE B CD2 1 
ATOM   4860  C CE1 . PHE B 1 158 ? -47.116 63.045  39.815 1.00 72.37  ? 166 PHE B CE1 1 
ATOM   4861  C CE2 . PHE B 1 158 ? -48.825 62.640  38.164 1.00 107.61 ? 166 PHE B CE2 1 
ATOM   4862  C CZ  . PHE B 1 158 ? -48.461 63.036  39.460 1.00 83.11  ? 166 PHE B CZ  1 
ATOM   4863  N N   . PHE B 1 159 ? -43.775 62.271  33.679 1.00 74.03  ? 167 PHE B N   1 
ATOM   4864  C CA  . PHE B 1 159 ? -42.723 61.787  32.777 1.00 68.20  ? 167 PHE B CA  1 
ATOM   4865  C C   . PHE B 1 159 ? -42.478 62.801  31.666 1.00 75.73  ? 167 PHE B C   1 
ATOM   4866  O O   . PHE B 1 159 ? -43.301 63.694  31.450 1.00 119.79 ? 167 PHE B O   1 
ATOM   4867  C CB  . PHE B 1 159 ? -43.094 60.419  32.199 1.00 58.76  ? 167 PHE B CB  1 
ATOM   4868  C CG  . PHE B 1 159 ? -43.607 59.440  33.242 1.00 62.55  ? 167 PHE B CG  1 
ATOM   4869  C CD1 . PHE B 1 159 ? -42.732 58.681  34.020 1.00 68.25  ? 167 PHE B CD1 1 
ATOM   4870  C CD2 . PHE B 1 159 ? -44.971 59.253  33.429 1.00 73.98  ? 167 PHE B CD2 1 
ATOM   4871  C CE1 . PHE B 1 159 ? -43.206 57.728  34.929 1.00 79.77  ? 167 PHE B CE1 1 
ATOM   4872  C CE2 . PHE B 1 159 ? -45.438 58.336  34.378 1.00 92.61  ? 167 PHE B CE2 1 
ATOM   4873  C CZ  . PHE B 1 159 ? -44.567 57.556  35.121 1.00 71.64  ? 167 PHE B CZ  1 
ATOM   4874  N N   . GLU B 1 160 ? -41.369 62.663  30.939 1.00 62.39  ? 168 GLU B N   1 
ATOM   4875  C CA  . GLU B 1 160 ? -41.120 63.555  29.807 1.00 72.22  ? 168 GLU B CA  1 
ATOM   4876  C C   . GLU B 1 160 ? -41.602 62.902  28.500 1.00 81.39  ? 168 GLU B C   1 
ATOM   4877  O O   . GLU B 1 160 ? -41.000 61.914  28.002 1.00 66.78  ? 168 GLU B O   1 
ATOM   4878  C CB  . GLU B 1 160 ? -39.651 63.971  29.762 1.00 48.36  ? 168 GLU B CB  1 
ATOM   4879  C CG  . GLU B 1 160 ? -39.138 64.667  31.013 1.00 69.10  ? 168 GLU B CG  1 
ATOM   4880  C CD  . GLU B 1 160 ? -39.800 65.933  31.516 1.00 91.59  ? 168 GLU B CD  1 
ATOM   4881  O OE1 . GLU B 1 160 ? -40.007 66.886  30.712 1.00 64.61  ? 168 GLU B OE1 1 
ATOM   4882  O OE2 . GLU B 1 160 ? -40.042 65.928  32.736 1.00 98.74  ? 168 GLU B OE2 1 
ATOM   4883  N N   . SER B 1 161 ? -42.673 63.483  27.912 1.00 68.59  ? 169 SER B N   1 
ATOM   4884  C CA  . SER B 1 161 ? -43.204 62.786  26.741 1.00 85.15  ? 169 SER B CA  1 
ATOM   4885  C C   . SER B 1 161 ? -42.994 63.623  25.500 1.00 70.52  ? 169 SER B C   1 
ATOM   4886  O O   . SER B 1 161 ? -42.983 64.834  25.623 1.00 106.08 ? 169 SER B O   1 
ATOM   4887  C CB  . SER B 1 161 ? -44.678 62.414  26.837 1.00 97.60  ? 169 SER B CB  1 
ATOM   4888  O OG  . SER B 1 161 ? -45.455 63.591  26.710 1.00 95.87  ? 169 SER B OG  1 
ATOM   4889  N N   . MET B 1 162 ? -42.893 62.974  24.344 1.00 63.51  ? 170 MET B N   1 
ATOM   4890  C CA  . MET B 1 162 ? -42.837 63.626  23.052 1.00 63.96  ? 170 MET B CA  1 
ATOM   4891  C C   . MET B 1 162 ? -43.615 62.771  22.070 1.00 58.62  ? 170 MET B C   1 
ATOM   4892  O O   . MET B 1 162 ? -43.423 61.550  22.043 1.00 57.58  ? 170 MET B O   1 
ATOM   4893  C CB  . MET B 1 162 ? -41.387 63.669  22.506 1.00 59.49  ? 170 MET B CB  1 
ATOM   4894  C CG  . MET B 1 162 ? -41.308 64.492  21.242 1.00 52.05  ? 170 MET B CG  1 
ATOM   4895  S SD  . MET B 1 162 ? -39.638 65.123  21.000 1.00 78.49  ? 170 MET B SD  1 
ATOM   4896  C CE  . MET B 1 162 ? -39.127 63.708  20.042 1.00 65.46  ? 170 MET B CE  1 
ATOM   4897  N N   . PRO B 1 163 ? -44.456 63.372  21.201 1.00 62.49  ? 171 PRO B N   1 
ATOM   4898  C CA  . PRO B 1 163 ? -45.149 62.618  20.134 1.00 55.31  ? 171 PRO B CA  1 
ATOM   4899  C C   . PRO B 1 163 ? -44.403 62.248  18.851 1.00 60.87  ? 171 PRO B C   1 
ATOM   4900  O O   . PRO B 1 163 ? -43.424 62.907  18.453 1.00 60.03  ? 171 PRO B O   1 
ATOM   4901  C CB  . PRO B 1 163 ? -46.336 63.510  19.798 1.00 45.82  ? 171 PRO B CB  1 
ATOM   4902  C CG  . PRO B 1 163 ? -45.800 64.906  20.047 1.00 65.79  ? 171 PRO B CG  1 
ATOM   4903  C CD  . PRO B 1 163 ? -44.825 64.796  21.253 1.00 66.02  ? 171 PRO B CD  1 
ATOM   4904  N N   . TYR B 1 164 ? -44.873 61.159  18.215 1.00 77.72  ? 172 TYR B N   1 
ATOM   4905  C CA  . TYR B 1 164 ? -44.530 60.841  16.832 1.00 91.25  ? 172 TYR B CA  1 
ATOM   4906  C C   . TYR B 1 164 ? -45.803 61.118  16.044 1.00 95.63  ? 172 TYR B C   1 
ATOM   4907  O O   . TYR B 1 164 ? -46.906 60.893  16.572 1.00 59.04  ? 172 TYR B O   1 
ATOM   4908  C CB  . TYR B 1 164 ? -43.980 59.428  16.567 1.00 72.24  ? 172 TYR B CB  1 
ATOM   4909  C CG  . TYR B 1 164 ? -44.782 58.205  17.022 1.00 52.45  ? 172 TYR B CG  1 
ATOM   4910  C CD1 . TYR B 1 164 ? -45.855 57.735  16.290 1.00 59.79  ? 172 TYR B CD1 1 
ATOM   4911  C CD2 . TYR B 1 164 ? -44.501 57.504  18.188 1.00 60.91  ? 172 TYR B CD2 1 
ATOM   4912  C CE1 . TYR B 1 164 ? -46.576 56.599  16.632 1.00 60.58  ? 172 TYR B CE1 1 
ATOM   4913  C CE2 . TYR B 1 164 ? -45.231 56.382  18.567 1.00 71.75  ? 172 TYR B CE2 1 
ATOM   4914  C CZ  . TYR B 1 164 ? -46.268 55.904  17.780 1.00 81.02  ? 172 TYR B CZ  1 
ATOM   4915  O OH  . TYR B 1 164 ? -47.085 54.830  18.085 1.00 105.00 ? 172 TYR B OH  1 
ATOM   4916  N N   . LYS B 1 165 ? -45.645 61.595  14.803 1.00 97.60  ? 173 LYS B N   1 
ATOM   4917  C CA  . LYS B 1 165 ? -46.809 62.165  14.139 1.00 77.20  ? 173 LYS B CA  1 
ATOM   4918  C C   . LYS B 1 165 ? -47.165 61.328  12.922 1.00 79.72  ? 173 LYS B C   1 
ATOM   4919  O O   . LYS B 1 165 ? -46.384 60.458  12.517 1.00 81.44  ? 173 LYS B O   1 
ATOM   4920  C CB  . LYS B 1 165 ? -46.662 63.643  13.780 1.00 75.17  ? 173 LYS B CB  1 
ATOM   4921  C CG  . LYS B 1 165 ? -46.564 64.606  14.951 1.00 76.32  ? 173 LYS B CG  1 
ATOM   4922  C CD  . LYS B 1 165 ? -46.880 66.044  14.559 1.00 74.75  ? 173 LYS B CD  1 
ATOM   4923  C CE  . LYS B 1 165 ? -48.224 66.249  13.879 1.00 74.43  ? 173 LYS B CE  1 
ATOM   4924  N NZ  . LYS B 1 165 ? -49.106 66.471  15.015 1.00 70.11  ? 173 LYS B NZ  1 
ATOM   4925  N N   . VAL B 1 166 ? -48.399 61.551  12.445 1.00 69.78  ? 174 VAL B N   1 
ATOM   4926  C CA  . VAL B 1 166 ? -48.946 60.916  11.260 1.00 78.13  ? 174 VAL B CA  1 
ATOM   4927  C C   . VAL B 1 166 ? -48.728 61.891  10.121 1.00 84.57  ? 174 VAL B C   1 
ATOM   4928  O O   . VAL B 1 166 ? -49.041 63.070  10.267 1.00 92.99  ? 174 VAL B O   1 
ATOM   4929  C CB  . VAL B 1 166 ? -50.450 60.661  11.478 1.00 88.32  ? 174 VAL B CB  1 
ATOM   4930  C CG1 . VAL B 1 166 ? -51.341 60.506  10.236 1.00 68.26  ? 174 VAL B CG1 1 
ATOM   4931  C CG2 . VAL B 1 166 ? -50.719 59.656  12.584 1.00 121.12 ? 174 VAL B CG2 1 
ATOM   4932  N N   . ASN B 1 167 ? -48.279 61.354  8.986  1.00 90.93  ? 175 ASN B N   1 
ATOM   4933  C CA  . ASN B 1 167 ? -48.009 62.128  7.795  1.00 89.58  ? 175 ASN B CA  1 
ATOM   4934  C C   . ASN B 1 167 ? -49.308 62.777  7.340  1.00 102.81 ? 175 ASN B C   1 
ATOM   4935  O O   . ASN B 1 167 ? -50.324 62.113  7.084  1.00 105.07 ? 175 ASN B O   1 
ATOM   4936  C CB  . ASN B 1 167 ? -47.696 61.171  6.657  1.00 77.09  ? 175 ASN B CB  1 
ATOM   4937  C CG  . ASN B 1 167 ? -47.125 61.873  5.475  1.00 62.47  ? 175 ASN B CG  1 
ATOM   4938  O OD1 . ASN B 1 167 ? -47.730 62.818  4.948  1.00 73.51  ? 175 ASN B OD1 1 
ATOM   4939  N ND2 . ASN B 1 167 ? -45.983 61.363  5.043  1.00 120.99 ? 175 ASN B ND2 1 
ATOM   4940  N N   . PRO B 1 168 ? -49.356 64.120  7.275  1.00 90.49  ? 176 PRO B N   1 
ATOM   4941  C CA  . PRO B 1 168 ? -50.603 64.796  6.919  1.00 89.72  ? 176 PRO B CA  1 
ATOM   4942  C C   . PRO B 1 168 ? -51.025 64.493  5.472  1.00 97.78  ? 176 PRO B C   1 
ATOM   4943  O O   . PRO B 1 168 ? -52.193 64.637  5.138  1.00 127.18 ? 176 PRO B O   1 
ATOM   4944  C CB  . PRO B 1 168 ? -50.376 66.293  7.226  1.00 80.82  ? 176 PRO B CB  1 
ATOM   4945  C CG  . PRO B 1 168 ? -49.019 66.345  7.887  1.00 103.04 ? 176 PRO B CG  1 
ATOM   4946  C CD  . PRO B 1 168 ? -48.246 65.046  7.537  1.00 100.21 ? 176 PRO B CD  1 
ATOM   4947  N N   . ASP B 1 169 ? -50.088 64.055  4.623  1.00 72.50  ? 177 ASP B N   1 
ATOM   4948  C CA  . ASP B 1 169 ? -50.409 63.817  3.233  1.00 70.62  ? 177 ASP B CA  1 
ATOM   4949  C C   . ASP B 1 169 ? -50.903 62.412  2.956  1.00 72.24  ? 177 ASP B C   1 
ATOM   4950  O O   . ASP B 1 169 ? -51.471 62.246  1.907  1.00 81.37  ? 177 ASP B O   1 
ATOM   4951  C CB  . ASP B 1 169 ? -49.243 64.141  2.327  1.00 77.02  ? 177 ASP B CB  1 
ATOM   4952  C CG  . ASP B 1 169 ? -48.757 65.558  2.534  1.00 96.18  ? 177 ASP B CG  1 
ATOM   4953  O OD1 . ASP B 1 169 ? -49.603 66.418  2.871  1.00 113.89 ? 177 ASP B OD1 1 
ATOM   4954  O OD2 . ASP B 1 169 ? -47.566 65.785  2.311  1.00 93.66  ? 177 ASP B OD2 1 
ATOM   4955  N N   . THR B 1 170 ? -50.614 61.413  3.797  1.00 74.97  ? 178 THR B N   1 
ATOM   4956  C CA  . THR B 1 170 ? -50.995 60.024  3.565  1.00 66.03  ? 178 THR B CA  1 
ATOM   4957  C C   . THR B 1 170 ? -52.066 59.653  4.597  1.00 94.70  ? 178 THR B C   1 
ATOM   4958  O O   . THR B 1 170 ? -52.835 58.701  4.407  1.00 112.14 ? 178 THR B O   1 
ATOM   4959  C CB  . THR B 1 170 ? -49.764 59.107  3.701  1.00 67.01  ? 178 THR B CB  1 
ATOM   4960  O OG1 . THR B 1 170 ? -49.238 58.932  5.023  1.00 81.85  ? 178 THR B OG1 1 
ATOM   4961  C CG2 . THR B 1 170 ? -48.596 59.585  2.868  1.00 45.04  ? 178 THR B CG2 1 
ATOM   4962  N N   . GLY B 1 171 ? -52.046 60.348  5.752  1.00 72.10  ? 179 GLY B N   1 
ATOM   4963  C CA  . GLY B 1 171 ? -52.952 60.018  6.843  1.00 81.38  ? 179 GLY B CA  1 
ATOM   4964  C C   . GLY B 1 171 ? -52.472 58.814  7.650  1.00 85.54  ? 179 GLY B C   1 
ATOM   4965  O O   . GLY B 1 171 ? -53.154 58.390  8.595  1.00 57.84  ? 179 GLY B O   1 
ATOM   4966  N N   . TYR B 1 172 ? -51.260 58.338  7.303  1.00 91.76  ? 180 TYR B N   1 
ATOM   4967  C CA  . TYR B 1 172 ? -50.607 57.229  7.987  1.00 90.05  ? 180 TYR B CA  1 
ATOM   4968  C C   . TYR B 1 172 ? -49.589 57.751  8.983  1.00 87.60  ? 180 TYR B C   1 
ATOM   4969  O O   . TYR B 1 172 ? -49.049 58.847  8.866  1.00 99.94  ? 180 TYR B O   1 
ATOM   4970  C CB  . TYR B 1 172 ? -49.879 56.345  6.976  1.00 103.00 ? 180 TYR B CB  1 
ATOM   4971  C CG  . TYR B 1 172 ? -50.822 55.397  6.249  1.00 124.08 ? 180 TYR B CG  1 
ATOM   4972  C CD1 . TYR B 1 172 ? -51.675 55.804  5.219  1.00 114.51 ? 180 TYR B CD1 1 
ATOM   4973  C CD2 . TYR B 1 172 ? -50.882 54.069  6.662  1.00 112.13 ? 180 TYR B CD2 1 
ATOM   4974  C CE1 . TYR B 1 172 ? -52.545 54.905  4.626  1.00 131.26 ? 180 TYR B CE1 1 
ATOM   4975  C CE2 . TYR B 1 172 ? -51.770 53.170  6.100  1.00 101.10 ? 180 TYR B CE2 1 
ATOM   4976  C CZ  . TYR B 1 172 ? -52.588 53.587  5.063  1.00 133.05 ? 180 TYR B CZ  1 
ATOM   4977  O OH  . TYR B 1 172 ? -53.424 52.675  4.491  1.00 141.79 ? 180 TYR B OH  1 
ATOM   4978  N N   . ILE B 1 173 ? -49.307 56.914  9.965  1.00 84.43  ? 181 ILE B N   1 
ATOM   4979  C CA  . ILE B 1 173 ? -48.253 57.204  10.920 1.00 91.13  ? 181 ILE B CA  1 
ATOM   4980  C C   . ILE B 1 173 ? -46.956 57.269  10.130 1.00 81.25  ? 181 ILE B C   1 
ATOM   4981  O O   . ILE B 1 173 ? -46.682 56.385  9.312  1.00 77.09  ? 181 ILE B O   1 
ATOM   4982  C CB  . ILE B 1 173 ? -48.201 56.100  11.992 1.00 94.98  ? 181 ILE B CB  1 
ATOM   4983  C CG1 . ILE B 1 173 ? -49.357 56.209  12.953 1.00 97.23  ? 181 ILE B CG1 1 
ATOM   4984  C CG2 . ILE B 1 173 ? -46.912 56.160  12.763 1.00 82.00  ? 181 ILE B CG2 1 
ATOM   4985  C CD1 . ILE B 1 173 ? -49.514 54.993  13.848 1.00 128.86 ? 181 ILE B CD1 1 
ATOM   4986  N N   . ASN B 1 174 ? -46.171 58.304  10.430 1.00 72.25  ? 182 ASN B N   1 
ATOM   4987  C CA  . ASN B 1 174 ? -44.897 58.523  9.797  1.00 67.79  ? 182 ASN B CA  1 
ATOM   4988  C C   . ASN B 1 174 ? -43.818 57.829  10.630 1.00 79.43  ? 182 ASN B C   1 
ATOM   4989  O O   . ASN B 1 174 ? -43.152 58.460  11.501 1.00 82.76  ? 182 ASN B O   1 
ATOM   4990  C CB  . ASN B 1 174 ? -44.653 60.011  9.866  1.00 74.05  ? 182 ASN B CB  1 
ATOM   4991  C CG  . ASN B 1 174 ? -43.463 60.412  9.050  1.00 73.38  ? 182 ASN B CG  1 
ATOM   4992  O OD1 . ASN B 1 174 ? -42.425 59.723  9.030  1.00 65.95  ? 182 ASN B OD1 1 
ATOM   4993  N ND2 . ASN B 1 174 ? -43.611 61.571  8.433  1.00 51.77  ? 182 ASN B ND2 1 
ATOM   4994  N N   . TYR B 1 175 ? -43.695 56.506  10.386 1.00 62.91  ? 183 TYR B N   1 
ATOM   4995  C CA  . TYR B 1 175 ? -42.738 55.735  11.163 1.00 71.79  ? 183 TYR B CA  1 
ATOM   4996  C C   . TYR B 1 175 ? -41.322 56.233  10.876 1.00 69.99  ? 183 TYR B C   1 
ATOM   4997  O O   . TYR B 1 175 ? -40.430 56.012  11.696 1.00 57.17  ? 183 TYR B O   1 
ATOM   4998  C CB  . TYR B 1 175 ? -42.917 54.229  11.060 1.00 72.86  ? 183 TYR B CB  1 
ATOM   4999  C CG  . TYR B 1 175 ? -44.311 53.696  11.354 1.00 71.62  ? 183 TYR B CG  1 
ATOM   5000  C CD1 . TYR B 1 175 ? -45.302 53.606  10.376 1.00 102.51 ? 183 TYR B CD1 1 
ATOM   5001  C CD2 . TYR B 1 175 ? -44.592 53.157  12.578 1.00 70.03  ? 183 TYR B CD2 1 
ATOM   5002  C CE1 . TYR B 1 175 ? -46.546 53.050  10.618 1.00 118.06 ? 183 TYR B CE1 1 
ATOM   5003  C CE2 . TYR B 1 175 ? -45.839 52.612  12.855 1.00 112.59 ? 183 TYR B CE2 1 
ATOM   5004  C CZ  . TYR B 1 175 ? -46.820 52.532  11.868 1.00 125.11 ? 183 TYR B CZ  1 
ATOM   5005  O OH  . TYR B 1 175 ? -48.074 52.010  12.090 1.00 107.79 ? 183 TYR B OH  1 
ATOM   5006  N N   . ASP B 1 176 ? -41.133 56.977  9.775  1.00 65.37  ? 184 ASP B N   1 
ATOM   5007  C CA  . ASP B 1 176 ? -39.811 57.515  9.491  1.00 84.61  ? 184 ASP B CA  1 
ATOM   5008  C C   . ASP B 1 176 ? -39.422 58.589  10.503 1.00 81.49  ? 184 ASP B C   1 
ATOM   5009  O O   . ASP B 1 176 ? -38.311 58.604  11.013 1.00 73.58  ? 184 ASP B O   1 
ATOM   5010  C CB  . ASP B 1 176 ? -39.704 58.003  8.055  1.00 68.23  ? 184 ASP B CB  1 
ATOM   5011  C CG  . ASP B 1 176 ? -39.605 56.817  7.132  1.00 71.36  ? 184 ASP B CG  1 
ATOM   5012  O OD1 . ASP B 1 176 ? -40.489 55.933  7.201  1.00 92.49  ? 184 ASP B OD1 1 
ATOM   5013  O OD2 . ASP B 1 176 ? -38.558 56.713  6.509  1.00 64.48  ? 184 ASP B OD2 1 
ATOM   5014  N N   . GLN B 1 177 ? -40.346 59.514  10.729 1.00 78.09  ? 185 GLN B N   1 
ATOM   5015  C CA  . GLN B 1 177 ? -40.088 60.623  11.630 1.00 101.46 ? 185 GLN B CA  1 
ATOM   5016  C C   . GLN B 1 177 ? -39.855 60.057  13.035 1.00 94.23  ? 185 GLN B C   1 
ATOM   5017  O O   . GLN B 1 177 ? -39.115 60.656  13.830 1.00 70.66  ? 185 GLN B O   1 
ATOM   5018  C CB  . GLN B 1 177 ? -41.170 61.697  11.441 1.00 91.27  ? 185 GLN B CB  1 
ATOM   5019  C CG  . GLN B 1 177 ? -40.908 63.031  12.143 1.00 68.71  ? 185 GLN B CG  1 
ATOM   5020  C CD  . GLN B 1 177 ? -42.223 63.730  12.445 1.00 94.47  ? 185 GLN B CD  1 
ATOM   5021  O OE1 . GLN B 1 177 ? -43.159 63.125  12.997 1.00 104.72 ? 185 GLN B OE1 1 
ATOM   5022  N NE2 . GLN B 1 177 ? -42.340 64.996  12.044 1.00 70.90  ? 185 GLN B NE2 1 
ATOM   5023  N N   . LEU B 1 178 ? -40.580 58.969  13.362 1.00 94.02  ? 186 LEU B N   1 
ATOM   5024  C CA  . LEU B 1 178 ? -40.443 58.283  14.638 1.00 89.16  ? 186 LEU B CA  1 
ATOM   5025  C C   . LEU B 1 178 ? -38.988 57.898  14.812 1.00 80.08  ? 186 LEU B C   1 
ATOM   5026  O O   . LEU B 1 178 ? -38.350 58.200  15.839 1.00 73.47  ? 186 LEU B O   1 
ATOM   5027  C CB  . LEU B 1 178 ? -41.317 57.031  14.764 1.00 74.68  ? 186 LEU B CB  1 
ATOM   5028  C CG  . LEU B 1 178 ? -41.179 56.244  16.077 1.00 62.68  ? 186 LEU B CG  1 
ATOM   5029  C CD1 . LEU B 1 178 ? -40.564 57.133  17.190 1.00 44.32  ? 186 LEU B CD1 1 
ATOM   5030  C CD2 . LEU B 1 178 ? -42.518 55.506  16.536 1.00 46.54  ? 186 LEU B CD2 1 
ATOM   5031  N N   . GLU B 1 179 ? -38.529 57.167  13.792 1.00 88.08  ? 187 GLU B N   1 
ATOM   5032  C CA  . GLU B 1 179 ? -37.194 56.606  13.780 1.00 100.38 ? 187 GLU B CA  1 
ATOM   5033  C C   . GLU B 1 179 ? -36.168 57.685  14.114 1.00 78.07  ? 187 GLU B C   1 
ATOM   5034  O O   . GLU B 1 179 ? -35.351 57.447  15.038 1.00 78.64  ? 187 GLU B O   1 
ATOM   5035  C CB  . GLU B 1 179 ? -36.928 55.903  12.450 1.00 108.67 ? 187 GLU B CB  1 
ATOM   5036  C CG  . GLU B 1 179 ? -35.755 54.944  12.586 1.00 107.72 ? 187 GLU B CG  1 
ATOM   5037  C CD  . GLU B 1 179 ? -35.611 53.956  11.468 1.00 106.94 ? 187 GLU B CD  1 
ATOM   5038  O OE1 . GLU B 1 179 ? -36.524 53.085  11.298 1.00 85.47  ? 187 GLU B OE1 1 
ATOM   5039  O OE2 . GLU B 1 179 ? -34.583 54.110  10.777 1.00 115.08 ? 187 GLU B OE2 1 
ATOM   5040  N N   . GLU B 1 180 ? -36.256 58.811  13.349 1.00 43.34  ? 188 GLU B N   1 
ATOM   5041  C CA  . GLU B 1 180 ? -35.302 59.909  13.422 1.00 67.56  ? 188 GLU B CA  1 
ATOM   5042  C C   . GLU B 1 180 ? -35.327 60.527  14.828 1.00 64.17  ? 188 GLU B C   1 
ATOM   5043  O O   . GLU B 1 180 ? -34.282 60.690  15.484 1.00 65.86  ? 188 GLU B O   1 
ATOM   5044  C CB  . GLU B 1 180 ? -35.598 61.000  12.378 1.00 69.57  ? 188 GLU B CB  1 
ATOM   5045  C CG  . GLU B 1 180 ? -35.426 60.507  10.951 1.00 112.71 ? 188 GLU B CG  1 
ATOM   5046  C CD  . GLU B 1 180 ? -36.314 61.000  9.826  1.00 136.61 ? 188 GLU B CD  1 
ATOM   5047  O OE1 . GLU B 1 180 ? -37.239 61.788  10.066 1.00 137.78 ? 188 GLU B OE1 1 
ATOM   5048  O OE2 . GLU B 1 180 ? -36.080 60.606  8.651  1.00 144.39 ? 188 GLU B OE2 1 
ATOM   5049  N N   . ASN B 1 181 ? -36.532 60.873  15.286 1.00 43.57  ? 189 ASN B N   1 
ATOM   5050  C CA  . ASN B 1 181 ? -36.659 61.594  16.531 1.00 49.18  ? 189 ASN B CA  1 
ATOM   5051  C C   . ASN B 1 181 ? -36.253 60.697  17.702 1.00 55.62  ? 189 ASN B C   1 
ATOM   5052  O O   . ASN B 1 181 ? -35.718 61.209  18.695 1.00 46.35  ? 189 ASN B O   1 
ATOM   5053  C CB  . ASN B 1 181 ? -38.104 62.009  16.754 1.00 70.30  ? 189 ASN B CB  1 
ATOM   5054  C CG  . ASN B 1 181 ? -38.465 63.304  16.085 1.00 83.71  ? 189 ASN B CG  1 
ATOM   5055  O OD1 . ASN B 1 181 ? -37.536 63.986  15.570 1.00 52.75  ? 189 ASN B OD1 1 
ATOM   5056  N ND2 . ASN B 1 181 ? -39.784 63.585  16.130 1.00 77.85  ? 189 ASN B ND2 1 
ATOM   5057  N N   . ALA B 1 182 ? -36.592 59.392  17.635 1.00 55.71  ? 190 ALA B N   1 
ATOM   5058  C CA  . ALA B 1 182 ? -36.260 58.490  18.725 1.00 52.51  ? 190 ALA B CA  1 
ATOM   5059  C C   . ALA B 1 182 ? -34.756 58.563  19.018 1.00 50.80  ? 190 ALA B C   1 
ATOM   5060  O O   . ALA B 1 182 ? -34.364 58.580  20.190 1.00 38.90  ? 190 ALA B O   1 
ATOM   5061  C CB  . ALA B 1 182 ? -36.686 57.079  18.409 1.00 79.60  ? 190 ALA B CB  1 
ATOM   5062  N N   . ARG B 1 183 ? -33.929 58.721  17.969 1.00 60.72  ? 191 ARG B N   1 
ATOM   5063  C CA  . ARG B 1 183 ? -32.482 58.781  18.167 1.00 70.63  ? 191 ARG B CA  1 
ATOM   5064  C C   . ARG B 1 183 ? -32.050 60.040  18.916 1.00 73.50  ? 191 ARG B C   1 
ATOM   5065  O O   . ARG B 1 183 ? -31.019 60.002  19.586 1.00 105.94 ? 191 ARG B O   1 
ATOM   5066  C CB  . ARG B 1 183 ? -31.659 58.736  16.874 1.00 72.43  ? 191 ARG B CB  1 
ATOM   5067  C CG  . ARG B 1 183 ? -32.013 57.497  16.073 1.00 77.74  ? 191 ARG B CG  1 
ATOM   5068  C CD  . ARG B 1 183 ? -31.184 57.403  14.804 1.00 87.05  ? 191 ARG B CD  1 
ATOM   5069  N NE  . ARG B 1 183 ? -31.811 57.637  13.497 1.00 95.30  ? 191 ARG B NE  1 
ATOM   5070  C CZ  . ARG B 1 183 ? -32.544 56.678  12.873 1.00 108.45 ? 191 ARG B CZ  1 
ATOM   5071  N NH1 . ARG B 1 183 ? -33.143 57.006  11.722 1.00 76.65  ? 191 ARG B NH1 1 
ATOM   5072  N NH2 . ARG B 1 183 ? -32.746 55.450  13.412 1.00 76.89  ? 191 ARG B NH2 1 
ATOM   5073  N N   . LEU B 1 184 ? -32.826 61.126  18.774 1.00 62.24  ? 192 LEU B N   1 
ATOM   5074  C CA  . LEU B 1 184 ? -32.559 62.403  19.419 1.00 85.28  ? 192 LEU B CA  1 
ATOM   5075  C C   . LEU B 1 184 ? -33.050 62.434  20.867 1.00 90.86  ? 192 LEU B C   1 
ATOM   5076  O O   . LEU B 1 184 ? -32.397 62.996  21.743 1.00 58.70  ? 192 LEU B O   1 
ATOM   5077  C CB  . LEU B 1 184 ? -33.453 63.390  18.670 1.00 68.59  ? 192 LEU B CB  1 
ATOM   5078  C CG  . LEU B 1 184 ? -33.200 63.617  17.192 1.00 60.31  ? 192 LEU B CG  1 
ATOM   5079  C CD1 . LEU B 1 184 ? -34.344 64.568  16.714 1.00 52.49  ? 192 LEU B CD1 1 
ATOM   5080  C CD2 . LEU B 1 184 ? -31.847 64.323  17.247 1.00 67.40  ? 192 LEU B CD2 1 
ATOM   5081  N N   . PHE B 1 185 ? -34.288 61.953  21.048 1.00 96.42  ? 193 PHE B N   1 
ATOM   5082  C CA  . PHE B 1 185 ? -34.998 62.060  22.305 1.00 83.23  ? 193 PHE B CA  1 
ATOM   5083  C C   . PHE B 1 185 ? -34.641 60.942  23.291 1.00 87.93  ? 193 PHE B C   1 
ATOM   5084  O O   . PHE B 1 185 ? -34.788 61.182  24.497 1.00 71.79  ? 193 PHE B O   1 
ATOM   5085  C CB  . PHE B 1 185 ? -36.471 62.005  21.927 1.00 76.06  ? 193 PHE B CB  1 
ATOM   5086  C CG  . PHE B 1 185 ? -37.425 62.238  23.088 1.00 90.98  ? 193 PHE B CG  1 
ATOM   5087  C CD1 . PHE B 1 185 ? -37.468 63.477  23.706 1.00 81.59  ? 193 PHE B CD1 1 
ATOM   5088  C CD2 . PHE B 1 185 ? -38.333 61.260  23.499 1.00 97.17  ? 193 PHE B CD2 1 
ATOM   5089  C CE1 . PHE B 1 185 ? -38.351 63.720  24.743 1.00 84.41  ? 193 PHE B CE1 1 
ATOM   5090  C CE2 . PHE B 1 185 ? -39.204 61.508  24.555 1.00 117.61 ? 193 PHE B CE2 1 
ATOM   5091  C CZ  . PHE B 1 185 ? -39.202 62.729  25.188 1.00 102.29 ? 193 PHE B CZ  1 
ATOM   5092  N N   . HIS B 1 186 ? -34.132 59.774  22.800 1.00 77.87  ? 194 HIS B N   1 
ATOM   5093  C CA  . HIS B 1 186 ? -33.786 58.583  23.589 1.00 67.97  ? 194 HIS B CA  1 
ATOM   5094  C C   . HIS B 1 186 ? -34.975 58.154  24.461 1.00 59.62  ? 194 HIS B C   1 
ATOM   5095  O O   . HIS B 1 186 ? -35.009 58.374  25.686 1.00 75.57  ? 194 HIS B O   1 
ATOM   5096  C CB  . HIS B 1 186 ? -32.546 58.817  24.472 1.00 81.91  ? 194 HIS B CB  1 
ATOM   5097  C CG  . HIS B 1 186 ? -31.494 59.605  23.813 1.00 79.68  ? 194 HIS B CG  1 
ATOM   5098  N ND1 . HIS B 1 186 ? -30.524 58.988  23.082 1.00 115.58 ? 194 HIS B ND1 1 
ATOM   5099  C CD2 . HIS B 1 186 ? -31.366 60.917  23.603 1.00 74.98  ? 194 HIS B CD2 1 
ATOM   5100  C CE1 . HIS B 1 186 ? -29.767 59.922  22.520 1.00 117.43 ? 194 HIS B CE1 1 
ATOM   5101  N NE2 . HIS B 1 186 ? -30.293 61.101  22.790 1.00 84.16  ? 194 HIS B NE2 1 
ATOM   5102  N N   . PRO B 1 187 ? -36.058 57.617  23.871 1.00 58.85  ? 195 PRO B N   1 
ATOM   5103  C CA  . PRO B 1 187 ? -37.258 57.251  24.648 1.00 64.40  ? 195 PRO B CA  1 
ATOM   5104  C C   . PRO B 1 187 ? -36.882 56.040  25.467 1.00 72.99  ? 195 PRO B C   1 
ATOM   5105  O O   . PRO B 1 187 ? -36.065 55.258  24.966 1.00 84.54  ? 195 PRO B O   1 
ATOM   5106  C CB  . PRO B 1 187 ? -38.334 56.875  23.609 1.00 62.06  ? 195 PRO B CB  1 
ATOM   5107  C CG  . PRO B 1 187 ? -37.551 56.578  22.336 1.00 65.50  ? 195 PRO B CG  1 
ATOM   5108  C CD  . PRO B 1 187 ? -36.274 57.449  22.421 1.00 80.24  ? 195 PRO B CD  1 
ATOM   5109  N N   . LYS B 1 188 ? -37.427 55.939  26.700 1.00 71.25  ? 196 LYS B N   1 
ATOM   5110  C CA  . LYS B 1 188 ? -37.208 54.767  27.546 1.00 71.50  ? 196 LYS B CA  1 
ATOM   5111  C C   . LYS B 1 188 ? -38.260 53.731  27.112 1.00 87.85  ? 196 LYS B C   1 
ATOM   5112  O O   . LYS B 1 188 ? -38.025 52.510  27.202 1.00 77.13  ? 196 LYS B O   1 
ATOM   5113  C CB  . LYS B 1 188 ? -37.390 54.993  29.056 1.00 56.47  ? 196 LYS B CB  1 
ATOM   5114  C CG  . LYS B 1 188 ? -36.550 55.754  30.135 1.00 63.41  ? 196 LYS B CG  1 
ATOM   5115  C CD  . LYS B 1 188 ? -35.032 55.877  30.416 1.00 72.64  ? 196 LYS B CD  1 
ATOM   5116  C CE  . LYS B 1 188 ? -33.827 55.178  29.700 1.00 91.00  ? 196 LYS B CE  1 
ATOM   5117  N NZ  . LYS B 1 188 ? -33.296 55.332  28.307 1.00 45.12  ? 196 LYS B NZ  1 
ATOM   5118  N N   . LEU B 1 189 ? -39.404 54.243  26.592 1.00 71.46  ? 197 LEU B N   1 
ATOM   5119  C CA  . LEU B 1 189 ? -40.567 53.438  26.244 1.00 63.27  ? 197 LEU B CA  1 
ATOM   5120  C C   . LEU B 1 189 ? -41.345 54.082  25.093 1.00 74.40  ? 197 LEU B C   1 
ATOM   5121  O O   . LEU B 1 189 ? -41.573 55.285  25.086 1.00 99.78  ? 197 LEU B O   1 
ATOM   5122  C CB  . LEU B 1 189 ? -41.416 53.212  27.493 1.00 59.52  ? 197 LEU B CB  1 
ATOM   5123  C CG  . LEU B 1 189 ? -42.747 52.461  27.320 1.00 86.29  ? 197 LEU B CG  1 
ATOM   5124  C CD1 . LEU B 1 189 ? -43.205 51.833  28.660 1.00 87.43  ? 197 LEU B CD1 1 
ATOM   5125  C CD2 . LEU B 1 189 ? -43.912 53.259  26.727 1.00 78.68  ? 197 LEU B CD2 1 
ATOM   5126  N N   . ILE B 1 190 ? -41.769 53.271  24.114 1.00 74.31  ? 198 ILE B N   1 
ATOM   5127  C CA  . ILE B 1 190 ? -42.520 53.749  22.964 1.00 70.20  ? 198 ILE B CA  1 
ATOM   5128  C C   . ILE B 1 190 ? -43.864 53.028  22.956 1.00 77.08  ? 198 ILE B C   1 
ATOM   5129  O O   . ILE B 1 190 ? -43.920 51.786  22.989 1.00 88.53  ? 198 ILE B O   1 
ATOM   5130  C CB  . ILE B 1 190 ? -41.790 53.461  21.638 1.00 65.09  ? 198 ILE B CB  1 
ATOM   5131  C CG1 . ILE B 1 190 ? -40.415 54.108  21.549 1.00 76.54  ? 198 ILE B CG1 1 
ATOM   5132  C CG2 . ILE B 1 190 ? -42.650 53.816  20.421 1.00 51.01  ? 198 ILE B CG2 1 
ATOM   5133  C CD1 . ILE B 1 190 ? -39.591 53.650  20.343 1.00 60.79  ? 198 ILE B CD1 1 
ATOM   5134  N N   . ILE B 1 191 ? -44.933 53.811  22.809 1.00 58.06  ? 199 ILE B N   1 
ATOM   5135  C CA  . ILE B 1 191 ? -46.278 53.274  22.846 1.00 61.71  ? 199 ILE B CA  1 
ATOM   5136  C C   . ILE B 1 191 ? -46.750 52.949  21.422 1.00 75.15  ? 199 ILE B C   1 
ATOM   5137  O O   . ILE B 1 191 ? -46.700 53.785  20.505 1.00 105.14 ? 199 ILE B O   1 
ATOM   5138  C CB  . ILE B 1 191 ? -47.175 54.306  23.546 1.00 78.08  ? 199 ILE B CB  1 
ATOM   5139  C CG1 . ILE B 1 191 ? -46.695 54.597  24.930 1.00 87.56  ? 199 ILE B CG1 1 
ATOM   5140  C CG2 . ILE B 1 191 ? -48.659 53.947  23.550 1.00 81.60  ? 199 ILE B CG2 1 
ATOM   5141  C CD1 . ILE B 1 191 ? -47.361 55.848  25.500 1.00 84.35  ? 199 ILE B CD1 1 
ATOM   5142  N N   . ALA B 1 192 ? -47.297 51.737  21.269 1.00 71.55  ? 200 ALA B N   1 
ATOM   5143  C CA  . ALA B 1 192 ? -47.890 51.290  20.017 1.00 74.65  ? 200 ALA B CA  1 
ATOM   5144  C C   . ALA B 1 192 ? -49.388 51.099  20.231 1.00 90.87  ? 200 ALA B C   1 
ATOM   5145  O O   . ALA B 1 192 ? -49.847 50.029  20.643 1.00 94.37  ? 200 ALA B O   1 
ATOM   5146  C CB  . ALA B 1 192 ? -47.227 50.001  19.604 1.00 83.85  ? 200 ALA B CB  1 
ATOM   5147  N N   . GLY B 1 193 ? -50.145 52.173  19.999 1.00 93.87  ? 201 GLY B N   1 
ATOM   5148  C CA  . GLY B 1 193 ? -51.554 52.210  20.365 1.00 77.10  ? 201 GLY B CA  1 
ATOM   5149  C C   . GLY B 1 193 ? -52.143 53.537  19.887 1.00 80.80  ? 201 GLY B C   1 
ATOM   5150  O O   . GLY B 1 193 ? -51.427 54.554  19.891 1.00 106.79 ? 201 GLY B O   1 
ATOM   5151  N N   . THR B 1 194 ? -53.423 53.511  19.475 1.00 60.46  ? 202 THR B N   1 
ATOM   5152  C CA  . THR B 1 194 ? -54.114 54.723  19.022 1.00 61.40  ? 202 THR B CA  1 
ATOM   5153  C C   . THR B 1 194 ? -55.527 54.794  19.617 1.00 73.42  ? 202 THR B C   1 
ATOM   5154  O O   . THR B 1 194 ? -56.079 53.804  20.125 1.00 61.13  ? 202 THR B O   1 
ATOM   5155  C CB  . THR B 1 194 ? -54.169 54.832  17.494 1.00 66.25  ? 202 THR B CB  1 
ATOM   5156  O OG1 . THR B 1 194 ? -55.081 53.828  17.051 1.00 73.32  ? 202 THR B OG1 1 
ATOM   5157  C CG2 . THR B 1 194 ? -52.834 54.589  16.811 1.00 70.53  ? 202 THR B CG2 1 
ATOM   5158  N N   . SER B 1 195 ? -56.124 55.991  19.550 1.00 79.82  ? 203 SER B N   1 
ATOM   5159  C CA  . SER B 1 195 ? -57.519 56.155  19.890 1.00 83.85  ? 203 SER B CA  1 
ATOM   5160  C C   . SER B 1 195 ? -58.334 56.412  18.620 1.00 97.70  ? 203 SER B C   1 
ATOM   5161  O O   . SER B 1 195 ? -59.550 56.275  18.637 1.00 115.62 ? 203 SER B O   1 
ATOM   5162  C CB  . SER B 1 195 ? -57.664 57.267  20.853 1.00 88.38  ? 203 SER B CB  1 
ATOM   5163  O OG  . SER B 1 195 ? -57.400 56.793  22.162 1.00 118.55 ? 203 SER B OG  1 
ATOM   5164  N N   . CYS B 1 196 ? -57.667 56.841  17.543 1.00 87.86  ? 204 CYS B N   1 
ATOM   5165  C CA  . CYS B 1 196 ? -58.392 57.098  16.321 1.00 59.96  ? 204 CYS B CA  1 
ATOM   5166  C C   . CYS B 1 196 ? -57.462 56.940  15.122 1.00 59.63  ? 204 CYS B C   1 
ATOM   5167  O O   . CYS B 1 196 ? -56.948 57.940  14.628 1.00 56.60  ? 204 CYS B O   1 
ATOM   5168  C CB  . CYS B 1 196 ? -58.802 58.563  16.309 1.00 71.44  ? 204 CYS B CB  1 
ATOM   5169  S SG  . CYS B 1 196 ? -59.965 58.929  14.966 1.00 104.70 ? 204 CYS B SG  1 
ATOM   5170  N N   . TYR B 1 197 ? -57.234 55.697  14.666 1.00 55.10  ? 205 TYR B N   1 
ATOM   5171  C CA  . TYR B 1 197 ? -56.475 55.432  13.446 1.00 49.92  ? 205 TYR B CA  1 
ATOM   5172  C C   . TYR B 1 197 ? -57.055 54.178  12.780 1.00 70.59  ? 205 TYR B C   1 
ATOM   5173  O O   . TYR B 1 197 ? -57.344 53.181  13.424 1.00 69.77  ? 205 TYR B O   1 
ATOM   5174  C CB  . TYR B 1 197 ? -55.048 55.254  13.943 1.00 46.85  ? 205 TYR B CB  1 
ATOM   5175  C CG  . TYR B 1 197 ? -53.976 55.022  12.898 1.00 57.63  ? 205 TYR B CG  1 
ATOM   5176  C CD1 . TYR B 1 197 ? -53.503 56.088  12.138 1.00 67.57  ? 205 TYR B CD1 1 
ATOM   5177  C CD2 . TYR B 1 197 ? -53.330 53.790  12.764 1.00 64.89  ? 205 TYR B CD2 1 
ATOM   5178  C CE1 . TYR B 1 197 ? -52.467 55.908  11.218 1.00 68.21  ? 205 TYR B CE1 1 
ATOM   5179  C CE2 . TYR B 1 197 ? -52.301 53.586  11.854 1.00 63.50  ? 205 TYR B CE2 1 
ATOM   5180  C CZ  . TYR B 1 197 ? -51.884 54.649  11.074 1.00 72.48  ? 205 TYR B CZ  1 
ATOM   5181  O OH  . TYR B 1 197 ? -50.877 54.392  10.206 1.00 101.83 ? 205 TYR B OH  1 
ATOM   5182  N N   . SER B 1 198 ? -57.329 54.224  11.472 1.00 100.99 ? 206 SER B N   1 
ATOM   5183  C CA  . SER B 1 198 ? -58.128 53.175  10.839 1.00 90.08  ? 206 SER B CA  1 
ATOM   5184  C C   . SER B 1 198 ? -57.249 52.007  10.418 1.00 97.38  ? 206 SER B C   1 
ATOM   5185  O O   . SER B 1 198 ? -57.770 51.042  9.850  1.00 125.93 ? 206 SER B O   1 
ATOM   5186  C CB  . SER B 1 198 ? -58.868 53.666  9.625  1.00 116.97 ? 206 SER B CB  1 
ATOM   5187  O OG  . SER B 1 198 ? -59.470 54.963  9.641  1.00 117.43 ? 206 SER B OG  1 
ATOM   5188  N N   . ARG B 1 199 ? -55.934 52.073  10.700 1.00 92.36  ? 207 ARG B N   1 
ATOM   5189  C CA  . ARG B 1 199 ? -55.000 51.093  10.137 1.00 84.76  ? 207 ARG B CA  1 
ATOM   5190  C C   . ARG B 1 199 ? -54.261 50.326  11.225 1.00 90.11  ? 207 ARG B C   1 
ATOM   5191  O O   . ARG B 1 199 ? -54.243 50.764  12.364 1.00 83.21  ? 207 ARG B O   1 
ATOM   5192  C CB  . ARG B 1 199 ? -53.955 51.727  9.220  1.00 95.91  ? 207 ARG B CB  1 
ATOM   5193  C CG  . ARG B 1 199 ? -54.620 52.401  8.030  1.00 106.82 ? 207 ARG B CG  1 
ATOM   5194  C CD  . ARG B 1 199 ? -55.411 51.379  7.271  1.00 96.99  ? 207 ARG B CD  1 
ATOM   5195  N NE  . ARG B 1 199 ? -56.062 52.065  6.164  1.00 103.35 ? 207 ARG B NE  1 
ATOM   5196  C CZ  . ARG B 1 199 ? -56.796 51.512  5.219  1.00 87.98  ? 207 ARG B CZ  1 
ATOM   5197  N NH1 . ARG B 1 199 ? -57.206 50.259  5.317  1.00 80.97  ? 207 ARG B NH1 1 
ATOM   5198  N NH2 . ARG B 1 199 ? -57.232 52.281  4.243  1.00 76.17  ? 207 ARG B NH2 1 
ATOM   5199  N N   . ASN B 1 200 ? -53.681 49.170  10.865 1.00 91.75  ? 208 ASN B N   1 
ATOM   5200  C CA  . ASN B 1 200 ? -52.916 48.402  11.838 1.00 85.94  ? 208 ASN B CA  1 
ATOM   5201  C C   . ASN B 1 200 ? -51.588 49.091  12.128 1.00 92.02  ? 208 ASN B C   1 
ATOM   5202  O O   . ASN B 1 200 ? -51.115 49.943  11.377 1.00 87.55  ? 208 ASN B O   1 
ATOM   5203  C CB  . ASN B 1 200 ? -52.548 47.021  11.312 1.00 69.17  ? 208 ASN B CB  1 
ATOM   5204  C CG  . ASN B 1 200 ? -53.772 46.212  11.046 1.00 53.56  ? 208 ASN B CG  1 
ATOM   5205  O OD1 . ASN B 1 200 ? -54.623 46.095  11.914 1.00 77.32  ? 208 ASN B OD1 1 
ATOM   5206  N ND2 . ASN B 1 200 ? -53.866 45.643  9.875  1.00 52.11  ? 208 ASN B ND2 1 
ATOM   5207  N N   . LEU B 1 201 ? -51.000 48.763  13.271 1.00 99.63  ? 209 LEU B N   1 
ATOM   5208  C CA  . LEU B 1 201 ? -49.727 49.391  13.572 1.00 112.32 ? 209 LEU B CA  1 
ATOM   5209  C C   . LEU B 1 201 ? -48.597 48.476  13.150 1.00 107.31 ? 209 LEU B C   1 
ATOM   5210  O O   . LEU B 1 201 ? -48.671 47.274  13.412 1.00 111.29 ? 209 LEU B O   1 
ATOM   5211  C CB  . LEU B 1 201 ? -49.643 49.641  15.071 1.00 101.29 ? 209 LEU B CB  1 
ATOM   5212  C CG  . LEU B 1 201 ? -50.720 50.585  15.606 1.00 104.20 ? 209 LEU B CG  1 
ATOM   5213  C CD1 . LEU B 1 201 ? -50.400 50.785  17.063 1.00 137.11 ? 209 LEU B CD1 1 
ATOM   5214  C CD2 . LEU B 1 201 ? -50.796 51.923  14.873 1.00 90.40  ? 209 LEU B CD2 1 
ATOM   5215  N N   . GLU B 1 202 ? -47.555 49.076  12.564 1.00 87.05  ? 210 GLU B N   1 
ATOM   5216  C CA  . GLU B 1 202 ? -46.343 48.340  12.249 1.00 92.67  ? 210 GLU B CA  1 
ATOM   5217  C C   . GLU B 1 202 ? -45.579 47.985  13.524 1.00 85.49  ? 210 GLU B C   1 
ATOM   5218  O O   . GLU B 1 202 ? -44.496 48.498  13.689 1.00 97.82  ? 210 GLU B O   1 
ATOM   5219  C CB  . GLU B 1 202 ? -45.537 49.113  11.196 1.00 69.43  ? 210 GLU B CB  1 
ATOM   5220  C CG  . GLU B 1 202 ? -45.984 48.757  9.777  1.00 72.11  ? 210 GLU B CG  1 
ATOM   5221  C CD  . GLU B 1 202 ? -45.676 49.816  8.770  1.00 81.88  ? 210 GLU B CD  1 
ATOM   5222  O OE1 . GLU B 1 202 ? -44.470 49.986  8.463  1.00 107.47 ? 210 GLU B OE1 1 
ATOM   5223  O OE2 . GLU B 1 202 ? -46.660 50.451  8.324  1.00 65.61  ? 210 GLU B OE2 1 
ATOM   5224  N N   . TYR B 1 203 ? -46.115 47.144  14.419 1.00 68.28  ? 211 TYR B N   1 
ATOM   5225  C CA  . TYR B 1 203 ? -45.394 46.640  15.598 1.00 70.72  ? 211 TYR B CA  1 
ATOM   5226  C C   . TYR B 1 203 ? -43.983 46.152  15.199 1.00 99.49  ? 211 TYR B C   1 
ATOM   5227  O O   . TYR B 1 203 ? -42.972 46.553  15.790 1.00 105.17 ? 211 TYR B O   1 
ATOM   5228  C CB  . TYR B 1 203 ? -46.145 45.522  16.365 1.00 53.28  ? 211 TYR B CB  1 
ATOM   5229  C CG  . TYR B 1 203 ? -47.578 45.897  16.716 1.00 63.73  ? 211 TYR B CG  1 
ATOM   5230  C CD1 . TYR B 1 203 ? -47.820 46.816  17.727 1.00 89.26  ? 211 TYR B CD1 1 
ATOM   5231  C CD2 . TYR B 1 203 ? -48.687 45.391  16.033 1.00 69.25  ? 211 TYR B CD2 1 
ATOM   5232  C CE1 . TYR B 1 203 ? -49.104 47.192  18.091 1.00 77.41  ? 211 TYR B CE1 1 
ATOM   5233  C CE2 . TYR B 1 203 ? -49.975 45.775  16.368 1.00 59.12  ? 211 TYR B CE2 1 
ATOM   5234  C CZ  . TYR B 1 203 ? -50.181 46.676  17.401 1.00 67.43  ? 211 TYR B CZ  1 
ATOM   5235  O OH  . TYR B 1 203 ? -51.422 47.084  17.778 1.00 64.36  ? 211 TYR B OH  1 
ATOM   5236  N N   . ALA B 1 204 ? -43.939 45.244  14.212 1.00 86.50  ? 212 ALA B N   1 
ATOM   5237  C CA  . ALA B 1 204 ? -42.800 44.826  13.428 1.00 73.02  ? 212 ALA B CA  1 
ATOM   5238  C C   . ALA B 1 204 ? -41.653 45.882  13.453 1.00 79.81  ? 212 ALA B C   1 
ATOM   5239  O O   . ALA B 1 204 ? -40.530 45.718  14.020 1.00 62.53  ? 212 ALA B O   1 
ATOM   5240  C CB  . ALA B 1 204 ? -43.488 44.774  12.037 1.00 70.48  ? 212 ALA B CB  1 
ATOM   5241  N N   . ARG B 1 205 ? -41.941 47.000  12.748 1.00 74.96  ? 213 ARG B N   1 
ATOM   5242  C CA  . ARG B 1 205 ? -40.977 48.066  12.518 1.00 73.96  ? 213 ARG B CA  1 
ATOM   5243  C C   . ARG B 1 205 ? -40.706 48.807  13.821 1.00 91.55  ? 213 ARG B C   1 
ATOM   5244  O O   . ARG B 1 205 ? -39.558 49.141  14.126 1.00 83.34  ? 213 ARG B O   1 
ATOM   5245  C CB  . ARG B 1 205 ? -41.552 49.075  11.524 1.00 107.43 ? 213 ARG B CB  1 
ATOM   5246  C CG  . ARG B 1 205 ? -40.679 50.250  11.109 1.00 90.01  ? 213 ARG B CG  1 
ATOM   5247  C CD  . ARG B 1 205 ? -41.279 50.742  9.750  1.00 93.22  ? 213 ARG B CD  1 
ATOM   5248  N NE  . ARG B 1 205 ? -40.719 51.944  9.105  1.00 82.77  ? 213 ARG B NE  1 
ATOM   5249  C CZ  . ARG B 1 205 ? -39.677 52.655  9.564  1.00 90.01  ? 213 ARG B CZ  1 
ATOM   5250  N NH1 . ARG B 1 205 ? -38.976 52.240  10.621 1.00 122.86 ? 213 ARG B NH1 1 
ATOM   5251  N NH2 . ARG B 1 205 ? -39.336 53.785  8.971  1.00 45.20  ? 213 ARG B NH2 1 
ATOM   5252  N N   . LEU B 1 206 ? -41.782 49.050  14.592 1.00 89.00  ? 214 LEU B N   1 
ATOM   5253  C CA  . LEU B 1 206 ? -41.637 49.731  15.870 1.00 84.53  ? 214 LEU B CA  1 
ATOM   5254  C C   . LEU B 1 206 ? -40.666 48.974  16.748 1.00 75.41  ? 214 LEU B C   1 
ATOM   5255  O O   . LEU B 1 206 ? -39.913 49.597  17.472 1.00 71.63  ? 214 LEU B O   1 
ATOM   5256  C CB  . LEU B 1 206 ? -42.953 49.896  16.625 1.00 62.85  ? 214 LEU B CB  1 
ATOM   5257  C CG  . LEU B 1 206 ? -43.932 50.854  15.956 1.00 64.17  ? 214 LEU B CG  1 
ATOM   5258  C CD1 . LEU B 1 206 ? -45.148 50.762  16.899 1.00 57.07  ? 214 LEU B CD1 1 
ATOM   5259  C CD2 . LEU B 1 206 ? -43.329 52.253  15.714 1.00 52.15  ? 214 LEU B CD2 1 
ATOM   5260  N N   . ARG B 1 207 ? -40.692 47.645  16.664 1.00 71.62  ? 215 ARG B N   1 
ATOM   5261  C CA  . ARG B 1 207 ? -39.841 46.891  17.550 1.00 87.41  ? 215 ARG B CA  1 
ATOM   5262  C C   . ARG B 1 207 ? -38.374 47.088  17.183 1.00 109.92 ? 215 ARG B C   1 
ATOM   5263  O O   . ARG B 1 207 ? -37.537 47.257  18.089 1.00 98.89  ? 215 ARG B O   1 
ATOM   5264  C CB  . ARG B 1 207 ? -40.147 45.401  17.629 1.00 73.42  ? 215 ARG B CB  1 
ATOM   5265  C CG  . ARG B 1 207 ? -39.098 44.963  18.649 1.00 67.17  ? 215 ARG B CG  1 
ATOM   5266  C CD  . ARG B 1 207 ? -39.651 44.578  19.944 1.00 81.46  ? 215 ARG B CD  1 
ATOM   5267  N NE  . ARG B 1 207 ? -39.529 43.140  20.200 1.00 82.26  ? 215 ARG B NE  1 
ATOM   5268  C CZ  . ARG B 1 207 ? -38.560 42.674  20.971 1.00 110.00 ? 215 ARG B CZ  1 
ATOM   5269  N NH1 . ARG B 1 207 ? -37.448 43.405  21.169 1.00 82.94  ? 215 ARG B NH1 1 
ATOM   5270  N NH2 . ARG B 1 207 ? -38.683 41.439  21.445 1.00 110.81 ? 215 ARG B NH2 1 
ATOM   5271  N N   . LYS B 1 208 ? -38.090 47.077  15.867 1.00 128.52 ? 216 LYS B N   1 
ATOM   5272  C CA  . LYS B 1 208 ? -36.742 47.357  15.391 1.00 143.13 ? 216 LYS B CA  1 
ATOM   5273  C C   . LYS B 1 208 ? -36.312 48.722  15.964 1.00 126.38 ? 216 LYS B C   1 
ATOM   5274  O O   . LYS B 1 208 ? -35.278 48.845  16.647 1.00 102.33 ? 216 LYS B O   1 
ATOM   5275  C CB  . LYS B 1 208 ? -36.759 46.957  13.903 1.00 143.96 ? 216 LYS B CB  1 
ATOM   5276  C CG  . LYS B 1 208 ? -37.212 45.490  13.504 1.00 129.28 ? 216 LYS B CG  1 
ATOM   5277  C CD  . LYS B 1 208 ? -37.108 45.053  12.025 1.00 110.99 ? 216 LYS B CD  1 
ATOM   5278  C CE  . LYS B 1 208 ? -37.998 43.995  11.389 1.00 88.45  ? 216 LYS B CE  1 
ATOM   5279  N NZ  . LYS B 1 208 ? -38.261 43.905  9.927  1.00 54.37  ? 216 LYS B NZ  1 
ATOM   5280  N N   . ILE B 1 209 ? -37.189 49.733  15.817 1.00 98.04  ? 217 ILE B N   1 
ATOM   5281  C CA  . ILE B 1 209 ? -36.881 51.080  16.278 1.00 89.60  ? 217 ILE B CA  1 
ATOM   5282  C C   . ILE B 1 209 ? -36.577 51.108  17.767 1.00 82.91  ? 217 ILE B C   1 
ATOM   5283  O O   . ILE B 1 209 ? -35.714 51.862  18.183 1.00 76.80  ? 217 ILE B O   1 
ATOM   5284  C CB  . ILE B 1 209 ? -38.001 52.118  16.065 1.00 95.74  ? 217 ILE B CB  1 
ATOM   5285  C CG1 . ILE B 1 209 ? -38.809 51.945  14.784 1.00 73.42  ? 217 ILE B CG1 1 
ATOM   5286  C CG2 . ILE B 1 209 ? -37.450 53.552  16.308 1.00 62.61  ? 217 ILE B CG2 1 
ATOM   5287  C CD1 . ILE B 1 209 ? -39.782 53.083  14.653 1.00 84.76  ? 217 ILE B CD1 1 
ATOM   5288  N N   . ALA B 1 210 ? -37.408 50.414  18.554 1.00 83.76  ? 218 ALA B N   1 
ATOM   5289  C CA  . ALA B 1 210 ? -37.281 50.416  20.001 1.00 84.86  ? 218 ALA B CA  1 
ATOM   5290  C C   . ALA B 1 210 ? -35.944 49.779  20.362 1.00 90.29  ? 218 ALA B C   1 
ATOM   5291  O O   . ALA B 1 210 ? -35.165 50.388  21.097 1.00 60.82  ? 218 ALA B O   1 
ATOM   5292  C CB  . ALA B 1 210 ? -38.461 49.734  20.674 1.00 75.74  ? 218 ALA B CB  1 
ATOM   5293  N N   . ASP B 1 211 ? -35.655 48.605  19.784 1.00 93.44  ? 219 ASP B N   1 
ATOM   5294  C CA  . ASP B 1 211 ? -34.418 47.910  20.095 1.00 87.32  ? 219 ASP B CA  1 
ATOM   5295  C C   . ASP B 1 211 ? -33.247 48.790  19.736 1.00 79.69  ? 219 ASP B C   1 
ATOM   5296  O O   . ASP B 1 211 ? -32.293 48.814  20.487 1.00 115.06 ? 219 ASP B O   1 
ATOM   5297  C CB  . ASP B 1 211 ? -34.311 46.551  19.438 1.00 75.81  ? 219 ASP B CB  1 
ATOM   5298  C CG  . ASP B 1 211 ? -35.366 45.566  19.929 1.00 95.42  ? 219 ASP B CG  1 
ATOM   5299  O OD1 . ASP B 1 211 ? -35.727 45.588  21.118 1.00 106.15 ? 219 ASP B OD1 1 
ATOM   5300  O OD2 . ASP B 1 211 ? -35.800 44.758  19.135 1.00 104.36 ? 219 ASP B OD2 1 
ATOM   5301  N N   . GLU B 1 212 ? -33.353 49.539  18.644 1.00 71.44  ? 220 GLU B N   1 
ATOM   5302  C CA  . GLU B 1 212 ? -32.290 50.458  18.247 1.00 70.88  ? 220 GLU B CA  1 
ATOM   5303  C C   . GLU B 1 212 ? -31.951 51.402  19.400 1.00 58.16  ? 220 GLU B C   1 
ATOM   5304  O O   . GLU B 1 212 ? -30.792 51.759  19.525 1.00 70.27  ? 220 GLU B O   1 
ATOM   5305  C CB  . GLU B 1 212 ? -32.533 51.262  16.958 1.00 63.90  ? 220 GLU B CB  1 
ATOM   5306  C CG  . GLU B 1 212 ? -31.275 51.967  16.463 1.00 60.06  ? 220 GLU B CG  1 
ATOM   5307  C CD  . GLU B 1 212 ? -31.413 53.101  15.473 1.00 93.81  ? 220 GLU B CD  1 
ATOM   5308  O OE1 . GLU B 1 212 ? -32.205 52.958  14.490 1.00 108.32 ? 220 GLU B OE1 1 
ATOM   5309  O OE2 . GLU B 1 212 ? -30.652 54.099  15.665 1.00 70.25  ? 220 GLU B OE2 1 
ATOM   5310  N N   . ASN B 1 213 ? -32.941 51.781  20.219 1.00 65.56  ? 221 ASN B N   1 
ATOM   5311  C CA  . ASN B 1 213 ? -32.765 52.806  21.239 1.00 71.76  ? 221 ASN B CA  1 
ATOM   5312  C C   . ASN B 1 213 ? -32.775 52.209  22.627 1.00 69.12  ? 221 ASN B C   1 
ATOM   5313  O O   . ASN B 1 213 ? -32.632 52.967  23.585 1.00 73.39  ? 221 ASN B O   1 
ATOM   5314  C CB  . ASN B 1 213 ? -33.862 53.856  21.188 1.00 66.19  ? 221 ASN B CB  1 
ATOM   5315  C CG  . ASN B 1 213 ? -33.687 54.730  19.979 1.00 63.98  ? 221 ASN B CG  1 
ATOM   5316  O OD1 . ASN B 1 213 ? -32.850 55.641  20.068 1.00 74.90  ? 221 ASN B OD1 1 
ATOM   5317  N ND2 . ASN B 1 213 ? -34.427 54.432  18.905 1.00 54.51  ? 221 ASN B ND2 1 
ATOM   5318  N N   . GLY B 1 214 ? -32.934 50.874  22.692 1.00 64.08  ? 222 GLY B N   1 
ATOM   5319  C CA  . GLY B 1 214 ? -32.921 50.148  23.948 1.00 63.45  ? 222 GLY B CA  1 
ATOM   5320  C C   . GLY B 1 214 ? -34.160 50.493  24.740 1.00 54.97  ? 222 GLY B C   1 
ATOM   5321  O O   . GLY B 1 214 ? -34.172 50.389  25.949 1.00 63.12  ? 222 GLY B O   1 
ATOM   5322  N N   . ALA B 1 215 ? -35.221 50.895  24.042 1.00 63.15  ? 223 ALA B N   1 
ATOM   5323  C CA  . ALA B 1 215 ? -36.454 51.260  24.732 1.00 55.80  ? 223 ALA B CA  1 
ATOM   5324  C C   . ALA B 1 215 ? -37.405 50.095  24.639 1.00 71.90  ? 223 ALA B C   1 
ATOM   5325  O O   . ALA B 1 215 ? -37.231 49.189  23.815 1.00 70.53  ? 223 ALA B O   1 
ATOM   5326  C CB  . ALA B 1 215 ? -37.144 52.430  24.096 1.00 67.58  ? 223 ALA B CB  1 
ATOM   5327  N N   . TYR B 1 216 ? -38.408 50.168  25.519 1.00 83.05  ? 224 TYR B N   1 
ATOM   5328  C CA  . TYR B 1 216 ? -39.435 49.146  25.587 1.00 83.12  ? 224 TYR B CA  1 
ATOM   5329  C C   . TYR B 1 216 ? -40.501 49.457  24.563 1.00 80.06  ? 224 TYR B C   1 
ATOM   5330  O O   . TYR B 1 216 ? -40.736 50.634  24.293 1.00 122.28 ? 224 TYR B O   1 
ATOM   5331  C CB  . TYR B 1 216 ? -40.126 49.339  26.930 1.00 94.77  ? 224 TYR B CB  1 
ATOM   5332  C CG  . TYR B 1 216 ? -39.406 48.683  28.092 1.00 98.87  ? 224 TYR B CG  1 
ATOM   5333  C CD1 . TYR B 1 216 ? -39.024 47.340  28.086 1.00 100.98 ? 224 TYR B CD1 1 
ATOM   5334  C CD2 . TYR B 1 216 ? -39.113 49.447  29.200 1.00 93.61  ? 224 TYR B CD2 1 
ATOM   5335  C CE1 . TYR B 1 216 ? -38.332 46.813  29.156 1.00 96.28  ? 224 TYR B CE1 1 
ATOM   5336  C CE2 . TYR B 1 216 ? -38.452 48.911  30.291 1.00 97.69  ? 224 TYR B CE2 1 
ATOM   5337  C CZ  . TYR B 1 216 ? -38.047 47.600  30.254 1.00 86.76  ? 224 TYR B CZ  1 
ATOM   5338  O OH  . TYR B 1 216 ? -37.421 47.118  31.356 1.00 111.02 ? 224 TYR B OH  1 
ATOM   5339  N N   . LEU B 1 217 ? -41.144 48.412  24.035 1.00 80.65  ? 225 LEU B N   1 
ATOM   5340  C CA  . LEU B 1 217 ? -42.234 48.649  23.102 1.00 103.29 ? 225 LEU B CA  1 
ATOM   5341  C C   . LEU B 1 217 ? -43.535 48.217  23.757 1.00 99.38  ? 225 LEU B C   1 
ATOM   5342  O O   . LEU B 1 217 ? -43.774 47.039  23.967 1.00 119.34 ? 225 LEU B O   1 
ATOM   5343  C CB  . LEU B 1 217 ? -42.015 47.924  21.776 1.00 93.56  ? 225 LEU B CB  1 
ATOM   5344  C CG  . LEU B 1 217 ? -43.100 48.166  20.741 1.00 89.50  ? 225 LEU B CG  1 
ATOM   5345  C CD1 . LEU B 1 217 ? -42.695 49.547  20.282 1.00 78.84  ? 225 LEU B CD1 1 
ATOM   5346  C CD2 . LEU B 1 217 ? -42.988 47.084  19.650 1.00 105.99 ? 225 LEU B CD2 1 
ATOM   5347  N N   . MET B 1 218 ? -44.313 49.188  24.190 1.00 80.18  ? 226 MET B N   1 
ATOM   5348  C CA  . MET B 1 218 ? -45.518 48.895  24.946 1.00 67.95  ? 226 MET B CA  1 
ATOM   5349  C C   . MET B 1 218 ? -46.714 49.200  24.045 1.00 78.36  ? 226 MET B C   1 
ATOM   5350  O O   . MET B 1 218 ? -46.881 50.301  23.485 1.00 78.54  ? 226 MET B O   1 
ATOM   5351  C CB  . MET B 1 218 ? -45.650 49.781  26.191 1.00 68.34  ? 226 MET B CB  1 
ATOM   5352  C CG  . MET B 1 218 ? -46.941 49.482  26.912 1.00 69.01  ? 226 MET B CG  1 
ATOM   5353  S SD  . MET B 1 218 ? -47.525 50.821  27.965 1.00 77.77  ? 226 MET B SD  1 
ATOM   5354  C CE  . MET B 1 218 ? -48.562 51.319  26.575 1.00 85.20  ? 226 MET B CE  1 
ATOM   5355  N N   . ALA B 1 219 ? -47.563 48.191  23.885 1.00 67.37  ? 227 ALA B N   1 
ATOM   5356  C CA  . ALA B 1 219 ? -48.706 48.349  23.000 1.00 67.73  ? 227 ALA B CA  1 
ATOM   5357  C C   . ALA B 1 219 ? -49.918 48.663  23.858 1.00 83.70  ? 227 ALA B C   1 
ATOM   5358  O O   . ALA B 1 219 ? -50.040 48.092  24.949 1.00 83.12  ? 227 ALA B O   1 
ATOM   5359  C CB  . ALA B 1 219 ? -48.893 47.085  22.217 1.00 67.22  ? 227 ALA B CB  1 
ATOM   5360  N N   . ASP B 1 220 ? -50.744 49.608  23.375 1.00 76.37  ? 228 ASP B N   1 
ATOM   5361  C CA  . ASP B 1 220 ? -52.000 49.927  24.037 1.00 71.50  ? 228 ASP B CA  1 
ATOM   5362  C C   . ASP B 1 220 ? -53.103 49.495  23.080 1.00 66.43  ? 228 ASP B C   1 
ATOM   5363  O O   . ASP B 1 220 ? -53.467 50.232  22.163 1.00 89.49  ? 228 ASP B O   1 
ATOM   5364  C CB  . ASP B 1 220 ? -52.100 51.393  24.447 1.00 66.64  ? 228 ASP B CB  1 
ATOM   5365  C CG  . ASP B 1 220 ? -53.330 51.771  25.270 1.00 79.40  ? 228 ASP B CG  1 
ATOM   5366  O OD1 . ASP B 1 220 ? -54.287 50.997  25.368 1.00 91.01  ? 228 ASP B OD1 1 
ATOM   5367  O OD2 . ASP B 1 220 ? -53.322 52.814  25.898 1.00 86.72  ? 228 ASP B OD2 1 
ATOM   5368  N N   . MET B 1 221 ? -53.635 48.294  23.301 1.00 59.40  ? 229 MET B N   1 
ATOM   5369  C CA  . MET B 1 221 ? -54.562 47.708  22.345 1.00 77.45  ? 229 MET B CA  1 
ATOM   5370  C C   . MET B 1 221 ? -56.005 47.959  22.775 1.00 84.55  ? 229 MET B C   1 
ATOM   5371  O O   . MET B 1 221 ? -56.887 47.260  22.289 1.00 86.28  ? 229 MET B O   1 
ATOM   5372  C CB  . MET B 1 221 ? -54.336 46.196  22.161 1.00 88.76  ? 229 MET B CB  1 
ATOM   5373  C CG  . MET B 1 221 ? -54.599 45.379  23.405 1.00 93.74  ? 229 MET B CG  1 
ATOM   5374  S SD  . MET B 1 221 ? -54.400 43.606  23.206 1.00 84.34  ? 229 MET B SD  1 
ATOM   5375  C CE  . MET B 1 221 ? -55.632 43.421  21.915 1.00 125.32 ? 229 MET B CE  1 
ATOM   5376  N N   . ALA B 1 222 ? -56.238 48.941  23.662 1.00 95.07  ? 230 ALA B N   1 
ATOM   5377  C CA  . ALA B 1 222 ? -57.560 49.213  24.223 1.00 90.29  ? 230 ALA B CA  1 
ATOM   5378  C C   . ALA B 1 222 ? -58.627 49.201  23.148 1.00 86.60  ? 230 ALA B C   1 
ATOM   5379  O O   . ALA B 1 222 ? -59.655 48.533  23.371 1.00 100.96 ? 230 ALA B O   1 
ATOM   5380  C CB  . ALA B 1 222 ? -57.617 50.535  24.939 1.00 99.05  ? 230 ALA B CB  1 
ATOM   5381  N N   . HIS B 1 223 ? -58.363 49.942  22.034 1.00 62.77  ? 231 HIS B N   1 
ATOM   5382  C CA  . HIS B 1 223 ? -59.359 50.095  20.983 1.00 72.35  ? 231 HIS B CA  1 
ATOM   5383  C C   . HIS B 1 223 ? -59.610 48.808  20.192 1.00 76.13  ? 231 HIS B C   1 
ATOM   5384  O O   . HIS B 1 223 ? -60.716 48.602  19.704 1.00 102.00 ? 231 HIS B O   1 
ATOM   5385  C CB  . HIS B 1 223 ? -59.018 51.235  20.024 1.00 81.66  ? 231 HIS B CB  1 
ATOM   5386  C CG  . HIS B 1 223 ? -59.911 52.401  20.161 1.00 93.58  ? 231 HIS B CG  1 
ATOM   5387  N ND1 . HIS B 1 223 ? -59.671 53.435  21.039 1.00 96.59  ? 231 HIS B ND1 1 
ATOM   5388  C CD2 . HIS B 1 223 ? -61.069 52.661  19.547 1.00 101.80 ? 231 HIS B CD2 1 
ATOM   5389  C CE1 . HIS B 1 223 ? -60.653 54.322  20.942 1.00 101.72 ? 231 HIS B CE1 1 
ATOM   5390  N NE2 . HIS B 1 223 ? -61.510 53.869  20.032 1.00 115.75 ? 231 HIS B NE2 1 
ATOM   5391  N N   . ILE B 1 224 ? -58.595 47.946  20.064 1.00 72.46  ? 232 ILE B N   1 
ATOM   5392  C CA  . ILE B 1 224 ? -58.643 46.837  19.122 1.00 78.41  ? 232 ILE B CA  1 
ATOM   5393  C C   . ILE B 1 224 ? -58.474 45.506  19.860 1.00 93.17  ? 232 ILE B C   1 
ATOM   5394  O O   . ILE B 1 224 ? -58.185 44.465  19.233 1.00 112.58 ? 232 ILE B O   1 
ATOM   5395  C CB  . ILE B 1 224 ? -57.552 47.021  18.053 1.00 69.10  ? 232 ILE B CB  1 
ATOM   5396  C CG1 . ILE B 1 224 ? -56.140 46.748  18.634 1.00 50.32  ? 232 ILE B CG1 1 
ATOM   5397  C CG2 . ILE B 1 224 ? -57.651 48.392  17.338 1.00 56.51  ? 232 ILE B CG2 1 
ATOM   5398  C CD1 . ILE B 1 224 ? -55.072 46.574  17.555 1.00 52.92  ? 232 ILE B CD1 1 
ATOM   5399  N N   . SER B 1 225 ? -58.653 45.557  21.196 1.00 87.97  ? 233 SER B N   1 
ATOM   5400  C CA  . SER B 1 225 ? -58.425 44.392  22.043 1.00 96.38  ? 233 SER B CA  1 
ATOM   5401  C C   . SER B 1 225 ? -59.214 43.224  21.507 1.00 87.61  ? 233 SER B C   1 
ATOM   5402  O O   . SER B 1 225 ? -58.634 42.160  21.331 1.00 84.57  ? 233 SER B O   1 
ATOM   5403  C CB  . SER B 1 225 ? -58.711 44.612  23.515 1.00 115.52 ? 233 SER B CB  1 
ATOM   5404  O OG  . SER B 1 225 ? -59.892 45.372  23.716 1.00 109.90 ? 233 SER B OG  1 
ATOM   5405  N N   . GLY B 1 226 ? -60.506 43.451  21.237 1.00 87.02  ? 234 GLY B N   1 
ATOM   5406  C CA  . GLY B 1 226 ? -61.359 42.393  20.729 1.00 101.62 ? 234 GLY B CA  1 
ATOM   5407  C C   . GLY B 1 226 ? -60.916 41.899  19.353 1.00 100.18 ? 234 GLY B C   1 
ATOM   5408  O O   . GLY B 1 226 ? -61.000 40.703  19.074 1.00 90.83  ? 234 GLY B O   1 
ATOM   5409  N N   . LEU B 1 227 ? -60.483 42.827  18.487 1.00 112.55 ? 235 LEU B N   1 
ATOM   5410  C CA  . LEU B 1 227 ? -60.087 42.452  17.142 1.00 117.17 ? 235 LEU B CA  1 
ATOM   5411  C C   . LEU B 1 227 ? -58.914 41.489  17.238 1.00 114.34 ? 235 LEU B C   1 
ATOM   5412  O O   . LEU B 1 227 ? -58.890 40.460  16.562 1.00 102.73 ? 235 LEU B O   1 
ATOM   5413  C CB  . LEU B 1 227 ? -59.682 43.675  16.316 1.00 111.23 ? 235 LEU B CB  1 
ATOM   5414  C CG  . LEU B 1 227 ? -60.763 44.711  16.011 1.00 109.59 ? 235 LEU B CG  1 
ATOM   5415  C CD1 . LEU B 1 227 ? -60.302 45.390  14.725 1.00 140.87 ? 235 LEU B CD1 1 
ATOM   5416  C CD2 . LEU B 1 227 ? -62.141 44.186  15.785 1.00 88.18  ? 235 LEU B CD2 1 
ATOM   5417  N N   . VAL B 1 228 ? -57.974 41.836  18.122 1.00 116.58 ? 236 VAL B N   1 
ATOM   5418  C CA  . VAL B 1 228 ? -56.726 41.104  18.185 1.00 98.82  ? 236 VAL B CA  1 
ATOM   5419  C C   . VAL B 1 228 ? -56.989 39.721  18.759 1.00 85.47  ? 236 VAL B C   1 
ATOM   5420  O O   . VAL B 1 228 ? -56.528 38.734  18.184 1.00 98.61  ? 236 VAL B O   1 
ATOM   5421  C CB  . VAL B 1 228 ? -55.663 41.872  18.982 1.00 89.67  ? 236 VAL B CB  1 
ATOM   5422  C CG1 . VAL B 1 228 ? -54.475 41.014  19.344 1.00 53.52  ? 236 VAL B CG1 1 
ATOM   5423  C CG2 . VAL B 1 228 ? -55.176 43.064  18.200 1.00 104.01 ? 236 VAL B CG2 1 
ATOM   5424  N N   . ALA B 1 229 ? -57.768 39.658  19.846 1.00 74.78  ? 237 ALA B N   1 
ATOM   5425  C CA  . ALA B 1 229 ? -58.112 38.393  20.491 1.00 100.04 ? 237 ALA B CA  1 
ATOM   5426  C C   . ALA B 1 229 ? -58.691 37.394  19.493 1.00 87.02  ? 237 ALA B C   1 
ATOM   5427  O O   . ALA B 1 229 ? -58.328 36.224  19.517 1.00 82.01  ? 237 ALA B O   1 
ATOM   5428  C CB  . ALA B 1 229 ? -59.069 38.613  21.658 1.00 97.17  ? 237 ALA B CB  1 
ATOM   5429  N N   . ALA B 1 230 ? -59.586 37.870  18.611 1.00 95.69  ? 238 ALA B N   1 
ATOM   5430  C CA  . ALA B 1 230 ? -60.258 37.007  17.653 1.00 83.70  ? 238 ALA B CA  1 
ATOM   5431  C C   . ALA B 1 230 ? -59.434 36.847  16.382 1.00 64.51  ? 238 ALA B C   1 
ATOM   5432  O O   . ALA B 1 230 ? -59.913 36.266  15.421 1.00 77.03  ? 238 ALA B O   1 
ATOM   5433  C CB  . ALA B 1 230 ? -61.641 37.552  17.363 1.00 76.43  ? 238 ALA B CB  1 
ATOM   5434  N N   . GLY B 1 231 ? -58.257 37.474  16.334 1.00 70.83  ? 239 GLY B N   1 
ATOM   5435  C CA  . GLY B 1 231 ? -57.292 37.332  15.249 1.00 77.71  ? 239 GLY B CA  1 
ATOM   5436  C C   . GLY B 1 231 ? -57.815 37.879  13.923 1.00 77.06  ? 239 GLY B C   1 
ATOM   5437  O O   . GLY B 1 231 ? -57.546 37.287  12.899 1.00 85.71  ? 239 GLY B O   1 
ATOM   5438  N N   . VAL B 1 232 ? -58.597 38.968  13.961 1.00 82.53  ? 240 VAL B N   1 
ATOM   5439  C CA  . VAL B 1 232 ? -59.099 39.673  12.787 1.00 66.61  ? 240 VAL B CA  1 
ATOM   5440  C C   . VAL B 1 232 ? -58.109 40.792  12.452 1.00 72.12  ? 240 VAL B C   1 
ATOM   5441  O O   . VAL B 1 232 ? -58.254 41.472  11.456 1.00 100.11 ? 240 VAL B O   1 
ATOM   5442  C CB  . VAL B 1 232 ? -60.507 40.207  13.161 1.00 76.24  ? 240 VAL B CB  1 
ATOM   5443  C CG1 . VAL B 1 232 ? -61.163 41.136  12.140 1.00 48.70  ? 240 VAL B CG1 1 
ATOM   5444  C CG2 . VAL B 1 232 ? -61.496 39.117  13.559 1.00 74.60  ? 240 VAL B CG2 1 
ATOM   5445  N N   . VAL B 1 233 ? -57.088 40.999  13.274 1.00 92.73  ? 241 VAL B N   1 
ATOM   5446  C CA  . VAL B 1 233 ? -56.066 42.004  13.022 1.00 89.19  ? 241 VAL B CA  1 
ATOM   5447  C C   . VAL B 1 233 ? -54.752 41.521  13.603 1.00 105.41 ? 241 VAL B C   1 
ATOM   5448  O O   . VAL B 1 233 ? -54.797 40.998  14.719 1.00 125.12 ? 241 VAL B O   1 
ATOM   5449  C CB  . VAL B 1 233 ? -56.418 43.364  13.645 1.00 89.65  ? 241 VAL B CB  1 
ATOM   5450  C CG1 . VAL B 1 233 ? -55.312 43.872  14.598 1.00 72.58  ? 241 VAL B CG1 1 
ATOM   5451  C CG2 . VAL B 1 233 ? -56.688 44.311  12.477 1.00 92.13  ? 241 VAL B CG2 1 
ATOM   5452  N N   . PRO B 1 234 ? -53.593 41.801  12.954 1.00 85.31  ? 242 PRO B N   1 
ATOM   5453  C CA  . PRO B 1 234 ? -52.283 41.339  13.429 1.00 68.44  ? 242 PRO B CA  1 
ATOM   5454  C C   . PRO B 1 234 ? -52.117 41.662  14.903 1.00 73.86  ? 242 PRO B C   1 
ATOM   5455  O O   . PRO B 1 234 ? -52.520 42.754  15.334 1.00 69.92  ? 242 PRO B O   1 
ATOM   5456  C CB  . PRO B 1 234 ? -51.222 42.060  12.579 1.00 69.13  ? 242 PRO B CB  1 
ATOM   5457  C CG  . PRO B 1 234 ? -51.990 42.507  11.372 1.00 77.26  ? 242 PRO B CG  1 
ATOM   5458  C CD  . PRO B 1 234 ? -53.481 42.562  11.704 1.00 99.40  ? 242 PRO B CD  1 
ATOM   5459  N N   . SER B 1 235 ? -51.522 40.704  15.642 1.00 79.42  ? 243 SER B N   1 
ATOM   5460  C CA  . SER B 1 235 ? -51.380 40.835  17.091 1.00 76.59  ? 243 SER B CA  1 
ATOM   5461  C C   . SER B 1 235 ? -50.145 41.644  17.537 1.00 81.71  ? 243 SER B C   1 
ATOM   5462  O O   . SER B 1 235 ? -49.024 41.510  17.016 1.00 105.47 ? 243 SER B O   1 
ATOM   5463  C CB  . SER B 1 235 ? -51.398 39.488  17.722 1.00 74.09  ? 243 SER B CB  1 
ATOM   5464  O OG  . SER B 1 235 ? -50.903 39.579  19.054 1.00 62.24  ? 243 SER B OG  1 
ATOM   5465  N N   . PRO B 1 236 ? -50.296 42.540  18.534 1.00 91.64  ? 244 PRO B N   1 
ATOM   5466  C CA  . PRO B 1 236 ? -49.134 43.240  19.084 1.00 103.59 ? 244 PRO B CA  1 
ATOM   5467  C C   . PRO B 1 236 ? -48.238 42.322  19.901 1.00 115.33 ? 244 PRO B C   1 
ATOM   5468  O O   . PRO B 1 236 ? -47.090 42.677  20.169 1.00 132.46 ? 244 PRO B O   1 
ATOM   5469  C CB  . PRO B 1 236 ? -49.790 44.291  19.955 1.00 73.15  ? 244 PRO B CB  1 
ATOM   5470  C CG  . PRO B 1 236 ? -51.027 43.539  20.491 1.00 65.83  ? 244 PRO B CG  1 
ATOM   5471  C CD  . PRO B 1 236 ? -51.561 42.923  19.191 1.00 70.15  ? 244 PRO B CD  1 
ATOM   5472  N N   . PHE B 1 237 ? -48.793 41.156  20.284 1.00 80.59  ? 245 PHE B N   1 
ATOM   5473  C CA  . PHE B 1 237 ? -48.112 40.288  21.223 1.00 81.91  ? 245 PHE B CA  1 
ATOM   5474  C C   . PHE B 1 237 ? -46.874 39.704  20.583 1.00 70.27  ? 245 PHE B C   1 
ATOM   5475  O O   . PHE B 1 237 ? -46.084 39.074  21.284 1.00 83.72  ? 245 PHE B O   1 
ATOM   5476  C CB  . PHE B 1 237 ? -48.969 39.190  21.828 1.00 66.93  ? 245 PHE B CB  1 
ATOM   5477  C CG  . PHE B 1 237 ? -49.934 39.785  22.821 1.00 78.63  ? 245 PHE B CG  1 
ATOM   5478  C CD1 . PHE B 1 237 ? -49.555 39.975  24.156 1.00 100.85 ? 245 PHE B CD1 1 
ATOM   5479  C CD2 . PHE B 1 237 ? -51.189 40.206  22.399 1.00 87.58  ? 245 PHE B CD2 1 
ATOM   5480  C CE1 . PHE B 1 237 ? -50.464 40.506  25.066 1.00 111.26 ? 245 PHE B CE1 1 
ATOM   5481  C CE2 . PHE B 1 237 ? -52.080 40.752  23.312 1.00 120.29 ? 245 PHE B CE2 1 
ATOM   5482  C CZ  . PHE B 1 237 ? -51.733 40.871  24.638 1.00 110.92 ? 245 PHE B CZ  1 
ATOM   5483  N N   . GLU B 1 238 ? -46.772 39.852  19.268 1.00 60.47  ? 246 GLU B N   1 
ATOM   5484  C CA  . GLU B 1 238 ? -45.701 39.148  18.600 1.00 79.62  ? 246 GLU B CA  1 
ATOM   5485  C C   . GLU B 1 238 ? -44.401 39.939  18.699 1.00 67.46  ? 246 GLU B C   1 
ATOM   5486  O O   . GLU B 1 238 ? -43.343 39.338  18.641 1.00 70.67  ? 246 GLU B O   1 
ATOM   5487  C CB  . GLU B 1 238 ? -46.143 38.880  17.171 1.00 97.49  ? 246 GLU B CB  1 
ATOM   5488  C CG  . GLU B 1 238 ? -45.234 37.856  16.509 1.00 105.56 ? 246 GLU B CG  1 
ATOM   5489  C CD  . GLU B 1 238 ? -45.299 37.854  15.003 1.00 121.22 ? 246 GLU B CD  1 
ATOM   5490  O OE1 . GLU B 1 238 ? -44.428 37.194  14.417 1.00 157.71 ? 246 GLU B OE1 1 
ATOM   5491  O OE2 . GLU B 1 238 ? -46.228 38.444  14.433 1.00 131.04 ? 246 GLU B OE2 1 
ATOM   5492  N N   . HIS B 1 239 ? -44.477 41.271  18.845 1.00 69.25  ? 247 HIS B N   1 
ATOM   5493  C CA  . HIS B 1 239 ? -43.270 42.096  18.854 1.00 63.55  ? 247 HIS B CA  1 
ATOM   5494  C C   . HIS B 1 239 ? -43.119 42.982  20.086 1.00 69.97  ? 247 HIS B C   1 
ATOM   5495  O O   . HIS B 1 239 ? -42.012 43.390  20.356 1.00 61.07  ? 247 HIS B O   1 
ATOM   5496  C CB  . HIS B 1 239 ? -43.222 43.063  17.678 1.00 53.40  ? 247 HIS B CB  1 
ATOM   5497  C CG  . HIS B 1 239 ? -43.518 42.351  16.418 1.00 62.03  ? 247 HIS B CG  1 
ATOM   5498  N ND1 . HIS B 1 239 ? -42.507 41.883  15.610 1.00 51.93  ? 247 HIS B ND1 1 
ATOM   5499  C CD2 . HIS B 1 239 ? -44.673 41.953  15.879 1.00 76.36  ? 247 HIS B CD2 1 
ATOM   5500  C CE1 . HIS B 1 239 ? -43.026 41.264  14.573 1.00 73.67  ? 247 HIS B CE1 1 
ATOM   5501  N NE2 . HIS B 1 239 ? -44.333 41.273  14.729 1.00 107.98 ? 247 HIS B NE2 1 
ATOM   5502  N N   . CYS B 1 240 ? -44.200 43.257  20.832 1.00 72.93  ? 248 CYS B N   1 
ATOM   5503  C CA  . CYS B 1 240 ? -44.141 44.136  21.992 1.00 74.57  ? 248 CYS B CA  1 
ATOM   5504  C C   . CYS B 1 240 ? -43.668 43.437  23.276 1.00 76.93  ? 248 CYS B C   1 
ATOM   5505  O O   . CYS B 1 240 ? -43.881 42.233  23.464 1.00 90.60  ? 248 CYS B O   1 
ATOM   5506  C CB  . CYS B 1 240 ? -45.507 44.768  22.189 1.00 84.59  ? 248 CYS B CB  1 
ATOM   5507  S SG  . CYS B 1 240 ? -45.976 45.754  20.750 1.00 104.52 ? 248 CYS B SG  1 
ATOM   5508  N N   . HIS B 1 241 ? -43.051 44.226  24.176 1.00 67.12  ? 249 HIS B N   1 
ATOM   5509  C CA  . HIS B 1 241 ? -42.567 43.711  25.453 1.00 75.44  ? 249 HIS B CA  1 
ATOM   5510  C C   . HIS B 1 241 ? -43.712 43.638  26.442 1.00 75.40  ? 249 HIS B C   1 
ATOM   5511  O O   . HIS B 1 241 ? -43.765 42.739  27.291 1.00 85.13  ? 249 HIS B O   1 
ATOM   5512  C CB  . HIS B 1 241 ? -41.500 44.617  26.084 1.00 73.63  ? 249 HIS B CB  1 
ATOM   5513  C CG  . HIS B 1 241 ? -40.275 44.656  25.233 1.00 83.84  ? 249 HIS B CG  1 
ATOM   5514  N ND1 . HIS B 1 241 ? -40.017 45.703  24.379 1.00 70.93  ? 249 HIS B ND1 1 
ATOM   5515  C CD2 . HIS B 1 241 ? -39.274 43.753  25.063 1.00 81.56  ? 249 HIS B CD2 1 
ATOM   5516  C CE1 . HIS B 1 241 ? -38.872 45.452  23.758 1.00 96.84  ? 249 HIS B CE1 1 
ATOM   5517  N NE2 . HIS B 1 241 ? -38.414 44.273  24.138 1.00 91.96  ? 249 HIS B NE2 1 
ATOM   5518  N N   . VAL B 1 242 ? -44.587 44.641  26.325 1.00 63.69  ? 250 VAL B N   1 
ATOM   5519  C CA  . VAL B 1 242 ? -45.751 44.739  27.188 1.00 65.56  ? 250 VAL B CA  1 
ATOM   5520  C C   . VAL B 1 242 ? -46.941 45.186  26.345 1.00 85.60  ? 250 VAL B C   1 
ATOM   5521  O O   . VAL B 1 242 ? -46.785 45.981  25.397 1.00 74.75  ? 250 VAL B O   1 
ATOM   5522  C CB  . VAL B 1 242 ? -45.434 45.767  28.277 1.00 59.00  ? 250 VAL B CB  1 
ATOM   5523  C CG1 . VAL B 1 242 ? -46.663 46.271  29.008 1.00 53.27  ? 250 VAL B CG1 1 
ATOM   5524  C CG2 . VAL B 1 242 ? -44.438 45.194  29.254 1.00 64.10  ? 250 VAL B CG2 1 
ATOM   5525  N N   . VAL B 1 243 ? -48.132 44.674  26.719 1.00 74.54  ? 251 VAL B N   1 
ATOM   5526  C CA  . VAL B 1 243 ? -49.356 45.124  26.070 1.00 81.10  ? 251 VAL B CA  1 
ATOM   5527  C C   . VAL B 1 243 ? -50.399 45.449  27.132 1.00 94.11  ? 251 VAL B C   1 
ATOM   5528  O O   . VAL B 1 243 ? -50.745 44.576  27.940 1.00 94.14  ? 251 VAL B O   1 
ATOM   5529  C CB  . VAL B 1 243 ? -49.890 44.055  25.113 1.00 91.77  ? 251 VAL B CB  1 
ATOM   5530  C CG1 . VAL B 1 243 ? -51.201 44.498  24.497 1.00 82.79  ? 251 VAL B CG1 1 
ATOM   5531  C CG2 . VAL B 1 243 ? -48.879 43.686  24.037 1.00 108.33 ? 251 VAL B CG2 1 
ATOM   5532  N N   . THR B 1 244 ? -50.902 46.701  27.104 1.00 74.85  ? 252 THR B N   1 
ATOM   5533  C CA  . THR B 1 244 ? -51.926 47.102  28.059 1.00 72.83  ? 252 THR B CA  1 
ATOM   5534  C C   . THR B 1 244 ? -53.242 47.191  27.311 1.00 81.31  ? 252 THR B C   1 
ATOM   5535  O O   . THR B 1 244 ? -53.235 47.390  26.097 1.00 107.43 ? 252 THR B O   1 
ATOM   5536  C CB  . THR B 1 244 ? -51.585 48.424  28.746 1.00 90.91  ? 252 THR B CB  1 
ATOM   5537  O OG1 . THR B 1 244 ? -51.475 49.411  27.719 1.00 92.35  ? 252 THR B OG1 1 
ATOM   5538  C CG2 . THR B 1 244 ? -50.321 48.340  29.590 1.00 98.68  ? 252 THR B CG2 1 
ATOM   5539  N N   . THR B 1 245 ? -54.358 47.070  28.033 1.00 87.73  ? 253 THR B N   1 
ATOM   5540  C CA  . THR B 1 245 ? -55.649 47.231  27.373 1.00 98.91  ? 253 THR B CA  1 
ATOM   5541  C C   . THR B 1 245 ? -56.778 47.499  28.359 1.00 85.28  ? 253 THR B C   1 
ATOM   5542  O O   . THR B 1 245 ? -56.733 47.114  29.513 1.00 83.75  ? 253 THR B O   1 
ATOM   5543  C CB  . THR B 1 245 ? -55.982 45.967  26.593 1.00 83.07  ? 253 THR B CB  1 
ATOM   5544  O OG1 . THR B 1 245 ? -57.110 46.322  25.806 1.00 84.34  ? 253 THR B OG1 1 
ATOM   5545  C CG2 . THR B 1 245 ? -56.300 44.855  27.563 1.00 82.35  ? 253 THR B CG2 1 
ATOM   5546  N N   . THR B 1 246 ? -57.831 48.105  27.838 1.00 74.96  ? 254 THR B N   1 
ATOM   5547  C CA  . THR B 1 246 ? -59.104 48.224  28.513 1.00 83.31  ? 254 THR B CA  1 
ATOM   5548  C C   . THR B 1 246 ? -59.829 46.878  28.435 1.00 87.34  ? 254 THR B C   1 
ATOM   5549  O O   . THR B 1 246 ? -59.447 46.019  27.666 1.00 79.30  ? 254 THR B O   1 
ATOM   5550  C CB  . THR B 1 246 ? -59.799 49.264  27.654 1.00 87.93  ? 254 THR B CB  1 
ATOM   5551  O OG1 . THR B 1 246 ? -60.756 50.032  28.389 1.00 102.99 ? 254 THR B OG1 1 
ATOM   5552  C CG2 . THR B 1 246 ? -60.259 48.656  26.329 1.00 73.64  ? 254 THR B CG2 1 
ATOM   5553  N N   . THR B 1 247 ? -60.796 46.655  29.307 1.00 79.86  ? 255 THR B N   1 
ATOM   5554  C CA  . THR B 1 247 ? -61.552 45.414  29.271 1.00 80.89  ? 255 THR B CA  1 
ATOM   5555  C C   . THR B 1 247 ? -62.918 45.693  28.665 1.00 82.51  ? 255 THR B C   1 
ATOM   5556  O O   . THR B 1 247 ? -63.631 44.739  28.366 1.00 70.35  ? 255 THR B O   1 
ATOM   5557  C CB  . THR B 1 247 ? -61.654 44.756  30.649 1.00 95.29  ? 255 THR B CB  1 
ATOM   5558  O OG1 . THR B 1 247 ? -62.196 45.706  31.569 1.00 107.88 ? 255 THR B OG1 1 
ATOM   5559  C CG2 . THR B 1 247 ? -60.315 44.224  31.128 1.00 92.44  ? 255 THR B CG2 1 
ATOM   5560  N N   . HIS B 1 248 ? -63.279 46.973  28.495 1.00 75.05  ? 256 HIS B N   1 
ATOM   5561  C CA  . HIS B 1 248 ? -64.441 47.320  27.676 1.00 99.54  ? 256 HIS B CA  1 
ATOM   5562  C C   . HIS B 1 248 ? -64.065 47.565  26.202 1.00 116.79 ? 256 HIS B C   1 
ATOM   5563  O O   . HIS B 1 248 ? -63.150 46.917  25.633 1.00 68.72  ? 256 HIS B O   1 
ATOM   5564  C CB  . HIS B 1 248 ? -65.172 48.496  28.308 1.00 80.23  ? 256 HIS B CB  1 
ATOM   5565  C CG  . HIS B 1 248 ? -64.301 49.633  28.742 1.00 79.38  ? 256 HIS B CG  1 
ATOM   5566  N ND1 . HIS B 1 248 ? -63.607 49.666  29.934 1.00 62.81  ? 256 HIS B ND1 1 
ATOM   5567  C CD2 . HIS B 1 248 ? -64.059 50.824  28.139 1.00 85.14  ? 256 HIS B CD2 1 
ATOM   5568  C CE1 . HIS B 1 248 ? -63.013 50.852  30.062 1.00 77.47  ? 256 HIS B CE1 1 
ATOM   5569  N NE2 . HIS B 1 248 ? -63.231 51.556  28.966 1.00 77.65  ? 256 HIS B NE2 1 
ATOM   5570  N N   . LYS B 1 249 ? -64.770 48.533  25.580 1.00 94.11  ? 257 LYS B N   1 
ATOM   5571  C CA  . LYS B 1 249 ? -64.600 48.750  24.146 1.00 124.19 ? 257 LYS B CA  1 
ATOM   5572  C C   . LYS B 1 249 ? -64.821 47.442  23.370 1.00 117.20 ? 257 LYS B C   1 
ATOM   5573  O O   . LYS B 1 249 ? -65.795 46.731  23.623 1.00 124.73 ? 257 LYS B O   1 
ATOM   5574  C CB  . LYS B 1 249 ? -63.247 49.427  23.893 1.00 115.83 ? 257 LYS B CB  1 
ATOM   5575  C CG  . LYS B 1 249 ? -63.120 50.693  24.726 1.00 103.84 ? 257 LYS B CG  1 
ATOM   5576  C CD  . LYS B 1 249 ? -61.822 51.451  24.497 1.00 125.11 ? 257 LYS B CD  1 
ATOM   5577  C CE  . LYS B 1 249 ? -61.761 52.708  25.283 1.00 116.98 ? 257 LYS B CE  1 
ATOM   5578  N NZ  . LYS B 1 249 ? -60.411 53.251  25.139 1.00 80.68  ? 257 LYS B NZ  1 
ATOM   5579  N N   . THR B 1 250 ? -63.927 47.126  22.420 1.00 103.77 ? 258 THR B N   1 
ATOM   5580  C CA  . THR B 1 250 ? -64.090 45.927  21.596 1.00 104.35 ? 258 THR B CA  1 
ATOM   5581  C C   . THR B 1 250 ? -63.993 44.603  22.382 1.00 96.53  ? 258 THR B C   1 
ATOM   5582  O O   . THR B 1 250 ? -64.251 43.533  21.838 1.00 63.96  ? 258 THR B O   1 
ATOM   5583  C CB  . THR B 1 250 ? -63.148 45.911  20.387 1.00 92.57  ? 258 THR B CB  1 
ATOM   5584  O OG1 . THR B 1 250 ? -61.804 46.193  20.810 1.00 57.77  ? 258 THR B OG1 1 
ATOM   5585  C CG2 . THR B 1 250 ? -63.726 46.602  19.161 1.00 93.60  ? 258 THR B CG2 1 
ATOM   5586  N N   . LEU B 1 251 ? -63.568 44.645  23.644 1.00 104.82 ? 259 LEU B N   1 
ATOM   5587  C CA  . LEU B 1 251 ? -63.470 43.420  24.424 1.00 100.49 ? 259 LEU B CA  1 
ATOM   5588  C C   . LEU B 1 251 ? -64.798 43.145  25.123 1.00 107.31 ? 259 LEU B C   1 
ATOM   5589  O O   . LEU B 1 251 ? -64.985 42.045  25.661 1.00 97.45  ? 259 LEU B O   1 
ATOM   5590  C CB  . LEU B 1 251 ? -62.313 43.496  25.415 1.00 79.83  ? 259 LEU B CB  1 
ATOM   5591  C CG  . LEU B 1 251 ? -61.755 42.160  25.896 1.00 86.08  ? 259 LEU B CG  1 
ATOM   5592  C CD1 . LEU B 1 251 ? -61.228 41.417  24.722 1.00 88.86  ? 259 LEU B CD1 1 
ATOM   5593  C CD2 . LEU B 1 251 ? -60.608 42.418  26.832 1.00 129.07 ? 259 LEU B CD2 1 
ATOM   5594  N N   . ARG B 1 252 ? -65.679 44.169  25.093 1.00 98.49  ? 260 ARG B N   1 
ATOM   5595  C CA  . ARG B 1 252 ? -67.090 44.082  25.471 1.00 120.45 ? 260 ARG B CA  1 
ATOM   5596  C C   . ARG B 1 252 ? -67.288 43.605  26.914 1.00 139.47 ? 260 ARG B C   1 
ATOM   5597  O O   . ARG B 1 252 ? -68.287 42.940  27.246 1.00 140.85 ? 260 ARG B O   1 
ATOM   5598  C CB  . ARG B 1 252 ? -67.895 43.127  24.576 1.00 143.58 ? 260 ARG B CB  1 
ATOM   5599  C CG  . ARG B 1 252 ? -68.362 43.535  23.181 1.00 144.30 ? 260 ARG B CG  1 
ATOM   5600  C CD  . ARG B 1 252 ? -69.807 43.128  23.011 1.00 134.76 ? 260 ARG B CD  1 
ATOM   5601  N NE  . ARG B 1 252 ? -69.899 41.667  23.082 1.00 148.16 ? 260 ARG B NE  1 
ATOM   5602  C CZ  . ARG B 1 252 ? -70.121 40.892  22.035 1.00 124.91 ? 260 ARG B CZ  1 
ATOM   5603  N NH1 . ARG B 1 252 ? -70.413 41.424  20.840 1.00 88.11  ? 260 ARG B NH1 1 
ATOM   5604  N NH2 . ARG B 1 252 ? -70.021 39.582  22.222 1.00 112.85 ? 260 ARG B NH2 1 
ATOM   5605  N N   . GLY B 1 253 ? -66.343 43.966  27.783 1.00 127.09 ? 261 GLY B N   1 
ATOM   5606  C CA  . GLY B 1 253 ? -66.486 43.665  29.200 1.00 90.84  ? 261 GLY B CA  1 
ATOM   5607  C C   . GLY B 1 253 ? -66.847 44.943  29.944 1.00 90.42  ? 261 GLY B C   1 
ATOM   5608  O O   . GLY B 1 253 ? -67.169 45.957  29.317 1.00 106.08 ? 261 GLY B O   1 
ATOM   5609  N N   . CYS B 1 254 ? -66.833 44.862  31.274 1.00 74.78  ? 262 CYS B N   1 
ATOM   5610  C CA  . CYS B 1 254 ? -67.062 46.024  32.123 1.00 62.27  ? 262 CYS B CA  1 
ATOM   5611  C C   . CYS B 1 254 ? -65.795 46.883  32.110 1.00 79.64  ? 262 CYS B C   1 
ATOM   5612  O O   . CYS B 1 254 ? -64.738 46.458  31.629 1.00 68.49  ? 262 CYS B O   1 
ATOM   5613  C CB  . CYS B 1 254 ? -67.447 45.595  33.530 1.00 57.81  ? 262 CYS B CB  1 
ATOM   5614  S SG  . CYS B 1 254 ? -66.198 44.505  34.274 1.00 102.93 ? 262 CYS B SG  1 
ATOM   5615  N N   . ARG B 1 255 ? -65.911 48.087  32.676 1.00 89.13  ? 263 ARG B N   1 
ATOM   5616  C CA  . ARG B 1 255 ? -64.787 49.008  32.660 1.00 99.24  ? 263 ARG B CA  1 
ATOM   5617  C C   . ARG B 1 255 ? -63.746 48.580  33.688 1.00 99.29  ? 263 ARG B C   1 
ATOM   5618  O O   . ARG B 1 255 ? -64.062 48.545  34.879 1.00 119.21 ? 263 ARG B O   1 
ATOM   5619  C CB  . ARG B 1 255 ? -65.310 50.422  32.915 1.00 112.32 ? 263 ARG B CB  1 
ATOM   5620  C CG  . ARG B 1 255 ? -66.105 50.990  31.748 1.00 102.85 ? 263 ARG B CG  1 
ATOM   5621  C CD  . ARG B 1 255 ? -66.859 52.250  32.128 1.00 140.53 ? 263 ARG B CD  1 
ATOM   5622  N NE  . ARG B 1 255 ? -66.988 53.158  30.990 1.00 132.17 ? 263 ARG B NE  1 
ATOM   5623  C CZ  . ARG B 1 255 ? -65.954 53.848  30.524 1.00 134.59 ? 263 ARG B CZ  1 
ATOM   5624  N NH1 . ARG B 1 255 ? -64.692 53.667  31.002 1.00 83.68  ? 263 ARG B NH1 1 
ATOM   5625  N NH2 . ARG B 1 255 ? -66.256 54.726  29.577 1.00 103.17 ? 263 ARG B NH2 1 
ATOM   5626  N N   . ALA B 1 256 ? -62.545 48.239  33.177 1.00 88.99  ? 264 ALA B N   1 
ATOM   5627  C CA  . ALA B 1 256 ? -61.331 47.859  33.909 1.00 101.14 ? 264 ALA B CA  1 
ATOM   5628  C C   . ALA B 1 256 ? -60.176 47.733  32.904 1.00 95.88  ? 264 ALA B C   1 
ATOM   5629  O O   . ALA B 1 256 ? -60.371 47.880  31.700 1.00 87.41  ? 264 ALA B O   1 
ATOM   5630  C CB  . ALA B 1 256 ? -61.524 46.561  34.713 1.00 105.56 ? 264 ALA B CB  1 
ATOM   5631  N N   . GLY B 1 257 ? -58.965 47.416  33.364 1.00 90.02  ? 265 GLY B N   1 
ATOM   5632  C CA  . GLY B 1 257 ? -57.827 47.275  32.466 1.00 65.09  ? 265 GLY B CA  1 
ATOM   5633  C C   . GLY B 1 257 ? -56.923 46.102  32.875 1.00 66.97  ? 265 GLY B C   1 
ATOM   5634  O O   . GLY B 1 257 ? -57.061 45.516  33.958 1.00 65.62  ? 265 GLY B O   1 
ATOM   5635  N N   . MET B 1 258 ? -55.976 45.769  31.996 1.00 50.02  ? 266 MET B N   1 
ATOM   5636  C CA  . MET B 1 258 ? -55.119 44.623  32.209 1.00 54.41  ? 266 MET B CA  1 
ATOM   5637  C C   . MET B 1 258 ? -53.771 44.945  31.597 1.00 61.27  ? 266 MET B C   1 
ATOM   5638  O O   . MET B 1 258 ? -53.709 45.616  30.562 1.00 56.18  ? 266 MET B O   1 
ATOM   5639  C CB  . MET B 1 258 ? -55.647 43.386  31.465 1.00 54.52  ? 266 MET B CB  1 
ATOM   5640  C CG  . MET B 1 258 ? -56.896 42.788  32.059 1.00 58.28  ? 266 MET B CG  1 
ATOM   5641  S SD  . MET B 1 258 ? -57.196 41.421  30.923 1.00 90.20  ? 266 MET B SD  1 
ATOM   5642  C CE  . MET B 1 258 ? -57.146 42.325  29.379 1.00 76.15  ? 266 MET B CE  1 
ATOM   5643  N N   . ILE B 1 259 ? -52.705 44.387  32.198 1.00 65.17  ? 267 ILE B N   1 
ATOM   5644  C CA  . ILE B 1 259 ? -51.361 44.591  31.669 1.00 70.99  ? 267 ILE B CA  1 
ATOM   5645  C C   . ILE B 1 259 ? -50.773 43.217  31.399 1.00 70.03  ? 267 ILE B C   1 
ATOM   5646  O O   . ILE B 1 259 ? -50.550 42.469  32.356 1.00 67.15  ? 267 ILE B O   1 
ATOM   5647  C CB  . ILE B 1 259 ? -50.496 45.391  32.675 1.00 72.82  ? 267 ILE B CB  1 
ATOM   5648  C CG1 . ILE B 1 259 ? -51.091 46.776  32.996 1.00 64.26  ? 267 ILE B CG1 1 
ATOM   5649  C CG2 . ILE B 1 259 ? -49.033 45.493  32.245 1.00 47.41  ? 267 ILE B CG2 1 
ATOM   5650  C CD1 . ILE B 1 259 ? -50.632 47.361  34.322 1.00 42.75  ? 267 ILE B CD1 1 
ATOM   5651  N N   . PHE B 1 260 ? -50.519 42.930  30.105 1.00 58.97  ? 268 PHE B N   1 
ATOM   5652  C CA  . PHE B 1 260 ? -49.753 41.742  29.740 1.00 70.62  ? 268 PHE B CA  1 
ATOM   5653  C C   . PHE B 1 260 ? -48.262 42.109  29.643 1.00 73.06  ? 268 PHE B C   1 
ATOM   5654  O O   . PHE B 1 260 ? -47.912 43.184  29.127 1.00 59.08  ? 268 PHE B O   1 
ATOM   5655  C CB  . PHE B 1 260 ? -50.213 41.240  28.377 1.00 68.16  ? 268 PHE B CB  1 
ATOM   5656  C CG  . PHE B 1 260 ? -51.681 40.840  28.321 1.00 71.22  ? 268 PHE B CG  1 
ATOM   5657  C CD1 . PHE B 1 260 ? -52.688 41.781  28.132 1.00 77.52  ? 268 PHE B CD1 1 
ATOM   5658  C CD2 . PHE B 1 260 ? -52.058 39.505  28.472 1.00 70.57  ? 268 PHE B CD2 1 
ATOM   5659  C CE1 . PHE B 1 260 ? -54.022 41.393  28.145 1.00 81.85  ? 268 PHE B CE1 1 
ATOM   5660  C CE2 . PHE B 1 260 ? -53.387 39.099  28.397 1.00 61.56  ? 268 PHE B CE2 1 
ATOM   5661  C CZ  . PHE B 1 260 ? -54.377 40.054  28.244 1.00 70.95  ? 268 PHE B CZ  1 
ATOM   5662  N N   . TYR B 1 261 ? -47.376 41.210  30.120 1.00 48.85  ? 269 TYR B N   1 
ATOM   5663  C CA  . TYR B 1 261 ? -45.952 41.508  30.133 1.00 59.95  ? 269 TYR B CA  1 
ATOM   5664  C C   . TYR B 1 261 ? -45.147 40.248  29.861 1.00 74.84  ? 269 TYR B C   1 
ATOM   5665  O O   . TYR B 1 261 ? -45.601 39.135  30.169 1.00 92.97  ? 269 TYR B O   1 
ATOM   5666  C CB  . TYR B 1 261 ? -45.551 42.035  31.511 1.00 68.70  ? 269 TYR B CB  1 
ATOM   5667  C CG  . TYR B 1 261 ? -46.140 41.247  32.670 1.00 69.22  ? 269 TYR B CG  1 
ATOM   5668  C CD1 . TYR B 1 261 ? -45.536 40.083  33.137 1.00 69.06  ? 269 TYR B CD1 1 
ATOM   5669  C CD2 . TYR B 1 261 ? -47.293 41.664  33.289 1.00 74.69  ? 269 TYR B CD2 1 
ATOM   5670  C CE1 . TYR B 1 261 ? -46.052 39.358  34.202 1.00 68.59  ? 269 TYR B CE1 1 
ATOM   5671  C CE2 . TYR B 1 261 ? -47.815 40.949  34.360 1.00 92.79  ? 269 TYR B CE2 1 
ATOM   5672  C CZ  . TYR B 1 261 ? -47.209 39.790  34.813 1.00 82.26  ? 269 TYR B CZ  1 
ATOM   5673  O OH  . TYR B 1 261 ? -47.754 39.091  35.845 1.00 100.42 ? 269 TYR B OH  1 
ATOM   5674  N N   . ARG B 1 262 ? -43.925 40.438  29.331 1.00 70.64  ? 270 ARG B N   1 
ATOM   5675  C CA  . ARG B 1 262 ? -43.097 39.294  28.948 1.00 74.40  ? 270 ARG B CA  1 
ATOM   5676  C C   . ARG B 1 262 ? -42.537 38.618  30.220 1.00 64.50  ? 270 ARG B C   1 
ATOM   5677  O O   . ARG B 1 262 ? -42.161 39.292  31.178 1.00 65.61  ? 270 ARG B O   1 
ATOM   5678  C CB  . ARG B 1 262 ? -42.340 39.693  27.657 1.00 71.17  ? 270 ARG B CB  1 
ATOM   5679  C CG  . ARG B 1 262 ? -42.462 38.894  26.353 1.00 73.67  ? 270 ARG B CG  1 
ATOM   5680  C CD  . ARG B 1 262 ? -41.911 39.647  25.162 1.00 71.61  ? 270 ARG B CD  1 
ATOM   5681  N NE  . ARG B 1 262 ? -42.660 39.664  23.894 1.00 74.24  ? 270 ARG B NE  1 
ATOM   5682  C CZ  . ARG B 1 262 ? -42.125 39.826  22.623 1.00 75.83  ? 270 ARG B CZ  1 
ATOM   5683  N NH1 . ARG B 1 262 ? -40.797 39.961  22.366 1.00 54.11  ? 270 ARG B NH1 1 
ATOM   5684  N NH2 . ARG B 1 262 ? -42.927 39.854  21.556 1.00 47.92  ? 270 ARG B NH2 1 
ATOM   5685  N N   . LYS B 1 263 ? -42.583 37.273  30.270 1.00 64.87  ? 271 LYS B N   1 
ATOM   5686  C CA  . LYS B 1 263 ? -41.858 36.425  31.203 1.00 81.45  ? 271 LYS B CA  1 
ATOM   5687  C C   . LYS B 1 263 ? -40.852 35.590  30.401 1.00 100.39 ? 271 LYS B C   1 
ATOM   5688  O O   . LYS B 1 263 ? -41.103 35.293  29.236 1.00 122.14 ? 271 LYS B O   1 
ATOM   5689  C CB  . LYS B 1 263 ? -42.812 35.433  31.874 1.00 57.05  ? 271 LYS B CB  1 
ATOM   5690  C CG  . LYS B 1 263 ? -43.253 35.949  33.266 1.00 69.30  ? 271 LYS B CG  1 
ATOM   5691  C CD  . LYS B 1 263 ? -43.571 35.178  34.560 1.00 77.27  ? 271 LYS B CD  1 
ATOM   5692  C CE  . LYS B 1 263 ? -44.364 33.883  34.865 1.00 68.32  ? 271 LYS B CE  1 
ATOM   5693  N NZ  . LYS B 1 263 ? -45.613 33.699  34.134 1.00 87.45  ? 271 LYS B NZ  1 
ATOM   5694  N N   . GLY B 1 264 ? -39.723 35.219  31.011 1.00 102.11 ? 272 GLY B N   1 
ATOM   5695  C CA  . GLY B 1 264 ? -38.778 34.349  30.316 1.00 74.35  ? 272 GLY B CA  1 
ATOM   5696  C C   . GLY B 1 264 ? -37.461 35.060  30.025 1.00 84.77  ? 272 GLY B C   1 
ATOM   5697  O O   . GLY B 1 264 ? -36.990 35.805  30.860 1.00 109.53 ? 272 GLY B O   1 
ATOM   5698  N N   . VAL B 1 265 ? -36.927 34.896  28.806 1.00 108.71 ? 273 VAL B N   1 
ATOM   5699  C CA  . VAL B 1 265 ? -35.544 35.259  28.542 1.00 101.64 ? 273 VAL B CA  1 
ATOM   5700  C C   . VAL B 1 265 ? -35.459 36.568  27.757 1.00 110.40 ? 273 VAL B C   1 
ATOM   5701  O O   . VAL B 1 265 ? -36.047 36.679  26.676 1.00 88.22  ? 273 VAL B O   1 
ATOM   5702  C CB  . VAL B 1 265 ? -34.827 34.124  27.797 1.00 87.27  ? 273 VAL B CB  1 
ATOM   5703  C CG1 . VAL B 1 265 ? -33.323 34.422  27.711 1.00 88.81  ? 273 VAL B CG1 1 
ATOM   5704  C CG2 . VAL B 1 265 ? -35.206 32.764  28.415 1.00 61.13  ? 273 VAL B CG2 1 
ATOM   5705  N N   . LYS B 1 266 ? -34.768 37.562  28.340 1.00 113.97 ? 274 LYS B N   1 
ATOM   5706  C CA  . LYS B 1 266 ? -34.693 38.893  27.743 1.00 125.40 ? 274 LYS B CA  1 
ATOM   5707  C C   . LYS B 1 266 ? -33.586 38.814  26.704 1.00 128.72 ? 274 LYS B C   1 
ATOM   5708  O O   . LYS B 1 266 ? -33.647 39.458  25.665 1.00 170.30 ? 274 LYS B O   1 
ATOM   5709  C CB  . LYS B 1 266 ? -34.544 40.071  28.728 1.00 122.83 ? 274 LYS B CB  1 
ATOM   5710  C CG  . LYS B 1 266 ? -34.838 41.526  28.254 1.00 88.12  ? 274 LYS B CG  1 
ATOM   5711  C CD  . LYS B 1 266 ? -33.844 42.619  28.703 1.00 94.05  ? 274 LYS B CD  1 
ATOM   5712  C CE  . LYS B 1 266 ? -32.404 42.701  28.125 1.00 90.30  ? 274 LYS B CE  1 
ATOM   5713  N NZ  . LYS B 1 266 ? -31.311 43.227  28.977 1.00 53.90  ? 274 LYS B NZ  1 
ATOM   5714  N N   . SER B 1 267 ? -32.578 38.003  27.030 1.00 108.54 ? 275 SER B N   1 
ATOM   5715  C CA  . SER B 1 267 ? -31.417 37.834  26.128 1.00 135.07 ? 275 SER B CA  1 
ATOM   5716  C C   . SER B 1 267 ? -30.384 36.963  26.839 1.00 133.60 ? 275 SER B C   1 
ATOM   5717  O O   . SER B 1 267 ? -30.573 36.688  28.036 1.00 114.55 ? 275 SER B O   1 
ATOM   5718  C CB  . SER B 1 267 ? -30.830 39.158  25.768 1.00 128.82 ? 275 SER B CB  1 
ATOM   5719  O OG  . SER B 1 267 ? -30.318 39.807  26.920 1.00 124.11 ? 275 SER B OG  1 
ATOM   5720  N N   . VAL B 1 268 ? -29.338 36.551  26.125 1.00 150.89 ? 276 VAL B N   1 
ATOM   5721  C CA  . VAL B 1 268 ? -28.244 35.755  26.747 1.00 137.73 ? 276 VAL B CA  1 
ATOM   5722  C C   . VAL B 1 268 ? -27.105 36.720  27.060 1.00 138.33 ? 276 VAL B C   1 
ATOM   5723  O O   . VAL B 1 268 ? -26.450 37.184  26.111 1.00 140.24 ? 276 VAL B O   1 
ATOM   5724  C CB  . VAL B 1 268 ? -27.778 34.627  25.813 1.00 124.70 ? 276 VAL B CB  1 
ATOM   5725  C CG1 . VAL B 1 268 ? -26.572 33.892  26.375 1.00 122.17 ? 276 VAL B CG1 1 
ATOM   5726  C CG2 . VAL B 1 268 ? -28.904 33.656  25.501 1.00 90.40  ? 276 VAL B CG2 1 
ATOM   5727  N N   . ASP B 1 269 ? -26.885 37.009  28.341 1.00 150.42 ? 277 ASP B N   1 
ATOM   5728  C CA  . ASP B 1 269 ? -25.854 38.009  28.722 1.00 182.35 ? 277 ASP B CA  1 
ATOM   5729  C C   . ASP B 1 269 ? -24.566 37.721  27.958 1.00 226.19 ? 277 ASP B C   1 
ATOM   5730  O O   . ASP B 1 269 ? -24.026 36.613  28.110 1.00 249.51 ? 277 ASP B O   1 
ATOM   5731  C CB  . ASP B 1 269 ? -25.592 37.996  30.228 1.00 155.81 ? 277 ASP B CB  1 
ATOM   5732  C CG  . ASP B 1 269 ? -24.543 38.998  30.669 1.00 144.89 ? 277 ASP B CG  1 
ATOM   5733  O OD1 . ASP B 1 269 ? -24.261 39.927  29.890 1.00 153.46 ? 277 ASP B OD1 1 
ATOM   5734  O OD2 . ASP B 1 269 ? -24.017 38.837  31.785 1.00 132.09 ? 277 ASP B OD2 1 
ATOM   5735  N N   . PRO B 1 270 ? -24.047 38.665  27.148 1.00 205.57 ? 278 PRO B N   1 
ATOM   5736  C CA  . PRO B 1 270 ? -22.766 38.463  26.487 1.00 172.20 ? 278 PRO B CA  1 
ATOM   5737  C C   . PRO B 1 270 ? -21.672 38.534  27.555 1.00 176.83 ? 278 PRO B C   1 
ATOM   5738  O O   . PRO B 1 270 ? -20.586 38.053  27.305 1.00 165.63 ? 278 PRO B O   1 
ATOM   5739  C CB  . PRO B 1 270 ? -22.663 39.667  25.546 1.00 30.00  ? 278 PRO B CB  1 
ATOM   5740  C CG  . PRO B 1 270 ? -23.517 40.726  26.206 1.00 30.00  ? 278 PRO B CG  1 
ATOM   5741  C CD  . PRO B 1 270 ? -24.659 39.956  26.836 1.00 30.00  ? 278 PRO B CD  1 
ATOM   5742  N N   . ALA B 1 271 ? -21.985 39.122  28.711 1.00 174.34 ? 279 ALA B N   1 
ATOM   5743  C CA  . ALA B 1 271 ? -20.955 39.309  29.756 1.00 134.93 ? 279 ALA B CA  1 
ATOM   5744  C C   . ALA B 1 271 ? -20.598 37.973  30.409 1.00 115.72 ? 279 ALA B C   1 
ATOM   5745  O O   . ALA B 1 271 ? -19.397 37.676  30.499 1.00 126.88 ? 279 ALA B O   1 
ATOM   5746  C CB  . ALA B 1 271 ? -21.431 40.306  30.802 1.00 30.00  ? 279 ALA B CB  1 
ATOM   5747  N N   . THR B 1 272 ? -21.594 37.205  30.852 1.00 115.55 ? 280 THR B N   1 
ATOM   5748  C CA  . THR B 1 272 ? -21.297 35.944  31.580 1.00 127.75 ? 280 THR B CA  1 
ATOM   5749  C C   . THR B 1 272 ? -21.771 34.750  30.756 1.00 114.25 ? 280 THR B C   1 
ATOM   5750  O O   . THR B 1 272 ? -21.775 33.634  31.289 1.00 69.82  ? 280 THR B O   1 
ATOM   5751  C CB  . THR B 1 272 ? -21.944 35.955  32.967 1.00 106.34 ? 280 THR B CB  1 
ATOM   5752  O OG1 . THR B 1 272 ? -23.353 35.824  32.788 1.00 110.06 ? 280 THR B OG1 1 
ATOM   5753  C CG2 . THR B 1 272 ? -21.637 37.214  33.746 1.00 69.59  ? 280 THR B CG2 1 
ATOM   5754  N N   . GLY B 1 273 ? -22.169 34.994  29.511 1.00 108.40 ? 281 GLY B N   1 
ATOM   5755  C CA  . GLY B 1 273 ? -22.647 33.909  28.638 1.00 106.56 ? 281 GLY B CA  1 
ATOM   5756  C C   . GLY B 1 273 ? -23.916 33.287  29.184 1.00 134.50 ? 281 GLY B C   1 
ATOM   5757  O O   . GLY B 1 273 ? -24.461 32.387  28.521 1.00 147.18 ? 281 GLY B O   1 
ATOM   5758  N N   . LYS B 1 274 ? -24.379 33.756  30.343 1.00 135.82 ? 282 LYS B N   1 
ATOM   5759  C CA  . LYS B 1 274 ? -25.579 33.160  30.986 1.00 125.16 ? 282 LYS B CA  1 
ATOM   5760  C C   . LYS B 1 274 ? -26.832 33.822  30.415 1.00 132.13 ? 282 LYS B C   1 
ATOM   5761  O O   . LYS B 1 274 ? -26.729 34.467  29.361 1.00 139.02 ? 282 LYS B O   1 
ATOM   5762  C CB  . LYS B 1 274 ? -25.501 33.325  32.506 1.00 113.87 ? 282 LYS B CB  1 
ATOM   5763  C CG  . LYS B 1 274 ? -26.593 32.638  33.317 1.00 102.29 ? 282 LYS B CG  1 
ATOM   5764  C CD  . LYS B 1 274 ? -26.769 31.177  32.976 1.00 100.01 ? 282 LYS B CD  1 
ATOM   5765  C CE  . LYS B 1 274 ? -27.945 30.549  33.692 1.00 96.43  ? 282 LYS B CE  1 
ATOM   5766  N NZ  . LYS B 1 274 ? -27.815 30.670  35.163 1.00 108.80 ? 282 LYS B NZ  1 
ATOM   5767  N N   . GLU B 1 275 ? -27.965 33.670  31.096 1.00 135.02 ? 283 GLU B N   1 
ATOM   5768  C CA  . GLU B 1 275 ? -29.242 34.211  30.575 1.00 138.13 ? 283 GLU B CA  1 
ATOM   5769  C C   . GLU B 1 275 ? -29.734 35.332  31.489 1.00 118.79 ? 283 GLU B C   1 
ATOM   5770  O O   . GLU B 1 275 ? -29.543 35.222  32.712 1.00 122.23 ? 283 GLU B O   1 
ATOM   5771  C CB  . GLU B 1 275 ? -30.270 33.082  30.487 1.00 139.46 ? 283 GLU B CB  1 
ATOM   5772  C CG  . GLU B 1 275 ? -30.599 32.453  31.824 1.00 124.45 ? 283 GLU B CG  1 
ATOM   5773  C CD  . GLU B 1 275 ? -31.607 31.326  31.715 1.00 112.06 ? 283 GLU B CD  1 
ATOM   5774  O OE1 . GLU B 1 275 ? -31.944 30.952  30.576 1.00 71.08  ? 283 GLU B OE1 1 
ATOM   5775  O OE2 . GLU B 1 275 ? -32.051 30.828  32.766 1.00 98.52  ? 283 GLU B OE2 1 
ATOM   5776  N N   . ILE B 1 276 ? -30.337 36.370  30.910 1.00 130.80 ? 284 ILE B N   1 
ATOM   5777  C CA  . ILE B 1 276 ? -30.925 37.461  31.737 1.00 118.68 ? 284 ILE B CA  1 
ATOM   5778  C C   . ILE B 1 276 ? -32.443 37.344  31.626 1.00 118.60 ? 284 ILE B C   1 
ATOM   5779  O O   . ILE B 1 276 ? -32.949 37.334  30.493 1.00 87.22  ? 284 ILE B O   1 
ATOM   5780  C CB  . ILE B 1 276 ? -30.422 38.839  31.273 1.00 91.97  ? 284 ILE B CB  1 
ATOM   5781  C CG1 . ILE B 1 276 ? -28.941 38.807  30.890 1.00 97.90  ? 284 ILE B CG1 1 
ATOM   5782  C CG2 . ILE B 1 276 ? -30.711 39.898  32.324 1.00 74.99  ? 284 ILE B CG2 1 
ATOM   5783  C CD1 . ILE B 1 276 ? -28.424 40.121  30.360 1.00 86.05  ? 284 ILE B CD1 1 
ATOM   5784  N N   . LEU B 1 277 ? -33.134 37.236  32.761 1.00 112.88 ? 285 LEU B N   1 
ATOM   5785  C CA  . LEU B 1 277 ? -34.579 37.076  32.725 1.00 100.44 ? 285 LEU B CA  1 
ATOM   5786  C C   . LEU B 1 277 ? -35.309 38.415  32.730 1.00 104.14 ? 285 LEU B C   1 
ATOM   5787  O O   . LEU B 1 277 ? -35.091 39.258  33.599 1.00 111.53 ? 285 LEU B O   1 
ATOM   5788  C CB  . LEU B 1 277 ? -35.172 36.123  33.758 1.00 70.80  ? 285 LEU B CB  1 
ATOM   5789  C CG  . LEU B 1 277 ? -34.791 34.645  33.581 1.00 62.46  ? 285 LEU B CG  1 
ATOM   5790  C CD1 . LEU B 1 277 ? -35.257 33.704  34.681 1.00 48.33  ? 285 LEU B CD1 1 
ATOM   5791  C CD2 . LEU B 1 277 ? -35.159 34.016  32.250 1.00 65.90  ? 285 LEU B CD2 1 
ATOM   5792  N N   . TYR B 1 278 ? -36.232 38.551  31.759 1.00 104.72 ? 286 TYR B N   1 
ATOM   5793  C CA  . TYR B 1 278 ? -37.304 39.535  31.773 1.00 114.62 ? 286 TYR B CA  1 
ATOM   5794  C C   . TYR B 1 278 ? -37.724 39.858  33.205 1.00 112.54 ? 286 TYR B C   1 
ATOM   5795  O O   . TYR B 1 278 ? -38.071 38.968  33.971 1.00 88.68  ? 286 TYR B O   1 
ATOM   5796  C CB  . TYR B 1 278 ? -38.535 39.062  30.999 1.00 95.04  ? 286 TYR B CB  1 
ATOM   5797  C CG  . TYR B 1 278 ? -38.429 39.344  29.509 1.00 112.06 ? 286 TYR B CG  1 
ATOM   5798  C CD1 . TYR B 1 278 ? -38.156 40.631  29.025 1.00 108.72 ? 286 TYR B CD1 1 
ATOM   5799  C CD2 . TYR B 1 278 ? -38.638 38.319  28.582 1.00 125.67 ? 286 TYR B CD2 1 
ATOM   5800  C CE1 . TYR B 1 278 ? -38.020 40.866  27.661 1.00 108.98 ? 286 TYR B CE1 1 
ATOM   5801  C CE2 . TYR B 1 278 ? -38.566 38.544  27.214 1.00 114.34 ? 286 TYR B CE2 1 
ATOM   5802  C CZ  . TYR B 1 278 ? -38.257 39.823  26.763 1.00 126.30 ? 286 TYR B CZ  1 
ATOM   5803  O OH  . TYR B 1 278 ? -38.203 39.997  25.408 1.00 117.05 ? 286 TYR B OH  1 
ATOM   5804  N N   . ASN B 1 279 ? -37.696 41.151  33.526 1.00 108.92 ? 287 ASN B N   1 
ATOM   5805  C CA  . ASN B 1 279 ? -37.890 41.628  34.877 1.00 90.04  ? 287 ASN B CA  1 
ATOM   5806  C C   . ASN B 1 279 ? -39.291 42.239  35.059 1.00 113.68 ? 287 ASN B C   1 
ATOM   5807  O O   . ASN B 1 279 ? -39.622 42.760  36.122 1.00 116.72 ? 287 ASN B O   1 
ATOM   5808  C CB  . ASN B 1 279 ? -36.823 42.677  35.146 1.00 70.74  ? 287 ASN B CB  1 
ATOM   5809  C CG  . ASN B 1 279 ? -36.703 42.913  36.629 1.00 70.49  ? 287 ASN B CG  1 
ATOM   5810  O OD1 . ASN B 1 279 ? -37.442 42.307  37.409 1.00 118.02 ? 287 ASN B OD1 1 
ATOM   5811  N ND2 . ASN B 1 279 ? -35.763 43.725  37.061 1.00 61.86  ? 287 ASN B ND2 1 
ATOM   5812  N N   . LEU B 1 280 ? -40.110 42.192  34.004 1.00 114.76 ? 288 LEU B N   1 
ATOM   5813  C CA  . LEU B 1 280 ? -41.253 43.093  33.883 1.00 101.33 ? 288 LEU B CA  1 
ATOM   5814  C C   . LEU B 1 280 ? -42.279 42.736  34.949 1.00 91.41  ? 288 LEU B C   1 
ATOM   5815  O O   . LEU B 1 280 ? -42.951 43.618  35.482 1.00 84.01  ? 288 LEU B O   1 
ATOM   5816  C CB  . LEU B 1 280 ? -41.816 43.053  32.466 1.00 84.64  ? 288 LEU B CB  1 
ATOM   5817  C CG  . LEU B 1 280 ? -40.780 43.340  31.368 1.00 82.46  ? 288 LEU B CG  1 
ATOM   5818  C CD1 . LEU B 1 280 ? -41.281 43.116  29.953 1.00 96.34  ? 288 LEU B CD1 1 
ATOM   5819  C CD2 . LEU B 1 280 ? -40.181 44.723  31.525 1.00 68.03  ? 288 LEU B CD2 1 
ATOM   5820  N N   . GLU B 1 281 ? -42.390 41.433  35.226 1.00 65.94  ? 289 GLU B N   1 
ATOM   5821  C CA  . GLU B 1 281 ? -43.396 40.923  36.143 1.00 64.22  ? 289 GLU B CA  1 
ATOM   5822  C C   . GLU B 1 281 ? -43.304 41.629  37.496 1.00 86.87  ? 289 GLU B C   1 
ATOM   5823  O O   . GLU B 1 281 ? -44.308 42.208  37.967 1.00 119.39 ? 289 GLU B O   1 
ATOM   5824  C CB  . GLU B 1 281 ? -43.348 39.407  36.275 1.00 44.29  ? 289 GLU B CB  1 
ATOM   5825  C CG  . GLU B 1 281 ? -44.401 38.880  37.228 1.00 56.62  ? 289 GLU B CG  1 
ATOM   5826  C CD  . GLU B 1 281 ? -44.615 37.388  37.148 1.00 86.27  ? 289 GLU B CD  1 
ATOM   5827  O OE1 . GLU B 1 281 ? -43.574 36.673  37.150 1.00 74.72  ? 289 GLU B OE1 1 
ATOM   5828  O OE2 . GLU B 1 281 ? -45.810 36.968  37.071 1.00 111.85 ? 289 GLU B OE2 1 
ATOM   5829  N N   . SER B 1 282 ? -42.135 41.592  38.157 1.00 61.63  ? 290 SER B N   1 
ATOM   5830  C CA  . SER B 1 282 ? -42.245 42.148  39.494 1.00 69.56  ? 290 SER B CA  1 
ATOM   5831  C C   . SER B 1 282 ? -42.438 43.677  39.461 1.00 73.41  ? 290 SER B C   1 
ATOM   5832  O O   . SER B 1 282 ? -43.313 44.214  40.152 1.00 64.91  ? 290 SER B O   1 
ATOM   5833  C CB  . SER B 1 282 ? -41.270 41.537  40.509 1.00 70.08  ? 290 SER B CB  1 
ATOM   5834  O OG  . SER B 1 282 ? -40.927 42.455  41.518 1.00 90.05  ? 290 SER B OG  1 
ATOM   5835  N N   . LEU B 1 283 ? -41.764 44.370  38.536 1.00 54.64  ? 291 LEU B N   1 
ATOM   5836  C CA  . LEU B 1 283 ? -41.930 45.821  38.463 1.00 65.15  ? 291 LEU B CA  1 
ATOM   5837  C C   . LEU B 1 283 ? -43.399 46.204  38.264 1.00 80.53  ? 291 LEU B C   1 
ATOM   5838  O O   . LEU B 1 283 ? -43.941 46.977  39.059 1.00 69.93  ? 291 LEU B O   1 
ATOM   5839  C CB  . LEU B 1 283 ? -41.067 46.328  37.307 1.00 67.62  ? 291 LEU B CB  1 
ATOM   5840  C CG  . LEU B 1 283 ? -39.579 46.054  37.514 1.00 59.02  ? 291 LEU B CG  1 
ATOM   5841  C CD1 . LEU B 1 283 ? -38.769 46.039  36.282 1.00 48.01  ? 291 LEU B CD1 1 
ATOM   5842  C CD2 . LEU B 1 283 ? -39.062 47.098  38.501 1.00 58.67  ? 291 LEU B CD2 1 
ATOM   5843  N N   . ILE B 1 284 ? -44.032 45.674  37.202 1.00 71.83  ? 292 ILE B N   1 
ATOM   5844  C CA  . ILE B 1 284 ? -45.402 46.041  36.903 1.00 70.97  ? 292 ILE B CA  1 
ATOM   5845  C C   . ILE B 1 284 ? -46.319 45.638  38.063 1.00 80.06  ? 292 ILE B C   1 
ATOM   5846  O O   . ILE B 1 284 ? -47.121 46.456  38.537 1.00 85.64  ? 292 ILE B O   1 
ATOM   5847  C CB  . ILE B 1 284 ? -45.861 45.430  35.581 1.00 84.84  ? 292 ILE B CB  1 
ATOM   5848  C CG1 . ILE B 1 284 ? -45.064 45.972  34.408 1.00 107.80 ? 292 ILE B CG1 1 
ATOM   5849  C CG2 . ILE B 1 284 ? -47.361 45.689  35.422 1.00 79.13  ? 292 ILE B CG2 1 
ATOM   5850  C CD1 . ILE B 1 284 ? -45.247 45.156  33.131 1.00 113.76 ? 292 ILE B CD1 1 
ATOM   5851  N N   . ASN B 1 285 ? -46.145 44.408  38.566 1.00 67.62  ? 293 ASN B N   1 
ATOM   5852  C CA  . ASN B 1 285 ? -46.928 43.973  39.705 1.00 73.23  ? 293 ASN B CA  1 
ATOM   5853  C C   . ASN B 1 285 ? -46.791 44.962  40.862 1.00 91.66  ? 293 ASN B C   1 
ATOM   5854  O O   . ASN B 1 285 ? -47.804 45.362  41.483 1.00 71.50  ? 293 ASN B O   1 
ATOM   5855  C CB  . ASN B 1 285 ? -46.608 42.551  40.128 1.00 69.28  ? 293 ASN B CB  1 
ATOM   5856  C CG  . ASN B 1 285 ? -47.259 41.573  39.206 1.00 98.73  ? 293 ASN B CG  1 
ATOM   5857  O OD1 . ASN B 1 285 ? -48.418 41.767  38.809 1.00 105.46 ? 293 ASN B OD1 1 
ATOM   5858  N ND2 . ASN B 1 285 ? -46.519 40.540  38.849 1.00 109.34 ? 293 ASN B ND2 1 
ATOM   5859  N N   . SER B 1 286 ? -45.531 45.358  41.143 1.00 76.94  ? 294 SER B N   1 
ATOM   5860  C CA  . SER B 1 286 ? -45.305 46.224  42.293 1.00 76.49  ? 294 SER B CA  1 
ATOM   5861  C C   . SER B 1 286 ? -45.874 47.611  42.018 1.00 64.42  ? 294 SER B C   1 
ATOM   5862  O O   . SER B 1 286 ? -46.331 48.264  42.940 1.00 48.19  ? 294 SER B O   1 
ATOM   5863  C CB  . SER B 1 286 ? -43.892 46.247  42.693 1.00 59.72  ? 294 SER B CB  1 
ATOM   5864  O OG  . SER B 1 286 ? -43.326 45.246  41.854 1.00 46.39  ? 294 SER B OG  1 
ATOM   5865  N N   . ALA B 1 287 ? -45.874 48.004  40.737 1.00 52.07  ? 295 ALA B N   1 
ATOM   5866  C CA  . ALA B 1 287 ? -46.389 49.305  40.347 1.00 56.91  ? 295 ALA B CA  1 
ATOM   5867  C C   . ALA B 1 287 ? -47.879 49.381  40.662 1.00 61.68  ? 295 ALA B C   1 
ATOM   5868  O O   . ALA B 1 287 ? -48.346 50.333  41.304 1.00 60.16  ? 295 ALA B O   1 
ATOM   5869  C CB  . ALA B 1 287 ? -46.125 49.573  38.898 1.00 50.23  ? 295 ALA B CB  1 
ATOM   5870  N N   . VAL B 1 288 ? -48.605 48.349  40.236 1.00 57.71  ? 296 VAL B N   1 
ATOM   5871  C CA  . VAL B 1 288 ? -50.027 48.324  40.517 1.00 63.65  ? 296 VAL B CA  1 
ATOM   5872  C C   . VAL B 1 288 ? -50.312 48.284  42.019 1.00 63.36  ? 296 VAL B C   1 
ATOM   5873  O O   . VAL B 1 288 ? -51.226 48.974  42.526 1.00 43.88  ? 296 VAL B O   1 
ATOM   5874  C CB  . VAL B 1 288 ? -50.695 47.161  39.801 1.00 47.88  ? 296 VAL B CB  1 
ATOM   5875  C CG1 . VAL B 1 288 ? -52.155 47.122  40.216 1.00 43.57  ? 296 VAL B CG1 1 
ATOM   5876  C CG2 . VAL B 1 288 ? -50.549 47.328  38.291 1.00 33.98  ? 296 VAL B CG2 1 
ATOM   5877  N N   . PHE B 1 289 ? -49.504 47.483  42.721 1.00 68.50  ? 297 PHE B N   1 
ATOM   5878  C CA  . PHE B 1 289 ? -49.702 47.346  44.162 1.00 104.35 ? 297 PHE B CA  1 
ATOM   5879  C C   . PHE B 1 289 ? -48.405 46.848  44.797 1.00 90.56  ? 297 PHE B C   1 
ATOM   5880  O O   . PHE B 1 289 ? -47.865 45.834  44.356 1.00 97.43  ? 297 PHE B O   1 
ATOM   5881  C CB  . PHE B 1 289 ? -50.881 46.476  44.633 1.00 102.20 ? 297 PHE B CB  1 
ATOM   5882  C CG  . PHE B 1 289 ? -51.077 46.573  46.132 1.00 101.63 ? 297 PHE B CG  1 
ATOM   5883  C CD1 . PHE B 1 289 ? -51.864 47.566  46.704 1.00 145.82 ? 297 PHE B CD1 1 
ATOM   5884  C CD2 . PHE B 1 289 ? -50.418 45.708  46.983 1.00 122.31 ? 297 PHE B CD2 1 
ATOM   5885  C CE1 . PHE B 1 289 ? -52.004 47.666  48.088 1.00 143.58 ? 297 PHE B CE1 1 
ATOM   5886  C CE2 . PHE B 1 289 ? -50.597 45.770  48.358 1.00 114.96 ? 297 PHE B CE2 1 
ATOM   5887  C CZ  . PHE B 1 289 ? -51.357 46.768  48.919 1.00 115.77 ? 297 PHE B CZ  1 
ATOM   5888  N N   . PRO B 1 290 ? -47.857 47.479  45.862 1.00 77.50  ? 298 PRO B N   1 
ATOM   5889  C CA  . PRO B 1 290 ? -48.428 48.638  46.580 1.00 92.10  ? 298 PRO B CA  1 
ATOM   5890  C C   . PRO B 1 290 ? -48.041 50.027  46.016 1.00 92.78  ? 298 PRO B C   1 
ATOM   5891  O O   . PRO B 1 290 ? -47.716 51.033  46.686 1.00 73.54  ? 298 PRO B O   1 
ATOM   5892  C CB  . PRO B 1 290 ? -47.632 48.407  47.871 1.00 96.45  ? 298 PRO B CB  1 
ATOM   5893  C CG  . PRO B 1 290 ? -46.198 48.196  47.353 1.00 71.62  ? 298 PRO B CG  1 
ATOM   5894  C CD  . PRO B 1 290 ? -46.539 47.091  46.372 1.00 69.99  ? 298 PRO B CD  1 
ATOM   5895  N N   . GLY B 1 291 ? -47.989 50.106  44.703 1.00 70.79  ? 299 GLY B N   1 
ATOM   5896  C CA  . GLY B 1 291 ? -47.456 51.337  44.168 1.00 66.11  ? 299 GLY B CA  1 
ATOM   5897  C C   . GLY B 1 291 ? -48.567 52.343  43.997 1.00 72.57  ? 299 GLY B C   1 
ATOM   5898  O O   . GLY B 1 291 ? -48.494 53.403  44.612 1.00 96.52  ? 299 GLY B O   1 
ATOM   5899  N N   . LEU B 1 292 ? -49.571 51.985  43.183 1.00 60.29  ? 300 LEU B N   1 
ATOM   5900  C CA  . LEU B 1 292 ? -50.558 52.979  42.765 1.00 48.34  ? 300 LEU B CA  1 
ATOM   5901  C C   . LEU B 1 292 ? -51.929 52.668  43.355 1.00 57.44  ? 300 LEU B C   1 
ATOM   5902  O O   . LEU B 1 292 ? -52.657 53.587  43.699 1.00 65.76  ? 300 LEU B O   1 
ATOM   5903  C CB  . LEU B 1 292 ? -50.655 53.111  41.250 1.00 36.09  ? 300 LEU B CB  1 
ATOM   5904  C CG  . LEU B 1 292 ? -49.356 53.536  40.549 1.00 46.20  ? 300 LEU B CG  1 
ATOM   5905  C CD1 . LEU B 1 292 ? -49.261 53.258  39.039 1.00 38.26  ? 300 LEU B CD1 1 
ATOM   5906  C CD2 . LEU B 1 292 ? -48.922 54.952  40.774 1.00 49.98  ? 300 LEU B CD2 1 
ATOM   5907  N N   . GLN B 1 293 ? -52.319 51.389  43.433 1.00 64.09  ? 301 GLN B N   1 
ATOM   5908  C CA  . GLN B 1 293 ? -53.721 51.090  43.712 1.00 57.07  ? 301 GLN B CA  1 
ATOM   5909  C C   . GLN B 1 293 ? -53.895 50.626  45.165 1.00 54.73  ? 301 GLN B C   1 
ATOM   5910  O O   . GLN B 1 293 ? -52.922 50.454  45.872 1.00 49.53  ? 301 GLN B O   1 
ATOM   5911  C CB  . GLN B 1 293 ? -54.269 50.097  42.696 1.00 59.57  ? 301 GLN B CB  1 
ATOM   5912  C CG  . GLN B 1 293 ? -54.206 50.624  41.273 1.00 77.55  ? 301 GLN B CG  1 
ATOM   5913  C CD  . GLN B 1 293 ? -55.042 49.802  40.319 1.00 87.17  ? 301 GLN B CD  1 
ATOM   5914  O OE1 . GLN B 1 293 ? -55.227 50.194  39.159 1.00 64.61  ? 301 GLN B OE1 1 
ATOM   5915  N NE2 . GLN B 1 293 ? -55.596 48.694  40.828 1.00 93.93  ? 301 GLN B NE2 1 
ATOM   5916  N N   . GLY B 1 294 ? -55.141 50.490  45.643 1.00 54.67  ? 302 GLY B N   1 
ATOM   5917  C CA  . GLY B 1 294 ? -55.375 49.701  46.839 1.00 53.43  ? 302 GLY B CA  1 
ATOM   5918  C C   . GLY B 1 294 ? -56.184 48.456  46.478 1.00 62.57  ? 302 GLY B C   1 
ATOM   5919  O O   . GLY B 1 294 ? -55.897 47.744  45.503 1.00 74.18  ? 302 GLY B O   1 
ATOM   5920  N N   . GLY B 1 295 ? -57.278 48.283  47.220 1.00 77.12  ? 303 GLY B N   1 
ATOM   5921  C CA  . GLY B 1 295 ? -58.134 47.111  47.103 1.00 85.07  ? 303 GLY B CA  1 
ATOM   5922  C C   . GLY B 1 295 ? -58.581 46.855  45.680 1.00 73.07  ? 303 GLY B C   1 
ATOM   5923  O O   . GLY B 1 295 ? -59.165 47.734  45.057 1.00 77.83  ? 303 GLY B O   1 
ATOM   5924  N N   . PRO B 1 296 ? -58.316 45.655  45.130 1.00 80.20  ? 304 PRO B N   1 
ATOM   5925  C CA  . PRO B 1 296 ? -58.751 45.339  43.768 1.00 90.00  ? 304 PRO B CA  1 
ATOM   5926  C C   . PRO B 1 296 ? -60.277 45.395  43.714 1.00 116.33 ? 304 PRO B C   1 
ATOM   5927  O O   . PRO B 1 296 ? -60.931 45.160  44.739 1.00 145.35 ? 304 PRO B O   1 
ATOM   5928  C CB  . PRO B 1 296 ? -58.200 43.911  43.614 1.00 87.13  ? 304 PRO B CB  1 
ATOM   5929  C CG  . PRO B 1 296 ? -57.002 43.874  44.528 1.00 111.03 ? 304 PRO B CG  1 
ATOM   5930  C CD  . PRO B 1 296 ? -57.540 44.578  45.764 1.00 106.42 ? 304 PRO B CD  1 
ATOM   5931  N N   . HIS B 1 297 ? -60.842 45.736  42.535 1.00 102.04 ? 305 HIS B N   1 
ATOM   5932  C CA  . HIS B 1 297 ? -62.301 45.747  42.397 1.00 99.28  ? 305 HIS B CA  1 
ATOM   5933  C C   . HIS B 1 297 ? -62.783 44.360  41.986 1.00 102.23 ? 305 HIS B C   1 
ATOM   5934  O O   . HIS B 1 297 ? -62.956 44.131  40.795 1.00 79.83  ? 305 HIS B O   1 
ATOM   5935  C CB  . HIS B 1 297 ? -62.824 46.829  41.436 1.00 55.89  ? 305 HIS B CB  1 
ATOM   5936  C CG  . HIS B 1 297 ? -62.649 48.172  42.023 1.00 71.85  ? 305 HIS B CG  1 
ATOM   5937  N ND1 . HIS B 1 297 ? -63.293 49.300  41.576 1.00 68.73  ? 305 HIS B ND1 1 
ATOM   5938  C CD2 . HIS B 1 297 ? -61.888 48.592  43.057 1.00 86.15  ? 305 HIS B CD2 1 
ATOM   5939  C CE1 . HIS B 1 297 ? -62.875 50.354  42.304 1.00 66.77  ? 305 HIS B CE1 1 
ATOM   5940  N NE2 . HIS B 1 297 ? -62.018 49.956  43.191 1.00 66.95  ? 305 HIS B NE2 1 
ATOM   5941  N N   . ASN B 1 298 ? -63.002 43.448  42.952 1.00 93.23  ? 306 ASN B N   1 
ATOM   5942  C CA  . ASN B 1 298 ? -63.106 42.054  42.546 1.00 113.25 ? 306 ASN B CA  1 
ATOM   5943  C C   . ASN B 1 298 ? -64.327 41.807  41.665 1.00 117.39 ? 306 ASN B C   1 
ATOM   5944  O O   . ASN B 1 298 ? -64.307 40.960  40.766 1.00 101.71 ? 306 ASN B O   1 
ATOM   5945  C CB  . ASN B 1 298 ? -63.042 41.121  43.738 1.00 126.93 ? 306 ASN B CB  1 
ATOM   5946  C CG  . ASN B 1 298 ? -61.680 41.135  44.403 1.00 161.05 ? 306 ASN B CG  1 
ATOM   5947  O OD1 . ASN B 1 298 ? -60.687 40.627  43.846 1.00 109.56 ? 306 ASN B OD1 1 
ATOM   5948  N ND2 . ASN B 1 298 ? -61.626 41.685  45.614 1.00 174.01 ? 306 ASN B ND2 1 
ATOM   5949  N N   . HIS B 1 299 ? -65.396 42.557  41.936 1.00 113.38 ? 307 HIS B N   1 
ATOM   5950  C CA  . HIS B 1 299 ? -66.612 42.460  41.146 1.00 114.24 ? 307 HIS B CA  1 
ATOM   5951  C C   . HIS B 1 299 ? -66.332 42.844  39.696 1.00 121.01 ? 307 HIS B C   1 
ATOM   5952  O O   . HIS B 1 299 ? -66.950 42.302  38.784 1.00 123.22 ? 307 HIS B O   1 
ATOM   5953  C CB  . HIS B 1 299 ? -67.680 43.369  41.752 1.00 129.04 ? 307 HIS B CB  1 
ATOM   5954  C CG  . HIS B 1 299 ? -67.270 44.801  41.871 1.00 97.49  ? 307 HIS B CG  1 
ATOM   5955  N ND1 . HIS B 1 299 ? -66.297 45.285  42.712 1.00 73.30  ? 307 HIS B ND1 1 
ATOM   5956  C CD2 . HIS B 1 299 ? -67.857 45.864  41.364 1.00 82.93  ? 307 HIS B CD2 1 
ATOM   5957  C CE1 . HIS B 1 299 ? -66.222 46.576  42.610 1.00 70.32  ? 307 HIS B CE1 1 
ATOM   5958  N NE2 . HIS B 1 299 ? -67.208 46.960  41.841 1.00 72.24  ? 307 HIS B NE2 1 
ATOM   5959  N N   . ALA B 1 300 ? -65.388 43.777  39.490 1.00 113.81 ? 308 ALA B N   1 
ATOM   5960  C CA  . ALA B 1 300 ? -64.976 44.133  38.142 1.00 108.32 ? 308 ALA B CA  1 
ATOM   5961  C C   . ALA B 1 300 ? -64.127 43.034  37.520 1.00 97.47  ? 308 ALA B C   1 
ATOM   5962  O O   . ALA B 1 300 ? -64.292 42.751  36.331 1.00 74.43  ? 308 ALA B O   1 
ATOM   5963  C CB  . ALA B 1 300 ? -64.277 45.452  38.090 1.00 121.85 ? 308 ALA B CB  1 
ATOM   5964  N N   . ILE B 1 301 ? -63.269 42.403  38.339 1.00 92.43  ? 309 ILE B N   1 
ATOM   5965  C CA  . ILE B 1 301 ? -62.394 41.357  37.831 1.00 95.38  ? 309 ILE B CA  1 
ATOM   5966  C C   . ILE B 1 301 ? -63.251 40.180  37.372 1.00 81.18  ? 309 ILE B C   1 
ATOM   5967  O O   . ILE B 1 301 ? -62.981 39.587  36.307 1.00 56.77  ? 309 ILE B O   1 
ATOM   5968  C CB  . ILE B 1 301 ? -61.322 40.959  38.857 1.00 88.11  ? 309 ILE B CB  1 
ATOM   5969  C CG1 . ILE B 1 301 ? -60.304 42.055  38.981 1.00 80.09  ? 309 ILE B CG1 1 
ATOM   5970  C CG2 . ILE B 1 301 ? -60.615 39.672  38.431 1.00 85.61  ? 309 ILE B CG2 1 
ATOM   5971  C CD1 . ILE B 1 301 ? -59.466 41.901  40.225 1.00 99.47  ? 309 ILE B CD1 1 
ATOM   5972  N N   . ALA B 1 302 ? -64.313 39.914  38.151 1.00 57.31  ? 310 ALA B N   1 
ATOM   5973  C CA  . ALA B 1 302 ? -65.280 38.887  37.773 1.00 79.01  ? 310 ALA B CA  1 
ATOM   5974  C C   . ALA B 1 302 ? -65.867 39.185  36.389 1.00 83.15  ? 310 ALA B C   1 
ATOM   5975  O O   . ALA B 1 302 ? -65.921 38.320  35.509 1.00 80.67  ? 310 ALA B O   1 
ATOM   5976  C CB  . ALA B 1 302 ? -66.366 38.797  38.826 1.00 76.75  ? 310 ALA B CB  1 
ATOM   5977  N N   . GLY B 1 303 ? -66.328 40.431  36.218 1.00 69.44  ? 311 GLY B N   1 
ATOM   5978  C CA  . GLY B 1 303 ? -66.903 40.859  34.958 1.00 82.02  ? 311 GLY B CA  1 
ATOM   5979  C C   . GLY B 1 303 ? -65.926 40.666  33.800 1.00 87.47  ? 311 GLY B C   1 
ATOM   5980  O O   . GLY B 1 303 ? -66.315 40.231  32.717 1.00 74.77  ? 311 GLY B O   1 
ATOM   5981  N N   . VAL B 1 304 ? -64.651 40.968  34.054 1.00 68.24  ? 312 VAL B N   1 
ATOM   5982  C CA  . VAL B 1 304 ? -63.632 40.834  33.028 1.00 67.28  ? 312 VAL B CA  1 
ATOM   5983  C C   . VAL B 1 304 ? -63.463 39.364  32.672 1.00 73.39  ? 312 VAL B C   1 
ATOM   5984  O O   . VAL B 1 304 ? -63.338 39.015  31.488 1.00 73.27  ? 312 VAL B O   1 
ATOM   5985  C CB  . VAL B 1 304 ? -62.297 41.430  33.508 1.00 68.29  ? 312 VAL B CB  1 
ATOM   5986  C CG1 . VAL B 1 304 ? -61.123 41.168  32.519 1.00 51.77  ? 312 VAL B CG1 1 
ATOM   5987  C CG2 . VAL B 1 304 ? -62.515 42.907  33.868 1.00 66.71  ? 312 VAL B CG2 1 
ATOM   5988  N N   . ALA B 1 305 ? -63.438 38.536  33.723 1.00 66.14  ? 313 ALA B N   1 
ATOM   5989  C CA  . ALA B 1 305 ? -63.316 37.109  33.526 1.00 90.25  ? 313 ALA B CA  1 
ATOM   5990  C C   . ALA B 1 305 ? -64.426 36.651  32.571 1.00 94.88  ? 313 ALA B C   1 
ATOM   5991  O O   . ALA B 1 305 ? -64.140 36.064  31.527 1.00 104.74 ? 313 ALA B O   1 
ATOM   5992  C CB  . ALA B 1 305 ? -63.325 36.401  34.871 1.00 83.39  ? 313 ALA B CB  1 
ATOM   5993  N N   . VAL B 1 306 ? -65.680 36.988  32.903 1.00 72.35  ? 314 VAL B N   1 
ATOM   5994  C CA  . VAL B 1 306 ? -66.847 36.577  32.141 1.00 89.12  ? 314 VAL B CA  1 
ATOM   5995  C C   . VAL B 1 306 ? -66.678 36.986  30.681 1.00 89.71  ? 314 VAL B C   1 
ATOM   5996  O O   . VAL B 1 306 ? -66.939 36.175  29.764 1.00 86.51  ? 314 VAL B O   1 
ATOM   5997  C CB  . VAL B 1 306 ? -68.172 37.128  32.701 1.00 95.29  ? 314 VAL B CB  1 
ATOM   5998  C CG1 . VAL B 1 306 ? -69.286 36.960  31.687 1.00 64.16  ? 314 VAL B CG1 1 
ATOM   5999  C CG2 . VAL B 1 306 ? -68.547 36.477  34.028 1.00 97.05  ? 314 VAL B CG2 1 
ATOM   6000  N N   . ALA B 1 307 ? -66.217 38.239  30.497 1.00 77.30  ? 315 ALA B N   1 
ATOM   6001  C CA  . ALA B 1 307 ? -65.980 38.797  29.170 1.00 80.11  ? 315 ALA B CA  1 
ATOM   6002  C C   . ALA B 1 307 ? -64.980 37.962  28.380 1.00 91.08  ? 315 ALA B C   1 
ATOM   6003  O O   . ALA B 1 307 ? -65.202 37.710  27.179 1.00 124.44 ? 315 ALA B O   1 
ATOM   6004  C CB  . ALA B 1 307 ? -65.509 40.220  29.275 1.00 64.33  ? 315 ALA B CB  1 
ATOM   6005  N N   . LEU B 1 308 ? -63.883 37.594  29.068 1.00 86.32  ? 316 LEU B N   1 
ATOM   6006  C CA  . LEU B 1 308 ? -62.784 36.875  28.450 1.00 85.95  ? 316 LEU B CA  1 
ATOM   6007  C C   . LEU B 1 308 ? -63.269 35.511  27.968 1.00 95.99  ? 316 LEU B C   1 
ATOM   6008  O O   . LEU B 1 308 ? -62.893 35.057  26.874 1.00 65.35  ? 316 LEU B O   1 
ATOM   6009  C CB  . LEU B 1 308 ? -61.643 36.773  29.454 1.00 60.69  ? 316 LEU B CB  1 
ATOM   6010  C CG  . LEU B 1 308 ? -60.803 38.035  29.636 1.00 63.28  ? 316 LEU B CG  1 
ATOM   6011  C CD1 . LEU B 1 308 ? -59.859 37.825  30.792 1.00 70.17  ? 316 LEU B CD1 1 
ATOM   6012  C CD2 . LEU B 1 308 ? -60.002 38.284  28.371 1.00 65.56  ? 316 LEU B CD2 1 
ATOM   6013  N N   . LYS B 1 309 ? -64.115 34.883  28.797 1.00 104.73 ? 317 LYS B N   1 
ATOM   6014  C CA  . LYS B 1 309 ? -64.654 33.592  28.438 1.00 101.82 ? 317 LYS B CA  1 
ATOM   6015  C C   . LYS B 1 309 ? -65.455 33.743  27.153 1.00 87.24  ? 317 LYS B C   1 
ATOM   6016  O O   . LYS B 1 309 ? -65.358 32.887  26.266 1.00 81.05  ? 317 LYS B O   1 
ATOM   6017  C CB  . LYS B 1 309 ? -65.542 32.930  29.496 1.00 92.39  ? 317 LYS B CB  1 
ATOM   6018  C CG  . LYS B 1 309 ? -66.361 31.766  28.882 1.00 81.58  ? 317 LYS B CG  1 
ATOM   6019  C CD  . LYS B 1 309 ? -67.733 31.610  29.541 1.00 93.47  ? 317 LYS B CD  1 
ATOM   6020  C CE  . LYS B 1 309 ? -68.243 30.205  29.687 1.00 83.57  ? 317 LYS B CE  1 
ATOM   6021  N NZ  . LYS B 1 309 ? -68.565 29.950  31.105 1.00 81.91  ? 317 LYS B NZ  1 
ATOM   6022  N N   . GLN B 1 310 ? -66.277 34.802  27.076 1.00 87.61  ? 318 GLN B N   1 
ATOM   6023  C CA  . GLN B 1 310 ? -67.078 34.970  25.873 1.00 89.19  ? 318 GLN B CA  1 
ATOM   6024  C C   . GLN B 1 310 ? -66.194 35.296  24.685 1.00 83.85  ? 318 GLN B C   1 
ATOM   6025  O O   . GLN B 1 310 ? -66.522 34.918  23.574 1.00 65.38  ? 318 GLN B O   1 
ATOM   6026  C CB  . GLN B 1 310 ? -68.057 36.123  25.960 1.00 82.44  ? 318 GLN B CB  1 
ATOM   6027  C CG  . GLN B 1 310 ? -69.072 35.885  27.065 1.00 75.94  ? 318 GLN B CG  1 
ATOM   6028  C CD  . GLN B 1 310 ? -69.956 37.089  27.186 1.00 89.62  ? 318 GLN B CD  1 
ATOM   6029  O OE1 . GLN B 1 310 ? -70.939 37.015  27.928 1.00 109.50 ? 318 GLN B OE1 1 
ATOM   6030  N NE2 . GLN B 1 310 ? -69.618 38.163  26.451 1.00 102.27 ? 318 GLN B NE2 1 
ATOM   6031  N N   . ALA B 1 311 ? -65.084 35.990  24.949 1.00 101.42 ? 319 ALA B N   1 
ATOM   6032  C CA  . ALA B 1 311 ? -64.156 36.404  23.918 1.00 87.25  ? 319 ALA B CA  1 
ATOM   6033  C C   . ALA B 1 311 ? -63.557 35.212  23.191 1.00 85.88  ? 319 ALA B C   1 
ATOM   6034  O O   . ALA B 1 311 ? -63.093 35.366  22.073 1.00 103.13 ? 319 ALA B O   1 
ATOM   6035  C CB  . ALA B 1 311 ? -63.079 37.271  24.505 1.00 74.01  ? 319 ALA B CB  1 
ATOM   6036  N N   . MET B 1 312 ? -63.527 34.045  23.843 1.00 91.12  ? 320 MET B N   1 
ATOM   6037  C CA  . MET B 1 312 ? -62.894 32.884  23.243 1.00 79.20  ? 320 MET B CA  1 
ATOM   6038  C C   . MET B 1 312 ? -63.923 31.989  22.532 1.00 87.78  ? 320 MET B C   1 
ATOM   6039  O O   . MET B 1 312 ? -63.546 30.952  22.002 1.00 127.91 ? 320 MET B O   1 
ATOM   6040  C CB  . MET B 1 312 ? -62.108 32.098  24.292 1.00 52.93  ? 320 MET B CB  1 
ATOM   6041  C CG  . MET B 1 312 ? -60.799 32.722  24.650 1.00 60.61  ? 320 MET B CG  1 
ATOM   6042  S SD  . MET B 1 312 ? -60.108 32.007  26.178 1.00 80.74  ? 320 MET B SD  1 
ATOM   6043  C CE  . MET B 1 312 ? -61.567 31.812  27.216 1.00 38.43  ? 320 MET B CE  1 
ATOM   6044  N N   . THR B 1 313 ? -65.195 32.397  22.457 1.00 66.43  ? 321 THR B N   1 
ATOM   6045  C CA  . THR B 1 313 ? -66.215 31.705  21.684 1.00 71.05  ? 321 THR B CA  1 
ATOM   6046  C C   . THR B 1 313 ? -66.114 32.038  20.192 1.00 78.37  ? 321 THR B C   1 
ATOM   6047  O O   . THR B 1 313 ? -65.567 33.066  19.777 1.00 60.80  ? 321 THR B O   1 
ATOM   6048  C CB  . THR B 1 313 ? -67.602 32.071  22.216 1.00 94.25  ? 321 THR B CB  1 
ATOM   6049  O OG1 . THR B 1 313 ? -67.975 33.363  21.724 1.00 66.06  ? 321 THR B OG1 1 
ATOM   6050  C CG2 . THR B 1 313 ? -67.670 31.963  23.735 1.00 117.03 ? 321 THR B CG2 1 
ATOM   6051  N N   . LEU B 1 314 ? -66.668 31.138  19.371 1.00 88.59  ? 322 LEU B N   1 
ATOM   6052  C CA  . LEU B 1 314 ? -66.582 31.315  17.931 1.00 86.56  ? 322 LEU B CA  1 
ATOM   6053  C C   . LEU B 1 314 ? -67.483 32.483  17.563 1.00 102.16 ? 322 LEU B C   1 
ATOM   6054  O O   . LEU B 1 314 ? -67.145 33.218  16.635 1.00 82.49  ? 322 LEU B O   1 
ATOM   6055  C CB  . LEU B 1 314 ? -66.867 30.057  17.094 1.00 74.17  ? 322 LEU B CB  1 
ATOM   6056  C CG  . LEU B 1 314 ? -68.007 30.120  16.047 1.00 71.09  ? 322 LEU B CG  1 
ATOM   6057  C CD1 . LEU B 1 314 ? -67.758 30.577  14.532 1.00 41.30  ? 322 LEU B CD1 1 
ATOM   6058  C CD2 . LEU B 1 314 ? -68.916 28.876  16.275 1.00 52.71  ? 322 LEU B CD2 1 
ATOM   6059  N N   . GLU B 1 315 ? -68.611 32.617  18.289 1.00 96.72  ? 323 GLU B N   1 
ATOM   6060  C CA  . GLU B 1 315 ? -69.572 33.688  18.043 1.00 98.32  ? 323 GLU B CA  1 
ATOM   6061  C C   . GLU B 1 315 ? -68.879 35.043  18.150 1.00 111.94 ? 323 GLU B C   1 
ATOM   6062  O O   . GLU B 1 315 ? -69.159 35.921  17.339 1.00 86.83  ? 323 GLU B O   1 
ATOM   6063  C CB  . GLU B 1 315 ? -70.735 33.753  19.032 1.00 88.23  ? 323 GLU B CB  1 
ATOM   6064  C CG  . GLU B 1 315 ? -71.650 32.534  19.033 1.00 78.34  ? 323 GLU B CG  1 
ATOM   6065  C CD  . GLU B 1 315 ? -70.892 31.285  19.452 1.00 89.70  ? 323 GLU B CD  1 
ATOM   6066  O OE1 . GLU B 1 315 ? -69.634 31.240  19.559 1.00 85.34  ? 323 GLU B OE1 1 
ATOM   6067  O OE2 . GLU B 1 315 ? -71.613 30.312  19.680 1.00 98.60  ? 323 GLU B OE2 1 
ATOM   6068  N N   . PHE B 1 316 ? -68.026 35.191  19.179 1.00 113.80 ? 324 PHE B N   1 
ATOM   6069  C CA  . PHE B 1 316 ? -67.190 36.370  19.368 1.00 103.91 ? 324 PHE B CA  1 
ATOM   6070  C C   . PHE B 1 316 ? -66.302 36.594  18.140 1.00 111.40 ? 324 PHE B C   1 
ATOM   6071  O O   . PHE B 1 316 ? -66.324 37.698  17.601 1.00 102.40 ? 324 PHE B O   1 
ATOM   6072  C CB  . PHE B 1 316 ? -66.365 36.329  20.660 1.00 83.74  ? 324 PHE B CB  1 
ATOM   6073  C CG  . PHE B 1 316 ? -65.713 37.638  21.090 1.00 80.73  ? 324 PHE B CG  1 
ATOM   6074  C CD1 . PHE B 1 316 ? -66.422 38.532  21.891 1.00 138.70 ? 324 PHE B CD1 1 
ATOM   6075  C CD2 . PHE B 1 316 ? -64.394 37.964  20.772 1.00 89.97  ? 324 PHE B CD2 1 
ATOM   6076  C CE1 . PHE B 1 316 ? -65.850 39.724  22.315 1.00 168.91 ? 324 PHE B CE1 1 
ATOM   6077  C CE2 . PHE B 1 316 ? -63.809 39.161  21.198 1.00 99.04  ? 324 PHE B CE2 1 
ATOM   6078  C CZ  . PHE B 1 316 ? -64.540 40.021  22.003 1.00 135.92 ? 324 PHE B CZ  1 
ATOM   6079  N N   . LYS B 1 317 ? -65.523 35.569  17.711 1.00 88.99  ? 325 LYS B N   1 
ATOM   6080  C CA  . LYS B 1 317 ? -64.640 35.657  16.552 1.00 108.77 ? 325 LYS B CA  1 
ATOM   6081  C C   . LYS B 1 317 ? -65.444 36.150  15.335 1.00 113.97 ? 325 LYS B C   1 
ATOM   6082  O O   . LYS B 1 317 ? -65.025 37.018  14.565 1.00 109.44 ? 325 LYS B O   1 
ATOM   6083  C CB  . LYS B 1 317 ? -63.863 34.348  16.362 1.00 109.09 ? 325 LYS B CB  1 
ATOM   6084  C CG  . LYS B 1 317 ? -62.728 34.406  15.298 1.00 92.82  ? 325 LYS B CG  1 
ATOM   6085  C CD  . LYS B 1 317 ? -61.848 33.158  15.169 1.00 110.57 ? 325 LYS B CD  1 
ATOM   6086  C CE  . LYS B 1 317 ? -60.948 33.107  13.923 1.00 124.24 ? 325 LYS B CE  1 
ATOM   6087  N NZ  . LYS B 1 317 ? -60.070 31.967  13.540 1.00 80.45  ? 325 LYS B NZ  1 
ATOM   6088  N N   . VAL B 1 318 ? -66.660 35.625  15.214 1.00 81.63  ? 326 VAL B N   1 
ATOM   6089  C CA  . VAL B 1 318 ? -67.535 36.017  14.127 1.00 82.68  ? 326 VAL B CA  1 
ATOM   6090  C C   . VAL B 1 318 ? -67.916 37.499  14.242 1.00 104.67 ? 326 VAL B C   1 
ATOM   6091  O O   . VAL B 1 318 ? -67.759 38.278  13.290 1.00 71.43  ? 326 VAL B O   1 
ATOM   6092  C CB  . VAL B 1 318 ? -68.773 35.108  14.224 1.00 89.06  ? 326 VAL B CB  1 
ATOM   6093  C CG1 . VAL B 1 318 ? -70.007 35.749  13.598 1.00 120.97 ? 326 VAL B CG1 1 
ATOM   6094  C CG2 . VAL B 1 318 ? -68.504 33.732  13.642 1.00 86.33  ? 326 VAL B CG2 1 
ATOM   6095  N N   . TYR B 1 319 ? -68.394 37.873  15.439 1.00 109.82 ? 327 TYR B N   1 
ATOM   6096  C CA  . TYR B 1 319 ? -68.732 39.242  15.803 1.00 100.55 ? 327 TYR B CA  1 
ATOM   6097  C C   . TYR B 1 319 ? -67.614 40.196  15.371 1.00 104.69 ? 327 TYR B C   1 
ATOM   6098  O O   . TYR B 1 319 ? -67.865 41.178  14.694 1.00 86.28  ? 327 TYR B O   1 
ATOM   6099  C CB  . TYR B 1 319 ? -69.026 39.369  17.306 1.00 88.73  ? 327 TYR B CB  1 
ATOM   6100  C CG  . TYR B 1 319 ? -68.966 40.810  17.815 1.00 98.62  ? 327 TYR B CG  1 
ATOM   6101  C CD1 . TYR B 1 319 ? -69.942 41.734  17.462 1.00 82.36  ? 327 TYR B CD1 1 
ATOM   6102  C CD2 . TYR B 1 319 ? -67.937 41.259  18.641 1.00 100.11 ? 327 TYR B CD2 1 
ATOM   6103  C CE1 . TYR B 1 319 ? -69.895 43.046  17.895 1.00 95.57  ? 327 TYR B CE1 1 
ATOM   6104  C CE2 . TYR B 1 319 ? -67.895 42.565  19.099 1.00 102.86 ? 327 TYR B CE2 1 
ATOM   6105  C CZ  . TYR B 1 319 ? -68.858 43.474  18.710 1.00 111.37 ? 327 TYR B CZ  1 
ATOM   6106  O OH  . TYR B 1 319 ? -68.766 44.764  19.165 1.00 104.30 ? 327 TYR B OH  1 
ATOM   6107  N N   . GLN B 1 320 ? -66.367 39.906  15.748 1.00 109.16 ? 328 GLN B N   1 
ATOM   6108  C CA  . GLN B 1 320 ? -65.239 40.746  15.376 1.00 90.09  ? 328 GLN B CA  1 
ATOM   6109  C C   . GLN B 1 320 ? -65.095 40.830  13.855 1.00 94.23  ? 328 GLN B C   1 
ATOM   6110  O O   . GLN B 1 320 ? -64.854 41.906  13.305 1.00 65.39  ? 328 GLN B O   1 
ATOM   6111  C CB  . GLN B 1 320 ? -63.943 40.328  16.082 1.00 74.11  ? 328 GLN B CB  1 
ATOM   6112  C CG  . GLN B 1 320 ? -64.003 40.473  17.601 1.00 84.69  ? 328 GLN B CG  1 
ATOM   6113  C CD  . GLN B 1 320 ? -64.303 41.872  18.118 1.00 76.46  ? 328 GLN B CD  1 
ATOM   6114  O OE1 . GLN B 1 320 ? -64.227 42.878  17.402 1.00 119.76 ? 328 GLN B OE1 1 
ATOM   6115  N NE2 . GLN B 1 320 ? -64.624 41.963  19.396 1.00 70.49  ? 328 GLN B NE2 1 
ATOM   6116  N N   . HIS B 1 321 ? -65.230 39.686  13.165 1.00 98.00  ? 329 HIS B N   1 
ATOM   6117  C CA  . HIS B 1 321 ? -65.086 39.736  11.721 1.00 93.69  ? 329 HIS B CA  1 
ATOM   6118  C C   . HIS B 1 321 ? -66.188 40.654  11.195 1.00 100.44 ? 329 HIS B C   1 
ATOM   6119  O O   . HIS B 1 321 ? -65.916 41.544  10.394 1.00 104.29 ? 329 HIS B O   1 
ATOM   6120  C CB  . HIS B 1 321 ? -64.983 38.364  11.044 1.00 71.00  ? 329 HIS B CB  1 
ATOM   6121  C CG  . HIS B 1 321 ? -63.671 37.663  11.203 1.00 92.31  ? 329 HIS B CG  1 
ATOM   6122  N ND1 . HIS B 1 321 ? -62.623 37.818  10.323 1.00 137.78 ? 329 HIS B ND1 1 
ATOM   6123  C CD2 . HIS B 1 321 ? -63.241 36.752  12.119 1.00 107.98 ? 329 HIS B CD2 1 
ATOM   6124  C CE1 . HIS B 1 321 ? -61.595 37.049  10.705 1.00 146.89 ? 329 HIS B CE1 1 
ATOM   6125  N NE2 . HIS B 1 321 ? -61.947 36.393  11.804 1.00 122.70 ? 329 HIS B NE2 1 
ATOM   6126  N N   . GLN B 1 322 ? -67.413 40.481  11.708 1.00 78.72  ? 330 GLN B N   1 
ATOM   6127  C CA  . GLN B 1 322 ? -68.526 41.327  11.319 1.00 95.52  ? 330 GLN B CA  1 
ATOM   6128  C C   . GLN B 1 322 ? -68.229 42.795  11.629 1.00 106.35 ? 330 GLN B C   1 
ATOM   6129  O O   . GLN B 1 322 ? -68.487 43.665  10.804 1.00 122.99 ? 330 GLN B O   1 
ATOM   6130  C CB  . GLN B 1 322 ? -69.787 40.895  12.056 1.00 110.58 ? 330 GLN B CB  1 
ATOM   6131  C CG  . GLN B 1 322 ? -71.037 41.557  11.506 1.00 134.67 ? 330 GLN B CG  1 
ATOM   6132  C CD  . GLN B 1 322 ? -71.272 41.227  10.048 1.00 152.76 ? 330 GLN B CD  1 
ATOM   6133  O OE1 . GLN B 1 322 ? -71.192 40.060  9.642  1.00 166.94 ? 330 GLN B OE1 1 
ATOM   6134  N NE2 . GLN B 1 322 ? -71.593 42.242  9.255  1.00 125.07 ? 330 GLN B NE2 1 
ATOM   6135  N N   . VAL B 1 323 ? -67.662 43.070  12.805 1.00 111.06 ? 331 VAL B N   1 
ATOM   6136  C CA  . VAL B 1 323 ? -67.357 44.440  13.197 1.00 97.90  ? 331 VAL B CA  1 
ATOM   6137  C C   . VAL B 1 323 ? -66.515 45.089  12.103 1.00 91.96  ? 331 VAL B C   1 
ATOM   6138  O O   . VAL B 1 323 ? -66.788 46.214  11.684 1.00 90.68  ? 331 VAL B O   1 
ATOM   6139  C CB  . VAL B 1 323 ? -66.607 44.497  14.540 1.00 101.79 ? 331 VAL B CB  1 
ATOM   6140  C CG1 . VAL B 1 323 ? -65.748 45.739  14.580 1.00 102.39 ? 331 VAL B CG1 1 
ATOM   6141  C CG2 . VAL B 1 323 ? -67.523 44.415  15.762 1.00 116.22 ? 331 VAL B CG2 1 
ATOM   6142  N N   . VAL B 1 324 ? -65.509 44.348  11.623 1.00 71.73  ? 332 VAL B N   1 
ATOM   6143  C CA  . VAL B 1 324 ? -64.641 44.898  10.599 1.00 68.53  ? 332 VAL B CA  1 
ATOM   6144  C C   . VAL B 1 324 ? -65.361 45.003  9.251  1.00 78.86  ? 332 VAL B C   1 
ATOM   6145  O O   . VAL B 1 324 ? -65.101 45.932  8.470  1.00 64.64  ? 332 VAL B O   1 
ATOM   6146  C CB  . VAL B 1 324 ? -63.289 44.178  10.434 1.00 58.05  ? 332 VAL B CB  1 
ATOM   6147  C CG1 . VAL B 1 324 ? -62.514 44.756  9.264  1.00 44.24  ? 332 VAL B CG1 1 
ATOM   6148  C CG2 . VAL B 1 324 ? -62.452 44.197  11.697 1.00 61.11  ? 332 VAL B CG2 1 
ATOM   6149  N N   . ALA B 1 325 ? -66.211 44.010  8.958  1.00 80.90  ? 333 ALA B N   1 
ATOM   6150  C CA  . ALA B 1 325 ? -66.988 44.014  7.732  1.00 97.86  ? 333 ALA B CA  1 
ATOM   6151  C C   . ALA B 1 325 ? -67.844 45.271  7.686  1.00 94.08  ? 333 ALA B C   1 
ATOM   6152  O O   . ALA B 1 325 ? -67.860 45.980  6.679  1.00 103.89 ? 333 ALA B O   1 
ATOM   6153  C CB  . ALA B 1 325 ? -67.861 42.789  7.687  1.00 104.91 ? 333 ALA B CB  1 
ATOM   6154  N N   . ASN B 1 326 ? -68.524 45.529  8.803  1.00 63.16  ? 334 ASN B N   1 
ATOM   6155  C CA  . ASN B 1 326 ? -69.435 46.647  8.939  1.00 69.49  ? 334 ASN B CA  1 
ATOM   6156  C C   . ASN B 1 326 ? -68.673 47.944  8.686  1.00 84.19  ? 334 ASN B C   1 
ATOM   6157  O O   . ASN B 1 326 ? -69.124 48.807  7.939  1.00 91.61  ? 334 ASN B O   1 
ATOM   6158  C CB  . ASN B 1 326 ? -70.154 46.601  10.289 1.00 67.32  ? 334 ASN B CB  1 
ATOM   6159  C CG  . ASN B 1 326 ? -71.203 45.496  10.359 1.00 83.45  ? 334 ASN B CG  1 
ATOM   6160  O OD1 . ASN B 1 326 ? -71.703 44.981  9.318  1.00 58.08  ? 334 ASN B OD1 1 
ATOM   6161  N ND2 . ASN B 1 326 ? -71.534 45.103  11.591 1.00 71.47  ? 334 ASN B ND2 1 
ATOM   6162  N N   . CYS B 1 327 ? -67.512 48.073  9.323  1.00 96.51  ? 335 CYS B N   1 
ATOM   6163  C CA  . CYS B 1 327 ? -66.696 49.258  9.153  1.00 95.33  ? 335 CYS B CA  1 
ATOM   6164  C C   . CYS B 1 327 ? -66.368 49.454  7.669  1.00 115.27 ? 335 CYS B C   1 
ATOM   6165  O O   . CYS B 1 327 ? -66.496 50.564  7.156  1.00 151.20 ? 335 CYS B O   1 
ATOM   6166  C CB  . CYS B 1 327 ? -65.447 49.144  10.017 1.00 91.49  ? 335 CYS B CB  1 
ATOM   6167  S SG  . CYS B 1 327 ? -64.382 50.589  9.818  1.00 106.70 ? 335 CYS B SG  1 
ATOM   6168  N N   . ARG B 1 328 ? -65.980 48.371  6.977  1.00 115.44 ? 336 ARG B N   1 
ATOM   6169  C CA  . ARG B 1 328 ? -65.639 48.469  5.565  1.00 117.73 ? 336 ARG B CA  1 
ATOM   6170  C C   . ARG B 1 328 ? -66.864 48.948  4.794  1.00 114.42 ? 336 ARG B C   1 
ATOM   6171  O O   . ARG B 1 328 ? -66.729 49.894  4.014  1.00 95.71  ? 336 ARG B O   1 
ATOM   6172  C CB  . ARG B 1 328 ? -65.060 47.205  4.926  1.00 93.53  ? 336 ARG B CB  1 
ATOM   6173  C CG  . ARG B 1 328 ? -63.706 46.819  5.487  1.00 113.00 ? 336 ARG B CG  1 
ATOM   6174  C CD  . ARG B 1 328 ? -63.153 45.702  4.601  1.00 110.62 ? 336 ARG B CD  1 
ATOM   6175  N NE  . ARG B 1 328 ? -62.277 44.767  5.322  1.00 98.45  ? 336 ARG B NE  1 
ATOM   6176  C CZ  . ARG B 1 328 ? -61.117 45.026  5.949  1.00 87.50  ? 336 ARG B CZ  1 
ATOM   6177  N NH1 . ARG B 1 328 ? -60.693 46.257  6.148  1.00 66.86  ? 336 ARG B NH1 1 
ATOM   6178  N NH2 . ARG B 1 328 ? -60.376 44.042  6.430  1.00 97.11  ? 336 ARG B NH2 1 
ATOM   6179  N N   . ALA B 1 329 ? -68.033 48.339  5.078  1.00 85.90  ? 337 ALA B N   1 
ATOM   6180  C CA  . ALA B 1 329 ? -69.279 48.671  4.397  1.00 103.98 ? 337 ALA B CA  1 
ATOM   6181  C C   . ALA B 1 329 ? -69.580 50.163  4.523  1.00 117.01 ? 337 ALA B C   1 
ATOM   6182  O O   . ALA B 1 329 ? -69.785 50.872  3.519  1.00 120.79 ? 337 ALA B O   1 
ATOM   6183  C CB  . ALA B 1 329 ? -70.433 47.839  4.922  1.00 76.00  ? 337 ALA B CB  1 
ATOM   6184  N N   . LEU B 1 330 ? -69.588 50.599  5.789  1.00 130.05 ? 338 LEU B N   1 
ATOM   6185  C CA  . LEU B 1 330 ? -69.825 51.994  6.128  1.00 116.26 ? 338 LEU B CA  1 
ATOM   6186  C C   . LEU B 1 330 ? -68.810 52.906  5.430  1.00 101.13 ? 338 LEU B C   1 
ATOM   6187  O O   . LEU B 1 330 ? -69.208 53.905  4.818  1.00 90.95  ? 338 LEU B O   1 
ATOM   6188  C CB  . LEU B 1 330 ? -69.787 52.133  7.645  1.00 101.17 ? 338 LEU B CB  1 
ATOM   6189  C CG  . LEU B 1 330 ? -69.796 53.560  8.183  1.00 88.92  ? 338 LEU B CG  1 
ATOM   6190  C CD1 . LEU B 1 330 ? -71.061 54.276  7.748  1.00 96.11  ? 338 LEU B CD1 1 
ATOM   6191  C CD2 . LEU B 1 330 ? -69.621 53.520  9.691  1.00 99.95  ? 338 LEU B CD2 1 
ATOM   6192  N N   . SER B 1 331 ? -67.514 52.538  5.498  1.00 74.42  ? 339 SER B N   1 
ATOM   6193  C CA  . SER B 1 331 ? -66.462 53.322  4.878  1.00 78.49  ? 339 SER B CA  1 
ATOM   6194  C C   . SER B 1 331 ? -66.730 53.425  3.382  1.00 103.49 ? 339 SER B C   1 
ATOM   6195  O O   . SER B 1 331 ? -66.725 54.507  2.781  1.00 109.03 ? 339 SER B O   1 
ATOM   6196  C CB  . SER B 1 331 ? -65.129 52.702  5.084  1.00 82.21  ? 339 SER B CB  1 
ATOM   6197  O OG  . SER B 1 331 ? -64.110 53.411  4.390  1.00 85.95  ? 339 SER B OG  1 
ATOM   6198  N N   . GLU B 1 332 ? -66.959 52.270  2.760  1.00 102.13 ? 340 GLU B N   1 
ATOM   6199  C CA  . GLU B 1 332 ? -67.088 52.250  1.318  1.00 101.17 ? 340 GLU B CA  1 
ATOM   6200  C C   . GLU B 1 332 ? -68.263 53.160  0.942  1.00 95.02  ? 340 GLU B C   1 
ATOM   6201  O O   . GLU B 1 332 ? -68.145 53.978  0.036  1.00 98.11  ? 340 GLU B O   1 
ATOM   6202  C CB  . GLU B 1 332 ? -67.133 50.767  0.942  1.00 81.99  ? 340 GLU B CB  1 
ATOM   6203  C CG  . GLU B 1 332 ? -66.390 50.423  -0.344 1.00 87.19  ? 340 GLU B CG  1 
ATOM   6204  C CD  . GLU B 1 332 ? -67.424 49.679  -1.195 1.00 104.45 ? 340 GLU B CD  1 
ATOM   6205  O OE1 . GLU B 1 332 ? -68.444 49.175  -0.623 1.00 73.37  ? 340 GLU B OE1 1 
ATOM   6206  O OE2 . GLU B 1 332 ? -67.251 49.670  -2.449 1.00 116.13 ? 340 GLU B OE2 1 
ATOM   6207  N N   . ALA B 1 333 ? -69.390 53.023  1.658  1.00 85.17  ? 341 ALA B N   1 
ATOM   6208  C CA  . ALA B 1 333 ? -70.608 53.760  1.363  1.00 85.87  ? 341 ALA B CA  1 
ATOM   6209  C C   . ALA B 1 333 ? -70.365 55.271  1.415  1.00 97.89  ? 341 ALA B C   1 
ATOM   6210  O O   . ALA B 1 333 ? -70.769 56.010  0.517  1.00 103.47 ? 341 ALA B O   1 
ATOM   6211  C CB  . ALA B 1 333 ? -71.709 53.321  2.303  1.00 92.39  ? 341 ALA B CB  1 
ATOM   6212  N N   . LEU B 1 334 ? -69.699 55.736  2.473  1.00 106.68 ? 342 LEU B N   1 
ATOM   6213  C CA  . LEU B 1 334 ? -69.432 57.162  2.598  1.00 118.95 ? 342 LEU B CA  1 
ATOM   6214  C C   . LEU B 1 334 ? -68.510 57.624  1.467  1.00 114.83 ? 342 LEU B C   1 
ATOM   6215  O O   . LEU B 1 334 ? -68.650 58.732  0.932  1.00 114.98 ? 342 LEU B O   1 
ATOM   6216  C CB  . LEU B 1 334 ? -68.869 57.485  3.982  1.00 84.87  ? 342 LEU B CB  1 
ATOM   6217  C CG  . LEU B 1 334 ? -69.868 57.242  5.108  1.00 76.11  ? 342 LEU B CG  1 
ATOM   6218  C CD1 . LEU B 1 334 ? -69.140 57.414  6.405  1.00 107.55 ? 342 LEU B CD1 1 
ATOM   6219  C CD2 . LEU B 1 334 ? -70.952 58.288  5.026  1.00 67.63  ? 342 LEU B CD2 1 
ATOM   6220  N N   . THR B 1 335 ? -67.564 56.752  1.101  1.00 84.76  ? 343 THR B N   1 
ATOM   6221  C CA  . THR B 1 335 ? -66.629 57.116  0.051  1.00 97.67  ? 343 THR B CA  1 
ATOM   6222  C C   . THR B 1 335 ? -67.396 57.302  -1.247 1.00 98.74  ? 343 THR B C   1 
ATOM   6223  O O   . THR B 1 335 ? -67.149 58.262  -1.966 1.00 88.37  ? 343 THR B O   1 
ATOM   6224  C CB  . THR B 1 335 ? -65.580 56.038  -0.205 1.00 80.40  ? 343 THR B CB  1 
ATOM   6225  O OG1 . THR B 1 335 ? -65.014 55.739  1.059  1.00 65.48  ? 343 THR B OG1 1 
ATOM   6226  C CG2 . THR B 1 335 ? -64.632 56.440  -1.330 1.00 51.53  ? 343 THR B CG2 1 
ATOM   6227  N N   . GLU B 1 336 ? -68.264 56.321  -1.540 1.00 86.49  ? 344 GLU B N   1 
ATOM   6228  C CA  . GLU B 1 336 ? -69.097 56.338  -2.723 1.00 100.26 ? 344 GLU B CA  1 
ATOM   6229  C C   . GLU B 1 336 ? -69.902 57.632  -2.772 1.00 119.38 ? 344 GLU B C   1 
ATOM   6230  O O   . GLU B 1 336 ? -70.136 58.149  -3.866 1.00 148.55 ? 344 GLU B O   1 
ATOM   6231  C CB  . GLU B 1 336 ? -69.921 55.056  -2.748 1.00 103.06 ? 344 GLU B CB  1 
ATOM   6232  C CG  . GLU B 1 336 ? -69.127 53.997  -3.498 1.00 103.26 ? 344 GLU B CG  1 
ATOM   6233  C CD  . GLU B 1 336 ? -69.732 52.624  -3.413 1.00 97.83  ? 344 GLU B CD  1 
ATOM   6234  O OE1 . GLU B 1 336 ? -70.912 52.457  -2.949 1.00 72.82  ? 344 GLU B OE1 1 
ATOM   6235  O OE2 . GLU B 1 336 ? -68.896 51.773  -3.815 1.00 83.77  ? 344 GLU B OE2 1 
ATOM   6236  N N   . LEU B 1 337 ? -70.277 58.091  -1.571 1.00 95.15  ? 345 LEU B N   1 
ATOM   6237  C CA  . LEU B 1 337 ? -71.040 59.316  -1.414 1.00 85.15  ? 345 LEU B CA  1 
ATOM   6238  C C   . LEU B 1 337 ? -70.144 60.550  -1.471 1.00 88.97  ? 345 LEU B C   1 
ATOM   6239  O O   . LEU B 1 337 ? -70.636 61.649  -1.223 1.00 100.43 ? 345 LEU B O   1 
ATOM   6240  C CB  . LEU B 1 337 ? -71.822 59.275  -0.103 1.00 73.86  ? 345 LEU B CB  1 
ATOM   6241  C CG  . LEU B 1 337 ? -73.161 58.543  -0.167 1.00 86.82  ? 345 LEU B CG  1 
ATOM   6242  C CD1 . LEU B 1 337 ? -73.593 57.968  1.171  1.00 103.08 ? 345 LEU B CD1 1 
ATOM   6243  C CD2 . LEU B 1 337 ? -74.142 59.625  -0.584 1.00 64.13  ? 345 LEU B CD2 1 
ATOM   6244  N N   . GLY B 1 338 ? -68.842 60.377  -1.718 1.00 78.08  ? 346 GLY B N   1 
ATOM   6245  C CA  . GLY B 1 338 ? -67.945 61.505  -1.895 1.00 69.83  ? 346 GLY B CA  1 
ATOM   6246  C C   . GLY B 1 338 ? -67.253 61.979  -0.613 1.00 87.83  ? 346 GLY B C   1 
ATOM   6247  O O   . GLY B 1 338 ? -66.563 63.006  -0.670 1.00 88.85  ? 346 GLY B O   1 
ATOM   6248  N N   . TYR B 1 339 ? -67.393 61.252  0.518  1.00 69.55  ? 347 TYR B N   1 
ATOM   6249  C CA  . TYR B 1 339 ? -66.700 61.673  1.726  1.00 61.07  ? 347 TYR B CA  1 
ATOM   6250  C C   . TYR B 1 339 ? -65.247 61.204  1.667  1.00 88.70  ? 347 TYR B C   1 
ATOM   6251  O O   . TYR B 1 339 ? -64.999 60.109  1.125  1.00 97.27  ? 347 TYR B O   1 
ATOM   6252  C CB  . TYR B 1 339 ? -67.371 61.037  2.940  1.00 69.13  ? 347 TYR B CB  1 
ATOM   6253  C CG  . TYR B 1 339 ? -68.707 61.653  3.327  1.00 80.33  ? 347 TYR B CG  1 
ATOM   6254  C CD1 . TYR B 1 339 ? -68.759 62.801  4.115  1.00 104.41 ? 347 TYR B CD1 1 
ATOM   6255  C CD2 . TYR B 1 339 ? -69.904 61.085  2.922  1.00 85.42  ? 347 TYR B CD2 1 
ATOM   6256  C CE1 . TYR B 1 339 ? -69.959 63.375  4.483  1.00 101.99 ? 347 TYR B CE1 1 
ATOM   6257  C CE2 . TYR B 1 339 ? -71.118 61.642  3.293  1.00 119.33 ? 347 TYR B CE2 1 
ATOM   6258  C CZ  . TYR B 1 339 ? -71.140 62.788  4.069  1.00 119.86 ? 347 TYR B CZ  1 
ATOM   6259  O OH  . TYR B 1 339 ? -72.340 63.315  4.475  1.00 107.26 ? 347 TYR B OH  1 
ATOM   6260  N N   . LYS B 1 340 ? -64.311 62.013  2.234  1.00 77.12  ? 348 LYS B N   1 
ATOM   6261  C CA  . LYS B 1 340 ? -62.948 61.513  2.400  1.00 83.24  ? 348 LYS B CA  1 
ATOM   6262  C C   . LYS B 1 340 ? -62.820 60.714  3.702  1.00 97.82  ? 348 LYS B C   1 
ATOM   6263  O O   . LYS B 1 340 ? -63.123 61.195  4.787  1.00 93.07  ? 348 LYS B O   1 
ATOM   6264  C CB  . LYS B 1 340 ? -61.780 62.486  2.249  1.00 74.45  ? 348 LYS B CB  1 
ATOM   6265  C CG  . LYS B 1 340 ? -60.470 61.675  2.192  1.00 71.14  ? 348 LYS B CG  1 
ATOM   6266  C CD  . LYS B 1 340 ? -59.202 62.452  2.561  1.00 86.74  ? 348 LYS B CD  1 
ATOM   6267  C CE  . LYS B 1 340 ? -57.838 61.998  2.039  1.00 91.12  ? 348 LYS B CE  1 
ATOM   6268  N NZ  . LYS B 1 340 ? -56.651 62.796  2.443  1.00 81.18  ? 348 LYS B NZ  1 
ATOM   6269  N N   . ILE B 1 341 ? -62.316 59.485  3.572  1.00 85.87  ? 349 ILE B N   1 
ATOM   6270  C CA  . ILE B 1 341 ? -62.001 58.671  4.729  1.00 76.58  ? 349 ILE B CA  1 
ATOM   6271  C C   . ILE B 1 341 ? -60.484 58.702  4.866  1.00 90.21  ? 349 ILE B C   1 
ATOM   6272  O O   . ILE B 1 341 ? -59.794 58.245  3.958  1.00 75.85  ? 349 ILE B O   1 
ATOM   6273  C CB  . ILE B 1 341 ? -62.509 57.225  4.532  1.00 78.06  ? 349 ILE B CB  1 
ATOM   6274  C CG1 . ILE B 1 341 ? -64.007 57.153  4.448  1.00 88.66  ? 349 ILE B CG1 1 
ATOM   6275  C CG2 . ILE B 1 341 ? -62.026 56.318  5.656  1.00 111.98 ? 349 ILE B CG2 1 
ATOM   6276  C CD1 . ILE B 1 341 ? -64.720 57.763  5.625  1.00 78.42  ? 349 ILE B CD1 1 
ATOM   6277  N N   . VAL B 1 342 ? -59.981 59.200  6.002  1.00 112.29 ? 350 VAL B N   1 
ATOM   6278  C CA  . VAL B 1 342 ? -58.544 59.327  6.194  1.00 103.11 ? 350 VAL B CA  1 
ATOM   6279  C C   . VAL B 1 342 ? -57.903 57.954  6.022  1.00 104.99 ? 350 VAL B C   1 
ATOM   6280  O O   . VAL B 1 342 ? -58.379 56.973  6.594  1.00 113.49 ? 350 VAL B O   1 
ATOM   6281  C CB  . VAL B 1 342 ? -58.132 59.917  7.551  1.00 95.98  ? 350 VAL B CB  1 
ATOM   6282  C CG1 . VAL B 1 342 ? -56.627 60.035  7.528  1.00 95.54  ? 350 VAL B CG1 1 
ATOM   6283  C CG2 . VAL B 1 342 ? -58.732 61.295  7.844  1.00 80.53  ? 350 VAL B CG2 1 
ATOM   6284  N N   . THR B 1 343 ? -56.810 57.915  5.254  1.00 87.77  ? 351 THR B N   1 
ATOM   6285  C CA  . THR B 1 343 ? -56.116 56.671  4.939  1.00 91.24  ? 351 THR B CA  1 
ATOM   6286  C C   . THR B 1 343 ? -56.877 55.843  3.894  1.00 95.19  ? 351 THR B C   1 
ATOM   6287  O O   . THR B 1 343 ? -56.386 54.808  3.448  1.00 88.85  ? 351 THR B O   1 
ATOM   6288  C CB  . THR B 1 343 ? -55.817 55.839  6.180  1.00 84.62  ? 351 THR B CB  1 
ATOM   6289  O OG1 . THR B 1 343 ? -54.988 54.807  5.675  1.00 106.32 ? 351 THR B OG1 1 
ATOM   6290  C CG2 . THR B 1 343 ? -57.024 55.093  6.718  1.00 58.67  ? 351 THR B CG2 1 
ATOM   6291  N N   . GLY B 1 344 ? -58.070 56.278  3.491  1.00 87.15  ? 352 GLY B N   1 
ATOM   6292  C CA  . GLY B 1 344 ? -58.729 55.593  2.389  1.00 83.01  ? 352 GLY B CA  1 
ATOM   6293  C C   . GLY B 1 344 ? -59.791 54.629  2.911  1.00 98.75  ? 352 GLY B C   1 
ATOM   6294  O O   . GLY B 1 344 ? -60.735 54.263  2.244  1.00 131.03 ? 352 GLY B O   1 
ATOM   6295  N N   . GLY B 1 345 ? -59.648 54.228  4.157  1.00 94.09  ? 353 GLY B N   1 
ATOM   6296  C CA  . GLY B 1 345 ? -60.521 53.196  4.669  1.00 78.35  ? 353 GLY B CA  1 
ATOM   6297  C C   . GLY B 1 345 ? -59.988 52.710  6.015  1.00 76.08  ? 353 GLY B C   1 
ATOM   6298  O O   . GLY B 1 345 ? -59.318 53.439  6.748  1.00 116.91 ? 353 GLY B O   1 
ATOM   6299  N N   . SER B 1 346 ? -60.208 51.425  6.273  1.00 67.20  ? 354 SER B N   1 
ATOM   6300  C CA  . SER B 1 346 ? -60.023 50.852  7.581  1.00 65.40  ? 354 SER B CA  1 
ATOM   6301  C C   . SER B 1 346 ? -59.696 49.365  7.537  1.00 66.48  ? 354 SER B C   1 
ATOM   6302  O O   . SER B 1 346 ? -60.242 48.607  6.749  1.00 72.65  ? 354 SER B O   1 
ATOM   6303  C CB  . SER B 1 346 ? -61.227 51.109  8.443  1.00 72.98  ? 354 SER B CB  1 
ATOM   6304  O OG  . SER B 1 346 ? -60.969 50.544  9.723  1.00 76.81  ? 354 SER B OG  1 
ATOM   6305  N N   . ASP B 1 347 ? -58.831 48.954  8.463  1.00 75.22  ? 355 ASP B N   1 
ATOM   6306  C CA  . ASP B 1 347 ? -58.495 47.565  8.703  1.00 74.82  ? 355 ASP B CA  1 
ATOM   6307  C C   . ASP B 1 347 ? -59.196 47.103  9.969  1.00 86.28  ? 355 ASP B C   1 
ATOM   6308  O O   . ASP B 1 347 ? -59.089 45.929  10.310 1.00 126.10 ? 355 ASP B O   1 
ATOM   6309  C CB  . ASP B 1 347 ? -56.998 47.401  8.900  1.00 66.79  ? 355 ASP B CB  1 
ATOM   6310  C CG  . ASP B 1 347 ? -56.160 47.945  7.754  1.00 83.53  ? 355 ASP B CG  1 
ATOM   6311  O OD1 . ASP B 1 347 ? -56.663 47.791  6.607  1.00 66.34  ? 355 ASP B OD1 1 
ATOM   6312  O OD2 . ASP B 1 347 ? -55.034 48.478  8.020  1.00 96.65  ? 355 ASP B OD2 1 
ATOM   6313  N N   . ASN B 1 348 ? -59.917 48.014  10.641 1.00 65.69  ? 356 ASN B N   1 
ATOM   6314  C CA  . ASN B 1 348 ? -60.439 47.766  11.982 1.00 88.80  ? 356 ASN B CA  1 
ATOM   6315  C C   . ASN B 1 348 ? -61.883 48.250  12.103 1.00 107.41 ? 356 ASN B C   1 
ATOM   6316  O O   . ASN B 1 348 ? -62.638 48.262  11.131 1.00 147.30 ? 356 ASN B O   1 
ATOM   6317  C CB  . ASN B 1 348 ? -59.562 48.385  13.074 1.00 98.47  ? 356 ASN B CB  1 
ATOM   6318  C CG  . ASN B 1 348 ? -59.221 49.849  12.852 1.00 111.47 ? 356 ASN B CG  1 
ATOM   6319  O OD1 . ASN B 1 348 ? -60.079 50.704  12.526 1.00 94.41  ? 356 ASN B OD1 1 
ATOM   6320  N ND2 . ASN B 1 348 ? -57.940 50.113  13.039 1.00 85.97  ? 356 ASN B ND2 1 
ATOM   6321  N N   . HIS B 1 349 ? -62.234 48.695  13.313 1.00 81.22  ? 357 HIS B N   1 
ATOM   6322  C CA  . HIS B 1 349 ? -63.613 48.983  13.672 1.00 100.24 ? 357 HIS B CA  1 
ATOM   6323  C C   . HIS B 1 349 ? -64.002 50.453  13.474 1.00 111.70 ? 357 HIS B C   1 
ATOM   6324  O O   . HIS B 1 349 ? -65.160 50.823  13.718 1.00 96.64  ? 357 HIS B O   1 
ATOM   6325  C CB  . HIS B 1 349 ? -63.806 48.623  15.145 1.00 84.07  ? 357 HIS B CB  1 
ATOM   6326  C CG  . HIS B 1 349 ? -62.889 49.398  16.020 1.00 95.49  ? 357 HIS B CG  1 
ATOM   6327  N ND1 . HIS B 1 349 ? -61.525 49.535  15.828 1.00 90.64  ? 357 HIS B ND1 1 
ATOM   6328  C CD2 . HIS B 1 349 ? -63.171 50.094  17.109 1.00 114.51 ? 357 HIS B CD2 1 
ATOM   6329  C CE1 . HIS B 1 349 ? -60.998 50.287  16.791 1.00 102.59 ? 357 HIS B CE1 1 
ATOM   6330  N NE2 . HIS B 1 349 ? -61.985 50.671  17.570 1.00 105.91 ? 357 HIS B NE2 1 
ATOM   6331  N N   . LEU B 1 350 ? -63.049 51.310  13.072 1.00 92.48  ? 358 LEU B N   1 
ATOM   6332  C CA  . LEU B 1 350 ? -63.372 52.733  12.997 1.00 86.17  ? 358 LEU B CA  1 
ATOM   6333  C C   . LEU B 1 350 ? -62.846 53.361  11.716 1.00 86.55  ? 358 LEU B C   1 
ATOM   6334  O O   . LEU B 1 350 ? -61.943 52.820  11.075 1.00 97.48  ? 358 LEU B O   1 
ATOM   6335  C CB  . LEU B 1 350 ? -62.927 53.554  14.214 1.00 75.27  ? 358 LEU B CB  1 
ATOM   6336  C CG  . LEU B 1 350 ? -61.415 53.675  14.432 1.00 69.57  ? 358 LEU B CG  1 
ATOM   6337  C CD1 . LEU B 1 350 ? -60.665 54.657  13.513 1.00 59.03  ? 358 LEU B CD1 1 
ATOM   6338  C CD2 . LEU B 1 350 ? -61.126 53.924  15.890 1.00 60.68  ? 358 LEU B CD2 1 
ATOM   6339  N N   . ILE B 1 351 ? -63.381 54.559  11.407 1.00 83.18  ? 359 ILE B N   1 
ATOM   6340  C CA  . ILE B 1 351 ? -62.871 55.393  10.321 1.00 91.54  ? 359 ILE B CA  1 
ATOM   6341  C C   . ILE B 1 351 ? -62.816 56.834  10.793 1.00 87.66  ? 359 ILE B C   1 
ATOM   6342  O O   . ILE B 1 351 ? -63.590 57.224  11.691 1.00 77.17  ? 359 ILE B O   1 
ATOM   6343  C CB  . ILE B 1 351 ? -63.764 55.279  9.071  1.00 92.79  ? 359 ILE B CB  1 
ATOM   6344  C CG1 . ILE B 1 351 ? -65.251 55.537  9.466  1.00 73.16  ? 359 ILE B CG1 1 
ATOM   6345  C CG2 . ILE B 1 351 ? -63.536 53.929  8.344  1.00 74.51  ? 359 ILE B CG2 1 
ATOM   6346  C CD1 . ILE B 1 351 ? -66.254 55.259  8.371  1.00 89.41  ? 359 ILE B CD1 1 
ATOM   6347  N N   . LEU B 1 352 ? -61.906 57.602  10.179 1.00 75.29  ? 360 LEU B N   1 
ATOM   6348  C CA  . LEU B 1 352 ? -61.907 59.028  10.490 1.00 76.15  ? 360 LEU B CA  1 
ATOM   6349  C C   . LEU B 1 352 ? -62.383 59.777  9.250  1.00 85.73  ? 360 LEU B C   1 
ATOM   6350  O O   . LEU B 1 352 ? -61.696 59.749  8.217  1.00 68.84  ? 360 LEU B O   1 
ATOM   6351  C CB  . LEU B 1 352 ? -60.527 59.514  10.913 1.00 78.09  ? 360 LEU B CB  1 
ATOM   6352  C CG  . LEU B 1 352 ? -60.416 61.003  11.274 1.00 88.27  ? 360 LEU B CG  1 
ATOM   6353  C CD1 . LEU B 1 352 ? -61.432 61.368  12.309 1.00 92.52  ? 360 LEU B CD1 1 
ATOM   6354  C CD2 . LEU B 1 352 ? -59.091 61.360  11.867 1.00 67.47  ? 360 LEU B CD2 1 
ATOM   6355  N N   . VAL B 1 353 ? -63.562 60.404  9.359  1.00 75.83  ? 361 VAL B N   1 
ATOM   6356  C CA  . VAL B 1 353 ? -64.155 61.030  8.185  1.00 83.07  ? 361 VAL B CA  1 
ATOM   6357  C C   . VAL B 1 353 ? -63.793 62.510  8.163  1.00 100.37 ? 361 VAL B C   1 
ATOM   6358  O O   . VAL B 1 353 ? -64.195 63.254  9.060  1.00 105.11 ? 361 VAL B O   1 
ATOM   6359  C CB  . VAL B 1 353 ? -65.683 60.929  8.108  1.00 67.15  ? 361 VAL B CB  1 
ATOM   6360  C CG1 . VAL B 1 353 ? -66.173 61.561  6.817  1.00 56.18  ? 361 VAL B CG1 1 
ATOM   6361  C CG2 . VAL B 1 353 ? -66.195 59.498  8.259  1.00 58.52  ? 361 VAL B CG2 1 
ATOM   6362  N N   . ASP B 1 354 ? -63.099 62.914  7.094  1.00 105.37 ? 362 ASP B N   1 
ATOM   6363  C CA  . ASP B 1 354 ? -62.669 64.282  6.916  1.00 91.18  ? 362 ASP B CA  1 
ATOM   6364  C C   . ASP B 1 354 ? -63.832 65.102  6.359  1.00 107.65 ? 362 ASP B C   1 
ATOM   6365  O O   . ASP B 1 354 ? -64.009 65.174  5.151  1.00 95.68  ? 362 ASP B O   1 
ATOM   6366  C CB  . ASP B 1 354 ? -61.498 64.325  5.950  1.00 72.40  ? 362 ASP B CB  1 
ATOM   6367  C CG  . ASP B 1 354 ? -60.686 65.599  6.044  1.00 81.42  ? 362 ASP B CG  1 
ATOM   6368  O OD1 . ASP B 1 354 ? -61.292 66.634  6.372  1.00 94.41  ? 362 ASP B OD1 1 
ATOM   6369  O OD2 . ASP B 1 354 ? -59.471 65.532  5.803  1.00 81.75  ? 362 ASP B OD2 1 
ATOM   6370  N N   . LEU B 1 355 ? -64.625 65.715  7.238  1.00 100.58 ? 363 LEU B N   1 
ATOM   6371  C CA  . LEU B 1 355 ? -65.770 66.491  6.789  1.00 98.24  ? 363 LEU B CA  1 
ATOM   6372  C C   . LEU B 1 355 ? -65.352 67.657  5.879  1.00 100.60 ? 363 LEU B C   1 
ATOM   6373  O O   . LEU B 1 355 ? -66.214 68.312  5.295  1.00 103.55 ? 363 LEU B O   1 
ATOM   6374  C CB  . LEU B 1 355 ? -66.653 66.969  7.944  1.00 66.52  ? 363 LEU B CB  1 
ATOM   6375  C CG  . LEU B 1 355 ? -67.507 65.892  8.612  1.00 76.83  ? 363 LEU B CG  1 
ATOM   6376  C CD1 . LEU B 1 355 ? -68.401 66.614  9.623  1.00 118.38 ? 363 LEU B CD1 1 
ATOM   6377  C CD2 . LEU B 1 355 ? -68.312 65.001  7.660  1.00 64.04  ? 363 LEU B CD2 1 
ATOM   6378  N N   . ARG B 1 356 ? -64.050 67.958  5.742  1.00 83.84  ? 364 ARG B N   1 
ATOM   6379  C CA  . ARG B 1 356 ? -63.688 69.051  4.846  1.00 107.83 ? 364 ARG B CA  1 
ATOM   6380  C C   . ARG B 1 356 ? -64.129 68.778  3.400  1.00 106.86 ? 364 ARG B C   1 
ATOM   6381  O O   . ARG B 1 356 ? -64.466 69.705  2.682  1.00 106.60 ? 364 ARG B O   1 
ATOM   6382  C CB  . ARG B 1 356 ? -62.200 69.422  4.916  1.00 109.72 ? 364 ARG B CB  1 
ATOM   6383  C CG  . ARG B 1 356 ? -61.846 70.228  6.153  1.00 97.27  ? 364 ARG B CG  1 
ATOM   6384  C CD  . ARG B 1 356 ? -60.341 70.442  6.239  1.00 91.02  ? 364 ARG B CD  1 
ATOM   6385  N NE  . ARG B 1 356 ? -59.643 69.190  6.558  1.00 92.27  ? 364 ARG B NE  1 
ATOM   6386  C CZ  . ARG B 1 356 ? -58.324 69.028  6.729  1.00 111.13 ? 364 ARG B CZ  1 
ATOM   6387  N NH1 . ARG B 1 356 ? -57.491 70.033  6.887  1.00 121.62 ? 364 ARG B NH1 1 
ATOM   6388  N NH2 . ARG B 1 356 ? -57.767 67.837  6.733  1.00 130.81 ? 364 ARG B NH2 1 
ATOM   6389  N N   . SER B 1 357 ? -64.137 67.508  2.983  1.00 119.96 ? 365 SER B N   1 
ATOM   6390  C CA  . SER B 1 357 ? -64.591 67.064  1.675  1.00 76.53  ? 365 SER B CA  1 
ATOM   6391  C C   . SER B 1 357 ? -66.068 67.423  1.451  1.00 80.64  ? 365 SER B C   1 
ATOM   6392  O O   . SER B 1 357 ? -66.542 67.387  0.328  1.00 119.84 ? 365 SER B O   1 
ATOM   6393  C CB  . SER B 1 357 ? -64.397 65.545  1.554  1.00 82.36  ? 365 SER B CB  1 
ATOM   6394  O OG  . SER B 1 357 ? -65.150 64.847  2.551  1.00 82.86  ? 365 SER B OG  1 
ATOM   6395  N N   . LYS B 1 358 ? -66.807 67.793  2.491  1.00 68.69  ? 366 LYS B N   1 
ATOM   6396  C CA  . LYS B 1 358 ? -68.178 68.257  2.308  1.00 100.51 ? 366 LYS B CA  1 
ATOM   6397  C C   . LYS B 1 358 ? -68.331 69.750  2.647  1.00 108.62 ? 366 LYS B C   1 
ATOM   6398  O O   . LYS B 1 358 ? -69.459 70.250  2.606  1.00 93.53  ? 366 LYS B O   1 
ATOM   6399  C CB  . LYS B 1 358 ? -69.142 67.416  3.173  1.00 95.25  ? 366 LYS B CB  1 
ATOM   6400  C CG  . LYS B 1 358 ? -69.884 66.218  2.609  1.00 84.69  ? 366 LYS B CG  1 
ATOM   6401  C CD  . LYS B 1 358 ? -69.349 65.653  1.299  1.00 105.32 ? 366 LYS B CD  1 
ATOM   6402  C CE  . LYS B 1 358 ? -69.898 64.348  0.817  1.00 117.50 ? 366 LYS B CE  1 
ATOM   6403  N NZ  . LYS B 1 358 ? -69.682 64.246  -0.630 1.00 114.37 ? 366 LYS B NZ  1 
ATOM   6404  N N   . GLY B 1 359 ? -67.217 70.431  3.005  1.00 95.11  ? 367 GLY B N   1 
ATOM   6405  C CA  . GLY B 1 359 ? -67.186 71.814  3.483  1.00 77.68  ? 367 GLY B CA  1 
ATOM   6406  C C   . GLY B 1 359 ? -67.901 72.038  4.829  1.00 94.99  ? 367 GLY B C   1 
ATOM   6407  O O   . GLY B 1 359 ? -68.764 72.922  4.982  1.00 66.50  ? 367 GLY B O   1 
ATOM   6408  N N   . THR B 1 360 ? -67.485 71.288  5.854  1.00 98.38  ? 368 THR B N   1 
ATOM   6409  C CA  . THR B 1 360 ? -67.936 71.604  7.209  1.00 92.20  ? 368 THR B CA  1 
ATOM   6410  C C   . THR B 1 360 ? -66.937 70.979  8.166  1.00 97.10  ? 368 THR B C   1 
ATOM   6411  O O   . THR B 1 360 ? -65.944 70.473  7.679  1.00 120.94 ? 368 THR B O   1 
ATOM   6412  C CB  . THR B 1 360 ? -69.361 71.101  7.446  1.00 99.91  ? 368 THR B CB  1 
ATOM   6413  O OG1 . THR B 1 360 ? -69.806 71.605  8.708  1.00 83.72  ? 368 THR B OG1 1 
ATOM   6414  C CG2 . THR B 1 360 ? -69.478 69.590  7.380  1.00 124.83 ? 368 THR B CG2 1 
ATOM   6415  N N   . ASP B 1 361 ? -67.231 70.959  9.474  1.00 97.93  ? 369 ASP B N   1 
ATOM   6416  C CA  . ASP B 1 361 ? -66.372 70.386  10.494 1.00 86.59  ? 369 ASP B CA  1 
ATOM   6417  C C   . ASP B 1 361 ? -67.153 69.412  11.396 1.00 101.22 ? 369 ASP B C   1 
ATOM   6418  O O   . ASP B 1 361 ? -68.382 69.495  11.572 1.00 94.33  ? 369 ASP B O   1 
ATOM   6419  C CB  . ASP B 1 361 ? -65.731 71.515  11.284 1.00 68.76  ? 369 ASP B CB  1 
ATOM   6420  C CG  . ASP B 1 361 ? -66.725 72.337  12.099 1.00 97.50  ? 369 ASP B CG  1 
ATOM   6421  O OD1 . ASP B 1 361 ? -67.055 71.945  13.247 1.00 89.46  ? 369 ASP B OD1 1 
ATOM   6422  O OD2 . ASP B 1 361 ? -67.207 73.359  11.572 1.00 109.55 ? 369 ASP B OD2 1 
ATOM   6423  N N   . GLY B 1 362 ? -66.402 68.481  12.002 1.00 90.38  ? 370 GLY B N   1 
ATOM   6424  C CA  . GLY B 1 362 ? -66.974 67.534  12.948 1.00 101.91 ? 370 GLY B CA  1 
ATOM   6425  C C   . GLY B 1 362 ? -67.540 68.225  14.194 1.00 102.42 ? 370 GLY B C   1 
ATOM   6426  O O   . GLY B 1 362 ? -68.326 67.641  14.938 1.00 83.00  ? 370 GLY B O   1 
ATOM   6427  N N   . GLY B 1 363 ? -67.075 69.452  14.462 1.00 83.01  ? 371 GLY B N   1 
ATOM   6428  C CA  . GLY B 1 363 ? -67.470 70.185  15.648 1.00 88.33  ? 371 GLY B CA  1 
ATOM   6429  C C   . GLY B 1 363 ? -68.980 70.356  15.620 1.00 101.80 ? 371 GLY B C   1 
ATOM   6430  O O   . GLY B 1 363 ? -69.671 70.089  16.610 1.00 109.48 ? 371 GLY B O   1 
ATOM   6431  N N   . ARG B 1 364 ? -69.446 70.770  14.432 1.00 107.61 ? 372 ARG B N   1 
ATOM   6432  C CA  . ARG B 1 364 ? -70.838 71.088  14.154 1.00 99.65  ? 372 ARG B CA  1 
ATOM   6433  C C   . ARG B 1 364 ? -71.606 69.784  13.994 1.00 103.60 ? 372 ARG B C   1 
ATOM   6434  O O   . ARG B 1 364 ? -72.637 69.593  14.652 1.00 82.39  ? 372 ARG B O   1 
ATOM   6435  C CB  . ARG B 1 364 ? -70.909 71.921  12.869 1.00 76.13  ? 372 ARG B CB  1 
ATOM   6436  C CG  . ARG B 1 364 ? -70.414 73.338  13.087 1.00 75.03  ? 372 ARG B CG  1 
ATOM   6437  C CD  . ARG B 1 364 ? -70.140 74.159  11.817 1.00 71.68  ? 372 ARG B CD  1 
ATOM   6438  N NE  . ARG B 1 364 ? -69.285 75.289  12.217 1.00 68.32  ? 372 ARG B NE  1 
ATOM   6439  C CZ  . ARG B 1 364 ? -69.742 76.380  12.861 1.00 94.69  ? 372 ARG B CZ  1 
ATOM   6440  N NH1 . ARG B 1 364 ? -71.030 76.699  12.884 1.00 91.32  ? 372 ARG B NH1 1 
ATOM   6441  N NH2 . ARG B 1 364 ? -68.891 77.177  13.482 1.00 115.43 ? 372 ARG B NH2 1 
ATOM   6442  N N   . ALA B 1 365 ? -71.053 68.919  13.127 1.00 97.54  ? 373 ALA B N   1 
ATOM   6443  C CA  . ALA B 1 365 ? -71.726 67.704  12.713 1.00 93.95  ? 373 ALA B CA  1 
ATOM   6444  C C   . ALA B 1 365 ? -72.047 66.867  13.945 1.00 103.96 ? 373 ALA B C   1 
ATOM   6445  O O   . ALA B 1 365 ? -73.175 66.439  14.146 1.00 107.50 ? 373 ALA B O   1 
ATOM   6446  C CB  . ALA B 1 365 ? -70.873 66.961  11.733 1.00 79.09  ? 373 ALA B CB  1 
ATOM   6447  N N   . GLU B 1 366 ? -71.043 66.683  14.803 1.00 89.72  ? 374 GLU B N   1 
ATOM   6448  C CA  . GLU B 1 366 ? -71.188 65.996  16.071 1.00 75.46  ? 374 GLU B CA  1 
ATOM   6449  C C   . GLU B 1 366 ? -72.532 66.355  16.701 1.00 95.47  ? 374 GLU B C   1 
ATOM   6450  O O   . GLU B 1 366 ? -73.351 65.466  16.948 1.00 106.77 ? 374 GLU B O   1 
ATOM   6451  C CB  . GLU B 1 366 ? -70.042 66.500  16.954 1.00 94.82  ? 374 GLU B CB  1 
ATOM   6452  C CG  . GLU B 1 366 ? -70.072 66.029  18.401 1.00 100.35 ? 374 GLU B CG  1 
ATOM   6453  C CD  . GLU B 1 366 ? -68.792 66.451  19.092 1.00 118.53 ? 374 GLU B CD  1 
ATOM   6454  O OE1 . GLU B 1 366 ? -68.477 67.646  19.229 1.00 148.54 ? 374 GLU B OE1 1 
ATOM   6455  O OE2 . GLU B 1 366 ? -68.104 65.528  19.515 1.00 133.44 ? 374 GLU B OE2 1 
ATOM   6456  N N   . LYS B 1 367 ? -72.763 67.668  16.885 1.00 107.03 ? 375 LYS B N   1 
ATOM   6457  C CA  . LYS B 1 367 ? -73.878 68.181  17.677 1.00 120.63 ? 375 LYS B CA  1 
ATOM   6458  C C   . LYS B 1 367 ? -75.235 67.899  17.022 1.00 120.03 ? 375 LYS B C   1 
ATOM   6459  O O   . LYS B 1 367 ? -76.167 67.511  17.729 1.00 90.15  ? 375 LYS B O   1 
ATOM   6460  C CB  . LYS B 1 367 ? -73.701 69.680  17.958 1.00 110.71 ? 375 LYS B CB  1 
ATOM   6461  C CG  . LYS B 1 367 ? -72.600 70.065  18.923 1.00 115.07 ? 375 LYS B CG  1 
ATOM   6462  C CD  . LYS B 1 367 ? -72.530 69.193  20.171 1.00 124.20 ? 375 LYS B CD  1 
ATOM   6463  C CE  . LYS B 1 367 ? -71.560 69.694  21.199 1.00 105.77 ? 375 LYS B CE  1 
ATOM   6464  N NZ  . LYS B 1 367 ? -71.061 68.614  22.075 1.00 93.56  ? 375 LYS B NZ  1 
ATOM   6465  N N   . VAL B 1 368 ? -75.320 68.089  15.695 1.00 116.26 ? 376 VAL B N   1 
ATOM   6466  C CA  . VAL B 1 368 ? -76.481 67.800  14.872 1.00 104.13 ? 376 VAL B CA  1 
ATOM   6467  C C   . VAL B 1 368 ? -76.824 66.322  15.015 1.00 102.03 ? 376 VAL B C   1 
ATOM   6468  O O   . VAL B 1 368 ? -77.924 65.954  15.443 1.00 113.51 ? 376 VAL B O   1 
ATOM   6469  C CB  . VAL B 1 368 ? -76.113 68.045  13.389 1.00 103.75 ? 376 VAL B CB  1 
ATOM   6470  C CG1 . VAL B 1 368 ? -77.260 67.681  12.435 1.00 81.53  ? 376 VAL B CG1 1 
ATOM   6471  C CG2 . VAL B 1 368 ? -75.502 69.409  13.082 1.00 95.70  ? 376 VAL B CG2 1 
ATOM   6472  N N   . LEU B 1 369 ? -75.872 65.483  14.563 1.00 90.31  ? 377 LEU B N   1 
ATOM   6473  C CA  . LEU B 1 369 ? -76.071 64.043  14.456 1.00 73.49  ? 377 LEU B CA  1 
ATOM   6474  C C   . LEU B 1 369 ? -76.558 63.586  15.818 1.00 84.33  ? 377 LEU B C   1 
ATOM   6475  O O   . LEU B 1 369 ? -77.450 62.723  15.895 1.00 62.99  ? 377 LEU B O   1 
ATOM   6476  C CB  . LEU B 1 369 ? -74.794 63.301  14.094 1.00 74.08  ? 377 LEU B CB  1 
ATOM   6477  C CG  . LEU B 1 369 ? -74.257 63.496  12.675 1.00 83.38  ? 377 LEU B CG  1 
ATOM   6478  C CD1 . LEU B 1 369 ? -72.726 63.434  12.538 1.00 73.54  ? 377 LEU B CD1 1 
ATOM   6479  C CD2 . LEU B 1 369 ? -74.893 62.349  11.955 1.00 77.91  ? 377 LEU B CD2 1 
ATOM   6480  N N   . GLU B 1 370 ? -75.979 64.237  16.858 1.00 76.09  ? 378 GLU B N   1 
ATOM   6481  C CA  . GLU B 1 370 ? -76.332 63.914  18.233 1.00 79.42  ? 378 GLU B CA  1 
ATOM   6482  C C   . GLU B 1 370 ? -77.824 64.154  18.437 1.00 102.85 ? 378 GLU B C   1 
ATOM   6483  O O   . GLU B 1 370 ? -78.501 63.334  19.072 1.00 109.04 ? 378 GLU B O   1 
ATOM   6484  C CB  . GLU B 1 370 ? -75.462 64.681  19.226 1.00 59.53  ? 378 GLU B CB  1 
ATOM   6485  C CG  . GLU B 1 370 ? -75.948 64.632  20.676 1.00 61.90  ? 378 GLU B CG  1 
ATOM   6486  C CD  . GLU B 1 370 ? -75.085 65.409  21.670 1.00 77.69  ? 378 GLU B CD  1 
ATOM   6487  O OE1 . GLU B 1 370 ? -74.202 66.333  21.391 1.00 71.23  ? 378 GLU B OE1 1 
ATOM   6488  O OE2 . GLU B 1 370 ? -75.370 64.981  22.820 1.00 54.21  ? 378 GLU B OE2 1 
ATOM   6489  N N   . ALA B 1 371 ? -78.288 65.310  17.941 1.00 91.24  ? 379 ALA B N   1 
ATOM   6490  C CA  . ALA B 1 371 ? -79.663 65.736  18.124 1.00 88.10  ? 379 ALA B CA  1 
ATOM   6491  C C   . ALA B 1 371 ? -80.598 64.823  17.326 1.00 105.12 ? 379 ALA B C   1 
ATOM   6492  O O   . ALA B 1 371 ? -81.804 64.818  17.564 1.00 141.91 ? 379 ALA B O   1 
ATOM   6493  C CB  . ALA B 1 371 ? -79.800 67.188  17.744 1.00 84.02  ? 379 ALA B CB  1 
ATOM   6494  N N   . CYS B 1 372 ? -80.036 64.033  16.399 1.00 79.51  ? 380 CYS B N   1 
ATOM   6495  C CA  . CYS B 1 372 ? -80.835 63.097  15.622 1.00 84.17  ? 380 CYS B CA  1 
ATOM   6496  C C   . CYS B 1 372 ? -80.651 61.676  16.145 1.00 105.73 ? 380 CYS B C   1 
ATOM   6497  O O   . CYS B 1 372 ? -80.995 60.714  15.443 1.00 118.39 ? 380 CYS B O   1 
ATOM   6498  C CB  . CYS B 1 372 ? -80.459 63.061  14.151 1.00 68.33  ? 380 CYS B CB  1 
ATOM   6499  S SG  . CYS B 1 372 ? -80.181 64.698  13.476 1.00 72.36  ? 380 CYS B SG  1 
ATOM   6500  N N   . SER B 1 373 ? -80.099 61.560  17.368 1.00 86.90  ? 381 SER B N   1 
ATOM   6501  C CA  . SER B 1 373 ? -79.915 60.268  18.019 1.00 85.80  ? 381 SER B CA  1 
ATOM   6502  C C   . SER B 1 373 ? -78.864 59.402  17.334 1.00 93.78  ? 381 SER B C   1 
ATOM   6503  O O   . SER B 1 373 ? -78.889 58.178  17.533 1.00 95.13  ? 381 SER B O   1 
ATOM   6504  C CB  . SER B 1 373 ? -81.187 59.487  18.125 1.00 77.17  ? 381 SER B CB  1 
ATOM   6505  O OG  . SER B 1 373 ? -82.116 60.260  18.872 1.00 134.37 ? 381 SER B OG  1 
ATOM   6506  N N   . ILE B 1 374 ? -77.958 60.041  16.578 1.00 83.02  ? 382 ILE B N   1 
ATOM   6507  C CA  . ILE B 1 374 ? -76.819 59.364  15.990 1.00 96.06  ? 382 ILE B CA  1 
ATOM   6508  C C   . ILE B 1 374 ? -75.598 59.812  16.783 1.00 103.03 ? 382 ILE B C   1 
ATOM   6509  O O   . ILE B 1 374 ? -75.106 60.917  16.591 1.00 126.67 ? 382 ILE B O   1 
ATOM   6510  C CB  . ILE B 1 374 ? -76.678 59.701  14.492 1.00 100.33 ? 382 ILE B CB  1 
ATOM   6511  C CG1 . ILE B 1 374 ? -77.948 59.416  13.731 1.00 92.31  ? 382 ILE B CG1 1 
ATOM   6512  C CG2 . ILE B 1 374 ? -75.494 58.947  13.877 1.00 84.44  ? 382 ILE B CG2 1 
ATOM   6513  C CD1 . ILE B 1 374 ? -77.802 59.704  12.245 1.00 88.86  ? 382 ILE B CD1 1 
ATOM   6514  N N   . ALA B 1 375 ? -75.110 58.943  17.664 1.00 88.01  ? 383 ALA B N   1 
ATOM   6515  C CA  . ALA B 1 375 ? -73.985 59.305  18.507 1.00 87.39  ? 383 ALA B CA  1 
ATOM   6516  C C   . ALA B 1 375 ? -72.681 59.022  17.776 1.00 86.08  ? 383 ALA B C   1 
ATOM   6517  O O   . ALA B 1 375 ? -72.446 57.906  17.337 1.00 92.34  ? 383 ALA B O   1 
ATOM   6518  C CB  . ALA B 1 375 ? -74.044 58.562  19.833 1.00 80.14  ? 383 ALA B CB  1 
ATOM   6519  N N   . CYS B 1 376 ? -71.834 60.034  17.713 1.00 88.11  ? 384 CYS B N   1 
ATOM   6520  C CA  . CYS B 1 376 ? -70.437 59.950  17.333 1.00 91.30  ? 384 CYS B CA  1 
ATOM   6521  C C   . CYS B 1 376 ? -69.743 61.185  17.907 1.00 98.05  ? 384 CYS B C   1 
ATOM   6522  O O   . CYS B 1 376 ? -70.401 62.073  18.432 1.00 148.19 ? 384 CYS B O   1 
ATOM   6523  C CB  . CYS B 1 376 ? -70.297 59.879  15.824 1.00 85.12  ? 384 CYS B CB  1 
ATOM   6524  S SG  . CYS B 1 376 ? -70.711 61.429  14.987 1.00 135.12 ? 384 CYS B SG  1 
ATOM   6525  N N   . ASN B 1 377 ? -68.428 61.297  17.740 1.00 95.27  ? 385 ASN B N   1 
ATOM   6526  C CA  . ASN B 1 377 ? -67.695 62.403  18.332 1.00 87.34  ? 385 ASN B CA  1 
ATOM   6527  C C   . ASN B 1 377 ? -66.739 62.955  17.283 1.00 95.35  ? 385 ASN B C   1 
ATOM   6528  O O   . ASN B 1 377 ? -66.303 62.209  16.382 1.00 81.90  ? 385 ASN B O   1 
ATOM   6529  C CB  . ASN B 1 377 ? -66.979 61.996  19.620 1.00 82.13  ? 385 ASN B CB  1 
ATOM   6530  C CG  . ASN B 1 377 ? -65.897 60.969  19.384 1.00 97.16  ? 385 ASN B CG  1 
ATOM   6531  O OD1 . ASN B 1 377 ? -66.172 59.765  19.386 1.00 108.08 ? 385 ASN B OD1 1 
ATOM   6532  N ND2 . ASN B 1 377 ? -64.682 61.439  19.132 1.00 97.69  ? 385 ASN B ND2 1 
ATOM   6533  N N   . LYS B 1 378 ? -66.411 64.250  17.453 1.00 88.08  ? 386 LYS B N   1 
ATOM   6534  C CA  . LYS B 1 378 ? -65.593 64.985  16.485 1.00 88.93  ? 386 LYS B CA  1 
ATOM   6535  C C   . LYS B 1 378 ? -64.170 64.407  16.506 1.00 79.94  ? 386 LYS B C   1 
ATOM   6536  O O   . LYS B 1 378 ? -63.948 63.387  17.158 1.00 65.83  ? 386 LYS B O   1 
ATOM   6537  C CB  . LYS B 1 378 ? -65.718 66.500  16.722 1.00 58.63  ? 386 LYS B CB  1 
ATOM   6538  C CG  . LYS B 1 378 ? -65.369 66.829  18.160 1.00 76.36  ? 386 LYS B CG  1 
ATOM   6539  C CD  . LYS B 1 378 ? -64.774 68.165  18.583 1.00 80.27  ? 386 LYS B CD  1 
ATOM   6540  C CE  . LYS B 1 378 ? -64.650 68.201  20.073 1.00 106.46 ? 386 LYS B CE  1 
ATOM   6541  N NZ  . LYS B 1 378 ? -65.995 68.156  20.671 1.00 134.53 ? 386 LYS B NZ  1 
ATOM   6542  N N   . ASN B 1 379 ? -63.208 65.054  15.819 1.00 67.72  ? 387 ASN B N   1 
ATOM   6543  C CA  . ASN B 1 379 ? -61.822 64.592  15.855 1.00 76.93  ? 387 ASN B CA  1 
ATOM   6544  C C   . ASN B 1 379 ? -60.986 65.260  14.739 1.00 71.16  ? 387 ASN B C   1 
ATOM   6545  O O   . ASN B 1 379 ? -61.383 65.245  13.577 1.00 74.49  ? 387 ASN B O   1 
ATOM   6546  C CB  . ASN B 1 379 ? -61.870 63.067  15.791 1.00 65.75  ? 387 ASN B CB  1 
ATOM   6547  C CG  . ASN B 1 379 ? -60.565 62.367  16.039 1.00 77.54  ? 387 ASN B CG  1 
ATOM   6548  O OD1 . ASN B 1 379 ? -59.558 62.720  15.417 1.00 73.64  ? 387 ASN B OD1 1 
ATOM   6549  N ND2 . ASN B 1 379 ? -60.587 61.345  16.882 1.00 95.81  ? 387 ASN B ND2 1 
ATOM   6550  N N   . THR B 1 380 ? -59.806 65.803  15.057 1.00 58.03  ? 388 THR B N   1 
ATOM   6551  C CA  . THR B 1 380 ? -58.964 66.430  14.042 1.00 62.49  ? 388 THR B CA  1 
ATOM   6552  C C   . THR B 1 380 ? -58.457 65.372  13.058 1.00 62.70  ? 388 THR B C   1 
ATOM   6553  O O   . THR B 1 380 ? -58.183 64.248  13.450 1.00 59.02  ? 388 THR B O   1 
ATOM   6554  C CB  . THR B 1 380 ? -57.826 67.263  14.648 1.00 62.92  ? 388 THR B CB  1 
ATOM   6555  O OG1 . THR B 1 380 ? -56.950 66.451  15.441 1.00 40.49  ? 388 THR B OG1 1 
ATOM   6556  C CG2 . THR B 1 380 ? -58.386 68.452  15.421 1.00 90.21  ? 388 THR B CG2 1 
ATOM   6557  N N   . CYS B 1 381 ? -58.290 65.750  11.781 1.00 53.89  ? 389 CYS B N   1 
ATOM   6558  C CA  . CYS B 1 381 ? -57.654 64.877  10.802 1.00 87.94  ? 389 CYS B CA  1 
ATOM   6559  C C   . CYS B 1 381 ? -56.216 65.338  10.640 1.00 89.72  ? 389 CYS B C   1 
ATOM   6560  O O   . CYS B 1 381 ? -55.915 66.440  11.064 1.00 94.70  ? 389 CYS B O   1 
ATOM   6561  C CB  . CYS B 1 381 ? -58.365 64.989  9.457  1.00 102.00 ? 389 CYS B CB  1 
ATOM   6562  S SG  . CYS B 1 381 ? -60.134 64.673  9.613  1.00 96.74  ? 389 CYS B SG  1 
ATOM   6563  N N   . PRO B 1 382 ? -55.298 64.561  10.032 1.00 89.91  ? 390 PRO B N   1 
ATOM   6564  C CA  . PRO B 1 382 ? -53.916 65.004  9.872  1.00 128.04 ? 390 PRO B CA  1 
ATOM   6565  C C   . PRO B 1 382 ? -53.820 66.460  9.406  1.00 138.95 ? 390 PRO B C   1 
ATOM   6566  O O   . PRO B 1 382 ? -54.487 66.848  8.427  1.00 93.97  ? 390 PRO B O   1 
ATOM   6567  C CB  . PRO B 1 382 ? -53.413 63.982  8.826  1.00 138.53 ? 390 PRO B CB  1 
ATOM   6568  C CG  . PRO B 1 382 ? -54.110 62.727  9.249  1.00 116.16 ? 390 PRO B CG  1 
ATOM   6569  C CD  . PRO B 1 382 ? -55.527 63.244  9.436  1.00 86.32  ? 390 PRO B CD  1 
ATOM   6570  N N   . GLY B 1 383 ? -53.019 67.234  10.166 1.00 113.52 ? 391 GLY B N   1 
ATOM   6571  C CA  . GLY B 1 383 ? -52.705 68.618  9.850  1.00 105.41 ? 391 GLY B CA  1 
ATOM   6572  C C   . GLY B 1 383 ? -53.700 69.560  10.516 1.00 106.01 ? 391 GLY B C   1 
ATOM   6573  O O   . GLY B 1 383 ? -53.308 70.571  11.084 1.00 84.77  ? 391 GLY B O   1 
ATOM   6574  N N   . ASP B 1 384 ? -54.977 69.169  10.505 1.00 132.24 ? 392 ASP B N   1 
ATOM   6575  C CA  . ASP B 1 384 ? -56.193 69.895  10.845 1.00 148.10 ? 392 ASP B CA  1 
ATOM   6576  C C   . ASP B 1 384 ? -55.984 71.394  11.011 1.00 167.66 ? 392 ASP B C   1 
ATOM   6577  O O   . ASP B 1 384 ? -55.129 71.834  11.758 1.00 198.20 ? 392 ASP B O   1 
ATOM   6578  C CB  . ASP B 1 384 ? -57.021 69.293  11.988 1.00 131.71 ? 392 ASP B CB  1 
ATOM   6579  C CG  . ASP B 1 384 ? -58.364 68.724  11.574 1.00 150.29 ? 392 ASP B CG  1 
ATOM   6580  O OD1 . ASP B 1 384 ? -58.445 68.129  10.479 1.00 161.30 ? 392 ASP B OD1 1 
ATOM   6581  O OD2 . ASP B 1 384 ? -59.305 68.942  12.339 1.00 146.08 ? 392 ASP B OD2 1 
ATOM   6582  N N   . ARG B 1 385 ? -56.872 72.130  10.359 1.00 129.24 ? 393 ARG B N   1 
ATOM   6583  C CA  . ARG B 1 385 ? -57.113 73.536  10.598 1.00 100.08 ? 393 ARG B CA  1 
ATOM   6584  C C   . ARG B 1 385 ? -56.799 73.901  12.058 1.00 133.15 ? 393 ARG B C   1 
ATOM   6585  O O   . ARG B 1 385 ? -55.706 74.394  12.361 1.00 156.68 ? 393 ARG B O   1 
ATOM   6586  C CB  . ARG B 1 385 ? -58.464 73.768  9.907  1.00 64.86  ? 393 ARG B CB  1 
ATOM   6587  C CG  . ARG B 1 385 ? -58.045 73.761  8.445  1.00 73.62  ? 393 ARG B CG  1 
ATOM   6588  C CD  . ARG B 1 385 ? -56.738 74.538  8.352  1.00 111.86 ? 393 ARG B CD  1 
ATOM   6589  N NE  . ARG B 1 385 ? -56.061 74.497  7.044  1.00 140.60 ? 393 ARG B NE  1 
ATOM   6590  C CZ  . ARG B 1 385 ? -55.211 75.406  6.546  1.00 139.56 ? 393 ARG B CZ  1 
ATOM   6591  N NH1 . ARG B 1 385 ? -55.187 76.657  6.999  1.00 138.17 ? 393 ARG B NH1 1 
ATOM   6592  N NH2 . ARG B 1 385 ? -54.415 75.063  5.546  1.00 132.79 ? 393 ARG B NH2 1 
ATOM   6593  N N   . SER B 1 386 ? -57.721 73.611  12.983 1.00 112.25 ? 394 SER B N   1 
ATOM   6594  C CA  . SER B 1 386 ? -57.611 74.025  14.380 1.00 99.15  ? 394 SER B CA  1 
ATOM   6595  C C   . SER B 1 386 ? -57.989 72.846  15.255 1.00 88.84  ? 394 SER B C   1 
ATOM   6596  O O   . SER B 1 386 ? -58.873 72.094  14.878 1.00 139.36 ? 394 SER B O   1 
ATOM   6597  C CB  . SER B 1 386 ? -58.537 75.192  14.666 1.00 103.33 ? 394 SER B CB  1 
ATOM   6598  O OG  . SER B 1 386 ? -58.880 75.273  16.047 1.00 109.03 ? 394 SER B OG  1 
ATOM   6599  N N   . ALA B 1 387 ? -57.457 72.758  16.478 1.00 80.28  ? 395 ALA B N   1 
ATOM   6600  C CA  . ALA B 1 387 ? -57.990 71.797  17.449 1.00 100.29 ? 395 ALA B CA  1 
ATOM   6601  C C   . ALA B 1 387 ? -59.346 72.294  17.954 1.00 102.30 ? 395 ALA B C   1 
ATOM   6602  O O   . ALA B 1 387 ? -60.119 71.525  18.545 1.00 75.59  ? 395 ALA B O   1 
ATOM   6603  C CB  . ALA B 1 387 ? -57.008 71.459  18.580 1.00 86.51  ? 395 ALA B CB  1 
ATOM   6604  N N   . LEU B 1 388 ? -59.616 73.585  17.689 1.00 123.46 ? 396 LEU B N   1 
ATOM   6605  C CA  . LEU B 1 388 ? -60.829 74.259  18.152 1.00 112.04 ? 396 LEU B CA  1 
ATOM   6606  C C   . LEU B 1 388 ? -61.999 73.801  17.285 1.00 108.16 ? 396 LEU B C   1 
ATOM   6607  O O   . LEU B 1 388 ? -63.038 73.450  17.857 1.00 70.28  ? 396 LEU B O   1 
ATOM   6608  C CB  . LEU B 1 388 ? -60.767 75.793  18.171 1.00 88.22  ? 396 LEU B CB  1 
ATOM   6609  C CG  . LEU B 1 388 ? -59.698 76.514  19.025 1.00 87.28  ? 396 LEU B CG  1 
ATOM   6610  C CD1 . LEU B 1 388 ? -59.373 77.861  18.271 1.00 61.06  ? 396 LEU B CD1 1 
ATOM   6611  C CD2 . LEU B 1 388 ? -59.922 76.699  20.611 1.00 58.99  ? 396 LEU B CD2 1 
ATOM   6612  N N   . ARG B 1 389 ? -61.723 73.706  15.964 1.00 110.43 ? 397 ARG B N   1 
ATOM   6613  C CA  . ARG B 1 389 ? -62.643 73.404  14.864 1.00 106.53 ? 397 ARG B CA  1 
ATOM   6614  C C   . ARG B 1 389 ? -62.168 72.146  14.111 1.00 132.71 ? 397 ARG B C   1 
ATOM   6615  O O   . ARG B 1 389 ? -61.646 72.205  12.970 1.00 137.49 ? 397 ARG B O   1 
ATOM   6616  C CB  . ARG B 1 389 ? -62.731 74.608  13.911 1.00 74.20  ? 397 ARG B CB  1 
ATOM   6617  C CG  . ARG B 1 389 ? -63.646 74.356  12.721 1.00 86.12  ? 397 ARG B CG  1 
ATOM   6618  C CD  . ARG B 1 389 ? -62.913 74.550  11.405 1.00 87.94  ? 397 ARG B CD  1 
ATOM   6619  N NE  . ARG B 1 389 ? -62.809 75.852  10.730 1.00 75.57  ? 397 ARG B NE  1 
ATOM   6620  C CZ  . ARG B 1 389 ? -62.885 75.913  9.380  1.00 113.89 ? 397 ARG B CZ  1 
ATOM   6621  N NH1 . ARG B 1 389 ? -63.503 74.961  8.662  1.00 97.31  ? 397 ARG B NH1 1 
ATOM   6622  N NH2 . ARG B 1 389 ? -62.392 76.970  8.736  1.00 138.61 ? 397 ARG B NH2 1 
ATOM   6623  N N   . PRO B 1 390 ? -62.372 70.946  14.713 1.00 109.66 ? 398 PRO B N   1 
ATOM   6624  C CA  . PRO B 1 390 ? -61.906 69.676  14.147 1.00 111.43 ? 398 PRO B CA  1 
ATOM   6625  C C   . PRO B 1 390 ? -62.640 69.333  12.851 1.00 118.38 ? 398 PRO B C   1 
ATOM   6626  O O   . PRO B 1 390 ? -63.853 69.442  12.743 1.00 97.20  ? 398 PRO B O   1 
ATOM   6627  C CB  . PRO B 1 390 ? -62.205 68.673  15.257 1.00 95.34  ? 398 PRO B CB  1 
ATOM   6628  C CG  . PRO B 1 390 ? -63.413 69.280  15.962 1.00 110.87 ? 398 PRO B CG  1 
ATOM   6629  C CD  . PRO B 1 390 ? -63.061 70.748  15.995 1.00 106.58 ? 398 PRO B CD  1 
ATOM   6630  N N   . SER B 1 391 ? -61.884 68.934  11.839 1.00 111.58 ? 399 SER B N   1 
ATOM   6631  C CA  . SER B 1 391 ? -62.419 68.681  10.512 1.00 121.30 ? 399 SER B CA  1 
ATOM   6632  C C   . SER B 1 391 ? -62.980 67.272  10.370 1.00 113.81 ? 399 SER B C   1 
ATOM   6633  O O   . SER B 1 391 ? -63.403 66.909  9.270  1.00 143.24 ? 399 SER B O   1 
ATOM   6634  C CB  . SER B 1 391 ? -61.356 68.863  9.477  1.00 110.57 ? 399 SER B CB  1 
ATOM   6635  O OG  . SER B 1 391 ? -60.675 70.103  9.619  1.00 150.85 ? 399 SER B OG  1 
ATOM   6636  N N   . GLY B 1 392 ? -62.884 66.449  11.418 1.00 65.93  ? 400 GLY B N   1 
ATOM   6637  C CA  . GLY B 1 392 ? -63.161 65.024  11.329 1.00 77.55  ? 400 GLY B CA  1 
ATOM   6638  C C   . GLY B 1 392 ? -64.268 64.540  12.270 1.00 94.48  ? 400 GLY B C   1 
ATOM   6639  O O   . GLY B 1 392 ? -64.609 65.183  13.253 1.00 107.31 ? 400 GLY B O   1 
ATOM   6640  N N   . LEU B 1 393 ? -64.836 63.378  11.940 1.00 97.39  ? 401 LEU B N   1 
ATOM   6641  C CA  . LEU B 1 393 ? -65.779 62.657  12.769 1.00 87.69  ? 401 LEU B CA  1 
ATOM   6642  C C   . LEU B 1 393 ? -65.238 61.251  12.905 1.00 104.88 ? 401 LEU B C   1 
ATOM   6643  O O   . LEU B 1 393 ? -64.857 60.631  11.882 1.00 103.14 ? 401 LEU B O   1 
ATOM   6644  C CB  . LEU B 1 393 ? -67.088 62.579  11.977 1.00 80.73  ? 401 LEU B CB  1 
ATOM   6645  C CG  . LEU B 1 393 ? -68.040 63.753  12.155 1.00 80.40  ? 401 LEU B CG  1 
ATOM   6646  C CD1 . LEU B 1 393 ? -69.309 63.278  11.489 1.00 67.41  ? 401 LEU B CD1 1 
ATOM   6647  C CD2 . LEU B 1 393 ? -68.252 63.913  13.663 1.00 107.95 ? 401 LEU B CD2 1 
ATOM   6648  N N   . ARG B 1 394 ? -65.185 60.764  14.153 1.00 82.75  ? 402 ARG B N   1 
ATOM   6649  C CA  . ARG B 1 394 ? -64.727 59.396  14.313 1.00 89.23  ? 402 ARG B CA  1 
ATOM   6650  C C   . ARG B 1 394 ? -65.945 58.484  14.356 1.00 112.08 ? 402 ARG B C   1 
ATOM   6651  O O   . ARG B 1 394 ? -66.822 58.710  15.180 1.00 134.69 ? 402 ARG B O   1 
ATOM   6652  C CB  . ARG B 1 394 ? -63.843 59.282  15.547 1.00 83.13  ? 402 ARG B CB  1 
ATOM   6653  C CG  . ARG B 1 394 ? -63.248 57.891  15.711 1.00 89.58  ? 402 ARG B CG  1 
ATOM   6654  C CD  . ARG B 1 394 ? -62.519 57.690  17.051 1.00 70.27  ? 402 ARG B CD  1 
ATOM   6655  N NE  . ARG B 1 394 ? -63.459 57.825  18.163 1.00 86.65  ? 402 ARG B NE  1 
ATOM   6656  C CZ  . ARG B 1 394 ? -63.132 57.764  19.418 1.00 81.10  ? 402 ARG B CZ  1 
ATOM   6657  N NH1 . ARG B 1 394 ? -61.893 57.502  19.740 1.00 68.43  ? 402 ARG B NH1 1 
ATOM   6658  N NH2 . ARG B 1 394 ? -64.055 57.927  20.352 1.00 111.70 ? 402 ARG B NH2 1 
ATOM   6659  N N   . LEU B 1 395 ? -65.972 57.452  13.493 1.00 106.38 ? 403 LEU B N   1 
ATOM   6660  C CA  . LEU B 1 395 ? -67.089 56.511  13.459 1.00 108.88 ? 403 LEU B CA  1 
ATOM   6661  C C   . LEU B 1 395 ? -66.615 55.086  13.724 1.00 121.63 ? 403 LEU B C   1 
ATOM   6662  O O   . LEU B 1 395 ? -65.594 54.677  13.155 1.00 101.05 ? 403 LEU B O   1 
ATOM   6663  C CB  . LEU B 1 395 ? -67.813 56.568  12.120 1.00 104.97 ? 403 LEU B CB  1 
ATOM   6664  C CG  . LEU B 1 395 ? -68.384 57.924  11.736 1.00 101.08 ? 403 LEU B CG  1 
ATOM   6665  C CD1 . LEU B 1 395 ? -68.949 57.804  10.317 1.00 78.96  ? 403 LEU B CD1 1 
ATOM   6666  C CD2 . LEU B 1 395 ? -69.436 58.268  12.773 1.00 85.23  ? 403 LEU B CD2 1 
ATOM   6667  N N   . GLY B 1 396 ? -67.336 54.358  14.585 1.00 99.29  ? 404 GLY B N   1 
ATOM   6668  C CA  . GLY B 1 396 ? -66.964 52.978  14.845 1.00 78.81  ? 404 GLY B CA  1 
ATOM   6669  C C   . GLY B 1 396 ? -68.194 52.075  14.857 1.00 95.99  ? 404 GLY B C   1 
ATOM   6670  O O   . GLY B 1 396 ? -69.316 52.505  15.166 1.00 75.63  ? 404 GLY B O   1 
ATOM   6671  N N   . THR B 1 397 ? -67.938 50.781  14.618 1.00 87.99  ? 405 THR B N   1 
ATOM   6672  C CA  . THR B 1 397 ? -69.016 49.817  14.439 1.00 82.86  ? 405 THR B CA  1 
ATOM   6673  C C   . THR B 1 397 ? -69.297 48.910  15.634 1.00 102.26 ? 405 THR B C   1 
ATOM   6674  O O   . THR B 1 397 ? -70.359 48.292  15.621 1.00 83.24  ? 405 THR B O   1 
ATOM   6675  C CB  . THR B 1 397 ? -68.741 49.031  13.160 1.00 57.57  ? 405 THR B CB  1 
ATOM   6676  O OG1 . THR B 1 397 ? -67.547 48.301  13.383 1.00 63.69  ? 405 THR B OG1 1 
ATOM   6677  C CG2 . THR B 1 397 ? -68.551 49.984  11.988 1.00 41.79  ? 405 THR B CG2 1 
ATOM   6678  N N   . PRO B 1 398 ? -68.396 48.761  16.648 1.00 109.05 ? 406 PRO B N   1 
ATOM   6679  C CA  . PRO B 1 398 ? -68.562 47.748  17.688 1.00 91.21  ? 406 PRO B CA  1 
ATOM   6680  C C   . PRO B 1 398 ? -69.935 47.793  18.338 1.00 101.78 ? 406 PRO B C   1 
ATOM   6681  O O   . PRO B 1 398 ? -70.621 46.769  18.397 1.00 91.03  ? 406 PRO B O   1 
ATOM   6682  C CB  . PRO B 1 398 ? -67.490 48.120  18.659 1.00 85.27  ? 406 PRO B CB  1 
ATOM   6683  C CG  . PRO B 1 398 ? -66.401 48.602  17.789 1.00 99.77  ? 406 PRO B CG  1 
ATOM   6684  C CD  . PRO B 1 398 ? -67.133 49.498  16.830 1.00 104.48 ? 406 PRO B CD  1 
ATOM   6685  N N   . ALA B 1 399 ? -70.348 48.995  18.761 1.00 102.70 ? 407 ALA B N   1 
ATOM   6686  C CA  . ALA B 1 399 ? -71.574 49.081  19.541 1.00 96.66  ? 407 ALA B CA  1 
ATOM   6687  C C   . ALA B 1 399 ? -72.763 48.491  18.781 1.00 102.14 ? 407 ALA B C   1 
ATOM   6688  O O   . ALA B 1 399 ? -73.429 47.569  19.262 1.00 67.02  ? 407 ALA B O   1 
ATOM   6689  C CB  . ALA B 1 399 ? -71.806 50.519  19.951 1.00 71.75  ? 407 ALA B CB  1 
ATOM   6690  N N   . LEU B 1 400 ? -73.019 49.042  17.580 1.00 130.27 ? 408 LEU B N   1 
ATOM   6691  C CA  . LEU B 1 400 ? -74.165 48.646  16.766 1.00 101.93 ? 408 LEU B CA  1 
ATOM   6692  C C   . LEU B 1 400 ? -74.021 47.184  16.360 1.00 100.12 ? 408 LEU B C   1 
ATOM   6693  O O   . LEU B 1 400 ? -75.019 46.486  16.258 1.00 104.27 ? 408 LEU B O   1 
ATOM   6694  C CB  . LEU B 1 400 ? -74.229 49.553  15.539 1.00 93.88  ? 408 LEU B CB  1 
ATOM   6695  C CG  . LEU B 1 400 ? -74.931 50.895  15.750 1.00 108.49 ? 408 LEU B CG  1 
ATOM   6696  C CD1 . LEU B 1 400 ? -74.863 51.755  14.507 1.00 109.11 ? 408 LEU B CD1 1 
ATOM   6697  C CD2 . LEU B 1 400 ? -76.363 50.684  16.205 1.00 88.81  ? 408 LEU B CD2 1 
ATOM   6698  N N   . THR B 1 401 ? -72.783 46.736  16.088 1.00 95.75  ? 409 THR B N   1 
ATOM   6699  C CA  . THR B 1 401 ? -72.571 45.373  15.623 1.00 91.59  ? 409 THR B CA  1 
ATOM   6700  C C   . THR B 1 401 ? -73.001 44.421  16.732 1.00 95.84  ? 409 THR B C   1 
ATOM   6701  O O   . THR B 1 401 ? -73.560 43.362  16.496 1.00 146.10 ? 409 THR B O   1 
ATOM   6702  C CB  . THR B 1 401 ? -71.134 45.125  15.156 1.00 98.63  ? 409 THR B CB  1 
ATOM   6703  O OG1 . THR B 1 401 ? -70.811 46.093  14.149 1.00 123.51 ? 409 THR B OG1 1 
ATOM   6704  C CG2 . THR B 1 401 ? -70.954 43.749  14.528 1.00 94.62  ? 409 THR B CG2 1 
ATOM   6705  N N   . SER B 1 402 ? -72.715 44.785  17.970 1.00 97.87  ? 410 SER B N   1 
ATOM   6706  C CA  . SER B 1 402 ? -73.093 43.948  19.097 1.00 87.10  ? 410 SER B CA  1 
ATOM   6707  C C   . SER B 1 402 ? -74.621 43.900  19.173 1.00 79.11  ? 410 SER B C   1 
ATOM   6708  O O   . SER B 1 402 ? -75.195 43.142  19.937 1.00 85.62  ? 410 SER B O   1 
ATOM   6709  C CB  . SER B 1 402 ? -72.514 44.521  20.378 1.00 103.39 ? 410 SER B CB  1 
ATOM   6710  O OG  . SER B 1 402 ? -71.093 44.431  20.436 1.00 103.92 ? 410 SER B OG  1 
ATOM   6711  N N   . ARG B 1 403 ? -75.293 44.780  18.425 1.00 64.62  ? 411 ARG B N   1 
ATOM   6712  C CA  . ARG B 1 403 ? -76.751 44.782  18.407 1.00 86.02  ? 411 ARG B CA  1 
ATOM   6713  C C   . ARG B 1 403 ? -77.256 43.824  17.309 1.00 102.47 ? 411 ARG B C   1 
ATOM   6714  O O   . ARG B 1 403 ? -78.446 43.440  17.238 1.00 94.26  ? 411 ARG B O   1 
ATOM   6715  C CB  . ARG B 1 403 ? -77.258 46.224  18.238 1.00 73.82  ? 411 ARG B CB  1 
ATOM   6716  C CG  . ARG B 1 403 ? -77.020 47.104  19.440 1.00 66.89  ? 411 ARG B CG  1 
ATOM   6717  C CD  . ARG B 1 403 ? -77.991 48.212  19.077 1.00 74.52  ? 411 ARG B CD  1 
ATOM   6718  N NE  . ARG B 1 403 ? -79.387 48.010  19.479 1.00 76.67  ? 411 ARG B NE  1 
ATOM   6719  C CZ  . ARG B 1 403 ? -80.171 49.037  19.898 1.00 95.39  ? 411 ARG B CZ  1 
ATOM   6720  N NH1 . ARG B 1 403 ? -79.689 50.277  19.977 1.00 106.82 ? 411 ARG B NH1 1 
ATOM   6721  N NH2 . ARG B 1 403 ? -81.437 48.815  20.201 1.00 89.72  ? 411 ARG B NH2 1 
ATOM   6722  N N   . GLY B 1 404 ? -76.361 43.454  16.393 1.00 79.99  ? 412 GLY B N   1 
ATOM   6723  C CA  . GLY B 1 404 ? -76.794 42.513  15.376 1.00 87.04  ? 412 GLY B CA  1 
ATOM   6724  C C   . GLY B 1 404 ? -76.649 43.052  13.950 1.00 101.23 ? 412 GLY B C   1 
ATOM   6725  O O   . GLY B 1 404 ? -76.659 42.268  13.002 1.00 119.62 ? 412 GLY B O   1 
ATOM   6726  N N   . LEU B 1 405 ? -76.468 44.375  13.812 1.00 102.77 ? 413 LEU B N   1 
ATOM   6727  C CA  . LEU B 1 405 ? -76.357 45.015  12.504 1.00 100.65 ? 413 LEU B CA  1 
ATOM   6728  C C   . LEU B 1 405 ? -75.314 44.313  11.619 1.00 96.70  ? 413 LEU B C   1 
ATOM   6729  O O   . LEU B 1 405 ? -74.205 43.979  12.075 1.00 77.47  ? 413 LEU B O   1 
ATOM   6730  C CB  . LEU B 1 405 ? -76.064 46.517  12.624 1.00 85.50  ? 413 LEU B CB  1 
ATOM   6731  C CG  . LEU B 1 405 ? -77.227 47.455  12.973 1.00 82.15  ? 413 LEU B CG  1 
ATOM   6732  C CD1 . LEU B 1 405 ? -77.685 47.392  14.421 1.00 97.87  ? 413 LEU B CD1 1 
ATOM   6733  C CD2 . LEU B 1 405 ? -76.764 48.857  12.690 1.00 85.83  ? 413 LEU B CD2 1 
ATOM   6734  N N   . LEU B 1 406 ? -75.679 44.169  10.325 1.00 69.84  ? 414 LEU B N   1 
ATOM   6735  C CA  . LEU B 1 406 ? -74.776 43.645  9.313  1.00 87.48  ? 414 LEU B CA  1 
ATOM   6736  C C   . LEU B 1 406 ? -74.536 44.694  8.232  1.00 99.00  ? 414 LEU B C   1 
ATOM   6737  O O   . LEU B 1 406 ? -74.988 45.852  8.409  1.00 81.36  ? 414 LEU B O   1 
ATOM   6738  C CB  . LEU B 1 406 ? -75.368 42.385  8.690  1.00 103.17 ? 414 LEU B CB  1 
ATOM   6739  C CG  . LEU B 1 406 ? -75.592 41.141  9.554  1.00 92.82  ? 414 LEU B CG  1 
ATOM   6740  C CD1 . LEU B 1 406 ? -75.384 40.028  8.479  1.00 92.45  ? 414 LEU B CD1 1 
ATOM   6741  C CD2 . LEU B 1 406 ? -74.711 40.777  10.717 1.00 111.95 ? 414 LEU B CD2 1 
ATOM   6742  N N   . GLU B 1 407 ? -73.880 44.274  7.103  1.00 70.32  ? 415 GLU B N   1 
ATOM   6743  C CA  . GLU B 1 407 ? -73.465 45.319  6.164  1.00 85.65  ? 415 GLU B CA  1 
ATOM   6744  C C   . GLU B 1 407 ? -74.657 46.082  5.584  1.00 94.55  ? 415 GLU B C   1 
ATOM   6745  O O   . GLU B 1 407 ? -74.536 47.299  5.481  1.00 76.78  ? 415 GLU B O   1 
ATOM   6746  C CB  . GLU B 1 407 ? -72.298 45.308  5.166  1.00 82.99  ? 415 GLU B CB  1 
ATOM   6747  C CG  . GLU B 1 407 ? -71.057 44.546  5.620  1.00 89.37  ? 415 GLU B CG  1 
ATOM   6748  C CD  . GLU B 1 407 ? -71.246 43.037  5.475  1.00 91.09  ? 415 GLU B CD  1 
ATOM   6749  O OE1 . GLU B 1 407 ? -72.331 42.499  5.973  1.00 65.74  ? 415 GLU B OE1 1 
ATOM   6750  O OE2 . GLU B 1 407 ? -70.282 42.434  4.868  1.00 45.02  ? 415 GLU B OE2 1 
ATOM   6751  N N   . LYS B 1 408 ? -75.781 45.416  5.243  1.00 95.07  ? 416 LYS B N   1 
ATOM   6752  C CA  . LYS B 1 408 ? -76.898 46.157  4.665  1.00 104.67 ? 416 LYS B CA  1 
ATOM   6753  C C   . LYS B 1 408 ? -77.334 47.254  5.637  1.00 122.17 ? 416 LYS B C   1 
ATOM   6754  O O   . LYS B 1 408 ? -77.533 48.408  5.237  1.00 155.71 ? 416 LYS B O   1 
ATOM   6755  C CB  . LYS B 1 408 ? -78.010 45.322  4.022  1.00 103.04 ? 416 LYS B CB  1 
ATOM   6756  C CG  . LYS B 1 408 ? -78.689 44.258  4.890  1.00 122.80 ? 416 LYS B CG  1 
ATOM   6757  C CD  . LYS B 1 408 ? -80.031 43.850  4.264  1.00 124.45 ? 416 LYS B CD  1 
ATOM   6758  C CE  . LYS B 1 408 ? -80.947 42.817  4.904  1.00 91.99  ? 416 LYS B CE  1 
ATOM   6759  N NZ  . LYS B 1 408 ? -81.291 42.949  6.333  1.00 72.61  ? 416 LYS B NZ  1 
ATOM   6760  N N   . ASP B 1 409 ? -77.436 46.885  6.922  1.00 110.54 ? 417 ASP B N   1 
ATOM   6761  C CA  . ASP B 1 409 ? -77.852 47.795  7.983  1.00 113.28 ? 417 ASP B CA  1 
ATOM   6762  C C   . ASP B 1 409 ? -76.905 48.994  8.067  1.00 127.46 ? 417 ASP B C   1 
ATOM   6763  O O   . ASP B 1 409 ? -77.351 50.141  8.172  1.00 124.74 ? 417 ASP B O   1 
ATOM   6764  C CB  . ASP B 1 409 ? -77.887 47.041  9.295  1.00 119.85 ? 417 ASP B CB  1 
ATOM   6765  C CG  . ASP B 1 409 ? -78.751 45.796  9.298  1.00 128.24 ? 417 ASP B CG  1 
ATOM   6766  O OD1 . ASP B 1 409 ? -79.965 45.943  9.205  1.00 153.99 ? 417 ASP B OD1 1 
ATOM   6767  O OD2 . ASP B 1 409 ? -78.160 44.693  9.358  1.00 118.69 ? 417 ASP B OD2 1 
ATOM   6768  N N   . PHE B 1 410 ? -75.593 48.713  8.017  1.00 101.99 ? 418 PHE B N   1 
ATOM   6769  C CA  . PHE B 1 410 ? -74.563 49.740  8.093  1.00 104.67 ? 418 PHE B CA  1 
ATOM   6770  C C   . PHE B 1 410 ? -74.665 50.691  6.903  1.00 100.22 ? 418 PHE B C   1 
ATOM   6771  O O   . PHE B 1 410 ? -74.127 51.798  6.948  1.00 110.67 ? 418 PHE B O   1 
ATOM   6772  C CB  . PHE B 1 410 ? -73.123 49.230  8.270  1.00 86.88  ? 418 PHE B CB  1 
ATOM   6773  C CG  . PHE B 1 410 ? -72.773 49.305  9.747  1.00 90.56  ? 418 PHE B CG  1 
ATOM   6774  C CD1 . PHE B 1 410 ? -72.369 50.508  10.312 1.00 93.31  ? 418 PHE B CD1 1 
ATOM   6775  C CD2 . PHE B 1 410 ? -72.977 48.216  10.599 1.00 91.73  ? 418 PHE B CD2 1 
ATOM   6776  C CE1 . PHE B 1 410 ? -72.171 50.616  11.680 1.00 80.78  ? 418 PHE B CE1 1 
ATOM   6777  C CE2 . PHE B 1 410 ? -72.736 48.297  11.971 1.00 74.03  ? 418 PHE B CE2 1 
ATOM   6778  C CZ  . PHE B 1 410 ? -72.336 49.504  12.506 1.00 94.27  ? 418 PHE B CZ  1 
ATOM   6779  N N   . GLN B 1 411 ? -75.296 50.226  5.821  1.00 77.08  ? 419 GLN B N   1 
ATOM   6780  C CA  . GLN B 1 411 ? -75.397 51.063  4.635  1.00 97.44  ? 419 GLN B CA  1 
ATOM   6781  C C   . GLN B 1 411 ? -76.461 52.114  4.926  1.00 106.37 ? 419 GLN B C   1 
ATOM   6782  O O   . GLN B 1 411 ? -76.301 53.282  4.555  1.00 112.99 ? 419 GLN B O   1 
ATOM   6783  C CB  . GLN B 1 411 ? -75.608 50.255  3.348  1.00 75.48  ? 419 GLN B CB  1 
ATOM   6784  C CG  . GLN B 1 411 ? -74.622 49.110  3.284  1.00 81.66  ? 419 GLN B CG  1 
ATOM   6785  C CD  . GLN B 1 411 ? -74.378 48.592  1.907  1.00 76.29  ? 419 GLN B CD  1 
ATOM   6786  O OE1 . GLN B 1 411 ? -73.991 49.353  1.011  1.00 53.65  ? 419 GLN B OE1 1 
ATOM   6787  N NE2 . GLN B 1 411 ? -74.516 47.274  1.818  1.00 75.20  ? 419 GLN B NE2 1 
ATOM   6788  N N   . LYS B 1 412 ? -77.515 51.654  5.626  1.00 83.44  ? 420 LYS B N   1 
ATOM   6789  C CA  . LYS B 1 412 ? -78.649 52.501  5.925  1.00 82.83  ? 420 LYS B CA  1 
ATOM   6790  C C   . LYS B 1 412 ? -78.105 53.569  6.862  1.00 112.97 ? 420 LYS B C   1 
ATOM   6791  O O   . LYS B 1 412 ? -78.544 54.723  6.827  1.00 116.72 ? 420 LYS B O   1 
ATOM   6792  C CB  . LYS B 1 412 ? -79.814 51.670  6.482  1.00 81.33  ? 420 LYS B CB  1 
ATOM   6793  C CG  . LYS B 1 412 ? -81.043 52.490  6.916  1.00 78.41  ? 420 LYS B CG  1 
ATOM   6794  C CD  . LYS B 1 412 ? -82.322 51.691  7.144  1.00 106.62 ? 420 LYS B CD  1 
ATOM   6795  C CE  . LYS B 1 412 ? -83.562 52.566  7.120  1.00 124.45 ? 420 LYS B CE  1 
ATOM   6796  N NZ  . LYS B 1 412 ? -84.711 52.168  7.967  1.00 112.41 ? 420 LYS B NZ  1 
ATOM   6797  N N   . VAL B 1 413 ? -77.142 53.152  7.698  1.00 134.95 ? 421 VAL B N   1 
ATOM   6798  C CA  . VAL B 1 413 ? -76.577 54.032  8.703  1.00 139.53 ? 421 VAL B CA  1 
ATOM   6799  C C   . VAL B 1 413 ? -75.836 55.156  7.997  1.00 116.47 ? 421 VAL B C   1 
ATOM   6800  O O   . VAL B 1 413 ? -76.054 56.335  8.318  1.00 88.47  ? 421 VAL B O   1 
ATOM   6801  C CB  . VAL B 1 413 ? -75.656 53.295  9.691  1.00 121.38 ? 421 VAL B CB  1 
ATOM   6802  C CG1 . VAL B 1 413 ? -74.966 54.278  10.626 1.00 95.13  ? 421 VAL B CG1 1 
ATOM   6803  C CG2 . VAL B 1 413 ? -76.394 52.222  10.481 1.00 119.75 ? 421 VAL B CG2 1 
ATOM   6804  N N   . ALA B 1 414 ? -75.003 54.755  7.021  1.00 108.45 ? 422 ALA B N   1 
ATOM   6805  C CA  . ALA B 1 414 ? -74.203 55.696  6.255  1.00 111.66 ? 422 ALA B CA  1 
ATOM   6806  C C   . ALA B 1 414 ? -75.099 56.776  5.665  1.00 110.01 ? 422 ALA B C   1 
ATOM   6807  O O   . ALA B 1 414 ? -74.750 57.955  5.646  1.00 122.20 ? 422 ALA B O   1 
ATOM   6808  C CB  . ALA B 1 414 ? -73.433 54.966  5.181  1.00 108.42 ? 422 ALA B CB  1 
ATOM   6809  N N   . HIS B 1 415 ? -76.301 56.359  5.271  1.00 105.16 ? 423 HIS B N   1 
ATOM   6810  C CA  . HIS B 1 415 ? -77.236 57.264  4.625  1.00 108.33 ? 423 HIS B CA  1 
ATOM   6811  C C   . HIS B 1 415 ? -77.821 58.214  5.678  1.00 113.61 ? 423 HIS B C   1 
ATOM   6812  O O   . HIS B 1 415 ? -78.060 59.395  5.389  1.00 106.52 ? 423 HIS B O   1 
ATOM   6813  C CB  . HIS B 1 415 ? -78.288 56.451  3.846  1.00 95.42  ? 423 HIS B CB  1 
ATOM   6814  C CG  . HIS B 1 415 ? -77.777 55.477  2.805  1.00 96.92  ? 423 HIS B CG  1 
ATOM   6815  N ND1 . HIS B 1 415 ? -76.832 55.755  1.823  1.00 109.03 ? 423 HIS B ND1 1 
ATOM   6816  C CD2 . HIS B 1 415 ? -78.143 54.197  2.604  1.00 72.79  ? 423 HIS B CD2 1 
ATOM   6817  C CE1 . HIS B 1 415 ? -76.601 54.664  1.090  1.00 65.63  ? 423 HIS B CE1 1 
ATOM   6818  N NE2 . HIS B 1 415 ? -77.375 53.707  1.569  1.00 62.98  ? 423 HIS B NE2 1 
ATOM   6819  N N   . PHE B 1 416 ? -78.100 57.689  6.883  1.00 94.53  ? 424 PHE B N   1 
ATOM   6820  C CA  . PHE B 1 416 ? -78.654 58.534  7.929  1.00 90.81  ? 424 PHE B CA  1 
ATOM   6821  C C   . PHE B 1 416 ? -77.591 59.549  8.351  1.00 102.99 ? 424 PHE B C   1 
ATOM   6822  O O   . PHE B 1 416 ? -77.881 60.731  8.504  1.00 117.21 ? 424 PHE B O   1 
ATOM   6823  C CB  . PHE B 1 416 ? -79.133 57.693  9.098  1.00 83.50  ? 424 PHE B CB  1 
ATOM   6824  C CG  . PHE B 1 416 ? -80.446 56.957  8.919  1.00 83.24  ? 424 PHE B CG  1 
ATOM   6825  C CD1 . PHE B 1 416 ? -80.975 56.688  7.659  1.00 78.91  ? 424 PHE B CD1 1 
ATOM   6826  C CD2 . PHE B 1 416 ? -81.132 56.514  10.062 1.00 78.31  ? 424 PHE B CD2 1 
ATOM   6827  C CE1 . PHE B 1 416 ? -82.144 55.958  7.566  1.00 99.34  ? 424 PHE B CE1 1 
ATOM   6828  C CE2 . PHE B 1 416 ? -82.294 55.775  9.982  1.00 64.26  ? 424 PHE B CE2 1 
ATOM   6829  C CZ  . PHE B 1 416 ? -82.808 55.534  8.726  1.00 109.71 ? 424 PHE B CZ  1 
ATOM   6830  N N   . ILE B 1 417 ? -76.342 59.094  8.473  1.00 90.29  ? 425 ILE B N   1 
ATOM   6831  C CA  . ILE B 1 417 ? -75.232 59.987  8.774  1.00 100.03 ? 425 ILE B CA  1 
ATOM   6832  C C   . ILE B 1 417 ? -75.173 61.092  7.716  1.00 98.70  ? 425 ILE B C   1 
ATOM   6833  O O   . ILE B 1 417 ? -75.037 62.277  8.037  1.00 86.36  ? 425 ILE B O   1 
ATOM   6834  C CB  . ILE B 1 417 ? -73.914 59.197  8.868  1.00 90.83  ? 425 ILE B CB  1 
ATOM   6835  C CG1 . ILE B 1 417 ? -73.894 58.320  10.140 1.00 86.05  ? 425 ILE B CG1 1 
ATOM   6836  C CG2 . ILE B 1 417 ? -72.701 60.124  8.728  1.00 79.06  ? 425 ILE B CG2 1 
ATOM   6837  C CD1 . ILE B 1 417 ? -72.802 57.262  10.146 1.00 106.44 ? 425 ILE B CD1 1 
ATOM   6838  N N   . HIS B 1 418 ? -75.314 60.677  6.449  1.00 80.19  ? 426 HIS B N   1 
ATOM   6839  C CA  . HIS B 1 418 ? -75.197 61.615  5.356  1.00 72.41  ? 426 HIS B CA  1 
ATOM   6840  C C   . HIS B 1 418 ? -76.240 62.725  5.530  1.00 86.70  ? 426 HIS B C   1 
ATOM   6841  O O   . HIS B 1 418 ? -75.913 63.919  5.509  1.00 89.92  ? 426 HIS B O   1 
ATOM   6842  C CB  . HIS B 1 418 ? -75.266 60.907  3.999  1.00 69.17  ? 426 HIS B CB  1 
ATOM   6843  C CG  . HIS B 1 418 ? -75.261 61.966  2.934  1.00 87.07  ? 426 HIS B CG  1 
ATOM   6844  N ND1 . HIS B 1 418 ? -74.164 62.792  2.799  1.00 103.99 ? 426 HIS B ND1 1 
ATOM   6845  C CD2 . HIS B 1 418 ? -76.181 62.434  2.050  1.00 84.72  ? 426 HIS B CD2 1 
ATOM   6846  C CE1 . HIS B 1 418 ? -74.373 63.685  1.826  1.00 113.99 ? 426 HIS B CE1 1 
ATOM   6847  N NE2 . HIS B 1 418 ? -75.602 63.496  1.379  1.00 109.83 ? 426 HIS B NE2 1 
ATOM   6848  N N   . ARG B 1 419 ? -77.506 62.336  5.737  1.00 73.39  ? 427 ARG B N   1 
ATOM   6849  C CA  . ARG B 1 419 ? -78.542 63.323  6.016  1.00 88.46  ? 427 ARG B CA  1 
ATOM   6850  C C   . ARG B 1 419 ? -78.131 64.242  7.177  1.00 98.41  ? 427 ARG B C   1 
ATOM   6851  O O   . ARG B 1 419 ? -78.242 65.466  7.079  1.00 76.25  ? 427 ARG B O   1 
ATOM   6852  C CB  . ARG B 1 419 ? -79.881 62.617  6.298  1.00 74.27  ? 427 ARG B CB  1 
ATOM   6853  C CG  . ARG B 1 419 ? -80.167 61.640  5.160  1.00 92.38  ? 427 ARG B CG  1 
ATOM   6854  C CD  . ARG B 1 419 ? -81.554 61.541  4.532  1.00 83.64  ? 427 ARG B CD  1 
ATOM   6855  N NE  . ARG B 1 419 ? -82.592 60.711  5.137  1.00 76.99  ? 427 ARG B NE  1 
ATOM   6856  C CZ  . ARG B 1 419 ? -83.630 61.187  5.823  1.00 80.16  ? 427 ARG B CZ  1 
ATOM   6857  N NH1 . ARG B 1 419 ? -83.736 62.534  6.006  1.00 64.13  ? 427 ARG B NH1 1 
ATOM   6858  N NH2 . ARG B 1 419 ? -84.511 60.258  6.271  1.00 60.65  ? 427 ARG B NH2 1 
ATOM   6859  N N   . GLY B 1 420 ? -77.656 63.652  8.280  1.00 69.35  ? 428 GLY B N   1 
ATOM   6860  C CA  . GLY B 1 420 ? -77.048 64.451  9.326  1.00 80.98  ? 428 GLY B CA  1 
ATOM   6861  C C   . GLY B 1 420 ? -76.133 65.561  8.780  1.00 84.81  ? 428 GLY B C   1 
ATOM   6862  O O   . GLY B 1 420 ? -76.245 66.721  9.174  1.00 88.82  ? 428 GLY B O   1 
ATOM   6863  N N   . ILE B 1 421 ? -75.199 65.205  7.893  1.00 85.57  ? 429 ILE B N   1 
ATOM   6864  C CA  . ILE B 1 421 ? -74.241 66.156  7.347  1.00 103.80 ? 429 ILE B CA  1 
ATOM   6865  C C   . ILE B 1 421 ? -74.928 67.244  6.515  1.00 108.54 ? 429 ILE B C   1 
ATOM   6866  O O   . ILE B 1 421 ? -74.488 68.404  6.530  1.00 89.52  ? 429 ILE B O   1 
ATOM   6867  C CB  . ILE B 1 421 ? -73.143 65.412  6.568  1.00 90.66  ? 429 ILE B CB  1 
ATOM   6868  C CG1 . ILE B 1 421 ? -72.404 64.419  7.478  1.00 91.93  ? 429 ILE B CG1 1 
ATOM   6869  C CG2 . ILE B 1 421 ? -72.176 66.393  5.879  1.00 71.73  ? 429 ILE B CG2 1 
ATOM   6870  C CD1 . ILE B 1 421 ? -71.850 65.027  8.767  1.00 70.34  ? 429 ILE B CD1 1 
ATOM   6871  N N   . GLU B 1 422 ? -75.967 66.842  5.763  1.00 109.15 ? 430 GLU B N   1 
ATOM   6872  C CA  . GLU B 1 422 ? -76.716 67.770  4.924  1.00 102.63 ? 430 GLU B CA  1 
ATOM   6873  C C   . GLU B 1 422 ? -77.308 68.853  5.826  1.00 109.94 ? 430 GLU B C   1 
ATOM   6874  O O   . GLU B 1 422 ? -77.201 70.048  5.517  1.00 89.20  ? 430 GLU B O   1 
ATOM   6875  C CB  . GLU B 1 422 ? -77.868 67.093  4.150  1.00 68.96  ? 430 GLU B CB  1 
ATOM   6876  C CG  . GLU B 1 422 ? -77.494 66.098  3.064  1.00 83.55  ? 430 GLU B CG  1 
ATOM   6877  C CD  . GLU B 1 422 ? -77.510 66.289  1.512  1.00 94.75  ? 430 GLU B CD  1 
ATOM   6878  O OE1 . GLU B 1 422 ? -78.449 65.679  0.926  1.00 94.01  ? 430 GLU B OE1 1 
ATOM   6879  O OE2 . GLU B 1 422 ? -76.602 66.896  0.838  1.00 65.74  ? 430 GLU B OE2 1 
ATOM   6880  N N   . LEU B 1 423 ? -77.932 68.393  6.934  1.00 77.96  ? 431 LEU B N   1 
ATOM   6881  C CA  . LEU B 1 423 ? -78.563 69.306  7.870  1.00 87.05  ? 431 LEU B CA  1 
ATOM   6882  C C   . LEU B 1 423 ? -77.491 70.230  8.448  1.00 91.79  ? 431 LEU B C   1 
ATOM   6883  O O   . LEU B 1 423 ? -77.634 71.462  8.462  1.00 86.15  ? 431 LEU B O   1 
ATOM   6884  C CB  . LEU B 1 423 ? -79.233 68.498  8.970  1.00 75.94  ? 431 LEU B CB  1 
ATOM   6885  C CG  . LEU B 1 423 ? -80.710 68.201  8.756  1.00 71.56  ? 431 LEU B CG  1 
ATOM   6886  C CD1 . LEU B 1 423 ? -81.242 67.410  9.938  1.00 78.21  ? 431 LEU B CD1 1 
ATOM   6887  C CD2 . LEU B 1 423 ? -81.416 69.538  8.654  1.00 82.52  ? 431 LEU B CD2 1 
ATOM   6888  N N   . THR B 1 424 ? -76.361 69.624  8.820  1.00 67.64  ? 432 THR B N   1 
ATOM   6889  C CA  . THR B 1 424 ? -75.247 70.401  9.325  1.00 103.48 ? 432 THR B CA  1 
ATOM   6890  C C   . THR B 1 424 ? -74.950 71.545  8.355  1.00 135.74 ? 432 THR B C   1 
ATOM   6891  O O   . THR B 1 424 ? -74.876 72.710  8.744  1.00 157.13 ? 432 THR B O   1 
ATOM   6892  C CB  . THR B 1 424 ? -74.062 69.469  9.524  1.00 114.33 ? 432 THR B CB  1 
ATOM   6893  O OG1 . THR B 1 424 ? -74.773 68.653  10.445 1.00 115.97 ? 432 THR B OG1 1 
ATOM   6894  C CG2 . THR B 1 424 ? -72.896 70.149  10.213 1.00 108.66 ? 432 THR B CG2 1 
ATOM   6895  N N   . LEU B 1 425 ? -74.857 71.188  7.071  1.00 110.80 ? 433 LEU B N   1 
ATOM   6896  C CA  . LEU B 1 425 ? -74.498 72.109  6.014  1.00 96.79  ? 433 LEU B CA  1 
ATOM   6897  C C   . LEU B 1 425 ? -75.578 73.175  5.850  1.00 114.70 ? 433 LEU B C   1 
ATOM   6898  O O   . LEU B 1 425 ? -75.261 74.344  5.631  1.00 103.47 ? 433 LEU B O   1 
ATOM   6899  C CB  . LEU B 1 425 ? -74.342 71.180  4.805  1.00 66.68  ? 433 LEU B CB  1 
ATOM   6900  C CG  . LEU B 1 425 ? -72.904 71.060  4.286  1.00 69.52  ? 433 LEU B CG  1 
ATOM   6901  C CD1 . LEU B 1 425 ? -72.484 69.639  3.919  1.00 61.72  ? 433 LEU B CD1 1 
ATOM   6902  C CD2 . LEU B 1 425 ? -72.668 72.064  3.132  1.00 61.48  ? 433 LEU B CD2 1 
ATOM   6903  N N   . GLN B 1 426 ? -76.836 72.735  5.895  1.00 117.82 ? 434 GLN B N   1 
ATOM   6904  C CA  . GLN B 1 426 ? -77.964 73.620  5.676  1.00 132.59 ? 434 GLN B CA  1 
ATOM   6905  C C   . GLN B 1 426 ? -77.898 74.745  6.700  1.00 132.59 ? 434 GLN B C   1 
ATOM   6906  O O   . GLN B 1 426 ? -78.048 75.932  6.382  1.00 179.42 ? 434 GLN B O   1 
ATOM   6907  C CB  . GLN B 1 426 ? -79.283 72.893  5.896  1.00 110.07 ? 434 GLN B CB  1 
ATOM   6908  C CG  . GLN B 1 426 ? -79.578 71.797  4.889  1.00 108.60 ? 434 GLN B CG  1 
ATOM   6909  C CD  . GLN B 1 426 ? -80.908 71.182  5.221  1.00 122.46 ? 434 GLN B CD  1 
ATOM   6910  O OE1 . GLN B 1 426 ? -81.829 71.885  5.644  1.00 98.31  ? 434 GLN B OE1 1 
ATOM   6911  N NE2 . GLN B 1 426 ? -81.020 69.874  5.047  1.00 177.46 ? 434 GLN B NE2 1 
ATOM   6912  N N   . ILE B 1 427 ? -77.755 74.329  7.956  1.00 104.77 ? 435 ILE B N   1 
ATOM   6913  C CA  . ILE B 1 427 ? -77.636 75.303  9.015  1.00 104.17 ? 435 ILE B CA  1 
ATOM   6914  C C   . ILE B 1 427 ? -76.443 76.227  8.748  1.00 111.66 ? 435 ILE B C   1 
ATOM   6915  O O   . ILE B 1 427 ? -76.603 77.448  8.753  1.00 99.12  ? 435 ILE B O   1 
ATOM   6916  C CB  . ILE B 1 427 ? -77.585 74.583  10.358 1.00 86.66  ? 435 ILE B CB  1 
ATOM   6917  C CG1 . ILE B 1 427 ? -78.654 73.494  10.380 1.00 77.20  ? 435 ILE B CG1 1 
ATOM   6918  C CG2 . ILE B 1 427 ? -77.709 75.611  11.490 1.00 100.11 ? 435 ILE B CG2 1 
ATOM   6919  C CD1 . ILE B 1 427 ? -78.667 72.605  11.608 1.00 107.50 ? 435 ILE B CD1 1 
ATOM   6920  N N   . GLN B 1 428 ? -75.266 75.653  8.483  1.00 104.83 ? 436 GLN B N   1 
ATOM   6921  C CA  . GLN B 1 428 ? -74.005 76.376  8.363  1.00 117.71 ? 436 GLN B CA  1 
ATOM   6922  C C   . GLN B 1 428 ? -74.077 77.440  7.263  1.00 138.07 ? 436 GLN B C   1 
ATOM   6923  O O   . GLN B 1 428 ? -73.415 78.467  7.366  1.00 170.19 ? 436 GLN B O   1 
ATOM   6924  C CB  . GLN B 1 428 ? -72.920 75.338  8.052  1.00 103.71 ? 436 GLN B CB  1 
ATOM   6925  C CG  . GLN B 1 428 ? -71.735 75.867  7.230  1.00 80.44  ? 436 GLN B CG  1 
ATOM   6926  C CD  . GLN B 1 428 ? -70.568 74.916  7.286  1.00 85.36  ? 436 GLN B CD  1 
ATOM   6927  O OE1 . GLN B 1 428 ? -70.714 73.693  7.218  1.00 92.06  ? 436 GLN B OE1 1 
ATOM   6928  N NE2 . GLN B 1 428 ? -69.380 75.449  7.482  1.00 81.86  ? 436 GLN B NE2 1 
ATOM   6929  N N   . SER B 1 429 ? -74.793 77.137  6.169  1.00 125.92 ? 437 SER B N   1 
ATOM   6930  C CA  . SER B 1 429 ? -74.777 78.021  5.025  1.00 116.73 ? 437 SER B CA  1 
ATOM   6931  C C   . SER B 1 429 ? -75.787 79.145  5.241  1.00 122.98 ? 437 SER B C   1 
ATOM   6932  O O   . SER B 1 429 ? -75.696 80.140  4.552  1.00 149.47 ? 437 SER B O   1 
ATOM   6933  C CB  . SER B 1 429 ? -74.912 77.301  3.693  1.00 90.03  ? 437 SER B CB  1 
ATOM   6934  O OG  . SER B 1 429 ? -74.893 78.250  2.637  1.00 46.22  ? 437 SER B OG  1 
ATOM   6935  N N   . ASP B 1 430 ? -76.705 79.023  6.216  1.00 117.09 ? 438 ASP B N   1 
ATOM   6936  C CA  . ASP B 1 430 ? -77.425 80.183  6.743  1.00 106.55 ? 438 ASP B CA  1 
ATOM   6937  C C   . ASP B 1 430 ? -76.571 80.860  7.800  1.00 99.61  ? 438 ASP B C   1 
ATOM   6938  O O   . ASP B 1 430 ? -76.620 82.068  8.001  1.00 139.92 ? 438 ASP B O   1 
ATOM   6939  C CB  . ASP B 1 430 ? -78.730 79.786  7.402  1.00 104.90 ? 438 ASP B CB  1 
ATOM   6940  C CG  . ASP B 1 430 ? -79.544 78.843  6.524  1.00 131.93 ? 438 ASP B CG  1 
ATOM   6941  O OD1 . ASP B 1 430 ? -79.152 78.624  5.320  1.00 88.83  ? 438 ASP B OD1 1 
ATOM   6942  O OD2 . ASP B 1 430 ? -80.573 78.342  7.036  1.00 136.62 ? 438 ASP B OD2 1 
ATOM   6943  N N   . THR B 1 431 ? -75.790 80.045  8.494  1.00 115.78 ? 439 THR B N   1 
ATOM   6944  C CA  . THR B 1 431 ? -75.098 80.508  9.678  1.00 95.61  ? 439 THR B CA  1 
ATOM   6945  C C   . THR B 1 431 ? -74.021 81.505  9.291  1.00 101.67 ? 439 THR B C   1 
ATOM   6946  O O   . THR B 1 431 ? -73.772 82.398  10.086 1.00 77.76  ? 439 THR B O   1 
ATOM   6947  C CB  . THR B 1 431 ? -74.656 79.298  10.477 1.00 102.54 ? 439 THR B CB  1 
ATOM   6948  O OG1 . THR B 1 431 ? -75.959 79.327  11.080 1.00 68.34  ? 439 THR B OG1 1 
ATOM   6949  C CG2 . THR B 1 431 ? -73.486 79.594  11.398 1.00 126.08 ? 439 THR B CG2 1 
ATOM   6950  N N   . GLY B 1 432 ? -73.475 81.360  8.070  1.00 112.21 ? 440 GLY B N   1 
ATOM   6951  C CA  . GLY B 1 432 ? -72.569 82.324  7.460  1.00 116.41 ? 440 GLY B CA  1 
ATOM   6952  C C   . GLY B 1 432 ? -71.104 81.964  7.703  1.00 121.95 ? 440 GLY B C   1 
ATOM   6953  O O   . GLY B 1 432 ? -70.795 81.241  8.662  1.00 82.28  ? 440 GLY B O   1 
ATOM   6954  N N   . VAL B 1 433 ? -70.235 82.518  6.828  1.00 128.94 ? 441 VAL B N   1 
ATOM   6955  C CA  . VAL B 1 433 ? -68.788 82.323  6.712  1.00 141.44 ? 441 VAL B CA  1 
ATOM   6956  C C   . VAL B 1 433 ? -68.146 81.940  8.060  1.00 166.21 ? 441 VAL B C   1 
ATOM   6957  O O   . VAL B 1 433 ? -67.862 80.765  8.289  1.00 167.38 ? 441 VAL B O   1 
ATOM   6958  C CB  . VAL B 1 433 ? -68.042 83.482  5.981  1.00 126.52 ? 441 VAL B CB  1 
ATOM   6959  C CG1 . VAL B 1 433 ? -66.531 83.530  6.233  1.00 106.20 ? 441 VAL B CG1 1 
ATOM   6960  C CG2 . VAL B 1 433 ? -68.296 83.561  4.465  1.00 116.16 ? 441 VAL B CG2 1 
ATOM   6961  N N   . ALA B 1 434 ? -67.987 82.914  8.970  1.00 145.80 ? 442 ALA B N   1 
ATOM   6962  C CA  . ALA B 1 434 ? -67.544 82.648  10.337 1.00 147.49 ? 442 ALA B CA  1 
ATOM   6963  C C   . ALA B 1 434 ? -68.725 82.710  11.309 1.00 137.64 ? 442 ALA B C   1 
ATOM   6964  O O   . ALA B 1 434 ? -69.727 83.359  11.008 1.00 133.99 ? 442 ALA B O   1 
ATOM   6965  C CB  . ALA B 1 434 ? -66.460 83.633  10.748 1.00 30.00  ? 442 ALA B CB  1 
ATOM   6966  N N   . ALA B 1 435 ? -68.602 81.999  12.442 1.00 101.79 ? 443 ALA B N   1 
ATOM   6967  C CA  . ALA B 1 435 ? -69.666 81.796  13.427 1.00 105.58 ? 443 ALA B CA  1 
ATOM   6968  C C   . ALA B 1 435 ? -69.152 80.986  14.622 1.00 117.90 ? 443 ALA B C   1 
ATOM   6969  O O   . ALA B 1 435 ? -68.341 80.074  14.455 1.00 156.08 ? 443 ALA B O   1 
ATOM   6970  C CB  . ALA B 1 435 ? -70.915 81.109  12.846 1.00 70.14  ? 443 ALA B CB  1 
ATOM   6971  N N   . THR B 1 436 ? -69.673 81.288  15.823 1.00 105.03 ? 444 THR B N   1 
ATOM   6972  C CA  . THR B 1 436 ? -69.582 80.372  16.960 1.00 123.05 ? 444 THR B CA  1 
ATOM   6973  C C   . THR B 1 436 ? -70.306 79.044  16.681 1.00 108.79 ? 444 THR B C   1 
ATOM   6974  O O   . THR B 1 436 ? -71.301 78.937  15.950 1.00 82.26  ? 444 THR B O   1 
ATOM   6975  C CB  . THR B 1 436 ? -70.001 80.978  18.306 1.00 114.40 ? 444 THR B CB  1 
ATOM   6976  O OG1 . THR B 1 436 ? -71.315 81.473  18.145 1.00 153.21 ? 444 THR B OG1 1 
ATOM   6977  C CG2 . THR B 1 436 ? -69.231 82.201  18.754 1.00 90.30  ? 444 THR B CG2 1 
ATOM   6978  N N   . LEU B 1 437 ? -69.778 77.968  17.275 1.00 125.08 ? 445 LEU B N   1 
ATOM   6979  C CA  . LEU B 1 437 ? -70.547 76.736  17.406 1.00 133.48 ? 445 LEU B CA  1 
ATOM   6980  C C   . LEU B 1 437 ? -71.857 77.064  18.125 1.00 140.55 ? 445 LEU B C   1 
ATOM   6981  O O   . LEU B 1 437 ? -72.818 76.301  17.994 1.00 108.04 ? 445 LEU B O   1 
ATOM   6982  C CB  . LEU B 1 437 ? -69.735 75.635  18.094 1.00 137.34 ? 445 LEU B CB  1 
ATOM   6983  C CG  . LEU B 1 437 ? -70.499 74.473  18.755 1.00 119.14 ? 445 LEU B CG  1 
ATOM   6984  C CD1 . LEU B 1 437 ? -71.260 73.659  17.746 1.00 128.37 ? 445 LEU B CD1 1 
ATOM   6985  C CD2 . LEU B 1 437 ? -69.676 73.583  19.674 1.00 126.51 ? 445 LEU B CD2 1 
ATOM   6986  N N   . LYS B 1 438 ? -71.847 78.177  18.886 1.00 139.14 ? 446 LYS B N   1 
ATOM   6987  C CA  . LYS B 1 438 ? -72.952 78.649  19.713 1.00 125.68 ? 446 LYS B CA  1 
ATOM   6988  C C   . LYS B 1 438 ? -74.115 79.020  18.784 1.00 135.43 ? 446 LYS B C   1 
ATOM   6989  O O   . LYS B 1 438 ? -75.145 78.340  18.736 1.00 149.78 ? 446 LYS B O   1 
ATOM   6990  C CB  . LYS B 1 438 ? -72.422 79.711  20.693 1.00 80.14  ? 446 LYS B CB  1 
ATOM   6991  C CG  . LYS B 1 438 ? -73.431 80.136  21.758 1.00 79.78  ? 446 LYS B CG  1 
ATOM   6992  C CD  . LYS B 1 438 ? -73.401 81.501  22.441 1.00 83.59  ? 446 LYS B CD  1 
ATOM   6993  C CE  . LYS B 1 438 ? -74.112 81.392  23.789 1.00 110.35 ? 446 LYS B CE  1 
ATOM   6994  N NZ  . LYS B 1 438 ? -73.861 82.360  24.871 1.00 95.39  ? 446 LYS B NZ  1 
ATOM   6995  N N   . GLU B 1 439 ? -73.848 80.020  17.924 1.00 125.26 ? 447 GLU B N   1 
ATOM   6996  C CA  . GLU B 1 439 ? -74.705 80.456  16.826 1.00 114.76 ? 447 GLU B CA  1 
ATOM   6997  C C   . GLU B 1 439 ? -75.339 79.210  16.221 1.00 109.57 ? 447 GLU B C   1 
ATOM   6998  O O   . GLU B 1 439 ? -76.557 78.997  16.317 1.00 84.17  ? 447 GLU B O   1 
ATOM   6999  C CB  . GLU B 1 439 ? -73.881 81.207  15.757 1.00 104.58 ? 447 GLU B CB  1 
ATOM   7000  C CG  . GLU B 1 439 ? -74.035 82.727  15.773 1.00 86.73  ? 447 GLU B CG  1 
ATOM   7001  C CD  . GLU B 1 439 ? -72.730 83.504  15.687 1.00 106.25 ? 447 GLU B CD  1 
ATOM   7002  O OE1 . GLU B 1 439 ? -72.577 84.243  14.700 1.00 95.03  ? 447 GLU B OE1 1 
ATOM   7003  O OE2 . GLU B 1 439 ? -71.892 83.372  16.622 1.00 115.10 ? 447 GLU B OE2 1 
ATOM   7004  N N   . PHE B 1 440 ? -74.462 78.371  15.661 1.00 85.85  ? 448 PHE B N   1 
ATOM   7005  C CA  . PHE B 1 440 ? -74.845 77.093  15.091 1.00 94.54  ? 448 PHE B CA  1 
ATOM   7006  C C   . PHE B 1 440 ? -75.672 76.228  16.060 1.00 91.26  ? 448 PHE B C   1 
ATOM   7007  O O   . PHE B 1 440 ? -76.770 75.793  15.691 1.00 70.38  ? 448 PHE B O   1 
ATOM   7008  C CB  . PHE B 1 440 ? -73.571 76.389  14.625 1.00 102.57 ? 448 PHE B CB  1 
ATOM   7009  C CG  . PHE B 1 440 ? -73.830 75.171  13.759 1.00 123.40 ? 448 PHE B CG  1 
ATOM   7010  C CD1 . PHE B 1 440 ? -74.210 73.937  14.290 1.00 124.54 ? 448 PHE B CD1 1 
ATOM   7011  C CD2 . PHE B 1 440 ? -73.672 75.290  12.384 1.00 138.73 ? 448 PHE B CD2 1 
ATOM   7012  C CE1 . PHE B 1 440 ? -74.436 72.852  13.450 1.00 130.79 ? 448 PHE B CE1 1 
ATOM   7013  C CE2 . PHE B 1 440 ? -73.881 74.202  11.557 1.00 149.09 ? 448 PHE B CE2 1 
ATOM   7014  C CZ  . PHE B 1 440 ? -74.280 72.988  12.075 1.00 152.06 ? 448 PHE B CZ  1 
ATOM   7015  N N   . LYS B 1 441 ? -75.161 75.932  17.271 1.00 95.02  ? 449 LYS B N   1 
ATOM   7016  C CA  . LYS B 1 441 ? -75.935 75.232  18.301 1.00 117.34 ? 449 LYS B CA  1 
ATOM   7017  C C   . LYS B 1 441 ? -77.307 75.903  18.477 1.00 119.87 ? 449 LYS B C   1 
ATOM   7018  O O   . LYS B 1 441 ? -78.336 75.209  18.609 1.00 109.09 ? 449 LYS B O   1 
ATOM   7019  C CB  . LYS B 1 441 ? -75.233 75.181  19.666 1.00 115.55 ? 449 LYS B CB  1 
ATOM   7020  C CG  . LYS B 1 441 ? -74.194 74.096  19.938 1.00 118.98 ? 449 LYS B CG  1 
ATOM   7021  C CD  . LYS B 1 441 ? -73.502 73.983  21.299 1.00 109.98 ? 449 LYS B CD  1 
ATOM   7022  C CE  . LYS B 1 441 ? -72.669 75.190  21.774 1.00 135.64 ? 449 LYS B CE  1 
ATOM   7023  N NZ  . LYS B 1 441 ? -71.281 75.107  22.271 1.00 89.06  ? 449 LYS B NZ  1 
ATOM   7024  N N   . GLU B 1 442 ? -77.296 77.252  18.411 1.00 110.04 ? 450 GLU B N   1 
ATOM   7025  C CA  . GLU B 1 442 ? -78.497 77.990  18.761 1.00 108.68 ? 450 GLU B CA  1 
ATOM   7026  C C   . GLU B 1 442 ? -79.544 77.853  17.666 1.00 106.71 ? 450 GLU B C   1 
ATOM   7027  O O   . GLU B 1 442 ? -80.699 77.503  17.941 1.00 97.41  ? 450 GLU B O   1 
ATOM   7028  C CB  . GLU B 1 442 ? -78.259 79.390  19.321 1.00 105.59 ? 450 GLU B CB  1 
ATOM   7029  C CG  . GLU B 1 442 ? -77.744 79.267  20.752 1.00 133.61 ? 450 GLU B CG  1 
ATOM   7030  C CD  . GLU B 1 442 ? -77.073 80.482  21.327 1.00 139.66 ? 450 GLU B CD  1 
ATOM   7031  O OE1 . GLU B 1 442 ? -77.058 81.523  20.625 1.00 152.43 ? 450 GLU B OE1 1 
ATOM   7032  O OE2 . GLU B 1 442 ? -76.618 80.334  22.478 1.00 93.35  ? 450 GLU B OE2 1 
ATOM   7033  N N   . ARG B 1 443 ? -79.077 78.038  16.434 1.00 86.49  ? 451 ARG B N   1 
ATOM   7034  C CA  . ARG B 1 443 ? -79.920 77.927  15.250 1.00 92.06  ? 451 ARG B CA  1 
ATOM   7035  C C   . ARG B 1 443 ? -80.488 76.513  15.142 1.00 94.84  ? 451 ARG B C   1 
ATOM   7036  O O   . ARG B 1 443 ? -81.590 76.354  14.644 1.00 91.63  ? 451 ARG B O   1 
ATOM   7037  C CB  . ARG B 1 443 ? -79.121 78.279  13.991 1.00 95.00  ? 451 ARG B CB  1 
ATOM   7038  C CG  . ARG B 1 443 ? -80.086 78.697  12.897 1.00 111.62 ? 451 ARG B CG  1 
ATOM   7039  C CD  . ARG B 1 443 ? -80.967 79.896  13.244 1.00 112.91 ? 451 ARG B CD  1 
ATOM   7040  N NE  . ARG B 1 443 ? -80.490 81.132  12.618 1.00 96.33  ? 451 ARG B NE  1 
ATOM   7041  C CZ  . ARG B 1 443 ? -80.191 81.302  11.325 1.00 128.38 ? 451 ARG B CZ  1 
ATOM   7042  N NH1 . ARG B 1 443 ? -80.404 80.373  10.402 1.00 131.34 ? 451 ARG B NH1 1 
ATOM   7043  N NH2 . ARG B 1 443 ? -79.688 82.457  10.933 1.00 148.16 ? 451 ARG B NH2 1 
ATOM   7044  N N   . LEU B 1 444 ? -79.711 75.511  15.592 1.00 94.37  ? 452 LEU B N   1 
ATOM   7045  C CA  . LEU B 1 444 ? -80.122 74.120  15.716 1.00 82.36  ? 452 LEU B CA  1 
ATOM   7046  C C   . LEU B 1 444 ? -81.397 73.994  16.545 1.00 81.67  ? 452 LEU B C   1 
ATOM   7047  O O   . LEU B 1 444 ? -82.286 73.221  16.170 1.00 110.87 ? 452 LEU B O   1 
ATOM   7048  C CB  . LEU B 1 444 ? -79.006 73.239  16.276 1.00 86.00  ? 452 LEU B CB  1 
ATOM   7049  C CG  . LEU B 1 444 ? -79.316 71.741  16.281 1.00 97.35  ? 452 LEU B CG  1 
ATOM   7050  C CD1 . LEU B 1 444 ? -79.729 71.391  14.864 1.00 131.10 ? 452 LEU B CD1 1 
ATOM   7051  C CD2 . LEU B 1 444 ? -78.127 70.842  16.630 1.00 109.14 ? 452 LEU B CD2 1 
ATOM   7052  N N   . ALA B 1 445 ? -81.526 74.789  17.618 1.00 77.49  ? 453 ALA B N   1 
ATOM   7053  C CA  . ALA B 1 445 ? -82.804 74.936  18.310 1.00 86.82  ? 453 ALA B CA  1 
ATOM   7054  C C   . ALA B 1 445 ? -83.822 75.734  17.496 1.00 117.00 ? 453 ALA B C   1 
ATOM   7055  O O   . ALA B 1 445 ? -85.033 75.506  17.658 1.00 119.22 ? 453 ALA B O   1 
ATOM   7056  C CB  . ALA B 1 445 ? -82.671 75.426  19.722 1.00 68.98  ? 453 ALA B CB  1 
ATOM   7057  N N   . GLY B 1 446 ? -83.343 76.583  16.566 1.00 126.12 ? 454 GLY B N   1 
ATOM   7058  C CA  . GLY B 1 446 ? -84.182 77.272  15.579 1.00 133.05 ? 454 GLY B CA  1 
ATOM   7059  C C   . GLY B 1 446 ? -85.280 76.384  14.975 1.00 143.38 ? 454 GLY B C   1 
ATOM   7060  O O   . GLY B 1 446 ? -85.036 75.210  14.694 1.00 184.07 ? 454 GLY B O   1 
ATOM   7061  N N   . ASP B 1 447 ? -86.505 76.918  14.850 1.00 129.03 ? 455 ASP B N   1 
ATOM   7062  C CA  . ASP B 1 447 ? -87.669 76.072  14.583 1.00 109.30 ? 455 ASP B CA  1 
ATOM   7063  C C   . ASP B 1 447 ? -87.564 75.364  13.229 1.00 116.96 ? 455 ASP B C   1 
ATOM   7064  O O   . ASP B 1 447 ? -87.833 74.153  13.129 1.00 93.49  ? 455 ASP B O   1 
ATOM   7065  C CB  . ASP B 1 447 ? -88.963 76.743  14.992 1.00 76.32  ? 455 ASP B CB  1 
ATOM   7066  C CG  . ASP B 1 447 ? -88.945 76.989  16.488 1.00 115.78 ? 455 ASP B CG  1 
ATOM   7067  O OD1 . ASP B 1 447 ? -87.850 77.322  17.003 1.00 130.48 ? 455 ASP B OD1 1 
ATOM   7068  O OD2 . ASP B 1 447 ? -90.000 76.828  17.124 1.00 117.65 ? 455 ASP B OD2 1 
ATOM   7069  N N   . LYS B 1 448 ? -87.081 76.096  12.211 1.00 95.49  ? 456 LYS B N   1 
ATOM   7070  C CA  . LYS B 1 448 ? -86.941 75.549  10.871 1.00 94.44  ? 456 LYS B CA  1 
ATOM   7071  C C   . LYS B 1 448 ? -86.227 74.204  10.970 1.00 132.67 ? 456 LYS B C   1 
ATOM   7072  O O   . LYS B 1 448 ? -86.693 73.184  10.474 1.00 196.16 ? 456 LYS B O   1 
ATOM   7073  C CB  . LYS B 1 448 ? -86.152 76.583  10.067 1.00 105.48 ? 456 LYS B CB  1 
ATOM   7074  C CG  . LYS B 1 448 ? -86.171 76.579  8.529  1.00 96.83  ? 456 LYS B CG  1 
ATOM   7075  C CD  . LYS B 1 448 ? -85.750 77.972  8.033  1.00 87.38  ? 456 LYS B CD  1 
ATOM   7076  C CE  . LYS B 1 448 ? -86.498 78.678  6.906  1.00 82.91  ? 456 LYS B CE  1 
ATOM   7077  N NZ  . LYS B 1 448 ? -86.374 77.952  5.640  1.00 84.77  ? 456 LYS B NZ  1 
ATOM   7078  N N   . TYR B 1 449 ? -85.116 74.196  11.695 1.00 128.56 ? 457 TYR B N   1 
ATOM   7079  C CA  . TYR B 1 449 ? -84.208 73.074  11.775 1.00 111.15 ? 457 TYR B CA  1 
ATOM   7080  C C   . TYR B 1 449 ? -84.757 71.971  12.667 1.00 112.82 ? 457 TYR B C   1 
ATOM   7081  O O   . TYR B 1 449 ? -84.734 70.809  12.267 1.00 110.72 ? 457 TYR B O   1 
ATOM   7082  C CB  . TYR B 1 449 ? -82.893 73.663  12.288 1.00 107.14 ? 457 TYR B CB  1 
ATOM   7083  C CG  . TYR B 1 449 ? -82.286 74.499  11.180 1.00 121.30 ? 457 TYR B CG  1 
ATOM   7084  C CD1 . TYR B 1 449 ? -81.965 73.885  9.967  1.00 136.13 ? 457 TYR B CD1 1 
ATOM   7085  C CD2 . TYR B 1 449 ? -82.119 75.875  11.296 1.00 119.15 ? 457 TYR B CD2 1 
ATOM   7086  C CE1 . TYR B 1 449 ? -81.424 74.598  8.912  1.00 114.75 ? 457 TYR B CE1 1 
ATOM   7087  C CE2 . TYR B 1 449 ? -81.603 76.601  10.228 1.00 148.06 ? 457 TYR B CE2 1 
ATOM   7088  C CZ  . TYR B 1 449 ? -81.226 75.957  9.057  1.00 130.67 ? 457 TYR B CZ  1 
ATOM   7089  O OH  . TYR B 1 449 ? -80.699 76.647  8.018  1.00 99.45  ? 457 TYR B OH  1 
ATOM   7090  N N   . GLN B 1 450 ? -85.189 72.340  13.890 1.00 107.68 ? 458 GLN B N   1 
ATOM   7091  C CA  . GLN B 1 450 ? -85.846 71.463  14.846 1.00 117.43 ? 458 GLN B CA  1 
ATOM   7092  C C   . GLN B 1 450 ? -86.837 70.522  14.146 1.00 118.53 ? 458 GLN B C   1 
ATOM   7093  O O   . GLN B 1 450 ? -86.943 69.342  14.503 1.00 113.09 ? 458 GLN B O   1 
ATOM   7094  C CB  . GLN B 1 450 ? -86.652 72.315  15.833 1.00 115.57 ? 458 GLN B CB  1 
ATOM   7095  C CG  . GLN B 1 450 ? -85.865 72.891  16.997 1.00 126.93 ? 458 GLN B CG  1 
ATOM   7096  C CD  . GLN B 1 450 ? -85.199 71.855  17.872 1.00 111.83 ? 458 GLN B CD  1 
ATOM   7097  O OE1 . GLN B 1 450 ? -84.222 72.172  18.558 1.00 106.81 ? 458 GLN B OE1 1 
ATOM   7098  N NE2 . GLN B 1 450 ? -85.796 70.679  18.012 1.00 87.02  ? 458 GLN B NE2 1 
ATOM   7099  N N   . ALA B 1 451 ? -87.552 71.068  13.153 1.00 107.11 ? 459 ALA B N   1 
ATOM   7100  C CA  . ALA B 1 451 ? -88.498 70.282  12.375 1.00 129.98 ? 459 ALA B CA  1 
ATOM   7101  C C   . ALA B 1 451 ? -87.813 69.141  11.605 1.00 107.62 ? 459 ALA B C   1 
ATOM   7102  O O   . ALA B 1 451 ? -88.202 67.967  11.733 1.00 88.77  ? 459 ALA B O   1 
ATOM   7103  C CB  . ALA B 1 451 ? -89.303 71.198  11.470 1.00 135.52 ? 459 ALA B CB  1 
ATOM   7104  N N   . ALA B 1 452 ? -86.757 69.491  10.846 1.00 120.69 ? 460 ALA B N   1 
ATOM   7105  C CA  . ALA B 1 452 ? -85.985 68.548  10.035 1.00 115.60 ? 460 ALA B CA  1 
ATOM   7106  C C   . ALA B 1 452 ? -85.350 67.481  10.932 1.00 123.56 ? 460 ALA B C   1 
ATOM   7107  O O   . ALA B 1 452 ? -85.390 66.286  10.640 1.00 112.19 ? 460 ALA B O   1 
ATOM   7108  C CB  . ALA B 1 452 ? -84.896 69.280  9.252  1.00 69.02  ? 460 ALA B CB  1 
ATOM   7109  N N   . VAL B 1 453 ? -84.770 67.967  12.032 1.00 104.55 ? 461 VAL B N   1 
ATOM   7110  C CA  . VAL B 1 453 ? -84.042 67.148  12.970 1.00 75.15  ? 461 VAL B CA  1 
ATOM   7111  C C   . VAL B 1 453 ? -84.997 66.175  13.642 1.00 98.61  ? 461 VAL B C   1 
ATOM   7112  O O   . VAL B 1 453 ? -84.614 65.012  13.790 1.00 81.76  ? 461 VAL B O   1 
ATOM   7113  C CB  . VAL B 1 453 ? -83.268 68.065  13.930 1.00 72.65  ? 461 VAL B CB  1 
ATOM   7114  C CG1 . VAL B 1 453 ? -83.045 67.469  15.348 1.00 70.96  ? 461 VAL B CG1 1 
ATOM   7115  C CG2 . VAL B 1 453 ? -81.997 68.514  13.183 1.00 43.24  ? 461 VAL B CG2 1 
ATOM   7116  N N   . GLN B 1 454 ? -86.224 66.628  13.980 1.00 106.18 ? 462 GLN B N   1 
ATOM   7117  C CA  . GLN B 1 454 ? -87.183 65.734  14.618 1.00 87.56  ? 462 GLN B CA  1 
ATOM   7118  C C   . GLN B 1 454 ? -87.583 64.616  13.650 1.00 88.97  ? 462 GLN B C   1 
ATOM   7119  O O   . GLN B 1 454 ? -87.689 63.446  14.056 1.00 103.34 ? 462 GLN B O   1 
ATOM   7120  C CB  . GLN B 1 454 ? -88.329 66.320  15.442 1.00 73.42  ? 462 GLN B CB  1 
ATOM   7121  C CG  . GLN B 1 454 ? -88.699 65.325  16.538 1.00 99.24  ? 462 GLN B CG  1 
ATOM   7122  C CD  . GLN B 1 454 ? -89.857 65.668  17.462 1.00 133.23 ? 462 GLN B CD  1 
ATOM   7123  O OE1 . GLN B 1 454 ? -90.585 66.657  17.297 1.00 96.97  ? 462 GLN B OE1 1 
ATOM   7124  N NE2 . GLN B 1 454 ? -90.058 64.819  18.465 1.00 142.51 ? 462 GLN B NE2 1 
ATOM   7125  N N   . ALA B 1 455 ? -87.729 64.965  12.361 1.00 84.54  ? 463 ALA B N   1 
ATOM   7126  C CA  . ALA B 1 455 ? -88.025 63.949  11.356 1.00 72.76  ? 463 ALA B CA  1 
ATOM   7127  C C   . ALA B 1 455 ? -86.937 62.891  11.391 1.00 104.40 ? 463 ALA B C   1 
ATOM   7128  O O   . ALA B 1 455 ? -87.192 61.776  11.851 1.00 81.23  ? 463 ALA B O   1 
ATOM   7129  C CB  . ALA B 1 455 ? -88.128 64.508  9.972  1.00 43.31  ? 463 ALA B CB  1 
ATOM   7130  N N   . LEU B 1 456 ? -85.705 63.320  11.066 1.00 125.01 ? 464 LEU B N   1 
ATOM   7131  C CA  . LEU B 1 456 ? -84.572 62.418  10.960 1.00 110.28 ? 464 LEU B CA  1 
ATOM   7132  C C   . LEU B 1 456 ? -84.449 61.602  12.246 1.00 113.97 ? 464 LEU B C   1 
ATOM   7133  O O   . LEU B 1 456 ? -84.337 60.380  12.162 1.00 104.36 ? 464 LEU B O   1 
ATOM   7134  C CB  . LEU B 1 456 ? -83.298 63.197  10.639 1.00 93.49  ? 464 LEU B CB  1 
ATOM   7135  C CG  . LEU B 1 456 ? -82.011 62.376  10.495 1.00 101.04 ? 464 LEU B CG  1 
ATOM   7136  C CD1 . LEU B 1 456 ? -82.313 61.299  9.483  1.00 106.89 ? 464 LEU B CD1 1 
ATOM   7137  C CD2 . LEU B 1 456 ? -80.805 63.185  9.985  1.00 86.78  ? 464 LEU B CD2 1 
ATOM   7138  N N   . ARG B 1 457 ? -84.536 62.279  13.400 1.00 99.18  ? 465 ARG B N   1 
ATOM   7139  C CA  . ARG B 1 457 ? -84.381 61.625  14.684 1.00 113.68 ? 465 ARG B CA  1 
ATOM   7140  C C   . ARG B 1 457 ? -85.337 60.437  14.769 1.00 114.07 ? 465 ARG B C   1 
ATOM   7141  O O   . ARG B 1 457 ? -84.929 59.322  15.129 1.00 97.29  ? 465 ARG B O   1 
ATOM   7142  C CB  . ARG B 1 457 ? -84.544 62.617  15.848 1.00 121.34 ? 465 ARG B CB  1 
ATOM   7143  C CG  . ARG B 1 457 ? -84.331 61.968  17.216 1.00 89.57  ? 465 ARG B CG  1 
ATOM   7144  C CD  . ARG B 1 457 ? -84.377 63.016  18.333 1.00 90.35  ? 465 ARG B CD  1 
ATOM   7145  N NE  . ARG B 1 457 ? -85.795 63.265  18.588 1.00 123.40 ? 465 ARG B NE  1 
ATOM   7146  C CZ  . ARG B 1 457 ? -86.461 62.750  19.619 1.00 119.24 ? 465 ARG B CZ  1 
ATOM   7147  N NH1 . ARG B 1 457 ? -85.839 62.450  20.741 1.00 85.43  ? 465 ARG B NH1 1 
ATOM   7148  N NH2 . ARG B 1 457 ? -87.782 62.629  19.573 1.00 125.58 ? 465 ARG B NH2 1 
ATOM   7149  N N   . GLU B 1 458 ? -86.601 60.701  14.408 1.00 110.89 ? 466 GLU B N   1 
ATOM   7150  C CA  . GLU B 1 458 ? -87.667 59.714  14.473 1.00 115.84 ? 466 GLU B CA  1 
ATOM   7151  C C   . GLU B 1 458 ? -87.296 58.463  13.686 1.00 115.33 ? 466 GLU B C   1 
ATOM   7152  O O   . GLU B 1 458 ? -87.326 57.350  14.217 1.00 155.63 ? 466 GLU B O   1 
ATOM   7153  C CB  . GLU B 1 458 ? -89.026 60.270  14.052 1.00 87.39  ? 466 GLU B CB  1 
ATOM   7154  C CG  . GLU B 1 458 ? -89.953 60.398  15.256 1.00 116.60 ? 466 GLU B CG  1 
ATOM   7155  C CD  . GLU B 1 458 ? -90.905 61.528  14.984 1.00 141.32 ? 466 GLU B CD  1 
ATOM   7156  O OE1 . GLU B 1 458 ? -91.877 61.311  14.230 1.00 139.53 ? 466 GLU B OE1 1 
ATOM   7157  O OE2 . GLU B 1 458 ? -90.618 62.630  15.496 1.00 167.99 ? 466 GLU B OE2 1 
ATOM   7158  N N   . GLU B 1 459 ? -86.884 58.681  12.432 1.00 105.27 ? 467 GLU B N   1 
ATOM   7159  C CA  . GLU B 1 459 ? -86.533 57.603  11.517 1.00 93.42  ? 467 GLU B CA  1 
ATOM   7160  C C   . GLU B 1 459 ? -85.401 56.794  12.137 1.00 97.44  ? 467 GLU B C   1 
ATOM   7161  O O   . GLU B 1 459 ? -85.476 55.564  12.217 1.00 97.10  ? 467 GLU B O   1 
ATOM   7162  C CB  . GLU B 1 459 ? -86.140 58.207  10.168 1.00 81.88  ? 467 GLU B CB  1 
ATOM   7163  C CG  . GLU B 1 459 ? -86.887 57.574  8.994  1.00 100.03 ? 467 GLU B CG  1 
ATOM   7164  C CD  . GLU B 1 459 ? -86.383 58.029  7.634  1.00 119.55 ? 467 GLU B CD  1 
ATOM   7165  O OE1 . GLU B 1 459 ? -86.647 59.202  7.293  1.00 109.20 ? 467 GLU B OE1 1 
ATOM   7166  O OE2 . GLU B 1 459 ? -85.751 57.215  6.920  1.00 100.66 ? 467 GLU B OE2 1 
ATOM   7167  N N   . VAL B 1 460 ? -84.371 57.519  12.597 1.00 98.70  ? 468 VAL B N   1 
ATOM   7168  C CA  . VAL B 1 460 ? -83.177 56.931  13.181 1.00 90.48  ? 468 VAL B CA  1 
ATOM   7169  C C   . VAL B 1 460 ? -83.561 56.048  14.368 1.00 85.08  ? 468 VAL B C   1 
ATOM   7170  O O   . VAL B 1 460 ? -83.149 54.887  14.439 1.00 99.98  ? 468 VAL B O   1 
ATOM   7171  C CB  . VAL B 1 460 ? -82.188 58.034  13.586 1.00 85.60  ? 468 VAL B CB  1 
ATOM   7172  C CG1 . VAL B 1 460 ? -81.096 57.510  14.493 1.00 87.77  ? 468 VAL B CG1 1 
ATOM   7173  C CG2 . VAL B 1 460 ? -81.557 58.664  12.363 1.00 124.74 ? 468 VAL B CG2 1 
ATOM   7174  N N   . GLU B 1 461 ? -84.368 56.593  15.276 1.00 61.89  ? 469 GLU B N   1 
ATOM   7175  C CA  . GLU B 1 461 ? -84.773 55.824  16.449 1.00 89.57  ? 469 GLU B CA  1 
ATOM   7176  C C   . GLU B 1 461 ? -85.568 54.572  16.046 1.00 102.52 ? 469 GLU B C   1 
ATOM   7177  O O   . GLU B 1 461 ? -85.324 53.479  16.569 1.00 95.44  ? 469 GLU B O   1 
ATOM   7178  C CB  . GLU B 1 461 ? -85.482 56.664  17.515 1.00 96.01  ? 469 GLU B CB  1 
ATOM   7179  C CG  . GLU B 1 461 ? -84.631 57.790  18.088 1.00 94.77  ? 469 GLU B CG  1 
ATOM   7180  C CD  . GLU B 1 461 ? -85.312 58.645  19.136 1.00 99.69  ? 469 GLU B CD  1 
ATOM   7181  O OE1 . GLU B 1 461 ? -86.410 58.313  19.597 1.00 133.82 ? 469 GLU B OE1 1 
ATOM   7182  O OE2 . GLU B 1 461 ? -84.741 59.681  19.492 1.00 80.17  ? 469 GLU B OE2 1 
ATOM   7183  N N   . SER B 1 462 ? -86.521 54.711  15.110 1.00 108.81 ? 470 SER B N   1 
ATOM   7184  C CA  . SER B 1 462 ? -87.330 53.554  14.744 1.00 103.44 ? 470 SER B CA  1 
ATOM   7185  C C   . SER B 1 462 ? -86.442 52.450  14.165 1.00 99.22  ? 470 SER B C   1 
ATOM   7186  O O   . SER B 1 462 ? -86.621 51.290  14.509 1.00 129.73 ? 470 SER B O   1 
ATOM   7187  C CB  . SER B 1 462 ? -88.482 53.886  13.853 1.00 92.50  ? 470 SER B CB  1 
ATOM   7188  O OG  . SER B 1 462 ? -88.051 54.820  12.872 1.00 133.08 ? 470 SER B OG  1 
ATOM   7189  N N   . PHE B 1 463 ? -85.439 52.819  13.364 1.00 82.73  ? 471 PHE B N   1 
ATOM   7190  C CA  . PHE B 1 463 ? -84.501 51.853  12.806 1.00 93.20  ? 471 PHE B CA  1 
ATOM   7191  C C   . PHE B 1 463 ? -83.690 51.135  13.885 1.00 102.90 ? 471 PHE B C   1 
ATOM   7192  O O   . PHE B 1 463 ? -83.552 49.907  13.876 1.00 102.89 ? 471 PHE B O   1 
ATOM   7193  C CB  . PHE B 1 463 ? -83.574 52.563  11.820 1.00 86.46  ? 471 PHE B CB  1 
ATOM   7194  C CG  . PHE B 1 463 ? -82.434 51.698  11.305 1.00 105.22 ? 471 PHE B CG  1 
ATOM   7195  C CD1 . PHE B 1 463 ? -82.616 50.354  10.945 1.00 97.44  ? 471 PHE B CD1 1 
ATOM   7196  C CD2 . PHE B 1 463 ? -81.154 52.239  11.252 1.00 126.79 ? 471 PHE B CD2 1 
ATOM   7197  C CE1 . PHE B 1 463 ? -81.550 49.597  10.489 1.00 133.84 ? 471 PHE B CE1 1 
ATOM   7198  C CE2 . PHE B 1 463 ? -80.093 51.474  10.788 1.00 134.28 ? 471 PHE B CE2 1 
ATOM   7199  C CZ  . PHE B 1 463 ? -80.288 50.145  10.427 1.00 144.24 ? 471 PHE B CZ  1 
ATOM   7200  N N   . ALA B 1 464 ? -83.160 51.915  14.822 1.00 91.34  ? 472 ALA B N   1 
ATOM   7201  C CA  . ALA B 1 464 ? -82.371 51.365  15.918 1.00 88.84  ? 472 ALA B CA  1 
ATOM   7202  C C   . ALA B 1 464 ? -83.208 50.441  16.804 1.00 92.87  ? 472 ALA B C   1 
ATOM   7203  O O   . ALA B 1 464 ? -82.672 49.439  17.289 1.00 85.24  ? 472 ALA B O   1 
ATOM   7204  C CB  . ALA B 1 464 ? -81.823 52.506  16.741 1.00 111.74 ? 472 ALA B CB  1 
ATOM   7205  N N   . SER B 1 465 ? -84.474 50.845  17.061 1.00 93.43  ? 473 SER B N   1 
ATOM   7206  C CA  . SER B 1 465 ? -85.418 50.106  17.881 1.00 102.44 ? 473 SER B CA  1 
ATOM   7207  C C   . SER B 1 465 ? -85.628 48.699  17.355 1.00 103.94 ? 473 SER B C   1 
ATOM   7208  O O   . SER B 1 465 ? -86.087 47.858  18.108 1.00 118.26 ? 473 SER B O   1 
ATOM   7209  C CB  . SER B 1 465 ? -86.739 50.786  17.972 1.00 105.67 ? 473 SER B CB  1 
ATOM   7210  O OG  . SER B 1 465 ? -86.755 51.664  19.083 1.00 137.91 ? 473 SER B OG  1 
ATOM   7211  N N   . LEU B 1 466 ? -85.306 48.459  16.082 1.00 83.45  ? 474 LEU B N   1 
ATOM   7212  C CA  . LEU B 1 466 ? -85.609 47.178  15.473 1.00 71.51  ? 474 LEU B CA  1 
ATOM   7213  C C   . LEU B 1 466 ? -84.676 46.077  15.975 1.00 75.60  ? 474 LEU B C   1 
ATOM   7214  O O   . LEU B 1 466 ? -84.955 44.904  15.763 1.00 106.10 ? 474 LEU B O   1 
ATOM   7215  C CB  . LEU B 1 466 ? -85.483 47.289  13.958 1.00 72.88  ? 474 LEU B CB  1 
ATOM   7216  C CG  . LEU B 1 466 ? -86.565 48.054  13.213 1.00 80.02  ? 474 LEU B CG  1 
ATOM   7217  C CD1 . LEU B 1 466 ? -86.103 48.194  11.772 1.00 71.75  ? 474 LEU B CD1 1 
ATOM   7218  C CD2 . LEU B 1 466 ? -87.842 47.240  13.289 1.00 76.77  ? 474 LEU B CD2 1 
ATOM   7219  N N   . PHE B 1 467 ? -83.540 46.445  16.579 1.00 73.22  ? 475 PHE B N   1 
ATOM   7220  C CA  . PHE B 1 467 ? -82.555 45.453  16.994 1.00 93.32  ? 475 PHE B CA  1 
ATOM   7221  C C   . PHE B 1 467 ? -82.469 45.353  18.525 1.00 109.51 ? 475 PHE B C   1 
ATOM   7222  O O   . PHE B 1 467 ? -82.869 46.290  19.226 1.00 113.94 ? 475 PHE B O   1 
ATOM   7223  C CB  . PHE B 1 467 ? -81.175 45.826  16.464 1.00 88.77  ? 475 PHE B CB  1 
ATOM   7224  C CG  . PHE B 1 467 ? -81.094 46.141  14.984 1.00 83.28  ? 475 PHE B CG  1 
ATOM   7225  C CD1 . PHE B 1 467 ? -81.467 47.400  14.471 1.00 80.35  ? 475 PHE B CD1 1 
ATOM   7226  C CD2 . PHE B 1 467 ? -80.535 45.197  14.130 1.00 80.51  ? 475 PHE B CD2 1 
ATOM   7227  C CE1 . PHE B 1 467 ? -81.310 47.678  13.109 1.00 93.86  ? 475 PHE B CE1 1 
ATOM   7228  C CE2 . PHE B 1 467 ? -80.416 45.461  12.768 1.00 84.30  ? 475 PHE B CE2 1 
ATOM   7229  C CZ  . PHE B 1 467 ? -80.778 46.709  12.255 1.00 88.99  ? 475 PHE B CZ  1 
ATOM   7230  N N   . PRO B 1 468 ? -81.922 44.244  19.101 1.00 106.32 ? 476 PRO B N   1 
ATOM   7231  C CA  . PRO B 1 468 ? -81.984 44.034  20.553 1.00 97.89  ? 476 PRO B CA  1 
ATOM   7232  C C   . PRO B 1 468 ? -80.906 44.886  21.216 1.00 125.57 ? 476 PRO B C   1 
ATOM   7233  O O   . PRO B 1 468 ? -79.991 45.396  20.528 1.00 150.19 ? 476 PRO B O   1 
ATOM   7234  C CB  . PRO B 1 468 ? -81.717 42.515  20.681 1.00 83.39  ? 476 PRO B CB  1 
ATOM   7235  C CG  . PRO B 1 468 ? -80.761 42.204  19.526 1.00 83.02  ? 476 PRO B CG  1 
ATOM   7236  C CD  . PRO B 1 468 ? -81.176 43.170  18.403 1.00 99.28  ? 476 PRO B CD  1 
ATOM   7237  N N   . LEU B 1 469 ? -81.002 44.997  22.555 1.00 101.37 ? 477 LEU B N   1 
ATOM   7238  C CA  . LEU B 1 469 ? -80.055 45.827  23.296 1.00 119.44 ? 477 LEU B CA  1 
ATOM   7239  C C   . LEU B 1 469 ? -79.385 45.032  24.413 1.00 108.31 ? 477 LEU B C   1 
ATOM   7240  O O   . LEU B 1 469 ? -79.964 44.877  25.484 1.00 102.80 ? 477 LEU B O   1 
ATOM   7241  C CB  . LEU B 1 469 ? -80.761 47.060  23.848 1.00 144.93 ? 477 LEU B CB  1 
ATOM   7242  C CG  . LEU B 1 469 ? -79.852 48.080  24.537 1.00 128.41 ? 477 LEU B CG  1 
ATOM   7243  C CD1 . LEU B 1 469 ? -79.078 48.927  23.523 1.00 110.45 ? 477 LEU B CD1 1 
ATOM   7244  C CD2 . LEU B 1 469 ? -80.632 48.967  25.525 1.00 132.72 ? 477 LEU B CD2 1 
ATOM   7245  N N   . PRO B 1 470 ? -78.127 44.569  24.204 1.00 121.25 ? 478 PRO B N   1 
ATOM   7246  C CA  . PRO B 1 470 ? -77.504 43.585  25.088 1.00 126.37 ? 478 PRO B CA  1 
ATOM   7247  C C   . PRO B 1 470 ? -77.534 44.057  26.541 1.00 157.76 ? 478 PRO B C   1 
ATOM   7248  O O   . PRO B 1 470 ? -77.405 45.250  26.824 1.00 189.13 ? 478 PRO B O   1 
ATOM   7249  C CB  . PRO B 1 470 ? -76.049 43.498  24.562 1.00 133.38 ? 478 PRO B CB  1 
ATOM   7250  C CG  . PRO B 1 470 ? -76.137 43.939  23.130 1.00 136.46 ? 478 PRO B CG  1 
ATOM   7251  C CD  . PRO B 1 470 ? -77.230 44.993  23.108 1.00 141.07 ? 478 PRO B CD  1 
ATOM   7252  N N   . GLY B 1 471 ? -77.657 43.096  27.454 1.00 137.89 ? 479 GLY B N   1 
ATOM   7253  C CA  . GLY B 1 471 ? -77.470 43.393  28.855 1.00 110.09 ? 479 GLY B CA  1 
ATOM   7254  C C   . GLY B 1 471 ? -78.837 43.765  29.360 1.00 126.39 ? 479 GLY B C   1 
ATOM   7255  O O   . GLY B 1 471 ? -79.122 44.943  29.470 1.00 130.63 ? 479 GLY B O   1 
ATOM   7256  N N   . LEU B 1 472 ? -79.705 42.754  29.349 1.00 168.41 ? 480 LEU B N   1 
ATOM   7257  C CA  . LEU B 1 472 ? -81.097 42.885  29.736 1.00 182.20 ? 480 LEU B CA  1 
ATOM   7258  C C   . LEU B 1 472 ? -81.161 42.883  31.281 1.00 155.64 ? 480 LEU B C   1 
ATOM   7259  O O   . LEU B 1 472 ? -82.041 42.133  31.816 1.00 125.68 ? 480 LEU B O   1 
ATOM   7260  C CB  . LEU B 1 472 ? -81.915 41.758  29.075 1.00 161.05 ? 480 LEU B CB  1 
ATOM   7261  C CG  . LEU B 1 472 ? -82.257 41.853  27.570 1.00 126.40 ? 480 LEU B CG  1 
ATOM   7262  C CD1 . LEU B 1 472 ? -82.774 43.247  27.168 1.00 115.04 ? 480 LEU B CD1 1 
ATOM   7263  C CD2 . LEU B 1 472 ? -81.173 41.322  26.572 1.00 81.07  ? 480 LEU B CD2 1 
ATOM   7264  O OXT . LEU B 1 472 ? -80.291 43.615  31.900 1.00 100.33 ? 480 LEU B OXT 1 
ATOM   7265  N N   . GLN C 1 1   ? -73.336 36.788  10.524 1.00 127.20 ? 9   GLN C N   1 
ATOM   7266  C CA  . GLN C 1 1   ? -72.506 36.123  9.490  1.00 153.20 ? 9   GLN C CA  1 
ATOM   7267  C C   . GLN C 1 1   ? -73.366 35.084  8.775  1.00 198.31 ? 9   GLN C C   1 
ATOM   7268  O O   . GLN C 1 1   ? -74.438 34.745  9.308  1.00 190.98 ? 9   GLN C O   1 
ATOM   7269  C CB  . GLN C 1 1   ? -71.297 35.454  10.137 1.00 30.00  ? 9   GLN C CB  1 
ATOM   7270  C CG  . GLN C 1 1   ? -70.120 35.268  9.192  1.00 30.00  ? 9   GLN C CG  1 
ATOM   7271  C CD  . GLN C 1 1   ? -70.194 33.951  8.460  1.00 30.00  ? 9   GLN C CD  1 
ATOM   7272  O OE1 . GLN C 1 1   ? -70.792 32.989  8.936  1.00 30.00  ? 9   GLN C OE1 1 
ATOM   7273  N NE2 . GLN C 1 1   ? -69.597 33.906  7.281  1.00 30.00  ? 9   GLN C NE2 1 
ATOM   7274  N N   . GLY C 1 2   ? -72.910 34.602  7.619  1.00 198.91 ? 10  GLY C N   1 
ATOM   7275  C CA  . GLY C 1 2   ? -73.654 33.557  6.900  1.00 137.12 ? 10  GLY C CA  1 
ATOM   7276  C C   . GLY C 1 2   ? -74.405 32.688  7.881  1.00 131.68 ? 10  GLY C C   1 
ATOM   7277  O O   . GLY C 1 2   ? -75.618 32.508  7.700  1.00 148.71 ? 10  GLY C O   1 
ATOM   7278  N N   . ASP C 1 3   ? -73.705 32.186  8.897  1.00 115.65 ? 11  ASP C N   1 
ATOM   7279  C CA  . ASP C 1 3   ? -74.355 31.327  9.917  1.00 123.64 ? 11  ASP C CA  1 
ATOM   7280  C C   . ASP C 1 3   ? -75.278 32.201  10.758 1.00 129.95 ? 11  ASP C C   1 
ATOM   7281  O O   . ASP C 1 3   ? -74.985 32.398  11.942 1.00 151.26 ? 11  ASP C O   1 
ATOM   7282  C CB  . ASP C 1 3   ? -73.333 30.595  10.784 1.00 123.78 ? 11  ASP C CB  1 
ATOM   7283  C CG  . ASP C 1 3   ? -73.909 29.384  11.496 1.00 140.58 ? 11  ASP C CG  1 
ATOM   7284  O OD1 . ASP C 1 3   ? -75.055 29.475  11.971 1.00 129.88 ? 11  ASP C OD1 1 
ATOM   7285  O OD2 . ASP C 1 3   ? -73.204 28.359  11.570 1.00 152.78 ? 11  ASP C OD2 1 
ATOM   7286  N N   . ALA C 1 4   ? -76.341 32.717  10.153 1.00 105.84 ? 12  ALA C N   1 
ATOM   7287  C CA  . ALA C 1 4   ? -77.308 33.491  10.948 1.00 89.49  ? 12  ALA C CA  1 
ATOM   7288  C C   . ALA C 1 4   ? -77.600 32.691  12.209 1.00 105.32 ? 12  ALA C C   1 
ATOM   7289  O O   . ALA C 1 4   ? -77.586 33.269  13.303 1.00 128.77 ? 12  ALA C O   1 
ATOM   7290  C CB  . ALA C 1 4   ? -78.550 33.705  10.144 1.00 58.99  ? 12  ALA C CB  1 
ATOM   7291  N N   . ASP C 1 5   ? -77.825 31.394  12.042 1.00 81.83  ? 13  ASP C N   1 
ATOM   7292  C CA  . ASP C 1 5   ? -78.092 30.531  13.213 1.00 93.24  ? 13  ASP C CA  1 
ATOM   7293  C C   . ASP C 1 5   ? -77.088 30.896  14.305 1.00 116.95 ? 13  ASP C C   1 
ATOM   7294  O O   . ASP C 1 5   ? -77.496 31.006  15.468 1.00 95.54  ? 13  ASP C O   1 
ATOM   7295  C CB  . ASP C 1 5   ? -78.051 29.057  12.816 1.00 108.08 ? 13  ASP C CB  1 
ATOM   7296  C CG  . ASP C 1 5   ? -78.330 28.832  11.342 1.00 119.43 ? 13  ASP C CG  1 
ATOM   7297  O OD1 . ASP C 1 5   ? -79.404 28.286  11.030 1.00 101.10 ? 13  ASP C OD1 1 
ATOM   7298  O OD2 . ASP C 1 5   ? -77.473 29.208  10.520 1.00 116.72 ? 13  ASP C OD2 1 
ATOM   7299  N N   . LEU C 1 6   ? -75.829 31.105  13.927 1.00 128.81 ? 14  LEU C N   1 
ATOM   7300  C CA  . LEU C 1 6   ? -74.798 31.496  14.918 1.00 101.32 ? 14  LEU C CA  1 
ATOM   7301  C C   . LEU C 1 6   ? -75.026 32.947  15.320 1.00 108.38 ? 14  LEU C C   1 
ATOM   7302  O O   . LEU C 1 6   ? -75.141 33.216  16.520 1.00 98.60  ? 14  LEU C O   1 
ATOM   7303  C CB  . LEU C 1 6   ? -73.411 31.341  14.300 1.00 81.34  ? 14  LEU C CB  1 
ATOM   7304  C CG  . LEU C 1 6   ? -72.253 31.584  15.259 1.00 95.21  ? 14  LEU C CG  1 
ATOM   7305  C CD1 . LEU C 1 6   ? -72.191 30.483  16.301 1.00 74.15  ? 14  LEU C CD1 1 
ATOM   7306  C CD2 . LEU C 1 6   ? -70.949 31.657  14.493 1.00 94.32  ? 14  LEU C CD2 1 
ATOM   7307  N N   . TRP C 1 7   ? -75.062 33.850  14.346 1.00 118.34 ? 15  TRP C N   1 
ATOM   7308  C CA  . TRP C 1 7   ? -75.367 35.228  14.712 1.00 140.48 ? 15  TRP C CA  1 
ATOM   7309  C C   . TRP C 1 7   ? -76.501 35.316  15.743 1.00 134.74 ? 15  TRP C C   1 
ATOM   7310  O O   . TRP C 1 7   ? -76.438 36.111  16.695 1.00 132.02 ? 15  TRP C O   1 
ATOM   7311  C CB  . TRP C 1 7   ? -75.647 36.060  13.455 1.00 127.77 ? 15  TRP C CB  1 
ATOM   7312  C CG  . TRP C 1 7   ? -75.434 37.533  13.661 1.00 129.48 ? 15  TRP C CG  1 
ATOM   7313  C CD1 . TRP C 1 7   ? -76.379 38.518  13.626 1.00 123.93 ? 15  TRP C CD1 1 
ATOM   7314  C CD2 . TRP C 1 7   ? -74.170 38.189  13.921 1.00 143.94 ? 15  TRP C CD2 1 
ATOM   7315  N NE1 . TRP C 1 7   ? -75.802 39.736  13.861 1.00 131.50 ? 15  TRP C NE1 1 
ATOM   7316  C CE2 . TRP C 1 7   ? -74.451 39.568  14.035 1.00 139.17 ? 15  TRP C CE2 1 
ATOM   7317  C CE3 . TRP C 1 7   ? -72.842 37.756  14.073 1.00 140.64 ? 15  TRP C CE3 1 
ATOM   7318  C CZ2 . TRP C 1 7   ? -73.441 40.501  14.265 1.00 125.62 ? 15  TRP C CZ2 1 
ATOM   7319  C CZ3 . TRP C 1 7   ? -71.844 38.676  14.319 1.00 98.80  ? 15  TRP C CZ3 1 
ATOM   7320  C CH2 . TRP C 1 7   ? -72.146 40.033  14.384 1.00 113.38 ? 15  TRP C CH2 1 
ATOM   7321  N N   . SER C 1 8   ? -77.520 34.456  15.594 1.00 84.90  ? 16  SER C N   1 
ATOM   7322  C CA  . SER C 1 8   ? -78.599 34.413  16.557 1.00 98.30  ? 16  SER C CA  1 
ATOM   7323  C C   . SER C 1 8   ? -78.119 33.914  17.928 1.00 115.29 ? 16  SER C C   1 
ATOM   7324  O O   . SER C 1 8   ? -78.595 34.400  18.972 1.00 111.17 ? 16  SER C O   1 
ATOM   7325  C CB  . SER C 1 8   ? -79.760 33.653  16.026 1.00 88.62  ? 16  SER C CB  1 
ATOM   7326  O OG  . SER C 1 8   ? -80.908 34.196  16.678 1.00 123.20 ? 16  SER C OG  1 
ATOM   7327  N N   . SER C 1 9   ? -77.141 32.982  17.927 1.00 95.42  ? 17  SER C N   1 
ATOM   7328  C CA  . SER C 1 9   ? -76.648 32.524  19.214 1.00 104.05 ? 17  SER C CA  1 
ATOM   7329  C C   . SER C 1 9   ? -75.674 33.544  19.834 1.00 106.25 ? 17  SER C C   1 
ATOM   7330  O O   . SER C 1 9   ? -75.574 33.684  21.048 1.00 86.91  ? 17  SER C O   1 
ATOM   7331  C CB  . SER C 1 9   ? -76.401 30.993  19.391 1.00 66.01  ? 17  SER C CB  1 
ATOM   7332  O OG  . SER C 1 9   ? -75.033 30.668  19.518 1.00 56.22  ? 17  SER C OG  1 
ATOM   7333  N N   . HIS C 1 10  ? -75.002 34.327  18.996 1.00 86.62  ? 18  HIS C N   1 
ATOM   7334  C CA  . HIS C 1 10  ? -74.223 35.459  19.483 1.00 102.19 ? 18  HIS C CA  1 
ATOM   7335  C C   . HIS C 1 10  ? -75.138 36.458  20.206 1.00 129.41 ? 18  HIS C C   1 
ATOM   7336  O O   . HIS C 1 10  ? -74.799 36.937  21.295 1.00 168.39 ? 18  HIS C O   1 
ATOM   7337  C CB  . HIS C 1 10  ? -73.388 36.072  18.347 1.00 94.86  ? 18  HIS C CB  1 
ATOM   7338  C CG  . HIS C 1 10  ? -72.895 37.471  18.587 1.00 98.55  ? 18  HIS C CG  1 
ATOM   7339  N ND1 . HIS C 1 10  ? -73.642 38.620  18.432 1.00 93.71  ? 18  HIS C ND1 1 
ATOM   7340  C CD2 . HIS C 1 10  ? -71.703 37.888  19.019 1.00 111.00 ? 18  HIS C CD2 1 
ATOM   7341  C CE1 . HIS C 1 10  ? -72.920 39.676  18.779 1.00 100.83 ? 18  HIS C CE1 1 
ATOM   7342  N NE2 . HIS C 1 10  ? -71.722 39.262  19.106 1.00 105.95 ? 18  HIS C NE2 1 
ATOM   7343  N N   . ASP C 1 11  ? -76.272 36.841  19.590 1.00 132.98 ? 19  ASP C N   1 
ATOM   7344  C CA  . ASP C 1 11  ? -77.163 37.798  20.232 1.00 115.38 ? 19  ASP C CA  1 
ATOM   7345  C C   . ASP C 1 11  ? -77.571 37.183  21.565 1.00 120.26 ? 19  ASP C C   1 
ATOM   7346  O O   . ASP C 1 11  ? -77.759 37.903  22.560 1.00 116.47 ? 19  ASP C O   1 
ATOM   7347  C CB  . ASP C 1 11  ? -78.307 38.241  19.328 1.00 135.23 ? 19  ASP C CB  1 
ATOM   7348  C CG  . ASP C 1 11  ? -78.026 39.308  18.269 1.00 152.38 ? 19  ASP C CG  1 
ATOM   7349  O OD1 . ASP C 1 11  ? -77.171 39.075  17.366 1.00 150.54 ? 19  ASP C OD1 1 
ATOM   7350  O OD2 . ASP C 1 11  ? -78.694 40.380  18.327 1.00 119.92 ? 19  ASP C OD2 1 
ATOM   7351  N N   . ALA C 1 12  ? -77.669 35.837  21.552 1.00 86.53  ? 20  ALA C N   1 
ATOM   7352  C CA  . ALA C 1 12  ? -78.138 35.118  22.729 1.00 104.52 ? 20  ALA C CA  1 
ATOM   7353  C C   . ALA C 1 12  ? -77.123 35.256  23.861 1.00 120.09 ? 20  ALA C C   1 
ATOM   7354  O O   . ALA C 1 12  ? -77.481 35.511  25.014 1.00 105.85 ? 20  ALA C O   1 
ATOM   7355  C CB  . ALA C 1 12  ? -78.399 33.677  22.416 1.00 88.06  ? 20  ALA C CB  1 
ATOM   7356  N N   . MET C 1 13  ? -75.839 35.093  23.504 1.00 101.79 ? 21  MET C N   1 
ATOM   7357  C CA  . MET C 1 13  ? -74.721 35.122  24.435 1.00 82.61  ? 21  MET C CA  1 
ATOM   7358  C C   . MET C 1 13  ? -74.874 36.339  25.324 1.00 105.34 ? 21  MET C C   1 
ATOM   7359  O O   . MET C 1 13  ? -74.870 36.220  26.556 1.00 105.65 ? 21  MET C O   1 
ATOM   7360  C CB  . MET C 1 13  ? -73.416 35.378  23.665 1.00 55.90  ? 21  MET C CB  1 
ATOM   7361  C CG  . MET C 1 13  ? -72.174 35.058  24.456 1.00 59.88  ? 21  MET C CG  1 
ATOM   7362  S SD  . MET C 1 13  ? -70.608 34.944  23.532 1.00 84.82  ? 21  MET C SD  1 
ATOM   7363  C CE  . MET C 1 13  ? -71.017 34.637  21.806 1.00 96.79  ? 21  MET C CE  1 
ATOM   7364  N N   . LEU C 1 14  ? -75.034 37.487  24.638 1.00 97.19  ? 22  LEU C N   1 
ATOM   7365  C CA  . LEU C 1 14  ? -75.026 38.803  25.250 1.00 84.25  ? 22  LEU C CA  1 
ATOM   7366  C C   . LEU C 1 14  ? -76.172 38.931  26.235 1.00 123.81 ? 22  LEU C C   1 
ATOM   7367  O O   . LEU C 1 14  ? -76.113 39.800  27.103 1.00 151.14 ? 22  LEU C O   1 
ATOM   7368  C CB  . LEU C 1 14  ? -75.053 39.918  24.221 1.00 67.53  ? 22  LEU C CB  1 
ATOM   7369  C CG  . LEU C 1 14  ? -73.861 39.852  23.262 1.00 121.21 ? 22  LEU C CG  1 
ATOM   7370  C CD1 . LEU C 1 14  ? -73.934 40.751  22.033 1.00 160.59 ? 22  LEU C CD1 1 
ATOM   7371  C CD2 . LEU C 1 14  ? -72.525 39.957  24.003 1.00 123.99 ? 22  LEU C CD2 1 
ATOM   7372  N N   . ALA C 1 15  ? -77.177 38.050  26.120 1.00 128.18 ? 23  ALA C N   1 
ATOM   7373  C CA  . ALA C 1 15  ? -78.366 38.216  26.943 1.00 97.13  ? 23  ALA C CA  1 
ATOM   7374  C C   . ALA C 1 15  ? -78.515 37.096  27.983 1.00 109.61 ? 23  ALA C C   1 
ATOM   7375  O O   . ALA C 1 15  ? -79.332 37.202  28.901 1.00 133.03 ? 23  ALA C O   1 
ATOM   7376  C CB  . ALA C 1 15  ? -79.558 38.343  26.046 1.00 75.27  ? 23  ALA C CB  1 
ATOM   7377  N N   . GLN C 1 16  ? -77.726 36.024  27.853 1.00 89.95  ? 24  GLN C N   1 
ATOM   7378  C CA  . GLN C 1 16  ? -77.887 34.882  28.737 1.00 95.30  ? 24  GLN C CA  1 
ATOM   7379  C C   . GLN C 1 16  ? -77.312 35.178  30.127 1.00 93.18  ? 24  GLN C C   1 
ATOM   7380  O O   . GLN C 1 16  ? -76.242 35.769  30.239 1.00 119.84 ? 24  GLN C O   1 
ATOM   7381  C CB  . GLN C 1 16  ? -77.300 33.726  27.933 1.00 107.91 ? 24  GLN C CB  1 
ATOM   7382  C CG  . GLN C 1 16  ? -77.276 32.369  28.629 1.00 113.57 ? 24  GLN C CG  1 
ATOM   7383  C CD  . GLN C 1 16  ? -76.050 31.592  28.204 1.00 101.69 ? 24  GLN C CD  1 
ATOM   7384  O OE1 . GLN C 1 16  ? -75.219 32.092  27.435 1.00 87.22  ? 24  GLN C OE1 1 
ATOM   7385  N NE2 . GLN C 1 16  ? -75.913 30.380  28.724 1.00 116.41 ? 24  GLN C NE2 1 
ATOM   7386  N N   . PRO C 1 17  ? -77.994 34.751  31.216 1.00 98.52  ? 25  PRO C N   1 
ATOM   7387  C CA  . PRO C 1 17  ? -77.545 34.939  32.596 1.00 122.22 ? 25  PRO C CA  1 
ATOM   7388  C C   . PRO C 1 17  ? -76.168 34.401  32.920 1.00 114.45 ? 25  PRO C C   1 
ATOM   7389  O O   . PRO C 1 17  ? -75.710 33.450  32.281 1.00 105.14 ? 25  PRO C O   1 
ATOM   7390  C CB  . PRO C 1 17  ? -78.586 34.231  33.496 1.00 117.74 ? 25  PRO C CB  1 
ATOM   7391  C CG  . PRO C 1 17  ? -79.763 33.960  32.606 1.00 132.02 ? 25  PRO C CG  1 
ATOM   7392  C CD  . PRO C 1 17  ? -79.304 34.101  31.174 1.00 117.27 ? 25  PRO C CD  1 
ATOM   7393  N N   . LEU C 1 18  ? -75.605 34.967  33.991 1.00 94.46  ? 26  LEU C N   1 
ATOM   7394  C CA  . LEU C 1 18  ? -74.309 34.567  34.506 1.00 81.15  ? 26  LEU C CA  1 
ATOM   7395  C C   . LEU C 1 18  ? -74.377 33.106  34.907 1.00 106.73 ? 26  LEU C C   1 
ATOM   7396  O O   . LEU C 1 18  ? -73.463 32.324  34.626 1.00 144.58 ? 26  LEU C O   1 
ATOM   7397  C CB  . LEU C 1 18  ? -73.839 35.360  35.720 1.00 72.03  ? 26  LEU C CB  1 
ATOM   7398  C CG  . LEU C 1 18  ? -72.409 34.967  36.117 1.00 74.03  ? 26  LEU C CG  1 
ATOM   7399  C CD1 . LEU C 1 18  ? -71.512 35.446  34.986 1.00 79.54  ? 26  LEU C CD1 1 
ATOM   7400  C CD2 . LEU C 1 18  ? -71.851 35.196  37.527 1.00 52.63  ? 26  LEU C CD2 1 
ATOM   7401  N N   . LYS C 1 19  ? -75.469 32.787  35.610 1.00 105.48 ? 27  LYS C N   1 
ATOM   7402  C CA  . LYS C 1 19  ? -75.726 31.451  36.117 1.00 122.92 ? 27  LYS C CA  1 
ATOM   7403  C C   . LYS C 1 19  ? -75.471 30.411  35.031 1.00 132.13 ? 27  LYS C C   1 
ATOM   7404  O O   . LYS C 1 19  ? -74.974 29.339  35.352 1.00 114.45 ? 27  LYS C O   1 
ATOM   7405  C CB  . LYS C 1 19  ? -77.124 31.449  36.753 1.00 134.74 ? 27  LYS C CB  1 
ATOM   7406  C CG  . LYS C 1 19  ? -77.804 30.124  37.088 1.00 160.80 ? 27  LYS C CG  1 
ATOM   7407  C CD  . LYS C 1 19  ? -79.193 30.328  37.719 1.00 142.16 ? 27  LYS C CD  1 
ATOM   7408  C CE  . LYS C 1 19  ? -80.134 31.295  37.037 1.00 95.18  ? 27  LYS C CE  1 
ATOM   7409  N NZ  . LYS C 1 19  ? -80.290 30.952  35.613 1.00 85.70  ? 27  LYS C NZ  1 
ATOM   7410  N N   . ASP C 1 20  ? -75.780 30.744  33.767 1.00 143.17 ? 28  ASP C N   1 
ATOM   7411  C CA  . ASP C 1 20  ? -75.719 29.785  32.676 1.00 109.04 ? 28  ASP C CA  1 
ATOM   7412  C C   . ASP C 1 20  ? -74.426 29.959  31.899 1.00 96.58  ? 28  ASP C C   1 
ATOM   7413  O O   . ASP C 1 20  ? -73.839 28.978  31.473 1.00 118.72 ? 28  ASP C O   1 
ATOM   7414  C CB  . ASP C 1 20  ? -76.905 29.939  31.735 1.00 98.71  ? 28  ASP C CB  1 
ATOM   7415  C CG  . ASP C 1 20  ? -78.289 30.060  32.354 1.00 124.34 ? 28  ASP C CG  1 
ATOM   7416  O OD1 . ASP C 1 20  ? -78.450 30.112  33.620 1.00 128.31 ? 28  ASP C OD1 1 
ATOM   7417  O OD2 . ASP C 1 20  ? -79.214 30.137  31.539 1.00 105.19 ? 28  ASP C OD2 1 
ATOM   7418  N N   . SER C 1 21  ? -74.045 31.211  31.654 1.00 112.87 ? 29  SER C N   1 
ATOM   7419  C CA  . SER C 1 21  ? -72.816 31.528  30.953 1.00 104.28 ? 29  SER C CA  1 
ATOM   7420  C C   . SER C 1 21  ? -71.739 31.746  32.000 1.00 128.73 ? 29  SER C C   1 
ATOM   7421  O O   . SER C 1 21  ? -71.815 32.694  32.779 1.00 159.29 ? 29  SER C O   1 
ATOM   7422  C CB  . SER C 1 21  ? -72.945 32.771  30.153 1.00 80.89  ? 29  SER C CB  1 
ATOM   7423  O OG  . SER C 1 21  ? -71.711 32.943  29.476 1.00 67.99  ? 29  SER C OG  1 
ATOM   7424  N N   . ASP C 1 22  ? -70.761 30.845  32.032 1.00 136.63 ? 30  ASP C N   1 
ATOM   7425  C CA  . ASP C 1 22  ? -69.713 30.902  33.023 1.00 146.42 ? 30  ASP C CA  1 
ATOM   7426  C C   . ASP C 1 22  ? -70.248 30.573  34.409 1.00 131.90 ? 30  ASP C C   1 
ATOM   7427  O O   . ASP C 1 22  ? -70.331 31.435  35.309 1.00 85.46  ? 30  ASP C O   1 
ATOM   7428  C CB  . ASP C 1 22  ? -68.932 32.200  33.015 1.00 149.76 ? 30  ASP C CB  1 
ATOM   7429  C CG  . ASP C 1 22  ? -67.547 31.983  33.587 1.00 150.74 ? 30  ASP C CG  1 
ATOM   7430  O OD1 . ASP C 1 22  ? -67.418 31.193  34.566 1.00 175.49 ? 30  ASP C OD1 1 
ATOM   7431  O OD2 . ASP C 1 22  ? -66.614 32.542  32.984 1.00 141.82 ? 30  ASP C OD2 1 
ATOM   7432  N N   . VAL C 1 23  ? -70.555 29.278  34.569 1.00 106.93 ? 31  VAL C N   1 
ATOM   7433  C CA  . VAL C 1 23  ? -70.952 28.831  35.882 1.00 106.99 ? 31  VAL C CA  1 
ATOM   7434  C C   . VAL C 1 23  ? -69.755 28.771  36.824 1.00 114.09 ? 31  VAL C C   1 
ATOM   7435  O O   . VAL C 1 23  ? -69.960 28.857  38.024 1.00 126.27 ? 31  VAL C O   1 
ATOM   7436  C CB  . VAL C 1 23  ? -71.815 27.578  35.939 1.00 110.55 ? 31  VAL C CB  1 
ATOM   7437  C CG1 . VAL C 1 23  ? -72.443 27.484  37.338 1.00 84.20  ? 31  VAL C CG1 1 
ATOM   7438  C CG2 . VAL C 1 23  ? -72.841 27.625  34.808 1.00 118.57 ? 31  VAL C CG2 1 
ATOM   7439  N N   . GLU C 1 24  ? -68.521 28.687  36.324 1.00 110.46 ? 32  GLU C N   1 
ATOM   7440  C CA  . GLU C 1 24  ? -67.342 28.686  37.195 1.00 98.34  ? 32  GLU C CA  1 
ATOM   7441  C C   . GLU C 1 24  ? -67.350 29.957  38.041 1.00 102.24 ? 32  GLU C C   1 
ATOM   7442  O O   . GLU C 1 24  ? -67.284 29.889  39.266 1.00 134.28 ? 32  GLU C O   1 
ATOM   7443  C CB  . GLU C 1 24  ? -66.007 28.519  36.460 1.00 74.88  ? 32  GLU C CB  1 
ATOM   7444  C CG  . GLU C 1 24  ? -66.218 27.803  35.120 1.00 83.03  ? 32  GLU C CG  1 
ATOM   7445  C CD  . GLU C 1 24  ? -65.303 28.262  34.021 1.00 117.15 ? 32  GLU C CD  1 
ATOM   7446  O OE1 . GLU C 1 24  ? -65.712 28.153  32.848 1.00 110.07 ? 32  GLU C OE1 1 
ATOM   7447  O OE2 . GLU C 1 24  ? -64.211 28.738  34.402 1.00 161.96 ? 32  GLU C OE2 1 
ATOM   7448  N N   . VAL C 1 25  ? -67.459 31.114  37.375 1.00 74.65  ? 33  VAL C N   1 
ATOM   7449  C CA  . VAL C 1 25  ? -67.511 32.390  38.063 1.00 74.49  ? 33  VAL C CA  1 
ATOM   7450  C C   . VAL C 1 25  ? -68.707 32.420  39.030 1.00 86.61  ? 33  VAL C C   1 
ATOM   7451  O O   . VAL C 1 25  ? -68.549 32.833  40.188 1.00 51.05  ? 33  VAL C O   1 
ATOM   7452  C CB  . VAL C 1 25  ? -67.666 33.543  37.049 1.00 67.04  ? 33  VAL C CB  1 
ATOM   7453  C CG1 . VAL C 1 25  ? -67.967 34.859  37.785 1.00 55.51  ? 33  VAL C CG1 1 
ATOM   7454  C CG2 . VAL C 1 25  ? -66.515 33.684  36.066 1.00 56.01  ? 33  VAL C CG2 1 
ATOM   7455  N N   . TYR C 1 26  ? -69.879 31.999  38.515 1.00 90.84  ? 34  TYR C N   1 
ATOM   7456  C CA  . TYR C 1 26  ? -71.127 31.988  39.250 1.00 92.26  ? 34  TYR C CA  1 
ATOM   7457  C C   . TYR C 1 26  ? -70.916 31.264  40.578 1.00 102.69 ? 34  TYR C C   1 
ATOM   7458  O O   . TYR C 1 26  ? -71.325 31.758  41.646 1.00 78.82  ? 34  TYR C O   1 
ATOM   7459  C CB  . TYR C 1 26  ? -72.253 31.404  38.391 1.00 91.19  ? 34  TYR C CB  1 
ATOM   7460  C CG  . TYR C 1 26  ? -73.582 31.306  39.124 1.00 116.85 ? 34  TYR C CG  1 
ATOM   7461  C CD1 . TYR C 1 26  ? -74.468 32.382  39.156 1.00 121.37 ? 34  TYR C CD1 1 
ATOM   7462  C CD2 . TYR C 1 26  ? -73.930 30.157  39.824 1.00 116.23 ? 34  TYR C CD2 1 
ATOM   7463  C CE1 . TYR C 1 26  ? -75.651 32.324  39.878 1.00 142.22 ? 34  TYR C CE1 1 
ATOM   7464  C CE2 . TYR C 1 26  ? -75.133 30.074  40.513 1.00 120.99 ? 34  TYR C CE2 1 
ATOM   7465  C CZ  . TYR C 1 26  ? -76.010 31.145  40.506 1.00 144.47 ? 34  TYR C CZ  1 
ATOM   7466  O OH  . TYR C 1 26  ? -77.180 31.074  41.207 1.00 157.80 ? 34  TYR C OH  1 
ATOM   7467  N N   . ASN C 1 27  ? -70.247 30.103  40.523 1.00 101.65 ? 35  ASN C N   1 
ATOM   7468  C CA  . ASN C 1 27  ? -70.012 29.326  41.739 1.00 122.29 ? 35  ASN C CA  1 
ATOM   7469  C C   . ASN C 1 27  ? -69.119 30.128  42.677 1.00 119.23 ? 35  ASN C C   1 
ATOM   7470  O O   . ASN C 1 27  ? -69.417 30.210  43.872 1.00 82.61  ? 35  ASN C O   1 
ATOM   7471  C CB  . ASN C 1 27  ? -69.274 27.992  41.595 1.00 95.12  ? 35  ASN C CB  1 
ATOM   7472  C CG  . ASN C 1 27  ? -69.749 27.124  40.458 1.00 99.58  ? 35  ASN C CG  1 
ATOM   7473  O OD1 . ASN C 1 27  ? -70.965 26.962  40.265 1.00 106.47 ? 35  ASN C OD1 1 
ATOM   7474  N ND2 . ASN C 1 27  ? -68.790 26.648  39.665 1.00 79.19  ? 35  ASN C ND2 1 
ATOM   7475  N N   . ILE C 1 28  ? -68.029 30.692  42.131 1.00 110.33 ? 36  ILE C N   1 
ATOM   7476  C CA  . ILE C 1 28  ? -67.112 31.468  42.943 1.00 99.04  ? 36  ILE C CA  1 
ATOM   7477  C C   . ILE C 1 28  ? -67.919 32.517  43.714 1.00 92.61  ? 36  ILE C C   1 
ATOM   7478  O O   . ILE C 1 28  ? -67.835 32.612  44.940 1.00 66.05  ? 36  ILE C O   1 
ATOM   7479  C CB  . ILE C 1 28  ? -66.000 32.093  42.088 1.00 81.15  ? 36  ILE C CB  1 
ATOM   7480  C CG1 . ILE C 1 28  ? -65.107 31.028  41.478 1.00 83.27  ? 36  ILE C CG1 1 
ATOM   7481  C CG2 . ILE C 1 28  ? -65.193 33.094  42.925 1.00 65.57  ? 36  ILE C CG2 1 
ATOM   7482  C CD1 . ILE C 1 28  ? -63.845 31.595  40.853 1.00 91.72  ? 36  ILE C CD1 1 
ATOM   7483  N N   . ILE C 1 29  ? -68.721 33.295  42.985 1.00 74.27  ? 37  ILE C N   1 
ATOM   7484  C CA  . ILE C 1 29  ? -69.528 34.308  43.642 1.00 87.99  ? 37  ILE C CA  1 
ATOM   7485  C C   . ILE C 1 29  ? -70.420 33.691  44.720 1.00 102.34 ? 37  ILE C C   1 
ATOM   7486  O O   . ILE C 1 29  ? -70.473 34.215  45.851 1.00 77.47  ? 37  ILE C O   1 
ATOM   7487  C CB  . ILE C 1 29  ? -70.325 35.174  42.658 1.00 81.22  ? 37  ILE C CB  1 
ATOM   7488  C CG1 . ILE C 1 29  ? -69.415 35.755  41.592 1.00 91.89  ? 37  ILE C CG1 1 
ATOM   7489  C CG2 . ILE C 1 29  ? -71.009 36.306  43.441 1.00 64.78  ? 37  ILE C CG2 1 
ATOM   7490  C CD1 . ILE C 1 29  ? -70.157 36.531  40.522 1.00 106.35 ? 37  ILE C CD1 1 
ATOM   7491  N N   . LYS C 1 30  ? -71.129 32.601  44.371 1.00 97.84  ? 38  LYS C N   1 
ATOM   7492  C CA  . LYS C 1 30  ? -72.011 31.919  45.328 1.00 105.59 ? 38  LYS C CA  1 
ATOM   7493  C C   . LYS C 1 30  ? -71.206 31.436  46.540 1.00 110.15 ? 38  LYS C C   1 
ATOM   7494  O O   . LYS C 1 30  ? -71.584 31.713  47.700 1.00 112.37 ? 38  LYS C O   1 
ATOM   7495  C CB  . LYS C 1 30  ? -72.839 30.722  44.821 1.00 94.01  ? 38  LYS C CB  1 
ATOM   7496  C CG  . LYS C 1 30  ? -74.252 30.845  44.234 1.00 136.24 ? 38  LYS C CG  1 
ATOM   7497  C CD  . LYS C 1 30  ? -75.010 29.631  43.646 1.00 119.02 ? 38  LYS C CD  1 
ATOM   7498  C CE  . LYS C 1 30  ? -75.219 28.214  44.242 1.00 99.77  ? 38  LYS C CE  1 
ATOM   7499  N NZ  . LYS C 1 30  ? -75.454 28.069  45.694 1.00 90.81  ? 38  LYS C NZ  1 
ATOM   7500  N N   . LYS C 1 31  ? -70.088 30.720  46.261 1.00 83.84  ? 39  LYS C N   1 
ATOM   7501  C CA  . LYS C 1 31  ? -69.257 30.201  47.334 1.00 71.47  ? 39  LYS C CA  1 
ATOM   7502  C C   . LYS C 1 31  ? -68.811 31.348  48.242 1.00 70.91  ? 39  LYS C C   1 
ATOM   7503  O O   . LYS C 1 31  ? -68.790 31.193  49.461 1.00 63.74  ? 39  LYS C O   1 
ATOM   7504  C CB  . LYS C 1 31  ? -67.988 29.430  46.932 1.00 60.47  ? 39  LYS C CB  1 
ATOM   7505  C CG  . LYS C 1 31  ? -67.987 28.176  46.111 1.00 74.24  ? 39  LYS C CG  1 
ATOM   7506  C CD  . LYS C 1 31  ? -66.501 27.949  45.823 1.00 86.17  ? 39  LYS C CD  1 
ATOM   7507  C CE  . LYS C 1 31  ? -66.003 26.729  45.128 1.00 90.11  ? 39  LYS C CE  1 
ATOM   7508  N NZ  . LYS C 1 31  ? -64.554 26.542  45.320 1.00 70.59  ? 39  LYS C NZ  1 
ATOM   7509  N N   . GLU C 1 32  ? -68.449 32.493  47.647 1.00 79.35  ? 40  GLU C N   1 
ATOM   7510  C CA  . GLU C 1 32  ? -67.895 33.616  48.383 1.00 102.82 ? 40  GLU C CA  1 
ATOM   7511  C C   . GLU C 1 32  ? -68.991 34.236  49.240 1.00 114.32 ? 40  GLU C C   1 
ATOM   7512  O O   . GLU C 1 32  ? -68.744 34.637  50.392 1.00 91.34  ? 40  GLU C O   1 
ATOM   7513  C CB  . GLU C 1 32  ? -67.335 34.635  47.386 1.00 86.75  ? 40  GLU C CB  1 
ATOM   7514  C CG  . GLU C 1 32  ? -66.897 35.941  48.040 1.00 80.54  ? 40  GLU C CG  1 
ATOM   7515  C CD  . GLU C 1 32  ? -65.787 35.770  49.078 1.00 102.93 ? 40  GLU C CD  1 
ATOM   7516  O OE1 . GLU C 1 32  ? -65.104 34.714  49.227 1.00 125.70 ? 40  GLU C OE1 1 
ATOM   7517  O OE2 . GLU C 1 32  ? -65.604 36.782  49.775 1.00 74.67  ? 40  GLU C OE2 1 
ATOM   7518  N N   . SER C 1 33  ? -70.202 34.307  48.651 1.00 88.29  ? 41  SER C N   1 
ATOM   7519  C CA  . SER C 1 33  ? -71.339 34.834  49.378 1.00 104.56 ? 41  SER C CA  1 
ATOM   7520  C C   . SER C 1 33  ? -71.582 34.022  50.646 1.00 118.90 ? 41  SER C C   1 
ATOM   7521  O O   . SER C 1 33  ? -71.885 34.577  51.721 1.00 92.60  ? 41  SER C O   1 
ATOM   7522  C CB  . SER C 1 33  ? -72.553 34.849  48.527 1.00 83.91  ? 41  SER C CB  1 
ATOM   7523  O OG  . SER C 1 33  ? -73.586 35.427  49.315 1.00 84.39  ? 41  SER C OG  1 
ATOM   7524  N N   . ASN C 1 34  ? -71.452 32.698  50.484 1.00 112.34 ? 42  ASN C N   1 
ATOM   7525  C CA  . ASN C 1 34  ? -71.678 31.801  51.598 1.00 112.88 ? 42  ASN C CA  1 
ATOM   7526  C C   . ASN C 1 34  ? -70.567 32.007  52.634 1.00 110.65 ? 42  ASN C C   1 
ATOM   7527  O O   . ASN C 1 34  ? -70.824 32.040  53.847 1.00 103.74 ? 42  ASN C O   1 
ATOM   7528  C CB  . ASN C 1 34  ? -71.899 30.365  51.139 1.00 78.82  ? 42  ASN C CB  1 
ATOM   7529  C CG  . ASN C 1 34  ? -72.079 29.496  52.359 1.00 106.08 ? 42  ASN C CG  1 
ATOM   7530  O OD1 . ASN C 1 34  ? -73.087 29.622  53.068 1.00 133.72 ? 42  ASN C OD1 1 
ATOM   7531  N ND2 . ASN C 1 34  ? -71.107 28.642  52.656 1.00 99.33  ? 42  ASN C ND2 1 
ATOM   7532  N N   . ARG C 1 35  ? -69.332 32.144  52.131 1.00 77.32  ? 43  ARG C N   1 
ATOM   7533  C CA  . ARG C 1 35  ? -68.174 32.334  52.990 1.00 85.19  ? 43  ARG C CA  1 
ATOM   7534  C C   . ARG C 1 35  ? -68.414 33.569  53.856 1.00 93.54  ? 43  ARG C C   1 
ATOM   7535  O O   . ARG C 1 35  ? -68.127 33.530  55.055 1.00 93.91  ? 43  ARG C O   1 
ATOM   7536  C CB  . ARG C 1 35  ? -66.830 32.361  52.237 1.00 87.68  ? 43  ARG C CB  1 
ATOM   7537  C CG  . ARG C 1 35  ? -65.733 32.928  53.140 1.00 75.88  ? 43  ARG C CG  1 
ATOM   7538  C CD  . ARG C 1 35  ? -64.676 33.665  52.320 1.00 81.84  ? 43  ARG C CD  1 
ATOM   7539  N NE  . ARG C 1 35  ? -64.090 34.768  53.089 1.00 89.75  ? 43  ARG C NE  1 
ATOM   7540  C CZ  . ARG C 1 35  ? -64.413 36.064  52.999 1.00 115.45 ? 43  ARG C CZ  1 
ATOM   7541  N NH1 . ARG C 1 35  ? -65.462 36.385  52.301 1.00 128.16 ? 43  ARG C NH1 1 
ATOM   7542  N NH2 . ARG C 1 35  ? -63.791 37.043  53.655 1.00 153.45 ? 43  ARG C NH2 1 
ATOM   7543  N N   . GLN C 1 36  ? -68.914 34.653  53.227 1.00 74.72  ? 44  GLN C N   1 
ATOM   7544  C CA  . GLN C 1 36  ? -69.127 35.937  53.897 1.00 88.18  ? 44  GLN C CA  1 
ATOM   7545  C C   . GLN C 1 36  ? -70.157 35.726  54.994 1.00 84.72  ? 44  GLN C C   1 
ATOM   7546  O O   . GLN C 1 36  ? -69.967 36.244  56.096 1.00 85.59  ? 44  GLN C O   1 
ATOM   7547  C CB  . GLN C 1 36  ? -69.461 37.156  53.021 1.00 84.35  ? 44  GLN C CB  1 
ATOM   7548  C CG  . GLN C 1 36  ? -68.314 37.627  52.129 1.00 98.42  ? 44  GLN C CG  1 
ATOM   7549  C CD  . GLN C 1 36  ? -68.674 38.539  50.980 1.00 101.63 ? 44  GLN C CD  1 
ATOM   7550  O OE1 . GLN C 1 36  ? -69.397 39.519  51.154 1.00 123.61 ? 44  GLN C OE1 1 
ATOM   7551  N NE2 . GLN C 1 36  ? -68.116 38.274  49.803 1.00 88.49  ? 44  GLN C NE2 1 
ATOM   7552  N N   . ARG C 1 37  ? -71.157 34.877  54.701 1.00 73.41  ? 45  ARG C N   1 
ATOM   7553  C CA  . ARG C 1 37  ? -72.317 34.681  55.565 1.00 80.86  ? 45  ARG C CA  1 
ATOM   7554  C C   . ARG C 1 37  ? -71.924 33.959  56.862 1.00 103.90 ? 45  ARG C C   1 
ATOM   7555  O O   . ARG C 1 37  ? -72.364 34.334  57.946 1.00 95.88  ? 45  ARG C O   1 
ATOM   7556  C CB  . ARG C 1 37  ? -73.409 33.898  54.829 1.00 104.52 ? 45  ARG C CB  1 
ATOM   7557  C CG  . ARG C 1 37  ? -74.786 34.074  55.460 1.00 117.25 ? 45  ARG C CG  1 
ATOM   7558  C CD  . ARG C 1 37  ? -76.023 33.795  54.552 1.00 80.60  ? 45  ARG C CD  1 
ATOM   7559  N NE  . ARG C 1 37  ? -75.958 32.340  54.390 1.00 90.19  ? 45  ARG C NE  1 
ATOM   7560  C CZ  . ARG C 1 37  ? -75.902 31.423  55.393 1.00 132.35 ? 45  ARG C CZ  1 
ATOM   7561  N NH1 . ARG C 1 37  ? -75.474 30.188  55.137 1.00 151.33 ? 45  ARG C NH1 1 
ATOM   7562  N NH2 . ARG C 1 37  ? -76.159 31.764  56.668 1.00 101.42 ? 45  ARG C NH2 1 
ATOM   7563  N N   . VAL C 1 38  ? -71.088 32.919  56.766 1.00 90.01  ? 46  VAL C N   1 
ATOM   7564  C CA  . VAL C 1 38  ? -70.751 32.119  57.936 1.00 87.94  ? 46  VAL C CA  1 
ATOM   7565  C C   . VAL C 1 38  ? -69.562 32.671  58.722 1.00 91.32  ? 46  VAL C C   1 
ATOM   7566  O O   . VAL C 1 38  ? -69.290 32.186  59.815 1.00 131.29 ? 46  VAL C O   1 
ATOM   7567  C CB  . VAL C 1 38  ? -70.476 30.666  57.537 1.00 99.79  ? 46  VAL C CB  1 
ATOM   7568  C CG1 . VAL C 1 38  ? -71.664 30.109  56.750 1.00 104.61 ? 46  VAL C CG1 1 
ATOM   7569  C CG2 . VAL C 1 38  ? -69.156 30.587  56.776 1.00 129.14 ? 46  VAL C CG2 1 
ATOM   7570  N N   . GLY C 1 39  ? -68.837 33.660  58.187 1.00 70.72  ? 47  GLY C N   1 
ATOM   7571  C CA  . GLY C 1 39  ? -67.663 34.198  58.875 1.00 72.57  ? 47  GLY C CA  1 
ATOM   7572  C C   . GLY C 1 39  ? -68.000 35.422  59.738 1.00 91.02  ? 47  GLY C C   1 
ATOM   7573  O O   . GLY C 1 39  ? -68.993 36.141  59.512 1.00 87.48  ? 47  GLY C O   1 
ATOM   7574  N N   . LEU C 1 40  ? -67.154 35.667  60.742 1.00 94.03  ? 48  LEU C N   1 
ATOM   7575  C CA  . LEU C 1 40  ? -67.230 36.902  61.507 1.00 92.54  ? 48  LEU C CA  1 
ATOM   7576  C C   . LEU C 1 40  ? -66.192 37.876  60.951 1.00 109.60 ? 48  LEU C C   1 
ATOM   7577  O O   . LEU C 1 40  ? -64.977 37.738  61.231 1.00 97.10  ? 48  LEU C O   1 
ATOM   7578  C CB  . LEU C 1 40  ? -66.921 36.614  62.971 1.00 91.94  ? 48  LEU C CB  1 
ATOM   7579  C CG  . LEU C 1 40  ? -67.922 35.790  63.772 1.00 81.42  ? 48  LEU C CG  1 
ATOM   7580  C CD1 . LEU C 1 40  ? -67.327 35.708  65.158 1.00 83.19  ? 48  LEU C CD1 1 
ATOM   7581  C CD2 . LEU C 1 40  ? -69.128 36.651  63.863 1.00 82.75  ? 48  LEU C CD2 1 
ATOM   7582  N N   . GLU C 1 41  ? -66.688 38.883  60.188 1.00 84.53  ? 49  GLU C N   1 
ATOM   7583  C CA  . GLU C 1 41  ? -65.787 39.866  59.593 1.00 86.75  ? 49  GLU C CA  1 
ATOM   7584  C C   . GLU C 1 41  ? -65.492 41.028  60.570 1.00 114.27 ? 49  GLU C C   1 
ATOM   7585  O O   . GLU C 1 41  ? -66.335 41.911  60.821 1.00 144.36 ? 49  GLU C O   1 
ATOM   7586  C CB  . GLU C 1 41  ? -66.284 40.326  58.238 1.00 73.30  ? 49  GLU C CB  1 
ATOM   7587  C CG  . GLU C 1 41  ? -65.118 40.843  57.404 1.00 112.45 ? 49  GLU C CG  1 
ATOM   7588  C CD  . GLU C 1 41  ? -64.779 39.870  56.293 1.00 136.29 ? 49  GLU C CD  1 
ATOM   7589  O OE1 . GLU C 1 41  ? -65.804 39.370  55.802 1.00 135.87 ? 49  GLU C OE1 1 
ATOM   7590  O OE2 . GLU C 1 41  ? -63.628 39.656  55.856 1.00 147.80 ? 49  GLU C OE2 1 
ATOM   7591  N N   . LEU C 1 42  ? -64.254 41.050  61.093 1.00 107.71 ? 50  LEU C N   1 
ATOM   7592  C CA  . LEU C 1 42  ? -63.791 42.165  61.904 1.00 102.95 ? 50  LEU C CA  1 
ATOM   7593  C C   . LEU C 1 42  ? -62.623 42.921  61.255 1.00 119.47 ? 50  LEU C C   1 
ATOM   7594  O O   . LEU C 1 42  ? -61.926 43.716  61.925 1.00 67.76  ? 50  LEU C O   1 
ATOM   7595  C CB  . LEU C 1 42  ? -63.362 41.709  63.285 1.00 98.49  ? 50  LEU C CB  1 
ATOM   7596  C CG  . LEU C 1 42  ? -64.499 41.380  64.237 1.00 107.66 ? 50  LEU C CG  1 
ATOM   7597  C CD1 . LEU C 1 42  ? -64.370 39.887  64.424 1.00 121.23 ? 50  LEU C CD1 1 
ATOM   7598  C CD2 . LEU C 1 42  ? -64.264 42.140  65.544 1.00 116.74 ? 50  LEU C CD2 1 
ATOM   7599  N N   . ILE C 1 43  ? -62.396 42.688  59.948 1.00 96.29  ? 51  ILE C N   1 
ATOM   7600  C CA  . ILE C 1 43  ? -61.502 43.576  59.225 1.00 88.55  ? 51  ILE C CA  1 
ATOM   7601  C C   . ILE C 1 43  ? -62.125 44.974  59.105 1.00 98.20  ? 51  ILE C C   1 
ATOM   7602  O O   . ILE C 1 43  ? -63.131 45.193  58.413 1.00 67.32  ? 51  ILE C O   1 
ATOM   7603  C CB  . ILE C 1 43  ? -61.211 42.982  57.853 1.00 94.76  ? 51  ILE C CB  1 
ATOM   7604  C CG1 . ILE C 1 43  ? -60.608 41.602  57.956 1.00 103.56 ? 51  ILE C CG1 1 
ATOM   7605  C CG2 . ILE C 1 43  ? -60.311 43.941  57.082 1.00 125.82 ? 51  ILE C CG2 1 
ATOM   7606  C CD1 . ILE C 1 43  ? -60.489 40.947  56.588 1.00 153.87 ? 51  ILE C CD1 1 
ATOM   7607  N N   . ALA C 1 44  ? -61.483 45.951  59.754 1.00 91.77  ? 52  ALA C N   1 
ATOM   7608  C CA  . ALA C 1 44  ? -62.044 47.294  59.868 1.00 86.06  ? 52  ALA C CA  1 
ATOM   7609  C C   . ALA C 1 44  ? -62.349 47.988  58.511 1.00 94.81  ? 52  ALA C C   1 
ATOM   7610  O O   . ALA C 1 44  ? -63.121 48.956  58.449 1.00 77.63  ? 52  ALA C O   1 
ATOM   7611  C CB  . ALA C 1 44  ? -61.075 48.102  60.700 1.00 86.72  ? 52  ALA C CB  1 
ATOM   7612  N N   . SER C 1 45  ? -61.739 47.541  57.400 1.00 91.50  ? 53  SER C N   1 
ATOM   7613  C CA  . SER C 1 45  ? -61.921 48.196  56.110 1.00 91.71  ? 53  SER C CA  1 
ATOM   7614  C C   . SER C 1 45  ? -63.048 47.563  55.292 1.00 127.27 ? 53  SER C C   1 
ATOM   7615  O O   . SER C 1 45  ? -63.414 48.077  54.223 1.00 149.29 ? 53  SER C O   1 
ATOM   7616  C CB  . SER C 1 45  ? -60.631 48.246  55.327 1.00 103.14 ? 53  SER C CB  1 
ATOM   7617  O OG  . SER C 1 45  ? -60.070 46.959  55.162 1.00 116.62 ? 53  SER C OG  1 
ATOM   7618  N N   . GLU C 1 46  ? -63.630 46.481  55.836 1.00 125.92 ? 54  GLU C N   1 
ATOM   7619  C CA  . GLU C 1 46  ? -64.712 45.778  55.168 1.00 116.75 ? 54  GLU C CA  1 
ATOM   7620  C C   . GLU C 1 46  ? -66.058 46.291  55.670 1.00 120.34 ? 54  GLU C C   1 
ATOM   7621  O O   . GLU C 1 46  ? -66.207 46.834  56.775 1.00 127.26 ? 54  GLU C O   1 
ATOM   7622  C CB  . GLU C 1 46  ? -64.565 44.275  55.373 1.00 92.13  ? 54  GLU C CB  1 
ATOM   7623  C CG  . GLU C 1 46  ? -63.295 43.714  54.745 1.00 110.57 ? 54  GLU C CG  1 
ATOM   7624  C CD  . GLU C 1 46  ? -63.397 42.809  53.521 1.00 119.92 ? 54  GLU C CD  1 
ATOM   7625  O OE1 . GLU C 1 46  ? -64.499 42.553  52.983 1.00 119.29 ? 54  GLU C OE1 1 
ATOM   7626  O OE2 . GLU C 1 46  ? -62.323 42.281  53.161 1.00 103.98 ? 54  GLU C OE2 1 
ATOM   7627  N N   . ASN C 1 47  ? -67.044 46.104  54.795 1.00 109.88 ? 55  ASN C N   1 
ATOM   7628  C CA  . ASN C 1 47  ? -68.452 46.295  55.096 1.00 86.48  ? 55  ASN C CA  1 
ATOM   7629  C C   . ASN C 1 47  ? -69.231 45.501  54.057 1.00 98.38  ? 55  ASN C C   1 
ATOM   7630  O O   . ASN C 1 47  ? -68.615 44.911  53.163 1.00 115.42 ? 55  ASN C O   1 
ATOM   7631  C CB  . ASN C 1 47  ? -68.838 47.765  55.053 1.00 78.01  ? 55  ASN C CB  1 
ATOM   7632  C CG  . ASN C 1 47  ? -69.843 48.161  56.088 1.00 80.16  ? 55  ASN C CG  1 
ATOM   7633  O OD1 . ASN C 1 47  ? -70.806 47.427  56.337 1.00 91.15  ? 55  ASN C OD1 1 
ATOM   7634  N ND2 . ASN C 1 47  ? -69.602 49.289  56.733 1.00 85.41  ? 55  ASN C ND2 1 
ATOM   7635  N N   . PHE C 1 48  ? -70.567 45.484  54.196 1.00 91.73  ? 56  PHE C N   1 
ATOM   7636  C CA  . PHE C 1 48  ? -71.416 44.821  53.214 1.00 93.03  ? 56  PHE C CA  1 
ATOM   7637  C C   . PHE C 1 48  ? -72.280 45.887  52.559 1.00 107.98 ? 56  PHE C C   1 
ATOM   7638  O O   . PHE C 1 48  ? -73.054 46.559  53.243 1.00 82.16  ? 56  PHE C O   1 
ATOM   7639  C CB  . PHE C 1 48  ? -72.246 43.642  53.731 1.00 64.89  ? 56  PHE C CB  1 
ATOM   7640  C CG  . PHE C 1 48  ? -71.376 42.657  54.493 1.00 69.72  ? 56  PHE C CG  1 
ATOM   7641  C CD1 . PHE C 1 48  ? -70.501 41.819  53.788 1.00 69.34  ? 56  PHE C CD1 1 
ATOM   7642  C CD2 . PHE C 1 48  ? -71.367 42.629  55.895 1.00 53.83  ? 56  PHE C CD2 1 
ATOM   7643  C CE1 . PHE C 1 48  ? -69.681 40.910  54.464 1.00 86.40  ? 56  PHE C CE1 1 
ATOM   7644  C CE2 . PHE C 1 48  ? -70.575 41.698  56.563 1.00 53.73  ? 56  PHE C CE2 1 
ATOM   7645  C CZ  . PHE C 1 48  ? -69.711 40.869  55.844 1.00 88.59  ? 56  PHE C CZ  1 
ATOM   7646  N N   . ALA C 1 49  ? -72.122 46.016  51.233 1.00 126.20 ? 57  ALA C N   1 
ATOM   7647  C CA  . ALA C 1 49  ? -72.875 46.965  50.442 1.00 115.90 ? 57  ALA C CA  1 
ATOM   7648  C C   . ALA C 1 49  ? -74.311 46.470  50.329 1.00 105.66 ? 57  ALA C C   1 
ATOM   7649  O O   . ALA C 1 49  ? -74.548 45.265  50.185 1.00 90.27  ? 57  ALA C O   1 
ATOM   7650  C CB  . ALA C 1 49  ? -72.237 47.112  49.082 1.00 122.45 ? 57  ALA C CB  1 
ATOM   7651  N N   . SER C 1 50  ? -75.248 47.434  50.410 1.00 96.18  ? 58  SER C N   1 
ATOM   7652  C CA  . SER C 1 50  ? -76.679 47.161  50.374 1.00 96.98  ? 58  SER C CA  1 
ATOM   7653  C C   . SER C 1 50  ? -77.104 46.645  48.997 1.00 84.36  ? 58  SER C C   1 
ATOM   7654  O O   . SER C 1 50  ? -76.412 46.861  48.000 1.00 115.33 ? 58  SER C O   1 
ATOM   7655  C CB  . SER C 1 50  ? -77.418 48.390  50.748 1.00 101.60 ? 58  SER C CB  1 
ATOM   7656  O OG  . SER C 1 50  ? -77.137 49.393  49.784 1.00 83.69  ? 58  SER C OG  1 
ATOM   7657  N N   . ARG C 1 51  ? -78.234 45.936  48.923 1.00 81.89  ? 59  ARG C N   1 
ATOM   7658  C CA  . ARG C 1 51  ? -78.609 45.366  47.629 1.00 95.27  ? 59  ARG C CA  1 
ATOM   7659  C C   . ARG C 1 51  ? -78.910 46.510  46.664 1.00 105.64 ? 59  ARG C C   1 
ATOM   7660  O O   . ARG C 1 51  ? -78.610 46.401  45.454 1.00 64.60  ? 59  ARG C O   1 
ATOM   7661  C CB  . ARG C 1 51  ? -79.795 44.408  47.645 1.00 76.21  ? 59  ARG C CB  1 
ATOM   7662  C CG  . ARG C 1 51  ? -79.773 43.377  46.543 1.00 61.96  ? 59  ARG C CG  1 
ATOM   7663  C CD  . ARG C 1 51  ? -81.155 42.694  46.542 1.00 100.24 ? 59  ARG C CD  1 
ATOM   7664  N NE  . ARG C 1 51  ? -81.986 43.134  45.414 1.00 127.65 ? 59  ARG C NE  1 
ATOM   7665  C CZ  . ARG C 1 51  ? -83.209 43.667  45.431 1.00 123.08 ? 59  ARG C CZ  1 
ATOM   7666  N NH1 . ARG C 1 51  ? -83.822 43.941  44.309 1.00 141.77 ? 59  ARG C NH1 1 
ATOM   7667  N NH2 . ARG C 1 51  ? -83.812 43.893  46.579 1.00 86.10  ? 59  ARG C NH2 1 
ATOM   7668  N N   . ALA C 1 52  ? -79.450 47.602  47.245 1.00 95.24  ? 60  ALA C N   1 
ATOM   7669  C CA  . ALA C 1 52  ? -79.749 48.762  46.421 1.00 120.63 ? 60  ALA C CA  1 
ATOM   7670  C C   . ALA C 1 52  ? -78.501 49.159  45.609 1.00 105.09 ? 60  ALA C C   1 
ATOM   7671  O O   . ALA C 1 52  ? -78.564 49.329  44.398 1.00 85.46  ? 60  ALA C O   1 
ATOM   7672  C CB  . ALA C 1 52  ? -80.335 49.870  47.289 1.00 103.09 ? 60  ALA C CB  1 
ATOM   7673  N N   . VAL C 1 53  ? -77.358 49.281  46.291 1.00 100.25 ? 61  VAL C N   1 
ATOM   7674  C CA  . VAL C 1 53  ? -76.090 49.713  45.713 1.00 82.42  ? 61  VAL C CA  1 
ATOM   7675  C C   . VAL C 1 53  ? -75.621 48.723  44.665 1.00 83.25  ? 61  VAL C C   1 
ATOM   7676  O O   . VAL C 1 53  ? -75.234 49.100  43.569 1.00 86.72  ? 61  VAL C O   1 
ATOM   7677  C CB  . VAL C 1 53  ? -75.006 49.884  46.784 1.00 81.68  ? 61  VAL C CB  1 
ATOM   7678  C CG1 . VAL C 1 53  ? -73.627 50.108  46.147 1.00 78.38  ? 61  VAL C CG1 1 
ATOM   7679  C CG2 . VAL C 1 53  ? -75.412 51.009  47.741 1.00 77.23  ? 61  VAL C CG2 1 
ATOM   7680  N N   . LEU C 1 54  ? -75.626 47.442  45.004 1.00 79.26  ? 62  LEU C N   1 
ATOM   7681  C CA  . LEU C 1 54  ? -75.270 46.425  44.027 1.00 91.00  ? 62  LEU C CA  1 
ATOM   7682  C C   . LEU C 1 54  ? -76.181 46.526  42.794 1.00 93.61  ? 62  LEU C C   1 
ATOM   7683  O O   . LEU C 1 54  ? -75.712 46.319  41.667 1.00 64.46  ? 62  LEU C O   1 
ATOM   7684  C CB  . LEU C 1 54  ? -75.267 45.041  44.667 1.00 81.17  ? 62  LEU C CB  1 
ATOM   7685  C CG  . LEU C 1 54  ? -74.355 44.893  45.888 1.00 84.34  ? 62  LEU C CG  1 
ATOM   7686  C CD1 . LEU C 1 54  ? -74.605 43.525  46.480 1.00 84.85  ? 62  LEU C CD1 1 
ATOM   7687  C CD2 . LEU C 1 54  ? -72.854 45.046  45.645 1.00 87.67  ? 62  LEU C CD2 1 
ATOM   7688  N N   . GLU C 1 55  ? -77.469 46.850  43.004 1.00 63.54  ? 63  GLU C N   1 
ATOM   7689  C CA  . GLU C 1 55  ? -78.346 47.022  41.853 1.00 87.32  ? 63  GLU C CA  1 
ATOM   7690  C C   . GLU C 1 55  ? -77.847 48.141  40.921 1.00 75.62  ? 63  GLU C C   1 
ATOM   7691  O O   . GLU C 1 55  ? -77.789 48.001  39.687 1.00 55.67  ? 63  GLU C O   1 
ATOM   7692  C CB  . GLU C 1 55  ? -79.819 47.211  42.220 1.00 105.71 ? 63  GLU C CB  1 
ATOM   7693  C CG  . GLU C 1 55  ? -80.521 45.932  42.663 1.00 117.16 ? 63  GLU C CG  1 
ATOM   7694  C CD  . GLU C 1 55  ? -82.008 45.883  42.349 1.00 123.08 ? 63  GLU C CD  1 
ATOM   7695  O OE1 . GLU C 1 55  ? -82.826 46.841  42.515 1.00 92.82  ? 63  GLU C OE1 1 
ATOM   7696  O OE2 . GLU C 1 55  ? -82.316 44.782  41.866 1.00 145.38 ? 63  GLU C OE2 1 
ATOM   7697  N N   . ALA C 1 56  ? -77.455 49.265  41.514 1.00 68.38  ? 64  ALA C N   1 
ATOM   7698  C CA  . ALA C 1 56  ? -76.918 50.408  40.789 1.00 67.06  ? 64  ALA C CA  1 
ATOM   7699  C C   . ALA C 1 56  ? -75.641 50.042  40.002 1.00 75.66  ? 64  ALA C C   1 
ATOM   7700  O O   . ALA C 1 56  ? -75.474 50.472  38.862 1.00 76.53  ? 64  ALA C O   1 
ATOM   7701  C CB  . ALA C 1 56  ? -76.670 51.524  41.795 1.00 48.68  ? 64  ALA C CB  1 
ATOM   7702  N N   . LEU C 1 57  ? -74.716 49.312  40.680 1.00 74.56  ? 65  LEU C N   1 
ATOM   7703  C CA  . LEU C 1 57  ? -73.431 48.875  40.161 1.00 64.73  ? 65  LEU C CA  1 
ATOM   7704  C C   . LEU C 1 57  ? -73.604 48.010  38.915 1.00 70.12  ? 65  LEU C C   1 
ATOM   7705  O O   . LEU C 1 57  ? -72.708 47.990  38.097 1.00 67.67  ? 65  LEU C O   1 
ATOM   7706  C CB  . LEU C 1 57  ? -72.787 48.018  41.249 1.00 69.12  ? 65  LEU C CB  1 
ATOM   7707  C CG  . LEU C 1 57  ? -71.514 48.513  41.915 1.00 75.36  ? 65  LEU C CG  1 
ATOM   7708  C CD1 . LEU C 1 57  ? -70.706 47.274  42.289 1.00 77.62  ? 65  LEU C CD1 1 
ATOM   7709  C CD2 . LEU C 1 57  ? -70.767 49.331  40.877 1.00 70.23  ? 65  LEU C CD2 1 
ATOM   7710  N N   . GLY C 1 58  ? -74.672 47.184  38.891 1.00 69.37  ? 66  GLY C N   1 
ATOM   7711  C CA  . GLY C 1 58  ? -74.923 46.185  37.867 1.00 66.28  ? 66  GLY C CA  1 
ATOM   7712  C C   . GLY C 1 58  ? -75.387 46.807  36.557 1.00 73.86  ? 66  GLY C C   1 
ATOM   7713  O O   . GLY C 1 58  ? -75.286 46.150  35.526 1.00 98.65  ? 66  GLY C O   1 
ATOM   7714  N N   . SER C 1 59  ? -75.753 48.100  36.572 1.00 79.03  ? 67  SER C N   1 
ATOM   7715  C CA  . SER C 1 59  ? -76.529 48.753  35.517 1.00 110.45 ? 67  SER C CA  1 
ATOM   7716  C C   . SER C 1 59  ? -75.778 48.952  34.196 1.00 103.46 ? 67  SER C C   1 
ATOM   7717  O O   . SER C 1 59  ? -74.540 48.812  34.122 1.00 86.46  ? 67  SER C O   1 
ATOM   7718  C CB  . SER C 1 59  ? -77.075 50.061  36.006 1.00 129.27 ? 67  SER C CB  1 
ATOM   7719  O OG  . SER C 1 59  ? -75.999 50.947  36.274 1.00 112.61 ? 67  SER C OG  1 
ATOM   7720  N N   . CYS C 1 60  ? -76.586 49.307  33.171 1.00 94.78  ? 68  CYS C N   1 
ATOM   7721  C CA  . CYS C 1 60  ? -76.111 49.574  31.805 1.00 91.13  ? 68  CYS C CA  1 
ATOM   7722  C C   . CYS C 1 60  ? -75.260 50.843  31.743 1.00 81.13  ? 68  CYS C C   1 
ATOM   7723  O O   . CYS C 1 60  ? -74.740 51.180  30.688 1.00 88.42  ? 68  CYS C O   1 
ATOM   7724  C CB  . CYS C 1 60  ? -77.256 49.812  30.825 1.00 74.73  ? 68  CYS C CB  1 
ATOM   7725  S SG  . CYS C 1 60  ? -78.338 51.183  31.315 1.00 91.60  ? 68  CYS C SG  1 
ATOM   7726  N N   . LEU C 1 61  ? -75.164 51.565  32.882 1.00 75.79  ? 69  LEU C N   1 
ATOM   7727  C CA  . LEU C 1 61  ? -74.405 52.802  32.974 1.00 75.71  ? 69  LEU C CA  1 
ATOM   7728  C C   . LEU C 1 61  ? -72.950 52.496  32.631 1.00 80.76  ? 69  LEU C C   1 
ATOM   7729  O O   . LEU C 1 61  ? -72.168 53.399  32.331 1.00 84.87  ? 69  LEU C O   1 
ATOM   7730  C CB  . LEU C 1 61  ? -74.563 53.380  34.382 1.00 71.01  ? 69  LEU C CB  1 
ATOM   7731  C CG  . LEU C 1 61  ? -75.942 53.950  34.728 1.00 66.64  ? 69  LEU C CG  1 
ATOM   7732  C CD1 . LEU C 1 61  ? -76.106 54.399  36.153 1.00 52.55  ? 69  LEU C CD1 1 
ATOM   7733  C CD2 . LEU C 1 61  ? -76.051 55.145  33.832 1.00 83.42  ? 69  LEU C CD2 1 
ATOM   7734  N N   . ASN C 1 62  ? -72.599 51.200  32.698 1.00 75.50  ? 70  ASN C N   1 
ATOM   7735  C CA  . ASN C 1 62  ? -71.255 50.749  32.397 1.00 76.82  ? 70  ASN C CA  1 
ATOM   7736  C C   . ASN C 1 62  ? -70.845 51.228  31.002 1.00 86.28  ? 70  ASN C C   1 
ATOM   7737  O O   . ASN C 1 62  ? -69.665 51.493  30.754 1.00 105.29 ? 70  ASN C O   1 
ATOM   7738  C CB  . ASN C 1 62  ? -71.115 49.247  32.604 1.00 70.61  ? 70  ASN C CB  1 
ATOM   7739  C CG  . ASN C 1 62  ? -69.672 48.849  32.356 1.00 98.73  ? 70  ASN C CG  1 
ATOM   7740  O OD1 . ASN C 1 62  ? -69.371 48.067  31.436 1.00 109.39 ? 70  ASN C OD1 1 
ATOM   7741  N ND2 . ASN C 1 62  ? -68.752 49.336  33.180 1.00 94.48  ? 70  ASN C ND2 1 
ATOM   7742  N N   . ASN C 1 63  ? -71.848 51.323  30.120 1.00 103.30 ? 71  ASN C N   1 
ATOM   7743  C CA  . ASN C 1 63  ? -71.678 51.377  28.682 1.00 111.47 ? 71  ASN C CA  1 
ATOM   7744  C C   . ASN C 1 63  ? -71.281 52.758  28.172 1.00 109.21 ? 71  ASN C C   1 
ATOM   7745  O O   . ASN C 1 63  ? -70.578 52.835  27.153 1.00 149.00 ? 71  ASN C O   1 
ATOM   7746  C CB  . ASN C 1 63  ? -72.937 50.876  27.987 1.00 93.49  ? 71  ASN C CB  1 
ATOM   7747  C CG  . ASN C 1 63  ? -73.085 49.383  28.170 1.00 95.17  ? 71  ASN C CG  1 
ATOM   7748  O OD1 . ASN C 1 63  ? -72.099 48.650  28.355 1.00 109.29 ? 71  ASN C OD1 1 
ATOM   7749  N ND2 . ASN C 1 63  ? -74.323 48.938  28.154 1.00 96.30  ? 71  ASN C ND2 1 
ATOM   7750  N N   . LYS C 1 64  ? -71.722 53.817  28.863 1.00 79.33  ? 72  LYS C N   1 
ATOM   7751  C CA  . LYS C 1 64  ? -71.426 55.164  28.366 1.00 96.80  ? 72  LYS C CA  1 
ATOM   7752  C C   . LYS C 1 64  ? -70.055 55.715  28.791 1.00 91.78  ? 72  LYS C C   1 
ATOM   7753  O O   . LYS C 1 64  ? -69.648 55.709  29.963 1.00 92.15  ? 72  LYS C O   1 
ATOM   7754  C CB  . LYS C 1 64  ? -72.553 56.198  28.473 1.00 101.45 ? 72  LYS C CB  1 
ATOM   7755  C CG  . LYS C 1 64  ? -72.370 57.400  27.544 1.00 74.34  ? 72  LYS C CG  1 
ATOM   7756  C CD  . LYS C 1 64  ? -72.401 57.085  26.048 1.00 65.38  ? 72  LYS C CD  1 
ATOM   7757  C CE  . LYS C 1 64  ? -71.938 58.206  25.122 1.00 87.10  ? 72  LYS C CE  1 
ATOM   7758  N NZ  . LYS C 1 64  ? -70.531 58.562  24.792 1.00 49.23  ? 72  LYS C NZ  1 
ATOM   7759  N N   . TYR C 1 65  ? -69.347 56.252  27.782 1.00 66.04  ? 73  TYR C N   1 
ATOM   7760  C CA  . TYR C 1 65  ? -68.121 56.987  28.012 1.00 96.42  ? 73  TYR C CA  1 
ATOM   7761  C C   . TYR C 1 65  ? -68.543 58.420  28.281 1.00 92.33  ? 73  TYR C C   1 
ATOM   7762  O O   . TYR C 1 65  ? -69.298 58.978  27.468 1.00 92.66  ? 73  TYR C O   1 
ATOM   7763  C CB  . TYR C 1 65  ? -67.260 56.876  26.745 1.00 100.78 ? 73  TYR C CB  1 
ATOM   7764  C CG  . TYR C 1 65  ? -65.876 56.302  27.051 1.00 105.59 ? 73  TYR C CG  1 
ATOM   7765  C CD1 . TYR C 1 65  ? -65.620 54.932  27.102 1.00 80.28  ? 73  TYR C CD1 1 
ATOM   7766  C CD2 . TYR C 1 65  ? -64.814 57.156  27.324 1.00 118.71 ? 73  TYR C CD2 1 
ATOM   7767  C CE1 . TYR C 1 65  ? -64.357 54.441  27.404 1.00 76.20  ? 73  TYR C CE1 1 
ATOM   7768  C CE2 . TYR C 1 65  ? -63.540 56.674  27.615 1.00 128.54 ? 73  TYR C CE2 1 
ATOM   7769  C CZ  . TYR C 1 65  ? -63.306 55.307  27.663 1.00 103.04 ? 73  TYR C CZ  1 
ATOM   7770  O OH  . TYR C 1 65  ? -62.051 54.842  27.939 1.00 106.28 ? 73  TYR C OH  1 
ATOM   7771  N N   . SER C 1 66  ? -68.080 58.979  29.413 1.00 83.99  ? 74  SER C N   1 
ATOM   7772  C CA  . SER C 1 66  ? -68.459 60.358  29.685 1.00 104.47 ? 74  SER C CA  1 
ATOM   7773  C C   . SER C 1 66  ? -67.276 61.254  30.075 1.00 90.14  ? 74  SER C C   1 
ATOM   7774  O O   . SER C 1 66  ? -67.366 61.976  31.080 1.00 71.72  ? 74  SER C O   1 
ATOM   7775  C CB  . SER C 1 66  ? -69.587 60.418  30.712 1.00 124.44 ? 74  SER C CB  1 
ATOM   7776  O OG  . SER C 1 66  ? -69.247 59.769  31.923 1.00 129.01 ? 74  SER C OG  1 
ATOM   7777  N N   . GLU C 1 67  ? -66.198 61.220  29.271 1.00 67.04  ? 75  GLU C N   1 
ATOM   7778  C CA  . GLU C 1 67  ? -64.952 61.892  29.619 1.00 96.98  ? 75  GLU C CA  1 
ATOM   7779  C C   . GLU C 1 67  ? -65.184 63.371  29.948 1.00 109.22 ? 75  GLU C C   1 
ATOM   7780  O O   . GLU C 1 67  ? -65.864 64.091  29.202 1.00 91.08  ? 75  GLU C O   1 
ATOM   7781  C CB  . GLU C 1 67  ? -63.820 61.661  28.613 1.00 81.20  ? 75  GLU C CB  1 
ATOM   7782  C CG  . GLU C 1 67  ? -62.993 60.434  28.963 1.00 75.05  ? 75  GLU C CG  1 
ATOM   7783  C CD  . GLU C 1 67  ? -61.999 59.905  27.951 1.00 92.51  ? 75  GLU C CD  1 
ATOM   7784  O OE1 . GLU C 1 67  ? -62.218 60.383  26.816 1.00 96.39  ? 75  GLU C OE1 1 
ATOM   7785  O OE2 . GLU C 1 67  ? -61.116 59.018  28.193 1.00 77.27  ? 75  GLU C OE2 1 
ATOM   7786  N N   . GLY C 1 68  ? -64.597 63.811  31.071 1.00 93.33  ? 76  GLY C N   1 
ATOM   7787  C CA  . GLY C 1 68  ? -64.818 65.202  31.402 1.00 93.01  ? 76  GLY C CA  1 
ATOM   7788  C C   . GLY C 1 68  ? -65.830 65.302  32.530 1.00 91.99  ? 76  GLY C C   1 
ATOM   7789  O O   . GLY C 1 68  ? -65.880 64.402  33.347 1.00 125.10 ? 76  GLY C O   1 
ATOM   7790  N N   . TYR C 1 69  ? -66.628 66.370  32.538 1.00 87.15  ? 77  TYR C N   1 
ATOM   7791  C CA  . TYR C 1 69  ? -67.568 66.576  33.620 1.00 103.95 ? 77  TYR C CA  1 
ATOM   7792  C C   . TYR C 1 69  ? -68.915 67.060  33.087 1.00 126.17 ? 77  TYR C C   1 
ATOM   7793  O O   . TYR C 1 69  ? -69.031 67.479  31.930 1.00 148.27 ? 77  TYR C O   1 
ATOM   7794  C CB  . TYR C 1 69  ? -66.940 67.615  34.542 1.00 71.25  ? 77  TYR C CB  1 
ATOM   7795  C CG  . TYR C 1 69  ? -65.669 67.156  35.215 1.00 61.67  ? 77  TYR C CG  1 
ATOM   7796  C CD1 . TYR C 1 69  ? -65.702 66.387  36.375 1.00 72.65  ? 77  TYR C CD1 1 
ATOM   7797  C CD2 . TYR C 1 69  ? -64.439 67.569  34.742 1.00 79.90  ? 77  TYR C CD2 1 
ATOM   7798  C CE1 . TYR C 1 69  ? -64.538 66.044  37.053 1.00 68.75  ? 77  TYR C CE1 1 
ATOM   7799  C CE2 . TYR C 1 69  ? -63.265 67.265  35.415 1.00 81.09  ? 77  TYR C CE2 1 
ATOM   7800  C CZ  . TYR C 1 69  ? -63.313 66.480  36.557 1.00 88.03  ? 77  TYR C CZ  1 
ATOM   7801  O OH  . TYR C 1 69  ? -62.105 66.119  37.094 1.00 96.17  ? 77  TYR C OH  1 
ATOM   7802  N N   . PRO C 1 70  ? -69.993 67.026  33.912 1.00 102.41 ? 78  PRO C N   1 
ATOM   7803  C CA  . PRO C 1 70  ? -71.293 67.543  33.495 1.00 90.31  ? 78  PRO C CA  1 
ATOM   7804  C C   . PRO C 1 70  ? -71.105 68.982  33.013 1.00 102.52 ? 78  PRO C C   1 
ATOM   7805  O O   . PRO C 1 70  ? -70.511 69.791  33.737 1.00 86.82  ? 78  PRO C O   1 
ATOM   7806  C CB  . PRO C 1 70  ? -71.996 67.527  34.856 1.00 80.63  ? 78  PRO C CB  1 
ATOM   7807  C CG  . PRO C 1 70  ? -71.487 66.291  35.486 1.00 103.56 ? 78  PRO C CG  1 
ATOM   7808  C CD  . PRO C 1 70  ? -70.003 66.439  35.256 1.00 104.91 ? 78  PRO C CD  1 
ATOM   7809  N N   . GLY C 1 71  ? -71.590 69.275  31.791 1.00 104.66 ? 79  GLY C N   1 
ATOM   7810  C CA  . GLY C 1 71  ? -71.516 70.619  31.237 1.00 70.95  ? 79  GLY C CA  1 
ATOM   7811  C C   . GLY C 1 71  ? -70.127 70.947  30.699 1.00 90.97  ? 79  GLY C C   1 
ATOM   7812  O O   . GLY C 1 71  ? -69.881 72.092  30.340 1.00 117.59 ? 79  GLY C O   1 
ATOM   7813  N N   . GLN C 1 72  ? -69.216 69.971  30.720 1.00 106.04 ? 80  GLN C N   1 
ATOM   7814  C CA  . GLN C 1 72  ? -68.038 69.976  29.862 1.00 107.49 ? 80  GLN C CA  1 
ATOM   7815  C C   . GLN C 1 72  ? -67.691 68.548  29.467 1.00 114.05 ? 80  GLN C C   1 
ATOM   7816  O O   . GLN C 1 72  ? -66.629 68.056  29.869 1.00 147.51 ? 80  GLN C O   1 
ATOM   7817  C CB  . GLN C 1 72  ? -66.778 70.507  30.526 1.00 91.92  ? 80  GLN C CB  1 
ATOM   7818  C CG  . GLN C 1 72  ? -66.899 71.947  30.967 1.00 99.61  ? 80  GLN C CG  1 
ATOM   7819  C CD  . GLN C 1 72  ? -65.632 72.292  31.691 1.00 102.03 ? 80  GLN C CD  1 
ATOM   7820  O OE1 . GLN C 1 72  ? -64.809 73.057  31.163 1.00 116.79 ? 80  GLN C OE1 1 
ATOM   7821  N NE2 . GLN C 1 72  ? -65.455 71.667  32.860 1.00 80.62  ? 80  GLN C NE2 1 
ATOM   7822  N N   . ARG C 1 73  ? -68.561 67.913  28.659 1.00 84.27  ? 81  ARG C N   1 
ATOM   7823  C CA  . ARG C 1 73  ? -68.293 66.541  28.237 1.00 78.43  ? 81  ARG C CA  1 
ATOM   7824  C C   . ARG C 1 73  ? -67.477 66.551  26.959 1.00 88.52  ? 81  ARG C C   1 
ATOM   7825  O O   . ARG C 1 73  ? -67.454 67.550  26.249 1.00 115.15 ? 81  ARG C O   1 
ATOM   7826  C CB  . ARG C 1 73  ? -69.531 65.653  28.102 1.00 79.42  ? 81  ARG C CB  1 
ATOM   7827  C CG  . ARG C 1 73  ? -70.312 65.468  29.405 1.00 114.91 ? 81  ARG C CG  1 
ATOM   7828  C CD  . ARG C 1 73  ? -69.544 64.680  30.468 1.00 113.92 ? 81  ARG C CD  1 
ATOM   7829  N NE  . ARG C 1 73  ? -70.412 64.293  31.582 1.00 96.86  ? 81  ARG C NE  1 
ATOM   7830  C CZ  . ARG C 1 73  ? -70.106 63.614  32.692 1.00 130.18 ? 81  ARG C CZ  1 
ATOM   7831  N NH1 . ARG C 1 73  ? -68.857 63.245  32.993 1.00 136.83 ? 81  ARG C NH1 1 
ATOM   7832  N NH2 . ARG C 1 73  ? -71.121 63.299  33.491 1.00 125.35 ? 81  ARG C NH2 1 
ATOM   7833  N N   . TYR C 1 74  ? -66.779 65.442  26.699 1.00 100.23 ? 82  TYR C N   1 
ATOM   7834  C CA  . TYR C 1 74  ? -66.011 65.317  25.465 1.00 76.27  ? 82  TYR C CA  1 
ATOM   7835  C C   . TYR C 1 74  ? -66.708 64.289  24.587 1.00 91.27  ? 82  TYR C C   1 
ATOM   7836  O O   . TYR C 1 74  ? -66.328 64.110  23.445 1.00 134.76 ? 82  TYR C O   1 
ATOM   7837  C CB  . TYR C 1 74  ? -64.531 64.946  25.639 1.00 70.76  ? 82  TYR C CB  1 
ATOM   7838  C CG  . TYR C 1 74  ? -63.658 65.988  26.331 1.00 83.86  ? 82  TYR C CG  1 
ATOM   7839  C CD1 . TYR C 1 74  ? -63.800 66.251  27.701 1.00 109.49 ? 82  TYR C CD1 1 
ATOM   7840  C CD2 . TYR C 1 74  ? -62.746 66.754  25.613 1.00 87.09  ? 82  TYR C CD2 1 
ATOM   7841  C CE1 . TYR C 1 74  ? -63.075 67.261  28.321 1.00 111.86 ? 82  TYR C CE1 1 
ATOM   7842  C CE2 . TYR C 1 74  ? -62.014 67.762  26.227 1.00 93.50  ? 82  TYR C CE2 1 
ATOM   7843  C CZ  . TYR C 1 74  ? -62.193 68.029  27.573 1.00 101.01 ? 82  TYR C CZ  1 
ATOM   7844  O OH  . TYR C 1 74  ? -61.458 69.023  28.141 1.00 103.87 ? 82  TYR C OH  1 
ATOM   7845  N N   . TYR C 1 75  ? -67.745 63.658  25.130 1.00 99.11  ? 83  TYR C N   1 
ATOM   7846  C CA  . TYR C 1 75  ? -68.619 62.831  24.318 1.00 88.25  ? 83  TYR C CA  1 
ATOM   7847  C C   . TYR C 1 75  ? -70.046 63.373  24.448 1.00 85.61  ? 83  TYR C C   1 
ATOM   7848  O O   . TYR C 1 75  ? -70.428 63.882  25.502 1.00 88.37  ? 83  TYR C O   1 
ATOM   7849  C CB  . TYR C 1 75  ? -68.499 61.413  24.869 1.00 82.82  ? 83  TYR C CB  1 
ATOM   7850  C CG  . TYR C 1 75  ? -67.161 60.694  24.737 1.00 109.22 ? 83  TYR C CG  1 
ATOM   7851  C CD1 . TYR C 1 75  ? -66.651 60.305  23.497 1.00 119.50 ? 83  TYR C CD1 1 
ATOM   7852  C CD2 . TYR C 1 75  ? -66.447 60.331  25.870 1.00 100.54 ? 83  TYR C CD2 1 
ATOM   7853  C CE1 . TYR C 1 75  ? -65.466 59.579  23.408 1.00 137.07 ? 83  TYR C CE1 1 
ATOM   7854  C CE2 . TYR C 1 75  ? -65.269 59.600  25.797 1.00 93.43  ? 83  TYR C CE2 1 
ATOM   7855  C CZ  . TYR C 1 75  ? -64.765 59.223  24.561 1.00 118.13 ? 83  TYR C CZ  1 
ATOM   7856  O OH  . TYR C 1 75  ? -63.616 58.458  24.481 1.00 85.22  ? 83  TYR C OH  1 
ATOM   7857  N N   . GLY C 1 76  ? -70.840 63.291  23.366 1.00 73.94  ? 84  GLY C N   1 
ATOM   7858  C CA  . GLY C 1 76  ? -72.274 63.571  23.423 1.00 72.90  ? 84  GLY C CA  1 
ATOM   7859  C C   . GLY C 1 76  ? -73.078 62.437  24.072 1.00 92.72  ? 84  GLY C C   1 
ATOM   7860  O O   . GLY C 1 76  ? -72.576 61.336  24.317 1.00 117.62 ? 84  GLY C O   1 
ATOM   7861  N N   . GLY C 1 77  ? -74.355 62.723  24.351 1.00 101.63 ? 85  GLY C N   1 
ATOM   7862  C CA  . GLY C 1 77  ? -75.324 61.717  24.771 1.00 115.09 ? 85  GLY C CA  1 
ATOM   7863  C C   . GLY C 1 77  ? -75.185 61.367  26.247 1.00 96.09  ? 85  GLY C C   1 
ATOM   7864  O O   . GLY C 1 77  ? -75.537 60.281  26.719 1.00 110.43 ? 85  GLY C O   1 
ATOM   7865  N N   . THR C 1 78  ? -74.653 62.339  26.973 1.00 81.52  ? 86  THR C N   1 
ATOM   7866  C CA  . THR C 1 78  ? -74.465 62.190  28.399 1.00 98.54  ? 86  THR C CA  1 
ATOM   7867  C C   . THR C 1 78  ? -75.626 62.775  29.201 1.00 82.36  ? 86  THR C C   1 
ATOM   7868  O O   . THR C 1 78  ? -75.470 63.026  30.399 1.00 80.35  ? 86  THR C O   1 
ATOM   7869  C CB  . THR C 1 78  ? -73.122 62.816  28.783 1.00 105.41 ? 86  THR C CB  1 
ATOM   7870  O OG1 . THR C 1 78  ? -73.174 64.191  28.426 1.00 68.73  ? 86  THR C OG1 1 
ATOM   7871  C CG2 . THR C 1 78  ? -71.963 62.156  28.061 1.00 109.98 ? 86  THR C CG2 1 
ATOM   7872  N N   . GLU C 1 79  ? -76.784 62.963  28.569 1.00 86.93  ? 87  GLU C N   1 
ATOM   7873  C CA  . GLU C 1 79  ? -77.880 63.646  29.247 1.00 112.16 ? 87  GLU C CA  1 
ATOM   7874  C C   . GLU C 1 79  ? -78.236 62.947  30.572 1.00 107.13 ? 87  GLU C C   1 
ATOM   7875  O O   . GLU C 1 79  ? -78.430 63.611  31.601 1.00 102.97 ? 87  GLU C O   1 
ATOM   7876  C CB  . GLU C 1 79  ? -79.076 63.844  28.312 1.00 124.82 ? 87  GLU C CB  1 
ATOM   7877  C CG  . GLU C 1 79  ? -80.296 64.339  29.085 1.00 137.08 ? 87  GLU C CG  1 
ATOM   7878  C CD  . GLU C 1 79  ? -81.643 64.014  28.475 1.00 133.26 ? 87  GLU C CD  1 
ATOM   7879  O OE1 . GLU C 1 79  ? -81.704 62.983  27.798 1.00 95.05  ? 87  GLU C OE1 1 
ATOM   7880  O OE2 . GLU C 1 79  ? -82.605 64.803  28.619 1.00 158.61 ? 87  GLU C OE2 1 
ATOM   7881  N N   . PHE C 1 80  ? -78.329 61.604  30.547 1.00 84.00  ? 88  PHE C N   1 
ATOM   7882  C CA  . PHE C 1 80  ? -78.715 60.877  31.747 1.00 92.74  ? 88  PHE C CA  1 
ATOM   7883  C C   . PHE C 1 80  ? -77.523 60.709  32.683 1.00 108.72 ? 88  PHE C C   1 
ATOM   7884  O O   . PHE C 1 80  ? -77.699 60.719  33.902 1.00 115.88 ? 88  PHE C O   1 
ATOM   7885  C CB  . PHE C 1 80  ? -79.454 59.557  31.514 1.00 104.86 ? 88  PHE C CB  1 
ATOM   7886  C CG  . PHE C 1 80  ? -80.707 59.821  30.706 1.00 106.87 ? 88  PHE C CG  1 
ATOM   7887  C CD1 . PHE C 1 80  ? -81.708 60.647  31.218 1.00 102.08 ? 88  PHE C CD1 1 
ATOM   7888  C CD2 . PHE C 1 80  ? -80.834 59.304  29.417 1.00 101.88 ? 88  PHE C CD2 1 
ATOM   7889  C CE1 . PHE C 1 80  ? -82.833 60.915  30.459 1.00 99.22  ? 88  PHE C CE1 1 
ATOM   7890  C CE2 . PHE C 1 80  ? -81.955 59.589  28.647 1.00 109.81 ? 88  PHE C CE2 1 
ATOM   7891  C CZ  . PHE C 1 80  ? -82.954 60.385  29.181 1.00 119.16 ? 88  PHE C CZ  1 
ATOM   7892  N N   . ILE C 1 81  ? -76.327 60.527  32.106 1.00 110.94 ? 89  ILE C N   1 
ATOM   7893  C CA  . ILE C 1 81  ? -75.114 60.433  32.906 1.00 105.53 ? 89  ILE C CA  1 
ATOM   7894  C C   . ILE C 1 81  ? -74.975 61.727  33.719 1.00 103.51 ? 89  ILE C C   1 
ATOM   7895  O O   . ILE C 1 81  ? -74.539 61.742  34.879 1.00 102.91 ? 89  ILE C O   1 
ATOM   7896  C CB  . ILE C 1 81  ? -73.890 60.229  31.993 1.00 117.43 ? 89  ILE C CB  1 
ATOM   7897  C CG1 . ILE C 1 81  ? -73.994 58.985  31.067 1.00 128.02 ? 89  ILE C CG1 1 
ATOM   7898  C CG2 . ILE C 1 81  ? -72.551 60.365  32.724 1.00 127.95 ? 89  ILE C CG2 1 
ATOM   7899  C CD1 . ILE C 1 81  ? -74.382 57.682  31.739 1.00 114.37 ? 89  ILE C CD1 1 
ATOM   7900  N N   . ASP C 1 82  ? -75.344 62.835  33.076 1.00 78.47  ? 90  ASP C N   1 
ATOM   7901  C CA  . ASP C 1 82  ? -75.181 64.126  33.693 1.00 79.53  ? 90  ASP C CA  1 
ATOM   7902  C C   . ASP C 1 82  ? -76.145 64.254  34.858 1.00 94.71  ? 90  ASP C C   1 
ATOM   7903  O O   . ASP C 1 82  ? -75.747 64.780  35.901 1.00 80.94  ? 90  ASP C O   1 
ATOM   7904  C CB  . ASP C 1 82  ? -75.321 65.204  32.651 1.00 78.75  ? 90  ASP C CB  1 
ATOM   7905  C CG  . ASP C 1 82  ? -74.149 65.241  31.695 1.00 81.14  ? 90  ASP C CG  1 
ATOM   7906  O OD1 . ASP C 1 82  ? -73.057 64.756  32.073 1.00 86.16  ? 90  ASP C OD1 1 
ATOM   7907  O OD2 . ASP C 1 82  ? -74.394 65.642  30.553 1.00 91.77  ? 90  ASP C OD2 1 
ATOM   7908  N N   . GLU C 1 83  ? -77.381 63.746  34.678 1.00 98.83  ? 91  GLU C N   1 
ATOM   7909  C CA  . GLU C 1 83  ? -78.342 63.744  35.772 1.00 120.19 ? 91  GLU C CA  1 
ATOM   7910  C C   . GLU C 1 83  ? -77.686 63.053  36.965 1.00 118.15 ? 91  GLU C C   1 
ATOM   7911  O O   . GLU C 1 83  ? -77.648 63.588  38.091 1.00 113.27 ? 91  GLU C O   1 
ATOM   7912  C CB  . GLU C 1 83  ? -79.623 62.938  35.546 1.00 106.64 ? 91  GLU C CB  1 
ATOM   7913  C CG  . GLU C 1 83  ? -80.592 63.443  34.480 1.00 150.36 ? 91  GLU C CG  1 
ATOM   7914  C CD  . GLU C 1 83  ? -82.007 62.923  34.788 1.00 153.66 ? 91  GLU C CD  1 
ATOM   7915  O OE1 . GLU C 1 83  ? -82.233 62.503  35.976 1.00 93.90  ? 91  GLU C OE1 1 
ATOM   7916  O OE2 . GLU C 1 83  ? -82.872 62.906  33.850 1.00 139.32 ? 91  GLU C OE2 1 
ATOM   7917  N N   . LEU C 1 84  ? -77.139 61.868  36.646 1.00 100.32 ? 92  LEU C N   1 
ATOM   7918  C CA  . LEU C 1 84  ? -76.617 60.961  37.641 1.00 78.30  ? 92  LEU C CA  1 
ATOM   7919  C C   . LEU C 1 84  ? -75.462 61.620  38.381 1.00 88.76  ? 92  LEU C C   1 
ATOM   7920  O O   . LEU C 1 84  ? -75.531 61.713  39.613 1.00 89.38  ? 92  LEU C O   1 
ATOM   7921  C CB  . LEU C 1 84  ? -76.179 59.666  36.983 1.00 54.93  ? 92  LEU C CB  1 
ATOM   7922  C CG  . LEU C 1 84  ? -75.391 58.737  37.900 1.00 53.83  ? 92  LEU C CG  1 
ATOM   7923  C CD1 . LEU C 1 84  ? -76.372 58.234  38.930 1.00 49.13  ? 92  LEU C CD1 1 
ATOM   7924  C CD2 . LEU C 1 84  ? -74.767 57.635  37.089 1.00 72.11  ? 92  LEU C CD2 1 
ATOM   7925  N N   . GLU C 1 85  ? -74.415 62.031  37.638 1.00 67.53  ? 93  GLU C N   1 
ATOM   7926  C CA  . GLU C 1 85  ? -73.235 62.609  38.281 1.00 73.52  ? 93  GLU C CA  1 
ATOM   7927  C C   . GLU C 1 85  ? -73.626 63.814  39.147 1.00 81.69  ? 93  GLU C C   1 
ATOM   7928  O O   . GLU C 1 85  ? -73.223 63.929  40.304 1.00 65.11  ? 93  GLU C O   1 
ATOM   7929  C CB  . GLU C 1 85  ? -72.190 63.052  37.260 1.00 63.18  ? 93  GLU C CB  1 
ATOM   7930  C CG  . GLU C 1 85  ? -70.864 63.501  37.865 1.00 51.33  ? 93  GLU C CG  1 
ATOM   7931  C CD  . GLU C 1 85  ? -69.677 63.207  36.883 1.00 94.53  ? 93  GLU C CD  1 
ATOM   7932  O OE1 . GLU C 1 85  ? -69.781 62.618  35.736 1.00 91.97  ? 93  GLU C OE1 1 
ATOM   7933  O OE2 . GLU C 1 85  ? -68.560 63.677  37.213 1.00 89.15  ? 93  GLU C OE2 1 
ATOM   7934  N N   . THR C 1 86  ? -74.493 64.673  38.600 1.00 87.02  ? 94  THR C N   1 
ATOM   7935  C CA  . THR C 1 86  ? -74.843 65.868  39.347 1.00 76.59  ? 94  THR C CA  1 
ATOM   7936  C C   . THR C 1 86  ? -75.642 65.444  40.577 1.00 80.19  ? 94  THR C C   1 
ATOM   7937  O O   . THR C 1 86  ? -75.343 65.917  41.682 1.00 68.13  ? 94  THR C O   1 
ATOM   7938  C CB  . THR C 1 86  ? -75.458 66.979  38.486 1.00 73.34  ? 94  THR C CB  1 
ATOM   7939  O OG1 . THR C 1 86  ? -74.801 66.981  37.226 1.00 87.87  ? 94  THR C OG1 1 
ATOM   7940  C CG2 . THR C 1 86  ? -74.901 68.373  38.757 1.00 47.04  ? 94  THR C CG2 1 
ATOM   7941  N N   . LEU C 1 87  ? -76.602 64.516  40.392 1.00 82.46  ? 95  LEU C N   1 
ATOM   7942  C CA  . LEU C 1 87  ? -77.382 64.000  41.518 1.00 87.91  ? 95  LEU C CA  1 
ATOM   7943  C C   . LEU C 1 87  ? -76.420 63.523  42.613 1.00 89.70  ? 95  LEU C C   1 
ATOM   7944  O O   . LEU C 1 87  ? -76.533 63.882  43.799 1.00 59.99  ? 95  LEU C O   1 
ATOM   7945  C CB  . LEU C 1 87  ? -78.347 62.889  41.091 1.00 71.71  ? 95  LEU C CB  1 
ATOM   7946  C CG  . LEU C 1 87  ? -79.093 62.154  42.222 1.00 84.23  ? 95  LEU C CG  1 
ATOM   7947  C CD1 . LEU C 1 87  ? -79.980 62.977  43.158 1.00 88.64  ? 95  LEU C CD1 1 
ATOM   7948  C CD2 . LEU C 1 87  ? -79.913 61.036  41.637 1.00 90.83  ? 95  LEU C CD2 1 
ATOM   7949  N N   . CYS C 1 88  ? -75.452 62.703  42.187 1.00 91.35  ? 96  CYS C N   1 
ATOM   7950  C CA  . CYS C 1 88  ? -74.520 62.109  43.129 1.00 96.46  ? 96  CYS C CA  1 
ATOM   7951  C C   . CYS C 1 88  ? -73.790 63.190  43.929 1.00 100.04 ? 96  CYS C C   1 
ATOM   7952  O O   . CYS C 1 88  ? -73.697 63.112  45.167 1.00 102.53 ? 96  CYS C O   1 
ATOM   7953  C CB  . CYS C 1 88  ? -73.472 61.266  42.429 1.00 78.58  ? 96  CYS C CB  1 
ATOM   7954  S SG  . CYS C 1 88  ? -72.810 60.073  43.610 1.00 84.99  ? 96  CYS C SG  1 
ATOM   7955  N N   . GLN C 1 89  ? -73.266 64.194  43.206 1.00 69.94  ? 97  GLN C N   1 
ATOM   7956  C CA  . GLN C 1 89  ? -72.530 65.271  43.843 1.00 70.82  ? 97  GLN C CA  1 
ATOM   7957  C C   . GLN C 1 89  ? -73.418 66.004  44.849 1.00 93.33  ? 97  GLN C C   1 
ATOM   7958  O O   . GLN C 1 89  ? -72.949 66.357  45.946 1.00 81.73  ? 97  GLN C O   1 
ATOM   7959  C CB  . GLN C 1 89  ? -72.019 66.222  42.768 1.00 65.22  ? 97  GLN C CB  1 
ATOM   7960  C CG  . GLN C 1 89  ? -70.653 65.837  42.223 1.00 71.87  ? 97  GLN C CG  1 
ATOM   7961  C CD  . GLN C 1 89  ? -70.484 66.069  40.728 1.00 99.82  ? 97  GLN C CD  1 
ATOM   7962  O OE1 . GLN C 1 89  ? -71.352 66.683  40.074 1.00 75.45  ? 97  GLN C OE1 1 
ATOM   7963  N NE2 . GLN C 1 89  ? -69.387 65.507  40.203 1.00 74.59  ? 97  GLN C NE2 1 
ATOM   7964  N N   . LYS C 1 90  ? -74.676 66.247  44.438 1.00 86.04  ? 98  LYS C N   1 
ATOM   7965  C CA  . LYS C 1 90  ? -75.642 66.927  45.283 1.00 94.71  ? 98  LYS C CA  1 
ATOM   7966  C C   . LYS C 1 90  ? -75.778 66.153  46.601 1.00 102.26 ? 98  LYS C C   1 
ATOM   7967  O O   . LYS C 1 90  ? -75.663 66.744  47.680 1.00 112.21 ? 98  LYS C O   1 
ATOM   7968  C CB  . LYS C 1 90  ? -76.946 67.170  44.516 1.00 84.59  ? 98  LYS C CB  1 
ATOM   7969  C CG  . LYS C 1 90  ? -78.062 67.778  45.377 1.00 90.97  ? 98  LYS C CG  1 
ATOM   7970  C CD  . LYS C 1 90  ? -79.337 68.108  44.613 1.00 123.37 ? 98  LYS C CD  1 
ATOM   7971  C CE  . LYS C 1 90  ? -80.247 66.951  44.267 1.00 138.81 ? 98  LYS C CE  1 
ATOM   7972  N NZ  . LYS C 1 90  ? -80.777 66.279  45.463 1.00 92.39  ? 98  LYS C NZ  1 
ATOM   7973  N N   . ARG C 1 91  ? -75.971 64.828  46.489 1.00 80.10  ? 99  ARG C N   1 
ATOM   7974  C CA  . ARG C 1 91  ? -76.196 63.997  47.667 1.00 102.50 ? 99  ARG C CA  1 
ATOM   7975  C C   . ARG C 1 91  ? -74.950 63.924  48.548 1.00 104.88 ? 99  ARG C C   1 
ATOM   7976  O O   . ARG C 1 91  ? -75.028 63.878  49.787 1.00 102.67 ? 99  ARG C O   1 
ATOM   7977  C CB  . ARG C 1 91  ? -76.625 62.586  47.266 1.00 94.18  ? 99  ARG C CB  1 
ATOM   7978  C CG  . ARG C 1 91  ? -77.993 62.533  46.608 1.00 83.41  ? 99  ARG C CG  1 
ATOM   7979  C CD  . ARG C 1 91  ? -78.286 61.100  46.316 1.00 81.26  ? 99  ARG C CD  1 
ATOM   7980  N NE  . ARG C 1 91  ? -79.582 60.863  45.692 1.00 77.72  ? 99  ARG C NE  1 
ATOM   7981  C CZ  . ARG C 1 91  ? -80.003 59.656  45.372 1.00 100.09 ? 99  ARG C CZ  1 
ATOM   7982  N NH1 . ARG C 1 91  ? -79.233 58.606  45.623 1.00 99.30  ? 99  ARG C NH1 1 
ATOM   7983  N NH2 . ARG C 1 91  ? -81.241 59.481  44.928 1.00 113.95 ? 99  ARG C NH2 1 
ATOM   7984  N N   . ALA C 1 92  ? -73.788 63.926  47.895 1.00 95.68  ? 100 ALA C N   1 
ATOM   7985  C CA  . ALA C 1 92  ? -72.549 63.894  48.647 1.00 111.12 ? 100 ALA C CA  1 
ATOM   7986  C C   . ALA C 1 92  ? -72.467 65.113  49.572 1.00 122.03 ? 100 ALA C C   1 
ATOM   7987  O O   . ALA C 1 92  ? -72.156 64.980  50.766 1.00 134.40 ? 100 ALA C O   1 
ATOM   7988  C CB  . ALA C 1 92  ? -71.371 63.810  47.709 1.00 103.11 ? 100 ALA C CB  1 
ATOM   7989  N N   . LEU C 1 93  ? -72.706 66.305  49.000 1.00 89.73  ? 101 LEU C N   1 
ATOM   7990  C CA  . LEU C 1 93  ? -72.595 67.535  49.770 1.00 102.04 ? 101 LEU C CA  1 
ATOM   7991  C C   . LEU C 1 93  ? -73.651 67.536  50.879 1.00 92.64  ? 101 LEU C C   1 
ATOM   7992  O O   . LEU C 1 93  ? -73.390 68.038  51.976 1.00 66.82  ? 101 LEU C O   1 
ATOM   7993  C CB  . LEU C 1 93  ? -72.665 68.755  48.848 1.00 89.09  ? 101 LEU C CB  1 
ATOM   7994  C CG  . LEU C 1 93  ? -71.550 68.842  47.805 1.00 67.15  ? 101 LEU C CG  1 
ATOM   7995  C CD1 . LEU C 1 93  ? -71.792 69.904  46.825 1.00 63.18  ? 101 LEU C CD1 1 
ATOM   7996  C CD2 . LEU C 1 93  ? -70.256 69.190  48.487 1.00 71.98  ? 101 LEU C CD2 1 
ATOM   7997  N N   . GLN C 1 94  ? -74.838 66.985  50.567 1.00 80.38  ? 102 GLN C N   1 
ATOM   7998  C CA  . GLN C 1 94  ? -75.935 66.927  51.526 1.00 92.32  ? 102 GLN C CA  1 
ATOM   7999  C C   . GLN C 1 94  ? -75.516 66.091  52.731 1.00 98.16  ? 102 GLN C C   1 
ATOM   8000  O O   . GLN C 1 94  ? -75.511 66.578  53.869 1.00 86.25  ? 102 GLN C O   1 
ATOM   8001  C CB  . GLN C 1 94  ? -77.250 66.332  50.990 1.00 66.86  ? 102 GLN C CB  1 
ATOM   8002  C CG  . GLN C 1 94  ? -78.333 67.357  50.664 1.00 68.30  ? 102 GLN C CG  1 
ATOM   8003  C CD  . GLN C 1 94  ? -79.206 66.827  49.554 1.00 98.35  ? 102 GLN C CD  1 
ATOM   8004  O OE1 . GLN C 1 94  ? -79.240 67.312  48.396 1.00 92.29  ? 102 GLN C OE1 1 
ATOM   8005  N NE2 . GLN C 1 94  ? -79.782 65.692  49.923 1.00 91.81  ? 102 GLN C NE2 1 
ATOM   8006  N N   . ALA C 1 95  ? -75.156 64.829  52.454 1.00 97.78  ? 103 ALA C N   1 
ATOM   8007  C CA  . ALA C 1 95  ? -74.868 63.865  53.506 1.00 80.09  ? 103 ALA C CA  1 
ATOM   8008  C C   . ALA C 1 95  ? -73.904 64.463  54.540 1.00 100.44 ? 103 ALA C C   1 
ATOM   8009  O O   . ALA C 1 95  ? -73.969 64.153  55.741 1.00 76.30  ? 103 ALA C O   1 
ATOM   8010  C CB  . ALA C 1 95  ? -74.291 62.634  52.866 1.00 64.41  ? 103 ALA C CB  1 
ATOM   8011  N N   . TYR C 1 96  ? -73.012 65.352  54.064 1.00 101.21 ? 104 TYR C N   1 
ATOM   8012  C CA  . TYR C 1 96  ? -71.996 65.929  54.933 1.00 73.61  ? 104 TYR C CA  1 
ATOM   8013  C C   . TYR C 1 96  ? -72.352 67.348  55.340 1.00 82.68  ? 104 TYR C C   1 
ATOM   8014  O O   . TYR C 1 96  ? -71.493 67.988  55.925 1.00 100.29 ? 104 TYR C O   1 
ATOM   8015  C CB  . TYR C 1 96  ? -70.570 65.820  54.399 1.00 68.16  ? 104 TYR C CB  1 
ATOM   8016  C CG  . TYR C 1 96  ? -70.130 64.359  54.359 1.00 98.71  ? 104 TYR C CG  1 
ATOM   8017  C CD1 . TYR C 1 96  ? -69.578 63.711  55.472 1.00 100.35 ? 104 TYR C CD1 1 
ATOM   8018  C CD2 . TYR C 1 96  ? -70.291 63.615  53.201 1.00 99.63  ? 104 TYR C CD2 1 
ATOM   8019  C CE1 . TYR C 1 96  ? -69.238 62.371  55.440 1.00 102.74 ? 104 TYR C CE1 1 
ATOM   8020  C CE2 . TYR C 1 96  ? -69.945 62.273  53.165 1.00 126.82 ? 104 TYR C CE2 1 
ATOM   8021  C CZ  . TYR C 1 96  ? -69.389 61.649  54.269 1.00 113.02 ? 104 TYR C CZ  1 
ATOM   8022  O OH  . TYR C 1 96  ? -69.052 60.321  54.133 1.00 89.03  ? 104 TYR C OH  1 
ATOM   8023  N N   . LYS C 1 97  ? -73.601 67.788  55.052 1.00 93.06  ? 105 LYS C N   1 
ATOM   8024  C CA  . LYS C 1 97  ? -74.171 69.059  55.498 1.00 81.66  ? 105 LYS C CA  1 
ATOM   8025  C C   . LYS C 1 97  ? -73.194 70.163  55.094 1.00 74.76  ? 105 LYS C C   1 
ATOM   8026  O O   . LYS C 1 97  ? -72.798 71.005  55.891 1.00 99.37  ? 105 LYS C O   1 
ATOM   8027  C CB  . LYS C 1 97  ? -74.624 69.061  56.979 1.00 69.31  ? 105 LYS C CB  1 
ATOM   8028  C CG  . LYS C 1 97  ? -75.816 68.114  57.368 1.00 61.19  ? 105 LYS C CG  1 
ATOM   8029  C CD  . LYS C 1 97  ? -76.543 68.240  58.719 1.00 63.23  ? 105 LYS C CD  1 
ATOM   8030  C CE  . LYS C 1 97  ? -77.865 68.999  59.064 1.00 94.53  ? 105 LYS C CE  1 
ATOM   8031  N NZ  . LYS C 1 97  ? -79.107 68.373  59.603 1.00 73.47  ? 105 LYS C NZ  1 
ATOM   8032  N N   . LEU C 1 98  ? -72.791 70.152  53.832 1.00 69.34  ? 106 LEU C N   1 
ATOM   8033  C CA  . LEU C 1 98  ? -71.903 71.191  53.338 1.00 81.49  ? 106 LEU C CA  1 
ATOM   8034  C C   . LEU C 1 98  ? -72.712 72.148  52.462 1.00 84.73  ? 106 LEU C C   1 
ATOM   8035  O O   . LEU C 1 98  ? -73.470 71.707  51.573 1.00 71.14  ? 106 LEU C O   1 
ATOM   8036  C CB  . LEU C 1 98  ? -70.812 70.535  52.492 1.00 92.99  ? 106 LEU C CB  1 
ATOM   8037  C CG  . LEU C 1 98  ? -70.037 69.387  53.126 1.00 73.85  ? 106 LEU C CG  1 
ATOM   8038  C CD1 . LEU C 1 98  ? -69.015 68.777  52.181 1.00 65.10  ? 106 LEU C CD1 1 
ATOM   8039  C CD2 . LEU C 1 98  ? -69.368 69.963  54.318 1.00 52.42  ? 106 LEU C CD2 1 
ATOM   8040  N N   . ASP C 1 99  ? -72.458 73.456  52.642 1.00 65.43  ? 107 ASP C N   1 
ATOM   8041  C CA  . ASP C 1 99  ? -72.982 74.471  51.729 1.00 62.71  ? 107 ASP C CA  1 
ATOM   8042  C C   . ASP C 1 99  ? -72.350 74.358  50.327 1.00 51.75  ? 107 ASP C C   1 
ATOM   8043  O O   . ASP C 1 99  ? -71.121 74.490  50.175 1.00 64.75  ? 107 ASP C O   1 
ATOM   8044  C CB  . ASP C 1 99  ? -72.832 75.875  52.321 1.00 73.81  ? 107 ASP C CB  1 
ATOM   8045  C CG  . ASP C 1 99  ? -73.241 76.946  51.329 1.00 75.86  ? 107 ASP C CG  1 
ATOM   8046  O OD1 . ASP C 1 99  ? -74.389 76.887  50.857 1.00 115.03 ? 107 ASP C OD1 1 
ATOM   8047  O OD2 . ASP C 1 99  ? -72.376 77.715  50.890 1.00 62.93  ? 107 ASP C OD2 1 
ATOM   8048  N N   . PRO C 1 100 ? -73.126 74.093  49.257 1.00 50.13  ? 108 PRO C N   1 
ATOM   8049  C CA  . PRO C 1 100 ? -72.551 73.956  47.912 1.00 67.23  ? 108 PRO C CA  1 
ATOM   8050  C C   . PRO C 1 100 ? -71.821 75.196  47.404 1.00 77.96  ? 108 PRO C C   1 
ATOM   8051  O O   . PRO C 1 100 ? -71.089 75.128  46.419 1.00 81.56  ? 108 PRO C O   1 
ATOM   8052  C CB  . PRO C 1 100 ? -73.686 73.526  46.973 1.00 49.50  ? 108 PRO C CB  1 
ATOM   8053  C CG  . PRO C 1 100 ? -74.724 73.010  47.960 1.00 55.08  ? 108 PRO C CG  1 
ATOM   8054  C CD  . PRO C 1 100 ? -74.561 73.810  49.270 1.00 55.51  ? 108 PRO C CD  1 
ATOM   8055  N N   . GLN C 1 101 ? -71.995 76.324  48.099 1.00 65.31  ? 109 GLN C N   1 
ATOM   8056  C CA  . GLN C 1 101 ? -71.269 77.514  47.714 1.00 90.92  ? 109 GLN C CA  1 
ATOM   8057  C C   . GLN C 1 101 ? -69.906 77.540  48.386 1.00 91.86  ? 109 GLN C C   1 
ATOM   8058  O O   . GLN C 1 101 ? -69.035 78.317  48.034 1.00 104.53 ? 109 GLN C O   1 
ATOM   8059  C CB  . GLN C 1 101 ? -72.130 78.665  48.177 1.00 106.39 ? 109 GLN C CB  1 
ATOM   8060  C CG  . GLN C 1 101 ? -72.772 79.379  47.001 1.00 121.14 ? 109 GLN C CG  1 
ATOM   8061  C CD  . GLN C 1 101 ? -72.506 80.840  47.204 1.00 110.73 ? 109 GLN C CD  1 
ATOM   8062  O OE1 . GLN C 1 101 ? -72.537 81.271  48.363 1.00 65.24  ? 109 GLN C OE1 1 
ATOM   8063  N NE2 . GLN C 1 101 ? -72.100 81.527  46.139 1.00 126.50 ? 109 GLN C NE2 1 
ATOM   8064  N N   . CYS C 1 102 ? -69.711 76.658  49.353 1.00 91.26  ? 110 CYS C N   1 
ATOM   8065  C CA  . CYS C 1 102 ? -68.433 76.667  50.040 1.00 99.94  ? 110 CYS C CA  1 
ATOM   8066  C C   . CYS C 1 102 ? -67.645 75.387  49.812 1.00 100.19 ? 110 CYS C C   1 
ATOM   8067  O O   . CYS C 1 102 ? -66.465 75.333  50.197 1.00 94.07  ? 110 CYS C O   1 
ATOM   8068  C CB  . CYS C 1 102 ? -68.600 76.660  51.544 1.00 96.62  ? 110 CYS C CB  1 
ATOM   8069  S SG  . CYS C 1 102 ? -69.240 78.233  52.105 1.00 109.82 ? 110 CYS C SG  1 
ATOM   8070  N N   . TRP C 1 103 ? -68.366 74.379  49.295 1.00 67.43  ? 111 TRP C N   1 
ATOM   8071  C CA  . TRP C 1 103 ? -67.771 73.091  49.051 1.00 80.79  ? 111 TRP C CA  1 
ATOM   8072  C C   . TRP C 1 103 ? -68.225 72.557  47.711 1.00 95.67  ? 111 TRP C C   1 
ATOM   8073  O O   . TRP C 1 103 ? -69.375 72.698  47.306 1.00 109.32 ? 111 TRP C O   1 
ATOM   8074  C CB  . TRP C 1 103 ? -68.125 72.125  50.175 1.00 93.03  ? 111 TRP C CB  1 
ATOM   8075  C CG  . TRP C 1 103 ? -67.345 72.337  51.446 1.00 105.16 ? 111 TRP C CG  1 
ATOM   8076  C CD1 . TRP C 1 103 ? -67.774 73.038  52.519 1.00 97.68  ? 111 TRP C CD1 1 
ATOM   8077  C CD2 . TRP C 1 103 ? -66.028 71.828  51.784 1.00 116.44 ? 111 TRP C CD2 1 
ATOM   8078  N NE1 . TRP C 1 103 ? -66.819 73.006  53.500 1.00 134.19 ? 111 TRP C NE1 1 
ATOM   8079  C CE2 . TRP C 1 103 ? -65.742 72.266  53.100 1.00 99.26  ? 111 TRP C CE2 1 
ATOM   8080  C CE3 . TRP C 1 103 ? -65.083 71.027  51.118 1.00 120.26 ? 111 TRP C CE3 1 
ATOM   8081  C CZ2 . TRP C 1 103 ? -64.565 71.945  53.775 1.00 84.85  ? 111 TRP C CZ2 1 
ATOM   8082  C CZ3 . TRP C 1 103 ? -63.916 70.710  51.776 1.00 140.54 ? 111 TRP C CZ3 1 
ATOM   8083  C CH2 . TRP C 1 103 ? -63.662 71.170  53.080 1.00 118.58 ? 111 TRP C CH2 1 
ATOM   8084  N N   . GLY C 1 104 ? -67.270 71.950  47.013 1.00 115.29 ? 112 GLY C N   1 
ATOM   8085  C CA  . GLY C 1 104 ? -67.587 71.172  45.831 1.00 116.57 ? 112 GLY C CA  1 
ATOM   8086  C C   . GLY C 1 104 ? -67.105 69.746  46.045 1.00 103.50 ? 112 GLY C C   1 
ATOM   8087  O O   . GLY C 1 104 ? -66.366 69.472  46.973 1.00 108.50 ? 112 GLY C O   1 
ATOM   8088  N N   . VAL C 1 105 ? -67.521 68.844  45.171 1.00 84.79  ? 113 VAL C N   1 
ATOM   8089  C CA  . VAL C 1 105 ? -67.072 67.474  45.294 1.00 80.48  ? 113 VAL C CA  1 
ATOM   8090  C C   . VAL C 1 105 ? -66.916 66.865  43.899 1.00 84.22  ? 113 VAL C C   1 
ATOM   8091  O O   . VAL C 1 105 ? -67.752 67.054  43.040 1.00 107.31 ? 113 VAL C O   1 
ATOM   8092  C CB  . VAL C 1 105 ? -68.072 66.663  46.140 1.00 77.27  ? 113 VAL C CB  1 
ATOM   8093  C CG1 . VAL C 1 105 ? -69.427 66.576  45.463 1.00 74.02  ? 113 VAL C CG1 1 
ATOM   8094  C CG2 . VAL C 1 105 ? -67.620 65.225  46.334 1.00 86.75  ? 113 VAL C CG2 1 
ATOM   8095  N N   . ASN C 1 106 ? -65.844 66.107  43.682 1.00 66.12  ? 114 ASN C N   1 
ATOM   8096  C CA  . ASN C 1 106 ? -65.737 65.308  42.485 1.00 73.71  ? 114 ASN C CA  1 
ATOM   8097  C C   . ASN C 1 106 ? -66.033 63.843  42.847 1.00 85.02  ? 114 ASN C C   1 
ATOM   8098  O O   . ASN C 1 106 ? -65.465 63.332  43.822 1.00 82.49  ? 114 ASN C O   1 
ATOM   8099  C CB  . ASN C 1 106 ? -64.338 65.572  41.980 1.00 81.77  ? 114 ASN C CB  1 
ATOM   8100  C CG  . ASN C 1 106 ? -63.913 64.796  40.758 1.00 102.29 ? 114 ASN C CG  1 
ATOM   8101  O OD1 . ASN C 1 106 ? -64.393 63.705  40.420 1.00 89.20  ? 114 ASN C OD1 1 
ATOM   8102  N ND2 . ASN C 1 106 ? -62.925 65.368  40.089 1.00 121.51 ? 114 ASN C ND2 1 
ATOM   8103  N N   . VAL C 1 107 ? -66.891 63.168  42.068 1.00 57.89  ? 115 VAL C N   1 
ATOM   8104  C CA  . VAL C 1 107 ? -67.263 61.798  42.411 1.00 44.21  ? 115 VAL C CA  1 
ATOM   8105  C C   . VAL C 1 107 ? -66.693 60.800  41.396 1.00 55.81  ? 115 VAL C C   1 
ATOM   8106  O O   . VAL C 1 107 ? -67.187 59.683  41.279 1.00 90.29  ? 115 VAL C O   1 
ATOM   8107  C CB  . VAL C 1 107 ? -68.803 61.605  42.451 1.00 37.60  ? 115 VAL C CB  1 
ATOM   8108  C CG1 . VAL C 1 107 ? -69.474 62.209  43.649 1.00 33.88  ? 115 VAL C CG1 1 
ATOM   8109  C CG2 . VAL C 1 107 ? -69.475 62.164  41.222 1.00 44.10  ? 115 VAL C CG2 1 
ATOM   8110  N N   . GLN C 1 108 ? -65.677 61.162  40.621 1.00 53.42  ? 116 GLN C N   1 
ATOM   8111  C CA  . GLN C 1 108 ? -65.215 60.234  39.593 1.00 54.12  ? 116 GLN C CA  1 
ATOM   8112  C C   . GLN C 1 108 ? -64.067 59.334  40.046 1.00 69.33  ? 116 GLN C C   1 
ATOM   8113  O O   . GLN C 1 108 ? -63.801 58.322  39.392 1.00 70.37  ? 116 GLN C O   1 
ATOM   8114  C CB  . GLN C 1 108 ? -64.650 60.974  38.392 1.00 46.65  ? 116 GLN C CB  1 
ATOM   8115  C CG  . GLN C 1 108 ? -65.741 61.551  37.530 1.00 42.29  ? 116 GLN C CG  1 
ATOM   8116  C CD  . GLN C 1 108 ? -65.173 62.205  36.308 1.00 56.75  ? 116 GLN C CD  1 
ATOM   8117  O OE1 . GLN C 1 108 ? -64.234 61.672  35.627 1.00 53.36  ? 116 GLN C OE1 1 
ATOM   8118  N NE2 . GLN C 1 108 ? -65.952 63.262  36.018 1.00 44.00  ? 116 GLN C NE2 1 
ATOM   8119  N N   . PRO C 1 109 ? -63.305 59.662  41.124 1.00 76.17  ? 117 PRO C N   1 
ATOM   8120  C CA  . PRO C 1 109 ? -62.183 58.812  41.526 1.00 71.97  ? 117 PRO C CA  1 
ATOM   8121  C C   . PRO C 1 109 ? -62.586 57.346  41.480 1.00 74.78  ? 117 PRO C C   1 
ATOM   8122  O O   . PRO C 1 109 ? -63.594 56.947  42.067 1.00 91.93  ? 117 PRO C O   1 
ATOM   8123  C CB  . PRO C 1 109 ? -61.962 59.301  42.947 1.00 72.23  ? 117 PRO C CB  1 
ATOM   8124  C CG  . PRO C 1 109 ? -62.268 60.778  42.877 1.00 84.17  ? 117 PRO C CG  1 
ATOM   8125  C CD  . PRO C 1 109 ? -63.491 60.833  42.002 1.00 82.29  ? 117 PRO C CD  1 
ATOM   8126  N N   . TYR C 1 110 ? -61.756 56.532  40.817 1.00 73.39  ? 118 TYR C N   1 
ATOM   8127  C CA  . TYR C 1 110 ? -62.059 55.118  40.638 1.00 68.48  ? 118 TYR C CA  1 
ATOM   8128  C C   . TYR C 1 110 ? -62.063 54.333  41.957 1.00 78.04  ? 118 TYR C C   1 
ATOM   8129  O O   . TYR C 1 110 ? -62.772 53.337  42.102 1.00 77.19  ? 118 TYR C O   1 
ATOM   8130  C CB  . TYR C 1 110 ? -60.956 54.608  39.740 1.00 56.51  ? 118 TYR C CB  1 
ATOM   8131  C CG  . TYR C 1 110 ? -61.106 55.087  38.314 1.00 71.45  ? 118 TYR C CG  1 
ATOM   8132  C CD1 . TYR C 1 110 ? -62.341 55.432  37.753 1.00 68.34  ? 118 TYR C CD1 1 
ATOM   8133  C CD2 . TYR C 1 110 ? -59.971 55.137  37.515 1.00 105.43 ? 118 TYR C CD2 1 
ATOM   8134  C CE1 . TYR C 1 110 ? -62.406 55.865  36.436 1.00 104.08 ? 118 TYR C CE1 1 
ATOM   8135  C CE2 . TYR C 1 110 ? -60.038 55.529  36.190 1.00 139.06 ? 118 TYR C CE2 1 
ATOM   8136  C CZ  . TYR C 1 110 ? -61.258 55.895  35.655 1.00 124.27 ? 118 TYR C CZ  1 
ATOM   8137  O OH  . TYR C 1 110 ? -61.241 56.285  34.349 1.00 117.57 ? 118 TYR C OH  1 
ATOM   8138  N N   . SER C 1 111 ? -61.265 54.790  42.915 1.00 64.48  ? 119 SER C N   1 
ATOM   8139  C CA  . SER C 1 111 ? -61.230 54.213  44.239 1.00 68.84  ? 119 SER C CA  1 
ATOM   8140  C C   . SER C 1 111 ? -60.594 55.254  45.164 1.00 67.09  ? 119 SER C C   1 
ATOM   8141  O O   . SER C 1 111 ? -60.346 56.392  44.750 1.00 78.24  ? 119 SER C O   1 
ATOM   8142  C CB  . SER C 1 111 ? -60.460 52.898  44.214 1.00 73.70  ? 119 SER C CB  1 
ATOM   8143  O OG  . SER C 1 111 ? -60.751 52.115  45.375 1.00 73.86  ? 119 SER C OG  1 
ATOM   8144  N N   . GLY C 1 112 ? -60.270 54.849  46.394 1.00 51.68  ? 120 GLY C N   1 
ATOM   8145  C CA  . GLY C 1 112 ? -59.648 55.750  47.333 1.00 57.94  ? 120 GLY C CA  1 
ATOM   8146  C C   . GLY C 1 112 ? -58.277 56.241  46.858 1.00 69.05  ? 120 GLY C C   1 
ATOM   8147  O O   . GLY C 1 112 ? -58.026 57.455  46.756 1.00 69.62  ? 120 GLY C O   1 
ATOM   8148  N N   . SER C 1 113 ? -57.359 55.292  46.631 1.00 55.94  ? 121 SER C N   1 
ATOM   8149  C CA  . SER C 1 113 ? -55.998 55.693  46.330 1.00 58.01  ? 121 SER C CA  1 
ATOM   8150  C C   . SER C 1 113 ? -55.981 56.619  45.108 1.00 67.18  ? 121 SER C C   1 
ATOM   8151  O O   . SER C 1 113 ? -55.256 57.612  45.098 1.00 72.26  ? 121 SER C O   1 
ATOM   8152  C CB  . SER C 1 113 ? -55.078 54.521  46.159 1.00 65.79  ? 121 SER C CB  1 
ATOM   8153  O OG  . SER C 1 113 ? -55.316 53.491  47.100 1.00 84.46  ? 121 SER C OG  1 
ATOM   8154  N N   . PRO C 1 114 ? -56.702 56.333  43.987 1.00 58.51  ? 122 PRO C N   1 
ATOM   8155  C CA  . PRO C 1 114 ? -56.885 57.327  42.917 1.00 61.20  ? 122 PRO C CA  1 
ATOM   8156  C C   . PRO C 1 114 ? -57.281 58.723  43.385 1.00 69.54  ? 122 PRO C C   1 
ATOM   8157  O O   . PRO C 1 114 ? -56.743 59.726  42.912 1.00 52.48  ? 122 PRO C O   1 
ATOM   8158  C CB  . PRO C 1 114 ? -57.967 56.754  42.087 1.00 46.64  ? 122 PRO C CB  1 
ATOM   8159  C CG  . PRO C 1 114 ? -57.674 55.272  42.256 1.00 64.64  ? 122 PRO C CG  1 
ATOM   8160  C CD  . PRO C 1 114 ? -57.343 55.052  43.703 1.00 52.48  ? 122 PRO C CD  1 
ATOM   8161  N N   . ALA C 1 115 ? -58.180 58.789  44.369 1.00 75.92  ? 123 ALA C N   1 
ATOM   8162  C CA  . ALA C 1 115 ? -58.652 60.092  44.806 1.00 87.00  ? 123 ALA C CA  1 
ATOM   8163  C C   . ALA C 1 115 ? -57.504 60.898  45.420 1.00 89.57  ? 123 ALA C C   1 
ATOM   8164  O O   . ALA C 1 115 ? -57.310 62.080  45.084 1.00 81.88  ? 123 ALA C O   1 
ATOM   8165  C CB  . ALA C 1 115 ? -59.848 59.927  45.719 1.00 57.77  ? 123 ALA C CB  1 
ATOM   8166  N N   . ASN C 1 116 ? -56.718 60.233  46.281 1.00 63.48  ? 124 ASN C N   1 
ATOM   8167  C CA  . ASN C 1 116 ? -55.671 60.953  46.987 1.00 83.94  ? 124 ASN C CA  1 
ATOM   8168  C C   . ASN C 1 116 ? -54.641 61.403  45.947 1.00 79.78  ? 124 ASN C C   1 
ATOM   8169  O O   . ASN C 1 116 ? -54.157 62.549  45.952 1.00 54.36  ? 124 ASN C O   1 
ATOM   8170  C CB  . ASN C 1 116 ? -54.999 60.079  48.041 1.00 80.93  ? 124 ASN C CB  1 
ATOM   8171  C CG  . ASN C 1 116 ? -55.859 59.696  49.202 1.00 72.10  ? 124 ASN C CG  1 
ATOM   8172  O OD1 . ASN C 1 116 ? -56.955 60.239  49.361 1.00 83.14  ? 124 ASN C OD1 1 
ATOM   8173  N ND2 . ASN C 1 116 ? -55.349 58.776  50.000 1.00 72.84  ? 124 ASN C ND2 1 
ATOM   8174  N N   . PHE C 1 117 ? -54.299 60.473  45.047 1.00 64.75  ? 125 PHE C N   1 
ATOM   8175  C CA  . PHE C 1 117 ? -53.239 60.751  44.099 1.00 76.41  ? 125 PHE C CA  1 
ATOM   8176  C C   . PHE C 1 117 ? -53.653 61.975  43.288 1.00 79.07  ? 125 PHE C C   1 
ATOM   8177  O O   . PHE C 1 117 ? -52.803 62.804  42.934 1.00 103.05 ? 125 PHE C O   1 
ATOM   8178  C CB  . PHE C 1 117 ? -52.874 59.513  43.269 1.00 72.02  ? 125 PHE C CB  1 
ATOM   8179  C CG  . PHE C 1 117 ? -51.552 59.755  42.560 1.00 70.77  ? 125 PHE C CG  1 
ATOM   8180  C CD1 . PHE C 1 117 ? -50.342 59.449  43.201 1.00 81.91  ? 125 PHE C CD1 1 
ATOM   8181  C CD2 . PHE C 1 117 ? -51.507 60.376  41.305 1.00 69.79  ? 125 PHE C CD2 1 
ATOM   8182  C CE1 . PHE C 1 117 ? -49.117 59.708  42.580 1.00 84.26  ? 125 PHE C CE1 1 
ATOM   8183  C CE2 . PHE C 1 117 ? -50.281 60.637  40.693 1.00 86.10  ? 125 PHE C CE2 1 
ATOM   8184  C CZ  . PHE C 1 117 ? -49.092 60.293  41.329 1.00 100.87 ? 125 PHE C CZ  1 
ATOM   8185  N N   . ALA C 1 118 ? -54.969 62.056  43.006 1.00 53.85  ? 126 ALA C N   1 
ATOM   8186  C CA  . ALA C 1 118 ? -55.512 63.170  42.236 1.00 79.42  ? 126 ALA C CA  1 
ATOM   8187  C C   . ALA C 1 118 ? -55.305 64.498  42.974 1.00 88.20  ? 126 ALA C C   1 
ATOM   8188  O O   . ALA C 1 118 ? -54.889 65.516  42.388 1.00 76.70  ? 126 ALA C O   1 
ATOM   8189  C CB  . ALA C 1 118 ? -56.964 62.931  41.936 1.00 63.84  ? 126 ALA C CB  1 
ATOM   8190  N N   . VAL C 1 119 ? -55.595 64.476  44.281 1.00 56.59  ? 127 VAL C N   1 
ATOM   8191  C CA  . VAL C 1 119 ? -55.437 65.704  45.035 1.00 60.41  ? 127 VAL C CA  1 
ATOM   8192  C C   . VAL C 1 119 ? -53.963 66.125  45.068 1.00 76.83  ? 127 VAL C C   1 
ATOM   8193  O O   . VAL C 1 119 ? -53.695 67.340  44.988 1.00 62.37  ? 127 VAL C O   1 
ATOM   8194  C CB  . VAL C 1 119 ? -56.053 65.580  46.447 1.00 64.82  ? 127 VAL C CB  1 
ATOM   8195  C CG1 . VAL C 1 119 ? -55.730 66.749  47.370 1.00 48.75  ? 127 VAL C CG1 1 
ATOM   8196  C CG2 . VAL C 1 119 ? -57.547 65.395  46.362 1.00 72.52  ? 127 VAL C CG2 1 
ATOM   8197  N N   . TYR C 1 120 ? -53.026 65.151  45.227 1.00 66.99  ? 128 TYR C N   1 
ATOM   8198  C CA  . TYR C 1 120 ? -51.606 65.485  45.287 1.00 62.35  ? 128 TYR C CA  1 
ATOM   8199  C C   . TYR C 1 120 ? -51.170 66.056  43.943 1.00 68.86  ? 128 TYR C C   1 
ATOM   8200  O O   . TYR C 1 120 ? -50.431 67.033  43.884 1.00 71.23  ? 128 TYR C O   1 
ATOM   8201  C CB  . TYR C 1 120 ? -50.747 64.258  45.583 1.00 58.94  ? 128 TYR C CB  1 
ATOM   8202  C CG  . TYR C 1 120 ? -51.182 63.426  46.782 1.00 77.90  ? 128 TYR C CG  1 
ATOM   8203  C CD1 . TYR C 1 120 ? -51.506 64.024  47.990 1.00 105.55 ? 128 TYR C CD1 1 
ATOM   8204  C CD2 . TYR C 1 120 ? -51.210 62.035  46.735 1.00 84.35  ? 128 TYR C CD2 1 
ATOM   8205  C CE1 . TYR C 1 120 ? -51.847 63.278  49.109 1.00 86.12  ? 128 TYR C CE1 1 
ATOM   8206  C CE2 . TYR C 1 120 ? -51.554 61.276  47.845 1.00 86.20  ? 128 TYR C CE2 1 
ATOM   8207  C CZ  . TYR C 1 120 ? -51.921 61.906  49.016 1.00 84.88  ? 128 TYR C CZ  1 
ATOM   8208  O OH  . TYR C 1 120 ? -52.298 61.144  50.072 1.00 108.06 ? 128 TYR C OH  1 
ATOM   8209  N N   . THR C 1 121 ? -51.703 65.479  42.861 1.00 56.68  ? 129 THR C N   1 
ATOM   8210  C CA  . THR C 1 121 ? -51.422 65.969  41.519 1.00 59.65  ? 129 THR C CA  1 
ATOM   8211  C C   . THR C 1 121 ? -51.892 67.409  41.342 1.00 59.34  ? 129 THR C C   1 
ATOM   8212  O O   . THR C 1 121 ? -51.161 68.208  40.780 1.00 54.85  ? 129 THR C O   1 
ATOM   8213  C CB  . THR C 1 121 ? -51.971 65.100  40.402 1.00 55.59  ? 129 THR C CB  1 
ATOM   8214  O OG1 . THR C 1 121 ? -51.401 63.801  40.575 1.00 94.30  ? 129 THR C OG1 1 
ATOM   8215  C CG2 . THR C 1 121 ? -51.399 65.637  39.103 1.00 36.07  ? 129 THR C CG2 1 
ATOM   8216  N N   . ALA C 1 122 ? -53.092 67.724  41.846 1.00 62.94  ? 130 ALA C N   1 
ATOM   8217  C CA  . ALA C 1 122 ? -53.679 69.060  41.685 1.00 68.27  ? 130 ALA C CA  1 
ATOM   8218  C C   . ALA C 1 122 ? -52.998 70.111  42.575 1.00 78.13  ? 130 ALA C C   1 
ATOM   8219  O O   . ALA C 1 122 ? -52.848 71.258  42.166 1.00 55.47  ? 130 ALA C O   1 
ATOM   8220  C CB  . ALA C 1 122 ? -55.138 69.051  41.969 1.00 50.46  ? 130 ALA C CB  1 
ATOM   8221  N N   . LEU C 1 123 ? -52.605 69.736  43.799 1.00 76.31  ? 131 LEU C N   1 
ATOM   8222  C CA  . LEU C 1 123 ? -52.197 70.758  44.747 1.00 69.33  ? 131 LEU C CA  1 
ATOM   8223  C C   . LEU C 1 123 ? -50.706 70.683  45.043 1.00 80.30  ? 131 LEU C C   1 
ATOM   8224  O O   . LEU C 1 123 ? -50.126 71.704  45.392 1.00 94.43  ? 131 LEU C O   1 
ATOM   8225  C CB  . LEU C 1 123 ? -52.995 70.738  46.042 1.00 48.20  ? 131 LEU C CB  1 
ATOM   8226  C CG  . LEU C 1 123 ? -54.506 70.636  45.852 1.00 59.12  ? 131 LEU C CG  1 
ATOM   8227  C CD1 . LEU C 1 123 ? -55.147 70.556  47.260 1.00 46.52  ? 131 LEU C CD1 1 
ATOM   8228  C CD2 . LEU C 1 123 ? -54.985 71.793  44.972 1.00 59.19  ? 131 LEU C CD2 1 
ATOM   8229  N N   . VAL C 1 124 ? -50.085 69.510  44.902 1.00 85.41  ? 132 VAL C N   1 
ATOM   8230  C CA  . VAL C 1 124 ? -48.716 69.391  45.382 1.00 80.41  ? 132 VAL C CA  1 
ATOM   8231  C C   . VAL C 1 124 ? -47.746 69.532  44.219 1.00 98.26  ? 132 VAL C C   1 
ATOM   8232  O O   . VAL C 1 124 ? -46.775 70.282  44.353 1.00 93.54  ? 132 VAL C O   1 
ATOM   8233  C CB  . VAL C 1 124 ? -48.476 68.084  46.150 1.00 86.74  ? 132 VAL C CB  1 
ATOM   8234  C CG1 . VAL C 1 124 ? -47.036 67.968  46.628 1.00 114.81 ? 132 VAL C CG1 1 
ATOM   8235  C CG2 . VAL C 1 124 ? -49.436 67.974  47.319 1.00 97.95  ? 132 VAL C CG2 1 
ATOM   8236  N N   . GLU C 1 125 ? -48.104 68.875  43.093 1.00 83.56  ? 133 GLU C N   1 
ATOM   8237  C CA  . GLU C 1 125 ? -47.281 68.710  41.907 1.00 73.06  ? 133 GLU C CA  1 
ATOM   8238  C C   . GLU C 1 125 ? -46.008 67.930  42.223 1.00 84.23  ? 133 GLU C C   1 
ATOM   8239  O O   . GLU C 1 125 ? -45.580 67.825  43.374 1.00 85.63  ? 133 GLU C O   1 
ATOM   8240  C CB  . GLU C 1 125 ? -47.010 70.053  41.225 1.00 81.56  ? 133 GLU C CB  1 
ATOM   8241  C CG  . GLU C 1 125 ? -48.339 70.686  40.851 1.00 95.09  ? 133 GLU C CG  1 
ATOM   8242  C CD  . GLU C 1 125 ? -48.479 72.183  40.896 1.00 97.45  ? 133 GLU C CD  1 
ATOM   8243  O OE1 . GLU C 1 125 ? -47.590 72.826  40.285 1.00 86.81  ? 133 GLU C OE1 1 
ATOM   8244  O OE2 . GLU C 1 125 ? -49.473 72.626  41.561 1.00 77.58  ? 133 GLU C OE2 1 
ATOM   8245  N N   . PRO C 1 126 ? -45.359 67.365  41.180 1.00 74.19  ? 134 PRO C N   1 
ATOM   8246  C CA  . PRO C 1 126 ? -44.173 66.521  41.319 1.00 67.49  ? 134 PRO C CA  1 
ATOM   8247  C C   . PRO C 1 126 ? -43.107 67.082  42.236 1.00 71.13  ? 134 PRO C C   1 
ATOM   8248  O O   . PRO C 1 126 ? -42.859 68.268  42.229 1.00 88.20  ? 134 PRO C O   1 
ATOM   8249  C CB  . PRO C 1 126 ? -43.714 66.528  39.889 1.00 55.46  ? 134 PRO C CB  1 
ATOM   8250  C CG  . PRO C 1 126 ? -45.043 66.285  39.217 1.00 56.69  ? 134 PRO C CG  1 
ATOM   8251  C CD  . PRO C 1 126 ? -45.753 67.489  39.780 1.00 68.93  ? 134 PRO C CD  1 
ATOM   8252  N N   . HIS C 1 127 ? -42.611 66.217  43.109 1.00 71.28  ? 135 HIS C N   1 
ATOM   8253  C CA  . HIS C 1 127 ? -41.545 66.530  44.035 1.00 58.10  ? 135 HIS C CA  1 
ATOM   8254  C C   . HIS C 1 127 ? -42.033 67.386  45.218 1.00 60.36  ? 135 HIS C C   1 
ATOM   8255  O O   . HIS C 1 127 ? -41.221 67.707  46.123 1.00 58.01  ? 135 HIS C O   1 
ATOM   8256  C CB  . HIS C 1 127 ? -40.339 67.075  43.264 1.00 58.76  ? 135 HIS C CB  1 
ATOM   8257  C CG  . HIS C 1 127 ? -39.746 66.101  42.331 1.00 78.93  ? 135 HIS C CG  1 
ATOM   8258  N ND1 . HIS C 1 127 ? -38.984 65.044  42.802 1.00 90.20  ? 135 HIS C ND1 1 
ATOM   8259  C CD2 . HIS C 1 127 ? -39.766 66.018  40.975 1.00 66.06  ? 135 HIS C CD2 1 
ATOM   8260  C CE1 . HIS C 1 127 ? -38.547 64.331  41.764 1.00 97.61  ? 135 HIS C CE1 1 
ATOM   8261  N NE2 . HIS C 1 127 ? -38.975 64.926  40.635 1.00 88.77  ? 135 HIS C NE2 1 
ATOM   8262  N N   . GLY C 1 128 ? -43.340 67.737  45.217 1.00 51.78  ? 136 GLY C N   1 
ATOM   8263  C CA  . GLY C 1 128 ? -43.869 68.552  46.308 1.00 60.97  ? 136 GLY C CA  1 
ATOM   8264  C C   . GLY C 1 128 ? -43.843 67.760  47.610 1.00 59.95  ? 136 GLY C C   1 
ATOM   8265  O O   . GLY C 1 128 ? -43.906 66.525  47.570 1.00 68.52  ? 136 GLY C O   1 
ATOM   8266  N N   . ARG C 1 129 ? -43.713 68.447  48.748 1.00 62.56  ? 137 ARG C N   1 
ATOM   8267  C CA  . ARG C 1 129 ? -43.526 67.676  49.976 1.00 72.30  ? 137 ARG C CA  1 
ATOM   8268  C C   . ARG C 1 129 ? -44.860 67.341  50.641 1.00 76.02  ? 137 ARG C C   1 
ATOM   8269  O O   . ARG C 1 129 ? -45.715 68.221  50.838 1.00 82.62  ? 137 ARG C O   1 
ATOM   8270  C CB  . ARG C 1 129 ? -42.547 68.372  50.921 1.00 66.95  ? 137 ARG C CB  1 
ATOM   8271  C CG  . ARG C 1 129 ? -41.168 68.173  50.324 1.00 73.87  ? 137 ARG C CG  1 
ATOM   8272  C CD  . ARG C 1 129 ? -40.150 69.235  50.646 1.00 82.99  ? 137 ARG C CD  1 
ATOM   8273  N NE  . ARG C 1 129 ? -39.168 68.915  51.679 1.00 65.88  ? 137 ARG C NE  1 
ATOM   8274  C CZ  . ARG C 1 129 ? -37.855 69.018  51.484 1.00 78.56  ? 137 ARG C CZ  1 
ATOM   8275  N NH1 . ARG C 1 129 ? -37.161 69.484  52.512 1.00 87.64  ? 137 ARG C NH1 1 
ATOM   8276  N NH2 . ARG C 1 129 ? -37.263 68.806  50.303 1.00 62.37  ? 137 ARG C NH2 1 
ATOM   8277  N N   . ILE C 1 130 ? -45.020 66.066  51.019 1.00 59.32  ? 138 ILE C N   1 
ATOM   8278  C CA  . ILE C 1 130 ? -46.242 65.655  51.698 1.00 53.24  ? 138 ILE C CA  1 
ATOM   8279  C C   . ILE C 1 130 ? -45.887 65.051  53.064 1.00 61.77  ? 138 ILE C C   1 
ATOM   8280  O O   . ILE C 1 130 ? -44.852 64.382  53.164 1.00 67.43  ? 138 ILE C O   1 
ATOM   8281  C CB  . ILE C 1 130 ? -46.952 64.654  50.790 1.00 47.25  ? 138 ILE C CB  1 
ATOM   8282  C CG1 . ILE C 1 130 ? -47.329 65.290  49.441 1.00 47.99  ? 138 ILE C CG1 1 
ATOM   8283  C CG2 . ILE C 1 130 ? -48.115 63.978  51.513 1.00 55.73  ? 138 ILE C CG2 1 
ATOM   8284  C CD1 . ILE C 1 130 ? -47.985 64.337  48.455 1.00 68.07  ? 138 ILE C CD1 1 
ATOM   8285  N N   . MET C 1 131 ? -46.690 65.322  54.108 1.00 54.90  ? 139 MET C N   1 
ATOM   8286  C CA  . MET C 1 131 ? -46.532 64.632  55.388 1.00 54.48  ? 139 MET C CA  1 
ATOM   8287  C C   . MET C 1 131 ? -47.847 63.965  55.771 1.00 68.01  ? 139 MET C C   1 
ATOM   8288  O O   . MET C 1 131 ? -48.923 64.576  55.732 1.00 71.07  ? 139 MET C O   1 
ATOM   8289  C CB  . MET C 1 131 ? -46.105 65.524  56.560 1.00 53.71  ? 139 MET C CB  1 
ATOM   8290  C CG  . MET C 1 131 ? -44.691 66.062  56.471 1.00 63.89  ? 139 MET C CG  1 
ATOM   8291  S SD  . MET C 1 131 ? -44.295 67.217  57.822 1.00 80.98  ? 139 MET C SD  1 
ATOM   8292  C CE  . MET C 1 131 ? -43.813 66.178  59.202 1.00 54.17  ? 139 MET C CE  1 
ATOM   8293  N N   . GLY C 1 132 ? -47.737 62.688  56.139 1.00 77.09  ? 140 GLY C N   1 
ATOM   8294  C CA  . GLY C 1 132 ? -48.854 61.906  56.654 1.00 95.34  ? 140 GLY C CA  1 
ATOM   8295  C C   . GLY C 1 132 ? -48.405 61.028  57.820 1.00 83.20  ? 140 GLY C C   1 
ATOM   8296  O O   . GLY C 1 132 ? -47.201 60.868  58.064 1.00 84.54  ? 140 GLY C O   1 
ATOM   8297  N N   . LEU C 1 133 ? -49.368 60.417  58.507 1.00 64.42  ? 141 LEU C N   1 
ATOM   8298  C CA  . LEU C 1 133 ? -48.998 59.530  59.607 1.00 65.77  ? 141 LEU C CA  1 
ATOM   8299  C C   . LEU C 1 133 ? -48.174 58.348  59.094 1.00 62.81  ? 141 LEU C C   1 
ATOM   8300  O O   . LEU C 1 133 ? -48.605 57.713  58.169 1.00 48.53  ? 141 LEU C O   1 
ATOM   8301  C CB  . LEU C 1 133 ? -50.306 59.016  60.215 1.00 69.06  ? 141 LEU C CB  1 
ATOM   8302  C CG  . LEU C 1 133 ? -50.180 58.133  61.451 1.00 54.47  ? 141 LEU C CG  1 
ATOM   8303  C CD1 . LEU C 1 133 ? -49.387 58.847  62.556 1.00 60.79  ? 141 LEU C CD1 1 
ATOM   8304  C CD2 . LEU C 1 133 ? -51.591 57.795  61.883 1.00 65.89  ? 141 LEU C CD2 1 
ATOM   8305  N N   . ASP C 1 134 ? -47.039 57.989  59.716 1.00 96.70  ? 142 ASP C N   1 
ATOM   8306  C CA  . ASP C 1 134 ? -46.239 56.845  59.267 1.00 85.37  ? 142 ASP C CA  1 
ATOM   8307  C C   . ASP C 1 134 ? -47.156 55.630  59.174 1.00 85.22  ? 142 ASP C C   1 
ATOM   8308  O O   . ASP C 1 134 ? -48.026 55.462  60.020 1.00 111.02 ? 142 ASP C O   1 
ATOM   8309  C CB  . ASP C 1 134 ? -45.114 56.457  60.233 1.00 85.19  ? 142 ASP C CB  1 
ATOM   8310  C CG  . ASP C 1 134 ? -43.978 55.662  59.575 1.00 102.63 ? 142 ASP C CG  1 
ATOM   8311  O OD1 . ASP C 1 134 ? -44.099 55.384  58.379 1.00 105.66 ? 142 ASP C OD1 1 
ATOM   8312  O OD2 . ASP C 1 134 ? -42.987 55.260  60.217 1.00 98.36  ? 142 ASP C OD2 1 
ATOM   8313  N N   . LEU C 1 135 ? -46.969 54.790  58.152 1.00 78.31  ? 143 LEU C N   1 
ATOM   8314  C CA  . LEU C 1 135 ? -47.804 53.607  57.959 1.00 80.73  ? 143 LEU C CA  1 
ATOM   8315  C C   . LEU C 1 135 ? -47.852 52.696  59.208 1.00 72.46  ? 143 LEU C C   1 
ATOM   8316  O O   . LEU C 1 135 ? -48.930 52.413  59.742 1.00 44.70  ? 143 LEU C O   1 
ATOM   8317  C CB  . LEU C 1 135 ? -47.211 52.892  56.746 1.00 75.56  ? 143 LEU C CB  1 
ATOM   8318  C CG  . LEU C 1 135 ? -48.017 51.714  56.219 1.00 92.25  ? 143 LEU C CG  1 
ATOM   8319  C CD1 . LEU C 1 135 ? -49.428 52.116  55.860 1.00 96.15  ? 143 LEU C CD1 1 
ATOM   8320  C CD2 . LEU C 1 135 ? -47.333 51.277  54.951 1.00 101.85 ? 143 LEU C CD2 1 
ATOM   8321  N N   . PRO C 1 136 ? -46.711 52.230  59.776 1.00 70.48  ? 144 PRO C N   1 
ATOM   8322  C CA  . PRO C 1 136 ? -46.722 51.396  60.978 1.00 75.97  ? 144 PRO C CA  1 
ATOM   8323  C C   . PRO C 1 136 ? -47.396 52.076  62.169 1.00 65.89  ? 144 PRO C C   1 
ATOM   8324  O O   . PRO C 1 136 ? -47.773 51.395  63.114 1.00 73.66  ? 144 PRO C O   1 
ATOM   8325  C CB  . PRO C 1 136 ? -45.230 51.121  61.289 1.00 73.34  ? 144 PRO C CB  1 
ATOM   8326  C CG  . PRO C 1 136 ? -44.571 52.347  60.667 1.00 100.88 ? 144 PRO C CG  1 
ATOM   8327  C CD  . PRO C 1 136 ? -45.343 52.531  59.351 1.00 88.42  ? 144 PRO C CD  1 
ATOM   8328  N N   . ASP C 1 137 ? -47.542 53.400  62.118 1.00 57.99  ? 145 ASP C N   1 
ATOM   8329  C CA  . ASP C 1 137 ? -48.206 54.119  63.191 1.00 73.61  ? 145 ASP C CA  1 
ATOM   8330  C C   . ASP C 1 137 ? -49.702 54.317  62.878 1.00 84.81  ? 145 ASP C C   1 
ATOM   8331  O O   . ASP C 1 137 ? -50.372 55.068  63.602 1.00 67.74  ? 145 ASP C O   1 
ATOM   8332  C CB  . ASP C 1 137 ? -47.532 55.464  63.442 1.00 84.68  ? 145 ASP C CB  1 
ATOM   8333  C CG  . ASP C 1 137 ? -46.116 55.413  64.001 1.00 100.53 ? 145 ASP C CG  1 
ATOM   8334  O OD1 . ASP C 1 137 ? -45.579 54.296  64.186 1.00 98.41  ? 145 ASP C OD1 1 
ATOM   8335  O OD2 . ASP C 1 137 ? -45.555 56.492  64.269 1.00 89.15  ? 145 ASP C OD2 1 
ATOM   8336  N N   . GLY C 1 138 ? -50.231 53.678  61.802 1.00 61.67  ? 146 GLY C N   1 
ATOM   8337  C CA  . GLY C 1 138 ? -51.657 53.711  61.494 1.00 80.04  ? 146 GLY C CA  1 
ATOM   8338  C C   . GLY C 1 138 ? -52.016 54.587  60.288 1.00 102.95 ? 146 GLY C C   1 
ATOM   8339  O O   . GLY C 1 138 ? -53.203 54.840  60.018 1.00 93.41  ? 146 GLY C O   1 
ATOM   8340  N N   . GLY C 1 139 ? -50.986 54.987  59.528 1.00 96.44  ? 147 GLY C N   1 
ATOM   8341  C CA  . GLY C 1 139 ? -51.192 55.750  58.305 1.00 88.11  ? 147 GLY C CA  1 
ATOM   8342  C C   . GLY C 1 139 ? -51.676 54.861  57.170 1.00 84.43  ? 147 GLY C C   1 
ATOM   8343  O O   . GLY C 1 139 ? -51.877 53.660  57.399 1.00 98.10  ? 147 GLY C O   1 
ATOM   8344  N N   . HIS C 1 140 ? -51.888 55.447  55.972 1.00 68.16  ? 148 HIS C N   1 
ATOM   8345  C CA  . HIS C 1 140 ? -52.200 54.628  54.802 1.00 81.19  ? 148 HIS C CA  1 
ATOM   8346  C C   . HIS C 1 140 ? -51.127 54.784  53.736 1.00 84.34  ? 148 HIS C C   1 
ATOM   8347  O O   . HIS C 1 140 ? -50.560 55.851  53.629 1.00 58.18  ? 148 HIS C O   1 
ATOM   8348  C CB  . HIS C 1 140 ? -53.574 54.904  54.193 1.00 73.71  ? 148 HIS C CB  1 
ATOM   8349  C CG  . HIS C 1 140 ? -53.952 53.916  53.138 1.00 74.81  ? 148 HIS C CG  1 
ATOM   8350  N ND1 . HIS C 1 140 ? -54.286 54.235  51.832 1.00 60.11  ? 148 HIS C ND1 1 
ATOM   8351  C CD2 . HIS C 1 140 ? -54.212 52.608  53.243 1.00 92.78  ? 148 HIS C CD2 1 
ATOM   8352  C CE1 . HIS C 1 140 ? -54.686 53.167  51.171 1.00 60.73  ? 148 HIS C CE1 1 
ATOM   8353  N NE2 . HIS C 1 140 ? -54.613 52.150  51.995 1.00 100.22 ? 148 HIS C NE2 1 
ATOM   8354  N N   . LEU C 1 141 ? -50.866 53.734  52.935 1.00 89.11  ? 149 LEU C N   1 
ATOM   8355  C CA  . LEU C 1 141 ? -49.811 53.772  51.913 1.00 77.90  ? 149 LEU C CA  1 
ATOM   8356  C C   . LEU C 1 141 ? -49.903 55.049  51.082 1.00 77.27  ? 149 LEU C C   1 
ATOM   8357  O O   . LEU C 1 141 ? -48.897 55.725  50.903 1.00 107.71 ? 149 LEU C O   1 
ATOM   8358  C CB  . LEU C 1 141 ? -49.723 52.597  50.954 1.00 62.33  ? 149 LEU C CB  1 
ATOM   8359  C CG  . LEU C 1 141 ? -49.790 51.204  51.580 1.00 65.08  ? 149 LEU C CG  1 
ATOM   8360  C CD1 . LEU C 1 141 ? -50.950 50.950  52.695 1.00 40.82  ? 149 LEU C CD1 1 
ATOM   8361  C CD2 . LEU C 1 141 ? -49.764 50.250  50.282 1.00 52.19  ? 149 LEU C CD2 1 
ATOM   8362  N N   . THR C 1 142 ? -51.111 55.381  50.596 1.00 59.45  ? 150 THR C N   1 
ATOM   8363  C CA  . THR C 1 142 ? -51.268 56.576  49.766 1.00 78.43  ? 150 THR C CA  1 
ATOM   8364  C C   . THR C 1 142 ? -50.906 57.890  50.483 1.00 79.88  ? 150 THR C C   1 
ATOM   8365  O O   . THR C 1 142 ? -50.940 58.942  49.837 1.00 74.88  ? 150 THR C O   1 
ATOM   8366  C CB  . THR C 1 142 ? -52.688 56.632  49.230 1.00 78.22  ? 150 THR C CB  1 
ATOM   8367  O OG1 . THR C 1 142 ? -53.355 56.501  50.486 1.00 70.87  ? 150 THR C OG1 1 
ATOM   8368  C CG2 . THR C 1 142 ? -52.922 55.512  48.236 1.00 63.65  ? 150 THR C CG2 1 
ATOM   8369  N N   . HIS C 1 143 ? -50.595 57.841  51.798 1.00 55.51  ? 151 HIS C N   1 
ATOM   8370  C CA  . HIS C 1 143 ? -50.215 59.016  52.558 1.00 55.35  ? 151 HIS C CA  1 
ATOM   8371  C C   . HIS C 1 143 ? -48.691 59.081  52.623 1.00 54.33  ? 151 HIS C C   1 
ATOM   8372  O O   . HIS C 1 143 ? -48.072 59.668  53.532 1.00 50.01  ? 151 HIS C O   1 
ATOM   8373  C CB  . HIS C 1 143 ? -50.779 58.934  53.982 1.00 74.04  ? 151 HIS C CB  1 
ATOM   8374  C CG  . HIS C 1 143 ? -52.250 58.808  54.084 1.00 91.12  ? 151 HIS C CG  1 
ATOM   8375  N ND1 . HIS C 1 143 ? -52.873 58.644  55.302 1.00 110.47 ? 151 HIS C ND1 1 
ATOM   8376  C CD2 . HIS C 1 143 ? -53.222 58.858  53.140 1.00 94.41  ? 151 HIS C CD2 1 
ATOM   8377  C CE1 . HIS C 1 143 ? -54.191 58.580  55.082 1.00 127.06 ? 151 HIS C CE1 1 
ATOM   8378  N NE2 . HIS C 1 143 ? -54.426 58.666  53.768 1.00 82.68  ? 151 HIS C NE2 1 
ATOM   8379  N N   . GLY C 1 144 ? -48.055 58.368  51.700 1.00 58.83  ? 152 GLY C N   1 
ATOM   8380  C CA  . GLY C 1 144 ? -46.602 58.362  51.585 1.00 57.63  ? 152 GLY C CA  1 
ATOM   8381  C C   . GLY C 1 144 ? -46.071 57.101  52.256 1.00 70.45  ? 152 GLY C C   1 
ATOM   8382  O O   . GLY C 1 144 ? -46.644 56.678  53.247 1.00 61.77  ? 152 GLY C O   1 
ATOM   8383  N N   . PHE C 1 145 ? -45.042 56.469  51.695 1.00 83.35  ? 153 PHE C N   1 
ATOM   8384  C CA  . PHE C 1 145 ? -44.364 55.387  52.390 1.00 76.02  ? 153 PHE C CA  1 
ATOM   8385  C C   . PHE C 1 145 ? -43.111 55.027  51.612 1.00 78.54  ? 153 PHE C C   1 
ATOM   8386  O O   . PHE C 1 145 ? -43.182 54.677  50.413 1.00 61.34  ? 153 PHE C O   1 
ATOM   8387  C CB  . PHE C 1 145 ? -45.298 54.177  52.491 1.00 91.53  ? 153 PHE C CB  1 
ATOM   8388  C CG  . PHE C 1 145 ? -44.649 52.957  53.117 1.00 99.69  ? 153 PHE C CG  1 
ATOM   8389  C CD1 . PHE C 1 145 ? -44.175 53.013  54.429 1.00 85.63  ? 153 PHE C CD1 1 
ATOM   8390  C CD2 . PHE C 1 145 ? -44.592 51.736  52.443 1.00 91.09  ? 153 PHE C CD2 1 
ATOM   8391  C CE1 . PHE C 1 145 ? -43.593 51.906  55.029 1.00 69.73  ? 153 PHE C CE1 1 
ATOM   8392  C CE2 . PHE C 1 145 ? -43.981 50.641  53.037 1.00 82.58  ? 153 PHE C CE2 1 
ATOM   8393  C CZ  . PHE C 1 145 ? -43.490 50.724  54.329 1.00 69.30  ? 153 PHE C CZ  1 
ATOM   8394  N N   . MET C 1 146 ? -41.987 55.137  52.326 1.00 66.86  ? 154 MET C N   1 
ATOM   8395  C CA  . MET C 1 146 ? -40.715 54.863  51.670 1.00 97.12  ? 154 MET C CA  1 
ATOM   8396  C C   . MET C 1 146 ? -39.704 54.442  52.725 1.00 93.69  ? 154 MET C C   1 
ATOM   8397  O O   . MET C 1 146 ? -39.714 54.967  53.832 1.00 105.56 ? 154 MET C O   1 
ATOM   8398  C CB  . MET C 1 146 ? -40.148 56.059  50.878 1.00 91.58  ? 154 MET C CB  1 
ATOM   8399  C CG  . MET C 1 146 ? -39.848 57.291  51.715 1.00 69.86  ? 154 MET C CG  1 
ATOM   8400  S SD  . MET C 1 146 ? -39.183 58.622  50.695 1.00 96.36  ? 154 MET C SD  1 
ATOM   8401  C CE  . MET C 1 146 ? -37.447 58.272  51.041 1.00 85.37  ? 154 MET C CE  1 
ATOM   8402  N N   . THR C 1 147 ? -38.837 53.501  52.339 1.00 78.66  ? 155 THR C N   1 
ATOM   8403  C CA  . THR C 1 147 ? -37.834 52.925  53.211 1.00 94.84  ? 155 THR C CA  1 
ATOM   8404  C C   . THR C 1 147 ? -36.467 53.412  52.720 1.00 110.87 ? 155 THR C C   1 
ATOM   8405  O O   . THR C 1 147 ? -36.379 54.023  51.655 1.00 109.09 ? 155 THR C O   1 
ATOM   8406  C CB  . THR C 1 147 ? -38.008 51.409  53.115 1.00 108.99 ? 155 THR C CB  1 
ATOM   8407  O OG1 . THR C 1 147 ? -37.547 50.979  51.840 1.00 103.71 ? 155 THR C OG1 1 
ATOM   8408  C CG2 . THR C 1 147 ? -39.471 51.010  53.114 1.00 109.88 ? 155 THR C CG2 1 
ATOM   8409  N N   . ASP C 1 148 ? -35.397 53.145  53.488 1.00 111.61 ? 156 ASP C N   1 
ATOM   8410  C CA  . ASP C 1 148 ? -34.050 53.567  53.109 1.00 91.02  ? 156 ASP C CA  1 
ATOM   8411  C C   . ASP C 1 148 ? -33.699 53.023  51.707 1.00 99.81  ? 156 ASP C C   1 
ATOM   8412  O O   . ASP C 1 148 ? -32.807 53.537  51.041 1.00 107.02 ? 156 ASP C O   1 
ATOM   8413  C CB  . ASP C 1 148 ? -33.046 53.214  54.202 1.00 96.81  ? 156 ASP C CB  1 
ATOM   8414  C CG  . ASP C 1 148 ? -32.732 51.714  54.275 1.00 135.36 ? 156 ASP C CG  1 
ATOM   8415  O OD1 . ASP C 1 148 ? -33.686 50.906  54.136 1.00 120.42 ? 156 ASP C OD1 1 
ATOM   8416  O OD2 . ASP C 1 148 ? -31.543 51.347  54.483 1.00 135.35 ? 156 ASP C OD2 1 
ATOM   8417  N N   . LYS C 1 149 ? -34.398 51.973  51.255 1.00 79.72  ? 157 LYS C N   1 
ATOM   8418  C CA  . LYS C 1 149 ? -34.099 51.176  50.071 1.00 68.90  ? 157 LYS C CA  1 
ATOM   8419  C C   . LYS C 1 149 ? -34.995 51.506  48.879 1.00 64.83  ? 157 LYS C C   1 
ATOM   8420  O O   . LYS C 1 149 ? -34.582 51.351  47.728 1.00 46.92  ? 157 LYS C O   1 
ATOM   8421  C CB  . LYS C 1 149 ? -34.521 49.749  50.455 1.00 64.59  ? 157 LYS C CB  1 
ATOM   8422  C CG  . LYS C 1 149 ? -33.885 49.030  51.668 1.00 93.41  ? 157 LYS C CG  1 
ATOM   8423  C CD  . LYS C 1 149 ? -32.380 48.813  51.484 1.00 95.88  ? 157 LYS C CD  1 
ATOM   8424  C CE  . LYS C 1 149 ? -31.635 47.895  52.394 1.00 94.50  ? 157 LYS C CE  1 
ATOM   8425  N NZ  . LYS C 1 149 ? -30.223 47.821  51.962 1.00 111.37 ? 157 LYS C NZ  1 
ATOM   8426  N N   . LYS C 1 150 ? -36.273 51.809  49.125 1.00 69.00  ? 158 LYS C N   1 
ATOM   8427  C CA  . LYS C 1 150 ? -37.113 52.169  47.987 1.00 62.90  ? 158 LYS C CA  1 
ATOM   8428  C C   . LYS C 1 150 ? -38.329 53.001  48.371 1.00 59.27  ? 158 LYS C C   1 
ATOM   8429  O O   . LYS C 1 150 ? -38.929 52.878  49.440 1.00 58.36  ? 158 LYS C O   1 
ATOM   8430  C CB  . LYS C 1 150 ? -37.413 51.284  46.764 1.00 63.68  ? 158 LYS C CB  1 
ATOM   8431  C CG  . LYS C 1 150 ? -37.503 52.259  45.537 1.00 80.90  ? 158 LYS C CG  1 
ATOM   8432  C CD  . LYS C 1 150 ? -37.119 51.959  44.072 1.00 109.56 ? 158 LYS C CD  1 
ATOM   8433  C CE  . LYS C 1 150 ? -35.690 51.551  43.707 1.00 110.83 ? 158 LYS C CE  1 
ATOM   8434  N NZ  . LYS C 1 150 ? -35.571 50.574  42.607 1.00 105.12 ? 158 LYS C NZ  1 
ATOM   8435  N N   . LYS C 1 151 ? -38.670 53.887  47.429 1.00 59.72  ? 159 LYS C N   1 
ATOM   8436  C CA  . LYS C 1 151 ? -39.909 54.642  47.460 1.00 89.01  ? 159 LYS C CA  1 
ATOM   8437  C C   . LYS C 1 151 ? -41.008 53.675  47.039 1.00 89.63  ? 159 LYS C C   1 
ATOM   8438  O O   . LYS C 1 151 ? -40.952 53.167  45.936 1.00 109.92 ? 159 LYS C O   1 
ATOM   8439  C CB  . LYS C 1 151 ? -39.760 55.790  46.453 1.00 76.35  ? 159 LYS C CB  1 
ATOM   8440  C CG  . LYS C 1 151 ? -38.713 56.821  46.908 1.00 95.68  ? 159 LYS C CG  1 
ATOM   8441  C CD  . LYS C 1 151 ? -38.939 58.195  46.278 1.00 130.35 ? 159 LYS C CD  1 
ATOM   8442  C CE  . LYS C 1 151 ? -37.786 59.078  45.934 1.00 105.57 ? 159 LYS C CE  1 
ATOM   8443  N NZ  . LYS C 1 151 ? -38.213 60.470  46.111 1.00 76.09  ? 159 LYS C NZ  1 
ATOM   8444  N N   . ILE C 1 152 ? -41.935 53.345  47.952 1.00 66.33  ? 160 ILE C N   1 
ATOM   8445  C CA  . ILE C 1 152 ? -42.811 52.200  47.738 1.00 68.59  ? 160 ILE C CA  1 
ATOM   8446  C C   . ILE C 1 152 ? -44.154 52.729  47.251 1.00 100.97 ? 160 ILE C C   1 
ATOM   8447  O O   . ILE C 1 152 ? -44.694 52.246  46.255 1.00 111.24 ? 160 ILE C O   1 
ATOM   8448  C CB  . ILE C 1 152 ? -43.031 51.384  49.027 1.00 85.13  ? 160 ILE C CB  1 
ATOM   8449  C CG1 . ILE C 1 152 ? -41.715 50.921  49.689 1.00 73.94  ? 160 ILE C CG1 1 
ATOM   8450  C CG2 . ILE C 1 152 ? -43.993 50.216  48.771 1.00 57.02  ? 160 ILE C CG2 1 
ATOM   8451  C CD1 . ILE C 1 152 ? -40.804 50.109  48.788 1.00 73.71  ? 160 ILE C CD1 1 
ATOM   8452  N N   . SER C 1 153 ? -44.762 53.652  48.015 1.00 112.94 ? 161 SER C N   1 
ATOM   8453  C CA  . SER C 1 153 ? -46.033 54.230  47.606 1.00 102.49 ? 161 SER C CA  1 
ATOM   8454  C C   . SER C 1 153 ? -45.790 55.182  46.450 1.00 96.68  ? 161 SER C C   1 
ATOM   8455  O O   . SER C 1 153 ? -44.802 55.911  46.472 1.00 110.37 ? 161 SER C O   1 
ATOM   8456  C CB  . SER C 1 153 ? -46.657 54.991  48.712 1.00 117.52 ? 161 SER C CB  1 
ATOM   8457  O OG  . SER C 1 153 ? -47.786 55.693  48.209 1.00 87.93  ? 161 SER C OG  1 
ATOM   8458  N N   . ALA C 1 154 ? -46.704 55.188  45.472 1.00 78.95  ? 162 ALA C N   1 
ATOM   8459  C CA  . ALA C 1 154 ? -46.632 56.124  44.363 1.00 62.41  ? 162 ALA C CA  1 
ATOM   8460  C C   . ALA C 1 154 ? -46.574 57.564  44.849 1.00 64.09  ? 162 ALA C C   1 
ATOM   8461  O O   . ALA C 1 154 ? -45.865 58.385  44.265 1.00 85.44  ? 162 ALA C O   1 
ATOM   8462  C CB  . ALA C 1 154 ? -47.805 55.910  43.461 1.00 75.17  ? 162 ALA C CB  1 
ATOM   8463  N N   . THR C 1 155 ? -47.269 57.849  45.955 1.00 68.24  ? 163 THR C N   1 
ATOM   8464  C CA  . THR C 1 155 ? -47.193 59.150  46.613 1.00 74.94  ? 163 THR C CA  1 
ATOM   8465  C C   . THR C 1 155 ? -45.727 59.471  46.891 1.00 77.40  ? 163 THR C C   1 
ATOM   8466  O O   . THR C 1 155 ? -45.242 60.553  46.554 1.00 78.51  ? 163 THR C O   1 
ATOM   8467  C CB  . THR C 1 155 ? -47.997 59.170  47.909 1.00 76.52  ? 163 THR C CB  1 
ATOM   8468  O OG1 . THR C 1 155 ? -49.302 58.645  47.668 1.00 104.98 ? 163 THR C OG1 1 
ATOM   8469  C CG2 . THR C 1 155 ? -48.094 60.576  48.461 1.00 72.31  ? 163 THR C CG2 1 
ATOM   8470  N N   . SER C 1 156 ? -44.999 58.473  47.395 1.00 76.80  ? 164 SER C N   1 
ATOM   8471  C CA  . SER C 1 156 ? -43.618 58.700  47.785 1.00 94.21  ? 164 SER C CA  1 
ATOM   8472  C C   . SER C 1 156 ? -42.643 58.659  46.603 1.00 111.47 ? 164 SER C C   1 
ATOM   8473  O O   . SER C 1 156 ? -41.503 59.130  46.735 1.00 125.28 ? 164 SER C O   1 
ATOM   8474  C CB  . SER C 1 156 ? -43.232 57.680  48.794 1.00 98.22  ? 164 SER C CB  1 
ATOM   8475  O OG  . SER C 1 156 ? -43.586 58.102  50.093 1.00 108.65 ? 164 SER C OG  1 
ATOM   8476  N N   . ILE C 1 157 ? -43.093 58.087  45.472 1.00 95.64  ? 165 ILE C N   1 
ATOM   8477  C CA  . ILE C 1 157 ? -42.299 58.035  44.256 1.00 81.79  ? 165 ILE C CA  1 
ATOM   8478  C C   . ILE C 1 157 ? -42.335 59.377  43.544 1.00 86.93  ? 165 ILE C C   1 
ATOM   8479  O O   . ILE C 1 157 ? -41.272 59.862  43.145 1.00 92.66  ? 165 ILE C O   1 
ATOM   8480  C CB  . ILE C 1 157 ? -42.856 56.965  43.306 1.00 81.18  ? 165 ILE C CB  1 
ATOM   8481  C CG1 . ILE C 1 157 ? -42.810 55.592  43.958 1.00 55.81  ? 165 ILE C CG1 1 
ATOM   8482  C CG2 . ILE C 1 157 ? -42.161 57.023  41.929 1.00 65.39  ? 165 ILE C CG2 1 
ATOM   8483  C CD1 . ILE C 1 157 ? -43.551 54.575  43.123 1.00 38.44  ? 165 ILE C CD1 1 
ATOM   8484  N N   . PHE C 1 158 ? -43.558 59.923  43.355 1.00 64.94  ? 166 PHE C N   1 
ATOM   8485  C CA  . PHE C 1 158 ? -43.704 61.075  42.483 1.00 75.54  ? 166 PHE C CA  1 
ATOM   8486  C C   . PHE C 1 158 ? -43.719 62.393  43.250 1.00 76.60  ? 166 PHE C C   1 
ATOM   8487  O O   . PHE C 1 158 ? -43.558 63.442  42.616 1.00 70.12  ? 166 PHE C O   1 
ATOM   8488  C CB  . PHE C 1 158 ? -44.993 60.970  41.688 1.00 64.10  ? 166 PHE C CB  1 
ATOM   8489  C CG  . PHE C 1 158 ? -45.013 59.794  40.743 1.00 57.00  ? 166 PHE C CG  1 
ATOM   8490  C CD1 . PHE C 1 158 ? -44.295 59.844  39.545 1.00 45.89  ? 166 PHE C CD1 1 
ATOM   8491  C CD2 . PHE C 1 158 ? -45.811 58.682  41.034 1.00 74.39  ? 166 PHE C CD2 1 
ATOM   8492  C CE1 . PHE C 1 158 ? -44.313 58.758  38.658 1.00 44.70  ? 166 PHE C CE1 1 
ATOM   8493  C CE2 . PHE C 1 158 ? -45.830 57.599  40.142 1.00 83.01  ? 166 PHE C CE2 1 
ATOM   8494  C CZ  . PHE C 1 158 ? -45.092 57.644  38.942 1.00 59.74  ? 166 PHE C CZ  1 
ATOM   8495  N N   . PHE C 1 159 ? -43.892 62.307  44.590 1.00 51.55  ? 167 PHE C N   1 
ATOM   8496  C CA  . PHE C 1 159 ? -43.739 63.445  45.503 1.00 50.10  ? 167 PHE C CA  1 
ATOM   8497  C C   . PHE C 1 159 ? -42.663 63.120  46.545 1.00 54.45  ? 167 PHE C C   1 
ATOM   8498  O O   . PHE C 1 159 ? -42.306 61.958  46.751 1.00 98.92  ? 167 PHE C O   1 
ATOM   8499  C CB  . PHE C 1 159 ? -45.108 63.734  46.125 1.00 47.30  ? 167 PHE C CB  1 
ATOM   8500  C CG  . PHE C 1 159 ? -46.226 63.817  45.081 1.00 67.22  ? 167 PHE C CG  1 
ATOM   8501  C CD1 . PHE C 1 159 ? -46.476 64.990  44.380 1.00 68.59  ? 167 PHE C CD1 1 
ATOM   8502  C CD2 . PHE C 1 159 ? -47.046 62.725  44.785 1.00 81.03  ? 167 PHE C CD2 1 
ATOM   8503  C CE1 . PHE C 1 159 ? -47.499 65.063  43.435 1.00 70.49  ? 167 PHE C CE1 1 
ATOM   8504  C CE2 . PHE C 1 159 ? -48.032 62.799  43.793 1.00 74.58  ? 167 PHE C CE2 1 
ATOM   8505  C CZ  . PHE C 1 159 ? -48.284 63.971  43.132 1.00 59.88  ? 167 PHE C CZ  1 
ATOM   8506  N N   . GLU C 1 160 ? -42.157 64.133  47.239 1.00 42.21  ? 168 GLU C N   1 
ATOM   8507  C CA  . GLU C 1 160 ? -41.268 63.881  48.376 1.00 56.52  ? 168 GLU C CA  1 
ATOM   8508  C C   . GLU C 1 160 ? -42.048 63.766  49.704 1.00 69.79  ? 168 GLU C C   1 
ATOM   8509  O O   . GLU C 1 160 ? -42.610 64.776  50.225 1.00 61.18  ? 168 GLU C O   1 
ATOM   8510  C CB  . GLU C 1 160 ? -40.201 64.976  48.400 1.00 53.93  ? 168 GLU C CB  1 
ATOM   8511  C CG  . GLU C 1 160 ? -39.304 64.989  47.162 1.00 78.09  ? 168 GLU C CG  1 
ATOM   8512  C CD  . GLU C 1 160 ? -38.474 63.775  46.744 1.00 103.60 ? 168 GLU C CD  1 
ATOM   8513  O OE1 . GLU C 1 160 ? -37.478 63.308  47.410 1.00 67.12  ? 168 GLU C OE1 1 
ATOM   8514  O OE2 . GLU C 1 160 ? -38.859 63.315  45.624 1.00 122.92 ? 168 GLU C OE2 1 
ATOM   8515  N N   . SER C 1 161 ? -42.086 62.528  50.261 1.00 42.76  ? 169 SER C N   1 
ATOM   8516  C CA  . SER C 1 161 ? -42.941 62.393  51.436 1.00 47.56  ? 169 SER C CA  1 
ATOM   8517  C C   . SER C 1 161 ? -42.066 62.244  52.663 1.00 47.95  ? 169 SER C C   1 
ATOM   8518  O O   . SER C 1 161 ? -40.923 61.890  52.452 1.00 58.11  ? 169 SER C O   1 
ATOM   8519  C CB  . SER C 1 161 ? -43.840 61.177  51.312 1.00 57.65  ? 169 SER C CB  1 
ATOM   8520  O OG  . SER C 1 161 ? -43.350 60.019  51.989 1.00 41.95  ? 169 SER C OG  1 
ATOM   8521  N N   . MET C 1 162 ? -42.601 62.530  53.849 1.00 45.04  ? 170 MET C N   1 
ATOM   8522  C CA  . MET C 1 162 ? -41.980 62.263  55.138 1.00 50.79  ? 170 MET C CA  1 
ATOM   8523  C C   . MET C 1 162 ? -43.118 62.000  56.114 1.00 55.40  ? 170 MET C C   1 
ATOM   8524  O O   . MET C 1 162 ? -44.077 62.782  56.150 1.00 70.68  ? 170 MET C O   1 
ATOM   8525  C CB  . MET C 1 162 ? -41.245 63.502  55.714 1.00 48.87  ? 170 MET C CB  1 
ATOM   8526  C CG  . MET C 1 162 ? -40.565 63.141  57.013 1.00 52.69  ? 170 MET C CG  1 
ATOM   8527  S SD  . MET C 1 162 ? -39.269 64.164  57.697 1.00 73.26  ? 170 MET C SD  1 
ATOM   8528  C CE  . MET C 1 162 ? -40.334 65.530  58.163 1.00 122.92 ? 170 MET C CE  1 
ATOM   8529  N N   . PRO C 1 163 ? -43.033 60.964  56.977 1.00 61.01  ? 171 PRO C N   1 
ATOM   8530  C CA  . PRO C 1 163 ? -44.068 60.723  58.013 1.00 60.74  ? 171 PRO C CA  1 
ATOM   8531  C C   . PRO C 1 163 ? -44.032 61.532  59.311 1.00 77.79  ? 171 PRO C C   1 
ATOM   8532  O O   . PRO C 1 163 ? -42.968 62.011  59.734 1.00 112.64 ? 171 PRO C O   1 
ATOM   8533  C CB  . PRO C 1 163 ? -43.908 59.238  58.319 1.00 49.02  ? 171 PRO C CB  1 
ATOM   8534  C CG  . PRO C 1 163 ? -42.397 59.028  58.081 1.00 64.81  ? 171 PRO C CG  1 
ATOM   8535  C CD  . PRO C 1 163 ? -41.971 59.945  56.931 1.00 57.96  ? 171 PRO C CD  1 
ATOM   8536  N N   . TYR C 1 164 ? -45.213 61.689  59.944 1.00 82.51  ? 172 TYR C N   1 
ATOM   8537  C CA  . TYR C 1 164 ? -45.315 62.212  61.310 1.00 90.53  ? 172 TYR C CA  1 
ATOM   8538  C C   . TYR C 1 164 ? -45.752 61.011  62.142 1.00 83.02  ? 172 TYR C C   1 
ATOM   8539  O O   . TYR C 1 164 ? -46.418 60.123  61.619 1.00 52.35  ? 172 TYR C O   1 
ATOM   8540  C CB  . TYR C 1 164 ? -46.207 63.459  61.527 1.00 87.14  ? 172 TYR C CB  1 
ATOM   8541  C CG  . TYR C 1 164 ? -47.674 63.402  61.079 1.00 77.03  ? 172 TYR C CG  1 
ATOM   8542  C CD1 . TYR C 1 164 ? -48.632 62.803  61.876 1.00 72.83  ? 172 TYR C CD1 1 
ATOM   8543  C CD2 . TYR C 1 164 ? -48.141 63.938  59.883 1.00 94.95  ? 172 TYR C CD2 1 
ATOM   8544  C CE1 . TYR C 1 164 ? -49.977 62.746  61.554 1.00 65.95  ? 172 TYR C CE1 1 
ATOM   8545  C CE2 . TYR C 1 164 ? -49.487 63.868  59.525 1.00 85.39  ? 172 TYR C CE2 1 
ATOM   8546  C CZ  . TYR C 1 164 ? -50.424 63.281  60.368 1.00 83.91  ? 172 TYR C CZ  1 
ATOM   8547  O OH  . TYR C 1 164 ? -51.781 63.085  60.157 1.00 78.54  ? 172 TYR C OH  1 
ATOM   8548  N N   . LYS C 1 165 ? -45.351 60.952  63.419 1.00 92.67  ? 173 LYS C N   1 
ATOM   8549  C CA  . LYS C 1 165 ? -45.458 59.664  64.094 1.00 89.33  ? 173 LYS C CA  1 
ATOM   8550  C C   . LYS C 1 165 ? -46.388 59.778  65.292 1.00 94.18  ? 173 LYS C C   1 
ATOM   8551  O O   . LYS C 1 165 ? -46.791 60.893  65.651 1.00 80.38  ? 173 LYS C O   1 
ATOM   8552  C CB  . LYS C 1 165 ? -44.108 58.997  64.390 1.00 78.34  ? 173 LYS C CB  1 
ATOM   8553  C CG  . LYS C 1 165 ? -43.325 58.715  63.121 1.00 87.43  ? 173 LYS C CG  1 
ATOM   8554  C CD  . LYS C 1 165 ? -42.153 57.778  63.382 1.00 101.63 ? 173 LYS C CD  1 
ATOM   8555  C CE  . LYS C 1 165 ? -42.523 56.419  63.931 1.00 123.43 ? 173 LYS C CE  1 
ATOM   8556  N NZ  . LYS C 1 165 ? -42.756 55.377  62.925 1.00 134.95 ? 173 LYS C NZ  1 
ATOM   8557  N N   . VAL C 1 166 ? -46.650 58.610  65.909 1.00 72.97  ? 174 VAL C N   1 
ATOM   8558  C CA  . VAL C 1 166 ? -47.321 58.454  67.189 1.00 66.70  ? 174 VAL C CA  1 
ATOM   8559  C C   . VAL C 1 166 ? -46.243 58.516  68.278 1.00 69.51  ? 174 VAL C C   1 
ATOM   8560  O O   . VAL C 1 166 ? -45.181 57.915  68.138 1.00 85.53  ? 174 VAL C O   1 
ATOM   8561  C CB  . VAL C 1 166 ? -47.887 57.006  67.136 1.00 58.66  ? 174 VAL C CB  1 
ATOM   8562  C CG1 . VAL C 1 166 ? -48.456 56.479  68.453 1.00 37.28  ? 174 VAL C CG1 1 
ATOM   8563  C CG2 . VAL C 1 166 ? -48.892 56.796  66.017 1.00 50.53  ? 174 VAL C CG2 1 
ATOM   8564  N N   . ASN C 1 167 ? -46.488 59.200  69.387 1.00 58.53  ? 175 ASN C N   1 
ATOM   8565  C CA  . ASN C 1 167 ? -45.748 58.961  70.623 1.00 72.42  ? 175 ASN C CA  1 
ATOM   8566  C C   . ASN C 1 167 ? -45.968 57.505  71.021 1.00 82.70  ? 175 ASN C C   1 
ATOM   8567  O O   . ASN C 1 167 ? -47.095 57.163  71.438 1.00 63.59  ? 175 ASN C O   1 
ATOM   8568  C CB  . ASN C 1 167 ? -46.492 59.589  71.798 1.00 96.93  ? 175 ASN C CB  1 
ATOM   8569  C CG  . ASN C 1 167 ? -45.729 59.483  73.090 1.00 105.33 ? 175 ASN C CG  1 
ATOM   8570  O OD1 . ASN C 1 167 ? -45.353 58.388  73.509 1.00 90.51  ? 175 ASN C OD1 1 
ATOM   8571  N ND2 . ASN C 1 167 ? -45.505 60.611  73.742 1.00 190.09 ? 175 ASN C ND2 1 
ATOM   8572  N N   . PRO C 1 168 ? -44.914 56.651  71.008 1.00 83.85  ? 176 PRO C N   1 
ATOM   8573  C CA  . PRO C 1 168 ? -45.132 55.207  71.123 1.00 75.91  ? 176 PRO C CA  1 
ATOM   8574  C C   . PRO C 1 168 ? -45.693 54.819  72.493 1.00 76.70  ? 176 PRO C C   1 
ATOM   8575  O O   . PRO C 1 168 ? -46.311 53.764  72.558 1.00 66.60  ? 176 PRO C O   1 
ATOM   8576  C CB  . PRO C 1 168 ? -43.772 54.562  70.780 1.00 65.11  ? 176 PRO C CB  1 
ATOM   8577  C CG  . PRO C 1 168 ? -42.788 55.686  71.079 1.00 82.37  ? 176 PRO C CG  1 
ATOM   8578  C CD  . PRO C 1 168 ? -43.500 57.051  70.938 1.00 77.52  ? 176 PRO C CD  1 
ATOM   8579  N N   . ASP C 1 169 ? -45.541 55.690  73.524 1.00 82.15  ? 177 ASP C N   1 
ATOM   8580  C CA  . ASP C 1 169 ? -46.135 55.428  74.832 1.00 73.34  ? 177 ASP C CA  1 
ATOM   8581  C C   . ASP C 1 169 ? -47.629 55.762  74.800 1.00 72.88  ? 177 ASP C C   1 
ATOM   8582  O O   . ASP C 1 169 ? -48.414 54.884  74.389 1.00 69.08  ? 177 ASP C O   1 
ATOM   8583  C CB  . ASP C 1 169 ? -45.457 56.162  75.965 1.00 70.09  ? 177 ASP C CB  1 
ATOM   8584  C CG  . ASP C 1 169 ? -43.946 56.264  75.838 1.00 96.74  ? 177 ASP C CG  1 
ATOM   8585  O OD1 . ASP C 1 169 ? -43.355 55.463  75.036 1.00 96.77  ? 177 ASP C OD1 1 
ATOM   8586  O OD2 . ASP C 1 169 ? -43.387 57.177  76.520 1.00 58.04  ? 177 ASP C OD2 1 
ATOM   8587  N N   . THR C 1 170 ? -48.000 57.029  75.099 1.00 57.72  ? 178 THR C N   1 
ATOM   8588  C CA  . THR C 1 170 ? -49.384 57.451  74.853 1.00 77.53  ? 178 THR C CA  1 
ATOM   8589  C C   . THR C 1 170 ? -50.122 56.593  73.801 1.00 93.03  ? 178 THR C C   1 
ATOM   8590  O O   . THR C 1 170 ? -51.272 56.246  74.058 1.00 107.98 ? 178 THR C O   1 
ATOM   8591  C CB  . THR C 1 170 ? -49.565 58.951  74.582 1.00 84.09  ? 178 THR C CB  1 
ATOM   8592  O OG1 . THR C 1 170 ? -49.355 59.397  73.249 1.00 103.93 ? 178 THR C OG1 1 
ATOM   8593  C CG2 . THR C 1 170 ? -48.680 59.844  75.415 1.00 83.95  ? 178 THR C CG2 1 
ATOM   8594  N N   . GLY C 1 171 ? -49.516 56.258  72.635 1.00 71.87  ? 179 GLY C N   1 
ATOM   8595  C CA  . GLY C 1 171 ? -50.287 55.568  71.604 1.00 85.46  ? 179 GLY C CA  1 
ATOM   8596  C C   . GLY C 1 171 ? -51.012 56.560  70.696 1.00 105.34 ? 179 GLY C C   1 
ATOM   8597  O O   . GLY C 1 171 ? -51.679 56.154  69.733 1.00 101.83 ? 179 GLY C O   1 
ATOM   8598  N N   . TYR C 1 172 ? -50.863 57.858  71.008 1.00 106.16 ? 180 TYR C N   1 
ATOM   8599  C CA  . TYR C 1 172 ? -51.476 58.960  70.278 1.00 91.12  ? 180 TYR C CA  1 
ATOM   8600  C C   . TYR C 1 172 ? -50.468 59.594  69.322 1.00 89.42  ? 180 TYR C C   1 
ATOM   8601  O O   . TYR C 1 172 ? -49.247 59.497  69.461 1.00 108.80 ? 180 TYR C O   1 
ATOM   8602  C CB  . TYR C 1 172 ? -51.937 60.039  71.254 1.00 74.65  ? 180 TYR C CB  1 
ATOM   8603  C CG  . TYR C 1 172 ? -53.220 59.677  72.000 1.00 89.74  ? 180 TYR C CG  1 
ATOM   8604  C CD1 . TYR C 1 172 ? -53.252 58.779  73.063 1.00 115.76 ? 180 TYR C CD1 1 
ATOM   8605  C CD2 . TYR C 1 172 ? -54.410 60.290  71.671 1.00 81.70  ? 180 TYR C CD2 1 
ATOM   8606  C CE1 . TYR C 1 172 ? -54.420 58.461  73.738 1.00 123.95 ? 180 TYR C CE1 1 
ATOM   8607  C CE2 . TYR C 1 172 ? -55.587 60.004  72.342 1.00 88.90  ? 180 TYR C CE2 1 
ATOM   8608  C CZ  . TYR C 1 172 ? -55.599 59.099  73.388 1.00 109.27 ? 180 TYR C CZ  1 
ATOM   8609  O OH  . TYR C 1 172 ? -56.780 58.806  74.023 1.00 73.78  ? 180 TYR C OH  1 
ATOM   8610  N N   . ILE C 1 173 ? -51.007 60.291  68.343 1.00 80.42  ? 181 ILE C N   1 
ATOM   8611  C CA  . ILE C 1 173 ? -50.191 61.010  67.384 1.00 68.37  ? 181 ILE C CA  1 
ATOM   8612  C C   . ILE C 1 173 ? -49.457 62.097  68.155 1.00 69.18  ? 181 ILE C C   1 
ATOM   8613  O O   . ILE C 1 173 ? -50.061 62.803  68.961 1.00 89.75  ? 181 ILE C O   1 
ATOM   8614  C CB  . ILE C 1 173 ? -51.113 61.628  66.312 1.00 61.66  ? 181 ILE C CB  1 
ATOM   8615  C CG1 . ILE C 1 173 ? -51.689 60.574  65.388 1.00 68.04  ? 181 ILE C CG1 1 
ATOM   8616  C CG2 . ILE C 1 173 ? -50.381 62.662  65.501 1.00 58.89  ? 181 ILE C CG2 1 
ATOM   8617  C CD1 . ILE C 1 173 ? -52.805 61.092  64.515 1.00 82.05  ? 181 ILE C CD1 1 
ATOM   8618  N N   . ASN C 1 174 ? -48.168 62.234  67.863 1.00 63.24  ? 182 ASN C N   1 
ATOM   8619  C CA  . ASN C 1 174 ? -47.313 63.224  68.470 1.00 61.87  ? 182 ASN C CA  1 
ATOM   8620  C C   . ASN C 1 174 ? -47.316 64.483  67.616 1.00 71.23  ? 182 ASN C C   1 
ATOM   8621  O O   . ASN C 1 174 ? -46.376 64.729  66.823 1.00 70.97  ? 182 ASN C O   1 
ATOM   8622  C CB  . ASN C 1 174 ? -45.917 62.668  68.655 1.00 83.09  ? 182 ASN C CB  1 
ATOM   8623  C CG  . ASN C 1 174 ? -45.147 63.577  69.557 1.00 83.07  ? 182 ASN C CG  1 
ATOM   8624  O OD1 . ASN C 1 174 ? -44.953 64.746  69.238 1.00 81.99  ? 182 ASN C OD1 1 
ATOM   8625  N ND2 . ASN C 1 174 ? -44.769 63.093  70.721 1.00 141.29 ? 182 ASN C ND2 1 
ATOM   8626  N N   . TYR C 1 175 ? -48.392 65.265  67.813 1.00 76.23  ? 183 TYR C N   1 
ATOM   8627  C CA  . TYR C 1 175 ? -48.570 66.507  67.078 1.00 84.54  ? 183 TYR C CA  1 
ATOM   8628  C C   . TYR C 1 175 ? -47.415 67.462  67.372 1.00 85.04  ? 183 TYR C C   1 
ATOM   8629  O O   . TYR C 1 175 ? -47.139 68.335  66.561 1.00 91.60  ? 183 TYR C O   1 
ATOM   8630  C CB  . TYR C 1 175 ? -49.932 67.164  67.290 1.00 69.29  ? 183 TYR C CB  1 
ATOM   8631  C CG  . TYR C 1 175 ? -51.125 66.255  66.990 1.00 60.45  ? 183 TYR C CG  1 
ATOM   8632  C CD1 . TYR C 1 175 ? -51.714 66.229  65.753 1.00 60.37  ? 183 TYR C CD1 1 
ATOM   8633  C CD2 . TYR C 1 175 ? -51.716 65.482  67.974 1.00 71.23  ? 183 TYR C CD2 1 
ATOM   8634  C CE1 . TYR C 1 175 ? -52.823 65.435  65.493 1.00 83.25  ? 183 TYR C CE1 1 
ATOM   8635  C CE2 . TYR C 1 175 ? -52.850 64.722  67.759 1.00 83.42  ? 183 TYR C CE2 1 
ATOM   8636  C CZ  . TYR C 1 175 ? -53.401 64.676  66.496 1.00 94.22  ? 183 TYR C CZ  1 
ATOM   8637  O OH  . TYR C 1 175 ? -54.494 63.872  66.278 1.00 102.44 ? 183 TYR C OH  1 
ATOM   8638  N N   . ASP C 1 176 ? -46.705 67.270  68.486 1.00 65.85  ? 184 ASP C N   1 
ATOM   8639  C CA  . ASP C 1 176 ? -45.599 68.168  68.780 1.00 72.07  ? 184 ASP C CA  1 
ATOM   8640  C C   . ASP C 1 176 ? -44.426 67.943  67.837 1.00 94.92  ? 184 ASP C C   1 
ATOM   8641  O O   . ASP C 1 176 ? -43.812 68.903  67.330 1.00 87.59  ? 184 ASP C O   1 
ATOM   8642  C CB  . ASP C 1 176 ? -45.146 68.099  70.225 1.00 65.71  ? 184 ASP C CB  1 
ATOM   8643  C CG  . ASP C 1 176 ? -46.254 68.283  71.229 1.00 72.18  ? 184 ASP C CG  1 
ATOM   8644  O OD1 . ASP C 1 176 ? -47.333 68.782  70.859 1.00 96.75  ? 184 ASP C OD1 1 
ATOM   8645  O OD2 . ASP C 1 176 ? -46.051 67.809  72.321 1.00 82.05  ? 184 ASP C OD2 1 
ATOM   8646  N N   . GLN C 1 177 ? -44.083 66.670  67.627 1.00 112.74 ? 185 GLN C N   1 
ATOM   8647  C CA  . GLN C 1 177 ? -42.975 66.359  66.736 1.00 100.82 ? 185 GLN C CA  1 
ATOM   8648  C C   . GLN C 1 177 ? -43.343 66.872  65.341 1.00 82.72  ? 185 GLN C C   1 
ATOM   8649  O O   . GLN C 1 177 ? -42.468 67.344  64.597 1.00 61.10  ? 185 GLN C O   1 
ATOM   8650  C CB  . GLN C 1 177 ? -42.570 64.879  66.866 1.00 88.70  ? 185 GLN C CB  1 
ATOM   8651  C CG  . GLN C 1 177 ? -41.804 64.277  65.691 1.00 88.13  ? 185 GLN C CG  1 
ATOM   8652  C CD  . GLN C 1 177 ? -42.564 63.101  65.121 1.00 142.70 ? 185 GLN C CD  1 
ATOM   8653  O OE1 . GLN C 1 177 ? -43.783 63.150  64.858 1.00 119.37 ? 185 GLN C OE1 1 
ATOM   8654  N NE2 . GLN C 1 177 ? -41.822 62.014  64.989 1.00 176.43 ? 185 GLN C NE2 1 
ATOM   8655  N N   . LEU C 1 178 ? -44.640 66.744  64.990 1.00 70.72  ? 186 LEU C N   1 
ATOM   8656  C CA  . LEU C 1 178 ? -45.169 67.190  63.716 1.00 59.98  ? 186 LEU C CA  1 
ATOM   8657  C C   . LEU C 1 178 ? -44.817 68.650  63.557 1.00 52.33  ? 186 LEU C C   1 
ATOM   8658  O O   . LEU C 1 178 ? -44.247 69.022  62.536 1.00 38.53  ? 186 LEU C O   1 
ATOM   8659  C CB  . LEU C 1 178 ? -46.663 66.934  63.526 1.00 47.17  ? 186 LEU C CB  1 
ATOM   8660  C CG  . LEU C 1 178 ? -47.267 67.446  62.210 1.00 43.86  ? 186 LEU C CG  1 
ATOM   8661  C CD1 . LEU C 1 178 ? -46.442 67.220  60.938 1.00 32.32  ? 186 LEU C CD1 1 
ATOM   8662  C CD2 . LEU C 1 178 ? -48.729 66.918  61.994 1.00 45.88  ? 186 LEU C CD2 1 
ATOM   8663  N N   . GLU C 1 179 ? -45.165 69.431  64.574 1.00 60.15  ? 187 GLU C N   1 
ATOM   8664  C CA  . GLU C 1 179 ? -44.965 70.871  64.579 1.00 75.76  ? 187 GLU C CA  1 
ATOM   8665  C C   . GLU C 1 179 ? -43.535 71.228  64.176 1.00 73.88  ? 187 GLU C C   1 
ATOM   8666  O O   . GLU C 1 179 ? -43.387 71.999  63.168 1.00 69.40  ? 187 GLU C O   1 
ATOM   8667  C CB  . GLU C 1 179 ? -45.359 71.460  65.931 1.00 56.29  ? 187 GLU C CB  1 
ATOM   8668  C CG  . GLU C 1 179 ? -45.640 72.949  65.837 1.00 70.44  ? 187 GLU C CG  1 
ATOM   8669  C CD  . GLU C 1 179 ? -46.070 73.526  67.162 1.00 91.23  ? 187 GLU C CD  1 
ATOM   8670  O OE1 . GLU C 1 179 ? -47.180 74.109  67.212 1.00 135.45 ? 187 GLU C OE1 1 
ATOM   8671  O OE2 . GLU C 1 179 ? -45.248 73.460  68.113 1.00 101.33 ? 187 GLU C OE2 1 
ATOM   8672  N N   . GLU C 1 180 ? -42.560 70.616  64.911 1.00 52.64  ? 188 GLU C N   1 
ATOM   8673  C CA  . GLU C 1 180 ? -41.153 71.031  64.685 1.00 71.92  ? 188 GLU C CA  1 
ATOM   8674  C C   . GLU C 1 180 ? -40.689 70.531  63.322 1.00 78.97  ? 188 GLU C C   1 
ATOM   8675  O O   . GLU C 1 180 ? -40.093 71.300  62.581 1.00 87.15  ? 188 GLU C O   1 
ATOM   8676  C CB  . GLU C 1 180 ? -39.841 70.782  65.464 1.00 58.49  ? 188 GLU C CB  1 
ATOM   8677  C CG  . GLU C 1 180 ? -39.474 71.709  66.626 1.00 67.00  ? 188 GLU C CG  1 
ATOM   8678  C CD  . GLU C 1 180 ? -39.966 71.064  67.932 1.00 110.33 ? 188 GLU C CD  1 
ATOM   8679  O OE1 . GLU C 1 180 ? -39.479 69.951  68.249 1.00 139.57 ? 188 GLU C OE1 1 
ATOM   8680  O OE2 . GLU C 1 180 ? -40.913 71.566  68.596 1.00 132.91 ? 188 GLU C OE2 1 
ATOM   8681  N N   . ASN C 1 181 ? -41.006 69.280  62.980 1.00 59.39  ? 189 ASN C N   1 
ATOM   8682  C CA  . ASN C 1 181 ? -40.523 68.722  61.738 1.00 56.20  ? 189 ASN C CA  1 
ATOM   8683  C C   . ASN C 1 181 ? -41.180 69.425  60.563 1.00 70.87  ? 189 ASN C C   1 
ATOM   8684  O O   . ASN C 1 181 ? -40.528 69.577  59.533 1.00 66.75  ? 189 ASN C O   1 
ATOM   8685  C CB  . ASN C 1 181 ? -40.833 67.236  61.672 1.00 72.71  ? 189 ASN C CB  1 
ATOM   8686  C CG  . ASN C 1 181 ? -39.776 66.428  62.387 1.00 82.64  ? 189 ASN C CG  1 
ATOM   8687  O OD1 . ASN C 1 181 ? -38.681 66.982  62.629 1.00 52.91  ? 189 ASN C OD1 1 
ATOM   8688  N ND2 . ASN C 1 181 ? -40.088 65.156  62.669 1.00 99.38  ? 189 ASN C ND2 1 
ATOM   8689  N N   . ALA C 1 182 ? -42.471 69.784  60.677 1.00 64.51  ? 190 ALA C N   1 
ATOM   8690  C CA  . ALA C 1 182 ? -43.142 70.484  59.588 1.00 72.88  ? 190 ALA C CA  1 
ATOM   8691  C C   . ALA C 1 182 ? -42.367 71.755  59.256 1.00 73.69  ? 190 ALA C C   1 
ATOM   8692  O O   . ALA C 1 182 ? -42.173 72.060  58.082 1.00 81.63  ? 190 ALA C O   1 
ATOM   8693  C CB  . ALA C 1 182 ? -44.576 70.786  59.901 1.00 68.05  ? 190 ALA C CB  1 
ATOM   8694  N N   . ARG C 1 183 ? -41.827 72.433  60.274 1.00 71.09  ? 191 ARG C N   1 
ATOM   8695  C CA  . ARG C 1 183 ? -41.098 73.678  60.037 1.00 64.64  ? 191 ARG C CA  1 
ATOM   8696  C C   . ARG C 1 183 ? -39.789 73.431  59.293 1.00 66.70  ? 191 ARG C C   1 
ATOM   8697  O O   . ARG C 1 183 ? -39.321 74.331  58.605 1.00 95.29  ? 191 ARG C O   1 
ATOM   8698  C CB  . ARG C 1 183 ? -40.758 74.467  61.302 1.00 63.65  ? 191 ARG C CB  1 
ATOM   8699  C CG  . ARG C 1 183 ? -42.002 74.722  62.140 1.00 71.40  ? 191 ARG C CG  1 
ATOM   8700  C CD  . ARG C 1 183 ? -41.884 75.811  63.215 1.00 68.42  ? 191 ARG C CD  1 
ATOM   8701  N NE  . ARG C 1 183 ? -41.711 75.222  64.548 1.00 80.12  ? 191 ARG C NE  1 
ATOM   8702  C CZ  . ARG C 1 183 ? -42.691 75.056  65.435 1.00 95.72  ? 191 ARG C CZ  1 
ATOM   8703  N NH1 . ARG C 1 183 ? -42.505 74.224  66.449 1.00 83.29  ? 191 ARG C NH1 1 
ATOM   8704  N NH2 . ARG C 1 183 ? -43.881 75.631  65.288 1.00 82.80  ? 191 ARG C NH2 1 
ATOM   8705  N N   . LEU C 1 184 ? -39.205 72.232  59.453 1.00 57.74  ? 192 LEU C N   1 
ATOM   8706  C CA  . LEU C 1 184 ? -37.953 71.877  58.798 1.00 74.22  ? 192 LEU C CA  1 
ATOM   8707  C C   . LEU C 1 184 ? -38.168 71.317  57.400 1.00 83.75  ? 192 LEU C C   1 
ATOM   8708  O O   . LEU C 1 184 ? -37.384 71.607  56.506 1.00 95.12  ? 192 LEU C O   1 
ATOM   8709  C CB  . LEU C 1 184 ? -37.244 70.840  59.653 1.00 71.82  ? 192 LEU C CB  1 
ATOM   8710  C CG  . LEU C 1 184 ? -36.820 71.326  61.034 1.00 62.50  ? 192 LEU C CG  1 
ATOM   8711  C CD1 . LEU C 1 184 ? -36.221 70.165  61.878 1.00 48.93  ? 192 LEU C CD1 1 
ATOM   8712  C CD2 . LEU C 1 184 ? -35.835 72.488  60.743 1.00 70.43  ? 192 LEU C CD2 1 
ATOM   8713  N N   . PHE C 1 185 ? -39.195 70.477  57.240 1.00 72.14  ? 193 PHE C N   1 
ATOM   8714  C CA  . PHE C 1 185 ? -39.491 69.825  55.978 1.00 70.76  ? 193 PHE C CA  1 
ATOM   8715  C C   . PHE C 1 185 ? -40.289 70.704  54.999 1.00 67.16  ? 193 PHE C C   1 
ATOM   8716  O O   . PHE C 1 185 ? -40.173 70.471  53.794 1.00 54.44  ? 193 PHE C O   1 
ATOM   8717  C CB  . PHE C 1 185 ? -40.262 68.566  56.371 1.00 70.80  ? 193 PHE C CB  1 
ATOM   8718  C CG  . PHE C 1 185 ? -40.578 67.640  55.200 1.00 71.04  ? 193 PHE C CG  1 
ATOM   8719  C CD1 . PHE C 1 185 ? -39.541 67.005  54.539 1.00 52.15  ? 193 PHE C CD1 1 
ATOM   8720  C CD2 . PHE C 1 185 ? -41.887 67.384  54.776 1.00 80.78  ? 193 PHE C CD2 1 
ATOM   8721  C CE1 . PHE C 1 185 ? -39.779 66.185  53.466 1.00 61.93  ? 193 PHE C CE1 1 
ATOM   8722  C CE2 . PHE C 1 185 ? -42.107 66.537  53.700 1.00 102.09 ? 193 PHE C CE2 1 
ATOM   8723  C CZ  . PHE C 1 185 ? -41.053 65.954  53.041 1.00 90.67  ? 193 PHE C CZ  1 
ATOM   8724  N N   . HIS C 1 186 ? -41.055 71.705  55.501 1.00 69.59  ? 194 HIS C N   1 
ATOM   8725  C CA  . HIS C 1 186 ? -41.959 72.582  54.738 1.00 62.83  ? 194 HIS C CA  1 
ATOM   8726  C C   . HIS C 1 186 ? -42.920 71.767  53.871 1.00 51.97  ? 194 HIS C C   1 
ATOM   8727  O O   . HIS C 1 186 ? -42.760 71.672  52.645 1.00 51.43  ? 194 HIS C O   1 
ATOM   8728  C CB  . HIS C 1 186 ? -41.164 73.563  53.857 1.00 70.78  ? 194 HIS C CB  1 
ATOM   8729  C CG  . HIS C 1 186 ? -39.979 74.154  54.499 1.00 63.14  ? 194 HIS C CG  1 
ATOM   8730  N ND1 . HIS C 1 186 ? -40.212 75.288  55.233 1.00 79.04  ? 194 HIS C ND1 1 
ATOM   8731  C CD2 . HIS C 1 186 ? -38.670 73.934  54.543 1.00 70.29  ? 194 HIS C CD2 1 
ATOM   8732  C CE1 . HIS C 1 186 ? -39.061 75.703  55.754 1.00 89.99  ? 194 HIS C CE1 1 
ATOM   8733  N NE2 . HIS C 1 186 ? -38.116 74.872  55.370 1.00 71.14  ? 194 HIS C NE2 1 
ATOM   8734  N N   . PRO C 1 187 ? -43.893 71.040  54.455 1.00 64.75  ? 195 PRO C N   1 
ATOM   8735  C CA  . PRO C 1 187 ? -44.842 70.229  53.670 1.00 80.40  ? 195 PRO C CA  1 
ATOM   8736  C C   . PRO C 1 187 ? -45.711 71.170  52.870 1.00 67.56  ? 195 PRO C C   1 
ATOM   8737  O O   . PRO C 1 187 ? -45.978 72.255  53.393 1.00 77.82  ? 195 PRO C O   1 
ATOM   8738  C CB  . PRO C 1 187 ? -45.713 69.480  54.703 1.00 84.02  ? 195 PRO C CB  1 
ATOM   8739  C CG  . PRO C 1 187 ? -45.538 70.277  55.992 1.00 77.94  ? 195 PRO C CG  1 
ATOM   8740  C CD  . PRO C 1 187 ? -44.111 70.868  55.899 1.00 80.80  ? 195 PRO C CD  1 
ATOM   8741  N N   . LYS C 1 188 ? -46.056 70.774  51.623 1.00 48.86  ? 196 LYS C N   1 
ATOM   8742  C CA  . LYS C 1 188 ? -46.914 71.578  50.751 1.00 56.48  ? 196 LYS C CA  1 
ATOM   8743  C C   . LYS C 1 188 ? -48.353 71.188  51.123 1.00 77.03  ? 196 LYS C C   1 
ATOM   8744  O O   . LYS C 1 188 ? -49.303 71.986  50.980 1.00 72.53  ? 196 LYS C O   1 
ATOM   8745  C CB  . LYS C 1 188 ? -46.690 71.354  49.252 1.00 49.03  ? 196 LYS C CB  1 
ATOM   8746  C CG  . LYS C 1 188 ? -45.644 72.104  48.422 1.00 74.16  ? 196 LYS C CG  1 
ATOM   8747  C CD  . LYS C 1 188 ? -46.003 73.374  47.651 1.00 100.05 ? 196 LYS C CD  1 
ATOM   8748  C CE  . LYS C 1 188 ? -46.310 73.247  46.170 1.00 74.14  ? 196 LYS C CE  1 
ATOM   8749  N NZ  . LYS C 1 188 ? -46.932 74.491  45.661 1.00 63.13  ? 196 LYS C NZ  1 
ATOM   8750  N N   . LEU C 1 189 ? -48.473 69.933  51.614 1.00 66.62  ? 197 LEU C N   1 
ATOM   8751  C CA  . LEU C 1 189 ? -49.749 69.340  51.992 1.00 62.95  ? 197 LEU C CA  1 
ATOM   8752  C C   . LEU C 1 189 ? -49.565 68.363  53.167 1.00 59.05  ? 197 LEU C C   1 
ATOM   8753  O O   . LEU C 1 189 ? -48.620 67.563  53.199 1.00 56.13  ? 197 LEU C O   1 
ATOM   8754  C CB  . LEU C 1 189 ? -50.346 68.695  50.746 1.00 43.72  ? 197 LEU C CB  1 
ATOM   8755  C CG  . LEU C 1 189 ? -51.722 68.046  50.956 1.00 58.43  ? 197 LEU C CG  1 
ATOM   8756  C CD1 . LEU C 1 189 ? -52.534 68.023  49.615 1.00 57.41  ? 197 LEU C CD1 1 
ATOM   8757  C CD2 . LEU C 1 189 ? -51.715 66.635  51.573 1.00 44.22  ? 197 LEU C CD2 1 
ATOM   8758  N N   . ILE C 1 190 ? -50.468 68.447  54.149 1.00 44.30  ? 198 ILE C N   1 
ATOM   8759  C CA  . ILE C 1 190 ? -50.406 67.565  55.303 1.00 51.04  ? 198 ILE C CA  1 
ATOM   8760  C C   . ILE C 1 190 ? -51.715 66.777  55.349 1.00 70.89  ? 198 ILE C C   1 
ATOM   8761  O O   . ILE C 1 190 ? -52.817 67.366  55.338 1.00 87.73  ? 198 ILE C O   1 
ATOM   8762  C CB  . ILE C 1 190 ? -50.269 68.303  56.645 1.00 45.31  ? 198 ILE C CB  1 
ATOM   8763  C CG1 . ILE C 1 190 ? -49.199 69.380  56.683 1.00 63.45  ? 198 ILE C CG1 1 
ATOM   8764  C CG2 . ILE C 1 190 ? -50.076 67.257  57.738 1.00 33.84  ? 198 ILE C CG2 1 
ATOM   8765  C CD1 . ILE C 1 190 ? -49.112 70.105  58.039 1.00 45.30  ? 198 ILE C CD1 1 
ATOM   8766  N N   . ILE C 1 191 ? -51.584 65.449  55.484 1.00 51.81  ? 199 ILE C N   1 
ATOM   8767  C CA  . ILE C 1 191 ? -52.736 64.579  55.451 1.00 48.96  ? 199 ILE C CA  1 
ATOM   8768  C C   . ILE C 1 191 ? -53.244 64.328  56.873 1.00 62.37  ? 199 ILE C C   1 
ATOM   8769  O O   . ILE C 1 191 ? -52.494 63.945  57.777 1.00 83.71  ? 199 ILE C O   1 
ATOM   8770  C CB  . ILE C 1 191 ? -52.311 63.293  54.736 1.00 63.87  ? 199 ILE C CB  1 
ATOM   8771  C CG1 . ILE C 1 191 ? -51.812 63.577  53.353 1.00 76.50  ? 199 ILE C CG1 1 
ATOM   8772  C CG2 . ILE C 1 191 ? -53.403 62.227  54.715 1.00 86.51  ? 199 ILE C CG2 1 
ATOM   8773  C CD1 . ILE C 1 191 ? -51.099 62.382  52.755 1.00 97.13  ? 199 ILE C CD1 1 
ATOM   8774  N N   . ALA C 1 192 ? -54.558 64.487  57.053 1.00 72.56  ? 200 ALA C N   1 
ATOM   8775  C CA  . ALA C 1 192 ? -55.235 64.211  58.310 1.00 80.88  ? 200 ALA C CA  1 
ATOM   8776  C C   . ALA C 1 192 ? -56.184 63.036  58.077 1.00 94.49  ? 200 ALA C C   1 
ATOM   8777  O O   . ALA C 1 192 ? -57.330 63.189  57.647 1.00 78.90  ? 200 ALA C O   1 
ATOM   8778  C CB  . ALA C 1 192 ? -55.970 65.451  58.753 1.00 89.26  ? 200 ALA C CB  1 
ATOM   8779  N N   . GLY C 1 193 ? -55.670 61.835  58.325 1.00 115.22 ? 201 GLY C N   1 
ATOM   8780  C CA  . GLY C 1 193 ? -56.397 60.639  57.930 1.00 89.76  ? 201 GLY C CA  1 
ATOM   8781  C C   . GLY C 1 193 ? -55.615 59.408  58.334 1.00 98.30  ? 201 GLY C C   1 
ATOM   8782  O O   . GLY C 1 193 ? -54.371 59.461  58.357 1.00 132.15 ? 201 GLY C O   1 
ATOM   8783  N N   . THR C 1 194 ? -56.369 58.367  58.728 1.00 73.21  ? 202 THR C N   1 
ATOM   8784  C CA  . THR C 1 194 ? -55.739 57.148  59.228 1.00 93.69  ? 202 THR C CA  1 
ATOM   8785  C C   . THR C 1 194 ? -56.381 55.897  58.617 1.00 105.75 ? 202 THR C C   1 
ATOM   8786  O O   . THR C 1 194 ? -57.513 55.929  58.117 1.00 77.67  ? 202 THR C O   1 
ATOM   8787  C CB  . THR C 1 194 ? -55.692 57.085  60.757 1.00 84.17  ? 202 THR C CB  1 
ATOM   8788  O OG1 . THR C 1 194 ? -57.022 56.807  61.151 1.00 92.24  ? 202 THR C OG1 1 
ATOM   8789  C CG2 . THR C 1 194 ? -55.298 58.394  61.433 1.00 62.11  ? 202 THR C CG2 1 
ATOM   8790  N N   . SER C 1 195 ? -55.621 54.791  58.648 1.00 105.73 ? 203 SER C N   1 
ATOM   8791  C CA  . SER C 1 195 ? -56.208 53.513  58.295 1.00 89.39  ? 203 SER C CA  1 
ATOM   8792  C C   . SER C 1 195 ? -56.338 52.633  59.535 1.00 90.37  ? 203 SER C C   1 
ATOM   8793  O O   . SER C 1 195 ? -57.020 51.616  59.521 1.00 98.56  ? 203 SER C O   1 
ATOM   8794  C CB  . SER C 1 195 ? -55.451 52.827  57.215 1.00 111.50 ? 203 SER C CB  1 
ATOM   8795  O OG  . SER C 1 195 ? -56.425 52.170  56.403 1.00 119.95 ? 203 SER C OG  1 
ATOM   8796  N N   . CYS C 1 196 ? -55.632 53.014  60.597 1.00 110.27 ? 204 CYS C N   1 
ATOM   8797  C CA  . CYS C 1 196 ? -55.687 52.240  61.816 1.00 99.30  ? 204 CYS C CA  1 
ATOM   8798  C C   . CYS C 1 196 ? -55.357 53.128  63.013 1.00 86.34  ? 204 CYS C C   1 
ATOM   8799  O O   . CYS C 1 196 ? -54.230 53.085  63.499 1.00 58.31  ? 204 CYS C O   1 
ATOM   8800  C CB  . CYS C 1 196 ? -54.663 51.112  61.777 1.00 86.24  ? 204 CYS C CB  1 
ATOM   8801  S SG  . CYS C 1 196 ? -54.921 49.952  63.142 1.00 69.54  ? 204 CYS C SG  1 
ATOM   8802  N N   . TYR C 1 197 ? -56.356 53.865  63.521 1.00 80.90  ? 205 TYR C N   1 
ATOM   8803  C CA  . TYR C 1 197 ? -56.177 54.674  64.720 1.00 81.17  ? 205 TYR C CA  1 
ATOM   8804  C C   . TYR C 1 197 ? -57.498 54.764  65.478 1.00 88.16  ? 205 TYR C C   1 
ATOM   8805  O O   . TYR C 1 197 ? -58.528 55.026  64.893 1.00 67.83  ? 205 TYR C O   1 
ATOM   8806  C CB  . TYR C 1 197 ? -55.671 56.024  64.203 1.00 66.81  ? 205 TYR C CB  1 
ATOM   8807  C CG  . TYR C 1 197 ? -55.241 57.034  65.241 1.00 68.21  ? 205 TYR C CG  1 
ATOM   8808  C CD1 . TYR C 1 197 ? -54.047 56.863  65.954 1.00 93.02  ? 205 TYR C CD1 1 
ATOM   8809  C CD2 . TYR C 1 197 ? -55.933 58.221  65.410 1.00 59.96  ? 205 TYR C CD2 1 
ATOM   8810  C CE1 . TYR C 1 197 ? -53.590 57.821  66.860 1.00 80.44  ? 205 TYR C CE1 1 
ATOM   8811  C CE2 . TYR C 1 197 ? -55.508 59.189  66.318 1.00 72.01  ? 205 TYR C CE2 1 
ATOM   8812  C CZ  . TYR C 1 197 ? -54.349 58.978  67.053 1.00 80.83  ? 205 TYR C CZ  1 
ATOM   8813  O OH  . TYR C 1 197 ? -53.984 59.953  67.926 1.00 77.54  ? 205 TYR C OH  1 
ATOM   8814  N N   . SER C 1 198 ? -57.500 54.493  66.788 1.00 123.01 ? 206 SER C N   1 
ATOM   8815  C CA  . SER C 1 198 ? -58.744 54.336  67.542 1.00 99.99  ? 206 SER C CA  1 
ATOM   8816  C C   . SER C 1 198 ? -59.343 55.687  67.901 1.00 84.79  ? 206 SER C C   1 
ATOM   8817  O O   . SER C 1 198 ? -60.411 55.697  68.499 1.00 88.28  ? 206 SER C O   1 
ATOM   8818  C CB  . SER C 1 198 ? -58.505 53.608  68.843 1.00 100.66 ? 206 SER C CB  1 
ATOM   8819  O OG  . SER C 1 198 ? -58.005 52.280  68.686 1.00 93.17  ? 206 SER C OG  1 
ATOM   8820  N N   . ARG C 1 199 ? -58.644 56.795  67.582 1.00 77.74  ? 207 ARG C N   1 
ATOM   8821  C CA  . ARG C 1 199 ? -58.956 58.080  68.196 1.00 80.89  ? 207 ARG C CA  1 
ATOM   8822  C C   . ARG C 1 199 ? -59.274 59.136  67.156 1.00 73.07  ? 207 ARG C C   1 
ATOM   8823  O O   . ARG C 1 199 ? -58.969 58.955  65.991 1.00 77.93  ? 207 ARG C O   1 
ATOM   8824  C CB  . ARG C 1 199 ? -57.819 58.614  69.067 1.00 66.37  ? 207 ARG C CB  1 
ATOM   8825  C CG  . ARG C 1 199 ? -57.606 57.718  70.274 1.00 67.90  ? 207 ARG C CG  1 
ATOM   8826  C CD  . ARG C 1 199 ? -58.881 57.572  71.051 1.00 84.59  ? 207 ARG C CD  1 
ATOM   8827  N NE  . ARG C 1 199 ? -58.550 56.831  72.260 1.00 112.58 ? 207 ARG C NE  1 
ATOM   8828  C CZ  . ARG C 1 199 ? -59.413 56.404  73.169 1.00 94.64  ? 207 ARG C CZ  1 
ATOM   8829  N NH1 . ARG C 1 199 ? -60.679 56.737  73.145 1.00 95.24  ? 207 ARG C NH1 1 
ATOM   8830  N NH2 . ARG C 1 199 ? -58.975 55.675  74.162 1.00 78.77  ? 207 ARG C NH2 1 
ATOM   8831  N N   . ASN C 1 200 ? -59.906 60.237  67.600 1.00 62.41  ? 208 ASN C N   1 
ATOM   8832  C CA  . ASN C 1 200 ? -60.181 61.342  66.709 1.00 79.84  ? 208 ASN C CA  1 
ATOM   8833  C C   . ASN C 1 200 ? -58.891 62.081  66.390 1.00 68.23  ? 208 ASN C C   1 
ATOM   8834  O O   . ASN C 1 200 ? -57.920 62.002  67.122 1.00 62.38  ? 208 ASN C O   1 
ATOM   8835  C CB  . ASN C 1 200 ? -61.245 62.270  67.268 1.00 83.65  ? 208 ASN C CB  1 
ATOM   8836  C CG  . ASN C 1 200 ? -62.568 61.558  67.401 1.00 66.02  ? 208 ASN C CG  1 
ATOM   8837  O OD1 . ASN C 1 200 ? -62.919 60.626  66.676 1.00 67.78  ? 208 ASN C OD1 1 
ATOM   8838  N ND2 . ASN C 1 200 ? -63.309 61.903  68.414 1.00 69.39  ? 208 ASN C ND2 1 
ATOM   8839  N N   . LEU C 1 201 ? -58.857 62.795  65.270 1.00 65.01  ? 209 LEU C N   1 
ATOM   8840  C CA  . LEU C 1 201 ? -57.671 63.607  65.028 1.00 57.71  ? 209 LEU C CA  1 
ATOM   8841  C C   . LEU C 1 201 ? -57.922 64.999  65.583 1.00 61.43  ? 209 LEU C C   1 
ATOM   8842  O O   . LEU C 1 201 ? -59.018 65.549  65.360 1.00 96.41  ? 209 LEU C O   1 
ATOM   8843  C CB  . LEU C 1 201 ? -57.454 63.729  63.522 1.00 35.19  ? 209 LEU C CB  1 
ATOM   8844  C CG  . LEU C 1 201 ? -57.182 62.419  62.813 1.00 25.81  ? 209 LEU C CG  1 
ATOM   8845  C CD1 . LEU C 1 201 ? -56.897 62.780  61.308 1.00 21.64  ? 209 LEU C CD1 1 
ATOM   8846  C CD2 . LEU C 1 201 ? -56.083 61.541  63.473 1.00 21.07  ? 209 LEU C CD2 1 
ATOM   8847  N N   . GLU C 1 202 ? -56.858 65.591  66.136 1.00 51.14  ? 210 GLU C N   1 
ATOM   8848  C CA  . GLU C 1 202 ? -56.832 67.030  66.374 1.00 81.28  ? 210 GLU C CA  1 
ATOM   8849  C C   . GLU C 1 202 ? -56.833 67.795  65.038 1.00 83.70  ? 210 GLU C C   1 
ATOM   8850  O O   . GLU C 1 202 ? -55.820 68.399  64.732 1.00 99.52  ? 210 GLU C O   1 
ATOM   8851  C CB  . GLU C 1 202 ? -55.583 67.321  67.228 1.00 69.06  ? 210 GLU C CB  1 
ATOM   8852  C CG  . GLU C 1 202 ? -55.643 66.831  68.672 1.00 73.24  ? 210 GLU C CG  1 
ATOM   8853  C CD  . GLU C 1 202 ? -54.686 67.492  69.660 1.00 110.05 ? 210 GLU C CD  1 
ATOM   8854  O OE1 . GLU C 1 202 ? -54.326 68.717  69.575 1.00 107.49 ? 210 GLU C OE1 1 
ATOM   8855  O OE2 . GLU C 1 202 ? -54.345 66.758  70.626 1.00 96.55  ? 210 GLU C OE2 1 
ATOM   8856  N N   . TYR C 1 203 ? -57.926 67.777  64.240 1.00 71.72  ? 211 TYR C N   1 
ATOM   8857  C CA  . TYR C 1 203 ? -58.023 68.608  63.026 1.00 85.78  ? 211 TYR C CA  1 
ATOM   8858  C C   . TYR C 1 203 ? -57.605 70.069  63.311 1.00 89.24  ? 211 TYR C C   1 
ATOM   8859  O O   . TYR C 1 203 ? -56.749 70.664  62.641 1.00 62.53  ? 211 TYR C O   1 
ATOM   8860  C CB  . TYR C 1 203 ? -59.393 68.560  62.313 1.00 66.18  ? 211 TYR C CB  1 
ATOM   8861  C CG  . TYR C 1 203 ? -59.839 67.149  61.961 1.00 75.21  ? 211 TYR C CG  1 
ATOM   8862  C CD1 . TYR C 1 203 ? -59.186 66.457  60.955 1.00 103.68 ? 211 TYR C CD1 1 
ATOM   8863  C CD2 . TYR C 1 203 ? -60.904 66.517  62.583 1.00 104.13 ? 211 TYR C CD2 1 
ATOM   8864  C CE1 . TYR C 1 203 ? -59.562 65.180  60.572 1.00 101.69 ? 211 TYR C CE1 1 
ATOM   8865  C CE2 . TYR C 1 203 ? -61.284 65.232  62.217 1.00 128.77 ? 211 TYR C CE2 1 
ATOM   8866  C CZ  . TYR C 1 203 ? -60.605 64.553  61.213 1.00 107.70 ? 211 TYR C CZ  1 
ATOM   8867  O OH  . TYR C 1 203 ? -60.925 63.291  60.785 1.00 73.05  ? 211 TYR C OH  1 
ATOM   8868  N N   . ALA C 1 204 ? -58.278 70.655  64.310 1.00 86.47  ? 212 ALA C N   1 
ATOM   8869  C CA  . ALA C 1 204 ? -57.926 71.852  65.040 1.00 75.92  ? 212 ALA C CA  1 
ATOM   8870  C C   . ALA C 1 204 ? -56.411 72.182  64.942 1.00 86.93  ? 212 ALA C C   1 
ATOM   8871  O O   . ALA C 1 204 ? -55.956 73.186  64.324 1.00 79.84  ? 212 ALA C O   1 
ATOM   8872  C CB  . ALA C 1 204 ? -58.322 71.402  66.442 1.00 78.29  ? 212 ALA C CB  1 
ATOM   8873  N N   . ARG C 1 205 ? -55.610 71.328  65.606 1.00 77.18  ? 213 ARG C N   1 
ATOM   8874  C CA  . ARG C 1 205 ? -54.166 71.514  65.725 1.00 71.42  ? 213 ARG C CA  1 
ATOM   8875  C C   . ARG C 1 205 ? -53.489 71.294  64.380 1.00 80.10  ? 213 ARG C C   1 
ATOM   8876  O O   . ARG C 1 205 ? -52.597 72.045  64.001 1.00 84.38  ? 213 ARG C O   1 
ATOM   8877  C CB  . ARG C 1 205 ? -53.469 70.531  66.664 1.00 70.80  ? 213 ARG C CB  1 
ATOM   8878  C CG  . ARG C 1 205 ? -52.085 71.008  67.081 1.00 56.88  ? 213 ARG C CG  1 
ATOM   8879  C CD  . ARG C 1 205 ? -51.750 70.278  68.460 1.00 84.63  ? 213 ARG C CD  1 
ATOM   8880  N NE  . ARG C 1 205 ? -50.347 70.199  68.921 1.00 68.34  ? 213 ARG C NE  1 
ATOM   8881  C CZ  . ARG C 1 205 ? -49.380 71.027  68.437 1.00 81.61  ? 213 ARG C CZ  1 
ATOM   8882  N NH1 . ARG C 1 205 ? -49.628 71.988  67.502 1.00 73.93  ? 213 ARG C NH1 1 
ATOM   8883  N NH2 . ARG C 1 205 ? -48.146 70.910  68.919 1.00 48.99  ? 213 ARG C NH2 1 
ATOM   8884  N N   . LEU C 1 206 ? -53.932 70.286  63.631 1.00 62.43  ? 214 LEU C N   1 
ATOM   8885  C CA  . LEU C 1 206 ? -53.361 70.048  62.310 1.00 65.64  ? 214 LEU C CA  1 
ATOM   8886  C C   . LEU C 1 206 ? -53.523 71.285  61.445 1.00 74.42  ? 214 LEU C C   1 
ATOM   8887  O O   . LEU C 1 206 ? -52.660 71.607  60.641 1.00 98.59  ? 214 LEU C O   1 
ATOM   8888  C CB  . LEU C 1 206 ? -53.997 68.851  61.615 1.00 61.99  ? 214 LEU C CB  1 
ATOM   8889  C CG  . LEU C 1 206 ? -53.670 67.541  62.326 1.00 69.83  ? 214 LEU C CG  1 
ATOM   8890  C CD1 . LEU C 1 206 ? -54.563 66.436  61.802 1.00 57.64  ? 214 LEU C CD1 1 
ATOM   8891  C CD2 . LEU C 1 206 ? -52.129 67.285  62.287 1.00 59.85  ? 214 LEU C CD2 1 
ATOM   8892  N N   . ARG C 1 207 ? -54.660 71.961  61.592 1.00 84.78  ? 215 ARG C N   1 
ATOM   8893  C CA  . ARG C 1 207 ? -54.894 73.108  60.741 1.00 82.22  ? 215 ARG C CA  1 
ATOM   8894  C C   . ARG C 1 207 ? -53.954 74.239  61.142 1.00 85.50  ? 215 ARG C C   1 
ATOM   8895  O O   . ARG C 1 207 ? -53.398 74.907  60.230 1.00 72.88  ? 215 ARG C O   1 
ATOM   8896  C CB  . ARG C 1 207 ? -56.342 73.582  60.771 1.00 66.40  ? 215 ARG C CB  1 
ATOM   8897  C CG  . ARG C 1 207 ? -56.472 74.864  59.975 1.00 67.65  ? 215 ARG C CG  1 
ATOM   8898  C CD  . ARG C 1 207 ? -56.579 74.975  58.469 1.00 62.20  ? 215 ARG C CD  1 
ATOM   8899  N NE  . ARG C 1 207 ? -57.046 76.364  58.428 1.00 52.75  ? 215 ARG C NE  1 
ATOM   8900  C CZ  . ARG C 1 207 ? -57.405 76.990  57.358 1.00 77.58  ? 215 ARG C CZ  1 
ATOM   8901  N NH1 . ARG C 1 207 ? -56.600 76.939  56.311 1.00 90.48  ? 215 ARG C NH1 1 
ATOM   8902  N NH2 . ARG C 1 207 ? -58.422 77.820  57.432 1.00 93.07  ? 215 ARG C NH2 1 
ATOM   8903  N N   . LYS C 1 208 ? -53.800 74.432  62.481 1.00 55.54  ? 216 LYS C N   1 
ATOM   8904  C CA  . LYS C 1 208 ? -52.825 75.401  62.976 1.00 64.73  ? 216 LYS C CA  1 
ATOM   8905  C C   . LYS C 1 208 ? -51.471 75.116  62.290 1.00 83.60  ? 216 LYS C C   1 
ATOM   8906  O O   . LYS C 1 208 ? -50.906 75.995  61.611 1.00 88.55  ? 216 LYS C O   1 
ATOM   8907  C CB  . LYS C 1 208 ? -52.871 75.535  64.504 1.00 49.77  ? 216 LYS C CB  1 
ATOM   8908  C CG  . LYS C 1 208 ? -54.291 75.529  65.234 1.00 81.25  ? 216 LYS C CG  1 
ATOM   8909  C CD  . LYS C 1 208 ? -54.487 75.169  66.745 1.00 75.85  ? 216 LYS C CD  1 
ATOM   8910  C CE  . LYS C 1 208 ? -55.714 75.282  67.710 1.00 50.64  ? 216 LYS C CE  1 
ATOM   8911  N NZ  . LYS C 1 208 ? -55.501 74.673  69.024 1.00 35.32  ? 216 LYS C NZ  1 
ATOM   8912  N N   . ILE C 1 209 ? -51.027 73.840  62.338 1.00 60.96  ? 217 ILE C N   1 
ATOM   8913  C CA  . ILE C 1 209 ? -49.696 73.523  61.835 1.00 69.32  ? 217 ILE C CA  1 
ATOM   8914  C C   . ILE C 1 209 ? -49.605 73.758  60.341 1.00 75.69  ? 217 ILE C C   1 
ATOM   8915  O O   . ILE C 1 209 ? -48.541 74.172  59.897 1.00 76.91  ? 217 ILE C O   1 
ATOM   8916  C CB  . ILE C 1 209 ? -49.144 72.126  62.169 1.00 60.71  ? 217 ILE C CB  1 
ATOM   8917  C CG1 . ILE C 1 209 ? -49.387 71.732  63.593 1.00 55.22  ? 217 ILE C CG1 1 
ATOM   8918  C CG2 . ILE C 1 209 ? -47.636 72.105  61.849 1.00 44.06  ? 217 ILE C CG2 1 
ATOM   8919  C CD1 . ILE C 1 209 ? -48.543 70.542  63.993 1.00 37.88  ? 217 ILE C CD1 1 
ATOM   8920  N N   . ALA C 1 210 ? -50.663 73.421  59.591 1.00 69.82  ? 218 ALA C N   1 
ATOM   8921  C CA  . ALA C 1 210 ? -50.658 73.614  58.148 1.00 78.08  ? 218 ALA C CA  1 
ATOM   8922  C C   . ALA C 1 210 ? -50.510 75.102  57.836 1.00 84.18  ? 218 ALA C C   1 
ATOM   8923  O O   . ALA C 1 210 ? -49.569 75.503  57.143 1.00 75.64  ? 218 ALA C O   1 
ATOM   8924  C CB  . ALA C 1 210 ? -51.875 73.017  57.485 1.00 66.78  ? 218 ALA C CB  1 
ATOM   8925  N N   . ASP C 1 211 ? -51.371 75.915  58.455 1.00 88.05  ? 219 ASP C N   1 
ATOM   8926  C CA  . ASP C 1 211 ? -51.344 77.342  58.172 1.00 81.93  ? 219 ASP C CA  1 
ATOM   8927  C C   . ASP C 1 211 ? -49.996 77.908  58.559 1.00 65.36  ? 219 ASP C C   1 
ATOM   8928  O O   . ASP C 1 211 ? -49.466 78.732  57.846 1.00 72.34  ? 219 ASP C O   1 
ATOM   8929  C CB  . ASP C 1 211 ? -52.428 78.115  58.895 1.00 78.58  ? 219 ASP C CB  1 
ATOM   8930  C CG  . ASP C 1 211 ? -53.813 77.732  58.436 1.00 91.64  ? 219 ASP C CG  1 
ATOM   8931  O OD1 . ASP C 1 211 ? -53.994 77.482  57.211 1.00 111.00 ? 219 ASP C OD1 1 
ATOM   8932  O OD2 . ASP C 1 211 ? -54.673 77.677  59.302 1.00 73.08  ? 219 ASP C OD2 1 
ATOM   8933  N N   . GLU C 1 212 ? -49.430 77.407  59.653 1.00 53.85  ? 220 GLU C N   1 
ATOM   8934  C CA  . GLU C 1 212 ? -48.140 77.893  60.102 1.00 66.08  ? 220 GLU C CA  1 
ATOM   8935  C C   . GLU C 1 212 ? -47.103 77.723  58.995 1.00 66.50  ? 220 GLU C C   1 
ATOM   8936  O O   . GLU C 1 212 ? -46.180 78.517  58.940 1.00 72.19  ? 220 GLU C O   1 
ATOM   8937  C CB  . GLU C 1 212 ? -47.727 77.228  61.423 1.00 64.77  ? 220 GLU C CB  1 
ATOM   8938  C CG  . GLU C 1 212 ? -46.464 77.805  62.052 1.00 74.33  ? 220 GLU C CG  1 
ATOM   8939  C CD  . GLU C 1 212 ? -45.512 76.791  62.666 1.00 104.32 ? 220 GLU C CD  1 
ATOM   8940  O OE1 . GLU C 1 212 ? -45.694 75.531  62.748 1.00 111.98 ? 220 GLU C OE1 1 
ATOM   8941  O OE2 . GLU C 1 212 ? -44.465 77.352  63.052 1.00 103.74 ? 220 GLU C OE2 1 
ATOM   8942  N N   . ASN C 1 213 ? -47.241 76.673  58.166 1.00 77.37  ? 221 ASN C N   1 
ATOM   8943  C CA  . ASN C 1 213 ? -46.235 76.294  57.190 1.00 82.87  ? 221 ASN C CA  1 
ATOM   8944  C C   . ASN C 1 213 ? -46.704 76.602  55.779 1.00 93.39  ? 221 ASN C C   1 
ATOM   8945  O O   . ASN C 1 213 ? -45.977 76.285  54.834 1.00 110.70 ? 221 ASN C O   1 
ATOM   8946  C CB  . ASN C 1 213 ? -45.933 74.810  57.277 1.00 83.58  ? 221 ASN C CB  1 
ATOM   8947  C CG  . ASN C 1 213 ? -45.130 74.518  58.518 1.00 100.50 ? 221 ASN C CG  1 
ATOM   8948  O OD1 . ASN C 1 213 ? -43.904 74.676  58.479 1.00 93.38  ? 221 ASN C OD1 1 
ATOM   8949  N ND2 . ASN C 1 213 ? -45.775 74.070  59.594 1.00 97.05  ? 221 ASN C ND2 1 
ATOM   8950  N N   . GLY C 1 214 ? -47.901 77.203  55.671 1.00 81.95  ? 222 GLY C N   1 
ATOM   8951  C CA  . GLY C 1 214 ? -48.441 77.657  54.403 1.00 56.72  ? 222 GLY C CA  1 
ATOM   8952  C C   . GLY C 1 214 ? -48.785 76.460  53.540 1.00 55.69  ? 222 GLY C C   1 
ATOM   8953  O O   . GLY C 1 214 ? -48.531 76.505  52.351 1.00 51.05  ? 222 GLY C O   1 
ATOM   8954  N N   . ALA C 1 215 ? -49.170 75.355  54.181 1.00 75.31  ? 223 ALA C N   1 
ATOM   8955  C CA  . ALA C 1 215 ? -49.519 74.135  53.455 1.00 67.03  ? 223 ALA C CA  1 
ATOM   8956  C C   . ALA C 1 215 ? -51.012 73.896  53.555 1.00 82.89  ? 223 ALA C C   1 
ATOM   8957  O O   . ALA C 1 215 ? -51.699 74.516  54.365 1.00 97.03  ? 223 ALA C O   1 
ATOM   8958  C CB  . ALA C 1 215 ? -48.887 72.913  54.095 1.00 90.59  ? 223 ALA C CB  1 
ATOM   8959  N N   . TYR C 1 216 ? -51.472 72.947  52.730 1.00 90.53  ? 224 TYR C N   1 
ATOM   8960  C CA  . TYR C 1 216 ? -52.869 72.551  52.704 1.00 72.79  ? 224 TYR C CA  1 
ATOM   8961  C C   . TYR C 1 216 ? -53.100 71.509  53.782 1.00 78.67  ? 224 TYR C C   1 
ATOM   8962  O O   . TYR C 1 216 ? -52.195 70.708  54.052 1.00 125.18 ? 224 TYR C O   1 
ATOM   8963  C CB  . TYR C 1 216 ? -53.004 71.762  51.408 1.00 68.19  ? 224 TYR C CB  1 
ATOM   8964  C CG  . TYR C 1 216 ? -53.266 72.611  50.183 1.00 74.46  ? 224 TYR C CG  1 
ATOM   8965  C CD1 . TYR C 1 216 ? -54.390 73.408  50.096 1.00 62.52  ? 224 TYR C CD1 1 
ATOM   8966  C CD2 . TYR C 1 216 ? -52.431 72.553  49.088 1.00 83.17  ? 224 TYR C CD2 1 
ATOM   8967  C CE1 . TYR C 1 216 ? -54.685 74.122  48.955 1.00 48.25  ? 224 TYR C CE1 1 
ATOM   8968  C CE2 . TYR C 1 216 ? -52.689 73.303  47.954 1.00 75.98  ? 224 TYR C CE2 1 
ATOM   8969  C CZ  . TYR C 1 216 ? -53.814 74.090  47.895 1.00 60.02  ? 224 TYR C CZ  1 
ATOM   8970  O OH  . TYR C 1 216 ? -54.010 74.802  46.761 1.00 94.10  ? 224 TYR C OH  1 
ATOM   8971  N N   . LEU C 1 217 ? -54.323 71.480  54.326 1.00 73.76  ? 225 LEU C N   1 
ATOM   8972  C CA  . LEU C 1 217 ? -54.693 70.395  55.229 1.00 88.45  ? 225 LEU C CA  1 
ATOM   8973  C C   . LEU C 1 217 ? -55.712 69.512  54.528 1.00 84.50  ? 225 LEU C C   1 
ATOM   8974  O O   . LEU C 1 217 ? -56.852 69.902  54.302 1.00 103.57 ? 225 LEU C O   1 
ATOM   8975  C CB  . LEU C 1 217 ? -55.256 70.908  56.544 1.00 105.70 ? 225 LEU C CB  1 
ATOM   8976  C CG  . LEU C 1 217 ? -55.619 69.822  57.555 1.00 99.17  ? 225 LEU C CG  1 
ATOM   8977  C CD1 . LEU C 1 217 ? -54.302 69.288  58.021 1.00 99.02  ? 225 LEU C CD1 1 
ATOM   8978  C CD2 . LEU C 1 217 ? -56.509 70.358  58.698 1.00 89.01  ? 225 LEU C CD2 1 
ATOM   8979  N N   . MET C 1 218 ? -55.259 68.346  54.110 1.00 82.40  ? 226 MET C N   1 
ATOM   8980  C CA  . MET C 1 218 ? -56.126 67.437  53.382 1.00 73.64  ? 226 MET C CA  1 
ATOM   8981  C C   . MET C 1 218 ? -56.485 66.286  54.317 1.00 69.46  ? 226 MET C C   1 
ATOM   8982  O O   . MET C 1 218 ? -55.623 65.606  54.886 1.00 63.19  ? 226 MET C O   1 
ATOM   8983  C CB  . MET C 1 218 ? -55.438 66.827  52.156 1.00 67.65  ? 226 MET C CB  1 
ATOM   8984  C CG  . MET C 1 218 ? -56.296 65.794  51.483 1.00 72.10  ? 226 MET C CG  1 
ATOM   8985  S SD  . MET C 1 218 ? -55.322 64.831  50.313 1.00 81.52  ? 226 MET C SD  1 
ATOM   8986  C CE  . MET C 1 218 ? -55.252 63.385  51.373 1.00 120.04 ? 226 MET C CE  1 
ATOM   8987  N N   . ALA C 1 219 ? -57.786 66.067  54.467 1.00 55.35  ? 227 ALA C N   1 
ATOM   8988  C CA  . ALA C 1 219 ? -58.229 65.001  55.333 1.00 53.58  ? 227 ALA C CA  1 
ATOM   8989  C C   . ALA C 1 219 ? -58.556 63.798  54.463 1.00 73.67  ? 227 ALA C C   1 
ATOM   8990  O O   . ALA C 1 219 ? -59.144 63.969  53.392 1.00 80.21  ? 227 ALA C O   1 
ATOM   8991  C CB  . ALA C 1 219 ? -59.451 65.492  56.051 1.00 51.48  ? 227 ALA C CB  1 
ATOM   8992  N N   . ASP C 1 220 ? -58.153 62.603  54.913 1.00 77.58  ? 228 ASP C N   1 
ATOM   8993  C CA  . ASP C 1 220 ? -58.587 61.359  54.285 1.00 76.64  ? 228 ASP C CA  1 
ATOM   8994  C C   . ASP C 1 220 ? -59.530 60.668  55.264 1.00 78.88  ? 228 ASP C C   1 
ATOM   8995  O O   . ASP C 1 220 ? -59.077 60.002  56.189 1.00 90.44  ? 228 ASP C O   1 
ATOM   8996  C CB  . ASP C 1 220 ? -57.415 60.510  53.801 1.00 68.07  ? 228 ASP C CB  1 
ATOM   8997  C CG  . ASP C 1 220 ? -57.753 59.228  53.055 1.00 80.35  ? 228 ASP C CG  1 
ATOM   8998  O OD1 . ASP C 1 220 ? -58.920 58.841  53.026 1.00 100.57 ? 228 ASP C OD1 1 
ATOM   8999  O OD2 . ASP C 1 220 ? -56.860 58.643  52.425 1.00 80.48  ? 228 ASP C OD2 1 
ATOM   9000  N N   . MET C 1 221 ? -60.834 60.820  55.037 1.00 75.30  ? 229 MET C N   1 
ATOM   9001  C CA  . MET C 1 221 ? -61.824 60.308  55.984 1.00 99.12  ? 229 MET C CA  1 
ATOM   9002  C C   . MET C 1 221 ? -62.307 58.907  55.593 1.00 93.30  ? 229 MET C C   1 
ATOM   9003  O O   . MET C 1 221 ? -63.361 58.480  56.052 1.00 83.20  ? 229 MET C O   1 
ATOM   9004  C CB  . MET C 1 221 ? -63.045 61.238  56.123 1.00 84.73  ? 229 MET C CB  1 
ATOM   9005  C CG  . MET C 1 221 ? -63.840 61.394  54.838 1.00 93.00  ? 229 MET C CG  1 
ATOM   9006  S SD  . MET C 1 221 ? -65.322 62.421  54.905 1.00 104.81 ? 229 MET C SD  1 
ATOM   9007  C CE  . MET C 1 221 ? -66.238 61.523  56.159 1.00 139.00 ? 229 MET C CE  1 
ATOM   9008  N N   . ALA C 1 222 ? -61.529 58.206  54.756 1.00 88.11  ? 230 ALA C N   1 
ATOM   9009  C CA  . ALA C 1 222 ? -61.921 56.933  54.160 1.00 88.03  ? 230 ALA C CA  1 
ATOM   9010  C C   . ALA C 1 222 ? -62.517 56.001  55.189 1.00 74.75  ? 230 ALA C C   1 
ATOM   9011  O O   . ALA C 1 222 ? -63.593 55.443  54.909 1.00 73.47  ? 230 ALA C O   1 
ATOM   9012  C CB  . ALA C 1 222 ? -60.759 56.244  53.498 1.00 107.43 ? 230 ALA C CB  1 
ATOM   9013  N N   . HIS C 1 223 ? -61.798 55.848  56.329 1.00 65.70  ? 231 HIS C N   1 
ATOM   9014  C CA  . HIS C 1 223 ? -62.198 54.874  57.341 1.00 74.71  ? 231 HIS C CA  1 
ATOM   9015  C C   . HIS C 1 223 ? -63.438 55.299  58.117 1.00 80.34  ? 231 HIS C C   1 
ATOM   9016  O O   . HIS C 1 223 ? -64.173 54.442  58.597 1.00 97.94  ? 231 HIS C O   1 
ATOM   9017  C CB  . HIS C 1 223 ? -61.087 54.544  58.336 1.00 73.62  ? 231 HIS C CB  1 
ATOM   9018  C CG  . HIS C 1 223 ? -60.519 53.194  58.150 1.00 88.88  ? 231 HIS C CG  1 
ATOM   9019  N ND1 . HIS C 1 223 ? -59.610 52.864  57.168 1.00 110.51 ? 231 HIS C ND1 1 
ATOM   9020  C CD2 . HIS C 1 223 ? -60.800 52.083  58.809 1.00 82.40  ? 231 HIS C CD2 1 
ATOM   9021  C CE1 . HIS C 1 223 ? -59.313 51.583  57.263 1.00 95.63  ? 231 HIS C CE1 1 
ATOM   9022  N NE2 . HIS C 1 223 ? -60.022 51.089  58.252 1.00 110.07 ? 231 HIS C NE2 1 
ATOM   9023  N N   . ILE C 1 224 ? -63.669 56.612  58.232 1.00 68.80  ? 232 ILE C N   1 
ATOM   9024  C CA  . ILE C 1 224 ? -64.658 57.126  59.156 1.00 70.59  ? 232 ILE C CA  1 
ATOM   9025  C C   . ILE C 1 224 ? -65.704 57.924  58.380 1.00 81.47  ? 232 ILE C C   1 
ATOM   9026  O O   . ILE C 1 224 ? -66.457 58.683  59.000 1.00 88.33  ? 232 ILE C O   1 
ATOM   9027  C CB  . ILE C 1 224 ? -63.960 57.972  60.233 1.00 75.29  ? 232 ILE C CB  1 
ATOM   9028  C CG1 . ILE C 1 224 ? -63.444 59.313  59.664 1.00 64.30  ? 232 ILE C CG1 1 
ATOM   9029  C CG2 . ILE C 1 224 ? -62.880 57.166  60.991 1.00 69.90  ? 232 ILE C CG2 1 
ATOM   9030  C CD1 . ILE C 1 224 ? -62.911 60.261  60.746 1.00 64.16  ? 232 ILE C CD1 1 
ATOM   9031  N N   . SER C 1 225 ? -65.769 57.722  57.053 1.00 75.28  ? 233 SER C N   1 
ATOM   9032  C CA  . SER C 1 225 ? -66.714 58.465  56.218 1.00 73.46  ? 233 SER C CA  1 
ATOM   9033  C C   . SER C 1 225 ? -68.120 58.347  56.774 1.00 72.30  ? 233 SER C C   1 
ATOM   9034  O O   . SER C 1 225 ? -68.804 59.353  56.921 1.00 110.12 ? 233 SER C O   1 
ATOM   9035  C CB  . SER C 1 225 ? -66.665 58.148  54.736 1.00 61.34  ? 233 SER C CB  1 
ATOM   9036  O OG  . SER C 1 225 ? -66.439 56.775  54.469 1.00 59.77  ? 233 SER C OG  1 
ATOM   9037  N N   . GLY C 1 226 ? -68.533 57.121  57.083 1.00 56.66  ? 234 GLY C N   1 
ATOM   9038  C CA  . GLY C 1 226 ? -69.856 56.892  57.651 1.00 63.37  ? 234 GLY C CA  1 
ATOM   9039  C C   . GLY C 1 226 ? -70.005 57.494  59.047 1.00 73.77  ? 234 GLY C C   1 
ATOM   9040  O O   . GLY C 1 226 ? -71.064 57.972  59.423 1.00 62.71  ? 234 GLY C O   1 
ATOM   9041  N N   . LEU C 1 227 ? -68.944 57.423  59.846 1.00 90.10  ? 235 LEU C N   1 
ATOM   9042  C CA  . LEU C 1 227 ? -68.998 57.934  61.209 1.00 98.14  ? 235 LEU C CA  1 
ATOM   9043  C C   . LEU C 1 227 ? -69.237 59.440  61.140 1.00 100.57 ? 235 LEU C C   1 
ATOM   9044  O O   . LEU C 1 227 ? -70.057 59.977  61.881 1.00 105.91 ? 235 LEU C O   1 
ATOM   9045  C CB  . LEU C 1 227 ? -67.716 57.615  61.972 1.00 88.44  ? 235 LEU C CB  1 
ATOM   9046  C CG  . LEU C 1 227 ? -67.367 56.125  62.110 1.00 84.69  ? 235 LEU C CG  1 
ATOM   9047  C CD1 . LEU C 1 227 ? -66.286 56.036  63.135 1.00 128.23 ? 235 LEU C CD1 1 
ATOM   9048  C CD2 . LEU C 1 227 ? -68.450 55.186  62.542 1.00 65.39  ? 235 LEU C CD2 1 
ATOM   9049  N N   . VAL C 1 228 ? -68.560 60.093  60.193 1.00 85.10  ? 236 VAL C N   1 
ATOM   9050  C CA  . VAL C 1 228 ? -68.641 61.537  60.088 1.00 75.99  ? 236 VAL C CA  1 
ATOM   9051  C C   . VAL C 1 228 ? -70.028 61.935  59.599 1.00 57.56  ? 236 VAL C C   1 
ATOM   9052  O O   . VAL C 1 228 ? -70.654 62.805  60.176 1.00 51.07  ? 236 VAL C O   1 
ATOM   9053  C CB  . VAL C 1 228 ? -67.511 62.098  59.216 1.00 76.72  ? 236 VAL C CB  1 
ATOM   9054  C CG1 . VAL C 1 228 ? -67.734 63.543  58.872 1.00 69.62  ? 236 VAL C CG1 1 
ATOM   9055  C CG2 . VAL C 1 228 ? -66.174 62.016  59.916 1.00 80.27  ? 236 VAL C CG2 1 
ATOM   9056  N N   . ALA C 1 229 ? -70.524 61.255  58.575 1.00 49.61  ? 237 ALA C N   1 
ATOM   9057  C CA  . ALA C 1 229 ? -71.877 61.454  58.050 1.00 56.08  ? 237 ALA C CA  1 
ATOM   9058  C C   . ALA C 1 229 ? -72.928 61.344  59.155 1.00 50.03  ? 237 ALA C C   1 
ATOM   9059  O O   . ALA C 1 229 ? -73.901 62.060  59.109 1.00 50.36  ? 237 ALA C O   1 
ATOM   9060  C CB  . ALA C 1 229 ? -72.189 60.466  56.917 1.00 46.27  ? 237 ALA C CB  1 
ATOM   9061  N N   . ALA C 1 230 ? -72.799 60.414  60.108 1.00 56.25  ? 238 ALA C N   1 
ATOM   9062  C CA  . ALA C 1 230 ? -73.791 60.264  61.176 1.00 68.57  ? 238 ALA C CA  1 
ATOM   9063  C C   . ALA C 1 230 ? -73.527 61.239  62.321 1.00 67.55  ? 238 ALA C C   1 
ATOM   9064  O O   . ALA C 1 230 ? -74.329 61.311  63.245 1.00 102.09 ? 238 ALA C O   1 
ATOM   9065  C CB  . ALA C 1 230 ? -73.852 58.846  61.701 1.00 63.75  ? 238 ALA C CB  1 
ATOM   9066  N N   . GLY C 1 231 ? -72.408 61.968  62.244 1.00 68.84  ? 239 GLY C N   1 
ATOM   9067  C CA  . GLY C 1 231 ? -72.003 62.927  63.263 1.00 64.06  ? 239 GLY C CA  1 
ATOM   9068  C C   . GLY C 1 231 ? -71.619 62.248  64.576 1.00 70.59  ? 239 GLY C C   1 
ATOM   9069  O O   . GLY C 1 231 ? -71.766 62.882  65.605 1.00 81.51  ? 239 GLY C O   1 
ATOM   9070  N N   . VAL C 1 232 ? -71.134 60.991  64.536 1.00 63.88  ? 240 VAL C N   1 
ATOM   9071  C CA  . VAL C 1 232 ? -70.741 60.196  65.692 1.00 59.43  ? 240 VAL C CA  1 
ATOM   9072  C C   . VAL C 1 232 ? -69.272 60.496  66.007 1.00 72.19  ? 240 VAL C C   1 
ATOM   9073  O O   . VAL C 1 232 ? -68.759 60.115  67.036 1.00 116.22 ? 240 VAL C O   1 
ATOM   9074  C CB  . VAL C 1 232 ? -70.930 58.728  65.216 1.00 79.69  ? 240 VAL C CB  1 
ATOM   9075  C CG1 . VAL C 1 232 ? -69.956 57.664  65.751 1.00 66.53  ? 240 VAL C CG1 1 
ATOM   9076  C CG2 . VAL C 1 232 ? -72.375 58.262  65.274 1.00 88.24  ? 240 VAL C CG2 1 
ATOM   9077  N N   . VAL C 1 233 ? -68.577 61.161  65.097 1.00 78.94  ? 241 VAL C N   1 
ATOM   9078  C CA  . VAL C 1 233 ? -67.222 61.618  65.283 1.00 74.82  ? 241 VAL C CA  1 
ATOM   9079  C C   . VAL C 1 233 ? -67.067 62.970  64.603 1.00 76.91  ? 241 VAL C C   1 
ATOM   9080  O O   . VAL C 1 233 ? -67.682 63.193  63.539 1.00 79.36  ? 241 VAL C O   1 
ATOM   9081  C CB  . VAL C 1 233 ? -66.351 60.623  64.530 1.00 92.73  ? 241 VAL C CB  1 
ATOM   9082  C CG1 . VAL C 1 233 ? -65.093 61.296  63.947 1.00 87.14  ? 241 VAL C CG1 1 
ATOM   9083  C CG2 . VAL C 1 233 ? -66.090 59.432  65.433 1.00 109.31 ? 241 VAL C CG2 1 
ATOM   9084  N N   . PRO C 1 234 ? -66.265 63.874  65.229 1.00 56.86  ? 242 PRO C N   1 
ATOM   9085  C CA  . PRO C 1 234 ? -66.090 65.247  64.749 1.00 47.85  ? 242 PRO C CA  1 
ATOM   9086  C C   . PRO C 1 234 ? -65.662 65.246  63.306 1.00 57.39  ? 242 PRO C C   1 
ATOM   9087  O O   . PRO C 1 234 ? -64.822 64.428  62.915 1.00 89.28  ? 242 PRO C O   1 
ATOM   9088  C CB  . PRO C 1 234 ? -65.079 65.889  65.683 1.00 46.98  ? 242 PRO C CB  1 
ATOM   9089  C CG  . PRO C 1 234 ? -65.409 65.132  66.974 1.00 47.74  ? 242 PRO C CG  1 
ATOM   9090  C CD  . PRO C 1 234 ? -65.576 63.660  66.510 1.00 67.50  ? 242 PRO C CD  1 
ATOM   9091  N N   . SER C 1 235 ? -66.237 66.200  62.554 1.00 72.42  ? 243 SER C N   1 
ATOM   9092  C CA  . SER C 1 235 ? -66.041 66.292  61.111 1.00 79.62  ? 243 SER C CA  1 
ATOM   9093  C C   . SER C 1 235 ? -64.752 67.038  60.703 1.00 85.09  ? 243 SER C C   1 
ATOM   9094  O O   . SER C 1 235 ? -64.354 68.091  61.241 1.00 90.34  ? 243 SER C O   1 
ATOM   9095  C CB  . SER C 1 235 ? -67.233 66.931  60.500 1.00 91.01  ? 243 SER C CB  1 
ATOM   9096  O OG  . SER C 1 235 ? -66.964 67.207  59.137 1.00 78.30  ? 243 SER C OG  1 
ATOM   9097  N N   . PRO C 1 236 ? -63.999 66.493  59.724 1.00 95.47  ? 244 PRO C N   1 
ATOM   9098  C CA  . PRO C 1 236 ? -62.791 67.185  59.272 1.00 101.65 ? 244 PRO C CA  1 
ATOM   9099  C C   . PRO C 1 236 ? -63.139 68.407  58.424 1.00 101.47 ? 244 PRO C C   1 
ATOM   9100  O O   . PRO C 1 236 ? -62.243 69.219  58.151 1.00 78.01  ? 244 PRO C O   1 
ATOM   9101  C CB  . PRO C 1 236 ? -62.156 66.088  58.430 1.00 83.96  ? 244 PRO C CB  1 
ATOM   9102  C CG  . PRO C 1 236 ? -63.370 65.378  57.818 1.00 95.65  ? 244 PRO C CG  1 
ATOM   9103  C CD  . PRO C 1 236 ? -64.243 65.196  59.048 1.00 84.26  ? 244 PRO C CD  1 
ATOM   9104  N N   . PHE C 1 237 ? -64.429 68.519  58.021 1.00 64.06  ? 245 PHE C N   1 
ATOM   9105  C CA  . PHE C 1 237 ? -64.839 69.575  57.111 1.00 70.06  ? 245 PHE C CA  1 
ATOM   9106  C C   . PHE C 1 237 ? -64.634 70.949  57.743 1.00 71.76  ? 245 PHE C C   1 
ATOM   9107  O O   . PHE C 1 237 ? -64.540 71.969  57.031 1.00 69.79  ? 245 PHE C O   1 
ATOM   9108  C CB  . PHE C 1 237 ? -66.244 69.410  56.551 1.00 54.83  ? 245 PHE C CB  1 
ATOM   9109  C CG  . PHE C 1 237 ? -66.301 68.289  55.540 1.00 58.45  ? 245 PHE C CG  1 
ATOM   9110  C CD1 . PHE C 1 237 ? -65.889 68.464  54.206 1.00 65.74  ? 245 PHE C CD1 1 
ATOM   9111  C CD2 . PHE C 1 237 ? -66.792 67.057  55.945 1.00 60.65  ? 245 PHE C CD2 1 
ATOM   9112  C CE1 . PHE C 1 237 ? -65.934 67.400  53.297 1.00 66.39  ? 245 PHE C CE1 1 
ATOM   9113  C CE2 . PHE C 1 237 ? -66.857 65.993  55.046 1.00 85.55  ? 245 PHE C CE2 1 
ATOM   9114  C CZ  . PHE C 1 237 ? -66.429 66.166  53.728 1.00 92.99  ? 245 PHE C CZ  1 
ATOM   9115  N N   . GLU C 1 238 ? -64.528 70.936  59.073 1.00 63.65  ? 246 GLU C N   1 
ATOM   9116  C CA  . GLU C 1 238 ? -64.566 72.187  59.791 1.00 76.88  ? 246 GLU C CA  1 
ATOM   9117  C C   . GLU C 1 238 ? -63.208 72.886  59.730 1.00 91.85  ? 246 GLU C C   1 
ATOM   9118  O O   . GLU C 1 238 ? -63.158 74.102  59.846 1.00 146.03 ? 246 GLU C O   1 
ATOM   9119  C CB  . GLU C 1 238 ? -64.976 71.881  61.222 1.00 86.00  ? 246 GLU C CB  1 
ATOM   9120  C CG  . GLU C 1 238 ? -65.353 73.138  61.995 1.00 94.59  ? 246 GLU C CG  1 
ATOM   9121  C CD  . GLU C 1 238 ? -65.177 73.071  63.513 1.00 99.14  ? 246 GLU C CD  1 
ATOM   9122  O OE1 . GLU C 1 238 ? -64.775 74.082  64.131 1.00 92.60  ? 246 GLU C OE1 1 
ATOM   9123  O OE2 . GLU C 1 238 ? -65.339 71.986  64.100 1.00 90.35  ? 246 GLU C OE2 1 
ATOM   9124  N N   . HIS C 1 239 ? -62.112 72.143  59.500 1.00 97.57  ? 247 HIS C N   1 
ATOM   9125  C CA  . HIS C 1 239 ? -60.776 72.737  59.487 1.00 90.21  ? 247 HIS C CA  1 
ATOM   9126  C C   . HIS C 1 239 ? -60.019 72.511  58.176 1.00 89.55  ? 247 HIS C C   1 
ATOM   9127  O O   . HIS C 1 239 ? -59.161 73.319  57.849 1.00 80.08  ? 247 HIS C O   1 
ATOM   9128  C CB  . HIS C 1 239 ? -59.900 72.160  60.599 1.00 87.99  ? 247 HIS C CB  1 
ATOM   9129  C CG  . HIS C 1 239 ? -60.617 72.193  61.889 1.00 97.17  ? 247 HIS C CG  1 
ATOM   9130  N ND1 . HIS C 1 239 ? -60.376 73.205  62.782 1.00 83.66  ? 247 HIS C ND1 1 
ATOM   9131  C CD2 . HIS C 1 239 ? -61.574 71.430  62.425 1.00 109.54 ? 247 HIS C CD2 1 
ATOM   9132  C CE1 . HIS C 1 239 ? -61.098 73.029  63.869 1.00 86.20  ? 247 HIS C CE1 1 
ATOM   9133  N NE2 . HIS C 1 239 ? -61.907 72.013  63.625 1.00 133.19 ? 247 HIS C NE2 1 
ATOM   9134  N N   . CYS C 1 240 ? -60.344 71.445  57.422 1.00 70.71  ? 248 CYS C N   1 
ATOM   9135  C CA  . CYS C 1 240 ? -59.534 71.056  56.275 1.00 64.26  ? 248 CYS C CA  1 
ATOM   9136  C C   . CYS C 1 240 ? -59.888 71.811  54.985 1.00 59.95  ? 248 CYS C C   1 
ATOM   9137  O O   . CYS C 1 240 ? -61.008 72.301  54.791 1.00 74.25  ? 248 CYS C O   1 
ATOM   9138  C CB  . CYS C 1 240 ? -59.673 69.562  56.070 1.00 72.07  ? 248 CYS C CB  1 
ATOM   9139  S SG  . CYS C 1 240 ? -59.049 68.667  57.509 1.00 82.16  ? 248 CYS C SG  1 
ATOM   9140  N N   . HIS C 1 241 ? -58.906 71.911  54.081 1.00 51.37  ? 249 HIS C N   1 
ATOM   9141  C CA  . HIS C 1 241 ? -59.117 72.578  52.802 1.00 64.48  ? 249 HIS C CA  1 
ATOM   9142  C C   . HIS C 1 241 ? -59.776 71.613  51.842 1.00 67.26  ? 249 HIS C C   1 
ATOM   9143  O O   . HIS C 1 241 ? -60.600 72.009  51.006 1.00 73.09  ? 249 HIS C O   1 
ATOM   9144  C CB  . HIS C 1 241 ? -57.806 73.045  52.158 1.00 52.97  ? 249 HIS C CB  1 
ATOM   9145  C CG  . HIS C 1 241 ? -57.132 74.078  53.016 1.00 70.07  ? 249 HIS C CG  1 
ATOM   9146  N ND1 . HIS C 1 241 ? -56.140 73.791  53.941 1.00 71.95  ? 249 HIS C ND1 1 
ATOM   9147  C CD2 . HIS C 1 241 ? -57.389 75.412  53.107 1.00 57.89  ? 249 HIS C CD2 1 
ATOM   9148  C CE1 . HIS C 1 241 ? -55.770 74.926  54.515 1.00 83.31  ? 249 HIS C CE1 1 
ATOM   9149  N NE2 . HIS C 1 241 ? -56.527 75.913  54.046 1.00 75.02  ? 249 HIS C NE2 1 
ATOM   9150  N N   . VAL C 1 242 ? -59.350 70.355  51.973 1.00 61.12  ? 250 VAL C N   1 
ATOM   9151  C CA  . VAL C 1 242 ? -59.830 69.299  51.098 1.00 68.09  ? 250 VAL C CA  1 
ATOM   9152  C C   . VAL C 1 242 ? -60.027 68.040  51.928 1.00 77.92  ? 250 VAL C C   1 
ATOM   9153  O O   . VAL C 1 242 ? -59.269 67.786  52.870 1.00 79.33  ? 250 VAL C O   1 
ATOM   9154  C CB  . VAL C 1 242 ? -58.789 69.069  49.999 1.00 67.42  ? 250 VAL C CB  1 
ATOM   9155  C CG1 . VAL C 1 242 ? -59.029 67.785  49.244 1.00 70.90  ? 250 VAL C CG1 1 
ATOM   9156  C CG2 . VAL C 1 242 ? -58.795 70.216  49.022 1.00 63.24  ? 250 VAL C CG2 1 
ATOM   9157  N N   . VAL C 1 243 ? -61.059 67.266  51.556 1.00 61.01  ? 251 VAL C N   1 
ATOM   9158  C CA  . VAL C 1 243 ? -61.320 66.005  52.219 1.00 74.34  ? 251 VAL C CA  1 
ATOM   9159  C C   . VAL C 1 243 ? -61.532 64.929  51.162 1.00 91.41  ? 251 VAL C C   1 
ATOM   9160  O O   . VAL C 1 243 ? -62.460 65.045  50.355 1.00 106.15 ? 251 VAL C O   1 
ATOM   9161  C CB  . VAL C 1 243 ? -62.550 66.121  53.134 1.00 80.71  ? 251 VAL C CB  1 
ATOM   9162  C CG1 . VAL C 1 243 ? -62.859 64.776  53.769 1.00 84.67  ? 251 VAL C CG1 1 
ATOM   9163  C CG2 . VAL C 1 243 ? -62.350 67.179  54.209 1.00 79.87  ? 251 VAL C CG2 1 
ATOM   9164  N N   . THR C 1 244 ? -60.704 63.869  51.213 1.00 71.04  ? 252 THR C N   1 
ATOM   9165  C CA  . THR C 1 244 ? -60.861 62.759  50.279 1.00 71.09  ? 252 THR C CA  1 
ATOM   9166  C C   . THR C 1 244 ? -61.512 61.602  51.022 1.00 66.74  ? 252 THR C C   1 
ATOM   9167  O O   . THR C 1 244 ? -61.432 61.540  52.247 1.00 68.72  ? 252 THR C O   1 
ATOM   9168  C CB  . THR C 1 244 ? -59.532 62.336  49.648 1.00 66.67  ? 252 THR C CB  1 
ATOM   9169  O OG1 . THR C 1 244 ? -58.630 62.015  50.696 1.00 56.90  ? 252 THR C OG1 1 
ATOM   9170  C CG2 . THR C 1 244 ? -58.849 63.395  48.810 1.00 56.12  ? 252 THR C CG2 1 
ATOM   9171  N N   . THR C 1 245 ? -62.129 60.684  50.279 1.00 59.95  ? 253 THR C N   1 
ATOM   9172  C CA  . THR C 1 245 ? -62.722 59.521  50.927 1.00 75.63  ? 253 THR C CA  1 
ATOM   9173  C C   . THR C 1 245 ? -62.899 58.334  49.983 1.00 73.28  ? 253 THR C C   1 
ATOM   9174  O O   . THR C 1 245 ? -63.026 58.492  48.782 1.00 90.42  ? 253 THR C O   1 
ATOM   9175  C CB  . THR C 1 245 ? -64.091 59.929  51.449 1.00 57.16  ? 253 THR C CB  1 
ATOM   9176  O OG1 . THR C 1 245 ? -64.386 58.852  52.355 1.00 48.73  ? 253 THR C OG1 1 
ATOM   9177  C CG2 . THR C 1 245 ? -65.059 60.030  50.277 1.00 50.38  ? 253 THR C CG2 1 
ATOM   9178  N N   . THR C 1 246 ? -63.007 57.159  50.567 1.00 59.45  ? 254 THR C N   1 
ATOM   9179  C CA  . THR C 1 246 ? -63.519 55.974  49.924 1.00 78.85  ? 254 THR C CA  1 
ATOM   9180  C C   . THR C 1 246 ? -65.043 55.886  50.119 1.00 97.70  ? 254 THR C C   1 
ATOM   9181  O O   . THR C 1 246 ? -65.584 56.220  51.193 1.00 98.36  ? 254 THR C O   1 
ATOM   9182  C CB  . THR C 1 246 ? -62.750 54.887  50.674 1.00 89.12  ? 254 THR C CB  1 
ATOM   9183  O OG1 . THR C 1 246 ? -62.835 53.652  49.978 1.00 123.11 ? 254 THR C OG1 1 
ATOM   9184  C CG2 . THR C 1 246 ? -63.121 54.841  52.154 1.00 66.45  ? 254 THR C CG2 1 
ATOM   9185  N N   . THR C 1 247 ? -65.741 55.374  49.089 1.00 85.82  ? 255 THR C N   1 
ATOM   9186  C CA  . THR C 1 247 ? -67.194 55.284  49.121 1.00 81.61  ? 255 THR C CA  1 
ATOM   9187  C C   . THR C 1 247 ? -67.648 53.952  49.726 1.00 87.86  ? 255 THR C C   1 
ATOM   9188  O O   . THR C 1 247 ? -68.831 53.806  50.027 1.00 75.62  ? 255 THR C O   1 
ATOM   9189  C CB  . THR C 1 247 ? -67.823 55.488  47.733 1.00 99.63  ? 255 THR C CB  1 
ATOM   9190  O OG1 . THR C 1 247 ? -67.288 54.533  46.817 1.00 111.32 ? 255 THR C OG1 1 
ATOM   9191  C CG2 . THR C 1 247 ? -67.646 56.887  47.179 1.00 95.42  ? 255 THR C CG2 1 
ATOM   9192  N N   . HIS C 1 248 ? -66.737 52.974  49.864 1.00 81.51  ? 256 HIS C N   1 
ATOM   9193  C CA  . HIS C 1 248 ? -67.007 51.818  50.713 1.00 108.61 ? 256 HIS C CA  1 
ATOM   9194  C C   . HIS C 1 248 ? -66.567 52.051  52.173 1.00 110.00 ? 256 HIS C C   1 
ATOM   9195  O O   . HIS C 1 248 ? -66.701 53.164  52.737 1.00 70.56  ? 256 HIS C O   1 
ATOM   9196  C CB  . HIS C 1 248 ? -66.378 50.577  50.081 1.00 116.32 ? 256 HIS C CB  1 
ATOM   9197  C CG  . HIS C 1 248 ? -64.962 50.733  49.619 1.00 102.09 ? 256 HIS C CG  1 
ATOM   9198  N ND1 . HIS C 1 248 ? -64.471 51.421  48.527 1.00 81.92  ? 256 HIS C ND1 1 
ATOM   9199  C CD2 . HIS C 1 248 ? -63.893 50.184  50.225 1.00 98.23  ? 256 HIS C CD2 1 
ATOM   9200  C CE1 . HIS C 1 248 ? -63.138 51.267  48.491 1.00 116.21 ? 256 HIS C CE1 1 
ATOM   9201  N NE2 . HIS C 1 248 ? -62.767 50.525  49.517 1.00 104.36 ? 256 HIS C NE2 1 
ATOM   9202  N N   . LYS C 1 249 ? -66.070 50.972  52.806 1.00 83.87  ? 257 LYS C N   1 
ATOM   9203  C CA  . LYS C 1 249 ? -65.837 51.009  54.244 1.00 105.91 ? 257 LYS C CA  1 
ATOM   9204  C C   . LYS C 1 249 ? -67.103 51.464  54.986 1.00 102.07 ? 257 LYS C C   1 
ATOM   9205  O O   . LYS C 1 249 ? -68.202 50.977  54.718 1.00 79.32  ? 257 LYS C O   1 
ATOM   9206  C CB  . LYS C 1 249 ? -64.587 51.845  54.523 1.00 101.26 ? 257 LYS C CB  1 
ATOM   9207  C CG  . LYS C 1 249 ? -63.393 51.340  53.755 1.00 88.39  ? 257 LYS C CG  1 
ATOM   9208  C CD  . LYS C 1 249 ? -62.014 51.887  54.134 1.00 96.63  ? 257 LYS C CD  1 
ATOM   9209  C CE  . LYS C 1 249 ? -61.045 51.261  53.132 1.00 94.05  ? 257 LYS C CE  1 
ATOM   9210  N NZ  . LYS C 1 249 ? -59.670 50.863  53.499 1.00 72.05  ? 257 LYS C NZ  1 
ATOM   9211  N N   . THR C 1 250 ? -66.956 52.407  55.927 1.00 108.89 ? 258 THR C N   1 
ATOM   9212  C CA  . THR C 1 250 ? -68.089 52.843  56.741 1.00 107.67 ? 258 THR C CA  1 
ATOM   9213  C C   . THR C 1 250 ? -69.184 53.580  55.951 1.00 98.00  ? 258 THR C C   1 
ATOM   9214  O O   . THR C 1 250 ? -70.253 53.866  56.498 1.00 82.02  ? 258 THR C O   1 
ATOM   9215  C CB  . THR C 1 250 ? -67.640 53.608  57.985 1.00 79.98  ? 258 THR C CB  1 
ATOM   9216  O OG1 . THR C 1 250 ? -66.787 54.679  57.563 1.00 52.38  ? 258 THR C OG1 1 
ATOM   9217  C CG2 . THR C 1 250 ? -66.954 52.681  58.970 1.00 95.55  ? 258 THR C CG2 1 
ATOM   9218  N N   . LEU C 1 251 ? -68.917 53.939  54.691 1.00 82.38  ? 259 LEU C N   1 
ATOM   9219  C CA  . LEU C 1 251 ? -69.934 54.632  53.916 1.00 91.72  ? 259 LEU C CA  1 
ATOM   9220  C C   . LEU C 1 251 ? -70.821 53.609  53.211 1.00 97.16  ? 259 LEU C C   1 
ATOM   9221  O O   . LEU C 1 251 ? -71.870 53.991  52.652 1.00 86.44  ? 259 LEU C O   1 
ATOM   9222  C CB  . LEU C 1 251 ? -69.336 55.633  52.932 1.00 96.37  ? 259 LEU C CB  1 
ATOM   9223  C CG  . LEU C 1 251 ? -70.272 56.798  52.558 1.00 98.47  ? 259 LEU C CG  1 
ATOM   9224  C CD1 . LEU C 1 251 ? -70.908 57.499  53.750 1.00 138.61 ? 259 LEU C CD1 1 
ATOM   9225  C CD2 . LEU C 1 251 ? -69.604 57.923  51.823 1.00 97.27  ? 259 LEU C CD2 1 
ATOM   9226  N N   . ARG C 1 252 ? -70.370 52.329  53.260 1.00 79.89  ? 260 ARG C N   1 
ATOM   9227  C CA  . ARG C 1 252 ? -71.141 51.141  52.887 1.00 65.99  ? 260 ARG C CA  1 
ATOM   9228  C C   . ARG C 1 252 ? -71.686 51.218  51.459 1.00 81.05  ? 260 ARG C C   1 
ATOM   9229  O O   . ARG C 1 252 ? -72.782 50.691  51.133 1.00 77.57  ? 260 ARG C O   1 
ATOM   9230  C CB  . ARG C 1 252 ? -72.338 50.939  53.818 1.00 62.77  ? 260 ARG C CB  1 
ATOM   9231  C CG  . ARG C 1 252 ? -72.439 49.453  54.116 1.00 75.32  ? 260 ARG C CG  1 
ATOM   9232  C CD  . ARG C 1 252 ? -73.344 49.217  55.310 1.00 85.41  ? 260 ARG C CD  1 
ATOM   9233  N NE  . ARG C 1 252 ? -74.643 49.890  55.242 1.00 80.74  ? 260 ARG C NE  1 
ATOM   9234  C CZ  . ARG C 1 252 ? -75.430 50.053  56.296 1.00 80.71  ? 260 ARG C CZ  1 
ATOM   9235  N NH1 . ARG C 1 252 ? -75.116 49.532  57.489 1.00 56.54  ? 260 ARG C NH1 1 
ATOM   9236  N NH2 . ARG C 1 252 ? -76.560 50.719  56.097 1.00 92.25  ? 260 ARG C NH2 1 
ATOM   9237  N N   . GLY C 1 253 ? -70.897 51.875  50.596 1.00 77.10  ? 261 GLY C N   1 
ATOM   9238  C CA  . GLY C 1 253 ? -71.224 51.910  49.183 1.00 86.81  ? 261 GLY C CA  1 
ATOM   9239  C C   . GLY C 1 253 ? -70.313 50.942  48.444 1.00 84.67  ? 261 GLY C C   1 
ATOM   9240  O O   . GLY C 1 253 ? -69.604 50.147  49.073 1.00 98.33  ? 261 GLY C O   1 
ATOM   9241  N N   . CYS C 1 254 ? -70.377 51.017  47.115 1.00 82.22  ? 262 CYS C N   1 
ATOM   9242  C CA  . CYS C 1 254 ? -69.504 50.222  46.272 1.00 96.81  ? 262 CYS C CA  1 
ATOM   9243  C C   . CYS C 1 254 ? -68.099 50.833  46.303 1.00 101.38 ? 262 CYS C C   1 
ATOM   9244  O O   . CYS C 1 254 ? -67.882 51.923  46.860 1.00 80.70  ? 262 CYS C O   1 
ATOM   9245  C CB  . CYS C 1 254 ? -70.067 50.115  44.862 1.00 87.13  ? 262 CYS C CB  1 
ATOM   9246  S SG  . CYS C 1 254 ? -70.368 51.729  44.102 1.00 101.79 ? 262 CYS C SG  1 
ATOM   9247  N N   . ARG C 1 255 ? -67.150 50.112  45.696 1.00 86.63  ? 263 ARG C N   1 
ATOM   9248  C CA  . ARG C 1 255 ? -65.777 50.590  45.707 1.00 82.41  ? 263 ARG C CA  1 
ATOM   9249  C C   . ARG C 1 255 ? -65.620 51.702  44.672 1.00 73.58  ? 263 ARG C C   1 
ATOM   9250  O O   . ARG C 1 255 ? -65.753 51.441  43.470 1.00 72.58  ? 263 ARG C O   1 
ATOM   9251  C CB  . ARG C 1 255 ? -64.820 49.420  45.459 1.00 85.22  ? 263 ARG C CB  1 
ATOM   9252  C CG  . ARG C 1 255 ? -64.761 48.408  46.590 1.00 73.92  ? 263 ARG C CG  1 
ATOM   9253  C CD  . ARG C 1 255 ? -63.833 47.248  46.164 1.00 88.18  ? 263 ARG C CD  1 
ATOM   9254  N NE  . ARG C 1 255 ? -63.682 46.316  47.288 1.00 72.14  ? 263 ARG C NE  1 
ATOM   9255  C CZ  . ARG C 1 255 ? -62.886 46.611  48.322 1.00 70.59  ? 263 ARG C CZ  1 
ATOM   9256  N NH1 . ARG C 1 255 ? -61.899 47.512  48.185 1.00 94.20  ? 263 ARG C NH1 1 
ATOM   9257  N NH2 . ARG C 1 255 ? -63.031 45.927  49.435 1.00 40.23  ? 263 ARG C NH2 1 
ATOM   9258  N N   . ALA C 1 256 ? -65.335 52.920  45.181 1.00 68.03  ? 264 ALA C N   1 
ATOM   9259  C CA  . ALA C 1 256 ? -65.018 54.149  44.451 1.00 78.84  ? 264 ALA C CA  1 
ATOM   9260  C C   . ALA C 1 256 ? -64.530 55.200  45.460 1.00 87.77  ? 264 ALA C C   1 
ATOM   9261  O O   . ALA C 1 256 ? -64.498 54.945  46.661 1.00 80.16  ? 264 ALA C O   1 
ATOM   9262  C CB  . ALA C 1 256 ? -66.224 54.647  43.642 1.00 86.24  ? 264 ALA C CB  1 
ATOM   9263  N N   . GLY C 1 257 ? -64.191 56.412  45.001 1.00 86.06  ? 265 GLY C N   1 
ATOM   9264  C CA  . GLY C 1 257 ? -63.736 57.456  45.912 1.00 72.43  ? 265 GLY C CA  1 
ATOM   9265  C C   . GLY C 1 257 ? -64.276 58.839  45.545 1.00 81.18  ? 265 GLY C C   1 
ATOM   9266  O O   . GLY C 1 257 ? -64.863 59.009  44.479 1.00 88.52  ? 265 GLY C O   1 
ATOM   9267  N N   . MET C 1 258 ? -64.056 59.827  46.427 1.00 65.92  ? 266 MET C N   1 
ATOM   9268  C CA  . MET C 1 258 ? -64.591 61.160  46.215 1.00 76.04  ? 266 MET C CA  1 
ATOM   9269  C C   . MET C 1 258 ? -63.615 62.198  46.732 1.00 70.81  ? 266 MET C C   1 
ATOM   9270  O O   . MET C 1 258 ? -62.918 61.908  47.691 1.00 72.93  ? 266 MET C O   1 
ATOM   9271  C CB  . MET C 1 258 ? -65.904 61.334  46.992 1.00 80.40  ? 266 MET C CB  1 
ATOM   9272  C CG  . MET C 1 258 ? -67.066 60.578  46.401 1.00 70.59  ? 266 MET C CG  1 
ATOM   9273  S SD  . MET C 1 258 ? -68.415 61.304  47.332 1.00 92.72  ? 266 MET C SD  1 
ATOM   9274  C CE  . MET C 1 258 ? -68.490 60.493  48.932 1.00 78.61  ? 266 MET C CE  1 
ATOM   9275  N N   . ILE C 1 259 ? -63.629 63.408  46.153 1.00 63.35  ? 267 ILE C N   1 
ATOM   9276  C CA  . ILE C 1 259 ? -62.771 64.489  46.639 1.00 70.66  ? 267 ILE C CA  1 
ATOM   9277  C C   . ILE C 1 259 ? -63.659 65.686  46.951 1.00 83.87  ? 267 ILE C C   1 
ATOM   9278  O O   . ILE C 1 259 ? -64.223 66.234  46.010 1.00 88.11  ? 267 ILE C O   1 
ATOM   9279  C CB  . ILE C 1 259 ? -61.684 64.869  45.601 1.00 76.66  ? 267 ILE C CB  1 
ATOM   9280  C CG1 . ILE C 1 259 ? -60.781 63.669  45.216 1.00 86.80  ? 267 ILE C CG1 1 
ATOM   9281  C CG2 . ILE C 1 259 ? -60.880 66.105  46.013 1.00 50.77  ? 267 ILE C CG2 1 
ATOM   9282  C CD1 . ILE C 1 259 ? -59.883 63.885  44.010 1.00 58.59  ? 267 ILE C CD1 1 
ATOM   9283  N N   . PHE C 1 260 ? -63.775 66.065  48.236 1.00 74.04  ? 268 PHE C N   1 
ATOM   9284  C CA  . PHE C 1 260 ? -64.422 67.317  48.626 1.00 80.33  ? 268 PHE C CA  1 
ATOM   9285  C C   . PHE C 1 260 ? -63.389 68.451  48.706 1.00 89.82  ? 268 PHE C C   1 
ATOM   9286  O O   . PHE C 1 260 ? -62.281 68.233  49.185 1.00 71.07  ? 268 PHE C O   1 
ATOM   9287  C CB  . PHE C 1 260 ? -65.104 67.167  49.984 1.00 76.95  ? 268 PHE C CB  1 
ATOM   9288  C CG  . PHE C 1 260 ? -66.188 66.099  50.016 1.00 92.51  ? 268 PHE C CG  1 
ATOM   9289  C CD1 . PHE C 1 260 ? -65.870 64.774  50.278 1.00 98.44  ? 268 PHE C CD1 1 
ATOM   9290  C CD2 . PHE C 1 260 ? -67.534 66.418  49.809 1.00 98.43  ? 268 PHE C CD2 1 
ATOM   9291  C CE1 . PHE C 1 260 ? -66.881 63.802  50.306 1.00 90.77  ? 268 PHE C CE1 1 
ATOM   9292  C CE2 . PHE C 1 260 ? -68.544 65.453  49.891 1.00 78.69  ? 268 PHE C CE2 1 
ATOM   9293  C CZ  . PHE C 1 260 ? -68.223 64.135  50.126 1.00 69.55  ? 268 PHE C CZ  1 
ATOM   9294  N N   . TYR C 1 261 ? -63.745 69.663  48.248 1.00 83.40  ? 269 TYR C N   1 
ATOM   9295  C CA  . TYR C 1 261 ? -62.801 70.777  48.203 1.00 96.53  ? 269 TYR C CA  1 
ATOM   9296  C C   . TYR C 1 261 ? -63.491 72.108  48.484 1.00 104.84 ? 269 TYR C C   1 
ATOM   9297  O O   . TYR C 1 261 ? -64.668 72.278  48.143 1.00 116.36 ? 269 TYR C O   1 
ATOM   9298  C CB  . TYR C 1 261 ? -62.142 70.883  46.825 1.00 99.70  ? 269 TYR C CB  1 
ATOM   9299  C CG  . TYR C 1 261 ? -63.121 70.698  45.677 1.00 106.85 ? 269 TYR C CG  1 
ATOM   9300  C CD1 . TYR C 1 261 ? -63.857 71.759  45.173 1.00 115.61 ? 269 TYR C CD1 1 
ATOM   9301  C CD2 . TYR C 1 261 ? -63.296 69.457  45.077 1.00 108.08 ? 269 TYR C CD2 1 
ATOM   9302  C CE1 . TYR C 1 261 ? -64.749 71.605  44.120 1.00 98.88  ? 269 TYR C CE1 1 
ATOM   9303  C CE2 . TYR C 1 261 ? -64.177 69.287  44.016 1.00 117.85 ? 269 TYR C CE2 1 
ATOM   9304  C CZ  . TYR C 1 261 ? -64.905 70.359  43.539 1.00 105.07 ? 269 TYR C CZ  1 
ATOM   9305  O OH  . TYR C 1 261 ? -65.739 70.164  42.486 1.00 121.14 ? 269 TYR C OH  1 
ATOM   9306  N N   . ARG C 1 262 ? -62.725 73.045  49.083 1.00 95.01  ? 270 ARG C N   1 
ATOM   9307  C CA  . ARG C 1 262 ? -63.247 74.350  49.491 1.00 110.03 ? 270 ARG C CA  1 
ATOM   9308  C C   . ARG C 1 262 ? -63.392 75.235  48.248 1.00 108.10 ? 270 ARG C C   1 
ATOM   9309  O O   . ARG C 1 262 ? -62.552 75.197  47.350 1.00 115.47 ? 270 ARG C O   1 
ATOM   9310  C CB  . ARG C 1 262 ? -62.531 75.054  50.667 1.00 110.64 ? 270 ARG C CB  1 
ATOM   9311  C CG  . ARG C 1 262 ? -63.460 75.987  51.445 1.00 107.49 ? 270 ARG C CG  1 
ATOM   9312  C CD  . ARG C 1 262 ? -63.016 76.803  52.659 1.00 73.18  ? 270 ARG C CD  1 
ATOM   9313  N NE  . ARG C 1 262 ? -62.678 75.907  53.782 1.00 101.11 ? 270 ARG C NE  1 
ATOM   9314  C CZ  . ARG C 1 262 ? -62.154 76.241  55.010 1.00 114.18 ? 270 ARG C CZ  1 
ATOM   9315  N NH1 . ARG C 1 262 ? -61.590 77.439  55.225 1.00 74.01  ? 270 ARG C NH1 1 
ATOM   9316  N NH2 . ARG C 1 262 ? -62.172 75.385  56.051 1.00 89.66  ? 270 ARG C NH2 1 
ATOM   9317  N N   . LYS C 1 263 ? -64.530 75.939  48.134 1.00 125.51 ? 271 LYS C N   1 
ATOM   9318  C CA  . LYS C 1 263 ? -64.705 76.953  47.098 1.00 118.29 ? 271 LYS C CA  1 
ATOM   9319  C C   . LYS C 1 263 ? -65.119 78.251  47.777 1.00 116.44 ? 271 LYS C C   1 
ATOM   9320  O O   . LYS C 1 263 ? -65.721 78.218  48.829 1.00 147.73 ? 271 LYS C O   1 
ATOM   9321  C CB  . LYS C 1 263 ? -65.774 76.647  46.038 1.00 100.72 ? 271 LYS C CB  1 
ATOM   9322  C CG  . LYS C 1 263 ? -66.450 75.276  45.948 1.00 76.07  ? 271 LYS C CG  1 
ATOM   9323  C CD  . LYS C 1 263 ? -66.867 74.998  44.507 1.00 65.48  ? 271 LYS C CD  1 
ATOM   9324  C CE  . LYS C 1 263 ? -68.324 75.214  44.280 1.00 62.91  ? 271 LYS C CE  1 
ATOM   9325  N NZ  . LYS C 1 263 ? -69.095 74.119  44.868 1.00 79.22  ? 271 LYS C NZ  1 
ATOM   9326  N N   . GLY C 1 264 ? -64.784 79.394  47.180 1.00 117.95 ? 272 GLY C N   1 
ATOM   9327  C CA  . GLY C 1 264 ? -65.186 80.671  47.748 1.00 105.91 ? 272 GLY C CA  1 
ATOM   9328  C C   . GLY C 1 264 ? -63.967 81.507  48.124 1.00 115.56 ? 272 GLY C C   1 
ATOM   9329  O O   . GLY C 1 264 ? -62.882 81.359  47.550 1.00 107.66 ? 272 GLY C O   1 
ATOM   9330  N N   . VAL C 1 265 ? -64.100 82.327  49.165 1.00 114.87 ? 273 VAL C N   1 
ATOM   9331  C CA  . VAL C 1 265 ? -62.982 83.243  49.528 1.00 109.37 ? 273 VAL C CA  1 
ATOM   9332  C C   . VAL C 1 265 ? -61.967 82.524  50.413 1.00 97.55  ? 273 VAL C C   1 
ATOM   9333  O O   . VAL C 1 265 ? -62.381 81.942  51.426 1.00 50.17  ? 273 VAL C O   1 
ATOM   9334  C CB  . VAL C 1 265 ? -63.505 84.514  50.215 1.00 108.87 ? 273 VAL C CB  1 
ATOM   9335  C CG1 . VAL C 1 265 ? -62.366 85.441  50.608 1.00 101.49 ? 273 VAL C CG1 1 
ATOM   9336  C CG2 . VAL C 1 265 ? -64.506 85.246  49.338 1.00 109.18 ? 273 VAL C CG2 1 
ATOM   9337  N N   . LYS C 1 266 ? -60.689 82.574  50.032 1.00 119.11 ? 274 LYS C N   1 
ATOM   9338  C CA  . LYS C 1 266 ? -59.613 81.987  50.864 1.00 88.25  ? 274 LYS C CA  1 
ATOM   9339  C C   . LYS C 1 266 ? -59.122 83.089  51.781 1.00 79.00  ? 274 LYS C C   1 
ATOM   9340  O O   . LYS C 1 266 ? -58.898 82.827  52.970 1.00 77.30  ? 274 LYS C O   1 
ATOM   9341  C CB  . LYS C 1 266 ? -58.427 81.557  50.004 1.00 78.80  ? 274 LYS C CB  1 
ATOM   9342  C CG  . LYS C 1 266 ? -57.258 80.948  50.765 1.00 59.44  ? 274 LYS C CG  1 
ATOM   9343  C CD  . LYS C 1 266 ? -56.017 80.761  49.920 1.00 75.75  ? 274 LYS C CD  1 
ATOM   9344  C CE  . LYS C 1 266 ? -55.370 82.070  49.519 1.00 102.98 ? 274 LYS C CE  1 
ATOM   9345  N NZ  . LYS C 1 266 ? -54.058 81.860  48.863 1.00 67.05  ? 274 LYS C NZ  1 
ATOM   9346  N N   . SER C 1 267 ? -58.971 84.280  51.218 1.00 77.62  ? 275 SER C N   1 
ATOM   9347  C CA  . SER C 1 267 ? -58.517 85.427  52.031 1.00 129.06 ? 275 SER C CA  1 
ATOM   9348  C C   . SER C 1 267 ? -58.811 86.731  51.296 1.00 154.37 ? 275 SER C C   1 
ATOM   9349  O O   . SER C 1 267 ? -58.747 86.733  50.057 1.00 152.43 ? 275 SER C O   1 
ATOM   9350  C CB  . SER C 1 267 ? -57.060 85.307  52.311 1.00 136.48 ? 275 SER C CB  1 
ATOM   9351  O OG  . SER C 1 267 ? -56.306 85.534  51.131 1.00 190.62 ? 275 SER C OG  1 
ATOM   9352  N N   . VAL C 1 268 ? -59.121 87.792  52.040 1.00 177.60 ? 276 VAL C N   1 
ATOM   9353  C CA  . VAL C 1 268 ? -59.340 89.124  51.412 1.00 164.95 ? 276 VAL C CA  1 
ATOM   9354  C C   . VAL C 1 268 ? -57.988 89.826  51.384 1.00 187.90 ? 276 VAL C C   1 
ATOM   9355  O O   . VAL C 1 268 ? -57.689 90.544  52.351 1.00 189.60 ? 276 VAL C O   1 
ATOM   9356  C CB  . VAL C 1 268 ? -60.371 89.953  52.193 1.00 132.98 ? 276 VAL C CB  1 
ATOM   9357  C CG1 . VAL C 1 268 ? -60.608 91.307  51.544 1.00 130.45 ? 276 VAL C CG1 1 
ATOM   9358  C CG2 . VAL C 1 268 ? -61.682 89.202  52.355 1.00 114.70 ? 276 VAL C CG2 1 
ATOM   9359  N N   . ASP C 1 269 ? -57.210 89.614  50.322 1.00 190.67 ? 277 ASP C N   1 
ATOM   9360  C CA  . ASP C 1 269 ? -55.845 90.193  50.254 1.00 210.84 ? 277 ASP C CA  1 
ATOM   9361  C C   . ASP C 1 269 ? -55.794 91.465  51.093 1.00 229.11 ? 277 ASP C C   1 
ATOM   9362  O O   . ASP C 1 269 ? -56.204 92.518  50.582 1.00 248.09 ? 277 ASP C O   1 
ATOM   9363  C CB  . ASP C 1 269 ? -55.438 90.522  48.818 1.00 190.99 ? 277 ASP C CB  1 
ATOM   9364  C CG  . ASP C 1 269 ? -53.972 90.888  48.693 1.00 164.40 ? 277 ASP C CG  1 
ATOM   9365  O OD1 . ASP C 1 269 ? -53.178 90.376  49.504 1.00 175.20 ? 277 ASP C OD1 1 
ATOM   9366  O OD2 . ASP C 1 269 ? -53.640 91.683  47.794 1.00 146.97 ? 277 ASP C OD2 1 
ATOM   9367  N N   . PRO C 1 270 ? -55.291 91.423  52.343 1.00 188.41 ? 278 PRO C N   1 
ATOM   9368  C CA  . PRO C 1 270 ? -55.148 92.635  53.129 1.00 160.81 ? 278 PRO C CA  1 
ATOM   9369  C C   . PRO C 1 270 ? -54.171 93.508  52.342 1.00 198.09 ? 278 PRO C C   1 
ATOM   9370  O O   . PRO C 1 270 ? -54.242 94.716  52.452 1.00 231.72 ? 278 PRO C O   1 
ATOM   9371  C CB  . PRO C 1 270 ? -54.494 92.162  54.427 1.00 30.00  ? 278 PRO C CB  1 
ATOM   9372  C CG  . PRO C 1 270 ? -54.803 90.681  54.486 1.00 30.00  ? 278 PRO C CG  1 
ATOM   9373  C CD  . PRO C 1 270 ? -54.824 90.227  53.042 1.00 30.00  ? 278 PRO C CD  1 
ATOM   9374  N N   . ALA C 1 271 ? -53.304 92.868  51.555 1.00 233.33 ? 279 ALA C N   1 
ATOM   9375  C CA  . ALA C 1 271 ? -52.284 93.620  50.784 1.00 208.17 ? 279 ALA C CA  1 
ATOM   9376  C C   . ALA C 1 271 ? -52.982 94.655  49.899 1.00 196.98 ? 279 ALA C C   1 
ATOM   9377  O O   . ALA C 1 271 ? -52.521 95.810  49.878 1.00 221.14 ? 279 ALA C O   1 
ATOM   9378  C CB  . ALA C 1 271 ? -51.429 92.678  49.950 1.00 30.00  ? 279 ALA C CB  1 
ATOM   9379  N N   . THR C 1 272 ? -54.048 94.261  49.201 1.00 172.19 ? 280 THR C N   1 
ATOM   9380  C CA  . THR C 1 272 ? -54.704 95.203  48.260 1.00 155.09 ? 280 THR C CA  1 
ATOM   9381  C C   . THR C 1 272 ? -56.132 95.478  48.726 1.00 159.18 ? 280 THR C C   1 
ATOM   9382  O O   . THR C 1 272 ? -56.777 96.370  48.149 1.00 140.42 ? 280 THR C O   1 
ATOM   9383  C CB  . THR C 1 272 ? -54.675 94.642  46.836 1.00 144.25 ? 280 THR C CB  1 
ATOM   9384  O OG1 . THR C 1 272 ? -55.349 93.384  46.858 1.00 182.18 ? 280 THR C OG1 1 
ATOM   9385  C CG2 . THR C 1 272 ? -53.271 94.458  46.306 1.00 90.93  ? 280 THR C CG2 1 
ATOM   9386  N N   . GLY C 1 273 ? -56.599 94.739  49.731 1.00 154.18 ? 281 GLY C N   1 
ATOM   9387  C CA  . GLY C 1 273 ? -57.988 94.894  50.197 1.00 124.99 ? 281 GLY C CA  1 
ATOM   9388  C C   . GLY C 1 273 ? -58.943 94.132  49.300 1.00 147.20 ? 281 GLY C C   1 
ATOM   9389  O O   . GLY C 1 273 ? -60.146 94.096  49.614 1.00 133.93 ? 281 GLY C O   1 
ATOM   9390  N N   . LYS C 1 274 ? -58.425 93.547  48.219 1.00 153.90 ? 282 LYS C N   1 
ATOM   9391  C CA  . LYS C 1 274 ? -59.280 92.791  47.269 1.00 129.81 ? 282 LYS C CA  1 
ATOM   9392  C C   . LYS C 1 274 ? -59.443 91.366  47.800 1.00 145.96 ? 282 LYS C C   1 
ATOM   9393  O O   . LYS C 1 274 ? -58.810 91.050  48.820 1.00 168.14 ? 282 LYS C O   1 
ATOM   9394  C CB  . LYS C 1 274 ? -58.680 92.829  45.861 1.00 84.28  ? 282 LYS C CB  1 
ATOM   9395  C CG  . LYS C 1 274 ? -59.576 92.285  44.759 1.00 72.79  ? 282 LYS C CG  1 
ATOM   9396  C CD  . LYS C 1 274 ? -60.917 92.974  44.696 1.00 70.85  ? 282 LYS C CD  1 
ATOM   9397  C CE  . LYS C 1 274 ? -61.840 92.355  43.670 1.00 85.87  ? 282 LYS C CE  1 
ATOM   9398  N NZ  . LYS C 1 274 ? -61.201 92.295  42.335 1.00 89.87  ? 282 LYS C NZ  1 
ATOM   9399  N N   . GLU C 1 275 ? -60.256 90.544  47.136 1.00 126.95 ? 283 GLU C N   1 
ATOM   9400  C CA  . GLU C 1 275 ? -60.538 89.180  47.646 1.00 133.42 ? 283 GLU C CA  1 
ATOM   9401  C C   . GLU C 1 275 ? -59.805 88.139  46.805 1.00 100.54 ? 283 GLU C C   1 
ATOM   9402  O O   . GLU C 1 275 ? -59.835 88.251  45.569 1.00 114.52 ? 283 GLU C O   1 
ATOM   9403  C CB  . GLU C 1 275 ? -62.043 88.925  47.617 1.00 141.21 ? 283 GLU C CB  1 
ATOM   9404  C CG  . GLU C 1 275 ? -62.640 88.952  46.225 1.00 137.52 ? 283 GLU C CG  1 
ATOM   9405  C CD  . GLU C 1 275 ? -64.122 88.622  46.181 1.00 167.34 ? 283 GLU C CD  1 
ATOM   9406  O OE1 . GLU C 1 275 ? -64.730 88.500  47.263 1.00 135.85 ? 283 GLU C OE1 1 
ATOM   9407  O OE2 . GLU C 1 275 ? -64.663 88.485  45.066 1.00 170.57 ? 283 GLU C OE2 1 
ATOM   9408  N N   . ILE C 1 276 ? -59.166 87.171  47.463 1.00 117.78 ? 284 ILE C N   1 
ATOM   9409  C CA  . ILE C 1 276 ? -58.485 86.066  46.732 1.00 116.09 ? 284 ILE C CA  1 
ATOM   9410  C C   . ILE C 1 276 ? -59.441 84.880  46.755 1.00 115.55 ? 284 ILE C C   1 
ATOM   9411  O O   . ILE C 1 276 ? -60.153 84.730  47.759 1.00 88.18  ? 284 ILE C O   1 
ATOM   9412  C CB  . ILE C 1 276 ? -57.122 85.746  47.366 1.00 108.12 ? 284 ILE C CB  1 
ATOM   9413  C CG1 . ILE C 1 276 ? -56.354 87.023  47.713 1.00 120.12 ? 284 ILE C CG1 1 
ATOM   9414  C CG2 . ILE C 1 276 ? -56.313 84.829  46.465 1.00 77.32  ? 284 ILE C CG2 1 
ATOM   9415  C CD1 . ILE C 1 276 ? -55.021 86.775  48.375 1.00 103.72 ? 284 ILE C CD1 1 
ATOM   9416  N N   . LEU C 1 277 ? -59.442 84.061  45.707 1.00 109.57 ? 285 LEU C N   1 
ATOM   9417  C CA  . LEU C 1 277 ? -60.477 83.002  45.624 1.00 110.97 ? 285 LEU C CA  1 
ATOM   9418  C C   . LEU C 1 277 ? -59.884 81.602  45.488 1.00 115.83 ? 285 LEU C C   1 
ATOM   9419  O O   . LEU C 1 277 ? -58.907 81.442  44.736 1.00 122.19 ? 285 LEU C O   1 
ATOM   9420  C CB  . LEU C 1 277 ? -61.343 83.324  44.403 1.00 100.21 ? 285 LEU C CB  1 
ATOM   9421  C CG  . LEU C 1 277 ? -61.813 84.771  44.289 1.00 89.47  ? 285 LEU C CG  1 
ATOM   9422  C CD1 . LEU C 1 277 ? -62.250 85.086  42.869 1.00 61.91  ? 285 LEU C CD1 1 
ATOM   9423  C CD2 . LEU C 1 277 ? -62.937 85.055  45.271 1.00 70.39  ? 285 LEU C CD2 1 
ATOM   9424  N N   . TYR C 1 278 ? -60.464 80.629  46.189 1.00 105.71 ? 286 TYR C N   1 
ATOM   9425  C CA  . TYR C 1 278 ? -60.065 79.239  46.044 1.00 96.02  ? 286 TYR C CA  1 
ATOM   9426  C C   . TYR C 1 278 ? -60.258 78.789  44.605 1.00 105.32 ? 286 TYR C C   1 
ATOM   9427  O O   . TYR C 1 278 ? -61.364 78.825  44.092 1.00 121.77 ? 286 TYR C O   1 
ATOM   9428  C CB  . TYR C 1 278 ? -60.908 78.278  46.897 1.00 93.42  ? 286 TYR C CB  1 
ATOM   9429  C CG  . TYR C 1 278 ? -60.423 78.262  48.339 1.00 106.69 ? 286 TYR C CG  1 
ATOM   9430  C CD1 . TYR C 1 278 ? -59.118 77.852  48.651 1.00 70.95  ? 286 TYR C CD1 1 
ATOM   9431  C CD2 . TYR C 1 278 ? -61.246 78.735  49.369 1.00 122.03 ? 286 TYR C CD2 1 
ATOM   9432  C CE1 . TYR C 1 278 ? -58.674 77.843  49.967 1.00 64.54  ? 286 TYR C CE1 1 
ATOM   9433  C CE2 . TYR C 1 278 ? -60.797 78.752  50.680 1.00 101.89 ? 286 TYR C CE2 1 
ATOM   9434  C CZ  . TYR C 1 278 ? -59.504 78.326  50.970 1.00 75.24  ? 286 TYR C CZ  1 
ATOM   9435  O OH  . TYR C 1 278 ? -59.067 78.335  52.261 1.00 64.64  ? 286 TYR C OH  1 
ATOM   9436  N N   . ASN C 1 279 ? -59.183 78.253  44.020 1.00 133.10 ? 287 ASN C N   1 
ATOM   9437  C CA  . ASN C 1 279 ? -59.196 77.673  42.695 1.00 115.82 ? 287 ASN C CA  1 
ATOM   9438  C C   . ASN C 1 279 ? -59.079 76.154  42.815 1.00 115.95 ? 287 ASN C C   1 
ATOM   9439  O O   . ASN C 1 279 ? -58.782 75.491  41.834 1.00 128.24 ? 287 ASN C O   1 
ATOM   9440  C CB  . ASN C 1 279 ? -58.077 78.308  41.880 1.00 127.61 ? 287 ASN C CB  1 
ATOM   9441  C CG  . ASN C 1 279 ? -58.205 77.992  40.412 1.00 152.88 ? 287 ASN C CG  1 
ATOM   9442  O OD1 . ASN C 1 279 ? -59.096 77.233  40.009 1.00 186.69 ? 287 ASN C OD1 1 
ATOM   9443  N ND2 . ASN C 1 279 ? -57.323 78.540  39.593 1.00 153.44 ? 287 ASN C ND2 1 
ATOM   9444  N N   . LEU C 1 280 ? -59.356 75.575  43.994 1.00 102.83 ? 288 LEU C N   1 
ATOM   9445  C CA  . LEU C 1 280 ? -59.235 74.149  44.248 1.00 100.91 ? 288 LEU C CA  1 
ATOM   9446  C C   . LEU C 1 280 ? -60.066 73.338  43.260 1.00 96.73  ? 288 LEU C C   1 
ATOM   9447  O O   . LEU C 1 280 ? -59.638 72.275  42.809 1.00 107.30 ? 288 LEU C O   1 
ATOM   9448  C CB  . LEU C 1 280 ? -59.644 73.798  45.681 1.00 90.61  ? 288 LEU C CB  1 
ATOM   9449  C CG  . LEU C 1 280 ? -58.729 74.356  46.770 1.00 91.33  ? 288 LEU C CG  1 
ATOM   9450  C CD1 . LEU C 1 280 ? -59.241 74.182  48.186 1.00 111.78 ? 288 LEU C CD1 1 
ATOM   9451  C CD2 . LEU C 1 280 ? -57.459 73.615  46.644 1.00 68.33  ? 288 LEU C CD2 1 
ATOM   9452  N N   . GLU C 1 281 ? -61.257 73.852  42.947 1.00 70.39  ? 289 GLU C N   1 
ATOM   9453  C CA  . GLU C 1 281 ? -62.176 73.169  42.067 1.00 69.05  ? 289 GLU C CA  1 
ATOM   9454  C C   . GLU C 1 281 ? -61.507 72.871  40.721 1.00 86.99  ? 289 GLU C C   1 
ATOM   9455  O O   . GLU C 1 281 ? -61.452 71.714  40.287 1.00 106.76 ? 289 GLU C O   1 
ATOM   9456  C CB  . GLU C 1 281 ? -63.496 73.919  41.947 1.00 66.87  ? 289 GLU C CB  1 
ATOM   9457  C CG  . GLU C 1 281 ? -64.475 73.203  41.029 1.00 87.55  ? 289 GLU C CG  1 
ATOM   9458  C CD  . GLU C 1 281 ? -65.900 73.717  41.164 1.00 112.51 ? 289 GLU C CD  1 
ATOM   9459  O OE1 . GLU C 1 281 ? -66.088 74.974  41.098 1.00 92.18  ? 289 GLU C OE1 1 
ATOM   9460  O OE2 . GLU C 1 281 ? -66.819 72.863  41.334 1.00 128.60 ? 289 GLU C OE2 1 
ATOM   9461  N N   . SER C 1 282 ? -61.002 73.887  40.024 1.00 81.33  ? 290 SER C N   1 
ATOM   9462  C CA  . SER C 1 282 ? -60.511 73.487  38.712 1.00 84.63  ? 290 SER C CA  1 
ATOM   9463  C C   . SER C 1 282 ? -59.230 72.658  38.828 1.00 82.71  ? 290 SER C C   1 
ATOM   9464  O O   . SER C 1 282 ? -59.108 71.663  38.127 1.00 89.28  ? 290 SER C O   1 
ATOM   9465  C CB  . SER C 1 282 ? -60.516 74.525  37.583 1.00 73.77  ? 290 SER C CB  1 
ATOM   9466  O OG  . SER C 1 282 ? -59.166 74.904  37.365 1.00 83.01  ? 290 SER C OG  1 
ATOM   9467  N N   . LEU C 1 283 ? -58.330 72.963  39.772 1.00 69.27  ? 291 LEU C N   1 
ATOM   9468  C CA  . LEU C 1 283 ? -57.116 72.167  39.923 1.00 78.34  ? 291 LEU C CA  1 
ATOM   9469  C C   . LEU C 1 283 ? -57.457 70.684  40.083 1.00 75.95  ? 291 LEU C C   1 
ATOM   9470  O O   . LEU C 1 283 ? -56.985 69.843  39.315 1.00 75.34  ? 291 LEU C O   1 
ATOM   9471  C CB  . LEU C 1 283 ? -56.281 72.667  41.101 1.00 89.03  ? 291 LEU C CB  1 
ATOM   9472  C CG  . LEU C 1 283 ? -55.691 74.067  40.906 1.00 75.69  ? 291 LEU C CG  1 
ATOM   9473  C CD1 . LEU C 1 283 ? -55.053 74.618  42.128 1.00 52.92  ? 291 LEU C CD1 1 
ATOM   9474  C CD2 . LEU C 1 283 ? -54.647 74.061  39.797 1.00 85.58  ? 291 LEU C CD2 1 
ATOM   9475  N N   . ILE C 1 284 ? -58.264 70.369  41.103 1.00 51.92  ? 292 ILE C N   1 
ATOM   9476  C CA  . ILE C 1 284 ? -58.607 68.987  41.386 1.00 49.69  ? 292 ILE C CA  1 
ATOM   9477  C C   . ILE C 1 284 ? -59.352 68.360  40.207 1.00 62.48  ? 292 ILE C C   1 
ATOM   9478  O O   . ILE C 1 284 ? -59.019 67.259  39.757 1.00 71.77  ? 292 ILE C O   1 
ATOM   9479  C CB  . ILE C 1 284 ? -59.427 68.933  42.680 1.00 44.97  ? 292 ILE C CB  1 
ATOM   9480  C CG1 . ILE C 1 284 ? -58.519 69.289  43.867 1.00 65.43  ? 292 ILE C CG1 1 
ATOM   9481  C CG2 . ILE C 1 284 ? -60.063 67.561  42.828 1.00 37.59  ? 292 ILE C CG2 1 
ATOM   9482  C CD1 . ILE C 1 284 ? -59.253 69.746  45.117 1.00 65.66  ? 292 ILE C CD1 1 
ATOM   9483  N N   . ASN C 1 285 ? -60.356 69.078  39.698 1.00 60.83  ? 293 ASN C N   1 
ATOM   9484  C CA  . ASN C 1 285 ? -61.095 68.606  38.548 1.00 65.09  ? 293 ASN C CA  1 
ATOM   9485  C C   . ASN C 1 285 ? -60.132 68.287  37.401 1.00 73.77  ? 293 ASN C C   1 
ATOM   9486  O O   . ASN C 1 285 ? -60.259 67.236  36.760 1.00 60.86  ? 293 ASN C O   1 
ATOM   9487  C CB  . ASN C 1 285 ? -62.255 69.516  38.188 1.00 60.64  ? 293 ASN C CB  1 
ATOM   9488  C CG  . ASN C 1 285 ? -63.392 69.334  39.157 1.00 78.93  ? 293 ASN C CG  1 
ATOM   9489  O OD1 . ASN C 1 285 ? -63.720 68.174  39.474 1.00 81.13  ? 293 ASN C OD1 1 
ATOM   9490  N ND2 . ASN C 1 285 ? -64.006 70.447  39.571 1.00 72.71  ? 293 ASN C ND2 1 
ATOM   9491  N N   . SER C 1 286 ? -59.149 69.176  37.156 1.00 54.71  ? 294 SER C N   1 
ATOM   9492  C CA  . SER C 1 286 ? -58.260 68.956  36.028 1.00 72.37  ? 294 SER C CA  1 
ATOM   9493  C C   . SER C 1 286 ? -57.354 67.759  36.290 1.00 81.41  ? 294 SER C C   1 
ATOM   9494  O O   . SER C 1 286 ? -56.978 67.039  35.370 1.00 93.90  ? 294 SER C O   1 
ATOM   9495  C CB  . SER C 1 286 ? -57.510 70.162  35.629 1.00 69.09  ? 294 SER C CB  1 
ATOM   9496  O OG  . SER C 1 286 ? -58.469 71.162  35.302 1.00 96.89  ? 294 SER C OG  1 
ATOM   9497  N N   . ALA C 1 287 ? -57.042 67.540  37.561 1.00 72.39  ? 295 ALA C N   1 
ATOM   9498  C CA  . ALA C 1 287 ? -56.182 66.437  37.953 1.00 89.16  ? 295 ALA C CA  1 
ATOM   9499  C C   . ALA C 1 287 ? -56.874 65.117  37.628 1.00 86.86  ? 295 ALA C C   1 
ATOM   9500  O O   . ALA C 1 287 ? -56.292 64.252  36.965 1.00 61.78  ? 295 ALA C O   1 
ATOM   9501  C CB  . ALA C 1 287 ? -55.857 66.550  39.422 1.00 110.80 ? 295 ALA C CB  1 
ATOM   9502  N N   . VAL C 1 288 ? -58.140 65.010  38.047 1.00 76.64  ? 296 VAL C N   1 
ATOM   9503  C CA  . VAL C 1 288 ? -58.895 63.811  37.768 1.00 70.96  ? 296 VAL C CA  1 
ATOM   9504  C C   . VAL C 1 288 ? -59.040 63.618  36.268 1.00 71.97  ? 296 VAL C C   1 
ATOM   9505  O O   . VAL C 1 288 ? -58.844 62.506  35.788 1.00 74.72  ? 296 VAL C O   1 
ATOM   9506  C CB  . VAL C 1 288 ? -60.264 63.848  38.445 1.00 66.49  ? 296 VAL C CB  1 
ATOM   9507  C CG1 . VAL C 1 288 ? -61.124 62.677  37.951 1.00 58.90  ? 296 VAL C CG1 1 
ATOM   9508  C CG2 . VAL C 1 288 ? -60.074 63.887  39.960 1.00 61.45  ? 296 VAL C CG2 1 
ATOM   9509  N N   . PHE C 1 289 ? -59.343 64.711  35.555 1.00 69.09  ? 297 PHE C N   1 
ATOM   9510  C CA  . PHE C 1 289 ? -59.475 64.613  34.102 1.00 73.81  ? 297 PHE C CA  1 
ATOM   9511  C C   . PHE C 1 289 ? -59.196 65.977  33.478 1.00 73.24  ? 297 PHE C C   1 
ATOM   9512  O O   . PHE C 1 289 ? -59.822 66.961  33.899 1.00 64.91  ? 297 PHE C O   1 
ATOM   9513  C CB  . PHE C 1 289 ? -60.832 64.093  33.588 1.00 53.79  ? 297 PHE C CB  1 
ATOM   9514  C CG  . PHE C 1 289 ? -60.758 63.836  32.097 1.00 53.54  ? 297 PHE C CG  1 
ATOM   9515  C CD1 . PHE C 1 289 ? -60.327 62.620  31.590 1.00 79.19  ? 297 PHE C CD1 1 
ATOM   9516  C CD2 . PHE C 1 289 ? -61.060 64.829  31.183 1.00 53.73  ? 297 PHE C CD2 1 
ATOM   9517  C CE1 . PHE C 1 289 ? -60.248 62.409  30.206 1.00 70.33  ? 297 PHE C CE1 1 
ATOM   9518  C CE2 . PHE C 1 289 ? -61.041 64.599  29.813 1.00 45.83  ? 297 PHE C CE2 1 
ATOM   9519  C CZ  . PHE C 1 289 ? -60.599 63.400  29.321 1.00 49.27  ? 297 PHE C CZ  1 
ATOM   9520  N N   . PRO C 1 290 ? -58.318 66.107  32.447 1.00 76.55  ? 298 PRO C N   1 
ATOM   9521  C CA  . PRO C 1 290 ? -57.632 65.004  31.748 1.00 86.90  ? 298 PRO C CA  1 
ATOM   9522  C C   . PRO C 1 290 ? -56.267 64.582  32.309 1.00 88.77  ? 298 PRO C C   1 
ATOM   9523  O O   . PRO C 1 290 ? -55.283 64.255  31.617 1.00 86.70  ? 298 PRO C O   1 
ATOM   9524  C CB  . PRO C 1 290 ? -57.478 65.774  30.415 1.00 67.86  ? 298 PRO C CB  1 
ATOM   9525  C CG  . PRO C 1 290 ? -56.858 67.091  30.882 1.00 42.38  ? 298 PRO C CG  1 
ATOM   9526  C CD  . PRO C 1 290 ? -57.924 67.417  31.911 1.00 56.63  ? 298 PRO C CD  1 
ATOM   9527  N N   . GLY C 1 291 ? -56.170 64.624  33.615 1.00 63.16  ? 299 GLY C N   1 
ATOM   9528  C CA  . GLY C 1 291 ? -54.838 64.444  34.148 1.00 70.17  ? 299 GLY C CA  1 
ATOM   9529  C C   . GLY C 1 291 ? -54.547 62.975  34.360 1.00 78.28  ? 299 GLY C C   1 
ATOM   9530  O O   . GLY C 1 291 ? -53.576 62.472  33.811 1.00 82.79  ? 299 GLY C O   1 
ATOM   9531  N N   . LEU C 1 292 ? -55.382 62.320  35.181 1.00 80.88  ? 300 LEU C N   1 
ATOM   9532  C CA  . LEU C 1 292 ? -55.063 60.985  35.671 1.00 67.00  ? 300 LEU C CA  1 
ATOM   9533  C C   . LEU C 1 292 ? -56.029 59.952  35.104 1.00 82.75  ? 300 LEU C C   1 
ATOM   9534  O O   . LEU C 1 292 ? -55.638 58.818  34.842 1.00 100.69 ? 300 LEU C O   1 
ATOM   9535  C CB  . LEU C 1 292 ? -55.050 60.950  37.202 1.00 56.81  ? 300 LEU C CB  1 
ATOM   9536  C CG  . LEU C 1 292 ? -54.009 61.879  37.863 1.00 63.47  ? 300 LEU C CG  1 
ATOM   9537  C CD1 . LEU C 1 292 ? -54.221 62.427  39.264 1.00 49.82  ? 300 LEU C CD1 1 
ATOM   9538  C CD2 . LEU C 1 292 ? -52.571 61.497  37.701 1.00 54.95  ? 300 LEU C CD2 1 
ATOM   9539  N N   . GLN C 1 293 ? -57.313 60.300  34.963 1.00 86.32  ? 301 GLN C N   1 
ATOM   9540  C CA  . GLN C 1 293 ? -58.316 59.275  34.682 1.00 70.12  ? 301 GLN C CA  1 
ATOM   9541  C C   . GLN C 1 293 ? -58.734 59.361  33.212 1.00 64.30  ? 301 GLN C C   1 
ATOM   9542  O O   . GLN C 1 293 ? -58.342 60.277  32.509 1.00 66.11  ? 301 GLN C O   1 
ATOM   9543  C CB  . GLN C 1 293 ? -59.478 59.365  35.674 1.00 65.44  ? 301 GLN C CB  1 
ATOM   9544  C CG  . GLN C 1 293 ? -59.023 59.155  37.116 1.00 65.76  ? 301 GLN C CG  1 
ATOM   9545  C CD  . GLN C 1 293 ? -60.143 58.806  38.065 1.00 66.18  ? 301 GLN C CD  1 
ATOM   9546  O OE1 . GLN C 1 293 ? -59.914 58.210  39.119 1.00 60.40  ? 301 GLN C OE1 1 
ATOM   9547  N NE2 . GLN C 1 293 ? -61.352 59.157  37.652 1.00 80.97  ? 301 GLN C NE2 1 
ATOM   9548  N N   . GLY C 1 294 ? -59.494 58.369  32.734 1.00 61.04  ? 302 GLY C N   1 
ATOM   9549  C CA  . GLY C 1 294 ? -60.204 58.506  31.482 1.00 54.46  ? 302 GLY C CA  1 
ATOM   9550  C C   . GLY C 1 294 ? -61.699 58.490  31.756 1.00 78.53  ? 302 GLY C C   1 
ATOM   9551  O O   . GLY C 1 294 ? -62.194 59.283  32.566 1.00 129.19 ? 302 GLY C O   1 
ATOM   9552  N N   . GLY C 1 295 ? -62.395 57.558  31.099 1.00 86.23  ? 303 GLY C N   1 
ATOM   9553  C CA  . GLY C 1 295 ? -63.841 57.454  31.222 1.00 88.04  ? 303 GLY C CA  1 
ATOM   9554  C C   . GLY C 1 295 ? -64.284 57.257  32.664 1.00 71.62  ? 303 GLY C C   1 
ATOM   9555  O O   . GLY C 1 295 ? -63.848 56.330  33.320 1.00 97.94  ? 303 GLY C O   1 
ATOM   9556  N N   . PRO C 1 296 ? -65.187 58.096  33.186 1.00 66.43  ? 304 PRO C N   1 
ATOM   9557  C CA  . PRO C 1 296 ? -65.772 57.888  34.509 1.00 77.75  ? 304 PRO C CA  1 
ATOM   9558  C C   . PRO C 1 296 ? -66.508 56.554  34.568 1.00 76.08  ? 304 PRO C C   1 
ATOM   9559  O O   . PRO C 1 296 ? -67.053 56.127  33.537 1.00 74.01  ? 304 PRO C O   1 
ATOM   9560  C CB  . PRO C 1 296 ? -66.751 59.080  34.565 1.00 84.00  ? 304 PRO C CB  1 
ATOM   9561  C CG  . PRO C 1 296 ? -66.066 60.135  33.737 1.00 93.98  ? 304 PRO C CG  1 
ATOM   9562  C CD  . PRO C 1 296 ? -65.698 59.301  32.538 1.00 99.18  ? 304 PRO C CD  1 
ATOM   9563  N N   . HIS C 1 297 ? -66.515 55.914  35.770 1.00 64.81  ? 305 HIS C N   1 
ATOM   9564  C CA  . HIS C 1 297 ? -67.219 54.630  35.907 1.00 91.89  ? 305 HIS C CA  1 
ATOM   9565  C C   . HIS C 1 297 ? -68.669 54.844  36.320 1.00 98.02  ? 305 HIS C C   1 
ATOM   9566  O O   . HIS C 1 297 ? -68.967 54.761  37.517 1.00 73.26  ? 305 HIS C O   1 
ATOM   9567  C CB  . HIS C 1 297 ? -66.512 53.617  36.825 1.00 64.31  ? 305 HIS C CB  1 
ATOM   9568  C CG  . HIS C 1 297 ? -65.241 53.173  36.195 1.00 80.49  ? 305 HIS C CG  1 
ATOM   9569  N ND1 . HIS C 1 297 ? -64.254 52.471  36.820 1.00 80.06  ? 305 HIS C ND1 1 
ATOM   9570  C CD2 . HIS C 1 297 ? -64.787 53.348  34.939 1.00 100.65 ? 305 HIS C CD2 1 
ATOM   9571  C CE1 . HIS C 1 297 ? -63.236 52.270  35.982 1.00 75.41  ? 305 HIS C CE1 1 
ATOM   9572  N NE2 . HIS C 1 297 ? -63.543 52.786  34.836 1.00 101.68 ? 305 HIS C NE2 1 
ATOM   9573  N N   . ASN C 1 298 ? -69.561 55.080  35.342 1.00 94.17  ? 306 ASN C N   1 
ATOM   9574  C CA  . ASN C 1 298 ? -70.844 55.663  35.727 1.00 98.48  ? 306 ASN C CA  1 
ATOM   9575  C C   . ASN C 1 298 ? -71.651 54.728  36.623 1.00 114.50 ? 306 ASN C C   1 
ATOM   9576  O O   . ASN C 1 298 ? -72.383 55.154  37.525 1.00 109.40 ? 306 ASN C O   1 
ATOM   9577  C CB  . ASN C 1 298 ? -71.629 56.187  34.536 1.00 76.01  ? 306 ASN C CB  1 
ATOM   9578  C CG  . ASN C 1 298 ? -70.907 57.324  33.840 1.00 102.52 ? 306 ASN C CG  1 
ATOM   9579  O OD1 . ASN C 1 298 ? -70.795 58.444  34.385 1.00 76.76  ? 306 ASN C OD1 1 
ATOM   9580  N ND2 . ASN C 1 298 ? -70.425 57.053  32.625 1.00 140.04 ? 306 ASN C ND2 1 
ATOM   9581  N N   . HIS C 1 299 ? -71.527 53.434  36.336 1.00 105.85 ? 307 HIS C N   1 
ATOM   9582  C CA  . HIS C 1 299 ? -72.216 52.411  37.105 1.00 96.84  ? 307 HIS C CA  1 
ATOM   9583  C C   . HIS C 1 299 ? -71.767 52.443  38.566 1.00 99.96  ? 307 HIS C C   1 
ATOM   9584  O O   . HIS C 1 299 ? -72.567 52.182  39.471 1.00 81.04  ? 307 HIS C O   1 
ATOM   9585  C CB  . HIS C 1 299 ? -71.942 51.055  36.469 1.00 106.21 ? 307 HIS C CB  1 
ATOM   9586  C CG  . HIS C 1 299 ? -70.496 50.723  36.356 1.00 102.72 ? 307 HIS C CG  1 
ATOM   9587  N ND1 . HIS C 1 299 ? -69.597 51.309  35.488 1.00 107.18 ? 307 HIS C ND1 1 
ATOM   9588  C CD2 . HIS C 1 299 ? -69.808 49.861  37.071 1.00 108.74 ? 307 HIS C CD2 1 
ATOM   9589  C CE1 . HIS C 1 299 ? -68.398 50.785  35.673 1.00 105.88 ? 307 HIS C CE1 1 
ATOM   9590  N NE2 . HIS C 1 299 ? -68.515 49.884  36.611 1.00 120.83 ? 307 HIS C NE2 1 
ATOM   9591  N N   . ALA C 1 300 ? -70.486 52.789  38.798 1.00 94.14  ? 308 ALA C N   1 
ATOM   9592  C CA  . ALA C 1 300 ? -70.006 52.957  40.169 1.00 71.89  ? 308 ALA C CA  1 
ATOM   9593  C C   . ALA C 1 300 ? -70.556 54.229  40.797 1.00 68.40  ? 308 ALA C C   1 
ATOM   9594  O O   . ALA C 1 300 ? -70.914 54.203  41.979 1.00 54.05  ? 308 ALA C O   1 
ATOM   9595  C CB  . ALA C 1 300 ? -68.514 52.943  40.245 1.00 66.49  ? 308 ALA C CB  1 
ATOM   9596  N N   . ILE C 1 301 ? -70.666 55.300  39.979 1.00 72.49  ? 309 ILE C N   1 
ATOM   9597  C CA  . ILE C 1 301 ? -71.148 56.571  40.498 1.00 87.11  ? 309 ILE C CA  1 
ATOM   9598  C C   . ILE C 1 301 ? -72.600 56.407  40.948 1.00 99.07  ? 309 ILE C C   1 
ATOM   9599  O O   . ILE C 1 301 ? -72.994 56.933  42.009 1.00 85.84  ? 309 ILE C O   1 
ATOM   9600  C CB  . ILE C 1 301 ? -70.964 57.711  39.486 1.00 65.81  ? 309 ILE C CB  1 
ATOM   9601  C CG1 . ILE C 1 301 ? -69.525 58.077  39.368 1.00 64.93  ? 309 ILE C CG1 1 
ATOM   9602  C CG2 . ILE C 1 301 ? -71.763 58.946  39.899 1.00 63.69  ? 309 ILE C CG2 1 
ATOM   9603  C CD1 . ILE C 1 301 ? -69.254 58.897  38.120 1.00 78.57  ? 309 ILE C CD1 1 
ATOM   9604  N N   . ALA C 1 302 ? -73.350 55.623  40.155 1.00 84.55  ? 310 ALA C N   1 
ATOM   9605  C CA  . ALA C 1 302 ? -74.734 55.324  40.498 1.00 91.60  ? 310 ALA C CA  1 
ATOM   9606  C C   . ALA C 1 302 ? -74.801 54.660  41.886 1.00 94.78  ? 310 ALA C C   1 
ATOM   9607  O O   . ALA C 1 302 ? -75.592 55.046  42.767 1.00 84.40  ? 310 ALA C O   1 
ATOM   9608  C CB  . ALA C 1 302 ? -75.324 54.439  39.417 1.00 87.43  ? 310 ALA C CB  1 
ATOM   9609  N N   . GLY C 1 303 ? -73.961 53.626  42.059 1.00 97.57  ? 311 GLY C N   1 
ATOM   9610  C CA  . GLY C 1 303 ? -73.893 52.905  43.318 1.00 99.04  ? 311 GLY C CA  1 
ATOM   9611  C C   . GLY C 1 303 ? -73.593 53.839  44.488 1.00 88.44  ? 311 GLY C C   1 
ATOM   9612  O O   . GLY C 1 303 ? -74.183 53.711  45.560 1.00 65.19  ? 311 GLY C O   1 
ATOM   9613  N N   . VAL C 1 304 ? -72.685 54.788  44.249 1.00 85.19  ? 312 VAL C N   1 
ATOM   9614  C CA  . VAL C 1 304 ? -72.283 55.717  45.285 1.00 87.58  ? 312 VAL C CA  1 
ATOM   9615  C C   . VAL C 1 304 ? -73.465 56.612  45.636 1.00 100.25 ? 312 VAL C C   1 
ATOM   9616  O O   . VAL C 1 304 ? -73.717 56.885  46.819 1.00 74.90  ? 312 VAL C O   1 
ATOM   9617  C CB  . VAL C 1 304 ? -71.076 56.556  44.827 1.00 64.79  ? 312 VAL C CB  1 
ATOM   9618  C CG1 . VAL C 1 304 ? -70.736 57.696  45.841 1.00 50.57  ? 312 VAL C CG1 1 
ATOM   9619  C CG2 . VAL C 1 304 ? -69.911 55.615  44.494 1.00 47.99  ? 312 VAL C CG2 1 
ATOM   9620  N N   . ALA C 1 305 ? -74.163 57.063  44.589 1.00 112.26 ? 313 ALA C N   1 
ATOM   9621  C CA  . ALA C 1 305 ? -75.330 57.901  44.785 1.00 116.06 ? 313 ALA C CA  1 
ATOM   9622  C C   . ALA C 1 305 ? -76.277 57.188  45.753 1.00 106.49 ? 313 ALA C C   1 
ATOM   9623  O O   . ALA C 1 305 ? -76.610 57.726  46.814 1.00 91.32  ? 313 ALA C O   1 
ATOM   9624  C CB  . ALA C 1 305 ? -75.992 58.225  43.456 1.00 104.74 ? 313 ALA C CB  1 
ATOM   9625  N N   . VAL C 1 306 ? -76.622 55.937  45.412 1.00 104.80 ? 314 VAL C N   1 
ATOM   9626  C CA  . VAL C 1 306 ? -77.566 55.147  46.180 1.00 111.37 ? 314 VAL C CA  1 
ATOM   9627  C C   . VAL C 1 306 ? -77.111 55.064  47.636 1.00 113.60 ? 314 VAL C C   1 
ATOM   9628  O O   . VAL C 1 306 ? -77.920 55.241  48.554 1.00 118.59 ? 314 VAL C O   1 
ATOM   9629  C CB  . VAL C 1 306 ? -77.800 53.751  45.585 1.00 106.68 ? 314 VAL C CB  1 
ATOM   9630  C CG1 . VAL C 1 306 ? -78.497 52.873  46.616 1.00 81.92  ? 314 VAL C CG1 1 
ATOM   9631  C CG2 . VAL C 1 306 ? -78.582 53.836  44.263 1.00 81.84  ? 314 VAL C CG2 1 
ATOM   9632  N N   . ALA C 1 307 ? -75.804 54.830  47.812 1.00 102.55 ? 315 ALA C N   1 
ATOM   9633  C CA  . ALA C 1 307 ? -75.188 54.739  49.132 1.00 112.05 ? 315 ALA C CA  1 
ATOM   9634  C C   . ALA C 1 307 ? -75.387 56.015  49.943 1.00 89.95  ? 315 ALA C C   1 
ATOM   9635  O O   . ALA C 1 307 ? -75.703 55.943  51.152 1.00 69.17  ? 315 ALA C O   1 
ATOM   9636  C CB  . ALA C 1 307 ? -73.715 54.419  49.009 1.00 108.69 ? 315 ALA C CB  1 
ATOM   9637  N N   . LEU C 1 308 ? -75.149 57.153  49.259 1.00 73.63  ? 316 LEU C N   1 
ATOM   9638  C CA  . LEU C 1 308 ? -75.180 58.452  49.911 1.00 88.39  ? 316 LEU C CA  1 
ATOM   9639  C C   . LEU C 1 308 ? -76.602 58.720  50.392 1.00 100.53 ? 316 LEU C C   1 
ATOM   9640  O O   . LEU C 1 308 ? -76.811 59.275  51.482 1.00 86.39  ? 316 LEU C O   1 
ATOM   9641  C CB  . LEU C 1 308 ? -74.709 59.508  48.917 1.00 95.84  ? 316 LEU C CB  1 
ATOM   9642  C CG  . LEU C 1 308 ? -73.203 59.564  48.637 1.00 109.68 ? 316 LEU C CG  1 
ATOM   9643  C CD1 . LEU C 1 308 ? -72.917 60.457  47.461 1.00 108.13 ? 316 LEU C CD1 1 
ATOM   9644  C CD2 . LEU C 1 308 ? -72.493 60.099  49.843 1.00 104.64 ? 316 LEU C CD2 1 
ATOM   9645  N N   . LYS C 1 309 ? -77.577 58.330  49.554 1.00 102.48 ? 317 LYS C N   1 
ATOM   9646  C CA  . LYS C 1 309 ? -78.965 58.515  49.912 1.00 93.09  ? 317 LYS C CA  1 
ATOM   9647  C C   . LYS C 1 309 ? -79.243 57.728  51.179 1.00 94.32  ? 317 LYS C C   1 
ATOM   9648  O O   . LYS C 1 309 ? -79.949 58.218  52.052 1.00 117.07 ? 317 LYS C O   1 
ATOM   9649  C CB  . LYS C 1 309 ? -79.992 58.149  48.844 1.00 78.12  ? 317 LYS C CB  1 
ATOM   9650  C CG  . LYS C 1 309 ? -81.392 58.191  49.485 1.00 78.91  ? 317 LYS C CG  1 
ATOM   9651  C CD  . LYS C 1 309 ? -82.514 57.821  48.530 1.00 96.30  ? 317 LYS C CD  1 
ATOM   9652  C CE  . LYS C 1 309 ? -83.805 57.577  49.219 1.00 63.58  ? 317 LYS C CE  1 
ATOM   9653  N NZ  . LYS C 1 309 ? -84.554 56.632  48.379 1.00 60.83  ? 317 LYS C NZ  1 
ATOM   9654  N N   . GLN C 1 310 ? -78.745 56.494  51.252 1.00 105.51 ? 318 GLN C N   1 
ATOM   9655  C CA  . GLN C 1 310 ? -78.966 55.697  52.450 1.00 124.04 ? 318 GLN C CA  1 
ATOM   9656  C C   . GLN C 1 310 ? -78.271 56.314  53.649 1.00 115.01 ? 318 GLN C C   1 
ATOM   9657  O O   . GLN C 1 310 ? -78.785 56.205  54.754 1.00 103.34 ? 318 GLN C O   1 
ATOM   9658  C CB  . GLN C 1 310 ? -78.433 54.278  52.365 1.00 103.19 ? 318 GLN C CB  1 
ATOM   9659  C CG  . GLN C 1 310 ? -79.163 53.523  51.274 1.00 86.83  ? 318 GLN C CG  1 
ATOM   9660  C CD  . GLN C 1 310 ? -78.514 52.194  51.056 1.00 117.57 ? 318 GLN C CD  1 
ATOM   9661  O OE1 . GLN C 1 310 ? -79.057 51.415  50.271 1.00 147.73 ? 318 GLN C OE1 1 
ATOM   9662  N NE2 . GLN C 1 310 ? -77.392 51.945  51.746 1.00 137.59 ? 318 GLN C NE2 1 
ATOM   9663  N N   . ALA C 1 311 ? -77.116 56.947  53.407 1.00 99.49  ? 319 ALA C N   1 
ATOM   9664  C CA  . ALA C 1 311 ? -76.344 57.551  54.480 1.00 75.81  ? 319 ALA C CA  1 
ATOM   9665  C C   . ALA C 1 311 ? -77.138 58.659  55.177 1.00 83.60  ? 319 ALA C C   1 
ATOM   9666  O O   . ALA C 1 311 ? -76.841 59.006  56.308 1.00 68.30  ? 319 ALA C O   1 
ATOM   9667  C CB  . ALA C 1 311 ? -75.042 58.072  53.943 1.00 55.36  ? 319 ALA C CB  1 
ATOM   9668  N N   . MET C 1 312 ? -78.127 59.240  54.495 1.00 97.01  ? 320 MET C N   1 
ATOM   9669  C CA  . MET C 1 312 ? -78.874 60.358  55.043 1.00 91.66  ? 320 MET C CA  1 
ATOM   9670  C C   . MET C 1 312 ? -80.142 59.886  55.772 1.00 92.46  ? 320 MET C C   1 
ATOM   9671  O O   . MET C 1 312 ? -80.862 60.717  56.297 1.00 144.89 ? 320 MET C O   1 
ATOM   9672  C CB  . MET C 1 312 ? -79.231 61.328  53.911 1.00 78.00  ? 320 MET C CB  1 
ATOM   9673  C CG  . MET C 1 312 ? -78.088 62.176  53.444 1.00 105.86 ? 320 MET C CG  1 
ATOM   9674  S SD  . MET C 1 312 ? -78.341 63.297  52.035 1.00 109.51 ? 320 MET C SD  1 
ATOM   9675  C CE  . MET C 1 312 ? -78.761 62.199  50.671 1.00 93.15  ? 320 MET C CE  1 
ATOM   9676  N N   . THR C 1 313 ? -80.403 58.573  55.839 1.00 68.60  ? 321 THR C N   1 
ATOM   9677  C CA  . THR C 1 313 ? -81.521 58.012  56.578 1.00 74.20  ? 321 THR C CA  1 
ATOM   9678  C C   . THR C 1 313 ? -81.211 57.883  58.075 1.00 91.77  ? 321 THR C C   1 
ATOM   9679  O O   . THR C 1 313 ? -80.061 57.824  58.523 1.00 101.74 ? 321 THR C O   1 
ATOM   9680  C CB  . THR C 1 313 ? -81.860 56.637  55.998 1.00 99.08  ? 321 THR C CB  1 
ATOM   9681  O OG1 . THR C 1 313 ? -80.917 55.675  56.490 1.00 93.78  ? 321 THR C OG1 1 
ATOM   9682  C CG2 . THR C 1 313 ? -81.937 56.648  54.476 1.00 95.41  ? 321 THR C CG2 1 
ATOM   9683  N N   . LEU C 1 314 ? -82.279 57.812  58.873 1.00 98.01  ? 322 LEU C N   1 
ATOM   9684  C CA  . LEU C 1 314 ? -82.104 57.750  60.311 1.00 112.16 ? 322 LEU C CA  1 
ATOM   9685  C C   . LEU C 1 314 ? -81.570 56.372  60.671 1.00 125.48 ? 322 LEU C C   1 
ATOM   9686  O O   . LEU C 1 314 ? -80.795 56.259  61.608 1.00 132.77 ? 322 LEU C O   1 
ATOM   9687  C CB  . LEU C 1 314 ? -83.348 58.134  61.110 1.00 111.07 ? 322 LEU C CB  1 
ATOM   9688  C CG  . LEU C 1 314 ? -83.413 57.587  62.540 1.00 107.02 ? 322 LEU C CG  1 
ATOM   9689  C CD1 . LEU C 1 314 ? -82.579 58.341  63.565 1.00 80.08  ? 322 LEU C CD1 1 
ATOM   9690  C CD2 . LEU C 1 314 ? -84.836 57.445  62.971 1.00 113.65 ? 322 LEU C CD2 1 
ATOM   9691  N N   . GLU C 1 315 ? -81.960 55.354  59.891 1.00 108.93 ? 323 GLU C N   1 
ATOM   9692  C CA  . GLU C 1 315 ? -81.501 53.982  60.100 1.00 106.85 ? 323 GLU C CA  1 
ATOM   9693  C C   . GLU C 1 315 ? -79.977 53.923  60.028 1.00 97.44  ? 323 GLU C C   1 
ATOM   9694  O O   . GLU C 1 315 ? -79.369 53.230  60.849 1.00 103.38 ? 323 GLU C O   1 
ATOM   9695  C CB  . GLU C 1 315 ? -81.983 52.967  59.063 1.00 111.09 ? 323 GLU C CB  1 
ATOM   9696  C CG  . GLU C 1 315 ? -83.491 52.786  58.940 1.00 85.38  ? 323 GLU C CG  1 
ATOM   9697  C CD  . GLU C 1 315 ? -84.209 54.081  58.618 1.00 95.14  ? 323 GLU C CD  1 
ATOM   9698  O OE1 . GLU C 1 315 ? -83.624 55.189  58.597 1.00 92.16  ? 323 GLU C OE1 1 
ATOM   9699  O OE2 . GLU C 1 315 ? -85.408 53.967  58.389 1.00 112.96 ? 323 GLU C OE2 1 
ATOM   9700  N N   . PHE C 1 316 ? -79.406 54.630  59.027 1.00 66.32  ? 324 PHE C N   1 
ATOM   9701  C CA  . PHE C 1 316 ? -77.964 54.817  58.928 1.00 71.62  ? 324 PHE C CA  1 
ATOM   9702  C C   . PHE C 1 316 ? -77.400 55.441  60.220 1.00 81.11  ? 324 PHE C C   1 
ATOM   9703  O O   . PHE C 1 316 ? -76.445 54.886  60.769 1.00 76.57  ? 324 PHE C O   1 
ATOM   9704  C CB  . PHE C 1 316 ? -77.556 55.617  57.681 1.00 76.06  ? 324 PHE C CB  1 
ATOM   9705  C CG  . PHE C 1 316 ? -76.065 55.643  57.342 1.00 86.22  ? 324 PHE C CG  1 
ATOM   9706  C CD1 . PHE C 1 316 ? -75.492 54.617  56.607 1.00 104.31 ? 324 PHE C CD1 1 
ATOM   9707  C CD2 . PHE C 1 316 ? -75.224 56.689  57.744 1.00 97.68  ? 324 PHE C CD2 1 
ATOM   9708  C CE1 . PHE C 1 316 ? -74.144 54.665  56.275 1.00 126.04 ? 324 PHE C CE1 1 
ATOM   9709  C CE2 . PHE C 1 316 ? -73.869 56.725  57.426 1.00 76.72  ? 324 PHE C CE2 1 
ATOM   9710  C CZ  . PHE C 1 316 ? -73.326 55.705  56.712 1.00 90.60  ? 324 PHE C CZ  1 
ATOM   9711  N N   . LYS C 1 317 ? -77.960 56.591  60.677 1.00 66.56  ? 325 LYS C N   1 
ATOM   9712  C CA  . LYS C 1 317 ? -77.483 57.309  61.853 1.00 91.66  ? 325 LYS C CA  1 
ATOM   9713  C C   . LYS C 1 317 ? -77.420 56.358  63.066 1.00 97.32  ? 325 LYS C C   1 
ATOM   9714  O O   . LYS C 1 317 ? -76.429 56.329  63.836 1.00 75.95  ? 325 LYS C O   1 
ATOM   9715  C CB  . LYS C 1 317 ? -78.343 58.566  62.058 1.00 82.58  ? 325 LYS C CB  1 
ATOM   9716  C CG  . LYS C 1 317 ? -77.952 59.561  63.176 1.00 72.59  ? 325 LYS C CG  1 
ATOM   9717  C CD  . LYS C 1 317 ? -79.079 60.623  63.181 1.00 117.47 ? 325 LYS C CD  1 
ATOM   9718  C CE  . LYS C 1 317 ? -79.208 61.851  64.103 1.00 119.89 ? 325 LYS C CE  1 
ATOM   9719  N NZ  . LYS C 1 317 ? -80.515 62.174  64.721 1.00 67.01  ? 325 LYS C NZ  1 
ATOM   9720  N N   . VAL C 1 318 ? -78.466 55.533  63.185 1.00 78.36  ? 326 VAL C N   1 
ATOM   9721  C CA  . VAL C 1 318 ? -78.483 54.612  64.303 1.00 82.29  ? 326 VAL C CA  1 
ATOM   9722  C C   . VAL C 1 318 ? -77.412 53.530  64.126 1.00 98.23  ? 326 VAL C C   1 
ATOM   9723  O O   . VAL C 1 318 ? -76.637 53.283  65.068 1.00 77.84  ? 326 VAL C O   1 
ATOM   9724  C CB  . VAL C 1 318 ? -79.836 54.050  64.749 1.00 77.17  ? 326 VAL C CB  1 
ATOM   9725  C CG1 . VAL C 1 318 ? -79.747 53.677  66.221 1.00 74.74  ? 326 VAL C CG1 1 
ATOM   9726  C CG2 . VAL C 1 318 ? -80.965 55.046  64.616 1.00 62.94  ? 326 VAL C CG2 1 
ATOM   9727  N N   . TYR C 1 319 ? -77.330 52.961  62.908 1.00 98.39  ? 327 TYR C N   1 
ATOM   9728  C CA  . TYR C 1 319 ? -76.283 52.016  62.531 1.00 88.35  ? 327 TYR C CA  1 
ATOM   9729  C C   . TYR C 1 319 ? -74.906 52.521  62.988 1.00 105.39 ? 327 TYR C C   1 
ATOM   9730  O O   . TYR C 1 319 ? -74.167 51.805  63.664 1.00 114.17 ? 327 TYR C O   1 
ATOM   9731  C CB  . TYR C 1 319 ? -76.272 51.732  61.020 1.00 84.90  ? 327 TYR C CB  1 
ATOM   9732  C CG  . TYR C 1 319 ? -74.982 51.086  60.521 1.00 99.26  ? 327 TYR C CG  1 
ATOM   9733  C CD1 . TYR C 1 319 ? -74.654 49.782  60.875 1.00 112.28 ? 327 TYR C CD1 1 
ATOM   9734  C CD2 . TYR C 1 319 ? -74.082 51.762  59.708 1.00 94.67  ? 327 TYR C CD2 1 
ATOM   9735  C CE1 . TYR C 1 319 ? -73.479 49.180  60.454 1.00 98.93  ? 327 TYR C CE1 1 
ATOM   9736  C CE2 . TYR C 1 319 ? -72.914 51.159  59.264 1.00 85.82  ? 327 TYR C CE2 1 
ATOM   9737  C CZ  . TYR C 1 319 ? -72.594 49.874  59.646 1.00 88.29  ? 327 TYR C CZ  1 
ATOM   9738  O OH  . TYR C 1 319 ? -71.423 49.320  59.203 1.00 68.77  ? 327 TYR C OH  1 
ATOM   9739  N N   . GLN C 1 320 ? -74.547 53.760  62.621 1.00 94.07  ? 328 GLN C N   1 
ATOM   9740  C CA  . GLN C 1 320 ? -73.259 54.314  63.000 1.00 89.07  ? 328 GLN C CA  1 
ATOM   9741  C C   . GLN C 1 320 ? -73.122 54.387  64.522 1.00 94.61  ? 328 GLN C C   1 
ATOM   9742  O O   . GLN C 1 320 ? -72.056 54.068  65.076 1.00 88.12  ? 328 GLN C O   1 
ATOM   9743  C CB  . GLN C 1 320 ? -72.965 55.626  62.276 1.00 79.53  ? 328 GLN C CB  1 
ATOM   9744  C CG  . GLN C 1 320 ? -72.799 55.449  60.765 1.00 102.47 ? 328 GLN C CG  1 
ATOM   9745  C CD  . GLN C 1 320 ? -71.656 54.549  60.326 1.00 109.86 ? 328 GLN C CD  1 
ATOM   9746  O OE1 . GLN C 1 320 ? -70.776 54.178  61.096 1.00 138.20 ? 328 GLN C OE1 1 
ATOM   9747  N NE2 . GLN C 1 320 ? -71.632 54.179  59.064 1.00 113.65 ? 328 GLN C NE2 1 
ATOM   9748  N N   . HIS C 1 321 ? -74.189 54.829  65.210 1.00 99.66  ? 329 HIS C N   1 
ATOM   9749  C CA  . HIS C 1 321 ? -74.077 54.892  66.656 1.00 95.25  ? 329 HIS C CA  1 
ATOM   9750  C C   . HIS C 1 321 ? -73.789 53.491  67.177 1.00 90.02  ? 329 HIS C C   1 
ATOM   9751  O O   . HIS C 1 321 ? -72.863 53.311  67.969 1.00 65.85  ? 329 HIS C O   1 
ATOM   9752  C CB  . HIS C 1 321 ? -75.185 55.714  67.331 1.00 87.72  ? 329 HIS C CB  1 
ATOM   9753  C CG  . HIS C 1 321 ? -74.874 57.179  67.443 1.00 88.05  ? 329 HIS C CG  1 
ATOM   9754  N ND1 . HIS C 1 321 ? -73.965 57.717  68.346 1.00 130.27 ? 329 HIS C ND1 1 
ATOM   9755  C CD2 . HIS C 1 321 ? -75.334 58.226  66.743 1.00 103.29 ? 329 HIS C CD2 1 
ATOM   9756  C CE1 . HIS C 1 321 ? -73.899 59.041  68.211 1.00 140.48 ? 329 HIS C CE1 1 
ATOM   9757  N NE2 . HIS C 1 321 ? -74.743 59.381  67.252 1.00 125.67 ? 329 HIS C NE2 1 
ATOM   9758  N N   . GLN C 1 322 ? -74.542 52.515  66.655 1.00 91.54  ? 330 GLN C N   1 
ATOM   9759  C CA  . GLN C 1 322 ? -74.357 51.124  67.035 1.00 89.79  ? 330 GLN C CA  1 
ATOM   9760  C C   . GLN C 1 322 ? -72.932 50.668  66.733 1.00 85.14  ? 330 GLN C C   1 
ATOM   9761  O O   . GLN C 1 322 ? -72.302 50.021  67.570 1.00 74.80  ? 330 GLN C O   1 
ATOM   9762  C CB  . GLN C 1 322 ? -75.344 50.236  66.283 1.00 99.88  ? 330 GLN C CB  1 
ATOM   9763  C CG  . GLN C 1 322 ? -75.409 48.827  66.848 1.00 116.84 ? 330 GLN C CG  1 
ATOM   9764  C CD  . GLN C 1 322 ? -75.837 48.816  68.300 1.00 122.32 ? 330 GLN C CD  1 
ATOM   9765  O OE1 . GLN C 1 322 ? -76.820 49.481  68.658 1.00 101.99 ? 330 GLN C OE1 1 
ATOM   9766  N NE2 . GLN C 1 322 ? -75.117 48.074  69.144 1.00 119.02 ? 330 GLN C NE2 1 
ATOM   9767  N N   . VAL C 1 323 ? -72.418 51.042  65.551 1.00 76.03  ? 331 VAL C N   1 
ATOM   9768  C CA  . VAL C 1 323 ? -71.074 50.644  65.162 1.00 86.19  ? 331 VAL C CA  1 
ATOM   9769  C C   . VAL C 1 323 ? -70.103 51.031  66.269 1.00 95.47  ? 331 VAL C C   1 
ATOM   9770  O O   . VAL C 1 323 ? -69.263 50.233  66.685 1.00 78.99  ? 331 VAL C O   1 
ATOM   9771  C CB  . VAL C 1 323 ? -70.645 51.294  63.836 1.00 79.36  ? 331 VAL C CB  1 
ATOM   9772  C CG1 . VAL C 1 323 ? -69.141 51.499  63.802 1.00 67.94  ? 331 VAL C CG1 1 
ATOM   9773  C CG2 . VAL C 1 323 ? -71.135 50.542  62.602 1.00 101.63 ? 331 VAL C CG2 1 
ATOM   9774  N N   . VAL C 1 324 ? -70.249 52.268  66.759 1.00 87.25  ? 332 VAL C N   1 
ATOM   9775  C CA  . VAL C 1 324 ? -69.314 52.739  67.765 1.00 94.60  ? 332 VAL C CA  1 
ATOM   9776  C C   . VAL C 1 324 ? -69.575 52.073  69.113 1.00 104.21 ? 332 VAL C C   1 
ATOM   9777  O O   . VAL C 1 324 ? -68.634 51.837  69.881 1.00 88.08  ? 332 VAL C O   1 
ATOM   9778  C CB  . VAL C 1 324 ? -69.201 54.262  67.928 1.00 98.31  ? 332 VAL C CB  1 
ATOM   9779  C CG1 . VAL C 1 324 ? -68.149 54.554  69.002 1.00 69.68  ? 332 VAL C CG1 1 
ATOM   9780  C CG2 . VAL C 1 324 ? -68.823 54.955  66.624 1.00 121.71 ? 332 VAL C CG2 1 
ATOM   9781  N N   . ALA C 1 325 ? -70.857 51.831  69.414 1.00 110.38 ? 333 ALA C N   1 
ATOM   9782  C CA  . ALA C 1 325 ? -71.243 51.149  70.642 1.00 104.05 ? 333 ALA C CA  1 
ATOM   9783  C C   . ALA C 1 325 ? -70.570 49.784  70.689 1.00 106.85 ? 333 ALA C C   1 
ATOM   9784  O O   . ALA C 1 325 ? -69.941 49.429  71.688 1.00 97.02  ? 333 ALA C O   1 
ATOM   9785  C CB  . ALA C 1 325 ? -72.736 50.987  70.683 1.00 87.25  ? 333 ALA C CB  1 
ATOM   9786  N N   . ASN C 1 326 ? -70.688 49.063  69.572 1.00 90.59  ? 334 ASN C N   1 
ATOM   9787  C CA  . ASN C 1 326 ? -70.154 47.723  69.434 1.00 87.46  ? 334 ASN C CA  1 
ATOM   9788  C C   . ASN C 1 326 ? -68.643 47.756  69.674 1.00 104.63 ? 334 ASN C C   1 
ATOM   9789  O O   . ASN C 1 326 ? -68.100 46.951  70.421 1.00 121.52 ? 334 ASN C O   1 
ATOM   9790  C CB  . ASN C 1 326 ? -70.552 47.139  68.077 1.00 87.31  ? 334 ASN C CB  1 
ATOM   9791  C CG  . ASN C 1 326 ? -72.027 46.779  67.981 1.00 93.52  ? 334 ASN C CG  1 
ATOM   9792  O OD1 . ASN C 1 326 ? -72.729 46.649  69.011 1.00 86.57  ? 334 ASN C OD1 1 
ATOM   9793  N ND2 . ASN C 1 326 ? -72.516 46.637  66.750 1.00 64.57  ? 334 ASN C ND2 1 
ATOM   9794  N N   . CYS C 1 327 ? -67.963 48.703  69.028 1.00 100.03 ? 335 CYS C N   1 
ATOM   9795  C CA  . CYS C 1 327 ? -66.527 48.835  69.180 1.00 101.85 ? 335 CYS C CA  1 
ATOM   9796  C C   . CYS C 1 327 ? -66.168 49.015  70.669 1.00 124.43 ? 335 CYS C C   1 
ATOM   9797  O O   . CYS C 1 327 ? -65.244 48.383  71.193 1.00 97.34  ? 335 CYS C O   1 
ATOM   9798  C CB  . CYS C 1 327 ? -66.039 49.988  68.305 1.00 86.96  ? 335 CYS C CB  1 
ATOM   9799  S SG  . CYS C 1 327 ? -64.261 50.262  68.496 1.00 91.18  ? 335 CYS C SG  1 
ATOM   9800  N N   . ARG C 1 328 ? -66.917 49.885  71.363 1.00 128.10 ? 336 ARG C N   1 
ATOM   9801  C CA  . ARG C 1 328 ? -66.635 50.151  72.765 1.00 122.53 ? 336 ARG C CA  1 
ATOM   9802  C C   . ARG C 1 328 ? -66.828 48.863  73.551 1.00 119.89 ? 336 ARG C C   1 
ATOM   9803  O O   . ARG C 1 328 ? -65.958 48.521  74.349 1.00 94.56  ? 336 ARG C O   1 
ATOM   9804  C CB  . ARG C 1 328 ? -67.410 51.312  73.394 1.00 113.98 ? 336 ARG C CB  1 
ATOM   9805  C CG  . ARG C 1 328 ? -67.009 52.632  72.756 1.00 123.70 ? 336 ARG C CG  1 
ATOM   9806  C CD  . ARG C 1 328 ? -67.210 53.869  73.599 1.00 118.91 ? 336 ARG C CD  1 
ATOM   9807  N NE  . ARG C 1 328 ? -67.793 54.930  72.764 1.00 126.76 ? 336 ARG C NE  1 
ATOM   9808  C CZ  . ARG C 1 328 ? -67.220 56.033  72.275 1.00 130.89 ? 336 ARG C CZ  1 
ATOM   9809  N NH1 . ARG C 1 328 ? -65.917 56.227  72.332 1.00 118.81 ? 336 ARG C NH1 1 
ATOM   9810  N NH2 . ARG C 1 328 ? -67.966 56.962  71.703 1.00 144.16 ? 336 ARG C NH2 1 
ATOM   9811  N N   . ALA C 1 329 ? -67.938 48.151  73.274 1.00 110.01 ? 337 ALA C N   1 
ATOM   9812  C CA  . ALA C 1 329 ? -68.273 46.907  73.964 1.00 112.24 ? 337 ALA C CA  1 
ATOM   9813  C C   . ALA C 1 329 ? -67.134 45.911  73.822 1.00 90.97  ? 337 ALA C C   1 
ATOM   9814  O O   . ALA C 1 329 ? -66.645 45.370  74.823 1.00 99.66  ? 337 ALA C O   1 
ATOM   9815  C CB  . ALA C 1 329 ? -69.566 46.313  73.450 1.00 104.60 ? 337 ALA C CB  1 
ATOM   9816  N N   . LEU C 1 330 ? -66.750 45.693  72.565 1.00 66.59  ? 338 LEU C N   1 
ATOM   9817  C CA  . LEU C 1 330 ? -65.637 44.813  72.245 1.00 74.64  ? 338 LEU C CA  1 
ATOM   9818  C C   . LEU C 1 330 ? -64.343 45.238  72.954 1.00 81.91  ? 338 LEU C C   1 
ATOM   9819  O O   . LEU C 1 330 ? -63.678 44.394  73.577 1.00 69.36  ? 338 LEU C O   1 
ATOM   9820  C CB  . LEU C 1 330 ? -65.468 44.765  70.737 1.00 79.25  ? 338 LEU C CB  1 
ATOM   9821  C CG  . LEU C 1 330 ? -64.326 43.891  70.242 1.00 77.83  ? 338 LEU C CG  1 
ATOM   9822  C CD1 . LEU C 1 330 ? -64.947 42.559  70.475 1.00 80.98  ? 338 LEU C CD1 1 
ATOM   9823  C CD2 . LEU C 1 330 ? -64.194 44.067  68.727 1.00 86.54  ? 338 LEU C CD2 1 
ATOM   9824  N N   . SER C 1 331 ? -64.020 46.549  72.912 1.00 62.86  ? 339 SER C N   1 
ATOM   9825  C CA  . SER C 1 331 ? -62.836 47.048  73.594 1.00 67.08  ? 339 SER C CA  1 
ATOM   9826  C C   . SER C 1 331 ? -62.937 46.743  75.093 1.00 96.10  ? 339 SER C C   1 
ATOM   9827  O O   . SER C 1 331 ? -62.025 46.208  75.716 1.00 93.92  ? 339 SER C O   1 
ATOM   9828  C CB  . SER C 1 331 ? -62.676 48.520  73.417 1.00 79.23  ? 339 SER C CB  1 
ATOM   9829  O OG  . SER C 1 331 ? -61.653 49.074  74.271 1.00 71.57  ? 339 SER C OG  1 
ATOM   9830  N N   . GLU C 1 332 ? -64.062 47.116  75.696 1.00 122.97 ? 340 GLU C N   1 
ATOM   9831  C CA  . GLU C 1 332 ? -64.206 46.974  77.131 1.00 119.68 ? 340 GLU C CA  1 
ATOM   9832  C C   . GLU C 1 332 ? -64.019 45.496  77.485 1.00 117.75 ? 340 GLU C C   1 
ATOM   9833  O O   . GLU C 1 332 ? -63.292 45.167  78.423 1.00 132.86 ? 340 GLU C O   1 
ATOM   9834  C CB  . GLU C 1 332 ? -65.538 47.628  77.509 1.00 101.47 ? 340 GLU C CB  1 
ATOM   9835  C CG  . GLU C 1 332 ? -65.683 47.818  79.009 1.00 97.26  ? 340 GLU C CG  1 
ATOM   9836  C CD  . GLU C 1 332 ? -66.914 48.667  79.276 1.00 131.85 ? 340 GLU C CD  1 
ATOM   9837  O OE1 . GLU C 1 332 ? -67.800 48.796  78.393 1.00 127.08 ? 340 GLU C OE1 1 
ATOM   9838  O OE2 . GLU C 1 332 ? -66.953 49.235  80.379 1.00 164.12 ? 340 GLU C OE2 1 
ATOM   9839  N N   . ALA C 1 333 ? -64.660 44.604  76.712 1.00 91.08  ? 341 ALA C N   1 
ATOM   9840  C CA  . ALA C 1 333 ? -64.634 43.173  76.978 1.00 88.93  ? 341 ALA C CA  1 
ATOM   9841  C C   . ALA C 1 333 ? -63.199 42.642  76.972 1.00 97.43  ? 341 ALA C C   1 
ATOM   9842  O O   . ALA C 1 333 ? -62.782 41.920  77.878 1.00 93.46  ? 341 ALA C O   1 
ATOM   9843  C CB  . ALA C 1 333 ? -65.518 42.450  75.995 1.00 78.99  ? 341 ALA C CB  1 
ATOM   9844  N N   . LEU C 1 334 ? -62.431 43.016  75.948 1.00 80.87  ? 342 LEU C N   1 
ATOM   9845  C CA  . LEU C 1 334 ? -61.057 42.542  75.866 1.00 81.82  ? 342 LEU C CA  1 
ATOM   9846  C C   . LEU C 1 334 ? -60.239 43.115  77.027 1.00 69.24  ? 342 LEU C C   1 
ATOM   9847  O O   . LEU C 1 334 ? -59.365 42.460  77.581 1.00 58.45  ? 342 LEU C O   1 
ATOM   9848  C CB  . LEU C 1 334 ? -60.453 42.856  74.501 1.00 71.35  ? 342 LEU C CB  1 
ATOM   9849  C CG  . LEU C 1 334 ? -61.158 42.117  73.371 1.00 80.27  ? 342 LEU C CG  1 
ATOM   9850  C CD1 . LEU C 1 334 ? -60.853 42.697  72.003 1.00 85.88  ? 342 LEU C CD1 1 
ATOM   9851  C CD2 . LEU C 1 334 ? -60.749 40.677  73.478 1.00 74.79  ? 342 LEU C CD2 1 
ATOM   9852  N N   . THR C 1 335 ? -60.540 44.359  77.385 1.00 64.58  ? 343 THR C N   1 
ATOM   9853  C CA  . THR C 1 335 ? -59.766 45.020  78.421 1.00 74.12  ? 343 THR C CA  1 
ATOM   9854  C C   . THR C 1 335 ? -60.000 44.286  79.727 1.00 69.09  ? 343 THR C C   1 
ATOM   9855  O O   . THR C 1 335 ? -59.026 44.103  80.452 1.00 57.23  ? 343 THR C O   1 
ATOM   9856  C CB  . THR C 1 335 ? -60.086 46.502  78.629 1.00 61.22  ? 343 THR C CB  1 
ATOM   9857  O OG1 . THR C 1 335 ? -59.970 47.108  77.341 1.00 62.47  ? 343 THR C OG1 1 
ATOM   9858  C CG2 . THR C 1 335 ? -59.207 47.068  79.749 1.00 33.24  ? 343 THR C CG2 1 
ATOM   9859  N N   . GLU C 1 336 ? -61.278 43.929  79.997 1.00 56.76  ? 344 GLU C N   1 
ATOM   9860  C CA  . GLU C 1 336 ? -61.666 43.166  81.166 1.00 70.50  ? 344 GLU C CA  1 
ATOM   9861  C C   . GLU C 1 336 ? -60.909 41.842  81.190 1.00 100.16 ? 344 GLU C C   1 
ATOM   9862  O O   . GLU C 1 336 ? -60.421 41.421  82.256 1.00 89.48  ? 344 GLU C O   1 
ATOM   9863  C CB  . GLU C 1 336 ? -63.181 42.987  81.154 1.00 74.62  ? 344 GLU C CB  1 
ATOM   9864  C CG  . GLU C 1 336 ? -63.921 44.254  81.560 1.00 95.75  ? 344 GLU C CG  1 
ATOM   9865  C CD  . GLU C 1 336 ? -65.390 44.210  81.236 1.00 95.05  ? 344 GLU C CD  1 
ATOM   9866  O OE1 . GLU C 1 336 ? -65.809 43.356  80.416 1.00 79.27  ? 344 GLU C OE1 1 
ATOM   9867  O OE2 . GLU C 1 336 ? -66.086 45.071  81.803 1.00 105.19 ? 344 GLU C OE2 1 
ATOM   9868  N N   . LEU C 1 337 ? -60.810 41.225  79.990 1.00 92.75  ? 345 LEU C N   1 
ATOM   9869  C CA  . LEU C 1 337 ? -60.105 39.959  79.815 1.00 76.22  ? 345 LEU C CA  1 
ATOM   9870  C C   . LEU C 1 337 ? -58.584 40.155  79.863 1.00 91.82  ? 345 LEU C C   1 
ATOM   9871  O O   . LEU C 1 337 ? -57.841 39.236  79.520 1.00 123.82 ? 345 LEU C O   1 
ATOM   9872  C CB  . LEU C 1 337 ? -60.513 39.364  78.474 1.00 64.29  ? 345 LEU C CB  1 
ATOM   9873  C CG  . LEU C 1 337 ? -61.849 38.638  78.410 1.00 81.47  ? 345 LEU C CG  1 
ATOM   9874  C CD1 . LEU C 1 337 ? -62.313 38.558  76.965 1.00 97.58  ? 345 LEU C CD1 1 
ATOM   9875  C CD2 . LEU C 1 337 ? -61.670 37.263  78.965 1.00 92.33  ? 345 LEU C CD2 1 
ATOM   9876  N N   . GLY C 1 338 ? -58.121 41.370  80.204 1.00 77.85  ? 346 GLY C N   1 
ATOM   9877  C CA  . GLY C 1 338 ? -56.715 41.670  80.409 1.00 68.63  ? 346 GLY C CA  1 
ATOM   9878  C C   . GLY C 1 338 ? -55.918 42.028  79.142 1.00 83.45  ? 346 GLY C C   1 
ATOM   9879  O O   . GLY C 1 338 ? -54.683 41.986  79.193 1.00 84.53  ? 346 GLY C O   1 
ATOM   9880  N N   . TYR C 1 339 ? -56.593 42.276  78.006 1.00 66.71  ? 347 TYR C N   1 
ATOM   9881  C CA  . TYR C 1 339 ? -55.863 42.615  76.789 1.00 72.40  ? 347 TYR C CA  1 
ATOM   9882  C C   . TYR C 1 339 ? -55.557 44.115  76.778 1.00 103.21 ? 347 TYR C C   1 
ATOM   9883  O O   . TYR C 1 339 ? -56.354 44.909  77.303 1.00 117.29 ? 347 TYR C O   1 
ATOM   9884  C CB  . TYR C 1 339 ? -56.717 42.304  75.565 1.00 58.65  ? 347 TYR C CB  1 
ATOM   9885  C CG  . TYR C 1 339 ? -56.904 40.852  75.172 1.00 64.56  ? 347 TYR C CG  1 
ATOM   9886  C CD1 . TYR C 1 339 ? -57.924 40.068  75.698 1.00 80.94  ? 347 TYR C CD1 1 
ATOM   9887  C CD2 . TYR C 1 339 ? -56.098 40.292  74.190 1.00 76.23  ? 347 TYR C CD2 1 
ATOM   9888  C CE1 . TYR C 1 339 ? -58.090 38.749  75.294 1.00 91.48  ? 347 TYR C CE1 1 
ATOM   9889  C CE2 . TYR C 1 339 ? -56.246 38.976  73.780 1.00 86.00  ? 347 TYR C CE2 1 
ATOM   9890  C CZ  . TYR C 1 339 ? -57.285 38.215  74.295 1.00 106.01 ? 347 TYR C CZ  1 
ATOM   9891  O OH  . TYR C 1 339 ? -57.419 36.935  73.802 1.00 85.62  ? 347 TYR C OH  1 
ATOM   9892  N N   . LYS C 1 340 ? -54.428 44.497  76.145 1.00 75.06  ? 348 LYS C N   1 
ATOM   9893  C CA  . LYS C 1 340 ? -54.075 45.904  75.999 1.00 84.91  ? 348 LYS C CA  1 
ATOM   9894  C C   . LYS C 1 340 ? -54.712 46.472  74.733 1.00 115.76 ? 348 LYS C C   1 
ATOM   9895  O O   . LYS C 1 340 ? -54.460 45.978  73.619 1.00 153.35 ? 348 LYS C O   1 
ATOM   9896  C CB  . LYS C 1 340 ? -52.567 46.130  75.880 1.00 70.24  ? 348 LYS C CB  1 
ATOM   9897  C CG  . LYS C 1 340 ? -52.276 47.652  75.985 1.00 53.11  ? 348 LYS C CG  1 
ATOM   9898  C CD  . LYS C 1 340 ? -51.000 48.210  75.371 1.00 55.36  ? 348 LYS C CD  1 
ATOM   9899  C CE  . LYS C 1 340 ? -49.628 47.915  75.915 1.00 73.17  ? 348 LYS C CE  1 
ATOM   9900  N NZ  . LYS C 1 340 ? -49.295 48.539  77.207 1.00 74.05  ? 348 LYS C NZ  1 
ATOM   9901  N N   . ILE C 1 341 ? -55.500 47.552  74.907 1.00 87.48  ? 349 ILE C N   1 
ATOM   9902  C CA  . ILE C 1 341 ? -56.044 48.245  73.751 1.00 98.72  ? 349 ILE C CA  1 
ATOM   9903  C C   . ILE C 1 341 ? -55.232 49.520  73.589 1.00 96.88  ? 349 ILE C C   1 
ATOM   9904  O O   . ILE C 1 341 ? -55.266 50.355  74.481 1.00 118.38 ? 349 ILE C O   1 
ATOM   9905  C CB  . ILE C 1 341 ? -57.546 48.545  73.941 1.00 110.87 ? 349 ILE C CB  1 
ATOM   9906  C CG1 . ILE C 1 341 ? -58.373 47.256  74.051 1.00 122.83 ? 349 ILE C CG1 1 
ATOM   9907  C CG2 . ILE C 1 341 ? -58.084 49.404  72.799 1.00 122.07 ? 349 ILE C CG2 1 
ATOM   9908  C CD1 . ILE C 1 341 ? -58.205 46.323  72.857 1.00 115.09 ? 349 ILE C CD1 1 
ATOM   9909  N N   . VAL C 1 342 ? -54.529 49.685  72.455 1.00 105.51 ? 350 VAL C N   1 
ATOM   9910  C CA  . VAL C 1 342 ? -53.665 50.843  72.254 1.00 81.79  ? 350 VAL C CA  1 
ATOM   9911  C C   . VAL C 1 342 ? -54.530 52.082  72.404 1.00 88.11  ? 350 VAL C C   1 
ATOM   9912  O O   . VAL C 1 342 ? -55.636 52.159  71.828 1.00 110.81 ? 350 VAL C O   1 
ATOM   9913  C CB  . VAL C 1 342 ? -52.993 50.912  70.872 1.00 95.94  ? 350 VAL C CB  1 
ATOM   9914  C CG1 . VAL C 1 342 ? -52.232 52.234  70.710 1.00 103.75 ? 350 VAL C CG1 1 
ATOM   9915  C CG2 . VAL C 1 342 ? -52.101 49.715  70.592 1.00 86.96  ? 350 VAL C CG2 1 
ATOM   9916  N N   . THR C 1 343 ? -53.984 53.055  73.141 1.00 73.90  ? 351 THR C N   1 
ATOM   9917  C CA  . THR C 1 343 ? -54.684 54.309  73.395 1.00 105.85 ? 351 THR C CA  1 
ATOM   9918  C C   . THR C 1 343 ? -55.775 54.122  74.456 1.00 106.75 ? 351 THR C C   1 
ATOM   9919  O O   . THR C 1 343 ? -56.367 55.095  74.903 1.00 119.85 ? 351 THR C O   1 
ATOM   9920  C CB  . THR C 1 343 ? -55.256 54.911  72.109 1.00 106.14 ? 351 THR C CB  1 
ATOM   9921  O OG1 . THR C 1 343 ? -55.564 56.236  72.479 1.00 132.36 ? 351 THR C OG1 1 
ATOM   9922  C CG2 . THR C 1 343 ? -56.526 54.232  71.610 1.00 93.46  ? 351 THR C CG2 1 
ATOM   9923  N N   . GLY C 1 344 ? -56.033 52.889  74.898 1.00 76.30  ? 352 GLY C N   1 
ATOM   9924  C CA  . GLY C 1 344 ? -56.955 52.711  76.013 1.00 69.16  ? 352 GLY C CA  1 
ATOM   9925  C C   . GLY C 1 344 ? -58.319 52.268  75.494 1.00 95.53  ? 352 GLY C C   1 
ATOM   9926  O O   . GLY C 1 344 ? -59.111 51.647  76.176 1.00 120.27 ? 352 GLY C O   1 
ATOM   9927  N N   . GLY C 1 345 ? -58.601 52.574  74.240 1.00 103.58 ? 353 GLY C N   1 
ATOM   9928  C CA  . GLY C 1 345 ? -59.948 52.351  73.753 1.00 87.18  ? 353 GLY C CA  1 
ATOM   9929  C C   . GLY C 1 345 ? -60.104 53.017  72.389 1.00 89.02  ? 353 GLY C C   1 
ATOM   9930  O O   . GLY C 1 345 ? -59.140 53.176  71.635 1.00 114.20 ? 353 GLY C O   1 
ATOM   9931  N N   . SER C 1 346 ? -61.335 53.446  72.117 1.00 87.02  ? 354 SER C N   1 
ATOM   9932  C CA  . SER C 1 346 ? -61.721 53.879  70.792 1.00 91.58  ? 354 SER C CA  1 
ATOM   9933  C C   . SER C 1 346 ? -62.830 54.932  70.841 1.00 92.04  ? 354 SER C C   1 
ATOM   9934  O O   . SER C 1 346 ? -63.756 54.872  71.650 1.00 123.28 ? 354 SER C O   1 
ATOM   9935  C CB  . SER C 1 346 ? -62.127 52.694  69.931 1.00 79.73  ? 354 SER C CB  1 
ATOM   9936  O OG  . SER C 1 346 ? -62.442 53.163  68.624 1.00 79.59  ? 354 SER C OG  1 
ATOM   9937  N N   . ASP C 1 347 ? -62.711 55.900  69.927 1.00 79.98  ? 355 ASP C N   1 
ATOM   9938  C CA  . ASP C 1 347 ? -63.714 56.909  69.660 1.00 64.16  ? 355 ASP C CA  1 
ATOM   9939  C C   . ASP C 1 347 ? -64.505 56.513  68.422 1.00 63.28  ? 355 ASP C C   1 
ATOM   9940  O O   . ASP C 1 347 ? -65.436 57.239  68.090 1.00 72.07  ? 355 ASP C O   1 
ATOM   9941  C CB  . ASP C 1 347 ? -63.064 58.265  69.471 1.00 68.01  ? 355 ASP C CB  1 
ATOM   9942  C CG  . ASP C 1 347 ? -62.188 58.714  70.638 1.00 100.24 ? 355 ASP C CG  1 
ATOM   9943  O OD1 . ASP C 1 347 ? -62.544 58.344  71.772 1.00 99.95  ? 355 ASP C OD1 1 
ATOM   9944  O OD2 . ASP C 1 347 ? -61.169 59.453  70.421 1.00 111.88 ? 355 ASP C OD2 1 
ATOM   9945  N N   . ASN C 1 348 ? -64.134 55.399  67.756 1.00 55.35  ? 356 ASN C N   1 
ATOM   9946  C CA  . ASN C 1 348 ? -64.619 55.087  66.402 1.00 67.85  ? 356 ASN C CA  1 
ATOM   9947  C C   . ASN C 1 348 ? -64.962 53.598  66.271 1.00 85.63  ? 356 ASN C C   1 
ATOM   9948  O O   . ASN C 1 348 ? -65.316 52.930  67.253 1.00 109.70 ? 356 ASN C O   1 
ATOM   9949  C CB  . ASN C 1 348 ? -63.640 55.513  65.297 1.00 62.01  ? 356 ASN C CB  1 
ATOM   9950  C CG  . ASN C 1 348 ? -62.207 55.041  65.521 1.00 80.28  ? 356 ASN C CG  1 
ATOM   9951  O OD1 . ASN C 1 348 ? -61.972 53.858  65.782 1.00 73.86  ? 356 ASN C OD1 1 
ATOM   9952  N ND2 . ASN C 1 348 ? -61.216 55.935  65.524 1.00 66.50  ? 356 ASN C ND2 1 
ATOM   9953  N N   . HIS C 1 349 ? -64.768 53.058  65.060 1.00 68.10  ? 357 HIS C N   1 
ATOM   9954  C CA  . HIS C 1 349 ? -65.231 51.720  64.710 1.00 90.66  ? 357 HIS C CA  1 
ATOM   9955  C C   . HIS C 1 349 ? -64.146 50.639  64.884 1.00 100.93 ? 357 HIS C C   1 
ATOM   9956  O O   . HIS C 1 349 ? -64.397 49.445  64.617 1.00 85.51  ? 357 HIS C O   1 
ATOM   9957  C CB  . HIS C 1 349 ? -65.658 51.720  63.237 1.00 83.43  ? 357 HIS C CB  1 
ATOM   9958  C CG  . HIS C 1 349 ? -64.532 52.098  62.332 1.00 90.28  ? 357 HIS C CG  1 
ATOM   9959  N ND1 . HIS C 1 349 ? -63.773 53.248  62.496 1.00 101.20 ? 357 HIS C ND1 1 
ATOM   9960  C CD2 . HIS C 1 349 ? -63.961 51.406  61.333 1.00 84.37  ? 357 HIS C CD2 1 
ATOM   9961  C CE1 . HIS C 1 349 ? -62.851 53.305  61.534 1.00 95.65  ? 357 HIS C CE1 1 
ATOM   9962  N NE2 . HIS C 1 349 ? -62.901 52.166  60.855 1.00 85.77  ? 357 HIS C NE2 1 
ATOM   9963  N N   . LEU C 1 350 ? -62.919 51.034  65.273 1.00 65.85  ? 358 LEU C N   1 
ATOM   9964  C CA  . LEU C 1 350 ? -61.845 50.048  65.347 1.00 66.27  ? 358 LEU C CA  1 
ATOM   9965  C C   . LEU C 1 350 ? -61.044 50.196  66.637 1.00 84.74  ? 358 LEU C C   1 
ATOM   9966  O O   . LEU C 1 350 ? -60.987 51.276  67.237 1.00 96.60  ? 358 LEU C O   1 
ATOM   9967  C CB  . LEU C 1 350 ? -60.917 50.022  64.126 1.00 67.91  ? 358 LEU C CB  1 
ATOM   9968  C CG  . LEU C 1 350 ? -60.077 51.274  63.867 1.00 83.18  ? 358 LEU C CG  1 
ATOM   9969  C CD1 . LEU C 1 350 ? -58.832 51.454  64.727 1.00 69.81  ? 358 LEU C CD1 1 
ATOM   9970  C CD2 . LEU C 1 350 ? -59.753 51.384  62.383 1.00 99.63  ? 358 LEU C CD2 1 
ATOM   9971  N N   . ILE C 1 351 ? -60.367 49.096  66.995 1.00 91.58  ? 359 ILE C N   1 
ATOM   9972  C CA  . ILE C 1 351 ? -59.374 49.090  68.059 1.00 91.99  ? 359 ILE C CA  1 
ATOM   9973  C C   . ILE C 1 351 ? -58.110 48.415  67.557 1.00 75.22  ? 359 ILE C C   1 
ATOM   9974  O O   . ILE C 1 351 ? -58.144 47.573  66.639 1.00 61.49  ? 359 ILE C O   1 
ATOM   9975  C CB  . ILE C 1 351 ? -59.897 48.332  69.287 1.00 111.93 ? 359 ILE C CB  1 
ATOM   9976  C CG1 . ILE C 1 351 ? -60.488 46.950  68.862 1.00 100.96 ? 359 ILE C CG1 1 
ATOM   9977  C CG2 . ILE C 1 351 ? -60.856 49.214  70.102 1.00 86.83  ? 359 ILE C CG2 1 
ATOM   9978  C CD1 . ILE C 1 351 ? -61.066 46.164  70.027 1.00 136.67 ? 359 ILE C CD1 1 
ATOM   9979  N N   . LEU C 1 352 ? -57.009 48.841  68.174 1.00 73.17  ? 360 LEU C N   1 
ATOM   9980  C CA  . LEU C 1 352 ? -55.750 48.185  67.895 1.00 87.57  ? 360 LEU C CA  1 
ATOM   9981  C C   . LEU C 1 352 ? -55.339 47.419  69.146 1.00 118.90 ? 360 LEU C C   1 
ATOM   9982  O O   . LEU C 1 352 ? -55.087 48.022  70.204 1.00 113.96 ? 360 LEU C O   1 
ATOM   9983  C CB  . LEU C 1 352 ? -54.687 49.197  67.502 1.00 69.04  ? 360 LEU C CB  1 
ATOM   9984  C CG  . LEU C 1 352 ? -53.318 48.611  67.155 1.00 74.13  ? 360 LEU C CG  1 
ATOM   9985  C CD1 . LEU C 1 352 ? -53.507 47.626  66.018 1.00 71.14  ? 360 LEU C CD1 1 
ATOM   9986  C CD2 . LEU C 1 352 ? -52.304 49.680  66.800 1.00 78.48  ? 360 LEU C CD2 1 
ATOM   9987  N N   . VAL C 1 353 ? -55.334 46.085  69.018 1.00 108.62 ? 361 VAL C N   1 
ATOM   9988  C CA  . VAL C 1 353 ? -55.088 45.257  70.187 1.00 107.53 ? 361 VAL C CA  1 
ATOM   9989  C C   . VAL C 1 353 ? -53.617 44.862  70.205 1.00 110.15 ? 361 VAL C C   1 
ATOM   9990  O O   . VAL C 1 353 ? -53.145 44.180  69.294 1.00 110.71 ? 361 VAL C O   1 
ATOM   9991  C CB  . VAL C 1 353 ? -55.932 43.975  70.240 1.00 99.69  ? 361 VAL C CB  1 
ATOM   9992  C CG1 . VAL C 1 353 ? -55.599 43.202  71.505 1.00 94.32  ? 361 VAL C CG1 1 
ATOM   9993  C CG2 . VAL C 1 353 ? -57.428 44.239  70.071 1.00 74.79  ? 361 VAL C CG2 1 
ATOM   9994  N N   . ASP C 1 354 ? -52.933 45.254  71.285 1.00 96.29  ? 362 ASP C N   1 
ATOM   9995  C CA  . ASP C 1 354 ? -51.538 44.909  71.490 1.00 76.18  ? 362 ASP C CA  1 
ATOM   9996  C C   . ASP C 1 354 ? -51.451 43.488  72.046 1.00 89.96  ? 362 ASP C C   1 
ATOM   9997  O O   . ASP C 1 354 ? -51.553 43.297  73.251 1.00 106.99 ? 362 ASP C O   1 
ATOM   9998  C CB  . ASP C 1 354 ? -50.921 45.891  72.469 1.00 64.95  ? 362 ASP C CB  1 
ATOM   9999  C CG  . ASP C 1 354 ? -49.411 45.906  72.458 1.00 90.23  ? 362 ASP C CG  1 
ATOM   10000 O OD1 . ASP C 1 354 ? -48.821 44.871  72.027 1.00 112.88 ? 362 ASP C OD1 1 
ATOM   10001 O OD2 . ASP C 1 354 ? -48.856 46.953  72.827 1.00 98.81  ? 362 ASP C OD2 1 
ATOM   10002 N N   . LEU C 1 355 ? -51.281 42.495  71.181 1.00 81.65  ? 363 LEU C N   1 
ATOM   10003 C CA  . LEU C 1 355 ? -51.194 41.115  71.644 1.00 89.63  ? 363 LEU C CA  1 
ATOM   10004 C C   . LEU C 1 355 ? -50.001 40.888  72.592 1.00 93.49  ? 363 LEU C C   1 
ATOM   10005 O O   . LEU C 1 355 ? -49.873 39.815  73.188 1.00 72.51  ? 363 LEU C O   1 
ATOM   10006 C CB  . LEU C 1 355 ? -51.166 40.159  70.436 1.00 70.67  ? 363 LEU C CB  1 
ATOM   10007 C CG  . LEU C 1 355 ? -52.513 39.948  69.740 1.00 78.29  ? 363 LEU C CG  1 
ATOM   10008 C CD1 . LEU C 1 355 ? -52.502 38.774  68.837 1.00 82.70  ? 363 LEU C CD1 1 
ATOM   10009 C CD2 . LEU C 1 355 ? -53.684 39.687  70.674 1.00 108.44 ? 363 LEU C CD2 1 
ATOM   10010 N N   . ARG C 1 356 ? -49.049 41.832  72.702 1.00 79.39  ? 364 ARG C N   1 
ATOM   10011 C CA  . ARG C 1 356 ? -47.959 41.604  73.654 1.00 77.54  ? 364 ARG C CA  1 
ATOM   10012 C C   . ARG C 1 356 ? -48.507 41.385  75.079 1.00 98.07  ? 364 ARG C C   1 
ATOM   10013 O O   . ARG C 1 356 ? -47.883 40.738  75.878 1.00 88.92  ? 364 ARG C O   1 
ATOM   10014 C CB  . ARG C 1 356 ? -46.856 42.667  73.564 1.00 73.88  ? 364 ARG C CB  1 
ATOM   10015 C CG  . ARG C 1 356 ? -46.156 42.748  72.212 1.00 64.00  ? 364 ARG C CG  1 
ATOM   10016 C CD  . ARG C 1 356 ? -45.274 43.995  72.134 1.00 63.33  ? 364 ARG C CD  1 
ATOM   10017 N NE  . ARG C 1 356 ? -46.046 45.240  72.000 1.00 68.38  ? 364 ARG C NE  1 
ATOM   10018 C CZ  . ARG C 1 356 ? -45.620 46.442  71.561 1.00 84.02  ? 364 ARG C CZ  1 
ATOM   10019 N NH1 . ARG C 1 356 ? -44.405 46.655  71.104 1.00 102.77 ? 364 ARG C NH1 1 
ATOM   10020 N NH2 . ARG C 1 356 ? -46.439 47.473  71.515 1.00 138.44 ? 364 ARG C NH2 1 
ATOM   10021 N N   . SER C 1 357 ? -49.737 41.820  75.366 1.00 124.72 ? 365 SER C N   1 
ATOM   10022 C CA  . SER C 1 357 ? -50.434 41.676  76.637 1.00 104.23 ? 365 SER C CA  1 
ATOM   10023 C C   . SER C 1 357 ? -50.808 40.214  76.915 1.00 97.49  ? 365 SER C C   1 
ATOM   10024 O O   . SER C 1 357 ? -51.105 39.845  78.047 1.00 119.65 ? 365 SER C O   1 
ATOM   10025 C CB  . SER C 1 357 ? -51.698 42.514  76.597 1.00 120.64 ? 365 SER C CB  1 
ATOM   10026 O OG  . SER C 1 357 ? -52.607 42.025  75.603 1.00 99.80  ? 365 SER C OG  1 
ATOM   10027 N N   . LYS C 1 358 ? -50.922 39.392  75.868 1.00 65.52  ? 366 LYS C N   1 
ATOM   10028 C CA  . LYS C 1 358 ? -51.222 37.977  76.055 1.00 79.20  ? 366 LYS C CA  1 
ATOM   10029 C C   . LYS C 1 358 ? -50.038 37.086  75.615 1.00 94.56  ? 366 LYS C C   1 
ATOM   10030 O O   . LYS C 1 358 ? -50.228 35.890  75.305 1.00 86.02  ? 366 LYS C O   1 
ATOM   10031 C CB  . LYS C 1 358 ? -52.488 37.611  75.251 1.00 83.90  ? 366 LYS C CB  1 
ATOM   10032 C CG  . LYS C 1 358 ? -53.864 37.562  75.904 1.00 79.20  ? 366 LYS C CG  1 
ATOM   10033 C CD  . LYS C 1 358 ? -54.218 38.654  76.909 1.00 103.35 ? 366 LYS C CD  1 
ATOM   10034 C CE  . LYS C 1 358 ? -55.276 38.293  77.946 1.00 85.94  ? 366 LYS C CE  1 
ATOM   10035 N NZ  . LYS C 1 358 ? -54.987 38.893  79.269 1.00 60.11  ? 366 LYS C NZ  1 
ATOM   10036 N N   . GLY C 1 359 ? -48.832 37.688  75.501 1.00 89.02  ? 367 GLY C N   1 
ATOM   10037 C CA  . GLY C 1 359 ? -47.563 37.054  75.147 1.00 81.23  ? 367 GLY C CA  1 
ATOM   10038 C C   . GLY C 1 359 ? -47.515 36.460  73.730 1.00 109.41 ? 367 GLY C C   1 
ATOM   10039 O O   . GLY C 1 359 ? -47.132 35.306  73.550 1.00 103.11 ? 367 GLY C O   1 
ATOM   10040 N N   . THR C 1 360 ? -47.902 37.215  72.696 1.00 108.37 ? 368 THR C N   1 
ATOM   10041 C CA  . THR C 1 360 ? -47.903 36.645  71.354 1.00 94.36  ? 368 THR C CA  1 
ATOM   10042 C C   . THR C 1 360 ? -47.881 37.812  70.380 1.00 87.63  ? 368 THR C C   1 
ATOM   10043 O O   . THR C 1 360 ? -47.807 38.936  70.860 1.00 100.77 ? 368 THR C O   1 
ATOM   10044 C CB  . THR C 1 360 ? -49.116 35.726  71.157 1.00 96.16  ? 368 THR C CB  1 
ATOM   10045 O OG1 . THR C 1 360 ? -49.205 35.158  69.854 1.00 74.15  ? 368 THR C OG1 1 
ATOM   10046 C CG2 . THR C 1 360 ? -50.438 36.460  71.223 1.00 103.07 ? 368 THR C CG2 1 
ATOM   10047 N N   . ASP C 1 361 ? -47.978 37.541  69.071 1.00 68.96  ? 369 ASP C N   1 
ATOM   10048 C CA  . ASP C 1 361 ? -47.979 38.576  68.047 1.00 63.63  ? 369 ASP C CA  1 
ATOM   10049 C C   . ASP C 1 361 ? -49.172 38.397  67.091 1.00 88.96  ? 369 ASP C C   1 
ATOM   10050 O O   . ASP C 1 361 ? -49.690 37.281  66.876 1.00 81.35  ? 369 ASP C O   1 
ATOM   10051 C CB  . ASP C 1 361 ? -46.657 38.572  67.297 1.00 52.38  ? 369 ASP C CB  1 
ATOM   10052 C CG  . ASP C 1 361 ? -46.426 37.289  66.503 1.00 72.52  ? 369 ASP C CG  1 
ATOM   10053 O OD1 . ASP C 1 361 ? -46.962 37.132  65.341 1.00 54.42  ? 369 ASP C OD1 1 
ATOM   10054 O OD2 . ASP C 1 361 ? -45.738 36.418  67.081 1.00 96.68  ? 369 ASP C OD2 1 
ATOM   10055 N N   . GLY C 1 362 ? -49.577 39.519  66.461 1.00 93.70  ? 370 GLY C N   1 
ATOM   10056 C CA  . GLY C 1 362 ? -50.687 39.521  65.523 1.00 80.50  ? 370 GLY C CA  1 
ATOM   10057 C C   . GLY C 1 362 ? -50.402 38.631  64.312 1.00 85.63  ? 370 GLY C C   1 
ATOM   10058 O O   . GLY C 1 362 ? -51.333 38.221  63.602 1.00 81.88  ? 370 GLY C O   1 
ATOM   10059 N N   . GLY C 1 363 ? -49.098 38.394  64.054 1.00 83.50  ? 371 GLY C N   1 
ATOM   10060 C CA  . GLY C 1 363 ? -48.659 37.676  62.870 1.00 90.56  ? 371 GLY C CA  1 
ATOM   10061 C C   . GLY C 1 363 ? -49.306 36.301  62.876 1.00 94.52  ? 371 GLY C C   1 
ATOM   10062 O O   . GLY C 1 363 ? -49.901 35.859  61.882 1.00 89.86  ? 371 GLY C O   1 
ATOM   10063 N N   . ARG C 1 364 ? -49.169 35.672  64.055 1.00 82.44  ? 372 ARG C N   1 
ATOM   10064 C CA  . ARG C 1 364 ? -49.590 34.307  64.318 1.00 71.94  ? 372 ARG C CA  1 
ATOM   10065 C C   . ARG C 1 364 ? -51.101 34.304  64.499 1.00 84.12  ? 372 ARG C C   1 
ATOM   10066 O O   . ARG C 1 364 ? -51.794 33.521  63.836 1.00 101.53 ? 372 ARG C O   1 
ATOM   10067 C CB  . ARG C 1 364 ? -48.922 33.741  65.580 1.00 58.13  ? 372 ARG C CB  1 
ATOM   10068 C CG  . ARG C 1 364 ? -47.424 33.564  65.386 1.00 80.01  ? 372 ARG C CG  1 
ATOM   10069 C CD  . ARG C 1 364 ? -46.505 33.542  66.606 1.00 91.18  ? 372 ARG C CD  1 
ATOM   10070 N NE  . ARG C 1 364 ? -45.117 33.718  66.163 1.00 80.67  ? 372 ARG C NE  1 
ATOM   10071 C CZ  . ARG C 1 364 ? -44.390 32.774  65.550 1.00 110.16 ? 372 ARG C CZ  1 
ATOM   10072 N NH1 . ARG C 1 364 ? -44.747 31.494  65.538 1.00 112.37 ? 372 ARG C NH1 1 
ATOM   10073 N NH2 . ARG C 1 364 ? -43.245 33.094  64.979 1.00 128.94 ? 372 ARG C NH2 1 
ATOM   10074 N N   . ALA C 1 365 ? -51.567 35.207  65.377 1.00 74.06  ? 373 ALA C N   1 
ATOM   10075 C CA  . ALA C 1 365 ? -52.954 35.229  65.803 1.00 56.26  ? 373 ALA C CA  1 
ATOM   10076 C C   . ALA C 1 365 ? -53.854 35.347  64.566 1.00 75.52  ? 373 ALA C C   1 
ATOM   10077 O O   . ALA C 1 365 ? -54.776 34.553  64.370 1.00 62.37  ? 373 ALA C O   1 
ATOM   10078 C CB  . ALA C 1 365 ? -53.145 36.372  66.758 1.00 44.29  ? 373 ALA C CB  1 
ATOM   10079 N N   . GLU C 1 366 ? -53.529 36.325  63.712 1.00 79.28  ? 374 GLU C N   1 
ATOM   10080 C CA  . GLU C 1 366 ? -54.295 36.549  62.507 1.00 65.16  ? 374 GLU C CA  1 
ATOM   10081 C C   . GLU C 1 366 ? -54.561 35.217  61.802 1.00 82.78  ? 374 GLU C C   1 
ATOM   10082 O O   . GLU C 1 366 ? -55.711 34.958  61.423 1.00 99.71  ? 374 GLU C O   1 
ATOM   10083 C CB  . GLU C 1 366 ? -53.557 37.595  61.679 1.00 88.15  ? 374 GLU C CB  1 
ATOM   10084 C CG  . GLU C 1 366 ? -53.897 37.587  60.186 1.00 112.21 ? 374 GLU C CG  1 
ATOM   10085 C CD  . GLU C 1 366 ? -53.049 38.595  59.450 1.00 98.15  ? 374 GLU C CD  1 
ATOM   10086 O OE1 . GLU C 1 366 ? -51.768 38.514  59.504 1.00 77.14  ? 374 GLU C OE1 1 
ATOM   10087 O OE2 . GLU C 1 366 ? -53.711 39.513  58.914 1.00 78.24  ? 374 GLU C OE2 1 
ATOM   10088 N N   . LYS C 1 367 ? -53.506 34.396  61.606 1.00 75.89  ? 375 LYS C N   1 
ATOM   10089 C CA  . LYS C 1 367 ? -53.569 33.181  60.797 1.00 78.73  ? 375 LYS C CA  1 
ATOM   10090 C C   . LYS C 1 367 ? -54.535 32.136  61.368 1.00 83.09  ? 375 LYS C C   1 
ATOM   10091 O O   . LYS C 1 367 ? -55.300 31.513  60.604 1.00 77.10  ? 375 LYS C O   1 
ATOM   10092 C CB  . LYS C 1 367 ? -52.171 32.570  60.620 1.00 66.56  ? 375 LYS C CB  1 
ATOM   10093 C CG  . LYS C 1 367 ? -51.487 32.782  59.271 1.00 54.00  ? 375 LYS C CG  1 
ATOM   10094 C CD  . LYS C 1 367 ? -52.521 32.685  58.167 1.00 45.62  ? 375 LYS C CD  1 
ATOM   10095 C CE  . LYS C 1 367 ? -51.863 33.084  56.838 1.00 56.65  ? 375 LYS C CE  1 
ATOM   10096 N NZ  . LYS C 1 367 ? -52.840 33.715  55.902 1.00 48.06  ? 375 LYS C NZ  1 
ATOM   10097 N N   . VAL C 1 368 ? -54.425 31.920  62.696 1.00 68.47  ? 376 VAL C N   1 
ATOM   10098 C CA  . VAL C 1 368 ? -55.272 31.048  63.485 1.00 64.06  ? 376 VAL C CA  1 
ATOM   10099 C C   . VAL C 1 368 ? -56.714 31.507  63.302 1.00 77.37  ? 376 VAL C C   1 
ATOM   10100 O O   . VAL C 1 368 ? -57.583 30.745  62.861 1.00 85.32  ? 376 VAL C O   1 
ATOM   10101 C CB  . VAL C 1 368 ? -54.914 31.261  64.979 1.00 63.33  ? 376 VAL C CB  1 
ATOM   10102 C CG1 . VAL C 1 368 ? -55.845 30.494  65.934 1.00 47.08  ? 376 VAL C CG1 1 
ATOM   10103 C CG2 . VAL C 1 368 ? -53.427 31.175  65.338 1.00 51.93  ? 376 VAL C CG2 1 
ATOM   10104 N N   . LEU C 1 369 ? -56.955 32.759  63.740 1.00 87.84  ? 377 LEU C N   1 
ATOM   10105 C CA  . LEU C 1 369 ? -58.295 33.315  63.829 1.00 100.50 ? 377 LEU C CA  1 
ATOM   10106 C C   . LEU C 1 369 ? -58.934 33.149  62.469 1.00 118.37 ? 377 LEU C C   1 
ATOM   10107 O O   . LEU C 1 369 ? -60.123 32.835  62.393 1.00 110.98 ? 377 LEU C O   1 
ATOM   10108 C CB  . LEU C 1 369 ? -58.268 34.780  64.226 1.00 89.52  ? 377 LEU C CB  1 
ATOM   10109 C CG  . LEU C 1 369 ? -57.921 35.057  65.690 1.00 98.92  ? 377 LEU C CG  1 
ATOM   10110 C CD1 . LEU C 1 369 ? -57.314 36.449  65.870 1.00 114.20 ? 377 LEU C CD1 1 
ATOM   10111 C CD2 . LEU C 1 369 ? -59.245 34.974  66.403 1.00 126.86 ? 377 LEU C CD2 1 
ATOM   10112 N N   . GLU C 1 370 ? -58.080 33.300  61.440 1.00 102.60 ? 378 GLU C N   1 
ATOM   10113 C CA  . GLU C 1 370 ? -58.533 33.151  60.066 1.00 108.27 ? 378 GLU C CA  1 
ATOM   10114 C C   . GLU C 1 370 ? -59.096 31.749  59.870 1.00 85.12  ? 378 GLU C C   1 
ATOM   10115 O O   . GLU C 1 370 ? -60.165 31.592  59.260 1.00 91.78  ? 378 GLU C O   1 
ATOM   10116 C CB  . GLU C 1 370 ? -57.429 33.463  59.051 1.00 101.42 ? 378 GLU C CB  1 
ATOM   10117 C CG  . GLU C 1 370 ? -57.799 33.177  57.592 1.00 81.02  ? 378 GLU C CG  1 
ATOM   10118 C CD  . GLU C 1 370 ? -56.625 33.660  56.757 1.00 115.45 ? 378 GLU C CD  1 
ATOM   10119 O OE1 . GLU C 1 370 ? -55.671 34.176  57.401 1.00 125.14 ? 378 GLU C OE1 1 
ATOM   10120 O OE2 . GLU C 1 370 ? -56.650 33.529  55.516 1.00 114.69 ? 378 GLU C OE2 1 
ATOM   10121 N N   . ALA C 1 371 ? -58.340 30.762  60.359 1.00 71.54  ? 379 ALA C N   1 
ATOM   10122 C CA  . ALA C 1 371 ? -58.695 29.370  60.181 1.00 88.92  ? 379 ALA C CA  1 
ATOM   10123 C C   . ALA C 1 371 ? -59.954 29.043  60.998 1.00 121.45 ? 379 ALA C C   1 
ATOM   10124 O O   . ALA C 1 371 ? -60.592 28.017  60.767 1.00 128.70 ? 379 ALA C O   1 
ATOM   10125 C CB  . ALA C 1 371 ? -57.514 28.510  60.553 1.00 104.28 ? 379 ALA C CB  1 
ATOM   10126 N N   . CYS C 1 372 ? -60.321 29.927  61.945 1.00 113.24 ? 380 CYS C N   1 
ATOM   10127 C CA  . CYS C 1 372 ? -61.522 29.744  62.749 1.00 117.07 ? 380 CYS C CA  1 
ATOM   10128 C C   . CYS C 1 372 ? -62.656 30.634  62.249 1.00 118.25 ? 380 CYS C C   1 
ATOM   10129 O O   . CYS C 1 372 ? -63.649 30.832  62.966 1.00 113.81 ? 380 CYS C O   1 
ATOM   10130 C CB  . CYS C 1 372 ? -61.279 30.072  64.212 1.00 93.14  ? 380 CYS C CB  1 
ATOM   10131 S SG  . CYS C 1 372 ? -59.942 29.056  64.868 1.00 127.30 ? 380 CYS C SG  1 
ATOM   10132 N N   . SER C 1 373 ? -62.486 31.176  61.028 1.00 83.66  ? 381 SER C N   1 
ATOM   10133 C CA  . SER C 1 373 ? -63.517 31.976  60.376 1.00 81.73  ? 381 SER C CA  1 
ATOM   10134 C C   . SER C 1 373 ? -63.749 33.319  61.052 1.00 104.18 ? 381 SER C C   1 
ATOM   10135 O O   . SER C 1 373 ? -64.824 33.914  60.874 1.00 123.30 ? 381 SER C O   1 
ATOM   10136 C CB  . SER C 1 373 ? -64.825 31.267  60.264 1.00 68.82  ? 381 SER C CB  1 
ATOM   10137 O OG  . SER C 1 373 ? -64.626 30.061  59.546 1.00 90.62  ? 381 SER C OG  1 
ATOM   10138 N N   . ILE C 1 374 ? -62.719 33.783  61.775 1.00 126.04 ? 382 ILE C N   1 
ATOM   10139 C CA  . ILE C 1 374 ? -62.704 35.107  62.371 1.00 132.27 ? 382 ILE C CA  1 
ATOM   10140 C C   . ILE C 1 374 ? -61.716 35.911  61.542 1.00 119.80 ? 382 ILE C C   1 
ATOM   10141 O O   . ILE C 1 374 ? -60.496 35.752  61.690 1.00 110.63 ? 382 ILE C O   1 
ATOM   10142 C CB  . ILE C 1 374 ? -62.301 35.031  63.858 1.00 129.48 ? 382 ILE C CB  1 
ATOM   10143 C CG1 . ILE C 1 374 ? -63.275 34.162  64.617 1.00 132.37 ? 382 ILE C CG1 1 
ATOM   10144 C CG2 . ILE C 1 374 ? -62.221 36.418  64.491 1.00 118.18 ? 382 ILE C CG2 1 
ATOM   10145 C CD1 . ILE C 1 374 ? -63.041 34.132  66.110 1.00 145.68 ? 382 ILE C CD1 1 
ATOM   10146 N N   . ALA C 1 375 ? -62.256 36.782  60.682 1.00 103.46 ? 383 ALA C N   1 
ATOM   10147 C CA  . ALA C 1 375 ? -61.384 37.630  59.888 1.00 101.64 ? 383 ALA C CA  1 
ATOM   10148 C C   . ALA C 1 375 ? -61.001 38.856  60.717 1.00 86.52  ? 383 ALA C C   1 
ATOM   10149 O O   . ALA C 1 375 ? -61.888 39.637  61.084 1.00 77.94  ? 383 ALA C O   1 
ATOM   10150 C CB  . ALA C 1 375 ? -62.051 37.999  58.560 1.00 103.15 ? 383 ALA C CB  1 
ATOM   10151 N N   . CYS C 1 376 ? -59.679 38.984  61.000 1.00 64.64  ? 384 CYS C N   1 
ATOM   10152 C CA  . CYS C 1 376 ? -59.073 40.256  61.343 1.00 63.43  ? 384 CYS C CA  1 
ATOM   10153 C C   . CYS C 1 376 ? -57.787 40.485  60.552 1.00 55.91  ? 384 CYS C C   1 
ATOM   10154 O O   . CYS C 1 376 ? -57.724 40.077  59.402 1.00 49.74  ? 384 CYS C O   1 
ATOM   10155 C CB  . CYS C 1 376 ? -58.957 40.357  62.837 1.00 67.80  ? 384 CYS C CB  1 
ATOM   10156 S SG  . CYS C 1 376 ? -57.637 39.297  63.442 1.00 116.54 ? 384 CYS C SG  1 
ATOM   10157 N N   . ASN C 1 377 ? -56.900 41.393  60.973 1.00 59.50  ? 385 ASN C N   1 
ATOM   10158 C CA  . ASN C 1 377 ? -55.735 41.713  60.132 1.00 85.98  ? 385 ASN C CA  1 
ATOM   10159 C C   . ASN C 1 377 ? -54.631 42.128  61.088 1.00 84.50  ? 385 ASN C C   1 
ATOM   10160 O O   . ASN C 1 377 ? -54.930 42.840  62.069 1.00 87.33  ? 385 ASN C O   1 
ATOM   10161 C CB  . ASN C 1 377 ? -55.963 42.679  58.954 1.00 77.61  ? 385 ASN C CB  1 
ATOM   10162 C CG  . ASN C 1 377 ? -56.299 44.084  59.418 1.00 109.85 ? 385 ASN C CG  1 
ATOM   10163 O OD1 . ASN C 1 377 ? -57.468 44.463  59.619 1.00 106.19 ? 385 ASN C OD1 1 
ATOM   10164 N ND2 . ASN C 1 377 ? -55.276 44.906  59.563 1.00 123.62 ? 385 ASN C ND2 1 
ATOM   10165 N N   . LYS C 1 378 ? -53.386 41.642  60.844 1.00 69.40  ? 386 LYS C N   1 
ATOM   10166 C CA  . LYS C 1 378 ? -52.323 41.873  61.832 1.00 85.13  ? 386 LYS C CA  1 
ATOM   10167 C C   . LYS C 1 378 ? -52.015 43.376  61.776 1.00 92.53  ? 386 LYS C C   1 
ATOM   10168 O O   . LYS C 1 378 ? -52.713 44.099  61.081 1.00 115.40 ? 386 LYS C O   1 
ATOM   10169 C CB  . LYS C 1 378 ? -51.071 40.977  61.715 1.00 53.95  ? 386 LYS C CB  1 
ATOM   10170 C CG  . LYS C 1 378 ? -50.543 40.974  60.321 1.00 51.85  ? 386 LYS C CG  1 
ATOM   10171 C CD  . LYS C 1 378 ? -49.062 41.100  59.932 1.00 44.71  ? 386 LYS C CD  1 
ATOM   10172 C CE  . LYS C 1 378 ? -48.992 41.330  58.416 1.00 56.29  ? 386 LYS C CE  1 
ATOM   10173 N NZ  . LYS C 1 378 ? -49.153 40.192  57.479 1.00 42.58  ? 386 LYS C NZ  1 
ATOM   10174 N N   . ASN C 1 379 ? -51.045 43.875  62.538 1.00 72.21  ? 387 ASN C N   1 
ATOM   10175 C CA  . ASN C 1 379 ? -50.523 45.218  62.299 1.00 77.62  ? 387 ASN C CA  1 
ATOM   10176 C C   . ASN C 1 379 ? -49.728 45.710  63.522 1.00 73.14  ? 387 ASN C C   1 
ATOM   10177 O O   . ASN C 1 379 ? -50.009 45.400  64.684 1.00 84.05  ? 387 ASN C O   1 
ATOM   10178 C CB  . ASN C 1 379 ? -51.376 46.135  61.398 1.00 65.00  ? 387 ASN C CB  1 
ATOM   10179 C CG  . ASN C 1 379 ? -52.010 47.374  62.026 1.00 91.25  ? 387 ASN C CG  1 
ATOM   10180 O OD1 . ASN C 1 379 ? -51.700 47.764  63.174 1.00 76.29  ? 387 ASN C OD1 1 
ATOM   10181 N ND2 . ASN C 1 379 ? -52.892 47.999  61.261 1.00 97.38  ? 387 ASN C ND2 1 
ATOM   10182 N N   . THR C 1 380 ? -48.699 46.507  63.241 1.00 76.22  ? 388 THR C N   1 
ATOM   10183 C CA  . THR C 1 380 ? -47.815 47.026  64.266 1.00 88.89  ? 388 THR C CA  1 
ATOM   10184 C C   . THR C 1 380 ? -48.582 47.930  65.234 1.00 96.64  ? 388 THR C C   1 
ATOM   10185 O O   . THR C 1 380 ? -49.593 48.551  64.900 1.00 79.66  ? 388 THR C O   1 
ATOM   10186 C CB  . THR C 1 380 ? -46.608 47.732  63.655 1.00 91.38  ? 388 THR C CB  1 
ATOM   10187 O OG1 . THR C 1 380 ? -47.150 48.597  62.669 1.00 91.19  ? 388 THR C OG1 1 
ATOM   10188 C CG2 . THR C 1 380 ? -45.685 46.765  62.938 1.00 112.88 ? 388 THR C CG2 1 
ATOM   10189 N N   . CYS C 1 381 ? -48.146 47.880  66.497 1.00 89.75  ? 389 CYS C N   1 
ATOM   10190 C CA  . CYS C 1 381 ? -48.568 48.831  67.503 1.00 103.78 ? 389 CYS C CA  1 
ATOM   10191 C C   . CYS C 1 381 ? -47.432 49.815  67.684 1.00 111.58 ? 389 CYS C C   1 
ATOM   10192 O O   . CYS C 1 381 ? -46.298 49.457  67.413 1.00 124.98 ? 389 CYS C O   1 
ATOM   10193 C CB  . CYS C 1 381 ? -48.847 48.154  68.833 1.00 110.02 ? 389 CYS C CB  1 
ATOM   10194 S SG  . CYS C 1 381 ? -50.078 46.856  68.596 1.00 97.20  ? 389 CYS C SG  1 
ATOM   10195 N N   . PRO C 1 382 ? -47.714 51.066  68.094 1.00 120.65 ? 390 PRO C N   1 
ATOM   10196 C CA  . PRO C 1 382 ? -46.686 52.103  68.075 1.00 146.49 ? 390 PRO C CA  1 
ATOM   10197 C C   . PRO C 1 382 ? -45.393 51.613  68.729 1.00 142.14 ? 390 PRO C C   1 
ATOM   10198 O O   . PRO C 1 382 ? -45.436 51.115  69.870 1.00 123.18 ? 390 PRO C O   1 
ATOM   10199 C CB  . PRO C 1 382 ? -47.372 53.259  68.829 1.00 164.97 ? 390 PRO C CB  1 
ATOM   10200 C CG  . PRO C 1 382 ? -48.856 53.045  68.581 1.00 176.48 ? 390 PRO C CG  1 
ATOM   10201 C CD  . PRO C 1 382 ? -49.037 51.542  68.523 1.00 145.77 ? 390 PRO C CD  1 
ATOM   10202 N N   . GLY C 1 383 ? -44.274 51.767  67.974 1.00 98.34  ? 391 GLY C N   1 
ATOM   10203 C CA  . GLY C 1 383 ? -42.932 51.470  68.448 1.00 106.94 ? 391 GLY C CA  1 
ATOM   10204 C C   . GLY C 1 383 ? -42.587 49.981  68.371 1.00 115.73 ? 391 GLY C C   1 
ATOM   10205 O O   . GLY C 1 383 ? -41.667 49.528  69.048 1.00 102.37 ? 391 GLY C O   1 
ATOM   10206 N N   . ASP C 1 384 ? -43.368 49.201  67.610 1.00 128.57 ? 392 ASP C N   1 
ATOM   10207 C CA  . ASP C 1 384 ? -42.999 47.832  67.299 1.00 135.82 ? 392 ASP C CA  1 
ATOM   10208 C C   . ASP C 1 384 ? -41.570 47.789  66.773 1.00 150.25 ? 392 ASP C C   1 
ATOM   10209 O O   . ASP C 1 384 ? -41.158 48.661  65.998 1.00 92.71  ? 392 ASP C O   1 
ATOM   10210 C CB  . ASP C 1 384 ? -43.961 47.224  66.300 1.00 118.48 ? 392 ASP C CB  1 
ATOM   10211 C CG  . ASP C 1 384 ? -45.046 46.362  66.915 1.00 135.24 ? 392 ASP C CG  1 
ATOM   10212 O OD1 . ASP C 1 384 ? -45.201 46.393  68.139 1.00 137.72 ? 392 ASP C OD1 1 
ATOM   10213 O OD2 . ASP C 1 384 ? -45.680 45.643  66.138 1.00 156.02 ? 392 ASP C OD2 1 
ATOM   10214 N N   . ARG C 1 385 ? -40.854 46.750  67.219 1.00 158.22 ? 393 ARG C N   1 
ATOM   10215 C CA  . ARG C 1 385 ? -39.418 46.691  67.013 1.00 117.57 ? 393 ARG C CA  1 
ATOM   10216 C C   . ARG C 1 385 ? -39.083 46.227  65.585 1.00 85.33  ? 393 ARG C C   1 
ATOM   10217 O O   . ARG C 1 385 ? -37.955 46.390  65.137 1.00 119.65 ? 393 ARG C O   1 
ATOM   10218 C CB  . ARG C 1 385 ? -38.782 46.091  68.279 1.00 87.04  ? 393 ARG C CB  1 
ATOM   10219 C CG  . ARG C 1 385 ? -38.346 47.215  69.206 1.00 80.53  ? 393 ARG C CG  1 
ATOM   10220 C CD  . ARG C 1 385 ? -37.789 48.310  68.295 1.00 109.57 ? 393 ARG C CD  1 
ATOM   10221 N NE  . ARG C 1 385 ? -36.942 49.441  68.683 1.00 119.77 ? 393 ARG C NE  1 
ATOM   10222 C CZ  . ARG C 1 385 ? -35.912 49.938  67.971 1.00 127.28 ? 393 ARG C CZ  1 
ATOM   10223 N NH1 . ARG C 1 385 ? -35.556 49.477  66.773 1.00 101.79 ? 393 ARG C NH1 1 
ATOM   10224 N NH2 . ARG C 1 385 ? -35.224 50.950  68.464 1.00 137.69 ? 393 ARG C NH2 1 
ATOM   10225 N N   . SER C 1 386 ? -40.046 45.646  64.865 1.00 84.87  ? 394 SER C N   1 
ATOM   10226 C CA  . SER C 1 386 ? -39.900 45.213  63.475 1.00 89.23  ? 394 SER C CA  1 
ATOM   10227 C C   . SER C 1 386 ? -41.287 45.048  62.866 1.00 95.68  ? 394 SER C C   1 
ATOM   10228 O O   . SER C 1 386 ? -42.174 44.464  63.500 1.00 127.13 ? 394 SER C O   1 
ATOM   10229 C CB  . SER C 1 386 ? -39.153 43.888  63.366 1.00 80.05  ? 394 SER C CB  1 
ATOM   10230 O OG  . SER C 1 386 ? -39.272 43.350  62.062 1.00 63.50  ? 394 SER C OG  1 
ATOM   10231 N N   . ALA C 1 387 ? -41.481 45.580  61.651 1.00 99.82  ? 395 ALA C N   1 
ATOM   10232 C CA  . ALA C 1 387 ? -42.783 45.490  60.998 1.00 105.63 ? 395 ALA C CA  1 
ATOM   10233 C C   . ALA C 1 387 ? -43.074 44.048  60.568 1.00 94.56  ? 395 ALA C C   1 
ATOM   10234 O O   . ALA C 1 387 ? -44.220 43.738  60.244 1.00 70.79  ? 395 ALA C O   1 
ATOM   10235 C CB  . ALA C 1 387 ? -42.916 46.511  59.861 1.00 91.90  ? 395 ALA C CB  1 
ATOM   10236 N N   . LEU C 1 388 ? -42.030 43.194  60.586 1.00 99.38  ? 396 LEU C N   1 
ATOM   10237 C CA  . LEU C 1 388 ? -42.127 41.810  60.138 1.00 117.57 ? 396 LEU C CA  1 
ATOM   10238 C C   . LEU C 1 388 ? -42.767 40.939  61.223 1.00 121.95 ? 396 LEU C C   1 
ATOM   10239 O O   . LEU C 1 388 ? -43.288 39.869  60.900 1.00 126.13 ? 396 LEU C O   1 
ATOM   10240 C CB  . LEU C 1 388 ? -40.798 41.229  59.640 1.00 105.68 ? 396 LEU C CB  1 
ATOM   10241 C CG  . LEU C 1 388 ? -40.257 41.715  58.283 1.00 103.22 ? 396 LEU C CG  1 
ATOM   10242 C CD1 . LEU C 1 388 ? -39.003 40.922  57.872 1.00 90.99  ? 396 LEU C CD1 1 
ATOM   10243 C CD2 . LEU C 1 388 ? -41.209 41.745  57.079 1.00 87.09  ? 396 LEU C CD2 1 
ATOM   10244 N N   . ARG C 1 389 ? -42.686 41.358  62.505 1.00 95.24  ? 397 ARG C N   1 
ATOM   10245 C CA  . ARG C 1 389 ? -43.318 40.648  63.615 1.00 106.00 ? 397 ARG C CA  1 
ATOM   10246 C C   . ARG C 1 389 ? -44.277 41.575  64.387 1.00 134.59 ? 397 ARG C C   1 
ATOM   10247 O O   . ARG C 1 389 ? -43.983 42.002  65.518 1.00 118.16 ? 397 ARG C O   1 
ATOM   10248 C CB  . ARG C 1 389 ? -42.323 39.907  64.522 1.00 96.45  ? 397 ARG C CB  1 
ATOM   10249 C CG  . ARG C 1 389 ? -43.046 39.150  65.631 1.00 123.72 ? 397 ARG C CG  1 
ATOM   10250 C CD  . ARG C 1 389 ? -42.389 39.004  67.020 1.00 106.16 ? 397 ARG C CD  1 
ATOM   10251 N NE  . ARG C 1 389 ? -41.396 37.928  67.128 1.00 98.51  ? 397 ARG C NE  1 
ATOM   10252 C CZ  . ARG C 1 389 ? -41.683 36.627  67.284 1.00 130.42 ? 397 ARG C CZ  1 
ATOM   10253 N NH1 . ARG C 1 389 ? -42.921 36.179  67.180 1.00 139.06 ? 397 ARG C NH1 1 
ATOM   10254 N NH2 . ARG C 1 389 ? -40.722 35.761  67.532 1.00 130.04 ? 397 ARG C NH2 1 
ATOM   10255 N N   . PRO C 1 390 ? -45.464 41.866  63.791 1.00 121.88 ? 398 PRO C N   1 
ATOM   10256 C CA  . PRO C 1 390 ? -46.413 42.826  64.350 1.00 98.41  ? 398 PRO C CA  1 
ATOM   10257 C C   . PRO C 1 390 ? -47.017 42.344  65.663 1.00 84.38  ? 398 PRO C C   1 
ATOM   10258 O O   . PRO C 1 390 ? -47.466 41.210  65.790 1.00 82.26  ? 398 PRO C O   1 
ATOM   10259 C CB  . PRO C 1 390 ? -47.457 42.965  63.238 1.00 91.00  ? 398 PRO C CB  1 
ATOM   10260 C CG  . PRO C 1 390 ? -47.445 41.635  62.535 1.00 109.97 ? 398 PRO C CG  1 
ATOM   10261 C CD  . PRO C 1 390 ? -45.969 41.245  62.553 1.00 118.12 ? 398 PRO C CD  1 
ATOM   10262 N N   . SER C 1 391 ? -47.069 43.262  66.624 1.00 71.29  ? 399 SER C N   1 
ATOM   10263 C CA  . SER C 1 391 ? -47.634 42.988  67.932 1.00 80.82  ? 399 SER C CA  1 
ATOM   10264 C C   . SER C 1 391 ? -49.162 42.997  67.953 1.00 91.99  ? 399 SER C C   1 
ATOM   10265 O O   . SER C 1 391 ? -49.727 42.558  68.954 1.00 104.68 ? 399 SER C O   1 
ATOM   10266 C CB  . SER C 1 391 ? -47.175 43.999  68.899 1.00 71.94  ? 399 SER C CB  1 
ATOM   10267 O OG  . SER C 1 391 ? -45.778 43.916  69.046 1.00 84.20  ? 399 SER C OG  1 
ATOM   10268 N N   . GLY C 1 392 ? -49.791 43.557  66.906 1.00 69.47  ? 400 GLY C N   1 
ATOM   10269 C CA  . GLY C 1 392 ? -51.159 44.067  66.980 1.00 66.88  ? 400 GLY C CA  1 
ATOM   10270 C C   . GLY C 1 392 ? -52.159 43.336  66.079 1.00 78.21  ? 400 GLY C C   1 
ATOM   10271 O O   . GLY C 1 392 ? -51.780 42.740  65.072 1.00 61.95  ? 400 GLY C O   1 
ATOM   10272 N N   . LEU C 1 393 ? -53.440 43.382  66.480 1.00 85.59  ? 401 LEU C N   1 
ATOM   10273 C CA  . LEU C 1 393 ? -54.546 43.011  65.614 1.00 84.72  ? 401 LEU C CA  1 
ATOM   10274 C C   . LEU C 1 393 ? -55.446 44.233  65.469 1.00 93.94  ? 401 LEU C C   1 
ATOM   10275 O O   . LEU C 1 393 ? -55.788 44.877  66.489 1.00 56.36  ? 401 LEU C O   1 
ATOM   10276 C CB  . LEU C 1 393 ? -55.320 41.877  66.266 1.00 73.29  ? 401 LEU C CB  1 
ATOM   10277 C CG  . LEU C 1 393 ? -54.729 40.479  66.118 1.00 67.55  ? 401 LEU C CG  1 
ATOM   10278 C CD1 . LEU C 1 393 ? -55.724 39.540  66.716 1.00 65.54  ? 401 LEU C CD1 1 
ATOM   10279 C CD2 . LEU C 1 393 ? -54.588 40.149  64.638 1.00 94.10  ? 401 LEU C CD2 1 
ATOM   10280 N N   . ARG C 1 394 ? -55.765 44.561  64.202 1.00 74.01  ? 402 ARG C N   1 
ATOM   10281 C CA  . ARG C 1 394 ? -56.737 45.612  63.967 1.00 64.74  ? 402 ARG C CA  1 
ATOM   10282 C C   . ARG C 1 394 ? -58.120 44.964  63.866 1.00 69.08  ? 402 ARG C C   1 
ATOM   10283 O O   . ARG C 1 394 ? -58.351 44.126  62.978 1.00 66.52  ? 402 ARG C O   1 
ATOM   10284 C CB  . ARG C 1 394 ? -56.380 46.377  62.698 1.00 69.43  ? 402 ARG C CB  1 
ATOM   10285 C CG  . ARG C 1 394 ? -57.333 47.549  62.437 1.00 92.86  ? 402 ARG C CG  1 
ATOM   10286 C CD  . ARG C 1 394 ? -57.208 48.256  61.077 1.00 81.19  ? 402 ARG C CD  1 
ATOM   10287 N NE  . ARG C 1 394 ? -57.596 47.368  59.981 1.00 98.30  ? 402 ARG C NE  1 
ATOM   10288 C CZ  . ARG C 1 394 ? -57.482 47.735  58.711 1.00 105.64 ? 402 ARG C CZ  1 
ATOM   10289 N NH1 . ARG C 1 394 ? -57.152 48.972  58.381 1.00 111.66 ? 402 ARG C NH1 1 
ATOM   10290 N NH2 . ARG C 1 394 ? -57.696 46.856  57.751 1.00 135.43 ? 402 ARG C NH2 1 
ATOM   10291 N N   . LEU C 1 395 ? -59.044 45.413  64.730 1.00 66.64  ? 403 LEU C N   1 
ATOM   10292 C CA  . LEU C 1 395 ? -60.405 44.898  64.759 1.00 65.10  ? 403 LEU C CA  1 
ATOM   10293 C C   . LEU C 1 395 ? -61.379 46.060  64.571 1.00 70.58  ? 403 LEU C C   1 
ATOM   10294 O O   . LEU C 1 395 ? -61.195 47.147  65.141 1.00 63.71  ? 403 LEU C O   1 
ATOM   10295 C CB  . LEU C 1 395 ? -60.688 44.241  66.108 1.00 83.52  ? 403 LEU C CB  1 
ATOM   10296 C CG  . LEU C 1 395 ? -59.776 43.090  66.511 1.00 93.89  ? 403 LEU C CG  1 
ATOM   10297 C CD1 . LEU C 1 395 ? -60.180 42.689  67.921 1.00 116.26 ? 403 LEU C CD1 1 
ATOM   10298 C CD2 . LEU C 1 395 ? -59.974 41.992  65.509 1.00 74.88  ? 403 LEU C CD2 1 
ATOM   10299 N N   . GLY C 1 396 ? -62.408 45.828  63.751 1.00 53.34  ? 404 GLY C N   1 
ATOM   10300 C CA  . GLY C 1 396 ? -63.433 46.826  63.550 1.00 53.88  ? 404 GLY C CA  1 
ATOM   10301 C C   . GLY C 1 396 ? -64.815 46.180  63.543 1.00 111.33 ? 404 GLY C C   1 
ATOM   10302 O O   . GLY C 1 396 ? -64.983 44.970  63.284 1.00 141.43 ? 404 GLY C O   1 
ATOM   10303 N N   . THR C 1 397 ? -65.821 47.043  63.754 1.00 107.42 ? 405 THR C N   1 
ATOM   10304 C CA  . THR C 1 397 ? -67.193 46.580  63.913 1.00 92.18  ? 405 THR C CA  1 
ATOM   10305 C C   . THR C 1 397 ? -68.100 46.768  62.702 1.00 93.77  ? 405 THR C C   1 
ATOM   10306 O O   . THR C 1 397 ? -69.163 46.160  62.707 1.00 85.40  ? 405 THR C O   1 
ATOM   10307 C CB  . THR C 1 397 ? -67.760 47.212  65.176 1.00 85.58  ? 405 THR C CB  1 
ATOM   10308 O OG1 . THR C 1 397 ? -67.803 48.615  64.932 1.00 85.39  ? 405 THR C OG1 1 
ATOM   10309 C CG2 . THR C 1 397 ? -66.865 46.870  66.365 1.00 79.12  ? 405 THR C CG2 1 
ATOM   10310 N N   . PRO C 1 398 ? -67.766 47.613  61.681 1.00 90.21  ? 406 PRO C N   1 
ATOM   10311 C CA  . PRO C 1 398 ? -68.717 47.992  60.637 1.00 69.96  ? 406 PRO C CA  1 
ATOM   10312 C C   . PRO C 1 398 ? -69.383 46.788  59.989 1.00 71.18  ? 406 PRO C C   1 
ATOM   10313 O O   . PRO C 1 398 ? -70.618 46.705  59.942 1.00 51.64  ? 406 PRO C O   1 
ATOM   10314 C CB  . PRO C 1 398 ? -67.843 48.711  59.675 1.00 59.66  ? 406 PRO C CB  1 
ATOM   10315 C CG  . PRO C 1 398 ? -66.934 49.441  60.581 1.00 77.10  ? 406 PRO C CG  1 
ATOM   10316 C CD  . PRO C 1 398 ? -66.505 48.350  61.514 1.00 81.03  ? 406 PRO C CD  1 
ATOM   10317 N N   . ALA C 1 399 ? -68.555 45.833  59.554 1.00 71.70  ? 407 ALA C N   1 
ATOM   10318 C CA  . ALA C 1 399 ? -69.114 44.751  58.757 1.00 85.68  ? 407 ALA C CA  1 
ATOM   10319 C C   . ALA C 1 399 ? -70.194 43.991  59.533 1.00 99.03  ? 407 ALA C C   1 
ATOM   10320 O O   . ALA C 1 399 ? -71.323 43.857  59.054 1.00 91.62  ? 407 ALA C O   1 
ATOM   10321 C CB  . ALA C 1 399 ? -67.993 43.858  58.291 1.00 92.66  ? 407 ALA C CB  1 
ATOM   10322 N N   . LEU C 1 400 ? -69.833 43.496  60.729 1.00 101.80 ? 408 LEU C N   1 
ATOM   10323 C CA  . LEU C 1 400 ? -70.737 42.698  61.543 1.00 93.35  ? 408 LEU C CA  1 
ATOM   10324 C C   . LEU C 1 400 ? -71.942 43.538  61.955 1.00 104.73 ? 408 LEU C C   1 
ATOM   10325 O O   . LEU C 1 400 ? -73.041 43.013  62.066 1.00 116.09 ? 408 LEU C O   1 
ATOM   10326 C CB  . LEU C 1 400 ? -69.993 42.183  62.776 1.00 72.56  ? 408 LEU C CB  1 
ATOM   10327 C CG  . LEU C 1 400 ? -69.198 40.901  62.571 1.00 70.49  ? 408 LEU C CG  1 
ATOM   10328 C CD1 . LEU C 1 400 ? -68.481 40.532  63.848 1.00 88.40  ? 408 LEU C CD1 1 
ATOM   10329 C CD2 . LEU C 1 400 ? -70.128 39.790  62.126 1.00 54.36  ? 408 LEU C CD2 1 
ATOM   10330 N N   . THR C 1 401 ? -71.721 44.832  62.239 1.00 92.01  ? 409 THR C N   1 
ATOM   10331 C CA  . THR C 1 401 ? -72.801 45.685  62.712 1.00 70.68  ? 409 THR C CA  1 
ATOM   10332 C C   . THR C 1 401 ? -73.836 45.797  61.599 1.00 72.85  ? 409 THR C C   1 
ATOM   10333 O O   . THR C 1 401 ? -75.033 45.829  61.836 1.00 95.08  ? 409 THR C O   1 
ATOM   10334 C CB  . THR C 1 401 ? -72.309 47.056  63.177 1.00 70.16  ? 409 THR C CB  1 
ATOM   10335 O OG1 . THR C 1 401 ? -71.308 46.853  64.180 1.00 94.58  ? 409 THR C OG1 1 
ATOM   10336 C CG2 . THR C 1 401 ? -73.424 47.871  63.819 1.00 75.60  ? 409 THR C CG2 1 
ATOM   10337 N N   . SER C 1 402 ? -73.381 45.873  60.360 1.00 76.26  ? 410 SER C N   1 
ATOM   10338 C CA  . SER C 1 402 ? -74.293 45.974  59.238 1.00 78.16  ? 410 SER C CA  1 
ATOM   10339 C C   . SER C 1 402 ? -75.102 44.680  59.162 1.00 94.36  ? 410 SER C C   1 
ATOM   10340 O O   . SER C 1 402 ? -76.086 44.583  58.438 1.00 119.52 ? 410 SER C O   1 
ATOM   10341 C CB  . SER C 1 402 ? -73.505 46.191  57.958 1.00 88.68  ? 410 SER C CB  1 
ATOM   10342 O OG  . SER C 1 402 ? -72.863 47.466  57.911 1.00 83.13  ? 410 SER C OG  1 
ATOM   10343 N N   . ARG C 1 403 ? -74.655 43.647  59.884 1.00 80.74  ? 411 ARG C N   1 
ATOM   10344 C CA  . ARG C 1 403 ? -75.369 42.377  59.896 1.00 102.02 ? 411 ARG C CA  1 
ATOM   10345 C C   . ARG C 1 403 ? -76.432 42.402  61.011 1.00 112.76 ? 411 ARG C C   1 
ATOM   10346 O O   . ARG C 1 403 ? -77.387 41.605  61.045 1.00 106.62 ? 411 ARG C O   1 
ATOM   10347 C CB  . ARG C 1 403 ? -74.363 41.224  60.046 1.00 101.76 ? 411 ARG C CB  1 
ATOM   10348 C CG  . ARG C 1 403 ? -73.476 41.076  58.821 1.00 99.70  ? 411 ARG C CG  1 
ATOM   10349 C CD  . ARG C 1 403 ? -72.690 39.807  58.856 1.00 98.86  ? 411 ARG C CD  1 
ATOM   10350 N NE  . ARG C 1 403 ? -73.613 38.666  58.756 1.00 112.46 ? 411 ARG C NE  1 
ATOM   10351 C CZ  . ARG C 1 403 ? -73.197 37.425  58.582 1.00 128.03 ? 411 ARG C CZ  1 
ATOM   10352 N NH1 . ARG C 1 403 ? -71.893 37.181  58.485 1.00 131.49 ? 411 ARG C NH1 1 
ATOM   10353 N NH2 . ARG C 1 403 ? -74.082 36.444  58.534 1.00 115.22 ? 411 ARG C NH2 1 
ATOM   10354 N N   . GLY C 1 404 ? -76.272 43.317  61.966 1.00 80.33  ? 412 GLY C N   1 
ATOM   10355 C CA  . GLY C 1 404 ? -77.300 43.383  62.987 1.00 84.13  ? 412 GLY C CA  1 
ATOM   10356 C C   . GLY C 1 404 ? -76.762 43.243  64.411 1.00 78.61  ? 412 GLY C C   1 
ATOM   10357 O O   . GLY C 1 404 ? -77.459 43.576  65.365 1.00 79.07  ? 412 GLY C O   1 
ATOM   10358 N N   . LEU C 1 405 ? -75.511 42.801  64.551 1.00 76.39  ? 413 LEU C N   1 
ATOM   10359 C CA  . LEU C 1 405 ? -74.912 42.586  65.864 1.00 89.27  ? 413 LEU C CA  1 
ATOM   10360 C C   . LEU C 1 405 ? -75.034 43.829  66.754 1.00 101.91 ? 413 LEU C C   1 
ATOM   10361 O O   . LEU C 1 405 ? -74.818 44.965  66.291 1.00 100.37 ? 413 LEU C O   1 
ATOM   10362 C CB  . LEU C 1 405 ? -73.464 42.101  65.750 1.00 86.50  ? 413 LEU C CB  1 
ATOM   10363 C CG  . LEU C 1 405 ? -73.227 40.623  65.418 1.00 73.36  ? 413 LEU C CG  1 
ATOM   10364 C CD1 . LEU C 1 405 ? -73.473 40.243  63.960 1.00 77.94  ? 413 LEU C CD1 1 
ATOM   10365 C CD2 . LEU C 1 405 ? -71.796 40.310  65.739 1.00 81.80  ? 413 LEU C CD2 1 
ATOM   10366 N N   . LEU C 1 406 ? -75.353 43.584  68.043 1.00 75.06  ? 414 LEU C N   1 
ATOM   10367 C CA  . LEU C 1 406 ? -75.412 44.622  69.070 1.00 90.47  ? 414 LEU C CA  1 
ATOM   10368 C C   . LEU C 1 406 ? -74.373 44.364  70.157 1.00 100.39 ? 414 LEU C C   1 
ATOM   10369 O O   . LEU C 1 406 ? -73.555 43.436  69.976 1.00 110.97 ? 414 LEU C O   1 
ATOM   10370 C CB  . LEU C 1 406 ? -76.816 44.657  69.668 1.00 100.02 ? 414 LEU C CB  1 
ATOM   10371 C CG  . LEU C 1 406 ? -77.966 44.606  68.654 1.00 78.58  ? 414 LEU C CG  1 
ATOM   10372 C CD1 . LEU C 1 406 ? -79.241 43.974  69.113 1.00 77.78  ? 414 LEU C CD1 1 
ATOM   10373 C CD2 . LEU C 1 406 ? -78.085 46.019  68.074 1.00 96.93  ? 414 LEU C CD2 1 
ATOM   10374 N N   . GLU C 1 407 ? -74.435 45.151  71.276 1.00 63.77  ? 415 GLU C N   1 
ATOM   10375 C CA  . GLU C 1 407 ? -73.304 45.078  72.208 1.00 76.45  ? 415 GLU C CA  1 
ATOM   10376 C C   . GLU C 1 407 ? -73.093 43.677  72.769 1.00 90.00  ? 415 GLU C C   1 
ATOM   10377 O O   . GLU C 1 407 ? -71.973 43.185  72.837 1.00 90.99  ? 415 GLU C O   1 
ATOM   10378 C CB  . GLU C 1 407 ? -73.050 45.985  73.404 1.00 66.49  ? 415 GLU C CB  1 
ATOM   10379 C CG  . GLU C 1 407 ? -72.762 47.415  72.985 1.00 73.26  ? 415 GLU C CG  1 
ATOM   10380 C CD  . GLU C 1 407 ? -74.103 48.108  73.035 1.00 81.57  ? 415 GLU C CD  1 
ATOM   10381 O OE1 . GLU C 1 407 ? -75.209 47.681  72.519 1.00 68.35  ? 415 GLU C OE1 1 
ATOM   10382 O OE2 . GLU C 1 407 ? -73.912 49.164  73.702 1.00 54.84  ? 415 GLU C OE2 1 
ATOM   10383 N N   . LYS C 1 408 ? -74.178 43.033  73.198 1.00 102.94 ? 416 LYS C N   1 
ATOM   10384 C CA  . LYS C 1 408 ? -74.112 41.707  73.785 1.00 92.90  ? 416 LYS C CA  1 
ATOM   10385 C C   . LYS C 1 408 ? -73.432 40.776  72.791 1.00 81.75  ? 416 LYS C C   1 
ATOM   10386 O O   . LYS C 1 408 ? -72.537 40.040  73.192 1.00 87.43  ? 416 LYS C O   1 
ATOM   10387 C CB  . LYS C 1 408 ? -75.573 41.403  74.150 1.00 104.58 ? 416 LYS C CB  1 
ATOM   10388 C CG  . LYS C 1 408 ? -76.622 42.179  73.277 1.00 82.12  ? 416 LYS C CG  1 
ATOM   10389 C CD  . LYS C 1 408 ? -77.756 42.778  74.122 1.00 103.14 ? 416 LYS C CD  1 
ATOM   10390 C CE  . LYS C 1 408 ? -78.849 43.507  73.428 1.00 100.29 ? 416 LYS C CE  1 
ATOM   10391 N NZ  . LYS C 1 408 ? -79.904 42.516  73.253 1.00 135.97 ? 416 LYS C NZ  1 
ATOM   10392 N N   . ASP C 1 409 ? -73.849 40.836  71.509 1.00 63.47  ? 417 ASP C N   1 
ATOM   10393 C CA  . ASP C 1 409 ? -73.291 40.012  70.443 1.00 81.29  ? 417 ASP C CA  1 
ATOM   10394 C C   . ASP C 1 409 ? -71.778 40.209  70.318 1.00 113.50 ? 417 ASP C C   1 
ATOM   10395 O O   . ASP C 1 409 ? -71.017 39.247  70.186 1.00 114.81 ? 417 ASP C O   1 
ATOM   10396 C CB  . ASP C 1 409 ? -73.972 40.329  69.129 1.00 83.92  ? 417 ASP C CB  1 
ATOM   10397 C CG  . ASP C 1 409 ? -75.450 40.000  69.120 1.00 101.84 ? 417 ASP C CG  1 
ATOM   10398 O OD1 . ASP C 1 409 ? -75.806 38.914  69.591 1.00 112.70 ? 417 ASP C OD1 1 
ATOM   10399 O OD2 . ASP C 1 409 ? -76.231 40.814  68.641 1.00 109.88 ? 417 ASP C OD2 1 
ATOM   10400 N N   . PHE C 1 410 ? -71.354 41.481  70.339 1.00 95.90  ? 418 PHE C N   1 
ATOM   10401 C CA  . PHE C 1 410 ? -69.946 41.833  70.228 1.00 92.17  ? 418 PHE C CA  1 
ATOM   10402 C C   . PHE C 1 410 ? -69.156 41.277  71.409 1.00 85.99  ? 418 PHE C C   1 
ATOM   10403 O O   . PHE C 1 410 ? -67.933 41.155  71.327 1.00 107.91 ? 418 PHE C O   1 
ATOM   10404 C CB  . PHE C 1 410 ? -69.675 43.330  70.038 1.00 94.75  ? 418 PHE C CB  1 
ATOM   10405 C CG  . PHE C 1 410 ? -69.447 43.580  68.556 1.00 106.06 ? 418 PHE C CG  1 
ATOM   10406 C CD1 . PHE C 1 410 ? -68.185 43.397  68.002 1.00 87.61  ? 418 PHE C CD1 1 
ATOM   10407 C CD2 . PHE C 1 410 ? -70.512 43.912  67.712 1.00 114.04 ? 418 PHE C CD2 1 
ATOM   10408 C CE1 . PHE C 1 410 ? -68.025 43.488  66.633 1.00 80.15  ? 418 PHE C CE1 1 
ATOM   10409 C CE2 . PHE C 1 410 ? -70.328 44.079  66.347 1.00 84.75  ? 418 PHE C CE2 1 
ATOM   10410 C CZ  . PHE C 1 410 ? -69.090 43.850  65.814 1.00 90.35  ? 418 PHE C CZ  1 
ATOM   10411 N N   . GLN C 1 411 ? -69.850 40.998  72.517 1.00 72.49  ? 419 GLN C N   1 
ATOM   10412 C CA  . GLN C 1 411 ? -69.144 40.495  73.683 1.00 84.47  ? 419 GLN C CA  1 
ATOM   10413 C C   . GLN C 1 411 ? -68.819 39.032  73.402 1.00 99.75  ? 419 GLN C C   1 
ATOM   10414 O O   . GLN C 1 411 ? -67.742 38.552  73.770 1.00 84.35  ? 419 GLN C O   1 
ATOM   10415 C CB  . GLN C 1 411 ? -69.896 40.723  74.996 1.00 58.53  ? 419 GLN C CB  1 
ATOM   10416 C CG  . GLN C 1 411 ? -70.210 42.178  75.212 1.00 79.65  ? 419 GLN C CG  1 
ATOM   10417 C CD  . GLN C 1 411 ? -70.739 42.389  76.594 1.00 87.03  ? 419 GLN C CD  1 
ATOM   10418 O OE1 . GLN C 1 411 ? -70.154 41.907  77.562 1.00 91.80  ? 419 GLN C OE1 1 
ATOM   10419 N NE2 . GLN C 1 411 ? -71.847 43.111  76.664 1.00 105.08 ? 419 GLN C NE2 1 
ATOM   10420 N N   . LYS C 1 412 ? -69.768 38.364  72.713 1.00 74.19  ? 420 LYS C N   1 
ATOM   10421 C CA  . LYS C 1 412 ? -69.642 36.953  72.425 1.00 79.25  ? 420 LYS C CA  1 
ATOM   10422 C C   . LYS C 1 412 ? -68.450 36.856  71.479 1.00 115.61 ? 420 LYS C C   1 
ATOM   10423 O O   . LYS C 1 412 ? -67.675 35.905  71.531 1.00 104.58 ? 420 LYS C O   1 
ATOM   10424 C CB  . LYS C 1 412 ? -70.975 36.414  71.891 1.00 68.48  ? 420 LYS C CB  1 
ATOM   10425 C CG  . LYS C 1 412 ? -70.925 34.920  71.558 1.00 86.93  ? 420 LYS C CG  1 
ATOM   10426 C CD  . LYS C 1 412 ? -72.241 34.217  71.219 1.00 96.50  ? 420 LYS C CD  1 
ATOM   10427 C CE  . LYS C 1 412 ? -72.120 32.712  71.458 1.00 106.52 ? 420 LYS C CE  1 
ATOM   10428 N NZ  . LYS C 1 412 ? -72.809 31.760  70.558 1.00 89.89  ? 420 LYS C NZ  1 
ATOM   10429 N N   . VAL C 1 413 ? -68.312 37.884  70.637 1.00 143.15 ? 421 VAL C N   1 
ATOM   10430 C CA  . VAL C 1 413 ? -67.265 37.904  69.629 1.00 134.14 ? 421 VAL C CA  1 
ATOM   10431 C C   . VAL C 1 413 ? -65.917 38.001  70.329 1.00 106.42 ? 421 VAL C C   1 
ATOM   10432 O O   . VAL C 1 413 ? -64.998 37.248  70.001 1.00 90.10  ? 421 VAL C O   1 
ATOM   10433 C CB  . VAL C 1 413 ? -67.484 39.050  68.628 1.00 113.54 ? 421 VAL C CB  1 
ATOM   10434 C CG1 . VAL C 1 413 ? -66.278 39.288  67.736 1.00 96.86  ? 421 VAL C CG1 1 
ATOM   10435 C CG2 . VAL C 1 413 ? -68.763 38.835  67.825 1.00 102.05 ? 421 VAL C CG2 1 
ATOM   10436 N N   . ALA C 1 414 ? -65.844 38.911  71.306 1.00 87.11  ? 422 ALA C N   1 
ATOM   10437 C CA  . ALA C 1 414 ? -64.621 39.132  72.066 1.00 87.96  ? 422 ALA C CA  1 
ATOM   10438 C C   . ALA C 1 414 ? -64.168 37.813  72.691 1.00 100.33 ? 422 ALA C C   1 
ATOM   10439 O O   . ALA C 1 414 ? -62.970 37.510  72.743 1.00 85.32  ? 422 ALA C O   1 
ATOM   10440 C CB  . ALA C 1 414 ? -64.842 40.185  73.113 1.00 61.36  ? 422 ALA C CB  1 
ATOM   10441 N N   . HIS C 1 415 ? -65.148 36.990  73.087 1.00 92.57  ? 423 HIS C N   1 
ATOM   10442 C CA  . HIS C 1 415 ? -64.835 35.714  73.712 1.00 92.97  ? 423 HIS C CA  1 
ATOM   10443 C C   . HIS C 1 415 ? -64.301 34.735  72.663 1.00 101.02 ? 423 HIS C C   1 
ATOM   10444 O O   . HIS C 1 415 ? -63.367 33.970  72.962 1.00 77.94  ? 423 HIS C O   1 
ATOM   10445 C CB  . HIS C 1 415 ? -66.051 35.188  74.494 1.00 81.68  ? 423 HIS C CB  1 
ATOM   10446 C CG  . HIS C 1 415 ? -66.576 36.060  75.601 1.00 92.42  ? 423 HIS C CG  1 
ATOM   10447 N ND1 . HIS C 1 415 ? -65.797 36.603  76.620 1.00 94.70  ? 423 HIS C ND1 1 
ATOM   10448 C CD2 . HIS C 1 415 ? -67.860 36.452  75.834 1.00 76.27  ? 423 HIS C CD2 1 
ATOM   10449 C CE1 . HIS C 1 415 ? -66.572 37.320  77.437 1.00 72.10  ? 423 HIS C CE1 1 
ATOM   10450 N NE2 . HIS C 1 415 ? -67.823 37.236  76.973 1.00 82.01  ? 423 HIS C NE2 1 
ATOM   10451 N N   . PHE C 1 416 ? -64.904 34.766  71.457 1.00 83.30  ? 424 PHE C N   1 
ATOM   10452 C CA  . PHE C 1 416 ? -64.451 33.880  70.401 1.00 85.24  ? 424 PHE C CA  1 
ATOM   10453 C C   . PHE C 1 416 ? -63.037 34.268  69.974 1.00 83.62  ? 424 PHE C C   1 
ATOM   10454 O O   . PHE C 1 416 ? -62.184 33.418  69.713 1.00 65.93  ? 424 PHE C O   1 
ATOM   10455 C CB  . PHE C 1 416 ? -65.441 33.895  69.244 1.00 84.46  ? 424 PHE C CB  1 
ATOM   10456 C CG  . PHE C 1 416 ? -66.727 33.126  69.475 1.00 102.88 ? 424 PHE C CG  1 
ATOM   10457 C CD1 . PHE C 1 416 ? -66.799 32.120  70.436 1.00 116.74 ? 424 PHE C CD1 1 
ATOM   10458 C CD2 . PHE C 1 416 ? -67.878 33.486  68.785 1.00 115.24 ? 424 PHE C CD2 1 
ATOM   10459 C CE1 . PHE C 1 416 ? -67.993 31.452  70.643 1.00 155.94 ? 424 PHE C CE1 1 
ATOM   10460 C CE2 . PHE C 1 416 ? -69.064 32.815  68.985 1.00 132.83 ? 424 PHE C CE2 1 
ATOM   10461 C CZ  . PHE C 1 416 ? -69.119 31.806  69.919 1.00 180.50 ? 424 PHE C CZ  1 
ATOM   10462 N N   . ILE C 1 417 ? -62.779 35.571  69.906 1.00 67.03  ? 425 ILE C N   1 
ATOM   10463 C CA  . ILE C 1 417 ? -61.434 36.054  69.638 1.00 88.26  ? 425 ILE C CA  1 
ATOM   10464 C C   . ILE C 1 417 ? -60.493 35.500  70.706 1.00 95.22  ? 425 ILE C C   1 
ATOM   10465 O O   . ILE C 1 417 ? -59.430 34.979  70.349 1.00 103.13 ? 425 ILE C O   1 
ATOM   10466 C CB  . ILE C 1 417 ? -61.410 37.590  69.554 1.00 90.08  ? 425 ILE C CB  1 
ATOM   10467 C CG1 . ILE C 1 417 ? -62.104 38.045  68.238 1.00 73.96  ? 425 ILE C CG1 1 
ATOM   10468 C CG2 . ILE C 1 417 ? -59.983 38.134  69.747 1.00 63.28  ? 425 ILE C CG2 1 
ATOM   10469 C CD1 . ILE C 1 417 ? -62.399 39.535  68.170 1.00 65.25  ? 425 ILE C CD1 1 
ATOM   10470 N N   . HIS C 1 418 ? -60.911 35.591  71.986 1.00 71.18  ? 426 HIS C N   1 
ATOM   10471 C CA  . HIS C 1 418 ? -60.027 35.131  73.035 1.00 75.76  ? 426 HIS C CA  1 
ATOM   10472 C C   . HIS C 1 418 ? -59.676 33.659  72.820 1.00 91.68  ? 426 HIS C C   1 
ATOM   10473 O O   . HIS C 1 418 ? -58.516 33.272  72.852 1.00 102.54 ? 426 HIS C O   1 
ATOM   10474 C CB  . HIS C 1 418 ? -60.485 35.424  74.466 1.00 72.61  ? 426 HIS C CB  1 
ATOM   10475 C CG  . HIS C 1 418 ? -59.473 34.821  75.410 1.00 82.90  ? 426 HIS C CG  1 
ATOM   10476 N ND1 . HIS C 1 418 ? -58.139 35.205  75.400 1.00 101.17 ? 426 HIS C ND1 1 
ATOM   10477 C CD2 . HIS C 1 418 ? -59.506 33.787  76.267 1.00 88.91  ? 426 HIS C CD2 1 
ATOM   10478 C CE1 . HIS C 1 418 ? -57.412 34.514  76.271 1.00 85.72  ? 426 HIS C CE1 1 
ATOM   10479 N NE2 . HIS C 1 418 ? -58.226 33.632  76.807 1.00 114.06 ? 426 HIS C NE2 1 
ATOM   10480 N N   . ARG C 1 419 ? -60.675 32.808  72.619 1.00 77.78  ? 427 ARG C N   1 
ATOM   10481 C CA  . ARG C 1 419 ? -60.406 31.415  72.270 1.00 104.18 ? 427 ARG C CA  1 
ATOM   10482 C C   . ARG C 1 419 ? -59.377 31.295  71.133 1.00 120.28 ? 427 ARG C C   1 
ATOM   10483 O O   . ARG C 1 419 ? -58.403 30.539  71.224 1.00 126.47 ? 427 ARG C O   1 
ATOM   10484 C CB  . ARG C 1 419 ? -61.725 30.730  71.908 1.00 92.13  ? 427 ARG C CB  1 
ATOM   10485 C CG  . ARG C 1 419 ? -62.718 30.845  73.051 1.00 80.77  ? 427 ARG C CG  1 
ATOM   10486 C CD  . ARG C 1 419 ? -62.887 29.455  73.665 1.00 79.06  ? 427 ARG C CD  1 
ATOM   10487 N NE  . ARG C 1 419 ? -64.080 28.892  73.033 1.00 70.98  ? 427 ARG C NE  1 
ATOM   10488 C CZ  . ARG C 1 419 ? -64.145 27.716  72.403 1.00 54.66  ? 427 ARG C CZ  1 
ATOM   10489 N NH1 . ARG C 1 419 ? -63.040 26.935  72.377 1.00 37.63  ? 427 ARG C NH1 1 
ATOM   10490 N NH2 . ARG C 1 419 ? -65.331 27.384  71.878 1.00 45.49  ? 427 ARG C NH2 1 
ATOM   10491 N N   . GLY C 1 420 ? -59.600 32.039  70.052 1.00 101.77 ? 428 GLY C N   1 
ATOM   10492 C CA  . GLY C 1 420 ? -58.586 32.106  69.015 1.00 117.19 ? 428 GLY C CA  1 
ATOM   10493 C C   . GLY C 1 420 ? -57.179 32.354  69.577 1.00 95.07  ? 428 GLY C C   1 
ATOM   10494 O O   . GLY C 1 420 ? -56.228 31.690  69.189 1.00 79.14  ? 428 GLY C O   1 
ATOM   10495 N N   . ILE C 1 421 ? -57.024 33.330  70.477 1.00 67.99  ? 429 ILE C N   1 
ATOM   10496 C CA  . ILE C 1 421 ? -55.744 33.685  71.070 1.00 77.61  ? 429 ILE C CA  1 
ATOM   10497 C C   . ILE C 1 421 ? -55.171 32.525  71.883 1.00 87.21  ? 429 ILE C C   1 
ATOM   10498 O O   . ILE C 1 421 ? -53.954 32.322  71.903 1.00 87.67  ? 429 ILE C O   1 
ATOM   10499 C CB  . ILE C 1 421 ? -55.883 34.985  71.894 1.00 67.30  ? 429 ILE C CB  1 
ATOM   10500 C CG1 . ILE C 1 421 ? -56.373 36.132  70.986 1.00 77.76  ? 429 ILE C CG1 1 
ATOM   10501 C CG2 . ILE C 1 421 ? -54.596 35.332  72.666 1.00 44.34  ? 429 ILE C CG2 1 
ATOM   10502 C CD1 . ILE C 1 421 ? -55.535 36.376  69.738 1.00 70.94  ? 429 ILE C CD1 1 
ATOM   10503 N N   . GLU C 1 422 ? -56.050 31.796  72.579 1.00 72.66  ? 430 GLU C N   1 
ATOM   10504 C CA  . GLU C 1 422 ? -55.635 30.673  73.402 1.00 82.99  ? 430 GLU C CA  1 
ATOM   10505 C C   . GLU C 1 422 ? -55.007 29.629  72.474 1.00 97.16  ? 430 GLU C C   1 
ATOM   10506 O O   . GLU C 1 422 ? -53.915 29.111  72.769 1.00 103.76 ? 430 GLU C O   1 
ATOM   10507 C CB  . GLU C 1 422 ? -56.743 30.170  74.331 1.00 79.02  ? 430 GLU C CB  1 
ATOM   10508 C CG  . GLU C 1 422 ? -57.127 31.147  75.442 1.00 103.09 ? 430 GLU C CG  1 
ATOM   10509 C CD  . GLU C 1 422 ? -58.151 30.577  76.439 1.00 104.63 ? 430 GLU C CD  1 
ATOM   10510 O OE1 . GLU C 1 422 ? -58.966 29.825  75.840 1.00 107.53 ? 430 GLU C OE1 1 
ATOM   10511 O OE2 . GLU C 1 422 ? -58.237 30.832  77.707 1.00 62.09  ? 430 GLU C OE2 1 
ATOM   10512 N N   . LEU C 1 423 ? -55.683 29.369  71.342 1.00 70.06  ? 431 LEU C N   1 
ATOM   10513 C CA  . LEU C 1 423 ? -55.186 28.406  70.366 1.00 89.59  ? 431 LEU C CA  1 
ATOM   10514 C C   . LEU C 1 423 ? -53.825 28.865  69.822 1.00 107.75 ? 431 LEU C C   1 
ATOM   10515 O O   . LEU C 1 423 ? -52.882 28.079  69.651 1.00 84.66  ? 431 LEU C O   1 
ATOM   10516 C CB  . LEU C 1 423 ? -56.220 28.245  69.262 1.00 82.34  ? 431 LEU C CB  1 
ATOM   10517 C CG  . LEU C 1 423 ? -57.211 27.101  69.451 1.00 78.06  ? 431 LEU C CG  1 
ATOM   10518 C CD1 . LEU C 1 423 ? -58.098 26.983  68.226 1.00 84.27  ? 431 LEU C CD1 1 
ATOM   10519 C CD2 . LEU C 1 423 ? -56.438 25.803  69.622 1.00 91.69  ? 431 LEU C CD2 1 
ATOM   10520 N N   . THR C 1 424 ? -53.748 30.168  69.545 1.00 102.47 ? 432 THR C N   1 
ATOM   10521 C CA  . THR C 1 424 ? -52.511 30.781  69.100 1.00 103.81 ? 432 THR C CA  1 
ATOM   10522 C C   . THR C 1 424 ? -51.393 30.470  70.088 1.00 97.66  ? 432 THR C C   1 
ATOM   10523 O O   . THR C 1 424 ? -50.281 30.091  69.694 1.00 69.11  ? 432 THR C O   1 
ATOM   10524 C CB  . THR C 1 424 ? -52.745 32.281  68.941 1.00 103.64 ? 432 THR C CB  1 
ATOM   10525 O OG1 . THR C 1 424 ? -53.776 32.075  67.984 1.00 101.37 ? 432 THR C OG1 1 
ATOM   10526 C CG2 . THR C 1 424 ? -51.564 33.057  68.382 1.00 99.88  ? 432 THR C CG2 1 
ATOM   10527 N N   . LEU C 1 425 ? -51.678 30.670  71.381 1.00 81.51  ? 433 LEU C N   1 
ATOM   10528 C CA  . LEU C 1 425 ? -50.688 30.489  72.423 1.00 93.59  ? 433 LEU C CA  1 
ATOM   10529 C C   . LEU C 1 425 ? -50.255 29.027  72.510 1.00 103.40 ? 433 LEU C C   1 
ATOM   10530 O O   . LEU C 1 425 ? -49.060 28.745  72.709 1.00 89.96  ? 433 LEU C O   1 
ATOM   10531 C CB  . LEU C 1 425 ? -51.351 31.018  73.685 1.00 68.45  ? 433 LEU C CB  1 
ATOM   10532 C CG  . LEU C 1 425 ? -51.104 32.510  73.883 1.00 68.33  ? 433 LEU C CG  1 
ATOM   10533 C CD1 . LEU C 1 425 ? -52.136 33.223  74.722 1.00 46.84  ? 433 LEU C CD1 1 
ATOM   10534 C CD2 . LEU C 1 425 ? -49.709 32.667  74.471 1.00 67.20  ? 433 LEU C CD2 1 
ATOM   10535 N N   . GLN C 1 426 ? -51.242 28.126  72.370 1.00 74.22  ? 434 GLN C N   1 
ATOM   10536 C CA  . GLN C 1 426 ? -50.971 26.699  72.359 1.00 89.00  ? 434 GLN C CA  1 
ATOM   10537 C C   . GLN C 1 426 ? -49.933 26.405  71.288 1.00 83.58  ? 434 GLN C C   1 
ATOM   10538 O O   . GLN C 1 426 ? -48.812 25.984  71.582 1.00 66.83  ? 434 GLN C O   1 
ATOM   10539 C CB  . GLN C 1 426 ? -52.229 25.895  72.073 1.00 77.71  ? 434 GLN C CB  1 
ATOM   10540 C CG  . GLN C 1 426 ? -53.233 25.915  73.204 1.00 87.09  ? 434 GLN C CG  1 
ATOM   10541 C CD  . GLN C 1 426 ? -54.453 25.136  72.794 1.00 111.50 ? 434 GLN C CD  1 
ATOM   10542 O OE1 . GLN C 1 426 ? -54.322 24.003  72.333 1.00 109.24 ? 434 GLN C OE1 1 
ATOM   10543 N NE2 . GLN C 1 426 ? -55.634 25.731  72.899 1.00 147.97 ? 434 GLN C NE2 1 
ATOM   10544 N N   . ILE C 1 427 ? -50.284 26.747  70.053 1.00 71.72  ? 435 ILE C N   1 
ATOM   10545 C CA  . ILE C 1 427 ? -49.377 26.486  68.954 1.00 73.59  ? 435 ILE C CA  1 
ATOM   10546 C C   . ILE C 1 427 ? -47.986 27.101  69.181 1.00 81.75  ? 435 ILE C C   1 
ATOM   10547 O O   . ILE C 1 427 ? -46.990 26.443  68.945 1.00 88.68  ? 435 ILE C O   1 
ATOM   10548 C CB  . ILE C 1 427 ? -50.063 26.962  67.679 1.00 74.06  ? 435 ILE C CB  1 
ATOM   10549 C CG1 . ILE C 1 427 ? -51.412 26.222  67.597 1.00 85.14  ? 435 ILE C CG1 1 
ATOM   10550 C CG2 . ILE C 1 427 ? -49.175 26.765  66.447 1.00 78.52  ? 435 ILE C CG2 1 
ATOM   10551 C CD1 . ILE C 1 427 ? -52.383 26.712  66.539 1.00 131.19 ? 435 ILE C CD1 1 
ATOM   10552 N N   . GLN C 1 428 ? -47.921 28.364  69.611 1.00 78.03  ? 436 GLN C N   1 
ATOM   10553 C CA  . GLN C 1 428 ? -46.679 29.064  69.903 1.00 102.34 ? 436 GLN C CA  1 
ATOM   10554 C C   . GLN C 1 428 ? -45.809 28.301  70.903 1.00 112.71 ? 436 GLN C C   1 
ATOM   10555 O O   . GLN C 1 428 ? -44.635 28.084  70.648 1.00 124.65 ? 436 GLN C O   1 
ATOM   10556 C CB  . GLN C 1 428 ? -47.089 30.463  70.358 1.00 107.02 ? 436 GLN C CB  1 
ATOM   10557 C CG  . GLN C 1 428 ? -45.965 31.392  70.781 1.00 93.51  ? 436 GLN C CG  1 
ATOM   10558 C CD  . GLN C 1 428 ? -46.403 32.823  70.545 1.00 102.18 ? 436 GLN C CD  1 
ATOM   10559 O OE1 . GLN C 1 428 ? -47.521 33.103  70.109 1.00 121.24 ? 436 GLN C OE1 1 
ATOM   10560 N NE2 . GLN C 1 428 ? -45.521 33.756  70.805 1.00 100.93 ? 436 GLN C NE2 1 
ATOM   10561 N N   . SER C 1 429 ? -46.398 27.823  71.999 1.00 108.80 ? 437 SER C N   1 
ATOM   10562 C CA  . SER C 1 429 ? -45.652 27.102  73.020 1.00 112.66 ? 437 SER C CA  1 
ATOM   10563 C C   . SER C 1 429 ? -45.332 25.678  72.576 1.00 93.82  ? 437 SER C C   1 
ATOM   10564 O O   . SER C 1 429 ? -44.352 25.127  73.039 1.00 112.51 ? 437 SER C O   1 
ATOM   10565 C CB  . SER C 1 429 ? -46.351 27.110  74.343 1.00 116.57 ? 437 SER C CB  1 
ATOM   10566 O OG  . SER C 1 429 ? -47.588 26.424  74.208 1.00 171.13 ? 437 SER C OG  1 
ATOM   10567 N N   . ASP C 1 430 ? -46.113 25.104  71.653 1.00 83.59  ? 438 ASP C N   1 
ATOM   10568 C CA  . ASP C 1 430 ? -45.849 23.836  70.990 1.00 105.20 ? 438 ASP C CA  1 
ATOM   10569 C C   . ASP C 1 430 ? -44.724 23.966  69.958 1.00 127.14 ? 438 ASP C C   1 
ATOM   10570 O O   . ASP C 1 430 ? -44.153 22.963  69.559 1.00 131.42 ? 438 ASP C O   1 
ATOM   10571 C CB  . ASP C 1 430 ? -47.128 23.310  70.333 1.00 86.94  ? 438 ASP C CB  1 
ATOM   10572 C CG  . ASP C 1 430 ? -47.746 22.029  70.891 1.00 97.94  ? 438 ASP C CG  1 
ATOM   10573 O OD1 . ASP C 1 430 ? -47.837 21.871  72.165 1.00 76.96  ? 438 ASP C OD1 1 
ATOM   10574 O OD2 . ASP C 1 430 ? -48.123 21.200  70.022 1.00 81.69  ? 438 ASP C OD2 1 
ATOM   10575 N N   . THR C 1 431 ? -44.467 25.206  69.503 1.00 148.50 ? 439 THR C N   1 
ATOM   10576 C CA  . THR C 1 431 ? -43.533 25.628  68.481 1.00 103.29 ? 439 THR C CA  1 
ATOM   10577 C C   . THR C 1 431 ? -42.222 26.106  69.104 1.00 109.49 ? 439 THR C C   1 
ATOM   10578 O O   . THR C 1 431 ? -41.216 26.177  68.407 1.00 107.33 ? 439 THR C O   1 
ATOM   10579 C CB  . THR C 1 431 ? -44.243 26.746  67.709 1.00 106.96 ? 439 THR C CB  1 
ATOM   10580 O OG1 . THR C 1 431 ? -45.027 25.843  66.934 1.00 74.67  ? 439 THR C OG1 1 
ATOM   10581 C CG2 . THR C 1 431 ? -43.321 27.674  66.931 1.00 129.26 ? 439 THR C CG2 1 
ATOM   10582 N N   . GLY C 1 432 ? -42.233 26.427  70.410 1.00 107.31 ? 440 GLY C N   1 
ATOM   10583 C CA  . GLY C 1 432 ? -41.035 26.794  71.156 1.00 123.42 ? 440 GLY C CA  1 
ATOM   10584 C C   . GLY C 1 432 ? -40.595 28.240  70.890 1.00 147.83 ? 440 GLY C C   1 
ATOM   10585 O O   . GLY C 1 432 ? -41.372 29.034  70.346 1.00 134.99 ? 440 GLY C O   1 
ATOM   10586 N N   . VAL C 1 433 ? -39.331 28.538  71.228 1.00 154.79 ? 441 VAL C N   1 
ATOM   10587 C CA  . VAL C 1 433 ? -38.832 29.894  71.467 1.00 131.86 ? 441 VAL C CA  1 
ATOM   10588 C C   . VAL C 1 433 ? -38.909 30.716  70.168 1.00 135.52 ? 441 VAL C C   1 
ATOM   10589 O O   . VAL C 1 433 ? -39.991 31.195  69.821 1.00 124.20 ? 441 VAL C O   1 
ATOM   10590 C CB  . VAL C 1 433 ? -37.498 30.003  72.264 1.00 111.58 ? 441 VAL C CB  1 
ATOM   10591 C CG1 . VAL C 1 433 ? -36.916 31.403  72.308 1.00 92.47  ? 441 VAL C CG1 1 
ATOM   10592 C CG2 . VAL C 1 433 ? -37.592 29.531  73.718 1.00 123.71 ? 441 VAL C CG2 1 
ATOM   10593 N N   . ALA C 1 434 ? -37.799 30.870  69.416 1.00 131.93 ? 442 ALA C N   1 
ATOM   10594 C CA  . ALA C 1 434 ? -37.738 31.785  68.275 1.00 134.48 ? 442 ALA C CA  1 
ATOM   10595 C C   . ALA C 1 434 ? -37.685 31.007  66.944 1.00 123.52 ? 442 ALA C C   1 
ATOM   10596 O O   . ALA C 1 434 ? -36.628 30.536  66.533 1.00 145.38 ? 442 ALA C O   1 
ATOM   10597 C CB  . ALA C 1 434 ? -36.537 32.711  68.400 1.00 30.00  ? 442 ALA C CB  1 
ATOM   10598 N N   . ALA C 1 435 ? -38.810 30.944  66.216 1.00 86.16  ? 443 ALA C N   1 
ATOM   10599 C CA  . ALA C 1 435 ? -39.097 29.881  65.258 1.00 90.11  ? 443 ALA C CA  1 
ATOM   10600 C C   . ALA C 1 435 ? -39.993 30.403  64.130 1.00 92.22  ? 443 ALA C C   1 
ATOM   10601 O O   . ALA C 1 435 ? -41.026 31.024  64.397 1.00 97.74  ? 443 ALA C O   1 
ATOM   10602 C CB  . ALA C 1 435 ? -39.732 28.715  66.016 1.00 89.39  ? 443 ALA C CB  1 
ATOM   10603 N N   . THR C 1 436 ? -39.623 30.110  62.867 1.00 89.39  ? 444 THR C N   1 
ATOM   10604 C CA  . THR C 1 436 ? -40.245 30.739  61.704 1.00 92.04  ? 444 THR C CA  1 
ATOM   10605 C C   . THR C 1 436 ? -41.773 30.708  61.858 1.00 102.06 ? 444 THR C C   1 
ATOM   10606 O O   . THR C 1 436 ? -42.394 29.651  62.103 1.00 98.51  ? 444 THR C O   1 
ATOM   10607 C CB  . THR C 1 436 ? -39.828 30.123  60.355 1.00 103.76 ? 444 THR C CB  1 
ATOM   10608 O OG1 . THR C 1 436 ? -40.238 28.764  60.338 1.00 109.29 ? 444 THR C OG1 1 
ATOM   10609 C CG2 . THR C 1 436 ? -38.344 30.009  60.076 1.00 95.99  ? 444 THR C CG2 1 
ATOM   10610 N N   . LEU C 1 437 ? -42.391 31.861  61.577 1.00 101.60 ? 445 LEU C N   1 
ATOM   10611 C CA  . LEU C 1 437 ? -43.834 31.936  61.421 1.00 104.00 ? 445 LEU C CA  1 
ATOM   10612 C C   . LEU C 1 437 ? -44.304 30.828  60.470 1.00 114.12 ? 445 LEU C C   1 
ATOM   10613 O O   . LEU C 1 437 ? -45.498 30.496  60.440 1.00 111.20 ? 445 LEU C O   1 
ATOM   10614 C CB  . LEU C 1 437 ? -44.195 33.335  60.896 1.00 85.10  ? 445 LEU C CB  1 
ATOM   10615 C CG  . LEU C 1 437 ? -45.670 33.538  60.511 1.00 69.51  ? 445 LEU C CG  1 
ATOM   10616 C CD1 . LEU C 1 437 ? -46.386 33.690  61.786 1.00 72.40  ? 445 LEU C CD1 1 
ATOM   10617 C CD2 . LEU C 1 437 ? -46.041 34.703  59.625 1.00 88.44  ? 445 LEU C CD2 1 
ATOM   10618 N N   . LYS C 1 438 ? -43.322 30.281  59.710 1.00 87.23  ? 446 LYS C N   1 
ATOM   10619 C CA  . LYS C 1 438 ? -43.498 29.230  58.720 1.00 79.89  ? 446 LYS C CA  1 
ATOM   10620 C C   . LYS C 1 438 ? -43.930 27.979  59.475 1.00 91.56  ? 446 LYS C C   1 
ATOM   10621 O O   . LYS C 1 438 ? -45.018 27.461  59.221 1.00 88.61  ? 446 LYS C O   1 
ATOM   10622 C CB  . LYS C 1 438 ? -42.233 29.170  57.855 1.00 87.67  ? 446 LYS C CB  1 
ATOM   10623 C CG  . LYS C 1 438 ? -42.126 28.022  56.853 1.00 104.65 ? 446 LYS C CG  1 
ATOM   10624 C CD  . LYS C 1 438 ? -40.703 27.572  56.508 1.00 110.52 ? 446 LYS C CD  1 
ATOM   10625 C CE  . LYS C 1 438 ? -40.749 26.613  55.349 1.00 109.02 ? 446 LYS C CE  1 
ATOM   10626 N NZ  . LYS C 1 438 ? -39.417 26.197  54.907 1.00 150.85 ? 446 LYS C NZ  1 
ATOM   10627 N N   . GLU C 1 439 ? -43.076 27.547  60.419 1.00 110.79 ? 447 GLU C N   1 
ATOM   10628 C CA  . GLU C 1 439 ? -43.321 26.418  61.306 1.00 105.32 ? 447 GLU C CA  1 
ATOM   10629 C C   . GLU C 1 439 ? -44.737 26.571  61.852 1.00 114.28 ? 447 GLU C C   1 
ATOM   10630 O O   . GLU C 1 439 ? -45.598 25.739  61.506 1.00 87.30  ? 447 GLU C O   1 
ATOM   10631 C CB  . GLU C 1 439 ? -42.226 26.340  62.374 1.00 93.30  ? 447 GLU C CB  1 
ATOM   10632 C CG  . GLU C 1 439 ? -40.912 25.755  61.875 1.00 108.53 ? 447 GLU C CG  1 
ATOM   10633 C CD  . GLU C 1 439 ? -39.688 26.251  62.638 1.00 125.82 ? 447 GLU C CD  1 
ATOM   10634 O OE1 . GLU C 1 439 ? -39.058 25.504  63.418 1.00 149.42 ? 447 GLU C OE1 1 
ATOM   10635 O OE2 . GLU C 1 439 ? -39.336 27.424  62.425 1.00 137.14 ? 447 GLU C OE2 1 
ATOM   10636 N N   . PHE C 1 440 ? -44.985 27.707  62.545 1.00 89.65  ? 448 PHE C N   1 
ATOM   10637 C CA  . PHE C 1 440 ? -46.279 28.011  63.149 1.00 110.39 ? 448 PHE C CA  1 
ATOM   10638 C C   . PHE C 1 440 ? -47.475 27.726  62.214 1.00 122.01 ? 448 PHE C C   1 
ATOM   10639 O O   . PHE C 1 440 ? -48.414 27.034  62.615 1.00 97.11  ? 448 PHE C O   1 
ATOM   10640 C CB  . PHE C 1 440 ? -46.288 29.459  63.660 1.00 126.05 ? 448 PHE C CB  1 
ATOM   10641 C CG  . PHE C 1 440 ? -47.557 29.830  64.428 1.00 122.06 ? 448 PHE C CG  1 
ATOM   10642 C CD1 . PHE C 1 440 ? -48.740 30.201  63.786 1.00 125.22 ? 448 PHE C CD1 1 
ATOM   10643 C CD2 . PHE C 1 440 ? -47.535 29.903  65.812 1.00 127.48 ? 448 PHE C CD2 1 
ATOM   10644 C CE1 . PHE C 1 440 ? -49.895 30.461  64.500 1.00 126.26 ? 448 PHE C CE1 1 
ATOM   10645 C CE2 . PHE C 1 440 ? -48.678 30.239  66.531 1.00 110.58 ? 448 PHE C CE2 1 
ATOM   10646 C CZ  . PHE C 1 440 ? -49.847 30.552  65.868 1.00 98.17  ? 448 PHE C CZ  1 
ATOM   10647 N N   . LYS C 1 441 ? -47.456 28.261  60.970 1.00 106.90 ? 449 LYS C N   1 
ATOM   10648 C CA  . LYS C 1 441 ? -48.488 27.987  59.979 1.00 104.62 ? 449 LYS C CA  1 
ATOM   10649 C C   . LYS C 1 441 ? -48.588 26.475  59.735 1.00 106.33 ? 449 LYS C C   1 
ATOM   10650 O O   . LYS C 1 441 ? -49.683 25.944  59.473 1.00 94.74  ? 449 LYS C O   1 
ATOM   10651 C CB  . LYS C 1 441 ? -48.157 28.721  58.673 1.00 109.19 ? 449 LYS C CB  1 
ATOM   10652 C CG  . LYS C 1 441 ? -48.251 30.235  58.646 1.00 107.20 ? 449 LYS C CG  1 
ATOM   10653 C CD  . LYS C 1 441 ? -47.846 30.890  57.322 1.00 99.99  ? 449 LYS C CD  1 
ATOM   10654 C CE  . LYS C 1 441 ? -46.371 31.286  57.297 1.00 90.46  ? 449 LYS C CE  1 
ATOM   10655 N NZ  . LYS C 1 441 ? -45.555 31.523  56.084 1.00 50.20  ? 449 LYS C NZ  1 
ATOM   10656 N N   . GLU C 1 442 ? -47.441 25.791  59.874 1.00 82.72  ? 450 GLU C N   1 
ATOM   10657 C CA  . GLU C 1 442 ? -47.395 24.367  59.595 1.00 99.21  ? 450 GLU C CA  1 
ATOM   10658 C C   . GLU C 1 442 ? -48.123 23.596  60.682 1.00 95.57  ? 450 GLU C C   1 
ATOM   10659 O O   . GLU C 1 442 ? -48.969 22.747  60.391 1.00 91.89  ? 450 GLU C O   1 
ATOM   10660 C CB  . GLU C 1 442 ? -45.974 23.871  59.341 1.00 110.02 ? 450 GLU C CB  1 
ATOM   10661 C CG  . GLU C 1 442 ? -45.538 24.286  57.942 1.00 141.22 ? 450 GLU C CG  1 
ATOM   10662 C CD  . GLU C 1 442 ? -44.087 24.032  57.642 1.00 144.25 ? 450 GLU C CD  1 
ATOM   10663 O OE1 . GLU C 1 442 ? -43.336 23.640  58.576 1.00 141.39 ? 450 GLU C OE1 1 
ATOM   10664 O OE2 . GLU C 1 442 ? -43.753 24.254  56.452 1.00 115.85 ? 450 GLU C OE2 1 
ATOM   10665 N N   . ARG C 1 443 ? -47.765 23.928  61.928 1.00 69.87  ? 451 ARG C N   1 
ATOM   10666 C CA  . ARG C 1 443 ? -48.344 23.300  63.100 1.00 86.73  ? 451 ARG C CA  1 
ATOM   10667 C C   . ARG C 1 443 ? -49.857 23.540  63.123 1.00 94.77  ? 451 ARG C C   1 
ATOM   10668 O O   . ARG C 1 443 ? -50.614 22.647  63.529 1.00 89.97  ? 451 ARG C O   1 
ATOM   10669 C CB  . ARG C 1 443 ? -47.606 23.926  64.290 1.00 77.07  ? 451 ARG C CB  1 
ATOM   10670 C CG  . ARG C 1 443 ? -47.899 23.265  65.622 1.00 86.95  ? 451 ARG C CG  1 
ATOM   10671 C CD  . ARG C 1 443 ? -47.761 21.755  65.502 1.00 125.78 ? 451 ARG C CD  1 
ATOM   10672 N NE  . ARG C 1 443 ? -46.346 21.396  65.648 1.00 131.41 ? 451 ARG C NE  1 
ATOM   10673 C CZ  . ARG C 1 443 ? -45.592 21.679  66.716 1.00 143.32 ? 451 ARG C CZ  1 
ATOM   10674 N NH1 . ARG C 1 443 ? -46.118 22.177  67.827 1.00 118.07 ? 451 ARG C NH1 1 
ATOM   10675 N NH2 . ARG C 1 443 ? -44.302 21.415  66.667 1.00 155.56 ? 451 ARG C NH2 1 
ATOM   10676 N N   . LEU C 1 444 ? -50.264 24.743  62.666 1.00 109.91 ? 452 LEU C N   1 
ATOM   10677 C CA  . LEU C 1 444 ? -51.655 25.152  62.569 1.00 106.76 ? 452 LEU C CA  1 
ATOM   10678 C C   . LEU C 1 444 ? -52.435 24.166  61.693 1.00 86.25  ? 452 LEU C C   1 
ATOM   10679 O O   . LEU C 1 444 ? -53.554 23.794  62.057 1.00 71.38  ? 452 LEU C O   1 
ATOM   10680 C CB  . LEU C 1 444 ? -51.815 26.608  62.116 1.00 107.30 ? 452 LEU C CB  1 
ATOM   10681 C CG  . LEU C 1 444 ? -53.252 27.066  61.816 1.00 93.87  ? 452 LEU C CG  1 
ATOM   10682 C CD1 . LEU C 1 444 ? -54.004 27.153  63.100 1.00 92.18  ? 452 LEU C CD1 1 
ATOM   10683 C CD2 . LEU C 1 444 ? -53.524 28.269  60.962 1.00 103.54 ? 452 LEU C CD2 1 
ATOM   10684 N N   . ALA C 1 445 ? -51.838 23.749  60.566 1.00 91.54  ? 453 ALA C N   1 
ATOM   10685 C CA  . ALA C 1 445 ? -52.538 22.898  59.607 1.00 106.58 ? 453 ALA C CA  1 
ATOM   10686 C C   . ALA C 1 445 ? -52.465 21.445  60.049 1.00 94.56  ? 453 ALA C C   1 
ATOM   10687 O O   . ALA C 1 445 ? -53.364 20.667  59.698 1.00 66.96  ? 453 ALA C O   1 
ATOM   10688 C CB  . ALA C 1 445 ? -52.113 23.088  58.164 1.00 93.42  ? 453 ALA C CB  1 
ATOM   10689 N N   . GLY C 1 446 ? -51.446 21.109  60.859 1.00 96.71  ? 454 GLY C N   1 
ATOM   10690 C CA  . GLY C 1 446 ? -51.280 19.791  61.471 1.00 107.59 ? 454 GLY C CA  1 
ATOM   10691 C C   . GLY C 1 446 ? -52.575 19.257  62.083 1.00 102.29 ? 454 GLY C C   1 
ATOM   10692 O O   . GLY C 1 446 ? -53.380 20.025  62.619 1.00 93.77  ? 454 GLY C O   1 
ATOM   10693 N N   . ASP C 1 447 ? -52.768 17.938  61.928 1.00 110.88 ? 455 ASP C N   1 
ATOM   10694 C CA  . ASP C 1 447 ? -53.910 17.158  62.396 1.00 118.49 ? 455 ASP C CA  1 
ATOM   10695 C C   . ASP C 1 447 ? -54.357 17.524  63.809 1.00 129.09 ? 455 ASP C C   1 
ATOM   10696 O O   . ASP C 1 447 ? -55.551 17.722  64.074 1.00 150.34 ? 455 ASP C O   1 
ATOM   10697 C CB  . ASP C 1 447 ? -53.545 15.696  62.614 1.00 103.96 ? 455 ASP C CB  1 
ATOM   10698 C CG  . ASP C 1 447 ? -53.894 14.748  61.475 1.00 120.55 ? 455 ASP C CG  1 
ATOM   10699 O OD1 . ASP C 1 447 ? -53.391 14.968  60.338 1.00 96.97  ? 455 ASP C OD1 1 
ATOM   10700 O OD2 . ASP C 1 447 ? -54.673 13.798  61.741 1.00 110.28 ? 455 ASP C OD2 1 
ATOM   10701 N N   . LYS C 1 448 ? -53.391 17.505  64.740 1.00 126.76 ? 456 LYS C N   1 
ATOM   10702 C CA  . LYS C 1 448 ? -53.656 17.757  66.153 1.00 126.31 ? 456 LYS C CA  1 
ATOM   10703 C C   . LYS C 1 448 ? -54.617 18.953  66.275 1.00 127.55 ? 456 LYS C C   1 
ATOM   10704 O O   . LYS C 1 448 ? -55.766 18.856  66.739 1.00 109.51 ? 456 LYS C O   1 
ATOM   10705 C CB  . LYS C 1 448 ? -52.246 17.945  66.746 1.00 104.06 ? 456 LYS C CB  1 
ATOM   10706 C CG  . LYS C 1 448 ? -52.024 18.180  68.232 1.00 132.15 ? 456 LYS C CG  1 
ATOM   10707 C CD  . LYS C 1 448 ? -50.761 19.032  68.403 1.00 134.94 ? 456 LYS C CD  1 
ATOM   10708 C CE  . LYS C 1 448 ? -50.190 19.133  69.786 1.00 119.08 ? 456 LYS C CE  1 
ATOM   10709 N NZ  . LYS C 1 448 ? -51.054 19.773  70.786 1.00 90.85  ? 456 LYS C NZ  1 
ATOM   10710 N N   . TYR C 1 449 ? -54.145 20.077  65.733 1.00 138.67 ? 457 TYR C N   1 
ATOM   10711 C CA  . TYR C 1 449 ? -54.773 21.343  66.052 1.00 121.64 ? 457 TYR C CA  1 
ATOM   10712 C C   . TYR C 1 449 ? -55.974 21.561  65.150 1.00 123.30 ? 457 TYR C C   1 
ATOM   10713 O O   . TYR C 1 449 ? -56.946 22.123  65.618 1.00 142.49 ? 457 TYR C O   1 
ATOM   10714 C CB  . TYR C 1 449 ? -53.752 22.468  65.987 1.00 103.27 ? 457 TYR C CB  1 
ATOM   10715 C CG  . TYR C 1 449 ? -52.913 22.656  67.237 1.00 98.63  ? 457 TYR C CG  1 
ATOM   10716 C CD1 . TYR C 1 449 ? -53.385 23.399  68.317 1.00 84.00  ? 457 TYR C CD1 1 
ATOM   10717 C CD2 . TYR C 1 449 ? -51.625 22.129  67.308 1.00 105.92 ? 457 TYR C CD2 1 
ATOM   10718 C CE1 . TYR C 1 449 ? -52.577 23.667  69.416 1.00 73.53  ? 457 TYR C CE1 1 
ATOM   10719 C CE2 . TYR C 1 449 ? -50.826 22.351  68.419 1.00 104.18 ? 457 TYR C CE2 1 
ATOM   10720 C CZ  . TYR C 1 449 ? -51.301 23.134  69.463 1.00 90.44  ? 457 TYR C CZ  1 
ATOM   10721 O OH  . TYR C 1 449 ? -50.521 23.390  70.546 1.00 105.66 ? 457 TYR C OH  1 
ATOM   10722 N N   . GLN C 1 450 ? -55.893 21.109  63.897 1.00 126.75 ? 458 GLN C N   1 
ATOM   10723 C CA  . GLN C 1 450 ? -57.004 21.166  62.962 1.00 153.46 ? 458 GLN C CA  1 
ATOM   10724 C C   . GLN C 1 450 ? -58.320 20.702  63.580 1.00 150.19 ? 458 GLN C C   1 
ATOM   10725 O O   . GLN C 1 450 ? -59.382 21.233  63.258 1.00 150.06 ? 458 GLN C O   1 
ATOM   10726 C CB  . GLN C 1 450 ? -56.698 20.469  61.638 1.00 155.16 ? 458 GLN C CB  1 
ATOM   10727 C CG  . GLN C 1 450 ? -55.938 21.346  60.649 1.00 137.17 ? 458 GLN C CG  1 
ATOM   10728 C CD  . GLN C 1 450 ? -56.554 22.706  60.368 1.00 148.18 ? 458 GLN C CD  1 
ATOM   10729 O OE1 . GLN C 1 450 ? -56.031 23.742  60.802 1.00 145.72 ? 458 GLN C OE1 1 
ATOM   10730 N NE2 . GLN C 1 450 ? -57.659 22.707  59.640 1.00 177.93 ? 458 GLN C NE2 1 
ATOM   10731 N N   . ALA C 1 451 ? -58.230 19.715  64.474 1.00 134.44 ? 459 ALA C N   1 
ATOM   10732 C CA  . ALA C 1 451 ? -59.392 19.210  65.188 1.00 129.16 ? 459 ALA C CA  1 
ATOM   10733 C C   . ALA C 1 451 ? -60.057 20.306  66.047 1.00 121.50 ? 459 ALA C C   1 
ATOM   10734 O O   . ALA C 1 451 ? -61.255 20.599  65.906 1.00 157.50 ? 459 ALA C O   1 
ATOM   10735 C CB  . ALA C 1 451 ? -58.983 17.965  65.961 1.00 103.43 ? 459 ALA C CB  1 
ATOM   10736 N N   . ALA C 1 452 ? -59.251 20.946  66.904 1.00 90.66  ? 460 ALA C N   1 
ATOM   10737 C CA  . ALA C 1 452 ? -59.675 22.033  67.784 1.00 112.89 ? 460 ALA C CA  1 
ATOM   10738 C C   . ALA C 1 452 ? -60.162 23.222  66.963 1.00 137.49 ? 460 ALA C C   1 
ATOM   10739 O O   . ALA C 1 452 ? -61.227 23.787  67.231 1.00 122.40 ? 460 ALA C O   1 
ATOM   10740 C CB  . ALA C 1 452 ? -58.529 22.466  68.683 1.00 105.88 ? 460 ALA C CB  1 
ATOM   10741 N N   . VAL C 1 453 ? -59.385 23.574  65.928 1.00 145.06 ? 461 VAL C N   1 
ATOM   10742 C CA  . VAL C 1 453 ? -59.681 24.687  65.036 1.00 116.36 ? 461 VAL C CA  1 
ATOM   10743 C C   . VAL C 1 453 ? -61.068 24.468  64.436 1.00 135.43 ? 461 VAL C C   1 
ATOM   10744 O O   . VAL C 1 453 ? -61.873 25.400  64.440 1.00 122.18 ? 461 VAL C O   1 
ATOM   10745 C CB  . VAL C 1 453 ? -58.635 24.822  63.908 1.00 123.21 ? 461 VAL C CB  1 
ATOM   10746 C CG1 . VAL C 1 453 ? -59.095 25.709  62.749 1.00 124.84 ? 461 VAL C CG1 1 
ATOM   10747 C CG2 . VAL C 1 453 ? -57.294 25.297  64.416 1.00 124.15 ? 461 VAL C CG2 1 
ATOM   10748 N N   . GLN C 1 454 ? -61.337 23.223  63.997 1.00 142.39 ? 462 GLN C N   1 
ATOM   10749 C CA  . GLN C 1 454 ? -62.591 22.942  63.318 1.00 142.95 ? 462 GLN C CA  1 
ATOM   10750 C C   . GLN C 1 454 ? -63.750 23.074  64.308 1.00 157.00 ? 462 GLN C C   1 
ATOM   10751 O O   . GLN C 1 454 ? -64.808 23.604  63.967 1.00 142.24 ? 462 GLN C O   1 
ATOM   10752 C CB  . GLN C 1 454 ? -62.677 21.767  62.340 1.00 113.69 ? 462 GLN C CB  1 
ATOM   10753 C CG  . GLN C 1 454 ? -63.330 22.208  61.022 1.00 126.45 ? 462 GLN C CG  1 
ATOM   10754 C CD  . GLN C 1 454 ? -64.080 21.172  60.195 1.00 138.74 ? 462 GLN C CD  1 
ATOM   10755 O OE1 . GLN C 1 454 ? -64.325 20.035  60.623 1.00 136.70 ? 462 GLN C OE1 1 
ATOM   10756 N NE2 . GLN C 1 454 ? -64.489 21.579  58.992 1.00 92.58  ? 462 GLN C NE2 1 
ATOM   10757 N N   . ALA C 1 455 ? -63.539 22.637  65.550 1.00 154.96 ? 463 ALA C N   1 
ATOM   10758 C CA  . ALA C 1 455 ? -64.547 22.802  66.584 1.00 148.56 ? 463 ALA C CA  1 
ATOM   10759 C C   . ALA C 1 455 ? -64.898 24.278  66.752 1.00 146.19 ? 463 ALA C C   1 
ATOM   10760 O O   . ALA C 1 455 ? -66.055 24.651  66.666 1.00 150.81 ? 463 ALA C O   1 
ATOM   10761 C CB  . ALA C 1 455 ? -64.082 22.172  67.872 1.00 171.68 ? 463 ALA C CB  1 
ATOM   10762 N N   . LEU C 1 456 ? -63.897 25.097  67.073 1.00 141.07 ? 464 LEU C N   1 
ATOM   10763 C CA  . LEU C 1 456 ? -64.128 26.511  67.322 1.00 121.10 ? 464 LEU C CA  1 
ATOM   10764 C C   . LEU C 1 456 ? -64.741 27.154  66.076 1.00 124.85 ? 464 LEU C C   1 
ATOM   10765 O O   . LEU C 1 456 ? -65.697 27.932  66.174 1.00 120.18 ? 464 LEU C O   1 
ATOM   10766 C CB  . LEU C 1 456 ? -62.820 27.168  67.755 1.00 96.63  ? 464 LEU C CB  1 
ATOM   10767 C CG  . LEU C 1 456 ? -62.867 28.676  68.009 1.00 89.04  ? 464 LEU C CG  1 
ATOM   10768 C CD1 . LEU C 1 456 ? -63.911 28.784  69.062 1.00 72.47  ? 464 LEU C CD1 1 
ATOM   10769 C CD2 . LEU C 1 456 ? -61.544 29.357  68.413 1.00 93.62  ? 464 LEU C CD2 1 
ATOM   10770 N N   . ARG C 1 457 ? -64.169 26.840  64.902 1.00 96.07  ? 465 ARG C N   1 
ATOM   10771 C CA  . ARG C 1 457 ? -64.634 27.409  63.646 1.00 113.61 ? 465 ARG C CA  1 
ATOM   10772 C C   . ARG C 1 457 ? -66.144 27.172  63.519 1.00 117.14 ? 465 ARG C C   1 
ATOM   10773 O O   . ARG C 1 457 ? -66.887 28.088  63.174 1.00 90.64  ? 465 ARG C O   1 
ATOM   10774 C CB  . ARG C 1 457 ? -63.863 26.812  62.460 1.00 111.33 ? 465 ARG C CB  1 
ATOM   10775 C CG  . ARG C 1 457 ? -64.325 27.310  61.093 1.00 70.95  ? 465 ARG C CG  1 
ATOM   10776 C CD  . ARG C 1 457 ? -63.490 26.656  59.991 1.00 102.66 ? 465 ARG C CD  1 
ATOM   10777 N NE  . ARG C 1 457 ? -64.053 25.311  59.851 1.00 145.46 ? 465 ARG C NE  1 
ATOM   10778 C CZ  . ARG C 1 457 ? -64.896 24.924  58.904 1.00 160.23 ? 465 ARG C CZ  1 
ATOM   10779 N NH1 . ARG C 1 457 ? -64.851 25.508  57.720 1.00 166.38 ? 465 ARG C NH1 1 
ATOM   10780 N NH2 . ARG C 1 457 ? -65.738 23.921  59.130 1.00 144.11 ? 465 ARG C NH2 1 
ATOM   10781 N N   . GLU C 1 458 ? -66.586 25.947  63.829 1.00 112.60 ? 466 GLU C N   1 
ATOM   10782 C CA  . GLU C 1 458 ? -67.984 25.569  63.702 1.00 121.63 ? 466 GLU C CA  1 
ATOM   10783 C C   . GLU C 1 458 ? -68.860 26.445  64.582 1.00 99.73  ? 466 GLU C C   1 
ATOM   10784 O O   . GLU C 1 458 ? -69.848 26.994  64.111 1.00 99.67  ? 466 GLU C O   1 
ATOM   10785 C CB  . GLU C 1 458 ? -68.205 24.074  63.903 1.00 112.20 ? 466 GLU C CB  1 
ATOM   10786 C CG  . GLU C 1 458 ? -67.901 23.332  62.603 1.00 136.61 ? 466 GLU C CG  1 
ATOM   10787 C CD  . GLU C 1 458 ? -68.712 22.086  62.313 1.00 145.26 ? 466 GLU C CD  1 
ATOM   10788 O OE1 . GLU C 1 458 ? -69.938 22.029  62.573 1.00 145.03 ? 466 GLU C OE1 1 
ATOM   10789 O OE2 . GLU C 1 458 ? -68.080 21.167  61.761 1.00 155.60 ? 466 GLU C OE2 1 
ATOM   10790 N N   . GLU C 1 459 ? -68.461 26.616  65.844 1.00 93.23  ? 467 GLU C N   1 
ATOM   10791 C CA  . GLU C 1 459 ? -69.183 27.445  66.812 1.00 97.36  ? 467 GLU C CA  1 
ATOM   10792 C C   . GLU C 1 459 ? -69.336 28.853  66.240 1.00 108.53 ? 467 GLU C C   1 
ATOM   10793 O O   . GLU C 1 459 ? -70.425 29.436  66.288 1.00 96.67  ? 467 GLU C O   1 
ATOM   10794 C CB  . GLU C 1 459 ? -68.404 27.481  68.133 1.00 85.00  ? 467 GLU C CB  1 
ATOM   10795 C CG  . GLU C 1 459 ? -69.143 27.959  69.375 1.00 100.51 ? 467 GLU C CG  1 
ATOM   10796 C CD  . GLU C 1 459 ? -68.260 27.801  70.613 1.00 115.65 ? 467 GLU C CD  1 
ATOM   10797 O OE1 . GLU C 1 459 ? -67.914 26.654  71.000 1.00 117.96 ? 467 GLU C OE1 1 
ATOM   10798 O OE2 . GLU C 1 459 ? -67.915 28.831  71.244 1.00 109.07 ? 467 GLU C OE2 1 
ATOM   10799 N N   . VAL C 1 460 ? -68.199 29.390  65.757 1.00 122.75 ? 468 VAL C N   1 
ATOM   10800 C CA  . VAL C 1 460 ? -68.119 30.727  65.199 1.00 109.01 ? 468 VAL C CA  1 
ATOM   10801 C C   . VAL C 1 460 ? -69.082 30.847  64.017 1.00 102.76 ? 468 VAL C C   1 
ATOM   10802 O O   . VAL C 1 460 ? -69.854 31.800  63.929 1.00 108.49 ? 468 VAL C O   1 
ATOM   10803 C CB  . VAL C 1 460 ? -66.665 31.038  64.800 1.00 106.94 ? 468 VAL C CB  1 
ATOM   10804 C CG1 . VAL C 1 460 ? -66.560 32.225  63.850 1.00 94.62  ? 468 VAL C CG1 1 
ATOM   10805 C CG2 . VAL C 1 460 ? -65.797 31.246  66.034 1.00 145.03 ? 468 VAL C CG2 1 
ATOM   10806 N N   . GLU C 1 461 ? -69.020 29.891  63.091 1.00 87.53  ? 469 GLU C N   1 
ATOM   10807 C CA  . GLU C 1 461 ? -69.857 29.957  61.897 1.00 92.56  ? 469 GLU C CA  1 
ATOM   10808 C C   . GLU C 1 461 ? -71.342 29.899  62.263 1.00 98.98  ? 469 GLU C C   1 
ATOM   10809 O O   . GLU C 1 461 ? -72.150 30.656  61.728 1.00 78.39  ? 469 GLU C O   1 
ATOM   10810 C CB  . GLU C 1 461 ? -69.470 28.930  60.830 1.00 99.20  ? 469 GLU C CB  1 
ATOM   10811 C CG  . GLU C 1 461 ? -68.063 29.117  60.276 1.00 93.00  ? 469 GLU C CG  1 
ATOM   10812 C CD  . GLU C 1 461 ? -67.674 28.141  59.198 1.00 95.20  ? 469 GLU C CD  1 
ATOM   10813 O OE1 . GLU C 1 461 ? -68.489 27.340  58.725 1.00 120.86 ? 469 GLU C OE1 1 
ATOM   10814 O OE2 . GLU C 1 461 ? -66.503 28.168  58.840 1.00 87.12  ? 469 GLU C OE2 1 
ATOM   10815 N N   . SER C 1 462 ? -71.725 28.981  63.159 1.00 105.41 ? 470 SER C N   1 
ATOM   10816 C CA  . SER C 1 462 ? -73.117 28.872  63.574 1.00 100.51 ? 470 SER C CA  1 
ATOM   10817 C C   . SER C 1 462 ? -73.593 30.189  64.183 1.00 105.61 ? 470 SER C C   1 
ATOM   10818 O O   . SER C 1 462 ? -74.693 30.608  63.845 1.00 113.66 ? 470 SER C O   1 
ATOM   10819 C CB  . SER C 1 462 ? -73.353 27.708  64.484 1.00 76.09  ? 470 SER C CB  1 
ATOM   10820 O OG  . SER C 1 462 ? -72.214 27.618  65.337 1.00 123.38 ? 470 SER C OG  1 
ATOM   10821 N N   . PHE C 1 463 ? -72.772 30.850  65.017 1.00 105.86 ? 471 PHE C N   1 
ATOM   10822 C CA  . PHE C 1 463 ? -73.139 32.149  65.583 1.00 134.02 ? 471 PHE C CA  1 
ATOM   10823 C C   . PHE C 1 463 ? -73.376 33.212  64.498 1.00 136.54 ? 471 PHE C C   1 
ATOM   10824 O O   . PHE C 1 463 ? -74.408 33.895  64.474 1.00 131.30 ? 471 PHE C O   1 
ATOM   10825 C CB  . PHE C 1 463 ? -72.044 32.640  66.535 1.00 116.88 ? 471 PHE C CB  1 
ATOM   10826 C CG  . PHE C 1 463 ? -72.291 34.033  67.098 1.00 121.74 ? 471 PHE C CG  1 
ATOM   10827 C CD1 . PHE C 1 463 ? -73.494 34.350  67.728 1.00 128.76 ? 471 PHE C CD1 1 
ATOM   10828 C CD2 . PHE C 1 463 ? -71.332 35.035  66.975 1.00 132.03 ? 471 PHE C CD2 1 
ATOM   10829 C CE1 . PHE C 1 463 ? -73.716 35.618  68.248 1.00 130.92 ? 471 PHE C CE1 1 
ATOM   10830 C CE2 . PHE C 1 463 ? -71.562 36.295  67.493 1.00 149.96 ? 471 PHE C CE2 1 
ATOM   10831 C CZ  . PHE C 1 463 ? -72.757 36.591  68.121 1.00 133.99 ? 471 PHE C CZ  1 
ATOM   10832 N N   . ALA C 1 464 ? -72.408 33.319  63.584 1.00 94.96  ? 472 ALA C N   1 
ATOM   10833 C CA  . ALA C 1 464 ? -72.469 34.284  62.500 1.00 73.96  ? 472 ALA C CA  1 
ATOM   10834 C C   . ALA C 1 464 ? -73.668 34.028  61.588 1.00 80.34  ? 472 ALA C C   1 
ATOM   10835 O O   . ALA C 1 464 ? -74.255 34.995  61.088 1.00 73.03  ? 472 ALA C O   1 
ATOM   10836 C CB  . ALA C 1 464 ? -71.200 34.173  61.682 1.00 93.11  ? 472 ALA C CB  1 
ATOM   10837 N N   . SER C 1 465 ? -73.952 32.727  61.323 1.00 77.14  ? 473 SER C N   1 
ATOM   10838 C CA  . SER C 1 465 ? -75.002 32.323  60.403 1.00 75.70  ? 473 SER C CA  1 
ATOM   10839 C C   . SER C 1 465 ? -76.352 32.765  60.919 1.00 72.79  ? 473 SER C C   1 
ATOM   10840 O O   . SER C 1 465 ? -77.277 32.836  60.141 1.00 73.18  ? 473 SER C O   1 
ATOM   10841 C CB  . SER C 1 465 ? -75.008 30.873  60.111 1.00 72.21  ? 473 SER C CB  1 
ATOM   10842 O OG  . SER C 1 465 ? -73.842 30.526  59.372 1.00 68.12  ? 473 SER C OG  1 
ATOM   10843 N N   . LEU C 1 466 ? -76.448 33.119  62.194 1.00 83.93  ? 474 LEU C N   1 
ATOM   10844 C CA  . LEU C 1 466 ? -77.737 33.486  62.768 1.00 93.91  ? 474 LEU C CA  1 
ATOM   10845 C C   . LEU C 1 466 ? -78.194 34.870  62.286 1.00 86.64  ? 474 LEU C C   1 
ATOM   10846 O O   . LEU C 1 466 ? -79.351 35.223  62.460 1.00 118.13 ? 474 LEU C O   1 
ATOM   10847 C CB  . LEU C 1 466 ? -77.659 33.478  64.291 1.00 107.71 ? 474 LEU C CB  1 
ATOM   10848 C CG  . LEU C 1 466 ? -77.457 32.124  64.967 1.00 108.00 ? 474 LEU C CG  1 
ATOM   10849 C CD1 . LEU C 1 466 ? -77.170 32.353  66.450 1.00 97.21  ? 474 LEU C CD1 1 
ATOM   10850 C CD2 . LEU C 1 466 ? -78.680 31.242  64.782 1.00 102.10 ? 474 LEU C CD2 1 
ATOM   10851 N N   . PHE C 1 467 ? -77.275 35.686  61.770 1.00 64.06  ? 475 PHE C N   1 
ATOM   10852 C CA  . PHE C 1 467 ? -77.611 37.032  61.358 1.00 78.93  ? 475 PHE C CA  1 
ATOM   10853 C C   . PHE C 1 467 ? -77.602 37.174  59.828 1.00 100.15 ? 475 PHE C C   1 
ATOM   10854 O O   . PHE C 1 467 ? -76.918 36.423  59.125 1.00 114.53 ? 475 PHE C O   1 
ATOM   10855 C CB  . PHE C 1 467 ? -76.552 38.004  61.868 1.00 88.32  ? 475 PHE C CB  1 
ATOM   10856 C CG  . PHE C 1 467 ? -76.280 37.956  63.356 1.00 80.52  ? 475 PHE C CG  1 
ATOM   10857 C CD1 . PHE C 1 467 ? -75.401 37.012  63.907 1.00 82.43  ? 475 PHE C CD1 1 
ATOM   10858 C CD2 . PHE C 1 467 ? -76.853 38.919  64.179 1.00 71.49  ? 475 PHE C CD2 1 
ATOM   10859 C CE1 . PHE C 1 467 ? -75.113 37.035  65.276 1.00 110.21 ? 475 PHE C CE1 1 
ATOM   10860 C CE2 . PHE C 1 467 ? -76.601 38.914  65.541 1.00 78.92  ? 475 PHE C CE2 1 
ATOM   10861 C CZ  . PHE C 1 467 ? -75.725 37.989  66.085 1.00 108.15 ? 475 PHE C CZ  1 
ATOM   10862 N N   . PRO C 1 468 ? -78.294 38.202  59.259 1.00 96.03  ? 476 PRO C N   1 
ATOM   10863 C CA  . PRO C 1 468 ? -78.446 38.326  57.810 1.00 70.02  ? 476 PRO C CA  1 
ATOM   10864 C C   . PRO C 1 468 ? -77.159 38.893  57.227 1.00 76.98  ? 476 PRO C C   1 
ATOM   10865 O O   . PRO C 1 468 ? -76.281 39.431  57.963 1.00 65.92  ? 476 PRO C O   1 
ATOM   10866 C CB  . PRO C 1 468 ? -79.649 39.313  57.701 1.00 57.01  ? 476 PRO C CB  1 
ATOM   10867 C CG  . PRO C 1 468 ? -79.502 40.240  58.915 1.00 65.97  ? 476 PRO C CG  1 
ATOM   10868 C CD  . PRO C 1 468 ? -78.937 39.321  59.992 1.00 88.12  ? 476 PRO C CD  1 
ATOM   10869 N N   . LEU C 1 469 ? -77.087 38.787  55.879 1.00 65.98  ? 477 LEU C N   1 
ATOM   10870 C CA  . LEU C 1 469 ? -75.881 39.260  55.194 1.00 77.49  ? 477 LEU C CA  1 
ATOM   10871 C C   . LEU C 1 469 ? -76.225 40.185  54.047 1.00 57.16  ? 477 LEU C C   1 
ATOM   10872 O O   . LEU C 1 469 ? -76.456 39.680  52.948 1.00 58.10  ? 477 LEU C O   1 
ATOM   10873 C CB  . LEU C 1 469 ? -75.121 38.057  54.636 1.00 113.30 ? 477 LEU C CB  1 
ATOM   10874 C CG  . LEU C 1 469 ? -73.841 38.352  53.860 1.00 98.54  ? 477 LEU C CG  1 
ATOM   10875 C CD1 . LEU C 1 469 ? -72.787 38.609  54.936 1.00 96.48  ? 477 LEU C CD1 1 
ATOM   10876 C CD2 . LEU C 1 469 ? -73.583 37.173  52.891 1.00 93.32  ? 477 LEU C CD2 1 
ATOM   10877 N N   . PRO C 1 470 ? -76.138 41.523  54.217 1.00 53.57  ? 478 PRO C N   1 
ATOM   10878 C CA  . PRO C 1 470 ? -76.704 42.479  53.261 1.00 53.97  ? 478 PRO C CA  1 
ATOM   10879 C C   . PRO C 1 470 ? -76.240 42.192  51.833 1.00 85.11  ? 478 PRO C C   1 
ATOM   10880 O O   . PRO C 1 470 ? -75.067 41.856  51.617 1.00 71.53  ? 478 PRO C O   1 
ATOM   10881 C CB  . PRO C 1 470 ? -76.205 43.859  53.741 1.00 42.02  ? 478 PRO C CB  1 
ATOM   10882 C CG  . PRO C 1 470 ? -75.947 43.653  55.206 1.00 49.15  ? 478 PRO C CG  1 
ATOM   10883 C CD  . PRO C 1 470 ? -75.488 42.182  55.355 1.00 64.39  ? 478 PRO C CD  1 
ATOM   10884 N N   . GLY C 1 471 ? -77.163 42.393  50.875 1.00 104.67 ? 479 GLY C N   1 
ATOM   10885 C CA  . GLY C 1 471 ? -76.846 42.163  49.479 1.00 92.93  ? 479 GLY C CA  1 
ATOM   10886 C C   . GLY C 1 471 ? -77.525 40.893  48.993 1.00 99.17  ? 479 GLY C C   1 
ATOM   10887 O O   . GLY C 1 471 ? -78.070 40.122  49.802 1.00 125.16 ? 479 GLY C O   1 
ATOM   10888 N N   . LEU C 1 472 ? -77.505 40.706  47.671 1.00 70.54  ? 480 LEU C N   1 
ATOM   10889 C CA  . LEU C 1 472 ? -78.159 39.556  47.062 1.00 82.70  ? 480 LEU C CA  1 
ATOM   10890 C C   . LEU C 1 472 ? -78.077 39.782  45.550 1.00 81.56  ? 480 LEU C C   1 
ATOM   10891 O O   . LEU C 1 472 ? -78.787 39.011  44.883 1.00 120.92 ? 480 LEU C O   1 
ATOM   10892 C CB  . LEU C 1 472 ? -79.603 39.220  47.524 1.00 101.35 ? 480 LEU C CB  1 
ATOM   10893 C CG  . LEU C 1 472 ? -79.935 37.768  47.959 1.00 106.43 ? 480 LEU C CG  1 
ATOM   10894 C CD1 . LEU C 1 472 ? -79.213 37.171  49.252 1.00 68.68  ? 480 LEU C CD1 1 
ATOM   10895 C CD2 . LEU C 1 472 ? -81.465 37.503  48.036 1.00 89.45  ? 480 LEU C CD2 1 
ATOM   10896 O OXT . LEU C 1 472 ? -77.342 40.730  45.083 1.00 46.83  ? 480 LEU C OXT 1 
ATOM   10897 N N   . GLN D 1 1   ? 6.564   77.848  69.679 1.00 87.61  ? 9   GLN D N   1 
ATOM   10898 C CA  . GLN D 1 1   ? 5.672   78.777  70.417 1.00 121.56 ? 9   GLN D CA  1 
ATOM   10899 C C   . GLN D 1 1   ? 6.083   80.213  70.098 1.00 140.27 ? 9   GLN D C   1 
ATOM   10900 O O   . GLN D 1 1   ? 5.937   80.620  68.930 1.00 99.51  ? 9   GLN D O   1 
ATOM   10901 C CB  . GLN D 1 1   ? 5.761   78.509  71.918 1.00 30.00  ? 9   GLN D CB  1 
ATOM   10902 C CG  . GLN D 1 1   ? 7.158   78.144  72.393 1.00 30.00  ? 9   GLN D CG  1 
ATOM   10903 C CD  . GLN D 1 1   ? 7.530   78.901  73.644 1.00 30.00  ? 9   GLN D CD  1 
ATOM   10904 O OE1 . GLN D 1 1   ? 6.703   79.574  74.254 1.00 30.00  ? 9   GLN D OE1 1 
ATOM   10905 N NE2 . GLN D 1 1   ? 8.789   78.793  74.037 1.00 30.00  ? 9   GLN D NE2 1 
ATOM   10906 N N   . GLY D 1 2   ? 6.553   80.959  71.101 1.00 146.16 ? 10  GLY D N   1 
ATOM   10907 C CA  . GLY D 1 2   ? 7.064   82.311  70.822 1.00 119.17 ? 10  GLY D CA  1 
ATOM   10908 C C   . GLY D 1 2   ? 8.050   82.233  69.678 1.00 155.01 ? 10  GLY D C   1 
ATOM   10909 O O   . GLY D 1 2   ? 7.789   82.894  68.664 1.00 160.75 ? 10  GLY D O   1 
ATOM   10910 N N   . ASP D 1 3   ? 9.092   81.402  69.812 1.00 137.95 ? 11  ASP D N   1 
ATOM   10911 C CA  . ASP D 1 3   ? 10.140  81.253  68.766 1.00 105.08 ? 11  ASP D CA  1 
ATOM   10912 C C   . ASP D 1 3   ? 9.946   82.325  67.705 1.00 107.56 ? 11  ASP D C   1 
ATOM   10913 O O   . ASP D 1 3   ? 9.653   81.972  66.555 1.00 107.08 ? 11  ASP D O   1 
ATOM   10914 C CB  . ASP D 1 3   ? 10.126  79.874  68.115 1.00 100.61 ? 11  ASP D CB  1 
ATOM   10915 C CG  . ASP D 1 3   ? 11.370  79.590  67.292 1.00 117.42 ? 11  ASP D CG  1 
ATOM   10916 O OD1 . ASP D 1 3   ? 12.058  80.557  66.917 1.00 75.72  ? 11  ASP D OD1 1 
ATOM   10917 O OD2 . ASP D 1 3   ? 11.641  78.404  67.033 1.00 150.00 ? 11  ASP D OD2 1 
ATOM   10918 N N   . ALA D 1 4   ? 10.086  83.587  68.099 1.00 124.07 ? 12  ALA D N   1 
ATOM   10919 C CA  . ALA D 1 4   ? 9.861   84.681  67.141 1.00 94.60  ? 12  ALA D CA  1 
ATOM   10920 C C   . ALA D 1 4   ? 10.563  84.291  65.851 1.00 93.99  ? 12  ALA D C   1 
ATOM   10921 O O   . ALA D 1 4   ? 9.972   84.447  64.774 1.00 95.47  ? 12  ALA D O   1 
ATOM   10922 C CB  . ALA D 1 4   ? 10.410  85.954  67.700 1.00 43.63  ? 12  ALA D CB  1 
ATOM   10923 N N   . ASP D 1 5   ? 11.780  83.776  65.984 1.00 78.36  ? 13  ASP D N   1 
ATOM   10924 C CA  . ASP D 1 5   ? 12.529  83.342  64.785 1.00 100.79 ? 13  ASP D CA  1 
ATOM   10925 C C   . ASP D 1 5   ? 11.554  82.592  63.878 1.00 115.96 ? 13  ASP D C   1 
ATOM   10926 O O   . ASP D 1 5   ? 11.416  82.979  62.708 1.00 87.68  ? 13  ASP D O   1 
ATOM   10927 C CB  . ASP D 1 5   ? 13.752  82.521  65.187 1.00 123.51 ? 13  ASP D CB  1 
ATOM   10928 C CG  . ASP D 1 5   ? 14.811  83.344  65.897 1.00 126.64 ? 13  ASP D CG  1 
ATOM   10929 O OD1 . ASP D 1 5   ? 14.757  84.583  65.786 1.00 84.75  ? 13  ASP D OD1 1 
ATOM   10930 O OD2 . ASP D 1 5   ? 15.680  82.740  66.552 1.00 124.87 ? 13  ASP D OD2 1 
ATOM   10931 N N   . LEU D 1 6   ? 10.888  81.573  64.417 1.00 137.84 ? 14  LEU D N   1 
ATOM   10932 C CA  . LEU D 1 6   ? 9.962   80.767  63.581 1.00 116.59 ? 14  LEU D CA  1 
ATOM   10933 C C   . LEU D 1 6   ? 8.840   81.681  63.104 1.00 113.09 ? 14  LEU D C   1 
ATOM   10934 O O   . LEU D 1 6   ? 8.521   81.657  61.908 1.00 95.61  ? 14  LEU D O   1 
ATOM   10935 C CB  . LEU D 1 6   ? 9.395   79.603  64.396 1.00 89.09  ? 14  LEU D CB  1 
ATOM   10936 C CG  . LEU D 1 6   ? 8.585   78.589  63.597 1.00 68.52  ? 14  LEU D CG  1 
ATOM   10937 C CD1 . LEU D 1 6   ? 9.316   78.209  62.322 1.00 47.95  ? 14  LEU D CD1 1 
ATOM   10938 C CD2 . LEU D 1 6   ? 8.306   77.356  64.435 1.00 76.87  ? 14  LEU D CD2 1 
ATOM   10939 N N   . TRP D 1 7   ? 8.269   82.460  64.016 1.00 111.49 ? 15  TRP D N   1 
ATOM   10940 C CA  . TRP D 1 7   ? 7.122   83.290  63.591 1.00 118.26 ? 15  TRP D CA  1 
ATOM   10941 C C   . TRP D 1 7   ? 7.596   84.119  62.406 1.00 136.79 ? 15  TRP D C   1 
ATOM   10942 O O   . TRP D 1 7   ? 6.866   84.203  61.407 1.00 164.54 ? 15  TRP D O   1 
ATOM   10943 C CB  . TRP D 1 7   ? 6.620   84.171  64.731 1.00 97.40  ? 15  TRP D CB  1 
ATOM   10944 C CG  . TRP D 1 7   ? 5.243   84.700  64.491 1.00 105.56 ? 15  TRP D CG  1 
ATOM   10945 C CD1 . TRP D 1 7   ? 4.884   85.995  64.264 1.00 102.65 ? 15  TRP D CD1 1 
ATOM   10946 C CD2 . TRP D 1 7   ? 4.031   83.930  64.432 1.00 117.79 ? 15  TRP D CD2 1 
ATOM   10947 N NE1 . TRP D 1 7   ? 3.532   86.084  64.080 1.00 106.28 ? 15  TRP D NE1 1 
ATOM   10948 C CE2 . TRP D 1 7   ? 2.982   84.835  64.176 1.00 113.15 ? 15  TRP D CE2 1 
ATOM   10949 C CE3 . TRP D 1 7   ? 3.732   82.572  64.574 1.00 160.40 ? 15  TRP D CE3 1 
ATOM   10950 C CZ2 . TRP D 1 7   ? 1.657   84.422  64.061 1.00 150.39 ? 15  TRP D CZ2 1 
ATOM   10951 C CZ3 . TRP D 1 7   ? 2.423   82.165  64.459 1.00 172.92 ? 15  TRP D CZ3 1 
ATOM   10952 C CH2 . TRP D 1 7   ? 1.401   83.079  64.205 1.00 167.16 ? 15  TRP D CH2 1 
ATOM   10953 N N   . SER D 1 8   ? 8.796   84.681  62.506 1.00 119.98 ? 16  SER D N   1 
ATOM   10954 C CA  . SER D 1 8   ? 9.325   85.411  61.334 1.00 128.73 ? 16  SER D CA  1 
ATOM   10955 C C   . SER D 1 8   ? 9.451   84.423  60.179 1.00 133.86 ? 16  SER D C   1 
ATOM   10956 O O   . SER D 1 8   ? 8.877   84.690  59.113 1.00 152.27 ? 16  SER D O   1 
ATOM   10957 C CB  . SER D 1 8   ? 10.635  86.046  61.642 1.00 130.44 ? 16  SER D CB  1 
ATOM   10958 O OG  . SER D 1 8   ? 11.125  86.747  60.508 1.00 168.72 ? 16  SER D OG  1 
ATOM   10959 N N   . SER D 1 9   ? 10.146  83.309  60.402 1.00 108.40 ? 17  SER D N   1 
ATOM   10960 C CA  . SER D 1 9   ? 10.221  82.289  59.333 1.00 119.14 ? 17  SER D CA  1 
ATOM   10961 C C   . SER D 1 9   ? 8.838   82.207  58.714 1.00 120.73 ? 17  SER D C   1 
ATOM   10962 O O   . SER D 1 9   ? 8.731   82.068  57.487 1.00 130.25 ? 17  SER D O   1 
ATOM   10963 C CB  . SER D 1 9   ? 10.629  80.956  59.854 1.00 106.65 ? 17  SER D CB  1 
ATOM   10964 O OG  . SER D 1 9   ? 10.536  79.976  58.833 1.00 94.93  ? 17  SER D OG  1 
ATOM   10965 N N   . HIS D 1 10  ? 7.823   82.316  59.560 1.00 91.67  ? 18  HIS D N   1 
ATOM   10966 C CA  . HIS D 1 10  ? 6.473   82.187  59.033 1.00 100.37 ? 18  HIS D CA  1 
ATOM   10967 C C   . HIS D 1 10  ? 6.098   83.429  58.209 1.00 104.37 ? 18  HIS D C   1 
ATOM   10968 O O   . HIS D 1 10  ? 5.568   83.318  57.091 1.00 101.10 ? 18  HIS D O   1 
ATOM   10969 C CB  . HIS D 1 10  ? 5.483   81.841  60.156 1.00 71.34  ? 18  HIS D CB  1 
ATOM   10970 C CG  . HIS D 1 10  ? 4.048   81.989  59.765 1.00 84.45  ? 18  HIS D CG  1 
ATOM   10971 N ND1 . HIS D 1 10  ? 3.364   83.189  59.792 1.00 96.60  ? 18  HIS D ND1 1 
ATOM   10972 C CD2 . HIS D 1 10  ? 3.172   81.071  59.291 1.00 101.24 ? 18  HIS D CD2 1 
ATOM   10973 C CE1 . HIS D 1 10  ? 2.113   82.994  59.370 1.00 107.69 ? 18  HIS D CE1 1 
ATOM   10974 N NE2 . HIS D 1 10  ? 1.963   81.711  59.082 1.00 108.91 ? 18  HIS D NE2 1 
ATOM   10975 N N   . ASP D 1 11  ? 6.314   84.628  58.786 1.00 97.41  ? 19  ASP D N   1 
ATOM   10976 C CA  . ASP D 1 11  ? 6.004   85.874  58.100 1.00 88.27  ? 19  ASP D CA  1 
ATOM   10977 C C   . ASP D 1 11  ? 6.745   85.836  56.771 1.00 108.12 ? 19  ASP D C   1 
ATOM   10978 O O   . ASP D 1 11  ? 6.248   86.316  55.743 1.00 131.00 ? 19  ASP D O   1 
ATOM   10979 C CB  . ASP D 1 11  ? 6.518   87.085  58.869 1.00 80.87  ? 19  ASP D CB  1 
ATOM   10980 C CG  . ASP D 1 11  ? 5.580   87.682  59.908 1.00 120.77 ? 19  ASP D CG  1 
ATOM   10981 O OD1 . ASP D 1 11  ? 4.694   88.445  59.471 1.00 116.35 ? 19  ASP D OD1 1 
ATOM   10982 O OD2 . ASP D 1 11  ? 5.743   87.383  61.145 1.00 116.93 ? 19  ASP D OD2 1 
ATOM   10983 N N   . ALA D 1 12  ? 7.949   85.246  56.841 1.00 76.23  ? 20  ALA D N   1 
ATOM   10984 C CA  . ALA D 1 12  ? 8.863   85.251  55.715 1.00 76.69  ? 20  ALA D CA  1 
ATOM   10985 C C   . ALA D 1 12  ? 8.275   84.413  54.581 1.00 85.81  ? 20  ALA D C   1 
ATOM   10986 O O   . ALA D 1 12  ? 8.262   84.825  53.400 1.00 67.59  ? 20  ALA D O   1 
ATOM   10987 C CB  . ALA D 1 12  ? 10.206  84.753  56.144 1.00 65.18  ? 20  ALA D CB  1 
ATOM   10988 N N   . MET D 1 13  ? 7.760   83.231  54.971 1.00 89.33  ? 21  MET D N   1 
ATOM   10989 C CA  . MET D 1 13  ? 7.236   82.256  54.028 1.00 96.18  ? 21  MET D CA  1 
ATOM   10990 C C   . MET D 1 13  ? 6.278   82.966  53.093 1.00 93.34  ? 21  MET D C   1 
ATOM   10991 O O   . MET D 1 13  ? 6.419   82.868  51.868 1.00 74.88  ? 21  MET D O   1 
ATOM   10992 C CB  . MET D 1 13  ? 6.372   81.222  54.761 1.00 77.35  ? 21  MET D CB  1 
ATOM   10993 C CG  . MET D 1 13  ? 5.958   80.062  53.855 1.00 59.23  ? 21  MET D CG  1 
ATOM   10994 S SD  . MET D 1 13  ? 4.895   78.923  54.784 1.00 58.40  ? 21  MET D SD  1 
ATOM   10995 C CE  . MET D 1 13  ? 5.186   78.956  56.567 1.00 51.88  ? 21  MET D CE  1 
ATOM   10996 N N   . LEU D 1 14  ? 5.326   83.665  53.743 1.00 81.59  ? 22  LEU D N   1 
ATOM   10997 C CA  . LEU D 1 14  ? 4.191   84.273  53.084 1.00 70.29  ? 22  LEU D CA  1 
ATOM   10998 C C   . LEU D 1 14  ? 4.653   85.331  52.104 1.00 99.84  ? 22  LEU D C   1 
ATOM   10999 O O   . LEU D 1 14  ? 3.877   85.686  51.215 1.00 123.81 ? 22  LEU D O   1 
ATOM   11000 C CB  . LEU D 1 14  ? 3.186   84.823  54.073 1.00 60.30  ? 22  LEU D CB  1 
ATOM   11001 C CG  . LEU D 1 14  ? 2.614   83.737  54.993 1.00 97.06  ? 22  LEU D CG  1 
ATOM   11002 C CD1 . LEU D 1 14  ? 1.714   84.271  56.103 1.00 92.78  ? 22  LEU D CD1 1 
ATOM   11003 C CD2 . LEU D 1 14  ? 1.930   82.628  54.191 1.00 107.04 ? 22  LEU D CD2 1 
ATOM   11004 N N   . ALA D 1 15  ? 5.908   85.783  52.238 1.00 93.75  ? 23  ALA D N   1 
ATOM   11005 C CA  . ALA D 1 15  ? 6.348   86.885  51.392 1.00 71.32  ? 23  ALA D CA  1 
ATOM   11006 C C   . ALA D 1 15  ? 7.385   86.448  50.356 1.00 81.68  ? 23  ALA D C   1 
ATOM   11007 O O   . ALA D 1 15  ? 7.658   87.182  49.404 1.00 89.03  ? 23  ALA D O   1 
ATOM   11008 C CB  . ALA D 1 15  ? 6.839   88.009  52.252 1.00 50.93  ? 23  ALA D CB  1 
ATOM   11009 N N   . GLN D 1 16  ? 7.944   85.241  50.519 1.00 79.11  ? 24  GLN D N   1 
ATOM   11010 C CA  . GLN D 1 16  ? 8.982   84.757  49.625 1.00 79.23  ? 24  GLN D CA  1 
ATOM   11011 C C   . GLN D 1 16  ? 8.414   84.429  48.239 1.00 64.93  ? 24  GLN D C   1 
ATOM   11012 O O   . GLN D 1 16  ? 7.315   83.889  48.115 1.00 81.66  ? 24  GLN D O   1 
ATOM   11013 C CB  . GLN D 1 16  ? 9.560   83.590  50.422 1.00 102.86 ? 24  GLN D CB  1 
ATOM   11014 C CG  . GLN D 1 16  ? 10.739  82.900  49.753 1.00 120.54 ? 24  GLN D CG  1 
ATOM   11015 C CD  . GLN D 1 16  ? 10.827  81.446  50.144 1.00 131.93 ? 24  GLN D CD  1 
ATOM   11016 O OE1 . GLN D 1 16  ? 9.908   80.869  50.728 1.00 159.87 ? 24  GLN D OE1 1 
ATOM   11017 N NE2 . GLN D 1 16  ? 11.921  80.824  49.746 1.00 168.71 ? 24  GLN D NE2 1 
ATOM   11018 N N   . PRO D 1 17  ? 9.137   84.774  47.142 1.00 66.80  ? 25  PRO D N   1 
ATOM   11019 C CA  . PRO D 1 17  ? 8.695   84.561  45.762 1.00 75.43  ? 25  PRO D CA  1 
ATOM   11020 C C   . PRO D 1 17  ? 8.410   83.120  45.424 1.00 92.16  ? 25  PRO D C   1 
ATOM   11021 O O   . PRO D 1 17  ? 8.923   82.209  46.075 1.00 104.02 ? 25  PRO D O   1 
ATOM   11022 C CB  . PRO D 1 17  ? 9.861   85.047  44.886 1.00 65.14  ? 25  PRO D CB  1 
ATOM   11023 C CG  . PRO D 1 17  ? 10.470  86.112  45.735 1.00 94.75  ? 25  PRO D CG  1 
ATOM   11024 C CD  . PRO D 1 17  ? 10.417  85.492  47.155 1.00 103.76 ? 25  PRO D CD  1 
ATOM   11025 N N   . LEU D 1 18  ? 7.658   82.971  44.335 1.00 95.94  ? 26  LEU D N   1 
ATOM   11026 C CA  . LEU D 1 18  ? 7.293   81.679  43.776 1.00 97.10  ? 26  LEU D CA  1 
ATOM   11027 C C   . LEU D 1 18  ? 8.554   80.909  43.426 1.00 97.46  ? 26  LEU D C   1 
ATOM   11028 O O   . LEU D 1 18  ? 8.636   79.708  43.729 1.00 63.29  ? 26  LEU D O   1 
ATOM   11029 C CB  . LEU D 1 18  ? 6.488   81.908  42.494 1.00 96.20  ? 26  LEU D CB  1 
ATOM   11030 C CG  . LEU D 1 18  ? 5.803   80.682  41.882 1.00 82.75  ? 26  LEU D CG  1 
ATOM   11031 C CD1 . LEU D 1 18  ? 5.145   79.777  42.937 1.00 91.84  ? 26  LEU D CD1 1 
ATOM   11032 C CD2 . LEU D 1 18  ? 4.676   81.213  40.938 1.00 43.87  ? 26  LEU D CD2 1 
ATOM   11033 N N   . LYS D 1 19  ? 9.479   81.623  42.758 1.00 91.08  ? 27  LYS D N   1 
ATOM   11034 C CA  . LYS D 1 19  ? 10.724  81.020  42.297 1.00 101.03 ? 27  LYS D CA  1 
ATOM   11035 C C   . LYS D 1 19  ? 11.361  80.218  43.439 1.00 91.30  ? 27  LYS D C   1 
ATOM   11036 O O   . LYS D 1 19  ? 11.927  79.147  43.229 1.00 98.37  ? 27  LYS D O   1 
ATOM   11037 C CB  . LYS D 1 19  ? 11.707  81.971  41.592 1.00 127.93 ? 27  LYS D CB  1 
ATOM   11038 C CG  . LYS D 1 19  ? 13.093  81.306  41.316 1.00 120.88 ? 27  LYS D CG  1 
ATOM   11039 C CD  . LYS D 1 19  ? 14.246  81.929  40.523 1.00 124.01 ? 27  LYS D CD  1 
ATOM   11040 C CE  . LYS D 1 19  ? 15.435  82.555  41.216 1.00 133.24 ? 27  LYS D CE  1 
ATOM   11041 N NZ  . LYS D 1 19  ? 16.641  81.726  41.238 1.00 117.82 ? 27  LYS D NZ  1 
ATOM   11042 N N   . ASP D 1 20  ? 11.251  80.752  44.666 1.00 66.65  ? 28  ASP D N   1 
ATOM   11043 C CA  . ASP D 1 20  ? 12.031  80.295  45.802 1.00 65.70  ? 28  ASP D CA  1 
ATOM   11044 C C   . ASP D 1 20  ? 11.203  79.342  46.655 1.00 86.42  ? 28  ASP D C   1 
ATOM   11045 O O   . ASP D 1 20  ? 11.720  78.368  47.181 1.00 131.27 ? 28  ASP D O   1 
ATOM   11046 C CB  . ASP D 1 20  ? 12.534  81.465  46.627 1.00 63.92  ? 28  ASP D CB  1 
ATOM   11047 C CG  . ASP D 1 20  ? 13.032  82.707  45.879 1.00 92.74  ? 28  ASP D CG  1 
ATOM   11048 O OD1 . ASP D 1 20  ? 13.066  82.744  44.596 1.00 98.66  ? 28  ASP D OD1 1 
ATOM   11049 O OD2 . ASP D 1 20  ? 13.437  83.645  46.573 1.00 78.88  ? 28  ASP D OD2 1 
ATOM   11050 N N   . SER D 1 21  ? 9.904   79.624  46.768 1.00 100.76 ? 29  SER D N   1 
ATOM   11051 C CA  . SER D 1 21  ? 8.967   78.733  47.426 1.00 90.95  ? 29  SER D CA  1 
ATOM   11052 C C   . SER D 1 21  ? 8.385   77.828  46.342 1.00 95.86  ? 29  SER D C   1 
ATOM   11053 O O   . SER D 1 21  ? 7.761   78.303  45.370 1.00 93.85  ? 29  SER D O   1 
ATOM   11054 C CB  . SER D 1 21  ? 7.863   79.497  48.077 1.00 76.20  ? 29  SER D CB  1 
ATOM   11055 O OG  . SER D 1 21  ? 6.870   78.577  48.535 1.00 63.56  ? 29  SER D OG  1 
ATOM   11056 N N   . ASP D 1 22  ? 8.562   76.518  46.533 1.00 82.51  ? 30  ASP D N   1 
ATOM   11057 C CA  . ASP D 1 22  ? 7.954   75.599  45.579 1.00 114.12 ? 30  ASP D CA  1 
ATOM   11058 C C   . ASP D 1 22  ? 8.457   75.961  44.182 1.00 120.82 ? 30  ASP D C   1 
ATOM   11059 O O   . ASP D 1 22  ? 7.778   76.535  43.297 1.00 94.01  ? 30  ASP D O   1 
ATOM   11060 C CB  . ASP D 1 22  ? 6.448   75.647  45.684 1.00 104.47 ? 30  ASP D CB  1 
ATOM   11061 C CG  . ASP D 1 22  ? 5.702   74.656  44.818 1.00 103.43 ? 30  ASP D CG  1 
ATOM   11062 O OD1 . ASP D 1 22  ? 6.352   73.973  43.921 1.00 111.46 ? 30  ASP D OD1 1 
ATOM   11063 O OD2 . ASP D 1 22  ? 4.483   74.662  45.038 1.00 95.68  ? 30  ASP D OD2 1 
ATOM   11064 N N   . VAL D 1 23  ? 9.699   75.531  44.004 1.00 96.94  ? 31  VAL D N   1 
ATOM   11065 C CA  . VAL D 1 23  ? 10.367  75.592  42.730 1.00 79.46  ? 31  VAL D CA  1 
ATOM   11066 C C   . VAL D 1 23  ? 9.683   74.684  41.721 1.00 97.20  ? 31  VAL D C   1 
ATOM   11067 O O   . VAL D 1 23  ? 9.669   75.007  40.527 1.00 81.66  ? 31  VAL D O   1 
ATOM   11068 C CB  . VAL D 1 23  ? 11.697  74.945  43.078 1.00 55.51  ? 31  VAL D CB  1 
ATOM   11069 C CG1 . VAL D 1 23  ? 12.483  74.810  41.774 1.00 47.37  ? 31  VAL D CG1 1 
ATOM   11070 C CG2 . VAL D 1 23  ? 12.399  75.681  44.248 1.00 64.81  ? 31  VAL D CG2 1 
ATOM   11071 N N   . GLU D 1 24  ? 9.174   73.529  42.206 1.00 111.13 ? 32  GLU D N   1 
ATOM   11072 C CA  . GLU D 1 24  ? 8.590   72.557  41.285 1.00 102.30 ? 32  GLU D CA  1 
ATOM   11073 C C   . GLU D 1 24  ? 7.547   73.254  40.419 1.00 98.06  ? 32  GLU D C   1 
ATOM   11074 O O   . GLU D 1 24  ? 7.630   73.195  39.196 1.00 94.14  ? 32  GLU D O   1 
ATOM   11075 C CB  . GLU D 1 24  ? 7.920   71.351  41.938 1.00 78.99  ? 32  GLU D CB  1 
ATOM   11076 C CG  . GLU D 1 24  ? 8.629   70.802  43.178 1.00 69.37  ? 32  GLU D CG  1 
ATOM   11077 C CD  . GLU D 1 24  ? 8.254   69.300  43.168 1.00 85.20  ? 32  GLU D CD  1 
ATOM   11078 O OE1 . GLU D 1 24  ? 7.803   68.758  44.265 1.00 65.53  ? 32  GLU D OE1 1 
ATOM   11079 O OE2 . GLU D 1 24  ? 8.366   68.683  42.014 1.00 52.51  ? 32  GLU D OE2 1 
ATOM   11080 N N   . VAL D 1 25  ? 6.669   74.026  41.071 1.00 92.02  ? 33  VAL D N   1 
ATOM   11081 C CA  . VAL D 1 25  ? 5.608   74.688  40.351 1.00 99.38  ? 33  VAL D CA  1 
ATOM   11082 C C   . VAL D 1 25  ? 6.190   75.768  39.446 1.00 116.99 ? 33  VAL D C   1 
ATOM   11083 O O   . VAL D 1 25  ? 5.827   75.843  38.268 1.00 119.82 ? 33  VAL D O   1 
ATOM   11084 C CB  . VAL D 1 25  ? 4.530   75.238  41.291 1.00 84.69  ? 33  VAL D CB  1 
ATOM   11085 C CG1 . VAL D 1 25  ? 3.609   76.205  40.548 1.00 84.12  ? 33  VAL D CG1 1 
ATOM   11086 C CG2 . VAL D 1 25  ? 3.752   74.092  41.945 1.00 53.47  ? 33  VAL D CG2 1 
ATOM   11087 N N   . TYR D 1 26  ? 7.055   76.625  40.016 1.00 98.01  ? 34  TYR D N   1 
ATOM   11088 C CA  . TYR D 1 26  ? 7.720   77.662  39.236 1.00 98.65  ? 34  TYR D CA  1 
ATOM   11089 C C   . TYR D 1 26  ? 8.227   77.083  37.901 1.00 113.85 ? 34  TYR D C   1 
ATOM   11090 O O   . TYR D 1 26  ? 7.994   77.660  36.810 1.00 97.83  ? 34  TYR D O   1 
ATOM   11091 C CB  . TYR D 1 26  ? 8.788   78.336  40.092 1.00 87.24  ? 34  TYR D CB  1 
ATOM   11092 C CG  . TYR D 1 26  ? 9.580   79.386  39.318 1.00 113.60 ? 34  TYR D CG  1 
ATOM   11093 C CD1 . TYR D 1 26  ? 9.162   80.711  39.228 1.00 126.59 ? 34  TYR D CD1 1 
ATOM   11094 C CD2 . TYR D 1 26  ? 10.784  79.057  38.717 1.00 113.57 ? 34  TYR D CD2 1 
ATOM   11095 C CE1 . TYR D 1 26  ? 9.891   81.659  38.527 1.00 118.53 ? 34  TYR D CE1 1 
ATOM   11096 C CE2 . TYR D 1 26  ? 11.524  79.993  38.009 1.00 101.53 ? 34  TYR D CE2 1 
ATOM   11097 C CZ  . TYR D 1 26  ? 11.071  81.293  37.905 1.00 111.53 ? 34  TYR D CZ  1 
ATOM   11098 O OH  . TYR D 1 26  ? 11.825  82.206  37.231 1.00 131.41 ? 34  TYR D OH  1 
ATOM   11099 N N   . ASN D 1 27  ? 8.878   75.905  37.985 1.00 90.26  ? 35  ASN D N   1 
ATOM   11100 C CA  . ASN D 1 27  ? 9.430   75.333  36.760 1.00 92.64  ? 35  ASN D CA  1 
ATOM   11101 C C   . ASN D 1 27  ? 8.315   74.943  35.803 1.00 87.75  ? 35  ASN D C   1 
ATOM   11102 O O   . ASN D 1 27  ? 8.386   75.249  34.605 1.00 75.19  ? 35  ASN D O   1 
ATOM   11103 C CB  . ASN D 1 27  ? 10.321  74.110  36.935 1.00 84.04  ? 35  ASN D CB  1 
ATOM   11104 C CG  . ASN D 1 27  ? 11.535  74.415  37.784 1.00 106.47 ? 35  ASN D CG  1 
ATOM   11105 O OD1 . ASN D 1 27  ? 12.125  75.502  37.709 1.00 103.69 ? 35  ASN D OD1 1 
ATOM   11106 N ND2 . ASN D 1 27  ? 11.907  73.475  38.640 1.00 141.17 ? 35  ASN D ND2 1 
ATOM   11107 N N   . ILE D 1 28  ? 7.300   74.271  36.362 1.00 82.95  ? 36  ILE D N   1 
ATOM   11108 C CA  . ILE D 1 28  ? 6.175   73.819  35.566 1.00 90.81  ? 36  ILE D CA  1 
ATOM   11109 C C   . ILE D 1 28  ? 5.643   75.016  34.776 1.00 93.23  ? 36  ILE D C   1 
ATOM   11110 O O   . ILE D 1 28  ? 5.523   74.942  33.536 1.00 64.86  ? 36  ILE D O   1 
ATOM   11111 C CB  . ILE D 1 28  ? 5.067   73.181  36.425 1.00 83.67  ? 36  ILE D CB  1 
ATOM   11112 C CG1 . ILE D 1 28  ? 5.556   71.953  37.192 1.00 66.28  ? 36  ILE D CG1 1 
ATOM   11113 C CG2 . ILE D 1 28  ? 3.874   72.833  35.513 1.00 76.04  ? 36  ILE D CG2 1 
ATOM   11114 C CD1 . ILE D 1 28  ? 4.422   71.075  37.711 1.00 69.43  ? 36  ILE D CD1 1 
ATOM   11115 N N   . ILE D 1 29  ? 5.360   76.124  35.491 1.00 71.49  ? 37  ILE D N   1 
ATOM   11116 C CA  . ILE D 1 29  ? 4.847   77.304  34.816 1.00 74.28  ? 37  ILE D CA  1 
ATOM   11117 C C   . ILE D 1 29  ? 5.775   77.713  33.660 1.00 85.41  ? 37  ILE D C   1 
ATOM   11118 O O   . ILE D 1 29  ? 5.309   77.975  32.523 1.00 78.73  ? 37  ILE D O   1 
ATOM   11119 C CB  . ILE D 1 29  ? 4.593   78.483  35.765 1.00 52.63  ? 37  ILE D CB  1 
ATOM   11120 C CG1 . ILE D 1 29  ? 3.719   78.088  36.922 1.00 57.93  ? 37  ILE D CG1 1 
ATOM   11121 C CG2 . ILE D 1 29  ? 3.952   79.638  34.988 1.00 49.94  ? 37  ILE D CG2 1 
ATOM   11122 C CD1 . ILE D 1 29  ? 3.573   79.164  38.003 1.00 41.44  ? 37  ILE D CD1 1 
ATOM   11123 N N   . LYS D 1 30  ? 7.084   77.803  33.969 1.00 60.93  ? 38  LYS D N   1 
ATOM   11124 C CA  . LYS D 1 30  ? 8.024   78.215  32.940 1.00 71.83  ? 38  LYS D CA  1 
ATOM   11125 C C   . LYS D 1 30  ? 8.075   77.216  31.783 1.00 89.80  ? 38  LYS D C   1 
ATOM   11126 O O   . LYS D 1 30  ? 8.024   77.647  30.634 1.00 103.38 ? 38  LYS D O   1 
ATOM   11127 C CB  . LYS D 1 30  ? 9.334   78.715  33.537 1.00 64.80  ? 38  LYS D CB  1 
ATOM   11128 C CG  . LYS D 1 30  ? 9.252   80.211  33.923 1.00 71.58  ? 38  LYS D CG  1 
ATOM   11129 C CD  . LYS D 1 30  ? 10.477  81.058  34.304 1.00 80.07  ? 38  LYS D CD  1 
ATOM   11130 C CE  . LYS D 1 30  ? 11.746  81.225  33.411 1.00 111.32 ? 38  LYS D CE  1 
ATOM   11131 N NZ  . LYS D 1 30  ? 11.981  82.286  32.393 1.00 79.82  ? 38  LYS D NZ  1 
ATOM   11132 N N   . LYS D 1 31  ? 8.146   75.907  32.085 1.00 78.68  ? 39  LYS D N   1 
ATOM   11133 C CA  . LYS D 1 31  ? 8.108   74.889  31.037 1.00 92.50  ? 39  LYS D CA  1 
ATOM   11134 C C   . LYS D 1 31  ? 6.870   75.067  30.138 1.00 116.11 ? 39  LYS D C   1 
ATOM   11135 O O   . LYS D 1 31  ? 6.947   74.888  28.918 1.00 139.51 ? 39  LYS D O   1 
ATOM   11136 C CB  . LYS D 1 31  ? 8.113   73.432  31.523 1.00 87.60  ? 39  LYS D CB  1 
ATOM   11137 C CG  . LYS D 1 31  ? 9.283   72.882  32.319 1.00 84.68  ? 39  LYS D CG  1 
ATOM   11138 C CD  . LYS D 1 31  ? 8.979   71.511  32.924 1.00 81.80  ? 39  LYS D CD  1 
ATOM   11139 C CE  . LYS D 1 31  ? 9.351   71.429  34.408 1.00 93.10  ? 39  LYS D CE  1 
ATOM   11140 N NZ  . LYS D 1 31  ? 8.623   70.502  35.300 1.00 88.67  ? 39  LYS D NZ  1 
ATOM   11141 N N   . GLU D 1 32  ? 5.709   75.380  30.740 1.00 113.33 ? 40  GLU D N   1 
ATOM   11142 C CA  . GLU D 1 32  ? 4.460   75.501  29.993 1.00 118.25 ? 40  GLU D CA  1 
ATOM   11143 C C   . GLU D 1 32  ? 4.519   76.748  29.102 1.00 122.20 ? 40  GLU D C   1 
ATOM   11144 O O   . GLU D 1 32  ? 4.053   76.755  27.944 1.00 105.48 ? 40  GLU D O   1 
ATOM   11145 C CB  . GLU D 1 32  ? 3.297   75.586  30.983 1.00 95.35  ? 40  GLU D CB  1 
ATOM   11146 C CG  . GLU D 1 32  ? 1.964   75.942  30.334 1.00 92.01  ? 40  GLU D CG  1 
ATOM   11147 C CD  . GLU D 1 32  ? 1.487   74.944  29.289 1.00 123.83 ? 40  GLU D CD  1 
ATOM   11148 O OE1 . GLU D 1 32  ? 1.997   73.789  29.122 1.00 135.63 ? 40  GLU D OE1 1 
ATOM   11149 O OE2 . GLU D 1 32  ? 0.556   75.401  28.593 1.00 112.44 ? 40  GLU D OE2 1 
ATOM   11150 N N   . SER D 1 33  ? 5.088   77.819  29.688 1.00 86.60  ? 41  SER D N   1 
ATOM   11151 C CA  . SER D 1 33  ? 5.246   79.046  28.938 1.00 85.47  ? 41  SER D CA  1 
ATOM   11152 C C   . SER D 1 33  ? 6.085   78.813  27.678 1.00 109.76 ? 41  SER D C   1 
ATOM   11153 O O   . SER D 1 33  ? 5.806   79.362  26.591 1.00 73.92  ? 41  SER D O   1 
ATOM   11154 C CB  . SER D 1 33  ? 5.840   80.108  29.770 1.00 65.22  ? 41  SER D CB  1 
ATOM   11155 O OG  . SER D 1 33  ? 5.704   81.295  28.979 1.00 64.17  ? 41  SER D OG  1 
ATOM   11156 N N   . ASN D 1 34  ? 7.126   77.978  27.853 1.00 104.03 ? 42  ASN D N   1 
ATOM   11157 C CA  . ASN D 1 34  ? 8.014   77.637  26.758 1.00 101.14 ? 42  ASN D CA  1 
ATOM   11158 C C   . ASN D 1 34  ? 7.220   76.850  25.718 1.00 94.04  ? 42  ASN D C   1 
ATOM   11159 O O   . ASN D 1 34  ? 7.356   77.103  24.514 1.00 95.41  ? 42  ASN D O   1 
ATOM   11160 C CB  . ASN D 1 34  ? 9.315   77.010  27.251 1.00 77.55  ? 42  ASN D CB  1 
ATOM   11161 C CG  . ASN D 1 34  ? 10.058  76.357  26.112 1.00 100.50 ? 42  ASN D CG  1 
ATOM   11162 O OD1 . ASN D 1 34  ? 10.561  77.036  25.199 1.00 85.68  ? 42  ASN D OD1 1 
ATOM   11163 N ND2 . ASN D 1 34  ? 10.059  75.031  26.117 1.00 119.81 ? 42  ASN D ND2 1 
ATOM   11164 N N   . ARG D 1 35  ? 6.425   75.889  26.208 1.00 80.82  ? 43  ARG D N   1 
ATOM   11165 C CA  . ARG D 1 35  ? 5.638   75.040  25.326 1.00 94.87  ? 43  ARG D CA  1 
ATOM   11166 C C   . ARG D 1 35  ? 4.756   75.929  24.437 1.00 87.49  ? 43  ARG D C   1 
ATOM   11167 O O   . ARG D 1 35  ? 4.660   75.678  23.225 1.00 64.51  ? 43  ARG D O   1 
ATOM   11168 C CB  . ARG D 1 35  ? 4.842   73.934  26.044 1.00 74.37  ? 43  ARG D CB  1 
ATOM   11169 C CG  . ARG D 1 35  ? 3.764   73.369  25.108 1.00 49.90  ? 43  ARG D CG  1 
ATOM   11170 C CD  . ARG D 1 35  ? 2.600   72.908  25.997 1.00 61.93  ? 43  ARG D CD  1 
ATOM   11171 N NE  . ARG D 1 35  ? 1.323   72.994  25.284 1.00 88.88  ? 43  ARG D NE  1 
ATOM   11172 C CZ  . ARG D 1 35  ? 0.426   73.987  25.392 1.00 116.51 ? 43  ARG D CZ  1 
ATOM   11173 N NH1 . ARG D 1 35  ? 0.771   75.054  26.061 1.00 148.75 ? 43  ARG D NH1 1 
ATOM   11174 N NH2 . ARG D 1 35  ? -0.780  73.972  24.833 1.00 121.59 ? 43  ARG D NH2 1 
ATOM   11175 N N   . GLN D 1 36  ? 4.116   76.940  25.064 1.00 81.41  ? 44  GLN D N   1 
ATOM   11176 C CA  . GLN D 1 36  ? 3.169   77.818  24.388 1.00 92.97  ? 44  GLN D CA  1 
ATOM   11177 C C   . GLN D 1 36  ? 3.926   78.589  23.311 1.00 103.80 ? 44  GLN D C   1 
ATOM   11178 O O   . GLN D 1 36  ? 3.344   78.916  22.268 1.00 119.58 ? 44  GLN D O   1 
ATOM   11179 C CB  . GLN D 1 36  ? 2.369   78.768  25.293 1.00 91.02  ? 44  GLN D CB  1 
ATOM   11180 C CG  . GLN D 1 36  ? 1.350   78.114  26.219 1.00 101.74 ? 44  GLN D CG  1 
ATOM   11181 C CD  . GLN D 1 36  ? 0.881   78.945  27.395 1.00 120.49 ? 44  GLN D CD  1 
ATOM   11182 O OE1 . GLN D 1 36  ? 0.672   80.166  27.310 1.00 114.35 ? 44  GLN D OE1 1 
ATOM   11183 N NE2 . GLN D 1 36  ? 0.693   78.281  28.529 1.00 131.37 ? 44  GLN D NE2 1 
ATOM   11184 N N   . ARG D 1 37  ? 5.196   78.938  23.617 1.00 86.89  ? 45  ARG D N   1 
ATOM   11185 C CA  . ARG D 1 37  ? 5.997   79.801  22.753 1.00 84.12  ? 45  ARG D CA  1 
ATOM   11186 C C   . ARG D 1 37  ? 6.372   79.069  21.461 1.00 105.85 ? 45  ARG D C   1 
ATOM   11187 O O   . ARG D 1 37  ? 6.299   79.639  20.370 1.00 92.41  ? 45  ARG D O   1 
ATOM   11188 C CB  . ARG D 1 37  ? 7.247   80.295  23.477 1.00 82.63  ? 45  ARG D CB  1 
ATOM   11189 C CG  . ARG D 1 37  ? 7.947   81.466  22.774 1.00 64.84  ? 45  ARG D CG  1 
ATOM   11190 C CD  . ARG D 1 37  ? 8.973   82.250  23.647 1.00 67.69  ? 45  ARG D CD  1 
ATOM   11191 N NE  . ARG D 1 37  ? 9.986   81.271  24.081 1.00 91.36  ? 45  ARG D NE  1 
ATOM   11192 C CZ  . ARG D 1 37  ? 10.615  80.392  23.235 1.00 130.01 ? 45  ARG D CZ  1 
ATOM   11193 N NH1 . ARG D 1 37  ? 11.201  79.287  23.674 1.00 98.82  ? 45  ARG D NH1 1 
ATOM   11194 N NH2 . ARG D 1 37  ? 10.579  80.538  21.912 1.00 160.07 ? 45  ARG D NH2 1 
ATOM   11195 N N   . VAL D 1 38  ? 6.828   77.816  21.581 1.00 113.59 ? 46  VAL D N   1 
ATOM   11196 C CA  . VAL D 1 38  ? 7.408   77.123  20.437 1.00 108.65 ? 46  VAL D CA  1 
ATOM   11197 C C   . VAL D 1 38  ? 6.371   76.371  19.609 1.00 110.22 ? 46  VAL D C   1 
ATOM   11198 O O   . VAL D 1 38  ? 6.701   75.934  18.506 1.00 137.53 ? 46  VAL D O   1 
ATOM   11199 C CB  . VAL D 1 38  ? 8.525   76.172  20.871 1.00 97.30  ? 46  VAL D CB  1 
ATOM   11200 C CG1 . VAL D 1 38  ? 9.554   76.931  21.731 1.00 79.63  ? 46  VAL D CG1 1 
ATOM   11201 C CG2 . VAL D 1 38  ? 7.905   74.969  21.575 1.00 102.57 ? 46  VAL D CG2 1 
ATOM   11202 N N   . GLY D 1 39  ? 5.137   76.245  20.110 1.00 98.37  ? 47  GLY D N   1 
ATOM   11203 C CA  . GLY D 1 39  ? 4.098   75.528  19.388 1.00 94.20  ? 47  GLY D CA  1 
ATOM   11204 C C   . GLY D 1 39  ? 3.225   76.447  18.530 1.00 93.54  ? 47  GLY D C   1 
ATOM   11205 O O   . GLY D 1 39  ? 3.087   77.651  18.763 1.00 89.96  ? 47  GLY D O   1 
ATOM   11206 N N   . LEU D 1 40  ? 2.633   75.839  17.503 1.00 88.44  ? 48  LEU D N   1 
ATOM   11207 C CA  . LEU D 1 40  ? 1.689   76.516  16.645 1.00 95.53  ? 48  LEU D CA  1 
ATOM   11208 C C   . LEU D 1 40  ? 0.270   76.170  17.070 1.00 102.61 ? 48  LEU D C   1 
ATOM   11209 O O   . LEU D 1 40  ? -0.211  75.061  16.818 1.00 81.42  ? 48  LEU D O   1 
ATOM   11210 C CB  . LEU D 1 40  ? 1.940   76.083  15.203 1.00 104.02 ? 48  LEU D CB  1 
ATOM   11211 C CG  . LEU D 1 40  ? 3.168   76.694  14.541 1.00 82.93  ? 48  LEU D CG  1 
ATOM   11212 C CD1 . LEU D 1 40  ? 3.259   76.015  13.186 1.00 73.26  ? 48  LEU D CD1 1 
ATOM   11213 C CD2 . LEU D 1 40  ? 2.847   78.180  14.468 1.00 80.62  ? 48  LEU D CD2 1 
ATOM   11214 N N   . GLU D 1 41  ? -0.376  77.160  17.693 1.00 100.52 ? 49  GLU D N   1 
ATOM   11215 C CA  . GLU D 1 41  ? -1.691  77.014  18.294 1.00 76.45  ? 49  GLU D CA  1 
ATOM   11216 C C   . GLU D 1 41  ? -2.839  77.207  17.291 1.00 80.37  ? 49  GLU D C   1 
ATOM   11217 O O   . GLU D 1 41  ? -3.200  78.324  16.885 1.00 74.97  ? 49  GLU D O   1 
ATOM   11218 C CB  . GLU D 1 41  ? -1.726  77.912  19.521 1.00 49.31  ? 49  GLU D CB  1 
ATOM   11219 C CG  . GLU D 1 41  ? -2.756  77.403  20.510 1.00 84.41  ? 49  GLU D CG  1 
ATOM   11220 C CD  . GLU D 1 41  ? -2.548  76.025  21.109 1.00 99.88  ? 49  GLU D CD  1 
ATOM   11221 O OE1 . GLU D 1 41  ? -1.465  75.758  21.670 1.00 80.14  ? 49  GLU D OE1 1 
ATOM   11222 O OE2 . GLU D 1 41  ? -3.495  75.238  20.982 1.00 88.38  ? 49  GLU D OE2 1 
ATOM   11223 N N   . LEU D 1 42  ? -3.489  76.086  16.971 1.00 89.41  ? 50  LEU D N   1 
ATOM   11224 C CA  . LEU D 1 42  ? -4.687  76.114  16.132 1.00 85.75  ? 50  LEU D CA  1 
ATOM   11225 C C   . LEU D 1 42  ? -5.920  75.608  16.885 1.00 119.37 ? 50  LEU D C   1 
ATOM   11226 O O   . LEU D 1 42  ? -6.976  75.461  16.254 1.00 110.74 ? 50  LEU D O   1 
ATOM   11227 C CB  . LEU D 1 42  ? -4.518  75.295  14.862 1.00 58.26  ? 50  LEU D CB  1 
ATOM   11228 C CG  . LEU D 1 42  ? -3.601  75.929  13.827 1.00 74.76  ? 50  LEU D CG  1 
ATOM   11229 C CD1 . LEU D 1 42  ? -2.455  74.958  13.588 1.00 78.74  ? 50  LEU D CD1 1 
ATOM   11230 C CD2 . LEU D 1 42  ? -4.390  76.238  12.547 1.00 91.73  ? 50  LEU D CD2 1 
ATOM   11231 N N   . ILE D 1 43  ? -5.812  75.376  18.207 1.00 106.21 ? 51  ILE D N   1 
ATOM   11232 C CA  . ILE D 1 43  ? -7.035  75.068  18.937 1.00 96.38  ? 51  ILE D CA  1 
ATOM   11233 C C   . ILE D 1 43  ? -7.929  76.315  19.043 1.00 112.34 ? 51  ILE D C   1 
ATOM   11234 O O   . ILE D 1 43  ? -7.611  77.299  19.720 1.00 107.10 ? 51  ILE D O   1 
ATOM   11235 C CB  . ILE D 1 43  ? -6.711  74.538  20.327 1.00 79.10  ? 51  ILE D CB  1 
ATOM   11236 C CG1 . ILE D 1 43  ? -5.745  73.402  20.329 1.00 81.84  ? 51  ILE D CG1 1 
ATOM   11237 C CG2 . ILE D 1 43  ? -8.012  74.234  21.059 1.00 79.22  ? 51  ILE D CG2 1 
ATOM   11238 C CD1 . ILE D 1 43  ? -5.331  73.017  21.740 1.00 136.99 ? 51  ILE D CD1 1 
ATOM   11239 N N   . ALA D 1 44  ? -9.102  76.253  18.411 1.00 98.19  ? 52  ALA D N   1 
ATOM   11240 C CA  . ALA D 1 44  ? -9.990  77.403  18.332 1.00 101.09 ? 52  ALA D CA  1 
ATOM   11241 C C   . ALA D 1 44  ? -10.411 78.002  19.698 1.00 105.86 ? 52  ALA D C   1 
ATOM   11242 O O   . ALA D 1 44  ? -10.860 79.165  19.758 1.00 101.43 ? 52  ALA D O   1 
ATOM   11243 C CB  . ALA D 1 44  ? -11.191 77.004  17.513 1.00 118.44 ? 52  ALA D CB  1 
ATOM   11244 N N   . SER D 1 45  ? -10.298 77.234  20.809 1.00 78.53  ? 53  SER D N   1 
ATOM   11245 C CA  . SER D 1 45  ? -10.748 77.717  22.107 1.00 73.22  ? 53  SER D CA  1 
ATOM   11246 C C   . SER D 1 45  ? -9.640  78.413  22.903 1.00 87.96  ? 53  SER D C   1 
ATOM   11247 O O   . SER D 1 45  ? -9.881  78.978  23.996 1.00 72.87  ? 53  SER D O   1 
ATOM   11248 C CB  . SER D 1 45  ? -11.408 76.623  22.915 1.00 73.93  ? 53  SER D CB  1 
ATOM   11249 O OG  . SER D 1 45  ? -10.528 75.547  23.241 1.00 61.05  ? 53  SER D OG  1 
ATOM   11250 N N   . GLU D 1 46  ? -8.424  78.379  22.328 1.00 100.20 ? 54  GLU D N   1 
ATOM   11251 C CA  . GLU D 1 46  ? -7.256  78.939  22.988 1.00 98.44  ? 54  GLU D CA  1 
ATOM   11252 C C   . GLU D 1 46  ? -7.029  80.373  22.520 1.00 96.93  ? 54  GLU D C   1 
ATOM   11253 O O   . GLU D 1 46  ? -7.475  80.800  21.443 1.00 78.49  ? 54  GLU D O   1 
ATOM   11254 C CB  . GLU D 1 46  ? -6.048  78.066  22.685 1.00 88.11  ? 54  GLU D CB  1 
ATOM   11255 C CG  . GLU D 1 46  ? -6.166  76.668  23.276 1.00 124.65 ? 54  GLU D CG  1 
ATOM   11256 C CD  . GLU D 1 46  ? -5.539  76.560  24.633 1.00 140.18 ? 54  GLU D CD  1 
ATOM   11257 O OE1 . GLU D 1 46  ? -6.023  77.317  25.516 1.00 137.13 ? 54  GLU D OE1 1 
ATOM   11258 O OE2 . GLU D 1 46  ? -4.578  75.735  24.743 1.00 127.95 ? 54  GLU D OE2 1 
ATOM   11259 N N   . ASN D 1 47  ? -6.334  81.095  23.401 1.00 101.29 ? 55  ASN D N   1 
ATOM   11260 C CA  . ASN D 1 47  ? -5.856  82.445  23.170 1.00 80.74  ? 55  ASN D CA  1 
ATOM   11261 C C   . ASN D 1 47  ? -4.814  82.725  24.242 1.00 79.05  ? 55  ASN D C   1 
ATOM   11262 O O   . ASN D 1 47  ? -4.648  81.912  25.154 1.00 112.30 ? 55  ASN D O   1 
ATOM   11263 C CB  . ASN D 1 47  ? -6.975  83.484  23.262 1.00 103.78 ? 55  ASN D CB  1 
ATOM   11264 C CG  . ASN D 1 47  ? -6.840  84.557  22.222 1.00 123.72 ? 55  ASN D CG  1 
ATOM   11265 O OD1 . ASN D 1 47  ? -5.722  85.001  21.948 1.00 114.07 ? 55  ASN D OD1 1 
ATOM   11266 N ND2 . ASN D 1 47  ? -7.956  84.922  21.603 1.00 177.08 ? 55  ASN D ND2 1 
ATOM   11267 N N   . PHE D 1 48  ? -4.132  83.873  24.125 1.00 81.94  ? 56  PHE D N   1 
ATOM   11268 C CA  . PHE D 1 48  ? -3.134  84.262  25.121 1.00 99.38  ? 56  PHE D CA  1 
ATOM   11269 C C   . PHE D 1 48  ? -3.599  85.560  25.779 1.00 125.72 ? 56  PHE D C   1 
ATOM   11270 O O   . PHE D 1 48  ? -3.861  86.546  25.088 1.00 137.84 ? 56  PHE D O   1 
ATOM   11271 C CB  . PHE D 1 48  ? -1.700  84.356  24.588 1.00 79.90  ? 56  PHE D CB  1 
ATOM   11272 C CG  . PHE D 1 48  ? -1.261  83.116  23.816 1.00 93.72  ? 56  PHE D CG  1 
ATOM   11273 C CD1 . PHE D 1 48  ? -0.657  82.077  24.511 1.00 80.80  ? 56  PHE D CD1 1 
ATOM   11274 C CD2 . PHE D 1 48  ? -1.388  82.993  22.412 1.00 94.47  ? 56  PHE D CD2 1 
ATOM   11275 C CE1 . PHE D 1 48  ? -0.188  80.932  23.852 1.00 86.77  ? 56  PHE D CE1 1 
ATOM   11276 C CE2 . PHE D 1 48  ? -0.979  81.835  21.752 1.00 77.08  ? 56  PHE D CE2 1 
ATOM   11277 C CZ  . PHE D 1 48  ? -0.349  80.811  22.484 1.00 90.60  ? 56  PHE D CZ  1 
ATOM   11278 N N   . ALA D 1 49  ? -3.763  85.522  27.103 1.00 117.15 ? 57  ALA D N   1 
ATOM   11279 C CA  . ALA D 1 49  ? -4.211  86.686  27.853 1.00 112.47 ? 57  ALA D CA  1 
ATOM   11280 C C   . ALA D 1 49  ? -3.060  87.688  27.990 1.00 107.44 ? 57  ALA D C   1 
ATOM   11281 O O   . ALA D 1 49  ? -1.907  87.290  28.195 1.00 72.19  ? 57  ALA D O   1 
ATOM   11282 C CB  . ALA D 1 49  ? -4.728  86.241  29.205 1.00 122.57 ? 57  ALA D CB  1 
ATOM   11283 N N   . SER D 1 50  ? -3.404  88.983  27.892 1.00 97.76  ? 58  SER D N   1 
ATOM   11284 C CA  . SER D 1 50  ? -2.493  90.113  28.059 1.00 101.84 ? 58  SER D CA  1 
ATOM   11285 C C   . SER D 1 50  ? -1.848  90.187  29.459 1.00 80.06  ? 58  SER D C   1 
ATOM   11286 O O   . SER D 1 50  ? -2.387  89.635  30.439 1.00 86.46  ? 58  SER D O   1 
ATOM   11287 C CB  . SER D 1 50  ? -3.265  91.364  27.767 1.00 124.84 ? 58  SER D CB  1 
ATOM   11288 O OG  . SER D 1 50  ? -4.262  91.563  28.763 1.00 140.23 ? 58  SER D OG  1 
ATOM   11289 N N   . ARG D 1 51  ? -0.717  90.901  29.573 1.00 54.53  ? 59  ARG D N   1 
ATOM   11290 C CA  . ARG D 1 51  ? -0.012  90.910  30.859 1.00 75.08  ? 59  ARG D CA  1 
ATOM   11291 C C   . ARG D 1 51  ? -0.919  91.557  31.894 1.00 89.66  ? 59  ARG D C   1 
ATOM   11292 O O   . ARG D 1 51  ? -0.970  91.152  33.074 1.00 48.42  ? 59  ARG D O   1 
ATOM   11293 C CB  . ARG D 1 51  ? 0.946   92.029  31.301 1.00 64.80  ? 59  ARG D CB  1 
ATOM   11294 C CG  . ARG D 1 51  ? 2.358   91.991  30.757 1.00 84.03  ? 59  ARG D CG  1 
ATOM   11295 C CD  . ARG D 1 51  ? 3.264   92.737  31.683 1.00 89.89  ? 59  ARG D CD  1 
ATOM   11296 N NE  . ARG D 1 51  ? 3.585   91.794  32.760 1.00 115.76 ? 59  ARG D NE  1 
ATOM   11297 C CZ  . ARG D 1 51  ? 4.263   92.087  33.867 1.00 110.78 ? 59  ARG D CZ  1 
ATOM   11298 N NH1 . ARG D 1 51  ? 4.121   91.306  34.932 1.00 69.26  ? 59  ARG D NH1 1 
ATOM   11299 N NH2 . ARG D 1 51  ? 4.946   93.223  33.947 1.00 123.67 ? 59  ARG D NH2 1 
ATOM   11300 N N   . ALA D 1 52  ? -1.630  92.585  31.396 1.00 114.58 ? 60  ALA D N   1 
ATOM   11301 C CA  . ALA D 1 52  ? -2.478  93.370  32.278 1.00 115.69 ? 60  ALA D CA  1 
ATOM   11302 C C   . ALA D 1 52  ? -3.415  92.411  33.022 1.00 101.48 ? 60  ALA D C   1 
ATOM   11303 O O   . ALA D 1 52  ? -3.503  92.469  34.248 1.00 93.29  ? 60  ALA D O   1 
ATOM   11304 C CB  . ALA D 1 52  ? -3.156  94.462  31.460 1.00 94.25  ? 60  ALA D CB  1 
ATOM   11305 N N   . VAL D 1 53  ? -4.058  91.498  32.264 1.00 95.76  ? 61  VAL D N   1 
ATOM   11306 C CA  . VAL D 1 53  ? -5.056  90.577  32.785 1.00 71.54  ? 61  VAL D CA  1 
ATOM   11307 C C   . VAL D 1 53  ? -4.422  89.664  33.814 1.00 83.12  ? 61  VAL D C   1 
ATOM   11308 O O   . VAL D 1 53  ? -4.921  89.594  34.945 1.00 83.88  ? 61  VAL D O   1 
ATOM   11309 C CB  . VAL D 1 53  ? -5.700  89.733  31.684 1.00 71.14  ? 61  VAL D CB  1 
ATOM   11310 C CG1 . VAL D 1 53  ? -6.556  88.642  32.313 1.00 59.16  ? 61  VAL D CG1 1 
ATOM   11311 C CG2 . VAL D 1 53  ? -6.510  90.600  30.721 1.00 94.67  ? 61  VAL D CG2 1 
ATOM   11312 N N   . LEU D 1 54  ? -3.311  89.019  33.420 1.00 82.50  ? 62  LEU D N   1 
ATOM   11313 C CA  . LEU D 1 54  ? -2.613  88.133  34.344 1.00 74.43  ? 62  LEU D CA  1 
ATOM   11314 C C   . LEU D 1 54  ? -2.248  88.901  35.624 1.00 79.48  ? 62  LEU D C   1 
ATOM   11315 O O   . LEU D 1 54  ? -2.340  88.360  36.741 1.00 58.95  ? 62  LEU D O   1 
ATOM   11316 C CB  . LEU D 1 54  ? -1.379  87.445  33.758 1.00 43.91  ? 62  LEU D CB  1 
ATOM   11317 C CG  . LEU D 1 54  ? -1.559  86.817  32.384 1.00 59.71  ? 62  LEU D CG  1 
ATOM   11318 C CD1 . LEU D 1 54  ? -0.161  86.535  31.859 1.00 86.06  ? 62  LEU D CD1 1 
ATOM   11319 C CD2 . LEU D 1 54  ? -2.375  85.540  32.436 1.00 74.96  ? 62  LEU D CD2 1 
ATOM   11320 N N   . GLU D 1 55  ? -1.826  90.170  35.452 1.00 75.53  ? 63  GLU D N   1 
ATOM   11321 C CA  . GLU D 1 55  ? -1.397  90.943  36.602 1.00 88.26  ? 63  GLU D CA  1 
ATOM   11322 C C   . GLU D 1 55  ? -2.542  91.088  37.602 1.00 96.51  ? 63  GLU D C   1 
ATOM   11323 O O   . GLU D 1 55  ? -2.325  90.999  38.805 1.00 114.91 ? 63  GLU D O   1 
ATOM   11324 C CB  . GLU D 1 55  ? -0.808  92.284  36.176 1.00 93.87  ? 63  GLU D CB  1 
ATOM   11325 C CG  . GLU D 1 55  ? 0.688   92.216  35.873 1.00 71.39  ? 63  GLU D CG  1 
ATOM   11326 C CD  . GLU D 1 55  ? 1.235   93.605  35.563 1.00 88.34  ? 63  GLU D CD  1 
ATOM   11327 O OE1 . GLU D 1 55  ? 0.856   94.212  34.526 1.00 107.06 ? 63  GLU D OE1 1 
ATOM   11328 O OE2 . GLU D 1 55  ? 2.116   94.072  36.294 1.00 77.39  ? 63  GLU D OE2 1 
ATOM   11329 N N   . ALA D 1 56  ? -3.754  91.318  37.097 1.00 88.54  ? 64  ALA D N   1 
ATOM   11330 C CA  . ALA D 1 56  ? -4.929  91.451  37.928 1.00 83.08  ? 64  ALA D CA  1 
ATOM   11331 C C   . ALA D 1 56  ? -5.280  90.160  38.670 1.00 107.87 ? 64  ALA D C   1 
ATOM   11332 O O   . ALA D 1 56  ? -5.624  90.252  39.848 1.00 139.13 ? 64  ALA D O   1 
ATOM   11333 C CB  . ALA D 1 56  ? -6.028  91.907  37.058 1.00 72.32  ? 64  ALA D CB  1 
ATOM   11334 N N   . LEU D 1 57  ? -5.163  88.976  38.039 1.00 101.44 ? 65  LEU D N   1 
ATOM   11335 C CA  . LEU D 1 57  ? -5.394  87.677  38.695 1.00 90.39  ? 65  LEU D CA  1 
ATOM   11336 C C   . LEU D 1 57  ? -4.483  87.466  39.905 1.00 108.83 ? 65  LEU D C   1 
ATOM   11337 O O   . LEU D 1 57  ? -4.878  86.793  40.851 1.00 129.36 ? 65  LEU D O   1 
ATOM   11338 C CB  . LEU D 1 57  ? -5.066  86.528  37.758 1.00 78.15  ? 65  LEU D CB  1 
ATOM   11339 C CG  . LEU D 1 57  ? -6.094  86.237  36.684 1.00 62.27  ? 65  LEU D CG  1 
ATOM   11340 C CD1 . LEU D 1 57  ? -5.407  85.149  35.869 1.00 54.68  ? 65  LEU D CD1 1 
ATOM   11341 C CD2 . LEU D 1 57  ? -7.341  85.771  37.412 1.00 53.97  ? 65  LEU D CD2 1 
ATOM   11342 N N   . GLY D 1 58  ? -3.255  88.001  39.841 1.00 114.47 ? 66  GLY D N   1 
ATOM   11343 C CA  . GLY D 1 58  ? -2.258  87.875  40.886 1.00 99.21  ? 66  GLY D CA  1 
ATOM   11344 C C   . GLY D 1 58  ? -2.462  88.882  42.009 1.00 110.70 ? 66  GLY D C   1 
ATOM   11345 O O   . GLY D 1 58  ? -1.545  89.015  42.815 1.00 170.72 ? 66  GLY D O   1 
ATOM   11346 N N   . SER D 1 59  ? -3.560  89.652  42.029 1.00 97.42  ? 67  SER D N   1 
ATOM   11347 C CA  . SER D 1 59  ? -3.763  90.678  43.059 1.00 117.70 ? 67  SER D CA  1 
ATOM   11348 C C   . SER D 1 59  ? -4.334  90.111  44.361 1.00 99.94  ? 67  SER D C   1 
ATOM   11349 O O   . SER D 1 59  ? -4.829  88.967  44.406 1.00 87.39  ? 67  SER D O   1 
ATOM   11350 C CB  . SER D 1 59  ? -4.614  91.815  42.559 1.00 124.07 ? 67  SER D CB  1 
ATOM   11351 O OG  . SER D 1 59  ? -5.892  91.297  42.231 1.00 83.06  ? 67  SER D OG  1 
ATOM   11352 N N   . CYS D 1 60  ? -4.313  90.979  45.397 1.00 70.71  ? 68  CYS D N   1 
ATOM   11353 C CA  . CYS D 1 60  ? -4.869  90.663  46.721 1.00 86.40  ? 68  CYS D CA  1 
ATOM   11354 C C   . CYS D 1 60  ? -6.399  90.582  46.701 1.00 83.92  ? 68  CYS D C   1 
ATOM   11355 O O   . CYS D 1 60  ? -7.013  90.286  47.725 1.00 73.47  ? 68  CYS D O   1 
ATOM   11356 C CB  . CYS D 1 60  ? -4.545  91.725  47.761 1.00 78.64  ? 68  CYS D CB  1 
ATOM   11357 S SG  . CYS D 1 60  ? -4.980  93.366  47.139 1.00 112.95 ? 68  CYS D SG  1 
ATOM   11358 N N   . LEU D 1 61  ? -7.013  90.846  45.536 1.00 80.57  ? 69  LEU D N   1 
ATOM   11359 C CA  . LEU D 1 61  ? -8.462  90.765  45.361 1.00 75.52  ? 69  LEU D CA  1 
ATOM   11360 C C   . LEU D 1 61  ? -8.892  89.328  45.665 1.00 101.61 ? 69  LEU D C   1 
ATOM   11361 O O   . LEU D 1 61  ? -10.066 89.043  45.948 1.00 88.31  ? 69  LEU D O   1 
ATOM   11362 C CB  . LEU D 1 61  ? -8.851  91.169  43.932 1.00 66.28  ? 69  LEU D CB  1 
ATOM   11363 C CG  . LEU D 1 61  ? -8.587  92.630  43.550 1.00 69.03  ? 69  LEU D CG  1 
ATOM   11364 C CD1 . LEU D 1 61  ? -8.899  92.934  42.117 1.00 65.03  ? 69  LEU D CD1 1 
ATOM   11365 C CD2 . LEU D 1 61  ? -9.438  93.489  44.418 1.00 90.17  ? 69  LEU D CD2 1 
ATOM   11366 N N   . ASN D 1 62  ? -7.911  88.414  45.571 1.00 113.50 ? 70  ASN D N   1 
ATOM   11367 C CA  . ASN D 1 62  ? -8.123  87.006  45.827 1.00 101.01 ? 70  ASN D CA  1 
ATOM   11368 C C   . ASN D 1 62  ? -8.736  86.814  47.209 1.00 107.68 ? 70  ASN D C   1 
ATOM   11369 O O   . ASN D 1 62  ? -9.504  85.883  47.424 1.00 113.17 ? 70  ASN D O   1 
ATOM   11370 C CB  . ASN D 1 62  ? -6.854  86.205  45.567 1.00 86.85  ? 70  ASN D CB  1 
ATOM   11371 C CG  . ASN D 1 62  ? -7.142  84.735  45.763 1.00 133.76 ? 70  ASN D CG  1 
ATOM   11372 O OD1 . ASN D 1 62  ? -6.579  84.075  46.645 1.00 181.48 ? 70  ASN D OD1 1 
ATOM   11373 N ND2 . ASN D 1 62  ? -7.995  84.179  44.921 1.00 135.68 ? 70  ASN D ND2 1 
ATOM   11374 N N   . ASN D 1 63  ? -8.367  87.708  48.132 1.00 110.26 ? 71  ASN D N   1 
ATOM   11375 C CA  . ASN D 1 63  ? -8.506  87.506  49.564 1.00 111.58 ? 71  ASN D CA  1 
ATOM   11376 C C   . ASN D 1 63  ? -9.924  87.797  50.056 1.00 106.65 ? 71  ASN D C   1 
ATOM   11377 O O   . ASN D 1 63  ? -10.394 87.140  50.997 1.00 137.85 ? 71  ASN D O   1 
ATOM   11378 C CB  . ASN D 1 63  ? -7.491  88.335  50.338 1.00 112.82 ? 71  ASN D CB  1 
ATOM   11379 C CG  . ASN D 1 63  ? -6.077  87.873  50.077 1.00 119.94 ? 71  ASN D CG  1 
ATOM   11380 O OD1 . ASN D 1 63  ? -5.830  86.691  49.792 1.00 102.26 ? 71  ASN D OD1 1 
ATOM   11381 N ND2 . ASN D 1 63  ? -5.149  88.814  50.135 1.00 131.17 ? 71  ASN D ND2 1 
ATOM   11382 N N   . LYS D 1 64  ? -10.577 88.763  49.405 1.00 80.55  ? 72  LYS D N   1 
ATOM   11383 C CA  . LYS D 1 64  ? -11.839 89.346  49.847 1.00 97.39  ? 72  LYS D CA  1 
ATOM   11384 C C   . LYS D 1 64  ? -13.067 88.487  49.490 1.00 102.75 ? 72  LYS D C   1 
ATOM   11385 O O   . LYS D 1 64  ? -13.332 88.121  48.320 1.00 99.16  ? 72  LYS D O   1 
ATOM   11386 C CB  . LYS D 1 64  ? -11.978 90.780  49.304 1.00 93.45  ? 72  LYS D CB  1 
ATOM   11387 C CG  . LYS D 1 64  ? -13.178 91.562  49.827 1.00 85.33  ? 72  LYS D CG  1 
ATOM   11388 C CD  . LYS D 1 64  ? -13.115 91.896  51.315 1.00 94.55  ? 72  LYS D CD  1 
ATOM   11389 C CE  . LYS D 1 64  ? -14.378 92.533  51.880 1.00 113.02 ? 72  LYS D CE  1 
ATOM   11390 N NZ  . LYS D 1 64  ? -15.136 91.565  52.684 1.00 126.34 ? 72  LYS D NZ  1 
ATOM   11391 N N   . TYR D 1 65  ? -13.879 88.251  50.536 1.00 79.20  ? 73  TYR D N   1 
ATOM   11392 C CA  . TYR D 1 65  ? -15.189 87.645  50.384 1.00 85.33  ? 73  TYR D CA  1 
ATOM   11393 C C   . TYR D 1 65  ? -16.141 88.770  50.020 1.00 87.40  ? 73  TYR D C   1 
ATOM   11394 O O   . TYR D 1 65  ? -16.258 89.694  50.819 1.00 113.62 ? 73  TYR D O   1 
ATOM   11395 C CB  . TYR D 1 65  ? -15.682 86.919  51.657 1.00 82.86  ? 73  TYR D CB  1 
ATOM   11396 C CG  . TYR D 1 65  ? -15.797 85.418  51.407 1.00 82.63  ? 73  TYR D CG  1 
ATOM   11397 C CD1 . TYR D 1 65  ? -16.821 84.859  50.638 1.00 75.14  ? 73  TYR D CD1 1 
ATOM   11398 C CD2 . TYR D 1 65  ? -14.752 84.579  51.764 1.00 82.55  ? 73  TYR D CD2 1 
ATOM   11399 C CE1 . TYR D 1 65  ? -16.829 83.516  50.286 1.00 71.46  ? 73  TYR D CE1 1 
ATOM   11400 C CE2 . TYR D 1 65  ? -14.755 83.230  51.422 1.00 86.32  ? 73  TYR D CE2 1 
ATOM   11401 C CZ  . TYR D 1 65  ? -15.786 82.687  50.669 1.00 67.50  ? 73  TYR D CZ  1 
ATOM   11402 O OH  . TYR D 1 65  ? -15.753 81.345  50.391 1.00 49.58  ? 73  TYR D OH  1 
ATOM   11403 N N   . SER D 1 66  ? -16.835 88.658  48.873 1.00 79.21  ? 74  SER D N   1 
ATOM   11404 C CA  . SER D 1 66  ? -17.828 89.684  48.586 1.00 82.31  ? 74  SER D CA  1 
ATOM   11405 C C   . SER D 1 66  ? -19.201 89.112  48.223 1.00 76.08  ? 74  SER D C   1 
ATOM   11406 O O   . SER D 1 66  ? -19.786 89.557  47.225 1.00 42.43  ? 74  SER D O   1 
ATOM   11407 C CB  . SER D 1 66  ? -17.341 90.665  47.549 1.00 84.73  ? 74  SER D CB  1 
ATOM   11408 O OG  . SER D 1 66  ? -17.003 89.990  46.345 1.00 94.38  ? 74  SER D OG  1 
ATOM   11409 N N   . GLU D 1 67  ? -19.718 88.189  49.060 1.00 65.47  ? 75  GLU D N   1 
ATOM   11410 C CA  . GLU D 1 67  ? -20.927 87.474  48.711 1.00 95.59  ? 75  GLU D CA  1 
ATOM   11411 C C   . GLU D 1 67  ? -22.086 88.439  48.456 1.00 108.61 ? 75  GLU D C   1 
ATOM   11412 O O   . GLU D 1 67  ? -22.324 89.385  49.216 1.00 85.47  ? 75  GLU D O   1 
ATOM   11413 C CB  . GLU D 1 67  ? -21.235 86.380  49.729 1.00 94.74  ? 75  GLU D CB  1 
ATOM   11414 C CG  . GLU D 1 67  ? -20.585 85.054  49.356 1.00 80.07  ? 75  GLU D CG  1 
ATOM   11415 C CD  . GLU D 1 67  ? -20.748 83.983  50.409 1.00 81.59  ? 75  GLU D CD  1 
ATOM   11416 O OE1 . GLU D 1 67  ? -20.872 84.422  51.581 1.00 62.89  ? 75  GLU D OE1 1 
ATOM   11417 O OE2 . GLU D 1 67  ? -20.764 82.762  50.073 1.00 87.06  ? 75  GLU D OE2 1 
ATOM   11418 N N   . GLY D 1 68  ? -22.810 88.185  47.358 1.00 94.53  ? 76  GLY D N   1 
ATOM   11419 C CA  . GLY D 1 68  ? -23.884 89.099  47.043 1.00 95.74  ? 76  GLY D CA  1 
ATOM   11420 C C   . GLY D 1 68  ? -23.464 89.977  45.877 1.00 96.97  ? 76  GLY D C   1 
ATOM   11421 O O   . GLY D 1 68  ? -22.534 89.616  45.144 1.00 128.02 ? 76  GLY D O   1 
ATOM   11422 N N   . TYR D 1 69  ? -24.139 91.123  45.724 1.00 72.31  ? 77  TYR D N   1 
ATOM   11423 C CA  . TYR D 1 69  ? -23.841 92.023  44.625 1.00 92.41  ? 77  TYR D CA  1 
ATOM   11424 C C   . TYR D 1 69  ? -23.547 93.447  45.112 1.00 103.09 ? 77  TYR D C   1 
ATOM   11425 O O   . TYR D 1 69  ? -23.843 93.780  46.262 1.00 102.58 ? 77  TYR D O   1 
ATOM   11426 C CB  . TYR D 1 69  ? -25.049 91.971  43.705 1.00 84.08  ? 77  TYR D CB  1 
ATOM   11427 C CG  . TYR D 1 69  ? -25.224 90.621  43.039 1.00 72.04  ? 77  TYR D CG  1 
ATOM   11428 C CD1 . TYR D 1 69  ? -24.495 90.272  41.905 1.00 83.71  ? 77  TYR D CD1 1 
ATOM   11429 C CD2 . TYR D 1 69  ? -26.167 89.721  43.512 1.00 82.15  ? 77  TYR D CD2 1 
ATOM   11430 C CE1 . TYR D 1 69  ? -24.683 89.049  41.280 1.00 95.29  ? 77  TYR D CE1 1 
ATOM   11431 C CE2 . TYR D 1 69  ? -26.388 88.504  42.890 1.00 80.47  ? 77  TYR D CE2 1 
ATOM   11432 C CZ  . TYR D 1 69  ? -25.608 88.155  41.801 1.00 101.80 ? 77  TYR D CZ  1 
ATOM   11433 O OH  . TYR D 1 69  ? -25.815 86.928  41.227 1.00 90.95  ? 77  TYR D OH  1 
ATOM   11434 N N   . PRO D 1 70  ? -22.927 94.308  44.276 1.00 88.00  ? 78  PRO D N   1 
ATOM   11435 C CA  . PRO D 1 70  ? -22.591 95.666  44.711 1.00 95.68  ? 78  PRO D CA  1 
ATOM   11436 C C   . PRO D 1 70  ? -23.847 96.363  45.197 1.00 110.90 ? 78  PRO D C   1 
ATOM   11437 O O   . PRO D 1 70  ? -24.835 96.368  44.471 1.00 114.02 ? 78  PRO D O   1 
ATOM   11438 C CB  . PRO D 1 70  ? -22.056 96.285  43.455 1.00 100.61 ? 78  PRO D CB  1 
ATOM   11439 C CG  . PRO D 1 70  ? -21.499 95.124  42.693 1.00 112.22 ? 78  PRO D CG  1 
ATOM   11440 C CD  . PRO D 1 70  ? -22.447 93.967  42.931 1.00 86.73  ? 78  PRO D CD  1 
ATOM   11441 N N   . GLY D 1 71  ? -23.796 96.902  46.427 1.00 122.70 ? 79  GLY D N   1 
ATOM   11442 C CA  . GLY D 1 71  ? -24.933 97.619  46.975 1.00 105.16 ? 79  GLY D CA  1 
ATOM   11443 C C   . GLY D 1 71  ? -25.972 96.681  47.576 1.00 93.24  ? 79  GLY D C   1 
ATOM   11444 O O   . GLY D 1 71  ? -26.899 97.175  48.177 1.00 96.15  ? 79  GLY D O   1 
ATOM   11445 N N   . GLN D 1 72  ? -25.810 95.355  47.422 1.00 97.35  ? 80  GLN D N   1 
ATOM   11446 C CA  . GLN D 1 72  ? -26.460 94.366  48.265 1.00 92.76  ? 80  GLN D CA  1 
ATOM   11447 C C   . GLN D 1 72  ? -25.471 93.284  48.722 1.00 94.17  ? 80  GLN D C   1 
ATOM   11448 O O   . GLN D 1 72  ? -25.639 92.121  48.344 1.00 116.10 ? 80  GLN D O   1 
ATOM   11449 C CB  . GLN D 1 72  ? -27.736 93.811  47.619 1.00 93.32  ? 80  GLN D CB  1 
ATOM   11450 C CG  . GLN D 1 72  ? -29.050 94.317  48.238 1.00 91.42  ? 80  GLN D CG  1 
ATOM   11451 C CD  . GLN D 1 72  ? -29.943 93.206  48.776 1.00 124.79 ? 80  GLN D CD  1 
ATOM   11452 O OE1 . GLN D 1 72  ? -30.091 92.989  49.993 1.00 127.08 ? 80  GLN D OE1 1 
ATOM   11453 N NE2 . GLN D 1 72  ? -30.473 92.435  47.842 1.00 107.42 ? 80  GLN D NE2 1 
ATOM   11454 N N   . ARG D 1 73  ? -24.479 93.657  49.549 1.00 74.09  ? 81  ARG D N   1 
ATOM   11455 C CA  . ARG D 1 73  ? -23.455 92.705  49.980 1.00 72.40  ? 81  ARG D CA  1 
ATOM   11456 C C   . ARG D 1 73  ? -23.859 92.023  51.271 1.00 66.42  ? 81  ARG D C   1 
ATOM   11457 O O   . ARG D 1 73  ? -24.740 92.508  51.961 1.00 131.66 ? 81  ARG D O   1 
ATOM   11458 C CB  . ARG D 1 73  ? -22.062 93.333  50.132 1.00 72.74  ? 81  ARG D CB  1 
ATOM   11459 C CG  . ARG D 1 73  ? -21.417 93.711  48.804 1.00 91.82  ? 81  ARG D CG  1 
ATOM   11460 C CD  . ARG D 1 73  ? -21.236 92.602  47.737 1.00 77.86  ? 81  ARG D CD  1 
ATOM   11461 N NE  . ARG D 1 73  ? -20.409 93.145  46.659 1.00 83.70  ? 81  ARG D NE  1 
ATOM   11462 C CZ  . ARG D 1 73  ? -19.974 92.577  45.535 1.00 110.18 ? 81  ARG D CZ  1 
ATOM   11463 N NH1 . ARG D 1 73  ? -20.299 91.332  45.245 1.00 116.33 ? 81  ARG D NH1 1 
ATOM   11464 N NH2 . ARG D 1 73  ? -19.162 93.271  44.738 1.00 102.78 ? 81  ARG D NH2 1 
ATOM   11465 N N   . TYR D 1 74  ? -23.191 90.916  51.600 1.00 66.04  ? 82  TYR D N   1 
ATOM   11466 C CA  . TYR D 1 74  ? -23.446 90.223  52.863 1.00 64.78  ? 82  TYR D CA  1 
ATOM   11467 C C   . TYR D 1 74  ? -22.142 90.275  53.661 1.00 83.73  ? 82  TYR D C   1 
ATOM   11468 O O   . TYR D 1 74  ? -22.009 89.699  54.739 1.00 62.03  ? 82  TYR D O   1 
ATOM   11469 C CB  . TYR D 1 74  ? -23.908 88.759  52.773 1.00 49.66  ? 82  TYR D CB  1 
ATOM   11470 C CG  . TYR D 1 74  ? -25.166 88.438  51.978 1.00 62.94  ? 82  TYR D CG  1 
ATOM   11471 C CD1 . TYR D 1 74  ? -25.198 88.595  50.577 1.00 87.59  ? 82  TYR D CD1 1 
ATOM   11472 C CD2 . TYR D 1 74  ? -26.335 88.032  52.607 1.00 65.41  ? 82  TYR D CD2 1 
ATOM   11473 C CE1 . TYR D 1 74  ? -26.353 88.385  49.834 1.00 71.35  ? 82  TYR D CE1 1 
ATOM   11474 C CE2 . TYR D 1 74  ? -27.501 87.792  51.878 1.00 69.91  ? 82  TYR D CE2 1 
ATOM   11475 C CZ  . TYR D 1 74  ? -27.503 87.963  50.498 1.00 79.77  ? 82  TYR D CZ  1 
ATOM   11476 O OH  . TYR D 1 74  ? -28.640 87.677  49.810 1.00 76.88  ? 82  TYR D OH  1 
ATOM   11477 N N   . TYR D 1 75  ? -21.097 90.876  53.087 1.00 98.41  ? 83  TYR D N   1 
ATOM   11478 C CA  . TYR D 1 75  ? -19.915 91.192  53.875 1.00 94.05  ? 83  TYR D CA  1 
ATOM   11479 C C   . TYR D 1 75  ? -19.644 92.694  53.807 1.00 109.71 ? 83  TYR D C   1 
ATOM   11480 O O   . TYR D 1 75  ? -20.064 93.356  52.859 1.00 117.73 ? 83  TYR D O   1 
ATOM   11481 C CB  . TYR D 1 75  ? -18.739 90.334  53.409 1.00 87.44  ? 83  TYR D CB  1 
ATOM   11482 C CG  . TYR D 1 75  ? -18.848 88.831  53.617 1.00 126.78 ? 83  TYR D CG  1 
ATOM   11483 C CD1 . TYR D 1 75  ? -18.859 88.250  54.894 1.00 137.23 ? 83  TYR D CD1 1 
ATOM   11484 C CD2 . TYR D 1 75  ? -18.878 87.982  52.518 1.00 132.80 ? 83  TYR D CD2 1 
ATOM   11485 C CE1 . TYR D 1 75  ? -18.927 86.870  55.060 1.00 151.78 ? 83  TYR D CE1 1 
ATOM   11486 C CE2 . TYR D 1 75  ? -18.944 86.602  52.675 1.00 139.90 ? 83  TYR D CE2 1 
ATOM   11487 C CZ  . TYR D 1 75  ? -18.941 86.038  53.943 1.00 157.79 ? 83  TYR D CZ  1 
ATOM   11488 O OH  . TYR D 1 75  ? -18.961 84.663  54.037 1.00 120.52 ? 83  TYR D OH  1 
ATOM   11489 N N   . GLY D 1 76  ? -18.874 93.215  54.782 1.00 103.92 ? 84  GLY D N   1 
ATOM   11490 C CA  . GLY D 1 76  ? -18.402 94.593  54.796 1.00 91.76  ? 84  GLY D CA  1 
ATOM   11491 C C   . GLY D 1 76  ? -17.026 94.807  54.143 1.00 103.94 ? 84  GLY D C   1 
ATOM   11492 O O   . GLY D 1 76  ? -16.240 93.885  53.905 1.00 107.47 ? 84  GLY D O   1 
ATOM   11493 N N   . GLY D 1 77  ? -16.754 96.079  53.817 1.00 94.07  ? 85  GLY D N   1 
ATOM   11494 C CA  . GLY D 1 77  ? -15.482 96.537  53.279 1.00 78.98  ? 85  GLY D CA  1 
ATOM   11495 C C   . GLY D 1 77  ? -15.337 96.183  51.807 1.00 86.34  ? 85  GLY D C   1 
ATOM   11496 O O   . GLY D 1 77  ? -14.233 96.050  51.256 1.00 100.42 ? 85  GLY D O   1 
ATOM   11497 N N   . THR D 1 78  ? -16.492 96.080  51.169 1.00 95.15  ? 86  THR D N   1 
ATOM   11498 C CA  . THR D 1 78  ? -16.528 95.811  49.751 1.00 113.80 ? 86  THR D CA  1 
ATOM   11499 C C   . THR D 1 78  ? -16.594 97.103  48.952 1.00 97.53  ? 86  THR D C   1 
ATOM   11500 O O   . THR D 1 78  ? -16.835 97.023  47.768 1.00 119.23 ? 86  THR D O   1 
ATOM   11501 C CB  . THR D 1 78  ? -17.716 94.896  49.445 1.00 141.00 ? 86  THR D CB  1 
ATOM   11502 O OG1 . THR D 1 78  ? -18.896 95.608  49.786 1.00 130.45 ? 86  THR D OG1 1 
ATOM   11503 C CG2 . THR D 1 78  ? -17.702 93.623  50.271 1.00 163.97 ? 86  THR D CG2 1 
ATOM   11504 N N   . GLU D 1 79  ? -16.319 98.265  49.554 1.00 105.40 ? 87  GLU D N   1 
ATOM   11505 C CA  . GLU D 1 79  ? -16.312 99.510  48.803 1.00 113.67 ? 87  GLU D CA  1 
ATOM   11506 C C   . GLU D 1 79  ? -15.425 99.411  47.552 1.00 113.05 ? 87  GLU D C   1 
ATOM   11507 O O   . GLU D 1 79  ? -15.858 99.887  46.502 1.00 103.86 ? 87  GLU D O   1 
ATOM   11508 C CB  . GLU D 1 79  ? -15.972 100.688 49.725 1.00 107.19 ? 87  GLU D CB  1 
ATOM   11509 C CG  . GLU D 1 79  ? -15.380 101.916 49.021 1.00 103.92 ? 87  GLU D CG  1 
ATOM   11510 C CD  . GLU D 1 79  ? -14.598 102.710 50.071 1.00 106.23 ? 87  GLU D CD  1 
ATOM   11511 O OE1 . GLU D 1 79  ? -14.826 102.295 51.242 1.00 85.45  ? 87  GLU D OE1 1 
ATOM   11512 O OE2 . GLU D 1 79  ? -13.818 103.674 49.815 1.00 85.48  ? 87  GLU D OE2 1 
ATOM   11513 N N   . PHE D 1 80  ? -14.224 98.795  47.649 1.00 84.17  ? 88  PHE D N   1 
ATOM   11514 C CA  . PHE D 1 80  ? -13.350 98.737  46.483 1.00 78.92  ? 88  PHE D CA  1 
ATOM   11515 C C   . PHE D 1 80  ? -13.780 97.606  45.552 1.00 87.51  ? 88  PHE D C   1 
ATOM   11516 O O   . PHE D 1 80  ? -13.697 97.751  44.324 1.00 93.78  ? 88  PHE D O   1 
ATOM   11517 C CB  . PHE D 1 80  ? -11.829 98.719  46.701 1.00 73.61  ? 88  PHE D CB  1 
ATOM   11518 C CG  . PHE D 1 80  ? -11.451 99.883  47.593 1.00 85.93  ? 88  PHE D CG  1 
ATOM   11519 C CD1 . PHE D 1 80  ? -11.628 101.180 47.131 1.00 83.18  ? 88  PHE D CD1 1 
ATOM   11520 C CD2 . PHE D 1 80  ? -11.010 99.680  48.907 1.00 95.73  ? 88  PHE D CD2 1 
ATOM   11521 C CE1 . PHE D 1 80  ? -11.369 102.253 47.969 1.00 79.92  ? 88  PHE D CE1 1 
ATOM   11522 C CE2 . PHE D 1 80  ? -10.762 100.756 49.745 1.00 83.90  ? 88  PHE D CE2 1 
ATOM   11523 C CZ  . PHE D 1 80  ? -10.929 102.035 49.258 1.00 79.37  ? 88  PHE D CZ  1 
ATOM   11524 N N   . ILE D 1 81  ? -14.226 96.489  46.143 1.00 75.46  ? 89  ILE D N   1 
ATOM   11525 C CA  . ILE D 1 81  ? -14.726 95.386  45.333 1.00 76.50  ? 89  ILE D CA  1 
ATOM   11526 C C   . ILE D 1 81  ? -15.919 95.889  44.514 1.00 80.25  ? 89  ILE D C   1 
ATOM   11527 O O   . ILE D 1 81  ? -16.143 95.502  43.368 1.00 78.93  ? 89  ILE D O   1 
ATOM   11528 C CB  . ILE D 1 81  ? -15.111 94.195  46.229 1.00 72.79  ? 89  ILE D CB  1 
ATOM   11529 C CG1 . ILE D 1 81  ? -13.889 93.646  47.024 1.00 93.35  ? 89  ILE D CG1 1 
ATOM   11530 C CG2 . ILE D 1 81  ? -15.895 93.102  45.493 1.00 60.33  ? 89  ILE D CG2 1 
ATOM   11531 C CD1 . ILE D 1 81  ? -12.595 93.420  46.246 1.00 62.67  ? 89  ILE D CD1 1 
ATOM   11532 N N   . ASP D 1 82  ? -16.711 96.757  45.132 1.00 73.05  ? 90  ASP D N   1 
ATOM   11533 C CA  . ASP D 1 82  ? -17.923 97.238  44.517 1.00 70.45  ? 90  ASP D CA  1 
ATOM   11534 C C   . ASP D 1 82  ? -17.539 98.140  43.362 1.00 94.17  ? 90  ASP D C   1 
ATOM   11535 O O   . ASP D 1 82  ? -18.191 98.066  42.329 1.00 96.68  ? 90  ASP D O   1 
ATOM   11536 C CB  . ASP D 1 82  ? -18.803 97.884  45.554 1.00 71.91  ? 90  ASP D CB  1 
ATOM   11537 C CG  . ASP D 1 82  ? -19.468 96.873  46.469 1.00 83.74  ? 90  ASP D CG  1 
ATOM   11538 O OD1 . ASP D 1 82  ? -19.448 95.667  46.154 1.00 83.44  ? 90  ASP D OD1 1 
ATOM   11539 O OD2 . ASP D 1 82  ? -20.099 97.312  47.432 1.00 94.21  ? 90  ASP D OD2 1 
ATOM   11540 N N   . GLU D 1 83  ? -16.480 98.955  43.529 1.00 88.75  ? 91  GLU D N   1 
ATOM   11541 C CA  . GLU D 1 83  ? -16.017 99.782  42.419 1.00 94.66  ? 91  GLU D CA  1 
ATOM   11542 C C   . GLU D 1 83  ? -15.716 98.848  41.256 1.00 103.19 ? 91  GLU D C   1 
ATOM   11543 O O   . GLU D 1 83  ? -16.181 99.063  40.131 1.00 109.57 ? 91  GLU D O   1 
ATOM   11544 C CB  . GLU D 1 83  ? -14.713 100.554 42.616 1.00 82.06  ? 91  GLU D CB  1 
ATOM   11545 C CG  . GLU D 1 83  ? -14.696 101.596 43.734 1.00 114.73 ? 91  GLU D CG  1 
ATOM   11546 C CD  . GLU D 1 83  ? -13.458 102.477 43.534 1.00 116.26 ? 91  GLU D CD  1 
ATOM   11547 O OE1 . GLU D 1 83  ? -12.918 102.433 42.366 1.00 67.58  ? 91  GLU D OE1 1 
ATOM   11548 O OE2 . GLU D 1 83  ? -13.035 103.180 44.525 1.00 103.45 ? 91  GLU D OE2 1 
ATOM   11549 N N   . LEU D 1 84  ? -14.945 97.797  41.584 1.00 84.57  ? 92  LEU D N   1 
ATOM   11550 C CA  . LEU D 1 84  ? -14.421 96.867  40.607 1.00 63.53  ? 92  LEU D CA  1 
ATOM   11551 C C   . LEU D 1 84  ? -15.578 96.188  39.888 1.00 77.73  ? 92  LEU D C   1 
ATOM   11552 O O   . LEU D 1 84  ? -15.643 96.271  38.661 1.00 76.99  ? 92  LEU D O   1 
ATOM   11553 C CB  . LEU D 1 84  ? -13.529 95.852  41.297 1.00 56.11  ? 92  LEU D CB  1 
ATOM   11554 C CG  . LEU D 1 84  ? -13.090 94.685  40.411 1.00 63.90  ? 92  LEU D CG  1 
ATOM   11555 C CD1 . LEU D 1 84  ? -12.269 95.173  39.205 1.00 53.46  ? 92  LEU D CD1 1 
ATOM   11556 C CD2 . LEU D 1 84  ? -12.377 93.632  41.263 1.00 69.52  ? 92  LEU D CD2 1 
ATOM   11557 N N   . GLU D 1 85  ? -16.448 95.495  40.642 1.00 68.05  ? 93  GLU D N   1 
ATOM   11558 C CA  . GLU D 1 85  ? -17.540 94.747  40.025 1.00 85.54  ? 93  GLU D CA  1 
ATOM   11559 C C   . GLU D 1 85  ? -18.416 95.674  39.179 1.00 104.80 ? 93  GLU D C   1 
ATOM   11560 O O   . GLU D 1 85  ? -18.746 95.365  38.039 1.00 115.80 ? 93  GLU D O   1 
ATOM   11561 C CB  . GLU D 1 85  ? -18.383 94.030  41.071 1.00 63.84  ? 93  GLU D CB  1 
ATOM   11562 C CG  . GLU D 1 85  ? -19.422 93.108  40.455 1.00 59.78  ? 93  GLU D CG  1 
ATOM   11563 C CD  . GLU D 1 85  ? -19.842 91.931  41.359 1.00 91.96  ? 93  GLU D CD  1 
ATOM   11564 O OE1 . GLU D 1 85  ? -19.299 91.720  42.508 1.00 77.02  ? 93  GLU D OE1 1 
ATOM   11565 O OE2 . GLU D 1 85  ? -20.807 91.243  40.940 1.00 101.61 ? 93  GLU D OE2 1 
ATOM   11566 N N   . THR D 1 86  ? -18.743 96.848  39.712 1.00 93.99  ? 94  THR D N   1 
ATOM   11567 C CA  . THR D 1 86  ? -19.579 97.778  38.978 1.00 91.08  ? 94  THR D CA  1 
ATOM   11568 C C   . THR D 1 86  ? -18.837 98.218  37.724 1.00 103.15 ? 94  THR D C   1 
ATOM   11569 O O   . THR D 1 86  ? -19.409 98.196  36.638 1.00 103.12 ? 94  THR D O   1 
ATOM   11570 C CB  . THR D 1 86  ? -20.016 98.958  39.842 1.00 80.63  ? 94  THR D CB  1 
ATOM   11571 O OG1 . THR D 1 86  ? -20.789 98.344  40.854 1.00 100.71 ? 94  THR D OG1 1 
ATOM   11572 C CG2 . THR D 1 86  ? -21.256 99.634  39.309 1.00 55.77  ? 94  THR D CG2 1 
ATOM   11573 N N   . LEU D 1 87  ? -17.561 98.588  37.887 1.00 101.79 ? 95  LEU D N   1 
ATOM   11574 C CA  . LEU D 1 87  ? -16.738 98.989  36.754 1.00 76.98  ? 95  LEU D CA  1 
ATOM   11575 C C   . LEU D 1 87  ? -16.810 97.895  35.691 1.00 80.38  ? 95  LEU D C   1 
ATOM   11576 O O   . LEU D 1 87  ? -17.093 98.171  34.528 1.00 68.32  ? 95  LEU D O   1 
ATOM   11577 C CB  . LEU D 1 87  ? -15.286 99.285  37.144 1.00 53.98  ? 95  LEU D CB  1 
ATOM   11578 C CG  . LEU D 1 87  ? -14.378 99.729  35.991 1.00 59.28  ? 95  LEU D CG  1 
ATOM   11579 C CD1 . LEU D 1 87  ? -14.890 100.967 35.194 1.00 70.39  ? 95  LEU D CD1 1 
ATOM   11580 C CD2 . LEU D 1 87  ? -12.996 100.043 36.572 1.00 62.18  ? 95  LEU D CD2 1 
ATOM   11581 N N   . CYS D 1 88  ? -16.583 96.642  36.119 1.00 64.18  ? 96  CYS D N   1 
ATOM   11582 C CA  . CYS D 1 88  ? -16.587 95.522  35.196 1.00 73.35  ? 96  CYS D CA  1 
ATOM   11583 C C   . CYS D 1 88  ? -17.899 95.467  34.399 1.00 76.30  ? 96  CYS D C   1 
ATOM   11584 O O   . CYS D 1 88  ? -17.877 95.375  33.143 1.00 47.98  ? 96  CYS D O   1 
ATOM   11585 C CB  . CYS D 1 88  ? -16.403 94.194  35.913 1.00 52.54  ? 96  CYS D CB  1 
ATOM   11586 S SG  . CYS D 1 88  ? -15.989 92.893  34.721 1.00 65.41  ? 96  CYS D SG  1 
ATOM   11587 N N   . GLN D 1 89  ? -19.031 95.507  35.144 1.00 55.59  ? 97  GLN D N   1 
ATOM   11588 C CA  . GLN D 1 89  ? -20.343 95.393  34.532 1.00 53.12  ? 97  GLN D CA  1 
ATOM   11589 C C   . GLN D 1 89  ? -20.512 96.509  33.487 1.00 76.72  ? 97  GLN D C   1 
ATOM   11590 O O   . GLN D 1 89  ? -21.015 96.269  32.360 1.00 69.42  ? 97  GLN D O   1 
ATOM   11591 C CB  . GLN D 1 89  ? -21.426 95.568  35.600 1.00 49.11  ? 97  GLN D CB  1 
ATOM   11592 C CG  . GLN D 1 89  ? -21.820 94.325  36.372 1.00 58.82  ? 97  GLN D CG  1 
ATOM   11593 C CD  . GLN D 1 89  ? -22.167 94.584  37.834 1.00 65.51  ? 97  GLN D CD  1 
ATOM   11594 O OE1 . GLN D 1 89  ? -22.024 95.697  38.352 1.00 47.25  ? 97  GLN D OE1 1 
ATOM   11595 N NE2 . GLN D 1 89  ? -22.487 93.515  38.563 1.00 81.96  ? 97  GLN D NE2 1 
ATOM   11596 N N   . LYS D 1 90  ? -20.130 97.735  33.916 1.00 72.13  ? 98  LYS D N   1 
ATOM   11597 C CA  . LYS D 1 90  ? -20.285 98.918  33.095 1.00 69.45  ? 98  LYS D CA  1 
ATOM   11598 C C   . LYS D 1 90  ? -19.501 98.716  31.797 1.00 88.42  ? 98  LYS D C   1 
ATOM   11599 O O   . LYS D 1 90  ? -20.045 98.941  30.714 1.00 74.92  ? 98  LYS D O   1 
ATOM   11600 C CB  . LYS D 1 90  ? -19.883 100.141 33.918 1.00 66.55  ? 98  LYS D CB  1 
ATOM   11601 C CG  . LYS D 1 90  ? -19.920 101.460 33.135 1.00 79.38  ? 98  LYS D CG  1 
ATOM   11602 C CD  . LYS D 1 90  ? -19.835 102.687 34.067 1.00 105.51 ? 98  LYS D CD  1 
ATOM   11603 C CE  . LYS D 1 90  ? -18.473 103.044 34.651 1.00 125.03 ? 98  LYS D CE  1 
ATOM   11604 N NZ  . LYS D 1 90  ? -17.588 103.437 33.541 1.00 121.54 ? 98  LYS D NZ  1 
ATOM   11605 N N   . ARG D 1 91  ? -18.234 98.262  31.914 1.00 77.78  ? 99  ARG D N   1 
ATOM   11606 C CA  . ARG D 1 91  ? -17.345 98.089  30.780 1.00 75.53  ? 99  ARG D CA  1 
ATOM   11607 C C   . ARG D 1 91  ? -17.887 97.016  29.845 1.00 83.85  ? 99  ARG D C   1 
ATOM   11608 O O   . ARG D 1 91  ? -17.795 97.139  28.618 1.00 87.03  ? 99  ARG D O   1 
ATOM   11609 C CB  . ARG D 1 91  ? -15.955 97.659  31.244 1.00 75.47  ? 99  ARG D CB  1 
ATOM   11610 C CG  . ARG D 1 91  ? -15.138 98.787  31.842 1.00 87.31  ? 99  ARG D CG  1 
ATOM   11611 C CD  . ARG D 1 91  ? -13.743 98.251  32.158 1.00 88.14  ? 99  ARG D CD  1 
ATOM   11612 N NE  . ARG D 1 91  ? -12.864 99.341  32.580 1.00 77.63  ? 99  ARG D NE  1 
ATOM   11613 C CZ  . ARG D 1 91  ? -11.631 99.167  32.989 1.00 92.33  ? 99  ARG D CZ  1 
ATOM   11614 N NH1 . ARG D 1 91  ? -11.152 97.953  33.120 1.00 98.84  ? 99  ARG D NH1 1 
ATOM   11615 N NH2 . ARG D 1 91  ? -10.878 100.210 33.274 1.00 102.50 ? 99  ARG D NH2 1 
ATOM   11616 N N   . ALA D 1 92  ? -18.439 95.945  30.440 1.00 77.36  ? 100 ALA D N   1 
ATOM   11617 C CA  . ALA D 1 92  ? -18.980 94.884  29.609 1.00 76.38  ? 100 ALA D CA  1 
ATOM   11618 C C   . ALA D 1 92  ? -20.069 95.443  28.683 1.00 78.96  ? 100 ALA D C   1 
ATOM   11619 O O   . ALA D 1 92  ? -19.970 95.279  27.441 1.00 48.83  ? 100 ALA D O   1 
ATOM   11620 C CB  . ALA D 1 92  ? -19.512 93.773  30.465 1.00 70.79  ? 100 ALA D CB  1 
ATOM   11621 N N   . LEU D 1 93  ? -21.043 96.163  29.289 1.00 66.50  ? 101 LEU D N   1 
ATOM   11622 C CA  . LEU D 1 93  ? -22.177 96.667  28.533 1.00 88.05  ? 101 LEU D CA  1 
ATOM   11623 C C   . LEU D 1 93  ? -21.676 97.665  27.487 1.00 105.71 ? 101 LEU D C   1 
ATOM   11624 O O   . LEU D 1 93  ? -22.234 97.717  26.387 1.00 94.88  ? 101 LEU D O   1 
ATOM   11625 C CB  . LEU D 1 93  ? -23.213 97.318  29.456 1.00 73.90  ? 101 LEU D CB  1 
ATOM   11626 C CG  . LEU D 1 93  ? -23.761 96.466  30.589 1.00 65.27  ? 101 LEU D CG  1 
ATOM   11627 C CD1 . LEU D 1 93  ? -24.348 97.453  31.541 1.00 66.50  ? 101 LEU D CD1 1 
ATOM   11628 C CD2 . LEU D 1 93  ? -24.780 95.484  30.027 1.00 76.00  ? 101 LEU D CD2 1 
ATOM   11629 N N   . GLN D 1 94  ? -20.610 98.427  27.814 1.00 87.69  ? 102 GLN D N   1 
ATOM   11630 C CA  . GLN D 1 94  ? -19.993 99.325  26.844 1.00 86.05  ? 102 GLN D CA  1 
ATOM   11631 C C   . GLN D 1 94  ? -19.445 98.514  25.670 1.00 96.57  ? 102 GLN D C   1 
ATOM   11632 O O   . GLN D 1 94  ? -19.832 98.720  24.521 1.00 78.30  ? 102 GLN D O   1 
ATOM   11633 C CB  . GLN D 1 94  ? -18.888 100.212 27.420 1.00 57.86  ? 102 GLN D CB  1 
ATOM   11634 C CG  . GLN D 1 94  ? -19.474 101.290 28.328 1.00 87.70  ? 102 GLN D CG  1 
ATOM   11635 C CD  . GLN D 1 94  ? -18.468 101.944 29.249 1.00 104.99 ? 102 GLN D CD  1 
ATOM   11636 O OE1 . GLN D 1 94  ? -18.793 102.376 30.381 1.00 78.92  ? 102 GLN D OE1 1 
ATOM   11637 N NE2 . GLN D 1 94  ? -17.223 101.929 28.777 1.00 92.27  ? 102 GLN D NE2 1 
ATOM   11638 N N   . ALA D 1 95  ? -18.571 97.556  25.980 1.00 98.84  ? 103 ALA D N   1 
ATOM   11639 C CA  . ALA D 1 95  ? -17.884 96.749  24.986 1.00 79.19  ? 103 ALA D CA  1 
ATOM   11640 C C   . ALA D 1 95  ? -18.867 96.222  23.938 1.00 106.01 ? 103 ALA D C   1 
ATOM   11641 O O   . ALA D 1 95  ? -18.505 96.068  22.765 1.00 109.85 ? 103 ALA D O   1 
ATOM   11642 C CB  . ALA D 1 95  ? -17.188 95.619  25.705 1.00 71.25  ? 103 ALA D CB  1 
ATOM   11643 N N   . TYR D 1 96  ? -20.109 95.940  24.370 1.00 97.76  ? 104 TYR D N   1 
ATOM   11644 C CA  . TYR D 1 96  ? -21.098 95.388  23.460 1.00 87.11  ? 104 TYR D CA  1 
ATOM   11645 C C   . TYR D 1 96  ? -22.112 96.439  23.029 1.00 82.04  ? 104 TYR D C   1 
ATOM   11646 O O   . TYR D 1 96  ? -23.099 96.050  22.411 1.00 95.91  ? 104 TYR D O   1 
ATOM   11647 C CB  . TYR D 1 96  ? -21.763 94.086  23.907 1.00 73.75  ? 104 TYR D CB  1 
ATOM   11648 C CG  . TYR D 1 96  ? -20.774 92.926  23.931 1.00 72.88  ? 104 TYR D CG  1 
ATOM   11649 C CD1 . TYR D 1 96  ? -20.553 92.121  22.805 1.00 67.98  ? 104 TYR D CD1 1 
ATOM   11650 C CD2 . TYR D 1 96  ? -20.051 92.641  25.074 1.00 57.60  ? 104 TYR D CD2 1 
ATOM   11651 C CE1 . TYR D 1 96  ? -19.667 91.053  22.815 1.00 68.50  ? 104 TYR D CE1 1 
ATOM   11652 C CE2 . TYR D 1 96  ? -19.159 91.581  25.097 1.00 71.22  ? 104 TYR D CE2 1 
ATOM   11653 C CZ  . TYR D 1 96  ? -18.959 90.785  23.982 1.00 84.71  ? 104 TYR D CZ  1 
ATOM   11654 O OH  . TYR D 1 96  ? -18.073 89.735  24.118 1.00 87.21  ? 104 TYR D OH  1 
ATOM   11655 N N   . LYS D 1 97  ? -21.857 97.731  23.339 1.00 71.19  ? 105 LYS D N   1 
ATOM   11656 C CA  . LYS D 1 97  ? -22.677 98.865  22.912 1.00 68.07  ? 105 LYS D CA  1 
ATOM   11657 C C   . LYS D 1 97  ? -24.135 98.597  23.313 1.00 65.33  ? 105 LYS D C   1 
ATOM   11658 O O   . LYS D 1 97  ? -25.043 98.716  22.506 1.00 77.33  ? 105 LYS D O   1 
ATOM   11659 C CB  . LYS D 1 97  ? -22.469 99.192  21.408 1.00 69.30  ? 105 LYS D CB  1 
ATOM   11660 C CG  . LYS D 1 97  ? -21.250 100.052 20.953 1.00 67.09  ? 105 LYS D CG  1 
ATOM   11661 C CD  . LYS D 1 97  ? -20.477 99.892  19.628 1.00 55.85  ? 105 LYS D CD  1 
ATOM   11662 C CE  . LYS D 1 97  ? -20.934 99.855  18.126 1.00 55.38  ? 105 LYS D CE  1 
ATOM   11663 N NZ  . LYS D 1 97  ? -21.663 100.896 17.362 1.00 57.44  ? 105 LYS D NZ  1 
ATOM   11664 N N   . LEU D 1 98  ? -24.361 98.216  24.558 1.00 60.76  ? 106 LEU D N   1 
ATOM   11665 C CA  . LEU D 1 98  ? -25.714 97.926  25.011 1.00 71.38  ? 106 LEU D CA  1 
ATOM   11666 C C   . LEU D 1 98  ? -26.217 99.066  25.917 1.00 87.96  ? 106 LEU D C   1 
ATOM   11667 O O   . LEU D 1 98  ? -25.513 99.519  26.862 1.00 61.57  ? 106 LEU D O   1 
ATOM   11668 C CB  . LEU D 1 98  ? -25.686 96.643  25.841 1.00 87.64  ? 106 LEU D CB  1 
ATOM   11669 C CG  . LEU D 1 98  ? -24.963 95.435  25.264 1.00 75.26  ? 106 LEU D CG  1 
ATOM   11670 C CD1 . LEU D 1 98  ? -24.905 94.336  26.297 1.00 83.00  ? 106 LEU D CD1 1 
ATOM   11671 C CD2 . LEU D 1 98  ? -25.698 94.968  24.061 1.00 62.24  ? 106 LEU D CD2 1 
ATOM   11672 N N   . ASP D 1 99  ? -27.492 99.430  25.688 1.00 70.15  ? 107 ASP D N   1 
ATOM   11673 C CA  . ASP D 1 99  ? -28.204 100.370 26.543 1.00 71.16  ? 107 ASP D CA  1 
ATOM   11674 C C   . ASP D 1 99  ? -28.455 99.789  27.953 1.00 76.88  ? 107 ASP D C   1 
ATOM   11675 O O   . ASP D 1 99  ? -29.130 98.758  28.106 1.00 105.11 ? 107 ASP D O   1 
ATOM   11676 C CB  . ASP D 1 99  ? -29.457 100.881 25.841 1.00 72.73  ? 107 ASP D CB  1 
ATOM   11677 C CG  . ASP D 1 99  ? -30.300 101.754 26.748 1.00 85.46  ? 107 ASP D CG  1 
ATOM   11678 O OD1 . ASP D 1 99  ? -29.781 102.727 27.318 1.00 112.02 ? 107 ASP D OD1 1 
ATOM   11679 O OD2 . ASP D 1 99  ? -31.476 101.472 26.874 1.00 112.50 ? 107 ASP D OD2 1 
ATOM   11680 N N   . PRO D 1 100 ? -27.939 100.414 29.039 1.00 65.08  ? 108 PRO D N   1 
ATOM   11681 C CA  . PRO D 1 100 ? -28.157 99.925  30.402 1.00 63.18  ? 108 PRO D CA  1 
ATOM   11682 C C   . PRO D 1 100 ? -29.621 99.804  30.810 1.00 87.72  ? 108 PRO D C   1 
ATOM   11683 O O   . PRO D 1 100 ? -29.920 99.139  31.811 1.00 112.14 ? 108 PRO D O   1 
ATOM   11684 C CB  . PRO D 1 100 ? -27.422 100.929 31.309 1.00 43.41  ? 108 PRO D CB  1 
ATOM   11685 C CG  . PRO D 1 100 ? -26.424 101.537 30.391 1.00 63.36  ? 108 PRO D CG  1 
ATOM   11686 C CD  . PRO D 1 100 ? -27.057 101.584 29.021 1.00 71.15  ? 108 PRO D CD  1 
ATOM   11687 N N   . GLN D 1 101 ? -30.511 100.440 30.042 1.00 75.72  ? 109 GLN D N   1 
ATOM   11688 C CA  . GLN D 1 101 ? -31.914 100.319 30.403 1.00 96.53  ? 109 GLN D CA  1 
ATOM   11689 C C   . GLN D 1 101 ? -32.511 99.110  29.702 1.00 87.76  ? 109 GLN D C   1 
ATOM   11690 O O   . GLN D 1 101 ? -33.583 98.633  30.088 1.00 99.23  ? 109 GLN D O   1 
ATOM   11691 C CB  . GLN D 1 101 ? -32.758 101.580 30.215 1.00 97.00  ? 109 GLN D CB  1 
ATOM   11692 C CG  . GLN D 1 101 ? -32.620 102.621 31.305 1.00 82.06  ? 109 GLN D CG  1 
ATOM   11693 C CD  . GLN D 1 101 ? -32.204 103.928 30.666 1.00 97.77  ? 109 GLN D CD  1 
ATOM   11694 O OE1 . GLN D 1 101 ? -32.088 104.075 29.431 1.00 69.90  ? 109 GLN D OE1 1 
ATOM   11695 N NE2 . GLN D 1 101 ? -31.924 104.881 31.537 1.00 112.15 ? 109 GLN D NE2 1 
ATOM   11696 N N   . CYS D 1 102 ? -31.763 98.549  28.751 1.00 65.22  ? 110 CYS D N   1 
ATOM   11697 C CA  . CYS D 1 102 ? -32.330 97.388  28.082 1.00 82.08  ? 110 CYS D CA  1 
ATOM   11698 C C   . CYS D 1 102 ? -31.547 96.119  28.364 1.00 94.60  ? 110 CYS D C   1 
ATOM   11699 O O   . CYS D 1 102 ? -32.044 95.049  28.019 1.00 106.73 ? 110 CYS D O   1 
ATOM   11700 C CB  . CYS D 1 102 ? -32.240 97.422  26.574 1.00 67.02  ? 110 CYS D CB  1 
ATOM   11701 S SG  . CYS D 1 102 ? -32.864 98.936  25.834 1.00 108.24 ? 110 CYS D SG  1 
ATOM   11702 N N   . TRP D 1 103 ? -30.371 96.294  28.981 1.00 82.43  ? 111 TRP D N   1 
ATOM   11703 C CA  . TRP D 1 103 ? -29.516 95.174  29.310 1.00 89.52  ? 111 TRP D CA  1 
ATOM   11704 C C   . TRP D 1 103 ? -28.960 95.332  30.708 1.00 82.95  ? 111 TRP D C   1 
ATOM   11705 O O   . TRP D 1 103 ? -28.548 96.432  31.093 1.00 82.31  ? 111 TRP D O   1 
ATOM   11706 C CB  . TRP D 1 103 ? -28.384 95.002  28.274 1.00 82.39  ? 111 TRP D CB  1 
ATOM   11707 C CG  . TRP D 1 103 ? -28.858 94.426  26.962 1.00 76.85  ? 111 TRP D CG  1 
ATOM   11708 C CD1 . TRP D 1 103 ? -29.178 95.155  25.871 1.00 64.81  ? 111 TRP D CD1 1 
ATOM   11709 C CD2 . TRP D 1 103 ? -29.129 93.037  26.624 1.00 86.18  ? 111 TRP D CD2 1 
ATOM   11710 N NE1 . TRP D 1 103 ? -29.613 94.323  24.876 1.00 97.62  ? 111 TRP D NE1 1 
ATOM   11711 C CE2 . TRP D 1 103 ? -29.610 93.023  25.295 1.00 82.37  ? 111 TRP D CE2 1 
ATOM   11712 C CE3 . TRP D 1 103 ? -29.007 91.813  27.299 1.00 72.30  ? 111 TRP D CE3 1 
ATOM   11713 C CZ2 . TRP D 1 103 ? -29.966 91.854  24.620 1.00 76.90  ? 111 TRP D CZ2 1 
ATOM   11714 C CZ3 . TRP D 1 103 ? -29.334 90.656  26.625 1.00 93.37  ? 111 TRP D CZ3 1 
ATOM   11715 C CH2 . TRP D 1 103 ? -29.843 90.681  25.327 1.00 89.75  ? 111 TRP D CH2 1 
ATOM   11716 N N   . GLY D 1 104 ? -28.926 94.196  31.417 1.00 85.45  ? 112 GLY D N   1 
ATOM   11717 C CA  . GLY D 1 104 ? -28.052 94.069  32.572 1.00 107.48 ? 112 GLY D CA  1 
ATOM   11718 C C   . GLY D 1 104 ? -27.023 92.961  32.341 1.00 95.13  ? 112 GLY D C   1 
ATOM   11719 O O   . GLY D 1 104 ? -27.129 92.176  31.401 1.00 87.14  ? 112 GLY D O   1 
ATOM   11720 N N   . VAL D 1 105 ? -26.038 92.874  33.228 1.00 77.99  ? 113 VAL D N   1 
ATOM   11721 C CA  . VAL D 1 105 ? -25.048 91.822  33.084 1.00 90.50  ? 113 VAL D CA  1 
ATOM   11722 C C   . VAL D 1 105 ? -24.588 91.370  34.470 1.00 96.42  ? 113 VAL D C   1 
ATOM   11723 O O   . VAL D 1 105 ? -24.347 92.182  35.343 1.00 123.99 ? 113 VAL D O   1 
ATOM   11724 C CB  . VAL D 1 105 ? -23.841 92.307  32.258 1.00 88.50  ? 113 VAL D CB  1 
ATOM   11725 C CG1 . VAL D 1 105 ? -23.119 93.451  32.958 1.00 80.69  ? 113 VAL D CG1 1 
ATOM   11726 C CG2 . VAL D 1 105 ? -22.803 91.212  32.062 1.00 92.26  ? 113 VAL D CG2 1 
ATOM   11727 N N   . ASN D 1 106 ? -24.441 90.064  34.661 1.00 90.40  ? 114 ASN D N   1 
ATOM   11728 C CA  . ASN D 1 106 ? -23.809 89.559  35.855 1.00 72.99  ? 114 ASN D CA  1 
ATOM   11729 C C   . ASN D 1 106 ? -22.419 89.059  35.466 1.00 80.55  ? 114 ASN D C   1 
ATOM   11730 O O   . ASN D 1 106 ? -22.256 88.316  34.493 1.00 69.39  ? 114 ASN D O   1 
ATOM   11731 C CB  . ASN D 1 106 ? -24.710 88.456  36.352 1.00 72.19  ? 114 ASN D CB  1 
ATOM   11732 C CG  . ASN D 1 106 ? -24.231 87.722  37.580 1.00 73.84  ? 114 ASN D CG  1 
ATOM   11733 O OD1 . ASN D 1 106 ? -23.035 87.554  37.868 1.00 48.09  ? 114 ASN D OD1 1 
ATOM   11734 N ND2 . ASN D 1 106 ? -25.221 87.174  38.264 1.00 93.20  ? 114 ASN D ND2 1 
ATOM   11735 N N   . VAL D 1 107 ? -21.398 89.492  36.215 1.00 66.96  ? 115 VAL D N   1 
ATOM   11736 C CA  . VAL D 1 107 ? -20.015 89.187  35.870 1.00 51.36  ? 115 VAL D CA  1 
ATOM   11737 C C   . VAL D 1 107 ? -19.392 88.267  36.928 1.00 57.55  ? 115 VAL D C   1 
ATOM   11738 O O   . VAL D 1 107 ? -18.169 88.254  37.119 1.00 44.47  ? 115 VAL D O   1 
ATOM   11739 C CB  . VAL D 1 107 ? -19.232 90.522  35.802 1.00 62.26  ? 115 VAL D CB  1 
ATOM   11740 C CG1 . VAL D 1 107 ? -19.600 91.360  34.581 1.00 68.75  ? 115 VAL D CG1 1 
ATOM   11741 C CG2 . VAL D 1 107 ? -19.411 91.378  37.058 1.00 63.71  ? 115 VAL D CG2 1 
ATOM   11742 N N   . GLN D 1 108 ? -20.193 87.533  37.701 1.00 72.52  ? 116 GLN D N   1 
ATOM   11743 C CA  . GLN D 1 108 ? -19.609 86.702  38.758 1.00 68.90  ? 116 GLN D CA  1 
ATOM   11744 C C   . GLN D 1 108 ? -19.336 85.265  38.305 1.00 73.27  ? 116 GLN D C   1 
ATOM   11745 O O   . GLN D 1 108 ? -18.529 84.568  38.932 1.00 65.60  ? 116 GLN D O   1 
ATOM   11746 C CB  . GLN D 1 108 ? -20.497 86.550  39.985 1.00 54.91  ? 116 GLN D CB  1 
ATOM   11747 C CG  . GLN D 1 108 ? -20.559 87.806  40.803 1.00 65.31  ? 116 GLN D CG  1 
ATOM   11748 C CD  . GLN D 1 108 ? -21.126 87.619  42.193 1.00 97.72  ? 116 GLN D CD  1 
ATOM   11749 O OE1 . GLN D 1 108 ? -21.088 86.558  42.875 1.00 80.73  ? 116 GLN D OE1 1 
ATOM   11750 N NE2 . GLN D 1 108 ? -21.655 88.773  42.567 1.00 101.61 ? 116 GLN D NE2 1 
ATOM   11751 N N   . PRO D 1 109 ? -19.999 84.736  37.247 1.00 70.14  ? 117 PRO D N   1 
ATOM   11752 C CA  . PRO D 1 109 ? -19.794 83.340  36.862 1.00 75.71  ? 117 PRO D CA  1 
ATOM   11753 C C   . PRO D 1 109 ? -18.323 82.966  36.921 1.00 67.83  ? 117 PRO D C   1 
ATOM   11754 O O   . PRO D 1 109 ? -17.478 83.682  36.386 1.00 64.66  ? 117 PRO D O   1 
ATOM   11755 C CB  . PRO D 1 109 ? -20.352 83.310  35.442 1.00 74.12  ? 117 PRO D CB  1 
ATOM   11756 C CG  . PRO D 1 109 ? -21.499 84.289  35.503 1.00 90.31  ? 117 PRO D CG  1 
ATOM   11757 C CD  . PRO D 1 109 ? -20.995 85.408  36.405 1.00 80.40  ? 117 PRO D CD  1 
ATOM   11758 N N   . TYR D 1 110 ? -18.034 81.832  37.572 1.00 68.32  ? 118 TYR D N   1 
ATOM   11759 C CA  . TYR D 1 110 ? -16.666 81.372  37.743 1.00 80.32  ? 118 TYR D CA  1 
ATOM   11760 C C   . TYR D 1 110 ? -15.994 81.011  36.417 1.00 94.78  ? 118 TYR D C   1 
ATOM   11761 O O   . TYR D 1 110 ? -14.781 81.128  36.274 1.00 76.89  ? 118 TYR D O   1 
ATOM   11762 C CB  . TYR D 1 110 ? -16.798 80.124  38.602 1.00 58.74  ? 118 TYR D CB  1 
ATOM   11763 C CG  . TYR D 1 110 ? -17.094 80.466  40.045 1.00 62.37  ? 118 TYR D CG  1 
ATOM   11764 C CD1 . TYR D 1 110 ? -16.720 81.678  40.635 1.00 54.59  ? 118 TYR D CD1 1 
ATOM   11765 C CD2 . TYR D 1 110 ? -17.648 79.486  40.849 1.00 73.08  ? 118 TYR D CD2 1 
ATOM   11766 C CE1 . TYR D 1 110 ? -16.989 81.896  41.977 1.00 73.77  ? 118 TYR D CE1 1 
ATOM   11767 C CE2 . TYR D 1 110 ? -17.868 79.683  42.205 1.00 77.37  ? 118 TYR D CE2 1 
ATOM   11768 C CZ  . TYR D 1 110 ? -17.560 80.902  42.760 1.00 83.56  ? 118 TYR D CZ  1 
ATOM   11769 O OH  . TYR D 1 110 ? -17.845 81.049  44.088 1.00 109.17 ? 118 TYR D OH  1 
ATOM   11770 N N   . SER D 1 111 ? -16.788 80.509  35.472 1.00 93.13  ? 119 SER D N   1 
ATOM   11771 C CA  . SER D 1 111 ? -16.293 80.174  34.154 1.00 84.81  ? 119 SER D CA  1 
ATOM   11772 C C   . SER D 1 111 ? -17.511 80.113  33.238 1.00 105.47 ? 119 SER D C   1 
ATOM   11773 O O   . SER D 1 111 ? -18.626 80.452  33.656 1.00 97.44  ? 119 SER D O   1 
ATOM   11774 C CB  . SER D 1 111 ? -15.525 78.867  34.201 1.00 73.80  ? 119 SER D CB  1 
ATOM   11775 O OG  . SER D 1 111 ? -14.698 78.725  33.049 1.00 89.81  ? 119 SER D OG  1 
ATOM   11776 N N   . GLY D 1 112 ? -17.311 79.620  32.010 1.00 116.61 ? 120 GLY D N   1 
ATOM   11777 C CA  . GLY D 1 112 ? -18.406 79.532  31.057 1.00 112.60 ? 120 GLY D CA  1 
ATOM   11778 C C   . GLY D 1 112 ? -19.516 78.591  31.540 1.00 88.75  ? 120 GLY D C   1 
ATOM   11779 O O   . GLY D 1 112 ? -20.672 79.002  31.746 1.00 42.45  ? 120 GLY D O   1 
ATOM   11780 N N   . SER D 1 113 ? -19.137 77.329  31.737 1.00 94.98  ? 121 SER D N   1 
ATOM   11781 C CA  . SER D 1 113 ? -20.107 76.298  32.058 1.00 96.22  ? 121 SER D CA  1 
ATOM   11782 C C   . SER D 1 113 ? -20.942 76.729  33.276 1.00 107.50 ? 121 SER D C   1 
ATOM   11783 O O   . SER D 1 113 ? -22.163 76.590  33.257 1.00 102.79 ? 121 SER D O   1 
ATOM   11784 C CB  . SER D 1 113 ? -19.456 74.932  32.268 1.00 70.01  ? 121 SER D CB  1 
ATOM   11785 O OG  . SER D 1 113 ? -18.200 74.758  31.628 1.00 55.17  ? 121 SER D OG  1 
ATOM   11786 N N   . PRO D 1 114 ? -20.352 77.224  34.404 1.00 81.05  ? 122 PRO D N   1 
ATOM   11787 C CA  . PRO D 1 114 ? -21.148 77.869  35.450 1.00 75.86  ? 122 PRO D CA  1 
ATOM   11788 C C   . PRO D 1 114 ? -22.141 78.912  34.945 1.00 73.18  ? 122 PRO D C   1 
ATOM   11789 O O   . PRO D 1 114 ? -23.277 78.963  35.415 1.00 55.66  ? 122 PRO D O   1 
ATOM   11790 C CB  . PRO D 1 114 ? -20.102 78.519  36.296 1.00 79.34  ? 122 PRO D CB  1 
ATOM   11791 C CG  . PRO D 1 114 ? -18.957 77.556  36.141 1.00 91.76  ? 122 PRO D CG  1 
ATOM   11792 C CD  . PRO D 1 114 ? -18.919 77.180  34.707 1.00 78.35  ? 122 PRO D CD  1 
ATOM   11793 N N   . ALA D 1 115 ? -21.741 79.718  33.957 1.00 69.30  ? 123 ALA D N   1 
ATOM   11794 C CA  . ALA D 1 115 ? -22.645 80.782  33.534 1.00 81.73  ? 123 ALA D CA  1 
ATOM   11795 C C   . ALA D 1 115 ? -23.912 80.180  32.913 1.00 80.44  ? 123 ALA D C   1 
ATOM   11796 O O   . ALA D 1 115 ? -25.043 80.583  33.238 1.00 77.89  ? 123 ALA D O   1 
ATOM   11797 C CB  . ALA D 1 115 ? -21.933 81.783  32.636 1.00 51.61  ? 123 ALA D CB  1 
ATOM   11798 N N   . ASN D 1 116 ? -23.719 79.173  32.056 1.00 63.91  ? 124 ASN D N   1 
ATOM   11799 C CA  . ASN D 1 116 ? -24.847 78.626  31.320 1.00 76.26  ? 124 ASN D CA  1 
ATOM   11800 C C   . ASN D 1 116 ? -25.751 77.949  32.362 1.00 88.64  ? 124 ASN D C   1 
ATOM   11801 O O   . ASN D 1 116 ? -26.987 78.097  32.356 1.00 79.01  ? 124 ASN D O   1 
ATOM   11802 C CB  . ASN D 1 116 ? -24.422 77.636  30.240 1.00 63.51  ? 124 ASN D CB  1 
ATOM   11803 C CG  . ASN D 1 116 ? -23.532 78.163  29.141 1.00 72.36  ? 124 ASN D CG  1 
ATOM   11804 O OD1 . ASN D 1 116 ? -23.143 79.348  29.077 1.00 79.49  ? 124 ASN D OD1 1 
ATOM   11805 N ND2 . ASN D 1 116 ? -23.131 77.236  28.288 1.00 93.77  ? 124 ASN D ND2 1 
ATOM   11806 N N   . PHE D 1 117 ? -25.125 77.185  33.273 1.00 71.25  ? 125 PHE D N   1 
ATOM   11807 C CA  . PHE D 1 117 ? -25.895 76.402  34.226 1.00 76.18  ? 125 PHE D CA  1 
ATOM   11808 C C   . PHE D 1 117 ? -26.762 77.362  35.033 1.00 80.24  ? 125 PHE D C   1 
ATOM   11809 O O   . PHE D 1 117 ? -27.912 77.027  35.358 1.00 78.02  ? 125 PHE D O   1 
ATOM   11810 C CB  . PHE D 1 117 ? -24.981 75.516  35.087 1.00 65.46  ? 125 PHE D CB  1 
ATOM   11811 C CG  . PHE D 1 117 ? -25.785 74.504  35.872 1.00 59.18  ? 125 PHE D CG  1 
ATOM   11812 C CD1 . PHE D 1 117 ? -26.082 73.270  35.289 1.00 87.81  ? 125 PHE D CD1 1 
ATOM   11813 C CD2 . PHE D 1 117 ? -26.342 74.817  37.114 1.00 58.97  ? 125 PHE D CD2 1 
ATOM   11814 C CE1 . PHE D 1 117 ? -26.853 72.319  35.967 1.00 95.70  ? 125 PHE D CE1 1 
ATOM   11815 C CE2 . PHE D 1 117 ? -27.119 73.874  37.793 1.00 74.29  ? 125 PHE D CE2 1 
ATOM   11816 C CZ  . PHE D 1 117 ? -27.368 72.628  37.221 1.00 86.51  ? 125 PHE D CZ  1 
ATOM   11817 N N   . ALA D 1 118 ? -26.180 78.547  35.324 1.00 62.40  ? 126 ALA D N   1 
ATOM   11818 C CA  . ALA D 1 118 ? -26.882 79.563  36.095 1.00 87.12  ? 126 ALA D CA  1 
ATOM   11819 C C   . ALA D 1 118 ? -28.136 80.037  35.349 1.00 97.41  ? 126 ALA D C   1 
ATOM   11820 O O   . ALA D 1 118 ? -29.236 80.167  35.928 1.00 72.70  ? 126 ALA D O   1 
ATOM   11821 C CB  . ALA D 1 118 ? -25.955 80.714  36.376 1.00 59.52  ? 126 ALA D CB  1 
ATOM   11822 N N   . VAL D 1 119 ? -27.964 80.284  34.043 1.00 72.54  ? 127 VAL D N   1 
ATOM   11823 C CA  . VAL D 1 119 ? -29.101 80.748  33.275 1.00 67.39  ? 127 VAL D CA  1 
ATOM   11824 C C   . VAL D 1 119 ? -30.200 79.681  33.250 1.00 77.18  ? 127 VAL D C   1 
ATOM   11825 O O   . VAL D 1 119 ? -31.385 80.061  33.327 1.00 79.86  ? 127 VAL D O   1 
ATOM   11826 C CB  . VAL D 1 119 ? -28.715 81.224  31.863 1.00 57.92  ? 127 VAL D CB  1 
ATOM   11827 C CG1 . VAL D 1 119 ? -29.938 81.543  30.984 1.00 50.08  ? 127 VAL D CG1 1 
ATOM   11828 C CG2 . VAL D 1 119 ? -27.777 82.405  31.947 1.00 56.21  ? 127 VAL D CG2 1 
ATOM   11829 N N   . TYR D 1 120 ? -29.816 78.389  33.102 1.00 61.48  ? 128 TYR D N   1 
ATOM   11830 C CA  . TYR D 1 120 ? -30.823 77.344  33.016 1.00 64.42  ? 128 TYR D CA  1 
ATOM   11831 C C   . TYR D 1 120 ? -31.546 77.225  34.354 1.00 83.68  ? 128 TYR D C   1 
ATOM   11832 O O   . TYR D 1 120 ? -32.774 77.074  34.407 1.00 81.40  ? 128 TYR D O   1 
ATOM   11833 C CB  . TYR D 1 120 ? -30.190 76.017  32.670 1.00 57.37  ? 128 TYR D CB  1 
ATOM   11834 C CG  . TYR D 1 120 ? -29.232 75.999  31.489 1.00 67.16  ? 128 TYR D CG  1 
ATOM   11835 C CD1 . TYR D 1 120 ? -29.559 76.609  30.294 1.00 75.30  ? 128 TYR D CD1 1 
ATOM   11836 C CD2 . TYR D 1 120 ? -28.027 75.292  31.545 1.00 72.30  ? 128 TYR D CD2 1 
ATOM   11837 C CE1 . TYR D 1 120 ? -28.722 76.546  29.191 1.00 62.37  ? 128 TYR D CE1 1 
ATOM   11838 C CE2 . TYR D 1 120 ? -27.181 75.206  30.456 1.00 61.16  ? 128 TYR D CE2 1 
ATOM   11839 C CZ  . TYR D 1 120 ? -27.525 75.856  29.289 1.00 70.67  ? 128 TYR D CZ  1 
ATOM   11840 O OH  . TYR D 1 120 ? -26.657 75.830  28.234 1.00 98.84  ? 128 TYR D OH  1 
ATOM   11841 N N   . THR D 1 121 ? -30.779 77.377  35.441 1.00 79.55  ? 129 THR D N   1 
ATOM   11842 C CA  . THR D 1 121 ? -31.356 77.371  36.780 1.00 88.94  ? 129 THR D CA  1 
ATOM   11843 C C   . THR D 1 121 ? -32.364 78.504  36.947 1.00 75.10  ? 129 THR D C   1 
ATOM   11844 O O   . THR D 1 121 ? -33.416 78.253  37.505 1.00 74.30  ? 129 THR D O   1 
ATOM   11845 C CB  . THR D 1 121 ? -30.308 77.407  37.888 1.00 82.82  ? 129 THR D CB  1 
ATOM   11846 O OG1 . THR D 1 121 ? -29.484 76.246  37.741 1.00 85.40  ? 129 THR D OG1 1 
ATOM   11847 C CG2 . THR D 1 121 ? -30.966 77.527  39.253 1.00 41.65  ? 129 THR D CG2 1 
ATOM   11848 N N   . ALA D 1 122 ? -32.033 79.709  36.457 1.00 64.06  ? 130 ALA D N   1 
ATOM   11849 C CA  . ALA D 1 122 ? -32.895 80.884  36.629 1.00 71.05  ? 130 ALA D CA  1 
ATOM   11850 C C   . ALA D 1 122 ? -34.150 80.816  35.755 1.00 76.09  ? 130 ALA D C   1 
ATOM   11851 O O   . ALA D 1 122 ? -35.227 81.220  36.181 1.00 74.59  ? 130 ALA D O   1 
ATOM   11852 C CB  . ALA D 1 122 ? -32.185 82.188  36.354 1.00 51.58  ? 130 ALA D CB  1 
ATOM   11853 N N   . LEU D 1 123 ? -34.006 80.334  34.520 1.00 74.26  ? 131 LEU D N   1 
ATOM   11854 C CA  . LEU D 1 123 ? -35.068 80.543  33.550 1.00 74.60  ? 131 LEU D CA  1 
ATOM   11855 C C   . LEU D 1 123 ? -35.746 79.237  33.181 1.00 64.48  ? 131 LEU D C   1 
ATOM   11856 O O   . LEU D 1 123 ? -36.887 79.289  32.741 1.00 77.02  ? 131 LEU D O   1 
ATOM   11857 C CB  . LEU D 1 123 ? -34.597 81.293  32.305 1.00 68.20  ? 131 LEU D CB  1 
ATOM   11858 C CG  . LEU D 1 123 ? -33.831 82.581  32.607 1.00 82.48  ? 131 LEU D CG  1 
ATOM   11859 C CD1 . LEU D 1 123 ? -33.415 83.268  31.312 1.00 80.57  ? 131 LEU D CD1 1 
ATOM   11860 C CD2 . LEU D 1 123 ? -34.793 83.450  33.418 1.00 77.16  ? 131 LEU D CD2 1 
ATOM   11861 N N   . VAL D 1 124 ? -35.069 78.096  33.339 1.00 53.81  ? 132 VAL D N   1 
ATOM   11862 C CA  . VAL D 1 124 ? -35.639 76.863  32.814 1.00 50.74  ? 132 VAL D CA  1 
ATOM   11863 C C   . VAL D 1 124 ? -36.291 76.072  33.932 1.00 67.71  ? 132 VAL D C   1 
ATOM   11864 O O   . VAL D 1 124 ? -37.394 75.551  33.709 1.00 81.12  ? 132 VAL D O   1 
ATOM   11865 C CB  . VAL D 1 124 ? -34.621 76.003  32.063 1.00 53.35  ? 132 VAL D CB  1 
ATOM   11866 C CG1 . VAL D 1 124 ? -35.244 74.720  31.529 1.00 48.20  ? 132 VAL D CG1 1 
ATOM   11867 C CG2 . VAL D 1 124 ? -34.021 76.833  30.932 1.00 69.88  ? 132 VAL D CG2 1 
ATOM   11868 N N   . GLU D 1 125 ? -35.614 76.074  35.109 1.00 66.51  ? 133 GLU D N   1 
ATOM   11869 C CA  . GLU D 1 125 ? -36.023 75.350  36.306 1.00 70.59  ? 133 GLU D CA  1 
ATOM   11870 C C   . GLU D 1 125 ? -35.968 73.842  36.057 1.00 87.80  ? 133 GLU D C   1 
ATOM   11871 O O   . GLU D 1 125 ? -35.886 73.383  34.910 1.00 89.67  ? 133 GLU D O   1 
ATOM   11872 C CB  . GLU D 1 125 ? -37.379 75.805  36.839 1.00 81.92  ? 133 GLU D CB  1 
ATOM   11873 C CG  . GLU D 1 125 ? -37.432 77.315  37.053 1.00 93.04  ? 133 GLU D CG  1 
ATOM   11874 C CD  . GLU D 1 125 ? -38.604 77.793  37.884 1.00 99.78  ? 133 GLU D CD  1 
ATOM   11875 O OE1 . GLU D 1 125 ? -39.733 77.282  37.691 1.00 104.46 ? 133 GLU D OE1 1 
ATOM   11876 O OE2 . GLU D 1 125 ? -38.393 78.697  38.718 1.00 113.86 ? 133 GLU D OE2 1 
ATOM   11877 N N   . PRO D 1 126 ? -35.890 73.021  37.131 1.00 74.85  ? 134 PRO D N   1 
ATOM   11878 C CA  . PRO D 1 126 ? -35.552 71.595  37.022 1.00 71.02  ? 134 PRO D CA  1 
ATOM   11879 C C   . PRO D 1 126 ? -36.431 70.835  36.041 1.00 69.42  ? 134 PRO D C   1 
ATOM   11880 O O   . PRO D 1 126 ? -37.625 70.995  36.027 1.00 55.13  ? 134 PRO D O   1 
ATOM   11881 C CB  . PRO D 1 126 ? -35.851 71.187  38.446 1.00 52.15  ? 134 PRO D CB  1 
ATOM   11882 C CG  . PRO D 1 126 ? -35.288 72.349  39.196 1.00 52.75  ? 134 PRO D CG  1 
ATOM   11883 C CD  . PRO D 1 126 ? -36.076 73.438  38.524 1.00 64.99  ? 134 PRO D CD  1 
ATOM   11884 N N   . HIS D 1 127 ? -35.805 70.080  35.159 1.00 86.69  ? 135 HIS D N   1 
ATOM   11885 C CA  . HIS D 1 127 ? -36.494 69.215  34.213 1.00 88.48  ? 135 HIS D CA  1 
ATOM   11886 C C   . HIS D 1 127 ? -37.083 70.018  33.048 1.00 91.59  ? 135 HIS D C   1 
ATOM   11887 O O   . HIS D 1 127 ? -37.748 69.453  32.158 1.00 94.64  ? 135 HIS D O   1 
ATOM   11888 C CB  . HIS D 1 127 ? -37.313 68.190  35.007 1.00 98.66  ? 135 HIS D CB  1 
ATOM   11889 C CG  . HIS D 1 127 ? -36.414 67.345  35.844 1.00 119.21 ? 135 HIS D CG  1 
ATOM   11890 N ND1 . HIS D 1 127 ? -35.530 66.435  35.294 1.00 123.04 ? 135 HIS D ND1 1 
ATOM   11891 C CD2 . HIS D 1 127 ? -36.185 67.307  37.173 1.00 127.16 ? 135 HIS D CD2 1 
ATOM   11892 C CE1 . HIS D 1 127 ? -34.810 65.872  36.246 1.00 103.66 ? 135 HIS D CE1 1 
ATOM   11893 N NE2 . HIS D 1 127 ? -35.178 66.385  37.392 1.00 122.93 ? 135 HIS D NE2 1 
ATOM   11894 N N   . GLY D 1 128 ? -36.820 71.342  33.061 1.00 66.65  ? 136 GLY D N   1 
ATOM   11895 C CA  . GLY D 1 128 ? -37.290 72.218  31.994 1.00 74.41  ? 136 GLY D CA  1 
ATOM   11896 C C   . GLY D 1 128 ? -36.627 71.813  30.689 1.00 90.95  ? 136 GLY D C   1 
ATOM   11897 O O   . GLY D 1 128 ? -35.514 71.266  30.708 1.00 97.96  ? 136 GLY D O   1 
ATOM   11898 N N   . ARG D 1 129 ? -37.325 72.045  29.563 1.00 97.63  ? 137 ARG D N   1 
ATOM   11899 C CA  . ARG D 1 129 ? -36.773 71.526  28.320 1.00 87.38  ? 137 ARG D CA  1 
ATOM   11900 C C   . ARG D 1 129 ? -35.836 72.534  27.658 1.00 96.15  ? 137 ARG D C   1 
ATOM   11901 O O   . ARG D 1 129 ? -36.190 73.680  27.445 1.00 83.19  ? 137 ARG D O   1 
ATOM   11902 C CB  . ARG D 1 129 ? -37.893 71.019  27.419 1.00 77.27  ? 137 ARG D CB  1 
ATOM   11903 C CG  . ARG D 1 129 ? -38.378 69.717  28.017 1.00 80.48  ? 137 ARG D CG  1 
ATOM   11904 C CD  . ARG D 1 129 ? -39.826 69.354  27.683 1.00 82.98  ? 137 ARG D CD  1 
ATOM   11905 N NE  . ARG D 1 129 ? -40.049 68.254  26.746 1.00 78.53  ? 137 ARG D NE  1 
ATOM   11906 C CZ  . ARG D 1 129 ? -40.666 67.106  27.083 1.00 85.40  ? 137 ARG D CZ  1 
ATOM   11907 N NH1 . ARG D 1 129 ? -41.327 66.467  26.139 1.00 107.84 ? 137 ARG D NH1 1 
ATOM   11908 N NH2 . ARG D 1 129 ? -40.740 66.634  28.321 1.00 56.97  ? 137 ARG D NH2 1 
ATOM   11909 N N   . ILE D 1 130 ? -34.660 72.062  27.243 1.00 97.00  ? 138 ILE D N   1 
ATOM   11910 C CA  . ILE D 1 130 ? -33.704 72.893  26.528 1.00 74.21  ? 138 ILE D CA  1 
ATOM   11911 C C   . ILE D 1 130 ? -33.412 72.249  25.171 1.00 69.58  ? 138 ILE D C   1 
ATOM   11912 O O   . ILE D 1 130 ? -33.478 71.029  25.042 1.00 73.85  ? 138 ILE D O   1 
ATOM   11913 C CB  . ILE D 1 130 ? -32.458 73.016  27.408 1.00 59.85  ? 138 ILE D CB  1 
ATOM   11914 C CG1 . ILE D 1 130 ? -32.790 73.811  28.700 1.00 42.59  ? 138 ILE D CG1 1 
ATOM   11915 C CG2 . ILE D 1 130 ? -31.238 73.532  26.632 1.00 43.57  ? 138 ILE D CG2 1 
ATOM   11916 C CD1 . ILE D 1 130 ? -31.648 73.761  29.727 1.00 51.09  ? 138 ILE D CD1 1 
ATOM   11917 N N   . MET D 1 131 ? -33.193 73.060  24.130 1.00 59.39  ? 139 MET D N   1 
ATOM   11918 C CA  . MET D 1 131 ? -32.640 72.542  22.873 1.00 59.55  ? 139 MET D CA  1 
ATOM   11919 C C   . MET D 1 131 ? -31.392 73.336  22.546 1.00 60.94  ? 139 MET D C   1 
ATOM   11920 O O   . MET D 1 131 ? -31.412 74.583  22.554 1.00 61.87  ? 139 MET D O   1 
ATOM   11921 C CB  . MET D 1 131 ? -33.567 72.511  21.638 1.00 53.05  ? 139 MET D CB  1 
ATOM   11922 C CG  . MET D 1 131 ? -34.825 71.655  21.807 1.00 55.98  ? 139 MET D CG  1 
ATOM   11923 S SD  . MET D 1 131 ? -36.053 71.999  20.522 1.00 79.47  ? 139 MET D SD  1 
ATOM   11924 C CE  . MET D 1 131 ? -35.668 70.956  19.108 1.00 76.04  ? 139 MET D CE  1 
ATOM   11925 N N   . GLY D 1 132 ? -30.317 72.568  22.292 1.00 60.45  ? 140 GLY D N   1 
ATOM   11926 C CA  . GLY D 1 132 ? -29.088 73.085  21.717 1.00 85.86  ? 140 GLY D CA  1 
ATOM   11927 C C   . GLY D 1 132 ? -28.602 72.201  20.570 1.00 88.94  ? 140 GLY D C   1 
ATOM   11928 O O   . GLY D 1 132 ? -29.117 71.096  20.324 1.00 69.26  ? 140 GLY D O   1 
ATOM   11929 N N   . LEU D 1 133 ? -27.561 72.685  19.885 1.00 94.80  ? 141 LEU D N   1 
ATOM   11930 C CA  . LEU D 1 133 ? -27.009 71.890  18.792 1.00 89.82  ? 141 LEU D CA  1 
ATOM   11931 C C   . LEU D 1 133 ? -26.457 70.555  19.302 1.00 78.06  ? 141 LEU D C   1 
ATOM   11932 O O   . LEU D 1 133 ? -25.682 70.569  20.207 1.00 58.73  ? 141 LEU D O   1 
ATOM   11933 C CB  . LEU D 1 133 ? -25.891 72.724  18.181 1.00 75.67  ? 141 LEU D CB  1 
ATOM   11934 C CG  . LEU D 1 133 ? -25.238 72.150  16.930 1.00 66.60  ? 141 LEU D CG  1 
ATOM   11935 C CD1 . LEU D 1 133 ? -26.220 71.803  15.821 1.00 74.21  ? 141 LEU D CD1 1 
ATOM   11936 C CD2 . LEU D 1 133 ? -24.236 73.181  16.458 1.00 59.67  ? 141 LEU D CD2 1 
ATOM   11937 N N   . ASP D 1 134 ? -26.766 69.407  18.688 1.00 99.14  ? 142 ASP D N   1 
ATOM   11938 C CA  . ASP D 1 134 ? -26.216 68.116  19.099 1.00 84.46  ? 142 ASP D CA  1 
ATOM   11939 C C   . ASP D 1 134 ? -24.698 68.247  19.154 1.00 77.72  ? 142 ASP D C   1 
ATOM   11940 O O   . ASP D 1 134 ? -24.089 68.925  18.314 1.00 96.23  ? 142 ASP D O   1 
ATOM   11941 C CB  . ASP D 1 134 ? -26.481 66.998  18.090 1.00 101.43 ? 142 ASP D CB  1 
ATOM   11942 C CG  . ASP D 1 134 ? -26.445 65.577  18.652 1.00 108.30 ? 142 ASP D CG  1 
ATOM   11943 O OD1 . ASP D 1 134 ? -26.071 65.451  19.801 1.00 93.67  ? 142 ASP D OD1 1 
ATOM   11944 O OD2 . ASP D 1 134 ? -26.958 64.614  18.013 1.00 115.42 ? 142 ASP D OD2 1 
ATOM   11945 N N   . LEU D 1 135 ? -24.099 67.604  20.158 1.00 62.71  ? 143 LEU D N   1 
ATOM   11946 C CA  . LEU D 1 135 ? -22.663 67.735  20.368 1.00 68.48  ? 143 LEU D CA  1 
ATOM   11947 C C   . LEU D 1 135 ? -21.822 67.365  19.135 1.00 88.20  ? 143 LEU D C   1 
ATOM   11948 O O   . LEU D 1 135 ? -21.008 68.170  18.685 1.00 84.73  ? 143 LEU D O   1 
ATOM   11949 C CB  . LEU D 1 135 ? -22.282 66.877  21.561 1.00 43.33  ? 143 LEU D CB  1 
ATOM   11950 C CG  . LEU D 1 135 ? -20.902 67.225  22.096 1.00 45.24  ? 143 LEU D CG  1 
ATOM   11951 C CD1 . LEU D 1 135 ? -20.725 68.709  22.446 1.00 47.12  ? 143 LEU D CD1 1 
ATOM   11952 C CD2 . LEU D 1 135 ? -21.162 66.442  23.320 1.00 42.74  ? 143 LEU D CD2 1 
ATOM   11953 N N   . PRO D 1 136 ? -21.980 66.162  18.522 1.00 89.53  ? 144 PRO D N   1 
ATOM   11954 C CA  . PRO D 1 136 ? -21.219 65.780  17.330 1.00 80.28  ? 144 PRO D CA  1 
ATOM   11955 C C   . PRO D 1 136 ? -21.409 66.766  16.178 1.00 90.64  ? 144 PRO D C   1 
ATOM   11956 O O   . PRO D 1 136 ? -20.606 66.771  15.256 1.00 101.32 ? 144 PRO D O   1 
ATOM   11957 C CB  . PRO D 1 136 ? -21.797 64.397  16.943 1.00 64.01  ? 144 PRO D CB  1 
ATOM   11958 C CG  . PRO D 1 136 ? -23.212 64.494  17.475 1.00 98.44  ? 144 PRO D CG  1 
ATOM   11959 C CD  . PRO D 1 136 ? -22.975 65.130  18.854 1.00 110.15 ? 144 PRO D CD  1 
ATOM   11960 N N   . ASP D 1 137 ? -22.491 67.563  16.220 1.00 78.46  ? 145 ASP D N   1 
ATOM   11961 C CA  . ASP D 1 137 ? -22.732 68.522  15.157 1.00 77.67  ? 145 ASP D CA  1 
ATOM   11962 C C   . ASP D 1 137 ? -22.143 69.894  15.499 1.00 85.45  ? 145 ASP D C   1 
ATOM   11963 O O   . ASP D 1 137 ? -22.408 70.849  14.757 1.00 71.23  ? 145 ASP D O   1 
ATOM   11964 C CB  . ASP D 1 137 ? -24.210 68.678  14.850 1.00 83.91  ? 145 ASP D CB  1 
ATOM   11965 C CG  . ASP D 1 137 ? -24.924 67.445  14.325 1.00 114.69 ? 145 ASP D CG  1 
ATOM   11966 O OD1 . ASP D 1 137 ? -24.322 66.333  14.421 1.00 94.03  ? 145 ASP D OD1 1 
ATOM   11967 O OD2 . ASP D 1 137 ? -26.071 67.611  13.835 1.00 110.25 ? 145 ASP D OD2 1 
ATOM   11968 N N   . GLY D 1 138 ? -21.378 70.009  16.613 1.00 65.90  ? 146 GLY D N   1 
ATOM   11969 C CA  . GLY D 1 138 ? -20.670 71.247  16.946 1.00 85.96  ? 146 GLY D CA  1 
ATOM   11970 C C   . GLY D 1 138 ? -21.302 71.965  18.147 1.00 96.28  ? 146 GLY D C   1 
ATOM   11971 O O   . GLY D 1 138 ? -21.014 73.160  18.398 1.00 86.51  ? 146 GLY D O   1 
ATOM   11972 N N   . GLY D 1 139 ? -22.155 71.222  18.890 1.00 74.17  ? 147 GLY D N   1 
ATOM   11973 C CA  . GLY D 1 139 ? -22.699 71.728  20.138 1.00 76.62  ? 147 GLY D CA  1 
ATOM   11974 C C   . GLY D 1 139 ? -21.647 71.752  21.241 1.00 87.00  ? 147 GLY D C   1 
ATOM   11975 O O   . GLY D 1 139 ? -20.511 71.328  21.003 1.00 109.66 ? 147 GLY D O   1 
ATOM   11976 N N   . HIS D 1 140 ? -22.006 72.282  22.429 1.00 74.63  ? 148 HIS D N   1 
ATOM   11977 C CA  . HIS D 1 140 ? -21.118 72.163  23.587 1.00 92.80  ? 148 HIS D CA  1 
ATOM   11978 C C   . HIS D 1 140 ? -21.814 71.363  24.676 1.00 89.10  ? 148 HIS D C   1 
ATOM   11979 O O   . HIS D 1 140 ? -23.044 71.460  24.767 1.00 85.14  ? 148 HIS D O   1 
ATOM   11980 C CB  . HIS D 1 140 ? -20.694 73.518  24.160 1.00 100.72 ? 148 HIS D CB  1 
ATOM   11981 C CG  . HIS D 1 140 ? -19.678 73.357  25.246 1.00 107.65 ? 148 HIS D CG  1 
ATOM   11982 N ND1 . HIS D 1 140 ? -19.688 74.087  26.415 1.00 92.28  ? 148 HIS D ND1 1 
ATOM   11983 C CD2 . HIS D 1 140 ? -18.668 72.476  25.368 1.00 139.77 ? 148 HIS D CD2 1 
ATOM   11984 C CE1 . HIS D 1 140 ? -18.653 73.733  27.175 1.00 108.90 ? 148 HIS D CE1 1 
ATOM   11985 N NE2 . HIS D 1 140 ? -18.035 72.734  26.572 1.00 150.57 ? 148 HIS D NE2 1 
ATOM   11986 N N   . LEU D 1 141 ? -21.040 70.614  25.499 1.00 81.72  ? 149 LEU D N   1 
ATOM   11987 C CA  . LEU D 1 141 ? -21.657 69.815  26.564 1.00 76.98  ? 149 LEU D CA  1 
ATOM   11988 C C   . LEU D 1 141 ? -22.713 70.584  27.348 1.00 72.23  ? 149 LEU D C   1 
ATOM   11989 O O   . LEU D 1 141 ? -23.826 70.074  27.500 1.00 49.01  ? 149 LEU D O   1 
ATOM   11990 C CB  . LEU D 1 141 ? -20.768 69.054  27.537 1.00 51.31  ? 149 LEU D CB  1 
ATOM   11991 C CG  . LEU D 1 141 ? -20.917 67.527  27.478 1.00 35.32  ? 149 LEU D CG  1 
ATOM   11992 C CD1 . LEU D 1 141 ? -20.991 66.985  26.031 1.00 24.48  ? 149 LEU D CD1 1 
ATOM   11993 C CD2 . LEU D 1 141 ? -19.640 67.189  28.284 1.00 28.94  ? 149 LEU D CD2 1 
ATOM   11994 N N   . THR D 1 142 ? -22.346 71.787  27.812 1.00 76.94  ? 150 THR D N   1 
ATOM   11995 C CA  . THR D 1 142 ? -23.270 72.603  28.601 1.00 88.31  ? 150 THR D CA  1 
ATOM   11996 C C   . THR D 1 142 ? -24.580 72.961  27.867 1.00 78.62  ? 150 THR D C   1 
ATOM   11997 O O   . THR D 1 142 ? -25.480 73.515  28.506 1.00 54.90  ? 150 THR D O   1 
ATOM   11998 C CB  . THR D 1 142 ? -22.564 73.876  29.062 1.00 78.44  ? 150 THR D CB  1 
ATOM   11999 O OG1 . THR D 1 142 ? -22.153 74.399  27.804 1.00 72.91  ? 150 THR D OG1 1 
ATOM   12000 C CG2 . THR D 1 142 ? -21.420 73.558  30.000 1.00 71.41  ? 150 THR D CG2 1 
ATOM   12001 N N   . HIS D 1 143 ? -24.692 72.652  26.559 1.00 53.33  ? 151 HIS D N   1 
ATOM   12002 C CA  . HIS D 1 143 ? -25.889 72.935  25.807 1.00 56.40  ? 151 HIS D CA  1 
ATOM   12003 C C   . HIS D 1 143 ? -26.770 71.696  25.800 1.00 72.59  ? 151 HIS D C   1 
ATOM   12004 O O   . HIS D 1 143 ? -27.784 71.674  25.108 1.00 114.83 ? 151 HIS D O   1 
ATOM   12005 C CB  . HIS D 1 143 ? -25.532 73.308  24.365 1.00 75.10  ? 151 HIS D CB  1 
ATOM   12006 C CG  . HIS D 1 143 ? -24.682 74.508  24.218 1.00 79.67  ? 151 HIS D CG  1 
ATOM   12007 N ND1 . HIS D 1 143 ? -24.301 74.976  22.981 1.00 80.87  ? 151 HIS D ND1 1 
ATOM   12008 C CD2 . HIS D 1 143 ? -24.227 75.387  25.151 1.00 75.08  ? 151 HIS D CD2 1 
ATOM   12009 C CE1 . HIS D 1 143 ? -23.599 76.111  23.182 1.00 91.57  ? 151 HIS D CE1 1 
ATOM   12010 N NE2 . HIS D 1 143 ? -23.500 76.347  24.500 1.00 67.22  ? 151 HIS D NE2 1 
ATOM   12011 N N   . GLY D 1 144 ? -26.395 70.707  26.601 1.00 70.37  ? 152 GLY D N   1 
ATOM   12012 C CA  . GLY D 1 144 ? -27.160 69.479  26.690 1.00 80.66  ? 152 GLY D CA  1 
ATOM   12013 C C   . GLY D 1 144 ? -26.405 68.331  26.026 1.00 103.93 ? 152 GLY D C   1 
ATOM   12014 O O   . GLY D 1 144 ? -25.784 68.512  24.978 1.00 106.54 ? 152 GLY D O   1 
ATOM   12015 N N   . PHE D 1 145 ? -26.461 67.138  26.632 1.00 89.44  ? 153 PHE D N   1 
ATOM   12016 C CA  . PHE D 1 145 ? -26.075 65.936  25.909 1.00 78.84  ? 153 PHE D CA  1 
ATOM   12017 C C   . PHE D 1 145 ? -26.425 64.722  26.757 1.00 112.79 ? 153 PHE D C   1 
ATOM   12018 O O   . PHE D 1 145 ? -26.061 64.598  27.952 1.00 93.28  ? 153 PHE D O   1 
ATOM   12019 C CB  . PHE D 1 145 ? -24.566 65.998  25.753 1.00 79.46  ? 153 PHE D CB  1 
ATOM   12020 C CG  . PHE D 1 145 ? -23.903 64.814  25.096 1.00 67.30  ? 153 PHE D CG  1 
ATOM   12021 C CD1 . PHE D 1 145 ? -24.262 64.412  23.820 1.00 46.56  ? 153 PHE D CD1 1 
ATOM   12022 C CD2 . PHE D 1 145 ? -22.824 64.190  25.722 1.00 71.45  ? 153 PHE D CD2 1 
ATOM   12023 C CE1 . PHE D 1 145 ? -23.560 63.372  23.181 1.00 48.80  ? 153 PHE D CE1 1 
ATOM   12024 C CE2 . PHE D 1 145 ? -22.138 63.143  25.097 1.00 64.95  ? 153 PHE D CE2 1 
ATOM   12025 C CZ  . PHE D 1 145 ? -22.484 62.756  23.803 1.00 50.93  ? 153 PHE D CZ  1 
ATOM   12026 N N   . MET D 1 146 ? -27.130 63.810  26.083 1.00 99.19  ? 154 MET D N   1 
ATOM   12027 C CA  . MET D 1 146 ? -27.376 62.503  26.661 1.00 85.34  ? 154 MET D CA  1 
ATOM   12028 C C   . MET D 1 146 ? -27.366 61.472  25.537 1.00 80.93  ? 154 MET D C   1 
ATOM   12029 O O   . MET D 1 146 ? -27.727 61.771  24.406 1.00 78.15  ? 154 MET D O   1 
ATOM   12030 C CB  . MET D 1 146 ? -28.684 62.499  27.465 1.00 75.02  ? 154 MET D CB  1 
ATOM   12031 C CG  . MET D 1 146 ? -29.935 62.721  26.552 1.00 62.64  ? 154 MET D CG  1 
ATOM   12032 S SD  . MET D 1 146 ? -31.631 62.983  27.166 1.00 67.63  ? 154 MET D SD  1 
ATOM   12033 C CE  . MET D 1 146 ? -31.930 61.653  28.348 1.00 54.29  ? 154 MET D CE  1 
ATOM   12034 N N   . THR D 1 147 ? -26.912 60.260  25.879 1.00 84.51  ? 155 THR D N   1 
ATOM   12035 C CA  . THR D 1 147 ? -26.973 59.105  24.994 1.00 75.63  ? 155 THR D CA  1 
ATOM   12036 C C   . THR D 1 147 ? -28.119 58.209  25.454 1.00 73.19  ? 155 THR D C   1 
ATOM   12037 O O   . THR D 1 147 ? -28.554 58.397  26.592 1.00 73.84  ? 155 THR D O   1 
ATOM   12038 C CB  . THR D 1 147 ? -25.658 58.376  25.212 1.00 70.46  ? 155 THR D CB  1 
ATOM   12039 O OG1 . THR D 1 147 ? -25.642 57.782  26.513 1.00 65.13  ? 155 THR D OG1 1 
ATOM   12040 C CG2 . THR D 1 147 ? -24.462 59.250  24.928 1.00 61.33  ? 155 THR D CG2 1 
ATOM   12041 N N   . ASP D 1 148 ? -28.495 57.179  24.679 1.00 62.02  ? 156 ASP D N   1 
ATOM   12042 C CA  . ASP D 1 148 ? -29.520 56.253  25.145 1.00 67.85  ? 156 ASP D CA  1 
ATOM   12043 C C   . ASP D 1 148 ? -29.093 55.635  26.507 1.00 69.69  ? 156 ASP D C   1 
ATOM   12044 O O   . ASP D 1 148 ? -29.962 55.299  27.355 1.00 67.26  ? 156 ASP D O   1 
ATOM   12045 C CB  . ASP D 1 148 ? -29.892 55.272  24.041 1.00 70.94  ? 156 ASP D CB  1 
ATOM   12046 C CG  . ASP D 1 148 ? -28.835 54.187  23.846 1.00 100.00 ? 156 ASP D CG  1 
ATOM   12047 O OD1 . ASP D 1 148 ? -27.628 54.439  24.173 1.00 86.59  ? 156 ASP D OD1 1 
ATOM   12048 O OD2 . ASP D 1 148 ? -29.229 53.053  23.506 1.00 127.07 ? 156 ASP D OD2 1 
ATOM   12049 N N   . LYS D 1 149 ? -27.758 55.614  26.775 1.00 48.28  ? 157 LYS D N   1 
ATOM   12050 C CA  . LYS D 1 149 ? -27.203 54.926  27.944 1.00 57.88  ? 157 LYS D CA  1 
ATOM   12051 C C   . LYS D 1 149 ? -27.134 55.769  29.213 1.00 67.55  ? 157 LYS D C   1 
ATOM   12052 O O   . LYS D 1 149 ? -27.346 55.217  30.295 1.00 64.05  ? 157 LYS D O   1 
ATOM   12053 C CB  . LYS D 1 149 ? -26.071 53.890  27.787 1.00 58.13  ? 157 LYS D CB  1 
ATOM   12054 C CG  . LYS D 1 149 ? -26.537 52.516  27.183 1.00 70.25  ? 157 LYS D CG  1 
ATOM   12055 C CD  . LYS D 1 149 ? -27.551 51.606  27.889 1.00 70.98  ? 157 LYS D CD  1 
ATOM   12056 C CE  . LYS D 1 149 ? -28.648 51.030  26.979 1.00 88.16  ? 157 LYS D CE  1 
ATOM   12057 N NZ  . LYS D 1 149 ? -29.709 50.290  27.689 1.00 74.64  ? 157 LYS D NZ  1 
ATOM   12058 N N   . LYS D 1 150 ? -26.824 57.069  29.104 1.00 76.52  ? 158 LYS D N   1 
ATOM   12059 C CA  . LYS D 1 150 ? -26.672 57.868  30.327 1.00 70.42  ? 158 LYS D CA  1 
ATOM   12060 C C   . LYS D 1 150 ? -26.950 59.341  30.039 1.00 70.88  ? 158 LYS D C   1 
ATOM   12061 O O   . LYS D 1 150 ? -26.672 59.803  28.923 1.00 87.85  ? 158 LYS D O   1 
ATOM   12062 C CB  . LYS D 1 150 ? -25.297 57.827  31.020 1.00 45.27  ? 158 LYS D CB  1 
ATOM   12063 C CG  . LYS D 1 150 ? -25.485 58.201  32.485 1.00 52.94  ? 158 LYS D CG  1 
ATOM   12064 C CD  . LYS D 1 150 ? -24.403 58.444  33.551 1.00 48.31  ? 158 LYS D CD  1 
ATOM   12065 C CE  . LYS D 1 150 ? -23.501 57.357  34.210 1.00 65.34  ? 158 LYS D CE  1 
ATOM   12066 N NZ  . LYS D 1 150 ? -23.422 57.224  35.702 1.00 57.08  ? 158 LYS D NZ  1 
ATOM   12067 N N   . LYS D 1 151 ? -27.478 60.073  31.037 1.00 60.00  ? 159 LYS D N   1 
ATOM   12068 C CA  . LYS D 1 151 ? -27.488 61.523  30.939 1.00 72.66  ? 159 LYS D CA  1 
ATOM   12069 C C   . LYS D 1 151 ? -26.083 62.012  31.266 1.00 84.68  ? 159 LYS D C   1 
ATOM   12070 O O   . LYS D 1 151 ? -25.635 61.767  32.374 1.00 105.90 ? 159 LYS D O   1 
ATOM   12071 C CB  . LYS D 1 151 ? -28.476 62.113  31.950 1.00 63.52  ? 159 LYS D CB  1 
ATOM   12072 C CG  . LYS D 1 151 ? -29.880 61.905  31.405 1.00 73.16  ? 159 LYS D CG  1 
ATOM   12073 C CD  . LYS D 1 151 ? -30.987 62.642  32.147 1.00 70.90  ? 159 LYS D CD  1 
ATOM   12074 C CE  . LYS D 1 151 ? -32.247 62.049  31.606 1.00 53.92  ? 159 LYS D CE  1 
ATOM   12075 N NZ  . LYS D 1 151 ? -33.521 62.660  32.017 1.00 61.75  ? 159 LYS D NZ  1 
ATOM   12076 N N   . ILE D 1 152 ? -25.400 62.643  30.309 1.00 70.43  ? 160 ILE D N   1 
ATOM   12077 C CA  . ILE D 1 152 ? -23.962 62.841  30.435 1.00 61.10  ? 160 ILE D CA  1 
ATOM   12078 C C   . ILE D 1 152 ? -23.712 64.235  30.996 1.00 66.38  ? 160 ILE D C   1 
ATOM   12079 O O   . ILE D 1 152 ? -23.008 64.391  31.993 1.00 59.67  ? 160 ILE D O   1 
ATOM   12080 C CB  . ILE D 1 152 ? -23.252 62.777  29.073 1.00 89.64  ? 160 ILE D CB  1 
ATOM   12081 C CG1 . ILE D 1 152 ? -23.672 61.606  28.149 1.00 90.10  ? 160 ILE D CG1 1 
ATOM   12082 C CG2 . ILE D 1 152 ? -21.739 62.913  29.254 1.00 83.82  ? 160 ILE D CG2 1 
ATOM   12083 C CD1 . ILE D 1 152 ? -23.445 60.237  28.746 1.00 88.50  ? 160 ILE D CD1 1 
ATOM   12084 N N   . SER D 1 153 ? -24.182 65.268  30.269 1.00 71.75  ? 161 SER D N   1 
ATOM   12085 C CA  . SER D 1 153 ? -23.909 66.643  30.670 1.00 70.36  ? 161 SER D CA  1 
ATOM   12086 C C   . SER D 1 153 ? -24.817 66.965  31.837 1.00 70.29  ? 161 SER D C   1 
ATOM   12087 O O   . SER D 1 153 ? -25.962 66.524  31.823 1.00 80.56  ? 161 SER D O   1 
ATOM   12088 C CB  . SER D 1 153 ? -24.215 67.581  29.560 1.00 80.04  ? 161 SER D CB  1 
ATOM   12089 O OG  . SER D 1 153 ? -24.254 68.916  30.053 1.00 79.71  ? 161 SER D OG  1 
ATOM   12090 N N   . ALA D 1 154 ? -24.330 67.745  32.810 1.00 69.02  ? 162 ALA D N   1 
ATOM   12091 C CA  . ALA D 1 154 ? -25.175 68.195  33.919 1.00 55.24  ? 162 ALA D CA  1 
ATOM   12092 C C   . ALA D 1 154 ? -26.432 68.901  33.414 1.00 65.45  ? 162 ALA D C   1 
ATOM   12093 O O   . ALA D 1 154 ? -27.504 68.733  34.000 1.00 67.52  ? 162 ALA D O   1 
ATOM   12094 C CB  . ALA D 1 154 ? -24.425 69.101  34.847 1.00 42.51  ? 162 ALA D CB  1 
ATOM   12095 N N   . THR D 1 155 ? -26.312 69.631  32.291 1.00 57.61  ? 163 THR D N   1 
ATOM   12096 C CA  . THR D 1 155 ? -27.471 70.238  31.652 1.00 51.81  ? 163 THR D CA  1 
ATOM   12097 C C   . THR D 1 155 ? -28.498 69.149  31.383 1.00 60.61  ? 163 THR D C   1 
ATOM   12098 O O   . THR D 1 155 ? -29.663 69.316  31.739 1.00 87.19  ? 163 THR D O   1 
ATOM   12099 C CB  . THR D 1 155 ? -27.097 70.953  30.370 1.00 47.32  ? 163 THR D CB  1 
ATOM   12100 O OG1 . THR D 1 155 ? -26.052 71.876  30.645 1.00 63.39  ? 163 THR D OG1 1 
ATOM   12101 C CG2 . THR D 1 155 ? -28.239 71.820  29.892 1.00 48.17  ? 163 THR D CG2 1 
ATOM   12102 N N   . SER D 1 156 ? -28.040 67.995  30.880 1.00 55.01  ? 164 SER D N   1 
ATOM   12103 C CA  . SER D 1 156 ? -29.003 66.946  30.534 1.00 63.79  ? 164 SER D CA  1 
ATOM   12104 C C   . SER D 1 156 ? -29.408 66.054  31.708 1.00 66.27  ? 164 SER D C   1 
ATOM   12105 O O   . SER D 1 156 ? -30.412 65.346  31.613 1.00 84.14  ? 164 SER D O   1 
ATOM   12106 C CB  . SER D 1 156 ? -28.671 66.115  29.355 1.00 68.48  ? 164 SER D CB  1 
ATOM   12107 O OG  . SER D 1 156 ? -28.733 66.839  28.146 1.00 101.00 ? 164 SER D OG  1 
ATOM   12108 N N   . ILE D 1 157 ? -28.676 66.153  32.820 1.00 52.40  ? 165 ILE D N   1 
ATOM   12109 C CA  . ILE D 1 157 ? -29.047 65.501  34.069 1.00 64.28  ? 165 ILE D CA  1 
ATOM   12110 C C   . ILE D 1 157 ? -30.164 66.273  34.768 1.00 79.99  ? 165 ILE D C   1 
ATOM   12111 O O   . ILE D 1 157 ? -31.126 65.639  35.201 1.00 100.59 ? 165 ILE D O   1 
ATOM   12112 C CB  . ILE D 1 157 ? -27.831 65.445  35.015 1.00 62.65  ? 165 ILE D CB  1 
ATOM   12113 C CG1 . ILE D 1 157 ? -26.687 64.645  34.363 1.00 51.18  ? 165 ILE D CG1 1 
ATOM   12114 C CG2 . ILE D 1 157 ? -28.193 65.006  36.447 1.00 33.90  ? 165 ILE D CG2 1 
ATOM   12115 C CD1 . ILE D 1 157 ? -25.419 64.752  35.168 1.00 33.93  ? 165 ILE D CD1 1 
ATOM   12116 N N   . PHE D 1 158 ? -29.996 67.607  34.914 1.00 52.96  ? 166 PHE D N   1 
ATOM   12117 C CA  . PHE D 1 158 ? -30.900 68.351  35.766 1.00 74.28  ? 166 PHE D CA  1 
ATOM   12118 C C   . PHE D 1 158 ? -32.015 69.025  34.985 1.00 84.63  ? 166 PHE D C   1 
ATOM   12119 O O   . PHE D 1 158 ? -32.986 69.444  35.618 1.00 112.78 ? 166 PHE D O   1 
ATOM   12120 C CB  . PHE D 1 158 ? -30.145 69.432  36.524 1.00 83.30  ? 166 PHE D CB  1 
ATOM   12121 C CG  . PHE D 1 158 ? -29.128 68.889  37.500 1.00 79.74  ? 166 PHE D CG  1 
ATOM   12122 C CD1 . PHE D 1 158 ? -29.527 68.298  38.704 1.00 80.36  ? 166 PHE D CD1 1 
ATOM   12123 C CD2 . PHE D 1 158 ? -27.772 69.008  37.215 1.00 76.26  ? 166 PHE D CD2 1 
ATOM   12124 C CE1 . PHE D 1 158 ? -28.567 67.853  39.622 1.00 80.05  ? 166 PHE D CE1 1 
ATOM   12125 C CE2 . PHE D 1 158 ? -26.812 68.565  38.130 1.00 87.08  ? 166 PHE D CE2 1 
ATOM   12126 C CZ  . PHE D 1 158 ? -27.208 67.999  39.345 1.00 76.16  ? 166 PHE D CZ  1 
ATOM   12127 N N   . PHE D 1 159 ? -31.868 69.096  33.650 1.00 63.12  ? 167 PHE D N   1 
ATOM   12128 C CA  . PHE D 1 159 ? -32.909 69.548  32.725 1.00 69.49  ? 167 PHE D CA  1 
ATOM   12129 C C   . PHE D 1 159 ? -33.165 68.465  31.682 1.00 80.83  ? 167 PHE D C   1 
ATOM   12130 O O   . PHE D 1 159 ? -32.348 67.569  31.488 1.00 120.45 ? 167 PHE D O   1 
ATOM   12131 C CB  . PHE D 1 159 ? -32.485 70.873  32.079 1.00 68.52  ? 167 PHE D CB  1 
ATOM   12132 C CG  . PHE D 1 159 ? -32.006 71.895  33.105 1.00 77.93  ? 167 PHE D CG  1 
ATOM   12133 C CD1 . PHE D 1 159 ? -32.915 72.685  33.820 1.00 77.93  ? 167 PHE D CD1 1 
ATOM   12134 C CD2 . PHE D 1 159 ? -30.644 72.058  33.366 1.00 76.77  ? 167 PHE D CD2 1 
ATOM   12135 C CE1 . PHE D 1 159 ? -32.475 73.597  34.771 1.00 87.22  ? 167 PHE D CE1 1 
ATOM   12136 C CE2 . PHE D 1 159 ? -30.218 72.947  34.353 1.00 83.22  ? 167 PHE D CE2 1 
ATOM   12137 C CZ  . PHE D 1 159 ? -31.125 73.723  35.047 1.00 75.54  ? 167 PHE D CZ  1 
ATOM   12138 N N   . GLU D 1 160 ? -34.272 68.562  30.952 1.00 72.59  ? 168 GLU D N   1 
ATOM   12139 C CA  . GLU D 1 160 ? -34.492 67.692  29.800 1.00 74.46  ? 168 GLU D CA  1 
ATOM   12140 C C   . GLU D 1 160 ? -34.009 68.393  28.522 1.00 90.44  ? 168 GLU D C   1 
ATOM   12141 O O   . GLU D 1 160 ? -34.644 69.364  28.021 1.00 59.68  ? 168 GLU D O   1 
ATOM   12142 C CB  . GLU D 1 160 ? -35.955 67.258  29.738 1.00 42.15  ? 168 GLU D CB  1 
ATOM   12143 C CG  . GLU D 1 160 ? -36.411 66.480  30.966 1.00 63.74  ? 168 GLU D CG  1 
ATOM   12144 C CD  . GLU D 1 160 ? -35.803 65.096  31.245 1.00 105.84 ? 168 GLU D CD  1 
ATOM   12145 O OE1 . GLU D 1 160 ? -35.849 64.088  30.446 1.00 73.75  ? 168 GLU D OE1 1 
ATOM   12146 O OE2 . GLU D 1 160 ? -35.309 64.992  32.381 1.00 131.93 ? 168 GLU D OE2 1 
ATOM   12147 N N   . SER D 1 161 ? -32.882 67.890  27.977 1.00 76.04  ? 169 SER D N   1 
ATOM   12148 C CA  . SER D 1 161 ? -32.429 68.532  26.758 1.00 82.17  ? 169 SER D CA  1 
ATOM   12149 C C   . SER D 1 161 ? -32.769 67.609  25.600 1.00 80.67  ? 169 SER D C   1 
ATOM   12150 O O   . SER D 1 161 ? -32.941 66.436  25.844 1.00 79.54  ? 169 SER D O   1 
ATOM   12151 C CB  . SER D 1 161 ? -30.966 68.801  26.790 1.00 86.50  ? 169 SER D CB  1 
ATOM   12152 O OG  . SER D 1 161 ? -30.276 67.767  26.113 1.00 78.42  ? 169 SER D OG  1 
ATOM   12153 N N   . MET D 1 162 ? -32.885 68.178  24.407 1.00 82.90  ? 170 MET D N   1 
ATOM   12154 C CA  . MET D 1 162 ? -32.920 67.466  23.152 1.00 94.20  ? 170 MET D CA  1 
ATOM   12155 C C   . MET D 1 162 ? -32.101 68.286  22.172 1.00 76.12  ? 170 MET D C   1 
ATOM   12156 O O   . MET D 1 162 ? -32.264 69.501  22.134 1.00 75.23  ? 170 MET D O   1 
ATOM   12157 C CB  . MET D 1 162 ? -34.360 67.429  22.606 1.00 117.88 ? 170 MET D CB  1 
ATOM   12158 C CG  . MET D 1 162 ? -34.430 66.722  21.242 1.00 92.78  ? 170 MET D CG  1 
ATOM   12159 S SD  . MET D 1 162 ? -36.009 65.948  20.896 1.00 93.01  ? 170 MET D SD  1 
ATOM   12160 C CE  . MET D 1 162 ? -36.607 67.530  20.298 1.00 77.25  ? 170 MET D CE  1 
ATOM   12161 N N   . PRO D 1 163 ? -31.283 67.654  21.304 1.00 88.09  ? 171 PRO D N   1 
ATOM   12162 C CA  . PRO D 1 163 ? -30.558 68.384  20.243 1.00 97.05  ? 171 PRO D CA  1 
ATOM   12163 C C   . PRO D 1 163 ? -31.279 68.785  18.953 1.00 114.52 ? 171 PRO D C   1 
ATOM   12164 O O   . PRO D 1 163 ? -32.259 68.146  18.548 1.00 152.10 ? 171 PRO D O   1 
ATOM   12165 C CB  . PRO D 1 163 ? -29.409 67.440  19.922 1.00 86.37  ? 171 PRO D CB  1 
ATOM   12166 C CG  . PRO D 1 163 ? -30.039 66.054  20.160 1.00 107.90 ? 171 PRO D CG  1 
ATOM   12167 C CD  . PRO D 1 163 ? -30.997 66.210  21.338 1.00 80.23  ? 171 PRO D CD  1 
ATOM   12168 N N   . TYR D 1 164 ? -30.795 69.876  18.331 1.00 117.44 ? 172 TYR D N   1 
ATOM   12169 C CA  . TYR D 1 164 ? -31.132 70.240  16.956 1.00 104.89 ? 172 TYR D CA  1 
ATOM   12170 C C   . TYR D 1 164 ? -29.874 69.999  16.129 1.00 80.77  ? 172 TYR D C   1 
ATOM   12171 O O   . TYR D 1 164 ? -28.784 70.075  16.680 1.00 47.55  ? 172 TYR D O   1 
ATOM   12172 C CB  . TYR D 1 164 ? -31.684 71.662  16.755 1.00 96.96  ? 172 TYR D CB  1 
ATOM   12173 C CG  . TYR D 1 164 ? -30.878 72.867  17.240 1.00 69.93  ? 172 TYR D CG  1 
ATOM   12174 C CD1 . TYR D 1 164 ? -29.865 73.378  16.467 1.00 67.43  ? 172 TYR D CD1 1 
ATOM   12175 C CD2 . TYR D 1 164 ? -31.135 73.539  18.426 1.00 96.87  ? 172 TYR D CD2 1 
ATOM   12176 C CE1 . TYR D 1 164 ? -29.116 74.488  16.809 1.00 82.45  ? 172 TYR D CE1 1 
ATOM   12177 C CE2 . TYR D 1 164 ? -30.378 74.643  18.812 1.00 120.72 ? 172 TYR D CE2 1 
ATOM   12178 C CZ  . TYR D 1 164 ? -29.353 75.129  18.006 1.00 118.67 ? 172 TYR D CZ  1 
ATOM   12179 O OH  . TYR D 1 164 ? -28.501 76.191  18.267 1.00 114.44 ? 172 TYR D OH  1 
ATOM   12180 N N   . LYS D 1 165 ? -30.002 69.695  14.824 1.00 87.97  ? 173 LYS D N   1 
ATOM   12181 C CA  . LYS D 1 165 ? -28.826 69.164  14.142 1.00 75.79  ? 173 LYS D CA  1 
ATOM   12182 C C   . LYS D 1 165 ? -28.480 70.018  12.933 1.00 82.87  ? 173 LYS D C   1 
ATOM   12183 O O   . LYS D 1 165 ? -29.293 70.885  12.506 1.00 82.11  ? 173 LYS D O   1 
ATOM   12184 C CB  . LYS D 1 165 ? -28.956 67.687  13.752 1.00 67.47  ? 173 LYS D CB  1 
ATOM   12185 C CG  . LYS D 1 165 ? -29.112 66.792  14.986 1.00 71.93  ? 173 LYS D CG  1 
ATOM   12186 C CD  . LYS D 1 165 ? -29.158 65.329  14.571 1.00 83.91  ? 173 LYS D CD  1 
ATOM   12187 C CE  . LYS D 1 165 ? -27.798 64.904  14.091 1.00 87.38  ? 173 LYS D CE  1 
ATOM   12188 N NZ  . LYS D 1 165 ? -26.971 64.688  15.272 1.00 66.79  ? 173 LYS D NZ  1 
ATOM   12189 N N   . VAL D 1 166 ? -27.232 69.788  12.466 1.00 59.49  ? 174 VAL D N   1 
ATOM   12190 C CA  . VAL D 1 166 ? -26.707 70.460  11.292 1.00 72.14  ? 174 VAL D CA  1 
ATOM   12191 C C   . VAL D 1 166 ? -26.895 69.520  10.117 1.00 63.32  ? 174 VAL D C   1 
ATOM   12192 O O   . VAL D 1 166 ? -26.572 68.358  10.242 1.00 47.57  ? 174 VAL D O   1 
ATOM   12193 C CB  . VAL D 1 166 ? -25.215 70.794  11.502 1.00 95.78  ? 174 VAL D CB  1 
ATOM   12194 C CG1 . VAL D 1 166 ? -24.414 71.199  10.252 1.00 70.31  ? 174 VAL D CG1 1 
ATOM   12195 C CG2 . VAL D 1 166 ? -25.025 71.812  12.618 1.00 126.81 ? 174 VAL D CG2 1 
ATOM   12196 N N   . ASN D 1 167 ? -27.390 70.049  9.001  1.00 73.85  ? 175 ASN D N   1 
ATOM   12197 C CA  . ASN D 1 167 ? -27.679 69.285  7.805  1.00 85.50  ? 175 ASN D CA  1 
ATOM   12198 C C   . ASN D 1 167 ? -26.379 68.668  7.310  1.00 86.42  ? 175 ASN D C   1 
ATOM   12199 O O   . ASN D 1 167 ? -25.453 69.387  6.878  1.00 67.92  ? 175 ASN D O   1 
ATOM   12200 C CB  . ASN D 1 167 ? -28.052 70.249  6.684  1.00 109.41 ? 175 ASN D CB  1 
ATOM   12201 C CG  . ASN D 1 167 ? -28.545 69.554  5.456  1.00 81.41  ? 175 ASN D CG  1 
ATOM   12202 O OD1 . ASN D 1 167 ? -27.855 68.672  4.935  1.00 81.69  ? 175 ASN D OD1 1 
ATOM   12203 N ND2 . ASN D 1 167 ? -29.718 69.975  5.007  1.00 129.41 ? 175 ASN D ND2 1 
ATOM   12204 N N   . PRO D 1 168 ? -26.312 67.320  7.274  1.00 76.58  ? 176 PRO D N   1 
ATOM   12205 C CA  . PRO D 1 168 ? -25.047 66.654  6.963  1.00 74.98  ? 176 PRO D CA  1 
ATOM   12206 C C   . PRO D 1 168 ? -24.604 66.894  5.515  1.00 91.87  ? 176 PRO D C   1 
ATOM   12207 O O   . PRO D 1 168 ? -23.429 66.724  5.233  1.00 133.99 ? 176 PRO D O   1 
ATOM   12208 C CB  . PRO D 1 168 ? -25.206 65.173  7.408  1.00 57.41  ? 176 PRO D CB  1 
ATOM   12209 C CG  . PRO D 1 168 ? -26.656 65.068  7.863  1.00 63.56  ? 176 PRO D CG  1 
ATOM   12210 C CD  . PRO D 1 168 ? -27.420 66.385  7.511  1.00 63.43  ? 176 PRO D CD  1 
ATOM   12211 N N   . ASP D 1 169 ? -25.476 67.430  4.653  1.00 87.62  ? 177 ASP D N   1 
ATOM   12212 C CA  . ASP D 1 169 ? -24.981 67.993  3.392  1.00 84.42  ? 177 ASP D CA  1 
ATOM   12213 C C   . ASP D 1 169 ? -24.439 69.403  3.618  1.00 89.34  ? 177 ASP D C   1 
ATOM   12214 O O   . ASP D 1 169 ? -23.259 69.559  3.975  1.00 64.71  ? 177 ASP D O   1 
ATOM   12215 C CB  . ASP D 1 169 ? -26.010 67.894  2.288  1.00 68.73  ? 177 ASP D CB  1 
ATOM   12216 C CG  . ASP D 1 169 ? -26.541 66.474  2.189  1.00 96.64  ? 177 ASP D CG  1 
ATOM   12217 O OD1 . ASP D 1 169 ? -25.705 65.556  2.367  1.00 113.89 ? 177 ASP D OD1 1 
ATOM   12218 O OD2 . ASP D 1 169 ? -27.781 66.291  1.989  1.00 82.78  ? 177 ASP D OD2 1 
ATOM   12219 N N   . THR D 1 170 ? -25.343 70.384  3.517  1.00 86.89  ? 178 THR D N   1 
ATOM   12220 C CA  . THR D 1 170 ? -24.957 71.786  3.532  1.00 93.22  ? 178 THR D CA  1 
ATOM   12221 C C   . THR D 1 170 ? -23.835 72.028  4.551  1.00 112.65 ? 178 THR D C   1 
ATOM   12222 O O   . THR D 1 170 ? -22.980 72.876  4.316  1.00 103.68 ? 178 THR D O   1 
ATOM   12223 C CB  . THR D 1 170 ? -26.161 72.708  3.773  1.00 90.92  ? 178 THR D CB  1 
ATOM   12224 O OG1 . THR D 1 170 ? -26.684 72.670  5.089  1.00 83.35  ? 178 THR D OG1 1 
ATOM   12225 C CG2 . THR D 1 170 ? -27.435 72.327  3.056  1.00 76.20  ? 178 THR D CG2 1 
ATOM   12226 N N   . GLY D 1 171 ? -23.834 71.326  5.694  1.00 101.96 ? 179 GLY D N   1 
ATOM   12227 C CA  . GLY D 1 171 ? -22.906 71.652  6.774  1.00 104.18 ? 179 GLY D CA  1 
ATOM   12228 C C   . GLY D 1 171 ? -23.451 72.756  7.674  1.00 101.82 ? 179 GLY D C   1 
ATOM   12229 O O   . GLY D 1 171 ? -22.816 73.082  8.682  1.00 84.91  ? 179 GLY D O   1 
ATOM   12230 N N   . TYR D 1 172 ? -24.677 73.202  7.379  1.00 97.51  ? 180 TYR D N   1 
ATOM   12231 C CA  . TYR D 1 172 ? -25.356 74.264  8.112  1.00 83.23  ? 180 TYR D CA  1 
ATOM   12232 C C   . TYR D 1 172 ? -26.370 73.685  9.083  1.00 83.46  ? 180 TYR D C   1 
ATOM   12233 O O   . TYR D 1 172 ? -26.843 72.571  8.959  1.00 84.01  ? 180 TYR D O   1 
ATOM   12234 C CB  . TYR D 1 172 ? -26.126 75.206  7.179  1.00 67.00  ? 180 TYR D CB  1 
ATOM   12235 C CG  . TYR D 1 172 ? -25.218 76.152  6.406  1.00 71.50  ? 180 TYR D CG  1 
ATOM   12236 C CD1 . TYR D 1 172 ? -24.615 75.747  5.218  1.00 73.72  ? 180 TYR D CD1 1 
ATOM   12237 C CD2 . TYR D 1 172 ? -24.934 77.422  6.867  1.00 68.90  ? 180 TYR D CD2 1 
ATOM   12238 C CE1 . TYR D 1 172 ? -23.803 76.592  4.466  1.00 67.84  ? 180 TYR D CE1 1 
ATOM   12239 C CE2 . TYR D 1 172 ? -24.112 78.269  6.140  1.00 79.59  ? 180 TYR D CE2 1 
ATOM   12240 C CZ  . TYR D 1 172 ? -23.544 77.859  4.944  1.00 75.81  ? 180 TYR D CZ  1 
ATOM   12241 O OH  . TYR D 1 172 ? -22.683 78.696  4.299  1.00 54.68  ? 180 TYR D OH  1 
ATOM   12242 N N   . ILE D 1 173 ? -26.745 74.486  10.063 1.00 94.72  ? 181 ILE D N   1 
ATOM   12243 C CA  . ILE D 1 173 ? -27.775 74.105  11.013 1.00 82.46  ? 181 ILE D CA  1 
ATOM   12244 C C   . ILE D 1 173 ? -29.057 73.977  10.210 1.00 74.67  ? 181 ILE D C   1 
ATOM   12245 O O   . ILE D 1 173 ? -29.354 74.861  9.399  1.00 88.15  ? 181 ILE D O   1 
ATOM   12246 C CB  . ILE D 1 173 ? -27.890 75.197  12.091 1.00 70.11  ? 181 ILE D CB  1 
ATOM   12247 C CG1 . ILE D 1 173 ? -26.712 75.176  13.032 1.00 102.42 ? 181 ILE D CG1 1 
ATOM   12248 C CG2 . ILE D 1 173 ? -29.159 75.026  12.871 1.00 74.29  ? 181 ILE D CG2 1 
ATOM   12249 C CD1 . ILE D 1 173 ? -26.580 76.406  13.904 1.00 130.24 ? 181 ILE D CD1 1 
ATOM   12250 N N   . ASN D 1 174 ? -29.795 72.898  10.475 1.00 70.48  ? 182 ASN D N   1 
ATOM   12251 C CA  . ASN D 1 174 ? -31.070 72.675  9.821  1.00 69.19  ? 182 ASN D CA  1 
ATOM   12252 C C   . ASN D 1 174 ? -32.207 73.310  10.612 1.00 71.63  ? 182 ASN D C   1 
ATOM   12253 O O   . ASN D 1 174 ? -32.920 72.592  11.321 1.00 69.47  ? 182 ASN D O   1 
ATOM   12254 C CB  . ASN D 1 174 ? -31.276 71.209  9.512  1.00 76.55  ? 182 ASN D CB  1 
ATOM   12255 C CG  . ASN D 1 174 ? -32.349 71.209  8.473  1.00 102.23 ? 182 ASN D CG  1 
ATOM   12256 O OD1 . ASN D 1 174 ? -33.491 71.372  8.907  1.00 80.12  ? 182 ASN D OD1 1 
ATOM   12257 N ND2 . ASN D 1 174 ? -31.972 71.403  7.204  1.00 145.48 ? 182 ASN D ND2 1 
ATOM   12258 N N   . TYR D 1 175 ? -32.330 74.642  10.453 1.00 77.91  ? 183 TYR D N   1 
ATOM   12259 C CA  . TYR D 1 175 ? -33.273 75.418  11.235 1.00 91.94  ? 183 TYR D CA  1 
ATOM   12260 C C   . TYR D 1 175 ? -34.693 74.930  10.963 1.00 95.96  ? 183 TYR D C   1 
ATOM   12261 O O   . TYR D 1 175 ? -35.549 75.113  11.824 1.00 84.63  ? 183 TYR D O   1 
ATOM   12262 C CB  . TYR D 1 175 ? -33.164 76.928  10.994 1.00 77.47  ? 183 TYR D CB  1 
ATOM   12263 C CG  . TYR D 1 175 ? -31.799 77.529  11.307 1.00 70.14  ? 183 TYR D CG  1 
ATOM   12264 C CD1 . TYR D 1 175 ? -31.493 78.015  12.557 1.00 69.12  ? 183 TYR D CD1 1 
ATOM   12265 C CD2 . TYR D 1 175 ? -30.824 77.651  10.327 1.00 91.71  ? 183 TYR D CD2 1 
ATOM   12266 C CE1 . TYR D 1 175 ? -30.245 78.566  12.827 1.00 96.13  ? 183 TYR D CE1 1 
ATOM   12267 C CE2 . TYR D 1 175 ? -29.589 78.236  10.571 1.00 110.81 ? 183 TYR D CE2 1 
ATOM   12268 C CZ  . TYR D 1 175 ? -29.291 78.707  11.834 1.00 106.92 ? 183 TYR D CZ  1 
ATOM   12269 O OH  . TYR D 1 175 ? -28.042 79.237  12.065 1.00 83.75  ? 183 TYR D OH  1 
ATOM   12270 N N   . ASP D 1 176 ? -34.934 74.281  9.816  1.00 84.19  ? 184 ASP D N   1 
ATOM   12271 C CA  . ASP D 1 176 ? -36.316 73.884  9.547  1.00 81.65  ? 184 ASP D CA  1 
ATOM   12272 C C   . ASP D 1 176 ? -36.705 72.701  10.427 1.00 76.55  ? 184 ASP D C   1 
ATOM   12273 O O   . ASP D 1 176 ? -37.814 72.648  10.991 1.00 66.41  ? 184 ASP D O   1 
ATOM   12274 C CB  . ASP D 1 176 ? -36.619 73.555  8.094  1.00 88.14  ? 184 ASP D CB  1 
ATOM   12275 C CG  . ASP D 1 176 ? -36.043 74.505  7.069  1.00 104.22 ? 184 ASP D CG  1 
ATOM   12276 O OD1 . ASP D 1 176 ? -35.679 75.637  7.426  1.00 136.14 ? 184 ASP D OD1 1 
ATOM   12277 O OD2 . ASP D 1 176 ? -35.929 74.087  5.943  1.00 97.39  ? 184 ASP D OD2 1 
ATOM   12278 N N   . GLN D 1 177 ? -35.791 71.729  10.526 1.00 83.32  ? 185 GLN D N   1 
ATOM   12279 C CA  . GLN D 1 177 ? -36.077 70.567  11.349 1.00 76.73  ? 185 GLN D CA  1 
ATOM   12280 C C   . GLN D 1 177 ? -36.293 71.072  12.786 1.00 76.20  ? 185 GLN D C   1 
ATOM   12281 O O   . GLN D 1 177 ? -37.275 70.677  13.424 1.00 50.44  ? 185 GLN D O   1 
ATOM   12282 C CB  . GLN D 1 177 ? -35.082 69.424  11.106 1.00 50.34  ? 185 GLN D CB  1 
ATOM   12283 C CG  . GLN D 1 177 ? -35.106 68.324  12.169 1.00 42.38  ? 185 GLN D CG  1 
ATOM   12284 C CD  . GLN D 1 177 ? -33.708 68.002  12.673 1.00 73.13  ? 185 GLN D CD  1 
ATOM   12285 O OE1 . GLN D 1 177 ? -32.910 68.893  13.037 1.00 99.37  ? 185 GLN D OE1 1 
ATOM   12286 N NE2 . GLN D 1 177 ? -33.399 66.711  12.654 1.00 64.03  ? 185 GLN D NE2 1 
ATOM   12287 N N   . LEU D 1 178 ? -35.453 72.044  13.210 1.00 62.80  ? 186 LEU D N   1 
ATOM   12288 C CA  . LEU D 1 178 ? -35.520 72.642  14.528 1.00 61.00  ? 186 LEU D CA  1 
ATOM   12289 C C   . LEU D 1 178 ? -36.944 73.114  14.772 1.00 58.19  ? 186 LEU D C   1 
ATOM   12290 O O   . LEU D 1 178 ? -37.536 72.779  15.791 1.00 41.22  ? 186 LEU D O   1 
ATOM   12291 C CB  . LEU D 1 178 ? -34.504 73.765  14.750 1.00 64.08  ? 186 LEU D CB  1 
ATOM   12292 C CG  . LEU D 1 178 ? -34.635 74.553  16.074 1.00 66.85  ? 186 LEU D CG  1 
ATOM   12293 C CD1 . LEU D 1 178 ? -34.808 73.647  17.302 1.00 41.14  ? 186 LEU D CD1 1 
ATOM   12294 C CD2 . LEU D 1 178 ? -33.501 75.570  16.359 1.00 67.96  ? 186 LEU D CD2 1 
ATOM   12295 N N   . GLU D 1 179 ? -37.454 73.888  13.818 1.00 63.56  ? 187 GLU D N   1 
ATOM   12296 C CA  . GLU D 1 179 ? -38.767 74.488  13.911 1.00 74.79  ? 187 GLU D CA  1 
ATOM   12297 C C   . GLU D 1 179 ? -39.821 73.437  14.232 1.00 91.40  ? 187 GLU D C   1 
ATOM   12298 O O   . GLU D 1 179 ? -40.589 73.655  15.192 1.00 95.47  ? 187 GLU D O   1 
ATOM   12299 C CB  . GLU D 1 179 ? -39.051 75.266  12.632 1.00 66.91  ? 187 GLU D CB  1 
ATOM   12300 C CG  . GLU D 1 179 ? -40.234 76.211  12.733 1.00 70.78  ? 187 GLU D CG  1 
ATOM   12301 C CD  . GLU D 1 179 ? -40.324 76.987  11.430 1.00 80.88  ? 187 GLU D CD  1 
ATOM   12302 O OE1 . GLU D 1 179 ? -39.334 77.711  11.050 1.00 55.02  ? 187 GLU D OE1 1 
ATOM   12303 O OE2 . GLU D 1 179 ? -41.414 76.840  10.800 1.00 92.78  ? 187 GLU D OE2 1 
ATOM   12304 N N   . GLU D 1 180 ? -39.813 72.336  13.437 1.00 70.54  ? 188 GLU D N   1 
ATOM   12305 C CA  . GLU D 1 180 ? -40.823 71.272  13.530 1.00 87.13  ? 188 GLU D CA  1 
ATOM   12306 C C   . GLU D 1 180 ? -40.704 70.579  14.892 1.00 83.78  ? 188 GLU D C   1 
ATOM   12307 O O   . GLU D 1 180 ? -41.672 70.384  15.631 1.00 54.89  ? 188 GLU D O   1 
ATOM   12308 C CB  . GLU D 1 180 ? -40.789 70.242  12.389 1.00 77.97  ? 188 GLU D CB  1 
ATOM   12309 C CG  . GLU D 1 180 ? -41.134 70.893  11.057 1.00 116.70 ? 188 GLU D CG  1 
ATOM   12310 C CD  . GLU D 1 180 ? -40.349 70.644  9.772  1.00 116.66 ? 188 GLU D CD  1 
ATOM   12311 O OE1 . GLU D 1 180 ? -39.449 69.754  9.799  1.00 91.62  ? 188 GLU D OE1 1 
ATOM   12312 O OE2 . GLU D 1 180 ? -40.636 71.394  8.771  1.00 77.91  ? 188 GLU D OE2 1 
ATOM   12313 N N   . ASN D 1 181 ? -39.470 70.211  15.240 1.00 64.00  ? 189 ASN D N   1 
ATOM   12314 C CA  . ASN D 1 181 ? -39.175 69.480  16.450 1.00 59.99  ? 189 ASN D CA  1 
ATOM   12315 C C   . ASN D 1 181 ? -39.509 70.327  17.669 1.00 84.29  ? 189 ASN D C   1 
ATOM   12316 O O   . ASN D 1 181 ? -40.039 69.806  18.649 1.00 87.18  ? 189 ASN D O   1 
ATOM   12317 C CB  . ASN D 1 181 ? -37.777 68.880  16.338 1.00 61.75  ? 189 ASN D CB  1 
ATOM   12318 C CG  . ASN D 1 181 ? -37.912 67.541  15.622 1.00 82.00  ? 189 ASN D CG  1 
ATOM   12319 O OD1 . ASN D 1 181 ? -39.005 66.968  15.719 1.00 56.67  ? 189 ASN D OD1 1 
ATOM   12320 N ND2 . ASN D 1 181 ? -36.914 67.011  14.898 1.00 95.40  ? 189 ASN D ND2 1 
ATOM   12321 N N   . ALA D 1 182 ? -39.151 71.615  17.622 1.00 81.30  ? 190 ALA D N   1 
ATOM   12322 C CA  . ALA D 1 182 ? -39.421 72.522  18.735 1.00 77.50  ? 190 ALA D CA  1 
ATOM   12323 C C   . ALA D 1 182 ? -40.914 72.510  19.032 1.00 88.76  ? 190 ALA D C   1 
ATOM   12324 O O   . ALA D 1 182 ? -41.289 72.478  20.198 1.00 121.09 ? 190 ALA D O   1 
ATOM   12325 C CB  . ALA D 1 182 ? -38.940 73.927  18.451 1.00 86.08  ? 190 ALA D CB  1 
ATOM   12326 N N   . ARG D 1 183 ? -41.761 72.428  17.997 1.00 86.16  ? 191 ARG D N   1 
ATOM   12327 C CA  . ARG D 1 183 ? -43.203 72.416  18.219 1.00 70.23  ? 191 ARG D CA  1 
ATOM   12328 C C   . ARG D 1 183 ? -43.664 71.142  18.916 1.00 57.95  ? 191 ARG D C   1 
ATOM   12329 O O   . ARG D 1 183 ? -44.675 71.190  19.616 1.00 74.45  ? 191 ARG D O   1 
ATOM   12330 C CB  . ARG D 1 183 ? -44.056 72.562  16.958 1.00 70.07  ? 191 ARG D CB  1 
ATOM   12331 C CG  . ARG D 1 183 ? -43.678 73.780  16.140 1.00 61.75  ? 191 ARG D CG  1 
ATOM   12332 C CD  . ARG D 1 183 ? -44.698 73.829  14.972 1.00 58.08  ? 191 ARG D CD  1 
ATOM   12333 N NE  . ARG D 1 183 ? -44.178 73.625  13.614 1.00 71.15  ? 191 ARG D NE  1 
ATOM   12334 C CZ  . ARG D 1 183 ? -43.494 74.560  12.921 1.00 99.44  ? 191 ARG D CZ  1 
ATOM   12335 N NH1 . ARG D 1 183 ? -42.844 74.196  11.820 1.00 104.63 ? 191 ARG D NH1 1 
ATOM   12336 N NH2 . ARG D 1 183 ? -43.323 75.812  13.401 1.00 62.64  ? 191 ARG D NH2 1 
ATOM   12337 N N   . LEU D 1 184 ? -42.931 70.031  18.716 1.00 44.40  ? 192 LEU D N   1 
ATOM   12338 C CA  . LEU D 1 184 ? -43.244 68.767  19.375 1.00 67.98  ? 192 LEU D CA  1 
ATOM   12339 C C   . LEU D 1 184 ? -42.699 68.661  20.801 1.00 78.56  ? 192 LEU D C   1 
ATOM   12340 O O   . LEU D 1 184 ? -43.391 68.146  21.675 1.00 64.42  ? 192 LEU D O   1 
ATOM   12341 C CB  . LEU D 1 184 ? -42.742 67.637  18.487 1.00 63.37  ? 192 LEU D CB  1 
ATOM   12342 C CG  . LEU D 1 184 ? -43.449 67.583  17.129 1.00 49.71  ? 192 LEU D CG  1 
ATOM   12343 C CD1 . LEU D 1 184 ? -43.275 66.315  16.273 1.00 40.51  ? 192 LEU D CD1 1 
ATOM   12344 C CD2 . LEU D 1 184 ? -44.921 67.785  17.491 1.00 54.32  ? 192 LEU D CD2 1 
ATOM   12345 N N   . PHE D 1 185 ? -41.452 69.107  21.001 1.00 83.41  ? 193 PHE D N   1 
ATOM   12346 C CA  . PHE D 1 185 ? -40.762 69.018  22.281 1.00 82.64  ? 193 PHE D CA  1 
ATOM   12347 C C   . PHE D 1 185 ? -41.153 70.132  23.269 1.00 79.14  ? 193 PHE D C   1 
ATOM   12348 O O   . PHE D 1 185 ? -41.022 69.905  24.477 1.00 62.46  ? 193 PHE D O   1 
ATOM   12349 C CB  . PHE D 1 185 ? -39.270 69.106  21.962 1.00 84.43  ? 193 PHE D CB  1 
ATOM   12350 C CG  . PHE D 1 185 ? -38.328 68.932  23.149 1.00 82.93  ? 193 PHE D CG  1 
ATOM   12351 C CD1 . PHE D 1 185 ? -38.275 67.717  23.819 1.00 94.13  ? 193 PHE D CD1 1 
ATOM   12352 C CD2 . PHE D 1 185 ? -37.452 69.944  23.543 1.00 100.10 ? 193 PHE D CD2 1 
ATOM   12353 C CE1 . PHE D 1 185 ? -37.386 67.516  24.857 1.00 108.25 ? 193 PHE D CE1 1 
ATOM   12354 C CE2 . PHE D 1 185 ? -36.568 69.716  24.601 1.00 122.03 ? 193 PHE D CE2 1 
ATOM   12355 C CZ  . PHE D 1 185 ? -36.549 68.517  25.272 1.00 103.37 ? 193 PHE D CZ  1 
ATOM   12356 N N   . HIS D 1 186 ? -41.641 71.303  22.772 1.00 74.93  ? 194 HIS D N   1 
ATOM   12357 C CA  . HIS D 1 186 ? -41.939 72.510  23.547 1.00 68.18  ? 194 HIS D CA  1 
ATOM   12358 C C   . HIS D 1 186 ? -40.753 72.907  24.441 1.00 62.27  ? 194 HIS D C   1 
ATOM   12359 O O   . HIS D 1 186 ? -40.751 72.690  25.664 1.00 83.27  ? 194 HIS D O   1 
ATOM   12360 C CB  . HIS D 1 186 ? -43.198 72.310  24.395 1.00 64.25  ? 194 HIS D CB  1 
ATOM   12361 C CG  . HIS D 1 186 ? -44.295 71.630  23.711 1.00 68.91  ? 194 HIS D CG  1 
ATOM   12362 N ND1 . HIS D 1 186 ? -45.150 72.437  23.010 1.00 107.69 ? 194 HIS D ND1 1 
ATOM   12363 C CD2 . HIS D 1 186 ? -44.785 70.399  23.625 1.00 81.16  ? 194 HIS D CD2 1 
ATOM   12364 C CE1 . HIS D 1 186 ? -46.095 71.683  22.452 1.00 120.84 ? 194 HIS D CE1 1 
ATOM   12365 N NE2 . HIS D 1 186 ? -45.875 70.438  22.802 1.00 94.26  ? 194 HIS D NE2 1 
ATOM   12366 N N   . PRO D 1 187 ? -39.641 73.415  23.873 1.00 51.39  ? 195 PRO D N   1 
ATOM   12367 C CA  . PRO D 1 187 ? -38.468 73.815  24.664 1.00 53.02  ? 195 PRO D CA  1 
ATOM   12368 C C   . PRO D 1 187 ? -38.876 75.020  25.476 1.00 46.94  ? 195 PRO D C   1 
ATOM   12369 O O   . PRO D 1 187 ? -39.736 75.750  24.981 1.00 39.44  ? 195 PRO D O   1 
ATOM   12370 C CB  . PRO D 1 187 ? -37.383 74.190  23.629 1.00 54.45  ? 195 PRO D CB  1 
ATOM   12371 C CG  . PRO D 1 187 ? -38.158 74.485  22.368 1.00 56.74  ? 195 PRO D CG  1 
ATOM   12372 C CD  . PRO D 1 187 ? -39.366 73.538  22.436 1.00 64.43  ? 195 PRO D CD  1 
ATOM   12373 N N   . LYS D 1 188 ? -38.328 75.143  26.701 1.00 46.15  ? 196 LYS D N   1 
ATOM   12374 C CA  . LYS D 1 188 ? -38.563 76.311  27.556 1.00 49.70  ? 196 LYS D CA  1 
ATOM   12375 C C   . LYS D 1 188 ? -37.538 77.367  27.142 1.00 64.61  ? 196 LYS D C   1 
ATOM   12376 O O   . LYS D 1 188 ? -37.792 78.571  27.288 1.00 57.88  ? 196 LYS D O   1 
ATOM   12377 C CB  . LYS D 1 188 ? -38.347 76.061  29.065 1.00 44.94  ? 196 LYS D CB  1 
ATOM   12378 C CG  . LYS D 1 188 ? -39.367 75.435  30.085 1.00 62.75  ? 196 LYS D CG  1 
ATOM   12379 C CD  . LYS D 1 188 ? -40.579 76.286  30.560 1.00 74.89  ? 196 LYS D CD  1 
ATOM   12380 C CE  . LYS D 1 188 ? -41.197 77.338  29.538 1.00 54.07  ? 196 LYS D CE  1 
ATOM   12381 N NZ  . LYS D 1 188 ? -41.651 76.950  28.170 1.00 29.87  ? 196 LYS D NZ  1 
ATOM   12382 N N   . LEU D 1 189 ? -36.398 76.890  26.585 1.00 69.55  ? 197 LEU D N   1 
ATOM   12383 C CA  . LEU D 1 189 ? -35.219 77.691  26.279 1.00 66.48  ? 197 LEU D CA  1 
ATOM   12384 C C   . LEU D 1 189 ? -34.444 77.050  25.122 1.00 73.70  ? 197 LEU D C   1 
ATOM   12385 O O   . LEU D 1 189 ? -34.188 75.852  25.110 1.00 102.94 ? 197 LEU D O   1 
ATOM   12386 C CB  . LEU D 1 189 ? -34.372 77.925  27.532 1.00 49.20  ? 197 LEU D CB  1 
ATOM   12387 C CG  . LEU D 1 189 ? -33.030 78.648  27.358 1.00 61.17  ? 197 LEU D CG  1 
ATOM   12388 C CD1 . LEU D 1 189 ? -32.553 79.268  28.693 1.00 62.25  ? 197 LEU D CD1 1 
ATOM   12389 C CD2 . LEU D 1 189 ? -31.871 77.832  26.767 1.00 51.47  ? 197 LEU D CD2 1 
ATOM   12390 N N   . ILE D 1 190 ? -34.017 77.865  24.148 1.00 59.34  ? 198 ILE D N   1 
ATOM   12391 C CA  . ILE D 1 190 ? -33.268 77.374  23.000 1.00 68.18  ? 198 ILE D CA  1 
ATOM   12392 C C   . ILE D 1 190 ? -31.928 78.100  22.985 1.00 74.12  ? 198 ILE D C   1 
ATOM   12393 O O   . ILE D 1 190 ? -31.887 79.343  23.036 1.00 85.92  ? 198 ILE D O   1 
ATOM   12394 C CB  . ILE D 1 190 ? -34.002 77.649  21.673 1.00 72.19  ? 198 ILE D CB  1 
ATOM   12395 C CG1 . ILE D 1 190 ? -35.361 76.986  21.586 1.00 94.58  ? 198 ILE D CG1 1 
ATOM   12396 C CG2 . ILE D 1 190 ? -33.147 77.247  20.478 1.00 72.83  ? 198 ILE D CG2 1 
ATOM   12397 C CD1 . ILE D 1 190 ? -36.176 77.411  20.368 1.00 110.59 ? 198 ILE D CD1 1 
ATOM   12398 N N   . ILE D 1 191 ? -30.850 77.317  22.817 1.00 47.84  ? 199 ILE D N   1 
ATOM   12399 C CA  . ILE D 1 191 ? -29.516 77.877  22.835 1.00 44.82  ? 199 ILE D CA  1 
ATOM   12400 C C   . ILE D 1 191 ? -29.067 78.221  21.413 1.00 72.60  ? 199 ILE D C   1 
ATOM   12401 O O   . ILE D 1 191 ? -29.116 77.392  20.502 1.00 85.44  ? 199 ILE D O   1 
ATOM   12402 C CB  . ILE D 1 191 ? -28.594 76.872  23.534 1.00 42.86  ? 199 ILE D CB  1 
ATOM   12403 C CG1 . ILE D 1 191 ? -29.033 76.644  24.939 1.00 46.97  ? 199 ILE D CG1 1 
ATOM   12404 C CG2 . ILE D 1 191 ? -27.104 77.235  23.510 1.00 50.61  ? 199 ILE D CG2 1 
ATOM   12405 C CD1 . ILE D 1 191 ? -28.335 75.435  25.545 1.00 53.99  ? 199 ILE D CD1 1 
ATOM   12406 N N   . ALA D 1 192 ? -28.545 79.443  21.249 1.00 89.73  ? 200 ALA D N   1 
ATOM   12407 C CA  . ALA D 1 192 ? -28.008 79.916  19.984 1.00 84.05  ? 200 ALA D CA  1 
ATOM   12408 C C   . ALA D 1 192 ? -26.505 80.141  20.164 1.00 97.38  ? 200 ALA D C   1 
ATOM   12409 O O   . ALA D 1 192 ? -26.052 81.199  20.616 1.00 85.95  ? 200 ALA D O   1 
ATOM   12410 C CB  . ALA D 1 192 ? -28.730 81.187  19.596 1.00 89.08  ? 200 ALA D CB  1 
ATOM   12411 N N   . GLY D 1 193 ? -25.735 79.089  19.866 1.00 107.61 ? 201 GLY D N   1 
ATOM   12412 C CA  . GLY D 1 193 ? -24.337 79.052  20.289 1.00 85.11  ? 201 GLY D CA  1 
ATOM   12413 C C   . GLY D 1 193 ? -23.724 77.717  19.911 1.00 83.23  ? 201 GLY D C   1 
ATOM   12414 O O   . GLY D 1 193 ? -24.429 76.700  19.932 1.00 109.69 ? 201 GLY D O   1 
ATOM   12415 N N   . THR D 1 194 ? -22.435 77.750  19.538 1.00 69.44  ? 202 THR D N   1 
ATOM   12416 C CA  . THR D 1 194 ? -21.733 76.547  19.079 1.00 66.38  ? 202 THR D CA  1 
ATOM   12417 C C   . THR D 1 194 ? -20.328 76.485  19.681 1.00 68.41  ? 202 THR D C   1 
ATOM   12418 O O   . THR D 1 194 ? -19.776 77.500  20.163 1.00 66.98  ? 202 THR D O   1 
ATOM   12419 C CB  . THR D 1 194 ? -21.662 76.491  17.545 1.00 81.16  ? 202 THR D CB  1 
ATOM   12420 O OG1 . THR D 1 194 ? -20.758 77.515  17.133 1.00 65.05  ? 202 THR D OG1 1 
ATOM   12421 C CG2 . THR D 1 194 ? -22.999 76.740  16.853 1.00 92.12  ? 202 THR D CG2 1 
ATOM   12422 N N   . SER D 1 195 ? -19.731 75.283  19.623 1.00 73.73  ? 203 SER D N   1 
ATOM   12423 C CA  . SER D 1 195 ? -18.319 75.176  19.955 1.00 82.58  ? 203 SER D CA  1 
ATOM   12424 C C   . SER D 1 195 ? -17.495 74.917  18.692 1.00 98.65  ? 203 SER D C   1 
ATOM   12425 O O   . SER D 1 195 ? -16.287 75.094  18.696 1.00 105.51 ? 203 SER D O   1 
ATOM   12426 C CB  . SER D 1 195 ? -18.074 74.153  20.998 1.00 69.04  ? 203 SER D CB  1 
ATOM   12427 O OG  . SER D 1 195 ? -17.027 74.682  21.809 1.00 74.82  ? 203 SER D OG  1 
ATOM   12428 N N   . CYS D 1 196 ? -18.158 74.478  17.627 1.00 116.46 ? 204 CYS D N   1 
ATOM   12429 C CA  . CYS D 1 196 ? -17.444 74.223  16.393 1.00 89.71  ? 204 CYS D CA  1 
ATOM   12430 C C   . CYS D 1 196 ? -18.387 74.396  15.205 1.00 80.70  ? 204 CYS D C   1 
ATOM   12431 O O   . CYS D 1 196 ? -19.027 73.427  14.794 1.00 78.98  ? 204 CYS D O   1 
ATOM   12432 C CB  . CYS D 1 196 ? -17.007 72.762  16.391 1.00 97.65  ? 204 CYS D CB  1 
ATOM   12433 S SG  . CYS D 1 196 ? -16.081 72.275  14.908 1.00 90.86  ? 204 CYS D SG  1 
ATOM   12434 N N   . TYR D 1 197 ? -18.497 75.622  14.688 1.00 74.13  ? 205 TYR D N   1 
ATOM   12435 C CA  . TYR D 1 197 ? -19.311 75.884  13.503 1.00 71.41  ? 205 TYR D CA  1 
ATOM   12436 C C   . TYR D 1 197 ? -18.747 77.105  12.773 1.00 96.36  ? 205 TYR D C   1 
ATOM   12437 O O   . TYR D 1 197 ? -18.428 78.120  13.373 1.00 88.88  ? 205 TYR D O   1 
ATOM   12438 C CB  . TYR D 1 197 ? -20.722 76.103  14.045 1.00 59.71  ? 205 TYR D CB  1 
ATOM   12439 C CG  . TYR D 1 197 ? -21.831 76.312  13.045 1.00 69.90  ? 205 TYR D CG  1 
ATOM   12440 C CD1 . TYR D 1 197 ? -22.330 75.242  12.310 1.00 89.86  ? 205 TYR D CD1 1 
ATOM   12441 C CD2 . TYR D 1 197 ? -22.487 77.533  12.943 1.00 76.32  ? 205 TYR D CD2 1 
ATOM   12442 C CE1 . TYR D 1 197 ? -23.414 75.402  11.449 1.00 77.77  ? 205 TYR D CE1 1 
ATOM   12443 C CE2 . TYR D 1 197 ? -23.561 77.711  12.078 1.00 82.19  ? 205 TYR D CE2 1 
ATOM   12444 C CZ  . TYR D 1 197 ? -24.002 76.655  11.312 1.00 77.84  ? 205 TYR D CZ  1 
ATOM   12445 O OH  . TYR D 1 197 ? -25.029 76.934  10.472 1.00 96.25  ? 205 TYR D OH  1 
ATOM   12446 N N   . SER D 1 198 ? -18.539 77.001  11.455 1.00 132.10 ? 206 SER D N   1 
ATOM   12447 C CA  . SER D 1 198 ? -17.774 78.009  10.724 1.00 108.51 ? 206 SER D CA  1 
ATOM   12448 C C   . SER D 1 198 ? -18.648 79.199  10.362 1.00 100.27 ? 206 SER D C   1 
ATOM   12449 O O   . SER D 1 198 ? -18.129 80.126  9.742  1.00 93.34  ? 206 SER D O   1 
ATOM   12450 C CB  . SER D 1 198 ? -17.200 77.468  9.446  1.00 93.09  ? 206 SER D CB  1 
ATOM   12451 O OG  . SER D 1 198 ? -16.399 76.295  9.586  1.00 128.23 ? 206 SER D OG  1 
ATOM   12452 N N   . ARG D 1 199 ? -19.948 79.166  10.720 1.00 90.23  ? 207 ARG D N   1 
ATOM   12453 C CA  . ARG D 1 199 ? -20.902 80.106  10.138 1.00 93.10  ? 207 ARG D CA  1 
ATOM   12454 C C   . ARG D 1 199 ? -21.607 80.923  11.206 1.00 92.07  ? 207 ARG D C   1 
ATOM   12455 O O   . ARG D 1 199 ? -21.601 80.533  12.366 1.00 80.93  ? 207 ARG D O   1 
ATOM   12456 C CB  . ARG D 1 199 ? -21.965 79.401  9.298  1.00 83.79  ? 207 ARG D CB  1 
ATOM   12457 C CG  . ARG D 1 199 ? -21.350 78.708  8.091  1.00 70.83  ? 207 ARG D CG  1 
ATOM   12458 C CD  . ARG D 1 199 ? -20.601 79.724  7.291  1.00 68.62  ? 207 ARG D CD  1 
ATOM   12459 N NE  . ARG D 1 199 ? -20.051 79.034  6.136  1.00 83.25  ? 207 ARG D NE  1 
ATOM   12460 C CZ  . ARG D 1 199 ? -19.241 79.524  5.244  1.00 72.68  ? 207 ARG D CZ  1 
ATOM   12461 N NH1 . ARG D 1 199 ? -18.581 80.653  5.493  1.00 72.60  ? 207 ARG D NH1 1 
ATOM   12462 N NH2 . ARG D 1 199 ? -18.917 78.732  4.243  1.00 47.65  ? 207 ARG D NH2 1 
ATOM   12463 N N   . ASN D 1 200 ? -22.207 82.058  10.800 1.00 77.41  ? 208 ASN D N   1 
ATOM   12464 C CA  . ASN D 1 200 ? -22.967 82.849  11.760 1.00 92.13  ? 208 ASN D CA  1 
ATOM   12465 C C   . ASN D 1 200 ? -24.297 82.153  12.032 1.00 83.71  ? 208 ASN D C   1 
ATOM   12466 O O   . ASN D 1 200 ? -24.737 81.283  11.284 1.00 90.73  ? 208 ASN D O   1 
ATOM   12467 C CB  . ASN D 1 200 ? -23.286 84.254  11.271 1.00 106.53 ? 208 ASN D CB  1 
ATOM   12468 C CG  . ASN D 1 200 ? -22.079 84.970  10.728 1.00 117.41 ? 208 ASN D CG  1 
ATOM   12469 O OD1 . ASN D 1 200 ? -20.989 84.918  11.312 1.00 115.57 ? 208 ASN D OD1 1 
ATOM   12470 N ND2 . ASN D 1 200 ? -22.212 85.502  9.523  1.00 202.11 ? 208 ASN D ND2 1 
ATOM   12471 N N   . LEU D 1 201 ? -24.956 82.509  13.122 1.00 81.56  ? 209 LEU D N   1 
ATOM   12472 C CA  . LEU D 1 201 ? -26.248 81.873  13.354 1.00 92.43  ? 209 LEU D CA  1 
ATOM   12473 C C   . LEU D 1 201 ? -27.343 82.778  12.832 1.00 73.47  ? 209 LEU D C   1 
ATOM   12474 O O   . LEU D 1 201 ? -27.252 83.984  13.071 1.00 81.15  ? 209 LEU D O   1 
ATOM   12475 C CB  . LEU D 1 201 ? -26.476 81.631  14.845 1.00 84.91  ? 209 LEU D CB  1 
ATOM   12476 C CG  . LEU D 1 201 ? -25.367 80.833  15.520 1.00 84.50  ? 209 LEU D CG  1 
ATOM   12477 C CD1 . LEU D 1 201 ? -25.719 80.749  16.963 1.00 110.58 ? 209 LEU D CD1 1 
ATOM   12478 C CD2 . LEU D 1 201 ? -25.181 79.440  14.903 1.00 89.81  ? 209 LEU D CD2 1 
ATOM   12479 N N   . GLU D 1 202 ? -28.387 82.176  12.243 1.00 66.41  ? 210 GLU D N   1 
ATOM   12480 C CA  . GLU D 1 202 ? -29.613 82.923  11.954 1.00 90.90  ? 210 GLU D CA  1 
ATOM   12481 C C   . GLU D 1 202 ? -30.342 83.281  13.263 1.00 76.93  ? 210 GLU D C   1 
ATOM   12482 O O   . GLU D 1 202 ? -31.408 82.747  13.506 1.00 60.73  ? 210 GLU D O   1 
ATOM   12483 C CB  . GLU D 1 202 ? -30.509 82.174  10.954 1.00 70.65  ? 210 GLU D CB  1 
ATOM   12484 C CG  . GLU D 1 202 ? -29.971 82.062  9.530  1.00 84.44  ? 210 GLU D CG  1 
ATOM   12485 C CD  . GLU D 1 202 ? -30.558 81.011  8.578  1.00 110.10 ? 210 GLU D CD  1 
ATOM   12486 O OE1 . GLU D 1 202 ? -31.721 81.035  8.027  1.00 105.54 ? 210 GLU D OE1 1 
ATOM   12487 O OE2 . GLU D 1 202 ? -29.750 80.070  8.365  1.00 92.44  ? 210 GLU D OE2 1 
ATOM   12488 N N   . TYR D 1 203 ? -29.786 84.145  14.130 1.00 75.79  ? 211 TYR D N   1 
ATOM   12489 C CA  . TYR D 1 203 ? -30.441 84.591  15.362 1.00 80.59  ? 211 TYR D CA  1 
ATOM   12490 C C   . TYR D 1 203 ? -31.902 85.013  15.109 1.00 94.80  ? 211 TYR D C   1 
ATOM   12491 O O   . TYR D 1 203 ? -32.836 84.564  15.799 1.00 77.09  ? 211 TYR D O   1 
ATOM   12492 C CB  . TYR D 1 203 ? -29.694 85.725  16.086 1.00 72.81  ? 211 TYR D CB  1 
ATOM   12493 C CG  . TYR D 1 203 ? -28.250 85.412  16.416 1.00 85.14  ? 211 TYR D CG  1 
ATOM   12494 C CD1 . TYR D 1 203 ? -27.950 84.458  17.368 1.00 94.40  ? 211 TYR D CD1 1 
ATOM   12495 C CD2 . TYR D 1 203 ? -27.192 86.067  15.795 1.00 118.13 ? 211 TYR D CD2 1 
ATOM   12496 C CE1 . TYR D 1 203 ? -26.644 84.138  17.694 1.00 100.50 ? 211 TYR D CE1 1 
ATOM   12497 C CE2 . TYR D 1 203 ? -25.876 85.768  16.122 1.00 119.41 ? 211 TYR D CE2 1 
ATOM   12498 C CZ  . TYR D 1 203 ? -25.607 84.799  17.071 1.00 101.28 ? 211 TYR D CZ  1 
ATOM   12499 O OH  . TYR D 1 203 ? -24.347 84.434  17.422 1.00 97.09  ? 211 TYR D OH  1 
ATOM   12500 N N   . ALA D 1 204 ? -32.093 85.916  14.142 1.00 93.63  ? 212 ALA D N   1 
ATOM   12501 C CA  . ALA D 1 204 ? -33.429 86.340  13.792 1.00 67.87  ? 212 ALA D CA  1 
ATOM   12502 C C   . ALA D 1 204 ? -34.385 85.155  13.577 1.00 81.84  ? 212 ALA D C   1 
ATOM   12503 O O   . ALA D 1 204 ? -35.467 85.168  14.153 1.00 96.07  ? 212 ALA D O   1 
ATOM   12504 C CB  . ALA D 1 204 ? -33.248 87.240  12.635 1.00 69.15  ? 212 ALA D CB  1 
ATOM   12505 N N   . ARG D 1 205 ? -33.966 84.107  12.840 1.00 74.53  ? 213 ARG D N   1 
ATOM   12506 C CA  . ARG D 1 205 ? -34.751 82.895  12.646 1.00 86.29  ? 213 ARG D CA  1 
ATOM   12507 C C   . ARG D 1 205 ? -34.944 82.123  13.945 1.00 101.71 ? 213 ARG D C   1 
ATOM   12508 O O   . ARG D 1 205 ? -36.034 81.687  14.272 1.00 112.47 ? 213 ARG D O   1 
ATOM   12509 C CB  . ARG D 1 205 ? -34.088 81.917  11.679 1.00 98.58  ? 213 ARG D CB  1 
ATOM   12510 C CG  . ARG D 1 205 ? -35.022 80.829  11.173 1.00 73.34  ? 213 ARG D CG  1 
ATOM   12511 C CD  . ARG D 1 205 ? -34.859 80.590  9.613  1.00 101.57 ? 213 ARG D CD  1 
ATOM   12512 N NE  . ARG D 1 205 ? -35.429 79.295  9.215  1.00 122.41 ? 213 ARG D NE  1 
ATOM   12513 C CZ  . ARG D 1 205 ? -36.541 78.749  9.750  1.00 148.04 ? 213 ARG D CZ  1 
ATOM   12514 N NH1 . ARG D 1 205 ? -37.258 79.374  10.694 1.00 136.36 ? 213 ARG D NH1 1 
ATOM   12515 N NH2 . ARG D 1 205 ? -36.941 77.561  9.356  1.00 113.71 ? 213 ARG D NH2 1 
ATOM   12516 N N   . LEU D 1 206 ? -33.878 81.984  14.715 1.00 90.80  ? 214 LEU D N   1 
ATOM   12517 C CA  . LEU D 1 206 ? -33.948 81.301  16.004 1.00 81.75  ? 214 LEU D CA  1 
ATOM   12518 C C   . LEU D 1 206 ? -34.963 82.005  16.887 1.00 79.52  ? 214 LEU D C   1 
ATOM   12519 O O   . LEU D 1 206 ? -35.695 81.373  17.624 1.00 89.10  ? 214 LEU D O   1 
ATOM   12520 C CB  . LEU D 1 206 ? -32.605 81.234  16.722 1.00 67.14  ? 214 LEU D CB  1 
ATOM   12521 C CG  . LEU D 1 206 ? -31.578 80.418  15.947 1.00 75.05  ? 214 LEU D CG  1 
ATOM   12522 C CD1 . LEU D 1 206 ? -30.172 80.593  16.453 1.00 79.29  ? 214 LEU D CD1 1 
ATOM   12523 C CD2 . LEU D 1 206 ? -32.059 78.962  15.891 1.00 86.37  ? 214 LEU D CD2 1 
ATOM   12524 N N   . ARG D 1 207 ? -34.994 83.325  16.801 1.00 83.73  ? 215 ARG D N   1 
ATOM   12525 C CA  . ARG D 1 207 ? -35.892 84.055  17.663 1.00 82.48  ? 215 ARG D CA  1 
ATOM   12526 C C   . ARG D 1 207 ? -37.332 83.831  17.217 1.00 93.62  ? 215 ARG D C   1 
ATOM   12527 O O   . ARG D 1 207 ? -38.199 83.670  18.104 1.00 73.64  ? 215 ARG D O   1 
ATOM   12528 C CB  . ARG D 1 207 ? -35.628 85.556  17.753 1.00 60.51  ? 215 ARG D CB  1 
ATOM   12529 C CG  . ARG D 1 207 ? -36.489 85.636  19.018 1.00 38.69  ? 215 ARG D CG  1 
ATOM   12530 C CD  . ARG D 1 207 ? -36.736 87.059  18.993 1.00 32.86  ? 215 ARG D CD  1 
ATOM   12531 N NE  . ARG D 1 207 ? -37.688 87.798  19.808 1.00 37.02  ? 215 ARG D NE  1 
ATOM   12532 C CZ  . ARG D 1 207 ? -37.186 88.038  20.967 1.00 62.88  ? 215 ARG D CZ  1 
ATOM   12533 N NH1 . ARG D 1 207 ? -37.146 86.963  21.767 1.00 56.02  ? 215 ARG D NH1 1 
ATOM   12534 N NH2 . ARG D 1 207 ? -36.785 89.319  21.260 1.00 54.73  ? 215 ARG D NH2 1 
ATOM   12535 N N   . LYS D 1 208 ? -37.575 83.850  15.883 1.00 72.45  ? 216 LYS D N   1 
ATOM   12536 C CA  . LYS D 1 208 ? -38.882 83.458  15.342 1.00 83.15  ? 216 LYS D CA  1 
ATOM   12537 C C   . LYS D 1 208 ? -39.311 82.142  16.029 1.00 94.50  ? 216 LYS D C   1 
ATOM   12538 O O   . LYS D 1 208 ? -40.322 82.095  16.774 1.00 74.99  ? 216 LYS D O   1 
ATOM   12539 C CB  . LYS D 1 208 ? -38.937 83.440  13.800 1.00 62.99  ? 216 LYS D CB  1 
ATOM   12540 C CG  . LYS D 1 208 ? -38.180 84.549  12.942 1.00 93.55  ? 216 LYS D CG  1 
ATOM   12541 C CD  . LYS D 1 208 ? -37.778 84.389  11.440 1.00 90.49  ? 216 LYS D CD  1 
ATOM   12542 C CE  . LYS D 1 208 ? -37.068 85.427  10.487 1.00 65.02  ? 216 LYS D CE  1 
ATOM   12543 N NZ  . LYS D 1 208 ? -36.731 85.063  9.102  1.00 27.18  ? 216 LYS D NZ  1 
ATOM   12544 N N   . ILE D 1 209 ? -38.420 81.135  15.917 1.00 71.61  ? 217 ILE D N   1 
ATOM   12545 C CA  . ILE D 1 209 ? -38.711 79.801  16.429 1.00 77.73  ? 217 ILE D CA  1 
ATOM   12546 C C   . ILE D 1 209 ? -39.043 79.814  17.913 1.00 78.07  ? 217 ILE D C   1 
ATOM   12547 O O   . ILE D 1 209 ? -39.941 79.091  18.315 1.00 58.58  ? 217 ILE D O   1 
ATOM   12548 C CB  . ILE D 1 209 ? -37.565 78.793  16.246 1.00 78.06  ? 217 ILE D CB  1 
ATOM   12549 C CG1 . ILE D 1 209 ? -36.793 78.973  14.934 1.00 69.95  ? 217 ILE D CG1 1 
ATOM   12550 C CG2 . ILE D 1 209 ? -38.087 77.372  16.517 1.00 69.78  ? 217 ILE D CG2 1 
ATOM   12551 C CD1 . ILE D 1 209 ? -36.354 77.675  14.264 1.00 83.97  ? 217 ILE D CD1 1 
ATOM   12552 N N   . ALA D 1 210 ? -38.216 80.530  18.695 1.00 68.81  ? 218 ALA D N   1 
ATOM   12553 C CA  . ALA D 1 210 ? -38.362 80.585  20.131 1.00 71.59  ? 218 ALA D CA  1 
ATOM   12554 C C   . ALA D 1 210 ? -39.702 81.231  20.460 1.00 81.83  ? 218 ALA D C   1 
ATOM   12555 O O   . ALA D 1 210 ? -40.502 80.626  21.197 1.00 64.91  ? 218 ALA D O   1 
ATOM   12556 C CB  . ALA D 1 210 ? -37.199 81.315  20.754 1.00 67.12  ? 218 ALA D CB  1 
ATOM   12557 N N   . ASP D 1 211 ? -39.969 82.416  19.865 1.00 73.81  ? 219 ASP D N   1 
ATOM   12558 C CA  . ASP D 1 211 ? -41.197 83.121  20.209 1.00 76.64  ? 219 ASP D CA  1 
ATOM   12559 C C   . ASP D 1 211 ? -42.375 82.228  19.848 1.00 63.03  ? 219 ASP D C   1 
ATOM   12560 O O   . ASP D 1 211 ? -43.341 82.164  20.586 1.00 67.69  ? 219 ASP D O   1 
ATOM   12561 C CB  . ASP D 1 211 ? -41.374 84.442  19.488 1.00 70.35  ? 219 ASP D CB  1 
ATOM   12562 C CG  . ASP D 1 211 ? -40.352 85.518  19.806 1.00 78.86  ? 219 ASP D CG  1 
ATOM   12563 O OD1 . ASP D 1 211 ? -39.910 85.679  20.975 1.00 65.52  ? 219 ASP D OD1 1 
ATOM   12564 O OD2 . ASP D 1 211 ? -40.038 86.226  18.868 1.00 82.43  ? 219 ASP D OD2 1 
ATOM   12565 N N   . GLU D 1 212 ? -42.258 81.505  18.733 1.00 49.64  ? 220 GLU D N   1 
ATOM   12566 C CA  . GLU D 1 212 ? -43.359 80.670  18.290 1.00 61.09  ? 220 GLU D CA  1 
ATOM   12567 C C   . GLU D 1 212 ? -43.690 79.636  19.358 1.00 54.37  ? 220 GLU D C   1 
ATOM   12568 O O   . GLU D 1 212 ? -44.831 79.225  19.417 1.00 58.42  ? 220 GLU D O   1 
ATOM   12569 C CB  . GLU D 1 212 ? -43.048 80.010  16.937 1.00 79.99  ? 220 GLU D CB  1 
ATOM   12570 C CG  . GLU D 1 212 ? -44.235 79.287  16.303 1.00 77.93  ? 220 GLU D CG  1 
ATOM   12571 C CD  . GLU D 1 212 ? -43.966 77.886  15.769 1.00 101.51 ? 220 GLU D CD  1 
ATOM   12572 O OE1 . GLU D 1 212 ? -42.776 77.442  15.576 1.00 109.08 ? 220 GLU D OE1 1 
ATOM   12573 O OE2 . GLU D 1 212 ? -45.031 77.219  15.638 1.00 78.30  ? 220 GLU D OE2 1 
ATOM   12574 N N   . ASN D 1 213 ? -42.687 79.194  20.139 1.00 56.10  ? 221 ASN D N   1 
ATOM   12575 C CA  . ASN D 1 213 ? -42.844 78.114  21.093 1.00 57.61  ? 221 ASN D CA  1 
ATOM   12576 C C   . ASN D 1 213 ? -42.858 78.632  22.523 1.00 62.28  ? 221 ASN D C   1 
ATOM   12577 O O   . ASN D 1 213 ? -42.961 77.817  23.443 1.00 71.62  ? 221 ASN D O   1 
ATOM   12578 C CB  . ASN D 1 213 ? -41.712 77.121  20.949 1.00 61.63  ? 221 ASN D CB  1 
ATOM   12579 C CG  . ASN D 1 213 ? -41.918 76.294  19.709 1.00 75.11  ? 221 ASN D CG  1 
ATOM   12580 O OD1 . ASN D 1 213 ? -42.661 75.317  19.789 1.00 84.46  ? 221 ASN D OD1 1 
ATOM   12581 N ND2 . ASN D 1 213 ? -41.267 76.629  18.599 1.00 81.40  ? 221 ASN D ND2 1 
ATOM   12582 N N   . GLY D 1 214 ? -42.770 79.964  22.671 1.00 54.23  ? 222 GLY D N   1 
ATOM   12583 C CA  . GLY D 1 214 ? -42.913 80.608  23.962 1.00 54.68  ? 222 GLY D CA  1 
ATOM   12584 C C   . GLY D 1 214 ? -41.669 80.343  24.786 1.00 59.89  ? 222 GLY D C   1 
ATOM   12585 O O   . GLY D 1 214 ? -41.686 80.423  26.000 1.00 62.76  ? 222 GLY D O   1 
ATOM   12586 N N   . ALA D 1 215 ? -40.562 80.047  24.112 1.00 64.26  ? 223 ALA D N   1 
ATOM   12587 C CA  . ALA D 1 215 ? -39.322 79.751  24.803 1.00 62.26  ? 223 ALA D CA  1 
ATOM   12588 C C   . ALA D 1 215 ? -38.437 80.974  24.757 1.00 69.12  ? 223 ALA D C   1 
ATOM   12589 O O   . ALA D 1 215 ? -38.638 81.873  23.948 1.00 64.15  ? 223 ALA D O   1 
ATOM   12590 C CB  . ALA D 1 215 ? -38.602 78.623  24.104 1.00 86.60  ? 223 ALA D CB  1 
ATOM   12591 N N   . TYR D 1 216 ? -37.424 80.933  25.616 1.00 77.19  ? 224 TYR D N   1 
ATOM   12592 C CA  . TYR D 1 216 ? -36.391 81.945  25.657 1.00 75.14  ? 224 TYR D CA  1 
ATOM   12593 C C   . TYR D 1 216 ? -35.346 81.644  24.595 1.00 84.19  ? 224 TYR D C   1 
ATOM   12594 O O   . TYR D 1 216 ? -35.091 80.475  24.326 1.00 134.22 ? 224 TYR D O   1 
ATOM   12595 C CB  . TYR D 1 216 ? -35.695 81.765  26.997 1.00 59.56  ? 224 TYR D CB  1 
ATOM   12596 C CG  . TYR D 1 216 ? -36.396 82.428  28.162 1.00 64.82  ? 224 TYR D CG  1 
ATOM   12597 C CD1 . TYR D 1 216 ? -36.779 83.774  28.169 1.00 57.37  ? 224 TYR D CD1 1 
ATOM   12598 C CD2 . TYR D 1 216 ? -36.642 81.677  29.294 1.00 76.83  ? 224 TYR D CD2 1 
ATOM   12599 C CE1 . TYR D 1 216 ? -37.396 84.334  29.272 1.00 50.29  ? 224 TYR D CE1 1 
ATOM   12600 C CE2 . TYR D 1 216 ? -37.244 82.233  30.416 1.00 70.04  ? 224 TYR D CE2 1 
ATOM   12601 C CZ  . TYR D 1 216 ? -37.638 83.555  30.390 1.00 56.12  ? 224 TYR D CZ  1 
ATOM   12602 O OH  . TYR D 1 216 ? -38.238 84.046  31.499 1.00 48.24  ? 224 TYR D OH  1 
ATOM   12603 N N   . LEU D 1 217 ? -34.712 82.687  24.043 1.00 63.46  ? 225 LEU D N   1 
ATOM   12604 C CA  . LEU D 1 217 ? -33.573 82.470  23.161 1.00 67.30  ? 225 LEU D CA  1 
ATOM   12605 C C   . LEU D 1 217 ? -32.307 82.917  23.871 1.00 77.14  ? 225 LEU D C   1 
ATOM   12606 O O   . LEU D 1 217 ? -32.091 84.100  24.103 1.00 90.00  ? 225 LEU D O   1 
ATOM   12607 C CB  . LEU D 1 217 ? -33.740 83.210  21.846 1.00 58.63  ? 225 LEU D CB  1 
ATOM   12608 C CG  . LEU D 1 217 ? -32.613 83.006  20.847 1.00 57.71  ? 225 LEU D CG  1 
ATOM   12609 C CD1 . LEU D 1 217 ? -32.821 81.601  20.363 1.00 69.82  ? 225 LEU D CD1 1 
ATOM   12610 C CD2 . LEU D 1 217 ? -32.707 84.067  19.728 1.00 62.05  ? 225 LEU D CD2 1 
ATOM   12611 N N   . MET D 1 218 ? -31.516 81.941  24.278 1.00 92.31  ? 226 MET D N   1 
ATOM   12612 C CA  . MET D 1 218 ? -30.277 82.235  24.978 1.00 85.47  ? 226 MET D CA  1 
ATOM   12613 C C   . MET D 1 218 ? -29.114 81.982  24.019 1.00 78.29  ? 226 MET D C   1 
ATOM   12614 O O   . MET D 1 218 ? -28.951 80.892  23.448 1.00 71.18  ? 226 MET D O   1 
ATOM   12615 C CB  . MET D 1 218 ? -30.080 81.325  26.203 1.00 80.69  ? 226 MET D CB  1 
ATOM   12616 C CG  . MET D 1 218 ? -28.765 81.645  26.875 1.00 80.45  ? 226 MET D CG  1 
ATOM   12617 S SD  . MET D 1 218 ? -27.914 80.290  27.689 1.00 83.98  ? 226 MET D SD  1 
ATOM   12618 C CE  . MET D 1 218 ? -26.646 79.881  26.480 1.00 107.90 ? 226 MET D CE  1 
ATOM   12619 N N   . ALA D 1 219 ? -28.280 82.998  23.858 1.00 59.96  ? 227 ALA D N   1 
ATOM   12620 C CA  . ALA D 1 219 ? -27.140 82.846  22.970 1.00 79.87  ? 227 ALA D CA  1 
ATOM   12621 C C   . ALA D 1 219 ? -25.924 82.514  23.819 1.00 101.10 ? 227 ALA D C   1 
ATOM   12622 O O   . ALA D 1 219 ? -25.777 83.120  24.885 1.00 99.65  ? 227 ALA D O   1 
ATOM   12623 C CB  . ALA D 1 219 ? -26.923 84.144  22.230 1.00 82.63  ? 227 ALA D CB  1 
ATOM   12624 N N   . ASP D 1 220 ? -25.101 81.557  23.351 1.00 90.59  ? 228 ASP D N   1 
ATOM   12625 C CA  . ASP D 1 220 ? -23.805 81.299  23.973 1.00 82.65  ? 228 ASP D CA  1 
ATOM   12626 C C   . ASP D 1 220 ? -22.743 81.755  22.983 1.00 74.41  ? 228 ASP D C   1 
ATOM   12627 O O   . ASP D 1 220 ? -22.394 81.026  22.057 1.00 95.44  ? 228 ASP D O   1 
ATOM   12628 C CB  . ASP D 1 220 ? -23.639 79.866  24.465 1.00 85.68  ? 228 ASP D CB  1 
ATOM   12629 C CG  . ASP D 1 220 ? -22.346 79.515  25.201 1.00 82.49  ? 228 ASP D CG  1 
ATOM   12630 O OD1 . ASP D 1 220 ? -21.414 80.303  25.178 1.00 91.50  ? 228 ASP D OD1 1 
ATOM   12631 O OD2 . ASP D 1 220 ? -22.290 78.472  25.864 1.00 67.34  ? 228 ASP D OD2 1 
ATOM   12632 N N   . MET D 1 221 ? -22.229 82.965  23.202 1.00 77.69  ? 229 MET D N   1 
ATOM   12633 C CA  . MET D 1 221 ? -21.313 83.573  22.245 1.00 89.96  ? 229 MET D CA  1 
ATOM   12634 C C   . MET D 1 221 ? -19.863 83.333  22.662 1.00 116.88 ? 229 MET D C   1 
ATOM   12635 O O   . MET D 1 221 ? -18.986 84.054  22.184 1.00 100.33 ? 229 MET D O   1 
ATOM   12636 C CB  . MET D 1 221 ? -21.547 85.086  22.111 1.00 60.87  ? 229 MET D CB  1 
ATOM   12637 C CG  . MET D 1 221 ? -21.289 85.884  23.386 1.00 63.83  ? 229 MET D CG  1 
ATOM   12638 S SD  . MET D 1 221 ? -21.704 87.605  23.049 1.00 78.10  ? 229 MET D SD  1 
ATOM   12639 C CE  . MET D 1 221 ? -20.298 87.767  21.939 1.00 119.68 ? 229 MET D CE  1 
ATOM   12640 N N   . ALA D 1 222 ? -19.619 82.331  23.529 1.00 129.50 ? 230 ALA D N   1 
ATOM   12641 C CA  . ALA D 1 222 ? -18.301 82.056  24.090 1.00 105.74 ? 230 ALA D CA  1 
ATOM   12642 C C   . ALA D 1 222 ? -17.229 82.073  23.017 1.00 86.81  ? 230 ALA D C   1 
ATOM   12643 O O   . ALA D 1 222 ? -16.192 82.694  23.245 1.00 86.59  ? 230 ALA D O   1 
ATOM   12644 C CB  . ALA D 1 222 ? -18.271 80.731  24.791 1.00 119.05 ? 230 ALA D CB  1 
ATOM   12645 N N   . HIS D 1 223 ? -17.503 81.397  21.885 1.00 74.57  ? 231 HIS D N   1 
ATOM   12646 C CA  . HIS D 1 223 ? -16.518 81.244  20.825 1.00 83.84  ? 231 HIS D CA  1 
ATOM   12647 C C   . HIS D 1 223 ? -16.264 82.529  20.046 1.00 84.49  ? 231 HIS D C   1 
ATOM   12648 O O   . HIS D 1 223 ? -15.162 82.734  19.560 1.00 97.27  ? 231 HIS D O   1 
ATOM   12649 C CB  . HIS D 1 223 ? -16.855 80.083  19.891 1.00 100.28 ? 231 HIS D CB  1 
ATOM   12650 C CG  . HIS D 1 223 ? -15.933 78.936  20.090 1.00 100.03 ? 231 HIS D CG  1 
ATOM   12651 N ND1 . HIS D 1 223 ? -16.149 77.936  21.009 1.00 89.75  ? 231 HIS D ND1 1 
ATOM   12652 C CD2 . HIS D 1 223 ? -14.736 78.693  19.515 1.00 99.53  ? 231 HIS D CD2 1 
ATOM   12653 C CE1 . HIS D 1 223 ? -15.136 77.084  20.949 1.00 97.56  ? 231 HIS D CE1 1 
ATOM   12654 N NE2 . HIS D 1 223 ? -14.250 77.543  20.067 1.00 112.85 ? 231 HIS D NE2 1 
ATOM   12655 N N   . ILE D 1 224 ? -17.270 83.395  19.949 1.00 88.44  ? 232 ILE D N   1 
ATOM   12656 C CA  . ILE D 1 224 ? -17.206 84.540  19.049 1.00 79.94  ? 232 ILE D CA  1 
ATOM   12657 C C   . ILE D 1 224 ? -17.387 85.827  19.849 1.00 80.38  ? 232 ILE D C   1 
ATOM   12658 O O   . ILE D 1 224 ? -17.670 86.868  19.246 1.00 77.17  ? 232 ILE D O   1 
ATOM   12659 C CB  . ILE D 1 224 ? -18.284 84.400  17.952 1.00 82.36  ? 232 ILE D CB  1 
ATOM   12660 C CG1 . ILE D 1 224 ? -19.719 84.535  18.546 1.00 57.48  ? 232 ILE D CG1 1 
ATOM   12661 C CG2 . ILE D 1 224 ? -18.087 83.105  17.130 1.00 94.36  ? 232 ILE D CG2 1 
ATOM   12662 C CD1 . ILE D 1 224 ? -20.835 84.119  17.576 1.00 36.53  ? 232 ILE D CD1 1 
ATOM   12663 N N   . SER D 1 225 ? -17.188 85.758  21.180 1.00 71.16  ? 233 SER D N   1 
ATOM   12664 C CA  . SER D 1 225 ? -17.315 86.912  22.073 1.00 68.09  ? 233 SER D CA  1 
ATOM   12665 C C   . SER D 1 225 ? -16.620 88.119  21.483 1.00 71.00  ? 233 SER D C   1 
ATOM   12666 O O   . SER D 1 225 ? -17.204 89.198  21.312 1.00 67.70  ? 233 SER D O   1 
ATOM   12667 C CB  . SER D 1 225 ? -16.614 86.738  23.400 1.00 62.99  ? 233 SER D CB  1 
ATOM   12668 O OG  . SER D 1 225 ? -17.060 85.553  24.015 1.00 121.72 ? 233 SER D OG  1 
ATOM   12669 N N   . GLY D 1 226 ? -15.327 87.897  21.236 1.00 64.21  ? 234 GLY D N   1 
ATOM   12670 C CA  . GLY D 1 226 ? -14.479 88.942  20.696 1.00 66.66  ? 234 GLY D CA  1 
ATOM   12671 C C   . GLY D 1 226 ? -14.930 89.390  19.294 1.00 60.37  ? 234 GLY D C   1 
ATOM   12672 O O   . GLY D 1 226 ? -14.819 90.555  18.947 1.00 62.24  ? 234 GLY D O   1 
ATOM   12673 N N   . LEU D 1 227 ? -15.360 88.443  18.451 1.00 58.54  ? 235 LEU D N   1 
ATOM   12674 C CA  . LEU D 1 227 ? -15.742 88.772  17.092 1.00 69.19  ? 235 LEU D CA  1 
ATOM   12675 C C   . LEU D 1 227 ? -16.935 89.703  17.151 1.00 75.35  ? 235 LEU D C   1 
ATOM   12676 O O   . LEU D 1 227 ? -16.990 90.678  16.409 1.00 88.33  ? 235 LEU D O   1 
ATOM   12677 C CB  . LEU D 1 227 ? -16.076 87.510  16.302 1.00 83.91  ? 235 LEU D CB  1 
ATOM   12678 C CG  . LEU D 1 227 ? -14.903 86.585  15.969 1.00 82.78  ? 235 LEU D CG  1 
ATOM   12679 C CD1 . LEU D 1 227 ? -15.376 85.609  14.909 1.00 112.63 ? 235 LEU D CD1 1 
ATOM   12680 C CD2 . LEU D 1 227 ? -13.661 87.316  15.499 1.00 56.61  ? 235 LEU D CD2 1 
ATOM   12681 N N   . VAL D 1 228 ? -17.858 89.416  18.070 1.00 71.25  ? 236 VAL D N   1 
ATOM   12682 C CA  . VAL D 1 228 ? -19.087 90.184  18.137 1.00 81.29  ? 236 VAL D CA  1 
ATOM   12683 C C   . VAL D 1 228 ? -18.768 91.582  18.658 1.00 78.02  ? 236 VAL D C   1 
ATOM   12684 O O   . VAL D 1 228 ? -19.209 92.560  18.074 1.00 93.15  ? 236 VAL D O   1 
ATOM   12685 C CB  . VAL D 1 228 ? -20.136 89.446  18.984 1.00 84.75  ? 236 VAL D CB  1 
ATOM   12686 C CG1 . VAL D 1 228 ? -21.280 90.337  19.401 1.00 75.29  ? 236 VAL D CG1 1 
ATOM   12687 C CG2 . VAL D 1 228 ? -20.678 88.249  18.232 1.00 67.81  ? 236 VAL D CG2 1 
ATOM   12688 N N   . ALA D 1 229 ? -17.953 91.672  19.714 1.00 65.64  ? 237 ALA D N   1 
ATOM   12689 C CA  . ALA D 1 229 ? -17.484 92.942  20.269 1.00 78.08  ? 237 ALA D CA  1 
ATOM   12690 C C   . ALA D 1 229 ? -16.882 93.841  19.193 1.00 65.78  ? 237 ALA D C   1 
ATOM   12691 O O   . ALA D 1 229 ? -17.152 95.031  19.182 1.00 85.58  ? 237 ALA D O   1 
ATOM   12692 C CB  . ALA D 1 229 ? -16.500 92.712  21.415 1.00 69.26  ? 237 ALA D CB  1 
ATOM   12693 N N   . ALA D 1 230 ? -16.059 93.295  18.296 1.00 85.77  ? 238 ALA D N   1 
ATOM   12694 C CA  . ALA D 1 230 ? -15.425 94.096  17.252 1.00 117.70 ? 238 ALA D CA  1 
ATOM   12695 C C   . ALA D 1 230 ? -16.332 94.282  16.035 1.00 116.36 ? 238 ALA D C   1 
ATOM   12696 O O   . ALA D 1 230 ? -15.955 94.980  15.101 1.00 138.85 ? 238 ALA D O   1 
ATOM   12697 C CB  . ALA D 1 230 ? -14.088 93.521  16.852 1.00 133.44 ? 238 ALA D CB  1 
ATOM   12698 N N   . GLY D 1 231 ? -17.516 93.661  16.073 1.00 125.72 ? 239 GLY D N   1 
ATOM   12699 C CA  . GLY D 1 231 ? -18.553 93.818  15.066 1.00 115.62 ? 239 GLY D CA  1 
ATOM   12700 C C   . GLY D 1 231 ? -18.156 93.177  13.741 1.00 125.08 ? 239 GLY D C   1 
ATOM   12701 O O   . GLY D 1 231 ? -18.552 93.679  12.695 1.00 173.82 ? 239 GLY D O   1 
ATOM   12702 N N   . VAL D 1 232 ? -17.361 92.097  13.792 1.00 106.25 ? 240 VAL D N   1 
ATOM   12703 C CA  . VAL D 1 232 ? -16.824 91.419  12.621 1.00 91.41  ? 240 VAL D CA  1 
ATOM   12704 C C   . VAL D 1 232 ? -17.785 90.299  12.228 1.00 89.02  ? 240 VAL D C   1 
ATOM   12705 O O   . VAL D 1 232 ? -17.671 89.709  11.178 1.00 151.21 ? 240 VAL D O   1 
ATOM   12706 C CB  . VAL D 1 232 ? -15.403 90.934  12.994 1.00 88.10  ? 240 VAL D CB  1 
ATOM   12707 C CG1 . VAL D 1 232 ? -14.755 89.999  11.985 1.00 58.32  ? 240 VAL D CG1 1 
ATOM   12708 C CG2 . VAL D 1 232 ? -14.453 92.101  13.245 1.00 92.80  ? 240 VAL D CG2 1 
ATOM   12709 N N   . VAL D 1 233 ? -18.757 90.004  13.085 1.00 90.28  ? 241 VAL D N   1 
ATOM   12710 C CA  . VAL D 1 233 ? -19.772 88.988  12.881 1.00 90.85  ? 241 VAL D CA  1 
ATOM   12711 C C   . VAL D 1 233 ? -21.031 89.471  13.582 1.00 102.66 ? 241 VAL D C   1 
ATOM   12712 O O   . VAL D 1 233 ? -20.922 90.125  14.636 1.00 127.47 ? 241 VAL D O   1 
ATOM   12713 C CB  . VAL D 1 233 ? -19.225 87.784  13.664 1.00 107.69 ? 241 VAL D CB  1 
ATOM   12714 C CG1 . VAL D 1 233 ? -20.329 86.890  14.222 1.00 146.92 ? 241 VAL D CG1 1 
ATOM   12715 C CG2 . VAL D 1 233 ? -18.184 87.031  12.855 1.00 95.68  ? 241 VAL D CG2 1 
ATOM   12716 N N   . PRO D 1 234 ? -22.245 89.094  13.088 1.00 82.75  ? 242 PRO D N   1 
ATOM   12717 C CA  . PRO D 1 234 ? -23.518 89.623  13.589 1.00 91.34  ? 242 PRO D CA  1 
ATOM   12718 C C   . PRO D 1 234 ? -23.557 89.561  15.111 1.00 118.74 ? 242 PRO D C   1 
ATOM   12719 O O   . PRO D 1 234 ? -23.076 88.576  15.682 1.00 167.46 ? 242 PRO D O   1 
ATOM   12720 C CB  . PRO D 1 234 ? -24.588 88.668  12.973 1.00 90.13  ? 242 PRO D CB  1 
ATOM   12721 C CG  . PRO D 1 234 ? -23.807 87.405  12.594 1.00 77.86  ? 242 PRO D CG  1 
ATOM   12722 C CD  . PRO D 1 234 ? -22.502 88.069  12.060 1.00 85.64  ? 242 PRO D CD  1 
ATOM   12723 N N   . SER D 1 235 ? -24.166 90.572  15.751 1.00 94.58  ? 243 SER D N   1 
ATOM   12724 C CA  . SER D 1 235 ? -24.402 90.515  17.194 1.00 100.83 ? 243 SER D CA  1 
ATOM   12725 C C   . SER D 1 235 ? -25.644 89.714  17.620 1.00 109.32 ? 243 SER D C   1 
ATOM   12726 O O   . SER D 1 235 ? -26.740 89.854  17.062 1.00 132.63 ? 243 SER D O   1 
ATOM   12727 C CB  . SER D 1 235 ? -24.409 91.870  17.806 1.00 133.57 ? 243 SER D CB  1 
ATOM   12728 O OG  . SER D 1 235 ? -24.775 91.767  19.174 1.00 110.13 ? 243 SER D OG  1 
ATOM   12729 N N   . PRO D 1 236 ? -25.524 88.798  18.609 1.00 112.32 ? 244 PRO D N   1 
ATOM   12730 C CA  . PRO D 1 236 ? -26.705 88.055  19.051 1.00 110.52 ? 244 PRO D CA  1 
ATOM   12731 C C   . PRO D 1 236 ? -27.608 88.938  19.906 1.00 121.72 ? 244 PRO D C   1 
ATOM   12732 O O   . PRO D 1 236 ? -28.747 88.549  20.164 1.00 132.13 ? 244 PRO D O   1 
ATOM   12733 C CB  . PRO D 1 236 ? -26.055 86.942  19.860 1.00 89.13  ? 244 PRO D CB  1 
ATOM   12734 C CG  . PRO D 1 236 ? -24.849 87.643  20.487 1.00 100.68 ? 244 PRO D CG  1 
ATOM   12735 C CD  . PRO D 1 236 ? -24.274 88.417  19.309 1.00 94.07  ? 244 PRO D CD  1 
ATOM   12736 N N   . PHE D 1 237 ? -27.089 90.114  20.322 1.00 82.33  ? 245 PHE D N   1 
ATOM   12737 C CA  . PHE D 1 237 ? -27.808 90.956  21.269 1.00 88.11  ? 245 PHE D CA  1 
ATOM   12738 C C   . PHE D 1 237 ? -29.103 91.463  20.658 1.00 104.64 ? 245 PHE D C   1 
ATOM   12739 O O   . PHE D 1 237 ? -30.030 91.889  21.376 1.00 107.14 ? 245 PHE D O   1 
ATOM   12740 C CB  . PHE D 1 237 ? -26.984 92.116  21.819 1.00 65.67  ? 245 PHE D CB  1 
ATOM   12741 C CG  . PHE D 1 237 ? -26.010 91.593  22.842 1.00 71.30  ? 245 PHE D CG  1 
ATOM   12742 C CD1 . PHE D 1 237 ? -26.396 91.290  24.160 1.00 83.26  ? 245 PHE D CD1 1 
ATOM   12743 C CD2 . PHE D 1 237 ? -24.704 91.378  22.448 1.00 86.12  ? 245 PHE D CD2 1 
ATOM   12744 C CE1 . PHE D 1 237 ? -25.461 90.780  25.057 1.00 91.26  ? 245 PHE D CE1 1 
ATOM   12745 C CE2 . PHE D 1 237 ? -23.783 90.858  23.344 1.00 117.64 ? 245 PHE D CE2 1 
ATOM   12746 C CZ  . PHE D 1 237 ? -24.149 90.570  24.634 1.00 111.15 ? 245 PHE D CZ  1 
ATOM   12747 N N   . GLU D 1 238 ? -29.143 91.397  19.320 1.00 88.67  ? 246 GLU D N   1 
ATOM   12748 C CA  . GLU D 1 238 ? -30.216 92.087  18.649 1.00 87.42  ? 246 GLU D CA  1 
ATOM   12749 C C   . GLU D 1 238 ? -31.484 91.238  18.674 1.00 91.28  ? 246 GLU D C   1 
ATOM   12750 O O   . GLU D 1 238 ? -32.560 91.783  18.521 1.00 121.37 ? 246 GLU D O   1 
ATOM   12751 C CB  . GLU D 1 238 ? -29.676 92.365  17.262 1.00 104.76 ? 246 GLU D CB  1 
ATOM   12752 C CG  . GLU D 1 238 ? -30.597 93.252  16.437 1.00 137.91 ? 246 GLU D CG  1 
ATOM   12753 C CD  . GLU D 1 238 ? -30.284 93.191  14.957 1.00 152.35 ? 246 GLU D CD  1 
ATOM   12754 O OE1 . GLU D 1 238 ? -31.112 93.705  14.185 1.00 162.81 ? 246 GLU D OE1 1 
ATOM   12755 O OE2 . GLU D 1 238 ? -29.248 92.620  14.568 1.00 156.69 ? 246 GLU D OE2 1 
ATOM   12756 N N   . HIS D 1 239 ? -31.377 89.919  18.893 1.00 103.07 ? 247 HIS D N   1 
ATOM   12757 C CA  . HIS D 1 239 ? -32.540 89.032  18.855 1.00 103.92 ? 247 HIS D CA  1 
ATOM   12758 C C   . HIS D 1 239 ? -32.697 88.195  20.129 1.00 90.41  ? 247 HIS D C   1 
ATOM   12759 O O   . HIS D 1 239 ? -33.793 87.768  20.414 1.00 68.36  ? 247 HIS D O   1 
ATOM   12760 C CB  . HIS D 1 239 ? -32.471 88.039  17.698 1.00 100.64 ? 247 HIS D CB  1 
ATOM   12761 C CG  . HIS D 1 239 ? -31.963 88.695  16.467 1.00 110.84 ? 247 HIS D CG  1 
ATOM   12762 N ND1 . HIS D 1 239 ? -32.854 89.071  15.489 1.00 130.63 ? 247 HIS D ND1 1 
ATOM   12763 C CD2 . HIS D 1 239 ? -30.744 89.073  16.051 1.00 96.90  ? 247 HIS D CD2 1 
ATOM   12764 C CE1 . HIS D 1 239 ? -32.192 89.635  14.495 1.00 140.15 ? 247 HIS D CE1 1 
ATOM   12765 N NE2 . HIS D 1 239 ? -30.916 89.657  14.822 1.00 156.64 ? 247 HIS D NE2 1 
ATOM   12766 N N   . CYS D 1 240 ? -31.623 87.948  20.895 1.00 76.74  ? 248 CYS D N   1 
ATOM   12767 C CA  . CYS D 1 240 ? -31.670 87.050  22.046 1.00 83.22  ? 248 CYS D CA  1 
ATOM   12768 C C   . CYS D 1 240 ? -32.190 87.704  23.333 1.00 87.47  ? 248 CYS D C   1 
ATOM   12769 O O   . CYS D 1 240 ? -32.037 88.912  23.526 1.00 135.58 ? 248 CYS D O   1 
ATOM   12770 C CB  . CYS D 1 240 ? -30.294 86.450  22.256 1.00 88.82  ? 248 CYS D CB  1 
ATOM   12771 S SG  . CYS D 1 240 ? -29.792 85.497  20.808 1.00 91.18  ? 248 CYS D SG  1 
ATOM   12772 N N   . HIS D 1 241 ? -32.786 86.896  24.224 1.00 77.09  ? 249 HIS D N   1 
ATOM   12773 C CA  . HIS D 1 241 ? -33.265 87.383  25.514 1.00 86.31  ? 249 HIS D CA  1 
ATOM   12774 C C   . HIS D 1 241 ? -32.104 87.487  26.487 1.00 80.95  ? 249 HIS D C   1 
ATOM   12775 O O   . HIS D 1 241 ? -32.071 88.365  27.343 1.00 75.05  ? 249 HIS D O   1 
ATOM   12776 C CB  . HIS D 1 241 ? -34.267 86.403  26.141 1.00 76.97  ? 249 HIS D CB  1 
ATOM   12777 C CG  . HIS D 1 241 ? -35.530 86.377  25.352 1.00 101.12 ? 249 HIS D CG  1 
ATOM   12778 N ND1 . HIS D 1 241 ? -35.826 85.387  24.445 1.00 92.46  ? 249 HIS D ND1 1 
ATOM   12779 C CD2 . HIS D 1 241 ? -36.573 87.209  25.335 1.00 109.73 ? 249 HIS D CD2 1 
ATOM   12780 C CE1 . HIS D 1 241 ? -37.035 85.613  23.944 1.00 116.42 ? 249 HIS D CE1 1 
ATOM   12781 N NE2 . HIS D 1 241 ? -37.499 86.732  24.440 1.00 108.01 ? 249 HIS D NE2 1 
ATOM   12782 N N   . VAL D 1 242 ? -31.192 86.532  26.341 1.00 70.19  ? 250 VAL D N   1 
ATOM   12783 C CA  . VAL D 1 242 ? -30.051 86.388  27.215 1.00 57.84  ? 250 VAL D CA  1 
ATOM   12784 C C   . VAL D 1 242 ? -28.878 85.950  26.351 1.00 69.70  ? 250 VAL D C   1 
ATOM   12785 O O   . VAL D 1 242 ? -29.034 85.156  25.398 1.00 56.93  ? 250 VAL D O   1 
ATOM   12786 C CB  . VAL D 1 242 ? -30.370 85.315  28.265 1.00 55.59  ? 250 VAL D CB  1 
ATOM   12787 C CG1 . VAL D 1 242 ? -29.129 84.799  28.981 1.00 50.92  ? 250 VAL D CG1 1 
ATOM   12788 C CG2 . VAL D 1 242 ? -31.377 85.847  29.255 1.00 55.84  ? 250 VAL D CG2 1 
ATOM   12789 N N   . VAL D 1 243 ? -27.692 86.461  26.736 1.00 56.85  ? 251 VAL D N   1 
ATOM   12790 C CA  . VAL D 1 243 ? -26.465 86.039  26.076 1.00 62.54  ? 251 VAL D CA  1 
ATOM   12791 C C   . VAL D 1 243 ? -25.437 85.681  27.141 1.00 87.32  ? 251 VAL D C   1 
ATOM   12792 O O   . VAL D 1 243 ? -25.100 86.545  27.972 1.00 82.15  ? 251 VAL D O   1 
ATOM   12793 C CB  . VAL D 1 243 ? -25.949 87.167  25.172 1.00 55.52  ? 251 VAL D CB  1 
ATOM   12794 C CG1 . VAL D 1 243 ? -24.649 86.767  24.528 1.00 58.03  ? 251 VAL D CG1 1 
ATOM   12795 C CG2 . VAL D 1 243 ? -26.940 87.551  24.094 1.00 49.45  ? 251 VAL D CG2 1 
ATOM   12796 N N   . THR D 1 244 ? -24.932 84.430  27.073 1.00 84.17  ? 252 THR D N   1 
ATOM   12797 C CA  . THR D 1 244 ? -23.885 84.009  27.997 1.00 88.25  ? 252 THR D CA  1 
ATOM   12798 C C   . THR D 1 244 ? -22.570 84.002  27.237 1.00 78.26  ? 252 THR D C   1 
ATOM   12799 O O   . THR D 1 244 ? -22.565 83.855  26.015 1.00 98.45  ? 252 THR D O   1 
ATOM   12800 C CB  . THR D 1 244 ? -24.156 82.639  28.625 1.00 94.89  ? 252 THR D CB  1 
ATOM   12801 O OG1 . THR D 1 244 ? -24.277 81.701  27.565 1.00 63.64  ? 252 THR D OG1 1 
ATOM   12802 C CG2 . THR D 1 244 ? -25.434 82.570  29.442 1.00 100.82 ? 252 THR D CG2 1 
ATOM   12803 N N   . THR D 1 245 ? -21.469 84.159  27.970 1.00 72.46  ? 253 THR D N   1 
ATOM   12804 C CA  . THR D 1 245 ? -20.176 84.066  27.313 1.00 93.76  ? 253 THR D CA  1 
ATOM   12805 C C   . THR D 1 245 ? -19.066 83.730  28.303 1.00 84.16  ? 253 THR D C   1 
ATOM   12806 O O   . THR D 1 245 ? -19.134 83.999  29.489 1.00 77.32  ? 253 THR D O   1 
ATOM   12807 C CB  . THR D 1 245 ? -19.868 85.402  26.656 1.00 86.57  ? 253 THR D CB  1 
ATOM   12808 O OG1 . THR D 1 245 ? -18.732 85.139  25.841 1.00 82.03  ? 253 THR D OG1 1 
ATOM   12809 C CG2 . THR D 1 245 ? -19.500 86.417  27.715 1.00 107.62 ? 253 THR D CG2 1 
ATOM   12810 N N   . THR D 1 246 ? -18.000 83.187  27.745 1.00 73.04  ? 254 THR D N   1 
ATOM   12811 C CA  . THR D 1 246 ? -16.730 83.062  28.413 1.00 67.66  ? 254 THR D CA  1 
ATOM   12812 C C   . THR D 1 246 ? -15.931 84.368  28.251 1.00 77.31  ? 254 THR D C   1 
ATOM   12813 O O   . THR D 1 246 ? -15.920 84.993  27.162 1.00 63.14  ? 254 THR D O   1 
ATOM   12814 C CB  . THR D 1 246 ? -16.107 81.987  27.534 1.00 81.62  ? 254 THR D CB  1 
ATOM   12815 O OG1 . THR D 1 246 ? -15.272 81.272  28.442 1.00 69.75  ? 254 THR D OG1 1 
ATOM   12816 C CG2 . THR D 1 246 ? -15.627 82.565  26.183 1.00 58.06  ? 254 THR D CG2 1 
ATOM   12817 N N   . THR D 1 247 ? -15.124 84.680  29.277 1.00 63.64  ? 255 THR D N   1 
ATOM   12818 C CA  . THR D 1 247 ? -14.306 85.881  29.242 1.00 63.79  ? 255 THR D CA  1 
ATOM   12819 C C   . THR D 1 247 ? -12.944 85.570  28.623 1.00 61.56  ? 255 THR D C   1 
ATOM   12820 O O   . THR D 1 247 ? -12.237 86.514  28.295 1.00 51.97  ? 255 THR D O   1 
ATOM   12821 C CB  . THR D 1 247 ? -14.164 86.539  30.623 1.00 77.16  ? 255 THR D CB  1 
ATOM   12822 O OG1 . THR D 1 247 ? -13.611 85.591  31.532 1.00 93.67  ? 255 THR D OG1 1 
ATOM   12823 C CG2 . THR D 1 247 ? -15.489 87.059  31.160 1.00 87.66  ? 255 THR D CG2 1 
ATOM   12824 N N   . HIS D 1 248 ? -12.573 84.280  28.495 1.00 47.11  ? 256 HIS D N   1 
ATOM   12825 C CA  . HIS D 1 248 ? -11.441 83.915  27.650 1.00 62.01  ? 256 HIS D CA  1 
ATOM   12826 C C   . HIS D 1 248 ? -11.829 83.663  26.170 1.00 65.02  ? 256 HIS D C   1 
ATOM   12827 O O   . HIS D 1 248 ? -12.766 84.302  25.602 1.00 41.21  ? 256 HIS D O   1 
ATOM   12828 C CB  . HIS D 1 248 ? -10.742 82.725  28.283 1.00 72.35  ? 256 HIS D CB  1 
ATOM   12829 C CG  . HIS D 1 248 ? -11.638 81.598  28.701 1.00 83.36  ? 256 HIS D CG  1 
ATOM   12830 N ND1 . HIS D 1 248 ? -12.378 81.580  29.869 1.00 66.74  ? 256 HIS D ND1 1 
ATOM   12831 C CD2 . HIS D 1 248 ? -11.835 80.408  28.100 1.00 102.28 ? 256 HIS D CD2 1 
ATOM   12832 C CE1 . HIS D 1 248 ? -13.010 80.407  29.969 1.00 95.02  ? 256 HIS D CE1 1 
ATOM   12833 N NE2 . HIS D 1 248 ? -12.697 79.681  28.908 1.00 110.19 ? 256 HIS D NE2 1 
ATOM   12834 N N   . LYS D 1 249 ? -11.112 82.700  25.555 1.00 49.53  ? 257 LYS D N   1 
ATOM   12835 C CA  . LYS D 1 249 ? -11.285 82.494  24.120 1.00 88.46  ? 257 LYS D CA  1 
ATOM   12836 C C   . LYS D 1 249 ? -11.074 83.801  23.341 1.00 90.77  ? 257 LYS D C   1 
ATOM   12837 O O   . LYS D 1 249 ? -10.101 84.514  23.593 1.00 94.53  ? 257 LYS D O   1 
ATOM   12838 C CB  . LYS D 1 249 ? -12.621 81.799  23.848 1.00 79.35  ? 257 LYS D CB  1 
ATOM   12839 C CG  . LYS D 1 249 ? -12.724 80.514  24.660 1.00 66.55  ? 257 LYS D CG  1 
ATOM   12840 C CD  . LYS D 1 249 ? -14.040 79.759  24.469 1.00 72.38  ? 257 LYS D CD  1 
ATOM   12841 C CE  . LYS D 1 249 ? -13.878 78.463  25.230 1.00 67.71  ? 257 LYS D CE  1 
ATOM   12842 N NZ  . LYS D 1 249 ? -14.821 77.391  24.910 1.00 57.19  ? 257 LYS D NZ  1 
ATOM   12843 N N   . THR D 1 250 ? -11.977 84.116  22.396 1.00 71.54  ? 258 THR D N   1 
ATOM   12844 C CA  . THR D 1 250 ? -11.815 85.316  21.578 1.00 93.73  ? 258 THR D CA  1 
ATOM   12845 C C   . THR D 1 250 ? -11.898 86.641  22.360 1.00 84.84  ? 258 THR D C   1 
ATOM   12846 O O   . THR D 1 250 ? -11.612 87.712  21.822 1.00 74.99  ? 258 THR D O   1 
ATOM   12847 C CB  . THR D 1 250 ? -12.764 85.326  20.380 1.00 101.08 ? 258 THR D CB  1 
ATOM   12848 O OG1 . THR D 1 250 ? -14.101 85.103  20.846 1.00 64.04  ? 258 THR D OG1 1 
ATOM   12849 C CG2 . THR D 1 250 ? -12.327 84.350  19.301 1.00 139.23 ? 258 THR D CG2 1 
ATOM   12850 N N   . LEU D 1 251 ? -12.328 86.599  23.620 1.00 82.61  ? 259 LEU D N   1 
ATOM   12851 C CA  . LEU D 1 251 ? -12.426 87.825  24.391 1.00 86.63  ? 259 LEU D CA  1 
ATOM   12852 C C   . LEU D 1 251 ? -11.101 88.085  25.099 1.00 77.71  ? 259 LEU D C   1 
ATOM   12853 O O   . LEU D 1 251 ? -10.930 89.171  25.686 1.00 77.27  ? 259 LEU D O   1 
ATOM   12854 C CB  . LEU D 1 251 ? -13.590 87.763  25.380 1.00 75.74  ? 259 LEU D CB  1 
ATOM   12855 C CG  . LEU D 1 251 ? -14.130 89.099  25.890 1.00 61.37  ? 259 LEU D CG  1 
ATOM   12856 C CD1 . LEU D 1 251 ? -14.629 89.879  24.725 1.00 72.14  ? 259 LEU D CD1 1 
ATOM   12857 C CD2 . LEU D 1 251 ? -15.306 88.814  26.763 1.00 78.95  ? 259 LEU D CD2 1 
ATOM   12858 N N   . ARG D 1 252 ? -10.208 87.070  25.030 1.00 63.83  ? 260 ARG D N   1 
ATOM   12859 C CA  . ARG D 1 252 ? -8.792  87.177  25.385 1.00 88.99  ? 260 ARG D CA  1 
ATOM   12860 C C   . ARG D 1 252 ? -8.576  87.634  26.832 1.00 93.82  ? 260 ARG D C   1 
ATOM   12861 O O   . ARG D 1 252 ? -7.582  88.324  27.159 1.00 121.66 ? 260 ARG D O   1 
ATOM   12862 C CB  . ARG D 1 252 ? -8.035  88.171  24.488 1.00 101.53 ? 260 ARG D CB  1 
ATOM   12863 C CG  . ARG D 1 252 ? -7.443  87.693  23.167 1.00 118.03 ? 260 ARG D CG  1 
ATOM   12864 C CD  . ARG D 1 252 ? -5.987  88.114  23.020 1.00 108.58 ? 260 ARG D CD  1 
ATOM   12865 N NE  . ARG D 1 252 ? -5.970  89.580  23.016 1.00 105.14 ? 260 ARG D NE  1 
ATOM   12866 C CZ  . ARG D 1 252 ? -5.783  90.313  21.934 1.00 103.16 ? 260 ARG D CZ  1 
ATOM   12867 N NH1 . ARG D 1 252 ? -5.388  89.748  20.799 1.00 64.53  ? 260 ARG D NH1 1 
ATOM   12868 N NH2 . ARG D 1 252 ? -6.074  91.601  21.999 1.00 138.81 ? 260 ARG D NH2 1 
ATOM   12869 N N   . GLY D 1 253 ? -9.513  87.253  27.701 1.00 54.44  ? 261 GLY D N   1 
ATOM   12870 C CA  . GLY D 1 253 ? -9.364  87.594  29.105 1.00 52.86  ? 261 GLY D CA  1 
ATOM   12871 C C   . GLY D 1 253 ? -9.002  86.339  29.875 1.00 70.60  ? 261 GLY D C   1 
ATOM   12872 O O   . GLY D 1 253 ? -8.675  85.313  29.225 1.00 89.67  ? 261 GLY D O   1 
ATOM   12873 N N   . CYS D 1 254 ? -9.048  86.449  31.224 1.00 51.89  ? 262 CYS D N   1 
ATOM   12874 C CA  . CYS D 1 254 ? -8.795  85.269  32.041 1.00 52.54  ? 262 CYS D CA  1 
ATOM   12875 C C   . CYS D 1 254 ? -10.021 84.362  32.000 1.00 69.06  ? 262 CYS D C   1 
ATOM   12876 O O   . CYS D 1 254 ? -11.081 84.760  31.492 1.00 78.42  ? 262 CYS D O   1 
ATOM   12877 C CB  . CYS D 1 254 ? -8.430  85.645  33.463 1.00 46.04  ? 262 CYS D CB  1 
ATOM   12878 S SG  . CYS D 1 254 ? -9.682  86.670  34.261 1.00 60.81  ? 262 CYS D SG  1 
ATOM   12879 N N   . ARG D 1 255 ? -9.871  83.145  32.532 1.00 73.59  ? 263 ARG D N   1 
ATOM   12880 C CA  . ARG D 1 255 ? -11.007 82.241  32.561 1.00 82.83  ? 263 ARG D CA  1 
ATOM   12881 C C   . ARG D 1 255 ? -11.999 82.706  33.624 1.00 76.57  ? 263 ARG D C   1 
ATOM   12882 O O   . ARG D 1 255 ? -11.624 82.772  34.802 1.00 66.26  ? 263 ARG D O   1 
ATOM   12883 C CB  . ARG D 1 255 ? -10.522 80.804  32.772 1.00 89.43  ? 263 ARG D CB  1 
ATOM   12884 C CG  . ARG D 1 255 ? -9.684  80.241  31.639 1.00 81.12  ? 263 ARG D CG  1 
ATOM   12885 C CD  . ARG D 1 255 ? -8.893  79.033  32.149 1.00 130.71 ? 263 ARG D CD  1 
ATOM   12886 N NE  . ARG D 1 255 ? -8.331  78.229  31.063 1.00 125.17 ? 263 ARG D NE  1 
ATOM   12887 C CZ  . ARG D 1 255 ? -9.080  77.519  30.235 1.00 102.31 ? 263 ARG D CZ  1 
ATOM   12888 N NH1 . ARG D 1 255 ? -10.398 77.418  30.420 1.00 97.56  ? 263 ARG D NH1 1 
ATOM   12889 N NH2 . ARG D 1 255 ? -8.472  76.886  29.267 1.00 63.35  ? 263 ARG D NH2 1 
ATOM   12890 N N   . ALA D 1 256 ? -13.209 83.075  33.141 1.00 66.55  ? 264 ALA D N   1 
ATOM   12891 C CA  . ALA D 1 256 ? -14.417 83.431  33.879 1.00 76.08  ? 264 ALA D CA  1 
ATOM   12892 C C   . ALA D 1 256 ? -15.584 83.536  32.888 1.00 81.13  ? 264 ALA D C   1 
ATOM   12893 O O   . ALA D 1 256 ? -15.401 83.393  31.694 1.00 86.46  ? 264 ALA D O   1 
ATOM   12894 C CB  . ALA D 1 256 ? -14.229 84.711  34.692 1.00 76.66  ? 264 ALA D CB  1 
ATOM   12895 N N   . GLY D 1 257 ? -16.796 83.837  33.346 1.00 99.01  ? 265 GLY D N   1 
ATOM   12896 C CA  . GLY D 1 257 ? -17.937 83.956  32.442 1.00 101.73 ? 265 GLY D CA  1 
ATOM   12897 C C   . GLY D 1 257 ? -18.858 85.120  32.826 1.00 110.56 ? 265 GLY D C   1 
ATOM   12898 O O   . GLY D 1 257 ? -18.717 85.719  33.902 1.00 106.47 ? 265 GLY D O   1 
ATOM   12899 N N   . MET D 1 258 ? -19.815 85.419  31.935 1.00 82.44  ? 266 MET D N   1 
ATOM   12900 C CA  . MET D 1 258 ? -20.701 86.551  32.118 1.00 73.85  ? 266 MET D CA  1 
ATOM   12901 C C   . MET D 1 258 ? -22.060 86.198  31.549 1.00 70.86  ? 266 MET D C   1 
ATOM   12902 O O   . MET D 1 258 ? -22.139 85.460  30.575 1.00 78.92  ? 266 MET D O   1 
ATOM   12903 C CB  . MET D 1 258 ? -20.193 87.772  31.349 1.00 78.22  ? 266 MET D CB  1 
ATOM   12904 C CG  . MET D 1 258 ? -18.964 88.388  31.975 1.00 81.02  ? 266 MET D CG  1 
ATOM   12905 S SD  . MET D 1 258 ? -18.545 89.877  31.072 1.00 93.79  ? 266 MET D SD  1 
ATOM   12906 C CE  . MET D 1 258 ? -18.239 89.529  29.340 1.00 56.91  ? 266 MET D CE  1 
ATOM   12907 N N   . ILE D 1 259 ? -23.117 86.784  32.133 1.00 64.16  ? 267 ILE D N   1 
ATOM   12908 C CA  . ILE D 1 259 ? -24.477 86.559  31.658 1.00 69.97  ? 267 ILE D CA  1 
ATOM   12909 C C   . ILE D 1 259 ? -25.077 87.929  31.374 1.00 88.03  ? 267 ILE D C   1 
ATOM   12910 O O   . ILE D 1 259 ? -25.283 88.696  32.321 1.00 83.66  ? 267 ILE D O   1 
ATOM   12911 C CB  . ILE D 1 259 ? -25.327 85.794  32.700 1.00 64.18  ? 267 ILE D CB  1 
ATOM   12912 C CG1 . ILE D 1 259 ? -24.714 84.432  33.070 1.00 67.57  ? 267 ILE D CG1 1 
ATOM   12913 C CG2 . ILE D 1 259 ? -26.791 85.681  32.268 1.00 48.08  ? 267 ILE D CG2 1 
ATOM   12914 C CD1 . ILE D 1 259 ? -25.340 83.766  34.283 1.00 60.81  ? 267 ILE D CD1 1 
ATOM   12915 N N   . PHE D 1 260 ? -25.360 88.205  30.080 1.00 77.71  ? 268 PHE D N   1 
ATOM   12916 C CA  . PHE D 1 260 ? -26.138 89.386  29.710 1.00 82.75  ? 268 PHE D CA  1 
ATOM   12917 C C   . PHE D 1 260 ? -27.628 89.031  29.637 1.00 92.24  ? 268 PHE D C   1 
ATOM   12918 O O   . PHE D 1 260 ? -27.970 87.971  29.110 1.00 58.19  ? 268 PHE D O   1 
ATOM   12919 C CB  . PHE D 1 260 ? -25.671 89.913  28.360 1.00 70.10  ? 268 PHE D CB  1 
ATOM   12920 C CG  . PHE D 1 260 ? -24.213 90.342  28.338 1.00 78.69  ? 268 PHE D CG  1 
ATOM   12921 C CD1 . PHE D 1 260 ? -23.222 89.414  28.059 1.00 82.08  ? 268 PHE D CD1 1 
ATOM   12922 C CD2 . PHE D 1 260 ? -23.834 91.674  28.571 1.00 100.75 ? 268 PHE D CD2 1 
ATOM   12923 C CE1 . PHE D 1 260 ? -21.889 89.813  28.047 1.00 108.28 ? 268 PHE D CE1 1 
ATOM   12924 C CE2 . PHE D 1 260 ? -22.492 92.064  28.535 1.00 99.75  ? 268 PHE D CE2 1 
ATOM   12925 C CZ  . PHE D 1 260 ? -21.516 91.135  28.263 1.00 100.86 ? 268 PHE D CZ  1 
ATOM   12926 N N   . TYR D 1 261 ? -28.511 89.928  30.124 1.00 89.39  ? 269 TYR D N   1 
ATOM   12927 C CA  . TYR D 1 261 ? -29.942 89.650  30.159 1.00 82.54  ? 269 TYR D CA  1 
ATOM   12928 C C   . TYR D 1 261 ? -30.748 90.918  29.888 1.00 82.90  ? 269 TYR D C   1 
ATOM   12929 O O   . TYR D 1 261 ? -30.301 92.031  30.218 1.00 63.86  ? 269 TYR D O   1 
ATOM   12930 C CB  . TYR D 1 261 ? -30.359 89.105  31.525 1.00 80.76  ? 269 TYR D CB  1 
ATOM   12931 C CG  . TYR D 1 261 ? -29.746 89.883  32.681 1.00 100.51 ? 269 TYR D CG  1 
ATOM   12932 C CD1 . TYR D 1 261 ? -30.344 91.035  33.186 1.00 107.10 ? 269 TYR D CD1 1 
ATOM   12933 C CD2 . TYR D 1 261 ? -28.569 89.457  33.281 1.00 116.00 ? 269 TYR D CD2 1 
ATOM   12934 C CE1 . TYR D 1 261 ? -29.791 91.747  34.242 1.00 101.49 ? 269 TYR D CE1 1 
ATOM   12935 C CE2 . TYR D 1 261 ? -28.017 90.156  34.346 1.00 123.23 ? 269 TYR D CE2 1 
ATOM   12936 C CZ  . TYR D 1 261 ? -28.623 91.303  34.825 1.00 111.54 ? 269 TYR D CZ  1 
ATOM   12937 O OH  . TYR D 1 261 ? -28.052 91.973  35.857 1.00 145.02 ? 269 TYR D OH  1 
ATOM   12938 N N   . ARG D 1 262 ? -31.947 90.719  29.302 1.00 85.02  ? 270 ARG D N   1 
ATOM   12939 C CA  . ARG D 1 262 ? -32.811 91.822  28.892 1.00 87.22  ? 270 ARG D CA  1 
ATOM   12940 C C   . ARG D 1 262 ? -33.474 92.434  30.131 1.00 91.59  ? 270 ARG D C   1 
ATOM   12941 O O   . ARG D 1 262 ? -33.869 91.703  31.041 1.00 98.57  ? 270 ARG D O   1 
ATOM   12942 C CB  . ARG D 1 262 ? -33.728 91.577  27.674 1.00 83.11  ? 270 ARG D CB  1 
ATOM   12943 C CG  . ARG D 1 262 ? -34.074 92.959  27.103 1.00 92.29  ? 270 ARG D CG  1 
ATOM   12944 C CD  . ARG D 1 262 ? -34.708 93.527  25.818 1.00 60.27  ? 270 ARG D CD  1 
ATOM   12945 N NE  . ARG D 1 262 ? -33.768 93.364  24.692 1.00 91.41  ? 270 ARG D NE  1 
ATOM   12946 C CZ  . ARG D 1 262 ? -34.042 92.933  23.413 1.00 126.42 ? 270 ARG D CZ  1 
ATOM   12947 N NH1 . ARG D 1 262 ? -35.243 92.415  23.138 1.00 160.88 ? 270 ARG D NH1 1 
ATOM   12948 N NH2 . ARG D 1 262 ? -33.131 92.981  22.422 1.00 71.83  ? 270 ARG D NH2 1 
ATOM   12949 N N   . LYS D 1 263 ? -33.508 93.785  30.178 1.00 89.09  ? 271 LYS D N   1 
ATOM   12950 C CA  . LYS D 1 263 ? -34.283 94.563  31.134 1.00 94.17  ? 271 LYS D CA  1 
ATOM   12951 C C   . LYS D 1 263 ? -35.317 95.388  30.371 1.00 82.94  ? 271 LYS D C   1 
ATOM   12952 O O   . LYS D 1 263 ? -35.071 95.747  29.228 1.00 75.30  ? 271 LYS D O   1 
ATOM   12953 C CB  . LYS D 1 263 ? -33.398 95.651  31.764 1.00 90.51  ? 271 LYS D CB  1 
ATOM   12954 C CG  . LYS D 1 263 ? -32.167 95.231  32.563 1.00 83.41  ? 271 LYS D CG  1 
ATOM   12955 C CD  . LYS D 1 263 ? -31.880 95.679  34.017 1.00 61.43  ? 271 LYS D CD  1 
ATOM   12956 C CE  . LYS D 1 263 ? -31.134 96.977  34.307 1.00 60.29  ? 271 LYS D CE  1 
ATOM   12957 N NZ  . LYS D 1 263 ? -29.964 97.103  33.444 1.00 67.95  ? 271 LYS D NZ  1 
ATOM   12958 N N   . GLY D 1 264 ? -36.481 95.669  30.977 1.00 89.13  ? 272 GLY D N   1 
ATOM   12959 C CA  . GLY D 1 264 ? -37.452 96.553  30.344 1.00 98.19  ? 272 GLY D CA  1 
ATOM   12960 C C   . GLY D 1 264 ? -38.800 95.871  30.138 1.00 113.49 ? 272 GLY D C   1 
ATOM   12961 O O   . GLY D 1 264 ? -39.175 94.952  30.867 1.00 151.46 ? 272 GLY D O   1 
ATOM   12962 N N   . VAL D 1 265 ? -39.606 96.383  29.199 1.00 111.24 ? 273 VAL D N   1 
ATOM   12963 C CA  . VAL D 1 265 ? -40.927 95.794  28.972 1.00 108.82 ? 273 VAL D CA  1 
ATOM   12964 C C   . VAL D 1 265 ? -40.785 94.555  28.092 1.00 97.04  ? 273 VAL D C   1 
ATOM   12965 O O   . VAL D 1 265 ? -40.209 94.639  27.015 1.00 76.06  ? 273 VAL D O   1 
ATOM   12966 C CB  . VAL D 1 265 ? -41.811 96.852  28.291 1.00 114.69 ? 273 VAL D CB  1 
ATOM   12967 C CG1 . VAL D 1 265 ? -43.230 96.358  28.040 1.00 104.40 ? 273 VAL D CG1 1 
ATOM   12968 C CG2 . VAL D 1 265 ? -41.795 98.171  29.054 1.00 113.96 ? 273 VAL D CG2 1 
ATOM   12969 N N   . LYS D 1 266 ? -41.287 93.417  28.560 1.00 113.94 ? 274 LYS D N   1 
ATOM   12970 C CA  . LYS D 1 266 ? -41.246 92.195  27.722 1.00 111.38 ? 274 LYS D CA  1 
ATOM   12971 C C   . LYS D 1 266 ? -42.415 92.269  26.754 1.00 110.93 ? 274 LYS D C   1 
ATOM   12972 O O   . LYS D 1 266 ? -42.208 92.051  25.552 1.00 134.79 ? 274 LYS D O   1 
ATOM   12973 C CB  . LYS D 1 266 ? -41.365 90.930  28.573 1.00 109.87 ? 274 LYS D CB  1 
ATOM   12974 C CG  . LYS D 1 266 ? -41.212 89.621  27.812 1.00 69.53  ? 274 LYS D CG  1 
ATOM   12975 C CD  . LYS D 1 266 ? -41.209 88.395  28.699 1.00 63.29  ? 274 LYS D CD  1 
ATOM   12976 C CE  . LYS D 1 266 ? -42.564 88.084  29.295 1.00 84.48  ? 274 LYS D CE  1 
ATOM   12977 N NZ  . LYS D 1 266 ? -42.588 86.748  29.936 1.00 68.99  ? 274 LYS D NZ  1 
ATOM   12978 N N   . SER D 1 267 ? -43.593 92.593  27.276 1.00 106.79 ? 275 SER D N   1 
ATOM   12979 C CA  . SER D 1 267 ? -44.792 92.699  26.415 1.00 134.74 ? 275 SER D CA  1 
ATOM   12980 C C   . SER D 1 267 ? -45.866 93.502  27.141 1.00 148.99 ? 275 SER D C   1 
ATOM   12981 O O   . SER D 1 267 ? -45.813 93.563  28.378 1.00 139.93 ? 275 SER D O   1 
ATOM   12982 C CB  . SER D 1 267 ? -45.296 91.340  26.062 1.00 119.41 ? 275 SER D CB  1 
ATOM   12983 O OG  . SER D 1 267 ? -45.724 90.649  27.225 1.00 160.94 ? 275 SER D OG  1 
ATOM   12984 N N   . VAL D 1 268 ? -46.794 94.098  26.394 1.00 170.89 ? 276 VAL D N   1 
ATOM   12985 C CA  . VAL D 1 268 ? -47.925 94.836  27.024 1.00 166.00 ? 276 VAL D CA  1 
ATOM   12986 C C   . VAL D 1 268 ? -49.154 93.932  26.966 1.00 190.81 ? 276 VAL D C   1 
ATOM   12987 O O   . VAL D 1 268 ? -49.404 93.356  25.894 1.00 213.45 ? 276 VAL D O   1 
ATOM   12988 C CB  . VAL D 1 268 ? -48.186 96.178  26.318 1.00 128.98 ? 276 VAL D CB  1 
ATOM   12989 C CG1 . VAL D 1 268 ? -49.593 96.692  26.582 1.00 118.89 ? 276 VAL D CG1 1 
ATOM   12990 C CG2 . VAL D 1 268 ? -47.150 97.223  26.696 1.00 107.37 ? 276 VAL D CG2 1 
ATOM   12991 N N   . ASP D 1 269 ? -49.873 93.804  28.081 1.00 189.54 ? 277 ASP D N   1 
ATOM   12992 C CA  . ASP D 1 269 ? -51.069 92.924  28.132 1.00 220.21 ? 277 ASP D CA  1 
ATOM   12993 C C   . ASP D 1 269 ? -52.306 93.741  27.762 1.00 239.47 ? 277 ASP D C   1 
ATOM   12994 O O   . ASP D 1 269 ? -52.882 94.331  28.671 1.00 260.11 ? 277 ASP D O   1 
ATOM   12995 C CB  . ASP D 1 269 ? -51.247 92.316  29.525 1.00 176.93 ? 277 ASP D CB  1 
ATOM   12996 C CG  . ASP D 1 269 ? -52.453 91.404  29.644 1.00 137.09 ? 277 ASP D CG  1 
ATOM   12997 O OD1 . ASP D 1 269 ? -52.819 90.788  28.629 1.00 98.79  ? 277 ASP D OD1 1 
ATOM   12998 O OD2 . ASP D 1 269 ? -53.015 91.323  30.752 1.00 106.54 ? 277 ASP D OD2 1 
ATOM   12999 N N   . PRO D 1 270 ? -52.764 93.767  26.493 1.00 187.20 ? 278 PRO D N   1 
ATOM   13000 C CA  . PRO D 1 270 ? -53.892 94.605  26.117 1.00 144.82 ? 278 PRO D CA  1 
ATOM   13001 C C   . PRO D 1 270 ? -55.027 94.260  27.075 1.00 129.09 ? 278 PRO D C   1 
ATOM   13002 O O   . PRO D 1 270 ? -55.880 95.088  27.297 1.00 83.47  ? 278 PRO D O   1 
ATOM   13003 C CB  . PRO D 1 270 ? -54.253 94.114  24.719 1.00 30.00  ? 278 PRO D CB  1 
ATOM   13004 C CG  . PRO D 1 270 ? -52.949 93.575  24.176 1.00 30.00  ? 278 PRO D CG  1 
ATOM   13005 C CD  . PRO D 1 270 ? -52.249 92.975  25.377 1.00 30.00  ? 278 PRO D CD  1 
ATOM   13006 N N   . ALA D 1 271 ? -54.998 93.040  27.602 1.00 146.48 ? 279 ALA D N   1 
ATOM   13007 C CA  . ALA D 1 271 ? -56.017 92.640  28.599 1.00 136.84 ? 279 ALA D CA  1 
ATOM   13008 C C   . ALA D 1 271 ? -55.934 93.619  29.770 1.00 159.91 ? 279 ALA D C   1 
ATOM   13009 O O   . ALA D 1 271 ? -56.996 94.090  30.217 1.00 151.47 ? 279 ALA D O   1 
ATOM   13010 C CB  . ALA D 1 271 ? -55.807 91.205  29.059 1.00 30.00  ? 279 ALA D CB  1 
ATOM   13011 N N   . THR D 1 272 ? -54.722 93.913  30.245 1.00 186.04 ? 280 THR D N   1 
ATOM   13012 C CA  . THR D 1 272 ? -54.549 94.926  31.316 1.00 166.52 ? 280 THR D CA  1 
ATOM   13013 C C   . THR D 1 272 ? -54.167 96.248  30.652 1.00 151.94 ? 280 THR D C   1 
ATOM   13014 O O   . THR D 1 272 ? -54.172 97.277  31.346 1.00 138.89 ? 280 THR D O   1 
ATOM   13015 C CB  . THR D 1 272 ? -53.484 94.477  32.319 1.00 132.54 ? 280 THR D CB  1 
ATOM   13016 O OG1 . THR D 1 272 ? -52.266 94.283  31.600 1.00 134.99 ? 280 THR D OG1 1 
ATOM   13017 C CG2 . THR D 1 272 ? -53.857 93.202  33.041 1.00 86.28  ? 280 THR D CG2 1 
ATOM   13018 N N   . GLY D 1 273 ? -53.851 96.211  29.356 1.00 157.36 ? 281 GLY D N   1 
ATOM   13019 C CA  . GLY D 1 273 ? -53.410 97.416  28.631 1.00 126.61 ? 281 GLY D CA  1 
ATOM   13020 C C   . GLY D 1 273 ? -52.087 97.914  29.170 1.00 152.55 ? 281 GLY D C   1 
ATOM   13021 O O   . GLY D 1 273 ? -51.625 98.968  28.699 1.00 146.59 ? 281 GLY D O   1 
ATOM   13022 N N   . LYS D 1 274 ? -51.483 97.176  30.103 1.00 167.02 ? 282 LYS D N   1 
ATOM   13023 C CA  . LYS D 1 274 ? -50.244 97.672  30.759 1.00 150.93 ? 282 LYS D CA  1 
ATOM   13024 C C   . LYS D 1 274 ? -49.041 96.843  30.317 1.00 162.52 ? 282 LYS D C   1 
ATOM   13025 O O   . LYS D 1 274 ? -49.230 95.913  29.517 1.00 176.78 ? 282 LYS D O   1 
ATOM   13026 C CB  . LYS D 1 274 ? -50.388 97.620  32.280 1.00 134.03 ? 282 LYS D CB  1 
ATOM   13027 C CG  . LYS D 1 274 ? -49.438 98.519  33.061 1.00 126.03 ? 282 LYS D CG  1 
ATOM   13028 C CD  . LYS D 1 274 ? -49.633 99.994  32.776 1.00 119.09 ? 282 LYS D CD  1 
ATOM   13029 C CE  . LYS D 1 274 ? -48.755 100.515 31.659 1.00 105.69 ? 282 LYS D CE  1 
ATOM   13030 N NZ  . LYS D 1 274 ? -47.326 100.528 32.050 1.00 114.56 ? 282 LYS D NZ  1 
ATOM   13031 N N   . GLU D 1 275 ? -47.861 97.155  30.850 1.00 151.48 ? 283 GLU D N   1 
ATOM   13032 C CA  . GLU D 1 275 ? -46.629 96.476  30.381 1.00 138.21 ? 283 GLU D CA  1 
ATOM   13033 C C   . GLU D 1 275 ? -46.222 95.347  31.325 1.00 146.04 ? 283 GLU D C   1 
ATOM   13034 O O   . GLU D 1 275 ? -46.222 95.577  32.547 1.00 179.43 ? 283 GLU D O   1 
ATOM   13035 C CB  . GLU D 1 275 ? -45.503 97.504  30.284 1.00 119.22 ? 283 GLU D CB  1 
ATOM   13036 C CG  . GLU D 1 275 ? -45.223 98.228  31.585 1.00 132.49 ? 283 GLU D CG  1 
ATOM   13037 C CD  . GLU D 1 275 ? -44.337 99.450  31.425 1.00 166.04 ? 283 GLU D CD  1 
ATOM   13038 O OE1 . GLU D 1 275 ? -44.141 99.887  30.274 1.00 132.54 ? 283 GLU D OE1 1 
ATOM   13039 O OE2 . GLU D 1 275 ? -43.845 99.960  32.450 1.00 175.65 ? 283 GLU D OE2 1 
ATOM   13040 N N   . ILE D 1 276 ? -45.914 94.168  30.778 1.00 160.34 ? 284 ILE D N   1 
ATOM   13041 C CA  . ILE D 1 276 ? -45.375 93.063  31.621 1.00 123.55 ? 284 ILE D CA  1 
ATOM   13042 C C   . ILE D 1 276 ? -43.864 93.203  31.494 1.00 106.51 ? 284 ILE D C   1 
ATOM   13043 O O   . ILE D 1 276 ? -43.384 93.300  30.355 1.00 86.04  ? 284 ILE D O   1 
ATOM   13044 C CB  . ILE D 1 276 ? -45.910 91.696  31.163 1.00 104.30 ? 284 ILE D CB  1 
ATOM   13045 C CG1 . ILE D 1 276 ? -47.432 91.716  31.010 1.00 96.42  ? 284 ILE D CG1 1 
ATOM   13046 C CG2 . ILE D 1 276 ? -45.453 90.597  32.107 1.00 82.72  ? 284 ILE D CG2 1 
ATOM   13047 C CD1 . ILE D 1 276 ? -48.021 90.395  30.587 1.00 64.02  ? 284 ILE D CD1 1 
ATOM   13048 N N   . LEU D 1 277 ? -43.145 93.211  32.610 1.00 86.03  ? 285 LEU D N   1 
ATOM   13049 C CA  . LEU D 1 277 ? -41.704 93.548  32.521 1.00 100.10 ? 285 LEU D CA  1 
ATOM   13050 C C   . LEU D 1 277 ? -40.763 92.362  32.714 1.00 120.07 ? 285 LEU D C   1 
ATOM   13051 O O   . LEU D 1 277 ? -41.040 91.518  33.581 1.00 168.37 ? 285 LEU D O   1 
ATOM   13052 C CB  . LEU D 1 277 ? -41.422 94.625  33.572 1.00 88.62  ? 285 LEU D CB  1 
ATOM   13053 C CG  . LEU D 1 277 ? -42.219 95.917  33.423 1.00 85.33  ? 285 LEU D CG  1 
ATOM   13054 C CD1 . LEU D 1 277 ? -42.058 96.789  34.655 1.00 78.83  ? 285 LEU D CD1 1 
ATOM   13055 C CD2 . LEU D 1 277 ? -41.785 96.672  32.180 1.00 59.19  ? 285 LEU D CD2 1 
ATOM   13056 N N   . TYR D 1 278 ? -39.699 92.307  31.920 1.00 87.76  ? 286 TYR D N   1 
ATOM   13057 C CA  . TYR D 1 278 ? -38.633 91.331  32.060 1.00 73.12  ? 286 TYR D CA  1 
ATOM   13058 C C   . TYR D 1 278 ? -38.281 91.195  33.536 1.00 87.04  ? 286 TYR D C   1 
ATOM   13059 O O   . TYR D 1 278 ? -37.914 92.187  34.162 1.00 99.73  ? 286 TYR D O   1 
ATOM   13060 C CB  . TYR D 1 278 ? -37.366 91.758  31.318 1.00 62.54  ? 286 TYR D CB  1 
ATOM   13061 C CG  . TYR D 1 278 ? -37.494 91.478  29.828 1.00 80.28  ? 286 TYR D CG  1 
ATOM   13062 C CD1 . TYR D 1 278 ? -37.655 90.180  29.335 1.00 86.31  ? 286 TYR D CD1 1 
ATOM   13063 C CD2 . TYR D 1 278 ? -37.511 92.538  28.922 1.00 101.80 ? 286 TYR D CD2 1 
ATOM   13064 C CE1 . TYR D 1 278 ? -37.831 89.961  27.973 1.00 97.55  ? 286 TYR D CE1 1 
ATOM   13065 C CE2 . TYR D 1 278 ? -37.665 92.331  27.563 1.00 127.08 ? 286 TYR D CE2 1 
ATOM   13066 C CZ  . TYR D 1 278 ? -37.810 91.037  27.088 1.00 122.56 ? 286 TYR D CZ  1 
ATOM   13067 O OH  . TYR D 1 278 ? -37.945 90.916  25.729 1.00 108.85 ? 286 TYR D OH  1 
ATOM   13068 N N   . ASN D 1 279 ? -38.299 89.951  34.039 1.00 93.94  ? 287 ASN D N   1 
ATOM   13069 C CA  . ASN D 1 279 ? -37.890 89.696  35.407 1.00 80.71  ? 287 ASN D CA  1 
ATOM   13070 C C   . ASN D 1 279 ? -36.508 89.043  35.496 1.00 82.58  ? 287 ASN D C   1 
ATOM   13071 O O   . ASN D 1 279 ? -36.054 88.668  36.576 1.00 88.71  ? 287 ASN D O   1 
ATOM   13072 C CB  . ASN D 1 279 ? -38.959 88.949  36.191 1.00 85.66  ? 287 ASN D CB  1 
ATOM   13073 C CG  . ASN D 1 279 ? -38.808 89.325  37.644 1.00 99.47  ? 287 ASN D CG  1 
ATOM   13074 O OD1 . ASN D 1 279 ? -37.855 90.032  37.990 1.00 108.51 ? 287 ASN D OD1 1 
ATOM   13075 N ND2 . ASN D 1 279 ? -39.736 88.920  38.501 1.00 130.49 ? 287 ASN D ND2 1 
ATOM   13076 N N   . LEU D 1 280 ? -35.818 88.976  34.359 1.00 75.69  ? 288 LEU D N   1 
ATOM   13077 C CA  . LEU D 1 280 ? -34.625 88.173  34.139 1.00 76.82  ? 288 LEU D CA  1 
ATOM   13078 C C   . LEU D 1 280 ? -33.541 88.555  35.136 1.00 75.44  ? 288 LEU D C   1 
ATOM   13079 O O   . LEU D 1 280 ? -32.823 87.685  35.609 1.00 64.14  ? 288 LEU D O   1 
ATOM   13080 C CB  . LEU D 1 280 ? -34.112 88.326  32.699 1.00 73.65  ? 288 LEU D CB  1 
ATOM   13081 C CG  . LEU D 1 280 ? -35.139 88.005  31.605 1.00 70.96  ? 288 LEU D CG  1 
ATOM   13082 C CD1 . LEU D 1 280 ? -34.617 88.283  30.206 1.00 93.41  ? 288 LEU D CD1 1 
ATOM   13083 C CD2 . LEU D 1 280 ? -35.628 86.578  31.692 1.00 56.24  ? 288 LEU D CD2 1 
ATOM   13084 N N   . GLU D 1 281 ? -33.428 89.847  35.443 1.00 74.04  ? 289 GLU D N   1 
ATOM   13085 C CA  . GLU D 1 281 ? -32.399 90.328  36.348 1.00 77.01  ? 289 GLU D CA  1 
ATOM   13086 C C   . GLU D 1 281 ? -32.494 89.641  37.718 1.00 83.26  ? 289 GLU D C   1 
ATOM   13087 O O   . GLU D 1 281 ? -31.513 89.083  38.230 1.00 78.87  ? 289 GLU D O   1 
ATOM   13088 C CB  . GLU D 1 281 ? -32.405 91.847  36.443 1.00 69.04  ? 289 GLU D CB  1 
ATOM   13089 C CG  . GLU D 1 281 ? -31.300 92.371  37.337 1.00 74.28  ? 289 GLU D CG  1 
ATOM   13090 C CD  . GLU D 1 281 ? -31.041 93.865  37.167 1.00 93.50  ? 289 GLU D CD  1 
ATOM   13091 O OE1 . GLU D 1 281 ? -32.040 94.620  37.279 1.00 74.92  ? 289 GLU D OE1 1 
ATOM   13092 O OE2 . GLU D 1 281 ? -29.856 94.265  36.962 1.00 98.48  ? 289 GLU D OE2 1 
ATOM   13093 N N   . SER D 1 282 ? -33.661 89.648  38.358 1.00 63.38  ? 290 SER D N   1 
ATOM   13094 C CA  . SER D 1 282 ? -33.637 89.013  39.672 1.00 71.87  ? 290 SER D CA  1 
ATOM   13095 C C   . SER D 1 282 ? -33.397 87.502  39.571 1.00 78.71  ? 290 SER D C   1 
ATOM   13096 O O   . SER D 1 282 ? -32.530 86.956  40.266 1.00 85.25  ? 290 SER D O   1 
ATOM   13097 C CB  . SER D 1 282 ? -34.805 89.364  40.579 1.00 68.84  ? 290 SER D CB  1 
ATOM   13098 O OG  . SER D 1 282 ? -35.933 88.577  40.213 1.00 92.38  ? 290 SER D OG  1 
ATOM   13099 N N   . LEU D 1 283 ? -34.057 86.834  38.621 1.00 62.17  ? 291 LEU D N   1 
ATOM   13100 C CA  . LEU D 1 283 ? -33.876 85.395  38.474 1.00 71.35  ? 291 LEU D CA  1 
ATOM   13101 C C   . LEU D 1 283 ? -32.401 85.033  38.309 1.00 83.76  ? 291 LEU D C   1 
ATOM   13102 O O   . LEU D 1 283 ? -31.846 84.251  39.094 1.00 95.28  ? 291 LEU D O   1 
ATOM   13103 C CB  . LEU D 1 283 ? -34.722 84.901  37.301 1.00 57.08  ? 291 LEU D CB  1 
ATOM   13104 C CG  . LEU D 1 283 ? -36.216 85.061  37.584 1.00 46.45  ? 291 LEU D CG  1 
ATOM   13105 C CD1 . LEU D 1 283 ? -37.110 84.757  36.432 1.00 31.49  ? 291 LEU D CD1 1 
ATOM   13106 C CD2 . LEU D 1 283 ? -36.526 84.215  38.870 1.00 38.79  ? 291 LEU D CD2 1 
ATOM   13107 N N   . ILE D 1 284 ? -31.778 85.602  37.272 1.00 67.68  ? 292 ILE D N   1 
ATOM   13108 C CA  . ILE D 1 284 ? -30.403 85.259  36.961 1.00 64.85  ? 292 ILE D CA  1 
ATOM   13109 C C   . ILE D 1 284 ? -29.499 85.629  38.132 1.00 67.61  ? 292 ILE D C   1 
ATOM   13110 O O   . ILE D 1 284 ? -28.729 84.785  38.598 1.00 85.03  ? 292 ILE D O   1 
ATOM   13111 C CB  . ILE D 1 284 ? -29.963 85.890  35.640 1.00 52.66  ? 292 ILE D CB  1 
ATOM   13112 C CG1 . ILE D 1 284 ? -30.744 85.241  34.482 1.00 63.86  ? 292 ILE D CG1 1 
ATOM   13113 C CG2 . ILE D 1 284 ? -28.462 85.703  35.478 1.00 48.28  ? 292 ILE D CG2 1 
ATOM   13114 C CD1 . ILE D 1 284 ? -30.755 86.001  33.159 1.00 60.36  ? 292 ILE D CD1 1 
ATOM   13115 N N   . ASN D 1 285 ? -29.695 86.833  38.666 1.00 63.70  ? 293 ASN D N   1 
ATOM   13116 C CA  . ASN D 1 285 ? -28.903 87.255  39.806 1.00 72.73  ? 293 ASN D CA  1 
ATOM   13117 C C   . ASN D 1 285 ? -29.043 86.261  40.946 1.00 86.89  ? 293 ASN D C   1 
ATOM   13118 O O   . ASN D 1 285 ? -28.030 85.835  41.524 1.00 105.08 ? 293 ASN D O   1 
ATOM   13119 C CB  . ASN D 1 285 ? -29.085 88.713  40.184 1.00 67.80  ? 293 ASN D CB  1 
ATOM   13120 C CG  . ASN D 1 285 ? -28.424 89.596  39.154 1.00 98.68  ? 293 ASN D CG  1 
ATOM   13121 O OD1 . ASN D 1 285 ? -27.341 89.271  38.633 1.00 96.04  ? 293 ASN D OD1 1 
ATOM   13122 N ND2 . ASN D 1 285 ? -29.109 90.680  38.804 1.00 97.43  ? 293 ASN D ND2 1 
ATOM   13123 N N   . SER D 1 286 ? -30.290 85.859  41.234 1.00 66.84  ? 294 SER D N   1 
ATOM   13124 C CA  . SER D 1 286 ? -30.504 84.970  42.367 1.00 85.14  ? 294 SER D CA  1 
ATOM   13125 C C   . SER D 1 286 ? -29.914 83.593  42.082 1.00 79.65  ? 294 SER D C   1 
ATOM   13126 O O   . SER D 1 286 ? -29.433 82.927  42.990 1.00 96.81  ? 294 SER D O   1 
ATOM   13127 C CB  . SER D 1 286 ? -31.940 84.884  42.771 1.00 77.87  ? 294 SER D CB  1 
ATOM   13128 O OG  . SER D 1 286 ? -32.472 86.193  42.925 1.00 76.53  ? 294 SER D OG  1 
ATOM   13129 N N   . ALA D 1 287 ? -29.932 83.207  40.809 1.00 71.99  ? 295 ALA D N   1 
ATOM   13130 C CA  . ALA D 1 287 ? -29.425 81.911  40.401 1.00 84.04  ? 295 ALA D CA  1 
ATOM   13131 C C   . ALA D 1 287 ? -27.931 81.830  40.700 1.00 79.03  ? 295 ALA D C   1 
ATOM   13132 O O   . ALA D 1 287 ? -27.459 80.866  41.313 1.00 70.68  ? 295 ALA D O   1 
ATOM   13133 C CB  . ALA D 1 287 ? -29.705 81.678  38.925 1.00 82.94  ? 295 ALA D CB  1 
ATOM   13134 N N   . VAL D 1 288 ? -27.211 82.864  40.261 1.00 74.04  ? 296 VAL D N   1 
ATOM   13135 C CA  . VAL D 1 288 ? -25.784 82.884  40.479 1.00 82.89  ? 296 VAL D CA  1 
ATOM   13136 C C   . VAL D 1 288 ? -25.471 82.900  41.967 1.00 80.55  ? 296 VAL D C   1 
ATOM   13137 O O   . VAL D 1 288 ? -24.570 82.167  42.428 1.00 82.04  ? 296 VAL D O   1 
ATOM   13138 C CB  . VAL D 1 288 ? -25.140 84.081  39.784 1.00 96.55  ? 296 VAL D CB  1 
ATOM   13139 C CG1 . VAL D 1 288 ? -23.667 84.142  40.161 1.00 113.93 ? 296 VAL D CG1 1 
ATOM   13140 C CG2 . VAL D 1 288 ? -25.332 83.954  38.281 1.00 86.94  ? 296 VAL D CG2 1 
ATOM   13141 N N   . PHE D 1 289 ? -26.248 83.724  42.686 1.00 71.99  ? 297 PHE D N   1 
ATOM   13142 C CA  . PHE D 1 289 ? -25.999 83.878  44.115 1.00 98.42  ? 297 PHE D CA  1 
ATOM   13143 C C   . PHE D 1 289 ? -27.291 84.348  44.773 1.00 88.03  ? 297 PHE D C   1 
ATOM   13144 O O   . PHE D 1 289 ? -27.852 85.357  44.351 1.00 104.20 ? 297 PHE D O   1 
ATOM   13145 C CB  . PHE D 1 289 ? -24.830 84.797  44.543 1.00 82.87  ? 297 PHE D CB  1 
ATOM   13146 C CG  . PHE D 1 289 ? -24.584 84.706  46.039 1.00 90.97  ? 297 PHE D CG  1 
ATOM   13147 C CD1 . PHE D 1 289 ? -23.747 83.729  46.573 1.00 130.12 ? 297 PHE D CD1 1 
ATOM   13148 C CD2 . PHE D 1 289 ? -25.262 85.511  46.934 1.00 107.84 ? 297 PHE D CD2 1 
ATOM   13149 C CE1 . PHE D 1 289 ? -23.568 83.610  47.954 1.00 117.75 ? 297 PHE D CE1 1 
ATOM   13150 C CE2 . PHE D 1 289 ? -25.074 85.381  48.311 1.00 102.18 ? 297 PHE D CE2 1 
ATOM   13151 C CZ  . PHE D 1 289 ? -24.235 84.436  48.822 1.00 99.68  ? 297 PHE D CZ  1 
ATOM   13152 N N   . PRO D 1 290 ? -27.799 83.700  45.850 1.00 71.60  ? 298 PRO D N   1 
ATOM   13153 C CA  . PRO D 1 290 ? -27.163 82.554  46.540 1.00 82.93  ? 298 PRO D CA  1 
ATOM   13154 C C   . PRO D 1 290 ? -27.615 81.169  46.043 1.00 84.25  ? 298 PRO D C   1 
ATOM   13155 O O   . PRO D 1 290 ? -27.919 80.198  46.762 1.00 86.89  ? 298 PRO D O   1 
ATOM   13156 C CB  . PRO D 1 290 ? -27.728 82.860  47.910 1.00 77.69  ? 298 PRO D CB  1 
ATOM   13157 C CG  . PRO D 1 290 ? -29.218 83.073  47.556 1.00 72.90  ? 298 PRO D CG  1 
ATOM   13158 C CD  . PRO D 1 290 ? -29.102 84.076  46.423 1.00 57.99  ? 298 PRO D CD  1 
ATOM   13159 N N   . GLY D 1 291 ? -27.722 81.066  44.740 1.00 67.85  ? 299 GLY D N   1 
ATOM   13160 C CA  . GLY D 1 291 ? -28.241 79.822  44.229 1.00 63.90  ? 299 GLY D CA  1 
ATOM   13161 C C   . GLY D 1 291 ? -27.114 78.826  44.078 1.00 70.83  ? 299 GLY D C   1 
ATOM   13162 O O   . GLY D 1 291 ? -27.173 77.757  44.679 1.00 105.28 ? 299 GLY D O   1 
ATOM   13163 N N   . LEU D 1 292 ? -26.108 79.187  43.275 1.00 60.03  ? 300 LEU D N   1 
ATOM   13164 C CA  . LEU D 1 292 ? -25.141 78.205  42.805 1.00 53.80  ? 300 LEU D CA  1 
ATOM   13165 C C   . LEU D 1 292 ? -23.755 78.515  43.355 1.00 55.95  ? 300 LEU D C   1 
ATOM   13166 O O   . LEU D 1 292 ? -22.988 77.605  43.666 1.00 56.30  ? 300 LEU D O   1 
ATOM   13167 C CB  . LEU D 1 292 ? -25.099 78.190  41.284 1.00 54.60  ? 300 LEU D CB  1 
ATOM   13168 C CG  . LEU D 1 292 ? -26.378 77.678  40.611 1.00 66.03  ? 300 LEU D CG  1 
ATOM   13169 C CD1 . LEU D 1 292 ? -26.627 78.102  39.112 1.00 44.66  ? 300 LEU D CD1 1 
ATOM   13170 C CD2 . LEU D 1 292 ? -26.294 76.175  40.857 1.00 54.99  ? 300 LEU D CD2 1 
ATOM   13171 N N   . GLN D 1 293 ? -23.392 79.801  43.407 1.00 61.81  ? 301 GLN D N   1 
ATOM   13172 C CA  . GLN D 1 293 ? -22.001 80.122  43.678 1.00 77.23  ? 301 GLN D CA  1 
ATOM   13173 C C   . GLN D 1 293 ? -21.846 80.562  45.132 1.00 94.43  ? 301 GLN D C   1 
ATOM   13174 O O   . GLN D 1 293 ? -22.841 80.762  45.828 1.00 113.62 ? 301 GLN D O   1 
ATOM   13175 C CB  . GLN D 1 293 ? -21.488 81.137  42.658 1.00 81.83  ? 301 GLN D CB  1 
ATOM   13176 C CG  . GLN D 1 293 ? -21.540 80.587  41.236 1.00 84.94  ? 301 GLN D CG  1 
ATOM   13177 C CD  . GLN D 1 293 ? -20.732 81.413  40.270 1.00 92.06  ? 301 GLN D CD  1 
ATOM   13178 O OE1 . GLN D 1 293 ? -20.409 80.940  39.174 1.00 85.12  ? 301 GLN D OE1 1 
ATOM   13179 N NE2 . GLN D 1 293 ? -20.370 82.621  40.699 1.00 80.75  ? 301 GLN D NE2 1 
ATOM   13180 N N   . GLY D 1 294 ? -20.595 80.668  45.598 1.00 100.39 ? 302 GLY D N   1 
ATOM   13181 C CA  . GLY D 1 294 ? -20.353 81.382  46.836 1.00 106.13 ? 302 GLY D CA  1 
ATOM   13182 C C   . GLY D 1 294 ? -19.606 82.682  46.554 1.00 114.62 ? 302 GLY D C   1 
ATOM   13183 O O   . GLY D 1 294 ? -19.971 83.479  45.678 1.00 117.52 ? 302 GLY D O   1 
ATOM   13184 N N   . GLY D 1 295 ? -18.491 82.824  47.265 1.00 134.16 ? 303 GLY D N   1 
ATOM   13185 C CA  . GLY D 1 295 ? -17.645 84.000  47.168 1.00 136.93 ? 303 GLY D CA  1 
ATOM   13186 C C   . GLY D 1 295 ? -17.254 84.282  45.731 1.00 105.94 ? 303 GLY D C   1 
ATOM   13187 O O   . GLY D 1 295 ? -16.698 83.420  45.073 1.00 120.02 ? 303 GLY D O   1 
ATOM   13188 N N   . PRO D 1 296 ? -17.510 85.507  45.223 1.00 90.78  ? 304 PRO D N   1 
ATOM   13189 C CA  . PRO D 1 296 ? -17.066 85.880  43.883 1.00 78.15  ? 304 PRO D CA  1 
ATOM   13190 C C   . PRO D 1 296 ? -15.539 85.789  43.831 1.00 87.74  ? 304 PRO D C   1 
ATOM   13191 O O   . PRO D 1 296 ? -14.865 86.051  44.860 1.00 89.25  ? 304 PRO D O   1 
ATOM   13192 C CB  . PRO D 1 296 ? -17.537 87.344  43.843 1.00 84.43  ? 304 PRO D CB  1 
ATOM   13193 C CG  . PRO D 1 296 ? -18.774 87.333  44.703 1.00 129.41 ? 304 PRO D CG  1 
ATOM   13194 C CD  . PRO D 1 296 ? -18.252 86.576  45.908 1.00 119.96 ? 304 PRO D CD  1 
ATOM   13195 N N   . HIS D 1 297 ? -15.001 85.443  42.629 1.00 68.56  ? 305 HIS D N   1 
ATOM   13196 C CA  . HIS D 1 297 ? -13.543 85.417  42.488 1.00 75.55  ? 305 HIS D CA  1 
ATOM   13197 C C   . HIS D 1 297 ? -13.048 86.790  42.060 1.00 85.49  ? 305 HIS D C   1 
ATOM   13198 O O   . HIS D 1 297 ? -12.906 87.007  40.848 1.00 59.59  ? 305 HIS D O   1 
ATOM   13199 C CB  . HIS D 1 297 ? -13.041 84.307  41.554 1.00 54.93  ? 305 HIS D CB  1 
ATOM   13200 C CG  . HIS D 1 297 ? -13.267 82.982  42.176 1.00 67.46  ? 305 HIS D CG  1 
ATOM   13201 N ND1 . HIS D 1 297 ? -13.105 81.790  41.538 1.00 64.83  ? 305 HIS D ND1 1 
ATOM   13202 C CD2 . HIS D 1 297 ? -13.659 82.655  43.423 1.00 94.55  ? 305 HIS D CD2 1 
ATOM   13203 C CE1 . HIS D 1 297 ? -13.416 80.790  42.367 1.00 69.44  ? 305 HIS D CE1 1 
ATOM   13204 N NE2 . HIS D 1 297 ? -13.720 81.282  43.519 1.00 85.39  ? 305 HIS D NE2 1 
ATOM   13205 N N   . ASN D 1 298 ? -12.795 87.706  43.030 1.00 70.65  ? 306 ASN D N   1 
ATOM   13206 C CA  . ASN D 1 298 ? -12.704 89.093  42.596 1.00 66.55  ? 306 ASN D CA  1 
ATOM   13207 C C   . ASN D 1 298 ? -11.489 89.320  41.709 1.00 75.71  ? 306 ASN D C   1 
ATOM   13208 O O   . ASN D 1 298 ? -11.525 90.161  40.807 1.00 70.58  ? 306 ASN D O   1 
ATOM   13209 C CB  . ASN D 1 298 ? -12.726 90.051  43.763 1.00 75.36  ? 306 ASN D CB  1 
ATOM   13210 C CG  . ASN D 1 298 ? -14.066 90.068  44.458 1.00 93.54  ? 306 ASN D CG  1 
ATOM   13211 O OD1 . ASN D 1 298 ? -15.042 90.620  43.907 1.00 46.42  ? 306 ASN D OD1 1 
ATOM   13212 N ND2 . ASN D 1 298 ? -14.080 89.537  45.687 1.00 112.32 ? 306 ASN D ND2 1 
ATOM   13213 N N   . HIS D 1 299 ? -10.421 88.566  41.978 1.00 64.08  ? 307 HIS D N   1 
ATOM   13214 C CA  . HIS D 1 299 ? -9.222  88.644  41.175 1.00 63.47  ? 307 HIS D CA  1 
ATOM   13215 C C   . HIS D 1 299 ? -9.507  88.255  39.723 1.00 69.15  ? 307 HIS D C   1 
ATOM   13216 O O   . HIS D 1 299 ? -8.894  88.812  38.808 1.00 63.56  ? 307 HIS D O   1 
ATOM   13217 C CB  . HIS D 1 299 ? -8.169  87.744  41.796 1.00 72.07  ? 307 HIS D CB  1 
ATOM   13218 C CG  . HIS D 1 299 ? -8.591  86.319  41.903 1.00 68.99  ? 307 HIS D CG  1 
ATOM   13219 N ND1 . HIS D 1 299 ? -9.514  85.828  42.797 1.00 68.40  ? 307 HIS D ND1 1 
ATOM   13220 C CD2 . HIS D 1 299 ? -8.171  85.298  41.197 1.00 73.86  ? 307 HIS D CD2 1 
ATOM   13221 C CE1 . HIS D 1 299 ? -9.645  84.524  42.603 1.00 67.32  ? 307 HIS D CE1 1 
ATOM   13222 N NE2 . HIS D 1 299 ? -8.809  84.177  41.663 1.00 81.70  ? 307 HIS D NE2 1 
ATOM   13223 N N   . ALA D 1 300 ? -10.451 87.317  39.522 1.00 71.36  ? 308 ALA D N   1 
ATOM   13224 C CA  . ALA D 1 300 ? -10.904 86.982  38.176 1.00 69.92  ? 308 ALA D CA  1 
ATOM   13225 C C   . ALA D 1 300 ? -11.736 88.110  37.570 1.00 71.67  ? 308 ALA D C   1 
ATOM   13226 O O   . ALA D 1 300 ? -11.572 88.405  36.378 1.00 49.55  ? 308 ALA D O   1 
ATOM   13227 C CB  . ALA D 1 300 ? -11.674 85.693  38.139 1.00 60.57  ? 308 ALA D CB  1 
ATOM   13228 N N   . ILE D 1 301 ? -12.576 88.752  38.407 1.00 69.30  ? 309 ILE D N   1 
ATOM   13229 C CA  . ILE D 1 301 ? -13.456 89.799  37.902 1.00 86.34  ? 309 ILE D CA  1 
ATOM   13230 C C   . ILE D 1 301 ? -12.604 90.984  37.446 1.00 79.34  ? 309 ILE D C   1 
ATOM   13231 O O   . ILE D 1 301 ? -12.863 91.600  36.389 1.00 71.04  ? 309 ILE D O   1 
ATOM   13232 C CB  . ILE D 1 301 ? -14.539 90.206  38.913 1.00 75.22  ? 309 ILE D CB  1 
ATOM   13233 C CG1 . ILE D 1 301 ? -15.502 89.091  39.145 1.00 80.55  ? 309 ILE D CG1 1 
ATOM   13234 C CG2 . ILE D 1 301 ? -15.347 91.356  38.323 1.00 69.09  ? 309 ILE D CG2 1 
ATOM   13235 C CD1 . ILE D 1 301 ? -16.363 89.303  40.366 1.00 75.63  ? 309 ILE D CD1 1 
ATOM   13236 N N   . ALA D 1 302 ? -11.538 91.227  38.223 1.00 53.57  ? 310 ALA D N   1 
ATOM   13237 C CA  . ALA D 1 302 ? -10.569 92.262  37.859 1.00 71.13  ? 310 ALA D CA  1 
ATOM   13238 C C   . ALA D 1 302 ? -9.987  91.973  36.468 1.00 71.70  ? 310 ALA D C   1 
ATOM   13239 O O   . ALA D 1 302 ? -9.919  92.847  35.595 1.00 56.38  ? 310 ALA D O   1 
ATOM   13240 C CB  . ALA D 1 302 ? -9.481  92.336  38.917 1.00 56.10  ? 310 ALA D CB  1 
ATOM   13241 N N   . GLY D 1 303 ? -9.530  90.722  36.286 1.00 51.29  ? 311 GLY D N   1 
ATOM   13242 C CA  . GLY D 1 303 ? -8.948  90.301  35.029 1.00 48.37  ? 311 GLY D CA  1 
ATOM   13243 C C   . GLY D 1 303 ? -9.924  90.502  33.882 1.00 48.65  ? 311 GLY D C   1 
ATOM   13244 O O   . GLY D 1 303 ? -9.525  90.908  32.796 1.00 48.68  ? 311 GLY D O   1 
ATOM   13245 N N   . VAL D 1 304 ? -11.202 90.226  34.140 1.00 45.80  ? 312 VAL D N   1 
ATOM   13246 C CA  . VAL D 1 304 ? -12.219 90.367  33.110 1.00 68.12  ? 312 VAL D CA  1 
ATOM   13247 C C   . VAL D 1 304 ? -12.361 91.837  32.743 1.00 67.14  ? 312 VAL D C   1 
ATOM   13248 O O   . VAL D 1 304 ? -12.469 92.187  31.556 1.00 47.18  ? 312 VAL D O   1 
ATOM   13249 C CB  . VAL D 1 304 ? -13.569 89.797  33.577 1.00 64.98  ? 312 VAL D CB  1 
ATOM   13250 C CG1 . VAL D 1 304 ? -14.719 90.080  32.557 1.00 47.39  ? 312 VAL D CG1 1 
ATOM   13251 C CG2 . VAL D 1 304 ? -13.356 88.323  33.928 1.00 69.17  ? 312 VAL D CG2 1 
ATOM   13252 N N   . ALA D 1 305 ? -12.386 92.667  33.791 1.00 65.81  ? 313 ALA D N   1 
ATOM   13253 C CA  . ALA D 1 305 ? -12.498 94.096  33.583 1.00 67.90  ? 313 ALA D CA  1 
ATOM   13254 C C   . ALA D 1 305 ? -11.367 94.530  32.642 1.00 60.53  ? 313 ALA D C   1 
ATOM   13255 O O   . ALA D 1 305 ? -11.641 95.115  31.597 1.00 60.43  ? 313 ALA D O   1 
ATOM   13256 C CB  . ALA D 1 305 ? -12.480 94.799  34.920 1.00 78.33  ? 313 ALA D CB  1 
ATOM   13257 N N   . VAL D 1 306 ? -10.123 94.168  32.979 1.00 45.90  ? 314 VAL D N   1 
ATOM   13258 C CA  . VAL D 1 306 ? -8.953  94.539  32.213 1.00 55.20  ? 314 VAL D CA  1 
ATOM   13259 C C   . VAL D 1 306 ? -9.114  94.118  30.753 1.00 54.80  ? 314 VAL D C   1 
ATOM   13260 O O   . VAL D 1 306 ? -8.840  94.896  29.825 1.00 61.15  ? 314 VAL D O   1 
ATOM   13261 C CB  . VAL D 1 306 ? -7.642  93.989  32.794 1.00 70.76  ? 314 VAL D CB  1 
ATOM   13262 C CG1 . VAL D 1 306 ? -6.551  94.243  31.777 1.00 90.86  ? 314 VAL D CG1 1 
ATOM   13263 C CG2 . VAL D 1 306 ? -7.274  94.622  34.140 1.00 60.36  ? 314 VAL D CG2 1 
ATOM   13264 N N   . ALA D 1 307 ? -9.591  92.887  30.570 1.00 62.15  ? 315 ALA D N   1 
ATOM   13265 C CA  . ALA D 1 307 ? -9.860  92.338  29.242 1.00 83.79  ? 315 ALA D CA  1 
ATOM   13266 C C   . ALA D 1 307 ? -10.864 93.181  28.449 1.00 81.75  ? 315 ALA D C   1 
ATOM   13267 O O   . ALA D 1 307 ? -10.659 93.421  27.244 1.00 77.94  ? 315 ALA D O   1 
ATOM   13268 C CB  . ALA D 1 307 ? -10.330 90.919  29.352 1.00 63.43  ? 315 ALA D CB  1 
ATOM   13269 N N   . LEU D 1 308 ? -11.953 93.572  29.144 1.00 66.07  ? 316 LEU D N   1 
ATOM   13270 C CA  . LEU D 1 308 ? -13.037 94.315  28.527 1.00 68.61  ? 316 LEU D CA  1 
ATOM   13271 C C   . LEU D 1 308 ? -12.514 95.668  28.058 1.00 85.75  ? 316 LEU D C   1 
ATOM   13272 O O   . LEU D 1 308 ? -12.886 96.158  26.977 1.00 72.19  ? 316 LEU D O   1 
ATOM   13273 C CB  . LEU D 1 308 ? -14.161 94.451  29.544 1.00 63.84  ? 316 LEU D CB  1 
ATOM   13274 C CG  . LEU D 1 308 ? -15.026 93.199  29.737 1.00 74.66  ? 316 LEU D CG  1 
ATOM   13275 C CD1 . LEU D 1 308 ? -15.931 93.343  30.926 1.00 80.83  ? 316 LEU D CD1 1 
ATOM   13276 C CD2 . LEU D 1 308 ? -15.904 93.064  28.524 1.00 70.19  ? 316 LEU D CD2 1 
ATOM   13277 N N   . LYS D 1 309 ? -11.653 96.267  28.894 1.00 87.48  ? 317 LYS D N   1 
ATOM   13278 C CA  . LYS D 1 309 ? -11.054 97.537  28.550 1.00 82.30  ? 317 LYS D CA  1 
ATOM   13279 C C   . LYS D 1 309 ? -10.289 97.345  27.256 1.00 68.35  ? 317 LYS D C   1 
ATOM   13280 O O   . LYS D 1 309 ? -10.521 98.128  26.363 1.00 64.02  ? 317 LYS D O   1 
ATOM   13281 C CB  . LYS D 1 309 ? -10.165 98.220  29.584 1.00 68.41  ? 317 LYS D CB  1 
ATOM   13282 C CG  . LYS D 1 309 ? -9.526  99.457  28.840 1.00 60.61  ? 317 LYS D CG  1 
ATOM   13283 C CD  . LYS D 1 309 ? -8.810  100.528 29.651 1.00 72.43  ? 317 LYS D CD  1 
ATOM   13284 C CE  . LYS D 1 309 ? -9.170  101.897 29.161 1.00 72.88  ? 317 LYS D CE  1 
ATOM   13285 N NZ  . LYS D 1 309 ? -8.993  102.890 30.226 1.00 116.25 ? 317 LYS D NZ  1 
ATOM   13286 N N   . GLN D 1 310 ? -9.479  96.285  27.158 1.00 58.97  ? 318 GLN D N   1 
ATOM   13287 C CA  . GLN D 1 310 ? -8.712  96.062  25.941 1.00 84.00  ? 318 GLN D CA  1 
ATOM   13288 C C   . GLN D 1 310 ? -9.630  95.831  24.750 1.00 86.22  ? 318 GLN D C   1 
ATOM   13289 O O   . GLN D 1 310 ? -9.291  96.245  23.648 1.00 65.80  ? 318 GLN D O   1 
ATOM   13290 C CB  . GLN D 1 310 ? -7.830  94.821  25.956 1.00 99.99  ? 318 GLN D CB  1 
ATOM   13291 C CG  . GLN D 1 310 ? -6.767  94.876  27.030 1.00 115.95 ? 318 GLN D CG  1 
ATOM   13292 C CD  . GLN D 1 310 ? -6.102  93.530  27.142 1.00 163.35 ? 318 GLN D CD  1 
ATOM   13293 O OE1 . GLN D 1 310 ? -5.243  93.352  28.011 1.00 205.92 ? 318 GLN D OE1 1 
ATOM   13294 N NE2 . GLN D 1 310 ? -6.452  92.579  26.272 1.00 142.52 ? 318 GLN D NE2 1 
ATOM   13295 N N   . ALA D 1 311 ? -10.782 95.192  25.002 1.00 102.52 ? 319 ALA D N   1 
ATOM   13296 C CA  . ALA D 1 311 ? -11.731 94.867  23.953 1.00 79.65  ? 319 ALA D CA  1 
ATOM   13297 C C   . ALA D 1 311 ? -12.254 96.120  23.264 1.00 75.39  ? 319 ALA D C   1 
ATOM   13298 O O   . ALA D 1 311 ? -12.722 96.045  22.139 1.00 86.73  ? 319 ALA D O   1 
ATOM   13299 C CB  . ALA D 1 311 ? -12.864 94.041  24.496 1.00 54.40  ? 319 ALA D CB  1 
ATOM   13300 N N   . MET D 1 312 ? -12.212 97.265  23.946 1.00 79.60  ? 320 MET D N   1 
ATOM   13301 C CA  . MET D 1 312 ? -12.802 98.473  23.384 1.00 87.23  ? 320 MET D CA  1 
ATOM   13302 C C   . MET D 1 312 ? -11.739 99.329  22.675 1.00 95.68  ? 320 MET D C   1 
ATOM   13303 O O   . MET D 1 312 ? -12.062 100.396 22.186 1.00 127.42 ? 320 MET D O   1 
ATOM   13304 C CB  . MET D 1 312 ? -13.500 99.264  24.497 1.00 82.74  ? 320 MET D CB  1 
ATOM   13305 C CG  . MET D 1 312 ? -14.794 98.650  24.970 1.00 103.00 ? 320 MET D CG  1 
ATOM   13306 S SD  . MET D 1 312 ? -15.556 99.348  26.460 1.00 86.85  ? 320 MET D SD  1 
ATOM   13307 C CE  . MET D 1 312 ? -14.291 99.250  27.731 1.00 62.06  ? 320 MET D CE  1 
ATOM   13308 N N   . THR D 1 313 ? -10.482 98.870  22.595 1.00 87.60  ? 321 THR D N   1 
ATOM   13309 C CA  . THR D 1 313 ? -9.424  99.542  21.850 1.00 83.33  ? 321 THR D CA  1 
ATOM   13310 C C   . THR D 1 313 ? -9.497  99.228  20.347 1.00 91.37  ? 321 THR D C   1 
ATOM   13311 O O   . THR D 1 313 ? -10.065 98.228  19.888 1.00 86.39  ? 321 THR D O   1 
ATOM   13312 C CB  . THR D 1 313 ? -8.064  99.112  22.405 1.00 105.05 ? 321 THR D CB  1 
ATOM   13313 O OG1 . THR D 1 313 ? -7.745  97.812  21.898 1.00 100.46 ? 321 THR D OG1 1 
ATOM   13314 C CG2 . THR D 1 313 ? -8.021  99.145  23.930 1.00 103.69 ? 321 THR D CG2 1 
ATOM   13315 N N   . LEU D 1 314 ? -8.882  100.110 19.553 1.00 85.47  ? 322 LEU D N   1 
ATOM   13316 C CA  . LEU D 1 314 ? -8.931  99.961  18.112 1.00 78.09  ? 322 LEU D CA  1 
ATOM   13317 C C   . LEU D 1 314 ? -8.067  98.780  17.728 1.00 72.37  ? 322 LEU D C   1 
ATOM   13318 O O   . LEU D 1 314 ? -8.447  98.065  16.790 1.00 59.89  ? 322 LEU D O   1 
ATOM   13319 C CB  . LEU D 1 314 ? -8.478  101.250 17.420 1.00 94.01  ? 322 LEU D CB  1 
ATOM   13320 C CG  . LEU D 1 314 ? -8.061  101.206 15.944 1.00 89.47  ? 322 LEU D CG  1 
ATOM   13321 C CD1 . LEU D 1 314 ? -9.034  100.775 14.867 1.00 77.46  ? 322 LEU D CD1 1 
ATOM   13322 C CD2 . LEU D 1 314 ? -7.863  102.674 15.677 1.00 69.50  ? 322 LEU D CD2 1 
ATOM   13323 N N   . GLU D 1 315 ? -6.967  98.585  18.496 1.00 76.19  ? 323 GLU D N   1 
ATOM   13324 C CA  . GLU D 1 315 ? -6.056  97.466  18.273 1.00 96.99  ? 323 GLU D CA  1 
ATOM   13325 C C   . GLU D 1 315 ? -6.809  96.138  18.331 1.00 84.51  ? 323 GLU D C   1 
ATOM   13326 O O   . GLU D 1 315 ? -6.556  95.285  17.475 1.00 70.92  ? 323 GLU D O   1 
ATOM   13327 C CB  . GLU D 1 315 ? -4.941  97.259  19.297 1.00 108.80 ? 323 GLU D CB  1 
ATOM   13328 C CG  . GLU D 1 315 ? -3.841  98.309  19.238 1.00 102.07 ? 323 GLU D CG  1 
ATOM   13329 C CD  . GLU D 1 315 ? -4.320  99.617  19.794 1.00 105.70 ? 323 GLU D CD  1 
ATOM   13330 O OE1 . GLU D 1 315 ? -5.512  99.850  20.153 1.00 134.18 ? 323 GLU D OE1 1 
ATOM   13331 O OE2 . GLU D 1 315 ? -3.355  100.398 19.916 1.00 80.76  ? 323 GLU D OE2 1 
ATOM   13332 N N   . PHE D 1 316 ? -7.678  95.997  19.355 1.00 68.02  ? 324 PHE D N   1 
ATOM   13333 C CA  . PHE D 1 316 ? -8.589  94.861  19.478 1.00 85.84  ? 324 PHE D CA  1 
ATOM   13334 C C   . PHE D 1 316 ? -9.437  94.691  18.204 1.00 103.31 ? 324 PHE D C   1 
ATOM   13335 O O   . PHE D 1 316 ? -9.455  93.588  17.653 1.00 90.01  ? 324 PHE D O   1 
ATOM   13336 C CB  . PHE D 1 316 ? -9.488  94.923  20.727 1.00 76.71  ? 324 PHE D CB  1 
ATOM   13337 C CG  . PHE D 1 316 ? -10.260 93.654  21.096 1.00 74.62  ? 324 PHE D CG  1 
ATOM   13338 C CD1 . PHE D 1 316 ? -9.701  92.708  21.940 1.00 95.66  ? 324 PHE D CD1 1 
ATOM   13339 C CD2 . PHE D 1 316 ? -11.585 93.447  20.698 1.00 87.31  ? 324 PHE D CD2 1 
ATOM   13340 C CE1 . PHE D 1 316 ? -10.430 91.575  22.301 1.00 111.23 ? 324 PHE D CE1 1 
ATOM   13341 C CE2 . PHE D 1 316 ? -12.294 92.290  21.018 1.00 76.34  ? 324 PHE D CE2 1 
ATOM   13342 C CZ  . PHE D 1 316 ? -11.707 91.341  21.801 1.00 80.22  ? 324 PHE D CZ  1 
ATOM   13343 N N   . LYS D 1 317 ? -10.152 95.755  17.764 1.00 106.15 ? 325 LYS D N   1 
ATOM   13344 C CA  . LYS D 1 317 ? -11.076 95.691  16.629 1.00 104.82 ? 325 LYS D CA  1 
ATOM   13345 C C   . LYS D 1 317 ? -10.313 95.189  15.393 1.00 108.47 ? 325 LYS D C   1 
ATOM   13346 O O   . LYS D 1 317 ? -10.770 94.332  14.624 1.00 88.65  ? 325 LYS D O   1 
ATOM   13347 C CB  . LYS D 1 317 ? -11.782 97.052  16.498 1.00 106.99 ? 325 LYS D CB  1 
ATOM   13348 C CG  . LYS D 1 317 ? -13.280 97.156  16.103 1.00 121.90 ? 325 LYS D CG  1 
ATOM   13349 C CD  . LYS D 1 317 ? -14.032 98.254  16.895 1.00 133.15 ? 325 LYS D CD  1 
ATOM   13350 C CE  . LYS D 1 317 ? -15.439 98.663  16.461 1.00 101.01 ? 325 LYS D CE  1 
ATOM   13351 N NZ  . LYS D 1 317 ? -16.506 98.799  17.464 1.00 56.36  ? 325 LYS D NZ  1 
ATOM   13352 N N   . VAL D 1 318 ? -9.082  95.691  15.252 1.00 102.41 ? 326 VAL D N   1 
ATOM   13353 C CA  . VAL D 1 318 ? -8.212  95.276  14.164 1.00 97.44  ? 326 VAL D CA  1 
ATOM   13354 C C   . VAL D 1 318 ? -7.868  93.788  14.281 1.00 98.12  ? 326 VAL D C   1 
ATOM   13355 O O   . VAL D 1 318 ? -8.044  93.022  13.329 1.00 93.80  ? 326 VAL D O   1 
ATOM   13356 C CB  . VAL D 1 318 ? -6.958  96.161  14.257 1.00 90.63  ? 326 VAL D CB  1 
ATOM   13357 C CG1 . VAL D 1 318 ? -5.758  95.496  13.593 1.00 108.65 ? 326 VAL D CG1 1 
ATOM   13358 C CG2 . VAL D 1 318 ? -7.223  97.547  13.674 1.00 73.20  ? 326 VAL D CG2 1 
ATOM   13359 N N   . TYR D 1 319 ? -7.396  93.402  15.471 1.00 92.93  ? 327 TYR D N   1 
ATOM   13360 C CA  . TYR D 1 319 ? -7.095  92.018  15.824 1.00 81.49  ? 327 TYR D CA  1 
ATOM   13361 C C   . TYR D 1 319 ? -8.231  91.089  15.380 1.00 71.41  ? 327 TYR D C   1 
ATOM   13362 O O   . TYR D 1 319 ? -8.009  90.107  14.693 1.00 61.60  ? 327 TYR D O   1 
ATOM   13363 C CB  . TYR D 1 319 ? -6.812  91.861  17.331 1.00 80.93  ? 327 TYR D CB  1 
ATOM   13364 C CG  . TYR D 1 319 ? -6.892  90.419  17.814 1.00 89.03  ? 327 TYR D CG  1 
ATOM   13365 C CD1 . TYR D 1 319 ? -5.933  89.482  17.450 1.00 91.67  ? 327 TYR D CD1 1 
ATOM   13366 C CD2 . TYR D 1 319 ? -7.910  89.986  18.646 1.00 89.59  ? 327 TYR D CD2 1 
ATOM   13367 C CE1 . TYR D 1 319 ? -5.997  88.166  17.877 1.00 94.12  ? 327 TYR D CE1 1 
ATOM   13368 C CE2 . TYR D 1 319 ? -7.975  88.672  19.084 1.00 99.42  ? 327 TYR D CE2 1 
ATOM   13369 C CZ  . TYR D 1 319 ? -7.037  87.748  18.683 1.00 106.28 ? 327 TYR D CZ  1 
ATOM   13370 O OH  . TYR D 1 319 ? -7.152  86.459  19.115 1.00 105.56 ? 327 TYR D OH  1 
ATOM   13371 N N   . GLN D 1 320 ? -9.465  91.403  15.760 1.00 71.08  ? 328 GLN D N   1 
ATOM   13372 C CA  . GLN D 1 320 ? -10.608 90.584  15.385 1.00 74.51  ? 328 GLN D CA  1 
ATOM   13373 C C   . GLN D 1 320 ? -10.768 90.518  13.865 1.00 84.45  ? 328 GLN D C   1 
ATOM   13374 O O   . GLN D 1 320 ? -11.044 89.444  13.298 1.00 89.95  ? 328 GLN D O   1 
ATOM   13375 C CB  . GLN D 1 320 ? -11.882 90.990  16.131 1.00 60.18  ? 328 GLN D CB  1 
ATOM   13376 C CG  . GLN D 1 320 ? -11.773 90.800  17.647 1.00 68.45  ? 328 GLN D CG  1 
ATOM   13377 C CD  . GLN D 1 320 ? -11.529 89.378  18.112 1.00 82.83  ? 328 GLN D CD  1 
ATOM   13378 O OE1 . GLN D 1 320 ? -11.620 88.399  17.370 1.00 128.38 ? 328 GLN D OE1 1 
ATOM   13379 N NE2 . GLN D 1 320 ? -11.229 89.229  19.381 1.00 74.66  ? 328 GLN D NE2 1 
ATOM   13380 N N   . HIS D 1 321 ? -10.605 91.668  13.193 1.00 84.65  ? 329 HIS D N   1 
ATOM   13381 C CA  . HIS D 1 321 ? -10.747 91.640  11.744 1.00 84.87  ? 329 HIS D CA  1 
ATOM   13382 C C   . HIS D 1 321 ? -9.688  90.690  11.202 1.00 72.67  ? 329 HIS D C   1 
ATOM   13383 O O   . HIS D 1 321 ? -9.997  89.809  10.397 1.00 94.90  ? 329 HIS D O   1 
ATOM   13384 C CB  . HIS D 1 321 ? -10.818 93.024  11.083 1.00 83.03  ? 329 HIS D CB  1 
ATOM   13385 C CG  . HIS D 1 321 ? -12.129 93.748  11.212 1.00 89.52  ? 329 HIS D CG  1 
ATOM   13386 N ND1 . HIS D 1 321 ? -13.129 93.628  10.267 1.00 112.69 ? 329 HIS D ND1 1 
ATOM   13387 C CD2 . HIS D 1 321 ? -12.621 94.610  12.147 1.00 95.22  ? 329 HIS D CD2 1 
ATOM   13388 C CE1 . HIS D 1 321 ? -14.179 94.389  10.604 1.00 94.30  ? 329 HIS D CE1 1 
ATOM   13389 N NE2 . HIS D 1 321 ? -13.890 94.989  11.746 1.00 88.91  ? 329 HIS D NE2 1 
ATOM   13390 N N   . GLN D 1 322 ? -8.462  90.833  11.710 1.00 62.55  ? 330 GLN D N   1 
ATOM   13391 C CA  . GLN D 1 322 ? -7.364  89.977  11.299 1.00 72.04  ? 330 GLN D CA  1 
ATOM   13392 C C   . GLN D 1 322 ? -7.683  88.512  11.595 1.00 86.47  ? 330 GLN D C   1 
ATOM   13393 O O   . GLN D 1 322 ? -7.450  87.649  10.751 1.00 97.68  ? 330 GLN D O   1 
ATOM   13394 C CB  . GLN D 1 322 ? -6.084  90.360  12.038 1.00 78.51  ? 330 GLN D CB  1 
ATOM   13395 C CG  . GLN D 1 322 ? -4.844  89.703  11.456 1.00 74.72  ? 330 GLN D CG  1 
ATOM   13396 C CD  . GLN D 1 322 ? -4.652  90.065  9.990  1.00 86.97  ? 330 GLN D CD  1 
ATOM   13397 O OE1 . GLN D 1 322 ? -4.715  91.251  9.640  1.00 100.73 ? 330 GLN D OE1 1 
ATOM   13398 N NE2 . GLN D 1 322 ? -4.408  89.072  9.127  1.00 75.09  ? 330 GLN D NE2 1 
ATOM   13399 N N   . VAL D 1 323 ? -8.249  88.239  12.778 1.00 75.87  ? 331 VAL D N   1 
ATOM   13400 C CA  . VAL D 1 323 ? -8.562  86.870  13.157 1.00 68.42  ? 331 VAL D CA  1 
ATOM   13401 C C   . VAL D 1 323 ? -9.409  86.242  12.053 1.00 79.39  ? 331 VAL D C   1 
ATOM   13402 O O   . VAL D 1 323 ? -9.146  85.110  11.623 1.00 77.30  ? 331 VAL D O   1 
ATOM   13403 C CB  . VAL D 1 323 ? -9.320  86.816  14.493 1.00 63.74  ? 331 VAL D CB  1 
ATOM   13404 C CG1 . VAL D 1 323 ? -10.219 85.596  14.516 1.00 73.81  ? 331 VAL D CG1 1 
ATOM   13405 C CG2 . VAL D 1 323 ? -8.408  86.872  15.725 1.00 87.34  ? 331 VAL D CG2 1 
ATOM   13406 N N   . VAL D 1 324 ? -10.415 87.006  11.584 1.00 60.67  ? 332 VAL D N   1 
ATOM   13407 C CA  . VAL D 1 324 ? -11.288 86.437  10.575 1.00 70.25  ? 332 VAL D CA  1 
ATOM   13408 C C   . VAL D 1 324 ? -10.595 86.328  9.205  1.00 72.58  ? 332 VAL D C   1 
ATOM   13409 O O   . VAL D 1 324 ? -10.861 85.397  8.416  1.00 57.12  ? 332 VAL D O   1 
ATOM   13410 C CB  . VAL D 1 324 ? -12.672 87.082  10.456 1.00 62.38  ? 332 VAL D CB  1 
ATOM   13411 C CG1 . VAL D 1 324 ? -13.442 86.402  9.322  1.00 64.25  ? 332 VAL D CG1 1 
ATOM   13412 C CG2 . VAL D 1 324 ? -13.467 87.001  11.750 1.00 53.03  ? 332 VAL D CG2 1 
ATOM   13413 N N   . ALA D 1 325 ? -9.744  87.316  8.914  1.00 73.80  ? 333 ALA D N   1 
ATOM   13414 C CA  . ALA D 1 325 ? -8.968  87.308  7.688  1.00 89.78  ? 333 ALA D CA  1 
ATOM   13415 C C   . ALA D 1 325 ? -8.116  86.040  7.625  1.00 104.10 ? 333 ALA D C   1 
ATOM   13416 O O   . ALA D 1 325 ? -8.121  85.314  6.618  1.00 119.39 ? 333 ALA D O   1 
ATOM   13417 C CB  . ALA D 1 325 ? -8.101  88.533  7.648  1.00 81.80  ? 333 ALA D CB  1 
ATOM   13418 N N   . ASN D 1 326 ? -7.426  85.787  8.739  1.00 78.99  ? 334 ASN D N   1 
ATOM   13419 C CA  . ASN D 1 326 ? -6.524  84.662  8.870  1.00 87.69  ? 334 ASN D CA  1 
ATOM   13420 C C   . ASN D 1 326 ? -7.288  83.364  8.622  1.00 98.36  ? 334 ASN D C   1 
ATOM   13421 O O   . ASN D 1 326 ? -6.849  82.492  7.876  1.00 117.08 ? 334 ASN D O   1 
ATOM   13422 C CB  . ASN D 1 326 ? -5.830  84.698  10.233 1.00 97.48  ? 334 ASN D CB  1 
ATOM   13423 C CG  . ASN D 1 326 ? -4.780  85.776  10.342 1.00 100.44 ? 334 ASN D CG  1 
ATOM   13424 O OD1 . ASN D 1 326 ? -4.304  86.296  9.315  1.00 96.26  ? 334 ASN D OD1 1 
ATOM   13425 N ND2 . ASN D 1 326 ? -4.418  86.139  11.566 1.00 76.38  ? 334 ASN D ND2 1 
ATOM   13426 N N   . CYS D 1 327 ? -8.445  83.243  9.269  1.00 92.59  ? 335 CYS D N   1 
ATOM   13427 C CA  . CYS D 1 327 ? -9.258  82.056  9.102  1.00 84.73  ? 335 CYS D CA  1 
ATOM   13428 C C   . CYS D 1 327 ? -9.598  81.845  7.618  1.00 73.74  ? 335 CYS D C   1 
ATOM   13429 O O   . CYS D 1 327 ? -9.492  80.726  7.101  1.00 57.95  ? 335 CYS D O   1 
ATOM   13430 C CB  . CYS D 1 327 ? -10.497 82.183  9.972  1.00 84.48  ? 335 CYS D CB  1 
ATOM   13431 S SG  . CYS D 1 327 ? -11.529 80.712  9.811  1.00 101.59 ? 335 CYS D SG  1 
ATOM   13432 N N   . ARG D 1 328 ? -9.976  82.933  6.930  1.00 65.30  ? 336 ARG D N   1 
ATOM   13433 C CA  . ARG D 1 328 ? -10.339 82.818  5.526  1.00 78.34  ? 336 ARG D CA  1 
ATOM   13434 C C   . ARG D 1 328 ? -9.132  82.327  4.735  1.00 80.90  ? 336 ARG D C   1 
ATOM   13435 O O   . ARG D 1 328 ? -9.277  81.379  3.939  1.00 54.40  ? 336 ARG D O   1 
ATOM   13436 C CB  . ARG D 1 328 ? -11.024 84.036  4.910  1.00 75.06  ? 336 ARG D CB  1 
ATOM   13437 C CG  . ARG D 1 328 ? -12.380 84.257  5.577  1.00 83.07  ? 336 ARG D CG  1 
ATOM   13438 C CD  . ARG D 1 328 ? -13.558 84.770  4.767  1.00 76.82  ? 336 ARG D CD  1 
ATOM   13439 N NE  . ARG D 1 328 ? -14.204 85.855  5.524  1.00 92.36  ? 336 ARG D NE  1 
ATOM   13440 C CZ  . ARG D 1 328 ? -15.424 85.893  6.101  1.00 79.62  ? 336 ARG D CZ  1 
ATOM   13441 N NH1 . ARG D 1 328 ? -16.089 84.803  6.377  1.00 57.12  ? 336 ARG D NH1 1 
ATOM   13442 N NH2 . ARG D 1 328 ? -16.023 87.029  6.418  1.00 85.60  ? 336 ARG D NH2 1 
ATOM   13443 N N   . ALA D 1 329 ? -7.965  82.945  5.019  1.00 74.95  ? 337 ALA D N   1 
ATOM   13444 C CA  . ALA D 1 329 ? -6.717  82.601  4.334  1.00 94.61  ? 337 ALA D CA  1 
ATOM   13445 C C   . ALA D 1 329 ? -6.417  81.107  4.459  1.00 89.39  ? 337 ALA D C   1 
ATOM   13446 O O   . ALA D 1 329 ? -6.209  80.404  3.450  1.00 68.77  ? 337 ALA D O   1 
ATOM   13447 C CB  . ALA D 1 329 ? -5.560  83.430  4.851  1.00 71.45  ? 337 ALA D CB  1 
ATOM   13448 N N   . LEU D 1 330 ? -6.408  80.670  5.726  1.00 75.97  ? 338 LEU D N   1 
ATOM   13449 C CA  . LEU D 1 330 ? -6.196  79.267  6.063  1.00 70.36  ? 338 LEU D CA  1 
ATOM   13450 C C   . LEU D 1 330 ? -7.208  78.361  5.345  1.00 70.31  ? 338 LEU D C   1 
ATOM   13451 O O   . LEU D 1 330 ? -6.805  77.365  4.733  1.00 73.25  ? 338 LEU D O   1 
ATOM   13452 C CB  . LEU D 1 330 ? -6.245  79.097  7.573  1.00 63.14  ? 338 LEU D CB  1 
ATOM   13453 C CG  . LEU D 1 330 ? -6.133  77.657  8.071  1.00 52.63  ? 338 LEU D CG  1 
ATOM   13454 C CD1 . LEU D 1 330 ? -4.810  77.058  7.638  1.00 55.53  ? 338 LEU D CD1 1 
ATOM   13455 C CD2 . LEU D 1 330 ? -6.282  77.594  9.610  1.00 46.41  ? 338 LEU D CD2 1 
ATOM   13456 N N   . SER D 1 331 ? -8.503  78.727  5.391  1.00 55.72  ? 339 SER D N   1 
ATOM   13457 C CA  . SER D 1 331 ? -9.530  77.937  4.728  1.00 56.54  ? 339 SER D CA  1 
ATOM   13458 C C   . SER D 1 331 ? -9.237  77.842  3.223  1.00 65.26  ? 339 SER D C   1 
ATOM   13459 O O   . SER D 1 331 ? -9.195  76.758  2.616  1.00 45.35  ? 339 SER D O   1 
ATOM   13460 C CB  . SER D 1 331 ? -10.865 78.543  4.926  1.00 62.34  ? 339 SER D CB  1 
ATOM   13461 O OG  . SER D 1 331 ? -11.875 77.788  4.262  1.00 66.83  ? 339 SER D OG  1 
ATOM   13462 N N   . GLU D 1 332 ? -9.007  79.012  2.606  1.00 62.95  ? 340 GLU D N   1 
ATOM   13463 C CA  . GLU D 1 332 ? -8.818  79.030  1.168  1.00 74.69  ? 340 GLU D CA  1 
ATOM   13464 C C   . GLU D 1 332 ? -7.638  78.100  0.825  1.00 84.49  ? 340 GLU D C   1 
ATOM   13465 O O   . GLU D 1 332 ? -7.743  77.255  -0.076 1.00 67.27  ? 340 GLU D O   1 
ATOM   13466 C CB  . GLU D 1 332 ? -8.744  80.513  0.788  1.00 79.77  ? 340 GLU D CB  1 
ATOM   13467 C CG  . GLU D 1 332 ? -8.467  80.770  -0.687 1.00 104.57 ? 340 GLU D CG  1 
ATOM   13468 C CD  . GLU D 1 332 ? -8.056  82.198  -1.013 1.00 121.96 ? 340 GLU D CD  1 
ATOM   13469 O OE1 . GLU D 1 332 ? -8.443  83.116  -0.241 1.00 144.80 ? 340 GLU D OE1 1 
ATOM   13470 O OE2 . GLU D 1 332 ? -7.315  82.378  -2.012 1.00 114.87 ? 340 GLU D OE2 1 
ATOM   13471 N N   . ALA D 1 333 ? -6.526  78.260  1.575  1.00 87.10  ? 341 ALA D N   1 
ATOM   13472 C CA  . ALA D 1 333 ? -5.291  77.532  1.322  1.00 73.59  ? 341 ALA D CA  1 
ATOM   13473 C C   . ALA D 1 333 ? -5.526  76.019  1.356  1.00 93.38  ? 341 ALA D C   1 
ATOM   13474 O O   . ALA D 1 333 ? -5.119  75.288  0.445  1.00 120.40 ? 341 ALA D O   1 
ATOM   13475 C CB  . ALA D 1 333 ? -4.232  77.957  2.318  1.00 61.95  ? 341 ALA D CB  1 
ATOM   13476 N N   . LEU D 1 334 ? -6.202  75.550  2.412  1.00 87.01  ? 342 LEU D N   1 
ATOM   13477 C CA  . LEU D 1 334 ? -6.439  74.123  2.537  1.00 101.63 ? 342 LEU D CA  1 
ATOM   13478 C C   . LEU D 1 334 ? -7.338  73.638  1.395  1.00 96.08  ? 342 LEU D C   1 
ATOM   13479 O O   . LEU D 1 334 ? -7.170  72.536  0.857  1.00 79.79  ? 342 LEU D O   1 
ATOM   13480 C CB  . LEU D 1 334 ? -7.037  73.801  3.905  1.00 84.85  ? 342 LEU D CB  1 
ATOM   13481 C CG  . LEU D 1 334 ? -6.103  74.097  5.063  1.00 96.11  ? 342 LEU D CG  1 
ATOM   13482 C CD1 . LEU D 1 334 ? -6.911  74.082  6.341  1.00 148.96 ? 342 LEU D CD1 1 
ATOM   13483 C CD2 . LEU D 1 334 ? -5.033  73.047  5.049  1.00 89.82  ? 342 LEU D CD2 1 
ATOM   13484 N N   . THR D 1 335 ? -8.304  74.490  1.034  1.00 78.31  ? 343 THR D N   1 
ATOM   13485 C CA  . THR D 1 335 ? -9.274  74.082  0.037  1.00 90.21  ? 343 THR D CA  1 
ATOM   13486 C C   . THR D 1 335 ? -8.554  73.901  -1.283 1.00 100.73 ? 343 THR D C   1 
ATOM   13487 O O   . THR D 1 335 ? -8.864  72.936  -1.981 1.00 72.73  ? 343 THR D O   1 
ATOM   13488 C CB  . THR D 1 335 ? -10.433 75.052  -0.146 1.00 79.22  ? 343 THR D CB  1 
ATOM   13489 O OG1 . THR D 1 335 ? -11.024 75.165  1.146  1.00 97.07  ? 343 THR D OG1 1 
ATOM   13490 C CG2 . THR D 1 335 ? -11.365 74.589  -1.254 1.00 48.36  ? 343 THR D CG2 1 
ATOM   13491 N N   . GLU D 1 336 ? -7.649  74.851  -1.596 1.00 108.90 ? 344 GLU D N   1 
ATOM   13492 C CA  . GLU D 1 336 ? -6.829  74.801  -2.794 1.00 98.38  ? 344 GLU D CA  1 
ATOM   13493 C C   . GLU D 1 336 ? -6.009  73.515  -2.797 1.00 106.42 ? 344 GLU D C   1 
ATOM   13494 O O   . GLU D 1 336 ? -5.888  72.862  -3.846 1.00 110.78 ? 344 GLU D O   1 
ATOM   13495 C CB  . GLU D 1 336 ? -5.929  76.029  -2.862 1.00 100.35 ? 344 GLU D CB  1 
ATOM   13496 C CG  . GLU D 1 336 ? -6.681  77.337  -3.080 1.00 104.00 ? 344 GLU D CG  1 
ATOM   13497 C CD  . GLU D 1 336 ? -5.682  78.448  -3.330 1.00 102.23 ? 344 GLU D CD  1 
ATOM   13498 O OE1 . GLU D 1 336 ? -4.555  78.427  -2.744 1.00 79.22  ? 344 GLU D OE1 1 
ATOM   13499 O OE2 . GLU D 1 336 ? -6.056  79.344  -4.129 1.00 95.06  ? 344 GLU D OE2 1 
ATOM   13500 N N   . LEU D 1 337 ? -5.482  73.160  -1.607 1.00 87.28  ? 345 LEU D N   1 
ATOM   13501 C CA  . LEU D 1 337 ? -4.695  71.943  -1.426 1.00 85.41  ? 345 LEU D CA  1 
ATOM   13502 C C   . LEU D 1 337 ? -5.577  70.685  -1.447 1.00 105.81 ? 345 LEU D C   1 
ATOM   13503 O O   . LEU D 1 337 ? -5.092  69.591  -1.152 1.00 120.41 ? 345 LEU D O   1 
ATOM   13504 C CB  . LEU D 1 337 ? -3.946  72.035  -0.103 1.00 70.12  ? 345 LEU D CB  1 
ATOM   13505 C CG  . LEU D 1 337 ? -2.674  72.881  -0.129 1.00 81.33  ? 345 LEU D CG  1 
ATOM   13506 C CD1 . LEU D 1 337 ? -2.322  73.337  1.275  1.00 108.40 ? 345 LEU D CD1 1 
ATOM   13507 C CD2 . LEU D 1 337 ? -1.532  72.108  -0.727 1.00 85.52  ? 345 LEU D CD2 1 
ATOM   13508 N N   . GLY D 1 338 ? -6.877  70.852  -1.743 1.00 87.56  ? 346 GLY D N   1 
ATOM   13509 C CA  . GLY D 1 338 ? -7.805  69.750  -1.914 1.00 69.72  ? 346 GLY D CA  1 
ATOM   13510 C C   . GLY D 1 338 ? -8.503  69.267  -0.635 1.00 89.58  ? 346 GLY D C   1 
ATOM   13511 O O   . GLY D 1 338 ? -9.264  68.297  -0.724 1.00 91.12  ? 346 GLY D O   1 
ATOM   13512 N N   . TYR D 1 339 ? -8.313  69.951  0.510  1.00 75.52  ? 347 TYR D N   1 
ATOM   13513 C CA  . TYR D 1 339 ? -9.000  69.553  1.736  1.00 63.65  ? 347 TYR D CA  1 
ATOM   13514 C C   . TYR D 1 339 ? -10.461 70.019  1.728  1.00 81.64  ? 347 TYR D C   1 
ATOM   13515 O O   . TYR D 1 339 ? -10.755 71.094  1.199  1.00 98.56  ? 347 TYR D O   1 
ATOM   13516 C CB  . TYR D 1 339 ? -8.316  70.215  2.931  1.00 64.50  ? 347 TYR D CB  1 
ATOM   13517 C CG  . TYR D 1 339 ? -6.950  69.666  3.309  1.00 70.89  ? 347 TYR D CG  1 
ATOM   13518 C CD1 . TYR D 1 339 ? -6.847  68.504  4.055  1.00 96.30  ? 347 TYR D CD1 1 
ATOM   13519 C CD2 . TYR D 1 339 ? -5.777  70.253  2.869  1.00 74.44  ? 347 TYR D CD2 1 
ATOM   13520 C CE1 . TYR D 1 339 ? -5.621  67.953  4.376  1.00 96.10  ? 347 TYR D CE1 1 
ATOM   13521 C CE2 . TYR D 1 339 ? -4.536  69.745  3.216  1.00 87.66  ? 347 TYR D CE2 1 
ATOM   13522 C CZ  . TYR D 1 339 ? -4.460  68.574  3.955  1.00 105.20 ? 347 TYR D CZ  1 
ATOM   13523 O OH  . TYR D 1 339 ? -3.294  67.986  4.357  1.00 97.67  ? 347 TYR D OH  1 
ATOM   13524 N N   . LYS D 1 340 ? -11.378 69.209  2.300  1.00 58.37  ? 348 LYS D N   1 
ATOM   13525 C CA  . LYS D 1 340 ? -12.788 69.603  2.382  1.00 75.48  ? 348 LYS D CA  1 
ATOM   13526 C C   . LYS D 1 340 ? -13.047 70.466  3.620  1.00 96.58  ? 348 LYS D C   1 
ATOM   13527 O O   . LYS D 1 340 ? -12.727 70.039  4.735  1.00 97.13  ? 348 LYS D O   1 
ATOM   13528 C CB  . LYS D 1 340 ? -13.705 68.388  2.471  1.00 69.67  ? 348 LYS D CB  1 
ATOM   13529 C CG  . LYS D 1 340 ? -15.182 68.770  2.314  1.00 64.90  ? 348 LYS D CG  1 
ATOM   13530 C CD  . LYS D 1 340 ? -16.156 67.592  2.451  1.00 78.78  ? 348 LYS D CD  1 
ATOM   13531 C CE  . LYS D 1 340 ? -15.819 66.146  1.987  1.00 111.57 ? 348 LYS D CE  1 
ATOM   13532 N NZ  . LYS D 1 340 ? -15.038 65.830  0.761  1.00 69.16  ? 348 LYS D NZ  1 
ATOM   13533 N N   . ILE D 1 341 ? -13.603 71.674  3.427  1.00 77.14  ? 349 ILE D N   1 
ATOM   13534 C CA  . ILE D 1 341 ? -13.907 72.525  4.571  1.00 64.14  ? 349 ILE D CA  1 
ATOM   13535 C C   . ILE D 1 341 ? -15.415 72.459  4.789  1.00 62.50  ? 349 ILE D C   1 
ATOM   13536 O O   . ILE D 1 341 ? -16.155 72.873  3.914  1.00 51.03  ? 349 ILE D O   1 
ATOM   13537 C CB  . ILE D 1 341 ? -13.423 73.980  4.335  1.00 56.60  ? 349 ILE D CB  1 
ATOM   13538 C CG1 . ILE D 1 341 ? -11.916 74.063  4.254  1.00 51.75  ? 349 ILE D CG1 1 
ATOM   13539 C CG2 . ILE D 1 341 ? -13.862 74.902  5.463  1.00 54.90  ? 349 ILE D CG2 1 
ATOM   13540 C CD1 . ILE D 1 341 ? -11.177 73.491  5.445  1.00 40.53  ? 349 ILE D CD1 1 
ATOM   13541 N N   . VAL D 1 342 ? -15.860 71.973  5.955  1.00 74.76  ? 350 VAL D N   1 
ATOM   13542 C CA  . VAL D 1 342 ? -17.282 71.840  6.244  1.00 78.19  ? 350 VAL D CA  1 
ATOM   13543 C C   . VAL D 1 342 ? -17.932 73.203  6.082  1.00 78.46  ? 350 VAL D C   1 
ATOM   13544 O O   . VAL D 1 342 ? -17.431 74.214  6.588  1.00 61.03  ? 350 VAL D O   1 
ATOM   13545 C CB  . VAL D 1 342 ? -17.607 71.295  7.647  1.00 89.34  ? 350 VAL D CB  1 
ATOM   13546 C CG1 . VAL D 1 342 ? -19.115 71.311  7.895  1.00 88.64  ? 350 VAL D CG1 1 
ATOM   13547 C CG2 . VAL D 1 342 ? -17.050 69.886  7.858  1.00 82.49  ? 350 VAL D CG2 1 
ATOM   13548 N N   . THR D 1 343 ? -19.075 73.175  5.390  1.00 76.21  ? 351 THR D N   1 
ATOM   13549 C CA  . THR D 1 343 ? -19.836 74.382  5.091  1.00 73.93  ? 351 THR D CA  1 
ATOM   13550 C C   . THR D 1 343 ? -19.183 75.197  3.969  1.00 86.51  ? 351 THR D C   1 
ATOM   13551 O O   . THR D 1 343 ? -19.761 76.201  3.536  1.00 94.78  ? 351 THR D O   1 
ATOM   13552 C CB  . THR D 1 343 ? -20.047 75.260  6.316  1.00 61.49  ? 351 THR D CB  1 
ATOM   13553 O OG1 . THR D 1 343 ? -21.188 76.012  5.903  1.00 59.43  ? 351 THR D OG1 1 
ATOM   13554 C CG2 . THR D 1 343 ? -18.819 76.093  6.687  1.00 45.26  ? 351 THR D CG2 1 
ATOM   13555 N N   . GLY D 1 344 ? -17.993 74.791  3.502  1.00 78.54  ? 352 GLY D N   1 
ATOM   13556 C CA  . GLY D 1 344 ? -17.400 75.481  2.373  1.00 62.32  ? 352 GLY D CA  1 
ATOM   13557 C C   . GLY D 1 344 ? -16.338 76.466  2.852  1.00 71.64  ? 352 GLY D C   1 
ATOM   13558 O O   . GLY D 1 344 ? -15.450 76.858  2.123  1.00 81.75  ? 352 GLY D O   1 
ATOM   13559 N N   . GLY D 1 345 ? -16.407 76.871  4.111  1.00 71.74  ? 353 GLY D N   1 
ATOM   13560 C CA  . GLY D 1 345 ? -15.529 77.949  4.529  1.00 73.33  ? 353 GLY D CA  1 
ATOM   13561 C C   . GLY D 1 345 ? -15.951 78.463  5.901  1.00 88.38  ? 353 GLY D C   1 
ATOM   13562 O O   . GLY D 1 345 ? -16.531 77.723  6.693  1.00 113.78 ? 353 GLY D O   1 
ATOM   13563 N N   . SER D 1 346 ? -15.705 79.752  6.136  1.00 76.89  ? 354 SER D N   1 
ATOM   13564 C CA  . SER D 1 346 ? -15.874 80.332  7.452  1.00 81.03  ? 354 SER D CA  1 
ATOM   13565 C C   . SER D 1 346 ? -16.264 81.809  7.385  1.00 74.38  ? 354 SER D C   1 
ATOM   13566 O O   . SER D 1 346 ? -15.765 82.564  6.571  1.00 80.07  ? 354 SER D O   1 
ATOM   13567 C CB  . SER D 1 346 ? -14.646 80.119  8.313  1.00 68.36  ? 354 SER D CB  1 
ATOM   13568 O OG  . SER D 1 346 ? -14.919 80.600  9.624  1.00 82.64  ? 354 SER D OG  1 
ATOM   13569 N N   . ASP D 1 347 ? -17.159 82.203  8.288  1.00 83.45  ? 355 ASP D N   1 
ATOM   13570 C CA  . ASP D 1 347 ? -17.509 83.588  8.538  1.00 79.42  ? 355 ASP D CA  1 
ATOM   13571 C C   . ASP D 1 347 ? -16.785 84.073  9.794  1.00 99.22  ? 355 ASP D C   1 
ATOM   13572 O O   . ASP D 1 347 ? -16.900 85.255  10.109 1.00 102.89 ? 355 ASP D O   1 
ATOM   13573 C CB  . ASP D 1 347 ? -19.006 83.733  8.731  1.00 81.61  ? 355 ASP D CB  1 
ATOM   13574 C CG  . ASP D 1 347 ? -19.854 83.168  7.600  1.00 96.48  ? 355 ASP D CG  1 
ATOM   13575 O OD1 . ASP D 1 347 ? -19.372 83.271  6.457  1.00 77.55  ? 355 ASP D OD1 1 
ATOM   13576 O OD2 . ASP D 1 347 ? -20.993 82.658  7.865  1.00 116.79 ? 355 ASP D OD2 1 
ATOM   13577 N N   . ASN D 1 348 ? -16.043 83.178  10.484 1.00 88.52  ? 356 ASN D N   1 
ATOM   13578 C CA  . ASN D 1 348 ? -15.538 83.445  11.832 1.00 95.75  ? 356 ASN D CA  1 
ATOM   13579 C C   . ASN D 1 348 ? -14.085 82.996  11.982 1.00 100.40 ? 356 ASN D C   1 
ATOM   13580 O O   . ASN D 1 348 ? -13.327 82.991  11.024 1.00 108.49 ? 356 ASN D O   1 
ATOM   13581 C CB  . ASN D 1 348 ? -16.419 82.851  12.944 1.00 88.94  ? 356 ASN D CB  1 
ATOM   13582 C CG  . ASN D 1 348 ? -16.721 81.371  12.749 1.00 93.80  ? 356 ASN D CG  1 
ATOM   13583 O OD1 . ASN D 1 348 ? -15.821 80.559  12.548 1.00 106.04 ? 356 ASN D OD1 1 
ATOM   13584 N ND2 . ASN D 1 348 ? -17.970 80.945  12.753 1.00 66.46  ? 356 ASN D ND2 1 
ATOM   13585 N N   . HIS D 1 349 ? -13.727 82.580  13.203 1.00 88.98  ? 357 HIS D N   1 
ATOM   13586 C CA  . HIS D 1 349 ? -12.347 82.310  13.578 1.00 100.34 ? 357 HIS D CA  1 
ATOM   13587 C C   . HIS D 1 349 ? -11.956 80.829  13.415 1.00 96.33  ? 357 HIS D C   1 
ATOM   13588 O O   . HIS D 1 349 ? -10.794 80.457  13.661 1.00 81.10  ? 357 HIS D O   1 
ATOM   13589 C CB  . HIS D 1 349 ? -12.144 82.711  15.043 1.00 81.79  ? 357 HIS D CB  1 
ATOM   13590 C CG  . HIS D 1 349 ? -13.052 81.947  15.935 1.00 98.31  ? 357 HIS D CG  1 
ATOM   13591 N ND1 . HIS D 1 349 ? -14.425 81.865  15.764 1.00 102.77 ? 357 HIS D ND1 1 
ATOM   13592 C CD2 . HIS D 1 349 ? -12.741 81.131  16.959 1.00 116.96 ? 357 HIS D CD2 1 
ATOM   13593 C CE1 . HIS D 1 349 ? -14.910 81.053  16.714 1.00 117.03 ? 357 HIS D CE1 1 
ATOM   13594 N NE2 . HIS D 1 349 ? -13.902 80.606  17.453 1.00 112.93 ? 357 HIS D NE2 1 
ATOM   13595 N N   . LEU D 1 350 ? -12.909 79.963  13.038 1.00 58.63  ? 358 LEU D N   1 
ATOM   13596 C CA  . LEU D 1 350 ? -12.583 78.540  12.955 1.00 66.43  ? 358 LEU D CA  1 
ATOM   13597 C C   . LEU D 1 350 ? -13.132 77.928  11.665 1.00 82.47  ? 358 LEU D C   1 
ATOM   13598 O O   . LEU D 1 350 ? -14.108 78.423  11.070 1.00 77.24  ? 358 LEU D O   1 
ATOM   13599 C CB  . LEU D 1 350 ? -12.988 77.695  14.170 1.00 58.57  ? 358 LEU D CB  1 
ATOM   13600 C CG  . LEU D 1 350 ? -14.490 77.595  14.454 1.00 82.20  ? 358 LEU D CG  1 
ATOM   13601 C CD1 . LEU D 1 350 ? -15.279 76.618  13.595 1.00 77.27  ? 358 LEU D CD1 1 
ATOM   13602 C CD2 . LEU D 1 350 ? -14.742 77.302  15.926 1.00 104.00 ? 358 LEU D CD2 1 
ATOM   13603 N N   . ILE D 1 351 ? -12.511 76.798  11.291 1.00 86.73  ? 359 ILE D N   1 
ATOM   13604 C CA  . ILE D 1 351 ? -12.998 75.940  10.219 1.00 77.83  ? 359 ILE D CA  1 
ATOM   13605 C C   . ILE D 1 351 ? -13.004 74.507  10.713 1.00 83.01  ? 359 ILE D C   1 
ATOM   13606 O O   . ILE D 1 351 ? -12.231 74.132  11.624 1.00 78.94  ? 359 ILE D O   1 
ATOM   13607 C CB  . ILE D 1 351 ? -12.094 76.039  8.985  1.00 79.66  ? 359 ILE D CB  1 
ATOM   13608 C CG1 . ILE D 1 351 ? -10.593 75.873  9.396  1.00 61.25  ? 359 ILE D CG1 1 
ATOM   13609 C CG2 . ILE D 1 351 ? -12.382 77.321  8.196  1.00 62.78  ? 359 ILE D CG2 1 
ATOM   13610 C CD1 . ILE D 1 351 ? -9.638  75.956  8.234  1.00 70.13  ? 359 ILE D CD1 1 
ATOM   13611 N N   . LEU D 1 352 ? -13.900 73.732  10.091 1.00 73.76  ? 360 LEU D N   1 
ATOM   13612 C CA  . LEU D 1 352 ? -13.873 72.312  10.398 1.00 95.54  ? 360 LEU D CA  1 
ATOM   13613 C C   . LEU D 1 352 ? -13.389 71.582  9.159  1.00 105.91 ? 360 LEU D C   1 
ATOM   13614 O O   . LEU D 1 352 ? -14.058 71.633  8.124  1.00 109.96 ? 360 LEU D O   1 
ATOM   13615 C CB  . LEU D 1 352 ? -15.243 71.811  10.840 1.00 97.76  ? 360 LEU D CB  1 
ATOM   13616 C CG  . LEU D 1 352 ? -15.350 70.324  11.178 1.00 87.89  ? 360 LEU D CG  1 
ATOM   13617 C CD1 . LEU D 1 352 ? -14.376 70.013  12.259 1.00 80.37  ? 360 LEU D CD1 1 
ATOM   13618 C CD2 . LEU D 1 352 ? -16.747 69.996  11.643 1.00 81.82  ? 360 LEU D CD2 1 
ATOM   13619 N N   . VAL D 1 353 ? -12.213 70.960  9.266  1.00 85.15  ? 361 VAL D N   1 
ATOM   13620 C CA  . VAL D 1 353 ? -11.627 70.331  8.092  1.00 79.63  ? 361 VAL D CA  1 
ATOM   13621 C C   . VAL D 1 353 ? -11.977 68.846  8.095  1.00 70.94  ? 361 VAL D C   1 
ATOM   13622 O O   . VAL D 1 353 ? -11.463 68.098  8.941  1.00 56.68  ? 361 VAL D O   1 
ATOM   13623 C CB  . VAL D 1 353 ? -10.097 70.437  8.014  1.00 70.50  ? 361 VAL D CB  1 
ATOM   13624 C CG1 . VAL D 1 353 ? -9.621  69.757  6.738  1.00 63.45  ? 361 VAL D CG1 1 
ATOM   13625 C CG2 . VAL D 1 353 ? -9.599  71.869  8.151  1.00 49.48  ? 361 VAL D CG2 1 
ATOM   13626 N N   . ASP D 1 354 ? -12.718 68.414  7.067  1.00 51.99  ? 362 ASP D N   1 
ATOM   13627 C CA  . ASP D 1 354 ? -13.098 67.028  6.917  1.00 53.75  ? 362 ASP D CA  1 
ATOM   13628 C C   . ASP D 1 354 ? -11.910 66.271  6.329  1.00 70.81  ? 362 ASP D C   1 
ATOM   13629 O O   . ASP D 1 354 ? -11.769 66.191  5.111  1.00 78.49  ? 362 ASP D O   1 
ATOM   13630 C CB  . ASP D 1 354 ? -14.302 66.902  6.006  1.00 57.75  ? 362 ASP D CB  1 
ATOM   13631 C CG  . ASP D 1 354 ? -15.021 65.569  6.129  1.00 92.04  ? 362 ASP D CG  1 
ATOM   13632 O OD1 . ASP D 1 354 ? -14.364 64.577  6.547  1.00 93.01  ? 362 ASP D OD1 1 
ATOM   13633 O OD2 . ASP D 1 354 ? -16.229 65.549  5.855  1.00 137.88 ? 362 ASP D OD2 1 
ATOM   13634 N N   . LEU D 1 355 ? -11.062 65.698  7.198  1.00 62.68  ? 363 LEU D N   1 
ATOM   13635 C CA  . LEU D 1 355 ? -9.913  64.959  6.708  1.00 66.65  ? 363 LEU D CA  1 
ATOM   13636 C C   . LEU D 1 355 ? -10.311 63.781  5.801  1.00 90.98  ? 363 LEU D C   1 
ATOM   13637 O O   . LEU D 1 355 ? -9.444  63.144  5.223  1.00 101.86 ? 363 LEU D O   1 
ATOM   13638 C CB  . LEU D 1 355 ? -9.041  64.504  7.884  1.00 50.12  ? 363 LEU D CB  1 
ATOM   13639 C CG  . LEU D 1 355 ? -8.158  65.601  8.486  1.00 49.28  ? 363 LEU D CG  1 
ATOM   13640 C CD1 . LEU D 1 355 ? -7.227  65.038  9.508  1.00 46.51  ? 363 LEU D CD1 1 
ATOM   13641 C CD2 . LEU D 1 355 ? -7.307  66.290  7.439  1.00 50.97  ? 363 LEU D CD2 1 
ATOM   13642 N N   . ARG D 1 356 ? -11.598 63.451  5.656  1.00 85.26  ? 364 ARG D N   1 
ATOM   13643 C CA  . ARG D 1 356 ? -11.950 62.337  4.783  1.00 82.66  ? 364 ARG D CA  1 
ATOM   13644 C C   . ARG D 1 356 ? -11.541 62.601  3.333  1.00 80.84  ? 364 ARG D C   1 
ATOM   13645 O O   . ARG D 1 356 ? -11.212 61.682  2.621  1.00 96.12  ? 364 ARG D O   1 
ATOM   13646 C CB  . ARG D 1 356 ? -13.414 61.906  4.912  1.00 83.63  ? 364 ARG D CB  1 
ATOM   13647 C CG  . ARG D 1 356 ? -13.712 61.296  6.276  1.00 78.03  ? 364 ARG D CG  1 
ATOM   13648 C CD  . ARG D 1 356 ? -15.204 61.007  6.376  1.00 73.84  ? 364 ARG D CD  1 
ATOM   13649 N NE  . ARG D 1 356 ? -15.978 62.259  6.467  1.00 83.25  ? 364 ARG D NE  1 
ATOM   13650 C CZ  . ARG D 1 356 ? -17.295 62.350  6.714  1.00 91.57  ? 364 ARG D CZ  1 
ATOM   13651 N NH1 . ARG D 1 356 ? -18.003 61.308  7.105  1.00 105.38 ? 364 ARG D NH1 1 
ATOM   13652 N NH2 . ARG D 1 356 ? -17.951 63.484  6.665  1.00 110.23 ? 364 ARG D NH2 1 
ATOM   13653 N N   . SER D 1 357 ? -11.550 63.855  2.894  1.00 84.08  ? 365 SER D N   1 
ATOM   13654 C CA  . SER D 1 357 ? -11.103 64.286  1.580  1.00 69.93  ? 365 SER D CA  1 
ATOM   13655 C C   . SER D 1 357 ? -9.595  64.037  1.381  1.00 81.41  ? 365 SER D C   1 
ATOM   13656 O O   . SER D 1 357 ? -9.093  64.115  0.264  1.00 98.27  ? 365 SER D O   1 
ATOM   13657 C CB  . SER D 1 357 ? -11.425 65.759  1.404  1.00 67.08  ? 365 SER D CB  1 
ATOM   13658 O OG  . SER D 1 357 ? -10.719 66.568  2.352  1.00 49.78  ? 365 SER D OG  1 
ATOM   13659 N N   . LYS D 1 358 ? -8.849  63.717  2.435  1.00 69.50  ? 366 LYS D N   1 
ATOM   13660 C CA  . LYS D 1 358 ? -7.483  63.232  2.258  1.00 89.23  ? 366 LYS D CA  1 
ATOM   13661 C C   . LYS D 1 358 ? -7.348  61.732  2.578  1.00 103.79 ? 366 LYS D C   1 
ATOM   13662 O O   . LYS D 1 358 ? -6.236  61.211  2.470  1.00 102.53 ? 366 LYS D O   1 
ATOM   13663 C CB  . LYS D 1 358 ? -6.481  64.050  3.095  1.00 80.94  ? 366 LYS D CB  1 
ATOM   13664 C CG  . LYS D 1 358 ? -5.680  65.169  2.420  1.00 89.52  ? 366 LYS D CG  1 
ATOM   13665 C CD  . LYS D 1 358 ? -6.319  65.838  1.205  1.00 113.49 ? 366 LYS D CD  1 
ATOM   13666 C CE  . LYS D 1 358 ? -5.406  66.370  0.115  1.00 95.73  ? 366 LYS D CE  1 
ATOM   13667 N NZ  . LYS D 1 358 ? -6.262  66.840  -0.979 1.00 71.03  ? 366 LYS D NZ  1 
ATOM   13668 N N   . GLY D 1 359 ? -8.456  61.057  2.959  1.00 87.18  ? 367 GLY D N   1 
ATOM   13669 C CA  . GLY D 1 359 ? -8.453  59.664  3.423  1.00 88.34  ? 367 GLY D CA  1 
ATOM   13670 C C   . GLY D 1 359 ? -7.711  59.471  4.755  1.00 113.65 ? 367 GLY D C   1 
ATOM   13671 O O   . GLY D 1 359 ? -6.699  58.769  4.868  1.00 105.07 ? 367 GLY D O   1 
ATOM   13672 N N   . THR D 1 360 ? -8.191  60.159  5.791  1.00 102.06 ? 368 THR D N   1 
ATOM   13673 C CA  . THR D 1 360 ? -7.707  59.877  7.141  1.00 101.50 ? 368 THR D CA  1 
ATOM   13674 C C   . THR D 1 360 ? -8.744  60.455  8.089  1.00 99.63  ? 368 THR D C   1 
ATOM   13675 O O   . THR D 1 360 ? -9.743  60.949  7.590  1.00 104.02 ? 368 THR D O   1 
ATOM   13676 C CB  . THR D 1 360 ? -6.309  60.470  7.356  1.00 103.29 ? 368 THR D CB  1 
ATOM   13677 O OG1 . THR D 1 360 ? -5.803  60.290  8.664  1.00 92.15  ? 368 THR D OG1 1 
ATOM   13678 C CG2 . THR D 1 360 ? -6.272  61.976  7.269  1.00 121.78 ? 368 THR D CG2 1 
ATOM   13679 N N   . ASP D 1 361 ? -8.490  60.428  9.407  1.00 100.16 ? 369 ASP D N   1 
ATOM   13680 C CA  . ASP D 1 361 ? -9.404  60.969  10.412 1.00 85.24  ? 369 ASP D CA  1 
ATOM   13681 C C   . ASP D 1 361 ? -8.668  61.918  11.368 1.00 87.85  ? 369 ASP D C   1 
ATOM   13682 O O   . ASP D 1 361 ? -7.457  61.791  11.602 1.00 63.66  ? 369 ASP D O   1 
ATOM   13683 C CB  . ASP D 1 361 ? -10.073 59.837  11.176 1.00 80.47  ? 369 ASP D CB  1 
ATOM   13684 C CG  . ASP D 1 361 ? -9.099  58.981  11.990 1.00 98.26  ? 369 ASP D CG  1 
ATOM   13685 O OD1 . ASP D 1 361 ? -8.753  59.355  13.159 1.00 73.60  ? 369 ASP D OD1 1 
ATOM   13686 O OD2 . ASP D 1 361 ? -8.642  57.957  11.437 1.00 95.97  ? 369 ASP D OD2 1 
ATOM   13687 N N   . GLY D 1 362 ? -9.431  62.837  11.985 1.00 80.00  ? 370 GLY D N   1 
ATOM   13688 C CA  . GLY D 1 362 ? -8.864  63.776  12.937 1.00 81.36  ? 370 GLY D CA  1 
ATOM   13689 C C   . GLY D 1 362 ? -8.285  63.075  14.171 1.00 99.02  ? 370 GLY D C   1 
ATOM   13690 O O   . GLY D 1 362 ? -7.485  63.664  14.898 1.00 112.49 ? 370 GLY D O   1 
ATOM   13691 N N   . GLY D 1 363 ? -8.740  61.837  14.420 1.00 83.65  ? 371 GLY D N   1 
ATOM   13692 C CA  . GLY D 1 363 ? -8.359  61.106  15.614 1.00 109.19 ? 371 GLY D CA  1 
ATOM   13693 C C   . GLY D 1 363 ? -6.849  60.934  15.616 1.00 118.19 ? 371 GLY D C   1 
ATOM   13694 O O   . GLY D 1 363 ? -6.158  61.220  16.609 1.00 109.12 ? 371 GLY D O   1 
ATOM   13695 N N   . ARG D 1 364 ? -6.381  60.493  14.437 1.00 113.14 ? 372 ARG D N   1 
ATOM   13696 C CA  . ARG D 1 364 ? -4.990  60.165  14.173 1.00 99.87  ? 372 ARG D CA  1 
ATOM   13697 C C   . ARG D 1 364 ? -4.218  61.461  13.993 1.00 104.92 ? 372 ARG D C   1 
ATOM   13698 O O   . ARG D 1 364 ? -3.199  61.653  14.665 1.00 103.43 ? 372 ARG D O   1 
ATOM   13699 C CB  . ARG D 1 364 ? -4.897  59.347  12.881 1.00 70.20  ? 372 ARG D CB  1 
ATOM   13700 C CG  . ARG D 1 364 ? -5.422  57.930  13.020 1.00 83.64  ? 372 ARG D CG  1 
ATOM   13701 C CD  . ARG D 1 364 ? -5.586  57.237  11.647 1.00 99.66  ? 372 ARG D CD  1 
ATOM   13702 N NE  . ARG D 1 364 ? -6.521  56.119  11.849 1.00 85.46  ? 372 ARG D NE  1 
ATOM   13703 C CZ  . ARG D 1 364 ? -6.236  54.971  12.444 1.00 88.25  ? 372 ARG D CZ  1 
ATOM   13704 N NH1 . ARG D 1 364 ? -4.974  54.580  12.602 1.00 82.65  ? 372 ARG D NH1 1 
ATOM   13705 N NH2 . ARG D 1 364 ? -7.238  54.193  12.815 1.00 69.77  ? 372 ARG D NH2 1 
ATOM   13706 N N   . ALA D 1 365 ? -4.758  62.324  13.114 1.00 92.27  ? 373 ALA D N   1 
ATOM   13707 C CA  . ALA D 1 365 ? -4.066  63.519  12.670 1.00 83.70  ? 373 ALA D CA  1 
ATOM   13708 C C   . ALA D 1 365 ? -3.749  64.367  13.886 1.00 110.70 ? 373 ALA D C   1 
ATOM   13709 O O   . ALA D 1 365 ? -2.612  64.759  14.085 1.00 114.75 ? 373 ALA D O   1 
ATOM   13710 C CB  . ALA D 1 365 ? -4.913  64.265  11.676 1.00 76.90  ? 373 ALA D CB  1 
ATOM   13711 N N   . GLU D 1 366 ? -4.753  64.583  14.738 1.00 118.30 ? 374 GLU D N   1 
ATOM   13712 C CA  . GLU D 1 366 ? -4.600  65.321  15.982 1.00 103.02 ? 374 GLU D CA  1 
ATOM   13713 C C   . GLU D 1 366 ? -3.269  64.948  16.632 1.00 106.94 ? 374 GLU D C   1 
ATOM   13714 O O   . GLU D 1 366 ? -2.440  65.820  16.893 1.00 88.31  ? 374 GLU D O   1 
ATOM   13715 C CB  . GLU D 1 366 ? -5.751  64.845  16.879 1.00 117.72 ? 374 GLU D CB  1 
ATOM   13716 C CG  . GLU D 1 366 ? -5.654  65.211  18.358 1.00 96.73  ? 374 GLU D CG  1 
ATOM   13717 C CD  . GLU D 1 366 ? -7.001  64.927  18.982 1.00 113.32 ? 374 GLU D CD  1 
ATOM   13718 O OE1 . GLU D 1 366 ? -7.444  63.745  19.087 1.00 104.94 ? 374 GLU D OE1 1 
ATOM   13719 O OE2 . GLU D 1 366 ? -7.589  65.960  19.360 1.00 124.57 ? 374 GLU D OE2 1 
ATOM   13720 N N   . LYS D 1 367 ? -3.071  63.632  16.849 1.00 98.13  ? 375 LYS D N   1 
ATOM   13721 C CA  . LYS D 1 367 ? -1.999  63.117  17.691 1.00 91.55  ? 375 LYS D CA  1 
ATOM   13722 C C   . LYS D 1 367 ? -0.628  63.335  17.046 1.00 94.46  ? 375 LYS D C   1 
ATOM   13723 O O   . LYS D 1 367 ? 0.322   63.684  17.754 1.00 106.42 ? 375 LYS D O   1 
ATOM   13724 C CB  . LYS D 1 367 ? -2.261  61.646  18.028 1.00 93.56  ? 375 LYS D CB  1 
ATOM   13725 C CG  . LYS D 1 367 ? -3.360  61.411  19.061 1.00 114.94 ? 375 LYS D CG  1 
ATOM   13726 C CD  . LYS D 1 367 ? -3.223  62.121  20.406 1.00 125.25 ? 375 LYS D CD  1 
ATOM   13727 C CE  . LYS D 1 367 ? -4.573  62.315  21.063 1.00 136.62 ? 375 LYS D CE  1 
ATOM   13728 N NZ  . LYS D 1 367 ? -4.821  63.515  21.881 1.00 103.60 ? 375 LYS D NZ  1 
ATOM   13729 N N   . VAL D 1 368 ? -0.536  63.105  15.725 1.00 74.91  ? 376 VAL D N   1 
ATOM   13730 C CA  . VAL D 1 368 ? 0.643   63.331  14.909 1.00 67.57  ? 376 VAL D CA  1 
ATOM   13731 C C   . VAL D 1 368 ? 1.012   64.801  15.003 1.00 73.40  ? 376 VAL D C   1 
ATOM   13732 O O   . VAL D 1 368 ? 2.128   65.157  15.395 1.00 73.91  ? 376 VAL D O   1 
ATOM   13733 C CB  . VAL D 1 368 ? 0.255   62.998  13.450 1.00 70.16  ? 376 VAL D CB  1 
ATOM   13734 C CG1 . VAL D 1 368 ? 1.270   63.465  12.390 1.00 51.29  ? 376 VAL D CG1 1 
ATOM   13735 C CG2 . VAL D 1 368 ? -0.063  61.509  13.315 1.00 72.92  ? 376 VAL D CG2 1 
ATOM   13736 N N   . LEU D 1 369 ? 0.063   65.643  14.559 1.00 74.47  ? 377 LEU D N   1 
ATOM   13737 C CA  . LEU D 1 369 ? 0.295   67.073  14.423 1.00 93.92  ? 377 LEU D CA  1 
ATOM   13738 C C   . LEU D 1 369 ? 0.778   67.550  15.775 1.00 86.15  ? 377 LEU D C   1 
ATOM   13739 O O   . LEU D 1 369 ? 1.654   68.407  15.830 1.00 75.05  ? 377 LEU D O   1 
ATOM   13740 C CB  . LEU D 1 369 ? -0.987  67.801  14.037 1.00 106.13 ? 377 LEU D CB  1 
ATOM   13741 C CG  . LEU D 1 369 ? -1.446  67.651  12.587 1.00 107.76 ? 377 LEU D CG  1 
ATOM   13742 C CD1 . LEU D 1 369 ? -2.959  67.741  12.478 1.00 103.94 ? 377 LEU D CD1 1 
ATOM   13743 C CD2 . LEU D 1 369 ? -0.807  68.846  11.913 1.00 97.70  ? 377 LEU D CD2 1 
ATOM   13744 N N   . GLU D 1 370 ? 0.215   66.938  16.828 1.00 57.49  ? 378 GLU D N   1 
ATOM   13745 C CA  . GLU D 1 370 ? 0.605   67.270  18.189 1.00 61.77  ? 378 GLU D CA  1 
ATOM   13746 C C   . GLU D 1 370 ? 2.098   67.021  18.358 1.00 64.38  ? 378 GLU D C   1 
ATOM   13747 O O   . GLU D 1 370 ? 2.796   67.840  18.967 1.00 85.25  ? 378 GLU D O   1 
ATOM   13748 C CB  . GLU D 1 370 ? -0.227  66.524  19.237 1.00 57.12  ? 378 GLU D CB  1 
ATOM   13749 C CG  . GLU D 1 370 ? 0.319   66.620  20.662 1.00 48.88  ? 378 GLU D CG  1 
ATOM   13750 C CD  . GLU D 1 370 ? -0.270  65.696  21.701 1.00 68.88  ? 378 GLU D CD  1 
ATOM   13751 O OE1 . GLU D 1 370 ? -1.085  64.687  21.441 1.00 61.09  ? 378 GLU D OE1 1 
ATOM   13752 O OE2 . GLU D 1 370 ? 0.181   66.140  22.824 1.00 46.17  ? 378 GLU D OE2 1 
ATOM   13753 N N   . ALA D 1 371 ? 2.545   65.855  17.878 1.00 70.78  ? 379 ALA D N   1 
ATOM   13754 C CA  . ALA D 1 371 ? 3.927   65.438  18.030 1.00 80.48  ? 379 ALA D CA  1 
ATOM   13755 C C   . ALA D 1 371 ? 4.844   66.331  17.187 1.00 87.25  ? 379 ALA D C   1 
ATOM   13756 O O   . ALA D 1 371 ? 6.055   66.366  17.418 1.00 70.28  ? 379 ALA D O   1 
ATOM   13757 C CB  . ALA D 1 371 ? 4.051   63.981  17.695 1.00 92.49  ? 379 ALA D CB  1 
ATOM   13758 N N   . CYS D 1 372 ? 4.262   67.100  16.257 1.00 103.24 ? 380 CYS D N   1 
ATOM   13759 C CA  . CYS D 1 372 ? 5.033   68.036  15.446 1.00 112.92 ? 380 CYS D CA  1 
ATOM   13760 C C   . CYS D 1 372 ? 4.845   69.464  15.957 1.00 130.61 ? 380 CYS D C   1 
ATOM   13761 O O   . CYS D 1 372 ? 5.193   70.424  15.270 1.00 150.86 ? 380 CYS D O   1 
ATOM   13762 C CB  . CYS D 1 372 ? 4.596   68.046  13.989 1.00 92.25  ? 380 CYS D CB  1 
ATOM   13763 S SG  . CYS D 1 372 ? 4.236   66.414  13.314 1.00 148.77 ? 380 CYS D SG  1 
ATOM   13764 N N   . SER D 1 373 ? 4.304   69.591  17.177 1.00 99.77  ? 381 SER D N   1 
ATOM   13765 C CA  . SER D 1 373 ? 4.122   70.873  17.848 1.00 88.22  ? 381 SER D CA  1 
ATOM   13766 C C   . SER D 1 373 ? 3.060   71.742  17.187 1.00 86.28  ? 381 SER D C   1 
ATOM   13767 O O   . SER D 1 373 ? 3.072   72.956  17.388 1.00 104.57 ? 381 SER D O   1 
ATOM   13768 C CB  . SER D 1 373 ? 5.392   71.611  18.001 1.00 73.59  ? 381 SER D CB  1 
ATOM   13769 O OG  . SER D 1 373 ? 6.308   70.778  18.709 1.00 81.28  ? 381 SER D OG  1 
ATOM   13770 N N   . ILE D 1 374 ? 2.146   71.106  16.443 1.00 71.77  ? 382 ILE D N   1 
ATOM   13771 C CA  . ILE D 1 374 ? 0.997   71.754  15.834 1.00 85.81  ? 382 ILE D CA  1 
ATOM   13772 C C   . ILE D 1 374 ? -0.227  71.333  16.644 1.00 98.00  ? 382 ILE D C   1 
ATOM   13773 O O   . ILE D 1 374 ? -0.720  70.210  16.531 1.00 90.12  ? 382 ILE D O   1 
ATOM   13774 C CB  . ILE D 1 374 ? 0.901   71.344  14.346 1.00 67.70  ? 382 ILE D CB  1 
ATOM   13775 C CG1 . ILE D 1 374 ? 2.123   71.811  13.616 1.00 64.15  ? 382 ILE D CG1 1 
ATOM   13776 C CG2 . ILE D 1 374 ? -0.397  71.743  13.625 1.00 48.70  ? 382 ILE D CG2 1 
ATOM   13777 C CD1 . ILE D 1 374 ? 2.105   71.458  12.147 1.00 88.43  ? 382 ILE D CD1 1 
ATOM   13778 N N   . ALA D 1 375 ? -0.692  72.249  17.491 1.00 78.89  ? 383 ALA D N   1 
ATOM   13779 C CA  . ALA D 1 375 ? -1.798  71.934  18.369 1.00 72.65  ? 383 ALA D CA  1 
ATOM   13780 C C   . ALA D 1 375 ? -3.112  72.218  17.645 1.00 73.12  ? 383 ALA D C   1 
ATOM   13781 O O   . ALA D 1 375 ? -3.364  73.363  17.302 1.00 75.15  ? 383 ALA D O   1 
ATOM   13782 C CB  . ALA D 1 375 ? -1.650  72.716  19.667 1.00 68.72  ? 383 ALA D CB  1 
ATOM   13783 N N   . CYS D 1 376 ? -3.910  71.162  17.395 1.00 67.10  ? 384 CYS D N   1 
ATOM   13784 C CA  . CYS D 1 376 ? -5.330  71.317  17.111 1.00 79.44  ? 384 CYS D CA  1 
ATOM   13785 C C   . CYS D 1 376 ? -6.165  70.290  17.888 1.00 96.10  ? 384 CYS D C   1 
ATOM   13786 O O   . CYS D 1 376 ? -5.652  69.585  18.754 1.00 113.03 ? 384 CYS D O   1 
ATOM   13787 C CB  . CYS D 1 376 ? -5.521  71.236  15.619 1.00 70.76  ? 384 CYS D CB  1 
ATOM   13788 S SG  . CYS D 1 376 ? -4.918  69.625  15.079 1.00 100.55 ? 384 CYS D SG  1 
ATOM   13789 N N   . ASN D 1 377 ? -7.471  70.221  17.619 1.00 110.24 ? 385 ASN D N   1 
ATOM   13790 C CA  . ASN D 1 377 ? -8.316  69.255  18.317 1.00 90.56  ? 385 ASN D CA  1 
ATOM   13791 C C   . ASN D 1 377 ? -9.127  68.532  17.241 1.00 98.15  ? 385 ASN D C   1 
ATOM   13792 O O   . ASN D 1 377 ? -9.490  69.161  16.225 1.00 88.58  ? 385 ASN D O   1 
ATOM   13793 C CB  . ASN D 1 377 ? -9.127  69.937  19.422 1.00 80.17  ? 385 ASN D CB  1 
ATOM   13794 C CG  . ASN D 1 377 ? -10.161 70.891  18.855 1.00 116.53 ? 385 ASN D CG  1 
ATOM   13795 O OD1 . ASN D 1 377 ? -9.873  72.067  18.573 1.00 134.35 ? 385 ASN D OD1 1 
ATOM   13796 N ND2 . ASN D 1 377 ? -11.377 70.394  18.643 1.00 122.99 ? 385 ASN D ND2 1 
ATOM   13797 N N   . LYS D 1 378 ? -9.320  67.214  17.422 1.00 88.53  ? 386 LYS D N   1 
ATOM   13798 C CA  . LYS D 1 378 ? -10.122 66.453  16.455 1.00 95.51  ? 386 LYS D CA  1 
ATOM   13799 C C   . LYS D 1 378 ? -11.566 66.948  16.581 1.00 62.65  ? 386 LYS D C   1 
ATOM   13800 O O   . LYS D 1 378 ? -11.875 67.570  17.576 1.00 65.34  ? 386 LYS D O   1 
ATOM   13801 C CB  . LYS D 1 378 ? -10.049 64.930  16.654 1.00 81.30  ? 386 LYS D CB  1 
ATOM   13802 C CG  . LYS D 1 378 ? -10.390 64.622  18.097 1.00 98.95  ? 386 LYS D CG  1 
ATOM   13803 C CD  . LYS D 1 378 ? -10.946 63.270  18.531 1.00 109.79 ? 386 LYS D CD  1 
ATOM   13804 C CE  . LYS D 1 378 ? -11.320 63.388  19.992 1.00 106.86 ? 386 LYS D CE  1 
ATOM   13805 N NZ  . LYS D 1 378 ? -10.055 63.412  20.733 1.00 145.66 ? 386 LYS D NZ  1 
ATOM   13806 N N   . ASN D 1 379 ? -12.467 66.518  15.718 1.00 43.93  ? 387 ASN D N   1 
ATOM   13807 C CA  . ASN D 1 379 ? -13.838 66.978  15.837 1.00 72.77  ? 387 ASN D CA  1 
ATOM   13808 C C   . ASN D 1 379 ? -14.687 66.388  14.709 1.00 83.15  ? 387 ASN D C   1 
ATOM   13809 O O   . ASN D 1 379 ? -14.327 66.500  13.528 1.00 92.37  ? 387 ASN D O   1 
ATOM   13810 C CB  . ASN D 1 379 ? -13.860 68.504  15.837 1.00 99.34  ? 387 ASN D CB  1 
ATOM   13811 C CG  . ASN D 1 379 ? -15.118 69.084  16.442 1.00 118.10 ? 387 ASN D CG  1 
ATOM   13812 O OD1 . ASN D 1 379 ? -16.237 68.616  16.168 1.00 137.34 ? 387 ASN D OD1 1 
ATOM   13813 N ND2 . ASN D 1 379 ? -14.941 70.089  17.305 1.00 81.53  ? 387 ASN D ND2 1 
ATOM   13814 N N   . THR D 1 380 ? -15.800 65.746  15.077 1.00 82.72  ? 388 THR D N   1 
ATOM   13815 C CA  . THR D 1 380 ? -16.596 65.017  14.099 1.00 98.90  ? 388 THR D CA  1 
ATOM   13816 C C   . THR D 1 380 ? -17.195 65.989  13.088 1.00 94.84  ? 388 THR D C   1 
ATOM   13817 O O   . THR D 1 380 ? -17.463 67.135  13.418 1.00 97.64  ? 388 THR D O   1 
ATOM   13818 C CB  . THR D 1 380 ? -17.643 64.136  14.785 1.00 92.91  ? 388 THR D CB  1 
ATOM   13819 O OG1 . THR D 1 380 ? -18.301 65.011  15.694 1.00 110.51 ? 388 THR D OG1 1 
ATOM   13820 C CG2 . THR D 1 380 ? -17.018 63.023  15.608 1.00 89.27  ? 388 THR D CG2 1 
ATOM   13821 N N   . CYS D 1 381 ? -17.361 65.535  11.848 1.00 90.05  ? 389 CYS D N   1 
ATOM   13822 C CA  . CYS D 1 381 ? -18.036 66.335  10.845 1.00 120.41 ? 389 CYS D CA  1 
ATOM   13823 C C   . CYS D 1 381 ? -19.455 65.811  10.713 1.00 121.21 ? 389 CYS D C   1 
ATOM   13824 O O   . CYS D 1 381 ? -19.717 64.655  11.018 1.00 148.76 ? 389 CYS D O   1 
ATOM   13825 C CB  . CYS D 1 381 ? -17.364 66.227  9.484  1.00 126.18 ? 389 CYS D CB  1 
ATOM   13826 S SG  . CYS D 1 381 ? -15.616 66.640  9.617  1.00 86.59  ? 389 CYS D SG  1 
ATOM   13827 N N   . PRO D 1 382 ? -20.401 66.626  10.199 1.00 103.78 ? 390 PRO D N   1 
ATOM   13828 C CA  . PRO D 1 382 ? -21.717 66.114  9.825  1.00 111.86 ? 390 PRO D CA  1 
ATOM   13829 C C   . PRO D 1 382 ? -21.604 64.764  9.104  1.00 119.87 ? 390 PRO D C   1 
ATOM   13830 O O   . PRO D 1 382 ? -20.799 64.602  8.162  1.00 75.82  ? 390 PRO D O   1 
ATOM   13831 C CB  . PRO D 1 382 ? -22.216 67.252  8.912  1.00 119.44 ? 390 PRO D CB  1 
ATOM   13832 C CG  . PRO D 1 382 ? -21.603 68.483  9.499  1.00 131.61 ? 390 PRO D CG  1 
ATOM   13833 C CD  . PRO D 1 382 ? -20.214 68.054  9.898  1.00 117.90 ? 390 PRO D CD  1 
ATOM   13834 N N   . GLY D 1 383 ? -22.409 63.808  9.611  1.00 118.09 ? 391 GLY D N   1 
ATOM   13835 C CA  . GLY D 1 383 ? -22.535 62.474  9.044  1.00 129.47 ? 391 GLY D CA  1 
ATOM   13836 C C   . GLY D 1 383 ? -21.421 61.535  9.519  1.00 112.34 ? 391 GLY D C   1 
ATOM   13837 O O   . GLY D 1 383 ? -21.139 60.524  8.881  1.00 82.52  ? 391 GLY D O   1 
ATOM   13838 N N   . ASP D 1 384 ? -20.748 61.892  10.615 1.00 114.99 ? 392 ASP D N   1 
ATOM   13839 C CA  . ASP D 1 384 ? -19.722 60.984  11.118 1.00 127.38 ? 392 ASP D CA  1 
ATOM   13840 C C   . ASP D 1 384 ? -20.393 59.736  11.649 1.00 136.98 ? 392 ASP D C   1 
ATOM   13841 O O   . ASP D 1 384 ? -21.413 59.839  12.340 1.00 135.86 ? 392 ASP D O   1 
ATOM   13842 C CB  . ASP D 1 384 ? -18.813 61.618  12.154 1.00 102.79 ? 392 ASP D CB  1 
ATOM   13843 C CG  . ASP D 1 384 ? -17.539 62.186  11.565 1.00 90.60  ? 392 ASP D CG  1 
ATOM   13844 O OD1 . ASP D 1 384 ? -17.527 62.487  10.360 1.00 82.32  ? 392 ASP D OD1 1 
ATOM   13845 O OD2 . ASP D 1 384 ? -16.577 62.300  12.320 1.00 115.60 ? 392 ASP D OD2 1 
ATOM   13846 N N   . ARG D 1 385 ? -19.778 58.571  11.385 1.00 127.68 ? 393 ARG D N   1 
ATOM   13847 C CA  . ARG D 1 385 ? -20.301 57.345  11.981 1.00 93.84  ? 393 ARG D CA  1 
ATOM   13848 C C   . ARG D 1 385 ? -19.915 57.266  13.471 1.00 81.53  ? 393 ARG D C   1 
ATOM   13849 O O   . ARG D 1 385 ? -20.652 57.777  14.326 1.00 66.31  ? 393 ARG D O   1 
ATOM   13850 C CB  . ARG D 1 385 ? -20.412 56.208  10.946 1.00 88.82  ? 393 ARG D CB  1 
ATOM   13851 C CG  . ARG D 1 385 ? -21.805 56.198  10.323 1.00 72.33  ? 393 ARG D CG  1 
ATOM   13852 C CD  . ARG D 1 385 ? -22.765 55.690  11.457 1.00 92.27  ? 393 ARG D CD  1 
ATOM   13853 N NE  . ARG D 1 385 ? -24.138 56.174  11.694 1.00 115.70 ? 393 ARG D NE  1 
ATOM   13854 C CZ  . ARG D 1 385 ? -25.232 56.081  10.925 1.00 133.18 ? 393 ARG D CZ  1 
ATOM   13855 N NH1 . ARG D 1 385 ? -25.220 55.388  9.791  1.00 117.54 ? 393 ARG D NH1 1 
ATOM   13856 N NH2 . ARG D 1 385 ? -26.344 56.686  11.313 1.00 112.33 ? 393 ARG D NH2 1 
ATOM   13857 N N   . SER D 1 386 ? -18.698 56.782  13.790 1.00 101.69 ? 394 SER D N   1 
ATOM   13858 C CA  . SER D 1 386 ? -18.251 56.587  15.174 1.00 96.62  ? 394 SER D CA  1 
ATOM   13859 C C   . SER D 1 386 ? -17.406 57.748  15.704 1.00 74.88  ? 394 SER D C   1 
ATOM   13860 O O   . SER D 1 386 ? -16.415 58.154  15.088 1.00 74.98  ? 394 SER D O   1 
ATOM   13861 C CB  . SER D 1 386 ? -17.493 55.292  15.377 1.00 107.76 ? 394 SER D CB  1 
ATOM   13862 O OG  . SER D 1 386 ? -16.961 55.191  16.696 1.00 99.77  ? 394 SER D OG  1 
ATOM   13863 N N   . ALA D 1 387 ? -17.827 58.279  16.855 1.00 63.49  ? 395 ALA D N   1 
ATOM   13864 C CA  . ALA D 1 387 ? -17.145 59.427  17.442 1.00 76.86  ? 395 ALA D CA  1 
ATOM   13865 C C   . ALA D 1 387 ? -15.819 58.977  18.049 1.00 96.82  ? 395 ALA D C   1 
ATOM   13866 O O   . ALA D 1 387 ? -15.047 59.818  18.479 1.00 98.91  ? 395 ALA D O   1 
ATOM   13867 C CB  . ALA D 1 387 ? -18.027 60.177  18.447 1.00 73.19  ? 395 ALA D CB  1 
ATOM   13868 N N   . LEU D 1 388 ? -15.517 57.665  18.042 1.00 111.61 ? 396 LEU D N   1 
ATOM   13869 C CA  . LEU D 1 388 ? -14.155 57.174  18.286 1.00 96.87  ? 396 LEU D CA  1 
ATOM   13870 C C   . LEU D 1 388 ? -13.281 57.431  17.052 1.00 116.10 ? 396 LEU D C   1 
ATOM   13871 O O   . LEU D 1 388 ? -12.077 57.595  17.201 1.00 137.05 ? 396 LEU D O   1 
ATOM   13872 C CB  . LEU D 1 388 ? -14.080 55.738  18.798 1.00 101.94 ? 396 LEU D CB  1 
ATOM   13873 C CG  . LEU D 1 388 ? -14.689 55.466  20.196 1.00 122.71 ? 396 LEU D CG  1 
ATOM   13874 C CD1 . LEU D 1 388 ? -14.688 53.995  20.641 1.00 99.07  ? 396 LEU D CD1 1 
ATOM   13875 C CD2 . LEU D 1 388 ? -14.230 56.302  21.408 1.00 94.04  ? 396 LEU D CD2 1 
ATOM   13876 N N   . ARG D 1 389 ? -13.883 57.572  15.850 1.00 112.01 ? 397 ARG D N   1 
ATOM   13877 C CA  . ARG D 1 389 ? -13.225 57.985  14.611 1.00 102.19 ? 397 ARG D CA  1 
ATOM   13878 C C   . ARG D 1 389 ? -13.813 59.303  14.069 1.00 102.05 ? 397 ARG D C   1 
ATOM   13879 O O   . ARG D 1 389 ? -14.535 59.326  13.059 1.00 99.52  ? 397 ARG D O   1 
ATOM   13880 C CB  . ARG D 1 389 ? -13.253 56.856  13.575 1.00 88.92  ? 397 ARG D CB  1 
ATOM   13881 C CG  . ARG D 1 389 ? -12.550 57.273  12.284 1.00 94.10  ? 397 ARG D CG  1 
ATOM   13882 C CD  . ARG D 1 389 ? -12.542 56.482  11.011 1.00 103.09 ? 397 ARG D CD  1 
ATOM   13883 N NE  . ARG D 1 389 ? -11.804 55.228  11.208 1.00 113.36 ? 397 ARG D NE  1 
ATOM   13884 C CZ  . ARG D 1 389 ? -10.580 54.966  10.757 1.00 122.75 ? 397 ARG D CZ  1 
ATOM   13885 N NH1 . ARG D 1 389 ? -9.903  55.839  10.022 1.00 120.78 ? 397 ARG D NH1 1 
ATOM   13886 N NH2 . ARG D 1 389 ? -10.033 53.799  11.037 1.00 98.01  ? 397 ARG D NH2 1 
ATOM   13887 N N   . PRO D 1 390 ? -13.442 60.455  14.677 1.00 91.95  ? 398 PRO D N   1 
ATOM   13888 C CA  . PRO D 1 390 ? -13.850 61.767  14.149 1.00 87.33  ? 398 PRO D CA  1 
ATOM   13889 C C   . PRO D 1 390 ? -13.151 62.070  12.820 1.00 79.03  ? 398 PRO D C   1 
ATOM   13890 O O   . PRO D 1 390 ? -11.953 61.887  12.662 1.00 83.68  ? 398 PRO D O   1 
ATOM   13891 C CB  . PRO D 1 390 ? -13.464 62.770  15.235 1.00 96.78  ? 398 PRO D CB  1 
ATOM   13892 C CG  . PRO D 1 390 ? -12.345 62.074  15.966 1.00 115.60 ? 398 PRO D CG  1 
ATOM   13893 C CD  . PRO D 1 390 ? -12.504 60.555  15.823 1.00 106.14 ? 398 PRO D CD  1 
ATOM   13894 N N   . SER D 1 391 ? -13.902 62.570  11.855 1.00 64.77  ? 399 SER D N   1 
ATOM   13895 C CA  . SER D 1 391 ? -13.373 62.802  10.516 1.00 77.87  ? 399 SER D CA  1 
ATOM   13896 C C   . SER D 1 391 ? -12.552 64.083  10.436 1.00 94.79  ? 399 SER D C   1 
ATOM   13897 O O   . SER D 1 391 ? -11.677 64.175  9.562  1.00 103.50 ? 399 SER D O   1 
ATOM   13898 C CB  . SER D 1 391 ? -14.468 62.871  9.518  1.00 63.39  ? 399 SER D CB  1 
ATOM   13899 O OG  . SER D 1 391 ? -15.214 61.679  9.553  1.00 76.96  ? 399 SER D OG  1 
ATOM   13900 N N   . GLY D 1 392 ? -12.817 65.003  11.401 1.00 81.52  ? 400 GLY D N   1 
ATOM   13901 C CA  . GLY D 1 392 ? -12.509 66.420  11.258 1.00 72.71  ? 400 GLY D CA  1 
ATOM   13902 C C   . GLY D 1 392 ? -11.398 66.912  12.188 1.00 74.91  ? 400 GLY D C   1 
ATOM   13903 O O   . GLY D 1 392 ? -11.086 66.290  13.201 1.00 93.93  ? 400 GLY D O   1 
ATOM   13904 N N   . LEU D 1 393 ? -10.799 68.037  11.808 1.00 76.89  ? 401 LEU D N   1 
ATOM   13905 C CA  . LEU D 1 393 ? -9.928  68.806  12.676 1.00 102.87 ? 401 LEU D CA  1 
ATOM   13906 C C   . LEU D 1 393 ? -10.559 70.181  12.811 1.00 133.66 ? 401 LEU D C   1 
ATOM   13907 O O   . LEU D 1 393 ? -10.913 70.806  11.794 1.00 126.47 ? 401 LEU D O   1 
ATOM   13908 C CB  . LEU D 1 393 ? -8.564  68.940  12.023 1.00 88.41  ? 401 LEU D CB  1 
ATOM   13909 C CG  . LEU D 1 393 ? -7.642  67.738  12.205 1.00 98.79  ? 401 LEU D CG  1 
ATOM   13910 C CD1 . LEU D 1 393 ? -6.361  68.044  11.472 1.00 97.26  ? 401 LEU D CD1 1 
ATOM   13911 C CD2 . LEU D 1 393 ? -7.428  67.430  13.682 1.00 97.61  ? 401 LEU D CD2 1 
ATOM   13912 N N   . ARG D 1 394 ? -10.736 70.603  14.069 1.00 118.73 ? 402 ARG D N   1 
ATOM   13913 C CA  . ARG D 1 394 ? -11.211 71.953  14.283 1.00 91.15  ? 402 ARG D CA  1 
ATOM   13914 C C   . ARG D 1 394 ? -9.986  72.857  14.411 1.00 102.07 ? 402 ARG D C   1 
ATOM   13915 O O   . ARG D 1 394 ? -9.117  72.636  15.270 1.00 88.93  ? 402 ARG D O   1 
ATOM   13916 C CB  . ARG D 1 394 ? -12.094 72.013  15.522 1.00 89.84  ? 402 ARG D CB  1 
ATOM   13917 C CG  . ARG D 1 394 ? -12.696 73.402  15.714 1.00 108.92 ? 402 ARG D CG  1 
ATOM   13918 C CD  . ARG D 1 394 ? -13.289 73.734  17.089 1.00 78.49  ? 402 ARG D CD  1 
ATOM   13919 N NE  . ARG D 1 394 ? -12.292 73.670  18.153 1.00 82.16  ? 402 ARG D NE  1 
ATOM   13920 C CZ  . ARG D 1 394 ? -12.601 73.864  19.421 1.00 95.34  ? 402 ARG D CZ  1 
ATOM   13921 N NH1 . ARG D 1 394 ? -13.834 74.129  19.802 1.00 78.83  ? 402 ARG D NH1 1 
ATOM   13922 N NH2 . ARG D 1 394 ? -11.650 73.758  20.327 1.00 139.50 ? 402 ARG D NH2 1 
ATOM   13923 N N   . LEU D 1 395 ? -9.936  73.871  13.529 1.00 98.57  ? 403 LEU D N   1 
ATOM   13924 C CA  . LEU D 1 395 ? -8.795  74.762  13.426 1.00 94.88  ? 403 LEU D CA  1 
ATOM   13925 C C   . LEU D 1 395 ? -9.293  76.194  13.618 1.00 106.96 ? 403 LEU D C   1 
ATOM   13926 O O   . LEU D 1 395 ? -10.343 76.581  13.076 1.00 90.50  ? 403 LEU D O   1 
ATOM   13927 C CB  . LEU D 1 395 ? -8.182  74.631  12.037 1.00 90.16  ? 403 LEU D CB  1 
ATOM   13928 C CG  . LEU D 1 395 ? -7.689  73.259  11.601 1.00 85.31  ? 403 LEU D CG  1 
ATOM   13929 C CD1 . LEU D 1 395 ? -7.005  73.534  10.254 1.00 84.43  ? 403 LEU D CD1 1 
ATOM   13930 C CD2 . LEU D 1 395 ? -6.664  72.749  12.564 1.00 68.09  ? 403 LEU D CD2 1 
ATOM   13931 N N   . GLY D 1 396 ? -8.559  76.952  14.435 1.00 82.70  ? 404 GLY D N   1 
ATOM   13932 C CA  . GLY D 1 396 ? -8.934  78.327  14.665 1.00 77.59  ? 404 GLY D CA  1 
ATOM   13933 C C   . GLY D 1 396 ? -7.708  79.221  14.738 1.00 107.34 ? 404 GLY D C   1 
ATOM   13934 O O   . GLY D 1 396 ? -6.570  78.787  15.043 1.00 95.12  ? 404 GLY D O   1 
ATOM   13935 N N   . THR D 1 397 ? -8.005  80.512  14.528 1.00 96.30  ? 405 THR D N   1 
ATOM   13936 C CA  . THR D 1 397 ? -6.951  81.492  14.368 1.00 103.03 ? 405 THR D CA  1 
ATOM   13937 C C   . THR D 1 397 ? -6.697  82.377  15.579 1.00 122.45 ? 405 THR D C   1 
ATOM   13938 O O   . THR D 1 397 ? -5.629  82.972  15.587 1.00 119.74 ? 405 THR D O   1 
ATOM   13939 C CB  . THR D 1 397 ? -7.223  82.282  13.096 1.00 94.94  ? 405 THR D CB  1 
ATOM   13940 O OG1 . THR D 1 397 ? -8.419  83.010  13.329 1.00 123.90 ? 405 THR D OG1 1 
ATOM   13941 C CG2 . THR D 1 397 ? -7.357  81.337  11.903 1.00 70.13  ? 405 THR D CG2 1 
ATOM   13942 N N   . PRO D 1 398 ? -7.587  82.497  16.597 1.00 120.06 ? 406 PRO D N   1 
ATOM   13943 C CA  . PRO D 1 398 ? -7.407  83.468  17.676 1.00 97.38  ? 406 PRO D CA  1 
ATOM   13944 C C   . PRO D 1 398 ? -6.028  83.399  18.321 1.00 99.27  ? 406 PRO D C   1 
ATOM   13945 O O   . PRO D 1 398 ? -5.326  84.422  18.386 1.00 87.86  ? 406 PRO D O   1 
ATOM   13946 C CB  . PRO D 1 398 ? -8.470  83.119  18.660 1.00 106.02 ? 406 PRO D CB  1 
ATOM   13947 C CG  . PRO D 1 398 ? -9.562  82.547  17.807 1.00 156.41 ? 406 PRO D CG  1 
ATOM   13948 C CD  . PRO D 1 398 ? -8.833  81.741  16.757 1.00 136.99 ? 406 PRO D CD  1 
ATOM   13949 N N   . ALA D 1 399 ? -5.622  82.178  18.713 1.00 74.17  ? 407 ALA D N   1 
ATOM   13950 C CA  . ALA D 1 399 ? -4.390  82.094  19.496 1.00 77.85  ? 407 ALA D CA  1 
ATOM   13951 C C   . ALA D 1 399 ? -3.195  82.662  18.738 1.00 85.72  ? 407 ALA D C   1 
ATOM   13952 O O   . ALA D 1 399 ? -2.511  83.565  19.237 1.00 80.70  ? 407 ALA D O   1 
ATOM   13953 C CB  . ALA D 1 399 ? -4.134  80.673  19.894 1.00 72.95  ? 407 ALA D CB  1 
ATOM   13954 N N   . LEU D 1 400 ? -2.959  82.115  17.519 1.00 100.01 ? 408 LEU D N   1 
ATOM   13955 C CA  . LEU D 1 400 ? -1.829  82.518  16.704 1.00 109.16 ? 408 LEU D CA  1 
ATOM   13956 C C   . LEU D 1 400 ? -1.954  83.989  16.324 1.00 104.52 ? 408 LEU D C   1 
ATOM   13957 O O   . LEU D 1 400 ? -0.934  84.660  16.236 1.00 80.12  ? 408 LEU D O   1 
ATOM   13958 C CB  . LEU D 1 400 ? -1.780  81.634  15.465 1.00 104.43 ? 408 LEU D CB  1 
ATOM   13959 C CG  . LEU D 1 400 ? -0.830  80.440  15.519 1.00 98.30  ? 408 LEU D CG  1 
ATOM   13960 C CD1 . LEU D 1 400 ? -0.707  79.794  14.162 1.00 115.05 ? 408 LEU D CD1 1 
ATOM   13961 C CD2 . LEU D 1 400 ? 0.545   80.736  16.102 1.00 73.97  ? 408 LEU D CD2 1 
ATOM   13962 N N   . THR D 1 401 ? -3.187  84.457  16.056 1.00 77.80  ? 409 THR D N   1 
ATOM   13963 C CA  . THR D 1 401 ? -3.376  85.825  15.611 1.00 75.07  ? 409 THR D CA  1 
ATOM   13964 C C   . THR D 1 401 ? -2.918  86.759  16.720 1.00 71.76  ? 409 THR D C   1 
ATOM   13965 O O   . THR D 1 401 ? -2.331  87.802  16.490 1.00 94.90  ? 409 THR D O   1 
ATOM   13966 C CB  . THR D 1 401 ? -4.803  86.120  15.141 1.00 82.21  ? 409 THR D CB  1 
ATOM   13967 O OG1 . THR D 1 401 ? -5.142  85.160  14.132 1.00 88.95  ? 409 THR D OG1 1 
ATOM   13968 C CG2 . THR D 1 401 ? -4.956  87.510  14.517 1.00 72.79  ? 409 THR D CG2 1 
ATOM   13969 N N   . SER D 1 402 ? -3.208  86.386  17.953 1.00 79.91  ? 410 SER D N   1 
ATOM   13970 C CA  . SER D 1 402 ? -2.817  87.205  19.085 1.00 77.45  ? 410 SER D CA  1 
ATOM   13971 C C   . SER D 1 402 ? -1.293  87.237  19.160 1.00 79.18  ? 410 SER D C   1 
ATOM   13972 O O   . SER D 1 402 ? -0.702  88.002  19.909 1.00 70.86  ? 410 SER D O   1 
ATOM   13973 C CB  . SER D 1 402 ? -3.397  86.615  20.355 1.00 82.31  ? 410 SER D CB  1 
ATOM   13974 O OG  . SER D 1 402 ? -4.819  86.734  20.414 1.00 68.48  ? 410 SER D OG  1 
ATOM   13975 N N   . ARG D 1 403 ? -0.644  86.334  18.418 1.00 79.35  ? 411 ARG D N   1 
ATOM   13976 C CA  . ARG D 1 403 ? 0.814   86.281  18.405 1.00 112.97 ? 411 ARG D CA  1 
ATOM   13977 C C   . ARG D 1 403 ? 1.334   87.236  17.321 1.00 110.13 ? 411 ARG D C   1 
ATOM   13978 O O   . ARG D 1 403 ? 2.485   87.688  17.340 1.00 100.75 ? 411 ARG D O   1 
ATOM   13979 C CB  . ARG D 1 403 ? 1.303   84.832  18.225 1.00 120.59 ? 411 ARG D CB  1 
ATOM   13980 C CG  . ARG D 1 403 ? 0.974   83.977  19.440 1.00 120.70 ? 411 ARG D CG  1 
ATOM   13981 C CD  . ARG D 1 403 ? 1.766   82.721  19.519 1.00 112.75 ? 411 ARG D CD  1 
ATOM   13982 N NE  . ARG D 1 403 ? 3.213   82.956  19.604 1.00 109.77 ? 411 ARG D NE  1 
ATOM   13983 C CZ  . ARG D 1 403 ? 4.076   81.947  19.732 1.00 102.64 ? 411 ARG D CZ  1 
ATOM   13984 N NH1 . ARG D 1 403 ? 3.636   80.692  19.720 1.00 94.11  ? 411 ARG D NH1 1 
ATOM   13985 N NH2 . ARG D 1 403 ? 5.370   82.200  19.863 1.00 82.05  ? 411 ARG D NH2 1 
ATOM   13986 N N   . GLY D 1 404 ? 0.468   87.571  16.368 1.00 80.01  ? 412 GLY D N   1 
ATOM   13987 C CA  . GLY D 1 404 ? 0.942   88.503  15.359 1.00 96.79  ? 412 GLY D CA  1 
ATOM   13988 C C   . GLY D 1 404 ? 0.754   87.988  13.936 1.00 99.66  ? 412 GLY D C   1 
ATOM   13989 O O   . GLY D 1 404 ? 0.723   88.792  13.006 1.00 113.12 ? 412 GLY D O   1 
ATOM   13990 N N   . LEU D 1 405 ? 0.539   86.676  13.788 1.00 90.30  ? 413 LEU D N   1 
ATOM   13991 C CA  . LEU D 1 405 ? 0.382   86.056  12.482 1.00 95.05  ? 413 LEU D CA  1 
ATOM   13992 C C   . LEU D 1 405 ? -0.676  86.769  11.634 1.00 110.95 ? 413 LEU D C   1 
ATOM   13993 O O   . LEU D 1 405 ? -1.767  87.117  12.120 1.00 79.79  ? 413 LEU D O   1 
ATOM   13994 C CB  . LEU D 1 405 ? 0.065   84.562  12.585 1.00 80.21  ? 413 LEU D CB  1 
ATOM   13995 C CG  . LEU D 1 405 ? 1.205   83.590  12.885 1.00 71.82  ? 413 LEU D CG  1 
ATOM   13996 C CD1 . LEU D 1 405 ? 1.618   83.569  14.335 1.00 85.97  ? 413 LEU D CD1 1 
ATOM   13997 C CD2 . LEU D 1 405 ? 0.651   82.266  12.514 1.00 70.58  ? 413 LEU D CD2 1 
ATOM   13998 N N   . LEU D 1 406 ? -0.340  86.946  10.336 1.00 99.92  ? 414 LEU D N   1 
ATOM   13999 C CA  . LEU D 1 406 ? -1.224  87.569  9.357  1.00 78.28  ? 414 LEU D CA  1 
ATOM   14000 C C   . LEU D 1 406 ? -1.475  86.566  8.231  1.00 104.28 ? 414 LEU D C   1 
ATOM   14001 O O   . LEU D 1 406 ? -1.102  85.387  8.370  1.00 124.44 ? 414 LEU D O   1 
ATOM   14002 C CB  . LEU D 1 406 ? -0.607  88.849  8.810  1.00 67.14  ? 414 LEU D CB  1 
ATOM   14003 C CG  . LEU D 1 406 ? -0.092  89.923  9.785  1.00 54.00  ? 414 LEU D CG  1 
ATOM   14004 C CD1 . LEU D 1 406 ? -0.098  91.176  8.905  1.00 59.69  ? 414 LEU D CD1 1 
ATOM   14005 C CD2 . LEU D 1 406 ? -0.834  90.278  11.081 1.00 49.27  ? 414 LEU D CD2 1 
ATOM   14006 N N   . GLU D 1 407 ? -2.089  87.022  7.113  1.00 84.93  ? 415 GLU D N   1 
ATOM   14007 C CA  . GLU D 1 407 ? -2.637  86.065  6.144  1.00 97.88  ? 415 GLU D CA  1 
ATOM   14008 C C   . GLU D 1 407 ? -1.535  85.169  5.571  1.00 98.80  ? 415 GLU D C   1 
ATOM   14009 O O   . GLU D 1 407 ? -1.684  83.937  5.513  1.00 108.04 ? 415 GLU D O   1 
ATOM   14010 C CB  . GLU D 1 407 ? -3.607  86.445  5.023  1.00 99.13  ? 415 GLU D CB  1 
ATOM   14011 C CG  . GLU D 1 407 ? -4.777  87.346  5.419  1.00 108.20 ? 415 GLU D CG  1 
ATOM   14012 C CD  . GLU D 1 407 ? -4.397  88.794  5.755  1.00 115.98 ? 415 GLU D CD  1 
ATOM   14013 O OE1 . GLU D 1 407 ? -3.219  89.078  6.184  1.00 85.47  ? 415 GLU D OE1 1 
ATOM   14014 O OE2 . GLU D 1 407 ? -5.268  89.673  5.517  1.00 83.32  ? 415 GLU D OE2 1 
ATOM   14015 N N   . LYS D 1 408 ? -0.420  85.783  5.151  1.00 112.07 ? 416 LYS D N   1 
ATOM   14016 C CA  . LYS D 1 408 ? 0.652   85.006  4.537  1.00 106.07 ? 416 LYS D CA  1 
ATOM   14017 C C   . LYS D 1 408 ? 1.107   83.944  5.529  1.00 98.91  ? 416 LYS D C   1 
ATOM   14018 O O   . LYS D 1 408 ? 1.273   82.801  5.127  1.00 100.95 ? 416 LYS D O   1 
ATOM   14019 C CB  . LYS D 1 408 ? 1.726   85.784  3.758  1.00 104.11 ? 416 LYS D CB  1 
ATOM   14020 C CG  . LYS D 1 408 ? 2.367   87.049  4.393  1.00 102.26 ? 416 LYS D CG  1 
ATOM   14021 C CD  . LYS D 1 408 ? 2.587   88.208  3.418  1.00 119.08 ? 416 LYS D CD  1 
ATOM   14022 C CE  . LYS D 1 408 ? 3.615   89.247  3.814  1.00 120.96 ? 416 LYS D CE  1 
ATOM   14023 N NZ  . LYS D 1 408 ? 4.983   88.815  3.494  1.00 110.90 ? 416 LYS D NZ  1 
ATOM   14024 N N   . ASP D 1 409 ? 1.268   84.336  6.806  1.00 82.78  ? 417 ASP D N   1 
ATOM   14025 C CA  . ASP D 1 409 ? 1.713   83.439  7.868  1.00 90.79  ? 417 ASP D CA  1 
ATOM   14026 C C   . ASP D 1 409 ? 0.784   82.236  8.009  1.00 109.21 ? 417 ASP D C   1 
ATOM   14027 O O   . ASP D 1 409 ? 1.254   81.104  8.128  1.00 96.66  ? 417 ASP D O   1 
ATOM   14028 C CB  . ASP D 1 409 ? 1.826   84.180  9.176  1.00 83.03  ? 417 ASP D CB  1 
ATOM   14029 C CG  . ASP D 1 409 ? 2.823   85.318  9.125  1.00 110.99 ? 417 ASP D CG  1 
ATOM   14030 O OD1 . ASP D 1 409 ? 3.943   85.071  8.643  1.00 123.47 ? 417 ASP D OD1 1 
ATOM   14031 O OD2 . ASP D 1 409 ? 2.491   86.413  9.603  1.00 120.81 ? 417 ASP D OD2 1 
ATOM   14032 N N   . PHE D 1 410 ? -0.526  82.501  7.984  1.00 111.53 ? 418 PHE D N   1 
ATOM   14033 C CA  . PHE D 1 410 ? -1.532  81.450  8.100  1.00 131.22 ? 418 PHE D CA  1 
ATOM   14034 C C   . PHE D 1 410 ? -1.454  80.481  6.922  1.00 150.18 ? 418 PHE D C   1 
ATOM   14035 O O   . PHE D 1 410 ? -1.942  79.349  7.008  1.00 159.65 ? 418 PHE D O   1 
ATOM   14036 C CB  . PHE D 1 410 ? -2.979  81.943  8.276  1.00 97.96  ? 418 PHE D CB  1 
ATOM   14037 C CG  . PHE D 1 410 ? -3.308  81.901  9.757  1.00 95.39  ? 418 PHE D CG  1 
ATOM   14038 C CD1 . PHE D 1 410 ? -3.700  80.709  10.350 1.00 93.03  ? 418 PHE D CD1 1 
ATOM   14039 C CD2 . PHE D 1 410 ? -3.081  83.006  10.577 1.00 117.88 ? 418 PHE D CD2 1 
ATOM   14040 C CE1 . PHE D 1 410 ? -3.840  80.628  11.719 1.00 105.76 ? 418 PHE D CE1 1 
ATOM   14041 C CE2 . PHE D 1 410 ? -3.289  82.942  11.942 1.00 120.64 ? 418 PHE D CE2 1 
ATOM   14042 C CZ  . PHE D 1 410 ? -3.651  81.747  12.502 1.00 123.37 ? 418 PHE D CZ  1 
ATOM   14043 N N   . GLN D 1 411 ? -0.883  80.954  5.812  1.00 143.60 ? 419 GLN D N   1 
ATOM   14044 C CA  . GLN D 1 411 ? -0.810  80.102  4.640  1.00 122.20 ? 419 GLN D CA  1 
ATOM   14045 C C   . GLN D 1 411 ? 0.321   79.109  4.893  1.00 111.00 ? 419 GLN D C   1 
ATOM   14046 O O   . GLN D 1 411 ? 0.229   77.933  4.526  1.00 112.11 ? 419 GLN D O   1 
ATOM   14047 C CB  . GLN D 1 411 ? -0.695  80.907  3.342  1.00 128.40 ? 419 GLN D CB  1 
ATOM   14048 C CG  . GLN D 1 411 ? -1.687  82.056  3.269  1.00 165.61 ? 419 GLN D CG  1 
ATOM   14049 C CD  . GLN D 1 411 ? -2.215  82.274  1.876  1.00 138.15 ? 419 GLN D CD  1 
ATOM   14050 O OE1 . GLN D 1 411 ? -2.801  81.355  1.296  1.00 116.49 ? 419 GLN D OE1 1 
ATOM   14051 N NE2 . GLN D 1 411 ? -2.017  83.478  1.357  1.00 149.20 ? 419 GLN D NE2 1 
ATOM   14052 N N   . LYS D 1 412 ? 1.376   79.606  5.552  1.00 81.11  ? 420 LYS D N   1 
ATOM   14053 C CA  . LYS D 1 412 ? 2.560   78.809  5.800  1.00 80.16  ? 420 LYS D CA  1 
ATOM   14054 C C   . LYS D 1 412 ? 2.100   77.731  6.774  1.00 101.94 ? 420 LYS D C   1 
ATOM   14055 O O   . LYS D 1 412 ? 2.580   76.597  6.755  1.00 117.02 ? 420 LYS D O   1 
ATOM   14056 C CB  . LYS D 1 412 ? 3.696   79.712  6.303  1.00 73.90  ? 420 LYS D CB  1 
ATOM   14057 C CG  . LYS D 1 412 ? 4.986   79.016  6.712  1.00 80.33  ? 420 LYS D CG  1 
ATOM   14058 C CD  . LYS D 1 412 ? 6.174   79.968  6.899  1.00 84.20  ? 420 LYS D CD  1 
ATOM   14059 C CE  . LYS D 1 412 ? 7.522   79.279  6.719  1.00 80.81  ? 420 LYS D CE  1 
ATOM   14060 N NZ  . LYS D 1 412 ? 8.635   79.886  7.461  1.00 77.78  ? 420 LYS D NZ  1 
ATOM   14061 N N   . VAL D 1 413 ? 1.140   78.107  7.629  1.00 90.39  ? 421 VAL D N   1 
ATOM   14062 C CA  . VAL D 1 413 ? 0.653   77.206  8.656  1.00 95.62  ? 421 VAL D CA  1 
ATOM   14063 C C   . VAL D 1 413 ? -0.084  76.066  7.979  1.00 90.83  ? 421 VAL D C   1 
ATOM   14064 O O   . VAL D 1 413 ? 0.165   74.899  8.295  1.00 86.46  ? 421 VAL D O   1 
ATOM   14065 C CB  . VAL D 1 413 ? -0.198  77.941  9.698  1.00 82.58  ? 421 VAL D CB  1 
ATOM   14066 C CG1 . VAL D 1 413 ? -0.859  76.965  10.651 1.00 78.89  ? 421 VAL D CG1 1 
ATOM   14067 C CG2 . VAL D 1 413 ? 0.682   78.914  10.480 1.00 72.22  ? 421 VAL D CG2 1 
ATOM   14068 N N   . ALA D 1 414 ? -0.947  76.436  7.027  1.00 87.06  ? 422 ALA D N   1 
ATOM   14069 C CA  . ALA D 1 414 ? -1.730  75.467  6.271  1.00 88.93  ? 422 ALA D CA  1 
ATOM   14070 C C   . ALA D 1 414 ? -0.797  74.441  5.643  1.00 94.77  ? 422 ALA D C   1 
ATOM   14071 O O   . ALA D 1 414 ? -1.118  73.255  5.600  1.00 86.23  ? 422 ALA D O   1 
ATOM   14072 C CB  . ALA D 1 414 ? -2.543  76.172  5.207  1.00 100.31 ? 422 ALA D CB  1 
ATOM   14073 N N   . HIS D 1 415 ? 0.390   74.896  5.224  1.00 103.15 ? 423 HIS D N   1 
ATOM   14074 C CA  . HIS D 1 415 ? 1.354   74.007  4.600  1.00 111.25 ? 423 HIS D CA  1 
ATOM   14075 C C   . HIS D 1 415 ? 1.950   73.060  5.654  1.00 112.02 ? 423 HIS D C   1 
ATOM   14076 O O   . HIS D 1 415 ? 2.170   71.869  5.371  1.00 89.18  ? 423 HIS D O   1 
ATOM   14077 C CB  . HIS D 1 415 ? 2.437   74.801  3.851  1.00 90.69  ? 423 HIS D CB  1 
ATOM   14078 C CG  . HIS D 1 415 ? 2.035   75.712  2.742  1.00 86.04  ? 423 HIS D CG  1 
ATOM   14079 N ND1 . HIS D 1 415 ? 1.068   75.483  1.768  1.00 102.55 ? 423 HIS D ND1 1 
ATOM   14080 C CD2 . HIS D 1 415 ? 2.629   76.868  2.436  1.00 72.96  ? 423 HIS D CD2 1 
ATOM   14081 C CE1 . HIS D 1 415 ? 1.031   76.505  0.912  1.00 66.25  ? 423 HIS D CE1 1 
ATOM   14082 N NE2 . HIS D 1 415 ? 1.984   77.357  1.303  1.00 82.75  ? 423 HIS D NE2 1 
ATOM   14083 N N   . PHE D 1 416 ? 2.222   73.606  6.855  1.00 87.76  ? 424 PHE D N   1 
ATOM   14084 C CA  . PHE D 1 416 ? 2.778   72.773  7.908  1.00 106.42 ? 424 PHE D CA  1 
ATOM   14085 C C   . PHE D 1 416 ? 1.755   71.714  8.331  1.00 99.09  ? 424 PHE D C   1 
ATOM   14086 O O   . PHE D 1 416 ? 2.076   70.534  8.487  1.00 80.00  ? 424 PHE D O   1 
ATOM   14087 C CB  . PHE D 1 416 ? 3.313   73.612  9.059  1.00 99.88  ? 424 PHE D CB  1 
ATOM   14088 C CG  . PHE D 1 416 ? 4.584   74.386  8.752  1.00 109.96 ? 424 PHE D CG  1 
ATOM   14089 C CD1 . PHE D 1 416 ? 5.402   74.048  7.675  1.00 98.29  ? 424 PHE D CD1 1 
ATOM   14090 C CD2 . PHE D 1 416 ? 4.864   75.553  9.460  1.00 132.31 ? 424 PHE D CD2 1 
ATOM   14091 C CE1 . PHE D 1 416 ? 6.503   74.836  7.376  1.00 143.12 ? 424 PHE D CE1 1 
ATOM   14092 C CE2 . PHE D 1 416 ? 5.980   76.321  9.180  1.00 135.65 ? 424 PHE D CE2 1 
ATOM   14093 C CZ  . PHE D 1 416 ? 6.795   75.954  8.139  1.00 172.55 ? 424 PHE D CZ  1 
ATOM   14094 N N   . ILE D 1 417 ? 0.497   72.136  8.445  1.00 89.99  ? 425 ILE D N   1 
ATOM   14095 C CA  . ILE D 1 417 ? -0.596  71.208  8.688  1.00 103.16 ? 425 ILE D CA  1 
ATOM   14096 C C   . ILE D 1 417 ? -0.588  70.126  7.611  1.00 100.00 ? 425 ILE D C   1 
ATOM   14097 O O   . ILE D 1 417 ? -0.675  68.943  7.949  1.00 99.07  ? 425 ILE D O   1 
ATOM   14098 C CB  . ILE D 1 417 ? -1.952  71.939  8.751  1.00 101.24 ? 425 ILE D CB  1 
ATOM   14099 C CG1 . ILE D 1 417 ? -2.057  72.864  9.993  1.00 89.95  ? 425 ILE D CG1 1 
ATOM   14100 C CG2 . ILE D 1 417 ? -3.120  70.943  8.593  1.00 58.38  ? 425 ILE D CG2 1 
ATOM   14101 C CD1 . ILE D 1 417 ? -3.175  73.895  9.851  1.00 88.42  ? 425 ILE D CD1 1 
ATOM   14102 N N   . HIS D 1 418 ? -0.431  70.542  6.339  1.00 80.75  ? 426 HIS D N   1 
ATOM   14103 C CA  . HIS D 1 418 ? -0.467  69.578  5.256  1.00 91.83  ? 426 HIS D CA  1 
ATOM   14104 C C   . HIS D 1 418 ? 0.594   68.498  5.483  1.00 98.14  ? 426 HIS D C   1 
ATOM   14105 O O   . HIS D 1 418 ? 0.286   67.302  5.466  1.00 92.49  ? 426 HIS D O   1 
ATOM   14106 C CB  . HIS D 1 418 ? -0.410  70.177  3.840  1.00 86.93  ? 426 HIS D CB  1 
ATOM   14107 C CG  . HIS D 1 418 ? -0.348  69.039  2.843  1.00 91.04  ? 426 HIS D CG  1 
ATOM   14108 N ND1 . HIS D 1 418 ? -1.395  68.134  2.735  1.00 87.72  ? 426 HIS D ND1 1 
ATOM   14109 C CD2 . HIS D 1 418 ? 0.622   68.551  2.021  1.00 73.94  ? 426 HIS D CD2 1 
ATOM   14110 C CE1 . HIS D 1 418 ? -1.098  67.175  1.844  1.00 74.88  ? 426 HIS D CE1 1 
ATOM   14111 N NE2 . HIS D 1 418 ? 0.132   67.403  1.417  1.00 80.49  ? 426 HIS D NE2 1 
ATOM   14112 N N   . ARG D 1 419 ? 1.842   68.922  5.715  1.00 75.27  ? 427 ARG D N   1 
ATOM   14113 C CA  . ARG D 1 419 ? 2.896   67.954  6.007  1.00 94.26  ? 427 ARG D CA  1 
ATOM   14114 C C   . ARG D 1 419 ? 2.469   67.003  7.144  1.00 105.13 ? 427 ARG D C   1 
ATOM   14115 O O   . ARG D 1 419 ? 2.585   65.776  7.040  1.00 76.84  ? 427 ARG D O   1 
ATOM   14116 C CB  . ARG D 1 419 ? 4.200   68.700  6.325  1.00 75.67  ? 427 ARG D CB  1 
ATOM   14117 C CG  . ARG D 1 419 ? 4.401   69.912  5.426  1.00 77.97  ? 427 ARG D CG  1 
ATOM   14118 C CD  . ARG D 1 419 ? 5.767   70.173  4.796  1.00 85.04  ? 427 ARG D CD  1 
ATOM   14119 N NE  . ARG D 1 419 ? 6.614   71.158  5.469  1.00 96.14  ? 427 ARG D NE  1 
ATOM   14120 C CZ  . ARG D 1 419 ? 7.856   70.915  5.882  1.00 107.81 ? 427 ARG D CZ  1 
ATOM   14121 N NH1 . ARG D 1 419 ? 8.317   69.662  5.859  1.00 98.72  ? 427 ARG D NH1 1 
ATOM   14122 N NH2 . ARG D 1 419 ? 8.594   71.905  6.377  1.00 73.61  ? 427 ARG D NH2 1 
ATOM   14123 N N   . GLY D 1 420 ? 1.991   67.585  8.252  1.00 84.54  ? 428 GLY D N   1 
ATOM   14124 C CA  . GLY D 1 420 ? 1.373   66.782  9.287  1.00 79.11  ? 428 GLY D CA  1 
ATOM   14125 C C   . GLY D 1 420 ? 0.441   65.690  8.732  1.00 77.61  ? 428 GLY D C   1 
ATOM   14126 O O   . GLY D 1 420 ? 0.530   64.536  9.137  1.00 95.99  ? 428 GLY D O   1 
ATOM   14127 N N   . ILE D 1 421 ? -0.483  66.045  7.830  1.00 50.71  ? 429 ILE D N   1 
ATOM   14128 C CA  . ILE D 1 421 ? -1.455  65.108  7.291  1.00 72.33  ? 429 ILE D CA  1 
ATOM   14129 C C   . ILE D 1 421 ? -0.771  64.010  6.476  1.00 88.91  ? 429 ILE D C   1 
ATOM   14130 O O   . ILE D 1 421 ? -1.215  62.853  6.497  1.00 90.89  ? 429 ILE D O   1 
ATOM   14131 C CB  . ILE D 1 421 ? -2.528  65.861  6.477  1.00 83.41  ? 429 ILE D CB  1 
ATOM   14132 C CG1 . ILE D 1 421 ? -3.241  66.905  7.338  1.00 91.49  ? 429 ILE D CG1 1 
ATOM   14133 C CG2 . ILE D 1 421 ? -3.503  64.892  5.777  1.00 90.29  ? 429 ILE D CG2 1 
ATOM   14134 C CD1 . ILE D 1 421 ? -3.810  66.374  8.644  1.00 110.80 ? 429 ILE D CD1 1 
ATOM   14135 N N   . GLU D 1 422 ? 0.281   64.401  5.737  1.00 89.67  ? 430 GLU D N   1 
ATOM   14136 C CA  . GLU D 1 422 ? 1.030   63.469  4.907  1.00 84.36  ? 430 GLU D CA  1 
ATOM   14137 C C   . GLU D 1 422 ? 1.604   62.387  5.826  1.00 79.81  ? 430 GLU D C   1 
ATOM   14138 O O   . GLU D 1 422 ? 1.476   61.180  5.530  1.00 47.07  ? 430 GLU D O   1 
ATOM   14139 C CB  . GLU D 1 422 ? 2.173   64.137  4.129  1.00 70.44  ? 430 GLU D CB  1 
ATOM   14140 C CG  . GLU D 1 422 ? 1.744   65.133  3.067  1.00 90.27  ? 430 GLU D CG  1 
ATOM   14141 C CD  . GLU D 1 422 ? 2.871   65.567  2.152  1.00 97.71  ? 430 GLU D CD  1 
ATOM   14142 O OE1 . GLU D 1 422 ? 3.980   65.649  2.744  1.00 103.48 ? 430 GLU D OE1 1 
ATOM   14143 O OE2 . GLU D 1 422 ? 2.656   65.855  0.927  1.00 78.45  ? 430 GLU D OE2 1 
ATOM   14144 N N   . LEU D 1 423 ? 2.220   62.856  6.939  1.00 61.94  ? 431 LEU D N   1 
ATOM   14145 C CA  . LEU D 1 423 ? 2.825   61.962  7.907  1.00 80.04  ? 431 LEU D CA  1 
ATOM   14146 C C   . LEU D 1 423 ? 1.749   61.023  8.441  1.00 94.41  ? 431 LEU D C   1 
ATOM   14147 O O   . LEU D 1 423 ? 1.913   59.799  8.419  1.00 92.53  ? 431 LEU D O   1 
ATOM   14148 C CB  . LEU D 1 423 ? 3.473   62.765  9.027  1.00 65.90  ? 431 LEU D CB  1 
ATOM   14149 C CG  . LEU D 1 423 ? 4.987   62.874  8.918  1.00 71.84  ? 431 LEU D CG  1 
ATOM   14150 C CD1 . LEU D 1 423 ? 5.604   63.728  10.015 1.00 78.66  ? 431 LEU D CD1 1 
ATOM   14151 C CD2 . LEU D 1 423 ? 5.480   61.422  9.015  1.00 83.74  ? 431 LEU D CD2 1 
ATOM   14152 N N   . THR D 1 424 ? 0.614   61.624  8.814  1.00 66.61  ? 432 THR D N   1 
ATOM   14153 C CA  . THR D 1 424 ? -0.500  60.848  9.324  1.00 75.45  ? 432 THR D CA  1 
ATOM   14154 C C   . THR D 1 424 ? -0.813  59.697  8.362  1.00 80.61  ? 432 THR D C   1 
ATOM   14155 O O   . THR D 1 424 ? -1.003  58.534  8.762  1.00 69.36  ? 432 THR D O   1 
ATOM   14156 C CB  . THR D 1 424 ? -1.683  61.800  9.485  1.00 85.04  ? 432 THR D CB  1 
ATOM   14157 O OG1 . THR D 1 424 ? -0.981  62.626  10.410 1.00 100.75 ? 432 THR D OG1 1 
ATOM   14158 C CG2 . THR D 1 424 ? -2.896  61.159  10.135 1.00 71.81  ? 432 THR D CG2 1 
ATOM   14159 N N   . LEU D 1 425 ? -0.851  60.039  7.067  1.00 63.53  ? 433 LEU D N   1 
ATOM   14160 C CA  . LEU D 1 425 ? -1.235  59.119  6.020  1.00 65.00  ? 433 LEU D CA  1 
ATOM   14161 C C   . LEU D 1 425 ? -0.219  57.972  5.930  1.00 93.13  ? 433 LEU D C   1 
ATOM   14162 O O   . LEU D 1 425 ? -0.585  56.785  5.753  1.00 104.91 ? 433 LEU D O   1 
ATOM   14163 C CB  . LEU D 1 425 ? -1.277  60.034  4.792  1.00 49.79  ? 433 LEU D CB  1 
ATOM   14164 C CG  . LEU D 1 425 ? -2.663  60.245  4.167  1.00 64.21  ? 433 LEU D CG  1 
ATOM   14165 C CD1 . LEU D 1 425 ? -2.889  61.694  3.688  1.00 60.46  ? 433 LEU D CD1 1 
ATOM   14166 C CD2 . LEU D 1 425 ? -3.020  59.185  3.081  1.00 54.90  ? 433 LEU D CD2 1 
ATOM   14167 N N   . GLN D 1 426 ? 1.066   58.372  6.012  1.00 79.20  ? 434 GLN D N   1 
ATOM   14168 C CA  . GLN D 1 426 ? 2.163   57.436  5.893  1.00 83.43  ? 434 GLN D CA  1 
ATOM   14169 C C   . GLN D 1 426 ? 1.964   56.409  6.979  1.00 94.11  ? 434 GLN D C   1 
ATOM   14170 O O   . GLN D 1 426 ? 1.522   55.307  6.646  1.00 58.72  ? 434 GLN D O   1 
ATOM   14171 C CB  . GLN D 1 426 ? 3.485   58.189  5.879  1.00 69.68  ? 434 GLN D CB  1 
ATOM   14172 C CG  . GLN D 1 426 ? 3.677   58.759  4.482  1.00 74.26  ? 434 GLN D CG  1 
ATOM   14173 C CD  . GLN D 1 426 ? 4.818   59.723  4.391  1.00 78.93  ? 434 GLN D CD  1 
ATOM   14174 O OE1 . GLN D 1 426 ? 5.442   60.056  5.419  1.00 64.98  ? 434 GLN D OE1 1 
ATOM   14175 N NE2 . GLN D 1 426 ? 4.991   60.187  3.152  1.00 64.15  ? 434 GLN D NE2 1 
ATOM   14176 N N   . ILE D 1 427 ? 1.942   56.902  8.214  1.00 90.31  ? 435 ILE D N   1 
ATOM   14177 C CA  . ILE D 1 427 ? 1.788   56.014  9.346  1.00 83.81  ? 435 ILE D CA  1 
ATOM   14178 C C   . ILE D 1 427 ? 0.611   55.065  9.145  1.00 87.96  ? 435 ILE D C   1 
ATOM   14179 O O   . ILE D 1 427 ? 0.881   53.875  9.047  1.00 97.50  ? 435 ILE D O   1 
ATOM   14180 C CB  . ILE D 1 427 ? 1.687   56.853  10.616 1.00 82.86  ? 435 ILE D CB  1 
ATOM   14181 C CG1 . ILE D 1 427 ? 2.832   57.882  10.634 1.00 78.60  ? 435 ILE D CG1 1 
ATOM   14182 C CG2 . ILE D 1 427 ? 1.615   55.963  11.859 1.00 92.67  ? 435 ILE D CG2 1 
ATOM   14183 C CD1 . ILE D 1 427 ? 2.519   59.167  11.414 1.00 87.69  ? 435 ILE D CD1 1 
ATOM   14184 N N   . GLN D 1 428 ? -0.591  55.599  8.847  1.00 78.68  ? 436 GLN D N   1 
ATOM   14185 C CA  . GLN D 1 428 ? -1.812  54.840  8.633  1.00 95.78  ? 436 GLN D CA  1 
ATOM   14186 C C   . GLN D 1 428 ? -1.640  53.699  7.630  1.00 111.28 ? 436 GLN D C   1 
ATOM   14187 O O   . GLN D 1 428 ? -2.201  52.621  7.837  1.00 112.93 ? 436 GLN D O   1 
ATOM   14188 C CB  . GLN D 1 428 ? -2.843  55.886  8.228  1.00 103.08 ? 436 GLN D CB  1 
ATOM   14189 C CG  . GLN D 1 428 ? -4.146  55.445  7.572  1.00 125.36 ? 436 GLN D CG  1 
ATOM   14190 C CD  . GLN D 1 428 ? -5.073  56.643  7.565  1.00 132.52 ? 436 GLN D CD  1 
ATOM   14191 O OE1 . GLN D 1 428 ? -4.625  57.780  7.707  1.00 167.74 ? 436 GLN D OE1 1 
ATOM   14192 N NE2 . GLN D 1 428 ? -6.365  56.430  7.454  1.00 106.74 ? 436 GLN D NE2 1 
ATOM   14193 N N   . SER D 1 429 ? -0.873  53.937  6.556  1.00 117.86 ? 437 SER D N   1 
ATOM   14194 C CA  . SER D 1 429 ? -0.745  52.949  5.500  1.00 114.59 ? 437 SER D CA  1 
ATOM   14195 C C   . SER D 1 429 ? 0.133   51.773  5.921  1.00 101.77 ? 437 SER D C   1 
ATOM   14196 O O   . SER D 1 429 ? -0.075  50.667  5.457  1.00 138.15 ? 437 SER D O   1 
ATOM   14197 C CB  . SER D 1 429 ? -0.255  53.550  4.230  1.00 110.47 ? 437 SER D CB  1 
ATOM   14198 O OG  . SER D 1 429 ? 1.083   53.976  4.423  1.00 102.50 ? 437 SER D OG  1 
ATOM   14199 N N   . ASP D 1 430 ? 1.119   52.032  6.779  1.00 91.92  ? 438 ASP D N   1 
ATOM   14200 C CA  . ASP D 1 430 ? 1.950   50.993  7.386  1.00 99.25  ? 438 ASP D CA  1 
ATOM   14201 C C   . ASP D 1 430 ? 1.210   50.392  8.563  1.00 124.84 ? 438 ASP D C   1 
ATOM   14202 O O   . ASP D 1 430 ? 1.464   49.257  8.954  1.00 142.97 ? 438 ASP D O   1 
ATOM   14203 C CB  . ASP D 1 430 ? 3.232   51.579  7.940  1.00 76.68  ? 438 ASP D CB  1 
ATOM   14204 C CG  . ASP D 1 430 ? 3.936   52.461  6.924  1.00 111.53 ? 438 ASP D CG  1 
ATOM   14205 O OD1 . ASP D 1 430 ? 3.417   52.579  5.741  1.00 90.24  ? 438 ASP D OD1 1 
ATOM   14206 O OD2 . ASP D 1 430 ? 4.999   53.001  7.304  1.00 110.76 ? 438 ASP D OD2 1 
ATOM   14207 N N   . THR D 1 431 ? 0.324   51.199  9.141  1.00 143.51 ? 439 THR D N   1 
ATOM   14208 C CA  . THR D 1 431 ? -0.497  50.765  10.257 1.00 109.61 ? 439 THR D CA  1 
ATOM   14209 C C   . THR D 1 431 ? -1.249  49.504  9.853  1.00 95.76  ? 439 THR D C   1 
ATOM   14210 O O   . THR D 1 431 ? -1.476  48.649  10.704 1.00 80.41  ? 439 THR D O   1 
ATOM   14211 C CB  . THR D 1 431 ? -1.344  51.949  10.715 1.00 143.36 ? 439 THR D CB  1 
ATOM   14212 O OG1 . THR D 1 431 ? -0.667  52.371  11.900 1.00 136.42 ? 439 THR D OG1 1 
ATOM   14213 C CG2 . THR D 1 431 ? -2.841  51.735  10.886 1.00 142.74 ? 439 THR D CG2 1 
ATOM   14214 N N   . GLY D 1 432 ? -1.408  49.308  8.535  1.00 95.08  ? 440 GLY D N   1 
ATOM   14215 C CA  . GLY D 1 432 ? -2.203  48.219  7.987  1.00 113.96 ? 440 GLY D CA  1 
ATOM   14216 C C   . GLY D 1 432 ? -3.594  48.726  7.627  1.00 131.98 ? 440 GLY D C   1 
ATOM   14217 O O   . GLY D 1 432 ? -4.012  49.798  8.078  1.00 105.66 ? 440 GLY D O   1 
ATOM   14218 N N   . VAL D 1 433 ? -4.290  47.913  6.810  1.00 154.60 ? 441 VAL D N   1 
ATOM   14219 C CA  . VAL D 1 433 ? -5.455  48.311  6.020  1.00 165.02 ? 441 VAL D CA  1 
ATOM   14220 C C   . VAL D 1 433 ? -6.597  48.791  6.951  1.00 173.82 ? 441 VAL D C   1 
ATOM   14221 O O   . VAL D 1 433 ? -7.414  49.607  6.519  1.00 182.97 ? 441 VAL D O   1 
ATOM   14222 C CB  . VAL D 1 433 ? -5.784  47.248  4.922  1.00 136.95 ? 441 VAL D CB  1 
ATOM   14223 C CG1 . VAL D 1 433 ? -6.263  47.785  3.554  1.00 94.94  ? 441 VAL D CG1 1 
ATOM   14224 C CG2 . VAL D 1 433 ? -4.557  46.373  4.648  1.00 121.65 ? 441 VAL D CG2 1 
ATOM   14225 N N   . ALA D 1 434 ? -6.661  48.347  8.225  1.00 151.98 ? 442 ALA D N   1 
ATOM   14226 C CA  . ALA D 1 434 ? -7.597  48.912  9.208  1.00 124.70 ? 442 ALA D CA  1 
ATOM   14227 C C   . ALA D 1 434 ? -7.107  48.700  10.648 1.00 133.92 ? 442 ALA D C   1 
ATOM   14228 O O   . ALA D 1 434 ? -7.835  48.230  11.532 1.00 140.24 ? 442 ALA D O   1 
ATOM   14229 C CB  . ALA D 1 434 ? -8.980  48.306  9.026  1.00 30.00  ? 442 ALA D CB  1 
ATOM   14230 N N   . ALA D 1 435 ? -5.864  49.134  10.892 1.00 128.80 ? 443 ALA D N   1 
ATOM   14231 C CA  . ALA D 1 435 ? -5.255  49.195  12.221 1.00 131.03 ? 443 ALA D CA  1 
ATOM   14232 C C   . ALA D 1 435 ? -6.059  50.055  13.199 1.00 106.77 ? 443 ALA D C   1 
ATOM   14233 O O   . ALA D 1 435 ? -6.610  51.087  12.833 1.00 105.14 ? 443 ALA D O   1 
ATOM   14234 C CB  . ALA D 1 435 ? -3.851  49.730  12.107 1.00 144.17 ? 443 ALA D CB  1 
ATOM   14235 N N   . THR D 1 436 ? -6.071  49.650  14.468 1.00 98.65  ? 444 THR D N   1 
ATOM   14236 C CA  . THR D 1 436 ? -6.582  50.442  15.596 1.00 125.17 ? 444 THR D CA  1 
ATOM   14237 C C   . THR D 1 436 ? -5.841  51.774  15.828 1.00 137.54 ? 444 THR D C   1 
ATOM   14238 O O   . THR D 1 436 ? -4.695  51.960  15.406 1.00 133.09 ? 444 THR D O   1 
ATOM   14239 C CB  . THR D 1 436 ? -6.602  49.632  16.900 1.00 109.48 ? 444 THR D CB  1 
ATOM   14240 O OG1 . THR D 1 436 ? -5.250  49.275  17.191 1.00 150.01 ? 444 THR D OG1 1 
ATOM   14241 C CG2 . THR D 1 436 ? -7.510  48.418  16.873 1.00 119.06 ? 444 THR D CG2 1 
ATOM   14242 N N   . LEU D 1 437 ? -6.512  52.684  16.556 1.00 129.93 ? 445 LEU D N   1 
ATOM   14243 C CA  . LEU D 1 437 ? -5.885  53.938  16.935 1.00 102.83 ? 445 LEU D CA  1 
ATOM   14244 C C   . LEU D 1 437 ? -4.650  53.632  17.784 1.00 100.72 ? 445 LEU D C   1 
ATOM   14245 O O   . LEU D 1 437 ? -3.715  54.456  17.861 1.00 99.76  ? 445 LEU D O   1 
ATOM   14246 C CB  . LEU D 1 437 ? -6.812  54.928  17.650 1.00 68.48  ? 445 LEU D CB  1 
ATOM   14247 C CG  . LEU D 1 437 ? -6.118  56.259  18.010 1.00 57.03  ? 445 LEU D CG  1 
ATOM   14248 C CD1 . LEU D 1 437 ? -5.884  57.068  16.732 1.00 65.65  ? 445 LEU D CD1 1 
ATOM   14249 C CD2 . LEU D 1 437 ? -6.725  57.152  19.093 1.00 68.11  ? 445 LEU D CD2 1 
ATOM   14250 N N   . LYS D 1 438 ? -4.702  52.461  18.456 1.00 84.78  ? 446 LYS D N   1 
ATOM   14251 C CA  . LYS D 1 438 ? -3.709  51.989  19.406 1.00 96.60  ? 446 LYS D CA  1 
ATOM   14252 C C   . LYS D 1 438 ? -2.423  51.728  18.619 1.00 107.88 ? 446 LYS D C   1 
ATOM   14253 O O   . LYS D 1 438 ? -1.392  52.345  18.908 1.00 123.32 ? 446 LYS D O   1 
ATOM   14254 C CB  . LYS D 1 438 ? -4.390  50.845  20.184 1.00 120.05 ? 446 LYS D CB  1 
ATOM   14255 C CG  . LYS D 1 438 ? -3.572  49.797  20.962 1.00 142.71 ? 446 LYS D CG  1 
ATOM   14256 C CD  . LYS D 1 438 ? -3.916  48.310  20.789 1.00 106.23 ? 446 LYS D CD  1 
ATOM   14257 C CE  . LYS D 1 438 ? -2.677  47.463  20.959 1.00 92.74  ? 446 LYS D CE  1 
ATOM   14258 N NZ  . LYS D 1 438 ? -2.987  46.039  20.923 1.00 93.99  ? 446 LYS D NZ  1 
ATOM   14259 N N   . GLU D 1 439 ? -2.536  50.849  17.605 1.00 124.14 ? 447 GLU D N   1 
ATOM   14260 C CA  . GLU D 1 439 ? -1.451  50.476  16.712 1.00 103.64 ? 447 GLU D CA  1 
ATOM   14261 C C   . GLU D 1 439 ? -0.888  51.725  16.039 1.00 97.10  ? 447 GLU D C   1 
ATOM   14262 O O   . GLU D 1 439 ? 0.333   51.842  15.922 1.00 72.26  ? 447 GLU D O   1 
ATOM   14263 C CB  . GLU D 1 439 ? -1.925  49.486  15.650 1.00 94.13  ? 447 GLU D CB  1 
ATOM   14264 C CG  . GLU D 1 439 ? -2.173  48.067  16.156 1.00 121.95 ? 447 GLU D CG  1 
ATOM   14265 C CD  . GLU D 1 439 ? -3.149  47.324  15.256 1.00 147.66 ? 447 GLU D CD  1 
ATOM   14266 O OE1 . GLU D 1 439 ? -2.744  46.472  14.443 1.00 155.15 ? 447 GLU D OE1 1 
ATOM   14267 O OE2 . GLU D 1 439 ? -4.355  47.645  15.323 1.00 179.54 ? 447 GLU D OE2 1 
ATOM   14268 N N   . PHE D 1 440 ? -1.762  52.623  15.560 1.00 80.15  ? 448 PHE D N   1 
ATOM   14269 C CA  . PHE D 1 440 ? -1.343  53.914  15.027 1.00 86.42  ? 448 PHE D CA  1 
ATOM   14270 C C   . PHE D 1 440 ? -0.395  54.680  15.972 1.00 91.60  ? 448 PHE D C   1 
ATOM   14271 O O   . PHE D 1 440 ? 0.650   55.151  15.529 1.00 86.76  ? 448 PHE D O   1 
ATOM   14272 C CB  . PHE D 1 440 ? -2.560  54.740  14.597 1.00 81.80  ? 448 PHE D CB  1 
ATOM   14273 C CG  . PHE D 1 440 ? -2.179  56.052  13.923 1.00 71.16  ? 448 PHE D CG  1 
ATOM   14274 C CD1 . PHE D 1 440 ? -1.927  57.205  14.667 1.00 88.87  ? 448 PHE D CD1 1 
ATOM   14275 C CD2 . PHE D 1 440 ? -2.008  56.107  12.556 1.00 69.04  ? 448 PHE D CD2 1 
ATOM   14276 C CE1 . PHE D 1 440 ? -1.541  58.383  14.046 1.00 92.86  ? 448 PHE D CE1 1 
ATOM   14277 C CE2 . PHE D 1 440 ? -1.624  57.271  11.934 1.00 84.77  ? 448 PHE D CE2 1 
ATOM   14278 C CZ  . PHE D 1 440 ? -1.414  58.419  12.671 1.00 93.43  ? 448 PHE D CZ  1 
ATOM   14279 N N   . LYS D 1 441 ? -0.769  54.848  17.249 1.00 72.31  ? 449 LYS D N   1 
ATOM   14280 C CA  . LYS D 1 441 ? 0.037   55.562  18.228 1.00 83.64  ? 449 LYS D CA  1 
ATOM   14281 C C   . LYS D 1 441 ? 1.378   54.873  18.458 1.00 91.27  ? 449 LYS D C   1 
ATOM   14282 O O   . LYS D 1 441 ? 2.412   55.531  18.674 1.00 85.37  ? 449 LYS D O   1 
ATOM   14283 C CB  . LYS D 1 441 ? -0.767  55.730  19.526 1.00 92.28  ? 449 LYS D CB  1 
ATOM   14284 C CG  . LYS D 1 441 ? -1.868  56.793  19.396 1.00 108.45 ? 449 LYS D CG  1 
ATOM   14285 C CD  . LYS D 1 441 ? -2.274  57.580  20.656 1.00 107.81 ? 449 LYS D CD  1 
ATOM   14286 C CE  . LYS D 1 441 ? -3.599  57.099  21.103 1.00 104.19 ? 449 LYS D CE  1 
ATOM   14287 N NZ  . LYS D 1 441 ? -4.307  58.098  21.926 1.00 91.84  ? 449 LYS D NZ  1 
ATOM   14288 N N   . GLU D 1 442 ? 1.344   53.531  18.426 1.00 93.87  ? 450 GLU D N   1 
ATOM   14289 C CA  . GLU D 1 442 ? 2.532   52.715  18.611 1.00 99.72  ? 450 GLU D CA  1 
ATOM   14290 C C   . GLU D 1 442 ? 3.481   52.934  17.437 1.00 109.92 ? 450 GLU D C   1 
ATOM   14291 O O   . GLU D 1 442 ? 4.673   53.148  17.661 1.00 144.37 ? 450 GLU D O   1 
ATOM   14292 C CB  . GLU D 1 442 ? 2.172   51.246  18.832 1.00 83.75  ? 450 GLU D CB  1 
ATOM   14293 C CG  . GLU D 1 442 ? 1.549   51.017  20.202 1.00 117.68 ? 450 GLU D CG  1 
ATOM   14294 C CD  . GLU D 1 442 ? 0.779   49.724  20.349 1.00 133.70 ? 450 GLU D CD  1 
ATOM   14295 O OE1 . GLU D 1 442 ? 0.829   48.889  19.414 1.00 131.45 ? 450 GLU D OE1 1 
ATOM   14296 O OE2 . GLU D 1 442 ? 0.102   49.595  21.397 1.00 120.46 ? 450 GLU D OE2 1 
ATOM   14297 N N   . ARG D 1 443 ? 2.949   52.909  16.210 1.00 67.57  ? 451 ARG D N   1 
ATOM   14298 C CA  . ARG D 1 443 ? 3.790   53.101  15.036 1.00 91.01  ? 451 ARG D CA  1 
ATOM   14299 C C   . ARG D 1 443 ? 4.369   54.518  15.031 1.00 117.50 ? 451 ARG D C   1 
ATOM   14300 O O   . ARG D 1 443 ? 5.526   54.713  14.637 1.00 125.81 ? 451 ARG D O   1 
ATOM   14301 C CB  . ARG D 1 443 ? 3.141   52.848  13.673 1.00 85.37  ? 451 ARG D CB  1 
ATOM   14302 C CG  . ARG D 1 443 ? 4.359   52.764  12.756 1.00 92.96  ? 451 ARG D CG  1 
ATOM   14303 C CD  . ARG D 1 443 ? 5.245   51.534  13.050 1.00 90.87  ? 451 ARG D CD  1 
ATOM   14304 N NE  . ARG D 1 443 ? 4.625   50.359  12.434 1.00 98.70  ? 451 ARG D NE  1 
ATOM   14305 C CZ  . ARG D 1 443 ? 4.288   50.251  11.135 1.00 132.81 ? 451 ARG D CZ  1 
ATOM   14306 N NH1 . ARG D 1 443 ? 4.726   51.112  10.233 1.00 139.87 ? 451 ARG D NH1 1 
ATOM   14307 N NH2 . ARG D 1 443 ? 3.500   49.276  10.722 1.00 157.91 ? 451 ARG D NH2 1 
ATOM   14308 N N   . LEU D 1 444 ? 3.541   55.499  15.437 1.00 118.02 ? 452 LEU D N   1 
ATOM   14309 C CA  . LEU D 1 444 ? 3.927   56.901  15.544 1.00 117.32 ? 452 LEU D CA  1 
ATOM   14310 C C   . LEU D 1 444 ? 5.129   57.039  16.478 1.00 116.14 ? 452 LEU D C   1 
ATOM   14311 O O   . LEU D 1 444 ? 6.053   57.792  16.181 1.00 136.98 ? 452 LEU D O   1 
ATOM   14312 C CB  . LEU D 1 444 ? 2.758   57.790  15.977 1.00 108.91 ? 452 LEU D CB  1 
ATOM   14313 C CG  . LEU D 1 444 ? 3.086   59.266  16.246 1.00 104.33 ? 452 LEU D CG  1 
ATOM   14314 C CD1 . LEU D 1 444 ? 3.586   59.970  15.017 1.00 102.63 ? 452 LEU D CD1 1 
ATOM   14315 C CD2 . LEU D 1 444 ? 1.939   60.065  16.785 1.00 121.05 ? 452 LEU D CD2 1 
ATOM   14316 N N   . ALA D 1 445 ? 5.115   56.294  17.598 1.00 116.45 ? 453 ALA D N   1 
ATOM   14317 C CA  . ALA D 1 445 ? 6.245   56.225  18.515 1.00 135.75 ? 453 ALA D CA  1 
ATOM   14318 C C   . ALA D 1 445 ? 7.419   55.491  17.847 1.00 153.10 ? 453 ALA D C   1 
ATOM   14319 O O   . ALA D 1 445 ? 8.562   55.598  18.266 1.00 173.95 ? 453 ALA D O   1 
ATOM   14320 C CB  . ALA D 1 445 ? 5.783   55.558  19.793 1.00 106.48 ? 453 ALA D CB  1 
ATOM   14321 N N   . GLY D 1 446 ? 7.085   54.769  16.771 1.00 131.94 ? 454 GLY D N   1 
ATOM   14322 C CA  . GLY D 1 446 ? 7.991   54.051  15.902 1.00 150.68 ? 454 GLY D CA  1 
ATOM   14323 C C   . GLY D 1 446 ? 9.144   54.930  15.425 1.00 149.67 ? 454 GLY D C   1 
ATOM   14324 O O   . GLY D 1 446 ? 8.968   56.093  15.074 1.00 171.17 ? 454 GLY D O   1 
ATOM   14325 N N   . ASP D 1 447 ? 10.323  54.310  15.357 1.00 130.10 ? 455 ASP D N   1 
ATOM   14326 C CA  . ASP D 1 447 ? 11.595  54.974  15.126 1.00 107.62 ? 455 ASP D CA  1 
ATOM   14327 C C   . ASP D 1 447 ? 11.598  55.714  13.784 1.00 132.30 ? 455 ASP D C   1 
ATOM   14328 O O   . ASP D 1 447 ? 12.144  56.823  13.720 1.00 128.85 ? 455 ASP D O   1 
ATOM   14329 C CB  . ASP D 1 447 ? 12.720  54.012  15.478 1.00 92.41  ? 455 ASP D CB  1 
ATOM   14330 C CG  . ASP D 1 447 ? 12.461  53.239  16.772 1.00 116.80 ? 455 ASP D CG  1 
ATOM   14331 O OD1 . ASP D 1 447 ? 11.399  52.544  16.865 1.00 93.95  ? 455 ASP D OD1 1 
ATOM   14332 O OD2 . ASP D 1 447 ? 13.297  53.351  17.708 1.00 115.22 ? 455 ASP D OD2 1 
ATOM   14333 N N   . LYS D 1 448 ? 11.042  55.104  12.720 1.00 122.19 ? 456 LYS D N   1 
ATOM   14334 C CA  . LYS D 1 448 ? 11.055  55.691  11.388 1.00 104.17 ? 456 LYS D CA  1 
ATOM   14335 C C   . LYS D 1 448 ? 10.288  57.007  11.390 1.00 97.64  ? 456 LYS D C   1 
ATOM   14336 O O   . LYS D 1 448 ? 10.728  58.015  10.856 1.00 117.82 ? 456 LYS D O   1 
ATOM   14337 C CB  . LYS D 1 448 ? 10.449  54.676  10.416 1.00 107.13 ? 456 LYS D CB  1 
ATOM   14338 C CG  . LYS D 1 448 ? 10.623  54.908  8.911  1.00 127.15 ? 456 LYS D CG  1 
ATOM   14339 C CD  . LYS D 1 448 ? 10.417  53.602  8.139  1.00 145.67 ? 456 LYS D CD  1 
ATOM   14340 C CE  . LYS D 1 448 ? 11.091  53.461  6.808  1.00 127.38 ? 456 LYS D CE  1 
ATOM   14341 N NZ  . LYS D 1 448 ? 10.436  54.293  5.796  1.00 140.74 ? 456 LYS D NZ  1 
ATOM   14342 N N   . TYR D 1 449 ? 9.105   56.989  11.988 1.00 118.24 ? 457 TYR D N   1 
ATOM   14343 C CA  . TYR D 1 449 ? 8.238   58.147  12.055 1.00 111.29 ? 457 TYR D CA  1 
ATOM   14344 C C   . TYR D 1 449 ? 8.784   59.240  12.970 1.00 115.38 ? 457 TYR D C   1 
ATOM   14345 O O   . TYR D 1 449 ? 8.725   60.396  12.592 1.00 142.46 ? 457 TYR D O   1 
ATOM   14346 C CB  . TYR D 1 449 ? 6.842   57.589  12.331 1.00 113.41 ? 457 TYR D CB  1 
ATOM   14347 C CG  . TYR D 1 449 ? 6.323   57.040  11.010 1.00 112.39 ? 457 TYR D CG  1 
ATOM   14348 C CD1 . TYR D 1 449 ? 6.300   57.844  9.869  1.00 106.05 ? 457 TYR D CD1 1 
ATOM   14349 C CD2 . TYR D 1 449 ? 5.940   55.713  10.884 1.00 119.22 ? 457 TYR D CD2 1 
ATOM   14350 C CE1 . TYR D 1 449 ? 5.812   57.377  8.660  1.00 96.41  ? 457 TYR D CE1 1 
ATOM   14351 C CE2 . TYR D 1 449 ? 5.492   55.217  9.668  1.00 127.62 ? 457 TYR D CE2 1 
ATOM   14352 C CZ  . TYR D 1 449 ? 5.424   56.054  8.563  1.00 105.37 ? 457 TYR D CZ  1 
ATOM   14353 O OH  . TYR D 1 449 ? 4.983   55.607  7.362  1.00 91.34  ? 457 TYR D OH  1 
ATOM   14354 N N   . GLN D 1 450 ? 9.318   58.853  14.128 1.00 104.17 ? 458 GLN D N   1 
ATOM   14355 C CA  . GLN D 1 450 ? 9.887   59.790  15.096 1.00 112.08 ? 458 GLN D CA  1 
ATOM   14356 C C   . GLN D 1 450 ? 10.901  60.715  14.399 1.00 132.81 ? 458 GLN D C   1 
ATOM   14357 O O   . GLN D 1 450 ? 11.033  61.900  14.732 1.00 151.53 ? 458 GLN D O   1 
ATOM   14358 C CB  . GLN D 1 450 ? 10.523  59.036  16.268 1.00 111.10 ? 458 GLN D CB  1 
ATOM   14359 C CG  . GLN D 1 450 ? 9.543   58.441  17.284 1.00 95.17  ? 458 GLN D CG  1 
ATOM   14360 C CD  . GLN D 1 450 ? 8.685   59.475  17.965 1.00 89.72  ? 458 GLN D CD  1 
ATOM   14361 O OE1 . GLN D 1 450 ? 7.493   59.642  17.686 1.00 94.69  ? 458 GLN D OE1 1 
ATOM   14362 N NE2 . GLN D 1 450 ? 9.311   60.207  18.863 1.00 106.02 ? 458 GLN D NE2 1 
ATOM   14363 N N   . ALA D 1 451 ? 11.630  60.162  13.419 1.00 111.94 ? 459 ALA D N   1 
ATOM   14364 C CA  . ALA D 1 451 ? 12.604  60.931  12.654 1.00 113.02 ? 459 ALA D CA  1 
ATOM   14365 C C   . ALA D 1 451 ? 11.928  62.041  11.834 1.00 102.46 ? 459 ALA D C   1 
ATOM   14366 O O   . ALA D 1 451 ? 12.325  63.204  11.923 1.00 103.39 ? 459 ALA D O   1 
ATOM   14367 C CB  . ALA D 1 451 ? 13.434  59.986  11.809 1.00 104.49 ? 459 ALA D CB  1 
ATOM   14368 N N   . ALA D 1 452 ? 10.879  61.683  11.075 1.00 116.03 ? 460 ALA D N   1 
ATOM   14369 C CA  . ALA D 1 452 ? 10.097  62.605  10.245 1.00 113.92 ? 460 ALA D CA  1 
ATOM   14370 C C   . ALA D 1 452 ? 9.460   63.687  11.110 1.00 126.07 ? 460 ALA D C   1 
ATOM   14371 O O   . ALA D 1 452 ? 9.504   64.875  10.771 1.00 112.72 ? 460 ALA D O   1 
ATOM   14372 C CB  . ALA D 1 452 ? 9.000   61.864  9.480  1.00 68.82  ? 460 ALA D CB  1 
ATOM   14373 N N   . VAL D 1 453 ? 8.867   63.232  12.225 1.00 115.98 ? 461 VAL D N   1 
ATOM   14374 C CA  . VAL D 1 453 ? 8.206   64.078  13.196 1.00 98.67  ? 461 VAL D CA  1 
ATOM   14375 C C   . VAL D 1 453 ? 9.192   65.093  13.745 1.00 110.14 ? 461 VAL D C   1 
ATOM   14376 O O   . VAL D 1 453 ? 8.819   66.259  13.812 1.00 105.07 ? 461 VAL D O   1 
ATOM   14377 C CB  . VAL D 1 453 ? 7.594   63.191  14.302 1.00 113.62 ? 461 VAL D CB  1 
ATOM   14378 C CG1 . VAL D 1 453 ? 7.625   63.787  15.735 1.00 99.94  ? 461 VAL D CG1 1 
ATOM   14379 C CG2 . VAL D 1 453 ? 6.225   62.701  13.829 1.00 98.09  ? 461 VAL D CG2 1 
ATOM   14380 N N   . GLN D 1 454 ? 10.409  64.643  14.114 1.00 117.62 ? 462 GLN D N   1 
ATOM   14381 C CA  . GLN D 1 454 ? 11.391  65.550  14.686 1.00 119.44 ? 462 GLN D CA  1 
ATOM   14382 C C   . GLN D 1 454 ? 11.774  66.633  13.668 1.00 108.25 ? 462 GLN D C   1 
ATOM   14383 O O   . GLN D 1 454 ? 11.905  67.817  14.009 1.00 101.16 ? 462 GLN D O   1 
ATOM   14384 C CB  . GLN D 1 454 ? 12.606  64.945  15.398 1.00 94.74  ? 462 GLN D CB  1 
ATOM   14385 C CG  . GLN D 1 454 ? 13.695  66.005  15.520 1.00 89.76  ? 462 GLN D CG  1 
ATOM   14386 C CD  . GLN D 1 454 ? 14.133  66.303  16.948 1.00 141.60 ? 462 GLN D CD  1 
ATOM   14387 O OE1 . GLN D 1 454 ? 14.738  65.456  17.610 1.00 166.38 ? 462 GLN D OE1 1 
ATOM   14388 N NE2 . GLN D 1 454 ? 13.843  67.501  17.454 1.00 128.23 ? 462 GLN D NE2 1 
ATOM   14389 N N   . ALA D 1 455 ? 11.889  66.230  12.393 1.00 101.08 ? 463 ALA D N   1 
ATOM   14390 C CA  . ALA D 1 455 ? 12.142  67.145  11.292 1.00 105.52 ? 463 ALA D CA  1 
ATOM   14391 C C   . ALA D 1 455 ? 11.137  68.285  11.325 1.00 118.56 ? 463 ALA D C   1 
ATOM   14392 O O   . ALA D 1 455 ? 11.457  69.475  11.491 1.00 115.74 ? 463 ALA D O   1 
ATOM   14393 C CB  . ALA D 1 455 ? 11.890  66.396  9.999  1.00 77.77  ? 463 ALA D CB  1 
ATOM   14394 N N   . LEU D 1 456 ? 9.894   67.867  11.073 1.00 120.33 ? 464 LEU D N   1 
ATOM   14395 C CA  . LEU D 1 456 ? 8.813   68.814  10.931 1.00 108.70 ? 464 LEU D CA  1 
ATOM   14396 C C   . LEU D 1 456 ? 8.705   69.653  12.203 1.00 102.76 ? 464 LEU D C   1 
ATOM   14397 O O   . LEU D 1 456 ? 8.637   70.876  12.107 1.00 63.79  ? 464 LEU D O   1 
ATOM   14398 C CB  . LEU D 1 456 ? 7.539   68.051  10.591 1.00 85.16  ? 464 LEU D CB  1 
ATOM   14399 C CG  . LEU D 1 456 ? 6.290   68.901  10.387 1.00 84.63  ? 464 LEU D CG  1 
ATOM   14400 C CD1 . LEU D 1 456 ? 6.629   69.935  9.377  1.00 86.01  ? 464 LEU D CD1 1 
ATOM   14401 C CD2 . LEU D 1 456 ? 5.159   68.014  9.869  1.00 100.50 ? 464 LEU D CD2 1 
ATOM   14402 N N   . ARG D 1 457 ? 8.752   68.982  13.369 1.00 91.45  ? 465 ARG D N   1 
ATOM   14403 C CA  . ARG D 1 457 ? 8.614   69.628  14.659 1.00 98.91  ? 465 ARG D CA  1 
ATOM   14404 C C   . ARG D 1 457 ? 9.584   70.796  14.746 1.00 95.75  ? 465 ARG D C   1 
ATOM   14405 O O   . ARG D 1 457 ? 9.173   71.896  15.118 1.00 101.65 ? 465 ARG D O   1 
ATOM   14406 C CB  . ARG D 1 457 ? 8.798   68.610  15.789 1.00 116.34 ? 465 ARG D CB  1 
ATOM   14407 C CG  . ARG D 1 457 ? 8.423   68.995  17.211 1.00 102.19 ? 465 ARG D CG  1 
ATOM   14408 C CD  . ARG D 1 457 ? 8.443   67.869  18.282 1.00 101.53 ? 465 ARG D CD  1 
ATOM   14409 N NE  . ARG D 1 457 ? 9.679   67.405  18.926 1.00 103.39 ? 465 ARG D NE  1 
ATOM   14410 C CZ  . ARG D 1 457 ? 10.581  68.177  19.513 1.00 151.66 ? 465 ARG D CZ  1 
ATOM   14411 N NH1 . ARG D 1 457 ? 10.394  69.490  19.640 1.00 196.76 ? 465 ARG D NH1 1 
ATOM   14412 N NH2 . ARG D 1 457 ? 11.697  67.630  19.945 1.00 171.37 ? 465 ARG D NH2 1 
ATOM   14413 N N   . GLU D 1 458 ? 10.840  70.556  14.344 1.00 95.43  ? 466 GLU D N   1 
ATOM   14414 C CA  . GLU D 1 458 ? 11.880  71.566  14.504 1.00 124.09 ? 466 GLU D CA  1 
ATOM   14415 C C   . GLU D 1 458 ? 11.544  72.805  13.671 1.00 110.06 ? 466 GLU D C   1 
ATOM   14416 O O   . GLU D 1 458 ? 11.555  73.939  14.183 1.00 102.17 ? 466 GLU D O   1 
ATOM   14417 C CB  . GLU D 1 458 ? 13.262  71.039  14.140 1.00 121.46 ? 466 GLU D CB  1 
ATOM   14418 C CG  . GLU D 1 458 ? 13.867  70.045  15.117 1.00 123.28 ? 466 GLU D CG  1 
ATOM   14419 C CD  . GLU D 1 458 ? 14.538  69.333  13.963 1.00 125.11 ? 466 GLU D CD  1 
ATOM   14420 O OE1 . GLU D 1 458 ? 15.096  70.069  13.102 1.00 71.99  ? 466 GLU D OE1 1 
ATOM   14421 O OE2 . GLU D 1 458 ? 14.446  68.085  13.879 1.00 161.96 ? 466 GLU D OE2 1 
ATOM   14422 N N   . GLU D 1 459 ? 11.175  72.570  12.399 1.00 101.81 ? 467 GLU D N   1 
ATOM   14423 C CA  . GLU D 1 459 ? 10.815  73.654  11.488 1.00 98.71  ? 467 GLU D CA  1 
ATOM   14424 C C   . GLU D 1 459 ? 9.667   74.469  12.083 1.00 116.01 ? 467 GLU D C   1 
ATOM   14425 O O   . GLU D 1 459 ? 9.657   75.696  12.040 1.00 124.85 ? 467 GLU D O   1 
ATOM   14426 C CB  . GLU D 1 459 ? 10.425  73.132  10.104 1.00 83.06  ? 467 GLU D CB  1 
ATOM   14427 C CG  . GLU D 1 459 ? 11.257  73.824  9.029  1.00 97.79  ? 467 GLU D CG  1 
ATOM   14428 C CD  . GLU D 1 459 ? 10.828  73.593  7.593  1.00 124.58 ? 467 GLU D CD  1 
ATOM   14429 O OE1 . GLU D 1 459 ? 10.819  72.396  7.160  1.00 98.37  ? 467 GLU D OE1 1 
ATOM   14430 O OE2 . GLU D 1 459 ? 10.494  74.623  6.938  1.00 110.43 ? 467 GLU D OE2 1 
ATOM   14431 N N   . VAL D 1 460 ? 8.677   73.739  12.593 1.00 130.51 ? 468 VAL D N   1 
ATOM   14432 C CA  . VAL D 1 460 ? 7.481   74.307  13.188 1.00 102.73 ? 468 VAL D CA  1 
ATOM   14433 C C   . VAL D 1 460 ? 7.854   75.170  14.387 1.00 84.89  ? 468 VAL D C   1 
ATOM   14434 O O   . VAL D 1 460 ? 7.400   76.307  14.496 1.00 74.22  ? 468 VAL D O   1 
ATOM   14435 C CB  . VAL D 1 460 ? 6.497   73.178  13.531 1.00 85.36  ? 468 VAL D CB  1 
ATOM   14436 C CG1 . VAL D 1 460 ? 5.435   73.644  14.492 1.00 72.12  ? 468 VAL D CG1 1 
ATOM   14437 C CG2 . VAL D 1 460 ? 5.867   72.648  12.241 1.00 122.32 ? 468 VAL D CG2 1 
ATOM   14438 N N   . GLU D 1 461 ? 8.665   74.629  15.292 1.00 82.84  ? 469 GLU D N   1 
ATOM   14439 C CA  . GLU D 1 461 ? 9.046   75.368  16.496 1.00 102.93 ? 469 GLU D CA  1 
ATOM   14440 C C   . GLU D 1 461 ? 9.795   76.654  16.117 1.00 100.70 ? 469 GLU D C   1 
ATOM   14441 O O   . GLU D 1 461 ? 9.534   77.716  16.670 1.00 130.51 ? 469 GLU D O   1 
ATOM   14442 C CB  . GLU D 1 461 ? 9.754   74.498  17.543 1.00 95.71  ? 469 GLU D CB  1 
ATOM   14443 C CG  . GLU D 1 461 ? 8.863   73.382  18.078 1.00 88.56  ? 469 GLU D CG  1 
ATOM   14444 C CD  . GLU D 1 461 ? 9.472   72.432  19.088 1.00 117.23 ? 469 GLU D CD  1 
ATOM   14445 O OE1 . GLU D 1 461 ? 10.444  72.770  19.764 1.00 141.31 ? 469 GLU D OE1 1 
ATOM   14446 O OE2 . GLU D 1 461 ? 9.032   71.260  19.099 1.00 107.15 ? 469 GLU D OE2 1 
ATOM   14447 N N   . SER D 1 462 ? 10.750  76.549  15.185 1.00 88.49  ? 470 SER D N   1 
ATOM   14448 C CA  . SER D 1 462 ? 11.490  77.721  14.744 1.00 104.09 ? 470 SER D CA  1 
ATOM   14449 C C   . SER D 1 462 ? 10.557  78.782  14.156 1.00 103.27 ? 470 SER D C   1 
ATOM   14450 O O   . SER D 1 462 ? 10.735  79.948  14.468 1.00 119.17 ? 470 SER D O   1 
ATOM   14451 C CB  . SER D 1 462 ? 12.611  77.374  13.811 1.00 95.63  ? 470 SER D CB  1 
ATOM   14452 O OG  . SER D 1 462 ? 12.157  76.303  12.998 1.00 132.49 ? 470 SER D OG  1 
ATOM   14453 N N   . PHE D 1 463 ? 9.563   78.400  13.348 1.00 82.06  ? 471 PHE D N   1 
ATOM   14454 C CA  . PHE D 1 463 ? 8.596   79.349  12.792 1.00 90.79  ? 471 PHE D CA  1 
ATOM   14455 C C   . PHE D 1 463 ? 7.796   80.075  13.885 1.00 106.08 ? 471 PHE D C   1 
ATOM   14456 O O   . PHE D 1 463 ? 7.673   81.315  13.914 1.00 103.73 ? 471 PHE D O   1 
ATOM   14457 C CB  . PHE D 1 463 ? 7.608   78.656  11.852 1.00 70.21  ? 471 PHE D CB  1 
ATOM   14458 C CG  . PHE D 1 463 ? 6.591   79.614  11.237 1.00 94.81  ? 471 PHE D CG  1 
ATOM   14459 C CD1 . PHE D 1 463 ? 6.959   80.828  10.644 1.00 81.43  ? 471 PHE D CD1 1 
ATOM   14460 C CD2 . PHE D 1 463 ? 5.242   79.275  11.226 1.00 120.07 ? 471 PHE D CD2 1 
ATOM   14461 C CE1 . PHE D 1 463 ? 6.001   81.659  10.068 1.00 101.30 ? 471 PHE D CE1 1 
ATOM   14462 C CE2 . PHE D 1 463 ? 4.291   80.095  10.619 1.00 132.78 ? 471 PHE D CE2 1 
ATOM   14463 C CZ  . PHE D 1 463 ? 4.661   81.297  10.041 1.00 122.02 ? 471 PHE D CZ  1 
ATOM   14464 N N   . ALA D 1 464 ? 7.290   79.282  14.824 1.00 95.73  ? 472 ALA D N   1 
ATOM   14465 C CA  . ALA D 1 464 ? 6.540   79.807  15.953 1.00 99.03  ? 472 ALA D CA  1 
ATOM   14466 C C   . ALA D 1 464 ? 7.396   80.729  16.830 1.00 104.43 ? 472 ALA D C   1 
ATOM   14467 O O   . ALA D 1 464 ? 6.873   81.684  17.388 1.00 106.56 ? 472 ALA D O   1 
ATOM   14468 C CB  . ALA D 1 464 ? 6.002   78.649  16.754 1.00 101.39 ? 472 ALA D CB  1 
ATOM   14469 N N   . SER D 1 465 ? 8.666   80.359  17.038 1.00 93.31  ? 473 SER D N   1 
ATOM   14470 C CA  . SER D 1 465 ? 9.675   81.091  17.787 1.00 89.53  ? 473 SER D CA  1 
ATOM   14471 C C   . SER D 1 465 ? 9.797   82.519  17.287 1.00 111.57 ? 473 SER D C   1 
ATOM   14472 O O   . SER D 1 465 ? 10.353  83.352  17.975 1.00 130.68 ? 473 SER D O   1 
ATOM   14473 C CB  . SER D 1 465 ? 11.035  80.448  17.663 1.00 89.39  ? 473 SER D CB  1 
ATOM   14474 O OG  . SER D 1 465 ? 11.020  79.093  18.083 1.00 129.34 ? 473 SER D OG  1 
ATOM   14475 N N   . LEU D 1 466 ? 9.379   82.773  16.055 1.00 123.35 ? 474 LEU D N   1 
ATOM   14476 C CA  . LEU D 1 466 ? 9.633   84.069  15.444 1.00 127.90 ? 474 LEU D CA  1 
ATOM   14477 C C   . LEU D 1 466 ? 8.608   85.103  15.881 1.00 126.16 ? 474 LEU D C   1 
ATOM   14478 O O   . LEU D 1 466 ? 8.853   86.286  15.730 1.00 187.59 ? 474 LEU D O   1 
ATOM   14479 C CB  . LEU D 1 466 ? 9.706   83.925  13.930 1.00 115.07 ? 474 LEU D CB  1 
ATOM   14480 C CG  . LEU D 1 466 ? 10.846  82.984  13.531 1.00 101.63 ? 474 LEU D CG  1 
ATOM   14481 C CD1 . LEU D 1 466 ? 11.511  83.163  12.164 1.00 85.17  ? 474 LEU D CD1 1 
ATOM   14482 C CD2 . LEU D 1 466 ? 11.850  82.998  14.720 1.00 61.51  ? 474 LEU D CD2 1 
ATOM   14483 N N   . PHE D 1 467 ? 7.459   84.661  16.378 1.00 99.98  ? 475 PHE D N   1 
ATOM   14484 C CA  . PHE D 1 467 ? 6.450   85.586  16.866 1.00 98.32  ? 475 PHE D CA  1 
ATOM   14485 C C   . PHE D 1 467 ? 6.414   85.614  18.397 1.00 109.09 ? 475 PHE D C   1 
ATOM   14486 O O   . PHE D 1 467 ? 6.779   84.644  19.067 1.00 128.87 ? 475 PHE D O   1 
ATOM   14487 C CB  . PHE D 1 467 ? 5.066   85.141  16.407 1.00 112.69 ? 475 PHE D CB  1 
ATOM   14488 C CG  . PHE D 1 467 ? 4.935   84.926  14.906 1.00 122.42 ? 475 PHE D CG  1 
ATOM   14489 C CD1 . PHE D 1 467 ? 5.356   83.727  14.304 1.00 134.48 ? 475 PHE D CD1 1 
ATOM   14490 C CD2 . PHE D 1 467 ? 4.339   85.910  14.113 1.00 110.27 ? 475 PHE D CD2 1 
ATOM   14491 C CE1 . PHE D 1 467 ? 5.217   83.533  12.939 1.00 143.92 ? 475 PHE D CE1 1 
ATOM   14492 C CE2 . PHE D 1 467 ? 4.224   85.721  12.744 1.00 125.16 ? 475 PHE D CE2 1 
ATOM   14493 C CZ  . PHE D 1 467 ? 4.650   84.527  12.163 1.00 139.66 ? 475 PHE D CZ  1 
ATOM   14494 N N   . PRO D 1 468 ? 5.938   86.728  19.012 1.00 98.23  ? 476 PRO D N   1 
ATOM   14495 C CA  . PRO D 1 468 ? 6.027   86.900  20.466 1.00 95.02  ? 476 PRO D CA  1 
ATOM   14496 C C   . PRO D 1 468 ? 4.904   86.092  21.109 1.00 125.29 ? 476 PRO D C   1 
ATOM   14497 O O   . PRO D 1 468 ? 3.974   85.615  20.425 1.00 119.13 ? 476 PRO D O   1 
ATOM   14498 C CB  . PRO D 1 468 ? 5.849   88.429  20.614 1.00 86.35  ? 476 PRO D CB  1 
ATOM   14499 C CG  . PRO D 1 468 ? 4.894   88.823  19.463 1.00 80.81  ? 476 PRO D CG  1 
ATOM   14500 C CD  . PRO D 1 468 ? 5.253   87.854  18.342 1.00 91.72  ? 476 PRO D CD  1 
ATOM   14501 N N   . LEU D 1 469 ? 4.989   85.983  22.442 1.00 110.33 ? 477 LEU D N   1 
ATOM   14502 C CA  . LEU D 1 469 ? 3.967   85.294  23.219 1.00 103.58 ? 477 LEU D CA  1 
ATOM   14503 C C   . LEU D 1 469 ? 3.394   86.204  24.296 1.00 113.03 ? 477 LEU D C   1 
ATOM   14504 O O   . LEU D 1 469 ? 4.023   86.408  25.340 1.00 161.35 ? 477 LEU D O   1 
ATOM   14505 C CB  . LEU D 1 469 ? 4.638   84.106  23.885 1.00 100.56 ? 477 LEU D CB  1 
ATOM   14506 C CG  . LEU D 1 469 ? 3.698   83.102  24.542 1.00 76.47  ? 477 LEU D CG  1 
ATOM   14507 C CD1 . LEU D 1 469 ? 3.180   82.300  23.347 1.00 78.66  ? 477 LEU D CD1 1 
ATOM   14508 C CD2 . LEU D 1 469 ? 4.518   82.235  25.538 1.00 54.21  ? 477 LEU D CD2 1 
ATOM   14509 N N   . PRO D 1 470 ? 2.176   86.756  24.089 1.00 107.07 ? 478 PRO D N   1 
ATOM   14510 C CA  . PRO D 1 470 ? 1.665   87.851  24.922 1.00 93.31  ? 478 PRO D CA  1 
ATOM   14511 C C   . PRO D 1 470 ? 1.690   87.454  26.397 1.00 125.81 ? 478 PRO D C   1 
ATOM   14512 O O   . PRO D 1 470 ? 1.462   86.278  26.733 1.00 117.56 ? 478 PRO D O   1 
ATOM   14513 C CB  . PRO D 1 470 ? 0.216   88.041  24.425 1.00 101.62 ? 478 PRO D CB  1 
ATOM   14514 C CG  . PRO D 1 470 ? 0.168   87.438  23.046 1.00 114.94 ? 478 PRO D CG  1 
ATOM   14515 C CD  . PRO D 1 470 ? 1.248   86.370  23.011 1.00 126.53 ? 478 PRO D CD  1 
ATOM   14516 N N   . GLY D 1 471 ? 1.971   88.432  27.270 1.00 124.57 ? 479 GLY D N   1 
ATOM   14517 C CA  . GLY D 1 471 ? 1.737   88.224  28.692 1.00 119.02 ? 479 GLY D CA  1 
ATOM   14518 C C   . GLY D 1 471 ? 2.936   87.554  29.346 1.00 117.68 ? 479 GLY D C   1 
ATOM   14519 O O   . GLY D 1 471 ? 3.386   86.496  28.927 1.00 146.65 ? 479 GLY D O   1 
ATOM   14520 N N   . LEU D 1 472 ? 3.451   88.195  30.386 1.00 134.26 ? 480 LEU D N   1 
ATOM   14521 C CA  . LEU D 1 472 ? 4.739   87.856  30.970 1.00 143.79 ? 480 LEU D CA  1 
ATOM   14522 C C   . LEU D 1 472 ? 4.615   88.223  32.466 1.00 140.57 ? 480 LEU D C   1 
ATOM   14523 O O   . LEU D 1 472 ? 5.398   89.129  32.933 1.00 143.51 ? 480 LEU D O   1 
ATOM   14524 C CB  . LEU D 1 472 ? 5.953   88.522  30.288 1.00 128.75 ? 480 LEU D CB  1 
ATOM   14525 C CG  . LEU D 1 472 ? 6.407   88.127  28.856 1.00 106.91 ? 480 LEU D CG  1 
ATOM   14526 C CD1 . LEU D 1 472 ? 6.900   86.667  28.593 1.00 49.69  ? 480 LEU D CD1 1 
ATOM   14527 C CD2 . LEU D 1 472 ? 5.695   88.835  27.593 1.00 79.78  ? 480 LEU D CD2 1 
ATOM   14528 O OXT . LEU D 1 472 ? 3.663   87.640  33.112 1.00 73.16  ? 480 LEU D OXT 1 
HETATM 14529 N N1  . PLP E 2 .   ? -19.008 75.389  52.515 1.00 78.99  ? 500 PLP A N1  1 
HETATM 14530 C C2  . PLP E 2 .   ? -18.796 76.058  53.629 1.00 84.29  ? 500 PLP A C2  1 
HETATM 14531 C C2A . PLP E 2 .   ? -19.289 75.426  54.882 1.00 86.56  ? 500 PLP A C2A 1 
HETATM 14532 C C3  . PLP E 2 .   ? -18.124 77.303  53.608 1.00 96.98  ? 500 PLP A C3  1 
HETATM 14533 O O3  . PLP E 2 .   ? -17.855 78.076  54.713 1.00 120.40 ? 500 PLP A O3  1 
HETATM 14534 C C4  . PLP E 2 .   ? -17.677 77.848  52.389 1.00 109.05 ? 500 PLP A C4  1 
HETATM 14535 C C4A . PLP E 2 .   ? -16.943 79.120  52.406 1.00 118.03 ? 500 PLP A C4A 1 
HETATM 14536 C C5  . PLP E 2 .   ? -17.946 77.123  51.212 1.00 109.62 ? 500 PLP A C5  1 
HETATM 14537 C C6  . PLP E 2 .   ? -18.570 75.908  51.345 1.00 118.55 ? 500 PLP A C6  1 
HETATM 14538 C C5A . PLP E 2 .   ? -17.477 77.541  49.842 1.00 78.71  ? 500 PLP A C5A 1 
HETATM 14539 O O4P . PLP E 2 .   ? -17.826 78.870  49.360 1.00 69.17  ? 500 PLP A O4P 1 
HETATM 14540 P P   . PLP E 2 .   ? -16.964 79.332  48.036 1.00 83.12  ? 500 PLP A P   1 
HETATM 14541 O O1P . PLP E 2 .   ? -17.533 78.550  46.811 1.00 80.16  ? 500 PLP A O1P 1 
HETATM 14542 O O2P . PLP E 2 .   ? -15.502 78.963  48.343 1.00 82.63  ? 500 PLP A O2P 1 
HETATM 14543 O O3P . PLP E 2 .   ? -17.113 80.855  47.855 1.00 81.55  ? 500 PLP A O3P 1 
HETATM 14544 N N1  . PLP F 2 .   ? -56.000 53.673  25.851 1.00 86.09  ? 500 PLP B N1  1 
HETATM 14545 C C2  . PLP F 2 .   ? -56.714 54.016  24.785 1.00 79.66  ? 500 PLP B C2  1 
HETATM 14546 C C2A . PLP F 2 .   ? -56.169 53.627  23.452 1.00 96.98  ? 500 PLP B C2A 1 
HETATM 14547 C C3  . PLP F 2 .   ? -57.955 54.701  24.924 1.00 80.09  ? 500 PLP B C3  1 
HETATM 14548 O O3  . PLP F 2 .   ? -58.743 55.044  23.829 1.00 86.81  ? 500 PLP B O3  1 
HETATM 14549 C C4  . PLP F 2 .   ? -58.424 55.044  26.218 1.00 84.11  ? 500 PLP B C4  1 
HETATM 14550 C C4A . PLP F 2 .   ? -59.692 55.756  26.444 1.00 83.06  ? 500 PLP B C4A 1 
HETATM 14551 C C5  . PLP F 2 .   ? -57.647 54.669  27.320 1.00 96.32  ? 500 PLP B C5  1 
HETATM 14552 C C6  . PLP F 2 .   ? -56.471 53.993  27.084 1.00 123.05 ? 500 PLP B C6  1 
HETATM 14553 C C5A . PLP F 2 .   ? -58.094 54.965  28.724 1.00 78.99  ? 500 PLP B C5A 1 
HETATM 14554 O O4P . PLP F 2 .   ? -59.542 54.825  28.886 1.00 77.50  ? 500 PLP B O4P 1 
HETATM 14555 P P   . PLP F 2 .   ? -60.233 54.193  30.237 1.00 98.16  ? 500 PLP B P   1 
HETATM 14556 O O1P . PLP F 2 .   ? -60.700 52.824  29.745 1.00 100.71 ? 500 PLP B O1P 1 
HETATM 14557 O O2P . PLP F 2 .   ? -61.426 55.080  30.597 1.00 103.24 ? 500 PLP B O2P 1 
HETATM 14558 O O3P . PLP F 2 .   ? -59.193 54.173  31.391 1.00 74.00  ? 500 PLP B O3P 1 
HETATM 14559 N N1  . PLP G 2 .   ? -57.036 55.755  52.428 1.00 60.99  ? 500 PLP C N1  1 
HETATM 14560 C C2  . PLP G 2 .   ? -57.625 55.146  53.432 1.00 54.60  ? 500 PLP C C2  1 
HETATM 14561 C C2A . PLP G 2 .   ? -57.301 55.678  54.784 1.00 63.23  ? 500 PLP C C2A 1 
HETATM 14562 C C3  . PLP G 2 .   ? -58.561 54.110  53.192 1.00 56.74  ? 500 PLP C C3  1 
HETATM 14563 O O3  . PLP G 2 .   ? -59.292 53.455  54.125 1.00 64.92  ? 500 PLP C O3  1 
HETATM 14564 C C4  . PLP G 2 .   ? -58.782 53.647  51.873 1.00 80.26  ? 500 PLP C C4  1 
HETATM 14565 C C4A . PLP G 2 .   ? -59.760 52.587  51.593 1.00 65.28  ? 500 PLP C C4A 1 
HETATM 14566 C C5  . PLP G 2 .   ? -58.073 54.266  50.827 1.00 97.17  ? 500 PLP C C5  1 
HETATM 14567 C C6  . PLP G 2 .   ? -57.244 55.311  51.162 1.00 95.99  ? 500 PLP C C6  1 
HETATM 14568 C C5A . PLP G 2 .   ? -58.279 53.890  49.386 1.00 76.13  ? 500 PLP C C5A 1 
HETATM 14569 O O4P . PLP G 2 .   ? -57.916 52.531  49.004 1.00 70.34  ? 500 PLP C O4P 1 
HETATM 14570 P P   . PLP G 2 .   ? -58.706 51.919  47.703 1.00 84.10  ? 500 PLP C P   1 
HETATM 14571 O O1P . PLP G 2 .   ? -58.078 52.639  46.440 1.00 49.51  ? 500 PLP C O1P 1 
HETATM 14572 O O2P . PLP G 2 .   ? -60.174 52.249  47.972 1.00 87.95  ? 500 PLP C O2P 1 
HETATM 14573 O O3P . PLP G 2 .   ? -58.579 50.378  47.694 1.00 85.33  ? 500 PLP C O3P 1 
HETATM 14574 N N1  . PLP H 2 .   ? -20.000 76.841  25.881 1.00 75.82  ? 500 PLP D N1  1 
HETATM 14575 C C2  . PLP H 2 .   ? -19.291 77.131  24.812 1.00 66.54  ? 500 PLP D C2  1 
HETATM 14576 C C2A . PLP H 2 .   ? -20.028 77.224  23.521 1.00 68.05  ? 500 PLP D C2A 1 
HETATM 14577 C C3  . PLP H 2 .   ? -17.912 77.413  24.941 1.00 70.95  ? 500 PLP D C3  1 
HETATM 14578 O O3  . PLP H 2 .   ? -17.106 77.772  23.900 1.00 88.23  ? 500 PLP D O3  1 
HETATM 14579 C C4  . PLP H 2 .   ? -17.280 77.323  26.200 1.00 79.09  ? 500 PLP D C4  1 
HETATM 14580 C C4A . PLP H 2 .   ? -15.862 77.648  26.361 1.00 62.09  ? 500 PLP D C4A 1 
HETATM 14581 C C5  . PLP H 2 .   ? -18.048 76.978  27.323 1.00 93.28  ? 500 PLP D C5  1 
HETATM 14582 C C6  . PLP H 2 .   ? -19.389 76.761  27.096 1.00 116.85 ? 500 PLP D C6  1 
HETATM 14583 C C5A . PLP H 2 .   ? -17.472 76.884  28.713 1.00 70.38  ? 500 PLP D C5A 1 
HETATM 14584 O O4P . PLP H 2 .   ? -16.050 77.220  28.844 1.00 71.39  ? 500 PLP D O4P 1 
HETATM 14585 P P   . PLP H 2 .   ? -15.382 76.875  30.313 1.00 93.43  ? 500 PLP D P   1 
HETATM 14586 O O1P . PLP H 2 .   ? -15.301 75.344  30.344 1.00 88.50  ? 500 PLP D O1P 1 
HETATM 14587 O O2P . PLP H 2 .   ? -13.924 77.509  30.597 1.00 65.95  ? 500 PLP D O2P 1 
HETATM 14588 O O3P . PLP H 2 .   ? -16.526 77.408  31.209 1.00 65.74  ? 500 PLP D O3P 1 
# 
