data_8XK9
# 
_entry.id   8XK9 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8XK9         pdb_00008xk9 10.2210/pdb8xk9/pdb 
WWPDB D_1300043697 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8XK9 
_pdbx_database_status.recvd_initial_deposition_date   2023-12-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB . 8XJR unspecified 
PDB . 8XK7 unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              wgong@ustc.edu.cn 
_pdbx_contact_author.name_first         Weimin 
_pdbx_contact_author.name_last          Gong 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6723-1298 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Wen, C.'  1 ? 
'Liu, H.'  2 ? 
'Yang, L.' 3 ? 
'Gong, W.' 4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Mol.Biol. 
_citation.journal_id_ASTM           JMOBAK 
_citation.journal_id_CSD            0070 
_citation.journal_id_ISSN           1089-8638 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            436 
_citation.language                  ? 
_citation.page_first                168744 
_citation.page_last                 168744 
_citation.title                     
;Structural Basis for C2'-methoxy Recognition by DNA Polymerases and Function Improvement.
;
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.jmb.2024.168744 
_citation.pdbx_database_id_PubMed   39147125 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Wen, C.'  1 ? 
primary 'Wang, G.' 2 ? 
primary 'Yang, L.' 3 ? 
primary 'Chen, T.' 4 ? 
primary 'Liu, H.'  5 ? 
primary 'Gong, W.' 6 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     syn 
;DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3')
;
3617.371  2   ?       ? ? ? 
2 polymer     syn 
;DNA (5'-D(*AP*AP*CP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-R(P*(OMG))-3')
;
4970.217  2   ?       ? ? ? 
3 polymer     man 'DNA polymerase I, thermostable' 60796.840 2   2.7.7.7 ? ? ? 
4 non-polymer syn 'MAGNESIUM ION' 24.305    6   ?       ? ? ? 
5 non-polymer syn 
;[[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
;
537.207   2   ?       ? ? ? 
6 non-polymer syn 'DI(HYDROXYETHYL)ETHER' 106.120   2   ?       ? ? ? 
7 non-polymer nat 'PHOSPHATE ION' 94.971    2   ?       ? ? ? 
8 water       nat water 18.015    537 ?       ? ? ? 
# 
_entity_name_com.entity_id   3 
_entity_name_com.name        'Taq polymerase 1' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 polydeoxyribonucleotide no yes '(DG)(DA)(DC)(DC)(DA)(DC)(DG)(DG)(DC)(DG)(DC)(DOC)' GACCACGGCGCC B,E ? 
2 polydeoxyribonucleotide no yes '(DA)(DA)(DC)(DG)(DG)(DC)(DG)(DC)(DC)(DG)(DT)(DG)(DG)(DT)(DC)(OMG)' AACGGCGCCGTGGTCG C,F ? 
3 'polypeptide(L)'        no no  
;MEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDP
MLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDV
AYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAALEALREAHPIVEKIL
QYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQSIPVRTPLGQRIRRAFIAEEGWLLVALDYSQ
EGLRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVNPLMRRAAKTINFGVLYGMSAHRLSQKLAIPYEEAQAFI
ERYFQSFPKVRAWIEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVRQAAERRAFNMPVQGTAADLMKLAMVKLFPRLE
EMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAKE
;
;MEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDP
MLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDV
AYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAALEALREAHPIVEKIL
QYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQSIPVRTPLGQRIRRAFIAEEGWLLVALDYSQ
EGLRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVNPLMRRAAKTINFGVLYGMSAHRLSQKLAIPYEEAQAFI
ERYFQSFPKVRAWIEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVRQAAERRAFNMPVQGTAADLMKLAMVKLFPRLE
EMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAKE
;
A,D ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 'MAGNESIUM ION' MG    
5 
;[[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
;
A1LWE 
6 'DI(HYDROXYETHYL)ETHER' PEG   
7 'PHOSPHATE ION' PO4   
8 water HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   DG  n 
1 2   DA  n 
1 3   DC  n 
1 4   DC  n 
1 5   DA  n 
1 6   DC  n 
1 7   DG  n 
1 8   DG  n 
1 9   DC  n 
1 10  DG  n 
1 11  DC  n 
1 12  DOC n 
2 1   DA  n 
2 2   DA  n 
2 3   DC  n 
2 4   DG  n 
2 5   DG  n 
2 6   DC  n 
2 7   DG  n 
2 8   DC  n 
2 9   DC  n 
2 10  DG  n 
2 11  DT  n 
2 12  DG  n 
2 13  DG  n 
2 14  DT  n 
2 15  DC  n 
2 16  OMG n 
3 1   MET n 
3 2   GLU n 
3 3   GLU n 
3 4   ALA n 
3 5   PRO n 
3 6   TRP n 
3 7   PRO n 
3 8   PRO n 
3 9   PRO n 
3 10  GLU n 
3 11  GLY n 
3 12  ALA n 
3 13  PHE n 
3 14  VAL n 
3 15  GLY n 
3 16  PHE n 
3 17  VAL n 
3 18  LEU n 
3 19  SER n 
3 20  ARG n 
3 21  LYS n 
3 22  GLU n 
3 23  PRO n 
3 24  MET n 
3 25  TRP n 
3 26  ALA n 
3 27  ASP n 
3 28  LEU n 
3 29  LEU n 
3 30  ALA n 
3 31  LEU n 
3 32  ALA n 
3 33  ALA n 
3 34  ALA n 
3 35  ARG n 
3 36  GLY n 
3 37  GLY n 
3 38  ARG n 
3 39  VAL n 
3 40  HIS n 
3 41  ARG n 
3 42  ALA n 
3 43  PRO n 
3 44  GLU n 
3 45  PRO n 
3 46  TYR n 
3 47  LYS n 
3 48  ALA n 
3 49  LEU n 
3 50  ARG n 
3 51  ASP n 
3 52  LEU n 
3 53  LYS n 
3 54  GLU n 
3 55  ALA n 
3 56  ARG n 
3 57  GLY n 
3 58  LEU n 
3 59  LEU n 
3 60  ALA n 
3 61  LYS n 
3 62  ASP n 
3 63  LEU n 
3 64  SER n 
3 65  VAL n 
3 66  LEU n 
3 67  ALA n 
3 68  LEU n 
3 69  ARG n 
3 70  GLU n 
3 71  GLY n 
3 72  LEU n 
3 73  GLY n 
3 74  LEU n 
3 75  PRO n 
3 76  PRO n 
3 77  GLY n 
3 78  ASP n 
3 79  ASP n 
3 80  PRO n 
3 81  MET n 
3 82  LEU n 
3 83  LEU n 
3 84  ALA n 
3 85  TYR n 
3 86  LEU n 
3 87  LEU n 
3 88  ASP n 
3 89  PRO n 
3 90  SER n 
3 91  ASN n 
3 92  THR n 
3 93  THR n 
3 94  PRO n 
3 95  GLU n 
3 96  GLY n 
3 97  VAL n 
3 98  ALA n 
3 99  ARG n 
3 100 ARG n 
3 101 TYR n 
3 102 GLY n 
3 103 GLY n 
3 104 GLU n 
3 105 TRP n 
3 106 THR n 
3 107 GLU n 
3 108 GLU n 
3 109 ALA n 
3 110 GLY n 
3 111 GLU n 
3 112 ARG n 
3 113 ALA n 
3 114 ALA n 
3 115 LEU n 
3 116 SER n 
3 117 GLU n 
3 118 ARG n 
3 119 LEU n 
3 120 PHE n 
3 121 ALA n 
3 122 ASN n 
3 123 LEU n 
3 124 TRP n 
3 125 GLY n 
3 126 ARG n 
3 127 LEU n 
3 128 GLU n 
3 129 GLY n 
3 130 GLU n 
3 131 GLU n 
3 132 ARG n 
3 133 LEU n 
3 134 LEU n 
3 135 TRP n 
3 136 LEU n 
3 137 TYR n 
3 138 ARG n 
3 139 GLU n 
3 140 VAL n 
3 141 GLU n 
3 142 ARG n 
3 143 PRO n 
3 144 LEU n 
3 145 SER n 
3 146 ALA n 
3 147 VAL n 
3 148 LEU n 
3 149 ALA n 
3 150 HIS n 
3 151 MET n 
3 152 GLU n 
3 153 ALA n 
3 154 THR n 
3 155 GLY n 
3 156 VAL n 
3 157 ARG n 
3 158 LEU n 
3 159 ASP n 
3 160 VAL n 
3 161 ALA n 
3 162 TYR n 
3 163 LEU n 
3 164 ARG n 
3 165 ALA n 
3 166 LEU n 
3 167 SER n 
3 168 LEU n 
3 169 GLU n 
3 170 VAL n 
3 171 ALA n 
3 172 GLU n 
3 173 GLU n 
3 174 ILE n 
3 175 ALA n 
3 176 ARG n 
3 177 LEU n 
3 178 GLU n 
3 179 ALA n 
3 180 GLU n 
3 181 VAL n 
3 182 PHE n 
3 183 ARG n 
3 184 LEU n 
3 185 ALA n 
3 186 GLY n 
3 187 HIS n 
3 188 PRO n 
3 189 PHE n 
3 190 ASN n 
3 191 LEU n 
3 192 ASN n 
3 193 SER n 
3 194 ARG n 
3 195 ASP n 
3 196 GLN n 
3 197 LEU n 
3 198 GLU n 
3 199 ARG n 
3 200 VAL n 
3 201 LEU n 
3 202 PHE n 
3 203 ASP n 
3 204 GLU n 
3 205 LEU n 
3 206 GLY n 
3 207 LEU n 
3 208 PRO n 
3 209 ALA n 
3 210 ILE n 
3 211 GLY n 
3 212 LYS n 
3 213 THR n 
3 214 GLU n 
3 215 LYS n 
3 216 THR n 
3 217 GLY n 
3 218 LYS n 
3 219 ARG n 
3 220 SER n 
3 221 THR n 
3 222 SER n 
3 223 ALA n 
3 224 ALA n 
3 225 ALA n 
3 226 LEU n 
3 227 GLU n 
3 228 ALA n 
3 229 LEU n 
3 230 ARG n 
3 231 GLU n 
3 232 ALA n 
3 233 HIS n 
3 234 PRO n 
3 235 ILE n 
3 236 VAL n 
3 237 GLU n 
3 238 LYS n 
3 239 ILE n 
3 240 LEU n 
3 241 GLN n 
3 242 TYR n 
3 243 ARG n 
3 244 GLU n 
3 245 LEU n 
3 246 THR n 
3 247 LYS n 
3 248 LEU n 
3 249 LYS n 
3 250 SER n 
3 251 THR n 
3 252 TYR n 
3 253 ILE n 
3 254 ASP n 
3 255 PRO n 
3 256 LEU n 
3 257 PRO n 
3 258 ASP n 
3 259 LEU n 
3 260 ILE n 
3 261 HIS n 
3 262 PRO n 
3 263 ARG n 
3 264 THR n 
3 265 GLY n 
3 266 ARG n 
3 267 LEU n 
3 268 HIS n 
3 269 THR n 
3 270 ARG n 
3 271 PHE n 
3 272 ASN n 
3 273 GLN n 
3 274 THR n 
3 275 ALA n 
3 276 THR n 
3 277 ALA n 
3 278 THR n 
3 279 GLY n 
3 280 ARG n 
3 281 LEU n 
3 282 SER n 
3 283 SER n 
3 284 SER n 
3 285 ASP n 
3 286 PRO n 
3 287 ASN n 
3 288 LEU n 
3 289 GLN n 
3 290 SER n 
3 291 ILE n 
3 292 PRO n 
3 293 VAL n 
3 294 ARG n 
3 295 THR n 
3 296 PRO n 
3 297 LEU n 
3 298 GLY n 
3 299 GLN n 
3 300 ARG n 
3 301 ILE n 
3 302 ARG n 
3 303 ARG n 
3 304 ALA n 
3 305 PHE n 
3 306 ILE n 
3 307 ALA n 
3 308 GLU n 
3 309 GLU n 
3 310 GLY n 
3 311 TRP n 
3 312 LEU n 
3 313 LEU n 
3 314 VAL n 
3 315 ALA n 
3 316 LEU n 
3 317 ASP n 
3 318 TYR n 
3 319 SER n 
3 320 GLN n 
3 321 GLU n 
3 322 GLY n 
3 323 LEU n 
3 324 ARG n 
3 325 VAL n 
3 326 LEU n 
3 327 ALA n 
3 328 HIS n 
3 329 LEU n 
3 330 SER n 
3 331 GLY n 
3 332 ASP n 
3 333 GLU n 
3 334 ASN n 
3 335 LEU n 
3 336 ILE n 
3 337 ARG n 
3 338 VAL n 
3 339 PHE n 
3 340 GLN n 
3 341 GLU n 
3 342 GLY n 
3 343 ARG n 
3 344 ASP n 
3 345 ILE n 
3 346 HIS n 
3 347 THR n 
3 348 GLU n 
3 349 THR n 
3 350 ALA n 
3 351 SER n 
3 352 TRP n 
3 353 MET n 
3 354 PHE n 
3 355 GLY n 
3 356 VAL n 
3 357 PRO n 
3 358 ARG n 
3 359 GLU n 
3 360 ALA n 
3 361 VAL n 
3 362 ASN n 
3 363 PRO n 
3 364 LEU n 
3 365 MET n 
3 366 ARG n 
3 367 ARG n 
3 368 ALA n 
3 369 ALA n 
3 370 LYS n 
3 371 THR n 
3 372 ILE n 
3 373 ASN n 
3 374 PHE n 
3 375 GLY n 
3 376 VAL n 
3 377 LEU n 
3 378 TYR n 
3 379 GLY n 
3 380 MET n 
3 381 SER n 
3 382 ALA n 
3 383 HIS n 
3 384 ARG n 
3 385 LEU n 
3 386 SER n 
3 387 GLN n 
3 388 LYS n 
3 389 LEU n 
3 390 ALA n 
3 391 ILE n 
3 392 PRO n 
3 393 TYR n 
3 394 GLU n 
3 395 GLU n 
3 396 ALA n 
3 397 GLN n 
3 398 ALA n 
3 399 PHE n 
3 400 ILE n 
3 401 GLU n 
3 402 ARG n 
3 403 TYR n 
3 404 PHE n 
3 405 GLN n 
3 406 SER n 
3 407 PHE n 
3 408 PRO n 
3 409 LYS n 
3 410 VAL n 
3 411 ARG n 
3 412 ALA n 
3 413 TRP n 
3 414 ILE n 
3 415 GLU n 
3 416 LYS n 
3 417 THR n 
3 418 LEU n 
3 419 GLU n 
3 420 GLU n 
3 421 GLY n 
3 422 ARG n 
3 423 ARG n 
3 424 ARG n 
3 425 GLY n 
3 426 TYR n 
3 427 VAL n 
3 428 GLU n 
3 429 THR n 
3 430 LEU n 
3 431 PHE n 
3 432 GLY n 
3 433 ARG n 
3 434 ARG n 
3 435 ARG n 
3 436 TYR n 
3 437 VAL n 
3 438 PRO n 
3 439 ASP n 
3 440 LEU n 
3 441 GLU n 
3 442 ALA n 
3 443 ARG n 
3 444 VAL n 
3 445 LYS n 
3 446 SER n 
3 447 VAL n 
3 448 ARG n 
3 449 GLN n 
3 450 ALA n 
3 451 ALA n 
3 452 GLU n 
3 453 ARG n 
3 454 ARG n 
3 455 ALA n 
3 456 PHE n 
3 457 ASN n 
3 458 MET n 
3 459 PRO n 
3 460 VAL n 
3 461 GLN n 
3 462 GLY n 
3 463 THR n 
3 464 ALA n 
3 465 ALA n 
3 466 ASP n 
3 467 LEU n 
3 468 MET n 
3 469 LYS n 
3 470 LEU n 
3 471 ALA n 
3 472 MET n 
3 473 VAL n 
3 474 LYS n 
3 475 LEU n 
3 476 PHE n 
3 477 PRO n 
3 478 ARG n 
3 479 LEU n 
3 480 GLU n 
3 481 GLU n 
3 482 MET n 
3 483 GLY n 
3 484 ALA n 
3 485 ARG n 
3 486 MET n 
3 487 LEU n 
3 488 LEU n 
3 489 GLN n 
3 490 VAL n 
3 491 HIS n 
3 492 ASP n 
3 493 GLU n 
3 494 LEU n 
3 495 VAL n 
3 496 LEU n 
3 497 GLU n 
3 498 ALA n 
3 499 PRO n 
3 500 LYS n 
3 501 GLU n 
3 502 ARG n 
3 503 ALA n 
3 504 GLU n 
3 505 ALA n 
3 506 VAL n 
3 507 ALA n 
3 508 ARG n 
3 509 LEU n 
3 510 ALA n 
3 511 LYS n 
3 512 GLU n 
3 513 VAL n 
3 514 MET n 
3 515 GLU n 
3 516 GLY n 
3 517 VAL n 
3 518 TYR n 
3 519 PRO n 
3 520 LEU n 
3 521 ALA n 
3 522 VAL n 
3 523 PRO n 
3 524 LEU n 
3 525 GLU n 
3 526 VAL n 
3 527 GLU n 
3 528 VAL n 
3 529 GLY n 
3 530 ILE n 
3 531 GLY n 
3 532 GLU n 
3 533 ASP n 
3 534 TRP n 
3 535 LEU n 
3 536 SER n 
3 537 ALA n 
3 538 LYS n 
3 539 GLU n 
# 
_entity_src_gen.entity_id                          3 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   539 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'polA, pol1' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Thermus aquaticus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     271 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_pdbx_entity_src_syn.entity_id 
_pdbx_entity_src_syn.pdbx_src_id 
_pdbx_entity_src_syn.pdbx_alt_source_flag 
_pdbx_entity_src_syn.pdbx_beg_seq_num 
_pdbx_entity_src_syn.pdbx_end_seq_num 
_pdbx_entity_src_syn.organism_scientific 
_pdbx_entity_src_syn.organism_common_name 
_pdbx_entity_src_syn.ncbi_taxonomy_id 
_pdbx_entity_src_syn.details 
1 1 sample 1 12 'synthetic construct' ? 32630 ? 
2 1 sample 1 16 'synthetic construct' ? 32630 ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1LWE non-polymer         . 
;[[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
;
? 'C11 H18 N5 O14 P3' 537.207 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'        89.093  
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1'    175.209 
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'       132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'        133.103 
DA    'DNA linking'       y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O6 P'   331.222 
DC    'DNA linking'       y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE" ? 'C9 H14 N3 O7 P'    307.197 
DG    'DNA linking'       y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P'   347.221 
DOC   'DNA linking'       n "2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE" ? 'C9 H14 N3 O6 P'    291.198 
DT    'DNA linking'       y "THYMIDINE-5'-MONOPHOSPHATE" ? 'C10 H15 N2 O8 P'   322.208 
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'      146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'        147.129 
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'        75.067  
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1'    156.162 
HOH   non-polymer         . WATER ? 'H2 O'              18.015  
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'       131.173 
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'       131.173 
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1'    147.195 
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'     149.211 
MG    non-polymer         . 'MAGNESIUM ION' ? 'Mg 2'              24.305  
OMG   'RNA linking'       n "O2'-METHYLGUANOSINE-5'-MONOPHOSPHATE" ? 'C11 H16 N5 O8 P'   377.247 
PEG   non-polymer         . 'DI(HYDROXYETHYL)ETHER' ? 'C4 H10 O3'         106.120 
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'       165.189 
PO4   non-polymer         . 'PHOSPHATE ION' ? 'O4 P -3'           94.971  
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'        115.130 
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'        105.093 
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'        119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'     204.225 
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'       181.189 
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   DG  1   101 101 DG  DG  B . n 
A 1 2   DA  2   102 102 DA  DA  B . n 
A 1 3   DC  3   103 103 DC  DC  B . n 
A 1 4   DC  4   104 104 DC  DC  B . n 
A 1 5   DA  5   105 105 DA  DA  B . n 
A 1 6   DC  6   106 106 DC  DC  B . n 
A 1 7   DG  7   107 107 DG  DG  B . n 
A 1 8   DG  8   108 108 DG  DG  B . n 
A 1 9   DC  9   109 109 DC  DC  B . n 
A 1 10  DG  10  110 110 DG  DG  B . n 
A 1 11  DC  11  111 111 DC  DC  B . n 
A 1 12  DOC 12  112 112 DOC DOC B . n 
B 2 1   DA  1   202 202 DA  DA  C . n 
B 2 2   DA  2   203 203 DA  DA  C . n 
B 2 3   DC  3   204 204 DC  DC  C . n 
B 2 4   DG  4   205 205 DG  DG  C . n 
B 2 5   DG  5   206 206 DG  DG  C . n 
B 2 6   DC  6   207 207 DC  DC  C . n 
B 2 7   DG  7   208 208 DG  DG  C . n 
B 2 8   DC  8   209 209 DC  DC  C . n 
B 2 9   DC  9   210 210 DC  DC  C . n 
B 2 10  DG  10  211 211 DG  DG  C . n 
B 2 11  DT  11  212 212 DT  DT  C . n 
B 2 12  DG  12  213 213 DG  DG  C . n 
B 2 13  DG  13  214 214 DG  DG  C . n 
B 2 14  DT  14  215 215 DT  DT  C . n 
B 2 15  DC  15  216 216 DC  DC  C . n 
B 2 16  OMG 16  217 217 OMG OMG C . n 
C 3 1   MET 1   294 ?   ?   ?   A . n 
C 3 2   GLU 2   295 ?   ?   ?   A . n 
C 3 3   GLU 3   296 296 GLU GLU A . n 
C 3 4   ALA 4   297 297 ALA ALA A . n 
C 3 5   PRO 5   298 298 PRO PRO A . n 
C 3 6   TRP 6   299 299 TRP TRP A . n 
C 3 7   PRO 7   300 300 PRO PRO A . n 
C 3 8   PRO 8   301 301 PRO PRO A . n 
C 3 9   PRO 9   302 302 PRO PRO A . n 
C 3 10  GLU 10  303 303 GLU GLU A . n 
C 3 11  GLY 11  304 304 GLY GLY A . n 
C 3 12  ALA 12  305 305 ALA ALA A . n 
C 3 13  PHE 13  306 306 PHE PHE A . n 
C 3 14  VAL 14  307 307 VAL VAL A . n 
C 3 15  GLY 15  308 308 GLY GLY A . n 
C 3 16  PHE 16  309 309 PHE PHE A . n 
C 3 17  VAL 17  310 310 VAL VAL A . n 
C 3 18  LEU 18  311 311 LEU LEU A . n 
C 3 19  SER 19  312 312 SER SER A . n 
C 3 20  ARG 20  313 313 ARG ARG A . n 
C 3 21  LYS 21  314 314 LYS LYS A . n 
C 3 22  GLU 22  315 315 GLU GLU A . n 
C 3 23  PRO 23  316 316 PRO PRO A . n 
C 3 24  MET 24  317 317 MET MET A . n 
C 3 25  TRP 25  318 318 TRP TRP A . n 
C 3 26  ALA 26  319 319 ALA ALA A . n 
C 3 27  ASP 27  320 320 ASP ASP A . n 
C 3 28  LEU 28  321 321 LEU LEU A . n 
C 3 29  LEU 29  322 322 LEU LEU A . n 
C 3 30  ALA 30  323 323 ALA ALA A . n 
C 3 31  LEU 31  324 324 LEU LEU A . n 
C 3 32  ALA 32  325 325 ALA ALA A . n 
C 3 33  ALA 33  326 326 ALA ALA A . n 
C 3 34  ALA 34  327 327 ALA ALA A . n 
C 3 35  ARG 35  328 328 ARG ARG A . n 
C 3 36  GLY 36  329 329 GLY GLY A . n 
C 3 37  GLY 37  330 330 GLY GLY A . n 
C 3 38  ARG 38  331 331 ARG ARG A . n 
C 3 39  VAL 39  332 332 VAL VAL A . n 
C 3 40  HIS 40  333 333 HIS HIS A . n 
C 3 41  ARG 41  334 334 ARG ARG A . n 
C 3 42  ALA 42  335 335 ALA ALA A . n 
C 3 43  PRO 43  336 336 PRO PRO A . n 
C 3 44  GLU 44  337 337 GLU GLU A . n 
C 3 45  PRO 45  338 338 PRO PRO A . n 
C 3 46  TYR 46  339 339 TYR TYR A . n 
C 3 47  LYS 47  340 340 LYS LYS A . n 
C 3 48  ALA 48  341 341 ALA ALA A . n 
C 3 49  LEU 49  342 342 LEU LEU A . n 
C 3 50  ARG 50  343 343 ARG ARG A . n 
C 3 51  ASP 51  344 344 ASP ASP A . n 
C 3 52  LEU 52  345 345 LEU LEU A . n 
C 3 53  LYS 53  346 346 LYS LYS A . n 
C 3 54  GLU 54  347 347 GLU GLU A . n 
C 3 55  ALA 55  348 348 ALA ALA A . n 
C 3 56  ARG 56  349 349 ARG ARG A . n 
C 3 57  GLY 57  350 350 GLY GLY A . n 
C 3 58  LEU 58  351 351 LEU LEU A . n 
C 3 59  LEU 59  352 352 LEU LEU A . n 
C 3 60  ALA 60  353 353 ALA ALA A . n 
C 3 61  LYS 61  354 354 LYS LYS A . n 
C 3 62  ASP 62  355 355 ASP ASP A . n 
C 3 63  LEU 63  356 356 LEU LEU A . n 
C 3 64  SER 64  357 357 SER SER A . n 
C 3 65  VAL 65  358 358 VAL VAL A . n 
C 3 66  LEU 66  359 359 LEU LEU A . n 
C 3 67  ALA 67  360 360 ALA ALA A . n 
C 3 68  LEU 68  361 361 LEU LEU A . n 
C 3 69  ARG 69  362 362 ARG ARG A . n 
C 3 70  GLU 70  363 363 GLU GLU A . n 
C 3 71  GLY 71  364 364 GLY GLY A . n 
C 3 72  LEU 72  365 365 LEU LEU A . n 
C 3 73  GLY 73  366 366 GLY GLY A . n 
C 3 74  LEU 74  367 367 LEU LEU A . n 
C 3 75  PRO 75  368 368 PRO PRO A . n 
C 3 76  PRO 76  369 369 PRO PRO A . n 
C 3 77  GLY 77  370 370 GLY GLY A . n 
C 3 78  ASP 78  371 371 ASP ASP A . n 
C 3 79  ASP 79  372 372 ASP ASP A . n 
C 3 80  PRO 80  373 373 PRO PRO A . n 
C 3 81  MET 81  374 374 MET MET A . n 
C 3 82  LEU 82  375 375 LEU LEU A . n 
C 3 83  LEU 83  376 376 LEU LEU A . n 
C 3 84  ALA 84  377 377 ALA ALA A . n 
C 3 85  TYR 85  378 378 TYR TYR A . n 
C 3 86  LEU 86  379 379 LEU LEU A . n 
C 3 87  LEU 87  380 380 LEU LEU A . n 
C 3 88  ASP 88  381 381 ASP ASP A . n 
C 3 89  PRO 89  382 382 PRO PRO A . n 
C 3 90  SER 90  383 383 SER SER A . n 
C 3 91  ASN 91  384 384 ASN ASN A . n 
C 3 92  THR 92  385 385 THR THR A . n 
C 3 93  THR 93  386 386 THR THR A . n 
C 3 94  PRO 94  387 387 PRO PRO A . n 
C 3 95  GLU 95  388 388 GLU GLU A . n 
C 3 96  GLY 96  389 389 GLY GLY A . n 
C 3 97  VAL 97  390 390 VAL VAL A . n 
C 3 98  ALA 98  391 391 ALA ALA A . n 
C 3 99  ARG 99  392 392 ARG ARG A . n 
C 3 100 ARG 100 393 393 ARG ARG A . n 
C 3 101 TYR 101 394 394 TYR TYR A . n 
C 3 102 GLY 102 395 395 GLY GLY A . n 
C 3 103 GLY 103 396 396 GLY GLY A . n 
C 3 104 GLU 104 397 397 GLU GLU A . n 
C 3 105 TRP 105 398 398 TRP TRP A . n 
C 3 106 THR 106 399 399 THR THR A . n 
C 3 107 GLU 107 400 400 GLU GLU A . n 
C 3 108 GLU 108 401 401 GLU GLU A . n 
C 3 109 ALA 109 402 402 ALA ALA A . n 
C 3 110 GLY 110 403 403 GLY GLY A . n 
C 3 111 GLU 111 404 404 GLU GLU A . n 
C 3 112 ARG 112 405 405 ARG ARG A . n 
C 3 113 ALA 113 406 406 ALA ALA A . n 
C 3 114 ALA 114 407 407 ALA ALA A . n 
C 3 115 LEU 115 408 408 LEU LEU A . n 
C 3 116 SER 116 409 409 SER SER A . n 
C 3 117 GLU 117 410 410 GLU GLU A . n 
C 3 118 ARG 118 411 411 ARG ARG A . n 
C 3 119 LEU 119 412 412 LEU LEU A . n 
C 3 120 PHE 120 413 413 PHE PHE A . n 
C 3 121 ALA 121 414 414 ALA ALA A . n 
C 3 122 ASN 122 415 415 ASN ASN A . n 
C 3 123 LEU 123 416 416 LEU LEU A . n 
C 3 124 TRP 124 417 417 TRP TRP A . n 
C 3 125 GLY 125 418 418 GLY GLY A . n 
C 3 126 ARG 126 419 419 ARG ARG A . n 
C 3 127 LEU 127 420 420 LEU LEU A . n 
C 3 128 GLU 128 421 421 GLU GLU A . n 
C 3 129 GLY 129 422 422 GLY GLY A . n 
C 3 130 GLU 130 423 423 GLU GLU A . n 
C 3 131 GLU 131 424 424 GLU GLU A . n 
C 3 132 ARG 132 425 425 ARG ARG A . n 
C 3 133 LEU 133 426 426 LEU LEU A . n 
C 3 134 LEU 134 427 427 LEU LEU A . n 
C 3 135 TRP 135 428 428 TRP TRP A . n 
C 3 136 LEU 136 429 429 LEU LEU A . n 
C 3 137 TYR 137 430 430 TYR TYR A . n 
C 3 138 ARG 138 431 431 ARG ARG A . n 
C 3 139 GLU 139 432 432 GLU GLU A . n 
C 3 140 VAL 140 433 433 VAL VAL A . n 
C 3 141 GLU 141 434 434 GLU GLU A . n 
C 3 142 ARG 142 435 435 ARG ARG A . n 
C 3 143 PRO 143 436 436 PRO PRO A . n 
C 3 144 LEU 144 437 437 LEU LEU A . n 
C 3 145 SER 145 438 438 SER SER A . n 
C 3 146 ALA 146 439 439 ALA ALA A . n 
C 3 147 VAL 147 440 440 VAL VAL A . n 
C 3 148 LEU 148 441 441 LEU LEU A . n 
C 3 149 ALA 149 442 442 ALA ALA A . n 
C 3 150 HIS 150 443 443 HIS HIS A . n 
C 3 151 MET 151 444 444 MET MET A . n 
C 3 152 GLU 152 445 445 GLU GLU A . n 
C 3 153 ALA 153 446 446 ALA ALA A . n 
C 3 154 THR 154 447 447 THR THR A . n 
C 3 155 GLY 155 448 448 GLY GLY A . n 
C 3 156 VAL 156 449 449 VAL VAL A . n 
C 3 157 ARG 157 450 450 ARG ARG A . n 
C 3 158 LEU 158 451 451 LEU LEU A . n 
C 3 159 ASP 159 452 452 ASP ASP A . n 
C 3 160 VAL 160 453 453 VAL VAL A . n 
C 3 161 ALA 161 454 454 ALA ALA A . n 
C 3 162 TYR 162 455 455 TYR TYR A . n 
C 3 163 LEU 163 456 456 LEU LEU A . n 
C 3 164 ARG 164 457 457 ARG ARG A . n 
C 3 165 ALA 165 458 458 ALA ALA A . n 
C 3 166 LEU 166 459 459 LEU LEU A . n 
C 3 167 SER 167 460 460 SER SER A . n 
C 3 168 LEU 168 461 461 LEU LEU A . n 
C 3 169 GLU 169 462 462 GLU GLU A . n 
C 3 170 VAL 170 463 463 VAL VAL A . n 
C 3 171 ALA 171 464 464 ALA ALA A . n 
C 3 172 GLU 172 465 465 GLU GLU A . n 
C 3 173 GLU 173 466 466 GLU GLU A . n 
C 3 174 ILE 174 467 467 ILE ILE A . n 
C 3 175 ALA 175 468 468 ALA ALA A . n 
C 3 176 ARG 176 469 469 ARG ARG A . n 
C 3 177 LEU 177 470 470 LEU LEU A . n 
C 3 178 GLU 178 471 471 GLU GLU A . n 
C 3 179 ALA 179 472 472 ALA ALA A . n 
C 3 180 GLU 180 473 473 GLU GLU A . n 
C 3 181 VAL 181 474 474 VAL VAL A . n 
C 3 182 PHE 182 475 475 PHE PHE A . n 
C 3 183 ARG 183 476 476 ARG ARG A . n 
C 3 184 LEU 184 477 477 LEU LEU A . n 
C 3 185 ALA 185 478 478 ALA ALA A . n 
C 3 186 GLY 186 479 479 GLY GLY A . n 
C 3 187 HIS 187 480 480 HIS HIS A . n 
C 3 188 PRO 188 481 481 PRO PRO A . n 
C 3 189 PHE 189 482 482 PHE PHE A . n 
C 3 190 ASN 190 483 483 ASN ASN A . n 
C 3 191 LEU 191 484 484 LEU LEU A . n 
C 3 192 ASN 192 485 485 ASN ASN A . n 
C 3 193 SER 193 486 486 SER SER A . n 
C 3 194 ARG 194 487 487 ARG ARG A . n 
C 3 195 ASP 195 488 488 ASP ASP A . n 
C 3 196 GLN 196 489 489 GLN GLN A . n 
C 3 197 LEU 197 490 490 LEU LEU A . n 
C 3 198 GLU 198 491 491 GLU GLU A . n 
C 3 199 ARG 199 492 492 ARG ARG A . n 
C 3 200 VAL 200 493 493 VAL VAL A . n 
C 3 201 LEU 201 494 494 LEU LEU A . n 
C 3 202 PHE 202 495 495 PHE PHE A . n 
C 3 203 ASP 203 496 496 ASP ASP A . n 
C 3 204 GLU 204 497 497 GLU GLU A . n 
C 3 205 LEU 205 498 498 LEU LEU A . n 
C 3 206 GLY 206 499 499 GLY GLY A . n 
C 3 207 LEU 207 500 500 LEU LEU A . n 
C 3 208 PRO 208 501 501 PRO PRO A . n 
C 3 209 ALA 209 502 502 ALA ALA A . n 
C 3 210 ILE 210 503 503 ILE ILE A . n 
C 3 211 GLY 211 504 504 GLY GLY A . n 
C 3 212 LYS 212 505 505 LYS LYS A . n 
C 3 213 THR 213 506 506 THR THR A . n 
C 3 214 GLU 214 507 507 GLU GLU A . n 
C 3 215 LYS 215 508 508 LYS LYS A . n 
C 3 216 THR 216 509 509 THR THR A . n 
C 3 217 GLY 217 510 510 GLY GLY A . n 
C 3 218 LYS 218 511 511 LYS LYS A . n 
C 3 219 ARG 219 512 512 ARG ARG A . n 
C 3 220 SER 220 513 513 SER SER A . n 
C 3 221 THR 221 514 514 THR THR A . n 
C 3 222 SER 222 515 515 SER SER A . n 
C 3 223 ALA 223 516 516 ALA ALA A . n 
C 3 224 ALA 224 517 517 ALA ALA A . n 
C 3 225 ALA 225 518 518 ALA ALA A . n 
C 3 226 LEU 226 519 519 LEU LEU A . n 
C 3 227 GLU 227 520 520 GLU GLU A . n 
C 3 228 ALA 228 521 521 ALA ALA A . n 
C 3 229 LEU 229 522 522 LEU LEU A . n 
C 3 230 ARG 230 523 523 ARG ARG A . n 
C 3 231 GLU 231 524 524 GLU GLU A . n 
C 3 232 ALA 232 525 525 ALA ALA A . n 
C 3 233 HIS 233 526 526 HIS HIS A . n 
C 3 234 PRO 234 527 527 PRO PRO A . n 
C 3 235 ILE 235 528 528 ILE ILE A . n 
C 3 236 VAL 236 529 529 VAL VAL A . n 
C 3 237 GLU 237 530 530 GLU GLU A . n 
C 3 238 LYS 238 531 531 LYS LYS A . n 
C 3 239 ILE 239 532 532 ILE ILE A . n 
C 3 240 LEU 240 533 533 LEU LEU A . n 
C 3 241 GLN 241 534 534 GLN GLN A . n 
C 3 242 TYR 242 535 535 TYR TYR A . n 
C 3 243 ARG 243 536 536 ARG ARG A . n 
C 3 244 GLU 244 537 537 GLU GLU A . n 
C 3 245 LEU 245 538 538 LEU LEU A . n 
C 3 246 THR 246 539 539 THR THR A . n 
C 3 247 LYS 247 540 540 LYS LYS A . n 
C 3 248 LEU 248 541 541 LEU LEU A . n 
C 3 249 LYS 249 542 542 LYS LYS A . n 
C 3 250 SER 250 543 543 SER SER A . n 
C 3 251 THR 251 544 544 THR THR A . n 
C 3 252 TYR 252 545 545 TYR TYR A . n 
C 3 253 ILE 253 546 546 ILE ILE A . n 
C 3 254 ASP 254 547 547 ASP ASP A . n 
C 3 255 PRO 255 548 548 PRO PRO A . n 
C 3 256 LEU 256 549 549 LEU LEU A . n 
C 3 257 PRO 257 550 550 PRO PRO A . n 
C 3 258 ASP 258 551 551 ASP ASP A . n 
C 3 259 LEU 259 552 552 LEU LEU A . n 
C 3 260 ILE 260 553 553 ILE ILE A . n 
C 3 261 HIS 261 554 554 HIS HIS A . n 
C 3 262 PRO 262 555 555 PRO PRO A . n 
C 3 263 ARG 263 556 556 ARG ARG A . n 
C 3 264 THR 264 557 557 THR THR A . n 
C 3 265 GLY 265 558 558 GLY GLY A . n 
C 3 266 ARG 266 559 559 ARG ARG A . n 
C 3 267 LEU 267 560 560 LEU LEU A . n 
C 3 268 HIS 268 561 561 HIS HIS A . n 
C 3 269 THR 269 562 562 THR THR A . n 
C 3 270 ARG 270 563 563 ARG ARG A . n 
C 3 271 PHE 271 564 564 PHE PHE A . n 
C 3 272 ASN 272 565 565 ASN ASN A . n 
C 3 273 GLN 273 566 566 GLN GLN A . n 
C 3 274 THR 274 567 567 THR THR A . n 
C 3 275 ALA 275 568 568 ALA ALA A . n 
C 3 276 THR 276 569 569 THR THR A . n 
C 3 277 ALA 277 570 570 ALA ALA A . n 
C 3 278 THR 278 571 571 THR THR A . n 
C 3 279 GLY 279 572 572 GLY GLY A . n 
C 3 280 ARG 280 573 573 ARG ARG A . n 
C 3 281 LEU 281 574 574 LEU LEU A . n 
C 3 282 SER 282 575 575 SER SER A . n 
C 3 283 SER 283 576 576 SER SER A . n 
C 3 284 SER 284 577 577 SER SER A . n 
C 3 285 ASP 285 578 578 ASP ASP A . n 
C 3 286 PRO 286 579 579 PRO PRO A . n 
C 3 287 ASN 287 580 580 ASN ASN A . n 
C 3 288 LEU 288 581 581 LEU LEU A . n 
C 3 289 GLN 289 582 582 GLN GLN A . n 
C 3 290 SER 290 583 583 SER SER A . n 
C 3 291 ILE 291 584 584 ILE ILE A . n 
C 3 292 PRO 292 585 585 PRO PRO A . n 
C 3 293 VAL 293 586 586 VAL VAL A . n 
C 3 294 ARG 294 587 587 ARG ARG A . n 
C 3 295 THR 295 588 588 THR THR A . n 
C 3 296 PRO 296 589 589 PRO PRO A . n 
C 3 297 LEU 297 590 590 LEU LEU A . n 
C 3 298 GLY 298 591 591 GLY GLY A . n 
C 3 299 GLN 299 592 592 GLN GLN A . n 
C 3 300 ARG 300 593 593 ARG ARG A . n 
C 3 301 ILE 301 594 594 ILE ILE A . n 
C 3 302 ARG 302 595 595 ARG ARG A . n 
C 3 303 ARG 303 596 596 ARG ARG A . n 
C 3 304 ALA 304 597 597 ALA ALA A . n 
C 3 305 PHE 305 598 598 PHE PHE A . n 
C 3 306 ILE 306 599 599 ILE ILE A . n 
C 3 307 ALA 307 600 600 ALA ALA A . n 
C 3 308 GLU 308 601 601 GLU GLU A . n 
C 3 309 GLU 309 602 602 GLU GLU A . n 
C 3 310 GLY 310 603 603 GLY GLY A . n 
C 3 311 TRP 311 604 604 TRP TRP A . n 
C 3 312 LEU 312 605 605 LEU LEU A . n 
C 3 313 LEU 313 606 606 LEU LEU A . n 
C 3 314 VAL 314 607 607 VAL VAL A . n 
C 3 315 ALA 315 608 608 ALA ALA A . n 
C 3 316 LEU 316 609 609 LEU LEU A . n 
C 3 317 ASP 317 610 610 ASP ASP A . n 
C 3 318 TYR 318 611 611 TYR TYR A . n 
C 3 319 SER 319 612 612 SER SER A . n 
C 3 320 GLN 320 613 613 GLN GLN A . n 
C 3 321 GLU 321 614 614 GLU GLU A . n 
C 3 322 GLY 322 615 615 GLY GLY A . n 
C 3 323 LEU 323 616 616 LEU LEU A . n 
C 3 324 ARG 324 617 617 ARG ARG A . n 
C 3 325 VAL 325 618 618 VAL VAL A . n 
C 3 326 LEU 326 619 619 LEU LEU A . n 
C 3 327 ALA 327 620 620 ALA ALA A . n 
C 3 328 HIS 328 621 621 HIS HIS A . n 
C 3 329 LEU 329 622 622 LEU LEU A . n 
C 3 330 SER 330 623 623 SER SER A . n 
C 3 331 GLY 331 624 624 GLY GLY A . n 
C 3 332 ASP 332 625 625 ASP ASP A . n 
C 3 333 GLU 333 626 626 GLU GLU A . n 
C 3 334 ASN 334 627 627 ASN ASN A . n 
C 3 335 LEU 335 628 628 LEU LEU A . n 
C 3 336 ILE 336 629 629 ILE ILE A . n 
C 3 337 ARG 337 630 630 ARG ARG A . n 
C 3 338 VAL 338 631 631 VAL VAL A . n 
C 3 339 PHE 339 632 632 PHE PHE A . n 
C 3 340 GLN 340 633 633 GLN GLN A . n 
C 3 341 GLU 341 634 634 GLU GLU A . n 
C 3 342 GLY 342 635 635 GLY GLY A . n 
C 3 343 ARG 343 636 636 ARG ARG A . n 
C 3 344 ASP 344 637 637 ASP ASP A . n 
C 3 345 ILE 345 638 638 ILE ILE A . n 
C 3 346 HIS 346 639 639 HIS HIS A . n 
C 3 347 THR 347 640 640 THR THR A . n 
C 3 348 GLU 348 641 641 GLU GLU A . n 
C 3 349 THR 349 642 642 THR THR A . n 
C 3 350 ALA 350 643 643 ALA ALA A . n 
C 3 351 SER 351 644 644 SER SER A . n 
C 3 352 TRP 352 645 645 TRP TRP A . n 
C 3 353 MET 353 646 646 MET MET A . n 
C 3 354 PHE 354 647 647 PHE PHE A . n 
C 3 355 GLY 355 648 648 GLY GLY A . n 
C 3 356 VAL 356 649 649 VAL VAL A . n 
C 3 357 PRO 357 650 650 PRO PRO A . n 
C 3 358 ARG 358 651 651 ARG ARG A . n 
C 3 359 GLU 359 652 652 GLU GLU A . n 
C 3 360 ALA 360 653 653 ALA ALA A . n 
C 3 361 VAL 361 654 654 VAL VAL A . n 
C 3 362 ASN 362 655 655 ASN ASN A . n 
C 3 363 PRO 363 656 656 PRO PRO A . n 
C 3 364 LEU 364 657 657 LEU LEU A . n 
C 3 365 MET 365 658 658 MET MET A . n 
C 3 366 ARG 366 659 659 ARG ARG A . n 
C 3 367 ARG 367 660 660 ARG ARG A . n 
C 3 368 ALA 368 661 661 ALA ALA A . n 
C 3 369 ALA 369 662 662 ALA ALA A . n 
C 3 370 LYS 370 663 663 LYS LYS A . n 
C 3 371 THR 371 664 664 THR THR A . n 
C 3 372 ILE 372 665 665 ILE ILE A . n 
C 3 373 ASN 373 666 666 ASN ASN A . n 
C 3 374 PHE 374 667 667 PHE PHE A . n 
C 3 375 GLY 375 668 668 GLY GLY A . n 
C 3 376 VAL 376 669 669 VAL VAL A . n 
C 3 377 LEU 377 670 670 LEU LEU A . n 
C 3 378 TYR 378 671 671 TYR TYR A . n 
C 3 379 GLY 379 672 672 GLY GLY A . n 
C 3 380 MET 380 673 673 MET MET A . n 
C 3 381 SER 381 674 674 SER SER A . n 
C 3 382 ALA 382 675 675 ALA ALA A . n 
C 3 383 HIS 383 676 676 HIS HIS A . n 
C 3 384 ARG 384 677 677 ARG ARG A . n 
C 3 385 LEU 385 678 678 LEU LEU A . n 
C 3 386 SER 386 679 679 SER SER A . n 
C 3 387 GLN 387 680 680 GLN GLN A . n 
C 3 388 LYS 388 681 681 LYS LYS A . n 
C 3 389 LEU 389 682 682 LEU LEU A . n 
C 3 390 ALA 390 683 683 ALA ALA A . n 
C 3 391 ILE 391 684 684 ILE ILE A . n 
C 3 392 PRO 392 685 685 PRO PRO A . n 
C 3 393 TYR 393 686 686 TYR TYR A . n 
C 3 394 GLU 394 687 687 GLU GLU A . n 
C 3 395 GLU 395 688 688 GLU GLU A . n 
C 3 396 ALA 396 689 689 ALA ALA A . n 
C 3 397 GLN 397 690 690 GLN GLN A . n 
C 3 398 ALA 398 691 691 ALA ALA A . n 
C 3 399 PHE 399 692 692 PHE PHE A . n 
C 3 400 ILE 400 693 693 ILE ILE A . n 
C 3 401 GLU 401 694 694 GLU GLU A . n 
C 3 402 ARG 402 695 695 ARG ARG A . n 
C 3 403 TYR 403 696 696 TYR TYR A . n 
C 3 404 PHE 404 697 697 PHE PHE A . n 
C 3 405 GLN 405 698 698 GLN GLN A . n 
C 3 406 SER 406 699 699 SER SER A . n 
C 3 407 PHE 407 700 700 PHE PHE A . n 
C 3 408 PRO 408 701 701 PRO PRO A . n 
C 3 409 LYS 409 702 702 LYS LYS A . n 
C 3 410 VAL 410 703 703 VAL VAL A . n 
C 3 411 ARG 411 704 704 ARG ARG A . n 
C 3 412 ALA 412 705 705 ALA ALA A . n 
C 3 413 TRP 413 706 706 TRP TRP A . n 
C 3 414 ILE 414 707 707 ILE ILE A . n 
C 3 415 GLU 415 708 708 GLU GLU A . n 
C 3 416 LYS 416 709 709 LYS LYS A . n 
C 3 417 THR 417 710 710 THR THR A . n 
C 3 418 LEU 418 711 711 LEU LEU A . n 
C 3 419 GLU 419 712 712 GLU GLU A . n 
C 3 420 GLU 420 713 713 GLU GLU A . n 
C 3 421 GLY 421 714 714 GLY GLY A . n 
C 3 422 ARG 422 715 715 ARG ARG A . n 
C 3 423 ARG 423 716 716 ARG ARG A . n 
C 3 424 ARG 424 717 717 ARG ARG A . n 
C 3 425 GLY 425 718 718 GLY GLY A . n 
C 3 426 TYR 426 719 719 TYR TYR A . n 
C 3 427 VAL 427 720 720 VAL VAL A . n 
C 3 428 GLU 428 721 721 GLU GLU A . n 
C 3 429 THR 429 722 722 THR THR A . n 
C 3 430 LEU 430 723 723 LEU LEU A . n 
C 3 431 PHE 431 724 724 PHE PHE A . n 
C 3 432 GLY 432 725 725 GLY GLY A . n 
C 3 433 ARG 433 726 726 ARG ARG A . n 
C 3 434 ARG 434 727 727 ARG ARG A . n 
C 3 435 ARG 435 728 728 ARG ARG A . n 
C 3 436 TYR 436 729 729 TYR TYR A . n 
C 3 437 VAL 437 730 730 VAL VAL A . n 
C 3 438 PRO 438 731 731 PRO PRO A . n 
C 3 439 ASP 439 732 732 ASP ASP A . n 
C 3 440 LEU 440 733 733 LEU LEU A . n 
C 3 441 GLU 441 734 734 GLU GLU A . n 
C 3 442 ALA 442 735 735 ALA ALA A . n 
C 3 443 ARG 443 736 736 ARG ARG A . n 
C 3 444 VAL 444 737 737 VAL VAL A . n 
C 3 445 LYS 445 738 738 LYS LYS A . n 
C 3 446 SER 446 739 739 SER SER A . n 
C 3 447 VAL 447 740 740 VAL VAL A . n 
C 3 448 ARG 448 741 741 ARG ARG A . n 
C 3 449 GLN 449 742 742 GLN GLN A . n 
C 3 450 ALA 450 743 743 ALA ALA A . n 
C 3 451 ALA 451 744 744 ALA ALA A . n 
C 3 452 GLU 452 745 745 GLU GLU A . n 
C 3 453 ARG 453 746 746 ARG ARG A . n 
C 3 454 ARG 454 747 747 ARG ARG A . n 
C 3 455 ALA 455 748 748 ALA ALA A . n 
C 3 456 PHE 456 749 749 PHE PHE A . n 
C 3 457 ASN 457 750 750 ASN ASN A . n 
C 3 458 MET 458 751 751 MET MET A . n 
C 3 459 PRO 459 752 752 PRO PRO A . n 
C 3 460 VAL 460 753 753 VAL VAL A . n 
C 3 461 GLN 461 754 754 GLN GLN A . n 
C 3 462 GLY 462 755 755 GLY GLY A . n 
C 3 463 THR 463 756 756 THR THR A . n 
C 3 464 ALA 464 757 757 ALA ALA A . n 
C 3 465 ALA 465 758 758 ALA ALA A . n 
C 3 466 ASP 466 759 759 ASP ASP A . n 
C 3 467 LEU 467 760 760 LEU LEU A . n 
C 3 468 MET 468 761 761 MET MET A . n 
C 3 469 LYS 469 762 762 LYS LYS A . n 
C 3 470 LEU 470 763 763 LEU LEU A . n 
C 3 471 ALA 471 764 764 ALA ALA A . n 
C 3 472 MET 472 765 765 MET MET A . n 
C 3 473 VAL 473 766 766 VAL VAL A . n 
C 3 474 LYS 474 767 767 LYS LYS A . n 
C 3 475 LEU 475 768 768 LEU LEU A . n 
C 3 476 PHE 476 769 769 PHE PHE A . n 
C 3 477 PRO 477 770 770 PRO PRO A . n 
C 3 478 ARG 478 771 771 ARG ARG A . n 
C 3 479 LEU 479 772 772 LEU LEU A . n 
C 3 480 GLU 480 773 773 GLU GLU A . n 
C 3 481 GLU 481 774 774 GLU GLU A . n 
C 3 482 MET 482 775 775 MET MET A . n 
C 3 483 GLY 483 776 776 GLY GLY A . n 
C 3 484 ALA 484 777 777 ALA ALA A . n 
C 3 485 ARG 485 778 778 ARG ARG A . n 
C 3 486 MET 486 779 779 MET MET A . n 
C 3 487 LEU 487 780 780 LEU LEU A . n 
C 3 488 LEU 488 781 781 LEU LEU A . n 
C 3 489 GLN 489 782 782 GLN GLN A . n 
C 3 490 VAL 490 783 783 VAL VAL A . n 
C 3 491 HIS 491 784 784 HIS HIS A . n 
C 3 492 ASP 492 785 785 ASP ASP A . n 
C 3 493 GLU 493 786 786 GLU GLU A . n 
C 3 494 LEU 494 787 787 LEU LEU A . n 
C 3 495 VAL 495 788 788 VAL VAL A . n 
C 3 496 LEU 496 789 789 LEU LEU A . n 
C 3 497 GLU 497 790 790 GLU GLU A . n 
C 3 498 ALA 498 791 791 ALA ALA A . n 
C 3 499 PRO 499 792 792 PRO PRO A . n 
C 3 500 LYS 500 793 793 LYS LYS A . n 
C 3 501 GLU 501 794 794 GLU GLU A . n 
C 3 502 ARG 502 795 795 ARG ARG A . n 
C 3 503 ALA 503 796 796 ALA ALA A . n 
C 3 504 GLU 504 797 797 GLU GLU A . n 
C 3 505 ALA 505 798 798 ALA ALA A . n 
C 3 506 VAL 506 799 799 VAL VAL A . n 
C 3 507 ALA 507 800 800 ALA ALA A . n 
C 3 508 ARG 508 801 801 ARG ARG A . n 
C 3 509 LEU 509 802 802 LEU LEU A . n 
C 3 510 ALA 510 803 803 ALA ALA A . n 
C 3 511 LYS 511 804 804 LYS LYS A . n 
C 3 512 GLU 512 805 805 GLU GLU A . n 
C 3 513 VAL 513 806 806 VAL VAL A . n 
C 3 514 MET 514 807 807 MET MET A . n 
C 3 515 GLU 515 808 808 GLU GLU A . n 
C 3 516 GLY 516 809 809 GLY GLY A . n 
C 3 517 VAL 517 810 810 VAL VAL A . n 
C 3 518 TYR 518 811 811 TYR TYR A . n 
C 3 519 PRO 519 812 812 PRO PRO A . n 
C 3 520 LEU 520 813 813 LEU LEU A . n 
C 3 521 ALA 521 814 814 ALA ALA A . n 
C 3 522 VAL 522 815 815 VAL VAL A . n 
C 3 523 PRO 523 816 816 PRO PRO A . n 
C 3 524 LEU 524 817 817 LEU LEU A . n 
C 3 525 GLU 525 818 818 GLU GLU A . n 
C 3 526 VAL 526 819 819 VAL VAL A . n 
C 3 527 GLU 527 820 820 GLU GLU A . n 
C 3 528 VAL 528 821 821 VAL VAL A . n 
C 3 529 GLY 529 822 822 GLY GLY A . n 
C 3 530 ILE 530 823 823 ILE ILE A . n 
C 3 531 GLY 531 824 824 GLY GLY A . n 
C 3 532 GLU 532 825 825 GLU GLU A . n 
C 3 533 ASP 533 826 826 ASP ASP A . n 
C 3 534 TRP 534 827 827 TRP TRP A . n 
C 3 535 LEU 535 828 828 LEU LEU A . n 
C 3 536 SER 536 829 829 SER SER A . n 
C 3 537 ALA 537 830 830 ALA ALA A . n 
C 3 538 LYS 538 831 831 LYS LYS A . n 
C 3 539 GLU 539 832 832 GLU GLU A . n 
D 1 1   DG  1   101 101 DG  DG  E . n 
D 1 2   DA  2   102 102 DA  DA  E . n 
D 1 3   DC  3   103 103 DC  DC  E . n 
D 1 4   DC  4   104 104 DC  DC  E . n 
D 1 5   DA  5   105 105 DA  DA  E . n 
D 1 6   DC  6   106 106 DC  DC  E . n 
D 1 7   DG  7   107 107 DG  DG  E . n 
D 1 8   DG  8   108 108 DG  DG  E . n 
D 1 9   DC  9   109 109 DC  DC  E . n 
D 1 10  DG  10  110 110 DG  DG  E . n 
D 1 11  DC  11  111 111 DC  DC  E . n 
D 1 12  DOC 12  112 112 DOC DOC E . n 
E 2 1   DA  1   202 202 DA  DA  F . n 
E 2 2   DA  2   203 203 DA  DA  F . n 
E 2 3   DC  3   204 204 DC  DC  F . n 
E 2 4   DG  4   205 205 DG  DG  F . n 
E 2 5   DG  5   206 206 DG  DG  F . n 
E 2 6   DC  6   207 207 DC  DC  F . n 
E 2 7   DG  7   208 208 DG  DG  F . n 
E 2 8   DC  8   209 209 DC  DC  F . n 
E 2 9   DC  9   210 210 DC  DC  F . n 
E 2 10  DG  10  211 211 DG  DG  F . n 
E 2 11  DT  11  212 212 DT  DT  F . n 
E 2 12  DG  12  213 213 DG  DG  F . n 
E 2 13  DG  13  214 214 DG  DG  F . n 
E 2 14  DT  14  215 215 DT  DT  F . n 
E 2 15  DC  15  216 216 DC  DC  F . n 
E 2 16  OMG 16  217 217 OMG OMG F . n 
F 3 1   MET 1   294 ?   ?   ?   D . n 
F 3 2   GLU 2   295 295 GLU GLU D . n 
F 3 3   GLU 3   296 296 GLU GLU D . n 
F 3 4   ALA 4   297 297 ALA ALA D . n 
F 3 5   PRO 5   298 298 PRO PRO D . n 
F 3 6   TRP 6   299 299 TRP TRP D . n 
F 3 7   PRO 7   300 300 PRO PRO D . n 
F 3 8   PRO 8   301 301 PRO PRO D . n 
F 3 9   PRO 9   302 302 PRO PRO D . n 
F 3 10  GLU 10  303 303 GLU GLU D . n 
F 3 11  GLY 11  304 304 GLY GLY D . n 
F 3 12  ALA 12  305 305 ALA ALA D . n 
F 3 13  PHE 13  306 306 PHE PHE D . n 
F 3 14  VAL 14  307 307 VAL VAL D . n 
F 3 15  GLY 15  308 308 GLY GLY D . n 
F 3 16  PHE 16  309 309 PHE PHE D . n 
F 3 17  VAL 17  310 310 VAL VAL D . n 
F 3 18  LEU 18  311 311 LEU LEU D . n 
F 3 19  SER 19  312 312 SER SER D . n 
F 3 20  ARG 20  313 313 ARG ARG D . n 
F 3 21  LYS 21  314 314 LYS LYS D . n 
F 3 22  GLU 22  315 315 GLU GLU D . n 
F 3 23  PRO 23  316 316 PRO PRO D . n 
F 3 24  MET 24  317 317 MET MET D . n 
F 3 25  TRP 25  318 318 TRP TRP D . n 
F 3 26  ALA 26  319 319 ALA ALA D . n 
F 3 27  ASP 27  320 320 ASP ASP D . n 
F 3 28  LEU 28  321 321 LEU LEU D . n 
F 3 29  LEU 29  322 322 LEU LEU D . n 
F 3 30  ALA 30  323 323 ALA ALA D . n 
F 3 31  LEU 31  324 324 LEU LEU D . n 
F 3 32  ALA 32  325 325 ALA ALA D . n 
F 3 33  ALA 33  326 326 ALA ALA D . n 
F 3 34  ALA 34  327 327 ALA ALA D . n 
F 3 35  ARG 35  328 328 ARG ARG D . n 
F 3 36  GLY 36  329 329 GLY GLY D . n 
F 3 37  GLY 37  330 330 GLY GLY D . n 
F 3 38  ARG 38  331 331 ARG ARG D . n 
F 3 39  VAL 39  332 332 VAL VAL D . n 
F 3 40  HIS 40  333 333 HIS HIS D . n 
F 3 41  ARG 41  334 334 ARG ARG D . n 
F 3 42  ALA 42  335 335 ALA ALA D . n 
F 3 43  PRO 43  336 336 PRO PRO D . n 
F 3 44  GLU 44  337 337 GLU GLU D . n 
F 3 45  PRO 45  338 338 PRO PRO D . n 
F 3 46  TYR 46  339 339 TYR TYR D . n 
F 3 47  LYS 47  340 340 LYS LYS D . n 
F 3 48  ALA 48  341 341 ALA ALA D . n 
F 3 49  LEU 49  342 342 LEU LEU D . n 
F 3 50  ARG 50  343 343 ARG ARG D . n 
F 3 51  ASP 51  344 344 ASP ASP D . n 
F 3 52  LEU 52  345 345 LEU LEU D . n 
F 3 53  LYS 53  346 346 LYS LYS D . n 
F 3 54  GLU 54  347 347 GLU GLU D . n 
F 3 55  ALA 55  348 348 ALA ALA D . n 
F 3 56  ARG 56  349 349 ARG ARG D . n 
F 3 57  GLY 57  350 350 GLY GLY D . n 
F 3 58  LEU 58  351 351 LEU LEU D . n 
F 3 59  LEU 59  352 352 LEU LEU D . n 
F 3 60  ALA 60  353 353 ALA ALA D . n 
F 3 61  LYS 61  354 354 LYS LYS D . n 
F 3 62  ASP 62  355 355 ASP ASP D . n 
F 3 63  LEU 63  356 356 LEU LEU D . n 
F 3 64  SER 64  357 357 SER SER D . n 
F 3 65  VAL 65  358 358 VAL VAL D . n 
F 3 66  LEU 66  359 359 LEU LEU D . n 
F 3 67  ALA 67  360 360 ALA ALA D . n 
F 3 68  LEU 68  361 361 LEU LEU D . n 
F 3 69  ARG 69  362 362 ARG ARG D . n 
F 3 70  GLU 70  363 363 GLU GLU D . n 
F 3 71  GLY 71  364 364 GLY GLY D . n 
F 3 72  LEU 72  365 365 LEU LEU D . n 
F 3 73  GLY 73  366 366 GLY GLY D . n 
F 3 74  LEU 74  367 367 LEU LEU D . n 
F 3 75  PRO 75  368 368 PRO PRO D . n 
F 3 76  PRO 76  369 369 PRO PRO D . n 
F 3 77  GLY 77  370 370 GLY GLY D . n 
F 3 78  ASP 78  371 371 ASP ASP D . n 
F 3 79  ASP 79  372 372 ASP ASP D . n 
F 3 80  PRO 80  373 373 PRO PRO D . n 
F 3 81  MET 81  374 374 MET MET D . n 
F 3 82  LEU 82  375 375 LEU LEU D . n 
F 3 83  LEU 83  376 376 LEU LEU D . n 
F 3 84  ALA 84  377 377 ALA ALA D . n 
F 3 85  TYR 85  378 378 TYR TYR D . n 
F 3 86  LEU 86  379 379 LEU LEU D . n 
F 3 87  LEU 87  380 380 LEU LEU D . n 
F 3 88  ASP 88  381 381 ASP ASP D . n 
F 3 89  PRO 89  382 382 PRO PRO D . n 
F 3 90  SER 90  383 383 SER SER D . n 
F 3 91  ASN 91  384 384 ASN ASN D . n 
F 3 92  THR 92  385 385 THR THR D . n 
F 3 93  THR 93  386 386 THR THR D . n 
F 3 94  PRO 94  387 387 PRO PRO D . n 
F 3 95  GLU 95  388 388 GLU GLU D . n 
F 3 96  GLY 96  389 389 GLY GLY D . n 
F 3 97  VAL 97  390 390 VAL VAL D . n 
F 3 98  ALA 98  391 391 ALA ALA D . n 
F 3 99  ARG 99  392 392 ARG ARG D . n 
F 3 100 ARG 100 393 393 ARG ARG D . n 
F 3 101 TYR 101 394 394 TYR TYR D . n 
F 3 102 GLY 102 395 395 GLY GLY D . n 
F 3 103 GLY 103 396 396 GLY GLY D . n 
F 3 104 GLU 104 397 397 GLU GLU D . n 
F 3 105 TRP 105 398 398 TRP TRP D . n 
F 3 106 THR 106 399 399 THR THR D . n 
F 3 107 GLU 107 400 400 GLU GLU D . n 
F 3 108 GLU 108 401 401 GLU GLU D . n 
F 3 109 ALA 109 402 402 ALA ALA D . n 
F 3 110 GLY 110 403 403 GLY GLY D . n 
F 3 111 GLU 111 404 404 GLU GLU D . n 
F 3 112 ARG 112 405 405 ARG ARG D . n 
F 3 113 ALA 113 406 406 ALA ALA D . n 
F 3 114 ALA 114 407 407 ALA ALA D . n 
F 3 115 LEU 115 408 408 LEU LEU D . n 
F 3 116 SER 116 409 409 SER SER D . n 
F 3 117 GLU 117 410 410 GLU GLU D . n 
F 3 118 ARG 118 411 411 ARG ARG D . n 
F 3 119 LEU 119 412 412 LEU LEU D . n 
F 3 120 PHE 120 413 413 PHE PHE D . n 
F 3 121 ALA 121 414 414 ALA ALA D . n 
F 3 122 ASN 122 415 415 ASN ASN D . n 
F 3 123 LEU 123 416 416 LEU LEU D . n 
F 3 124 TRP 124 417 417 TRP TRP D . n 
F 3 125 GLY 125 418 418 GLY GLY D . n 
F 3 126 ARG 126 419 419 ARG ARG D . n 
F 3 127 LEU 127 420 420 LEU LEU D . n 
F 3 128 GLU 128 421 421 GLU GLU D . n 
F 3 129 GLY 129 422 422 GLY GLY D . n 
F 3 130 GLU 130 423 423 GLU GLU D . n 
F 3 131 GLU 131 424 424 GLU GLU D . n 
F 3 132 ARG 132 425 425 ARG ARG D . n 
F 3 133 LEU 133 426 426 LEU LEU D . n 
F 3 134 LEU 134 427 427 LEU LEU D . n 
F 3 135 TRP 135 428 428 TRP TRP D . n 
F 3 136 LEU 136 429 429 LEU LEU D . n 
F 3 137 TYR 137 430 430 TYR TYR D . n 
F 3 138 ARG 138 431 431 ARG ARG D . n 
F 3 139 GLU 139 432 432 GLU GLU D . n 
F 3 140 VAL 140 433 433 VAL VAL D . n 
F 3 141 GLU 141 434 434 GLU GLU D . n 
F 3 142 ARG 142 435 435 ARG ARG D . n 
F 3 143 PRO 143 436 436 PRO PRO D . n 
F 3 144 LEU 144 437 437 LEU LEU D . n 
F 3 145 SER 145 438 438 SER SER D . n 
F 3 146 ALA 146 439 439 ALA ALA D . n 
F 3 147 VAL 147 440 440 VAL VAL D . n 
F 3 148 LEU 148 441 441 LEU LEU D . n 
F 3 149 ALA 149 442 442 ALA ALA D . n 
F 3 150 HIS 150 443 443 HIS HIS D . n 
F 3 151 MET 151 444 444 MET MET D . n 
F 3 152 GLU 152 445 445 GLU GLU D . n 
F 3 153 ALA 153 446 446 ALA ALA D . n 
F 3 154 THR 154 447 447 THR THR D . n 
F 3 155 GLY 155 448 448 GLY GLY D . n 
F 3 156 VAL 156 449 449 VAL VAL D . n 
F 3 157 ARG 157 450 450 ARG ARG D . n 
F 3 158 LEU 158 451 451 LEU LEU D . n 
F 3 159 ASP 159 452 452 ASP ASP D . n 
F 3 160 VAL 160 453 453 VAL VAL D . n 
F 3 161 ALA 161 454 454 ALA ALA D . n 
F 3 162 TYR 162 455 455 TYR TYR D . n 
F 3 163 LEU 163 456 456 LEU LEU D . n 
F 3 164 ARG 164 457 457 ARG ARG D . n 
F 3 165 ALA 165 458 458 ALA ALA D . n 
F 3 166 LEU 166 459 459 LEU LEU D . n 
F 3 167 SER 167 460 460 SER SER D . n 
F 3 168 LEU 168 461 461 LEU LEU D . n 
F 3 169 GLU 169 462 462 GLU GLU D . n 
F 3 170 VAL 170 463 463 VAL VAL D . n 
F 3 171 ALA 171 464 464 ALA ALA D . n 
F 3 172 GLU 172 465 465 GLU GLU D . n 
F 3 173 GLU 173 466 466 GLU GLU D . n 
F 3 174 ILE 174 467 467 ILE ILE D . n 
F 3 175 ALA 175 468 468 ALA ALA D . n 
F 3 176 ARG 176 469 469 ARG ARG D . n 
F 3 177 LEU 177 470 470 LEU LEU D . n 
F 3 178 GLU 178 471 471 GLU GLU D . n 
F 3 179 ALA 179 472 472 ALA ALA D . n 
F 3 180 GLU 180 473 473 GLU GLU D . n 
F 3 181 VAL 181 474 474 VAL VAL D . n 
F 3 182 PHE 182 475 475 PHE PHE D . n 
F 3 183 ARG 183 476 476 ARG ARG D . n 
F 3 184 LEU 184 477 477 LEU LEU D . n 
F 3 185 ALA 185 478 478 ALA ALA D . n 
F 3 186 GLY 186 479 479 GLY GLY D . n 
F 3 187 HIS 187 480 480 HIS HIS D . n 
F 3 188 PRO 188 481 481 PRO PRO D . n 
F 3 189 PHE 189 482 482 PHE PHE D . n 
F 3 190 ASN 190 483 483 ASN ASN D . n 
F 3 191 LEU 191 484 484 LEU LEU D . n 
F 3 192 ASN 192 485 485 ASN ASN D . n 
F 3 193 SER 193 486 486 SER SER D . n 
F 3 194 ARG 194 487 487 ARG ARG D . n 
F 3 195 ASP 195 488 488 ASP ASP D . n 
F 3 196 GLN 196 489 489 GLN GLN D . n 
F 3 197 LEU 197 490 490 LEU LEU D . n 
F 3 198 GLU 198 491 491 GLU GLU D . n 
F 3 199 ARG 199 492 492 ARG ARG D . n 
F 3 200 VAL 200 493 493 VAL VAL D . n 
F 3 201 LEU 201 494 494 LEU LEU D . n 
F 3 202 PHE 202 495 495 PHE PHE D . n 
F 3 203 ASP 203 496 496 ASP ASP D . n 
F 3 204 GLU 204 497 497 GLU GLU D . n 
F 3 205 LEU 205 498 498 LEU LEU D . n 
F 3 206 GLY 206 499 499 GLY GLY D . n 
F 3 207 LEU 207 500 500 LEU LEU D . n 
F 3 208 PRO 208 501 501 PRO PRO D . n 
F 3 209 ALA 209 502 502 ALA ALA D . n 
F 3 210 ILE 210 503 503 ILE ILE D . n 
F 3 211 GLY 211 504 504 GLY GLY D . n 
F 3 212 LYS 212 505 505 LYS LYS D . n 
F 3 213 THR 213 506 506 THR THR D . n 
F 3 214 GLU 214 507 507 GLU GLU D . n 
F 3 215 LYS 215 508 508 LYS LYS D . n 
F 3 216 THR 216 509 509 THR THR D . n 
F 3 217 GLY 217 510 510 GLY GLY D . n 
F 3 218 LYS 218 511 511 LYS LYS D . n 
F 3 219 ARG 219 512 512 ARG ARG D . n 
F 3 220 SER 220 513 513 SER SER D . n 
F 3 221 THR 221 514 514 THR THR D . n 
F 3 222 SER 222 515 515 SER SER D . n 
F 3 223 ALA 223 516 516 ALA ALA D . n 
F 3 224 ALA 224 517 517 ALA ALA D . n 
F 3 225 ALA 225 518 518 ALA ALA D . n 
F 3 226 LEU 226 519 519 LEU LEU D . n 
F 3 227 GLU 227 520 520 GLU GLU D . n 
F 3 228 ALA 228 521 521 ALA ALA D . n 
F 3 229 LEU 229 522 522 LEU LEU D . n 
F 3 230 ARG 230 523 523 ARG ARG D . n 
F 3 231 GLU 231 524 524 GLU GLU D . n 
F 3 232 ALA 232 525 525 ALA ALA D . n 
F 3 233 HIS 233 526 526 HIS HIS D . n 
F 3 234 PRO 234 527 527 PRO PRO D . n 
F 3 235 ILE 235 528 528 ILE ILE D . n 
F 3 236 VAL 236 529 529 VAL VAL D . n 
F 3 237 GLU 237 530 530 GLU GLU D . n 
F 3 238 LYS 238 531 531 LYS LYS D . n 
F 3 239 ILE 239 532 532 ILE ILE D . n 
F 3 240 LEU 240 533 533 LEU LEU D . n 
F 3 241 GLN 241 534 534 GLN GLN D . n 
F 3 242 TYR 242 535 535 TYR TYR D . n 
F 3 243 ARG 243 536 536 ARG ARG D . n 
F 3 244 GLU 244 537 537 GLU GLU D . n 
F 3 245 LEU 245 538 538 LEU LEU D . n 
F 3 246 THR 246 539 539 THR THR D . n 
F 3 247 LYS 247 540 540 LYS LYS D . n 
F 3 248 LEU 248 541 541 LEU LEU D . n 
F 3 249 LYS 249 542 542 LYS LYS D . n 
F 3 250 SER 250 543 543 SER SER D . n 
F 3 251 THR 251 544 544 THR THR D . n 
F 3 252 TYR 252 545 545 TYR TYR D . n 
F 3 253 ILE 253 546 546 ILE ILE D . n 
F 3 254 ASP 254 547 547 ASP ASP D . n 
F 3 255 PRO 255 548 548 PRO PRO D . n 
F 3 256 LEU 256 549 549 LEU LEU D . n 
F 3 257 PRO 257 550 550 PRO PRO D . n 
F 3 258 ASP 258 551 551 ASP ASP D . n 
F 3 259 LEU 259 552 552 LEU LEU D . n 
F 3 260 ILE 260 553 553 ILE ILE D . n 
F 3 261 HIS 261 554 554 HIS HIS D . n 
F 3 262 PRO 262 555 555 PRO PRO D . n 
F 3 263 ARG 263 556 556 ARG ARG D . n 
F 3 264 THR 264 557 557 THR THR D . n 
F 3 265 GLY 265 558 558 GLY GLY D . n 
F 3 266 ARG 266 559 559 ARG ARG D . n 
F 3 267 LEU 267 560 560 LEU LEU D . n 
F 3 268 HIS 268 561 561 HIS HIS D . n 
F 3 269 THR 269 562 562 THR THR D . n 
F 3 270 ARG 270 563 563 ARG ARG D . n 
F 3 271 PHE 271 564 564 PHE PHE D . n 
F 3 272 ASN 272 565 565 ASN ASN D . n 
F 3 273 GLN 273 566 566 GLN GLN D . n 
F 3 274 THR 274 567 567 THR THR D . n 
F 3 275 ALA 275 568 568 ALA ALA D . n 
F 3 276 THR 276 569 569 THR THR D . n 
F 3 277 ALA 277 570 570 ALA ALA D . n 
F 3 278 THR 278 571 571 THR THR D . n 
F 3 279 GLY 279 572 572 GLY GLY D . n 
F 3 280 ARG 280 573 573 ARG ARG D . n 
F 3 281 LEU 281 574 574 LEU LEU D . n 
F 3 282 SER 282 575 575 SER SER D . n 
F 3 283 SER 283 576 576 SER SER D . n 
F 3 284 SER 284 577 577 SER SER D . n 
F 3 285 ASP 285 578 578 ASP ASP D . n 
F 3 286 PRO 286 579 579 PRO PRO D . n 
F 3 287 ASN 287 580 580 ASN ASN D . n 
F 3 288 LEU 288 581 581 LEU LEU D . n 
F 3 289 GLN 289 582 582 GLN GLN D . n 
F 3 290 SER 290 583 583 SER SER D . n 
F 3 291 ILE 291 584 584 ILE ILE D . n 
F 3 292 PRO 292 585 585 PRO PRO D . n 
F 3 293 VAL 293 586 586 VAL VAL D . n 
F 3 294 ARG 294 587 587 ARG ARG D . n 
F 3 295 THR 295 588 588 THR THR D . n 
F 3 296 PRO 296 589 589 PRO PRO D . n 
F 3 297 LEU 297 590 590 LEU LEU D . n 
F 3 298 GLY 298 591 591 GLY GLY D . n 
F 3 299 GLN 299 592 592 GLN GLN D . n 
F 3 300 ARG 300 593 593 ARG ARG D . n 
F 3 301 ILE 301 594 594 ILE ILE D . n 
F 3 302 ARG 302 595 595 ARG ARG D . n 
F 3 303 ARG 303 596 596 ARG ARG D . n 
F 3 304 ALA 304 597 597 ALA ALA D . n 
F 3 305 PHE 305 598 598 PHE PHE D . n 
F 3 306 ILE 306 599 599 ILE ILE D . n 
F 3 307 ALA 307 600 600 ALA ALA D . n 
F 3 308 GLU 308 601 601 GLU GLU D . n 
F 3 309 GLU 309 602 602 GLU GLU D . n 
F 3 310 GLY 310 603 603 GLY GLY D . n 
F 3 311 TRP 311 604 604 TRP TRP D . n 
F 3 312 LEU 312 605 605 LEU LEU D . n 
F 3 313 LEU 313 606 606 LEU LEU D . n 
F 3 314 VAL 314 607 607 VAL VAL D . n 
F 3 315 ALA 315 608 608 ALA ALA D . n 
F 3 316 LEU 316 609 609 LEU LEU D . n 
F 3 317 ASP 317 610 610 ASP ASP D . n 
F 3 318 TYR 318 611 611 TYR TYR D . n 
F 3 319 SER 319 612 612 SER SER D . n 
F 3 320 GLN 320 613 613 GLN GLN D . n 
F 3 321 GLU 321 614 614 GLU GLU D . n 
F 3 322 GLY 322 615 615 GLY GLY D . n 
F 3 323 LEU 323 616 616 LEU LEU D . n 
F 3 324 ARG 324 617 617 ARG ARG D . n 
F 3 325 VAL 325 618 618 VAL VAL D . n 
F 3 326 LEU 326 619 619 LEU LEU D . n 
F 3 327 ALA 327 620 620 ALA ALA D . n 
F 3 328 HIS 328 621 621 HIS HIS D . n 
F 3 329 LEU 329 622 622 LEU LEU D . n 
F 3 330 SER 330 623 623 SER SER D . n 
F 3 331 GLY 331 624 624 GLY GLY D . n 
F 3 332 ASP 332 625 625 ASP ASP D . n 
F 3 333 GLU 333 626 626 GLU GLU D . n 
F 3 334 ASN 334 627 627 ASN ASN D . n 
F 3 335 LEU 335 628 628 LEU LEU D . n 
F 3 336 ILE 336 629 629 ILE ILE D . n 
F 3 337 ARG 337 630 630 ARG ARG D . n 
F 3 338 VAL 338 631 631 VAL VAL D . n 
F 3 339 PHE 339 632 632 PHE PHE D . n 
F 3 340 GLN 340 633 633 GLN GLN D . n 
F 3 341 GLU 341 634 634 GLU GLU D . n 
F 3 342 GLY 342 635 635 GLY GLY D . n 
F 3 343 ARG 343 636 636 ARG ARG D . n 
F 3 344 ASP 344 637 637 ASP ASP D . n 
F 3 345 ILE 345 638 638 ILE ILE D . n 
F 3 346 HIS 346 639 639 HIS HIS D . n 
F 3 347 THR 347 640 640 THR THR D . n 
F 3 348 GLU 348 641 641 GLU GLU D . n 
F 3 349 THR 349 642 642 THR THR D . n 
F 3 350 ALA 350 643 643 ALA ALA D . n 
F 3 351 SER 351 644 644 SER SER D . n 
F 3 352 TRP 352 645 645 TRP TRP D . n 
F 3 353 MET 353 646 646 MET MET D . n 
F 3 354 PHE 354 647 647 PHE PHE D . n 
F 3 355 GLY 355 648 648 GLY GLY D . n 
F 3 356 VAL 356 649 649 VAL VAL D . n 
F 3 357 PRO 357 650 650 PRO PRO D . n 
F 3 358 ARG 358 651 651 ARG ARG D . n 
F 3 359 GLU 359 652 652 GLU GLU D . n 
F 3 360 ALA 360 653 653 ALA ALA D . n 
F 3 361 VAL 361 654 654 VAL VAL D . n 
F 3 362 ASN 362 655 655 ASN ASN D . n 
F 3 363 PRO 363 656 656 PRO PRO D . n 
F 3 364 LEU 364 657 657 LEU LEU D . n 
F 3 365 MET 365 658 658 MET MET D . n 
F 3 366 ARG 366 659 659 ARG ARG D . n 
F 3 367 ARG 367 660 660 ARG ARG D . n 
F 3 368 ALA 368 661 661 ALA ALA D . n 
F 3 369 ALA 369 662 662 ALA ALA D . n 
F 3 370 LYS 370 663 663 LYS LYS D . n 
F 3 371 THR 371 664 664 THR THR D . n 
F 3 372 ILE 372 665 665 ILE ILE D . n 
F 3 373 ASN 373 666 666 ASN ASN D . n 
F 3 374 PHE 374 667 667 PHE PHE D . n 
F 3 375 GLY 375 668 668 GLY GLY D . n 
F 3 376 VAL 376 669 669 VAL VAL D . n 
F 3 377 LEU 377 670 670 LEU LEU D . n 
F 3 378 TYR 378 671 671 TYR TYR D . n 
F 3 379 GLY 379 672 672 GLY GLY D . n 
F 3 380 MET 380 673 673 MET MET D . n 
F 3 381 SER 381 674 674 SER SER D . n 
F 3 382 ALA 382 675 675 ALA ALA D . n 
F 3 383 HIS 383 676 676 HIS HIS D . n 
F 3 384 ARG 384 677 677 ARG ARG D . n 
F 3 385 LEU 385 678 678 LEU LEU D . n 
F 3 386 SER 386 679 679 SER SER D . n 
F 3 387 GLN 387 680 680 GLN GLN D . n 
F 3 388 LYS 388 681 681 LYS LYS D . n 
F 3 389 LEU 389 682 682 LEU LEU D . n 
F 3 390 ALA 390 683 683 ALA ALA D . n 
F 3 391 ILE 391 684 684 ILE ILE D . n 
F 3 392 PRO 392 685 685 PRO PRO D . n 
F 3 393 TYR 393 686 686 TYR TYR D . n 
F 3 394 GLU 394 687 687 GLU GLU D . n 
F 3 395 GLU 395 688 688 GLU GLU D . n 
F 3 396 ALA 396 689 689 ALA ALA D . n 
F 3 397 GLN 397 690 690 GLN GLN D . n 
F 3 398 ALA 398 691 691 ALA ALA D . n 
F 3 399 PHE 399 692 692 PHE PHE D . n 
F 3 400 ILE 400 693 693 ILE ILE D . n 
F 3 401 GLU 401 694 694 GLU GLU D . n 
F 3 402 ARG 402 695 695 ARG ARG D . n 
F 3 403 TYR 403 696 696 TYR TYR D . n 
F 3 404 PHE 404 697 697 PHE PHE D . n 
F 3 405 GLN 405 698 698 GLN GLN D . n 
F 3 406 SER 406 699 699 SER SER D . n 
F 3 407 PHE 407 700 700 PHE PHE D . n 
F 3 408 PRO 408 701 701 PRO PRO D . n 
F 3 409 LYS 409 702 702 LYS LYS D . n 
F 3 410 VAL 410 703 703 VAL VAL D . n 
F 3 411 ARG 411 704 704 ARG ARG D . n 
F 3 412 ALA 412 705 705 ALA ALA D . n 
F 3 413 TRP 413 706 706 TRP TRP D . n 
F 3 414 ILE 414 707 707 ILE ILE D . n 
F 3 415 GLU 415 708 708 GLU GLU D . n 
F 3 416 LYS 416 709 709 LYS LYS D . n 
F 3 417 THR 417 710 710 THR THR D . n 
F 3 418 LEU 418 711 711 LEU LEU D . n 
F 3 419 GLU 419 712 712 GLU GLU D . n 
F 3 420 GLU 420 713 713 GLU GLU D . n 
F 3 421 GLY 421 714 714 GLY GLY D . n 
F 3 422 ARG 422 715 715 ARG ARG D . n 
F 3 423 ARG 423 716 716 ARG ARG D . n 
F 3 424 ARG 424 717 717 ARG ARG D . n 
F 3 425 GLY 425 718 718 GLY GLY D . n 
F 3 426 TYR 426 719 719 TYR TYR D . n 
F 3 427 VAL 427 720 720 VAL VAL D . n 
F 3 428 GLU 428 721 721 GLU GLU D . n 
F 3 429 THR 429 722 722 THR THR D . n 
F 3 430 LEU 430 723 723 LEU LEU D . n 
F 3 431 PHE 431 724 724 PHE PHE D . n 
F 3 432 GLY 432 725 725 GLY GLY D . n 
F 3 433 ARG 433 726 726 ARG ARG D . n 
F 3 434 ARG 434 727 727 ARG ARG D . n 
F 3 435 ARG 435 728 728 ARG ARG D . n 
F 3 436 TYR 436 729 729 TYR TYR D . n 
F 3 437 VAL 437 730 730 VAL VAL D . n 
F 3 438 PRO 438 731 731 PRO PRO D . n 
F 3 439 ASP 439 732 732 ASP ASP D . n 
F 3 440 LEU 440 733 733 LEU LEU D . n 
F 3 441 GLU 441 734 734 GLU GLU D . n 
F 3 442 ALA 442 735 735 ALA ALA D . n 
F 3 443 ARG 443 736 736 ARG ARG D . n 
F 3 444 VAL 444 737 737 VAL VAL D . n 
F 3 445 LYS 445 738 738 LYS LYS D . n 
F 3 446 SER 446 739 739 SER SER D . n 
F 3 447 VAL 447 740 740 VAL VAL D . n 
F 3 448 ARG 448 741 741 ARG ARG D . n 
F 3 449 GLN 449 742 742 GLN GLN D . n 
F 3 450 ALA 450 743 743 ALA ALA D . n 
F 3 451 ALA 451 744 744 ALA ALA D . n 
F 3 452 GLU 452 745 745 GLU GLU D . n 
F 3 453 ARG 453 746 746 ARG ARG D . n 
F 3 454 ARG 454 747 747 ARG ARG D . n 
F 3 455 ALA 455 748 748 ALA ALA D . n 
F 3 456 PHE 456 749 749 PHE PHE D . n 
F 3 457 ASN 457 750 750 ASN ASN D . n 
F 3 458 MET 458 751 751 MET MET D . n 
F 3 459 PRO 459 752 752 PRO PRO D . n 
F 3 460 VAL 460 753 753 VAL VAL D . n 
F 3 461 GLN 461 754 754 GLN GLN D . n 
F 3 462 GLY 462 755 755 GLY GLY D . n 
F 3 463 THR 463 756 756 THR THR D . n 
F 3 464 ALA 464 757 757 ALA ALA D . n 
F 3 465 ALA 465 758 758 ALA ALA D . n 
F 3 466 ASP 466 759 759 ASP ASP D . n 
F 3 467 LEU 467 760 760 LEU LEU D . n 
F 3 468 MET 468 761 761 MET MET D . n 
F 3 469 LYS 469 762 762 LYS LYS D . n 
F 3 470 LEU 470 763 763 LEU LEU D . n 
F 3 471 ALA 471 764 764 ALA ALA D . n 
F 3 472 MET 472 765 765 MET MET D . n 
F 3 473 VAL 473 766 766 VAL VAL D . n 
F 3 474 LYS 474 767 767 LYS LYS D . n 
F 3 475 LEU 475 768 768 LEU LEU D . n 
F 3 476 PHE 476 769 769 PHE PHE D . n 
F 3 477 PRO 477 770 770 PRO PRO D . n 
F 3 478 ARG 478 771 771 ARG ARG D . n 
F 3 479 LEU 479 772 772 LEU LEU D . n 
F 3 480 GLU 480 773 773 GLU GLU D . n 
F 3 481 GLU 481 774 774 GLU GLU D . n 
F 3 482 MET 482 775 775 MET MET D . n 
F 3 483 GLY 483 776 776 GLY GLY D . n 
F 3 484 ALA 484 777 777 ALA ALA D . n 
F 3 485 ARG 485 778 778 ARG ARG D . n 
F 3 486 MET 486 779 779 MET MET D . n 
F 3 487 LEU 487 780 780 LEU LEU D . n 
F 3 488 LEU 488 781 781 LEU LEU D . n 
F 3 489 GLN 489 782 782 GLN GLN D . n 
F 3 490 VAL 490 783 783 VAL VAL D . n 
F 3 491 HIS 491 784 784 HIS HIS D . n 
F 3 492 ASP 492 785 785 ASP ASP D . n 
F 3 493 GLU 493 786 786 GLU GLU D . n 
F 3 494 LEU 494 787 787 LEU LEU D . n 
F 3 495 VAL 495 788 788 VAL VAL D . n 
F 3 496 LEU 496 789 789 LEU LEU D . n 
F 3 497 GLU 497 790 790 GLU GLU D . n 
F 3 498 ALA 498 791 791 ALA ALA D . n 
F 3 499 PRO 499 792 792 PRO PRO D . n 
F 3 500 LYS 500 793 793 LYS LYS D . n 
F 3 501 GLU 501 794 794 GLU GLU D . n 
F 3 502 ARG 502 795 795 ARG ARG D . n 
F 3 503 ALA 503 796 796 ALA ALA D . n 
F 3 504 GLU 504 797 797 GLU GLU D . n 
F 3 505 ALA 505 798 798 ALA ALA D . n 
F 3 506 VAL 506 799 799 VAL VAL D . n 
F 3 507 ALA 507 800 800 ALA ALA D . n 
F 3 508 ARG 508 801 801 ARG ARG D . n 
F 3 509 LEU 509 802 802 LEU LEU D . n 
F 3 510 ALA 510 803 803 ALA ALA D . n 
F 3 511 LYS 511 804 804 LYS LYS D . n 
F 3 512 GLU 512 805 805 GLU GLU D . n 
F 3 513 VAL 513 806 806 VAL VAL D . n 
F 3 514 MET 514 807 807 MET MET D . n 
F 3 515 GLU 515 808 808 GLU GLU D . n 
F 3 516 GLY 516 809 809 GLY GLY D . n 
F 3 517 VAL 517 810 810 VAL VAL D . n 
F 3 518 TYR 518 811 811 TYR TYR D . n 
F 3 519 PRO 519 812 812 PRO PRO D . n 
F 3 520 LEU 520 813 813 LEU LEU D . n 
F 3 521 ALA 521 814 814 ALA ALA D . n 
F 3 522 VAL 522 815 815 VAL VAL D . n 
F 3 523 PRO 523 816 816 PRO PRO D . n 
F 3 524 LEU 524 817 817 LEU LEU D . n 
F 3 525 GLU 525 818 818 GLU GLU D . n 
F 3 526 VAL 526 819 819 VAL VAL D . n 
F 3 527 GLU 527 820 820 GLU GLU D . n 
F 3 528 VAL 528 821 821 VAL VAL D . n 
F 3 529 GLY 529 822 822 GLY GLY D . n 
F 3 530 ILE 530 823 823 ILE ILE D . n 
F 3 531 GLY 531 824 824 GLY GLY D . n 
F 3 532 GLU 532 825 825 GLU GLU D . n 
F 3 533 ASP 533 826 826 ASP ASP D . n 
F 3 534 TRP 534 827 827 TRP TRP D . n 
F 3 535 LEU 535 828 828 LEU LEU D . n 
F 3 536 SER 536 829 829 SER SER D . n 
F 3 537 ALA 537 830 830 ALA ALA D . n 
F 3 538 LYS 538 831 831 LYS LYS D . n 
F 3 539 GLU 539 832 832 GLU GLU D . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 A1LWE ? ? A1LWE ? ? 'SUBJECT OF INVESTIGATION' ? 
2 OMG   ? ? OMG   ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 4 MG    1   201  1   MG    MG  B . 
H 4 MG    1   901  901 MG    MG  A . 
I 4 MG    1   902  902 MG    MG  A . 
J 5 A1LWE 1   903  903 A1LWE OME A . 
K 6 PEG   1   904  1   PEG   PEG A . 
L 7 PO4   1   905  2   PO4   PO4 A . 
M 4 MG    1   201  2   MG    MG  E . 
N 4 MG    1   901  901 MG    MG  D . 
O 4 MG    1   902  902 MG    MG  D . 
P 5 A1LWE 1   903  903 A1LWE OME D . 
Q 6 PEG   1   904  2   PEG   PEG D . 
R 7 PO4   1   905  1   PO4   PO4 D . 
S 8 HOH   1   301  29  HOH   HOH B . 
S 8 HOH   2   302  333 HOH   HOH B . 
S 8 HOH   3   303  339 HOH   HOH B . 
S 8 HOH   4   304  56  HOH   HOH B . 
S 8 HOH   5   305  444 HOH   HOH B . 
S 8 HOH   6   306  407 HOH   HOH B . 
S 8 HOH   7   307  196 HOH   HOH B . 
S 8 HOH   8   308  140 HOH   HOH B . 
S 8 HOH   9   309  92  HOH   HOH B . 
S 8 HOH   10  310  605 HOH   HOH B . 
S 8 HOH   11  311  431 HOH   HOH B . 
S 8 HOH   12  312  606 HOH   HOH B . 
S 8 HOH   13  313  11  HOH   HOH B . 
S 8 HOH   14  314  417 HOH   HOH B . 
S 8 HOH   15  315  307 HOH   HOH B . 
S 8 HOH   16  316  576 HOH   HOH B . 
S 8 HOH   17  317  55  HOH   HOH B . 
S 8 HOH   18  318  154 HOH   HOH B . 
S 8 HOH   19  319  569 HOH   HOH B . 
S 8 HOH   20  320  533 HOH   HOH B . 
S 8 HOH   21  321  403 HOH   HOH B . 
S 8 HOH   22  322  367 HOH   HOH B . 
T 8 HOH   1   301  331 HOH   HOH C . 
T 8 HOH   2   302  302 HOH   HOH C . 
T 8 HOH   3   303  359 HOH   HOH C . 
T 8 HOH   4   304  497 HOH   HOH C . 
T 8 HOH   5   305  226 HOH   HOH C . 
T 8 HOH   6   306  491 HOH   HOH C . 
T 8 HOH   7   307  86  HOH   HOH C . 
T 8 HOH   8   308  143 HOH   HOH C . 
T 8 HOH   9   309  436 HOH   HOH C . 
T 8 HOH   10  310  203 HOH   HOH C . 
T 8 HOH   11  311  214 HOH   HOH C . 
T 8 HOH   12  312  514 HOH   HOH C . 
T 8 HOH   13  313  16  HOH   HOH C . 
T 8 HOH   14  314  221 HOH   HOH C . 
T 8 HOH   15  315  516 HOH   HOH C . 
T 8 HOH   16  316  469 HOH   HOH C . 
T 8 HOH   17  317  264 HOH   HOH C . 
T 8 HOH   18  318  83  HOH   HOH C . 
T 8 HOH   19  319  138 HOH   HOH C . 
T 8 HOH   20  320  512 HOH   HOH C . 
T 8 HOH   21  321  65  HOH   HOH C . 
T 8 HOH   22  322  539 HOH   HOH C . 
T 8 HOH   23  323  174 HOH   HOH C . 
T 8 HOH   24  324  114 HOH   HOH C . 
T 8 HOH   25  325  371 HOH   HOH C . 
T 8 HOH   26  326  553 HOH   HOH C . 
T 8 HOH   27  327  49  HOH   HOH C . 
T 8 HOH   28  328  369 HOH   HOH C . 
T 8 HOH   29  329  471 HOH   HOH C . 
T 8 HOH   30  330  273 HOH   HOH C . 
T 8 HOH   31  331  608 HOH   HOH C . 
T 8 HOH   32  332  607 HOH   HOH C . 
T 8 HOH   33  333  366 HOH   HOH C . 
U 8 HOH   1   1001 565 HOH   HOH A . 
U 8 HOH   2   1002 464 HOH   HOH A . 
U 8 HOH   3   1003 415 HOH   HOH A . 
U 8 HOH   4   1004 98  HOH   HOH A . 
U 8 HOH   5   1005 493 HOH   HOH A . 
U 8 HOH   6   1006 480 HOH   HOH A . 
U 8 HOH   7   1007 589 HOH   HOH A . 
U 8 HOH   8   1008 429 HOH   HOH A . 
U 8 HOH   9   1009 535 HOH   HOH A . 
U 8 HOH   10  1010 39  HOH   HOH A . 
U 8 HOH   11  1011 69  HOH   HOH A . 
U 8 HOH   12  1012 443 HOH   HOH A . 
U 8 HOH   13  1013 463 HOH   HOH A . 
U 8 HOH   14  1014 485 HOH   HOH A . 
U 8 HOH   15  1015 123 HOH   HOH A . 
U 8 HOH   16  1016 309 HOH   HOH A . 
U 8 HOH   17  1017 544 HOH   HOH A . 
U 8 HOH   18  1018 217 HOH   HOH A . 
U 8 HOH   19  1019 412 HOH   HOH A . 
U 8 HOH   20  1020 164 HOH   HOH A . 
U 8 HOH   21  1021 487 HOH   HOH A . 
U 8 HOH   22  1022 517 HOH   HOH A . 
U 8 HOH   23  1023 473 HOH   HOH A . 
U 8 HOH   24  1024 376 HOH   HOH A . 
U 8 HOH   25  1025 515 HOH   HOH A . 
U 8 HOH   26  1026 318 HOH   HOH A . 
U 8 HOH   27  1027 4   HOH   HOH A . 
U 8 HOH   28  1028 52  HOH   HOH A . 
U 8 HOH   29  1029 148 HOH   HOH A . 
U 8 HOH   30  1030 492 HOH   HOH A . 
U 8 HOH   31  1031 191 HOH   HOH A . 
U 8 HOH   32  1032 442 HOH   HOH A . 
U 8 HOH   33  1033 280 HOH   HOH A . 
U 8 HOH   34  1034 332 HOH   HOH A . 
U 8 HOH   35  1035 22  HOH   HOH A . 
U 8 HOH   36  1036 269 HOH   HOH A . 
U 8 HOH   37  1037 389 HOH   HOH A . 
U 8 HOH   38  1038 418 HOH   HOH A . 
U 8 HOH   39  1039 420 HOH   HOH A . 
U 8 HOH   40  1040 144 HOH   HOH A . 
U 8 HOH   41  1041 132 HOH   HOH A . 
U 8 HOH   42  1042 301 HOH   HOH A . 
U 8 HOH   43  1043 96  HOH   HOH A . 
U 8 HOH   44  1044 119 HOH   HOH A . 
U 8 HOH   45  1045 402 HOH   HOH A . 
U 8 HOH   46  1046 179 HOH   HOH A . 
U 8 HOH   47  1047 236 HOH   HOH A . 
U 8 HOH   48  1048 110 HOH   HOH A . 
U 8 HOH   49  1049 250 HOH   HOH A . 
U 8 HOH   50  1050 588 HOH   HOH A . 
U 8 HOH   51  1051 210 HOH   HOH A . 
U 8 HOH   52  1052 80  HOH   HOH A . 
U 8 HOH   53  1053 225 HOH   HOH A . 
U 8 HOH   54  1054 325 HOH   HOH A . 
U 8 HOH   55  1055 532 HOH   HOH A . 
U 8 HOH   56  1056 28  HOH   HOH A . 
U 8 HOH   57  1057 488 HOH   HOH A . 
U 8 HOH   58  1058 234 HOH   HOH A . 
U 8 HOH   59  1059 240 HOH   HOH A . 
U 8 HOH   60  1060 170 HOH   HOH A . 
U 8 HOH   61  1061 287 HOH   HOH A . 
U 8 HOH   62  1062 105 HOH   HOH A . 
U 8 HOH   63  1063 448 HOH   HOH A . 
U 8 HOH   64  1064 94  HOH   HOH A . 
U 8 HOH   65  1065 107 HOH   HOH A . 
U 8 HOH   66  1066 89  HOH   HOH A . 
U 8 HOH   67  1067 454 HOH   HOH A . 
U 8 HOH   68  1068 394 HOH   HOH A . 
U 8 HOH   69  1069 380 HOH   HOH A . 
U 8 HOH   70  1070 47  HOH   HOH A . 
U 8 HOH   71  1071 537 HOH   HOH A . 
U 8 HOH   72  1072 446 HOH   HOH A . 
U 8 HOH   73  1073 206 HOH   HOH A . 
U 8 HOH   74  1074 409 HOH   HOH A . 
U 8 HOH   75  1075 227 HOH   HOH A . 
U 8 HOH   76  1076 61  HOH   HOH A . 
U 8 HOH   77  1077 323 HOH   HOH A . 
U 8 HOH   78  1078 258 HOH   HOH A . 
U 8 HOH   79  1079 194 HOH   HOH A . 
U 8 HOH   80  1080 19  HOH   HOH A . 
U 8 HOH   81  1081 484 HOH   HOH A . 
U 8 HOH   82  1082 168 HOH   HOH A . 
U 8 HOH   83  1083 308 HOH   HOH A . 
U 8 HOH   84  1084 438 HOH   HOH A . 
U 8 HOH   85  1085 393 HOH   HOH A . 
U 8 HOH   86  1086 87  HOH   HOH A . 
U 8 HOH   87  1087 271 HOH   HOH A . 
U 8 HOH   88  1088 518 HOH   HOH A . 
U 8 HOH   89  1089 350 HOH   HOH A . 
U 8 HOH   90  1090 355 HOH   HOH A . 
U 8 HOH   91  1091 358 HOH   HOH A . 
U 8 HOH   92  1092 405 HOH   HOH A . 
U 8 HOH   93  1093 20  HOH   HOH A . 
U 8 HOH   94  1094 451 HOH   HOH A . 
U 8 HOH   95  1095 134 HOH   HOH A . 
U 8 HOH   96  1096 315 HOH   HOH A . 
U 8 HOH   97  1097 397 HOH   HOH A . 
U 8 HOH   98  1098 242 HOH   HOH A . 
U 8 HOH   99  1099 482 HOH   HOH A . 
U 8 HOH   100 1100 593 HOH   HOH A . 
U 8 HOH   101 1101 592 HOH   HOH A . 
U 8 HOH   102 1102 510 HOH   HOH A . 
U 8 HOH   103 1103 595 HOH   HOH A . 
U 8 HOH   104 1104 161 HOH   HOH A . 
U 8 HOH   105 1105 243 HOH   HOH A . 
U 8 HOH   106 1106 399 HOH   HOH A . 
U 8 HOH   107 1107 344 HOH   HOH A . 
U 8 HOH   108 1108 171 HOH   HOH A . 
U 8 HOH   109 1109 474 HOH   HOH A . 
U 8 HOH   110 1110 445 HOH   HOH A . 
U 8 HOH   111 1111 385 HOH   HOH A . 
U 8 HOH   112 1112 530 HOH   HOH A . 
U 8 HOH   113 1113 90  HOH   HOH A . 
U 8 HOH   114 1114 120 HOH   HOH A . 
U 8 HOH   115 1115 571 HOH   HOH A . 
U 8 HOH   116 1116 428 HOH   HOH A . 
U 8 HOH   117 1117 316 HOH   HOH A . 
U 8 HOH   118 1118 456 HOH   HOH A . 
U 8 HOH   119 1119 618 HOH   HOH A . 
U 8 HOH   120 1120 40  HOH   HOH A . 
U 8 HOH   121 1121 147 HOH   HOH A . 
U 8 HOH   122 1122 372 HOH   HOH A . 
U 8 HOH   123 1123 470 HOH   HOH A . 
U 8 HOH   124 1124 337 HOH   HOH A . 
U 8 HOH   125 1125 263 HOH   HOH A . 
U 8 HOH   126 1126 131 HOH   HOH A . 
U 8 HOH   127 1127 572 HOH   HOH A . 
U 8 HOH   128 1128 567 HOH   HOH A . 
U 8 HOH   129 1129 381 HOH   HOH A . 
U 8 HOH   130 1130 104 HOH   HOH A . 
U 8 HOH   131 1131 272 HOH   HOH A . 
U 8 HOH   132 1132 392 HOH   HOH A . 
U 8 HOH   133 1133 520 HOH   HOH A . 
U 8 HOH   134 1134 230 HOH   HOH A . 
U 8 HOH   135 1135 388 HOH   HOH A . 
U 8 HOH   136 1136 285 HOH   HOH A . 
U 8 HOH   137 1137 6   HOH   HOH A . 
U 8 HOH   138 1138 30  HOH   HOH A . 
U 8 HOH   139 1139 378 HOH   HOH A . 
U 8 HOH   140 1140 433 HOH   HOH A . 
U 8 HOH   141 1141 101 HOH   HOH A . 
U 8 HOH   142 1142 208 HOH   HOH A . 
U 8 HOH   143 1143 545 HOH   HOH A . 
U 8 HOH   144 1144 426 HOH   HOH A . 
U 8 HOH   145 1145 590 HOH   HOH A . 
U 8 HOH   146 1146 44  HOH   HOH A . 
U 8 HOH   147 1147 205 HOH   HOH A . 
U 8 HOH   148 1148 450 HOH   HOH A . 
U 8 HOH   149 1149 414 HOH   HOH A . 
U 8 HOH   150 1150 267 HOH   HOH A . 
U 8 HOH   151 1151 153 HOH   HOH A . 
U 8 HOH   152 1152 117 HOH   HOH A . 
U 8 HOH   153 1153 384 HOH   HOH A . 
U 8 HOH   154 1154 183 HOH   HOH A . 
U 8 HOH   155 1155 574 HOH   HOH A . 
U 8 HOH   156 1156 531 HOH   HOH A . 
U 8 HOH   157 1157 298 HOH   HOH A . 
U 8 HOH   158 1158 23  HOH   HOH A . 
U 8 HOH   159 1159 551 HOH   HOH A . 
U 8 HOH   160 1160 466 HOH   HOH A . 
U 8 HOH   161 1161 60  HOH   HOH A . 
U 8 HOH   162 1162 435 HOH   HOH A . 
U 8 HOH   163 1163 102 HOH   HOH A . 
U 8 HOH   164 1164 38  HOH   HOH A . 
U 8 HOH   165 1165 580 HOH   HOH A . 
U 8 HOH   166 1166 495 HOH   HOH A . 
U 8 HOH   167 1167 349 HOH   HOH A . 
U 8 HOH   168 1168 186 HOH   HOH A . 
U 8 HOH   169 1169 37  HOH   HOH A . 
U 8 HOH   170 1170 336 HOH   HOH A . 
U 8 HOH   171 1171 458 HOH   HOH A . 
U 8 HOH   172 1172 460 HOH   HOH A . 
U 8 HOH   173 1173 270 HOH   HOH A . 
U 8 HOH   174 1174 231 HOH   HOH A . 
U 8 HOH   175 1175 157 HOH   HOH A . 
U 8 HOH   176 1176 561 HOH   HOH A . 
U 8 HOH   177 1177 555 HOH   HOH A . 
U 8 HOH   178 1178 3   HOH   HOH A . 
U 8 HOH   179 1179 462 HOH   HOH A . 
U 8 HOH   180 1180 248 HOH   HOH A . 
U 8 HOH   181 1181 229 HOH   HOH A . 
U 8 HOH   182 1182 222 HOH   HOH A . 
U 8 HOH   183 1183 173 HOH   HOH A . 
U 8 HOH   184 1184 560 HOH   HOH A . 
U 8 HOH   185 1185 416 HOH   HOH A . 
U 8 HOH   186 1186 294 HOH   HOH A . 
U 8 HOH   187 1187 13  HOH   HOH A . 
U 8 HOH   188 1188 513 HOH   HOH A . 
U 8 HOH   189 1189 579 HOH   HOH A . 
U 8 HOH   190 1190 34  HOH   HOH A . 
U 8 HOH   191 1191 478 HOH   HOH A . 
U 8 HOH   192 1192 45  HOH   HOH A . 
U 8 HOH   193 1193 322 HOH   HOH A . 
U 8 HOH   194 1194 604 HOH   HOH A . 
U 8 HOH   195 1195 305 HOH   HOH A . 
U 8 HOH   196 1196 244 HOH   HOH A . 
U 8 HOH   197 1197 357 HOH   HOH A . 
U 8 HOH   198 1198 64  HOH   HOH A . 
U 8 HOH   199 1199 141 HOH   HOH A . 
U 8 HOH   200 1200 600 HOH   HOH A . 
U 8 HOH   201 1201 489 HOH   HOH A . 
U 8 HOH   202 1202 506 HOH   HOH A . 
U 8 HOH   203 1203 262 HOH   HOH A . 
U 8 HOH   204 1204 133 HOH   HOH A . 
U 8 HOH   205 1205 313 HOH   HOH A . 
U 8 HOH   206 1206 498 HOH   HOH A . 
U 8 HOH   207 1207 546 HOH   HOH A . 
U 8 HOH   208 1208 587 HOH   HOH A . 
U 8 HOH   209 1209 563 HOH   HOH A . 
U 8 HOH   210 1210 558 HOH   HOH A . 
U 8 HOH   211 1211 610 HOH   HOH A . 
U 8 HOH   212 1212 146 HOH   HOH A . 
U 8 HOH   213 1213 599 HOH   HOH A . 
U 8 HOH   214 1214 362 HOH   HOH A . 
U 8 HOH   215 1215 363 HOH   HOH A . 
U 8 HOH   216 1216 521 HOH   HOH A . 
U 8 HOH   217 1217 202 HOH   HOH A . 
U 8 HOH   218 1218 556 HOH   HOH A . 
U 8 HOH   219 1219 602 HOH   HOH A . 
U 8 HOH   220 1220 550 HOH   HOH A . 
U 8 HOH   221 1221 609 HOH   HOH A . 
V 8 HOH   1   301  441 HOH   HOH E . 
V 8 HOH   2   302  297 HOH   HOH E . 
V 8 HOH   3   303  503 HOH   HOH E . 
V 8 HOH   4   304  354 HOH   HOH E . 
V 8 HOH   5   305  228 HOH   HOH E . 
V 8 HOH   6   306  53  HOH   HOH E . 
V 8 HOH   7   307  525 HOH   HOH E . 
V 8 HOH   8   308  611 HOH   HOH E . 
V 8 HOH   9   309  68  HOH   HOH E . 
V 8 HOH   10  310  42  HOH   HOH E . 
V 8 HOH   11  311  406 HOH   HOH E . 
V 8 HOH   12  312  70  HOH   HOH E . 
V 8 HOH   13  313  84  HOH   HOH E . 
V 8 HOH   14  314  490 HOH   HOH E . 
V 8 HOH   15  315  612 HOH   HOH E . 
V 8 HOH   16  316  437 HOH   HOH E . 
V 8 HOH   17  317  494 HOH   HOH E . 
V 8 HOH   18  318  88  HOH   HOH E . 
V 8 HOH   19  319  581 HOH   HOH E . 
V 8 HOH   20  320  568 HOH   HOH E . 
V 8 HOH   21  321  275 HOH   HOH E . 
V 8 HOH   22  322  329 HOH   HOH E . 
W 8 HOH   1   301  486 HOH   HOH F . 
W 8 HOH   2   302  312 HOH   HOH F . 
W 8 HOH   3   303  335 HOH   HOH F . 
W 8 HOH   4   304  251 HOH   HOH F . 
W 8 HOH   5   305  396 HOH   HOH F . 
W 8 HOH   6   306  427 HOH   HOH F . 
W 8 HOH   7   307  122 HOH   HOH F . 
W 8 HOH   8   308  201 HOH   HOH F . 
W 8 HOH   9   309  475 HOH   HOH F . 
W 8 HOH   10  310  125 HOH   HOH F . 
W 8 HOH   11  311  310 HOH   HOH F . 
W 8 HOH   12  312  220 HOH   HOH F . 
W 8 HOH   13  313  617 HOH   HOH F . 
W 8 HOH   14  314  149 HOH   HOH F . 
W 8 HOH   15  315  165 HOH   HOH F . 
W 8 HOH   16  316  111 HOH   HOH F . 
W 8 HOH   17  317  377 HOH   HOH F . 
W 8 HOH   18  318  163 HOH   HOH F . 
W 8 HOH   19  319  447 HOH   HOH F . 
W 8 HOH   20  320  121 HOH   HOH F . 
W 8 HOH   21  321  43  HOH   HOH F . 
W 8 HOH   22  322  57  HOH   HOH F . 
W 8 HOH   23  323  374 HOH   HOH F . 
W 8 HOH   24  324  160 HOH   HOH F . 
W 8 HOH   25  325  137 HOH   HOH F . 
W 8 HOH   26  326  255 HOH   HOH F . 
W 8 HOH   27  327  615 HOH   HOH F . 
W 8 HOH   28  328  613 HOH   HOH F . 
W 8 HOH   29  329  364 HOH   HOH F . 
W 8 HOH   30  330  260 HOH   HOH F . 
X 8 HOH   1   1001 360 HOH   HOH D . 
X 8 HOH   2   1002 261 HOH   HOH D . 
X 8 HOH   3   1003 465 HOH   HOH D . 
X 8 HOH   4   1004 529 HOH   HOH D . 
X 8 HOH   5   1005 578 HOH   HOH D . 
X 8 HOH   6   1006 35  HOH   HOH D . 
X 8 HOH   7   1007 476 HOH   HOH D . 
X 8 HOH   8   1008 268 HOH   HOH D . 
X 8 HOH   9   1009 540 HOH   HOH D . 
X 8 HOH   10  1010 566 HOH   HOH D . 
X 8 HOH   11  1011 223 HOH   HOH D . 
X 8 HOH   12  1012 400 HOH   HOH D . 
X 8 HOH   13  1013 245 HOH   HOH D . 
X 8 HOH   14  1014 46  HOH   HOH D . 
X 8 HOH   15  1015 74  HOH   HOH D . 
X 8 HOH   16  1016 142 HOH   HOH D . 
X 8 HOH   17  1017 472 HOH   HOH D . 
X 8 HOH   18  1018 324 HOH   HOH D . 
X 8 HOH   19  1019 233 HOH   HOH D . 
X 8 HOH   20  1020 180 HOH   HOH D . 
X 8 HOH   21  1021 457 HOH   HOH D . 
X 8 HOH   22  1022 507 HOH   HOH D . 
X 8 HOH   23  1023 237 HOH   HOH D . 
X 8 HOH   24  1024 145 HOH   HOH D . 
X 8 HOH   25  1025 18  HOH   HOH D . 
X 8 HOH   26  1026 479 HOH   HOH D . 
X 8 HOH   27  1027 277 HOH   HOH D . 
X 8 HOH   28  1028 17  HOH   HOH D . 
X 8 HOH   29  1029 175 HOH   HOH D . 
X 8 HOH   30  1030 95  HOH   HOH D . 
X 8 HOH   31  1031 100 HOH   HOH D . 
X 8 HOH   32  1032 72  HOH   HOH D . 
X 8 HOH   33  1033 419 HOH   HOH D . 
X 8 HOH   34  1034 317 HOH   HOH D . 
X 8 HOH   35  1035 238 HOH   HOH D . 
X 8 HOH   36  1036 383 HOH   HOH D . 
X 8 HOH   37  1037 422 HOH   HOH D . 
X 8 HOH   38  1038 1   HOH   HOH D . 
X 8 HOH   39  1039 534 HOH   HOH D . 
X 8 HOH   40  1040 481 HOH   HOH D . 
X 8 HOH   41  1041 198 HOH   HOH D . 
X 8 HOH   42  1042 341 HOH   HOH D . 
X 8 HOH   43  1043 461 HOH   HOH D . 
X 8 HOH   44  1044 379 HOH   HOH D . 
X 8 HOH   45  1045 386 HOH   HOH D . 
X 8 HOH   46  1046 58  HOH   HOH D . 
X 8 HOH   47  1047 239 HOH   HOH D . 
X 8 HOH   48  1048 282 HOH   HOH D . 
X 8 HOH   49  1049 519 HOH   HOH D . 
X 8 HOH   50  1050 375 HOH   HOH D . 
X 8 HOH   51  1051 423 HOH   HOH D . 
X 8 HOH   52  1052 522 HOH   HOH D . 
X 8 HOH   53  1053 199 HOH   HOH D . 
X 8 HOH   54  1054 127 HOH   HOH D . 
X 8 HOH   55  1055 543 HOH   HOH D . 
X 8 HOH   56  1056 41  HOH   HOH D . 
X 8 HOH   57  1057 97  HOH   HOH D . 
X 8 HOH   58  1058 118 HOH   HOH D . 
X 8 HOH   59  1059 511 HOH   HOH D . 
X 8 HOH   60  1060 54  HOH   HOH D . 
X 8 HOH   61  1061 328 HOH   HOH D . 
X 8 HOH   62  1062 286 HOH   HOH D . 
X 8 HOH   63  1063 398 HOH   HOH D . 
X 8 HOH   64  1064 85  HOH   HOH D . 
X 8 HOH   65  1065 24  HOH   HOH D . 
X 8 HOH   66  1066 524 HOH   HOH D . 
X 8 HOH   67  1067 395 HOH   HOH D . 
X 8 HOH   68  1068 176 HOH   HOH D . 
X 8 HOH   69  1069 188 HOH   HOH D . 
X 8 HOH   70  1070 320 HOH   HOH D . 
X 8 HOH   71  1071 181 HOH   HOH D . 
X 8 HOH   72  1072 219 HOH   HOH D . 
X 8 HOH   73  1073 596 HOH   HOH D . 
X 8 HOH   74  1074 434 HOH   HOH D . 
X 8 HOH   75  1075 128 HOH   HOH D . 
X 8 HOH   76  1076 547 HOH   HOH D . 
X 8 HOH   77  1077 73  HOH   HOH D . 
X 8 HOH   78  1078 51  HOH   HOH D . 
X 8 HOH   79  1079 523 HOH   HOH D . 
X 8 HOH   80  1080 276 HOH   HOH D . 
X 8 HOH   81  1081 370 HOH   HOH D . 
X 8 HOH   82  1082 207 HOH   HOH D . 
X 8 HOH   83  1083 126 HOH   HOH D . 
X 8 HOH   84  1084 10  HOH   HOH D . 
X 8 HOH   85  1085 439 HOH   HOH D . 
X 8 HOH   86  1086 152 HOH   HOH D . 
X 8 HOH   87  1087 508 HOH   HOH D . 
X 8 HOH   88  1088 232 HOH   HOH D . 
X 8 HOH   89  1089 79  HOH   HOH D . 
X 8 HOH   90  1090 75  HOH   HOH D . 
X 8 HOH   91  1091 2   HOH   HOH D . 
X 8 HOH   92  1092 139 HOH   HOH D . 
X 8 HOH   93  1093 582 HOH   HOH D . 
X 8 HOH   94  1094 283 HOH   HOH D . 
X 8 HOH   95  1095 299 HOH   HOH D . 
X 8 HOH   96  1096 112 HOH   HOH D . 
X 8 HOH   97  1097 76  HOH   HOH D . 
X 8 HOH   98  1098 156 HOH   HOH D . 
X 8 HOH   99  1099 430 HOH   HOH D . 
X 8 HOH   100 1100 583 HOH   HOH D . 
X 8 HOH   101 1101 187 HOH   HOH D . 
X 8 HOH   102 1102 274 HOH   HOH D . 
X 8 HOH   103 1103 59  HOH   HOH D . 
X 8 HOH   104 1104 136 HOH   HOH D . 
X 8 HOH   105 1105 235 HOH   HOH D . 
X 8 HOH   106 1106 496 HOH   HOH D . 
X 8 HOH   107 1107 306 HOH   HOH D . 
X 8 HOH   108 1108 373 HOH   HOH D . 
X 8 HOH   109 1109 166 HOH   HOH D . 
X 8 HOH   110 1110 348 HOH   HOH D . 
X 8 HOH   111 1111 549 HOH   HOH D . 
X 8 HOH   112 1112 63  HOH   HOH D . 
X 8 HOH   113 1113 290 HOH   HOH D . 
X 8 HOH   114 1114 14  HOH   HOH D . 
X 8 HOH   115 1115 401 HOH   HOH D . 
X 8 HOH   116 1116 585 HOH   HOH D . 
X 8 HOH   117 1117 124 HOH   HOH D . 
X 8 HOH   118 1118 321 HOH   HOH D . 
X 8 HOH   119 1119 356 HOH   HOH D . 
X 8 HOH   120 1120 455 HOH   HOH D . 
X 8 HOH   121 1121 129 HOH   HOH D . 
X 8 HOH   122 1122 391 HOH   HOH D . 
X 8 HOH   123 1123 421 HOH   HOH D . 
X 8 HOH   124 1124 115 HOH   HOH D . 
X 8 HOH   125 1125 424 HOH   HOH D . 
X 8 HOH   126 1126 536 HOH   HOH D . 
X 8 HOH   127 1127 504 HOH   HOH D . 
X 8 HOH   128 1128 410 HOH   HOH D . 
X 8 HOH   129 1129 453 HOH   HOH D . 
X 8 HOH   130 1130 9   HOH   HOH D . 
X 8 HOH   131 1131 387 HOH   HOH D . 
X 8 HOH   132 1132 71  HOH   HOH D . 
X 8 HOH   133 1133 33  HOH   HOH D . 
X 8 HOH   134 1134 597 HOH   HOH D . 
X 8 HOH   135 1135 93  HOH   HOH D . 
X 8 HOH   136 1136 319 HOH   HOH D . 
X 8 HOH   137 1137 411 HOH   HOH D . 
X 8 HOH   138 1138 278 HOH   HOH D . 
X 8 HOH   139 1139 182 HOH   HOH D . 
X 8 HOH   140 1140 5   HOH   HOH D . 
X 8 HOH   141 1141 284 HOH   HOH D . 
X 8 HOH   142 1142 449 HOH   HOH D . 
X 8 HOH   143 1143 204 HOH   HOH D . 
X 8 HOH   144 1144 468 HOH   HOH D . 
X 8 HOH   145 1145 189 HOH   HOH D . 
X 8 HOH   146 1146 477 HOH   HOH D . 
X 8 HOH   147 1147 502 HOH   HOH D . 
X 8 HOH   148 1148 32  HOH   HOH D . 
X 8 HOH   149 1149 425 HOH   HOH D . 
X 8 HOH   150 1150 82  HOH   HOH D . 
X 8 HOH   151 1151 575 HOH   HOH D . 
X 8 HOH   152 1152 66  HOH   HOH D . 
X 8 HOH   153 1153 151 HOH   HOH D . 
X 8 HOH   154 1154 577 HOH   HOH D . 
X 8 HOH   155 1155 557 HOH   HOH D . 
X 8 HOH   156 1156 404 HOH   HOH D . 
X 8 HOH   157 1157 559 HOH   HOH D . 
X 8 HOH   158 1158 67  HOH   HOH D . 
X 8 HOH   159 1159 570 HOH   HOH D . 
X 8 HOH   160 1160 155 HOH   HOH D . 
X 8 HOH   161 1161 586 HOH   HOH D . 
X 8 HOH   162 1162 440 HOH   HOH D . 
X 8 HOH   163 1163 159 HOH   HOH D . 
X 8 HOH   164 1164 197 HOH   HOH D . 
X 8 HOH   165 1165 26  HOH   HOH D . 
X 8 HOH   166 1166 48  HOH   HOH D . 
X 8 HOH   167 1167 382 HOH   HOH D . 
X 8 HOH   168 1168 304 HOH   HOH D . 
X 8 HOH   169 1169 564 HOH   HOH D . 
X 8 HOH   170 1170 25  HOH   HOH D . 
X 8 HOH   171 1171 185 HOH   HOH D . 
X 8 HOH   172 1172 594 HOH   HOH D . 
X 8 HOH   173 1173 459 HOH   HOH D . 
X 8 HOH   174 1174 603 HOH   HOH D . 
X 8 HOH   175 1175 452 HOH   HOH D . 
X 8 HOH   176 1176 526 HOH   HOH D . 
X 8 HOH   177 1177 130 HOH   HOH D . 
X 8 HOH   178 1178 172 HOH   HOH D . 
X 8 HOH   179 1179 21  HOH   HOH D . 
X 8 HOH   180 1180 601 HOH   HOH D . 
X 8 HOH   181 1181 116 HOH   HOH D . 
X 8 HOH   182 1182 390 HOH   HOH D . 
X 8 HOH   183 1183 77  HOH   HOH D . 
X 8 HOH   184 1184 27  HOH   HOH D . 
X 8 HOH   185 1185 209 HOH   HOH D . 
X 8 HOH   186 1186 500 HOH   HOH D . 
X 8 HOH   187 1187 150 HOH   HOH D . 
X 8 HOH   188 1188 365 HOH   HOH D . 
X 8 HOH   189 1189 311 HOH   HOH D . 
X 8 HOH   190 1190 413 HOH   HOH D . 
X 8 HOH   191 1191 591 HOH   HOH D . 
X 8 HOH   192 1192 91  HOH   HOH D . 
X 8 HOH   193 1193 584 HOH   HOH D . 
X 8 HOH   194 1194 509 HOH   HOH D . 
X 8 HOH   195 1195 330 HOH   HOH D . 
X 8 HOH   196 1196 541 HOH   HOH D . 
X 8 HOH   197 1197 303 HOH   HOH D . 
X 8 HOH   198 1198 62  HOH   HOH D . 
X 8 HOH   199 1199 113 HOH   HOH D . 
X 8 HOH   200 1200 499 HOH   HOH D . 
X 8 HOH   201 1201 432 HOH   HOH D . 
X 8 HOH   202 1202 616 HOH   HOH D . 
X 8 HOH   203 1203 528 HOH   HOH D . 
X 8 HOH   204 1204 562 HOH   HOH D . 
X 8 HOH   205 1205 224 HOH   HOH D . 
X 8 HOH   206 1206 598 HOH   HOH D . 
X 8 HOH   207 1207 247 HOH   HOH D . 
X 8 HOH   208 1208 340 HOH   HOH D . 
X 8 HOH   209 1209 614 HOH   HOH D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 C DA  202 ? "O5'" ? B DA  1   "O5'" 
2  1 Y 1 A ARG 736 ? CG    ? C ARG 443 CG    
3  1 Y 1 A ARG 736 ? CD    ? C ARG 443 CD    
4  1 Y 1 A ARG 736 ? NE    ? C ARG 443 NE    
5  1 Y 1 A ARG 736 ? CZ    ? C ARG 443 CZ    
6  1 Y 1 A ARG 736 ? NH1   ? C ARG 443 NH1   
7  1 Y 1 A ARG 736 ? NH2   ? C ARG 443 NH2   
8  1 Y 1 A LYS 793 ? CG    ? C LYS 500 CG    
9  1 Y 1 A LYS 793 ? CD    ? C LYS 500 CD    
10 1 Y 1 A LYS 793 ? CE    ? C LYS 500 CE    
11 1 Y 1 A LYS 793 ? NZ    ? C LYS 500 NZ    
12 1 Y 1 F DA  202 ? "O5'" ? E DA  1   "O5'" 
13 1 Y 1 D GLU 295 ? CG    ? F GLU 2   CG    
14 1 Y 1 D GLU 295 ? CD    ? F GLU 2   CD    
15 1 Y 1 D GLU 295 ? OE1   ? F GLU 2   OE1   
16 1 Y 1 D GLU 295 ? OE2   ? F GLU 2   OE2   
17 1 Y 1 D ARG 736 ? CG    ? F ARG 443 CG    
18 1 Y 1 D ARG 736 ? CD    ? F ARG 443 CD    
19 1 Y 1 D ARG 736 ? NE    ? F ARG 443 NE    
20 1 Y 1 D ARG 736 ? CZ    ? F ARG 443 CZ    
21 1 Y 1 D ARG 736 ? NH1   ? F ARG 443 NH1   
22 1 Y 1 D ARG 736 ? NH2   ? F ARG 443 NH2   
23 1 Y 1 D LYS 793 ? CG    ? F LYS 500 CG    
24 1 Y 1 D LYS 793 ? CD    ? F LYS 500 CD    
25 1 Y 1 D LYS 793 ? CE    ? F LYS 500 CE    
26 1 Y 1 D LYS 793 ? NZ    ? F LYS 500 NZ    
27 1 N 1 A PEG 904 ? O1    ? K PEG 1   O1    
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC    ? ? ? 5.8.0352 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-3000  ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? SCALEPACK ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER    ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8XK9 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     105.986 
_cell.length_a_esd                 ? 
_cell.length_b                     105.986 
_cell.length_b_esd                 ? 
_cell.length_c                     191.722 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8XK9 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                78 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 43' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8XK9 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.88 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          68.30 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M HEPES pH 7.5, 10% propanol, and 20% PEG 4000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            289 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-10-07 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.979 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL18U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.979 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL18U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8XK9 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.40 
_reflns.d_resolution_low                               50.00 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     82487 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.8 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          5.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.616 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.142 
_reflns.pdbx_Rpim_I_all                                0.054 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       561436 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.982 
_reflns.pdbx_CC_star                                   0.995 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.132 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
2.40 2.44  ? ? ? ? ? ? 4102 ? ? ? ? ? ? ? ? ? ? ? 6.4 0.562 ? ? 0.673 0.263 ? 1  1 0.867 0.964 ? 100.0 ? 0.619 ? ? ? ? ? ? ? ? ? 
2.44 2.49  ? ? ? ? ? ? 4133 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.571 ? ? 0.609 0.230 ? 2  1 0.896 0.972 ? 100.0 ? 0.563 ? ? ? ? ? ? ? ? ? 
2.49 2.53  ? ? ? ? ? ? 4090 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.618 ? ? 0.520 0.197 ? 3  1 0.921 0.979 ? 100.0 ? 0.480 ? ? ? ? ? ? ? ? ? 
2.53 2.59  ? ? ? ? ? ? 4176 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.642 ? ? 0.464 0.175 ? 4  1 0.930 0.982 ? 100.0 ? 0.429 ? ? ? ? ? ? ? ? ? 
2.59 2.64  ? ? ? ? ? ? 4090 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.672 ? ? 0.425 0.161 ? 5  1 0.940 0.984 ? 100.0 ? 0.393 ? ? ? ? ? ? ? ? ? 
2.64 2.70  ? ? ? ? ? ? 4079 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.740 ? ? 0.365 0.138 ? 6  1 0.948 0.987 ? 100.0 ? 0.338 ? ? ? ? ? ? ? ? ? 
2.70 2.77  ? ? ? ? ? ? 4117 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.784 ? ? 0.334 0.126 ? 7  1 0.957 0.989 ? 100.0 ? 0.309 ? ? ? ? ? ? ? ? ? 
2.77 2.85  ? ? ? ? ? ? 4136 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.864 ? ? 0.292 0.110 ? 8  1 0.965 0.991 ? 100.0 ? 0.270 ? ? ? ? ? ? ? ? ? 
2.85 2.93  ? ? ? ? ? ? 4135 ? ? ? ? ? ? ? ? ? ? ? 7.0 0.967 ? ? 0.254 0.095 ? 9  1 0.974 0.993 ? 100.0 ? 0.235 ? ? ? ? ? ? ? ? ? 
2.93 3.02  ? ? ? ? ? ? 4086 ? ? ? ? ? ? ? ? ? ? ? 6.9 1.151 ? ? 0.226 0.086 ? 10 1 0.973 0.993 ? 100.0 ? 0.209 ? ? ? ? ? ? ? ? ? 
3.02 3.13  ? ? ? ? ? ? 4143 ? ? ? ? ? ? ? ? ? ? ? 6.8 1.337 ? ? 0.200 0.076 ? 11 1 0.977 0.994 ? 100.0 ? 0.184 ? ? ? ? ? ? ? ? ? 
3.13 3.26  ? ? ? ? ? ? 4093 ? ? ? ? ? ? ? ? ? ? ? 6.7 1.729 ? ? 0.177 0.068 ? 12 1 0.982 0.995 ? 100.0 ? 0.164 ? ? ? ? ? ? ? ? ? 
3.26 3.41  ? ? ? ? ? ? 4106 ? ? ? ? ? ? ? ? ? ? ? 6.1 2.067 ? ? 0.158 0.064 ? 13 1 0.984 0.996 ? 99.8  ? 0.145 ? ? ? ? ? ? ? ? ? 
3.41 3.58  ? ? ? ? ? ? 4151 ? ? ? ? ? ? ? ? ? ? ? 6.2 2.570 ? ? 0.149 0.059 ? 14 1 0.985 0.996 ? 100.0 ? 0.136 ? ? ? ? ? ? ? ? ? 
3.58 3.81  ? ? ? ? ? ? 4124 ? ? ? ? ? ? ? ? ? ? ? 7.3 2.798 ? ? 0.136 0.050 ? 15 1 0.988 0.997 ? 100.0 ? 0.126 ? ? ? ? ? ? ? ? ? 
3.81 4.10  ? ? ? ? ? ? 4117 ? ? ? ? ? ? ? ? ? ? ? 7.3 3.099 ? ? 0.127 0.047 ? 16 1 0.991 0.998 ? 100.0 ? 0.118 ? ? ? ? ? ? ? ? ? 
4.10 4.52  ? ? ? ? ? ? 4127 ? ? ? ? ? ? ? ? ? ? ? 7.2 3.245 ? ? 0.116 0.043 ? 17 1 0.991 0.998 ? 99.9  ? 0.108 ? ? ? ? ? ? ? ? ? 
4.52 5.17  ? ? ? ? ? ? 4157 ? ? ? ? ? ? ? ? ? ? ? 7.0 2.848 ? ? 0.106 0.040 ? 18 1 0.993 0.998 ? 99.9  ? 0.098 ? ? ? ? ? ? ? ? ? 
5.17 6.51  ? ? ? ? ? ? 4128 ? ? ? ? ? ? ? ? ? ? ? 6.4 2.276 ? ? 0.101 0.039 ? 19 1 0.992 0.998 ? 99.8  ? 0.093 ? ? ? ? ? ? ? ? ? 
6.51 50.00 ? ? ? ? ? ? 4197 ? ? ? ? ? ? ? ? ? ? ? 6.6 2.674 ? ? 0.090 0.035 ? 20 1 0.993 0.998 ? 99.4  ? 0.083 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            -0.18 
_refine.aniso_B[1][2]                            -0.00 
_refine.aniso_B[1][3]                            0.00 
_refine.aniso_B[2][2]                            -0.18 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            0.35 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               44.470 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.959 
_refine.correlation_coeff_Fo_to_Fc_free          0.943 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8XK9 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.40 
_refine.ls_d_res_low                             38.10 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     78293 
_refine.ls_number_reflns_R_free                  4146 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.85 
_refine.ls_percent_reflns_R_free                 5.0 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.17934 
_refine.ls_R_factor_R_free                       0.21791 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.17740 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.229 
_refine.pdbx_overall_ESU_R_Free                  0.193 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             5.753 
_refine.overall_SU_ML                            0.132 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.40 
_refine_hist.d_res_low                        38.10 
_refine_hist.number_atoms_solvent             537 
_refine_hist.number_atoms_total               10283 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        8513 
_refine_hist.pdbx_number_atoms_nucleic_acid   1138 
_refine_hist.pdbx_number_atoms_ligand         95 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.007  0.012  10128 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.016  8878  ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 1.447  1.668  13948 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 0.438  1.548  20650 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.184  5.000  1085  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 21.096 10.000 109   ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 16.613 10.000 1519  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.079  0.200  1533  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.006  0.020  10937 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  2001  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 3.199  4.555  4325  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 3.195  4.555  4325  ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 4.669  6.835  5412  ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 4.669  6.835  5413  ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 4.207  5.071  5803  ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 4.199  5.065  5796  ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 6.382  7.481  8524  ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 8.201  57.661 11750 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 8.201  57.668 11751 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.4 
_refine_ls_shell.d_res_low                        2.460 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             328 
_refine_ls_shell.number_reflns_R_work             5729 
_refine_ls_shell.percent_reflns_obs               99.33 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.243 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   ? 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.255 
# 
_struct.entry_id                     8XK9 
_struct.title                        'ternary complex of DNA polymerase SFM4-3 recognizing C2 methyoxy nucleotide' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8XK9 
_struct_keywords.text            'DNA polymerase, DNA BINDING PROTEIN' 
_struct_keywords.pdbx_keywords   'DNA BINDING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 1 ? 
E N N 2 ? 
F N N 3 ? 
G N N 4 ? 
H N N 4 ? 
I N N 4 ? 
J N N 5 ? 
K N N 6 ? 
L N N 7 ? 
M N N 4 ? 
N N N 4 ? 
O N N 4 ? 
P N N 5 ? 
Q N N 6 ? 
R N N 7 ? 
S N N 8 ? 
T N N 8 ? 
U N N 8 ? 
V N N 8 ? 
W N N 8 ? 
X N N 8 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8XK9       8XK9   ? 1 ? 1   
2 PDB 8XK9       8XK9   ? 2 ? 1   
3 UNP DPO1_THEAQ P19821 ? 3 
;LEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDP
MLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDV
AYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKIL
QYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYSQ
IELRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVDPLMRRAAKTINFGVLYGMSAHRLSQELAIPYEEAQAFI
ERYFQSFPKVRAWIEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLE
EMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAKE
;
294 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8XK9 B 1 ? 12  ? 8XK9   101 ? 112 ? 101 112 
2 2 8XK9 C 1 ? 16  ? 8XK9   202 ? 217 ? 202 217 
3 3 8XK9 A 1 ? 539 ? P19821 294 ? 832 ? 294 832 
4 1 8XK9 E 1 ? 12  ? 8XK9   101 ? 112 ? 101 112 
5 2 8XK9 F 1 ? 16  ? 8XK9   202 ? 217 ? 202 217 
6 3 8XK9 D 1 ? 539 ? P19821 294 ? 832 ? 294 832 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 8XK9 MET A 1   ? UNP P19821 LEU 294 conflict 294 1  
3 8XK9 ALA A 225 ? UNP P19821 VAL 518 conflict 518 2  
3 8XK9 SER A 290 ? UNP P19821 ASN 583 conflict 583 3  
3 8XK9 GLU A 321 ? UNP P19821 ILE 614 conflict 614 4  
3 8XK9 GLY A 322 ? UNP P19821 GLU 615 conflict 615 5  
3 8XK9 ASN A 362 ? UNP P19821 ASP 655 conflict 655 6  
3 8XK9 LYS A 388 ? UNP P19821 GLU 681 conflict 681 7  
3 8XK9 GLN A 449 ? UNP P19821 GLU 742 conflict 742 8  
3 8XK9 ARG A 454 ? UNP P19821 MET 747 conflict 747 9  
6 8XK9 MET D 1   ? UNP P19821 LEU 294 conflict 294 10 
6 8XK9 ALA D 225 ? UNP P19821 VAL 518 conflict 518 11 
6 8XK9 SER D 290 ? UNP P19821 ASN 583 conflict 583 12 
6 8XK9 GLU D 321 ? UNP P19821 ILE 614 conflict 614 13 
6 8XK9 GLY D 322 ? UNP P19821 GLU 615 conflict 615 14 
6 8XK9 ASN D 362 ? UNP P19821 ASP 655 conflict 655 15 
6 8XK9 LYS D 388 ? UNP P19821 GLU 681 conflict 681 16 
6 8XK9 GLN D 449 ? UNP P19821 GLU 742 conflict 742 17 
6 8XK9 ARG D 454 ? UNP P19821 MET 747 conflict 747 18 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLU C 44  ? LEU C 49  ? GLU A 337 LEU A 342 1 ? 6  
HELX_P HELX_P2  AA2 ARG C 50  ? LEU C 52  ? ARG A 343 LEU A 345 5 ? 3  
HELX_P HELX_P3  AA3 LEU C 59  ? GLU C 70  ? LEU A 352 GLU A 363 1 ? 12 
HELX_P HELX_P4  AA4 ASP C 79  ? ASP C 88  ? ASP A 372 ASP A 381 1 ? 10 
HELX_P HELX_P5  AA5 THR C 93  ? GLY C 102 ? THR A 386 GLY A 395 1 ? 10 
HELX_P HELX_P6  AA6 GLU C 108 ? LEU C 127 ? GLU A 401 LEU A 420 1 ? 20 
HELX_P HELX_P7  AA7 GLU C 130 ? VAL C 140 ? GLU A 423 VAL A 433 1 ? 11 
HELX_P HELX_P8  AA8 VAL C 140 ? GLY C 155 ? VAL A 433 GLY A 448 1 ? 16 
HELX_P HELX_P9  AA9 ASP C 159 ? GLY C 186 ? ASP A 452 GLY A 479 1 ? 28 
HELX_P HELX_P10 AB1 SER C 193 ? ASP C 203 ? SER A 486 ASP A 496 1 ? 11 
HELX_P HELX_P11 AB2 SER C 222 ? GLU C 227 ? SER A 515 GLU A 520 1 ? 6  
HELX_P HELX_P12 AB3 HIS C 233 ? TYR C 252 ? HIS A 526 TYR A 545 1 ? 20 
HELX_P HELX_P13 AB4 LEU C 256 ? ILE C 260 ? LEU A 549 ILE A 553 5 ? 5  
HELX_P HELX_P14 AB5 THR C 295 ? ARG C 303 ? THR A 588 ARG A 596 1 ? 9  
HELX_P HELX_P15 AB6 GLN C 320 ? GLY C 331 ? GLN A 613 GLY A 624 1 ? 12 
HELX_P HELX_P16 AB7 ASP C 332 ? GLU C 341 ? ASP A 625 GLU A 634 1 ? 10 
HELX_P HELX_P17 AB8 ASP C 344 ? GLY C 355 ? ASP A 637 GLY A 648 1 ? 12 
HELX_P HELX_P18 AB9 PRO C 357 ? VAL C 361 ? PRO A 650 VAL A 654 5 ? 5  
HELX_P HELX_P19 AC1 ASN C 362 ? TYR C 378 ? ASN A 655 TYR A 671 1 ? 17 
HELX_P HELX_P20 AC2 SER C 381 ? ALA C 390 ? SER A 674 ALA A 683 1 ? 10 
HELX_P HELX_P21 AC3 PRO C 392 ? PHE C 407 ? PRO A 685 PHE A 700 1 ? 16 
HELX_P HELX_P22 AC4 PHE C 407 ? GLY C 425 ? PHE A 700 GLY A 718 1 ? 19 
HELX_P HELX_P23 AC5 VAL C 444 ? GLU C 481 ? VAL A 737 GLU A 774 1 ? 38 
HELX_P HELX_P24 AC6 ARG C 502 ? GLY C 516 ? ARG A 795 GLY A 809 1 ? 15 
HELX_P HELX_P25 AC7 LEU C 535 ? GLU C 539 ? LEU A 828 GLU A 832 5 ? 5  
HELX_P HELX_P26 AC8 GLU F 44  ? LEU F 49  ? GLU D 337 LEU D 342 1 ? 6  
HELX_P HELX_P27 AC9 ARG F 50  ? LEU F 52  ? ARG D 343 LEU D 345 5 ? 3  
HELX_P HELX_P28 AD1 LEU F 59  ? GLU F 70  ? LEU D 352 GLU D 363 1 ? 12 
HELX_P HELX_P29 AD2 ASP F 79  ? ASP F 88  ? ASP D 372 ASP D 381 1 ? 10 
HELX_P HELX_P30 AD3 THR F 93  ? GLY F 102 ? THR D 386 GLY D 395 1 ? 10 
HELX_P HELX_P31 AD4 GLU F 108 ? LEU F 127 ? GLU D 401 LEU D 420 1 ? 20 
HELX_P HELX_P32 AD5 GLU F 130 ? VAL F 140 ? GLU D 423 VAL D 433 1 ? 11 
HELX_P HELX_P33 AD6 VAL F 140 ? GLY F 155 ? VAL D 433 GLY D 448 1 ? 16 
HELX_P HELX_P34 AD7 ASP F 159 ? GLY F 186 ? ASP D 452 GLY D 479 1 ? 28 
HELX_P HELX_P35 AD8 SER F 193 ? ASP F 203 ? SER D 486 ASP D 496 1 ? 11 
HELX_P HELX_P36 AD9 SER F 222 ? GLU F 227 ? SER D 515 GLU D 520 1 ? 6  
HELX_P HELX_P37 AE1 HIS F 233 ? TYR F 252 ? HIS D 526 TYR D 545 1 ? 20 
HELX_P HELX_P38 AE2 LEU F 256 ? ILE F 260 ? LEU D 549 ILE D 553 5 ? 5  
HELX_P HELX_P39 AE3 THR F 295 ? ARG F 303 ? THR D 588 ARG D 596 1 ? 9  
HELX_P HELX_P40 AE4 GLN F 320 ? GLY F 331 ? GLN D 613 GLY D 624 1 ? 12 
HELX_P HELX_P41 AE5 ASP F 332 ? GLU F 341 ? ASP D 625 GLU D 634 1 ? 10 
HELX_P HELX_P42 AE6 ASP F 344 ? GLY F 355 ? ASP D 637 GLY D 648 1 ? 12 
HELX_P HELX_P43 AE7 PRO F 357 ? VAL F 361 ? PRO D 650 VAL D 654 5 ? 5  
HELX_P HELX_P44 AE8 ASN F 362 ? TYR F 378 ? ASN D 655 TYR D 671 1 ? 17 
HELX_P HELX_P45 AE9 SER F 381 ? ALA F 390 ? SER D 674 ALA D 683 1 ? 10 
HELX_P HELX_P46 AF1 PRO F 392 ? PHE F 407 ? PRO D 685 PHE D 700 1 ? 16 
HELX_P HELX_P47 AF2 PHE F 407 ? GLY F 425 ? PHE D 700 GLY D 718 1 ? 19 
HELX_P HELX_P48 AF3 VAL F 444 ? GLU F 481 ? VAL D 737 GLU D 774 1 ? 38 
HELX_P HELX_P49 AF4 ARG F 502 ? GLY F 516 ? ARG D 795 GLY D 809 1 ? 15 
HELX_P HELX_P50 AF5 LEU F 535 ? GLU F 539 ? LEU D 828 GLU D 832 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1  covale both ? A DC  11  "O3'" ? ? ? 1_555 A DOC   12 P   ? ? B DC  111 B DOC   112  1_555 ? ? ? ? ? ? ?            1.591 
? ? 
covale2  covale both ? B DC  15  "O3'" ? ? ? 1_555 B OMG   16 P   ? ? C DC  216 C OMG   217  1_555 ? ? ? ? ? ? ?            1.624 
? ? 
covale3  covale both ? D DC  11  "O3'" ? ? ? 1_555 D DOC   12 P   ? ? E DC  111 E DOC   112  1_555 ? ? ? ? ? ? ?            1.580 
? ? 
covale4  covale both ? E DC  15  "O3'" ? ? ? 1_555 E OMG   16 P   ? ? F DC  216 F OMG   217  1_555 ? ? ? ? ? ? ?            1.626 
? ? 
metalc1  metalc ?    ? G MG  .   MG    ? ? ? 1_555 S HOH   .  O   ? ? B MG  201 B HOH   310  1_555 ? ? ? ? ? ? ?            2.121 
? ? 
metalc2  metalc ?    ? G MG  .   MG    ? ? ? 1_555 S HOH   .  O   ? ? B MG  201 B HOH   312  1_555 ? ? ? ? ? ? ?            2.289 
? ? 
metalc3  metalc ?    ? G MG  .   MG    ? ? ? 1_555 T HOH   .  O   ? ? B MG  201 C HOH   332  1_555 ? ? ? ? ? ? ?            2.253 
? ? 
metalc4  metalc ?    ? G MG  .   MG    ? ? ? 1_555 U HOH   .  O   ? ? B MG  201 A HOH   1221 1_555 ? ? ? ? ? ? ?            2.297 
? ? 
metalc5  metalc ?    ? C ASP 317 OD1   ? ? ? 1_555 H MG    .  MG  ? ? A ASP 610 A MG    901  1_555 ? ? ? ? ? ? ?            2.068 
? ? 
metalc6  metalc ?    ? C ASP 317 OD2   ? ? ? 1_555 I MG    .  MG  ? ? A ASP 610 A MG    902  1_555 ? ? ? ? ? ? ?            2.657 
? ? 
metalc7  metalc ?    ? C TYR 318 O     ? ? ? 1_555 H MG    .  MG  ? ? A TYR 611 A MG    901  1_555 ? ? ? ? ? ? ?            2.175 
? ? 
metalc8  metalc ?    ? C ASP 492 OD2   ? ? ? 1_555 H MG    .  MG  ? ? A ASP 785 A MG    901  1_555 ? ? ? ? ? ? ?            1.991 
? ? 
metalc9  metalc ?    ? C ASP 492 OD1   ? ? ? 1_555 I MG    .  MG  ? ? A ASP 785 A MG    902  1_555 ? ? ? ? ? ? ?            2.139 
? ? 
metalc10 metalc ?    ? H MG  .   MG    ? ? ? 1_555 J A1LWE .  O2A ? ? A MG  901 A A1LWE 903  1_555 ? ? ? ? ? ? ?            2.125 
? ? 
metalc11 metalc ?    ? H MG  .   MG    ? ? ? 1_555 J A1LWE .  O3B ? ? A MG  901 A A1LWE 903  1_555 ? ? ? ? ? ? ?            2.038 
? ? 
metalc12 metalc ?    ? H MG  .   MG    ? ? ? 1_555 J A1LWE .  O2G ? ? A MG  901 A A1LWE 903  1_555 ? ? ? ? ? ? ?            2.034 
? ? 
metalc13 metalc ?    ? I MG  .   MG    ? ? ? 1_555 J A1LWE .  O2A ? ? A MG  902 A A1LWE 903  1_555 ? ? ? ? ? ? ?            2.117 
? ? 
metalc14 metalc ?    ? I MG  .   MG    ? ? ? 1_555 U HOH   .  O   ? ? A MG  902 A HOH   1120 1_555 ? ? ? ? ? ? ?            2.050 
? ? 
metalc15 metalc ?    ? I MG  .   MG    ? ? ? 1_555 U HOH   .  O   ? ? A MG  902 A HOH   1164 1_555 ? ? ? ? ? ? ?            2.109 
? ? 
metalc16 metalc ?    ? M MG  .   MG    ? ? ? 1_555 V HOH   .  O   ? ? E MG  201 E HOH   308  1_555 ? ? ? ? ? ? ?            2.146 
? ? 
metalc17 metalc ?    ? M MG  .   MG    ? ? ? 1_555 V HOH   .  O   ? ? E MG  201 E HOH   315  1_555 ? ? ? ? ? ? ?            2.226 
? ? 
metalc18 metalc ?    ? M MG  .   MG    ? ? ? 1_555 W HOH   .  O   ? ? E MG  201 F HOH   328  1_555 ? ? ? ? ? ? ?            2.225 
? ? 
metalc19 metalc ?    ? M MG  .   MG    ? ? ? 1_555 X HOH   .  O   ? ? E MG  201 D HOH   1209 1_555 ? ? ? ? ? ? ?            2.358 
? ? 
metalc20 metalc ?    ? V HOH .   O     ? ? ? 1_555 O MG    .  MG  ? ? E HOH 310 D MG    902  1_555 ? ? ? ? ? ? ?            2.542 
? ? 
metalc21 metalc ?    ? F ASP 317 OD1   ? ? ? 1_555 N MG    .  MG  ? ? D ASP 610 D MG    901  1_555 ? ? ? ? ? ? ?            2.167 
? ? 
metalc22 metalc ?    ? F ASP 317 OD1   ? ? ? 1_555 O MG    .  MG  ? ? D ASP 610 D MG    902  1_555 ? ? ? ? ? ? ?            2.948 
? ? 
metalc23 metalc ?    ? F ASP 317 OD2   ? ? ? 1_555 O MG    .  MG  ? ? D ASP 610 D MG    902  1_555 ? ? ? ? ? ? ?            2.312 
? ? 
metalc24 metalc ?    ? F TYR 318 O     ? ? ? 1_555 N MG    .  MG  ? ? D TYR 611 D MG    901  1_555 ? ? ? ? ? ? ?            2.366 
? ? 
metalc25 metalc ?    ? F ASP 492 OD2   ? ? ? 1_555 N MG    .  MG  ? ? D ASP 785 D MG    901  1_555 ? ? ? ? ? ? ?            2.007 
? ? 
metalc26 metalc ?    ? F ASP 492 OD1   ? ? ? 1_555 O MG    .  MG  ? ? D ASP 785 D MG    902  1_555 ? ? ? ? ? ? ?            2.402 
? ? 
metalc27 metalc ?    ? N MG  .   MG    ? ? ? 1_555 P A1LWE .  O25 ? ? D MG  901 D A1LWE 903  1_555 ? ? ? ? ? ? ?            2.003 
? ? 
metalc28 metalc ?    ? N MG  .   MG    ? ? ? 1_555 P A1LWE .  O2A ? ? D MG  901 D A1LWE 903  1_555 ? ? ? ? ? ? ?            2.224 
? ? 
metalc29 metalc ?    ? N MG  .   MG    ? ? ? 1_555 P A1LWE .  O3B ? ? D MG  901 D A1LWE 903  1_555 ? ? ? ? ? ? ?            2.113 
? ? 
metalc30 metalc ?    ? O MG  .   MG    ? ? ? 1_555 P A1LWE .  O2A ? ? D MG  902 D A1LWE 903  1_555 ? ? ? ? ? ? ?            2.530 
? ? 
metalc31 metalc ?    ? O MG  .   MG    ? ? ? 1_555 X HOH   .  O   ? ? D MG  902 D HOH   1010 1_555 ? ? ? ? ? ? ?            2.573 
? ? 
hydrog1  hydrog ?    ? A DG  1   N1    ? ? ? 1_555 B DC    15 N3  ? ? B DG  101 C DC    216  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog2  hydrog ?    ? A DG  1   N2    ? ? ? 1_555 B DC    15 O2  ? ? B DG  101 C DC    216  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog3  hydrog ?    ? A DG  1   O6    ? ? ? 1_555 B DC    15 N4  ? ? B DG  101 C DC    216  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog4  hydrog ?    ? A DA  2   N1    ? ? ? 1_555 B DT    14 N3  ? ? B DA  102 C DT    215  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog5  hydrog ?    ? A DA  2   N6    ? ? ? 1_555 B DT    14 O4  ? ? B DA  102 C DT    215  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog6  hydrog ?    ? A DC  3   N3    ? ? ? 1_555 B DG    13 N1  ? ? B DC  103 C DG    214  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog7  hydrog ?    ? A DC  3   N4    ? ? ? 1_555 B DG    13 O6  ? ? B DC  103 C DG    214  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog8  hydrog ?    ? A DC  3   O2    ? ? ? 1_555 B DG    13 N2  ? ? B DC  103 C DG    214  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog9  hydrog ?    ? A DC  4   N3    ? ? ? 1_555 B DG    12 N1  ? ? B DC  104 C DG    213  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog10 hydrog ?    ? A DC  4   N4    ? ? ? 1_555 B DG    12 O6  ? ? B DC  104 C DG    213  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog11 hydrog ?    ? A DC  4   O2    ? ? ? 1_555 B DG    12 N2  ? ? B DC  104 C DG    213  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog12 hydrog ?    ? A DA  5   N1    ? ? ? 1_555 B DT    11 N3  ? ? B DA  105 C DT    212  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog13 hydrog ?    ? A DA  5   N6    ? ? ? 1_555 B DT    11 O4  ? ? B DA  105 C DT    212  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog14 hydrog ?    ? A DC  6   N3    ? ? ? 1_555 B DG    10 N1  ? ? B DC  106 C DG    211  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog15 hydrog ?    ? A DC  6   N4    ? ? ? 1_555 B DG    10 O6  ? ? B DC  106 C DG    211  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog16 hydrog ?    ? A DC  6   O2    ? ? ? 1_555 B DG    10 N2  ? ? B DC  106 C DG    211  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog17 hydrog ?    ? A DG  7   N1    ? ? ? 1_555 B DC    9  N3  ? ? B DG  107 C DC    210  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog18 hydrog ?    ? A DG  7   N2    ? ? ? 1_555 B DC    9  O2  ? ? B DG  107 C DC    210  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog19 hydrog ?    ? A DG  7   O6    ? ? ? 1_555 B DC    9  N4  ? ? B DG  107 C DC    210  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog20 hydrog ?    ? A DG  8   N1    ? ? ? 1_555 B DC    8  N3  ? ? B DG  108 C DC    209  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog21 hydrog ?    ? A DG  8   N2    ? ? ? 1_555 B DC    8  O2  ? ? B DG  108 C DC    209  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog22 hydrog ?    ? A DG  8   O6    ? ? ? 1_555 B DC    8  N4  ? ? B DG  108 C DC    209  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog23 hydrog ?    ? A DC  9   N3    ? ? ? 1_555 B DG    7  N1  ? ? B DC  109 C DG    208  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog24 hydrog ?    ? A DC  9   N4    ? ? ? 1_555 B DG    7  O6  ? ? B DC  109 C DG    208  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog25 hydrog ?    ? A DC  9   O2    ? ? ? 1_555 B DG    7  N2  ? ? B DC  109 C DG    208  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog26 hydrog ?    ? A DG  10  N1    ? ? ? 1_555 B DC    6  N3  ? ? B DG  110 C DC    207  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog27 hydrog ?    ? A DG  10  N2    ? ? ? 1_555 B DC    6  O2  ? ? B DG  110 C DC    207  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog28 hydrog ?    ? A DG  10  O6    ? ? ? 1_555 B DC    6  N4  ? ? B DG  110 C DC    207  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog29 hydrog ?    ? A DC  11  N3    ? ? ? 1_555 B DG    5  N1  ? ? B DC  111 C DG    206  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog30 hydrog ?    ? A DC  11  N4    ? ? ? 1_555 B DG    5  O6  ? ? B DC  111 C DG    206  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog31 hydrog ?    ? A DC  11  O2    ? ? ? 1_555 B DG    5  N2  ? ? B DC  111 C DG    206  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog32 hydrog ?    ? A DOC 12  N3    ? ? ? 1_555 B DG    4  N1  ? ? B DOC 112 C DG    205  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog33 hydrog ?    ? A DOC 12  N4    ? ? ? 1_555 B DG    4  O6  ? ? B DOC 112 C DG    205  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog34 hydrog ?    ? A DOC 12  O2    ? ? ? 1_555 B DG    4  N2  ? ? B DOC 112 C DG    205  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog35 hydrog ?    ? D DG  1   N1    ? ? ? 1_555 E DC    15 N3  ? ? E DG  101 F DC    216  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog36 hydrog ?    ? D DG  1   N2    ? ? ? 1_555 E DC    15 O2  ? ? E DG  101 F DC    216  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog37 hydrog ?    ? D DG  1   O6    ? ? ? 1_555 E DC    15 N4  ? ? E DG  101 F DC    216  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog38 hydrog ?    ? D DA  2   N1    ? ? ? 1_555 E DT    14 N3  ? ? E DA  102 F DT    215  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog39 hydrog ?    ? D DA  2   N6    ? ? ? 1_555 E DT    14 O4  ? ? E DA  102 F DT    215  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog40 hydrog ?    ? D DC  3   N3    ? ? ? 1_555 E DG    13 N1  ? ? E DC  103 F DG    214  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog41 hydrog ?    ? D DC  3   N4    ? ? ? 1_555 E DG    13 O6  ? ? E DC  103 F DG    214  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog42 hydrog ?    ? D DC  3   O2    ? ? ? 1_555 E DG    13 N2  ? ? E DC  103 F DG    214  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog43 hydrog ?    ? D DC  4   N3    ? ? ? 1_555 E DG    12 N1  ? ? E DC  104 F DG    213  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog44 hydrog ?    ? D DC  4   N4    ? ? ? 1_555 E DG    12 O6  ? ? E DC  104 F DG    213  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog45 hydrog ?    ? D DC  4   O2    ? ? ? 1_555 E DG    12 N2  ? ? E DC  104 F DG    213  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog46 hydrog ?    ? D DA  5   N1    ? ? ? 1_555 E DT    11 N3  ? ? E DA  105 F DT    212  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog47 hydrog ?    ? D DA  5   N6    ? ? ? 1_555 E DT    11 O4  ? ? E DA  105 F DT    212  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog48 hydrog ?    ? D DC  6   N3    ? ? ? 1_555 E DG    10 N1  ? ? E DC  106 F DG    211  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog49 hydrog ?    ? D DC  6   N4    ? ? ? 1_555 E DG    10 O6  ? ? E DC  106 F DG    211  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog50 hydrog ?    ? D DC  6   O2    ? ? ? 1_555 E DG    10 N2  ? ? E DC  106 F DG    211  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog51 hydrog ?    ? D DG  7   N1    ? ? ? 1_555 E DC    9  N3  ? ? E DG  107 F DC    210  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog52 hydrog ?    ? D DG  7   N2    ? ? ? 1_555 E DC    9  O2  ? ? E DG  107 F DC    210  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog53 hydrog ?    ? D DG  7   O6    ? ? ? 1_555 E DC    9  N4  ? ? E DG  107 F DC    210  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog54 hydrog ?    ? D DG  8   N1    ? ? ? 1_555 E DC    8  N3  ? ? E DG  108 F DC    209  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog55 hydrog ?    ? D DG  8   N2    ? ? ? 1_555 E DC    8  O2  ? ? E DG  108 F DC    209  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog56 hydrog ?    ? D DG  8   O6    ? ? ? 1_555 E DC    8  N4  ? ? E DG  108 F DC    209  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog57 hydrog ?    ? D DC  9   N3    ? ? ? 1_555 E DG    7  N1  ? ? E DC  109 F DG    208  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog58 hydrog ?    ? D DC  9   N4    ? ? ? 1_555 E DG    7  O6  ? ? E DC  109 F DG    208  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog59 hydrog ?    ? D DC  9   O2    ? ? ? 1_555 E DG    7  N2  ? ? E DC  109 F DG    208  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog60 hydrog ?    ? D DG  10  N1    ? ? ? 1_555 E DC    6  N3  ? ? E DG  110 F DC    207  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog61 hydrog ?    ? D DG  10  N2    ? ? ? 1_555 E DC    6  O2  ? ? E DG  110 F DC    207  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog62 hydrog ?    ? D DG  10  O6    ? ? ? 1_555 E DC    6  N4  ? ? E DG  110 F DC    207  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog63 hydrog ?    ? D DC  11  N3    ? ? ? 1_555 E DG    5  N1  ? ? E DC  111 F DG    206  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog64 hydrog ?    ? D DC  11  N4    ? ? ? 1_555 E DG    5  O6  ? ? E DC  111 F DG    206  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog65 hydrog ?    ? D DC  11  O2    ? ? ? 1_555 E DG    5  N2  ? ? E DC  111 F DG    206  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog66 hydrog ?    ? D DOC 12  N3    ? ? ? 1_555 E DG    4  N1  ? ? E DOC 112 F DG    205  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog67 hydrog ?    ? D DOC 12  N4    ? ? ? 1_555 E DG    4  O6  ? ? E DOC 112 F DG    205  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
hydrog68 hydrog ?    ? D DOC 12  O2    ? ? ? 1_555 E DG    4  N2  ? ? E DOC 112 F DG    205  1_555 ? ? ? ? ? ? WATSON-CRICK ?     
? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
covale ? ? 
metalc ? ? 
hydrog ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  O   ? S HOH   .   ? B HOH   310  ? 1_555 MG ? G MG . ? B MG 201 ? 1_555 O   ? S HOH   .   ? B HOH   312  ? 1_555 90.3  ? 
2  O   ? S HOH   .   ? B HOH   310  ? 1_555 MG ? G MG . ? B MG 201 ? 1_555 O   ? T HOH   .   ? C HOH   332  ? 1_555 171.6 ? 
3  O   ? S HOH   .   ? B HOH   312  ? 1_555 MG ? G MG . ? B MG 201 ? 1_555 O   ? T HOH   .   ? C HOH   332  ? 1_555 87.9  ? 
4  O   ? S HOH   .   ? B HOH   310  ? 1_555 MG ? G MG . ? B MG 201 ? 1_555 O   ? U HOH   .   ? A HOH   1221 ? 1_555 84.5  ? 
5  O   ? S HOH   .   ? B HOH   312  ? 1_555 MG ? G MG . ? B MG 201 ? 1_555 O   ? U HOH   .   ? A HOH   1221 ? 1_555 170.3 ? 
6  O   ? T HOH   .   ? C HOH   332  ? 1_555 MG ? G MG . ? B MG 201 ? 1_555 O   ? U HOH   .   ? A HOH   1221 ? 1_555 98.4  ? 
7  OD1 ? C ASP   317 ? A ASP   610  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 O   ? C TYR   318 ? A TYR   611  ? 1_555 76.6  ? 
8  OD1 ? C ASP   317 ? A ASP   610  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 OD2 ? C ASP   492 ? A ASP   785  ? 1_555 98.3  ? 
9  O   ? C TYR   318 ? A TYR   611  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 OD2 ? C ASP   492 ? A ASP   785  ? 1_555 87.3  ? 
10 OD1 ? C ASP   317 ? A ASP   610  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 O2A ? J A1LWE .   ? A A1LWE 903  ? 1_555 114.6 ? 
11 O   ? C TYR   318 ? A TYR   611  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 O2A ? J A1LWE .   ? A A1LWE 903  ? 1_555 163.1 ? 
12 OD2 ? C ASP   492 ? A ASP   785  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 O2A ? J A1LWE .   ? A A1LWE 903  ? 1_555 78.8  ? 
13 OD1 ? C ASP   317 ? A ASP   610  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 O3B ? J A1LWE .   ? A A1LWE 903  ? 1_555 169.0 ? 
14 O   ? C TYR   318 ? A TYR   611  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 O3B ? J A1LWE .   ? A A1LWE 903  ? 1_555 97.6  ? 
15 OD2 ? C ASP   492 ? A ASP   785  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 O3B ? J A1LWE .   ? A A1LWE 903  ? 1_555 90.7  ? 
16 O2A ? J A1LWE .   ? A A1LWE 903  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 O3B ? J A1LWE .   ? A A1LWE 903  ? 1_555 73.2  ? 
17 OD1 ? C ASP   317 ? A ASP   610  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 O2G ? J A1LWE .   ? A A1LWE 903  ? 1_555 90.9  ? 
18 O   ? C TYR   318 ? A TYR   611  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 O2G ? J A1LWE .   ? A A1LWE 903  ? 1_555 103.2 ? 
19 OD2 ? C ASP   492 ? A ASP   785  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 O2G ? J A1LWE .   ? A A1LWE 903  ? 1_555 167.5 ? 
20 O2A ? J A1LWE .   ? A A1LWE 903  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 O2G ? J A1LWE .   ? A A1LWE 903  ? 1_555 89.7  ? 
21 O3B ? J A1LWE .   ? A A1LWE 903  ? 1_555 MG ? H MG . ? A MG 901 ? 1_555 O2G ? J A1LWE .   ? A A1LWE 903  ? 1_555 81.2  ? 
22 OD2 ? C ASP   317 ? A ASP   610  ? 1_555 MG ? I MG . ? A MG 902 ? 1_555 OD1 ? C ASP   492 ? A ASP   785  ? 1_555 105.0 ? 
23 OD2 ? C ASP   317 ? A ASP   610  ? 1_555 MG ? I MG . ? A MG 902 ? 1_555 O2A ? J A1LWE .   ? A A1LWE 903  ? 1_555 121.4 ? 
24 OD1 ? C ASP   492 ? A ASP   785  ? 1_555 MG ? I MG . ? A MG 902 ? 1_555 O2A ? J A1LWE .   ? A A1LWE 903  ? 1_555 97.3  ? 
25 OD2 ? C ASP   317 ? A ASP   610  ? 1_555 MG ? I MG . ? A MG 902 ? 1_555 O   ? U HOH   .   ? A HOH   1120 ? 1_555 72.4  ? 
26 OD1 ? C ASP   492 ? A ASP   785  ? 1_555 MG ? I MG . ? A MG 902 ? 1_555 O   ? U HOH   .   ? A HOH   1120 ? 1_555 85.0  ? 
27 O2A ? J A1LWE .   ? A A1LWE 903  ? 1_555 MG ? I MG . ? A MG 902 ? 1_555 O   ? U HOH   .   ? A HOH   1120 ? 1_555 164.3 ? 
28 OD2 ? C ASP   317 ? A ASP   610  ? 1_555 MG ? I MG . ? A MG 902 ? 1_555 O   ? U HOH   .   ? A HOH   1164 ? 1_555 88.8  ? 
29 OD1 ? C ASP   492 ? A ASP   785  ? 1_555 MG ? I MG . ? A MG 902 ? 1_555 O   ? U HOH   .   ? A HOH   1164 ? 1_555 157.7 ? 
30 O2A ? J A1LWE .   ? A A1LWE 903  ? 1_555 MG ? I MG . ? A MG 902 ? 1_555 O   ? U HOH   .   ? A HOH   1164 ? 1_555 90.0  ? 
31 O   ? U HOH   .   ? A HOH   1120 ? 1_555 MG ? I MG . ? A MG 902 ? 1_555 O   ? U HOH   .   ? A HOH   1164 ? 1_555 82.5  ? 
32 O   ? V HOH   .   ? E HOH   308  ? 1_555 MG ? M MG . ? E MG 201 ? 1_555 O   ? V HOH   .   ? E HOH   315  ? 1_555 85.3  ? 
33 O   ? V HOH   .   ? E HOH   308  ? 1_555 MG ? M MG . ? E MG 201 ? 1_555 O   ? W HOH   .   ? F HOH   328  ? 1_555 161.7 ? 
34 O   ? V HOH   .   ? E HOH   315  ? 1_555 MG ? M MG . ? E MG 201 ? 1_555 O   ? W HOH   .   ? F HOH   328  ? 1_555 86.9  ? 
35 O   ? V HOH   .   ? E HOH   308  ? 1_555 MG ? M MG . ? E MG 201 ? 1_555 O   ? X HOH   .   ? D HOH   1209 ? 1_555 83.4  ? 
36 O   ? V HOH   .   ? E HOH   315  ? 1_555 MG ? M MG . ? E MG 201 ? 1_555 O   ? X HOH   .   ? D HOH   1209 ? 1_555 151.1 ? 
37 O   ? W HOH   .   ? F HOH   328  ? 1_555 MG ? M MG . ? E MG 201 ? 1_555 O   ? X HOH   .   ? D HOH   1209 ? 1_555 95.6  ? 
38 O   ? V HOH   .   ? E HOH   310  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 OD1 ? F ASP   317 ? D ASP   610  ? 1_555 124.1 ? 
39 O   ? V HOH   .   ? E HOH   310  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 OD2 ? F ASP   317 ? D ASP   610  ? 1_555 98.8  ? 
40 OD1 ? F ASP   317 ? D ASP   610  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 OD2 ? F ASP   317 ? D ASP   610  ? 1_555 48.1  ? 
41 O   ? V HOH   .   ? E HOH   310  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 OD1 ? F ASP   492 ? D ASP   785  ? 1_555 149.4 ? 
42 OD1 ? F ASP   317 ? D ASP   610  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 OD1 ? F ASP   492 ? D ASP   785  ? 1_555 83.1  ? 
43 OD2 ? F ASP   317 ? D ASP   610  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 OD1 ? F ASP   492 ? D ASP   785  ? 1_555 110.9 ? 
44 O   ? V HOH   .   ? E HOH   310  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 O2A ? P A1LWE .   ? D A1LWE 903  ? 1_555 83.9  ? 
45 OD1 ? F ASP   317 ? D ASP   610  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 O2A ? P A1LWE .   ? D A1LWE 903  ? 1_555 86.5  ? 
46 OD2 ? F ASP   317 ? D ASP   610  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 O2A ? P A1LWE .   ? D A1LWE 903  ? 1_555 126.8 ? 
47 OD1 ? F ASP   492 ? D ASP   785  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 O2A ? P A1LWE .   ? D A1LWE 903  ? 1_555 84.1  ? 
48 O   ? V HOH   .   ? E HOH   310  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 O   ? X HOH   .   ? D HOH   1010 ? 1_555 89.1  ? 
49 OD1 ? F ASP   317 ? D ASP   610  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 O   ? X HOH   .   ? D HOH   1010 ? 1_555 121.9 ? 
50 OD2 ? F ASP   317 ? D ASP   610  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 O   ? X HOH   .   ? D HOH   1010 ? 1_555 84.3  ? 
51 OD1 ? F ASP   492 ? D ASP   785  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 O   ? X HOH   .   ? D HOH   1010 ? 1_555 86.8  ? 
52 O2A ? P A1LWE .   ? D A1LWE 903  ? 1_555 MG ? O MG . ? D MG 902 ? 1_555 O   ? X HOH   .   ? D HOH   1010 ? 1_555 148.8 ? 
53 OD1 ? F ASP   317 ? D ASP   610  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 O   ? F TYR   318 ? D TYR   611  ? 1_555 74.4  ? 
54 OD1 ? F ASP   317 ? D ASP   610  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 OD2 ? F ASP   492 ? D ASP   785  ? 1_555 97.3  ? 
55 O   ? F TYR   318 ? D TYR   611  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 OD2 ? F ASP   492 ? D ASP   785  ? 1_555 82.6  ? 
56 OD1 ? F ASP   317 ? D ASP   610  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 O25 ? P A1LWE .   ? D A1LWE 903  ? 1_555 91.4  ? 
57 O   ? F TYR   318 ? D TYR   611  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 O25 ? P A1LWE .   ? D A1LWE 903  ? 1_555 106.2 ? 
58 OD2 ? F ASP   492 ? D ASP   785  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 O25 ? P A1LWE .   ? D A1LWE 903  ? 1_555 169.0 ? 
59 OD1 ? F ASP   317 ? D ASP   610  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 O2A ? P A1LWE .   ? D A1LWE 903  ? 1_555 118.2 ? 
60 O   ? F TYR   318 ? D TYR   611  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 O2A ? P A1LWE .   ? D A1LWE 903  ? 1_555 161.0 ? 
61 OD2 ? F ASP   492 ? D ASP   785  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 O2A ? P A1LWE .   ? D A1LWE 903  ? 1_555 81.7  ? 
62 O25 ? P A1LWE .   ? D A1LWE 903  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 O2A ? P A1LWE .   ? D A1LWE 903  ? 1_555 88.4  ? 
63 OD1 ? F ASP   317 ? D ASP   610  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 O3B ? P A1LWE .   ? D A1LWE 903  ? 1_555 166.0 ? 
64 O   ? F TYR   318 ? D TYR   611  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 O3B ? P A1LWE .   ? D A1LWE 903  ? 1_555 96.7  ? 
65 OD2 ? F ASP   492 ? D ASP   785  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 O3B ? P A1LWE .   ? D A1LWE 903  ? 1_555 92.2  ? 
66 O25 ? P A1LWE .   ? D A1LWE 903  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 O3B ? P A1LWE .   ? D A1LWE 903  ? 1_555 80.5  ? 
67 O2A ? P A1LWE .   ? D A1LWE 903  ? 1_555 MG ? N MG . ? D MG 901 ? 1_555 O3B ? P A1LWE .   ? D A1LWE 903  ? 1_555 73.3  ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 TRP 6   C . ? TRP 299 A PRO 7   C ? PRO 300 A 1 0.74  
2 ASP 285 C . ? ASP 578 A PRO 286 C ? PRO 579 A 1 -4.34 
3 TRP 6   F . ? TRP 299 D PRO 7   F ? PRO 300 D 1 0.76  
4 ASP 285 F . ? ASP 578 D PRO 286 F ? PRO 579 D 1 -3.66 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 4 ? 
AA5 ? 2 ? 
AA6 ? 4 ? 
AA7 ? 2 ? 
AA8 ? 2 ? 
AA9 ? 4 ? 
AB1 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA C 4   ? PRO C 5   ? ALA A 297 PRO A 298 
AA1 2 ARG C 38  ? ARG C 41  ? ARG A 331 ARG A 334 
AA1 3 LEU C 28  ? ARG C 35  ? LEU A 321 ARG A 328 
AA1 4 PHE C 13  ? LEU C 18  ? PHE A 306 LEU A 311 
AA2 1 ARG C 157 ? LEU C 158 ? ARG A 450 LEU A 451 
AA2 2 PHE C 305 ? ILE C 306 ? PHE A 598 ILE A 599 
AA3 1 ARG C 270 ? ASN C 272 ? ARG A 563 ASN A 565 
AA3 2 SER C 282 ? SER C 284 ? SER A 575 SER A 577 
AA4 1 ARG C 485 ? GLN C 489 ? ARG A 778 GLN A 782 
AA4 2 GLU C 493 ? PRO C 499 ? GLU A 786 PRO A 792 
AA4 3 TRP C 311 ? TYR C 318 ? TRP A 604 TYR A 611 
AA4 4 VAL C 526 ? GLY C 531 ? VAL A 819 GLY A 824 
AA5 1 TYR C 426 ? GLU C 428 ? TYR A 719 GLU A 721 
AA5 2 ARG C 434 ? TYR C 436 ? ARG A 727 TYR A 729 
AA6 1 ALA F 4   ? PRO F 5   ? ALA D 297 PRO D 298 
AA6 2 ARG F 38  ? ARG F 41  ? ARG D 331 ARG D 334 
AA6 3 LEU F 28  ? ARG F 35  ? LEU D 321 ARG D 328 
AA6 4 PHE F 13  ? LEU F 18  ? PHE D 306 LEU D 311 
AA7 1 ARG F 157 ? LEU F 158 ? ARG D 450 LEU D 451 
AA7 2 PHE F 305 ? ILE F 306 ? PHE D 598 ILE D 599 
AA8 1 ARG F 270 ? ASN F 272 ? ARG D 563 ASN D 565 
AA8 2 SER F 282 ? SER F 284 ? SER D 575 SER D 577 
AA9 1 ARG F 485 ? GLN F 489 ? ARG D 778 GLN D 782 
AA9 2 GLU F 493 ? PRO F 499 ? GLU D 786 PRO D 792 
AA9 3 TRP F 311 ? TYR F 318 ? TRP D 604 TYR D 611 
AA9 4 VAL F 526 ? GLY F 531 ? VAL D 819 GLY D 824 
AB1 1 TYR F 426 ? GLU F 428 ? TYR D 719 GLU D 721 
AB1 2 ARG F 434 ? TYR F 436 ? ARG D 727 TYR D 729 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ALA C 4   ? N ALA A 297 O ARG C 41  ? O ARG A 334 
AA1 2 3 O HIS C 40  ? O HIS A 333 N ALA C 33  ? N ALA A 326 
AA1 3 4 O ALA C 34  ? O ALA A 327 N PHE C 13  ? N PHE A 306 
AA2 1 2 N ARG C 157 ? N ARG A 450 O ILE C 306 ? O ILE A 599 
AA3 1 2 N ARG C 270 ? N ARG A 563 O SER C 284 ? O SER A 577 
AA4 1 2 N ARG C 485 ? N ARG A 778 O GLU C 497 ? O GLU A 790 
AA4 2 3 O LEU C 496 ? O LEU A 789 N VAL C 314 ? N VAL A 607 
AA4 3 4 N LEU C 313 ? N LEU A 606 O GLY C 531 ? O GLY A 824 
AA5 1 2 N VAL C 427 ? N VAL A 720 O ARG C 435 ? O ARG A 728 
AA6 1 2 N ALA F 4   ? N ALA D 297 O VAL F 39  ? O VAL D 332 
AA6 2 3 O HIS F 40  ? O HIS D 333 N ALA F 33  ? N ALA D 326 
AA6 3 4 O ALA F 34  ? O ALA D 327 N PHE F 13  ? N PHE D 306 
AA7 1 2 N ARG F 157 ? N ARG D 450 O ILE F 306 ? O ILE D 599 
AA8 1 2 N ARG F 270 ? N ARG D 563 O SER F 284 ? O SER D 577 
AA9 1 2 N ARG F 485 ? N ARG D 778 O GLU F 497 ? O GLU D 790 
AA9 2 3 O LEU F 496 ? O LEU D 789 N VAL F 314 ? N VAL D 607 
AA9 3 4 N LEU F 313 ? N LEU D 606 O GLY F 531 ? O GLY D 824 
AB1 1 2 N VAL F 427 ? N VAL D 720 O ARG F 435 ? O ARG D 728 
# 
_pdbx_entry_details.entry_id                   8XK9 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 "C1'" B DG  108 ? ? "O4'" B DG  108 ? ? "C4'" B DG  108 ? ? 104.03 110.10 -6.07 1.00 N 
2  1 "O4'" B DG  108 ? ? "C1'" B DG  108 ? ? N9    B DG  108 ? ? 110.97 108.30 2.67  0.30 N 
3  1 "O4'" B DC  109 ? ? "C1'" B DC  109 ? ? N1    B DC  109 ? ? 111.48 108.30 3.18  0.30 N 
4  1 "C3'" B DC  111 ? ? "O3'" B DC  111 ? ? P     B DOC 112 ? ? 111.97 119.70 -7.73 1.20 Y 
5  1 "O3'" B DC  111 ? ? P     B DOC 112 ? ? OP2   B DOC 112 ? ? 119.44 110.50 8.94  1.10 Y 
6  1 "O4'" C DA  203 ? ? "C1'" C DA  203 ? ? N9    C DA  203 ? ? 110.78 108.30 2.48  0.30 N 
7  1 "C3'" C DC  207 ? ? "O3'" C DC  207 ? ? P     C DG  208 ? ? 112.34 119.70 -7.36 1.20 Y 
8  1 "C3'" C DC  216 ? ? "O3'" C DC  216 ? ? P     C OMG 217 ? ? 110.61 119.70 -9.09 1.20 Y 
9  1 NE    A ARG 457 ? ? CZ    A ARG 457 ? ? NH1   A ARG 457 ? ? 123.44 120.30 3.14  0.50 N 
10 1 "C1'" E DG  108 ? ? "O4'" E DG  108 ? ? "C4'" E DG  108 ? ? 103.99 110.10 -6.11 1.00 N 
11 1 "O4'" E DG  108 ? ? "C1'" E DG  108 ? ? N9    E DG  108 ? ? 111.14 108.30 2.84  0.30 N 
12 1 "O4'" E DC  109 ? ? "C1'" E DC  109 ? ? N1    E DC  109 ? ? 111.30 108.30 3.00  0.30 N 
13 1 "O4'" F DA  203 ? ? "C1'" F DA  203 ? ? N9    F DA  203 ? ? 110.70 108.30 2.40  0.30 N 
14 1 "C3'" F DC  207 ? ? "O3'" F DC  207 ? ? P     F DG  208 ? ? 112.40 119.70 -7.30 1.20 Y 
15 1 "C3'" F DC  216 ? ? "O3'" F DC  216 ? ? P     F OMG 217 ? ? 110.77 119.70 -8.93 1.20 Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 381 ? ? -163.61 110.70 
2  1 PRO A 382 ? ? -69.03  1.88   
3  1 VAL A 433 ? ? -124.60 -61.94 
4  1 TYR A 545 ? ? -122.23 -57.40 
5  1 VAL A 586 ? ? -149.56 -24.60 
6  1 GLN A 613 ? ? 37.31   44.04  
7  1 HIS A 784 ? ? 72.98   -80.82 
8  1 ASP D 381 ? ? -164.30 110.54 
9  1 PRO D 382 ? ? -69.38  1.50   
10 1 VAL D 433 ? ? -125.14 -61.76 
11 1 TYR D 545 ? ? -123.18 -57.09 
12 1 VAL D 586 ? ? -164.26 -6.53  
13 1 GLN D 613 ? ? 38.67   44.57  
14 1 HIS D 784 ? ? 73.66   -81.21 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1  1 ARG A 328 ? ? 0.257 'SIDE CHAIN' 
2  1 ARG A 392 ? ? 0.077 'SIDE CHAIN' 
3  1 ARG A 393 ? ? 0.234 'SIDE CHAIN' 
4  1 ARG A 411 ? ? 0.158 'SIDE CHAIN' 
5  1 ARG A 419 ? ? 0.077 'SIDE CHAIN' 
6  1 ARG A 431 ? ? 0.151 'SIDE CHAIN' 
7  1 ARG A 457 ? ? 0.171 'SIDE CHAIN' 
8  1 ARG A 487 ? ? 0.118 'SIDE CHAIN' 
9  1 ARG A 492 ? ? 0.149 'SIDE CHAIN' 
10 1 ARG A 523 ? ? 0.110 'SIDE CHAIN' 
11 1 ARG A 556 ? ? 0.172 'SIDE CHAIN' 
12 1 ARG A 573 ? ? 0.214 'SIDE CHAIN' 
13 1 ARG A 587 ? ? 0.150 'SIDE CHAIN' 
14 1 ARG A 636 ? ? 0.142 'SIDE CHAIN' 
15 1 ARG A 651 ? ? 0.182 'SIDE CHAIN' 
16 1 ARG A 677 ? ? 0.166 'SIDE CHAIN' 
17 1 ARG A 716 ? ? 0.129 'SIDE CHAIN' 
18 1 ARG D 328 ? ? 0.228 'SIDE CHAIN' 
19 1 ARG D 393 ? ? 0.239 'SIDE CHAIN' 
20 1 ARG D 411 ? ? 0.144 'SIDE CHAIN' 
21 1 ARG D 431 ? ? 0.152 'SIDE CHAIN' 
22 1 ARG D 457 ? ? 0.145 'SIDE CHAIN' 
23 1 ARG D 487 ? ? 0.114 'SIDE CHAIN' 
24 1 ARG D 492 ? ? 0.136 'SIDE CHAIN' 
25 1 ARG D 523 ? ? 0.114 'SIDE CHAIN' 
26 1 ARG D 556 ? ? 0.107 'SIDE CHAIN' 
27 1 ARG D 573 ? ? 0.230 'SIDE CHAIN' 
28 1 ARG D 596 ? ? 0.100 'SIDE CHAIN' 
29 1 ARG D 651 ? ? 0.166 'SIDE CHAIN' 
30 1 ARG D 660 ? ? 0.112 'SIDE CHAIN' 
31 1 ARG D 677 ? ? 0.167 'SIDE CHAIN' 
32 1 ARG D 716 ? ? 0.113 'SIDE CHAIN' 
33 1 ARG D 717 ? ? 0.082 'SIDE CHAIN' 
34 1 ARG D 771 ? ? 0.089 'SIDE CHAIN' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A MET 294 ? C MET 1 
2 1 Y 1 A GLU 295 ? C GLU 2 
3 1 Y 1 D MET 294 ? F MET 1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1LWE O36    O  N N 1   
A1LWE C36    C  N N 2   
A1LWE N31    N  N N 3   
A1LWE C32    C  N N 4   
A1LWE N32    N  N N 5   
A1LWE N33    N  N N 6   
A1LWE C35    C  Y N 7   
A1LWE C34    C  Y N 8   
A1LWE N37    N  Y N 9   
A1LWE C38    C  Y N 10  
A1LWE N39    N  Y N 11  
A1LWE C41    C  N R 12  
A1LWE O44    O  N N 13  
A1LWE C42    C  N R 14  
A1LWE C46    C  N N 15  
A1LWE O42    O  N N 16  
A1LWE C43    C  N R 17  
A1LWE O43    O  N N 18  
A1LWE C44    C  N R 19  
A1LWE C45    C  N N 20  
A1LWE O45    O  N N 21  
A1LWE PA     P  N N 22  
A1LWE O1A    O  N N 23  
A1LWE O2A    O  N N 24  
A1LWE O1B    O  N N 25  
A1LWE PB     P  N N 26  
A1LWE O2B    O  N N 27  
A1LWE O3B    O  N N 28  
A1LWE O3A    O  N N 29  
A1LWE PG     P  N N 30  
A1LWE O1G    O  N N 31  
A1LWE O2G    O  N N 32  
A1LWE O25    O  N N 33  
A1LWE H1     H  N N 34  
A1LWE H2     H  N N 35  
A1LWE H3     H  N N 36  
A1LWE H4     H  N N 37  
A1LWE H5     H  N N 38  
A1LWE H6     H  N N 39  
A1LWE H7     H  N N 40  
A1LWE H8     H  N N 41  
A1LWE H9     H  N N 42  
A1LWE H10    H  N N 43  
A1LWE H11    H  N N 44  
A1LWE H12    H  N N 45  
A1LWE H13    H  N N 46  
A1LWE H14    H  N N 47  
A1LWE H15    H  N N 48  
A1LWE H16    H  N N 49  
A1LWE H17    H  N N 50  
A1LWE H18    H  N N 51  
ALA   N      N  N N 52  
ALA   CA     C  N S 53  
ALA   C      C  N N 54  
ALA   O      O  N N 55  
ALA   CB     C  N N 56  
ALA   OXT    O  N N 57  
ALA   H      H  N N 58  
ALA   H2     H  N N 59  
ALA   HA     H  N N 60  
ALA   HB1    H  N N 61  
ALA   HB2    H  N N 62  
ALA   HB3    H  N N 63  
ALA   HXT    H  N N 64  
ARG   N      N  N N 65  
ARG   CA     C  N S 66  
ARG   C      C  N N 67  
ARG   O      O  N N 68  
ARG   CB     C  N N 69  
ARG   CG     C  N N 70  
ARG   CD     C  N N 71  
ARG   NE     N  N N 72  
ARG   CZ     C  N N 73  
ARG   NH1    N  N N 74  
ARG   NH2    N  N N 75  
ARG   OXT    O  N N 76  
ARG   H      H  N N 77  
ARG   H2     H  N N 78  
ARG   HA     H  N N 79  
ARG   HB2    H  N N 80  
ARG   HB3    H  N N 81  
ARG   HG2    H  N N 82  
ARG   HG3    H  N N 83  
ARG   HD2    H  N N 84  
ARG   HD3    H  N N 85  
ARG   HE     H  N N 86  
ARG   HH11   H  N N 87  
ARG   HH12   H  N N 88  
ARG   HH21   H  N N 89  
ARG   HH22   H  N N 90  
ARG   HXT    H  N N 91  
ASN   N      N  N N 92  
ASN   CA     C  N S 93  
ASN   C      C  N N 94  
ASN   O      O  N N 95  
ASN   CB     C  N N 96  
ASN   CG     C  N N 97  
ASN   OD1    O  N N 98  
ASN   ND2    N  N N 99  
ASN   OXT    O  N N 100 
ASN   H      H  N N 101 
ASN   H2     H  N N 102 
ASN   HA     H  N N 103 
ASN   HB2    H  N N 104 
ASN   HB3    H  N N 105 
ASN   HD21   H  N N 106 
ASN   HD22   H  N N 107 
ASN   HXT    H  N N 108 
ASP   N      N  N N 109 
ASP   CA     C  N S 110 
ASP   C      C  N N 111 
ASP   O      O  N N 112 
ASP   CB     C  N N 113 
ASP   CG     C  N N 114 
ASP   OD1    O  N N 115 
ASP   OD2    O  N N 116 
ASP   OXT    O  N N 117 
ASP   H      H  N N 118 
ASP   H2     H  N N 119 
ASP   HA     H  N N 120 
ASP   HB2    H  N N 121 
ASP   HB3    H  N N 122 
ASP   HD2    H  N N 123 
ASP   HXT    H  N N 124 
DA    OP3    O  N N 125 
DA    P      P  N N 126 
DA    OP1    O  N N 127 
DA    OP2    O  N N 128 
DA    "O5'"  O  N N 129 
DA    "C5'"  C  N N 130 
DA    "C4'"  C  N R 131 
DA    "O4'"  O  N N 132 
DA    "C3'"  C  N S 133 
DA    "O3'"  O  N N 134 
DA    "C2'"  C  N N 135 
DA    "C1'"  C  N R 136 
DA    N9     N  Y N 137 
DA    C8     C  Y N 138 
DA    N7     N  Y N 139 
DA    C5     C  Y N 140 
DA    C6     C  Y N 141 
DA    N6     N  N N 142 
DA    N1     N  Y N 143 
DA    C2     C  Y N 144 
DA    N3     N  Y N 145 
DA    C4     C  Y N 146 
DA    HOP3   H  N N 147 
DA    HOP2   H  N N 148 
DA    "H5'"  H  N N 149 
DA    "H5''" H  N N 150 
DA    "H4'"  H  N N 151 
DA    "H3'"  H  N N 152 
DA    "HO3'" H  N N 153 
DA    "H2'"  H  N N 154 
DA    "H2''" H  N N 155 
DA    "H1'"  H  N N 156 
DA    H8     H  N N 157 
DA    H61    H  N N 158 
DA    H62    H  N N 159 
DA    H2     H  N N 160 
DC    OP3    O  N N 161 
DC    P      P  N N 162 
DC    OP1    O  N N 163 
DC    OP2    O  N N 164 
DC    "O5'"  O  N N 165 
DC    "C5'"  C  N N 166 
DC    "C4'"  C  N R 167 
DC    "O4'"  O  N N 168 
DC    "C3'"  C  N S 169 
DC    "O3'"  O  N N 170 
DC    "C2'"  C  N N 171 
DC    "C1'"  C  N R 172 
DC    N1     N  N N 173 
DC    C2     C  N N 174 
DC    O2     O  N N 175 
DC    N3     N  N N 176 
DC    C4     C  N N 177 
DC    N4     N  N N 178 
DC    C5     C  N N 179 
DC    C6     C  N N 180 
DC    HOP3   H  N N 181 
DC    HOP2   H  N N 182 
DC    "H5'"  H  N N 183 
DC    "H5''" H  N N 184 
DC    "H4'"  H  N N 185 
DC    "H3'"  H  N N 186 
DC    "HO3'" H  N N 187 
DC    "H2'"  H  N N 188 
DC    "H2''" H  N N 189 
DC    "H1'"  H  N N 190 
DC    H41    H  N N 191 
DC    H42    H  N N 192 
DC    H5     H  N N 193 
DC    H6     H  N N 194 
DG    OP3    O  N N 195 
DG    P      P  N N 196 
DG    OP1    O  N N 197 
DG    OP2    O  N N 198 
DG    "O5'"  O  N N 199 
DG    "C5'"  C  N N 200 
DG    "C4'"  C  N R 201 
DG    "O4'"  O  N N 202 
DG    "C3'"  C  N S 203 
DG    "O3'"  O  N N 204 
DG    "C2'"  C  N N 205 
DG    "C1'"  C  N R 206 
DG    N9     N  Y N 207 
DG    C8     C  Y N 208 
DG    N7     N  Y N 209 
DG    C5     C  Y N 210 
DG    C6     C  N N 211 
DG    O6     O  N N 212 
DG    N1     N  N N 213 
DG    C2     C  N N 214 
DG    N2     N  N N 215 
DG    N3     N  N N 216 
DG    C4     C  Y N 217 
DG    HOP3   H  N N 218 
DG    HOP2   H  N N 219 
DG    "H5'"  H  N N 220 
DG    "H5''" H  N N 221 
DG    "H4'"  H  N N 222 
DG    "H3'"  H  N N 223 
DG    "HO3'" H  N N 224 
DG    "H2'"  H  N N 225 
DG    "H2''" H  N N 226 
DG    "H1'"  H  N N 227 
DG    H8     H  N N 228 
DG    H1     H  N N 229 
DG    H21    H  N N 230 
DG    H22    H  N N 231 
DOC   N1     N  N N 232 
DOC   C2     C  N N 233 
DOC   N3     N  N N 234 
DOC   C4     C  N N 235 
DOC   C5     C  N N 236 
DOC   C6     C  N N 237 
DOC   O2     O  N N 238 
DOC   N4     N  N N 239 
DOC   "C1'"  C  N R 240 
DOC   "C2'"  C  N N 241 
DOC   "C3'"  C  N N 242 
DOC   "C4'"  C  N S 243 
DOC   "O4'"  O  N N 244 
DOC   "C5'"  C  N N 245 
DOC   "O5'"  O  N N 246 
DOC   P      P  N N 247 
DOC   OP1    O  N N 248 
DOC   OP2    O  N N 249 
DOC   OP3    O  N N 250 
DOC   H5     H  N N 251 
DOC   H6     H  N N 252 
DOC   HN41   H  N N 253 
DOC   HN42   H  N N 254 
DOC   "H1'"  H  N N 255 
DOC   "H2'"  H  N N 256 
DOC   "H2''" H  N N 257 
DOC   "H3'1" H  N N 258 
DOC   "H3'2" H  N N 259 
DOC   "H4'"  H  N N 260 
DOC   "H5'"  H  N N 261 
DOC   "H5''" H  N N 262 
DOC   HOP2   H  N N 263 
DOC   HOP3   H  N N 264 
DT    OP3    O  N N 265 
DT    P      P  N N 266 
DT    OP1    O  N N 267 
DT    OP2    O  N N 268 
DT    "O5'"  O  N N 269 
DT    "C5'"  C  N N 270 
DT    "C4'"  C  N R 271 
DT    "O4'"  O  N N 272 
DT    "C3'"  C  N S 273 
DT    "O3'"  O  N N 274 
DT    "C2'"  C  N N 275 
DT    "C1'"  C  N R 276 
DT    N1     N  N N 277 
DT    C2     C  N N 278 
DT    O2     O  N N 279 
DT    N3     N  N N 280 
DT    C4     C  N N 281 
DT    O4     O  N N 282 
DT    C5     C  N N 283 
DT    C7     C  N N 284 
DT    C6     C  N N 285 
DT    HOP3   H  N N 286 
DT    HOP2   H  N N 287 
DT    "H5'"  H  N N 288 
DT    "H5''" H  N N 289 
DT    "H4'"  H  N N 290 
DT    "H3'"  H  N N 291 
DT    "HO3'" H  N N 292 
DT    "H2'"  H  N N 293 
DT    "H2''" H  N N 294 
DT    "H1'"  H  N N 295 
DT    H3     H  N N 296 
DT    H71    H  N N 297 
DT    H72    H  N N 298 
DT    H73    H  N N 299 
DT    H6     H  N N 300 
GLN   N      N  N N 301 
GLN   CA     C  N S 302 
GLN   C      C  N N 303 
GLN   O      O  N N 304 
GLN   CB     C  N N 305 
GLN   CG     C  N N 306 
GLN   CD     C  N N 307 
GLN   OE1    O  N N 308 
GLN   NE2    N  N N 309 
GLN   OXT    O  N N 310 
GLN   H      H  N N 311 
GLN   H2     H  N N 312 
GLN   HA     H  N N 313 
GLN   HB2    H  N N 314 
GLN   HB3    H  N N 315 
GLN   HG2    H  N N 316 
GLN   HG3    H  N N 317 
GLN   HE21   H  N N 318 
GLN   HE22   H  N N 319 
GLN   HXT    H  N N 320 
GLU   N      N  N N 321 
GLU   CA     C  N S 322 
GLU   C      C  N N 323 
GLU   O      O  N N 324 
GLU   CB     C  N N 325 
GLU   CG     C  N N 326 
GLU   CD     C  N N 327 
GLU   OE1    O  N N 328 
GLU   OE2    O  N N 329 
GLU   OXT    O  N N 330 
GLU   H      H  N N 331 
GLU   H2     H  N N 332 
GLU   HA     H  N N 333 
GLU   HB2    H  N N 334 
GLU   HB3    H  N N 335 
GLU   HG2    H  N N 336 
GLU   HG3    H  N N 337 
GLU   HE2    H  N N 338 
GLU   HXT    H  N N 339 
GLY   N      N  N N 340 
GLY   CA     C  N N 341 
GLY   C      C  N N 342 
GLY   O      O  N N 343 
GLY   OXT    O  N N 344 
GLY   H      H  N N 345 
GLY   H2     H  N N 346 
GLY   HA2    H  N N 347 
GLY   HA3    H  N N 348 
GLY   HXT    H  N N 349 
HIS   N      N  N N 350 
HIS   CA     C  N S 351 
HIS   C      C  N N 352 
HIS   O      O  N N 353 
HIS   CB     C  N N 354 
HIS   CG     C  Y N 355 
HIS   ND1    N  Y N 356 
HIS   CD2    C  Y N 357 
HIS   CE1    C  Y N 358 
HIS   NE2    N  Y N 359 
HIS   OXT    O  N N 360 
HIS   H      H  N N 361 
HIS   H2     H  N N 362 
HIS   HA     H  N N 363 
HIS   HB2    H  N N 364 
HIS   HB3    H  N N 365 
HIS   HD1    H  N N 366 
HIS   HD2    H  N N 367 
HIS   HE1    H  N N 368 
HIS   HE2    H  N N 369 
HIS   HXT    H  N N 370 
HOH   O      O  N N 371 
HOH   H1     H  N N 372 
HOH   H2     H  N N 373 
ILE   N      N  N N 374 
ILE   CA     C  N S 375 
ILE   C      C  N N 376 
ILE   O      O  N N 377 
ILE   CB     C  N S 378 
ILE   CG1    C  N N 379 
ILE   CG2    C  N N 380 
ILE   CD1    C  N N 381 
ILE   OXT    O  N N 382 
ILE   H      H  N N 383 
ILE   H2     H  N N 384 
ILE   HA     H  N N 385 
ILE   HB     H  N N 386 
ILE   HG12   H  N N 387 
ILE   HG13   H  N N 388 
ILE   HG21   H  N N 389 
ILE   HG22   H  N N 390 
ILE   HG23   H  N N 391 
ILE   HD11   H  N N 392 
ILE   HD12   H  N N 393 
ILE   HD13   H  N N 394 
ILE   HXT    H  N N 395 
LEU   N      N  N N 396 
LEU   CA     C  N S 397 
LEU   C      C  N N 398 
LEU   O      O  N N 399 
LEU   CB     C  N N 400 
LEU   CG     C  N N 401 
LEU   CD1    C  N N 402 
LEU   CD2    C  N N 403 
LEU   OXT    O  N N 404 
LEU   H      H  N N 405 
LEU   H2     H  N N 406 
LEU   HA     H  N N 407 
LEU   HB2    H  N N 408 
LEU   HB3    H  N N 409 
LEU   HG     H  N N 410 
LEU   HD11   H  N N 411 
LEU   HD12   H  N N 412 
LEU   HD13   H  N N 413 
LEU   HD21   H  N N 414 
LEU   HD22   H  N N 415 
LEU   HD23   H  N N 416 
LEU   HXT    H  N N 417 
LYS   N      N  N N 418 
LYS   CA     C  N S 419 
LYS   C      C  N N 420 
LYS   O      O  N N 421 
LYS   CB     C  N N 422 
LYS   CG     C  N N 423 
LYS   CD     C  N N 424 
LYS   CE     C  N N 425 
LYS   NZ     N  N N 426 
LYS   OXT    O  N N 427 
LYS   H      H  N N 428 
LYS   H2     H  N N 429 
LYS   HA     H  N N 430 
LYS   HB2    H  N N 431 
LYS   HB3    H  N N 432 
LYS   HG2    H  N N 433 
LYS   HG3    H  N N 434 
LYS   HD2    H  N N 435 
LYS   HD3    H  N N 436 
LYS   HE2    H  N N 437 
LYS   HE3    H  N N 438 
LYS   HZ1    H  N N 439 
LYS   HZ2    H  N N 440 
LYS   HZ3    H  N N 441 
LYS   HXT    H  N N 442 
MET   N      N  N N 443 
MET   CA     C  N S 444 
MET   C      C  N N 445 
MET   O      O  N N 446 
MET   CB     C  N N 447 
MET   CG     C  N N 448 
MET   SD     S  N N 449 
MET   CE     C  N N 450 
MET   OXT    O  N N 451 
MET   H      H  N N 452 
MET   H2     H  N N 453 
MET   HA     H  N N 454 
MET   HB2    H  N N 455 
MET   HB3    H  N N 456 
MET   HG2    H  N N 457 
MET   HG3    H  N N 458 
MET   HE1    H  N N 459 
MET   HE2    H  N N 460 
MET   HE3    H  N N 461 
MET   HXT    H  N N 462 
MG    MG     MG N N 463 
OMG   P      P  N N 464 
OMG   OP1    O  N N 465 
OMG   OP2    O  N N 466 
OMG   OP3    O  N N 467 
OMG   "O5'"  O  N N 468 
OMG   "C5'"  C  N N 469 
OMG   "C4'"  C  N R 470 
OMG   "O4'"  O  N N 471 
OMG   "C3'"  C  N R 472 
OMG   "O3'"  O  N N 473 
OMG   "C2'"  C  N R 474 
OMG   "O2'"  O  N N 475 
OMG   CM2    C  N N 476 
OMG   "C1'"  C  N R 477 
OMG   N9     N  Y N 478 
OMG   C8     C  Y N 479 
OMG   N7     N  Y N 480 
OMG   C5     C  Y N 481 
OMG   C6     C  N N 482 
OMG   O6     O  N N 483 
OMG   N1     N  N N 484 
OMG   C2     C  N N 485 
OMG   N2     N  N N 486 
OMG   N3     N  N N 487 
OMG   C4     C  Y N 488 
OMG   HOP2   H  N N 489 
OMG   HOP3   H  N N 490 
OMG   "H5'"  H  N N 491 
OMG   "H5''" H  N N 492 
OMG   "H4'"  H  N N 493 
OMG   "H3'"  H  N N 494 
OMG   "HO3'" H  N N 495 
OMG   "H2'"  H  N N 496 
OMG   HM21   H  N N 497 
OMG   HM22   H  N N 498 
OMG   HM23   H  N N 499 
OMG   "H1'"  H  N N 500 
OMG   H8     H  N N 501 
OMG   HN1    H  N N 502 
OMG   HN21   H  N N 503 
OMG   HN22   H  N N 504 
PEG   C1     C  N N 505 
PEG   O1     O  N N 506 
PEG   C2     C  N N 507 
PEG   O2     O  N N 508 
PEG   C3     C  N N 509 
PEG   C4     C  N N 510 
PEG   O4     O  N N 511 
PEG   H11    H  N N 512 
PEG   H12    H  N N 513 
PEG   HO1    H  N N 514 
PEG   H21    H  N N 515 
PEG   H22    H  N N 516 
PEG   H31    H  N N 517 
PEG   H32    H  N N 518 
PEG   H41    H  N N 519 
PEG   H42    H  N N 520 
PEG   HO4    H  N N 521 
PHE   N      N  N N 522 
PHE   CA     C  N S 523 
PHE   C      C  N N 524 
PHE   O      O  N N 525 
PHE   CB     C  N N 526 
PHE   CG     C  Y N 527 
PHE   CD1    C  Y N 528 
PHE   CD2    C  Y N 529 
PHE   CE1    C  Y N 530 
PHE   CE2    C  Y N 531 
PHE   CZ     C  Y N 532 
PHE   OXT    O  N N 533 
PHE   H      H  N N 534 
PHE   H2     H  N N 535 
PHE   HA     H  N N 536 
PHE   HB2    H  N N 537 
PHE   HB3    H  N N 538 
PHE   HD1    H  N N 539 
PHE   HD2    H  N N 540 
PHE   HE1    H  N N 541 
PHE   HE2    H  N N 542 
PHE   HZ     H  N N 543 
PHE   HXT    H  N N 544 
PO4   P      P  N N 545 
PO4   O1     O  N N 546 
PO4   O2     O  N N 547 
PO4   O3     O  N N 548 
PO4   O4     O  N N 549 
PRO   N      N  N N 550 
PRO   CA     C  N S 551 
PRO   C      C  N N 552 
PRO   O      O  N N 553 
PRO   CB     C  N N 554 
PRO   CG     C  N N 555 
PRO   CD     C  N N 556 
PRO   OXT    O  N N 557 
PRO   H      H  N N 558 
PRO   HA     H  N N 559 
PRO   HB2    H  N N 560 
PRO   HB3    H  N N 561 
PRO   HG2    H  N N 562 
PRO   HG3    H  N N 563 
PRO   HD2    H  N N 564 
PRO   HD3    H  N N 565 
PRO   HXT    H  N N 566 
SER   N      N  N N 567 
SER   CA     C  N S 568 
SER   C      C  N N 569 
SER   O      O  N N 570 
SER   CB     C  N N 571 
SER   OG     O  N N 572 
SER   OXT    O  N N 573 
SER   H      H  N N 574 
SER   H2     H  N N 575 
SER   HA     H  N N 576 
SER   HB2    H  N N 577 
SER   HB3    H  N N 578 
SER   HG     H  N N 579 
SER   HXT    H  N N 580 
THR   N      N  N N 581 
THR   CA     C  N S 582 
THR   C      C  N N 583 
THR   O      O  N N 584 
THR   CB     C  N R 585 
THR   OG1    O  N N 586 
THR   CG2    C  N N 587 
THR   OXT    O  N N 588 
THR   H      H  N N 589 
THR   H2     H  N N 590 
THR   HA     H  N N 591 
THR   HB     H  N N 592 
THR   HG1    H  N N 593 
THR   HG21   H  N N 594 
THR   HG22   H  N N 595 
THR   HG23   H  N N 596 
THR   HXT    H  N N 597 
TRP   N      N  N N 598 
TRP   CA     C  N S 599 
TRP   C      C  N N 600 
TRP   O      O  N N 601 
TRP   CB     C  N N 602 
TRP   CG     C  Y N 603 
TRP   CD1    C  Y N 604 
TRP   CD2    C  Y N 605 
TRP   NE1    N  Y N 606 
TRP   CE2    C  Y N 607 
TRP   CE3    C  Y N 608 
TRP   CZ2    C  Y N 609 
TRP   CZ3    C  Y N 610 
TRP   CH2    C  Y N 611 
TRP   OXT    O  N N 612 
TRP   H      H  N N 613 
TRP   H2     H  N N 614 
TRP   HA     H  N N 615 
TRP   HB2    H  N N 616 
TRP   HB3    H  N N 617 
TRP   HD1    H  N N 618 
TRP   HE1    H  N N 619 
TRP   HE3    H  N N 620 
TRP   HZ2    H  N N 621 
TRP   HZ3    H  N N 622 
TRP   HH2    H  N N 623 
TRP   HXT    H  N N 624 
TYR   N      N  N N 625 
TYR   CA     C  N S 626 
TYR   C      C  N N 627 
TYR   O      O  N N 628 
TYR   CB     C  N N 629 
TYR   CG     C  Y N 630 
TYR   CD1    C  Y N 631 
TYR   CD2    C  Y N 632 
TYR   CE1    C  Y N 633 
TYR   CE2    C  Y N 634 
TYR   CZ     C  Y N 635 
TYR   OH     O  N N 636 
TYR   OXT    O  N N 637 
TYR   H      H  N N 638 
TYR   H2     H  N N 639 
TYR   HA     H  N N 640 
TYR   HB2    H  N N 641 
TYR   HB3    H  N N 642 
TYR   HD1    H  N N 643 
TYR   HD2    H  N N 644 
TYR   HE1    H  N N 645 
TYR   HE2    H  N N 646 
TYR   HH     H  N N 647 
TYR   HXT    H  N N 648 
VAL   N      N  N N 649 
VAL   CA     C  N S 650 
VAL   C      C  N N 651 
VAL   O      O  N N 652 
VAL   CB     C  N N 653 
VAL   CG1    C  N N 654 
VAL   CG2    C  N N 655 
VAL   OXT    O  N N 656 
VAL   H      H  N N 657 
VAL   H2     H  N N 658 
VAL   HA     H  N N 659 
VAL   HB     H  N N 660 
VAL   HG11   H  N N 661 
VAL   HG12   H  N N 662 
VAL   HG13   H  N N 663 
VAL   HG21   H  N N 664 
VAL   HG22   H  N N 665 
VAL   HG23   H  N N 666 
VAL   HXT    H  N N 667 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1LWE C46   O42    sing N N 1   
A1LWE O42   C42    sing N N 2   
A1LWE C44   O44    sing N N 3   
A1LWE C44   C45    sing N N 4   
A1LWE C44   C43    sing N N 5   
A1LWE O43   C43    sing N N 6   
A1LWE C42   C41    sing N N 7   
A1LWE C42   C43    sing N N 8   
A1LWE O44   C41    sing N N 9   
A1LWE C41   N39    sing N N 10  
A1LWE C45   O45    sing N N 11  
A1LWE O3B   PB     doub N N 12  
A1LWE N33   C32    doub N N 13  
A1LWE N33   C34    sing N N 14  
A1LWE N32   C32    sing N N 15  
A1LWE N39   C34    sing Y N 16  
A1LWE N39   C38    sing Y N 17  
A1LWE O45   PA     sing N N 18  
A1LWE O2B   PB     sing N N 19  
A1LWE O2A   PA     doub N N 20  
A1LWE C32   N31    sing N N 21  
A1LWE C34   C35    doub Y N 22  
A1LWE PB    O1B    sing N N 23  
A1LWE PB    O3A    sing N N 24  
A1LWE PA    O1B    sing N N 25  
A1LWE PA    O1A    sing N N 26  
A1LWE C38   N37    doub Y N 27  
A1LWE O2G   PG     doub N N 28  
A1LWE N31   C36    sing N N 29  
A1LWE O25   PG     sing N N 30  
A1LWE O3A   PG     sing N N 31  
A1LWE C35   N37    sing Y N 32  
A1LWE C35   C36    sing N N 33  
A1LWE PG    O1G    sing N N 34  
A1LWE C36   O36    doub N N 35  
A1LWE N31   H1     sing N N 36  
A1LWE N32   H2     sing N N 37  
A1LWE N32   H3     sing N N 38  
A1LWE C38   H4     sing N N 39  
A1LWE C41   H5     sing N N 40  
A1LWE C42   H6     sing N N 41  
A1LWE C46   H7     sing N N 42  
A1LWE C46   H8     sing N N 43  
A1LWE C46   H9     sing N N 44  
A1LWE C43   H10    sing N N 45  
A1LWE O43   H11    sing N N 46  
A1LWE C44   H12    sing N N 47  
A1LWE C45   H13    sing N N 48  
A1LWE C45   H14    sing N N 49  
A1LWE O1A   H15    sing N N 50  
A1LWE O2B   H16    sing N N 51  
A1LWE O1G   H17    sing N N 52  
A1LWE O25   H18    sing N N 53  
ALA   N     CA     sing N N 54  
ALA   N     H      sing N N 55  
ALA   N     H2     sing N N 56  
ALA   CA    C      sing N N 57  
ALA   CA    CB     sing N N 58  
ALA   CA    HA     sing N N 59  
ALA   C     O      doub N N 60  
ALA   C     OXT    sing N N 61  
ALA   CB    HB1    sing N N 62  
ALA   CB    HB2    sing N N 63  
ALA   CB    HB3    sing N N 64  
ALA   OXT   HXT    sing N N 65  
ARG   N     CA     sing N N 66  
ARG   N     H      sing N N 67  
ARG   N     H2     sing N N 68  
ARG   CA    C      sing N N 69  
ARG   CA    CB     sing N N 70  
ARG   CA    HA     sing N N 71  
ARG   C     O      doub N N 72  
ARG   C     OXT    sing N N 73  
ARG   CB    CG     sing N N 74  
ARG   CB    HB2    sing N N 75  
ARG   CB    HB3    sing N N 76  
ARG   CG    CD     sing N N 77  
ARG   CG    HG2    sing N N 78  
ARG   CG    HG3    sing N N 79  
ARG   CD    NE     sing N N 80  
ARG   CD    HD2    sing N N 81  
ARG   CD    HD3    sing N N 82  
ARG   NE    CZ     sing N N 83  
ARG   NE    HE     sing N N 84  
ARG   CZ    NH1    sing N N 85  
ARG   CZ    NH2    doub N N 86  
ARG   NH1   HH11   sing N N 87  
ARG   NH1   HH12   sing N N 88  
ARG   NH2   HH21   sing N N 89  
ARG   NH2   HH22   sing N N 90  
ARG   OXT   HXT    sing N N 91  
ASN   N     CA     sing N N 92  
ASN   N     H      sing N N 93  
ASN   N     H2     sing N N 94  
ASN   CA    C      sing N N 95  
ASN   CA    CB     sing N N 96  
ASN   CA    HA     sing N N 97  
ASN   C     O      doub N N 98  
ASN   C     OXT    sing N N 99  
ASN   CB    CG     sing N N 100 
ASN   CB    HB2    sing N N 101 
ASN   CB    HB3    sing N N 102 
ASN   CG    OD1    doub N N 103 
ASN   CG    ND2    sing N N 104 
ASN   ND2   HD21   sing N N 105 
ASN   ND2   HD22   sing N N 106 
ASN   OXT   HXT    sing N N 107 
ASP   N     CA     sing N N 108 
ASP   N     H      sing N N 109 
ASP   N     H2     sing N N 110 
ASP   CA    C      sing N N 111 
ASP   CA    CB     sing N N 112 
ASP   CA    HA     sing N N 113 
ASP   C     O      doub N N 114 
ASP   C     OXT    sing N N 115 
ASP   CB    CG     sing N N 116 
ASP   CB    HB2    sing N N 117 
ASP   CB    HB3    sing N N 118 
ASP   CG    OD1    doub N N 119 
ASP   CG    OD2    sing N N 120 
ASP   OD2   HD2    sing N N 121 
ASP   OXT   HXT    sing N N 122 
DA    OP3   P      sing N N 123 
DA    OP3   HOP3   sing N N 124 
DA    P     OP1    doub N N 125 
DA    P     OP2    sing N N 126 
DA    P     "O5'"  sing N N 127 
DA    OP2   HOP2   sing N N 128 
DA    "O5'" "C5'"  sing N N 129 
DA    "C5'" "C4'"  sing N N 130 
DA    "C5'" "H5'"  sing N N 131 
DA    "C5'" "H5''" sing N N 132 
DA    "C4'" "O4'"  sing N N 133 
DA    "C4'" "C3'"  sing N N 134 
DA    "C4'" "H4'"  sing N N 135 
DA    "O4'" "C1'"  sing N N 136 
DA    "C3'" "O3'"  sing N N 137 
DA    "C3'" "C2'"  sing N N 138 
DA    "C3'" "H3'"  sing N N 139 
DA    "O3'" "HO3'" sing N N 140 
DA    "C2'" "C1'"  sing N N 141 
DA    "C2'" "H2'"  sing N N 142 
DA    "C2'" "H2''" sing N N 143 
DA    "C1'" N9     sing N N 144 
DA    "C1'" "H1'"  sing N N 145 
DA    N9    C8     sing Y N 146 
DA    N9    C4     sing Y N 147 
DA    C8    N7     doub Y N 148 
DA    C8    H8     sing N N 149 
DA    N7    C5     sing Y N 150 
DA    C5    C6     sing Y N 151 
DA    C5    C4     doub Y N 152 
DA    C6    N6     sing N N 153 
DA    C6    N1     doub Y N 154 
DA    N6    H61    sing N N 155 
DA    N6    H62    sing N N 156 
DA    N1    C2     sing Y N 157 
DA    C2    N3     doub Y N 158 
DA    C2    H2     sing N N 159 
DA    N3    C4     sing Y N 160 
DC    OP3   P      sing N N 161 
DC    OP3   HOP3   sing N N 162 
DC    P     OP1    doub N N 163 
DC    P     OP2    sing N N 164 
DC    P     "O5'"  sing N N 165 
DC    OP2   HOP2   sing N N 166 
DC    "O5'" "C5'"  sing N N 167 
DC    "C5'" "C4'"  sing N N 168 
DC    "C5'" "H5'"  sing N N 169 
DC    "C5'" "H5''" sing N N 170 
DC    "C4'" "O4'"  sing N N 171 
DC    "C4'" "C3'"  sing N N 172 
DC    "C4'" "H4'"  sing N N 173 
DC    "O4'" "C1'"  sing N N 174 
DC    "C3'" "O3'"  sing N N 175 
DC    "C3'" "C2'"  sing N N 176 
DC    "C3'" "H3'"  sing N N 177 
DC    "O3'" "HO3'" sing N N 178 
DC    "C2'" "C1'"  sing N N 179 
DC    "C2'" "H2'"  sing N N 180 
DC    "C2'" "H2''" sing N N 181 
DC    "C1'" N1     sing N N 182 
DC    "C1'" "H1'"  sing N N 183 
DC    N1    C2     sing N N 184 
DC    N1    C6     sing N N 185 
DC    C2    O2     doub N N 186 
DC    C2    N3     sing N N 187 
DC    N3    C4     doub N N 188 
DC    C4    N4     sing N N 189 
DC    C4    C5     sing N N 190 
DC    N4    H41    sing N N 191 
DC    N4    H42    sing N N 192 
DC    C5    C6     doub N N 193 
DC    C5    H5     sing N N 194 
DC    C6    H6     sing N N 195 
DG    OP3   P      sing N N 196 
DG    OP3   HOP3   sing N N 197 
DG    P     OP1    doub N N 198 
DG    P     OP2    sing N N 199 
DG    P     "O5'"  sing N N 200 
DG    OP2   HOP2   sing N N 201 
DG    "O5'" "C5'"  sing N N 202 
DG    "C5'" "C4'"  sing N N 203 
DG    "C5'" "H5'"  sing N N 204 
DG    "C5'" "H5''" sing N N 205 
DG    "C4'" "O4'"  sing N N 206 
DG    "C4'" "C3'"  sing N N 207 
DG    "C4'" "H4'"  sing N N 208 
DG    "O4'" "C1'"  sing N N 209 
DG    "C3'" "O3'"  sing N N 210 
DG    "C3'" "C2'"  sing N N 211 
DG    "C3'" "H3'"  sing N N 212 
DG    "O3'" "HO3'" sing N N 213 
DG    "C2'" "C1'"  sing N N 214 
DG    "C2'" "H2'"  sing N N 215 
DG    "C2'" "H2''" sing N N 216 
DG    "C1'" N9     sing N N 217 
DG    "C1'" "H1'"  sing N N 218 
DG    N9    C8     sing Y N 219 
DG    N9    C4     sing Y N 220 
DG    C8    N7     doub Y N 221 
DG    C8    H8     sing N N 222 
DG    N7    C5     sing Y N 223 
DG    C5    C6     sing N N 224 
DG    C5    C4     doub Y N 225 
DG    C6    O6     doub N N 226 
DG    C6    N1     sing N N 227 
DG    N1    C2     sing N N 228 
DG    N1    H1     sing N N 229 
DG    C2    N2     sing N N 230 
DG    C2    N3     doub N N 231 
DG    N2    H21    sing N N 232 
DG    N2    H22    sing N N 233 
DG    N3    C4     sing N N 234 
DOC   N1    C2     sing N N 235 
DOC   N1    C6     sing N N 236 
DOC   N1    "C1'"  sing N N 237 
DOC   C2    N3     sing N N 238 
DOC   C2    O2     doub N N 239 
DOC   N3    C4     doub N N 240 
DOC   C4    C5     sing N N 241 
DOC   C4    N4     sing N N 242 
DOC   C5    C6     doub N N 243 
DOC   C5    H5     sing N N 244 
DOC   C6    H6     sing N N 245 
DOC   N4    HN41   sing N N 246 
DOC   N4    HN42   sing N N 247 
DOC   "C1'" "C2'"  sing N N 248 
DOC   "C1'" "O4'"  sing N N 249 
DOC   "C1'" "H1'"  sing N N 250 
DOC   "C2'" "C3'"  sing N N 251 
DOC   "C2'" "H2'"  sing N N 252 
DOC   "C2'" "H2''" sing N N 253 
DOC   "C3'" "C4'"  sing N N 254 
DOC   "C3'" "H3'1" sing N N 255 
DOC   "C3'" "H3'2" sing N N 256 
DOC   "C4'" "O4'"  sing N N 257 
DOC   "C4'" "C5'"  sing N N 258 
DOC   "C4'" "H4'"  sing N N 259 
DOC   "C5'" "O5'"  sing N N 260 
DOC   "C5'" "H5'"  sing N N 261 
DOC   "C5'" "H5''" sing N N 262 
DOC   "O5'" P      sing N N 263 
DOC   P     OP1    doub N N 264 
DOC   P     OP2    sing N N 265 
DOC   P     OP3    sing N N 266 
DOC   OP2   HOP2   sing N N 267 
DOC   OP3   HOP3   sing N N 268 
DT    OP3   P      sing N N 269 
DT    OP3   HOP3   sing N N 270 
DT    P     OP1    doub N N 271 
DT    P     OP2    sing N N 272 
DT    P     "O5'"  sing N N 273 
DT    OP2   HOP2   sing N N 274 
DT    "O5'" "C5'"  sing N N 275 
DT    "C5'" "C4'"  sing N N 276 
DT    "C5'" "H5'"  sing N N 277 
DT    "C5'" "H5''" sing N N 278 
DT    "C4'" "O4'"  sing N N 279 
DT    "C4'" "C3'"  sing N N 280 
DT    "C4'" "H4'"  sing N N 281 
DT    "O4'" "C1'"  sing N N 282 
DT    "C3'" "O3'"  sing N N 283 
DT    "C3'" "C2'"  sing N N 284 
DT    "C3'" "H3'"  sing N N 285 
DT    "O3'" "HO3'" sing N N 286 
DT    "C2'" "C1'"  sing N N 287 
DT    "C2'" "H2'"  sing N N 288 
DT    "C2'" "H2''" sing N N 289 
DT    "C1'" N1     sing N N 290 
DT    "C1'" "H1'"  sing N N 291 
DT    N1    C2     sing N N 292 
DT    N1    C6     sing N N 293 
DT    C2    O2     doub N N 294 
DT    C2    N3     sing N N 295 
DT    N3    C4     sing N N 296 
DT    N3    H3     sing N N 297 
DT    C4    O4     doub N N 298 
DT    C4    C5     sing N N 299 
DT    C5    C7     sing N N 300 
DT    C5    C6     doub N N 301 
DT    C7    H71    sing N N 302 
DT    C7    H72    sing N N 303 
DT    C7    H73    sing N N 304 
DT    C6    H6     sing N N 305 
GLN   N     CA     sing N N 306 
GLN   N     H      sing N N 307 
GLN   N     H2     sing N N 308 
GLN   CA    C      sing N N 309 
GLN   CA    CB     sing N N 310 
GLN   CA    HA     sing N N 311 
GLN   C     O      doub N N 312 
GLN   C     OXT    sing N N 313 
GLN   CB    CG     sing N N 314 
GLN   CB    HB2    sing N N 315 
GLN   CB    HB3    sing N N 316 
GLN   CG    CD     sing N N 317 
GLN   CG    HG2    sing N N 318 
GLN   CG    HG3    sing N N 319 
GLN   CD    OE1    doub N N 320 
GLN   CD    NE2    sing N N 321 
GLN   NE2   HE21   sing N N 322 
GLN   NE2   HE22   sing N N 323 
GLN   OXT   HXT    sing N N 324 
GLU   N     CA     sing N N 325 
GLU   N     H      sing N N 326 
GLU   N     H2     sing N N 327 
GLU   CA    C      sing N N 328 
GLU   CA    CB     sing N N 329 
GLU   CA    HA     sing N N 330 
GLU   C     O      doub N N 331 
GLU   C     OXT    sing N N 332 
GLU   CB    CG     sing N N 333 
GLU   CB    HB2    sing N N 334 
GLU   CB    HB3    sing N N 335 
GLU   CG    CD     sing N N 336 
GLU   CG    HG2    sing N N 337 
GLU   CG    HG3    sing N N 338 
GLU   CD    OE1    doub N N 339 
GLU   CD    OE2    sing N N 340 
GLU   OE2   HE2    sing N N 341 
GLU   OXT   HXT    sing N N 342 
GLY   N     CA     sing N N 343 
GLY   N     H      sing N N 344 
GLY   N     H2     sing N N 345 
GLY   CA    C      sing N N 346 
GLY   CA    HA2    sing N N 347 
GLY   CA    HA3    sing N N 348 
GLY   C     O      doub N N 349 
GLY   C     OXT    sing N N 350 
GLY   OXT   HXT    sing N N 351 
HIS   N     CA     sing N N 352 
HIS   N     H      sing N N 353 
HIS   N     H2     sing N N 354 
HIS   CA    C      sing N N 355 
HIS   CA    CB     sing N N 356 
HIS   CA    HA     sing N N 357 
HIS   C     O      doub N N 358 
HIS   C     OXT    sing N N 359 
HIS   CB    CG     sing N N 360 
HIS   CB    HB2    sing N N 361 
HIS   CB    HB3    sing N N 362 
HIS   CG    ND1    sing Y N 363 
HIS   CG    CD2    doub Y N 364 
HIS   ND1   CE1    doub Y N 365 
HIS   ND1   HD1    sing N N 366 
HIS   CD2   NE2    sing Y N 367 
HIS   CD2   HD2    sing N N 368 
HIS   CE1   NE2    sing Y N 369 
HIS   CE1   HE1    sing N N 370 
HIS   NE2   HE2    sing N N 371 
HIS   OXT   HXT    sing N N 372 
HOH   O     H1     sing N N 373 
HOH   O     H2     sing N N 374 
ILE   N     CA     sing N N 375 
ILE   N     H      sing N N 376 
ILE   N     H2     sing N N 377 
ILE   CA    C      sing N N 378 
ILE   CA    CB     sing N N 379 
ILE   CA    HA     sing N N 380 
ILE   C     O      doub N N 381 
ILE   C     OXT    sing N N 382 
ILE   CB    CG1    sing N N 383 
ILE   CB    CG2    sing N N 384 
ILE   CB    HB     sing N N 385 
ILE   CG1   CD1    sing N N 386 
ILE   CG1   HG12   sing N N 387 
ILE   CG1   HG13   sing N N 388 
ILE   CG2   HG21   sing N N 389 
ILE   CG2   HG22   sing N N 390 
ILE   CG2   HG23   sing N N 391 
ILE   CD1   HD11   sing N N 392 
ILE   CD1   HD12   sing N N 393 
ILE   CD1   HD13   sing N N 394 
ILE   OXT   HXT    sing N N 395 
LEU   N     CA     sing N N 396 
LEU   N     H      sing N N 397 
LEU   N     H2     sing N N 398 
LEU   CA    C      sing N N 399 
LEU   CA    CB     sing N N 400 
LEU   CA    HA     sing N N 401 
LEU   C     O      doub N N 402 
LEU   C     OXT    sing N N 403 
LEU   CB    CG     sing N N 404 
LEU   CB    HB2    sing N N 405 
LEU   CB    HB3    sing N N 406 
LEU   CG    CD1    sing N N 407 
LEU   CG    CD2    sing N N 408 
LEU   CG    HG     sing N N 409 
LEU   CD1   HD11   sing N N 410 
LEU   CD1   HD12   sing N N 411 
LEU   CD1   HD13   sing N N 412 
LEU   CD2   HD21   sing N N 413 
LEU   CD2   HD22   sing N N 414 
LEU   CD2   HD23   sing N N 415 
LEU   OXT   HXT    sing N N 416 
LYS   N     CA     sing N N 417 
LYS   N     H      sing N N 418 
LYS   N     H2     sing N N 419 
LYS   CA    C      sing N N 420 
LYS   CA    CB     sing N N 421 
LYS   CA    HA     sing N N 422 
LYS   C     O      doub N N 423 
LYS   C     OXT    sing N N 424 
LYS   CB    CG     sing N N 425 
LYS   CB    HB2    sing N N 426 
LYS   CB    HB3    sing N N 427 
LYS   CG    CD     sing N N 428 
LYS   CG    HG2    sing N N 429 
LYS   CG    HG3    sing N N 430 
LYS   CD    CE     sing N N 431 
LYS   CD    HD2    sing N N 432 
LYS   CD    HD3    sing N N 433 
LYS   CE    NZ     sing N N 434 
LYS   CE    HE2    sing N N 435 
LYS   CE    HE3    sing N N 436 
LYS   NZ    HZ1    sing N N 437 
LYS   NZ    HZ2    sing N N 438 
LYS   NZ    HZ3    sing N N 439 
LYS   OXT   HXT    sing N N 440 
MET   N     CA     sing N N 441 
MET   N     H      sing N N 442 
MET   N     H2     sing N N 443 
MET   CA    C      sing N N 444 
MET   CA    CB     sing N N 445 
MET   CA    HA     sing N N 446 
MET   C     O      doub N N 447 
MET   C     OXT    sing N N 448 
MET   CB    CG     sing N N 449 
MET   CB    HB2    sing N N 450 
MET   CB    HB3    sing N N 451 
MET   CG    SD     sing N N 452 
MET   CG    HG2    sing N N 453 
MET   CG    HG3    sing N N 454 
MET   SD    CE     sing N N 455 
MET   CE    HE1    sing N N 456 
MET   CE    HE2    sing N N 457 
MET   CE    HE3    sing N N 458 
MET   OXT   HXT    sing N N 459 
OMG   P     OP1    doub N N 460 
OMG   P     OP2    sing N N 461 
OMG   P     OP3    sing N N 462 
OMG   P     "O5'"  sing N N 463 
OMG   OP2   HOP2   sing N N 464 
OMG   OP3   HOP3   sing N N 465 
OMG   "O5'" "C5'"  sing N N 466 
OMG   "C5'" "C4'"  sing N N 467 
OMG   "C5'" "H5'"  sing N N 468 
OMG   "C5'" "H5''" sing N N 469 
OMG   "C4'" "O4'"  sing N N 470 
OMG   "C4'" "C3'"  sing N N 471 
OMG   "C4'" "H4'"  sing N N 472 
OMG   "O4'" "C1'"  sing N N 473 
OMG   "C3'" "O3'"  sing N N 474 
OMG   "C3'" "C2'"  sing N N 475 
OMG   "C3'" "H3'"  sing N N 476 
OMG   "O3'" "HO3'" sing N N 477 
OMG   "C2'" "O2'"  sing N N 478 
OMG   "C2'" "C1'"  sing N N 479 
OMG   "C2'" "H2'"  sing N N 480 
OMG   "O2'" CM2    sing N N 481 
OMG   CM2   HM21   sing N N 482 
OMG   CM2   HM22   sing N N 483 
OMG   CM2   HM23   sing N N 484 
OMG   "C1'" N9     sing N N 485 
OMG   "C1'" "H1'"  sing N N 486 
OMG   N9    C8     sing Y N 487 
OMG   N9    C4     sing Y N 488 
OMG   C8    N7     doub Y N 489 
OMG   C8    H8     sing N N 490 
OMG   N7    C5     sing Y N 491 
OMG   C5    C6     sing N N 492 
OMG   C5    C4     doub Y N 493 
OMG   C6    O6     doub N N 494 
OMG   C6    N1     sing N N 495 
OMG   N1    C2     sing N N 496 
OMG   N1    HN1    sing N N 497 
OMG   C2    N2     sing N N 498 
OMG   C2    N3     doub N N 499 
OMG   N2    HN21   sing N N 500 
OMG   N2    HN22   sing N N 501 
OMG   N3    C4     sing N N 502 
PEG   C1    O1     sing N N 503 
PEG   C1    C2     sing N N 504 
PEG   C1    H11    sing N N 505 
PEG   C1    H12    sing N N 506 
PEG   O1    HO1    sing N N 507 
PEG   C2    O2     sing N N 508 
PEG   C2    H21    sing N N 509 
PEG   C2    H22    sing N N 510 
PEG   O2    C3     sing N N 511 
PEG   C3    C4     sing N N 512 
PEG   C3    H31    sing N N 513 
PEG   C3    H32    sing N N 514 
PEG   C4    O4     sing N N 515 
PEG   C4    H41    sing N N 516 
PEG   C4    H42    sing N N 517 
PEG   O4    HO4    sing N N 518 
PHE   N     CA     sing N N 519 
PHE   N     H      sing N N 520 
PHE   N     H2     sing N N 521 
PHE   CA    C      sing N N 522 
PHE   CA    CB     sing N N 523 
PHE   CA    HA     sing N N 524 
PHE   C     O      doub N N 525 
PHE   C     OXT    sing N N 526 
PHE   CB    CG     sing N N 527 
PHE   CB    HB2    sing N N 528 
PHE   CB    HB3    sing N N 529 
PHE   CG    CD1    doub Y N 530 
PHE   CG    CD2    sing Y N 531 
PHE   CD1   CE1    sing Y N 532 
PHE   CD1   HD1    sing N N 533 
PHE   CD2   CE2    doub Y N 534 
PHE   CD2   HD2    sing N N 535 
PHE   CE1   CZ     doub Y N 536 
PHE   CE1   HE1    sing N N 537 
PHE   CE2   CZ     sing Y N 538 
PHE   CE2   HE2    sing N N 539 
PHE   CZ    HZ     sing N N 540 
PHE   OXT   HXT    sing N N 541 
PO4   P     O1     doub N N 542 
PO4   P     O2     sing N N 543 
PO4   P     O3     sing N N 544 
PO4   P     O4     sing N N 545 
PRO   N     CA     sing N N 546 
PRO   N     CD     sing N N 547 
PRO   N     H      sing N N 548 
PRO   CA    C      sing N N 549 
PRO   CA    CB     sing N N 550 
PRO   CA    HA     sing N N 551 
PRO   C     O      doub N N 552 
PRO   C     OXT    sing N N 553 
PRO   CB    CG     sing N N 554 
PRO   CB    HB2    sing N N 555 
PRO   CB    HB3    sing N N 556 
PRO   CG    CD     sing N N 557 
PRO   CG    HG2    sing N N 558 
PRO   CG    HG3    sing N N 559 
PRO   CD    HD2    sing N N 560 
PRO   CD    HD3    sing N N 561 
PRO   OXT   HXT    sing N N 562 
SER   N     CA     sing N N 563 
SER   N     H      sing N N 564 
SER   N     H2     sing N N 565 
SER   CA    C      sing N N 566 
SER   CA    CB     sing N N 567 
SER   CA    HA     sing N N 568 
SER   C     O      doub N N 569 
SER   C     OXT    sing N N 570 
SER   CB    OG     sing N N 571 
SER   CB    HB2    sing N N 572 
SER   CB    HB3    sing N N 573 
SER   OG    HG     sing N N 574 
SER   OXT   HXT    sing N N 575 
THR   N     CA     sing N N 576 
THR   N     H      sing N N 577 
THR   N     H2     sing N N 578 
THR   CA    C      sing N N 579 
THR   CA    CB     sing N N 580 
THR   CA    HA     sing N N 581 
THR   C     O      doub N N 582 
THR   C     OXT    sing N N 583 
THR   CB    OG1    sing N N 584 
THR   CB    CG2    sing N N 585 
THR   CB    HB     sing N N 586 
THR   OG1   HG1    sing N N 587 
THR   CG2   HG21   sing N N 588 
THR   CG2   HG22   sing N N 589 
THR   CG2   HG23   sing N N 590 
THR   OXT   HXT    sing N N 591 
TRP   N     CA     sing N N 592 
TRP   N     H      sing N N 593 
TRP   N     H2     sing N N 594 
TRP   CA    C      sing N N 595 
TRP   CA    CB     sing N N 596 
TRP   CA    HA     sing N N 597 
TRP   C     O      doub N N 598 
TRP   C     OXT    sing N N 599 
TRP   CB    CG     sing N N 600 
TRP   CB    HB2    sing N N 601 
TRP   CB    HB3    sing N N 602 
TRP   CG    CD1    doub Y N 603 
TRP   CG    CD2    sing Y N 604 
TRP   CD1   NE1    sing Y N 605 
TRP   CD1   HD1    sing N N 606 
TRP   CD2   CE2    doub Y N 607 
TRP   CD2   CE3    sing Y N 608 
TRP   NE1   CE2    sing Y N 609 
TRP   NE1   HE1    sing N N 610 
TRP   CE2   CZ2    sing Y N 611 
TRP   CE3   CZ3    doub Y N 612 
TRP   CE3   HE3    sing N N 613 
TRP   CZ2   CH2    doub Y N 614 
TRP   CZ2   HZ2    sing N N 615 
TRP   CZ3   CH2    sing Y N 616 
TRP   CZ3   HZ3    sing N N 617 
TRP   CH2   HH2    sing N N 618 
TRP   OXT   HXT    sing N N 619 
TYR   N     CA     sing N N 620 
TYR   N     H      sing N N 621 
TYR   N     H2     sing N N 622 
TYR   CA    C      sing N N 623 
TYR   CA    CB     sing N N 624 
TYR   CA    HA     sing N N 625 
TYR   C     O      doub N N 626 
TYR   C     OXT    sing N N 627 
TYR   CB    CG     sing N N 628 
TYR   CB    HB2    sing N N 629 
TYR   CB    HB3    sing N N 630 
TYR   CG    CD1    doub Y N 631 
TYR   CG    CD2    sing Y N 632 
TYR   CD1   CE1    sing Y N 633 
TYR   CD1   HD1    sing N N 634 
TYR   CD2   CE2    doub Y N 635 
TYR   CD2   HD2    sing N N 636 
TYR   CE1   CZ     doub Y N 637 
TYR   CE1   HE1    sing N N 638 
TYR   CE2   CZ     sing Y N 639 
TYR   CE2   HE2    sing N N 640 
TYR   CZ    OH     sing N N 641 
TYR   OH    HH     sing N N 642 
TYR   OXT   HXT    sing N N 643 
VAL   N     CA     sing N N 644 
VAL   N     H      sing N N 645 
VAL   N     H2     sing N N 646 
VAL   CA    C      sing N N 647 
VAL   CA    CB     sing N N 648 
VAL   CA    HA     sing N N 649 
VAL   C     O      doub N N 650 
VAL   C     OXT    sing N N 651 
VAL   CB    CG1    sing N N 652 
VAL   CB    CG2    sing N N 653 
VAL   CB    HB     sing N N 654 
VAL   CG1   HG11   sing N N 655 
VAL   CG1   HG12   sing N N 656 
VAL   CG1   HG13   sing N N 657 
VAL   CG2   HG21   sing N N 658 
VAL   CG2   HG22   sing N N 659 
VAL   CG2   HG23   sing N N 660 
VAL   OXT   HXT    sing N N 661 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
8XK9 'double helix'         
8XK9 'a-form double helix'  
8XK9 'b-form double helix'  
8XK9 'mismatched base pair' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 A DG  1  1_555 B DC 15 1_555 -0.384 -0.018 0.000  -9.833  -15.604 -2.114 1  B_DG101:DC216_C  B 101 ? C 216 ? 19 1 
1 A DA  2  1_555 B DT 14 1_555 -0.227 0.105  0.052  -3.146  -7.799  -1.253 2  B_DA102:DT215_C  B 102 ? C 215 ? 20 1 
1 A DC  3  1_555 B DG 13 1_555 0.018  -0.054 0.148  -2.885  -10.970 1.097  3  B_DC103:DG214_C  B 103 ? C 214 ? 19 1 
1 A DC  4  1_555 B DG 12 1_555 0.330  -0.091 -0.043 -1.382  0.477   -0.573 4  B_DC104:DG213_C  B 104 ? C 213 ? 19 1 
1 A DA  5  1_555 B DT 11 1_555 0.170  -0.101 0.378  6.182   -12.310 -5.443 5  B_DA105:DT212_C  B 105 ? C 212 ? 20 1 
1 A DC  6  1_555 B DG 10 1_555 0.234  0.018  0.262  1.046   -12.234 0.876  6  B_DC106:DG211_C  B 106 ? C 211 ? 19 1 
1 A DG  7  1_555 B DC 9  1_555 -0.523 -0.094 0.197  10.613  -12.258 2.542  7  B_DG107:DC210_C  B 107 ? C 210 ? 19 1 
1 A DG  8  1_555 B DC 8  1_555 -0.029 -0.200 -0.179 1.027   -8.040  -3.321 8  B_DG108:DC209_C  B 108 ? C 209 ? 19 1 
1 A DC  9  1_555 B DG 7  1_555 0.119  -0.109 -0.435 10.117  -2.835  -0.647 9  B_DC109:DG208_C  B 109 ? C 208 ? 19 1 
1 A DG  10 1_555 B DC 6  1_555 -0.399 -0.101 -0.079 3.860   -11.707 0.896  10 B_DG110:DC207_C  B 110 ? C 207 ? 19 1 
1 A DC  11 1_555 B DG 5  1_555 0.322  -0.033 -0.067 6.484   -8.457  0.511  11 B_DC111:DG206_C  B 111 ? C 206 ? 19 1 
1 A DOC 12 1_555 B DG 4  1_555 0.055  -0.060 -0.071 5.376   -10.079 1.267  12 B_DOC112:DG205_C B 112 ? C 205 ? 19 1 
1 D DG  1  1_555 E DC 15 1_555 -0.370 -0.050 -0.011 -10.163 -15.610 -3.011 13 E_DG101:DC216_F  E 101 ? F 216 ? 19 1 
1 D DA  2  1_555 E DT 14 1_555 -0.220 0.079  0.046  -3.325  -7.655  -2.049 14 E_DA102:DT215_F  E 102 ? F 215 ? 20 1 
1 D DC  3  1_555 E DG 13 1_555 0.002  -0.047 0.138  -2.854  -11.028 0.475  15 E_DC103:DG214_F  E 103 ? F 214 ? 19 1 
1 D DC  4  1_555 E DG 12 1_555 0.307  -0.100 -0.041 -1.324  0.212   -0.806 16 E_DC104:DG213_F  E 104 ? F 213 ? 19 1 
1 D DA  5  1_555 E DT 11 1_555 0.129  -0.101 0.385  6.115   -12.488 -5.224 17 E_DA105:DT212_F  E 105 ? F 212 ? 20 1 
1 D DC  6  1_555 E DG 10 1_555 0.199  0.055  0.284  1.093   -12.350 1.563  18 E_DC106:DG211_F  E 106 ? F 211 ? 19 1 
1 D DG  7  1_555 E DC 9  1_555 -0.569 -0.070 0.201  10.898  -12.342 2.804  19 E_DG107:DC210_F  E 107 ? F 210 ? 19 1 
1 D DG  8  1_555 E DC 8  1_555 -0.021 -0.200 -0.164 1.609   -7.784  -3.342 20 E_DG108:DC209_F  E 108 ? F 209 ? 19 1 
1 D DC  9  1_555 E DG 7  1_555 0.143  -0.130 -0.419 10.561  -3.273  -0.527 21 E_DC109:DG208_F  E 109 ? F 208 ? 19 1 
1 D DG  10 1_555 E DC 6  1_555 -0.451 -0.133 -0.064 3.618   -11.427 0.619  22 E_DG110:DC207_F  E 110 ? F 207 ? 19 1 
1 D DC  11 1_555 E DG 5  1_555 0.346  -0.034 -0.016 5.818   -7.843  1.290  23 E_DC111:DG206_F  E 111 ? F 206 ? 19 1 
1 D DOC 12 1_555 E DG 4  1_555 0.104  -0.047 -0.034 5.336   -10.877 1.856  24 E_DOC112:DG205_F E 112 ? F 205 ? 19 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 A DG 1  1_555 B DC 15 1_555 A DA  2  1_555 B DT 14 1_555 -0.372 0.235  3.182 -2.808  2.977  35.096 -0.044 0.206  3.210 4.917  
4.637   35.327 1  BB_DG101DA102:DT215DC216_CC  B 101 ? C 216 ? B 102 ? C 215 ? 
1 A DA 2  1_555 B DT 14 1_555 A DC  3  1_555 B DG 13 1_555 0.154  -0.514 3.356 -0.075  0.901  32.299 -1.087 -0.291 3.341 1.619  
0.135   32.311 2  BB_DA102DC103:DG214DT215_CC  B 102 ? C 215 ? B 103 ? C 214 ? 
1 A DC 3  1_555 B DG 13 1_555 A DC  4  1_555 B DG 12 1_555 1.107  0.831  3.349 6.425   4.128  36.309 0.716  -0.822 3.557 6.535  
-10.172 37.077 3  BB_DC103DC104:DG213DG214_CC  B 103 ? C 214 ? B 104 ? C 213 ? 
1 A DC 4  1_555 B DG 12 1_555 A DA  5  1_555 B DT 11 1_555 -1.177 1.238  3.241 -6.822  2.875  36.861 1.533  0.905  3.479 4.491  
10.657  37.571 4  BB_DC104DA105:DT212DG213_CC  B 104 ? C 213 ? B 105 ? C 212 ? 
1 A DA 5  1_555 B DT 11 1_555 A DC  6  1_555 B DG 10 1_555 0.836  -0.764 3.431 0.576   -2.398 32.803 -0.915 -1.372 3.491 -4.238 
-1.018  32.893 5  BB_DA105DC106:DG211DT212_CC  B 105 ? C 212 ? B 106 ? C 211 ? 
1 A DC 6  1_555 B DG 10 1_555 A DG  7  1_555 B DC 9  1_555 -0.102 0.567  3.160 1.732   8.285  31.486 -0.416 0.480  3.192 14.932 
-3.121  32.576 6  BB_DC106DG107:DC210DG211_CC  B 106 ? C 211 ? B 107 ? C 210 ? 
1 A DG 7  1_555 B DC 9  1_555 A DG  8  1_555 B DC 8  1_555 0.577  -0.422 3.510 2.506   3.285  33.976 -1.273 -0.556 3.487 5.596  
-4.268  34.219 7  BB_DG107DG108:DC209DC210_CC  B 107 ? C 210 ? B 108 ? C 209 ? 
1 A DG 8  1_555 B DC 8  1_555 A DC  9  1_555 B DG 7  1_555 0.871  -0.739 3.153 2.913   7.325  29.139 -2.838 -1.109 2.955 14.234 
-5.661  30.164 8  BB_DG108DC109:DG208DC209_CC  B 108 ? C 209 ? B 109 ? C 208 ? 
1 A DC 9  1_555 B DG 7  1_555 A DG  10 1_555 B DC 6  1_555 -0.735 -0.168 3.541 -10.017 8.783  38.283 -1.335 -0.182 3.498 12.924 
14.740  40.452 9  BB_DC109DG110:DC207DG208_CC  B 109 ? C 208 ? B 110 ? C 207 ? 
1 A DG 10 1_555 B DC 6  1_555 A DC  11 1_555 B DG 5  1_555 -0.359 -1.666 3.448 -2.243  10.791 29.638 -5.009 0.256  2.710 20.235 
4.205   31.578 10 BB_DG110DC111:DG206DC207_CC  B 110 ? C 207 ? B 111 ? C 206 ? 
1 A DC 11 1_555 B DG 5  1_555 A DOC 12 1_555 B DG 4  1_555 -0.114 -1.549 3.417 -0.545  5.118  29.521 -4.058 0.108  3.111 9.948  
1.060   29.957 11 BB_DC111DOC112:DG205DG206_CC B 111 ? C 206 ? B 112 ? C 205 ? 
1 D DG 1  1_555 E DC 15 1_555 D DA  2  1_555 E DT 14 1_555 -0.375 0.235  3.179 -2.900  2.984  35.100 -0.044 0.198  3.208 4.927  
4.788   35.338 12 EE_DG101DA102:DT215DC216_FF  E 101 ? F 216 ? E 102 ? F 215 ? 
1 D DA 2  1_555 E DT 14 1_555 D DC  3  1_555 E DG 13 1_555 0.156  -0.503 3.351 -0.021  0.917  32.313 -1.069 -0.284 3.335 1.648  
0.038   32.326 13 EE_DA102DC103:DG214DT215_FF  E 102 ? F 215 ? E 103 ? F 214 ? 
1 D DC 3  1_555 E DG 13 1_555 D DC  4  1_555 E DG 12 1_555 1.107  0.825  3.347 6.361   4.217  36.415 0.696  -0.833 3.554 6.658  
-10.044 37.180 14 EE_DC103DC104:DG213DG214_FF  E 103 ? F 214 ? E 104 ? F 213 ? 
1 D DC 4  1_555 E DG 12 1_555 D DA  5  1_555 E DT 11 1_555 -1.158 1.230  3.239 -6.905  2.949  36.826 1.512  0.865  3.477 4.610  
10.792  37.558 15 EE_DC104DA105:DT212DG213_FF  E 104 ? F 213 ? E 105 ? F 212 ? 
1 D DA 5  1_555 E DT 11 1_555 D DC  6  1_555 E DG 10 1_555 0.854  -0.772 3.429 0.470   -2.445 32.705 -0.923 -1.427 3.487 -4.335 
-0.834  32.797 16 EE_DA105DC106:DG211DT212_FF  E 105 ? F 212 ? E 106 ? F 211 ? 
1 D DC 6  1_555 E DG 10 1_555 D DG  7  1_555 E DC 9  1_555 -0.128 0.558  3.148 1.756   8.606  31.406 -0.482 0.530  3.174 15.522 
-3.167  32.581 17 EE_DC106DG107:DC210DG211_FF  E 106 ? F 211 ? E 107 ? F 210 ? 
1 D DG 7  1_555 E DC 9  1_555 D DG  8  1_555 E DC 8  1_555 0.554  -0.407 3.501 2.309   3.041  34.262 -1.192 -0.552 3.482 5.142  
-3.904  34.467 18 EE_DG107DG108:DC209DC210_FF  E 107 ? F 210 ? E 108 ? F 209 ? 
1 D DG 8  1_555 E DC 8  1_555 D DC  9  1_555 E DG 7  1_555 0.871  -0.742 3.156 2.919   7.298  29.415 -2.804 -1.104 2.961 14.059 
-5.623  30.425 19 EE_DG108DC109:DG208DC209_FF  E 108 ? F 209 ? E 109 ? F 208 ? 
1 D DC 9  1_555 E DG 7  1_555 D DG  10 1_555 E DC 6  1_555 -0.779 -0.172 3.548 -10.432 8.882  38.044 -1.364 -0.181 3.511 13.116 
15.406  40.350 20 EE_DC109DG110:DC207DG208_FF  E 109 ? F 208 ? E 110 ? F 207 ? 
1 D DG 10 1_555 E DC 6  1_555 D DC  11 1_555 E DG 5  1_555 -0.319 -1.674 3.459 -2.453  10.675 29.802 -4.984 0.143  2.729 19.929 
4.579   31.709 21 EE_DG110DC111:DG206DC207_FF  E 110 ? F 207 ? E 111 ? F 206 ? 
1 D DC 11 1_555 E DG 5  1_555 D DOC 12 1_555 E DG 4  1_555 -0.128 -1.524 3.398 -0.473  4.356  29.531 -3.870 0.150  3.147 8.486  
0.922   29.847 22 EE_DC111DOC112:DG205DG206_FF E 111 ? F 206 ? E 112 ? F 205 ? 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   1TAQ 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8XK9 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009435 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009435 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005216 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
MG 
N  
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     O  "O5'" . DG    A 1 1   ? 67.844  51.571  3.236   1.00 80.51  ? 101  DG    B "O5'" 1 
ATOM   2     C  "C5'" . DG    A 1 1   ? 68.686  51.919  2.096   1.00 85.71  ? 101  DG    B "C5'" 1 
ATOM   3     C  "C4'" . DG    A 1 1   ? 67.932  51.763  0.791   1.00 81.35  ? 101  DG    B "C4'" 1 
ATOM   4     O  "O4'" . DG    A 1 1   ? 66.952  50.703  0.887   1.00 79.71  ? 101  DG    B "O4'" 1 
ATOM   5     C  "C3'" . DG    A 1 1   ? 67.175  53.004  0.315   1.00 79.23  ? 101  DG    B "C3'" 1 
ATOM   6     O  "O3'" . DG    A 1 1   ? 67.335  53.083  -1.097  1.00 84.17  ? 101  DG    B "O3'" 1 
ATOM   7     C  "C2'" . DG    A 1 1   ? 65.736  52.704  0.726   1.00 75.48  ? 101  DG    B "C2'" 1 
ATOM   8     C  "C1'" . DG    A 1 1   ? 65.661  51.201  0.536   1.00 70.29  ? 101  DG    B "C1'" 1 
ATOM   9     N  N9    . DG    A 1 1   ? 64.666  50.516  1.366   1.00 58.92  ? 101  DG    B N9    1 
ATOM   10    C  C8    . DG    A 1 1   ? 64.384  50.649  2.705   1.00 56.65  ? 101  DG    B C8    1 
ATOM   11    N  N7    . DG    A 1 1   ? 63.425  49.850  3.118   1.00 55.38  ? 101  DG    B N7    1 
ATOM   12    C  C5    . DG    A 1 1   ? 63.057  49.140  1.977   1.00 54.04  ? 101  DG    B C5    1 
ATOM   13    C  C6    . DG    A 1 1   ? 62.082  48.120  1.802   1.00 50.58  ? 101  DG    B C6    1 
ATOM   14    O  O6    . DG    A 1 1   ? 61.321  47.614  2.642   1.00 51.28  ? 101  DG    B O6    1 
ATOM   15    N  N1    . DG    A 1 1   ? 62.034  47.686  0.480   1.00 52.60  ? 101  DG    B N1    1 
ATOM   16    C  C2    . DG    A 1 1   ? 62.833  48.146  -0.540  1.00 55.90  ? 101  DG    B C2    1 
ATOM   17    N  N2    . DG    A 1 1   ? 62.638  47.594  -1.745  1.00 53.51  ? 101  DG    B N2    1 
ATOM   18    N  N3    . DG    A 1 1   ? 63.764  49.089  -0.383  1.00 55.01  ? 101  DG    B N3    1 
ATOM   19    C  C4    . DG    A 1 1   ? 63.820  49.538  0.896   1.00 55.84  ? 101  DG    B C4    1 
ATOM   20    P  P     . DA    A 1 2   ? 66.704  54.370  -1.822  1.00 92.55  ? 102  DA    B P     1 
ATOM   21    O  OP1   . DA    A 1 2   ? 67.689  54.877  -2.837  1.00 89.59  ? 102  DA    B OP1   1 
ATOM   22    O  OP2   . DA    A 1 2   ? 66.124  55.321  -0.804  1.00 89.30  ? 102  DA    B OP2   1 
ATOM   23    O  "O5'" . DA    A 1 2   ? 65.494  53.678  -2.623  1.00 86.11  ? 102  DA    B "O5'" 1 
ATOM   24    C  "C5'" . DA    A 1 2   ? 65.824  52.848  -3.767  1.00 87.17  ? 102  DA    B "C5'" 1 
ATOM   25    C  "C4'" . DA    A 1 2   ? 64.560  52.424  -4.472  1.00 83.23  ? 102  DA    B "C4'" 1 
ATOM   26    O  "O4'" . DA    A 1 2   ? 63.716  51.684  -3.563  1.00 76.40  ? 102  DA    B "O4'" 1 
ATOM   27    C  "C3'" . DA    A 1 2   ? 63.719  53.576  -5.012  1.00 83.14  ? 102  DA    B "C3'" 1 
ATOM   28    O  "O3'" . DA    A 1 2   ? 63.233  53.159  -6.295  1.00 87.14  ? 102  DA    B "O3'" 1 
ATOM   29    C  "C2'" . DA    A 1 2   ? 62.641  53.741  -3.938  1.00 76.24  ? 102  DA    B "C2'" 1 
ATOM   30    C  "C1'" . DA    A 1 2   ? 62.439  52.313  -3.461  1.00 72.22  ? 102  DA    B "C1'" 1 
ATOM   31    N  N9    . DA    A 1 2   ? 61.979  52.144  -2.080  1.00 66.49  ? 102  DA    B N9    1 
ATOM   32    C  C8    . DA    A 1 2   ? 62.347  52.784  -0.917  1.00 61.78  ? 102  DA    B C8    1 
ATOM   33    N  N7    . DA    A 1 2   ? 61.730  52.325  0.147   1.00 56.71  ? 102  DA    B N7    1 
ATOM   34    C  C5    . DA    A 1 2   ? 60.916  51.308  -0.336  1.00 55.03  ? 102  DA    B C5    1 
ATOM   35    C  C6    . DA    A 1 2   ? 60.016  50.421  0.296   1.00 55.34  ? 102  DA    B C6    1 
ATOM   36    N  N6    . DA    A 1 2   ? 59.764  50.420  1.603   1.00 57.76  ? 102  DA    B N6    1 
ATOM   37    N  N1    . DA    A 1 2   ? 59.368  49.523  -0.488  1.00 53.07  ? 102  DA    B N1    1 
ATOM   38    C  C2    . DA    A 1 2   ? 59.610  49.526  -1.807  1.00 54.83  ? 102  DA    B C2    1 
ATOM   39    N  N3    . DA    A 1 2   ? 60.435  50.302  -2.508  1.00 58.06  ? 102  DA    B N3    1 
ATOM   40    C  C4    . DA    A 1 2   ? 61.069  51.180  -1.707  1.00 60.08  ? 102  DA    B C4    1 
ATOM   41    P  P     . DC    A 1 3   ? 62.480  54.307  -7.130  1.00 94.54  ? 103  DC    B P     1 
ATOM   42    O  OP1   . DC    A 1 3   ? 63.244  54.530  -8.405  1.00 87.67  ? 103  DC    B OP1   1 
ATOM   43    O  OP2   . DC    A 1 3   ? 62.278  55.462  -6.179  1.00 82.90  ? 103  DC    B OP2   1 
ATOM   44    O  "O5'" . DC    A 1 3   ? 61.065  53.605  -7.464  1.00 82.04  ? 103  DC    B "O5'" 1 
ATOM   45    C  "C5'" . DC    A 1 3   ? 60.899  52.201  -7.043  1.00 84.42  ? 103  DC    B "C5'" 1 
ATOM   46    C  "C4'" . DC    A 1 3   ? 59.432  51.890  -6.785  1.00 79.09  ? 103  DC    B "C4'" 1 
ATOM   47    O  "O4'" . DC    A 1 3   ? 59.211  51.716  -5.361  1.00 74.33  ? 103  DC    B "O4'" 1 
ATOM   48    C  "C3'" . DC    A 1 3   ? 58.401  52.913  -7.261  1.00 78.75  ? 103  DC    B "C3'" 1 
ATOM   49    O  "O3'" . DC    A 1 3   ? 57.544  52.180  -8.149  1.00 76.39  ? 103  DC    B "O3'" 1 
ATOM   50    C  "C2'" . DC    A 1 3   ? 57.702  53.378  -5.984  1.00 72.87  ? 103  DC    B "C2'" 1 
ATOM   51    C  "C1'" . DC    A 1 3   ? 57.931  52.215  -5.029  1.00 67.62  ? 103  DC    B "C1'" 1 
ATOM   52    N  N1    . DC    A 1 3   ? 57.954  52.570  -3.586  1.00 57.33  ? 103  DC    B N1    1 
ATOM   53    C  C2    . DC    A 1 3   ? 57.205  51.809  -2.679  1.00 57.30  ? 103  DC    B C2    1 
ATOM   54    O  O2    . DC    A 1 3   ? 56.517  50.865  -3.099  1.00 61.12  ? 103  DC    B O2    1 
ATOM   55    N  N3    . DC    A 1 3   ? 57.235  52.138  -1.362  1.00 53.36  ? 103  DC    B N3    1 
ATOM   56    C  C4    . DC    A 1 3   ? 57.968  53.176  -0.936  1.00 47.88  ? 103  DC    B C4    1 
ATOM   57    N  N4    . DC    A 1 3   ? 57.955  53.441  0.361   1.00 47.88  ? 103  DC    B N4    1 
ATOM   58    C  C5    . DC    A 1 3   ? 58.758  53.939  -1.834  1.00 46.55  ? 103  DC    B C5    1 
ATOM   59    C  C6    . DC    A 1 3   ? 58.713  53.611  -3.138  1.00 51.47  ? 103  DC    B C6    1 
ATOM   60    P  P     . DC    A 1 4   ? 56.610  53.067  -9.109  1.00 71.59  ? 104  DC    B P     1 
ATOM   61    O  OP1   . DC    A 1 4   ? 56.179  52.269  -10.309 1.00 75.83  ? 104  DC    B OP1   1 
ATOM   62    O  OP2   . DC    A 1 4   ? 57.244  54.423  -9.272  1.00 60.13  ? 104  DC    B OP2   1 
ATOM   63    O  "O5'" . DC    A 1 4   ? 55.300  53.097  -8.181  1.00 66.74  ? 104  DC    B "O5'" 1 
ATOM   64    C  "C5'" . DC    A 1 4   ? 54.622  51.838  -7.970  1.00 62.19  ? 104  DC    B "C5'" 1 
ATOM   65    C  "C4'" . DC    A 1 4   ? 53.493  52.031  -6.994  1.00 63.62  ? 104  DC    B "C4'" 1 
ATOM   66    O  "O4'" . DC    A 1 4   ? 54.005  52.407  -5.691  1.00 61.25  ? 104  DC    B "O4'" 1 
ATOM   67    C  "C3'" . DC    A 1 4   ? 52.499  53.123  -7.396  1.00 61.13  ? 104  DC    B "C3'" 1 
ATOM   68    O  "O3'" . DC    A 1 4   ? 51.189  52.683  -7.049  1.00 62.91  ? 104  DC    B "O3'" 1 
ATOM   69    C  "C2'" . DC    A 1 4   ? 52.916  54.286  -6.507  1.00 56.02  ? 104  DC    B "C2'" 1 
ATOM   70    C  "C1'" . DC    A 1 4   ? 53.276  53.533  -5.235  1.00 57.37  ? 104  DC    B "C1'" 1 
ATOM   71    N  N1    . DC    A 1 4   ? 54.087  54.276  -4.236  1.00 50.46  ? 104  DC    B N1    1 
ATOM   72    C  C2    . DC    A 1 4   ? 53.918  53.964  -2.879  1.00 49.03  ? 104  DC    B C2    1 
ATOM   73    O  O2    . DC    A 1 4   ? 53.107  53.076  -2.552  1.00 45.56  ? 104  DC    B O2    1 
ATOM   74    N  N3    . DC    A 1 4   ? 54.638  54.646  -1.955  1.00 48.33  ? 104  DC    B N3    1 
ATOM   75    C  C4    . DC    A 1 4   ? 55.498  55.597  -2.333  1.00 52.98  ? 104  DC    B C4    1 
ATOM   76    N  N4    . DC    A 1 4   ? 56.182  56.214  -1.383  1.00 54.25  ? 104  DC    B N4    1 
ATOM   77    C  C5    . DC    A 1 4   ? 55.680  55.932  -3.708  1.00 54.17  ? 104  DC    B C5    1 
ATOM   78    C  C6    . DC    A 1 4   ? 54.961  55.254  -4.616  1.00 52.85  ? 104  DC    B C6    1 
ATOM   79    P  P     . DA    A 1 5   ? 50.188  52.447  -8.280  1.00 58.22  ? 105  DA    B P     1 
ATOM   80    O  OP1   . DA    A 1 5   ? 50.743  51.337  -9.121  1.00 64.34  ? 105  DA    B OP1   1 
ATOM   81    O  OP2   . DA    A 1 5   ? 49.901  53.794  -8.895  1.00 61.40  ? 105  DA    B OP2   1 
ATOM   82    O  "O5'" . DA    A 1 5   ? 48.920  51.909  -7.445  1.00 51.74  ? 105  DA    B "O5'" 1 
ATOM   83    C  "C5'" . DA    A 1 5   ? 49.015  50.586  -6.847  1.00 60.08  ? 105  DA    B "C5'" 1 
ATOM   84    C  "C4'" . DA    A 1 5   ? 48.273  50.547  -5.535  1.00 57.26  ? 105  DA    B "C4'" 1 
ATOM   85    O  "O4'" . DA    A 1 5   ? 48.975  51.326  -4.534  1.00 60.61  ? 105  DA    B "O4'" 1 
ATOM   86    C  "C3'" . DA    A 1 5   ? 46.862  51.122  -5.589  1.00 59.10  ? 105  DA    B "C3'" 1 
ATOM   87    O  "O3'" . DA    A 1 5   ? 46.119  50.405  -4.601  1.00 53.54  ? 105  DA    B "O3'" 1 
ATOM   88    C  "C2'" . DA    A 1 5   ? 47.101  52.587  -5.220  1.00 58.38  ? 105  DA    B "C2'" 1 
ATOM   89    C  "C1'" . DA    A 1 5   ? 48.163  52.440  -4.132  1.00 59.07  ? 105  DA    B "C1'" 1 
ATOM   90    N  N9    . DA    A 1 5   ? 49.061  53.581  -3.931  1.00 52.19  ? 105  DA    B N9    1 
ATOM   91    C  C8    . DA    A 1 5   ? 49.668  54.349  -4.894  1.00 51.26  ? 105  DA    B C8    1 
ATOM   92    N  N7    . DA    A 1 5   ? 50.460  55.270  -4.409  1.00 49.12  ? 105  DA    B N7    1 
ATOM   93    C  C5    . DA    A 1 5   ? 50.405  55.079  -3.037  1.00 50.69  ? 105  DA    B C5    1 
ATOM   94    C  C6    . DA    A 1 5   ? 51.044  55.738  -1.968  1.00 48.79  ? 105  DA    B C6    1 
ATOM   95    N  N6    . DA    A 1 5   ? 51.887  56.753  -2.125  1.00 47.64  ? 105  DA    B N6    1 
ATOM   96    N  N1    . DA    A 1 5   ? 50.765  55.310  -0.717  1.00 49.38  ? 105  DA    B N1    1 
ATOM   97    C  C2    . DA    A 1 5   ? 49.907  54.292  -0.562  1.00 53.55  ? 105  DA    B C2    1 
ATOM   98    N  N3    . DA    A 1 5   ? 49.253  53.596  -1.488  1.00 52.94  ? 105  DA    B N3    1 
ATOM   99    C  C4    . DA    A 1 5   ? 49.545  54.044  -2.725  1.00 53.41  ? 105  DA    B C4    1 
ATOM   100   P  P     . DC    A 1 6   ? 44.524  50.570  -4.659  1.00 60.14  ? 106  DC    B P     1 
ATOM   101   O  OP1   . DC    A 1 6   ? 43.865  49.299  -4.205  1.00 61.16  ? 106  DC    B OP1   1 
ATOM   102   O  OP2   . DC    A 1 6   ? 44.120  51.246  -5.946  1.00 64.10  ? 106  DC    B OP2   1 
ATOM   103   O  "O5'" . DC    A 1 6   ? 44.253  51.646  -3.500  1.00 62.40  ? 106  DC    B "O5'" 1 
ATOM   104   C  "C5'" . DC    A 1 6   ? 44.561  51.280  -2.141  1.00 63.38  ? 106  DC    B "C5'" 1 
ATOM   105   C  "C4'" . DC    A 1 6   ? 44.705  52.523  -1.296  1.00 58.69  ? 106  DC    B "C4'" 1 
ATOM   106   O  "O4'" . DC    A 1 6   ? 45.858  53.307  -1.663  1.00 51.30  ? 106  DC    B "O4'" 1 
ATOM   107   C  "C3'" . DC    A 1 6   ? 43.544  53.499  -1.384  1.00 53.56  ? 106  DC    B "C3'" 1 
ATOM   108   O  "O3'" . DC    A 1 6   ? 42.614  53.026  -0.421  1.00 55.07  ? 106  DC    B "O3'" 1 
ATOM   109   C  "C2'" . DC    A 1 6   ? 44.195  54.839  -1.046  1.00 56.00  ? 106  DC    B "C2'" 1 
ATOM   110   C  "C1'" . DC    A 1 6   ? 45.691  54.544  -1.010  1.00 51.33  ? 106  DC    B "C1'" 1 
ATOM   111   N  N1    . DC    A 1 6   ? 46.527  55.556  -1.697  1.00 47.89  ? 106  DC    B N1    1 
ATOM   112   C  C2    . DC    A 1 6   ? 47.322  56.403  -0.921  1.00 45.77  ? 106  DC    B C2    1 
ATOM   113   O  O2    . DC    A 1 6   ? 47.315  56.260  0.315   1.00 44.01  ? 106  DC    B O2    1 
ATOM   114   N  N3    . DC    A 1 6   ? 48.078  57.341  -1.538  1.00 40.79  ? 106  DC    B N3    1 
ATOM   115   C  C4    . DC    A 1 6   ? 48.032  57.480  -2.865  1.00 43.30  ? 106  DC    B C4    1 
ATOM   116   N  N4    . DC    A 1 6   ? 48.797  58.406  -3.410  1.00 42.20  ? 106  DC    B N4    1 
ATOM   117   C  C5    . DC    A 1 6   ? 47.213  56.643  -3.670  1.00 47.27  ? 106  DC    B C5    1 
ATOM   118   C  C6    . DC    A 1 6   ? 46.483  55.700  -3.048  1.00 48.11  ? 106  DC    B C6    1 
ATOM   119   P  P     . DG    A 1 7   ? 41.249  53.848  -0.259  1.00 56.97  ? 107  DG    B P     1 
ATOM   120   O  OP1   . DG    A 1 7   ? 40.276  52.982  0.476   1.00 56.64  ? 107  DG    B OP1   1 
ATOM   121   O  OP2   . DG    A 1 7   ? 40.913  54.542  -1.553  1.00 58.41  ? 107  DG    B OP2   1 
ATOM   122   O  "O5'" . DG    A 1 7   ? 41.689  54.948  0.824   1.00 59.95  ? 107  DG    B "O5'" 1 
ATOM   123   C  "C5'" . DG    A 1 7   ? 41.943  54.495  2.177   1.00 56.66  ? 107  DG    B "C5'" 1 
ATOM   124   C  "C4'" . DG    A 1 7   ? 42.245  55.669  3.073   1.00 46.82  ? 107  DG    B "C4'" 1 
ATOM   125   O  "O4'" . DG    A 1 7   ? 43.319  56.452  2.510   1.00 46.67  ? 107  DG    B "O4'" 1 
ATOM   126   C  "C3'" . DG    A 1 7   ? 41.081  56.628  3.284   1.00 45.90  ? 107  DG    B "C3'" 1 
ATOM   127   O  "O3'" . DG    A 1 7   ? 41.231  57.072  4.602   1.00 45.19  ? 107  DG    B "O3'" 1 
ATOM   128   C  "C2'" . DG    A 1 7   ? 41.341  57.727  2.256   1.00 45.67  ? 107  DG    B "C2'" 1 
ATOM   129   C  "C1'" . DG    A 1 7   ? 42.862  57.781  2.233   1.00 47.20  ? 107  DG    B "C1'" 1 
ATOM   130   N  N9    . DG    A 1 7   ? 43.450  58.203  0.959   1.00 40.13  ? 107  DG    B N9    1 
ATOM   131   C  C8    . DG    A 1 7   ? 43.074  57.829  -0.307  1.00 44.51  ? 107  DG    B C8    1 
ATOM   132   N  N7    . DG    A 1 7   ? 43.808  58.364  -1.253  1.00 45.07  ? 107  DG    B N7    1 
ATOM   133   C  C5    . DG    A 1 7   ? 44.752  59.116  -0.559  1.00 41.89  ? 107  DG    B C5    1 
ATOM   134   C  C6    . DG    A 1 7   ? 45.803  59.930  -1.049  1.00 40.64  ? 107  DG    B C6    1 
ATOM   135   O  O6    . DG    A 1 7   ? 46.138  60.140  -2.224  1.00 39.59  ? 107  DG    B O6    1 
ATOM   136   N  N1    . DG    A 1 7   ? 46.503  60.537  -0.006  1.00 40.77  ? 107  DG    B N1    1 
ATOM   137   C  C2    . DG    A 1 7   ? 46.230  60.394  1.330   1.00 40.76  ? 107  DG    B C2    1 
ATOM   138   N  N2    . DG    A 1 7   ? 47.026  61.072  2.167   1.00 41.14  ? 107  DG    B N2    1 
ATOM   139   N  N3    . DG    A 1 7   ? 45.221  59.658  1.804   1.00 42.21  ? 107  DG    B N3    1 
ATOM   140   C  C4    . DG    A 1 7   ? 44.532  59.041  0.803   1.00 42.56  ? 107  DG    B C4    1 
ATOM   141   P  P     . DG    A 1 8   ? 39.978  57.797  5.276   1.00 53.36  ? 108  DG    B P     1 
ATOM   142   O  OP1   . DG    A 1 8   ? 40.170  57.640  6.764   1.00 51.57  ? 108  DG    B OP1   1 
ATOM   143   O  OP2   . DG    A 1 8   ? 38.673  57.389  4.638   1.00 54.31  ? 108  DG    B OP2   1 
ATOM   144   O  "O5'" . DG    A 1 8   ? 40.285  59.313  4.841   1.00 49.93  ? 108  DG    B "O5'" 1 
ATOM   145   C  "C5'" . DG    A 1 8   ? 41.277  60.048  5.595   1.00 49.02  ? 108  DG    B "C5'" 1 
ATOM   146   C  "C4'" . DG    A 1 8   ? 41.737  61.257  4.818   1.00 43.08  ? 108  DG    B "C4'" 1 
ATOM   147   O  "O4'" . DG    A 1 8   ? 42.232  60.885  3.517   1.00 42.48  ? 108  DG    B "O4'" 1 
ATOM   148   C  "C3'" . DG    A 1 8   ? 40.640  62.288  4.561   1.00 42.35  ? 108  DG    B "C3'" 1 
ATOM   149   O  "O3'" . DG    A 1 8   ? 40.816  63.324  5.505   1.00 44.24  ? 108  DG    B "O3'" 1 
ATOM   150   C  "C2'" . DG    A 1 8   ? 40.895  62.762  3.133   1.00 39.97  ? 108  DG    B "C2'" 1 
ATOM   151   C  "C1'" . DG    A 1 8   ? 42.221  62.106  2.781   1.00 39.76  ? 108  DG    B "C1'" 1 
ATOM   152   N  N9    . DG    A 1 8   ? 42.376  61.856  1.353   1.00 36.66  ? 108  DG    B N9    1 
ATOM   153   C  C8    . DG    A 1 8   ? 41.590  61.074  0.536   1.00 36.70  ? 108  DG    B C8    1 
ATOM   154   N  N7    . DG    A 1 8   ? 41.978  61.080  -0.724  1.00 34.13  ? 108  DG    B N7    1 
ATOM   155   C  C5    . DG    A 1 8   ? 43.054  61.959  -0.750  1.00 32.39  ? 108  DG    B C5    1 
ATOM   156   C  C6    . DG    A 1 8   ? 43.847  62.401  -1.838  1.00 33.33  ? 108  DG    B C6    1 
ATOM   157   O  O6    . DG    A 1 8   ? 43.800  62.078  -3.031  1.00 39.98  ? 108  DG    B O6    1 
ATOM   158   N  N1    . DG    A 1 8   ? 44.817  63.303  -1.423  1.00 36.97  ? 108  DG    B N1    1 
ATOM   159   C  C2    . DG    A 1 8   ? 45.002  63.737  -0.132  1.00 36.19  ? 108  DG    B C2    1 
ATOM   160   N  N2    . DG    A 1 8   ? 45.999  64.611  0.040   1.00 37.67  ? 108  DG    B N2    1 
ATOM   161   N  N3    . DG    A 1 8   ? 44.250  63.346  0.900   1.00 34.14  ? 108  DG    B N3    1 
ATOM   162   C  C4    . DG    A 1 8   ? 43.305  62.450  0.523   1.00 35.45  ? 108  DG    B C4    1 
ATOM   163   P  P     . DC    A 1 9   ? 39.675  64.445  5.491   1.00 43.57  ? 109  DC    B P     1 
ATOM   164   O  OP1   . DC    A 1 9   ? 39.652  65.228  6.781   1.00 42.79  ? 109  DC    B OP1   1 
ATOM   165   O  OP2   . DC    A 1 9   ? 38.409  63.829  4.973   1.00 41.81  ? 109  DC    B OP2   1 
ATOM   166   O  "O5'" . DC    A 1 9   ? 40.256  65.421  4.358   1.00 45.44  ? 109  DC    B "O5'" 1 
ATOM   167   C  "C5'" . DC    A 1 9   ? 41.510  66.102  4.588   1.00 46.01  ? 109  DC    B "C5'" 1 
ATOM   168   C  "C4'" . DC    A 1 9   ? 41.777  67.018  3.424   1.00 40.48  ? 109  DC    B "C4'" 1 
ATOM   169   O  "O4'" . DC    A 1 9   ? 42.074  66.208  2.263   1.00 43.02  ? 109  DC    B "O4'" 1 
ATOM   170   C  "C3'" . DC    A 1 9   ? 40.598  67.921  3.029   1.00 39.99  ? 109  DC    B "C3'" 1 
ATOM   171   O  "O3'" . DC    A 1 9   ? 41.080  69.197  2.644   1.00 38.31  ? 109  DC    B "O3'" 1 
ATOM   172   C  "C2'" . DC    A 1 9   ? 40.049  67.240  1.787   1.00 37.77  ? 109  DC    B "C2'" 1 
ATOM   173   C  "C1'" . DC    A 1 9   ? 41.355  66.755  1.175   1.00 38.29  ? 109  DC    B "C1'" 1 
ATOM   174   N  N1    . DC    A 1 9   ? 41.213  65.776  0.071   1.00 33.86  ? 109  DC    B N1    1 
ATOM   175   C  C2    . DC    A 1 9   ? 42.043  65.920  -1.045  1.00 36.02  ? 109  DC    B C2    1 
ATOM   176   O  O2    . DC    A 1 9   ? 42.936  66.782  -1.034  1.00 35.28  ? 109  DC    B O2    1 
ATOM   177   N  N3    . DC    A 1 9   ? 41.872  65.110  -2.109  1.00 35.11  ? 109  DC    B N3    1 
ATOM   178   C  C4    . DC    A 1 9   ? 40.906  64.196  -2.110  1.00 37.13  ? 109  DC    B C4    1 
ATOM   179   N  N4    . DC    A 1 9   ? 40.811  63.431  -3.189  1.00 37.87  ? 109  DC    B N4    1 
ATOM   180   C  C5    . DC    A 1 9   ? 40.043  64.035  -0.991  1.00 34.60  ? 109  DC    B C5    1 
ATOM   181   C  C6    . DC    A 1 9   ? 40.226  64.842  0.068   1.00 35.48  ? 109  DC    B C6    1 
ATOM   182   P  P     . DG    A 1 10  ? 40.292  70.458  3.248   1.00 37.36  ? 110  DG    B P     1 
ATOM   183   O  OP1   . DG    A 1 10  ? 40.970  70.979  4.481   1.00 41.34  ? 110  DG    B OP1   1 
ATOM   184   O  OP2   . DG    A 1 10  ? 38.827  70.143  3.233   1.00 35.08  ? 110  DG    B OP2   1 
ATOM   185   O  "O5'" . DG    A 1 10  ? 40.585  71.477  2.047   1.00 33.03  ? 110  DG    B "O5'" 1 
ATOM   186   C  "C5'" . DG    A 1 10  ? 41.693  72.376  2.154   1.00 32.99  ? 110  DG    B "C5'" 1 
ATOM   187   C  "C4'" . DG    A 1 10  ? 42.222  72.690  0.781   1.00 32.17  ? 110  DG    B "C4'" 1 
ATOM   188   O  "O4'" . DG    A 1 10  ? 42.796  71.507  0.181   1.00 32.47  ? 110  DG    B "O4'" 1 
ATOM   189   C  "C3'" . DG    A 1 10  ? 41.177  73.163  -0.223  1.00 32.70  ? 110  DG    B "C3'" 1 
ATOM   190   O  "O3'" . DG    A 1 10  ? 40.903  74.521  0.014   1.00 32.98  ? 110  DG    B "O3'" 1 
ATOM   191   C  "C2'" . DG    A 1 10  ? 41.944  72.942  -1.517  1.00 32.04  ? 110  DG    B "C2'" 1 
ATOM   192   C  "C1'" . DG    A 1 10  ? 42.559  71.579  -1.230  1.00 33.70  ? 110  DG    B "C1'" 1 
ATOM   193   N  N9    . DG    A 1 10  ? 41.690  70.458  -1.593  1.00 34.45  ? 110  DG    B N9    1 
ATOM   194   C  C8    . DG    A 1 10  ? 40.868  69.698  -0.793  1.00 32.99  ? 110  DG    B C8    1 
ATOM   195   N  N7    . DG    A 1 10  ? 40.285  68.713  -1.433  1.00 30.93  ? 110  DG    B N7    1 
ATOM   196   C  C5    . DG    A 1 10  ? 40.744  68.842  -2.741  1.00 32.10  ? 110  DG    B C5    1 
ATOM   197   C  C6    . DG    A 1 10  ? 40.451  68.076  -3.893  1.00 31.94  ? 110  DG    B C6    1 
ATOM   198   O  O6    . DG    A 1 10  ? 39.700  67.096  -3.997  1.00 31.76  ? 110  DG    B O6    1 
ATOM   199   N  N1    . DG    A 1 10  ? 41.174  68.531  -4.996  1.00 33.60  ? 110  DG    B N1    1 
ATOM   200   C  C2    . DG    A 1 10  ? 42.026  69.604  -5.007  1.00 32.15  ? 110  DG    B C2    1 
ATOM   201   N  N2    . DG    A 1 10  ? 42.609  69.904  -6.176  1.00 37.21  ? 110  DG    B N2    1 
ATOM   202   N  N3    . DG    A 1 10  ? 42.302  70.327  -3.930  1.00 28.93  ? 110  DG    B N3    1 
ATOM   203   C  C4    . DG    A 1 10  ? 41.625  69.897  -2.845  1.00 32.52  ? 110  DG    B C4    1 
ATOM   204   P  P     . DC    A 1 11  ? 39.405  75.018  -0.234  1.00 31.52  ? 111  DC    B P     1 
ATOM   205   O  OP1   . DC    A 1 11  ? 39.364  76.430  0.283   1.00 31.28  ? 111  DC    B OP1   1 
ATOM   206   O  OP2   . DC    A 1 11  ? 38.428  74.003  0.254   1.00 28.80  ? 111  DC    B OP2   1 
ATOM   207   O  "O5'" . DC    A 1 11  ? 39.379  74.972  -1.843  1.00 28.66  ? 111  DC    B "O5'" 1 
ATOM   208   C  "C5'" . DC    A 1 11  ? 40.061  76.000  -2.571  1.00 32.02  ? 111  DC    B "C5'" 1 
ATOM   209   C  "C4'" . DC    A 1 11  ? 40.016  75.676  -4.042  1.00 31.02  ? 111  DC    B "C4'" 1 
ATOM   210   O  "O4'" . DC    A 1 11  ? 40.397  74.307  -4.267  1.00 30.84  ? 111  DC    B "O4'" 1 
ATOM   211   C  "C3'" . DC    A 1 11  ? 38.642  75.769  -4.678  1.00 30.00  ? 111  DC    B "C3'" 1 
ATOM   212   O  "O3'" . DC    A 1 11  ? 38.347  77.116  -5.004  1.00 31.61  ? 111  DC    B "O3'" 1 
ATOM   213   C  "C2'" . DC    A 1 11  ? 38.849  74.951  -5.939  1.00 31.82  ? 111  DC    B "C2'" 1 
ATOM   214   C  "C1'" . DC    A 1 11  ? 39.762  73.843  -5.449  1.00 32.15  ? 111  DC    B "C1'" 1 
ATOM   215   N  N1    . DC    A 1 11  ? 39.057  72.586  -5.115  1.00 29.23  ? 111  DC    B N1    1 
ATOM   216   C  C2    . DC    A 1 11  ? 38.739  71.705  -6.150  1.00 28.11  ? 111  DC    B C2    1 
ATOM   217   O  O2    . DC    A 1 11  ? 39.012  71.990  -7.333  1.00 29.32  ? 111  DC    B O2    1 
ATOM   218   N  N3    . DC    A 1 11  ? 38.137  70.554  -5.826  1.00 28.44  ? 111  DC    B N3    1 
ATOM   219   C  C4    . DC    A 1 11  ? 37.830  70.262  -4.559  1.00 28.15  ? 111  DC    B C4    1 
ATOM   220   N  N4    . DC    A 1 11  ? 37.255  69.093  -4.346  1.00 30.45  ? 111  DC    B N4    1 
ATOM   221   C  C5    . DC    A 1 11  ? 38.129  71.147  -3.493  1.00 27.86  ? 111  DC    B C5    1 
ATOM   222   C  C6    . DC    A 1 11  ? 38.740  72.295  -3.815  1.00 29.60  ? 111  DC    B C6    1 
HETATM 223   N  N1    . DOC   A 1 12  ? 35.520  73.285  -8.290  1.00 29.60  ? 112  DOC   B N1    1 
HETATM 224   C  C2    . DOC   A 1 12  ? 35.034  72.055  -8.708  1.00 29.90  ? 112  DOC   B C2    1 
HETATM 225   N  N3    . DOC   A 1 12  ? 34.621  71.170  -7.786  1.00 27.03  ? 112  DOC   B N3    1 
HETATM 226   C  C4    . DOC   A 1 12  ? 34.700  71.441  -6.491  1.00 26.76  ? 112  DOC   B C4    1 
HETATM 227   C  C5    . DOC   A 1 12  ? 35.197  72.687  -6.033  1.00 25.48  ? 112  DOC   B C5    1 
HETATM 228   C  C6    . DOC   A 1 12  ? 35.609  73.569  -6.957  1.00 29.13  ? 112  DOC   B C6    1 
HETATM 229   O  O2    . DOC   A 1 12  ? 34.961  71.826  -9.923  1.00 33.20  ? 112  DOC   B O2    1 
HETATM 230   N  N4    . DOC   A 1 12  ? 34.274  70.491  -5.659  1.00 28.29  ? 112  DOC   B N4    1 
HETATM 231   C  "C1'" . DOC   A 1 12  ? 35.949  74.244  -9.332  1.00 30.09  ? 112  DOC   B "C1'" 1 
HETATM 232   C  "C2'" . DOC   A 1 12  ? 34.810  75.128  -9.825  1.00 28.95  ? 112  DOC   B "C2'" 1 
HETATM 233   C  "C3'" . DOC   A 1 12  ? 35.035  76.423  -9.076  1.00 28.64  ? 112  DOC   B "C3'" 1 
HETATM 234   C  "C4'" . DOC   A 1 12  ? 36.537  76.469  -8.912  1.00 27.46  ? 112  DOC   B "C4'" 1 
HETATM 235   O  "O4'" . DOC   A 1 12  ? 36.942  75.096  -8.769  1.00 28.90  ? 112  DOC   B "O4'" 1 
HETATM 236   C  "C5'" . DOC   A 1 12  ? 37.046  77.212  -7.721  1.00 28.11  ? 112  DOC   B "C5'" 1 
HETATM 237   O  "O5'" . DOC   A 1 12  ? 36.410  76.699  -6.520  1.00 27.99  ? 112  DOC   B "O5'" 1 
HETATM 238   P  P     . DOC   A 1 12  ? 36.780  77.379  -5.087  1.00 27.76  ? 112  DOC   B P     1 
HETATM 239   O  OP1   . DOC   A 1 12  ? 36.617  78.901  -5.251  1.00 23.95  ? 112  DOC   B OP1   1 
HETATM 240   O  OP2   . DOC   A 1 12  ? 35.861  76.706  -4.096  1.00 26.06  ? 112  DOC   B OP2   1 
ATOM   241   C  "C5'" . DA    B 2 1   ? 28.492  49.463  -4.764  1.00 135.93 ? 202  DA    C "C5'" 1 
ATOM   242   C  "C4'" . DA    B 2 1   ? 28.777  50.065  -3.408  1.00 154.41 ? 202  DA    C "C4'" 1 
ATOM   243   O  "O4'" . DA    B 2 1   ? 30.202  50.045  -3.156  1.00 153.42 ? 202  DA    C "O4'" 1 
ATOM   244   C  "C3'" . DA    B 2 1   ? 28.371  51.528  -3.226  1.00 160.03 ? 202  DA    C "C3'" 1 
ATOM   245   O  "O3'" . DA    B 2 1   ? 26.963  51.727  -2.957  1.00 166.59 ? 202  DA    C "O3'" 1 
ATOM   246   C  "C2'" . DA    B 2 1   ? 29.249  51.887  -2.027  1.00 152.16 ? 202  DA    C "C2'" 1 
ATOM   247   C  "C1'" . DA    B 2 1   ? 30.562  51.182  -2.363  1.00 151.21 ? 202  DA    C "C1'" 1 
ATOM   248   N  N9    . DA    B 2 1   ? 31.502  52.033  -3.108  1.00 142.63 ? 202  DA    C N9    1 
ATOM   249   C  C8    . DA    B 2 1   ? 31.903  53.290  -2.714  1.00 129.15 ? 202  DA    C C8    1 
ATOM   250   N  N7    . DA    B 2 1   ? 32.711  53.873  -3.565  1.00 124.89 ? 202  DA    C N7    1 
ATOM   251   C  C5    . DA    B 2 1   ? 32.861  52.950  -4.593  1.00 129.03 ? 202  DA    C C5    1 
ATOM   252   C  C6    . DA    B 2 1   ? 33.599  52.979  -5.797  1.00 114.03 ? 202  DA    C C6    1 
ATOM   253   N  N6    . DA    B 2 1   ? 34.347  54.007  -6.182  1.00 105.81 ? 202  DA    C N6    1 
ATOM   254   N  N1    . DA    B 2 1   ? 33.530  51.892  -6.606  1.00 118.25 ? 202  DA    C N1    1 
ATOM   255   C  C2    . DA    B 2 1   ? 32.769  50.858  -6.219  1.00 126.26 ? 202  DA    C C2    1 
ATOM   256   N  N3    . DA    B 2 1   ? 32.033  50.720  -5.116  1.00 134.74 ? 202  DA    C N3    1 
ATOM   257   C  C4    . DA    B 2 1   ? 32.119  51.810  -4.327  1.00 140.78 ? 202  DA    C C4    1 
ATOM   258   P  P     . DA    B 2 2   ? 26.030  52.483  -4.044  1.00 159.01 ? 203  DA    C P     1 
ATOM   259   O  OP1   . DA    B 2 2   ? 24.622  52.639  -3.526  1.00 132.15 ? 203  DA    C OP1   1 
ATOM   260   O  OP2   . DA    B 2 2   ? 26.178  51.835  -5.395  1.00 153.87 ? 203  DA    C OP2   1 
ATOM   261   O  "O5'" . DA    B 2 2   ? 26.604  53.987  -4.114  1.00 142.92 ? 203  DA    C "O5'" 1 
ATOM   262   C  "C5'" . DA    B 2 2   ? 27.041  54.674  -2.901  1.00 111.70 ? 203  DA    C "C5'" 1 
ATOM   263   C  "C4'" . DA    B 2 2   ? 28.049  55.742  -3.261  1.00 86.85  ? 203  DA    C "C4'" 1 
ATOM   264   O  "O4'" . DA    B 2 2   ? 29.194  55.161  -3.933  1.00 83.50  ? 203  DA    C "O4'" 1 
ATOM   265   C  "C3'" . DA    B 2 2   ? 27.514  56.810  -4.205  1.00 72.84  ? 203  DA    C "C3'" 1 
ATOM   266   O  "O3'" . DA    B 2 2   ? 28.157  58.030  -3.910  1.00 57.80  ? 203  DA    C "O3'" 1 
ATOM   267   C  "C2'" . DA    B 2 2   ? 27.973  56.314  -5.568  1.00 74.02  ? 203  DA    C "C2'" 1 
ATOM   268   C  "C1'" . DA    B 2 2   ? 29.339  55.729  -5.238  1.00 77.47  ? 203  DA    C "C1'" 1 
ATOM   269   N  N9    . DA    B 2 2   ? 29.761  54.707  -6.208  1.00 77.86  ? 203  DA    C N9    1 
ATOM   270   C  C8    . DA    B 2 2   ? 29.267  53.428  -6.276  1.00 72.85  ? 203  DA    C C8    1 
ATOM   271   N  N7    . DA    B 2 2   ? 29.751  52.725  -7.266  1.00 71.67  ? 203  DA    C N7    1 
ATOM   272   C  C5    . DA    B 2 2   ? 30.608  53.593  -7.919  1.00 78.81  ? 203  DA    C C5    1 
ATOM   273   C  C6    . DA    B 2 2   ? 31.421  53.431  -9.063  1.00 90.19  ? 203  DA    C C6    1 
ATOM   274   N  N6    . DA    B 2 2   ? 31.498  52.290  -9.751  1.00 83.72  ? 203  DA    C N6    1 
ATOM   275   N  N1    . DA    B 2 2   ? 32.147  54.504  -9.475  1.00 84.13  ? 203  DA    C N1    1 
ATOM   276   C  C2    . DA    B 2 2   ? 32.045  55.646  -8.776  1.00 87.39  ? 203  DA    C C2    1 
ATOM   277   N  N3    . DA    B 2 2   ? 31.313  55.911  -7.691  1.00 87.60  ? 203  DA    C N3    1 
ATOM   278   C  C4    . DA    B 2 2   ? 30.610  54.830  -7.295  1.00 80.33  ? 203  DA    C C4    1 
ATOM   279   P  P     . DC    B 2 3   ? 27.214  59.264  -3.520  1.00 49.50  ? 204  DC    C P     1 
ATOM   280   O  OP1   . DC    B 2 3   ? 28.118  60.239  -2.808  1.00 50.56  ? 204  DC    C OP1   1 
ATOM   281   O  OP2   . DC    B 2 3   ? 25.843  58.810  -3.070  1.00 43.13  ? 204  DC    C OP2   1 
ATOM   282   O  "O5'" . DC    B 2 3   ? 26.979  59.971  -4.937  1.00 46.05  ? 204  DC    C "O5'" 1 
ATOM   283   C  "C5'" . DC    B 2 3   ? 28.052  60.743  -5.483  1.00 40.48  ? 204  DC    C "C5'" 1 
ATOM   284   C  "C4'" . DC    B 2 3   ? 27.526  61.446  -6.701  1.00 37.29  ? 204  DC    C "C4'" 1 
ATOM   285   O  "O4'" . DC    B 2 3   ? 26.894  62.678  -6.305  1.00 35.62  ? 204  DC    C "O4'" 1 
ATOM   286   C  "C3'" . DC    B 2 3   ? 28.598  61.818  -7.714  1.00 34.97  ? 204  DC    C "C3'" 1 
ATOM   287   O  "O3'" . DC    B 2 3   ? 28.749  60.698  -8.589  1.00 32.38  ? 204  DC    C "O3'" 1 
ATOM   288   C  "C2'" . DC    B 2 3   ? 27.965  63.033  -8.372  1.00 32.28  ? 204  DC    C "C2'" 1 
ATOM   289   C  "C1'" . DC    B 2 3   ? 27.279  63.709  -7.201  1.00 35.28  ? 204  DC    C "C1'" 1 
ATOM   290   N  N1    . DC    B 2 3   ? 28.124  64.654  -6.438  1.00 35.57  ? 204  DC    C N1    1 
ATOM   291   C  C2    . DC    B 2 3   ? 28.390  65.915  -6.969  1.00 35.23  ? 204  DC    C C2    1 
ATOM   292   O  O2    . DC    B 2 3   ? 27.954  66.197  -8.095  1.00 34.65  ? 204  DC    C O2    1 
ATOM   293   N  N3    . DC    B 2 3   ? 29.163  66.774  -6.250  1.00 35.86  ? 204  DC    C N3    1 
ATOM   294   C  C4    . DC    B 2 3   ? 29.632  66.429  -5.042  1.00 34.88  ? 204  DC    C C4    1 
ATOM   295   N  N4    . DC    B 2 3   ? 30.367  67.315  -4.383  1.00 35.64  ? 204  DC    C N4    1 
ATOM   296   C  C5    . DC    B 2 3   ? 29.361  65.155  -4.484  1.00 33.66  ? 204  DC    C C5    1 
ATOM   297   C  C6    . DC    B 2 3   ? 28.611  64.308  -5.205  1.00 36.46  ? 204  DC    C C6    1 
ATOM   298   P  P     . DG    B 2 4   ? 30.223  60.371  -9.111  1.00 31.25  ? 205  DG    C P     1 
ATOM   299   O  OP1   . DG    B 2 4   ? 30.065  59.107  -9.912  1.00 31.26  ? 205  DG    C OP1   1 
ATOM   300   O  OP2   . DG    B 2 4   ? 31.189  60.495  -7.969  1.00 34.21  ? 205  DG    C OP2   1 
ATOM   301   O  "O5'" . DG    B 2 4   ? 30.563  61.624  -10.045 1.00 30.53  ? 205  DG    C "O5'" 1 
ATOM   302   C  "C5'" . DG    B 2 4   ? 30.002  61.644  -11.377 1.00 32.38  ? 205  DG    C "C5'" 1 
ATOM   303   C  "C4'" . DG    B 2 4   ? 30.405  62.935  -12.031 1.00 30.60  ? 205  DG    C "C4'" 1 
ATOM   304   O  "O4'" . DG    B 2 4   ? 30.052  64.020  -11.160 1.00 30.14  ? 205  DG    C "O4'" 1 
ATOM   305   C  "C3'" . DG    B 2 4   ? 31.914  63.071  -12.223 1.00 31.61  ? 205  DG    C "C3'" 1 
ATOM   306   O  "O3'" . DG    B 2 4   ? 32.286  62.463  -13.446 1.00 30.56  ? 205  DG    C "O3'" 1 
ATOM   307   C  "C2'" . DG    B 2 4   ? 32.091  64.582  -12.272 1.00 33.07  ? 205  DG    C "C2'" 1 
ATOM   308   C  "C1'" . DG    B 2 4   ? 31.017  65.063  -11.308 1.00 32.62  ? 205  DG    C "C1'" 1 
ATOM   309   N  N9    . DG    B 2 4   ? 31.502  65.417  -9.981  1.00 31.40  ? 205  DG    C N9    1 
ATOM   310   C  C8    . DG    B 2 4   ? 31.383  64.746  -8.790  1.00 33.87  ? 205  DG    C C8    1 
ATOM   311   N  N7    . DG    B 2 4   ? 31.892  65.402  -7.772  1.00 31.35  ? 205  DG    C N7    1 
ATOM   312   C  C5    . DG    B 2 4   ? 32.365  66.584  -8.321  1.00 30.35  ? 205  DG    C C5    1 
ATOM   313   C  C6    . DG    B 2 4   ? 33.016  67.688  -7.711  1.00 32.15  ? 205  DG    C C6    1 
ATOM   314   O  O6    . DG    B 2 4   ? 33.295  67.870  -6.515  1.00 36.43  ? 205  DG    C O6    1 
ATOM   315   N  N1    . DG    B 2 4   ? 33.335  68.664  -8.657  1.00 32.50  ? 205  DG    C N1    1 
ATOM   316   C  C2    . DG    B 2 4   ? 33.055  68.594  -10.006 1.00 31.57  ? 205  DG    C C2    1 
ATOM   317   N  N2    . DG    B 2 4   ? 33.412  69.636  -10.758 1.00 27.87  ? 205  DG    C N2    1 
ATOM   318   N  N3    . DG    B 2 4   ? 32.444  67.564  -10.582 1.00 35.34  ? 205  DG    C N3    1 
ATOM   319   C  C4    . DG    B 2 4   ? 32.132  66.599  -9.683  1.00 32.75  ? 205  DG    C C4    1 
ATOM   320   P  P     . DG    B 2 5   ? 33.822  62.022  -13.511 1.00 31.64  ? 206  DG    C P     1 
ATOM   321   O  OP1   . DG    B 2 5   ? 33.971  61.456  -14.895 1.00 34.90  ? 206  DG    C OP1   1 
ATOM   322   O  OP2   . DG    B 2 5   ? 34.137  61.219  -12.281 1.00 35.09  ? 206  DG    C OP2   1 
ATOM   323   O  "O5'" . DG    B 2 5   ? 34.597  63.418  -13.446 1.00 29.95  ? 206  DG    C "O5'" 1 
ATOM   324   C  "C5'" . DG    B 2 5   ? 34.698  64.180  -14.659 1.00 30.99  ? 206  DG    C "C5'" 1 
ATOM   325   C  "C4'" . DG    B 2 5   ? 35.459  65.448  -14.367 1.00 33.48  ? 206  DG    C "C4'" 1 
ATOM   326   O  "O4'" . DG    B 2 5   ? 34.904  66.146  -13.230 1.00 30.55  ? 206  DG    C "O4'" 1 
ATOM   327   C  "C3'" . DG    B 2 5   ? 36.924  65.245  -14.007 1.00 33.66  ? 206  DG    C "C3'" 1 
ATOM   328   O  "O3'" . DG    B 2 5   ? 37.659  65.030  -15.202 1.00 37.50  ? 206  DG    C "O3'" 1 
ATOM   329   C  "C2'" . DG    B 2 5   ? 37.243  66.599  -13.383 1.00 36.14  ? 206  DG    C "C2'" 1 
ATOM   330   C  "C1'" . DG    B 2 5   ? 35.951  66.924  -12.631 1.00 32.05  ? 206  DG    C "C1'" 1 
ATOM   331   N  N9    . DG    B 2 5   ? 35.982  66.644  -11.189 1.00 30.85  ? 206  DG    C N9    1 
ATOM   332   C  C8    . DG    B 2 5   ? 35.525  65.569  -10.460 1.00 28.77  ? 206  DG    C C8    1 
ATOM   333   N  N7    . DG    B 2 5   ? 35.712  65.708  -9.164  1.00 29.53  ? 206  DG    C N7    1 
ATOM   334   C  C5    . DG    B 2 5   ? 36.306  66.960  -9.025  1.00 27.44  ? 206  DG    C C5    1 
ATOM   335   C  C6    . DG    B 2 5   ? 36.723  67.666  -7.864  1.00 26.78  ? 206  DG    C C6    1 
ATOM   336   O  O6    . DG    B 2 5   ? 36.606  67.368  -6.659  1.00 29.14  ? 206  DG    C O6    1 
ATOM   337   N  N1    . DG    B 2 5   ? 37.322  68.865  -8.209  1.00 26.48  ? 206  DG    C N1    1 
ATOM   338   C  C2    . DG    B 2 5   ? 37.454  69.375  -9.480  1.00 28.29  ? 206  DG    C C2    1 
ATOM   339   N  N2    . DG    B 2 5   ? 38.039  70.577  -9.595  1.00 28.33  ? 206  DG    C N2    1 
ATOM   340   N  N3    . DG    B 2 5   ? 37.043  68.736  -10.572 1.00 29.17  ? 206  DG    C N3    1 
ATOM   341   C  C4    . DG    B 2 5   ? 36.489  67.534  -10.269 1.00 29.86  ? 206  DG    C C4    1 
ATOM   342   P  P     . DC    B 2 6   ? 39.093  64.361  -14.961 1.00 33.16  ? 207  DC    C P     1 
ATOM   343   O  OP1   . DC    B 2 6   ? 39.553  63.882  -16.301 1.00 33.35  ? 207  DC    C OP1   1 
ATOM   344   O  OP2   . DC    B 2 6   ? 39.052  63.492  -13.734 1.00 38.15  ? 207  DC    C OP2   1 
ATOM   345   O  "O5'" . DC    B 2 6   ? 39.899  65.675  -14.541 1.00 36.75  ? 207  DC    C "O5'" 1 
ATOM   346   C  "C5'" . DC    B 2 6   ? 41.155  65.526  -13.849 1.00 33.91  ? 207  DC    C "C5'" 1 
ATOM   347   C  "C4'" . DC    B 2 6   ? 41.474  66.826  -13.165 1.00 30.89  ? 207  DC    C "C4'" 1 
ATOM   348   O  "O4'" . DC    B 2 6   ? 40.489  67.088  -12.144 1.00 29.11  ? 207  DC    C "O4'" 1 
ATOM   349   C  "C3'" . DC    B 2 6   ? 42.810  66.833  -12.455 1.00 31.10  ? 207  DC    C "C3'" 1 
ATOM   350   O  "O3'" . DC    B 2 6   ? 43.742  67.296  -13.401 1.00 30.54  ? 207  DC    C "O3'" 1 
ATOM   351   C  "C2'" . DC    B 2 6   ? 42.597  67.798  -11.288 1.00 30.01  ? 207  DC    C "C2'" 1 
ATOM   352   C  "C1'" . DC    B 2 6   ? 41.090  67.768  -11.061 1.00 29.19  ? 207  DC    C "C1'" 1 
ATOM   353   N  N1    . DC    B 2 6   ? 40.647  67.081  -9.842  1.00 26.31  ? 207  DC    C N1    1 
ATOM   354   C  C2    . DC    B 2 6   ? 40.838  67.711  -8.620  1.00 27.30  ? 207  DC    C C2    1 
ATOM   355   O  O2    . DC    B 2 6   ? 41.466  68.783  -8.605  1.00 27.09  ? 207  DC    C O2    1 
ATOM   356   N  N3    . DC    B 2 6   ? 40.387  67.104  -7.498  1.00 27.59  ? 207  DC    C N3    1 
ATOM   357   C  C4    . DC    B 2 6   ? 39.752  65.923  -7.570  1.00 29.22  ? 207  DC    C C4    1 
ATOM   358   N  N4    . DC    B 2 6   ? 39.326  65.365  -6.448  1.00 30.07  ? 207  DC    C N4    1 
ATOM   359   C  C5    . DC    B 2 6   ? 39.532  65.279  -8.808  1.00 28.52  ? 207  DC    C C5    1 
ATOM   360   C  C6    . DC    B 2 6   ? 39.970  65.902  -9.912  1.00 30.51  ? 207  DC    C C6    1 
ATOM   361   P  P     . DG    B 2 7   ? 45.192  66.646  -13.196 1.00 29.58  ? 208  DG    C P     1 
ATOM   362   O  OP1   . DG    B 2 7   ? 46.003  67.282  -14.281 1.00 28.85  ? 208  DG    C OP1   1 
ATOM   363   O  OP2   . DG    B 2 7   ? 45.079  65.155  -13.053 1.00 29.49  ? 208  DG    C OP2   1 
ATOM   364   O  "O5'" . DG    B 2 7   ? 45.594  67.243  -11.764 1.00 29.32  ? 208  DG    C "O5'" 1 
ATOM   365   C  "C5'" . DG    B 2 7   ? 46.018  68.626  -11.716 1.00 31.67  ? 208  DG    C "C5'" 1 
ATOM   366   C  "C4'" . DG    B 2 7   ? 46.523  68.928  -10.328 1.00 31.13  ? 208  DG    C "C4'" 1 
ATOM   367   O  "O4'" . DG    B 2 7   ? 45.519  68.493  -9.396  1.00 28.32  ? 208  DG    C "O4'" 1 
ATOM   368   C  "C3'" . DG    B 2 7   ? 47.835  68.223  -9.940  1.00 32.16  ? 208  DG    C "C3'" 1 
ATOM   369   O  "O3'" . DG    B 2 7   ? 48.659  69.147  -9.217  1.00 34.74  ? 208  DG    C "O3'" 1 
ATOM   370   C  "C2'" . DG    B 2 7   ? 47.343  67.055  -9.086  1.00 29.64  ? 208  DG    C "C2'" 1 
ATOM   371   C  "C1'" . DG    B 2 7   ? 46.123  67.660  -8.409  1.00 30.59  ? 208  DG    C "C1'" 1 
ATOM   372   N  N9    . DG    B 2 7   ? 45.130  66.682  -7.972  1.00 28.74  ? 208  DG    C N9    1 
ATOM   373   C  C8    . DG    B 2 7   ? 44.592  65.699  -8.767  1.00 30.23  ? 208  DG    C C8    1 
ATOM   374   N  N7    . DG    B 2 7   ? 43.734  64.932  -8.137  1.00 29.66  ? 208  DG    C N7    1 
ATOM   375   C  C5    . DG    B 2 7   ? 43.707  65.445  -6.844  1.00 28.00  ? 208  DG    C C5    1 
ATOM   376   C  C6    . DG    B 2 7   ? 42.972  65.014  -5.718  1.00 30.91  ? 208  DG    C C6    1 
ATOM   377   O  O6    . DG    B 2 7   ? 42.164  64.076  -5.633  1.00 34.07  ? 208  DG    C O6    1 
ATOM   378   N  N1    . DG    B 2 7   ? 43.240  65.805  -4.601  1.00 30.67  ? 208  DG    C N1    1 
ATOM   379   C  C2    . DG    B 2 7   ? 44.111  66.862  -4.572  1.00 29.89  ? 208  DG    C C2    1 
ATOM   380   N  N2    . DG    B 2 7   ? 44.233  67.483  -3.391  1.00 32.69  ? 208  DG    C N2    1 
ATOM   381   N  N3    . DG    B 2 7   ? 44.812  67.272  -5.627  1.00 29.26  ? 208  DG    C N3    1 
ATOM   382   C  C4    . DG    B 2 7   ? 44.561  66.521  -6.727  1.00 28.73  ? 208  DG    C C4    1 
ATOM   383   P  P     . DC    B 2 8   ? 50.154  68.777  -8.748  1.00 33.56  ? 209  DC    C P     1 
ATOM   384   O  OP1   . DC    B 2 8   ? 51.032  69.992  -8.909  1.00 35.02  ? 209  DC    C OP1   1 
ATOM   385   O  OP2   . DC    B 2 8   ? 50.597  67.474  -9.365  1.00 35.73  ? 209  DC    C OP2   1 
ATOM   386   O  "O5'" . DC    B 2 8   ? 49.798  68.447  -7.222  1.00 32.21  ? 209  DC    C "O5'" 1 
ATOM   387   C  "C5'" . DC    B 2 8   ? 49.429  69.535  -6.357  1.00 36.43  ? 209  DC    C "C5'" 1 
ATOM   388   C  "C4'" . DC    B 2 8   ? 49.572  69.121  -4.911  1.00 35.68  ? 209  DC    C "C4'" 1 
ATOM   389   O  "O4'" . DC    B 2 8   ? 48.489  68.244  -4.516  1.00 36.85  ? 209  DC    C "O4'" 1 
ATOM   390   C  "C3'" . DC    B 2 8   ? 50.866  68.386  -4.567  1.00 34.46  ? 209  DC    C "C3'" 1 
ATOM   391   O  "O3'" . DC    B 2 8   ? 51.280  68.815  -3.273  1.00 38.24  ? 209  DC    C "O3'" 1 
ATOM   392   C  "C2'" . DC    B 2 8   ? 50.415  66.938  -4.530  1.00 35.26  ? 209  DC    C "C2'" 1 
ATOM   393   C  "C1'" . DC    B 2 8   ? 49.027  67.073  -3.928  1.00 35.53  ? 209  DC    C "C1'" 1 
ATOM   394   N  N1    . DC    B 2 8   ? 48.099  65.956  -4.222  1.00 31.53  ? 209  DC    C N1    1 
ATOM   395   C  C2    . DC    B 2 8   ? 47.255  65.497  -3.207  1.00 32.57  ? 209  DC    C C2    1 
ATOM   396   O  O2    . DC    B 2 8   ? 47.320  65.998  -2.069  1.00 33.53  ? 209  DC    C O2    1 
ATOM   397   N  N3    . DC    B 2 8   ? 46.386  64.503  -3.491  1.00 31.11  ? 209  DC    C N3    1 
ATOM   398   C  C4    . DC    B 2 8   ? 46.339  63.964  -4.715  1.00 31.73  ? 209  DC    C C4    1 
ATOM   399   N  N4    . DC    B 2 8   ? 45.456  62.995  -4.911  1.00 33.87  ? 209  DC    C N4    1 
ATOM   400   C  C5    . DC    B 2 8   ? 47.182  64.420  -5.765  1.00 31.48  ? 209  DC    C C5    1 
ATOM   401   C  C6    . DC    B 2 8   ? 48.031  65.422  -5.481  1.00 32.18  ? 209  DC    C C6    1 
ATOM   402   P  P     . DC    B 2 9   ? 52.764  68.469  -2.731  1.00 36.02  ? 210  DC    C P     1 
ATOM   403   O  OP1   . DC    B 2 9   ? 53.276  69.790  -2.234  1.00 41.71  ? 210  DC    C OP1   1 
ATOM   404   O  OP2   . DC    B 2 9   ? 53.551  67.637  -3.705  1.00 34.47  ? 210  DC    C OP2   1 
ATOM   405   O  "O5'" . DC    B 2 9   ? 52.317  67.592  -1.467  1.00 32.37  ? 210  DC    C "O5'" 1 
ATOM   406   C  "C5'" . DC    B 2 9   ? 51.627  68.306  -0.414  1.00 37.68  ? 210  DC    C "C5'" 1 
ATOM   407   C  "C4'" . DC    B 2 9   ? 51.242  67.337  0.674   1.00 42.72  ? 210  DC    C "C4'" 1 
ATOM   408   O  "O4'" . DC    B 2 9   ? 50.153  66.503  0.232   1.00 42.67  ? 210  DC    C "O4'" 1 
ATOM   409   C  "C3'" . DC    B 2 9   ? 52.387  66.419  1.091   1.00 45.29  ? 210  DC    C "C3'" 1 
ATOM   410   O  "O3'" . DC    B 2 9   ? 52.773  66.730  2.434   1.00 54.50  ? 210  DC    C "O3'" 1 
ATOM   411   C  "C2'" . DC    B 2 9   ? 51.808  65.013  1.025   1.00 49.29  ? 210  DC    C "C2'" 1 
ATOM   412   C  "C1'" . DC    B 2 9   ? 50.330  65.183  0.701   1.00 45.57  ? 210  DC    C "C1'" 1 
ATOM   413   N  N1    . DC    B 2 9   ? 49.878  64.260  -0.370  1.00 38.72  ? 210  DC    C N1    1 
ATOM   414   C  C2    . DC    B 2 9   ? 48.966  63.245  -0.071  1.00 37.23  ? 210  DC    C C2    1 
ATOM   415   O  O2    . DC    B 2 9   ? 48.512  63.162  1.080   1.00 38.48  ? 210  DC    C O2    1 
ATOM   416   N  N3    . DC    B 2 9   ? 48.550  62.422  -1.060  1.00 34.90  ? 210  DC    C N3    1 
ATOM   417   C  C4    . DC    B 2 9   ? 49.058  62.529  -2.286  1.00 36.39  ? 210  DC    C C4    1 
ATOM   418   N  N4    . DC    B 2 9   ? 48.602  61.698  -3.214  1.00 39.79  ? 210  DC    C N4    1 
ATOM   419   C  C5    . DC    B 2 9   ? 50.017  63.529  -2.598  1.00 39.90  ? 210  DC    C C5    1 
ATOM   420   C  C6    . DC    B 2 9   ? 50.392  64.369  -1.620  1.00 38.45  ? 210  DC    C C6    1 
ATOM   421   P  P     . DG    B 2 10  ? 54.124  66.026  2.972   1.00 48.88  ? 211  DG    C P     1 
ATOM   422   O  OP1   . DG    B 2 10  ? 54.651  66.999  3.992   1.00 62.62  ? 211  DG    C OP1   1 
ATOM   423   O  OP2   . DG    B 2 10  ? 54.960  65.479  1.837   1.00 39.75  ? 211  DG    C OP2   1 
ATOM   424   O  "O5'" . DG    B 2 10  ? 53.538  64.765  3.781   1.00 41.54  ? 211  DG    C "O5'" 1 
ATOM   425   C  "C5'" . DG    B 2 10  ? 52.596  65.009  4.857   1.00 42.18  ? 211  DG    C "C5'" 1 
ATOM   426   C  "C4'" . DG    B 2 10  ? 52.082  63.684  5.352   1.00 42.59  ? 211  DG    C "C4'" 1 
ATOM   427   O  "O4'" . DG    B 2 10  ? 51.370  63.002  4.294   1.00 45.18  ? 211  DG    C "O4'" 1 
ATOM   428   C  "C3'" . DG    B 2 10  ? 53.172  62.719  5.819   1.00 44.24  ? 211  DG    C "C3'" 1 
ATOM   429   O  "O3'" . DG    B 2 10  ? 52.632  62.016  6.941   1.00 48.07  ? 211  DG    C "O3'" 1 
ATOM   430   C  "C2'" . DG    B 2 10  ? 53.382  61.822  4.601   1.00 42.62  ? 211  DG    C "C2'" 1 
ATOM   431   C  "C1'" . DG    B 2 10  ? 51.978  61.742  4.013   1.00 40.45  ? 211  DG    C "C1'" 1 
ATOM   432   N  N9    . DG    B 2 10  ? 51.946  61.504  2.566   1.00 35.99  ? 211  DG    C N9    1 
ATOM   433   C  C8    . DG    B 2 10  ? 52.701  62.094  1.578   1.00 36.29  ? 211  DG    C C8    1 
ATOM   434   N  N7    . DG    B 2 10  ? 52.447  61.639  0.371   1.00 31.82  ? 211  DG    C N7    1 
ATOM   435   C  C5    . DG    B 2 10  ? 51.447  60.697  0.571   1.00 34.15  ? 211  DG    C C5    1 
ATOM   436   C  C6    . DG    B 2 10  ? 50.766  59.880  -0.378  1.00 35.75  ? 211  DG    C C6    1 
ATOM   437   O  O6    . DG    B 2 10  ? 50.896  59.844  -1.623  1.00 32.63  ? 211  DG    C O6    1 
ATOM   438   N  N1    . DG    B 2 10  ? 49.848  59.047  0.265   1.00 32.89  ? 211  DG    C N1    1 
ATOM   439   C  C2    . DG    B 2 10  ? 49.610  59.007  1.624   1.00 35.62  ? 211  DG    C C2    1 
ATOM   440   N  N2    . DG    B 2 10  ? 48.694  58.124  2.046   1.00 32.72  ? 211  DG    C N2    1 
ATOM   441   N  N3    . DG    B 2 10  ? 50.221  59.793  2.515   1.00 35.38  ? 211  DG    C N3    1 
ATOM   442   C  C4    . DG    B 2 10  ? 51.150  60.585  1.920   1.00 35.91  ? 211  DG    C C4    1 
ATOM   443   P  P     . DT    B 2 11  ? 53.568  60.924  7.652   1.00 39.15  ? 212  DT    C P     1 
ATOM   444   O  OP1   . DT    B 2 11  ? 53.262  61.075  9.116   1.00 40.41  ? 212  DT    C OP1   1 
ATOM   445   O  OP2   . DT    B 2 11  ? 54.958  60.999  7.069   1.00 41.89  ? 212  DT    C OP2   1 
ATOM   446   O  "O5'" . DT    B 2 11  ? 52.820  59.602  7.114   1.00 38.51  ? 212  DT    C "O5'" 1 
ATOM   447   C  "C5'" . DT    B 2 11  ? 51.482  59.348  7.635   1.00 44.76  ? 212  DT    C "C5'" 1 
ATOM   448   C  "C4'" . DT    B 2 11  ? 50.975  58.030  7.111   1.00 45.81  ? 212  DT    C "C4'" 1 
ATOM   449   O  "O4'" . DT    B 2 11  ? 51.010  58.029  5.668   1.00 45.11  ? 212  DT    C "O4'" 1 
ATOM   450   C  "C3'" . DT    B 2 11  ? 51.803  56.830  7.564   1.00 45.71  ? 212  DT    C "C3'" 1 
ATOM   451   O  "O3'" . DT    B 2 11  ? 50.901  55.894  8.133   1.00 55.92  ? 212  DT    C "O3'" 1 
ATOM   452   C  "C2'" . DT    B 2 11  ? 52.459  56.319  6.286   1.00 44.79  ? 212  DT    C "C2'" 1 
ATOM   453   C  "C1'" . DT    B 2 11  ? 51.471  56.762  5.227   1.00 42.10  ? 212  DT    C "C1'" 1 
ATOM   454   N  N1    . DT    B 2 11  ? 52.023  56.959  3.879   1.00 40.95  ? 212  DT    C N1    1 
ATOM   455   C  C2    . DT    B 2 11  ? 51.463  56.244  2.841   1.00 43.85  ? 212  DT    C C2    1 
ATOM   456   O  O2    . DT    B 2 11  ? 50.563  55.427  3.006   1.00 41.31  ? 212  DT    C O2    1 
ATOM   457   N  N3    . DT    B 2 11  ? 52.025  56.486  1.611   1.00 41.74  ? 212  DT    C N3    1 
ATOM   458   C  C4    . DT    B 2 11  ? 53.044  57.376  1.311   1.00 41.75  ? 212  DT    C C4    1 
ATOM   459   O  O4    . DT    B 2 11  ? 53.440  57.515  0.136   1.00 40.97  ? 212  DT    C O4    1 
ATOM   460   C  C5    . DT    B 2 11  ? 53.592  58.078  2.447   1.00 41.04  ? 212  DT    C C5    1 
ATOM   461   C  C7    . DT    B 2 11  ? 54.721  59.042  2.204   1.00 43.45  ? 212  DT    C C7    1 
ATOM   462   C  C6    . DT    B 2 11  ? 53.056  57.850  3.660   1.00 40.92  ? 212  DT    C C6    1 
ATOM   463   P  P     . DG    B 2 12  ? 51.522  54.773  9.113   1.00 49.01  ? 213  DG    C P     1 
ATOM   464   O  OP1   . DG    B 2 12  ? 50.421  54.518  10.106  1.00 45.68  ? 213  DG    C OP1   1 
ATOM   465   O  OP2   . DG    B 2 12  ? 52.937  55.054  9.533   1.00 48.63  ? 213  DG    C OP2   1 
ATOM   466   O  "O5'" . DG    B 2 12  ? 51.694  53.576  8.048   1.00 45.82  ? 213  DG    C "O5'" 1 
ATOM   467   C  "C5'" . DG    B 2 12  ? 50.532  52.811  7.612   1.00 45.85  ? 213  DG    C "C5'" 1 
ATOM   468   C  "C4'" . DG    B 2 12  ? 50.961  51.750  6.622   1.00 44.12  ? 213  DG    C "C4'" 1 
ATOM   469   O  "O4'" . DG    B 2 12  ? 51.552  52.414  5.487   1.00 39.95  ? 213  DG    C "O4'" 1 
ATOM   470   C  "C3'" . DG    B 2 12  ? 52.015  50.742  7.117   1.00 50.01  ? 213  DG    C "C3'" 1 
ATOM   471   O  "O3'" . DG    B 2 12  ? 51.889  49.461  6.487   1.00 56.06  ? 213  DG    C "O3'" 1 
ATOM   472   C  "C2'" . DG    B 2 12  ? 53.314  51.369  6.630   1.00 43.92  ? 213  DG    C "C2'" 1 
ATOM   473   C  "C1'" . DG    B 2 12  ? 52.853  51.861  5.271   1.00 45.56  ? 213  DG    C "C1'" 1 
ATOM   474   N  N9    . DG    B 2 12  ? 53.703  52.878  4.665   1.00 45.26  ? 213  DG    C N9    1 
ATOM   475   C  C8    . DG    B 2 12  ? 54.587  53.777  5.212   1.00 45.17  ? 213  DG    C C8    1 
ATOM   476   N  N7    . DG    B 2 12  ? 55.177  54.526  4.311   1.00 48.58  ? 213  DG    C N7    1 
ATOM   477   C  C5    . DG    B 2 12  ? 54.640  54.089  3.104   1.00 44.13  ? 213  DG    C C5    1 
ATOM   478   C  C6    . DG    B 2 12  ? 54.860  54.554  1.791   1.00 40.98  ? 213  DG    C C6    1 
ATOM   479   O  O6    . DG    B 2 12  ? 55.632  55.445  1.416   1.00 41.31  ? 213  DG    C O6    1 
ATOM   480   N  N1    . DG    B 2 12  ? 54.115  53.828  0.865   1.00 40.50  ? 213  DG    C N1    1 
ATOM   481   C  C2    . DG    B 2 12  ? 53.230  52.821  1.157   1.00 45.29  ? 213  DG    C C2    1 
ATOM   482   N  N2    . DG    B 2 12  ? 52.593  52.255  0.126   1.00 46.18  ? 213  DG    C N2    1 
ATOM   483   N  N3    . DG    B 2 12  ? 52.983  52.405  2.396   1.00 53.32  ? 213  DG    C N3    1 
ATOM   484   C  C4    . DG    B 2 12  ? 53.731  53.077  3.310   1.00 47.58  ? 213  DG    C C4    1 
ATOM   485   P  P     . DG    B 2 13  ? 51.429  48.273  7.467   1.00 60.12  ? 214  DG    C P     1 
ATOM   486   O  OP1   . DG    B 2 13  ? 50.169  48.631  8.209   1.00 51.09  ? 214  DG    C OP1   1 
ATOM   487   O  OP2   . DG    B 2 13  ? 52.652  47.842  8.236   1.00 57.00  ? 214  DG    C OP2   1 
ATOM   488   O  "O5'" . DG    B 2 13  ? 51.083  47.183  6.338   1.00 66.58  ? 214  DG    C "O5'" 1 
ATOM   489   C  "C5'" . DG    B 2 13  ? 50.031  47.471  5.370   1.00 69.53  ? 214  DG    C "C5'" 1 
ATOM   490   C  "C4'" . DG    B 2 13  ? 50.430  46.962  4.004   1.00 64.86  ? 214  DG    C "C4'" 1 
ATOM   491   O  "O4'" . DG    B 2 13  ? 51.282  47.918  3.328   1.00 59.67  ? 214  DG    C "O4'" 1 
ATOM   492   C  "C3'" . DG    B 2 13  ? 51.190  45.640  4.004   1.00 69.09  ? 214  DG    C "C3'" 1 
ATOM   493   O  "O3'" . DG    B 2 13  ? 50.693  44.897  2.890   1.00 76.44  ? 214  DG    C "O3'" 1 
ATOM   494   C  "C2'" . DG    B 2 13  ? 52.645  46.087  3.852   1.00 64.37  ? 214  DG    C "C2'" 1 
ATOM   495   C  "C1'" . DG    B 2 13  ? 52.502  47.293  2.936   1.00 60.44  ? 214  DG    C "C1'" 1 
ATOM   496   N  N9    . DG    B 2 13  ? 53.558  48.296  3.049   1.00 59.69  ? 214  DG    C N9    1 
ATOM   497   C  C8    . DG    B 2 13  ? 54.069  48.763  4.238   1.00 60.76  ? 214  DG    C C8    1 
ATOM   498   N  N7    . DG    B 2 13  ? 54.981  49.694  4.081   1.00 64.30  ? 214  DG    C N7    1 
ATOM   499   C  C5    . DG    B 2 13  ? 55.078  49.852  2.704   1.00 59.50  ? 214  DG    C C5    1 
ATOM   500   C  C6    . DG    B 2 13  ? 55.906  50.721  1.950   1.00 55.64  ? 214  DG    C C6    1 
ATOM   501   O  O6    . DG    B 2 13  ? 56.734  51.542  2.361   1.00 60.08  ? 214  DG    C O6    1 
ATOM   502   N  N1    . DG    B 2 13  ? 55.693  50.570  0.578   1.00 56.02  ? 214  DG    C N1    1 
ATOM   503   C  C2    . DG    B 2 13  ? 54.808  49.683  0.009   1.00 55.24  ? 214  DG    C C2    1 
ATOM   504   N  N2    . DG    B 2 13  ? 54.759  49.681  -1.331  1.00 51.58  ? 214  DG    C N2    1 
ATOM   505   N  N3    . DG    B 2 13  ? 54.017  48.867  0.715   1.00 52.73  ? 214  DG    C N3    1 
ATOM   506   C  C4    . DG    B 2 13  ? 54.196  49.008  2.053   1.00 58.63  ? 214  DG    C C4    1 
ATOM   507   P  P     . DT    B 2 14  ? 51.194  43.376  2.757   1.00 79.09  ? 215  DT    C P     1 
ATOM   508   O  OP1   . DT    B 2 14  ? 50.027  42.623  2.181   1.00 78.71  ? 215  DT    C OP1   1 
ATOM   509   O  OP2   . DT    B 2 14  ? 51.857  42.913  4.033   1.00 72.77  ? 215  DT    C OP2   1 
ATOM   510   O  "O5'" . DT    B 2 14  ? 52.311  43.549  1.613   1.00 70.77  ? 215  DT    C "O5'" 1 
ATOM   511   C  "C5'" . DT    B 2 14  ? 51.866  44.058  0.335   1.00 75.97  ? 215  DT    C "C5'" 1 
ATOM   512   C  "C4'" . DT    B 2 14  ? 53.031  44.170  -0.614  1.00 79.75  ? 215  DT    C "C4'" 1 
ATOM   513   O  "O4'" . DT    B 2 14  ? 53.877  45.275  -0.234  1.00 77.11  ? 215  DT    C "O4'" 1 
ATOM   514   C  "C3'" . DT    B 2 14  ? 53.936  42.939  -0.692  1.00 88.64  ? 215  DT    C "C3'" 1 
ATOM   515   O  "O3'" . DT    B 2 14  ? 54.138  42.653  -2.077  1.00 99.67  ? 215  DT    C "O3'" 1 
ATOM   516   C  "C2'" . DT    B 2 14  ? 55.232  43.392  -0.030  1.00 82.07  ? 215  DT    C "C2'" 1 
ATOM   517   C  "C1'" . DT    B 2 14  ? 55.233  44.875  -0.366  1.00 78.70  ? 215  DT    C "C1'" 1 
ATOM   518   N  N1    . DT    B 2 14  ? 56.018  45.734  0.537   1.00 71.98  ? 215  DT    C N1    1 
ATOM   519   C  C2    . DT    B 2 14  ? 56.836  46.702  -0.014  1.00 68.28  ? 215  DT    C C2    1 
ATOM   520   O  O2    . DT    B 2 14  ? 56.984  46.856  -1.223  1.00 61.79  ? 215  DT    C O2    1 
ATOM   521   N  N3    . DT    B 2 14  ? 57.505  47.470  0.908   1.00 65.96  ? 215  DT    C N3    1 
ATOM   522   C  C4    . DT    B 2 14  ? 57.438  47.374  2.287   1.00 67.45  ? 215  DT    C C4    1 
ATOM   523   O  O4    . DT    B 2 14  ? 58.108  48.147  2.981   1.00 69.79  ? 215  DT    C O4    1 
ATOM   524   C  C5    . DT    B 2 14  ? 56.556  46.341  2.796   1.00 72.89  ? 215  DT    C C5    1 
ATOM   525   C  C7    . DT    B 2 14  ? 56.404  46.158  4.281   1.00 73.65  ? 215  DT    C C7    1 
ATOM   526   C  C6    . DT    B 2 14  ? 55.896  45.585  1.905   1.00 73.85  ? 215  DT    C C6    1 
ATOM   527   P  P     . DC    B 2 15  ? 54.545  41.147  -2.467  1.00 100.19 ? 216  DC    C P     1 
ATOM   528   O  OP1   . DC    B 2 15  ? 53.554  40.699  -3.509  1.00 95.80  ? 216  DC    C OP1   1 
ATOM   529   O  OP2   . DC    B 2 15  ? 54.811  40.321  -1.228  1.00 76.72  ? 216  DC    C OP2   1 
ATOM   530   O  "O5'" . DC    B 2 15  ? 55.934  41.450  -3.217  1.00 91.37  ? 216  DC    C "O5'" 1 
ATOM   531   C  "C5'" . DC    B 2 15  ? 55.976  42.517  -4.205  1.00 102.79 ? 216  DC    C "C5'" 1 
ATOM   532   C  "C4'" . DC    B 2 15  ? 57.413  42.940  -4.375  1.00 115.17 ? 216  DC    C "C4'" 1 
ATOM   533   O  "O4'" . DC    B 2 15  ? 57.830  43.771  -3.262  1.00 112.26 ? 216  DC    C "O4'" 1 
ATOM   534   C  "C3'" . DC    B 2 15  ? 58.386  41.760  -4.418  1.00 123.83 ? 216  DC    C "C3'" 1 
ATOM   535   O  "O3'" . DC    B 2 15  ? 59.383  41.955  -5.421  1.00 143.19 ? 216  DC    C "O3'" 1 
ATOM   536   C  "C2'" . DC    B 2 15  ? 59.011  41.794  -3.032  1.00 115.71 ? 216  DC    C "C2'" 1 
ATOM   537   C  "C1'" . DC    B 2 15  ? 59.073  43.291  -2.792  1.00 106.94 ? 216  DC    C "C1'" 1 
ATOM   538   N  N1    . DC    B 2 15  ? 59.269  43.710  -1.380  1.00 89.64  ? 216  DC    C N1    1 
ATOM   539   C  C2    . DC    B 2 15  ? 59.987  44.886  -1.133  1.00 76.43  ? 216  DC    C C2    1 
ATOM   540   O  O2    . DC    B 2 15  ? 60.413  45.543  -2.097  1.00 69.62  ? 216  DC    C O2    1 
ATOM   541   N  N3    . DC    B 2 15  ? 60.186  45.273  0.152   1.00 74.00  ? 216  DC    C N3    1 
ATOM   542   C  C4    . DC    B 2 15  ? 59.716  44.534  1.168   1.00 77.59  ? 216  DC    C C4    1 
ATOM   543   N  N4    . DC    B 2 15  ? 59.951  44.960  2.397   1.00 77.73  ? 216  DC    C N4    1 
ATOM   544   C  C5    . DC    B 2 15  ? 58.994  43.329  0.939   1.00 80.10  ? 216  DC    C C5    1 
ATOM   545   C  C6    . DC    B 2 15  ? 58.802  42.956  -0.338  1.00 88.17  ? 216  DC    C C6    1 
HETATM 546   P  P     . OMG   B 2 16  ? 59.696  40.562  -6.194  1.00 150.53 ? 217  OMG   C P     1 
HETATM 547   O  OP1   . OMG   B 2 16  ? 58.615  40.321  -7.214  1.00 139.94 ? 217  OMG   C OP1   1 
HETATM 548   O  OP2   . OMG   B 2 16  ? 59.957  39.491  -5.159  1.00 131.07 ? 217  OMG   C OP2   1 
HETATM 549   O  "O5'" . OMG   B 2 16  ? 61.080  40.863  -6.965  1.00 146.71 ? 217  OMG   C "O5'" 1 
HETATM 550   C  "C5'" . OMG   B 2 16  ? 61.441  42.222  -7.361  1.00 144.46 ? 217  OMG   C "C5'" 1 
HETATM 551   C  "C4'" . OMG   B 2 16  ? 62.873  42.506  -6.965  1.00 141.34 ? 217  OMG   C "C4'" 1 
HETATM 552   O  "O4'" . OMG   B 2 16  ? 62.924  42.894  -5.564  1.00 140.54 ? 217  OMG   C "O4'" 1 
HETATM 553   C  "C3'" . OMG   B 2 16  ? 63.861  41.337  -7.100  1.00 136.66 ? 217  OMG   C "C3'" 1 
HETATM 554   O  "O3'" . OMG   B 2 16  ? 65.116  41.838  -7.542  1.00 129.78 ? 217  OMG   C "O3'" 1 
HETATM 555   C  "C2'" . OMG   B 2 16  ? 63.877  40.748  -5.678  1.00 137.69 ? 217  OMG   C "C2'" 1 
HETATM 556   O  "O2'" . OMG   B 2 16  ? 65.039  39.975  -5.366  1.00 122.19 ? 217  OMG   C "O2'" 1 
HETATM 557   C  CM2   . OMG   B 2 16  ? 64.753  38.678  -4.837  1.00 106.60 ? 217  OMG   C CM2   1 
HETATM 558   C  "C1'" . OMG   B 2 16  ? 63.796  42.038  -4.858  1.00 135.91 ? 217  OMG   C "C1'" 1 
HETATM 559   N  N9    . OMG   B 2 16  ? 63.289  41.855  -3.496  1.00 130.87 ? 217  OMG   C N9    1 
HETATM 560   C  C8    . OMG   B 2 16  ? 62.494  40.843  -3.012  1.00 125.50 ? 217  OMG   C C8    1 
HETATM 561   N  N7    . OMG   B 2 16  ? 62.220  40.958  -1.733  1.00 119.65 ? 217  OMG   C N7    1 
HETATM 562   C  C5    . OMG   B 2 16  ? 62.876  42.120  -1.344  1.00 118.51 ? 217  OMG   C C5    1 
HETATM 563   C  C6    . OMG   B 2 16  ? 62.945  42.756  -0.073  1.00 109.99 ? 217  OMG   C C6    1 
HETATM 564   O  O6    . OMG   B 2 16  ? 62.425  42.412  1.002   1.00 95.24  ? 217  OMG   C O6    1 
HETATM 565   N  N1    . OMG   B 2 16  ? 63.725  43.914  -0.132  1.00 106.75 ? 217  OMG   C N1    1 
HETATM 566   C  C2    . OMG   B 2 16  ? 64.356  44.400  -1.255  1.00 101.64 ? 217  OMG   C C2    1 
HETATM 567   N  N2    . OMG   B 2 16  ? 65.067  45.528  -1.115  1.00 93.81  ? 217  OMG   C N2    1 
HETATM 568   N  N3    . OMG   B 2 16  ? 64.289  43.809  -2.449  1.00 107.89 ? 217  OMG   C N3    1 
HETATM 569   C  C4    . OMG   B 2 16  ? 63.537  42.680  -2.421  1.00 120.85 ? 217  OMG   C C4    1 
ATOM   570   N  N     . GLU   C 3 3   ? 69.316  63.762  -43.335 1.00 107.47 ? 296  GLU   A N     1 
ATOM   571   C  CA    . GLU   C 3 3   ? 69.457  64.811  -42.289 1.00 101.53 ? 296  GLU   A CA    1 
ATOM   572   C  C     . GLU   C 3 3   ? 70.078  66.057  -42.911 1.00 95.79  ? 296  GLU   A C     1 
ATOM   573   O  O     . GLU   C 3 3   ? 71.270  66.074  -43.214 1.00 97.82  ? 296  GLU   A O     1 
ATOM   574   C  CB    . GLU   C 3 3   ? 70.312  64.322  -41.121 1.00 104.50 ? 296  GLU   A CB    1 
ATOM   575   C  CG    . GLU   C 3 3   ? 69.620  63.280  -40.271 1.00 110.68 ? 296  GLU   A CG    1 
ATOM   576   C  CD    . GLU   C 3 3   ? 70.474  62.720  -39.147 1.00 115.97 ? 296  GLU   A CD    1 
ATOM   577   O  OE1   . GLU   C 3 3   ? 71.622  63.179  -38.990 1.00 109.20 ? 296  GLU   A OE1   1 
ATOM   578   O  OE2   . GLU   C 3 3   ? 69.993  61.817  -38.435 1.00 119.52 ? 296  GLU   A OE2   1 
ATOM   579   N  N     . ALA   C 3 4   ? 69.249  67.095  -43.073 1.00 90.98  ? 297  ALA   A N     1 
ATOM   580   C  CA    . ALA   C 3 4   ? 69.667  68.356  -43.664 1.00 90.83  ? 297  ALA   A CA    1 
ATOM   581   C  C     . ALA   C 3 4   ? 70.103  69.328  -42.563 1.00 92.98  ? 297  ALA   A C     1 
ATOM   582   O  O     . ALA   C 3 4   ? 70.023  69.017  -41.373 1.00 76.99  ? 297  ALA   A O     1 
ATOM   583   C  CB    . ALA   C 3 4   ? 68.549  68.916  -44.512 1.00 90.50  ? 297  ALA   A CB    1 
ATOM   584   N  N     . PRO   C 3 5   ? 70.612  70.531  -42.919 1.00 102.49 ? 298  PRO   A N     1 
ATOM   585   C  CA    . PRO   C 3 5   ? 71.172  71.454  -41.931 1.00 98.64  ? 298  PRO   A CA    1 
ATOM   586   C  C     . PRO   C 3 5   ? 70.181  72.506  -41.431 1.00 89.90  ? 298  PRO   A C     1 
ATOM   587   O  O     . PRO   C 3 5   ? 69.299  72.943  -42.177 1.00 84.29  ? 298  PRO   A O     1 
ATOM   588   C  CB    . PRO   C 3 5   ? 72.307  72.085  -42.758 1.00 101.56 ? 298  PRO   A CB    1 
ATOM   589   C  CG    . PRO   C 3 5   ? 71.736  72.184  -44.173 1.00 102.74 ? 298  PRO   A CG    1 
ATOM   590   C  CD    . PRO   C 3 5   ? 70.724  71.060  -44.292 1.00 102.65 ? 298  PRO   A CD    1 
ATOM   591   N  N     . TRP   C 3 6   ? 70.346  72.916  -40.165 1.00 79.83  ? 299  TRP   A N     1 
ATOM   592   C  CA    . TRP   C 3 6   ? 69.621  74.058  -39.630 1.00 78.34  ? 299  TRP   A CA    1 
ATOM   593   C  C     . TRP   C 3 6   ? 69.953  75.293  -40.473 1.00 75.29  ? 299  TRP   A C     1 
ATOM   594   O  O     . TRP   C 3 6   ? 71.094  75.427  -40.898 1.00 74.99  ? 299  TRP   A O     1 
ATOM   595   C  CB    . TRP   C 3 6   ? 69.971  74.272  -38.146 1.00 80.15  ? 299  TRP   A CB    1 
ATOM   596   C  CG    . TRP   C 3 6   ? 68.928  75.065  -37.423 1.00 80.55  ? 299  TRP   A CG    1 
ATOM   597   C  CD1   . TRP   C 3 6   ? 68.907  76.414  -37.212 1.00 77.91  ? 299  TRP   A CD1   1 
ATOM   598   C  CD2   . TRP   C 3 6   ? 67.714  74.547  -36.850 1.00 77.11  ? 299  TRP   A CD2   1 
ATOM   599   N  NE1   . TRP   C 3 6   ? 67.759  76.770  -36.557 1.00 81.62  ? 299  TRP   A NE1   1 
ATOM   600   C  CE2   . TRP   C 3 6   ? 67.009  75.648  -36.320 1.00 74.48  ? 299  TRP   A CE2   1 
ATOM   601   C  CE3   . TRP   C 3 6   ? 67.154  73.267  -36.736 1.00 76.65  ? 299  TRP   A CE3   1 
ATOM   602   C  CZ2   . TRP   C 3 6   ? 65.779  75.503  -35.680 1.00 71.36  ? 299  TRP   A CZ2   1 
ATOM   603   C  CZ3   . TRP   C 3 6   ? 65.940  73.124  -36.099 1.00 71.01  ? 299  TRP   A CZ3   1 
ATOM   604   C  CH2   . TRP   C 3 6   ? 65.268  74.229  -35.573 1.00 70.13  ? 299  TRP   A CH2   1 
ATOM   605   N  N     . PRO   C 3 7   ? 69.024  76.245  -40.751 1.00 82.49  ? 300  PRO   A N     1 
ATOM   606   C  CA    . PRO   C 3 7   ? 67.642  76.204  -40.274 1.00 79.84  ? 300  PRO   A CA    1 
ATOM   607   C  C     . PRO   C 3 7   ? 66.723  75.393  -41.184 1.00 77.36  ? 300  PRO   A C     1 
ATOM   608   O  O     . PRO   C 3 7   ? 67.062  75.118  -42.334 1.00 76.11  ? 300  PRO   A O     1 
ATOM   609   C  CB    . PRO   C 3 7   ? 67.240  77.692  -40.271 1.00 79.07  ? 300  PRO   A CB    1 
ATOM   610   C  CG    . PRO   C 3 7   ? 68.017  78.295  -41.424 1.00 77.74  ? 300  PRO   A CG    1 
ATOM   611   C  CD    . PRO   C 3 7   ? 69.279  77.459  -41.550 1.00 80.36  ? 300  PRO   A CD    1 
ATOM   612   N  N     . PRO   C 3 8   ? 65.541  74.975  -40.672 1.00 79.21  ? 301  PRO   A N     1 
ATOM   613   C  CA    . PRO   C 3 8   ? 64.532  74.287  -41.480 1.00 72.30  ? 301  PRO   A CA    1 
ATOM   614   C  C     . PRO   C 3 8   ? 63.741  75.226  -42.385 1.00 67.90  ? 301  PRO   A C     1 
ATOM   615   O  O     . PRO   C 3 8   ? 63.714  76.433  -42.154 1.00 73.76  ? 301  PRO   A O     1 
ATOM   616   C  CB    . PRO   C 3 8   ? 63.597  73.698  -40.411 1.00 76.13  ? 301  PRO   A CB    1 
ATOM   617   C  CG    . PRO   C 3 8   ? 63.663  74.708  -39.283 1.00 76.28  ? 301  PRO   A CG    1 
ATOM   618   C  CD    . PRO   C 3 8   ? 65.115  75.138  -39.269 1.00 76.07  ? 301  PRO   A CD    1 
ATOM   619   N  N     . PRO   C 3 9   ? 63.038  74.696  -43.415 1.00 67.54  ? 302  PRO   A N     1 
ATOM   620   C  CA    . PRO   C 3 9   ? 62.173  75.521  -44.260 1.00 65.60  ? 302  PRO   A CA    1 
ATOM   621   C  C     . PRO   C 3 9   ? 60.959  75.959  -43.446 1.00 68.92  ? 302  PRO   A C     1 
ATOM   622   O  O     . PRO   C 3 9   ? 60.802  75.523  -42.312 1.00 66.12  ? 302  PRO   A O     1 
ATOM   623   C  CB    . PRO   C 3 9   ? 61.789  74.587  -45.420 1.00 67.17  ? 302  PRO   A CB    1 
ATOM   624   C  CG    . PRO   C 3 9   ? 61.926  73.176  -44.850 1.00 63.89  ? 302  PRO   A CG    1 
ATOM   625   C  CD    . PRO   C 3 9   ? 62.994  73.265  -43.779 1.00 65.51  ? 302  PRO   A CD    1 
ATOM   626   N  N     . GLU   C 3 10  ? 60.089  76.787  -44.036 1.00 74.80  ? 303  GLU   A N     1 
ATOM   627   C  CA    . GLU   C 3 10  ? 58.924  77.302  -43.333 1.00 72.89  ? 303  GLU   A CA    1 
ATOM   628   C  C     . GLU   C 3 10  ? 57.834  76.232  -43.217 1.00 73.40  ? 303  GLU   A C     1 
ATOM   629   O  O     . GLU   C 3 10  ? 57.757  75.313  -44.037 1.00 68.23  ? 303  GLU   A O     1 
ATOM   630   C  CB    . GLU   C 3 10  ? 58.407  78.564  -44.019 1.00 77.04  ? 303  GLU   A CB    1 
ATOM   631   C  CG    . GLU   C 3 10  ? 59.406  79.706  -43.950 1.00 84.29  ? 303  GLU   A CG    1 
ATOM   632   C  CD    . GLU   C 3 10  ? 58.862  80.954  -43.281 1.00 92.00  ? 303  GLU   A CD    1 
ATOM   633   O  OE1   . GLU   C 3 10  ? 57.829  81.485  -43.747 1.00 92.46  ? 303  GLU   A OE1   1 
ATOM   634   O  OE2   . GLU   C 3 10  ? 59.466  81.382  -42.279 1.00 96.39  ? 303  GLU   A OE2   1 
ATOM   635   N  N     . GLY   C 3 11  ? 57.016  76.358  -42.156 1.00 66.43  ? 304  GLY   A N     1 
ATOM   636   C  CA    . GLY   C 3 11  ? 55.950  75.414  -41.847 1.00 63.89  ? 304  GLY   A CA    1 
ATOM   637   C  C     . GLY   C 3 11  ? 56.475  74.052  -41.380 1.00 63.16  ? 304  GLY   A C     1 
ATOM   638   O  O     . GLY   C 3 11  ? 55.792  73.036  -41.507 1.00 59.94  ? 304  GLY   A O     1 
ATOM   639   N  N     . ALA   C 3 12  ? 57.706  74.027  -40.859 1.00 56.28  ? 305  ALA   A N     1 
ATOM   640   C  CA    . ALA   C 3 12  ? 58.265  72.803  -40.319 1.00 54.97  ? 305  ALA   A CA    1 
ATOM   641   C  C     . ALA   C 3 12  ? 57.681  72.569  -38.930 1.00 56.22  ? 305  ALA   A C     1 
ATOM   642   O  O     . ALA   C 3 12  ? 57.282  73.516  -38.256 1.00 57.75  ? 305  ALA   A O     1 
ATOM   643   C  CB    . ALA   C 3 12  ? 59.769  72.898  -40.266 1.00 51.76  ? 305  ALA   A CB    1 
ATOM   644   N  N     . PHE   C 3 13  ? 57.678  71.299  -38.513 1.00 50.98  ? 306  PHE   A N     1 
ATOM   645   C  CA    . PHE   C 3 13  ? 57.240  70.906  -37.191 1.00 47.51  ? 306  PHE   A CA    1 
ATOM   646   C  C     . PHE   C 3 13  ? 58.460  70.743  -36.297 1.00 48.10  ? 306  PHE   A C     1 
ATOM   647   O  O     . PHE   C 3 13  ? 59.451  70.170  -36.720 1.00 52.22  ? 306  PHE   A O     1 
ATOM   648   C  CB    . PHE   C 3 13  ? 56.460  69.590  -37.244 1.00 46.66  ? 306  PHE   A CB    1 
ATOM   649   C  CG    . PHE   C 3 13  ? 55.119  69.654  -37.933 1.00 45.80  ? 306  PHE   A CG    1 
ATOM   650   C  CD1   . PHE   C 3 13  ? 55.025  69.625  -39.318 1.00 46.87  ? 306  PHE   A CD1   1 
ATOM   651   C  CD2   . PHE   C 3 13  ? 53.949  69.734  -37.189 1.00 46.96  ? 306  PHE   A CD2   1 
ATOM   652   C  CE1   . PHE   C 3 13  ? 53.791  69.668  -39.949 1.00 47.05  ? 306  PHE   A CE1   1 
ATOM   653   C  CE2   . PHE   C 3 13  ? 52.716  69.789  -37.822 1.00 49.01  ? 306  PHE   A CE2   1 
ATOM   654   C  CZ    . PHE   C 3 13  ? 52.637  69.743  -39.200 1.00 48.75  ? 306  PHE   A CZ    1 
ATOM   655   N  N     . VAL   C 3 14  ? 58.342  71.189  -35.044 1.00 47.21  ? 307  VAL   A N     1 
ATOM   656   C  CA    . VAL   C 3 14  ? 59.453  71.212  -34.115 1.00 44.84  ? 307  VAL   A CA    1 
ATOM   657   C  C     . VAL   C 3 14  ? 59.365  70.011  -33.182 1.00 42.27  ? 307  VAL   A C     1 
ATOM   658   O  O     . VAL   C 3 14  ? 58.288  69.488  -32.898 1.00 49.22  ? 307  VAL   A O     1 
ATOM   659   C  CB    . VAL   C 3 14  ? 59.492  72.522  -33.303 1.00 49.77  ? 307  VAL   A CB    1 
ATOM   660   C  CG1   . VAL   C 3 14  ? 58.363  72.624  -32.291 1.00 48.42  ? 307  VAL   A CG1   1 
ATOM   661   C  CG2   . VAL   C 3 14  ? 60.824  72.687  -32.587 1.00 54.40  ? 307  VAL   A CG2   1 
ATOM   662   N  N     . GLY   C 3 15  ? 60.532  69.600  -32.692 1.00 38.89  ? 308  GLY   A N     1 
ATOM   663   C  CA    . GLY   C 3 15  ? 60.635  68.669  -31.589 1.00 38.44  ? 308  GLY   A CA    1 
ATOM   664   C  C     . GLY   C 3 15  ? 61.716  69.163  -30.643 1.00 41.83  ? 308  GLY   A C     1 
ATOM   665   O  O     . GLY   C 3 15  ? 62.616  69.887  -31.065 1.00 45.58  ? 308  GLY   A O     1 
ATOM   666   N  N     . PHE   C 3 16  ? 61.637  68.770  -29.372 1.00 41.66  ? 309  PHE   A N     1 
ATOM   667   C  CA    . PHE   C 3 16  ? 62.559  69.328  -28.402 1.00 40.73  ? 309  PHE   A CA    1 
ATOM   668   C  C     . PHE   C 3 16  ? 62.595  68.421  -27.185 1.00 41.70  ? 309  PHE   A C     1 
ATOM   669   O  O     . PHE   C 3 16  ? 61.701  67.582  -27.019 1.00 44.61  ? 309  PHE   A O     1 
ATOM   670   C  CB    . PHE   C 3 16  ? 62.161  70.766  -28.051 1.00 40.55  ? 309  PHE   A CB    1 
ATOM   671   C  CG    . PHE   C 3 16  ? 60.784  70.890  -27.448 1.00 41.32  ? 309  PHE   A CG    1 
ATOM   672   C  CD1   . PHE   C 3 16  ? 59.659  70.978  -28.250 1.00 41.29  ? 309  PHE   A CD1   1 
ATOM   673   C  CD2   . PHE   C 3 16  ? 60.608  70.868  -26.074 1.00 43.64  ? 309  PHE   A CD2   1 
ATOM   674   C  CE1   . PHE   C 3 16  ? 58.394  71.069  -27.689 1.00 40.86  ? 309  PHE   A CE1   1 
ATOM   675   C  CE2   . PHE   C 3 16  ? 59.341  70.960  -25.517 1.00 44.75  ? 309  PHE   A CE2   1 
ATOM   676   C  CZ    . PHE   C 3 16  ? 58.236  71.059  -26.327 1.00 40.52  ? 309  PHE   A CZ    1 
ATOM   677   N  N     . VAL   C 3 17  ? 63.675  68.572  -26.393 1.00 39.85  ? 310  VAL   A N     1 
ATOM   678   C  CA    . VAL   C 3 17  ? 63.822  67.852  -25.143 1.00 39.57  ? 310  VAL   A CA    1 
ATOM   679   C  C     . VAL   C 3 17  ? 64.152  68.860  -24.049 1.00 41.17  ? 310  VAL   A C     1 
ATOM   680   O  O     . VAL   C 3 17  ? 64.975  69.740  -24.258 1.00 39.28  ? 310  VAL   A O     1 
ATOM   681   C  CB    . VAL   C 3 17  ? 64.879  66.732  -25.239 1.00 41.23  ? 310  VAL   A CB    1 
ATOM   682   C  CG1   . VAL   C 3 17  ? 64.908  65.877  -23.982 1.00 43.98  ? 310  VAL   A CG1   1 
ATOM   683   C  CG2   . VAL   C 3 17  ? 64.651  65.853  -26.457 1.00 46.15  ? 310  VAL   A CG2   1 
ATOM   684   N  N     . LEU   C 3 18  ? 63.500  68.690  -22.890 1.00 45.28  ? 311  LEU   A N     1 
ATOM   685   C  CA    . LEU   C 3 18  ? 63.691  69.515  -21.707 1.00 41.77  ? 311  LEU   A CA    1 
ATOM   686   C  C     . LEU   C 3 18  ? 64.350  68.671  -20.623 1.00 42.85  ? 311  LEU   A C     1 
ATOM   687   O  O     . LEU   C 3 18  ? 64.082  67.475  -20.552 1.00 44.34  ? 311  LEU   A O     1 
ATOM   688   C  CB    . LEU   C 3 18  ? 62.320  69.960  -21.196 1.00 43.63  ? 311  LEU   A CB    1 
ATOM   689   C  CG    . LEU   C 3 18  ? 61.476  70.831  -22.121 1.00 43.74  ? 311  LEU   A CG    1 
ATOM   690   C  CD1   . LEU   C 3 18  ? 60.255  71.317  -21.354 1.00 42.07  ? 311  LEU   A CD1   1 
ATOM   691   C  CD2   . LEU   C 3 18  ? 62.284  72.002  -22.690 1.00 40.78  ? 311  LEU   A CD2   1 
ATOM   692   N  N     . SER   C 3 19  ? 65.153  69.297  -19.749 1.00 44.32  ? 312  SER   A N     1 
ATOM   693   C  CA    . SER   C 3 19  ? 65.736  68.590  -18.616 1.00 45.85  ? 312  SER   A CA    1 
ATOM   694   C  C     . SER   C 3 19  ? 64.640  68.082  -17.679 1.00 47.86  ? 312  SER   A C     1 
ATOM   695   O  O     . SER   C 3 19  ? 64.880  67.151  -16.913 1.00 48.55  ? 312  SER   A O     1 
ATOM   696   C  CB    . SER   C 3 19  ? 66.729  69.451  -17.868 1.00 47.70  ? 312  SER   A CB    1 
ATOM   697   O  OG    . SER   C 3 19  ? 66.113  70.622  -17.337 1.00 46.25  ? 312  SER   A OG    1 
ATOM   698   N  N     . ARG   C 3 20  ? 63.437  68.684  -17.750 1.00 49.08  ? 313  ARG   A N     1 
ATOM   699   C  CA    . ARG   C 3 20  ? 62.344  68.346  -16.845 1.00 47.20  ? 313  ARG   A CA    1 
ATOM   700   C  C     . ARG   C 3 20  ? 61.002  68.855  -17.385 1.00 43.07  ? 313  ARG   A C     1 
ATOM   701   O  O     . ARG   C 3 20  ? 60.960  69.585  -18.364 1.00 43.73  ? 313  ARG   A O     1 
ATOM   702   C  CB    . ARG   C 3 20  ? 62.661  68.922  -15.460 1.00 48.98  ? 313  ARG   A CB    1 
ATOM   703   C  CG    . ARG   C 3 20  ? 63.058  70.392  -15.489 1.00 49.28  ? 313  ARG   A CG    1 
ATOM   704   C  CD    . ARG   C 3 20  ? 63.505  70.931  -14.145 1.00 49.55  ? 313  ARG   A CD    1 
ATOM   705   N  NE    . ARG   C 3 20  ? 62.443  70.987  -13.157 1.00 49.88  ? 313  ARG   A NE    1 
ATOM   706   C  CZ    . ARG   C 3 20  ? 62.591  71.474  -11.935 1.00 50.68  ? 313  ARG   A CZ    1 
ATOM   707   N  NH1   . ARG   C 3 20  ? 63.715  72.083  -11.607 1.00 50.95  ? 313  ARG   A NH1   1 
ATOM   708   N  NH2   . ARG   C 3 20  ? 61.621  71.355  -11.048 1.00 49.89  ? 313  ARG   A NH2   1 
ATOM   709   N  N     . LYS   C 3 21  ? 59.918  68.420  -16.727 1.00 46.13  ? 314  LYS   A N     1 
ATOM   710   C  CA    . LYS   C 3 21  ? 58.521  68.694  -17.055 1.00 46.87  ? 314  LYS   A CA    1 
ATOM   711   C  C     . LYS   C 3 21  ? 58.218  70.181  -17.229 1.00 44.53  ? 314  LYS   A C     1 
ATOM   712   O  O     . LYS   C 3 21  ? 57.645  70.583  -18.240 1.00 45.68  ? 314  LYS   A O     1 
ATOM   713   C  CB    . LYS   C 3 21  ? 57.635  68.301  -15.862 1.00 50.92  ? 314  LYS   A CB    1 
ATOM   714   C  CG    . LYS   C 3 21  ? 57.237  66.841  -15.743 1.00 55.44  ? 314  LYS   A CG    1 
ATOM   715   C  CD    . LYS   C 3 21  ? 56.940  66.399  -14.311 1.00 55.32  ? 314  LYS   A CD    1 
ATOM   716   C  CE    . LYS   C 3 21  ? 56.080  67.347  -13.510 1.00 56.20  ? 314  LYS   A CE    1 
ATOM   717   N  NZ    . LYS   C 3 21  ? 55.757  66.754  -12.186 1.00 56.81  ? 314  LYS   A NZ    1 
ATOM   718   N  N     . GLU   C 3 22  ? 58.535  70.942  -16.170 1.00 38.90  ? 315  GLU   A N     1 
ATOM   719   C  CA    . GLU   C 3 22  ? 58.108  72.310  -15.962 1.00 39.31  ? 315  GLU   A CA    1 
ATOM   720   C  C     . GLU   C 3 22  ? 58.899  73.227  -16.876 1.00 39.52  ? 315  GLU   A C     1 
ATOM   721   O  O     . GLU   C 3 22  ? 60.078  73.440  -16.630 1.00 40.49  ? 315  GLU   A O     1 
ATOM   722   C  CB    . GLU   C 3 22  ? 58.373  72.759  -14.521 1.00 43.90  ? 315  GLU   A CB    1 
ATOM   723   C  CG    . GLU   C 3 22  ? 57.813  71.828  -13.455 1.00 47.84  ? 315  GLU   A CG    1 
ATOM   724   C  CD    . GLU   C 3 22  ? 58.780  70.780  -12.924 1.00 53.94  ? 315  GLU   A CD    1 
ATOM   725   O  OE1   . GLU   C 3 22  ? 59.644  70.306  -13.700 1.00 50.97  ? 315  GLU   A OE1   1 
ATOM   726   O  OE2   . GLU   C 3 22  ? 58.636  70.401  -11.747 1.00 58.01  ? 315  GLU   A OE2   1 
ATOM   727   N  N     . PRO   C 3 23  ? 58.298  73.809  -17.941 1.00 44.20  ? 316  PRO   A N     1 
ATOM   728   C  CA    . PRO   C 3 23  ? 59.051  74.626  -18.894 1.00 42.93  ? 316  PRO   A CA    1 
ATOM   729   C  C     . PRO   C 3 23  ? 59.730  75.854  -18.295 1.00 43.03  ? 316  PRO   A C     1 
ATOM   730   O  O     . PRO   C 3 23  ? 60.706  76.346  -18.853 1.00 43.33  ? 316  PRO   A O     1 
ATOM   731   C  CB    . PRO   C 3 23  ? 58.010  75.100  -19.919 1.00 42.58  ? 316  PRO   A CB    1 
ATOM   732   C  CG    . PRO   C 3 23  ? 56.874  74.125  -19.777 1.00 44.24  ? 316  PRO   A CG    1 
ATOM   733   C  CD    . PRO   C 3 23  ? 56.887  73.672  -18.332 1.00 43.76  ? 316  PRO   A CD    1 
ATOM   734   N  N     . MET   C 3 24  ? 59.212  76.365  -17.176 1.00 41.90  ? 317  MET   A N     1 
ATOM   735   C  CA    . MET   C 3 24  ? 59.786  77.579  -16.612 1.00 42.81  ? 317  MET   A CA    1 
ATOM   736   C  C     . MET   C 3 24  ? 61.095  77.256  -15.898 1.00 43.86  ? 317  MET   A C     1 
ATOM   737   O  O     . MET   C 3 24  ? 61.943  78.125  -15.760 1.00 45.23  ? 317  MET   A O     1 
ATOM   738   C  CB    . MET   C 3 24  ? 58.829  78.242  -15.617 1.00 42.42  ? 317  MET   A CB    1 
ATOM   739   C  CG    . MET   C 3 24  ? 57.762  79.048  -16.307 1.00 41.85  ? 317  MET   A CG    1 
ATOM   740   S  SD    . MET   C 3 24  ? 58.438  80.373  -17.319 1.00 35.88  ? 317  MET   A SD    1 
ATOM   741   C  CE    . MET   C 3 24  ? 59.141  81.374  -16.003 1.00 35.73  ? 317  MET   A CE    1 
ATOM   742   N  N     . TRP   C 3 25  ? 61.236  76.007  -15.448 1.00 42.85  ? 318  TRP   A N     1 
ATOM   743   C  CA    . TRP   C 3 25  ? 62.401  75.566  -14.704 1.00 45.61  ? 318  TRP   A CA    1 
ATOM   744   C  C     . TRP   C 3 25  ? 63.356  74.746  -15.567 1.00 46.49  ? 318  TRP   A C     1 
ATOM   745   O  O     . TRP   C 3 25  ? 64.415  74.340  -15.108 1.00 54.07  ? 318  TRP   A O     1 
ATOM   746   C  CB    . TRP   C 3 25  ? 61.939  74.747  -13.502 1.00 46.80  ? 318  TRP   A CB    1 
ATOM   747   C  CG    . TRP   C 3 25  ? 61.277  75.576  -12.450 1.00 49.42  ? 318  TRP   A CG    1 
ATOM   748   C  CD1   . TRP   C 3 25  ? 59.945  75.636  -12.174 1.00 48.49  ? 318  TRP   A CD1   1 
ATOM   749   C  CD2   . TRP   C 3 25  ? 61.932  76.452  -11.512 1.00 51.82  ? 318  TRP   A CD2   1 
ATOM   750   N  NE1   . TRP   C 3 25  ? 59.722  76.510  -11.145 1.00 53.86  ? 318  TRP   A NE1   1 
ATOM   751   C  CE2   . TRP   C 3 25  ? 60.919  77.021  -10.709 1.00 53.05  ? 318  TRP   A CE2   1 
ATOM   752   C  CE3   . TRP   C 3 25  ? 63.266  76.812  -11.275 1.00 49.04  ? 318  TRP   A CE3   1 
ATOM   753   C  CZ2   . TRP   C 3 25  ? 61.199  77.915  -9.672  1.00 48.97  ? 318  TRP   A CZ2   1 
ATOM   754   C  CZ3   . TRP   C 3 25  ? 63.543  77.699  -10.254 1.00 50.62  ? 318  TRP   A CZ3   1 
ATOM   755   C  CH2   . TRP   C 3 25  ? 62.520  78.239  -9.466  1.00 49.03  ? 318  TRP   A CH2   1 
ATOM   756   N  N     . ALA   C 3 26  ? 62.978  74.470  -16.807 1.00 49.65  ? 319  ALA   A N     1 
ATOM   757   C  CA    . ALA   C 3 26  ? 63.660  73.429  -17.547 1.00 49.74  ? 319  ALA   A CA    1 
ATOM   758   C  C     . ALA   C 3 26  ? 64.803  74.030  -18.346 1.00 44.85  ? 319  ALA   A C     1 
ATOM   759   O  O     . ALA   C 3 26  ? 64.750  75.178  -18.781 1.00 44.45  ? 319  ALA   A O     1 
ATOM   760   C  CB    . ALA   C 3 26  ? 62.707  72.700  -18.463 1.00 51.86  ? 319  ALA   A CB    1 
ATOM   761   N  N     . ASP   C 3 27  ? 65.772  73.159  -18.606 1.00 44.90  ? 320  ASP   A N     1 
ATOM   762   C  CA    . ASP   C 3 27  ? 66.850  73.397  -19.541 1.00 47.47  ? 320  ASP   A CA    1 
ATOM   763   C  C     . ASP   C 3 27  ? 66.473  72.785  -20.891 1.00 43.99  ? 320  ASP   A C     1 
ATOM   764   O  O     . ASP   C 3 27  ? 66.003  71.649  -20.948 1.00 45.77  ? 320  ASP   A O     1 
ATOM   765   C  CB    . ASP   C 3 27  ? 68.110  72.780  -18.936 1.00 59.05  ? 320  ASP   A CB    1 
ATOM   766   C  CG    . ASP   C 3 27  ? 69.399  73.436  -19.362 1.00 64.65  ? 320  ASP   A CG    1 
ATOM   767   O  OD1   . ASP   C 3 27  ? 69.348  74.590  -19.833 1.00 78.77  ? 320  ASP   A OD1   1 
ATOM   768   O  OD2   . ASP   C 3 27  ? 70.435  72.770  -19.222 1.00 70.50  ? 320  ASP   A OD2   1 
ATOM   769   N  N     . LEU   C 3 28  ? 66.675  73.541  -21.973 1.00 40.60  ? 321  LEU   A N     1 
ATOM   770   C  CA    . LEU   C 3 28  ? 66.479  73.044  -23.322 1.00 39.65  ? 321  LEU   A CA    1 
ATOM   771   C  C     . LEU   C 3 28  ? 67.717  72.276  -23.798 1.00 45.58  ? 321  LEU   A C     1 
ATOM   772   O  O     . LEU   C 3 28  ? 68.674  72.885  -24.276 1.00 45.37  ? 321  LEU   A O     1 
ATOM   773   C  CB    . LEU   C 3 28  ? 66.206  74.245  -24.229 1.00 39.95  ? 321  LEU   A CB    1 
ATOM   774   C  CG    . LEU   C 3 28  ? 65.943  73.909  -25.692 1.00 41.78  ? 321  LEU   A CG    1 
ATOM   775   C  CD1   . LEU   C 3 28  ? 64.744  72.971  -25.823 1.00 41.04  ? 321  LEU   A CD1   1 
ATOM   776   C  CD2   . LEU   C 3 28  ? 65.735  75.180  -26.509 1.00 44.24  ? 321  LEU   A CD2   1 
ATOM   777   N  N     . LEU   C 3 29  ? 67.654  70.937  -23.715 1.00 47.03  ? 322  LEU   A N     1 
ATOM   778   C  CA    . LEU   C 3 29  ? 68.735  70.045  -24.108 1.00 47.78  ? 322  LEU   A CA    1 
ATOM   779   C  C     . LEU   C 3 29  ? 68.880  69.924  -25.629 1.00 50.52  ? 322  LEU   A C     1 
ATOM   780   O  O     . LEU   C 3 29  ? 69.992  69.727  -26.115 1.00 50.02  ? 322  LEU   A O     1 
ATOM   781   C  CB    . LEU   C 3 29  ? 68.482  68.659  -23.505 1.00 47.45  ? 322  LEU   A CB    1 
ATOM   782   C  CG    . LEU   C 3 29  ? 68.431  68.584  -21.977 1.00 50.45  ? 322  LEU   A CG    1 
ATOM   783   C  CD1   . LEU   C 3 29  ? 68.381  67.140  -21.504 1.00 48.30  ? 322  LEU   A CD1   1 
ATOM   784   C  CD2   . LEU   C 3 29  ? 69.624  69.298  -21.349 1.00 54.29  ? 322  LEU   A CD2   1 
ATOM   785   N  N     . ALA   C 3 30  ? 67.779  69.971  -26.391 1.00 53.37  ? 323  ALA   A N     1 
ATOM   786   C  CA    . ALA   C 3 30  ? 67.849  69.693  -27.823 1.00 47.94  ? 323  ALA   A CA    1 
ATOM   787   C  C     . ALA   C 3 30  ? 66.610  70.211  -28.548 1.00 45.24  ? 323  ALA   A C     1 
ATOM   788   O  O     . ALA   C 3 30  ? 65.523  70.230  -27.977 1.00 48.08  ? 323  ALA   A O     1 
ATOM   789   C  CB    . ALA   C 3 30  ? 68.008  68.203  -28.041 1.00 51.73  ? 323  ALA   A CB    1 
ATOM   790   N  N     . LEU   C 3 31  ? 66.797  70.590  -29.818 1.00 42.04  ? 324  LEU   A N     1 
ATOM   791   C  CA    . LEU   C 3 31  ? 65.754  71.119  -30.679 1.00 43.90  ? 324  LEU   A CA    1 
ATOM   792   C  C     . LEU   C 3 31  ? 65.988  70.612  -32.100 1.00 49.16  ? 324  LEU   A C     1 
ATOM   793   O  O     . LEU   C 3 31  ? 67.108  70.699  -32.604 1.00 52.32  ? 324  LEU   A O     1 
ATOM   794   C  CB    . LEU   C 3 31  ? 65.802  72.651  -30.664 1.00 43.21  ? 324  LEU   A CB    1 
ATOM   795   C  CG    . LEU   C 3 31  ? 64.724  73.357  -31.494 1.00 48.28  ? 324  LEU   A CG    1 
ATOM   796   C  CD1   . LEU   C 3 31  ? 63.407  73.415  -30.746 1.00 49.60  ? 324  LEU   A CD1   1 
ATOM   797   C  CD2   . LEU   C 3 31  ? 65.133  74.769  -31.889 1.00 50.74  ? 324  LEU   A CD2   1 
ATOM   798   N  N     . ALA   C 3 32  ? 64.921  70.136  -32.755 1.00 52.57  ? 325  ALA   A N     1 
ATOM   799   C  CA    . ALA   C 3 32  ? 64.973  69.785  -34.166 1.00 52.25  ? 325  ALA   A CA    1 
ATOM   800   C  C     . ALA   C 3 32  ? 63.684  70.236  -34.827 1.00 51.72  ? 325  ALA   A C     1 
ATOM   801   O  O     . ALA   C 3 32  ? 62.747  70.620  -34.137 1.00 55.81  ? 325  ALA   A O     1 
ATOM   802   C  CB    . ALA   C 3 32  ? 65.170  68.301  -34.337 1.00 54.52  ? 325  ALA   A CB    1 
ATOM   803   N  N     . ALA   C 3 33  ? 63.664  70.164  -36.161 1.00 52.68  ? 326  ALA   A N     1 
ATOM   804   C  CA    . ALA   C 3 33  ? 62.492  70.485  -36.954 1.00 51.16  ? 326  ALA   A CA    1 
ATOM   805   C  C     . ALA   C 3 33  ? 62.418  69.559  -38.169 1.00 56.05  ? 326  ALA   A C     1 
ATOM   806   O  O     . ALA   C 3 33  ? 63.448  69.108  -38.671 1.00 54.81  ? 326  ALA   A O     1 
ATOM   807   C  CB    . ALA   C 3 33  ? 62.536  71.934  -37.358 1.00 51.77  ? 326  ALA   A CB    1 
ATOM   808   N  N     . ALA   C 3 34  ? 61.188  69.274  -38.633 1.00 56.10  ? 327  ALA   A N     1 
ATOM   809   C  CA    . ALA   C 3 34  ? 60.969  68.316  -39.704 1.00 53.23  ? 327  ALA   A CA    1 
ATOM   810   C  C     . ALA   C 3 34  ? 59.988  68.880  -40.723 1.00 56.74  ? 327  ALA   A C     1 
ATOM   811   O  O     . ALA   C 3 34  ? 58.986  69.493  -40.358 1.00 64.15  ? 327  ALA   A O     1 
ATOM   812   C  CB    . ALA   C 3 34  ? 60.476  67.009  -39.138 1.00 55.79  ? 327  ALA   A CB    1 
ATOM   813   N  N     . ARG   C 3 35  ? 60.302  68.675  -42.006 1.00 54.48  ? 328  ARG   A N     1 
ATOM   814   C  CA    . ARG   C 3 35  ? 59.370  68.944  -43.084 1.00 55.65  ? 328  ARG   A CA    1 
ATOM   815   C  C     . ARG   C 3 35  ? 59.633  67.932  -44.195 1.00 59.17  ? 328  ARG   A C     1 
ATOM   816   O  O     . ARG   C 3 35  ? 60.785  67.564  -44.444 1.00 62.11  ? 328  ARG   A O     1 
ATOM   817   C  CB    . ARG   C 3 35  ? 59.511  70.388  -43.575 1.00 60.20  ? 328  ARG   A CB    1 
ATOM   818   C  CG    . ARG   C 3 35  ? 58.242  70.977  -44.170 1.00 69.23  ? 328  ARG   A CG    1 
ATOM   819   C  CD    . ARG   C 3 35  ? 58.261  71.252  -45.665 1.00 80.79  ? 328  ARG   A CD    1 
ATOM   820   N  NE    . ARG   C 3 35  ? 56.897  71.497  -46.113 1.00 90.87  ? 328  ARG   A NE    1 
ATOM   821   C  CZ    . ARG   C 3 35  ? 56.126  72.496  -45.688 1.00 98.30  ? 328  ARG   A CZ    1 
ATOM   822   N  NH1   . ARG   C 3 35  ? 54.995  72.230  -45.057 1.00 101.29 ? 328  ARG   A NH1   1 
ATOM   823   N  NH2   . ARG   C 3 35  ? 56.526  73.752  -45.815 1.00 106.48 ? 328  ARG   A NH2   1 
ATOM   824   N  N     . GLY   C 3 36  ? 58.547  67.476  -44.830 1.00 61.00  ? 329  GLY   A N     1 
ATOM   825   C  CA    . GLY   C 3 36  ? 58.587  66.433  -45.842 1.00 55.27  ? 329  GLY   A CA    1 
ATOM   826   C  C     . GLY   C 3 36  ? 59.474  65.253  -45.450 1.00 57.39  ? 329  GLY   A C     1 
ATOM   827   O  O     . GLY   C 3 36  ? 60.100  64.652  -46.313 1.00 62.36  ? 329  GLY   A O     1 
ATOM   828   N  N     . GLY   C 3 37  ? 59.534  64.911  -44.158 1.00 53.38  ? 330  GLY   A N     1 
ATOM   829   C  CA    . GLY   C 3 37  ? 60.265  63.733  -43.719 1.00 55.43  ? 330  GLY   A CA    1 
ATOM   830   C  C     . GLY   C 3 37  ? 61.731  64.004  -43.370 1.00 60.90  ? 330  GLY   A C     1 
ATOM   831   O  O     . GLY   C 3 37  ? 62.360  63.159  -42.729 1.00 61.23  ? 330  GLY   A O     1 
ATOM   832   N  N     . ARG   C 3 38  ? 62.257  65.174  -43.782 1.00 63.37  ? 331  ARG   A N     1 
ATOM   833   C  CA    . ARG   C 3 38  ? 63.633  65.579  -43.510 1.00 64.93  ? 331  ARG   A CA    1 
ATOM   834   C  C     . ARG   C 3 38  ? 63.761  66.167  -42.102 1.00 62.72  ? 331  ARG   A C     1 
ATOM   835   O  O     . ARG   C 3 38  ? 62.994  67.045  -41.707 1.00 60.41  ? 331  ARG   A O     1 
ATOM   836   C  CB    . ARG   C 3 38  ? 64.105  66.650  -44.500 1.00 73.07  ? 331  ARG   A CB    1 
ATOM   837   C  CG    . ARG   C 3 38  ? 64.343  66.161  -45.918 1.00 80.65  ? 331  ARG   A CG    1 
ATOM   838   C  CD    . ARG   C 3 38  ? 65.132  67.192  -46.707 1.00 89.17  ? 331  ARG   A CD    1 
ATOM   839   N  NE    . ARG   C 3 38  ? 65.329  66.799  -48.094 1.00 101.49 ? 331  ARG   A NE    1 
ATOM   840   C  CZ    . ARG   C 3 38  ? 64.425  66.928  -49.065 1.00 106.50 ? 331  ARG   A CZ    1 
ATOM   841   N  NH1   . ARG   C 3 38  ? 63.272  67.536  -48.832 1.00 97.47  ? 331  ARG   A NH1   1 
ATOM   842   N  NH2   . ARG   C 3 38  ? 64.683  66.453  -50.273 1.00 102.75 ? 331  ARG   A NH2   1 
ATOM   843   N  N     . VAL   C 3 39  ? 64.765  65.700  -41.357 1.00 59.02  ? 332  VAL   A N     1 
ATOM   844   C  CA    . VAL   C 3 39  ? 64.988  66.144  -39.992 1.00 62.17  ? 332  VAL   A CA    1 
ATOM   845   C  C     . VAL   C 3 39  ? 66.170  67.112  -39.979 1.00 65.80  ? 332  VAL   A C     1 
ATOM   846   O  O     . VAL   C 3 39  ? 67.268  66.741  -40.384 1.00 65.35  ? 332  VAL   A O     1 
ATOM   847   C  CB    . VAL   C 3 39  ? 65.230  64.936  -39.069 1.00 62.19  ? 332  VAL   A CB    1 
ATOM   848   C  CG1   . VAL   C 3 39  ? 65.435  65.367  -37.627 1.00 69.53  ? 332  VAL   A CG1   1 
ATOM   849   C  CG2   . VAL   C 3 39  ? 64.098  63.918  -39.175 1.00 65.69  ? 332  VAL   A CG2   1 
ATOM   850   N  N     . HIS   C 3 40  ? 65.926  68.352  -39.522 1.00 62.49  ? 333  HIS   A N     1 
ATOM   851   C  CA    . HIS   C 3 40  ? 66.961  69.368  -39.391 1.00 56.43  ? 333  HIS   A CA    1 
ATOM   852   C  C     . HIS   C 3 40  ? 67.295  69.560  -37.914 1.00 55.61  ? 333  HIS   A C     1 
ATOM   853   O  O     . HIS   C 3 40  ? 66.479  70.084  -37.166 1.00 59.47  ? 333  HIS   A O     1 
ATOM   854   C  CB    . HIS   C 3 40  ? 66.501  70.688  -40.021 1.00 56.39  ? 333  HIS   A CB    1 
ATOM   855   C  CG    . HIS   C 3 40  ? 65.943  70.587  -41.411 1.00 59.54  ? 333  HIS   A CG    1 
ATOM   856   N  ND1   . HIS   C 3 40  ? 66.421  71.312  -42.479 1.00 65.75  ? 333  HIS   A ND1   1 
ATOM   857   C  CD2   . HIS   C 3 40  ? 64.883  69.871  -41.879 1.00 62.41  ? 333  HIS   A CD2   1 
ATOM   858   C  CE1   . HIS   C 3 40  ? 65.702  71.038  -43.565 1.00 62.59  ? 333  HIS   A CE1   1 
ATOM   859   N  NE2   . HIS   C 3 40  ? 64.742  70.144  -43.215 1.00 66.46  ? 333  HIS   A NE2   1 
ATOM   860   N  N     . ARG   C 3 41  ? 68.489  69.127  -37.488 1.00 54.55  ? 334  ARG   A N     1 
ATOM   861   C  CA    . ARG   C 3 41  ? 68.887  69.236  -36.092 1.00 56.99  ? 334  ARG   A CA    1 
ATOM   862   C  C     . ARG   C 3 41  ? 69.638  70.550  -35.876 1.00 59.80  ? 334  ARG   A C     1 
ATOM   863   O  O     . ARG   C 3 41  ? 70.430  70.956  -36.718 1.00 66.00  ? 334  ARG   A O     1 
ATOM   864   C  CB    . ARG   C 3 41  ? 69.723  68.020  -35.687 1.00 58.21  ? 334  ARG   A CB    1 
ATOM   865   C  CG    . ARG   C 3 41  ? 68.932  66.720  -35.677 1.00 58.40  ? 334  ARG   A CG    1 
ATOM   866   C  CD    . ARG   C 3 41  ? 69.757  65.549  -35.185 1.00 61.06  ? 334  ARG   A CD    1 
ATOM   867   N  NE    . ARG   C 3 41  ? 68.950  64.422  -34.726 1.00 64.05  ? 334  ARG   A NE    1 
ATOM   868   C  CZ    . ARG   C 3 41  ? 68.293  63.577  -35.516 1.00 65.85  ? 334  ARG   A CZ    1 
ATOM   869   N  NH1   . ARG   C 3 41  ? 68.272  63.750  -36.828 1.00 58.22  ? 334  ARG   A NH1   1 
ATOM   870   N  NH2   . ARG   C 3 41  ? 67.656  62.550  -34.979 1.00 63.83  ? 334  ARG   A NH2   1 
ATOM   871   N  N     . ALA   C 3 42  ? 69.346  71.226  -34.756 1.00 65.89  ? 335  ALA   A N     1 
ATOM   872   C  CA    . ALA   C 3 42  ? 69.936  72.517  -34.431 1.00 64.70  ? 335  ALA   A CA    1 
ATOM   873   C  C     . ALA   C 3 42  ? 71.086  72.312  -33.449 1.00 66.25  ? 335  ALA   A C     1 
ATOM   874   O  O     . ALA   C 3 42  ? 70.862  71.748  -32.378 1.00 59.33  ? 335  ALA   A O     1 
ATOM   875   C  CB    . ALA   C 3 42  ? 68.894  73.431  -33.840 1.00 63.19  ? 335  ALA   A CB    1 
ATOM   876   N  N     . PRO   C 3 43  ? 72.326  72.761  -33.778 1.00 67.32  ? 336  PRO   A N     1 
ATOM   877   C  CA    . PRO   C 3 43  ? 73.488  72.568  -32.900 1.00 67.33  ? 336  PRO   A CA    1 
ATOM   878   C  C     . PRO   C 3 43  ? 73.484  73.443  -31.643 1.00 62.42  ? 336  PRO   A C     1 
ATOM   879   O  O     . PRO   C 3 43  ? 74.025  73.047  -30.608 1.00 51.71  ? 336  PRO   A O     1 
ATOM   880   C  CB    . PRO   C 3 43  ? 74.679  72.942  -33.800 1.00 70.37  ? 336  PRO   A CB    1 
ATOM   881   C  CG    . PRO   C 3 43  ? 74.101  73.951  -34.775 1.00 72.44  ? 336  PRO   A CG    1 
ATOM   882   C  CD    . PRO   C 3 43  ? 72.674  73.487  -35.016 1.00 72.21  ? 336  PRO   A CD    1 
ATOM   883   N  N     . GLU   C 3 44  ? 72.874  74.635  -31.738 1.00 61.47  ? 337  GLU   A N     1 
ATOM   884   C  CA    . GLU   C 3 44  ? 72.692  75.493  -30.574 1.00 67.45  ? 337  GLU   A CA    1 
ATOM   885   C  C     . GLU   C 3 44  ? 71.197  75.688  -30.302 1.00 58.47  ? 337  GLU   A C     1 
ATOM   886   O  O     . GLU   C 3 44  ? 70.567  76.602  -30.843 1.00 52.54  ? 337  GLU   A O     1 
ATOM   887   C  CB    . GLU   C 3 44  ? 73.439  76.807  -30.792 1.00 74.16  ? 337  GLU   A CB    1 
ATOM   888   C  CG    . GLU   C 3 44  ? 74.946  76.626  -30.847 1.00 75.24  ? 337  GLU   A CG    1 
ATOM   889   C  CD    . GLU   C 3 44  ? 75.703  77.911  -31.116 1.00 78.48  ? 337  GLU   A CD    1 
ATOM   890   O  OE1   . GLU   C 3 44  ? 75.564  78.456  -32.237 1.00 75.10  ? 337  GLU   A OE1   1 
ATOM   891   O  OE2   . GLU   C 3 44  ? 76.396  78.378  -30.189 1.00 79.59  ? 337  GLU   A OE2   1 
ATOM   892   N  N     . PRO   C 3 45  ? 70.591  74.849  -29.430 1.00 53.07  ? 338  PRO   A N     1 
ATOM   893   C  CA    . PRO   C 3 45  ? 69.129  74.827  -29.267 1.00 53.35  ? 338  PRO   A CA    1 
ATOM   894   C  C     . PRO   C 3 45  ? 68.526  76.211  -29.000 1.00 52.00  ? 338  PRO   A C     1 
ATOM   895   O  O     . PRO   C 3 45  ? 67.710  76.687  -29.794 1.00 49.17  ? 338  PRO   A O     1 
ATOM   896   C  CB    . PRO   C 3 45  ? 68.874  73.872  -28.089 1.00 53.19  ? 338  PRO   A CB    1 
ATOM   897   C  CG    . PRO   C 3 45  ? 70.184  73.096  -27.881 1.00 54.85  ? 338  PRO   A CG    1 
ATOM   898   C  CD    . PRO   C 3 45  ? 71.283  73.911  -28.529 1.00 52.13  ? 338  PRO   A CD    1 
ATOM   899   N  N     . TYR   C 3 46  ? 68.992  76.875  -27.924 1.00 48.22  ? 339  TYR   A N     1 
ATOM   900   C  CA    . TYR   C 3 46  ? 68.454  78.152  -27.469 1.00 48.49  ? 339  TYR   A CA    1 
ATOM   901   C  C     . TYR   C 3 46  ? 68.529  79.249  -28.536 1.00 51.45  ? 339  TYR   A C     1 
ATOM   902   O  O     . TYR   C 3 46  ? 67.656  80.111  -28.589 1.00 52.03  ? 339  TYR   A O     1 
ATOM   903   C  CB    . TYR   C 3 46  ? 69.185  78.628  -26.213 1.00 44.98  ? 339  TYR   A CB    1 
ATOM   904   C  CG    . TYR   C 3 46  ? 68.796  77.978  -24.903 1.00 41.08  ? 339  TYR   A CG    1 
ATOM   905   C  CD1   . TYR   C 3 46  ? 67.716  78.432  -24.161 1.00 43.30  ? 339  TYR   A CD1   1 
ATOM   906   C  CD2   . TYR   C 3 46  ? 69.532  76.935  -24.373 1.00 40.84  ? 339  TYR   A CD2   1 
ATOM   907   C  CE1   . TYR   C 3 46  ? 67.380  77.873  -22.935 1.00 41.83  ? 339  TYR   A CE1   1 
ATOM   908   C  CE2   . TYR   C 3 46  ? 69.199  76.348  -23.158 1.00 40.67  ? 339  TYR   A CE2   1 
ATOM   909   C  CZ    . TYR   C 3 46  ? 68.124  76.820  -22.431 1.00 40.92  ? 339  TYR   A CZ    1 
ATOM   910   O  OH    . TYR   C 3 46  ? 67.829  76.238  -21.218 1.00 42.69  ? 339  TYR   A OH    1 
ATOM   911   N  N     . LYS   C 3 47  ? 69.573  79.247  -29.371 1.00 59.41  ? 340  LYS   A N     1 
ATOM   912   C  CA    . LYS   C 3 47  ? 69.750  80.299  -30.367 1.00 64.10  ? 340  LYS   A CA    1 
ATOM   913   C  C     . LYS   C 3 47  ? 68.931  79.977  -31.609 1.00 59.52  ? 340  LYS   A C     1 
ATOM   914   O  O     . LYS   C 3 47  ? 68.563  80.876  -32.366 1.00 60.76  ? 340  LYS   A O     1 
ATOM   915   C  CB    . LYS   C 3 47  ? 71.228  80.461  -30.742 1.00 75.74  ? 340  LYS   A CB    1 
ATOM   916   C  CG    . LYS   C 3 47  ? 72.179  80.447  -29.552 1.00 84.59  ? 340  LYS   A CG    1 
ATOM   917   C  CD    . LYS   C 3 47  ? 73.476  81.187  -29.772 1.00 92.87  ? 340  LYS   A CD    1 
ATOM   918   C  CE    . LYS   C 3 47  ? 74.291  81.287  -28.497 1.00 96.94  ? 340  LYS   A CE    1 
ATOM   919   N  NZ    . LYS   C 3 47  ? 75.517  82.094  -28.691 1.00 98.03  ? 340  LYS   A NZ    1 
ATOM   920   N  N     . ALA   C 3 48  ? 68.679  78.678  -31.804 1.00 59.22  ? 341  ALA   A N     1 
ATOM   921   C  CA    . ALA   C 3 48  ? 67.929  78.167  -32.942 1.00 60.89  ? 341  ALA   A CA    1 
ATOM   922   C  C     . ALA   C 3 48  ? 66.440  78.516  -32.842 1.00 59.76  ? 341  ALA   A C     1 
ATOM   923   O  O     . ALA   C 3 48  ? 65.745  78.549  -33.864 1.00 50.30  ? 341  ALA   A O     1 
ATOM   924   C  CB    . ALA   C 3 48  ? 68.144  76.676  -33.027 1.00 63.16  ? 341  ALA   A CB    1 
ATOM   925   N  N     . LEU   C 3 49  ? 65.967  78.808  -31.616 1.00 53.67  ? 342  LEU   A N     1 
ATOM   926   C  CA    . LEU   C 3 49  ? 64.609  79.289  -31.399 1.00 51.86  ? 342  LEU   A CA    1 
ATOM   927   C  C     . LEU   C 3 49  ? 64.319  80.538  -32.233 1.00 52.66  ? 342  LEU   A C     1 
ATOM   928   O  O     . LEU   C 3 49  ? 63.182  80.728  -32.652 1.00 50.37  ? 342  LEU   A O     1 
ATOM   929   C  CB    . LEU   C 3 49  ? 64.412  79.573  -29.906 1.00 50.10  ? 342  LEU   A CB    1 
ATOM   930   C  CG    . LEU   C 3 49  ? 64.424  78.343  -29.000 1.00 51.19  ? 342  LEU   A CG    1 
ATOM   931   C  CD1   . LEU   C 3 49  ? 64.361  78.735  -27.529 1.00 47.72  ? 342  LEU   A CD1   1 
ATOM   932   C  CD2   . LEU   C 3 49  ? 63.271  77.404  -29.352 1.00 54.95  ? 342  LEU   A CD2   1 
ATOM   933   N  N     . ARG   C 3 50  ? 65.333  81.390  -32.457 1.00 60.79  ? 343  ARG   A N     1 
ATOM   934   C  CA    . ARG   C 3 50  ? 65.169  82.648  -33.182 1.00 62.98  ? 343  ARG   A CA    1 
ATOM   935   C  C     . ARG   C 3 50  ? 64.773  82.421  -34.640 1.00 57.71  ? 343  ARG   A C     1 
ATOM   936   O  O     . ARG   C 3 50  ? 64.244  83.334  -35.266 1.00 58.72  ? 343  ARG   A O     1 
ATOM   937   C  CB    . ARG   C 3 50  ? 66.460  83.477  -33.209 1.00 69.45  ? 343  ARG   A CB    1 
ATOM   938   C  CG    . ARG   C 3 50  ? 66.661  84.396  -32.016 1.00 73.96  ? 343  ARG   A CG    1 
ATOM   939   C  CD    . ARG   C 3 50  ? 66.913  83.603  -30.754 1.00 84.61  ? 343  ARG   A CD    1 
ATOM   940   N  NE    . ARG   C 3 50  ? 67.378  84.459  -29.674 1.00 93.70  ? 343  ARG   A NE    1 
ATOM   941   C  CZ    . ARG   C 3 50  ? 67.584  84.053  -28.428 1.00 99.09  ? 343  ARG   A CZ    1 
ATOM   942   N  NH1   . ARG   C 3 50  ? 67.205  82.846  -28.047 1.00 90.43  ? 343  ARG   A NH1   1 
ATOM   943   N  NH2   . ARG   C 3 50  ? 68.169  84.865  -27.565 1.00 107.27 ? 343  ARG   A NH2   1 
ATOM   944   N  N     . ASP   C 3 51  ? 65.061  81.230  -35.180 1.00 56.14  ? 344  ASP   A N     1 
ATOM   945   C  CA    . ASP   C 3 51  ? 64.886  80.967  -36.601 1.00 62.46  ? 344  ASP   A CA    1 
ATOM   946   C  C     . ASP   C 3 51  ? 63.445  80.559  -36.922 1.00 68.46  ? 344  ASP   A C     1 
ATOM   947   O  O     . ASP   C 3 51  ? 63.011  80.698  -38.066 1.00 65.55  ? 344  ASP   A O     1 
ATOM   948   C  CB    . ASP   C 3 51  ? 65.916  79.942  -37.080 1.00 63.83  ? 344  ASP   A CB    1 
ATOM   949   C  CG    . ASP   C 3 51  ? 67.346  80.424  -36.887 1.00 61.09  ? 344  ASP   A CG    1 
ATOM   950   O  OD1   . ASP   C 3 51  ? 67.617  81.575  -37.280 1.00 56.78  ? 344  ASP   A OD1   1 
ATOM   951   O  OD2   . ASP   C 3 51  ? 68.164  79.662  -36.315 1.00 56.06  ? 344  ASP   A OD2   1 
ATOM   952   N  N     . LEU   C 3 52  ? 62.703  80.096  -35.904 1.00 64.72  ? 345  LEU   A N     1 
ATOM   953   C  CA    . LEU   C 3 52  ? 61.324  79.658  -36.063 1.00 57.63  ? 345  LEU   A CA    1 
ATOM   954   C  C     . LEU   C 3 52  ? 60.390  80.854  -35.932 1.00 53.83  ? 345  LEU   A C     1 
ATOM   955   O  O     . LEU   C 3 52  ? 60.607  81.714  -35.082 1.00 55.33  ? 345  LEU   A O     1 
ATOM   956   C  CB    . LEU   C 3 52  ? 61.029  78.612  -34.982 1.00 52.29  ? 345  LEU   A CB    1 
ATOM   957   C  CG    . LEU   C 3 52  ? 61.948  77.397  -35.011 1.00 48.75  ? 345  LEU   A CG    1 
ATOM   958   C  CD1   . LEU   C 3 52  ? 61.689  76.466  -33.840 1.00 49.54  ? 345  LEU   A CD1   1 
ATOM   959   C  CD2   . LEU   C 3 52  ? 61.790  76.664  -36.332 1.00 51.85  ? 345  LEU   A CD2   1 
ATOM   960   N  N     . LYS   C 3 53  ? 59.335  80.877  -36.754 1.00 59.51  ? 346  LYS   A N     1 
ATOM   961   C  CA    . LYS   C 3 53  ? 58.287  81.888  -36.652 1.00 64.94  ? 346  LYS   A CA    1 
ATOM   962   C  C     . LYS   C 3 53  ? 57.223  81.499  -35.623 1.00 59.28  ? 346  LYS   A C     1 
ATOM   963   O  O     . LYS   C 3 53  ? 56.494  82.351  -35.114 1.00 55.53  ? 346  LYS   A O     1 
ATOM   964   C  CB    . LYS   C 3 53  ? 57.656  82.109  -38.026 1.00 71.93  ? 346  LYS   A CB    1 
ATOM   965   C  CG    . LYS   C 3 53  ? 58.641  82.648  -39.050 1.00 80.29  ? 346  LYS   A CG    1 
ATOM   966   C  CD    . LYS   C 3 53  ? 58.020  83.455  -40.168 1.00 87.21  ? 346  LYS   A CD    1 
ATOM   967   C  CE    . LYS   C 3 53  ? 59.055  84.290  -40.895 1.00 89.83  ? 346  LYS   A CE    1 
ATOM   968   N  NZ    . LYS   C 3 53  ? 58.483  84.965  -42.083 1.00 95.80  ? 346  LYS   A NZ    1 
ATOM   969   N  N     . GLU   C 3 54  ? 57.113  80.195  -35.351 1.00 56.28  ? 347  GLU   A N     1 
ATOM   970   C  CA    . GLU   C 3 54  ? 56.187  79.669  -34.363 1.00 50.44  ? 347  GLU   A CA    1 
ATOM   971   C  C     . GLU   C 3 54  ? 56.685  78.289  -33.962 1.00 47.27  ? 347  GLU   A C     1 
ATOM   972   O  O     . GLU   C 3 54  ? 57.443  77.672  -34.707 1.00 45.53  ? 347  GLU   A O     1 
ATOM   973   C  CB    . GLU   C 3 54  ? 54.752  79.601  -34.914 1.00 50.15  ? 347  GLU   A CB    1 
ATOM   974   C  CG    . GLU   C 3 54  ? 54.601  78.677  -36.112 1.00 55.21  ? 347  GLU   A CG    1 
ATOM   975   C  CD    . GLU   C 3 54  ? 53.218  78.527  -36.734 1.00 63.16  ? 347  GLU   A CD    1 
ATOM   976   O  OE1   . GLU   C 3 54  ? 52.211  78.980  -36.128 1.00 64.38  ? 347  GLU   A OE1   1 
ATOM   977   O  OE2   . GLU   C 3 54  ? 53.154  77.948  -37.842 1.00 65.15  ? 347  GLU   A OE2   1 
ATOM   978   N  N     . ALA   C 3 55  ? 56.226  77.803  -32.803 1.00 44.18  ? 348  ALA   A N     1 
ATOM   979   C  CA    . ALA   C 3 55  ? 56.366  76.402  -32.439 1.00 41.00  ? 348  ALA   A CA    1 
ATOM   980   C  C     . ALA   C 3 55  ? 55.138  75.600  -32.881 1.00 40.25  ? 348  ALA   A C     1 
ATOM   981   O  O     . ALA   C 3 55  ? 54.066  75.741  -32.302 1.00 42.36  ? 348  ALA   A O     1 
ATOM   982   C  CB    . ALA   C 3 55  ? 56.602  76.308  -30.948 1.00 40.94  ? 348  ALA   A CB    1 
ATOM   983   N  N     . ARG   C 3 56  ? 55.306  74.769  -33.923 1.00 46.17  ? 349  ARG   A N     1 
ATOM   984   C  CA    . ARG   C 3 56  ? 54.299  73.826  -34.393 1.00 44.81  ? 349  ARG   A CA    1 
ATOM   985   C  C     . ARG   C 3 56  ? 54.726  72.410  -34.036 1.00 46.49  ? 349  ARG   A C     1 
ATOM   986   O  O     . ARG   C 3 56  ? 55.729  71.927  -34.547 1.00 48.86  ? 349  ARG   A O     1 
ATOM   987   C  CB    . ARG   C 3 56  ? 54.189  73.744  -35.914 1.00 45.40  ? 349  ARG   A CB    1 
ATOM   988   C  CG    . ARG   C 3 56  ? 53.727  75.001  -36.619 1.00 53.36  ? 349  ARG   A CG    1 
ATOM   989   C  CD    . ARG   C 3 56  ? 53.621  74.717  -38.111 1.00 53.17  ? 349  ARG   A CD    1 
ATOM   990   N  NE    . ARG   C 3 56  ? 52.452  73.922  -38.442 1.00 53.00  ? 349  ARG   A NE    1 
ATOM   991   C  CZ    . ARG   C 3 56  ? 52.265  73.277  -39.591 1.00 55.76  ? 349  ARG   A CZ    1 
ATOM   992   N  NH1   . ARG   C 3 56  ? 53.275  73.054  -40.414 1.00 55.81  ? 349  ARG   A NH1   1 
ATOM   993   N  NH2   . ARG   C 3 56  ? 51.067  72.815  -39.898 1.00 53.47  ? 349  ARG   A NH2   1 
ATOM   994   N  N     . GLY   C 3 57  ? 53.945  71.715  -33.213 1.00 43.65  ? 350  GLY   A N     1 
ATOM   995   C  CA    . GLY   C 3 57  ? 54.227  70.316  -32.977 1.00 40.36  ? 350  GLY   A CA    1 
ATOM   996   C  C     . GLY   C 3 57  ? 53.793  69.901  -31.589 1.00 40.31  ? 350  GLY   A C     1 
ATOM   997   O  O     . GLY   C 3 57  ? 53.141  70.667  -30.881 1.00 40.76  ? 350  GLY   A O     1 
ATOM   998   N  N     . LEU   C 3 58  ? 54.179  68.678  -31.221 1.00 37.41  ? 351  LEU   A N     1 
ATOM   999   C  CA    . LEU   C 3 58  ? 53.749  68.123  -29.960 1.00 36.65  ? 351  LEU   A CA    1 
ATOM   1000  C  C     . LEU   C 3 58  ? 54.236  69.037  -28.834 1.00 40.33  ? 351  LEU   A C     1 
ATOM   1001  O  O     . LEU   C 3 58  ? 55.401  69.432  -28.812 1.00 37.09  ? 351  LEU   A O     1 
ATOM   1002  C  CB    . LEU   C 3 58  ? 54.295  66.706  -29.829 1.00 35.71  ? 351  LEU   A CB    1 
ATOM   1003  C  CG    . LEU   C 3 58  ? 53.683  65.678  -30.770 1.00 38.44  ? 351  LEU   A CG    1 
ATOM   1004  C  CD1   . LEU   C 3 58  ? 54.517  64.404  -30.753 1.00 41.64  ? 351  LEU   A CD1   1 
ATOM   1005  C  CD2   . LEU   C 3 58  ? 52.236  65.382  -30.396 1.00 39.85  ? 351  LEU   A CD2   1 
ATOM   1006  N  N     . LEU   C 3 59  ? 53.305  69.371  -27.932 1.00 37.15  ? 352  LEU   A N     1 
ATOM   1007  C  CA    . LEU   C 3 59  ? 53.562  70.148  -26.737 1.00 37.99  ? 352  LEU   A CA    1 
ATOM   1008  C  C     . LEU   C 3 59  ? 54.130  71.514  -27.107 1.00 34.39  ? 352  LEU   A C     1 
ATOM   1009  O  O     . LEU   C 3 59  ? 54.971  72.035  -26.399 1.00 32.49  ? 352  LEU   A O     1 
ATOM   1010  C  CB    . LEU   C 3 59  ? 54.503  69.360  -25.818 1.00 39.61  ? 352  LEU   A CB    1 
ATOM   1011  C  CG    . LEU   C 3 59  ? 54.037  67.958  -25.432 1.00 40.87  ? 352  LEU   A CG    1 
ATOM   1012  C  CD1   . LEU   C 3 59  ? 55.087  67.261  -24.545 1.00 39.31  ? 352  LEU   A CD1   1 
ATOM   1013  C  CD2   . LEU   C 3 59  ? 52.687  68.007  -24.727 1.00 41.67  ? 352  LEU   A CD2   1 
ATOM   1014  N  N     . ALA   C 3 60  ? 53.612  72.113  -28.188 1.00 34.22  ? 353  ALA   A N     1 
ATOM   1015  C  CA    . ALA   C 3 60  ? 54.112  73.384  -28.688 1.00 33.97  ? 353  ALA   A CA    1 
ATOM   1016  C  C     . ALA   C 3 60  ? 54.123  74.472  -27.605 1.00 37.16  ? 353  ALA   A C     1 
ATOM   1017  O  O     . ALA   C 3 60  ? 55.038  75.303  -27.565 1.00 37.98  ? 353  ALA   A O     1 
ATOM   1018  C  CB    . ALA   C 3 60  ? 53.288  73.813  -29.877 1.00 34.78  ? 353  ALA   A CB    1 
ATOM   1019  N  N     . LYS   C 3 61  ? 53.084  74.500  -26.761 1.00 34.79  ? 354  LYS   A N     1 
ATOM   1020  C  CA    . LYS   C 3 61  ? 52.951  75.539  -25.757 1.00 34.91  ? 354  LYS   A CA    1 
ATOM   1021  C  C     . LYS   C 3 61  ? 54.134  75.507  -24.786 1.00 32.98  ? 354  LYS   A C     1 
ATOM   1022  O  O     . LYS   C 3 61  ? 54.598  76.547  -24.346 1.00 35.38  ? 354  LYS   A O     1 
ATOM   1023  C  CB    . LYS   C 3 61  ? 51.625  75.371  -25.001 1.00 36.29  ? 354  LYS   A CB    1 
ATOM   1024  C  CG    . LYS   C 3 61  ? 51.424  76.326  -23.828 1.00 35.77  ? 354  LYS   A CG    1 
ATOM   1025  C  CD    . LYS   C 3 61  ? 50.534  75.788  -22.761 1.00 41.05  ? 354  LYS   A CD    1 
ATOM   1026  C  CE    . LYS   C 3 61  ? 51.216  74.706  -21.958 1.00 43.33  ? 354  LYS   A CE    1 
ATOM   1027  N  NZ    . LYS   C 3 61  ? 50.259  74.040  -21.056 1.00 46.59  ? 354  LYS   A NZ    1 
ATOM   1028  N  N     . ASP   C 3 62  ? 54.573  74.316  -24.388 1.00 34.83  ? 355  ASP   A N     1 
ATOM   1029  C  CA    . ASP   C 3 62  ? 55.646  74.174  -23.424 1.00 37.43  ? 355  ASP   A CA    1 
ATOM   1030  C  C     . ASP   C 3 62  ? 56.924  74.831  -23.933 1.00 40.62  ? 355  ASP   A C     1 
ATOM   1031  O  O     . ASP   C 3 62  ? 57.624  75.480  -23.158 1.00 40.47  ? 355  ASP   A O     1 
ATOM   1032  C  CB    . ASP   C 3 62  ? 55.868  72.704  -23.088 1.00 42.49  ? 355  ASP   A CB    1 
ATOM   1033  C  CG    . ASP   C 3 62  ? 54.792  72.148  -22.171 1.00 44.94  ? 355  ASP   A CG    1 
ATOM   1034  O  OD1   . ASP   C 3 62  ? 54.017  72.975  -21.610 1.00 43.30  ? 355  ASP   A OD1   1 
ATOM   1035  O  OD2   . ASP   C 3 62  ? 54.735  70.901  -22.030 1.00 44.23  ? 355  ASP   A OD2   1 
ATOM   1036  N  N     . LEU   C 3 63  ? 57.213  74.682  -25.231 1.00 38.69  ? 356  LEU   A N     1 
ATOM   1037  C  CA    . LEU   C 3 63  ? 58.422  75.256  -25.794 1.00 38.57  ? 356  LEU   A CA    1 
ATOM   1038  C  C     . LEU   C 3 63  ? 58.272  76.767  -25.859 1.00 38.88  ? 356  LEU   A C     1 
ATOM   1039  O  O     . LEU   C 3 63  ? 59.214  77.503  -25.593 1.00 43.99  ? 356  LEU   A O     1 
ATOM   1040  C  CB    . LEU   C 3 63  ? 58.684  74.700  -27.195 1.00 35.82  ? 356  LEU   A CB    1 
ATOM   1041  C  CG    . LEU   C 3 63  ? 59.949  75.238  -27.872 1.00 36.96  ? 356  LEU   A CG    1 
ATOM   1042  C  CD1   . LEU   C 3 63  ? 61.200  74.856  -27.096 1.00 34.54  ? 356  LEU   A CD1   1 
ATOM   1043  C  CD2   . LEU   C 3 63  ? 60.054  74.747  -29.312 1.00 36.51  ? 356  LEU   A CD2   1 
ATOM   1044  N  N     . SER   C 3 64  ? 57.078  77.204  -26.246 1.00 38.91  ? 357  SER   A N     1 
ATOM   1045  C  CA    . SER   C 3 64  ? 56.757  78.615  -26.319 1.00 38.03  ? 357  SER   A CA    1 
ATOM   1046  C  C     . SER   C 3 64  ? 56.936  79.286  -24.952 1.00 38.73  ? 357  SER   A C     1 
ATOM   1047  O  O     . SER   C 3 64  ? 57.380  80.424  -24.872 1.00 43.17  ? 357  SER   A O     1 
ATOM   1048  C  CB    . SER   C 3 64  ? 55.375  78.785  -26.874 1.00 37.05  ? 357  SER   A CB    1 
ATOM   1049  O  OG    . SER   C 3 64  ? 55.002  80.154  -26.846 1.00 44.60  ? 357  SER   A OG    1 
ATOM   1050  N  N     . VAL   C 3 65  ? 56.628  78.569  -23.867 1.00 39.50  ? 358  VAL   A N     1 
ATOM   1051  C  CA    . VAL   C 3 65  ? 56.781  79.097  -22.525 1.00 38.50  ? 358  VAL   A CA    1 
ATOM   1052  C  C     . VAL   C 3 65  ? 58.260  79.288  -22.217 1.00 41.08  ? 358  VAL   A C     1 
ATOM   1053  O  O     . VAL   C 3 65  ? 58.634  80.328  -21.702 1.00 41.19  ? 358  VAL   A O     1 
ATOM   1054  C  CB    . VAL   C 3 65  ? 56.115  78.190  -21.475 1.00 38.90  ? 358  VAL   A CB    1 
ATOM   1055  C  CG1   . VAL   C 3 65  ? 56.534  78.562  -20.056 1.00 38.83  ? 358  VAL   A CG1   1 
ATOM   1056  C  CG2   . VAL   C 3 65  ? 54.608  78.225  -21.609 1.00 39.85  ? 358  VAL   A CG2   1 
ATOM   1057  N  N     . LEU   C 3 66  ? 59.081  78.263  -22.483 1.00 42.92  ? 359  LEU   A N     1 
ATOM   1058  C  CA    . LEU   C 3 66  ? 60.521  78.375  -22.316 1.00 41.12  ? 359  LEU   A CA    1 
ATOM   1059  C  C     . LEU   C 3 66  ? 61.054  79.560  -23.118 1.00 39.63  ? 359  LEU   A C     1 
ATOM   1060  O  O     . LEU   C 3 66  ? 61.876  80.325  -22.626 1.00 41.19  ? 359  LEU   A O     1 
ATOM   1061  C  CB    . LEU   C 3 66  ? 61.191  77.077  -22.777 1.00 45.13  ? 359  LEU   A CB    1 
ATOM   1062  C  CG    . LEU   C 3 66  ? 62.706  77.024  -22.577 1.00 45.80  ? 359  LEU   A CG    1 
ATOM   1063  C  CD1   . LEU   C 3 66  ? 63.117  75.793  -21.783 1.00 47.06  ? 359  LEU   A CD1   1 
ATOM   1064  C  CD2   . LEU   C 3 66  ? 63.418  77.087  -23.916 1.00 45.63  ? 359  LEU   A CD2   1 
ATOM   1065  N  N     . ALA   C 3 67  ? 60.574  79.720  -24.350 1.00 38.15  ? 360  ALA   A N     1 
ATOM   1066  C  CA    . ALA   C 3 67  ? 61.023  80.815  -25.193 1.00 40.56  ? 360  ALA   A CA    1 
ATOM   1067  C  C     . ALA   C 3 67  ? 60.722  82.164  -24.529 1.00 46.24  ? 360  ALA   A C     1 
ATOM   1068  O  O     . ALA   C 3 67  ? 61.610  83.007  -24.442 1.00 49.23  ? 360  ALA   A O     1 
ATOM   1069  C  CB    . ALA   C 3 67  ? 60.405  80.704  -26.565 1.00 39.04  ? 360  ALA   A CB    1 
ATOM   1070  N  N     . LEU   C 3 68  ? 59.477  82.356  -24.058 1.00 43.13  ? 361  LEU   A N     1 
ATOM   1071  C  CA    . LEU   C 3 68  ? 59.071  83.565  -23.356 1.00 40.55  ? 361  LEU   A CA    1 
ATOM   1072  C  C     . LEU   C 3 68  ? 59.962  83.851  -22.141 1.00 40.07  ? 361  LEU   A C     1 
ATOM   1073  O  O     . LEU   C 3 68  ? 60.318  85.001  -21.904 1.00 39.75  ? 361  LEU   A O     1 
ATOM   1074  C  CB    . LEU   C 3 68  ? 57.614  83.416  -22.910 1.00 40.80  ? 361  LEU   A CB    1 
ATOM   1075  C  CG    . LEU   C 3 68  ? 56.566  83.587  -24.003 1.00 40.46  ? 361  LEU   A CG    1 
ATOM   1076  C  CD1   . LEU   C 3 68  ? 55.198  83.242  -23.451 1.00 42.08  ? 361  LEU   A CD1   1 
ATOM   1077  C  CD2   . LEU   C 3 68  ? 56.559  85.005  -24.565 1.00 40.51  ? 361  LEU   A CD2   1 
ATOM   1078  N  N     . ARG   C 3 69  ? 60.269  82.825  -21.341 1.00 37.06  ? 362  ARG   A N     1 
ATOM   1079  C  CA    . ARG   C 3 69  ? 61.200  82.936  -20.226 1.00 39.30  ? 362  ARG   A CA    1 
ATOM   1080  C  C     . ARG   C 3 69  ? 62.516  83.574  -20.675 1.00 45.93  ? 362  ARG   A C     1 
ATOM   1081  O  O     . ARG   C 3 69  ? 63.069  84.427  -19.974 1.00 49.05  ? 362  ARG   A O     1 
ATOM   1082  C  CB    . ARG   C 3 69  ? 61.488  81.550  -19.644 1.00 39.05  ? 362  ARG   A CB    1 
ATOM   1083  C  CG    . ARG   C 3 69  ? 62.357  81.558  -18.391 1.00 39.14  ? 362  ARG   A CG    1 
ATOM   1084  C  CD    . ARG   C 3 69  ? 62.808  80.171  -17.982 1.00 36.93  ? 362  ARG   A CD    1 
ATOM   1085  N  NE    . ARG   C 3 69  ? 63.734  79.608  -18.957 1.00 38.50  ? 362  ARG   A NE    1 
ATOM   1086  C  CZ    . ARG   C 3 69  ? 64.108  78.328  -18.983 1.00 41.76  ? 362  ARG   A CZ    1 
ATOM   1087  N  NH1   . ARG   C 3 69  ? 63.519  77.446  -18.195 1.00 40.28  ? 362  ARG   A NH1   1 
ATOM   1088  N  NH2   . ARG   C 3 69  ? 65.060  77.927  -19.807 1.00 42.76  ? 362  ARG   A NH2   1 
ATOM   1089  N  N     . GLU   C 3 70  ? 62.994  83.140  -21.851 1.00 52.20  ? 363  GLU   A N     1 
ATOM   1090  C  CA    . GLU   C 3 70  ? 64.259  83.565  -22.441 1.00 55.83  ? 363  GLU   A CA    1 
ATOM   1091  C  C     . GLU   C 3 70  ? 64.130  84.934  -23.111 1.00 53.08  ? 363  GLU   A C     1 
ATOM   1092  O  O     . GLU   C 3 70  ? 65.118  85.438  -23.624 1.00 57.48  ? 363  GLU   A O     1 
ATOM   1093  C  CB    . GLU   C 3 70  ? 64.731  82.530  -23.476 1.00 56.29  ? 363  GLU   A CB    1 
ATOM   1094  C  CG    . GLU   C 3 70  ? 65.895  81.648  -23.050 1.00 57.62  ? 363  GLU   A CG    1 
ATOM   1095  C  CD    . GLU   C 3 70  ? 65.985  81.201  -21.602 1.00 63.32  ? 363  GLU   A CD    1 
ATOM   1096  O  OE1   . GLU   C 3 70  ? 65.234  80.285  -21.215 1.00 76.67  ? 363  GLU   A OE1   1 
ATOM   1097  O  OE2   . GLU   C 3 70  ? 66.817  81.765  -20.859 1.00 61.34  ? 363  GLU   A OE2   1 
ATOM   1098  N  N     . GLY   C 3 71  ? 62.920  85.507  -23.139 1.00 52.23  ? 364  GLY   A N     1 
ATOM   1099  C  CA    . GLY   C 3 71  ? 62.682  86.820  -23.716 1.00 45.66  ? 364  GLY   A CA    1 
ATOM   1100  C  C     . GLY   C 3 71  ? 62.354  86.766  -25.206 1.00 47.50  ? 364  GLY   A C     1 
ATOM   1101  O  O     . GLY   C 3 71  ? 62.393  87.795  -25.875 1.00 47.17  ? 364  GLY   A O     1 
ATOM   1102  N  N     . LEU   C 3 72  ? 61.992  85.585  -25.722 1.00 48.88  ? 365  LEU   A N     1 
ATOM   1103  C  CA    . LEU   C 3 72  ? 61.627  85.457  -27.126 1.00 53.37  ? 365  LEU   A CA    1 
ATOM   1104  C  C     . LEU   C 3 72  ? 60.131  85.157  -27.267 1.00 55.24  ? 365  LEU   A C     1 
ATOM   1105  O  O     . LEU   C 3 72  ? 59.598  84.277  -26.584 1.00 59.54  ? 365  LEU   A O     1 
ATOM   1106  C  CB    . LEU   C 3 72  ? 62.499  84.365  -27.753 1.00 59.68  ? 365  LEU   A CB    1 
ATOM   1107  C  CG    . LEU   C 3 72  ? 62.236  84.068  -29.229 1.00 70.06  ? 365  LEU   A CG    1 
ATOM   1108  C  CD1   . LEU   C 3 72  ? 62.529  85.281  -30.110 1.00 75.91  ? 365  LEU   A CD1   1 
ATOM   1109  C  CD2   . LEU   C 3 72  ? 63.051  82.865  -29.685 1.00 73.09  ? 365  LEU   A CD2   1 
ATOM   1110  N  N     . GLY   C 3 73  ? 59.476  85.898  -28.175 1.00 52.65  ? 366  GLY   A N     1 
ATOM   1111  C  CA    . GLY   C 3 73  ? 58.060  85.753  -28.473 1.00 50.23  ? 366  GLY   A CA    1 
ATOM   1112  C  C     . GLY   C 3 73  ? 57.831  84.785  -29.633 1.00 51.36  ? 366  GLY   A C     1 
ATOM   1113  O  O     . GLY   C 3 73  ? 57.683  85.206  -30.776 1.00 49.68  ? 366  GLY   A O     1 
ATOM   1114  N  N     . LEU   C 3 74  ? 57.844  83.484  -29.318 1.00 51.64  ? 367  LEU   A N     1 
ATOM   1115  C  CA    . LEU   C 3 74  ? 57.634  82.412  -30.285 1.00 50.75  ? 367  LEU   A CA    1 
ATOM   1116  C  C     . LEU   C 3 74  ? 56.287  81.757  -29.967 1.00 49.36  ? 367  LEU   A C     1 
ATOM   1117  O  O     . LEU   C 3 74  ? 56.178  80.931  -29.049 1.00 43.74  ? 367  LEU   A O     1 
ATOM   1118  C  CB    . LEU   C 3 74  ? 58.796  81.419  -30.152 1.00 50.11  ? 367  LEU   A CB    1 
ATOM   1119  C  CG    . LEU   C 3 74  ? 58.771  80.206  -31.073 1.00 46.61  ? 367  LEU   A CG    1 
ATOM   1120  C  CD1   . LEU   C 3 74  ? 59.229  80.587  -32.461 1.00 49.38  ? 367  LEU   A CD1   1 
ATOM   1121  C  CD2   . LEU   C 3 74  ? 59.646  79.097  -30.516 1.00 48.82  ? 367  LEU   A CD2   1 
ATOM   1122  N  N     . PRO   C 3 75  ? 55.202  82.145  -30.675 1.00 46.00  ? 368  PRO   A N     1 
ATOM   1123  C  CA    . PRO   C 3 75  ? 53.868  81.679  -30.325 1.00 44.05  ? 368  PRO   A CA    1 
ATOM   1124  C  C     . PRO   C 3 75  ? 53.746  80.199  -30.670 1.00 47.07  ? 368  PRO   A C     1 
ATOM   1125  O  O     . PRO   C 3 75  ? 54.380  79.714  -31.606 1.00 45.32  ? 368  PRO   A O     1 
ATOM   1126  C  CB    . PRO   C 3 75  ? 52.940  82.583  -31.159 1.00 43.73  ? 368  PRO   A CB    1 
ATOM   1127  C  CG    . PRO   C 3 75  ? 53.759  82.932  -32.361 1.00 44.22  ? 368  PRO   A CG    1 
ATOM   1128  C  CD    . PRO   C 3 75  ? 55.190  83.025  -31.855 1.00 45.06  ? 368  PRO   A CD    1 
ATOM   1129  N  N     . PRO   C 3 76  ? 52.939  79.428  -29.914 1.00 47.34  ? 369  PRO   A N     1 
ATOM   1130  C  CA    . PRO   C 3 76  ? 52.617  78.064  -30.311 1.00 46.72  ? 369  PRO   A CA    1 
ATOM   1131  C  C     . PRO   C 3 76  ? 51.574  78.093  -31.428 1.00 46.24  ? 369  PRO   A C     1 
ATOM   1132  O  O     . PRO   C 3 76  ? 50.702  78.965  -31.451 1.00 45.96  ? 369  PRO   A O     1 
ATOM   1133  C  CB    . PRO   C 3 76  ? 52.123  77.445  -28.997 1.00 44.74  ? 369  PRO   A CB    1 
ATOM   1134  C  CG    . PRO   C 3 76  ? 51.508  78.597  -28.243 1.00 42.60  ? 369  PRO   A CG    1 
ATOM   1135  C  CD    . PRO   C 3 76  ? 52.269  79.832  -28.673 1.00 44.82  ? 369  PRO   A CD    1 
ATOM   1136  N  N     . GLY   C 3 77  ? 51.715  77.168  -32.386 1.00 43.30  ? 370  GLY   A N     1 
ATOM   1137  C  CA    . GLY   C 3 77  ? 50.688  76.919  -33.391 1.00 41.43  ? 370  GLY   A CA    1 
ATOM   1138  C  C     . GLY   C 3 77  ? 50.166  75.481  -33.303 1.00 39.86  ? 370  GLY   A C     1 
ATOM   1139  O  O     . GLY   C 3 77  ? 49.853  74.988  -32.221 1.00 41.45  ? 370  GLY   A O     1 
ATOM   1140  N  N     . ASP   C 3 78  ? 50.094  74.801  -34.451 1.00 41.03  ? 371  ASP   A N     1 
ATOM   1141  C  CA    . ASP   C 3 78  ? 49.473  73.486  -34.526 1.00 39.92  ? 371  ASP   A CA    1 
ATOM   1142  C  C     . ASP   C 3 78  ? 50.122  72.567  -33.495 1.00 36.40  ? 371  ASP   A C     1 
ATOM   1143  O  O     . ASP   C 3 78  ? 51.328  72.626  -33.281 1.00 36.13  ? 371  ASP   A O     1 
ATOM   1144  C  CB    . ASP   C 3 78  ? 49.552  72.889  -35.941 1.00 38.22  ? 371  ASP   A CB    1 
ATOM   1145  C  CG    . ASP   C 3 78  ? 48.601  73.507  -36.955 1.00 39.30  ? 371  ASP   A CG    1 
ATOM   1146  O  OD1   . ASP   C 3 78  ? 47.397  73.647  -36.639 1.00 41.35  ? 371  ASP   A OD1   1 
ATOM   1147  O  OD2   . ASP   C 3 78  ? 49.059  73.823  -38.064 1.00 40.09  ? 371  ASP   A OD2   1 
ATOM   1148  N  N     . ASP   C 3 79  ? 49.307  71.719  -32.868 1.00 33.58  ? 372  ASP   A N     1 
ATOM   1149  C  CA    . ASP   C 3 79  ? 49.802  70.710  -31.948 1.00 34.09  ? 372  ASP   A CA    1 
ATOM   1150  C  C     . ASP   C 3 79  ? 48.890  69.494  -32.055 1.00 36.57  ? 372  ASP   A C     1 
ATOM   1151  O  O     . ASP   C 3 79  ? 47.717  69.564  -31.694 1.00 37.40  ? 372  ASP   A O     1 
ATOM   1152  C  CB    . ASP   C 3 79  ? 49.893  71.253  -30.521 1.00 32.11  ? 372  ASP   A CB    1 
ATOM   1153  C  CG    . ASP   C 3 79  ? 50.370  70.250  -29.490 1.00 33.05  ? 372  ASP   A CG    1 
ATOM   1154  O  OD1   . ASP   C 3 79  ? 50.494  69.055  -29.837 1.00 35.51  ? 372  ASP   A OD1   1 
ATOM   1155  O  OD2   . ASP   C 3 79  ? 50.590  70.666  -28.331 1.00 32.71  ? 372  ASP   A OD2   1 
ATOM   1156  N  N     . PRO   C 3 80  ? 49.393  68.353  -32.582 1.00 38.10  ? 373  PRO   A N     1 
ATOM   1157  C  CA    . PRO   C 3 80  ? 48.610  67.122  -32.672 1.00 38.50  ? 373  PRO   A CA    1 
ATOM   1158  C  C     . PRO   C 3 80  ? 47.935  66.665  -31.383 1.00 36.28  ? 373  PRO   A C     1 
ATOM   1159  O  O     . PRO   C 3 80  ? 46.897  66.016  -31.443 1.00 38.50  ? 373  PRO   A O     1 
ATOM   1160  C  CB    . PRO   C 3 80  ? 49.662  66.070  -33.079 1.00 39.44  ? 373  PRO   A CB    1 
ATOM   1161  C  CG    . PRO   C 3 80  ? 50.669  66.866  -33.876 1.00 37.88  ? 373  PRO   A CG    1 
ATOM   1162  C  CD    . PRO   C 3 80  ? 50.748  68.190  -33.143 1.00 38.54  ? 373  PRO   A CD    1 
ATOM   1163  N  N     . MET   C 3 81  ? 48.526  66.985  -30.226 1.00 36.14  ? 374  MET   A N     1 
ATOM   1164  C  CA    . MET   C 3 81  ? 47.901  66.671  -28.943 1.00 35.97  ? 374  MET   A CA    1 
ATOM   1165  C  C     . MET   C 3 81  ? 46.500  67.272  -28.844 1.00 33.66  ? 374  MET   A C     1 
ATOM   1166  O  O     . MET   C 3 81  ? 45.605  66.627  -28.302 1.00 35.26  ? 374  MET   A O     1 
ATOM   1167  C  CB    . MET   C 3 81  ? 48.727  67.204  -27.772 1.00 39.53  ? 374  MET   A CB    1 
ATOM   1168  C  CG    . MET   C 3 81  ? 49.982  66.390  -27.493 1.00 41.42  ? 374  MET   A CG    1 
ATOM   1169  S  SD    . MET   C 3 81  ? 49.681  64.627  -27.271 1.00 37.46  ? 374  MET   A SD    1 
ATOM   1170  C  CE    . MET   C 3 81  ? 48.312  64.589  -26.126 1.00 37.64  ? 374  MET   A CE    1 
ATOM   1171  N  N     . LEU   C 3 82  ? 46.316  68.490  -29.384 1.00 31.65  ? 375  LEU   A N     1 
ATOM   1172  C  CA    . LEU   C 3 82  ? 45.029  69.173  -29.339 1.00 33.50  ? 375  LEU   A CA    1 
ATOM   1173  C  C     . LEU   C 3 82  ? 44.019  68.499  -30.277 1.00 32.92  ? 375  LEU   A C     1 
ATOM   1174  O  O     . LEU   C 3 82  ? 42.842  68.361  -29.931 1.00 32.68  ? 375  LEU   A O     1 
ATOM   1175  C  CB    . LEU   C 3 82  ? 45.221  70.656  -29.693 1.00 32.04  ? 375  LEU   A CB    1 
ATOM   1176  C  CG    . LEU   C 3 82  ? 46.084  71.445  -28.717 1.00 33.31  ? 375  LEU   A CG    1 
ATOM   1177  C  CD1   . LEU   C 3 82  ? 46.216  72.888  -29.156 1.00 34.67  ? 375  LEU   A CD1   1 
ATOM   1178  C  CD2   . LEU   C 3 82  ? 45.521  71.360  -27.307 1.00 34.56  ? 375  LEU   A CD2   1 
ATOM   1179  N  N     . LEU   C 3 83  ? 44.481  68.101  -31.474 1.00 32.97  ? 376  LEU   A N     1 
ATOM   1180  C  CA    . LEU   C 3 83  ? 43.658  67.327  -32.398 1.00 28.72  ? 376  LEU   A CA    1 
ATOM   1181  C  C     . LEU   C 3 83  ? 43.210  66.047  -31.715 1.00 26.89  ? 376  LEU   A C     1 
ATOM   1182  O  O     . LEU   C 3 83  ? 42.047  65.687  -31.760 1.00 31.63  ? 376  LEU   A O     1 
ATOM   1183  C  CB    . LEU   C 3 83  ? 44.456  66.986  -33.657 1.00 30.59  ? 376  LEU   A CB    1 
ATOM   1184  C  CG    . LEU   C 3 83  ? 44.843  68.163  -34.548 1.00 32.19  ? 376  LEU   A CG    1 
ATOM   1185  C  CD1   . LEU   C 3 83  ? 45.682  67.671  -35.728 1.00 33.11  ? 376  LEU   A CD1   1 
ATOM   1186  C  CD2   . LEU   C 3 83  ? 43.606  68.907  -35.032 1.00 32.64  ? 376  LEU   A CD2   1 
ATOM   1187  N  N     . ALA   C 3 84  ? 44.151  65.368  -31.068 1.00 28.64  ? 377  ALA   A N     1 
ATOM   1188  C  CA    . ALA   C 3 84  ? 43.886  64.079  -30.450 1.00 29.18  ? 377  ALA   A CA    1 
ATOM   1189  C  C     . ALA   C 3 84  ? 42.926  64.216  -29.271 1.00 29.61  ? 377  ALA   A C     1 
ATOM   1190  O  O     . ALA   C 3 84  ? 42.051  63.374  -29.074 1.00 32.36  ? 377  ALA   A O     1 
ATOM   1191  C  CB    . ALA   C 3 84  ? 45.198  63.470  -30.016 1.00 29.35  ? 377  ALA   A CB    1 
ATOM   1192  N  N     . TYR   C 3 85  ? 43.156  65.239  -28.442 1.00 28.75  ? 378  TYR   A N     1 
ATOM   1193  C  CA    . TYR   C 3 85  ? 42.315  65.503  -27.284 1.00 26.75  ? 378  TYR   A CA    1 
ATOM   1194  C  C     . TYR   C 3 85  ? 40.871  65.748  -27.735 1.00 28.75  ? 378  TYR   A C     1 
ATOM   1195  O  O     . TYR   C 3 85  ? 39.933  65.400  -27.022 1.00 31.30  ? 378  TYR   A O     1 
ATOM   1196  C  CB    . TYR   C 3 85  ? 42.886  66.699  -26.507 1.00 25.75  ? 378  TYR   A CB    1 
ATOM   1197  C  CG    . TYR   C 3 85  ? 42.150  67.075  -25.242 1.00 24.34  ? 378  TYR   A CG    1 
ATOM   1198  C  CD1   . TYR   C 3 85  ? 42.074  66.199  -24.180 1.00 25.26  ? 378  TYR   A CD1   1 
ATOM   1199  C  CD2   . TYR   C 3 85  ? 41.539  68.308  -25.092 1.00 25.91  ? 378  TYR   A CD2   1 
ATOM   1200  C  CE1   . TYR   C 3 85  ? 41.429  66.535  -23.005 1.00 26.20  ? 378  TYR   A CE1   1 
ATOM   1201  C  CE2   . TYR   C 3 85  ? 40.853  68.650  -23.936 1.00 25.20  ? 378  TYR   A CE2   1 
ATOM   1202  C  CZ    . TYR   C 3 85  ? 40.817  67.765  -22.879 1.00 25.74  ? 378  TYR   A CZ    1 
ATOM   1203  O  OH    . TYR   C 3 85  ? 40.165  68.049  -21.706 1.00 28.44  ? 378  TYR   A OH    1 
ATOM   1204  N  N     . LEU   C 3 86  ? 40.683  66.406  -28.891 1.00 30.24  ? 379  LEU   A N     1 
ATOM   1205  C  CA    . LEU   C 3 86  ? 39.345  66.719  -29.389 1.00 30.72  ? 379  LEU   A CA    1 
ATOM   1206  C  C     . LEU   C 3 86  ? 38.680  65.477  -29.977 1.00 31.67  ? 379  LEU   A C     1 
ATOM   1207  O  O     . LEU   C 3 86  ? 37.475  65.290  -29.820 1.00 34.97  ? 379  LEU   A O     1 
ATOM   1208  C  CB    . LEU   C 3 86  ? 39.428  67.843  -30.426 1.00 30.68  ? 379  LEU   A CB    1 
ATOM   1209  C  CG    . LEU   C 3 86  ? 39.578  69.252  -29.850 1.00 30.12  ? 379  LEU   A CG    1 
ATOM   1210  C  CD1   . LEU   C 3 86  ? 39.932  70.241  -30.942 1.00 30.91  ? 379  LEU   A CD1   1 
ATOM   1211  C  CD2   . LEU   C 3 86  ? 38.311  69.704  -29.138 1.00 30.18  ? 379  LEU   A CD2   1 
ATOM   1212  N  N     . LEU   C 3 87  ? 39.473  64.629  -30.643 1.00 33.30  ? 380  LEU   A N     1 
ATOM   1213  C  CA    . LEU   C 3 87  ? 38.996  63.350  -31.153 1.00 33.66  ? 380  LEU   A CA    1 
ATOM   1214  C  C     . LEU   C 3 87  ? 38.493  62.467  -30.009 1.00 31.97  ? 380  LEU   A C     1 
ATOM   1215  O  O     . LEU   C 3 87  ? 37.443  61.839  -30.119 1.00 30.17  ? 380  LEU   A O     1 
ATOM   1216  C  CB    . LEU   C 3 87  ? 40.161  62.707  -31.906 1.00 37.77  ? 380  LEU   A CB    1 
ATOM   1217  C  CG    . LEU   C 3 87  ? 39.841  61.496  -32.778 1.00 43.44  ? 380  LEU   A CG    1 
ATOM   1218  C  CD1   . LEU   C 3 87  ? 38.900  61.837  -33.930 1.00 43.99  ? 380  LEU   A CD1   1 
ATOM   1219  C  CD2   . LEU   C 3 87  ? 41.140  60.926  -33.323 1.00 49.25  ? 380  LEU   A CD2   1 
ATOM   1220  N  N     . ASP   C 3 88  ? 39.235  62.472  -28.889 1.00 32.80  ? 381  ASP   A N     1 
ATOM   1221  C  CA    . ASP   C 3 88  ? 38.914  61.687  -27.707 1.00 33.16  ? 381  ASP   A CA    1 
ATOM   1222  C  C     . ASP   C 3 88  ? 39.711  62.241  -26.525 1.00 32.44  ? 381  ASP   A C     1 
ATOM   1223  O  O     . ASP   C 3 88  ? 40.933  62.120  -26.508 1.00 33.25  ? 381  ASP   A O     1 
ATOM   1224  C  CB    . ASP   C 3 88  ? 39.203  60.214  -28.002 1.00 35.39  ? 381  ASP   A CB    1 
ATOM   1225  C  CG    . ASP   C 3 88  ? 38.769  59.232  -26.934 1.00 36.35  ? 381  ASP   A CG    1 
ATOM   1226  O  OD1   . ASP   C 3 88  ? 38.554  59.652  -25.779 1.00 36.28  ? 381  ASP   A OD1   1 
ATOM   1227  O  OD2   . ASP   C 3 88  ? 38.636  58.047  -27.298 1.00 40.67  ? 381  ASP   A OD2   1 
ATOM   1228  N  N     . PRO   C 3 89  ? 39.066  62.888  -25.521 1.00 30.72  ? 382  PRO   A N     1 
ATOM   1229  C  CA    . PRO   C 3 89  ? 39.781  63.494  -24.393 1.00 30.25  ? 382  PRO   A CA    1 
ATOM   1230  C  C     . PRO   C 3 89  ? 40.446  62.516  -23.414 1.00 34.96  ? 382  PRO   A C     1 
ATOM   1231  O  O     . PRO   C 3 89  ? 41.045  62.953  -22.422 1.00 37.90  ? 382  PRO   A O     1 
ATOM   1232  C  CB    . PRO   C 3 89  ? 38.669  64.305  -23.704 1.00 29.62  ? 382  PRO   A CB    1 
ATOM   1233  C  CG    . PRO   C 3 89  ? 37.421  63.515  -23.975 1.00 28.71  ? 382  PRO   A CG    1 
ATOM   1234  C  CD    . PRO   C 3 89  ? 37.607  63.072  -25.416 1.00 31.18  ? 382  PRO   A CD    1 
ATOM   1235  N  N     . SER   C 3 90  ? 40.346  61.201  -23.700 1.00 33.18  ? 383  SER   A N     1 
ATOM   1236  C  CA    . SER   C 3 90  ? 41.215  60.198  -23.097 1.00 33.72  ? 383  SER   A CA    1 
ATOM   1237  C  C     . SER   C 3 90  ? 42.618  60.245  -23.713 1.00 33.49  ? 383  SER   A C     1 
ATOM   1238  O  O     . SER   C 3 90  ? 43.558  59.681  -23.159 1.00 31.75  ? 383  SER   A O     1 
ATOM   1239  C  CB    . SER   C 3 90  ? 40.610  58.803  -23.171 1.00 32.58  ? 383  SER   A CB    1 
ATOM   1240  O  OG    . SER   C 3 90  ? 40.548  58.319  -24.509 1.00 32.91  ? 383  SER   A OG    1 
ATOM   1241  N  N     . ASN   C 3 91  ? 42.797  60.982  -24.815 1.00 30.98  ? 384  ASN   A N     1 
ATOM   1242  C  CA    . ASN   C 3 91  ? 44.138  61.240  -25.313 1.00 31.32  ? 384  ASN   A CA    1 
ATOM   1243  C  C     . ASN   C 3 91  ? 44.798  62.384  -24.548 1.00 32.11  ? 384  ASN   A C     1 
ATOM   1244  O  O     . ASN   C 3 91  ? 44.577  63.537  -24.895 1.00 33.93  ? 384  ASN   A O     1 
ATOM   1245  C  CB    . ASN   C 3 91  ? 44.113  61.583  -26.800 1.00 30.45  ? 384  ASN   A CB    1 
ATOM   1246  C  CG    . ASN   C 3 91  ? 43.639  60.403  -27.618 1.00 34.54  ? 384  ASN   A CG    1 
ATOM   1247  O  OD1   . ASN   C 3 91  ? 44.067  59.268  -27.367 1.00 29.67  ? 384  ASN   A OD1   1 
ATOM   1248  N  ND2   . ASN   C 3 91  ? 42.732  60.662  -28.551 1.00 29.83  ? 384  ASN   A ND2   1 
ATOM   1249  N  N     . THR   C 3 92  ? 45.656  62.069  -23.564 1.00 32.65  ? 385  THR   A N     1 
ATOM   1250  C  CA    . THR   C 3 92  ? 46.256  63.105  -22.730 1.00 35.64  ? 385  THR   A CA    1 
ATOM   1251  C  C     . THR   C 3 92  ? 47.782  63.222  -22.835 1.00 36.77  ? 385  THR   A C     1 
ATOM   1252  O  O     . THR   C 3 92  ? 48.325  64.241  -22.398 1.00 40.91  ? 385  THR   A O     1 
ATOM   1253  C  CB    . THR   C 3 92  ? 45.873  62.926  -21.259 1.00 33.34  ? 385  THR   A CB    1 
ATOM   1254  O  OG1   . THR   C 3 92  ? 46.339  61.648  -20.842 1.00 32.47  ? 385  THR   A OG1   1 
ATOM   1255  C  CG2   . THR   C 3 92  ? 44.382  63.014  -21.023 1.00 37.16  ? 385  THR   A CG2   1 
ATOM   1256  N  N     . THR   C 3 93  ? 48.486  62.205  -23.353 1.00 37.10  ? 386  THR   A N     1 
ATOM   1257  C  CA    . THR   C 3 93  ? 49.941  62.287  -23.434 1.00 37.05  ? 386  THR   A CA    1 
ATOM   1258  C  C     . THR   C 3 93  ? 50.426  61.969  -24.842 1.00 38.86  ? 386  THR   A C     1 
ATOM   1259  O  O     . THR   C 3 93  ? 49.778  61.225  -25.571 1.00 39.39  ? 386  THR   A O     1 
ATOM   1260  C  CB    . THR   C 3 93  ? 50.640  61.352  -22.440 1.00 35.56  ? 386  THR   A CB    1 
ATOM   1261  O  OG1   . THR   C 3 93  ? 50.334  60.005  -22.800 1.00 39.00  ? 386  THR   A OG1   1 
ATOM   1262  C  CG2   . THR   C 3 93  ? 50.228  61.602  -21.004 1.00 34.19  ? 386  THR   A CG2   1 
ATOM   1263  N  N     . PRO   C 3 94  ? 51.597  62.513  -25.251 1.00 41.44  ? 387  PRO   A N     1 
ATOM   1264  C  CA    . PRO   C 3 94  ? 52.235  62.116  -26.509 1.00 38.07  ? 387  PRO   A CA    1 
ATOM   1265  C  C     . PRO   C 3 94  ? 52.596  60.630  -26.592 1.00 40.25  ? 387  PRO   A C     1 
ATOM   1266  O  O     . PRO   C 3 94  ? 52.528  60.048  -27.670 1.00 40.49  ? 387  PRO   A O     1 
ATOM   1267  C  CB    . PRO   C 3 94  ? 53.530  62.943  -26.557 1.00 39.70  ? 387  PRO   A CB    1 
ATOM   1268  C  CG    . PRO   C 3 94  ? 53.342  64.059  -25.536 1.00 40.51  ? 387  PRO   A CG    1 
ATOM   1269  C  CD    . PRO   C 3 94  ? 52.385  63.510  -24.495 1.00 38.52  ? 387  PRO   A CD    1 
ATOM   1270  N  N     . GLU   C 3 95  ? 53.006  60.019  -25.471 1.00 43.71  ? 388  GLU   A N     1 
ATOM   1271  C  CA    . GLU   C 3 95  ? 53.315  58.593  -25.442 1.00 51.11  ? 388  GLU   A CA    1 
ATOM   1272  C  C     . GLU   C 3 95  ? 52.061  57.836  -25.876 1.00 47.24  ? 388  GLU   A C     1 
ATOM   1273  O  O     . GLU   C 3 95  ? 52.118  56.969  -26.747 1.00 55.64  ? 388  GLU   A O     1 
ATOM   1274  C  CB    . GLU   C 3 95  ? 53.719  58.054  -24.060 1.00 55.00  ? 388  GLU   A CB    1 
ATOM   1275  C  CG    . GLU   C 3 95  ? 54.733  58.895  -23.306 1.00 69.97  ? 388  GLU   A CG    1 
ATOM   1276  C  CD    . GLU   C 3 95  ? 54.189  59.981  -22.381 1.00 74.81  ? 388  GLU   A CD    1 
ATOM   1277  O  OE1   . GLU   C 3 95  ? 54.254  61.191  -22.764 1.00 63.57  ? 388  GLU   A OE1   1 
ATOM   1278  O  OE2   . GLU   C 3 95  ? 53.736  59.631  -21.258 1.00 81.20  ? 388  GLU   A OE2   1 
ATOM   1279  N  N     . GLY   C 3 96  ? 50.935  58.177  -25.236 1.00 41.98  ? 389  GLY   A N     1 
ATOM   1280  C  CA    . GLY   C 3 96  ? 49.672  57.484  -25.444 1.00 41.45  ? 389  GLY   A CA    1 
ATOM   1281  C  C     . GLY   C 3 96  ? 49.129  57.686  -26.856 1.00 38.84  ? 389  GLY   A C     1 
ATOM   1282  O  O     . GLY   C 3 96  ? 48.690  56.728  -27.480 1.00 43.79  ? 389  GLY   A O     1 
ATOM   1283  N  N     . VAL   C 3 97  ? 49.181  58.936  -27.342 1.00 35.93  ? 390  VAL   A N     1 
ATOM   1284  C  CA    . VAL   C 3 97  ? 48.695  59.299  -28.663 1.00 36.02  ? 390  VAL   A CA    1 
ATOM   1285  C  C     . VAL   C 3 97  ? 49.498  58.576  -29.756 1.00 40.06  ? 390  VAL   A C     1 
ATOM   1286  O  O     . VAL   C 3 97  ? 48.918  58.097  -30.729 1.00 36.37  ? 390  VAL   A O     1 
ATOM   1287  C  CB    . VAL   C 3 97  ? 48.729  60.826  -28.837 1.00 33.81  ? 390  VAL   A CB    1 
ATOM   1288  C  CG1   . VAL   C 3 97  ? 48.541  61.256  -30.283 1.00 35.62  ? 390  VAL   A CG1   1 
ATOM   1289  C  CG2   . VAL   C 3 97  ? 47.710  61.506  -27.938 1.00 34.66  ? 390  VAL   A CG2   1 
ATOM   1290  N  N     . ALA   C 3 98  ? 50.829  58.523  -29.612 1.00 41.99  ? 391  ALA   A N     1 
ATOM   1291  C  CA    . ALA   C 3 98  ? 51.691  57.826  -30.559 1.00 45.76  ? 391  ALA   A CA    1 
ATOM   1292  C  C     . ALA   C 3 98  ? 51.358  56.330  -30.589 1.00 47.15  ? 391  ALA   A C     1 
ATOM   1293  O  O     . ALA   C 3 98  ? 51.085  55.769  -31.653 1.00 46.44  ? 391  ALA   A O     1 
ATOM   1294  C  CB    . ALA   C 3 98  ? 53.135  58.064  -30.200 1.00 47.01  ? 391  ALA   A CB    1 
ATOM   1295  N  N     . ARG   C 3 99  ? 51.335  55.708  -29.404 1.00 45.18  ? 392  ARG   A N     1 
ATOM   1296  C  CA    . ARG   C 3 99  ? 50.981  54.301  -29.282 1.00 49.92  ? 392  ARG   A CA    1 
ATOM   1297  C  C     . ARG   C 3 99  ? 49.624  54.023  -29.932 1.00 49.58  ? 392  ARG   A C     1 
ATOM   1298  O  O     . ARG   C 3 99  ? 49.477  53.021  -30.636 1.00 48.53  ? 392  ARG   A O     1 
ATOM   1299  C  CB    . ARG   C 3 99  ? 51.002  53.864  -27.810 1.00 55.20  ? 392  ARG   A CB    1 
ATOM   1300  C  CG    . ARG   C 3 99  ? 51.011  52.349  -27.611 1.00 66.02  ? 392  ARG   A CG    1 
ATOM   1301  C  CD    . ARG   C 3 99  ? 51.876  51.808  -26.477 1.00 76.34  ? 392  ARG   A CD    1 
ATOM   1302  N  NE    . ARG   C 3 99  ? 51.686  52.494  -25.198 1.00 87.70  ? 392  ARG   A NE    1 
ATOM   1303  C  CZ    . ARG   C 3 99  ? 52.619  53.220  -24.570 1.00 90.59  ? 392  ARG   A CZ    1 
ATOM   1304  N  NH1   . ARG   C 3 99  ? 53.894  53.125  -24.919 1.00 75.27  ? 392  ARG   A NH1   1 
ATOM   1305  N  NH2   . ARG   C 3 99  ? 52.271  54.048  -23.596 1.00 86.65  ? 392  ARG   A NH2   1 
ATOM   1306  N  N     . ARG   C 3 100 ? 48.641  54.910  -29.709 1.00 45.42  ? 393  ARG   A N     1 
ATOM   1307  C  CA    . ARG   C 3 100 ? 47.281  54.641  -30.152 1.00 44.68  ? 393  ARG   A CA    1 
ATOM   1308  C  C     . ARG   C 3 100 ? 47.121  54.859  -31.655 1.00 43.88  ? 393  ARG   A C     1 
ATOM   1309  O  O     . ARG   C 3 100 ? 46.331  54.146  -32.284 1.00 46.78  ? 393  ARG   A O     1 
ATOM   1310  C  CB    . ARG   C 3 100 ? 46.266  55.486  -29.379 1.00 47.05  ? 393  ARG   A CB    1 
ATOM   1311  C  CG    . ARG   C 3 100 ? 44.848  55.348  -29.909 1.00 45.99  ? 393  ARG   A CG    1 
ATOM   1312  C  CD    . ARG   C 3 100 ? 43.743  55.225  -28.877 1.00 47.45  ? 393  ARG   A CD    1 
ATOM   1313  N  NE    . ARG   C 3 100 ? 43.000  56.432  -28.598 1.00 46.58  ? 393  ARG   A NE    1 
ATOM   1314  C  CZ    . ARG   C 3 100 ? 41.806  56.459  -28.012 1.00 46.99  ? 393  ARG   A CZ    1 
ATOM   1315  N  NH1   . ARG   C 3 100 ? 40.788  55.794  -28.524 1.00 41.93  ? 393  ARG   A NH1   1 
ATOM   1316  N  NH2   . ARG   C 3 100 ? 41.626  57.207  -26.937 1.00 47.11  ? 393  ARG   A NH2   1 
ATOM   1317  N  N     . TYR   C 3 101 ? 47.836  55.843  -32.224 1.00 39.16  ? 394  TYR   A N     1 
ATOM   1318  C  CA    . TYR   C 3 101 ? 47.536  56.304  -33.571 1.00 40.74  ? 394  TYR   A CA    1 
ATOM   1319  C  C     . TYR   C 3 101 ? 48.706  56.125  -34.545 1.00 48.07  ? 394  TYR   A C     1 
ATOM   1320  O  O     . TYR   C 3 101 ? 48.481  56.197  -35.753 1.00 46.71  ? 394  TYR   A O     1 
ATOM   1321  C  CB    . TYR   C 3 101 ? 47.112  57.775  -33.547 1.00 40.33  ? 394  TYR   A CB    1 
ATOM   1322  C  CG    . TYR   C 3 101 ? 45.834  58.021  -32.793 1.00 42.51  ? 394  TYR   A CG    1 
ATOM   1323  C  CD1   . TYR   C 3 101 ? 44.628  57.522  -33.255 1.00 37.95  ? 394  TYR   A CD1   1 
ATOM   1324  C  CD2   . TYR   C 3 101 ? 45.839  58.687  -31.577 1.00 42.00  ? 394  TYR   A CD2   1 
ATOM   1325  C  CE1   . TYR   C 3 101 ? 43.457  57.688  -32.539 1.00 39.81  ? 394  TYR   A CE1   1 
ATOM   1326  C  CE2   . TYR   C 3 101 ? 44.674  58.868  -30.852 1.00 41.36  ? 394  TYR   A CE2   1 
ATOM   1327  C  CZ    . TYR   C 3 101 ? 43.474  58.387  -31.343 1.00 40.77  ? 394  TYR   A CZ    1 
ATOM   1328  O  OH    . TYR   C 3 101 ? 42.315  58.574  -30.618 1.00 34.60  ? 394  TYR   A OH    1 
ATOM   1329  N  N     . GLY   C 3 102 ? 49.948  55.962  -34.055 1.00 51.26  ? 395  GLY   A N     1 
ATOM   1330  C  CA    . GLY   C 3 102 ? 51.061  55.685  -34.955 1.00 52.69  ? 395  GLY   A CA    1 
ATOM   1331  C  C     . GLY   C 3 102 ? 52.354  56.412  -34.594 1.00 54.12  ? 395  GLY   A C     1 
ATOM   1332  O  O     . GLY   C 3 102 ? 52.365  57.632  -34.410 1.00 57.66  ? 395  GLY   A O     1 
ATOM   1333  N  N     . GLY   C 3 103 ? 53.449  55.641  -34.569 1.00 49.75  ? 396  GLY   A N     1 
ATOM   1334  C  CA    . GLY   C 3 103 ? 54.773  56.141  -34.250 1.00 45.76  ? 396  GLY   A CA    1 
ATOM   1335  C  C     . GLY   C 3 103 ? 55.118  55.857  -32.794 1.00 49.07  ? 396  GLY   A C     1 
ATOM   1336  O  O     . GLY   C 3 103 ? 54.397  55.120  -32.118 1.00 43.91  ? 396  GLY   A O     1 
ATOM   1337  N  N     . GLU   C 3 104 ? 56.217  56.463  -32.323 1.00 53.07  ? 397  GLU   A N     1 
ATOM   1338  C  CA    . GLU   C 3 104 ? 56.689  56.264  -30.958 1.00 55.99  ? 397  GLU   A CA    1 
ATOM   1339  C  C     . GLU   C 3 104 ? 57.245  57.579  -30.393 1.00 51.74  ? 397  GLU   A C     1 
ATOM   1340  O  O     . GLU   C 3 104 ? 57.984  58.303  -31.068 1.00 44.72  ? 397  GLU   A O     1 
ATOM   1341  C  CB    . GLU   C 3 104 ? 57.745  55.155  -30.947 1.00 56.08  ? 397  GLU   A CB    1 
ATOM   1342  C  CG    . GLU   C 3 104 ? 58.009  54.577  -29.566 1.00 59.78  ? 397  GLU   A CG    1 
ATOM   1343  C  CD    . GLU   C 3 104 ? 59.273  53.734  -29.473 1.00 63.02  ? 397  GLU   A CD    1 
ATOM   1344  O  OE1   . GLU   C 3 104 ? 59.963  53.578  -30.510 1.00 60.27  ? 397  GLU   A OE1   1 
ATOM   1345  O  OE2   . GLU   C 3 104 ? 59.576  53.247  -28.360 1.00 61.41  ? 397  GLU   A OE2   1 
ATOM   1346  N  N     . TRP   C 3 105 ? 56.861  57.890  -29.148 1.00 48.09  ? 398  TRP   A N     1 
ATOM   1347  C  CA    . TRP   C 3 105 ? 57.406  59.036  -28.427 1.00 48.02  ? 398  TRP   A CA    1 
ATOM   1348  C  C     . TRP   C 3 105 ? 58.759  58.644  -27.847 1.00 48.27  ? 398  TRP   A C     1 
ATOM   1349  O  O     . TRP   C 3 105 ? 58.801  57.893  -26.871 1.00 45.88  ? 398  TRP   A O     1 
ATOM   1350  C  CB    . TRP   C 3 105 ? 56.454  59.475  -27.308 1.00 41.07  ? 398  TRP   A CB    1 
ATOM   1351  C  CG    . TRP   C 3 105 ? 56.895  60.633  -26.458 1.00 39.42  ? 398  TRP   A CG    1 
ATOM   1352  C  CD1   . TRP   C 3 105 ? 57.207  60.600  -25.123 1.00 36.87  ? 398  TRP   A CD1   1 
ATOM   1353  C  CD2   . TRP   C 3 105 ? 56.973  62.015  -26.855 1.00 35.21  ? 398  TRP   A CD2   1 
ATOM   1354  N  NE1   . TRP   C 3 105 ? 57.502  61.858  -24.675 1.00 37.41  ? 398  TRP   A NE1   1 
ATOM   1355  C  CE2   . TRP   C 3 105 ? 57.354  62.750  -25.713 1.00 38.76  ? 398  TRP   A CE2   1 
ATOM   1356  C  CE3   . TRP   C 3 105 ? 56.739  62.699  -28.053 1.00 37.19  ? 398  TRP   A CE3   1 
ATOM   1357  C  CZ2   . TRP   C 3 105 ? 57.515  64.138  -25.741 1.00 37.49  ? 398  TRP   A CZ2   1 
ATOM   1358  C  CZ3   . TRP   C 3 105 ? 56.917  64.063  -28.092 1.00 39.50  ? 398  TRP   A CZ3   1 
ATOM   1359  C  CH2   . TRP   C 3 105 ? 57.305  64.773  -26.947 1.00 40.77  ? 398  TRP   A CH2   1 
ATOM   1360  N  N     . THR   C 3 106 ? 59.840  59.158  -28.449 1.00 49.68  ? 399  THR   A N     1 
ATOM   1361  C  CA    . THR   C 3 106 ? 61.177  58.844  -27.969 1.00 53.91  ? 399  THR   A CA    1 
ATOM   1362  C  C     . THR   C 3 106 ? 61.702  60.031  -27.156 1.00 57.56  ? 399  THR   A C     1 
ATOM   1363  O  O     . THR   C 3 106 ? 60.938  60.938  -26.814 1.00 54.39  ? 399  THR   A O     1 
ATOM   1364  C  CB    . THR   C 3 106 ? 62.055  58.381  -29.140 1.00 48.88  ? 399  THR   A CB    1 
ATOM   1365  O  OG1   . THR   C 3 106 ? 62.191  59.455  -30.069 1.00 48.68  ? 399  THR   A OG1   1 
ATOM   1366  C  CG2   . THR   C 3 106 ? 61.479  57.175  -29.851 1.00 49.23  ? 399  THR   A CG2   1 
ATOM   1367  N  N     . GLU   C 3 107 ? 62.999  59.982  -26.806 1.00 54.88  ? 400  GLU   A N     1 
ATOM   1368  C  CA    . GLU   C 3 107 ? 63.648  61.028  -26.030 1.00 55.28  ? 400  GLU   A CA    1 
ATOM   1369  C  C     . GLU   C 3 107 ? 64.679  61.739  -26.902 1.00 55.39  ? 400  GLU   A C     1 
ATOM   1370  O  O     . GLU   C 3 107 ? 65.701  62.200  -26.394 1.00 61.83  ? 400  GLU   A O     1 
ATOM   1371  C  CB    . GLU   C 3 107 ? 64.322  60.466  -24.771 1.00 60.94  ? 400  GLU   A CB    1 
ATOM   1372  C  CG    . GLU   C 3 107 ? 63.393  59.679  -23.849 1.00 66.12  ? 400  GLU   A CG    1 
ATOM   1373  C  CD    . GLU   C 3 107 ? 62.277  60.483  -23.203 1.00 74.36  ? 400  GLU   A CD    1 
ATOM   1374  O  OE1   . GLU   C 3 107 ? 62.602  61.470  -22.509 1.00 77.50  ? 400  GLU   A OE1   1 
ATOM   1375  O  OE2   . GLU   C 3 107 ? 61.085  60.129  -23.402 1.00 79.82  ? 400  GLU   A OE2   1 
ATOM   1376  N  N     . GLU   C 3 108 ? 64.387  61.858  -28.204 1.00 49.66  ? 401  GLU   A N     1 
ATOM   1377  C  CA    . GLU   C 3 108 ? 65.319  62.456  -29.139 1.00 48.88  ? 401  GLU   A CA    1 
ATOM   1378  C  C     . GLU   C 3 108 ? 64.555  63.489  -29.962 1.00 48.47  ? 401  GLU   A C     1 
ATOM   1379  O  O     . GLU   C 3 108 ? 63.562  63.164  -30.608 1.00 51.39  ? 401  GLU   A O     1 
ATOM   1380  C  CB    . GLU   C 3 108 ? 65.980  61.356  -29.987 1.00 53.69  ? 401  GLU   A CB    1 
ATOM   1381  C  CG    . GLU   C 3 108 ? 67.250  61.786  -30.729 1.00 53.65  ? 401  GLU   A CG    1 
ATOM   1382  C  CD    . GLU   C 3 108 ? 67.028  62.585  -32.008 1.00 61.14  ? 401  GLU   A CD    1 
ATOM   1383  O  OE1   . GLU   C 3 108 ? 67.610  63.698  -32.137 1.00 60.14  ? 401  GLU   A OE1   1 
ATOM   1384  O  OE2   . GLU   C 3 108 ? 66.270  62.102  -32.892 1.00 64.95  ? 401  GLU   A OE2   1 
ATOM   1385  N  N     . ALA   C 3 109 ? 65.044  64.735  -29.933 1.00 47.71  ? 402  ALA   A N     1 
ATOM   1386  C  CA    . ALA   C 3 109 ? 64.376  65.863  -30.556 1.00 49.64  ? 402  ALA   A CA    1 
ATOM   1387  C  C     . ALA   C 3 109 ? 63.959  65.557  -31.995 1.00 47.61  ? 402  ALA   A C     1 
ATOM   1388  O  O     . ALA   C 3 109 ? 62.827  65.822  -32.371 1.00 47.81  ? 402  ALA   A O     1 
ATOM   1389  C  CB    . ALA   C 3 109 ? 65.265  67.085  -30.492 1.00 52.92  ? 402  ALA   A CB    1 
ATOM   1390  N  N     . GLY   C 3 110 ? 64.877  65.034  -32.809 1.00 50.55  ? 403  GLY   A N     1 
ATOM   1391  C  CA    . GLY   C 3 110 ? 64.624  64.827  -34.229 1.00 47.82  ? 403  GLY   A CA    1 
ATOM   1392  C  C     . GLY   C 3 110 ? 63.498  63.832  -34.506 1.00 44.75  ? 403  GLY   A C     1 
ATOM   1393  O  O     . GLY   C 3 110 ? 62.699  64.023  -35.416 1.00 43.81  ? 403  GLY   A O     1 
ATOM   1394  N  N     . GLU   C 3 111 ? 63.459  62.759  -33.724 1.00 45.44  ? 404  GLU   A N     1 
ATOM   1395  C  CA    . GLU   C 3 111 ? 62.393  61.779  -33.809 1.00 49.79  ? 404  GLU   A CA    1 
ATOM   1396  C  C     . GLU   C 3 111 ? 61.063  62.439  -33.434 1.00 53.76  ? 404  GLU   A C     1 
ATOM   1397  O  O     . GLU   C 3 111 ? 60.068  62.251  -34.129 1.00 51.05  ? 404  GLU   A O     1 
ATOM   1398  C  CB    . GLU   C 3 111 ? 62.754  60.588  -32.913 1.00 50.62  ? 404  GLU   A CB    1 
ATOM   1399  C  CG    . GLU   C 3 111 ? 63.886  59.747  -33.496 1.00 54.32  ? 404  GLU   A CG    1 
ATOM   1400  C  CD    . GLU   C 3 111 ? 64.415  58.596  -32.651 1.00 58.03  ? 404  GLU   A CD    1 
ATOM   1401  O  OE1   . GLU   C 3 111 ? 64.139  58.547  -31.442 1.00 53.84  ? 404  GLU   A OE1   1 
ATOM   1402  O  OE2   . GLU   C 3 111 ? 65.109  57.740  -33.221 1.00 73.48  ? 404  GLU   A OE2   1 
ATOM   1403  N  N     . ARG   C 3 112 ? 61.074  63.223  -32.340 1.00 50.24  ? 405  ARG   A N     1 
ATOM   1404  C  CA    . ARG   C 3 112 ? 59.897  63.925  -31.846 1.00 43.36  ? 405  ARG   A CA    1 
ATOM   1405  C  C     . ARG   C 3 112 ? 59.382  64.889  -32.903 1.00 41.64  ? 405  ARG   A C     1 
ATOM   1406  O  O     . ARG   C 3 112 ? 58.177  65.093  -33.011 1.00 42.78  ? 405  ARG   A O     1 
ATOM   1407  C  CB    . ARG   C 3 112 ? 60.189  64.689  -30.549 1.00 38.92  ? 405  ARG   A CB    1 
ATOM   1408  C  CG    . ARG   C 3 112 ? 60.351  63.790  -29.330 1.00 38.77  ? 405  ARG   A CG    1 
ATOM   1409  C  CD    . ARG   C 3 112 ? 60.649  64.587  -28.077 1.00 39.24  ? 405  ARG   A CD    1 
ATOM   1410  N  NE    . ARG   C 3 112 ? 60.778  63.749  -26.897 1.00 36.84  ? 405  ARG   A NE    1 
ATOM   1411  C  CZ    . ARG   C 3 112 ? 60.720  64.200  -25.646 1.00 39.26  ? 405  ARG   A CZ    1 
ATOM   1412  N  NH1   . ARG   C 3 112 ? 60.815  65.495  -25.370 1.00 35.80  ? 405  ARG   A NH1   1 
ATOM   1413  N  NH2   . ARG   C 3 112 ? 60.570  63.333  -24.664 1.00 43.59  ? 405  ARG   A NH2   1 
ATOM   1414  N  N     . ALA   C 3 113 ? 60.286  65.481  -33.685 1.00 41.93  ? 406  ALA   A N     1 
ATOM   1415  C  CA    . ALA   C 3 113 ? 59.876  66.455  -34.686 1.00 40.84  ? 406  ALA   A CA    1 
ATOM   1416  C  C     . ALA   C 3 113 ? 59.214  65.766  -35.875 1.00 41.60  ? 406  ALA   A C     1 
ATOM   1417  O  O     . ALA   C 3 113 ? 58.310  66.335  -36.483 1.00 43.06  ? 406  ALA   A O     1 
ATOM   1418  C  CB    . ALA   C 3 113 ? 61.056  67.277  -35.121 1.00 42.37  ? 406  ALA   A CB    1 
ATOM   1419  N  N     . ALA   C 3 114 ? 59.701  64.565  -36.225 1.00 45.32  ? 407  ALA   A N     1 
ATOM   1420  C  CA    . ALA   C 3 114 ? 59.157  63.798  -37.341 1.00 45.69  ? 407  ALA   A CA    1 
ATOM   1421  C  C     . ALA   C 3 114 ? 57.802  63.219  -36.945 1.00 42.55  ? 407  ALA   A C     1 
ATOM   1422  O  O     . ALA   C 3 114 ? 56.871  63.246  -37.735 1.00 48.63  ? 407  ALA   A O     1 
ATOM   1423  C  CB    . ALA   C 3 114 ? 60.117  62.703  -37.761 1.00 43.82  ? 407  ALA   A CB    1 
ATOM   1424  N  N     . LEU   C 3 115 ? 57.717  62.689  -35.719 1.00 43.04  ? 408  LEU   A N     1 
ATOM   1425  C  CA    . LEU   C 3 115 ? 56.465  62.217  -35.138 1.00 42.87  ? 408  LEU   A CA    1 
ATOM   1426  C  C     . LEU   C 3 115 ? 55.405  63.328  -35.160 1.00 43.80  ? 408  LEU   A C     1 
ATOM   1427  O  O     . LEU   C 3 115 ? 54.268  63.098  -35.564 1.00 45.49  ? 408  LEU   A O     1 
ATOM   1428  C  CB    . LEU   C 3 115 ? 56.762  61.726  -33.720 1.00 39.38  ? 408  LEU   A CB    1 
ATOM   1429  C  CG    . LEU   C 3 115 ? 55.572  61.171  -32.934 1.00 42.44  ? 408  LEU   A CG    1 
ATOM   1430  C  CD1   . LEU   C 3 115 ? 55.004  59.915  -33.589 1.00 37.81  ? 408  LEU   A CD1   1 
ATOM   1431  C  CD2   . LEU   C 3 115 ? 55.983  60.882  -31.489 1.00 39.08  ? 408  LEU   A CD2   1 
ATOM   1432  N  N     . SER   C 3 116 ? 55.796  64.548  -34.782 1.00 38.83  ? 409  SER   A N     1 
ATOM   1433  C  CA    . SER   C 3 116 ? 54.888  65.675  -34.775 1.00 38.25  ? 409  SER   A CA    1 
ATOM   1434  C  C     . SER   C 3 116 ? 54.260  65.832  -36.150 1.00 40.34  ? 409  SER   A C     1 
ATOM   1435  O  O     . SER   C 3 116 ? 53.045  66.000  -36.260 1.00 43.28  ? 409  SER   A O     1 
ATOM   1436  C  CB    . SER   C 3 116 ? 55.589  66.944  -34.337 1.00 38.51  ? 409  SER   A CB    1 
ATOM   1437  O  OG    . SER   C 3 116 ? 56.001  66.854  -32.980 1.00 37.29  ? 409  SER   A OG    1 
ATOM   1438  N  N     . GLU   C 3 117 ? 55.099  65.773  -37.195 1.00 44.90  ? 410  GLU   A N     1 
ATOM   1439  C  CA    . GLU   C 3 117 ? 54.633  65.952  -38.563 1.00 44.40  ? 410  GLU   A CA    1 
ATOM   1440  C  C     . GLU   C 3 117 ? 53.642  64.859  -38.976 1.00 44.06  ? 410  GLU   A C     1 
ATOM   1441  O  O     . GLU   C 3 117 ? 52.602  65.156  -39.568 1.00 44.25  ? 410  GLU   A O     1 
ATOM   1442  C  CB    . GLU   C 3 117 ? 55.813  65.966  -39.524 1.00 44.52  ? 410  GLU   A CB    1 
ATOM   1443  C  CG    . GLU   C 3 117 ? 55.401  66.168  -40.975 1.00 49.33  ? 410  GLU   A CG    1 
ATOM   1444  C  CD    . GLU   C 3 117 ? 56.588  66.288  -41.918 1.00 51.60  ? 410  GLU   A CD    1 
ATOM   1445  O  OE1   . GLU   C 3 117 ? 57.566  65.521  -41.733 1.00 48.70  ? 410  GLU   A OE1   1 
ATOM   1446  O  OE2   . GLU   C 3 117 ? 56.533  67.151  -42.816 1.00 47.40  ? 410  GLU   A OE2   1 
ATOM   1447  N  N     . ARG   C 3 118 ? 53.984  63.602  -38.672 1.00 46.41  ? 411  ARG   A N     1 
ATOM   1448  C  CA    . ARG   C 3 118 ? 53.191  62.454  -39.085 1.00 52.89  ? 411  ARG   A CA    1 
ATOM   1449  C  C     . ARG   C 3 118 ? 51.862  62.433  -38.324 1.00 49.60  ? 411  ARG   A C     1 
ATOM   1450  O  O     . ARG   C 3 118 ? 50.801  62.313  -38.939 1.00 46.56  ? 411  ARG   A O     1 
ATOM   1451  C  CB    . ARG   C 3 118 ? 53.970  61.146  -38.869 1.00 60.76  ? 411  ARG   A CB    1 
ATOM   1452  C  CG    . ARG   C 3 118 ? 55.185  60.961  -39.775 1.00 72.97  ? 411  ARG   A CG    1 
ATOM   1453  C  CD    . ARG   C 3 118 ? 55.550  59.496  -40.016 1.00 82.31  ? 411  ARG   A CD    1 
ATOM   1454  N  NE    . ARG   C 3 118 ? 54.646  58.895  -41.001 1.00 88.83  ? 411  ARG   A NE    1 
ATOM   1455  C  CZ    . ARG   C 3 118 ? 54.997  58.046  -41.966 1.00 83.39  ? 411  ARG   A CZ    1 
ATOM   1456  N  NH1   . ARG   C 3 118 ? 54.369  58.079  -43.129 1.00 73.79  ? 411  ARG   A NH1   1 
ATOM   1457  N  NH2   . ARG   C 3 118 ? 55.972  57.174  -41.768 1.00 81.97  ? 411  ARG   A NH2   1 
ATOM   1458  N  N     . LEU   C 3 119 ? 51.927  62.536  -36.987 1.00 43.54  ? 412  LEU   A N     1 
ATOM   1459  C  CA    . LEU   C 3 119 ? 50.728  62.572  -36.156 1.00 42.78  ? 412  LEU   A CA    1 
ATOM   1460  C  C     . LEU   C 3 119 ? 49.839  63.752  -36.543 1.00 39.38  ? 412  LEU   A C     1 
ATOM   1461  O  O     . LEU   C 3 119 ? 48.623  63.646  -36.455 1.00 38.90  ? 412  LEU   A O     1 
ATOM   1462  C  CB    . LEU   C 3 119 ? 51.105  62.646  -34.676 1.00 41.85  ? 412  LEU   A CB    1 
ATOM   1463  C  CG    . LEU   C 3 119 ? 51.450  61.321  -33.999 1.00 41.41  ? 412  LEU   A CG    1 
ATOM   1464  C  CD1   . LEU   C 3 119 ? 51.756  61.544  -32.527 1.00 40.97  ? 412  LEU   A CD1   1 
ATOM   1465  C  CD2   . LEU   C 3 119 ? 50.313  60.307  -34.148 1.00 44.68  ? 412  LEU   A CD2   1 
ATOM   1466  N  N     . PHE   C 3 120 ? 50.411  64.851  -37.031 1.00 38.59  ? 413  PHE   A N     1 
ATOM   1467  C  CA    . PHE   C 3 120 ? 49.551  65.971  -37.392 1.00 41.42  ? 413  PHE   A CA    1 
ATOM   1468  C  C     . PHE   C 3 120 ? 48.619  65.600  -38.535 1.00 42.06  ? 413  PHE   A C     1 
ATOM   1469  O  O     . PHE   C 3 120 ? 47.421  65.847  -38.426 1.00 45.63  ? 413  PHE   A O     1 
ATOM   1470  C  CB    . PHE   C 3 120 ? 50.295  67.236  -37.828 1.00 43.11  ? 413  PHE   A CB    1 
ATOM   1471  C  CG    . PHE   C 3 120 ? 49.360  68.400  -38.071 1.00 42.26  ? 413  PHE   A CG    1 
ATOM   1472  C  CD1   . PHE   C 3 120 ? 48.685  69.001  -37.015 1.00 43.25  ? 413  PHE   A CD1   1 
ATOM   1473  C  CD2   . PHE   C 3 120 ? 49.101  68.860  -39.352 1.00 47.42  ? 413  PHE   A CD2   1 
ATOM   1474  C  CE1   . PHE   C 3 120 ? 47.816  70.064  -37.233 1.00 45.48  ? 413  PHE   A CE1   1 
ATOM   1475  C  CE2   . PHE   C 3 120 ? 48.211  69.908  -39.576 1.00 46.75  ? 413  PHE   A CE2   1 
ATOM   1476  C  CZ    . PHE   C 3 120 ? 47.572  70.510  -38.516 1.00 45.70  ? 413  PHE   A CZ    1 
ATOM   1477  N  N     . ALA   C 3 121 ? 49.180  65.086  -39.648 1.00 43.29  ? 414  ALA   A N     1 
ATOM   1478  C  CA    . ALA   C 3 121 ? 48.386  64.727  -40.828 1.00 40.79  ? 414  ALA   A CA    1 
ATOM   1479  C  C     . ALA   C 3 121 ? 47.473  63.535  -40.541 1.00 37.50  ? 414  ALA   A C     1 
ATOM   1480  O  O     . ALA   C 3 121 ? 46.365  63.472  -41.050 1.00 42.18  ? 414  ALA   A O     1 
ATOM   1481  C  CB    . ALA   C 3 121 ? 49.282  64.408  -41.998 1.00 39.37  ? 414  ALA   A CB    1 
ATOM   1482  N  N     . ASN   C 3 122 ? 47.977  62.577  -39.755 1.00 35.86  ? 415  ASN   A N     1 
ATOM   1483  C  CA    . ASN   C 3 122 ? 47.253  61.380  -39.364 1.00 37.25  ? 415  ASN   A CA    1 
ATOM   1484  C  C     . ASN   C 3 122 ? 45.963  61.745  -38.612 1.00 41.70  ? 415  ASN   A C     1 
ATOM   1485  O  O     . ASN   C 3 122 ? 44.874  61.312  -39.004 1.00 40.61  ? 415  ASN   A O     1 
ATOM   1486  C  CB    . ASN   C 3 122 ? 48.213  60.465  -38.601 1.00 38.70  ? 415  ASN   A CB    1 
ATOM   1487  C  CG    . ASN   C 3 122 ? 47.564  59.265  -37.949 1.00 43.99  ? 415  ASN   A CG    1 
ATOM   1488  O  OD1   . ASN   C 3 122 ? 46.361  59.262  -37.688 1.00 50.82  ? 415  ASN   A OD1   1 
ATOM   1489  N  ND2   . ASN   C 3 122 ? 48.366  58.259  -37.633 1.00 44.47  ? 415  ASN   A ND2   1 
ATOM   1490  N  N     . LEU   C 3 123 ? 46.084  62.585  -37.565 1.00 40.87  ? 416  LEU   A N     1 
ATOM   1491  C  CA    . LEU   C 3 123 ? 44.960  62.991  -36.725 1.00 39.39  ? 416  LEU   A CA    1 
ATOM   1492  C  C     . LEU   C 3 123 ? 44.042  63.965  -37.452 1.00 36.94  ? 416  LEU   A C     1 
ATOM   1493  O  O     . LEU   C 3 123 ? 42.836  63.901  -37.280 1.00 39.89  ? 416  LEU   A O     1 
ATOM   1494  C  CB    . LEU   C 3 123 ? 45.497  63.603  -35.428 1.00 37.69  ? 416  LEU   A CB    1 
ATOM   1495  C  CG    . LEU   C 3 123 ? 46.127  62.574  -34.496 1.00 39.27  ? 416  LEU   A CG    1 
ATOM   1496  C  CD1   . LEU   C 3 123 ? 46.943  63.248  -33.404 1.00 45.79  ? 416  LEU   A CD1   1 
ATOM   1497  C  CD2   . LEU   C 3 123 ? 45.058  61.680  -33.896 1.00 39.52  ? 416  LEU   A CD2   1 
ATOM   1498  N  N     . TRP   C 3 124 ? 44.610  64.867  -38.243 1.00 38.75  ? 417  TRP   A N     1 
ATOM   1499  C  CA    . TRP   C 3 124 ? 43.819  65.706  -39.127 1.00 40.50  ? 417  TRP   A CA    1 
ATOM   1500  C  C     . TRP   C 3 124 ? 42.913  64.832  -39.992 1.00 40.54  ? 417  TRP   A C     1 
ATOM   1501  O  O     . TRP   C 3 124 ? 41.697  65.030  -40.029 1.00 45.14  ? 417  TRP   A O     1 
ATOM   1502  C  CB    . TRP   C 3 124 ? 44.726  66.604  -39.991 1.00 42.50  ? 417  TRP   A CB    1 
ATOM   1503  C  CG    . TRP   C 3 124 ? 43.962  67.676  -40.706 1.00 45.91  ? 417  TRP   A CG    1 
ATOM   1504  C  CD1   . TRP   C 3 124 ? 43.495  67.629  -41.990 1.00 46.90  ? 417  TRP   A CD1   1 
ATOM   1505  C  CD2   . TRP   C 3 124 ? 43.523  68.934  -40.162 1.00 45.29  ? 417  TRP   A CD2   1 
ATOM   1506  N  NE1   . TRP   C 3 124 ? 42.807  68.773  -42.287 1.00 50.67  ? 417  TRP   A NE1   1 
ATOM   1507  C  CE2   . TRP   C 3 124 ? 42.814  69.597  -41.191 1.00 50.40  ? 417  TRP   A CE2   1 
ATOM   1508  C  CE3   . TRP   C 3 124 ? 43.667  69.574  -38.923 1.00 47.04  ? 417  TRP   A CE3   1 
ATOM   1509  C  CZ2   . TRP   C 3 124 ? 42.247  70.859  -41.007 1.00 48.18  ? 417  TRP   A CZ2   1 
ATOM   1510  C  CZ3   . TRP   C 3 124 ? 43.121  70.832  -38.748 1.00 47.11  ? 417  TRP   A CZ3   1 
ATOM   1511  C  CH2   . TRP   C 3 124 ? 42.411  71.460  -39.776 1.00 47.39  ? 417  TRP   A CH2   1 
ATOM   1512  N  N     . GLY   C 3 125 ? 43.519  63.843  -40.667 1.00 41.08  ? 418  GLY   A N     1 
ATOM   1513  C  CA    . GLY   C 3 125 ? 42.783  62.881  -41.473 1.00 37.38  ? 418  GLY   A CA    1 
ATOM   1514  C  C     . GLY   C 3 125 ? 41.657  62.199  -40.692 1.00 35.64  ? 418  GLY   A C     1 
ATOM   1515  O  O     . GLY   C 3 125 ? 40.551  62.050  -41.193 1.00 38.46  ? 418  GLY   A O     1 
ATOM   1516  N  N     . ARG   C 3 126 ? 41.934  61.777  -39.454 1.00 38.65  ? 419  ARG   A N     1 
ATOM   1517  C  CA    . ARG   C 3 126 ? 40.936  61.080  -38.646 1.00 37.01  ? 419  ARG   A CA    1 
ATOM   1518  C  C     . ARG   C 3 126 ? 39.804  62.014  -38.224 1.00 36.61  ? 419  ARG   A C     1 
ATOM   1519  O  O     . ARG   C 3 126 ? 38.737  61.563  -37.824 1.00 34.76  ? 419  ARG   A O     1 
ATOM   1520  C  CB    . ARG   C 3 126 ? 41.607  60.476  -37.417 1.00 35.80  ? 419  ARG   A CB    1 
ATOM   1521  C  CG    . ARG   C 3 126 ? 42.515  59.322  -37.778 1.00 37.41  ? 419  ARG   A CG    1 
ATOM   1522  C  CD    . ARG   C 3 126 ? 43.262  58.801  -36.581 1.00 42.65  ? 419  ARG   A CD    1 
ATOM   1523  N  NE    . ARG   C 3 126 ? 44.142  57.727  -37.004 1.00 42.56  ? 419  ARG   A NE    1 
ATOM   1524  C  CZ    . ARG   C 3 126 ? 43.889  56.442  -36.815 1.00 40.25  ? 419  ARG   A CZ    1 
ATOM   1525  N  NH1   . ARG   C 3 126 ? 42.671  56.056  -36.481 1.00 38.54  ? 419  ARG   A NH1   1 
ATOM   1526  N  NH2   . ARG   C 3 126 ? 44.874  55.571  -36.942 1.00 41.00  ? 419  ARG   A NH2   1 
ATOM   1527  N  N     . LEU   C 3 127 ? 40.044  63.322  -38.309 1.00 40.01  ? 420  LEU   A N     1 
ATOM   1528  C  CA    . LEU   C 3 127 ? 39.057  64.302  -37.903 1.00 41.56  ? 420  LEU   A CA    1 
ATOM   1529  C  C     . LEU   C 3 127 ? 38.277  64.818  -39.109 1.00 42.95  ? 420  LEU   A C     1 
ATOM   1530  O  O     . LEU   C 3 127 ? 37.475  65.735  -38.959 1.00 41.10  ? 420  LEU   A O     1 
ATOM   1531  C  CB    . LEU   C 3 127 ? 39.801  65.436  -37.190 1.00 41.87  ? 420  LEU   A CB    1 
ATOM   1532  C  CG    . LEU   C 3 127 ? 39.944  65.296  -35.679 1.00 39.52  ? 420  LEU   A CG    1 
ATOM   1533  C  CD1   . LEU   C 3 127 ? 40.909  66.338  -35.149 1.00 42.52  ? 420  LEU   A CD1   1 
ATOM   1534  C  CD2   . LEU   C 3 127 ? 38.601  65.439  -34.993 1.00 42.89  ? 420  LEU   A CD2   1 
ATOM   1535  N  N     . GLU   C 3 128 ? 38.505  64.254  -40.305 1.00 50.57  ? 421  GLU   A N     1 
ATOM   1536  C  CA    . GLU   C 3 128 ? 37.774  64.714  -41.480 1.00 54.56  ? 421  GLU   A CA    1 
ATOM   1537  C  C     . GLU   C 3 128 ? 36.278  64.452  -41.300 1.00 50.04  ? 421  GLU   A C     1 
ATOM   1538  O  O     . GLU   C 3 128 ? 35.865  63.404  -40.786 1.00 39.32  ? 421  GLU   A O     1 
ATOM   1539  C  CB    . GLU   C 3 128 ? 38.309  64.068  -42.753 1.00 63.72  ? 421  GLU   A CB    1 
ATOM   1540  C  CG    . GLU   C 3 128 ? 39.604  64.719  -43.211 1.00 76.49  ? 421  GLU   A CG    1 
ATOM   1541  C  CD    . GLU   C 3 128 ? 40.138  64.221  -44.546 1.00 82.46  ? 421  GLU   A CD    1 
ATOM   1542  O  OE1   . GLU   C 3 128 ? 39.375  63.534  -45.278 1.00 76.23  ? 421  GLU   A OE1   1 
ATOM   1543  O  OE2   . GLU   C 3 128 ? 41.323  64.517  -44.843 1.00 74.88  ? 421  GLU   A OE2   1 
ATOM   1544  N  N     . GLY   C 3 129 ? 35.476  65.460  -41.667 1.00 42.07  ? 422  GLY   A N     1 
ATOM   1545  C  CA    . GLY   C 3 129 ? 34.034  65.372  -41.492 1.00 42.07  ? 422  GLY   A CA    1 
ATOM   1546  C  C     . GLY   C 3 129 ? 33.544  65.821  -40.111 1.00 41.35  ? 422  GLY   A C     1 
ATOM   1547  O  O     . GLY   C 3 129 ? 32.341  66.003  -39.935 1.00 40.90  ? 422  GLY   A O     1 
ATOM   1548  N  N     . GLU   C 3 130 ? 34.463  65.973  -39.137 1.00 40.75  ? 423  GLU   A N     1 
ATOM   1549  C  CA    . GLU   C 3 130 ? 34.121  66.378  -37.780 1.00 38.24  ? 423  GLU   A CA    1 
ATOM   1550  C  C     . GLU   C 3 130 ? 34.255  67.898  -37.682 1.00 35.86  ? 423  GLU   A C     1 
ATOM   1551  O  O     . GLU   C 3 130 ? 35.152  68.421  -37.036 1.00 36.59  ? 423  GLU   A O     1 
ATOM   1552  C  CB    . GLU   C 3 130 ? 35.011  65.654  -36.758 1.00 40.27  ? 423  GLU   A CB    1 
ATOM   1553  C  CG    . GLU   C 3 130 ? 34.767  64.149  -36.668 1.00 38.82  ? 423  GLU   A CG    1 
ATOM   1554  C  CD    . GLU   C 3 130 ? 33.416  63.773  -36.078 1.00 43.32  ? 423  GLU   A CD    1 
ATOM   1555  O  OE1   . GLU   C 3 130 ? 32.636  64.688  -35.715 1.00 43.93  ? 423  GLU   A OE1   1 
ATOM   1556  O  OE2   . GLU   C 3 130 ? 33.162  62.560  -35.923 1.00 50.09  ? 423  GLU   A OE2   1 
ATOM   1557  N  N     . GLU   C 3 131 ? 33.324  68.600  -38.316 1.00 34.16  ? 424  GLU   A N     1 
ATOM   1558  C  CA    . GLU   C 3 131 ? 33.489  70.012  -38.583 1.00 39.20  ? 424  GLU   A CA    1 
ATOM   1559  C  C     . GLU   C 3 131 ? 33.434  70.864  -37.302 1.00 37.64  ? 424  GLU   A C     1 
ATOM   1560  O  O     . GLU   C 3 131 ? 34.127  71.889  -37.218 1.00 36.77  ? 424  GLU   A O     1 
ATOM   1561  C  CB    . GLU   C 3 131 ? 32.454  70.415  -39.630 1.00 44.45  ? 424  GLU   A CB    1 
ATOM   1562  C  CG    . GLU   C 3 131 ? 32.670  71.827  -40.111 1.00 53.91  ? 424  GLU   A CG    1 
ATOM   1563  C  CD    . GLU   C 3 131 ? 34.118  72.059  -40.517 1.00 62.29  ? 424  GLU   A CD    1 
ATOM   1564  O  OE1   . GLU   C 3 131 ? 34.587  71.257  -41.415 1.00 54.72  ? 424  GLU   A OE1   1 
ATOM   1565  O  OE2   . GLU   C 3 131 ? 34.787  72.987  -39.893 1.00 43.85  ? 424  GLU   A OE2   1 
ATOM   1566  N  N     . ARG   C 3 132 ? 32.635  70.454  -36.299 1.00 34.55  ? 425  ARG   A N     1 
ATOM   1567  C  CA    . ARG   C 3 132 ? 32.552  71.205  -35.048 1.00 35.04  ? 425  ARG   A CA    1 
ATOM   1568  C  C     . ARG   C 3 132 ? 33.808  70.986  -34.198 1.00 31.54  ? 425  ARG   A C     1 
ATOM   1569  O  O     . ARG   C 3 132 ? 34.291  71.929  -33.573 1.00 28.97  ? 425  ARG   A O     1 
ATOM   1570  C  CB    . ARG   C 3 132 ? 31.260  70.894  -34.278 1.00 35.88  ? 425  ARG   A CB    1 
ATOM   1571  C  CG    . ARG   C 3 132 ? 29.984  71.307  -35.011 1.00 37.23  ? 425  ARG   A CG    1 
ATOM   1572  C  CD    . ARG   C 3 132 ? 28.789  71.519  -34.098 1.00 36.66  ? 425  ARG   A CD    1 
ATOM   1573  N  NE    . ARG   C 3 132 ? 28.336  70.290  -33.462 1.00 36.85  ? 425  ARG   A NE    1 
ATOM   1574  C  CZ    . ARG   C 3 132 ? 27.577  70.237  -32.365 1.00 37.13  ? 425  ARG   A CZ    1 
ATOM   1575  N  NH1   . ARG   C 3 132 ? 27.176  71.350  -31.782 1.00 32.41  ? 425  ARG   A NH1   1 
ATOM   1576  N  NH2   . ARG   C 3 132 ? 27.253  69.071  -31.827 1.00 36.68  ? 425  ARG   A NH2   1 
ATOM   1577  N  N     . LEU   C 3 133 ? 34.363  69.763  -34.197 1.00 30.30  ? 426  LEU   A N     1 
ATOM   1578  C  CA    . LEU   C 3 133 ? 35.643  69.527  -33.531 1.00 30.55  ? 426  LEU   A CA    1 
ATOM   1579  C  C     . LEU   C 3 133 ? 36.757  70.341  -34.191 1.00 28.57  ? 426  LEU   A C     1 
ATOM   1580  O  O     . LEU   C 3 133 ? 37.605  70.903  -33.507 1.00 29.31  ? 426  LEU   A O     1 
ATOM   1581  C  CB    . LEU   C 3 133 ? 36.004  68.038  -33.557 1.00 31.01  ? 426  LEU   A CB    1 
ATOM   1582  C  CG    . LEU   C 3 133 ? 35.110  67.106  -32.748 1.00 31.80  ? 426  LEU   A CG    1 
ATOM   1583  C  CD1   . LEU   C 3 133 ? 35.663  65.688  -32.784 1.00 33.08  ? 426  LEU   A CD1   1 
ATOM   1584  C  CD2   . LEU   C 3 133 ? 34.957  67.573  -31.315 1.00 34.38  ? 426  LEU   A CD2   1 
ATOM   1585  N  N     . LEU   C 3 134 ? 36.753  70.439  -35.519 1.00 29.19  ? 427  LEU   A N     1 
ATOM   1586  C  CA    . LEU   C 3 134 ? 37.772  71.223  -36.217 1.00 31.66  ? 427  LEU   A CA    1 
ATOM   1587  C  C     . LEU   C 3 134 ? 37.622  72.725  -35.939 1.00 28.80  ? 427  LEU   A C     1 
ATOM   1588  O  O     . LEU   C 3 134 ? 38.618  73.439  -35.853 1.00 32.82  ? 427  LEU   A O     1 
ATOM   1589  C  CB    . LEU   C 3 134 ? 37.698  70.934  -37.727 1.00 33.39  ? 427  LEU   A CB    1 
ATOM   1590  C  CG    . LEU   C 3 134 ? 38.224  69.567  -38.168 1.00 35.35  ? 427  LEU   A CG    1 
ATOM   1591  C  CD1   . LEU   C 3 134 ? 37.971  69.331  -39.650 1.00 35.55  ? 427  LEU   A CD1   1 
ATOM   1592  C  CD2   . LEU   C 3 134 ? 39.703  69.441  -37.859 1.00 38.30  ? 427  LEU   A CD2   1 
ATOM   1593  N  N     . TRP   C 3 135 ? 36.384  73.212  -35.818 1.00 28.72  ? 428  TRP   A N     1 
ATOM   1594  C  CA    . TRP   C 3 135 ? 36.122  74.592  -35.419 1.00 28.71  ? 428  TRP   A CA    1 
ATOM   1595  C  C     . TRP   C 3 135 ? 36.668  74.855  -34.003 1.00 27.49  ? 428  TRP   A C     1 
ATOM   1596  O  O     . TRP   C 3 135 ? 37.246  75.910  -33.723 1.00 26.95  ? 428  TRP   A O     1 
ATOM   1597  C  CB    . TRP   C 3 135 ? 34.609  74.905  -35.528 1.00 27.50  ? 428  TRP   A CB    1 
ATOM   1598  C  CG    . TRP   C 3 135 ? 34.275  76.350  -35.294 1.00 29.73  ? 428  TRP   A CG    1 
ATOM   1599  C  CD1   . TRP   C 3 135 ? 34.071  77.299  -36.255 1.00 31.37  ? 428  TRP   A CD1   1 
ATOM   1600  C  CD2   . TRP   C 3 135 ? 34.118  77.033  -34.029 1.00 28.96  ? 428  TRP   A CD2   1 
ATOM   1601  N  NE1   . TRP   C 3 135 ? 33.822  78.521  -35.683 1.00 31.95  ? 428  TRP   A NE1   1 
ATOM   1602  C  CE2   . TRP   C 3 135 ? 33.842  78.391  -34.319 1.00 30.17  ? 428  TRP   A CE2   1 
ATOM   1603  C  CE3   . TRP   C 3 135 ? 34.149  76.636  -32.684 1.00 27.77  ? 428  TRP   A CE3   1 
ATOM   1604  C  CZ2   . TRP   C 3 135 ? 33.616  79.345  -33.324 1.00 28.29  ? 428  TRP   A CZ2   1 
ATOM   1605  C  CZ3   . TRP   C 3 135 ? 33.944  77.583  -31.700 1.00 28.10  ? 428  TRP   A CZ3   1 
ATOM   1606  C  CH2   . TRP   C 3 135 ? 33.676  78.916  -32.016 1.00 27.89  ? 428  TRP   A CH2   1 
ATOM   1607  N  N     . LEU   C 3 136 ? 36.478  73.905  -33.079 1.00 28.36  ? 429  LEU   A N     1 
ATOM   1608  C  CA    . LEU   C 3 136 ? 37.016  74.061  -31.730 1.00 27.94  ? 429  LEU   A CA    1 
ATOM   1609  C  C     . LEU   C 3 136 ? 38.530  74.136  -31.784 1.00 27.75  ? 429  LEU   A C     1 
ATOM   1610  O  O     . LEU   C 3 136 ? 39.127  74.906  -31.050 1.00 31.74  ? 429  LEU   A O     1 
ATOM   1611  C  CB    . LEU   C 3 136 ? 36.587  72.897  -30.844 1.00 27.66  ? 429  LEU   A CB    1 
ATOM   1612  C  CG    . LEU   C 3 136 ? 35.152  72.963  -30.348 1.00 29.67  ? 429  LEU   A CG    1 
ATOM   1613  C  CD1   . LEU   C 3 136 ? 34.776  71.670  -29.666 1.00 32.66  ? 429  LEU   A CD1   1 
ATOM   1614  C  CD2   . LEU   C 3 136 ? 34.962  74.122  -29.388 1.00 32.49  ? 429  LEU   A CD2   1 
ATOM   1615  N  N     . TYR   C 3 137 ? 39.137  73.315  -32.641 1.00 29.15  ? 430  TYR   A N     1 
ATOM   1616  C  CA    . TYR   C 3 137 ? 40.572  73.328  -32.824 1.00 29.53  ? 430  TYR   A CA    1 
ATOM   1617  C  C     . TYR   C 3 137 ? 41.021  74.712  -33.294 1.00 31.85  ? 430  TYR   A C     1 
ATOM   1618  O  O     . TYR   C 3 137 ? 41.884  75.353  -32.683 1.00 32.65  ? 430  TYR   A O     1 
ATOM   1619  C  CB    . TYR   C 3 137 ? 41.008  72.241  -33.813 1.00 30.22  ? 430  TYR   A CB    1 
ATOM   1620  C  CG    . TYR   C 3 137 ? 42.501  72.228  -34.023 1.00 30.69  ? 430  TYR   A CG    1 
ATOM   1621  C  CD1   . TYR   C 3 137 ? 43.358  71.806  -33.018 1.00 28.64  ? 430  TYR   A CD1   1 
ATOM   1622  C  CD2   . TYR   C 3 137 ? 43.065  72.750  -35.173 1.00 31.30  ? 430  TYR   A CD2   1 
ATOM   1623  C  CE1   . TYR   C 3 137 ? 44.731  71.825  -33.184 1.00 28.44  ? 430  TYR   A CE1   1 
ATOM   1624  C  CE2   . TYR   C 3 137 ? 44.441  72.784  -35.354 1.00 30.13  ? 430  TYR   A CE2   1 
ATOM   1625  C  CZ    . TYR   C 3 137 ? 45.272  72.323  -34.354 1.00 28.76  ? 430  TYR   A CZ    1 
ATOM   1626  O  OH    . TYR   C 3 137 ? 46.623  72.383  -34.523 1.00 29.83  ? 430  TYR   A OH    1 
ATOM   1627  N  N     . ARG   C 3 138 ? 40.452  75.170  -34.407 1.00 35.05  ? 431  ARG   A N     1 
ATOM   1628  C  CA    . ARG   C 3 138 ? 40.955  76.372  -35.061 1.00 34.95  ? 431  ARG   A CA    1 
ATOM   1629  C  C     . ARG   C 3 138 ? 40.606  77.619  -34.253 1.00 33.43  ? 431  ARG   A C     1 
ATOM   1630  O  O     . ARG   C 3 138 ? 41.406  78.555  -34.174 1.00 31.30  ? 431  ARG   A O     1 
ATOM   1631  C  CB    . ARG   C 3 138 ? 40.353  76.531  -36.459 1.00 39.46  ? 431  ARG   A CB    1 
ATOM   1632  C  CG    . ARG   C 3 138 ? 40.850  75.535  -37.495 1.00 43.64  ? 431  ARG   A CG    1 
ATOM   1633  C  CD    . ARG   C 3 138 ? 40.487  75.987  -38.913 1.00 46.68  ? 431  ARG   A CD    1 
ATOM   1634  N  NE    . ARG   C 3 138 ? 39.508  75.159  -39.604 1.00 47.52  ? 431  ARG   A NE    1 
ATOM   1635  C  CZ    . ARG   C 3 138 ? 38.205  75.129  -39.349 1.00 48.76  ? 431  ARG   A CZ    1 
ATOM   1636  N  NH1   . ARG   C 3 138 ? 37.550  73.998  -39.511 1.00 50.57  ? 431  ARG   A NH1   1 
ATOM   1637  N  NH2   . ARG   C 3 138 ? 37.563  76.207  -38.927 1.00 49.17  ? 431  ARG   A NH2   1 
ATOM   1638  N  N     . GLU   C 3 139 ? 39.375  77.670  -33.720 1.00 31.87  ? 432  GLU   A N     1 
ATOM   1639  C  CA    . GLU   C 3 139 ? 38.864  78.906  -33.151 1.00 31.97  ? 432  GLU   A CA    1 
ATOM   1640  C  C     . GLU   C 3 139 ? 38.994  78.944  -31.631 1.00 34.92  ? 432  GLU   A C     1 
ATOM   1641  O  O     . GLU   C 3 139 ? 38.830  80.011  -31.054 1.00 41.05  ? 432  GLU   A O     1 
ATOM   1642  C  CB    . GLU   C 3 139 ? 37.404  79.116  -33.542 1.00 33.09  ? 432  GLU   A CB    1 
ATOM   1643  C  CG    . GLU   C 3 139 ? 37.188  79.191  -35.043 1.00 34.56  ? 432  GLU   A CG    1 
ATOM   1644  C  CD    . GLU   C 3 139 ? 37.921  80.324  -35.739 1.00 34.40  ? 432  GLU   A CD    1 
ATOM   1645  O  OE1   . GLU   C 3 139 ? 38.123  81.371  -35.096 1.00 40.05  ? 432  GLU   A OE1   1 
ATOM   1646  O  OE2   . GLU   C 3 139 ? 38.280  80.164  -36.911 1.00 38.07  ? 432  GLU   A OE2   1 
ATOM   1647  N  N     . VAL   C 3 140 ? 39.265  77.807  -30.972 1.00 34.19  ? 433  VAL   A N     1 
ATOM   1648  C  CA    . VAL   C 3 140 ? 39.355  77.813  -29.521 1.00 30.44  ? 433  VAL   A CA    1 
ATOM   1649  C  C     . VAL   C 3 140 ? 40.696  77.254  -29.052 1.00 29.63  ? 433  VAL   A C     1 
ATOM   1650  O  O     . VAL   C 3 140 ? 41.464  77.987  -28.419 1.00 32.37  ? 433  VAL   A O     1 
ATOM   1651  C  CB    . VAL   C 3 140 ? 38.161  77.103  -28.869 1.00 28.32  ? 433  VAL   A CB    1 
ATOM   1652  C  CG1   . VAL   C 3 140 ? 38.320  77.023  -27.362 1.00 30.81  ? 433  VAL   A CG1   1 
ATOM   1653  C  CG2   . VAL   C 3 140 ? 36.860  77.789  -29.211 1.00 27.89  ? 433  VAL   A CG2   1 
ATOM   1654  N  N     . GLU   C 3 141 ? 40.987  75.983  -29.360 1.00 28.31  ? 434  GLU   A N     1 
ATOM   1655  C  CA    . GLU   C 3 141 ? 42.083  75.291  -28.692 1.00 29.62  ? 434  GLU   A CA    1 
ATOM   1656  C  C     . GLU   C 3 141 ? 43.441  75.815  -29.150 1.00 29.14  ? 434  GLU   A C     1 
ATOM   1657  O  O     . GLU   C 3 141 ? 44.308  76.089  -28.329 1.00 31.69  ? 434  GLU   A O     1 
ATOM   1658  C  CB    . GLU   C 3 141 ? 41.991  73.778  -28.879 1.00 30.17  ? 434  GLU   A CB    1 
ATOM   1659  C  CG    . GLU   C 3 141 ? 40.803  73.141  -28.161 1.00 29.35  ? 434  GLU   A CG    1 
ATOM   1660  C  CD    . GLU   C 3 141 ? 40.742  73.222  -26.642 1.00 31.84  ? 434  GLU   A CD    1 
ATOM   1661  O  OE1   . GLU   C 3 141 ? 41.702  73.756  -26.015 1.00 32.28  ? 434  GLU   A OE1   1 
ATOM   1662  O  OE2   . GLU   C 3 141 ? 39.732  72.718  -26.075 1.00 29.65  ? 434  GLU   A OE2   1 
ATOM   1663  N  N     . ARG   C 3 142 ? 43.624  75.966  -30.456 1.00 32.57  ? 435  ARG   A N     1 
ATOM   1664  C  CA    . ARG   C 3 142 ? 44.908  76.393  -30.987 1.00 31.97  ? 435  ARG   A CA    1 
ATOM   1665  C  C     . ARG   C 3 142 ? 45.216  77.815  -30.517 1.00 31.60  ? 435  ARG   A C     1 
ATOM   1666  O  O     . ARG   C 3 142 ? 46.275  78.044  -29.925 1.00 32.00  ? 435  ARG   A O     1 
ATOM   1667  C  CB    . ARG   C 3 142 ? 44.960  76.246  -32.512 1.00 32.93  ? 435  ARG   A CB    1 
ATOM   1668  C  CG    . ARG   C 3 142 ? 46.322  76.589  -33.095 1.00 35.63  ? 435  ARG   A CG    1 
ATOM   1669  C  CD    . ARG   C 3 142 ? 46.472  76.286  -34.565 1.00 36.59  ? 435  ARG   A CD    1 
ATOM   1670  N  NE    . ARG   C 3 142 ? 45.565  77.067  -35.387 1.00 39.27  ? 435  ARG   A NE    1 
ATOM   1671  C  CZ    . ARG   C 3 142 ? 45.249  76.762  -36.643 1.00 42.62  ? 435  ARG   A CZ    1 
ATOM   1672  N  NH1   . ARG   C 3 142 ? 45.801  75.720  -37.240 1.00 37.87  ? 435  ARG   A NH1   1 
ATOM   1673  N  NH2   . ARG   C 3 142 ? 44.336  77.475  -37.274 1.00 42.35  ? 435  ARG   A NH2   1 
ATOM   1674  N  N     . PRO   C 3 143 ? 44.341  78.829  -30.739 1.00 30.16  ? 436  PRO   A N     1 
ATOM   1675  C  CA    . PRO   C 3 143 ? 44.630  80.168  -30.230 1.00 28.29  ? 436  PRO   A CA    1 
ATOM   1676  C  C     . PRO   C 3 143 ? 44.741  80.253  -28.702 1.00 30.35  ? 436  PRO   A C     1 
ATOM   1677  O  O     . PRO   C 3 143 ? 45.510  81.078  -28.187 1.00 29.11  ? 436  PRO   A O     1 
ATOM   1678  C  CB    . PRO   C 3 143 ? 43.511  81.047  -30.812 1.00 28.55  ? 436  PRO   A CB    1 
ATOM   1679  C  CG    . PRO   C 3 143 ? 42.449  80.110  -31.314 1.00 28.85  ? 436  PRO   A CG    1 
ATOM   1680  C  CD    . PRO   C 3 143 ? 43.130  78.783  -31.565 1.00 28.23  ? 436  PRO   A CD    1 
ATOM   1681  N  N     . LEU   C 3 144 ? 44.025  79.376  -27.981 1.00 28.87  ? 437  LEU   A N     1 
ATOM   1682  C  CA    . LEU   C 3 144 ? 44.105  79.358  -26.526 1.00 29.85  ? 437  LEU   A CA    1 
ATOM   1683  C  C     . LEU   C 3 144 ? 45.486  78.941  -26.057 1.00 29.30  ? 437  LEU   A C     1 
ATOM   1684  O  O     . LEU   C 3 144 ? 45.925  79.384  -24.999 1.00 29.40  ? 437  LEU   A O     1 
ATOM   1685  C  CB    . LEU   C 3 144 ? 43.073  78.396  -25.935 1.00 31.47  ? 437  LEU   A CB    1 
ATOM   1686  C  CG    . LEU   C 3 144 ? 43.050  78.307  -24.405 1.00 31.23  ? 437  LEU   A CG    1 
ATOM   1687  C  CD1   . LEU   C 3 144 ? 42.561  79.603  -23.792 1.00 32.31  ? 437  LEU   A CD1   1 
ATOM   1688  C  CD2   . LEU   C 3 144 ? 42.177  77.154  -23.939 1.00 31.32  ? 437  LEU   A CD2   1 
ATOM   1689  N  N     . SER   C 3 145 ? 46.131  78.039  -26.809 1.00 34.12  ? 438  SER   A N     1 
ATOM   1690  C  CA    . SER   C 3 145 ? 47.441  77.541  -26.423 1.00 30.88  ? 438  SER   A CA    1 
ATOM   1691  C  C     . SER   C 3 145 ? 48.399  78.723  -26.290 1.00 29.77  ? 438  SER   A C     1 
ATOM   1692  O  O     . SER   C 3 145 ? 49.227  78.745  -25.384 1.00 33.41  ? 438  SER   A O     1 
ATOM   1693  C  CB    . SER   C 3 145 ? 47.940  76.444  -27.357 1.00 30.47  ? 438  SER   A CB    1 
ATOM   1694  O  OG    . SER   C 3 145 ? 48.263  76.923  -28.653 1.00 29.02  ? 438  SER   A OG    1 
ATOM   1695  N  N     . ALA   C 3 146 ? 48.244  79.730  -27.162 1.00 30.71  ? 439  ALA   A N     1 
ATOM   1696  C  CA    . ALA   C 3 146 ? 49.056  80.936  -27.114 1.00 31.06  ? 439  ALA   A CA    1 
ATOM   1697  C  C     . ALA   C 3 146 ? 48.736  81.772  -25.880 1.00 31.16  ? 439  ALA   A C     1 
ATOM   1698  O  O     . ALA   C 3 146 ? 49.630  82.394  -25.299 1.00 33.58  ? 439  ALA   A O     1 
ATOM   1699  C  CB    . ALA   C 3 146 ? 48.842  81.753  -28.357 1.00 34.86  ? 439  ALA   A CB    1 
ATOM   1700  N  N     . VAL   C 3 147 ? 47.450  81.848  -25.532 1.00 31.40  ? 440  VAL   A N     1 
ATOM   1701  C  CA    . VAL   C 3 147 ? 47.037  82.540  -24.322 1.00 30.16  ? 440  VAL   A CA    1 
ATOM   1702  C  C     . VAL   C 3 147 ? 47.687  81.855  -23.117 1.00 32.34  ? 440  VAL   A C     1 
ATOM   1703  O  O     . VAL   C 3 147 ? 48.238  82.526  -22.245 1.00 32.36  ? 440  VAL   A O     1 
ATOM   1704  C  CB    . VAL   C 3 147 ? 45.501  82.584  -24.204 1.00 30.24  ? 440  VAL   A CB    1 
ATOM   1705  C  CG1   . VAL   C 3 147 ? 45.051  83.205  -22.891 1.00 28.65  ? 440  VAL   A CG1   1 
ATOM   1706  C  CG2   . VAL   C 3 147 ? 44.871  83.313  -25.397 1.00 31.12  ? 440  VAL   A CG2   1 
ATOM   1707  N  N     . LEU   C 3 148 ? 47.630  80.515  -23.064 1.00 29.98  ? 441  LEU   A N     1 
ATOM   1708  C  CA    . LEU   C 3 148 ? 48.116  79.793  -21.897 1.00 30.13  ? 441  LEU   A CA    1 
ATOM   1709  C  C     . LEU   C 3 148 ? 49.630  79.971  -21.748 1.00 34.95  ? 441  LEU   A C     1 
ATOM   1710  O  O     . LEU   C 3 148 ? 50.134  80.083  -20.627 1.00 35.26  ? 441  LEU   A O     1 
ATOM   1711  C  CB    . LEU   C 3 148 ? 47.751  78.315  -22.038 1.00 30.35  ? 441  LEU   A CB    1 
ATOM   1712  C  CG    . LEU   C 3 148 ? 46.260  77.978  -22.042 1.00 26.79  ? 441  LEU   A CG    1 
ATOM   1713  C  CD1   . LEU   C 3 148 ? 46.073  76.479  -22.089 1.00 24.86  ? 441  LEU   A CD1   1 
ATOM   1714  C  CD2   . LEU   C 3 148 ? 45.563  78.554  -20.815 1.00 29.13  ? 441  LEU   A CD2   1 
ATOM   1715  N  N     . ALA   C 3 149 ? 50.342  80.023  -22.886 1.00 34.25  ? 442  ALA   A N     1 
ATOM   1716  C  CA    . ALA   C 3 149 ? 51.777  80.255  -22.900 1.00 35.83  ? 442  ALA   A CA    1 
ATOM   1717  C  C     . ALA   C 3 149 ? 52.106  81.572  -22.203 1.00 34.06  ? 442  ALA   A C     1 
ATOM   1718  O  O     . ALA   C 3 149 ? 52.994  81.635  -21.363 1.00 34.50  ? 442  ALA   A O     1 
ATOM   1719  C  CB    . ALA   C 3 149 ? 52.287  80.238  -24.318 1.00 37.77  ? 442  ALA   A CB    1 
ATOM   1720  N  N     . HIS   C 3 150 ? 51.380  82.634  -22.527 1.00 34.69  ? 443  HIS   A N     1 
ATOM   1721  C  CA    . HIS   C 3 150 ? 51.629  83.908  -21.869 1.00 34.15  ? 443  HIS   A CA    1 
ATOM   1722  C  C     . HIS   C 3 150 ? 51.330  83.816  -20.374 1.00 36.48  ? 443  HIS   A C     1 
ATOM   1723  O  O     . HIS   C 3 150 ? 52.049  84.388  -19.561 1.00 40.19  ? 443  HIS   A O     1 
ATOM   1724  C  CB    . HIS   C 3 150 ? 50.840  85.021  -22.565 1.00 38.96  ? 443  HIS   A CB    1 
ATOM   1725  C  CG    . HIS   C 3 150 ? 51.481  85.493  -23.840 1.00 41.92  ? 443  HIS   A CG    1 
ATOM   1726  N  ND1   . HIS   C 3 150 ? 51.028  85.165  -25.098 1.00 47.25  ? 443  HIS   A ND1   1 
ATOM   1727  C  CD2   . HIS   C 3 150 ? 52.610  86.243  -24.010 1.00 45.78  ? 443  HIS   A CD2   1 
ATOM   1728  C  CE1   . HIS   C 3 150 ? 51.813  85.743  -26.009 1.00 48.24  ? 443  HIS   A CE1   1 
ATOM   1729  N  NE2   . HIS   C 3 150 ? 52.807  86.411  -25.356 1.00 46.19  ? 443  HIS   A NE2   1 
ATOM   1730  N  N     . MET   C 3 151 ? 50.266  83.093  -20.013 1.00 35.22  ? 444  MET   A N     1 
ATOM   1731  C  CA    . MET   C 3 151 ? 49.808  83.065  -18.644 1.00 31.84  ? 444  MET   A CA    1 
ATOM   1732  C  C     . MET   C 3 151 ? 50.874  82.381  -17.796 1.00 33.61  ? 444  MET   A C     1 
ATOM   1733  O  O     . MET   C 3 151 ? 51.269  82.882  -16.745 1.00 34.82  ? 444  MET   A O     1 
ATOM   1734  C  CB    . MET   C 3 151 ? 48.478  82.310  -18.539 1.00 32.51  ? 444  MET   A CB    1 
ATOM   1735  C  CG    . MET   C 3 151 ? 47.289  83.121  -19.033 1.00 32.95  ? 444  MET   A CG    1 
ATOM   1736  S  SD    . MET   C 3 151 ? 45.752  82.188  -19.095 1.00 31.26  ? 444  MET   A SD    1 
ATOM   1737  C  CE    . MET   C 3 151 ? 45.360  82.004  -17.358 1.00 30.81  ? 444  MET   A CE    1 
ATOM   1738  N  N     . GLU   C 3 152 ? 51.337  81.231  -18.284 1.00 35.23  ? 445  GLU   A N     1 
ATOM   1739  C  CA    . GLU   C 3 152 ? 52.379  80.458  -17.631 1.00 35.10  ? 445  GLU   A CA    1 
ATOM   1740  C  C     . GLU   C 3 152 ? 53.656  81.270  -17.437 1.00 36.76  ? 445  GLU   A C     1 
ATOM   1741  O  O     . GLU   C 3 152 ? 54.253  81.195  -16.366 1.00 40.75  ? 445  GLU   A O     1 
ATOM   1742  C  CB    . GLU   C 3 152 ? 52.727  79.219  -18.449 1.00 35.62  ? 445  GLU   A CB    1 
ATOM   1743  C  CG    . GLU   C 3 152 ? 51.613  78.199  -18.465 1.00 36.81  ? 445  GLU   A CG    1 
ATOM   1744  C  CD    . GLU   C 3 152 ? 51.979  76.785  -18.875 1.00 39.04  ? 445  GLU   A CD    1 
ATOM   1745  O  OE1   . GLU   C 3 152 ? 53.192  76.428  -18.904 1.00 38.11  ? 445  GLU   A OE1   1 
ATOM   1746  O  OE2   . GLU   C 3 152 ? 51.036  76.026  -19.112 1.00 37.07  ? 445  GLU   A OE2   1 
ATOM   1747  N  N     . ALA   C 3 153 ? 54.103  81.981  -18.479 1.00 36.83  ? 446  ALA   A N     1 
ATOM   1748  C  CA    . ALA   C 3 153 ? 55.387  82.686  -18.449 1.00 38.72  ? 446  ALA   A CA    1 
ATOM   1749  C  C     . ALA   C 3 153 ? 55.308  83.987  -17.632 1.00 41.18  ? 446  ALA   A C     1 
ATOM   1750  O  O     . ALA   C 3 153 ? 56.333  84.509  -17.187 1.00 37.78  ? 446  ALA   A O     1 
ATOM   1751  C  CB    . ALA   C 3 153 ? 55.855  82.951  -19.861 1.00 35.93  ? 446  ALA   A CB    1 
ATOM   1752  N  N     . THR   C 3 154 ? 54.092  84.509  -17.419 1.00 38.78  ? 447  THR   A N     1 
ATOM   1753  C  CA    . THR   C 3 154 ? 53.899  85.741  -16.670 1.00 36.16  ? 447  THR   A CA    1 
ATOM   1754  C  C     . THR   C 3 154 ? 53.948  85.457  -15.171 1.00 36.27  ? 447  THR   A C     1 
ATOM   1755  O  O     . THR   C 3 154 ? 54.558  86.207  -14.416 1.00 42.68  ? 447  THR   A O     1 
ATOM   1756  C  CB    . THR   C 3 154 ? 52.557  86.407  -17.018 1.00 36.51  ? 447  THR   A CB    1 
ATOM   1757  O  OG1   . THR   C 3 154 ? 52.517  86.688  -18.418 1.00 32.27  ? 447  THR   A OG1   1 
ATOM   1758  C  CG2   . THR   C 3 154 ? 52.319  87.685  -16.242 1.00 35.12  ? 447  THR   A CG2   1 
ATOM   1759  N  N     . GLY   C 3 155 ? 53.265  84.401  -14.725 1.00 35.99  ? 448  GLY   A N     1 
ATOM   1760  C  CA    . GLY   C 3 155 ? 53.192  84.087  -13.306 1.00 35.98  ? 448  GLY   A CA    1 
ATOM   1761  C  C     . GLY   C 3 155 ? 52.431  85.129  -12.475 1.00 36.12  ? 448  GLY   A C     1 
ATOM   1762  O  O     . GLY   C 3 155 ? 51.817  86.062  -13.004 1.00 37.14  ? 448  GLY   A O     1 
ATOM   1763  N  N     . VAL   C 3 156 ? 52.493  84.946  -11.151 1.00 37.49  ? 449  VAL   A N     1 
ATOM   1764  C  CA    . VAL   C 3 156 ? 51.781  85.765  -10.180 1.00 38.65  ? 449  VAL   A CA    1 
ATOM   1765  C  C     . VAL   C 3 156 ? 52.730  86.092  -9.022  1.00 40.95  ? 449  VAL   A C     1 
ATOM   1766  O  O     . VAL   C 3 156 ? 53.474  85.237  -8.546  1.00 37.06  ? 449  VAL   A O     1 
ATOM   1767  C  CB    . VAL   C 3 156 ? 50.506  85.070  -9.652  1.00 40.34  ? 449  VAL   A CB    1 
ATOM   1768  C  CG1   . VAL   C 3 156 ? 50.797  83.739  -8.981  1.00 41.53  ? 449  VAL   A CG1   1 
ATOM   1769  C  CG2   . VAL   C 3 156 ? 49.739  85.959  -8.674  1.00 46.64  ? 449  VAL   A CG2   1 
ATOM   1770  N  N     . ARG   C 3 157 ? 52.663  87.338  -8.545  1.00 39.67  ? 450  ARG   A N     1 
ATOM   1771  C  CA    . ARG   C 3 157 ? 53.457  87.774  -7.417  1.00 41.16  ? 450  ARG   A CA    1 
ATOM   1772  C  C     . ARG   C 3 157 ? 52.886  87.220  -6.115  1.00 42.46  ? 450  ARG   A C     1 
ATOM   1773  O  O     . ARG   C 3 157 ? 51.674  87.091  -5.943  1.00 42.26  ? 450  ARG   A O     1 
ATOM   1774  C  CB    . ARG   C 3 157 ? 53.486  89.305  -7.391  1.00 46.33  ? 450  ARG   A CB    1 
ATOM   1775  C  CG    . ARG   C 3 157 ? 54.499  89.879  -6.412  1.00 51.79  ? 450  ARG   A CG    1 
ATOM   1776  C  CD    . ARG   C 3 157 ? 54.489  91.398  -6.411  1.00 55.25  ? 450  ARG   A CD    1 
ATOM   1777  N  NE    . ARG   C 3 157 ? 55.342  91.990  -5.379  1.00 56.52  ? 450  ARG   A NE    1 
ATOM   1778  C  CZ    . ARG   C 3 157 ? 55.212  93.235  -4.908  1.00 55.75  ? 450  ARG   A CZ    1 
ATOM   1779  N  NH1   . ARG   C 3 157 ? 54.149  93.968  -5.201  1.00 48.86  ? 450  ARG   A NH1   1 
ATOM   1780  N  NH2   . ARG   C 3 157 ? 56.151  93.748  -4.134  1.00 53.88  ? 450  ARG   A NH2   1 
ATOM   1781  N  N     . LEU   C 3 158 ? 53.782  86.998  -5.155  1.00 40.99  ? 451  LEU   A N     1 
ATOM   1782  C  CA    . LEU   C 3 158 ? 53.458  86.391  -3.878  1.00 39.40  ? 451  LEU   A CA    1 
ATOM   1783  C  C     . LEU   C 3 158 ? 54.017  87.270  -2.751  1.00 41.91  ? 451  LEU   A C     1 
ATOM   1784  O  O     . LEU   C 3 158 ? 55.118  87.814  -2.872  1.00 47.46  ? 451  LEU   A O     1 
ATOM   1785  C  CB    . LEU   C 3 158 ? 54.126  85.020  -3.947  1.00 41.51  ? 451  LEU   A CB    1 
ATOM   1786  C  CG    . LEU   C 3 158 ? 53.381  83.853  -3.328  1.00 41.88  ? 451  LEU   A CG    1 
ATOM   1787  C  CD1   . LEU   C 3 158 ? 52.066  83.618  -4.041  1.00 44.49  ? 451  LEU   A CD1   1 
ATOM   1788  C  CD2   . LEU   C 3 158 ? 54.249  82.607  -3.385  1.00 40.71  ? 451  LEU   A CD2   1 
ATOM   1789  N  N     . ASP   C 3 159 ? 53.243  87.467  -1.673  1.00 45.11  ? 452  ASP   A N     1 
ATOM   1790  C  CA    . ASP   C 3 159 ? 53.723  88.178  -0.493  1.00 44.90  ? 452  ASP   A CA    1 
ATOM   1791  C  C     . ASP   C 3 159 ? 54.462  87.183  0.403   1.00 43.73  ? 452  ASP   A C     1 
ATOM   1792  O  O     . ASP   C 3 159 ? 53.845  86.513  1.240   1.00 41.06  ? 452  ASP   A O     1 
ATOM   1793  C  CB    . ASP   C 3 159 ? 52.585  88.865  0.273   1.00 48.51  ? 452  ASP   A CB    1 
ATOM   1794  C  CG    . ASP   C 3 159 ? 53.038  89.820  1.378   1.00 46.98  ? 452  ASP   A CG    1 
ATOM   1795  O  OD1   . ASP   C 3 159 ? 54.206  89.782  1.780   1.00 49.98  ? 452  ASP   A OD1   1 
ATOM   1796  O  OD2   . ASP   C 3 159 ? 52.225  90.631  1.807   1.00 51.80  ? 452  ASP   A OD2   1 
ATOM   1797  N  N     . VAL   C 3 160 ? 55.787  87.116  0.206   1.00 42.56  ? 453  VAL   A N     1 
ATOM   1798  C  CA    . VAL   C 3 160 ? 56.651  86.094  0.787   1.00 48.53  ? 453  VAL   A CA    1 
ATOM   1799  C  C     . VAL   C 3 160 ? 56.718  86.235  2.313   1.00 46.32  ? 453  VAL   A C     1 
ATOM   1800  O  O     . VAL   C 3 160 ? 56.614  85.232  3.013   1.00 44.44  ? 453  VAL   A O     1 
ATOM   1801  C  CB    . VAL   C 3 160 ? 58.063  86.160  0.164   1.00 56.27  ? 453  VAL   A CB    1 
ATOM   1802  C  CG1   . VAL   C 3 160 ? 59.036  85.227  0.875   1.00 60.26  ? 453  VAL   A CG1   1 
ATOM   1803  C  CG2   . VAL   C 3 160 ? 58.051  85.874  -1.334  1.00 52.26  ? 453  VAL   A CG2   1 
ATOM   1804  N  N     . ALA   C 3 161 ? 56.876  87.471  2.819   1.00 40.94  ? 454  ALA   A N     1 
ATOM   1805  C  CA    . ALA   C 3 161 ? 57.076  87.733  4.238   1.00 45.70  ? 454  ALA   A CA    1 
ATOM   1806  C  C     . ALA   C 3 161 ? 55.825  87.368  5.045   1.00 47.04  ? 454  ALA   A C     1 
ATOM   1807  O  O     . ALA   C 3 161 ? 55.898  86.800  6.137   1.00 45.61  ? 454  ALA   A O     1 
ATOM   1808  C  CB    . ALA   C 3 161 ? 57.448  89.193  4.426   1.00 44.63  ? 454  ALA   A CB    1 
ATOM   1809  N  N     . TYR   C 3 162 ? 54.668  87.724  4.479   1.00 47.03  ? 455  TYR   A N     1 
ATOM   1810  C  CA    . TYR   C 3 162 ? 53.364  87.357  5.000   1.00 42.11  ? 455  TYR   A CA    1 
ATOM   1811  C  C     . TYR   C 3 162 ? 53.256  85.839  5.177   1.00 40.93  ? 455  TYR   A C     1 
ATOM   1812  O  O     . TYR   C 3 162 ? 52.823  85.368  6.227   1.00 41.44  ? 455  TYR   A O     1 
ATOM   1813  C  CB    . TYR   C 3 162 ? 52.302  87.909  4.047   1.00 44.44  ? 455  TYR   A CB    1 
ATOM   1814  C  CG    . TYR   C 3 162 ? 50.891  87.642  4.493   1.00 49.46  ? 455  TYR   A CG    1 
ATOM   1815  C  CD1   . TYR   C 3 162 ? 50.238  88.489  5.379   1.00 47.79  ? 455  TYR   A CD1   1 
ATOM   1816  C  CD2   . TYR   C 3 162 ? 50.238  86.495  4.078   1.00 47.59  ? 455  TYR   A CD2   1 
ATOM   1817  C  CE1   . TYR   C 3 162 ? 48.949  88.228  5.809   1.00 48.88  ? 455  TYR   A CE1   1 
ATOM   1818  C  CE2   . TYR   C 3 162 ? 48.953  86.217  4.505   1.00 51.20  ? 455  TYR   A CE2   1 
ATOM   1819  C  CZ    . TYR   C 3 162 ? 48.304  87.084  5.367   1.00 54.12  ? 455  TYR   A CZ    1 
ATOM   1820  O  OH    . TYR   C 3 162 ? 47.025  86.762  5.767   1.00 54.88  ? 455  TYR   A OH    1 
ATOM   1821  N  N     . LEU   C 3 163 ? 53.657  85.071  4.150   1.00 39.74  ? 456  LEU   A N     1 
ATOM   1822  C  CA    . LEU   C 3 163 ? 53.576  83.614  4.199   1.00 40.48  ? 456  LEU   A CA    1 
ATOM   1823  C  C     . LEU   C 3 163 ? 54.540  83.014  5.228   1.00 39.49  ? 456  LEU   A C     1 
ATOM   1824  O  O     . LEU   C 3 163 ? 54.198  82.045  5.897   1.00 39.46  ? 456  LEU   A O     1 
ATOM   1825  C  CB    . LEU   C 3 163 ? 53.863  83.051  2.804   1.00 40.59  ? 456  LEU   A CB    1 
ATOM   1826  C  CG    . LEU   C 3 163 ? 52.689  83.096  1.821   1.00 42.87  ? 456  LEU   A CG    1 
ATOM   1827  C  CD1   . LEU   C 3 163 ? 53.129  82.753  0.411   1.00 46.34  ? 456  LEU   A CD1   1 
ATOM   1828  C  CD2   . LEU   C 3 163 ? 51.589  82.148  2.244   1.00 45.33  ? 456  LEU   A CD2   1 
ATOM   1829  N  N     . ARG   C 3 164 ? 55.764  83.548  5.304   1.00 41.86  ? 457  ARG   A N     1 
ATOM   1830  C  CA    . ARG   C 3 164 ? 56.749  83.141  6.303   1.00 45.47  ? 457  ARG   A CA    1 
ATOM   1831  C  C     . ARG   C 3 164 ? 56.185  83.318  7.724   1.00 40.87  ? 457  ARG   A C     1 
ATOM   1832  O  O     . ARG   C 3 164 ? 56.228  82.408  8.554   1.00 40.12  ? 457  ARG   A O     1 
ATOM   1833  C  CB    . ARG   C 3 164 ? 58.047  83.930  6.078   1.00 43.99  ? 457  ARG   A CB    1 
ATOM   1834  C  CG    . ARG   C 3 164 ? 59.134  83.172  5.323   1.00 41.24  ? 457  ARG   A CG    1 
ATOM   1835  C  CD    . ARG   C 3 164 ? 59.199  83.071  3.805   1.00 39.73  ? 457  ARG   A CD    1 
ATOM   1836  N  NE    . ARG   C 3 164 ? 59.836  81.776  3.560   1.00 36.40  ? 457  ARG   A NE    1 
ATOM   1837  C  CZ    . ARG   C 3 164 ? 60.145  81.188  2.410   1.00 35.09  ? 457  ARG   A CZ    1 
ATOM   1838  N  NH1   . ARG   C 3 164 ? 60.770  81.802  1.425   1.00 34.14  ? 457  ARG   A NH1   1 
ATOM   1839  N  NH2   . ARG   C 3 164 ? 59.943  79.890  2.321   1.00 39.44  ? 457  ARG   A NH2   1 
ATOM   1840  N  N     . ALA   C 3 165 ? 55.597  84.483  7.998   1.00 38.70  ? 458  ALA   A N     1 
ATOM   1841  C  CA    . ALA   C 3 165 ? 54.991  84.744  9.297   1.00 40.03  ? 458  ALA   A CA    1 
ATOM   1842  C  C     . ALA   C 3 165 ? 53.842  83.767  9.561   1.00 42.32  ? 458  ALA   A C     1 
ATOM   1843  O  O     . ALA   C 3 165 ? 53.658  83.315  10.690  1.00 44.93  ? 458  ALA   A O     1 
ATOM   1844  C  CB    . ALA   C 3 165 ? 54.534  86.196  9.362   1.00 36.47  ? 458  ALA   A CB    1 
ATOM   1845  N  N     . LEU   C 3 166 ? 53.063  83.436  8.521   1.00 42.23  ? 459  LEU   A N     1 
ATOM   1846  C  CA    . LEU   C 3 166 ? 51.923  82.540  8.670   1.00 42.27  ? 459  LEU   A CA    1 
ATOM   1847  C  C     . LEU   C 3 166 ? 52.381  81.108  8.970   1.00 38.14  ? 459  LEU   A C     1 
ATOM   1848  O  O     . LEU   C 3 166 ? 51.711  80.396  9.733   1.00 39.43  ? 459  LEU   A O     1 
ATOM   1849  C  CB    . LEU   C 3 166 ? 51.074  82.636  7.392   1.00 46.36  ? 459  LEU   A CB    1 
ATOM   1850  C  CG    . LEU   C 3 166 ? 49.740  81.888  7.379   1.00 44.37  ? 459  LEU   A CG    1 
ATOM   1851  C  CD1   . LEU   C 3 166 ? 48.832  82.362  8.496   1.00 48.27  ? 459  LEU   A CD1   1 
ATOM   1852  C  CD2   . LEU   C 3 166 ? 49.051  82.067  6.035   1.00 49.39  ? 459  LEU   A CD2   1 
ATOM   1853  N  N     . SER   C 3 167 ? 53.502  80.676  8.369   1.00 34.65  ? 460  SER   A N     1 
ATOM   1854  C  CA    . SER   C 3 167 ? 54.072  79.356  8.655   1.00 38.37  ? 460  SER   A CA    1 
ATOM   1855  C  C     . SER   C 3 167 ? 54.385  79.195  10.150  1.00 43.04  ? 460  SER   A C     1 
ATOM   1856  O  O     . SER   C 3 167 ? 54.062  78.178  10.767  1.00 42.81  ? 460  SER   A O     1 
ATOM   1857  C  CB    . SER   C 3 167 ? 55.308  79.104  7.828   1.00 36.76  ? 460  SER   A CB    1 
ATOM   1858  O  OG    . SER   C 3 167 ? 55.751  77.769  8.010   1.00 36.19  ? 460  SER   A OG    1 
ATOM   1859  N  N     . LEU   C 3 168 ? 55.016  80.227  10.728  1.00 46.29  ? 461  LEU   A N     1 
ATOM   1860  C  CA    . LEU   C 3 168 ? 55.403  80.268  12.130  1.00 44.70  ? 461  LEU   A CA    1 
ATOM   1861  C  C     . LEU   C 3 168 ? 54.142  80.224  12.997  1.00 45.13  ? 461  LEU   A C     1 
ATOM   1862  O  O     . LEU   C 3 168 ? 54.019  79.445  13.947  1.00 45.29  ? 461  LEU   A O     1 
ATOM   1863  C  CB    . LEU   C 3 168 ? 56.225  81.555  12.293  1.00 51.30  ? 461  LEU   A CB    1 
ATOM   1864  C  CG    . LEU   C 3 168 ? 56.960  81.796  13.609  1.00 57.50  ? 461  LEU   A CG    1 
ATOM   1865  C  CD1   . LEU   C 3 168 ? 58.148  82.717  13.370  1.00 57.52  ? 461  LEU   A CD1   1 
ATOM   1866  C  CD2   . LEU   C 3 168 ? 56.040  82.412  14.659  1.00 62.07  ? 461  LEU   A CD2   1 
ATOM   1867  N  N     . GLU   C 3 169 ? 53.149  81.018  12.625  1.00 42.79  ? 462  GLU   A N     1 
ATOM   1868  C  CA    . GLU   C 3 169 ? 51.920  81.064  13.396  1.00 42.99  ? 462  GLU   A CA    1 
ATOM   1869  C  C     . GLU   C 3 169 ? 51.187  79.719  13.365  1.00 43.30  ? 462  GLU   A C     1 
ATOM   1870  O  O     . GLU   C 3 169 ? 50.630  79.289  14.375  1.00 44.97  ? 462  GLU   A O     1 
ATOM   1871  C  CB    . GLU   C 3 169 ? 51.068  82.205  12.856  1.00 45.45  ? 462  GLU   A CB    1 
ATOM   1872  C  CG    . GLU   C 3 169 ? 49.662  82.199  13.410  1.00 50.99  ? 462  GLU   A CG    1 
ATOM   1873  C  CD    . GLU   C 3 169 ? 48.843  83.370  12.906  1.00 52.71  ? 462  GLU   A CD    1 
ATOM   1874  O  OE1   . GLU   C 3 169 ? 49.433  84.236  12.206  1.00 52.39  ? 462  GLU   A OE1   1 
ATOM   1875  O  OE2   . GLU   C 3 169 ? 47.627  83.403  13.212  1.00 55.07  ? 462  GLU   A OE2   1 
ATOM   1876  N  N     . VAL   C 3 170 ? 51.181  79.057  12.201  1.00 41.34  ? 463  VAL   A N     1 
ATOM   1877  C  CA    . VAL   C 3 170 ? 50.475  77.793  12.025  1.00 40.15  ? 463  VAL   A CA    1 
ATOM   1878  C  C     . VAL   C 3 170 ? 51.223  76.658  12.731  1.00 37.02  ? 463  VAL   A C     1 
ATOM   1879  O  O     . VAL   C 3 170 ? 50.579  75.818  13.351  1.00 41.66  ? 463  VAL   A O     1 
ATOM   1880  C  CB    . VAL   C 3 170 ? 50.249  77.484  10.523  1.00 41.63  ? 463  VAL   A CB    1 
ATOM   1881  C  CG1   . VAL   C 3 170 ? 49.800  76.044  10.285  1.00 43.34  ? 463  VAL   A CG1   1 
ATOM   1882  C  CG2   . VAL   C 3 170 ? 49.263  78.458  9.892   1.00 41.91  ? 463  VAL   A CG2   1 
ATOM   1883  N  N     . ALA   C 3 171 ? 52.560  76.597  12.579  1.00 38.77  ? 464  ALA   A N     1 
ATOM   1884  C  CA    . ALA   C 3 171 ? 53.410  75.641  13.295  1.00 41.33  ? 464  ALA   A CA    1 
ATOM   1885  C  C     . ALA   C 3 171 ? 53.066  75.605  14.789  1.00 39.35  ? 464  ALA   A C     1 
ATOM   1886  O  O     . ALA   C 3 171 ? 52.871  74.522  15.355  1.00 42.62  ? 464  ALA   A O     1 
ATOM   1887  C  CB    . ALA   C 3 171 ? 54.872  75.976  13.081  1.00 40.99  ? 464  ALA   A CB    1 
ATOM   1888  N  N     . GLU   C 3 172 ? 52.945  76.796  15.401  1.00 37.80  ? 465  GLU   A N     1 
ATOM   1889  C  CA    . GLU   C 3 172 ? 52.635  76.927  16.822  1.00 41.22  ? 465  GLU   A CA    1 
ATOM   1890  C  C     . GLU   C 3 172 ? 51.264  76.327  17.133  1.00 42.65  ? 465  GLU   A C     1 
ATOM   1891  O  O     . GLU   C 3 172 ? 51.092  75.680  18.173  1.00 42.77  ? 465  GLU   A O     1 
ATOM   1892  C  CB    . GLU   C 3 172 ? 52.703  78.389  17.294  1.00 41.90  ? 465  GLU   A CB    1 
ATOM   1893  C  CG    . GLU   C 3 172 ? 52.560  78.543  18.814  1.00 43.08  ? 465  GLU   A CG    1 
ATOM   1894  C  CD    . GLU   C 3 172 ? 51.153  78.591  19.406  1.00 50.39  ? 465  GLU   A CD    1 
ATOM   1895  O  OE1   . GLU   C 3 172 ? 50.194  78.942  18.669  1.00 51.86  ? 465  GLU   A OE1   1 
ATOM   1896  O  OE2   . GLU   C 3 172 ? 51.005  78.279  20.613  1.00 50.56  ? 465  GLU   A OE2   1 
ATOM   1897  N  N     . GLU   C 3 173 ? 50.287  76.553  16.247  1.00 42.52  ? 466  GLU   A N     1 
ATOM   1898  C  CA    . GLU   C 3 173 ? 48.952  76.019  16.474  1.00 45.45  ? 466  GLU   A CA    1 
ATOM   1899  C  C     . GLU   C 3 173 ? 49.001  74.497  16.352  1.00 43.29  ? 466  GLU   A C     1 
ATOM   1900  O  O     . GLU   C 3 173 ? 48.366  73.782  17.130  1.00 41.25  ? 466  GLU   A O     1 
ATOM   1901  C  CB    . GLU   C 3 173 ? 47.935  76.633  15.506  1.00 53.67  ? 466  GLU   A CB    1 
ATOM   1902  C  CG    . GLU   C 3 173 ? 46.948  77.589  16.151  1.00 62.62  ? 466  GLU   A CG    1 
ATOM   1903  C  CD    . GLU   C 3 173 ? 45.659  76.949  16.660  1.00 72.80  ? 466  GLU   A CD    1 
ATOM   1904  O  OE1   . GLU   C 3 173 ? 44.635  77.070  15.954  1.00 72.34  ? 466  GLU   A OE1   1 
ATOM   1905  O  OE2   . GLU   C 3 173 ? 45.657  76.372  17.781  1.00 73.67  ? 466  GLU   A OE2   1 
ATOM   1906  N  N     . ILE   C 3 174 ? 49.763  74.000  15.371  1.00 42.31  ? 467  ILE   A N     1 
ATOM   1907  C  CA    . ILE   C 3 174 ? 49.847  72.565  15.142  1.00 44.77  ? 467  ILE   A CA    1 
ATOM   1908  C  C     . ILE   C 3 174 ? 50.409  71.880  16.393  1.00 47.91  ? 467  ILE   A C     1 
ATOM   1909  O  O     . ILE   C 3 174 ? 49.867  70.866  16.838  1.00 47.20  ? 467  ILE   A O     1 
ATOM   1910  C  CB    . ILE   C 3 174 ? 50.665  72.245  13.869  1.00 43.78  ? 467  ILE   A CB    1 
ATOM   1911  C  CG1   . ILE   C 3 174 ? 49.908  72.676  12.603  1.00 45.89  ? 467  ILE   A CG1   1 
ATOM   1912  C  CG2   . ILE   C 3 174 ? 51.029  70.761  13.832  1.00 42.22  ? 467  ILE   A CG2   1 
ATOM   1913  C  CD1   . ILE   C 3 174 ? 50.728  72.693  11.330  1.00 42.44  ? 467  ILE   A CD1   1 
ATOM   1914  N  N     . ALA   C 3 175 ? 51.497  72.435  16.955  1.00 52.71  ? 468  ALA   A N     1 
ATOM   1915  C  CA    . ALA   C 3 175 ? 52.106  71.866  18.156  1.00 53.00  ? 468  ALA   A CA    1 
ATOM   1916  C  C     . ALA   C 3 175 ? 51.084  71.822  19.292  1.00 48.84  ? 468  ALA   A C     1 
ATOM   1917  O  O     . ALA   C 3 175 ? 50.935  70.806  19.969  1.00 52.41  ? 468  ALA   A O     1 
ATOM   1918  C  CB    . ALA   C 3 175 ? 53.340  72.646  18.542  1.00 51.55  ? 468  ALA   A CB    1 
ATOM   1919  N  N     . ARG   C 3 176 ? 50.333  72.913  19.457  1.00 51.06  ? 469  ARG   A N     1 
ATOM   1920  C  CA    . ARG   C 3 176 ? 49.400  73.022  20.564  1.00 53.65  ? 469  ARG   A CA    1 
ATOM   1921  C  C     . ARG   C 3 176 ? 48.301  71.976  20.416  1.00 53.97  ? 469  ARG   A C     1 
ATOM   1922  O  O     . ARG   C 3 176 ? 47.941  71.345  21.402  1.00 55.79  ? 469  ARG   A O     1 
ATOM   1923  C  CB    . ARG   C 3 176 ? 48.850  74.450  20.665  1.00 55.19  ? 469  ARG   A CB    1 
ATOM   1924  C  CG    . ARG   C 3 176 ? 47.795  74.639  21.748  1.00 58.89  ? 469  ARG   A CG    1 
ATOM   1925  C  CD    . ARG   C 3 176 ? 47.847  75.994  22.436  1.00 61.54  ? 469  ARG   A CD    1 
ATOM   1926  N  NE    . ARG   C 3 176 ? 48.051  77.087  21.505  1.00 64.80  ? 469  ARG   A NE    1 
ATOM   1927  C  CZ    . ARG   C 3 176 ? 47.221  77.387  20.509  1.00 74.72  ? 469  ARG   A CZ    1 
ATOM   1928  N  NH1   . ARG   C 3 176 ? 47.581  78.269  19.594  1.00 66.71  ? 469  ARG   A NH1   1 
ATOM   1929  N  NH2   . ARG   C 3 176 ? 46.044  76.790  20.416  1.00 77.43  ? 469  ARG   A NH2   1 
ATOM   1930  N  N     . LEU   C 3 177 ? 47.789  71.791  19.186  1.00 60.59  ? 470  LEU   A N     1 
ATOM   1931  C  CA    . LEU   C 3 177 ? 46.703  70.855  18.915  1.00 54.18  ? 470  LEU   A CA    1 
ATOM   1932  C  C     . LEU   C 3 177 ? 47.196  69.418  19.084  1.00 53.78  ? 470  LEU   A C     1 
ATOM   1933  O  O     . LEU   C 3 177 ? 46.462  68.555  19.573  1.00 57.92  ? 470  LEU   A O     1 
ATOM   1934  C  CB    . LEU   C 3 177 ? 46.168  71.071  17.491  1.00 55.15  ? 470  LEU   A CB    1 
ATOM   1935  C  CG    . LEU   C 3 177 ? 45.417  72.379  17.220  1.00 56.78  ? 470  LEU   A CG    1 
ATOM   1936  C  CD1   . LEU   C 3 177 ? 45.271  72.600  15.723  1.00 56.25  ? 470  LEU   A CD1   1 
ATOM   1937  C  CD2   . LEU   C 3 177 ? 44.040  72.390  17.876  1.00 54.48  ? 470  LEU   A CD2   1 
ATOM   1938  N  N     . GLU   C 3 178 ? 48.429  69.144  18.647  1.00 48.20  ? 471  GLU   A N     1 
ATOM   1939  C  CA    . GLU   C 3 178 ? 48.978  67.806  18.817  1.00 54.20  ? 471  GLU   A CA    1 
ATOM   1940  C  C     . GLU   C 3 178 ? 48.994  67.416  20.298  1.00 53.33  ? 471  GLU   A C     1 
ATOM   1941  O  O     . GLU   C 3 178 ? 48.556  66.321  20.644  1.00 50.90  ? 471  GLU   A O     1 
ATOM   1942  C  CB    . GLU   C 3 178 ? 50.391  67.701  18.243  1.00 52.41  ? 471  GLU   A CB    1 
ATOM   1943  C  CG    . GLU   C 3 178 ? 50.912  66.282  18.268  1.00 51.93  ? 471  GLU   A CG    1 
ATOM   1944  C  CD    . GLU   C 3 178 ? 52.333  66.152  17.773  1.00 53.47  ? 471  GLU   A CD    1 
ATOM   1945  O  OE1   . GLU   C 3 178 ? 53.247  66.656  18.468  1.00 47.78  ? 471  GLU   A OE1   1 
ATOM   1946  O  OE2   . GLU   C 3 178 ? 52.509  65.560  16.694  1.00 57.83  ? 471  GLU   A OE2   1 
ATOM   1947  N  N     . ALA   C 3 179 ? 49.510  68.317  21.150  1.00 53.44  ? 472  ALA   A N     1 
ATOM   1948  C  CA    . ALA   C 3 179 ? 49.606  68.097  22.589  1.00 59.08  ? 472  ALA   A CA    1 
ATOM   1949  C  C     . ALA   C 3 179 ? 48.221  67.851  23.177  1.00 62.21  ? 472  ALA   A C     1 
ATOM   1950  O  O     . ALA   C 3 179 ? 48.020  66.894  23.930  1.00 64.07  ? 472  ALA   A O     1 
ATOM   1951  C  CB    . ALA   C 3 179 ? 50.272  69.278  23.260  1.00 55.12  ? 472  ALA   A CB    1 
ATOM   1952  N  N     . GLU   C 3 180 ? 47.266  68.711  22.800  1.00 70.23  ? 473  GLU   A N     1 
ATOM   1953  C  CA    . GLU   C 3 180 ? 45.906  68.635  23.314  1.00 73.09  ? 473  GLU   A CA    1 
ATOM   1954  C  C     . GLU   C 3 180 ? 45.232  67.331  22.864  1.00 69.29  ? 473  GLU   A C     1 
ATOM   1955  O  O     . GLU   C 3 180 ? 44.342  66.844  23.556  1.00 77.83  ? 473  GLU   A O     1 
ATOM   1956  C  CB    . GLU   C 3 180 ? 45.138  69.910  22.936  1.00 79.78  ? 473  GLU   A CB    1 
ATOM   1957  C  CG    . GLU   C 3 180 ? 45.661  71.170  23.641  1.00 85.30  ? 473  GLU   A CG    1 
ATOM   1958  C  CD    . GLU   C 3 180 ? 45.116  72.526  23.184  1.00 96.56  ? 473  GLU   A CD    1 
ATOM   1959  O  OE1   . GLU   C 3 180 ? 44.399  72.583  22.150  1.00 94.81  ? 473  GLU   A OE1   1 
ATOM   1960  O  OE2   . GLU   C 3 180 ? 45.409  73.549  23.868  1.00 92.73  ? 473  GLU   A OE2   1 
ATOM   1961  N  N     . VAL   C 3 181 ? 45.665  66.736  21.738  1.00 68.81  ? 474  VAL   A N     1 
ATOM   1962  C  CA    . VAL   C 3 181 ? 45.093  65.475  21.266  1.00 66.47  ? 474  VAL   A CA    1 
ATOM   1963  C  C     . VAL   C 3 181 ? 45.804  64.279  21.914  1.00 63.49  ? 474  VAL   A C     1 
ATOM   1964  O  O     . VAL   C 3 181 ? 45.177  63.239  22.116  1.00 56.79  ? 474  VAL   A O     1 
ATOM   1965  C  CB    . VAL   C 3 181 ? 45.109  65.362  19.724  1.00 65.63  ? 474  VAL   A CB    1 
ATOM   1966  C  CG1   . VAL   C 3 181 ? 44.681  63.982  19.234  1.00 62.72  ? 474  VAL   A CG1   1 
ATOM   1967  C  CG2   . VAL   C 3 181 ? 44.252  66.431  19.063  1.00 65.59  ? 474  VAL   A CG2   1 
ATOM   1968  N  N     . PHE   C 3 182 ? 47.116  64.396  22.181  1.00 63.71  ? 475  PHE   A N     1 
ATOM   1969  C  CA    . PHE   C 3 182 ? 47.847  63.390  22.949  1.00 62.75  ? 475  PHE   A CA    1 
ATOM   1970  C  C     . PHE   C 3 182 ? 47.228  63.246  24.341  1.00 64.08  ? 475  PHE   A C     1 
ATOM   1971  O  O     . PHE   C 3 182 ? 46.901  62.144  24.776  1.00 61.61  ? 475  PHE   A O     1 
ATOM   1972  C  CB    . PHE   C 3 182 ? 49.332  63.754  23.084  1.00 54.03  ? 475  PHE   A CB    1 
ATOM   1973  C  CG    . PHE   C 3 182 ? 50.180  63.572  21.850  1.00 50.76  ? 475  PHE   A CG    1 
ATOM   1974  C  CD1   . PHE   C 3 182 ? 49.630  63.155  20.645  1.00 48.31  ? 475  PHE   A CD1   1 
ATOM   1975  C  CD2   . PHE   C 3 182 ? 51.542  63.834  21.894  1.00 47.65  ? 475  PHE   A CD2   1 
ATOM   1976  C  CE1   . PHE   C 3 182 ? 50.422  62.987  19.521  1.00 46.58  ? 475  PHE   A CE1   1 
ATOM   1977  C  CE2   . PHE   C 3 182 ? 52.329  63.680  20.761  1.00 45.32  ? 475  PHE   A CE2   1 
ATOM   1978  C  CZ    . PHE   C 3 182 ? 51.768  63.248  19.580  1.00 45.28  ? 475  PHE   A CZ    1 
ATOM   1979  N  N     . ARG   C 3 183 ? 47.074  64.381  25.028  1.00 69.84  ? 476  ARG   A N     1 
ATOM   1980  C  CA    . ARG   C 3 183 ? 46.463  64.408  26.345  1.00 77.21  ? 476  ARG   A CA    1 
ATOM   1981  C  C     . ARG   C 3 183 ? 45.115  63.681  26.292  1.00 71.90  ? 476  ARG   A C     1 
ATOM   1982  O  O     . ARG   C 3 183 ? 44.866  62.787  27.093  1.00 76.91  ? 476  ARG   A O     1 
ATOM   1983  C  CB    . ARG   C 3 183 ? 46.353  65.860  26.832  1.00 80.22  ? 476  ARG   A CB    1 
ATOM   1984  C  CG    . ARG   C 3 183 ? 46.368  66.007  28.347  1.00 85.37  ? 476  ARG   A CG    1 
ATOM   1985  C  CD    . ARG   C 3 183 ? 45.906  67.374  28.825  1.00 85.69  ? 476  ARG   A CD    1 
ATOM   1986  N  NE    . ARG   C 3 183 ? 44.539  67.694  28.411  1.00 93.46  ? 476  ARG   A NE    1 
ATOM   1987  C  CZ    . ARG   C 3 183 ? 43.444  67.006  28.744  1.00 87.37  ? 476  ARG   A CZ    1 
ATOM   1988  N  NH1   . ARG   C 3 183 ? 43.478  66.122  29.725  1.00 91.75  ? 476  ARG   A NH1   1 
ATOM   1989  N  NH2   . ARG   C 3 183 ? 42.309  67.212  28.096  1.00 78.70  ? 476  ARG   A NH2   1 
ATOM   1990  N  N     . LEU   C 3 184 ? 44.277  64.011  25.302  1.00 73.02  ? 477  LEU   A N     1 
ATOM   1991  C  CA    . LEU   C 3 184 ? 42.896  63.542  25.249  1.00 71.81  ? 477  LEU   A CA    1 
ATOM   1992  C  C     . LEU   C 3 184 ? 42.798  62.049  24.930  1.00 74.33  ? 477  LEU   A C     1 
ATOM   1993  O  O     . LEU   C 3 184 ? 41.752  61.456  25.173  1.00 81.86  ? 477  LEU   A O     1 
ATOM   1994  C  CB    . LEU   C 3 184 ? 42.111  64.364  24.215  1.00 74.88  ? 477  LEU   A CB    1 
ATOM   1995  C  CG    . LEU   C 3 184 ? 41.328  65.558  24.768  1.00 78.13  ? 477  LEU   A CG    1 
ATOM   1996  C  CD1   . LEU   C 3 184 ? 40.945  66.529  23.662  1.00 74.75  ? 477  LEU   A CD1   1 
ATOM   1997  C  CD2   . LEU   C 3 184 ? 40.074  65.094  25.508  1.00 79.62  ? 477  LEU   A CD2   1 
ATOM   1998  N  N     . ALA   C 3 185 ? 43.855  61.443  24.372  1.00 73.74  ? 478  ALA   A N     1 
ATOM   1999  C  CA    . ALA   C 3 185 ? 43.799  60.055  23.937  1.00 74.05  ? 478  ALA   A CA    1 
ATOM   2000  C  C     . ALA   C 3 185 ? 44.512  59.122  24.918  1.00 76.24  ? 478  ALA   A C     1 
ATOM   2001  O  O     . ALA   C 3 185 ? 44.318  57.910  24.860  1.00 76.21  ? 478  ALA   A O     1 
ATOM   2002  C  CB    . ALA   C 3 185 ? 44.400  59.932  22.559  1.00 77.30  ? 478  ALA   A CB    1 
ATOM   2003  N  N     . GLY   C 3 186 ? 45.361  59.683  25.787  1.00 75.96  ? 479  GLY   A N     1 
ATOM   2004  C  CA    . GLY   C 3 186 ? 46.136  58.895  26.730  1.00 76.72  ? 479  GLY   A CA    1 
ATOM   2005  C  C     . GLY   C 3 186 ? 47.619  58.849  26.368  1.00 77.88  ? 479  GLY   A C     1 
ATOM   2006  O  O     . GLY   C 3 186 ? 48.472  58.807  27.248  1.00 86.13  ? 479  GLY   A O     1 
ATOM   2007  N  N     . HIS   C 3 187 ? 47.917  58.886  25.067  1.00 75.17  ? 480  HIS   A N     1 
ATOM   2008  C  CA    . HIS   C 3 187 ? 49.231  58.521  24.570  1.00 69.83  ? 480  HIS   A CA    1 
ATOM   2009  C  C     . HIS   C 3 187 ? 49.533  59.275  23.279  1.00 67.65  ? 480  HIS   A C     1 
ATOM   2010  O  O     . HIS   C 3 187 ? 48.606  59.650  22.566  1.00 61.61  ? 480  HIS   A O     1 
ATOM   2011  C  CB    . HIS   C 3 187 ? 49.273  57.008  24.314  1.00 74.12  ? 480  HIS   A CB    1 
ATOM   2012  C  CG    . HIS   C 3 187 ? 48.216  56.492  23.377  1.00 72.47  ? 480  HIS   A CG    1 
ATOM   2013  N  ND1   . HIS   C 3 187 ? 48.448  56.178  22.054  1.00 70.32  ? 480  HIS   A ND1   1 
ATOM   2014  C  CD2   . HIS   C 3 187 ? 46.890  56.267  23.608  1.00 66.91  ? 480  HIS   A CD2   1 
ATOM   2015  C  CE1   . HIS   C 3 187 ? 47.316  55.752  21.496  1.00 66.72  ? 480  HIS   A CE1   1 
ATOM   2016  N  NE2   . HIS   C 3 187 ? 46.339  55.799  22.444  1.00 69.34  ? 480  HIS   A NE2   1 
ATOM   2017  N  N     . PRO   C 3 188 ? 50.825  59.521  22.942  1.00 68.31  ? 481  PRO   A N     1 
ATOM   2018  C  CA    . PRO   C 3 188 ? 51.222  59.897  21.581  1.00 60.39  ? 481  PRO   A CA    1 
ATOM   2019  C  C     . PRO   C 3 188 ? 50.791  58.927  20.479  1.00 52.85  ? 481  PRO   A C     1 
ATOM   2020  O  O     . PRO   C 3 188 ? 50.513  57.758  20.742  1.00 55.14  ? 481  PRO   A O     1 
ATOM   2021  C  CB    . PRO   C 3 188 ? 52.767  59.944  21.620  1.00 65.06  ? 481  PRO   A CB    1 
ATOM   2022  C  CG    . PRO   C 3 188 ? 53.155  59.311  22.943  1.00 72.55  ? 481  PRO   A CG    1 
ATOM   2023  C  CD    . PRO   C 3 188 ? 51.973  59.554  23.863  1.00 71.12  ? 481  PRO   A CD    1 
ATOM   2024  N  N     . PHE   C 3 189 ? 50.724  59.459  19.248  1.00 46.85  ? 482  PHE   A N     1 
ATOM   2025  C  CA    . PHE   C 3 189 ? 50.525  58.698  18.021  1.00 45.15  ? 482  PHE   A CA    1 
ATOM   2026  C  C     . PHE   C 3 189 ? 50.673  59.652  16.836  1.00 42.13  ? 482  PHE   A C     1 
ATOM   2027  O  O     . PHE   C 3 189 ? 50.824  60.861  17.030  1.00 41.32  ? 482  PHE   A O     1 
ATOM   2028  C  CB    . PHE   C 3 189 ? 49.171  57.972  17.992  1.00 47.72  ? 482  PHE   A CB    1 
ATOM   2029  C  CG    . PHE   C 3 189 ? 47.955  58.867  17.960  1.00 53.26  ? 482  PHE   A CG    1 
ATOM   2030  C  CD1   . PHE   C 3 189 ? 47.537  59.550  19.096  1.00 53.03  ? 482  PHE   A CD1   1 
ATOM   2031  C  CD2   . PHE   C 3 189 ? 47.241  59.044  16.782  1.00 54.38  ? 482  PHE   A CD2   1 
ATOM   2032  C  CE1   . PHE   C 3 189 ? 46.426  60.379  19.059  1.00 54.84  ? 482  PHE   A CE1   1 
ATOM   2033  C  CE2   . PHE   C 3 189 ? 46.128  59.869  16.750  1.00 53.09  ? 482  PHE   A CE2   1 
ATOM   2034  C  CZ    . PHE   C 3 189 ? 45.727  60.538  17.885  1.00 55.21  ? 482  PHE   A CZ    1 
ATOM   2035  N  N     . ASN   C 3 190 ? 50.659  59.101  15.614  1.00 39.63  ? 483  ASN   A N     1 
ATOM   2036  C  CA    . ASN   C 3 190 ? 50.724  59.926  14.417  1.00 41.33  ? 483  ASN   A CA    1 
ATOM   2037  C  C     . ASN   C 3 190 ? 49.311  60.372  14.016  1.00 43.83  ? 483  ASN   A C     1 
ATOM   2038  O  O     . ASN   C 3 190 ? 48.515  59.555  13.542  1.00 42.52  ? 483  ASN   A O     1 
ATOM   2039  C  CB    . ASN   C 3 190 ? 51.435  59.178  13.290  1.00 40.25  ? 483  ASN   A CB    1 
ATOM   2040  C  CG    . ASN   C 3 190 ? 51.811  60.099  12.160  1.00 39.06  ? 483  ASN   A CG    1 
ATOM   2041  O  OD1   . ASN   C 3 190 ? 51.389  61.251  12.155  1.00 39.22  ? 483  ASN   A OD1   1 
ATOM   2042  N  ND2   . ASN   C 3 190 ? 52.597  59.601  11.220  1.00 34.95  ? 483  ASN   A ND2   1 
ATOM   2043  N  N     . LEU   C 3 191 ? 48.995  61.668  14.222  1.00 43.31  ? 484  LEU   A N     1 
ATOM   2044  C  CA    . LEU   C 3 191 ? 47.699  62.230  13.846  1.00 43.91  ? 484  LEU   A CA    1 
ATOM   2045  C  C     . LEU   C 3 191 ? 47.501  62.195  12.324  1.00 41.19  ? 484  LEU   A C     1 
ATOM   2046  O  O     . LEU   C 3 191 ? 46.369  62.116  11.875  1.00 47.09  ? 484  LEU   A O     1 
ATOM   2047  C  CB    . LEU   C 3 191 ? 47.548  63.661  14.384  1.00 44.93  ? 484  LEU   A CB    1 
ATOM   2048  C  CG    . LEU   C 3 191 ? 47.112  63.795  15.850  1.00 46.84  ? 484  LEU   A CG    1 
ATOM   2049  C  CD1   . LEU   C 3 191 ? 48.215  63.343  16.794  1.00 49.43  ? 484  LEU   A CD1   1 
ATOM   2050  C  CD2   . LEU   C 3 191 ? 46.718  65.228  16.195  1.00 44.03  ? 484  LEU   A CD2   1 
ATOM   2051  N  N     . ASN   C 3 192 ? 48.597  62.199  11.554  1.00 43.66  ? 485  ASN   A N     1 
ATOM   2052  C  CA    . ASN   C 3 192 ? 48.584  62.114  10.099  1.00 45.64  ? 485  ASN   A CA    1 
ATOM   2053  C  C     . ASN   C 3 192 ? 48.398  60.687  9.574   1.00 45.91  ? 485  ASN   A C     1 
ATOM   2054  O  O     . ASN   C 3 192 ? 48.375  60.497  8.361   1.00 44.54  ? 485  ASN   A O     1 
ATOM   2055  C  CB    . ASN   C 3 192 ? 49.911  62.585  9.494   1.00 45.54  ? 485  ASN   A CB    1 
ATOM   2056  C  CG    . ASN   C 3 192 ? 50.228  64.036  9.758   1.00 51.89  ? 485  ASN   A CG    1 
ATOM   2057  O  OD1   . ASN   C 3 192 ? 49.375  64.902  9.566   1.00 57.50  ? 485  ASN   A OD1   1 
ATOM   2058  N  ND2   . ASN   C 3 192 ? 51.457  64.304  10.173  1.00 57.95  ? 485  ASN   A ND2   1 
ATOM   2059  N  N     . SER   C 3 193 ? 48.364  59.682  10.459  1.00 45.97  ? 486  SER   A N     1 
ATOM   2060  C  CA    . SER   C 3 193 ? 48.136  58.302  10.049  1.00 52.37  ? 486  SER   A CA    1 
ATOM   2061  C  C     . SER   C 3 193 ? 46.653  57.966  10.215  1.00 53.30  ? 486  SER   A C     1 
ATOM   2062  O  O     . SER   C 3 193 ? 46.146  57.908  11.339  1.00 49.50  ? 486  SER   A O     1 
ATOM   2063  C  CB    . SER   C 3 193 ? 49.010  57.339  10.823  1.00 54.58  ? 486  SER   A CB    1 
ATOM   2064  O  OG    . SER   C 3 193 ? 48.552  55.992  10.697  1.00 55.81  ? 486  SER   A OG    1 
ATOM   2065  N  N     . ARG   C 3 194 ? 45.955  57.759  9.087   1.00 53.39  ? 487  ARG   A N     1 
ATOM   2066  C  CA    . ARG   C 3 194 ? 44.553  57.364  9.146   1.00 51.62  ? 487  ARG   A CA    1 
ATOM   2067  C  C     . ARG   C 3 194 ? 44.439  55.991  9.821   1.00 52.00  ? 487  ARG   A C     1 
ATOM   2068  O  O     . ARG   C 3 194 ? 43.510  55.774  10.588  1.00 49.75  ? 487  ARG   A O     1 
ATOM   2069  C  CB    . ARG   C 3 194 ? 43.886  57.461  7.768   1.00 46.60  ? 487  ARG   A CB    1 
ATOM   2070  C  CG    . ARG   C 3 194 ? 44.484  56.592  6.665   1.00 47.50  ? 487  ARG   A CG    1 
ATOM   2071  C  CD    . ARG   C 3 194 ? 43.916  55.181  6.586   1.00 47.18  ? 487  ARG   A CD    1 
ATOM   2072  N  NE    . ARG   C 3 194 ? 42.461  55.147  6.698   1.00 49.13  ? 487  ARG   A NE    1 
ATOM   2073  C  CZ    . ARG   C 3 194 ? 41.778  54.331  7.490   1.00 53.17  ? 487  ARG   A CZ    1 
ATOM   2074  N  NH1   . ARG   C 3 194 ? 42.312  53.178  7.865   1.00 54.91  ? 487  ARG   A NH1   1 
ATOM   2075  N  NH2   . ARG   C 3 194 ? 40.563  54.673  7.891   1.00 51.26  ? 487  ARG   A NH2   1 
ATOM   2076  N  N     . ASP   C 3 195 ? 45.407  55.083  9.608   1.00 52.56  ? 488  ASP   A N     1 
ATOM   2077  C  CA    . ASP   C 3 195 ? 45.358  53.777  10.262  1.00 54.12  ? 488  ASP   A CA    1 
ATOM   2078  C  C     . ASP   C 3 195 ? 45.347  53.938  11.784  1.00 52.48  ? 488  ASP   A C     1 
ATOM   2079  O  O     . ASP   C 3 195 ? 44.526  53.309  12.442  1.00 52.87  ? 488  ASP   A O     1 
ATOM   2080  C  CB    . ASP   C 3 195 ? 46.497  52.850  9.827   1.00 52.87  ? 488  ASP   A CB    1 
ATOM   2081  C  CG    . ASP   C 3 195 ? 46.311  52.190  8.472   1.00 56.39  ? 488  ASP   A CG    1 
ATOM   2082  O  OD1   . ASP   C 3 195 ? 45.148  52.079  8.015   1.00 58.60  ? 488  ASP   A OD1   1 
ATOM   2083  O  OD2   . ASP   C 3 195 ? 47.338  51.806  7.872   1.00 60.36  ? 488  ASP   A OD2   1 
ATOM   2084  N  N     . GLN   C 3 196 ? 46.236  54.782  12.340  1.00 58.18  ? 489  GLN   A N     1 
ATOM   2085  C  CA    . GLN   C 3 196 ? 46.379  54.921  13.789  1.00 55.90  ? 489  GLN   A CA    1 
ATOM   2086  C  C     . GLN   C 3 196 ? 45.210  55.719  14.373  1.00 59.81  ? 489  GLN   A C     1 
ATOM   2087  O  O     . GLN   C 3 196 ? 44.841  55.507  15.532  1.00 59.72  ? 489  GLN   A O     1 
ATOM   2088  C  CB    . GLN   C 3 196 ? 47.707  55.587  14.173  1.00 57.00  ? 489  GLN   A CB    1 
ATOM   2089  C  CG    . GLN   C 3 196 ? 48.957  54.803  13.768  1.00 58.16  ? 489  GLN   A CG    1 
ATOM   2090  C  CD    . GLN   C 3 196 ? 50.240  55.550  14.062  1.00 58.40  ? 489  GLN   A CD    1 
ATOM   2091  O  OE1   . GLN   C 3 196 ? 50.420  56.088  15.156  1.00 61.29  ? 489  GLN   A OE1   1 
ATOM   2092  N  NE2   . GLN   C 3 196 ? 51.136  55.609  13.081  1.00 48.02  ? 489  GLN   A NE2   1 
ATOM   2093  N  N     . LEU   C 3 197 ? 44.656  56.654  13.579  1.00 64.03  ? 490  LEU   A N     1 
ATOM   2094  C  CA    . LEU   C 3 197 ? 43.487  57.437  13.976  1.00 60.77  ? 490  LEU   A CA    1 
ATOM   2095  C  C     . LEU   C 3 197 ? 42.243  56.556  14.095  1.00 59.07  ? 490  LEU   A C     1 
ATOM   2096  O  O     . LEU   C 3 197 ? 41.370  56.842  14.921  1.00 53.20  ? 490  LEU   A O     1 
ATOM   2097  C  CB    . LEU   C 3 197 ? 43.219  58.524  12.931  1.00 60.39  ? 490  LEU   A CB    1 
ATOM   2098  C  CG    . LEU   C 3 197 ? 43.428  59.966  13.368  1.00 62.47  ? 490  LEU   A CG    1 
ATOM   2099  C  CD1   . LEU   C 3 197 ? 42.922  60.908  12.279  1.00 65.12  ? 490  LEU   A CD1   1 
ATOM   2100  C  CD2   . LEU   C 3 197 ? 42.748  60.245  14.702  1.00 59.69  ? 490  LEU   A CD2   1 
ATOM   2101  N  N     . GLU   C 3 198 ? 42.141  55.564  13.187  1.00 59.59  ? 491  GLU   A N     1 
ATOM   2102  C  CA    . GLU   C 3 198 ? 41.048  54.599  13.152  1.00 63.84  ? 491  GLU   A CA    1 
ATOM   2103  C  C     . GLU   C 3 198 ? 41.005  53.834  14.476  1.00 67.05  ? 491  GLU   A C     1 
ATOM   2104  O  O     . GLU   C 3 198 ? 39.976  53.838  15.154  1.00 59.60  ? 491  GLU   A O     1 
ATOM   2105  C  CB    . GLU   C 3 198 ? 41.236  53.644  11.964  1.00 63.60  ? 491  GLU   A CB    1 
ATOM   2106  C  CG    . GLU   C 3 198 ? 40.140  52.593  11.807  1.00 60.24  ? 491  GLU   A CG    1 
ATOM   2107  C  CD    . GLU   C 3 198 ? 40.390  51.569  10.709  1.00 60.60  ? 491  GLU   A CD    1 
ATOM   2108  O  OE1   . GLU   C 3 198 ? 41.381  51.706  9.967   1.00 53.67  ? 491  GLU   A OE1   1 
ATOM   2109  O  OE2   . GLU   C 3 198 ? 39.594  50.621  10.600  1.00 71.38  ? 491  GLU   A OE2   1 
ATOM   2110  N  N     . ARG   C 3 199 ? 42.149  53.213  14.823  1.00 69.82  ? 492  ARG   A N     1 
ATOM   2111  C  CA    . ARG   C 3 199 ? 42.329  52.428  16.039  1.00 71.39  ? 492  ARG   A CA    1 
ATOM   2112  C  C     . ARG   C 3 199 ? 42.067  53.268  17.283  1.00 64.99  ? 492  ARG   A C     1 
ATOM   2113  O  O     . ARG   C 3 199 ? 41.492  52.770  18.240  1.00 76.63  ? 492  ARG   A O     1 
ATOM   2114  C  CB    . ARG   C 3 199 ? 43.747  51.851  16.110  1.00 74.27  ? 492  ARG   A CB    1 
ATOM   2115  C  CG    . ARG   C 3 199 ? 43.999  50.713  15.131  1.00 81.23  ? 492  ARG   A CG    1 
ATOM   2116  C  CD    . ARG   C 3 199 ? 45.456  50.640  14.719  1.00 87.37  ? 492  ARG   A CD    1 
ATOM   2117  N  NE    . ARG   C 3 199 ? 45.759  49.430  13.965  1.00 94.06  ? 492  ARG   A NE    1 
ATOM   2118  C  CZ    . ARG   C 3 199 ? 46.806  49.284  13.152  1.00 105.68 ? 492  ARG   A CZ    1 
ATOM   2119  N  NH1   . ARG   C 3 199 ? 47.270  50.318  12.466  1.00 96.77  ? 492  ARG   A NH1   1 
ATOM   2120  N  NH2   . ARG   C 3 199 ? 47.361  48.089  12.997  1.00 110.70 ? 492  ARG   A NH2   1 
ATOM   2121  N  N     . VAL   C 3 200 ? 42.478  54.535  17.272  1.00 62.22  ? 493  VAL   A N     1 
ATOM   2122  C  CA    . VAL   C 3 200 ? 42.343  55.381  18.447  1.00 62.69  ? 493  VAL   A CA    1 
ATOM   2123  C  C     . VAL   C 3 200 ? 40.891  55.824  18.626  1.00 64.53  ? 493  VAL   A C     1 
ATOM   2124  O  O     . VAL   C 3 200 ? 40.388  55.826  19.749  1.00 68.26  ? 493  VAL   A O     1 
ATOM   2125  C  CB    . VAL   C 3 200 ? 43.303  56.582  18.365  1.00 62.30  ? 493  VAL   A CB    1 
ATOM   2126  C  CG1   . VAL   C 3 200 ? 42.965  57.674  19.374  1.00 61.91  ? 493  VAL   A CG1   1 
ATOM   2127  C  CG2   . VAL   C 3 200 ? 44.748  56.131  18.511  1.00 61.84  ? 493  VAL   A CG2   1 
ATOM   2128  N  N     . LEU   C 3 201 ? 40.231  56.217  17.529  1.00 71.74  ? 494  LEU   A N     1 
ATOM   2129  C  CA    . LEU   C 3 201 ? 38.911  56.834  17.600  1.00 74.20  ? 494  LEU   A CA    1 
ATOM   2130  C  C     . LEU   C 3 201 ? 37.822  55.785  17.837  1.00 73.32  ? 494  LEU   A C     1 
ATOM   2131  O  O     . LEU   C 3 201 ? 36.854  56.041  18.551  1.00 65.65  ? 494  LEU   A O     1 
ATOM   2132  C  CB    . LEU   C 3 201 ? 38.638  57.609  16.303  1.00 77.05  ? 494  LEU   A CB    1 
ATOM   2133  C  CG    . LEU   C 3 201 ? 39.327  58.969  16.169  1.00 78.67  ? 494  LEU   A CG    1 
ATOM   2134  C  CD1   . LEU   C 3 201 ? 39.127  59.539  14.771  1.00 78.83  ? 494  LEU   A CD1   1 
ATOM   2135  C  CD2   . LEU   C 3 201 ? 38.815  59.958  17.213  1.00 75.69  ? 494  LEU   A CD2   1 
ATOM   2136  N  N     . PHE   C 3 202 ? 37.981  54.608  17.224  1.00 74.34  ? 495  PHE   A N     1 
ATOM   2137  C  CA    . PHE   C 3 202 ? 36.898  53.642  17.137  1.00 76.88  ? 495  PHE   A CA    1 
ATOM   2138  C  C     . PHE   C 3 202 ? 37.116  52.456  18.080  1.00 81.93  ? 495  PHE   A C     1 
ATOM   2139  O  O     . PHE   C 3 202 ? 36.139  51.911  18.590  1.00 81.40  ? 495  PHE   A O     1 
ATOM   2140  C  CB    . PHE   C 3 202 ? 36.728  53.187  15.686  1.00 75.66  ? 495  PHE   A CB    1 
ATOM   2141  C  CG    . PHE   C 3 202 ? 36.442  54.294  14.700  1.00 75.38  ? 495  PHE   A CG    1 
ATOM   2142  C  CD1   . PHE   C 3 202 ? 35.615  55.359  15.035  1.00 75.12  ? 495  PHE   A CD1   1 
ATOM   2143  C  CD2   . PHE   C 3 202 ? 36.975  54.256  13.419  1.00 74.74  ? 495  PHE   A CD2   1 
ATOM   2144  C  CE1   . PHE   C 3 202 ? 35.349  56.368  14.120  1.00 75.55  ? 495  PHE   A CE1   1 
ATOM   2145  C  CE2   . PHE   C 3 202 ? 36.702  55.261  12.504  1.00 72.96  ? 495  PHE   A CE2   1 
ATOM   2146  C  CZ    . PHE   C 3 202 ? 35.890  56.316  12.856  1.00 73.94  ? 495  PHE   A CZ    1 
ATOM   2147  N  N     . ASP   C 3 203 ? 38.380  52.050  18.289  1.00 82.57  ? 496  ASP   A N     1 
ATOM   2148  C  CA    . ASP   C 3 203 ? 38.705  50.970  19.211  1.00 78.94  ? 496  ASP   A CA    1 
ATOM   2149  C  C     . ASP   C 3 203 ? 38.838  51.527  20.631  1.00 80.33  ? 496  ASP   A C     1 
ATOM   2150  O  O     . ASP   C 3 203 ? 38.008  51.225  21.481  1.00 90.11  ? 496  ASP   A O     1 
ATOM   2151  C  CB    . ASP   C 3 203 ? 39.950  50.197  18.765  1.00 74.79  ? 496  ASP   A CB    1 
ATOM   2152  C  CG    . ASP   C 3 203 ? 39.799  49.467  17.440  1.00 75.51  ? 496  ASP   A CG    1 
ATOM   2153  O  OD1   . ASP   C 3 203 ? 38.651  49.303  16.986  1.00 76.85  ? 496  ASP   A OD1   1 
ATOM   2154  O  OD2   . ASP   C 3 203 ? 40.838  49.073  16.862  1.00 74.34  ? 496  ASP   A OD2   1 
ATOM   2155  N  N     . GLU   C 3 204 ? 39.859  52.360  20.880  1.00 79.46  ? 497  GLU   A N     1 
ATOM   2156  C  CA    . GLU   C 3 204 ? 40.201  52.787  22.233  1.00 75.41  ? 497  GLU   A CA    1 
ATOM   2157  C  C     . GLU   C 3 204 ? 39.109  53.686  22.818  1.00 77.22  ? 497  GLU   A C     1 
ATOM   2158  O  O     . GLU   C 3 204 ? 38.647  53.459  23.939  1.00 77.98  ? 497  GLU   A O     1 
ATOM   2159  C  CB    . GLU   C 3 204 ? 41.533  53.542  22.266  1.00 69.56  ? 497  GLU   A CB    1 
ATOM   2160  C  CG    . GLU   C 3 204 ? 42.734  52.732  21.799  1.00 67.74  ? 497  GLU   A CG    1 
ATOM   2161  C  CD    . GLU   C 3 204 ? 44.004  53.558  21.685  1.00 71.27  ? 497  GLU   A CD    1 
ATOM   2162  O  OE1   . GLU   C 3 204 ? 43.956  54.754  22.080  1.00 69.25  ? 497  GLU   A OE1   1 
ATOM   2163  O  OE2   . GLU   C 3 204 ? 45.034  53.021  21.195  1.00 64.80  ? 497  GLU   A OE2   1 
ATOM   2164  N  N     . LEU   C 3 205 ? 38.727  54.729  22.070  1.00 76.57  ? 498  LEU   A N     1 
ATOM   2165  C  CA    . LEU   C 3 205 ? 37.721  55.675  22.535  1.00 78.18  ? 498  LEU   A CA    1 
ATOM   2166  C  C     . LEU   C 3 205 ? 36.315  55.171  22.205  1.00 75.56  ? 498  LEU   A C     1 
ATOM   2167  O  O     . LEU   C 3 205 ? 35.338  55.714  22.722  1.00 67.75  ? 498  LEU   A O     1 
ATOM   2168  C  CB    . LEU   C 3 205 ? 37.979  57.042  21.895  1.00 79.30  ? 498  LEU   A CB    1 
ATOM   2169  C  CG    . LEU   C 3 205 ? 39.288  57.721  22.289  1.00 81.16  ? 498  LEU   A CG    1 
ATOM   2170  C  CD1   . LEU   C 3 205 ? 39.427  59.059  21.580  1.00 81.18  ? 498  LEU   A CD1   1 
ATOM   2171  C  CD2   . LEU   C 3 205 ? 39.367  57.906  23.797  1.00 80.00  ? 498  LEU   A CD2   1 
ATOM   2172  N  N     . GLY   C 3 206 ? 36.233  54.170  21.311  1.00 75.28  ? 499  GLY   A N     1 
ATOM   2173  C  CA    . GLY   C 3 206 ? 35.015  53.406  21.082  1.00 83.75  ? 499  GLY   A CA    1 
ATOM   2174  C  C     . GLY   C 3 206 ? 33.915  54.184  20.358  1.00 85.01  ? 499  GLY   A C     1 
ATOM   2175  O  O     . GLY   C 3 206 ? 32.749  53.817  20.462  1.00 83.40  ? 499  GLY   A O     1 
ATOM   2176  N  N     . LEU   C 3 207 ? 34.287  55.235  19.611  1.00 92.71  ? 500  LEU   A N     1 
ATOM   2177  C  CA    . LEU   C 3 207 ? 33.322  56.124  18.975  1.00 90.02  ? 500  LEU   A CA    1 
ATOM   2178  C  C     . LEU   C 3 207 ? 32.664  55.432  17.782  1.00 87.85  ? 500  LEU   A C     1 
ATOM   2179  O  O     . LEU   C 3 207 ? 33.288  54.594  17.131  1.00 83.70  ? 500  LEU   A O     1 
ATOM   2180  C  CB    . LEU   C 3 207 ? 34.036  57.402  18.519  1.00 88.50  ? 500  LEU   A CB    1 
ATOM   2181  C  CG    . LEU   C 3 207 ? 34.683  58.230  19.626  1.00 90.75  ? 500  LEU   A CG    1 
ATOM   2182  C  CD1   . LEU   C 3 207 ? 35.308  59.497  19.059  1.00 92.36  ? 500  LEU   A CD1   1 
ATOM   2183  C  CD2   . LEU   C 3 207 ? 33.673  58.574  20.710  1.00 93.64  ? 500  LEU   A CD2   1 
ATOM   2184  N  N     . PRO   C 3 208 ? 31.394  55.769  17.447  1.00 90.17  ? 501  PRO   A N     1 
ATOM   2185  C  CA    . PRO   C 3 208 ? 30.693  55.116  16.339  1.00 90.17  ? 501  PRO   A CA    1 
ATOM   2186  C  C     . PRO   C 3 208 ? 31.372  55.368  14.989  1.00 90.62  ? 501  PRO   A C     1 
ATOM   2187  O  O     . PRO   C 3 208 ? 31.789  56.488  14.691  1.00 85.60  ? 501  PRO   A O     1 
ATOM   2188  C  CB    . PRO   C 3 208 ? 29.270  55.701  16.397  1.00 88.94  ? 501  PRO   A CB    1 
ATOM   2189  C  CG    . PRO   C 3 208 ? 29.417  57.008  17.153  1.00 89.43  ? 501  PRO   A CG    1 
ATOM   2190  C  CD    . PRO   C 3 208 ? 30.566  56.788  18.116  1.00 88.76  ? 501  PRO   A CD    1 
ATOM   2191  N  N     . ALA   C 3 209 ? 31.465  54.294  14.188  1.00 92.78  ? 502  ALA   A N     1 
ATOM   2192  C  CA    . ALA   C 3 209 ? 32.176  54.280  12.917  1.00 94.46  ? 502  ALA   A CA    1 
ATOM   2193  C  C     . ALA   C 3 209 ? 31.179  54.288  11.757  1.00 92.99  ? 502  ALA   A C     1 
ATOM   2194  O  O     . ALA   C 3 209 ? 30.738  53.236  11.301  1.00 82.97  ? 502  ALA   A O     1 
ATOM   2195  C  CB    . ALA   C 3 209 ? 33.070  53.064  12.860  1.00 93.95  ? 502  ALA   A CB    1 
ATOM   2196  N  N     . ILE   C 3 210 ? 30.882  55.488  11.247  1.00 99.77  ? 503  ILE   A N     1 
ATOM   2197  C  CA    . ILE   C 3 210 ? 29.693  55.728  10.444  1.00 97.90  ? 503  ILE   A CA    1 
ATOM   2198  C  C     . ILE   C 3 210 ? 29.896  55.289  8.991   1.00 93.79  ? 503  ILE   A C     1 
ATOM   2199  O  O     . ILE   C 3 210 ? 28.943  54.831  8.367   1.00 90.46  ? 503  ILE   A O     1 
ATOM   2200  C  CB    . ILE   C 3 210 ? 29.273  57.207  10.592  1.00 101.51 ? 503  ILE   A CB    1 
ATOM   2201  C  CG1   . ILE   C 3 210 ? 28.535  57.412  11.920  1.00 105.18 ? 503  ILE   A CG1   1 
ATOM   2202  C  CG2   . ILE   C 3 210 ? 28.454  57.700  9.403   1.00 96.03  ? 503  ILE   A CG2   1 
ATOM   2203  C  CD1   . ILE   C 3 210 ? 28.541  58.836  12.423  1.00 112.49 ? 503  ILE   A CD1   1 
ATOM   2204  N  N     . GLY   C 3 211 ? 31.119  55.410  8.452   1.00 89.97  ? 504  GLY   A N     1 
ATOM   2205  C  CA    . GLY   C 3 211 ? 31.359  55.132  7.041   1.00 80.95  ? 504  GLY   A CA    1 
ATOM   2206  C  C     . GLY   C 3 211 ? 32.544  54.198  6.811   1.00 72.16  ? 504  GLY   A C     1 
ATOM   2207  O  O     . GLY   C 3 211 ? 33.321  53.946  7.723   1.00 74.99  ? 504  GLY   A O     1 
ATOM   2208  N  N     . LYS   C 3 212 ? 32.669  53.690  5.579   1.00 74.39  ? 505  LYS   A N     1 
ATOM   2209  C  CA    . LYS   C 3 212 ? 33.789  52.849  5.182   1.00 78.05  ? 505  LYS   A CA    1 
ATOM   2210  C  C     . LYS   C 3 212 ? 34.677  53.604  4.191   1.00 70.44  ? 505  LYS   A C     1 
ATOM   2211  O  O     . LYS   C 3 212 ? 34.254  54.604  3.607   1.00 66.44  ? 505  LYS   A O     1 
ATOM   2212  C  CB    . LYS   C 3 212 ? 33.291  51.548  4.542   1.00 91.68  ? 505  LYS   A CB    1 
ATOM   2213  C  CG    . LYS   C 3 212 ? 32.488  50.615  5.451   1.00 99.85  ? 505  LYS   A CG    1 
ATOM   2214  C  CD    . LYS   C 3 212 ? 31.776  49.497  4.679   1.00 106.68 ? 505  LYS   A CD    1 
ATOM   2215  C  CE    . LYS   C 3 212 ? 32.738  48.565  3.918   1.00 104.48 ? 505  LYS   A CE    1 
ATOM   2216  N  NZ    . LYS   C 3 212 ? 33.744  47.939  4.848   1.00 106.91 ? 505  LYS   A NZ    1 
ATOM   2217  N  N     . THR   C 3 213 ? 35.918  53.121  4.023   1.00 64.31  ? 506  THR   A N     1 
ATOM   2218  C  CA    . THR   C 3 213 ? 36.812  53.626  2.991   1.00 63.78  ? 506  THR   A CA    1 
ATOM   2219  C  C     . THR   C 3 213 ? 36.461  52.894  1.704   1.00 67.80  ? 506  THR   A C     1 
ATOM   2220  O  O     . THR   C 3 213 ? 35.815  51.848  1.747   1.00 68.87  ? 506  THR   A O     1 
ATOM   2221  C  CB    . THR   C 3 213 ? 38.303  53.498  3.359   1.00 59.22  ? 506  THR   A CB    1 
ATOM   2222  O  OG1   . THR   C 3 213 ? 38.816  52.186  3.116   1.00 57.76  ? 506  THR   A OG1   1 
ATOM   2223  C  CG2   . THR   C 3 213 ? 38.586  53.854  4.801   1.00 59.82  ? 506  THR   A CG2   1 
ATOM   2224  N  N     . GLU   C 3 214 ? 36.911  53.445  0.574   1.00 72.29  ? 507  GLU   A N     1 
ATOM   2225  C  CA    . GLU   C 3 214 ? 36.458  52.991  -0.729  1.00 72.24  ? 507  GLU   A CA    1 
ATOM   2226  C  C     . GLU   C 3 214 ? 36.945  51.574  -1.010  1.00 72.00  ? 507  GLU   A C     1 
ATOM   2227  O  O     . GLU   C 3 214 ? 36.141  50.717  -1.355  1.00 89.95  ? 507  GLU   A O     1 
ATOM   2228  C  CB    . GLU   C 3 214 ? 36.943  53.927  -1.836  1.00 75.26  ? 507  GLU   A CB    1 
ATOM   2229  C  CG    . GLU   C 3 214 ? 36.375  55.331  -1.742  1.00 72.36  ? 507  GLU   A CG    1 
ATOM   2230  C  CD    . GLU   C 3 214 ? 36.683  56.206  -2.945  1.00 77.44  ? 507  GLU   A CD    1 
ATOM   2231  O  OE1   . GLU   C 3 214 ? 37.152  55.659  -3.988  1.00 71.59  ? 507  GLU   A OE1   1 
ATOM   2232  O  OE2   . GLU   C 3 214 ? 36.468  57.434  -2.833  1.00 70.62  ? 507  GLU   A OE2   1 
ATOM   2233  N  N     . LYS   C 3 215 ? 38.254  51.341  -0.867  1.00 67.61  ? 508  LYS   A N     1 
ATOM   2234  C  CA    . LYS   C 3 215 ? 38.911  50.214  -1.515  1.00 73.13  ? 508  LYS   A CA    1 
ATOM   2235  C  C     . LYS   C 3 215 ? 39.534  49.236  -0.515  1.00 77.48  ? 508  LYS   A C     1 
ATOM   2236  O  O     . LYS   C 3 215 ? 39.757  48.080  -0.870  1.00 77.14  ? 508  LYS   A O     1 
ATOM   2237  C  CB    . LYS   C 3 215 ? 39.971  50.736  -2.489  1.00 75.74  ? 508  LYS   A CB    1 
ATOM   2238  C  CG    . LYS   C 3 215 ? 39.443  51.734  -3.516  1.00 79.44  ? 508  LYS   A CG    1 
ATOM   2239  C  CD    . LYS   C 3 215 ? 40.312  51.896  -4.739  1.00 80.56  ? 508  LYS   A CD    1 
ATOM   2240  C  CE    . LYS   C 3 215 ? 40.277  50.680  -5.641  1.00 85.73  ? 508  LYS   A CE    1 
ATOM   2241  N  NZ    . LYS   C 3 215 ? 41.147  50.855  -6.830  1.00 83.57  ? 508  LYS   A NZ    1 
ATOM   2242  N  N     . THR   C 3 216 ? 39.826  49.693  0.713   1.00 78.19  ? 509  THR   A N     1 
ATOM   2243  C  CA    . THR   C 3 216 ? 40.470  48.866  1.726   1.00 78.89  ? 509  THR   A CA    1 
ATOM   2244  C  C     . THR   C 3 216 ? 39.429  48.326  2.709   1.00 77.88  ? 509  THR   A C     1 
ATOM   2245  O  O     . THR   C 3 216 ? 39.750  47.500  3.562   1.00 74.07  ? 509  THR   A O     1 
ATOM   2246  C  CB    . THR   C 3 216 ? 41.574  49.641  2.467   1.00 77.20  ? 509  THR   A CB    1 
ATOM   2247  O  OG1   . THR   C 3 216 ? 41.035  50.844  3.022   1.00 71.32  ? 509  THR   A OG1   1 
ATOM   2248  C  CG2   . THR   C 3 216 ? 42.748  49.978  1.573   1.00 76.22  ? 509  THR   A CG2   1 
ATOM   2249  N  N     . GLY   C 3 217 ? 38.186  48.808  2.584   1.00 72.51  ? 510  GLY   A N     1 
ATOM   2250  C  CA    . GLY   C 3 217 ? 37.124  48.447  3.502   1.00 72.58  ? 510  GLY   A CA    1 
ATOM   2251  C  C     . GLY   C 3 217 ? 37.560  48.554  4.961   1.00 75.90  ? 510  GLY   A C     1 
ATOM   2252  O  O     . GLY   C 3 217 ? 37.520  47.569  5.691   1.00 75.97  ? 510  GLY   A O     1 
ATOM   2253  N  N     . LYS   C 3 218 ? 37.970  49.758  5.379   1.00 75.89  ? 511  LYS   A N     1 
ATOM   2254  C  CA    . LYS   C 3 218 ? 38.223  50.039  6.784   1.00 70.48  ? 511  LYS   A CA    1 
ATOM   2255  C  C     . LYS   C 3 218 ? 37.233  51.101  7.244   1.00 65.89  ? 511  LYS   A C     1 
ATOM   2256  O  O     . LYS   C 3 218 ? 36.520  51.663  6.421   1.00 63.20  ? 511  LYS   A O     1 
ATOM   2257  C  CB    . LYS   C 3 218 ? 39.687  50.445  6.975   1.00 74.75  ? 511  LYS   A CB    1 
ATOM   2258  C  CG    . LYS   C 3 218 ? 40.685  49.326  6.688   1.00 81.58  ? 511  LYS   A CG    1 
ATOM   2259  C  CD    . LYS   C 3 218 ? 42.011  49.464  7.435   1.00 91.51  ? 511  LYS   A CD    1 
ATOM   2260  C  CE    . LYS   C 3 218 ? 42.525  48.170  8.042   1.00 95.83  ? 511  LYS   A CE    1 
ATOM   2261  N  NZ    . LYS   C 3 218 ? 42.586  47.072  7.041   1.00 95.33  ? 511  LYS   A NZ    1 
ATOM   2262  N  N     . ARG   C 3 219 ? 37.172  51.359  8.555   1.00 64.00  ? 512  ARG   A N     1 
ATOM   2263  C  CA    . ARG   C 3 219 ? 36.351  52.451  9.063   1.00 68.68  ? 512  ARG   A CA    1 
ATOM   2264  C  C     . ARG   C 3 219 ? 37.009  53.791  8.719   1.00 64.83  ? 512  ARG   A C     1 
ATOM   2265  O  O     . ARG   C 3 219 ? 38.211  53.961  8.921   1.00 61.30  ? 512  ARG   A O     1 
ATOM   2266  C  CB    . ARG   C 3 219 ? 36.136  52.308  10.573  1.00 72.38  ? 512  ARG   A CB    1 
ATOM   2267  C  CG    . ARG   C 3 219 ? 35.326  51.081  10.980  1.00 75.75  ? 512  ARG   A CG    1 
ATOM   2268  C  CD    . ARG   C 3 219 ? 35.602  50.680  12.419  1.00 74.74  ? 512  ARG   A CD    1 
ATOM   2269  N  NE    . ARG   C 3 219 ? 36.974  50.208  12.576  1.00 70.23  ? 512  ARG   A NE    1 
ATOM   2270  C  CZ    . ARG   C 3 219 ? 37.569  49.982  13.742  1.00 67.27  ? 512  ARG   A CZ    1 
ATOM   2271  N  NH1   . ARG   C 3 219 ? 36.966  50.307  14.870  1.00 59.91  ? 512  ARG   A NH1   1 
ATOM   2272  N  NH2   . ARG   C 3 219 ? 38.773  49.442  13.773  1.00 65.83  ? 512  ARG   A NH2   1 
ATOM   2273  N  N     . SER   C 3 220 ? 36.204  54.740  8.217   1.00 62.61  ? 513  SER   A N     1 
ATOM   2274  C  CA    . SER   C 3 220 ? 36.708  55.977  7.634   1.00 62.53  ? 513  SER   A CA    1 
ATOM   2275  C  C     . SER   C 3 220 ? 36.900  57.036  8.719   1.00 59.62  ? 513  SER   A C     1 
ATOM   2276  O  O     . SER   C 3 220 ? 36.074  57.159  9.622   1.00 57.93  ? 513  SER   A O     1 
ATOM   2277  C  CB    . SER   C 3 220 ? 35.803  56.498  6.522   1.00 60.76  ? 513  SER   A CB    1 
ATOM   2278  O  OG    . SER   C 3 220 ? 36.335  57.688  5.924   1.00 53.38  ? 513  SER   A OG    1 
ATOM   2279  N  N     . THR   C 3 221 ? 37.985  57.815  8.573   1.00 57.99  ? 514  THR   A N     1 
ATOM   2280  C  CA    . THR   C 3 221 ? 38.313  58.924  9.456   1.00 56.33  ? 514  THR   A CA    1 
ATOM   2281  C  C     . THR   C 3 221 ? 38.079  60.257  8.735   1.00 56.58  ? 514  THR   A C     1 
ATOM   2282  O  O     . THR   C 3 221 ? 38.487  61.312  9.225   1.00 55.77  ? 514  THR   A O     1 
ATOM   2283  C  CB    . THR   C 3 221 ? 39.751  58.755  9.975   1.00 58.35  ? 514  THR   A CB    1 
ATOM   2284  O  OG1   . THR   C 3 221 ? 40.671  58.784  8.881   1.00 53.78  ? 514  THR   A OG1   1 
ATOM   2285  C  CG2   . THR   C 3 221 ? 39.951  57.448  10.713  1.00 58.91  ? 514  THR   A CG2   1 
ATOM   2286  N  N     . SER   C 3 222 ? 37.374  60.209  7.593   1.00 56.04  ? 515  SER   A N     1 
ATOM   2287  C  CA    . SER   C 3 222 ? 37.160  61.378  6.757   1.00 54.20  ? 515  SER   A CA    1 
ATOM   2288  C  C     . SER   C 3 222 ? 36.237  62.345  7.478   1.00 51.86  ? 515  SER   A C     1 
ATOM   2289  O  O     . SER   C 3 222 ? 35.554  61.938  8.406   1.00 56.98  ? 515  SER   A O     1 
ATOM   2290  C  CB    . SER   C 3 222 ? 36.616  61.004  5.400   1.00 54.75  ? 515  SER   A CB    1 
ATOM   2291  O  OG    . SER   C 3 222 ? 35.311  60.469  5.508   1.00 57.15  ? 515  SER   A OG    1 
ATOM   2292  N  N     . ALA   C 3 223 ? 36.252  63.612  7.047   1.00 53.03  ? 516  ALA   A N     1 
ATOM   2293  C  CA    . ALA   C 3 223 ? 35.443  64.669  7.636   1.00 54.68  ? 516  ALA   A CA    1 
ATOM   2294  C  C     . ALA   C 3 223 ? 33.962  64.305  7.567   1.00 58.15  ? 516  ALA   A C     1 
ATOM   2295  O  O     . ALA   C 3 223 ? 33.185  64.744  8.412   1.00 62.75  ? 516  ALA   A O     1 
ATOM   2296  C  CB    . ALA   C 3 223 ? 35.700  65.985  6.935   1.00 53.65  ? 516  ALA   A CB    1 
ATOM   2297  N  N     . ALA   C 3 224 ? 33.590  63.528  6.543   1.00 66.78  ? 517  ALA   A N     1 
ATOM   2298  C  CA    . ALA   C 3 224 ? 32.229  63.035  6.384   1.00 72.80  ? 517  ALA   A CA    1 
ATOM   2299  C  C     . ALA   C 3 224 ? 31.855  62.186  7.594   1.00 68.61  ? 517  ALA   A C     1 
ATOM   2300  O  O     . ALA   C 3 224 ? 30.871  62.482  8.266   1.00 72.25  ? 517  ALA   A O     1 
ATOM   2301  C  CB    . ALA   C 3 224 ? 32.102  62.240  5.100   1.00 69.97  ? 517  ALA   A CB    1 
ATOM   2302  N  N     . ALA   C 3 225 ? 32.694  61.175  7.875   1.00 67.25  ? 518  ALA   A N     1 
ATOM   2303  C  CA    . ALA   C 3 225 ? 32.472  60.201  8.937   1.00 66.00  ? 518  ALA   A CA    1 
ATOM   2304  C  C     . ALA   C 3 225 ? 32.588  60.807  10.340  1.00 65.26  ? 518  ALA   A C     1 
ATOM   2305  O  O     . ALA   C 3 225 ? 32.144  60.184  11.304  1.00 70.41  ? 518  ALA   A O     1 
ATOM   2306  C  CB    . ALA   C 3 225 ? 33.436  59.053  8.773   1.00 61.76  ? 518  ALA   A CB    1 
ATOM   2307  N  N     . LEU   C 3 226 ? 33.188  62.000  10.464  1.00 69.39  ? 519  LEU   A N     1 
ATOM   2308  C  CA    . LEU   C 3 226 ? 33.482  62.584  11.765  1.00 66.68  ? 519  LEU   A CA    1 
ATOM   2309  C  C     . LEU   C 3 226 ? 32.654  63.841  12.009  1.00 68.60  ? 519  LEU   A C     1 
ATOM   2310  O  O     . LEU   C 3 226 ? 32.764  64.426  13.084  1.00 70.84  ? 519  LEU   A O     1 
ATOM   2311  C  CB    . LEU   C 3 226 ? 34.971  62.946  11.844  1.00 65.52  ? 519  LEU   A CB    1 
ATOM   2312  C  CG    . LEU   C 3 226 ? 35.979  61.806  11.700  1.00 65.80  ? 519  LEU   A CG    1 
ATOM   2313  C  CD1   . LEU   C 3 226 ? 37.379  62.278  12.068  1.00 64.75  ? 519  LEU   A CD1   1 
ATOM   2314  C  CD2   . LEU   C 3 226 ? 35.585  60.604  12.542  1.00 70.33  ? 519  LEU   A CD2   1 
ATOM   2315  N  N     . GLU   C 3 227 ? 31.855  64.269  11.022  1.00 73.53  ? 520  GLU   A N     1 
ATOM   2316  C  CA    . GLU   C 3 227 ? 31.155  65.543  11.116  1.00 80.21  ? 520  GLU   A CA    1 
ATOM   2317  C  C     . GLU   C 3 227 ? 30.175  65.543  12.293  1.00 79.84  ? 520  GLU   A C     1 
ATOM   2318  O  O     . GLU   C 3 227 ? 30.178  66.481  13.086  1.00 78.50  ? 520  GLU   A O     1 
ATOM   2319  C  CB    . GLU   C 3 227 ? 30.430  65.904  9.812   1.00 79.96  ? 520  GLU   A CB    1 
ATOM   2320  C  CG    . GLU   C 3 227 ? 30.998  67.138  9.124   1.00 80.44  ? 520  GLU   A CG    1 
ATOM   2321  C  CD    . GLU   C 3 227 ? 30.923  68.420  9.945   1.00 79.33  ? 520  GLU   A CD    1 
ATOM   2322  O  OE1   . GLU   C 3 227 ? 31.969  69.067  10.127  1.00 81.21  ? 520  GLU   A OE1   1 
ATOM   2323  O  OE2   . GLU   C 3 227 ? 29.823  68.768  10.417  1.00 71.95  ? 520  GLU   A OE2   1 
ATOM   2324  N  N     . ALA   C 3 228 ? 29.341  64.499  12.397  1.00 84.35  ? 521  ALA   A N     1 
ATOM   2325  C  CA    . ALA   C 3 228 ? 28.302  64.434  13.419  1.00 86.52  ? 521  ALA   A CA    1 
ATOM   2326  C  C     . ALA   C 3 228 ? 28.920  64.355  14.817  1.00 82.23  ? 521  ALA   A C     1 
ATOM   2327  O  O     . ALA   C 3 228 ? 28.309  64.807  15.781  1.00 77.37  ? 521  ALA   A O     1 
ATOM   2328  C  CB    . ALA   C 3 228 ? 27.373  63.263  13.160  1.00 85.43  ? 521  ALA   A CB    1 
ATOM   2329  N  N     . LEU   C 3 229 ? 30.147  63.820  14.902  1.00 81.60  ? 522  LEU   A N     1 
ATOM   2330  C  CA    . LEU   C 3 229 ? 30.816  63.548  16.165  1.00 77.56  ? 522  LEU   A CA    1 
ATOM   2331  C  C     . LEU   C 3 229 ? 31.532  64.783  16.722  1.00 80.36  ? 522  LEU   A C     1 
ATOM   2332  O  O     . LEU   C 3 229 ? 32.084  64.706  17.813  1.00 81.00  ? 522  LEU   A O     1 
ATOM   2333  C  CB    . LEU   C 3 229 ? 31.809  62.405  15.932  1.00 74.03  ? 522  LEU   A CB    1 
ATOM   2334  C  CG    . LEU   C 3 229 ? 31.202  61.006  15.831  1.00 77.40  ? 522  LEU   A CG    1 
ATOM   2335  C  CD1   . LEU   C 3 229 ? 30.323  60.862  14.599  1.00 85.12  ? 522  LEU   A CD1   1 
ATOM   2336  C  CD2   . LEU   C 3 229 ? 32.297  59.950  15.811  1.00 78.56  ? 522  LEU   A CD2   1 
ATOM   2337  N  N     . ARG   C 3 230 ? 31.511  65.917  16.001  1.00 87.24  ? 523  ARG   A N     1 
ATOM   2338  C  CA    . ARG   C 3 230 ? 32.368  67.059  16.306  1.00 91.76  ? 523  ARG   A CA    1 
ATOM   2339  C  C     . ARG   C 3 230 ? 32.009  67.709  17.642  1.00 95.77  ? 523  ARG   A C     1 
ATOM   2340  O  O     . ARG   C 3 230 ? 32.894  67.956  18.458  1.00 97.82  ? 523  ARG   A O     1 
ATOM   2341  C  CB    . ARG   C 3 230 ? 32.267  68.161  15.242  1.00 94.67  ? 523  ARG   A CB    1 
ATOM   2342  C  CG    . ARG   C 3 230 ? 33.036  67.904  13.953  1.00 94.49  ? 523  ARG   A CG    1 
ATOM   2343  C  CD    . ARG   C 3 230 ? 32.881  69.033  12.941  1.00 91.66  ? 523  ARG   A CD    1 
ATOM   2344  N  NE    . ARG   C 3 230 ? 33.823  70.140  13.118  1.00 91.92  ? 523  ARG   A NE    1 
ATOM   2345  C  CZ    . ARG   C 3 230 ? 34.702  70.551  12.200  1.00 90.78  ? 523  ARG   A CZ    1 
ATOM   2346  N  NH1   . ARG   C 3 230 ? 35.790  71.215  12.553  1.00 80.23  ? 523  ARG   A NH1   1 
ATOM   2347  N  NH2   . ARG   C 3 230 ? 34.517  70.262  10.924  1.00 91.48  ? 523  ARG   A NH2   1 
ATOM   2348  N  N     . GLU   C 3 231 ? 30.727  68.054  17.827  1.00 103.26 ? 524  GLU   A N     1 
ATOM   2349  C  CA    . GLU   C 3 231 ? 30.320  68.924  18.924  1.00 105.99 ? 524  GLU   A CA    1 
ATOM   2350  C  C     . GLU   C 3 231 ? 30.384  68.172  20.253  1.00 103.06 ? 524  GLU   A C     1 
ATOM   2351  O  O     . GLU   C 3 231 ? 30.745  68.759  21.272  1.00 92.51  ? 524  GLU   A O     1 
ATOM   2352  C  CB    . GLU   C 3 231 ? 28.919  69.501  18.699  1.00 108.07 ? 524  GLU   A CB    1 
ATOM   2353  C  CG    . GLU   C 3 231 ? 28.932  70.923  18.165  1.00 111.36 ? 524  GLU   A CG    1 
ATOM   2354  C  CD    . GLU   C 3 231 ? 27.563  71.574  18.048  1.00 112.94 ? 524  GLU   A CD    1 
ATOM   2355  O  OE1   . GLU   C 3 231 ? 26.549  70.879  18.272  1.00 112.91 ? 524  GLU   A OE1   1 
ATOM   2356  O  OE2   . GLU   C 3 231 ? 27.513  72.781  17.740  1.00 110.23 ? 524  GLU   A OE2   1 
ATOM   2357  N  N     . ALA   C 3 232 ? 30.043  66.877  20.219  1.00 99.38  ? 525  ALA   A N     1 
ATOM   2358  C  CA    . ALA   C 3 232 ? 30.048  66.031  21.401  1.00 96.54  ? 525  ALA   A CA    1 
ATOM   2359  C  C     . ALA   C 3 232 ? 31.474  65.839  21.931  1.00 101.60 ? 525  ALA   A C     1 
ATOM   2360  O  O     . ALA   C 3 232 ? 31.722  66.054  23.120  1.00 92.55  ? 525  ALA   A O     1 
ATOM   2361  C  CB    . ALA   C 3 232 ? 29.381  64.713  21.075  1.00 94.23  ? 525  ALA   A CB    1 
ATOM   2362  N  N     . HIS   C 3 233 ? 32.410  65.473  21.036  1.00 98.93  ? 526  HIS   A N     1 
ATOM   2363  C  CA    . HIS   C 3 233 ? 33.738  65.000  21.419  1.00 94.99  ? 526  HIS   A CA    1 
ATOM   2364  C  C     . HIS   C 3 233 ? 34.825  66.009  21.027  1.00 89.53  ? 526  HIS   A C     1 
ATOM   2365  O  O     . HIS   C 3 233 ? 35.192  66.114  19.860  1.00 84.39  ? 526  HIS   A O     1 
ATOM   2366  C  CB    . HIS   C 3 233 ? 33.983  63.617  20.793  1.00 88.46  ? 526  HIS   A CB    1 
ATOM   2367  C  CG    . HIS   C 3 233 ? 32.860  62.649  21.022  1.00 92.72  ? 526  HIS   A CG    1 
ATOM   2368  N  ND1   . HIS   C 3 233 ? 31.654  62.699  20.359  1.00 94.23  ? 526  HIS   A ND1   1 
ATOM   2369  C  CD2   . HIS   C 3 233 ? 32.782  61.609  21.896  1.00 88.59  ? 526  HIS   A CD2   1 
ATOM   2370  C  CE1   . HIS   C 3 233 ? 30.867  61.718  20.796  1.00 92.93  ? 526  HIS   A CE1   1 
ATOM   2371  N  NE2   . HIS   C 3 233 ? 31.551  61.028  21.749  1.00 94.30  ? 526  HIS   A NE2   1 
ATOM   2372  N  N     . PRO   C 3 234 ? 35.385  66.784  21.988  1.00 86.07  ? 527  PRO   A N     1 
ATOM   2373  C  CA    . PRO   C 3 234 ? 36.467  67.730  21.696  1.00 84.20  ? 527  PRO   A CA    1 
ATOM   2374  C  C     . PRO   C 3 234 ? 37.666  67.211  20.899  1.00 77.14  ? 527  PRO   A C     1 
ATOM   2375  O  O     . PRO   C 3 234 ? 38.324  67.986  20.211  1.00 77.29  ? 527  PRO   A O     1 
ATOM   2376  C  CB    . PRO   C 3 234 ? 36.941  68.147  23.101  1.00 82.88  ? 527  PRO   A CB    1 
ATOM   2377  C  CG    . PRO   C 3 234 ? 35.682  68.079  23.933  1.00 83.83  ? 527  PRO   A CG    1 
ATOM   2378  C  CD    . PRO   C 3 234 ? 34.951  66.863  23.395  1.00 84.48  ? 527  PRO   A CD    1 
ATOM   2379  N  N     . ILE   C 3 235 ? 37.970  65.914  20.999  1.00 70.77  ? 528  ILE   A N     1 
ATOM   2380  C  CA    . ILE   C 3 235 ? 39.154  65.370  20.350  1.00 67.07  ? 528  ILE   A CA    1 
ATOM   2381  C  C     . ILE   C 3 235 ? 38.974  65.391  18.831  1.00 68.00  ? 528  ILE   A C     1 
ATOM   2382  O  O     . ILE   C 3 235 ? 39.935  65.620  18.092  1.00 57.24  ? 528  ILE   A O     1 
ATOM   2383  C  CB    . ILE   C 3 235 ? 39.464  63.945  20.850  1.00 65.37  ? 528  ILE   A CB    1 
ATOM   2384  C  CG1   . ILE   C 3 235 ? 40.904  63.545  20.504  1.00 65.99  ? 528  ILE   A CG1   1 
ATOM   2385  C  CG2   . ILE   C 3 235 ? 38.429  62.945  20.336  1.00 66.83  ? 528  ILE   A CG2   1 
ATOM   2386  C  CD1   . ILE   C 3 235 ? 41.184  62.055  20.531  1.00 64.80  ? 528  ILE   A CD1   1 
ATOM   2387  N  N     . VAL   C 3 236 ? 37.739  65.130  18.381  1.00 68.93  ? 529  VAL   A N     1 
ATOM   2388  C  CA    . VAL   C 3 236 ? 37.424  65.037  16.965  1.00 71.36  ? 529  VAL   A CA    1 
ATOM   2389  C  C     . VAL   C 3 236 ? 37.565  66.417  16.323  1.00 65.86  ? 529  VAL   A C     1 
ATOM   2390  O  O     . VAL   C 3 236 ? 38.147  66.538  15.249  1.00 63.45  ? 529  VAL   A O     1 
ATOM   2391  C  CB    . VAL   C 3 236 ? 36.027  64.419  16.760  1.00 76.24  ? 529  VAL   A CB    1 
ATOM   2392  C  CG1   . VAL   C 3 236 ? 35.536  64.560  15.326  1.00 79.34  ? 529  VAL   A CG1   1 
ATOM   2393  C  CG2   . VAL   C 3 236 ? 36.009  62.960  17.197  1.00 72.43  ? 529  VAL   A CG2   1 
ATOM   2394  N  N     . GLU   C 3 237 ? 37.076  67.458  17.009  1.00 66.09  ? 530  GLU   A N     1 
ATOM   2395  C  CA    . GLU   C 3 237 ? 37.246  68.834  16.561  1.00 67.03  ? 530  GLU   A CA    1 
ATOM   2396  C  C     . GLU   C 3 237 ? 38.731  69.161  16.373  1.00 62.96  ? 530  GLU   A C     1 
ATOM   2397  O  O     . GLU   C 3 237 ? 39.113  69.795  15.390  1.00 66.32  ? 530  GLU   A O     1 
ATOM   2398  C  CB    . GLU   C 3 237 ? 36.613  69.802  17.567  1.00 66.07  ? 530  GLU   A CB    1 
ATOM   2399  C  CG    . GLU   C 3 237 ? 36.526  71.249  17.087  1.00 75.53  ? 530  GLU   A CG    1 
ATOM   2400  C  CD    . GLU   C 3 237 ? 35.677  71.471  15.840  1.00 84.41  ? 530  GLU   A CD    1 
ATOM   2401  O  OE1   . GLU   C 3 237 ? 34.618  70.808  15.738  1.00 82.34  ? 530  GLU   A OE1   1 
ATOM   2402  O  OE2   . GLU   C 3 237 ? 36.095  72.269  14.953  1.00 82.03  ? 530  GLU   A OE2   1 
ATOM   2403  N  N     . LYS   C 3 238 ? 39.555  68.746  17.337  1.00 56.05  ? 531  LYS   A N     1 
ATOM   2404  C  CA    . LYS   C 3 238 ? 40.955  69.132  17.380  1.00 55.77  ? 531  LYS   A CA    1 
ATOM   2405  C  C     . LYS   C 3 238 ? 41.712  68.445  16.245  1.00 50.66  ? 531  LYS   A C     1 
ATOM   2406  O  O     . LYS   C 3 238 ? 42.621  69.029  15.672  1.00 49.05  ? 531  LYS   A O     1 
ATOM   2407  C  CB    . LYS   C 3 238 ? 41.546  68.757  18.742  1.00 61.47  ? 531  LYS   A CB    1 
ATOM   2408  C  CG    . LYS   C 3 238 ? 40.958  69.486  19.943  1.00 66.27  ? 531  LYS   A CG    1 
ATOM   2409  C  CD    . LYS   C 3 238 ? 41.852  70.567  20.513  1.00 73.99  ? 531  LYS   A CD    1 
ATOM   2410  C  CE    . LYS   C 3 238 ? 41.340  71.137  21.823  1.00 71.50  ? 531  LYS   A CE    1 
ATOM   2411  N  NZ    . LYS   C 3 238 ? 40.281  72.145  21.595  1.00 70.50  ? 531  LYS   A NZ    1 
ATOM   2412  N  N     . ILE   C 3 239 ? 41.331  67.199  15.938  1.00 48.42  ? 532  ILE   A N     1 
ATOM   2413  C  CA    . ILE   C 3 239 ? 41.950  66.425  14.873  1.00 52.03  ? 532  ILE   A CA    1 
ATOM   2414  C  C     . ILE   C 3 239 ? 41.635  67.054  13.512  1.00 51.24  ? 532  ILE   A C     1 
ATOM   2415  O  O     . ILE   C 3 239 ? 42.524  67.201  12.679  1.00 55.30  ? 532  ILE   A O     1 
ATOM   2416  C  CB    . ILE   C 3 239 ? 41.514  64.948  14.981  1.00 58.67  ? 532  ILE   A CB    1 
ATOM   2417  C  CG1   . ILE   C 3 239 ? 42.287  64.233  16.095  1.00 60.01  ? 532  ILE   A CG1   1 
ATOM   2418  C  CG2   . ILE   C 3 239 ? 41.655  64.207  13.654  1.00 62.60  ? 532  ILE   A CG2   1 
ATOM   2419  C  CD1   . ILE   C 3 239 ? 41.613  62.975  16.602  1.00 62.16  ? 532  ILE   A CD1   1 
ATOM   2420  N  N     . LEU   C 3 240 ? 40.378  67.439  13.286  1.00 52.52  ? 533  LEU   A N     1 
ATOM   2421  C  CA    . LEU   C 3 240 ? 39.994  68.089  12.040  1.00 55.54  ? 533  LEU   A CA    1 
ATOM   2422  C  C     . LEU   C 3 240 ? 40.733  69.417  11.879  1.00 51.85  ? 533  LEU   A C     1 
ATOM   2423  O  O     . LEU   C 3 240 ? 41.223  69.715  10.789  1.00 56.05  ? 533  LEU   A O     1 
ATOM   2424  C  CB    . LEU   C 3 240 ? 38.470  68.265  12.001  1.00 59.15  ? 533  LEU   A CB    1 
ATOM   2425  C  CG    . LEU   C 3 240 ? 37.670  66.958  11.967  1.00 61.32  ? 533  LEU   A CG    1 
ATOM   2426  C  CD1   . LEU   C 3 240 ? 36.178  67.223  11.850  1.00 63.86  ? 533  LEU   A CD1   1 
ATOM   2427  C  CD2   . LEU   C 3 240 ? 38.129  66.054  10.830  1.00 63.07  ? 533  LEU   A CD2   1 
ATOM   2428  N  N     . GLN   C 3 241 ? 40.873  70.192  12.963  1.00 46.66  ? 534  GLN   A N     1 
ATOM   2429  C  CA    . GLN   C 3 241 ? 41.644  71.428  12.878  1.00 48.33  ? 534  GLN   A CA    1 
ATOM   2430  C  C     . GLN   C 3 241 ? 43.120  71.133  12.560  1.00 46.67  ? 534  GLN   A C     1 
ATOM   2431  O  O     . GLN   C 3 241 ? 43.755  71.872  11.803  1.00 42.96  ? 534  GLN   A O     1 
ATOM   2432  C  CB    . GLN   C 3 241 ? 41.527  72.244  14.167  1.00 50.89  ? 534  GLN   A CB    1 
ATOM   2433  C  CG    . GLN   C 3 241 ? 40.145  72.817  14.420  1.00 52.03  ? 534  GLN   A CG    1 
ATOM   2434  C  CD    . GLN   C 3 241 ? 39.995  73.405  15.805  1.00 57.65  ? 534  GLN   A CD    1 
ATOM   2435  O  OE1   . GLN   C 3 241 ? 38.902  73.434  16.364  1.00 63.95  ? 534  GLN   A OE1   1 
ATOM   2436  N  NE2   . GLN   C 3 241 ? 41.088  73.870  16.384  1.00 52.27  ? 534  GLN   A NE2   1 
ATOM   2437  N  N     . TYR   C 3 242 ? 43.669  70.061  13.158  1.00 47.02  ? 535  TYR   A N     1 
ATOM   2438  C  CA    . TYR   C 3 242 ? 45.060  69.653  12.944  1.00 47.71  ? 535  TYR   A CA    1 
ATOM   2439  C  C     . TYR   C 3 242 ? 45.276  69.338  11.466  1.00 42.66  ? 535  TYR   A C     1 
ATOM   2440  O  O     . TYR   C 3 242 ? 46.271  69.748  10.860  1.00 44.70  ? 535  TYR   A O     1 
ATOM   2441  C  CB    . TYR   C 3 242 ? 45.422  68.428  13.804  1.00 45.18  ? 535  TYR   A CB    1 
ATOM   2442  C  CG    . TYR   C 3 242 ? 46.805  67.867  13.576  1.00 44.69  ? 535  TYR   A CG    1 
ATOM   2443  C  CD1   . TYR   C 3 242 ? 47.914  68.358  14.250  1.00 43.98  ? 535  TYR   A CD1   1 
ATOM   2444  C  CD2   . TYR   C 3 242 ? 47.012  66.847  12.659  1.00 44.22  ? 535  TYR   A CD2   1 
ATOM   2445  C  CE1   . TYR   C 3 242 ? 49.185  67.845  14.023  1.00 45.52  ? 535  TYR   A CE1   1 
ATOM   2446  C  CE2   . TYR   C 3 242 ? 48.279  66.350  12.398  1.00 43.49  ? 535  TYR   A CE2   1 
ATOM   2447  C  CZ    . TYR   C 3 242 ? 49.369  66.841  13.091  1.00 46.53  ? 535  TYR   A CZ    1 
ATOM   2448  O  OH    . TYR   C 3 242 ? 50.617  66.311  12.853  1.00 53.38  ? 535  TYR   A OH    1 
ATOM   2449  N  N     . ARG   C 3 243 ? 44.331  68.573  10.912  1.00 45.80  ? 536  ARG   A N     1 
ATOM   2450  C  CA    . ARG   C 3 243 ? 44.370  68.179  9.513   1.00 44.51  ? 536  ARG   A CA    1 
ATOM   2451  C  C     . ARG   C 3 243 ? 44.405  69.401  8.605   1.00 41.62  ? 536  ARG   A C     1 
ATOM   2452  O  O     . ARG   C 3 243 ? 45.257  69.474  7.725   1.00 42.93  ? 536  ARG   A O     1 
ATOM   2453  C  CB    . ARG   C 3 243 ? 43.183  67.282  9.184   1.00 42.82  ? 536  ARG   A CB    1 
ATOM   2454  C  CG    . ARG   C 3 243 ? 43.458  65.820  9.492   1.00 44.80  ? 536  ARG   A CG    1 
ATOM   2455  C  CD    . ARG   C 3 243 ? 42.478  64.994  8.713   1.00 47.31  ? 536  ARG   A CD    1 
ATOM   2456  N  NE    . ARG   C 3 243 ? 42.593  63.588  9.016   1.00 45.90  ? 536  ARG   A NE    1 
ATOM   2457  C  CZ    . ARG   C 3 243 ? 41.570  62.757  9.074   1.00 46.84  ? 536  ARG   A CZ    1 
ATOM   2458  N  NH1   . ARG   C 3 243 ? 40.329  63.217  8.978   1.00 49.64  ? 536  ARG   A NH1   1 
ATOM   2459  N  NH2   . ARG   C 3 243 ? 41.804  61.465  9.210   1.00 50.60  ? 536  ARG   A NH2   1 
ATOM   2460  N  N     . GLU   C 3 244 ? 43.531  70.381  8.867   1.00 41.45  ? 537  GLU   A N     1 
ATOM   2461  C  CA    . GLU   C 3 244 ? 43.472  71.562  8.021   1.00 41.51  ? 537  GLU   A CA    1 
ATOM   2462  C  C     . GLU   C 3 244 ? 44.813  72.303  8.051   1.00 40.75  ? 537  GLU   A C     1 
ATOM   2463  O  O     . GLU   C 3 244 ? 45.372  72.636  6.997   1.00 40.40  ? 537  GLU   A O     1 
ATOM   2464  C  CB    . GLU   C 3 244 ? 42.323  72.482  8.430   1.00 43.35  ? 537  GLU   A CB    1 
ATOM   2465  C  CG    . GLU   C 3 244 ? 42.285  73.731  7.568   1.00 48.71  ? 537  GLU   A CG    1 
ATOM   2466  C  CD    . GLU   C 3 244 ? 41.359  74.835  8.018   1.00 48.17  ? 537  GLU   A CD    1 
ATOM   2467  O  OE1   . GLU   C 3 244 ? 40.527  74.585  8.892   1.00 63.46  ? 537  GLU   A OE1   1 
ATOM   2468  O  OE2   . GLU   C 3 244 ? 41.492  75.945  7.492   1.00 63.69  ? 537  GLU   A OE2   1 
ATOM   2469  N  N     . LEU   C 3 245 ? 45.322  72.579  9.262   1.00 42.09  ? 538  LEU   A N     1 
ATOM   2470  C  CA    . LEU   C 3 245 ? 46.560  73.334  9.420   1.00 38.11  ? 538  LEU   A CA    1 
ATOM   2471  C  C     . LEU   C 3 245 ? 47.720  72.607  8.754   1.00 32.73  ? 538  LEU   A C     1 
ATOM   2472  O  O     . LEU   C 3 245 ? 48.512  73.245  8.086   1.00 37.06  ? 538  LEU   A O     1 
ATOM   2473  C  CB    . LEU   C 3 245 ? 46.829  73.567  10.912  1.00 44.75  ? 538  LEU   A CB    1 
ATOM   2474  C  CG    . LEU   C 3 245 ? 46.199  74.810  11.556  1.00 48.88  ? 538  LEU   A CG    1 
ATOM   2475  C  CD1   . LEU   C 3 245 ? 44.811  75.128  11.010  1.00 59.42  ? 538  LEU   A CD1   1 
ATOM   2476  C  CD2   . LEU   C 3 245 ? 46.100  74.605  13.054  1.00 52.49  ? 538  LEU   A CD2   1 
ATOM   2477  N  N     . THR   C 3 246 ? 47.829  71.287  8.943   1.00 35.38  ? 539  THR   A N     1 
ATOM   2478  C  CA    . THR   C 3 246 ? 48.938  70.517  8.379   1.00 40.60  ? 539  THR   A CA    1 
ATOM   2479  C  C     . THR   C 3 246 ? 48.846  70.438  6.853   1.00 40.03  ? 539  THR   A C     1 
ATOM   2480  O  O     . THR   C 3 246 ? 49.862  70.457  6.156   1.00 44.09  ? 539  THR   A O     1 
ATOM   2481  C  CB    . THR   C 3 246 ? 49.017  69.106  8.987   1.00 43.38  ? 539  THR   A CB    1 
ATOM   2482  O  OG1   . THR   C 3 246 ? 47.697  68.595  9.158   1.00 47.31  ? 539  THR   A OG1   1 
ATOM   2483  C  CG2   . THR   C 3 246 ? 49.684  69.084  10.344  1.00 44.64  ? 539  THR   A CG2   1 
ATOM   2484  N  N     . LYS   C 3 247 ? 47.615  70.344  6.347   1.00 42.88  ? 540  LYS   A N     1 
ATOM   2485  C  CA    . LYS   C 3 247 ? 47.339  70.323  4.918   1.00 42.08  ? 540  LYS   A CA    1 
ATOM   2486  C  C     . LYS   C 3 247 ? 47.803  71.639  4.308   1.00 39.84  ? 540  LYS   A C     1 
ATOM   2487  O  O     . LYS   C 3 247 ? 48.587  71.651  3.351   1.00 36.64  ? 540  LYS   A O     1 
ATOM   2488  C  CB    . LYS   C 3 247 ? 45.832  70.135  4.710   1.00 46.02  ? 540  LYS   A CB    1 
ATOM   2489  C  CG    . LYS   C 3 247 ? 45.306  70.229  3.280   1.00 46.83  ? 540  LYS   A CG    1 
ATOM   2490  C  CD    . LYS   C 3 247 ? 45.497  68.947  2.553   1.00 47.66  ? 540  LYS   A CD    1 
ATOM   2491  C  CE    . LYS   C 3 247 ? 44.628  68.774  1.333   1.00 43.42  ? 540  LYS   A CE    1 
ATOM   2492  N  NZ    . LYS   C 3 247 ? 45.010  67.505  0.670   1.00 44.09  ? 540  LYS   A NZ    1 
ATOM   2493  N  N     . LEU   C 3 248 ? 47.304  72.748  4.878   1.00 38.54  ? 541  LEU   A N     1 
ATOM   2494  C  CA    . LEU   C 3 248 ? 47.567  74.059  4.302   1.00 36.51  ? 541  LEU   A CA    1 
ATOM   2495  C  C     . LEU   C 3 248 ? 49.054  74.383  4.412   1.00 36.23  ? 541  LEU   A C     1 
ATOM   2496  O  O     . LEU   C 3 248 ? 49.634  74.929  3.472   1.00 37.83  ? 541  LEU   A O     1 
ATOM   2497  C  CB    . LEU   C 3 248 ? 46.680  75.121  4.959   1.00 38.34  ? 541  LEU   A CB    1 
ATOM   2498  C  CG    . LEU   C 3 248 ? 45.163  74.945  4.782   1.00 43.11  ? 541  LEU   A CG    1 
ATOM   2499  C  CD1   . LEU   C 3 248 ? 44.437  76.279  4.764   1.00 42.37  ? 541  LEU   A CD1   1 
ATOM   2500  C  CD2   . LEU   C 3 248 ? 44.794  74.139  3.538   1.00 42.90  ? 541  LEU   A CD2   1 
ATOM   2501  N  N     . LYS   C 3 249 ? 49.694  73.960  5.509   1.00 37.59  ? 542  LYS   A N     1 
ATOM   2502  C  CA    . LYS   C 3 249 ? 51.104  74.274  5.717   1.00 39.89  ? 542  LYS   A CA    1 
ATOM   2503  C  C     . LYS   C 3 249 ? 51.991  73.528  4.718   1.00 37.29  ? 542  LYS   A C     1 
ATOM   2504  O  O     . LYS   C 3 249 ? 52.844  74.128  4.062   1.00 39.56  ? 542  LYS   A O     1 
ATOM   2505  C  CB    . LYS   C 3 249 ? 51.497  73.944  7.161   1.00 40.69  ? 542  LYS   A CB    1 
ATOM   2506  C  CG    . LYS   C 3 249 ? 52.964  74.154  7.506   1.00 39.36  ? 542  LYS   A CG    1 
ATOM   2507  C  CD    . LYS   C 3 249 ? 53.200  74.321  9.013   1.00 44.22  ? 542  LYS   A CD    1 
ATOM   2508  C  CE    . LYS   C 3 249 ? 54.566  73.853  9.476   1.00 42.68  ? 542  LYS   A CE    1 
ATOM   2509  N  NZ    . LYS   C 3 249 ? 55.662  74.447  8.672   1.00 44.31  ? 542  LYS   A NZ    1 
ATOM   2510  N  N     . SER   C 3 250 ? 51.796  72.205  4.626   1.00 39.06  ? 543  SER   A N     1 
ATOM   2511  C  CA    . SER   C 3 250 ? 52.599  71.341  3.770   1.00 39.69  ? 543  SER   A CA    1 
ATOM   2512  C  C     . SER   C 3 250 ? 52.320  71.559  2.279   1.00 38.50  ? 543  SER   A C     1 
ATOM   2513  O  O     . SER   C 3 250 ? 53.200  71.335  1.451   1.00 38.64  ? 543  SER   A O     1 
ATOM   2514  C  CB    . SER   C 3 250 ? 52.356  69.905  4.127   1.00 42.61  ? 543  SER   A CB    1 
ATOM   2515  O  OG    . SER   C 3 250 ? 51.019  69.533  3.802   1.00 47.88  ? 543  SER   A OG    1 
ATOM   2516  N  N     . THR   C 3 251 ? 51.085  71.933  1.909   1.00 37.25  ? 544  THR   A N     1 
ATOM   2517  C  CA    . THR   C 3 251 ? 50.736  72.010  0.496   1.00 33.75  ? 544  THR   A CA    1 
ATOM   2518  C  C     . THR   C 3 251 ? 50.878  73.422  -0.067  1.00 32.98  ? 544  THR   A C     1 
ATOM   2519  O  O     . THR   C 3 251 ? 51.275  73.554  -1.216  1.00 35.20  ? 544  THR   A O     1 
ATOM   2520  C  CB    . THR   C 3 251 ? 49.322  71.502  0.228   1.00 34.91  ? 544  THR   A CB    1 
ATOM   2521  O  OG1   . THR   C 3 251 ? 49.185  70.251  0.900   1.00 32.79  ? 544  THR   A OG1   1 
ATOM   2522  C  CG2   . THR   C 3 251 ? 49.061  71.368  -1.260  1.00 35.66  ? 544  THR   A CG2   1 
ATOM   2523  N  N     . TYR   C 3 252 ? 50.622  74.464  0.741   1.00 34.09  ? 545  TYR   A N     1 
ATOM   2524  C  CA    . TYR   C 3 252 ? 50.570  75.827  0.222   1.00 36.80  ? 545  TYR   A CA    1 
ATOM   2525  C  C     . TYR   C 3 252 ? 51.563  76.767  0.907   1.00 35.78  ? 545  TYR   A C     1 
ATOM   2526  O  O     . TYR   C 3 252 ? 52.368  77.406  0.236   1.00 34.89  ? 545  TYR   A O     1 
ATOM   2527  C  CB    . TYR   C 3 252 ? 49.148  76.372  0.385   1.00 37.16  ? 545  TYR   A CB    1 
ATOM   2528  C  CG    . TYR   C 3 252 ? 48.119  75.528  -0.315  1.00 36.18  ? 545  TYR   A CG    1 
ATOM   2529  C  CD1   . TYR   C 3 252 ? 47.998  75.547  -1.701  1.00 34.27  ? 545  TYR   A CD1   1 
ATOM   2530  C  CD2   . TYR   C 3 252 ? 47.341  74.631  0.398   1.00 37.55  ? 545  TYR   A CD2   1 
ATOM   2531  C  CE1   . TYR   C 3 252 ? 47.079  74.741  -2.352  1.00 35.25  ? 545  TYR   A CE1   1 
ATOM   2532  C  CE2   . TYR   C 3 252 ? 46.427  73.807  -0.244  1.00 39.94  ? 545  TYR   A CE2   1 
ATOM   2533  C  CZ    . TYR   C 3 252 ? 46.296  73.868  -1.623  1.00 34.38  ? 545  TYR   A CZ    1 
ATOM   2534  O  OH    . TYR   C 3 252 ? 45.374  73.082  -2.241  1.00 38.06  ? 545  TYR   A OH    1 
ATOM   2535  N  N     . ILE   C 3 253 ? 51.465  76.891  2.233   1.00 41.55  ? 546  ILE   A N     1 
ATOM   2536  C  CA    . ILE   C 3 253 ? 52.122  77.968  2.971   1.00 42.62  ? 546  ILE   A CA    1 
ATOM   2537  C  C     . ILE   C 3 253 ? 53.646  77.857  2.853   1.00 40.40  ? 546  ILE   A C     1 
ATOM   2538  O  O     . ILE   C 3 253 ? 54.303  78.847  2.539   1.00 38.41  ? 546  ILE   A O     1 
ATOM   2539  C  CB    . ILE   C 3 253 ? 51.668  77.994  4.445   1.00 43.45  ? 546  ILE   A CB    1 
ATOM   2540  C  CG1   . ILE   C 3 253 ? 50.169  78.284  4.574   1.00 40.85  ? 546  ILE   A CG1   1 
ATOM   2541  C  CG2   . ILE   C 3 253 ? 52.500  79.001  5.223   1.00 44.20  ? 546  ILE   A CG2   1 
ATOM   2542  C  CD1   . ILE   C 3 253 ? 49.614  78.051  5.955   1.00 39.78  ? 546  ILE   A CD1   1 
ATOM   2543  N  N     . ASP   C 3 254 ? 54.203  76.655  3.060   1.00 40.83  ? 547  ASP   A N     1 
ATOM   2544  C  CA    . ASP   C 3 254 ? 55.653  76.477  3.027   1.00 41.75  ? 547  ASP   A CA    1 
ATOM   2545  C  C     . ASP   C 3 254 ? 56.188  76.360  1.598   1.00 40.24  ? 547  ASP   A C     1 
ATOM   2546  O  O     . ASP   C 3 254 ? 57.163  77.024  1.262   1.00 45.30  ? 547  ASP   A O     1 
ATOM   2547  C  CB    . ASP   C 3 254 ? 56.097  75.268  3.866   1.00 42.92  ? 547  ASP   A CB    1 
ATOM   2548  C  CG    . ASP   C 3 254 ? 55.875  75.420  5.361   1.00 42.89  ? 547  ASP   A CG    1 
ATOM   2549  O  OD1   . ASP   C 3 254 ? 55.814  76.575  5.850   1.00 44.84  ? 547  ASP   A OD1   1 
ATOM   2550  O  OD2   . ASP   C 3 254 ? 55.742  74.381  6.023   1.00 44.82  ? 547  ASP   A OD2   1 
ATOM   2551  N  N     . PRO   C 3 255 ? 55.659  75.459  0.733   1.00 39.58  ? 548  PRO   A N     1 
ATOM   2552  C  CA    . PRO   C 3 255 ? 56.214  75.260  -0.612  1.00 38.79  ? 548  PRO   A CA    1 
ATOM   2553  C  C     . PRO   C 3 255 ? 56.130  76.418  -1.602  1.00 38.91  ? 548  PRO   A C     1 
ATOM   2554  O  O     . PRO   C 3 255 ? 57.007  76.556  -2.446  1.00 44.71  ? 548  PRO   A O     1 
ATOM   2555  C  CB    . PRO   C 3 255 ? 55.360  74.140  -1.237  1.00 36.81  ? 548  PRO   A CB    1 
ATOM   2556  C  CG    . PRO   C 3 255 ? 54.679  73.471  -0.058  1.00 38.69  ? 548  PRO   A CG    1 
ATOM   2557  C  CD    . PRO   C 3 255 ? 54.551  74.530  1.018   1.00 38.34  ? 548  PRO   A CD    1 
ATOM   2558  N  N     . LEU   C 3 256 ? 55.038  77.192  -1.559  1.00 37.77  ? 549  LEU   A N     1 
ATOM   2559  C  CA    . LEU   C 3 256 ? 54.782  78.176  -2.603  1.00 38.87  ? 549  LEU   A CA    1 
ATOM   2560  C  C     . LEU   C 3 256 ? 55.848  79.272  -2.574  1.00 38.74  ? 549  LEU   A C     1 
ATOM   2561  O  O     . LEU   C 3 256 ? 56.361  79.654  -3.626  1.00 39.60  ? 549  LEU   A O     1 
ATOM   2562  C  CB    . LEU   C 3 256 ? 53.373  78.770  -2.448  1.00 39.28  ? 549  LEU   A CB    1 
ATOM   2563  C  CG    . LEU   C 3 256 ? 52.211  77.858  -2.850  1.00 40.53  ? 549  LEU   A CG    1 
ATOM   2564  C  CD1   . LEU   C 3 256 ? 50.889  78.522  -2.550  1.00 38.65  ? 549  LEU   A CD1   1 
ATOM   2565  C  CD2   . LEU   C 3 256 ? 52.280  77.456  -4.317  1.00 41.97  ? 549  LEU   A CD2   1 
ATOM   2566  N  N     . PRO   C 3 257 ? 56.191  79.857  -1.399  1.00 37.96  ? 550  PRO   A N     1 
ATOM   2567  C  CA    . PRO   C 3 257 ? 57.171  80.942  -1.370  1.00 38.85  ? 550  PRO   A CA    1 
ATOM   2568  C  C     . PRO   C 3 257 ? 58.574  80.498  -1.793  1.00 41.66  ? 550  PRO   A C     1 
ATOM   2569  O  O     . PRO   C 3 257 ? 59.367  81.324  -2.233  1.00 43.31  ? 550  PRO   A O     1 
ATOM   2570  C  CB    . PRO   C 3 257 ? 57.086  81.470  0.067   1.00 41.36  ? 550  PRO   A CB    1 
ATOM   2571  C  CG    . PRO   C 3 257 ? 56.479  80.342  0.891   1.00 42.43  ? 550  PRO   A CG    1 
ATOM   2572  C  CD    . PRO   C 3 257 ? 55.605  79.578  -0.074  1.00 41.04  ? 550  PRO   A CD    1 
ATOM   2573  N  N     . ASP   C 3 258 ? 58.832  79.185  -1.765  1.00 43.10  ? 551  ASP   A N     1 
ATOM   2574  C  CA    . ASP   C 3 258 ? 60.106  78.620  -2.185  1.00 47.67  ? 551  ASP   A CA    1 
ATOM   2575  C  C     . ASP   C 3 258 ? 60.167  78.418  -3.704  1.00 49.34  ? 551  ASP   A C     1 
ATOM   2576  O  O     . ASP   C 3 258 ? 61.216  78.032  -4.224  1.00 44.97  ? 551  ASP   A O     1 
ATOM   2577  C  CB    . ASP   C 3 258 ? 60.364  77.291  -1.457  1.00 49.11  ? 551  ASP   A CB    1 
ATOM   2578  C  CG    . ASP   C 3 258 ? 60.697  77.423  0.027   1.00 49.74  ? 551  ASP   A CG    1 
ATOM   2579  O  OD1   . ASP   C 3 258 ? 60.994  78.577  0.500   1.00 45.52  ? 551  ASP   A OD1   1 
ATOM   2580  O  OD2   . ASP   C 3 258 ? 60.650  76.377  0.702   1.00 45.10  ? 551  ASP   A OD2   1 
ATOM   2581  N  N     . LEU   C 3 259 ? 59.053  78.671  -4.407  1.00 47.63  ? 552  LEU   A N     1 
ATOM   2582  C  CA    . LEU   C 3 259 ? 58.948  78.426  -5.842  1.00 47.37  ? 552  LEU   A CA    1 
ATOM   2583  C  C     . LEU   C 3 259 ? 59.043  79.735  -6.625  1.00 38.60  ? 552  LEU   A C     1 
ATOM   2584  O  O     . LEU   C 3 259 ? 58.853  79.742  -7.841  1.00 41.03  ? 552  LEU   A O     1 
ATOM   2585  C  CB    . LEU   C 3 259 ? 57.619  77.706  -6.139  1.00 48.94  ? 552  LEU   A CB    1 
ATOM   2586  C  CG    . LEU   C 3 259 ? 57.596  76.195  -5.865  1.00 48.41  ? 552  LEU   A CG    1 
ATOM   2587  C  CD1   . LEU   C 3 259 ? 56.190  75.614  -6.046  1.00 44.77  ? 552  LEU   A CD1   1 
ATOM   2588  C  CD2   . LEU   C 3 259 ? 58.592  75.466  -6.762  1.00 44.28  ? 552  LEU   A CD2   1 
ATOM   2589  N  N     . ILE   C 3 260 ? 59.309  80.842  -5.926  1.00 40.15  ? 553  ILE   A N     1 
ATOM   2590  C  CA    . ILE   C 3 260 ? 59.533  82.119  -6.584  1.00 42.81  ? 553  ILE   A CA    1 
ATOM   2591  C  C     . ILE   C 3 260 ? 60.706  81.949  -7.549  1.00 42.19  ? 553  ILE   A C     1 
ATOM   2592  O  O     . ILE   C 3 260 ? 61.695  81.292  -7.224  1.00 45.61  ? 553  ILE   A O     1 
ATOM   2593  C  CB    . ILE   C 3 260 ? 59.775  83.249  -5.561  1.00 46.68  ? 553  ILE   A CB    1 
ATOM   2594  C  CG1   . ILE   C 3 260 ? 58.563  83.481  -4.655  1.00 49.63  ? 553  ILE   A CG1   1 
ATOM   2595  C  CG2   . ILE   C 3 260 ? 60.202  84.541  -6.250  1.00 49.09  ? 553  ILE   A CG2   1 
ATOM   2596  C  CD1   . ILE   C 3 260 ? 57.286  83.747  -5.403  1.00 51.77  ? 553  ILE   A CD1   1 
ATOM   2597  N  N     . HIS   C 3 261 ? 60.576  82.534  -8.743  1.00 37.36  ? 554  HIS   A N     1 
ATOM   2598  C  CA    . HIS   C 3 261 ? 61.450  82.188  -9.843  1.00 37.26  ? 554  HIS   A CA    1 
ATOM   2599  C  C     . HIS   C 3 261 ? 62.469  83.306  -10.061 1.00 41.56  ? 554  HIS   A C     1 
ATOM   2600  O  O     . HIS   C 3 261 ? 62.109  84.490  -10.069 1.00 41.50  ? 554  HIS   A O     1 
ATOM   2601  C  CB    . HIS   C 3 261 ? 60.617  81.908  -11.098 1.00 33.94  ? 554  HIS   A CB    1 
ATOM   2602  C  CG    . HIS   C 3 261 ? 61.401  81.347  -12.241 1.00 34.99  ? 554  HIS   A CG    1 
ATOM   2603  N  ND1   . HIS   C 3 261 ? 62.300  82.072  -12.973 1.00 39.94  ? 554  HIS   A ND1   1 
ATOM   2604  C  CD2   . HIS   C 3 261 ? 61.397  80.096  -12.771 1.00 39.55  ? 554  HIS   A CD2   1 
ATOM   2605  C  CE1   . HIS   C 3 261 ? 62.817  81.310  -13.935 1.00 39.36  ? 554  HIS   A CE1   1 
ATOM   2606  N  NE2   . HIS   C 3 261 ? 62.275  80.079  -13.826 1.00 39.69  ? 554  HIS   A NE2   1 
ATOM   2607  N  N     . PRO   C 3 262 ? 63.770  82.953  -10.205 1.00 45.09  ? 555  PRO   A N     1 
ATOM   2608  C  CA    . PRO   C 3 262 ? 64.845  83.937  -10.377 1.00 46.50  ? 555  PRO   A CA    1 
ATOM   2609  C  C     . PRO   C 3 262 ? 64.713  84.924  -11.537 1.00 50.18  ? 555  PRO   A C     1 
ATOM   2610  O  O     . PRO   C 3 262 ? 65.172  86.055  -11.438 1.00 50.22  ? 555  PRO   A O     1 
ATOM   2611  C  CB    . PRO   C 3 262 ? 66.102  83.087  -10.618 1.00 47.36  ? 555  PRO   A CB    1 
ATOM   2612  C  CG    . PRO   C 3 262 ? 65.597  81.682  -10.883 1.00 44.97  ? 555  PRO   A CG    1 
ATOM   2613  C  CD    . PRO   C 3 262 ? 64.283  81.572  -10.148 1.00 43.50  ? 555  PRO   A CD    1 
ATOM   2614  N  N     . ARG   C 3 263 ? 64.081  84.520  -12.639 1.00 48.69  ? 556  ARG   A N     1 
ATOM   2615  C  CA    . ARG   C 3 263 ? 64.033  85.387  -13.804 1.00 47.98  ? 556  ARG   A CA    1 
ATOM   2616  C  C     . ARG   C 3 263 ? 62.895  86.402  -13.729 1.00 43.52  ? 556  ARG   A C     1 
ATOM   2617  O  O     . ARG   C 3 263 ? 62.911  87.392  -14.465 1.00 37.54  ? 556  ARG   A O     1 
ATOM   2618  C  CB    . ARG   C 3 263 ? 63.880  84.543  -15.064 1.00 58.01  ? 556  ARG   A CB    1 
ATOM   2619  C  CG    . ARG   C 3 263 ? 65.083  83.649  -15.303 1.00 66.65  ? 556  ARG   A CG    1 
ATOM   2620  C  CD    . ARG   C 3 263 ? 66.160  84.271  -16.157 1.00 58.88  ? 556  ARG   A CD    1 
ATOM   2621  N  NE    . ARG   C 3 263 ? 66.723  83.107  -16.809 1.00 69.47  ? 556  ARG   A NE    1 
ATOM   2622  C  CZ    . ARG   C 3 263 ? 66.301  82.582  -17.958 1.00 78.86  ? 556  ARG   A CZ    1 
ATOM   2623  N  NH1   . ARG   C 3 263 ? 66.286  81.267  -18.111 1.00 78.32  ? 556  ARG   A NH1   1 
ATOM   2624  N  NH2   . ARG   C 3 263 ? 65.852  83.360  -18.933 1.00 86.39  ? 556  ARG   A NH2   1 
ATOM   2625  N  N     . THR   C 3 264 ? 61.890  86.139  -12.882 1.00 36.85  ? 557  THR   A N     1 
ATOM   2626  C  CA    . THR   C 3 264 ? 60.685  86.962  -12.876 1.00 38.16  ? 557  THR   A CA    1 
ATOM   2627  C  C     . THR   C 3 264 ? 60.385  87.542  -11.496 1.00 37.24  ? 557  THR   A C     1 
ATOM   2628  O  O     . THR   C 3 264 ? 59.707  88.560  -11.403 1.00 40.47  ? 557  THR   A O     1 
ATOM   2629  C  CB    . THR   C 3 264 ? 59.474  86.147  -13.341 1.00 37.52  ? 557  THR   A CB    1 
ATOM   2630  O  OG1   . THR   C 3 264 ? 59.247  85.115  -12.373 1.00 33.99  ? 557  THR   A OG1   1 
ATOM   2631  C  CG2   . THR   C 3 264 ? 59.684  85.559  -14.725 1.00 35.87  ? 557  THR   A CG2   1 
ATOM   2632  N  N     . GLY   C 3 265 ? 60.830  86.842  -10.443 1.00 38.80  ? 558  GLY   A N     1 
ATOM   2633  C  CA    . GLY   C 3 265 ? 60.439  87.141  -9.076  1.00 41.63  ? 558  GLY   A CA    1 
ATOM   2634  C  C     . GLY   C 3 265 ? 58.990  86.759  -8.789  1.00 40.97  ? 558  GLY   A C     1 
ATOM   2635  O  O     . GLY   C 3 265 ? 58.380  87.321  -7.882  1.00 42.29  ? 558  GLY   A O     1 
ATOM   2636  N  N     . ARG   C 3 266 ? 58.465  85.781  -9.547  1.00 43.14  ? 559  ARG   A N     1 
ATOM   2637  C  CA    . ARG   C 3 266 ? 57.060  85.391  -9.459  1.00 43.05  ? 559  ARG   A CA    1 
ATOM   2638  C  C     . ARG   C 3 266 ? 56.924  83.866  -9.384  1.00 42.65  ? 559  ARG   A C     1 
ATOM   2639  O  O     . ARG   C 3 266 ? 57.879  83.108  -9.599  1.00 36.58  ? 559  ARG   A O     1 
ATOM   2640  C  CB    . ARG   C 3 266 ? 56.285  86.016  -10.629 1.00 43.21  ? 559  ARG   A CB    1 
ATOM   2641  C  CG    . ARG   C 3 266 ? 56.163  87.534  -10.514 1.00 41.55  ? 559  ARG   A CG    1 
ATOM   2642  C  CD    . ARG   C 3 266 ? 55.794  88.309  -11.767 1.00 42.93  ? 559  ARG   A CD    1 
ATOM   2643  N  NE    . ARG   C 3 266 ? 54.403  88.155  -12.176 1.00 44.04  ? 559  ARG   A NE    1 
ATOM   2644  C  CZ    . ARG   C 3 266 ? 53.440  89.069  -12.077 1.00 42.56  ? 559  ARG   A CZ    1 
ATOM   2645  N  NH1   . ARG   C 3 266 ? 53.622  90.184  -11.399 1.00 37.57  ? 559  ARG   A NH1   1 
ATOM   2646  N  NH2   . ARG   C 3 266 ? 52.260  88.831  -12.626 1.00 45.75  ? 559  ARG   A NH2   1 
ATOM   2647  N  N     . LEU   C 3 267 ? 55.697  83.453  -9.044  1.00 39.58  ? 560  LEU   A N     1 
ATOM   2648  C  CA    . LEU   C 3 267 ? 55.287  82.061  -8.979  1.00 35.56  ? 560  LEU   A CA    1 
ATOM   2649  C  C     . LEU   C 3 267 ? 54.630  81.655  -10.300 1.00 35.38  ? 560  LEU   A C     1 
ATOM   2650  O  O     . LEU   C 3 267 ? 53.705  82.331  -10.768 1.00 33.97  ? 560  LEU   A O     1 
ATOM   2651  C  CB    . LEU   C 3 267 ? 54.313  81.938  -7.805  1.00 37.38  ? 560  LEU   A CB    1 
ATOM   2652  C  CG    . LEU   C 3 267 ? 53.711  80.554  -7.584  1.00 36.96  ? 560  LEU   A CG    1 
ATOM   2653  C  CD1   . LEU   C 3 267 ? 54.812  79.551  -7.327  1.00 40.12  ? 560  LEU   A CD1   1 
ATOM   2654  C  CD2   . LEU   C 3 267 ? 52.730  80.566  -6.428  1.00 37.84  ? 560  LEU   A CD2   1 
ATOM   2655  N  N     . HIS   C 3 268 ? 55.106  80.538  -10.878 1.00 35.16  ? 561  HIS   A N     1 
ATOM   2656  C  CA    . HIS   C 3 268 ? 54.644  80.051  -12.167 1.00 35.83  ? 561  HIS   A CA    1 
ATOM   2657  C  C     . HIS   C 3 268 ? 54.001  78.670  -12.026 1.00 41.26  ? 561  HIS   A C     1 
ATOM   2658  O  O     . HIS   C 3 268 ? 54.471  77.834  -11.256 1.00 53.23  ? 561  HIS   A O     1 
ATOM   2659  C  CB    . HIS   C 3 268 ? 55.775  80.029  -13.191 1.00 34.93  ? 561  HIS   A CB    1 
ATOM   2660  C  CG    . HIS   C 3 268 ? 56.387  81.372  -13.430 1.00 37.36  ? 561  HIS   A CG    1 
ATOM   2661  N  ND1   . HIS   C 3 268 ? 56.096  82.149  -14.507 1.00 38.62  ? 561  HIS   A ND1   1 
ATOM   2662  C  CD2   . HIS   C 3 268 ? 57.252  82.083  -12.650 1.00 40.39  ? 561  HIS   A CD2   1 
ATOM   2663  C  CE1   . HIS   C 3 268 ? 56.760  83.300  -14.412 1.00 39.00  ? 561  HIS   A CE1   1 
ATOM   2664  N  NE2   . HIS   C 3 268 ? 57.494  83.273  -13.277 1.00 40.65  ? 561  HIS   A NE2   1 
ATOM   2665  N  N     . THR   C 3 269 ? 52.903  78.472  -12.775 1.00 37.51  ? 562  THR   A N     1 
ATOM   2666  C  CA    . THR   C 3 269 ? 52.154  77.231  -12.803 1.00 35.19  ? 562  THR   A CA    1 
ATOM   2667  C  C     . THR   C 3 269 ? 52.124  76.759  -14.247 1.00 35.12  ? 562  THR   A C     1 
ATOM   2668  O  O     . THR   C 3 269 ? 52.578  77.475  -15.142 1.00 35.37  ? 562  THR   A O     1 
ATOM   2669  C  CB    . THR   C 3 269 ? 50.724  77.389  -12.259 1.00 35.52  ? 562  THR   A CB    1 
ATOM   2670  O  OG1   . THR   C 3 269 ? 50.122  76.103  -12.148 1.00 35.46  ? 562  THR   A OG1   1 
ATOM   2671  C  CG2   . THR   C 3 269 ? 49.838  78.237  -13.143 1.00 33.16  ? 562  THR   A CG2   1 
ATOM   2672  N  N     . ARG   C 3 270 ? 51.586  75.552  -14.438 1.00 35.44  ? 563  ARG   A N     1 
ATOM   2673  C  CA    . ARG   C 3 270 ? 51.285  75.010  -15.752 1.00 34.82  ? 563  ARG   A CA    1 
ATOM   2674  C  C     . ARG   C 3 270 ? 49.769  74.880  -15.886 1.00 34.30  ? 563  ARG   A C     1 
ATOM   2675  O  O     . ARG   C 3 270 ? 49.103  74.510  -14.925 1.00 36.75  ? 563  ARG   A O     1 
ATOM   2676  C  CB    . ARG   C 3 270 ? 51.989  73.669  -15.893 1.00 37.45  ? 563  ARG   A CB    1 
ATOM   2677  C  CG    . ARG   C 3 270 ? 53.442  73.745  -15.456 1.00 40.00  ? 563  ARG   A CG    1 
ATOM   2678  C  CD    . ARG   C 3 270 ? 54.173  72.427  -15.533 1.00 39.73  ? 563  ARG   A CD    1 
ATOM   2679  N  NE    . ARG   C 3 270 ? 54.131  71.809  -16.851 1.00 42.13  ? 563  ARG   A NE    1 
ATOM   2680  C  CZ    . ARG   C 3 270 ? 54.041  70.492  -17.038 1.00 41.72  ? 563  ARG   A CZ    1 
ATOM   2681  N  NH1   . ARG   C 3 270 ? 53.909  69.686  -15.997 1.00 44.35  ? 563  ARG   A NH1   1 
ATOM   2682  N  NH2   . ARG   C 3 270 ? 54.108  69.993  -18.257 1.00 42.90  ? 563  ARG   A NH2   1 
ATOM   2683  N  N     . PHE   C 3 271 ? 49.253  75.289  -17.051 1.00 34.23  ? 564  PHE   A N     1 
ATOM   2684  C  CA    . PHE   C 3 271 ? 47.874  75.094  -17.451 1.00 32.41  ? 564  PHE   A CA    1 
ATOM   2685  C  C     . PHE   C 3 271 ? 47.860  73.967  -18.468 1.00 29.49  ? 564  PHE   A C     1 
ATOM   2686  O  O     . PHE   C 3 271 ? 48.255  74.178  -19.605 1.00 29.28  ? 564  PHE   A O     1 
ATOM   2687  C  CB    . PHE   C 3 271 ? 47.296  76.408  -17.990 1.00 31.09  ? 564  PHE   A CB    1 
ATOM   2688  C  CG    . PHE   C 3 271 ? 47.035  77.400  -16.892 1.00 31.48  ? 564  PHE   A CG    1 
ATOM   2689  C  CD1   . PHE   C 3 271 ? 46.045  77.149  -15.953 1.00 31.64  ? 564  PHE   A CD1   1 
ATOM   2690  C  CD2   . PHE   C 3 271 ? 47.840  78.524  -16.739 1.00 30.77  ? 564  PHE   A CD2   1 
ATOM   2691  C  CE1   . PHE   C 3 271 ? 45.824  78.041  -14.916 1.00 35.03  ? 564  PHE   A CE1   1 
ATOM   2692  C  CE2   . PHE   C 3 271 ? 47.629  79.404  -15.694 1.00 29.95  ? 564  PHE   A CE2   1 
ATOM   2693  C  CZ    . PHE   C 3 271 ? 46.622  79.163  -14.783 1.00 33.64  ? 564  PHE   A CZ    1 
ATOM   2694  N  N     . ASN   C 3 272 ? 47.461  72.779  -18.017 1.00 28.80  ? 565  ASN   A N     1 
ATOM   2695  C  CA    . ASN   C 3 272 ? 47.476  71.580  -18.839 1.00 28.09  ? 565  ASN   A CA    1 
ATOM   2696  C  C     . ASN   C 3 272 ? 46.227  71.587  -19.717 1.00 29.28  ? 565  ASN   A C     1 
ATOM   2697  O  O     . ASN   C 3 272 ? 45.112  71.705  -19.215 1.00 23.21  ? 565  ASN   A O     1 
ATOM   2698  C  CB    . ASN   C 3 272 ? 47.585  70.332  -17.969 1.00 27.22  ? 565  ASN   A CB    1 
ATOM   2699  C  CG    . ASN   C 3 272 ? 48.708  70.453  -16.960 1.00 29.56  ? 565  ASN   A CG    1 
ATOM   2700  O  OD1   . ASN   C 3 272 ? 49.866  70.649  -17.338 1.00 30.76  ? 565  ASN   A OD1   1 
ATOM   2701  N  ND2   . ASN   C 3 272 ? 48.365  70.406  -15.681 1.00 25.06  ? 565  ASN   A ND2   1 
ATOM   2702  N  N     . GLN   C 3 273 ? 46.429  71.505  -21.042 1.00 30.11  ? 566  GLN   A N     1 
ATOM   2703  C  CA    . GLN   C 3 273 ? 45.340  71.762  -21.970 1.00 28.73  ? 566  GLN   A CA    1 
ATOM   2704  C  C     . GLN   C 3 273 ? 44.704  70.465  -22.472 1.00 30.49  ? 566  GLN   A C     1 
ATOM   2705  O  O     . GLN   C 3 273 ? 43.704  70.548  -23.174 1.00 30.96  ? 566  GLN   A O     1 
ATOM   2706  C  CB    . GLN   C 3 273 ? 45.839  72.615  -23.140 1.00 28.04  ? 566  GLN   A CB    1 
ATOM   2707  C  CG    . GLN   C 3 273 ? 44.729  73.122  -24.040 1.00 26.56  ? 566  GLN   A CG    1 
ATOM   2708  C  CD    . GLN   C 3 273 ? 45.227  74.108  -25.061 1.00 29.12  ? 566  GLN   A CD    1 
ATOM   2709  O  OE1   . GLN   C 3 273 ? 46.422  74.429  -25.120 1.00 32.37  ? 566  GLN   A OE1   1 
ATOM   2710  N  NE2   . GLN   C 3 273 ? 44.312  74.573  -25.900 1.00 25.75  ? 566  GLN   A NE2   1 
ATOM   2711  N  N     . THR   C 3 274 ? 45.282  69.285  -22.156 1.00 30.03  ? 567  THR   A N     1 
ATOM   2712  C  CA    . THR   C 3 274 ? 44.733  68.000  -22.582 1.00 26.93  ? 567  THR   A CA    1 
ATOM   2713  C  C     . THR   C 3 274 ? 44.798  67.001  -21.434 1.00 28.07  ? 567  THR   A C     1 
ATOM   2714  O  O     . THR   C 3 274 ? 45.371  65.924  -21.587 1.00 31.92  ? 567  THR   A O     1 
ATOM   2715  C  CB    . THR   C 3 274 ? 45.471  67.425  -23.803 1.00 27.75  ? 567  THR   A CB    1 
ATOM   2716  O  OG1   . THR   C 3 274 ? 46.797  67.015  -23.459 1.00 30.84  ? 567  THR   A OG1   1 
ATOM   2717  C  CG2   . THR   C 3 274 ? 45.579  68.410  -24.944 1.00 27.64  ? 567  THR   A CG2   1 
ATOM   2718  N  N     . ALA   C 3 275 ? 44.176  67.344  -20.303 1.00 26.91  ? 568  ALA   A N     1 
ATOM   2719  C  CA    . ALA   C 3 275 ? 44.341  66.577  -19.078 1.00 28.97  ? 568  ALA   A CA    1 
ATOM   2720  C  C     . ALA   C 3 275 ? 43.017  66.072  -18.490 1.00 31.55  ? 568  ALA   A C     1 
ATOM   2721  O  O     . ALA   C 3 275 ? 43.058  65.233  -17.588 1.00 39.20  ? 568  ALA   A O     1 
ATOM   2722  C  CB    . ALA   C 3 275 ? 45.090  67.419  -18.062 1.00 27.17  ? 568  ALA   A CB    1 
ATOM   2723  N  N     . THR   C 3 276 ? 41.854  66.552  -18.972 1.00 33.39  ? 569  THR   A N     1 
ATOM   2724  C  CA    . THR   C 3 276 ? 40.563  66.222  -18.365 1.00 30.05  ? 569  THR   A CA    1 
ATOM   2725  C  C     . THR   C 3 276 ? 39.607  65.579  -19.371 1.00 29.84  ? 569  THR   A C     1 
ATOM   2726  O  O     . THR   C 3 276 ? 39.740  65.784  -20.575 1.00 30.34  ? 569  THR   A O     1 
ATOM   2727  C  CB    . THR   C 3 276 ? 39.908  67.463  -17.738 1.00 30.58  ? 569  THR   A CB    1 
ATOM   2728  O  OG1   . THR   C 3 276 ? 39.419  68.312  -18.778 1.00 29.14  ? 569  THR   A OG1   1 
ATOM   2729  C  CG2   . THR   C 3 276 ? 40.859  68.209  -16.825 1.00 29.41  ? 569  THR   A CG2   1 
ATOM   2730  N  N     . ALA   C 3 277 ? 38.606  64.844  -18.855 1.00 31.70  ? 570  ALA   A N     1 
ATOM   2731  C  CA    . ALA   C 3 277 ? 37.648  64.121  -19.687 1.00 32.49  ? 570  ALA   A CA    1 
ATOM   2732  C  C     . ALA   C 3 277 ? 36.499  65.018  -20.147 1.00 29.71  ? 570  ALA   A C     1 
ATOM   2733  O  O     . ALA   C 3 277 ? 35.664  64.606  -20.951 1.00 29.92  ? 570  ALA   A O     1 
ATOM   2734  C  CB    . ALA   C 3 277 ? 37.100  62.946  -18.917 1.00 34.35  ? 570  ALA   A CB    1 
ATOM   2735  N  N     . THR   C 3 278 ? 36.439  66.241  -19.625 1.00 30.93  ? 571  THR   A N     1 
ATOM   2736  C  CA    . THR   C 3 278 ? 35.304  67.114  -19.868 1.00 29.48  ? 571  THR   A CA    1 
ATOM   2737  C  C     . THR   C 3 278 ? 35.648  68.321  -20.732 1.00 27.78  ? 571  THR   A C     1 
ATOM   2738  O  O     . THR   C 3 278 ? 34.734  69.012  -21.175 1.00 30.11  ? 571  THR   A O     1 
ATOM   2739  C  CB    . THR   C 3 278 ? 34.747  67.622  -18.542 1.00 30.58  ? 571  THR   A CB    1 
ATOM   2740  O  OG1   . THR   C 3 278 ? 35.835  68.259  -17.848 1.00 29.99  ? 571  THR   A OG1   1 
ATOM   2741  C  CG2   . THR   C 3 278 ? 34.093  66.488  -17.778 1.00 31.99  ? 571  THR   A CG2   1 
ATOM   2742  N  N     . GLY   C 3 279 ? 36.936  68.603  -20.955 1.00 27.54  ? 572  GLY   A N     1 
ATOM   2743  C  CA    . GLY   C 3 279 ? 37.310  69.818  -21.672 1.00 26.94  ? 572  GLY   A CA    1 
ATOM   2744  C  C     . GLY   C 3 279 ? 37.804  70.953  -20.773 1.00 26.37  ? 572  GLY   A C     1 
ATOM   2745  O  O     . GLY   C 3 279 ? 38.147  72.014  -21.267 1.00 27.89  ? 572  GLY   A O     1 
ATOM   2746  N  N     . ARG   C 3 280 ? 37.822  70.748  -19.452 1.00 30.54  ? 573  ARG   A N     1 
ATOM   2747  C  CA    . ARG   C 3 280 ? 38.434  71.704  -18.543 1.00 29.30  ? 573  ARG   A CA    1 
ATOM   2748  C  C     . ARG   C 3 280 ? 39.942  71.707  -18.737 1.00 28.33  ? 573  ARG   A C     1 
ATOM   2749  O  O     . ARG   C 3 280 ? 40.532  70.768  -19.294 1.00 28.29  ? 573  ARG   A O     1 
ATOM   2750  C  CB    . ARG   C 3 280 ? 38.178  71.413  -17.058 1.00 28.70  ? 573  ARG   A CB    1 
ATOM   2751  C  CG    . ARG   C 3 280 ? 36.762  71.701  -16.587 1.00 28.10  ? 573  ARG   A CG    1 
ATOM   2752  C  CD    . ARG   C 3 280 ? 36.747  72.283  -15.185 1.00 31.73  ? 573  ARG   A CD    1 
ATOM   2753  N  NE    . ARG   C 3 280 ? 35.505  71.975  -14.487 1.00 30.34  ? 573  ARG   A NE    1 
ATOM   2754  C  CZ    . ARG   C 3 280 ? 35.244  72.208  -13.202 1.00 29.53  ? 573  ARG   A CZ    1 
ATOM   2755  N  NH1   . ARG   C 3 280 ? 34.114  72.819  -12.858 1.00 28.79  ? 573  ARG   A NH1   1 
ATOM   2756  N  NH2   . ARG   C 3 280 ? 36.004  71.649  -12.276 1.00 29.82  ? 573  ARG   A NH2   1 
ATOM   2757  N  N     . LEU   C 3 281 ? 40.528  72.822  -18.297 1.00 26.69  ? 574  LEU   A N     1 
ATOM   2758  C  CA    . LEU   C 3 281 ? 41.956  72.890  -18.066 1.00 28.10  ? 574  LEU   A CA    1 
ATOM   2759  C  C     . LEU   C 3 281 ? 42.256  72.208  -16.741 1.00 26.96  ? 574  LEU   A C     1 
ATOM   2760  O  O     . LEU   C 3 281 ? 41.362  72.019  -15.924 1.00 26.43  ? 574  LEU   A O     1 
ATOM   2761  C  CB    . LEU   C 3 281 ? 42.390  74.351  -17.980 1.00 27.96  ? 574  LEU   A CB    1 
ATOM   2762  C  CG    . LEU   C 3 281 ? 42.171  75.204  -19.217 1.00 28.89  ? 574  LEU   A CG    1 
ATOM   2763  C  CD1   . LEU   C 3 281 ? 42.667  76.613  -18.940 1.00 31.43  ? 574  LEU   A CD1   1 
ATOM   2764  C  CD2   . LEU   C 3 281 ? 42.870  74.604  -20.430 1.00 30.73  ? 574  LEU   A CD2   1 
ATOM   2765  N  N     . SER   C 3 282 ? 43.523  71.841  -16.541 1.00 30.00  ? 575  SER   A N     1 
ATOM   2766  C  CA    . SER   C 3 282 ? 44.011  71.536  -15.205 1.00 31.77  ? 575  SER   A CA    1 
ATOM   2767  C  C     . SER   C 3 282 ? 45.217  72.431  -14.958 1.00 30.63  ? 575  SER   A C     1 
ATOM   2768  O  O     . SER   C 3 282 ? 45.652  73.139  -15.863 1.00 29.93  ? 575  SER   A O     1 
ATOM   2769  C  CB    . SER   C 3 282 ? 44.290  70.065  -15.002 1.00 32.19  ? 575  SER   A CB    1 
ATOM   2770  O  OG    . SER   C 3 282 ? 45.624  69.730  -15.349 1.00 34.24  ? 575  SER   A OG    1 
ATOM   2771  N  N     . SER   C 3 283 ? 45.652  72.497  -13.698 1.00 32.10  ? 576  SER   A N     1 
ATOM   2772  C  CA    . SER   C 3 283 ? 46.803  73.298  -13.312 1.00 30.28  ? 576  SER   A CA    1 
ATOM   2773  C  C     . SER   C 3 283 ? 47.676  72.433  -12.422 1.00 30.05  ? 576  SER   A C     1 
ATOM   2774  O  O     . SER   C 3 283 ? 47.150  71.683  -11.605 1.00 28.98  ? 576  SER   A O     1 
ATOM   2775  C  CB    . SER   C 3 283 ? 46.376  74.545  -12.604 1.00 32.36  ? 576  SER   A CB    1 
ATOM   2776  O  OG    . SER   C 3 283 ? 47.486  75.287  -12.137 1.00 35.25  ? 576  SER   A OG    1 
ATOM   2777  N  N     . SER   C 3 284 ? 48.991  72.518  -12.604 1.00 29.55  ? 577  SER   A N     1 
ATOM   2778  C  CA    . SER   C 3 284 ? 49.887  71.708  -11.801 1.00 30.93  ? 577  SER   A CA    1 
ATOM   2779  C  C     . SER   C 3 284 ? 51.235  72.409  -11.609 1.00 31.93  ? 577  SER   A C     1 
ATOM   2780  O  O     . SER   C 3 284 ? 51.552  73.354  -12.320 1.00 30.92  ? 577  SER   A O     1 
ATOM   2781  C  CB    . SER   C 3 284 ? 50.014  70.316  -12.398 1.00 31.64  ? 577  SER   A CB    1 
ATOM   2782  O  OG    . SER   C 3 284 ? 50.696  70.318  -13.638 1.00 30.84  ? 577  SER   A OG    1 
ATOM   2783  N  N     . ASP   C 3 285 ? 51.978  71.992  -10.568 1.00 38.03  ? 578  ASP   A N     1 
ATOM   2784  C  CA    . ASP   C 3 285 ? 53.399  72.305  -10.421 1.00 34.80  ? 578  ASP   A CA    1 
ATOM   2785  C  C     . ASP   C 3 285 ? 53.636  73.798  -10.192 1.00 31.88  ? 578  ASP   A C     1 
ATOM   2786  O  O     . ASP   C 3 285 ? 54.436  74.407  -10.905 1.00 34.00  ? 578  ASP   A O     1 
ATOM   2787  C  CB    . ASP   C 3 285 ? 54.165  71.797  -11.651 1.00 35.93  ? 578  ASP   A CB    1 
ATOM   2788  C  CG    . ASP   C 3 285 ? 53.954  70.313  -11.913 1.00 37.48  ? 578  ASP   A CG    1 
ATOM   2789  O  OD1   . ASP   C 3 285 ? 54.267  69.531  -11.013 1.00 37.60  ? 578  ASP   A OD1   1 
ATOM   2790  O  OD2   . ASP   C 3 285 ? 53.460  69.956  -13.003 1.00 47.13  ? 578  ASP   A OD2   1 
ATOM   2791  N  N     . PRO   C 3 286 ? 52.957  74.481  -9.234  1.00 32.85  ? 579  PRO   A N     1 
ATOM   2792  C  CA    . PRO   C 3 286 ? 51.893  73.924  -8.399  1.00 32.22  ? 579  PRO   A CA    1 
ATOM   2793  C  C     . PRO   C 3 286 ? 50.488  74.129  -8.960  1.00 29.79  ? 579  PRO   A C     1 
ATOM   2794  O  O     . PRO   C 3 286 ? 50.328  74.805  -9.971  1.00 32.52  ? 579  PRO   A O     1 
ATOM   2795  C  CB    . PRO   C 3 286 ? 52.062  74.785  -7.141  1.00 31.94  ? 579  PRO   A CB    1 
ATOM   2796  C  CG    . PRO   C 3 286 ? 52.286  76.150  -7.711  1.00 32.91  ? 579  PRO   A CG    1 
ATOM   2797  C  CD    . PRO   C 3 286 ? 53.183  75.904  -8.908  1.00 33.99  ? 579  PRO   A CD    1 
ATOM   2798  N  N     . ASN   C 3 287 ? 49.483  73.564  -8.279  1.00 27.93  ? 580  ASN   A N     1 
ATOM   2799  C  CA    . ASN   C 3 287 ? 48.106  73.658  -8.731  1.00 27.06  ? 580  ASN   A CA    1 
ATOM   2800  C  C     . ASN   C 3 287 ? 47.506  74.963  -8.229  1.00 26.67  ? 580  ASN   A C     1 
ATOM   2801  O  O     . ASN   C 3 287 ? 46.942  74.996  -7.136  1.00 30.11  ? 580  ASN   A O     1 
ATOM   2802  C  CB    . ASN   C 3 287 ? 47.261  72.455  -8.287  1.00 28.17  ? 580  ASN   A CB    1 
ATOM   2803  C  CG    . ASN   C 3 287 ? 45.836  72.510  -8.813  1.00 28.79  ? 580  ASN   A CG    1 
ATOM   2804  O  OD1   . ASN   C 3 287 ? 45.461  73.482  -9.464  1.00 29.01  ? 580  ASN   A OD1   1 
ATOM   2805  N  ND2   . ASN   C 3 287 ? 45.026  71.500  -8.524  1.00 27.38  ? 580  ASN   A ND2   1 
ATOM   2806  N  N     . LEU   C 3 288 ? 47.547  76.007  -9.065  1.00 26.67  ? 581  LEU   A N     1 
ATOM   2807  C  CA    . LEU   C 3 288 ? 46.991  77.311  -8.703  1.00 26.84  ? 581  LEU   A CA    1 
ATOM   2808  C  C     . LEU   C 3 288 ? 45.484  77.399  -8.967  1.00 29.33  ? 581  LEU   A C     1 
ATOM   2809  O  O     . LEU   C 3 288 ? 44.914  78.500  -8.901  1.00 28.47  ? 581  LEU   A O     1 
ATOM   2810  C  CB    . LEU   C 3 288 ? 47.750  78.417  -9.445  1.00 26.52  ? 581  LEU   A CB    1 
ATOM   2811  C  CG    . LEU   C 3 288 ? 49.217  78.592  -9.005  1.00 27.38  ? 581  LEU   A CG    1 
ATOM   2812  C  CD1   . LEU   C 3 288 ? 49.838  79.862  -9.568  1.00 26.63  ? 581  LEU   A CD1   1 
ATOM   2813  C  CD2   . LEU   C 3 288 ? 49.327  78.584  -7.490  1.00 27.84  ? 581  LEU   A CD2   1 
ATOM   2814  N  N     . GLN   C 3 289 ? 44.845  76.236  -9.200  1.00 27.73  ? 582  GLN   A N     1 
ATOM   2815  C  CA    . GLN   C 3 289 ? 43.393  76.148  -9.254  1.00 29.99  ? 582  GLN   A CA    1 
ATOM   2816  C  C     . GLN   C 3 289 ? 42.861  75.517  -7.964  1.00 28.51  ? 582  GLN   A C     1 
ATOM   2817  O  O     . GLN   C 3 289 ? 41.693  75.145  -7.924  1.00 27.39  ? 582  GLN   A O     1 
ATOM   2818  C  CB    . GLN   C 3 289 ? 42.883  75.358  -10.482 1.00 27.08  ? 582  GLN   A CB    1 
ATOM   2819  C  CG    . GLN   C 3 289 ? 43.248  75.958  -11.836 1.00 26.85  ? 582  GLN   A CG    1 
ATOM   2820  C  CD    . GLN   C 3 289 ? 42.733  75.176  -13.028 1.00 28.37  ? 582  GLN   A CD    1 
ATOM   2821  O  OE1   . GLN   C 3 289 ? 42.652  73.944  -13.006 1.00 23.94  ? 582  GLN   A OE1   1 
ATOM   2822  N  NE2   . GLN   C 3 289 ? 42.340  75.900  -14.072 1.00 25.92  ? 582  GLN   A NE2   1 
ATOM   2823  N  N     . SER   C 3 290 ? 43.716  75.390  -6.936  1.00 30.80  ? 583  SER   A N     1 
ATOM   2824  C  CA    . SER   C 3 290 ? 43.347  74.716  -5.697  1.00 32.58  ? 583  SER   A CA    1 
ATOM   2825  C  C     . SER   C 3 290 ? 43.708  75.549  -4.467  1.00 33.22  ? 583  SER   A C     1 
ATOM   2826  O  O     . SER   C 3 290 ? 43.744  75.013  -3.359  1.00 34.74  ? 583  SER   A O     1 
ATOM   2827  C  CB    . SER   C 3 290 ? 44.001  73.358  -5.594  1.00 34.98  ? 583  SER   A CB    1 
ATOM   2828  O  OG    . SER   C 3 290 ? 45.402  73.512  -5.375  1.00 37.13  ? 583  SER   A OG    1 
ATOM   2829  N  N     . ILE   C 3 291 ? 43.953  76.852  -4.650  1.00 32.27  ? 584  ILE   A N     1 
ATOM   2830  C  CA    . ILE   C 3 291 ? 44.360  77.701  -3.539  1.00 32.91  ? 584  ILE   A CA    1 
ATOM   2831  C  C     . ILE   C 3 291 ? 43.206  77.836  -2.542  1.00 34.73  ? 584  ILE   A C     1 
ATOM   2832  O  O     . ILE   C 3 291 ? 42.098  78.194  -2.926  1.00 35.26  ? 584  ILE   A O     1 
ATOM   2833  C  CB    . ILE   C 3 291 ? 44.825  79.082  -4.028  1.00 32.26  ? 584  ILE   A CB    1 
ATOM   2834  C  CG1   . ILE   C 3 291 ? 45.995  78.992  -5.020  1.00 29.65  ? 584  ILE   A CG1   1 
ATOM   2835  C  CG2   . ILE   C 3 291 ? 45.137  79.980  -2.840  1.00 32.97  ? 584  ILE   A CG2   1 
ATOM   2836  C  CD1   . ILE   C 3 291 ? 47.089  78.072  -4.612  1.00 29.04  ? 584  ILE   A CD1   1 
ATOM   2837  N  N     . PRO   C 3 292 ? 43.431  77.579  -1.229  1.00 34.22  ? 585  PRO   A N     1 
ATOM   2838  C  CA    . PRO   C 3 292 ? 42.371  77.682  -0.226  1.00 32.10  ? 585  PRO   A CA    1 
ATOM   2839  C  C     . PRO   C 3 292 ? 41.662  79.021  -0.259  1.00 32.91  ? 585  PRO   A C     1 
ATOM   2840  O  O     . PRO   C 3 292 ? 42.271  80.026  -0.630  1.00 30.64  ? 585  PRO   A O     1 
ATOM   2841  C  CB    . PRO   C 3 292 ? 43.113  77.472  1.092   1.00 34.13  ? 585  PRO   A CB    1 
ATOM   2842  C  CG    . PRO   C 3 292 ? 44.239  76.539  0.692   1.00 34.32  ? 585  PRO   A CG    1 
ATOM   2843  C  CD    . PRO   C 3 292 ? 44.688  77.066  -0.655  1.00 34.16  ? 585  PRO   A CD    1 
ATOM   2844  N  N     . VAL   C 3 293 ? 40.364  78.987  0.092   1.00 35.32  ? 586  VAL   A N     1 
ATOM   2845  C  CA    . VAL   C 3 293 ? 39.501  80.155  0.009   1.00 37.60  ? 586  VAL   A CA    1 
ATOM   2846  C  C     . VAL   C 3 293 ? 38.405  80.125  1.074   1.00 40.07  ? 586  VAL   A C     1 
ATOM   2847  O  O     . VAL   C 3 293 ? 37.849  81.151  1.445   1.00 46.34  ? 586  VAL   A O     1 
ATOM   2848  C  CB    . VAL   C 3 293 ? 38.870  80.238  -1.394  1.00 34.02  ? 586  VAL   A CB    1 
ATOM   2849  C  CG1   . VAL   C 3 293 ? 37.922  79.083  -1.666  1.00 33.30  ? 586  VAL   A CG1   1 
ATOM   2850  C  CG2   . VAL   C 3 293 ? 38.164  81.562  -1.602  1.00 33.42  ? 586  VAL   A CG2   1 
ATOM   2851  N  N     . ARG   C 3 294 ? 38.077  78.928  1.528   1.00 43.33  ? 587  ARG   A N     1 
ATOM   2852  C  CA    . ARG   C 3 294 ? 36.805  78.624  2.155   1.00 48.41  ? 587  ARG   A CA    1 
ATOM   2853  C  C     . ARG   C 3 294 ? 36.827  78.967  3.652   1.00 53.42  ? 587  ARG   A C     1 
ATOM   2854  O  O     . ARG   C 3 294 ? 35.941  79.656  4.141   1.00 56.47  ? 587  ARG   A O     1 
ATOM   2855  C  CB    . ARG   C 3 294 ? 36.586  77.130  1.908   1.00 49.05  ? 587  ARG   A CB    1 
ATOM   2856  C  CG    . ARG   C 3 294 ? 35.320  76.536  2.494   1.00 52.15  ? 587  ARG   A CG    1 
ATOM   2857  C  CD    . ARG   C 3 294 ? 35.266  75.055  2.163   1.00 54.78  ? 587  ARG   A CD    1 
ATOM   2858  N  NE    . ARG   C 3 294 ? 35.611  74.189  3.287   1.00 58.58  ? 587  ARG   A NE    1 
ATOM   2859  C  CZ    . ARG   C 3 294 ? 36.674  73.395  3.323   1.00 66.62  ? 587  ARG   A CZ    1 
ATOM   2860  N  NH1   . ARG   C 3 294 ? 37.786  73.758  2.715   1.00 61.33  ? 587  ARG   A NH1   1 
ATOM   2861  N  NH2   . ARG   C 3 294 ? 36.639  72.256  4.000   1.00 70.55  ? 587  ARG   A NH2   1 
ATOM   2862  N  N     . THR   C 3 295 ? 37.826  78.432  4.379   1.00 50.39  ? 588  THR   A N     1 
ATOM   2863  C  CA    . THR   C 3 295 ? 37.950  78.589  5.819   1.00 43.48  ? 588  THR   A CA    1 
ATOM   2864  C  C     . THR   C 3 295 ? 38.684  79.881  6.149   1.00 42.92  ? 588  THR   A C     1 
ATOM   2865  O  O     . THR   C 3 295 ? 39.362  80.457  5.302   1.00 43.44  ? 588  THR   A O     1 
ATOM   2866  C  CB    . THR   C 3 295 ? 38.726  77.431  6.465   1.00 38.45  ? 588  THR   A CB    1 
ATOM   2867  O  OG1   . THR   C 3 295 ? 40.077  77.509  6.001   1.00 37.01  ? 588  THR   A OG1   1 
ATOM   2868  C  CG2   . THR   C 3 295 ? 38.112  76.080  6.184   1.00 37.90  ? 588  THR   A CG2   1 
ATOM   2869  N  N     . PRO   C 3 296 ? 38.575  80.360  7.408   1.00 45.88  ? 589  PRO   A N     1 
ATOM   2870  C  CA    . PRO   C 3 296 ? 39.326  81.533  7.856   1.00 45.11  ? 589  PRO   A CA    1 
ATOM   2871  C  C     . PRO   C 3 296 ? 40.816  81.524  7.521   1.00 42.08  ? 589  PRO   A C     1 
ATOM   2872  O  O     . PRO   C 3 296 ? 41.342  82.541  7.057   1.00 42.01  ? 589  PRO   A O     1 
ATOM   2873  C  CB    . PRO   C 3 296 ? 39.026  81.529  9.365   1.00 47.17  ? 589  PRO   A CB    1 
ATOM   2874  C  CG    . PRO   C 3 296 ? 37.587  81.040  9.416   1.00 47.00  ? 589  PRO   A CG    1 
ATOM   2875  C  CD    . PRO   C 3 296 ? 37.617  79.888  8.432   1.00 48.95  ? 589  PRO   A CD    1 
ATOM   2876  N  N     . LEU   C 3 297 ? 41.494  80.390  7.743   1.00 41.60  ? 590  LEU   A N     1 
ATOM   2877  C  CA    . LEU   C 3 297 ? 42.905  80.288  7.389   1.00 40.88  ? 590  LEU   A CA    1 
ATOM   2878  C  C     . LEU   C 3 297 ? 43.085  80.303  5.866   1.00 42.37  ? 590  LEU   A C     1 
ATOM   2879  O  O     . LEU   C 3 297 ? 44.083  80.828  5.347   1.00 38.41  ? 590  LEU   A O     1 
ATOM   2880  C  CB    . LEU   C 3 297 ? 43.495  79.007  7.986   1.00 45.79  ? 590  LEU   A CB    1 
ATOM   2881  C  CG    . LEU   C 3 297 ? 44.961  78.748  7.619   1.00 49.36  ? 590  LEU   A CG    1 
ATOM   2882  C  CD1   . LEU   C 3 297 ? 45.834  79.896  8.084   1.00 51.15  ? 590  LEU   A CD1   1 
ATOM   2883  C  CD2   . LEU   C 3 297 ? 45.471  77.440  8.212   1.00 54.91  ? 590  LEU   A CD2   1 
ATOM   2884  N  N     . GLY   C 3 298 ? 42.126  79.683  5.155   1.00 39.74  ? 591  GLY   A N     1 
ATOM   2885  C  CA    . GLY   C 3 298 ? 42.170  79.647  3.712   1.00 37.50  ? 591  GLY   A CA    1 
ATOM   2886  C  C     . GLY   C 3 298 ? 42.176  81.051  3.134   1.00 33.87  ? 591  GLY   A C     1 
ATOM   2887  O  O     . GLY   C 3 298 ? 42.895  81.329  2.173   1.00 37.65  ? 591  GLY   A O     1 
ATOM   2888  N  N     . GLN   C 3 299 ? 41.392  81.939  3.747   1.00 36.98  ? 592  GLN   A N     1 
ATOM   2889  C  CA    . GLN   C 3 299 ? 41.262  83.311  3.263   1.00 41.20  ? 592  GLN   A CA    1 
ATOM   2890  C  C     . GLN   C 3 299 ? 42.579  84.068  3.432   1.00 44.42  ? 592  GLN   A C     1 
ATOM   2891  O  O     . GLN   C 3 299 ? 42.900  84.974  2.663   1.00 49.19  ? 592  GLN   A O     1 
ATOM   2892  C  CB    . GLN   C 3 299 ? 40.087  83.993  3.966   1.00 43.91  ? 592  GLN   A CB    1 
ATOM   2893  C  CG    . GLN   C 3 299 ? 38.739  83.429  3.518   1.00 52.39  ? 592  GLN   A CG    1 
ATOM   2894  C  CD    . GLN   C 3 299 ? 37.584  83.812  4.412   1.00 62.67  ? 592  GLN   A CD    1 
ATOM   2895  O  OE1   . GLN   C 3 299 ? 37.730  84.589  5.354   1.00 75.58  ? 592  GLN   A OE1   1 
ATOM   2896  N  NE2   . GLN   C 3 299 ? 36.417  83.247  4.136   1.00 65.76  ? 592  GLN   A NE2   1 
ATOM   2897  N  N     . ARG   C 3 300 ? 43.367  83.682  4.433   1.00 45.77  ? 593  ARG   A N     1 
ATOM   2898  C  CA    . ARG   C 3 300 ? 44.624  84.366  4.694   1.00 47.87  ? 593  ARG   A CA    1 
ATOM   2899  C  C     . ARG   C 3 300 ? 45.661  83.974  3.639   1.00 42.27  ? 593  ARG   A C     1 
ATOM   2900  O  O     . ARG   C 3 300 ? 46.522  84.771  3.292   1.00 41.18  ? 593  ARG   A O     1 
ATOM   2901  C  CB    . ARG   C 3 300 ? 45.024  84.082  6.144   1.00 53.65  ? 593  ARG   A CB    1 
ATOM   2902  C  CG    . ARG   C 3 300 ? 43.944  84.516  7.130   1.00 60.55  ? 593  ARG   A CG    1 
ATOM   2903  C  CD    . ARG   C 3 300 ? 44.322  84.259  8.568   1.00 63.75  ? 593  ARG   A CD    1 
ATOM   2904  N  NE    . ARG   C 3 300 ? 45.555  84.975  8.865   1.00 64.36  ? 593  ARG   A NE    1 
ATOM   2905  C  CZ    . ARG   C 3 300 ? 46.319  84.721  9.914   1.00 57.58  ? 593  ARG   A CZ    1 
ATOM   2906  N  NH1   . ARG   C 3 300 ? 45.904  83.836  10.802  1.00 51.57  ? 593  ARG   A NH1   1 
ATOM   2907  N  NH2   . ARG   C 3 300 ? 47.480  85.340  10.051  1.00 51.70  ? 593  ARG   A NH2   1 
ATOM   2908  N  N     . ILE   C 3 301 ? 45.557  82.760  3.090   1.00 41.80  ? 594  ILE   A N     1 
ATOM   2909  C  CA    . ILE   C 3 301 ? 46.451  82.322  2.024   1.00 38.46  ? 594  ILE   A CA    1 
ATOM   2910  C  C     . ILE   C 3 301 ? 46.180  83.137  0.748   1.00 38.20  ? 594  ILE   A C     1 
ATOM   2911  O  O     . ILE   C 3 301 ? 47.124  83.579  0.092   1.00 39.42  ? 594  ILE   A O     1 
ATOM   2912  C  CB    . ILE   C 3 301 ? 46.348  80.790  1.835   1.00 35.78  ? 594  ILE   A CB    1 
ATOM   2913  C  CG1   . ILE   C 3 301 ? 46.741  80.075  3.130   1.00 34.74  ? 594  ILE   A CG1   1 
ATOM   2914  C  CG2   . ILE   C 3 301 ? 47.182  80.309  0.648   1.00 36.52  ? 594  ILE   A CG2   1 
ATOM   2915  C  CD1   . ILE   C 3 301 ? 46.803  78.572  3.038   1.00 33.70  ? 594  ILE   A CD1   1 
ATOM   2916  N  N     . ARG   C 3 302 ? 44.902  83.385  0.414   1.00 38.74  ? 595  ARG   A N     1 
ATOM   2917  C  CA    . ARG   C 3 302 ? 44.564  84.185  -0.761  1.00 39.77  ? 595  ARG   A CA    1 
ATOM   2918  C  C     . ARG   C 3 302 ? 45.133  85.592  -0.656  1.00 40.62  ? 595  ARG   A C     1 
ATOM   2919  O  O     . ARG   C 3 302 ? 45.378  86.229  -1.676  1.00 43.61  ? 595  ARG   A O     1 
ATOM   2920  C  CB    . ARG   C 3 302 ? 43.053  84.372  -0.944  1.00 42.92  ? 595  ARG   A CB    1 
ATOM   2921  C  CG    . ARG   C 3 302 ? 42.293  83.128  -1.373  1.00 43.58  ? 595  ARG   A CG    1 
ATOM   2922  C  CD    . ARG   C 3 302 ? 42.633  82.745  -2.797  1.00 41.80  ? 595  ARG   A CD    1 
ATOM   2923  N  NE    . ARG   C 3 302 ? 42.002  81.482  -3.146  1.00 42.74  ? 595  ARG   A NE    1 
ATOM   2924  C  CZ    . ARG   C 3 302 ? 41.095  81.330  -4.099  1.00 39.39  ? 595  ARG   A CZ    1 
ATOM   2925  N  NH1   . ARG   C 3 302 ? 40.716  80.106  -4.430  1.00 37.78  ? 595  ARG   A NH1   1 
ATOM   2926  N  NH2   . ARG   C 3 302 ? 40.557  82.394  -4.674  1.00 39.10  ? 595  ARG   A NH2   1 
ATOM   2927  N  N     . ARG   C 3 303 ? 45.287  86.082  0.578   1.00 41.39  ? 596  ARG   A N     1 
ATOM   2928  C  CA    . ARG   C 3 303 ? 45.844  87.403  0.830   1.00 45.55  ? 596  ARG   A CA    1 
ATOM   2929  C  C     . ARG   C 3 303 ? 47.288  87.480  0.323   1.00 42.74  ? 596  ARG   A C     1 
ATOM   2930  O  O     . ARG   C 3 303 ? 47.798  88.563  0.048   1.00 42.32  ? 596  ARG   A O     1 
ATOM   2931  C  CB    . ARG   C 3 303 ? 45.803  87.675  2.334   1.00 55.80  ? 596  ARG   A CB    1 
ATOM   2932  C  CG    . ARG   C 3 303 ? 45.593  89.125  2.734   1.00 67.18  ? 596  ARG   A CG    1 
ATOM   2933  C  CD    . ARG   C 3 303 ? 45.228  89.180  4.208   1.00 78.56  ? 596  ARG   A CD    1 
ATOM   2934  N  NE    . ARG   C 3 303 ? 44.289  90.256  4.480   1.00 88.83  ? 596  ARG   A NE    1 
ATOM   2935  C  CZ    . ARG   C 3 303 ? 43.115  90.100  5.102   1.00 97.94  ? 596  ARG   A CZ    1 
ATOM   2936  N  NH1   . ARG   C 3 303 ? 42.821  88.944  5.676   1.00 98.09  ? 596  ARG   A NH1   1 
ATOM   2937  N  NH2   . ARG   C 3 303 ? 42.244  91.112  5.154   1.00 108.42 ? 596  ARG   A NH2   1 
ATOM   2938  N  N     . ALA   C 3 304 ? 47.950  86.321  0.226   1.00 39.85  ? 597  ALA   A N     1 
ATOM   2939  C  CA    . ALA   C 3 304 ? 49.353  86.251  -0.155  1.00 39.47  ? 597  ALA   A CA    1 
ATOM   2940  C  C     . ALA   C 3 304 ? 49.535  86.391  -1.665  1.00 38.28  ? 597  ALA   A C     1 
ATOM   2941  O  O     . ALA   C 3 304 ? 50.654  86.560  -2.117  1.00 38.22  ? 597  ALA   A O     1 
ATOM   2942  C  CB    . ALA   C 3 304 ? 49.946  84.951  0.322   1.00 42.56  ? 597  ALA   A CB    1 
ATOM   2943  N  N     . PHE   C 3 305 ? 48.454  86.287  -2.443  1.00 36.98  ? 598  PHE   A N     1 
ATOM   2944  C  CA    . PHE   C 3 305 ? 48.534  86.468  -3.884  1.00 32.98  ? 598  PHE   A CA    1 
ATOM   2945  C  C     . PHE   C 3 305 ? 48.246  87.934  -4.206  1.00 33.94  ? 598  PHE   A C     1 
ATOM   2946  O  O     . PHE   C 3 305 ? 47.118  88.387  -4.030  1.00 33.45  ? 598  PHE   A O     1 
ATOM   2947  C  CB    . PHE   C 3 305 ? 47.561  85.495  -4.559  1.00 31.10  ? 598  PHE   A CB    1 
ATOM   2948  C  CG    . PHE   C 3 305 ? 48.012  84.057  -4.515  1.00 29.90  ? 598  PHE   A CG    1 
ATOM   2949  C  CD1   . PHE   C 3 305 ? 47.886  83.306  -3.361  1.00 29.40  ? 598  PHE   A CD1   1 
ATOM   2950  C  CD2   . PHE   C 3 305 ? 48.636  83.481  -5.609  1.00 29.24  ? 598  PHE   A CD2   1 
ATOM   2951  C  CE1   . PHE   C 3 305 ? 48.339  81.999  -3.304  1.00 28.81  ? 598  PHE   A CE1   1 
ATOM   2952  C  CE2   . PHE   C 3 305 ? 49.081  82.174  -5.556  1.00 29.42  ? 598  PHE   A CE2   1 
ATOM   2953  C  CZ    . PHE   C 3 305 ? 48.929  81.433  -4.405  1.00 29.45  ? 598  PHE   A CZ    1 
ATOM   2954  N  N     . ILE   C 3 306 ? 49.273  88.661  -4.664  1.00 33.68  ? 599  ILE   A N     1 
ATOM   2955  C  CA    . ILE   C 3 306 ? 49.252  90.113  -4.727  1.00 36.07  ? 599  ILE   A CA    1 
ATOM   2956  C  C     . ILE   C 3 306 ? 49.631  90.557  -6.135  1.00 36.80  ? 599  ILE   A C     1 
ATOM   2957  O  O     . ILE   C 3 306 ? 50.103  89.746  -6.932  1.00 39.14  ? 599  ILE   A O     1 
ATOM   2958  C  CB    . ILE   C 3 306 ? 50.191  90.756  -3.678  1.00 38.02  ? 599  ILE   A CB    1 
ATOM   2959  C  CG1   . ILE   C 3 306 ? 51.642  90.281  -3.810  1.00 40.77  ? 599  ILE   A CG1   1 
ATOM   2960  C  CG2   . ILE   C 3 306 ? 49.654  90.544  -2.276  1.00 38.91  ? 599  ILE   A CG2   1 
ATOM   2961  C  CD1   . ILE   C 3 306 ? 52.660  91.155  -3.085  1.00 40.64  ? 599  ILE   A CD1   1 
ATOM   2962  N  N     . ALA   C 3 307 ? 49.404  91.853  -6.418  1.00 35.94  ? 600  ALA   A N     1 
ATOM   2963  C  CA    . ALA   C 3 307 ? 49.783  92.453  -7.689  1.00 35.32  ? 600  ALA   A CA    1 
ATOM   2964  C  C     . ALA   C 3 307 ? 51.179  93.055  -7.597  1.00 35.00  ? 600  ALA   A C     1 
ATOM   2965  O  O     . ALA   C 3 307 ? 51.664  93.339  -6.509  1.00 38.46  ? 600  ALA   A O     1 
ATOM   2966  C  CB    . ALA   C 3 307 ? 48.780  93.494  -8.081  1.00 35.51  ? 600  ALA   A CB    1 
ATOM   2967  N  N     . GLU   C 3 308 ? 51.824  93.194  -8.758  1.00 42.08  ? 601  GLU   A N     1 
ATOM   2968  C  CA    . GLU   C 3 308 ? 53.034  93.979  -8.912  1.00 48.67  ? 601  GLU   A CA    1 
ATOM   2969  C  C     . GLU   C 3 308 ? 52.775  95.388  -8.372  1.00 56.42  ? 601  GLU   A C     1 
ATOM   2970  O  O     . GLU   C 3 308 ? 51.628  95.831  -8.284  1.00 54.33  ? 601  GLU   A O     1 
ATOM   2971  C  CB    . GLU   C 3 308 ? 53.450  93.983  -10.384 1.00 47.87  ? 601  GLU   A CB    1 
ATOM   2972  C  CG    . GLU   C 3 308 ? 54.739  94.724  -10.661 1.00 47.64  ? 601  GLU   A CG    1 
ATOM   2973  C  CD    . GLU   C 3 308 ? 55.129  94.744  -12.125 1.00 53.09  ? 601  GLU   A CD    1 
ATOM   2974  O  OE1   . GLU   C 3 308 ? 55.039  93.672  -12.777 1.00 57.58  ? 601  GLU   A OE1   1 
ATOM   2975  O  OE2   . GLU   C 3 308 ? 55.556  95.815  -12.602 1.00 53.23  ? 601  GLU   A OE2   1 
ATOM   2976  N  N     . GLU   C 3 309 ? 53.851  96.066  -7.949  1.00 61.07  ? 602  GLU   A N     1 
ATOM   2977  C  CA    . GLU   C 3 309 ? 53.741  97.408  -7.400  1.00 63.37  ? 602  GLU   A CA    1 
ATOM   2978  C  C     . GLU   C 3 309 ? 53.262  98.329  -8.512  1.00 51.41  ? 602  GLU   A C     1 
ATOM   2979  O  O     . GLU   C 3 309 ? 53.855  98.365  -9.587  1.00 53.08  ? 602  GLU   A O     1 
ATOM   2980  C  CB    . GLU   C 3 309 ? 55.073  97.860  -6.791  1.00 75.04  ? 602  GLU   A CB    1 
ATOM   2981  C  CG    . GLU   C 3 309 ? 55.197  97.534  -5.301  1.00 85.31  ? 602  GLU   A CG    1 
ATOM   2982  C  CD    . GLU   C 3 309 ? 54.420  98.483  -4.392  1.00 90.60  ? 602  GLU   A CD    1 
ATOM   2983  O  OE1   . GLU   C 3 309 ? 54.616  99.715  -4.520  1.00 83.06  ? 602  GLU   A OE1   1 
ATOM   2984  O  OE2   . GLU   C 3 309 ? 53.619  98.000  -3.553  1.00 89.21  ? 602  GLU   A OE2   1 
ATOM   2985  N  N     . GLY   C 3 310 ? 52.173  99.045  -8.228  1.00 47.94  ? 603  GLY   A N     1 
ATOM   2986  C  CA    . GLY   C 3 310 ? 51.563  99.947  -9.186  1.00 49.47  ? 603  GLY   A CA    1 
ATOM   2987  C  C     . GLY   C 3 310 ? 50.398  99.304  -9.938  1.00 52.47  ? 603  GLY   A C     1 
ATOM   2988  O  O     . GLY   C 3 310 ? 49.781  99.975  -10.766 1.00 52.46  ? 603  GLY   A O     1 
ATOM   2989  N  N     . TRP   C 3 311 ? 50.115  98.016  -9.647  1.00 48.00  ? 604  TRP   A N     1 
ATOM   2990  C  CA    . TRP   C 3 311 ? 49.088  97.256  -10.353 1.00 45.67  ? 604  TRP   A CA    1 
ATOM   2991  C  C     . TRP   C 3 311 ? 48.012  96.794  -9.377  1.00 44.17  ? 604  TRP   A C     1 
ATOM   2992  O  O     . TRP   C 3 311 ? 48.194  96.823  -8.154  1.00 48.46  ? 604  TRP   A O     1 
ATOM   2993  C  CB    . TRP   C 3 311 ? 49.670  96.050  -11.111 1.00 43.54  ? 604  TRP   A CB    1 
ATOM   2994  C  CG    . TRP   C 3 311 ? 50.647  96.367  -12.200 1.00 41.35  ? 604  TRP   A CG    1 
ATOM   2995  C  CD1   . TRP   C 3 311 ? 51.783  97.107  -12.081 1.00 43.13  ? 604  TRP   A CD1   1 
ATOM   2996  C  CD2   . TRP   C 3 311 ? 50.616  95.908  -13.564 1.00 45.13  ? 604  TRP   A CD2   1 
ATOM   2997  N  NE1   . TRP   C 3 311 ? 52.448  97.160  -13.275 1.00 44.45  ? 604  TRP   A NE1   1 
ATOM   2998  C  CE2   . TRP   C 3 311 ? 51.762  96.440  -14.207 1.00 44.75  ? 604  TRP   A CE2   1 
ATOM   2999  C  CE3   . TRP   C 3 311 ? 49.739  95.109  -14.313 1.00 42.34  ? 604  TRP   A CE3   1 
ATOM   3000  C  CZ2   . TRP   C 3 311 ? 52.047  96.215  -15.558 1.00 43.69  ? 604  TRP   A CZ2   1 
ATOM   3001  C  CZ3   . TRP   C 3 311 ? 50.018  94.883  -15.645 1.00 42.60  ? 604  TRP   A CZ3   1 
ATOM   3002  C  CH2   . TRP   C 3 311 ? 51.162  95.420  -16.256 1.00 46.03  ? 604  TRP   A CH2   1 
ATOM   3003  N  N     . LEU   C 3 312 ? 46.897  96.339  -9.954  1.00 43.41  ? 605  LEU   A N     1 
ATOM   3004  C  CA    . LEU   C 3 312 ? 45.824  95.702  -9.204  1.00 44.24  ? 605  LEU   A CA    1 
ATOM   3005  C  C     . LEU   C 3 312 ? 45.432  94.387  -9.887  1.00 42.46  ? 605  LEU   A C     1 
ATOM   3006  O  O     . LEU   C 3 312 ? 45.562  94.242  -11.104 1.00 42.32  ? 605  LEU   A O     1 
ATOM   3007  C  CB    . LEU   C 3 312 ? 44.632  96.665  -9.130  1.00 45.80  ? 605  LEU   A CB    1 
ATOM   3008  C  CG    . LEU   C 3 312 ? 44.807  97.927  -8.277  1.00 47.91  ? 605  LEU   A CG    1 
ATOM   3009  C  CD1   . LEU   C 3 312 ? 43.572  98.810  -8.373  1.00 48.81  ? 605  LEU   A CD1   1 
ATOM   3010  C  CD2   . LEU   C 3 312 ? 45.069  97.577  -6.813  1.00 46.42  ? 605  LEU   A CD2   1 
ATOM   3011  N  N     . LEU   C 3 313 ? 44.963  93.436  -9.071  1.00 37.88  ? 606  LEU   A N     1 
ATOM   3012  C  CA    . LEU   C 3 313 ? 44.314  92.226  -9.539  1.00 38.57  ? 606  LEU   A CA    1 
ATOM   3013  C  C     . LEU   C 3 313 ? 42.855  92.529  -9.874  1.00 37.85  ? 606  LEU   A C     1 
ATOM   3014  O  O     . LEU   C 3 313 ? 42.188  93.236  -9.118  1.00 38.52  ? 606  LEU   A O     1 
ATOM   3015  C  CB    . LEU   C 3 313 ? 44.382  91.146  -8.447  1.00 35.10  ? 606  LEU   A CB    1 
ATOM   3016  C  CG    . LEU   C 3 313 ? 45.775  90.632  -8.094  1.00 35.73  ? 606  LEU   A CG    1 
ATOM   3017  C  CD1   . LEU   C 3 313 ? 45.680  89.378  -7.247  1.00 39.52  ? 606  LEU   A CD1   1 
ATOM   3018  C  CD2   . LEU   C 3 313 ? 46.621  90.366  -9.327  1.00 36.88  ? 606  LEU   A CD2   1 
ATOM   3019  N  N     . VAL   C 3 314 ? 42.373  91.944  -10.986 1.00 37.09  ? 607  VAL   A N     1 
ATOM   3020  C  CA    . VAL   C 3 314 ? 40.957  91.928  -11.333 1.00 36.34  ? 607  VAL   A CA    1 
ATOM   3021  C  C     . VAL   C 3 314 ? 40.490  90.477  -11.380 1.00 33.80  ? 607  VAL   A C     1 
ATOM   3022  O  O     . VAL   C 3 314 ? 40.995  89.695  -12.174 1.00 37.12  ? 607  VAL   A O     1 
ATOM   3023  C  CB    . VAL   C 3 314 ? 40.708  92.647  -12.674 1.00 38.31  ? 607  VAL   A CB    1 
ATOM   3024  C  CG1   . VAL   C 3 314 ? 39.228  92.885  -12.919 1.00 41.85  ? 607  VAL   A CG1   1 
ATOM   3025  C  CG2   . VAL   C 3 314 ? 41.476  93.961  -12.761 1.00 38.17  ? 607  VAL   A CG2   1 
ATOM   3026  N  N     . ALA   C 3 315 ? 39.534  90.121  -10.522 1.00 34.07  ? 608  ALA   A N     1 
ATOM   3027  C  CA    . ALA   C 3 315 ? 38.979  88.780  -10.472 1.00 36.54  ? 608  ALA   A CA    1 
ATOM   3028  C  C     . ALA   C 3 315 ? 37.536  88.778  -10.987 1.00 39.55  ? 608  ALA   A C     1 
ATOM   3029  O  O     . ALA   C 3 315 ? 36.709  89.507  -10.450 1.00 36.44  ? 608  ALA   A O     1 
ATOM   3030  C  CB    . ALA   C 3 315 ? 39.026  88.283  -9.053  1.00 36.87  ? 608  ALA   A CB    1 
ATOM   3031  N  N     . LEU   C 3 316 ? 37.247  87.906  -11.972 1.00 37.60  ? 609  LEU   A N     1 
ATOM   3032  C  CA    . LEU   C 3 316 ? 35.927  87.747  -12.564 1.00 36.04  ? 609  LEU   A CA    1 
ATOM   3033  C  C     . LEU   C 3 316 ? 35.525  86.275  -12.511 1.00 37.81  ? 609  LEU   A C     1 
ATOM   3034  O  O     . LEU   C 3 316 ? 36.237  85.441  -13.067 1.00 36.87  ? 609  LEU   A O     1 
ATOM   3035  C  CB    . LEU   C 3 316 ? 35.968  88.223  -14.020 1.00 37.54  ? 609  LEU   A CB    1 
ATOM   3036  C  CG    . LEU   C 3 316 ? 36.636  89.570  -14.275 1.00 37.99  ? 609  LEU   A CG    1 
ATOM   3037  C  CD1   . LEU   C 3 316 ? 38.029  89.392  -14.888 1.00 38.24  ? 609  LEU   A CD1   1 
ATOM   3038  C  CD2   . LEU   C 3 316 ? 35.762  90.441  -15.158 1.00 37.11  ? 609  LEU   A CD2   1 
ATOM   3039  N  N     . ASP   C 3 317 ? 34.374  85.982  -11.882 1.00 38.02  ? 610  ASP   A N     1 
ATOM   3040  C  CA    . ASP   C 3 317 ? 33.900  84.625  -11.607 1.00 43.89  ? 610  ASP   A CA    1 
ATOM   3041  C  C     . ASP   C 3 317 ? 32.464  84.516  -12.117 1.00 43.84  ? 610  ASP   A C     1 
ATOM   3042  O  O     . ASP   C 3 317 ? 31.601  85.227  -11.610 1.00 48.86  ? 610  ASP   A O     1 
ATOM   3043  C  CB    . ASP   C 3 317 ? 33.950  84.302  -10.098 1.00 43.54  ? 610  ASP   A CB    1 
ATOM   3044  C  CG    . ASP   C 3 317 ? 33.623  82.869  -9.650  1.00 49.92  ? 610  ASP   A CG    1 
ATOM   3045  O  OD1   . ASP   C 3 317 ? 32.538  82.264  -10.064 1.00 46.83  ? 610  ASP   A OD1   1 
ATOM   3046  O  OD2   . ASP   C 3 317 ? 34.416  82.336  -8.833  1.00 48.21  ? 610  ASP   A OD2   1 
ATOM   3047  N  N     . TYR   C 3 318 ? 32.196  83.635  -13.104 1.00 41.31  ? 611  TYR   A N     1 
ATOM   3048  C  CA    . TYR   C 3 318 ? 30.822  83.349  -13.508 1.00 35.69  ? 611  TYR   A CA    1 
ATOM   3049  C  C     . TYR   C 3 318 ? 29.980  82.906  -12.295 1.00 37.66  ? 611  TYR   A C     1 
ATOM   3050  O  O     . TYR   C 3 318 ? 30.329  81.983  -11.466 1.00 41.95  ? 611  TYR   A O     1 
ATOM   3051  C  CB    . TYR   C 3 318 ? 30.753  82.350  -14.661 1.00 35.57  ? 611  TYR   A CB    1 
ATOM   3052  C  CG    . TYR   C 3 318 ? 31.208  82.823  -16.026 1.00 34.48  ? 611  TYR   A CG    1 
ATOM   3053  C  CD1   . TYR   C 3 318 ? 30.483  83.735  -16.775 1.00 35.64  ? 611  TYR   A CD1   1 
ATOM   3054  C  CD2   . TYR   C 3 318 ? 32.337  82.289  -16.627 1.00 34.87  ? 611  TYR   A CD2   1 
ATOM   3055  C  CE1   . TYR   C 3 318 ? 30.888  84.139  -18.050 1.00 33.50  ? 611  TYR   A CE1   1 
ATOM   3056  C  CE2   . TYR   C 3 318 ? 32.744  82.673  -17.899 1.00 34.96  ? 611  TYR   A CE2   1 
ATOM   3057  C  CZ    . TYR   C 3 318 ? 32.022  83.598  -18.626 1.00 31.63  ? 611  TYR   A CZ    1 
ATOM   3058  O  OH    . TYR   C 3 318 ? 32.462  83.942  -19.904 1.00 33.15  ? 611  TYR   A OH    1 
ATOM   3059  N  N     . SER   C 3 319 ? 28.881  83.676  -12.154 1.00 38.28  ? 612  SER   A N     1 
ATOM   3060  C  CA    . SER   C 3 319 ? 27.878  83.444  -11.125 1.00 40.29  ? 612  SER   A CA    1 
ATOM   3061  C  C     . SER   C 3 319 ? 27.052  82.219  -11.506 1.00 39.33  ? 612  SER   A C     1 
ATOM   3062  O  O     . SER   C 3 319 ? 26.556  82.157  -12.628 1.00 43.68  ? 612  SER   A O     1 
ATOM   3063  C  CB    . SER   C 3 319 ? 27.008  84.666  -10.899 1.00 43.05  ? 612  SER   A CB    1 
ATOM   3064  O  OG    . SER   C 3 319 ? 25.755  84.309  -10.290 1.00 50.14  ? 612  SER   A OG    1 
ATOM   3065  N  N     . GLN   C 3 320 ? 26.938  81.278  -10.553 1.00 40.25  ? 613  GLN   A N     1 
ATOM   3066  C  CA    . GLN   C 3 320 ? 26.190  80.037  -10.661 1.00 39.53  ? 613  GLN   A CA    1 
ATOM   3067  C  C     . GLN   C 3 320 ? 26.323  79.474  -12.072 1.00 39.82  ? 613  GLN   A C     1 
ATOM   3068  O  O     . GLN   C 3 320 ? 25.338  79.004  -12.630 1.00 40.76  ? 613  GLN   A O     1 
ATOM   3069  C  CB    . GLN   C 3 320 ? 24.713  80.253  -10.289 1.00 44.14  ? 613  GLN   A CB    1 
ATOM   3070  C  CG    . GLN   C 3 320 ? 24.436  80.746  -8.867  1.00 42.95  ? 613  GLN   A CG    1 
ATOM   3071  C  CD    . GLN   C 3 320 ? 22.979  81.128  -8.706  1.00 48.48  ? 613  GLN   A CD    1 
ATOM   3072  O  OE1   . GLN   C 3 320 ? 22.098  80.309  -8.401  1.00 47.52  ? 613  GLN   A OE1   1 
ATOM   3073  N  NE2   . GLN   C 3 320 ? 22.704  82.403  -8.941  1.00 42.49  ? 613  GLN   A NE2   1 
ATOM   3074  N  N     . GLU   C 3 321 ? 27.542  79.488  -12.619 1.00 39.08  ? 614  GLU   A N     1 
ATOM   3075  C  CA    . GLU   C 3 321 ? 27.773  79.261  -14.041 1.00 46.57  ? 614  GLU   A CA    1 
ATOM   3076  C  C     . GLU   C 3 321 ? 27.225  77.912  -14.524 1.00 45.53  ? 614  GLU   A C     1 
ATOM   3077  O  O     . GLU   C 3 321 ? 26.608  77.863  -15.594 1.00 41.09  ? 614  GLU   A O     1 
ATOM   3078  C  CB    . GLU   C 3 321 ? 29.246  79.557  -14.361 1.00 58.05  ? 614  GLU   A CB    1 
ATOM   3079  C  CG    . GLU   C 3 321 ? 29.971  78.625  -15.321 1.00 63.15  ? 614  GLU   A CG    1 
ATOM   3080  C  CD    . GLU   C 3 321 ? 30.766  77.562  -14.571 1.00 77.21  ? 614  GLU   A CD    1 
ATOM   3081  O  OE1   . GLU   C 3 321 ? 30.537  77.436  -13.337 1.00 72.44  ? 614  GLU   A OE1   1 
ATOM   3082  O  OE2   . GLU   C 3 321 ? 31.649  76.900  -15.191 1.00 78.17  ? 614  GLU   A OE2   1 
ATOM   3083  N  N     . GLY   C 3 322 ? 27.424  76.834  -13.757 1.00 40.47  ? 615  GLY   A N     1 
ATOM   3084  C  CA    . GLY   C 3 322 ? 27.043  75.510  -14.219 1.00 41.25  ? 615  GLY   A CA    1 
ATOM   3085  C  C     . GLY   C 3 322 ? 25.536  75.328  -14.297 1.00 39.46  ? 615  GLY   A C     1 
ATOM   3086  O  O     . GLY   C 3 322 ? 25.035  74.588  -15.142 1.00 40.32  ? 615  GLY   A O     1 
ATOM   3087  N  N     . LEU   C 3 323 ? 24.844  75.995  -13.366 1.00 42.35  ? 616  LEU   A N     1 
ATOM   3088  C  CA    . LEU   C 3 323 ? 23.395  76.007  -13.299 1.00 40.86  ? 616  LEU   A CA    1 
ATOM   3089  C  C     . LEU   C 3 323 ? 22.812  76.856  -14.431 1.00 35.59  ? 616  LEU   A C     1 
ATOM   3090  O  O     . LEU   C 3 323 ? 21.764  76.520  -14.942 1.00 32.75  ? 616  LEU   A O     1 
ATOM   3091  C  CB    . LEU   C 3 323 ? 22.966  76.542  -11.930 1.00 43.91  ? 616  LEU   A CB    1 
ATOM   3092  C  CG    . LEU   C 3 323 ? 23.403  75.725  -10.715 1.00 51.64  ? 616  LEU   A CG    1 
ATOM   3093  C  CD1   . LEU   C 3 323 ? 23.022  76.448  -9.419  1.00 55.23  ? 616  LEU   A CD1   1 
ATOM   3094  C  CD2   . LEU   C 3 323 ? 22.805  74.312  -10.740 1.00 51.47  ? 616  LEU   A CD2   1 
ATOM   3095  N  N     . ARG   C 3 324 ? 23.470  77.956  -14.816 1.00 36.01  ? 617  ARG   A N     1 
ATOM   3096  C  CA    . ARG   C 3 324 ? 23.039  78.728  -15.974 1.00 35.05  ? 617  ARG   A CA    1 
ATOM   3097  C  C     . ARG   C 3 324 ? 23.197  77.902  -17.245 1.00 33.50  ? 617  ARG   A C     1 
ATOM   3098  O  O     . ARG   C 3 324 ? 22.367  77.982  -18.137 1.00 36.89  ? 617  ARG   A O     1 
ATOM   3099  C  CB    . ARG   C 3 324 ? 23.818  80.032  -16.145 1.00 31.83  ? 617  ARG   A CB    1 
ATOM   3100  C  CG    . ARG   C 3 324 ? 23.557  81.026  -15.031 1.00 33.95  ? 617  ARG   A CG    1 
ATOM   3101  C  CD    . ARG   C 3 324 ? 24.149  82.399  -15.287 1.00 35.66  ? 617  ARG   A CD    1 
ATOM   3102  N  NE    . ARG   C 3 324 ? 24.106  83.204  -14.064 1.00 35.19  ? 617  ARG   A NE    1 
ATOM   3103  C  CZ    . ARG   C 3 324 ? 23.307  84.240  -13.850 1.00 32.52  ? 617  ARG   A CZ    1 
ATOM   3104  N  NH1   . ARG   C 3 324 ? 22.647  84.813  -14.843 1.00 29.79  ? 617  ARG   A NH1   1 
ATOM   3105  N  NH2   . ARG   C 3 324 ? 23.198  84.716  -12.627 1.00 34.46  ? 617  ARG   A NH2   1 
ATOM   3106  N  N     . VAL   C 3 325 ? 24.280  77.131  -17.329 1.00 34.69  ? 618  VAL   A N     1 
ATOM   3107  C  CA    . VAL   C 3 325 ? 24.534  76.300  -18.493 1.00 33.06  ? 618  VAL   A CA    1 
ATOM   3108  C  C     . VAL   C 3 325 ? 23.467  75.208  -18.581 1.00 31.30  ? 618  VAL   A C     1 
ATOM   3109  O  O     . VAL   C 3 325 ? 22.970  74.912  -19.661 1.00 30.83  ? 618  VAL   A O     1 
ATOM   3110  C  CB    . VAL   C 3 325 ? 25.966  75.744  -18.459 1.00 30.10  ? 618  VAL   A CB    1 
ATOM   3111  C  CG1   . VAL   C 3 325 ? 26.189  74.628  -19.453 1.00 29.47  ? 618  VAL   A CG1   1 
ATOM   3112  C  CG2   . VAL   C 3 325 ? 26.972  76.860  -18.707 1.00 33.68  ? 618  VAL   A CG2   1 
ATOM   3113  N  N     . LEU   C 3 326 ? 23.076  74.656  -17.436 1.00 28.68  ? 619  LEU   A N     1 
ATOM   3114  C  CA    . LEU   C 3 326 ? 22.058  73.632  -17.404 1.00 28.53  ? 619  LEU   A CA    1 
ATOM   3115  C  C     . LEU   C 3 326 ? 20.713  74.194  -17.850 1.00 28.49  ? 619  LEU   A C     1 
ATOM   3116  O  O     . LEU   C 3 326 ? 19.958  73.527  -18.552 1.00 32.91  ? 619  LEU   A O     1 
ATOM   3117  C  CB    . LEU   C 3 326 ? 21.959  73.108  -15.974 1.00 34.11  ? 619  LEU   A CB    1 
ATOM   3118  C  CG    . LEU   C 3 326 ? 20.850  72.091  -15.715 1.00 34.29  ? 619  LEU   A CG    1 
ATOM   3119  C  CD1   . LEU   C 3 326 ? 21.068  70.811  -16.520 1.00 36.18  ? 619  LEU   A CD1   1 
ATOM   3120  C  CD2   . LEU   C 3 326 ? 20.780  71.789  -14.226 1.00 39.63  ? 619  LEU   A CD2   1 
ATOM   3121  N  N     . ALA   C 3 327 ? 20.381  75.390  -17.376 1.00 27.74  ? 620  ALA   A N     1 
ATOM   3122  C  CA    . ALA   C 3 327 ? 19.133  76.029  -17.747 1.00 29.63  ? 620  ALA   A CA    1 
ATOM   3123  C  C     . ALA   C 3 327 ? 19.032  76.148  -19.273 1.00 28.66  ? 620  ALA   A C     1 
ATOM   3124  O  O     . ALA   C 3 327 ? 17.986  75.853  -19.858 1.00 30.73  ? 620  ALA   A O     1 
ATOM   3125  C  CB    . ALA   C 3 327 ? 19.055  77.373  -17.072 1.00 30.08  ? 620  ALA   A CB    1 
ATOM   3126  N  N     . HIS   C 3 328 ? 20.128  76.545  -19.923 1.00 29.49  ? 621  HIS   A N     1 
ATOM   3127  C  CA    . HIS   C 3 328 ? 20.187  76.602  -21.381 1.00 30.39  ? 621  HIS   A CA    1 
ATOM   3128  C  C     . HIS   C 3 328 ? 20.069  75.218  -22.021 1.00 30.39  ? 621  HIS   A C     1 
ATOM   3129  O  O     . HIS   C 3 328 ? 19.291  75.019  -22.949 1.00 30.93  ? 621  HIS   A O     1 
ATOM   3130  C  CB    . HIS   C 3 328 ? 21.486  77.249  -21.851 1.00 31.73  ? 621  HIS   A CB    1 
ATOM   3131  C  CG    . HIS   C 3 328 ? 21.588  77.334  -23.340 1.00 32.91  ? 621  HIS   A CG    1 
ATOM   3132  N  ND1   . HIS   C 3 328 ? 21.043  78.348  -24.087 1.00 34.85  ? 621  HIS   A ND1   1 
ATOM   3133  C  CD2   . HIS   C 3 328 ? 22.173  76.464  -24.206 1.00 34.02  ? 621  HIS   A CD2   1 
ATOM   3134  C  CE1   . HIS   C 3 328 ? 21.276  78.103  -25.373 1.00 36.42  ? 621  HIS   A CE1   1 
ATOM   3135  N  NE2   . HIS   C 3 328 ? 21.985  76.942  -25.469 1.00 33.71  ? 621  HIS   A NE2   1 
ATOM   3136  N  N     . LEU   C 3 329 ? 20.873  74.258  -21.565 1.00 29.05  ? 622  LEU   A N     1 
ATOM   3137  C  CA    . LEU   C 3 329 ? 20.857  72.939  -22.182 1.00 28.69  ? 622  LEU   A CA    1 
ATOM   3138  C  C     . LEU   C 3 329 ? 19.480  72.291  -22.060 1.00 30.05  ? 622  LEU   A C     1 
ATOM   3139  O  O     . LEU   C 3 329 ? 19.022  71.629  -22.982 1.00 32.34  ? 622  LEU   A O     1 
ATOM   3140  C  CB    . LEU   C 3 329 ? 21.916  72.060  -21.514 1.00 28.52  ? 622  LEU   A CB    1 
ATOM   3141  C  CG    . LEU   C 3 329 ? 23.362  72.449  -21.810 1.00 27.94  ? 622  LEU   A CG    1 
ATOM   3142  C  CD1   . LEU   C 3 329 ? 24.322  71.487  -21.117 1.00 28.80  ? 622  LEU   A CD1   1 
ATOM   3143  C  CD2   . LEU   C 3 329 ? 23.619  72.497  -23.316 1.00 24.99  ? 622  LEU   A CD2   1 
ATOM   3144  N  N     . SER   C 3 330 ? 18.846  72.449  -20.896 1.00 29.66  ? 623  SER   A N     1 
ATOM   3145  C  CA    . SER   C 3 330 ? 17.601  71.761  -20.591 1.00 29.12  ? 623  SER   A CA    1 
ATOM   3146  C  C     . SER   C 3 330 ? 16.381  72.549  -21.069 1.00 29.93  ? 623  SER   A C     1 
ATOM   3147  O  O     . SER   C 3 330 ? 15.302  71.979  -21.228 1.00 30.78  ? 623  SER   A O     1 
ATOM   3148  C  CB    . SER   C 3 330 ? 17.510  71.529  -19.107 1.00 28.89  ? 623  SER   A CB    1 
ATOM   3149  O  OG    . SER   C 3 330 ? 17.322  72.773  -18.424 1.00 28.25  ? 623  SER   A OG    1 
ATOM   3150  N  N     . GLY   C 3 331 ? 16.531  73.873  -21.200 1.00 31.50  ? 624  GLY   A N     1 
ATOM   3151  C  CA    . GLY   C 3 331 ? 15.420  74.775  -21.463 1.00 33.36  ? 624  GLY   A CA    1 
ATOM   3152  C  C     . GLY   C 3 331 ? 14.434  74.891  -20.296 1.00 35.71  ? 624  GLY   A C     1 
ATOM   3153  O  O     . GLY   C 3 331 ? 13.318  75.375  -20.474 1.00 38.64  ? 624  GLY   A O     1 
ATOM   3154  N  N     . ASP   C 3 332 ? 14.842  74.491  -19.090 1.00 37.89  ? 625  ASP   A N     1 
ATOM   3155  C  CA    . ASP   C 3 332 ? 13.921  74.457  -17.967 1.00 36.46  ? 625  ASP   A CA    1 
ATOM   3156  C  C     . ASP   C 3 332 ? 13.574  75.878  -17.545 1.00 35.75  ? 625  ASP   A C     1 
ATOM   3157  O  O     . ASP   C 3 332 ? 14.419  76.590  -17.013 1.00 35.19  ? 625  ASP   A O     1 
ATOM   3158  C  CB    . ASP   C 3 332 ? 14.476  73.669  -16.780 1.00 36.59  ? 625  ASP   A CB    1 
ATOM   3159  C  CG    . ASP   C 3 332 ? 13.415  73.488  -15.703 1.00 37.98  ? 625  ASP   A CG    1 
ATOM   3160  O  OD1   . ASP   C 3 332 ? 13.086  74.491  -15.031 1.00 38.18  ? 625  ASP   A OD1   1 
ATOM   3161  O  OD2   . ASP   C 3 332 ? 12.892  72.366  -15.581 1.00 33.15  ? 625  ASP   A OD2   1 
ATOM   3162  N  N     . GLU   C 3 333 ? 12.312  76.280  -17.715 1.00 37.45  ? 626  GLU   A N     1 
ATOM   3163  C  CA    . GLU   C 3 333 ? 12.006  77.698  -17.585 1.00 41.35  ? 626  GLU   A CA    1 
ATOM   3164  C  C     . GLU   C 3 333 ? 11.839  78.086  -16.120 1.00 39.07  ? 626  GLU   A C     1 
ATOM   3165  O  O     . GLU   C 3 333 ? 11.936  79.279  -15.806 1.00 38.53  ? 626  GLU   A O     1 
ATOM   3166  C  CB    . GLU   C 3 333 ? 10.858  78.149  -18.490 1.00 48.31  ? 626  GLU   A CB    1 
ATOM   3167  C  CG    . GLU   C 3 333 ? 9.735   77.163  -18.595 1.00 54.49  ? 626  GLU   A CG    1 
ATOM   3168  C  CD    . GLU   C 3 333 ? 9.767   76.112  -19.692 1.00 49.55  ? 626  GLU   A CD    1 
ATOM   3169  O  OE1   . GLU   C 3 333 ? 9.395   76.450  -20.821 1.00 56.36  ? 626  GLU   A OE1   1 
ATOM   3170  O  OE2   . GLU   C 3 333 ? 10.035  74.935  -19.376 1.00 50.70  ? 626  GLU   A OE2   1 
ATOM   3171  N  N     . ASN   C 3 334 ? 11.699  77.099  -15.215 1.00 34.55  ? 627  ASN   A N     1 
ATOM   3172  C  CA    . ASN   C 3 334 ? 11.705  77.414  -13.791 1.00 37.46  ? 627  ASN   A CA    1 
ATOM   3173  C  C     . ASN   C 3 334 ? 13.136  77.761  -13.394 1.00 39.68  ? 627  ASN   A C     1 
ATOM   3174  O  O     . ASN   C 3 334 ? 13.369  78.673  -12.604 1.00 36.92  ? 627  ASN   A O     1 
ATOM   3175  C  CB    . ASN   C 3 334 ? 11.109  76.302  -12.907 1.00 40.89  ? 627  ASN   A CB    1 
ATOM   3176  C  CG    . ASN   C 3 334 ? 9.608   76.129  -13.092 1.00 44.84  ? 627  ASN   A CG    1 
ATOM   3177  O  OD1   . ASN   C 3 334 ? 9.157   75.557  -14.085 1.00 45.78  ? 627  ASN   A OD1   1 
ATOM   3178  N  ND2   . ASN   C 3 334 ? 8.818   76.617  -12.143 1.00 40.99  ? 627  ASN   A ND2   1 
ATOM   3179  N  N     . LEU   C 3 335 ? 14.105  77.049  -13.993 1.00 42.61  ? 628  LEU   A N     1 
ATOM   3180  C  CA    . LEU   C 3 335 ? 15.505  77.312  -13.715 1.00 38.39  ? 628  LEU   A CA    1 
ATOM   3181  C  C     . LEU   C 3 335 ? 15.920  78.630  -14.373 1.00 36.15  ? 628  LEU   A C     1 
ATOM   3182  O  O     . LEU   C 3 335 ? 16.606  79.438  -13.757 1.00 38.17  ? 628  LEU   A O     1 
ATOM   3183  C  CB    . LEU   C 3 335 ? 16.329  76.108  -14.181 1.00 39.48  ? 628  LEU   A CB    1 
ATOM   3184  C  CG    . LEU   C 3 335 ? 17.766  76.083  -13.666 1.00 42.95  ? 628  LEU   A CG    1 
ATOM   3185  C  CD1   . LEU   C 3 335 ? 17.775  76.080  -12.146 1.00 44.85  ? 628  LEU   A CD1   1 
ATOM   3186  C  CD2   . LEU   C 3 335 ? 18.531  74.892  -14.218 1.00 40.26  ? 628  LEU   A CD2   1 
ATOM   3187  N  N     . ILE   C 3 336 ? 15.440  78.893  -15.592 1.00 38.65  ? 629  ILE   A N     1 
ATOM   3188  C  CA    . ILE   C 3 336 ? 15.679  80.171  -16.255 1.00 36.56  ? 629  ILE   A CA    1 
ATOM   3189  C  C     . ILE   C 3 336 ? 15.129  81.306  -15.390 1.00 37.86  ? 629  ILE   A C     1 
ATOM   3190  O  O     . ILE   C 3 336 ? 15.742  82.367  -15.296 1.00 46.42  ? 629  ILE   A O     1 
ATOM   3191  C  CB    . ILE   C 3 336 ? 15.081  80.155  -17.679 1.00 36.46  ? 629  ILE   A CB    1 
ATOM   3192  C  CG1   . ILE   C 3 336 ? 15.829  79.177  -18.587 1.00 35.60  ? 629  ILE   A CG1   1 
ATOM   3193  C  CG2   . ILE   C 3 336 ? 15.032  81.540  -18.312 1.00 35.91  ? 629  ILE   A CG2   1 
ATOM   3194  C  CD1   . ILE   C 3 336 ? 15.113  78.898  -19.906 1.00 37.21  ? 629  ILE   A CD1   1 
ATOM   3195  N  N     . ARG   C 3 337 ? 14.005  81.061  -14.707 1.00 39.63  ? 630  ARG   A N     1 
ATOM   3196  C  CA    . ARG   C 3 337 ? 13.334  82.074  -13.900 1.00 40.98  ? 630  ARG   A CA    1 
ATOM   3197  C  C     . ARG   C 3 337 ? 14.155  82.461  -12.668 1.00 36.96  ? 630  ARG   A C     1 
ATOM   3198  O  O     . ARG   C 3 337 ? 14.157  83.619  -12.252 1.00 36.66  ? 630  ARG   A O     1 
ATOM   3199  C  CB    . ARG   C 3 337 ? 11.956  81.556  -13.461 1.00 51.85  ? 630  ARG   A CB    1 
ATOM   3200  C  CG    . ARG   C 3 337 ? 11.154  82.535  -12.612 1.00 58.76  ? 630  ARG   A CG    1 
ATOM   3201  C  CD    . ARG   C 3 337 ? 10.742  83.704  -13.490 1.00 64.75  ? 630  ARG   A CD    1 
ATOM   3202  N  NE    . ARG   C 3 337 ? 10.133  84.833  -12.798 1.00 66.42  ? 630  ARG   A NE    1 
ATOM   3203  C  CZ    . ARG   C 3 337 ? 9.884   85.996  -13.390 1.00 65.41  ? 630  ARG   A CZ    1 
ATOM   3204  N  NH1   . ARG   C 3 337 ? 10.241  86.174  -14.651 1.00 62.35  ? 630  ARG   A NH1   1 
ATOM   3205  N  NH2   . ARG   C 3 337 ? 9.277   86.964  -12.728 1.00 69.19  ? 630  ARG   A NH2   1 
ATOM   3206  N  N     . VAL   C 3 338 ? 14.791  81.479  -12.027 1.00 35.95  ? 631  VAL   A N     1 
ATOM   3207  C  CA    . VAL   C 3 338 ? 15.695  81.748  -10.917 1.00 38.76  ? 631  VAL   A CA    1 
ATOM   3208  C  C     . VAL   C 3 338 ? 16.603  82.939  -11.235 1.00 39.67  ? 631  VAL   A C     1 
ATOM   3209  O  O     . VAL   C 3 338 ? 16.726  83.852  -10.424 1.00 42.16  ? 631  VAL   A O     1 
ATOM   3210  C  CB    . VAL   C 3 338 ? 16.532  80.503  -10.558 1.00 40.42  ? 631  VAL   A CB    1 
ATOM   3211  C  CG1   . VAL   C 3 338 ? 17.705  80.846  -9.655  1.00 40.25  ? 631  VAL   A CG1   1 
ATOM   3212  C  CG2   . VAL   C 3 338 ? 15.688  79.417  -9.917  1.00 41.69  ? 631  VAL   A CG2   1 
ATOM   3213  N  N     . PHE   C 3 339 ? 17.232  82.924  -12.419 1.00 41.60  ? 632  PHE   A N     1 
ATOM   3214  C  CA    . PHE   C 3 339 ? 18.226  83.922  -12.803 1.00 39.08  ? 632  PHE   A CA    1 
ATOM   3215  C  C     . PHE   C 3 339 ? 17.572  85.252  -13.172 1.00 42.23  ? 632  PHE   A C     1 
ATOM   3216  O  O     . PHE   C 3 339 ? 18.030  86.299  -12.717 1.00 44.40  ? 632  PHE   A O     1 
ATOM   3217  C  CB    . PHE   C 3 339 ? 19.101  83.350  -13.920 1.00 36.17  ? 632  PHE   A CB    1 
ATOM   3218  C  CG    . PHE   C 3 339 ? 19.785  82.089  -13.460 1.00 36.18  ? 632  PHE   A CG    1 
ATOM   3219  C  CD1   . PHE   C 3 339 ? 20.728  82.136  -12.445 1.00 37.87  ? 632  PHE   A CD1   1 
ATOM   3220  C  CD2   . PHE   C 3 339 ? 19.411  80.858  -13.954 1.00 32.97  ? 632  PHE   A CD2   1 
ATOM   3221  C  CE1   . PHE   C 3 339 ? 21.332  80.977  -11.991 1.00 37.46  ? 632  PHE   A CE1   1 
ATOM   3222  C  CE2   . PHE   C 3 339 ? 20.002  79.700  -13.483 1.00 36.71  ? 632  PHE   A CE2   1 
ATOM   3223  C  CZ    . PHE   C 3 339 ? 20.947  79.759  -12.489 1.00 37.42  ? 632  PHE   A CZ    1 
ATOM   3224  N  N     . GLN   C 3 340 ? 16.477  85.209  -13.943 1.00 42.90  ? 633  GLN   A N     1 
ATOM   3225  C  CA    . GLN   C 3 340 ? 15.748  86.416  -14.302 1.00 46.37  ? 633  GLN   A CA    1 
ATOM   3226  C  C     . GLN   C 3 340 ? 15.279  87.178  -13.058 1.00 46.47  ? 633  GLN   A C     1 
ATOM   3227  O  O     . GLN   C 3 340 ? 15.178  88.398  -13.118 1.00 52.85  ? 633  GLN   A O     1 
ATOM   3228  C  CB    . GLN   C 3 340 ? 14.593  86.064  -15.243 1.00 49.47  ? 633  GLN   A CB    1 
ATOM   3229  C  CG    . GLN   C 3 340 ? 15.088  85.721  -16.652 1.00 54.95  ? 633  GLN   A CG    1 
ATOM   3230  C  CD    . GLN   C 3 340 ? 14.064  85.135  -17.602 1.00 58.68  ? 633  GLN   A CD    1 
ATOM   3231  O  OE1   . GLN   C 3 340 ? 14.382  84.893  -18.768 1.00 52.08  ? 633  GLN   A OE1   1 
ATOM   3232  N  NE2   . GLN   C 3 340 ? 12.843  84.902  -17.120 1.00 53.10  ? 633  GLN   A NE2   1 
ATOM   3233  N  N     . GLU   C 3 341 ? 15.015  86.478  -11.942 1.00 42.49  ? 634  GLU   A N     1 
ATOM   3234  C  CA    . GLU   C 3 341 ? 14.621  87.115  -10.691 1.00 46.04  ? 634  GLU   A CA    1 
ATOM   3235  C  C     . GLU   C 3 341 ? 15.809  87.475  -9.797  1.00 45.07  ? 634  GLU   A C     1 
ATOM   3236  O  O     . GLU   C 3 341 ? 15.601  88.005  -8.711  1.00 45.74  ? 634  GLU   A O     1 
ATOM   3237  C  CB    . GLU   C 3 341 ? 13.761  86.184  -9.839  1.00 49.18  ? 634  GLU   A CB    1 
ATOM   3238  C  CG    . GLU   C 3 341 ? 12.363  85.954  -10.368 1.00 55.22  ? 634  GLU   A CG    1 
ATOM   3239  C  CD    . GLU   C 3 341 ? 11.457  85.368  -9.296  1.00 63.97  ? 634  GLU   A CD    1 
ATOM   3240  O  OE1   . GLU   C 3 341 ? 11.265  84.122  -9.295  1.00 63.29  ? 634  GLU   A OE1   1 
ATOM   3241  O  OE2   . GLU   C 3 341 ? 10.961  86.163  -8.444  1.00 73.56  ? 634  GLU   A OE2   1 
ATOM   3242  N  N     . GLY   C 3 342 ? 17.043  87.166  -10.220 1.00 45.18  ? 635  GLY   A N     1 
ATOM   3243  C  CA    . GLY   C 3 342 ? 18.221  87.471  -9.425  1.00 38.91  ? 635  GLY   A CA    1 
ATOM   3244  C  C     . GLY   C 3 342 ? 18.272  86.662  -8.130  1.00 39.20  ? 635  GLY   A C     1 
ATOM   3245  O  O     . GLY   C 3 342 ? 18.859  87.107  -7.153  1.00 43.89  ? 635  GLY   A O     1 
ATOM   3246  N  N     . ARG   C 3 343 ? 17.698  85.450  -8.131  1.00 40.23  ? 636  ARG   A N     1 
ATOM   3247  C  CA    . ARG   C 3 343 ? 17.840  84.540  -7.001  1.00 38.46  ? 636  ARG   A CA    1 
ATOM   3248  C  C     . ARG   C 3 343 ? 19.162  83.777  -7.075  1.00 39.96  ? 636  ARG   A C     1 
ATOM   3249  O  O     . ARG   C 3 343 ? 19.745  83.566  -8.142  1.00 41.94  ? 636  ARG   A O     1 
ATOM   3250  C  CB    . ARG   C 3 343 ? 16.682  83.536  -6.956  1.00 41.99  ? 636  ARG   A CB    1 
ATOM   3251  C  CG    . ARG   C 3 343 ? 15.329  84.158  -6.616  1.00 42.71  ? 636  ARG   A CG    1 
ATOM   3252  C  CD    . ARG   C 3 343 ? 14.355  83.160  -6.031  1.00 43.48  ? 636  ARG   A CD    1 
ATOM   3253  N  NE    . ARG   C 3 343 ? 13.948  82.121  -6.950  1.00 41.04  ? 636  ARG   A NE    1 
ATOM   3254  C  CZ    . ARG   C 3 343 ? 13.619  80.880  -6.615  1.00 41.60  ? 636  ARG   A CZ    1 
ATOM   3255  N  NH1   . ARG   C 3 343 ? 14.175  80.263  -5.595  1.00 39.35  ? 636  ARG   A NH1   1 
ATOM   3256  N  NH2   . ARG   C 3 343 ? 12.737  80.233  -7.351  1.00 49.70  ? 636  ARG   A NH2   1 
ATOM   3257  N  N     . ASP   C 3 344 ? 19.595  83.324  -5.901  1.00 38.80  ? 637  ASP   A N     1 
ATOM   3258  C  CA    . ASP   C 3 344 ? 20.787  82.520  -5.733  1.00 37.40  ? 637  ASP   A CA    1 
ATOM   3259  C  C     . ASP   C 3 344 ? 20.386  81.281  -4.939  1.00 33.55  ? 637  ASP   A C     1 
ATOM   3260  O  O     . ASP   C 3 344 ? 20.111  81.382  -3.742  1.00 36.97  ? 637  ASP   A O     1 
ATOM   3261  C  CB    . ASP   C 3 344 ? 21.885  83.359  -5.054  1.00 38.83  ? 637  ASP   A CB    1 
ATOM   3262  C  CG    . ASP   C 3 344 ? 23.224  82.647  -4.917  1.00 42.72  ? 637  ASP   A CG    1 
ATOM   3263  O  OD1   . ASP   C 3 344 ? 23.224  81.449  -4.592  1.00 45.15  ? 637  ASP   A OD1   1 
ATOM   3264  O  OD2   . ASP   C 3 344 ? 24.249  83.294  -5.133  1.00 50.24  ? 637  ASP   A OD2   1 
ATOM   3265  N  N     . ILE   C 3 345 ? 20.378  80.113  -5.590  1.00 38.22  ? 638  ILE   A N     1 
ATOM   3266  C  CA    . ILE   C 3 345 ? 19.900  78.888  -4.955  1.00 38.25  ? 638  ILE   A CA    1 
ATOM   3267  C  C     . ILE   C 3 345 ? 20.946  78.324  -3.996  1.00 33.32  ? 638  ILE   A C     1 
ATOM   3268  O  O     . ILE   C 3 345 ? 20.626  77.540  -3.104  1.00 31.99  ? 638  ILE   A O     1 
ATOM   3269  C  CB    . ILE   C 3 345 ? 19.448  77.839  -5.995  1.00 45.51  ? 638  ILE   A CB    1 
ATOM   3270  C  CG1   . ILE   C 3 345 ? 20.620  77.097  -6.633  1.00 55.17  ? 638  ILE   A CG1   1 
ATOM   3271  C  CG2   . ILE   C 3 345 ? 18.556  78.476  -7.049  1.00 46.13  ? 638  ILE   A CG2   1 
ATOM   3272  C  CD1   . ILE   C 3 345 ? 20.201  75.871  -7.421  1.00 63.39  ? 638  ILE   A CD1   1 
ATOM   3273  N  N     . HIS   C 3 346 ? 22.214  78.688  -4.182  1.00 32.43  ? 639  HIS   A N     1 
ATOM   3274  C  CA    . HIS   C 3 346 ? 23.210  78.300  -3.199  1.00 31.74  ? 639  HIS   A CA    1 
ATOM   3275  C  C     . HIS   C 3 346 ? 22.905  78.984  -1.865  1.00 32.96  ? 639  HIS   A C     1 
ATOM   3276  O  O     . HIS   C 3 346 ? 22.896  78.318  -0.828  1.00 33.07  ? 639  HIS   A O     1 
ATOM   3277  C  CB    . HIS   C 3 346 ? 24.628  78.601  -3.707  1.00 31.97  ? 639  HIS   A CB    1 
ATOM   3278  C  CG    . HIS   C 3 346 ? 25.034  77.849  -4.937  1.00 30.13  ? 639  HIS   A CG    1 
ATOM   3279  N  ND1   . HIS   C 3 346 ? 24.655  76.555  -5.207  1.00 29.33  ? 639  HIS   A ND1   1 
ATOM   3280  C  CD2   . HIS   C 3 346 ? 25.789  78.282  -5.985  1.00 28.36  ? 639  HIS   A CD2   1 
ATOM   3281  C  CE1   . HIS   C 3 346 ? 25.177  76.197  -6.378  1.00 27.70  ? 639  HIS   A CE1   1 
ATOM   3282  N  NE2   . HIS   C 3 346 ? 25.879  77.258  -6.880  1.00 26.94  ? 639  HIS   A NE2   1 
ATOM   3283  N  N     . THR   C 3 347 ? 22.632  80.304  -1.902  1.00 35.64  ? 640  THR   A N     1 
ATOM   3284  C  CA    . THR   C 3 347 ? 22.224  81.048  -0.714  1.00 39.72  ? 640  THR   A CA    1 
ATOM   3285  C  C     . THR   C 3 347 ? 20.915  80.484  -0.141  1.00 39.85  ? 640  THR   A C     1 
ATOM   3286  O  O     . THR   C 3 347 ? 20.783  80.279  1.071   1.00 41.02  ? 640  THR   A O     1 
ATOM   3287  C  CB    . THR   C 3 347 ? 22.071  82.547  -1.016  1.00 44.87  ? 640  THR   A CB    1 
ATOM   3288  O  OG1   . THR   C 3 347 ? 23.233  83.014  -1.701  1.00 45.58  ? 640  THR   A OG1   1 
ATOM   3289  C  CG2   . THR   C 3 347 ? 21.867  83.379  0.234   1.00 45.80  ? 640  THR   A CG2   1 
ATOM   3290  N  N     . GLU   C 3 348 ? 19.933  80.229  -1.009  1.00 37.84  ? 641  GLU   A N     1 
ATOM   3291  C  CA    . GLU   C 3 348 ? 18.649  79.734  -0.537  1.00 36.67  ? 641  GLU   A CA    1 
ATOM   3292  C  C     . GLU   C 3 348 ? 18.829  78.406  0.187   1.00 36.17  ? 641  GLU   A C     1 
ATOM   3293  O  O     . GLU   C 3 348 ? 18.259  78.209  1.256   1.00 36.37  ? 641  GLU   A O     1 
ATOM   3294  C  CB    . GLU   C 3 348 ? 17.664  79.589  -1.693  1.00 37.13  ? 641  GLU   A CB    1 
ATOM   3295  C  CG    . GLU   C 3 348 ? 17.129  80.931  -2.159  1.00 38.77  ? 641  GLU   A CG    1 
ATOM   3296  C  CD    . GLU   C 3 348 ? 16.206  80.898  -3.364  1.00 37.29  ? 641  GLU   A CD    1 
ATOM   3297  O  OE1   . GLU   C 3 348 ? 15.812  79.789  -3.783  1.00 36.45  ? 641  GLU   A OE1   1 
ATOM   3298  O  OE2   . GLU   C 3 348 ? 15.905  81.986  -3.881  1.00 38.29  ? 641  GLU   A OE2   1 
ATOM   3299  N  N     . THR   C 3 349 ? 19.645  77.502  -0.369  1.00 33.65  ? 642  THR   A N     1 
ATOM   3300  C  CA    . THR   C 3 349 ? 19.847  76.214  0.281   1.00 33.06  ? 642  THR   A CA    1 
ATOM   3301  C  C     . THR   C 3 349 ? 20.587  76.395  1.610   1.00 33.84  ? 642  THR   A C     1 
ATOM   3302  O  O     . THR   C 3 349 ? 20.248  75.770  2.617   1.00 34.96  ? 642  THR   A O     1 
ATOM   3303  C  CB    . THR   C 3 349 ? 20.567  75.239  -0.651  1.00 31.57  ? 642  THR   A CB    1 
ATOM   3304  O  OG1   . THR   C 3 349 ? 19.735  75.043  -1.792  1.00 30.58  ? 642  THR   A OG1   1 
ATOM   3305  C  CG2   . THR   C 3 349 ? 20.884  73.918  0.005   1.00 31.23  ? 642  THR   A CG2   1 
ATOM   3306  N  N     . ALA   C 3 350 ? 21.614  77.240  1.616   1.00 34.26  ? 643  ALA   A N     1 
ATOM   3307  C  CA    . ALA   C 3 350 ? 22.433  77.426  2.809   1.00 40.84  ? 643  ALA   A CA    1 
ATOM   3308  C  C     . ALA   C 3 350 ? 21.592  77.981  3.969   1.00 39.74  ? 643  ALA   A C     1 
ATOM   3309  O  O     . ALA   C 3 350 ? 21.692  77.508  5.099   1.00 42.58  ? 643  ALA   A O     1 
ATOM   3310  C  CB    . ALA   C 3 350 ? 23.604  78.326  2.476   1.00 39.50  ? 643  ALA   A CB    1 
ATOM   3311  N  N     . SER   C 3 351 ? 20.759  78.980  3.675   1.00 41.79  ? 644  SER   A N     1 
ATOM   3312  C  CA    . SER   C 3 351 ? 19.849  79.568  4.649   1.00 50.59  ? 644  SER   A CA    1 
ATOM   3313  C  C     . SER   C 3 351 ? 19.012  78.499  5.361   1.00 47.29  ? 644  SER   A C     1 
ATOM   3314  O  O     . SER   C 3 351 ? 18.947  78.470  6.593   1.00 46.98  ? 644  SER   A O     1 
ATOM   3315  C  CB    . SER   C 3 351 ? 18.958  80.598  3.992   1.00 50.73  ? 644  SER   A CB    1 
ATOM   3316  O  OG    . SER   C 3 351 ? 18.292  81.345  4.987   1.00 60.92  ? 644  SER   A OG    1 
ATOM   3317  N  N     . TRP   C 3 352 ? 18.392  77.594  4.597   1.00 45.47  ? 645  TRP   A N     1 
ATOM   3318  C  CA    . TRP   C 3 352 ? 17.584  76.574  5.250   1.00 52.05  ? 645  TRP   A CA    1 
ATOM   3319  C  C     . TRP   C 3 352 ? 18.467  75.539  5.944   1.00 49.00  ? 645  TRP   A C     1 
ATOM   3320  O  O     . TRP   C 3 352 ? 18.117  75.094  7.036   1.00 51.83  ? 645  TRP   A O     1 
ATOM   3321  C  CB    . TRP   C 3 352 ? 16.480  75.982  4.348   1.00 56.17  ? 645  TRP   A CB    1 
ATOM   3322  C  CG    . TRP   C 3 352 ? 16.843  74.871  3.420   1.00 62.77  ? 645  TRP   A CG    1 
ATOM   3323  C  CD1   . TRP   C 3 352 ? 17.080  74.997  2.085   1.00 71.94  ? 645  TRP   A CD1   1 
ATOM   3324  C  CD2   . TRP   C 3 352 ? 16.876  73.460  3.703   1.00 74.35  ? 645  TRP   A CD2   1 
ATOM   3325  N  NE1   . TRP   C 3 352 ? 17.339  73.771  1.532   1.00 77.62  ? 645  TRP   A NE1   1 
ATOM   3326  C  CE2   . TRP   C 3 352 ? 17.238  72.810  2.503   1.00 75.10  ? 645  TRP   A CE2   1 
ATOM   3327  C  CE3   . TRP   C 3 352 ? 16.697  72.692  4.859   1.00 88.82  ? 645  TRP   A CE3   1 
ATOM   3328  C  CZ2   . TRP   C 3 352 ? 17.404  71.429  2.423   1.00 76.35  ? 645  TRP   A CZ2   1 
ATOM   3329  C  CZ3   . TRP   C 3 352 ? 16.868  71.325  4.781   1.00 92.91  ? 645  TRP   A CZ3   1 
ATOM   3330  C  CH2   . TRP   C 3 352 ? 17.212  70.704  3.576   1.00 88.32  ? 645  TRP   A CH2   1 
ATOM   3331  N  N     . MET   C 3 353 ? 19.628  75.196  5.369   1.00 50.10  ? 646  MET   A N     1 
ATOM   3332  C  CA    . MET   C 3 353 ? 20.487  74.176  5.953   1.00 42.51  ? 646  MET   A CA    1 
ATOM   3333  C  C     . MET   C 3 353 ? 20.948  74.595  7.346   1.00 41.29  ? 646  MET   A C     1 
ATOM   3334  O  O     . MET   C 3 353 ? 20.954  73.780  8.256   1.00 39.10  ? 646  MET   A O     1 
ATOM   3335  C  CB    . MET   C 3 353 ? 21.740  73.984  5.104   1.00 46.09  ? 646  MET   A CB    1 
ATOM   3336  C  CG    . MET   C 3 353 ? 21.565  72.997  3.983   1.00 48.09  ? 646  MET   A CG    1 
ATOM   3337  S  SD    . MET   C 3 353 ? 23.039  73.031  2.953   1.00 42.09  ? 646  MET   A SD    1 
ATOM   3338  C  CE    . MET   C 3 353 ? 24.007  71.783  3.806   1.00 38.15  ? 646  MET   A CE    1 
ATOM   3339  N  N     . PHE   C 3 354 ? 21.411  75.846  7.463   1.00 40.24  ? 647  PHE   A N     1 
ATOM   3340  C  CA    . PHE   C 3 354 ? 22.082  76.321  8.664   1.00 50.19  ? 647  PHE   A CA    1 
ATOM   3341  C  C     . PHE   C 3 354 ? 21.128  77.142  9.536   1.00 51.91  ? 647  PHE   A C     1 
ATOM   3342  O  O     . PHE   C 3 354 ? 21.436  77.408  10.692  1.00 54.32  ? 647  PHE   A O     1 
ATOM   3343  C  CB    . PHE   C 3 354 ? 23.361  77.080  8.274   1.00 50.89  ? 647  PHE   A CB    1 
ATOM   3344  C  CG    . PHE   C 3 354 ? 24.423  76.186  7.680   1.00 48.71  ? 647  PHE   A CG    1 
ATOM   3345  C  CD1   . PHE   C 3 354 ? 25.168  75.334  8.488   1.00 48.41  ? 647  PHE   A CD1   1 
ATOM   3346  C  CD2   . PHE   C 3 354 ? 24.616  76.128  6.301   1.00 47.65  ? 647  PHE   A CD2   1 
ATOM   3347  C  CE1   . PHE   C 3 354 ? 26.122  74.485  7.939   1.00 50.20  ? 647  PHE   A CE1   1 
ATOM   3348  C  CE2   . PHE   C 3 354 ? 25.560  75.275  5.754   1.00 47.66  ? 647  PHE   A CE2   1 
ATOM   3349  C  CZ    . PHE   C 3 354 ? 26.313  74.453  6.571   1.00 49.76  ? 647  PHE   A CZ    1 
ATOM   3350  N  N     . GLY   C 3 355 ? 19.969  77.529  8.984   1.00 50.28  ? 648  GLY   A N     1 
ATOM   3351  C  CA    . GLY   C 3 355 ? 18.935  78.201  9.746   1.00 48.33  ? 648  GLY   A CA    1 
ATOM   3352  C  C     . GLY   C 3 355 ? 19.380  79.604  10.134  1.00 50.42  ? 648  GLY   A C     1 
ATOM   3353  O  O     . GLY   C 3 355 ? 19.430  79.940  11.315  1.00 55.75  ? 648  GLY   A O     1 
ATOM   3354  N  N     . VAL   C 3 356 ? 19.730  80.381  9.105   1.00 49.49  ? 649  VAL   A N     1 
ATOM   3355  C  CA    . VAL   C 3 356 ? 20.237  81.731  9.247   1.00 49.18  ? 649  VAL   A CA    1 
ATOM   3356  C  C     . VAL   C 3 356 ? 19.768  82.507  8.025   1.00 47.32  ? 649  VAL   A C     1 
ATOM   3357  O  O     . VAL   C 3 356 ? 19.505  81.914  6.986   1.00 44.33  ? 649  VAL   A O     1 
ATOM   3358  C  CB    . VAL   C 3 356 ? 21.780  81.782  9.349   1.00 52.37  ? 649  VAL   A CB    1 
ATOM   3359  C  CG1   . VAL   C 3 356 ? 22.323  80.885  10.459  1.00 53.49  ? 649  VAL   A CG1   1 
ATOM   3360  C  CG2   . VAL   C 3 356 ? 22.448  81.449  8.018   1.00 49.06  ? 649  VAL   A CG2   1 
ATOM   3361  N  N     . PRO   C 3 357 ? 19.650  83.848  8.122   1.00 49.53  ? 650  PRO   A N     1 
ATOM   3362  C  CA    . PRO   C 3 357 ? 19.325  84.681  6.966   1.00 50.75  ? 650  PRO   A CA    1 
ATOM   3363  C  C     . PRO   C 3 357 ? 20.365  84.593  5.853   1.00 54.72  ? 650  PRO   A C     1 
ATOM   3364  O  O     . PRO   C 3 357 ? 21.480  84.156  6.100   1.00 56.71  ? 650  PRO   A O     1 
ATOM   3365  C  CB    . PRO   C 3 357 ? 19.283  86.111  7.543   1.00 50.26  ? 650  PRO   A CB    1 
ATOM   3366  C  CG    . PRO   C 3 357 ? 19.050  85.922  9.028   1.00 50.92  ? 650  PRO   A CG    1 
ATOM   3367  C  CD    . PRO   C 3 357 ? 19.742  84.621  9.373   1.00 51.14  ? 650  PRO   A CD    1 
ATOM   3368  N  N     . ARG   C 3 358 ? 19.981  85.070  4.661   1.00 56.07  ? 651  ARG   A N     1 
ATOM   3369  C  CA    . ARG   C 3 358 ? 20.826  85.166  3.484   1.00 65.12  ? 651  ARG   A CA    1 
ATOM   3370  C  C     . ARG   C 3 358 ? 22.162  85.826  3.825   1.00 72.58  ? 651  ARG   A C     1 
ATOM   3371  O  O     . ARG   C 3 358 ? 23.213  85.324  3.422   1.00 76.27  ? 651  ARG   A O     1 
ATOM   3372  C  CB    . ARG   C 3 358 ? 20.123  85.987  2.391   1.00 71.38  ? 651  ARG   A CB    1 
ATOM   3373  C  CG    . ARG   C 3 358 ? 19.132  85.234  1.505   1.00 75.87  ? 651  ARG   A CG    1 
ATOM   3374  C  CD    . ARG   C 3 358 ? 17.985  84.534  2.209   1.00 76.61  ? 651  ARG   A CD    1 
ATOM   3375  N  NE    . ARG   C 3 358 ? 17.411  83.462  1.405   1.00 76.96  ? 651  ARG   A NE    1 
ATOM   3376  C  CZ    . ARG   C 3 358 ? 16.144  83.394  1.000   1.00 76.42  ? 651  ARG   A CZ    1 
ATOM   3377  N  NH1   . ARG   C 3 358 ? 15.519  82.229  1.015   1.00 75.41  ? 651  ARG   A NH1   1 
ATOM   3378  N  NH2   . ARG   C 3 358 ? 15.487  84.478  0.611   1.00 73.44  ? 651  ARG   A NH2   1 
ATOM   3379  N  N     . GLU   C 3 359 ? 22.108  86.958  4.549   1.00 76.22  ? 652  GLU   A N     1 
ATOM   3380  C  CA    . GLU   C 3 359 ? 23.271  87.808  4.769   1.00 73.98  ? 652  GLU   A CA    1 
ATOM   3381  C  C     . GLU   C 3 359 ? 24.277  87.146  5.708   1.00 67.67  ? 652  GLU   A C     1 
ATOM   3382  O  O     . GLU   C 3 359 ? 25.462  87.463  5.644   1.00 69.62  ? 652  GLU   A O     1 
ATOM   3383  C  CB    . GLU   C 3 359 ? 22.879  89.182  5.322   1.00 79.17  ? 652  GLU   A CB    1 
ATOM   3384  C  CG    . GLU   C 3 359 ? 22.076  90.019  4.341   1.00 92.91  ? 652  GLU   A CG    1 
ATOM   3385  C  CD    . GLU   C 3 359 ? 22.603  90.059  2.911   1.00 96.70  ? 652  GLU   A CD    1 
ATOM   3386  O  OE1   . GLU   C 3 359 ? 23.717  90.593  2.695   1.00 93.48  ? 652  GLU   A OE1   1 
ATOM   3387  O  OE2   . GLU   C 3 359 ? 21.898  89.547  2.013   1.00 97.04  ? 652  GLU   A OE2   1 
ATOM   3388  N  N     . ALA   C 3 360 ? 23.806  86.227  6.561   1.00 58.83  ? 653  ALA   A N     1 
ATOM   3389  C  CA    . ALA   C 3 360 ? 24.663  85.524  7.500   1.00 53.18  ? 653  ALA   A CA    1 
ATOM   3390  C  C     . ALA   C 3 360 ? 25.207  84.218  6.906   1.00 56.97  ? 653  ALA   A C     1 
ATOM   3391  O  O     . ALA   C 3 360 ? 25.787  83.404  7.636   1.00 56.12  ? 653  ALA   A O     1 
ATOM   3392  C  CB    . ALA   C 3 360 ? 23.903  85.262  8.775   1.00 50.84  ? 653  ALA   A CB    1 
ATOM   3393  N  N     . VAL   C 3 361 ? 25.043  84.010  5.589   1.00 51.16  ? 654  VAL   A N     1 
ATOM   3394  C  CA    . VAL   C 3 361 ? 25.623  82.841  4.940   1.00 51.54  ? 654  VAL   A CA    1 
ATOM   3395  C  C     . VAL   C 3 361 ? 27.115  83.104  4.733   1.00 45.29  ? 654  VAL   A C     1 
ATOM   3396  O  O     . VAL   C 3 361 ? 27.482  84.018  4.000   1.00 38.55  ? 654  VAL   A O     1 
ATOM   3397  C  CB    . VAL   C 3 361 ? 24.907  82.490  3.613   1.00 50.95  ? 654  VAL   A CB    1 
ATOM   3398  C  CG1   . VAL   C 3 361 ? 25.616  81.366  2.860   1.00 49.44  ? 654  VAL   A CG1   1 
ATOM   3399  C  CG2   . VAL   C 3 361 ? 23.448  82.122  3.843   1.00 48.74  ? 654  VAL   A CG2   1 
ATOM   3400  N  N     . ASN   C 3 362 ? 27.958  82.303  5.405   1.00 48.12  ? 655  ASN   A N     1 
ATOM   3401  C  CA    . ASN   C 3 362 ? 29.405  82.443  5.319   1.00 50.04  ? 655  ASN   A CA    1 
ATOM   3402  C  C     . ASN   C 3 362 ? 29.914  81.490  4.223   1.00 53.83  ? 655  ASN   A C     1 
ATOM   3403  O  O     . ASN   C 3 362 ? 29.205  80.575  3.794   1.00 53.56  ? 655  ASN   A O     1 
ATOM   3404  C  CB    . ASN   C 3 362 ? 30.061  82.293  6.707   1.00 41.12  ? 655  ASN   A CB    1 
ATOM   3405  C  CG    . ASN   C 3 362 ? 30.134  80.862  7.208   1.00 48.59  ? 655  ASN   A CG    1 
ATOM   3406  O  OD1   . ASN   C 3 362 ? 30.293  79.919  6.430   1.00 46.37  ? 655  ASN   A OD1   1 
ATOM   3407  N  ND2   . ASN   C 3 362 ? 30.009  80.669  8.514   1.00 46.66  ? 655  ASN   A ND2   1 
ATOM   3408  N  N     . PRO   C 3 363 ? 31.150  81.679  3.693   1.00 54.35  ? 656  PRO   A N     1 
ATOM   3409  C  CA    . PRO   C 3 363 ? 31.644  80.867  2.574   1.00 44.41  ? 656  PRO   A CA    1 
ATOM   3410  C  C     . PRO   C 3 363 ? 31.696  79.364  2.831   1.00 46.64  ? 656  PRO   A C     1 
ATOM   3411  O  O     . PRO   C 3 363 ? 31.546  78.562  1.906   1.00 47.26  ? 656  PRO   A O     1 
ATOM   3412  C  CB    . PRO   C 3 363 ? 33.064  81.415  2.349   1.00 50.90  ? 656  PRO   A CB    1 
ATOM   3413  C  CG    . PRO   C 3 363 ? 32.977  82.854  2.844   1.00 54.65  ? 656  PRO   A CG    1 
ATOM   3414  C  CD    . PRO   C 3 363 ? 32.105  82.739  4.083   1.00 53.30  ? 656  PRO   A CD    1 
ATOM   3415  N  N     . LEU   C 3 364 ? 31.903  78.981  4.090   1.00 43.80  ? 657  LEU   A N     1 
ATOM   3416  C  CA    . LEU   C 3 364 ? 31.863  77.583  4.456   1.00 46.89  ? 657  LEU   A CA    1 
ATOM   3417  C  C     . LEU   C 3 364 ? 30.463  77.038  4.153   1.00 45.64  ? 657  LEU   A C     1 
ATOM   3418  O  O     . LEU   C 3 364 ? 30.307  75.924  3.640   1.00 41.52  ? 657  LEU   A O     1 
ATOM   3419  C  CB    . LEU   C 3 364 ? 32.246  77.476  5.940   1.00 56.91  ? 657  LEU   A CB    1 
ATOM   3420  C  CG    . LEU   C 3 364 ? 32.357  76.064  6.529   1.00 67.68  ? 657  LEU   A CG    1 
ATOM   3421  C  CD1   . LEU   C 3 364 ? 33.611  75.362  6.044   1.00 72.76  ? 657  LEU   A CD1   1 
ATOM   3422  C  CD2   . LEU   C 3 364 ? 32.345  76.100  8.056   1.00 70.51  ? 657  LEU   A CD2   1 
ATOM   3423  N  N     . MET   C 3 365 ? 29.449  77.851  4.482   1.00 44.28  ? 658  MET   A N     1 
ATOM   3424  C  CA    . MET   C 3 365 ? 28.049  77.473  4.385   1.00 41.90  ? 658  MET   A CA    1 
ATOM   3425  C  C     . MET   C 3 365 ? 27.655  77.371  2.910   1.00 38.55  ? 658  MET   A C     1 
ATOM   3426  O  O     . MET   C 3 365 ? 26.999  76.418  2.497   1.00 37.07  ? 658  MET   A O     1 
ATOM   3427  C  CB    . MET   C 3 365 ? 27.167  78.522  5.077   1.00 43.61  ? 658  MET   A CB    1 
ATOM   3428  C  CG    . MET   C 3 365 ? 27.177  78.410  6.600   1.00 46.11  ? 658  MET   A CG    1 
ATOM   3429  S  SD    . MET   C 3 365 ? 26.274  79.746  7.415   1.00 51.63  ? 658  MET   A SD    1 
ATOM   3430  C  CE    . MET   C 3 365 ? 26.434  79.206  9.121   1.00 49.63  ? 658  MET   A CE    1 
ATOM   3431  N  N     . ARG   C 3 366 ? 28.078  78.364  2.126   1.00 33.85  ? 659  ARG   A N     1 
ATOM   3432  C  CA    . ARG   C 3 366 ? 27.788  78.383  0.706   1.00 37.74  ? 659  ARG   A CA    1 
ATOM   3433  C  C     . ARG   C 3 366 ? 28.357  77.121  0.039   1.00 37.63  ? 659  ARG   A C     1 
ATOM   3434  O  O     . ARG   C 3 366 ? 27.639  76.404  -0.669  1.00 36.37  ? 659  ARG   A O     1 
ATOM   3435  C  CB    . ARG   C 3 366 ? 28.295  79.702  0.131   1.00 36.39  ? 659  ARG   A CB    1 
ATOM   3436  C  CG    . ARG   C 3 366 ? 27.665  80.058  -1.206  1.00 42.33  ? 659  ARG   A CG    1 
ATOM   3437  C  CD    . ARG   C 3 366 ? 28.438  81.157  -1.907  1.00 39.78  ? 659  ARG   A CD    1 
ATOM   3438  N  NE    . ARG   C 3 366 ? 28.061  81.282  -3.311  1.00 40.75  ? 659  ARG   A NE    1 
ATOM   3439  C  CZ    . ARG   C 3 366 ? 26.872  81.687  -3.746  1.00 40.84  ? 659  ARG   A CZ    1 
ATOM   3440  N  NH1   . ARG   C 3 366 ? 26.609  81.720  -5.042  1.00 37.58  ? 659  ARG   A NH1   1 
ATOM   3441  N  NH2   . ARG   C 3 366 ? 25.957  82.065  -2.873  1.00 44.70  ? 659  ARG   A NH2   1 
ATOM   3442  N  N     . ARG   C 3 367 ? 29.622  76.806  0.338   1.00 36.59  ? 660  ARG   A N     1 
ATOM   3443  C  CA    . ARG   C 3 367 ? 30.294  75.638  -0.219  1.00 37.81  ? 660  ARG   A CA    1 
ATOM   3444  C  C     . ARG   C 3 367 ? 29.515  74.380  0.163   1.00 34.76  ? 660  ARG   A C     1 
ATOM   3445  O  O     . ARG   C 3 367 ? 29.321  73.483  -0.658  1.00 37.25  ? 660  ARG   A O     1 
ATOM   3446  C  CB    . ARG   C 3 367 ? 31.746  75.597  0.277   1.00 38.64  ? 660  ARG   A CB    1 
ATOM   3447  C  CG    . ARG   C 3 367 ? 32.648  74.526  -0.321  1.00 38.54  ? 660  ARG   A CG    1 
ATOM   3448  C  CD    . ARG   C 3 367 ? 32.669  74.485  -1.851  1.00 39.99  ? 660  ARG   A CD    1 
ATOM   3449  N  NE    . ARG   C 3 367 ? 31.840  73.374  -2.271  1.00 39.33  ? 660  ARG   A NE    1 
ATOM   3450  C  CZ    . ARG   C 3 367 ? 31.609  72.989  -3.521  1.00 39.03  ? 660  ARG   A CZ    1 
ATOM   3451  N  NH1   . ARG   C 3 367 ? 32.160  73.634  -4.541  1.00 32.87  ? 660  ARG   A NH1   1 
ATOM   3452  N  NH2   . ARG   C 3 367 ? 30.853  71.911  -3.702  1.00 32.76  ? 660  ARG   A NH2   1 
ATOM   3453  N  N     . ALA   C 3 368 ? 29.043  74.325  1.408   1.00 32.65  ? 661  ALA   A N     1 
ATOM   3454  C  CA    . ALA   C 3 368 ? 28.301  73.163  1.869   1.00 36.63  ? 661  ALA   A CA    1 
ATOM   3455  C  C     . ALA   C 3 368 ? 26.956  73.035  1.134   1.00 36.02  ? 661  ALA   A C     1 
ATOM   3456  O  O     . ALA   C 3 368 ? 26.465  71.922  0.906   1.00 31.74  ? 661  ALA   A O     1 
ATOM   3457  C  CB    . ALA   C 3 368 ? 28.126  73.270  3.361   1.00 39.46  ? 661  ALA   A CB    1 
ATOM   3458  N  N     . ALA   C 3 369 ? 26.364  74.186  0.784   1.00 33.26  ? 662  ALA   A N     1 
ATOM   3459  C  CA    . ALA   C 3 369 ? 25.127  74.244  0.020   1.00 34.17  ? 662  ALA   A CA    1 
ATOM   3460  C  C     . ALA   C 3 369 ? 25.367  73.833  -1.433  1.00 32.39  ? 662  ALA   A C     1 
ATOM   3461  O  O     . ALA   C 3 369 ? 24.507  73.184  -2.027  1.00 33.86  ? 662  ALA   A O     1 
ATOM   3462  C  CB    . ALA   C 3 369 ? 24.541  75.642  0.084   1.00 33.28  ? 662  ALA   A CB    1 
ATOM   3463  N  N     . LYS   C 3 370 ? 26.517  74.231  -2.009  1.00 32.53  ? 663  LYS   A N     1 
ATOM   3464  C  CA    . LYS   C 3 370 ? 26.877  73.825  -3.362  1.00 30.83  ? 663  LYS   A CA    1 
ATOM   3465  C  C     . LYS   C 3 370 ? 26.936  72.305  -3.439  1.00 33.84  ? 663  LYS   A C     1 
ATOM   3466  O  O     . LYS   C 3 370 ? 26.400  71.712  -4.370  1.00 38.11  ? 663  LYS   A O     1 
ATOM   3467  C  CB    . LYS   C 3 370 ? 28.196  74.450  -3.805  1.00 31.50  ? 663  LYS   A CB    1 
ATOM   3468  C  CG    . LYS   C 3 370 ? 28.135  75.946  -4.097  1.00 30.30  ? 663  LYS   A CG    1 
ATOM   3469  C  CD    . LYS   C 3 370 ? 29.509  76.529  -4.330  1.00 29.36  ? 663  LYS   A CD    1 
ATOM   3470  C  CE    . LYS   C 3 370 ? 29.400  77.943  -4.838  1.00 34.34  ? 663  LYS   A CE    1 
ATOM   3471  N  NZ    . LYS   C 3 370 ? 30.728  78.557  -5.000  1.00 36.46  ? 663  LYS   A NZ    1 
ATOM   3472  N  N     . THR   C 3 371 ? 27.493  71.666  -2.407  1.00 32.94  ? 664  THR   A N     1 
ATOM   3473  C  CA    . THR   C 3 371 ? 27.604  70.213  -2.400  1.00 32.66  ? 664  THR   A CA    1 
ATOM   3474  C  C     . THR   C 3 371 ? 26.229  69.543  -2.429  1.00 34.42  ? 664  THR   A C     1 
ATOM   3475  O  O     . THR   C 3 371 ? 26.061  68.518  -3.092  1.00 34.08  ? 664  THR   A O     1 
ATOM   3476  C  CB    . THR   C 3 371 ? 28.467  69.759  -1.217  1.00 32.82  ? 664  THR   A CB    1 
ATOM   3477  O  OG1   . THR   C 3 371 ? 29.762  70.320  -1.407  1.00 33.29  ? 664  THR   A OG1   1 
ATOM   3478  C  CG2   . THR   C 3 371 ? 28.588  68.262  -1.113  1.00 36.02  ? 664  THR   A CG2   1 
ATOM   3479  N  N     . ILE   C 3 372 ? 25.238  70.104  -1.719  1.00 35.53  ? 665  ILE   A N     1 
ATOM   3480  C  CA    . ILE   C 3 372 ? 23.872  69.587  -1.775  1.00 34.18  ? 665  ILE   A CA    1 
ATOM   3481  C  C     . ILE   C 3 372 ? 23.246  69.864  -3.151  1.00 32.34  ? 665  ILE   A C     1 
ATOM   3482  O  O     . ILE   C 3 372 ? 22.667  68.977  -3.758  1.00 33.62  ? 665  ILE   A O     1 
ATOM   3483  C  CB    . ILE   C 3 372 ? 23.006  70.176  -0.639  1.00 35.04  ? 665  ILE   A CB    1 
ATOM   3484  C  CG1   . ILE   C 3 372 ? 23.585  69.875  0.746   1.00 34.93  ? 665  ILE   A CG1   1 
ATOM   3485  C  CG2   . ILE   C 3 372 ? 21.561  69.704  -0.747  1.00 34.90  ? 665  ILE   A CG2   1 
ATOM   3486  C  CD1   . ILE   C 3 372 ? 23.707  68.398  1.033   1.00 39.30  ? 665  ILE   A CD1   1 
ATOM   3487  N  N     . ASN   C 3 373 ? 23.315  71.102  -3.636  1.00 32.91  ? 666  ASN   A N     1 
ATOM   3488  C  CA    . ASN   C 3 373 ? 22.623  71.487  -4.864  1.00 31.64  ? 666  ASN   A CA    1 
ATOM   3489  C  C     . ASN   C 3 373 ? 23.164  70.698  -6.074  1.00 32.31  ? 666  ASN   A C     1 
ATOM   3490  O  O     . ASN   C 3 373 ? 22.410  70.170  -6.884  1.00 35.02  ? 666  ASN   A O     1 
ATOM   3491  C  CB    . ASN   C 3 373 ? 22.759  72.991  -5.109  1.00 29.40  ? 666  ASN   A CB    1 
ATOM   3492  C  CG    . ASN   C 3 373 ? 21.941  73.890  -4.198  1.00 31.64  ? 666  ASN   A CG    1 
ATOM   3493  O  OD1   . ASN   C 3 373 ? 22.214  75.087  -4.090  1.00 38.04  ? 666  ASN   A OD1   1 
ATOM   3494  N  ND2   . ASN   C 3 373 ? 20.925  73.362  -3.548  1.00 28.66  ? 666  ASN   A ND2   1 
ATOM   3495  N  N     . PHE   C 3 374 ? 24.485  70.618  -6.206  1.00 31.64  ? 667  PHE   A N     1 
ATOM   3496  C  CA    . PHE   C 3 374 ? 25.129  69.884  -7.286  1.00 30.11  ? 667  PHE   A CA    1 
ATOM   3497  C  C     . PHE   C 3 374 ? 25.030  68.389  -7.032  1.00 31.31  ? 667  PHE   A C     1 
ATOM   3498  O  O     . PHE   C 3 374 ? 24.857  67.615  -7.967  1.00 35.79  ? 667  PHE   A O     1 
ATOM   3499  C  CB    . PHE   C 3 374 ? 26.602  70.280  -7.399  1.00 28.94  ? 667  PHE   A CB    1 
ATOM   3500  C  CG    . PHE   C 3 374 ? 26.839  71.725  -7.762  1.00 28.50  ? 667  PHE   A CG    1 
ATOM   3501  C  CD1   . PHE   C 3 374 ? 26.124  72.328  -8.792  1.00 28.73  ? 667  PHE   A CD1   1 
ATOM   3502  C  CD2   . PHE   C 3 374 ? 27.813  72.473  -7.106  1.00 30.13  ? 667  PHE   A CD2   1 
ATOM   3503  C  CE1   . PHE   C 3 374 ? 26.345  73.660  -9.123  1.00 31.37  ? 667  PHE   A CE1   1 
ATOM   3504  C  CE2   . PHE   C 3 374 ? 28.064  73.792  -7.466  1.00 28.65  ? 667  PHE   A CE2   1 
ATOM   3505  C  CZ    . PHE   C 3 374 ? 27.313  74.392  -8.451  1.00 31.83  ? 667  PHE   A CZ    1 
ATOM   3506  N  N     . GLY   C 3 375 ? 25.145  68.000  -5.760  1.00 32.18  ? 668  GLY   A N     1 
ATOM   3507  C  CA    . GLY   C 3 375 ? 25.036  66.609  -5.356  1.00 30.71  ? 668  GLY   A CA    1 
ATOM   3508  C  C     . GLY   C 3 375 ? 23.741  65.992  -5.863  1.00 32.33  ? 668  GLY   A C     1 
ATOM   3509  O  O     . GLY   C 3 375 ? 23.760  65.013  -6.597  1.00 31.47  ? 668  GLY   A O     1 
ATOM   3510  N  N     . VAL   C 3 376 ? 22.613  66.575  -5.450  1.00 33.51  ? 669  VAL   A N     1 
ATOM   3511  C  CA    . VAL   C 3 376 ? 21.310  66.048  -5.820  1.00 34.61  ? 669  VAL   A CA    1 
ATOM   3512  C  C     . VAL   C 3 376 ? 21.164  66.021  -7.346  1.00 34.48  ? 669  VAL   A C     1 
ATOM   3513  O  O     . VAL   C 3 376 ? 20.747  65.009  -7.899  1.00 35.64  ? 669  VAL   A O     1 
ATOM   3514  C  CB    . VAL   C 3 376 ? 20.194  66.848  -5.131  1.00 35.05  ? 669  VAL   A CB    1 
ATOM   3515  C  CG1   . VAL   C 3 376 ? 18.826  66.526  -5.703  1.00 36.37  ? 669  VAL   A CG1   1 
ATOM   3516  C  CG2   . VAL   C 3 376 ? 20.230  66.589  -3.628  1.00 40.32  ? 669  VAL   A CG2   1 
ATOM   3517  N  N     . LEU   C 3 377 ? 21.515  67.123  -8.017  1.00 31.11  ? 670  LEU   A N     1 
ATOM   3518  C  CA    . LEU   C 3 377 ? 21.429  67.199  -9.462  1.00 32.92  ? 670  LEU   A CA    1 
ATOM   3519  C  C     . LEU   C 3 377 ? 22.217  66.070  -10.130 1.00 34.71  ? 670  LEU   A C     1 
ATOM   3520  O  O     . LEU   C 3 377 ? 21.694  65.445  -11.054 1.00 36.46  ? 670  LEU   A O     1 
ATOM   3521  C  CB    . LEU   C 3 377 ? 21.937  68.569  -9.902  1.00 35.10  ? 670  LEU   A CB    1 
ATOM   3522  C  CG    . LEU   C 3 377 ? 22.151  68.714  -11.407 1.00 36.85  ? 670  LEU   A CG    1 
ATOM   3523  C  CD1   . LEU   C 3 377 ? 20.859  68.452  -12.160 1.00 36.98  ? 670  LEU   A CD1   1 
ATOM   3524  C  CD2   . LEU   C 3 377 ? 22.707  70.093  -11.735 1.00 34.69  ? 670  LEU   A CD2   1 
ATOM   3525  N  N     . TYR   C 3 378 ? 23.461  65.812  -9.679  1.00 31.30  ? 671  TYR   A N     1 
ATOM   3526  C  CA    . TYR   C 3 378 ? 24.339  64.872  -10.367 1.00 30.98  ? 671  TYR   A CA    1 
ATOM   3527  C  C     . TYR   C 3 378 ? 24.271  63.465  -9.769  1.00 30.97  ? 671  TYR   A C     1 
ATOM   3528  O  O     . TYR   C 3 378 ? 25.080  62.616  -10.123 1.00 31.03  ? 671  TYR   A O     1 
ATOM   3529  C  CB    . TYR   C 3 378 ? 25.765  65.433  -10.474 1.00 31.44  ? 671  TYR   A CB    1 
ATOM   3530  C  CG    . TYR   C 3 378 ? 25.828  66.627  -11.397 1.00 31.06  ? 671  TYR   A CG    1 
ATOM   3531  C  CD1   . TYR   C 3 378 ? 25.469  66.518  -12.734 1.00 32.82  ? 671  TYR   A CD1   1 
ATOM   3532  C  CD2   . TYR   C 3 378 ? 26.137  67.891  -10.924 1.00 32.67  ? 671  TYR   A CD2   1 
ATOM   3533  C  CE1   . TYR   C 3 378 ? 25.453  67.619  -13.580 1.00 31.32  ? 671  TYR   A CE1   1 
ATOM   3534  C  CE2   . TYR   C 3 378 ? 26.115  69.006  -11.751 1.00 30.21  ? 671  TYR   A CE2   1 
ATOM   3535  C  CZ    . TYR   C 3 378 ? 25.777  68.868  -13.083 1.00 29.40  ? 671  TYR   A CZ    1 
ATOM   3536  O  OH    . TYR   C 3 378 ? 25.757  69.962  -13.907 1.00 31.88  ? 671  TYR   A OH    1 
ATOM   3537  N  N     . GLY   C 3 379 ? 23.247  63.176  -8.950  1.00 34.58  ? 672  GLY   A N     1 
ATOM   3538  C  CA    . GLY   C 3 379 ? 22.818  61.800  -8.712  1.00 34.52  ? 672  GLY   A CA    1 
ATOM   3539  C  C     . GLY   C 3 379 ? 23.292  61.209  -7.383  1.00 33.90  ? 672  GLY   A C     1 
ATOM   3540  O  O     . GLY   C 3 379 ? 23.393  59.998  -7.243  1.00 35.29  ? 672  GLY   A O     1 
ATOM   3541  N  N     . MET   C 3 380 ? 23.557  62.070  -6.401  1.00 37.64  ? 673  MET   A N     1 
ATOM   3542  C  CA    . MET   C 3 380 ? 23.868  61.649  -5.050  1.00 38.14  ? 673  MET   A CA    1 
ATOM   3543  C  C     . MET   C 3 380 ? 22.710  60.828  -4.488  1.00 39.32  ? 673  MET   A C     1 
ATOM   3544  O  O     . MET   C 3 380 ? 21.548  61.232  -4.585  1.00 39.99  ? 673  MET   A O     1 
ATOM   3545  C  CB    . MET   C 3 380 ? 24.085  62.882  -4.167  1.00 41.60  ? 673  MET   A CB    1 
ATOM   3546  C  CG    . MET   C 3 380 ? 24.230  62.545  -2.689  1.00 40.91  ? 673  MET   A CG    1 
ATOM   3547  S  SD    . MET   C 3 380 ? 24.645  63.970  -1.683  1.00 44.62  ? 673  MET   A SD    1 
ATOM   3548  C  CE    . MET   C 3 380 ? 26.260  64.438  -2.306  1.00 40.70  ? 673  MET   A CE    1 
ATOM   3549  N  N     . SER   C 3 381 ? 23.051  59.698  -3.860  1.00 40.82  ? 674  SER   A N     1 
ATOM   3550  C  CA    . SER   C 3 381 ? 22.071  58.787  -3.283  1.00 42.70  ? 674  SER   A CA    1 
ATOM   3551  C  C     . SER   C 3 381 ? 21.377  59.437  -2.082  1.00 43.82  ? 674  SER   A C     1 
ATOM   3552  O  O     . SER   C 3 381 ? 21.930  60.337  -1.446  1.00 40.13  ? 674  SER   A O     1 
ATOM   3553  C  CB    . SER   C 3 381 ? 22.728  57.485  -2.875  1.00 44.58  ? 674  SER   A CB    1 
ATOM   3554  O  OG    . SER   C 3 381 ? 23.696  57.697  -1.845  1.00 47.20  ? 674  SER   A OG    1 
ATOM   3555  N  N     . ALA   C 3 382 ? 20.161  58.952  -1.772  1.00 46.33  ? 675  ALA   A N     1 
ATOM   3556  C  CA    . ALA   C 3 382 ? 19.404  59.384  -0.602  1.00 47.68  ? 675  ALA   A CA    1 
ATOM   3557  C  C     . ALA   C 3 382 ? 20.172  59.079  0.687   1.00 49.26  ? 675  ALA   A C     1 
ATOM   3558  O  O     . ALA   C 3 382 ? 20.254  59.932  1.572   1.00 51.15  ? 675  ALA   A O     1 
ATOM   3559  C  CB    . ALA   C 3 382 ? 18.038  58.739  -0.603  1.00 46.63  ? 675  ALA   A CB    1 
ATOM   3560  N  N     . HIS   C 3 383 ? 20.757  57.877  0.769   1.00 54.13  ? 676  HIS   A N     1 
ATOM   3561  C  CA    . HIS   C 3 383 ? 21.585  57.498  1.904   1.00 61.26  ? 676  HIS   A CA    1 
ATOM   3562  C  C     . HIS   C 3 383 ? 22.564  58.626  2.220   1.00 59.78  ? 676  HIS   A C     1 
ATOM   3563  O  O     . HIS   C 3 383 ? 22.525  59.160  3.326   1.00 58.66  ? 676  HIS   A O     1 
ATOM   3564  C  CB    . HIS   C 3 383 ? 22.296  56.156  1.642   1.00 75.81  ? 676  HIS   A CB    1 
ATOM   3565  C  CG    . HIS   C 3 383 ? 23.134  55.627  2.776   1.00 89.47  ? 676  HIS   A CG    1 
ATOM   3566  N  ND1   . HIS   C 3 383 ? 22.721  55.574  4.093   1.00 91.97  ? 676  HIS   A ND1   1 
ATOM   3567  C  CD2   . HIS   C 3 383 ? 24.401  55.118  2.745   1.00 94.33  ? 676  HIS   A CD2   1 
ATOM   3568  C  CE1   . HIS   C 3 383 ? 23.693  55.054  4.840   1.00 93.29  ? 676  HIS   A CE1   1 
ATOM   3569  N  NE2   . HIS   C 3 383 ? 24.747  54.762  4.022   1.00 94.50  ? 676  HIS   A NE2   1 
ATOM   3570  N  N     . ARG   C 3 384 ? 23.396  59.018  1.236   1.00 58.74  ? 677  ARG   A N     1 
ATOM   3571  C  CA    . ARG   C 3 384 ? 24.468  59.980  1.467   1.00 54.07  ? 677  ARG   A CA    1 
ATOM   3572  C  C     . ARG   C 3 384 ? 23.893  61.354  1.793   1.00 51.74  ? 677  ARG   A C     1 
ATOM   3573  O  O     . ARG   C 3 384 ? 24.471  62.119  2.569   1.00 51.16  ? 677  ARG   A O     1 
ATOM   3574  C  CB    . ARG   C 3 384 ? 25.397  60.069  0.250   1.00 58.13  ? 677  ARG   A CB    1 
ATOM   3575  C  CG    . ARG   C 3 384 ? 26.542  61.069  0.389   1.00 64.21  ? 677  ARG   A CG    1 
ATOM   3576  C  CD    . ARG   C 3 384 ? 27.539  60.770  1.498   1.00 70.33  ? 677  ARG   A CD    1 
ATOM   3577  N  NE    . ARG   C 3 384 ? 28.110  59.431  1.368   1.00 82.84  ? 677  ARG   A NE    1 
ATOM   3578  C  CZ    . ARG   C 3 384 ? 28.869  59.013  0.352   1.00 87.13  ? 677  ARG   A CZ    1 
ATOM   3579  N  NH1   . ARG   C 3 384 ? 29.748  59.829  -0.207  1.00 83.18  ? 677  ARG   A NH1   1 
ATOM   3580  N  NH2   . ARG   C 3 384 ? 28.779  57.763  -0.078  1.00 89.92  ? 677  ARG   A NH2   1 
ATOM   3581  N  N     . LEU   C 3 385 ? 22.757  61.675  1.172   1.00 49.57  ? 678  LEU   A N     1 
ATOM   3582  C  CA    . LEU   C 3 385 ? 22.145  62.980  1.355   1.00 53.29  ? 678  LEU   A CA    1 
ATOM   3583  C  C     . LEU   C 3 385 ? 21.506  63.088  2.748   1.00 49.55  ? 678  LEU   A C     1 
ATOM   3584  O  O     . LEU   C 3 385 ? 21.492  64.165  3.337   1.00 44.88  ? 678  LEU   A O     1 
ATOM   3585  C  CB    . LEU   C 3 385 ? 21.121  63.163  0.234   1.00 52.06  ? 678  LEU   A CB    1 
ATOM   3586  C  CG    . LEU   C 3 385 ? 20.337  64.465  0.277   1.00 51.20  ? 678  LEU   A CG    1 
ATOM   3587  C  CD1   . LEU   C 3 385 ? 21.241  65.636  -0.079  1.00 51.09  ? 678  LEU   A CD1   1 
ATOM   3588  C  CD2   . LEU   C 3 385 ? 19.131  64.372  -0.655  1.00 55.38  ? 678  LEU   A CD2   1 
ATOM   3589  N  N     . SER   C 3 386 ? 20.986  61.970  3.270   1.00 48.59  ? 679  SER   A N     1 
ATOM   3590  C  CA    . SER   C 3 386 ? 20.456  61.923  4.626   1.00 57.18  ? 679  SER   A CA    1 
ATOM   3591  C  C     . SER   C 3 386 ? 21.564  62.180  5.651   1.00 57.91  ? 679  SER   A C     1 
ATOM   3592  O  O     . SER   C 3 386 ? 21.354  62.926  6.606   1.00 57.60  ? 679  SER   A O     1 
ATOM   3593  C  CB    . SER   C 3 386 ? 19.751  60.618  4.890   1.00 61.81  ? 679  SER   A CB    1 
ATOM   3594  O  OG    . SER   C 3 386 ? 20.674  59.568  5.133   1.00 68.28  ? 679  SER   A OG    1 
ATOM   3595  N  N     . GLN   C 3 387 ? 22.756  61.611  5.425   1.00 58.13  ? 680  GLN   A N     1 
ATOM   3596  C  CA    . GLN   C 3 387 ? 23.889  61.829  6.316   1.00 61.95  ? 680  GLN   A CA    1 
ATOM   3597  C  C     . GLN   C 3 387 ? 24.346  63.285  6.276   1.00 63.38  ? 680  GLN   A C     1 
ATOM   3598  O  O     . GLN   C 3 387 ? 24.760  63.840  7.287   1.00 72.78  ? 680  GLN   A O     1 
ATOM   3599  C  CB    . GLN   C 3 387 ? 25.081  60.949  5.937   1.00 68.84  ? 680  GLN   A CB    1 
ATOM   3600  C  CG    . GLN   C 3 387 ? 24.797  59.453  5.983   1.00 76.99  ? 680  GLN   A CG    1 
ATOM   3601  C  CD    . GLN   C 3 387 ? 26.052  58.651  5.732   1.00 92.16  ? 680  GLN   A CD    1 
ATOM   3602  O  OE1   . GLN   C 3 387 ? 26.797  58.906  4.784   1.00 100.85 ? 680  GLN   A OE1   1 
ATOM   3603  N  NE2   . GLN   C 3 387 ? 26.313  57.692  6.608   1.00 94.74  ? 680  GLN   A NE2   1 
ATOM   3604  N  N     . LYS   C 3 388 ? 24.258  63.908  5.103   1.00 65.56  ? 681  LYS   A N     1 
ATOM   3605  C  CA    . LYS   C 3 388 ? 24.867  65.207  4.866   1.00 64.66  ? 681  LYS   A CA    1 
ATOM   3606  C  C     . LYS   C 3 388 ? 23.932  66.329  5.332   1.00 60.67  ? 681  LYS   A C     1 
ATOM   3607  O  O     . LYS   C 3 388 ? 24.376  67.432  5.657   1.00 62.44  ? 681  LYS   A O     1 
ATOM   3608  C  CB    . LYS   C 3 388 ? 25.225  65.281  3.377   1.00 66.81  ? 681  LYS   A CB    1 
ATOM   3609  C  CG    . LYS   C 3 388 ? 26.608  65.823  3.052   1.00 68.07  ? 681  LYS   A CG    1 
ATOM   3610  C  CD    . LYS   C 3 388 ? 27.202  65.184  1.817   1.00 70.28  ? 681  LYS   A CD    1 
ATOM   3611  C  CE    . LYS   C 3 388 ? 28.597  65.684  1.505   1.00 74.80  ? 681  LYS   A CE    1 
ATOM   3612  N  NZ    . LYS   C 3 388 ? 29.493  65.578  2.681   1.00 75.04  ? 681  LYS   A NZ    1 
ATOM   3613  N  N     . LEU   C 3 389 ? 22.625  66.048  5.341   1.00 60.78  ? 682  LEU   A N     1 
ATOM   3614  C  CA    . LEU   C 3 389 ? 21.619  66.976  5.845   1.00 61.27  ? 682  LEU   A CA    1 
ATOM   3615  C  C     . LEU   C 3 389 ? 21.129  66.567  7.239   1.00 62.19  ? 682  LEU   A C     1 
ATOM   3616  O  O     . LEU   C 3 389 ? 20.347  67.299  7.846   1.00 64.70  ? 682  LEU   A O     1 
ATOM   3617  C  CB    . LEU   C 3 389 ? 20.433  66.978  4.875   1.00 54.80  ? 682  LEU   A CB    1 
ATOM   3618  C  CG    . LEU   C 3 389 ? 20.664  67.651  3.531   1.00 50.73  ? 682  LEU   A CG    1 
ATOM   3619  C  CD1   . LEU   C 3 389 ? 19.456  67.450  2.632   1.00 49.80  ? 682  LEU   A CD1   1 
ATOM   3620  C  CD2   . LEU   C 3 389 ? 20.954  69.130  3.716   1.00 50.51  ? 682  LEU   A CD2   1 
ATOM   3621  N  N     . ALA   C 3 390 ? 21.537  65.372  7.701   1.00 64.02  ? 683  ALA   A N     1 
ATOM   3622  C  CA    . ALA   C 3 390 ? 21.124  64.825  8.987   1.00 69.35  ? 683  ALA   A CA    1 
ATOM   3623  C  C     . ALA   C 3 390 ? 19.598  64.771  9.057   1.00 67.95  ? 683  ALA   A C     1 
ATOM   3624  O  O     . ALA   C 3 390 ? 18.989  65.401  9.918   1.00 74.16  ? 683  ALA   A O     1 
ATOM   3625  C  CB    . ALA   C 3 390 ? 21.720  65.633  10.124  1.00 67.34  ? 683  ALA   A CB    1 
ATOM   3626  N  N     . ILE   C 3 391 ? 19.000  64.024  8.120   1.00 61.21  ? 684  ILE   A N     1 
ATOM   3627  C  CA    . ILE   C 3 391 ? 17.561  63.831  8.061   1.00 57.13  ? 684  ILE   A CA    1 
ATOM   3628  C  C     . ILE   C 3 391 ? 17.304  62.353  7.796   1.00 56.50  ? 684  ILE   A C     1 
ATOM   3629  O  O     . ILE   C 3 391 ? 18.203  61.627  7.373   1.00 59.06  ? 684  ILE   A O     1 
ATOM   3630  C  CB    . ILE   C 3 391 ? 16.902  64.734  6.993   1.00 61.05  ? 684  ILE   A CB    1 
ATOM   3631  C  CG1   . ILE   C 3 391 ? 17.412  64.411  5.582   1.00 65.44  ? 684  ILE   A CG1   1 
ATOM   3632  C  CG2   . ILE   C 3 391 ? 17.069  66.210  7.334   1.00 59.16  ? 684  ILE   A CG2   1 
ATOM   3633  C  CD1   . ILE   C 3 391 ? 16.900  65.338  4.499   1.00 62.93  ? 684  ILE   A CD1   1 
ATOM   3634  N  N     . PRO   C 3 392 ? 16.085  61.841  8.067   1.00 53.98  ? 685  PRO   A N     1 
ATOM   3635  C  CA    . PRO   C 3 392 ? 15.766  60.453  7.741   1.00 54.48  ? 685  PRO   A CA    1 
ATOM   3636  C  C     . PRO   C 3 392 ? 15.856  60.159  6.240   1.00 58.84  ? 685  PRO   A C     1 
ATOM   3637  O  O     . PRO   C 3 392 ? 15.627  61.029  5.396   1.00 57.67  ? 685  PRO   A O     1 
ATOM   3638  C  CB    . PRO   C 3 392 ? 14.329  60.242  8.250   1.00 52.67  ? 685  PRO   A CB    1 
ATOM   3639  C  CG    . PRO   C 3 392 ? 14.046  61.421  9.168   1.00 54.39  ? 685  PRO   A CG    1 
ATOM   3640  C  CD    . PRO   C 3 392 ? 14.989  62.537  8.761   1.00 55.91  ? 685  PRO   A CD    1 
ATOM   3641  N  N     . TYR   C 3 393 ? 16.173  58.898  5.941   1.00 54.96  ? 686  TYR   A N     1 
ATOM   3642  C  CA    . TYR   C 3 393 ? 16.276  58.388  4.594   1.00 57.64  ? 686  TYR   A CA    1 
ATOM   3643  C  C     . TYR   C 3 393 ? 15.118  58.883  3.729   1.00 63.95  ? 686  TYR   A C     1 
ATOM   3644  O  O     . TYR   C 3 393 ? 15.345  59.472  2.676   1.00 66.76  ? 686  TYR   A O     1 
ATOM   3645  C  CB    . TYR   C 3 393 ? 16.298  56.861  4.649   1.00 61.09  ? 686  TYR   A CB    1 
ATOM   3646  C  CG    . TYR   C 3 393 ? 16.520  56.199  3.317   1.00 63.65  ? 686  TYR   A CG    1 
ATOM   3647  C  CD1   . TYR   C 3 393 ? 17.781  56.172  2.743   1.00 66.17  ? 686  TYR   A CD1   1 
ATOM   3648  C  CD2   . TYR   C 3 393 ? 15.470  55.630  2.614   1.00 62.18  ? 686  TYR   A CD2   1 
ATOM   3649  C  CE1   . TYR   C 3 393 ? 18.000  55.569  1.513   1.00 65.94  ? 686  TYR   A CE1   1 
ATOM   3650  C  CE2   . TYR   C 3 393 ? 15.671  55.033  1.379   1.00 66.39  ? 686  TYR   A CE2   1 
ATOM   3651  C  CZ    . TYR   C 3 393 ? 16.941  55.006  0.826   1.00 63.97  ? 686  TYR   A CZ    1 
ATOM   3652  O  OH    . TYR   C 3 393 ? 17.169  54.417  -0.392  1.00 73.34  ? 686  TYR   A OH    1 
ATOM   3653  N  N     . GLU   C 3 394 ? 13.881  58.642  4.186   1.00 70.59  ? 687  GLU   A N     1 
ATOM   3654  C  CA    . GLU   C 3 394 ? 12.677  58.856  3.389   1.00 69.76  ? 687  GLU   A CA    1 
ATOM   3655  C  C     . GLU   C 3 394 ? 12.536  60.333  3.022   1.00 61.28  ? 687  GLU   A C     1 
ATOM   3656  O  O     . GLU   C 3 394 ? 11.986  60.667  1.972   1.00 54.47  ? 687  GLU   A O     1 
ATOM   3657  C  CB    . GLU   C 3 394 ? 11.416  58.411  4.145   1.00 76.44  ? 687  GLU   A CB    1 
ATOM   3658  C  CG    . GLU   C 3 394 ? 11.296  56.904  4.387   1.00 83.30  ? 687  GLU   A CG    1 
ATOM   3659  C  CD    . GLU   C 3 394 ? 12.128  56.332  5.532   1.00 85.09  ? 687  GLU   A CD    1 
ATOM   3660  O  OE1   . GLU   C 3 394 ? 12.206  56.984  6.604   1.00 87.98  ? 687  GLU   A OE1   1 
ATOM   3661  O  OE2   . GLU   C 3 394 ? 12.682  55.225  5.364   1.00 72.74  ? 687  GLU   A OE2   1 
ATOM   3662  N  N     . GLU   C 3 395 ? 13.021  61.204  3.911   1.00 55.08  ? 688  GLU   A N     1 
ATOM   3663  C  CA    . GLU   C 3 395 ? 12.922  62.642  3.742   1.00 60.06  ? 688  GLU   A CA    1 
ATOM   3664  C  C     . GLU   C 3 395 ? 13.970  63.120  2.734   1.00 57.42  ? 688  GLU   A C     1 
ATOM   3665  O  O     . GLU   C 3 395 ? 13.804  64.153  2.093   1.00 60.37  ? 688  GLU   A O     1 
ATOM   3666  C  CB    . GLU   C 3 395 ? 13.102  63.287  5.115   1.00 68.29  ? 688  GLU   A CB    1 
ATOM   3667  C  CG    . GLU   C 3 395 ? 12.531  64.685  5.223   1.00 79.68  ? 688  GLU   A CG    1 
ATOM   3668  C  CD    . GLU   C 3 395 ? 12.784  65.350  6.567   1.00 85.62  ? 688  GLU   A CD    1 
ATOM   3669  O  OE1   . GLU   C 3 395 ? 12.421  64.743  7.612   1.00 82.51  ? 688  GLU   A OE1   1 
ATOM   3670  O  OE2   . GLU   C 3 395 ? 13.340  66.471  6.569   1.00 91.27  ? 688  GLU   A OE2   1 
ATOM   3671  N  N     . ALA   C 3 396 ? 15.063  62.360  2.617   1.00 55.06  ? 689  ALA   A N     1 
ATOM   3672  C  CA    . ALA   C 3 396 ? 16.094  62.609  1.628   1.00 48.85  ? 689  ALA   A CA    1 
ATOM   3673  C  C     . ALA   C 3 396 ? 15.596  62.198  0.245   1.00 47.74  ? 689  ALA   A C     1 
ATOM   3674  O  O     . ALA   C 3 396 ? 15.816  62.939  -0.710  1.00 45.08  ? 689  ALA   A O     1 
ATOM   3675  C  CB    . ALA   C 3 396 ? 17.364  61.880  1.995   1.00 50.44  ? 689  ALA   A CB    1 
ATOM   3676  N  N     A GLN   C 3 397 ? 14.956  61.016  0.165   0.50 46.14  ? 690  GLN   A N     1 
ATOM   3677  N  N     B GLN   C 3 397 ? 14.947  61.031  0.144   0.50 46.25  ? 690  GLN   A N     1 
ATOM   3678  C  CA    A GLN   C 3 397 ? 14.298  60.517  -1.038  0.50 48.25  ? 690  GLN   A CA    1 
ATOM   3679  C  CA    B GLN   C 3 397 ? 14.420  60.607  -1.144  0.50 48.37  ? 690  GLN   A CA    1 
ATOM   3680  C  C     A GLN   C 3 397 ? 13.325  61.564  -1.570  0.50 47.94  ? 690  GLN   A C     1 
ATOM   3681  C  C     B GLN   C 3 397 ? 13.321  61.570  -1.588  0.50 48.05  ? 690  GLN   A C     1 
ATOM   3682  O  O     A GLN   C 3 397 ? 13.235  61.799  -2.774  0.50 49.68  ? 690  GLN   A O     1 
ATOM   3683  O  O     B GLN   C 3 397 ? 13.200  61.809  -2.783  0.50 49.88  ? 690  GLN   A O     1 
ATOM   3684  C  CB    A GLN   C 3 397 ? 13.479  59.247  -0.760  0.50 46.03  ? 690  GLN   A CB    1 
ATOM   3685  C  CB    B GLN   C 3 397 ? 13.970  59.144  -1.152  0.50 46.47  ? 690  GLN   A CB    1 
ATOM   3686  C  CG    A GLN   C 3 397 ? 14.277  58.053  -0.245  0.50 46.56  ? 690  GLN   A CG    1 
ATOM   3687  C  CG    B GLN   C 3 397 ? 13.630  58.610  -2.548  0.50 46.13  ? 690  GLN   A CG    1 
ATOM   3688  C  CD    A GLN   C 3 397 ? 13.503  56.751  -0.281  0.50 45.40  ? 690  GLN   A CD    1 
ATOM   3689  C  CD    B GLN   C 3 397 ? 14.614  58.928  -3.656  0.50 43.79  ? 690  GLN   A CD    1 
ATOM   3690  O  OE1   A GLN   C 3 397 ? 13.752  55.883  -1.117  0.50 43.97  ? 690  GLN   A OE1   1 
ATOM   3691  O  OE1   B GLN   C 3 397 ? 15.769  58.501  -3.654  0.50 39.43  ? 690  GLN   A OE1   1 
ATOM   3692  N  NE2   A GLN   C 3 397 ? 12.552  56.597  0.625   0.50 40.36  ? 690  GLN   A NE2   1 
ATOM   3693  N  NE2   B GLN   C 3 397 ? 14.140  59.661  -4.652  0.50 41.14  ? 690  GLN   A NE2   1 
ATOM   3694  N  N     . ALA   C 3 398 ? 12.566  62.144  -0.638  1.00 45.59  ? 691  ALA   A N     1 
ATOM   3695  C  CA    . ALA   C 3 398 ? 11.536  63.121  -0.951  1.00 45.16  ? 691  ALA   A CA    1 
ATOM   3696  C  C     . ALA   C 3 398 ? 12.177  64.408  -1.455  1.00 42.23  ? 691  ALA   A C     1 
ATOM   3697  O  O     . ALA   C 3 398 ? 11.647  65.046  -2.355  1.00 44.80  ? 691  ALA   A O     1 
ATOM   3698  C  CB    . ALA   C 3 398 ? 10.684  63.392  0.275   1.00 45.85  ? 691  ALA   A CB    1 
ATOM   3699  N  N     . PHE   C 3 399 ? 13.292  64.795  -0.830  1.00 40.74  ? 692  PHE   A N     1 
ATOM   3700  C  CA    . PHE   C 3 399 ? 14.039  65.980  -1.227  1.00 41.43  ? 692  PHE   A CA    1 
ATOM   3701  C  C     . PHE   C 3 399 ? 14.455  65.889  -2.697  1.00 40.52  ? 692  PHE   A C     1 
ATOM   3702  O  O     . PHE   C 3 399 ? 14.262  66.834  -3.458  1.00 38.91  ? 692  PHE   A O     1 
ATOM   3703  C  CB    . PHE   C 3 399 ? 15.287  66.149  -0.353  1.00 40.72  ? 692  PHE   A CB    1 
ATOM   3704  C  CG    . PHE   C 3 399 ? 16.074  67.401  -0.659  1.00 41.79  ? 692  PHE   A CG    1 
ATOM   3705  C  CD1   . PHE   C 3 399 ? 17.056  67.407  -1.638  1.00 37.87  ? 692  PHE   A CD1   1 
ATOM   3706  C  CD2   . PHE   C 3 399 ? 15.794  68.589  0.003   1.00 42.74  ? 692  PHE   A CD2   1 
ATOM   3707  C  CE1   . PHE   C 3 399 ? 17.758  68.565  -1.933  1.00 39.73  ? 692  PHE   A CE1   1 
ATOM   3708  C  CE2   . PHE   C 3 399 ? 16.499  69.746  -0.297  1.00 42.50  ? 692  PHE   A CE2   1 
ATOM   3709  C  CZ    . PHE   C 3 399 ? 17.472  69.734  -1.270  1.00 41.04  ? 692  PHE   A CZ    1 
ATOM   3710  N  N     . ILE   C 3 400 ? 15.049  64.746  -3.054  1.00 36.87  ? 693  ILE   A N     1 
ATOM   3711  C  CA    . ILE   C 3 400 ? 15.477  64.445  -4.408  1.00 39.46  ? 693  ILE   A CA    1 
ATOM   3712  C  C     . ILE   C 3 400 ? 14.294  64.570  -5.371  1.00 40.23  ? 693  ILE   A C     1 
ATOM   3713  O  O     . ILE   C 3 400 ? 14.386  65.234  -6.399  1.00 38.45  ? 693  ILE   A O     1 
ATOM   3714  C  CB    . ILE   C 3 400 ? 16.144  63.053  -4.432  1.00 35.73  ? 693  ILE   A CB    1 
ATOM   3715  C  CG1   . ILE   C 3 400 ? 17.436  63.064  -3.619  1.00 34.80  ? 693  ILE   A CG1   1 
ATOM   3716  C  CG2   . ILE   C 3 400 ? 16.397  62.559  -5.851  1.00 38.71  ? 693  ILE   A CG2   1 
ATOM   3717  C  CD1   . ILE   C 3 400 ? 18.005  61.677  -3.341  1.00 34.59  ? 693  ILE   A CD1   1 
ATOM   3718  N  N     . GLU   C 3 401 ? 13.160  63.967  -5.040  1.00 48.13  ? 694  GLU   A N     1 
ATOM   3719  C  CA    . GLU   C 3 401 ? 12.003  63.957  -5.974  1.00 46.37  ? 694  GLU   A CA    1 
ATOM   3720  C  C     . GLU   C 3 401 ? 11.376  65.351  -6.101  1.00 45.89  ? 694  GLU   A C     1 
ATOM   3721  O  O     . GLU   C 3 401 ? 10.862  65.652  -7.180  1.00 44.31  ? 694  GLU   A O     1 
ATOM   3722  C  CB    . GLU   C 3 401 ? 11.008  62.891  -5.518  1.00 52.08  ? 694  GLU   A CB    1 
ATOM   3723  C  CG    . GLU   C 3 401 ? 11.193  61.568  -6.230  1.00 61.25  ? 694  GLU   A CG    1 
ATOM   3724  C  CD    . GLU   C 3 401 ? 11.325  61.697  -7.737  1.00 74.42  ? 694  GLU   A CD    1 
ATOM   3725  O  OE1   . GLU   C 3 401 ? 10.301  61.952  -8.396  1.00 73.78  ? 694  GLU   A OE1   1 
ATOM   3726  O  OE2   . GLU   C 3 401 ? 12.453  61.551  -8.246  1.00 81.53  ? 694  GLU   A OE2   1 
ATOM   3727  N  N     . ARG   C 3 402 ? 11.437  66.161  -5.048  1.00 41.44  ? 695  ARG   A N     1 
ATOM   3728  C  CA    . ARG   C 3 402 ? 10.898  67.543  -5.091  1.00 43.57  ? 695  ARG   A CA    1 
ATOM   3729  C  C     . ARG   C 3 402 ? 11.749  68.410  -6.019  1.00 44.04  ? 695  ARG   A C     1 
ATOM   3730  O  O     . ARG   C 3 402 ? 11.177  69.275  -6.691  1.00 46.59  ? 695  ARG   A O     1 
ATOM   3731  C  CB    . ARG   C 3 402 ? 10.850  68.139  -3.684  1.00 46.48  ? 695  ARG   A CB    1 
ATOM   3732  C  CG    . ARG   C 3 402 ? 9.449   68.425  -3.169  1.00 51.35  ? 695  ARG   A CG    1 
ATOM   3733  C  CD    . ARG   C 3 402 ? 9.367   68.365  -1.657  1.00 53.57  ? 695  ARG   A CD    1 
ATOM   3734  N  NE    . ARG   C 3 402 ? 10.643  68.632  -1.014  1.00 59.66  ? 695  ARG   A NE    1 
ATOM   3735  C  CZ    . ARG   C 3 402 ? 11.046  68.063  0.114   1.00 62.30  ? 695  ARG   A CZ    1 
ATOM   3736  N  NH1   . ARG   C 3 402 ? 10.371  67.048  0.620   1.00 64.82  ? 695  ARG   A NH1   1 
ATOM   3737  N  NH2   . ARG   C 3 402 ? 12.122  68.513  0.735   1.00 65.58  ? 695  ARG   A NH2   1 
ATOM   3738  N  N     . TYR   C 3 403 ? 13.061  68.176  -6.049  1.00 43.87  ? 696  TYR   A N     1 
ATOM   3739  C  CA    . TYR   C 3 403 ? 13.959  68.963  -6.927  1.00 42.84  ? 696  TYR   A CA    1 
ATOM   3740  C  C     . TYR   C 3 403 ? 13.573  68.712  -8.380  1.00 40.40  ? 696  TYR   A C     1 
ATOM   3741  O  O     . TYR   C 3 403 ? 13.407  69.670  -9.131  1.00 40.72  ? 696  TYR   A O     1 
ATOM   3742  C  CB    . TYR   C 3 403 ? 15.432  68.617  -6.709  1.00 43.38  ? 696  TYR   A CB    1 
ATOM   3743  C  CG    . TYR   C 3 403 ? 16.354  69.195  -7.749  1.00 40.53  ? 696  TYR   A CG    1 
ATOM   3744  C  CD1   . TYR   C 3 403 ? 16.692  70.536  -7.728  1.00 40.77  ? 696  TYR   A CD1   1 
ATOM   3745  C  CD2   . TYR   C 3 403 ? 16.873  68.411  -8.763  1.00 39.84  ? 696  TYR   A CD2   1 
ATOM   3746  C  CE1   . TYR   C 3 403 ? 17.530  71.083  -8.681  1.00 40.33  ? 696  TYR   A CE1   1 
ATOM   3747  C  CE2   . TYR   C 3 403 ? 17.712  68.942  -9.727  1.00 41.18  ? 696  TYR   A CE2   1 
ATOM   3748  C  CZ    . TYR   C 3 403 ? 18.043  70.284  -9.684  1.00 42.96  ? 696  TYR   A CZ    1 
ATOM   3749  O  OH    . TYR   C 3 403 ? 18.872  70.833  -10.624 1.00 41.82  ? 696  TYR   A OH    1 
ATOM   3750  N  N     . PHE   C 3 404 ? 13.415  67.445  -8.735  1.00 40.58  ? 697  PHE   A N     1 
ATOM   3751  C  CA    . PHE   C 3 404 ? 13.101  67.116  -10.118 1.00 43.39  ? 697  PHE   A CA    1 
ATOM   3752  C  C     . PHE   C 3 404 ? 11.640  67.390  -10.498 1.00 50.02  ? 697  PHE   A C     1 
ATOM   3753  O  O     . PHE   C 3 404 ? 11.331  67.466  -11.685 1.00 54.83  ? 697  PHE   A O     1 
ATOM   3754  C  CB    . PHE   C 3 404 ? 13.517  65.670  -10.370 1.00 42.18  ? 697  PHE   A CB    1 
ATOM   3755  C  CG    . PHE   C 3 404 ? 15.018  65.492  -10.404 1.00 42.84  ? 697  PHE   A CG    1 
ATOM   3756  C  CD1   . PHE   C 3 404 ? 15.782  66.111  -11.391 1.00 41.56  ? 697  PHE   A CD1   1 
ATOM   3757  C  CD2   . PHE   C 3 404 ? 15.678  64.738  -9.443  1.00 42.93  ? 697  PHE   A CD2   1 
ATOM   3758  C  CE1   . PHE   C 3 404 ? 17.157  65.946  -11.440 1.00 40.30  ? 697  PHE   A CE1   1 
ATOM   3759  C  CE2   . PHE   C 3 404 ? 17.060  64.596  -9.476  1.00 43.25  ? 697  PHE   A CE2   1 
ATOM   3760  C  CZ    . PHE   C 3 404 ? 17.795  65.191  -10.480 1.00 42.68  ? 697  PHE   A CZ    1 
ATOM   3761  N  N     A GLN   C 3 405 ? 10.759  67.518  -9.490  0.50 53.40  ? 698  GLN   A N     1 
ATOM   3762  N  N     B GLN   C 3 405 ? 10.762  67.523  -9.497  0.50 53.08  ? 698  GLN   A N     1 
ATOM   3763  C  CA    A GLN   C 3 405 ? 9.376   67.959  -9.655  0.50 51.63  ? 698  GLN   A CA    1 
ATOM   3764  C  CA    B GLN   C 3 405 ? 9.390   67.951  -9.719  0.50 51.02  ? 698  GLN   A CA    1 
ATOM   3765  C  C     A GLN   C 3 405 ? 9.364   69.460  -9.940  0.50 50.32  ? 698  GLN   A C     1 
ATOM   3766  C  C     B GLN   C 3 405 ? 9.364   69.463  -9.947  0.50 50.03  ? 698  GLN   A C     1 
ATOM   3767  O  O     A GLN   C 3 405 ? 8.569   69.934  -10.748 0.50 52.01  ? 698  GLN   A O     1 
ATOM   3768  O  O     B GLN   C 3 405 ? 8.565   69.947  -10.744 0.50 51.72  ? 698  GLN   A O     1 
ATOM   3769  C  CB    A GLN   C 3 405 ? 8.555   67.645  -8.390  0.50 53.63  ? 698  GLN   A CB    1 
ATOM   3770  C  CB    B GLN   C 3 405 ? 8.497   67.535  -8.546  0.50 52.86  ? 698  GLN   A CB    1 
ATOM   3771  C  CG    A GLN   C 3 405 ? 7.084   68.068  -8.427  0.50 54.59  ? 698  GLN   A CG    1 
ATOM   3772  C  CG    B GLN   C 3 405 ? 8.326   66.021  -8.407  0.50 53.73  ? 698  GLN   A CG    1 
ATOM   3773  C  CD    A GLN   C 3 405 ? 6.381   68.028  -7.085  0.50 55.98  ? 698  GLN   A CD    1 
ATOM   3774  C  CD    B GLN   C 3 405 ? 7.235   65.397  -9.244  0.50 51.26  ? 698  GLN   A CD    1 
ATOM   3775  O  OE1   A GLN   C 3 405 ? 6.978   67.776  -6.037  0.50 51.51  ? 698  GLN   A OE1   1 
ATOM   3776  O  OE1   B GLN   C 3 405 ? 6.759   64.308  -8.940  0.50 49.14  ? 698  GLN   A OE1   1 
ATOM   3777  N  NE2   A GLN   C 3 405 ? 5.087   68.309  -7.102  0.50 50.43  ? 698  GLN   A NE2   1 
ATOM   3778  N  NE2   B GLN   C 3 405 ? 6.819   66.077  -10.299 0.50 49.62  ? 698  GLN   A NE2   1 
ATOM   3779  N  N     . SER   C 3 406 ? 10.231  70.204  -9.242  1.00 48.99  ? 699  SER   A N     1 
ATOM   3780  C  CA    . SER   C 3 406 ? 10.395  71.638  -9.461  1.00 48.89  ? 699  SER   A CA    1 
ATOM   3781  C  C     . SER   C 3 406 ? 10.977  71.932  -10.853 1.00 47.10  ? 699  SER   A C     1 
ATOM   3782  O  O     . SER   C 3 406 ? 10.588  72.917  -11.477 1.00 51.41  ? 699  SER   A O     1 
ATOM   3783  C  CB    . SER   C 3 406 ? 11.259  72.260  -8.377  1.00 55.82  ? 699  SER   A CB    1 
ATOM   3784  O  OG    . SER   C 3 406 ? 10.634  72.212  -7.099  1.00 59.37  ? 699  SER   A OG    1 
ATOM   3785  N  N     . PHE   C 3 407 ? 11.881  71.053  -11.346 1.00 43.71  ? 700  PHE   A N     1 
ATOM   3786  C  CA    . PHE   C 3 407 ? 12.652  71.262  -12.568 1.00 38.16  ? 700  PHE   A CA    1 
ATOM   3787  C  C     . PHE   C 3 407 ? 12.458  70.079  -13.513 1.00 39.45  ? 700  PHE   A C     1 
ATOM   3788  O  O     . PHE   C 3 407 ? 13.395  69.316  -13.755 1.00 38.40  ? 700  PHE   A O     1 
ATOM   3789  C  CB    . PHE   C 3 407 ? 14.126  71.471  -12.204 1.00 34.62  ? 700  PHE   A CB    1 
ATOM   3790  C  CG    . PHE   C 3 407 ? 14.326  72.651  -11.294 1.00 31.30  ? 700  PHE   A CG    1 
ATOM   3791  C  CD1   . PHE   C 3 407 ? 14.091  73.930  -11.747 1.00 32.19  ? 700  PHE   A CD1   1 
ATOM   3792  C  CD2   . PHE   C 3 407 ? 14.649  72.481  -9.961  1.00 35.85  ? 700  PHE   A CD2   1 
ATOM   3793  C  CE1   . PHE   C 3 407 ? 14.224  75.024  -10.901 1.00 34.34  ? 700  PHE   A CE1   1 
ATOM   3794  C  CE2   . PHE   C 3 407 ? 14.780  73.574  -9.112  1.00 36.08  ? 700  PHE   A CE2   1 
ATOM   3795  C  CZ    . PHE   C 3 407 ? 14.564  74.850  -9.585  1.00 34.42  ? 700  PHE   A CZ    1 
ATOM   3796  N  N     . PRO   C 3 408 ? 11.230  69.873  -14.048 1.00 38.53  ? 701  PRO   A N     1 
ATOM   3797  C  CA    . PRO   C 3 408 ? 10.933  68.685  -14.846 1.00 38.37  ? 701  PRO   A CA    1 
ATOM   3798  C  C     . PRO   C 3 408 ? 11.641  68.629  -16.201 1.00 40.87  ? 701  PRO   A C     1 
ATOM   3799  O  O     . PRO   C 3 408 ? 11.848  67.547  -16.752 1.00 42.50  ? 701  PRO   A O     1 
ATOM   3800  C  CB    . PRO   C 3 408 ? 9.400   68.713  -15.005 1.00 39.50  ? 701  PRO   A CB    1 
ATOM   3801  C  CG    . PRO   C 3 408 ? 9.027   70.185  -14.822 1.00 40.54  ? 701  PRO   A CG    1 
ATOM   3802  C  CD    . PRO   C 3 408 ? 10.053  70.741  -13.854 1.00 38.97  ? 701  PRO   A CD    1 
ATOM   3803  N  N     . LYS   C 3 409 ? 12.040  69.773  -16.753 1.00 39.81  ? 702  LYS   A N     1 
ATOM   3804  C  CA    . LYS   C 3 409 ? 12.764  69.707  -18.012 1.00 42.90  ? 702  LYS   A CA    1 
ATOM   3805  C  C     . LYS   C 3 409 ? 14.222  69.337  -17.765 1.00 39.41  ? 702  LYS   A C     1 
ATOM   3806  O  O     . LYS   C 3 409 ? 14.889  68.874  -18.690 1.00 45.69  ? 702  LYS   A O     1 
ATOM   3807  C  CB    . LYS   C 3 409 ? 12.569  70.981  -18.834 1.00 45.43  ? 702  LYS   A CB    1 
ATOM   3808  C  CG    . LYS   C 3 409 ? 11.101  71.282  -19.130 1.00 46.49  ? 702  LYS   A CG    1 
ATOM   3809  C  CD    . LYS   C 3 409 ? 10.796  71.761  -20.525 1.00 46.87  ? 702  LYS   A CD    1 
ATOM   3810  C  CE    . LYS   C 3 409 ? 11.701  72.866  -21.012 1.00 47.45  ? 702  LYS   A CE    1 
ATOM   3811  N  NZ    . LYS   C 3 409 ? 11.044  73.656  -22.082 1.00 49.00  ? 702  LYS   A NZ    1 
ATOM   3812  N  N     . VAL   C 3 410 ? 14.711  69.482  -16.524 1.00 36.39  ? 703  VAL   A N     1 
ATOM   3813  C  CA    . VAL   C 3 410 ? 16.051  69.004  -16.202 1.00 36.01  ? 703  VAL   A CA    1 
ATOM   3814  C  C     . VAL   C 3 410 ? 16.071  67.476  -16.256 1.00 37.98  ? 703  VAL   A C     1 
ATOM   3815  O  O     . VAL   C 3 410 ? 16.975  66.893  -16.869 1.00 36.15  ? 703  VAL   A O     1 
ATOM   3816  C  CB    . VAL   C 3 410 ? 16.561  69.523  -14.847 1.00 33.72  ? 703  VAL   A CB    1 
ATOM   3817  C  CG1   . VAL   C 3 410 ? 17.856  68.828  -14.433 1.00 32.10  ? 703  VAL   A CG1   1 
ATOM   3818  C  CG2   . VAL   C 3 410 ? 16.725  71.038  -14.865 1.00 31.86  ? 703  VAL   A CG2   1 
ATOM   3819  N  N     . ARG   C 3 411 ? 15.058  66.856  -15.632 1.00 37.42  ? 704  ARG   A N     1 
ATOM   3820  C  CA    A ARG   C 3 411 ? 14.925  65.407  -15.634 0.50 38.04  ? 704  ARG   A CA    1 
ATOM   3821  C  CA    B ARG   C 3 411 ? 14.892  65.411  -15.635 0.50 38.39  ? 704  ARG   A CA    1 
ATOM   3822  C  C     . ARG   C 3 411 ? 14.816  64.928  -17.082 1.00 38.75  ? 704  ARG   A C     1 
ATOM   3823  O  O     . ARG   C 3 411 ? 15.488  63.966  -17.458 1.00 38.95  ? 704  ARG   A O     1 
ATOM   3824  C  CB    A ARG   C 3 411 ? 13.722  64.952  -14.796 0.50 39.12  ? 704  ARG   A CB    1 
ATOM   3825  C  CB    B ARG   C 3 411 ? 13.653  65.050  -14.801 0.50 39.96  ? 704  ARG   A CB    1 
ATOM   3826  C  CG    A ARG   C 3 411 ? 13.966  63.742  -13.889 0.50 40.70  ? 704  ARG   A CG    1 
ATOM   3827  C  CG    B ARG   C 3 411 ? 13.179  63.603  -14.894 0.50 41.38  ? 704  ARG   A CG    1 
ATOM   3828  C  CD    A ARG   C 3 411 ? 14.637  62.489  -14.448 0.50 39.08  ? 704  ARG   A CD    1 
ATOM   3829  C  CD    B ARG   C 3 411 ? 12.145  63.290  -13.820 0.50 42.85  ? 704  ARG   A CD    1 
ATOM   3830  N  NE    A ARG   C 3 411 ? 16.055  62.324  -14.106 0.50 38.40  ? 704  ARG   A NE    1 
ATOM   3831  N  NE    B ARG   C 3 411 ? 12.789  62.864  -12.578 0.50 44.25  ? 704  ARG   A NE    1 
ATOM   3832  C  CZ    A ARG   C 3 411 ? 16.527  61.859  -12.956 0.50 37.04  ? 704  ARG   A CZ    1 
ATOM   3833  C  CZ    B ARG   C 3 411 ? 12.163  62.667  -11.427 0.50 40.26  ? 704  ARG   A CZ    1 
ATOM   3834  N  NH1   A ARG   C 3 411 ? 17.828  61.715  -12.785 0.50 35.98  ? 704  ARG   A NH1   1 
ATOM   3835  N  NH1   B ARG   C 3 411 ? 12.851  62.275  -10.370 0.50 42.39  ? 704  ARG   A NH1   1 
ATOM   3836  N  NH2   A ARG   C 3 411 ? 15.702  61.520  -11.983 0.50 42.31  ? 704  ARG   A NH2   1 
ATOM   3837  N  NH2   B ARG   C 3 411 ? 10.863  62.884  -11.336 0.50 38.34  ? 704  ARG   A NH2   1 
ATOM   3838  N  N     . ALA   C 3 412 ? 13.998  65.623  -17.901 1.00 37.79  ? 705  ALA   A N     1 
ATOM   3839  C  CA    . ALA   C 3 412 ? 13.769  65.219  -19.286 1.00 37.84  ? 705  ALA   A CA    1 
ATOM   3840  C  C     . ALA   C 3 412 ? 15.080  65.323  -20.070 1.00 35.50  ? 705  ALA   A C     1 
ATOM   3841  O  O     . ALA   C 3 412 ? 15.358  64.483  -20.921 1.00 35.01  ? 705  ALA   A O     1 
ATOM   3842  C  CB    . ALA   C 3 412 ? 12.667  66.040  -19.936 1.00 36.33  ? 705  ALA   A CB    1 
ATOM   3843  N  N     . TRP   C 3 413 ? 15.877  66.349  -19.742 1.00 34.21  ? 706  TRP   A N     1 
ATOM   3844  C  CA    . TRP   C 3 413 ? 17.168  66.584  -20.367 1.00 34.29  ? 706  TRP   A CA    1 
ATOM   3845  C  C     . TRP   C 3 413 ? 18.157  65.480  -20.017 1.00 32.40  ? 706  TRP   A C     1 
ATOM   3846  O  O     . TRP   C 3 413 ? 18.935  65.056  -20.863 1.00 31.14  ? 706  TRP   A O     1 
ATOM   3847  C  CB    . TRP   C 3 413 ? 17.737  67.959  -19.988 1.00 34.16  ? 706  TRP   A CB    1 
ATOM   3848  C  CG    . TRP   C 3 413 ? 19.090  68.163  -20.593 1.00 32.96  ? 706  TRP   A CG    1 
ATOM   3849  C  CD1   . TRP   C 3 413 ? 19.361  68.526  -21.879 1.00 34.29  ? 706  TRP   A CD1   1 
ATOM   3850  C  CD2   . TRP   C 3 413 ? 20.356  67.903  -19.965 1.00 30.78  ? 706  TRP   A CD2   1 
ATOM   3851  N  NE1   . TRP   C 3 413 ? 20.709  68.533  -22.083 1.00 35.30  ? 706  TRP   A NE1   1 
ATOM   3852  C  CE2   . TRP   C 3 413 ? 21.347  68.153  -20.930 1.00 33.27  ? 706  TRP   A CE2   1 
ATOM   3853  C  CE3   . TRP   C 3 413 ? 20.748  67.468  -18.694 1.00 32.41  ? 706  TRP   A CE3   1 
ATOM   3854  C  CZ2   . TRP   C 3 413 ? 22.710  68.008  -20.655 1.00 32.68  ? 706  TRP   A CZ2   1 
ATOM   3855  C  CZ3   . TRP   C 3 413 ? 22.090  67.325  -18.421 1.00 32.42  ? 706  TRP   A CZ3   1 
ATOM   3856  C  CH2   . TRP   C 3 413 ? 23.059  67.596  -19.392 1.00 32.00  ? 706  TRP   A CH2   1 
ATOM   3857  N  N     . ILE   C 3 414 ? 18.175  65.067  -18.753 1.00 33.08  ? 707  ILE   A N     1 
ATOM   3858  C  CA    . ILE   C 3 414 ? 19.060  63.992  -18.341 1.00 35.21  ? 707  ILE   A CA    1 
ATOM   3859  C  C     . ILE   C 3 414 ? 18.724  62.732  -19.139 1.00 41.39  ? 707  ILE   A C     1 
ATOM   3860  O  O     . ILE   C 3 414 ? 19.624  62.040  -19.636 1.00 35.13  ? 707  ILE   A O     1 
ATOM   3861  C  CB    . ILE   C 3 414 ? 18.958  63.754  -16.820 1.00 35.08  ? 707  ILE   A CB    1 
ATOM   3862  C  CG1   . ILE   C 3 414 ? 19.533  64.921  -16.017 1.00 31.95  ? 707  ILE   A CG1   1 
ATOM   3863  C  CG2   . ILE   C 3 414 ? 19.608  62.435  -16.423 1.00 37.52  ? 707  ILE   A CG2   1 
ATOM   3864  C  CD1   . ILE   C 3 414 ? 19.181  64.878  -14.546 1.00 34.78  ? 707  ILE   A CD1   1 
ATOM   3865  N  N     . GLU   C 3 415 ? 17.415  62.444  -19.257 1.00 43.72  ? 708  GLU   A N     1 
ATOM   3866  C  CA    . GLU   C 3 415 ? 16.955  61.227  -19.914 1.00 41.79  ? 708  GLU   A CA    1 
ATOM   3867  C  C     . GLU   C 3 415 ? 17.297  61.263  -21.403 1.00 40.53  ? 708  GLU   A C     1 
ATOM   3868  O  O     . GLU   C 3 415 ? 17.730  60.260  -21.968 1.00 40.10  ? 708  GLU   A O     1 
ATOM   3869  C  CB    . GLU   C 3 415 ? 15.462  60.992  -19.654 1.00 48.14  ? 708  GLU   A CB    1 
ATOM   3870  C  CG    . GLU   C 3 415 ? 15.185  60.341  -18.295 1.00 54.90  ? 708  GLU   A CG    1 
ATOM   3871  C  CD    . GLU   C 3 415 ? 16.119  59.184  -17.929 1.00 63.01  ? 708  GLU   A CD    1 
ATOM   3872  O  OE1   . GLU   C 3 415 ? 16.241  58.227  -18.762 1.00 65.31  ? 708  GLU   A OE1   1 
ATOM   3873  O  OE2   . GLU   C 3 415 ? 16.759  59.249  -16.829 1.00 55.92  ? 708  GLU   A OE2   1 
ATOM   3874  N  N     . LYS   C 3 416 ? 17.126  62.420  -22.046 1.00 38.61  ? 709  LYS   A N     1 
ATOM   3875  C  CA    . LYS   C 3 416 ? 17.460  62.526  -23.458 1.00 39.18  ? 709  LYS   A CA    1 
ATOM   3876  C  C     . LYS   C 3 416 ? 18.961  62.316  -23.670 1.00 37.35  ? 709  LYS   A C     1 
ATOM   3877  O  O     . LYS   C 3 416 ? 19.375  61.612  -24.582 1.00 37.10  ? 709  LYS   A O     1 
ATOM   3878  C  CB    . LYS   C 3 416 ? 17.031  63.889  -23.989 1.00 44.31  ? 709  LYS   A CB    1 
ATOM   3879  C  CG    . LYS   C 3 416 ? 16.959  63.960  -25.503 1.00 52.11  ? 709  LYS   A CG    1 
ATOM   3880  C  CD    . LYS   C 3 416 ? 16.618  65.338  -25.986 1.00 59.95  ? 709  LYS   A CD    1 
ATOM   3881  C  CE    . LYS   C 3 416 ? 16.617  65.440  -27.498 1.00 66.37  ? 709  LYS   A CE    1 
ATOM   3882  N  NZ    . LYS   C 3 416 ? 16.444  66.848  -27.918 1.00 69.33  ? 709  LYS   A NZ    1 
ATOM   3883  N  N     . THR   C 3 417 ? 19.767  62.941  -22.803 1.00 34.22  ? 710  THR   A N     1 
ATOM   3884  C  CA    . THR   C 3 417 ? 21.216  62.858  -22.842 1.00 33.10  ? 710  THR   A CA    1 
ATOM   3885  C  C     . THR   C 3 417 ? 21.687  61.412  -22.727 1.00 32.88  ? 710  THR   A C     1 
ATOM   3886  O  O     . THR   C 3 417 ? 22.531  60.961  -23.508 1.00 38.31  ? 710  THR   A O     1 
ATOM   3887  C  CB    . THR   C 3 417 ? 21.786  63.795  -21.772 1.00 31.14  ? 710  THR   A CB    1 
ATOM   3888  O  OG1   . THR   C 3 417 ? 21.347  65.100  -22.150 1.00 28.30  ? 710  THR   A OG1   1 
ATOM   3889  C  CG2   . THR   C 3 417 ? 23.290  63.748  -21.657 1.00 29.36  ? 710  THR   A CG2   1 
ATOM   3890  N  N     . LEU   C 3 418 ? 21.128  60.689  -21.764 1.00 33.67  ? 711  LEU   A N     1 
ATOM   3891  C  CA    . LEU   C 3 418 ? 21.486  59.297  -21.541 1.00 35.56  ? 711  LEU   A CA    1 
ATOM   3892  C  C     . LEU   C 3 418 ? 21.026  58.404  -22.699 1.00 37.71  ? 711  LEU   A C     1 
ATOM   3893  O  O     . LEU   C 3 418 ? 21.754  57.518  -23.116 1.00 36.16  ? 711  LEU   A O     1 
ATOM   3894  C  CB    . LEU   C 3 418 ? 20.849  58.856  -20.220 1.00 34.89  ? 711  LEU   A CB    1 
ATOM   3895  C  CG    . LEU   C 3 418 ? 21.457  59.489  -18.969 1.00 35.27  ? 711  LEU   A CG    1 
ATOM   3896  C  CD1   . LEU   C 3 418 ? 20.802  58.950  -17.702 1.00 34.80  ? 711  LEU   A CD1   1 
ATOM   3897  C  CD2   . LEU   C 3 418 ? 22.960  59.284  -18.912 1.00 33.45  ? 711  LEU   A CD2   1 
ATOM   3898  N  N     . GLU   C 3 419 ? 19.819  58.638  -23.224 1.00 42.93  ? 712  GLU   A N     1 
ATOM   3899  C  CA    . GLU   C 3 419 ? 19.253  57.812  -24.284 1.00 47.58  ? 712  GLU   A CA    1 
ATOM   3900  C  C     . GLU   C 3 419 ? 20.133  57.906  -25.535 1.00 44.31  ? 712  GLU   A C     1 
ATOM   3901  O  O     . GLU   C 3 419 ? 20.492  56.886  -26.109 1.00 47.05  ? 712  GLU   A O     1 
ATOM   3902  C  CB    . GLU   C 3 419 ? 17.781  58.199  -24.495 1.00 52.59  ? 712  GLU   A CB    1 
ATOM   3903  C  CG    . GLU   C 3 419 ? 17.014  57.345  -25.496 1.00 60.78  ? 712  GLU   A CG    1 
ATOM   3904  C  CD    . GLU   C 3 419 ? 17.171  57.735  -26.961 1.00 74.71  ? 712  GLU   A CD    1 
ATOM   3905  O  OE1   . GLU   C 3 419 ? 17.258  58.963  -27.239 1.00 83.44  ? 712  GLU   A OE1   1 
ATOM   3906  O  OE2   . GLU   C 3 419 ? 17.174  56.817  -27.837 1.00 75.17  ? 712  GLU   A OE2   1 
ATOM   3907  N  N     . GLU   C 3 420 ? 20.508  59.129  -25.921 1.00 46.20  ? 713  GLU   A N     1 
ATOM   3908  C  CA    . GLU   C 3 420 ? 21.419  59.392  -27.027 1.00 44.68  ? 713  GLU   A CA    1 
ATOM   3909  C  C     . GLU   C 3 420 ? 22.817  58.842  -26.738 1.00 40.88  ? 713  GLU   A C     1 
ATOM   3910  O  O     . GLU   C 3 420 ? 23.456  58.290  -27.626 1.00 35.30  ? 713  GLU   A O     1 
ATOM   3911  C  CB    . GLU   C 3 420 ? 21.511  60.902  -27.253 1.00 52.52  ? 713  GLU   A CB    1 
ATOM   3912  C  CG    . GLU   C 3 420 ? 21.613  61.325  -28.712 1.00 65.78  ? 713  GLU   A CG    1 
ATOM   3913  C  CD    . GLU   C 3 420 ? 21.614  62.833  -28.956 1.00 76.52  ? 713  GLU   A CD    1 
ATOM   3914  O  OE1   . GLU   C 3 420 ? 21.470  63.629  -27.967 1.00 77.22  ? 713  GLU   A OE1   1 
ATOM   3915  O  OE2   . GLU   C 3 420 ? 21.762  63.219  -30.142 1.00 77.92  ? 713  GLU   A OE2   1 
ATOM   3916  N  N     . GLY   C 3 421 ? 23.322  59.039  -25.510 1.00 37.89  ? 714  GLY   A N     1 
ATOM   3917  C  CA    . GLY   C 3 421 ? 24.623  58.503  -25.125 1.00 37.66  ? 714  GLY   A CA    1 
ATOM   3918  C  C     . GLY   C 3 421 ? 24.676  56.976  -25.210 1.00 38.31  ? 714  GLY   A C     1 
ATOM   3919  O  O     . GLY   C 3 421 ? 25.708  56.379  -25.535 1.00 36.83  ? 714  GLY   A O     1 
ATOM   3920  N  N     . ARG   C 3 422 ? 23.532  56.352  -24.925 1.00 37.81  ? 715  ARG   A N     1 
ATOM   3921  C  CA    . ARG   C 3 422 ? 23.373  54.914  -25.057 1.00 39.30  ? 715  ARG   A CA    1 
ATOM   3922  C  C     . ARG   C 3 422 ? 23.518  54.474  -26.519 1.00 40.50  ? 715  ARG   A C     1 
ATOM   3923  O  O     . ARG   C 3 422 ? 24.174  53.473  -26.797 1.00 39.51  ? 715  ARG   A O     1 
ATOM   3924  C  CB    . ARG   C 3 422 ? 22.010  54.546  -24.473 1.00 42.24  ? 715  ARG   A CB    1 
ATOM   3925  C  CG    . ARG   C 3 422 ? 22.062  53.463  -23.411 1.00 46.75  ? 715  ARG   A CG    1 
ATOM   3926  C  CD    . ARG   C 3 422 ? 21.305  53.785  -22.140 1.00 47.38  ? 715  ARG   A CD    1 
ATOM   3927  N  NE    . ARG   C 3 422 ? 19.952  54.248  -22.372 1.00 45.31  ? 715  ARG   A NE    1 
ATOM   3928  C  CZ    . ARG   C 3 422 ? 19.268  54.999  -21.513 1.00 43.31  ? 715  ARG   A CZ    1 
ATOM   3929  N  NH1   . ARG   C 3 422 ? 19.667  55.138  -20.260 1.00 39.33  ? 715  ARG   A NH1   1 
ATOM   3930  N  NH2   . ARG   C 3 422 ? 18.180  55.616  -21.925 1.00 46.01  ? 715  ARG   A NH2   1 
ATOM   3931  N  N     . ARG   C 3 423 ? 22.927  55.227  -27.462 1.00 39.53  ? 716  ARG   A N     1 
ATOM   3932  C  CA    . ARG   C 3 423 ? 22.937  54.852  -28.875 1.00 43.33  ? 716  ARG   A CA    1 
ATOM   3933  C  C     . ARG   C 3 423 ? 24.266  55.208  -29.555 1.00 41.05  ? 716  ARG   A C     1 
ATOM   3934  O  O     . ARG   C 3 423 ? 24.742  54.451  -30.388 1.00 43.01  ? 716  ARG   A O     1 
ATOM   3935  C  CB    . ARG   C 3 423 ? 21.766  55.496  -29.625 1.00 48.30  ? 716  ARG   A CB    1 
ATOM   3936  C  CG    . ARG   C 3 423 ? 20.427  54.793  -29.434 1.00 54.82  ? 716  ARG   A CG    1 
ATOM   3937  C  CD    . ARG   C 3 423 ? 19.388  55.290  -30.439 1.00 62.66  ? 716  ARG   A CD    1 
ATOM   3938  N  NE    . ARG   C 3 423 ? 19.134  56.720  -30.302 1.00 66.78  ? 716  ARG   A NE    1 
ATOM   3939  C  CZ    . ARG   C 3 423 ? 19.666  57.678  -31.065 1.00 74.32  ? 716  ARG   A CZ    1 
ATOM   3940  N  NH1   . ARG   C 3 423 ? 20.029  57.424  -32.311 1.00 71.56  ? 716  ARG   A NH1   1 
ATOM   3941  N  NH2   . ARG   C 3 423 ? 19.821  58.901  -30.576 1.00 76.43  ? 716  ARG   A NH2   1 
ATOM   3942  N  N     . ARG   C 3 424 ? 24.875  56.352  -29.208 1.00 39.20  ? 717  ARG   A N     1 
ATOM   3943  C  CA    . ARG   C 3 424 ? 26.090  56.816  -29.865 1.00 36.89  ? 717  ARG   A CA    1 
ATOM   3944  C  C     . ARG   C 3 424 ? 27.369  56.328  -29.179 1.00 33.00  ? 717  ARG   A C     1 
ATOM   3945  O  O     . ARG   C 3 424 ? 28.408  56.184  -29.825 1.00 36.86  ? 717  ARG   A O     1 
ATOM   3946  C  CB    . ARG   C 3 424 ? 26.106  58.338  -29.900 1.00 36.21  ? 717  ARG   A CB    1 
ATOM   3947  C  CG    . ARG   C 3 424 ? 25.109  58.986  -30.854 1.00 41.87  ? 717  ARG   A CG    1 
ATOM   3948  C  CD    . ARG   C 3 424 ? 25.100  60.441  -30.434 1.00 47.42  ? 717  ARG   A CD    1 
ATOM   3949  N  NE    . ARG   C 3 424 ? 24.538  61.458  -31.306 1.00 60.15  ? 717  ARG   A NE    1 
ATOM   3950  C  CZ    . ARG   C 3 424 ? 24.646  62.771  -31.060 1.00 68.59  ? 717  ARG   A CZ    1 
ATOM   3951  N  NH1   . ARG   C 3 424 ? 24.370  63.646  -32.013 1.00 75.33  ? 717  ARG   A NH1   1 
ATOM   3952  N  NH2   . ARG   C 3 424 ? 25.058  63.211  -29.872 1.00 63.34  ? 717  ARG   A NH2   1 
ATOM   3953  N  N     . GLY   C 3 425 ? 27.306  56.129  -27.859 1.00 33.58  ? 718  GLY   A N     1 
ATOM   3954  C  CA    . GLY   C 3 425 ? 28.450  55.744  -27.048 1.00 32.83  ? 718  GLY   A CA    1 
ATOM   3955  C  C     . GLY   C 3 425 ? 29.260  56.953  -26.581 1.00 33.54  ? 718  GLY   A C     1 
ATOM   3956  O  O     . GLY   C 3 425 ? 30.337  56.810  -25.994 1.00 31.60  ? 718  GLY   A O     1 
ATOM   3957  N  N     . TYR   C 3 426 ? 28.726  58.149  -26.857 1.00 36.00  ? 719  TYR   A N     1 
ATOM   3958  C  CA    . TYR   C 3 426 ? 29.353  59.385  -26.422 1.00 35.10  ? 719  TYR   A CA    1 
ATOM   3959  C  C     . TYR   C 3 426 ? 28.284  60.418  -26.111 1.00 31.12  ? 719  TYR   A C     1 
ATOM   3960  O  O     . TYR   C 3 426 ? 27.131  60.242  -26.484 1.00 27.10  ? 719  TYR   A O     1 
ATOM   3961  C  CB    . TYR   C 3 426 ? 30.351  59.904  -27.456 1.00 35.42  ? 719  TYR   A CB    1 
ATOM   3962  C  CG    . TYR   C 3 426 ? 29.788  60.324  -28.787 1.00 37.34  ? 719  TYR   A CG    1 
ATOM   3963  C  CD1   . TYR   C 3 426 ? 29.214  61.578  -28.955 1.00 37.92  ? 719  TYR   A CD1   1 
ATOM   3964  C  CD2   . TYR   C 3 426 ? 29.903  59.504  -29.905 1.00 37.17  ? 719  TYR   A CD2   1 
ATOM   3965  C  CE1   . TYR   C 3 426 ? 28.746  61.999  -30.186 1.00 36.69  ? 719  TYR   A CE1   1 
ATOM   3966  C  CE2   . TYR   C 3 426 ? 29.401  59.896  -31.142 1.00 35.57  ? 719  TYR   A CE2   1 
ATOM   3967  C  CZ    . TYR   C 3 426 ? 28.808  61.142  -31.276 1.00 39.26  ? 719  TYR   A CZ    1 
ATOM   3968  O  OH    . TYR   C 3 426 ? 28.326  61.569  -32.492 1.00 42.90  ? 719  TYR   A OH    1 
ATOM   3969  N  N     . VAL   C 3 427 ? 28.695  61.437  -25.342 1.00 30.86  ? 720  VAL   A N     1 
ATOM   3970  C  CA    . VAL   C 3 427 ? 27.887  62.606  -25.033 1.00 30.15  ? 720  VAL   A CA    1 
ATOM   3971  C  C     . VAL   C 3 427 ? 28.694  63.808  -25.498 1.00 29.78  ? 720  VAL   A C     1 
ATOM   3972  O  O     . VAL   C 3 427 ? 29.878  63.649  -25.804 1.00 27.47  ? 720  VAL   A O     1 
ATOM   3973  C  CB    . VAL   C 3 427 ? 27.549  62.677  -23.532 1.00 29.63  ? 720  VAL   A CB    1 
ATOM   3974  C  CG1   . VAL   C 3 427 ? 26.600  61.561  -23.104 1.00 31.06  ? 720  VAL   A CG1   1 
ATOM   3975  C  CG2   . VAL   C 3 427 ? 28.794  62.630  -22.679 1.00 31.97  ? 720  VAL   A CG2   1 
ATOM   3976  N  N     . GLU   C 3 428 ? 28.075  64.995  -25.572 1.00 30.24  ? 721  GLU   A N     1 
ATOM   3977  C  CA    . GLU   C 3 428 ? 28.802  66.113  -26.145 1.00 34.10  ? 721  GLU   A CA    1 
ATOM   3978  C  C     . GLU   C 3 428 ? 28.283  67.435  -25.599 1.00 31.85  ? 721  GLU   A C     1 
ATOM   3979  O  O     . GLU   C 3 428 ? 27.208  67.508  -25.013 1.00 31.58  ? 721  GLU   A O     1 
ATOM   3980  C  CB    . GLU   C 3 428 ? 28.767  66.062  -27.675 1.00 37.09  ? 721  GLU   A CB    1 
ATOM   3981  C  CG    . GLU   C 3 428 ? 27.363  66.075  -28.229 1.00 47.13  ? 721  GLU   A CG    1 
ATOM   3982  C  CD    . GLU   C 3 428 ? 27.226  66.051  -29.740 1.00 48.49  ? 721  GLU   A CD    1 
ATOM   3983  O  OE1   . GLU   C 3 428 ? 28.168  65.613  -30.447 1.00 48.90  ? 721  GLU   A OE1   1 
ATOM   3984  O  OE2   . GLU   C 3 428 ? 26.148  66.454  -30.180 1.00 53.01  ? 721  GLU   A OE2   1 
ATOM   3985  N  N     . THR   C 3 429 ? 29.134  68.450  -25.731 1.00 28.74  ? 722  THR   A N     1 
ATOM   3986  C  CA    . THR   C 3 429 ? 28.844  69.791  -25.268 1.00 28.58  ? 722  THR   A CA    1 
ATOM   3987  C  C     . THR   C 3 429 ? 28.071  70.536  -26.357 1.00 30.15  ? 722  THR   A C     1 
ATOM   3988  O  O     . THR   C 3 429 ? 27.851  70.034  -27.461 1.00 30.89  ? 722  THR   A O     1 
ATOM   3989  C  CB    . THR   C 3 429 ? 30.150  70.523  -24.922 1.00 25.76  ? 722  THR   A CB    1 
ATOM   3990  O  OG1   . THR   C 3 429 ? 30.851  70.821  -26.131 1.00 25.54  ? 722  THR   A OG1   1 
ATOM   3991  C  CG2   . THR   C 3 429 ? 31.034  69.701  -24.019 1.00 26.11  ? 722  THR   A CG2   1 
ATOM   3992  N  N     . LEU   C 3 430 ? 27.705  71.766  -26.030 1.00 29.55  ? 723  LEU   A N     1 
ATOM   3993  C  CA    . LEU   C 3 430 ? 26.960  72.645  -26.913 1.00 31.41  ? 723  LEU   A CA    1 
ATOM   3994  C  C     . LEU   C 3 430 ? 27.723  72.893  -28.217 1.00 31.97  ? 723  LEU   A C     1 
ATOM   3995  O  O     . LEU   C 3 430 ? 27.107  73.130  -29.255 1.00 37.99  ? 723  LEU   A O     1 
ATOM   3996  C  CB    . LEU   C 3 430 ? 26.750  73.939  -26.122 1.00 31.36  ? 723  LEU   A CB    1 
ATOM   3997  C  CG    . LEU   C 3 430 ? 25.964  75.052  -26.810 1.00 32.45  ? 723  LEU   A CG    1 
ATOM   3998  C  CD1   . LEU   C 3 430 ? 24.487  74.703  -26.851 1.00 32.67  ? 723  LEU   A CD1   1 
ATOM   3999  C  CD2   . LEU   C 3 430 ? 26.200  76.364  -26.072 1.00 31.91  ? 723  LEU   A CD2   1 
ATOM   4000  N  N     . PHE   C 3 431 ? 29.061  72.880  -28.151 1.00 31.85  ? 724  PHE   A N     1 
ATOM   4001  C  CA    . PHE   C 3 431 ? 29.895  73.116  -29.311 1.00 30.22  ? 724  PHE   A CA    1 
ATOM   4002  C  C     . PHE   C 3 431 ? 30.362  71.802  -29.932 1.00 29.56  ? 724  PHE   A C     1 
ATOM   4003  O  O     . PHE   C 3 431 ? 31.117  71.797  -30.891 1.00 33.96  ? 724  PHE   A O     1 
ATOM   4004  C  CB    . PHE   C 3 431 ? 31.110  73.955  -28.927 1.00 35.58  ? 724  PHE   A CB    1 
ATOM   4005  C  CG    . PHE   C 3 431 ? 30.785  75.266  -28.262 1.00 39.77  ? 724  PHE   A CG    1 
ATOM   4006  C  CD1   . PHE   C 3 431 ? 30.480  75.322  -26.913 1.00 43.56  ? 724  PHE   A CD1   1 
ATOM   4007  C  CD2   . PHE   C 3 431 ? 30.775  76.434  -28.989 1.00 40.97  ? 724  PHE   A CD2   1 
ATOM   4008  C  CE1   . PHE   C 3 431 ? 30.170  76.536  -26.321 1.00 46.82  ? 724  PHE   A CE1   1 
ATOM   4009  C  CE2   . PHE   C 3 431 ? 30.478  77.645  -28.390 1.00 42.30  ? 724  PHE   A CE2   1 
ATOM   4010  C  CZ    . PHE   C 3 431 ? 30.179  77.696  -27.061 1.00 42.07  ? 724  PHE   A CZ    1 
ATOM   4011  N  N     . GLY   C 3 432 ? 29.949  70.672  -29.377 1.00 31.05  ? 725  GLY   A N     1 
ATOM   4012  C  CA    . GLY   C 3 432 ? 30.194  69.403  -30.032 1.00 31.04  ? 725  GLY   A CA    1 
ATOM   4013  C  C     . GLY   C 3 432 ? 31.444  68.716  -29.505 1.00 33.03  ? 725  GLY   A C     1 
ATOM   4014  O  O     . GLY   C 3 432 ? 31.823  67.680  -30.036 1.00 40.20  ? 725  GLY   A O     1 
ATOM   4015  N  N     . ARG   C 3 433 ? 32.067  69.257  -28.446 1.00 35.63  ? 726  ARG   A N     1 
ATOM   4016  C  CA    . ARG   C 3 433 ? 33.118  68.515  -27.764 1.00 34.19  ? 726  ARG   A CA    1 
ATOM   4017  C  C     . ARG   C 3 433 ? 32.520  67.218  -27.215 1.00 33.20  ? 726  ARG   A C     1 
ATOM   4018  O  O     . ARG   C 3 433 ? 31.396  67.198  -26.725 1.00 30.65  ? 726  ARG   A O     1 
ATOM   4019  C  CB    . ARG   C 3 433 ? 33.762  69.322  -26.640 1.00 33.26  ? 726  ARG   A CB    1 
ATOM   4020  C  CG    . ARG   C 3 433 ? 35.047  68.702  -26.102 1.00 32.17  ? 726  ARG   A CG    1 
ATOM   4021  C  CD    . ARG   C 3 433 ? 35.494  69.319  -24.786 1.00 31.07  ? 726  ARG   A CD    1 
ATOM   4022  N  NE    . ARG   C 3 433 ? 35.816  70.730  -24.932 1.00 30.99  ? 726  ARG   A NE    1 
ATOM   4023  C  CZ    . ARG   C 3 433 ? 36.969  71.190  -25.412 1.00 33.58  ? 726  ARG   A CZ    1 
ATOM   4024  N  NH1   . ARG   C 3 433 ? 37.976  70.354  -25.653 1.00 28.79  ? 726  ARG   A NH1   1 
ATOM   4025  N  NH2   . ARG   C 3 433 ? 37.088  72.487  -25.665 1.00 32.71  ? 726  ARG   A NH2   1 
ATOM   4026  N  N     . ARG   C 3 434 ? 33.296  66.138  -27.268 1.00 32.53  ? 727  ARG   A N     1 
ATOM   4027  C  CA    . ARG   C 3 434 ? 32.741  64.802  -27.116 1.00 34.98  ? 727  ARG   A CA    1 
ATOM   4028  C  C     . ARG   C 3 434 ? 33.497  64.020  -26.042 1.00 32.16  ? 727  ARG   A C     1 
ATOM   4029  O  O     . ARG   C 3 434 ? 34.717  64.152  -25.914 1.00 31.64  ? 727  ARG   A O     1 
ATOM   4030  C  CB    . ARG   C 3 434 ? 32.819  64.210  -28.519 1.00 40.80  ? 727  ARG   A CB    1 
ATOM   4031  C  CG    . ARG   C 3 434 ? 32.774  62.703  -28.632 1.00 47.92  ? 727  ARG   A CG    1 
ATOM   4032  C  CD    . ARG   C 3 434 ? 33.161  62.377  -30.060 1.00 52.54  ? 727  ARG   A CD    1 
ATOM   4033  N  NE    . ARG   C 3 434 ? 32.205  62.948  -30.995 1.00 56.17  ? 727  ARG   A NE    1 
ATOM   4034  C  CZ    . ARG   C 3 434 ? 32.348  62.934  -32.312 1.00 55.51  ? 727  ARG   A CZ    1 
ATOM   4035  N  NH1   . ARG   C 3 434 ? 33.309  62.198  -32.851 1.00 54.50  ? 727  ARG   A NH1   1 
ATOM   4036  N  NH2   . ARG   C 3 434 ? 31.539  63.669  -33.065 1.00 49.14  ? 727  ARG   A NH2   1 
ATOM   4037  N  N     . ARG   C 3 435 ? 32.757  63.238  -25.245 1.00 29.39  ? 728  ARG   A N     1 
ATOM   4038  C  CA    . ARG   C 3 435 ? 33.357  62.296  -24.315 1.00 30.12  ? 728  ARG   A CA    1 
ATOM   4039  C  C     . ARG   C 3 435 ? 32.705  60.932  -24.521 1.00 31.13  ? 728  ARG   A C     1 
ATOM   4040  O  O     . ARG   C 3 435 ? 31.495  60.817  -24.393 1.00 32.89  ? 728  ARG   A O     1 
ATOM   4041  C  CB    . ARG   C 3 435 ? 33.178  62.759  -22.862 1.00 31.38  ? 728  ARG   A CB    1 
ATOM   4042  C  CG    . ARG   C 3 435 ? 33.801  61.824  -21.842 1.00 30.74  ? 728  ARG   A CG    1 
ATOM   4043  C  CD    . ARG   C 3 435 ? 33.307  62.031  -20.434 1.00 33.66  ? 728  ARG   A CD    1 
ATOM   4044  N  NE    . ARG   C 3 435 ? 34.049  61.206  -19.474 1.00 31.95  ? 728  ARG   A NE    1 
ATOM   4045  C  CZ    . ARG   C 3 435 ? 34.006  61.378  -18.146 1.00 34.15  ? 728  ARG   A CZ    1 
ATOM   4046  N  NH1   . ARG   C 3 435 ? 33.486  62.481  -17.631 1.00 33.05  ? 728  ARG   A NH1   1 
ATOM   4047  N  NH2   . ARG   C 3 435 ? 34.515  60.463  -17.333 1.00 31.47  ? 728  ARG   A NH2   1 
ATOM   4048  N  N     . TYR   C 3 436 ? 33.526  59.912  -24.815 1.00 33.54  ? 729  TYR   A N     1 
ATOM   4049  C  CA    . TYR   C 3 436 ? 33.100  58.516  -24.897 1.00 35.46  ? 729  TYR   A CA    1 
ATOM   4050  C  C     . TYR   C 3 436 ? 32.872  57.973  -23.500 1.00 35.17  ? 729  TYR   A C     1 
ATOM   4051  O  O     . TYR   C 3 436 ? 33.773  58.060  -22.657 1.00 37.90  ? 729  TYR   A O     1 
ATOM   4052  C  CB    . TYR   C 3 436 ? 34.152  57.664  -25.617 1.00 32.22  ? 729  TYR   A CB    1 
ATOM   4053  C  CG    . TYR   C 3 436 ? 34.214  58.016  -27.078 1.00 32.86  ? 729  TYR   A CG    1 
ATOM   4054  C  CD1   . TYR   C 3 436 ? 33.355  57.424  -27.982 1.00 31.06  ? 729  TYR   A CD1   1 
ATOM   4055  C  CD2   . TYR   C 3 436 ? 35.018  59.045  -27.532 1.00 34.98  ? 729  TYR   A CD2   1 
ATOM   4056  C  CE1   . TYR   C 3 436 ? 33.338  57.801  -29.313 1.00 32.69  ? 729  TYR   A CE1   1 
ATOM   4057  C  CE2   . TYR   C 3 436 ? 35.021  59.424  -28.864 1.00 35.61  ? 729  TYR   A CE2   1 
ATOM   4058  C  CZ    . TYR   C 3 436 ? 34.176  58.799  -29.760 1.00 32.33  ? 729  TYR   A CZ    1 
ATOM   4059  O  OH    . TYR   C 3 436 ? 34.149  59.154  -31.088 1.00 32.61  ? 729  TYR   A OH    1 
ATOM   4060  N  N     . VAL   C 3 437 ? 31.666  57.454  -23.273 1.00 35.31  ? 730  VAL   A N     1 
ATOM   4061  C  CA    . VAL   C 3 437 ? 31.306  56.907  -21.976 1.00 38.84  ? 730  VAL   A CA    1 
ATOM   4062  C  C     . VAL   C 3 437 ? 30.821  55.476  -22.166 1.00 40.64  ? 730  VAL   A C     1 
ATOM   4063  O  O     . VAL   C 3 437 ? 29.677  55.234  -22.543 1.00 41.34  ? 730  VAL   A O     1 
ATOM   4064  C  CB    . VAL   C 3 437 ? 30.254  57.731  -21.208 1.00 36.74  ? 730  VAL   A CB    1 
ATOM   4065  C  CG1   . VAL   C 3 437 ? 30.183  57.267  -19.750 1.00 36.44  ? 730  VAL   A CG1   1 
ATOM   4066  C  CG2   . VAL   C 3 437 ? 30.506  59.227  -21.278 1.00 36.70  ? 730  VAL   A CG2   1 
ATOM   4067  N  N     . PRO   C 3 438 ? 31.687  54.487  -21.871 1.00 47.74  ? 731  PRO   A N     1 
ATOM   4068  C  CA    . PRO   C 3 438 ? 31.281  53.086  -21.888 1.00 48.05  ? 731  PRO   A CA    1 
ATOM   4069  C  C     . PRO   C 3 438 ? 30.439  52.789  -20.659 1.00 44.75  ? 731  PRO   A C     1 
ATOM   4070  O  O     . PRO   C 3 438 ? 30.423  53.562  -19.702 1.00 49.04  ? 731  PRO   A O     1 
ATOM   4071  C  CB    . PRO   C 3 438 ? 32.618  52.326  -21.873 1.00 49.74  ? 731  PRO   A CB    1 
ATOM   4072  C  CG    . PRO   C 3 438 ? 33.579  53.257  -21.162 1.00 49.60  ? 731  PRO   A CG    1 
ATOM   4073  C  CD    . PRO   C 3 438 ? 33.093  54.662  -21.471 1.00 52.06  ? 731  PRO   A CD    1 
ATOM   4074  N  N     . ASP   C 3 439 ? 29.798  51.621  -20.663 1.00 46.61  ? 732  ASP   A N     1 
ATOM   4075  C  CA    . ASP   C 3 439 ? 29.068  51.112  -19.470 1.00 45.16  ? 732  ASP   A CA    1 
ATOM   4076  C  C     . ASP   C 3 439 ? 27.716  51.795  -19.276 1.00 43.82  ? 732  ASP   A C     1 
ATOM   4077  O  O     . ASP   C 3 439 ? 27.133  51.622  -18.204 1.00 44.45  ? 732  ASP   A O     1 
ATOM   4078  C  CB    . ASP   C 3 439 ? 29.953  51.149  -18.224 1.00 48.39  ? 732  ASP   A CB    1 
ATOM   4079  C  CG    . ASP   C 3 439 ? 31.187  50.274  -18.324 1.00 51.82  ? 732  ASP   A CG    1 
ATOM   4080  O  OD1   . ASP   C 3 439 ? 31.083  49.181  -18.904 1.00 52.14  ? 732  ASP   A OD1   1 
ATOM   4081  O  OD2   . ASP   C 3 439 ? 32.238  50.694  -17.813 1.00 55.44  ? 732  ASP   A OD2   1 
ATOM   4082  N  N     . LEU   C 3 440 ? 27.221  52.496  -20.286 1.00 43.65  ? 733  LEU   A N     1 
ATOM   4083  C  CA    . LEU   C 3 440 ? 25.887  53.068  -20.142 1.00 46.70  ? 733  LEU   A CA    1 
ATOM   4084  C  C     . LEU   C 3 440 ? 24.804  51.982  -20.144 1.00 53.54  ? 733  LEU   A C     1 
ATOM   4085  O  O     . LEU   C 3 440 ? 23.689  52.230  -19.667 1.00 51.93  ? 733  LEU   A O     1 
ATOM   4086  C  CB    . LEU   C 3 440 ? 25.656  54.089  -21.255 1.00 41.41  ? 733  LEU   A CB    1 
ATOM   4087  C  CG    . LEU   C 3 440 ? 26.344  55.437  -21.045 1.00 41.38  ? 733  LEU   A CG    1 
ATOM   4088  C  CD1   . LEU   C 3 440 ? 26.087  56.363  -22.222 1.00 39.96  ? 733  LEU   A CD1   1 
ATOM   4089  C  CD2   . LEU   C 3 440 ? 25.872  56.084  -19.753 1.00 44.36  ? 733  LEU   A CD2   1 
ATOM   4090  N  N     . GLU   C 3 441 ? 25.133  50.796  -20.685 1.00 56.95  ? 734  GLU   A N     1 
ATOM   4091  C  CA    . GLU   C 3 441 ? 24.209  49.669  -20.722 1.00 62.81  ? 734  GLU   A CA    1 
ATOM   4092  C  C     . GLU   C 3 441 ? 24.748  48.480  -19.921 1.00 62.51  ? 734  GLU   A C     1 
ATOM   4093  O  O     . GLU   C 3 441 ? 24.284  47.364  -20.121 1.00 66.53  ? 734  GLU   A O     1 
ATOM   4094  C  CB    . GLU   C 3 441 ? 23.900  49.306  -22.181 1.00 64.17  ? 734  GLU   A CB    1 
ATOM   4095  C  CG    . GLU   C 3 441 ? 22.597  49.926  -22.678 1.00 64.85  ? 734  GLU   A CG    1 
ATOM   4096  C  CD    . GLU   C 3 441 ? 22.432  50.053  -24.184 1.00 65.87  ? 734  GLU   A CD    1 
ATOM   4097  O  OE1   . GLU   C 3 441 ? 23.433  49.928  -24.913 1.00 71.18  ? 734  GLU   A OE1   1 
ATOM   4098  O  OE2   . GLU   C 3 441 ? 21.291  50.263  -24.630 1.00 70.70  ? 734  GLU   A OE2   1 
ATOM   4099  N  N     . ALA   C 3 442 ? 25.673  48.723  -18.980 1.00 57.37  ? 735  ALA   A N     1 
ATOM   4100  C  CA    . ALA   C 3 442 ? 26.228  47.666  -18.149 1.00 57.58  ? 735  ALA   A CA    1 
ATOM   4101  C  C     . ALA   C 3 442 ? 25.115  46.966  -17.369 1.00 58.67  ? 735  ALA   A C     1 
ATOM   4102  O  O     . ALA   C 3 442 ? 24.077  47.564  -17.080 1.00 65.14  ? 735  ALA   A O     1 
ATOM   4103  C  CB    . ALA   C 3 442 ? 27.273  48.229  -17.220 1.00 58.22  ? 735  ALA   A CB    1 
ATOM   4104  N  N     . ARG   C 3 443 ? 25.356  45.690  -17.027 1.00 64.52  ? 736  ARG   A N     1 
ATOM   4105  C  CA    . ARG   C 3 443 ? 24.351  44.822  -16.425 1.00 64.78  ? 736  ARG   A CA    1 
ATOM   4106  C  C     . ARG   C 3 443 ? 24.256  45.133  -14.932 1.00 59.77  ? 736  ARG   A C     1 
ATOM   4107  O  O     . ARG   C 3 443 ? 23.155  45.269  -14.413 1.00 55.60  ? 736  ARG   A O     1 
ATOM   4108  C  CB    . ARG   C 3 443 ? 24.674  43.342  -16.695 1.00 67.18  ? 736  ARG   A CB    1 
ATOM   4109  N  N     . VAL   C 3 444 ? 25.414  45.274  -14.266 1.00 63.10  ? 737  VAL   A N     1 
ATOM   4110  C  CA    . VAL   C 3 444 ? 25.479  45.668  -12.864 1.00 64.33  ? 737  VAL   A CA    1 
ATOM   4111  C  C     . VAL   C 3 444 ? 24.958  47.104  -12.726 1.00 69.19  ? 737  VAL   A C     1 
ATOM   4112  O  O     . VAL   C 3 444 ? 25.504  48.026  -13.331 1.00 65.35  ? 737  VAL   A O     1 
ATOM   4113  C  CB    . VAL   C 3 444 ? 26.913  45.546  -12.296 1.00 67.89  ? 737  VAL   A CB    1 
ATOM   4114  C  CG1   . VAL   C 3 444 ? 26.926  45.703  -10.780 1.00 64.75  ? 737  VAL   A CG1   1 
ATOM   4115  C  CG2   . VAL   C 3 444 ? 27.605  44.247  -12.686 1.00 65.99  ? 737  VAL   A CG2   1 
ATOM   4116  N  N     . LYS   C 3 445 ? 23.920  47.292  -11.896 1.00 71.84  ? 738  LYS   A N     1 
ATOM   4117  C  CA    . LYS   C 3 445 ? 23.219  48.562  -11.761 1.00 69.60  ? 738  LYS   A CA    1 
ATOM   4118  C  C     . LYS   C 3 445 ? 24.173  49.693  -11.366 1.00 65.76  ? 738  LYS   A C     1 
ATOM   4119  O  O     . LYS   C 3 445 ? 24.139  50.776  -11.947 1.00 58.32  ? 738  LYS   A O     1 
ATOM   4120  C  CB    . LYS   C 3 445 ? 22.109  48.438  -10.711 1.00 75.20  ? 738  LYS   A CB    1 
ATOM   4121  C  CG    . LYS   C 3 445 ? 21.368  49.734  -10.411 1.00 80.97  ? 738  LYS   A CG    1 
ATOM   4122  C  CD    . LYS   C 3 445 ? 20.154  49.560  -9.543  1.00 84.79  ? 738  LYS   A CD    1 
ATOM   4123  C  CE    . LYS   C 3 445 ? 19.217  50.746  -9.624  1.00 89.79  ? 738  LYS   A CE    1 
ATOM   4124  N  NZ    . LYS   C 3 445 ? 18.020  50.548  -8.772  1.00 93.18  ? 738  LYS   A NZ    1 
ATOM   4125  N  N     . SER   C 3 446 ? 25.011  49.435  -10.358 1.00 62.25  ? 739  SER   A N     1 
ATOM   4126  C  CA    . SER   C 3 446 ? 25.877  50.447  -9.773  1.00 59.75  ? 739  SER   A CA    1 
ATOM   4127  C  C     . SER   C 3 446 ? 26.914  50.941  -10.783 1.00 55.44  ? 739  SER   A C     1 
ATOM   4128  O  O     . SER   C 3 446 ? 27.322  52.093  -10.725 1.00 53.21  ? 739  SER   A O     1 
ATOM   4129  C  CB    . SER   C 3 446 ? 26.554  49.910  -8.533  1.00 55.45  ? 739  SER   A CB    1 
ATOM   4130  O  OG    . SER   C 3 446 ? 27.464  48.881  -8.891  1.00 52.15  ? 739  SER   A OG    1 
ATOM   4131  N  N     . VAL   C 3 447 ? 27.371  50.051  -11.671 1.00 56.54  ? 740  VAL   A N     1 
ATOM   4132  C  CA    . VAL   C 3 447 ? 28.356  50.386  -12.690 1.00 54.86  ? 740  VAL   A CA    1 
ATOM   4133  C  C     . VAL   C 3 447 ? 27.679  51.185  -13.819 1.00 50.30  ? 740  VAL   A C     1 
ATOM   4134  O  O     . VAL   C 3 447 ? 28.256  52.139  -14.341 1.00 44.85  ? 740  VAL   A O     1 
ATOM   4135  C  CB    . VAL   C 3 447 ? 29.067  49.107  -13.186 1.00 53.52  ? 740  VAL   A CB    1 
ATOM   4136  C  CG1   . VAL   C 3 447 ? 29.945  49.353  -14.406 1.00 56.56  ? 740  VAL   A CG1   1 
ATOM   4137  C  CG2   . VAL   C 3 447 ? 29.887  48.459  -12.081 1.00 53.25  ? 740  VAL   A CG2   1 
ATOM   4138  N  N     . ARG   C 3 448 ? 26.438  50.822  -14.162 1.00 43.25  ? 741  ARG   A N     1 
ATOM   4139  C  CA    . ARG   C 3 448 ? 25.658  51.551  -15.146 1.00 45.24  ? 741  ARG   A CA    1 
ATOM   4140  C  C     . ARG   C 3 448 ? 25.391  52.976  -14.650 1.00 46.21  ? 741  ARG   A C     1 
ATOM   4141  O  O     . ARG   C 3 448 ? 25.555  53.938  -15.398 1.00 47.08  ? 741  ARG   A O     1 
ATOM   4142  C  CB    . ARG   C 3 448 ? 24.336  50.824  -15.423 1.00 43.61  ? 741  ARG   A CB    1 
ATOM   4143  C  CG    . ARG   C 3 448 ? 23.476  51.481  -16.496 1.00 48.56  ? 741  ARG   A CG    1 
ATOM   4144  C  CD    . ARG   C 3 448 ? 22.187  50.752  -16.812 1.00 53.26  ? 741  ARG   A CD    1 
ATOM   4145  N  NE    . ARG   C 3 448 ? 21.291  50.650  -15.664 1.00 61.17  ? 741  ARG   A NE    1 
ATOM   4146  C  CZ    . ARG   C 3 448 ? 21.102  49.542  -14.941 1.00 67.79  ? 741  ARG   A CZ    1 
ATOM   4147  N  NH1   . ARG   C 3 448 ? 21.789  48.432  -15.184 1.00 56.85  ? 741  ARG   A NH1   1 
ATOM   4148  N  NH2   . ARG   C 3 448 ? 20.231  49.560  -13.946 1.00 72.79  ? 741  ARG   A NH2   1 
ATOM   4149  N  N     . GLN   C 3 449 ? 24.965  53.094  -13.386 1.00 41.44  ? 742  GLN   A N     1 
ATOM   4150  C  CA    . GLN   C 3 449 ? 24.481  54.346  -12.832 1.00 41.43  ? 742  GLN   A CA    1 
ATOM   4151  C  C     . GLN   C 3 449 ? 25.641  55.317  -12.703 1.00 39.11  ? 742  GLN   A C     1 
ATOM   4152  O  O     . GLN   C 3 449 ? 25.471  56.504  -12.954 1.00 39.22  ? 742  GLN   A O     1 
ATOM   4153  C  CB    . GLN   C 3 449 ? 23.764  54.130  -11.495 1.00 43.54  ? 742  GLN   A CB    1 
ATOM   4154  C  CG    . GLN   C 3 449 ? 22.348  53.588  -11.689 1.00 47.64  ? 742  GLN   A CG    1 
ATOM   4155  C  CD    . GLN   C 3 449 ? 21.487  53.667  -10.452 1.00 49.10  ? 742  GLN   A CD    1 
ATOM   4156  O  OE1   . GLN   C 3 449 ? 21.949  53.415  -9.341  1.00 50.59  ? 742  GLN   A OE1   1 
ATOM   4157  N  NE2   . GLN   C 3 449 ? 20.223  54.005  -10.649 1.00 43.26  ? 742  GLN   A NE2   1 
ATOM   4158  N  N     . ALA   C 3 450 ? 26.812  54.782  -12.355 1.00 35.22  ? 743  ALA   A N     1 
ATOM   4159  C  CA    . ALA   C 3 450 ? 28.026  55.566  -12.281 1.00 38.46  ? 743  ALA   A CA    1 
ATOM   4160  C  C     . ALA   C 3 450 ? 28.337  56.176  -13.643 1.00 38.28  ? 743  ALA   A C     1 
ATOM   4161  O  O     . ALA   C 3 450 ? 28.625  57.367  -13.730 1.00 41.11  ? 743  ALA   A O     1 
ATOM   4162  C  CB    . ALA   C 3 450 ? 29.160  54.697  -11.792 1.00 41.70  ? 743  ALA   A CB    1 
ATOM   4163  N  N     . ALA   C 3 451 ? 28.287  55.330  -14.685 1.00 36.87  ? 744  ALA   A N     1 
ATOM   4164  C  CA    . ALA   C 3 451 ? 28.563  55.734  -16.053 1.00 34.90  ? 744  ALA   A CA    1 
ATOM   4165  C  C     . ALA   C 3 451 ? 27.620  56.857  -16.463 1.00 35.44  ? 744  ALA   A C     1 
ATOM   4166  O  O     . ALA   C 3 451 ? 28.058  57.837  -17.052 1.00 36.31  ? 744  ALA   A O     1 
ATOM   4167  C  CB    . ALA   C 3 451 ? 28.398  54.553  -16.974 1.00 36.86  ? 744  ALA   A CB    1 
ATOM   4168  N  N     . GLU   C 3 452 ? 26.336  56.690  -16.111 1.00 32.46  ? 745  GLU   A N     1 
ATOM   4169  C  CA    . GLU   C 3 452 ? 25.299  57.677  -16.341 1.00 34.91  ? 745  GLU   A CA    1 
ATOM   4170  C  C     . GLU   C 3 452 ? 25.672  59.033  -15.736 1.00 35.27  ? 745  GLU   A C     1 
ATOM   4171  O  O     . GLU   C 3 452 ? 25.541  60.046  -16.425 1.00 33.08  ? 745  GLU   A O     1 
ATOM   4172  C  CB    . GLU   C 3 452 ? 23.959  57.164  -15.796 1.00 37.42  ? 745  GLU   A CB    1 
ATOM   4173  C  CG    . GLU   C 3 452 ? 23.340  56.045  -16.646 1.00 38.65  ? 745  GLU   A CG    1 
ATOM   4174  C  CD    . GLU   C 3 452 ? 22.012  55.472  -16.150 1.00 38.09  ? 745  GLU   A CD    1 
ATOM   4175  O  OE1   . GLU   C 3 452 ? 21.640  55.752  -15.003 1.00 36.07  ? 745  GLU   A OE1   1 
ATOM   4176  O  OE2   . GLU   C 3 452 ? 21.338  54.758  -16.925 1.00 40.65  ? 745  GLU   A OE2   1 
ATOM   4177  N  N     . ARG   C 3 453 ? 26.127  59.054  -14.468 1.00 35.17  ? 746  ARG   A N     1 
ATOM   4178  C  CA    . ARG   C 3 453 ? 26.431  60.305  -13.778 1.00 35.43  ? 746  ARG   A CA    1 
ATOM   4179  C  C     . ARG   C 3 453 ? 27.573  61.029  -14.484 1.00 34.45  ? 746  ARG   A C     1 
ATOM   4180  O  O     . ARG   C 3 453 ? 27.485  62.242  -14.710 1.00 31.65  ? 746  ARG   A O     1 
ATOM   4181  C  CB    . ARG   C 3 453 ? 26.731  60.070  -12.295 1.00 34.95  ? 746  ARG   A CB    1 
ATOM   4182  C  CG    . ARG   C 3 453 ? 25.515  59.589  -11.517 1.00 35.62  ? 746  ARG   A CG    1 
ATOM   4183  C  CD    . ARG   C 3 453 ? 25.746  59.499  -10.025 1.00 37.89  ? 746  ARG   A CD    1 
ATOM   4184  N  NE    . ARG   C 3 453 ? 26.844  58.612  -9.685  1.00 40.18  ? 746  ARG   A NE    1 
ATOM   4185  C  CZ    . ARG   C 3 453 ? 26.687  57.343  -9.316  1.00 42.86  ? 746  ARG   A CZ    1 
ATOM   4186  N  NH1   . ARG   C 3 453 ? 25.496  56.772  -9.367  1.00 36.68  ? 746  ARG   A NH1   1 
ATOM   4187  N  NH2   . ARG   C 3 453 ? 27.734  56.638  -8.934  1.00 43.33  ? 746  ARG   A NH2   1 
ATOM   4188  N  N     . ARG   C 3 454 ? 28.596  60.259  -14.896 1.00 33.99  ? 747  ARG   A N     1 
ATOM   4189  C  CA    . ARG   C 3 454 ? 29.706  60.792  -15.684 1.00 35.92  ? 747  ARG   A CA    1 
ATOM   4190  C  C     . ARG   C 3 454 ? 29.194  61.401  -16.990 1.00 39.66  ? 747  ARG   A C     1 
ATOM   4191  O  O     . ARG   C 3 454 ? 29.636  62.478  -17.387 1.00 41.54  ? 747  ARG   A O     1 
ATOM   4192  C  CB    . ARG   C 3 454 ? 30.756  59.713  -15.973 1.00 38.23  ? 747  ARG   A CB    1 
ATOM   4193  C  CG    . ARG   C 3 454 ? 31.452  59.181  -14.726 1.00 41.51  ? 747  ARG   A CG    1 
ATOM   4194  C  CD    . ARG   C 3 454 ? 32.752  58.434  -14.987 1.00 42.29  ? 747  ARG   A CD    1 
ATOM   4195  N  NE    . ARG   C 3 454 ? 32.558  57.073  -15.447 1.00 45.71  ? 747  ARG   A NE    1 
ATOM   4196  C  CZ    . ARG   C 3 454 ? 32.206  56.042  -14.683 1.00 47.81  ? 747  ARG   A CZ    1 
ATOM   4197  N  NH1   . ARG   C 3 454 ? 32.277  56.119  -13.370 1.00 51.97  ? 747  ARG   A NH1   1 
ATOM   4198  N  NH2   . ARG   C 3 454 ? 31.796  54.915  -15.234 1.00 50.74  ? 747  ARG   A NH2   1 
ATOM   4199  N  N     . ALA   C 3 455 ? 28.211  60.735  -17.612 1.00 39.25  ? 748  ALA   A N     1 
ATOM   4200  C  CA    . ALA   C 3 455 ? 27.753  61.094  -18.941 1.00 37.14  ? 748  ALA   A CA    1 
ATOM   4201  C  C     . ALA   C 3 455 ? 26.895  62.359  -18.939 1.00 33.34  ? 748  ALA   A C     1 
ATOM   4202  O  O     . ALA   C 3 455 ? 27.059  63.194  -19.819 1.00 38.19  ? 748  ALA   A O     1 
ATOM   4203  C  CB    . ALA   C 3 455 ? 27.031  59.919  -19.555 1.00 38.52  ? 748  ALA   A CB    1 
ATOM   4204  N  N     . PHE   C 3 456 ? 25.933  62.500  -18.023 1.00 31.19  ? 749  PHE   A N     1 
ATOM   4205  C  CA    . PHE   C 3 456 ? 25.064  63.672  -18.091 1.00 30.68  ? 749  PHE   A CA    1 
ATOM   4206  C  C     . PHE   C 3 456 ? 25.709  64.872  -17.394 1.00 30.43  ? 749  PHE   A C     1 
ATOM   4207  O  O     . PHE   C 3 456 ? 25.268  66.001  -17.592 1.00 31.27  ? 749  PHE   A O     1 
ATOM   4208  C  CB    . PHE   C 3 456 ? 23.630  63.367  -17.635 1.00 32.30  ? 749  PHE   A CB    1 
ATOM   4209  C  CG    . PHE   C 3 456 ? 23.360  63.192  -16.160 1.00 33.27  ? 749  PHE   A CG    1 
ATOM   4210  C  CD1   . PHE   C 3 456 ? 23.230  64.290  -15.319 1.00 32.54  ? 749  PHE   A CD1   1 
ATOM   4211  C  CD2   . PHE   C 3 456 ? 23.158  61.927  -15.627 1.00 34.83  ? 749  PHE   A CD2   1 
ATOM   4212  C  CE1   . PHE   C 3 456 ? 22.934  64.124  -13.977 1.00 32.73  ? 749  PHE   A CE1   1 
ATOM   4213  C  CE2   . PHE   C 3 456 ? 22.895  61.760  -14.273 1.00 34.15  ? 749  PHE   A CE2   1 
ATOM   4214  C  CZ    . PHE   C 3 456 ? 22.783  62.863  -13.453 1.00 33.32  ? 749  PHE   A CZ    1 
ATOM   4215  N  N     . ASN   C 3 457 ? 26.773  64.646  -16.619 1.00 27.23  ? 750  ASN   A N     1 
ATOM   4216  C  CA    . ASN   C 3 457 ? 27.529  65.749  -16.061 1.00 30.05  ? 750  ASN   A CA    1 
ATOM   4217  C  C     . ASN   C 3 457 ? 28.333  66.447  -17.161 1.00 30.40  ? 750  ASN   A C     1 
ATOM   4218  O  O     . ASN   C 3 457 ? 28.476  67.670  -17.144 1.00 32.39  ? 750  ASN   A O     1 
ATOM   4219  C  CB    . ASN   C 3 457 ? 28.468  65.292  -14.938 1.00 29.62  ? 750  ASN   A CB    1 
ATOM   4220  C  CG    . ASN   C 3 457 ? 29.383  66.408  -14.478 1.00 29.57  ? 750  ASN   A CG    1 
ATOM   4221  O  OD1   . ASN   C 3 457 ? 28.990  67.279  -13.702 1.00 34.24  ? 750  ASN   A OD1   1 
ATOM   4222  N  ND2   . ASN   C 3 457 ? 30.603  66.405  -14.968 1.00 29.60  ? 750  ASN   A ND2   1 
ATOM   4223  N  N     . MET   C 3 458 ? 28.864  65.676  -18.118 1.00 29.31  ? 751  MET   A N     1 
ATOM   4224  C  CA    . MET   C 3 458 ? 29.921  66.190  -18.976 1.00 29.75  ? 751  MET   A CA    1 
ATOM   4225  C  C     . MET   C 3 458 ? 29.433  67.372  -19.811 1.00 29.63  ? 751  MET   A C     1 
ATOM   4226  O  O     . MET   C 3 458 ? 30.143  68.385  -19.916 1.00 30.51  ? 751  MET   A O     1 
ATOM   4227  C  CB    . MET   C 3 458 ? 30.509  65.120  -19.905 1.00 28.55  ? 751  MET   A CB    1 
ATOM   4228  C  CG    . MET   C 3 458 ? 31.582  65.665  -20.840 1.00 27.63  ? 751  MET   A CG    1 
ATOM   4229  S  SD    . MET   C 3 458 ? 31.012  65.896  -22.518 1.00 30.98  ? 751  MET   A SD    1 
ATOM   4230  C  CE    . MET   C 3 458 ? 32.526  66.521  -23.259 1.00 28.35  ? 751  MET   A CE    1 
ATOM   4231  N  N     . PRO   C 3 459 ? 28.257  67.287  -20.478 1.00 27.14  ? 752  PRO   A N     1 
ATOM   4232  C  CA    . PRO   C 3 459 ? 27.803  68.383  -21.334 1.00 26.04  ? 752  PRO   A CA    1 
ATOM   4233  C  C     . PRO   C 3 459 ? 27.713  69.714  -20.590 1.00 28.31  ? 752  PRO   A C     1 
ATOM   4234  O  O     . PRO   C 3 459 ? 27.913  70.768  -21.191 1.00 31.37  ? 752  PRO   A O     1 
ATOM   4235  C  CB    . PRO   C 3 459 ? 26.413  67.935  -21.813 1.00 26.09  ? 752  PRO   A CB    1 
ATOM   4236  C  CG    . PRO   C 3 459 ? 26.446  66.426  -21.707 1.00 25.20  ? 752  PRO   A CG    1 
ATOM   4237  C  CD    . PRO   C 3 459 ? 27.349  66.133  -20.522 1.00 26.65  ? 752  PRO   A CD    1 
ATOM   4238  N  N     . VAL   C 3 460 ? 27.418  69.657  -19.282 1.00 26.68  ? 753  VAL   A N     1 
ATOM   4239  C  CA    . VAL   C 3 460 ? 27.311  70.859  -18.483 1.00 29.50  ? 753  VAL   A CA    1 
ATOM   4240  C  C     . VAL   C 3 460 ? 28.716  71.379  -18.163 1.00 28.47  ? 753  VAL   A C     1 
ATOM   4241  O  O     . VAL   C 3 460 ? 29.034  72.537  -18.427 1.00 29.70  ? 753  VAL   A O     1 
ATOM   4242  C  CB    . VAL   C 3 460 ? 26.490  70.615  -17.196 1.00 31.87  ? 753  VAL   A CB    1 
ATOM   4243  C  CG1   . VAL   C 3 460 ? 26.363  71.892  -16.366 1.00 31.65  ? 753  VAL   A CG1   1 
ATOM   4244  C  CG2   . VAL   C 3 460 ? 25.107  70.065  -17.496 1.00 32.18  ? 753  VAL   A CG2   1 
ATOM   4245  N  N     . GLN   C 3 461 ? 29.549  70.519  -17.573 1.00 27.34  ? 754  GLN   A N     1 
ATOM   4246  C  CA    . GLN   C 3 461 ? 30.897  70.899  -17.177 1.00 28.81  ? 754  GLN   A CA    1 
ATOM   4247  C  C     . GLN   C 3 461 ? 31.714  71.333  -18.402 1.00 27.89  ? 754  GLN   A C     1 
ATOM   4248  O  O     . GLN   C 3 461 ? 32.470  72.315  -18.347 1.00 31.81  ? 754  GLN   A O     1 
ATOM   4249  C  CB    . GLN   C 3 461 ? 31.554  69.733  -16.438 1.00 28.03  ? 754  GLN   A CB    1 
ATOM   4250  C  CG    . GLN   C 3 461 ? 32.919  70.087  -15.884 1.00 31.62  ? 754  GLN   A CG    1 
ATOM   4251  C  CD    . GLN   C 3 461 ? 33.519  69.026  -15.003 1.00 30.78  ? 754  GLN   A CD    1 
ATOM   4252  O  OE1   . GLN   C 3 461 ? 32.856  68.437  -14.151 1.00 34.05  ? 754  GLN   A OE1   1 
ATOM   4253  N  NE2   . GLN   C 3 461 ? 34.789  68.770  -15.238 1.00 29.96  ? 754  GLN   A NE2   1 
ATOM   4254  N  N     . GLY   C 3 462 ? 31.537  70.598  -19.500 1.00 25.50  ? 755  GLY   A N     1 
ATOM   4255  C  CA    . GLY   C 3 462 ? 32.243  70.856  -20.753 1.00 26.15  ? 755  GLY   A CA    1 
ATOM   4256  C  C     . GLY   C 3 462 ? 31.750  72.098  -21.495 1.00 24.41  ? 755  GLY   A C     1 
ATOM   4257  O  O     . GLY   C 3 462 ? 32.553  72.843  -22.059 1.00 28.59  ? 755  GLY   A O     1 
ATOM   4258  N  N     . THR   C 3 463 ? 30.433  72.316  -21.531 1.00 24.55  ? 756  THR   A N     1 
ATOM   4259  C  CA    . THR   C 3 463 ? 29.910  73.525  -22.163 1.00 26.19  ? 756  THR   A CA    1 
ATOM   4260  C  C     . THR   C 3 463 ? 30.456  74.763  -21.443 1.00 26.48  ? 756  THR   A C     1 
ATOM   4261  O  O     . THR   C 3 463 ? 30.898  75.713  -22.069 1.00 27.51  ? 756  THR   A O     1 
ATOM   4262  C  CB    . THR   C 3 463 ? 28.379  73.515  -22.221 1.00 25.59  ? 756  THR   A CB    1 
ATOM   4263  O  OG1   . THR   C 3 463 ? 27.947  72.480  -23.126 1.00 24.97  ? 756  THR   A OG1   1 
ATOM   4264  C  CG2   . THR   C 3 463 ? 27.847  74.863  -22.645 1.00 25.06  ? 756  THR   A CG2   1 
ATOM   4265  N  N     . ALA   C 3 464 ? 30.468  74.721  -20.108 1.00 27.20  ? 757  ALA   A N     1 
ATOM   4266  C  CA    . ALA   C 3 464 ? 31.006  75.798  -19.292 1.00 26.44  ? 757  ALA   A CA    1 
ATOM   4267  C  C     . ALA   C 3 464 ? 32.484  76.044  -19.587 1.00 26.58  ? 757  ALA   A C     1 
ATOM   4268  O  O     . ALA   C 3 464 ? 32.919  77.195  -19.648 1.00 32.41  ? 757  ALA   A O     1 
ATOM   4269  C  CB    . ALA   C 3 464 ? 30.780  75.472  -17.834 1.00 26.36  ? 757  ALA   A CB    1 
ATOM   4270  N  N     . ALA   C 3 465 ? 33.260  74.964  -19.754 1.00 26.96  ? 758  ALA   A N     1 
ATOM   4271  C  CA    . ALA   C 3 465 ? 34.676  75.071  -20.082 1.00 24.95  ? 758  ALA   A CA    1 
ATOM   4272  C  C     . ALA   C 3 465 ? 34.863  75.686  -21.470 1.00 26.77  ? 758  ALA   A C     1 
ATOM   4273  O  O     . ALA   C 3 465 ? 35.734  76.524  -21.663 1.00 29.51  ? 758  ALA   A O     1 
ATOM   4274  C  CB    . ALA   C 3 465 ? 35.315  73.703  -20.012 1.00 25.35  ? 758  ALA   A CB    1 
ATOM   4275  N  N     . ASP   C 3 466 ? 34.062  75.237  -22.436 1.00 26.71  ? 759  ASP   A N     1 
ATOM   4276  C  CA    . ASP   C 3 466 ? 34.098  75.754  -23.800 1.00 28.55  ? 759  ASP   A CA    1 
ATOM   4277  C  C     . ASP   C 3 466 ? 33.829  77.260  -23.805 1.00 27.75  ? 759  ASP   A C     1 
ATOM   4278  O  O     . ASP   C 3 466 ? 34.532  78.001  -24.477 1.00 27.81  ? 759  ASP   A O     1 
ATOM   4279  C  CB    . ASP   C 3 466 ? 33.066  75.042  -24.688 1.00 29.15  ? 759  ASP   A CB    1 
ATOM   4280  C  CG    . ASP   C 3 466 ? 33.346  73.580  -25.034 1.00 30.75  ? 759  ASP   A CG    1 
ATOM   4281  O  OD1   . ASP   C 3 466 ? 34.499  73.133  -24.860 1.00 33.46  ? 759  ASP   A OD1   1 
ATOM   4282  O  OD2   . ASP   C 3 466 ? 32.388  72.885  -25.474 1.00 34.14  ? 759  ASP   A OD2   1 
ATOM   4283  N  N     . LEU   C 3 467 ? 32.841  77.707  -23.016 1.00 28.33  ? 760  LEU   A N     1 
ATOM   4284  C  CA    . LEU   C 3 467 ? 32.451  79.113  -22.973 1.00 30.08  ? 760  LEU   A CA    1 
ATOM   4285  C  C     . LEU   C 3 467 ? 33.558  79.956  -22.351 1.00 29.73  ? 760  LEU   A C     1 
ATOM   4286  O  O     . LEU   C 3 467 ? 33.822  81.056  -22.815 1.00 30.33  ? 760  LEU   A O     1 
ATOM   4287  C  CB    . LEU   C 3 467 ? 31.154  79.271  -22.171 1.00 31.16  ? 760  LEU   A CB    1 
ATOM   4288  C  CG    . LEU   C 3 467 ? 29.863  78.784  -22.834 1.00 32.20  ? 760  LEU   A CG    1 
ATOM   4289  C  CD1   . LEU   C 3 467 ? 28.714  78.819  -21.825 1.00 30.75  ? 760  LEU   A CD1   1 
ATOM   4290  C  CD2   . LEU   C 3 467 ? 29.503  79.634  -24.041 1.00 30.96  ? 760  LEU   A CD2   1 
ATOM   4291  N  N     . MET   C 3 468 ? 34.204  79.437  -21.298 1.00 30.41  ? 761  MET   A N     1 
ATOM   4292  C  CA    . MET   C 3 468 ? 35.298  80.152  -20.667 1.00 29.51  ? 761  MET   A CA    1 
ATOM   4293  C  C     . MET   C 3 468 ? 36.473  80.293  -21.638 1.00 28.59  ? 761  MET   A C     1 
ATOM   4294  O  O     . MET   C 3 468 ? 37.089  81.357  -21.703 1.00 30.01  ? 761  MET   A O     1 
ATOM   4295  C  CB    . MET   C 3 468 ? 35.749  79.449  -19.376 1.00 28.86  ? 761  MET   A CB    1 
ATOM   4296  C  CG    . MET   C 3 468 ? 36.986  80.056  -18.726 1.00 26.55  ? 761  MET   A CG    1 
ATOM   4297  S  SD    . MET   C 3 468 ? 36.876  81.853  -18.458 1.00 28.85  ? 761  MET   A SD    1 
ATOM   4298  C  CE    . MET   C 3 468 ? 36.193  81.850  -16.798 1.00 29.84  ? 761  MET   A CE    1 
ATOM   4299  N  N     . LYS   C 3 469 ? 36.808  79.210  -22.350 1.00 27.48  ? 762  LYS   A N     1 
ATOM   4300  C  CA    . LYS   C 3 469 ? 37.928  79.193  -23.284 1.00 28.10  ? 762  LYS   A CA    1 
ATOM   4301  C  C     . LYS   C 3 469 ? 37.718  80.188  -24.425 1.00 28.10  ? 762  LYS   A C     1 
ATOM   4302  O  O     . LYS   C 3 469 ? 38.661  80.788  -24.924 1.00 32.63  ? 762  LYS   A O     1 
ATOM   4303  C  CB    . LYS   C 3 469 ? 38.126  77.802  -23.892 1.00 27.13  ? 762  LYS   A CB    1 
ATOM   4304  C  CG    . LYS   C 3 469 ? 38.739  76.760  -22.970 1.00 26.75  ? 762  LYS   A CG    1 
ATOM   4305  C  CD    . LYS   C 3 469 ? 38.818  75.383  -23.588 1.00 28.55  ? 762  LYS   A CD    1 
ATOM   4306  C  CE    . LYS   C 3 469 ? 39.645  74.447  -22.739 1.00 31.03  ? 762  LYS   A CE    1 
ATOM   4307  N  NZ    . LYS   C 3 469 ? 39.675  73.068  -23.274 1.00 32.75  ? 762  LYS   A NZ    1 
ATOM   4308  N  N     . LEU   C 3 470 ? 36.475  80.335  -24.860 1.00 30.46  ? 763  LEU   A N     1 
ATOM   4309  C  CA    . LEU   C 3 470 ? 36.128  81.255  -25.933 1.00 33.77  ? 763  LEU   A CA    1 
ATOM   4310  C  C     . LEU   C 3 470 ? 36.252  82.700  -25.436 1.00 32.58  ? 763  LEU   A C     1 
ATOM   4311  O  O     . LEU   C 3 470 ? 36.716  83.577  -26.162 1.00 34.05  ? 763  LEU   A O     1 
ATOM   4312  C  CB    . LEU   C 3 470 ? 34.704  80.861  -26.335 1.00 38.97  ? 763  LEU   A CB    1 
ATOM   4313  C  CG    . LEU   C 3 470 ? 34.149  81.371  -27.661 1.00 45.75  ? 763  LEU   A CG    1 
ATOM   4314  C  CD1   . LEU   C 3 470 ? 35.161  81.268  -28.806 1.00 48.39  ? 763  LEU   A CD1   1 
ATOM   4315  C  CD2   . LEU   C 3 470 ? 32.876  80.594  -27.973 1.00 46.37  ? 763  LEU   A CD2   1 
ATOM   4316  N  N     . ALA   C 3 471 ? 35.859  82.930  -24.173 1.00 28.63  ? 764  ALA   A N     1 
ATOM   4317  C  CA    . ALA   C 3 471 ? 36.044  84.205  -23.505 1.00 29.20  ? 764  ALA   A CA    1 
ATOM   4318  C  C     . ALA   C 3 471 ? 37.527  84.577  -23.412 1.00 31.28  ? 764  ALA   A C     1 
ATOM   4319  O  O     . ALA   C 3 471 ? 37.901  85.720  -23.677 1.00 33.19  ? 764  ALA   A O     1 
ATOM   4320  C  CB    . ALA   C 3 471 ? 35.416  84.141  -22.138 1.00 30.40  ? 764  ALA   A CB    1 
ATOM   4321  N  N     . MET   C 3 472 ? 38.376  83.615  -23.026 1.00 29.63  ? 765  MET   A N     1 
ATOM   4322  C  CA    . MET   C 3 472 ? 39.815  83.850  -22.916 1.00 29.30  ? 765  MET   A CA    1 
ATOM   4323  C  C     . MET   C 3 472 ? 40.421  84.223  -24.271 1.00 28.69  ? 765  MET   A C     1 
ATOM   4324  O  O     . MET   C 3 472 ? 41.199  85.172  -24.358 1.00 30.51  ? 765  MET   A O     1 
ATOM   4325  C  CB    . MET   C 3 472 ? 40.510  82.600  -22.367 1.00 28.66  ? 765  MET   A CB    1 
ATOM   4326  C  CG    . MET   C 3 472 ? 40.145  82.336  -20.930 1.00 27.29  ? 765  MET   A CG    1 
ATOM   4327  S  SD    . MET   C 3 472 ? 40.709  80.760  -20.325 1.00 28.72  ? 765  MET   A SD    1 
ATOM   4328  C  CE    . MET   C 3 472 ? 42.423  81.196  -20.028 1.00 29.50  ? 765  MET   A CE    1 
ATOM   4329  N  N     . VAL   C 3 473 ? 40.097  83.451  -25.317 1.00 31.73  ? 766  VAL   A N     1 
ATOM   4330  C  CA    . VAL   C 3 473 ? 40.642  83.652  -26.657 1.00 32.61  ? 766  VAL   A CA    1 
ATOM   4331  C  C     . VAL   C 3 473 ? 40.233  85.026  -27.197 1.00 33.89  ? 766  VAL   A C     1 
ATOM   4332  O  O     . VAL   C 3 473 ? 40.997  85.698  -27.891 1.00 38.96  ? 766  VAL   A O     1 
ATOM   4333  C  CB    . VAL   C 3 473 ? 40.149  82.529  -27.589 1.00 34.04  ? 766  VAL   A CB    1 
ATOM   4334  C  CG1   . VAL   C 3 473 ? 40.291  82.886  -29.074 1.00 33.87  ? 766  VAL   A CG1   1 
ATOM   4335  C  CG2   . VAL   C 3 473 ? 40.821  81.204  -27.266 1.00 32.67  ? 766  VAL   A CG2   1 
ATOM   4336  N  N     . LYS   C 3 474 ? 39.015  85.441  -26.862 1.00 33.69  ? 767  LYS   A N     1 
ATOM   4337  C  CA    . LYS   C 3 474 ? 38.463  86.724  -27.274 1.00 35.61  ? 767  LYS   A CA    1 
ATOM   4338  C  C     . LYS   C 3 474 ? 39.032  87.881  -26.453 1.00 33.25  ? 767  LYS   A C     1 
ATOM   4339  O  O     . LYS   C 3 474 ? 39.353  88.923  -27.001 1.00 35.09  ? 767  LYS   A O     1 
ATOM   4340  C  CB    . LYS   C 3 474 ? 36.946  86.623  -27.143 1.00 38.90  ? 767  LYS   A CB    1 
ATOM   4341  C  CG    . LYS   C 3 474 ? 36.146  87.739  -27.782 1.00 50.61  ? 767  LYS   A CG    1 
ATOM   4342  C  CD    . LYS   C 3 474 ? 34.653  87.414  -27.757 1.00 54.84  ? 767  LYS   A CD    1 
ATOM   4343  C  CE    . LYS   C 3 474 ? 33.769  88.573  -28.166 1.00 58.97  ? 767  LYS   A CE    1 
ATOM   4344  N  NZ    . LYS   C 3 474 ? 32.380  88.094  -28.369 1.00 61.33  ? 767  LYS   A NZ    1 
ATOM   4345  N  N     . LEU   C 3 475 ? 39.164  87.691  -25.141 1.00 32.78  ? 768  LEU   A N     1 
ATOM   4346  C  CA    . LEU   C 3 475 ? 39.632  88.719  -24.227 1.00 33.01  ? 768  LEU   A CA    1 
ATOM   4347  C  C     . LEU   C 3 475 ? 41.141  88.958  -24.330 1.00 32.93  ? 768  LEU   A C     1 
ATOM   4348  O  O     . LEU   C 3 475 ? 41.595  90.095  -24.256 1.00 35.55  ? 768  LEU   A O     1 
ATOM   4349  C  CB    . LEU   C 3 475 ? 39.261  88.276  -22.810 1.00 34.51  ? 768  LEU   A CB    1 
ATOM   4350  C  CG    . LEU   C 3 475 ? 39.601  89.266  -21.702 1.00 36.28  ? 768  LEU   A CG    1 
ATOM   4351  C  CD1   . LEU   C 3 475 ? 39.032  90.655  -22.002 1.00 37.88  ? 768  LEU   A CD1   1 
ATOM   4352  C  CD2   . LEU   C 3 475 ? 39.098  88.754  -20.364 1.00 34.37  ? 768  LEU   A CD2   1 
ATOM   4353  N  N     . PHE   C 3 476 ? 41.943  87.906  -24.462 1.00 31.92  ? 769  PHE   A N     1 
ATOM   4354  C  CA    . PHE   C 3 476 ? 43.373  88.065  -24.269 1.00 34.81  ? 769  PHE   A CA    1 
ATOM   4355  C  C     . PHE   C 3 476 ? 43.973  89.148  -25.173 1.00 38.95  ? 769  PHE   A C     1 
ATOM   4356  O  O     . PHE   C 3 476 ? 44.737  89.987  -24.687 1.00 42.24  ? 769  PHE   A O     1 
ATOM   4357  C  CB    . PHE   C 3 476 ? 44.137  86.759  -24.482 1.00 36.52  ? 769  PHE   A CB    1 
ATOM   4358  C  CG    . PHE   C 3 476 ? 45.613  86.911  -24.229 1.00 35.40  ? 769  PHE   A CG    1 
ATOM   4359  C  CD1   . PHE   C 3 476 ? 46.093  87.092  -22.941 1.00 42.10  ? 769  PHE   A CD1   1 
ATOM   4360  C  CD2   . PHE   C 3 476 ? 46.516  86.926  -25.274 1.00 39.44  ? 769  PHE   A CD2   1 
ATOM   4361  C  CE1   . PHE   C 3 476 ? 47.453  87.241  -22.701 1.00 42.65  ? 769  PHE   A CE1   1 
ATOM   4362  C  CE2   . PHE   C 3 476 ? 47.874  87.086  -25.037 1.00 40.23  ? 769  PHE   A CE2   1 
ATOM   4363  C  CZ    . PHE   C 3 476 ? 48.341  87.250  -23.755 1.00 39.58  ? 769  PHE   A CZ    1 
ATOM   4364  N  N     . PRO   C 3 477 ? 43.718  89.157  -26.504 1.00 40.02  ? 770  PRO   A N     1 
ATOM   4365  C  CA    . PRO   C 3 477 ? 44.347  90.140  -27.391 1.00 40.55  ? 770  PRO   A CA    1 
ATOM   4366  C  C     . PRO   C 3 477 ? 44.021  91.587  -27.023 1.00 40.39  ? 770  PRO   A C     1 
ATOM   4367  O  O     . PRO   C 3 477 ? 44.828  92.469  -27.270 1.00 47.76  ? 770  PRO   A O     1 
ATOM   4368  C  CB    . PRO   C 3 477 ? 43.781  89.829  -28.793 1.00 42.02  ? 770  PRO   A CB    1 
ATOM   4369  C  CG    . PRO   C 3 477 ? 43.206  88.418  -28.677 1.00 42.30  ? 770  PRO   A CG    1 
ATOM   4370  C  CD    . PRO   C 3 477 ? 42.799  88.261  -27.229 1.00 40.89  ? 770  PRO   A CD    1 
ATOM   4371  N  N     . ARG   C 3 478 ? 42.818  91.816  -26.477 1.00 44.05  ? 771  ARG   A N     1 
ATOM   4372  C  CA    . ARG   C 3 478 ? 42.348  93.124  -26.044 1.00 43.28  ? 771  ARG   A CA    1 
ATOM   4373  C  C     . ARG   C 3 478 ? 43.037  93.575  -24.753 1.00 42.77  ? 771  ARG   A C     1 
ATOM   4374  O  O     . ARG   C 3 478 ? 43.143  94.764  -24.501 1.00 45.65  ? 771  ARG   A O     1 
ATOM   4375  C  CB    . ARG   C 3 478 ? 40.836  93.078  -25.790 1.00 45.04  ? 771  ARG   A CB    1 
ATOM   4376  C  CG    . ARG   C 3 478 ? 39.956  93.676  -26.883 1.00 49.38  ? 771  ARG   A CG    1 
ATOM   4377  C  CD    . ARG   C 3 478 ? 39.966  92.988  -28.221 1.00 46.19  ? 771  ARG   A CD    1 
ATOM   4378  N  NE    . ARG   C 3 478 ? 41.123  93.293  -29.058 1.00 43.92  ? 771  ARG   A NE    1 
ATOM   4379  C  CZ    . ARG   C 3 478 ? 41.528  92.514  -30.063 1.00 42.33  ? 771  ARG   A CZ    1 
ATOM   4380  N  NH1   . ARG   C 3 478 ? 42.671  92.752  -30.684 1.00 41.64  ? 771  ARG   A NH1   1 
ATOM   4381  N  NH2   . ARG   C 3 478 ? 40.808  91.458  -30.408 1.00 38.06  ? 771  ARG   A NH2   1 
ATOM   4382  N  N     . LEU   C 3 479 ? 43.440  92.632  -23.892 1.00 46.19  ? 772  LEU   A N     1 
ATOM   4383  C  CA    . LEU   C 3 479 ? 44.154  92.970  -22.670 1.00 45.09  ? 772  LEU   A CA    1 
ATOM   4384  C  C     . LEU   C 3 479 ? 45.528  93.536  -23.020 1.00 47.54  ? 772  LEU   A C     1 
ATOM   4385  O  O     . LEU   C 3 479 ? 45.946  94.521  -22.423 1.00 49.32  ? 772  LEU   A O     1 
ATOM   4386  C  CB    . LEU   C 3 479 ? 44.301  91.731  -21.781 1.00 45.12  ? 772  LEU   A CB    1 
ATOM   4387  C  CG    . LEU   C 3 479 ? 43.015  91.193  -21.160 1.00 41.82  ? 772  LEU   A CG    1 
ATOM   4388  C  CD1   . LEU   C 3 479 ? 43.321  90.083  -20.168 1.00 43.44  ? 772  LEU   A CD1   1 
ATOM   4389  C  CD2   . LEU   C 3 479 ? 42.214  92.295  -20.490 1.00 41.65  ? 772  LEU   A CD2   1 
ATOM   4390  N  N     . GLU   C 3 480 ? 46.224  92.922  -23.986 1.00 53.18  ? 773  GLU   A N     1 
ATOM   4391  C  CA    . GLU   C 3 480 ? 47.572  93.351  -24.349 1.00 62.98  ? 773  GLU   A CA    1 
ATOM   4392  C  C     . GLU   C 3 480 ? 47.592  94.807  -24.826 1.00 62.24  ? 773  GLU   A C     1 
ATOM   4393  O  O     . GLU   C 3 480 ? 48.489  95.564  -24.466 1.00 59.92  ? 773  GLU   A O     1 
ATOM   4394  C  CB    . GLU   C 3 480 ? 48.166  92.444  -25.426 1.00 68.28  ? 773  GLU   A CB    1 
ATOM   4395  C  CG    . GLU   C 3 480 ? 48.470  91.034  -24.951 1.00 67.97  ? 773  GLU   A CG    1 
ATOM   4396  C  CD    . GLU   C 3 480 ? 49.165  90.196  -26.015 1.00 77.46  ? 773  GLU   A CD    1 
ATOM   4397  O  OE1   . GLU   C 3 480 ? 48.668  90.186  -27.175 1.00 71.21  ? 773  GLU   A OE1   1 
ATOM   4398  O  OE2   . GLU   C 3 480 ? 50.200  89.556  -25.691 1.00 82.67  ? 773  GLU   A OE2   1 
ATOM   4399  N  N     . GLU   C 3 481 ? 46.577  95.196  -25.608 1.00 65.03  ? 774  GLU   A N     1 
ATOM   4400  C  CA    . GLU   C 3 481 ? 46.436  96.553  -26.115 1.00 64.74  ? 774  GLU   A CA    1 
ATOM   4401  C  C     . GLU   C 3 481 ? 46.337  97.557  -24.965 1.00 60.06  ? 774  GLU   A C     1 
ATOM   4402  O  O     . GLU   C 3 481 ? 46.600  98.736  -25.154 1.00 62.20  ? 774  GLU   A O     1 
ATOM   4403  C  CB    . GLU   C 3 481 ? 45.178  96.667  -26.987 1.00 69.98  ? 774  GLU   A CB    1 
ATOM   4404  C  CG    . GLU   C 3 481 ? 45.192  95.804  -28.249 1.00 71.50  ? 774  GLU   A CG    1 
ATOM   4405  C  CD    . GLU   C 3 481 ? 43.853  95.650  -28.970 1.00 74.19  ? 774  GLU   A CD    1 
ATOM   4406  O  OE1   . GLU   C 3 481 ? 42.801  96.089  -28.419 1.00 63.32  ? 774  GLU   A OE1   1 
ATOM   4407  O  OE2   . GLU   C 3 481 ? 43.858  95.104  -30.103 1.00 71.49  ? 774  GLU   A OE2   1 
ATOM   4408  N  N     . MET   C 3 482 ? 45.892  97.097  -23.788 1.00 64.31  ? 775  MET   A N     1 
ATOM   4409  C  CA    . MET   C 3 482 ? 45.594  97.963  -22.656 1.00 57.88  ? 775  MET   A CA    1 
ATOM   4410  C  C     . MET   C 3 482 ? 46.691  97.865  -21.595 1.00 53.37  ? 775  MET   A C     1 
ATOM   4411  O  O     . MET   C 3 482 ? 46.504  98.380  -20.499 1.00 49.99  ? 775  MET   A O     1 
ATOM   4412  C  CB    . MET   C 3 482 ? 44.274  97.547  -21.995 1.00 60.50  ? 775  MET   A CB    1 
ATOM   4413  C  CG    . MET   C 3 482 ? 43.048  97.797  -22.847 1.00 67.54  ? 775  MET   A CG    1 
ATOM   4414  S  SD    . MET   C 3 482 ? 41.520  97.432  -21.937 1.00 72.22  ? 775  MET   A SD    1 
ATOM   4415  C  CE    . MET   C 3 482 ? 41.294  98.985  -21.073 1.00 67.78  ? 775  MET   A CE    1 
ATOM   4416  N  N     . GLY   C 3 483 ? 47.803  97.174  -21.907 1.00 54.84  ? 776  GLY   A N     1 
ATOM   4417  C  CA    . GLY   C 3 483 ? 48.878  96.932  -20.950 1.00 53.22  ? 776  GLY   A CA    1 
ATOM   4418  C  C     . GLY   C 3 483 ? 48.434  96.111  -19.732 1.00 52.47  ? 776  GLY   A C     1 
ATOM   4419  O  O     . GLY   C 3 483 ? 48.896  96.362  -18.623 1.00 50.77  ? 776  GLY   A O     1 
ATOM   4420  N  N     . ALA   C 3 484 ? 47.545  95.126  -19.947 1.00 44.37  ? 777  ALA   A N     1 
ATOM   4421  C  CA    . ALA   C 3 484 ? 47.051  94.270  -18.882 1.00 40.54  ? 777  ALA   A CA    1 
ATOM   4422  C  C     . ALA   C 3 484 ? 47.473  92.825  -19.141 1.00 38.69  ? 777  ALA   A C     1 
ATOM   4423  O  O     . ALA   C 3 484 ? 47.915  92.477  -20.242 1.00 35.61  ? 777  ALA   A O     1 
ATOM   4424  C  CB    . ALA   C 3 484 ? 45.558  94.391  -18.766 1.00 42.36  ? 777  ALA   A CB    1 
ATOM   4425  N  N     . ARG   C 3 485 ? 47.361  92.006  -18.091 1.00 35.10  ? 778  ARG   A N     1 
ATOM   4426  C  CA    . ARG   C 3 485 ? 47.826  90.631  -18.140 1.00 36.62  ? 778  ARG   A CA    1 
ATOM   4427  C  C     . ARG   C 3 485 ? 46.722  89.708  -17.657 1.00 36.33  ? 778  ARG   A C     1 
ATOM   4428  O  O     . ARG   C 3 485 ? 45.895  90.098  -16.833 1.00 35.74  ? 778  ARG   A O     1 
ATOM   4429  C  CB    . ARG   C 3 485 ? 49.019  90.405  -17.209 1.00 38.70  ? 778  ARG   A CB    1 
ATOM   4430  C  CG    . ARG   C 3 485 ? 50.256  91.229  -17.536 1.00 42.18  ? 778  ARG   A CG    1 
ATOM   4431  C  CD    . ARG   C 3 485 ? 51.139  91.297  -16.308 1.00 42.91  ? 778  ARG   A CD    1 
ATOM   4432  N  NE    . ARG   C 3 485 ? 52.284  92.181  -16.457 1.00 45.37  ? 778  ARG   A NE    1 
ATOM   4433  C  CZ    . ARG   C 3 485 ? 53.059  92.578  -15.451 1.00 46.25  ? 778  ARG   A CZ    1 
ATOM   4434  N  NH1   . ARG   C 3 485 ? 52.753  92.291  -14.196 1.00 43.03  ? 778  ARG   A NH1   1 
ATOM   4435  N  NH2   . ARG   C 3 485 ? 54.141  93.287  -15.708 1.00 46.80  ? 778  ARG   A NH2   1 
ATOM   4436  N  N     . MET   C 3 486 ? 46.771  88.479  -18.167 1.00 34.74  ? 779  MET   A N     1 
ATOM   4437  C  CA    . MET   C 3 486 ? 45.943  87.383  -17.714 1.00 33.32  ? 779  MET   A CA    1 
ATOM   4438  C  C     . MET   C 3 486 ? 46.833  86.459  -16.895 1.00 33.45  ? 779  MET   A C     1 
ATOM   4439  O  O     . MET   C 3 486 ? 47.810  85.935  -17.426 1.00 31.38  ? 779  MET   A O     1 
ATOM   4440  C  CB    . MET   C 3 486 ? 45.357  86.635  -18.922 1.00 32.98  ? 779  MET   A CB    1 
ATOM   4441  C  CG    . MET   C 3 486 ? 44.210  85.689  -18.563 1.00 35.89  ? 779  MET   A CG    1 
ATOM   4442  S  SD    . MET   C 3 486 ? 43.324  85.005  -20.011 1.00 40.16  ? 779  MET   A SD    1 
ATOM   4443  C  CE    . MET   C 3 486 ? 42.519  86.484  -20.626 1.00 38.06  ? 779  MET   A CE    1 
ATOM   4444  N  N     . LEU   C 3 487 ? 46.504  86.258  -15.607 1.00 32.71  ? 780  LEU   A N     1 
ATOM   4445  C  CA    . LEU   C 3 487 ? 47.372  85.476  -14.737 1.00 33.28  ? 780  LEU   A CA    1 
ATOM   4446  C  C     . LEU   C 3 487 ? 46.844  84.054  -14.553 1.00 33.18  ? 780  LEU   A C     1 
ATOM   4447  O  O     . LEU   C 3 487 ? 47.624  83.099  -14.653 1.00 33.97  ? 780  LEU   A O     1 
ATOM   4448  C  CB    . LEU   C 3 487 ? 47.498  86.173  -13.378 1.00 35.07  ? 780  LEU   A CB    1 
ATOM   4449  C  CG    . LEU   C 3 487 ? 48.006  87.616  -13.383 1.00 34.08  ? 780  LEU   A CG    1 
ATOM   4450  C  CD1   . LEU   C 3 487 ? 48.391  88.016  -11.972 1.00 36.14  ? 780  LEU   A CD1   1 
ATOM   4451  C  CD2   . LEU   C 3 487 ? 49.174  87.804  -14.335 1.00 33.71  ? 780  LEU   A CD2   1 
ATOM   4452  N  N     . LEU   C 3 488 ? 45.546  83.922  -14.217 1.00 32.97  ? 781  LEU   A N     1 
ATOM   4453  C  CA    . LEU   C 3 488 ? 44.984  82.636  -13.820 1.00 30.86  ? 781  LEU   A CA    1 
ATOM   4454  C  C     . LEU   C 3 488 ? 43.595  82.427  -14.405 1.00 31.82  ? 781  LEU   A C     1 
ATOM   4455  O  O     . LEU   C 3 488 ? 42.854  83.380  -14.639 1.00 30.08  ? 781  LEU   A O     1 
ATOM   4456  C  CB    . LEU   C 3 488 ? 44.895  82.546  -12.297 1.00 30.80  ? 781  LEU   A CB    1 
ATOM   4457  C  CG    . LEU   C 3 488 ? 46.196  82.775  -11.529 1.00 31.72  ? 781  LEU   A CG    1 
ATOM   4458  C  CD1   . LEU   C 3 488 ? 45.902  82.893  -10.041 1.00 34.54  ? 781  LEU   A CD1   1 
ATOM   4459  C  CD2   . LEU   C 3 488 ? 47.199  81.661  -11.762 1.00 33.84  ? 781  LEU   A CD2   1 
ATOM   4460  N  N     . GLN   C 3 489 ? 43.283  81.139  -14.623 1.00 32.59  ? 782  GLN   A N     1 
ATOM   4461  C  CA    . GLN   C 3 489 ? 41.934  80.651  -14.829 1.00 30.73  ? 782  GLN   A CA    1 
ATOM   4462  C  C     . GLN   C 3 489 ? 41.680  79.611  -13.749 1.00 30.53  ? 782  GLN   A C     1 
ATOM   4463  O  O     . GLN   C 3 489 ? 42.542  78.773  -13.478 1.00 30.53  ? 782  GLN   A O     1 
ATOM   4464  C  CB    . GLN   C 3 489 ? 41.764  80.111  -16.253 1.00 33.06  ? 782  GLN   A CB    1 
ATOM   4465  C  CG    . GLN   C 3 489 ? 40.336  79.668  -16.601 1.00 33.29  ? 782  GLN   A CG    1 
ATOM   4466  C  CD    . GLN   C 3 489 ? 40.178  78.169  -16.679 1.00 30.89  ? 782  GLN   A CD    1 
ATOM   4467  O  OE1   . GLN   C 3 489 ? 40.624  77.433  -15.805 1.00 33.92  ? 782  GLN   A OE1   1 
ATOM   4468  N  NE2   . GLN   C 3 489 ? 39.574  77.697  -17.750 1.00 31.43  ? 782  GLN   A NE2   1 
ATOM   4469  N  N     . VAL   C 3 490 ? 40.505  79.704  -13.110 1.00 29.41  ? 783  VAL   A N     1 
ATOM   4470  C  CA    . VAL   C 3 490 ? 40.099  78.721  -12.116 1.00 26.23  ? 783  VAL   A CA    1 
ATOM   4471  C  C     . VAL   C 3 490 ? 38.682  78.281  -12.471 1.00 25.43  ? 783  VAL   A C     1 
ATOM   4472  O  O     . VAL   C 3 490 ? 37.707  78.511  -11.751 1.00 27.94  ? 783  VAL   A O     1 
ATOM   4473  C  CB    . VAL   C 3 490 ? 40.268  79.253  -10.680 1.00 26.85  ? 783  VAL   A CB    1 
ATOM   4474  C  CG1   . VAL   C 3 490 ? 40.003  78.173  -9.653  1.00 27.47  ? 783  VAL   A CG1   1 
ATOM   4475  C  CG2   . VAL   C 3 490 ? 41.656  79.846  -10.463 1.00 26.09  ? 783  VAL   A CG2   1 
ATOM   4476  N  N     . HIS   C 3 491 ? 38.623  77.708  -13.672 1.00 26.37  ? 784  HIS   A N     1 
ATOM   4477  C  CA    . HIS   C 3 491 ? 37.452  77.094  -14.267 1.00 28.57  ? 784  HIS   A CA    1 
ATOM   4478  C  C     . HIS   C 3 491 ? 36.434  78.142  -14.709 1.00 28.40  ? 784  HIS   A C     1 
ATOM   4479  O  O     . HIS   C 3 491 ? 36.382  78.470  -15.878 1.00 36.73  ? 784  HIS   A O     1 
ATOM   4480  C  CB    . HIS   C 3 491 ? 36.905  76.037  -13.321 1.00 26.86  ? 784  HIS   A CB    1 
ATOM   4481  C  CG    . HIS   C 3 491 ? 37.949  75.025  -12.981 1.00 25.89  ? 784  HIS   A CG    1 
ATOM   4482  N  ND1   . HIS   C 3 491 ? 38.669  74.343  -13.922 1.00 25.66  ? 784  HIS   A ND1   1 
ATOM   4483  C  CD2   . HIS   C 3 491 ? 38.434  74.676  -11.753 1.00 26.23  ? 784  HIS   A CD2   1 
ATOM   4484  C  CE1   . HIS   C 3 491 ? 39.531  73.549  -13.296 1.00 27.59  ? 784  HIS   A CE1   1 
ATOM   4485  N  NE2   . HIS   C 3 491 ? 39.402  73.742  -11.940 1.00 24.18  ? 784  HIS   A NE2   1 
ATOM   4486  N  N     . ASP   C 3 492 ? 35.628  78.659  -13.797 1.00 30.74  ? 785  ASP   A N     1 
ATOM   4487  C  CA    . ASP   C 3 492 ? 34.674  79.697  -14.149 1.00 30.88  ? 785  ASP   A CA    1 
ATOM   4488  C  C     . ASP   C 3 492 ? 35.181  81.074  -13.717 1.00 30.76  ? 785  ASP   A C     1 
ATOM   4489  O  O     . ASP   C 3 492 ? 34.423  82.023  -13.729 1.00 29.26  ? 785  ASP   A O     1 
ATOM   4490  C  CB    . ASP   C 3 492 ? 33.313  79.370  -13.531 1.00 31.28  ? 785  ASP   A CB    1 
ATOM   4491  C  CG    . ASP   C 3 492 ? 33.190  79.484  -12.021 1.00 30.12  ? 785  ASP   A CG    1 
ATOM   4492  O  OD1   . ASP   C 3 492 ? 34.240  79.428  -11.301 1.00 30.47  ? 785  ASP   A OD1   1 
ATOM   4493  O  OD2   . ASP   C 3 492 ? 31.997  79.640  -11.563 1.00 28.12  ? 785  ASP   A OD2   1 
ATOM   4494  N  N     . GLU   C 3 493 ? 36.480  81.184  -13.403 1.00 33.30  ? 786  GLU   A N     1 
ATOM   4495  C  CA    . GLU   C 3 493 ? 37.067  82.396  -12.864 1.00 34.16  ? 786  GLU   A CA    1 
ATOM   4496  C  C     . GLU   C 3 493 ? 38.317  82.759  -13.665 1.00 30.92  ? 786  GLU   A C     1 
ATOM   4497  O  O     . GLU   C 3 493 ? 39.066  81.867  -14.052 1.00 27.67  ? 786  GLU   A O     1 
ATOM   4498  C  CB    . GLU   C 3 493 ? 37.365  82.150  -11.384 1.00 37.34  ? 786  GLU   A CB    1 
ATOM   4499  C  CG    . GLU   C 3 493 ? 38.172  83.248  -10.741 1.00 41.29  ? 786  GLU   A CG    1 
ATOM   4500  C  CD    . GLU   C 3 493 ? 38.452  83.102  -9.247  1.00 43.95  ? 786  GLU   A CD    1 
ATOM   4501  O  OE1   . GLU   C 3 493 ? 38.165  81.996  -8.649  1.00 42.81  ? 786  GLU   A OE1   1 
ATOM   4502  O  OE2   . GLU   C 3 493 ? 38.958  84.113  -8.681  1.00 38.71  ? 786  GLU   A OE2   1 
ATOM   4503  N  N     . LEU   C 3 494 ? 38.486  84.069  -13.922 1.00 29.14  ? 787  LEU   A N     1 
ATOM   4504  C  CA    . LEU   C 3 494 ? 39.673  84.665  -14.509 1.00 31.70  ? 787  LEU   A CA    1 
ATOM   4505  C  C     . LEU   C 3 494 ? 40.270  85.675  -13.524 1.00 31.90  ? 787  LEU   A C     1 
ATOM   4506  O  O     . LEU   C 3 494 ? 39.527  86.438  -12.898 1.00 33.99  ? 787  LEU   A O     1 
ATOM   4507  C  CB    . LEU   C 3 494 ? 39.296  85.368  -15.823 1.00 34.51  ? 787  LEU   A CB    1 
ATOM   4508  C  CG    . LEU   C 3 494 ? 39.154  84.473  -17.050 1.00 33.70  ? 787  LEU   A CG    1 
ATOM   4509  C  CD1   . LEU   C 3 494 ? 38.897  85.291  -18.295 1.00 35.43  ? 787  LEU   A CD1   1 
ATOM   4510  C  CD2   . LEU   C 3 494 ? 40.388  83.610  -17.242 1.00 35.64  ? 787  LEU   A CD2   1 
ATOM   4511  N  N     . VAL   C 3 495 ? 41.605  85.623  -13.353 1.00 30.62  ? 788  VAL   A N     1 
ATOM   4512  C  CA    . VAL   C 3 495 ? 42.353  86.615  -12.580 1.00 30.70  ? 788  VAL   A CA    1 
ATOM   4513  C  C     . VAL   C 3 495 ? 43.276  87.346  -13.549 1.00 31.92  ? 788  VAL   A C     1 
ATOM   4514  O  O     . VAL   C 3 495 ? 44.058  86.713  -14.280 1.00 30.27  ? 788  VAL   A O     1 
ATOM   4515  C  CB    . VAL   C 3 495 ? 43.149  86.007  -11.402 1.00 31.13  ? 788  VAL   A CB    1 
ATOM   4516  C  CG1   . VAL   C 3 495 ? 43.816  87.084  -10.561 1.00 31.98  ? 788  VAL   A CG1   1 
ATOM   4517  C  CG2   . VAL   C 3 495 ? 42.280  85.106  -10.526 1.00 30.87  ? 788  VAL   A CG2   1 
ATOM   4518  N  N     . LEU   C 3 496 ? 43.113  88.675  -13.586 1.00 31.33  ? 789  LEU   A N     1 
ATOM   4519  C  CA    . LEU   C 3 496 ? 43.913  89.536  -14.439 1.00 33.56  ? 789  LEU   A CA    1 
ATOM   4520  C  C     . LEU   C 3 496 ? 44.763  90.457  -13.577 1.00 32.83  ? 789  LEU   A C     1 
ATOM   4521  O  O     . LEU   C 3 496 ? 44.477  90.626  -12.397 1.00 36.48  ? 789  LEU   A O     1 
ATOM   4522  C  CB    . LEU   C 3 496 ? 42.984  90.370  -15.318 1.00 36.04  ? 789  LEU   A CB    1 
ATOM   4523  C  CG    . LEU   C 3 496 ? 41.827  89.618  -15.968 1.00 39.63  ? 789  LEU   A CG    1 
ATOM   4524  C  CD1   . LEU   C 3 496 ? 40.967  90.603  -16.743 1.00 39.90  ? 789  LEU   A CD1   1 
ATOM   4525  C  CD2   . LEU   C 3 496 ? 42.337  88.503  -16.874 1.00 38.60  ? 789  LEU   A CD2   1 
ATOM   4526  N  N     . GLU   C 3 497 ? 45.769  91.084  -14.197 1.00 34.31  ? 790  GLU   A N     1 
ATOM   4527  C  CA    . GLU   C 3 497 ? 46.575  92.101  -13.550 1.00 34.23  ? 790  GLU   A CA    1 
ATOM   4528  C  C     . GLU   C 3 497 ? 46.637  93.313  -14.471 1.00 36.27  ? 790  GLU   A C     1 
ATOM   4529  O  O     . GLU   C 3 497 ? 46.947  93.174  -15.651 1.00 37.82  ? 790  GLU   A O     1 
ATOM   4530  C  CB    . GLU   C 3 497 ? 47.988  91.572  -13.293 1.00 35.53  ? 790  GLU   A CB    1 
ATOM   4531  C  CG    . GLU   C 3 497 ? 48.729  92.207  -12.121 1.00 34.05  ? 790  GLU   A CG    1 
ATOM   4532  C  CD    . GLU   C 3 497 ? 50.139  91.651  -11.979 1.00 40.45  ? 790  GLU   A CD    1 
ATOM   4533  O  OE1   . GLU   C 3 497 ? 50.661  91.115  -12.996 1.00 40.70  ? 790  GLU   A OE1   1 
ATOM   4534  O  OE2   . GLU   C 3 497 ? 50.697  91.682  -10.855 1.00 37.86  ? 790  GLU   A OE2   1 
ATOM   4535  N  N     . ALA   C 3 498 ? 46.368  94.500  -13.915 1.00 37.59  ? 791  ALA   A N     1 
ATOM   4536  C  CA    . ALA   C 3 498 ? 46.350  95.723  -14.702 1.00 37.93  ? 791  ALA   A CA    1 
ATOM   4537  C  C     . ALA   C 3 498 ? 46.992  96.855  -13.907 1.00 37.27  ? 791  ALA   A C     1 
ATOM   4538  O  O     . ALA   C 3 498 ? 46.913  96.865  -12.676 1.00 35.09  ? 791  ALA   A O     1 
ATOM   4539  C  CB    . ALA   C 3 498 ? 44.932  96.074  -15.069 1.00 37.30  ? 791  ALA   A CB    1 
ATOM   4540  N  N     . PRO   C 3 499 ? 47.605  97.855  -14.581 1.00 40.49  ? 792  PRO   A N     1 
ATOM   4541  C  CA    . PRO   C 3 499 ? 48.051  99.078  -13.897 1.00 43.22  ? 792  PRO   A CA    1 
ATOM   4542  C  C     . PRO   C 3 499 ? 46.855  99.719  -13.189 1.00 44.85  ? 792  PRO   A C     1 
ATOM   4543  O  O     . PRO   C 3 499 ? 45.767  99.711  -13.750 1.00 42.05  ? 792  PRO   A O     1 
ATOM   4544  C  CB    . PRO   C 3 499 ? 48.617  99.943  -15.036 1.00 41.23  ? 792  PRO   A CB    1 
ATOM   4545  C  CG    . PRO   C 3 499 ? 48.968  98.945  -16.143 1.00 42.31  ? 792  PRO   A CG    1 
ATOM   4546  C  CD    . PRO   C 3 499 ? 47.907  97.865  -16.025 1.00 40.29  ? 792  PRO   A CD    1 
ATOM   4547  N  N     . LYS   C 3 500 ? 47.060  100.200 -11.944 1.00 46.90  ? 793  LYS   A N     1 
ATOM   4548  C  CA    . LYS   C 3 500 ? 46.020  100.777 -11.097 1.00 52.77  ? 793  LYS   A CA    1 
ATOM   4549  C  C     . LYS   C 3 500 ? 45.168  101.794 -11.868 1.00 56.93  ? 793  LYS   A C     1 
ATOM   4550  O  O     . LYS   C 3 500 ? 43.977  101.914 -11.592 1.00 66.72  ? 793  LYS   A O     1 
ATOM   4551  C  CB    . LYS   C 3 500 ? 46.636  101.429 -9.851  1.00 47.36  ? 793  LYS   A CB    1 
ATOM   4552  N  N     . GLU   C 3 501 ? 45.759  102.511 -12.831 1.00 58.75  ? 794  GLU   A N     1 
ATOM   4553  C  CA    . GLU   C 3 501 ? 45.027  103.509 -13.606 1.00 66.17  ? 794  GLU   A CA    1 
ATOM   4554  C  C     . GLU   C 3 501 ? 44.033  102.843 -14.553 1.00 66.54  ? 794  GLU   A C     1 
ATOM   4555  O  O     . GLU   C 3 501 ? 42.931  103.354 -14.728 1.00 62.40  ? 794  GLU   A O     1 
ATOM   4556  C  CB    . GLU   C 3 501 ? 45.930  104.373 -14.494 1.00 74.29  ? 794  GLU   A CB    1 
ATOM   4557  C  CG    . GLU   C 3 501 ? 47.291  104.685 -13.896 1.00 79.27  ? 794  GLU   A CG    1 
ATOM   4558  C  CD    . GLU   C 3 501 ? 48.339  103.599 -14.093 1.00 77.99  ? 794  GLU   A CD    1 
ATOM   4559  O  OE1   . GLU   C 3 501 ? 48.543  103.165 -15.260 1.00 67.41  ? 794  GLU   A OE1   1 
ATOM   4560  O  OE2   . GLU   C 3 501 ? 48.951  103.186 -13.080 1.00 76.84  ? 794  GLU   A OE2   1 
ATOM   4561  N  N     . ARG   C 3 502 ? 44.436  101.711 -15.156 1.00 60.08  ? 795  ARG   A N     1 
ATOM   4562  C  CA    . ARG   C 3 502 ? 43.662  101.048 -16.194 1.00 56.58  ? 795  ARG   A CA    1 
ATOM   4563  C  C     . ARG   C 3 502 ? 42.732  99.975  -15.628 1.00 51.48  ? 795  ARG   A C     1 
ATOM   4564  O  O     . ARG   C 3 502 ? 42.011  99.350  -16.395 1.00 56.73  ? 795  ARG   A O     1 
ATOM   4565  C  CB    . ARG   C 3 502 ? 44.590  100.391 -17.228 1.00 63.05  ? 795  ARG   A CB    1 
ATOM   4566  C  CG    . ARG   C 3 502 ? 45.590  101.323 -17.905 1.00 68.42  ? 795  ARG   A CG    1 
ATOM   4567  C  CD    . ARG   C 3 502 ? 44.965  102.437 -18.729 1.00 77.01  ? 795  ARG   A CD    1 
ATOM   4568  N  NE    . ARG   C 3 502 ? 44.132  101.956 -19.829 1.00 83.54  ? 795  ARG   A NE    1 
ATOM   4569  C  CZ    . ARG   C 3 502 ? 44.549  101.806 -21.084 1.00 86.02  ? 795  ARG   A CZ    1 
ATOM   4570  N  NH1   . ARG   C 3 502 ? 43.670  101.642 -22.058 1.00 80.95  ? 795  ARG   A NH1   1 
ATOM   4571  N  NH2   . ARG   C 3 502 ? 45.841  101.844 -21.371 1.00 82.07  ? 795  ARG   A NH2   1 
ATOM   4572  N  N     . ALA   C 3 503 ? 42.708  99.775  -14.307 1.00 48.78  ? 796  ALA   A N     1 
ATOM   4573  C  CA    . ALA   C 3 503 ? 42.080  98.598  -13.720 1.00 49.17  ? 796  ALA   A CA    1 
ATOM   4574  C  C     . ALA   C 3 503 ? 40.554  98.633  -13.851 1.00 50.65  ? 796  ALA   A C     1 
ATOM   4575  O  O     . ALA   C 3 503 ? 39.926  97.580  -13.971 1.00 49.41  ? 796  ALA   A O     1 
ATOM   4576  C  CB    . ALA   C 3 503 ? 42.507  98.438  -12.278 1.00 44.51  ? 796  ALA   A CB    1 
ATOM   4577  N  N     . GLU   C 3 504 ? 39.959  99.833  -13.806 1.00 58.48  ? 797  GLU   A N     1 
ATOM   4578  C  CA    . GLU   C 3 504 ? 38.509  99.990  -13.905 1.00 57.17  ? 797  GLU   A CA    1 
ATOM   4579  C  C     . GLU   C 3 504 ? 38.038  99.623  -15.307 1.00 47.50  ? 797  GLU   A C     1 
ATOM   4580  O  O     . GLU   C 3 504 ? 37.024  98.949  -15.459 1.00 46.43  ? 797  GLU   A O     1 
ATOM   4581  C  CB    . GLU   C 3 504 ? 38.072  101.432 -13.617 1.00 64.00  ? 797  GLU   A CB    1 
ATOM   4582  C  CG    . GLU   C 3 504 ? 38.239  101.859 -12.168 1.00 70.82  ? 797  GLU   A CG    1 
ATOM   4583  C  CD    . GLU   C 3 504 ? 37.300  101.182 -11.185 1.00 73.22  ? 797  GLU   A CD    1 
ATOM   4584  O  OE1   . GLU   C 3 504 ? 36.333  100.521 -11.631 1.00 76.70  ? 797  GLU   A OE1   1 
ATOM   4585  O  OE2   . GLU   C 3 504 ? 37.547  101.306 -9.971  1.00 78.57  ? 797  GLU   A OE2   1 
ATOM   4586  N  N     . ALA   C 3 505 ? 38.793  100.101 -16.302 1.00 44.78  ? 798  ALA   A N     1 
ATOM   4587  C  CA    . ALA   C 3 505 ? 38.506  99.897  -17.712 1.00 50.04  ? 798  ALA   A CA    1 
ATOM   4588  C  C     . ALA   C 3 505 ? 38.733  98.442  -18.122 1.00 49.54  ? 798  ALA   A C     1 
ATOM   4589  O  O     . ALA   C 3 505 ? 38.012  97.933  -18.985 1.00 45.86  ? 798  ALA   A O     1 
ATOM   4590  C  CB    . ALA   C 3 505 ? 39.371  100.822 -18.539 1.00 49.62  ? 798  ALA   A CB    1 
ATOM   4591  N  N     . VAL   C 3 506 ? 39.760  97.808  -17.525 1.00 47.05  ? 799  VAL   A N     1 
ATOM   4592  C  CA    . VAL   C 3 506 ? 40.085  96.414  -17.786 1.00 44.59  ? 799  VAL   A CA    1 
ATOM   4593  C  C     . VAL   C 3 506 ? 38.961  95.564  -17.214 1.00 43.74  ? 799  VAL   A C     1 
ATOM   4594  O  O     . VAL   C 3 506 ? 38.512  94.625  -17.865 1.00 45.29  ? 799  VAL   A O     1 
ATOM   4595  C  CB    . VAL   C 3 506 ? 41.464  96.013  -17.221 1.00 43.07  ? 799  VAL   A CB    1 
ATOM   4596  C  CG1   . VAL   C 3 506 ? 41.656  94.506  -17.169 1.00 44.23  ? 799  VAL   A CG1   1 
ATOM   4597  C  CG2   . VAL   C 3 506 ? 42.607  96.644  -18.002 1.00 41.65  ? 799  VAL   A CG2   1 
ATOM   4598  N  N     . ALA   C 3 507 ? 38.468  95.933  -16.028 1.00 43.28  ? 800  ALA   A N     1 
ATOM   4599  C  CA    . ALA   C 3 507 ? 37.377  95.180  -15.421 1.00 47.73  ? 800  ALA   A CA    1 
ATOM   4600  C  C     . ALA   C 3 507 ? 36.137  95.238  -16.313 1.00 50.50  ? 800  ALA   A C     1 
ATOM   4601  O  O     . ALA   C 3 507 ? 35.489  94.221  -16.516 1.00 47.41  ? 800  ALA   A O     1 
ATOM   4602  C  CB    . ALA   C 3 507 ? 37.072  95.678  -14.030 1.00 44.55  ? 800  ALA   A CB    1 
ATOM   4603  N  N     . ARG   C 3 508 ? 35.814  96.434  -16.827 1.00 52.61  ? 801  ARG   A N     1 
ATOM   4604  C  CA    . ARG   C 3 508 ? 34.604  96.658  -17.605 1.00 56.11  ? 801  ARG   A CA    1 
ATOM   4605  C  C     . ARG   C 3 508 ? 34.660  95.875  -18.927 1.00 49.73  ? 801  ARG   A C     1 
ATOM   4606  O  O     . ARG   C 3 508 ? 33.700  95.212  -19.307 1.00 45.12  ? 801  ARG   A O     1 
ATOM   4607  C  CB    . ARG   C 3 508 ? 34.411  98.171  -17.783 1.00 64.77  ? 801  ARG   A CB    1 
ATOM   4608  C  CG    . ARG   C 3 508 ? 33.364  98.599  -18.809 1.00 75.16  ? 801  ARG   A CG    1 
ATOM   4609  C  CD    . ARG   C 3 508 ? 32.875  100.025 -18.568 1.00 87.03  ? 801  ARG   A CD    1 
ATOM   4610  N  NE    . ARG   C 3 508 ? 33.927  100.953 -18.137 1.00 89.08  ? 801  ARG   A NE    1 
ATOM   4611  C  CZ    . ARG   C 3 508 ? 34.022  101.505 -16.924 1.00 86.46  ? 801  ARG   A CZ    1 
ATOM   4612  N  NH1   . ARG   C 3 508 ? 33.004  101.445 -16.079 1.00 89.44  ? 801  ARG   A NH1   1 
ATOM   4613  N  NH2   . ARG   C 3 508 ? 35.139  102.119 -16.564 1.00 76.46  ? 801  ARG   A NH2   1 
ATOM   4614  N  N     . LEU   C 3 509 ? 35.789  95.939  -19.631 1.00 46.09  ? 802  LEU   A N     1 
ATOM   4615  C  CA    . LEU   C 3 509 ? 35.972  95.186  -20.861 1.00 46.24  ? 802  LEU   A CA    1 
ATOM   4616  C  C     . LEU   C 3 509 ? 35.882  93.677  -20.625 1.00 47.33  ? 802  LEU   A C     1 
ATOM   4617  O  O     . LEU   C 3 509 ? 35.259  92.978  -21.417 1.00 52.06  ? 802  LEU   A O     1 
ATOM   4618  C  CB    . LEU   C 3 509 ? 37.333  95.541  -21.448 1.00 50.21  ? 802  LEU   A CB    1 
ATOM   4619  C  CG    . LEU   C 3 509 ? 37.655  94.807  -22.744 1.00 57.33  ? 802  LEU   A CG    1 
ATOM   4620  C  CD1   . LEU   C 3 509 ? 36.866  95.393  -23.910 1.00 59.42  ? 802  LEU   A CD1   1 
ATOM   4621  C  CD2   . LEU   C 3 509 ? 39.143  94.852  -23.011 1.00 58.99  ? 802  LEU   A CD2   1 
ATOM   4622  N  N     . ALA   C 3 510 ? 36.526  93.173  -19.562 1.00 42.35  ? 803  ALA   A N     1 
ATOM   4623  C  CA    . ALA   C 3 510 ? 36.541  91.745  -19.287 1.00 40.95  ? 803  ALA   A CA    1 
ATOM   4624  C  C     . ALA   C 3 510 ? 35.128  91.239  -18.990 1.00 40.37  ? 803  ALA   A C     1 
ATOM   4625  O  O     . ALA   C 3 510 ? 34.734  90.188  -19.480 1.00 43.33  ? 803  ALA   A O     1 
ATOM   4626  C  CB    . ALA   C 3 510 ? 37.491  91.438  -18.151 1.00 41.31  ? 803  ALA   A CB    1 
ATOM   4627  N  N     . LYS   C 3 511 ? 34.382  91.984  -18.175 1.00 41.92  ? 804  LYS   A N     1 
ATOM   4628  C  CA    . LYS   C 3 511 ? 32.971  91.730  -17.895 1.00 44.31  ? 804  LYS   A CA    1 
ATOM   4629  C  C     . LYS   C 3 511 ? 32.142  91.650  -19.184 1.00 42.71  ? 804  LYS   A C     1 
ATOM   4630  O  O     . LYS   C 3 511 ? 31.412  90.691  -19.381 1.00 41.61  ? 804  LYS   A O     1 
ATOM   4631  C  CB    . LYS   C 3 511 ? 32.404  92.835  -16.992 1.00 43.28  ? 804  LYS   A CB    1 
ATOM   4632  C  CG    . LYS   C 3 511 ? 31.084  92.517  -16.294 1.00 46.97  ? 804  LYS   A CG    1 
ATOM   4633  C  CD    . LYS   C 3 511 ? 30.364  93.757  -15.761 1.00 50.47  ? 804  LYS   A CD    1 
ATOM   4634  C  CE    . LYS   C 3 511 ? 29.470  93.495  -14.566 1.00 53.44  ? 804  LYS   A CE    1 
ATOM   4635  N  NZ    . LYS   C 3 511 ? 28.287  92.670  -14.898 1.00 53.38  ? 804  LYS   A NZ    1 
ATOM   4636  N  N     . GLU   C 3 512 ? 32.217  92.668  -20.047 1.00 44.21  ? 805  GLU   A N     1 
ATOM   4637  C  CA    . GLU   C 3 512 ? 31.487  92.668  -21.309 1.00 49.90  ? 805  GLU   A CA    1 
ATOM   4638  C  C     . GLU   C 3 512 ? 31.787  91.395  -22.110 1.00 47.06  ? 805  GLU   A C     1 
ATOM   4639  O  O     . GLU   C 3 512 ? 30.866  90.696  -22.533 1.00 48.10  ? 805  GLU   A O     1 
ATOM   4640  C  CB    . GLU   C 3 512 ? 31.833  93.897  -22.156 1.00 52.10  ? 805  GLU   A CB    1 
ATOM   4641  C  CG    . GLU   C 3 512 ? 31.272  95.193  -21.607 1.00 63.76  ? 805  GLU   A CG    1 
ATOM   4642  C  CD    . GLU   C 3 512 ? 31.596  96.449  -22.405 1.00 77.04  ? 805  GLU   A CD    1 
ATOM   4643  O  OE1   . GLU   C 3 512 ? 30.653  97.227  -22.683 1.00 87.28  ? 805  GLU   A OE1   1 
ATOM   4644  O  OE2   . GLU   C 3 512 ? 32.787  96.657  -22.740 1.00 82.93  ? 805  GLU   A OE2   1 
ATOM   4645  N  N     . VAL   C 3 513 ? 33.077  91.113  -22.334 1.00 41.57  ? 806  VAL   A N     1 
ATOM   4646  C  CA    . VAL   C 3 513 ? 33.499  90.005  -23.181 1.00 41.21  ? 806  VAL   A CA    1 
ATOM   4647  C  C     . VAL   C 3 513 ? 32.995  88.685  -22.603 1.00 40.05  ? 806  VAL   A C     1 
ATOM   4648  O  O     . VAL   C 3 513 ? 32.501  87.831  -23.325 1.00 43.95  ? 806  VAL   A O     1 
ATOM   4649  C  CB    . VAL   C 3 513 ? 35.031  89.999  -23.356 1.00 38.59  ? 806  VAL   A CB    1 
ATOM   4650  C  CG1   . VAL   C 3 513 ? 35.530  88.721  -24.005 1.00 37.78  ? 806  VAL   A CG1   1 
ATOM   4651  C  CG2   . VAL   C 3 513 ? 35.501  91.208  -24.148 1.00 38.12  ? 806  VAL   A CG2   1 
ATOM   4652  N  N     . MET   C 3 514 ? 33.099  88.524  -21.284 1.00 40.24  ? 807  MET   A N     1 
ATOM   4653  C  CA    . MET   C 3 514 ? 32.804  87.245  -20.664 1.00 38.86  ? 807  MET   A CA    1 
ATOM   4654  C  C     . MET   C 3 514 ? 31.304  86.947  -20.678 1.00 40.83  ? 807  MET   A C     1 
ATOM   4655  O  O     . MET   C 3 514 ? 30.912  85.781  -20.643 1.00 39.93  ? 807  MET   A O     1 
ATOM   4656  C  CB    . MET   C 3 514 ? 33.324  87.222  -19.227 1.00 36.68  ? 807  MET   A CB    1 
ATOM   4657  C  CG    . MET   C 3 514 ? 34.809  86.932  -19.146 1.00 39.46  ? 807  MET   A CG    1 
ATOM   4658  S  SD    . MET   C 3 514 ? 35.431  87.091  -17.470 1.00 36.10  ? 807  MET   A SD    1 
ATOM   4659  C  CE    . MET   C 3 514 ? 34.789  85.597  -16.720 1.00 35.27  ? 807  MET   A CE    1 
ATOM   4660  N  N     . GLU   C 3 515 ? 30.475  87.997  -20.711 1.00 42.24  ? 808  GLU   A N     1 
ATOM   4661  C  CA    . GLU   C 3 515 ? 29.023  87.859  -20.613 1.00 45.52  ? 808  GLU   A CA    1 
ATOM   4662  C  C     . GLU   C 3 515 ? 28.371  87.814  -22.000 1.00 42.48  ? 808  GLU   A C     1 
ATOM   4663  O  O     . GLU   C 3 515 ? 27.205  87.455  -22.123 1.00 42.85  ? 808  GLU   A O     1 
ATOM   4664  C  CB    . GLU   C 3 515 ? 28.420  89.037  -19.842 1.00 46.40  ? 808  GLU   A CB    1 
ATOM   4665  C  CG    . GLU   C 3 515 ? 28.844  89.114  -18.389 1.00 46.55  ? 808  GLU   A CG    1 
ATOM   4666  C  CD    . GLU   C 3 515 ? 28.156  90.192  -17.574 1.00 44.91  ? 808  GLU   A CD    1 
ATOM   4667  O  OE1   . GLU   C 3 515 ? 27.804  91.244  -18.160 1.00 46.38  ? 808  GLU   A OE1   1 
ATOM   4668  O  OE2   . GLU   C 3 515 ? 28.013  89.993  -16.354 1.00 42.59  ? 808  GLU   A OE2   1 
ATOM   4669  N  N     . GLY   C 3 516 ? 29.110  88.204  -23.040 1.00 43.51  ? 809  GLY   A N     1 
ATOM   4670  C  CA    . GLY   C 3 516 ? 28.563  88.265  -24.385 1.00 45.84  ? 809  GLY   A CA    1 
ATOM   4671  C  C     . GLY   C 3 516 ? 29.092  87.174  -25.316 1.00 42.45  ? 809  GLY   A C     1 
ATOM   4672  O  O     . GLY   C 3 516 ? 29.061  87.371  -26.531 1.00 43.94  ? 809  GLY   A O     1 
ATOM   4673  N  N     . VAL   C 3 517 ? 29.522  86.024  -24.763 1.00 39.71  ? 810  VAL   A N     1 
ATOM   4674  C  CA    . VAL   C 3 517 ? 30.275  85.041  -25.540 1.00 40.44  ? 810  VAL   A CA    1 
ATOM   4675  C  C     . VAL   C 3 517 ? 29.334  84.233  -26.429 1.00 36.48  ? 810  VAL   A C     1 
ATOM   4676  O  O     . VAL   C 3 517 ? 29.775  83.793  -27.474 1.00 40.80  ? 810  VAL   A O     1 
ATOM   4677  C  CB    . VAL   C 3 517 ? 31.188  84.080  -24.724 1.00 40.25  ? 810  VAL   A CB    1 
ATOM   4678  C  CG1   . VAL   C 3 517 ? 32.524  84.705  -24.369 1.00 42.84  ? 810  VAL   A CG1   1 
ATOM   4679  C  CG2   . VAL   C 3 517 ? 30.533  83.490  -23.494 1.00 41.07  ? 810  VAL   A CG2   1 
ATOM   4680  N  N     . TYR   C 3 518 ? 28.080  84.005  -26.012 1.00 37.88  ? 811  TYR   A N     1 
ATOM   4681  C  CA    . TYR   C 3 518 ? 27.187  83.120  -26.747 1.00 36.16  ? 811  TYR   A CA    1 
ATOM   4682  C  C     . TYR   C 3 518 ? 25.730  83.439  -26.445 1.00 36.98  ? 811  TYR   A C     1 
ATOM   4683  O  O     . TYR   C 3 518 ? 25.381  83.828  -25.328 1.00 34.27  ? 811  TYR   A O     1 
ATOM   4684  C  CB    . TYR   C 3 518 ? 27.472  81.659  -26.400 1.00 41.48  ? 811  TYR   A CB    1 
ATOM   4685  C  CG    . TYR   C 3 518 ? 26.860  80.637  -27.328 1.00 46.72  ? 811  TYR   A CG    1 
ATOM   4686  C  CD1   . TYR   C 3 518 ? 25.556  80.181  -27.156 1.00 47.30  ? 811  TYR   A CD1   1 
ATOM   4687  C  CD2   . TYR   C 3 518 ? 27.585  80.134  -28.396 1.00 45.52  ? 811  TYR   A CD2   1 
ATOM   4688  C  CE1   . TYR   C 3 518 ? 25.001  79.236  -28.011 1.00 45.79  ? 811  TYR   A CE1   1 
ATOM   4689  C  CE2   . TYR   C 3 518 ? 27.053  79.180  -29.248 1.00 47.88  ? 811  TYR   A CE2   1 
ATOM   4690  C  CZ    . TYR   C 3 518 ? 25.758  78.731  -29.054 1.00 47.77  ? 811  TYR   A CZ    1 
ATOM   4691  O  OH    . TYR   C 3 518 ? 25.274  77.795  -29.925 1.00 54.77  ? 811  TYR   A OH    1 
ATOM   4692  N  N     . PRO   C 3 519 ? 24.838  83.314  -27.454 1.00 36.07  ? 812  PRO   A N     1 
ATOM   4693  C  CA    . PRO   C 3 519 ? 23.406  83.533  -27.254 1.00 38.43  ? 812  PRO   A CA    1 
ATOM   4694  C  C     . PRO   C 3 519 ? 22.688  82.416  -26.489 1.00 41.57  ? 812  PRO   A C     1 
ATOM   4695  O  O     . PRO   C 3 519 ? 21.973  81.575  -27.063 1.00 42.96  ? 812  PRO   A O     1 
ATOM   4696  C  CB    . PRO   C 3 519 ? 22.863  83.666  -28.686 1.00 37.15  ? 812  PRO   A CB    1 
ATOM   4697  C  CG    . PRO   C 3 519 ? 23.834  82.863  -29.526 1.00 39.27  ? 812  PRO   A CG    1 
ATOM   4698  C  CD    . PRO   C 3 519 ? 25.182  83.066  -28.861 1.00 36.58  ? 812  PRO   A CD    1 
ATOM   4699  N  N     . LEU   C 3 520 ? 22.826  82.468  -25.162 1.00 36.57  ? 813  LEU   A N     1 
ATOM   4700  C  CA    . LEU   C 3 520 ? 22.186  81.486  -24.306 1.00 39.14  ? 813  LEU   A CA    1 
ATOM   4701  C  C     . LEU   C 3 520 ? 20.766  81.929  -23.977 1.00 40.83  ? 813  LEU   A C     1 
ATOM   4702  O  O     . LEU   C 3 520 ? 20.431  83.098  -24.112 1.00 44.87  ? 813  LEU   A O     1 
ATOM   4703  C  CB    . LEU   C 3 520 ? 23.009  81.346  -23.027 1.00 38.57  ? 813  LEU   A CB    1 
ATOM   4704  C  CG    . LEU   C 3 520 ? 24.433  80.833  -23.215 1.00 37.48  ? 813  LEU   A CG    1 
ATOM   4705  C  CD1   . LEU   C 3 520 ? 25.148  80.769  -21.873 1.00 38.01  ? 813  LEU   A CD1   1 
ATOM   4706  C  CD2   . LEU   C 3 520 ? 24.443  79.465  -23.886 1.00 38.70  ? 813  LEU   A CD2   1 
ATOM   4707  N  N     . ALA   C 3 521 ? 19.967  80.972  -23.501 1.00 42.46  ? 814  ALA   A N     1 
ATOM   4708  C  CA    . ALA   C 3 521 ? 18.594  81.221  -23.092 1.00 41.59  ? 814  ALA   A CA    1 
ATOM   4709  C  C     . ALA   C 3 521 ? 18.585  81.837  -21.695 1.00 41.64  ? 814  ALA   A C     1 
ATOM   4710  O  O     . ALA   C 3 521 ? 17.530  82.273  -21.231 1.00 39.43  ? 814  ALA   A O     1 
ATOM   4711  C  CB    . ALA   C 3 521 ? 17.808  79.937  -23.138 1.00 39.37  ? 814  ALA   A CB    1 
ATOM   4712  N  N     . VAL   C 3 522 ? 19.764  81.845  -21.042 1.00 40.68  ? 815  VAL   A N     1 
ATOM   4713  C  CA    . VAL   C 3 522 ? 19.970  82.484  -19.748 1.00 41.18  ? 815  VAL   A CA    1 
ATOM   4714  C  C     . VAL   C 3 522 ? 21.107  83.496  -19.878 1.00 38.29  ? 815  VAL   A C     1 
ATOM   4715  O  O     . VAL   C 3 522 ? 22.112  83.223  -20.499 1.00 40.21  ? 815  VAL   A O     1 
ATOM   4716  C  CB    . VAL   C 3 522 ? 20.262  81.448  -18.641 1.00 45.62  ? 815  VAL   A CB    1 
ATOM   4717  C  CG1   . VAL   C 3 522 ? 20.673  82.087  -17.327 1.00 49.64  ? 815  VAL   A CG1   1 
ATOM   4718  C  CG2   . VAL   C 3 522 ? 19.066  80.556  -18.374 1.00 49.78  ? 815  VAL   A CG2   1 
ATOM   4719  N  N     . PRO   C 3 523 ? 21.016  84.705  -19.297 1.00 43.29  ? 816  PRO   A N     1 
ATOM   4720  C  CA    . PRO   C 3 523 ? 22.136  85.645  -19.368 1.00 44.63  ? 816  PRO   A CA    1 
ATOM   4721  C  C     . PRO   C 3 523 ? 23.281  85.114  -18.505 1.00 41.22  ? 816  PRO   A C     1 
ATOM   4722  O  O     . PRO   C 3 523 ? 23.045  84.539  -17.450 1.00 39.70  ? 816  PRO   A O     1 
ATOM   4723  C  CB    . PRO   C 3 523 ? 21.535  86.941  -18.796 1.00 46.03  ? 816  PRO   A CB    1 
ATOM   4724  C  CG    . PRO   C 3 523 ? 20.496  86.438  -17.799 1.00 45.91  ? 816  PRO   A CG    1 
ATOM   4725  C  CD    . PRO   C 3 523 ? 19.906  85.197  -18.450 1.00 47.30  ? 816  PRO   A CD    1 
ATOM   4726  N  N     . LEU   C 3 524 ? 24.507  85.250  -19.005 1.00 40.94  ? 817  LEU   A N     1 
ATOM   4727  C  CA    . LEU   C 3 524 ? 25.710  85.041  -18.226 1.00 45.05  ? 817  LEU   A CA    1 
ATOM   4728  C  C     . LEU   C 3 524 ? 26.036  86.314  -17.443 1.00 48.50  ? 817  LEU   A C     1 
ATOM   4729  O  O     . LEU   C 3 524 ? 26.148  87.390  -18.028 1.00 54.42  ? 817  LEU   A O     1 
ATOM   4730  C  CB    . LEU   C 3 524 ? 26.857  84.743  -19.188 1.00 46.20  ? 817  LEU   A CB    1 
ATOM   4731  C  CG    . LEU   C 3 524 ? 26.817  83.386  -19.867 1.00 46.94  ? 817  LEU   A CG    1 
ATOM   4732  C  CD1   . LEU   C 3 524 ? 27.983  83.255  -20.821 1.00 47.19  ? 817  LEU   A CD1   1 
ATOM   4733  C  CD2   . LEU   C 3 524 ? 26.820  82.261  -18.843 1.00 48.66  ? 817  LEU   A CD2   1 
ATOM   4734  N  N     A GLU   C 3 525 ? 26.230  86.163  -16.130 0.50 47.32  ? 818  GLU   A N     1 
ATOM   4735  N  N     B GLU   C 3 525 ? 26.220  86.167  -16.128 0.50 49.84  ? 818  GLU   A N     1 
ATOM   4736  C  CA    A GLU   C 3 525 ? 26.566  87.264  -15.243 0.50 45.21  ? 818  GLU   A CA    1 
ATOM   4737  C  CA    B GLU   C 3 525 ? 26.558  87.285  -15.265 0.50 49.16  ? 818  GLU   A CA    1 
ATOM   4738  C  C     A GLU   C 3 525 ? 27.934  86.980  -14.615 0.50 44.98  ? 818  GLU   A C     1 
ATOM   4739  C  C     B GLU   C 3 525 ? 27.919  86.989  -14.611 0.50 47.31  ? 818  GLU   A C     1 
ATOM   4740  O  O     A GLU   C 3 525 ? 28.225  85.859  -14.188 0.50 39.84  ? 818  GLU   A O     1 
ATOM   4741  O  O     B GLU   C 3 525 ? 28.207  85.866  -14.188 0.50 41.85  ? 818  GLU   A O     1 
ATOM   4742  C  CB    A GLU   C 3 525 ? 25.440  87.411  -14.215 0.50 45.77  ? 818  GLU   A CB    1 
ATOM   4743  C  CB    B GLU   C 3 525 ? 25.388  87.545  -14.304 0.50 52.92  ? 818  GLU   A CB    1 
ATOM   4744  C  CG    A GLU   C 3 525 ? 25.600  88.522  -13.182 0.50 43.66  ? 818  GLU   A CG    1 
ATOM   4745  C  CG    B GLU   C 3 525 ? 24.010  87.605  -14.983 0.50 54.92  ? 818  GLU   A CG    1 
ATOM   4746  C  CD    A GLU   C 3 525 ? 24.533  88.492  -12.099 0.50 41.67  ? 818  GLU   A CD    1 
ATOM   4747  C  CD    B GLU   C 3 525 ? 23.498  88.910  -15.587 0.50 50.91  ? 818  GLU   A CD    1 
ATOM   4748  O  OE1   A GLU   C 3 525 ? 23.350  88.584  -12.439 0.50 42.15  ? 818  GLU   A OE1   1 
ATOM   4749  O  OE1   B GLU   C 3 525 ? 22.521  89.435  -15.045 0.50 49.50  ? 818  GLU   A OE1   1 
ATOM   4750  O  OE2   A GLU   C 3 525 ? 24.887  88.351  -10.924 0.50 42.24  ? 818  GLU   A OE2   1 
ATOM   4751  O  OE2   B GLU   C 3 525 ? 24.006  89.352  -16.642 0.50 46.40  ? 818  GLU   A OE2   1 
ATOM   4752  N  N     . VAL   C 3 526 ? 28.769  88.023  -14.569 1.00 46.37  ? 819  VAL   A N     1 
ATOM   4753  C  CA    . VAL   C 3 526 ? 30.112  87.952  -14.017 1.00 50.69  ? 819  VAL   A CA    1 
ATOM   4754  C  C     . VAL   C 3 526 ? 30.213  88.856  -12.778 1.00 49.06  ? 819  VAL   A C     1 
ATOM   4755  O  O     . VAL   C 3 526 ? 29.912  90.045  -12.833 1.00 41.29  ? 819  VAL   A O     1 
ATOM   4756  C  CB    . VAL   C 3 526 ? 31.096  88.327  -15.145 1.00 50.52  ? 819  VAL   A CB    1 
ATOM   4757  C  CG1   . VAL   C 3 526 ? 32.378  88.978  -14.658 1.00 51.58  ? 819  VAL   A CG1   1 
ATOM   4758  C  CG2   . VAL   C 3 526 ? 31.394  87.109  -16.005 1.00 53.19  ? 819  VAL   A CG2   1 
ATOM   4759  N  N     . GLU   C 3 527 ? 30.620  88.256  -11.649 1.00 50.13  ? 820  GLU   A N     1 
ATOM   4760  C  CA    . GLU   C 3 527 ? 30.999  88.972  -10.441 1.00 53.90  ? 820  GLU   A CA    1 
ATOM   4761  C  C     . GLU   C 3 527 ? 32.439  89.487  -10.595 1.00 53.36  ? 820  GLU   A C     1 
ATOM   4762  O  O     . GLU   C 3 527 ? 33.374  88.688  -10.610 1.00 51.01  ? 820  GLU   A O     1 
ATOM   4763  C  CB    . GLU   C 3 527 ? 30.874  88.001  -9.263  1.00 57.62  ? 820  GLU   A CB    1 
ATOM   4764  C  CG    . GLU   C 3 527 ? 30.636  88.653  -7.920  1.00 67.00  ? 820  GLU   A CG    1 
ATOM   4765  C  CD    . GLU   C 3 527 ? 29.183  88.773  -7.486  1.00 75.59  ? 820  GLU   A CD    1 
ATOM   4766  O  OE1   . GLU   C 3 527 ? 28.962  89.124  -6.308  1.00 86.04  ? 820  GLU   A OE1   1 
ATOM   4767  O  OE2   . GLU   C 3 527 ? 28.271  88.508  -8.304  1.00 72.74  ? 820  GLU   A OE2   1 
ATOM   4768  N  N     . VAL   C 3 528 ? 32.611  90.815  -10.691 1.00 50.22  ? 821  VAL   A N     1 
ATOM   4769  C  CA    . VAL   C 3 528 ? 33.914  91.471  -10.787 1.00 48.40  ? 821  VAL   A CA    1 
ATOM   4770  C  C     . VAL   C 3 528 ? 34.352  92.038  -9.430  1.00 49.00  ? 821  VAL   A C     1 
ATOM   4771  O  O     . VAL   C 3 528 ? 33.531  92.568  -8.679  1.00 51.15  ? 821  VAL   A O     1 
ATOM   4772  C  CB    . VAL   C 3 528 ? 33.886  92.629  -11.802 1.00 48.55  ? 821  VAL   A CB    1 
ATOM   4773  C  CG1   . VAL   C 3 528 ? 35.275  92.912  -12.350 1.00 49.65  ? 821  VAL   A CG1   1 
ATOM   4774  C  CG2   . VAL   C 3 528 ? 32.906  92.381  -12.934 1.00 52.24  ? 821  VAL   A CG2   1 
ATOM   4775  N  N     . GLY   C 3 529 ? 35.667  91.979  -9.158  1.00 48.96  ? 822  GLY   A N     1 
ATOM   4776  C  CA    . GLY   C 3 529 ? 36.301  92.669  -8.036  1.00 43.56  ? 822  GLY   A CA    1 
ATOM   4777  C  C     . GLY   C 3 529 ? 37.716  93.153  -8.376  1.00 44.64  ? 822  GLY   A C     1 
ATOM   4778  O  O     . GLY   C 3 529 ? 38.425  92.546  -9.175  1.00 43.92  ? 822  GLY   A O     1 
ATOM   4779  N  N     . ILE   C 3 530 ? 38.119  94.287  -7.789  1.00 44.65  ? 823  ILE   A N     1 
ATOM   4780  C  CA    . ILE   C 3 530 ? 39.463  94.825  -7.953  1.00 47.48  ? 823  ILE   A CA    1 
ATOM   4781  C  C     . ILE   C 3 530 ? 40.104  94.920  -6.568  1.00 47.17  ? 823  ILE   A C     1 
ATOM   4782  O  O     . ILE   C 3 530 ? 39.431  95.258  -5.600  1.00 45.12  ? 823  ILE   A O     1 
ATOM   4783  C  CB    . ILE   C 3 530 ? 39.434  96.193  -8.671  1.00 45.78  ? 823  ILE   A CB    1 
ATOM   4784  C  CG1   . ILE   C 3 530 ? 38.608  96.135  -9.958  1.00 44.66  ? 823  ILE   A CG1   1 
ATOM   4785  C  CG2   . ILE   C 3 530 ? 40.846  96.700  -8.933  1.00 46.27  ? 823  ILE   A CG2   1 
ATOM   4786  C  CD1   . ILE   C 3 530 ? 38.555  97.432  -10.725 1.00 43.70  ? 823  ILE   A CD1   1 
ATOM   4787  N  N     . GLY   C 3 531 ? 41.403  94.620  -6.478  1.00 45.86  ? 824  GLY   A N     1 
ATOM   4788  C  CA    . GLY   C 3 531 ? 42.083  94.619  -5.195  1.00 44.24  ? 824  GLY   A CA    1 
ATOM   4789  C  C     . GLY   C 3 531 ? 43.591  94.428  -5.344  1.00 47.35  ? 824  GLY   A C     1 
ATOM   4790  O  O     . GLY   C 3 531 ? 44.078  94.049  -6.408  1.00 43.40  ? 824  GLY   A O     1 
ATOM   4791  N  N     . GLU   C 3 532 ? 44.318  94.683  -4.247  1.00 48.98  ? 825  GLU   A N     1 
ATOM   4792  C  CA    . GLU   C 3 532 ? 45.769  94.565  -4.227  1.00 50.73  ? 825  GLU   A CA    1 
ATOM   4793  C  C     . GLU   C 3 532 ? 46.163  93.096  -4.074  1.00 46.85  ? 825  GLU   A C     1 
ATOM   4794  O  O     . GLU   C 3 532 ? 47.275  92.708  -4.411  1.00 44.82  ? 825  GLU   A O     1 
ATOM   4795  C  CB    . GLU   C 3 532 ? 46.354  95.413  -3.093  1.00 54.82  ? 825  GLU   A CB    1 
ATOM   4796  C  CG    . GLU   C 3 532 ? 46.057  96.889  -3.250  1.00 63.17  ? 825  GLU   A CG    1 
ATOM   4797  C  CD    . GLU   C 3 532 ? 46.776  97.807  -2.280  1.00 72.50  ? 825  GLU   A CD    1 
ATOM   4798  O  OE1   . GLU   C 3 532 ? 46.541  97.668  -1.058  1.00 81.16  ? 825  GLU   A OE1   1 
ATOM   4799  O  OE2   . GLU   C 3 532 ? 47.560  98.666  -2.754  1.00 74.19  ? 825  GLU   A OE2   1 
ATOM   4800  N  N     . ASP   C 3 533 ? 45.239  92.295  -3.541  1.00 42.76  ? 826  ASP   A N     1 
ATOM   4801  C  CA    . ASP   C 3 533 ? 45.463  90.880  -3.349  1.00 41.34  ? 826  ASP   A CA    1 
ATOM   4802  C  C     . ASP   C 3 533 ? 44.198  90.130  -3.742  1.00 40.39  ? 826  ASP   A C     1 
ATOM   4803  O  O     . ASP   C 3 533 ? 43.153  90.739  -3.974  1.00 40.75  ? 826  ASP   A O     1 
ATOM   4804  C  CB    . ASP   C 3 533 ? 45.873  90.592  -1.907  1.00 41.77  ? 826  ASP   A CB    1 
ATOM   4805  C  CG    . ASP   C 3 533 ? 44.814  90.922  -0.877  1.00 44.65  ? 826  ASP   A CG    1 
ATOM   4806  O  OD1   . ASP   C 3 533 ? 43.846  90.144  -0.763  1.00 48.34  ? 826  ASP   A OD1   1 
ATOM   4807  O  OD2   . ASP   C 3 533 ? 44.965  91.962  -0.195  1.00 57.61  ? 826  ASP   A OD2   1 
ATOM   4808  N  N     . TRP   C 3 534 ? 44.309  88.800  -3.778  1.00 38.41  ? 827  TRP   A N     1 
ATOM   4809  C  CA    . TRP   C 3 534 ? 43.297  87.958  -4.390  1.00 39.92  ? 827  TRP   A CA    1 
ATOM   4810  C  C     . TRP   C 3 534 ? 42.057  87.879  -3.503  1.00 42.78  ? 827  TRP   A C     1 
ATOM   4811  O  O     . TRP   C 3 534 ? 40.944  87.687  -3.998  1.00 38.87  ? 827  TRP   A O     1 
ATOM   4812  C  CB    . TRP   C 3 534 ? 43.890  86.576  -4.678  1.00 38.18  ? 827  TRP   A CB    1 
ATOM   4813  C  CG    . TRP   C 3 534 ? 43.090  85.715  -5.599  1.00 37.31  ? 827  TRP   A CG    1 
ATOM   4814  C  CD1   . TRP   C 3 534 ? 41.874  85.984  -6.156  1.00 38.06  ? 827  TRP   A CD1   1 
ATOM   4815  C  CD2   . TRP   C 3 534 ? 43.457  84.399  -6.057  1.00 39.21  ? 827  TRP   A CD2   1 
ATOM   4816  N  NE1   . TRP   C 3 534 ? 41.456  84.926  -6.923  1.00 38.75  ? 827  TRP   A NE1   1 
ATOM   4817  C  CE2   . TRP   C 3 534 ? 42.414  83.945  -6.899  1.00 37.61  ? 827  TRP   A CE2   1 
ATOM   4818  C  CE3   . TRP   C 3 534 ? 44.550  83.559  -5.832  1.00 35.04  ? 827  TRP   A CE3   1 
ATOM   4819  C  CZ2   . TRP   C 3 534 ? 42.445  82.699  -7.522  1.00 37.79  ? 827  TRP   A CZ2   1 
ATOM   4820  C  CZ3   . TRP   C 3 534 ? 44.586  82.334  -6.465  1.00 37.28  ? 827  TRP   A CZ3   1 
ATOM   4821  C  CH2   . TRP   C 3 534 ? 43.542  81.904  -7.281  1.00 38.98  ? 827  TRP   A CH2   1 
ATOM   4822  N  N     . LEU   C 3 535 ? 42.247  87.992  -2.182  1.00 45.41  ? 828  LEU   A N     1 
ATOM   4823  C  CA    . LEU   C 3 535 ? 41.104  87.964  -1.285  1.00 43.97  ? 828  LEU   A CA    1 
ATOM   4824  C  C     . LEU   C 3 535 ? 40.287  89.237  -1.483  1.00 42.76  ? 828  LEU   A C     1 
ATOM   4825  O  O     . LEU   C 3 535 ? 39.067  89.164  -1.616  1.00 39.28  ? 828  LEU   A O     1 
ATOM   4826  C  CB    . LEU   C 3 535 ? 41.552  87.817  0.173   1.00 46.74  ? 828  LEU   A CB    1 
ATOM   4827  C  CG    . LEU   C 3 535 ? 40.405  87.708  1.183   1.00 51.62  ? 828  LEU   A CG    1 
ATOM   4828  C  CD1   . LEU   C 3 535 ? 39.683  86.361  1.073   1.00 50.58  ? 828  LEU   A CD1   1 
ATOM   4829  C  CD2   . LEU   C 3 535 ? 40.903  87.943  2.607   1.00 53.10  ? 828  LEU   A CD2   1 
ATOM   4830  N  N     . SER   C 3 536 ? 40.957  90.396  -1.475  1.00 40.63  ? 829  SER   A N     1 
ATOM   4831  C  CA    . SER   C 3 536 ? 40.235  91.655  -1.514  1.00 47.46  ? 829  SER   A CA    1 
ATOM   4832  C  C     . SER   C 3 536 ? 39.601  91.876  -2.892  1.00 49.08  ? 829  SER   A C     1 
ATOM   4833  O  O     . SER   C 3 536 ? 38.564  92.528  -2.999  1.00 49.27  ? 829  SER   A O     1 
ATOM   4834  C  CB    . SER   C 3 536 ? 41.107  92.809  -1.091  1.00 44.06  ? 829  SER   A CB    1 
ATOM   4835  O  OG    . SER   C 3 536 ? 42.280  92.843  -1.862  1.00 47.93  ? 829  SER   A OG    1 
ATOM   4836  N  N     . ALA   C 3 537 ? 40.178  91.275  -3.939  1.00 48.22  ? 830  ALA   A N     1 
ATOM   4837  C  CA    . ALA   C 3 537 ? 39.593  91.358  -5.269  1.00 50.00  ? 830  ALA   A CA    1 
ATOM   4838  C  C     . ALA   C 3 537 ? 38.295  90.547  -5.405  1.00 52.05  ? 830  ALA   A C     1 
ATOM   4839  O  O     . ALA   C 3 537 ? 37.729  90.513  -6.489  1.00 62.71  ? 830  ALA   A O     1 
ATOM   4840  C  CB    . ALA   C 3 537 ? 40.610  90.913  -6.289  1.00 49.15  ? 830  ALA   A CB    1 
ATOM   4841  N  N     . LYS   C 3 538 ? 37.814  89.887  -4.343  1.00 50.40  ? 831  LYS   A N     1 
ATOM   4842  C  CA    . LYS   C 3 538 ? 36.593  89.095  -4.416  1.00 53.64  ? 831  LYS   A CA    1 
ATOM   4843  C  C     . LYS   C 3 538 ? 35.623  89.444  -3.283  1.00 54.71  ? 831  LYS   A C     1 
ATOM   4844  O  O     . LYS   C 3 538 ? 34.686  88.692  -3.040  1.00 61.44  ? 831  LYS   A O     1 
ATOM   4845  C  CB    . LYS   C 3 538 ? 36.936  87.599  -4.344  1.00 55.81  ? 831  LYS   A CB    1 
ATOM   4846  C  CG    . LYS   C 3 538 ? 37.823  87.066  -5.468  1.00 61.00  ? 831  LYS   A CG    1 
ATOM   4847  C  CD    . LYS   C 3 538 ? 37.135  86.128  -6.444  1.00 61.00  ? 831  LYS   A CD    1 
ATOM   4848  C  CE    . LYS   C 3 538 ? 37.195  84.684  -5.995  1.00 64.49  ? 831  LYS   A CE    1 
ATOM   4849  N  NZ    . LYS   C 3 538 ? 36.410  83.787  -6.881  1.00 60.08  ? 831  LYS   A NZ    1 
ATOM   4850  N  N     . GLU   C 3 539 ? 35.805  90.580  -2.599  1.00 60.33  ? 832  GLU   A N     1 
ATOM   4851  C  CA    . GLU   C 3 539 ? 35.005  90.898  -1.417  1.00 65.64  ? 832  GLU   A CA    1 
ATOM   4852  C  C     . GLU   C 3 539 ? 33.613  91.411  -1.813  1.00 65.44  ? 832  GLU   A C     1 
ATOM   4853  O  O     . GLU   C 3 539 ? 33.488  91.894  -2.957  1.00 76.18  ? 832  GLU   A O     1 
ATOM   4854  C  CB    . GLU   C 3 539 ? 35.730  91.925  -0.543  1.00 70.17  ? 832  GLU   A CB    1 
ATOM   4855  C  CG    . GLU   C 3 539 ? 36.615  91.277  0.504   1.00 72.27  ? 832  GLU   A CG    1 
ATOM   4856  C  CD    . GLU   C 3 539 ? 37.656  92.185  1.138   1.00 80.24  ? 832  GLU   A CD    1 
ATOM   4857  O  OE1   . GLU   C 3 539 ? 37.632  93.408  0.845   1.00 78.11  ? 832  GLU   A OE1   1 
ATOM   4858  O  OE2   . GLU   C 3 539 ? 38.512  91.659  1.905   1.00 76.00  ? 832  GLU   A OE2   1 
ATOM   4859  O  "O5'" . DG    D 1 1   ? -1.391  120.763 -65.507 1.00 84.62  ? 101  DG    E "O5'" 1 
ATOM   4860  C  "C5'" . DG    D 1 1   ? -1.039  121.615 -64.380 1.00 87.22  ? 101  DG    E "C5'" 1 
ATOM   4861  C  "C4'" . DG    D 1 1   ? -1.217  120.884 -63.066 1.00 84.54  ? 101  DG    E "C4'" 1 
ATOM   4862  O  "O4'" . DG    D 1 1   ? -2.276  119.901 -63.157 1.00 82.59  ? 101  DG    E "O4'" 1 
ATOM   4863  C  "C3'" . DG    D 1 1   ? 0.014   120.133 -62.560 1.00 81.28  ? 101  DG    E "C3'" 1 
ATOM   4864  O  "O3'" . DG    D 1 1   ? 0.068   120.308 -61.146 1.00 86.36  ? 101  DG    E "O3'" 1 
ATOM   4865  C  "C2'" . DG    D 1 1   ? -0.278  118.688 -62.958 1.00 78.30  ? 101  DG    E "C2'" 1 
ATOM   4866  C  "C1'" . DG    D 1 1   ? -1.783  118.616 -62.777 1.00 72.50  ? 101  DG    E "C1'" 1 
ATOM   4867  N  N9    . DG    D 1 1   ? -2.471  117.614 -63.593 1.00 61.59  ? 101  DG    E N9    1 
ATOM   4868  C  C8    . DG    D 1 1   ? -2.350  117.319 -64.931 1.00 60.19  ? 101  DG    E C8    1 
ATOM   4869  N  N7    . DG    D 1 1   ? -3.155  116.359 -65.330 1.00 57.81  ? 101  DG    E N7    1 
ATOM   4870  C  C5    . DG    D 1 1   ? -3.861  116.005 -64.182 1.00 55.52  ? 101  DG    E C5    1 
ATOM   4871  C  C6    . DG    D 1 1   ? -4.883  115.036 -63.991 1.00 49.91  ? 101  DG    E C6    1 
ATOM   4872  O  O6    . DG    D 1 1   ? -5.403  114.277 -64.821 1.00 48.72  ? 101  DG    E O6    1 
ATOM   4873  N  N1    . DG    D 1 1   ? -5.304  114.997 -62.663 1.00 52.03  ? 101  DG    E N1    1 
ATOM   4874  C  C2    . DG    D 1 1   ? -4.830  115.802 -61.654 1.00 54.89  ? 101  DG    E C2    1 
ATOM   4875  N  N2    . DG    D 1 1   ? -5.370  115.619 -60.443 1.00 54.56  ? 101  DG    E N2    1 
ATOM   4876  N  N3    . DG    D 1 1   ? -3.886  116.729 -61.824 1.00 54.88  ? 101  DG    E N3    1 
ATOM   4877  C  C4    . DG    D 1 1   ? -3.450  116.776 -63.109 1.00 58.79  ? 101  DG    E C4    1 
ATOM   4878  P  P     . DA    D 1 2   ? 1.351   119.706 -60.393 1.00 90.83  ? 102  DA    E P     1 
ATOM   4879  O  OP1   . DA    D 1 2   ? 1.812   120.722 -59.385 1.00 86.77  ? 102  DA    E OP1   1 
ATOM   4880  O  OP2   . DA    D 1 2   ? 2.325   119.147 -61.400 1.00 90.78  ? 102  DA    E OP2   1 
ATOM   4881  O  "O5'" . DA    D 1 2   ? 0.664   118.484 -59.606 1.00 87.64  ? 102  DA    E "O5'" 1 
ATOM   4882  C  "C5'" . DA    D 1 2   ? -0.155  118.797 -58.448 1.00 87.03  ? 102  DA    E "C5'" 1 
ATOM   4883  C  "C4'" . DA    D 1 2   ? -0.548  117.523 -57.740 1.00 83.32  ? 102  DA    E "C4'" 1 
ATOM   4884  O  "O4'" . DA    D 1 2   ? -1.292  116.677 -58.644 1.00 79.52  ? 102  DA    E "O4'" 1 
ATOM   4885  C  "C3'" . DA    D 1 2   ? 0.624   116.689 -57.222 1.00 83.98  ? 102  DA    E "C3'" 1 
ATOM   4886  O  "O3'" . DA    D 1 2   ? 0.241   116.191 -55.935 1.00 87.06  ? 102  DA    E "O3'" 1 
ATOM   4887  C  "C2'" . DA    D 1 2   ? 0.785   115.622 -58.309 1.00 75.84  ? 102  DA    E "C2'" 1 
ATOM   4888  C  "C1'" . DA    D 1 2   ? -0.649  115.408 -58.761 1.00 73.21  ? 102  DA    E "C1'" 1 
ATOM   4889  N  N9    . DA    D 1 2   ? -0.828  114.946 -60.139 1.00 65.14  ? 102  DA    E N9    1 
ATOM   4890  C  C8    . DA    D 1 2   ? -0.197  115.306 -61.308 1.00 61.94  ? 102  DA    E C8    1 
ATOM   4891  N  N7    . DA    D 1 2   ? -0.665  114.682 -62.366 1.00 57.42  ? 102  DA    E N7    1 
ATOM   4892  C  C5    . DA    D 1 2   ? -1.681  113.873 -61.869 1.00 53.10  ? 102  DA    E C5    1 
ATOM   4893  C  C6    . DA    D 1 2   ? -2.577  112.972 -62.487 1.00 54.13  ? 102  DA    E C6    1 
ATOM   4894  N  N6    . DA    D 1 2   ? -2.592  112.708 -63.791 1.00 56.78  ? 102  DA    E N6    1 
ATOM   4895  N  N1    . DA    D 1 2   ? -3.470  112.329 -61.693 1.00 53.48  ? 102  DA    E N1    1 
ATOM   4896  C  C2    . DA    D 1 2   ? -3.457  112.582 -60.375 1.00 54.92  ? 102  DA    E C2    1 
ATOM   4897  N  N3    . DA    D 1 2   ? -2.670  113.408 -59.685 1.00 58.35  ? 102  DA    E N3    1 
ATOM   4898  C  C4    . DA    D 1 2   ? -1.796  114.034 -60.497 1.00 57.45  ? 102  DA    E C4    1 
ATOM   4899  P  P     . DC    D 1 3   ? 1.417   115.434 -55.141 1.00 99.49  ? 103  DC    E P     1 
ATOM   4900  O  OP1   . DC    D 1 3   ? 1.693   116.205 -53.878 1.00 83.92  ? 103  DC    E OP1   1 
ATOM   4901  O  OP2   . DC    D 1 3   ? 2.538   115.190 -56.124 1.00 87.06  ? 103  DC    E OP2   1 
ATOM   4902  O  "O5'" . DC    D 1 3   ? 0.713   114.027 -54.780 1.00 84.22  ? 103  DC    E "O5'" 1 
ATOM   4903  C  "C5'" . DC    D 1 3   ? -0.698  113.863 -55.092 1.00 84.60  ? 103  DC    E "C5'" 1 
ATOM   4904  C  "C4'" . DC    D 1 3   ? -1.040  112.420 -55.391 1.00 79.66  ? 103  DC    E "C4'" 1 
ATOM   4905  O  "O4'" . DC    D 1 3   ? -1.198  112.218 -56.817 1.00 72.82  ? 103  DC    E "O4'" 1 
ATOM   4906  C  "C3'" . DC    D 1 3   ? -0.039  111.366 -54.912 1.00 78.25  ? 103  DC    E "C3'" 1 
ATOM   4907  O  "O3'" . DC    D 1 3   ? -0.789  110.521 -54.035 1.00 76.72  ? 103  DC    E "O3'" 1 
ATOM   4908  C  "C2'" . DC    D 1 3   ? 0.411   110.660 -56.189 1.00 71.76  ? 103  DC    E "C2'" 1 
ATOM   4909  C  "C1'" . DC    D 1 3   ? -0.744  110.923 -57.145 1.00 65.70  ? 103  DC    E "C1'" 1 
ATOM   4910  N  N1    . DC    D 1 3   ? -0.397  110.938 -58.590 1.00 56.74  ? 103  DC    E N1    1 
ATOM   4911  C  C2    . DC    D 1 3   ? -1.166  110.187 -59.488 1.00 56.10  ? 103  DC    E C2    1 
ATOM   4912  O  O2    . DC    D 1 3   ? -2.109  109.505 -59.058 1.00 57.53  ? 103  DC    E O2    1 
ATOM   4913  N  N3    . DC    D 1 3   ? -0.846  110.208 -60.806 1.00 53.49  ? 103  DC    E N3    1 
ATOM   4914  C  C4    . DC    D 1 3   ? 0.192   110.935 -61.244 1.00 48.56  ? 103  DC    E C4    1 
ATOM   4915  N  N4    . DC    D 1 3   ? 0.451   110.914 -62.544 1.00 48.64  ? 103  DC    E N4    1 
ATOM   4916  C  C5    . DC    D 1 3   ? 0.966   111.726 -60.354 1.00 45.67  ? 103  DC    E C5    1 
ATOM   4917  C  C6    . DC    D 1 3   ? 0.650   111.687 -59.047 1.00 50.26  ? 103  DC    E C6    1 
ATOM   4918  P  P     . DC    D 1 4   ? 0.061   109.567 -53.061 1.00 71.07  ? 104  DC    E P     1 
ATOM   4919  O  OP1   . DC    D 1 4   ? -0.778  109.162 -51.881 1.00 73.58  ? 104  DC    E OP1   1 
ATOM   4920  O  OP2   . DC    D 1 4   ? 1.443   110.145 -52.888 1.00 63.24  ? 104  DC    E OP2   1 
ATOM   4921  O  "O5'" . DC    D 1 4   ? 0.084   108.261 -53.992 1.00 65.75  ? 104  DC    E "O5'" 1 
ATOM   4922  C  "C5'" . DC    D 1 4   ? -1.177  107.591 -54.214 1.00 62.04  ? 104  DC    E "C5'" 1 
ATOM   4923  C  "C4'" . DC    D 1 4   ? -0.977  106.456 -55.183 1.00 61.07  ? 104  DC    E "C4'" 1 
ATOM   4924  O  "O4'" . DC    D 1 4   ? -0.594  106.974 -56.481 1.00 59.20  ? 104  DC    E "O4'" 1 
ATOM   4925  C  "C3'" . DC    D 1 4   ? 0.117   105.464 -54.777 1.00 59.82  ? 104  DC    E "C3'" 1 
ATOM   4926  O  "O3'" . DC    D 1 4   ? -0.316  104.156 -55.128 1.00 64.26  ? 104  DC    E "O3'" 1 
ATOM   4927  C  "C2'" . DC    D 1 4   ? 1.281   105.880 -55.665 1.00 56.42  ? 104  DC    E "C2'" 1 
ATOM   4928  C  "C1'" . DC    D 1 4   ? 0.529   106.241 -56.938 1.00 58.88  ? 104  DC    E "C1'" 1 
ATOM   4929  N  N1    . DC    D 1 4   ? 1.274   107.045 -57.941 1.00 49.62  ? 104  DC    E N1    1 
ATOM   4930  C  C2    . DC    D 1 4   ? 0.957   106.873 -59.296 1.00 50.32  ? 104  DC    E C2    1 
ATOM   4931  O  O2    . DC    D 1 4   ? 0.066   106.063 -59.618 1.00 46.80  ? 104  DC    E O2    1 
ATOM   4932  N  N3    . DC    D 1 4   ? 1.640   107.592 -60.223 1.00 49.64  ? 104  DC    E N3    1 
ATOM   4933  C  C4    . DC    D 1 4   ? 2.597   108.447 -59.850 1.00 53.38  ? 104  DC    E C4    1 
ATOM   4934  N  N4    . DC    D 1 4   ? 3.214   109.121 -60.808 1.00 52.44  ? 104  DC    E N4    1 
ATOM   4935  C  C5    . DC    D 1 4   ? 2.938   108.631 -58.476 1.00 54.08  ? 104  DC    E C5    1 
ATOM   4936  C  C6    . DC    D 1 4   ? 2.257   107.916 -57.565 1.00 53.27  ? 104  DC    E C6    1 
ATOM   4937  P  P     . DA    D 1 5   ? -0.557  103.151 -53.901 1.00 59.07  ? 105  DA    E P     1 
ATOM   4938  O  OP1   . DA    D 1 5   ? -1.656  103.710 -53.047 1.00 64.27  ? 105  DA    E OP1   1 
ATOM   4939  O  OP2   . DA    D 1 5   ? 0.795   102.849 -53.301 1.00 64.63  ? 105  DA    E OP2   1 
ATOM   4940  O  "O5'" . DA    D 1 5   ? -1.105  101.888 -54.739 1.00 51.40  ? 105  DA    E "O5'" 1 
ATOM   4941  C  "C5'" . DA    D 1 5   ? -2.428  101.986 -55.335 1.00 59.81  ? 105  DA    E "C5'" 1 
ATOM   4942  C  "C4'" . DA    D 1 5   ? -2.469  101.241 -56.646 1.00 57.91  ? 105  DA    E "C4'" 1 
ATOM   4943  O  "O4'" . DA    D 1 5   ? -1.691  101.941 -57.648 1.00 60.96  ? 105  DA    E "O4'" 1 
ATOM   4944  C  "C3'" . DA    D 1 5   ? -1.895  99.828  -56.595 1.00 59.04  ? 105  DA    E "C3'" 1 
ATOM   4945  O  "O3'" . DA    D 1 5   ? -2.608  99.084  -57.582 1.00 55.76  ? 105  DA    E "O3'" 1 
ATOM   4946  C  "C2'" . DA    D 1 5   ? -0.432  100.070 -56.965 1.00 58.09  ? 105  DA    E "C2'" 1 
ATOM   4947  C  "C1'" . DA    D 1 5   ? -0.579  101.130 -58.054 1.00 57.95  ? 105  DA    E "C1'" 1 
ATOM   4948  N  N9    . DA    D 1 5   ? 0.565   102.027 -58.256 1.00 52.59  ? 105  DA    E N9    1 
ATOM   4949  C  C8    . DA    D 1 5   ? 1.334   102.633 -57.292 1.00 51.55  ? 105  DA    E C8    1 
ATOM   4950  N  N7    . DA    D 1 5   ? 2.260   103.420 -57.776 1.00 48.83  ? 105  DA    E N7    1 
ATOM   4951  C  C5    . DA    D 1 5   ? 2.070   103.366 -59.148 1.00 50.32  ? 105  DA    E C5    1 
ATOM   4952  C  C6    . DA    D 1 5   ? 2.729   104.001 -60.218 1.00 48.66  ? 105  DA    E C6    1 
ATOM   4953  N  N6    . DA    D 1 5   ? 3.743   104.843 -60.063 1.00 49.73  ? 105  DA    E N6    1 
ATOM   4954  N  N1    . DA    D 1 5   ? 2.303   103.724 -61.469 1.00 49.27  ? 105  DA    E N1    1 
ATOM   4955  C  C2    . DA    D 1 5   ? 1.282   102.869 -61.624 1.00 53.12  ? 105  DA    E C2    1 
ATOM   4956  N  N3    . DA    D 1 5   ? 0.584   102.216 -60.698 1.00 53.11  ? 105  DA    E N3    1 
ATOM   4957  C  C4    . DA    D 1 5   ? 1.032   102.507 -59.462 1.00 52.16  ? 105  DA    E C4    1 
ATOM   4958  P  P     . DC    D 1 6   ? -2.440  97.490  -57.524 1.00 60.98  ? 106  DC    E P     1 
ATOM   4959  O  OP1   . DC    D 1 6   ? -3.708  96.830  -57.985 1.00 59.90  ? 106  DC    E OP1   1 
ATOM   4960  O  OP2   . DC    D 1 6   ? -1.746  97.076  -56.250 1.00 67.17  ? 106  DC    E OP2   1 
ATOM   4961  O  "O5'" . DC    D 1 6   ? -1.361  97.216  -58.683 1.00 61.91  ? 106  DC    E "O5'" 1 
ATOM   4962  C  "C5'" . DC    D 1 6   ? -1.724  97.518  -60.046 1.00 61.42  ? 106  DC    E "C5'" 1 
ATOM   4963  C  "C4'" . DC    D 1 6   ? -0.480  97.662  -60.889 1.00 56.42  ? 106  DC    E "C4'" 1 
ATOM   4964  O  "O4'" . DC    D 1 6   ? 0.300   98.820  -60.522 1.00 48.21  ? 106  DC    E "O4'" 1 
ATOM   4965  C  "C3'" . DC    D 1 6   ? 0.503   96.503  -60.800 1.00 50.70  ? 106  DC    E "C3'" 1 
ATOM   4966  O  "O3'" . DC    D 1 6   ? 0.039   95.578  -61.764 1.00 52.20  ? 106  DC    E "O3'" 1 
ATOM   4967  C  "C2'" . DC    D 1 6   ? 1.839   97.159  -61.138 1.00 51.02  ? 106  DC    E "C2'" 1 
ATOM   4968  C  "C1'" . DC    D 1 6   ? 1.536   98.656  -61.175 1.00 48.40  ? 106  DC    E "C1'" 1 
ATOM   4969  N  N1    . DC    D 1 6   ? 2.544   99.496  -60.488 1.00 46.33  ? 106  DC    E N1    1 
ATOM   4970  C  C2    . DC    D 1 6   ? 3.397   100.287 -61.261 1.00 45.08  ? 106  DC    E C2    1 
ATOM   4971  O  O2    . DC    D 1 6   ? 3.257   100.282 -62.498 1.00 43.72  ? 106  DC    E O2    1 
ATOM   4972  N  N3    . DC    D 1 6   ? 4.334   101.037 -60.639 1.00 41.33  ? 106  DC    E N3    1 
ATOM   4973  C  C4    . DC    D 1 6   ? 4.469   100.991 -59.312 1.00 43.74  ? 106  DC    E C4    1 
ATOM   4974  N  N4    . DC    D 1 6   ? 5.392   101.750 -58.756 1.00 42.56  ? 106  DC    E N4    1 
ATOM   4975  C  C5    . DC    D 1 6   ? 3.630   100.175 -58.513 1.00 47.90  ? 106  DC    E C5    1 
ATOM   4976  C  C6    . DC    D 1 6   ? 2.686   99.450  -59.137 1.00 48.96  ? 106  DC    E C6    1 
ATOM   4977  P  P     . DG    D 1 7   ? 0.858   94.207  -61.909 1.00 55.85  ? 107  DG    E P     1 
ATOM   4978  O  OP1   . DG    D 1 7   ? -0.004  93.226  -62.641 1.00 55.57  ? 107  DG    E OP1   1 
ATOM   4979  O  OP2   . DG    D 1 7   ? 1.570   93.861  -60.625 1.00 59.03  ? 107  DG    E OP2   1 
ATOM   4980  O  "O5'" . DG    D 1 7   ? 1.963   94.635  -62.995 1.00 61.02  ? 107  DG    E "O5'" 1 
ATOM   4981  C  "C5'" . DG    D 1 7   ? 1.509   94.881  -64.352 1.00 56.72  ? 107  DG    E "C5'" 1 
ATOM   4982  C  "C4'" . DG    D 1 7   ? 2.680   95.189  -65.252 1.00 46.98  ? 107  DG    E "C4'" 1 
ATOM   4983  O  "O4'" . DG    D 1 7   ? 3.456   96.271  -64.690 1.00 45.79  ? 107  DG    E "O4'" 1 
ATOM   4984  C  "C3'" . DG    D 1 7   ? 3.645   94.030  -65.469 1.00 45.78  ? 107  DG    E "C3'" 1 
ATOM   4985  O  "O3'" . DG    D 1 7   ? 4.091   94.190  -66.788 1.00 43.82  ? 107  DG    E "O3'" 1 
ATOM   4986  C  "C2'" . DG    D 1 7   ? 4.744   94.295  -64.444 1.00 47.09  ? 107  DG    E "C2'" 1 
ATOM   4987  C  "C1'" . DG    D 1 7   ? 4.788   95.817  -64.416 1.00 48.29  ? 107  DG    E "C1'" 1 
ATOM   4988  N  N9    . DG    D 1 7   ? 5.209   96.408  -63.143 1.00 42.55  ? 107  DG    E N9    1 
ATOM   4989  C  C8    . DG    D 1 7   ? 4.835   96.039  -61.875 1.00 47.61  ? 107  DG    E C8    1 
ATOM   4990  N  N7    . DG    D 1 7   ? 5.362   96.785  -60.933 1.00 45.39  ? 107  DG    E N7    1 
ATOM   4991  C  C5    . DG    D 1 7   ? 6.114   97.725  -61.630 1.00 42.86  ? 107  DG    E C5    1 
ATOM   4992  C  C6    . DG    D 1 7   ? 6.930   98.777  -61.144 1.00 42.02  ? 107  DG    E C6    1 
ATOM   4993  O  O6    . DG    D 1 7   ? 7.137   99.118  -59.968 1.00 38.94  ? 107  DG    E O6    1 
ATOM   4994  N  N1    . DG    D 1 7   ? 7.538   99.469  -62.192 1.00 42.23  ? 107  DG    E N1    1 
ATOM   4995  C  C2    . DG    D 1 7   ? 7.399   99.186  -63.527 1.00 42.28  ? 107  DG    E C2    1 
ATOM   4996  N  N2    . DG    D 1 7   ? 8.078   99.970  -64.373 1.00 44.05  ? 107  DG    E N2    1 
ATOM   4997  N  N3    . DG    D 1 7   ? 6.662   98.178  -63.993 1.00 44.03  ? 107  DG    E N3    1 
ATOM   4998  C  C4    . DG    D 1 7   ? 6.042   97.496  -62.990 1.00 44.62  ? 107  DG    E C4    1 
ATOM   4999  P  P     . DG    D 1 8   ? 4.818   92.942  -67.471 1.00 51.57  ? 108  DG    E P     1 
ATOM   5000  O  OP1   . DG    D 1 8   ? 4.648   93.128  -68.960 1.00 49.55  ? 108  DG    E OP1   1 
ATOM   5001  O  OP2   . DG    D 1 8   ? 4.418   91.631  -66.840 1.00 53.98  ? 108  DG    E OP2   1 
ATOM   5002  O  "O5'" . DG    D 1 8   ? 6.333   93.259  -67.040 1.00 50.00  ? 108  DG    E "O5'" 1 
ATOM   5003  C  "C5'" . DG    D 1 8   ? 7.064   94.255  -67.785 1.00 50.15  ? 108  DG    E "C5'" 1 
ATOM   5004  C  "C4'" . DG    D 1 8   ? 8.270   94.715  -67.004 1.00 43.21  ? 108  DG    E "C4'" 1 
ATOM   5005  O  "O4'" . DG    D 1 8   ? 7.893   95.204  -65.703 1.00 42.40  ? 108  DG    E "O4'" 1 
ATOM   5006  C  "C3'" . DG    D 1 8   ? 9.304   93.619  -66.747 1.00 43.29  ? 108  DG    E "C3'" 1 
ATOM   5007  O  "O3'" . DG    D 1 8   ? 10.350  93.801  -67.686 1.00 43.85  ? 108  DG    E "O3'" 1 
ATOM   5008  C  "C2'" . DG    D 1 8   ? 9.768   93.860  -65.312 1.00 40.42  ? 108  DG    E "C2'" 1 
ATOM   5009  C  "C1'" . DG    D 1 8   ? 9.113   95.185  -64.960 1.00 41.39  ? 108  DG    E "C1'" 1 
ATOM   5010  N  N9    . DG    D 1 8   ? 8.861   95.336  -63.530 1.00 37.23  ? 108  DG    E N9    1 
ATOM   5011  C  C8    . DG    D 1 8   ? 8.079   94.555  -62.716 1.00 35.66  ? 108  DG    E C8    1 
ATOM   5012  N  N7    . DG    D 1 8   ? 8.078   94.949  -61.460 1.00 35.19  ? 108  DG    E N7    1 
ATOM   5013  C  C5    . DG    D 1 8   ? 8.958   96.025  -61.432 1.00 34.01  ? 108  DG    E C5    1 
ATOM   5014  C  C6    . DG    D 1 8   ? 9.395   96.823  -60.344 1.00 35.59  ? 108  DG    E C6    1 
ATOM   5015  O  O6    . DG    D 1 8   ? 9.068   96.770  -59.149 1.00 40.56  ? 108  DG    E O6    1 
ATOM   5016  N  N1    . DG    D 1 8   ? 10.299  97.795  -60.762 1.00 37.39  ? 108  DG    E N1    1 
ATOM   5017  C  C2    . DG    D 1 8   ? 10.738  97.970  -62.051 1.00 36.69  ? 108  DG    E C2    1 
ATOM   5018  N  N2    . DG    D 1 8   ? 11.608  98.964  -62.238 1.00 37.57  ? 108  DG    E N2    1 
ATOM   5019  N  N3    . DG    D 1 8   ? 10.352  97.212  -63.081 1.00 35.62  ? 108  DG    E N3    1 
ATOM   5020  C  C4    . DG    D 1 8   ? 9.454   96.268  -62.702 1.00 37.72  ? 108  DG    E C4    1 
ATOM   5021  P  P     . DC    D 1 9   ? 11.457  92.644  -67.652 1.00 44.03  ? 109  DC    E P     1 
ATOM   5022  O  OP1   . DC    D 1 9   ? 12.261  92.591  -68.929 1.00 44.87  ? 109  DC    E OP1   1 
ATOM   5023  O  OP2   . DC    D 1 9   ? 10.818  91.382  -67.142 1.00 40.52  ? 109  DC    E OP2   1 
ATOM   5024  O  "O5'" . DC    D 1 9   ? 12.433  93.219  -66.516 1.00 45.56  ? 109  DC    E "O5'" 1 
ATOM   5025  C  "C5'" . DC    D 1 9   ? 13.117  94.467  -66.751 1.00 47.05  ? 109  DC    E "C5'" 1 
ATOM   5026  C  "C4'" . DC    D 1 9   ? 14.025  94.741  -65.585 1.00 41.47  ? 109  DC    E "C4'" 1 
ATOM   5027  O  "O4'" . DC    D 1 9   ? 13.215  95.037  -64.425 1.00 46.07  ? 109  DC    E "O4'" 1 
ATOM   5028  C  "C3'" . DC    D 1 9   ? 14.933  93.569  -65.188 1.00 40.82  ? 109  DC    E "C3'" 1 
ATOM   5029  O  "O3'" . DC    D 1 9   ? 16.213  94.069  -64.821 1.00 40.19  ? 109  DC    E "O3'" 1 
ATOM   5030  C  "C2'" . DC    D 1 9   ? 14.256  93.026  -63.941 1.00 38.46  ? 109  DC    E "C2'" 1 
ATOM   5031  C  "C1'" . DC    D 1 9   ? 13.767  94.333  -63.334 1.00 38.73  ? 109  DC    E "C1'" 1 
ATOM   5032  N  N1    . DC    D 1 9   ? 12.784  94.190  -62.232 1.00 36.29  ? 109  DC    E N1    1 
ATOM   5033  C  C2    . DC    D 1 9   ? 12.918  95.024  -61.115 1.00 37.19  ? 109  DC    E C2    1 
ATOM   5034  O  O2    . DC    D 1 9   ? 13.777  95.918  -61.115 1.00 38.53  ? 109  DC    E O2    1 
ATOM   5035  N  N3    . DC    D 1 9   ? 12.104  94.850  -60.056 1.00 35.89  ? 109  DC    E N3    1 
ATOM   5036  C  C4    . DC    D 1 9   ? 11.193  93.876  -60.062 1.00 38.13  ? 109  DC    E C4    1 
ATOM   5037  N  N4    . DC    D 1 9   ? 10.416  93.774  -58.993 1.00 36.42  ? 109  DC    E N4    1 
ATOM   5038  C  C5    . DC    D 1 9   ? 11.040  93.011  -61.181 1.00 35.72  ? 109  DC    E C5    1 
ATOM   5039  C  C6    . DC    D 1 9   ? 11.850  93.199  -62.236 1.00 36.88  ? 109  DC    E C6    1 
ATOM   5040  P  P     . DG    D 1 10  ? 17.472  93.274  -65.414 1.00 38.71  ? 110  DG    E P     1 
ATOM   5041  O  OP1   . DG    D 1 10  ? 17.983  93.960  -66.645 1.00 44.19  ? 110  DG    E OP1   1 
ATOM   5042  O  OP2   . DG    D 1 10  ? 17.144  91.817  -65.393 1.00 36.47  ? 110  DG    E OP2   1 
ATOM   5043  O  "O5'" . DG    D 1 10  ? 18.491  93.565  -64.210 1.00 35.51  ? 110  DG    E "O5'" 1 
ATOM   5044  C  "C5'" . DG    D 1 10  ? 19.389  94.674  -64.319 1.00 34.41  ? 110  DG    E "C5'" 1 
ATOM   5045  C  "C4'" . DG    D 1 10  ? 19.704  95.210  -62.952 1.00 32.56  ? 110  DG    E "C4'" 1 
ATOM   5046  O  "O4'" . DG    D 1 10  ? 18.528  95.795  -62.355 1.00 32.70  ? 110  DG    E "O4'" 1 
ATOM   5047  C  "C3'" . DG    D 1 10  ? 20.174  94.168  -61.943 1.00 32.70  ? 110  DG    E "C3'" 1 
ATOM   5048  O  "O3'" . DG    D 1 10  ? 21.531  93.890  -62.176 1.00 32.98  ? 110  DG    E "O3'" 1 
ATOM   5049  C  "C2'" . DG    D 1 10  ? 19.959  94.943  -60.653 1.00 31.48  ? 110  DG    E "C2'" 1 
ATOM   5050  C  "C1'" . DG    D 1 10  ? 18.598  95.561  -60.941 1.00 33.87  ? 110  DG    E "C1'" 1 
ATOM   5051  N  N9    . DG    D 1 10  ? 17.472  94.699  -60.576 1.00 32.65  ? 110  DG    E N9    1 
ATOM   5052  C  C8    . DG    D 1 10  ? 16.705  93.886  -61.376 1.00 31.55  ? 110  DG    E C8    1 
ATOM   5053  N  N7    . DG    D 1 10  ? 15.723  93.298  -60.733 1.00 31.46  ? 110  DG    E N7    1 
ATOM   5054  C  C5    . DG    D 1 10  ? 15.852  93.758  -59.423 1.00 32.15  ? 110  DG    E C5    1 
ATOM   5055  C  C6    . DG    D 1 10  ? 15.093  93.462  -58.268 1.00 30.06  ? 110  DG    E C6    1 
ATOM   5056  O  O6    . DG    D 1 10  ? 14.110  92.718  -58.157 1.00 30.77  ? 110  DG    E O6    1 
ATOM   5057  N  N1    . DG    D 1 10  ? 15.563  94.170  -57.164 1.00 33.43  ? 110  DG    E N1    1 
ATOM   5058  C  C2    . DG    D 1 10  ? 16.647  95.011  -57.153 1.00 31.58  ? 110  DG    E C2    1 
ATOM   5059  N  N2    . DG    D 1 10  ? 16.956  95.591  -55.986 1.00 35.88  ? 110  DG    E N2    1 
ATOM   5060  N  N3    . DG    D 1 10  ? 17.358  95.298  -58.233 1.00 29.28  ? 110  DG    E N3    1 
ATOM   5061  C  C4    . DG    D 1 10  ? 16.913  94.634  -59.322 1.00 32.31  ? 110  DG    E C4    1 
ATOM   5062  P  P     . DC    D 1 11  ? 22.014  92.381  -61.951 1.00 31.07  ? 111  DC    E P     1 
ATOM   5063  O  OP1   . DC    D 1 11  ? 23.425  92.359  -62.475 1.00 31.06  ? 111  DC    E OP1   1 
ATOM   5064  O  OP2   . DC    D 1 11  ? 20.985  91.412  -62.424 1.00 30.22  ? 111  DC    E OP2   1 
ATOM   5065  O  "O5'" . DC    D 1 11  ? 21.973  92.364  -60.342 1.00 27.37  ? 111  DC    E "O5'" 1 
ATOM   5066  C  "C5'" . DC    D 1 11  ? 22.998  93.049  -59.607 1.00 30.42  ? 111  DC    E "C5'" 1 
ATOM   5067  C  "C4'" . DC    D 1 11  ? 22.666  92.990  -58.137 1.00 30.24  ? 111  DC    E "C4'" 1 
ATOM   5068  O  "O4'" . DC    D 1 11  ? 21.298  93.375  -57.907 1.00 30.70  ? 111  DC    E "O4'" 1 
ATOM   5069  C  "C3'" . DC    D 1 11  ? 22.752  91.605  -57.524 1.00 28.22  ? 111  DC    E "C3'" 1 
ATOM   5070  O  "O3'" . DC    D 1 11  ? 24.095  91.314  -57.185 1.00 30.12  ? 111  DC    E "O3'" 1 
ATOM   5071  C  "C2'" . DC    D 1 11  ? 21.928  91.785  -56.266 1.00 31.47  ? 111  DC    E "C2'" 1 
ATOM   5072  C  "C1'" . DC    D 1 11  ? 20.830  92.719  -56.739 1.00 31.53  ? 111  DC    E "C1'" 1 
ATOM   5073  N  N1    . DC    D 1 11  ? 19.574  92.024  -57.084 1.00 29.09  ? 111  DC    E N1    1 
ATOM   5074  C  C2    . DC    D 1 11  ? 18.690  91.685  -56.054 1.00 28.90  ? 111  DC    E C2    1 
ATOM   5075  O  O2    . DC    D 1 11  ? 18.969  91.941  -54.867 1.00 28.68  ? 111  DC    E O2    1 
ATOM   5076  N  N3    . DC    D 1 11  ? 17.540  91.082  -56.389 1.00 28.45  ? 111  DC    E N3    1 
ATOM   5077  C  C4    . DC    D 1 11  ? 17.252  90.802  -57.662 1.00 27.74  ? 111  DC    E C4    1 
ATOM   5078  N  N4    . DC    D 1 11  ? 16.088  90.227  -57.894 1.00 30.78  ? 111  DC    E N4    1 
ATOM   5079  C  C5    . DC    D 1 11  ? 18.136  91.124  -58.718 1.00 28.14  ? 111  DC    E C5    1 
ATOM   5080  C  C6    . DC    D 1 11  ? 19.285  91.727  -58.386 1.00 28.93  ? 111  DC    E C6    1 
HETATM 5081  N  N1    . DOC   D 1 12  ? 20.290  88.508  -53.933 1.00 26.25  ? 112  DOC   E N1    1 
HETATM 5082  C  C2    . DOC   D 1 12  ? 19.056  88.021  -53.528 1.00 27.28  ? 112  DOC   E C2    1 
HETATM 5083  N  N3    . DOC   D 1 12  ? 18.176  87.604  -54.452 1.00 25.48  ? 112  DOC   E N3    1 
HETATM 5084  C  C4    . DOC   D 1 12  ? 18.472  87.657  -55.744 1.00 26.21  ? 112  DOC   E C4    1 
HETATM 5085  C  C5    . DOC   D 1 12  ? 19.716  88.175  -56.188 1.00 23.51  ? 112  DOC   E C5    1 
HETATM 5086  C  C6    . DOC   D 1 12  ? 20.586  88.600  -55.261 1.00 25.20  ? 112  DOC   E C6    1 
HETATM 5087  O  O2    . DOC   D 1 12  ? 18.826  87.944  -52.318 1.00 31.69  ? 112  DOC   E O2    1 
HETATM 5088  N  N4    . DOC   D 1 12  ? 17.520  87.250  -56.588 1.00 28.11  ? 112  DOC   E N4    1 
HETATM 5089  C  "C1'" . DOC   D 1 12  ? 21.235  88.944  -52.886 1.00 26.42  ? 112  DOC   E "C1'" 1 
HETATM 5090  C  "C2'" . DOC   D 1 12  ? 22.105  87.811  -52.352 1.00 26.09  ? 112  DOC   E "C2'" 1 
HETATM 5091  C  "C3'" . DOC   D 1 12  ? 23.405  88.003  -53.097 1.00 25.72  ? 112  DOC   E "C3'" 1 
HETATM 5092  C  "C4'" . DOC   D 1 12  ? 23.475  89.502  -53.278 1.00 24.63  ? 112  DOC   E "C4'" 1 
HETATM 5093  O  "O4'" . DOC   D 1 12  ? 22.107  89.911  -53.460 1.00 24.85  ? 112  DOC   E "O4'" 1 
HETATM 5094  C  "C5'" . DOC   D 1 12  ? 24.257  89.985  -54.463 1.00 27.03  ? 112  DOC   E "C5'" 1 
HETATM 5095  O  "O5'" . DOC   D 1 12  ? 23.684  89.441  -55.683 1.00 27.14  ? 112  DOC   E "O5'" 1 
HETATM 5096  P  P     . DOC   D 1 12  ? 24.404  89.767  -57.100 1.00 26.99  ? 112  DOC   E P     1 
HETATM 5097  O  OP1   . DOC   D 1 12  ? 25.897  89.612  -56.877 1.00 23.85  ? 112  DOC   E OP1   1 
HETATM 5098  O  OP2   . DOC   D 1 12  ? 23.711  88.893  -58.142 1.00 26.67  ? 112  DOC   E OP2   1 
ATOM   5099  C  "C5'" . DA    E 2 1   ? -3.628  81.809  -57.754 1.00 137.76 ? 202  DA    F "C5'" 1 
ATOM   5100  C  "C4'" . DA    E 2 1   ? -2.916  82.140  -59.044 1.00 153.38 ? 202  DA    F "C4'" 1 
ATOM   5101  O  "O4'" . DA    E 2 1   ? -2.841  83.576  -59.201 1.00 150.77 ? 202  DA    F "O4'" 1 
ATOM   5102  C  "C3'" . DA    E 2 1   ? -1.466  81.661  -59.155 1.00 160.10 ? 202  DA    F "C3'" 1 
ATOM   5103  O  "O3'" . DA    E 2 1   ? -1.324  80.263  -59.496 1.00 169.87 ? 202  DA    F "O3'" 1 
ATOM   5104  C  "C2'" . DA    E 2 1   ? -0.987  82.582  -60.278 1.00 151.83 ? 202  DA    F "C2'" 1 
ATOM   5105  C  "C1'" . DA    E 2 1   ? -1.638  83.912  -59.901 1.00 149.26 ? 202  DA    F "C1'" 1 
ATOM   5106  N  N9    . DA    E 2 1   ? -0.784  84.755  -59.053 1.00 141.51 ? 202  DA    F N9    1 
ATOM   5107  C  C8    . DA    E 2 1   ? 0.510   85.113  -59.357 1.00 128.71 ? 202  DA    F C8    1 
ATOM   5108  N  N7    . DA    E 2 1   ? 1.086   85.838  -58.430 1.00 121.54 ? 202  DA    F N7    1 
ATOM   5109  C  C5    . DA    E 2 1   ? 0.117   85.975  -57.444 1.00 123.07 ? 202  DA    F C5    1 
ATOM   5110  C  C6    . DA    E 2 1   ? 0.116   86.640  -56.199 1.00 108.38 ? 202  DA    F C6    1 
ATOM   5111  N  N6    . DA    E 2 1   ? 1.155   87.315  -55.720 1.00 99.47  ? 202  DA    F N6    1 
ATOM   5112  N  N1    . DA    E 2 1   ? -1.012  86.579  -55.450 1.00 114.64 ? 202  DA    F N1    1 
ATOM   5113  C  C2    . DA    E 2 1   ? -2.058  85.892  -55.931 1.00 126.02 ? 202  DA    F C2    1 
ATOM   5114  N  N3    . DA    E 2 1   ? -2.174  85.231  -57.083 1.00 135.43 ? 202  DA    F N3    1 
ATOM   5115  C  C4    . DA    E 2 1   ? -1.041  85.309  -57.810 1.00 138.71 ? 202  DA    F C4    1 
ATOM   5116  P  P     . DA    E 2 2   ? -0.686  79.236  -58.418 1.00 167.88 ? 203  DA    F P     1 
ATOM   5117  O  OP1   . DA    E 2 2   ? -0.594  77.848  -59.001 1.00 150.37 ? 203  DA    F OP1   1 
ATOM   5118  O  OP2   . DA    E 2 2   ? -1.414  79.349  -57.104 1.00 154.45 ? 203  DA    F OP2   1 
ATOM   5119  O  "O5'" . DA    E 2 2   ? 0.846   79.708  -58.239 1.00 146.82 ? 203  DA    F "O5'" 1 
ATOM   5120  C  "C5'" . DA    E 2 2   ? 1.618   80.163  -59.390 1.00 111.33 ? 203  DA    F "C5'" 1 
ATOM   5121  C  "C4'" . DA    E 2 2   ? 2.720   81.089  -58.932 1.00 86.60  ? 203  DA    F "C4'" 1 
ATOM   5122  O  "O4'" . DA    E 2 2   ? 2.170   82.230  -58.226 1.00 82.59  ? 203  DA    F "O4'" 1 
ATOM   5123  C  "C3'" . DA    E 2 2   ? 3.727   80.451  -57.981 1.00 70.59  ? 203  DA    F "C3'" 1 
ATOM   5124  O  "O3'" . DA    E 2 2   ? 4.979   81.063  -58.188 1.00 55.50  ? 203  DA    F "O3'" 1 
ATOM   5125  C  "C2'" . DA    E 2 2   ? 3.198   80.865  -56.616 1.00 72.29  ? 203  DA    F "C2'" 1 
ATOM   5126  C  "C1'" . DA    E 2 2   ? 2.684   82.275  -56.892 1.00 74.91  ? 203  DA    F "C1'" 1 
ATOM   5127  N  N9    . DA    E 2 2   ? 1.638   82.696  -55.945 1.00 75.29  ? 203  DA    F N9    1 
ATOM   5128  C  C8    . DA    E 2 2   ? 0.335   82.265  -55.962 1.00 71.71  ? 203  DA    F C8    1 
ATOM   5129  N  N7    . DA    E 2 2   ? -0.390  82.727  -54.978 1.00 71.09  ? 203  DA    F N7    1 
ATOM   5130  C  C5    . DA    E 2 2   ? 0.486   83.502  -54.240 1.00 73.72  ? 203  DA    F C5    1 
ATOM   5131  C  C6    . DA    E 2 2   ? 0.308   84.256  -53.059 1.00 84.19  ? 203  DA    F C6    1 
ATOM   5132  N  N6    . DA    E 2 2   ? -0.859  84.347  -52.419 1.00 77.14  ? 203  DA    F N6    1 
ATOM   5133  N  N1    . DA    E 2 2   ? 1.394   84.908  -52.560 1.00 79.25  ? 203  DA    F N1    1 
ATOM   5134  C  C2    . DA    E 2 2   ? 2.560   84.792  -53.216 1.00 75.82  ? 203  DA    F C2    1 
ATOM   5135  N  N3    . DA    E 2 2   ? 2.841   84.106  -54.327 1.00 75.82  ? 203  DA    F N3    1 
ATOM   5136  C  C4    . DA    E 2 2   ? 1.749   83.477  -54.808 1.00 75.96  ? 203  DA    F C4    1 
ATOM   5137  P  P     . DC    E 2 3   ? 6.216   80.160  -58.646 1.00 50.17  ? 204  DC    F P     1 
ATOM   5138  O  OP1   . DC    E 2 3   ? 7.151   81.080  -59.382 1.00 47.26  ? 204  DC    F OP1   1 
ATOM   5139  O  OP2   . DC    E 2 3   ? 5.731   78.812  -59.116 1.00 42.48  ? 204  DC    F OP2   1 
ATOM   5140  O  "O5'" . DC    E 2 3   ? 6.946   79.948  -57.238 1.00 45.76  ? 204  DC    F "O5'" 1 
ATOM   5141  C  "C5'" . DC    E 2 3   ? 7.768   81.003  -56.737 1.00 39.92  ? 204  DC    F "C5'" 1 
ATOM   5142  C  "C4'" . DC    E 2 3   ? 8.476   80.489  -55.515 1.00 38.14  ? 204  DC    F "C4'" 1 
ATOM   5143  O  "O4'" . DC    E 2 3   ? 9.715   79.872  -55.913 1.00 36.27  ? 204  DC    F "O4'" 1 
ATOM   5144  C  "C3'" . DC    E 2 3   ? 8.845   81.561  -54.495 1.00 34.98  ? 204  DC    F "C3'" 1 
ATOM   5145  O  "O3'" . DC    E 2 3   ? 7.737   81.703  -53.604 1.00 33.84  ? 204  DC    F "O3'" 1 
ATOM   5146  C  "C2'" . DC    E 2 3   ? 10.068  80.942  -53.841 1.00 32.53  ? 204  DC    F "C2'" 1 
ATOM   5147  C  "C1'" . DC    E 2 3   ? 10.745  80.266  -55.017 1.00 35.69  ? 204  DC    F "C1'" 1 
ATOM   5148  N  N1    . DC    E 2 3   ? 11.679  81.121  -55.783 1.00 36.18  ? 204  DC    F N1    1 
ATOM   5149  C  C2    . DC    E 2 3   ? 12.943  81.395  -55.257 1.00 34.64  ? 204  DC    F C2    1 
ATOM   5150  O  O2    . DC    E 2 3   ? 13.235  80.960  -54.136 1.00 35.07  ? 204  DC    F O2    1 
ATOM   5151  N  N3    . DC    E 2 3   ? 13.794  82.172  -55.977 1.00 36.78  ? 204  DC    F N3    1 
ATOM   5152  C  C4    . DC    E 2 3   ? 13.442  82.635  -57.188 1.00 37.54  ? 204  DC    F C4    1 
ATOM   5153  N  N4    . DC    E 2 3   ? 14.317  83.377  -57.856 1.00 36.98  ? 204  DC    F N4    1 
ATOM   5154  C  C5    . DC    E 2 3   ? 12.162  82.363  -57.737 1.00 34.35  ? 204  DC    F C5    1 
ATOM   5155  C  C6    . DC    E 2 3   ? 11.325  81.604  -57.015 1.00 35.17  ? 204  DC    F C6    1 
ATOM   5156  P  P     . DG    E 2 4   ? 7.399   83.180  -53.083 1.00 31.44  ? 205  DG    F P     1 
ATOM   5157  O  OP1   . DG    E 2 4   ? 6.147   82.982  -52.268 1.00 32.85  ? 205  DG    F OP1   1 
ATOM   5158  O  OP2   . DG    E 2 4   ? 7.473   84.110  -54.252 1.00 35.00  ? 205  DG    F OP2   1 
ATOM   5159  O  "O5'" . DG    E 2 4   ? 8.650   83.539  -52.153 1.00 29.66  ? 205  DG    F "O5'" 1 
ATOM   5160  C  "C5'" . DG    E 2 4   ? 8.677   82.970  -50.824 1.00 33.01  ? 205  DG    F "C5'" 1 
ATOM   5161  C  "C4'" . DG    E 2 4   ? 9.961   83.379  -50.160 1.00 31.80  ? 205  DG    F "C4'" 1 
ATOM   5162  O  "O4'" . DG    E 2 4   ? 11.056  83.018  -51.021 1.00 31.08  ? 205  DG    F "O4'" 1 
ATOM   5163  C  "C3'" . DG    E 2 4   ? 10.093  84.889  -49.968 1.00 33.16  ? 205  DG    F "C3'" 1 
ATOM   5164  O  "O3'" . DG    E 2 4   ? 9.484   85.267  -48.743 1.00 31.59  ? 205  DG    F "O3'" 1 
ATOM   5165  C  "C2'" . DG    E 2 4   ? 11.608  85.067  -49.918 1.00 34.58  ? 205  DG    F "C2'" 1 
ATOM   5166  C  "C1'" . DG    E 2 4   ? 12.094  83.991  -50.879 1.00 32.88  ? 205  DG    F "C1'" 1 
ATOM   5167  N  N9    . DG    E 2 4   ? 12.436  84.474  -52.213 1.00 31.82  ? 205  DG    F N9    1 
ATOM   5168  C  C8    . DG    E 2 4   ? 11.757  84.362  -53.402 1.00 32.27  ? 205  DG    F C8    1 
ATOM   5169  N  N7    . DG    E 2 4   ? 12.408  84.869  -54.421 1.00 30.34  ? 205  DG    F N7    1 
ATOM   5170  C  C5    . DG    E 2 4   ? 13.596  85.338  -53.877 1.00 29.71  ? 205  DG    F C5    1 
ATOM   5171  C  C6    . DG    E 2 4   ? 14.693  86.002  -54.489 1.00 32.11  ? 205  DG    F C6    1 
ATOM   5172  O  O6    . DG    E 2 4   ? 14.874  86.285  -55.685 1.00 36.92  ? 205  DG    F O6    1 
ATOM   5173  N  N1    . DG    E 2 4   ? 15.670  86.325  -53.546 1.00 33.14  ? 205  DG    F N1    1 
ATOM   5174  C  C2    . DG    E 2 4   ? 15.604  86.046  -52.197 1.00 32.71  ? 205  DG    F C2    1 
ATOM   5175  N  N2    . DG    E 2 4   ? 16.646  86.407  -51.443 1.00 29.41  ? 205  DG    F N2    1 
ATOM   5176  N  N3    . DG    E 2 4   ? 14.581  85.429  -51.620 1.00 34.86  ? 205  DG    F N3    1 
ATOM   5177  C  C4    . DG    E 2 4   ? 13.619  85.103  -52.517 1.00 32.07  ? 205  DG    F C4    1 
ATOM   5178  P  P     . DG    E 2 5   ? 9.034   86.806  -48.679 1.00 31.26  ? 206  DG    F P     1 
ATOM   5179  O  OP1   . DG    E 2 5   ? 8.469   86.995  -47.301 1.00 33.03  ? 206  DG    F OP1   1 
ATOM   5180  O  OP2   . DG    E 2 5   ? 8.236   87.111  -49.916 1.00 34.23  ? 206  DG    F OP2   1 
ATOM   5181  O  "O5'" . DG    E 2 5   ? 10.432  87.568  -48.744 1.00 30.10  ? 206  DG    F "O5'" 1 
ATOM   5182  C  "C5'" . DG    E 2 5   ? 11.202  87.665  -47.529 1.00 32.95  ? 206  DG    F "C5'" 1 
ATOM   5183  C  "C4'" . DG    E 2 5   ? 12.465  88.433  -47.827 1.00 34.89  ? 206  DG    F "C4'" 1 
ATOM   5184  O  "O4'" . DG    E 2 5   ? 13.149  87.886  -48.974 1.00 33.43  ? 206  DG    F "O4'" 1 
ATOM   5185  C  "C3'" . DG    E 2 5   ? 12.252  89.895  -48.190 1.00 34.81  ? 206  DG    F "C3'" 1 
ATOM   5186  O  "O3'" . DG    E 2 5   ? 12.026  90.626  -46.992 1.00 38.17  ? 206  DG    F "O3'" 1 
ATOM   5187  C  "C2'" . DG    E 2 5   ? 13.606  90.216  -48.816 1.00 37.59  ? 206  DG    F "C2'" 1 
ATOM   5188  C  "C1'" . DG    E 2 5   ? 13.925  88.931  -49.574 1.00 34.86  ? 206  DG    F "C1'" 1 
ATOM   5189  N  N9    . DG    E 2 5   ? 13.640  88.964  -51.015 1.00 31.43  ? 206  DG    F N9    1 
ATOM   5190  C  C8    . DG    E 2 5   ? 12.565  88.502  -51.739 1.00 31.47  ? 206  DG    F C8    1 
ATOM   5191  N  N7    . DG    E 2 5   ? 12.695  88.688  -53.034 1.00 31.24  ? 206  DG    F N7    1 
ATOM   5192  C  C5    . DG    E 2 5   ? 13.949  89.284  -53.180 1.00 27.80  ? 206  DG    F C5    1 
ATOM   5193  C  C6    . DG    E 2 5   ? 14.648  89.702  -54.344 1.00 26.00  ? 206  DG    F C6    1 
ATOM   5194  O  O6    . DG    E 2 5   ? 14.346  89.586  -55.547 1.00 28.68  ? 206  DG    F O6    1 
ATOM   5195  N  N1    . DG    E 2 5   ? 15.851  90.297  -54.005 1.00 25.90  ? 206  DG    F N1    1 
ATOM   5196  C  C2    . DG    E 2 5   ? 16.367  90.428  -52.738 1.00 28.72  ? 206  DG    F C2    1 
ATOM   5197  N  N2    . DG    E 2 5   ? 17.573  91.007  -52.625 1.00 29.40  ? 206  DG    F N2    1 
ATOM   5198  N  N3    . DG    E 2 5   ? 15.730  90.025  -51.645 1.00 30.57  ? 206  DG    F N3    1 
ATOM   5199  C  C4    . DG    E 2 5   ? 14.526  89.471  -51.940 1.00 30.37  ? 206  DG    F C4    1 
ATOM   5200  P  P     . DC    E 2 6   ? 11.361  92.059  -47.235 1.00 33.12  ? 207  DC    F P     1 
ATOM   5201  O  OP1   . DC    E 2 6   ? 10.875  92.525  -45.902 1.00 32.44  ? 207  DC    F OP1   1 
ATOM   5202  O  OP2   . DC    E 2 6   ? 10.496  92.020  -48.464 1.00 36.95  ? 207  DC    F OP2   1 
ATOM   5203  O  "O5'" . DC    E 2 6   ? 12.677  92.864  -47.644 1.00 36.96  ? 207  DC    F "O5'" 1 
ATOM   5204  C  "C5'" . DC    E 2 6   ? 12.532  94.117  -48.349 1.00 35.10  ? 207  DC    F "C5'" 1 
ATOM   5205  C  "C4'" . DC    E 2 6   ? 13.837  94.428  -49.037 1.00 32.75  ? 207  DC    F "C4'" 1 
ATOM   5206  O  "O4'" . DC    E 2 6   ? 14.099  93.446  -50.060 1.00 29.19  ? 207  DC    F "O4'" 1 
ATOM   5207  C  "C3'" . DC    E 2 6   ? 13.837  95.765  -49.745 1.00 31.13  ? 207  DC    F "C3'" 1 
ATOM   5208  O  "O3'" . DC    E 2 6   ? 14.317  96.696  -48.811 1.00 31.75  ? 207  DC    F "O3'" 1 
ATOM   5209  C  "C2'" . DC    E 2 6   ? 14.784  95.557  -50.919 1.00 30.17  ? 207  DC    F "C2'" 1 
ATOM   5210  C  "C1'" . DC    E 2 6   ? 14.762  94.053  -51.147 1.00 29.67  ? 207  DC    F "C1'" 1 
ATOM   5211  N  N1    . DC    E 2 6   ? 14.073  93.614  -52.367 1.00 27.24  ? 207  DC    F N1    1 
ATOM   5212  C  C2    . DC    E 2 6   ? 14.704  93.810  -53.588 1.00 28.14  ? 207  DC    F C2    1 
ATOM   5213  O  O2    . DC    E 2 6   ? 15.782  94.429  -53.599 1.00 28.18  ? 207  DC    F O2    1 
ATOM   5214  N  N3    . DC    E 2 6   ? 14.096  93.364  -54.712 1.00 26.92  ? 207  DC    F N3    1 
ATOM   5215  C  C4    . DC    E 2 6   ? 12.916  92.732  -54.642 1.00 28.28  ? 207  DC    F C4    1 
ATOM   5216  N  N4    . DC    E 2 6   ? 12.369  92.314  -55.773 1.00 30.18  ? 207  DC    F N4    1 
ATOM   5217  C  C5    . DC    E 2 6   ? 12.265  92.505  -53.404 1.00 27.06  ? 207  DC    F C5    1 
ATOM   5218  C  C6    . DC    E 2 6   ? 12.889  92.938  -52.298 1.00 31.48  ? 207  DC    F C6    1 
ATOM   5219  P  P     . DG    E 2 7   ? 13.650  98.142  -48.992 1.00 29.63  ? 208  DG    F P     1 
ATOM   5220  O  OP1   . DG    E 2 7   ? 14.317  98.955  -47.923 1.00 29.76  ? 208  DG    F OP1   1 
ATOM   5221  O  OP2   . DG    E 2 7   ? 12.159  98.030  -49.100 1.00 31.11  ? 208  DG    F OP2   1 
ATOM   5222  O  "O5'" . DG    E 2 7   ? 14.235  98.546  -50.428 1.00 31.40  ? 208  DG    F "O5'" 1 
ATOM   5223  C  "C5'" . DG    E 2 7   ? 15.626  98.978  -50.479 1.00 31.68  ? 208  DG    F "C5'" 1 
ATOM   5224  C  "C4'" . DG    E 2 7   ? 15.919  99.486  -51.863 1.00 30.95  ? 208  DG    F "C4'" 1 
ATOM   5225  O  "O4'" . DG    E 2 7   ? 15.483  98.482  -52.794 1.00 29.67  ? 208  DG    F "O4'" 1 
ATOM   5226  C  "C3'" . DG    E 2 7   ? 15.211  100.796 -52.248 1.00 31.41  ? 208  DG    F "C3'" 1 
ATOM   5227  O  "O3'" . DG    E 2 7   ? 16.129  101.616 -52.985 1.00 34.46  ? 208  DG    F "O3'" 1 
ATOM   5228  C  "C2'" . DG    E 2 7   ? 14.040  100.307 -53.096 1.00 28.99  ? 208  DG    F "C2'" 1 
ATOM   5229  C  "C1'" . DG    E 2 7   ? 14.645  99.088  -53.776 1.00 30.16  ? 208  DG    F "C1'" 1 
ATOM   5230  N  N9    . DG    E 2 7   ? 13.665  98.095  -54.212 1.00 27.86  ? 208  DG    F N9    1 
ATOM   5231  C  C8    . DG    E 2 7   ? 12.680  97.559  -53.421 1.00 29.07  ? 208  DG    F C8    1 
ATOM   5232  N  N7    . DG    E 2 7   ? 11.912  96.706  -54.057 1.00 29.72  ? 208  DG    F N7    1 
ATOM   5233  C  C5    . DG    E 2 7   ? 12.422  96.686  -55.350 1.00 26.32  ? 208  DG    F C5    1 
ATOM   5234  C  C6    . DG    E 2 7   ? 11.997  95.954  -56.479 1.00 28.86  ? 208  DG    F C6    1 
ATOM   5235  O  O6    . DG    E 2 7   ? 11.062  95.142  -56.572 1.00 30.93  ? 208  DG    F O6    1 
ATOM   5236  N  N1    . DG    E 2 7   ? 12.790  96.228  -57.591 1.00 28.68  ? 208  DG    F N1    1 
ATOM   5237  C  C2    . DG    E 2 7   ? 13.854  97.088  -57.613 1.00 27.91  ? 208  DG    F C2    1 
ATOM   5238  N  N2    . DG    E 2 7   ? 14.479  97.218  -58.791 1.00 32.13  ? 208  DG    F N2    1 
ATOM   5239  N  N3    . DG    E 2 7   ? 14.265  97.779  -56.558 1.00 28.22  ? 208  DG    F N3    1 
ATOM   5240  C  C4    . DG    E 2 7   ? 13.506  97.531  -55.461 1.00 27.59  ? 208  DG    F C4    1 
ATOM   5241  P  P     . DC    E 2 8   ? 15.773  103.120 -53.434 1.00 31.79  ? 209  DC    F P     1 
ATOM   5242  O  OP1   . DC    E 2 8   ? 16.984  103.994 -53.251 1.00 35.99  ? 209  DC    F OP1   1 
ATOM   5243  O  OP2   . DC    E 2 8   ? 14.480  103.572 -52.806 1.00 36.29  ? 209  DC    F OP2   1 
ATOM   5244  O  "O5'" . DC    E 2 8   ? 15.436  102.776 -54.963 1.00 32.52  ? 209  DC    F "O5'" 1 
ATOM   5245  C  "C5'" . DC    E 2 8   ? 16.530  102.401 -55.824 1.00 37.21  ? 209  DC    F "C5'" 1 
ATOM   5246  C  "C4'" . DC    E 2 8   ? 16.129  102.542 -57.272 1.00 34.66  ? 209  DC    F "C4'" 1 
ATOM   5247  O  "O4'" . DC    E 2 8   ? 15.251  101.462 -57.670 1.00 37.22  ? 209  DC    F "O4'" 1 
ATOM   5248  C  "C3'" . DC    E 2 8   ? 15.403  103.839 -57.622 1.00 34.25  ? 209  DC    F "C3'" 1 
ATOM   5249  O  "O3'" . DC    E 2 8   ? 15.847  104.247 -58.917 1.00 37.63  ? 209  DC    F "O3'" 1 
ATOM   5250  C  "C2'" . DC    E 2 8   ? 13.954  103.388 -57.665 1.00 35.94  ? 209  DC    F "C2'" 1 
ATOM   5251  C  "C1'" . DC    E 2 8   ? 14.084  101.998 -58.265 1.00 36.05  ? 209  DC    F "C1'" 1 
ATOM   5252  N  N1    . DC    E 2 8   ? 12.962  101.074 -57.968 1.00 33.94  ? 209  DC    F N1    1 
ATOM   5253  C  C2    . DC    E 2 8   ? 12.496  100.232 -58.982 1.00 34.17  ? 209  DC    F C2    1 
ATOM   5254  O  O2    . DC    E 2 8   ? 12.999  100.293 -60.118 1.00 34.39  ? 209  DC    F O2    1 
ATOM   5255  N  N3    . DC    E 2 8   ? 11.495  99.369  -58.700 1.00 31.74  ? 209  DC    F N3    1 
ATOM   5256  C  C4    . DC    E 2 8   ? 10.958  99.319  -57.477 1.00 33.38  ? 209  DC    F C4    1 
ATOM   5257  N  N4    . DC    E 2 8   ? 9.985   98.442  -57.287 1.00 34.96  ? 209  DC    F N4    1 
ATOM   5258  C  C5    . DC    E 2 8   ? 11.422  100.156 -56.423 1.00 33.76  ? 209  DC    F C5    1 
ATOM   5259  C  C6    . DC    E 2 8   ? 12.427  101.005 -56.709 1.00 34.19  ? 209  DC    F C6    1 
ATOM   5260  P  P     . DC    E 2 9   ? 15.493  105.724 -59.468 1.00 34.84  ? 210  DC    F P     1 
ATOM   5261  O  OP1   . DC    E 2 9   ? 16.801  106.240 -59.992 1.00 38.73  ? 210  DC    F OP1   1 
ATOM   5262  O  OP2   . DC    E 2 9   ? 14.685  106.534 -58.489 1.00 33.47  ? 210  DC    F OP2   1 
ATOM   5263  O  "O5'" . DC    E 2 9   ? 14.609  105.288 -60.730 1.00 30.74  ? 210  DC    F "O5'" 1 
ATOM   5264  C  "C5'" . DC    E 2 9   ? 15.326  104.617 -61.794 1.00 36.92  ? 210  DC    F "C5'" 1 
ATOM   5265  C  "C4'" . DC    E 2 9   ? 14.356  104.204 -62.868 1.00 42.29  ? 210  DC    F "C4'" 1 
ATOM   5266  O  "O4'" . DC    E 2 9   ? 13.519  103.127 -62.401 1.00 41.97  ? 210  DC    F "O4'" 1 
ATOM   5267  C  "C3'" . DC    E 2 9   ? 13.438  105.341 -63.293 1.00 45.66  ? 210  DC    F "C3'" 1 
ATOM   5268  O  "O3'" . DC    E 2 9   ? 13.734  105.714 -64.638 1.00 51.71  ? 210  DC    F "O3'" 1 
ATOM   5269  C  "C2'" . DC    E 2 9   ? 12.034  104.761 -63.226 1.00 50.26  ? 210  DC    F "C2'" 1 
ATOM   5270  C  "C1'" . DC    E 2 9   ? 12.205  103.289 -62.883 1.00 44.77  ? 210  DC    F "C1'" 1 
ATOM   5271  N  N1    . DC    E 2 9   ? 11.280  102.849 -61.809 1.00 40.08  ? 210  DC    F N1    1 
ATOM   5272  C  C2    . DC    E 2 9   ? 10.260  101.941 -62.102 1.00 38.71  ? 210  DC    F C2    1 
ATOM   5273  O  O2    . DC    E 2 9   ? 10.184  101.480 -63.251 1.00 38.15  ? 210  DC    F O2    1 
ATOM   5274  N  N3    . DC    E 2 9   ? 9.430   101.539 -61.111 1.00 36.46  ? 210  DC    F N3    1 
ATOM   5275  C  C4    . DC    E 2 9   ? 9.545   102.059 -59.885 1.00 38.25  ? 210  DC    F C4    1 
ATOM   5276  N  N4    . DC    E 2 9   ? 8.714   101.625 -58.942 1.00 40.07  ? 210  DC    F N4    1 
ATOM   5277  C  C5    . DC    E 2 9   ? 10.549  103.017 -59.583 1.00 39.54  ? 210  DC    F C5    1 
ATOM   5278  C  C6    . DC    E 2 9   ? 11.386  103.379 -60.565 1.00 38.98  ? 210  DC    F C6    1 
ATOM   5279  P  P     . DG    E 2 10  ? 13.040  107.082 -65.146 1.00 45.02  ? 211  DG    F P     1 
ATOM   5280  O  OP1   . DG    E 2 10  ? 14.012  107.622 -66.165 1.00 59.53  ? 211  DG    F OP1   1 
ATOM   5281  O  OP2   . DG    E 2 10  ? 12.484  107.916 -64.009 1.00 37.88  ? 211  DG    F OP2   1 
ATOM   5282  O  "O5'" . DG    E 2 10  ? 11.782  106.509 -65.968 1.00 39.36  ? 211  DG    F "O5'" 1 
ATOM   5283  C  "C5'" . DG    E 2 10  ? 12.022  105.583 -67.057 1.00 41.11  ? 211  DG    F "C5'" 1 
ATOM   5284  C  "C4'" . DG    E 2 10  ? 10.695  105.070 -67.549 1.00 41.47  ? 211  DG    F "C4'" 1 
ATOM   5285  O  "O4'" . DG    E 2 10  ? 10.017  104.352 -66.490 1.00 43.93  ? 211  DG    F "O4'" 1 
ATOM   5286  C  "C3'" . DG    E 2 10  ? 9.727   106.160 -68.013 1.00 42.63  ? 211  DG    F "C3'" 1 
ATOM   5287  O  "O3'" . DG    E 2 10  ? 9.039   105.615 -69.143 1.00 46.24  ? 211  DG    F "O3'" 1 
ATOM   5288  C  "C2'" . DG    E 2 10  ? 8.830   106.358 -66.794 1.00 41.97  ? 211  DG    F "C2'" 1 
ATOM   5289  C  "C1'" . DG    E 2 10  ? 8.756   104.951 -66.205 1.00 41.10  ? 211  DG    F "C1'" 1 
ATOM   5290  N  N9    . DG    E 2 10  ? 8.521   104.916 -64.756 1.00 37.62  ? 211  DG    F N9    1 
ATOM   5291  C  C8    . DG    E 2 10  ? 9.117   105.673 -63.774 1.00 38.72  ? 211  DG    F C8    1 
ATOM   5292  N  N7    . DG    E 2 10  ? 8.670   105.427 -62.564 1.00 34.89  ? 211  DG    F N7    1 
ATOM   5293  C  C5    . DG    E 2 10  ? 7.719   104.436 -62.755 1.00 34.91  ? 211  DG    F C5    1 
ATOM   5294  C  C6    . DG    E 2 10  ? 6.904   103.768 -61.796 1.00 35.93  ? 211  DG    F C6    1 
ATOM   5295  O  O6    . DG    E 2 10  ? 6.880   103.915 -60.554 1.00 33.09  ? 211  DG    F O6    1 
ATOM   5296  N  N1    . DG    E 2 10  ? 6.066   102.841 -62.422 1.00 33.49  ? 211  DG    F N1    1 
ATOM   5297  C  C2    . DG    E 2 10  ? 6.018   102.592 -63.778 1.00 35.55  ? 211  DG    F C2    1 
ATOM   5298  N  N2    . DG    E 2 10  ? 5.129   101.675 -64.174 1.00 32.48  ? 211  DG    F N2    1 
ATOM   5299  N  N3    . DG    E 2 10  ? 6.804   103.194 -64.683 1.00 37.71  ? 211  DG    F N3    1 
ATOM   5300  C  C4    . DG    E 2 10  ? 7.602   104.126 -64.101 1.00 38.03  ? 211  DG    F C4    1 
ATOM   5301  P  P     . DT    E 2 11  ? 7.921   106.529 -69.840 1.00 41.56  ? 212  DT    F P     1 
ATOM   5302  O  OP1   . DT    E 2 11  ? 8.056   106.210 -71.303 1.00 38.74  ? 212  DT    F OP1   1 
ATOM   5303  O  OP2   . DT    E 2 11  ? 7.977   107.927 -69.278 1.00 41.82  ? 212  DT    F OP2   1 
ATOM   5304  O  "O5'" . DT    E 2 11  ? 6.604   105.785 -69.281 1.00 38.36  ? 212  DT    F "O5'" 1 
ATOM   5305  C  "C5'" . DT    E 2 11  ? 6.359   104.439 -69.783 1.00 45.79  ? 212  DT    F "C5'" 1 
ATOM   5306  C  "C4'" . DT    E 2 11  ? 5.027   103.943 -69.282 1.00 45.43  ? 212  DT    F "C4'" 1 
ATOM   5307  O  "O4'" . DT    E 2 11  ? 5.021   103.967 -67.840 1.00 43.38  ? 212  DT    F "O4'" 1 
ATOM   5308  C  "C3'" . DT    E 2 11  ? 3.843   104.792 -69.738 1.00 45.31  ? 212  DT    F "C3'" 1 
ATOM   5309  O  "O3'" . DT    E 2 11  ? 2.907   103.912 -70.327 1.00 54.00  ? 212  DT    F "O3'" 1 
ATOM   5310  C  "C2'" . DT    E 2 11  ? 3.320   105.430 -68.459 1.00 45.08  ? 212  DT    F "C2'" 1 
ATOM   5311  C  "C1'" . DT    E 2 11  ? 3.759   104.439 -67.400 1.00 42.58  ? 212  DT    F "C1'" 1 
ATOM   5312  N  N1    . DT    E 2 11  ? 3.967   104.993 -66.049 1.00 42.38  ? 212  DT    F N1    1 
ATOM   5313  C  C2    . DT    E 2 11  ? 3.252   104.439 -65.006 1.00 43.60  ? 212  DT    F C2    1 
ATOM   5314  O  O2    . DT    E 2 11  ? 2.435   103.541 -65.165 1.00 43.13  ? 212  DT    F O2    1 
ATOM   5315  N  N3    . DT    E 2 11  ? 3.496   105.002 -63.778 1.00 41.49  ? 212  DT    F N3    1 
ATOM   5316  C  C4    . DT    E 2 11  ? 4.388   106.023 -63.484 1.00 42.63  ? 212  DT    F C4    1 
ATOM   5317  O  O4    . DT    E 2 11  ? 4.531   106.418 -62.312 1.00 41.11  ? 212  DT    F O4    1 
ATOM   5318  C  C5    . DT    E 2 11  ? 5.087   106.571 -64.625 1.00 41.78  ? 212  DT    F C5    1 
ATOM   5319  C  C7    . DT    E 2 11  ? 6.052   107.698 -64.387 1.00 42.04  ? 212  DT    F C7    1 
ATOM   5320  C  C6    . DT    E 2 11  ? 4.860   106.027 -65.835 1.00 41.78  ? 212  DT    F C6    1 
ATOM   5321  P  P     . DG    E 2 12  ? 1.790   104.542 -71.307 1.00 45.72  ? 213  DG    F P     1 
ATOM   5322  O  OP1   . DG    E 2 12  ? 1.551   103.446 -72.306 1.00 42.70  ? 213  DG    F OP1   1 
ATOM   5323  O  OP2   . DG    E 2 12  ? 2.117   105.940 -71.736 1.00 47.12  ? 213  DG    F OP2   1 
ATOM   5324  O  "O5'" . DG    E 2 12  ? 0.580   104.708 -70.252 1.00 44.91  ? 213  DG    F "O5'" 1 
ATOM   5325  C  "C5'" . DG    E 2 12  ? -0.165  103.534 -69.808 1.00 44.40  ? 213  DG    F "C5'" 1 
ATOM   5326  C  "C4'" . DG    E 2 12  ? -1.230  103.942 -68.814 1.00 43.86  ? 213  DG    F "C4'" 1 
ATOM   5327  O  "O4'" . DG    E 2 12  ? -0.582  104.524 -67.665 1.00 39.57  ? 213  DG    F "O4'" 1 
ATOM   5328  C  "C3'" . DG    E 2 12  ? -2.245  104.996 -69.298 1.00 51.70  ? 213  DG    F "C3'" 1 
ATOM   5329  O  "O3'" . DG    E 2 12  ? -3.529  104.870 -68.667 1.00 55.38  ? 213  DG    F "O3'" 1 
ATOM   5330  C  "C2'" . DG    E 2 12  ? -1.619  106.296 -68.807 1.00 45.98  ? 213  DG    F "C2'" 1 
ATOM   5331  C  "C1'" . DG    E 2 12  ? -1.132  105.826 -67.447 1.00 47.36  ? 213  DG    F "C1'" 1 
ATOM   5332  N  N9    . DG    E 2 12  ? -0.116  106.673 -66.838 1.00 47.60  ? 213  DG    F N9    1 
ATOM   5333  C  C8    . DG    E 2 12  ? 0.784   107.559 -67.383 1.00 48.47  ? 213  DG    F C8    1 
ATOM   5334  N  N7    . DG    E 2 12  ? 1.536   108.147 -66.482 1.00 49.92  ? 213  DG    F N7    1 
ATOM   5335  C  C5    . DG    E 2 12  ? 1.097   107.611 -65.277 1.00 46.11  ? 213  DG    F C5    1 
ATOM   5336  C  C6    . DG    E 2 12  ? 1.560   107.830 -63.963 1.00 42.05  ? 213  DG    F C6    1 
ATOM   5337  O  O6    . DG    E 2 12  ? 2.453   108.597 -63.589 1.00 43.41  ? 213  DG    F O6    1 
ATOM   5338  N  N1    . DG    E 2 12  ? 0.833   107.084 -63.037 1.00 42.21  ? 213  DG    F N1    1 
ATOM   5339  C  C2    . DG    E 2 12  ? -0.174  106.196 -63.333 1.00 44.79  ? 213  DG    F C2    1 
ATOM   5340  N  N2    . DG    E 2 12  ? -0.745  105.557 -62.303 1.00 46.03  ? 213  DG    F N2    1 
ATOM   5341  N  N3    . DG    E 2 12  ? -0.590  105.952 -64.572 1.00 50.46  ? 213  DG    F N3    1 
ATOM   5342  C  C4    . DG    E 2 12  ? 0.083   106.700 -65.483 1.00 49.44  ? 213  DG    F C4    1 
ATOM   5343  P  P     . DG    E 2 13  ? -4.709  104.392 -69.647 1.00 60.87  ? 214  DG    F P     1 
ATOM   5344  O  OP1   . DG    E 2 13  ? -4.348  103.114 -70.362 1.00 54.24  ? 214  DG    F OP1   1 
ATOM   5345  O  OP2   . DG    E 2 13  ? -5.127  105.601 -70.447 1.00 56.32  ? 214  DG    F OP2   1 
ATOM   5346  O  "O5'" . DG    E 2 13  ? -5.804  104.063 -68.517 1.00 65.37  ? 214  DG    F "O5'" 1 
ATOM   5347  C  "C5'" . DG    E 2 13  ? -5.522  103.012 -67.545 1.00 68.40  ? 214  DG    F "C5'" 1 
ATOM   5348  C  "C4'" . DG    E 2 13  ? -6.035  103.416 -66.182 1.00 65.12  ? 214  DG    F "C4'" 1 
ATOM   5349  O  "O4'" . DG    E 2 13  ? -5.081  104.267 -65.506 1.00 58.50  ? 214  DG    F "O4'" 1 
ATOM   5350  C  "C3'" . DG    E 2 13  ? -7.355  104.180 -66.190 1.00 69.04  ? 214  DG    F "C3'" 1 
ATOM   5351  O  "O3'" . DG    E 2 13  ? -8.105  103.693 -65.073 1.00 75.80  ? 214  DG    F "O3'" 1 
ATOM   5352  C  "C2'" . DG    E 2 13  ? -6.907  105.634 -66.042 1.00 63.29  ? 214  DG    F "C2'" 1 
ATOM   5353  C  "C1'" . DG    E 2 13  ? -5.706  105.490 -65.120 1.00 60.08  ? 214  DG    F "C1'" 1 
ATOM   5354  N  N9    . DG    E 2 13  ? -4.699  106.541 -65.233 1.00 60.49  ? 214  DG    F N9    1 
ATOM   5355  C  C8    . DG    E 2 13  ? -4.231  107.054 -66.420 1.00 59.48  ? 214  DG    F C8    1 
ATOM   5356  N  N7    . DG    E 2 13  ? -3.298  107.961 -66.260 1.00 62.71  ? 214  DG    F N7    1 
ATOM   5357  C  C5    . DG    E 2 13  ? -3.140  108.055 -64.882 1.00 58.49  ? 214  DG    F C5    1 
ATOM   5358  C  C6    . DG    E 2 13  ? -2.269  108.877 -64.125 1.00 54.02  ? 214  DG    F C6    1 
ATOM   5359  O  O6    . DG    E 2 13  ? -1.448  109.705 -64.536 1.00 58.54  ? 214  DG    F O6    1 
ATOM   5360  N  N1    . DG    E 2 13  ? -2.421  108.661 -62.754 1.00 55.80  ? 214  DG    F N1    1 
ATOM   5361  C  C2    . DG    E 2 13  ? -3.313  107.778 -62.188 1.00 57.17  ? 214  DG    F C2    1 
ATOM   5362  N  N2    . DG    E 2 13  ? -3.315  107.725 -60.850 1.00 55.70  ? 214  DG    F N2    1 
ATOM   5363  N  N3    . DG    E 2 13  ? -4.132  106.993 -62.895 1.00 52.74  ? 214  DG    F N3    1 
ATOM   5364  C  C4    . DG    E 2 13  ? -3.988  107.174 -64.233 1.00 58.40  ? 214  DG    F C4    1 
ATOM   5365  P  P     . DT    E 2 14  ? -9.629  104.193 -64.956 1.00 77.36  ? 215  DT    F P     1 
ATOM   5366  O  OP1   . DT    E 2 14  ? -10.386 103.025 -64.391 1.00 80.58  ? 215  DT    F OP1   1 
ATOM   5367  O  OP2   . DT    E 2 14  ? -10.072 104.816 -66.256 1.00 75.98  ? 215  DT    F OP2   1 
ATOM   5368  O  "O5'" . DT    E 2 14  ? -9.462  105.316 -63.818 1.00 70.83  ? 215  DT    F "O5'" 1 
ATOM   5369  C  "C5'" . DT    E 2 14  ? -8.967  104.869 -62.537 1.00 76.03  ? 215  DT    F "C5'" 1 
ATOM   5370  C  "C4'" . DT    E 2 14  ? -8.856  106.030 -61.583 1.00 80.05  ? 215  DT    F "C4'" 1 
ATOM   5371  O  "O4'" . DT    E 2 14  ? -7.740  106.869 -61.951 1.00 76.97  ? 215  DT    F "O4'" 1 
ATOM   5372  C  "C3'" . DT    E 2 14  ? -10.081 106.943 -61.517 1.00 88.18  ? 215  DT    F "C3'" 1 
ATOM   5373  O  "O3'" . DT    E 2 14  ? -10.387 107.143 -60.137 1.00 99.92  ? 215  DT    F "O3'" 1 
ATOM   5374  C  "C2'" . DT    E 2 14  ? -9.613  108.237 -62.169 1.00 80.31  ? 215  DT    F "C2'" 1 
ATOM   5375  C  "C1'" . DT    E 2 14  ? -8.132  108.227 -61.819 1.00 77.45  ? 215  DT    F "C1'" 1 
ATOM   5376  N  N1    . DT    E 2 14  ? -7.262  109.008 -62.717 1.00 71.92  ? 215  DT    F N1    1 
ATOM   5377  C  C2    . DT    E 2 14  ? -6.291  109.819 -62.160 1.00 66.33  ? 215  DT    F C2    1 
ATOM   5378  O  O2    . DT    E 2 14  ? -6.145  109.962 -60.948 1.00 61.25  ? 215  DT    F O2    1 
ATOM   5379  N  N3    . DT    E 2 14  ? -5.516  110.484 -63.079 1.00 63.94  ? 215  DT    F N3    1 
ATOM   5380  C  C4    . DT    E 2 14  ? -5.609  110.421 -64.460 1.00 65.53  ? 215  DT    F C4    1 
ATOM   5381  O  O4    . DT    E 2 14  ? -4.834  111.091 -65.150 1.00 65.64  ? 215  DT    F O4    1 
ATOM   5382  C  C5    . DT    E 2 14  ? -6.645  109.546 -64.974 1.00 72.81  ? 215  DT    F C5    1 
ATOM   5383  C  C7    . DT    E 2 14  ? -6.824  109.398 -66.461 1.00 71.68  ? 215  DT    F C7    1 
ATOM   5384  C  C6    . DT    E 2 14  ? -7.405  108.887 -64.087 1.00 71.86  ? 215  DT    F C6    1 
ATOM   5385  P  P     . DC    E 2 15  ? -11.894 107.567 -59.763 1.00 100.03 ? 216  DC    F P     1 
ATOM   5386  O  OP1   . DC    E 2 15  ? -12.364 106.574 -58.734 1.00 93.85  ? 216  DC    F OP1   1 
ATOM   5387  O  OP2   . DC    E 2 15  ? -12.700 107.841 -61.012 1.00 79.44  ? 216  DC    F OP2   1 
ATOM   5388  O  "O5'" . DC    E 2 15  ? -11.585 108.952 -59.009 1.00 92.78  ? 216  DC    F "O5'" 1 
ATOM   5389  C  "C5'" . DC    E 2 15  ? -10.528 108.981 -58.009 1.00 100.35 ? 216  DC    F "C5'" 1 
ATOM   5390  C  "C4'" . DC    E 2 15  ? -10.096 110.414 -57.830 1.00 112.26 ? 216  DC    F "C4'" 1 
ATOM   5391  O  "O4'" . DC    E 2 15  ? -9.249  110.827 -58.933 1.00 106.86 ? 216  DC    F "O4'" 1 
ATOM   5392  C  "C3'" . DC    E 2 15  ? -11.268 111.396 -57.797 1.00 120.23 ? 216  DC    F "C3'" 1 
ATOM   5393  O  "O3'" . DC    E 2 15  ? -11.078 112.390 -56.791 1.00 140.22 ? 216  DC    F "O3'" 1 
ATOM   5394  C  "C2'" . DC    E 2 15  ? -11.214 112.026 -59.179 1.00 109.41 ? 216  DC    F "C2'" 1 
ATOM   5395  C  "C1'" . DC    E 2 15  ? -9.713  112.075 -59.403 1.00 99.87  ? 216  DC    F "C1'" 1 
ATOM   5396  N  N1    . DC    E 2 15  ? -9.282  112.268 -60.810 1.00 86.14  ? 216  DC    F N1    1 
ATOM   5397  C  C2    . DC    E 2 15  ? -8.099  112.976 -61.049 1.00 76.71  ? 216  DC    F C2    1 
ATOM   5398  O  O2    . DC    E 2 15  ? -7.449  113.398 -60.079 1.00 70.59  ? 216  DC    F O2    1 
ATOM   5399  N  N3    . DC    E 2 15  ? -7.704  113.175 -62.333 1.00 73.78  ? 216  DC    F N3    1 
ATOM   5400  C  C4    . DC    E 2 15  ? -8.443  112.710 -63.354 1.00 75.39  ? 216  DC    F C4    1 
ATOM   5401  N  N4    . DC    E 2 15  ? -8.015  112.941 -64.583 1.00 76.15  ? 216  DC    F N4    1 
ATOM   5402  C  C5    . DC    E 2 15  ? -9.653  111.998 -63.132 1.00 78.24  ? 216  DC    F C5    1 
ATOM   5403  C  C6    . DC    E 2 15  ? -10.033 111.808 -61.857 1.00 86.85  ? 216  DC    F C6    1 
HETATM 5404  P  P     . OMG   E 2 16  ? -12.478 112.717 -56.032 1.00 147.02 ? 217  OMG   F P     1 
HETATM 5405  O  OP1   . OMG   E 2 16  ? -12.741 111.634 -55.020 1.00 133.31 ? 217  OMG   F OP1   1 
HETATM 5406  O  OP2   . OMG   E 2 16  ? -13.533 112.984 -57.078 1.00 126.77 ? 217  OMG   F OP2   1 
HETATM 5407  O  "O5'" . OMG   E 2 16  ? -12.169 114.098 -55.258 1.00 143.70 ? 217  OMG   F "O5'" 1 
HETATM 5408  C  "C5'" . OMG   E 2 16  ? -10.809 114.440 -54.848 1.00 142.05 ? 217  OMG   F "C5'" 1 
HETATM 5409  C  "C4'" . OMG   E 2 16  ? -10.503 115.870 -55.235 1.00 139.07 ? 217  OMG   F "C4'" 1 
HETATM 5410  O  "O4'" . OMG   E 2 16  ? -10.106 115.924 -56.634 1.00 137.06 ? 217  OMG   F "O4'" 1 
HETATM 5411  C  "C3'" . OMG   E 2 16  ? -11.661 116.872 -55.102 1.00 134.46 ? 217  OMG   F "C3'" 1 
HETATM 5412  O  "O3'" . OMG   E 2 16  ? -11.147 118.118 -54.649 1.00 130.47 ? 217  OMG   F "O3'" 1 
HETATM 5413  C  "C2'" . OMG   E 2 16  ? -12.240 116.902 -56.528 1.00 133.92 ? 217  OMG   F "C2'" 1 
HETATM 5414  O  "O2'" . OMG   E 2 16  ? -12.996 118.076 -56.835 1.00 119.42 ? 217  OMG   F "O2'" 1 
HETATM 5415  C  CM2   . OMG   E 2 16  ? -14.294 117.811 -57.372 1.00 106.13 ? 217  OMG   F CM2   1 
HETATM 5416  C  "C1'" . OMG   E 2 16  ? -10.946 116.811 -57.341 1.00 130.24 ? 217  OMG   F "C1'" 1 
HETATM 5417  N  N9    . OMG   E 2 16  ? -11.125 116.310 -58.705 1.00 124.67 ? 217  OMG   F N9    1 
HETATM 5418  C  C8    . OMG   E 2 16  ? -12.141 115.521 -59.196 1.00 118.39 ? 217  OMG   F C8    1 
HETATM 5419  N  N7    . OMG   E 2 16  ? -12.018 115.242 -60.473 1.00 111.31 ? 217  OMG   F N7    1 
HETATM 5420  C  C5    . OMG   E 2 16  ? -10.849 115.888 -60.856 1.00 111.90 ? 217  OMG   F C5    1 
HETATM 5421  C  C6    . OMG   E 2 16  ? -10.207 115.951 -62.125 1.00 104.04 ? 217  OMG   F C6    1 
HETATM 5422  O  O6    . OMG   E 2 16  ? -10.549 115.433 -63.201 1.00 91.63  ? 217  OMG   F O6    1 
HETATM 5423  N  N1    . OMG   E 2 16  ? -9.044  116.723 -62.060 1.00 100.65 ? 217  OMG   F N1    1 
HETATM 5424  C  C2    . OMG   E 2 16  ? -8.561  117.354 -60.935 1.00 97.28  ? 217  OMG   F C2    1 
HETATM 5425  N  N2    . OMG   E 2 16  ? -7.429  118.060 -61.074 1.00 90.22  ? 217  OMG   F N2    1 
HETATM 5426  N  N3    . OMG   E 2 16  ? -9.160  117.295 -59.744 1.00 102.49 ? 217  OMG   F N3    1 
HETATM 5427  C  C4    . OMG   E 2 16  ? -10.293 116.550 -59.777 1.00 114.76 ? 217  OMG   F C4    1 
ATOM   5428  N  N     . GLU   F 3 2   ? 8.878   120.140 -16.322 1.00 107.68 ? 295  GLU   D N     1 
ATOM   5429  C  CA    . GLU   F 3 2   ? 8.990   120.000 -17.801 1.00 114.24 ? 295  GLU   D CA    1 
ATOM   5430  C  C     . GLU   F 3 2   ? 10.396  120.433 -18.237 1.00 125.70 ? 295  GLU   D C     1 
ATOM   5431  O  O     . GLU   F 3 2   ? 11.340  119.664 -18.061 1.00 129.54 ? 295  GLU   D O     1 
ATOM   5432  C  CB    . GLU   F 3 2   ? 7.850   120.769 -18.486 1.00 106.24 ? 295  GLU   D CB    1 
ATOM   5433  N  N     . GLU   F 3 3   ? 10.545  121.673 -18.749 1.00 128.49 ? 296  GLU   D N     1 
ATOM   5434  C  CA    . GLU   F 3 3   ? 11.697  122.076 -19.558 1.00 116.58 ? 296  GLU   D CA    1 
ATOM   5435  C  C     . GLU   F 3 3   ? 12.871  122.611 -18.732 1.00 106.84 ? 296  GLU   D C     1 
ATOM   5436  O  O     . GLU   F 3 3   ? 12.692  123.412 -17.818 1.00 109.94 ? 296  GLU   D O     1 
ATOM   5437  C  CB    . GLU   F 3 3   ? 11.311  123.166 -20.563 1.00 110.70 ? 296  GLU   D CB    1 
ATOM   5438  C  CG    . GLU   F 3 3   ? 10.823  122.623 -21.894 1.00 109.76 ? 296  GLU   D CG    1 
ATOM   5439  C  CD    . GLU   F 3 3   ? 10.868  123.635 -23.025 1.00 111.85 ? 296  GLU   D CD    1 
ATOM   5440  O  OE1   . GLU   F 3 3   ? 9.968   124.490 -23.081 1.00 101.90 ? 296  GLU   D OE1   1 
ATOM   5441  O  OE2   . GLU   F 3 3   ? 11.820  123.575 -23.837 1.00 107.67 ? 296  GLU   D OE2   1 
ATOM   5442  N  N     . ALA   F 3 4   ? 14.084  122.209 -19.138 1.00 96.91  ? 297  ALA   D N     1 
ATOM   5443  C  CA    . ALA   F 3 4   ? 15.331  122.647 -18.531 1.00 93.90  ? 297  ALA   D CA    1 
ATOM   5444  C  C     . ALA   F 3 4   ? 16.302  123.103 -19.625 1.00 95.03  ? 297  ALA   D C     1 
ATOM   5445  O  O     . ALA   F 3 4   ? 15.995  123.027 -20.817 1.00 77.01  ? 297  ALA   D O     1 
ATOM   5446  C  CB    . ALA   F 3 4   ? 15.909  121.530 -17.688 1.00 93.45  ? 297  ALA   D CB    1 
ATOM   5447  N  N     . PRO   F 3 5   ? 17.506  123.611 -19.264 1.00 100.75 ? 298  PRO   D N     1 
ATOM   5448  C  CA    . PRO   F 3 5   ? 18.436  124.168 -20.247 1.00 97.27  ? 298  PRO   D CA    1 
ATOM   5449  C  C     . PRO   F 3 5   ? 19.490  123.176 -20.745 1.00 90.20  ? 298  PRO   D C     1 
ATOM   5450  O  O     . PRO   F 3 5   ? 19.925  122.292 -20.000 1.00 86.53  ? 298  PRO   D O     1 
ATOM   5451  C  CB    . PRO   F 3 5   ? 19.067  125.301 -19.418 1.00 96.62  ? 298  PRO   D CB    1 
ATOM   5452  C  CG    . PRO   F 3 5   ? 19.160  124.729 -18.005 1.00 98.27  ? 298  PRO   D CG    1 
ATOM   5453  C  CD    . PRO   F 3 5   ? 18.031  123.720 -17.890 1.00 100.47 ? 298  PRO   D CD    1 
ATOM   5454  N  N     . TRP   F 3 6   ? 19.907  123.347 -22.009 1.00 78.39  ? 299  TRP   D N     1 
ATOM   5455  C  CA    . TRP   F 3 6   ? 21.048  122.618 -22.543 1.00 79.17  ? 299  TRP   D CA    1 
ATOM   5456  C  C     . TRP   F 3 6   ? 22.282  122.944 -21.697 1.00 75.16  ? 299  TRP   D C     1 
ATOM   5457  O  O     . TRP   F 3 6   ? 22.418  124.082 -21.264 1.00 79.11  ? 299  TRP   D O     1 
ATOM   5458  C  CB    . TRP   F 3 6   ? 21.266  122.969 -24.025 1.00 78.71  ? 299  TRP   D CB    1 
ATOM   5459  C  CG    . TRP   F 3 6   ? 22.055  121.923 -24.749 1.00 78.80  ? 299  TRP   D CG    1 
ATOM   5460  C  CD1   . TRP   F 3 6   ? 23.402  121.905 -24.966 1.00 77.48  ? 299  TRP   D CD1   1 
ATOM   5461  C  CD2   . TRP   F 3 6   ? 21.537  120.709 -25.323 1.00 75.42  ? 299  TRP   D CD2   1 
ATOM   5462  N  NE1   . TRP   F 3 6   ? 23.758  120.758 -25.626 1.00 80.12  ? 299  TRP   D NE1   1 
ATOM   5463  C  CE2   . TRP   F 3 6   ? 22.637  120.006 -25.859 1.00 72.76  ? 299  TRP   D CE2   1 
ATOM   5464  C  CE3   . TRP   F 3 6   ? 20.258  120.145 -25.433 1.00 75.16  ? 299  TRP   D CE3   1 
ATOM   5465  C  CZ2   . TRP   F 3 6   ? 22.490  118.777 -26.499 1.00 71.23  ? 299  TRP   D CZ2   1 
ATOM   5466  C  CZ3   . TRP   F 3 6   ? 20.113  118.933 -26.073 1.00 71.18  ? 299  TRP   D CZ3   1 
ATOM   5467  C  CH2   . TRP   F 3 6   ? 21.216  118.265 -26.604 1.00 69.33  ? 299  TRP   D CH2   1 
ATOM   5468  N  N     . PRO   F 3 7   ? 23.232  122.013 -21.423 1.00 81.01  ? 300  PRO   D N     1 
ATOM   5469  C  CA    . PRO   F 3 7   ? 23.193  120.634 -21.906 1.00 79.74  ? 300  PRO   D CA    1 
ATOM   5470  C  C     . PRO   F 3 7   ? 22.381  119.713 -21.000 1.00 78.60  ? 300  PRO   D C     1 
ATOM   5471  O  O     . PRO   F 3 7   ? 22.103  120.050 -19.850 1.00 74.86  ? 300  PRO   D O     1 
ATOM   5472  C  CB    . PRO   F 3 7   ? 24.682  120.232 -21.915 1.00 76.86  ? 300  PRO   D CB    1 
ATOM   5473  C  CG    . PRO   F 3 7   ? 25.284  121.000 -20.760 1.00 78.05  ? 300  PRO   D CG    1 
ATOM   5474  C  CD    . PRO   F 3 7   ? 24.447  122.263 -20.627 1.00 81.93  ? 300  PRO   D CD    1 
ATOM   5475  N  N     . PRO   F 3 8   ? 21.973  118.527 -21.513 1.00 79.08  ? 301  PRO   D N     1 
ATOM   5476  C  CA    . PRO   F 3 8   ? 21.289  117.517 -20.706 1.00 72.04  ? 301  PRO   D CA    1 
ATOM   5477  C  C     . PRO   F 3 8   ? 22.230  116.728 -19.801 1.00 65.80  ? 301  PRO   D C     1 
ATOM   5478  O  O     . PRO   F 3 8   ? 23.437  116.700 -20.035 1.00 68.94  ? 301  PRO   D O     1 
ATOM   5479  C  CB    . PRO   F 3 8   ? 20.701  116.583 -21.775 1.00 76.93  ? 301  PRO   D CB    1 
ATOM   5480  C  CG    . PRO   F 3 8   ? 21.714  116.648 -22.901 1.00 75.78  ? 301  PRO   D CG    1 
ATOM   5481  C  CD    . PRO   F 3 8   ? 22.143  118.100 -22.915 1.00 75.65  ? 301  PRO   D CD    1 
ATOM   5482  N  N     . PRO   F 3 9   ? 21.702  116.029 -18.769 1.00 66.75  ? 302  PRO   D N     1 
ATOM   5483  C  CA    . PRO   F 3 9   ? 22.530  115.168 -17.922 1.00 66.22  ? 302  PRO   D CA    1 
ATOM   5484  C  C     . PRO   F 3 9   ? 22.966  113.950 -18.733 1.00 68.36  ? 302  PRO   D C     1 
ATOM   5485  O  O     . PRO   F 3 9   ? 22.530  113.791 -19.869 1.00 62.08  ? 302  PRO   D O     1 
ATOM   5486  C  CB    . PRO   F 3 9   ? 21.593  114.792 -16.760 1.00 67.36  ? 302  PRO   D CB    1 
ATOM   5487  C  CG    . PRO   F 3 9   ? 20.179  114.919 -17.337 1.00 62.80  ? 302  PRO   D CG    1 
ATOM   5488  C  CD    . PRO   F 3 9   ? 20.272  115.985 -18.406 1.00 64.75  ? 302  PRO   D CD    1 
ATOM   5489  N  N     . GLU   F 3 10  ? 23.791  113.079 -18.140 1.00 72.46  ? 303  GLU   D N     1 
ATOM   5490  C  CA    . GLU   F 3 10  ? 24.299  111.914 -18.849 1.00 69.36  ? 303  GLU   D CA    1 
ATOM   5491  C  C     . GLU   F 3 10  ? 23.230  110.824 -18.959 1.00 67.87  ? 303  GLU   D C     1 
ATOM   5492  O  O     . GLU   F 3 10  ? 22.313  110.748 -18.137 1.00 61.87  ? 303  GLU   D O     1 
ATOM   5493  C  CB    . GLU   F 3 10  ? 25.584  111.414 -18.192 1.00 73.11  ? 303  GLU   D CB    1 
ATOM   5494  C  CG    . GLU   F 3 10  ? 26.727  112.402 -18.363 1.00 80.27  ? 303  GLU   D CG    1 
ATOM   5495  C  CD    . GLU   F 3 10  ? 27.916  111.851 -19.135 1.00 89.34  ? 303  GLU   D CD    1 
ATOM   5496  O  OE1   . GLU   F 3 10  ? 28.514  110.859 -18.673 1.00 91.10  ? 303  GLU   D OE1   1 
ATOM   5497  O  OE2   . GLU   F 3 10  ? 28.225  112.399 -20.216 1.00 93.13  ? 303  GLU   D OE2   1 
ATOM   5498  N  N     . GLY   F 3 11  ? 23.354  110.007 -20.020 1.00 62.42  ? 304  GLY   D N     1 
ATOM   5499  C  CA    . GLY   F 3 11  ? 22.406  108.948 -20.332 1.00 61.23  ? 304  GLY   D CA    1 
ATOM   5500  C  C     . GLY   F 3 11  ? 21.042  109.474 -20.794 1.00 60.83  ? 304  GLY   D C     1 
ATOM   5501  O  O     . GLY   F 3 11  ? 20.026  108.790 -20.666 1.00 59.18  ? 304  GLY   D O     1 
ATOM   5502  N  N     . ALA   F 3 12  ? 21.011  110.706 -21.311 1.00 54.75  ? 305  ALA   D N     1 
ATOM   5503  C  CA    . ALA   F 3 12  ? 19.784  111.260 -21.850 1.00 53.99  ? 305  ALA   D CA    1 
ATOM   5504  C  C     . ALA   F 3 12  ? 19.555  110.682 -23.244 1.00 56.19  ? 305  ALA   D C     1 
ATOM   5505  O  O     . ALA   F 3 12  ? 20.506  110.294 -23.922 1.00 58.99  ? 305  ALA   D O     1 
ATOM   5506  C  CB    . ALA   F 3 12  ? 19.872  112.765 -21.895 1.00 51.69  ? 305  ALA   D CB    1 
ATOM   5507  N  N     . PHE   F 3 13  ? 18.287  110.671 -23.662 1.00 48.50  ? 306  PHE   D N     1 
ATOM   5508  C  CA    . PHE   F 3 13  ? 17.892  110.230 -24.981 1.00 46.80  ? 306  PHE   D CA    1 
ATOM   5509  C  C     . PHE   F 3 13  ? 17.719  111.448 -25.877 1.00 48.23  ? 306  PHE   D C     1 
ATOM   5510  O  O     . PHE   F 3 13  ? 17.141  112.437 -25.457 1.00 52.19  ? 306  PHE   D O     1 
ATOM   5511  C  CB    . PHE   F 3 13  ? 16.576  109.446 -24.928 1.00 44.96  ? 306  PHE   D CB    1 
ATOM   5512  C  CG    . PHE   F 3 13  ? 16.648  108.108 -24.239 1.00 45.06  ? 306  PHE   D CG    1 
ATOM   5513  C  CD1   . PHE   F 3 13  ? 16.620  108.014 -22.853 1.00 48.41  ? 306  PHE   D CD1   1 
ATOM   5514  C  CD2   . PHE   F 3 13  ? 16.731  106.939 -24.982 1.00 46.88  ? 306  PHE   D CD2   1 
ATOM   5515  C  CE1   . PHE   F 3 13  ? 16.673  106.780 -22.222 1.00 47.66  ? 306  PHE   D CE1   1 
ATOM   5516  C  CE2   . PHE   F 3 13  ? 16.794  105.705 -24.350 1.00 49.40  ? 306  PHE   D CE2   1 
ATOM   5517  C  CZ    . PHE   F 3 13  ? 16.751  105.627 -22.973 1.00 50.00  ? 306  PHE   D CZ    1 
ATOM   5518  N  N     . VAL   F 3 14  ? 18.164  111.331 -27.128 1.00 49.25  ? 307  VAL   D N     1 
ATOM   5519  C  CA    . VAL   F 3 14  ? 18.187  112.445 -28.055 1.00 47.52  ? 307  VAL   D CA    1 
ATOM   5520  C  C     . VAL   F 3 14  ? 16.987  112.351 -28.991 1.00 44.39  ? 307  VAL   D C     1 
ATOM   5521  O  O     . VAL   F 3 14  ? 16.459  111.274 -29.274 1.00 52.48  ? 307  VAL   D O     1 
ATOM   5522  C  CB    . VAL   F 3 14  ? 19.501  112.486 -28.861 1.00 51.96  ? 307  VAL   D CB    1 
ATOM   5523  C  CG1   . VAL   F 3 14  ? 19.600  111.360 -29.879 1.00 50.46  ? 307  VAL   D CG1   1 
ATOM   5524  C  CG2   . VAL   F 3 14  ? 19.671  113.819 -29.571 1.00 55.69  ? 307  VAL   D CG2   1 
ATOM   5525  N  N     . GLY   F 3 15  ? 16.578  113.517 -29.485 1.00 40.55  ? 308  GLY   D N     1 
ATOM   5526  C  CA    . GLY   F 3 15  ? 15.650  113.622 -30.591 1.00 38.20  ? 308  GLY   D CA    1 
ATOM   5527  C  C     . GLY   F 3 15  ? 16.154  114.700 -31.534 1.00 42.25  ? 308  GLY   D C     1 
ATOM   5528  O  O     . GLY   F 3 15  ? 16.887  115.601 -31.113 1.00 46.84  ? 308  GLY   D O     1 
ATOM   5529  N  N     . PHE   F 3 16  ? 15.763  114.619 -32.806 1.00 41.58  ? 309  PHE   D N     1 
ATOM   5530  C  CA    . PHE   F 3 16  ? 16.320  115.544 -33.774 1.00 39.91  ? 309  PHE   D CA    1 
ATOM   5531  C  C     . PHE   F 3 16  ? 15.413  115.582 -34.990 1.00 41.75  ? 309  PHE   D C     1 
ATOM   5532  O  O     . PHE   F 3 16  ? 14.572  114.690 -35.158 1.00 42.11  ? 309  PHE   D O     1 
ATOM   5533  C  CB    . PHE   F 3 16  ? 17.757  115.148 -34.124 1.00 39.87  ? 309  PHE   D CB    1 
ATOM   5534  C  CG    . PHE   F 3 16  ? 17.882  113.768 -34.725 1.00 41.16  ? 309  PHE   D CG    1 
ATOM   5535  C  CD1   . PHE   F 3 16  ? 17.975  112.647 -33.917 1.00 39.99  ? 309  PHE   D CD1   1 
ATOM   5536  C  CD2   . PHE   F 3 16  ? 17.861  113.591 -36.099 1.00 42.59  ? 309  PHE   D CD2   1 
ATOM   5537  C  CE1   . PHE   F 3 16  ? 18.064  111.380 -34.474 1.00 41.79  ? 309  PHE   D CE1   1 
ATOM   5538  C  CE2   . PHE   F 3 16  ? 17.950  112.325 -36.654 1.00 43.80  ? 309  PHE   D CE2   1 
ATOM   5539  C  CZ    . PHE   F 3 16  ? 18.049  111.222 -35.840 1.00 41.07  ? 309  PHE   D CZ    1 
ATOM   5540  N  N     . VAL   F 3 17  ? 15.565  116.665 -35.780 1.00 40.86  ? 310  VAL   D N     1 
ATOM   5541  C  CA    . VAL   F 3 17  ? 14.850  116.811 -37.034 1.00 41.36  ? 310  VAL   D CA    1 
ATOM   5542  C  C     . VAL   F 3 17  ? 15.858  117.138 -38.129 1.00 42.12  ? 310  VAL   D C     1 
ATOM   5543  O  O     . VAL   F 3 17  ? 16.745  117.951 -37.914 1.00 41.90  ? 310  VAL   D O     1 
ATOM   5544  C  CB    . VAL   F 3 17  ? 13.730  117.865 -36.943 1.00 42.99  ? 310  VAL   D CB    1 
ATOM   5545  C  CG1   . VAL   F 3 17  ? 12.879  117.888 -38.204 1.00 47.11  ? 310  VAL   D CG1   1 
ATOM   5546  C  CG2   . VAL   F 3 17  ? 12.845  117.636 -35.725 1.00 48.44  ? 310  VAL   D CG2   1 
ATOM   5547  N  N     . LEU   F 3 18  ? 15.692  116.481 -39.286 1.00 43.84  ? 311  LEU   D N     1 
ATOM   5548  C  CA    . LEU   F 3 18  ? 16.513  116.675 -40.470 1.00 41.27  ? 311  LEU   D CA    1 
ATOM   5549  C  C     . LEU   F 3 18  ? 15.669  117.334 -41.558 1.00 42.20  ? 311  LEU   D C     1 
ATOM   5550  O  O     . LEU   F 3 18  ? 14.474  117.069 -41.636 1.00 41.35  ? 311  LEU   D O     1 
ATOM   5551  C  CB    . LEU   F 3 18  ? 16.957  115.300 -40.980 1.00 41.68  ? 311  LEU   D CB    1 
ATOM   5552  C  CG    . LEU   F 3 18  ? 17.834  114.459 -40.058 1.00 41.09  ? 311  LEU   D CG    1 
ATOM   5553  C  CD1   . LEU   F 3 18  ? 18.327  113.252 -40.832 1.00 37.79  ? 311  LEU   D CD1   1 
ATOM   5554  C  CD2   . LEU   F 3 18  ? 19.003  115.266 -39.486 1.00 38.99  ? 311  LEU   D CD2   1 
ATOM   5555  N  N     . SER   F 3 19  ? 16.297  118.132 -42.430 1.00 44.73  ? 312  SER   D N     1 
ATOM   5556  C  CA    . SER   F 3 19  ? 15.594  118.719 -43.563 1.00 45.64  ? 312  SER   D CA    1 
ATOM   5557  C  C     . SER   F 3 19  ? 15.086  117.631 -44.508 1.00 47.61  ? 312  SER   D C     1 
ATOM   5558  O  O     . SER   F 3 19  ? 14.166  117.888 -45.281 1.00 48.63  ? 312  SER   D O     1 
ATOM   5559  C  CB    . SER   F 3 19  ? 16.460  119.709 -44.305 1.00 47.33  ? 312  SER   D CB    1 
ATOM   5560  O  OG    . SER   F 3 19  ? 17.628  119.086 -44.838 1.00 46.11  ? 312  SER   D OG    1 
ATOM   5561  N  N     . ARG   F 3 20  ? 15.675  116.424 -44.435 1.00 48.70  ? 313  ARG   D N     1 
ATOM   5562  C  CA    . ARG   F 3 20  ? 15.340  115.333 -45.344 1.00 44.90  ? 313  ARG   D CA    1 
ATOM   5563  C  C     . ARG   F 3 20  ? 15.851  113.990 -44.801 1.00 43.25  ? 313  ARG   D C     1 
ATOM   5564  O  O     . ARG   F 3 20  ? 16.585  113.949 -43.822 1.00 40.99  ? 313  ARG   D O     1 
ATOM   5565  C  CB    . ARG   F 3 20  ? 15.922  115.646 -46.727 1.00 46.26  ? 313  ARG   D CB    1 
ATOM   5566  C  CG    . ARG   F 3 20  ? 17.392  116.045 -46.695 1.00 46.63  ? 313  ARG   D CG    1 
ATOM   5567  C  CD    . ARG   F 3 20  ? 17.939  116.498 -48.039 1.00 45.65  ? 313  ARG   D CD    1 
ATOM   5568  N  NE    . ARG   F 3 20  ? 17.997  115.435 -49.022 1.00 47.19  ? 313  ARG   D NE    1 
ATOM   5569  C  CZ    . ARG   F 3 20  ? 18.465  115.582 -50.250 1.00 48.66  ? 313  ARG   D CZ    1 
ATOM   5570  N  NH1   . ARG   F 3 20  ? 19.085  116.699 -50.580 1.00 50.55  ? 313  ARG   D NH1   1 
ATOM   5571  N  NH2   . ARG   F 3 20  ? 18.297  114.624 -51.145 1.00 46.73  ? 313  ARG   D NH2   1 
ATOM   5572  N  N     . LYS   F 3 21  ? 15.408  112.902 -45.453 1.00 45.20  ? 314  LYS   D N     1 
ATOM   5573  C  CA    . LYS   F 3 21  ? 15.689  111.506 -45.130 1.00 45.01  ? 314  LYS   D CA    1 
ATOM   5574  C  C     . LYS   F 3 21  ? 17.178  111.207 -44.951 1.00 43.79  ? 314  LYS   D C     1 
ATOM   5575  O  O     . LYS   F 3 21  ? 17.580  110.642 -43.932 1.00 44.23  ? 314  LYS   D O     1 
ATOM   5576  C  CB    . LYS   F 3 21  ? 15.298  110.626 -46.326 1.00 48.15  ? 314  LYS   D CB    1 
ATOM   5577  C  CG    . LYS   F 3 21  ? 13.858  110.145 -46.381 1.00 52.91  ? 314  LYS   D CG    1 
ATOM   5578  C  CD    . LYS   F 3 21  ? 13.363  109.775 -47.780 1.00 52.60  ? 314  LYS   D CD    1 
ATOM   5579  C  CE    . LYS   F 3 21  ? 14.366  109.088 -48.678 1.00 53.38  ? 314  LYS   D CE    1 
ATOM   5580  N  NZ    . LYS   F 3 21  ? 13.738  108.717 -49.972 1.00 54.98  ? 314  LYS   D NZ    1 
ATOM   5581  N  N     . GLU   F 3 22  ? 17.937  111.518 -46.013 1.00 37.84  ? 315  GLU   D N     1 
ATOM   5582  C  CA    . GLU   F 3 22  ? 19.309  111.102 -46.214 1.00 40.34  ? 315  GLU   D CA    1 
ATOM   5583  C  C     . GLU   F 3 22  ? 20.218  111.897 -45.293 1.00 40.29  ? 315  GLU   D C     1 
ATOM   5584  O  O     . GLU   F 3 22  ? 20.428  113.075 -45.537 1.00 41.33  ? 315  GLU   D O     1 
ATOM   5585  C  CB    . GLU   F 3 22  ? 19.768  111.375 -47.652 1.00 44.71  ? 315  GLU   D CB    1 
ATOM   5586  C  CG    . GLU   F 3 22  ? 18.851  110.804 -48.724 1.00 46.57  ? 315  GLU   D CG    1 
ATOM   5587  C  CD    . GLU   F 3 22  ? 17.805  111.769 -49.255 1.00 50.64  ? 315  GLU   D CD    1 
ATOM   5588  O  OE1   . GLU   F 3 22  ? 17.327  112.632 -48.477 1.00 50.77  ? 315  GLU   D OE1   1 
ATOM   5589  O  OE2   . GLU   F 3 22  ? 17.426  111.621 -50.429 1.00 57.31  ? 315  GLU   D OE2   1 
ATOM   5590  N  N     . PRO   F 3 23  ? 20.805  111.292 -44.235 1.00 45.34  ? 316  PRO   D N     1 
ATOM   5591  C  CA    . PRO   F 3 23  ? 21.629  112.036 -43.285 1.00 42.93  ? 316  PRO   D CA    1 
ATOM   5592  C  C     . PRO   F 3 23  ? 22.855  112.714 -43.888 1.00 42.36  ? 316  PRO   D C     1 
ATOM   5593  O  O     . PRO   F 3 23  ? 23.347  113.693 -43.327 1.00 41.10  ? 316  PRO   D O     1 
ATOM   5594  C  CB    . PRO   F 3 23  ? 22.112  110.988 -42.269 1.00 42.03  ? 316  PRO   D CB    1 
ATOM   5595  C  CG    . PRO   F 3 23  ? 21.136  109.848 -42.414 1.00 46.61  ? 316  PRO   D CG    1 
ATOM   5596  C  CD    . PRO   F 3 23  ? 20.671  109.874 -43.855 1.00 45.70  ? 316  PRO   D CD    1 
ATOM   5597  N  N     . MET   F 3 24  ? 23.360  112.196 -45.011 1.00 40.55  ? 317  MET   D N     1 
ATOM   5598  C  CA    . MET   F 3 24  ? 24.579  112.771 -45.566 1.00 43.61  ? 317  MET   D CA    1 
ATOM   5599  C  C     . MET   F 3 24  ? 24.258  114.082 -46.275 1.00 44.45  ? 317  MET   D C     1 
ATOM   5600  O  O     . MET   F 3 24  ? 25.130  114.933 -46.409 1.00 43.94  ? 317  MET   D O     1 
ATOM   5601  C  CB    . MET   F 3 24  ? 25.259  111.820 -46.556 1.00 42.58  ? 317  MET   D CB    1 
ATOM   5602  C  CG    . MET   F 3 24  ? 26.071  110.769 -45.865 1.00 42.28  ? 317  MET   D CG    1 
ATOM   5603  S  SD    . MET   F 3 24  ? 27.395  111.460 -44.850 1.00 35.32  ? 317  MET   D SD    1 
ATOM   5604  C  CE    . MET   F 3 24  ? 28.390  112.146 -46.175 1.00 36.36  ? 317  MET   D CE    1 
ATOM   5605  N  N     . TRP   F 3 25  ? 23.005  114.219 -46.727 1.00 42.55  ? 318  TRP   D N     1 
ATOM   5606  C  CA    . TRP   F 3 25  ? 22.565  115.385 -47.470 1.00 44.78  ? 318  TRP   D CA    1 
ATOM   5607  C  C     . TRP   F 3 25  ? 21.752  116.344 -46.608 1.00 46.12  ? 318  TRP   D C     1 
ATOM   5608  O  O     . TRP   F 3 25  ? 21.355  117.405 -47.064 1.00 52.93  ? 318  TRP   D O     1 
ATOM   5609  C  CB    . TRP   F 3 25  ? 21.750  114.926 -48.675 1.00 44.37  ? 318  TRP   D CB    1 
ATOM   5610  C  CG    . TRP   F 3 25  ? 22.585  114.259 -49.720 1.00 47.55  ? 318  TRP   D CG    1 
ATOM   5611  C  CD1   . TRP   F 3 25  ? 22.651  112.925 -49.992 1.00 47.20  ? 318  TRP   D CD1   1 
ATOM   5612  C  CD2   . TRP   F 3 25  ? 23.463  114.912 -50.657 1.00 49.69  ? 318  TRP   D CD2   1 
ATOM   5613  N  NE1   . TRP   F 3 25  ? 23.528  112.701 -51.017 1.00 51.83  ? 318  TRP   D NE1   1 
ATOM   5614  C  CE2   . TRP   F 3 25  ? 24.039  113.897 -51.452 1.00 52.11  ? 318  TRP   D CE2   1 
ATOM   5615  C  CE3   . TRP   F 3 25  ? 23.822  116.245 -50.895 1.00 48.74  ? 318  TRP   D CE3   1 
ATOM   5616  C  CZ2   . TRP   F 3 25  ? 24.937  114.178 -52.484 1.00 48.30  ? 318  TRP   D CZ2   1 
ATOM   5617  C  CZ3   . TRP   F 3 25  ? 24.713  116.521 -51.910 1.00 49.62  ? 318  TRP   D CZ3   1 
ATOM   5618  C  CH2   . TRP   F 3 25  ? 25.253  115.500 -52.696 1.00 48.05  ? 318  TRP   D CH2   1 
ATOM   5619  N  N     . ALA   F 3 26  ? 21.474  115.965 -45.368 1.00 49.99  ? 319  ALA   D N     1 
ATOM   5620  C  CA    . ALA   F 3 26  ? 20.434  116.648 -44.628 1.00 50.81  ? 319  ALA   D CA    1 
ATOM   5621  C  C     . ALA   F 3 26  ? 21.038  117.784 -43.823 1.00 47.91  ? 319  ALA   D C     1 
ATOM   5622  O  O     . ALA   F 3 26  ? 22.187  117.729 -43.389 1.00 46.68  ? 319  ALA   D O     1 
ATOM   5623  C  CB    . ALA   F 3 26  ? 19.702  115.696 -43.714 1.00 54.41  ? 319  ALA   D CB    1 
ATOM   5624  N  N     . ASP   F 3 27  ? 20.162  118.751 -43.561 1.00 49.32  ? 320  ASP   D N     1 
ATOM   5625  C  CA    . ASP   F 3 27  ? 20.399  119.831 -42.630 1.00 48.77  ? 320  ASP   D CA    1 
ATOM   5626  C  C     . ASP   F 3 27  ? 19.787  119.457 -41.280 1.00 46.61  ? 320  ASP   D C     1 
ATOM   5627  O  O     . ASP   F 3 27  ? 18.649  118.985 -41.221 1.00 48.58  ? 320  ASP   D O     1 
ATOM   5628  C  CB    . ASP   F 3 27  ? 19.781  121.090 -43.238 1.00 60.47  ? 320  ASP   D CB    1 
ATOM   5629  C  CG    . ASP   F 3 27  ? 20.438  122.380 -42.812 1.00 63.94  ? 320  ASP   D CG    1 
ATOM   5630  O  OD1   . ASP   F 3 27  ? 21.601  122.326 -42.372 1.00 76.51  ? 320  ASP   D OD1   1 
ATOM   5631  O  OD2   . ASP   F 3 27  ? 19.766  123.416 -42.916 1.00 69.33  ? 320  ASP   D OD2   1 
ATOM   5632  N  N     . LEU   F 3 28  ? 20.545  119.664 -40.199 1.00 42.90  ? 321  LEU   D N     1 
ATOM   5633  C  CA    . LEU   F 3 28  ? 20.052  119.460 -38.848 1.00 43.11  ? 321  LEU   D CA    1 
ATOM   5634  C  C     . LEU   F 3 28  ? 19.278  120.691 -38.365 1.00 47.44  ? 321  LEU   D C     1 
ATOM   5635  O  O     . LEU   F 3 28  ? 19.885  121.640 -37.874 1.00 48.06  ? 321  LEU   D O     1 
ATOM   5636  C  CB    . LEU   F 3 28  ? 21.256  119.191 -37.942 1.00 42.77  ? 321  LEU   D CB    1 
ATOM   5637  C  CG    . LEU   F 3 28  ? 20.921  118.924 -36.477 1.00 45.40  ? 321  LEU   D CG    1 
ATOM   5638  C  CD1   . LEU   F 3 28  ? 19.973  117.731 -36.338 1.00 44.42  ? 321  LEU   D CD1   1 
ATOM   5639  C  CD2   . LEU   F 3 28  ? 22.191  118.713 -35.664 1.00 46.16  ? 321  LEU   D CD2   1 
ATOM   5640  N  N     . LEU   F 3 29  ? 17.939  120.629 -38.450 1.00 47.80  ? 322  LEU   D N     1 
ATOM   5641  C  CA    . LEU   F 3 29  ? 17.045  121.711 -38.062 1.00 47.20  ? 322  LEU   D CA    1 
ATOM   5642  C  C     . LEU   F 3 29  ? 16.919  121.863 -36.543 1.00 48.36  ? 322  LEU   D C     1 
ATOM   5643  O  O     . LEU   F 3 29  ? 16.710  122.974 -36.066 1.00 46.90  ? 322  LEU   D O     1 
ATOM   5644  C  CB    . LEU   F 3 29  ? 15.658  121.447 -38.661 1.00 48.21  ? 322  LEU   D CB    1 
ATOM   5645  C  CG    . LEU   F 3 29  ? 15.573  121.386 -40.186 1.00 50.56  ? 322  LEU   D CG    1 
ATOM   5646  C  CD1   . LEU   F 3 29  ? 14.123  121.319 -40.645 1.00 49.25  ? 322  LEU   D CD1   1 
ATOM   5647  C  CD2   . LEU   F 3 29  ? 16.274  122.582 -40.823 1.00 53.65  ? 322  LEU   D CD2   1 
ATOM   5648  N  N     . ALA   F 3 30  ? 16.966  120.767 -35.774 1.00 51.33  ? 323  ALA   D N     1 
ATOM   5649  C  CA    . ALA   F 3 30  ? 16.674  120.836 -34.344 1.00 45.75  ? 323  ALA   D CA    1 
ATOM   5650  C  C     . ALA   F 3 30  ? 17.200  119.601 -33.616 1.00 46.36  ? 323  ALA   D C     1 
ATOM   5651  O  O     . ALA   F 3 30  ? 17.227  118.511 -34.188 1.00 49.13  ? 323  ALA   D O     1 
ATOM   5652  C  CB    . ALA   F 3 30  ? 15.186  120.987 -34.139 1.00 48.74  ? 323  ALA   D CB    1 
ATOM   5653  N  N     . LEU   F 3 31  ? 17.581  119.795 -32.346 1.00 43.31  ? 324  LEU   D N     1 
ATOM   5654  C  CA    . LEU   F 3 31  ? 18.115  118.751 -31.487 1.00 43.44  ? 324  LEU   D CA    1 
ATOM   5655  C  C     . LEU   F 3 31  ? 17.612  118.979 -30.067 1.00 49.60  ? 324  LEU   D C     1 
ATOM   5656  O  O     . LEU   F 3 31  ? 17.705  120.094 -29.560 1.00 52.01  ? 324  LEU   D O     1 
ATOM   5657  C  CB    . LEU   F 3 31  ? 19.646  118.797 -31.497 1.00 43.73  ? 324  LEU   D CB    1 
ATOM   5658  C  CG    . LEU   F 3 31  ? 20.353  117.712 -30.678 1.00 47.00  ? 324  LEU   D CG    1 
ATOM   5659  C  CD1   . LEU   F 3 31  ? 20.409  116.400 -31.433 1.00 48.23  ? 324  LEU   D CD1   1 
ATOM   5660  C  CD2   . LEU   F 3 31  ? 21.765  118.116 -30.286 1.00 49.07  ? 324  LEU   D CD2   1 
ATOM   5661  N  N     . ALA   F 3 32  ? 17.130  117.910 -29.416 1.00 53.57  ? 325  ALA   D N     1 
ATOM   5662  C  CA    . ALA   F 3 32  ? 16.772  117.964 -28.007 1.00 51.47  ? 325  ALA   D CA    1 
ATOM   5663  C  C     . ALA   F 3 32  ? 17.219  116.674 -27.347 1.00 52.12  ? 325  ALA   D C     1 
ATOM   5664  O  O     . ALA   F 3 32  ? 17.604  115.738 -28.039 1.00 57.55  ? 325  ALA   D O     1 
ATOM   5665  C  CB    . ALA   F 3 32  ? 15.288  118.171 -27.838 1.00 51.97  ? 325  ALA   D CB    1 
ATOM   5666  N  N     . ALA   F 3 33  ? 17.145  116.652 -26.014 1.00 53.44  ? 326  ALA   D N     1 
ATOM   5667  C  CA    . ALA   F 3 33  ? 17.468  115.477 -25.224 1.00 52.28  ? 326  ALA   D CA    1 
ATOM   5668  C  C     . ALA   F 3 33  ? 16.544  115.403 -24.006 1.00 57.16  ? 326  ALA   D C     1 
ATOM   5669  O  O     . ALA   F 3 33  ? 16.105  116.435 -23.497 1.00 59.51  ? 326  ALA   D O     1 
ATOM   5670  C  CB    . ALA   F 3 33  ? 18.920  115.522 -24.824 1.00 51.67  ? 326  ALA   D CB    1 
ATOM   5671  N  N     . ALA   F 3 34  ? 16.255  114.175 -23.542 1.00 53.88  ? 327  ALA   D N     1 
ATOM   5672  C  CA    . ALA   F 3 34  ? 15.295  113.958 -22.472 1.00 52.92  ? 327  ALA   D CA    1 
ATOM   5673  C  C     . ALA   F 3 34  ? 15.856  112.973 -21.455 1.00 56.27  ? 327  ALA   D C     1 
ATOM   5674  O  O     . ALA   F 3 34  ? 16.471  111.975 -21.819 1.00 65.29  ? 327  ALA   D O     1 
ATOM   5675  C  CB    . ALA   F 3 34  ? 13.985  113.470 -23.035 1.00 54.27  ? 327  ALA   D CB    1 
ATOM   5676  N  N     . ARG   F 3 35  ? 15.658  113.288 -20.172 1.00 56.29  ? 328  ARG   D N     1 
ATOM   5677  C  CA    . ARG   F 3 35  ? 15.934  112.358 -19.093 1.00 56.85  ? 328  ARG   D CA    1 
ATOM   5678  C  C     . ARG   F 3 35  ? 14.915  112.613 -17.984 1.00 60.96  ? 328  ARG   D C     1 
ATOM   5679  O  O     . ARG   F 3 35  ? 14.541  113.759 -17.736 1.00 65.60  ? 328  ARG   D O     1 
ATOM   5680  C  CB    . ARG   F 3 35  ? 17.369  112.503 -18.588 1.00 60.30  ? 328  ARG   D CB    1 
ATOM   5681  C  CG    . ARG   F 3 35  ? 17.941  111.225 -17.988 1.00 69.04  ? 328  ARG   D CG    1 
ATOM   5682  C  CD    . ARG   F 3 35  ? 18.724  111.456 -16.707 1.00 79.48  ? 328  ARG   D CD    1 
ATOM   5683  N  NE    . ARG   F 3 35  ? 19.735  110.421 -16.521 1.00 93.21  ? 328  ARG   D NE    1 
ATOM   5684  C  CZ    . ARG   F 3 35  ? 19.478  109.120 -16.472 1.00 96.29  ? 328  ARG   D CZ    1 
ATOM   5685  N  NH1   . ARG   F 3 35  ? 18.583  108.651 -15.619 1.00 94.01  ? 328  ARG   D NH1   1 
ATOM   5686  N  NH2   . ARG   F 3 35  ? 20.152  108.290 -17.250 1.00 99.11  ? 328  ARG   D NH2   1 
ATOM   5687  N  N     . GLY   F 3 36  ? 14.458  111.525 -17.350 1.00 61.15  ? 329  GLY   D N     1 
ATOM   5688  C  CA    . GLY   F 3 36  ? 13.407  111.559 -16.348 1.00 57.23  ? 329  GLY   D CA    1 
ATOM   5689  C  C     . GLY   F 3 36  ? 12.229  112.445 -16.746 1.00 58.57  ? 329  GLY   D C     1 
ATOM   5690  O  O     . GLY   F 3 36  ? 11.617  113.058 -15.885 1.00 63.35  ? 329  GLY   D O     1 
ATOM   5691  N  N     . GLY   F 3 37  ? 11.902  112.514 -18.040 1.00 54.15  ? 330  GLY   D N     1 
ATOM   5692  C  CA    . GLY   F 3 37  ? 10.721  113.241 -18.483 1.00 57.79  ? 330  GLY   D CA    1 
ATOM   5693  C  C     . GLY   F 3 37  ? 10.988  114.708 -18.823 1.00 62.53  ? 330  GLY   D C     1 
ATOM   5694  O  O     . GLY   F 3 37  ? 10.146  115.331 -19.471 1.00 59.80  ? 330  GLY   D O     1 
ATOM   5695  N  N     . ARG   F 3 38  ? 12.155  115.236 -18.398 1.00 65.76  ? 331  ARG   D N     1 
ATOM   5696  C  CA    . ARG   F 3 38  ? 12.567  116.609 -18.667 1.00 65.27  ? 331  ARG   D CA    1 
ATOM   5697  C  C     . ARG   F 3 38  ? 13.152  116.741 -20.076 1.00 63.42  ? 331  ARG   D C     1 
ATOM   5698  O  O     . ARG   F 3 38  ? 14.034  115.980 -20.465 1.00 61.98  ? 331  ARG   D O     1 
ATOM   5699  C  CB    . ARG   F 3 38  ? 13.654  117.062 -17.687 1.00 74.00  ? 331  ARG   D CB    1 
ATOM   5700  C  CG    . ARG   F 3 38  ? 13.193  117.314 -16.260 1.00 83.31  ? 331  ARG   D CG    1 
ATOM   5701  C  CD    . ARG   F 3 38  ? 14.369  117.701 -15.383 1.00 91.93  ? 331  ARG   D CD    1 
ATOM   5702  N  NE    . ARG   F 3 38  ? 13.900  118.468 -14.238 1.00 102.73 ? 331  ARG   D NE    1 
ATOM   5703  C  CZ    . ARG   F 3 38  ? 13.585  117.949 -13.055 1.00 108.04 ? 331  ARG   D CZ    1 
ATOM   5704  N  NH1   . ARG   F 3 38  ? 13.942  116.709 -12.756 1.00 104.78 ? 331  ARG   D NH1   1 
ATOM   5705  N  NH2   . ARG   F 3 38  ? 12.916  118.676 -12.172 1.00 104.86 ? 331  ARG   D NH2   1 
ATOM   5706  N  N     . VAL   F 3 39  ? 12.684  117.745 -20.822 1.00 60.34  ? 332  VAL   D N     1 
ATOM   5707  C  CA    . VAL   F 3 39  ? 13.133  117.971 -22.185 1.00 62.37  ? 332  VAL   D CA    1 
ATOM   5708  C  C     . VAL   F 3 39  ? 14.098  119.157 -22.193 1.00 66.74  ? 332  VAL   D C     1 
ATOM   5709  O  O     . VAL   F 3 39  ? 13.720  120.258 -21.792 1.00 65.74  ? 332  VAL   D O     1 
ATOM   5710  C  CB    . VAL   F 3 39  ? 11.928  118.212 -23.111 1.00 63.73  ? 332  VAL   D CB    1 
ATOM   5711  C  CG1   . VAL   F 3 39  ? 12.364  118.410 -24.553 1.00 70.78  ? 332  VAL   D CG1   1 
ATOM   5712  C  CG2   . VAL   F 3 39  ? 10.902  117.090 -23.003 1.00 66.52  ? 332  VAL   D CG2   1 
ATOM   5713  N  N     . HIS   F 3 40  ? 15.340  118.916 -22.645 1.00 65.00  ? 333  HIS   D N     1 
ATOM   5714  C  CA    . HIS   F 3 40  ? 16.353  119.954 -22.779 1.00 57.81  ? 333  HIS   D CA    1 
ATOM   5715  C  C     . HIS   F 3 40  ? 16.548  120.285 -24.256 1.00 56.87  ? 333  HIS   D C     1 
ATOM   5716  O  O     . HIS   F 3 40  ? 17.079  119.466 -25.002 1.00 62.58  ? 333  HIS   D O     1 
ATOM   5717  C  CB    . HIS   F 3 40  ? 17.674  119.496 -22.152 1.00 57.50  ? 333  HIS   D CB    1 
ATOM   5718  C  CG    . HIS   F 3 40  ? 17.584  118.929 -20.766 1.00 59.41  ? 333  HIS   D CG    1 
ATOM   5719  N  ND1   . HIS   F 3 40  ? 18.316  119.405 -19.705 1.00 62.80  ? 333  HIS   D ND1   1 
ATOM   5720  C  CD2   . HIS   F 3 40  ? 16.864  117.871 -20.297 1.00 62.50  ? 333  HIS   D CD2   1 
ATOM   5721  C  CE1   . HIS   F 3 40  ? 18.047  118.685 -18.619 1.00 61.51  ? 333  HIS   D CE1   1 
ATOM   5722  N  NE2   . HIS   F 3 40  ? 17.149  117.723 -18.964 1.00 66.56  ? 333  HIS   D NE2   1 
ATOM   5723  N  N     . ARG   F 3 41  ? 16.110  121.475 -24.685 1.00 55.37  ? 334  ARG   D N     1 
ATOM   5724  C  CA    . ARG   F 3 41  ? 16.226  121.870 -26.082 1.00 57.59  ? 334  ARG   D CA    1 
ATOM   5725  C  C     . ARG   F 3 41  ? 17.541  122.620 -26.292 1.00 60.87  ? 334  ARG   D C     1 
ATOM   5726  O  O     . ARG   F 3 41  ? 17.944  123.414 -25.448 1.00 67.91  ? 334  ARG   D O     1 
ATOM   5727  C  CB    . ARG   F 3 41  ? 15.009  122.701 -26.494 1.00 57.88  ? 334  ARG   D CB    1 
ATOM   5728  C  CG    . ARG   F 3 41  ? 13.706  121.913 -26.496 1.00 58.96  ? 334  ARG   D CG    1 
ATOM   5729  C  CD    . ARG   F 3 41  ? 12.539  122.727 -27.014 1.00 61.95  ? 334  ARG   D CD    1 
ATOM   5730  N  NE    . ARG   F 3 41  ? 11.403  121.929 -27.460 1.00 64.97  ? 334  ARG   D NE    1 
ATOM   5731  C  CZ    . ARG   F 3 41  ? 10.556  121.275 -26.667 1.00 67.19  ? 334  ARG   D CZ    1 
ATOM   5732  N  NH1   . ARG   F 3 41  ? 10.740  121.237 -25.358 1.00 59.06  ? 334  ARG   D NH1   1 
ATOM   5733  N  NH2   . ARG   F 3 41  ? 9.528   120.636 -27.201 1.00 66.11  ? 334  ARG   D NH2   1 
ATOM   5734  N  N     . ALA   F 3 42  ? 18.222  122.331 -27.411 1.00 65.04  ? 335  ALA   D N     1 
ATOM   5735  C  CA    . ALA   F 3 42  ? 19.506  122.937 -27.738 1.00 63.25  ? 335  ALA   D CA    1 
ATOM   5736  C  C     . ALA   F 3 42  ? 19.289  124.081 -28.725 1.00 64.15  ? 335  ALA   D C     1 
ATOM   5737  O  O     . ALA   F 3 42  ? 18.736  123.846 -29.796 1.00 57.48  ? 335  ALA   D O     1 
ATOM   5738  C  CB    . ALA   F 3 42  ? 20.430  121.904 -28.327 1.00 60.13  ? 335  ALA   D CB    1 
ATOM   5739  N  N     . PRO   F 3 43  ? 19.713  125.330 -28.404 1.00 65.86  ? 336  PRO   D N     1 
ATOM   5740  C  CA    . PRO   F 3 43  ? 19.519  126.480 -29.299 1.00 66.50  ? 336  PRO   D CA    1 
ATOM   5741  C  C     . PRO   F 3 43  ? 20.412  126.480 -30.544 1.00 61.59  ? 336  PRO   D C     1 
ATOM   5742  O  O     . PRO   F 3 43  ? 20.029  127.013 -31.583 1.00 53.24  ? 336  PRO   D O     1 
ATOM   5743  C  CB    . PRO   F 3 43  ? 19.862  127.685 -28.407 1.00 67.05  ? 336  PRO   D CB    1 
ATOM   5744  C  CG    . PRO   F 3 43  ? 20.869  127.130 -27.419 1.00 71.12  ? 336  PRO   D CG    1 
ATOM   5745  C  CD    . PRO   F 3 43  ? 20.415  125.703 -27.162 1.00 71.25  ? 336  PRO   D CD    1 
ATOM   5746  N  N     . GLU   F 3 44  ? 21.605  125.876 -30.439 1.00 62.91  ? 337  GLU   D N     1 
ATOM   5747  C  CA    . GLU   F 3 44  ? 22.469  125.692 -31.600 1.00 66.97  ? 337  GLU   D CA    1 
ATOM   5748  C  C     . GLU   F 3 44  ? 22.669  124.196 -31.871 1.00 58.53  ? 337  GLU   D C     1 
ATOM   5749  O  O     . GLU   F 3 44  ? 23.581  123.567 -31.324 1.00 55.58  ? 337  GLU   D O     1 
ATOM   5750  C  CB    . GLU   F 3 44  ? 23.789  126.427 -31.371 1.00 75.44  ? 337  GLU   D CB    1 
ATOM   5751  C  CG    . GLU   F 3 44  ? 23.627  127.933 -31.240 1.00 76.58  ? 337  GLU   D CG    1 
ATOM   5752  C  CD    . GLU   F 3 44  ? 24.916  128.641 -30.864 1.00 77.44  ? 337  GLU   D CD    1 
ATOM   5753  O  OE1   . GLU   F 3 44  ? 25.392  128.445 -29.720 1.00 72.94  ? 337  GLU   D OE1   1 
ATOM   5754  O  OE2   . GLU   F 3 44  ? 25.458  129.355 -31.729 1.00 79.34  ? 337  GLU   D OE2   1 
ATOM   5755  N  N     . PRO   F 3 45  ? 21.828  123.582 -32.738 1.00 53.48  ? 338  PRO   D N     1 
ATOM   5756  C  CA    . PRO   F 3 45  ? 21.809  122.120 -32.896 1.00 56.50  ? 338  PRO   D CA    1 
ATOM   5757  C  C     . PRO   F 3 45  ? 23.191  121.515 -33.169 1.00 52.66  ? 338  PRO   D C     1 
ATOM   5758  O  O     . PRO   F 3 45  ? 23.668  120.703 -32.377 1.00 50.01  ? 338  PRO   D O     1 
ATOM   5759  C  CB    . PRO   F 3 45  ? 20.855  121.858 -34.075 1.00 56.11  ? 338  PRO   D CB    1 
ATOM   5760  C  CG    . PRO   F 3 45  ? 20.060  123.156 -34.260 1.00 56.50  ? 338  PRO   D CG    1 
ATOM   5761  C  CD    . PRO   F 3 45  ? 20.882  124.264 -33.637 1.00 53.06  ? 338  PRO   D CD    1 
ATOM   5762  N  N     . TYR   F 3 46  ? 23.849  121.978 -34.246 1.00 51.75  ? 339  TYR   D N     1 
ATOM   5763  C  CA    . TYR   F 3 46  ? 25.127  121.443 -34.704 1.00 50.48  ? 339  TYR   D CA    1 
ATOM   5764  C  C     . TYR   F 3 46  ? 26.226  121.527 -33.644 1.00 51.16  ? 339  TYR   D C     1 
ATOM   5765  O  O     . TYR   F 3 46  ? 27.092  120.659 -33.595 1.00 51.29  ? 339  TYR   D O     1 
ATOM   5766  C  CB    . TYR   F 3 46  ? 25.603  122.174 -35.960 1.00 47.57  ? 339  TYR   D CB    1 
ATOM   5767  C  CG    . TYR   F 3 46  ? 24.955  121.787 -37.268 1.00 43.12  ? 339  TYR   D CG    1 
ATOM   5768  C  CD1   . TYR   F 3 46  ? 25.412  120.710 -38.014 1.00 44.03  ? 339  TYR   D CD1   1 
ATOM   5769  C  CD2   . TYR   F 3 46  ? 23.918  122.530 -37.799 1.00 42.58  ? 339  TYR   D CD2   1 
ATOM   5770  C  CE1   . TYR   F 3 46  ? 24.851  120.384 -39.241 1.00 42.07  ? 339  TYR   D CE1   1 
ATOM   5771  C  CE2   . TYR   F 3 46  ? 23.336  122.209 -39.020 1.00 40.48  ? 339  TYR   D CE2   1 
ATOM   5772  C  CZ    . TYR   F 3 46  ? 23.807  121.136 -39.747 1.00 40.73  ? 339  TYR   D CZ    1 
ATOM   5773  O  OH    . TYR   F 3 46  ? 23.238  120.831 -40.964 1.00 43.71  ? 339  TYR   D OH    1 
ATOM   5774  N  N     . LYS   F 3 47  ? 26.221  122.573 -32.810 1.00 60.39  ? 340  LYS   D N     1 
ATOM   5775  C  CA    . LYS   F 3 47  ? 27.275  122.755 -31.818 1.00 65.72  ? 340  LYS   D CA    1 
ATOM   5776  C  C     . LYS   F 3 47  ? 26.961  121.935 -30.574 1.00 60.11  ? 340  LYS   D C     1 
ATOM   5777  O  O     . LYS   F 3 47  ? 27.862  121.567 -29.821 1.00 62.09  ? 340  LYS   D O     1 
ATOM   5778  C  CB    . LYS   F 3 47  ? 27.433  124.235 -31.450 1.00 77.72  ? 340  LYS   D CB    1 
ATOM   5779  C  CG    . LYS   F 3 47  ? 27.428  125.179 -32.648 1.00 88.37  ? 340  LYS   D CG    1 
ATOM   5780  C  CD    . LYS   F 3 47  ? 28.233  126.449 -32.464 1.00 96.24  ? 340  LYS   D CD    1 
ATOM   5781  C  CE    . LYS   F 3 47  ? 28.565  127.116 -33.786 1.00 100.79 ? 340  LYS   D CE    1 
ATOM   5782  N  NZ    . LYS   F 3 47  ? 29.561  128.199 -33.610 1.00 103.07 ? 340  LYS   D NZ    1 
ATOM   5783  N  N     . ALA   F 3 48  ? 25.664  121.676 -30.378 1.00 59.33  ? 341  ALA   D N     1 
ATOM   5784  C  CA    . ALA   F 3 48  ? 25.158  120.921 -29.241 1.00 60.90  ? 341  ALA   D CA    1 
ATOM   5785  C  C     . ALA   F 3 48  ? 25.511  119.432 -29.343 1.00 58.99  ? 341  ALA   D C     1 
ATOM   5786  O  O     . ALA   F 3 48  ? 25.539  118.735 -28.323 1.00 48.36  ? 341  ALA   D O     1 
ATOM   5787  C  CB    . ALA   F 3 48  ? 23.666  121.134 -29.151 1.00 63.78  ? 341  ALA   D CB    1 
ATOM   5788  N  N     . LEU   F 3 49  ? 25.809  118.961 -30.569 1.00 53.70  ? 342  LEU   D N     1 
ATOM   5789  C  CA    . LEU   F 3 49  ? 26.291  117.604 -30.785 1.00 50.38  ? 342  LEU   D CA    1 
ATOM   5790  C  C     . LEU   F 3 49  ? 27.539  117.319 -29.948 1.00 51.79  ? 342  LEU   D C     1 
ATOM   5791  O  O     . LEU   F 3 49  ? 27.734  116.183 -29.522 1.00 51.03  ? 342  LEU   D O     1 
ATOM   5792  C  CB    . LEU   F 3 49  ? 26.578  117.404 -32.276 1.00 49.21  ? 342  LEU   D CB    1 
ATOM   5793  C  CG    . LEU   F 3 49  ? 25.352  117.423 -33.192 1.00 50.61  ? 342  LEU   D CG    1 
ATOM   5794  C  CD1   . LEU   F 3 49  ? 25.756  117.360 -34.663 1.00 45.02  ? 342  LEU   D CD1   1 
ATOM   5795  C  CD2   . LEU   F 3 49  ? 24.403  116.276 -32.850 1.00 52.37  ? 342  LEU   D CD2   1 
ATOM   5796  N  N     . ARG   F 3 50  ? 28.387  118.338 -29.723 1.00 61.52  ? 343  ARG   D N     1 
ATOM   5797  C  CA    . ARG   F 3 50  ? 29.647  118.176 -29.000 1.00 61.87  ? 343  ARG   D CA    1 
ATOM   5798  C  C     . ARG   F 3 50  ? 29.421  117.776 -27.543 1.00 58.34  ? 343  ARG   D C     1 
ATOM   5799  O  O     . ARG   F 3 50  ? 30.335  117.251 -26.913 1.00 59.37  ? 343  ARG   D O     1 
ATOM   5800  C  CB    . ARG   F 3 50  ? 30.473  119.468 -28.972 1.00 67.80  ? 343  ARG   D CB    1 
ATOM   5801  C  CG    . ARG   F 3 50  ? 31.387  119.677 -30.167 1.00 71.92  ? 343  ARG   D CG    1 
ATOM   5802  C  CD    . ARG   F 3 50  ? 30.587  119.922 -31.426 1.00 82.82  ? 343  ARG   D CD    1 
ATOM   5803  N  NE    . ARG   F 3 50  ? 31.434  120.357 -32.524 1.00 95.12  ? 343  ARG   D NE    1 
ATOM   5804  C  CZ    . ARG   F 3 50  ? 31.034  120.468 -33.785 1.00 100.40 ? 343  ARG   D CZ    1 
ATOM   5805  N  NH1   . ARG   F 3 50  ? 29.805  120.125 -34.132 1.00 94.99  ? 343  ARG   D NH1   1 
ATOM   5806  N  NH2   . ARG   F 3 50  ? 31.875  120.921 -34.697 1.00 106.01 ? 343  ARG   D NH2   1 
ATOM   5807  N  N     . ASP   F 3 51  ? 28.227  118.063 -27.005 1.00 58.71  ? 344  ASP   D N     1 
ATOM   5808  C  CA    . ASP   F 3 51  ? 27.961  117.897 -25.583 1.00 63.96  ? 344  ASP   D CA    1 
ATOM   5809  C  C     . ASP   F 3 51  ? 27.549  116.457 -25.256 1.00 69.53  ? 344  ASP   D C     1 
ATOM   5810  O  O     . ASP   F 3 51  ? 27.672  116.030 -24.110 1.00 67.91  ? 344  ASP   D O     1 
ATOM   5811  C  CB    . ASP   F 3 51  ? 26.934  118.932 -25.118 1.00 63.85  ? 344  ASP   D CB    1 
ATOM   5812  C  CG    . ASP   F 3 51  ? 27.415  120.361 -25.320 1.00 62.63  ? 344  ASP   D CG    1 
ATOM   5813  O  OD1   . ASP   F 3 51  ? 28.563  120.640 -24.932 1.00 59.64  ? 344  ASP   D OD1   1 
ATOM   5814  O  OD2   . ASP   F 3 51  ? 26.651  121.173 -25.884 1.00 60.39  ? 344  ASP   D OD2   1 
ATOM   5815  N  N     . LEU   F 3 52  ? 27.093  115.708 -26.270 1.00 65.57  ? 345  LEU   D N     1 
ATOM   5816  C  CA    . LEU   F 3 52  ? 26.657  114.330 -26.105 1.00 59.31  ? 345  LEU   D CA    1 
ATOM   5817  C  C     . LEU   F 3 52  ? 27.852  113.391 -26.219 1.00 55.79  ? 345  LEU   D C     1 
ATOM   5818  O  O     . LEU   F 3 52  ? 28.723  113.608 -27.061 1.00 57.62  ? 345  LEU   D O     1 
ATOM   5819  C  CB    . LEU   F 3 52  ? 25.620  114.031 -27.194 1.00 54.17  ? 345  LEU   D CB    1 
ATOM   5820  C  CG    . LEU   F 3 52  ? 24.394  114.934 -27.159 1.00 51.69  ? 345  LEU   D CG    1 
ATOM   5821  C  CD1   . LEU   F 3 52  ? 23.466  114.663 -28.331 1.00 52.51  ? 345  LEU   D CD1   1 
ATOM   5822  C  CD2   . LEU   F 3 52  ? 23.668  114.756 -25.834 1.00 54.78  ? 345  LEU   D CD2   1 
ATOM   5823  N  N     . LYS   F 3 53  ? 27.852  112.339 -25.391 1.00 59.96  ? 346  LYS   D N     1 
ATOM   5824  C  CA    . LYS   F 3 53  ? 28.848  111.275 -25.458 1.00 63.12  ? 346  LYS   D CA    1 
ATOM   5825  C  C     . LYS   F 3 53  ? 28.492  110.233 -26.528 1.00 56.48  ? 346  LYS   D C     1 
ATOM   5826  O  O     . LYS   F 3 53  ? 29.357  109.509 -27.027 1.00 54.85  ? 346  LYS   D O     1 
ATOM   5827  C  CB    . LYS   F 3 53  ? 28.961  110.593 -24.090 1.00 71.90  ? 346  LYS   D CB    1 
ATOM   5828  C  CG    . LYS   F 3 53  ? 29.956  111.200 -23.107 1.00 80.27  ? 346  LYS   D CG    1 
ATOM   5829  C  CD    . LYS   F 3 53  ? 30.541  110.146 -22.167 1.00 92.78  ? 346  LYS   D CD    1 
ATOM   5830  C  CE    . LYS   F 3 53  ? 31.909  110.496 -21.613 1.00 98.32  ? 346  LYS   D CE    1 
ATOM   5831  N  NZ    . LYS   F 3 53  ? 31.827  111.611 -20.641 1.00 97.24  ? 346  LYS   D NZ    1 
ATOM   5832  N  N     . GLU   F 3 54  ? 27.193  110.116 -26.823 1.00 53.33  ? 347  GLU   D N     1 
ATOM   5833  C  CA    . GLU   F 3 54  ? 26.677  109.188 -27.815 1.00 50.26  ? 347  GLU   D CA    1 
ATOM   5834  C  C     . GLU   F 3 54  ? 25.291  109.677 -28.213 1.00 46.37  ? 347  GLU   D C     1 
ATOM   5835  O  O     . GLU   F 3 54  ? 24.677  110.435 -27.468 1.00 46.20  ? 347  GLU   D O     1 
ATOM   5836  C  CB    . GLU   F 3 54  ? 26.624  107.749 -27.268 1.00 50.71  ? 347  GLU   D CB    1 
ATOM   5837  C  CG    . GLU   F 3 54  ? 25.689  107.576 -26.080 1.00 54.37  ? 347  GLU   D CG    1 
ATOM   5838  C  CD    . GLU   F 3 54  ? 25.542  106.181 -25.483 1.00 62.00  ? 347  GLU   D CD    1 
ATOM   5839  O  OE1   . GLU   F 3 54  ? 26.010  105.189 -26.100 1.00 64.21  ? 347  GLU   D OE1   1 
ATOM   5840  O  OE2   . GLU   F 3 54  ? 24.963  106.088 -24.378 1.00 66.68  ? 347  GLU   D OE2   1 
ATOM   5841  N  N     . ALA   F 3 55  ? 24.804  109.219 -29.372 1.00 45.03  ? 348  ALA   D N     1 
ATOM   5842  C  CA    . ALA   F 3 55  ? 23.405  109.370 -29.743 1.00 41.57  ? 348  ALA   D CA    1 
ATOM   5843  C  C     . ALA   F 3 55  ? 22.592  108.145 -29.315 1.00 39.84  ? 348  ALA   D C     1 
ATOM   5844  O  O     . ALA   F 3 55  ? 22.729  107.072 -29.902 1.00 38.51  ? 348  ALA   D O     1 
ATOM   5845  C  CB    . ALA   F 3 55  ? 23.324  109.601 -31.235 1.00 43.26  ? 348  ALA   D CB    1 
ATOM   5846  N  N     . ARG   F 3 56  ? 21.762  108.312 -28.274 1.00 45.09  ? 349  ARG   D N     1 
ATOM   5847  C  CA    . ARG   F 3 56  ? 20.825  107.301 -27.799 1.00 42.96  ? 349  ARG   D CA    1 
ATOM   5848  C  C     . ARG   F 3 56  ? 19.405  107.723 -28.146 1.00 45.00  ? 349  ARG   D C     1 
ATOM   5849  O  O     . ARG   F 3 56  ? 18.920  108.721 -27.622 1.00 48.03  ? 349  ARG   D O     1 
ATOM   5850  C  CB    . ARG   F 3 56  ? 20.753  107.198 -26.276 1.00 45.04  ? 349  ARG   D CB    1 
ATOM   5851  C  CG    . ARG   F 3 56  ? 22.011  106.716 -25.583 1.00 53.70  ? 349  ARG   D CG    1 
ATOM   5852  C  CD    . ARG   F 3 56  ? 21.736  106.617 -24.092 1.00 55.23  ? 349  ARG   D CD    1 
ATOM   5853  N  NE    . ARG   F 3 56  ? 20.935  105.450 -23.759 1.00 55.80  ? 349  ARG   D NE    1 
ATOM   5854  C  CZ    . ARG   F 3 56  ? 20.292  105.270 -22.609 1.00 58.48  ? 349  ARG   D CZ    1 
ATOM   5855  N  NH1   . ARG   F 3 56  ? 20.070  106.290 -21.800 1.00 57.26  ? 349  ARG   D NH1   1 
ATOM   5856  N  NH2   . ARG   F 3 56  ? 19.836  104.072 -22.292 1.00 54.54  ? 349  ARG   D NH2   1 
ATOM   5857  N  N     . GLY   F 3 57  ? 18.711  106.939 -28.969 1.00 40.51  ? 350  GLY   D N     1 
ATOM   5858  C  CA    . GLY   F 3 57  ? 17.316  107.226 -29.214 1.00 36.76  ? 350  GLY   D CA    1 
ATOM   5859  C  C     . GLY   F 3 57  ? 16.898  106.777 -30.597 1.00 38.01  ? 350  GLY   D C     1 
ATOM   5860  O  O     . GLY   F 3 57  ? 17.662  106.124 -31.301 1.00 41.42  ? 350  GLY   D O     1 
ATOM   5861  N  N     . LEU   F 3 58  ? 15.670  107.153 -30.963 1.00 35.59  ? 351  LEU   D N     1 
ATOM   5862  C  CA    . LEU   F 3 58  ? 15.115  106.726 -32.223 1.00 35.18  ? 351  LEU   D CA    1 
ATOM   5863  C  C     . LEU   F 3 58  ? 16.025  107.213 -33.349 1.00 38.40  ? 351  LEU   D C     1 
ATOM   5864  O  O     . LEU   F 3 58  ? 16.414  108.377 -33.371 1.00 37.23  ? 351  LEU   D O     1 
ATOM   5865  C  CB    . LEU   F 3 58  ? 13.695  107.271 -32.349 1.00 35.36  ? 351  LEU   D CB    1 
ATOM   5866  C  CG    . LEU   F 3 58  ? 12.664  106.646 -31.414 1.00 38.31  ? 351  LEU   D CG    1 
ATOM   5867  C  CD1   . LEU   F 3 58  ? 11.374  107.456 -31.436 1.00 41.96  ? 351  LEU   D CD1   1 
ATOM   5868  C  CD2   . LEU   F 3 58  ? 12.383  105.200 -31.792 1.00 37.95  ? 351  LEU   D CD2   1 
ATOM   5869  N  N     . LEU   F 3 59  ? 16.354  106.284 -34.261 1.00 36.49  ? 352  LEU   D N     1 
ATOM   5870  C  CA    . LEU   F 3 59  ? 17.128  106.544 -35.457 1.00 34.66  ? 352  LEU   D CA    1 
ATOM   5871  C  C     . LEU   F 3 59  ? 18.493  107.114 -35.085 1.00 32.38  ? 352  LEU   D C     1 
ATOM   5872  O  O     . LEU   F 3 59  ? 19.011  107.965 -35.793 1.00 31.86  ? 352  LEU   D O     1 
ATOM   5873  C  CB    . LEU   F 3 59  ? 16.343  107.485 -36.375 1.00 36.72  ? 352  LEU   D CB    1 
ATOM   5874  C  CG    . LEU   F 3 59  ? 14.941  107.017 -36.760 1.00 39.12  ? 352  LEU   D CG    1 
ATOM   5875  C  CD1   . LEU   F 3 59  ? 14.238  108.074 -37.623 1.00 36.16  ? 352  LEU   D CD1   1 
ATOM   5876  C  CD2   . LEU   F 3 59  ? 14.983  105.681 -37.489 1.00 41.83  ? 352  LEU   D CD2   1 
ATOM   5877  N  N     . ALA   F 3 60  ? 19.098  106.592 -34.007 1.00 32.00  ? 353  ALA   D N     1 
ATOM   5878  C  CA    . ALA   F 3 60  ? 20.363  107.104 -33.502 1.00 31.74  ? 353  ALA   D CA    1 
ATOM   5879  C  C     . ALA   F 3 60  ? 21.452  107.119 -34.582 1.00 35.00  ? 353  ALA   D C     1 
ATOM   5880  O  O     . ALA   F 3 60  ? 22.280  108.034 -34.622 1.00 40.55  ? 353  ALA   D O     1 
ATOM   5881  C  CB    . ALA   F 3 60  ? 20.795  106.295 -32.306 1.00 32.82  ? 353  ALA   D CB    1 
ATOM   5882  N  N     . LYS   F 3 61  ? 21.483  106.084 -35.426 1.00 33.09  ? 354  LYS   D N     1 
ATOM   5883  C  CA    . LYS   F 3 61  ? 22.526  105.944 -36.425 1.00 33.48  ? 354  LYS   D CA    1 
ATOM   5884  C  C     . LYS   F 3 61  ? 22.494  107.126 -37.397 1.00 32.42  ? 354  LYS   D C     1 
ATOM   5885  O  O     . LYS   F 3 61  ? 23.541  107.590 -37.834 1.00 35.36  ? 354  LYS   D O     1 
ATOM   5886  C  CB    . LYS   F 3 61  ? 22.373  104.607 -37.170 1.00 34.24  ? 354  LYS   D CB    1 
ATOM   5887  C  CG    . LYS   F 3 61  ? 23.328  104.411 -38.346 1.00 34.59  ? 354  LYS   D CG    1 
ATOM   5888  C  CD    . LYS   F 3 61  ? 22.799  103.522 -39.420 1.00 38.82  ? 354  LYS   D CD    1 
ATOM   5889  C  CE    . LYS   F 3 61  ? 21.708  104.196 -40.218 1.00 42.24  ? 354  LYS   D CE    1 
ATOM   5890  N  NZ    . LYS   F 3 61  ? 21.046  103.235 -41.117 1.00 44.02  ? 354  LYS   D NZ    1 
ATOM   5891  N  N     . ASP   F 3 62  ? 21.303  107.558 -37.800 1.00 33.27  ? 355  ASP   D N     1 
ATOM   5892  C  CA    . ASP   F 3 62  ? 21.165  108.632 -38.766 1.00 36.75  ? 355  ASP   D CA    1 
ATOM   5893  C  C     . ASP   F 3 62  ? 21.825  109.912 -38.256 1.00 40.93  ? 355  ASP   D C     1 
ATOM   5894  O  O     . ASP   F 3 62  ? 22.484  110.606 -39.030 1.00 41.77  ? 355  ASP   D O     1 
ATOM   5895  C  CB    . ASP   F 3 62  ? 19.698  108.867 -39.105 1.00 40.86  ? 355  ASP   D CB    1 
ATOM   5896  C  CG    . ASP   F 3 62  ? 19.132  107.791 -40.018 1.00 43.40  ? 355  ASP   D CG    1 
ATOM   5897  O  OD1   . ASP   F 3 62  ? 19.947  107.000 -40.568 1.00 45.43  ? 355  ASP   D OD1   1 
ATOM   5898  O  OD2   . ASP   F 3 62  ? 17.887  107.742 -40.160 1.00 44.04  ? 355  ASP   D OD2   1 
ATOM   5899  N  N     . LEU   F 3 63  ? 21.669  110.205 -36.959 1.00 37.37  ? 356  LEU   D N     1 
ATOM   5900  C  CA    . LEU   F 3 63  ? 22.247  111.409 -36.393 1.00 38.59  ? 356  LEU   D CA    1 
ATOM   5901  C  C     . LEU   F 3 63  ? 23.761  111.266 -36.336 1.00 38.47  ? 356  LEU   D C     1 
ATOM   5902  O  O     . LEU   F 3 63  ? 24.497  112.210 -36.610 1.00 45.79  ? 356  LEU   D O     1 
ATOM   5903  C  CB    . LEU   F 3 63  ? 21.692  111.669 -34.989 1.00 35.61  ? 356  LEU   D CB    1 
ATOM   5904  C  CG    . LEU   F 3 63  ? 22.236  112.932 -34.308 1.00 36.64  ? 356  LEU   D CG    1 
ATOM   5905  C  CD1   . LEU   F 3 63  ? 21.856  114.182 -35.083 1.00 33.89  ? 356  LEU   D CD1   1 
ATOM   5906  C  CD2   . LEU   F 3 63  ? 21.746  113.042 -32.862 1.00 36.46  ? 356  LEU   D CD2   1 
ATOM   5907  N  N     . SER   F 3 64  ? 24.199  110.073 -35.948 1.00 38.31  ? 357  SER   D N     1 
ATOM   5908  C  CA    . SER   F 3 64  ? 25.609  109.757 -35.872 1.00 36.56  ? 357  SER   D CA    1 
ATOM   5909  C  C     . SER   F 3 64  ? 26.287  109.932 -37.238 1.00 36.93  ? 357  SER   D C     1 
ATOM   5910  O  O     . SER   F 3 64  ? 27.429  110.369 -37.322 1.00 40.19  ? 357  SER   D O     1 
ATOM   5911  C  CB    . SER   F 3 64  ? 25.769  108.378 -35.305 1.00 38.13  ? 357  SER   D CB    1 
ATOM   5912  O  OG    . SER   F 3 64  ? 27.135  107.989 -35.341 1.00 43.84  ? 357  SER   D OG    1 
ATOM   5913  N  N     . VAL   F 3 65  ? 25.568  109.629 -38.321 1.00 37.62  ? 358  VAL   D N     1 
ATOM   5914  C  CA    . VAL   F 3 65  ? 26.097  109.780 -39.662 1.00 38.21  ? 358  VAL   D CA    1 
ATOM   5915  C  C     . VAL   F 3 65  ? 26.296  111.258 -39.975 1.00 40.95  ? 358  VAL   D C     1 
ATOM   5916  O  O     . VAL   F 3 65  ? 27.351  111.634 -40.481 1.00 42.77  ? 358  VAL   D O     1 
ATOM   5917  C  CB    . VAL   F 3 65  ? 25.194  109.114 -40.712 1.00 38.02  ? 358  VAL   D CB    1 
ATOM   5918  C  CG1   . VAL   F 3 65  ? 25.582  109.526 -42.130 1.00 37.80  ? 358  VAL   D CG1   1 
ATOM   5919  C  CG2   . VAL   F 3 65  ? 25.216  107.602 -40.565 1.00 38.37  ? 358  VAL   D CG2   1 
ATOM   5920  N  N     . LEU   F 3 66  ? 25.272  112.078 -39.712 1.00 41.68  ? 359  LEU   D N     1 
ATOM   5921  C  CA    . LEU   F 3 66  ? 25.394  113.520 -39.878 1.00 39.90  ? 359  LEU   D CA    1 
ATOM   5922  C  C     . LEU   F 3 66  ? 26.576  114.049 -39.071 1.00 37.79  ? 359  LEU   D C     1 
ATOM   5923  O  O     . LEU   F 3 66  ? 27.346  114.871 -39.554 1.00 42.64  ? 359  LEU   D O     1 
ATOM   5924  C  CB    . LEU   F 3 66  ? 24.098  114.193 -39.420 1.00 43.52  ? 359  LEU   D CB    1 
ATOM   5925  C  CG    . LEU   F 3 66  ? 24.047  115.709 -39.613 1.00 42.98  ? 359  LEU   D CG    1 
ATOM   5926  C  CD1   . LEU   F 3 66  ? 22.810  116.117 -40.395 1.00 43.72  ? 359  LEU   D CD1   1 
ATOM   5927  C  CD2   . LEU   F 3 66  ? 24.112  116.416 -38.271 1.00 42.39  ? 359  LEU   D CD2   1 
ATOM   5928  N  N     . ALA   F 3 67  ? 26.733  113.565 -37.841 1.00 37.86  ? 360  ALA   D N     1 
ATOM   5929  C  CA    . ALA   F 3 67  ? 27.822  114.015 -36.993 1.00 39.51  ? 360  ALA   D CA    1 
ATOM   5930  C  C     . ALA   F 3 67  ? 29.175  113.721 -37.647 1.00 44.97  ? 360  ALA   D C     1 
ATOM   5931  O  O     . ALA   F 3 67  ? 30.016  114.619 -37.728 1.00 50.26  ? 360  ALA   D O     1 
ATOM   5932  C  CB    . ALA   F 3 67  ? 27.705  113.398 -35.626 1.00 38.73  ? 360  ALA   D CB    1 
ATOM   5933  N  N     . LEU   F 3 68  ? 29.371  112.478 -38.126 1.00 44.23  ? 361  LEU   D N     1 
ATOM   5934  C  CA    . LEU   F 3 68  ? 30.592  112.079 -38.812 1.00 40.41  ? 361  LEU   D CA    1 
ATOM   5935  C  C     . LEU   F 3 68  ? 30.887  112.988 -40.015 1.00 41.27  ? 361  LEU   D C     1 
ATOM   5936  O  O     . LEU   F 3 68  ? 32.039  113.357 -40.237 1.00 42.96  ? 361  LEU   D O     1 
ATOM   5937  C  CB    . LEU   F 3 68  ? 30.454  110.622 -39.268 1.00 40.60  ? 361  LEU   D CB    1 
ATOM   5938  C  CG    . LEU   F 3 68  ? 30.596  109.568 -38.177 1.00 40.04  ? 361  LEU   D CG    1 
ATOM   5939  C  CD1   . LEU   F 3 68  ? 30.250  108.197 -38.730 1.00 42.20  ? 361  LEU   D CD1   1 
ATOM   5940  C  CD2   . LEU   F 3 68  ? 32.001  109.548 -37.587 1.00 39.56  ? 361  LEU   D CD2   1 
ATOM   5941  N  N     . ARG   F 3 69  ? 29.867  113.288 -40.827 1.00 37.32  ? 362  ARG   D N     1 
ATOM   5942  C  CA    . ARG   F 3 69  ? 29.981  114.219 -41.939 1.00 39.08  ? 362  ARG   D CA    1 
ATOM   5943  C  C     . ARG   F 3 69  ? 30.592  115.545 -41.479 1.00 46.35  ? 362  ARG   D C     1 
ATOM   5944  O  O     . ARG   F 3 69  ? 31.431  116.115 -42.180 1.00 49.18  ? 362  ARG   D O     1 
ATOM   5945  C  CB    . ARG   F 3 69  ? 28.596  114.485 -42.534 1.00 38.72  ? 362  ARG   D CB    1 
ATOM   5946  C  CG    . ARG   F 3 69  ? 28.587  115.366 -43.779 1.00 38.39  ? 362  ARG   D CG    1 
ATOM   5947  C  CD    . ARG   F 3 69  ? 27.182  115.772 -44.176 1.00 35.99  ? 362  ARG   D CD    1 
ATOM   5948  N  NE    . ARG   F 3 69  ? 26.617  116.713 -43.214 1.00 38.13  ? 362  ARG   D NE    1 
ATOM   5949  C  CZ    . ARG   F 3 69  ? 25.341  117.097 -43.203 1.00 40.29  ? 362  ARG   D CZ    1 
ATOM   5950  N  NH1   . ARG   F 3 69  ? 24.462  116.509 -43.990 1.00 39.91  ? 362  ARG   D NH1   1 
ATOM   5951  N  NH2   . ARG   F 3 69  ? 24.942  118.061 -42.393 1.00 44.23  ? 362  ARG   D NH2   1 
ATOM   5952  N  N     . GLU   F 3 70  ? 30.153  116.016 -40.301 1.00 51.52  ? 363  GLU   D N     1 
ATOM   5953  C  CA    . GLU   F 3 70  ? 30.582  117.285 -39.725 1.00 56.45  ? 363  GLU   D CA    1 
ATOM   5954  C  C     . GLU   F 3 70  ? 31.930  117.156 -39.014 1.00 53.22  ? 363  GLU   D C     1 
ATOM   5955  O  O     . GLU   F 3 70  ? 32.403  118.129 -38.438 1.00 58.79  ? 363  GLU   D O     1 
ATOM   5956  C  CB    . GLU   F 3 70  ? 29.577  117.818 -38.691 1.00 58.07  ? 363  GLU   D CB    1 
ATOM   5957  C  CG    . GLU   F 3 70  ? 28.220  118.214 -39.233 1.00 56.53  ? 363  GLU   D CG    1 
ATOM   5958  C  CD    . GLU   F 3 70  ? 28.192  118.988 -40.537 1.00 63.58  ? 363  GLU   D CD    1 
ATOM   5959  O  OE1   . GLU   F 3 70  ? 28.969  119.950 -40.681 1.00 66.55  ? 363  GLU   D OE1   1 
ATOM   5960  O  OE2   . GLU   F 3 70  ? 27.361  118.635 -41.402 1.00 72.73  ? 363  GLU   D OE2   1 
ATOM   5961  N  N     . GLY   F 3 71  ? 32.522  115.955 -39.010 1.00 53.27  ? 364  GLY   D N     1 
ATOM   5962  C  CA    . GLY   F 3 71  ? 33.836  115.721 -38.431 1.00 46.17  ? 364  GLY   D CA    1 
ATOM   5963  C  C     . GLY   F 3 71  ? 33.782  115.346 -36.952 1.00 48.94  ? 364  GLY   D C     1 
ATOM   5964  O  O     . GLY   F 3 71  ? 34.807  115.376 -36.277 1.00 49.57  ? 364  GLY   D O     1 
ATOM   5965  N  N     . LEU   F 3 72  ? 32.602  114.965 -36.448 1.00 52.43  ? 365  LEU   D N     1 
ATOM   5966  C  CA    . LEU   F 3 72  ? 32.464  114.614 -35.042 1.00 54.73  ? 365  LEU   D CA    1 
ATOM   5967  C  C     . LEU   F 3 72  ? 32.154  113.121 -34.900 1.00 55.53  ? 365  LEU   D C     1 
ATOM   5968  O  O     . LEU   F 3 72  ? 31.277  112.593 -35.587 1.00 60.77  ? 365  LEU   D O     1 
ATOM   5969  C  CB    . LEU   F 3 72  ? 31.372  115.498 -34.427 1.00 61.26  ? 365  LEU   D CB    1 
ATOM   5970  C  CG    . LEU   F 3 72  ? 31.061  115.241 -32.952 1.00 70.78  ? 365  LEU   D CG    1 
ATOM   5971  C  CD1   . LEU   F 3 72  ? 32.269  115.527 -32.063 1.00 75.73  ? 365  LEU   D CD1   1 
ATOM   5972  C  CD2   . LEU   F 3 72  ? 29.863  116.066 -32.506 1.00 73.98  ? 365  LEU   D CD2   1 
ATOM   5973  N  N     . GLY   F 3 73  ? 32.882  112.462 -33.986 1.00 52.86  ? 366  GLY   D N     1 
ATOM   5974  C  CA    . GLY   F 3 73  ? 32.717  111.048 -33.686 1.00 50.31  ? 366  GLY   D CA    1 
ATOM   5975  C  C     . GLY   F 3 73  ? 31.739  110.840 -32.531 1.00 52.59  ? 366  GLY   D C     1 
ATOM   5976  O  O     . GLY   F 3 73  ? 32.144  110.714 -31.376 1.00 54.17  ? 366  GLY   D O     1 
ATOM   5977  N  N     . LEU   F 3 74  ? 30.442  110.846 -32.864 1.00 52.18  ? 367  LEU   D N     1 
ATOM   5978  C  CA    . LEU   F 3 74  ? 29.364  110.647 -31.904 1.00 52.06  ? 367  LEU   D CA    1 
ATOM   5979  C  C     . LEU   F 3 74  ? 28.708  109.300 -32.209 1.00 48.57  ? 367  LEU   D C     1 
ATOM   5980  O  O     . LEU   F 3 74  ? 27.885  109.187 -33.125 1.00 40.74  ? 367  LEU   D O     1 
ATOM   5981  C  CB    . LEU   F 3 74  ? 28.370  111.809 -32.038 1.00 49.73  ? 367  LEU   D CB    1 
ATOM   5982  C  CG    . LEU   F 3 74  ? 27.181  111.791 -31.085 1.00 46.79  ? 367  LEU   D CG    1 
ATOM   5983  C  CD1   . LEU   F 3 74  ? 27.599  112.232 -29.697 1.00 48.07  ? 367  LEU   D CD1   1 
ATOM   5984  C  CD2   . LEU   F 3 74  ? 26.069  112.684 -31.603 1.00 48.74  ? 367  LEU   D CD2   1 
ATOM   5985  N  N     . PRO   F 3 75  ? 29.101  108.221 -31.496 1.00 47.54  ? 368  PRO   D N     1 
ATOM   5986  C  CA    . PRO   F 3 75  ? 28.663  106.880 -31.867 1.00 46.89  ? 368  PRO   D CA    1 
ATOM   5987  C  C     . PRO   F 3 75  ? 27.187  106.731 -31.513 1.00 50.10  ? 368  PRO   D C     1 
ATOM   5988  O  O     . PRO   F 3 75  ? 26.701  107.351 -30.568 1.00 48.35  ? 368  PRO   D O     1 
ATOM   5989  C  CB    . PRO   F 3 75  ? 29.600  105.966 -31.056 1.00 46.16  ? 368  PRO   D CB    1 
ATOM   5990  C  CG    . PRO   F 3 75  ? 29.923  106.780 -29.822 1.00 45.30  ? 368  PRO   D CG    1 
ATOM   5991  C  CD    . PRO   F 3 75  ? 29.972  108.221 -30.306 1.00 46.51  ? 368  PRO   D CD    1 
ATOM   5992  N  N     . PRO   F 3 76  ? 26.417  105.929 -32.277 1.00 49.69  ? 369  PRO   D N     1 
ATOM   5993  C  CA    . PRO   F 3 76  ? 25.051  105.607 -31.885 1.00 47.24  ? 369  PRO   D CA    1 
ATOM   5994  C  C     . PRO   F 3 76  ? 25.069  104.560 -30.772 1.00 47.19  ? 369  PRO   D C     1 
ATOM   5995  O  O     . PRO   F 3 76  ? 25.936  103.683 -30.746 1.00 45.30  ? 369  PRO   D O     1 
ATOM   5996  C  CB    . PRO   F 3 76  ? 24.436  105.118 -33.202 1.00 47.54  ? 369  PRO   D CB    1 
ATOM   5997  C  CG    . PRO   F 3 76  ? 25.594  104.500 -33.954 1.00 46.46  ? 369  PRO   D CG    1 
ATOM   5998  C  CD    . PRO   F 3 76  ? 26.829  105.261 -33.517 1.00 47.84  ? 369  PRO   D CD    1 
ATOM   5999  N  N     . GLY   F 3 77  ? 24.143  104.704 -29.815 1.00 45.69  ? 370  GLY   D N     1 
ATOM   6000  C  CA    . GLY   F 3 77  ? 23.898  103.684 -28.802 1.00 41.18  ? 370  GLY   D CA    1 
ATOM   6001  C  C     . GLY   F 3 77  ? 22.465  103.156 -28.881 1.00 38.07  ? 370  GLY   D C     1 
ATOM   6002  O  O     . GLY   F 3 77  ? 21.971  102.845 -29.960 1.00 42.03  ? 370  GLY   D O     1 
ATOM   6003  N  N     . ASP   F 3 78  ? 21.792  103.071 -27.731 1.00 38.94  ? 371  ASP   D N     1 
ATOM   6004  C  CA    . ASP   F 3 78  ? 20.474  102.460 -27.650 1.00 37.42  ? 371  ASP   D CA    1 
ATOM   6005  C  C     . ASP   F 3 78  ? 19.556  103.110 -28.678 1.00 34.92  ? 371  ASP   D C     1 
ATOM   6006  O  O     . ASP   F 3 78  ? 19.619  104.320 -28.887 1.00 33.89  ? 371  ASP   D O     1 
ATOM   6007  C  CB    . ASP   F 3 78  ? 19.878  102.543 -26.234 1.00 37.24  ? 371  ASP   D CB    1 
ATOM   6008  C  CG    . ASP   F 3 78  ? 20.492  101.590 -25.219 1.00 39.91  ? 371  ASP   D CG    1 
ATOM   6009  O  OD1   . ASP   F 3 78  ? 20.632  100.380 -25.536 1.00 41.69  ? 371  ASP   D OD1   1 
ATOM   6010  O  OD2   . ASP   F 3 78  ? 20.808  102.051 -24.110 1.00 38.62  ? 371  ASP   D OD2   1 
ATOM   6011  N  N     . ASP   F 3 79  ? 18.712  102.289 -29.313 1.00 31.84  ? 372  ASP   D N     1 
ATOM   6012  C  CA    . ASP   F 3 79  ? 17.703  102.786 -30.234 1.00 32.86  ? 372  ASP   D CA    1 
ATOM   6013  C  C     . ASP   F 3 79  ? 16.486  101.871 -30.124 1.00 34.59  ? 372  ASP   D C     1 
ATOM   6014  O  O     . ASP   F 3 79  ? 16.554  100.700 -30.486 1.00 35.14  ? 372  ASP   D O     1 
ATOM   6015  C  CB    . ASP   F 3 79  ? 18.249  102.884 -31.660 1.00 30.87  ? 372  ASP   D CB    1 
ATOM   6016  C  CG    . ASP   F 3 79  ? 17.240  103.351 -32.695 1.00 31.98  ? 372  ASP   D CG    1 
ATOM   6017  O  OD1   . ASP   F 3 79  ? 16.054  103.466 -32.345 1.00 34.97  ? 372  ASP   D OD1   1 
ATOM   6018  O  OD2   . ASP   F 3 79  ? 17.648  103.579 -33.862 1.00 30.85  ? 372  ASP   D OD2   1 
ATOM   6019  N  N     . PRO   F 3 80  ? 15.347  102.374 -29.597 1.00 36.60  ? 373  PRO   D N     1 
ATOM   6020  C  CA    . PRO   F 3 80  ? 14.117  101.584 -29.499 1.00 38.18  ? 373  PRO   D CA    1 
ATOM   6021  C  C     . PRO   F 3 80  ? 13.658  100.905 -30.788 1.00 36.55  ? 373  PRO   D C     1 
ATOM   6022  O  O     . PRO   F 3 80  ? 13.003  99.871  -30.727 1.00 41.23  ? 373  PRO   D O     1 
ATOM   6023  C  CB    . PRO   F 3 80  ? 13.065  102.640 -29.093 1.00 38.20  ? 373  PRO   D CB    1 
ATOM   6024  C  CG    . PRO   F 3 80  ? 13.867  103.649 -28.296 1.00 35.95  ? 373  PRO   D CG    1 
ATOM   6025  C  CD    . PRO   F 3 80  ? 15.179  103.735 -29.050 1.00 36.13  ? 373  PRO   D CD    1 
ATOM   6026  N  N     . MET   F 3 81  ? 13.976  101.493 -31.949 1.00 35.13  ? 374  MET   D N     1 
ATOM   6027  C  CA    . MET   F 3 81  ? 13.663  100.871 -33.230 1.00 35.72  ? 374  MET   D CA    1 
ATOM   6028  C  C     . MET   F 3 81  ? 14.260  99.466  -33.325 1.00 33.73  ? 374  MET   D C     1 
ATOM   6029  O  O     . MET   F 3 81  ? 13.615  98.572  -33.867 1.00 33.66  ? 374  MET   D O     1 
ATOM   6030  C  CB    . MET   F 3 81  ? 14.211  101.688 -34.403 1.00 39.38  ? 374  MET   D CB    1 
ATOM   6031  C  CG    . MET   F 3 81  ? 13.412  102.949 -34.699 1.00 40.78  ? 374  MET   D CG    1 
ATOM   6032  S  SD    . MET   F 3 81  ? 11.652  102.661 -34.906 1.00 37.83  ? 374  MET   D SD    1 
ATOM   6033  C  CE    . MET   F 3 81  ? 11.594  101.291 -36.054 1.00 36.51  ? 374  MET   D CE    1 
ATOM   6034  N  N     . LEU   F 3 82  ? 15.477  99.280  -32.785 1.00 32.92  ? 375  LEU   D N     1 
ATOM   6035  C  CA    . LEU   F 3 82  ? 16.163  97.996  -32.830 1.00 34.25  ? 375  LEU   D CA    1 
ATOM   6036  C  C     . LEU   F 3 82  ? 15.487  96.992  -31.893 1.00 32.90  ? 375  LEU   D C     1 
ATOM   6037  O  O     . LEU   F 3 82  ? 15.350  95.814  -32.238 1.00 32.87  ? 375  LEU   D O     1 
ATOM   6038  C  CB    . LEU   F 3 82  ? 17.646  98.194  -32.479 1.00 32.33  ? 375  LEU   D CB    1 
ATOM   6039  C  CG    . LEU   F 3 82  ? 18.436  99.054  -33.461 1.00 32.48  ? 375  LEU   D CG    1 
ATOM   6040  C  CD1   . LEU   F 3 82  ? 19.877  99.183  -33.033 1.00 33.23  ? 375  LEU   D CD1   1 
ATOM   6041  C  CD2   . LEU   F 3 82  ? 18.362  98.495  -34.874 1.00 33.74  ? 375  LEU   D CD2   1 
ATOM   6042  N  N     . LEU   F 3 83  ? 15.087  97.455  -30.698 1.00 33.45  ? 376  LEU   D N     1 
ATOM   6043  C  CA    . LEU   F 3 83  ? 14.311  96.636  -29.775 1.00 29.57  ? 376  LEU   D CA    1 
ATOM   6044  C  C     . LEU   F 3 83  ? 13.033  96.180  -30.459 1.00 27.13  ? 376  LEU   D C     1 
ATOM   6045  O  O     . LEU   F 3 83  ? 12.682  95.013  -30.416 1.00 31.25  ? 376  LEU   D O     1 
ATOM   6046  C  CB    . LEU   F 3 83  ? 13.975  97.434  -28.513 1.00 30.61  ? 376  LEU   D CB    1 
ATOM   6047  C  CG    . LEU   F 3 83  ? 15.156  97.818  -27.625 1.00 31.37  ? 376  LEU   D CG    1 
ATOM   6048  C  CD1   . LEU   F 3 83  ? 14.677  98.663  -26.448 1.00 33.81  ? 376  LEU   D CD1   1 
ATOM   6049  C  CD2   . LEU   F 3 83  ? 15.897  96.582  -27.136 1.00 31.51  ? 376  LEU   D CD2   1 
ATOM   6050  N  N     . ALA   F 3 84  ? 12.353  97.118  -31.105 1.00 29.77  ? 377  ALA   D N     1 
ATOM   6051  C  CA    . ALA   F 3 84  ? 11.067  96.850  -31.729 1.00 30.08  ? 377  ALA   D CA    1 
ATOM   6052  C  C     . ALA   F 3 84  ? 11.209  95.893  -32.910 1.00 29.05  ? 377  ALA   D C     1 
ATOM   6053  O  O     . ALA   F 3 84  ? 10.370  95.014  -33.111 1.00 31.63  ? 377  ALA   D O     1 
ATOM   6054  C  CB    . ALA   F 3 84  ? 10.456  98.161  -32.157 1.00 31.56  ? 377  ALA   D CB    1 
ATOM   6055  N  N     . TYR   F 3 85  ? 12.232  96.126  -33.735 1.00 27.27  ? 378  TYR   D N     1 
ATOM   6056  C  CA    . TYR   F 3 85  ? 12.510  95.288  -34.889 1.00 26.54  ? 378  TYR   D CA    1 
ATOM   6057  C  C     . TYR   F 3 85  ? 12.753  93.839  -34.445 1.00 29.23  ? 378  TYR   D C     1 
ATOM   6058  O  O     . TYR   F 3 85  ? 12.399  92.904  -35.158 1.00 31.47  ? 378  TYR   D O     1 
ATOM   6059  C  CB    . TYR   F 3 85  ? 13.707  95.866  -35.661 1.00 25.18  ? 378  TYR   D CB    1 
ATOM   6060  C  CG    . TYR   F 3 85  ? 14.091  95.131  -36.926 1.00 25.99  ? 378  TYR   D CG    1 
ATOM   6061  C  CD1   . TYR   F 3 85  ? 13.216  95.054  -37.993 1.00 26.09  ? 378  TYR   D CD1   1 
ATOM   6062  C  CD2   . TYR   F 3 85  ? 15.327  94.522  -37.076 1.00 27.48  ? 378  TYR   D CD2   1 
ATOM   6063  C  CE1   . TYR   F 3 85  ? 13.554  94.400  -39.165 1.00 27.01  ? 378  TYR   D CE1   1 
ATOM   6064  C  CE2   . TYR   F 3 85  ? 15.669  93.834  -38.233 1.00 26.80  ? 378  TYR   D CE2   1 
ATOM   6065  C  CZ    . TYR   F 3 85  ? 14.786  93.797  -39.292 1.00 26.07  ? 378  TYR   D CZ    1 
ATOM   6066  O  OH    . TYR   F 3 85  ? 15.077  93.147  -40.467 1.00 29.05  ? 378  TYR   D OH    1 
ATOM   6067  N  N     . LEU   F 3 86  ? 13.405  93.647  -33.287 1.00 30.53  ? 379  LEU   D N     1 
ATOM   6068  C  CA    . LEU   F 3 86  ? 13.715  92.310  -32.787 1.00 29.89  ? 379  LEU   D CA    1 
ATOM   6069  C  C     . LEU   F 3 86  ? 12.473  91.648  -32.199 1.00 29.31  ? 379  LEU   D C     1 
ATOM   6070  O  O     . LEU   F 3 86  ? 12.290  90.442  -32.351 1.00 31.39  ? 379  LEU   D O     1 
ATOM   6071  C  CB    . LEU   F 3 86  ? 14.840  92.386  -31.747 1.00 29.99  ? 379  LEU   D CB    1 
ATOM   6072  C  CG    . LEU   F 3 86  ? 16.244  92.543  -32.331 1.00 30.26  ? 379  LEU   D CG    1 
ATOM   6073  C  CD1   . LEU   F 3 86  ? 17.244  92.909  -31.248 1.00 30.83  ? 379  LEU   D CD1   1 
ATOM   6074  C  CD2   . LEU   F 3 86  ? 16.690  91.270  -33.051 1.00 29.84  ? 379  LEU   D CD2   1 
ATOM   6075  N  N     . LEU   F 3 87  ? 11.623  92.440  -31.542 1.00 31.00  ? 380  LEU   D N     1 
ATOM   6076  C  CA    . LEU   F 3 87  ? 10.347  91.965  -31.022 1.00 32.49  ? 380  LEU   D CA    1 
ATOM   6077  C  C     . LEU   F 3 87  ? 9.464   91.456  -32.164 1.00 31.87  ? 380  LEU   D C     1 
ATOM   6078  O  O     . LEU   F 3 87  ? 8.846   90.402  -32.043 1.00 29.29  ? 380  LEU   D O     1 
ATOM   6079  C  CB    . LEU   F 3 87  ? 9.705   93.136  -30.272 1.00 36.36  ? 380  LEU   D CB    1 
ATOM   6080  C  CG    . LEU   F 3 87  ? 8.488   92.824  -29.403 1.00 40.95  ? 380  LEU   D CG    1 
ATOM   6081  C  CD1   . LEU   F 3 87  ? 8.817   91.884  -28.249 1.00 40.68  ? 380  LEU   D CD1   1 
ATOM   6082  C  CD2   . LEU   F 3 87  ? 7.931   94.125  -28.850 1.00 44.86  ? 380  LEU   D CD2   1 
ATOM   6083  N  N     . ASP   F 3 88  ? 9.467   92.194  -33.289 1.00 31.44  ? 381  ASP   D N     1 
ATOM   6084  C  CA    . ASP   F 3 88  ? 8.680   91.875  -34.471 1.00 32.40  ? 381  ASP   D CA    1 
ATOM   6085  C  C     . ASP   F 3 88  ? 9.228   92.685  -35.653 1.00 31.07  ? 381  ASP   D C     1 
ATOM   6086  O  O     . ASP   F 3 88  ? 9.112   93.909  -35.666 1.00 29.95  ? 381  ASP   D O     1 
ATOM   6087  C  CB    . ASP   F 3 88  ? 7.206   92.155  -34.174 1.00 33.91  ? 381  ASP   D CB    1 
ATOM   6088  C  CG    . ASP   F 3 88  ? 6.226   91.735  -35.247 1.00 34.38  ? 381  ASP   D CG    1 
ATOM   6089  O  OD1   . ASP   F 3 88  ? 6.644   91.527  -36.405 1.00 34.09  ? 381  ASP   D OD1   1 
ATOM   6090  O  OD2   . ASP   F 3 88  ? 5.039   91.594  -34.880 1.00 39.80  ? 381  ASP   D OD2   1 
ATOM   6091  N  N     . PRO   F 3 89  ? 9.877   92.049  -36.657 1.00 29.30  ? 382  PRO   D N     1 
ATOM   6092  C  CA    . PRO   F 3 89  ? 10.494  92.774  -37.772 1.00 29.76  ? 382  PRO   D CA    1 
ATOM   6093  C  C     . PRO   F 3 89  ? 9.524   93.445  -38.750 1.00 33.71  ? 382  PRO   D C     1 
ATOM   6094  O  O     . PRO   F 3 89  ? 9.968   94.050  -39.735 1.00 37.23  ? 382  PRO   D O     1 
ATOM   6095  C  CB    . PRO   F 3 89  ? 11.313  91.673  -38.469 1.00 28.92  ? 382  PRO   D CB    1 
ATOM   6096  C  CG    . PRO   F 3 89  ? 10.535  90.415  -38.204 1.00 28.24  ? 382  PRO   D CG    1 
ATOM   6097  C  CD    . PRO   F 3 89  ? 10.073  90.588  -36.767 1.00 30.93  ? 382  PRO   D CD    1 
ATOM   6098  N  N     . SER   F 3 90  ? 8.209   93.331  -38.475 1.00 33.47  ? 383  SER   D N     1 
ATOM   6099  C  CA    . SER   F 3 90  ? 7.202   94.196  -39.082 1.00 34.58  ? 383  SER   D CA    1 
ATOM   6100  C  C     . SER   F 3 90  ? 7.236   95.600  -38.465 1.00 33.37  ? 383  SER   D C     1 
ATOM   6101  O  O     . SER   F 3 90  ? 6.667   96.539  -39.014 1.00 32.28  ? 383  SER   D O     1 
ATOM   6102  C  CB    . SER   F 3 90  ? 5.818   93.584  -39.010 1.00 33.31  ? 383  SER   D CB    1 
ATOM   6103  O  OG    . SER   F 3 90  ? 5.350   93.513  -37.670 1.00 33.85  ? 383  SER   D OG    1 
ATOM   6104  N  N     . ASN   F 3 91  ? 7.963   95.778  -37.359 1.00 30.62  ? 384  ASN   D N     1 
ATOM   6105  C  CA    . ASN   F 3 91  ? 8.230   97.118  -36.862 1.00 31.69  ? 384  ASN   D CA    1 
ATOM   6106  C  C     . ASN   F 3 91  ? 9.382   97.761  -37.632 1.00 32.14  ? 384  ASN   D C     1 
ATOM   6107  O  O     . ASN   F 3 91  ? 10.536  97.532  -37.287 1.00 35.45  ? 384  ASN   D O     1 
ATOM   6108  C  CB    . ASN   F 3 91  ? 8.569   97.096  -35.373 1.00 29.69  ? 384  ASN   D CB    1 
ATOM   6109  C  CG    . ASN   F 3 91  ? 7.390   96.609  -34.559 1.00 34.13  ? 384  ASN   D CG    1 
ATOM   6110  O  OD1   . ASN   F 3 91  ? 6.258   97.032  -34.818 1.00 28.19  ? 384  ASN   D OD1   1 
ATOM   6111  N  ND2   . ASN   F 3 91  ? 7.645   95.694  -33.629 1.00 31.16  ? 384  ASN   D ND2   1 
ATOM   6112  N  N     . THR   F 3 92  ? 9.072   98.625  -38.610 1.00 32.86  ? 385  THR   D N     1 
ATOM   6113  C  CA    . THR   F 3 92  ? 10.108  99.224  -39.444 1.00 35.33  ? 385  THR   D CA    1 
ATOM   6114  C  C     . THR   F 3 92  ? 10.211  100.749 -39.347 1.00 36.15  ? 385  THR   D C     1 
ATOM   6115  O  O     . THR   F 3 92  ? 11.230  101.301 -39.782 1.00 41.58  ? 385  THR   D O     1 
ATOM   6116  C  CB    . THR   F 3 92  ? 9.931   98.839  -40.915 1.00 31.70  ? 385  THR   D CB    1 
ATOM   6117  O  OG1   . THR   F 3 92  ? 8.652   99.288  -41.335 1.00 32.08  ? 385  THR   D OG1   1 
ATOM   6118  C  CG2   . THR   F 3 92  ? 10.018  97.351  -41.151 1.00 35.25  ? 385  THR   D CG2   1 
ATOM   6119  N  N     . THR   F 3 93  ? 9.189   101.451 -38.834 1.00 37.75  ? 386  THR   D N     1 
ATOM   6120  C  CA    . THR   F 3 93  ? 9.277   102.909 -38.747 1.00 36.90  ? 386  THR   D CA    1 
ATOM   6121  C  C     . THR   F 3 93  ? 8.975   103.399 -37.336 1.00 37.64  ? 386  THR   D C     1 
ATOM   6122  O  O     . THR   F 3 93  ? 8.239   102.753 -36.601 1.00 38.48  ? 386  THR   D O     1 
ATOM   6123  C  CB    . THR   F 3 93  ? 8.343   103.608 -39.739 1.00 34.97  ? 386  THR   D CB    1 
ATOM   6124  O  OG1   . THR   F 3 93  ? 7.003   103.305 -39.361 1.00 36.22  ? 386  THR   D OG1   1 
ATOM   6125  C  CG2   . THR   F 3 93  ? 8.560   103.173 -41.174 1.00 34.69  ? 386  THR   D CG2   1 
ATOM   6126  N  N     . PRO   F 3 94  ? 9.525   104.567 -36.930 1.00 41.03  ? 387  PRO   D N     1 
ATOM   6127  C  CA    . PRO   F 3 94  ? 9.133   105.211 -35.673 1.00 38.13  ? 387  PRO   D CA    1 
ATOM   6128  C  C     . PRO   F 3 94  ? 7.646   105.573 -35.583 1.00 40.12  ? 387  PRO   D C     1 
ATOM   6129  O  O     . PRO   F 3 94  ? 7.069   105.501 -34.502 1.00 40.12  ? 387  PRO   D O     1 
ATOM   6130  C  CB    . PRO   F 3 94  ? 9.958   106.504 -35.625 1.00 39.64  ? 387  PRO   D CB    1 
ATOM   6131  C  CG    . PRO   F 3 94  ? 11.060  106.318 -36.658 1.00 40.89  ? 387  PRO   D CG    1 
ATOM   6132  C  CD    . PRO   F 3 94  ? 10.523  105.349 -37.691 1.00 38.28  ? 387  PRO   D CD    1 
ATOM   6133  N  N     . GLU   F 3 95  ? 7.032   105.984 -36.703 1.00 43.51  ? 388  GLU   D N     1 
ATOM   6134  C  CA    . GLU   F 3 95  ? 5.606   106.292 -36.732 1.00 50.77  ? 388  GLU   D CA    1 
ATOM   6135  C  C     . GLU   F 3 95  ? 4.853   105.039 -36.296 1.00 45.12  ? 388  GLU   D C     1 
ATOM   6136  O  O     . GLU   F 3 95  ? 3.988   105.095 -35.432 1.00 54.62  ? 388  GLU   D O     1 
ATOM   6137  C  CB    . GLU   F 3 95  ? 5.058   106.689 -38.114 1.00 55.91  ? 388  GLU   D CB    1 
ATOM   6138  C  CG    . GLU   F 3 95  ? 5.888   107.704 -38.877 1.00 71.88  ? 388  GLU   D CG    1 
ATOM   6139  C  CD    . GLU   F 3 95  ? 6.975   107.155 -39.800 1.00 77.76  ? 388  GLU   D CD    1 
ATOM   6140  O  OE1   . GLU   F 3 95  ? 8.185   107.218 -39.418 1.00 66.07  ? 388  GLU   D OE1   1 
ATOM   6141  O  OE2   . GLU   F 3 95  ? 6.623   106.701 -40.919 1.00 84.91  ? 388  GLU   D OE2   1 
ATOM   6142  N  N     . GLY   F 3 96  ? 5.194   103.914 -36.930 1.00 40.57  ? 389  GLY   D N     1 
ATOM   6143  C  CA    . GLY   F 3 96  ? 4.503   102.651 -36.726 1.00 40.03  ? 389  GLY   D CA    1 
ATOM   6144  C  C     . GLY   F 3 96  ? 4.709   102.108 -35.316 1.00 37.32  ? 389  GLY   D C     1 
ATOM   6145  O  O     . GLY   F 3 96  ? 3.758   101.653 -34.702 1.00 41.33  ? 389  GLY   D O     1 
ATOM   6146  N  N     . VAL   F 3 97  ? 5.953   102.164 -34.826 1.00 34.72  ? 390  VAL   D N     1 
ATOM   6147  C  CA    . VAL   F 3 97  ? 6.316   101.675 -33.505 1.00 35.46  ? 390  VAL   D CA    1 
ATOM   6148  C  C     . VAL   F 3 97  ? 5.588   102.476 -32.415 1.00 38.82  ? 390  VAL   D C     1 
ATOM   6149  O  O     . VAL   F 3 97  ? 5.109   101.898 -31.443 1.00 37.86  ? 390  VAL   D O     1 
ATOM   6150  C  CB    . VAL   F 3 97  ? 7.844   101.717 -33.331 1.00 33.42  ? 390  VAL   D CB    1 
ATOM   6151  C  CG1   . VAL   F 3 97  ? 8.269   101.530 -31.885 1.00 34.53  ? 390  VAL   D CG1   1 
ATOM   6152  C  CG2   . VAL   F 3 97  ? 8.526   100.695 -34.227 1.00 34.82  ? 390  VAL   D CG2   1 
ATOM   6153  N  N     . ALA   F 3 98  ? 5.531   103.807 -32.562 1.00 40.80  ? 391  ALA   D N     1 
ATOM   6154  C  CA    . ALA   F 3 98  ? 4.831   104.669 -31.617 1.00 44.64  ? 391  ALA   D CA    1 
ATOM   6155  C  C     . ALA   F 3 98  ? 3.337   104.330 -31.593 1.00 46.31  ? 391  ALA   D C     1 
ATOM   6156  O  O     . ALA   F 3 98  ? 2.763   104.055 -30.537 1.00 44.90  ? 391  ALA   D O     1 
ATOM   6157  C  CB    . ALA   F 3 98  ? 5.065   106.117 -31.982 1.00 47.33  ? 391  ALA   D CB    1 
ATOM   6158  N  N     . ARG   F 3 99  ? 2.725   104.306 -32.778 1.00 44.48  ? 392  ARG   D N     1 
ATOM   6159  C  CA    . ARG   F 3 99  ? 1.322   103.952 -32.918 1.00 50.05  ? 392  ARG   D CA    1 
ATOM   6160  C  C     . ARG   F 3 99  ? 1.035   102.598 -32.275 1.00 49.03  ? 392  ARG   D C     1 
ATOM   6161  O  O     . ARG   F 3 99  ? 0.021   102.450 -31.591 1.00 45.81  ? 392  ARG   D O     1 
ATOM   6162  C  CB    . ARG   F 3 99  ? 0.929   103.937 -34.397 1.00 55.55  ? 392  ARG   D CB    1 
ATOM   6163  C  CG    . ARG   F 3 99  ? -0.565  104.039 -34.649 1.00 64.72  ? 392  ARG   D CG    1 
ATOM   6164  C  CD    . ARG   F 3 99  ? -0.795  103.939 -36.147 1.00 78.04  ? 392  ARG   D CD    1 
ATOM   6165  N  NE    . ARG   F 3 99  ? -2.062  104.516 -36.575 1.00 95.23  ? 392  ARG   D NE    1 
ATOM   6166  C  CZ    . ARG   F 3 99  ? -2.339  105.817 -36.620 1.00 102.35 ? 392  ARG   D CZ    1 
ATOM   6167  N  NH1   . ARG   F 3 99  ? -1.377  106.712 -36.452 1.00 101.20 ? 392  ARG   D NH1   1 
ATOM   6168  N  NH2   . ARG   F 3 99  ? -3.580  106.211 -36.863 1.00 98.82  ? 392  ARG   D NH2   1 
ATOM   6169  N  N     . ARG   F 3 100 ? 1.924   101.614 -32.487 1.00 45.83  ? 393  ARG   D N     1 
ATOM   6170  C  CA    . ARG   F 3 100 ? 1.653   100.255 -32.052 1.00 43.88  ? 393  ARG   D CA    1 
ATOM   6171  C  C     . ARG   F 3 100 ? 1.861   100.098 -30.548 1.00 42.83  ? 393  ARG   D C     1 
ATOM   6172  O  O     . ARG   F 3 100 ? 1.136   99.320  -29.920 1.00 47.42  ? 393  ARG   D O     1 
ATOM   6173  C  CB    . ARG   F 3 100 ? 2.501   99.241  -32.822 1.00 45.02  ? 393  ARG   D CB    1 
ATOM   6174  C  CG    . ARG   F 3 100 ? 2.355   97.822  -32.297 1.00 43.48  ? 393  ARG   D CG    1 
ATOM   6175  C  CD    . ARG   F 3 100 ? 2.231   96.719  -33.331 1.00 45.61  ? 393  ARG   D CD    1 
ATOM   6176  N  NE    . ARG   F 3 100 ? 3.430   95.955  -33.587 1.00 44.25  ? 393  ARG   D NE    1 
ATOM   6177  C  CZ    . ARG   F 3 100 ? 3.450   94.767  -34.185 1.00 45.12  ? 393  ARG   D CZ    1 
ATOM   6178  N  NH1   . ARG   F 3 100 ? 2.790   93.744  -33.675 1.00 40.41  ? 393  ARG   D NH1   1 
ATOM   6179  N  NH2   . ARG   F 3 100 ? 4.193   94.592  -35.266 1.00 44.76  ? 393  ARG   D NH2   1 
ATOM   6180  N  N     . TYR   F 3 101 ? 2.845   100.806 -29.974 1.00 39.79  ? 394  TYR   D N     1 
ATOM   6181  C  CA    . TYR   F 3 101 ? 3.302   100.504 -28.625 1.00 40.59  ? 394  TYR   D CA    1 
ATOM   6182  C  C     . TYR   F 3 101 ? 3.138   101.672 -27.649 1.00 46.67  ? 394  TYR   D C     1 
ATOM   6183  O  O     . TYR   F 3 101 ? 3.240   101.448 -26.442 1.00 45.53  ? 394  TYR   D O     1 
ATOM   6184  C  CB    . TYR   F 3 101 ? 4.772   100.073 -28.646 1.00 40.46  ? 394  TYR   D CB    1 
ATOM   6185  C  CG    . TYR   F 3 101 ? 5.012   98.793  -29.396 1.00 42.01  ? 394  TYR   D CG    1 
ATOM   6186  C  CD1   . TYR   F 3 101 ? 4.502   97.591  -28.934 1.00 39.53  ? 394  TYR   D CD1   1 
ATOM   6187  C  CD2   . TYR   F 3 101 ? 5.686   98.793  -30.604 1.00 42.89  ? 394  TYR   D CD2   1 
ATOM   6188  C  CE1   . TYR   F 3 101 ? 4.666   96.415  -29.646 1.00 40.86  ? 394  TYR   D CE1   1 
ATOM   6189  C  CE2   . TYR   F 3 101 ? 5.865   97.621  -31.322 1.00 43.19  ? 394  TYR   D CE2   1 
ATOM   6190  C  CZ    . TYR   F 3 101 ? 5.370   96.423  -30.836 1.00 41.14  ? 394  TYR   D CZ    1 
ATOM   6191  O  OH    . TYR   F 3 101 ? 5.554   95.264  -31.560 1.00 36.01  ? 394  TYR   D OH    1 
ATOM   6192  N  N     . GLY   F 3 102 ? 2.960   102.913 -28.135 1.00 49.63  ? 395  GLY   D N     1 
ATOM   6193  C  CA    . GLY   F 3 102 ? 2.673   104.024 -27.235 1.00 51.39  ? 395  GLY   D CA    1 
ATOM   6194  C  C     . GLY   F 3 102 ? 3.399   105.319 -27.595 1.00 56.63  ? 395  GLY   D C     1 
ATOM   6195  O  O     . GLY   F 3 102 ? 4.621   105.331 -27.769 1.00 58.56  ? 395  GLY   D O     1 
ATOM   6196  N  N     . GLY   F 3 103 ? 2.626   106.413 -27.627 1.00 52.22  ? 396  GLY   D N     1 
ATOM   6197  C  CA    . GLY   F 3 103 ? 3.133   107.735 -27.937 1.00 45.73  ? 396  GLY   D CA    1 
ATOM   6198  C  C     . GLY   F 3 103 ? 2.848   108.092 -29.390 1.00 48.71  ? 396  GLY   D C     1 
ATOM   6199  O  O     . GLY   F 3 103 ? 2.119   107.370 -30.078 1.00 42.95  ? 396  GLY   D O     1 
ATOM   6200  N  N     . GLU   F 3 104 ? 3.452   109.198 -29.848 1.00 51.61  ? 397  GLU   D N     1 
ATOM   6201  C  CA    . GLU   F 3 104 ? 3.258   109.676 -31.211 1.00 55.60  ? 397  GLU   D CA    1 
ATOM   6202  C  C     . GLU   F 3 104 ? 4.571   110.236 -31.778 1.00 52.46  ? 397  GLU   D C     1 
ATOM   6203  O  O     . GLU   F 3 104 ? 5.293   110.972 -31.096 1.00 46.02  ? 397  GLU   D O     1 
ATOM   6204  C  CB    . GLU   F 3 104 ? 2.151   110.732 -31.227 1.00 56.99  ? 397  GLU   D CB    1 
ATOM   6205  C  CG    . GLU   F 3 104 ? 1.572   110.978 -32.612 1.00 60.23  ? 397  GLU   D CG    1 
ATOM   6206  C  CD    . GLU   F 3 104 ? 0.744   112.247 -32.725 1.00 63.56  ? 397  GLU   D CD    1 
ATOM   6207  O  OE1   . GLU   F 3 104 ? 0.585   112.939 -31.694 1.00 62.40  ? 397  GLU   D OE1   1 
ATOM   6208  O  OE2   . GLU   F 3 104 ? 0.277   112.543 -33.849 1.00 63.49  ? 397  GLU   D OE2   1 
ATOM   6209  N  N     . TRP   F 3 105 ? 4.879   109.852 -33.024 1.00 47.42  ? 398  TRP   D N     1 
ATOM   6210  C  CA    . TRP   F 3 105 ? 6.026   110.386 -33.750 1.00 48.62  ? 398  TRP   D CA    1 
ATOM   6211  C  C     . TRP   F 3 105 ? 5.639   111.736 -34.335 1.00 49.49  ? 398  TRP   D C     1 
ATOM   6212  O  O     . TRP   F 3 105 ? 4.899   111.780 -35.324 1.00 48.30  ? 398  TRP   D O     1 
ATOM   6213  C  CB    . TRP   F 3 105 ? 6.458   109.429 -34.872 1.00 42.08  ? 398  TRP   D CB    1 
ATOM   6214  C  CG    . TRP   F 3 105 ? 7.621   109.863 -35.718 1.00 39.03  ? 398  TRP   D CG    1 
ATOM   6215  C  CD1   . TRP   F 3 105 ? 7.594   110.166 -37.055 1.00 35.79  ? 398  TRP   D CD1   1 
ATOM   6216  C  CD2   . TRP   F 3 105 ? 9.002   109.940 -35.316 1.00 34.84  ? 398  TRP   D CD2   1 
ATOM   6217  N  NE1   . TRP   F 3 105 ? 8.855   110.464 -37.497 1.00 36.66  ? 398  TRP   D NE1   1 
ATOM   6218  C  CE2   . TRP   F 3 105 ? 9.740   110.328 -36.453 1.00 36.92  ? 398  TRP   D CE2   1 
ATOM   6219  C  CE3   . TRP   F 3 105 ? 9.682   109.711 -34.116 1.00 37.55  ? 398  TRP   D CE3   1 
ATOM   6220  C  CZ2   . TRP   F 3 105 ? 11.124  110.498 -36.416 1.00 36.47  ? 398  TRP   D CZ2   1 
ATOM   6221  C  CZ3   . TRP   F 3 105 ? 11.046  109.899 -34.072 1.00 39.26  ? 398  TRP   D CZ3   1 
ATOM   6222  C  CH2   . TRP   F 3 105 ? 11.757  110.288 -35.212 1.00 37.86  ? 398  TRP   D CH2   1 
ATOM   6223  N  N     . THR   F 3 106 ? 6.153   112.815 -33.731 1.00 52.40  ? 399  THR   D N     1 
ATOM   6224  C  CA    . THR   F 3 106 ? 5.836   114.152 -34.212 1.00 55.62  ? 399  THR   D CA    1 
ATOM   6225  C  C     . THR   F 3 106 ? 7.019   114.678 -35.029 1.00 58.04  ? 399  THR   D C     1 
ATOM   6226  O  O     . THR   F 3 106 ? 7.924   113.913 -35.375 1.00 56.70  ? 399  THR   D O     1 
ATOM   6227  C  CB    . THR   F 3 106 ? 5.375   115.029 -33.041 1.00 49.39  ? 399  THR   D CB    1 
ATOM   6228  O  OG1   . THR   F 3 106 ? 6.453   115.168 -32.117 1.00 48.85  ? 399  THR   D OG1   1 
ATOM   6229  C  CG2   . THR   F 3 106 ? 4.172   114.449 -32.327 1.00 46.92  ? 399  THR   D CG2   1 
ATOM   6230  N  N     . GLU   F 3 107 ? 6.964   115.974 -35.377 1.00 54.93  ? 400  GLU   D N     1 
ATOM   6231  C  CA    . GLU   F 3 107 ? 8.001   116.623 -36.158 1.00 55.25  ? 400  GLU   D CA    1 
ATOM   6232  C  C     . GLU   F 3 107 ? 8.724   117.647 -35.291 1.00 53.35  ? 400  GLU   D C     1 
ATOM   6233  O  O     . GLU   F 3 107 ? 9.183   118.663 -35.807 1.00 61.65  ? 400  GLU   D O     1 
ATOM   6234  C  CB    . GLU   F 3 107 ? 7.420   117.299 -37.408 1.00 59.75  ? 400  GLU   D CB    1 
ATOM   6235  C  CG    . GLU   F 3 107 ? 6.647   116.365 -38.334 1.00 66.66  ? 400  GLU   D CG    1 
ATOM   6236  C  CD    . GLU   F 3 107 ? 7.460   115.254 -38.982 1.00 75.01  ? 400  GLU   D CD    1 
ATOM   6237  O  OE1   . GLU   F 3 107 ? 8.458   115.580 -39.665 1.00 76.64  ? 400  GLU   D OE1   1 
ATOM   6238  O  OE2   . GLU   F 3 107 ? 7.104   114.062 -38.787 1.00 81.08  ? 400  GLU   D OE2   1 
ATOM   6239  N  N     . GLU   F 3 108 ? 8.855   117.358 -33.990 1.00 48.22  ? 401  GLU   D N     1 
ATOM   6240  C  CA    . GLU   F 3 108 ? 9.451   118.294 -33.055 1.00 47.27  ? 401  GLU   D CA    1 
ATOM   6241  C  C     . GLU   F 3 108 ? 10.484  117.534 -32.228 1.00 47.47  ? 401  GLU   D C     1 
ATOM   6242  O  O     . GLU   F 3 108 ? 10.157  116.548 -31.574 1.00 52.89  ? 401  GLU   D O     1 
ATOM   6243  C  CB    . GLU   F 3 108 ? 8.348   118.951 -32.205 1.00 52.59  ? 401  GLU   D CB    1 
ATOM   6244  C  CG    . GLU   F 3 108 ? 8.765   120.224 -31.461 1.00 51.74  ? 401  GLU   D CG    1 
ATOM   6245  C  CD    . GLU   F 3 108 ? 9.561   120.006 -30.178 1.00 60.48  ? 401  GLU   D CD    1 
ATOM   6246  O  OE1   . GLU   F 3 108 ? 10.673  120.587 -30.049 1.00 62.91  ? 401  GLU   D OE1   1 
ATOM   6247  O  OE2   . GLU   F 3 108 ? 9.081   119.247 -29.298 1.00 66.65  ? 401  GLU   D OE2   1 
ATOM   6248  N  N     . ALA   F 3 109 ? 11.728  118.025 -32.250 1.00 49.24  ? 402  ALA   D N     1 
ATOM   6249  C  CA    . ALA   F 3 109 ? 12.855  117.360 -31.622 1.00 48.84  ? 402  ALA   D CA    1 
ATOM   6250  C  C     . ALA   F 3 109 ? 12.543  116.946 -30.186 1.00 46.84  ? 402  ALA   D C     1 
ATOM   6251  O  O     . ALA   F 3 109 ? 12.809  115.814 -29.806 1.00 47.31  ? 402  ALA   D O     1 
ATOM   6252  C  CB    . ALA   F 3 109 ? 14.078  118.250 -31.680 1.00 51.16  ? 402  ALA   D CB    1 
ATOM   6253  N  N     . GLY   F 3 110 ? 12.022  117.868 -29.373 1.00 51.02  ? 403  GLY   D N     1 
ATOM   6254  C  CA    . GLY   F 3 110 ? 11.811  117.609 -27.952 1.00 48.00  ? 403  GLY   D CA    1 
ATOM   6255  C  C     . GLY   F 3 110 ? 10.813  116.482 -27.677 1.00 43.69  ? 403  GLY   D C     1 
ATOM   6256  O  O     . GLY   F 3 110 ? 11.002  115.682 -26.768 1.00 46.28  ? 403  GLY   D O     1 
ATOM   6257  N  N     . GLU   F 3 111 ? 9.742   116.440 -28.462 1.00 44.40  ? 404  GLU   D N     1 
ATOM   6258  C  CA    . GLU   F 3 111 ? 8.765   115.370 -28.377 1.00 50.07  ? 404  GLU   D CA    1 
ATOM   6259  C  C     . GLU   F 3 111 ? 9.427   114.039 -28.748 1.00 53.08  ? 404  GLU   D C     1 
ATOM   6260  O  O     . GLU   F 3 111 ? 9.240   113.043 -28.052 1.00 49.46  ? 404  GLU   D O     1 
ATOM   6261  C  CB    . GLU   F 3 111 ? 7.569   115.722 -29.270 1.00 50.70  ? 404  GLU   D CB    1 
ATOM   6262  C  CG    . GLU   F 3 111 ? 6.717   116.847 -28.686 1.00 54.06  ? 404  GLU   D CG    1 
ATOM   6263  C  CD    . GLU   F 3 111 ? 5.577   117.383 -29.542 1.00 56.39  ? 404  GLU   D CD    1 
ATOM   6264  O  OE1   . GLU   F 3 111 ? 5.550   117.117 -30.753 1.00 55.16  ? 404  GLU   D OE1   1 
ATOM   6265  O  OE2   . GLU   F 3 111 ? 4.709   118.076 -28.983 1.00 69.41  ? 404  GLU   D OE2   1 
ATOM   6266  N  N     . ARG   F 3 112 ? 10.211  114.051 -29.841 1.00 48.81  ? 405  ARG   D N     1 
ATOM   6267  C  CA    . ARG   F 3 112 ? 10.913  112.876 -30.333 1.00 42.95  ? 405  ARG   D CA    1 
ATOM   6268  C  C     . ARG   F 3 112 ? 11.880  112.360 -29.275 1.00 43.65  ? 405  ARG   D C     1 
ATOM   6269  O  O     . ARG   F 3 112 ? 12.093  111.155 -29.170 1.00 44.59  ? 405  ARG   D O     1 
ATOM   6270  C  CB    . ARG   F 3 112 ? 11.672  113.175 -31.629 1.00 39.68  ? 405  ARG   D CB    1 
ATOM   6271  C  CG    . ARG   F 3 112 ? 10.772  113.335 -32.846 1.00 40.33  ? 405  ARG   D CG    1 
ATOM   6272  C  CD    . ARG   F 3 112 ? 11.571  113.642 -34.095 1.00 40.04  ? 405  ARG   D CD    1 
ATOM   6273  N  NE    . ARG   F 3 112 ? 10.734  113.769 -35.273 1.00 36.82  ? 405  ARG   D NE    1 
ATOM   6274  C  CZ    . ARG   F 3 112 ? 11.183  113.703 -36.522 1.00 38.48  ? 405  ARG   D CZ    1 
ATOM   6275  N  NH1   . ARG   F 3 112 ? 12.479  113.798 -36.783 1.00 34.86  ? 405  ARG   D NH1   1 
ATOM   6276  N  NH2   . ARG   F 3 112 ? 10.316  113.548 -37.508 1.00 41.70  ? 405  ARG   D NH2   1 
ATOM   6277  N  N     . ALA   F 3 113 ? 12.463  113.269 -28.489 1.00 42.59  ? 406  ALA   D N     1 
ATOM   6278  C  CA    . ALA   F 3 113 ? 13.438  112.863 -27.487 1.00 42.30  ? 406  ALA   D CA    1 
ATOM   6279  C  C     . ALA   F 3 113 ? 12.752  112.193 -26.299 1.00 43.63  ? 406  ALA   D C     1 
ATOM   6280  O  O     . ALA   F 3 113 ? 13.319  111.289 -25.688 1.00 42.66  ? 406  ALA   D O     1 
ATOM   6281  C  CB    . ALA   F 3 113 ? 14.259  114.045 -27.054 1.00 42.29  ? 406  ALA   D CB    1 
ATOM   6282  N  N     . ALA   F 3 114 ? 11.551  112.676 -25.952 1.00 47.28  ? 407  ALA   D N     1 
ATOM   6283  C  CA    . ALA   F 3 114 ? 10.787  112.135 -24.833 1.00 46.22  ? 407  ALA   D CA    1 
ATOM   6284  C  C     . ALA   F 3 114 ? 10.211  110.780 -25.228 1.00 43.00  ? 407  ALA   D C     1 
ATOM   6285  O  O     . ALA   F 3 114 ? 10.232  109.848 -24.433 1.00 49.42  ? 407  ALA   D O     1 
ATOM   6286  C  CB    . ALA   F 3 114 ? 9.699   113.099 -24.414 1.00 44.61  ? 407  ALA   D CB    1 
ATOM   6287  N  N     . LEU   F 3 115 ? 9.690   110.693 -26.458 1.00 42.75  ? 408  LEU   D N     1 
ATOM   6288  C  CA    . LEU   F 3 115 ? 9.205   109.444 -27.034 1.00 42.08  ? 408  LEU   D CA    1 
ATOM   6289  C  C     . LEU   F 3 115 ? 10.311  108.382 -27.012 1.00 43.31  ? 408  LEU   D C     1 
ATOM   6290  O  O     . LEU   F 3 115 ? 10.080  107.250 -26.596 1.00 45.72  ? 408  LEU   D O     1 
ATOM   6291  C  CB    . LEU   F 3 115 ? 8.704   109.744 -28.449 1.00 40.08  ? 408  LEU   D CB    1 
ATOM   6292  C  CG    . LEU   F 3 115 ? 8.154   108.554 -29.239 1.00 42.94  ? 408  LEU   D CG    1 
ATOM   6293  C  CD1   . LEU   F 3 115 ? 6.900   107.974 -28.591 1.00 37.71  ? 408  LEU   D CD1   1 
ATOM   6294  C  CD2   . LEU   F 3 115 ? 7.867   108.979 -30.680 1.00 39.71  ? 408  LEU   D CD2   1 
ATOM   6295  N  N     . SER   F 3 116 ? 11.531  108.769 -27.399 1.00 41.19  ? 409  SER   D N     1 
ATOM   6296  C  CA    . SER   F 3 116 ? 12.659  107.862 -27.396 1.00 40.01  ? 409  SER   D CA    1 
ATOM   6297  C  C     . SER   F 3 116 ? 12.818  107.239 -26.017 1.00 42.48  ? 409  SER   D C     1 
ATOM   6298  O  O     . SER   F 3 116 ? 12.994  106.028 -25.901 1.00 47.89  ? 409  SER   D O     1 
ATOM   6299  C  CB    . SER   F 3 116 ? 13.929  108.565 -27.839 1.00 40.87  ? 409  SER   D CB    1 
ATOM   6300  O  OG    . SER   F 3 116 ? 13.836  108.952 -29.201 1.00 38.07  ? 409  SER   D OG    1 
ATOM   6301  N  N     . GLU   F 3 117 ? 12.758  108.075 -24.974 1.00 44.75  ? 410  GLU   D N     1 
ATOM   6302  C  CA    . GLU   F 3 117 ? 12.943  107.603 -23.609 1.00 44.90  ? 410  GLU   D CA    1 
ATOM   6303  C  C     . GLU   F 3 117 ? 11.844  106.620 -23.191 1.00 41.93  ? 410  GLU   D C     1 
ATOM   6304  O  O     . GLU   F 3 117 ? 12.136  105.583 -22.592 1.00 40.39  ? 410  GLU   D O     1 
ATOM   6305  C  CB    . GLU   F 3 117 ? 12.965  108.783 -22.647 1.00 46.38  ? 410  GLU   D CB    1 
ATOM   6306  C  CG    . GLU   F 3 117 ? 13.164  108.370 -21.193 1.00 50.03  ? 410  GLU   D CG    1 
ATOM   6307  C  CD    . GLU   F 3 117 ? 13.297  109.560 -20.259 1.00 51.60  ? 410  GLU   D CD    1 
ATOM   6308  O  OE1   . GLU   F 3 117 ? 12.530  110.533 -20.440 1.00 47.21  ? 410  GLU   D OE1   1 
ATOM   6309  O  OE2   . GLU   F 3 117 ? 14.169  109.514 -19.374 1.00 47.25  ? 410  GLU   D OE2   1 
ATOM   6310  N  N     . ARG   F 3 118 ? 10.587  106.962 -23.491 1.00 43.81  ? 411  ARG   D N     1 
ATOM   6311  C  CA    . ARG   F 3 118 ? 9.442   106.166 -23.075 1.00 48.30  ? 411  ARG   D CA    1 
ATOM   6312  C  C     . ARG   F 3 118 ? 9.423   104.837 -23.835 1.00 46.27  ? 411  ARG   D C     1 
ATOM   6313  O  O     . ARG   F 3 118 ? 9.312   103.772 -23.218 1.00 45.86  ? 411  ARG   D O     1 
ATOM   6314  C  CB    . ARG   F 3 118 ? 8.128   106.932 -23.291 1.00 54.95  ? 411  ARG   D CB    1 
ATOM   6315  C  CG    . ARG   F 3 118 ? 7.931   108.150 -22.392 1.00 67.29  ? 411  ARG   D CG    1 
ATOM   6316  C  CD    . ARG   F 3 118 ? 6.461   108.473 -22.118 1.00 75.52  ? 411  ARG   D CD    1 
ATOM   6317  N  NE    . ARG   F 3 118 ? 5.908   107.564 -21.110 1.00 82.35  ? 411  ARG   D NE    1 
ATOM   6318  C  CZ    . ARG   F 3 118 ? 5.048   107.897 -20.147 1.00 77.96  ? 411  ARG   D CZ    1 
ATOM   6319  N  NH1   . ARG   F 3 118 ? 5.076   107.253 -18.995 1.00 69.33  ? 411  ARG   D NH1   1 
ATOM   6320  N  NH2   . ARG   F 3 118 ? 4.168   108.868 -20.334 1.00 77.59  ? 411  ARG   D NH2   1 
ATOM   6321  N  N     . LEU   F 3 119 ? 9.522   104.907 -25.173 1.00 42.40  ? 412  LEU   D N     1 
ATOM   6322  C  CA    . LEU   F 3 119 ? 9.562   103.713 -26.006 1.00 42.05  ? 412  LEU   D CA    1 
ATOM   6323  C  C     . LEU   F 3 119 ? 10.743  102.823 -25.621 1.00 40.29  ? 412  LEU   D C     1 
ATOM   6324  O  O     . LEU   F 3 119 ? 10.635  101.607 -25.710 1.00 40.11  ? 412  LEU   D O     1 
ATOM   6325  C  CB    . LEU   F 3 119 ? 9.639   104.101 -27.483 1.00 43.05  ? 412  LEU   D CB    1 
ATOM   6326  C  CG    . LEU   F 3 119 ? 8.312   104.430 -28.163 1.00 41.82  ? 412  LEU   D CG    1 
ATOM   6327  C  CD1   . LEU   F 3 119 ? 8.537   104.729 -29.636 1.00 41.14  ? 412  LEU   D CD1   1 
ATOM   6328  C  CD2   . LEU   F 3 119 ? 7.305   103.286 -28.008 1.00 44.88  ? 412  LEU   D CD2   1 
ATOM   6329  N  N     . PHE   F 3 120 ? 11.846  103.396 -25.137 1.00 38.32  ? 413  PHE   D N     1 
ATOM   6330  C  CA    . PHE   F 3 120 ? 12.966  102.538 -24.780 1.00 40.33  ? 413  PHE   D CA    1 
ATOM   6331  C  C     . PHE   F 3 120 ? 12.599  101.597 -23.645 1.00 41.74  ? 413  PHE   D C     1 
ATOM   6332  O  O     . PHE   F 3 120 ? 12.850  100.399 -23.757 1.00 43.83  ? 413  PHE   D O     1 
ATOM   6333  C  CB    . PHE   F 3 120 ? 14.229  103.287 -24.343 1.00 43.18  ? 413  PHE   D CB    1 
ATOM   6334  C  CG    . PHE   F 3 120 ? 15.397  102.355 -24.100 1.00 42.04  ? 413  PHE   D CG    1 
ATOM   6335  C  CD1   . PHE   F 3 120 ? 15.993  101.672 -25.151 1.00 42.86  ? 413  PHE   D CD1   1 
ATOM   6336  C  CD2   . PHE   F 3 120 ? 15.855  102.102 -22.816 1.00 46.30  ? 413  PHE   D CD2   1 
ATOM   6337  C  CE1   . PHE   F 3 120 ? 17.056  100.806 -24.929 1.00 47.88  ? 413  PHE   D CE1   1 
ATOM   6338  C  CE2   . PHE   F 3 120 ? 16.911  101.225 -22.587 1.00 46.60  ? 413  PHE   D CE2   1 
ATOM   6339  C  CZ    . PHE   F 3 120 ? 17.507  100.575 -23.644 1.00 47.49  ? 413  PHE   D CZ    1 
ATOM   6340  N  N     . ALA   F 3 121 ? 12.088  102.154 -22.527 1.00 44.62  ? 414  ALA   D N     1 
ATOM   6341  C  CA    . ALA   F 3 121 ? 11.743  101.352 -21.350 1.00 39.99  ? 414  ALA   D CA    1 
ATOM   6342  C  C     . ALA   F 3 121 ? 10.545  100.441 -21.632 1.00 35.93  ? 414  ALA   D C     1 
ATOM   6343  O  O     . ALA   F 3 121 ? 10.479  99.337  -21.121 1.00 42.33  ? 414  ALA   D O     1 
ATOM   6344  C  CB    . ALA   F 3 121 ? 11.450  102.249 -20.176 1.00 40.47  ? 414  ALA   D CB    1 
ATOM   6345  N  N     . ASN   F 3 122 ? 9.587   100.942 -22.415 1.00 34.80  ? 415  ASN   D N     1 
ATOM   6346  C  CA    . ASN   F 3 122 ? 8.384   100.222 -22.801 1.00 36.56  ? 415  ASN   D CA    1 
ATOM   6347  C  C     . ASN   F 3 122 ? 8.747   98.936  -23.561 1.00 40.95  ? 415  ASN   D C     1 
ATOM   6348  O  O     . ASN   F 3 122 ? 8.315   97.843  -23.172 1.00 42.30  ? 415  ASN   D O     1 
ATOM   6349  C  CB    . ASN   F 3 122 ? 7.470   101.182 -23.563 1.00 38.00  ? 415  ASN   D CB    1 
ATOM   6350  C  CG    . ASN   F 3 122 ? 6.269   100.536 -24.215 1.00 43.44  ? 415  ASN   D CG    1 
ATOM   6351  O  OD1   . ASN   F 3 122 ? 6.258   99.332  -24.468 1.00 54.90  ? 415  ASN   D OD1   1 
ATOM   6352  N  ND2   . ASN   F 3 122 ? 5.272   101.339 -24.551 1.00 42.88  ? 415  ASN   D ND2   1 
ATOM   6353  N  N     . LEU   F 3 123 ? 9.584   99.062  -24.609 1.00 39.44  ? 416  LEU   D N     1 
ATOM   6354  C  CA    . LEU   F 3 123 ? 9.995   97.942  -25.451 1.00 36.92  ? 416  LEU   D CA    1 
ATOM   6355  C  C     . LEU   F 3 123 ? 10.965  97.021  -24.727 1.00 35.51  ? 416  LEU   D C     1 
ATOM   6356  O  O     . LEU   F 3 123 ? 10.894  95.813  -24.901 1.00 38.50  ? 416  LEU   D O     1 
ATOM   6357  C  CB    . LEU   F 3 123 ? 10.608  98.484  -26.745 1.00 35.86  ? 416  LEU   D CB    1 
ATOM   6358  C  CG    . LEU   F 3 123 ? 9.578   99.113  -27.679 1.00 37.40  ? 416  LEU   D CG    1 
ATOM   6359  C  CD1   . LEU   F 3 123 ? 10.250  99.928  -28.766 1.00 41.73  ? 416  LEU   D CD1   1 
ATOM   6360  C  CD2   . LEU   F 3 123 ? 8.682   98.045  -28.285 1.00 39.24  ? 416  LEU   D CD2   1 
ATOM   6361  N  N     . TRP   F 3 124 ? 11.872  97.589  -23.934 1.00 38.33  ? 417  TRP   D N     1 
ATOM   6362  C  CA    . TRP   F 3 124 ? 12.710  96.796  -23.053 1.00 39.34  ? 417  TRP   D CA    1 
ATOM   6363  C  C     . TRP   F 3 124 ? 11.832  95.887  -22.192 1.00 39.26  ? 417  TRP   D C     1 
ATOM   6364  O  O     . TRP   F 3 124 ? 12.028  94.674  -22.162 1.00 42.85  ? 417  TRP   D O     1 
ATOM   6365  C  CB    . TRP   F 3 124 ? 13.610  97.701  -22.194 1.00 43.53  ? 417  TRP   D CB    1 
ATOM   6366  C  CG    . TRP   F 3 124 ? 14.678  96.936  -21.474 1.00 47.64  ? 417  TRP   D CG    1 
ATOM   6367  C  CD1   . TRP   F 3 124 ? 14.625  96.465  -20.191 1.00 52.35  ? 417  TRP   D CD1   1 
ATOM   6368  C  CD2   . TRP   F 3 124 ? 15.941  96.503  -22.008 1.00 49.15  ? 417  TRP   D CD2   1 
ATOM   6369  N  NE1   . TRP   F 3 124 ? 15.770  95.780  -19.886 1.00 55.50  ? 417  TRP   D NE1   1 
ATOM   6370  C  CE2   . TRP   F 3 124 ? 16.600  95.792  -20.978 1.00 53.92  ? 417  TRP   D CE2   1 
ATOM   6371  C  CE3   . TRP   F 3 124 ? 16.595  96.666  -23.238 1.00 50.98  ? 417  TRP   D CE3   1 
ATOM   6372  C  CZ2   . TRP   F 3 124 ? 17.870  95.241  -21.151 1.00 50.33  ? 417  TRP   D CZ2   1 
ATOM   6373  C  CZ3   . TRP   F 3 124 ? 17.855  96.127  -23.406 1.00 49.97  ? 417  TRP   D CZ3   1 
ATOM   6374  C  CH2   . TRP   F 3 124 ? 18.478  95.414  -22.376 1.00 51.66  ? 417  TRP   D CH2   1 
ATOM   6375  N  N     . GLY   F 3 125 ? 10.842  96.486  -21.512 1.00 40.83  ? 418  GLY   D N     1 
ATOM   6376  C  CA    . GLY   F 3 125 ? 9.880   95.746  -20.707 1.00 35.54  ? 418  GLY   D CA    1 
ATOM   6377  C  C     . GLY   F 3 125 ? 9.198   94.623  -21.490 1.00 35.70  ? 418  GLY   D C     1 
ATOM   6378  O  O     . GLY   F 3 125 ? 9.050   93.512  -20.994 1.00 38.90  ? 418  GLY   D O     1 
ATOM   6379  N  N     . ARG   F 3 126 ? 8.771   94.905  -22.727 1.00 37.94  ? 419  ARG   D N     1 
ATOM   6380  C  CA    . ARG   F 3 126 ? 8.076   93.909  -23.535 1.00 36.65  ? 419  ARG   D CA    1 
ATOM   6381  C  C     . ARG   F 3 126 ? 9.014   92.782  -23.966 1.00 36.06  ? 419  ARG   D C     1 
ATOM   6382  O  O     . ARG   F 3 126 ? 8.566   91.720  -24.377 1.00 33.92  ? 419  ARG   D O     1 
ATOM   6383  C  CB    . ARG   F 3 126 ? 7.462   94.580  -24.758 1.00 35.77  ? 419  ARG   D CB    1 
ATOM   6384  C  CG    . ARG   F 3 126 ? 6.311   95.488  -24.395 1.00 37.64  ? 419  ARG   D CG    1 
ATOM   6385  C  CD    . ARG   F 3 126 ? 5.798   96.244  -25.590 1.00 43.08  ? 419  ARG   D CD    1 
ATOM   6386  N  NE    . ARG   F 3 126 ? 4.722   97.128  -25.171 1.00 43.17  ? 419  ARG   D NE    1 
ATOM   6387  C  CZ    . ARG   F 3 126 ? 3.440   96.873  -25.363 1.00 39.54  ? 419  ARG   D CZ    1 
ATOM   6388  N  NH1   . ARG   F 3 126 ? 3.060   95.655  -25.705 1.00 39.65  ? 419  ARG   D NH1   1 
ATOM   6389  N  NH2   . ARG   F 3 126 ? 2.566   97.855  -25.239 1.00 39.78  ? 419  ARG   D NH2   1 
ATOM   6390  N  N     . LEU   F 3 127 ? 10.321  93.021  -23.878 1.00 37.88  ? 420  LEU   D N     1 
ATOM   6391  C  CA    . LEU   F 3 127 ? 11.302  92.035  -24.285 1.00 40.00  ? 420  LEU   D CA    1 
ATOM   6392  C  C     . LEU   F 3 127 ? 11.820  91.253  -23.081 1.00 42.19  ? 420  LEU   D C     1 
ATOM   6393  O  O     . LEU   F 3 127 ? 12.732  90.448  -23.231 1.00 42.23  ? 420  LEU   D O     1 
ATOM   6394  C  CB    . LEU   F 3 127 ? 12.438  92.776  -24.996 1.00 41.63  ? 420  LEU   D CB    1 
ATOM   6395  C  CG    . LEU   F 3 127 ? 12.293  92.927  -26.506 1.00 39.06  ? 420  LEU   D CG    1 
ATOM   6396  C  CD1   . LEU   F 3 127 ? 13.342  93.884  -27.027 1.00 40.78  ? 420  LEU   D CD1   1 
ATOM   6397  C  CD2   . LEU   F 3 127 ? 12.427  91.583  -27.199 1.00 42.94  ? 420  LEU   D CD2   1 
ATOM   6398  N  N     . GLU   F 3 128 ? 11.259  91.480  -21.887 1.00 49.59  ? 421  GLU   D N     1 
ATOM   6399  C  CA    . GLU   F 3 128 ? 11.721  90.749  -20.714 1.00 52.92  ? 421  GLU   D CA    1 
ATOM   6400  C  C     . GLU   F 3 128 ? 11.450  89.256  -20.895 1.00 46.44  ? 421  GLU   D C     1 
ATOM   6401  O  O     . GLU   F 3 128 ? 10.404  88.849  -21.414 1.00 41.15  ? 421  GLU   D O     1 
ATOM   6402  C  CB    . GLU   F 3 128 ? 11.088  91.296  -19.438 1.00 60.65  ? 421  GLU   D CB    1 
ATOM   6403  C  CG    . GLU   F 3 128 ? 11.769  92.582  -19.002 1.00 73.99  ? 421  GLU   D CG    1 
ATOM   6404  C  CD    . GLU   F 3 128 ? 11.298  93.168  -17.681 1.00 78.74  ? 421  GLU   D CD    1 
ATOM   6405  O  OE1   . GLU   F 3 128 ? 10.558  92.463  -16.950 1.00 75.01  ? 421  GLU   D OE1   1 
ATOM   6406  O  OE2   . GLU   F 3 128 ? 11.669  94.334  -17.402 1.00 70.38  ? 421  GLU   D OE2   1 
ATOM   6407  N  N     . GLY   F 3 129 ? 12.447  88.449  -20.523 1.00 41.08  ? 422  GLY   D N     1 
ATOM   6408  C  CA    . GLY   F 3 129 ? 12.354  87.007  -20.694 1.00 41.52  ? 422  GLY   D CA    1 
ATOM   6409  C  C     . GLY   F 3 129 ? 12.810  86.518  -22.072 1.00 40.83  ? 422  GLY   D C     1 
ATOM   6410  O  O     . GLY   F 3 129 ? 12.985  85.316  -22.242 1.00 36.10  ? 422  GLY   D O     1 
ATOM   6411  N  N     . GLU   F 3 130 ? 12.975  87.440  -23.045 1.00 40.12  ? 423  GLU   D N     1 
ATOM   6412  C  CA    . GLU   F 3 130 ? 13.382  87.098  -24.400 1.00 37.81  ? 423  GLU   D CA    1 
ATOM   6413  C  C     . GLU   F 3 130 ? 14.901  87.241  -24.492 1.00 34.97  ? 423  GLU   D C     1 
ATOM   6414  O  O     . GLU   F 3 130 ? 15.421  88.136  -25.146 1.00 34.45  ? 423  GLU   D O     1 
ATOM   6415  C  CB    . GLU   F 3 130 ? 12.660  87.988  -25.423 1.00 40.28  ? 423  GLU   D CB    1 
ATOM   6416  C  CG    . GLU   F 3 130 ? 11.158  87.734  -25.534 1.00 39.78  ? 423  GLU   D CG    1 
ATOM   6417  C  CD    . GLU   F 3 130 ? 10.789  86.372  -26.101 1.00 43.28  ? 423  GLU   D CD    1 
ATOM   6418  O  OE1   . GLU   F 3 130 ? 11.710  85.590  -26.463 1.00 43.91  ? 423  GLU   D OE1   1 
ATOM   6419  O  OE2   . GLU   F 3 130 ? 9.584   86.104  -26.232 1.00 47.92  ? 423  GLU   D OE2   1 
ATOM   6420  N  N     . GLU   F 3 131 ? 15.606  86.324  -23.841 1.00 33.09  ? 424  GLU   D N     1 
ATOM   6421  C  CA    . GLU   F 3 131 ? 17.021  86.483  -23.591 1.00 36.05  ? 424  GLU   D CA    1 
ATOM   6422  C  C     . GLU   F 3 131 ? 17.865  86.423  -24.873 1.00 35.42  ? 424  GLU   D C     1 
ATOM   6423  O  O     . GLU   F 3 131 ? 18.893  87.109  -24.964 1.00 35.57  ? 424  GLU   D O     1 
ATOM   6424  C  CB    . GLU   F 3 131 ? 17.433  85.433  -22.562 1.00 43.02  ? 424  GLU   D CB    1 
ATOM   6425  C  CG    . GLU   F 3 131 ? 18.848  85.646  -22.079 1.00 50.93  ? 424  GLU   D CG    1 
ATOM   6426  C  CD    . GLU   F 3 131 ? 19.075  87.092  -21.662 1.00 59.39  ? 424  GLU   D CD    1 
ATOM   6427  O  OE1   . GLU   F 3 131 ? 18.264  87.551  -20.769 1.00 52.13  ? 424  GLU   D OE1   1 
ATOM   6428  O  OE2   . GLU   F 3 131 ? 19.995  87.769  -22.284 1.00 43.25  ? 424  GLU   D OE2   1 
ATOM   6429  N  N     . ARG   F 3 132 ? 17.448  85.626  -25.876 1.00 33.71  ? 425  ARG   D N     1 
ATOM   6430  C  CA    . ARG   F 3 132 ? 18.211  85.539  -27.122 1.00 33.38  ? 425  ARG   D CA    1 
ATOM   6431  C  C     . ARG   F 3 132 ? 17.989  86.788  -27.981 1.00 30.41  ? 425  ARG   D C     1 
ATOM   6432  O  O     . ARG   F 3 132 ? 18.929  87.273  -28.599 1.00 29.26  ? 425  ARG   D O     1 
ATOM   6433  C  CB    . ARG   F 3 132 ? 17.921  84.239  -27.883 1.00 33.14  ? 425  ARG   D CB    1 
ATOM   6434  C  CG    . ARG   F 3 132 ? 18.310  82.966  -27.125 1.00 33.92  ? 425  ARG   D CG    1 
ATOM   6435  C  CD    . ARG   F 3 132 ? 18.558  81.771  -28.025 1.00 33.58  ? 425  ARG   D CD    1 
ATOM   6436  N  NE    . ARG   F 3 132 ? 17.337  81.329  -28.694 1.00 34.78  ? 425  ARG   D NE    1 
ATOM   6437  C  CZ    . ARG   F 3 132 ? 17.301  80.567  -29.786 1.00 34.53  ? 425  ARG   D CZ    1 
ATOM   6438  N  NH1   . ARG   F 3 132 ? 18.425  80.190  -30.368 1.00 31.95  ? 425  ARG   D NH1   1 
ATOM   6439  N  NH2   . ARG   F 3 132 ? 16.141  80.232  -30.323 1.00 34.87  ? 425  ARG   D NH2   1 
ATOM   6440  N  N     . LEU   F 3 133 ? 16.770  87.343  -27.986 1.00 30.67  ? 426  LEU   D N     1 
ATOM   6441  C  CA    . LEU   F 3 133 ? 16.527  88.624  -28.648 1.00 30.07  ? 426  LEU   D CA    1 
ATOM   6442  C  C     . LEU   F 3 133 ? 17.337  89.741  -27.990 1.00 27.89  ? 426  LEU   D C     1 
ATOM   6443  O  O     . LEU   F 3 133 ? 17.903  90.591  -28.671 1.00 28.48  ? 426  LEU   D O     1 
ATOM   6444  C  CB    . LEU   F 3 133 ? 15.039  88.980  -28.614 1.00 30.28  ? 426  LEU   D CB    1 
ATOM   6445  C  CG    . LEU   F 3 133 ? 14.102  88.081  -29.414 1.00 30.80  ? 426  LEU   D CG    1 
ATOM   6446  C  CD1   . LEU   F 3 133 ? 12.692  88.648  -29.384 1.00 31.98  ? 426  LEU   D CD1   1 
ATOM   6447  C  CD2   . LEU   F 3 133 ? 14.560  87.932  -30.848 1.00 33.45  ? 426  LEU   D CD2   1 
ATOM   6448  N  N     . LEU   F 3 134 ? 17.433  89.734  -26.662 1.00 30.32  ? 427  LEU   D N     1 
ATOM   6449  C  CA    . LEU   F 3 134 ? 18.215  90.757  -25.966 1.00 33.11  ? 427  LEU   D CA    1 
ATOM   6450  C  C     . LEU   F 3 134 ? 19.719  90.609  -26.239 1.00 30.14  ? 427  LEU   D C     1 
ATOM   6451  O  O     . LEU   F 3 134 ? 20.428  91.606  -26.325 1.00 34.56  ? 427  LEU   D O     1 
ATOM   6452  C  CB    . LEU   F 3 134 ? 17.911  90.684  -24.461 1.00 35.85  ? 427  LEU   D CB    1 
ATOM   6453  C  CG    . LEU   F 3 134 ? 16.557  91.245  -24.036 1.00 38.07  ? 427  LEU   D CG    1 
ATOM   6454  C  CD1   . LEU   F 3 134 ? 16.305  91.002  -22.552 1.00 37.32  ? 427  LEU   D CD1   1 
ATOM   6455  C  CD2   . LEU   F 3 134 ? 16.475  92.727  -24.357 1.00 41.73  ? 427  LEU   D CD2   1 
ATOM   6456  N  N     . TRP   F 3 135 ? 20.210  89.372  -26.355 1.00 29.99  ? 428  TRP   D N     1 
ATOM   6457  C  CA    . TRP   F 3 135 ? 21.589  89.108  -26.759 1.00 29.54  ? 428  TRP   D CA    1 
ATOM   6458  C  C     . TRP   F 3 135 ? 21.853  89.652  -28.174 1.00 27.67  ? 428  TRP   D C     1 
ATOM   6459  O  O     . TRP   F 3 135 ? 22.906  90.225  -28.455 1.00 28.16  ? 428  TRP   D O     1 
ATOM   6460  C  CB    . TRP   F 3 135 ? 21.907  87.596  -26.644 1.00 28.53  ? 428  TRP   D CB    1 
ATOM   6461  C  CG    . TRP   F 3 135 ? 23.351  87.264  -26.886 1.00 30.30  ? 428  TRP   D CG    1 
ATOM   6462  C  CD1   . TRP   F 3 135 ? 24.308  87.064  -25.933 1.00 31.77  ? 428  TRP   D CD1   1 
ATOM   6463  C  CD2   . TRP   F 3 135 ? 24.024  87.100  -28.154 1.00 30.34  ? 428  TRP   D CD2   1 
ATOM   6464  N  NE1   . TRP   F 3 135 ? 25.525  86.806  -26.507 1.00 32.03  ? 428  TRP   D NE1   1 
ATOM   6465  C  CE2   . TRP   F 3 135 ? 25.385  86.822  -27.871 1.00 33.51  ? 428  TRP   D CE2   1 
ATOM   6466  C  CE3   . TRP   F 3 135 ? 23.619  87.123  -29.495 1.00 29.26  ? 428  TRP   D CE3   1 
ATOM   6467  C  CZ2   . TRP   F 3 135 ? 26.334  86.608  -28.876 1.00 30.49  ? 428  TRP   D CZ2   1 
ATOM   6468  C  CZ3   . TRP   F 3 135 ? 24.557  86.910  -30.486 1.00 30.07  ? 428  TRP   D CZ3   1 
ATOM   6469  C  CH2   . TRP   F 3 135 ? 25.897  86.668  -30.181 1.00 30.25  ? 428  TRP   D CH2   1 
ATOM   6470  N  N     . LEU   F 3 136 ? 20.905  89.463  -29.097 1.00 29.56  ? 429  LEU   D N     1 
ATOM   6471  C  CA    . LEU   F 3 136 ? 21.063  89.995  -30.448 1.00 28.37  ? 429  LEU   D CA    1 
ATOM   6472  C  C     . LEU   F 3 136 ? 21.145  91.509  -30.398 1.00 28.28  ? 429  LEU   D C     1 
ATOM   6473  O  O     . LEU   F 3 136 ? 21.914  92.100  -31.137 1.00 31.26  ? 429  LEU   D O     1 
ATOM   6474  C  CB    . LEU   F 3 136 ? 19.893  89.568  -31.326 1.00 27.52  ? 429  LEU   D CB    1 
ATOM   6475  C  CG    . LEU   F 3 136 ? 19.964  88.137  -31.830 1.00 29.47  ? 429  LEU   D CG    1 
ATOM   6476  C  CD1   . LEU   F 3 136 ? 18.666  87.758  -32.498 1.00 32.41  ? 429  LEU   D CD1   1 
ATOM   6477  C  CD2   . LEU   F 3 136 ? 21.117  87.962  -32.804 1.00 32.23  ? 429  LEU   D CD2   1 
ATOM   6478  N  N     . TYR   F 3 137 ? 20.320  92.117  -29.542 1.00 30.36  ? 430  TYR   D N     1 
ATOM   6479  C  CA    . TYR   F 3 137 ? 20.329  93.550  -29.360 1.00 29.98  ? 430  TYR   D CA    1 
ATOM   6480  C  C     . TYR   F 3 137 ? 21.711  93.996  -28.890 1.00 32.14  ? 430  TYR   D C     1 
ATOM   6481  O  O     . TYR   F 3 137 ? 22.349  94.863  -29.495 1.00 32.97  ? 430  TYR   D O     1 
ATOM   6482  C  CB    . TYR   F 3 137 ? 19.242  93.982  -28.366 1.00 30.62  ? 430  TYR   D CB    1 
ATOM   6483  C  CG    . TYR   F 3 137 ? 19.220  95.477  -28.156 1.00 31.56  ? 430  TYR   D CG    1 
ATOM   6484  C  CD1   . TYR   F 3 137 ? 18.793  96.332  -29.162 1.00 28.50  ? 430  TYR   D CD1   1 
ATOM   6485  C  CD2   . TYR   F 3 137 ? 19.746  96.045  -27.007 1.00 32.11  ? 430  TYR   D CD2   1 
ATOM   6486  C  CE1   . TYR   F 3 137 ? 18.805  97.707  -28.991 1.00 28.48  ? 430  TYR   D CE1   1 
ATOM   6487  C  CE2   . TYR   F 3 137 ? 19.771  97.419  -26.821 1.00 29.40  ? 430  TYR   D CE2   1 
ATOM   6488  C  CZ    . TYR   F 3 137 ? 19.304  98.250  -27.820 1.00 28.45  ? 430  TYR   D CZ    1 
ATOM   6489  O  OH    . TYR   F 3 137 ? 19.356  99.608  -27.646 1.00 28.44  ? 430  TYR   D OH    1 
ATOM   6490  N  N     . ARG   F 3 138 ? 22.170  93.424  -27.778 1.00 35.72  ? 431  ARG   D N     1 
ATOM   6491  C  CA    . ARG   F 3 138 ? 23.366  93.934  -27.116 1.00 35.31  ? 431  ARG   D CA    1 
ATOM   6492  C  C     . ARG   F 3 138 ? 24.615  93.589  -27.919 1.00 32.86  ? 431  ARG   D C     1 
ATOM   6493  O  O     . ARG   F 3 138 ? 25.541  94.400  -27.999 1.00 30.97  ? 431  ARG   D O     1 
ATOM   6494  C  CB    . ARG   F 3 138 ? 23.523  93.340  -25.713 1.00 39.30  ? 431  ARG   D CB    1 
ATOM   6495  C  CG    . ARG   F 3 138 ? 22.520  93.841  -24.684 1.00 43.37  ? 431  ARG   D CG    1 
ATOM   6496  C  CD    . ARG   F 3 138 ? 22.978  93.470  -23.272 1.00 47.23  ? 431  ARG   D CD    1 
ATOM   6497  N  NE    . ARG   F 3 138 ? 22.133  92.516  -22.568 1.00 48.91  ? 431  ARG   D NE    1 
ATOM   6498  C  CZ    . ARG   F 3 138 ? 22.074  91.213  -22.813 1.00 52.45  ? 431  ARG   D CZ    1 
ATOM   6499  N  NH1   . ARG   F 3 138 ? 20.928  90.586  -22.640 1.00 51.70  ? 431  ARG   D NH1   1 
ATOM   6500  N  NH2   . ARG   F 3 138 ? 23.136  90.546  -23.238 1.00 51.31  ? 431  ARG   D NH2   1 
ATOM   6501  N  N     . GLU   F 3 139 ? 24.668  92.355  -28.449 1.00 31.75  ? 432  GLU   D N     1 
ATOM   6502  C  CA    . GLU   F 3 139 ? 25.902  91.845  -29.017 1.00 32.81  ? 432  GLU   D CA    1 
ATOM   6503  C  C     . GLU   F 3 139 ? 25.949  91.981  -30.536 1.00 35.01  ? 432  GLU   D C     1 
ATOM   6504  O  O     . GLU   F 3 139 ? 27.020  91.817  -31.106 1.00 38.46  ? 432  GLU   D O     1 
ATOM   6505  C  CB    . GLU   F 3 139 ? 26.105  90.383  -28.630 1.00 34.83  ? 432  GLU   D CB    1 
ATOM   6506  C  CG    . GLU   F 3 139 ? 26.183  90.171  -27.134 1.00 35.25  ? 432  GLU   D CG    1 
ATOM   6507  C  CD    . GLU   F 3 139 ? 27.331  90.877  -26.438 1.00 36.25  ? 432  GLU   D CD    1 
ATOM   6508  O  OE1   . GLU   F 3 139 ? 28.369  91.141  -27.092 1.00 43.44  ? 432  GLU   D OE1   1 
ATOM   6509  O  OE2   . GLU   F 3 139 ? 27.182  91.175  -25.256 1.00 36.91  ? 432  GLU   D OE2   1 
ATOM   6510  N  N     . VAL   F 3 140 ? 24.816  92.252  -31.202 1.00 34.59  ? 433  VAL   D N     1 
ATOM   6511  C  CA    . VAL   F 3 140 ? 24.833  92.346  -32.656 1.00 30.46  ? 433  VAL   D CA    1 
ATOM   6512  C  C     . VAL   F 3 140 ? 24.262  93.684  -33.125 1.00 30.84  ? 433  VAL   D C     1 
ATOM   6513  O  O     . VAL   F 3 140 ? 24.988  94.462  -33.747 1.00 34.62  ? 433  VAL   D O     1 
ATOM   6514  C  CB    . VAL   F 3 140 ? 24.127  91.151  -33.312 1.00 28.23  ? 433  VAL   D CB    1 
ATOM   6515  C  CG1   . VAL   F 3 140 ? 24.055  91.305  -34.816 1.00 28.70  ? 433  VAL   D CG1   1 
ATOM   6516  C  CG2   . VAL   F 3 140 ? 24.811  89.846  -32.947 1.00 27.92  ? 433  VAL   D CG2   1 
ATOM   6517  N  N     . GLU   F 3 141 ? 22.987  93.968  -32.826 1.00 29.94  ? 434  GLU   D N     1 
ATOM   6518  C  CA    . GLU   F 3 141 ? 22.293  95.062  -33.493 1.00 30.00  ? 434  GLU   D CA    1 
ATOM   6519  C  C     . GLU   F 3 141 ? 22.811  96.421  -33.030 1.00 30.32  ? 434  GLU   D C     1 
ATOM   6520  O  O     . GLU   F 3 141 ? 23.083  97.294  -33.850 1.00 31.84  ? 434  GLU   D O     1 
ATOM   6521  C  CB    . GLU   F 3 141 ? 20.779  94.965  -33.305 1.00 29.89  ? 434  GLU   D CB    1 
ATOM   6522  C  CG    . GLU   F 3 141 ? 20.144  93.778  -34.028 1.00 30.20  ? 434  GLU   D CG    1 
ATOM   6523  C  CD    . GLU   F 3 141 ? 20.228  93.724  -35.551 1.00 32.96  ? 434  GLU   D CD    1 
ATOM   6524  O  OE1   . GLU   F 3 141 ? 20.766  94.683  -36.178 1.00 31.56  ? 434  GLU   D OE1   1 
ATOM   6525  O  OE2   . GLU   F 3 141 ? 19.712  92.724  -36.123 1.00 31.37  ? 434  GLU   D OE2   1 
ATOM   6526  N  N     . ARG   F 3 142 ? 22.958  96.601  -31.721 1.00 32.53  ? 435  ARG   D N     1 
ATOM   6527  C  CA    . ARG   F 3 142 ? 23.390  97.885  -31.194 1.00 33.25  ? 435  ARG   D CA    1 
ATOM   6528  C  C     . ARG   F 3 142 ? 24.813  98.193  -31.665 1.00 31.87  ? 435  ARG   D C     1 
ATOM   6529  O  O     . ARG   F 3 142 ? 25.046  99.255  -32.247 1.00 34.38  ? 435  ARG   D O     1 
ATOM   6530  C  CB    . ARG   F 3 142 ? 23.239  97.941  -29.669 1.00 33.55  ? 435  ARG   D CB    1 
ATOM   6531  C  CG    . ARG   F 3 142 ? 23.562  99.310  -29.091 1.00 35.72  ? 435  ARG   D CG    1 
ATOM   6532  C  CD    . ARG   F 3 142 ? 23.263  99.457  -27.615 1.00 36.77  ? 435  ARG   D CD    1 
ATOM   6533  N  NE    . ARG   F 3 142 ? 24.041  98.550  -26.793 1.00 36.87  ? 435  ARG   D NE    1 
ATOM   6534  C  CZ    . ARG   F 3 142 ? 23.750  98.240  -25.533 1.00 40.65  ? 435  ARG   D CZ    1 
ATOM   6535  N  NH1   . ARG   F 3 142 ? 22.712  98.788  -24.929 1.00 36.61  ? 435  ARG   D NH1   1 
ATOM   6536  N  NH2   . ARG   F 3 142 ? 24.464  97.326  -24.903 1.00 40.73  ? 435  ARG   D NH2   1 
ATOM   6537  N  N     . PRO   F 3 143 ? 25.824  97.319  -31.445 1.00 29.95  ? 436  PRO   D N     1 
ATOM   6538  C  CA    . PRO   F 3 143 ? 27.164  97.602  -31.961 1.00 28.91  ? 436  PRO   D CA    1 
ATOM   6539  C  C     . PRO   F 3 143 ? 27.250  97.718  -33.487 1.00 29.79  ? 436  PRO   D C     1 
ATOM   6540  O  O     . PRO   F 3 143 ? 28.073  98.483  -34.003 1.00 30.81  ? 436  PRO   D O     1 
ATOM   6541  C  CB    . PRO   F 3 143 ? 28.047  96.481  -31.385 1.00 28.96  ? 436  PRO   D CB    1 
ATOM   6542  C  CG    . PRO   F 3 143 ? 27.110  95.439  -30.848 1.00 28.98  ? 436  PRO   D CG    1 
ATOM   6543  C  CD    . PRO   F 3 143 ? 25.782  96.117  -30.605 1.00 27.61  ? 436  PRO   D CD    1 
ATOM   6544  N  N     . LEU   F 3 144 ? 26.375  97.006  -34.207 1.00 30.09  ? 437  LEU   D N     1 
ATOM   6545  C  CA    . LEU   F 3 144 ? 26.355  97.081  -35.665 1.00 30.37  ? 437  LEU   D CA    1 
ATOM   6546  C  C     . LEU   F 3 144 ? 25.939  98.464  -36.131 1.00 31.36  ? 437  LEU   D C     1 
ATOM   6547  O  O     . LEU   F 3 144 ? 26.383  98.906  -37.192 1.00 29.56  ? 437  LEU   D O     1 
ATOM   6548  C  CB    . LEU   F 3 144 ? 25.388  96.052  -36.252 1.00 31.51  ? 437  LEU   D CB    1 
ATOM   6549  C  CG    . LEU   F 3 144 ? 25.296  96.034  -37.785 1.00 30.26  ? 437  LEU   D CG    1 
ATOM   6550  C  CD1   . LEU   F 3 144 ? 26.587  95.539  -38.402 1.00 31.99  ? 437  LEU   D CD1   1 
ATOM   6551  C  CD2   . LEU   F 3 144 ? 24.142  95.172  -38.261 1.00 28.89  ? 437  LEU   D CD2   1 
ATOM   6552  N  N     . SER   F 3 145 ? 25.042  99.111  -35.371 1.00 35.77  ? 438  SER   D N     1 
ATOM   6553  C  CA    . SER   F 3 145 ? 24.548  100.425 -35.756 1.00 31.93  ? 438  SER   D CA    1 
ATOM   6554  C  C     . SER   F 3 145 ? 25.733  101.380 -35.896 1.00 31.28  ? 438  SER   D C     1 
ATOM   6555  O  O     . SER   F 3 145 ? 25.754  102.211 -36.796 1.00 34.54  ? 438  SER   D O     1 
ATOM   6556  C  CB    . SER   F 3 145 ? 23.459  100.926 -34.821 1.00 31.52  ? 438  SER   D CB    1 
ATOM   6557  O  OG    . SER   F 3 145 ? 23.950  101.244 -33.527 1.00 29.64  ? 438  SER   D OG    1 
ATOM   6558  N  N     . ALA   F 3 146 ? 26.739  101.225 -35.023 1.00 31.02  ? 439  ALA   D N     1 
ATOM   6559  C  CA    . ALA   F 3 146 ? 27.942  102.041 -35.074 1.00 30.76  ? 439  ALA   D CA    1 
ATOM   6560  C  C     . ALA   F 3 146 ? 28.776  101.709 -36.305 1.00 31.61  ? 439  ALA   D C     1 
ATOM   6561  O  O     . ALA   F 3 146 ? 29.391  102.599 -36.896 1.00 34.64  ? 439  ALA   D O     1 
ATOM   6562  C  CB    . ALA   F 3 146 ? 28.775  101.845 -33.837 1.00 32.28  ? 439  ALA   D CB    1 
ATOM   6563  N  N     . VAL   F 3 147 ? 28.854  100.418 -36.645 1.00 31.55  ? 440  VAL   D N     1 
ATOM   6564  C  CA    . VAL   F 3 147 ? 29.540  100.007 -37.860 1.00 30.33  ? 440  VAL   D CA    1 
ATOM   6565  C  C     . VAL   F 3 147 ? 28.864  100.668 -39.069 1.00 30.72  ? 440  VAL   D C     1 
ATOM   6566  O  O     . VAL   F 3 147 ? 29.543  101.217 -39.936 1.00 29.92  ? 440  VAL   D O     1 
ATOM   6567  C  CB    . VAL   F 3 147 ? 29.582  98.475  -37.976 1.00 29.59  ? 440  VAL   D CB    1 
ATOM   6568  C  CG1   . VAL   F 3 147 ? 30.198  98.026  -39.285 1.00 30.22  ? 440  VAL   D CG1   1 
ATOM   6569  C  CG2   . VAL   F 3 147 ? 30.318  97.855  -36.793 1.00 32.83  ? 440  VAL   D CG2   1 
ATOM   6570  N  N     . LEU   F 3 148 ? 27.525  100.614 -39.127 1.00 29.32  ? 441  LEU   D N     1 
ATOM   6571  C  CA    . LEU   F 3 148 ? 26.798  101.105 -40.288 1.00 30.79  ? 441  LEU   D CA    1 
ATOM   6572  C  C     . LEU   F 3 148 ? 26.976  102.619 -40.431 1.00 34.95  ? 441  LEU   D C     1 
ATOM   6573  O  O     . LEU   F 3 148 ? 27.077  103.130 -41.548 1.00 35.71  ? 441  LEU   D O     1 
ATOM   6574  C  CB    . LEU   F 3 148 ? 25.317  100.739 -40.138 1.00 31.82  ? 441  LEU   D CB    1 
ATOM   6575  C  CG    . LEU   F 3 148 ? 24.980  99.243  -40.141 1.00 26.60  ? 441  LEU   D CG    1 
ATOM   6576  C  CD1   . LEU   F 3 148 ? 23.485  99.047  -40.100 1.00 24.84  ? 441  LEU   D CD1   1 
ATOM   6577  C  CD2   . LEU   F 3 148 ? 25.558  98.555  -41.368 1.00 28.27  ? 441  LEU   D CD2   1 
ATOM   6578  N  N     . ALA   F 3 149 ? 27.030  103.327 -39.295 1.00 34.78  ? 442  ALA   D N     1 
ATOM   6579  C  CA    . ALA   F 3 149 ? 27.250  104.764 -39.281 1.00 37.30  ? 442  ALA   D CA    1 
ATOM   6580  C  C     . ALA   F 3 149 ? 28.569  105.099 -39.979 1.00 36.68  ? 442  ALA   D C     1 
ATOM   6581  O  O     . ALA   F 3 149 ? 28.635  105.992 -40.817 1.00 33.48  ? 442  ALA   D O     1 
ATOM   6582  C  CB    . ALA   F 3 149 ? 27.236  105.270 -37.861 1.00 39.44  ? 442  ALA   D CB    1 
ATOM   6583  N  N     . HIS   F 3 150 ? 29.634  104.372 -39.654 1.00 36.91  ? 443  HIS   D N     1 
ATOM   6584  C  CA    . HIS   F 3 150 ? 30.906  104.616 -40.312 1.00 35.05  ? 443  HIS   D CA    1 
ATOM   6585  C  C     . HIS   F 3 150 ? 30.811  104.316 -41.807 1.00 37.09  ? 443  HIS   D C     1 
ATOM   6586  O  O     . HIS   F 3 150 ? 31.379  105.030 -42.629 1.00 41.56  ? 443  HIS   D O     1 
ATOM   6587  C  CB    . HIS   F 3 150 ? 32.015  103.837 -39.604 1.00 39.30  ? 443  HIS   D CB    1 
ATOM   6588  C  CG    . HIS   F 3 150 ? 32.474  104.471 -38.321 1.00 42.79  ? 443  HIS   D CG    1 
ATOM   6589  N  ND1   . HIS   F 3 150 ? 32.132  104.013 -37.067 1.00 46.13  ? 443  HIS   D ND1   1 
ATOM   6590  C  CD2   . HIS   F 3 150 ? 33.226  105.595 -38.130 1.00 45.63  ? 443  HIS   D CD2   1 
ATOM   6591  C  CE1   . HIS   F 3 150 ? 32.695  104.791 -36.141 1.00 46.32  ? 443  HIS   D CE1   1 
ATOM   6592  N  NE2   . HIS   F 3 150 ? 33.364  105.789 -36.778 1.00 43.97  ? 443  HIS   D NE2   1 
ATOM   6593  N  N     . MET   F 3 151 ? 30.081  103.259 -42.168 1.00 36.77  ? 444  MET   D N     1 
ATOM   6594  C  CA    . MET   F 3 151 ? 30.054  102.801 -43.539 1.00 33.17  ? 444  MET   D CA    1 
ATOM   6595  C  C     . MET   F 3 151 ? 29.376  103.869 -44.389 1.00 34.39  ? 444  MET   D C     1 
ATOM   6596  O  O     . MET   F 3 151 ? 29.880  104.264 -45.442 1.00 34.06  ? 444  MET   D O     1 
ATOM   6597  C  CB    . MET   F 3 151 ? 29.294  101.475 -43.643 1.00 32.59  ? 444  MET   D CB    1 
ATOM   6598  C  CG    . MET   F 3 151 ? 30.112  100.287 -43.152 1.00 34.38  ? 444  MET   D CG    1 
ATOM   6599  S  SD    . MET   F 3 151 ? 29.189  98.748  -43.094 1.00 30.94  ? 444  MET   D SD    1 
ATOM   6600  C  CE    . MET   F 3 151 ? 28.996  98.365  -44.829 1.00 30.06  ? 444  MET   D CE    1 
ATOM   6601  N  N     . GLU   F 3 152 ? 28.231  104.338 -43.895 1.00 33.46  ? 445  GLU   D N     1 
ATOM   6602  C  CA    . GLU   F 3 152 ? 27.460  105.378 -44.552 1.00 34.08  ? 445  GLU   D CA    1 
ATOM   6603  C  C     . GLU   F 3 152 ? 28.277  106.650 -44.748 1.00 34.66  ? 445  GLU   D C     1 
ATOM   6604  O  O     . GLU   F 3 152 ? 28.201  107.247 -45.816 1.00 38.19  ? 445  GLU   D O     1 
ATOM   6605  C  CB    . GLU   F 3 152 ? 26.220  105.724 -43.731 1.00 35.26  ? 445  GLU   D CB    1 
ATOM   6606  C  CG    . GLU   F 3 152 ? 25.202  104.608 -43.723 1.00 36.78  ? 445  GLU   D CG    1 
ATOM   6607  C  CD    . GLU   F 3 152 ? 23.793  104.965 -43.304 1.00 37.55  ? 445  GLU   D CD    1 
ATOM   6608  O  OE1   . GLU   F 3 152 ? 23.434  106.178 -43.280 1.00 38.61  ? 445  GLU   D OE1   1 
ATOM   6609  O  OE2   . GLU   F 3 152 ? 23.047  104.013 -43.058 1.00 36.69  ? 445  GLU   D OE2   1 
ATOM   6610  N  N     . ALA   F 3 153 ? 28.981  107.099 -43.703 1.00 35.82  ? 446  ALA   D N     1 
ATOM   6611  C  CA    . ALA   F 3 153 ? 29.687  108.383 -43.732 1.00 38.19  ? 446  ALA   D CA    1 
ATOM   6612  C  C     . ALA   F 3 153 ? 30.990  108.300 -44.544 1.00 40.42  ? 446  ALA   D C     1 
ATOM   6613  O  O     . ALA   F 3 153 ? 31.510  109.323 -44.989 1.00 37.16  ? 446  ALA   D O     1 
ATOM   6614  C  CB    . ALA   F 3 153 ? 29.942  108.856 -42.320 1.00 34.53  ? 446  ALA   D CB    1 
ATOM   6615  N  N     . THR   F 3 154 ? 31.514  107.085 -44.752 1.00 37.82  ? 447  THR   D N     1 
ATOM   6616  C  CA    . THR   F 3 154 ? 32.745  106.895 -45.505 1.00 35.72  ? 447  THR   D CA    1 
ATOM   6617  C  C     . THR   F 3 154 ? 32.461  106.947 -47.004 1.00 35.99  ? 447  THR   D C     1 
ATOM   6618  O  O     . THR   F 3 154 ? 33.208  107.562 -47.758 1.00 41.38  ? 447  THR   D O     1 
ATOM   6619  C  CB    . THR   F 3 154 ? 33.413  105.554 -45.162 1.00 37.12  ? 447  THR   D CB    1 
ATOM   6620  O  OG1   . THR   F 3 154 ? 33.693  105.489 -43.761 1.00 35.14  ? 447  THR   D OG1   1 
ATOM   6621  C  CG2   . THR   F 3 154 ? 34.695  105.332 -45.935 1.00 36.71  ? 447  THR   D CG2   1 
ATOM   6622  N  N     . GLY   F 3 155 ? 31.409  106.259 -47.452 1.00 35.38  ? 448  GLY   D N     1 
ATOM   6623  C  CA    . GLY   F 3 155 ? 31.096  106.195 -48.870 1.00 35.75  ? 448  GLY   D CA    1 
ATOM   6624  C  C     . GLY   F 3 155 ? 32.141  105.438 -49.700 1.00 35.88  ? 448  GLY   D C     1 
ATOM   6625  O  O     . GLY   F 3 155 ? 33.077  104.827 -49.173 1.00 35.58  ? 448  GLY   D O     1 
ATOM   6626  N  N     . VAL   F 3 156 ? 31.958  105.503 -51.023 1.00 39.17  ? 449  VAL   D N     1 
ATOM   6627  C  CA    . VAL   F 3 156 ? 32.773  104.786 -51.994 1.00 40.81  ? 449  VAL   D CA    1 
ATOM   6628  C  C     . VAL   F 3 156 ? 33.100  105.735 -53.151 1.00 41.50  ? 449  VAL   D C     1 
ATOM   6629  O  O     . VAL   F 3 156 ? 32.247  106.484 -53.617 1.00 39.88  ? 449  VAL   D O     1 
ATOM   6630  C  CB    . VAL   F 3 156 ? 32.077  103.510 -52.516 1.00 41.27  ? 449  VAL   D CB    1 
ATOM   6631  C  CG1   . VAL   F 3 156 ? 30.744  103.800 -53.182 1.00 43.14  ? 449  VAL   D CG1   1 
ATOM   6632  C  CG2   . VAL   F 3 156 ? 32.961  102.741 -53.497 1.00 48.68  ? 449  VAL   D CG2   1 
ATOM   6633  N  N     . ARG   F 3 157 ? 34.343  105.661 -53.634 1.00 39.44  ? 450  ARG   D N     1 
ATOM   6634  C  CA    . ARG   F 3 157 ? 34.773  106.454 -54.765 1.00 39.26  ? 450  ARG   D CA    1 
ATOM   6635  C  C     . ARG   F 3 157 ? 34.216  105.884 -56.066 1.00 41.99  ? 450  ARG   D C     1 
ATOM   6636  O  O     . ARG   F 3 157 ? 34.091  104.671 -56.240 1.00 39.90  ? 450  ARG   D O     1 
ATOM   6637  C  CB    . ARG   F 3 157 ? 36.302  106.480 -54.797 1.00 42.93  ? 450  ARG   D CB    1 
ATOM   6638  C  CG    . ARG   F 3 157 ? 36.871  107.491 -55.778 1.00 47.74  ? 450  ARG   D CG    1 
ATOM   6639  C  CD    . ARG   F 3 157 ? 38.388  107.484 -55.782 1.00 53.66  ? 450  ARG   D CD    1 
ATOM   6640  N  NE    . ARG   F 3 157 ? 38.964  108.340 -56.820 1.00 55.61  ? 450  ARG   D NE    1 
ATOM   6641  C  CZ    . ARG   F 3 157 ? 40.204  108.221 -57.295 1.00 55.93  ? 450  ARG   D CZ    1 
ATOM   6642  N  NH1   . ARG   F 3 157 ? 40.948  107.170 -56.989 1.00 52.54  ? 450  ARG   D NH1   1 
ATOM   6643  N  NH2   . ARG   F 3 157 ? 40.689  109.157 -58.089 1.00 58.87  ? 450  ARG   D NH2   1 
ATOM   6644  N  N     . LEU   F 3 158 ? 33.995  106.787 -57.025 1.00 41.10  ? 451  LEU   D N     1 
ATOM   6645  C  CA    . LEU   F 3 158 ? 33.392  106.465 -58.303 1.00 40.06  ? 451  LEU   D CA    1 
ATOM   6646  C  C     . LEU   F 3 158 ? 34.272  107.021 -59.431 1.00 43.25  ? 451  LEU   D C     1 
ATOM   6647  O  O     . LEU   F 3 158 ? 34.820  108.118 -59.313 1.00 47.86  ? 451  LEU   D O     1 
ATOM   6648  C  CB    . LEU   F 3 158 ? 32.020  107.131 -58.230 1.00 41.30  ? 451  LEU   D CB    1 
ATOM   6649  C  CG    . LEU   F 3 158 ? 30.857  106.387 -58.860 1.00 42.83  ? 451  LEU   D CG    1 
ATOM   6650  C  CD1   . LEU   F 3 158 ? 30.621  105.069 -58.163 1.00 44.45  ? 451  LEU   D CD1   1 
ATOM   6651  C  CD2   . LEU   F 3 158 ? 29.614  107.247 -58.795 1.00 42.74  ? 451  LEU   D CD2   1 
ATOM   6652  N  N     . ASP   F 3 159 ? 34.462  106.248 -60.510 1.00 47.86  ? 452  ASP   D N     1 
ATOM   6653  C  CA    . ASP   F 3 159 ? 35.162  106.730 -61.697 1.00 47.27  ? 452  ASP   D CA    1 
ATOM   6654  C  C     . ASP   F 3 159 ? 34.171  107.479 -62.587 1.00 45.45  ? 452  ASP   D C     1 
ATOM   6655  O  O     . ASP   F 3 159 ? 33.501  106.869 -63.427 1.00 44.76  ? 452  ASP   D O     1 
ATOM   6656  C  CB    . ASP   F 3 159 ? 35.832  105.589 -62.467 1.00 49.87  ? 452  ASP   D CB    1 
ATOM   6657  C  CG    . ASP   F 3 159 ? 36.796  106.038 -63.562 1.00 51.05  ? 452  ASP   D CG    1 
ATOM   6658  O  OD1   . ASP   F 3 159 ? 36.768  107.220 -63.954 1.00 53.30  ? 452  ASP   D OD1   1 
ATOM   6659  O  OD2   . ASP   F 3 159 ? 37.595  105.208 -63.993 1.00 52.40  ? 452  ASP   D OD2   1 
ATOM   6660  N  N     . VAL   F 3 160 ? 34.103  108.803 -62.384 1.00 44.27  ? 453  VAL   D N     1 
ATOM   6661  C  CA    . VAL   F 3 160 ? 33.077  109.667 -62.967 1.00 47.75  ? 453  VAL   D CA    1 
ATOM   6662  C  C     . VAL   F 3 160 ? 33.218  109.745 -64.492 1.00 43.68  ? 453  VAL   D C     1 
ATOM   6663  O  O     . VAL   F 3 160 ? 32.217  109.648 -65.200 1.00 44.92  ? 453  VAL   D O     1 
ATOM   6664  C  CB    . VAL   F 3 160 ? 33.130  111.073 -62.332 1.00 54.66  ? 453  VAL   D CB    1 
ATOM   6665  C  CG1   . VAL   F 3 160 ? 32.217  112.060 -63.049 1.00 59.07  ? 453  VAL   D CG1   1 
ATOM   6666  C  CG2   . VAL   F 3 160 ? 32.818  111.037 -60.839 1.00 51.45  ? 453  VAL   D CG2   1 
ATOM   6667  N  N     . ALA   F 3 161 ? 34.454  109.907 -64.990 1.00 40.61  ? 454  ALA   D N     1 
ATOM   6668  C  CA    . ALA   F 3 161 ? 34.722  110.108 -66.407 1.00 46.48  ? 454  ALA   D CA    1 
ATOM   6669  C  C     . ALA   F 3 161 ? 34.356  108.862 -67.222 1.00 47.23  ? 454  ALA   D C     1 
ATOM   6670  O  O     . ALA   F 3 161 ? 33.786  108.941 -68.315 1.00 44.92  ? 454  ALA   D O     1 
ATOM   6671  C  CB    . ALA   F 3 161 ? 36.186  110.472 -66.578 1.00 44.73  ? 454  ALA   D CB    1 
ATOM   6672  N  N     . TYR   F 3 162 ? 34.713  107.703 -66.661 1.00 47.02  ? 455  TYR   D N     1 
ATOM   6673  C  CA    . TYR   F 3 162 ? 34.348  106.400 -67.191 1.00 41.58  ? 455  TYR   D CA    1 
ATOM   6674  C  C     . TYR   F 3 162 ? 32.831  106.284 -67.358 1.00 39.53  ? 455  TYR   D C     1 
ATOM   6675  O  O     . TYR   F 3 162 ? 32.358  105.846 -68.401 1.00 40.33  ? 455  TYR   D O     1 
ATOM   6676  C  CB    . TYR   F 3 162 ? 34.909  105.332 -66.250 1.00 42.94  ? 455  TYR   D CB    1 
ATOM   6677  C  CG    . TYR   F 3 162 ? 34.643  103.922 -66.700 1.00 46.36  ? 455  TYR   D CG    1 
ATOM   6678  C  CD1   . TYR   F 3 162 ? 35.490  103.271 -67.587 1.00 45.84  ? 455  TYR   D CD1   1 
ATOM   6679  C  CD2   . TYR   F 3 162 ? 33.498  103.264 -66.286 1.00 46.32  ? 455  TYR   D CD2   1 
ATOM   6680  C  CE1   . TYR   F 3 162 ? 35.236  101.980 -68.017 1.00 45.63  ? 455  TYR   D CE1   1 
ATOM   6681  C  CE2   . TYR   F 3 162 ? 33.220  101.981 -66.722 1.00 49.40  ? 455  TYR   D CE2   1 
ATOM   6682  C  CZ    . TYR   F 3 162 ? 34.091  101.333 -67.579 1.00 50.50  ? 455  TYR   D CZ    1 
ATOM   6683  O  OH    . TYR   F 3 162 ? 33.769  100.053 -67.974 1.00 54.92  ? 455  TYR   D OH    1 
ATOM   6684  N  N     . LEU   F 3 163 ? 32.062  106.687 -66.335 1.00 38.20  ? 456  LEU   D N     1 
ATOM   6685  C  CA    . LEU   F 3 163 ? 30.605  106.602 -66.385 1.00 39.62  ? 456  LEU   D CA    1 
ATOM   6686  C  C     . LEU   F 3 163 ? 30.005  107.562 -67.415 1.00 39.40  ? 456  LEU   D C     1 
ATOM   6687  O  O     . LEU   F 3 163 ? 29.042  107.207 -68.088 1.00 37.92  ? 456  LEU   D O     1 
ATOM   6688  C  CB    . LEU   F 3 163 ? 30.036  106.886 -64.989 1.00 40.23  ? 456  LEU   D CB    1 
ATOM   6689  C  CG    . LEU   F 3 163 ? 30.087  105.706 -64.013 1.00 42.52  ? 456  LEU   D CG    1 
ATOM   6690  C  CD1   . LEU   F 3 163 ? 29.730  106.133 -62.599 1.00 48.47  ? 456  LEU   D CD1   1 
ATOM   6691  C  CD2   . LEU   F 3 163 ? 29.159  104.594 -64.452 1.00 44.85  ? 456  LEU   D CD2   1 
ATOM   6692  N  N     . ARG   F 3 164 ? 30.529  108.792 -67.488 1.00 41.38  ? 457  ARG   D N     1 
ATOM   6693  C  CA    . ARG   F 3 164 ? 30.118  109.771 -68.494 1.00 44.96  ? 457  ARG   D CA    1 
ATOM   6694  C  C     . ARG   F 3 164 ? 30.316  109.198 -69.911 1.00 40.48  ? 457  ARG   D C     1 
ATOM   6695  O  O     . ARG   F 3 164 ? 29.421  109.238 -70.754 1.00 39.27  ? 457  ARG   D O     1 
ATOM   6696  C  CB    . ARG   F 3 164 ? 30.894  111.080 -68.286 1.00 43.44  ? 457  ARG   D CB    1 
ATOM   6697  C  CG    . ARG   F 3 164 ? 30.162  112.174 -67.522 1.00 44.25  ? 457  ARG   D CG    1 
ATOM   6698  C  CD    . ARG   F 3 164 ? 29.634  111.842 -66.149 1.00 44.31  ? 457  ARG   D CD    1 
ATOM   6699  N  NE    . ARG   F 3 164 ? 29.359  113.018 -65.329 1.00 38.47  ? 457  ARG   D NE    1 
ATOM   6700  C  CZ    . ARG   F 3 164 ? 28.279  113.219 -64.573 1.00 35.98  ? 457  ARG   D CZ    1 
ATOM   6701  N  NH1   . ARG   F 3 164 ? 28.382  113.933 -63.470 1.00 33.67  ? 457  ARG   D NH1   1 
ATOM   6702  N  NH2   . ARG   F 3 164 ? 27.095  112.744 -64.909 1.00 37.19  ? 457  ARG   D NH2   1 
ATOM   6703  N  N     . ALA   F 3 165 ? 31.480  108.610 -70.176 1.00 38.10  ? 458  ALA   D N     1 
ATOM   6704  C  CA    . ALA   F 3 165 ? 31.747  107.999 -71.474 1.00 39.77  ? 458  ALA   D CA    1 
ATOM   6705  C  C     . ALA   F 3 165 ? 30.773  106.847 -71.741 1.00 42.73  ? 458  ALA   D C     1 
ATOM   6706  O  O     . ALA   F 3 165 ? 30.316  106.674 -72.870 1.00 42.98  ? 458  ALA   D O     1 
ATOM   6707  C  CB    . ALA   F 3 165 ? 33.196  107.544 -71.534 1.00 37.20  ? 458  ALA   D CB    1 
ATOM   6708  N  N     . LEU   F 3 166 ? 30.438  106.065 -70.701 1.00 41.21  ? 459  LEU   D N     1 
ATOM   6709  C  CA    . LEU   F 3 166 ? 29.536  104.931 -70.853 1.00 40.62  ? 459  LEU   D CA    1 
ATOM   6710  C  C     . LEU   F 3 166 ? 28.105  105.396 -71.152 1.00 38.44  ? 459  LEU   D C     1 
ATOM   6711  O  O     . LEU   F 3 166 ? 27.388  104.736 -71.911 1.00 38.37  ? 459  LEU   D O     1 
ATOM   6712  C  CB    . LEU   F 3 166 ? 29.623  104.077 -69.579 1.00 45.90  ? 459  LEU   D CB    1 
ATOM   6713  C  CG    . LEU   F 3 166 ? 28.897  102.729 -69.602 1.00 45.25  ? 459  LEU   D CG    1 
ATOM   6714  C  CD1   . LEU   F 3 166 ? 29.392  101.846 -70.736 1.00 48.29  ? 459  LEU   D CD1   1 
ATOM   6715  C  CD2   . LEU   F 3 166 ? 29.076  102.004 -68.278 1.00 48.52  ? 459  LEU   D CD2   1 
ATOM   6716  N  N     . SER   F 3 167 ? 27.675  106.520 -70.556 1.00 36.89  ? 460  SER   D N     1 
ATOM   6717  C  CA    . SER   F 3 167 ? 26.358  107.095 -70.839 1.00 38.72  ? 460  SER   D CA    1 
ATOM   6718  C  C     . SER   F 3 167 ? 26.200  107.410 -72.334 1.00 42.17  ? 460  SER   D C     1 
ATOM   6719  O  O     . SER   F 3 167 ? 25.183  107.083 -72.949 1.00 43.13  ? 460  SER   D O     1 
ATOM   6720  C  CB    . SER   F 3 167 ? 26.106  108.335 -70.007 1.00 35.69  ? 460  SER   D CB    1 
ATOM   6721  O  OG    . SER   F 3 167 ? 24.760  108.763 -70.182 1.00 33.92  ? 460  SER   D OG    1 
ATOM   6722  N  N     . LEU   F 3 168 ? 27.233  108.040 -72.910 1.00 43.34  ? 461  LEU   D N     1 
ATOM   6723  C  CA    . LEU   F 3 168 ? 27.278  108.425 -74.314 1.00 42.81  ? 461  LEU   D CA    1 
ATOM   6724  C  C     . LEU   F 3 168 ? 27.234  107.161 -75.178 1.00 42.27  ? 461  LEU   D C     1 
ATOM   6725  O  O     . LEU   F 3 168 ? 26.461  107.036 -76.124 1.00 44.66  ? 461  LEU   D O     1 
ATOM   6726  C  CB    . LEU   F 3 168 ? 28.565  109.248 -74.479 1.00 49.76  ? 461  LEU   D CB    1 
ATOM   6727  C  CG    . LEU   F 3 168 ? 28.818  109.968 -75.805 1.00 55.96  ? 461  LEU   D CG    1 
ATOM   6728  C  CD1   . LEU   F 3 168 ? 29.729  111.164 -75.580 1.00 55.71  ? 461  LEU   D CD1   1 
ATOM   6729  C  CD2   . LEU   F 3 168 ? 29.450  109.037 -76.836 1.00 59.98  ? 461  LEU   D CD2   1 
ATOM   6730  N  N     . GLU   F 3 169 ? 28.025  106.168 -74.803 1.00 42.77  ? 462  GLU   D N     1 
ATOM   6731  C  CA    . GLU   F 3 169 ? 28.081  104.937 -75.569 1.00 42.41  ? 462  GLU   D CA    1 
ATOM   6732  C  C     . GLU   F 3 169 ? 26.737  104.204 -75.545 1.00 42.23  ? 462  GLU   D C     1 
ATOM   6733  O  O     . GLU   F 3 169 ? 26.311  103.652 -76.558 1.00 43.29  ? 462  GLU   D O     1 
ATOM   6734  C  CB    . GLU   F 3 169 ? 29.217  104.080 -75.016 1.00 43.62  ? 462  GLU   D CB    1 
ATOM   6735  C  CG    . GLU   F 3 169 ? 29.209  102.681 -75.586 1.00 50.18  ? 462  GLU   D CG    1 
ATOM   6736  C  CD    . GLU   F 3 169 ? 30.368  101.837 -75.109 1.00 51.46  ? 462  GLU   D CD    1 
ATOM   6737  O  OE1   . GLU   F 3 169 ? 31.263  102.412 -74.444 1.00 52.76  ? 462  GLU   D OE1   1 
ATOM   6738  O  OE2   . GLU   F 3 169 ? 30.348  100.619 -75.397 1.00 55.10  ? 462  GLU   D OE2   1 
ATOM   6739  N  N     . VAL   F 3 170 ? 26.076  104.190 -74.380 1.00 39.33  ? 463  VAL   D N     1 
ATOM   6740  C  CA    . VAL   F 3 170 ? 24.813  103.483 -74.204 1.00 37.97  ? 463  VAL   D CA    1 
ATOM   6741  C  C     . VAL   F 3 170 ? 23.678  104.228 -74.907 1.00 34.91  ? 463  VAL   D C     1 
ATOM   6742  O  O     . VAL   F 3 170 ? 22.846  103.578 -75.527 1.00 40.99  ? 463  VAL   D O     1 
ATOM   6743  C  CB    . VAL   F 3 170 ? 24.510  103.262 -72.700 1.00 41.22  ? 463  VAL   D CB    1 
ATOM   6744  C  CG1   . VAL   F 3 170 ? 23.074  102.816 -72.448 1.00 44.46  ? 463  VAL   D CG1   1 
ATOM   6745  C  CG2   . VAL   F 3 170 ? 25.481  102.269 -72.081 1.00 41.75  ? 463  VAL   D CG2   1 
ATOM   6746  N  N     . ALA   F 3 171 ? 23.613  105.568 -74.761 1.00 36.85  ? 464  ALA   D N     1 
ATOM   6747  C  CA    . ALA   F 3 171 ? 22.654  106.417 -75.475 1.00 36.85  ? 464  ALA   D CA    1 
ATOM   6748  C  C     . ALA   F 3 171 ? 22.627  106.075 -76.968 1.00 36.24  ? 464  ALA   D C     1 
ATOM   6749  O  O     . ALA   F 3 171 ? 21.548  105.872 -77.533 1.00 40.14  ? 464  ALA   D O     1 
ATOM   6750  C  CB    . ALA   F 3 171 ? 22.972  107.885 -75.256 1.00 34.68  ? 464  ALA   D CB    1 
ATOM   6751  N  N     . GLU   F 3 172 ? 23.818  105.964 -77.581 1.00 37.69  ? 465  GLU   D N     1 
ATOM   6752  C  CA    . GLU   F 3 172 ? 23.946  105.650 -79.003 1.00 40.48  ? 465  GLU   D CA    1 
ATOM   6753  C  C     . GLU   F 3 172 ? 23.348  104.277 -79.311 1.00 42.11  ? 465  GLU   D C     1 
ATOM   6754  O  O     . GLU   F 3 172 ? 22.704  104.099 -80.351 1.00 43.14  ? 465  GLU   D O     1 
ATOM   6755  C  CB    . GLU   F 3 172 ? 25.408  105.722 -79.476 1.00 40.63  ? 465  GLU   D CB    1 
ATOM   6756  C  CG    . GLU   F 3 172 ? 25.565  105.568 -80.997 1.00 42.49  ? 465  GLU   D CG    1 
ATOM   6757  C  CD    . GLU   F 3 172 ? 25.613  104.158 -81.583 1.00 48.51  ? 465  GLU   D CD    1 
ATOM   6758  O  OE1   . GLU   F 3 172 ? 25.966  103.207 -80.847 1.00 50.29  ? 465  GLU   D OE1   1 
ATOM   6759  O  OE2   . GLU   F 3 172 ? 25.307  103.998 -82.784 1.00 51.91  ? 465  GLU   D OE2   1 
ATOM   6760  N  N     . GLU   F 3 173 ? 23.577  103.299 -78.425 1.00 43.62  ? 466  GLU   D N     1 
ATOM   6761  C  CA    . GLU   F 3 173 ? 23.046  101.961 -78.650 1.00 47.10  ? 466  GLU   D CA    1 
ATOM   6762  C  C     . GLU   F 3 173 ? 21.524  102.007 -78.529 1.00 43.89  ? 466  GLU   D C     1 
ATOM   6763  O  O     . GLU   F 3 173 ? 20.805  101.371 -79.306 1.00 43.36  ? 466  GLU   D O     1 
ATOM   6764  C  CB    . GLU   F 3 173 ? 23.661  100.951 -77.677 1.00 54.39  ? 466  GLU   D CB    1 
ATOM   6765  C  CG    . GLU   F 3 173 ? 24.604  99.949  -78.312 1.00 63.15  ? 466  GLU   D CG    1 
ATOM   6766  C  CD    . GLU   F 3 173 ? 23.947  98.662  -78.801 1.00 73.71  ? 466  GLU   D CD    1 
ATOM   6767  O  OE1   . GLU   F 3 173 ? 24.016  97.655  -78.060 1.00 73.95  ? 466  GLU   D OE1   1 
ATOM   6768  O  OE2   . GLU   F 3 173 ? 23.386  98.650  -79.929 1.00 76.07  ? 466  GLU   D OE2   1 
ATOM   6769  N  N     . ILE   F 3 174 ? 21.028  102.761 -77.544 1.00 43.79  ? 467  ILE   D N     1 
ATOM   6770  C  CA    . ILE   F 3 174 ? 19.592  102.844 -77.318 1.00 45.61  ? 467  ILE   D CA    1 
ATOM   6771  C  C     . ILE   F 3 174 ? 18.906  103.415 -78.567 1.00 47.85  ? 467  ILE   D C     1 
ATOM   6772  O  O     . ILE   F 3 174 ? 17.894  102.870 -79.017 1.00 44.64  ? 467  ILE   D O     1 
ATOM   6773  C  CB    . ILE   F 3 174 ? 19.275  103.651 -76.040 1.00 44.82  ? 467  ILE   D CB    1 
ATOM   6774  C  CG1   . ILE   F 3 174 ? 19.709  102.885 -74.778 1.00 44.49  ? 467  ILE   D CG1   1 
ATOM   6775  C  CG2   . ILE   F 3 174 ? 17.794  104.020 -76.005 1.00 43.15  ? 467  ILE   D CG2   1 
ATOM   6776  C  CD1   . ILE   F 3 174 ? 19.732  103.708 -73.504 1.00 42.27  ? 467  ILE   D CD1   1 
ATOM   6777  N  N     . ALA   F 3 175 ? 19.460  104.505 -79.127 1.00 47.18  ? 468  ALA   D N     1 
ATOM   6778  C  CA    . ALA   F 3 175 ? 18.890  105.115 -80.328 1.00 50.75  ? 468  ALA   D CA    1 
ATOM   6779  C  C     . ALA   F 3 175 ? 18.852  104.099 -81.473 1.00 47.78  ? 468  ALA   D C     1 
ATOM   6780  O  O     . ALA   F 3 175 ? 17.836  103.943 -82.151 1.00 52.92  ? 468  ALA   D O     1 
ATOM   6781  C  CB    . ALA   F 3 175 ? 19.659  106.360 -80.696 1.00 46.97  ? 468  ALA   D CB    1 
ATOM   6782  N  N     . ARG   F 3 176 ? 19.942  103.349 -81.636 1.00 51.37  ? 469  ARG   D N     1 
ATOM   6783  C  CA    . ARG   F 3 176 ? 20.048  102.410 -82.739 1.00 53.83  ? 469  ARG   D CA    1 
ATOM   6784  C  C     . ARG   F 3 176 ? 19.000  101.313 -82.592 1.00 53.58  ? 469  ARG   D C     1 
ATOM   6785  O  O     . ARG   F 3 176 ? 18.371  100.950 -83.578 1.00 57.94  ? 469  ARG   D O     1 
ATOM   6786  C  CB    . ARG   F 3 176 ? 21.474  101.854 -82.840 1.00 55.43  ? 469  ARG   D CB    1 
ATOM   6787  C  CG    . ARG   F 3 176 ? 21.660  100.818 -83.941 1.00 58.16  ? 469  ARG   D CG    1 
ATOM   6788  C  CD    . ARG   F 3 176 ? 23.027  100.868 -84.611 1.00 62.53  ? 469  ARG   D CD    1 
ATOM   6789  N  NE    . ARG   F 3 176 ? 24.122  101.034 -83.673 1.00 65.51  ? 469  ARG   D NE    1 
ATOM   6790  C  CZ    . ARG   F 3 176 ? 24.382  100.198 -82.669 1.00 73.76  ? 469  ARG   D CZ    1 
ATOM   6791  N  NH1   . ARG   F 3 176 ? 23.671  99.093  -82.519 1.00 74.61  ? 469  ARG   D NH1   1 
ATOM   6792  N  NH2   . ARG   F 3 176 ? 25.353  100.469 -81.815 1.00 71.88  ? 469  ARG   D NH2   1 
ATOM   6793  N  N     . LEU   F 3 177 ? 18.816  100.798 -81.363 1.00 60.55  ? 470  LEU   D N     1 
ATOM   6794  C  CA    . LEU   F 3 177 ? 17.876  99.713  -81.095 1.00 52.45  ? 470  LEU   D CA    1 
ATOM   6795  C  C     . LEU   F 3 177 ? 16.439  100.209 -81.256 1.00 51.55  ? 470  LEU   D C     1 
ATOM   6796  O  O     . LEU   F 3 177 ? 15.575  99.476  -81.738 1.00 56.63  ? 470  LEU   D O     1 
ATOM   6797  C  CB    . LEU   F 3 177 ? 18.091  99.167  -79.675 1.00 52.75  ? 470  LEU   D CB    1 
ATOM   6798  C  CG    . LEU   F 3 177 ? 19.399  98.412  -79.417 1.00 54.37  ? 470  LEU   D CG    1 
ATOM   6799  C  CD1   . LEU   F 3 177 ? 19.641  98.266  -77.926 1.00 51.61  ? 470  LEU   D CD1   1 
ATOM   6800  C  CD2   . LEU   F 3 177 ? 19.396  97.036  -80.068 1.00 51.78  ? 470  LEU   D CD2   1 
ATOM   6801  N  N     . GLU   F 3 178 ? 16.166  101.444 -80.823 1.00 45.88  ? 471  GLU   D N     1 
ATOM   6802  C  CA    . GLU   F 3 178 ? 14.828  101.995 -80.992 1.00 52.23  ? 471  GLU   D CA    1 
ATOM   6803  C  C     . GLU   F 3 178 ? 14.440  102.002 -82.475 1.00 52.94  ? 471  GLU   D C     1 
ATOM   6804  O  O     . GLU   F 3 178 ? 13.347  101.557 -82.817 1.00 49.39  ? 471  GLU   D O     1 
ATOM   6805  C  CB    . GLU   F 3 178 ? 14.726  103.413 -80.426 1.00 49.75  ? 471  GLU   D CB    1 
ATOM   6806  C  CG    . GLU   F 3 178 ? 13.311  103.938 -80.454 1.00 49.48  ? 471  GLU   D CG    1 
ATOM   6807  C  CD    . GLU   F 3 178 ? 13.176  105.361 -79.955 1.00 53.63  ? 471  GLU   D CD    1 
ATOM   6808  O  OE1   . GLU   F 3 178 ? 13.684  106.274 -80.641 1.00 47.66  ? 471  GLU   D OE1   1 
ATOM   6809  O  OE2   . GLU   F 3 178 ? 12.568  105.549 -78.883 1.00 61.29  ? 471  GLU   D OE2   1 
ATOM   6810  N  N     . ALA   F 3 179 ? 15.342  102.516 -83.330 1.00 55.44  ? 472  ALA   D N     1 
ATOM   6811  C  CA    . ALA   F 3 179 ? 15.123  102.605 -84.770 1.00 58.38  ? 472  ALA   D CA    1 
ATOM   6812  C  C     . ALA   F 3 179 ? 14.880  101.217 -85.351 1.00 62.46  ? 472  ALA   D C     1 
ATOM   6813  O  O     . ALA   F 3 179 ? 13.924  101.011 -86.100 1.00 66.13  ? 472  ALA   D O     1 
ATOM   6814  C  CB    . ALA   F 3 179 ? 16.301  103.270 -85.443 1.00 52.78  ? 472  ALA   D CB    1 
ATOM   6815  N  N     . GLU   F 3 180 ? 15.739  100.264 -84.970 1.00 69.56  ? 473  GLU   D N     1 
ATOM   6816  C  CA    . GLU   F 3 180 ? 15.666  98.901  -85.477 1.00 70.99  ? 473  GLU   D CA    1 
ATOM   6817  C  C     . GLU   F 3 180 ? 14.364  98.228  -85.027 1.00 70.70  ? 473  GLU   D C     1 
ATOM   6818  O  O     . GLU   F 3 180 ? 13.882  97.334  -85.716 1.00 83.03  ? 473  GLU   D O     1 
ATOM   6819  C  CB    . GLU   F 3 180 ? 16.941  98.140  -85.093 1.00 77.45  ? 473  GLU   D CB    1 
ATOM   6820  C  CG    . GLU   F 3 180 ? 18.198  98.659  -85.809 1.00 84.13  ? 473  GLU   D CG    1 
ATOM   6821  C  CD    . GLU   F 3 180 ? 19.559  98.122  -85.358 1.00 92.44  ? 473  GLU   D CD    1 
ATOM   6822  O  OE1   . GLU   F 3 180 ? 19.620  97.403  -84.327 1.00 91.23  ? 473  GLU   D OE1   1 
ATOM   6823  O  OE2   . GLU   F 3 180 ? 20.579  98.421  -86.045 1.00 85.13  ? 473  GLU   D OE2   1 
ATOM   6824  N  N     . VAL   F 3 181 ? 13.766  98.662  -83.904 1.00 71.09  ? 474  VAL   D N     1 
ATOM   6825  C  CA    . VAL   F 3 181 ? 12.507  98.087  -83.433 1.00 68.26  ? 474  VAL   D CA    1 
ATOM   6826  C  C     . VAL   F 3 181 ? 11.310  98.797  -84.079 1.00 67.36  ? 474  VAL   D C     1 
ATOM   6827  O  O     . VAL   F 3 181 ? 10.271  98.168  -84.279 1.00 61.43  ? 474  VAL   D O     1 
ATOM   6828  C  CB    . VAL   F 3 181 ? 12.395  98.098  -81.890 1.00 67.48  ? 474  VAL   D CB    1 
ATOM   6829  C  CG1   . VAL   F 3 181 ? 11.015  97.660  -81.408 1.00 65.11  ? 474  VAL   D CG1   1 
ATOM   6830  C  CG2   . VAL   F 3 181 ? 13.465  97.244  -81.227 1.00 65.77  ? 474  VAL   D CG2   1 
ATOM   6831  N  N     . PHE   F 3 182 ? 11.424  100.110 -84.347 1.00 65.12  ? 475  PHE   D N     1 
ATOM   6832  C  CA    . PHE   F 3 182 ? 10.420  100.838 -85.121 1.00 65.27  ? 475  PHE   D CA    1 
ATOM   6833  C  C     . PHE   F 3 182 ? 10.277  100.213 -86.511 1.00 67.21  ? 475  PHE   D C     1 
ATOM   6834  O  O     . PHE   F 3 182 ? 9.176   99.875  -86.944 1.00 60.95  ? 475  PHE   D O     1 
ATOM   6835  C  CB    . PHE   F 3 182 ? 10.780  102.324 -85.261 1.00 55.54  ? 475  PHE   D CB    1 
ATOM   6836  C  CG    . PHE   F 3 182 ? 10.596  103.175 -84.030 1.00 50.95  ? 475  PHE   D CG    1 
ATOM   6837  C  CD1   . PHE   F 3 182 ? 10.180  102.628 -82.824 1.00 49.56  ? 475  PHE   D CD1   1 
ATOM   6838  C  CD2   . PHE   F 3 182 ? 10.866  104.535 -84.074 1.00 48.26  ? 475  PHE   D CD2   1 
ATOM   6839  C  CE1   . PHE   F 3 182 ? 10.012  103.422 -81.699 1.00 49.66  ? 475  PHE   D CE1   1 
ATOM   6840  C  CE2   . PHE   F 3 182 ? 10.709  105.326 -82.944 1.00 48.10  ? 475  PHE   D CE2   1 
ATOM   6841  C  CZ    . PHE   F 3 182 ? 10.271  104.769 -81.760 1.00 47.80  ? 475  PHE   D CZ    1 
ATOM   6842  N  N     . ARG   F 3 183 ? 11.411  100.061 -87.199 1.00 73.04  ? 476  ARG   D N     1 
ATOM   6843  C  CA    . ARG   F 3 183 ? 11.442  99.446  -88.514 1.00 79.30  ? 476  ARG   D CA    1 
ATOM   6844  C  C     . ARG   F 3 183 ? 10.717  98.097  -88.456 1.00 75.39  ? 476  ARG   D C     1 
ATOM   6845  O  O     . ARG   F 3 183 ? 9.824   97.844  -89.257 1.00 78.59  ? 476  ARG   D O     1 
ATOM   6846  C  CB    . ARG   F 3 183 ? 12.896  99.340  -88.995 1.00 82.05  ? 476  ARG   D CB    1 
ATOM   6847  C  CG    . ARG   F 3 183 ? 13.052  99.326  -90.510 1.00 87.15  ? 476  ARG   D CG    1 
ATOM   6848  C  CD    . ARG   F 3 183 ? 14.423  98.862  -90.970 1.00 89.17  ? 476  ARG   D CD    1 
ATOM   6849  N  NE    . ARG   F 3 183 ? 14.750  97.511  -90.514 1.00 98.49  ? 476  ARG   D NE    1 
ATOM   6850  C  CZ    . ARG   F 3 183 ? 14.092  96.398  -90.846 1.00 93.49  ? 476  ARG   D CZ    1 
ATOM   6851  N  NH1   . ARG   F 3 183 ? 13.190  96.408  -91.813 1.00 97.79  ? 476  ARG   D NH1   1 
ATOM   6852  N  NH2   . ARG   F 3 183 ? 14.356  95.262  -90.220 1.00 82.58  ? 476  ARG   D NH2   1 
ATOM   6853  N  N     . LEU   F 3 184 ? 11.050  97.260  -87.465 1.00 76.27  ? 477  LEU   D N     1 
ATOM   6854  C  CA    . LEU   F 3 184 ? 10.587  95.878  -87.414 1.00 73.08  ? 477  LEU   D CA    1 
ATOM   6855  C  C     . LEU   F 3 184 ? 9.097   95.775  -87.091 1.00 72.40  ? 477  LEU   D C     1 
ATOM   6856  O  O     . LEU   F 3 184 ? 8.508   94.725  -87.331 1.00 78.02  ? 477  LEU   D O     1 
ATOM   6857  C  CB    . LEU   F 3 184 ? 11.411  95.094  -86.382 1.00 77.47  ? 477  LEU   D CB    1 
ATOM   6858  C  CG    . LEU   F 3 184 ? 12.607  94.313  -86.932 1.00 84.98  ? 477  LEU   D CG    1 
ATOM   6859  C  CD1   . LEU   F 3 184 ? 13.572  93.935  -85.819 1.00 84.13  ? 477  LEU   D CD1   1 
ATOM   6860  C  CD2   . LEU   F 3 184 ? 12.152  93.059  -87.675 1.00 85.27  ? 477  LEU   D CD2   1 
ATOM   6861  N  N     . ALA   F 3 185 ? 8.489   96.829  -86.531 1.00 70.92  ? 478  ALA   D N     1 
ATOM   6862  C  CA    . ALA   F 3 185 ? 7.101   96.767  -86.093 1.00 73.14  ? 478  ALA   D CA    1 
ATOM   6863  C  C     . ALA   F 3 185 ? 6.163   97.477  -87.069 1.00 73.59  ? 478  ALA   D C     1 
ATOM   6864  O  O     . ALA   F 3 185 ? 4.951   97.279  -87.007 1.00 71.70  ? 478  ALA   D O     1 
ATOM   6865  C  CB    . ALA   F 3 185 ? 6.978   97.365  -84.715 1.00 73.21  ? 478  ALA   D CB    1 
ATOM   6866  N  N     . GLY   F 3 186 ? 6.719   98.328  -87.938 1.00 73.46  ? 479  GLY   D N     1 
ATOM   6867  C  CA    . GLY   F 3 186 ? 5.929   99.091  -88.890 1.00 75.02  ? 479  GLY   D CA    1 
ATOM   6868  C  C     . GLY   F 3 186 ? 5.876   100.575 -88.540 1.00 74.24  ? 479  GLY   D C     1 
ATOM   6869  O  O     . GLY   F 3 186 ? 5.817   101.419 -89.427 1.00 80.20  ? 479  GLY   D O     1 
ATOM   6870  N  N     . HIS   F 3 187 ? 5.916   100.882 -87.243 1.00 72.70  ? 480  HIS   D N     1 
ATOM   6871  C  CA    . HIS   F 3 187 ? 5.548   102.199 -86.753 1.00 69.50  ? 480  HIS   D CA    1 
ATOM   6872  C  C     . HIS   F 3 187 ? 6.304   102.513 -85.466 1.00 69.20  ? 480  HIS   D C     1 
ATOM   6873  O  O     . HIS   F 3 187 ? 6.681   101.591 -84.748 1.00 62.47  ? 480  HIS   D O     1 
ATOM   6874  C  CB    . HIS   F 3 187 ? 4.036   102.235 -86.495 1.00 70.75  ? 480  HIS   D CB    1 
ATOM   6875  C  CG    . HIS   F 3 187 ? 3.527   101.180 -85.552 1.00 70.68  ? 480  HIS   D CG    1 
ATOM   6876  N  ND1   . HIS   F 3 187 ? 3.227   101.406 -84.222 1.00 70.13  ? 480  HIS   D ND1   1 
ATOM   6877  C  CD2   . HIS   F 3 187 ? 3.292   99.858  -85.784 1.00 65.28  ? 480  HIS   D CD2   1 
ATOM   6878  C  CE1   . HIS   F 3 187 ? 2.797   100.277 -83.666 1.00 63.90  ? 480  HIS   D CE1   1 
ATOM   6879  N  NE2   . HIS   F 3 187 ? 2.827   99.306  -84.619 1.00 65.95  ? 480  HIS   D NE2   1 
ATOM   6880  N  N     . PRO   F 3 188 ? 6.547   103.808 -85.133 1.00 70.52  ? 481  PRO   D N     1 
ATOM   6881  C  CA    . PRO   F 3 188 ? 6.925   104.212 -83.774 1.00 62.47  ? 481  PRO   D CA    1 
ATOM   6882  C  C     . PRO   F 3 188 ? 5.958   103.782 -82.668 1.00 52.95  ? 481  PRO   D C     1 
ATOM   6883  O  O     . PRO   F 3 188 ? 4.787   103.504 -82.932 1.00 55.12  ? 481  PRO   D O     1 
ATOM   6884  C  CB    . PRO   F 3 188 ? 6.974   105.756 -83.819 1.00 65.04  ? 481  PRO   D CB    1 
ATOM   6885  C  CG    . PRO   F 3 188 ? 6.338   106.140 -85.140 1.00 73.20  ? 481  PRO   D CG    1 
ATOM   6886  C  CD    . PRO   F 3 188 ? 6.566   104.953 -86.059 1.00 72.79  ? 481  PRO   D CD    1 
ATOM   6887  N  N     . PHE   F 3 189 ? 6.489   103.712 -81.436 1.00 46.16  ? 482  PHE   D N     1 
ATOM   6888  C  CA    . PHE   F 3 189 ? 5.722   103.508 -80.213 1.00 44.27  ? 482  PHE   D CA    1 
ATOM   6889  C  C     . PHE   F 3 189 ? 6.667   103.655 -79.020 1.00 41.46  ? 482  PHE   D C     1 
ATOM   6890  O  O     . PHE   F 3 189 ? 7.877   103.807 -79.207 1.00 38.84  ? 482  PHE   D O     1 
ATOM   6891  C  CB    . PHE   F 3 189 ? 4.999   102.153 -80.194 1.00 46.21  ? 482  PHE   D CB    1 
ATOM   6892  C  CG    . PHE   F 3 189 ? 5.895   100.938 -80.156 1.00 50.71  ? 482  PHE   D CG    1 
ATOM   6893  C  CD1   . PHE   F 3 189 ? 6.587   100.522 -81.286 1.00 50.96  ? 482  PHE   D CD1   1 
ATOM   6894  C  CD2   . PHE   F 3 189 ? 6.064   100.219 -78.979 1.00 51.81  ? 482  PHE   D CD2   1 
ATOM   6895  C  CE1   . PHE   F 3 189 ? 7.412   99.408  -81.243 1.00 52.14  ? 482  PHE   D CE1   1 
ATOM   6896  C  CE2   . PHE   F 3 189 ? 6.889   99.106  -78.938 1.00 49.59  ? 482  PHE   D CE2   1 
ATOM   6897  C  CZ    . PHE   F 3 189 ? 7.565   98.706  -80.068 1.00 52.73  ? 482  PHE   D CZ    1 
ATOM   6898  N  N     . ASN   F 3 190 ? 6.109   103.632 -77.800 1.00 38.59  ? 483  ASN   D N     1 
ATOM   6899  C  CA    . ASN   F 3 190 ? 6.932   103.691 -76.599 1.00 41.72  ? 483  ASN   D CA    1 
ATOM   6900  C  C     . ASN   F 3 190 ? 7.380   102.276 -76.202 1.00 44.18  ? 483  ASN   D C     1 
ATOM   6901  O  O     . ASN   F 3 190 ? 6.565   101.483 -75.726 1.00 42.65  ? 483  ASN   D O     1 
ATOM   6902  C  CB    . ASN   F 3 190 ? 6.189   104.401 -75.468 1.00 39.40  ? 483  ASN   D CB    1 
ATOM   6903  C  CG    . ASN   F 3 190 ? 7.127   104.777 -74.349 1.00 39.32  ? 483  ASN   D CG    1 
ATOM   6904  O  OD1   . ASN   F 3 190 ? 8.279   104.352 -74.358 1.00 38.26  ? 483  ASN   D OD1   1 
ATOM   6905  N  ND2   . ASN   F 3 190 ? 6.653   105.551 -73.388 1.00 34.48  ? 483  ASN   D ND2   1 
ATOM   6906  N  N     . LEU   F 3 191 ? 8.675   101.956 -76.409 1.00 45.15  ? 484  LEU   D N     1 
ATOM   6907  C  CA    . LEU   F 3 191 ? 9.240   100.661 -76.031 1.00 44.36  ? 484  LEU   D CA    1 
ATOM   6908  C  C     . LEU   F 3 191 ? 9.204   100.466 -74.510 1.00 41.87  ? 484  LEU   D C     1 
ATOM   6909  O  O     . LEU   F 3 191 ? 9.128   99.336  -74.057 1.00 46.40  ? 484  LEU   D O     1 
ATOM   6910  C  CB    . LEU   F 3 191 ? 10.675  100.522 -76.564 1.00 47.24  ? 484  LEU   D CB    1 
ATOM   6911  C  CG    . LEU   F 3 191 ? 10.819  100.092 -78.032 1.00 47.47  ? 484  LEU   D CG    1 
ATOM   6912  C  CD1   . LEU   F 3 191 ? 10.362  101.193 -78.979 1.00 51.29  ? 484  LEU   D CD1   1 
ATOM   6913  C  CD2   . LEU   F 3 191 ? 12.257  99.709  -78.367 1.00 43.05  ? 484  LEU   D CD2   1 
ATOM   6914  N  N     . ASN   F 3 192 ? 9.208   101.563 -73.739 1.00 43.63  ? 485  ASN   D N     1 
ATOM   6915  C  CA    . ASN   F 3 192 ? 9.122   101.550 -72.284 1.00 45.31  ? 485  ASN   D CA    1 
ATOM   6916  C  C     . ASN   F 3 192 ? 7.694   101.373 -71.759 1.00 44.96  ? 485  ASN   D C     1 
ATOM   6917  O  O     . ASN   F 3 192 ? 7.496   101.367 -70.545 1.00 44.16  ? 485  ASN   D O     1 
ATOM   6918  C  CB    . ASN   F 3 192 ? 9.592   102.875 -71.675 1.00 45.55  ? 485  ASN   D CB    1 
ATOM   6919  C  CG    . ASN   F 3 192 ? 11.044  103.186 -71.932 1.00 53.37  ? 485  ASN   D CG    1 
ATOM   6920  O  OD1   . ASN   F 3 192 ? 11.907  102.328 -71.740 1.00 58.28  ? 485  ASN   D OD1   1 
ATOM   6921  N  ND2   . ASN   F 3 192 ? 11.314  104.416 -72.343 1.00 58.60  ? 485  ASN   D ND2   1 
ATOM   6922  N  N     . SER   F 3 193 ? 6.693   101.327 -72.645 1.00 45.64  ? 486  SER   D N     1 
ATOM   6923  C  CA    . SER   F 3 193 ? 5.312   101.105 -72.233 1.00 51.00  ? 486  SER   D CA    1 
ATOM   6924  C  C     . SER   F 3 193 ? 4.979   99.622  -72.393 1.00 53.52  ? 486  SER   D C     1 
ATOM   6925  O  O     . SER   F 3 193 ? 4.934   99.111  -73.519 1.00 49.47  ? 486  SER   D O     1 
ATOM   6926  C  CB    . SER   F 3 193 ? 4.347   101.978 -73.015 1.00 55.03  ? 486  SER   D CB    1 
ATOM   6927  O  OG    . SER   F 3 193 ? 3.004   101.514 -72.890 1.00 54.47  ? 486  SER   D OG    1 
ATOM   6928  N  N     . ARG   F 3 194 ? 4.767   98.930  -71.260 1.00 53.42  ? 487  ARG   D N     1 
ATOM   6929  C  CA    . ARG   F 3 194 ? 4.385   97.524  -71.316 1.00 50.65  ? 487  ARG   D CA    1 
ATOM   6930  C  C     . ARG   F 3 194 ? 3.013   97.399  -71.992 1.00 51.60  ? 487  ARG   D C     1 
ATOM   6931  O  O     . ARG   F 3 194 ? 2.802   96.469  -72.757 1.00 53.01  ? 487  ARG   D O     1 
ATOM   6932  C  CB    . ARG   F 3 194 ? 4.485   96.858  -69.936 1.00 46.18  ? 487  ARG   D CB    1 
ATOM   6933  C  CG    . ARG   F 3 194 ? 3.608   97.448  -68.835 1.00 48.16  ? 487  ARG   D CG    1 
ATOM   6934  C  CD    . ARG   F 3 194 ? 2.197   96.879  -68.759 1.00 45.83  ? 487  ARG   D CD    1 
ATOM   6935  N  NE    . ARG   F 3 194 ? 2.172   95.426  -68.878 1.00 48.97  ? 487  ARG   D NE    1 
ATOM   6936  C  CZ    . ARG   F 3 194 ? 1.345   94.741  -69.660 1.00 52.37  ? 487  ARG   D CZ    1 
ATOM   6937  N  NH1   . ARG   F 3 194 ? 0.186   95.273  -70.026 1.00 55.63  ? 487  ARG   D NH1   1 
ATOM   6938  N  NH2   . ARG   F 3 194 ? 1.683   93.523  -70.057 1.00 49.75  ? 487  ARG   D NH2   1 
ATOM   6939  N  N     . ASP   F 3 195 ? 2.102   98.364  -71.781 1.00 52.21  ? 488  ASP   D N     1 
ATOM   6940  C  CA    . ASP   F 3 195 ? 0.800   98.313  -72.439 1.00 54.91  ? 488  ASP   D CA    1 
ATOM   6941  C  C     . ASP   F 3 195 ? 0.967   98.304  -73.960 1.00 53.85  ? 488  ASP   D C     1 
ATOM   6942  O  O     . ASP   F 3 195 ? 0.338   97.489  -74.620 1.00 54.09  ? 488  ASP   D O     1 
ATOM   6943  C  CB    . ASP   F 3 195 ? -0.130  99.454  -72.013 1.00 52.65  ? 488  ASP   D CB    1 
ATOM   6944  C  CG    . ASP   F 3 195 ? -0.791  99.277  -70.659 1.00 54.78  ? 488  ASP   D CG    1 
ATOM   6945  O  OD1   . ASP   F 3 195 ? -0.899  98.117  -70.193 1.00 56.21  ? 488  ASP   D OD1   1 
ATOM   6946  O  OD2   . ASP   F 3 195 ? -1.170  100.312 -70.068 1.00 59.88  ? 488  ASP   D OD2   1 
ATOM   6947  N  N     . GLN   F 3 196 ? 1.811   99.191  -74.516 1.00 60.16  ? 489  GLN   D N     1 
ATOM   6948  C  CA    . GLN   F 3 196 ? 1.947   99.328  -75.966 1.00 58.27  ? 489  GLN   D CA    1 
ATOM   6949  C  C     . GLN   F 3 196 ? 2.755   98.168  -76.549 1.00 60.74  ? 489  GLN   D C     1 
ATOM   6950  O  O     . GLN   F 3 196 ? 2.546   97.799  -77.707 1.00 59.67  ? 489  GLN   D O     1 
ATOM   6951  C  CB    . GLN   F 3 196 ? 2.604   100.656 -76.356 1.00 57.96  ? 489  GLN   D CB    1 
ATOM   6952  C  CG    . GLN   F 3 196 ? 1.807   101.899 -75.965 1.00 57.75  ? 489  GLN   D CG    1 
ATOM   6953  C  CD    . GLN   F 3 196 ? 2.559   103.178 -76.262 1.00 58.86  ? 489  GLN   D CD    1 
ATOM   6954  O  OE1   . GLN   F 3 196 ? 3.111   103.347 -77.350 1.00 61.54  ? 489  GLN   D OE1   1 
ATOM   6955  N  NE2   . GLN   F 3 196 ? 2.601   104.079 -75.290 1.00 49.36  ? 489  GLN   D NE2   1 
ATOM   6956  N  N     . LEU   F 3 197 ? 3.689   97.616  -75.754 1.00 65.71  ? 490  LEU   D N     1 
ATOM   6957  C  CA    . LEU   F 3 197 ? 4.469   96.444  -76.147 1.00 62.26  ? 490  LEU   D CA    1 
ATOM   6958  C  C     . LEU   F 3 197 ? 3.586   95.203  -76.264 1.00 57.90  ? 490  LEU   D C     1 
ATOM   6959  O  O     . LEU   F 3 197 ? 3.866   94.337  -77.095 1.00 51.69  ? 490  LEU   D O     1 
ATOM   6960  C  CB    . LEU   F 3 197 ? 5.558   96.174  -75.104 1.00 62.32  ? 490  LEU   D CB    1 
ATOM   6961  C  CG    . LEU   F 3 197 ? 6.996   96.393  -75.551 1.00 65.48  ? 490  LEU   D CG    1 
ATOM   6962  C  CD1   . LEU   F 3 197 ? 7.950   95.888  -74.477 1.00 68.98  ? 490  LEU   D CD1   1 
ATOM   6963  C  CD2   . LEU   F 3 197 ? 7.276   95.719  -76.887 1.00 62.51  ? 490  LEU   D CD2   1 
ATOM   6964  N  N     . GLU   F 3 198 ? 2.596   95.099  -75.356 1.00 57.56  ? 491  GLU   D N     1 
ATOM   6965  C  CA    . GLU   F 3 198 ? 1.624   94.010  -75.322 1.00 61.35  ? 491  GLU   D CA    1 
ATOM   6966  C  C     . GLU   F 3 198 ? 0.861   93.972  -76.648 1.00 64.92  ? 491  GLU   D C     1 
ATOM   6967  O  O     . GLU   F 3 198 ? 0.864   92.944  -77.328 1.00 61.54  ? 491  GLU   D O     1 
ATOM   6968  C  CB    . GLU   F 3 198 ? 0.666   94.202  -74.136 1.00 61.54  ? 491  GLU   D CB    1 
ATOM   6969  C  CG    . GLU   F 3 198 ? -0.389  93.111  -73.983 1.00 59.13  ? 491  GLU   D CG    1 
ATOM   6970  C  CD    . GLU   F 3 198 ? -1.411  93.353  -72.883 1.00 58.65  ? 491  GLU   D CD    1 
ATOM   6971  O  OE1   . GLU   F 3 198 ? -1.282  94.340  -72.133 1.00 51.60  ? 491  GLU   D OE1   1 
ATOM   6972  O  OE2   . GLU   F 3 198 ? -2.347  92.547  -72.778 1.00 72.64  ? 491  GLU   D OE2   1 
ATOM   6973  N  N     . ARG   F 3 199 ? 0.242   95.117  -76.994 1.00 69.12  ? 492  ARG   D N     1 
ATOM   6974  C  CA    . ARG   F 3 199 ? -0.545  95.301  -78.209 1.00 69.69  ? 492  ARG   D CA    1 
ATOM   6975  C  C     . ARG   F 3 199 ? 0.293   95.036  -79.454 1.00 64.27  ? 492  ARG   D C     1 
ATOM   6976  O  O     . ARG   F 3 199 ? -0.206  94.466  -80.411 1.00 77.34  ? 492  ARG   D O     1 
ATOM   6977  C  CB    . ARG   F 3 199 ? -1.119  96.719  -78.280 1.00 72.29  ? 492  ARG   D CB    1 
ATOM   6978  C  CG    . ARG   F 3 199 ? -2.254  96.972  -77.298 1.00 80.06  ? 492  ARG   D CG    1 
ATOM   6979  C  CD    . ARG   F 3 199 ? -2.332  98.428  -76.878 1.00 86.20  ? 492  ARG   D CD    1 
ATOM   6980  N  NE    . ARG   F 3 199 ? -3.476  98.683  -76.013 1.00 95.15  ? 492  ARG   D NE    1 
ATOM   6981  C  CZ    . ARG   F 3 199 ? -3.614  99.746  -75.221 1.00 106.18 ? 492  ARG   D CZ    1 
ATOM   6982  N  NH1   . ARG   F 3 199 ? -2.553  100.340 -74.696 1.00 99.91  ? 492  ARG   D NH1   1 
ATOM   6983  N  NH2   . ARG   F 3 199 ? -4.826  100.190 -74.920 1.00 113.08 ? 492  ARG   D NH2   1 
ATOM   6984  N  N     . VAL   F 3 200 ? 1.561   95.446  -79.445 1.00 62.55  ? 493  VAL   D N     1 
ATOM   6985  C  CA    . VAL   F 3 200 ? 2.405   95.311  -80.621 1.00 61.86  ? 493  VAL   D CA    1 
ATOM   6986  C  C     . VAL   F 3 200 ? 2.847   93.860  -80.798 1.00 63.71  ? 493  VAL   D C     1 
ATOM   6987  O  O     . VAL   F 3 200 ? 2.843   93.356  -81.919 1.00 65.65  ? 493  VAL   D O     1 
ATOM   6988  C  CB    . VAL   F 3 200 ? 3.609   96.265  -80.542 1.00 62.53  ? 493  VAL   D CB    1 
ATOM   6989  C  CG1   . VAL   F 3 200 ? 4.695   95.925  -81.554 1.00 63.50  ? 493  VAL   D CG1   1 
ATOM   6990  C  CG2   . VAL   F 3 200 ? 3.161   97.710  -80.686 1.00 65.29  ? 493  VAL   D CG2   1 
ATOM   6991  N  N     . LEU   F 3 201 ? 3.244   93.202  -79.700 1.00 69.74  ? 494  LEU   D N     1 
ATOM   6992  C  CA    . LEU   F 3 201 ? 3.867   91.884  -79.769 1.00 71.64  ? 494  LEU   D CA    1 
ATOM   6993  C  C     . LEU   F 3 201 ? 2.821   90.794  -80.007 1.00 69.92  ? 494  LEU   D C     1 
ATOM   6994  O  O     . LEU   F 3 201 ? 3.081   89.830  -80.724 1.00 64.02  ? 494  LEU   D O     1 
ATOM   6995  C  CB    . LEU   F 3 201 ? 4.638   91.609  -78.471 1.00 74.39  ? 494  LEU   D CB    1 
ATOM   6996  C  CG    . LEU   F 3 201 ? 5.996   92.301  -78.327 1.00 74.20  ? 494  LEU   D CG    1 
ATOM   6997  C  CD1   . LEU   F 3 201 ? 6.560   92.097  -76.928 1.00 74.35  ? 494  LEU   D CD1   1 
ATOM   6998  C  CD2   . LEU   F 3 201 ? 6.990   91.800  -79.368 1.00 72.60  ? 494  LEU   D CD2   1 
ATOM   6999  N  N     . PHE   F 3 202 ? 1.642   90.950  -79.398 1.00 73.79  ? 495  PHE   D N     1 
ATOM   7000  C  CA    . PHE   F 3 202 ? 0.678   89.865  -79.312 1.00 78.88  ? 495  PHE   D CA    1 
ATOM   7001  C  C     . PHE   F 3 202 ? -0.507  90.083  -80.254 1.00 83.84  ? 495  PHE   D C     1 
ATOM   7002  O  O     . PHE   F 3 202 ? -1.049  89.106  -80.764 1.00 85.33  ? 495  PHE   D O     1 
ATOM   7003  C  CB    . PHE   F 3 202 ? 0.223   89.694  -77.860 1.00 79.84  ? 495  PHE   D CB    1 
ATOM   7004  C  CG    . PHE   F 3 202 ? 1.331   89.409  -76.875 1.00 79.78  ? 495  PHE   D CG    1 
ATOM   7005  C  CD1   . PHE   F 3 202 ? 2.395   88.583  -77.210 1.00 79.53  ? 495  PHE   D CD1   1 
ATOM   7006  C  CD2   . PHE   F 3 202 ? 1.294   89.945  -75.596 1.00 80.35  ? 495  PHE   D CD2   1 
ATOM   7007  C  CE1   . PHE   F 3 202 ? 3.406   88.317  -76.297 1.00 78.00  ? 495  PHE   D CE1   1 
ATOM   7008  C  CE2   . PHE   F 3 202 ? 2.305   89.676  -74.685 1.00 77.68  ? 495  PHE   D CE2   1 
ATOM   7009  C  CZ    . PHE   F 3 202 ? 3.356   88.859  -75.035 1.00 77.20  ? 495  PHE   D CZ    1 
ATOM   7010  N  N     . ASP   F 3 203 ? -0.915  91.347  -80.463 1.00 84.51  ? 496  ASP   D N     1 
ATOM   7011  C  CA    . ASP   F 3 203 ? -1.997  91.671  -81.383 1.00 79.83  ? 496  ASP   D CA    1 
ATOM   7012  C  C     . ASP   F 3 203 ? -1.441  91.805  -82.803 1.00 82.39  ? 496  ASP   D C     1 
ATOM   7013  O  O     . ASP   F 3 203 ? -1.740  90.973  -83.653 1.00 92.13  ? 496  ASP   D O     1 
ATOM   7014  C  CB    . ASP   F 3 203 ? -2.770  92.916  -80.933 1.00 77.01  ? 496  ASP   D CB    1 
ATOM   7015  C  CG    . ASP   F 3 203 ? -3.497  92.763  -79.606 1.00 78.35  ? 496  ASP   D CG    1 
ATOM   7016  O  OD1   . ASP   F 3 203 ? -3.663  91.612  -79.157 1.00 76.75  ? 496  ASP   D OD1   1 
ATOM   7017  O  OD2   . ASP   F 3 203 ? -3.889  93.802  -79.023 1.00 77.39  ? 496  ASP   D OD2   1 
ATOM   7018  N  N     . GLU   F 3 204 ? -0.615  92.829  -83.055 1.00 83.31  ? 497  GLU   D N     1 
ATOM   7019  C  CA    . GLU   F 3 204 ? -0.192  93.174  -84.409 1.00 78.35  ? 497  GLU   D CA    1 
ATOM   7020  C  C     . GLU   F 3 204 ? 0.711   92.087  -84.995 1.00 79.21  ? 497  GLU   D C     1 
ATOM   7021  O  O     . GLU   F 3 204 ? 0.485   91.624  -86.117 1.00 78.20  ? 497  GLU   D O     1 
ATOM   7022  C  CB    . GLU   F 3 204 ? 0.563   94.507  -84.439 1.00 74.66  ? 497  GLU   D CB    1 
ATOM   7023  C  CG    . GLU   F 3 204 ? -0.247  95.708  -83.969 1.00 72.78  ? 497  GLU   D CG    1 
ATOM   7024  C  CD    . GLU   F 3 204 ? 0.583   96.977  -83.855 1.00 73.55  ? 497  GLU   D CD    1 
ATOM   7025  O  OE1   . GLU   F 3 204 ? 1.774   96.929  -84.253 1.00 71.35  ? 497  GLU   D OE1   1 
ATOM   7026  O  OE2   . GLU   F 3 204 ? 0.055   98.004  -83.361 1.00 66.17  ? 497  GLU   D OE2   1 
ATOM   7027  N  N     . LEU   F 3 205 ? 1.756   91.710  -84.246 1.00 76.82  ? 498  LEU   D N     1 
ATOM   7028  C  CA    . LEU   F 3 205 ? 2.710   90.711  -84.711 1.00 77.77  ? 498  LEU   D CA    1 
ATOM   7029  C  C     . LEU   F 3 205 ? 2.216   89.303  -84.373 1.00 77.65  ? 498  LEU   D C     1 
ATOM   7030  O  O     . LEU   F 3 205 ? 2.768   88.328  -84.880 1.00 70.87  ? 498  LEU   D O     1 
ATOM   7031  C  CB    . LEU   F 3 205 ? 4.076   90.982  -84.076 1.00 78.58  ? 498  LEU   D CB    1 
ATOM   7032  C  CG    . LEU   F 3 205 ? 4.738   92.307  -84.455 1.00 79.35  ? 498  LEU   D CG    1 
ATOM   7033  C  CD1   . LEU   F 3 205 ? 6.086   92.440  -83.763 1.00 78.98  ? 498  LEU   D CD1   1 
ATOM   7034  C  CD2   . LEU   F 3 205 ? 4.897   92.433  -85.965 1.00 76.90  ? 498  LEU   D CD2   1 
ATOM   7035  N  N     . GLY   F 3 206 ? 1.214   89.213  -83.483 1.00 78.46  ? 499  GLY   D N     1 
ATOM   7036  C  CA    . GLY   F 3 206 ? 0.454   87.991  -83.258 1.00 84.00  ? 499  GLY   D CA    1 
ATOM   7037  C  C     . GLY   F 3 206 ? 1.232   86.892  -82.532 1.00 87.06  ? 499  GLY   D C     1 
ATOM   7038  O  O     . GLY   F 3 206 ? 0.861   85.726  -82.631 1.00 82.47  ? 499  GLY   D O     1 
ATOM   7039  N  N     . LEU   F 3 207 ? 2.284   87.264  -81.786 1.00 91.21  ? 500  LEU   D N     1 
ATOM   7040  C  CA    . LEU   F 3 207 ? 3.174   86.300  -81.149 1.00 87.64  ? 500  LEU   D CA    1 
ATOM   7041  C  C     . LEU   F 3 207 ? 2.483   85.638  -79.958 1.00 85.03  ? 500  LEU   D C     1 
ATOM   7042  O  O     . LEU   F 3 207 ? 1.641   86.256  -79.308 1.00 81.19  ? 500  LEU   D O     1 
ATOM   7043  C  CB    . LEU   F 3 207 ? 4.447   87.020  -80.690 1.00 86.07  ? 500  LEU   D CB    1 
ATOM   7044  C  CG    . LEU   F 3 207 ? 5.279   87.664  -81.795 1.00 85.90  ? 500  LEU   D CG    1 
ATOM   7045  C  CD1   . LEU   F 3 207 ? 6.542   88.296  -81.225 1.00 86.63  ? 500  LEU   D CD1   1 
ATOM   7046  C  CD2   . LEU   F 3 207 ? 5.628   86.645  -82.870 1.00 87.61  ? 500  LEU   D CD2   1 
ATOM   7047  N  N     . PRO   F 3 208 ? 2.829   84.370  -79.624 1.00 86.85  ? 501  PRO   D N     1 
ATOM   7048  C  CA    . PRO   F 3 208 ? 2.178   83.661  -78.520 1.00 86.99  ? 501  PRO   D CA    1 
ATOM   7049  C  C     . PRO   F 3 208 ? 2.419   84.340  -77.169 1.00 86.94  ? 501  PRO   D C     1 
ATOM   7050  O  O     . PRO   F 3 208 ? 3.537   84.763  -76.867 1.00 87.06  ? 501  PRO   D O     1 
ATOM   7051  C  CB    . PRO   F 3 208 ? 2.779   82.243  -78.574 1.00 86.86  ? 501  PRO   D CB    1 
ATOM   7052  C  CG    . PRO   F 3 208 ? 4.085   82.401  -79.329 1.00 87.06  ? 501  PRO   D CG    1 
ATOM   7053  C  CD    . PRO   F 3 208 ? 3.858   83.551  -80.289 1.00 86.38  ? 501  PRO   D CD    1 
ATOM   7054  N  N     . ALA   F 3 209 ? 1.344   84.425  -76.371 1.00 88.39  ? 502  ALA   D N     1 
ATOM   7055  C  CA    . ALA   F 3 209 ? 1.323   85.141  -75.103 1.00 91.34  ? 502  ALA   D CA    1 
ATOM   7056  C  C     . ALA   F 3 209 ? 1.338   84.149  -73.939 1.00 89.73  ? 502  ALA   D C     1 
ATOM   7057  O  O     . ALA   F 3 209 ? 0.289   83.701  -73.483 1.00 81.25  ? 502  ALA   D O     1 
ATOM   7058  C  CB    . ALA   F 3 209 ? 0.103   86.029  -75.052 1.00 91.77  ? 502  ALA   D CB    1 
ATOM   7059  N  N     . ILE   F 3 210 ? 2.539   83.865  -73.427 1.00 95.88  ? 503  ILE   D N     1 
ATOM   7060  C  CA    . ILE   F 3 210 ? 2.791   82.673  -72.631 1.00 95.19  ? 503  ILE   D CA    1 
ATOM   7061  C  C     . ILE   F 3 210 ? 2.347   82.863  -71.177 1.00 91.59  ? 503  ILE   D C     1 
ATOM   7062  O  O     . ILE   F 3 210 ? 1.895   81.905  -70.557 1.00 87.21  ? 503  ILE   D O     1 
ATOM   7063  C  CB    . ILE   F 3 210 ? 4.275   82.270  -72.781 1.00 97.88  ? 503  ILE   D CB    1 
ATOM   7064  C  CG1   . ILE   F 3 210 ? 4.482   81.530  -74.107 1.00 102.71 ? 503  ILE   D CG1   1 
ATOM   7065  C  CG2   . ILE   F 3 210 ? 4.780   81.461  -71.592 1.00 92.55  ? 503  ILE   D CG2   1 
ATOM   7066  C  CD1   . ILE   F 3 210 ? 5.908   81.519  -74.602 1.00 110.61 ? 503  ILE   D CD1   1 
ATOM   7067  N  N     . GLY   F 3 211 ? 2.457   84.083  -70.633 1.00 88.19  ? 504  GLY   D N     1 
ATOM   7068  C  CA    . GLY   F 3 211 ? 2.178   84.314  -69.222 1.00 80.52  ? 504  GLY   D CA    1 
ATOM   7069  C  C     . GLY   F 3 211 ? 1.248   85.501  -68.990 1.00 72.57  ? 504  GLY   D C     1 
ATOM   7070  O  O     . GLY   F 3 211 ? 0.998   86.282  -69.900 1.00 75.25  ? 504  GLY   D O     1 
ATOM   7071  N  N     . LYS   F 3 212 ? 0.740   85.618  -67.759 1.00 74.61  ? 505  LYS   D N     1 
ATOM   7072  C  CA    . LYS   F 3 212 ? -0.102  86.735  -67.357 1.00 79.13  ? 505  LYS   D CA    1 
ATOM   7073  C  C     . LYS   F 3 212 ? 0.655   87.615  -66.362 1.00 74.12  ? 505  LYS   D C     1 
ATOM   7074  O  O     . LYS   F 3 212 ? 1.655   87.184  -65.780 1.00 69.28  ? 505  LYS   D O     1 
ATOM   7075  C  CB    . LYS   F 3 212 ? -1.404  86.239  -66.718 1.00 92.12  ? 505  LYS   D CB    1 
ATOM   7076  C  CG    . LYS   F 3 212 ? -2.323  85.412  -67.622 1.00 100.73 ? 505  LYS   D CG    1 
ATOM   7077  C  CD    . LYS   F 3 212 ? -3.434  84.694  -66.847 1.00 107.05 ? 505  LYS   D CD    1 
ATOM   7078  C  CE    . LYS   F 3 212 ? -4.386  85.661  -66.105 1.00 106.01 ? 505  LYS   D CE    1 
ATOM   7079  N  NZ    . LYS   F 3 212 ? -5.020  86.641  -67.063 1.00 109.46 ? 505  LYS   D NZ    1 
ATOM   7080  N  N     . THR   F 3 213 ? 0.172   88.857  -66.191 1.00 67.86  ? 506  THR   D N     1 
ATOM   7081  C  CA    . THR   F 3 213 ? 0.688   89.751  -65.165 1.00 67.70  ? 506  THR   D CA    1 
ATOM   7082  C  C     . THR   F 3 213 ? -0.025  89.400  -63.866 1.00 71.79  ? 506  THR   D C     1 
ATOM   7083  O  O     . THR   F 3 213 ? -1.068  88.749  -63.898 1.00 71.82  ? 506  THR   D O     1 
ATOM   7084  C  CB    . THR   F 3 213 ? 0.555   91.241  -65.533 1.00 62.59  ? 506  THR   D CB    1 
ATOM   7085  O  OG1   . THR   F 3 213 ? -0.759  91.746  -65.288 1.00 60.10  ? 506  THR   D OG1   1 
ATOM   7086  C  CG2   . THR   F 3 213 ? 0.903   91.527  -66.977 1.00 61.28  ? 506  THR   D CG2   1 
ATOM   7087  N  N     . GLU   F 3 214 ? 0.539   89.855  -62.742 1.00 74.94  ? 507  GLU   D N     1 
ATOM   7088  C  CA    . GLU   F 3 214 ? 0.102   89.407  -61.432 1.00 75.90  ? 507  GLU   D CA    1 
ATOM   7089  C  C     . GLU   F 3 214 ? -1.322  89.867  -61.136 1.00 74.52  ? 507  GLU   D C     1 
ATOM   7090  O  O     . GLU   F 3 214 ? -2.155  89.043  -60.775 1.00 88.50  ? 507  GLU   D O     1 
ATOM   7091  C  CB    . GLU   F 3 214 ? 1.036   89.922  -60.338 1.00 79.43  ? 507  GLU   D CB    1 
ATOM   7092  C  CG    . GLU   F 3 214 ? 2.437   89.340  -60.394 1.00 78.31  ? 507  GLU   D CG    1 
ATOM   7093  C  CD    . GLU   F 3 214 ? 3.293   89.692  -59.185 1.00 82.04  ? 507  GLU   D CD    1 
ATOM   7094  O  OE1   . GLU   F 3 214 ? 2.743   90.255  -58.196 1.00 78.77  ? 507  GLU   D OE1   1 
ATOM   7095  O  OE2   . GLU   F 3 214 ? 4.509   89.413  -59.234 1.00 76.73  ? 507  GLU   D OE2   1 
ATOM   7096  N  N     . LYS   F 3 215 ? -1.586  91.170  -61.287 1.00 70.27  ? 508  LYS   D N     1 
ATOM   7097  C  CA    . LYS   F 3 215 ? -2.733  91.804  -60.653 1.00 75.41  ? 508  LYS   D CA    1 
ATOM   7098  C  C     . LYS   F 3 215 ? -3.720  92.400  -61.659 1.00 79.83  ? 508  LYS   D C     1 
ATOM   7099  O  O     . LYS   F 3 215 ? -4.884  92.591  -61.309 1.00 79.72  ? 508  LYS   D O     1 
ATOM   7100  C  CB    . LYS   F 3 215 ? -2.228  92.872  -59.678 1.00 77.86  ? 508  LYS   D CB    1 
ATOM   7101  C  CG    . LYS   F 3 215 ? -1.611  92.298  -58.407 1.00 82.96  ? 508  LYS   D CG    1 
ATOM   7102  C  CD    . LYS   F 3 215 ? -0.646  93.228  -57.709 1.00 84.09  ? 508  LYS   D CD    1 
ATOM   7103  C  CE    . LYS   F 3 215 ? -0.672  93.083  -56.203 1.00 86.05  ? 508  LYS   D CE    1 
ATOM   7104  N  NZ    . LYS   F 3 215 ? -1.858  93.754  -55.619 1.00 85.63  ? 508  LYS   D NZ    1 
ATOM   7105  N  N     . THR   F 3 216 ? -3.261  92.712  -62.880 1.00 80.67  ? 509  THR   D N     1 
ATOM   7106  C  CA    . THR   F 3 216 ? -4.093  93.354  -63.891 1.00 79.71  ? 509  THR   D CA    1 
ATOM   7107  C  C     . THR   F 3 216 ? -4.620  92.315  -64.882 1.00 77.56  ? 509  THR   D C     1 
ATOM   7108  O  O     . THR   F 3 216 ? -5.452  92.632  -65.729 1.00 71.14  ? 509  THR   D O     1 
ATOM   7109  C  CB    . THR   F 3 216 ? -3.327  94.470  -64.622 1.00 79.45  ? 509  THR   D CB    1 
ATOM   7110  O  OG1   . THR   F 3 216 ? -2.116  93.946  -65.174 1.00 72.41  ? 509  THR   D OG1   1 
ATOM   7111  C  CG2   . THR   F 3 216 ? -3.000  95.643  -63.724 1.00 77.99  ? 509  THR   D CG2   1 
ATOM   7112  N  N     . GLY   F 3 217 ? -4.126  91.076  -64.767 1.00 75.06  ? 510  GLY   D N     1 
ATOM   7113  C  CA    . GLY   F 3 217 ? -4.481  90.012  -65.685 1.00 73.86  ? 510  GLY   D CA    1 
ATOM   7114  C  C     . GLY   F 3 217 ? -4.389  90.458  -67.143 1.00 76.81  ? 510  GLY   D C     1 
ATOM   7115  O  O     . GLY   F 3 217 ? -5.376  90.416  -67.870 1.00 74.95  ? 510  GLY   D O     1 
ATOM   7116  N  N     . LYS   F 3 218 ? -3.193  90.887  -67.562 1.00 80.31  ? 511  LYS   D N     1 
ATOM   7117  C  CA    . LYS   F 3 218 ? -2.920  91.146  -68.967 1.00 74.51  ? 511  LYS   D CA    1 
ATOM   7118  C  C     . LYS   F 3 218 ? -1.844  90.171  -69.426 1.00 70.40  ? 511  LYS   D C     1 
ATOM   7119  O  O     . LYS   F 3 218 ? -1.275  89.462  -68.602 1.00 66.41  ? 511  LYS   D O     1 
ATOM   7120  C  CB    . LYS   F 3 218 ? -2.531  92.613  -69.164 1.00 78.87  ? 511  LYS   D CB    1 
ATOM   7121  C  CG    . LYS   F 3 218 ? -3.635  93.604  -68.830 1.00 86.69  ? 511  LYS   D CG    1 
ATOM   7122  C  CD    . LYS   F 3 218 ? -3.554  94.898  -69.597 1.00 97.06  ? 511  LYS   D CD    1 
ATOM   7123  C  CE    . LYS   F 3 218 ? -4.831  95.695  -69.455 1.00 100.86 ? 511  LYS   D CE    1 
ATOM   7124  N  NZ    . LYS   F 3 218 ? -4.651  97.078  -69.954 1.00 110.88 ? 511  LYS   D NZ    1 
ATOM   7125  N  N     . ARG   F 3 219 ? -1.590  90.118  -70.738 1.00 67.84  ? 512  ARG   D N     1 
ATOM   7126  C  CA    . ARG   F 3 219 ? -0.497  89.304  -71.253 1.00 73.52  ? 512  ARG   D CA    1 
ATOM   7127  C  C     . ARG   F 3 219 ? 0.838   89.969  -70.908 1.00 68.48  ? 512  ARG   D C     1 
ATOM   7128  O  O     . ARG   F 3 219 ? 0.999   91.177  -71.103 1.00 61.62  ? 512  ARG   D O     1 
ATOM   7129  C  CB    . ARG   F 3 219 ? -0.647  89.093  -72.762 1.00 75.90  ? 512  ARG   D CB    1 
ATOM   7130  C  CG    . ARG   F 3 219 ? -1.870  88.276  -73.163 1.00 79.21  ? 512  ARG   D CG    1 
ATOM   7131  C  CD    . ARG   F 3 219 ? -2.282  88.555  -74.599 1.00 78.24  ? 512  ARG   D CD    1 
ATOM   7132  N  NE    . ARG   F 3 219 ? -2.759  89.928  -74.751 1.00 71.86  ? 512  ARG   D NE    1 
ATOM   7133  C  CZ    . ARG   F 3 219 ? -2.989  90.523  -75.914 1.00 67.30  ? 512  ARG   D CZ    1 
ATOM   7134  N  NH1   . ARG   F 3 219 ? -2.657  89.924  -77.043 1.00 62.59  ? 512  ARG   D NH1   1 
ATOM   7135  N  NH2   . ARG   F 3 219 ? -3.539  91.723  -75.942 1.00 63.66  ? 512  ARG   D NH2   1 
ATOM   7136  N  N     . SER   F 3 220 ? 1.791   89.162  -70.413 1.00 63.59  ? 513  SER   D N     1 
ATOM   7137  C  CA    . SER   F 3 220 ? 3.021   89.670  -69.819 1.00 63.74  ? 513  SER   D CA    1 
ATOM   7138  C  C     . SER   F 3 220 ? 4.081   89.871  -70.899 1.00 61.16  ? 513  SER   D C     1 
ATOM   7139  O  O     . SER   F 3 220 ? 4.209   89.053  -71.808 1.00 61.58  ? 513  SER   D O     1 
ATOM   7140  C  CB    . SER   F 3 220 ? 3.538   88.763  -68.703 1.00 63.03  ? 513  SER   D CB    1 
ATOM   7141  O  OG    . SER   F 3 220 ? 4.733   89.277  -68.110 1.00 56.64  ? 513  SER   D OG    1 
ATOM   7142  N  N     . THR   F 3 221 ? 4.855   90.959  -70.743 1.00 58.36  ? 514  THR   D N     1 
ATOM   7143  C  CA    . THR   F 3 221 ? 5.965   91.295  -71.622 1.00 54.96  ? 514  THR   D CA    1 
ATOM   7144  C  C     . THR   F 3 221 ? 7.297   91.060  -70.899 1.00 56.15  ? 514  THR   D C     1 
ATOM   7145  O  O     . THR   F 3 221 ? 8.353   91.470  -71.388 1.00 53.68  ? 514  THR   D O     1 
ATOM   7146  C  CB    . THR   F 3 221 ? 5.788   92.735  -72.132 1.00 56.33  ? 514  THR   D CB    1 
ATOM   7147  O  OG1   . THR   F 3 221 ? 5.822   93.646  -71.032 1.00 50.92  ? 514  THR   D OG1   1 
ATOM   7148  C  CG2   . THR   F 3 221 ? 4.479   92.932  -72.868 1.00 55.83  ? 514  THR   D CG2   1 
ATOM   7149  N  N     . SER   F 3 222 ? 7.249   90.345  -69.764 1.00 57.11  ? 515  SER   D N     1 
ATOM   7150  C  CA    . SER   F 3 222 ? 8.417   90.140  -68.921 1.00 55.07  ? 515  SER   D CA    1 
ATOM   7151  C  C     . SER   F 3 222 ? 9.388   89.222  -69.641 1.00 54.11  ? 515  SER   D C     1 
ATOM   7152  O  O     . SER   F 3 222 ? 8.982   88.538  -70.572 1.00 58.39  ? 515  SER   D O     1 
ATOM   7153  C  CB    . SER   F 3 222 ? 8.040   89.591  -67.564 1.00 57.49  ? 515  SER   D CB    1 
ATOM   7154  O  OG    . SER   F 3 222 ? 7.513   88.280  -67.675 1.00 62.12  ? 515  SER   D OG    1 
ATOM   7155  N  N     . ALA   F 3 223 ? 10.654  89.236  -69.199 1.00 55.46  ? 516  ALA   D N     1 
ATOM   7156  C  CA    . ALA   F 3 223 ? 11.712  88.432  -69.792 1.00 57.30  ? 516  ALA   D CA    1 
ATOM   7157  C  C     . ALA   F 3 223 ? 11.343  86.950  -69.740 1.00 59.69  ? 516  ALA   D C     1 
ATOM   7158  O  O     . ALA   F 3 223 ? 11.780  86.180  -70.592 1.00 62.69  ? 516  ALA   D O     1 
ATOM   7159  C  CB    . ALA   F 3 223 ? 13.027  88.683  -69.087 1.00 56.59  ? 516  ALA   D CB    1 
ATOM   7160  N  N     . ALA   F 3 224 ? 10.569  86.569  -68.716 1.00 66.23  ? 517  ALA   D N     1 
ATOM   7161  C  CA    . ALA   F 3 224 ? 10.078  85.207  -68.565 1.00 71.33  ? 517  ALA   D CA    1 
ATOM   7162  C  C     . ALA   F 3 224 ? 9.227   84.838  -69.776 1.00 68.20  ? 517  ALA   D C     1 
ATOM   7163  O  O     . ALA   F 3 224 ? 9.521   83.855  -70.452 1.00 69.26  ? 517  ALA   D O     1 
ATOM   7164  C  CB    . ALA   F 3 224 ? 9.284   85.074  -67.281 1.00 69.64  ? 517  ALA   D CB    1 
ATOM   7165  N  N     . ALA   F 3 225 ? 8.216   85.679  -70.053 1.00 65.19  ? 518  ALA   D N     1 
ATOM   7166  C  CA    . ALA   F 3 225 ? 7.239   85.456  -71.111 1.00 65.81  ? 518  ALA   D CA    1 
ATOM   7167  C  C     . ALA   F 3 225 ? 7.839   85.578  -72.516 1.00 64.61  ? 518  ALA   D C     1 
ATOM   7168  O  O     . ALA   F 3 225 ? 7.213   85.136  -73.479 1.00 69.37  ? 518  ALA   D O     1 
ATOM   7169  C  CB    . ALA   F 3 225 ? 6.090   86.414  -70.943 1.00 61.67  ? 518  ALA   D CB    1 
ATOM   7170  N  N     . LEU   F 3 226 ? 9.031   86.180  -72.639 1.00 67.60  ? 519  LEU   D N     1 
ATOM   7171  C  CA    . LEU   F 3 226 ? 9.613   86.473  -73.941 1.00 66.65  ? 519  LEU   D CA    1 
ATOM   7172  C  C     . LEU   F 3 226 ? 10.869  85.644  -74.188 1.00 68.53  ? 519  LEU   D C     1 
ATOM   7173  O  O     . LEU   F 3 226 ? 11.453  85.755  -75.260 1.00 68.97  ? 519  LEU   D O     1 
ATOM   7174  C  CB    . LEU   F 3 226 ? 9.975   87.963  -74.012 1.00 66.28  ? 519  LEU   D CB    1 
ATOM   7175  C  CG    . LEU   F 3 226 ? 8.831   88.968  -73.873 1.00 66.27  ? 519  LEU   D CG    1 
ATOM   7176  C  CD1   . LEU   F 3 226 ? 9.302   90.371  -74.233 1.00 68.70  ? 519  LEU   D CD1   1 
ATOM   7177  C  CD2   . LEU   F 3 226 ? 7.638   88.574  -74.728 1.00 69.40  ? 519  LEU   D CD2   1 
ATOM   7178  N  N     . GLU   F 3 227 ? 11.299  84.846  -73.203 1.00 74.90  ? 520  GLU   D N     1 
ATOM   7179  C  CA    . GLU   F 3 227 ? 12.577  84.151  -73.294 1.00 82.91  ? 520  GLU   D CA    1 
ATOM   7180  C  C     . GLU   F 3 227 ? 12.585  83.172  -74.471 1.00 83.04  ? 520  GLU   D C     1 
ATOM   7181  O  O     . GLU   F 3 227 ? 13.527  83.180  -75.261 1.00 76.96  ? 520  GLU   D O     1 
ATOM   7182  C  CB    . GLU   F 3 227 ? 12.936  83.427  -71.988 1.00 81.65  ? 520  GLU   D CB    1 
ATOM   7183  C  CG    . GLU   F 3 227 ? 14.158  84.007  -71.292 1.00 84.21  ? 520  GLU   D CG    1 
ATOM   7184  C  CD    . GLU   F 3 227 ? 15.443  83.956  -72.107 1.00 82.73  ? 520  GLU   D CD    1 
ATOM   7185  O  OE1   . GLU   F 3 227 ? 16.075  85.016  -72.283 1.00 86.76  ? 520  GLU   D OE1   1 
ATOM   7186  O  OE2   . GLU   F 3 227 ? 15.807  82.856  -72.570 1.00 74.12  ? 520  GLU   D OE2   1 
ATOM   7187  N  N     . ALA   F 3 228 ? 11.541  82.335  -74.581 1.00 86.51  ? 521  ALA   D N     1 
ATOM   7188  C  CA    . ALA   F 3 228 ? 11.480  81.299  -75.605 1.00 88.38  ? 521  ALA   D CA    1 
ATOM   7189  C  C     . ALA   F 3 228 ? 11.403  81.920  -77.000 1.00 80.66  ? 521  ALA   D C     1 
ATOM   7190  O  O     . ALA   F 3 228 ? 11.861  81.316  -77.966 1.00 76.89  ? 521  ALA   D O     1 
ATOM   7191  C  CB    . ALA   F 3 228 ? 10.310  80.367  -75.354 1.00 89.06  ? 521  ALA   D CB    1 
ATOM   7192  N  N     . LEU   F 3 229 ? 10.860  83.143  -77.083 1.00 80.26  ? 522  LEU   D N     1 
ATOM   7193  C  CA    . LEU   F 3 229 ? 10.589  83.813  -78.346 1.00 75.62  ? 522  LEU   D CA    1 
ATOM   7194  C  C     . LEU   F 3 229 ? 11.823  84.537  -78.893 1.00 78.62  ? 522  LEU   D C     1 
ATOM   7195  O  O     . LEU   F 3 229 ? 11.749  85.085  -79.982 1.00 79.63  ? 522  LEU   D O     1 
ATOM   7196  C  CB    . LEU   F 3 229 ? 9.442   84.801  -78.117 1.00 70.82  ? 522  LEU   D CB    1 
ATOM   7197  C  CG    . LEU   F 3 229 ? 8.046   84.195  -78.006 1.00 73.05  ? 522  LEU   D CG    1 
ATOM   7198  C  CD1   . LEU   F 3 229 ? 7.907   83.322  -76.772 1.00 79.12  ? 522  LEU   D CD1   1 
ATOM   7199  C  CD2   . LEU   F 3 229 ? 6.996   85.292  -77.983 1.00 75.36  ? 522  LEU   D CD2   1 
ATOM   7200  N  N     . ARG   F 3 230 ? 12.954  84.523  -78.169 1.00 86.39  ? 523  ARG   D N     1 
ATOM   7201  C  CA    . ARG   F 3 230 ? 14.092  85.387  -78.470 1.00 90.57  ? 523  ARG   D CA    1 
ATOM   7202  C  C     . ARG   F 3 230 ? 14.750  85.026  -79.800 1.00 94.32  ? 523  ARG   D C     1 
ATOM   7203  O  O     . ARG   F 3 230 ? 14.997  85.908  -80.620 1.00 98.95  ? 523  ARG   D O     1 
ATOM   7204  C  CB    . ARG   F 3 230 ? 15.194  85.287  -77.407 1.00 93.70  ? 523  ARG   D CB    1 
ATOM   7205  C  CG    . ARG   F 3 230 ? 14.935  86.052  -76.117 1.00 93.60  ? 523  ARG   D CG    1 
ATOM   7206  C  CD    . ARG   F 3 230 ? 16.067  85.895  -75.108 1.00 89.78  ? 523  ARG   D CD    1 
ATOM   7207  N  NE    . ARG   F 3 230 ? 17.178  86.829  -75.292 1.00 89.06  ? 523  ARG   D NE    1 
ATOM   7208  C  CZ    . ARG   F 3 230 ? 17.586  87.723  -74.387 1.00 89.24  ? 523  ARG   D CZ    1 
ATOM   7209  N  NH1   . ARG   F 3 230 ? 18.242  88.810  -74.766 1.00 77.64  ? 523  ARG   D NH1   1 
ATOM   7210  N  NH2   . ARG   F 3 230 ? 17.305  87.549  -73.107 1.00 86.20  ? 523  ARG   D NH2   1 
ATOM   7211  N  N     . GLU   F 3 231 ? 15.102  83.746  -79.977 1.00 99.79  ? 524  GLU   D N     1 
ATOM   7212  C  CA    . GLU   F 3 231 ? 15.992  83.350  -81.059 1.00 103.16 ? 524  GLU   D CA    1 
ATOM   7213  C  C     . GLU   F 3 231 ? 15.245  83.384  -82.391 1.00 100.77 ? 524  GLU   D C     1 
ATOM   7214  O  O     . GLU   F 3 231 ? 15.833  83.738  -83.410 1.00 96.38  ? 524  GLU   D O     1 
ATOM   7215  C  CB    . GLU   F 3 231 ? 16.605  81.973  -80.787 1.00 105.96 ? 524  GLU   D CB    1 
ATOM   7216  C  CG    . GLU   F 3 231 ? 17.951  81.774  -81.469 1.00 108.54 ? 524  GLU   D CG    1 
ATOM   7217  C  CD    . GLU   F 3 231 ? 18.835  80.690  -80.872 1.00 109.38 ? 524  GLU   D CD    1 
ATOM   7218  O  OE1   . GLU   F 3 231 ? 18.391  80.011  -79.924 1.00 108.68 ? 524  GLU   D OE1   1 
ATOM   7219  O  OE2   . GLU   F 3 231 ? 19.974  80.535  -81.352 1.00 102.37 ? 524  GLU   D OE2   1 
ATOM   7220  N  N     . ALA   F 3 232 ? 13.951  83.031  -82.359 1.00 97.66  ? 525  ALA   D N     1 
ATOM   7221  C  CA    . ALA   F 3 232 ? 13.108  83.020  -83.545 1.00 94.23  ? 525  ALA   D CA    1 
ATOM   7222  C  C     . ALA   F 3 232 ? 12.905  84.439  -84.088 1.00 101.10 ? 525  ALA   D C     1 
ATOM   7223  O  O     . ALA   F 3 232 ? 13.124  84.680  -85.278 1.00 91.03  ? 525  ALA   D O     1 
ATOM   7224  C  CB    . ALA   F 3 232 ? 11.795  82.344  -83.221 1.00 92.28  ? 525  ALA   D CB    1 
ATOM   7225  N  N     . HIS   F 3 233 ? 12.525  85.379  -83.203 1.00 100.07 ? 526  HIS   D N     1 
ATOM   7226  C  CA    . HIS   F 3 233 ? 12.042  86.699  -83.598 1.00 94.05  ? 526  HIS   D CA    1 
ATOM   7227  C  C     . HIS   F 3 233 ? 13.036  87.799  -83.205 1.00 88.01  ? 526  HIS   D C     1 
ATOM   7228  O  O     . HIS   F 3 233 ? 13.129  88.175  -82.039 1.00 82.45  ? 526  HIS   D O     1 
ATOM   7229  C  CB    . HIS   F 3 233 ? 10.653  86.936  -82.983 1.00 87.21  ? 526  HIS   D CB    1 
ATOM   7230  C  CG    . HIS   F 3 233 ? 9.690   85.806  -83.203 1.00 90.22  ? 526  HIS   D CG    1 
ATOM   7231  N  ND1   . HIS   F 3 233 ? 8.716   85.820  -84.166 1.00 87.21  ? 526  HIS   D ND1   1 
ATOM   7232  C  CD2   . HIS   F 3 233 ? 9.598   84.598  -82.573 1.00 90.23  ? 526  HIS   D CD2   1 
ATOM   7233  C  CE1   . HIS   F 3 233 ? 8.036   84.674  -84.124 1.00 91.47  ? 526  HIS   D CE1   1 
ATOM   7234  N  NE2   . HIS   F 3 233 ? 8.570   83.898  -83.143 1.00 89.54  ? 526  HIS   D NE2   1 
ATOM   7235  N  N     . PRO   F 3 234 ? 13.816  88.357  -84.163 1.00 84.48  ? 527  PRO   D N     1 
ATOM   7236  C  CA    . PRO   F 3 234 ? 14.764  89.436  -83.868 1.00 83.80  ? 527  PRO   D CA    1 
ATOM   7237  C  C     . PRO   F 3 234 ? 14.246  90.637  -83.074 1.00 78.49  ? 527  PRO   D C     1 
ATOM   7238  O  O     . PRO   F 3 234 ? 15.023  91.292  -82.385 1.00 77.90  ? 527  PRO   D O     1 
ATOM   7239  C  CB    . PRO   F 3 234 ? 15.188  89.907  -85.271 1.00 85.53  ? 527  PRO   D CB    1 
ATOM   7240  C  CG    . PRO   F 3 234 ? 15.111  88.652  -86.108 1.00 85.85  ? 527  PRO   D CG    1 
ATOM   7241  C  CD    . PRO   F 3 234 ? 13.895  87.923  -85.569 1.00 85.23  ? 527  PRO   D CD    1 
ATOM   7242  N  N     . ILE   F 3 235 ? 12.948  90.943  -83.175 1.00 74.11  ? 528  ILE   D N     1 
ATOM   7243  C  CA    . ILE   F 3 235 ? 12.404  92.129  -82.527 1.00 69.01  ? 528  ILE   D CA    1 
ATOM   7244  C  C     . ILE   F 3 235 ? 12.428  91.954  -81.009 1.00 67.93  ? 528  ILE   D C     1 
ATOM   7245  O  O     . ILE   F 3 235 ? 12.658  92.914  -80.274 1.00 60.69  ? 528  ILE   D O     1 
ATOM   7246  C  CB    . ILE   F 3 235 ? 10.980  92.441  -83.026 1.00 66.12  ? 528  ILE   D CB    1 
ATOM   7247  C  CG1   . ILE   F 3 235 ? 10.588  93.885  -82.688 1.00 66.95  ? 528  ILE   D CG1   1 
ATOM   7248  C  CG2   . ILE   F 3 235 ? 9.979   91.415  -82.504 1.00 68.64  ? 528  ILE   D CG2   1 
ATOM   7249  C  CD1   . ILE   F 3 235 ? 9.100   94.179  -82.721 1.00 65.00  ? 528  ILE   D CD1   1 
ATOM   7250  N  N     . VAL   F 3 236 ? 12.168  90.722  -80.555 1.00 70.45  ? 529  VAL   D N     1 
ATOM   7251  C  CA    . VAL   F 3 236 ? 12.080  90.415  -79.138 1.00 72.60  ? 529  VAL   D CA    1 
ATOM   7252  C  C     . VAL   F 3 236 ? 13.462  90.558  -78.499 1.00 66.92  ? 529  VAL   D C     1 
ATOM   7253  O  O     . VAL   F 3 236 ? 13.586  91.146  -77.430 1.00 63.11  ? 529  VAL   D O     1 
ATOM   7254  C  CB    . VAL   F 3 236 ? 11.455  89.024  -78.922 1.00 76.74  ? 529  VAL   D CB    1 
ATOM   7255  C  CG1   . VAL   F 3 236 ? 11.593  88.545  -77.484 1.00 79.71  ? 529  VAL   D CG1   1 
ATOM   7256  C  CG2   . VAL   F 3 236 ? 9.995   89.011  -79.354 1.00 73.57  ? 529  VAL   D CG2   1 
ATOM   7257  N  N     . GLU   F 3 237 ? 14.499  90.059  -79.178 1.00 66.23  ? 530  GLU   D N     1 
ATOM   7258  C  CA    . GLU   F 3 237 ? 15.874  90.242  -78.731 1.00 69.59  ? 530  GLU   D CA    1 
ATOM   7259  C  C     . GLU   F 3 237 ? 16.208  91.723  -78.554 1.00 63.56  ? 530  GLU   D C     1 
ATOM   7260  O  O     . GLU   F 3 237 ? 16.846  92.107  -77.575 1.00 66.22  ? 530  GLU   D O     1 
ATOM   7261  C  CB    . GLU   F 3 237 ? 16.869  89.618  -79.710 1.00 73.71  ? 530  GLU   D CB    1 
ATOM   7262  C  CG    . GLU   F 3 237 ? 17.512  88.359  -79.169 1.00 89.68  ? 530  GLU   D CG    1 
ATOM   7263  C  CD    . GLU   F 3 237 ? 18.548  88.551  -78.070 1.00 98.28  ? 530  GLU   D CD    1 
ATOM   7264  O  OE1   . GLU   F 3 237 ? 18.926  89.705  -77.741 1.00 99.22  ? 530  GLU   D OE1   1 
ATOM   7265  O  OE2   . GLU   F 3 237 ? 19.020  87.515  -77.572 1.00 105.96 ? 530  GLU   D OE2   1 
ATOM   7266  N  N     . LYS   F 3 238 ? 15.787  92.542  -79.521 1.00 55.71  ? 531  LYS   D N     1 
ATOM   7267  C  CA    . LYS   F 3 238 ? 16.170  93.942  -79.576 1.00 55.53  ? 531  LYS   D CA    1 
ATOM   7268  C  C     . LYS   F 3 238 ? 15.490  94.707  -78.443 1.00 49.45  ? 531  LYS   D C     1 
ATOM   7269  O  O     . LYS   F 3 238 ? 16.077  95.618  -77.874 1.00 48.53  ? 531  LYS   D O     1 
ATOM   7270  C  CB    . LYS   F 3 238 ? 15.790  94.516  -80.946 1.00 59.37  ? 531  LYS   D CB    1 
ATOM   7271  C  CG    . LYS   F 3 238 ? 16.536  93.926  -82.136 1.00 62.10  ? 531  LYS   D CG    1 
ATOM   7272  C  CD    . LYS   F 3 238 ? 17.599  94.846  -82.701 1.00 69.84  ? 531  LYS   D CD    1 
ATOM   7273  C  CE    . LYS   F 3 238 ? 18.350  94.263  -83.882 1.00 69.15  ? 531  LYS   D CE    1 
ATOM   7274  N  NZ    . LYS   F 3 238 ? 19.412  93.334  -83.432 1.00 69.31  ? 531  LYS   D NZ    1 
ATOM   7275  N  N     . ILE   F 3 239 ? 14.240  94.332  -78.138 1.00 47.41  ? 532  ILE   D N     1 
ATOM   7276  C  CA    . ILE   F 3 239 ? 13.467  94.950  -77.073 1.00 50.10  ? 532  ILE   D CA    1 
ATOM   7277  C  C     . ILE   F 3 239 ? 14.102  94.641  -75.714 1.00 50.63  ? 532  ILE   D C     1 
ATOM   7278  O  O     . ILE   F 3 239 ? 14.246  95.535  -74.885 1.00 50.74  ? 532  ILE   D O     1 
ATOM   7279  C  CB    . ILE   F 3 239 ? 11.994  94.500  -77.172 1.00 55.22  ? 532  ILE   D CB    1 
ATOM   7280  C  CG1   . ILE   F 3 239 ? 11.265  95.274  -78.276 1.00 56.74  ? 532  ILE   D CG1   1 
ATOM   7281  C  CG2   . ILE   F 3 239 ? 11.255  94.619  -75.841 1.00 58.02  ? 532  ILE   D CG2   1 
ATOM   7282  C  CD1   . ILE   F 3 239 ? 10.015  94.593  -78.787 1.00 60.82  ? 532  ILE   D CD1   1 
ATOM   7283  N  N     . LEU   F 3 240 ? 14.487  93.383  -75.482 1.00 51.54  ? 533  LEU   D N     1 
ATOM   7284  C  CA    . LEU   F 3 240 ? 15.129  93.004  -74.231 1.00 53.84  ? 533  LEU   D CA    1 
ATOM   7285  C  C     . LEU   F 3 240 ? 16.461  93.737  -74.075 1.00 49.93  ? 533  LEU   D C     1 
ATOM   7286  O  O     . LEU   F 3 240 ? 16.762  94.225  -72.986 1.00 51.82  ? 533  LEU   D O     1 
ATOM   7287  C  CB    . LEU   F 3 240 ? 15.302  91.480  -74.180 1.00 58.94  ? 533  LEU   D CB    1 
ATOM   7288  C  CG    . LEU   F 3 240 ? 13.996  90.680  -74.148 1.00 61.10  ? 533  LEU   D CG    1 
ATOM   7289  C  CD1   . LEU   F 3 240 ? 14.261  89.190  -74.021 1.00 64.07  ? 533  LEU   D CD1   1 
ATOM   7290  C  CD2   . LEU   F 3 240 ? 13.090  91.144  -73.016 1.00 64.96  ? 533  LEU   D CD2   1 
ATOM   7291  N  N     . GLN   F 3 241 ? 17.236  93.876  -75.159 1.00 46.30  ? 534  GLN   D N     1 
ATOM   7292  C  CA    . GLN   F 3 241 ? 18.472  94.648  -75.078 1.00 47.82  ? 534  GLN   D CA    1 
ATOM   7293  C  C     . GLN   F 3 241 ? 18.180  96.121  -74.751 1.00 46.99  ? 534  GLN   D C     1 
ATOM   7294  O  O     . GLN   F 3 241 ? 18.923  96.753  -73.988 1.00 42.02  ? 534  GLN   D O     1 
ATOM   7295  C  CB    . GLN   F 3 241 ? 19.273  94.532  -76.374 1.00 50.59  ? 534  GLN   D CB    1 
ATOM   7296  C  CG    . GLN   F 3 241 ? 19.877  93.163  -76.624 1.00 52.39  ? 534  GLN   D CG    1 
ATOM   7297  C  CD    . GLN   F 3 241 ? 20.457  93.063  -78.016 1.00 56.43  ? 534  GLN   D CD    1 
ATOM   7298  O  OE1   . GLN   F 3 241 ? 20.977  94.029  -78.567 1.00 57.59  ? 534  GLN   D OE1   1 
ATOM   7299  N  NE2   . GLN   F 3 241 ? 20.371  91.881  -78.601 1.00 59.36  ? 534  GLN   D NE2   1 
ATOM   7300  N  N     . TYR   F 3 242 ? 17.110  96.673  -75.352 1.00 45.97  ? 535  TYR   D N     1 
ATOM   7301  C  CA    . TYR   F 3 242 ? 16.704  98.062  -75.131 1.00 47.74  ? 535  TYR   D CA    1 
ATOM   7302  C  C     . TYR   F 3 242 ? 16.384  98.270  -73.652 1.00 42.05  ? 535  TYR   D C     1 
ATOM   7303  O  O     . TYR   F 3 242 ? 16.790  99.261  -73.035 1.00 43.59  ? 535  TYR   D O     1 
ATOM   7304  C  CB    . TYR   F 3 242 ? 15.482  98.428  -75.993 1.00 46.60  ? 535  TYR   D CB    1 
ATOM   7305  C  CG    . TYR   F 3 242 ? 14.911  99.804  -75.754 1.00 44.30  ? 535  TYR   D CG    1 
ATOM   7306  C  CD1   . TYR   F 3 242 ? 15.395  100.919 -76.422 1.00 44.93  ? 535  TYR   D CD1   1 
ATOM   7307  C  CD2   . TYR   F 3 242 ? 13.886  99.997  -74.841 1.00 45.44  ? 535  TYR   D CD2   1 
ATOM   7308  C  CE1   . TYR   F 3 242 ? 14.869  102.185 -76.196 1.00 43.89  ? 535  TYR   D CE1   1 
ATOM   7309  C  CE2   . TYR   F 3 242 ? 13.378  101.261 -74.575 1.00 43.44  ? 535  TYR   D CE2   1 
ATOM   7310  C  CZ    . TYR   F 3 242 ? 13.858  102.356 -75.267 1.00 44.70  ? 535  TYR   D CZ    1 
ATOM   7311  O  OH    . TYR   F 3 242 ? 13.310  103.595 -75.022 1.00 51.16  ? 535  TYR   D OH    1 
ATOM   7312  N  N     . ARG   F 3 243 ? 15.618  97.323  -73.107 1.00 43.17  ? 536  ARG   D N     1 
ATOM   7313  C  CA    . ARG   F 3 243 ? 15.210  97.364  -71.711 1.00 44.89  ? 536  ARG   D CA    1 
ATOM   7314  C  C     . ARG   F 3 243 ? 16.426  97.395  -70.793 1.00 41.12  ? 536  ARG   D C     1 
ATOM   7315  O  O     . ARG   F 3 243 ? 16.491  98.242  -69.904 1.00 41.06  ? 536  ARG   D O     1 
ATOM   7316  C  CB    . ARG   F 3 243 ? 14.308  96.178  -71.388 1.00 42.92  ? 536  ARG   D CB    1 
ATOM   7317  C  CG    . ARG   F 3 243 ? 12.848  96.447  -71.708 1.00 44.29  ? 536  ARG   D CG    1 
ATOM   7318  C  CD    . ARG   F 3 243 ? 12.035  95.459  -70.921 1.00 47.30  ? 536  ARG   D CD    1 
ATOM   7319  N  NE    . ARG   F 3 243 ? 10.615  95.589  -71.148 1.00 47.28  ? 536  ARG   D NE    1 
ATOM   7320  C  CZ    . ARG   F 3 243 ? 9.790   94.564  -71.268 1.00 47.44  ? 536  ARG   D CZ    1 
ATOM   7321  N  NH1   . ARG   F 3 243 ? 10.250  93.325  -71.194 1.00 50.15  ? 536  ARG   D NH1   1 
ATOM   7322  N  NH2   . ARG   F 3 243 ? 8.499   94.790  -71.421 1.00 50.81  ? 536  ARG   D NH2   1 
ATOM   7323  N  N     . GLU   F 3 244 ? 17.404  96.523  -71.054 1.00 37.88  ? 537  GLU   D N     1 
ATOM   7324  C  CA    . GLU   F 3 244 ? 18.581  96.459  -70.205 1.00 41.40  ? 537  GLU   D CA    1 
ATOM   7325  C  C     . GLU   F 3 244 ? 19.327  97.797  -70.227 1.00 40.76  ? 537  GLU   D C     1 
ATOM   7326  O  O     . GLU   F 3 244 ? 19.654  98.352  -69.173 1.00 42.22  ? 537  GLU   D O     1 
ATOM   7327  C  CB    . GLU   F 3 244 ? 19.501  95.307  -70.619 1.00 41.02  ? 537  GLU   D CB    1 
ATOM   7328  C  CG    . GLU   F 3 244 ? 20.724  95.242  -69.734 1.00 45.88  ? 537  GLU   D CG    1 
ATOM   7329  C  CD    . GLU   F 3 244 ? 21.851  94.345  -70.194 1.00 47.45  ? 537  GLU   D CD    1 
ATOM   7330  O  OE1   . GLU   F 3 244 ? 21.622  93.515  -71.079 1.00 63.13  ? 537  GLU   D OE1   1 
ATOM   7331  O  OE2   . GLU   F 3 244 ? 22.956  94.488  -69.654 1.00 60.52  ? 537  GLU   D OE2   1 
ATOM   7332  N  N     . LEU   F 3 245 ? 19.615  98.303  -71.433 1.00 42.67  ? 538  LEU   D N     1 
ATOM   7333  C  CA    . LEU   F 3 245 ? 20.374  99.540  -71.586 1.00 40.36  ? 538  LEU   D CA    1 
ATOM   7334  C  C     . LEU   F 3 245 ? 19.644  100.702 -70.927 1.00 34.69  ? 538  LEU   D C     1 
ATOM   7335  O  O     . LEU   F 3 245 ? 20.282  101.502 -70.260 1.00 39.20  ? 538  LEU   D O     1 
ATOM   7336  C  CB    . LEU   F 3 245 ? 20.616  99.825  -73.073 1.00 44.91  ? 538  LEU   D CB    1 
ATOM   7337  C  CG    . LEU   F 3 245 ? 21.578  98.877  -73.792 1.00 50.32  ? 538  LEU   D CG    1 
ATOM   7338  C  CD1   . LEU   F 3 245 ? 21.367  98.925  -75.293 1.00 53.54  ? 538  LEU   D CD1   1 
ATOM   7339  C  CD2   . LEU   F 3 245 ? 23.021  99.200  -73.479 1.00 54.33  ? 538  LEU   D CD2   1 
ATOM   7340  N  N     . THR   F 3 246 ? 18.323  100.807 -71.114 1.00 36.37  ? 539  THR   D N     1 
ATOM   7341  C  CA    . THR   F 3 246 ? 17.555  101.923 -70.559 1.00 43.48  ? 539  THR   D CA    1 
ATOM   7342  C  C     . THR   F 3 246 ? 17.468  101.831 -69.034 1.00 41.75  ? 539  THR   D C     1 
ATOM   7343  O  O     . THR   F 3 246 ? 17.476  102.851 -68.336 1.00 43.31  ? 539  THR   D O     1 
ATOM   7344  C  CB    . THR   F 3 246 ? 16.147  102.009 -71.174 1.00 46.38  ? 539  THR   D CB    1 
ATOM   7345  O  OG1   . THR   F 3 246 ? 15.627  100.690 -71.346 1.00 47.94  ? 539  THR   D OG1   1 
ATOM   7346  C  CG2   . THR   F 3 246 ? 16.131  102.675 -72.531 1.00 47.49  ? 539  THR   D CG2   1 
ATOM   7347  N  N     . LYS   F 3 247 ? 17.368  100.600 -68.528 1.00 42.86  ? 540  LYS   D N     1 
ATOM   7348  C  CA    . LYS   F 3 247 ? 17.342  100.324 -67.097 1.00 42.11  ? 540  LYS   D CA    1 
ATOM   7349  C  C     . LYS   F 3 247 ? 18.655  100.792 -66.485 1.00 39.76  ? 540  LYS   D C     1 
ATOM   7350  O  O     . LYS   F 3 247 ? 18.669  101.577 -65.528 1.00 39.34  ? 540  LYS   D O     1 
ATOM   7351  C  CB    . LYS   F 3 247 ? 17.158  98.819  -66.880 1.00 45.56  ? 540  LYS   D CB    1 
ATOM   7352  C  CG    . LYS   F 3 247 ? 17.240  98.305  -65.446 1.00 45.94  ? 540  LYS   D CG    1 
ATOM   7353  C  CD    . LYS   F 3 247 ? 15.964  98.510  -64.709 1.00 45.27  ? 540  LYS   D CD    1 
ATOM   7354  C  CE    . LYS   F 3 247 ? 15.820  97.640  -63.485 1.00 42.20  ? 540  LYS   D CE    1 
ATOM   7355  N  NZ    . LYS   F 3 247 ? 14.495  97.895  -62.869 1.00 44.56  ? 540  LYS   D NZ    1 
ATOM   7356  N  N     . LEU   F 3 248 ? 19.762  100.297 -67.052 1.00 38.79  ? 541  LEU   D N     1 
ATOM   7357  C  CA    . LEU   F 3 248 ? 21.071  100.563 -66.475 1.00 37.45  ? 541  LEU   D CA    1 
ATOM   7358  C  C     . LEU   F 3 248 ? 21.393  102.050 -66.584 1.00 37.10  ? 541  LEU   D C     1 
ATOM   7359  O  O     . LEU   F 3 248 ? 21.934  102.632 -65.642 1.00 39.38  ? 541  LEU   D O     1 
ATOM   7360  C  CB    . LEU   F 3 248 ? 22.131  99.673  -67.129 1.00 38.85  ? 541  LEU   D CB    1 
ATOM   7361  C  CG    . LEU   F 3 248 ? 21.953  98.156  -66.949 1.00 44.38  ? 541  LEU   D CG    1 
ATOM   7362  C  CD1   . LEU   F 3 248 ? 23.294  97.434  -66.930 1.00 43.62  ? 541  LEU   D CD1   1 
ATOM   7363  C  CD2   . LEU   F 3 248 ? 21.146  97.787  -65.707 1.00 43.49  ? 541  LEU   D CD2   1 
ATOM   7364  N  N     . LYS   F 3 249 ? 20.976  102.690 -67.684 1.00 38.05  ? 542  LYS   D N     1 
ATOM   7365  C  CA    . LYS   F 3 249 ? 21.283  104.102 -67.887 1.00 38.95  ? 542  LYS   D CA    1 
ATOM   7366  C  C     . LYS   F 3 249 ? 20.536  104.985 -66.887 1.00 35.47  ? 542  LYS   D C     1 
ATOM   7367  O  O     . LYS   F 3 249 ? 21.131  105.851 -66.244 1.00 40.40  ? 542  LYS   D O     1 
ATOM   7368  C  CB    . LYS   F 3 249 ? 20.952  104.499 -69.330 1.00 41.49  ? 542  LYS   D CB    1 
ATOM   7369  C  CG    . LYS   F 3 249 ? 21.169  105.967 -69.677 1.00 41.12  ? 542  LYS   D CG    1 
ATOM   7370  C  CD    . LYS   F 3 249 ? 21.337  106.201 -71.181 1.00 46.21  ? 542  LYS   D CD    1 
ATOM   7371  C  CE    . LYS   F 3 249 ? 20.869  107.565 -71.646 1.00 45.41  ? 542  LYS   D CE    1 
ATOM   7372  N  NZ    . LYS   F 3 249 ? 21.444  108.669 -70.840 1.00 46.78  ? 542  LYS   D NZ    1 
ATOM   7373  N  N     . SER   F 3 250 ? 19.216  104.785 -66.792 1.00 38.08  ? 543  SER   D N     1 
ATOM   7374  C  CA    . SER   F 3 250 ? 18.344  105.586 -65.941 1.00 38.77  ? 543  SER   D CA    1 
ATOM   7375  C  C     . SER   F 3 250 ? 18.555  105.309 -64.450 1.00 36.68  ? 543  SER   D C     1 
ATOM   7376  O  O     . SER   F 3 250 ? 18.328  106.188 -63.624 1.00 39.12  ? 543  SER   D O     1 
ATOM   7377  C  CB    . SER   F 3 250 ? 16.906  105.340 -66.301 1.00 42.44  ? 543  SER   D CB    1 
ATOM   7378  O  OG    . SER   F 3 250 ? 16.537  103.999 -65.993 1.00 47.37  ? 543  SER   D OG    1 
ATOM   7379  N  N     . THR   F 3 251 ? 18.929  104.076 -64.082 1.00 35.65  ? 544  THR   D N     1 
ATOM   7380  C  CA    . THR   F 3 251 ? 19.010  103.723 -62.672 1.00 33.44  ? 544  THR   D CA    1 
ATOM   7381  C  C     . THR   F 3 251 ? 20.423  103.874 -62.105 1.00 34.24  ? 544  THR   D C     1 
ATOM   7382  O  O     . THR   F 3 251 ? 20.551  104.268 -60.948 1.00 33.18  ? 544  THR   D O     1 
ATOM   7383  C  CB    . THR   F 3 251 ? 18.499  102.313 -62.402 1.00 34.63  ? 544  THR   D CB    1 
ATOM   7384  O  OG1   . THR   F 3 251 ? 17.251  102.173 -63.081 1.00 31.70  ? 544  THR   D OG1   1 
ATOM   7385  C  CG2   . THR   F 3 251 ? 18.367  102.065 -60.912 1.00 35.36  ? 544  THR   D CG2   1 
ATOM   7386  N  N     . TYR   F 3 252 ? 21.467  103.630 -62.915 1.00 32.81  ? 545  TYR   D N     1 
ATOM   7387  C  CA    . TYR   F 3 252 ? 22.827  103.576 -62.395 1.00 35.13  ? 545  TYR   D CA    1 
ATOM   7388  C  C     . TYR   F 3 252 ? 23.767  104.564 -63.085 1.00 36.38  ? 545  TYR   D C     1 
ATOM   7389  O  O     . TYR   F 3 252 ? 24.421  105.361 -62.415 1.00 33.59  ? 545  TYR   D O     1 
ATOM   7390  C  CB    . TYR   F 3 252 ? 23.375  102.151 -62.558 1.00 37.07  ? 545  TYR   D CB    1 
ATOM   7391  C  CG    . TYR   F 3 252 ? 22.534  101.119 -61.861 1.00 35.21  ? 545  TYR   D CG    1 
ATOM   7392  C  CD1   . TYR   F 3 252 ? 22.551  100.999 -60.474 1.00 33.61  ? 545  TYR   D CD1   1 
ATOM   7393  C  CD2   . TYR   F 3 252 ? 21.635  100.344 -62.574 1.00 35.82  ? 545  TYR   D CD2   1 
ATOM   7394  C  CE1   . TYR   F 3 252 ? 21.741  100.081 -59.824 1.00 33.90  ? 545  TYR   D CE1   1 
ATOM   7395  C  CE2   . TYR   F 3 252 ? 20.805  99.433  -61.933 1.00 37.83  ? 545  TYR   D CE2   1 
ATOM   7396  C  CZ    . TYR   F 3 252 ? 20.865  99.300  -60.556 1.00 33.73  ? 545  TYR   D CZ    1 
ATOM   7397  O  OH    . TYR   F 3 252 ? 20.081  98.375  -59.944 1.00 35.56  ? 545  TYR   D OH    1 
ATOM   7398  N  N     . ILE   F 3 253 ? 23.887  104.465 -64.417 1.00 42.10  ? 546  ILE   D N     1 
ATOM   7399  C  CA    . ILE   F 3 253 ? 24.961  105.128 -65.155 1.00 42.68  ? 546  ILE   D CA    1 
ATOM   7400  C  C     . ILE   F 3 253 ? 24.849  106.652 -65.034 1.00 39.76  ? 546  ILE   D C     1 
ATOM   7401  O  O     . ILE   F 3 253 ? 25.839  107.310 -64.730 1.00 39.37  ? 546  ILE   D O     1 
ATOM   7402  C  CB    . ILE   F 3 253 ? 24.996  104.676 -66.629 1.00 43.49  ? 546  ILE   D CB    1 
ATOM   7403  C  CG1   . ILE   F 3 253 ? 25.294  103.179 -66.761 1.00 41.53  ? 546  ILE   D CG1   1 
ATOM   7404  C  CG2   . ILE   F 3 253 ? 25.996  105.512 -67.407 1.00 44.25  ? 546  ILE   D CG2   1 
ATOM   7405  C  CD1   . ILE   F 3 253 ? 25.059  102.620 -68.141 1.00 41.34  ? 546  ILE   D CD1   1 
ATOM   7406  N  N     . ASP   F 3 254 ? 23.649  107.211 -65.236 1.00 39.23  ? 547  ASP   D N     1 
ATOM   7407  C  CA    . ASP   F 3 254 ? 23.478  108.664 -65.195 1.00 39.71  ? 547  ASP   D CA    1 
ATOM   7408  C  C     . ASP   F 3 254 ? 23.353  109.189 -63.762 1.00 37.75  ? 547  ASP   D C     1 
ATOM   7409  O  O     . ASP   F 3 254 ? 24.016  110.161 -63.417 1.00 44.49  ? 547  ASP   D O     1 
ATOM   7410  C  CB    . ASP   F 3 254 ? 22.273  109.124 -66.033 1.00 39.76  ? 547  ASP   D CB    1 
ATOM   7411  C  CG    . ASP   F 3 254 ? 22.422  108.896 -67.529 1.00 41.21  ? 547  ASP   D CG    1 
ATOM   7412  O  OD1   . ASP   F 3 254 ? 23.582  108.833 -68.023 1.00 40.41  ? 547  ASP   D OD1   1 
ATOM   7413  O  OD2   . ASP   F 3 254 ? 21.377  108.748 -68.187 1.00 43.49  ? 547  ASP   D OD2   1 
ATOM   7414  N  N     . PRO   F 3 255 ? 22.452  108.658 -62.901 1.00 37.42  ? 548  PRO   D N     1 
ATOM   7415  C  CA    . PRO   F 3 255 ? 22.257  109.203 -61.551 1.00 38.32  ? 548  PRO   D CA    1 
ATOM   7416  C  C     . PRO   F 3 255 ? 23.414  109.116 -60.560 1.00 38.84  ? 548  PRO   D C     1 
ATOM   7417  O  O     . PRO   F 3 255 ? 23.561  109.997 -59.718 1.00 43.48  ? 548  PRO   D O     1 
ATOM   7418  C  CB    . PRO   F 3 255 ? 21.137  108.348 -60.932 1.00 37.38  ? 548  PRO   D CB    1 
ATOM   7419  C  CG    . PRO   F 3 255 ? 20.464  107.680 -62.117 1.00 39.10  ? 548  PRO   D CG    1 
ATOM   7420  C  CD    . PRO   F 3 255 ? 21.524  107.554 -63.194 1.00 38.63  ? 548  PRO   D CD    1 
ATOM   7421  N  N     . LEU   F 3 256 ? 24.187  108.023 -60.609 1.00 36.61  ? 549  LEU   D N     1 
ATOM   7422  C  CA    . LEU   F 3 256 ? 25.177  107.768 -59.570 1.00 38.59  ? 549  LEU   D CA    1 
ATOM   7423  C  C     . LEU   F 3 256 ? 26.276  108.829 -59.604 1.00 37.99  ? 549  LEU   D C     1 
ATOM   7424  O  O     . LEU   F 3 256 ? 26.659  109.336 -58.553 1.00 38.55  ? 549  LEU   D O     1 
ATOM   7425  C  CB    . LEU   F 3 256 ? 25.770  106.358 -59.728 1.00 39.53  ? 549  LEU   D CB    1 
ATOM   7426  C  CG    . LEU   F 3 256 ? 24.862  105.195 -59.323 1.00 40.32  ? 549  LEU   D CG    1 
ATOM   7427  C  CD1   . LEU   F 3 256 ? 25.533  103.874 -59.633 1.00 40.21  ? 549  LEU   D CD1   1 
ATOM   7428  C  CD2   . LEU   F 3 256 ? 24.477  105.263 -57.850 1.00 41.82  ? 549  LEU   D CD2   1 
ATOM   7429  N  N     . PRO   F 3 257 ? 26.863  109.174 -60.778 1.00 38.76  ? 550  PRO   D N     1 
ATOM   7430  C  CA    . PRO   F 3 257 ? 27.955  110.148 -60.810 1.00 40.14  ? 550  PRO   D CA    1 
ATOM   7431  C  C     . PRO   F 3 257 ? 27.521  111.548 -60.358 1.00 44.25  ? 550  PRO   D C     1 
ATOM   7432  O  O     . PRO   F 3 257 ? 28.353  112.336 -59.915 1.00 47.37  ? 550  PRO   D O     1 
ATOM   7433  C  CB    . PRO   F 3 257 ? 28.459  110.109 -62.259 1.00 41.60  ? 550  PRO   D CB    1 
ATOM   7434  C  CG    . PRO   F 3 257 ? 27.333  109.488 -63.071 1.00 41.43  ? 550  PRO   D CG    1 
ATOM   7435  C  CD    . PRO   F 3 257 ? 26.574  108.604 -62.107 1.00 39.77  ? 550  PRO   D CD    1 
ATOM   7436  N  N     . ASP   F 3 258 ? 26.207  111.816 -60.393 1.00 42.68  ? 551  ASP   D N     1 
ATOM   7437  C  CA    . ASP   F 3 258 ? 25.651  113.093 -59.977 1.00 47.72  ? 551  ASP   D CA    1 
ATOM   7438  C  C     . ASP   F 3 258 ? 25.437  113.147 -58.459 1.00 48.16  ? 551  ASP   D C     1 
ATOM   7439  O  O     . ASP   F 3 258 ? 25.036  114.192 -57.940 1.00 44.37  ? 551  ASP   D O     1 
ATOM   7440  C  CB    . ASP   F 3 258 ? 24.339  113.364 -60.732 1.00 47.00  ? 551  ASP   D CB    1 
ATOM   7441  C  CG    . ASP   F 3 258 ? 24.510  113.709 -62.211 1.00 46.86  ? 551  ASP   D CG    1 
ATOM   7442  O  OD1   . ASP   F 3 258 ? 25.678  114.009 -62.658 1.00 44.91  ? 551  ASP   D OD1   1 
ATOM   7443  O  OD2   . ASP   F 3 258 ? 23.480  113.675 -62.919 1.00 40.73  ? 551  ASP   D OD2   1 
ATOM   7444  N  N     . LEU   F 3 259 ? 25.691  112.032 -57.758 1.00 46.54  ? 552  LEU   D N     1 
ATOM   7445  C  CA    . LEU   F 3 259 ? 25.443  111.921 -56.322 1.00 45.98  ? 552  LEU   D CA    1 
ATOM   7446  C  C     . LEU   F 3 259 ? 26.749  112.014 -55.532 1.00 38.52  ? 552  LEU   D C     1 
ATOM   7447  O  O     . LEU   F 3 259 ? 26.758  111.818 -54.318 1.00 41.28  ? 552  LEU   D O     1 
ATOM   7448  C  CB    . LEU   F 3 259 ? 24.725  110.591 -56.029 1.00 46.72  ? 552  LEU   D CB    1 
ATOM   7449  C  CG    . LEU   F 3 259 ? 23.216  110.566 -56.305 1.00 47.68  ? 552  LEU   D CG    1 
ATOM   7450  C  CD1   . LEU   F 3 259 ? 22.642  109.160 -56.110 1.00 43.38  ? 552  LEU   D CD1   1 
ATOM   7451  C  CD2   . LEU   F 3 259 ? 22.478  111.575 -55.425 1.00 43.10  ? 552  LEU   D CD2   1 
ATOM   7452  N  N     . ILE   F 3 260 ? 27.857  112.290 -56.225 1.00 38.61  ? 553  ILE   D N     1 
ATOM   7453  C  CA    . ILE   F 3 260 ? 29.130  112.521 -55.563 1.00 40.11  ? 553  ILE   D CA    1 
ATOM   7454  C  C     . ILE   F 3 260 ? 28.949  113.690 -54.597 1.00 41.69  ? 553  ILE   D C     1 
ATOM   7455  O  O     . ILE   F 3 260 ? 28.305  114.683 -54.930 1.00 48.08  ? 553  ILE   D O     1 
ATOM   7456  C  CB    . ILE   F 3 260 ? 30.260  112.770 -56.584 1.00 44.21  ? 553  ILE   D CB    1 
ATOM   7457  C  CG1   . ILE   F 3 260 ? 30.503  111.558 -57.487 1.00 47.13  ? 553  ILE   D CG1   1 
ATOM   7458  C  CG2   . ILE   F 3 260 ? 31.549  113.216 -55.902 1.00 47.43  ? 553  ILE   D CG2   1 
ATOM   7459  C  CD1   . ILE   F 3 260 ? 30.760  110.277 -56.743 1.00 48.03  ? 553  ILE   D CD1   1 
ATOM   7460  N  N     . HIS   F 3 261 ? 29.527  113.560 -53.399 1.00 37.17  ? 554  HIS   D N     1 
ATOM   7461  C  CA    . HIS   F 3 261 ? 29.187  114.439 -52.304 1.00 36.79  ? 554  HIS   D CA    1 
ATOM   7462  C  C     . HIS   F 3 261 ? 30.309  115.455 -52.103 1.00 41.05  ? 554  HIS   D C     1 
ATOM   7463  O  O     . HIS   F 3 261 ? 31.489  115.088 -52.098 1.00 38.85  ? 554  HIS   D O     1 
ATOM   7464  C  CB    . HIS   F 3 261 ? 28.915  113.620 -51.035 1.00 33.97  ? 554  HIS   D CB    1 
ATOM   7465  C  CG    . HIS   F 3 261 ? 28.361  114.414 -49.894 1.00 34.98  ? 554  HIS   D CG    1 
ATOM   7466  N  ND1   . HIS   F 3 261 ? 29.094  115.321 -49.169 1.00 41.15  ? 554  HIS   D ND1   1 
ATOM   7467  C  CD2   . HIS   F 3 261 ? 27.109  114.425 -49.370 1.00 38.31  ? 554  HIS   D CD2   1 
ATOM   7468  C  CE1   . HIS   F 3 261 ? 28.332  115.848 -48.210 1.00 38.42  ? 554  HIS   D CE1   1 
ATOM   7469  N  NE2   . HIS   F 3 261 ? 27.098  115.309 -48.317 1.00 36.90  ? 554  HIS   D NE2   1 
ATOM   7470  N  N     . PRO   F 3 262 ? 29.960  116.759 -51.967 1.00 44.20  ? 555  PRO   D N     1 
ATOM   7471  C  CA    . PRO   F 3 262 ? 30.949  117.831 -51.816 1.00 44.72  ? 555  PRO   D CA    1 
ATOM   7472  C  C     . PRO   F 3 262 ? 31.944  117.699 -50.664 1.00 46.82  ? 555  PRO   D C     1 
ATOM   7473  O  O     . PRO   F 3 262 ? 33.082  118.140 -50.779 1.00 47.34  ? 555  PRO   D O     1 
ATOM   7474  C  CB    . PRO   F 3 262 ? 30.106  119.096 -51.586 1.00 45.60  ? 555  PRO   D CB    1 
ATOM   7475  C  CG    . PRO   F 3 262 ? 28.706  118.604 -51.293 1.00 42.86  ? 555  PRO   D CG    1 
ATOM   7476  C  CD    . PRO   F 3 262 ? 28.581  117.277 -52.012 1.00 42.94  ? 555  PRO   D CD    1 
ATOM   7477  N  N     . ARG   F 3 263 ? 31.539  117.080 -49.555 1.00 48.38  ? 556  ARG   D N     1 
ATOM   7478  C  CA    . ARG   F 3 263 ? 32.403  117.060 -48.391 1.00 47.30  ? 556  ARG   D CA    1 
ATOM   7479  C  C     . ARG   F 3 263 ? 33.406  115.907 -48.440 1.00 44.06  ? 556  ARG   D C     1 
ATOM   7480  O  O     . ARG   F 3 263 ? 34.391  115.929 -47.702 1.00 39.94  ? 556  ARG   D O     1 
ATOM   7481  C  CB    . ARG   F 3 263 ? 31.565  116.978 -47.116 1.00 58.84  ? 556  ARG   D CB    1 
ATOM   7482  C  CG    . ARG   F 3 263 ? 32.028  117.971 -46.053 1.00 64.97  ? 556  ARG   D CG    1 
ATOM   7483  C  CD    . ARG   F 3 263 ? 31.348  119.324 -46.165 1.00 56.95  ? 556  ARG   D CD    1 
ATOM   7484  N  NE    . ARG   F 3 263 ? 30.637  119.503 -44.914 1.00 64.14  ? 556  ARG   D NE    1 
ATOM   7485  C  CZ    . ARG   F 3 263 ? 29.334  119.308 -44.736 1.00 70.40  ? 556  ARG   D CZ    1 
ATOM   7486  N  NH1   . ARG   F 3 263 ? 28.482  119.416 -45.745 1.00 71.01  ? 556  ARG   D NH1   1 
ATOM   7487  N  NH2   . ARG   F 3 263 ? 28.878  119.083 -43.514 1.00 73.22  ? 556  ARG   D NH2   1 
ATOM   7488  N  N     . THR   F 3 264 ? 33.152  114.894 -49.280 1.00 38.74  ? 557  THR   D N     1 
ATOM   7489  C  CA    . THR   F 3 264 ? 33.977  113.691 -49.282 1.00 39.18  ? 557  THR   D CA    1 
ATOM   7490  C  C     . THR   F 3 264 ? 34.550  113.381 -50.663 1.00 38.08  ? 557  THR   D C     1 
ATOM   7491  O  O     . THR   F 3 264 ? 35.567  112.701 -50.762 1.00 42.40  ? 557  THR   D O     1 
ATOM   7492  C  CB    . THR   F 3 264 ? 33.166  112.476 -48.816 1.00 40.42  ? 557  THR   D CB    1 
ATOM   7493  O  OG1   . THR   F 3 264 ? 32.135  112.236 -49.784 1.00 37.04  ? 557  THR   D OG1   1 
ATOM   7494  C  CG2   . THR   F 3 264 ? 32.576  112.683 -47.434 1.00 37.38  ? 557  THR   D CG2   1 
ATOM   7495  N  N     . GLY   F 3 265 ? 33.851  113.823 -51.716 1.00 38.24  ? 558  GLY   D N     1 
ATOM   7496  C  CA    . GLY   F 3 265 ? 34.154  113.427 -53.080 1.00 40.50  ? 558  GLY   D CA    1 
ATOM   7497  C  C     . GLY   F 3 265 ? 33.764  111.980 -53.370 1.00 39.15  ? 558  GLY   D C     1 
ATOM   7498  O  O     . GLY   F 3 265 ? 34.310  111.371 -54.282 1.00 39.65  ? 558  GLY   D O     1 
ATOM   7499  N  N     . ARG   F 3 266 ? 32.788  111.458 -52.608 1.00 42.50  ? 559  ARG   D N     1 
ATOM   7500  C  CA    . ARG   F 3 266 ? 32.396  110.056 -52.698 1.00 41.91  ? 559  ARG   D CA    1 
ATOM   7501  C  C     . ARG   F 3 266 ? 30.871  109.922 -52.766 1.00 41.59  ? 559  ARG   D C     1 
ATOM   7502  O  O     . ARG   F 3 266 ? 30.116  110.880 -52.543 1.00 34.66  ? 559  ARG   D O     1 
ATOM   7503  C  CB    . ARG   F 3 266 ? 33.027  109.287 -51.530 1.00 41.76  ? 559  ARG   D CB    1 
ATOM   7504  C  CG    . ARG   F 3 266 ? 34.543  109.160 -51.656 1.00 39.87  ? 559  ARG   D CG    1 
ATOM   7505  C  CD    . ARG   F 3 266 ? 35.319  108.807 -50.402 1.00 41.17  ? 559  ARG   D CD    1 
ATOM   7506  N  NE    . ARG   F 3 266 ? 35.164  107.417 -49.995 1.00 42.84  ? 559  ARG   D NE    1 
ATOM   7507  C  CZ    . ARG   F 3 266 ? 36.074  106.453 -50.102 1.00 40.87  ? 559  ARG   D CZ    1 
ATOM   7508  N  NH1   . ARG   F 3 266 ? 37.187  106.633 -50.788 1.00 38.28  ? 559  ARG   D NH1   1 
ATOM   7509  N  NH2   . ARG   F 3 266 ? 35.836  105.278 -49.541 1.00 42.72  ? 559  ARG   D NH2   1 
ATOM   7510  N  N     . LEU   F 3 267 ? 30.457  108.696 -53.106 1.00 37.14  ? 560  LEU   D N     1 
ATOM   7511  C  CA    . LEU   F 3 267 ? 29.065  108.290 -53.187 1.00 34.50  ? 560  LEU   D CA    1 
ATOM   7512  C  C     . LEU   F 3 267 ? 28.652  107.622 -51.871 1.00 33.82  ? 560  LEU   D C     1 
ATOM   7513  O  O     . LEU   F 3 267 ? 29.315  106.684 -51.403 1.00 32.46  ? 560  LEU   D O     1 
ATOM   7514  C  CB    . LEU   F 3 267 ? 28.956  107.324 -54.373 1.00 36.74  ? 560  LEU   D CB    1 
ATOM   7515  C  CG    . LEU   F 3 267 ? 27.584  106.697 -54.601 1.00 36.35  ? 560  LEU   D CG    1 
ATOM   7516  C  CD1   . LEU   F 3 267 ? 26.571  107.777 -54.875 1.00 39.14  ? 560  LEU   D CD1   1 
ATOM   7517  C  CD2   . LEU   F 3 267 ? 27.605  105.715 -55.750 1.00 36.75  ? 560  LEU   D CD2   1 
ATOM   7518  N  N     . HIS   F 3 268 ? 27.538  108.099 -51.295 1.00 33.65  ? 561  HIS   D N     1 
ATOM   7519  C  CA    . HIS   F 3 268 ? 27.047  107.640 -50.005 1.00 34.06  ? 561  HIS   D CA    1 
ATOM   7520  C  C     . HIS   F 3 268 ? 25.667  106.997 -50.140 1.00 39.07  ? 561  HIS   D C     1 
ATOM   7521  O  O     . HIS   F 3 268 ? 24.831  107.460 -50.913 1.00 49.44  ? 561  HIS   D O     1 
ATOM   7522  C  CB    . HIS   F 3 268 ? 27.027  108.776 -48.986 1.00 34.06  ? 561  HIS   D CB    1 
ATOM   7523  C  CG    . HIS   F 3 268 ? 28.374  109.380 -48.743 1.00 34.63  ? 561  HIS   D CG    1 
ATOM   7524  N  ND1   . HIS   F 3 268 ? 29.149  109.088 -47.669 1.00 36.30  ? 561  HIS   D ND1   1 
ATOM   7525  C  CD2   . HIS   F 3 268 ? 29.091  110.245 -49.511 1.00 37.84  ? 561  HIS   D CD2   1 
ATOM   7526  C  CE1   . HIS   F 3 268 ? 30.303  109.753 -47.756 1.00 38.30  ? 561  HIS   D CE1   1 
ATOM   7527  N  NE2   . HIS   F 3 268 ? 30.282  110.485 -48.883 1.00 38.13  ? 561  HIS   D NE2   1 
ATOM   7528  N  N     . THR   F 3 269 ? 25.472  105.895 -49.396 1.00 37.23  ? 562  THR   D N     1 
ATOM   7529  C  CA    . THR   F 3 269 ? 24.231  105.141 -49.375 1.00 35.95  ? 562  THR   D CA    1 
ATOM   7530  C  C     . THR   F 3 269 ? 23.756  105.110 -47.931 1.00 33.59  ? 562  THR   D C     1 
ATOM   7531  O  O     . THR   F 3 269 ? 24.473  105.558 -47.041 1.00 34.05  ? 562  THR   D O     1 
ATOM   7532  C  CB    . THR   F 3 269 ? 24.390  103.711 -49.925 1.00 36.04  ? 562  THR   D CB    1 
ATOM   7533  O  OG1   . THR   F 3 269 ? 23.099  103.108 -50.030 1.00 37.50  ? 562  THR   D OG1   1 
ATOM   7534  C  CG2   . THR   F 3 269 ? 25.245  102.829 -49.042 1.00 31.98  ? 562  THR   D CG2   1 
ATOM   7535  N  N     . ARG   F 3 270 ? 22.544  104.581 -47.737 1.00 34.29  ? 563  ARG   D N     1 
ATOM   7536  C  CA    . ARG   F 3 270 ? 22.007  104.276 -46.420 1.00 33.65  ? 563  ARG   D CA    1 
ATOM   7537  C  C     . ARG   F 3 270 ? 21.869  102.761 -46.285 1.00 34.08  ? 563  ARG   D C     1 
ATOM   7538  O  O     . ARG   F 3 270 ? 21.501  102.093 -47.247 1.00 36.66  ? 563  ARG   D O     1 
ATOM   7539  C  CB    . ARG   F 3 270 ? 20.670  104.983 -46.270 1.00 37.26  ? 563  ARG   D CB    1 
ATOM   7540  C  CG    . ARG   F 3 270 ? 20.741  106.437 -46.707 1.00 39.27  ? 563  ARG   D CG    1 
ATOM   7541  C  CD    . ARG   F 3 270 ? 19.409  107.151 -46.651 1.00 38.21  ? 563  ARG   D CD    1 
ATOM   7542  N  NE    . ARG   F 3 270 ? 18.792  107.134 -45.337 1.00 39.71  ? 563  ARG   D NE    1 
ATOM   7543  C  CZ    . ARG   F 3 270 ? 17.476  107.047 -45.148 1.00 40.94  ? 563  ARG   D CZ    1 
ATOM   7544  N  NH1   . ARG   F 3 270 ? 16.669  106.900 -46.184 1.00 42.68  ? 563  ARG   D NH1   1 
ATOM   7545  N  NH2   . ARG   F 3 270 ? 16.976  107.121 -43.930 1.00 40.91  ? 563  ARG   D NH2   1 
ATOM   7546  N  N     . PHE   F 3 271 ? 22.285  102.241 -45.123 1.00 33.48  ? 564  PHE   D N     1 
ATOM   7547  C  CA    . PHE   F 3 271 ? 22.099  100.860 -44.727 1.00 31.13  ? 564  PHE   D CA    1 
ATOM   7548  C  C     . PHE   F 3 271 ? 20.976  100.830 -43.705 1.00 29.00  ? 564  PHE   D C     1 
ATOM   7549  O  O     . PHE   F 3 271 ? 21.179  101.232 -42.570 1.00 30.15  ? 564  PHE   D O     1 
ATOM   7550  C  CB    . PHE   F 3 271 ? 23.417  100.286 -44.192 1.00 29.85  ? 564  PHE   D CB    1 
ATOM   7551  C  CG    . PHE   F 3 271 ? 24.403  100.026 -45.299 1.00 29.89  ? 564  PHE   D CG    1 
ATOM   7552  C  CD1   . PHE   F 3 271 ? 24.149  99.038  -46.236 1.00 30.31  ? 564  PHE   D CD1   1 
ATOM   7553  C  CD2   . PHE   F 3 271 ? 25.527  100.826 -45.452 1.00 28.40  ? 564  PHE   D CD2   1 
ATOM   7554  C  CE1   . PHE   F 3 271 ? 25.042  98.807  -47.269 1.00 33.54  ? 564  PHE   D CE1   1 
ATOM   7555  C  CE2   . PHE   F 3 271 ? 26.405  100.611 -46.496 1.00 28.19  ? 564  PHE   D CE2   1 
ATOM   7556  C  CZ    . PHE   F 3 271 ? 26.158  99.607  -47.407 1.00 31.93  ? 564  PHE   D CZ    1 
ATOM   7557  N  N     . ASN   F 3 272 ? 19.790  100.426 -44.154 1.00 28.62  ? 565  ASN   D N     1 
ATOM   7558  C  CA    . ASN   F 3 272 ? 18.592  100.449 -43.334 1.00 28.31  ? 565  ASN   D CA    1 
ATOM   7559  C  C     . ASN   F 3 272 ? 18.591  99.204  -42.450 1.00 28.51  ? 565  ASN   D C     1 
ATOM   7560  O  O     . ASN   F 3 272 ? 18.706  98.083  -42.942 1.00 23.68  ? 565  ASN   D O     1 
ATOM   7561  C  CB    . ASN   F 3 272 ? 17.350  100.564 -44.210 1.00 28.41  ? 565  ASN   D CB    1 
ATOM   7562  C  CG    . ASN   F 3 272 ? 17.474  101.689 -45.213 1.00 30.02  ? 565  ASN   D CG    1 
ATOM   7563  O  OD1   . ASN   F 3 272 ? 17.671  102.841 -44.833 1.00 31.72  ? 565  ASN   D OD1   1 
ATOM   7564  N  ND2   . ASN   F 3 272 ? 17.404  101.358 -46.493 1.00 29.86  ? 565  ASN   D ND2   1 
ATOM   7565  N  N     . GLN   F 3 273 ? 18.522  99.416  -41.130 1.00 29.38  ? 566  GLN   D N     1 
ATOM   7566  C  CA    . GLN   F 3 273 ? 18.770  98.331  -40.197 1.00 29.10  ? 566  GLN   D CA    1 
ATOM   7567  C  C     . GLN   F 3 273 ? 17.469  97.697  -39.697 1.00 29.89  ? 566  GLN   D C     1 
ATOM   7568  O  O     . GLN   F 3 273 ? 17.554  96.690  -39.006 1.00 29.53  ? 566  GLN   D O     1 
ATOM   7569  C  CB    . GLN   F 3 273 ? 19.614  98.838  -39.028 1.00 27.94  ? 566  GLN   D CB    1 
ATOM   7570  C  CG    . GLN   F 3 273 ? 20.141  97.720  -38.152 1.00 27.01  ? 566  GLN   D CG    1 
ATOM   7571  C  CD    . GLN   F 3 273 ? 21.126  98.213  -37.129 1.00 29.46  ? 566  GLN   D CD    1 
ATOM   7572  O  OE1   . GLN   F 3 273 ? 21.437  99.410  -37.059 1.00 33.25  ? 566  GLN   D OE1   1 
ATOM   7573  N  NE2   . GLN   F 3 273 ? 21.573  97.292  -36.287 1.00 26.09  ? 566  GLN   D NE2   1 
ATOM   7574  N  N     . THR   F 3 274 ? 16.288  98.284  -39.999 1.00 28.61  ? 567  THR   D N     1 
ATOM   7575  C  CA    . THR   F 3 274 ? 15.004  97.729  -39.575 1.00 26.72  ? 567  THR   D CA    1 
ATOM   7576  C  C     . THR   F 3 274 ? 14.001  97.786  -40.721 1.00 27.87  ? 567  THR   D C     1 
ATOM   7577  O  O     . THR   F 3 274 ? 12.932  98.372  -40.574 1.00 31.01  ? 567  THR   D O     1 
ATOM   7578  C  CB    . THR   F 3 274 ? 14.430  98.466  -38.356 1.00 27.26  ? 567  THR   D CB    1 
ATOM   7579  O  OG1   . THR   F 3 274 ? 14.022  99.796  -38.696 1.00 30.54  ? 567  THR   D OG1   1 
ATOM   7580  C  CG2   . THR   F 3 274 ? 15.417  98.564  -37.218 1.00 26.17  ? 567  THR   D CG2   1 
ATOM   7581  N  N     . ALA   F 3 275 ? 14.344  97.162  -41.852 1.00 26.55  ? 568  ALA   D N     1 
ATOM   7582  C  CA    . ALA   F 3 275 ? 13.583  97.335  -43.082 1.00 28.61  ? 568  ALA   D CA    1 
ATOM   7583  C  C     . ALA   F 3 275 ? 13.091  96.011  -43.681 1.00 31.75  ? 568  ALA   D C     1 
ATOM   7584  O  O     . ALA   F 3 275 ? 12.258  96.057  -44.585 1.00 38.73  ? 568  ALA   D O     1 
ATOM   7585  C  CB    . ALA   F 3 275 ? 14.431  98.086  -44.091 1.00 27.34  ? 568  ALA   D CB    1 
ATOM   7586  N  N     . THR   F 3 276 ? 13.585  94.845  -43.209 1.00 32.36  ? 569  THR   D N     1 
ATOM   7587  C  CA    . THR   F 3 276 ? 13.244  93.556  -43.811 1.00 30.39  ? 569  THR   D CA    1 
ATOM   7588  C  C     . THR   F 3 276 ? 12.599  92.600  -42.805 1.00 29.53  ? 569  THR   D C     1 
ATOM   7589  O  O     . THR   F 3 276 ? 12.810  92.735  -41.599 1.00 30.17  ? 569  THR   D O     1 
ATOM   7590  C  CB    . THR   F 3 276 ? 14.479  92.893  -44.441 1.00 29.73  ? 569  THR   D CB    1 
ATOM   7591  O  OG1   . THR   F 3 276 ? 15.334  92.410  -43.405 1.00 28.60  ? 569  THR   D OG1   1 
ATOM   7592  C  CG2   . THR   F 3 276 ? 15.219  93.834  -45.362 1.00 29.56  ? 569  THR   D CG2   1 
ATOM   7593  N  N     . ALA   F 3 277 ? 11.855  91.604  -43.324 1.00 31.19  ? 570  ALA   D N     1 
ATOM   7594  C  CA    . ALA   F 3 277 ? 11.131  90.646  -42.489 1.00 33.58  ? 570  ALA   D CA    1 
ATOM   7595  C  C     . ALA   F 3 277 ? 12.026  89.492  -42.032 1.00 30.68  ? 570  ALA   D C     1 
ATOM   7596  O  O     . ALA   F 3 277 ? 11.617  88.660  -41.223 1.00 31.10  ? 570  ALA   D O     1 
ATOM   7597  C  CB    . ALA   F 3 277 ? 9.945   90.096  -43.244 1.00 35.15  ? 570  ALA   D CB    1 
ATOM   7598  N  N     . THR   F 3 278 ? 13.248  89.428  -42.561 1.00 31.80  ? 571  THR   D N     1 
ATOM   7599  C  CA    . THR   F 3 278 ? 14.115  88.288  -42.325 1.00 29.00  ? 571  THR   D CA    1 
ATOM   7600  C  C     . THR   F 3 278 ? 15.324  88.623  -41.460 1.00 27.25  ? 571  THR   D C     1 
ATOM   7601  O  O     . THR   F 3 278 ? 16.009  87.706  -41.015 1.00 30.29  ? 571  THR   D O     1 
ATOM   7602  C  CB    . THR   F 3 278 ? 14.621  87.739  -43.655 1.00 30.05  ? 571  THR   D CB    1 
ATOM   7603  O  OG1   . THR   F 3 278 ? 15.261  88.828  -44.344 1.00 29.39  ? 571  THR   D OG1   1 
ATOM   7604  C  CG2   . THR   F 3 278 ? 13.485  87.098  -44.422 1.00 30.26  ? 571  THR   D CG2   1 
ATOM   7605  N  N     . GLY   F 3 279 ? 15.615  89.907  -41.240 1.00 27.26  ? 572  GLY   D N     1 
ATOM   7606  C  CA    . GLY   F 3 279 ? 16.827  90.275  -40.518 1.00 26.89  ? 572  GLY   D CA    1 
ATOM   7607  C  C     . GLY   F 3 279 ? 17.965  90.763  -41.414 1.00 26.74  ? 572  GLY   D C     1 
ATOM   7608  O  O     . GLY   F 3 279 ? 19.021  91.113  -40.911 1.00 26.94  ? 572  GLY   D O     1 
ATOM   7609  N  N     . ARG   F 3 280 ? 17.764  90.777  -42.740 1.00 30.98  ? 573  ARG   D N     1 
ATOM   7610  C  CA    . ARG   F 3 280 ? 18.719  91.396  -43.647 1.00 29.03  ? 573  ARG   D CA    1 
ATOM   7611  C  C     . ARG   F 3 280 ? 18.720  92.904  -43.452 1.00 27.93  ? 573  ARG   D C     1 
ATOM   7612  O  O     . ARG   F 3 280 ? 17.783  93.486  -42.891 1.00 28.85  ? 573  ARG   D O     1 
ATOM   7613  C  CB    . ARG   F 3 280 ? 18.425  91.150  -45.133 1.00 29.31  ? 573  ARG   D CB    1 
ATOM   7614  C  CG    . ARG   F 3 280 ? 18.702  89.734  -45.612 1.00 28.71  ? 573  ARG   D CG    1 
ATOM   7615  C  CD    . ARG   F 3 280 ? 19.303  89.723  -47.010 1.00 32.03  ? 573  ARG   D CD    1 
ATOM   7616  N  NE    . ARG   F 3 280 ? 18.940  88.511  -47.741 1.00 29.39  ? 573  ARG   D NE    1 
ATOM   7617  C  CZ    . ARG   F 3 280 ? 19.231  88.232  -49.004 1.00 27.59  ? 573  ARG   D CZ    1 
ATOM   7618  N  NH1   . ARG   F 3 280 ? 19.872  87.113  -49.316 1.00 27.01  ? 573  ARG   D NH1   1 
ATOM   7619  N  NH2   . ARG   F 3 280 ? 18.694  88.968  -49.958 1.00 28.23  ? 573  ARG   D NH2   1 
ATOM   7620  N  N     . LEU   F 3 281 ? 19.830  93.499  -43.891 1.00 26.19  ? 574  LEU   D N     1 
ATOM   7621  C  CA    . LEU   F 3 281 ? 19.893  94.930  -44.109 1.00 27.42  ? 574  LEU   D CA    1 
ATOM   7622  C  C     . LEU   F 3 281 ? 19.207  95.236  -45.431 1.00 26.84  ? 574  LEU   D C     1 
ATOM   7623  O  O     . LEU   F 3 281 ? 19.019  94.346  -46.257 1.00 27.52  ? 574  LEU   D O     1 
ATOM   7624  C  CB    . LEU   F 3 281 ? 21.355  95.366  -44.185 1.00 27.26  ? 574  LEU   D CB    1 
ATOM   7625  C  CG    . LEU   F 3 281 ? 22.206  95.143  -42.945 1.00 27.12  ? 574  LEU   D CG    1 
ATOM   7626  C  CD1   . LEU   F 3 281 ? 23.618  95.644  -43.213 1.00 29.44  ? 574  LEU   D CD1   1 
ATOM   7627  C  CD2   . LEU   F 3 281 ? 21.606  95.836  -41.731 1.00 29.46  ? 574  LEU   D CD2   1 
ATOM   7628  N  N     . SER   F 3 282 ? 18.836  96.503  -45.625 1.00 30.84  ? 575  SER   D N     1 
ATOM   7629  C  CA    . SER   F 3 282 ? 18.526  96.997  -46.960 1.00 32.48  ? 575  SER   D CA    1 
ATOM   7630  C  C     . SER   F 3 282 ? 19.425  98.199  -47.214 1.00 31.28  ? 575  SER   D C     1 
ATOM   7631  O  O     . SER   F 3 282 ? 20.134  98.632  -46.309 1.00 31.48  ? 575  SER   D O     1 
ATOM   7632  C  CB    . SER   F 3 282 ? 17.060  97.281  -47.168 1.00 31.88  ? 575  SER   D CB    1 
ATOM   7633  O  OG    . SER   F 3 282 ? 16.720  98.614  -46.818 1.00 34.63  ? 575  SER   D OG    1 
ATOM   7634  N  N     . SER   F 3 283 ? 19.491  98.631  -48.475 1.00 31.33  ? 576  SER   D N     1 
ATOM   7635  C  CA    . SER   F 3 283 ? 20.294  99.782  -48.862 1.00 30.77  ? 576  SER   D CA    1 
ATOM   7636  C  C     . SER   F 3 283 ? 19.432  100.654 -49.754 1.00 30.35  ? 576  SER   D C     1 
ATOM   7637  O  O     . SER   F 3 283 ? 18.683  100.124 -50.570 1.00 30.53  ? 576  SER   D O     1 
ATOM   7638  C  CB    . SER   F 3 283 ? 21.549  99.357  -49.567 1.00 31.45  ? 576  SER   D CB    1 
ATOM   7639  O  OG    . SER   F 3 283 ? 22.292  100.462 -50.039 1.00 33.09  ? 576  SER   D OG    1 
ATOM   7640  N  N     . SER   F 3 284 ? 19.519  101.971 -49.576 1.00 29.46  ? 577  SER   D N     1 
ATOM   7641  C  CA    . SER   F 3 284 ? 18.709  102.869 -50.375 1.00 31.22  ? 577  SER   D CA    1 
ATOM   7642  C  C     . SER   F 3 284 ? 19.409  104.217 -50.565 1.00 33.87  ? 577  SER   D C     1 
ATOM   7643  O  O     . SER   F 3 284 ? 20.353  104.540 -49.851 1.00 32.04  ? 577  SER   D O     1 
ATOM   7644  C  CB    . SER   F 3 284 ? 17.320  102.994 -49.778 1.00 32.01  ? 577  SER   D CB    1 
ATOM   7645  O  OG    . SER   F 3 284 ? 17.325  103.673 -48.534 1.00 30.21  ? 577  SER   D OG    1 
ATOM   7646  N  N     . ASP   F 3 285 ? 18.990  104.959 -51.610 1.00 38.98  ? 578  ASP   D N     1 
ATOM   7647  C  CA    . ASP   F 3 285 ? 19.298  106.381 -51.753 1.00 35.28  ? 578  ASP   D CA    1 
ATOM   7648  C  C     . ASP   F 3 285 ? 20.795  106.621 -51.971 1.00 32.97  ? 578  ASP   D C     1 
ATOM   7649  O  O     . ASP   F 3 285 ? 21.391  107.440 -51.269 1.00 35.46  ? 578  ASP   D O     1 
ATOM   7650  C  CB    . ASP   F 3 285 ? 18.778  107.145 -50.525 1.00 37.13  ? 578  ASP   D CB    1 
ATOM   7651  C  CG    . ASP   F 3 285 ? 17.295  106.924 -50.265 1.00 37.34  ? 578  ASP   D CG    1 
ATOM   7652  O  OD1   . ASP   F 3 285 ? 16.506  107.220 -51.165 1.00 36.57  ? 578  ASP   D OD1   1 
ATOM   7653  O  OD2   . ASP   F 3 285 ? 16.942  106.431 -49.175 1.00 45.24  ? 578  ASP   D OD2   1 
ATOM   7654  N  N     . PRO   F 3 286 ? 21.485  105.942 -52.927 1.00 32.21  ? 579  PRO   D N     1 
ATOM   7655  C  CA    . PRO   F 3 286 ? 20.921  104.888 -53.773 1.00 32.70  ? 579  PRO   D CA    1 
ATOM   7656  C  C     . PRO   F 3 286 ? 21.127  103.480 -53.215 1.00 30.67  ? 579  PRO   D C     1 
ATOM   7657  O  O     . PRO   F 3 286 ? 21.802  103.313 -52.203 1.00 32.61  ? 579  PRO   D O     1 
ATOM   7658  C  CB    . PRO   F 3 286 ? 21.776  105.064 -55.033 1.00 32.07  ? 579  PRO   D CB    1 
ATOM   7659  C  CG    . PRO   F 3 286 ? 23.147  105.287 -54.462 1.00 33.63  ? 579  PRO   D CG    1 
ATOM   7660  C  CD    . PRO   F 3 286 ? 22.906  106.170 -53.250 1.00 32.97  ? 579  PRO   D CD    1 
ATOM   7661  N  N     . ASN   F 3 287 ? 20.567  102.478 -53.904 1.00 28.91  ? 580  ASN   D N     1 
ATOM   7662  C  CA    . ASN   F 3 287 ? 20.652  101.101 -53.450 1.00 27.67  ? 580  ASN   D CA    1 
ATOM   7663  C  C     . ASN   F 3 287 ? 21.958  100.500 -53.950 1.00 26.81  ? 580  ASN   D C     1 
ATOM   7664  O  O     . ASN   F 3 287 ? 21.992  99.944  -55.049 1.00 29.75  ? 580  ASN   D O     1 
ATOM   7665  C  CB    . ASN   F 3 287 ? 19.442  100.262 -53.888 1.00 27.93  ? 580  ASN   D CB    1 
ATOM   7666  C  CG    . ASN   F 3 287 ? 19.505  98.833  -53.371 1.00 28.24  ? 580  ASN   D CG    1 
ATOM   7667  O  OD1   . ASN   F 3 287 ? 20.479  98.461  -52.720 1.00 27.79  ? 580  ASN   D OD1   1 
ATOM   7668  N  ND2   . ASN   F 3 287 ? 18.500  98.016  -53.663 1.00 26.58  ? 580  ASN   D ND2   1 
ATOM   7669  N  N     . LEU   F 3 288 ? 23.002  100.540 -53.112 1.00 25.67  ? 581  LEU   D N     1 
ATOM   7670  C  CA    . LEU   F 3 288 ? 24.303  99.984  -53.479 1.00 27.17  ? 581  LEU   D CA    1 
ATOM   7671  C  C     . LEU   F 3 288 ? 24.392  98.476  -53.216 1.00 30.29  ? 581  LEU   D C     1 
ATOM   7672  O  O     . LEU   F 3 288 ? 25.492  97.907  -53.291 1.00 30.30  ? 581  LEU   D O     1 
ATOM   7673  C  CB    . LEU   F 3 288 ? 25.413  100.740 -52.743 1.00 26.30  ? 581  LEU   D CB    1 
ATOM   7674  C  CG    . LEU   F 3 288 ? 25.591  102.204 -53.181 1.00 26.24  ? 581  LEU   D CG    1 
ATOM   7675  C  CD1   . LEU   F 3 288 ? 26.873  102.807 -52.626 1.00 26.27  ? 581  LEU   D CD1   1 
ATOM   7676  C  CD2   . LEU   F 3 288 ? 25.565  102.327 -54.698 1.00 27.87  ? 581  LEU   D CD2   1 
ATOM   7677  N  N     . GLN   F 3 289 ? 23.229  97.835  -52.986 1.00 28.79  ? 582  GLN   D N     1 
ATOM   7678  C  CA    . GLN   F 3 289 ? 23.138  96.384  -52.933 1.00 30.62  ? 582  GLN   D CA    1 
ATOM   7679  C  C     . GLN   F 3 289 ? 22.498  95.858  -54.217 1.00 28.94  ? 582  GLN   D C     1 
ATOM   7680  O  O     . GLN   F 3 289 ? 22.130  94.687  -54.261 1.00 29.32  ? 582  GLN   D O     1 
ATOM   7681  C  CB    . GLN   F 3 289 ? 22.347  95.879  -51.705 1.00 27.42  ? 582  GLN   D CB    1 
ATOM   7682  C  CG    . GLN   F 3 289 ? 22.957  96.228  -50.351 1.00 26.68  ? 582  GLN   D CG    1 
ATOM   7683  C  CD    . GLN   F 3 289 ? 22.174  95.713  -49.158 1.00 28.70  ? 582  GLN   D CD    1 
ATOM   7684  O  OE1   . GLN   F 3 289 ? 20.937  95.633  -49.175 1.00 24.39  ? 582  GLN   D OE1   1 
ATOM   7685  N  NE2   . GLN   F 3 289 ? 22.904  95.326  -48.116 1.00 25.06  ? 582  GLN   D NE2   1 
ATOM   7686  N  N     . SER   F 3 290 ? 22.372  96.716  -55.244 1.00 30.81  ? 583  SER   D N     1 
ATOM   7687  C  CA    . SER   F 3 290 ? 21.707  96.355  -56.488 1.00 31.27  ? 583  SER   D CA    1 
ATOM   7688  C  C     . SER   F 3 290 ? 22.552  96.718  -57.707 1.00 32.07  ? 583  SER   D C     1 
ATOM   7689  O  O     . SER   F 3 290 ? 22.026  96.761  -58.817 1.00 34.29  ? 583  SER   D O     1 
ATOM   7690  C  CB    . SER   F 3 290 ? 20.362  97.016  -56.595 1.00 34.90  ? 583  SER   D CB    1 
ATOM   7691  O  OG    . SER   F 3 290 ? 20.518  98.421  -56.811 1.00 37.39  ? 583  SER   D OG    1 
ATOM   7692  N  N     . ILE   F 3 291 ? 23.855  96.960  -57.518 1.00 31.16  ? 584  ILE   D N     1 
ATOM   7693  C  CA    . ILE   F 3 291 ? 24.706  97.363  -58.629 1.00 31.55  ? 584  ILE   D CA    1 
ATOM   7694  C  C     . ILE   F 3 291 ? 24.839  96.205  -59.625 1.00 32.99  ? 584  ILE   D C     1 
ATOM   7695  O  O     . ILE   F 3 291 ? 25.211  95.101  -59.238 1.00 32.49  ? 584  ILE   D O     1 
ATOM   7696  C  CB    . ILE   F 3 291 ? 26.086  97.827  -58.143 1.00 30.08  ? 584  ILE   D CB    1 
ATOM   7697  C  CG1   . ILE   F 3 291 ? 25.996  99.003  -57.160 1.00 28.83  ? 584  ILE   D CG1   1 
ATOM   7698  C  CG2   . ILE   F 3 291 ? 26.990  98.124  -59.328 1.00 30.61  ? 584  ILE   D CG2   1 
ATOM   7699  C  CD1   . ILE   F 3 291 ? 25.081  100.100 -57.582 1.00 29.45  ? 584  ILE   D CD1   1 
ATOM   7700  N  N     . PRO   F 3 292 ? 24.576  96.428  -60.938 1.00 32.98  ? 585  PRO   D N     1 
ATOM   7701  C  CA    . PRO   F 3 292 ? 24.698  95.375  -61.947 1.00 31.40  ? 585  PRO   D CA    1 
ATOM   7702  C  C     . PRO   F 3 292 ? 26.042  94.674  -61.907 1.00 32.08  ? 585  PRO   D C     1 
ATOM   7703  O  O     . PRO   F 3 292 ? 27.042  95.285  -61.534 1.00 30.98  ? 585  PRO   D O     1 
ATOM   7704  C  CB    . PRO   F 3 292 ? 24.500  96.133  -63.259 1.00 32.62  ? 585  PRO   D CB    1 
ATOM   7705  C  CG    . PRO   F 3 292 ? 23.545  97.240  -62.860 1.00 32.75  ? 585  PRO   D CG    1 
ATOM   7706  C  CD    . PRO   F 3 292 ? 24.064  97.686  -61.512 1.00 33.22  ? 585  PRO   D CD    1 
ATOM   7707  N  N     . VAL   F 3 293 ? 26.079  93.412  -62.342 1.00 36.16  ? 586  VAL   D N     1 
ATOM   7708  C  CA    . VAL   F 3 293 ? 27.333  92.606  -62.292 1.00 37.31  ? 586  VAL   D CA    1 
ATOM   7709  C  C     . VAL   F 3 293 ? 27.211  91.379  -63.179 1.00 40.31  ? 586  VAL   D C     1 
ATOM   7710  O  O     . VAL   F 3 293 ? 28.230  90.734  -63.430 1.00 49.05  ? 586  VAL   D O     1 
ATOM   7711  C  CB    . VAL   F 3 293 ? 27.547  92.118  -60.849 1.00 34.39  ? 586  VAL   D CB    1 
ATOM   7712  C  CG1   . VAL   F 3 293 ? 26.432  91.189  -60.397 1.00 35.48  ? 586  VAL   D CG1   1 
ATOM   7713  C  CG2   . VAL   F 3 293 ? 28.908  91.480  -60.638 1.00 33.38  ? 586  VAL   D CG2   1 
ATOM   7714  N  N     . ARG   F 3 294 ? 26.044  91.128  -63.731 1.00 43.57  ? 587  ARG   D N     1 
ATOM   7715  C  CA    . ARG   F 3 294 ? 25.789  89.836  -64.337 1.00 50.21  ? 587  ARG   D CA    1 
ATOM   7716  C  C     . ARG   F 3 294 ? 26.084  89.864  -65.841 1.00 53.52  ? 587  ARG   D C     1 
ATOM   7717  O  O     . ARG   F 3 294 ? 26.806  89.006  -66.338 1.00 59.16  ? 587  ARG   D O     1 
ATOM   7718  C  CB    . ARG   F 3 294 ? 24.329  89.533  -64.016 1.00 44.68  ? 587  ARG   D CB    1 
ATOM   7719  C  CG    . ARG   F 3 294 ? 23.787  88.260  -64.636 1.00 53.66  ? 587  ARG   D CG    1 
ATOM   7720  C  CD    . ARG   F 3 294 ? 22.357  88.053  -64.195 1.00 56.13  ? 587  ARG   D CD    1 
ATOM   7721  N  NE    . ARG   F 3 294 ? 21.525  89.225  -64.396 1.00 59.84  ? 587  ARG   D NE    1 
ATOM   7722  C  CZ    . ARG   F 3 294 ? 20.631  89.369  -65.365 1.00 60.34  ? 587  ARG   D CZ    1 
ATOM   7723  N  NH1   . ARG   F 3 294 ? 20.478  88.422  -66.274 1.00 56.92  ? 587  ARG   D NH1   1 
ATOM   7724  N  NH2   . ARG   F 3 294 ? 19.919  90.482  -65.421 1.00 56.88  ? 587  ARG   D NH2   1 
ATOM   7725  N  N     . THR   F 3 295 ? 25.478  90.830  -66.554 1.00 51.93  ? 588  THR   D N     1 
ATOM   7726  C  CA    . THR   F 3 295 ? 25.614  90.965  -67.996 1.00 45.40  ? 588  THR   D CA    1 
ATOM   7727  C  C     . THR   F 3 295 ? 26.897  91.711  -68.340 1.00 43.30  ? 588  THR   D C     1 
ATOM   7728  O  O     . THR   F 3 295 ? 27.484  92.386  -67.492 1.00 41.66  ? 588  THR   D O     1 
ATOM   7729  C  CB    . THR   F 3 295 ? 24.449  91.736  -68.627 1.00 40.39  ? 588  THR   D CB    1 
ATOM   7730  O  OG1   . THR   F 3 295 ? 24.525  93.086  -68.153 1.00 39.48  ? 588  THR   D OG1   1 
ATOM   7731  C  CG2   . THR   F 3 295 ? 23.106  91.100  -68.350 1.00 39.84  ? 588  THR   D CG2   1 
ATOM   7732  N  N     . PRO   F 3 296 ? 27.365  91.600  -69.603 1.00 45.43  ? 589  PRO   D N     1 
ATOM   7733  C  CA    . PRO   F 3 296 ? 28.547  92.343  -70.046 1.00 44.44  ? 589  PRO   D CA    1 
ATOM   7734  C  C     . PRO   F 3 296 ? 28.537  93.835  -69.710 1.00 40.84  ? 589  PRO   D C     1 
ATOM   7735  O  O     . PRO   F 3 296 ? 29.552  94.363  -69.247 1.00 41.44  ? 589  PRO   D O     1 
ATOM   7736  C  CB    . PRO   F 3 296 ? 28.558  92.035  -71.551 1.00 47.65  ? 589  PRO   D CB    1 
ATOM   7737  C  CG    . PRO   F 3 296 ? 28.033  90.607  -71.610 1.00 46.68  ? 589  PRO   D CG    1 
ATOM   7738  C  CD    . PRO   F 3 296 ? 26.878  90.653  -70.630 1.00 47.35  ? 589  PRO   D CD    1 
ATOM   7739  N  N     . LEU   F 3 297 ? 27.401  94.511  -69.925 1.00 39.64  ? 590  LEU   D N     1 
ATOM   7740  C  CA    . LEU   F 3 297 ? 27.293  95.920  -69.565 1.00 40.33  ? 590  LEU   D CA    1 
ATOM   7741  C  C     . LEU   F 3 297 ? 27.311  96.104  -68.043 1.00 41.47  ? 590  LEU   D C     1 
ATOM   7742  O  O     . LEU   F 3 297 ? 27.831  97.102  -67.529 1.00 37.61  ? 590  LEU   D O     1 
ATOM   7743  C  CB    . LEU   F 3 297 ? 26.005  96.498  -70.157 1.00 45.14  ? 590  LEU   D CB    1 
ATOM   7744  C  CG    . LEU   F 3 297 ? 25.751  97.967  -69.810 1.00 48.38  ? 590  LEU   D CG    1 
ATOM   7745  C  CD1   . LEU   F 3 297 ? 26.903  98.834  -70.293 1.00 49.93  ? 590  LEU   D CD1   1 
ATOM   7746  C  CD2   . LEU   F 3 297 ? 24.432  98.452  -70.403 1.00 53.80  ? 590  LEU   D CD2   1 
ATOM   7747  N  N     . GLY   F 3 298 ? 26.700  95.144  -67.329 1.00 40.29  ? 591  GLY   D N     1 
ATOM   7748  C  CA    . GLY   F 3 298 ? 26.665  95.183  -65.886 1.00 37.95  ? 591  GLY   D CA    1 
ATOM   7749  C  C     . GLY   F 3 298 ? 28.069  95.198  -65.310 1.00 35.00  ? 591  GLY   D C     1 
ATOM   7750  O  O     . GLY   F 3 298 ? 28.345  95.915  -64.350 1.00 38.71  ? 591  GLY   D O     1 
ATOM   7751  N  N     . GLN   F 3 299 ? 28.958  94.421  -65.929 1.00 39.36  ? 592  GLN   D N     1 
ATOM   7752  C  CA    . GLN   F 3 299 ? 30.330  94.291  -65.448 1.00 44.35  ? 592  GLN   D CA    1 
ATOM   7753  C  C     . GLN   F 3 299 ? 31.084  95.606  -65.621 1.00 45.76  ? 592  GLN   D C     1 
ATOM   7754  O  O     . GLN   F 3 299 ? 31.998  95.919  -64.859 1.00 50.54  ? 592  GLN   D O     1 
ATOM   7755  C  CB    . GLN   F 3 299 ? 31.024  93.127  -66.160 1.00 46.47  ? 592  GLN   D CB    1 
ATOM   7756  C  CG    . GLN   F 3 299 ? 30.472  91.776  -65.731 1.00 54.11  ? 592  GLN   D CG    1 
ATOM   7757  C  CD    . GLN   F 3 299 ? 30.891  90.631  -66.617 1.00 65.35  ? 592  GLN   D CD    1 
ATOM   7758  O  OE1   . GLN   F 3 299 ? 31.701  90.784  -67.531 1.00 79.51  ? 592  GLN   D OE1   1 
ATOM   7759  N  NE2   . GLN   F 3 299 ? 30.344  89.457  -66.341 1.00 70.80  ? 592  GLN   D NE2   1 
ATOM   7760  N  N     . ARG   F 3 300 ? 30.694  96.392  -66.625 1.00 48.96  ? 593  ARG   D N     1 
ATOM   7761  C  CA    . ARG   F 3 300 ? 31.373  97.651  -66.888 1.00 50.55  ? 593  ARG   D CA    1 
ATOM   7762  C  C     . ARG   F 3 300 ? 30.984  98.686  -65.829 1.00 44.36  ? 593  ARG   D C     1 
ATOM   7763  O  O     . ARG   F 3 300 ? 31.782  99.548  -65.481 1.00 42.88  ? 593  ARG   D O     1 
ATOM   7764  C  CB    . ARG   F 3 300 ? 31.081  98.050  -68.335 1.00 56.37  ? 593  ARG   D CB    1 
ATOM   7765  C  CG    . ARG   F 3 300 ? 31.513  96.969  -69.319 1.00 63.99  ? 593  ARG   D CG    1 
ATOM   7766  C  CD    . ARG   F 3 300 ? 31.251  97.347  -70.755 1.00 65.87  ? 593  ARG   D CD    1 
ATOM   7767  N  NE    . ARG   F 3 300 ? 31.978  98.570  -71.060 1.00 64.43  ? 593  ARG   D NE    1 
ATOM   7768  C  CZ    . ARG   F 3 300 ? 31.739  99.315  -72.124 1.00 56.88  ? 593  ARG   D CZ    1 
ATOM   7769  N  NH1   . ARG   F 3 300 ? 30.857  98.891  -73.012 1.00 50.53  ? 593  ARG   D NH1   1 
ATOM   7770  N  NH2   . ARG   F 3 300 ? 32.369  100.468 -72.279 1.00 49.24  ? 593  ARG   D NH2   1 
ATOM   7771  N  N     . ILE   F 3 301 ? 29.771  98.579  -65.280 1.00 40.91  ? 594  ILE   D N     1 
ATOM   7772  C  CA    . ILE   F 3 301 ? 29.335  99.465  -64.205 1.00 38.60  ? 594  ILE   D CA    1 
ATOM   7773  C  C     . ILE   F 3 301 ? 30.155  99.191  -62.932 1.00 38.97  ? 594  ILE   D C     1 
ATOM   7774  O  O     . ILE   F 3 301 ? 30.597  100.135 -62.275 1.00 37.75  ? 594  ILE   D O     1 
ATOM   7775  C  CB    . ILE   F 3 301 ? 27.803  99.353  -64.016 1.00 35.81  ? 594  ILE   D CB    1 
ATOM   7776  C  CG1   . ILE   F 3 301 ? 27.090  99.772  -65.306 1.00 34.58  ? 594  ILE   D CG1   1 
ATOM   7777  C  CG2   . ILE   F 3 301 ? 27.311  100.153 -62.811 1.00 37.33  ? 594  ILE   D CG2   1 
ATOM   7778  C  CD1   . ILE   F 3 301 ? 25.589  99.811  -65.227 1.00 33.92  ? 594  ILE   D CD1   1 
ATOM   7779  N  N     . ARG   F 3 302 ? 30.408  97.912  -62.601 1.00 38.50  ? 595  ARG   D N     1 
ATOM   7780  C  CA    . ARG   F 3 302 ? 31.209  97.570  -61.428 1.00 39.67  ? 595  ARG   D CA    1 
ATOM   7781  C  C     . ARG   F 3 302 ? 32.619  98.135  -61.543 1.00 40.81  ? 595  ARG   D C     1 
ATOM   7782  O  O     . ARG   F 3 302 ? 33.263  98.380  -60.522 1.00 42.11  ? 595  ARG   D O     1 
ATOM   7783  C  CB    . ARG   F 3 302 ? 31.389  96.059  -61.242 1.00 43.80  ? 595  ARG   D CB    1 
ATOM   7784  C  CG    . ARG   F 3 302 ? 30.143  95.306  -60.806 1.00 43.88  ? 595  ARG   D CG    1 
ATOM   7785  C  CD    . ARG   F 3 302 ? 29.768  95.634  -59.380 1.00 41.65  ? 595  ARG   D CD    1 
ATOM   7786  N  NE    . ARG   F 3 302 ? 28.501  95.003  -59.027 1.00 41.35  ? 595  ARG   D NE    1 
ATOM   7787  C  CZ    . ARG   F 3 302 ? 28.366  94.102  -58.067 1.00 36.85  ? 595  ARG   D CZ    1 
ATOM   7788  N  NH1   . ARG   F 3 302 ? 29.450  93.623  -57.484 1.00 35.85  ? 595  ARG   D NH1   1 
ATOM   7789  N  NH2   . ARG   F 3 302 ? 27.159  93.688  -57.711 1.00 38.12  ? 595  ARG   D NH2   1 
ATOM   7790  N  N     . ARG   F 3 303 ? 33.104  98.294  -62.779 1.00 40.73  ? 596  ARG   D N     1 
ATOM   7791  C  CA    . ARG   F 3 303 ? 34.423  98.860  -63.032 1.00 44.26  ? 596  ARG   D CA    1 
ATOM   7792  C  C     . ARG   F 3 303 ? 34.495  100.303 -62.519 1.00 43.22  ? 596  ARG   D C     1 
ATOM   7793  O  O     . ARG   F 3 303 ? 35.580  100.818 -62.238 1.00 45.42  ? 596  ARG   D O     1 
ATOM   7794  C  CB    . ARG   F 3 303 ? 34.697  98.862  -64.536 1.00 53.94  ? 596  ARG   D CB    1 
ATOM   7795  C  CG    . ARG   F 3 303 ? 36.144  98.619  -64.936 1.00 65.02  ? 596  ARG   D CG    1 
ATOM   7796  C  CD    . ARG   F 3 303 ? 36.372  97.143  -65.245 1.00 77.66  ? 596  ARG   D CD    1 
ATOM   7797  N  NE    . ARG   F 3 303 ? 37.154  96.940  -66.461 1.00 80.90  ? 596  ARG   D NE    1 
ATOM   7798  C  CZ    . ARG   F 3 303 ? 36.627  96.674  -67.653 1.00 89.34  ? 596  ARG   D CZ    1 
ATOM   7799  N  NH1   . ARG   F 3 303 ? 35.396  96.197  -67.750 1.00 83.60  ? 596  ARG   D NH1   1 
ATOM   7800  N  NH2   . ARG   F 3 303 ? 37.335  96.901  -68.747 1.00 91.79  ? 596  ARG   D NH2   1 
ATOM   7801  N  N     . ALA   F 3 304 ? 33.331  100.960 -62.418 1.00 39.24  ? 597  ALA   D N     1 
ATOM   7802  C  CA    . ALA   F 3 304 ? 33.260  102.360 -62.031 1.00 39.83  ? 597  ALA   D CA    1 
ATOM   7803  C  C     . ALA   F 3 304 ? 33.398  102.536 -60.520 1.00 38.65  ? 597  ALA   D C     1 
ATOM   7804  O  O     . ALA   F 3 304 ? 33.561  103.659 -60.063 1.00 35.63  ? 597  ALA   D O     1 
ATOM   7805  C  CB    . ALA   F 3 304 ? 31.968  102.966 -62.513 1.00 42.08  ? 597  ALA   D CB    1 
ATOM   7806  N  N     . PHE   F 3 305 ? 33.299  101.447 -59.745 1.00 35.89  ? 598  PHE   D N     1 
ATOM   7807  C  CA    . PHE   F 3 305 ? 33.479  101.524 -58.306 1.00 32.14  ? 598  PHE   D CA    1 
ATOM   7808  C  C     . PHE   F 3 305 ? 34.946  101.246 -57.978 1.00 32.81  ? 598  PHE   D C     1 
ATOM   7809  O  O     . PHE   F 3 305 ? 35.406  100.122 -58.151 1.00 34.89  ? 598  PHE   D O     1 
ATOM   7810  C  CB    . PHE   F 3 305 ? 32.503  100.555 -57.636 1.00 30.58  ? 598  PHE   D CB    1 
ATOM   7811  C  CG    . PHE   F 3 305 ? 31.068  101.016 -57.674 1.00 29.80  ? 598  PHE   D CG    1 
ATOM   7812  C  CD1   . PHE   F 3 305 ? 30.311  100.876 -58.824 1.00 29.33  ? 598  PHE   D CD1   1 
ATOM   7813  C  CD2   . PHE   F 3 305 ? 30.499  101.649 -56.580 1.00 28.35  ? 598  PHE   D CD2   1 
ATOM   7814  C  CE1   . PHE   F 3 305 ? 29.004  101.327 -58.875 1.00 28.10  ? 598  PHE   D CE1   1 
ATOM   7815  C  CE2   . PHE   F 3 305 ? 29.191  102.092 -56.630 1.00 28.15  ? 598  PHE   D CE2   1 
ATOM   7816  C  CZ    . PHE   F 3 305 ? 28.444  101.935 -57.776 1.00 27.88  ? 598  PHE   D CZ    1 
ATOM   7817  N  N     . ILE   F 3 306 ? 35.669  102.275 -57.523 1.00 33.42  ? 599  ILE   D N     1 
ATOM   7818  C  CA    . ILE   F 3 306 ? 37.124  102.256 -57.456 1.00 36.35  ? 599  ILE   D CA    1 
ATOM   7819  C  C     . ILE   F 3 306 ? 37.569  102.633 -56.047 1.00 36.15  ? 599  ILE   D C     1 
ATOM   7820  O  O     . ILE   F 3 306 ? 36.759  103.102 -55.247 1.00 40.47  ? 599  ILE   D O     1 
ATOM   7821  C  CB    . ILE   F 3 306 ? 37.766  103.195 -58.504 1.00 37.15  ? 599  ILE   D CB    1 
ATOM   7822  C  CG1   . ILE   F 3 306 ? 37.280  104.642 -58.374 1.00 40.44  ? 599  ILE   D CG1   1 
ATOM   7823  C  CG2   . ILE   F 3 306 ? 37.553  102.659 -59.909 1.00 38.14  ? 599  ILE   D CG2   1 
ATOM   7824  C  CD1   . ILE   F 3 306 ? 38.144  105.663 -59.109 1.00 39.56  ? 599  ILE   D CD1   1 
ATOM   7825  N  N     . ALA   F 3 307 ? 38.862  102.412 -55.766 1.00 35.46  ? 600  ALA   D N     1 
ATOM   7826  C  CA    . ALA   F 3 307 ? 39.468  102.802 -54.503 1.00 35.82  ? 600  ALA   D CA    1 
ATOM   7827  C  C     . ALA   F 3 307 ? 40.070  104.197 -54.600 1.00 35.29  ? 600  ALA   D C     1 
ATOM   7828  O  O     . ALA   F 3 307 ? 40.363  104.674 -55.691 1.00 38.94  ? 600  ALA   D O     1 
ATOM   7829  C  CB    . ALA   F 3 307 ? 40.514  101.802 -54.111 1.00 35.89  ? 600  ALA   D CB    1 
ATOM   7830  N  N     . GLU   F 3 308 ? 40.209  104.844 -53.439 1.00 41.79  ? 601  GLU   D N     1 
ATOM   7831  C  CA    . GLU   F 3 308 ? 40.994  106.054 -53.283 1.00 48.64  ? 601  GLU   D CA    1 
ATOM   7832  C  C     . GLU   F 3 308 ? 42.402  105.794 -53.826 1.00 54.96  ? 601  GLU   D C     1 
ATOM   7833  O  O     . GLU   F 3 308 ? 42.844  104.646 -53.908 1.00 51.19  ? 601  GLU   D O     1 
ATOM   7834  C  CB    . GLU   F 3 308 ? 40.995  106.465 -51.809 1.00 49.80  ? 601  GLU   D CB    1 
ATOM   7835  C  CG    . GLU   F 3 308 ? 41.751  107.743 -51.521 1.00 50.22  ? 601  GLU   D CG    1 
ATOM   7836  C  CD    . GLU   F 3 308 ? 41.761  108.131 -50.055 1.00 54.91  ? 601  GLU   D CD    1 
ATOM   7837  O  OE1   . GLU   F 3 308 ? 40.695  108.030 -49.407 1.00 59.35  ? 601  GLU   D OE1   1 
ATOM   7838  O  OE2   . GLU   F 3 308 ? 42.820  108.566 -49.572 1.00 55.82  ? 601  GLU   D OE2   1 
ATOM   7839  N  N     . GLU   F 3 309 ? 43.084  106.866 -54.251 1.00 61.83  ? 602  GLU   D N     1 
ATOM   7840  C  CA    . GLU   F 3 309 ? 44.419  106.720 -54.817 1.00 61.73  ? 602  GLU   D CA    1 
ATOM   7841  C  C     . GLU   F 3 309 ? 45.343  106.267 -53.697 1.00 49.71  ? 602  GLU   D C     1 
ATOM   7842  O  O     . GLU   F 3 309 ? 45.381  106.873 -52.625 1.00 48.78  ? 602  GLU   D O     1 
ATOM   7843  C  CB    . GLU   F 3 309 ? 44.964  107.998 -55.476 1.00 72.31  ? 602  GLU   D CB    1 
ATOM   7844  C  CG    . GLU   F 3 309 ? 44.342  108.364 -56.825 1.00 82.93  ? 602  GLU   D CG    1 
ATOM   7845  C  CD    . GLU   F 3 309 ? 44.547  107.392 -57.982 1.00 88.76  ? 602  GLU   D CD    1 
ATOM   7846  O  OE1   . GLU   F 3 309 ? 45.725  107.090 -58.301 1.00 87.74  ? 602  GLU   D OE1   1 
ATOM   7847  O  OE2   . GLU   F 3 309 ? 43.526  106.949 -58.577 1.00 78.84  ? 602  GLU   D OE2   1 
ATOM   7848  N  N     . GLY   F 3 310 ? 46.057  105.174 -53.967 1.00 47.44  ? 603  GLY   D N     1 
ATOM   7849  C  CA    . GLY   F 3 310 ? 46.956  104.574 -53.002 1.00 48.43  ? 603  GLY   D CA    1 
ATOM   7850  C  C     . GLY   F 3 310 ? 46.310  103.415 -52.250 1.00 51.10  ? 603  GLY   D C     1 
ATOM   7851  O  O     . GLY   F 3 310 ? 46.982  102.806 -51.421 1.00 53.21  ? 603  GLY   D O     1 
ATOM   7852  N  N     . TRP   F 3 311 ? 45.023  103.130 -52.541 1.00 48.32  ? 604  TRP   D N     1 
ATOM   7853  C  CA    . TRP   F 3 311 ? 44.259  102.105 -51.836 1.00 45.10  ? 604  TRP   D CA    1 
ATOM   7854  C  C     . TRP   F 3 311 ? 43.803  101.026 -52.811 1.00 43.49  ? 604  TRP   D C     1 
ATOM   7855  O  O     . TRP   F 3 311 ? 43.850  101.203 -54.029 1.00 48.41  ? 604  TRP   D O     1 
ATOM   7856  C  CB    . TRP   F 3 311 ? 43.055  102.690 -51.079 1.00 43.23  ? 604  TRP   D CB    1 
ATOM   7857  C  CG    . TRP   F 3 311 ? 43.377  103.664 -49.988 1.00 39.66  ? 604  TRP   D CG    1 
ATOM   7858  C  CD1   . TRP   F 3 311 ? 44.123  104.797 -50.107 1.00 42.63  ? 604  TRP   D CD1   1 
ATOM   7859  C  CD2   . TRP   F 3 311 ? 42.920  103.634 -48.624 1.00 42.49  ? 604  TRP   D CD2   1 
ATOM   7860  N  NE1   . TRP   F 3 311 ? 44.178  105.465 -48.913 1.00 44.17  ? 604  TRP   D NE1   1 
ATOM   7861  C  CE2   . TRP   F 3 311 ? 43.462  104.775 -47.978 1.00 44.46  ? 604  TRP   D CE2   1 
ATOM   7862  C  CE3   . TRP   F 3 311 ? 42.118  102.757 -47.876 1.00 41.01  ? 604  TRP   D CE3   1 
ATOM   7863  C  CZ2   . TRP   F 3 311 ? 43.235  105.060 -46.626 1.00 42.99  ? 604  TRP   D CZ2   1 
ATOM   7864  C  CZ3   . TRP   F 3 311 ? 41.898  103.031 -46.541 1.00 41.86  ? 604  TRP   D CZ3   1 
ATOM   7865  C  CH2   . TRP   F 3 311 ? 42.440  104.173 -45.928 1.00 44.26  ? 604  TRP   D CH2   1 
ATOM   7866  N  N     . LEU   F 3 312 ? 43.339  99.912  -52.236 1.00 44.06  ? 605  LEU   D N     1 
ATOM   7867  C  CA    . LEU   F 3 312 ? 42.703  98.840  -52.988 1.00 44.30  ? 605  LEU   D CA    1 
ATOM   7868  C  C     . LEU   F 3 312 ? 41.387  98.449  -52.307 1.00 43.10  ? 605  LEU   D C     1 
ATOM   7869  O  O     . LEU   F 3 312 ? 41.238  98.579  -51.087 1.00 42.09  ? 605  LEU   D O     1 
ATOM   7870  C  CB    . LEU   F 3 312 ? 43.661  97.641  -53.059 1.00 44.71  ? 605  LEU   D CB    1 
ATOM   7871  C  CG    . LEU   F 3 312 ? 44.927  97.814  -53.906 1.00 44.75  ? 605  LEU   D CG    1 
ATOM   7872  C  CD1   . LEU   F 3 312 ? 45.808  96.579  -53.795 1.00 46.27  ? 605  LEU   D CD1   1 
ATOM   7873  C  CD2   . LEU   F 3 312 ? 44.588  98.071  -55.372 1.00 42.92  ? 605  LEU   D CD2   1 
ATOM   7874  N  N     . LEU   F 3 313 ? 40.443  97.971  -53.128 1.00 39.59  ? 606  LEU   D N     1 
ATOM   7875  C  CA    . LEU   F 3 313 ? 39.232  97.321  -52.656 1.00 39.19  ? 606  LEU   D CA    1 
ATOM   7876  C  C     . LEU   F 3 313 ? 39.536  95.864  -52.317 1.00 39.83  ? 606  LEU   D C     1 
ATOM   7877  O  O     . LEU   F 3 313 ? 40.249  95.199  -53.073 1.00 37.22  ? 606  LEU   D O     1 
ATOM   7878  C  CB    . LEU   F 3 313 ? 38.157  97.390  -53.748 1.00 35.02  ? 606  LEU   D CB    1 
ATOM   7879  C  CG    . LEU   F 3 313 ? 37.647  98.789  -54.098 1.00 36.34  ? 606  LEU   D CG    1 
ATOM   7880  C  CD1   . LEU   F 3 313 ? 36.389  98.700  -54.939 1.00 39.67  ? 606  LEU   D CD1   1 
ATOM   7881  C  CD2   . LEU   F 3 313 ? 37.388  99.644  -52.865 1.00 37.07  ? 606  LEU   D CD2   1 
ATOM   7882  N  N     . VAL   F 3 314 ? 38.958  95.385  -51.198 1.00 37.10  ? 607  VAL   D N     1 
ATOM   7883  C  CA    . VAL   F 3 314 ? 38.951  93.970  -50.845 1.00 35.08  ? 607  VAL   D CA    1 
ATOM   7884  C  C     . VAL   F 3 314 ? 37.500  93.497  -50.784 1.00 34.48  ? 607  VAL   D C     1 
ATOM   7885  O  O     . VAL   F 3 314 ? 36.714  93.998  -49.988 1.00 36.78  ? 607  VAL   D O     1 
ATOM   7886  C  CB    . VAL   F 3 314 ? 39.681  93.726  -49.509 1.00 36.35  ? 607  VAL   D CB    1 
ATOM   7887  C  CG1   . VAL   F 3 314 ? 39.920  92.244  -49.258 1.00 39.47  ? 607  VAL   D CG1   1 
ATOM   7888  C  CG2   . VAL   F 3 314 ? 40.999  94.484  -49.444 1.00 36.47  ? 607  VAL   D CG2   1 
ATOM   7889  N  N     . ALA   F 3 315 ? 37.142  92.547  -51.648 1.00 33.50  ? 608  ALA   D N     1 
ATOM   7890  C  CA    . ALA   F 3 315 ? 35.803  91.996  -51.704 1.00 35.90  ? 608  ALA   D CA    1 
ATOM   7891  C  C     . ALA   F 3 315 ? 35.806  90.552  -51.195 1.00 39.25  ? 608  ALA   D C     1 
ATOM   7892  O  O     . ALA   F 3 315 ? 36.545  89.726  -51.729 1.00 34.12  ? 608  ALA   D O     1 
ATOM   7893  C  CB    . ALA   F 3 315 ? 35.303  92.048  -53.122 1.00 36.99  ? 608  ALA   D CB    1 
ATOM   7894  N  N     . LEU   F 3 316 ? 34.934  90.263  -50.207 1.00 38.92  ? 609  LEU   D N     1 
ATOM   7895  C  CA    . LEU   F 3 316 ? 34.781  88.944  -49.614 1.00 36.51  ? 609  LEU   D CA    1 
ATOM   7896  C  C     . LEU   F 3 316 ? 33.309  88.549  -49.665 1.00 38.49  ? 609  LEU   D C     1 
ATOM   7897  O  O     . LEU   F 3 316 ? 32.472  89.256  -49.102 1.00 37.53  ? 609  LEU   D O     1 
ATOM   7898  C  CB    . LEU   F 3 316 ? 35.254  88.984  -48.159 1.00 37.72  ? 609  LEU   D CB    1 
ATOM   7899  C  CG    . LEU   F 3 316 ? 36.596  89.663  -47.901 1.00 37.25  ? 609  LEU   D CG    1 
ATOM   7900  C  CD1   . LEU   F 3 316 ? 36.407  91.049  -47.289 1.00 36.24  ? 609  LEU   D CD1   1 
ATOM   7901  C  CD2   . LEU   F 3 316 ? 37.458  88.791  -47.012 1.00 35.51  ? 609  LEU   D CD2   1 
ATOM   7902  N  N     . ASP   F 3 317 ? 33.024  87.396  -50.292 1.00 39.44  ? 610  ASP   D N     1 
ATOM   7903  C  CA    . ASP   F 3 317 ? 31.670  86.914  -50.542 1.00 43.71  ? 610  ASP   D CA    1 
ATOM   7904  C  C     . ASP   F 3 317 ? 31.569  85.481  -50.018 1.00 43.65  ? 610  ASP   D C     1 
ATOM   7905  O  O     . ASP   F 3 317 ? 32.273  84.619  -50.536 1.00 51.27  ? 610  ASP   D O     1 
ATOM   7906  C  CB    . ASP   F 3 317 ? 31.345  86.970  -52.050 1.00 44.35  ? 610  ASP   D CB    1 
ATOM   7907  C  CG    . ASP   F 3 317 ? 29.909  86.643  -52.475 1.00 50.73  ? 610  ASP   D CG    1 
ATOM   7908  O  OD1   . ASP   F 3 317 ? 29.335  85.583  -52.055 1.00 49.67  ? 610  ASP   D OD1   1 
ATOM   7909  O  OD2   . ASP   F 3 317 ? 29.371  87.435  -53.284 1.00 52.83  ? 610  ASP   D OD2   1 
ATOM   7910  N  N     . TYR   F 3 318 ? 30.698  85.220  -49.020 1.00 43.18  ? 611  TYR   D N     1 
ATOM   7911  C  CA    . TYR   F 3 318 ? 30.427  83.850  -48.595 1.00 36.78  ? 611  TYR   D CA    1 
ATOM   7912  C  C     . TYR   F 3 318 ? 29.981  82.988  -49.784 1.00 40.06  ? 611  TYR   D C     1 
ATOM   7913  O  O     . TYR   F 3 318 ? 29.045  83.319  -50.531 1.00 45.24  ? 611  TYR   D O     1 
ATOM   7914  C  CB    . TYR   F 3 318 ? 29.405  83.767  -47.464 1.00 36.63  ? 611  TYR   D CB    1 
ATOM   7915  C  CG    . TYR   F 3 318 ? 29.852  84.215  -46.095 1.00 35.26  ? 611  TYR   D CG    1 
ATOM   7916  C  CD1   . TYR   F 3 318 ? 30.781  83.503  -45.355 1.00 39.78  ? 611  TYR   D CD1   1 
ATOM   7917  C  CD2   . TYR   F 3 318 ? 29.300  85.337  -45.498 1.00 34.98  ? 611  TYR   D CD2   1 
ATOM   7918  C  CE1   . TYR   F 3 318 ? 31.181  83.911  -44.085 1.00 34.47  ? 611  TYR   D CE1   1 
ATOM   7919  C  CE2   . TYR   F 3 318 ? 29.673  85.744  -44.225 1.00 34.34  ? 611  TYR   D CE2   1 
ATOM   7920  C  CZ    . TYR   F 3 318 ? 30.618  85.035  -43.507 1.00 34.02  ? 611  TYR   D CZ    1 
ATOM   7921  O  OH    . TYR   F 3 318 ? 30.975  85.479  -42.234 1.00 33.50  ? 611  TYR   D OH    1 
ATOM   7922  N  N     . SER   F 3 319 ? 30.728  81.884  -49.966 1.00 38.04  ? 612  SER   D N     1 
ATOM   7923  C  CA    . SER   F 3 319 ? 30.469  80.904  -51.012 1.00 38.76  ? 612  SER   D CA    1 
ATOM   7924  C  C     . SER   F 3 319 ? 29.241  80.073  -50.641 1.00 37.65  ? 612  SER   D C     1 
ATOM   7925  O  O     . SER   F 3 319 ? 29.174  79.569  -49.526 1.00 41.59  ? 612  SER   D O     1 
ATOM   7926  C  CB    . SER   F 3 319 ? 31.688  80.033  -51.265 1.00 42.15  ? 612  SER   D CB    1 
ATOM   7927  O  OG    . SER   F 3 319 ? 31.323  78.801  -51.910 1.00 48.29  ? 612  SER   D OG    1 
ATOM   7928  N  N     . GLN   F 3 320 ? 28.297  79.973  -51.592 1.00 39.06  ? 613  GLN   D N     1 
ATOM   7929  C  CA    . GLN   F 3 320 ? 27.064  79.206  -51.499 1.00 38.65  ? 613  GLN   D CA    1 
ATOM   7930  C  C     . GLN   F 3 320 ? 26.498  79.329  -50.087 1.00 39.12  ? 613  GLN   D C     1 
ATOM   7931  O  O     . GLN   F 3 320 ? 26.027  78.344  -49.536 1.00 41.11  ? 613  GLN   D O     1 
ATOM   7932  C  CB    . GLN   F 3 320 ? 27.276  77.733  -51.887 1.00 42.12  ? 613  GLN   D CB    1 
ATOM   7933  C  CG    . GLN   F 3 320 ? 27.781  77.465  -53.307 1.00 39.61  ? 613  GLN   D CG    1 
ATOM   7934  C  CD    . GLN   F 3 320 ? 28.159  76.006  -53.477 1.00 46.38  ? 613  GLN   D CD    1 
ATOM   7935  O  OE1   . GLN   F 3 320 ? 27.338  75.134  -53.792 1.00 47.83  ? 613  GLN   D OE1   1 
ATOM   7936  N  NE2   . GLN   F 3 320 ? 29.427  75.711  -53.232 1.00 42.20  ? 613  GLN   D NE2   1 
ATOM   7937  N  N     . GLU   F 3 321 ? 26.497  80.559  -49.559 1.00 37.62  ? 614  GLU   D N     1 
ATOM   7938  C  CA    . GLU   F 3 321 ? 26.200  80.882  -48.176 1.00 44.89  ? 614  GLU   D CA    1 
ATOM   7939  C  C     . GLU   F 3 321 ? 24.911  80.223  -47.664 1.00 44.57  ? 614  GLU   D C     1 
ATOM   7940  O  O     . GLU   F 3 321 ? 24.880  79.590  -46.599 1.00 42.46  ? 614  GLU   D O     1 
ATOM   7941  C  CB    . GLU   F 3 321 ? 26.021  82.400  -48.051 1.00 50.69  ? 614  GLU   D CB    1 
ATOM   7942  C  CG    . GLU   F 3 321 ? 25.844  82.868  -46.609 1.00 56.47  ? 614  GLU   D CG    1 
ATOM   7943  C  CD    . GLU   F 3 321 ? 25.153  84.213  -46.376 1.00 72.26  ? 614  GLU   D CD    1 
ATOM   7944  O  OE1   . GLU   F 3 321 ? 24.122  84.486  -47.093 1.00 68.86  ? 614  GLU   D OE1   1 
ATOM   7945  O  OE2   . GLU   F 3 321 ? 25.610  84.978  -45.442 1.00 71.18  ? 614  GLU   D OE2   1 
ATOM   7946  N  N     . GLY   F 3 322 ? 23.826  80.421  -48.414 1.00 40.86  ? 615  GLY   D N     1 
ATOM   7947  C  CA    . GLY   F 3 322 ? 22.505  80.030  -47.956 1.00 40.53  ? 615  GLY   D CA    1 
ATOM   7948  C  C     . GLY   F 3 322 ? 22.339  78.521  -47.891 1.00 39.95  ? 615  GLY   D C     1 
ATOM   7949  O  O     . GLY   F 3 322 ? 21.603  78.017  -47.046 1.00 40.63  ? 615  GLY   D O     1 
ATOM   7950  N  N     . LEU   F 3 323 ? 23.012  77.835  -48.823 1.00 40.85  ? 616  LEU   D N     1 
ATOM   7951  C  CA    . LEU   F 3 323 ? 23.026  76.387  -48.891 1.00 40.62  ? 616  LEU   D CA    1 
ATOM   7952  C  C     . LEU   F 3 323 ? 23.871  75.804  -47.758 1.00 35.10  ? 616  LEU   D C     1 
ATOM   7953  O  O     . LEU   F 3 323 ? 23.537  74.755  -47.251 1.00 34.14  ? 616  LEU   D O     1 
ATOM   7954  C  CB    . LEU   F 3 323 ? 23.570  75.962  -50.258 1.00 43.91  ? 616  LEU   D CB    1 
ATOM   7955  C  CG    . LEU   F 3 323 ? 22.752  76.394  -51.471 1.00 50.56  ? 616  LEU   D CG    1 
ATOM   7956  C  CD1   . LEU   F 3 323 ? 23.494  76.053  -52.761 1.00 56.97  ? 616  LEU   D CD1   1 
ATOM   7957  C  CD2   . LEU   F 3 323 ? 21.357  75.764  -51.471 1.00 50.11  ? 616  LEU   D CD2   1 
ATOM   7958  N  N     . ARG   F 3 324 ? 24.969  76.463  -47.367 1.00 36.62  ? 617  ARG   D N     1 
ATOM   7959  C  CA    . ARG   F 3 324 ? 25.737  76.026  -46.208 1.00 33.89  ? 617  ARG   D CA    1 
ATOM   7960  C  C     . ARG   F 3 324 ? 24.909  76.183  -44.939 1.00 33.24  ? 617  ARG   D C     1 
ATOM   7961  O  O     . ARG   F 3 324 ? 24.987  75.356  -44.047 1.00 34.94  ? 617  ARG   D O     1 
ATOM   7962  C  CB    . ARG   F 3 324 ? 27.040  76.803  -46.028 1.00 30.74  ? 617  ARG   D CB    1 
ATOM   7963  C  CG    . ARG   F 3 324 ? 28.035  76.567  -47.145 1.00 31.98  ? 617  ARG   D CG    1 
ATOM   7964  C  CD    . ARG   F 3 324 ? 29.403  77.166  -46.869 1.00 34.20  ? 617  ARG   D CD    1 
ATOM   7965  N  NE    . ARG   F 3 324 ? 30.210  77.131  -48.093 1.00 34.31  ? 617  ARG   D NE    1 
ATOM   7966  C  CZ    . ARG   F 3 324 ? 31.239  76.330  -48.316 1.00 32.38  ? 617  ARG   D CZ    1 
ATOM   7967  N  NH1   . ARG   F 3 324 ? 31.815  75.664  -47.326 1.00 28.96  ? 617  ARG   D NH1   1 
ATOM   7968  N  NH2   . ARG   F 3 324 ? 31.707  76.237  -49.544 1.00 33.53  ? 617  ARG   D NH2   1 
ATOM   7969  N  N     . VAL   F 3 325 ? 24.144  77.269  -44.852 1.00 34.97  ? 618  VAL   D N     1 
ATOM   7970  C  CA    . VAL   F 3 325 ? 23.314  77.521  -43.685 1.00 32.41  ? 618  VAL   D CA    1 
ATOM   7971  C  C     . VAL   F 3 325 ? 22.216  76.458  -43.604 1.00 30.41  ? 618  VAL   D C     1 
ATOM   7972  O  O     . VAL   F 3 325 ? 21.912  75.958  -42.525 1.00 30.96  ? 618  VAL   D O     1 
ATOM   7973  C  CB    . VAL   F 3 325 ? 22.762  78.955  -43.717 1.00 30.57  ? 618  VAL   D CB    1 
ATOM   7974  C  CG1   . VAL   F 3 325 ? 21.648  79.172  -42.714 1.00 29.74  ? 618  VAL   D CG1   1 
ATOM   7975  C  CG2   . VAL   F 3 325 ? 23.881  79.960  -43.481 1.00 33.81  ? 618  VAL   D CG2   1 
ATOM   7976  N  N     . LEU   F 3 326 ? 21.665  76.072  -44.753 1.00 27.47  ? 619  LEU   D N     1 
ATOM   7977  C  CA    . LEU   F 3 326 ? 20.641  75.050  -44.790 1.00 28.25  ? 619  LEU   D CA    1 
ATOM   7978  C  C     . LEU   F 3 326 ? 21.204  73.705  -44.347 1.00 28.92  ? 619  LEU   D C     1 
ATOM   7979  O  O     . LEU   F 3 326 ? 20.534  72.953  -43.647 1.00 33.99  ? 619  LEU   D O     1 
ATOM   7980  C  CB    . LEU   F 3 326 ? 20.116  74.956  -46.222 1.00 31.48  ? 619  LEU   D CB    1 
ATOM   7981  C  CG    . LEU   F 3 326 ? 19.113  73.839  -46.489 1.00 31.54  ? 619  LEU   D CG    1 
ATOM   7982  C  CD1   . LEU   F 3 326 ? 17.833  74.055  -45.695 1.00 33.44  ? 619  LEU   D CD1   1 
ATOM   7983  C  CD2   . LEU   F 3 326 ? 18.821  73.749  -47.978 1.00 36.37  ? 619  LEU   D CD2   1 
ATOM   7984  N  N     . ALA   F 3 327 ? 22.401  73.372  -44.822 1.00 29.07  ? 620  ALA   D N     1 
ATOM   7985  C  CA    . ALA   F 3 327 ? 23.045  72.124  -44.446 1.00 31.69  ? 620  ALA   D CA    1 
ATOM   7986  C  C     . ALA   F 3 327 ? 23.159  72.025  -42.923 1.00 30.28  ? 620  ALA   D C     1 
ATOM   7987  O  O     . ALA   F 3 327 ? 22.876  70.979  -42.339 1.00 36.40  ? 620  ALA   D O     1 
ATOM   7988  C  CB    . ALA   F 3 327 ? 24.401  72.039  -45.112 1.00 31.88  ? 620  ALA   D CB    1 
ATOM   7989  N  N     . HIS   F 3 328 ? 23.542  73.123  -42.271 1.00 32.67  ? 621  HIS   D N     1 
ATOM   7990  C  CA    . HIS   F 3 328 ? 23.611  73.173  -40.811 1.00 32.76  ? 621  HIS   D CA    1 
ATOM   7991  C  C     . HIS   F 3 328 ? 22.226  73.058  -40.172 1.00 31.03  ? 621  HIS   D C     1 
ATOM   7992  O  O     . HIS   F 3 328 ? 22.022  72.287  -39.243 1.00 31.00  ? 621  HIS   D O     1 
ATOM   7993  C  CB    . HIS   F 3 328 ? 24.273  74.465  -40.333 1.00 34.30  ? 621  HIS   D CB    1 
ATOM   7994  C  CG    . HIS   F 3 328 ? 24.334  74.573  -38.840 1.00 35.77  ? 621  HIS   D CG    1 
ATOM   7995  N  ND1   . HIS   F 3 328 ? 25.341  74.032  -38.083 1.00 36.55  ? 621  HIS   D ND1   1 
ATOM   7996  C  CD2   . HIS   F 3 328 ? 23.457  75.156  -37.976 1.00 36.23  ? 621  HIS   D CD2   1 
ATOM   7997  C  CE1   . HIS   F 3 328 ? 25.093  74.258  -36.798 1.00 38.53  ? 621  HIS   D CE1   1 
ATOM   7998  N  NE2   . HIS   F 3 328 ? 23.928  74.960  -36.709 1.00 36.83  ? 621  HIS   D NE2   1 
ATOM   7999  N  N     . LEU   F 3 329 ? 21.266  73.858  -40.632 1.00 29.64  ? 622  LEU   D N     1 
ATOM   8000  C  CA    . LEU   F 3 329 ? 19.947  73.836  -40.018 1.00 29.59  ? 622  LEU   D CA    1 
ATOM   8001  C  C     . LEU   F 3 329 ? 19.310  72.454  -40.134 1.00 30.09  ? 622  LEU   D C     1 
ATOM   8002  O  O     . LEU   F 3 329 ? 18.651  71.988  -39.205 1.00 34.09  ? 622  LEU   D O     1 
ATOM   8003  C  CB    . LEU   F 3 329 ? 19.062  74.899  -40.673 1.00 28.38  ? 622  LEU   D CB    1 
ATOM   8004  C  CG    . LEU   F 3 329 ? 19.457  76.342  -40.370 1.00 28.57  ? 622  LEU   D CG    1 
ATOM   8005  C  CD1   . LEU   F 3 329 ? 18.489  77.311  -41.032 1.00 28.99  ? 622  LEU   D CD1   1 
ATOM   8006  C  CD2   . LEU   F 3 329 ? 19.544  76.595  -38.865 1.00 25.37  ? 622  LEU   D CD2   1 
ATOM   8007  N  N     . SER   F 3 330 ? 19.472  71.825  -41.297 1.00 28.81  ? 623  SER   D N     1 
ATOM   8008  C  CA    . SER   F 3 330 ? 18.789  70.577  -41.600 1.00 29.14  ? 623  SER   D CA    1 
ATOM   8009  C  C     . SER   F 3 330 ? 19.582  69.357  -41.124 1.00 28.66  ? 623  SER   D C     1 
ATOM   8010  O  O     . SER   F 3 330 ? 19.013  68.279  -40.962 1.00 29.25  ? 623  SER   D O     1 
ATOM   8011  C  CB    . SER   F 3 330 ? 18.560  70.488  -43.086 1.00 29.47  ? 623  SER   D CB    1 
ATOM   8012  O  OG    . SER   F 3 330 ? 19.804  70.308  -43.764 1.00 27.67  ? 623  SER   D OG    1 
ATOM   8013  N  N     . GLY   F 3 331 ? 20.904  69.510  -40.991 1.00 30.58  ? 624  GLY   D N     1 
ATOM   8014  C  CA    . GLY   F 3 331 ? 21.819  68.409  -40.728 1.00 30.63  ? 624  GLY   D CA    1 
ATOM   8015  C  C     . GLY   F 3 331 ? 21.927  67.415  -41.894 1.00 34.45  ? 624  GLY   D C     1 
ATOM   8016  O  O     . GLY   F 3 331 ? 22.403  66.296  -41.717 1.00 38.10  ? 624  GLY   D O     1 
ATOM   8017  N  N     . ASP   F 3 332 ? 21.536  67.826  -43.100 1.00 36.36  ? 625  ASP   D N     1 
ATOM   8018  C  CA    . ASP   F 3 332 ? 21.491  66.906  -44.222 1.00 36.59  ? 625  ASP   D CA    1 
ATOM   8019  C  C     . ASP   F 3 332 ? 22.908  66.552  -44.649 1.00 37.02  ? 625  ASP   D C     1 
ATOM   8020  O  O     . ASP   F 3 332 ? 23.624  67.394  -45.186 1.00 37.31  ? 625  ASP   D O     1 
ATOM   8021  C  CB    . ASP   F 3 332 ? 20.701  67.464  -45.407 1.00 35.89  ? 625  ASP   D CB    1 
ATOM   8022  C  CG    . ASP   F 3 332 ? 20.526  66.406  -46.491 1.00 37.86  ? 625  ASP   D CG    1 
ATOM   8023  O  OD1   . ASP   F 3 332 ? 21.530  66.092  -47.166 1.00 36.21  ? 625  ASP   D OD1   1 
ATOM   8024  O  OD2   . ASP   F 3 332 ? 19.406  65.867  -46.609 1.00 35.04  ? 625  ASP   D OD2   1 
ATOM   8025  N  N     . GLU   F 3 333 ? 23.303  65.285  -44.479 1.00 39.65  ? 626  GLU   D N     1 
ATOM   8026  C  CA    . GLU   F 3 333 ? 24.721  64.975  -44.611 1.00 41.44  ? 626  GLU   D CA    1 
ATOM   8027  C  C     . GLU   F 3 333 ? 25.122  64.825  -46.075 1.00 38.48  ? 626  GLU   D C     1 
ATOM   8028  O  O     . GLU   F 3 333 ? 26.316  64.915  -46.384 1.00 38.26  ? 626  GLU   D O     1 
ATOM   8029  C  CB    . GLU   F 3 333 ? 25.162  63.810  -43.724 1.00 48.48  ? 626  GLU   D CB    1 
ATOM   8030  C  CG    . GLU   F 3 333 ? 24.162  62.699  -43.611 1.00 55.78  ? 626  GLU   D CG    1 
ATOM   8031  C  CD    . GLU   F 3 333 ? 23.124  62.738  -42.500 1.00 49.93  ? 626  GLU   D CD    1 
ATOM   8032  O  OE1   . GLU   F 3 333 ? 23.466  62.362  -41.380 1.00 56.54  ? 626  GLU   D OE1   1 
ATOM   8033  O  OE2   . GLU   F 3 333 ? 21.951  63.023  -42.795 1.00 50.15  ? 626  GLU   D OE2   1 
ATOM   8034  N  N     . ASN   F 3 334 ? 24.143  64.690  -46.984 1.00 33.71  ? 627  ASN   D N     1 
ATOM   8035  C  CA    . ASN   F 3 334 ? 24.459  64.698  -48.405 1.00 36.72  ? 627  ASN   D CA    1 
ATOM   8036  C  C     . ASN   F 3 334 ? 24.809  66.129  -48.795 1.00 39.50  ? 627  ASN   D C     1 
ATOM   8037  O  O     . ASN   F 3 334 ? 25.722  66.359  -49.579 1.00 37.18  ? 627  ASN   D O     1 
ATOM   8038  C  CB    . ASN   F 3 334 ? 23.344  64.106  -49.289 1.00 37.98  ? 627  ASN   D CB    1 
ATOM   8039  C  CG    . ASN   F 3 334 ? 23.184  62.601  -49.116 1.00 44.77  ? 627  ASN   D CG    1 
ATOM   8040  O  OD1   . ASN   F 3 334 ? 22.622  62.138  -48.119 1.00 42.45  ? 627  ASN   D OD1   1 
ATOM   8041  N  ND2   . ASN   F 3 334 ? 23.668  61.825  -50.081 1.00 39.57  ? 627  ASN   D ND2   1 
ATOM   8042  N  N     . LEU   F 3 335 ? 24.096  67.097  -48.199 1.00 41.65  ? 628  LEU   D N     1 
ATOM   8043  C  CA    . LEU   F 3 335 ? 24.360  68.498  -48.474 1.00 36.98  ? 628  LEU   D CA    1 
ATOM   8044  C  C     . LEU   F 3 335 ? 25.672  68.913  -47.803 1.00 35.83  ? 628  LEU   D C     1 
ATOM   8045  O  O     . LEU   F 3 335 ? 26.485  69.604  -48.410 1.00 35.14  ? 628  LEU   D O     1 
ATOM   8046  C  CB    . LEU   F 3 335 ? 23.154  69.322  -48.014 1.00 38.99  ? 628  LEU   D CB    1 
ATOM   8047  C  CG    . LEU   F 3 335 ? 23.128  70.756  -48.535 1.00 43.07  ? 628  LEU   D CG    1 
ATOM   8048  C  CD1   . LEU   F 3 335 ? 23.127  70.760  -50.058 1.00 45.04  ? 628  LEU   D CD1   1 
ATOM   8049  C  CD2   . LEU   F 3 335 ? 21.936  71.524  -47.989 1.00 39.08  ? 628  LEU   D CD2   1 
ATOM   8050  N  N     . ILE   F 3 336 ? 25.929  68.424  -46.584 1.00 37.89  ? 629  ILE   D N     1 
ATOM   8051  C  CA    . ILE   F 3 336 ? 27.207  68.660  -45.919 1.00 38.09  ? 629  ILE   D CA    1 
ATOM   8052  C  C     . ILE   F 3 336 ? 28.346  68.116  -46.786 1.00 39.26  ? 629  ILE   D C     1 
ATOM   8053  O  O     . ILE   F 3 336 ? 29.403  68.738  -46.882 1.00 44.79  ? 629  ILE   D O     1 
ATOM   8054  C  CB    . ILE   F 3 336 ? 27.191  68.059  -44.497 1.00 38.36  ? 629  ILE   D CB    1 
ATOM   8055  C  CG1   . ILE   F 3 336 ? 26.207  68.798  -43.582 1.00 38.83  ? 629  ILE   D CG1   1 
ATOM   8056  C  CG2   . ILE   F 3 336 ? 28.573  68.019  -43.865 1.00 36.57  ? 629  ILE   D CG2   1 
ATOM   8057  C  CD1   . ILE   F 3 336 ? 25.933  68.057  -42.277 1.00 38.43  ? 629  ILE   D CD1   1 
ATOM   8058  N  N     . ARG   F 3 337 ? 28.102  66.989  -47.467 1.00 39.88  ? 630  ARG   D N     1 
ATOM   8059  C  CA    . ARG   F 3 337 ? 29.115  66.322  -48.277 1.00 40.11  ? 630  ARG   D CA    1 
ATOM   8060  C  C     . ARG   F 3 337 ? 29.497  67.145  -49.509 1.00 37.54  ? 630  ARG   D C     1 
ATOM   8061  O  O     . ARG   F 3 337 ? 30.652  67.147  -49.933 1.00 38.91  ? 630  ARG   D O     1 
ATOM   8062  C  CB    . ARG   F 3 337 ? 28.597  64.947  -48.720 1.00 49.78  ? 630  ARG   D CB    1 
ATOM   8063  C  CG    . ARG   F 3 337 ? 29.569  64.145  -49.575 1.00 54.65  ? 630  ARG   D CG    1 
ATOM   8064  C  CD    . ARG   F 3 337 ? 30.735  63.726  -48.699 1.00 62.16  ? 630  ARG   D CD    1 
ATOM   8065  N  NE    . ARG   F 3 337 ? 31.851  63.099  -49.394 1.00 64.11  ? 630  ARG   D NE    1 
ATOM   8066  C  CZ    . ARG   F 3 337 ? 33.020  62.852  -48.817 1.00 64.17  ? 630  ARG   D CZ    1 
ATOM   8067  N  NH1   . ARG   F 3 337 ? 33.223  63.240  -47.567 1.00 62.72  ? 630  ARG   D NH1   1 
ATOM   8068  N  NH2   . ARG   F 3 337 ? 33.965  62.219  -49.490 1.00 66.56  ? 630  ARG   D NH2   1 
ATOM   8069  N  N     . VAL   F 3 338 ? 28.514  67.782  -50.145 1.00 36.80  ? 631  VAL   D N     1 
ATOM   8070  C  CA    . VAL   F 3 338 ? 28.780  68.685  -51.256 1.00 38.40  ? 631  VAL   D CA    1 
ATOM   8071  C  C     . VAL   F 3 338 ? 29.969  69.595  -50.941 1.00 37.53  ? 631  VAL   D C     1 
ATOM   8072  O  O     . VAL   F 3 338 ? 30.880  69.713  -51.755 1.00 41.32  ? 631  VAL   D O     1 
ATOM   8073  C  CB    . VAL   F 3 338 ? 27.531  69.511  -51.618 1.00 37.86  ? 631  VAL   D CB    1 
ATOM   8074  C  CG1   . VAL   F 3 338 ? 27.867  70.686  -52.515 1.00 37.23  ? 631  VAL   D CG1   1 
ATOM   8075  C  CG2   . VAL   F 3 338 ? 26.463  68.651  -52.266 1.00 40.05  ? 631  VAL   D CG2   1 
ATOM   8076  N  N     . PHE   F 3 339 ? 29.955  70.226  -49.758 1.00 40.67  ? 632  PHE   D N     1 
ATOM   8077  C  CA    . PHE   F 3 339 ? 30.953  71.218  -49.373 1.00 38.17  ? 632  PHE   D CA    1 
ATOM   8078  C  C     . PHE   F 3 339 ? 32.281  70.559  -49.009 1.00 41.97  ? 632  PHE   D C     1 
ATOM   8079  O  O     . PHE   F 3 339 ? 33.330  71.017  -49.463 1.00 46.57  ? 632  PHE   D O     1 
ATOM   8080  C  CB    . PHE   F 3 339 ? 30.386  72.101  -48.257 1.00 36.05  ? 632  PHE   D CB    1 
ATOM   8081  C  CG    . PHE   F 3 339 ? 29.125  72.786  -48.719 1.00 36.52  ? 632  PHE   D CG    1 
ATOM   8082  C  CD1   . PHE   F 3 339 ? 29.172  73.735  -49.729 1.00 40.20  ? 632  PHE   D CD1   1 
ATOM   8083  C  CD2   . PHE   F 3 339 ? 27.894  72.419  -48.225 1.00 33.62  ? 632  PHE   D CD2   1 
ATOM   8084  C  CE1   . PHE   F 3 339 ? 28.013  74.340  -50.189 1.00 39.08  ? 632  PHE   D CE1   1 
ATOM   8085  C  CE2   . PHE   F 3 339 ? 26.736  73.008  -48.699 1.00 35.89  ? 632  PHE   D CE2   1 
ATOM   8086  C  CZ    . PHE   F 3 339 ? 26.795  73.954  -49.689 1.00 37.98  ? 632  PHE   D CZ    1 
ATOM   8087  N  N     . GLN   F 3 340 ? 32.238  69.466  -48.239 1.00 41.28  ? 633  GLN   D N     1 
ATOM   8088  C  CA    . GLN   F 3 340 ? 33.446  68.732  -47.884 1.00 45.66  ? 633  GLN   D CA    1 
ATOM   8089  C  C     . GLN   F 3 340 ? 34.205  68.261  -49.127 1.00 46.10  ? 633  GLN   D C     1 
ATOM   8090  O  O     . GLN   F 3 340 ? 35.427  68.163  -49.067 1.00 53.42  ? 633  GLN   D O     1 
ATOM   8091  C  CB    . GLN   F 3 340 ? 33.098  67.578  -46.940 1.00 46.99  ? 633  GLN   D CB    1 
ATOM   8092  C  CG    . GLN   F 3 340 ? 32.757  68.076  -45.533 1.00 51.43  ? 633  GLN   D CG    1 
ATOM   8093  C  CD    . GLN   F 3 340 ? 32.175  67.057  -44.578 1.00 56.68  ? 633  GLN   D CD    1 
ATOM   8094  O  OE1   . GLN   F 3 340 ? 31.923  67.386  -43.415 1.00 50.94  ? 633  GLN   D OE1   1 
ATOM   8095  N  NE2   . GLN   F 3 340 ? 31.972  65.826  -45.050 1.00 55.53  ? 633  GLN   D NE2   1 
ATOM   8096  N  N     . GLU   F 3 341 ? 33.503  67.998  -50.244 1.00 42.18  ? 634  GLU   D N     1 
ATOM   8097  C  CA    . GLU   F 3 341 ? 34.142  67.611  -51.498 1.00 45.26  ? 634  GLU   D CA    1 
ATOM   8098  C  C     . GLU   F 3 341 ? 34.507  68.802  -52.384 1.00 44.37  ? 634  GLU   D C     1 
ATOM   8099  O  O     . GLU   F 3 341 ? 35.044  68.601  -53.468 1.00 42.83  ? 634  GLU   D O     1 
ATOM   8100  C  CB    . GLU   F 3 341 ? 33.217  66.752  -52.358 1.00 48.57  ? 634  GLU   D CB    1 
ATOM   8101  C  CG    . GLU   F 3 341 ? 32.992  65.353  -51.813 1.00 56.95  ? 634  GLU   D CG    1 
ATOM   8102  C  CD    . GLU   F 3 341 ? 32.416  64.435  -52.875 1.00 64.36  ? 634  GLU   D CD    1 
ATOM   8103  O  OE1   . GLU   F 3 341 ? 31.168  64.256  -52.889 1.00 64.46  ? 634  GLU   D OE1   1 
ATOM   8104  O  OE2   . GLU   F 3 341 ? 33.223  63.925  -53.707 1.00 75.34  ? 634  GLU   D OE2   1 
ATOM   8105  N  N     . GLY   F 3 342 ? 34.182  70.031  -51.961 1.00 44.22  ? 635  GLY   D N     1 
ATOM   8106  C  CA    . GLY   F 3 342 ? 34.498  71.213  -52.744 1.00 40.19  ? 635  GLY   D CA    1 
ATOM   8107  C  C     . GLY   F 3 342 ? 33.688  71.283  -54.035 1.00 37.98  ? 635  GLY   D C     1 
ATOM   8108  O  O     . GLY   F 3 342 ? 34.127  71.900  -54.993 1.00 43.24  ? 635  GLY   D O     1 
ATOM   8109  N  N     . ARG   F 3 343 ? 32.481  70.704  -54.043 1.00 39.43  ? 636  ARG   D N     1 
ATOM   8110  C  CA    . ARG   F 3 343 ? 31.573  70.844  -55.173 1.00 37.49  ? 636  ARG   D CA    1 
ATOM   8111  C  C     . ARG   F 3 343 ? 30.793  72.160  -55.097 1.00 38.51  ? 636  ARG   D C     1 
ATOM   8112  O  O     . ARG   F 3 343 ? 30.566  72.737  -54.030 1.00 38.70  ? 636  ARG   D O     1 
ATOM   8113  C  CB    . ARG   F 3 343 ? 30.594  69.670  -55.210 1.00 39.72  ? 636  ARG   D CB    1 
ATOM   8114  C  CG    . ARG   F 3 343 ? 31.227  68.339  -55.625 1.00 40.90  ? 636  ARG   D CG    1 
ATOM   8115  C  CD    . ARG   F 3 343 ? 30.303  67.169  -55.323 1.00 40.18  ? 636  ARG   D CD    1 
ATOM   8116  N  NE    . ARG   F 3 343 ? 29.008  67.282  -55.991 1.00 39.43  ? 636  ARG   D NE    1 
ATOM   8117  C  CZ    . ARG   F 3 343 ? 27.908  66.642  -55.620 1.00 39.73  ? 636  ARG   D CZ    1 
ATOM   8118  N  NH1   . ARG   F 3 343 ? 26.745  66.898  -56.203 1.00 37.19  ? 636  ARG   D NH1   1 
ATOM   8119  N  NH2   . ARG   F 3 343 ? 27.974  65.763  -54.642 1.00 43.65  ? 636  ARG   D NH2   1 
ATOM   8120  N  N     . ASP   F 3 344 ? 30.343  72.591  -56.271 1.00 35.83  ? 637  ASP   D N     1 
ATOM   8121  C  CA    . ASP   F 3 344 ? 29.538  73.784  -56.441 1.00 35.95  ? 637  ASP   D CA    1 
ATOM   8122  C  C     . ASP   F 3 344 ? 28.298  73.385  -57.237 1.00 32.65  ? 637  ASP   D C     1 
ATOM   8123  O  O     . ASP   F 3 344 ? 28.398  73.110  -58.437 1.00 37.28  ? 637  ASP   D O     1 
ATOM   8124  C  CB    . ASP   F 3 344 ? 30.378  74.881  -57.121 1.00 37.80  ? 637  ASP   D CB    1 
ATOM   8125  C  CG    . ASP   F 3 344 ? 29.664  76.217  -57.269 1.00 42.18  ? 637  ASP   D CG    1 
ATOM   8126  O  OD1   . ASP   F 3 344 ? 28.465  76.218  -57.602 1.00 43.73  ? 637  ASP   D OD1   1 
ATOM   8127  O  OD2   . ASP   F 3 344 ? 30.306  77.244  -57.067 1.00 50.86  ? 637  ASP   D OD2   1 
ATOM   8128  N  N     . ILE   F 3 345 ? 27.131  73.383  -56.585 1.00 36.34  ? 638  ILE   D N     1 
ATOM   8129  C  CA    . ILE   F 3 345 ? 25.905  72.907  -57.216 1.00 37.49  ? 638  ILE   D CA    1 
ATOM   8130  C  C     . ILE   F 3 345 ? 25.339  73.951  -58.176 1.00 33.58  ? 638  ILE   D C     1 
ATOM   8131  O  O     . ILE   F 3 345 ? 24.556  73.631  -59.069 1.00 31.19  ? 638  ILE   D O     1 
ATOM   8132  C  CB    . ILE   F 3 345 ? 24.860  72.469  -56.167 1.00 46.02  ? 638  ILE   D CB    1 
ATOM   8133  C  CG1   . ILE   F 3 345 ? 24.119  73.647  -55.541 1.00 54.73  ? 638  ILE   D CG1   1 
ATOM   8134  C  CG2   . ILE   F 3 345 ? 25.499  71.590  -55.101 1.00 46.42  ? 638  ILE   D CG2   1 
ATOM   8135  C  CD1   . ILE   F 3 345 ? 22.896  73.235  -54.747 1.00 63.31  ? 638  ILE   D CD1   1 
ATOM   8136  N  N     . HIS   F 3 346 ? 25.708  75.221  -57.999 1.00 33.79  ? 639  HIS   D N     1 
ATOM   8137  C  CA    . HIS   F 3 346 ? 25.312  76.212  -58.989 1.00 32.75  ? 639  HIS   D CA    1 
ATOM   8138  C  C     . HIS   F 3 346 ? 25.998  75.899  -60.321 1.00 34.94  ? 639  HIS   D C     1 
ATOM   8139  O  O     . HIS   F 3 346 ? 25.333  75.883  -61.355 1.00 34.16  ? 639  HIS   D O     1 
ATOM   8140  C  CB    . HIS   F 3 346 ? 25.608  77.639  -58.499 1.00 32.03  ? 639  HIS   D CB    1 
ATOM   8141  C  CG    . HIS   F 3 346 ? 24.883  78.043  -57.256 1.00 31.29  ? 639  HIS   D CG    1 
ATOM   8142  N  ND1   . HIS   F 3 346 ? 23.598  77.637  -56.950 1.00 29.57  ? 639  HIS   D ND1   1 
ATOM   8143  C  CD2   . HIS   F 3 346 ? 25.337  78.811  -56.220 1.00 28.78  ? 639  HIS   D CD2   1 
ATOM   8144  C  CE1   . HIS   F 3 346 ? 23.259  78.179  -55.784 1.00 27.97  ? 639  HIS   D CE1   1 
ATOM   8145  N  NE2   . HIS   F 3 346 ? 24.321  78.915  -55.314 1.00 26.72  ? 639  HIS   D NE2   1 
ATOM   8146  N  N     . THR   F 3 347 ? 27.321  75.629  -60.284 1.00 37.49  ? 640  THR   D N     1 
ATOM   8147  C  CA    . THR   F 3 347 ? 28.063  75.221  -61.474 1.00 40.37  ? 640  THR   D CA    1 
ATOM   8148  C  C     . THR   F 3 347 ? 27.499  73.907  -62.039 1.00 42.08  ? 640  THR   D C     1 
ATOM   8149  O  O     . THR   F 3 347 ? 27.289  73.767  -63.249 1.00 41.27  ? 640  THR   D O     1 
ATOM   8150  C  CB    . THR   F 3 347 ? 29.560  75.069  -61.175 1.00 44.56  ? 640  THR   D CB    1 
ATOM   8151  O  OG1   . THR   F 3 347 ? 30.036  76.221  -60.485 1.00 43.56  ? 640  THR   D OG1   1 
ATOM   8152  C  CG2   . THR   F 3 347 ? 30.386  74.872  -62.427 1.00 46.36  ? 640  THR   D CG2   1 
ATOM   8153  N  N     . GLU   F 3 348 ? 27.245  72.927  -61.164 1.00 39.30  ? 641  GLU   D N     1 
ATOM   8154  C  CA    . GLU   F 3 348 ? 26.748  71.645  -61.637 1.00 38.65  ? 641  GLU   D CA    1 
ATOM   8155  C  C     . GLU   F 3 348 ? 25.420  71.829  -62.359 1.00 37.03  ? 641  GLU   D C     1 
ATOM   8156  O  O     . GLU   F 3 348 ? 25.224  71.262  -63.429 1.00 40.42  ? 641  GLU   D O     1 
ATOM   8157  C  CB    . GLU   F 3 348 ? 26.607  70.661  -60.481 1.00 42.26  ? 641  GLU   D CB    1 
ATOM   8158  C  CG    . GLU   F 3 348 ? 27.955  70.120  -60.030 1.00 44.21  ? 641  GLU   D CG    1 
ATOM   8159  C  CD    . GLU   F 3 348 ? 27.926  69.192  -58.834 1.00 40.51  ? 641  GLU   D CD    1 
ATOM   8160  O  OE1   . GLU   F 3 348 ? 26.826  68.754  -58.440 1.00 40.06  ? 641  GLU   D OE1   1 
ATOM   8161  O  OE2   . GLU   F 3 348 ? 29.003  68.957  -58.275 1.00 38.84  ? 641  GLU   D OE2   1 
ATOM   8162  N  N     . THR   F 3 349 ? 24.512  72.636  -61.798 1.00 34.07  ? 642  THR   D N     1 
ATOM   8163  C  CA    . THR   F 3 349 ? 23.224  72.835  -62.452 1.00 34.42  ? 642  THR   D CA    1 
ATOM   8164  C  C     . THR   F 3 349 ? 23.402  73.582  -63.780 1.00 34.23  ? 642  THR   D C     1 
ATOM   8165  O  O     . THR   F 3 349 ? 22.781  73.240  -64.780 1.00 34.92  ? 642  THR   D O     1 
ATOM   8166  C  CB    . THR   F 3 349 ? 22.252  73.561  -61.523 1.00 34.18  ? 642  THR   D CB    1 
ATOM   8167  O  OG1   . THR   F 3 349 ? 22.046  72.733  -60.381 1.00 33.67  ? 642  THR   D OG1   1 
ATOM   8168  C  CG2   . THR   F 3 349 ? 20.924  73.876  -62.169 1.00 33.45  ? 642  THR   D CG2   1 
ATOM   8169  N  N     . ALA   F 3 350 ? 24.247  74.611  -63.791 1.00 34.56  ? 643  ALA   D N     1 
ATOM   8170  C  CA    . ALA   F 3 350 ? 24.438  75.429  -64.986 1.00 39.52  ? 643  ALA   D CA    1 
ATOM   8171  C  C     . ALA   F 3 350 ? 24.987  74.589  -66.148 1.00 38.88  ? 643  ALA   D C     1 
ATOM   8172  O  O     . ALA   F 3 350 ? 24.502  74.685  -67.275 1.00 40.10  ? 643  ALA   D O     1 
ATOM   8173  C  CB    . ALA   F 3 350 ? 25.349  76.597  -64.657 1.00 38.27  ? 643  ALA   D CB    1 
ATOM   8174  N  N     . SER   F 3 351 ? 25.997  73.761  -65.860 1.00 38.78  ? 644  SER   D N     1 
ATOM   8175  C  CA    . SER   F 3 351 ? 26.588  72.858  -66.841 1.00 45.96  ? 644  SER   D CA    1 
ATOM   8176  C  C     . SER   F 3 351 ? 25.523  72.013  -67.547 1.00 42.92  ? 644  SER   D C     1 
ATOM   8177  O  O     . SER   F 3 351 ? 25.479  71.928  -68.772 1.00 45.72  ? 644  SER   D O     1 
ATOM   8178  C  CB    . SER   F 3 351 ? 27.628  71.977  -66.191 1.00 48.10  ? 644  SER   D CB    1 
ATOM   8179  O  OG    . SER   F 3 351 ? 28.367  71.298  -67.191 1.00 57.09  ? 644  SER   D OG    1 
ATOM   8180  N  N     . TRP   F 3 352 ? 24.642  71.404  -66.760 1.00 43.17  ? 645  TRP   D N     1 
ATOM   8181  C  CA    . TRP   F 3 352 ? 23.547  70.596  -67.269 1.00 48.42  ? 645  TRP   D CA    1 
ATOM   8182  C  C     . TRP   F 3 352 ? 22.570  71.447  -68.085 1.00 49.63  ? 645  TRP   D C     1 
ATOM   8183  O  O     . TRP   F 3 352 ? 22.141  71.063  -69.174 1.00 49.31  ? 645  TRP   D O     1 
ATOM   8184  C  CB    . TRP   F 3 352 ? 22.897  69.911  -66.056 1.00 50.87  ? 645  TRP   D CB    1 
ATOM   8185  C  CG    . TRP   F 3 352 ? 21.547  69.317  -66.268 1.00 61.16  ? 645  TRP   D CG    1 
ATOM   8186  C  CD1   . TRP   F 3 352 ? 21.219  68.214  -67.010 1.00 65.83  ? 645  TRP   D CD1   1 
ATOM   8187  C  CD2   . TRP   F 3 352 ? 20.325  69.787  -65.687 1.00 68.88  ? 645  TRP   D CD2   1 
ATOM   8188  N  NE1   . TRP   F 3 352 ? 19.877  67.960  -66.927 1.00 69.71  ? 645  TRP   D NE1   1 
ATOM   8189  C  CE2   . TRP   F 3 352 ? 19.299  68.913  -66.127 1.00 80.41  ? 645  TRP   D CE2   1 
ATOM   8190  C  CE3   . TRP   F 3 352 ? 20.000  70.827  -64.812 1.00 69.25  ? 645  TRP   D CE3   1 
ATOM   8191  C  CZ2   . TRP   F 3 352 ? 17.968  69.078  -65.746 1.00 80.56  ? 645  TRP   D CZ2   1 
ATOM   8192  C  CZ3   . TRP   F 3 352 ? 18.684  70.995  -64.445 1.00 70.79  ? 645  TRP   D CZ3   1 
ATOM   8193  C  CH2   . TRP   F 3 352 ? 17.687  70.131  -64.904 1.00 78.79  ? 645  TRP   D CH2   1 
ATOM   8194  N  N     . MET   F 3 353 ? 22.200  72.606  -67.533 1.00 50.87  ? 646  MET   D N     1 
ATOM   8195  C  CA    . MET   F 3 353 ? 21.176  73.452  -68.126 1.00 44.51  ? 646  MET   D CA    1 
ATOM   8196  C  C     . MET   F 3 353 ? 21.592  73.906  -69.520 1.00 44.08  ? 646  MET   D C     1 
ATOM   8197  O  O     . MET   F 3 353 ? 20.774  73.890  -70.429 1.00 40.15  ? 646  MET   D O     1 
ATOM   8198  C  CB    . MET   F 3 353 ? 20.979  74.716  -67.290 1.00 46.63  ? 646  MET   D CB    1 
ATOM   8199  C  CG    . MET   F 3 353 ? 20.013  74.541  -66.150 1.00 48.78  ? 646  MET   D CG    1 
ATOM   8200  S  SD    . MET   F 3 353 ? 20.048  76.016  -65.118 1.00 41.15  ? 646  MET   D SD    1 
ATOM   8201  C  CE    . MET   F 3 353 ? 18.792  76.976  -65.970 1.00 39.23  ? 646  MET   D CE    1 
ATOM   8202  N  N     . PHE   F 3 354 ? 22.837  74.381  -69.643 1.00 44.49  ? 647  PHE   D N     1 
ATOM   8203  C  CA    . PHE   F 3 354 ? 23.304  75.057  -70.845 1.00 51.22  ? 647  PHE   D CA    1 
ATOM   8204  C  C     . PHE   F 3 354 ? 24.128  74.105  -71.719 1.00 53.46  ? 647  PHE   D C     1 
ATOM   8205  O  O     . PHE   F 3 354 ? 24.386  74.408  -72.879 1.00 58.05  ? 647  PHE   D O     1 
ATOM   8206  C  CB    . PHE   F 3 354 ? 24.065  76.334  -70.456 1.00 51.51  ? 647  PHE   D CB    1 
ATOM   8207  C  CG    . PHE   F 3 354 ? 23.181  77.400  -69.852 1.00 49.17  ? 647  PHE   D CG    1 
ATOM   8208  C  CD1   . PHE   F 3 354 ? 22.331  78.153  -70.652 1.00 49.43  ? 647  PHE   D CD1   1 
ATOM   8209  C  CD2   . PHE   F 3 354 ? 23.135  77.593  -68.475 1.00 45.94  ? 647  PHE   D CD2   1 
ATOM   8210  C  CE1   . PHE   F 3 354 ? 21.496  79.118  -70.097 1.00 52.40  ? 647  PHE   D CE1   1 
ATOM   8211  C  CE2   . PHE   F 3 354 ? 22.290  78.544  -67.920 1.00 51.39  ? 647  PHE   D CE2   1 
ATOM   8212  C  CZ    . PHE   F 3 354 ? 21.467  79.306  -68.729 1.00 53.26  ? 647  PHE   D CZ    1 
ATOM   8213  N  N     . GLY   F 3 355 ? 24.534  72.957  -71.162 1.00 51.75  ? 648  GLY   D N     1 
ATOM   8214  C  CA    . GLY   F 3 355 ? 25.202  71.924  -71.930 1.00 50.45  ? 648  GLY   D CA    1 
ATOM   8215  C  C     . GLY   F 3 355 ? 26.602  72.374  -72.324 1.00 50.71  ? 648  GLY   D C     1 
ATOM   8216  O  O     . GLY   F 3 355 ? 26.936  72.422  -73.506 1.00 56.71  ? 648  GLY   D O     1 
ATOM   8217  N  N     . VAL   F 3 356 ? 27.380  72.726  -71.298 1.00 48.50  ? 649  VAL   D N     1 
ATOM   8218  C  CA    . VAL   F 3 356 ? 28.728  73.240  -71.450 1.00 50.17  ? 649  VAL   D CA    1 
ATOM   8219  C  C     . VAL   F 3 356 ? 29.511  72.770  -70.235 1.00 45.98  ? 649  VAL   D C     1 
ATOM   8220  O  O     . VAL   F 3 356 ? 28.923  72.499  -69.197 1.00 43.75  ? 649  VAL   D O     1 
ATOM   8221  C  CB    . VAL   F 3 356 ? 28.773  74.786  -71.552 1.00 55.12  ? 649  VAL   D CB    1 
ATOM   8222  C  CG1   . VAL   F 3 356 ? 27.853  75.327  -72.647 1.00 54.77  ? 649  VAL   D CG1   1 
ATOM   8223  C  CG2   . VAL   F 3 356 ? 28.458  75.452  -70.215 1.00 50.98  ? 649  VAL   D CG2   1 
ATOM   8224  N  N     . PRO   F 3 357 ? 30.851  72.648  -70.341 1.00 49.32  ? 650  PRO   D N     1 
ATOM   8225  C  CA    . PRO   F 3 357 ? 31.687  72.317  -69.190 1.00 50.55  ? 650  PRO   D CA    1 
ATOM   8226  C  C     . PRO   F 3 357 ? 31.606  73.356  -68.070 1.00 54.89  ? 650  PRO   D C     1 
ATOM   8227  O  O     . PRO   F 3 357 ? 31.165  74.472  -68.305 1.00 56.44  ? 650  PRO   D O     1 
ATOM   8228  C  CB    . PRO   F 3 357 ? 33.113  72.270  -69.776 1.00 49.94  ? 650  PRO   D CB    1 
ATOM   8229  C  CG    . PRO   F 3 357 ? 32.930  72.095  -71.271 1.00 50.06  ? 650  PRO   D CG    1 
ATOM   8230  C  CD    . PRO   F 3 357 ? 31.619  72.771  -71.594 1.00 50.97  ? 650  PRO   D CD    1 
ATOM   8231  N  N     . ARG   F 3 358 ? 32.093  72.970  -66.884 1.00 59.05  ? 651  ARG   D N     1 
ATOM   8232  C  CA    . ARG   F 3 358 ? 32.154  73.803  -65.693 1.00 66.84  ? 651  ARG   D CA    1 
ATOM   8233  C  C     . ARG   F 3 358 ? 32.826  75.140  -66.014 1.00 71.90  ? 651  ARG   D C     1 
ATOM   8234  O  O     . ARG   F 3 358 ? 32.328  76.190  -65.611 1.00 78.93  ? 651  ARG   D O     1 
ATOM   8235  C  CB    . ARG   F 3 358 ? 32.950  73.110  -64.577 1.00 70.45  ? 651  ARG   D CB    1 
ATOM   8236  C  CG    . ARG   F 3 358 ? 32.560  71.662  -64.291 1.00 75.39  ? 651  ARG   D CG    1 
ATOM   8237  C  CD    . ARG   F 3 358 ? 31.322  71.429  -63.437 1.00 79.84  ? 651  ARG   D CD    1 
ATOM   8238  N  NE    . ARG   F 3 358 ? 30.550  70.244  -63.820 1.00 76.49  ? 651  ARG   D NE    1 
ATOM   8239  C  CZ    . ARG   F 3 358 ? 30.456  69.107  -63.125 1.00 76.51  ? 651  ARG   D CZ    1 
ATOM   8240  N  NH1   . ARG   F 3 358 ? 31.502  68.597  -62.494 1.00 65.26  ? 651  ARG   D NH1   1 
ATOM   8241  N  NH2   . ARG   F 3 358 ? 29.310  68.447  -63.119 1.00 80.90  ? 651  ARG   D NH2   1 
ATOM   8242  N  N     . GLU   F 3 359 ? 33.963  75.094  -66.728 1.00 73.53  ? 652  GLU   D N     1 
ATOM   8243  C  CA    . GLU   F 3 359 ? 34.814  76.261  -66.936 1.00 69.39  ? 652  GLU   D CA    1 
ATOM   8244  C  C     . GLU   F 3 359 ? 34.158  77.265  -67.882 1.00 65.59  ? 652  GLU   D C     1 
ATOM   8245  O  O     . GLU   F 3 359 ? 34.480  78.448  -67.816 1.00 65.16  ? 652  GLU   D O     1 
ATOM   8246  C  CB    . GLU   F 3 359 ? 36.201  75.864  -67.458 1.00 76.53  ? 652  GLU   D CB    1 
ATOM   8247  C  CG    . GLU   F 3 359 ? 37.323  76.000  -66.428 1.00 84.85  ? 652  GLU   D CG    1 
ATOM   8248  C  CD    . GLU   F 3 359 ? 36.998  75.583  -64.998 1.00 91.23  ? 652  GLU   D CD    1 
ATOM   8249  O  OE1   . GLU   F 3 359 ? 36.996  76.472  -64.121 1.00 86.32  ? 652  GLU   D OE1   1 
ATOM   8250  O  OE2   . GLU   F 3 359 ? 36.756  74.374  -64.752 1.00 98.96  ? 652  GLU   D OE2   1 
ATOM   8251  N  N     . ALA   F 3 360 ? 33.247  76.796  -68.744 1.00 56.68  ? 653  ALA   D N     1 
ATOM   8252  C  CA    . ALA   F 3 360 ? 32.542  77.657  -69.680 1.00 53.19  ? 653  ALA   D CA    1 
ATOM   8253  C  C     . ALA   F 3 360 ? 31.237  78.204  -69.086 1.00 57.36  ? 653  ALA   D C     1 
ATOM   8254  O  O     . ALA   F 3 360 ? 30.425  78.781  -69.819 1.00 55.45  ? 653  ALA   D O     1 
ATOM   8255  C  CB    . ALA   F 3 360 ? 32.271  76.904  -70.960 1.00 50.41  ? 653  ALA   D CB    1 
ATOM   8256  N  N     . VAL   F 3 361 ? 31.028  78.039  -67.769 1.00 50.46  ? 654  VAL   D N     1 
ATOM   8257  C  CA    . VAL   F 3 361 ? 29.859  78.620  -67.120 1.00 51.45  ? 654  VAL   D CA    1 
ATOM   8258  C  C     . VAL   F 3 361 ? 30.116  80.114  -66.917 1.00 45.69  ? 654  VAL   D C     1 
ATOM   8259  O  O     . VAL   F 3 361 ? 31.021  80.489  -66.177 1.00 41.14  ? 654  VAL   D O     1 
ATOM   8260  C  CB    . VAL   F 3 361 ? 29.509  77.903  -65.795 1.00 49.84  ? 654  VAL   D CB    1 
ATOM   8261  C  CG1   . VAL   F 3 361 ? 28.390  78.612  -65.035 1.00 49.52  ? 654  VAL   D CG1   1 
ATOM   8262  C  CG2   . VAL   F 3 361 ? 29.132  76.445  -66.035 1.00 49.31  ? 654  VAL   D CG2   1 
ATOM   8263  N  N     . ASN   F 3 362 ? 29.316  80.950  -67.596 1.00 48.15  ? 655  ASN   D N     1 
ATOM   8264  C  CA    . ASN   F 3 362 ? 29.451  82.401  -67.517 1.00 48.13  ? 655  ASN   D CA    1 
ATOM   8265  C  C     . ASN   F 3 362 ? 28.498  82.910  -66.420 1.00 52.40  ? 655  ASN   D C     1 
ATOM   8266  O  O     . ASN   F 3 362 ? 27.585  82.196  -65.986 1.00 50.39  ? 655  ASN   D O     1 
ATOM   8267  C  CB    . ASN   F 3 362 ? 29.293  83.053  -68.904 1.00 38.11  ? 655  ASN   D CB    1 
ATOM   8268  C  CG    . ASN   F 3 362 ? 27.859  83.105  -69.402 1.00 46.52  ? 655  ASN   D CG    1 
ATOM   8269  O  OD1   . ASN   F 3 362 ? 26.919  83.271  -68.619 1.00 44.33  ? 655  ASN   D OD1   1 
ATOM   8270  N  ND2   . ASN   F 3 362 ? 27.654  82.969  -70.707 1.00 43.94  ? 655  ASN   D ND2   1 
ATOM   8271  N  N     . PRO   F 3 363 ? 28.688  84.147  -65.892 1.00 54.04  ? 656  PRO   D N     1 
ATOM   8272  C  CA    . PRO   F 3 363 ? 27.878  84.640  -64.771 1.00 44.56  ? 656  PRO   D CA    1 
ATOM   8273  C  C     . PRO   F 3 363 ? 26.375  84.684  -65.023 1.00 44.80  ? 656  PRO   D C     1 
ATOM   8274  O  O     . PRO   F 3 363 ? 25.580  84.530  -64.096 1.00 47.61  ? 656  PRO   D O     1 
ATOM   8275  C  CB    . PRO   F 3 363 ? 28.419  86.061  -64.539 1.00 49.89  ? 656  PRO   D CB    1 
ATOM   8276  C  CG    . PRO   F 3 363 ? 29.847  86.009  -65.075 1.00 54.88  ? 656  PRO   D CG    1 
ATOM   8277  C  CD    . PRO   F 3 363 ? 29.739  85.107  -66.293 1.00 54.00  ? 656  PRO   D CD    1 
ATOM   8278  N  N     . LEU   F 3 364 ? 25.988  84.884  -66.282 1.00 44.18  ? 657  LEU   D N     1 
ATOM   8279  C  CA    . LEU   F 3 364 ? 24.586  84.839  -66.638 1.00 48.91  ? 657  LEU   D CA    1 
ATOM   8280  C  C     . LEU   F 3 364 ? 24.046  83.441  -66.335 1.00 46.19  ? 657  LEU   D C     1 
ATOM   8281  O  O     . LEU   F 3 364 ? 22.940  83.287  -65.813 1.00 44.26  ? 657  LEU   D O     1 
ATOM   8282  C  CB    . LEU   F 3 364 ? 24.458  85.223  -68.119 1.00 59.78  ? 657  LEU   D CB    1 
ATOM   8283  C  CG    . LEU   F 3 364 ? 23.035  85.365  -68.669 1.00 69.19  ? 657  LEU   D CG    1 
ATOM   8284  C  CD1   . LEU   F 3 364 ? 22.360  86.626  -68.143 1.00 73.06  ? 657  LEU   D CD1   1 
ATOM   8285  C  CD2   . LEU   F 3 364 ? 23.045  85.371  -70.198 1.00 74.60  ? 657  LEU   D CD2   1 
ATOM   8286  N  N     . MET   F 3 365 ? 24.859  82.428  -66.669 1.00 45.41  ? 658  MET   D N     1 
ATOM   8287  C  CA    . MET   F 3 365 ? 24.491  81.025  -66.562 1.00 41.50  ? 658  MET   D CA    1 
ATOM   8288  C  C     . MET   F 3 365 ? 24.386  80.640  -65.085 1.00 37.42  ? 658  MET   D C     1 
ATOM   8289  O  O     . MET   F 3 365 ? 23.434  79.994  -64.663 1.00 36.07  ? 658  MET   D O     1 
ATOM   8290  C  CB    . MET   F 3 365 ? 25.542  80.146  -67.253 1.00 43.46  ? 658  MET   D CB    1 
ATOM   8291  C  CG    . MET   F 3 365 ? 25.426  80.147  -68.778 1.00 45.62  ? 658  MET   D CG    1 
ATOM   8292  S  SD    . MET   F 3 365 ? 26.759  79.236  -69.596 1.00 52.06  ? 658  MET   D SD    1 
ATOM   8293  C  CE    . MET   F 3 365 ? 26.219  79.385  -71.302 1.00 51.16  ? 658  MET   D CE    1 
ATOM   8294  N  N     . ARG   F 3 366 ? 25.374  81.068  -64.306 1.00 33.16  ? 659  ARG   D N     1 
ATOM   8295  C  CA    . ARG   F 3 366 ? 25.402  80.781  -62.888 1.00 37.03  ? 659  ARG   D CA    1 
ATOM   8296  C  C     . ARG   F 3 366 ? 24.147  81.348  -62.207 1.00 37.60  ? 659  ARG   D C     1 
ATOM   8297  O  O     . ARG   F 3 366 ? 23.428  80.624  -61.505 1.00 34.46  ? 659  ARG   D O     1 
ATOM   8298  C  CB    . ARG   F 3 366 ? 26.724  81.294  -62.327 1.00 35.35  ? 659  ARG   D CB    1 
ATOM   8299  C  CG    . ARG   F 3 366 ? 27.106  80.633  -61.015 1.00 40.88  ? 659  ARG   D CG    1 
ATOM   8300  C  CD    . ARG   F 3 366 ? 28.128  81.450  -60.258 1.00 38.41  ? 659  ARG   D CD    1 
ATOM   8301  N  NE    . ARG   F 3 366 ? 28.205  81.005  -58.874 1.00 41.49  ? 659  ARG   D NE    1 
ATOM   8302  C  CZ    . ARG   F 3 366 ? 28.698  79.837  -58.475 1.00 42.28  ? 659  ARG   D CZ    1 
ATOM   8303  N  NH1   . ARG   F 3 366 ? 29.162  78.972  -59.359 1.00 44.06  ? 659  ARG   D NH1   1 
ATOM   8304  N  NH2   . ARG   F 3 366 ? 28.718  79.537  -57.188 1.00 42.94  ? 659  ARG   D NH2   1 
ATOM   8305  N  N     . ARG   F 3 367 ? 23.838  82.616  -62.500 1.00 36.62  ? 660  ARG   D N     1 
ATOM   8306  C  CA    . ARG   F 3 367 ? 22.673  83.289  -61.943 1.00 37.27  ? 660  ARG   D CA    1 
ATOM   8307  C  C     . ARG   F 3 367 ? 21.414  82.514  -62.318 1.00 34.18  ? 660  ARG   D C     1 
ATOM   8308  O  O     . ARG   F 3 367 ? 20.522  82.317  -61.488 1.00 37.12  ? 660  ARG   D O     1 
ATOM   8309  C  CB    . ARG   F 3 367 ? 22.603  84.725  -62.478 1.00 38.57  ? 660  ARG   D CB    1 
ATOM   8310  C  CG    . ARG   F 3 367 ? 21.626  85.678  -61.803 1.00 37.18  ? 660  ARG   D CG    1 
ATOM   8311  C  CD    . ARG   F 3 367 ? 20.513  85.205  -60.889 1.00 37.69  ? 660  ARG   D CD    1 
ATOM   8312  N  NE    . ARG   F 3 367 ? 20.973  85.080  -59.522 1.00 35.41  ? 660  ARG   D NE    1 
ATOM   8313  C  CZ    . ARG   F 3 367 ? 20.223  84.660  -58.501 1.00 38.58  ? 660  ARG   D CZ    1 
ATOM   8314  N  NH1   . ARG   F 3 367 ? 20.585  85.036  -57.284 1.00 35.47  ? 660  ARG   D NH1   1 
ATOM   8315  N  NH2   . ARG   F 3 367 ? 19.124  83.917  -58.681 1.00 32.95  ? 660  ARG   D NH2   1 
ATOM   8316  N  N     . ALA   F 3 368 ? 21.351  82.049  -63.566 1.00 31.89  ? 661  ALA   D N     1 
ATOM   8317  C  CA    . ALA   F 3 368 ? 20.181  81.317  -64.028 1.00 35.07  ? 661  ALA   D CA    1 
ATOM   8318  C  C     . ALA   F 3 368 ? 20.050  79.963  -63.309 1.00 35.02  ? 661  ALA   D C     1 
ATOM   8319  O  O     . ALA   F 3 368 ? 18.938  79.462  -63.089 1.00 30.62  ? 661  ALA   D O     1 
ATOM   8320  C  CB    . ALA   F 3 368 ? 20.287  81.156  -65.525 1.00 37.86  ? 661  ALA   D CB    1 
ATOM   8321  N  N     . ALA   F 3 369 ? 21.201  79.368  -62.963 1.00 32.65  ? 662  ALA   D N     1 
ATOM   8322  C  CA    . ALA   F 3 369 ? 21.255  78.122  -62.209 1.00 33.94  ? 662  ALA   D CA    1 
ATOM   8323  C  C     . ALA   F 3 369 ? 20.839  78.355  -60.758 1.00 32.73  ? 662  ALA   D C     1 
ATOM   8324  O  O     . ALA   F 3 369 ? 20.193  77.498  -60.167 1.00 34.57  ? 662  ALA   D O     1 
ATOM   8325  C  CB    . ALA   F 3 369 ? 22.656  77.533  -62.273 1.00 31.85  ? 662  ALA   D CB    1 
ATOM   8326  N  N     . LYS   F 3 370 ? 21.244  79.497  -60.175 1.00 33.65  ? 663  LYS   D N     1 
ATOM   8327  C  CA    . LYS   F 3 370 ? 20.835  79.851  -58.821 1.00 31.91  ? 663  LYS   D CA    1 
ATOM   8328  C  C     . LYS   F 3 370 ? 19.318  79.929  -58.745 1.00 33.13  ? 663  LYS   D C     1 
ATOM   8329  O  O     . LYS   F 3 370 ? 18.725  79.399  -57.818 1.00 37.53  ? 663  LYS   D O     1 
ATOM   8330  C  CB    . LYS   F 3 370 ? 21.476  81.158  -58.368 1.00 33.66  ? 663  LYS   D CB    1 
ATOM   8331  C  CG    . LYS   F 3 370 ? 22.980  81.064  -58.163 1.00 33.89  ? 663  LYS   D CG    1 
ATOM   8332  C  CD    . LYS   F 3 370 ? 23.571  82.101  -57.269 1.00 35.85  ? 663  LYS   D CD    1 
ATOM   8333  C  CE    . LYS   F 3 370 ? 24.390  83.186  -57.908 1.00 37.09  ? 663  LYS   D CE    1 
ATOM   8334  N  NZ    . LYS   F 3 370 ? 25.645  83.399  -57.133 1.00 38.06  ? 663  LYS   D NZ    1 
ATOM   8335  N  N     . THR   F 3 371 ? 18.680  80.479  -59.779 1.00 33.84  ? 664  THR   D N     1 
ATOM   8336  C  CA    . THR   F 3 371 ? 17.228  80.598  -59.782 1.00 34.57  ? 664  THR   D CA    1 
ATOM   8337  C  C     . THR   F 3 371 ? 16.551  79.220  -59.762 1.00 34.85  ? 664  THR   D C     1 
ATOM   8338  O  O     . THR   F 3 371 ? 15.533  79.044  -59.097 1.00 34.89  ? 664  THR   D O     1 
ATOM   8339  C  CB    . THR   F 3 371 ? 16.777  81.473  -60.957 1.00 35.95  ? 664  THR   D CB    1 
ATOM   8340  O  OG1   . THR   F 3 371 ? 17.344  82.767  -60.756 1.00 35.23  ? 664  THR   D OG1   1 
ATOM   8341  C  CG2   . THR   F 3 371 ? 15.276  81.574  -61.073 1.00 36.57  ? 664  THR   D CG2   1 
ATOM   8342  N  N     . ILE   F 3 372 ? 17.106  78.230  -60.475 1.00 37.14  ? 665  ILE   D N     1 
ATOM   8343  C  CA    . ILE   F 3 372 ? 16.599  76.860  -60.413 1.00 35.08  ? 665  ILE   D CA    1 
ATOM   8344  C  C     . ILE   F 3 372 ? 16.884  76.235  -59.039 1.00 33.02  ? 665  ILE   D C     1 
ATOM   8345  O  O     . ILE   F 3 372 ? 16.002  75.644  -58.436 1.00 30.85  ? 665  ILE   D O     1 
ATOM   8346  C  CB    . ILE   F 3 372 ? 17.190  75.996  -61.548 1.00 36.97  ? 665  ILE   D CB    1 
ATOM   8347  C  CG1   . ILE   F 3 372 ? 16.868  76.567  -62.932 1.00 36.90  ? 665  ILE   D CG1   1 
ATOM   8348  C  CG2   . ILE   F 3 372 ? 16.742  74.539  -61.430 1.00 35.75  ? 665  ILE   D CG2   1 
ATOM   8349  C  CD1   . ILE   F 3 372 ? 15.387  76.667  -63.203 1.00 39.26  ? 665  ILE   D CD1   1 
ATOM   8350  N  N     . ASN   F 3 373 ? 18.124  76.317  -58.551 1.00 32.40  ? 666  ASN   D N     1 
ATOM   8351  C  CA    . ASN   F 3 373 ? 18.514  75.625  -57.325 1.00 31.30  ? 666  ASN   D CA    1 
ATOM   8352  C  C     . ASN   F 3 373 ? 17.714  76.147  -56.119 1.00 33.13  ? 666  ASN   D C     1 
ATOM   8353  O  O     . ASN   F 3 373 ? 17.179  75.379  -55.316 1.00 35.98  ? 666  ASN   D O     1 
ATOM   8354  C  CB    . ASN   F 3 373 ? 20.015  75.770  -57.075 1.00 29.58  ? 666  ASN   D CB    1 
ATOM   8355  C  CG    . ASN   F 3 373 ? 20.911  74.946  -57.987 1.00 32.58  ? 666  ASN   D CG    1 
ATOM   8356  O  OD1   . ASN   F 3 373 ? 22.108  75.216  -58.099 1.00 39.12  ? 666  ASN   D OD1   1 
ATOM   8357  N  ND2   . ASN   F 3 373 ? 20.379  73.928  -58.632 1.00 28.57  ? 666  ASN   D ND2   1 
ATOM   8358  N  N     . PHE   F 3 374 ? 17.631  77.471  -55.986 1.00 31.10  ? 667  PHE   D N     1 
ATOM   8359  C  CA    . PHE   F 3 374 ? 16.902  78.109  -54.902 1.00 30.25  ? 667  PHE   D CA    1 
ATOM   8360  C  C     . PHE   F 3 374 ? 15.407  78.002  -55.154 1.00 31.36  ? 667  PHE   D C     1 
ATOM   8361  O  O     . PHE   F 3 374 ? 14.634  77.821  -54.216 1.00 35.72  ? 667  PHE   D O     1 
ATOM   8362  C  CB    . PHE   F 3 374 ? 17.301  79.580  -54.781 1.00 29.01  ? 667  PHE   D CB    1 
ATOM   8363  C  CG    . PHE   F 3 374 ? 18.752  79.813  -54.427 1.00 29.16  ? 667  PHE   D CG    1 
ATOM   8364  C  CD1   . PHE   F 3 374 ? 19.359  79.100  -53.402 1.00 29.99  ? 667  PHE   D CD1   1 
ATOM   8365  C  CD2   . PHE   F 3 374 ? 19.497  80.786  -55.078 1.00 29.87  ? 667  PHE   D CD2   1 
ATOM   8366  C  CE1   . PHE   F 3 374 ? 20.689  79.326  -53.069 1.00 31.82  ? 667  PHE   D CE1   1 
ATOM   8367  C  CE2   . PHE   F 3 374 ? 20.818  81.033  -54.726 1.00 30.41  ? 667  PHE   D CE2   1 
ATOM   8368  C  CZ    . PHE   F 3 374 ? 21.416  80.291  -53.734 1.00 31.64  ? 667  PHE   D CZ    1 
ATOM   8369  N  N     . GLY   F 3 375 ? 15.018  78.123  -56.426 1.00 31.40  ? 668  GLY   D N     1 
ATOM   8370  C  CA    . GLY   F 3 375 ? 13.627  78.007  -56.828 1.00 30.45  ? 668  GLY   D CA    1 
ATOM   8371  C  C     . GLY   F 3 375 ? 13.007  76.715  -56.320 1.00 31.72  ? 668  GLY   D C     1 
ATOM   8372  O  O     . GLY   F 3 375 ? 12.028  76.732  -55.585 1.00 31.67  ? 668  GLY   D O     1 
ATOM   8373  N  N     . VAL   F 3 376 ? 13.585  75.588  -56.738 1.00 33.40  ? 669  VAL   D N     1 
ATOM   8374  C  CA    . VAL   F 3 376 ? 13.064  74.284  -56.371 1.00 34.79  ? 669  VAL   D CA    1 
ATOM   8375  C  C     . VAL   F 3 376 ? 13.032  74.135  -54.844 1.00 34.82  ? 669  VAL   D C     1 
ATOM   8376  O  O     . VAL   F 3 376 ? 12.018  73.705  -54.296 1.00 34.13  ? 669  VAL   D O     1 
ATOM   8377  C  CB    . VAL   F 3 376 ? 13.875  73.170  -57.055 1.00 36.28  ? 669  VAL   D CB    1 
ATOM   8378  C  CG1   . VAL   F 3 376 ? 13.552  71.800  -56.487 1.00 36.22  ? 669  VAL   D CG1   1 
ATOM   8379  C  CG2   . VAL   F 3 376 ? 13.643  73.199  -58.564 1.00 40.41  ? 669  VAL   D CG2   1 
ATOM   8380  N  N     . LEU   F 3 377 ? 14.136  74.479  -54.169 1.00 31.70  ? 670  LEU   D N     1 
ATOM   8381  C  CA    . LEU   F 3 377 ? 14.214  74.389  -52.724 1.00 31.74  ? 670  LEU   D CA    1 
ATOM   8382  C  C     . LEU   F 3 377 ? 13.089  75.184  -52.055 1.00 34.92  ? 670  LEU   D C     1 
ATOM   8383  O  O     . LEU   F 3 377 ? 12.458  74.662  -51.131 1.00 35.07  ? 670  LEU   D O     1 
ATOM   8384  C  CB    . LEU   F 3 377 ? 15.586  74.892  -52.280 1.00 35.42  ? 670  LEU   D CB    1 
ATOM   8385  C  CG    . LEU   F 3 377 ? 15.725  75.123  -50.773 1.00 35.97  ? 670  LEU   D CG    1 
ATOM   8386  C  CD1   . LEU   F 3 377 ? 15.464  73.835  -50.012 1.00 37.55  ? 670  LEU   D CD1   1 
ATOM   8387  C  CD2   . LEU   F 3 377 ? 17.100  75.677  -50.441 1.00 34.33  ? 670  LEU   D CD2   1 
ATOM   8388  N  N     . TYR   F 3 378 ? 12.835  76.432  -52.506 1.00 31.91  ? 671  TYR   D N     1 
ATOM   8389  C  CA    . TYR   F 3 378 ? 11.894  77.308  -51.811 1.00 30.52  ? 671  TYR   D CA    1 
ATOM   8390  C  C     . TYR   F 3 378 ? 10.486  77.237  -52.406 1.00 30.97  ? 671  TYR   D C     1 
ATOM   8391  O  O     . TYR   F 3 378 ? 9.634   78.037  -52.041 1.00 30.83  ? 671  TYR   D O     1 
ATOM   8392  C  CB    . TYR   F 3 378 ? 12.453  78.730  -51.695 1.00 31.90  ? 671  TYR   D CB    1 
ATOM   8393  C  CG    . TYR   F 3 378 ? 13.651  78.786  -50.776 1.00 30.85  ? 671  TYR   D CG    1 
ATOM   8394  C  CD1   . TYR   F 3 378 ? 13.539  78.438  -49.442 1.00 32.55  ? 671  TYR   D CD1   1 
ATOM   8395  C  CD2   . TYR   F 3 378 ? 14.913  79.100  -51.250 1.00 33.08  ? 671  TYR   D CD2   1 
ATOM   8396  C  CE1   . TYR   F 3 378 ? 14.637  78.423  -48.592 1.00 30.98  ? 671  TYR   D CE1   1 
ATOM   8397  C  CE2   . TYR   F 3 378 ? 16.027  79.083  -50.419 1.00 30.99  ? 671  TYR   D CE2   1 
ATOM   8398  C  CZ    . TYR   F 3 378 ? 15.885  78.748  -49.087 1.00 30.48  ? 671  TYR   D CZ    1 
ATOM   8399  O  OH    . TYR   F 3 378 ? 16.969  78.724  -48.255 1.00 32.34  ? 671  TYR   D OH    1 
ATOM   8400  N  N     . GLY   F 3 379 ? 10.200  76.209  -53.222 1.00 32.94  ? 672  GLY   D N     1 
ATOM   8401  C  CA    . GLY   F 3 379 ? 8.823   75.776  -53.454 1.00 34.22  ? 672  GLY   D CA    1 
ATOM   8402  C  C     . GLY   F 3 379 ? 8.234   76.236  -54.789 1.00 34.41  ? 672  GLY   D C     1 
ATOM   8403  O  O     . GLY   F 3 379 ? 7.028   76.309  -54.929 1.00 34.99  ? 672  GLY   D O     1 
ATOM   8404  N  N     . MET   F 3 380 ? 9.092   76.506  -55.773 1.00 38.68  ? 673  MET   D N     1 
ATOM   8405  C  CA    . MET   F 3 380 ? 8.664   76.834  -57.121 1.00 38.42  ? 673  MET   D CA    1 
ATOM   8406  C  C     . MET   F 3 380 ? 7.852   75.678  -57.697 1.00 38.25  ? 673  MET   D C     1 
ATOM   8407  O  O     . MET   F 3 380 ? 8.266   74.519  -57.618 1.00 39.72  ? 673  MET   D O     1 
ATOM   8408  C  CB    . MET   F 3 380 ? 9.891   77.082  -58.006 1.00 40.73  ? 673  MET   D CB    1 
ATOM   8409  C  CG    . MET   F 3 380 ? 9.563   77.198  -59.491 1.00 39.51  ? 673  MET   D CG    1 
ATOM   8410  S  SD    . MET   F 3 380 ? 10.986  77.610  -60.493 1.00 42.24  ? 673  MET   D SD    1 
ATOM   8411  C  CE    . MET   F 3 380 ? 11.456  79.230  -59.876 1.00 38.98  ? 673  MET   D CE    1 
ATOM   8412  N  N     . SER   F 3 381 ? 6.720   76.019  -58.320 1.00 41.49  ? 674  SER   D N     1 
ATOM   8413  C  CA    . SER   F 3 381 ? 5.806   75.041  -58.897 1.00 42.77  ? 674  SER   D CA    1 
ATOM   8414  C  C     . SER   F 3 381 ? 6.451   74.345  -60.098 1.00 43.06  ? 674  SER   D C     1 
ATOM   8415  O  O     . SER   F 3 381 ? 7.346   74.899  -60.737 1.00 39.70  ? 674  SER   D O     1 
ATOM   8416  C  CB    . SER   F 3 381 ? 4.505   75.703  -59.301 1.00 45.18  ? 674  SER   D CB    1 
ATOM   8417  O  OG    . SER   F 3 381 ? 4.710   76.668  -60.337 1.00 46.58  ? 674  SER   D OG    1 
ATOM   8418  N  N     . ALA   F 3 382 ? 5.967   73.130  -60.403 1.00 47.13  ? 675  ALA   D N     1 
ATOM   8419  C  CA    . ALA   F 3 382 ? 6.397   72.368  -61.571 1.00 48.81  ? 675  ALA   D CA    1 
ATOM   8420  C  C     . ALA   F 3 382 ? 6.095   73.138  -62.860 1.00 50.91  ? 675  ALA   D C     1 
ATOM   8421  O  O     . ALA   F 3 382 ? 6.953   73.218  -63.743 1.00 51.05  ? 675  ALA   D O     1 
ATOM   8422  C  CB    . ALA   F 3 382 ? 5.749   71.000  -61.564 1.00 46.43  ? 675  ALA   D CB    1 
ATOM   8423  N  N     . HIS   F 3 383 ? 4.889   73.719  -62.946 1.00 53.57  ? 676  HIS   D N     1 
ATOM   8424  C  CA    . HIS   F 3 383 ? 4.512   74.548  -64.080 1.00 61.98  ? 676  HIS   D CA    1 
ATOM   8425  C  C     . HIS   F 3 383 ? 5.644   75.526  -64.393 1.00 58.84  ? 676  HIS   D C     1 
ATOM   8426  O  O     . HIS   F 3 383 ? 6.174   75.494  -65.499 1.00 62.26  ? 676  HIS   D O     1 
ATOM   8427  C  CB    . HIS   F 3 383 ? 3.168   75.260  -63.826 1.00 75.90  ? 676  HIS   D CB    1 
ATOM   8428  C  CG    . HIS   F 3 383 ? 2.658   76.119  -64.953 1.00 89.51  ? 676  HIS   D CG    1 
ATOM   8429  N  ND1   . HIS   F 3 383 ? 2.604   75.714  -66.272 1.00 91.34  ? 676  HIS   D ND1   1 
ATOM   8430  C  CD2   . HIS   F 3 383 ? 2.187   77.403  -64.917 1.00 94.76  ? 676  HIS   D CD2   1 
ATOM   8431  C  CE1   . HIS   F 3 383 ? 2.123   76.707  -67.018 1.00 93.42  ? 676  HIS   D CE1   1 
ATOM   8432  N  NE2   . HIS   F 3 383 ? 1.855   77.767  -66.195 1.00 96.27  ? 676  HIS   D NE2   1 
ATOM   8433  N  N     . ARG   F 3 384 ? 6.035   76.360  -63.413 1.00 57.63  ? 677  ARG   D N     1 
ATOM   8434  C  CA    . ARG   F 3 384 ? 6.994   77.435  -63.645 1.00 52.51  ? 677  ARG   D CA    1 
ATOM   8435  C  C     . ARG   F 3 384 ? 8.369   76.864  -63.967 1.00 49.43  ? 677  ARG   D C     1 
ATOM   8436  O  O     . ARG   F 3 384 ? 9.134   77.443  -64.738 1.00 50.30  ? 677  ARG   D O     1 
ATOM   8437  C  CB    . ARG   F 3 384 ? 7.079   78.365  -62.430 1.00 57.37  ? 677  ARG   D CB    1 
ATOM   8438  C  CG    . ARG   F 3 384 ? 8.079   79.511  -62.563 1.00 62.57  ? 677  ARG   D CG    1 
ATOM   8439  C  CD    . ARG   F 3 384 ? 7.770   80.503  -63.674 1.00 71.38  ? 677  ARG   D CD    1 
ATOM   8440  N  NE    . ARG   F 3 384 ? 6.434   81.075  -63.533 1.00 82.33  ? 677  ARG   D NE    1 
ATOM   8441  C  CZ    . ARG   F 3 384 ? 6.033   81.844  -62.520 1.00 86.77  ? 677  ARG   D CZ    1 
ATOM   8442  N  NH1   . ARG   F 3 384 ? 6.858   82.725  -61.982 1.00 85.53  ? 677  ARG   D NH1   1 
ATOM   8443  N  NH2   . ARG   F 3 384 ? 4.790   81.757  -62.070 1.00 90.59  ? 677  ARG   D NH2   1 
ATOM   8444  N  N     . LEU   F 3 385 ? 8.692   75.729  -63.352 1.00 49.17  ? 678  LEU   D N     1 
ATOM   8445  C  CA    . LEU   F 3 385 ? 9.997   75.120  -63.536 1.00 50.43  ? 678  LEU   D CA    1 
ATOM   8446  C  C     . LEU   F 3 385 ? 10.101  74.478  -64.927 1.00 50.66  ? 678  LEU   D C     1 
ATOM   8447  O  O     . LEU   F 3 385 ? 11.177  74.465  -65.519 1.00 44.02  ? 678  LEU   D O     1 
ATOM   8448  C  CB    . LEU   F 3 385 ? 10.180  74.099  -62.412 1.00 49.91  ? 678  LEU   D CB    1 
ATOM   8449  C  CG    . LEU   F 3 385 ? 11.482  73.317  -62.452 1.00 49.13  ? 678  LEU   D CG    1 
ATOM   8450  C  CD1   . LEU   F 3 385 ? 12.650  74.221  -62.088 1.00 49.23  ? 678  LEU   D CD1   1 
ATOM   8451  C  CD2   . LEU   F 3 385 ? 11.387  72.107  -61.527 1.00 54.31  ? 678  LEU   D CD2   1 
ATOM   8452  N  N     . SER   F 3 386 ? 8.984   73.950  -65.446 1.00 50.53  ? 679  SER   D N     1 
ATOM   8453  C  CA    . SER   F 3 386 ? 8.929   73.422  -66.803 1.00 57.53  ? 679  SER   D CA    1 
ATOM   8454  C  C     . SER   F 3 386 ? 9.180   74.532  -67.828 1.00 58.25  ? 679  SER   D C     1 
ATOM   8455  O  O     . SER   F 3 386 ? 9.921   74.322  -68.788 1.00 55.54  ? 679  SER   D O     1 
ATOM   8456  C  CB    . SER   F 3 386 ? 7.620   72.714  -67.065 1.00 62.91  ? 679  SER   D CB    1 
ATOM   8457  O  OG    . SER   F 3 386 ? 6.574   73.640  -67.303 1.00 69.45  ? 679  SER   D OG    1 
ATOM   8458  N  N     . GLN   F 3 387 ? 8.614   75.726  -67.596 1.00 56.43  ? 680  GLN   D N     1 
ATOM   8459  C  CA    . GLN   F 3 387 ? 8.829   76.860  -68.486 1.00 60.75  ? 680  GLN   D CA    1 
ATOM   8460  C  C     . GLN   F 3 387 ? 10.287  77.312  -68.455 1.00 62.74  ? 680  GLN   D C     1 
ATOM   8461  O  O     . GLN   F 3 387 ? 10.839  77.722  -69.469 1.00 72.00  ? 680  GLN   D O     1 
ATOM   8462  C  CB    . GLN   F 3 387 ? 7.956   78.056  -68.102 1.00 67.29  ? 680  GLN   D CB    1 
ATOM   8463  C  CG    . GLN   F 3 387 ? 6.459   77.776  -68.151 1.00 76.37  ? 680  GLN   D CG    1 
ATOM   8464  C  CD    . GLN   F 3 387 ? 5.655   79.033  -67.912 1.00 90.85  ? 680  GLN   D CD    1 
ATOM   8465  O  OE1   . GLN   F 3 387 ? 5.870   79.756  -66.938 1.00 96.74  ? 680  GLN   D OE1   1 
ATOM   8466  N  NE2   . GLN   F 3 387 ? 4.737   79.320  -68.823 1.00 93.72  ? 680  GLN   D NE2   1 
ATOM   8467  N  N     . LYS   F 3 388 ? 10.913  77.228  -67.282 1.00 64.30  ? 681  LYS   D N     1 
ATOM   8468  C  CA    . LYS   F 3 388 ? 12.212  77.838  -67.049 1.00 63.30  ? 681  LYS   D CA    1 
ATOM   8469  C  C     . LYS   F 3 388 ? 13.333  76.903  -67.517 1.00 58.97  ? 681  LYS   D C     1 
ATOM   8470  O  O     . LYS   F 3 388 ? 14.438  77.345  -67.833 1.00 59.49  ? 681  LYS   D O     1 
ATOM   8471  C  CB    . LYS   F 3 388 ? 12.286  78.192  -65.557 1.00 63.41  ? 681  LYS   D CB    1 
ATOM   8472  C  CG    . LYS   F 3 388 ? 12.847  79.563  -65.223 1.00 66.16  ? 681  LYS   D CG    1 
ATOM   8473  C  CD    . LYS   F 3 388 ? 12.184  80.194  -64.022 1.00 68.57  ? 681  LYS   D CD    1 
ATOM   8474  C  CE    . LYS   F 3 388 ? 12.722  81.575  -63.714 1.00 74.97  ? 681  LYS   D CE    1 
ATOM   8475  N  NZ    . LYS   F 3 388 ? 12.707  82.455  -64.908 1.00 75.49  ? 681  LYS   D NZ    1 
ATOM   8476  N  N     . LEU   F 3 389 ? 13.049  75.597  -67.532 1.00 59.71  ? 682  LEU   D N     1 
ATOM   8477  C  CA    . LEU   F 3 389 ? 13.976  74.589  -68.035 1.00 60.27  ? 682  LEU   D CA    1 
ATOM   8478  C  C     . LEU   F 3 389 ? 13.562  74.091  -69.422 1.00 60.41  ? 682  LEU   D C     1 
ATOM   8479  O  O     . LEU   F 3 389 ? 14.289  73.297  -70.021 1.00 61.58  ? 682  LEU   D O     1 
ATOM   8480  C  CB    . LEU   F 3 389 ? 13.984  73.410  -67.058 1.00 53.24  ? 682  LEU   D CB    1 
ATOM   8481  C  CG    . LEU   F 3 389 ? 14.661  73.655  -65.717 1.00 49.46  ? 682  LEU   D CG    1 
ATOM   8482  C  CD1   . LEU   F 3 389 ? 14.453  72.456  -64.806 1.00 49.84  ? 682  LEU   D CD1   1 
ATOM   8483  C  CD2   . LEU   F 3 389 ? 16.139  73.941  -65.913 1.00 48.44  ? 682  LEU   D CD2   1 
ATOM   8484  N  N     . ALA   F 3 390 ? 12.371  74.504  -69.886 1.00 65.06  ? 683  ALA   D N     1 
ATOM   8485  C  CA    . ALA   F 3 390 ? 11.824  74.087  -71.172 1.00 68.30  ? 683  ALA   D CA    1 
ATOM   8486  C  C     . ALA   F 3 390 ? 11.761  72.562  -71.240 1.00 68.74  ? 683  ALA   D C     1 
ATOM   8487  O  O     . ALA   F 3 390 ? 12.390  71.949  -72.099 1.00 78.59  ? 683  ALA   D O     1 
ATOM   8488  C  CB    . ALA   F 3 390 ? 12.643  74.671  -72.307 1.00 66.30  ? 683  ALA   D CB    1 
ATOM   8489  N  N     . ILE   F 3 391 ? 11.011  71.967  -70.303 1.00 60.09  ? 684  ILE   D N     1 
ATOM   8490  C  CA    . ILE   F 3 391 ? 10.822  70.528  -70.238 1.00 56.23  ? 684  ILE   D CA    1 
ATOM   8491  C  C     . ILE   F 3 391 ? 9.344   70.269  -69.974 1.00 54.26  ? 684  ILE   D C     1 
ATOM   8492  O  O     . ILE   F 3 391 ? 8.615   71.164  -69.552 1.00 60.99  ? 684  ILE   D O     1 
ATOM   8493  C  CB    . ILE   F 3 391 ? 11.725  69.872  -69.168 1.00 59.86  ? 684  ILE   D CB    1 
ATOM   8494  C  CG1   . ILE   F 3 391 ? 11.405  70.392  -67.759 1.00 64.03  ? 684  ILE   D CG1   1 
ATOM   8495  C  CG2   . ILE   F 3 391 ? 13.200  70.033  -69.511 1.00 57.19  ? 684  ILE   D CG2   1 
ATOM   8496  C  CD1   . ILE   F 3 391 ? 12.331  69.887  -66.670 1.00 62.85  ? 684  ILE   D CD1   1 
ATOM   8497  N  N     . PRO   F 3 392 ? 8.838   69.050  -70.246 1.00 53.77  ? 685  PRO   D N     1 
ATOM   8498  C  CA    . PRO   F 3 392 ? 7.451   68.726  -69.921 1.00 53.68  ? 685  PRO   D CA    1 
ATOM   8499  C  C     . PRO   F 3 392 ? 7.154   68.813  -68.420 1.00 57.58  ? 685  PRO   D C     1 
ATOM   8500  O  O     . PRO   F 3 392 ? 8.025   68.585  -67.576 1.00 54.33  ? 685  PRO   D O     1 
ATOM   8501  C  CB    . PRO   F 3 392 ? 7.248   67.287  -70.433 1.00 52.05  ? 685  PRO   D CB    1 
ATOM   8502  C  CG    . PRO   F 3 392 ? 8.432   67.003  -71.345 1.00 54.60  ? 685  PRO   D CG    1 
ATOM   8503  C  CD    . PRO   F 3 392 ? 9.539   67.959  -70.944 1.00 55.11  ? 685  PRO   D CD    1 
ATOM   8504  N  N     . TYR   F 3 393 ? 5.890   69.122  -68.121 1.00 54.05  ? 686  TYR   D N     1 
ATOM   8505  C  CA    . TYR   F 3 393 ? 5.378   69.229  -66.774 1.00 56.78  ? 686  TYR   D CA    1 
ATOM   8506  C  C     . TYR   F 3 393 ? 5.876   68.072  -65.909 1.00 65.78  ? 686  TYR   D C     1 
ATOM   8507  O  O     . TYR   F 3 393 ? 6.468   68.302  -64.859 1.00 69.03  ? 686  TYR   D O     1 
ATOM   8508  C  CB    . TYR   F 3 393 ? 3.850   69.247  -66.822 1.00 60.30  ? 686  TYR   D CB    1 
ATOM   8509  C  CG    . TYR   F 3 393 ? 3.192   69.471  -65.486 1.00 62.64  ? 686  TYR   D CG    1 
ATOM   8510  C  CD1   . TYR   F 3 393 ? 3.167   70.734  -64.913 1.00 64.69  ? 686  TYR   D CD1   1 
ATOM   8511  C  CD2   . TYR   F 3 393 ? 2.630   68.419  -64.777 1.00 62.28  ? 686  TYR   D CD2   1 
ATOM   8512  C  CE1   . TYR   F 3 393 ? 2.575   70.952  -63.677 1.00 62.54  ? 686  TYR   D CE1   1 
ATOM   8513  C  CE2   . TYR   F 3 393 ? 2.042   68.621  -63.539 1.00 64.77  ? 686  TYR   D CE2   1 
ATOM   8514  C  CZ    . TYR   F 3 393 ? 2.017   69.892  -62.987 1.00 61.61  ? 686  TYR   D CZ    1 
ATOM   8515  O  OH    . TYR   F 3 393 ? 1.438   70.119  -61.762 1.00 68.53  ? 686  TYR   D OH    1 
ATOM   8516  N  N     . GLU   F 3 394 ? 5.637   66.834  -66.363 1.00 70.54  ? 687  GLU   D N     1 
ATOM   8517  C  CA    . GLU   F 3 394 ? 5.852   65.633  -65.563 1.00 69.78  ? 687  GLU   D CA    1 
ATOM   8518  C  C     . GLU   F 3 394 ? 7.329   65.494  -65.197 1.00 63.47  ? 687  GLU   D C     1 
ATOM   8519  O  O     . GLU   F 3 394 ? 7.665   64.942  -64.149 1.00 58.73  ? 687  GLU   D O     1 
ATOM   8520  C  CB    . GLU   F 3 394 ? 5.407   64.370  -66.315 1.00 76.04  ? 687  GLU   D CB    1 
ATOM   8521  C  CG    . GLU   F 3 394 ? 3.899   64.253  -66.556 1.00 80.87  ? 687  GLU   D CG    1 
ATOM   8522  C  CD    . GLU   F 3 394 ? 3.337   65.071  -67.716 1.00 82.67  ? 687  GLU   D CD    1 
ATOM   8523  O  OE1   . GLU   F 3 394 ? 3.996   65.137  -68.784 1.00 85.11  ? 687  GLU   D OE1   1 
ATOM   8524  O  OE2   . GLU   F 3 394 ? 2.232   65.630  -67.563 1.00 71.60  ? 687  GLU   D OE2   1 
ATOM   8525  N  N     . GLU   F 3 395 ? 8.200   65.977  -66.089 1.00 57.25  ? 688  GLU   D N     1 
ATOM   8526  C  CA    . GLU   F 3 395 ? 9.637   65.879  -65.919 1.00 59.55  ? 688  GLU   D CA    1 
ATOM   8527  C  C     . GLU   F 3 395 ? 10.115  66.933  -64.916 1.00 58.34  ? 688  GLU   D C     1 
ATOM   8528  O  O     . GLU   F 3 395 ? 11.149  66.772  -64.275 1.00 58.56  ? 688  GLU   D O     1 
ATOM   8529  C  CB    . GLU   F 3 395 ? 10.284  66.046  -67.292 1.00 65.92  ? 688  GLU   D CB    1 
ATOM   8530  C  CG    . GLU   F 3 395 ? 11.685  65.473  -67.385 1.00 76.03  ? 688  GLU   D CG    1 
ATOM   8531  C  CD    . GLU   F 3 395 ? 12.373  65.767  -68.709 1.00 83.83  ? 688  GLU   D CD    1 
ATOM   8532  O  OE1   . GLU   F 3 395 ? 11.780  65.440  -69.773 1.00 83.92  ? 688  GLU   D OE1   1 
ATOM   8533  O  OE2   . GLU   F 3 395 ? 13.492  66.330  -68.678 1.00 86.94  ? 688  GLU   D OE2   1 
ATOM   8534  N  N     . ALA   F 3 396 ? 9.353   68.023  -64.800 1.00 54.81  ? 689  ALA   D N     1 
ATOM   8535  C  CA    . ALA   F 3 396 ? 9.598   69.053  -63.807 1.00 50.41  ? 689  ALA   D CA    1 
ATOM   8536  C  C     . ALA   F 3 396 ? 9.201   68.560  -62.418 1.00 48.26  ? 689  ALA   D C     1 
ATOM   8537  O  O     . ALA   F 3 396 ? 9.953   68.784  -61.475 1.00 44.94  ? 689  ALA   D O     1 
ATOM   8538  C  CB    . ALA   F 3 396 ? 8.870   70.323  -64.174 1.00 51.19  ? 689  ALA   D CB    1 
ATOM   8539  N  N     A GLN   F 3 397 ? 8.022   67.915  -62.334 0.50 46.81  ? 690  GLN   D N     1 
ATOM   8540  N  N     B GLN   F 3 397 ? 8.055   67.883  -62.282 0.50 46.42  ? 690  GLN   D N     1 
ATOM   8541  C  CA    A GLN   F 3 397 ? 7.530   67.267  -61.126 0.50 49.15  ? 690  GLN   D CA    1 
ATOM   8542  C  CA    B GLN   F 3 397 ? 7.652   67.388  -60.973 0.50 48.49  ? 690  GLN   D CA    1 
ATOM   8543  C  C     A GLN   F 3 397 ? 8.578   66.290  -60.601 0.50 49.68  ? 690  GLN   D C     1 
ATOM   8544  C  C     B GLN   F 3 397 ? 8.547   66.221  -60.561 0.50 49.71  ? 690  GLN   D C     1 
ATOM   8545  O  O     A GLN   F 3 397 ? 8.819   66.202  -59.399 0.50 51.96  ? 690  GLN   D O     1 
ATOM   8546  O  O     B GLN   F 3 397 ? 8.674   65.951  -59.369 0.50 52.99  ? 690  GLN   D O     1 
ATOM   8547  C  CB    A GLN   F 3 397 ? 6.264   66.441  -61.402 0.50 47.21  ? 690  GLN   D CB    1 
ATOM   8548  C  CB    B GLN   F 3 397 ? 6.169   67.008  -60.941 0.50 46.38  ? 690  GLN   D CB    1 
ATOM   8549  C  CG    A GLN   F 3 397 ? 5.072   67.234  -61.927 0.50 48.91  ? 690  GLN   D CG    1 
ATOM   8550  C  CG    B GLN   F 3 397 ? 5.661   66.614  -59.554 0.50 45.32  ? 690  GLN   D CG    1 
ATOM   8551  C  CD    A GLN   F 3 397 ? 3.773   66.456  -61.883 0.50 48.77  ? 690  GLN   D CD    1 
ATOM   8552  C  CD    B GLN   F 3 397 ? 5.938   67.612  -58.449 0.50 41.16  ? 690  GLN   D CD    1 
ATOM   8553  O  OE1   A GLN   F 3 397 ? 2.912   66.706  -61.041 0.50 46.76  ? 690  GLN   D OE1   1 
ATOM   8554  O  OE1   B GLN   F 3 397 ? 5.485   68.756  -58.472 0.50 36.72  ? 690  GLN   D OE1   1 
ATOM   8555  N  NE2   A GLN   F 3 397 ? 3.617   65.500  -62.788 0.50 42.02  ? 690  GLN   D NE2   1 
ATOM   8556  N  NE2   B GLN   F 3 397 ? 6.675   67.165  -57.444 0.50 39.10  ? 690  GLN   D NE2   1 
ATOM   8557  N  N     . ALA   F 3 398 ? 9.158   65.533  -61.537 1.00 47.68  ? 691  ALA   D N     1 
ATOM   8558  C  CA    . ALA   F 3 398 ? 10.132  64.498  -61.232 1.00 47.58  ? 691  ALA   D CA    1 
ATOM   8559  C  C     . ALA   F 3 398 ? 11.415  65.142  -60.725 1.00 44.80  ? 691  ALA   D C     1 
ATOM   8560  O  O     . ALA   F 3 398 ? 12.058  64.608  -59.829 1.00 45.05  ? 691  ALA   D O     1 
ATOM   8561  C  CB    . ALA   F 3 398 ? 10.406  63.647  -62.460 1.00 47.00  ? 691  ALA   D CB    1 
ATOM   8562  N  N     . PHE   F 3 399 ? 11.795  66.263  -61.348 1.00 42.45  ? 692  PHE   D N     1 
ATOM   8563  C  CA    . PHE   F 3 399 ? 12.989  66.996  -60.964 1.00 41.32  ? 692  PHE   D CA    1 
ATOM   8564  C  C     . PHE   F 3 399 ? 12.906  67.413  -59.496 1.00 41.17  ? 692  PHE   D C     1 
ATOM   8565  O  O     . PHE   F 3 399 ? 13.856  67.225  -58.740 1.00 38.41  ? 692  PHE   D O     1 
ATOM   8566  C  CB    . PHE   F 3 399 ? 13.161  68.237  -61.846 1.00 40.32  ? 692  PHE   D CB    1 
ATOM   8567  C  CG    . PHE   F 3 399 ? 14.411  69.026  -61.543 1.00 40.24  ? 692  PHE   D CG    1 
ATOM   8568  C  CD1   . PHE   F 3 399 ? 14.420  70.006  -60.562 1.00 37.23  ? 692  PHE   D CD1   1 
ATOM   8569  C  CD2   . PHE   F 3 399 ? 15.597  68.743  -62.206 1.00 43.42  ? 692  PHE   D CD2   1 
ATOM   8570  C  CE1   . PHE   F 3 399 ? 15.576  70.718  -60.280 1.00 39.45  ? 692  PHE   D CE1   1 
ATOM   8571  C  CE2   . PHE   F 3 399 ? 16.753  69.456  -61.914 1.00 43.06  ? 692  PHE   D CE2   1 
ATOM   8572  C  CZ    . PHE   F 3 399 ? 16.740  70.437  -60.948 1.00 40.43  ? 692  PHE   D CZ    1 
ATOM   8573  N  N     . ILE   F 3 400 ? 11.767  68.015  -59.133 1.00 38.99  ? 693  ILE   D N     1 
ATOM   8574  C  CA    . ILE   F 3 400 ? 11.479  68.454  -57.779 1.00 39.89  ? 693  ILE   D CA    1 
ATOM   8575  C  C     . ILE   F 3 400 ? 11.600  67.272  -56.815 1.00 41.11  ? 693  ILE   D C     1 
ATOM   8576  O  O     . ILE   F 3 400 ? 12.271  67.365  -55.790 1.00 40.68  ? 693  ILE   D O     1 
ATOM   8577  C  CB    . ILE   F 3 400 ? 10.088  69.123  -57.751 1.00 37.09  ? 693  ILE   D CB    1 
ATOM   8578  C  CG1   . ILE   F 3 400 ? 10.094  70.411  -58.572 1.00 34.19  ? 693  ILE   D CG1   1 
ATOM   8579  C  CG2   . ILE   F 3 400 ? 9.585   69.372  -56.330 1.00 38.48  ? 693  ILE   D CG2   1 
ATOM   8580  C  CD1   . ILE   F 3 400 ? 8.700   70.963  -58.851 1.00 34.39  ? 693  ILE   D CD1   1 
ATOM   8581  N  N     . GLU   F 3 401 ? 11.006  66.139  -57.166 1.00 47.80  ? 694  GLU   D N     1 
ATOM   8582  C  CA    . GLU   F 3 401 ? 10.995  64.979  -56.237 1.00 47.26  ? 694  GLU   D CA    1 
ATOM   8583  C  C     . GLU   F 3 401 ? 12.387  64.339  -56.115 1.00 45.41  ? 694  GLU   D C     1 
ATOM   8584  O  O     . GLU   F 3 401 ? 12.673  63.794  -55.047 1.00 46.00  ? 694  GLU   D O     1 
ATOM   8585  C  CB    . GLU   F 3 401 ? 9.908   63.999  -56.674 1.00 51.18  ? 694  GLU   D CB    1 
ATOM   8586  C  CG    . GLU   F 3 401 ? 8.578   64.256  -55.999 1.00 60.10  ? 694  GLU   D CG    1 
ATOM   8587  C  CD    . GLU   F 3 401 ? 8.677   64.424  -54.494 1.00 71.30  ? 694  GLU   D CD    1 
ATOM   8588  O  OE1   . GLU   F 3 401 ? 8.879   63.408  -53.803 1.00 69.23  ? 694  GLU   D OE1   1 
ATOM   8589  O  OE2   . GLU   F 3 401 ? 8.561   65.570  -54.018 1.00 76.52  ? 694  GLU   D OE2   1 
ATOM   8590  N  N     . ARG   F 3 402 ? 13.217  64.431  -57.152 1.00 41.71  ? 695  ARG   D N     1 
ATOM   8591  C  CA    . ARG   F 3 402 ? 14.593  63.876  -57.102 1.00 43.39  ? 695  ARG   D CA    1 
ATOM   8592  C  C     . ARG   F 3 402 ? 15.475  64.738  -56.198 1.00 41.75  ? 695  ARG   D C     1 
ATOM   8593  O  O     . ARG   F 3 402 ? 16.372  64.179  -55.563 1.00 45.09  ? 695  ARG   D O     1 
ATOM   8594  C  CB    . ARG   F 3 402 ? 15.191  63.760  -58.506 1.00 46.56  ? 695  ARG   D CB    1 
ATOM   8595  C  CG    . ARG   F 3 402 ? 15.014  62.394  -59.149 1.00 50.87  ? 695  ARG   D CG    1 
ATOM   8596  C  CD    . ARG   F 3 402 ? 15.568  62.354  -60.558 1.00 54.84  ? 695  ARG   D CD    1 
ATOM   8597  N  NE    . ARG   F 3 402 ? 15.669  63.679  -61.146 1.00 60.96  ? 695  ARG   D NE    1 
ATOM   8598  C  CZ    . ARG   F 3 402 ? 15.065  64.048  -62.267 1.00 62.40  ? 695  ARG   D CZ    1 
ATOM   8599  N  NH1   . ARG   F 3 402 ? 14.094  63.308  -62.768 1.00 65.63  ? 695  ARG   D NH1   1 
ATOM   8600  N  NH2   . ARG   F 3 402 ? 15.434  65.155  -62.885 1.00 66.11  ? 695  ARG   D NH2   1 
ATOM   8601  N  N     . TYR   F 3 403 ? 15.213  66.042  -56.148 1.00 42.22  ? 696  TYR   D N     1 
ATOM   8602  C  CA    . TYR   F 3 403 ? 16.002  66.943  -55.276 1.00 42.13  ? 696  TYR   D CA    1 
ATOM   8603  C  C     . TYR   F 3 403 ? 15.760  66.543  -53.827 1.00 40.04  ? 696  TYR   D C     1 
ATOM   8604  O  O     . TYR   F 3 403 ? 16.727  66.366  -53.089 1.00 40.00  ? 696  TYR   D O     1 
ATOM   8605  C  CB    . TYR   F 3 403 ? 15.641  68.413  -55.491 1.00 42.06  ? 696  TYR   D CB    1 
ATOM   8606  C  CG    . TYR   F 3 403 ? 16.215  69.337  -54.450 1.00 39.47  ? 696  TYR   D CG    1 
ATOM   8607  C  CD1   . TYR   F 3 403 ? 17.554  69.678  -54.471 1.00 40.41  ? 696  TYR   D CD1   1 
ATOM   8608  C  CD2   . TYR   F 3 403 ? 15.427  69.850  -53.436 1.00 40.26  ? 696  TYR   D CD2   1 
ATOM   8609  C  CE1   . TYR   F 3 403 ? 18.097  70.518  -53.517 1.00 39.62  ? 696  TYR   D CE1   1 
ATOM   8610  C  CE2   . TYR   F 3 403 ? 15.955  70.690  -52.471 1.00 39.10  ? 696  TYR   D CE2   1 
ATOM   8611  C  CZ    . TYR   F 3 403 ? 17.295  71.025  -52.514 1.00 41.22  ? 696  TYR   D CZ    1 
ATOM   8612  O  OH    . TYR   F 3 403 ? 17.839  71.856  -51.573 1.00 42.27  ? 696  TYR   D OH    1 
ATOM   8613  N  N     . PHE   F 3 404 ? 14.493  66.388  -53.465 1.00 40.54  ? 697  PHE   D N     1 
ATOM   8614  C  CA    . PHE   F 3 404 ? 14.165  66.070  -52.082 1.00 44.42  ? 697  PHE   D CA    1 
ATOM   8615  C  C     . PHE   F 3 404 ? 14.447  64.611  -51.708 1.00 50.21  ? 697  PHE   D C     1 
ATOM   8616  O  O     . PHE   F 3 404 ? 14.525  64.301  -50.527 1.00 55.54  ? 697  PHE   D O     1 
ATOM   8617  C  CB    . PHE   F 3 404 ? 12.711  66.476  -51.829 1.00 42.87  ? 697  PHE   D CB    1 
ATOM   8618  C  CG    . PHE   F 3 404 ? 12.524  67.976  -51.782 1.00 43.31  ? 697  PHE   D CG    1 
ATOM   8619  C  CD1   . PHE   F 3 404 ? 13.143  68.740  -50.793 1.00 41.91  ? 697  PHE   D CD1   1 
ATOM   8620  C  CD2   . PHE   F 3 404 ? 11.768  68.641  -52.739 1.00 41.63  ? 697  PHE   D CD2   1 
ATOM   8621  C  CE1   . PHE   F 3 404 ? 12.972  70.116  -50.738 1.00 38.33  ? 697  PHE   D CE1   1 
ATOM   8622  C  CE2   . PHE   F 3 404 ? 11.619  70.023  -52.697 1.00 41.55  ? 697  PHE   D CE2   1 
ATOM   8623  C  CZ    . PHE   F 3 404 ? 12.215  70.759  -51.694 1.00 38.28  ? 697  PHE   D CZ    1 
ATOM   8624  N  N     A GLN   F 3 405 ? 14.580  63.734  -52.717 0.50 53.21  ? 698  GLN   D N     1 
ATOM   8625  N  N     B GLN   F 3 405 ? 14.581  63.721  -52.701 0.50 53.98  ? 698  GLN   D N     1 
ATOM   8626  C  CA    A GLN   F 3 405 ? 15.022  62.355  -52.546 0.50 50.45  ? 698  GLN   D CA    1 
ATOM   8627  C  CA    B GLN   F 3 405 ? 15.029  62.358  -52.454 0.50 51.56  ? 698  GLN   D CA    1 
ATOM   8628  C  C     A GLN   F 3 405 ? 16.525  62.346  -52.270 0.50 49.70  ? 698  GLN   D C     1 
ATOM   8629  C  C     B GLN   F 3 405 ? 16.540  62.364  -52.228 0.50 50.45  ? 698  GLN   D C     1 
ATOM   8630  O  O     A GLN   F 3 405 ? 17.005  61.550  -51.468 0.50 51.57  ? 698  GLN   D O     1 
ATOM   8631  O  O     B GLN   F 3 405 ? 17.042  61.581  -51.427 0.50 52.34  ? 698  GLN   D O     1 
ATOM   8632  C  CB    A GLN   F 3 405 ? 14.697  61.530  -53.805 0.50 52.75  ? 698  GLN   D CB    1 
ATOM   8633  C  CB    B GLN   F 3 405 ? 14.729  61.412  -53.623 0.50 55.37  ? 698  GLN   D CB    1 
ATOM   8634  C  CG    A GLN   F 3 405 ? 15.102  60.057  -53.731 0.50 52.70  ? 698  GLN   D CG    1 
ATOM   8635  C  CG    B GLN   F 3 405 ? 13.281  61.403  -54.102 0.50 57.49  ? 698  GLN   D CG    1 
ATOM   8636  C  CD    A GLN   F 3 405 ? 14.983  59.288  -55.031 0.50 53.55  ? 698  GLN   D CD    1 
ATOM   8637  C  CD    B GLN   F 3 405 ? 12.338  60.538  -53.306 0.50 54.24  ? 698  GLN   D CD    1 
ATOM   8638  O  OE1   A GLN   F 3 405 ? 15.159  58.069  -55.059 0.50 49.61  ? 698  GLN   D OE1   1 
ATOM   8639  O  OE1   B GLN   F 3 405 ? 11.167  60.867  -53.150 0.50 56.51  ? 698  GLN   D OE1   1 
ATOM   8640  N  NE2   A GLN   F 3 405 ? 14.708  59.985  -56.124 0.50 46.11  ? 698  GLN   D NE2   1 
ATOM   8641  N  NE2   B GLN   F 3 405 ? 12.824  59.398  -52.852 0.50 49.56  ? 698  GLN   D NE2   1 
ATOM   8642  N  N     . SER   F 3 406 ? 17.267  63.220  -52.964 1.00 48.50  ? 699  SER   D N     1 
ATOM   8643  C  CA    . SER   F 3 406 ? 18.697  63.392  -52.747 1.00 47.56  ? 699  SER   D CA    1 
ATOM   8644  C  C     . SER   F 3 406 ? 18.986  63.970  -51.353 1.00 45.73  ? 699  SER   D C     1 
ATOM   8645  O  O     . SER   F 3 406 ? 19.968  63.581  -50.725 1.00 50.62  ? 699  SER   D O     1 
ATOM   8646  C  CB    . SER   F 3 406 ? 19.314  64.251  -53.833 1.00 53.14  ? 699  SER   D CB    1 
ATOM   8647  O  OG    . SER   F 3 406 ? 19.272  63.618  -55.107 1.00 56.34  ? 699  SER   D OG    1 
ATOM   8648  N  N     . PHE   F 3 407 ? 18.107  64.871  -50.859 1.00 45.70  ? 700  PHE   D N     1 
ATOM   8649  C  CA    . PHE   F 3 407 ? 18.312  65.639  -49.632 1.00 39.30  ? 700  PHE   D CA    1 
ATOM   8650  C  C     . PHE   F 3 407 ? 17.127  65.442  -48.686 1.00 40.14  ? 700  PHE   D C     1 
ATOM   8651  O  O     . PHE   F 3 407 ? 16.364  66.376  -48.438 1.00 38.53  ? 700  PHE   D O     1 
ATOM   8652  C  CB    . PHE   F 3 407 ? 18.521  67.115  -49.993 1.00 36.20  ? 700  PHE   D CB    1 
ATOM   8653  C  CG    . PHE   F 3 407 ? 19.703  67.317  -50.904 1.00 33.01  ? 700  PHE   D CG    1 
ATOM   8654  C  CD1   . PHE   F 3 407 ? 20.983  67.078  -50.451 1.00 33.75  ? 700  PHE   D CD1   1 
ATOM   8655  C  CD2   . PHE   F 3 407 ? 19.535  67.634  -52.239 1.00 36.06  ? 700  PHE   D CD2   1 
ATOM   8656  C  CE1   . PHE   F 3 407 ? 22.079  67.214  -51.294 1.00 35.42  ? 700  PHE   D CE1   1 
ATOM   8657  C  CE2   . PHE   F 3 407 ? 20.629  67.764  -53.088 1.00 36.80  ? 700  PHE   D CE2   1 
ATOM   8658  C  CZ    . PHE   F 3 407 ? 21.907  67.554  -52.615 1.00 35.67  ? 700  PHE   D CZ    1 
ATOM   8659  N  N     . PRO   F 3 408 ? 16.915  64.212  -48.160 1.00 39.55  ? 701  PRO   D N     1 
ATOM   8660  C  CA    . PRO   F 3 408 ? 15.726  63.915  -47.358 1.00 38.39  ? 701  PRO   D CA    1 
ATOM   8661  C  C     . PRO   F 3 408 ? 15.669  64.615  -45.997 1.00 40.81  ? 701  PRO   D C     1 
ATOM   8662  O  O     . PRO   F 3 408 ? 14.587  64.825  -45.441 1.00 40.13  ? 701  PRO   D O     1 
ATOM   8663  C  CB    . PRO   F 3 408 ? 15.759  62.382  -47.198 1.00 40.58  ? 701  PRO   D CB    1 
ATOM   8664  C  CG    . PRO   F 3 408 ? 17.234  62.006  -47.389 1.00 41.32  ? 701  PRO   D CG    1 
ATOM   8665  C  CD    . PRO   F 3 408 ? 17.787  63.037  -48.355 1.00 39.61  ? 701  PRO   D CD    1 
ATOM   8666  N  N     . LYS   F 3 409 ? 16.814  65.014  -45.444 1.00 39.98  ? 702  LYS   D N     1 
ATOM   8667  C  CA    . LYS   F 3 409 ? 16.747  65.735  -44.181 1.00 42.29  ? 702  LYS   D CA    1 
ATOM   8668  C  C     . LYS   F 3 409 ? 16.376  67.195  -44.420 1.00 39.79  ? 702  LYS   D C     1 
ATOM   8669  O  O     . LYS   F 3 409 ? 15.912  67.860  -43.492 1.00 46.77  ? 702  LYS   D O     1 
ATOM   8670  C  CB    . LYS   F 3 409 ? 18.022  65.537  -43.359 1.00 45.95  ? 702  LYS   D CB    1 
ATOM   8671  C  CG    . LYS   F 3 409 ? 18.308  64.070  -43.047 1.00 47.84  ? 702  LYS   D CG    1 
ATOM   8672  C  CD    . LYS   F 3 409 ? 18.784  63.778  -41.647 1.00 49.89  ? 702  LYS   D CD    1 
ATOM   8673  C  CE    . LYS   F 3 409 ? 19.892  64.687  -41.164 1.00 52.61  ? 702  LYS   D CE    1 
ATOM   8674  N  NZ    . LYS   F 3 409 ? 20.685  64.033  -40.094 1.00 51.68  ? 702  LYS   D NZ    1 
ATOM   8675  N  N     . VAL   F 3 410 ? 16.519  67.683  -45.660 1.00 38.31  ? 703  VAL   D N     1 
ATOM   8676  C  CA    . VAL   F 3 410 ? 16.045  69.022  -45.984 1.00 37.33  ? 703  VAL   D CA    1 
ATOM   8677  C  C     . VAL   F 3 410 ? 14.521  69.042  -45.926 1.00 38.14  ? 703  VAL   D C     1 
ATOM   8678  O  O     . VAL   F 3 410 ? 13.942  69.946  -45.307 1.00 39.37  ? 703  VAL   D O     1 
ATOM   8679  C  CB    . VAL   F 3 410 ? 16.563  69.537  -47.338 1.00 34.81  ? 703  VAL   D CB    1 
ATOM   8680  C  CG1   . VAL   F 3 410 ? 15.871  70.837  -47.743 1.00 32.40  ? 703  VAL   D CG1   1 
ATOM   8681  C  CG2   . VAL   F 3 410 ? 18.078  69.697  -47.321 1.00 33.95  ? 703  VAL   D CG2   1 
ATOM   8682  N  N     . ARG   F 3 411 ? 13.898  68.038  -46.562 1.00 37.64  ? 704  ARG   D N     1 
ATOM   8683  C  CA    . ARG   F 3 411 ? 12.451  67.887  -46.554 1.00 38.12  ? 704  ARG   D CA    1 
ATOM   8684  C  C     . ARG   F 3 411 ? 11.972  67.799  -45.104 1.00 36.74  ? 704  ARG   D C     1 
ATOM   8685  O  O     . ARG   F 3 411 ? 11.013  68.477  -44.731 1.00 37.75  ? 704  ARG   D O     1 
ATOM   8686  C  CB    . ARG   F 3 411 ? 12.051  66.658  -47.381 1.00 45.07  ? 704  ARG   D CB    1 
ATOM   8687  C  CG    . ARG   F 3 411 ? 10.560  66.337  -47.376 1.00 51.89  ? 704  ARG   D CG    1 
ATOM   8688  C  CD    . ARG   F 3 411 ? 9.734   67.043  -48.453 1.00 62.88  ? 704  ARG   D CD    1 
ATOM   8689  N  NE    . ARG   F 3 411 ? 9.457   68.486  -48.310 1.00 66.89  ? 704  ARG   D NE    1 
ATOM   8690  C  CZ    . ARG   F 3 411 ? 8.862   69.233  -49.251 1.00 69.60  ? 704  ARG   D CZ    1 
ATOM   8691  N  NH1   . ARG   F 3 411 ? 8.729   70.542  -49.109 1.00 58.88  ? 704  ARG   D NH1   1 
ATOM   8692  N  NH2   . ARG   F 3 411 ? 8.413   68.662  -50.360 1.00 76.69  ? 704  ARG   D NH2   1 
ATOM   8693  N  N     . ALA   F 3 412 ? 12.658  66.978  -44.288 1.00 35.93  ? 705  ALA   D N     1 
ATOM   8694  C  CA    . ALA   F 3 412 ? 12.254  66.747  -42.903 1.00 36.87  ? 705  ALA   D CA    1 
ATOM   8695  C  C     . ALA   F 3 412 ? 12.362  68.055  -42.113 1.00 35.99  ? 705  ALA   D C     1 
ATOM   8696  O  O     . ALA   F 3 412 ? 11.529  68.328  -41.257 1.00 35.16  ? 705  ALA   D O     1 
ATOM   8697  C  CB    . ALA   F 3 412 ? 13.071  65.637  -42.257 1.00 33.68  ? 705  ALA   D CB    1 
ATOM   8698  N  N     . TRP   F 3 413 ? 13.384  68.855  -42.441 1.00 33.93  ? 706  TRP   D N     1 
ATOM   8699  C  CA    . TRP   F 3 413 ? 13.620  70.141  -41.810 1.00 34.53  ? 706  TRP   D CA    1 
ATOM   8700  C  C     . TRP   F 3 413 ? 12.518  71.132  -42.158 1.00 31.35  ? 706  TRP   D C     1 
ATOM   8701  O  O     . TRP   F 3 413 ? 12.097  71.914  -41.314 1.00 31.36  ? 706  TRP   D O     1 
ATOM   8702  C  CB    . TRP   F 3 413 ? 14.999  70.709  -42.190 1.00 33.37  ? 706  TRP   D CB    1 
ATOM   8703  C  CG    . TRP   F 3 413 ? 15.195  72.065  -41.591 1.00 31.50  ? 706  TRP   D CG    1 
ATOM   8704  C  CD1   . TRP   F 3 413 ? 15.557  72.344  -40.304 1.00 32.96  ? 706  TRP   D CD1   1 
ATOM   8705  C  CD2   . TRP   F 3 413 ? 14.935  73.327  -42.226 1.00 30.10  ? 706  TRP   D CD2   1 
ATOM   8706  N  NE1   . TRP   F 3 413 ? 15.557  73.694  -40.109 1.00 33.68  ? 706  TRP   D NE1   1 
ATOM   8707  C  CE2   . TRP   F 3 413 ? 15.176  74.324  -41.265 1.00 31.92  ? 706  TRP   D CE2   1 
ATOM   8708  C  CE3   . TRP   F 3 413 ? 14.513  73.712  -43.504 1.00 33.26  ? 706  TRP   D CE3   1 
ATOM   8709  C  CZ2   . TRP   F 3 413 ? 15.026  75.683  -41.545 1.00 32.49  ? 706  TRP   D CZ2   1 
ATOM   8710  C  CZ3   . TRP   F 3 413 ? 14.351  75.051  -43.781 1.00 32.53  ? 706  TRP   D CZ3   1 
ATOM   8711  C  CH2   . TRP   F 3 413 ? 14.609  76.023  -42.812 1.00 32.76  ? 706  TRP   D CH2   1 
ATOM   8712  N  N     . ILE   F 3 414 ? 12.110  71.155  -43.423 1.00 33.22  ? 707  ILE   D N     1 
ATOM   8713  C  CA    . ILE   F 3 414 ? 11.038  72.045  -43.837 1.00 35.09  ? 707  ILE   D CA    1 
ATOM   8714  C  C     . ILE   F 3 414 ? 9.775   71.701  -43.043 1.00 40.45  ? 707  ILE   D C     1 
ATOM   8715  O  O     . ILE   F 3 414 ? 9.084   72.597  -42.544 1.00 35.74  ? 707  ILE   D O     1 
ATOM   8716  C  CB    . ILE   F 3 414 ? 10.805  71.940  -45.357 1.00 35.05  ? 707  ILE   D CB    1 
ATOM   8717  C  CG1   . ILE   F 3 414 ? 11.975  72.496  -46.168 1.00 32.16  ? 707  ILE   D CG1   1 
ATOM   8718  C  CG2   . ILE   F 3 414 ? 9.495   72.602  -45.743 1.00 38.87  ? 707  ILE   D CG2   1 
ATOM   8719  C  CD1   . ILE   F 3 414 ? 11.920  72.149  -47.638 1.00 33.97  ? 707  ILE   D CD1   1 
ATOM   8720  N  N     . GLU   F 3 415 ? 9.486   70.391  -42.928 1.00 42.66  ? 708  GLU   D N     1 
ATOM   8721  C  CA    . GLU   F 3 415 ? 8.274   69.925  -42.266 1.00 42.62  ? 708  GLU   D CA    1 
ATOM   8722  C  C     . GLU   F 3 415 ? 8.308   70.272  -40.779 1.00 40.70  ? 708  GLU   D C     1 
ATOM   8723  O  O     . GLU   F 3 415 ? 7.299   70.703  -40.224 1.00 38.21  ? 708  GLU   D O     1 
ATOM   8724  C  CB    . GLU   F 3 415 ? 8.051   68.426  -42.516 1.00 47.66  ? 708  GLU   D CB    1 
ATOM   8725  C  CG    . GLU   F 3 415 ? 7.374   68.143  -43.852 1.00 54.16  ? 708  GLU   D CG    1 
ATOM   8726  C  CD    . GLU   F 3 415 ? 6.162   69.038  -44.121 1.00 64.57  ? 708  GLU   D CD    1 
ATOM   8727  O  OE1   . GLU   F 3 415 ? 6.086   69.609  -45.249 1.00 56.04  ? 708  GLU   D OE1   1 
ATOM   8728  O  OE2   . GLU   F 3 415 ? 5.311   69.214  -43.173 1.00 67.03  ? 708  GLU   D OE2   1 
ATOM   8729  N  N     . LYS   F 3 416 ? 9.465   70.101  -40.135 1.00 38.97  ? 709  LYS   D N     1 
ATOM   8730  C  CA    . LYS   F 3 416 ? 9.572   70.437  -38.724 1.00 40.71  ? 709  LYS   D CA    1 
ATOM   8731  C  C     . LYS   F 3 416 ? 9.355   71.938  -38.510 1.00 37.11  ? 709  LYS   D C     1 
ATOM   8732  O  O     . LYS   F 3 416 ? 8.650   72.346  -37.596 1.00 37.36  ? 709  LYS   D O     1 
ATOM   8733  C  CB    . LYS   F 3 416 ? 10.936  70.020  -38.184 1.00 46.80  ? 709  LYS   D CB    1 
ATOM   8734  C  CG    . LYS   F 3 416 ? 10.986  69.942  -36.669 1.00 55.23  ? 709  LYS   D CG    1 
ATOM   8735  C  CD    . LYS   F 3 416 ? 12.357  69.610  -36.155 1.00 63.78  ? 709  LYS   D CD    1 
ATOM   8736  C  CE    . LYS   F 3 416 ? 12.415  69.575  -34.642 1.00 72.45  ? 709  LYS   D CE    1 
ATOM   8737  N  NZ    . LYS   F 3 416 ? 13.795  69.840  -34.168 1.00 77.27  ? 709  LYS   D NZ    1 
ATOM   8738  N  N     . THR   F 3 417 ? 9.976   72.747  -39.374 1.00 33.87  ? 710  THR   D N     1 
ATOM   8739  C  CA    . THR   F 3 417 ? 9.889   74.194  -39.334 1.00 33.16  ? 710  THR   D CA    1 
ATOM   8740  C  C     . THR   F 3 417 ? 8.441   74.661  -39.453 1.00 32.44  ? 710  THR   D C     1 
ATOM   8741  O  O     . THR   F 3 417 ? 7.986   75.511  -38.682 1.00 38.62  ? 710  THR   D O     1 
ATOM   8742  C  CB    . THR   F 3 417 ? 10.823  74.765  -40.410 1.00 30.94  ? 710  THR   D CB    1 
ATOM   8743  O  OG1   . THR   F 3 417 ? 12.133  74.336  -40.028 1.00 28.44  ? 710  THR   D OG1   1 
ATOM   8744  C  CG2   . THR   F 3 417 ? 10.760  76.269  -40.535 1.00 27.36  ? 710  THR   D CG2   1 
ATOM   8745  N  N     . LEU   F 3 418 ? 7.722   74.101  -40.418 1.00 35.25  ? 711  LEU   D N     1 
ATOM   8746  C  CA    . LEU   F 3 418 ? 6.326   74.449  -40.645 1.00 37.78  ? 711  LEU   D CA    1 
ATOM   8747  C  C     . LEU   F 3 418 ? 5.437   73.994  -39.483 1.00 40.24  ? 711  LEU   D C     1 
ATOM   8748  O  O     . LEU   F 3 418 ? 4.547   74.724  -39.070 1.00 36.40  ? 711  LEU   D O     1 
ATOM   8749  C  CB    . LEU   F 3 418 ? 5.891   73.805  -41.963 1.00 35.26  ? 711  LEU   D CB    1 
ATOM   8750  C  CG    . LEU   F 3 418 ? 6.515   74.425  -43.210 1.00 35.21  ? 711  LEU   D CG    1 
ATOM   8751  C  CD1   . LEU   F 3 418 ? 5.983   73.769  -44.483 1.00 34.57  ? 711  LEU   D CD1   1 
ATOM   8752  C  CD2   . LEU   F 3 418 ? 6.289   75.923  -43.256 1.00 32.75  ? 711  LEU   D CD2   1 
ATOM   8753  N  N     . GLU   F 3 419 ? 5.680   72.790  -38.954 1.00 46.45  ? 712  GLU   D N     1 
ATOM   8754  C  CA    . GLU   F 3 419 ? 4.858   72.222  -37.893 1.00 49.91  ? 712  GLU   D CA    1 
ATOM   8755  C  C     . GLU   F 3 419 ? 4.953   73.104  -36.643 1.00 46.37  ? 712  GLU   D C     1 
ATOM   8756  O  O     . GLU   F 3 419 ? 3.921   73.456  -36.079 1.00 47.57  ? 712  GLU   D O     1 
ATOM   8757  C  CB    . GLU   F 3 419 ? 5.249   70.751  -37.695 1.00 55.06  ? 712  GLU   D CB    1 
ATOM   8758  C  CG    . GLU   F 3 419 ? 4.402   69.974  -36.696 1.00 64.14  ? 712  GLU   D CG    1 
ATOM   8759  C  CD    . GLU   F 3 419 ? 4.788   70.131  -35.229 1.00 77.91  ? 712  GLU   D CD    1 
ATOM   8760  O  OE1   . GLU   F 3 419 ? 6.013   70.230  -34.941 1.00 85.07  ? 712  GLU   D OE1   1 
ATOM   8761  O  OE2   . GLU   F 3 419 ? 3.870   70.113  -34.362 1.00 78.99  ? 712  GLU   D OE2   1 
ATOM   8762  N  N     . GLU   F 3 420 ? 6.181   73.479  -36.250 1.00 45.61  ? 713  GLU   D N     1 
ATOM   8763  C  CA    . GLU   F 3 420 ? 6.465   74.414  -35.164 1.00 45.36  ? 713  GLU   D CA    1 
ATOM   8764  C  C     . GLU   F 3 420 ? 5.862   75.792  -35.452 1.00 42.82  ? 713  GLU   D C     1 
ATOM   8765  O  O     . GLU   F 3 420 ? 5.302   76.422  -34.563 1.00 36.91  ? 713  GLU   D O     1 
ATOM   8766  C  CB    . GLU   F 3 420 ? 7.974   74.678  -35.019 1.00 54.79  ? 713  GLU   D CB    1 
ATOM   8767  C  CG    . GLU   F 3 420 ? 8.769   73.740  -34.130 1.00 64.37  ? 713  GLU   D CG    1 
ATOM   8768  C  CD    . GLU   F 3 420 ? 10.293  73.790  -34.306 1.00 77.06  ? 713  GLU   D CD    1 
ATOM   8769  O  OE1   . GLU   F 3 420 ? 10.830  74.581  -35.182 1.00 60.17  ? 713  GLU   D OE1   1 
ATOM   8770  O  OE2   . GLU   F 3 420 ? 10.971  73.002  -33.590 1.00 69.84  ? 713  GLU   D OE2   1 
ATOM   8771  N  N     . GLY   F 3 421 ? 6.053   76.302  -36.681 1.00 38.23  ? 714  GLY   D N     1 
ATOM   8772  C  CA    . GLY   F 3 421 ? 5.513   77.603  -37.056 1.00 38.63  ? 714  GLY   D CA    1 
ATOM   8773  C  C     . GLY   F 3 421 ? 3.988   77.648  -36.976 1.00 37.74  ? 714  GLY   D C     1 
ATOM   8774  O  O     . GLY   F 3 421 ? 3.382   78.680  -36.654 1.00 34.84  ? 714  GLY   D O     1 
ATOM   8775  N  N     . ARG   F 3 422 ? 3.373   76.499  -37.260 1.00 36.47  ? 715  ARG   D N     1 
ATOM   8776  C  CA    . ARG   F 3 422 ? 1.933   76.335  -37.135 1.00 38.93  ? 715  ARG   D CA    1 
ATOM   8777  C  C     . ARG   F 3 422 ? 1.490   76.479  -35.672 1.00 38.37  ? 715  ARG   D C     1 
ATOM   8778  O  O     . ARG   F 3 422 ? 0.488   77.132  -35.393 1.00 37.85  ? 715  ARG   D O     1 
ATOM   8779  C  CB    . ARG   F 3 422 ? 1.578   74.969  -37.720 1.00 39.51  ? 715  ARG   D CB    1 
ATOM   8780  C  CG    . ARG   F 3 422 ? 0.486   75.009  -38.769 1.00 45.06  ? 715  ARG   D CG    1 
ATOM   8781  C  CD    . ARG   F 3 422 ? 0.810   74.253  -40.041 1.00 46.30  ? 715  ARG   D CD    1 
ATOM   8782  N  NE    . ARG   F 3 422 ? 1.299   72.908  -39.813 1.00 45.88  ? 715  ARG   D NE    1 
ATOM   8783  C  CZ    . ARG   F 3 422 ? 2.051   72.236  -40.680 1.00 42.00  ? 715  ARG   D CZ    1 
ATOM   8784  N  NH1   . ARG   F 3 422 ? 2.173   72.646  -41.932 1.00 36.46  ? 715  ARG   D NH1   1 
ATOM   8785  N  NH2   . ARG   F 3 422 ? 2.679   71.151  -40.278 1.00 44.88  ? 715  ARG   D NH2   1 
ATOM   8786  N  N     . ARG   F 3 423 ? 2.240   75.890  -34.729 1.00 38.94  ? 716  ARG   D N     1 
ATOM   8787  C  CA    . ARG   F 3 423 ? 1.859   75.898  -33.317 1.00 41.89  ? 716  ARG   D CA    1 
ATOM   8788  C  C     . ARG   F 3 423 ? 2.228   77.219  -32.632 1.00 39.89  ? 716  ARG   D C     1 
ATOM   8789  O  O     . ARG   F 3 423 ? 1.466   77.700  -31.808 1.00 43.68  ? 716  ARG   D O     1 
ATOM   8790  C  CB    . ARG   F 3 423 ? 2.495   74.718  -32.575 1.00 45.25  ? 716  ARG   D CB    1 
ATOM   8791  C  CG    . ARG   F 3 423 ? 1.773   73.389  -32.765 1.00 50.86  ? 716  ARG   D CG    1 
ATOM   8792  C  CD    . ARG   F 3 423 ? 2.649   72.176  -32.455 1.00 58.15  ? 716  ARG   D CD    1 
ATOM   8793  N  NE    . ARG   F 3 423 ? 3.432   72.307  -31.230 1.00 60.91  ? 716  ARG   D NE    1 
ATOM   8794  C  CZ    . ARG   F 3 423 ? 4.719   72.655  -31.173 1.00 69.26  ? 716  ARG   D CZ    1 
ATOM   8795  N  NH1   . ARG   F 3 423 ? 5.525   72.458  -32.206 1.00 74.76  ? 716  ARG   D NH1   1 
ATOM   8796  N  NH2   . ARG   F 3 423 ? 5.206   73.186  -30.062 1.00 71.13  ? 716  ARG   D NH2   1 
ATOM   8797  N  N     . ARG   F 3 424 ? 3.377   77.819  -32.975 1.00 38.81  ? 717  ARG   D N     1 
ATOM   8798  C  CA    . ARG   F 3 424 ? 3.851   79.027  -32.313 1.00 38.05  ? 717  ARG   D CA    1 
ATOM   8799  C  C     . ARG   F 3 424 ? 3.368   80.310  -32.993 1.00 32.27  ? 717  ARG   D C     1 
ATOM   8800  O  O     . ARG   F 3 424 ? 3.228   81.340  -32.338 1.00 34.82  ? 717  ARG   D O     1 
ATOM   8801  C  CB    . ARG   F 3 424 ? 5.374   79.054  -32.278 1.00 37.52  ? 717  ARG   D CB    1 
ATOM   8802  C  CG    . ARG   F 3 424 ? 6.031   78.050  -31.339 1.00 43.80  ? 717  ARG   D CG    1 
ATOM   8803  C  CD    . ARG   F 3 424 ? 7.490   78.080  -31.760 1.00 50.86  ? 717  ARG   D CD    1 
ATOM   8804  N  NE    . ARG   F 3 424 ? 8.529   77.469  -30.948 1.00 60.76  ? 717  ARG   D NE    1 
ATOM   8805  C  CZ    . ARG   F 3 424 ? 9.798   77.351  -31.360 1.00 68.57  ? 717  ARG   D CZ    1 
ATOM   8806  N  NH1   . ARG   F 3 424 ? 10.627  76.514  -30.758 1.00 72.31  ? 717  ARG   D NH1   1 
ATOM   8807  N  NH2   . ARG   F 3 424 ? 10.228  78.041  -32.409 1.00 63.16  ? 717  ARG   D NH2   1 
ATOM   8808  N  N     . GLY   F 3 425 ? 3.172   80.261  -34.313 1.00 34.86  ? 718  GLY   D N     1 
ATOM   8809  C  CA    . GLY   F 3 425 ? 2.770   81.415  -35.106 1.00 32.10  ? 718  GLY   D CA    1 
ATOM   8810  C  C     . GLY   F 3 425 ? 3.972   82.230  -35.580 1.00 32.41  ? 718  GLY   D C     1 
ATOM   8811  O  O     . GLY   F 3 425 ? 3.828   83.297  -36.181 1.00 31.96  ? 718  GLY   D O     1 
ATOM   8812  N  N     . TYR   F 3 426 ? 5.170   81.701  -35.317 1.00 35.84  ? 719  TYR   D N     1 
ATOM   8813  C  CA    . TYR   F 3 426 ? 6.402   82.332  -35.755 1.00 34.73  ? 719  TYR   D CA    1 
ATOM   8814  C  C     . TYR   F 3 426 ? 7.438   81.266  -36.067 1.00 32.17  ? 719  TYR   D C     1 
ATOM   8815  O  O     . TYR   F 3 426 ? 7.261   80.109  -35.702 1.00 27.80  ? 719  TYR   D O     1 
ATOM   8816  C  CB    . TYR   F 3 426 ? 6.916   83.328  -34.718 1.00 35.00  ? 719  TYR   D CB    1 
ATOM   8817  C  CG    . TYR   F 3 426 ? 7.338   82.761  -33.389 1.00 37.64  ? 719  TYR   D CG    1 
ATOM   8818  C  CD1   . TYR   F 3 426 ? 8.594   82.193  -33.223 1.00 38.61  ? 719  TYR   D CD1   1 
ATOM   8819  C  CD2   . TYR   F 3 426 ? 6.516   82.868  -32.271 1.00 39.88  ? 719  TYR   D CD2   1 
ATOM   8820  C  CE1   . TYR   F 3 426 ? 9.015   81.728  -31.989 1.00 36.88  ? 719  TYR   D CE1   1 
ATOM   8821  C  CE2   . TYR   F 3 426 ? 6.914   82.377  -31.030 1.00 38.62  ? 719  TYR   D CE2   1 
ATOM   8822  C  CZ    . TYR   F 3 426 ? 8.160   81.786  -30.897 1.00 40.80  ? 719  TYR   D CZ    1 
ATOM   8823  O  OH    . TYR   F 3 426 ? 8.591   81.305  -29.683 1.00 44.11  ? 719  TYR   D OH    1 
ATOM   8824  N  N     . VAL   F 3 427 ? 8.453   81.680  -36.841 1.00 32.77  ? 720  VAL   D N     1 
ATOM   8825  C  CA    . VAL   F 3 427 ? 9.624   80.870  -37.150 1.00 29.91  ? 720  VAL   D CA    1 
ATOM   8826  C  C     . VAL   F 3 427 ? 10.821  81.688  -36.693 1.00 30.09  ? 720  VAL   D C     1 
ATOM   8827  O  O     . VAL   F 3 427 ? 10.664  82.876  -36.391 1.00 28.70  ? 720  VAL   D O     1 
ATOM   8828  C  CB    . VAL   F 3 427 ? 9.696   80.523  -38.649 1.00 31.03  ? 720  VAL   D CB    1 
ATOM   8829  C  CG1   . VAL   F 3 427 ? 8.578   79.571  -39.076 1.00 31.18  ? 720  VAL   D CG1   1 
ATOM   8830  C  CG2   . VAL   F 3 427 ? 9.643   81.767  -39.506 1.00 31.95  ? 720  VAL   D CG2   1 
ATOM   8831  N  N     . GLU   F 3 428 ? 12.003  81.065  -36.608 1.00 30.19  ? 721  GLU   D N     1 
ATOM   8832  C  CA    . GLU   F 3 428 ? 13.121  81.796  -36.039 1.00 33.17  ? 721  GLU   D CA    1 
ATOM   8833  C  C     . GLU   F 3 428 ? 14.440  81.269  -36.590 1.00 31.31  ? 721  GLU   D C     1 
ATOM   8834  O  O     . GLU   F 3 428 ? 14.510  80.188  -37.157 1.00 31.37  ? 721  GLU   D O     1 
ATOM   8835  C  CB    . GLU   F 3 428 ? 13.067  81.765  -34.508 1.00 35.80  ? 721  GLU   D CB    1 
ATOM   8836  C  CG    . GLU   F 3 428 ? 13.057  80.360  -33.946 1.00 44.77  ? 721  GLU   D CG    1 
ATOM   8837  C  CD    . GLU   F 3 428 ? 13.125  80.252  -32.429 1.00 46.63  ? 721  GLU   D CD    1 
ATOM   8838  O  OE1   . GLU   F 3 428 ? 12.560  81.116  -31.736 1.00 45.67  ? 721  GLU   D OE1   1 
ATOM   8839  O  OE2   . GLU   F 3 428 ? 13.774  79.310  -31.958 1.00 53.31  ? 721  GLU   D OE2   1 
ATOM   8840  N  N     . THR   F 3 429 ? 15.455  82.115  -36.467 1.00 27.65  ? 722  THR   D N     1 
ATOM   8841  C  CA    . THR   F 3 429 ? 16.796  81.823  -36.926 1.00 28.10  ? 722  THR   D CA    1 
ATOM   8842  C  C     . THR   F 3 429 ? 17.544  81.066  -35.827 1.00 30.17  ? 722  THR   D C     1 
ATOM   8843  O  O     . THR   F 3 429 ? 17.033  80.852  -34.722 1.00 30.99  ? 722  THR   D O     1 
ATOM   8844  C  CB    . THR   F 3 429 ? 17.531  83.130  -37.268 1.00 24.38  ? 722  THR   D CB    1 
ATOM   8845  O  OG1   . THR   F 3 429 ? 17.831  83.829  -36.062 1.00 23.68  ? 722  THR   D OG1   1 
ATOM   8846  C  CG2   . THR   F 3 429 ? 16.710  84.019  -38.163 1.00 23.62  ? 722  THR   D CG2   1 
ATOM   8847  N  N     . LEU   F 3 430 ? 18.776  80.703  -36.152 1.00 29.19  ? 723  LEU   D N     1 
ATOM   8848  C  CA    . LEU   F 3 430 ? 19.654  79.954  -35.268 1.00 30.72  ? 723  LEU   D CA    1 
ATOM   8849  C  C     . LEU   F 3 430 ? 19.905  80.721  -33.969 1.00 31.35  ? 723  LEU   D C     1 
ATOM   8850  O  O     . LEU   F 3 430 ? 20.155  80.109  -32.933 1.00 35.60  ? 723  LEU   D O     1 
ATOM   8851  C  CB    . LEU   F 3 430 ? 20.947  79.738  -36.059 1.00 30.68  ? 723  LEU   D CB    1 
ATOM   8852  C  CG    . LEU   F 3 430 ? 22.060  78.957  -35.369 1.00 32.87  ? 723  LEU   D CG    1 
ATOM   8853  C  CD1   . LEU   F 3 430 ? 21.717  77.484  -35.324 1.00 32.82  ? 723  LEU   D CD1   1 
ATOM   8854  C  CD2   . LEU   F 3 430 ? 23.373  79.185  -36.106 1.00 32.85  ? 723  LEU   D CD2   1 
ATOM   8855  N  N     . PHE   F 3 431 ? 19.888  82.060  -34.038 1.00 32.87  ? 724  PHE   D N     1 
ATOM   8856  C  CA    . PHE   F 3 431 ? 20.130  82.896  -32.877 1.00 31.48  ? 724  PHE   D CA    1 
ATOM   8857  C  C     . PHE   F 3 431 ? 18.820  83.354  -32.245 1.00 30.74  ? 724  PHE   D C     1 
ATOM   8858  O  O     . PHE   F 3 431 ? 18.823  84.097  -31.276 1.00 36.66  ? 724  PHE   D O     1 
ATOM   8859  C  CB    . PHE   F 3 431 ? 20.969  84.112  -33.261 1.00 37.80  ? 724  PHE   D CB    1 
ATOM   8860  C  CG    . PHE   F 3 431 ? 22.283  83.784  -33.916 1.00 41.70  ? 724  PHE   D CG    1 
ATOM   8861  C  CD1   . PHE   F 3 431 ? 22.346  83.467  -35.262 1.00 44.40  ? 724  PHE   D CD1   1 
ATOM   8862  C  CD2   . PHE   F 3 431 ? 23.449  83.771  -33.179 1.00 44.26  ? 724  PHE   D CD2   1 
ATOM   8863  C  CE1   . PHE   F 3 431 ? 23.562  83.147  -35.844 1.00 46.82  ? 724  PHE   D CE1   1 
ATOM   8864  C  CE2   . PHE   F 3 431 ? 24.664  83.455  -33.767 1.00 45.20  ? 724  PHE   D CE2   1 
ATOM   8865  C  CZ    . PHE   F 3 431 ? 24.719  83.142  -35.094 1.00 44.35  ? 724  PHE   D CZ    1 
ATOM   8866  N  N     . GLY   F 3 432 ? 17.688  82.932  -32.792 1.00 31.29  ? 725  GLY   D N     1 
ATOM   8867  C  CA    . GLY   F 3 432 ? 16.420  83.178  -32.134 1.00 31.07  ? 725  GLY   D CA    1 
ATOM   8868  C  C     . GLY   F 3 432 ? 15.743  84.436  -32.665 1.00 34.21  ? 725  GLY   D C     1 
ATOM   8869  O  O     . GLY   F 3 432 ? 14.709  84.825  -32.129 1.00 40.88  ? 725  GLY   D O     1 
ATOM   8870  N  N     . ARG   F 3 433 ? 16.282  85.056  -33.732 1.00 34.16  ? 726  ARG   D N     1 
ATOM   8871  C  CA    . ARG   F 3 433 ? 15.536  86.101  -34.418 1.00 33.13  ? 726  ARG   D CA    1 
ATOM   8872  C  C     . ARG   F 3 433 ? 14.238  85.504  -34.961 1.00 32.52  ? 726  ARG   D C     1 
ATOM   8873  O  O     . ARG   F 3 433 ? 14.215  84.379  -35.446 1.00 32.15  ? 726  ARG   D O     1 
ATOM   8874  C  CB    . ARG   F 3 433 ? 16.330  86.738  -35.558 1.00 32.88  ? 726  ARG   D CB    1 
ATOM   8875  C  CG    . ARG   F 3 433 ? 15.712  88.024  -36.098 1.00 31.90  ? 726  ARG   D CG    1 
ATOM   8876  C  CD    . ARG   F 3 433 ? 16.334  88.478  -37.409 1.00 31.54  ? 726  ARG   D CD    1 
ATOM   8877  N  NE    . ARG   F 3 433 ? 17.745  88.802  -37.267 1.00 31.18  ? 726  ARG   D NE    1 
ATOM   8878  C  CZ    . ARG   F 3 433 ? 18.205  89.948  -36.770 1.00 32.77  ? 726  ARG   D CZ    1 
ATOM   8879  N  NH1   . ARG   F 3 433 ? 17.374  90.956  -36.522 1.00 28.79  ? 726  ARG   D NH1   1 
ATOM   8880  N  NH2   . ARG   F 3 433 ? 19.499  90.059  -36.505 1.00 31.95  ? 726  ARG   D NH2   1 
ATOM   8881  N  N     . ARG   F 3 434 ? 13.159  86.277  -34.903 1.00 32.41  ? 727  ARG   D N     1 
ATOM   8882  C  CA    . ARG   F 3 434 ? 11.821  85.730  -35.059 1.00 34.83  ? 727  ARG   D CA    1 
ATOM   8883  C  C     . ARG   F 3 434 ? 11.043  86.497  -36.132 1.00 31.22  ? 727  ARG   D C     1 
ATOM   8884  O  O     . ARG   F 3 434 ? 11.187  87.713  -36.264 1.00 29.43  ? 727  ARG   D O     1 
ATOM   8885  C  CB    . ARG   F 3 434 ? 11.228  85.803  -33.653 1.00 40.11  ? 727  ARG   D CB    1 
ATOM   8886  C  CG    . ARG   F 3 434 ? 9.721   85.751  -33.539 1.00 46.96  ? 727  ARG   D CG    1 
ATOM   8887  C  CD    . ARG   F 3 434 ? 9.384   86.130  -32.107 1.00 52.53  ? 727  ARG   D CD    1 
ATOM   8888  N  NE    . ARG   F 3 434 ? 9.975   85.179  -31.176 1.00 55.03  ? 727  ARG   D NE    1 
ATOM   8889  C  CZ    . ARG   F 3 434 ? 9.944   85.302  -29.855 1.00 53.94  ? 727  ARG   D CZ    1 
ATOM   8890  N  NH1   . ARG   F 3 434 ? 9.162   86.215  -29.298 1.00 48.70  ? 727  ARG   D NH1   1 
ATOM   8891  N  NH2   . ARG   F 3 434 ? 10.690  84.503  -29.105 1.00 46.98  ? 727  ARG   D NH2   1 
ATOM   8892  N  N     . ARG   F 3 435 ? 10.246  85.765  -36.920 1.00 29.23  ? 728  ARG   D N     1 
ATOM   8893  C  CA    . ARG   F 3 435 ? 9.302   86.361  -37.848 1.00 29.22  ? 728  ARG   D CA    1 
ATOM   8894  C  C     . ARG   F 3 435 ? 7.941   85.700  -37.640 1.00 30.78  ? 728  ARG   D C     1 
ATOM   8895  O  O     . ARG   F 3 435 ? 7.832   84.485  -37.763 1.00 32.91  ? 728  ARG   D O     1 
ATOM   8896  C  CB    . ARG   F 3 435 ? 9.769   86.178  -39.300 1.00 30.15  ? 728  ARG   D CB    1 
ATOM   8897  C  CG    . ARG   F 3 435 ? 8.829   86.804  -40.316 1.00 29.36  ? 728  ARG   D CG    1 
ATOM   8898  C  CD    . ARG   F 3 435 ? 9.028   86.301  -41.724 1.00 32.80  ? 728  ARG   D CD    1 
ATOM   8899  N  NE    . ARG   F 3 435 ? 8.196   87.026  -42.689 1.00 31.41  ? 728  ARG   D NE    1 
ATOM   8900  C  CZ    . ARG   F 3 435 ? 8.382   86.994  -44.013 1.00 35.07  ? 728  ARG   D CZ    1 
ATOM   8901  N  NH1   . ARG   F 3 435 ? 9.491   86.475  -44.520 1.00 35.78  ? 728  ARG   D NH1   1 
ATOM   8902  N  NH2   . ARG   F 3 435 ? 7.473   87.506  -44.830 1.00 33.85  ? 728  ARG   D NH2   1 
ATOM   8903  N  N     . TYR   F 3 436 ? 6.909   86.515  -37.362 1.00 33.59  ? 729  TYR   D N     1 
ATOM   8904  C  CA    . TYR   F 3 436 ? 5.520   86.068  -37.277 1.00 35.15  ? 729  TYR   D CA    1 
ATOM   8905  C  C     . TYR   F 3 436 ? 4.985   85.828  -38.676 1.00 36.19  ? 729  TYR   D C     1 
ATOM   8906  O  O     . TYR   F 3 436 ? 5.066   86.719  -39.528 1.00 38.45  ? 729  TYR   D O     1 
ATOM   8907  C  CB    . TYR   F 3 436 ? 4.653   87.102  -36.552 1.00 32.62  ? 729  TYR   D CB    1 
ATOM   8908  C  CG    . TYR   F 3 436 ? 5.007   87.163  -35.091 1.00 34.54  ? 729  TYR   D CG    1 
ATOM   8909  C  CD1   . TYR   F 3 436 ? 4.408   86.310  -34.183 1.00 32.27  ? 729  TYR   D CD1   1 
ATOM   8910  C  CD2   . TYR   F 3 436 ? 6.030   87.978  -34.637 1.00 36.29  ? 729  TYR   D CD2   1 
ATOM   8911  C  CE1   . TYR   F 3 436 ? 4.786   86.298  -32.850 1.00 34.77  ? 729  TYR   D CE1   1 
ATOM   8912  C  CE2   . TYR   F 3 436 ? 6.410   87.981  -33.306 1.00 36.85  ? 729  TYR   D CE2   1 
ATOM   8913  C  CZ    . TYR   F 3 436 ? 5.785   87.138  -32.406 1.00 34.22  ? 729  TYR   D CZ    1 
ATOM   8914  O  OH    . TYR   F 3 436 ? 6.151   87.134  -31.080 1.00 33.20  ? 729  TYR   D OH    1 
ATOM   8915  N  N     . VAL   F 3 437 ? 4.474   84.616  -38.896 1.00 35.88  ? 730  VAL   D N     1 
ATOM   8916  C  CA    . VAL   F 3 437 ? 3.922   84.258  -40.189 1.00 40.16  ? 730  VAL   D CA    1 
ATOM   8917  C  C     . VAL   F 3 437 ? 2.489   83.775  -39.997 1.00 40.89  ? 730  VAL   D C     1 
ATOM   8918  O  O     . VAL   F 3 437 ? 2.246   82.630  -39.633 1.00 41.94  ? 730  VAL   D O     1 
ATOM   8919  C  CB    . VAL   F 3 437 ? 4.752   83.215  -40.965 1.00 37.12  ? 730  VAL   D CB    1 
ATOM   8920  C  CG1   . VAL   F 3 437 ? 4.295   83.167  -42.424 1.00 38.30  ? 730  VAL   D CG1   1 
ATOM   8921  C  CG2   . VAL   F 3 437 ? 6.244   83.475  -40.889 1.00 36.63  ? 730  VAL   D CG2   1 
ATOM   8922  N  N     . PRO   F 3 438 ? 1.497   84.642  -40.275 1.00 47.90  ? 731  PRO   D N     1 
ATOM   8923  C  CA    . PRO   F 3 438 ? 0.098   84.231  -40.270 1.00 49.36  ? 731  PRO   D CA    1 
ATOM   8924  C  C     . PRO   F 3 438 ? -0.196  83.399  -41.510 1.00 46.67  ? 731  PRO   D C     1 
ATOM   8925  O  O     . PRO   F 3 438 ? 0.577   83.395  -42.471 1.00 51.07  ? 731  PRO   D O     1 
ATOM   8926  C  CB    . PRO   F 3 438 ? -0.665  85.568  -40.283 1.00 51.06  ? 731  PRO   D CB    1 
ATOM   8927  C  CG    . PRO   F 3 438 ? 0.264   86.534  -40.980 1.00 50.74  ? 731  PRO   D CG    1 
ATOM   8928  C  CD    . PRO   F 3 438 ? 1.664   86.054  -40.655 1.00 51.82  ? 731  PRO   D CD    1 
ATOM   8929  N  N     . ASP   F 3 439 ? -1.363  82.757  -41.515 1.00 46.65  ? 732  ASP   D N     1 
ATOM   8930  C  CA    . ASP   F 3 439 ? -1.863  82.030  -42.715 1.00 46.27  ? 732  ASP   D CA    1 
ATOM   8931  C  C     . ASP   F 3 439 ? -1.183  80.676  -42.903 1.00 43.18  ? 732  ASP   D C     1 
ATOM   8932  O  O     . ASP   F 3 439 ? -1.356  80.086  -43.971 1.00 43.23  ? 732  ASP   D O     1 
ATOM   8933  C  CB    . ASP   F 3 439 ? -1.814  82.912  -43.963 1.00 48.76  ? 732  ASP   D CB    1 
ATOM   8934  C  CG    . ASP   F 3 439 ? -2.651  84.172  -43.855 1.00 53.66  ? 732  ASP   D CG    1 
ATOM   8935  O  OD1   . ASP   F 3 439 ? -3.711  84.114  -43.211 1.00 55.51  ? 732  ASP   D OD1   1 
ATOM   8936  O  OD2   . ASP   F 3 439 ? -2.232  85.196  -44.420 1.00 57.89  ? 732  ASP   D OD2   1 
ATOM   8937  N  N     . LEU   F 3 440 ? -0.484  80.186  -41.890 1.00 43.14  ? 733  LEU   D N     1 
ATOM   8938  C  CA    . LEU   F 3 440 ? 0.089   78.853  -42.024 1.00 45.30  ? 733  LEU   D CA    1 
ATOM   8939  C  C     . LEU   F 3 440 ? -0.995  77.767  -42.025 1.00 51.52  ? 733  LEU   D C     1 
ATOM   8940  O  O     . LEU   F 3 440 ? -0.745  76.655  -42.507 1.00 49.79  ? 733  LEU   D O     1 
ATOM   8941  C  CB    . LEU   F 3 440 ? 1.106   78.638  -40.906 1.00 41.88  ? 733  LEU   D CB    1 
ATOM   8942  C  CG    . LEU   F 3 440 ? 2.461   79.314  -41.132 1.00 43.06  ? 733  LEU   D CG    1 
ATOM   8943  C  CD1   . LEU   F 3 440 ? 3.394   79.050  -39.967 1.00 40.97  ? 733  LEU   D CD1   1 
ATOM   8944  C  CD2   . LEU   F 3 440 ? 3.104   78.842  -42.432 1.00 46.77  ? 733  LEU   D CD2   1 
ATOM   8945  N  N     . GLU   F 3 441 ? -2.186  78.092  -41.491 1.00 54.15  ? 734  GLU   D N     1 
ATOM   8946  C  CA    . GLU   F 3 441 ? -3.312  77.166  -41.465 1.00 61.18  ? 734  GLU   D CA    1 
ATOM   8947  C  C     . GLU   F 3 441 ? -4.502  77.710  -42.260 1.00 60.35  ? 734  GLU   D C     1 
ATOM   8948  O  O     . GLU   F 3 441 ? -5.622  77.260  -42.052 1.00 64.50  ? 734  GLU   D O     1 
ATOM   8949  C  CB    . GLU   F 3 441 ? -3.683  76.839  -40.011 1.00 63.00  ? 734  GLU   D CB    1 
ATOM   8950  C  CG    . GLU   F 3 441 ? -3.055  75.535  -39.519 1.00 61.82  ? 734  GLU   D CG    1 
ATOM   8951  C  CD    . GLU   F 3 441 ? -2.929  75.370  -38.015 1.00 63.68  ? 734  GLU   D CD    1 
ATOM   8952  O  OE1   . GLU   F 3 441 ? -3.050  76.376  -37.284 1.00 67.92  ? 734  GLU   D OE1   1 
ATOM   8953  O  OE2   . GLU   F 3 441 ? -2.720  74.227  -37.573 1.00 68.67  ? 734  GLU   D OE2   1 
ATOM   8954  N  N     . ALA   F 3 442 ? -4.258  78.624  -43.209 1.00 56.24  ? 735  ALA   D N     1 
ATOM   8955  C  CA    . ALA   F 3 442 ? -5.315  79.171  -44.045 1.00 55.61  ? 735  ALA   D CA    1 
ATOM   8956  C  C     . ALA   F 3 442 ? -6.013  78.054  -44.824 1.00 55.89  ? 735  ALA   D C     1 
ATOM   8957  O  O     . ALA   F 3 442 ? -5.411  77.018  -45.109 1.00 65.27  ? 735  ALA   D O     1 
ATOM   8958  C  CB    . ALA   F 3 442 ? -4.747  80.213  -44.970 1.00 54.54  ? 735  ALA   D CB    1 
ATOM   8959  N  N     . ARG   F 3 443 ? -7.291  78.279  -45.165 1.00 61.83  ? 736  ARG   D N     1 
ATOM   8960  C  CA    . ARG   F 3 443 ? -8.141  77.258  -45.772 1.00 63.55  ? 736  ARG   D CA    1 
ATOM   8961  C  C     . ARG   F 3 443 ? -7.836  77.174  -47.267 1.00 58.03  ? 736  ARG   D C     1 
ATOM   8962  O  O     . ARG   F 3 443 ? -7.685  76.077  -47.794 1.00 53.76  ? 736  ARG   D O     1 
ATOM   8963  C  CB    . ARG   F 3 443 ? -9.630  77.533  -45.496 1.00 65.68  ? 736  ARG   D CB    1 
ATOM   8964  N  N     . VAL   F 3 444 ? -7.711  78.338  -47.926 1.00 59.55  ? 737  VAL   D N     1 
ATOM   8965  C  CA    . VAL   F 3 444 ? -7.312  78.420  -49.326 1.00 60.94  ? 737  VAL   D CA    1 
ATOM   8966  C  C     . VAL   F 3 444 ? -5.870  77.912  -49.467 1.00 66.71  ? 737  VAL   D C     1 
ATOM   8967  O  O     . VAL   F 3 444 ? -4.952  78.463  -48.859 1.00 59.75  ? 737  VAL   D O     1 
ATOM   8968  C  CB    . VAL   F 3 444 ? -7.443  79.859  -49.878 1.00 64.78  ? 737  VAL   D CB    1 
ATOM   8969  C  CG1   . VAL   F 3 444 ? -7.277  79.895  -51.392 1.00 62.05  ? 737  VAL   D CG1   1 
ATOM   8970  C  CG2   . VAL   F 3 444 ? -8.752  80.537  -49.499 1.00 63.47  ? 737  VAL   D CG2   1 
ATOM   8971  N  N     . LYS   F 3 445 ? -5.674  76.878  -50.301 1.00 67.96  ? 738  LYS   D N     1 
ATOM   8972  C  CA    . LYS   F 3 445 ? -4.403  76.174  -50.420 1.00 65.28  ? 738  LYS   D CA    1 
ATOM   8973  C  C     . LYS   F 3 445 ? -3.273  77.126  -50.819 1.00 62.80  ? 738  LYS   D C     1 
ATOM   8974  O  O     . LYS   F 3 445 ? -2.193  77.100  -50.235 1.00 54.29  ? 738  LYS   D O     1 
ATOM   8975  C  CB    . LYS   F 3 445 ? -4.524  75.053  -51.461 1.00 72.84  ? 738  LYS   D CB    1 
ATOM   8976  C  CG    . LYS   F 3 445 ? -3.224  74.320  -51.772 1.00 78.10  ? 738  LYS   D CG    1 
ATOM   8977  C  CD    . LYS   F 3 445 ? -3.414  73.003  -52.477 1.00 83.58  ? 738  LYS   D CD    1 
ATOM   8978  C  CE    . LYS   F 3 445 ? -2.167  72.142  -52.423 1.00 88.23  ? 738  LYS   D CE    1 
ATOM   8979  N  NZ    . LYS   F 3 445 ? -2.392  70.817  -53.044 1.00 90.42  ? 738  LYS   D NZ    1 
ATOM   8980  N  N     . SER   F 3 446 ? -3.530  77.959  -51.830 1.00 60.96  ? 739  SER   D N     1 
ATOM   8981  C  CA    . SER   F 3 446 ? -2.523  78.829  -52.417 1.00 60.70  ? 739  SER   D CA    1 
ATOM   8982  C  C     . SER   F 3 446 ? -2.031  79.867  -51.406 1.00 57.26  ? 739  SER   D C     1 
ATOM   8983  O  O     . SER   F 3 446 ? -0.880  80.278  -51.461 1.00 57.67  ? 739  SER   D O     1 
ATOM   8984  C  CB    . SER   F 3 446 ? -3.070  79.505  -53.655 1.00 54.79  ? 739  SER   D CB    1 
ATOM   8985  O  OG    . SER   F 3 446 ? -4.103  80.410  -53.289 1.00 54.33  ? 739  SER   D OG    1 
ATOM   8986  N  N     . VAL   F 3 447 ? -2.923  80.323  -50.519 1.00 56.88  ? 740  VAL   D N     1 
ATOM   8987  C  CA    . VAL   F 3 447 ? -2.584  81.309  -49.503 1.00 54.80  ? 740  VAL   D CA    1 
ATOM   8988  C  C     . VAL   F 3 447 ? -1.798  80.634  -48.365 1.00 49.24  ? 740  VAL   D C     1 
ATOM   8989  O  O     . VAL   F 3 447 ? -0.849  81.212  -47.838 1.00 42.87  ? 740  VAL   D O     1 
ATOM   8990  C  CB    . VAL   F 3 447 ? -3.860  82.044  -49.035 1.00 53.28  ? 740  VAL   D CB    1 
ATOM   8991  C  CG1   . VAL   F 3 447 ? -3.651  82.882  -47.779 1.00 56.30  ? 740  VAL   D CG1   1 
ATOM   8992  C  CG2   . VAL   F 3 447 ? -4.420  82.919  -50.147 1.00 51.99  ? 740  VAL   D CG2   1 
ATOM   8993  N  N     . ARG   F 3 448 ? -2.162  79.394  -48.025 1.00 42.82  ? 741  ARG   D N     1 
ATOM   8994  C  CA    . ARG   F 3 448 ? -1.428  78.617  -47.039 1.00 46.73  ? 741  ARG   D CA    1 
ATOM   8995  C  C     . ARG   F 3 448 ? -0.001  78.348  -47.534 1.00 46.51  ? 741  ARG   D C     1 
ATOM   8996  O  O     . ARG   F 3 448 ? 0.961   78.513  -46.786 1.00 47.01  ? 741  ARG   D O     1 
ATOM   8997  C  CB    . ARG   F 3 448 ? -2.150  77.293  -46.758 1.00 42.16  ? 741  ARG   D CB    1 
ATOM   8998  C  CG    . ARG   F 3 448 ? -1.494  76.444  -45.680 1.00 47.42  ? 741  ARG   D CG    1 
ATOM   8999  C  CD    . ARG   F 3 448 ? -2.225  75.158  -45.358 1.00 51.26  ? 741  ARG   D CD    1 
ATOM   9000  N  NE    . ARG   F 3 448 ? -2.309  74.244  -46.487 1.00 59.51  ? 741  ARG   D NE    1 
ATOM   9001  C  CZ    . ARG   F 3 448 ? -3.399  74.054  -47.238 1.00 69.75  ? 741  ARG   D CZ    1 
ATOM   9002  N  NH1   . ARG   F 3 448 ? -4.518  74.737  -47.018 1.00 60.23  ? 741  ARG   D NH1   1 
ATOM   9003  N  NH2   . ARG   F 3 448 ? -3.345  73.190  -48.239 1.00 74.52  ? 741  ARG   D NH2   1 
ATOM   9004  N  N     . GLN   F 3 449 ? 0.120   77.920  -48.797 1.00 42.66  ? 742  GLN   D N     1 
ATOM   9005  C  CA    . GLN   F 3 449 ? 1.376   77.441  -49.348 1.00 42.88  ? 742  GLN   D CA    1 
ATOM   9006  C  C     . GLN   F 3 449 ? 2.342   78.607  -49.482 1.00 41.12  ? 742  GLN   D C     1 
ATOM   9007  O  O     . GLN   F 3 449 ? 3.527   78.438  -49.234 1.00 38.76  ? 742  GLN   D O     1 
ATOM   9008  C  CB    . GLN   F 3 449 ? 1.157   76.730  -50.685 1.00 46.36  ? 742  GLN   D CB    1 
ATOM   9009  C  CG    . GLN   F 3 449 ? 0.630   75.309  -50.498 1.00 51.11  ? 742  GLN   D CG    1 
ATOM   9010  C  CD    . GLN   F 3 449 ? 0.720   74.459  -51.740 1.00 51.47  ? 742  GLN   D CD    1 
ATOM   9011  O  OE1   . GLN   F 3 449 ? 0.431   74.920  -52.842 1.00 54.12  ? 742  GLN   D OE1   1 
ATOM   9012  N  NE2   . GLN   F 3 449 ? 1.116   73.208  -51.559 1.00 46.74  ? 742  GLN   D NE2   1 
ATOM   9013  N  N     . ALA   F 3 450 ? 1.805   79.779  -49.828 1.00 37.24  ? 743  ALA   D N     1 
ATOM   9014  C  CA    . ALA   F 3 450 ? 2.586   80.996  -49.900 1.00 39.44  ? 743  ALA   D CA    1 
ATOM   9015  C  C     . ALA   F 3 450 ? 3.192   81.312  -48.536 1.00 38.87  ? 743  ALA   D C     1 
ATOM   9016  O  O     . ALA   F 3 450 ? 4.385   81.598  -48.444 1.00 39.02  ? 743  ALA   D O     1 
ATOM   9017  C  CB    . ALA   F 3 450 ? 1.711   82.126  -50.385 1.00 41.81  ? 743  ALA   D CB    1 
ATOM   9018  N  N     . ALA   F 3 451 ? 2.346   81.254  -47.496 1.00 36.23  ? 744  ALA   D N     1 
ATOM   9019  C  CA    . ALA   F 3 451 ? 2.750   81.515  -46.125 1.00 34.69  ? 744  ALA   D CA    1 
ATOM   9020  C  C     . ALA   F 3 451 ? 3.879   80.574  -45.721 1.00 34.12  ? 744  ALA   D C     1 
ATOM   9021  O  O     . ALA   F 3 451 ? 4.856   81.010  -45.128 1.00 37.07  ? 744  ALA   D O     1 
ATOM   9022  C  CB    . ALA   F 3 451 ? 1.565   81.345  -45.209 1.00 35.40  ? 744  ALA   D CB    1 
ATOM   9023  N  N     . GLU   F 3 452 ? 3.716   79.294  -46.078 1.00 33.82  ? 745  GLU   D N     1 
ATOM   9024  C  CA    . GLU   F 3 452 ? 4.701   78.254  -45.846 1.00 36.03  ? 745  GLU   D CA    1 
ATOM   9025  C  C     . GLU   F 3 452 ? 6.056   78.629  -46.451 1.00 36.49  ? 745  GLU   D C     1 
ATOM   9026  O  O     . GLU   F 3 452 ? 7.070   78.498  -45.761 1.00 34.95  ? 745  GLU   D O     1 
ATOM   9027  C  CB    . GLU   F 3 452 ? 4.188   76.916  -46.392 1.00 37.65  ? 745  GLU   D CB    1 
ATOM   9028  C  CG    . GLU   F 3 452 ? 3.063   76.302  -45.548 1.00 40.98  ? 745  GLU   D CG    1 
ATOM   9029  C  CD    . GLU   F 3 452 ? 2.494   74.967  -46.032 1.00 40.16  ? 745  GLU   D CD    1 
ATOM   9030  O  OE1   . GLU   F 3 452 ? 2.779   74.570  -47.173 1.00 36.07  ? 745  GLU   D OE1   1 
ATOM   9031  O  OE2   . GLU   F 3 452 ? 1.779   74.311  -45.250 1.00 44.07  ? 745  GLU   D OE2   1 
ATOM   9032  N  N     . ARG   F 3 453 ? 6.076   79.085  -47.719 1.00 35.93  ? 746  ARG   D N     1 
ATOM   9033  C  CA    . ARG   F 3 453 ? 7.327   79.393  -48.410 1.00 36.64  ? 746  ARG   D CA    1 
ATOM   9034  C  C     . ARG   F 3 453 ? 8.050   80.535  -47.702 1.00 34.59  ? 746  ARG   D C     1 
ATOM   9035  O  O     . ARG   F 3 453 ? 9.262   80.450  -47.480 1.00 32.28  ? 746  ARG   D O     1 
ATOM   9036  C  CB    . ARG   F 3 453 ? 7.087   79.700  -49.892 1.00 35.48  ? 746  ARG   D CB    1 
ATOM   9037  C  CG    . ARG   F 3 453 ? 6.610   78.482  -50.672 1.00 35.84  ? 746  ARG   D CG    1 
ATOM   9038  C  CD    . ARG   F 3 453 ? 6.510   78.699  -52.166 1.00 38.17  ? 746  ARG   D CD    1 
ATOM   9039  N  NE    . ARG   F 3 453 ? 5.625   79.801  -52.502 1.00 39.53  ? 746  ARG   D NE    1 
ATOM   9040  C  CZ    . ARG   F 3 453 ? 4.358   79.646  -52.869 1.00 41.85  ? 746  ARG   D CZ    1 
ATOM   9041  N  NH1   . ARG   F 3 453 ? 3.794   78.454  -52.818 1.00 37.34  ? 746  ARG   D NH1   1 
ATOM   9042  N  NH2   . ARG   F 3 453 ? 3.647   80.692  -53.250 1.00 41.93  ? 746  ARG   D NH2   1 
ATOM   9043  N  N     . ARG   F 3 454 ? 7.280   81.555  -47.284 1.00 34.33  ? 747  ARG   D N     1 
ATOM   9044  C  CA    . ARG   F 3 454 ? 7.818   82.664  -46.502 1.00 36.49  ? 747  ARG   D CA    1 
ATOM   9045  C  C     . ARG   F 3 454 ? 8.421   82.153  -45.194 1.00 39.82  ? 747  ARG   D C     1 
ATOM   9046  O  O     . ARG   F 3 454 ? 9.489   82.607  -44.785 1.00 40.57  ? 747  ARG   D O     1 
ATOM   9047  C  CB    . ARG   F 3 454 ? 6.745   83.719  -46.208 1.00 38.67  ? 747  ARG   D CB    1 
ATOM   9048  C  CG    . ARG   F 3 454 ? 6.198   84.407  -47.453 1.00 41.89  ? 747  ARG   D CG    1 
ATOM   9049  C  CD    . ARG   F 3 454 ? 5.454   85.706  -47.185 1.00 41.93  ? 747  ARG   D CD    1 
ATOM   9050  N  NE    . ARG   F 3 454 ? 4.126   85.525  -46.638 1.00 45.30  ? 747  ARG   D NE    1 
ATOM   9051  C  CZ    . ARG   F 3 454 ? 3.041   85.164  -47.322 1.00 48.29  ? 747  ARG   D CZ    1 
ATOM   9052  N  NH1   . ARG   F 3 454 ? 1.949   84.784  -46.679 1.00 47.27  ? 747  ARG   D NH1   1 
ATOM   9053  N  NH2   . ARG   F 3 454 ? 3.040   85.177  -48.638 1.00 49.20  ? 747  ARG   D NH2   1 
ATOM   9054  N  N     . ALA   F 3 455 ? 7.754   81.168  -44.573 1.00 38.58  ? 748  ALA   D N     1 
ATOM   9055  C  CA    . ALA   F 3 455 ? 8.110   80.719  -43.241 1.00 36.00  ? 748  ALA   D CA    1 
ATOM   9056  C  C     . ALA   F 3 455 ? 9.373   79.863  -43.242 1.00 32.67  ? 748  ALA   D C     1 
ATOM   9057  O  O     . ALA   F 3 455 ? 10.209  80.028  -42.360 1.00 38.82  ? 748  ALA   D O     1 
ATOM   9058  C  CB    . ALA   F 3 455 ? 6.935   80.001  -42.631 1.00 37.30  ? 748  ALA   D CB    1 
ATOM   9059  N  N     . PHE   F 3 456 ? 9.516   78.900  -44.160 1.00 31.30  ? 749  PHE   D N     1 
ATOM   9060  C  CA    . PHE   F 3 456 ? 10.691  78.033  -44.090 1.00 30.90  ? 749  PHE   D CA    1 
ATOM   9061  C  C     . PHE   F 3 456 ? 11.893  78.682  -44.781 1.00 29.47  ? 749  PHE   D C     1 
ATOM   9062  O  O     . PHE   F 3 456 ? 13.020  78.242  -44.584 1.00 29.51  ? 749  PHE   D O     1 
ATOM   9063  C  CB    . PHE   F 3 456 ? 10.397  76.598  -44.549 1.00 31.80  ? 749  PHE   D CB    1 
ATOM   9064  C  CG    . PHE   F 3 456 ? 10.219  76.331  -46.023 1.00 32.85  ? 749  PHE   D CG    1 
ATOM   9065  C  CD1   . PHE   F 3 456 ? 11.317  76.188  -46.859 1.00 32.23  ? 749  PHE   D CD1   1 
ATOM   9066  C  CD2   . PHE   F 3 456 ? 8.950   76.120  -46.555 1.00 34.13  ? 749  PHE   D CD2   1 
ATOM   9067  C  CE1   . PHE   F 3 456 ? 11.151  75.892  -48.203 1.00 33.23  ? 749  PHE   D CE1   1 
ATOM   9068  C  CE2   . PHE   F 3 456 ? 8.783   75.847  -47.907 1.00 34.15  ? 749  PHE   D CE2   1 
ATOM   9069  C  CZ    . PHE   F 3 456 ? 9.886   75.727  -48.725 1.00 32.85  ? 749  PHE   D CZ    1 
ATOM   9070  N  N     . ASN   F 3 457 ? 11.666  79.749  -45.553 1.00 27.40  ? 750  ASN   D N     1 
ATOM   9071  C  CA    . ASN   F 3 457 ? 12.768  80.503  -46.111 1.00 29.86  ? 750  ASN   D CA    1 
ATOM   9072  C  C     . ASN   F 3 457 ? 13.466  81.302  -45.006 1.00 30.67  ? 750  ASN   D C     1 
ATOM   9073  O  O     . ASN   F 3 457 ? 14.688  81.451  -45.026 1.00 31.47  ? 750  ASN   D O     1 
ATOM   9074  C  CB    . ASN   F 3 457 ? 12.307  81.445  -47.231 1.00 29.97  ? 750  ASN   D CB    1 
ATOM   9075  C  CG    . ASN   F 3 457 ? 13.424  82.359  -47.694 1.00 30.28  ? 750  ASN   D CG    1 
ATOM   9076  O  OD1   . ASN   F 3 457 ? 14.293  81.959  -48.474 1.00 35.44  ? 750  ASN   D OD1   1 
ATOM   9077  N  ND2   . ASN   F 3 457 ? 13.435  83.576  -47.189 1.00 29.11  ? 750  ASN   D ND2   1 
ATOM   9078  N  N     . MET   F 3 458 ? 12.691  81.831  -44.049 1.00 29.84  ? 751  MET   D N     1 
ATOM   9079  C  CA    . MET   F 3 458 ? 13.203  82.891  -43.190 1.00 30.69  ? 751  MET   D CA    1 
ATOM   9080  C  C     . MET   F 3 458 ? 14.385  82.407  -42.351 1.00 31.16  ? 751  MET   D C     1 
ATOM   9081  O  O     . MET   F 3 458 ? 15.399  83.118  -42.246 1.00 31.73  ? 751  MET   D O     1 
ATOM   9082  C  CB    . MET   F 3 458 ? 12.130  83.481  -42.267 1.00 28.47  ? 751  MET   D CB    1 
ATOM   9083  C  CG    . MET   F 3 458 ? 12.669  84.555  -41.339 1.00 27.61  ? 751  MET   D CG    1 
ATOM   9084  S  SD    . MET   F 3 458 ? 12.906  83.979  -39.646 1.00 30.13  ? 751  MET   D SD    1 
ATOM   9085  C  CE    . MET   F 3 458 ? 13.535  85.495  -38.916 1.00 27.95  ? 751  MET   D CE    1 
ATOM   9086  N  N     . PRO   F 3 459 ? 14.299  81.230  -41.689 1.00 27.91  ? 752  PRO   D N     1 
ATOM   9087  C  CA    . PRO   F 3 459 ? 15.395  80.769  -40.837 1.00 27.52  ? 752  PRO   D CA    1 
ATOM   9088  C  C     . PRO   F 3 459 ? 16.725  80.687  -41.580 1.00 29.37  ? 752  PRO   D C     1 
ATOM   9089  O  O     . PRO   F 3 459 ? 17.780  80.892  -40.978 1.00 34.11  ? 752  PRO   D O     1 
ATOM   9090  C  CB    . PRO   F 3 459 ? 14.946  79.378  -40.357 1.00 27.59  ? 752  PRO   D CB    1 
ATOM   9091  C  CG    . PRO   F 3 459 ? 13.432  79.414  -40.461 1.00 25.91  ? 752  PRO   D CG    1 
ATOM   9092  C  CD    . PRO   F 3 459 ? 13.143  80.320  -41.648 1.00 27.81  ? 752  PRO   D CD    1 
ATOM   9093  N  N     . VAL   F 3 460 ? 16.669  80.395  -42.886 1.00 28.17  ? 753  VAL   D N     1 
ATOM   9094  C  CA    . VAL   F 3 460 ? 17.873  80.290  -43.686 1.00 30.64  ? 753  VAL   D CA    1 
ATOM   9095  C  C     . VAL   F 3 460 ? 18.389  81.695  -44.004 1.00 29.32  ? 753  VAL   D C     1 
ATOM   9096  O  O     . VAL   F 3 460 ? 19.545  82.011  -43.731 1.00 30.71  ? 753  VAL   D O     1 
ATOM   9097  C  CB    . VAL   F 3 460 ? 17.635  79.467  -44.973 1.00 32.74  ? 753  VAL   D CB    1 
ATOM   9098  C  CG1   . VAL   F 3 460 ? 18.916  79.342  -45.802 1.00 32.25  ? 753  VAL   D CG1   1 
ATOM   9099  C  CG2   . VAL   F 3 460 ? 17.093  78.081  -44.672 1.00 32.37  ? 753  VAL   D CG2   1 
ATOM   9100  N  N     . GLN   F 3 461 ? 17.531  82.530  -44.596 1.00 28.64  ? 754  GLN   D N     1 
ATOM   9101  C  CA    . GLN   F 3 461 ? 17.913  83.881  -44.993 1.00 28.35  ? 754  GLN   D CA    1 
ATOM   9102  C  C     . GLN   F 3 461 ? 18.342  84.696  -43.769 1.00 27.40  ? 754  GLN   D C     1 
ATOM   9103  O  O     . GLN   F 3 461 ? 19.321  85.450  -43.821 1.00 32.13  ? 754  GLN   D O     1 
ATOM   9104  C  CB    . GLN   F 3 461 ? 16.747  84.546  -45.724 1.00 28.11  ? 754  GLN   D CB    1 
ATOM   9105  C  CG    . GLN   F 3 461 ? 17.103  85.905  -46.294 1.00 32.19  ? 754  GLN   D CG    1 
ATOM   9106  C  CD    . GLN   F 3 461 ? 16.042  86.497  -47.183 1.00 32.21  ? 754  GLN   D CD    1 
ATOM   9107  O  OE1   . GLN   F 3 461 ? 15.451  85.824  -48.027 1.00 35.86  ? 754  GLN   D OE1   1 
ATOM   9108  N  NE2   . GLN   F 3 461 ? 15.779  87.771  -46.962 1.00 30.52  ? 754  GLN   D NE2   1 
ATOM   9109  N  N     . GLY   F 3 462 ? 17.614  84.511  -42.667 1.00 26.00  ? 755  GLY   D N     1 
ATOM   9110  C  CA    . GLY   F 3 462 ? 17.867  85.214  -41.413 1.00 25.87  ? 755  GLY   D CA    1 
ATOM   9111  C  C     . GLY   F 3 462 ? 19.109  84.727  -40.675 1.00 24.18  ? 755  GLY   D C     1 
ATOM   9112  O  O     . GLY   F 3 462 ? 19.853  85.534  -40.113 1.00 28.35  ? 755  GLY   D O     1 
ATOM   9113  N  N     . THR   F 3 463 ? 19.333  83.412  -40.638 1.00 25.21  ? 756  THR   D N     1 
ATOM   9114  C  CA    . THR   F 3 463 ? 20.541  82.889  -40.006 1.00 25.40  ? 756  THR   D CA    1 
ATOM   9115  C  C     . THR   F 3 463 ? 21.776  83.431  -40.732 1.00 25.02  ? 756  THR   D C     1 
ATOM   9116  O  O     . THR   F 3 463 ? 22.727  83.870  -40.111 1.00 26.69  ? 756  THR   D O     1 
ATOM   9117  C  CB    . THR   F 3 463 ? 20.527  81.355  -39.956 1.00 25.41  ? 756  THR   D CB    1 
ATOM   9118  O  OG1   . THR   F 3 463 ? 19.489  80.902  -39.065 1.00 23.21  ? 756  THR   D OG1   1 
ATOM   9119  C  CG2   . THR   F 3 463 ? 21.884  80.824  -39.543 1.00 24.87  ? 756  THR   D CG2   1 
ATOM   9120  N  N     . ALA   F 3 464 ? 21.732  83.448  -42.067 1.00 26.98  ? 757  ALA   D N     1 
ATOM   9121  C  CA    . ALA   F 3 464 ? 22.810  83.987  -42.884 1.00 25.84  ? 757  ALA   D CA    1 
ATOM   9122  C  C     . ALA   F 3 464 ? 23.049  85.465  -42.584 1.00 25.06  ? 757  ALA   D C     1 
ATOM   9123  O  O     . ALA   F 3 464 ? 24.194  85.911  -42.525 1.00 31.16  ? 757  ALA   D O     1 
ATOM   9124  C  CB    . ALA   F 3 464 ? 22.498  83.762  -44.349 1.00 25.03  ? 757  ALA   D CB    1 
ATOM   9125  N  N     . ALA   F 3 465 ? 21.968  86.236  -42.425 1.00 26.71  ? 758  ALA   D N     1 
ATOM   9126  C  CA    . ALA   F 3 465 ? 22.071  87.652  -42.090 1.00 24.97  ? 758  ALA   D CA    1 
ATOM   9127  C  C     . ALA   F 3 465 ? 22.689  87.843  -40.703 1.00 26.29  ? 758  ALA   D C     1 
ATOM   9128  O  O     . ALA   F 3 465 ? 23.534  88.712  -40.511 1.00 28.71  ? 758  ALA   D O     1 
ATOM   9129  C  CB    . ALA   F 3 465 ? 20.706  88.279  -42.161 1.00 25.84  ? 758  ALA   D CB    1 
ATOM   9130  N  N     . ASP   F 3 466 ? 22.246  87.028  -39.741 1.00 26.19  ? 759  ASP   D N     1 
ATOM   9131  C  CA    . ASP   F 3 466 ? 22.760  87.069  -38.377 1.00 27.19  ? 759  ASP   D CA    1 
ATOM   9132  C  C     . ASP   F 3 466 ? 24.265  86.816  -38.370 1.00 25.93  ? 759  ASP   D C     1 
ATOM   9133  O  O     . ASP   F 3 466 ? 25.002  87.521  -37.691 1.00 27.91  ? 759  ASP   D O     1 
ATOM   9134  C  CB    . ASP   F 3 466 ? 22.046  86.037  -37.490 1.00 27.05  ? 759  ASP   D CB    1 
ATOM   9135  C  CG    . ASP   F 3 466 ? 20.588  86.323  -37.141 1.00 28.65  ? 759  ASP   D CG    1 
ATOM   9136  O  OD1   . ASP   F 3 466 ? 20.140  87.473  -37.319 1.00 33.07  ? 759  ASP   D OD1   1 
ATOM   9137  O  OD2   . ASP   F 3 466 ? 19.886  85.369  -36.702 1.00 31.79  ? 759  ASP   D OD2   1 
ATOM   9138  N  N     . LEU   F 3 467 ? 24.712  85.827  -39.152 1.00 27.85  ? 760  LEU   D N     1 
ATOM   9139  C  CA    . LEU   F 3 467 ? 26.119  85.440  -39.198 1.00 30.83  ? 760  LEU   D CA    1 
ATOM   9140  C  C     . LEU   F 3 467 ? 26.964  86.552  -39.815 1.00 30.45  ? 760  LEU   D C     1 
ATOM   9141  O  O     . LEU   F 3 467 ? 28.058  86.826  -39.341 1.00 30.32  ? 760  LEU   D O     1 
ATOM   9142  C  CB    . LEU   F 3 467 ? 26.275  84.148  -40.008 1.00 32.18  ? 760  LEU   D CB    1 
ATOM   9143  C  CG    . LEU   F 3 467 ? 25.795  82.854  -39.343 1.00 33.71  ? 760  LEU   D CG    1 
ATOM   9144  C  CD1   . LEU   F 3 467 ? 25.833  81.709  -40.359 1.00 32.75  ? 760  LEU   D CD1   1 
ATOM   9145  C  CD2   . LEU   F 3 467 ? 26.647  82.504  -38.133 1.00 31.36  ? 760  LEU   D CD2   1 
ATOM   9146  N  N     . MET   F 3 468 ? 26.456  87.185  -40.881 1.00 30.10  ? 761  MET   D N     1 
ATOM   9147  C  CA    . MET   F 3 468 ? 27.169  88.283  -41.512 1.00 29.17  ? 761  MET   D CA    1 
ATOM   9148  C  C     . MET   F 3 468 ? 27.306  89.459  -40.543 1.00 27.46  ? 761  MET   D C     1 
ATOM   9149  O  O     . MET   F 3 468 ? 28.366  90.081  -40.484 1.00 29.35  ? 761  MET   D O     1 
ATOM   9150  C  CB    . MET   F 3 468 ? 26.454  88.739  -42.799 1.00 28.26  ? 761  MET   D CB    1 
ATOM   9151  C  CG    . MET   F 3 468 ? 27.057  89.975  -43.454 1.00 25.69  ? 761  MET   D CG    1 
ATOM   9152  S  SD    . MET   F 3 468 ? 28.847  89.886  -43.732 1.00 27.54  ? 761  MET   D SD    1 
ATOM   9153  C  CE    . MET   F 3 468 ? 28.855  89.197  -45.377 1.00 29.81  ? 761  MET   D CE    1 
ATOM   9154  N  N     . LYS   F 3 469 ? 26.225  89.786  -39.818 1.00 27.60  ? 762  LYS   D N     1 
ATOM   9155  C  CA    . LYS   F 3 469 ? 26.213  90.912  -38.888 1.00 28.62  ? 762  LYS   D CA    1 
ATOM   9156  C  C     . LYS   F 3 469 ? 27.213  90.705  -37.750 1.00 27.96  ? 762  LYS   D C     1 
ATOM   9157  O  O     . LYS   F 3 469 ? 27.808  91.646  -37.249 1.00 31.42  ? 762  LYS   D O     1 
ATOM   9158  C  CB    . LYS   F 3 469 ? 24.822  91.115  -38.283 1.00 27.46  ? 762  LYS   D CB    1 
ATOM   9159  C  CG    . LYS   F 3 469 ? 23.778  91.720  -39.210 1.00 27.62  ? 762  LYS   D CG    1 
ATOM   9160  C  CD    . LYS   F 3 469 ? 22.397  91.791  -38.594 1.00 28.26  ? 762  LYS   D CD    1 
ATOM   9161  C  CE    . LYS   F 3 469 ? 21.466  92.616  -39.444 1.00 30.73  ? 762  LYS   D CE    1 
ATOM   9162  N  NZ    . LYS   F 3 469 ? 20.085  92.634  -38.912 1.00 32.60  ? 762  LYS   D NZ    1 
ATOM   9163  N  N     . LEU   F 3 470 ? 27.363  89.467  -37.313 1.00 30.68  ? 763  LEU   D N     1 
ATOM   9164  C  CA    . LEU   F 3 470 ? 28.284  89.120  -36.243 1.00 32.16  ? 763  LEU   D CA    1 
ATOM   9165  C  C     . LEU   F 3 470 ? 29.728  89.239  -36.745 1.00 31.93  ? 763  LEU   D C     1 
ATOM   9166  O  O     . LEU   F 3 470 ? 30.616  89.696  -36.024 1.00 32.13  ? 763  LEU   D O     1 
ATOM   9167  C  CB    . LEU   F 3 470 ? 27.884  87.698  -35.843 1.00 38.68  ? 763  LEU   D CB    1 
ATOM   9168  C  CG    . LEU   F 3 470 ? 28.387  87.137  -34.515 1.00 45.58  ? 763  LEU   D CG    1 
ATOM   9169  C  CD1   . LEU   F 3 470 ? 28.297  88.151  -33.373 1.00 49.58  ? 763  LEU   D CD1   1 
ATOM   9170  C  CD2   . LEU   F 3 470 ? 27.586  85.883  -34.204 1.00 46.31  ? 763  LEU   D CD2   1 
ATOM   9171  N  N     . ALA   F 3 471 ? 29.950  88.860  -38.013 1.00 28.23  ? 764  ALA   D N     1 
ATOM   9172  C  CA    . ALA   F 3 471 ? 31.226  89.038  -38.678 1.00 28.50  ? 764  ALA   D CA    1 
ATOM   9173  C  C     . ALA   F 3 471 ? 31.602  90.516  -38.774 1.00 30.38  ? 764  ALA   D C     1 
ATOM   9174  O  O     . ALA   F 3 471 ? 32.751  90.885  -38.496 1.00 31.82  ? 764  ALA   D O     1 
ATOM   9175  C  CB    . ALA   F 3 471 ? 31.163  88.412  -40.038 1.00 29.74  ? 764  ALA   D CB    1 
ATOM   9176  N  N     . MET   F 3 472 ? 30.637  91.359  -39.173 1.00 28.79  ? 765  MET   D N     1 
ATOM   9177  C  CA    . MET   F 3 472 ? 30.859  92.800  -39.276 1.00 28.16  ? 765  MET   D CA    1 
ATOM   9178  C  C     . MET   F 3 472 ? 31.237  93.398  -37.919 1.00 28.48  ? 765  MET   D C     1 
ATOM   9179  O  O     . MET   F 3 472 ? 32.186  94.177  -37.834 1.00 30.70  ? 765  MET   D O     1 
ATOM   9180  C  CB    . MET   F 3 472 ? 29.603  93.494  -39.816 1.00 26.66  ? 765  MET   D CB    1 
ATOM   9181  C  CG    . MET   F 3 472 ? 29.336  93.144  -41.247 1.00 26.47  ? 765  MET   D CG    1 
ATOM   9182  S  SD    . MET   F 3 472 ? 27.763  93.701  -41.867 1.00 29.57  ? 765  MET   D SD    1 
ATOM   9183  C  CE    . MET   F 3 472 ? 28.185  95.423  -42.152 1.00 30.16  ? 765  MET   D CE    1 
ATOM   9184  N  N     . VAL   F 3 473 ? 30.461  93.074  -36.872 1.00 31.47  ? 766  VAL   D N     1 
ATOM   9185  C  CA    . VAL   F 3 473 ? 30.662  93.620  -35.531 1.00 32.64  ? 766  VAL   D CA    1 
ATOM   9186  C  C     . VAL   F 3 473 ? 32.040  93.219  -34.994 1.00 33.91  ? 766  VAL   D C     1 
ATOM   9187  O  O     . VAL   F 3 473 ? 32.703  93.998  -34.304 1.00 38.21  ? 766  VAL   D O     1 
ATOM   9188  C  CB    . VAL   F 3 473 ? 29.539  93.130  -34.597 1.00 32.00  ? 766  VAL   D CB    1 
ATOM   9189  C  CG1   . VAL   F 3 473 ? 29.892  93.271  -33.119 1.00 33.37  ? 766  VAL   D CG1   1 
ATOM   9190  C  CG2   . VAL   F 3 473 ? 28.208  93.804  -34.911 1.00 30.19  ? 766  VAL   D CG2   1 
ATOM   9191  N  N     . LYS   F 3 474 ? 32.462  91.999  -35.327 1.00 33.54  ? 767  LYS   D N     1 
ATOM   9192  C  CA    . LYS   F 3 474 ? 33.745  91.453  -34.909 1.00 35.00  ? 767  LYS   D CA    1 
ATOM   9193  C  C     . LYS   F 3 474 ? 34.901  92.044  -35.724 1.00 33.56  ? 767  LYS   D C     1 
ATOM   9194  O  O     . LYS   F 3 474 ? 35.947  92.372  -35.174 1.00 36.11  ? 767  LYS   D O     1 
ATOM   9195  C  CB    . LYS   F 3 474 ? 33.687  89.928  -35.022 1.00 38.19  ? 767  LYS   D CB    1 
ATOM   9196  C  CG    . LYS   F 3 474 ? 34.833  89.218  -34.315 1.00 48.95  ? 767  LYS   D CG    1 
ATOM   9197  C  CD    . LYS   F 3 474 ? 35.010  87.736  -34.610 1.00 53.98  ? 767  LYS   D CD    1 
ATOM   9198  C  CE    . LYS   F 3 474 ? 34.246  86.813  -33.683 1.00 58.72  ? 767  LYS   D CE    1 
ATOM   9199  N  NZ    . LYS   F 3 474 ? 34.740  85.418  -33.811 1.00 57.17  ? 767  LYS   D NZ    1 
ATOM   9200  N  N     . LEU   F 3 475 ? 34.713  92.165  -37.037 1.00 32.07  ? 768  LEU   D N     1 
ATOM   9201  C  CA    . LEU   F 3 475 ? 35.739  92.630  -37.953 1.00 32.86  ? 768  LEU   D CA    1 
ATOM   9202  C  C     . LEU   F 3 475 ? 35.972  94.139  -37.857 1.00 33.26  ? 768  LEU   D C     1 
ATOM   9203  O  O     . LEU   F 3 475 ? 37.111  94.598  -37.928 1.00 36.39  ? 768  LEU   D O     1 
ATOM   9204  C  CB    . LEU   F 3 475 ? 35.302  92.252  -39.370 1.00 34.97  ? 768  LEU   D CB    1 
ATOM   9205  C  CG    . LEU   F 3 475 ? 36.283  92.605  -40.481 1.00 36.16  ? 768  LEU   D CG    1 
ATOM   9206  C  CD1   . LEU   F 3 475 ? 37.671  92.044  -40.181 1.00 38.17  ? 768  LEU   D CD1   1 
ATOM   9207  C  CD2   . LEU   F 3 475 ? 35.770  92.099  -41.817 1.00 34.93  ? 768  LEU   D CD2   1 
ATOM   9208  N  N     . PHE   F 3 476 ? 34.913  94.934  -37.729 1.00 32.01  ? 769  PHE   D N     1 
ATOM   9209  C  CA    . PHE   F 3 476 ? 35.070  96.363  -37.914 1.00 34.36  ? 769  PHE   D CA    1 
ATOM   9210  C  C     . PHE   F 3 476 ? 36.153  96.964  -37.010 1.00 37.12  ? 769  PHE   D C     1 
ATOM   9211  O  O     . PHE   F 3 476 ? 36.987  97.734  -37.498 1.00 42.23  ? 769  PHE   D O     1 
ATOM   9212  C  CB    . PHE   F 3 476 ? 33.764  97.120  -37.698 1.00 34.83  ? 769  PHE   D CB    1 
ATOM   9213  C  CG    . PHE   F 3 476 ? 33.912  98.596  -37.950 1.00 34.58  ? 769  PHE   D CG    1 
ATOM   9214  C  CD1   . PHE   F 3 476 ? 34.074  99.073  -39.242 1.00 38.45  ? 769  PHE   D CD1   1 
ATOM   9215  C  CD2   . PHE   F 3 476 ? 33.928  99.500  -36.902 1.00 36.64  ? 769  PHE   D CD2   1 
ATOM   9216  C  CE1   . PHE   F 3 476 ? 34.201  100.435 -39.484 1.00 41.00  ? 769  PHE   D CE1   1 
ATOM   9217  C  CE2   . PHE   F 3 476 ? 34.065  100.859 -37.144 1.00 37.85  ? 769  PHE   D CE2   1 
ATOM   9218  C  CZ    . PHE   F 3 476 ? 34.211  101.323 -38.429 1.00 36.54  ? 769  PHE   D CZ    1 
ATOM   9219  N  N     . PRO   F 3 477 ? 36.165  96.710  -35.681 1.00 37.96  ? 770  PRO   D N     1 
ATOM   9220  C  CA    . PRO   F 3 477 ? 37.150  97.347  -34.798 1.00 38.18  ? 770  PRO   D CA    1 
ATOM   9221  C  C     . PRO   F 3 477 ? 38.597  97.013  -35.160 1.00 37.80  ? 770  PRO   D C     1 
ATOM   9222  O  O     . PRO   F 3 477 ? 39.473  97.827  -34.922 1.00 45.48  ? 770  PRO   D O     1 
ATOM   9223  C  CB    . PRO   F 3 477 ? 36.839  96.807  -33.386 1.00 39.47  ? 770  PRO   D CB    1 
ATOM   9224  C  CG    . PRO   F 3 477 ? 35.460  96.143  -33.496 1.00 40.59  ? 770  PRO   D CG    1 
ATOM   9225  C  CD    . PRO   F 3 477 ? 35.265  95.800  -34.956 1.00 38.21  ? 770  PRO   D CD    1 
ATOM   9226  N  N     . ARG   F 3 478 ? 38.831  95.809  -35.706 1.00 42.48  ? 771  ARG   D N     1 
ATOM   9227  C  CA    . ARG   F 3 478 ? 40.146  95.364  -36.143 1.00 42.67  ? 771  ARG   D CA    1 
ATOM   9228  C  C     . ARG   F 3 478 ? 40.590  96.048  -37.435 1.00 42.64  ? 771  ARG   D C     1 
ATOM   9229  O  O     . ARG   F 3 478 ? 41.789  96.175  -37.670 1.00 47.31  ? 771  ARG   D O     1 
ATOM   9230  C  CB    . ARG   F 3 478 ? 40.159  93.855  -36.413 1.00 44.37  ? 771  ARG   D CB    1 
ATOM   9231  C  CG    . ARG   F 3 478 ? 39.812  92.984  -35.217 1.00 46.21  ? 771  ARG   D CG    1 
ATOM   9232  C  CD    . ARG   F 3 478 ? 40.616  93.310  -33.965 1.00 46.64  ? 771  ARG   D CD    1 
ATOM   9233  N  NE    . ARG   F 3 478 ? 39.695  93.226  -32.846 1.00 52.56  ? 771  ARG   D NE    1 
ATOM   9234  C  CZ    . ARG   F 3 478 ? 39.277  94.249  -32.110 1.00 47.48  ? 771  ARG   D CZ    1 
ATOM   9235  N  NH1   . ARG   F 3 478 ? 38.195  94.109  -31.367 1.00 44.34  ? 771  ARG   D NH1   1 
ATOM   9236  N  NH2   . ARG   F 3 478 ? 39.979  95.365  -32.056 1.00 47.56  ? 771  ARG   D NH2   1 
ATOM   9237  N  N     . LEU   F 3 479 ? 39.642  96.438  -38.300 1.00 43.90  ? 772  LEU   D N     1 
ATOM   9238  C  CA    . LEU   F 3 479 ? 39.978  97.157  -39.520 1.00 43.24  ? 772  LEU   D CA    1 
ATOM   9239  C  C     . LEU   F 3 479 ? 40.536  98.534  -39.170 1.00 45.97  ? 772  LEU   D C     1 
ATOM   9240  O  O     . LEU   F 3 479 ? 41.526  98.956  -39.760 1.00 46.38  ? 772  LEU   D O     1 
ATOM   9241  C  CB    . LEU   F 3 479 ? 38.743  97.305  -40.413 1.00 42.87  ? 772  LEU   D CB    1 
ATOM   9242  C  CG    . LEU   F 3 479 ? 38.199  96.024  -41.032 1.00 39.03  ? 772  LEU   D CG    1 
ATOM   9243  C  CD1   . LEU   F 3 479 ? 37.078  96.338  -42.003 1.00 40.26  ? 772  LEU   D CD1   1 
ATOM   9244  C  CD2   . LEU   F 3 479 ? 39.295  95.227  -41.718 1.00 38.54  ? 772  LEU   D CD2   1 
ATOM   9245  N  N     . GLU   F 3 480 ? 39.909  99.226  -38.210 1.00 54.33  ? 773  GLU   D N     1 
ATOM   9246  C  CA    . GLU   F 3 480 ? 40.318  100.583 -37.853 1.00 65.99  ? 773  GLU   D CA    1 
ATOM   9247  C  C     . GLU   F 3 480 ? 41.771  100.624 -37.370 1.00 63.34  ? 773  GLU   D C     1 
ATOM   9248  O  O     . GLU   F 3 480 ? 42.519  101.528 -37.728 1.00 60.87  ? 773  GLU   D O     1 
ATOM   9249  C  CB    . GLU   F 3 480 ? 39.401  101.163 -36.776 1.00 71.87  ? 773  GLU   D CB    1 
ATOM   9250  C  CG    . GLU   F 3 480 ? 37.997  101.473 -37.259 1.00 71.25  ? 773  GLU   D CG    1 
ATOM   9251  C  CD    . GLU   F 3 480 ? 37.170  102.204 -36.213 1.00 78.37  ? 773  GLU   D CD    1 
ATOM   9252  O  OE1   . GLU   F 3 480 ? 37.163  101.746 -35.044 1.00 71.20  ? 773  GLU   D OE1   1 
ATOM   9253  O  OE2   . GLU   F 3 480 ? 36.534  103.227 -36.564 1.00 83.60  ? 773  GLU   D OE2   1 
ATOM   9254  N  N     . GLU   F 3 481 ? 42.165  99.621  -36.578 1.00 65.90  ? 774  GLU   D N     1 
ATOM   9255  C  CA    . GLU   F 3 481 ? 43.519  99.501  -36.058 1.00 63.88  ? 774  GLU   D CA    1 
ATOM   9256  C  C     . GLU   F 3 481 ? 44.530  99.395  -37.198 1.00 57.50  ? 774  GLU   D C     1 
ATOM   9257  O  O     . GLU   F 3 481 ? 45.702  99.669  -36.999 1.00 60.51  ? 774  GLU   D O     1 
ATOM   9258  C  CB    . GLU   F 3 481 ? 43.611  98.264  -35.155 1.00 69.68  ? 774  GLU   D CB    1 
ATOM   9259  C  CG    . GLU   F 3 481 ? 42.773  98.369  -33.879 1.00 71.57  ? 774  GLU   D CG    1 
ATOM   9260  C  CD    . GLU   F 3 481 ? 42.583  97.085  -33.075 1.00 74.43  ? 774  GLU   D CD    1 
ATOM   9261  O  OE1   . GLU   F 3 481 ? 42.950  95.984  -33.575 1.00 62.15  ? 774  GLU   D OE1   1 
ATOM   9262  O  OE2   . GLU   F 3 481 ? 42.052  97.184  -31.942 1.00 73.29  ? 774  GLU   D OE2   1 
ATOM   9263  N  N     . MET   F 3 482 ? 44.085  98.944  -38.376 1.00 61.34  ? 775  MET   D N     1 
ATOM   9264  C  CA    . MET   F 3 482 ? 44.966  98.654  -39.500 1.00 55.26  ? 775  MET   D CA    1 
ATOM   9265  C  C     . MET   F 3 482 ? 44.860  99.746  -40.565 1.00 52.68  ? 775  MET   D C     1 
ATOM   9266  O  O     . MET   F 3 482 ? 45.394  99.567  -41.653 1.00 50.47  ? 775  MET   D O     1 
ATOM   9267  C  CB    . MET   F 3 482 ? 44.582  97.326  -40.163 1.00 58.09  ? 775  MET   D CB    1 
ATOM   9268  C  CG    . MET   F 3 482 ? 44.837  96.104  -39.314 1.00 65.22  ? 775  MET   D CG    1 
ATOM   9269  S  SD    . MET   F 3 482 ? 44.457  94.570  -40.220 1.00 69.83  ? 775  MET   D SD    1 
ATOM   9270  C  CE    . MET   F 3 482 ? 45.990  94.343  -41.118 1.00 67.57  ? 775  MET   D CE    1 
ATOM   9271  N  N     . GLY   F 3 483 ? 44.154  100.852 -40.264 1.00 54.68  ? 776  GLY   D N     1 
ATOM   9272  C  CA    . GLY   F 3 483 ? 43.905  101.920 -41.230 1.00 52.22  ? 776  GLY   D CA    1 
ATOM   9273  C  C     . GLY   F 3 483 ? 43.103  101.457 -42.454 1.00 51.76  ? 776  GLY   D C     1 
ATOM   9274  O  O     . GLY   F 3 483 ? 43.369  101.893 -43.573 1.00 52.29  ? 776  GLY   D O     1 
ATOM   9275  N  N     . ALA   F 3 484 ? 42.112  100.580 -42.231 1.00 45.31  ? 777  ALA   D N     1 
ATOM   9276  C  CA    . ALA   F 3 484 ? 41.261  100.068 -43.294 1.00 41.55  ? 777  ALA   D CA    1 
ATOM   9277  C  C     . ALA   F 3 484 ? 39.817  100.480 -43.036 1.00 40.09  ? 777  ALA   D C     1 
ATOM   9278  O  O     . ALA   F 3 484 ? 39.467  100.931 -41.937 1.00 39.88  ? 777  ALA   D O     1 
ATOM   9279  C  CB    . ALA   F 3 484 ? 41.378  98.572  -43.414 1.00 43.42  ? 777  ALA   D CB    1 
ATOM   9280  N  N     . ARG   F 3 485 ? 39.001  100.365 -44.091 1.00 35.03  ? 778  ARG   D N     1 
ATOM   9281  C  CA    . ARG   F 3 485 ? 37.629  100.829 -44.047 1.00 36.75  ? 778  ARG   D CA    1 
ATOM   9282  C  C     . ARG   F 3 485 ? 36.707  99.721  -44.522 1.00 35.75  ? 778  ARG   D C     1 
ATOM   9283  O  O     . ARG   F 3 485 ? 37.086  98.910  -45.359 1.00 33.23  ? 778  ARG   D O     1 
ATOM   9284  C  CB    . ARG   F 3 485 ? 37.412  102.028 -44.973 1.00 38.61  ? 778  ARG   D CB    1 
ATOM   9285  C  CG    . ARG   F 3 485 ? 38.251  103.259 -44.655 1.00 40.93  ? 778  ARG   D CG    1 
ATOM   9286  C  CD    . ARG   F 3 485 ? 38.307  104.148 -45.879 1.00 41.78  ? 778  ARG   D CD    1 
ATOM   9287  N  NE    . ARG   F 3 485 ? 39.197  105.287 -45.729 1.00 45.35  ? 778  ARG   D NE    1 
ATOM   9288  C  CZ    . ARG   F 3 485 ? 39.600  106.062 -46.732 1.00 46.54  ? 778  ARG   D CZ    1 
ATOM   9289  N  NH1   . ARG   F 3 485 ? 39.305  105.767 -47.988 1.00 43.02  ? 778  ARG   D NH1   1 
ATOM   9290  N  NH2   . ARG   F 3 485 ? 40.310  107.141 -46.470 1.00 50.64  ? 778  ARG   D NH2   1 
ATOM   9291  N  N     . MET   F 3 486 ? 35.483  99.764  -44.002 1.00 36.16  ? 779  MET   D N     1 
ATOM   9292  C  CA    . MET   F 3 486 ? 34.380  98.943  -44.463 1.00 34.74  ? 779  MET   D CA    1 
ATOM   9293  C  C     . MET   F 3 486 ? 33.459  99.838  -45.282 1.00 34.81  ? 779  MET   D C     1 
ATOM   9294  O  O     . MET   F 3 486 ? 32.945  100.824 -44.753 1.00 34.71  ? 779  MET   D O     1 
ATOM   9295  C  CB    . MET   F 3 486 ? 33.627  98.360  -43.258 1.00 34.40  ? 779  MET   D CB    1 
ATOM   9296  C  CG    . MET   F 3 486 ? 32.682  97.216  -43.605 1.00 38.84  ? 779  MET   D CG    1 
ATOM   9297  S  SD    . MET   F 3 486 ? 32.010  96.334  -42.144 1.00 40.93  ? 779  MET   D SD    1 
ATOM   9298  C  CE    . MET   F 3 486 ? 33.494  95.512  -41.570 1.00 40.42  ? 779  MET   D CE    1 
ATOM   9299  N  N     . LEU   F 3 487 ? 33.262  99.509  -46.569 1.00 33.68  ? 780  LEU   D N     1 
ATOM   9300  C  CA    . LEU   F 3 487 ? 32.486  100.378 -47.443 1.00 34.49  ? 780  LEU   D CA    1 
ATOM   9301  C  C     . LEU   F 3 487 ? 31.060  99.852  -47.622 1.00 33.18  ? 780  LEU   D C     1 
ATOM   9302  O  O     . LEU   F 3 487 ? 30.104  100.635 -47.523 1.00 32.95  ? 780  LEU   D O     1 
ATOM   9303  C  CB    . LEU   F 3 487 ? 33.183  100.499 -48.803 1.00 34.84  ? 780  LEU   D CB    1 
ATOM   9304  C  CG    . LEU   F 3 487 ? 34.625  101.008 -48.801 1.00 35.12  ? 780  LEU   D CG    1 
ATOM   9305  C  CD1   . LEU   F 3 487 ? 35.027  101.397 -50.213 1.00 36.40  ? 780  LEU   D CD1   1 
ATOM   9306  C  CD2   . LEU   F 3 487 ? 34.823  102.176 -47.840 1.00 35.68  ? 780  LEU   D CD2   1 
ATOM   9307  N  N     . LEU   F 3 488 ? 30.927  98.555  -47.960 1.00 32.51  ? 781  LEU   D N     1 
ATOM   9308  C  CA    . LEU   F 3 488 ? 29.639  97.995  -48.357 1.00 31.71  ? 781  LEU   D CA    1 
ATOM   9309  C  C     . LEU   F 3 488 ? 29.431  96.601  -47.776 1.00 32.06  ? 781  LEU   D C     1 
ATOM   9310  O  O     . LEU   F 3 488 ? 30.385  95.861  -47.542 1.00 31.09  ? 781  LEU   D O     1 
ATOM   9311  C  CB    . LEU   F 3 488 ? 29.552  97.910  -49.881 1.00 32.21  ? 781  LEU   D CB    1 
ATOM   9312  C  CG    . LEU   F 3 488 ? 29.777  99.210  -50.647 1.00 32.78  ? 781  LEU   D CG    1 
ATOM   9313  C  CD1   . LEU   F 3 488 ? 29.910  98.917  -52.132 1.00 35.17  ? 781  LEU   D CD1   1 
ATOM   9314  C  CD2   . LEU   F 3 488 ? 28.654  100.204 -50.411 1.00 35.08  ? 781  LEU   D CD2   1 
ATOM   9315  N  N     . GLN   F 3 489 ? 28.145  96.279  -47.570 1.00 32.22  ? 782  GLN   D N     1 
ATOM   9316  C  CA    . GLN   F 3 489 ? 27.661  94.928  -47.363 1.00 31.17  ? 782  GLN   D CA    1 
ATOM   9317  C  C     . GLN   F 3 489 ? 26.621  94.667  -48.440 1.00 29.79  ? 782  GLN   D C     1 
ATOM   9318  O  O     . GLN   F 3 489 ? 25.787  95.527  -48.716 1.00 30.22  ? 782  GLN   D O     1 
ATOM   9319  C  CB    . GLN   F 3 489 ? 27.116  94.758  -45.938 1.00 32.95  ? 782  GLN   D CB    1 
ATOM   9320  C  CG    . GLN   F 3 489 ? 26.682  93.330  -45.588 1.00 33.23  ? 782  GLN   D CG    1 
ATOM   9321  C  CD    . GLN   F 3 489 ? 25.181  93.173  -45.503 1.00 32.38  ? 782  GLN   D CD    1 
ATOM   9322  O  OE1   . GLN   F 3 489 ? 24.442  93.610  -46.381 1.00 35.01  ? 782  GLN   D OE1   1 
ATOM   9323  N  NE2   . GLN   F 3 489 ? 24.715  92.569  -44.425 1.00 30.94  ? 782  GLN   D NE2   1 
ATOM   9324  N  N     . VAL   F 3 490 ? 26.714  93.489  -49.074 1.00 29.28  ? 783  VAL   D N     1 
ATOM   9325  C  CA    . VAL   F 3 490 ? 25.730  93.083  -50.069 1.00 27.26  ? 783  VAL   D CA    1 
ATOM   9326  C  C     . VAL   F 3 490 ? 25.293  91.666  -49.712 1.00 26.14  ? 783  VAL   D C     1 
ATOM   9327  O  O     . VAL   F 3 490 ? 25.530  90.690  -50.429 1.00 27.78  ? 783  VAL   D O     1 
ATOM   9328  C  CB    . VAL   F 3 490 ? 26.253  93.246  -51.509 1.00 27.37  ? 783  VAL   D CB    1 
ATOM   9329  C  CG1   . VAL   F 3 490 ? 25.156  92.992  -52.520 1.00 27.04  ? 783  VAL   D CG1   1 
ATOM   9330  C  CG2   . VAL   F 3 490 ? 26.868  94.629  -51.733 1.00 27.25  ? 783  VAL   D CG2   1 
ATOM   9331  N  N     . HIS   F 3 491 ? 24.716  91.612  -48.511 1.00 26.29  ? 784  HIS   D N     1 
ATOM   9332  C  CA    . HIS   F 3 491 ? 24.099  90.445  -47.922 1.00 28.52  ? 784  HIS   D CA    1 
ATOM   9333  C  C     . HIS   F 3 491 ? 25.147  89.438  -47.466 1.00 27.46  ? 784  HIS   D C     1 
ATOM   9334  O  O     . HIS   F 3 491 ? 25.455  89.387  -46.291 1.00 33.66  ? 784  HIS   D O     1 
ATOM   9335  C  CB    . HIS   F 3 491 ? 23.052  89.899  -48.876 1.00 26.36  ? 784  HIS   D CB    1 
ATOM   9336  C  CG    . HIS   F 3 491 ? 22.038  90.938  -49.211 1.00 25.83  ? 784  HIS   D CG    1 
ATOM   9337  N  ND1   . HIS   F 3 491 ? 21.358  91.654  -48.261 1.00 24.81  ? 784  HIS   D ND1   1 
ATOM   9338  C  CD2   . HIS   F 3 491 ? 21.692  91.431  -50.443 1.00 25.78  ? 784  HIS   D CD2   1 
ATOM   9339  C  CE1   . HIS   F 3 491 ? 20.555  92.511  -48.889 1.00 26.72  ? 784  HIS   D CE1   1 
ATOM   9340  N  NE2   . HIS   F 3 491 ? 20.752  92.392  -50.249 1.00 23.53  ? 784  HIS   D NE2   1 
ATOM   9341  N  N     . ASP   F 3 492 ? 25.674  88.627  -48.370 1.00 29.98  ? 785  ASP   D N     1 
ATOM   9342  C  CA    . ASP   F 3 492 ? 26.714  87.681  -47.999 1.00 30.95  ? 785  ASP   D CA    1 
ATOM   9343  C  C     . ASP   F 3 492 ? 28.091  88.184  -48.438 1.00 30.06  ? 785  ASP   D C     1 
ATOM   9344  O  O     . ASP   F 3 492 ? 29.045  87.428  -48.413 1.00 28.87  ? 785  ASP   D O     1 
ATOM   9345  C  CB    . ASP   F 3 492 ? 26.395  86.295  -48.569 1.00 30.39  ? 785  ASP   D CB    1 
ATOM   9346  C  CG    . ASP   F 3 492 ? 26.500  86.151  -50.074 1.00 30.04  ? 785  ASP   D CG    1 
ATOM   9347  O  OD1   . ASP   F 3 492 ? 26.421  87.199  -50.771 1.00 28.63  ? 785  ASP   D OD1   1 
ATOM   9348  O  OD2   . ASP   F 3 492 ? 26.660  84.969  -50.540 1.00 26.15  ? 785  ASP   D OD2   1 
ATOM   9349  N  N     . GLU   F 3 493 ? 28.199  89.482  -48.759 1.00 32.99  ? 786  GLU   D N     1 
ATOM   9350  C  CA    . GLU   F 3 493 ? 29.416  90.065  -49.301 1.00 33.03  ? 786  GLU   D CA    1 
ATOM   9351  C  C     . GLU   F 3 493 ? 29.778  91.323  -48.514 1.00 29.02  ? 786  GLU   D C     1 
ATOM   9352  O  O     . GLU   F 3 493 ? 28.888  92.068  -48.141 1.00 28.46  ? 786  GLU   D O     1 
ATOM   9353  C  CB    . GLU   F 3 493 ? 29.174  90.367  -50.780 1.00 36.97  ? 786  GLU   D CB    1 
ATOM   9354  C  CG    . GLU   F 3 493 ? 30.299  91.127  -51.434 1.00 41.89  ? 786  GLU   D CG    1 
ATOM   9355  C  CD    . GLU   F 3 493 ? 30.133  91.463  -52.913 1.00 45.04  ? 786  GLU   D CD    1 
ATOM   9356  O  OE1   . GLU   F 3 493 ? 29.024  91.193  -53.511 1.00 41.47  ? 786  GLU   D OE1   1 
ATOM   9357  O  OE2   . GLU   F 3 493 ? 31.138  91.976  -53.475 1.00 38.74  ? 786  GLU   D OE2   1 
ATOM   9358  N  N     . LEU   F 3 494 ? 31.084  91.509  -48.259 1.00 28.91  ? 787  LEU   D N     1 
ATOM   9359  C  CA    . LEU   F 3 494 ? 31.675  92.700  -47.675 1.00 30.16  ? 787  LEU   D CA    1 
ATOM   9360  C  C     . LEU   F 3 494 ? 32.687  93.286  -48.662 1.00 30.97  ? 787  LEU   D C     1 
ATOM   9361  O  O     . LEU   F 3 494 ? 33.462  92.542  -49.278 1.00 31.01  ? 787  LEU   D O     1 
ATOM   9362  C  CB    . LEU   F 3 494 ? 32.379  92.340  -46.353 1.00 32.86  ? 787  LEU   D CB    1 
ATOM   9363  C  CG    . LEU   F 3 494 ? 31.479  92.173  -45.133 1.00 33.39  ? 787  LEU   D CG    1 
ATOM   9364  C  CD1   . LEU   F 3 494 ? 32.294  91.903  -43.884 1.00 35.67  ? 787  LEU   D CD1   1 
ATOM   9365  C  CD2   . LEU   F 3 494 ? 30.615  93.401  -44.933 1.00 34.87  ? 787  LEU   D CD2   1 
ATOM   9366  N  N     . VAL   F 3 495 ? 32.637  94.622  -48.832 1.00 30.81  ? 788  VAL   D N     1 
ATOM   9367  C  CA    . VAL   F 3 495 ? 33.630  95.371  -49.597 1.00 31.13  ? 788  VAL   D CA    1 
ATOM   9368  C  C     . VAL   F 3 495 ? 34.360  96.291  -48.627 1.00 32.47  ? 788  VAL   D C     1 
ATOM   9369  O  O     . VAL   F 3 495 ? 33.732  97.065  -47.889 1.00 32.57  ? 788  VAL   D O     1 
ATOM   9370  C  CB    . VAL   F 3 495 ? 33.028  96.162  -50.778 1.00 31.45  ? 788  VAL   D CB    1 
ATOM   9371  C  CG1   . VAL   F 3 495 ? 34.112  96.799  -51.629 1.00 32.33  ? 788  VAL   D CG1   1 
ATOM   9372  C  CG2   . VAL   F 3 495 ? 32.117  95.299  -51.649 1.00 30.04  ? 788  VAL   D CG2   1 
ATOM   9373  N  N     . LEU   F 3 496 ? 35.689  96.131  -48.593 1.00 32.91  ? 789  LEU   D N     1 
ATOM   9374  C  CA    . LEU   F 3 496 ? 36.549  96.929  -47.740 1.00 34.67  ? 789  LEU   D CA    1 
ATOM   9375  C  C     . LEU   F 3 496 ? 37.466  97.776  -48.612 1.00 33.00  ? 789  LEU   D C     1 
ATOM   9376  O  O     . LEU   F 3 496 ? 37.633  97.490  -49.789 1.00 36.61  ? 789  LEU   D O     1 
ATOM   9377  C  CB    . LEU   F 3 496 ? 37.379  96.000  -46.854 1.00 37.68  ? 789  LEU   D CB    1 
ATOM   9378  C  CG    . LEU   F 3 496 ? 36.623  94.842  -46.205 1.00 41.35  ? 789  LEU   D CG    1 
ATOM   9379  C  CD1   . LEU   F 3 496 ? 37.596  93.977  -45.422 1.00 43.33  ? 789  LEU   D CD1   1 
ATOM   9380  C  CD2   . LEU   F 3 496 ? 35.507  95.345  -45.300 1.00 38.38  ? 789  LEU   D CD2   1 
ATOM   9381  N  N     . GLU   F 3 497 ? 38.089  98.786  -47.996 1.00 35.84  ? 790  GLU   D N     1 
ATOM   9382  C  CA    . GLU   F 3 497 ? 39.109  99.593  -48.639 1.00 36.03  ? 790  GLU   D CA    1 
ATOM   9383  C  C     . GLU   F 3 497 ? 40.318  99.647  -47.712 1.00 38.61  ? 790  GLU   D C     1 
ATOM   9384  O  O     . GLU   F 3 497 ? 40.175  99.952  -46.528 1.00 38.78  ? 790  GLU   D O     1 
ATOM   9385  C  CB    . GLU   F 3 497 ? 38.584  101.008 -48.891 1.00 36.83  ? 790  GLU   D CB    1 
ATOM   9386  C  CG    . GLU   F 3 497 ? 39.217  101.751 -50.059 1.00 35.60  ? 790  GLU   D CG    1 
ATOM   9387  C  CD    . GLU   F 3 497 ? 38.652  103.161 -50.208 1.00 41.54  ? 790  GLU   D CD    1 
ATOM   9388  O  OE1   . GLU   F 3 497 ? 38.120  103.680 -49.192 1.00 40.29  ? 790  GLU   D OE1   1 
ATOM   9389  O  OE2   . GLU   F 3 497 ? 38.676  103.726 -51.334 1.00 38.31  ? 790  GLU   D OE2   1 
ATOM   9390  N  N     . ALA   F 3 498 ? 41.506  99.378  -48.271 1.00 38.48  ? 791  ALA   D N     1 
ATOM   9391  C  CA    . ALA   F 3 498 ? 42.729  99.369  -47.483 1.00 38.95  ? 791  ALA   D CA    1 
ATOM   9392  C  C     . ALA   F 3 498 ? 43.859  100.009 -48.282 1.00 37.74  ? 791  ALA   D C     1 
ATOM   9393  O  O     . ALA   F 3 498 ? 43.862  99.929  -49.512 1.00 34.99  ? 791  ALA   D O     1 
ATOM   9394  C  CB    . ALA   F 3 498 ? 43.089  97.954  -47.103 1.00 38.60  ? 791  ALA   D CB    1 
ATOM   9395  N  N     . PRO   F 3 499 ? 44.862  100.625 -47.613 1.00 40.37  ? 792  PRO   D N     1 
ATOM   9396  C  CA    . PRO   F 3 499 ? 46.080  101.072 -48.304 1.00 43.43  ? 792  PRO   D CA    1 
ATOM   9397  C  C     . PRO   F 3 499 ? 46.709  99.877  -49.021 1.00 45.11  ? 792  PRO   D C     1 
ATOM   9398  O  O     . PRO   F 3 499 ? 46.703  98.787  -48.462 1.00 44.03  ? 792  PRO   D O     1 
ATOM   9399  C  CB    . PRO   F 3 499 ? 46.952  101.647 -47.175 1.00 39.57  ? 792  PRO   D CB    1 
ATOM   9400  C  CG    . PRO   F 3 499 ? 45.967  101.983 -46.054 1.00 40.39  ? 792  PRO   D CG    1 
ATOM   9401  C  CD    . PRO   F 3 499 ? 44.885  100.923 -46.165 1.00 40.15  ? 792  PRO   D CD    1 
ATOM   9402  N  N     . LYS   F 3 500 ? 47.191  100.085 -50.264 1.00 48.17  ? 793  LYS   D N     1 
ATOM   9403  C  CA    . LYS   F 3 500 ? 47.761  99.047  -51.122 1.00 53.14  ? 793  LYS   D CA    1 
ATOM   9404  C  C     . LYS   F 3 500 ? 48.775  98.190  -50.357 1.00 58.70  ? 793  LYS   D C     1 
ATOM   9405  O  O     . LYS   F 3 500 ? 48.904  96.999  -50.614 1.00 63.44  ? 793  LYS   D O     1 
ATOM   9406  C  CB    . LYS   F 3 500 ? 48.413  99.672  -52.365 1.00 48.60  ? 793  LYS   D CB    1 
ATOM   9407  N  N     . GLU   F 3 501 ? 49.487  98.821  -49.415 1.00 61.28  ? 794  GLU   D N     1 
ATOM   9408  C  CA    . GLU   F 3 501 ? 50.496  98.206  -48.561 1.00 67.09  ? 794  GLU   D CA    1 
ATOM   9409  C  C     . GLU   F 3 501 ? 49.861  97.146  -47.654 1.00 65.96  ? 794  GLU   D C     1 
ATOM   9410  O  O     . GLU   F 3 501 ? 50.404  96.058  -47.492 1.00 59.41  ? 794  GLU   D O     1 
ATOM   9411  C  CB    . GLU   F 3 501 ? 51.154  99.286  -47.683 1.00 76.72  ? 794  GLU   D CB    1 
ATOM   9412  C  CG    . GLU   F 3 501 ? 50.969  100.728 -48.187 1.00 81.27  ? 794  GLU   D CG    1 
ATOM   9413  C  CD    . GLU   F 3 501 ? 50.755  101.781 -47.113 1.00 89.66  ? 794  GLU   D CD    1 
ATOM   9414  O  OE1   . GLU   F 3 501 ? 50.000  101.524 -46.150 1.00 82.40  ? 794  GLU   D OE1   1 
ATOM   9415  O  OE2   . GLU   F 3 501 ? 51.332  102.870 -47.256 1.00 109.73 ? 794  GLU   D OE2   1 
ATOM   9416  N  N     . ARG   F 3 502 ? 48.707  97.486  -47.056 1.00 61.47  ? 795  ARG   D N     1 
ATOM   9417  C  CA    . ARG   F 3 502 ? 48.081  96.702  -46.003 1.00 56.12  ? 795  ARG   D CA    1 
ATOM   9418  C  C     . ARG   F 3 502 ? 47.006  95.762  -46.549 1.00 52.98  ? 795  ARG   D C     1 
ATOM   9419  O  O     . ARG   F 3 502 ? 46.372  95.048  -45.772 1.00 57.03  ? 795  ARG   D O     1 
ATOM   9420  C  CB    . ARG   F 3 502 ? 47.421  97.620  -44.962 1.00 64.69  ? 795  ARG   D CB    1 
ATOM   9421  C  CG    . ARG   F 3 502 ? 48.319  98.673  -44.318 1.00 70.88  ? 795  ARG   D CG    1 
ATOM   9422  C  CD    . ARG   F 3 502 ? 49.504  98.105  -43.548 1.00 77.53  ? 795  ARG   D CD    1 
ATOM   9423  N  NE    . ARG   F 3 502 ? 49.122  97.318  -42.381 1.00 83.04  ? 795  ARG   D NE    1 
ATOM   9424  C  CZ    . ARG   F 3 502 ? 48.905  97.818  -41.164 1.00 84.58  ? 795  ARG   D CZ    1 
ATOM   9425  N  NH1   . ARG   F 3 502 ? 48.962  99.124  -40.954 1.00 80.05  ? 795  ARG   D NH1   1 
ATOM   9426  N  NH2   . ARG   F 3 502 ? 48.624  97.002  -40.162 1.00 80.08  ? 795  ARG   D NH2   1 
ATOM   9427  N  N     . ALA   F 3 503 ? 46.798  95.734  -47.871 1.00 51.12  ? 796  ALA   D N     1 
ATOM   9428  C  CA    . ALA   F 3 503 ? 45.616  95.100  -48.448 1.00 49.18  ? 796  ALA   D CA    1 
ATOM   9429  C  C     . ALA   F 3 503 ? 45.657  93.577  -48.315 1.00 51.77  ? 796  ALA   D C     1 
ATOM   9430  O  O     . ALA   F 3 503 ? 44.605  92.941  -48.202 1.00 49.70  ? 796  ALA   D O     1 
ATOM   9431  C  CB    . ALA   F 3 503 ? 45.449  95.511  -49.897 1.00 45.00  ? 796  ALA   D CB    1 
ATOM   9432  N  N     . GLU   F 3 504 ? 46.859  92.987  -48.359 1.00 58.10  ? 797  GLU   D N     1 
ATOM   9433  C  CA    . GLU   F 3 504 ? 47.018  91.536  -48.264 1.00 58.64  ? 797  GLU   D CA    1 
ATOM   9434  C  C     . GLU   F 3 504 ? 46.654  91.064  -46.860 1.00 49.65  ? 797  GLU   D C     1 
ATOM   9435  O  O     . GLU   F 3 504 ? 45.981  90.049  -46.709 1.00 47.18  ? 797  GLU   D O     1 
ATOM   9436  C  CB    . GLU   F 3 504 ? 48.458  91.095  -48.554 1.00 63.54  ? 797  GLU   D CB    1 
ATOM   9437  C  CG    . GLU   F 3 504 ? 48.895  91.285  -49.996 1.00 70.48  ? 797  GLU   D CG    1 
ATOM   9438  C  CD    . GLU   F 3 504 ? 48.221  90.362  -50.995 1.00 72.88  ? 797  GLU   D CD    1 
ATOM   9439  O  OE1   . GLU   F 3 504 ? 47.555  89.389  -50.558 1.00 72.90  ? 797  GLU   D OE1   1 
ATOM   9440  O  OE2   . GLU   F 3 504 ? 48.351  90.630  -52.208 1.00 78.36  ? 797  GLU   D OE2   1 
ATOM   9441  N  N     . ALA   F 3 505 ? 47.127  91.825  -45.864 1.00 45.30  ? 798  ALA   D N     1 
ATOM   9442  C  CA    . ALA   F 3 505 ? 46.913  91.538  -44.455 1.00 50.60  ? 798  ALA   D CA    1 
ATOM   9443  C  C     . ALA   F 3 505 ? 45.450  91.758  -44.056 1.00 49.47  ? 798  ALA   D C     1 
ATOM   9444  O  O     . ALA   F 3 505 ? 44.939  91.039  -43.194 1.00 45.01  ? 798  ALA   D O     1 
ATOM   9445  C  CB    . ALA   F 3 505 ? 47.831  92.407  -43.625 1.00 48.41  ? 798  ALA   D CB    1 
ATOM   9446  N  N     . VAL   F 3 506 ? 44.815  92.782  -44.656 1.00 45.72  ? 799  VAL   D N     1 
ATOM   9447  C  CA    . VAL   F 3 506 ? 43.419  93.100  -44.403 1.00 43.19  ? 799  VAL   D CA    1 
ATOM   9448  C  C     . VAL   F 3 506 ? 42.575  91.969  -44.977 1.00 44.15  ? 799  VAL   D C     1 
ATOM   9449  O  O     . VAL   F 3 506 ? 41.638  91.512  -44.331 1.00 43.34  ? 799  VAL   D O     1 
ATOM   9450  C  CB    . VAL   F 3 506 ? 43.018  94.475  -44.975 1.00 41.62  ? 799  VAL   D CB    1 
ATOM   9451  C  CG1   . VAL   F 3 506 ? 41.510  94.659  -45.048 1.00 44.34  ? 799  VAL   D CG1   1 
ATOM   9452  C  CG2   . VAL   F 3 506 ? 43.635  95.623  -44.191 1.00 40.87  ? 799  VAL   D CG2   1 
ATOM   9453  N  N     . ALA   F 3 507 ? 42.949  91.474  -46.162 1.00 44.29  ? 800  ALA   D N     1 
ATOM   9454  C  CA    . ALA   F 3 507 ? 42.203  90.380  -46.767 1.00 46.29  ? 800  ALA   D CA    1 
ATOM   9455  C  C     . ALA   F 3 507 ? 42.262  89.143  -45.874 1.00 48.67  ? 800  ALA   D C     1 
ATOM   9456  O  O     . ALA   F 3 507 ? 41.246  88.492  -45.671 1.00 46.38  ? 800  ALA   D O     1 
ATOM   9457  C  CB    . ALA   F 3 507 ? 42.711  90.075  -48.154 1.00 45.03  ? 800  ALA   D CB    1 
ATOM   9458  N  N     . ARG   F 3 508 ? 43.458  88.829  -45.355 1.00 52.97  ? 801  ARG   D N     1 
ATOM   9459  C  CA    . ARG   F 3 508 ? 43.689  87.622  -44.574 1.00 56.66  ? 801  ARG   D CA    1 
ATOM   9460  C  C     . ARG   F 3 508 ? 42.898  87.671  -43.257 1.00 51.33  ? 801  ARG   D C     1 
ATOM   9461  O  O     . ARG   F 3 508 ? 42.228  86.712  -42.888 1.00 47.52  ? 801  ARG   D O     1 
ATOM   9462  C  CB    . ARG   F 3 508 ? 45.204  87.441  -44.393 1.00 63.69  ? 801  ARG   D CB    1 
ATOM   9463  C  CG    . ARG   F 3 508 ? 45.632  86.380  -43.384 1.00 76.21  ? 801  ARG   D CG    1 
ATOM   9464  C  CD    . ARG   F 3 508 ? 47.048  85.874  -43.651 1.00 88.69  ? 801  ARG   D CD    1 
ATOM   9465  N  NE    . ARG   F 3 508 ? 47.986  86.929  -44.053 1.00 94.05  ? 801  ARG   D NE    1 
ATOM   9466  C  CZ    . ARG   F 3 508 ? 48.539  87.052  -45.262 1.00 90.54  ? 801  ARG   D CZ    1 
ATOM   9467  N  NH1   . ARG   F 3 508 ? 48.480  86.055  -46.130 1.00 90.73  ? 801  ARG   D NH1   1 
ATOM   9468  N  NH2   . ARG   F 3 508 ? 49.158  88.176  -45.596 1.00 81.72  ? 801  ARG   D NH2   1 
ATOM   9469  N  N     . LEU   F 3 509 ? 42.957  88.798  -42.550 1.00 47.22  ? 802  LEU   D N     1 
ATOM   9470  C  CA    . LEU   F 3 509 ? 42.201  88.979  -41.323 1.00 47.78  ? 802  LEU   D CA    1 
ATOM   9471  C  C     . LEU   F 3 509 ? 40.693  88.888  -41.562 1.00 49.05  ? 802  LEU   D C     1 
ATOM   9472  O  O     . LEU   F 3 509 ? 39.992  88.266  -40.768 1.00 53.30  ? 802  LEU   D O     1 
ATOM   9473  C  CB    . LEU   F 3 509 ? 42.556  90.340  -40.737 1.00 51.49  ? 802  LEU   D CB    1 
ATOM   9474  C  CG    . LEU   F 3 509 ? 41.804  90.685  -39.456 1.00 57.94  ? 802  LEU   D CG    1 
ATOM   9475  C  CD1   . LEU   F 3 509 ? 42.373  89.913  -38.272 1.00 59.42  ? 802  LEU   D CD1   1 
ATOM   9476  C  CD2   . LEU   F 3 509 ? 41.844  92.181  -39.216 1.00 59.97  ? 802  LEU   D CD2   1 
ATOM   9477  N  N     . ALA   F 3 510 ? 40.191  89.533  -42.628 1.00 42.58  ? 803  ALA   D N     1 
ATOM   9478  C  CA    . ALA   F 3 510 ? 38.763  89.552  -42.901 1.00 41.57  ? 803  ALA   D CA    1 
ATOM   9479  C  C     . ALA   F 3 510 ? 38.254  88.142  -43.192 1.00 38.57  ? 803  ALA   D C     1 
ATOM   9480  O  O     . ALA   F 3 510 ? 37.206  87.752  -42.692 1.00 48.10  ? 803  ALA   D O     1 
ATOM   9481  C  CB    . ALA   F 3 510 ? 38.457  90.499  -44.037 1.00 40.56  ? 803  ALA   D CB    1 
ATOM   9482  N  N     . LYS   F 3 511 ? 38.991  87.399  -44.015 1.00 40.09  ? 804  LYS   D N     1 
ATOM   9483  C  CA    . LYS   F 3 511 ? 38.732  85.987  -44.293 1.00 43.45  ? 804  LYS   D CA    1 
ATOM   9484  C  C     . LYS   F 3 511 ? 38.659  85.157  -43.002 1.00 41.94  ? 804  LYS   D C     1 
ATOM   9485  O  O     . LYS   F 3 511 ? 37.699  84.426  -42.803 1.00 41.20  ? 804  LYS   D O     1 
ATOM   9486  C  CB    . LYS   F 3 511 ? 39.835  85.420  -45.196 1.00 42.16  ? 804  LYS   D CB    1 
ATOM   9487  C  CG    . LYS   F 3 511 ? 39.523  84.097  -45.889 1.00 45.83  ? 804  LYS   D CG    1 
ATOM   9488  C  CD    . LYS   F 3 511 ? 40.769  83.382  -46.414 1.00 48.25  ? 804  LYS   D CD    1 
ATOM   9489  C  CE    . LYS   F 3 511 ? 40.519  82.482  -47.605 1.00 51.41  ? 804  LYS   D CE    1 
ATOM   9490  N  NZ    . LYS   F 3 511 ? 39.687  81.302  -47.276 1.00 52.58  ? 804  LYS   D NZ    1 
ATOM   9491  N  N     . GLU   F 3 512 ? 39.685  85.228  -42.145 1.00 41.65  ? 805  GLU   D N     1 
ATOM   9492  C  CA    . GLU   F 3 512 ? 39.696  84.490  -40.885 1.00 49.03  ? 805  GLU   D CA    1 
ATOM   9493  C  C     . GLU   F 3 512 ? 38.424  84.781  -40.078 1.00 47.00  ? 805  GLU   D C     1 
ATOM   9494  O  O     . GLU   F 3 512 ? 37.727  83.856  -39.660 1.00 47.57  ? 805  GLU   D O     1 
ATOM   9495  C  CB    . GLU   F 3 512 ? 40.930  84.841  -40.040 1.00 51.73  ? 805  GLU   D CB    1 
ATOM   9496  C  CG    . GLU   F 3 512 ? 42.227  84.285  -40.596 1.00 62.13  ? 805  GLU   D CG    1 
ATOM   9497  C  CD    . GLU   F 3 512 ? 43.494  84.608  -39.813 1.00 74.84  ? 805  GLU   D CD    1 
ATOM   9498  O  OE1   . GLU   F 3 512 ? 44.267  83.661  -39.537 1.00 84.36  ? 805  GLU   D OE1   1 
ATOM   9499  O  OE2   . GLU   F 3 512 ? 43.717  85.799  -39.487 1.00 79.25  ? 805  GLU   D OE2   1 
ATOM   9500  N  N     . VAL   F 3 513 ? 38.141  86.071  -39.844 1.00 43.18  ? 806  VAL   D N     1 
ATOM   9501  C  CA    . VAL   F 3 513 ? 37.036  86.485  -38.988 1.00 41.28  ? 806  VAL   D CA    1 
ATOM   9502  C  C     . VAL   F 3 513 ? 35.712  85.991  -39.563 1.00 39.94  ? 806  VAL   D C     1 
ATOM   9503  O  O     . VAL   F 3 513 ? 34.859  85.495  -38.841 1.00 45.90  ? 806  VAL   D O     1 
ATOM   9504  C  CB    . VAL   F 3 513 ? 37.038  88.015  -38.799 1.00 40.12  ? 806  VAL   D CB    1 
ATOM   9505  C  CG1   . VAL   F 3 513 ? 35.760  88.526  -38.154 1.00 38.40  ? 806  VAL   D CG1   1 
ATOM   9506  C  CG2   . VAL   F 3 513 ? 38.253  88.463  -37.998 1.00 38.66  ? 806  VAL   D CG2   1 
ATOM   9507  N  N     . MET   F 3 514 ? 35.546  86.108  -40.880 1.00 40.70  ? 807  MET   D N     1 
ATOM   9508  C  CA    . MET   F 3 514 ? 34.270  85.813  -41.503 1.00 38.18  ? 807  MET   D CA    1 
ATOM   9509  C  C     . MET   F 3 514 ? 33.974  84.312  -41.487 1.00 40.57  ? 807  MET   D C     1 
ATOM   9510  O  O     . MET   F 3 514 ? 32.809  83.913  -41.521 1.00 41.72  ? 807  MET   D O     1 
ATOM   9511  C  CB    . MET   F 3 514 ? 34.256  86.334  -42.941 1.00 37.13  ? 807  MET   D CB    1 
ATOM   9512  C  CG    . MET   F 3 514 ? 33.964  87.822  -43.034 1.00 40.76  ? 807  MET   D CG    1 
ATOM   9513  S  SD    . MET   F 3 514 ? 34.094  88.441  -44.724 1.00 37.30  ? 807  MET   D SD    1 
ATOM   9514  C  CE    . MET   F 3 514 ? 32.599  87.786  -45.459 1.00 34.80  ? 807  MET   D CE    1 
ATOM   9515  N  N     . GLU   F 3 515 ? 35.019  83.480  -41.460 1.00 44.71  ? 808  GLU   D N     1 
ATOM   9516  C  CA    . GLU   F 3 515 ? 34.876  82.029  -41.565 1.00 46.91  ? 808  GLU   D CA    1 
ATOM   9517  C  C     . GLU   F 3 515 ? 34.821  81.373  -40.183 1.00 43.42  ? 808  GLU   D C     1 
ATOM   9518  O  O     . GLU   F 3 515 ? 34.440  80.216  -40.075 1.00 46.92  ? 808  GLU   D O     1 
ATOM   9519  C  CB    . GLU   F 3 515 ? 36.057  81.428  -42.335 1.00 47.45  ? 808  GLU   D CB    1 
ATOM   9520  C  CG    . GLU   F 3 515 ? 36.116  81.840  -43.794 1.00 47.75  ? 808  GLU   D CG    1 
ATOM   9521  C  CD    . GLU   F 3 515 ? 37.203  81.167  -44.610 1.00 43.74  ? 808  GLU   D CD    1 
ATOM   9522  O  OE1   . GLU   F 3 515 ? 38.240  80.788  -44.023 1.00 45.56  ? 808  GLU   D OE1   1 
ATOM   9523  O  OE2   . GLU   F 3 515 ? 37.007  81.025  -45.830 1.00 39.81  ? 808  GLU   D OE2   1 
ATOM   9524  N  N     . GLY   F 3 516 ? 35.220  82.103  -39.138 1.00 44.29  ? 809  GLY   D N     1 
ATOM   9525  C  CA    . GLY   F 3 516 ? 35.265  81.546  -37.797 1.00 47.47  ? 809  GLY   D CA    1 
ATOM   9526  C  C     . GLY   F 3 516 ? 34.169  82.070  -36.865 1.00 44.44  ? 809  GLY   D C     1 
ATOM   9527  O  O     . GLY   F 3 516 ? 34.360  82.021  -35.651 1.00 47.42  ? 809  GLY   D O     1 
ATOM   9528  N  N     . VAL   F 3 517 ? 33.027  82.521  -37.411 1.00 42.04  ? 810  VAL   D N     1 
ATOM   9529  C  CA    . VAL   F 3 517 ? 32.045  83.267  -36.621 1.00 40.54  ? 810  VAL   D CA    1 
ATOM   9530  C  C     . VAL   F 3 517 ? 31.229  82.321  -35.744 1.00 35.63  ? 810  VAL   D C     1 
ATOM   9531  O  O     . VAL   F 3 517 ? 30.799  82.745  -34.685 1.00 39.66  ? 810  VAL   D O     1 
ATOM   9532  C  CB    . VAL   F 3 517 ? 31.089  84.195  -37.430 1.00 39.88  ? 810  VAL   D CB    1 
ATOM   9533  C  CG1   . VAL   F 3 517 ? 31.719  85.535  -37.770 1.00 40.16  ? 810  VAL   D CG1   1 
ATOM   9534  C  CG2   . VAL   F 3 517 ? 30.500  83.551  -38.668 1.00 40.44  ? 810  VAL   D CG2   1 
ATOM   9535  N  N     . TYR   F 3 518 ? 30.982  81.076  -36.181 1.00 37.24  ? 811  TYR   D N     1 
ATOM   9536  C  CA    . TYR   F 3 518 ? 30.108  80.175  -35.443 1.00 36.49  ? 811  TYR   D CA    1 
ATOM   9537  C  C     . TYR   F 3 518 ? 30.437  78.721  -35.744 1.00 35.85  ? 811  TYR   D C     1 
ATOM   9538  O  O     . TYR   F 3 518 ? 30.829  78.373  -36.858 1.00 34.58  ? 811  TYR   D O     1 
ATOM   9539  C  CB    . TYR   F 3 518 ? 28.642  80.464  -35.761 1.00 41.33  ? 811  TYR   D CB    1 
ATOM   9540  C  CG    . TYR   F 3 518 ? 27.632  79.835  -34.829 1.00 47.11  ? 811  TYR   D CG    1 
ATOM   9541  C  CD1   . TYR   F 3 518 ? 27.187  78.533  -35.019 1.00 47.19  ? 811  TYR   D CD1   1 
ATOM   9542  C  CD2   . TYR   F 3 518 ? 27.120  80.537  -33.745 1.00 46.97  ? 811  TYR   D CD2   1 
ATOM   9543  C  CE1   . TYR   F 3 518 ? 26.250  77.955  -34.175 1.00 48.26  ? 811  TYR   D CE1   1 
ATOM   9544  C  CE2   . TYR   F 3 518 ? 26.164  79.983  -32.904 1.00 50.40  ? 811  TYR   D CE2   1 
ATOM   9545  C  CZ    . TYR   F 3 518 ? 25.734  78.684  -33.119 1.00 49.08  ? 811  TYR   D CZ    1 
ATOM   9546  O  OH    . TYR   F 3 518 ? 24.811  78.106  -32.292 1.00 62.04  ? 811  TYR   D OH    1 
ATOM   9547  N  N     . PRO   F 3 519 ? 30.324  77.827  -34.734 1.00 35.97  ? 812  PRO   D N     1 
ATOM   9548  C  CA    . PRO   F 3 519 ? 30.549  76.393  -34.940 1.00 37.41  ? 812  PRO   D CA    1 
ATOM   9549  C  C     . PRO   F 3 519 ? 29.425  75.678  -35.696 1.00 41.22  ? 812  PRO   D C     1 
ATOM   9550  O  O     . PRO   F 3 519 ? 28.583  74.964  -35.120 1.00 43.76  ? 812  PRO   D O     1 
ATOM   9551  C  CB    . PRO   F 3 519 ? 30.697  75.847  -33.512 1.00 35.93  ? 812  PRO   D CB    1 
ATOM   9552  C  CG    . PRO   F 3 519 ? 29.900  76.819  -32.661 1.00 38.30  ? 812  PRO   D CG    1 
ATOM   9553  C  CD    . PRO   F 3 519 ? 30.081  78.168  -33.325 1.00 35.89  ? 812  PRO   D CD    1 
ATOM   9554  N  N     . LEU   F 3 520 ? 29.469  75.819  -37.023 1.00 37.37  ? 813  LEU   D N     1 
ATOM   9555  C  CA    . LEU   F 3 520 ? 28.485  75.179  -37.874 1.00 39.39  ? 813  LEU   D CA    1 
ATOM   9556  C  C     . LEU   F 3 520 ? 28.923  73.757  -38.201 1.00 40.05  ? 813  LEU   D C     1 
ATOM   9557  O  O     . LEU   F 3 520 ? 30.088  73.411  -38.053 1.00 43.49  ? 813  LEU   D O     1 
ATOM   9558  C  CB    . LEU   F 3 520 ? 28.345  75.999  -39.155 1.00 40.13  ? 813  LEU   D CB    1 
ATOM   9559  C  CG    . LEU   F 3 520 ? 27.826  77.420  -38.964 1.00 38.69  ? 813  LEU   D CG    1 
ATOM   9560  C  CD1   . LEU   F 3 520 ? 27.747  78.125  -40.309 1.00 40.32  ? 813  LEU   D CD1   1 
ATOM   9561  C  CD2   . LEU   F 3 520 ? 26.463  77.421  -38.289 1.00 41.11  ? 813  LEU   D CD2   1 
ATOM   9562  N  N     . ALA   F 3 521 ? 27.965  72.975  -38.701 1.00 41.27  ? 814  ALA   D N     1 
ATOM   9563  C  CA    . ALA   F 3 521 ? 28.197  71.599  -39.105 1.00 42.12  ? 814  ALA   D CA    1 
ATOM   9564  C  C     . ALA   F 3 521 ? 28.850  71.580  -40.482 1.00 40.97  ? 814  ALA   D C     1 
ATOM   9565  O  O     . ALA   F 3 521 ? 29.279  70.518  -40.935 1.00 41.49  ? 814  ALA   D O     1 
ATOM   9566  C  CB    . ALA   F 3 521 ? 26.889  70.844  -39.096 1.00 40.24  ? 814  ALA   D CB    1 
ATOM   9567  N  N     . VAL   F 3 522 ? 28.877  72.757  -41.134 1.00 40.25  ? 815  VAL   D N     1 
ATOM   9568  C  CA    . VAL   F 3 522 ? 29.509  72.961  -42.428 1.00 42.43  ? 815  VAL   D CA    1 
ATOM   9569  C  C     . VAL   F 3 522 ? 30.528  74.093  -42.293 1.00 39.06  ? 815  VAL   D C     1 
ATOM   9570  O  O     . VAL   F 3 522 ? 30.267  75.103  -41.671 1.00 38.12  ? 815  VAL   D O     1 
ATOM   9571  C  CB    . VAL   F 3 522 ? 28.461  73.257  -43.525 1.00 47.48  ? 815  VAL   D CB    1 
ATOM   9572  C  CG1   . VAL   F 3 522 ? 29.091  73.683  -44.841 1.00 53.89  ? 815  VAL   D CG1   1 
ATOM   9573  C  CG2   . VAL   F 3 522 ? 27.580  72.054  -43.800 1.00 53.11  ? 815  VAL   D CG2   1 
ATOM   9574  N  N     . PRO   F 3 523 ? 31.731  73.996  -42.886 1.00 45.72  ? 816  PRO   D N     1 
ATOM   9575  C  CA    . PRO   F 3 523 ? 32.681  75.110  -42.823 1.00 45.67  ? 816  PRO   D CA    1 
ATOM   9576  C  C     . PRO   F 3 523 ? 32.148  76.263  -43.677 1.00 44.02  ? 816  PRO   D C     1 
ATOM   9577  O  O     . PRO   F 3 523 ? 31.559  76.033  -44.728 1.00 38.35  ? 816  PRO   D O     1 
ATOM   9578  C  CB    . PRO   F 3 523 ? 33.964  74.503  -43.412 1.00 46.10  ? 816  PRO   D CB    1 
ATOM   9579  C  CG    . PRO   F 3 523 ? 33.437  73.462  -44.407 1.00 47.22  ? 816  PRO   D CG    1 
ATOM   9580  C  CD    . PRO   F 3 523 ? 32.202  72.882  -43.742 1.00 47.55  ? 816  PRO   D CD    1 
ATOM   9581  N  N     . LEU   F 3 524 ? 32.295  77.489  -43.172 1.00 42.73  ? 817  LEU   D N     1 
ATOM   9582  C  CA    . LEU   F 3 524 ? 32.058  78.692  -43.943 1.00 46.04  ? 817  LEU   D CA    1 
ATOM   9583  C  C     . LEU   F 3 524 ? 33.320  79.036  -44.728 1.00 48.99  ? 817  LEU   D C     1 
ATOM   9584  O  O     . LEU   F 3 524 ? 34.393  79.160  -44.143 1.00 52.43  ? 817  LEU   D O     1 
ATOM   9585  C  CB    . LEU   F 3 524 ? 31.745  79.835  -42.979 1.00 47.08  ? 817  LEU   D CB    1 
ATOM   9586  C  CG    . LEU   F 3 524 ? 30.396  79.780  -42.290 1.00 46.28  ? 817  LEU   D CG    1 
ATOM   9587  C  CD1   . LEU   F 3 524 ? 30.257  80.970  -41.359 1.00 47.41  ? 817  LEU   D CD1   1 
ATOM   9588  C  CD2   . LEU   F 3 524 ? 29.266  79.745  -43.310 1.00 48.12  ? 817  LEU   D CD2   1 
ATOM   9589  N  N     . GLU   F 3 525 ? 33.169  79.245  -46.039 1.00 49.16  ? 818  GLU   D N     1 
ATOM   9590  C  CA    . GLU   F 3 525 ? 34.283  79.582  -46.912 1.00 50.18  ? 818  GLU   D CA    1 
ATOM   9591  C  C     . GLU   F 3 525 ? 34.009  80.949  -47.550 1.00 47.56  ? 818  GLU   D C     1 
ATOM   9592  O  O     . GLU   F 3 525 ? 32.896  81.236  -47.963 1.00 38.41  ? 818  GLU   D O     1 
ATOM   9593  C  CB    . GLU   F 3 525 ? 34.441  78.435  -47.910 1.00 57.53  ? 818  GLU   D CB    1 
ATOM   9594  C  CG    . GLU   F 3 525 ? 35.607  78.507  -48.881 1.00 66.05  ? 818  GLU   D CG    1 
ATOM   9595  C  CD    . GLU   F 3 525 ? 35.572  77.328  -49.845 1.00 66.51  ? 818  GLU   D CD    1 
ATOM   9596  O  OE1   . GLU   F 3 525 ? 35.566  76.178  -49.362 1.00 76.72  ? 818  GLU   D OE1   1 
ATOM   9597  O  OE2   . GLU   F 3 525 ? 35.491  77.551  -51.064 1.00 62.49  ? 818  GLU   D OE2   1 
ATOM   9598  N  N     . VAL   F 3 526 ? 35.052  81.777  -47.629 1.00 46.62  ? 819  VAL   D N     1 
ATOM   9599  C  CA    . VAL   F 3 526 ? 34.986  83.123  -48.177 1.00 50.14  ? 819  VAL   D CA    1 
ATOM   9600  C  C     . VAL   F 3 526 ? 35.884  83.226  -49.422 1.00 47.46  ? 819  VAL   D C     1 
ATOM   9601  O  O     . VAL   F 3 526 ? 37.073  82.928  -49.363 1.00 40.53  ? 819  VAL   D O     1 
ATOM   9602  C  CB    . VAL   F 3 526 ? 35.359  84.115  -47.052 1.00 50.86  ? 819  VAL   D CB    1 
ATOM   9603  C  CG1   . VAL   F 3 526 ? 35.997  85.398  -47.548 1.00 50.52  ? 819  VAL   D CG1   1 
ATOM   9604  C  CG2   . VAL   F 3 526 ? 34.147  84.417  -46.179 1.00 53.16  ? 819  VAL   D CG2   1 
ATOM   9605  N  N     . GLU   F 3 527 ? 35.288  83.623  -50.558 1.00 48.07  ? 820  GLU   D N     1 
ATOM   9606  C  CA    . GLU   F 3 527 ? 36.009  84.041  -51.753 1.00 52.43  ? 820  GLU   D CA    1 
ATOM   9607  C  C     . GLU   F 3 527 ? 36.525  85.475  -51.584 1.00 51.41  ? 820  GLU   D C     1 
ATOM   9608  O  O     . GLU   F 3 527 ? 35.725  86.406  -51.584 1.00 50.75  ? 820  GLU   D O     1 
ATOM   9609  C  CB    . GLU   F 3 527 ? 35.067  84.013  -52.965 1.00 57.37  ? 820  GLU   D CB    1 
ATOM   9610  C  CG    . GLU   F 3 527 ? 34.778  82.643  -53.541 1.00 66.45  ? 820  GLU   D CG    1 
ATOM   9611  C  CD    . GLU   F 3 527 ? 35.775  82.158  -54.582 1.00 74.39  ? 820  GLU   D CD    1 
ATOM   9612  O  OE1   . GLU   F 3 527 ? 36.096  82.944  -55.513 1.00 80.07  ? 820  GLU   D OE1   1 
ATOM   9613  O  OE2   . GLU   F 3 527 ? 36.215  80.994  -54.467 1.00 74.16  ? 820  GLU   D OE2   1 
ATOM   9614  N  N     . VAL   F 3 528 ? 37.851  85.643  -51.474 1.00 46.37  ? 821  VAL   D N     1 
ATOM   9615  C  CA    . VAL   F 3 528 ? 38.511  86.940  -51.383 1.00 45.82  ? 821  VAL   D CA    1 
ATOM   9616  C  C     . VAL   F 3 528 ? 39.084  87.371  -52.739 1.00 47.54  ? 821  VAL   D C     1 
ATOM   9617  O  O     . VAL   F 3 528 ? 39.630  86.550  -53.478 1.00 47.81  ? 821  VAL   D O     1 
ATOM   9618  C  CB    . VAL   F 3 528 ? 39.665  86.906  -50.367 1.00 45.75  ? 821  VAL   D CB    1 
ATOM   9619  C  CG1   . VAL   F 3 528 ? 39.939  88.293  -49.813 1.00 47.44  ? 821  VAL   D CG1   1 
ATOM   9620  C  CG2   . VAL   F 3 528 ? 39.413  85.921  -49.244 1.00 50.18  ? 821  VAL   D CG2   1 
ATOM   9621  N  N     . GLY   F 3 529 ? 39.010  88.684  -53.021 1.00 48.36  ? 822  GLY   D N     1 
ATOM   9622  C  CA    . GLY   F 3 529 ? 39.703  89.316  -54.141 1.00 42.39  ? 822  GLY   D CA    1 
ATOM   9623  C  C     . GLY   F 3 529 ? 40.179  90.733  -53.803 1.00 45.25  ? 822  GLY   D C     1 
ATOM   9624  O  O     . GLY   F 3 529 ? 39.569  91.443  -53.004 1.00 43.21  ? 822  GLY   D O     1 
ATOM   9625  N  N     . ILE   F 3 530 ? 41.311  91.134  -54.394 1.00 45.66  ? 823  ILE   D N     1 
ATOM   9626  C  CA    . ILE   F 3 530 ? 41.851  92.476  -54.232 1.00 47.04  ? 823  ILE   D CA    1 
ATOM   9627  C  C     . ILE   F 3 530 ? 41.948  93.116  -55.616 1.00 46.18  ? 823  ILE   D C     1 
ATOM   9628  O  O     . ILE   F 3 530 ? 42.292  92.448  -56.584 1.00 47.04  ? 823  ILE   D O     1 
ATOM   9629  C  CB    . ILE   F 3 530 ? 43.218  92.444  -53.516 1.00 47.95  ? 823  ILE   D CB    1 
ATOM   9630  C  CG1   . ILE   F 3 530 ? 43.165  91.607  -52.234 1.00 46.81  ? 823  ILE   D CG1   1 
ATOM   9631  C  CG2   . ILE   F 3 530 ? 43.718  93.855  -53.243 1.00 47.47  ? 823  ILE   D CG2   1 
ATOM   9632  C  CD1   . ILE   F 3 530 ? 44.460  91.591  -51.448 1.00 45.04  ? 823  ILE   D CD1   1 
ATOM   9633  N  N     . GLY   F 3 531 ? 41.645  94.412  -55.709 1.00 44.06  ? 824  GLY   D N     1 
ATOM   9634  C  CA    . GLY   F 3 531 ? 41.647  95.086  -56.995 1.00 42.70  ? 824  GLY   D CA    1 
ATOM   9635  C  C     . GLY   F 3 531 ? 41.450  96.592  -56.850 1.00 45.69  ? 824  GLY   D C     1 
ATOM   9636  O  O     . GLY   F 3 531 ? 41.065  97.080  -55.787 1.00 44.08  ? 824  GLY   D O     1 
ATOM   9637  N  N     . GLU   F 3 532 ? 41.700  97.317  -57.948 1.00 49.55  ? 825  GLU   D N     1 
ATOM   9638  C  CA    . GLU   F 3 532 ? 41.583  98.771  -57.960 1.00 52.34  ? 825  GLU   D CA    1 
ATOM   9639  C  C     . GLU   F 3 532 ? 40.116  99.165  -58.118 1.00 47.75  ? 825  GLU   D C     1 
ATOM   9640  O  O     . GLU   F 3 532 ? 39.729  100.278 -57.773 1.00 43.85  ? 825  GLU   D O     1 
ATOM   9641  C  CB    . GLU   F 3 532 ? 42.439  99.375  -59.080 1.00 53.57  ? 825  GLU   D CB    1 
ATOM   9642  C  CG    . GLU   F 3 532 ? 43.910  99.058  -58.934 1.00 62.20  ? 825  GLU   D CG    1 
ATOM   9643  C  CD    . GLU   F 3 532 ? 44.843  99.796  -59.875 1.00 70.79  ? 825  GLU   D CD    1 
ATOM   9644  O  OE1   . GLU   F 3 532 ? 44.654  99.680  -61.115 1.00 77.03  ? 825  GLU   D OE1   1 
ATOM   9645  O  OE2   . GLU   F 3 532 ? 45.775  100.460 -59.361 1.00 73.49  ? 825  GLU   D OE2   1 
ATOM   9646  N  N     . ASP   F 3 533 ? 39.319  98.241  -58.660 1.00 42.54  ? 826  ASP   D N     1 
ATOM   9647  C  CA    . ASP   F 3 533 ? 37.900  98.464  -58.846 1.00 42.07  ? 826  ASP   D CA    1 
ATOM   9648  C  C     . ASP   F 3 533 ? 37.146  97.203  -58.446 1.00 40.23  ? 826  ASP   D C     1 
ATOM   9649  O  O     . ASP   F 3 533 ? 37.752  96.158  -58.211 1.00 41.01  ? 826  ASP   D O     1 
ATOM   9650  C  CB    . ASP   F 3 533 ? 37.611  98.874  -60.288 1.00 42.62  ? 826  ASP   D CB    1 
ATOM   9651  C  CG    . ASP   F 3 533 ? 37.939  97.811  -61.314 1.00 46.57  ? 826  ASP   D CG    1 
ATOM   9652  O  OD1   . ASP   F 3 533 ? 37.163  96.844  -61.420 1.00 49.49  ? 826  ASP   D OD1   1 
ATOM   9653  O  OD2   . ASP   F 3 533 ? 38.983  97.956  -62.000 1.00 55.10  ? 826  ASP   D OD2   1 
ATOM   9654  N  N     . TRP   F 3 534 ? 35.818  97.315  -58.402 1.00 37.54  ? 827  TRP   D N     1 
ATOM   9655  C  CA    . TRP   F 3 534 ? 34.973  96.306  -57.792 1.00 39.72  ? 827  TRP   D CA    1 
ATOM   9656  C  C     . TRP   F 3 534 ? 34.889  95.067  -58.676 1.00 42.51  ? 827  TRP   D C     1 
ATOM   9657  O  O     . TRP   F 3 534 ? 34.700  93.956  -58.172 1.00 37.76  ? 827  TRP   D O     1 
ATOM   9658  C  CB    . TRP   F 3 534 ? 33.587  96.897  -57.505 1.00 38.90  ? 827  TRP   D CB    1 
ATOM   9659  C  CG    . TRP   F 3 534 ? 32.725  96.100  -56.579 1.00 36.49  ? 827  TRP   D CG    1 
ATOM   9660  C  CD1   . TRP   F 3 534 ? 32.990  94.879  -56.032 1.00 35.87  ? 827  TRP   D CD1   1 
ATOM   9661  C  CD2   . TRP   F 3 534 ? 31.410  96.465  -56.116 1.00 37.71  ? 827  TRP   D CD2   1 
ATOM   9662  N  NE1   . TRP   F 3 534 ? 31.937  94.466  -55.256 1.00 37.24  ? 827  TRP   D NE1   1 
ATOM   9663  C  CE2   . TRP   F 3 534 ? 30.960  95.426  -55.270 1.00 35.27  ? 827  TRP   D CE2   1 
ATOM   9664  C  CE3   . TRP   F 3 534 ? 30.569  97.557  -56.337 1.00 34.63  ? 827  TRP   D CE3   1 
ATOM   9665  C  CZ2   . TRP   F 3 534 ? 29.712  95.450  -54.651 1.00 34.98  ? 827  TRP   D CZ2   1 
ATOM   9666  C  CZ3   . TRP   F 3 534 ? 29.343  97.592  -55.703 1.00 37.45  ? 827  TRP   D CZ3   1 
ATOM   9667  C  CH2   . TRP   F 3 534 ? 28.916  96.546  -54.884 1.00 37.53  ? 827  TRP   D CH2   1 
ATOM   9668  N  N     . LEU   F 3 535 ? 35.000  95.255  -59.999 1.00 46.30  ? 828  LEU   D N     1 
ATOM   9669  C  CA    . LEU   F 3 535 ? 34.980  94.112  -60.898 1.00 44.87  ? 828  LEU   D CA    1 
ATOM   9670  C  C     . LEU   F 3 535 ? 36.248  93.292  -60.693 1.00 43.98  ? 828  LEU   D C     1 
ATOM   9671  O  O     . LEU   F 3 535 ? 36.174  92.073  -60.556 1.00 44.40  ? 828  LEU   D O     1 
ATOM   9672  C  CB    . LEU   F 3 535 ? 34.845  94.560  -62.359 1.00 47.26  ? 828  LEU   D CB    1 
ATOM   9673  C  CG    . LEU   F 3 535 ? 34.731  93.412  -63.369 1.00 50.68  ? 828  LEU   D CG    1 
ATOM   9674  C  CD1   . LEU   F 3 535 ? 33.380  92.695  -63.260 1.00 51.34  ? 828  LEU   D CD1   1 
ATOM   9675  C  CD2   . LEU   F 3 535 ? 34.960  93.904  -64.795 1.00 53.41  ? 828  LEU   D CD2   1 
ATOM   9676  N  N     . SER   F 3 536 ? 37.407  93.959  -60.697 1.00 40.81  ? 829  SER   D N     1 
ATOM   9677  C  CA    . SER   F 3 536 ? 38.665  93.234  -60.662 1.00 47.54  ? 829  SER   D CA    1 
ATOM   9678  C  C     . SER   F 3 536 ? 38.888  92.605  -59.281 1.00 48.67  ? 829  SER   D C     1 
ATOM   9679  O  O     . SER   F 3 536 ? 39.541  91.568  -59.165 1.00 45.66  ? 829  SER   D O     1 
ATOM   9680  C  CB    . SER   F 3 536 ? 39.814  94.102  -61.098 1.00 42.69  ? 829  SER   D CB    1 
ATOM   9681  O  OG    . SER   F 3 536 ? 39.858  95.275  -60.328 1.00 47.71  ? 829  SER   D OG    1 
ATOM   9682  N  N     . ALA   F 3 537 ? 38.286  93.185  -58.237 1.00 46.78  ? 830  ALA   D N     1 
ATOM   9683  C  CA    . ALA   F 3 537 ? 38.376  92.609  -56.902 1.00 49.40  ? 830  ALA   D CA    1 
ATOM   9684  C  C     . ALA   F 3 537 ? 37.560  91.316  -56.756 1.00 51.35  ? 830  ALA   D C     1 
ATOM   9685  O  O     . ALA   F 3 537 ? 37.530  90.748  -55.673 1.00 58.61  ? 830  ALA   D O     1 
ATOM   9686  C  CB    . ALA   F 3 537 ? 37.933  93.634  -55.886 1.00 48.80  ? 830  ALA   D CB    1 
ATOM   9687  N  N     . LYS   F 3 538 ? 36.877  90.851  -57.809 1.00 51.79  ? 831  LYS   D N     1 
ATOM   9688  C  CA    . LYS   F 3 538 ? 36.104  89.617  -57.744 1.00 52.46  ? 831  LYS   D CA    1 
ATOM   9689  C  C     . LYS   F 3 538 ? 36.492  88.673  -58.882 1.00 53.01  ? 831  LYS   D C     1 
ATOM   9690  O  O     . LYS   F 3 538 ? 35.789  87.701  -59.129 1.00 59.84  ? 831  LYS   D O     1 
ATOM   9691  C  CB    . LYS   F 3 538 ? 34.607  89.942  -57.815 1.00 56.12  ? 831  LYS   D CB    1 
ATOM   9692  C  CG    . LYS   F 3 538 ? 34.069  90.833  -56.693 1.00 60.45  ? 831  LYS   D CG    1 
ATOM   9693  C  CD    . LYS   F 3 538 ? 33.125  90.147  -55.722 1.00 59.00  ? 831  LYS   D CD    1 
ATOM   9694  C  CE    . LYS   F 3 538 ? 31.680  90.179  -56.181 1.00 62.38  ? 831  LYS   D CE    1 
ATOM   9695  N  NZ    . LYS   F 3 538 ? 30.779  89.417  -55.282 1.00 54.97  ? 831  LYS   D NZ    1 
ATOM   9696  N  N     . GLU   F 3 539 ? 37.603  88.958  -59.574 1.00 59.82  ? 832  GLU   D N     1 
ATOM   9697  C  CA    . GLU   F 3 539 ? 38.048  88.145  -60.699 1.00 67.17  ? 832  GLU   D CA    1 
ATOM   9698  C  C     . GLU   F 3 539 ? 38.763  86.896  -60.173 1.00 66.36  ? 832  GLU   D C     1 
ATOM   9699  O  O     . GLU   F 3 539 ? 38.403  85.814  -60.654 1.00 76.55  ? 832  GLU   D O     1 
ATOM   9700  C  CB    . GLU   F 3 539 ? 38.971  88.941  -61.629 1.00 69.11  ? 832  GLU   D CB    1 
ATOM   9701  C  CG    . GLU   F 3 539 ? 38.219  89.738  -62.682 1.00 73.09  ? 832  GLU   D CG    1 
ATOM   9702  C  CD    . GLU   F 3 539 ? 39.056  90.753  -63.447 1.00 80.65  ? 832  GLU   D CD    1 
ATOM   9703  O  OE1   . GLU   F 3 539 ? 40.298  90.769  -63.249 1.00 75.95  ? 832  GLU   D OE1   1 
ATOM   9704  O  OE2   . GLU   F 3 539 ? 38.460  91.548  -64.225 1.00 77.33  ? 832  GLU   D OE2   1 
HETATM 9705  MG MG    . MG    G 4 .   ? 43.271  59.020  -5.461  1.00 60.29  ? 201  MG    B MG    1 
HETATM 9706  MG MG    . MG    H 4 .   ? 31.250  80.647  -10.017 1.00 32.41  ? 901  MG    A MG    1 
HETATM 9707  MG MG    . MG    I 4 .   ? 33.975  79.742  -9.202  1.00 46.66  ? 902  MG    A MG    1 
HETATM 9708  O  O36   . A1LWE J 5 .   ? 30.753  69.900  -5.619  1.00 31.86  ? 903  A1LWE A O36   1 
HETATM 9709  C  C36   . A1LWE J 5 .   ? 30.613  70.102  -6.831  1.00 28.43  ? 903  A1LWE A C36   1 
HETATM 9710  N  N31   . A1LWE J 5 .   ? 30.006  69.126  -7.621  1.00 29.18  ? 903  A1LWE A N31   1 
HETATM 9711  C  C32   . A1LWE J 5 .   ? 29.771  69.220  -8.964  1.00 29.23  ? 903  A1LWE A C32   1 
HETATM 9712  N  N32   . A1LWE J 5 .   ? 29.156  68.173  -9.533  1.00 30.81  ? 903  A1LWE A N32   1 
HETATM 9713  N  N33   . A1LWE J 5 .   ? 30.126  70.275  -9.695  1.00 30.10  ? 903  A1LWE A N33   1 
HETATM 9714  C  C35   . A1LWE J 5 .   ? 30.976  71.230  -7.591  1.00 25.63  ? 903  A1LWE A C35   1 
HETATM 9715  C  C34   . A1LWE J 5 .   ? 30.718  71.235  -8.944  1.00 28.18  ? 903  A1LWE A C34   1 
HETATM 9716  N  N37   . A1LWE J 5 .   ? 31.571  72.426  -7.208  1.00 27.28  ? 903  A1LWE A N37   1 
HETATM 9717  C  C38   . A1LWE J 5 .   ? 31.647  73.128  -8.325  1.00 26.20  ? 903  A1LWE A C38   1 
HETATM 9718  N  N39   . A1LWE J 5 .   ? 31.177  72.439  -9.416  1.00 27.49  ? 903  A1LWE A N39   1 
HETATM 9719  C  C41   . A1LWE J 5 .   ? 30.982  72.949  -10.777 1.00 32.83  ? 903  A1LWE A C41   1 
HETATM 9720  O  O44   . A1LWE J 5 .   ? 31.790  74.097  -10.907 1.00 32.48  ? 903  A1LWE A O44   1 
HETATM 9721  C  C42   . A1LWE J 5 .   ? 29.522  73.404  -10.994 1.00 35.96  ? 903  A1LWE A C42   1 
HETATM 9722  C  C46   . A1LWE J 5 .   ? 28.885  71.857  -12.669 1.00 48.24  ? 903  A1LWE A C46   1 
HETATM 9723  O  O42   . A1LWE J 5 .   ? 28.998  73.233  -12.297 1.00 41.02  ? 903  A1LWE A O42   1 
HETATM 9724  C  C43   . A1LWE J 5 .   ? 29.585  74.914  -10.726 1.00 38.61  ? 903  A1LWE A C43   1 
HETATM 9725  O  O43   . A1LWE J 5 .   ? 28.570  75.762  -11.281 1.00 44.01  ? 903  A1LWE A O43   1 
HETATM 9726  C  C44   . A1LWE J 5 .   ? 30.974  75.231  -11.288 1.00 32.11  ? 903  A1LWE A C44   1 
HETATM 9727  C  C45   . A1LWE J 5 .   ? 31.624  76.485  -10.764 1.00 35.29  ? 903  A1LWE A C45   1 
HETATM 9728  O  O45   . A1LWE J 5 .   ? 31.898  76.319  -9.352  1.00 35.56  ? 903  A1LWE A O45   1 
HETATM 9729  P  PA    . A1LWE J 5 .   ? 31.709  77.560  -8.375  1.00 33.36  ? 903  A1LWE A PA    1 
HETATM 9730  O  O1A   . A1LWE J 5 .   ? 32.199  77.135  -7.027  1.00 39.77  ? 903  A1LWE A O1A   1 
HETATM 9731  O  O2A   . A1LWE J 5 .   ? 32.029  78.922  -9.050  1.00 28.89  ? 903  A1LWE A O2A   1 
HETATM 9732  O  O1B   . A1LWE J 5 .   ? 30.096  77.420  -8.243  1.00 36.64  ? 903  A1LWE A O1B   1 
HETATM 9733  P  PB    . A1LWE J 5 .   ? 29.020  78.471  -8.842  1.00 30.66  ? 903  A1LWE A PB    1 
HETATM 9734  O  O2B   . A1LWE J 5 .   ? 27.801  77.676  -9.155  1.00 32.09  ? 903  A1LWE A O2B   1 
HETATM 9735  O  O3B   . A1LWE J 5 .   ? 29.714  79.316  -9.861  1.00 25.14  ? 903  A1LWE A O3B   1 
HETATM 9736  O  O3A   . A1LWE J 5 .   ? 28.782  79.439  -7.601  1.00 32.12  ? 903  A1LWE A O3A   1 
HETATM 9737  P  PG    . A1LWE J 5 .   ? 29.366  80.907  -7.287  1.00 34.98  ? 903  A1LWE A PG    1 
HETATM 9738  O  O1G   . A1LWE J 5 .   ? 29.608  80.825  -5.828  1.00 35.54  ? 903  A1LWE A O1G   1 
HETATM 9739  O  O2G   . A1LWE J 5 .   ? 30.474  81.276  -8.245  1.00 38.92  ? 903  A1LWE A O2G   1 
HETATM 9740  O  O25   . A1LWE J 5 .   ? 28.095  81.821  -7.608  1.00 29.86  ? 903  A1LWE A O25   1 
HETATM 9741  C  C1    . PEG   K 6 .   ? 23.913  74.787  -33.524 1.00 65.09  ? 904  PEG   A C1    1 
HETATM 9742  C  C2    . PEG   K 6 .   ? 22.542  75.052  -32.926 1.00 73.82  ? 904  PEG   A C2    1 
HETATM 9743  O  O2    . PEG   K 6 .   ? 22.607  76.007  -31.861 1.00 72.10  ? 904  PEG   A O2    1 
HETATM 9744  C  C3    . PEG   K 6 .   ? 22.641  75.414  -30.557 1.00 73.91  ? 904  PEG   A C3    1 
HETATM 9745  C  C4    . PEG   K 6 .   ? 22.803  76.476  -29.488 1.00 77.39  ? 904  PEG   A C4    1 
HETATM 9746  O  O4    . PEG   K 6 .   ? 21.759  76.479  -28.512 1.00 69.04  ? 904  PEG   A O4    1 
HETATM 9747  P  P     . PO4   L 7 .   ? 44.190  74.967  -40.659 1.00 97.51  ? 905  PO4   A P     1 
HETATM 9748  O  O1    . PO4   L 7 .   ? 42.868  74.947  -41.428 1.00 95.83  ? 905  PO4   A O1    1 
HETATM 9749  O  O2    . PO4   L 7 .   ? 44.805  76.357  -40.754 1.00 89.71  ? 905  PO4   A O2    1 
HETATM 9750  O  O3    . PO4   L 7 .   ? 45.143  73.924  -41.255 1.00 106.57 ? 905  PO4   A O3    1 
HETATM 9751  O  O4    . PO4   L 7 .   ? 43.939  74.628  -39.194 1.00 109.39 ? 905  PO4   A O4    1 
HETATM 9752  MG MG    . MG    M 4 .   ? 6.349   96.082  -56.945 1.00 63.79  ? 201  MG    E MG    1 
HETATM 9753  MG MG    . MG    N 4 .   ? 27.616  84.268  -52.160 1.00 34.78  ? 901  MG    D MG    1 
HETATM 9754  MG MG    . MG    O 4 .   ? 27.082  87.185  -53.080 1.00 53.29  ? 902  MG    D MG    1 
HETATM 9755  O  O36   . A1LWE P 5 .   ? 16.862  83.707  -56.540 1.00 31.26  ? 903  A1LWE D O36   1 
HETATM 9756  C  C36   . A1LWE P 5 .   ? 17.072  83.566  -55.331 1.00 28.51  ? 903  A1LWE D C36   1 
HETATM 9757  N  N31   . A1LWE P 5 .   ? 16.109  82.942  -54.537 1.00 28.89  ? 903  A1LWE D N31   1 
HETATM 9758  C  C32   . A1LWE P 5 .   ? 16.207  82.732  -53.190 1.00 28.86  ? 903  A1LWE D C32   1 
HETATM 9759  N  N32   . A1LWE P 5 .   ? 15.163  82.128  -52.606 1.00 31.99  ? 903  A1LWE D N32   1 
HETATM 9760  N  N33   . A1LWE P 5 .   ? 17.264  83.103  -52.468 1.00 30.50  ? 903  A1LWE D N33   1 
HETATM 9761  C  C35   . A1LWE P 5 .   ? 18.212  83.928  -54.578 1.00 25.47  ? 903  A1LWE D C35   1 
HETATM 9762  C  C34   . A1LWE P 5 .   ? 18.225  83.685  -53.222 1.00 28.02  ? 903  A1LWE D C34   1 
HETATM 9763  N  N37   . A1LWE P 5 .   ? 19.397  84.527  -54.967 1.00 24.95  ? 903  A1LWE D N37   1 
HETATM 9764  C  C38   . A1LWE P 5 .   ? 20.113  84.607  -53.858 1.00 26.10  ? 903  A1LWE D C38   1 
HETATM 9765  N  N39   . A1LWE P 5 .   ? 19.431  84.147  -52.754 1.00 27.39  ? 903  A1LWE D N39   1 
HETATM 9766  C  C41   . A1LWE P 5 .   ? 19.950  83.950  -51.399 1.00 32.95  ? 903  A1LWE D C41   1 
HETATM 9767  O  O44   . A1LWE P 5 .   ? 21.094  84.761  -51.258 1.00 32.55  ? 903  A1LWE D O44   1 
HETATM 9768  C  C42   . A1LWE P 5 .   ? 20.428  82.497  -51.189 1.00 36.29  ? 903  A1LWE D C42   1 
HETATM 9769  C  C46   . A1LWE P 5 .   ? 18.936  81.854  -49.459 1.00 46.50  ? 903  A1LWE D C46   1 
HETATM 9770  O  O42   . A1LWE P 5 .   ? 20.300  81.992  -49.874 1.00 41.14  ? 903  A1LWE D O42   1 
HETATM 9771  C  C43   . A1LWE P 5 .   ? 21.932  82.579  -51.487 1.00 38.76  ? 903  A1LWE D C43   1 
HETATM 9772  O  O43   . A1LWE P 5 .   ? 22.824  81.567  -50.998 1.00 42.42  ? 903  A1LWE D O43   1 
HETATM 9773  C  C44   . A1LWE P 5 .   ? 22.236  83.951  -50.885 1.00 33.25  ? 903  A1LWE D C44   1 
HETATM 9774  C  C45   . A1LWE P 5 .   ? 23.477  84.619  -51.412 1.00 36.45  ? 903  A1LWE D C45   1 
HETATM 9775  O  O45   . A1LWE P 5 .   ? 23.272  84.869  -52.821 1.00 36.26  ? 903  A1LWE D O45   1 
HETATM 9776  P  PA    . A1LWE P 5 .   ? 24.480  84.677  -53.834 1.00 34.59  ? 903  A1LWE D PA    1 
HETATM 9777  O  O1A   . A1LWE P 5 .   ? 24.137  85.253  -55.167 1.00 40.07  ? 903  A1LWE D O1A   1 
HETATM 9778  O  O2A   . A1LWE P 5 .   ? 25.780  85.017  -53.168 1.00 26.00  ? 903  A1LWE D O2A   1 
HETATM 9779  O  O1B   . A1LWE P 5 .   ? 24.404  83.065  -53.968 1.00 37.25  ? 903  A1LWE D O1B   1 
HETATM 9780  P  PB    . A1LWE P 5 .   ? 25.473  81.999  -53.372 1.00 31.22  ? 903  A1LWE D PB    1 
HETATM 9781  O  O2B   . A1LWE P 5 .   ? 24.731  80.747  -53.126 1.00 33.09  ? 903  A1LWE D O2B   1 
HETATM 9782  O  O3B   . A1LWE P 5 .   ? 26.300  82.623  -52.324 1.00 25.34  ? 903  A1LWE D O3B   1 
HETATM 9783  O  O3A   . A1LWE P 5 .   ? 26.446  81.830  -54.619 1.00 32.32  ? 903  A1LWE D O3A   1 
HETATM 9784  P  PG    . A1LWE P 5 .   ? 27.955  82.295  -54.896 1.00 34.93  ? 903  A1LWE D PG    1 
HETATM 9785  O  O1G   . A1LWE P 5 .   ? 27.945  82.764  -56.304 1.00 35.38  ? 903  A1LWE D O1G   1 
HETATM 9786  O  O2G   . A1LWE P 5 .   ? 28.845  81.159  -54.468 1.00 32.96  ? 903  A1LWE D O2G   1 
HETATM 9787  O  O25   . A1LWE P 5 .   ? 28.219  83.538  -53.925 1.00 39.80  ? 903  A1LWE D O25   1 
HETATM 9788  C  C1    . PEG   Q 6 .   ? 15.767  75.150  -36.801 1.00 89.51  ? 904  PEG   D C1    1 
HETATM 9789  O  O1    . PEG   Q 6 .   ? 15.172  75.854  -37.889 1.00 80.73  ? 904  PEG   D O1    1 
HETATM 9790  C  C2    . PEG   Q 6 .   ? 16.971  74.327  -37.204 1.00 91.47  ? 904  PEG   D C2    1 
HETATM 9791  O  O2    . PEG   Q 6 .   ? 17.862  74.159  -36.100 1.00 101.68 ? 904  PEG   D O2    1 
HETATM 9792  C  C3    . PEG   Q 6 .   ? 18.814  73.113  -36.285 1.00 99.35  ? 904  PEG   D C3    1 
HETATM 9793  C  C4    . PEG   Q 6 .   ? 19.641  72.929  -35.043 1.00 100.49 ? 904  PEG   D C4    1 
HETATM 9794  O  O4    . PEG   Q 6 .   ? 20.950  73.454  -35.185 1.00 95.67  ? 904  PEG   D O4    1 
HETATM 9795  P  P     . PO4   R 7 .   ? 22.150  97.191  -21.509 1.00 96.50  ? 905  PO4   D P     1 
HETATM 9796  O  O1    . PO4   R 7 .   ? 21.089  97.574  -22.543 1.00 96.52  ? 905  PO4   D O1    1 
HETATM 9797  O  O2    . PO4   R 7 .   ? 23.363  96.589  -22.215 1.00 87.89  ? 905  PO4   D O2    1 
HETATM 9798  O  O3    . PO4   R 7 .   ? 21.563  96.172  -20.528 1.00 86.71  ? 905  PO4   D O3    1 
HETATM 9799  O  O4    . PO4   R 7 .   ? 22.589  98.442  -20.751 1.00 100.73 ? 905  PO4   D O4    1 
HETATM 9800  O  O     . HOH   S 8 .   ? 60.561  55.953  -4.646  1.00 57.56  ? 301  HOH   B O     1 
HETATM 9801  O  O     . HOH   S 8 .   ? 39.289  67.611  7.293   1.00 45.82  ? 302  HOH   B O     1 
HETATM 9802  O  O     . HOH   S 8 .   ? 48.431  51.371  -0.685  1.00 56.17  ? 303  HOH   B O     1 
HETATM 9803  O  O     . HOH   S 8 .   ? 40.398  73.118  -9.104  1.00 25.76  ? 304  HOH   B O     1 
HETATM 9804  O  O     . HOH   S 8 .   ? 45.999  55.631  2.412   1.00 45.72  ? 305  HOH   B O     1 
HETATM 9805  O  O     . HOH   S 8 .   ? 52.012  50.899  -3.463  1.00 50.14  ? 306  HOH   B O     1 
HETATM 9806  O  O     . HOH   S 8 .   ? 37.674  65.895  -2.847  1.00 40.84  ? 307  HOH   B O     1 
HETATM 9807  O  O     . HOH   S 8 .   ? 37.730  68.106  -1.032  1.00 42.89  ? 308  HOH   B O     1 
HETATM 9808  O  O     . HOH   S 8 .   ? 42.204  69.164  6.007   1.00 40.28  ? 309  HOH   B O     1 
HETATM 9809  O  O     . HOH   S 8 .   ? 43.071  57.772  -3.758  1.00 35.92  ? 310  HOH   B O     1 
HETATM 9810  O  O     . HOH   S 8 .   ? 35.303  80.838  -3.896  1.00 41.35  ? 311  HOH   B O     1 
HETATM 9811  O  O     . HOH   S 8 .   ? 45.407  59.552  -4.835  1.00 41.78  ? 312  HOH   B O     1 
HETATM 9812  O  O     . HOH   S 8 .   ? 35.176  76.530  -1.379  1.00 33.65  ? 313  HOH   B O     1 
HETATM 9813  O  O     . HOH   S 8 .   ? 40.051  77.026  2.946   1.00 32.70  ? 314  HOH   B O     1 
HETATM 9814  O  O     . HOH   S 8 .   ? 58.177  57.896  -2.451  1.00 57.98  ? 315  HOH   B O     1 
HETATM 9815  O  O     . HOH   S 8 .   ? 40.786  59.386  -2.731  1.00 40.17  ? 316  HOH   B O     1 
HETATM 9816  O  O     . HOH   S 8 .   ? 45.132  59.508  4.761   1.00 42.58  ? 317  HOH   B O     1 
HETATM 9817  O  O     . HOH   S 8 .   ? 47.889  59.673  -5.965  1.00 43.35  ? 318  HOH   B O     1 
HETATM 9818  O  O     . HOH   S 8 .   ? 34.055  70.663  -2.619  1.00 36.04  ? 319  HOH   B O     1 
HETATM 9819  O  O     . HOH   S 8 .   ? 52.671  57.993  -4.833  1.00 52.99  ? 320  HOH   B O     1 
HETATM 9820  O  O     . HOH   S 8 .   ? 35.868  74.344  -1.687  1.00 46.15  ? 321  HOH   B O     1 
HETATM 9821  O  O     . HOH   S 8 .   ? 54.045  48.967  -4.872  1.00 65.68  ? 322  HOH   B O     1 
HETATM 9822  O  O     . HOH   T 8 .   ? 38.513  63.271  -11.359 1.00 34.96  ? 301  HOH   C O     1 
HETATM 9823  O  O     . HOH   T 8 .   ? 31.366  57.896  -11.621 1.00 39.33  ? 302  HOH   C O     1 
HETATM 9824  O  O     . HOH   T 8 .   ? 35.223  62.140  -10.259 1.00 43.62  ? 303  HOH   C O     1 
HETATM 9825  O  O     . HOH   T 8 .   ? 57.310  46.513  -3.667  1.00 73.50  ? 304  HOH   C O     1 
HETATM 9826  O  O     . HOH   T 8 .   ? 43.621  63.330  -12.072 1.00 42.68  ? 305  HOH   C O     1 
HETATM 9827  O  O     . HOH   T 8 .   ? 53.691  62.944  -1.429  1.00 49.68  ? 306  HOH   C O     1 
HETATM 9828  O  O     . HOH   T 8 .   ? 52.535  60.660  -3.407  1.00 51.95  ? 307  HOH   C O     1 
HETATM 9829  O  O     . HOH   T 8 .   ? 32.794  64.215  -5.684  1.00 45.21  ? 308  HOH   C O     1 
HETATM 9830  O  O     . HOH   T 8 .   ? 41.312  62.538  -17.636 1.00 35.34  ? 309  HOH   C O     1 
HETATM 9831  O  O     . HOH   T 8 .   ? 42.278  71.104  -9.439  1.00 26.77  ? 310  HOH   C O     1 
HETATM 9832  O  O     . HOH   T 8 .   ? 33.535  58.808  -11.411 1.00 42.40  ? 311  HOH   C O     1 
HETATM 9833  O  O     . HOH   T 8 .   ? 35.212  63.453  -7.881  1.00 46.89  ? 312  HOH   C O     1 
HETATM 9834  O  O     . HOH   T 8 .   ? 50.611  65.295  -7.854  1.00 49.42  ? 313  HOH   C O     1 
HETATM 9835  O  O     . HOH   T 8 .   ? 53.224  56.734  11.577  1.00 39.79  ? 314  HOH   C O     1 
HETATM 9836  O  O     . HOH   T 8 .   ? 42.450  63.361  -9.880  1.00 43.50  ? 315  HOH   C O     1 
HETATM 9837  O  O     . HOH   T 8 .   ? 49.410  61.830  -5.770  1.00 45.78  ? 316  HOH   C O     1 
HETATM 9838  O  O     . HOH   T 8 .   ? 41.017  62.097  -7.075  1.00 43.11  ? 317  HOH   C O     1 
HETATM 9839  O  O     . HOH   T 8 .   ? 53.217  70.404  -7.331  1.00 28.62  ? 318  HOH   C O     1 
HETATM 9840  O  O     . HOH   T 8 .   ? 33.707  61.631  -8.275  1.00 46.93  ? 319  HOH   C O     1 
HETATM 9841  O  O     . HOH   T 8 .   ? 46.295  69.274  -2.721  1.00 37.72  ? 320  HOH   C O     1 
HETATM 9842  O  O     . HOH   T 8 .   ? 45.653  69.938  -6.000  1.00 34.26  ? 321  HOH   C O     1 
HETATM 9843  O  O     . HOH   T 8 .   ? 49.528  52.811  3.287   1.00 48.97  ? 322  HOH   C O     1 
HETATM 9844  O  O     . HOH   T 8 .   ? 37.821  62.954  -6.601  1.00 33.75  ? 323  HOH   C O     1 
HETATM 9845  O  O     . HOH   T 8 .   ? 48.687  60.262  4.870   1.00 39.26  ? 324  HOH   C O     1 
HETATM 9846  O  O     . HOH   T 8 .   ? 38.596  70.139  -12.519 1.00 27.19  ? 325  HOH   C O     1 
HETATM 9847  O  O     . HOH   T 8 .   ? 57.682  56.865  2.860   1.00 50.18  ? 326  HOH   C O     1 
HETATM 9848  O  O     . HOH   T 8 .   ? 56.784  56.788  5.128   1.00 40.30  ? 327  HOH   C O     1 
HETATM 9849  O  O     . HOH   T 8 .   ? 34.634  65.962  -4.799  1.00 43.04  ? 328  HOH   C O     1 
HETATM 9850  O  O     . HOH   T 8 .   ? 52.233  71.893  -4.080  1.00 57.15  ? 329  HOH   C O     1 
HETATM 9851  O  O     . HOH   T 8 .   ? 31.600  66.305  -1.644  1.00 37.75  ? 330  HOH   C O     1 
HETATM 9852  O  O     . HOH   T 8 .   ? 45.441  61.852  -8.033  1.00 42.47  ? 331  HOH   C O     1 
HETATM 9853  O  O     . HOH   T 8 .   ? 43.436  60.597  -7.062  1.00 50.52  ? 332  HOH   C O     1 
HETATM 9854  O  O     . HOH   T 8 .   ? 40.317  61.971  -10.034 1.00 46.70  ? 333  HOH   C O     1 
HETATM 9855  O  O     . HOH   U 8 .   ? 33.083  75.560  -14.024 1.00 28.87  ? 1001 HOH   A O     1 
HETATM 9856  O  O     . HOH   U 8 .   ? 30.806  62.171  -35.771 1.00 50.53  ? 1002 HOH   A O     1 
HETATM 9857  O  O     . HOH   U 8 .   ? 33.303  75.752  -4.724  1.00 29.35  ? 1003 HOH   A O     1 
HETATM 9858  O  O     . HOH   U 8 .   ? 54.724  64.474  16.523  1.00 42.64  ? 1004 HOH   A O     1 
HETATM 9859  O  O     . HOH   U 8 .   ? 50.404  82.911  -14.425 1.00 34.47  ? 1005 HOH   A O     1 
HETATM 9860  O  O     . HOH   U 8 .   ? 57.540  68.649  -30.683 1.00 40.00  ? 1006 HOH   A O     1 
HETATM 9861  O  O     . HOH   U 8 .   ? 24.404  61.278  -33.784 1.00 51.64  ? 1007 HOH   A O     1 
HETATM 9862  O  O     . HOH   U 8 .   ? 62.530  79.838  -5.341  1.00 44.64  ? 1008 HOH   A O     1 
HETATM 9863  O  O     . HOH   U 8 .   ? 59.078  87.078  -22.576 1.00 45.49  ? 1009 HOH   A O     1 
HETATM 9864  O  O     . HOH   U 8 .   ? 14.565  69.567  -21.381 1.00 27.51  ? 1010 HOH   A O     1 
HETATM 9865  O  O     . HOH   U 8 .   ? 45.691  83.477  -28.962 1.00 37.67  ? 1011 HOH   A O     1 
HETATM 9866  O  O     . HOH   U 8 .   ? 53.385  67.395  -9.963  1.00 38.90  ? 1012 HOH   A O     1 
HETATM 9867  O  O     . HOH   U 8 .   ? 48.295  79.773  -31.450 1.00 53.60  ? 1013 HOH   A O     1 
HETATM 9868  O  O     . HOH   U 8 .   ? 65.461  87.389  -9.283  1.00 46.17  ? 1014 HOH   A O     1 
HETATM 9869  O  O     . HOH   U 8 .   ? 10.286  73.664  -15.377 1.00 51.08  ? 1015 HOH   A O     1 
HETATM 9870  O  O     . HOH   U 8 .   ? 36.633  72.674  -41.997 1.00 48.74  ? 1016 HOH   A O     1 
HETATM 9871  O  O     . HOH   U 8 .   ? 40.278  84.749  7.784   1.00 49.27  ? 1017 HOH   A O     1 
HETATM 9872  O  O     . HOH   U 8 .   ? 14.134  69.385  -3.322  1.00 41.49  ? 1018 HOH   A O     1 
HETATM 9873  O  O     . HOH   U 8 .   ? 51.243  71.909  -19.091 1.00 42.94  ? 1019 HOH   A O     1 
HETATM 9874  O  O     . HOH   U 8 .   ? 40.189  57.447  -31.502 1.00 34.85  ? 1020 HOH   A O     1 
HETATM 9875  O  O     . HOH   U 8 .   ? 28.548  91.746  -22.872 1.00 44.21  ? 1021 HOH   A O     1 
HETATM 9876  O  O     . HOH   U 8 .   ? 37.154  87.634  -0.823  1.00 47.60  ? 1022 HOH   A O     1 
HETATM 9877  O  O     . HOH   U 8 .   ? 10.424  65.411  -16.539 1.00 49.65  ? 1023 HOH   A O     1 
HETATM 9878  O  O     . HOH   U 8 .   ? 40.527  62.100  -20.040 1.00 34.75  ? 1024 HOH   A O     1 
HETATM 9879  O  O     . HOH   U 8 .   ? 26.362  85.697  -23.817 1.00 37.04  ? 1025 HOH   A O     1 
HETATM 9880  O  O     . HOH   U 8 .   ? 25.401  61.827  -27.585 1.00 43.99  ? 1026 HOH   A O     1 
HETATM 9881  O  O     . HOH   U 8 .   ? 49.630  74.908  -29.545 1.00 28.56  ? 1027 HOH   A O     1 
HETATM 9882  O  O     . HOH   U 8 .   ? 31.745  88.497  -25.721 1.00 44.02  ? 1028 HOH   A O     1 
HETATM 9883  O  O     . HOH   U 8 .   ? 44.897  59.348  -40.707 1.00 42.07  ? 1029 HOH   A O     1 
HETATM 9884  O  O     . HOH   U 8 .   ? 15.121  82.376  -22.203 1.00 52.86  ? 1030 HOH   A O     1 
HETATM 9885  O  O     . HOH   U 8 .   ? 30.765  52.776  -14.078 1.00 43.25  ? 1031 HOH   A O     1 
HETATM 9886  O  O     . HOH   U 8 .   ? 54.045  84.724  12.845  1.00 47.53  ? 1032 HOH   A O     1 
HETATM 9887  O  O     . HOH   U 8 .   ? 66.834  70.602  -14.835 1.00 49.87  ? 1033 HOH   A O     1 
HETATM 9888  O  O     . HOH   U 8 .   ? 31.689  54.586  -26.075 1.00 39.04  ? 1034 HOH   A O     1 
HETATM 9889  O  O     . HOH   U 8 .   ? 38.161  90.331  -28.839 1.00 34.77  ? 1035 HOH   A O     1 
HETATM 9890  O  O     . HOH   U 8 .   ? 13.535  63.289  -22.355 1.00 34.84  ? 1036 HOH   A O     1 
HETATM 9891  O  O     . HOH   U 8 .   ? 41.480  71.606  -22.063 1.00 29.51  ? 1037 HOH   A O     1 
HETATM 9892  O  O     . HOH   U 8 .   ? 36.140  66.111  -27.717 1.00 25.01  ? 1038 HOH   A O     1 
HETATM 9893  O  O     . HOH   U 8 .   ? 50.550  89.216  -9.467  1.00 31.62  ? 1039 HOH   A O     1 
HETATM 9894  O  O     . HOH   U 8 .   ? 31.949  73.872  3.563   1.00 43.15  ? 1040 HOH   A O     1 
HETATM 9895  O  O     . HOH   U 8 .   ? 36.539  59.970  -24.112 1.00 33.03  ? 1041 HOH   A O     1 
HETATM 9896  O  O     . HOH   U 8 .   ? 49.903  80.565  16.612  1.00 42.29  ? 1042 HOH   A O     1 
HETATM 9897  O  O     . HOH   U 8 .   ? 31.198  91.886  -4.264  1.00 58.11  ? 1043 HOH   A O     1 
HETATM 9898  O  O     . HOH   U 8 .   ? 43.064  90.756  -32.362 1.00 53.29  ? 1044 HOH   A O     1 
HETATM 9899  O  O     . HOH   U 8 .   ? 43.355  79.747  -35.513 1.00 53.14  ? 1045 HOH   A O     1 
HETATM 9900  O  O     . HOH   U 8 .   ? 37.924  56.465  -25.296 1.00 40.20  ? 1046 HOH   A O     1 
HETATM 9901  O  O     . HOH   U 8 .   ? 17.613  76.502  -24.371 1.00 34.16  ? 1047 HOH   A O     1 
HETATM 9902  O  O     . HOH   U 8 .   ? 26.035  69.518  -29.512 1.00 37.74  ? 1048 HOH   A O     1 
HETATM 9903  O  O     . HOH   U 8 .   ? 27.406  64.059  -32.517 1.00 48.46  ? 1049 HOH   A O     1 
HETATM 9904  O  O     . HOH   U 8 .   ? 47.384  55.257  7.844   1.00 50.98  ? 1050 HOH   A O     1 
HETATM 9905  O  O     . HOH   U 8 .   ? 20.402  63.130  -10.894 1.00 40.96  ? 1051 HOH   A O     1 
HETATM 9906  O  O     . HOH   U 8 .   ? 19.794  69.902  -6.498  1.00 45.11  ? 1052 HOH   A O     1 
HETATM 9907  O  O     . HOH   U 8 .   ? 70.040  82.258  -34.092 1.00 60.03  ? 1053 HOH   A O     1 
HETATM 9908  O  O     . HOH   U 8 .   ? 20.860  86.773  -14.611 1.00 47.71  ? 1054 HOH   A O     1 
HETATM 9909  O  O     . HOH   U 8 .   ? 18.095  56.125  -18.346 1.00 54.47  ? 1055 HOH   A O     1 
HETATM 9910  O  O     . HOH   U 8 .   ? 32.345  67.237  -34.970 1.00 33.03  ? 1056 HOH   A O     1 
HETATM 9911  O  O     . HOH   U 8 .   ? 12.447  86.985  -6.381  1.00 60.82  ? 1057 HOH   A O     1 
HETATM 9912  O  O     . HOH   U 8 .   ? 34.604  58.606  -20.176 1.00 40.96  ? 1058 HOH   A O     1 
HETATM 9913  O  O     . HOH   U 8 .   ? 20.123  62.759  -6.581  1.00 39.57  ? 1059 HOH   A O     1 
HETATM 9914  O  O     . HOH   U 8 .   ? 32.570  81.706  -6.624  1.00 46.70  ? 1060 HOH   A O     1 
HETATM 9915  O  O     . HOH   U 8 .   ? 26.363  69.126  5.028   1.00 46.84  ? 1061 HOH   A O     1 
HETATM 9916  O  O     . HOH   U 8 .   ? 27.008  69.656  2.244   1.00 36.97  ? 1062 HOH   A O     1 
HETATM 9917  O  O     . HOH   U 8 .   ? 25.476  91.280  -15.481 1.00 60.55  ? 1063 HOH   A O     1 
HETATM 9918  O  O     . HOH   U 8 .   ? 29.516  61.929  11.628  1.00 71.54  ? 1064 HOH   A O     1 
HETATM 9919  O  O     . HOH   U 8 .   ? 30.727  70.290  1.102   1.00 51.14  ? 1065 HOH   A O     1 
HETATM 9920  O  O     . HOH   U 8 .   ? 30.518  69.141  -12.505 1.00 28.76  ? 1066 HOH   A O     1 
HETATM 9921  O  O     . HOH   U 8 .   ? 46.104  58.189  -25.974 1.00 34.15  ? 1067 HOH   A O     1 
HETATM 9922  O  O     . HOH   U 8 .   ? 49.178  67.884  -24.375 1.00 32.01  ? 1068 HOH   A O     1 
HETATM 9923  O  O     . HOH   U 8 .   ? 50.294  73.208  -27.482 1.00 31.56  ? 1069 HOH   A O     1 
HETATM 9924  O  O     . HOH   U 8 .   ? 59.832  60.624  -30.713 1.00 41.98  ? 1070 HOH   A O     1 
HETATM 9925  O  O     . HOH   U 8 .   ? 69.791  70.218  -30.431 1.00 46.17  ? 1071 HOH   A O     1 
HETATM 9926  O  O     . HOH   U 8 .   ? 42.616  53.527  -35.540 1.00 50.12  ? 1072 HOH   A O     1 
HETATM 9927  O  O     . HOH   U 8 .   ? 51.318  63.488  15.437  1.00 43.48  ? 1073 HOH   A O     1 
HETATM 9928  O  O     . HOH   U 8 .   ? 57.538  79.097  -10.110 1.00 41.92  ? 1074 HOH   A O     1 
HETATM 9929  O  O     . HOH   U 8 .   ? 45.310  64.231  -16.484 1.00 44.42  ? 1075 HOH   A O     1 
HETATM 9930  O  O     . HOH   U 8 .   ? 56.782  69.223  -20.411 1.00 44.67  ? 1076 HOH   A O     1 
HETATM 9931  O  O     . HOH   U 8 .   ? 41.370  102.092 -12.916 1.00 58.86  ? 1077 HOH   A O     1 
HETATM 9932  O  O     . HOH   U 8 .   ? 43.424  84.909  -28.788 1.00 38.14  ? 1078 HOH   A O     1 
HETATM 9933  O  O     . HOH   U 8 .   ? 23.254  50.609  -27.530 1.00 55.71  ? 1079 HOH   A O     1 
HETATM 9934  O  O     . HOH   U 8 .   ? 57.969  87.043  7.873   1.00 45.27  ? 1080 HOH   A O     1 
HETATM 9935  O  O     . HOH   U 8 .   ? 22.990  57.603  -9.995  1.00 41.48  ? 1081 HOH   A O     1 
HETATM 9936  O  O     . HOH   U 8 .   ? 27.178  73.838  -32.866 1.00 51.32  ? 1082 HOH   A O     1 
HETATM 9937  O  O     . HOH   U 8 .   ? 56.089  75.408  -12.811 1.00 43.21  ? 1083 HOH   A O     1 
HETATM 9938  O  O     . HOH   U 8 .   ? 26.871  75.718  -30.651 1.00 45.06  ? 1084 HOH   A O     1 
HETATM 9939  O  O     . HOH   U 8 .   ? 43.107  71.503  -11.897 1.00 31.55  ? 1085 HOH   A O     1 
HETATM 9940  O  O     . HOH   U 8 .   ? 18.798  63.407  -28.423 1.00 56.54  ? 1086 HOH   A O     1 
HETATM 9941  O  O     . HOH   U 8 .   ? 8.379   74.044  -21.686 1.00 45.72  ? 1087 HOH   A O     1 
HETATM 9942  O  O     . HOH   U 8 .   ? 23.581  62.629  -25.388 1.00 39.71  ? 1088 HOH   A O     1 
HETATM 9943  O  O     . HOH   U 8 .   ? 20.844  85.293  -9.953  1.00 48.41  ? 1089 HOH   A O     1 
HETATM 9944  O  O     . HOH   U 8 .   ? 43.684  53.817  -32.897 1.00 39.06  ? 1090 HOH   A O     1 
HETATM 9945  O  O     . HOH   U 8 .   ? 47.559  74.707  -40.191 1.00 52.21  ? 1091 HOH   A O     1 
HETATM 9946  O  O     . HOH   U 8 .   ? 50.321  65.973  -23.158 1.00 33.55  ? 1092 HOH   A O     1 
HETATM 9947  O  O     . HOH   U 8 .   ? 53.460  73.591  -18.987 1.00 33.78  ? 1093 HOH   A O     1 
HETATM 9948  O  O     . HOH   U 8 .   ? 43.139  69.843  -19.687 1.00 39.02  ? 1094 HOH   A O     1 
HETATM 9949  O  O     . HOH   U 8 .   ? 59.743  59.767  -35.273 1.00 45.58  ? 1095 HOH   A O     1 
HETATM 9950  O  O     . HOH   U 8 .   ? 35.043  88.320  -8.447  1.00 49.28  ? 1096 HOH   A O     1 
HETATM 9951  O  O     . HOH   U 8 .   ? 33.665  73.539  -16.185 1.00 39.17  ? 1097 HOH   A O     1 
HETATM 9952  O  O     . HOH   U 8 .   ? 54.885  77.005  -16.805 1.00 32.92  ? 1098 HOH   A O     1 
HETATM 9953  O  O     . HOH   U 8 .   ? 71.449  69.865  -28.453 1.00 49.05  ? 1099 HOH   A O     1 
HETATM 9954  O  O     . HOH   U 8 .   ? 36.827  99.375  -21.021 1.00 53.18  ? 1100 HOH   A O     1 
HETATM 9955  O  O     . HOH   U 8 .   ? 31.769  85.177  -28.798 1.00 48.48  ? 1101 HOH   A O     1 
HETATM 9956  O  O     . HOH   U 8 .   ? 17.820  83.946  -3.480  1.00 41.86  ? 1102 HOH   A O     1 
HETATM 9957  O  O     . HOH   U 8 .   ? 25.825  82.403  -0.124  1.00 62.28  ? 1103 HOH   A O     1 
HETATM 9958  O  O     . HOH   U 8 .   ? 47.469  68.218  -0.397  1.00 37.03  ? 1104 HOH   A O     1 
HETATM 9959  O  O     . HOH   U 8 .   ? 26.733  53.187  -25.744 1.00 42.29  ? 1105 HOH   A O     1 
HETATM 9960  O  O     . HOH   U 8 .   ? 8.644   73.821  -17.239 1.00 47.12  ? 1106 HOH   A O     1 
HETATM 9961  O  O     . HOH   U 8 .   ? 70.383  70.314  -17.909 1.00 57.60  ? 1107 HOH   A O     1 
HETATM 9962  O  O     . HOH   U 8 .   ? 38.651  80.565  -6.306  1.00 38.27  ? 1108 HOH   A O     1 
HETATM 9963  O  O     . HOH   U 8 .   ? 24.985  69.202  -24.963 1.00 43.06  ? 1109 HOH   A O     1 
HETATM 9964  O  O     . HOH   U 8 .   ? 36.784  67.733  -42.640 1.00 42.20  ? 1110 HOH   A O     1 
HETATM 9965  O  O     . HOH   U 8 .   ? 48.711  72.821  -25.152 1.00 28.47  ? 1111 HOH   A O     1 
HETATM 9966  O  O     . HOH   U 8 .   ? 47.108  71.605  -4.240  1.00 35.79  ? 1112 HOH   A O     1 
HETATM 9967  O  O     . HOH   U 8 .   ? 54.637  56.214  -27.716 1.00 39.49  ? 1113 HOH   A O     1 
HETATM 9968  O  O     . HOH   U 8 .   ? 68.872  82.060  -22.745 1.00 50.64  ? 1114 HOH   A O     1 
HETATM 9969  O  O     . HOH   U 8 .   ? 23.893  89.872  -19.398 1.00 51.61  ? 1115 HOH   A O     1 
HETATM 9970  O  O     . HOH   U 8 .   ? 31.613  64.420  -16.686 1.00 36.16  ? 1116 HOH   A O     1 
HETATM 9971  O  O     . HOH   U 8 .   ? 56.665  87.155  -5.654  1.00 43.48  ? 1117 HOH   A O     1 
HETATM 9972  O  O     . HOH   U 8 .   ? 40.422  102.565 -15.743 1.00 48.30  ? 1118 HOH   A O     1 
HETATM 9973  O  O     . HOH   U 8 .   ? 12.929  70.596  -0.989  1.00 30.00  ? 1119 HOH   A O     1 
HETATM 9974  O  O     . HOH   U 8 .   ? 36.005  80.027  -9.169  1.00 50.25  ? 1120 HOH   A O     1 
HETATM 9975  O  O     . HOH   U 8 .   ? 50.772  76.208  -36.810 1.00 44.94  ? 1121 HOH   A O     1 
HETATM 9976  O  O     . HOH   U 8 .   ? 49.443  70.284  -25.773 1.00 31.82  ? 1122 HOH   A O     1 
HETATM 9977  O  O     . HOH   U 8 .   ? 49.408  90.446  1.428   1.00 45.94  ? 1123 HOH   A O     1 
HETATM 9978  O  O     . HOH   U 8 .   ? 65.182  64.883  -20.205 1.00 50.81  ? 1124 HOH   A O     1 
HETATM 9979  O  O     . HOH   U 8 .   ? 29.129  47.514  -20.110 1.00 51.70  ? 1125 HOH   A O     1 
HETATM 9980  O  O     . HOH   U 8 .   ? 40.419  86.691  -30.488 1.00 41.26  ? 1126 HOH   A O     1 
HETATM 9981  O  O     . HOH   U 8 .   ? 19.179  77.673  -28.470 1.00 51.72  ? 1127 HOH   A O     1 
HETATM 9982  O  O     . HOH   U 8 .   ? 30.802  73.423  -14.487 1.00 39.25  ? 1128 HOH   A O     1 
HETATM 9983  O  O     . HOH   U 8 .   ? 40.968  70.385  -13.629 1.00 27.09  ? 1129 HOH   A O     1 
HETATM 9984  O  O     . HOH   U 8 .   ? 32.554  57.374  -32.642 1.00 42.13  ? 1130 HOH   A O     1 
HETATM 9985  O  O     . HOH   U 8 .   ? 52.797  69.144  -20.881 1.00 48.96  ? 1131 HOH   A O     1 
HETATM 9986  O  O     . HOH   U 8 .   ? 48.887  71.966  -22.465 1.00 31.47  ? 1132 HOH   A O     1 
HETATM 9987  O  O     . HOH   U 8 .   ? 26.595  53.950  -8.677  1.00 44.57  ? 1133 HOH   A O     1 
HETATM 9988  O  O     . HOH   U 8 .   ? 57.954  74.908  -35.228 1.00 39.62  ? 1134 HOH   A O     1 
HETATM 9989  O  O     . HOH   U 8 .   ? 36.277  75.895  -17.118 1.00 31.04  ? 1135 HOH   A O     1 
HETATM 9990  O  O     . HOH   U 8 .   ? 54.930  72.569  14.984  1.00 41.65  ? 1136 HOH   A O     1 
HETATM 9991  O  O     . HOH   U 8 .   ? 38.909  74.757  -16.745 1.00 31.16  ? 1137 HOH   A O     1 
HETATM 9992  O  O     . HOH   U 8 .   ? 51.331  97.862  -18.863 1.00 51.61  ? 1138 HOH   A O     1 
HETATM 9993  O  O     . HOH   U 8 .   ? 31.477  79.234  -18.228 1.00 39.40  ? 1139 HOH   A O     1 
HETATM 9994  O  O     . HOH   U 8 .   ? 56.219  79.922  4.391   1.00 38.76  ? 1140 HOH   A O     1 
HETATM 9995  O  O     . HOH   U 8 .   ? 61.186  66.654  -22.757 1.00 40.15  ? 1141 HOH   A O     1 
HETATM 9996  O  O     . HOH   U 8 .   ? 24.088  66.317  -28.165 1.00 43.67  ? 1142 HOH   A O     1 
HETATM 9997  O  O     . HOH   U 8 .   ? 56.769  76.380  -10.287 1.00 44.04  ? 1143 HOH   A O     1 
HETATM 9998  O  O     . HOH   U 8 .   ? 37.867  67.483  -25.974 1.00 29.67  ? 1144 HOH   A O     1 
HETATM 9999  O  O     . HOH   U 8 .   ? 51.953  82.811  -26.994 1.00 42.97  ? 1145 HOH   A O     1 
HETATM 10000 O  O     . HOH   U 8 .   ? 42.859  78.417  -6.843  1.00 32.94  ? 1146 HOH   A O     1 
HETATM 10001 O  O     . HOH   U 8 .   ? 25.230  64.794  -24.999 1.00 30.47  ? 1147 HOH   A O     1 
HETATM 10002 O  O     . HOH   U 8 .   ? 51.327  58.272  27.488  1.00 60.66  ? 1148 HOH   A O     1 
HETATM 10003 O  O     . HOH   U 8 .   ? 27.345  83.203  -15.249 1.00 34.50  ? 1149 HOH   A O     1 
HETATM 10004 O  O     . HOH   U 8 .   ? 66.474  71.822  -12.579 1.00 46.33  ? 1150 HOH   A O     1 
HETATM 10005 O  O     . HOH   U 8 .   ? 12.936  77.300  -7.421  1.00 47.31  ? 1151 HOH   A O     1 
HETATM 10006 O  O     . HOH   U 8 .   ? 39.806  84.808  -3.159  1.00 48.09  ? 1152 HOH   A O     1 
HETATM 10007 O  O     . HOH   U 8 .   ? 59.035  67.438  -28.989 1.00 33.01  ? 1153 HOH   A O     1 
HETATM 10008 O  O     . HOH   U 8 .   ? 18.730  54.524  -26.292 1.00 53.02  ? 1154 HOH   A O     1 
HETATM 10009 O  O     . HOH   U 8 .   ? 46.991  91.890  -29.195 1.00 54.33  ? 1155 HOH   A O     1 
HETATM 10010 O  O     . HOH   U 8 .   ? 56.707  55.898  -26.248 1.00 58.01  ? 1156 HOH   A O     1 
HETATM 10011 O  O     . HOH   U 8 .   ? 50.766  86.347  8.121   1.00 50.49  ? 1157 HOH   A O     1 
HETATM 10012 O  O     . HOH   U 8 .   ? 47.780  68.553  -20.731 1.00 31.57  ? 1158 HOH   A O     1 
HETATM 10013 O  O     . HOH   U 8 .   ? 65.065  57.855  -26.937 1.00 56.38  ? 1159 HOH   A O     1 
HETATM 10014 O  O     . HOH   U 8 .   ? 39.828  95.412  0.817   1.00 63.00  ? 1160 HOH   A O     1 
HETATM 10015 O  O     . HOH   U 8 .   ? 30.629  84.189  -8.820  1.00 43.27  ? 1161 HOH   A O     1 
HETATM 10016 O  O     . HOH   U 8 .   ? 31.583  91.623  -6.628  1.00 56.09  ? 1162 HOH   A O     1 
HETATM 10017 O  O     . HOH   U 8 .   ? 37.758  57.349  -30.063 1.00 39.78  ? 1163 HOH   A O     1 
HETATM 10018 O  O     . HOH   U 8 .   ? 34.260  79.446  -7.133  1.00 38.66  ? 1164 HOH   A O     1 
HETATM 10019 O  O     . HOH   U 8 .   ? 47.952  66.186  -20.066 1.00 38.22  ? 1165 HOH   A O     1 
HETATM 10020 O  O     . HOH   U 8 .   ? 27.951  88.985  -3.477  1.00 62.29  ? 1166 HOH   A O     1 
HETATM 10021 O  O     . HOH   U 8 .   ? 30.906  66.973  -32.814 1.00 40.65  ? 1167 HOH   A O     1 
HETATM 10022 O  O     . HOH   U 8 .   ? 47.204  58.411  6.427   1.00 37.06  ? 1168 HOH   A O     1 
HETATM 10023 O  O     . HOH   U 8 .   ? 22.480  69.064  -24.474 1.00 38.53  ? 1169 HOH   A O     1 
HETATM 10024 O  O     . HOH   U 8 .   ? 33.525  56.986  -18.311 1.00 47.94  ? 1170 HOH   A O     1 
HETATM 10025 O  O     . HOH   U 8 .   ? 27.498  49.444  -22.009 1.00 57.79  ? 1171 HOH   A O     1 
HETATM 10026 O  O     . HOH   U 8 .   ? 58.496  78.800  -38.798 1.00 58.88  ? 1172 HOH   A O     1 
HETATM 10027 O  O     . HOH   U 8 .   ? 27.777  56.555  -32.769 1.00 40.67  ? 1173 HOH   A O     1 
HETATM 10028 O  O     . HOH   U 8 .   ? 37.019  64.330  23.408  1.00 63.42  ? 1174 HOH   A O     1 
HETATM 10029 O  O     . HOH   U 8 .   ? 72.409  70.550  -19.884 1.00 55.08  ? 1175 HOH   A O     1 
HETATM 10030 O  O     . HOH   U 8 .   ? 57.153  74.006  -9.593  1.00 53.66  ? 1176 HOH   A O     1 
HETATM 10031 O  O     . HOH   U 8 .   ? 23.679  84.847  -22.543 1.00 55.03  ? 1177 HOH   A O     1 
HETATM 10032 O  O     . HOH   U 8 .   ? 49.450  72.616  -5.385  1.00 29.28  ? 1178 HOH   A O     1 
HETATM 10033 O  O     . HOH   U 8 .   ? 64.091  83.552  -7.219  1.00 47.62  ? 1179 HOH   A O     1 
HETATM 10034 O  O     . HOH   U 8 .   ? 30.218  92.430  -9.665  1.00 44.92  ? 1180 HOH   A O     1 
HETATM 10035 O  O     . HOH   U 8 .   ? 13.129  73.917  -24.324 1.00 48.77  ? 1181 HOH   A O     1 
HETATM 10036 O  O     . HOH   U 8 .   ? 40.285  57.739  -35.484 1.00 44.17  ? 1182 HOH   A O     1 
HETATM 10037 O  O     . HOH   U 8 .   ? 20.389  55.496  -1.186  1.00 42.84  ? 1183 HOH   A O     1 
HETATM 10038 O  O     . HOH   U 8 .   ? 4.485   69.312  -9.997  1.00 45.56  ? 1184 HOH   A O     1 
HETATM 10039 O  O     . HOH   U 8 .   ? 16.657  75.541  -1.986  1.00 45.08  ? 1185 HOH   A O     1 
HETATM 10040 O  O     . HOH   U 8 .   ? 35.882  83.151  -3.867  1.00 47.13  ? 1186 HOH   A O     1 
HETATM 10041 O  O     . HOH   U 8 .   ? 60.402  66.243  -14.530 1.00 44.14  ? 1187 HOH   A O     1 
HETATM 10042 O  O     . HOH   U 8 .   ? 28.123  68.695  -36.151 1.00 53.64  ? 1188 HOH   A O     1 
HETATM 10043 O  O     . HOH   U 8 .   ? 20.259  66.227  -24.892 1.00 44.32  ? 1189 HOH   A O     1 
HETATM 10044 O  O     . HOH   U 8 .   ? 47.208  59.347  -23.975 1.00 32.38  ? 1190 HOH   A O     1 
HETATM 10045 O  O     . HOH   U 8 .   ? 13.530  83.746  -2.737  1.00 52.99  ? 1191 HOH   A O     1 
HETATM 10046 O  O     . HOH   U 8 .   ? 56.646  75.500  -15.501 1.00 47.61  ? 1192 HOH   A O     1 
HETATM 10047 O  O     . HOH   U 8 .   ? 57.691  57.804  -34.809 1.00 51.58  ? 1193 HOH   A O     1 
HETATM 10048 O  O     . HOH   U 8 .   ? 47.235  87.726  -28.628 1.00 47.08  ? 1194 HOH   A O     1 
HETATM 10049 O  O     . HOH   U 8 .   ? 57.490  89.593  -4.149  1.00 44.87  ? 1195 HOH   A O     1 
HETATM 10050 O  O     . HOH   U 8 .   ? 37.353  58.987  -17.858 1.00 35.38  ? 1196 HOH   A O     1 
HETATM 10051 O  O     . HOH   U 8 .   ? 47.595  58.533  -21.792 1.00 52.61  ? 1197 HOH   A O     1 
HETATM 10052 O  O     . HOH   U 8 .   ? 30.231  68.345  -37.180 1.00 41.46  ? 1198 HOH   A O     1 
HETATM 10053 O  O     . HOH   U 8 .   ? 28.506  45.507  -15.425 1.00 59.66  ? 1199 HOH   A O     1 
HETATM 10054 O  O     . HOH   U 8 .   ? 54.640  83.446  -27.271 1.00 46.72  ? 1200 HOH   A O     1 
HETATM 10055 O  O     . HOH   U 8 .   ? 33.620  89.928  -6.541  1.00 54.94  ? 1201 HOH   A O     1 
HETATM 10056 O  O     . HOH   U 8 .   ? 41.584  103.535 -18.210 1.00 52.63  ? 1202 HOH   A O     1 
HETATM 10057 O  O     . HOH   U 8 .   ? 51.929  71.804  -24.040 1.00 42.92  ? 1203 HOH   A O     1 
HETATM 10058 O  O     . HOH   U 8 .   ? 70.818  84.215  -29.614 1.00 65.68  ? 1204 HOH   A O     1 
HETATM 10059 O  O     . HOH   U 8 .   ? 10.091  65.422  3.607   1.00 62.50  ? 1205 HOH   A O     1 
HETATM 10060 O  O     . HOH   U 8 .   ? 58.252  78.967  5.556   1.00 49.37  ? 1206 HOH   A O     1 
HETATM 10061 O  O     . HOH   U 8 .   ? 55.989  66.973  -8.711  1.00 54.13  ? 1207 HOH   A O     1 
HETATM 10062 O  O     . HOH   U 8 .   ? 18.959  67.929  -25.736 1.00 55.45  ? 1208 HOH   A O     1 
HETATM 10063 O  O     . HOH   U 8 .   ? 58.301  73.493  2.113   1.00 57.25  ? 1209 HOH   A O     1 
HETATM 10064 O  O     . HOH   U 8 .   ? 11.262  63.321  -18.070 1.00 53.93  ? 1210 HOH   A O     1 
HETATM 10065 O  O     . HOH   U 8 .   ? 39.020  58.770  -5.210  1.00 55.43  ? 1211 HOH   A O     1 
HETATM 10066 O  O     . HOH   U 8 .   ? 15.558  67.797  -23.187 1.00 36.21  ? 1212 HOH   A O     1 
HETATM 10067 O  O     . HOH   U 8 .   ? 50.875  84.823  -28.934 1.00 38.73  ? 1213 HOH   A O     1 
HETATM 10068 O  O     . HOH   U 8 .   ? 54.308  70.119  15.675  1.00 42.66  ? 1214 HOH   A O     1 
HETATM 10069 O  O     . HOH   U 8 .   ? 17.877  78.123  -26.360 1.00 41.71  ? 1215 HOH   A O     1 
HETATM 10070 O  O     . HOH   U 8 .   ? 23.973  70.665  -27.096 1.00 49.02  ? 1216 HOH   A O     1 
HETATM 10071 O  O     . HOH   U 8 .   ? 19.482  84.894  -1.850  1.00 52.66  ? 1217 HOH   A O     1 
HETATM 10072 O  O     . HOH   U 8 .   ? 59.721  74.176  4.841   1.00 54.16  ? 1218 HOH   A O     1 
HETATM 10073 O  O     . HOH   U 8 .   ? 48.144  85.190  -28.238 1.00 45.90  ? 1219 HOH   A O     1 
HETATM 10074 O  O     . HOH   U 8 .   ? 52.544  66.128  -21.559 1.00 51.32  ? 1220 HOH   A O     1 
HETATM 10075 O  O     . HOH   U 8 .   ? 41.251  58.119  -6.082  1.00 53.01  ? 1221 HOH   A O     1 
HETATM 10076 O  O     . HOH   V 8 .   ? 2.693   98.963  -64.600 1.00 48.03  ? 301  HOH   E O     1 
HETATM 10077 O  O     . HOH   V 8 .   ? 14.727  92.387  -69.544 1.00 43.53  ? 302  HOH   E O     1 
HETATM 10078 O  O     . HOH   V 8 .   ? -3.810  113.688 -57.398 1.00 60.39  ? 303  HOH   E O     1 
HETATM 10079 O  O     . HOH   V 8 .   ? -1.577  101.244 -61.723 1.00 51.70  ? 304  HOH   E O     1 
HETATM 10080 O  O     . HOH   V 8 .   ? -2.081  104.902 -58.741 1.00 50.14  ? 305  HOH   E O     1 
HETATM 10081 O  O     . HOH   V 8 .   ? 20.112  93.408  -53.045 1.00 27.11  ? 306  HOH   E O     1 
HETATM 10082 O  O     . HOH   V 8 .   ? 3.936   92.654  -60.742 1.00 43.31  ? 307  HOH   E O     1 
HETATM 10083 O  O     . HOH   V 8 .   ? 4.785   96.121  -58.414 1.00 35.10  ? 308  HOH   E O     1 
HETATM 10084 O  O     . HOH   V 8 .   ? 16.152  95.152  -68.204 1.00 41.46  ? 309  HOH   E O     1 
HETATM 10085 O  O     . HOH   V 8 .   ? 26.451  87.348  -55.537 1.00 30.77  ? 310  HOH   E O     1 
HETATM 10086 O  O     . HOH   V 8 .   ? 12.902  90.614  -59.321 1.00 39.16  ? 311  HOH   E O     1 
HETATM 10087 O  O     . HOH   V 8 .   ? 23.675  88.205  -60.785 1.00 35.54  ? 312  HOH   E O     1 
HETATM 10088 O  O     . HOH   V 8 .   ? 15.043  90.661  -61.097 1.00 42.54  ? 313  HOH   E O     1 
HETATM 10089 O  O     . HOH   V 8 .   ? 11.117  98.351  -65.474 1.00 47.82  ? 314  HOH   E O     1 
HETATM 10090 O  O     . HOH   V 8 .   ? 6.528   98.265  -57.344 1.00 41.90  ? 315  HOH   E O     1 
HETATM 10091 O  O     . HOH   V 8 .   ? 27.871  88.250  -58.377 1.00 49.76  ? 316  HOH   E O     1 
HETATM 10092 O  O     . HOH   V 8 .   ? 24.026  93.073  -65.180 1.00 32.32  ? 317  HOH   E O     1 
HETATM 10093 O  O     . HOH   V 8 .   ? 6.557   98.102  -66.890 1.00 40.06  ? 318  HOH   E O     1 
HETATM 10094 O  O     . HOH   V 8 .   ? 6.384   93.700  -59.462 1.00 44.85  ? 319  HOH   E O     1 
HETATM 10095 O  O     . HOH   V 8 .   ? 17.783  87.033  -59.489 1.00 30.97  ? 320  HOH   E O     1 
HETATM 10096 O  O     . HOH   V 8 .   ? 6.827   100.818 -56.260 1.00 44.49  ? 321  HOH   E O     1 
HETATM 10097 O  O     . HOH   V 8 .   ? 21.519  88.837  -60.388 1.00 48.11  ? 322  HOH   E O     1 
HETATM 10098 O  O     . HOH   W 8 .   ? 19.071  105.746 -59.387 1.00 48.36  ? 301  HOH   F O     1 
HETATM 10099 O  O     . HOH   W 8 .   ? 9.215   88.156  -51.884 1.00 45.18  ? 302  HOH   F O     1 
HETATM 10100 O  O     . HOH   W 8 .   ? 4.908   84.347  -50.628 1.00 40.12  ? 303  HOH   F O     1 
HETATM 10101 O  O     . HOH   W 8 .   ? 10.321  91.560  -50.903 1.00 37.39  ? 304  HOH   F O     1 
HETATM 10102 O  O     . HOH   W 8 .   ? 9.153   94.324  -55.114 1.00 43.55  ? 305  HOH   F O     1 
HETATM 10103 O  O     . HOH   W 8 .   ? 10.295  96.578  -50.079 1.00 44.72  ? 306  HOH   F O     1 
HETATM 10104 O  O     . HOH   W 8 .   ? 10.510  88.121  -54.257 1.00 48.42  ? 307  HOH   F O     1 
HETATM 10105 O  O     . HOH   W 8 .   ? 9.605   94.352  -44.600 1.00 34.80  ? 308  HOH   F O     1 
HETATM 10106 O  O     . HOH   W 8 .   ? 18.099  95.244  -52.778 1.00 28.09  ? 309  HOH   F O     1 
HETATM 10107 O  O     . HOH   W 8 .   ? 11.209  85.718  -56.573 1.00 44.68  ? 310  HOH   F O     1 
HETATM 10108 O  O     . HOH   W 8 .   ? 10.059  106.729 -60.770 1.00 48.71  ? 311  HOH   F O     1 
HETATM 10109 O  O     . HOH   W 8 .   ? 5.812   86.586  -50.872 1.00 43.25  ? 312  HOH   F O     1 
HETATM 10110 O  O     . HOH   W 8 .   ? 10.373  95.467  -52.264 1.00 42.48  ? 313  HOH   F O     1 
HETATM 10111 O  O     . HOH   W 8 .   ? 7.809   105.607 -58.706 1.00 47.59  ? 314  HOH   F O     1 
HETATM 10112 O  O     . HOH   W 8 .   ? 8.903   102.351 -56.318 1.00 48.28  ? 315  HOH   F O     1 
HETATM 10113 O  O     . HOH   W 8 .   ? 17.431  106.181 -54.876 1.00 28.23  ? 316  HOH   F O     1 
HETATM 10114 O  O     . HOH   W 8 .   ? 13.090  87.493  -57.450 1.00 43.57  ? 317  HOH   F O     1 
HETATM 10115 O  O     . HOH   W 8 .   ? 15.310  100.433 -61.801 1.00 37.33  ? 318  HOH   F O     1 
HETATM 10116 O  O     . HOH   W 8 .   ? 16.348  99.295  -59.445 1.00 36.13  ? 319  HOH   F O     1 
HETATM 10117 O  O     . HOH   W 8 .   ? 10.010  90.678  -55.676 1.00 32.97  ? 320  HOH   F O     1 
HETATM 10118 O  O     . HOH   W 8 .   ? 16.992  98.642  -56.235 1.00 33.43  ? 321  HOH   F O     1 
HETATM 10119 O  O     . HOH   W 8 .   ? 3.717   109.911 -67.135 1.00 42.66  ? 322  HOH   F O     1 
HETATM 10120 O  O     . HOH   W 8 .   ? 17.254  91.552  -49.728 1.00 28.46  ? 323  HOH   F O     1 
HETATM 10121 O  O     . HOH   W 8 .   ? 7.358   101.556 -67.092 1.00 34.96  ? 324  HOH   F O     1 
HETATM 10122 O  O     . HOH   W 8 .   ? 11.939  103.219 -54.359 1.00 53.52  ? 325  HOH   F O     1 
HETATM 10123 O  O     . HOH   W 8 .   ? 13.409  84.660  -60.498 1.00 36.54  ? 326  HOH   F O     1 
HETATM 10124 O  O     . HOH   W 8 .   ? 8.810   98.343  -54.172 1.00 40.29  ? 327  HOH   F O     1 
HETATM 10125 O  O     . HOH   W 8 .   ? 7.503   96.450  -55.079 1.00 48.34  ? 328  HOH   F O     1 
HETATM 10126 O  O     . HOH   W 8 .   ? 19.266  108.970 -58.000 1.00 45.06  ? 329  HOH   F O     1 
HETATM 10127 O  O     . HOH   W 8 .   ? 9.140   93.376  -52.260 1.00 45.61  ? 330  HOH   F O     1 
HETATM 10128 O  O     . HOH   X 8 .   ? 10.419  110.618 -21.431 1.00 58.01  ? 1001 HOH   D O     1 
HETATM 10129 O  O     . HOH   X 8 .   ? 43.543  94.898  -35.600 1.00 55.05  ? 1002 HOH   D O     1 
HETATM 10130 O  O     . HOH   X 8 .   ? 34.409  118.462 -52.755 1.00 42.41  ? 1003 HOH   D O     1 
HETATM 10131 O  O     . HOH   X 8 .   ? 26.663  101.363 -30.552 1.00 52.35  ? 1004 HOH   D O     1 
HETATM 10132 O  O     . HOH   X 8 .   ? 8.180   77.139  -28.524 1.00 52.35  ? 1005 HOH   D O     1 
HETATM 10133 O  O     . HOH   X 8 .   ? 22.742  86.249  -57.361 1.00 26.84  ? 1006 HOH   D O     1 
HETATM 10134 O  O     . HOH   X 8 .   ? 29.848  103.397 -47.763 1.00 33.94  ? 1007 HOH   D O     1 
HETATM 10135 O  O     . HOH   X 8 .   ? 12.500  63.539  -45.812 1.00 48.08  ? 1008 HOH   D O     1 
HETATM 10136 O  O     . HOH   X 8 .   ? 3.037   71.046  -43.631 1.00 55.41  ? 1009 HOH   D O     1 
HETATM 10137 O  O     . HOH   X 8 .   ? 27.072  89.755  -52.948 1.00 48.25  ? 1010 HOH   D O     1 
HETATM 10138 O  O     . HOH   X 8 .   ? 35.647  106.403 -42.517 1.00 54.21  ? 1011 HOH   D O     1 
HETATM 10139 O  O     . HOH   X 8 .   ? 22.540  86.093  -48.182 1.00 26.99  ? 1012 HOH   D O     1 
HETATM 10140 O  O     . HOH   X 8 .   ? 19.661  89.580  -20.229 1.00 48.81  ? 1013 HOH   D O     1 
HETATM 10141 O  O     . HOH   X 8 .   ? 35.467  84.866  -36.475 1.00 47.68  ? 1014 HOH   D O     1 
HETATM 10142 O  O     . HOH   X 8 .   ? 16.614  67.521  -40.761 1.00 27.45  ? 1015 HOH   D O     1 
HETATM 10143 O  O     . HOH   X 8 .   ? 29.098  91.835  -29.673 1.00 46.89  ? 1016 HOH   D O     1 
HETATM 10144 O  O     . HOH   X 8 .   ? 32.786  79.454  -38.322 1.00 37.34  ? 1017 HOH   D O     1 
HETATM 10145 O  O     . HOH   X 8 .   ? 8.734   78.329  -34.661 1.00 43.20  ? 1018 HOH   D O     1 
HETATM 10146 O  O     . HOH   X 8 .   ? 26.806  115.585 -56.768 1.00 42.39  ? 1019 HOH   D O     1 
HETATM 10147 O  O     . HOH   X 8 .   ? -0.251  83.673  -48.043 1.00 40.63  ? 1020 HOH   D O     1 
HETATM 10148 O  O     . HOH   X 8 .   ? 27.529  102.872 -78.860 1.00 42.33  ? 1021 HOH   D O     1 
HETATM 10149 O  O     . HOH   X 8 .   ? 16.156  78.077  -37.095 1.00 45.40  ? 1022 HOH   D O     1 
HETATM 10150 O  O     . HOH   X 8 .   ? 4.568   93.063  -30.692 1.00 37.31  ? 1023 HOH   D O     1 
HETATM 10151 O  O     . HOH   X 8 .   ? 20.749  63.160  -46.696 1.00 59.34  ? 1024 HOH   D O     1 
HETATM 10152 O  O     . HOH   X 8 .   ? 1.902   84.980  -44.119 1.00 54.93  ? 1025 HOH   D O     1 
HETATM 10153 O  O     . HOH   X 8 .   ? 38.802  81.547  -39.302 1.00 42.70  ? 1026 HOH   D O     1 
HETATM 10154 O  O     . HOH   X 8 .   ? 16.420  67.080  -58.943 1.00 41.97  ? 1027 HOH   D O     1 
HETATM 10155 O  O     . HOH   X 8 .   ? 1.275   75.031  -42.828 1.00 40.30  ? 1028 HOH   D O     1 
HETATM 10156 O  O     . HOH   X 8 .   ? 0.206   79.470  -36.442 1.00 42.24  ? 1029 HOH   D O     1 
HETATM 10157 O  O     . HOH   X 8 .   ? 8.371   88.491  -30.224 1.00 42.62  ? 1030 HOH   D O     1 
HETATM 10158 O  O     . HOH   X 8 .   ? 10.189  66.583  -39.894 1.00 36.36  ? 1031 HOH   D O     1 
HETATM 10159 O  O     . HOH   X 8 .   ? 30.493  98.748  -33.117 1.00 36.40  ? 1032 HOH   D O     1 
HETATM 10160 O  O     . HOH   X 8 .   ? 13.101  89.135  -34.439 1.00 26.49  ? 1033 HOH   D O     1 
HETATM 10161 O  O     . HOH   X 8 .   ? 24.319  69.357  -58.154 1.00 48.99  ? 1034 HOH   D O     1 
HETATM 10162 O  O     . HOH   X 8 .   ? 3.504   90.749  -36.796 1.00 38.09  ? 1035 HOH   D O     1 
HETATM 10163 O  O     . HOH   X 8 .   ? 18.628  94.439  -40.079 1.00 26.74  ? 1036 HOH   D O     1 
HETATM 10164 O  O     . HOH   X 8 .   ? 14.328  106.329 -52.272 1.00 34.44  ? 1037 HOH   D O     1 
HETATM 10165 O  O     . HOH   X 8 .   ? 36.241  103.600 -52.744 1.00 31.40  ? 1038 HOH   D O     1 
HETATM 10166 O  O     . HOH   X 8 .   ? 14.610  89.544  -19.571 1.00 42.73  ? 1039 HOH   D O     1 
HETATM 10167 O  O     . HOH   X 8 .   ? 29.558  68.089  -40.036 1.00 53.82  ? 1040 HOH   D O     1 
HETATM 10168 O  O     . HOH   X 8 .   ? 21.554  100.631 -22.057 1.00 52.70  ? 1041 HOH   D O     1 
HETATM 10169 O  O     . HOH   X 8 .   ? 26.084  110.550 -52.138 1.00 40.12  ? 1042 HOH   D O     1 
HETATM 10170 O  O     . HOH   X 8 .   ? 31.752  107.044 -75.021 1.00 43.67  ? 1043 HOH   D O     1 
HETATM 10171 O  O     . HOH   X 8 .   ? 21.903  102.605 -32.565 1.00 29.44  ? 1044 HOH   D O     1 
HETATM 10172 O  O     . HOH   X 8 .   ? 9.048   93.450  -42.112 1.00 38.55  ? 1045 HOH   D O     1 
HETATM 10173 O  O     . HOH   X 8 .   ? 37.373  91.196  -33.312 1.00 38.92  ? 1046 HOH   D O     1 
HETATM 10174 O  O     . HOH   X 8 .   ? 5.605   87.600  -41.943 1.00 38.47  ? 1047 HOH   D O     1 
HETATM 10175 O  O     . HOH   X 8 .   ? 11.067  80.294  -29.737 1.00 44.85  ? 1048 HOH   D O     1 
HETATM 10176 O  O     . HOH   X 8 .   ? 31.836  93.329  -70.044 1.00 51.77  ? 1049 HOH   D O     1 
HETATM 10177 O  O     . HOH   X 8 .   ? 20.139  103.324 -34.669 1.00 30.54  ? 1050 HOH   D O     1 
HETATM 10178 O  O     . HOH   X 8 .   ? 18.852  104.284 -42.975 1.00 39.84  ? 1051 HOH   D O     1 
HETATM 10179 O  O     . HOH   X 8 .   ? 16.891  124.358 -33.833 1.00 47.63  ? 1052 HOH   D O     1 
HETATM 10180 O  O     . HOH   X 8 .   ? 10.125  73.427  -51.292 1.00 37.52  ? 1053 HOH   D O     1 
HETATM 10181 O  O     . HOH   X 8 .   ? 33.738  73.860  -47.544 1.00 45.28  ? 1054 HOH   D O     1 
HETATM 10182 O  O     . HOH   X 8 .   ? 9.983   120.122 -37.867 1.00 51.68  ? 1055 HOH   D O     1 
HETATM 10183 O  O     . HOH   X 8 .   ? 14.269  85.332  -27.157 1.00 30.92  ? 1056 HOH   D O     1 
HETATM 10184 O  O     . HOH   X 8 .   ? 6.251   97.966  -21.488 1.00 41.10  ? 1057 HOH   D O     1 
HETATM 10185 O  O     . HOH   X 8 .   ? 17.043  72.781  -55.906 1.00 46.48  ? 1058 HOH   D O     1 
HETATM 10186 O  O     . HOH   X 8 .   ? 26.092  68.827  -64.091 1.00 45.12  ? 1059 HOH   D O     1 
HETATM 10187 O  O     . HOH   X 8 .   ? 34.065  110.992 -70.001 1.00 43.51  ? 1060 HOH   D O     1 
HETATM 10188 O  O     . HOH   X 8 .   ? 40.409  84.081  -54.149 1.00 53.67  ? 1061 HOH   D O     1 
HETATM 10189 O  O     . HOH   X 8 .   ? 0.830   96.731  -29.318 1.00 37.80  ? 1062 HOH   D O     1 
HETATM 10190 O  O     . HOH   X 8 .   ? 14.920  102.165 -37.825 1.00 33.71  ? 1063 HOH   D O     1 
HETATM 10191 O  O     . HOH   X 8 .   ? 7.007   89.523  -38.150 1.00 31.35  ? 1064 HOH   D O     1 
HETATM 10192 O  O     . HOH   X 8 .   ? 5.200   99.073  -36.209 1.00 32.57  ? 1065 HOH   D O     1 
HETATM 10193 O  O     . HOH   X 8 .   ? 9.300   83.437  -26.402 1.00 55.42  ? 1066 HOH   D O     1 
HETATM 10194 O  O     . HOH   X 8 .   ? 18.520  95.986  -50.317 1.00 30.75  ? 1067 HOH   D O     1 
HETATM 10195 O  O     . HOH   X 8 .   ? 10.386  104.416 -77.759 1.00 42.77  ? 1068 HOH   D O     1 
HETATM 10196 O  O     . HOH   X 8 .   ? 6.795   112.702 -26.950 1.00 45.80  ? 1069 HOH   D O     1 
HETATM 10197 O  O     . HOH   X 8 .   ? 22.454  109.096 -49.414 1.00 43.02  ? 1070 HOH   D O     1 
HETATM 10198 O  O     . HOH   X 8 .   ? 9.803   73.062  -55.719 1.00 35.65  ? 1071 HOH   D O     1 
HETATM 10199 O  O     . HOH   X 8 .   ? 16.521  105.714 -41.336 1.00 43.72  ? 1072 HOH   D O     1 
HETATM 10200 O  O     . HOH   X 8 .   ? 23.219  110.290 -24.080 1.00 42.18  ? 1073 HOH   D O     1 
HETATM 10201 O  O     . HOH   X 8 .   ? 32.142  84.748  -33.353 1.00 49.28  ? 1074 HOH   D O     1 
HETATM 10202 O  O     . HOH   X 8 .   ? 16.640  79.973  -64.462 1.00 34.79  ? 1075 HOH   D O     1 
HETATM 10203 O  O     . HOH   X 8 .   ? 0.906   107.163 -32.512 1.00 47.56  ? 1076 HOH   D O     1 
HETATM 10204 O  O     . HOH   X 8 .   ? 37.635  96.155  -29.646 1.00 52.28  ? 1077 HOH   D O     1 
HETATM 10205 O  O     . HOH   X 8 .   ? 30.077  82.588  -64.124 1.00 62.43  ? 1078 HOH   D O     1 
HETATM 10206 O  O     . HOH   X 8 .   ? 18.693  100.091 -57.985 1.00 36.53  ? 1079 HOH   D O     1 
HETATM 10207 O  O     . HOH   X 8 .   ? 21.064  61.333  -40.560 1.00 49.61  ? 1080 HOH   D O     1 
HETATM 10208 O  O     . HOH   X 8 .   ? 17.192  102.495 -36.338 1.00 31.96  ? 1081 HOH   D O     1 
HETATM 10209 O  O     . HOH   X 8 .   ? 20.911  80.092  -29.206 1.00 54.39  ? 1082 HOH   D O     1 
HETATM 10210 O  O     . HOH   X 8 .   ? -2.265  76.270  -34.652 1.00 54.50  ? 1083 HOH   D O     1 
HETATM 10211 O  O     . HOH   X 8 .   ? 20.698  106.446 -43.263 1.00 31.61  ? 1084 HOH   D O     1 
HETATM 10212 O  O     . HOH   X 8 .   ? 12.969  103.279 -38.992 1.00 33.80  ? 1085 HOH   D O     1 
HETATM 10213 O  O     . HOH   X 8 .   ? 27.591  91.621  -55.821 1.00 37.40  ? 1086 HOH   D O     1 
HETATM 10214 O  O     . HOH   X 8 .   ? 16.790  96.089  -42.547 1.00 41.22  ? 1087 HOH   D O     1 
HETATM 10215 O  O     . HOH   X 8 .   ? 31.817  96.471  -33.456 1.00 37.38  ? 1088 HOH   D O     1 
HETATM 10216 O  O     . HOH   X 8 .   ? 16.111  109.677 -41.798 1.00 47.38  ? 1089 HOH   D O     1 
HETATM 10217 O  O     . HOH   X 8 .   ? 16.204  83.498  -49.756 1.00 27.33  ? 1090 HOH   D O     1 
HETATM 10218 O  O     . HOH   X 8 .   ? 19.432  78.211  -49.426 1.00 48.28  ? 1091 HOH   D O     1 
HETATM 10219 O  O     . HOH   X 8 .   ? 17.510  83.950  -63.262 1.00 47.70  ? 1092 HOH   D O     1 
HETATM 10220 O  O     . HOH   X 8 .   ? 46.268  89.804  -41.092 1.00 48.21  ? 1093 HOH   D O     1 
HETATM 10221 O  O     . HOH   X 8 .   ? 22.767  79.811  -31.501 1.00 45.39  ? 1094 HOH   D O     1 
HETATM 10222 O  O     . HOH   X 8 .   ? 11.218  98.341  -45.780 1.00 47.84  ? 1095 HOH   D O     1 
HETATM 10223 O  O     . HOH   X 8 .   ? 16.463  78.916  -32.751 1.00 38.50  ? 1096 HOH   D O     1 
HETATM 10224 O  O     . HOH   X 8 .   ? 8.855   82.418  -73.867 1.00 71.45  ? 1097 HOH   D O     1 
HETATM 10225 O  O     . HOH   X 8 .   ? 21.999  110.933 -26.888 1.00 44.18  ? 1098 HOH   D O     1 
HETATM 10226 O  O     . HOH   X 8 .   ? 11.346  84.535  -45.564 1.00 34.28  ? 1099 HOH   D O     1 
HETATM 10227 O  O     . HOH   X 8 .   ? 4.761   75.911  -52.207 1.00 42.60  ? 1100 HOH   D O     1 
HETATM 10228 O  O     . HOH   X 8 .   ? 16.191  79.438  -67.241 1.00 43.57  ? 1101 HOH   D O     1 
HETATM 10229 O  O     . HOH   X 8 .   ? 31.101  70.740  -58.751 1.00 40.80  ? 1102 HOH   D O     1 
HETATM 10230 O  O     . HOH   X 8 .   ? 20.752  86.655  -45.904 1.00 37.90  ? 1103 HOH   D O     1 
HETATM 10231 O  O     . HOH   X 8 .   ? 9.737   76.622  -36.766 1.00 41.31  ? 1104 HOH   D O     1 
HETATM 10232 O  O     . HOH   X 8 .   ? 24.071  107.853 -45.478 1.00 33.75  ? 1105 HOH   D O     1 
HETATM 10233 O  O     . HOH   X 8 .   ? 23.287  124.767 -28.483 1.00 53.59  ? 1106 HOH   D O     1 
HETATM 10234 O  O     . HOH   X 8 .   ? 1.003   79.628  -53.445 1.00 41.72  ? 1107 HOH   D O     1 
HETATM 10235 O  O     . HOH   X 8 .   ? 17.409  93.963  -48.531 1.00 26.61  ? 1108 HOH   D O     1 
HETATM 10236 O  O     . HOH   X 8 .   ? -0.686  76.625  -65.805 1.00 67.68  ? 1109 HOH   D O     1 
HETATM 10237 O  O     . HOH   X 8 .   ? 21.441  111.799 -59.295 1.00 50.51  ? 1110 HOH   D O     1 
HETATM 10238 O  O     . HOH   X 8 .   ? 28.519  63.591  -45.237 1.00 57.12  ? 1111 HOH   D O     1 
HETATM 10239 O  O     . HOH   X 8 .   ? 3.307   107.608 -34.358 1.00 38.73  ? 1112 HOH   D O     1 
HETATM 10240 O  O     . HOH   X 8 .   ? 28.644  85.682  -55.703 1.00 47.30  ? 1113 HOH   D O     1 
HETATM 10241 O  O     . HOH   X 8 .   ? 21.796  91.864  -45.482 1.00 28.14  ? 1114 HOH   D O     1 
HETATM 10242 O  O     . HOH   X 8 .   ? 32.344  73.876  -52.155 1.00 52.44  ? 1115 HOH   D O     1 
HETATM 10243 O  O     . HOH   X 8 .   ? 17.438  123.366 -44.515 1.00 56.31  ? 1116 HOH   D O     1 
HETATM 10244 O  O     . HOH   X 8 .   ? 4.458   85.599  -29.418 1.00 40.90  ? 1117 HOH   D O     1 
HETATM 10245 O  O     . HOH   X 8 .   ? 37.524  102.374 -63.584 1.00 45.18  ? 1118 HOH   D O     1 
HETATM 10246 O  O     . HOH   X 8 .   ? 49.082  94.415  -49.464 1.00 56.70  ? 1119 HOH   D O     1 
HETATM 10247 O  O     . HOH   X 8 .   ? 2.291   100.463 -69.882 1.00 51.92  ? 1120 HOH   D O     1 
HETATM 10248 O  O     . HOH   X 8 .   ? 23.170  103.677 -25.323 1.00 44.39  ? 1121 HOH   D O     1 
HETATM 10249 O  O     . HOH   X 8 .   ? 18.934  101.854 -39.725 1.00 31.11  ? 1122 HOH   D O     1 
HETATM 10250 O  O     . HOH   X 8 .   ? 11.844  118.149 -41.802 1.00 52.69  ? 1123 HOH   D O     1 
HETATM 10251 O  O     . HOH   X 8 .   ? 33.639  93.477  -31.663 1.00 40.58  ? 1124 HOH   D O     1 
HETATM 10252 O  O     . HOH   X 8 .   ? 14.107  99.632  -69.178 1.00 39.63  ? 1125 HOH   D O     1 
HETATM 10253 O  O     . HOH   X 8 .   ? 34.223  109.639 -56.549 1.00 46.24  ? 1126 HOH   D O     1 
HETATM 10254 O  O     . HOH   X 8 .   ? 21.049  117.973 -52.227 1.00 54.36  ? 1127 HOH   D O     1 
HETATM 10255 O  O     . HOH   X 8 .   ? 30.216  80.369  -46.975 1.00 33.28  ? 1128 HOH   D O     1 
HETATM 10256 O  O     . HOH   X 8 .   ? 40.571  89.410  -57.576 1.00 45.42  ? 1129 HOH   D O     1 
HETATM 10257 O  O     . HOH   X 8 .   ? 44.683  104.430 -43.287 1.00 50.72  ? 1130 HOH   D O     1 
HETATM 10258 O  O     . HOH   X 8 .   ? 19.834  101.792 -36.945 1.00 29.68  ? 1131 HOH   D O     1 
HETATM 10259 O  O     . HOH   X 8 .   ? 49.650  93.443  -46.558 1.00 45.72  ? 1132 HOH   D O     1 
HETATM 10260 O  O     . HOH   X 8 .   ? 22.841  89.270  -45.091 1.00 28.66  ? 1133 HOH   D O     1 
HETATM 10261 O  O     . HOH   X 8 .   ? 23.412  109.765 -51.896 1.00 38.90  ? 1134 HOH   D O     1 
HETATM 10262 O  O     . HOH   X 8 .   ? 1.626   71.706  -35.943 1.00 50.20  ? 1135 HOH   D O     1 
HETATM 10263 O  O     . HOH   X 8 .   ? 14.906  112.994 -50.078 1.00 52.00  ? 1136 HOH   D O     1 
HETATM 10264 O  O     . HOH   X 8 .   ? 14.491  90.835  -36.272 1.00 29.23  ? 1137 HOH   D O     1 
HETATM 10265 O  O     . HOH   X 8 .   ? 18.749  119.388 -49.554 1.00 51.23  ? 1138 HOH   D O     1 
HETATM 10266 O  O     . HOH   X 8 .   ? 11.890  78.210  -37.116 1.00 34.20  ? 1139 HOH   D O     1 
HETATM 10267 O  O     . HOH   X 8 .   ? 13.110  100.949 -41.966 1.00 37.52  ? 1140 HOH   D O     1 
HETATM 10268 O  O     . HOH   X 8 .   ? 17.579  65.907  -61.079 1.00 51.08  ? 1141 HOH   D O     1 
HETATM 10269 O  O     . HOH   X 8 .   ? 15.538  100.711 -41.421 1.00 33.63  ? 1142 HOH   D O     1 
HETATM 10270 O  O     . HOH   X 8 .   ? 13.683  114.175 -39.416 1.00 40.57  ? 1143 HOH   D O     1 
HETATM 10271 O  O     . HOH   X 8 .   ? -5.478  82.018  -42.206 1.00 53.26  ? 1144 HOH   D O     1 
HETATM 10272 O  O     . HOH   X 8 .   ? 39.620  83.357  -51.890 1.00 42.76  ? 1145 HOH   D O     1 
HETATM 10273 O  O     . HOH   X 8 .   ? 27.052  109.286 -66.513 1.00 38.40  ? 1146 HOH   D O     1 
HETATM 10274 O  O     . HOH   X 8 .   ? 35.286  88.132  -53.907 1.00 53.94  ? 1147 HOH   D O     1 
HETATM 10275 O  O     . HOH   X 8 .   ? 25.439  95.813  -55.340 1.00 34.59  ? 1148 HOH   D O     1 
HETATM 10276 O  O     . HOH   X 8 .   ? 20.536  83.815  -47.582 1.00 41.80  ? 1149 HOH   D O     1 
HETATM 10277 O  O     . HOH   X 8 .   ? 31.829  92.868  -59.043 1.00 47.15  ? 1150 HOH   D O     1 
HETATM 10278 O  O     . HOH   X 8 .   ? 31.845  76.384  -39.517 1.00 54.35  ? 1151 HOH   D O     1 
HETATM 10279 O  O     . HOH   X 8 .   ? 31.250  83.685  -53.281 1.00 44.21  ? 1152 HOH   D O     1 
HETATM 10280 O  O     . HOH   X 8 .   ? 3.575   80.685  -29.470 1.00 37.58  ? 1153 HOH   D O     1 
HETATM 10281 O  O     . HOH   X 8 .   ? 41.587  109.386 -54.711 1.00 56.68  ? 1154 HOH   D O     1 
HETATM 10282 O  O     . HOH   X 8 .   ? 24.368  65.974  -54.681 1.00 43.71  ? 1155 HOH   D O     1 
HETATM 10283 O  O     . HOH   X 8 .   ? -3.444  80.425  -40.116 1.00 53.86  ? 1156 HOH   D O     1 
HETATM 10284 O  O     . HOH   X 8 .   ? 17.673  76.915  -34.957 1.00 46.62  ? 1157 HOH   D O     1 
HETATM 10285 O  O     . HOH   X 8 .   ? 4.484   90.647  -32.099 1.00 41.02  ? 1158 HOH   D O     1 
HETATM 10286 O  O     . HOH   X 8 .   ? 38.576  84.622  -55.663 1.00 51.67  ? 1159 HOH   D O     1 
HETATM 10287 O  O     . HOH   X 8 .   ? 11.349  89.986  -85.537 1.00 60.48  ? 1160 HOH   D O     1 
HETATM 10288 O  O     . HOH   X 8 .   ? 13.192  73.388  -37.373 1.00 50.19  ? 1161 HOH   D O     1 
HETATM 10289 O  O     . HOH   X 8 .   ? 14.053  83.987  -29.309 1.00 37.68  ? 1162 HOH   D O     1 
HETATM 10290 O  O     . HOH   X 8 .   ? 20.789  66.026  -37.823 1.00 43.35  ? 1163 HOH   D O     1 
HETATM 10291 O  O     . HOH   X 8 .   ? 4.728   93.265  -26.598 1.00 48.71  ? 1164 HOH   D O     1 
HETATM 10292 O  O     . HOH   X 8 .   ? 14.465  111.894 -33.278 1.00 35.52  ? 1165 HOH   D O     1 
HETATM 10293 O  O     . HOH   X 8 .   ? 22.611  109.711 -46.638 1.00 46.41  ? 1166 HOH   D O     1 
HETATM 10294 O  O     . HOH   X 8 .   ? 19.568  102.281 -56.797 1.00 29.15  ? 1167 HOH   D O     1 
HETATM 10295 O  O     . HOH   X 8 .   ? 17.677  105.465 -69.964 1.00 46.91  ? 1168 HOH   D O     1 
HETATM 10296 O  O     . HOH   X 8 .   ? 11.781  120.588 -33.994 1.00 50.32  ? 1169 HOH   D O     1 
HETATM 10297 O  O     . HOH   X 8 .   ? 38.408  108.963 -52.438 1.00 40.15  ? 1170 HOH   D O     1 
HETATM 10298 O  O     . HOH   X 8 .   ? 5.991   90.174  -44.245 1.00 34.83  ? 1171 HOH   D O     1 
HETATM 10299 O  O     . HOH   X 8 .   ? 26.642  121.376 -42.679 1.00 42.31  ? 1172 HOH   D O     1 
HETATM 10300 O  O     . HOH   X 8 .   ? 30.644  117.132 -54.979 1.00 50.12  ? 1173 HOH   D O     1 
HETATM 10301 O  O     . HOH   X 8 .   ? 21.148  110.303 -52.507 1.00 55.39  ? 1174 HOH   D O     1 
HETATM 10302 O  O     . HOH   X 8 .   ? 22.653  69.674  -60.084 1.00 45.47  ? 1175 HOH   D O     1 
HETATM 10303 O  O     . HOH   X 8 .   ? 30.899  83.104  -57.305 1.00 45.61  ? 1176 HOH   D O     1 
HETATM 10304 O  O     . HOH   X 8 .   ? 2.424   73.340  -61.041 1.00 46.07  ? 1177 HOH   D O     1 
HETATM 10305 O  O     . HOH   X 8 .   ? 47.735  101.731 -42.211 1.00 62.14  ? 1178 HOH   D O     1 
HETATM 10306 O  O     . HOH   X 8 .   ? 36.171  76.120  -46.252 1.00 50.50  ? 1179 HOH   D O     1 
HETATM 10307 O  O     . HOH   X 8 .   ? 25.554  111.322 -23.457 1.00 56.46  ? 1180 HOH   D O     1 
HETATM 10308 O  O     . HOH   X 8 .   ? 34.501  102.419 -42.494 1.00 41.01  ? 1181 HOH   D O     1 
HETATM 10309 O  O     . HOH   X 8 .   ? 6.324   100.142 -38.111 1.00 31.50  ? 1182 HOH   D O     1 
HETATM 10310 O  O     . HOH   X 8 .   ? -7.524  81.366  -46.919 1.00 55.78  ? 1183 HOH   D O     1 
HETATM 10311 O  O     . HOH   X 8 .   ? 13.238  113.402 -47.748 1.00 45.88  ? 1184 HOH   D O     1 
HETATM 10312 O  O     . HOH   X 8 .   ? 5.290   100.347 -68.406 1.00 41.17  ? 1185 HOH   D O     1 
HETATM 10313 O  O     . HOH   X 8 .   ? 47.102  100.670 -56.407 1.00 63.72  ? 1186 HOH   D O     1 
HETATM 10314 O  O     . HOH   X 8 .   ? 15.408  83.218  -25.085 1.00 43.02  ? 1187 HOH   D O     1 
HETATM 10315 O  O     . HOH   X 8 .   ? 33.653  107.070 -40.906 1.00 50.45  ? 1188 HOH   D O     1 
HETATM 10316 O  O     . HOH   X 8 .   ? 39.313  87.217  -57.378 1.00 57.96  ? 1189 HOH   D O     1 
HETATM 10317 O  O     . HOH   X 8 .   ? 16.362  95.949  -87.491 1.00 51.02  ? 1190 HOH   D O     1 
HETATM 10318 O  O     . HOH   X 8 .   ? 15.036  71.960  -36.446 1.00 53.86  ? 1191 HOH   D O     1 
HETATM 10319 O  O     . HOH   X 8 .   ? 31.164  123.697 -32.598 1.00 68.57  ? 1192 HOH   D O     1 
HETATM 10320 O  O     . HOH   X 8 .   ? 1.076   105.439 -38.366 1.00 63.79  ? 1193 HOH   D O     1 
HETATM 10321 O  O     . HOH   X 8 .   ? 13.971  97.331  -67.856 1.00 49.62  ? 1194 HOH   D O     1 
HETATM 10322 O  O     . HOH   X 8 .   ? 18.770  104.843 -38.201 1.00 44.82  ? 1195 HOH   D O     1 
HETATM 10323 O  O     . HOH   X 8 .   ? 37.121  86.622  -55.843 1.00 48.28  ? 1196 HOH   D O     1 
HETATM 10324 O  O     . HOH   X 8 .   ? 7.861   67.433  -38.369 1.00 45.91  ? 1197 HOH   D O     1 
HETATM 10325 O  O     . HOH   X 8 .   ? 29.678  83.061  -31.252 1.00 52.20  ? 1198 HOH   D O     1 
HETATM 10326 O  O     . HOH   X 8 .   ? 14.789  68.563  -38.979 1.00 37.06  ? 1199 HOH   D O     1 
HETATM 10327 O  O     . HOH   X 8 .   ? 11.692  106.895 -52.585 1.00 55.52  ? 1200 HOH   D O     1 
HETATM 10328 O  O     . HOH   X 8 .   ? 13.753  108.496 -53.769 1.00 59.83  ? 1201 HOH   D O     1 
HETATM 10329 O  O     . HOH   X 8 .   ? 5.772   92.135  -56.826 1.00 52.10  ? 1202 HOH   D O     1 
HETATM 10330 O  O     . HOH   X 8 .   ? 25.172  70.964  -35.728 1.00 43.55  ? 1203 HOH   D O     1 
HETATM 10331 O  O     . HOH   X 8 .   ? 12.221  121.067 -36.544 1.00 54.69  ? 1204 HOH   D O     1 
HETATM 10332 O  O     . HOH   X 8 .   ? 31.886  72.482  -60.367 1.00 55.19  ? 1205 HOH   D O     1 
HETATM 10333 O  O     . HOH   X 8 .   ? 1.263   102.729 -38.858 1.00 49.90  ? 1206 HOH   D O     1 
HETATM 10334 O  O     . HOH   X 8 .   ? 30.601  99.461  -30.292 1.00 47.60  ? 1207 HOH   D O     1 
HETATM 10335 O  O     . HOH   X 8 .   ? -2.470  76.550  -64.193 1.00 63.97  ? 1208 HOH   D O     1 
HETATM 10336 O  O     . HOH   X 8 .   ? 5.153   94.226  -56.116 1.00 51.76  ? 1209 HOH   D O     1 
# 
