data_8X6X
# 
_entry.id   8X6X 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8X6X         pdb_00008x6x 10.2210/pdb8x6x/pdb 
WWPDB D_1300042710 ?            ?                   
EMDB  EMD-38093    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8X6X 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of the multidrug efflux pump EfpA from M. tuberculosis complexed with lipids' 
_pdbx_database_related.db_id          EMD-38093 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gaofeng@tib.cas.cn 
_pdbx_contact_author.name_first         Feng 
_pdbx_contact_author.name_last          Gao 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0670-010X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Gao, F.'   1 0000-0002-0670-010X 
'Zhang, X.' 2 0000-0001-5073-2582 
'Li, D.'    3 0000-0002-7967-1581 
'Ma, X.'    4 0009-0006-0458-5132 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure of the multidrug efflux pump EfpA from M. tuberculosis complexed with lipids' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Gao, F.'   1 0000-0002-0670-010X 
primary 'Zhang, X.' 2 0000-0001-5073-2582 
primary 'Li, D.'    3 0000-0002-7967-1581 
primary 'Ma, X.'    4 0009-0006-0458-5132 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Uncharacterized MFS-type transporter EfpA'                                                                 
59671.445 2 ? ? ? ? 
2 non-polymer syn '[(2~{R})-1-[(9~{Z},12~{Z},15~{E})-octadeca-9,12,15-trienoyl]oxy-3-phosphonooxy-propan-2-yl] nonadecanoate' 
712.977   2 ? ? ? ? 
3 non-polymer syn '[(2~{S})-1-dodecanoyloxy-3-phosphonooxy-propan-2-yl] tridecanoate'                                         
550.705   1 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQ
NELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASP
TGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA
TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVM
FSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPN
LVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL
AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGELAAAENLYFQGLWSHPQFEKGGGSGGGSGGS
AWSHPQFEK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQ
NELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASP
TGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA
TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVM
FSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPN
LVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL
AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGELAAAENLYFQGLWSHPQFEKGGGSGGGSGGS
AWSHPQFEK
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '[(2~{R})-1-[(9~{Z},12~{Z},15~{E})-octadeca-9,12,15-trienoyl]oxy-3-phosphonooxy-propan-2-yl] nonadecanoate' Y86 
3 '[(2~{S})-1-dodecanoyloxy-3-phosphonooxy-propan-2-yl] tridecanoate'                                         Y8F 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   THR n 
1 3   ALA n 
1 4   LEU n 
1 5   ASN n 
1 6   ASP n 
1 7   THR n 
1 8   GLU n 
1 9   ARG n 
1 10  ALA n 
1 11  VAL n 
1 12  ARG n 
1 13  ASN n 
1 14  TRP n 
1 15  THR n 
1 16  ALA n 
1 17  GLY n 
1 18  ARG n 
1 19  PRO n 
1 20  HIS n 
1 21  ARG n 
1 22  PRO n 
1 23  ALA n 
1 24  PRO n 
1 25  MET n 
1 26  ARG n 
1 27  PRO n 
1 28  PRO n 
1 29  ARG n 
1 30  SER n 
1 31  GLU n 
1 32  GLU n 
1 33  THR n 
1 34  ALA n 
1 35  SER n 
1 36  GLU n 
1 37  ARG n 
1 38  PRO n 
1 39  SER n 
1 40  ARG n 
1 41  TYR n 
1 42  TYR n 
1 43  PRO n 
1 44  THR n 
1 45  TRP n 
1 46  LEU n 
1 47  PRO n 
1 48  SER n 
1 49  ARG n 
1 50  SER n 
1 51  PHE n 
1 52  ILE n 
1 53  ALA n 
1 54  ALA n 
1 55  VAL n 
1 56  ILE n 
1 57  ALA n 
1 58  ILE n 
1 59  GLY n 
1 60  GLY n 
1 61  MET n 
1 62  GLN n 
1 63  LEU n 
1 64  LEU n 
1 65  ALA n 
1 66  THR n 
1 67  MET n 
1 68  ASP n 
1 69  SER n 
1 70  THR n 
1 71  VAL n 
1 72  ALA n 
1 73  ILE n 
1 74  VAL n 
1 75  ALA n 
1 76  LEU n 
1 77  PRO n 
1 78  LYS n 
1 79  ILE n 
1 80  GLN n 
1 81  ASN n 
1 82  GLU n 
1 83  LEU n 
1 84  SER n 
1 85  LEU n 
1 86  SER n 
1 87  ASP n 
1 88  ALA n 
1 89  GLY n 
1 90  ARG n 
1 91  SER n 
1 92  TRP n 
1 93  VAL n 
1 94  ILE n 
1 95  THR n 
1 96  ALA n 
1 97  TYR n 
1 98  VAL n 
1 99  LEU n 
1 100 THR n 
1 101 PHE n 
1 102 GLY n 
1 103 GLY n 
1 104 LEU n 
1 105 MET n 
1 106 LEU n 
1 107 LEU n 
1 108 GLY n 
1 109 GLY n 
1 110 ARG n 
1 111 LEU n 
1 112 GLY n 
1 113 ASP n 
1 114 THR n 
1 115 ILE n 
1 116 GLY n 
1 117 ARG n 
1 118 LYS n 
1 119 ARG n 
1 120 THR n 
1 121 PHE n 
1 122 ILE n 
1 123 VAL n 
1 124 GLY n 
1 125 VAL n 
1 126 ALA n 
1 127 LEU n 
1 128 PHE n 
1 129 THR n 
1 130 ILE n 
1 131 SER n 
1 132 SER n 
1 133 VAL n 
1 134 LEU n 
1 135 CYS n 
1 136 ALA n 
1 137 VAL n 
1 138 ALA n 
1 139 TRP n 
1 140 ASP n 
1 141 GLU n 
1 142 ALA n 
1 143 THR n 
1 144 LEU n 
1 145 VAL n 
1 146 ILE n 
1 147 ALA n 
1 148 ARG n 
1 149 LEU n 
1 150 SER n 
1 151 GLN n 
1 152 GLY n 
1 153 VAL n 
1 154 GLY n 
1 155 SER n 
1 156 ALA n 
1 157 ILE n 
1 158 ALA n 
1 159 SER n 
1 160 PRO n 
1 161 THR n 
1 162 GLY n 
1 163 LEU n 
1 164 ALA n 
1 165 LEU n 
1 166 VAL n 
1 167 ALA n 
1 168 THR n 
1 169 THR n 
1 170 PHE n 
1 171 PRO n 
1 172 LYS n 
1 173 GLY n 
1 174 PRO n 
1 175 ALA n 
1 176 ARG n 
1 177 ASN n 
1 178 ALA n 
1 179 ALA n 
1 180 THR n 
1 181 ALA n 
1 182 VAL n 
1 183 PHE n 
1 184 ALA n 
1 185 ALA n 
1 186 MET n 
1 187 THR n 
1 188 ALA n 
1 189 ILE n 
1 190 GLY n 
1 191 SER n 
1 192 VAL n 
1 193 MET n 
1 194 GLY n 
1 195 LEU n 
1 196 VAL n 
1 197 VAL n 
1 198 GLY n 
1 199 GLY n 
1 200 ALA n 
1 201 LEU n 
1 202 THR n 
1 203 GLU n 
1 204 VAL n 
1 205 SER n 
1 206 TRP n 
1 207 ARG n 
1 208 TRP n 
1 209 ALA n 
1 210 PHE n 
1 211 LEU n 
1 212 VAL n 
1 213 ASN n 
1 214 VAL n 
1 215 PRO n 
1 216 ILE n 
1 217 GLY n 
1 218 LEU n 
1 219 VAL n 
1 220 MET n 
1 221 ILE n 
1 222 TYR n 
1 223 LEU n 
1 224 ALA n 
1 225 ARG n 
1 226 THR n 
1 227 ALA n 
1 228 LEU n 
1 229 ARG n 
1 230 GLU n 
1 231 THR n 
1 232 ASN n 
1 233 LYS n 
1 234 GLU n 
1 235 ARG n 
1 236 MET n 
1 237 LYS n 
1 238 LEU n 
1 239 ASP n 
1 240 ALA n 
1 241 THR n 
1 242 GLY n 
1 243 ALA n 
1 244 ILE n 
1 245 LEU n 
1 246 ALA n 
1 247 THR n 
1 248 LEU n 
1 249 ALA n 
1 250 CYS n 
1 251 THR n 
1 252 ALA n 
1 253 ALA n 
1 254 VAL n 
1 255 PHE n 
1 256 ALA n 
1 257 PHE n 
1 258 SER n 
1 259 ILE n 
1 260 GLY n 
1 261 PRO n 
1 262 GLU n 
1 263 LYS n 
1 264 GLY n 
1 265 TRP n 
1 266 MET n 
1 267 SER n 
1 268 GLY n 
1 269 ILE n 
1 270 THR n 
1 271 ILE n 
1 272 GLY n 
1 273 SER n 
1 274 GLY n 
1 275 LEU n 
1 276 VAL n 
1 277 ALA n 
1 278 LEU n 
1 279 ALA n 
1 280 ALA n 
1 281 ALA n 
1 282 VAL n 
1 283 ALA n 
1 284 PHE n 
1 285 VAL n 
1 286 ILE n 
1 287 VAL n 
1 288 GLU n 
1 289 ARG n 
1 290 THR n 
1 291 ALA n 
1 292 GLU n 
1 293 ASN n 
1 294 PRO n 
1 295 VAL n 
1 296 VAL n 
1 297 PRO n 
1 298 PHE n 
1 299 HIS n 
1 300 LEU n 
1 301 PHE n 
1 302 ARG n 
1 303 ASP n 
1 304 ARG n 
1 305 ASN n 
1 306 ARG n 
1 307 LEU n 
1 308 VAL n 
1 309 THR n 
1 310 PHE n 
1 311 SER n 
1 312 ALA n 
1 313 ILE n 
1 314 LEU n 
1 315 LEU n 
1 316 ALA n 
1 317 GLY n 
1 318 GLY n 
1 319 VAL n 
1 320 MET n 
1 321 PHE n 
1 322 SER n 
1 323 LEU n 
1 324 THR n 
1 325 VAL n 
1 326 CYS n 
1 327 ILE n 
1 328 GLY n 
1 329 LEU n 
1 330 TYR n 
1 331 VAL n 
1 332 GLN n 
1 333 ASP n 
1 334 ILE n 
1 335 LEU n 
1 336 GLY n 
1 337 TYR n 
1 338 SER n 
1 339 ALA n 
1 340 LEU n 
1 341 ARG n 
1 342 ALA n 
1 343 GLY n 
1 344 VAL n 
1 345 GLY n 
1 346 PHE n 
1 347 ILE n 
1 348 PRO n 
1 349 PHE n 
1 350 VAL n 
1 351 ILE n 
1 352 ALA n 
1 353 MET n 
1 354 GLY n 
1 355 ILE n 
1 356 GLY n 
1 357 LEU n 
1 358 GLY n 
1 359 VAL n 
1 360 SER n 
1 361 SER n 
1 362 GLN n 
1 363 LEU n 
1 364 VAL n 
1 365 SER n 
1 366 ARG n 
1 367 PHE n 
1 368 SER n 
1 369 PRO n 
1 370 ARG n 
1 371 VAL n 
1 372 LEU n 
1 373 THR n 
1 374 ILE n 
1 375 GLY n 
1 376 GLY n 
1 377 GLY n 
1 378 TYR n 
1 379 LEU n 
1 380 LEU n 
1 381 PHE n 
1 382 GLY n 
1 383 ALA n 
1 384 MET n 
1 385 LEU n 
1 386 TYR n 
1 387 GLY n 
1 388 SER n 
1 389 PHE n 
1 390 PHE n 
1 391 MET n 
1 392 HIS n 
1 393 ARG n 
1 394 GLY n 
1 395 VAL n 
1 396 PRO n 
1 397 TYR n 
1 398 PHE n 
1 399 PRO n 
1 400 ASN n 
1 401 LEU n 
1 402 VAL n 
1 403 MET n 
1 404 PRO n 
1 405 ILE n 
1 406 VAL n 
1 407 VAL n 
1 408 GLY n 
1 409 GLY n 
1 410 ILE n 
1 411 GLY n 
1 412 ILE n 
1 413 GLY n 
1 414 MET n 
1 415 ALA n 
1 416 VAL n 
1 417 VAL n 
1 418 PRO n 
1 419 LEU n 
1 420 THR n 
1 421 LEU n 
1 422 SER n 
1 423 ALA n 
1 424 ILE n 
1 425 ALA n 
1 426 GLY n 
1 427 VAL n 
1 428 GLY n 
1 429 PHE n 
1 430 ASP n 
1 431 GLN n 
1 432 ILE n 
1 433 GLY n 
1 434 PRO n 
1 435 VAL n 
1 436 SER n 
1 437 ALA n 
1 438 ILE n 
1 439 ALA n 
1 440 LEU n 
1 441 MET n 
1 442 LEU n 
1 443 GLN n 
1 444 SER n 
1 445 LEU n 
1 446 GLY n 
1 447 GLY n 
1 448 PRO n 
1 449 LEU n 
1 450 VAL n 
1 451 LEU n 
1 452 ALA n 
1 453 VAL n 
1 454 ILE n 
1 455 GLN n 
1 456 ALA n 
1 457 VAL n 
1 458 ILE n 
1 459 THR n 
1 460 SER n 
1 461 ARG n 
1 462 THR n 
1 463 LEU n 
1 464 TYR n 
1 465 LEU n 
1 466 GLY n 
1 467 GLY n 
1 468 THR n 
1 469 THR n 
1 470 GLY n 
1 471 PRO n 
1 472 VAL n 
1 473 LYS n 
1 474 PHE n 
1 475 MET n 
1 476 ASN n 
1 477 ASP n 
1 478 VAL n 
1 479 GLN n 
1 480 LEU n 
1 481 ALA n 
1 482 ALA n 
1 483 LEU n 
1 484 ASP n 
1 485 HIS n 
1 486 ALA n 
1 487 TYR n 
1 488 THR n 
1 489 TYR n 
1 490 GLY n 
1 491 LEU n 
1 492 LEU n 
1 493 TRP n 
1 494 VAL n 
1 495 ALA n 
1 496 GLY n 
1 497 ALA n 
1 498 ALA n 
1 499 ILE n 
1 500 ILE n 
1 501 VAL n 
1 502 GLY n 
1 503 GLY n 
1 504 MET n 
1 505 ALA n 
1 506 LEU n 
1 507 PHE n 
1 508 ILE n 
1 509 GLY n 
1 510 TYR n 
1 511 THR n 
1 512 PRO n 
1 513 GLN n 
1 514 GLN n 
1 515 VAL n 
1 516 ALA n 
1 517 HIS n 
1 518 ALA n 
1 519 GLN n 
1 520 GLU n 
1 521 VAL n 
1 522 LYS n 
1 523 GLU n 
1 524 ALA n 
1 525 ILE n 
1 526 ASP n 
1 527 ALA n 
1 528 GLY n 
1 529 GLU n 
1 530 LEU n 
1 531 ALA n 
1 532 ALA n 
1 533 ALA n 
1 534 GLU n 
1 535 ASN n 
1 536 LEU n 
1 537 TYR n 
1 538 PHE n 
1 539 GLN n 
1 540 GLY n 
1 541 LEU n 
1 542 TRP n 
1 543 SER n 
1 544 HIS n 
1 545 PRO n 
1 546 GLN n 
1 547 PHE n 
1 548 GLU n 
1 549 LYS n 
1 550 GLY n 
1 551 GLY n 
1 552 GLY n 
1 553 SER n 
1 554 GLY n 
1 555 GLY n 
1 556 GLY n 
1 557 SER n 
1 558 GLY n 
1 559 GLY n 
1 560 SER n 
1 561 ALA n 
1 562 TRP n 
1 563 SER n 
1 564 HIS n 
1 565 PRO n 
1 566 GLN n 
1 567 PHE n 
1 568 GLU n 
1 569 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   569 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 efpA 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Mycobacterium tuberculosis' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1773 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Schizosaccharomyces pombe' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     4896 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2'    117.146 
Y86 non-polymer         . 
'[(2~{R})-1-[(9~{Z},12~{Z},15~{E})-octadeca-9,12,15-trienoyl]oxy-3-phosphonooxy-propan-2-yl] nonadecanoate' ? 'C40 H73 O8 P'   
712.977 
Y8F non-polymer         . '[(2~{S})-1-dodecanoyloxy-3-phosphonooxy-propan-2-yl] tridecanoate' ? 'C28 H55 O8 P'   550.705 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   THR 2   2   ?   ?   ?   A . n 
A 1 3   ALA 3   3   ?   ?   ?   A . n 
A 1 4   LEU 4   4   ?   ?   ?   A . n 
A 1 5   ASN 5   5   ?   ?   ?   A . n 
A 1 6   ASP 6   6   ?   ?   ?   A . n 
A 1 7   THR 7   7   ?   ?   ?   A . n 
A 1 8   GLU 8   8   ?   ?   ?   A . n 
A 1 9   ARG 9   9   ?   ?   ?   A . n 
A 1 10  ALA 10  10  ?   ?   ?   A . n 
A 1 11  VAL 11  11  ?   ?   ?   A . n 
A 1 12  ARG 12  12  ?   ?   ?   A . n 
A 1 13  ASN 13  13  ?   ?   ?   A . n 
A 1 14  TRP 14  14  ?   ?   ?   A . n 
A 1 15  THR 15  15  ?   ?   ?   A . n 
A 1 16  ALA 16  16  ?   ?   ?   A . n 
A 1 17  GLY 17  17  ?   ?   ?   A . n 
A 1 18  ARG 18  18  ?   ?   ?   A . n 
A 1 19  PRO 19  19  ?   ?   ?   A . n 
A 1 20  HIS 20  20  ?   ?   ?   A . n 
A 1 21  ARG 21  21  ?   ?   ?   A . n 
A 1 22  PRO 22  22  ?   ?   ?   A . n 
A 1 23  ALA 23  23  ?   ?   ?   A . n 
A 1 24  PRO 24  24  ?   ?   ?   A . n 
A 1 25  MET 25  25  ?   ?   ?   A . n 
A 1 26  ARG 26  26  ?   ?   ?   A . n 
A 1 27  PRO 27  27  ?   ?   ?   A . n 
A 1 28  PRO 28  28  ?   ?   ?   A . n 
A 1 29  ARG 29  29  ?   ?   ?   A . n 
A 1 30  SER 30  30  ?   ?   ?   A . n 
A 1 31  GLU 31  31  ?   ?   ?   A . n 
A 1 32  GLU 32  32  ?   ?   ?   A . n 
A 1 33  THR 33  33  ?   ?   ?   A . n 
A 1 34  ALA 34  34  ?   ?   ?   A . n 
A 1 35  SER 35  35  ?   ?   ?   A . n 
A 1 36  GLU 36  36  ?   ?   ?   A . n 
A 1 37  ARG 37  37  ?   ?   ?   A . n 
A 1 38  PRO 38  38  ?   ?   ?   A . n 
A 1 39  SER 39  39  ?   ?   ?   A . n 
A 1 40  ARG 40  40  ?   ?   ?   A . n 
A 1 41  TYR 41  41  ?   ?   ?   A . n 
A 1 42  TYR 42  42  ?   ?   ?   A . n 
A 1 43  PRO 43  43  ?   ?   ?   A . n 
A 1 44  THR 44  44  ?   ?   ?   A . n 
A 1 45  TRP 45  45  ?   ?   ?   A . n 
A 1 46  LEU 46  46  ?   ?   ?   A . n 
A 1 47  PRO 47  47  ?   ?   ?   A . n 
A 1 48  SER 48  48  48  SER SER A . n 
A 1 49  ARG 49  49  49  ARG ARG A . n 
A 1 50  SER 50  50  50  SER SER A . n 
A 1 51  PHE 51  51  51  PHE PHE A . n 
A 1 52  ILE 52  52  52  ILE ILE A . n 
A 1 53  ALA 53  53  53  ALA ALA A . n 
A 1 54  ALA 54  54  54  ALA ALA A . n 
A 1 55  VAL 55  55  55  VAL VAL A . n 
A 1 56  ILE 56  56  56  ILE ILE A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  ILE 58  58  58  ILE ILE A . n 
A 1 59  GLY 59  59  59  GLY GLY A . n 
A 1 60  GLY 60  60  60  GLY GLY A . n 
A 1 61  MET 61  61  61  MET MET A . n 
A 1 62  GLN 62  62  62  GLN GLN A . n 
A 1 63  LEU 63  63  63  LEU LEU A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  ALA 65  65  65  ALA ALA A . n 
A 1 66  THR 66  66  66  THR THR A . n 
A 1 67  MET 67  67  67  MET MET A . n 
A 1 68  ASP 68  68  68  ASP ASP A . n 
A 1 69  SER 69  69  69  SER SER A . n 
A 1 70  THR 70  70  70  THR THR A . n 
A 1 71  VAL 71  71  71  VAL VAL A . n 
A 1 72  ALA 72  72  72  ALA ALA A . n 
A 1 73  ILE 73  73  73  ILE ILE A . n 
A 1 74  VAL 74  74  74  VAL VAL A . n 
A 1 75  ALA 75  75  75  ALA ALA A . n 
A 1 76  LEU 76  76  76  LEU LEU A . n 
A 1 77  PRO 77  77  77  PRO PRO A . n 
A 1 78  LYS 78  78  78  LYS LYS A . n 
A 1 79  ILE 79  79  79  ILE ILE A . n 
A 1 80  GLN 80  80  80  GLN GLN A . n 
A 1 81  ASN 81  81  81  ASN ASN A . n 
A 1 82  GLU 82  82  82  GLU GLU A . n 
A 1 83  LEU 83  83  83  LEU LEU A . n 
A 1 84  SER 84  84  84  SER SER A . n 
A 1 85  LEU 85  85  85  LEU LEU A . n 
A 1 86  SER 86  86  86  SER SER A . n 
A 1 87  ASP 87  87  87  ASP ASP A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  GLY 89  89  89  GLY GLY A . n 
A 1 90  ARG 90  90  90  ARG ARG A . n 
A 1 91  SER 91  91  91  SER SER A . n 
A 1 92  TRP 92  92  92  TRP TRP A . n 
A 1 93  VAL 93  93  93  VAL VAL A . n 
A 1 94  ILE 94  94  94  ILE ILE A . n 
A 1 95  THR 95  95  95  THR THR A . n 
A 1 96  ALA 96  96  96  ALA ALA A . n 
A 1 97  TYR 97  97  97  TYR TYR A . n 
A 1 98  VAL 98  98  98  VAL VAL A . n 
A 1 99  LEU 99  99  99  LEU LEU A . n 
A 1 100 THR 100 100 100 THR THR A . n 
A 1 101 PHE 101 101 101 PHE PHE A . n 
A 1 102 GLY 102 102 102 GLY GLY A . n 
A 1 103 GLY 103 103 103 GLY GLY A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 MET 105 105 105 MET MET A . n 
A 1 106 LEU 106 106 106 LEU LEU A . n 
A 1 107 LEU 107 107 107 LEU LEU A . n 
A 1 108 GLY 108 108 108 GLY GLY A . n 
A 1 109 GLY 109 109 109 GLY GLY A . n 
A 1 110 ARG 110 110 110 ARG ARG A . n 
A 1 111 LEU 111 111 111 LEU LEU A . n 
A 1 112 GLY 112 112 112 GLY GLY A . n 
A 1 113 ASP 113 113 113 ASP ASP A . n 
A 1 114 THR 114 114 114 THR THR A . n 
A 1 115 ILE 115 115 115 ILE ILE A . n 
A 1 116 GLY 116 116 116 GLY GLY A . n 
A 1 117 ARG 117 117 117 ARG ARG A . n 
A 1 118 LYS 118 118 118 LYS LYS A . n 
A 1 119 ARG 119 119 119 ARG ARG A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 PHE 121 121 121 PHE PHE A . n 
A 1 122 ILE 122 122 122 ILE ILE A . n 
A 1 123 VAL 123 123 123 VAL VAL A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 ALA 126 126 126 ALA ALA A . n 
A 1 127 LEU 127 127 127 LEU LEU A . n 
A 1 128 PHE 128 128 128 PHE PHE A . n 
A 1 129 THR 129 129 129 THR THR A . n 
A 1 130 ILE 130 130 130 ILE ILE A . n 
A 1 131 SER 131 131 131 SER SER A . n 
A 1 132 SER 132 132 132 SER SER A . n 
A 1 133 VAL 133 133 133 VAL VAL A . n 
A 1 134 LEU 134 134 134 LEU LEU A . n 
A 1 135 CYS 135 135 135 CYS CYS A . n 
A 1 136 ALA 136 136 136 ALA ALA A . n 
A 1 137 VAL 137 137 137 VAL VAL A . n 
A 1 138 ALA 138 138 138 ALA ALA A . n 
A 1 139 TRP 139 139 139 TRP TRP A . n 
A 1 140 ASP 140 140 140 ASP ASP A . n 
A 1 141 GLU 141 141 141 GLU GLU A . n 
A 1 142 ALA 142 142 142 ALA ALA A . n 
A 1 143 THR 143 143 143 THR THR A . n 
A 1 144 LEU 144 144 144 LEU LEU A . n 
A 1 145 VAL 145 145 145 VAL VAL A . n 
A 1 146 ILE 146 146 146 ILE ILE A . n 
A 1 147 ALA 147 147 147 ALA ALA A . n 
A 1 148 ARG 148 148 148 ARG ARG A . n 
A 1 149 LEU 149 149 149 LEU LEU A . n 
A 1 150 SER 150 150 150 SER SER A . n 
A 1 151 GLN 151 151 151 GLN GLN A . n 
A 1 152 GLY 152 152 152 GLY GLY A . n 
A 1 153 VAL 153 153 153 VAL VAL A . n 
A 1 154 GLY 154 154 154 GLY GLY A . n 
A 1 155 SER 155 155 155 SER SER A . n 
A 1 156 ALA 156 156 156 ALA ALA A . n 
A 1 157 ILE 157 157 157 ILE ILE A . n 
A 1 158 ALA 158 158 158 ALA ALA A . n 
A 1 159 SER 159 159 159 SER SER A . n 
A 1 160 PRO 160 160 160 PRO PRO A . n 
A 1 161 THR 161 161 161 THR THR A . n 
A 1 162 GLY 162 162 162 GLY GLY A . n 
A 1 163 LEU 163 163 163 LEU LEU A . n 
A 1 164 ALA 164 164 164 ALA ALA A . n 
A 1 165 LEU 165 165 165 LEU LEU A . n 
A 1 166 VAL 166 166 166 VAL VAL A . n 
A 1 167 ALA 167 167 167 ALA ALA A . n 
A 1 168 THR 168 168 168 THR THR A . n 
A 1 169 THR 169 169 169 THR THR A . n 
A 1 170 PHE 170 170 170 PHE PHE A . n 
A 1 171 PRO 171 171 171 PRO PRO A . n 
A 1 172 LYS 172 172 172 LYS LYS A . n 
A 1 173 GLY 173 173 173 GLY GLY A . n 
A 1 174 PRO 174 174 174 PRO PRO A . n 
A 1 175 ALA 175 175 175 ALA ALA A . n 
A 1 176 ARG 176 176 176 ARG ARG A . n 
A 1 177 ASN 177 177 177 ASN ASN A . n 
A 1 178 ALA 178 178 178 ALA ALA A . n 
A 1 179 ALA 179 179 179 ALA ALA A . n 
A 1 180 THR 180 180 180 THR THR A . n 
A 1 181 ALA 181 181 181 ALA ALA A . n 
A 1 182 VAL 182 182 182 VAL VAL A . n 
A 1 183 PHE 183 183 183 PHE PHE A . n 
A 1 184 ALA 184 184 184 ALA ALA A . n 
A 1 185 ALA 185 185 185 ALA ALA A . n 
A 1 186 MET 186 186 186 MET MET A . n 
A 1 187 THR 187 187 187 THR THR A . n 
A 1 188 ALA 188 188 188 ALA ALA A . n 
A 1 189 ILE 189 189 189 ILE ILE A . n 
A 1 190 GLY 190 190 190 GLY GLY A . n 
A 1 191 SER 191 191 191 SER SER A . n 
A 1 192 VAL 192 192 192 VAL VAL A . n 
A 1 193 MET 193 193 193 MET MET A . n 
A 1 194 GLY 194 194 194 GLY GLY A . n 
A 1 195 LEU 195 195 195 LEU LEU A . n 
A 1 196 VAL 196 196 196 VAL VAL A . n 
A 1 197 VAL 197 197 197 VAL VAL A . n 
A 1 198 GLY 198 198 198 GLY GLY A . n 
A 1 199 GLY 199 199 199 GLY GLY A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 LEU 201 201 201 LEU LEU A . n 
A 1 202 THR 202 202 202 THR THR A . n 
A 1 203 GLU 203 203 203 GLU GLU A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 SER 205 205 205 SER SER A . n 
A 1 206 TRP 206 206 206 TRP TRP A . n 
A 1 207 ARG 207 207 207 ARG ARG A . n 
A 1 208 TRP 208 208 208 TRP TRP A . n 
A 1 209 ALA 209 209 209 ALA ALA A . n 
A 1 210 PHE 210 210 210 PHE PHE A . n 
A 1 211 LEU 211 211 211 LEU LEU A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 ASN 213 213 213 ASN ASN A . n 
A 1 214 VAL 214 214 214 VAL VAL A . n 
A 1 215 PRO 215 215 215 PRO PRO A . n 
A 1 216 ILE 216 216 216 ILE ILE A . n 
A 1 217 GLY 217 217 217 GLY GLY A . n 
A 1 218 LEU 218 218 218 LEU LEU A . n 
A 1 219 VAL 219 219 219 VAL VAL A . n 
A 1 220 MET 220 220 220 MET MET A . n 
A 1 221 ILE 221 221 221 ILE ILE A . n 
A 1 222 TYR 222 222 222 TYR TYR A . n 
A 1 223 LEU 223 223 223 LEU LEU A . n 
A 1 224 ALA 224 224 224 ALA ALA A . n 
A 1 225 ARG 225 225 225 ARG ARG A . n 
A 1 226 THR 226 226 226 THR THR A . n 
A 1 227 ALA 227 227 227 ALA ALA A . n 
A 1 228 LEU 228 228 228 LEU LEU A . n 
A 1 229 ARG 229 229 229 ARG ARG A . n 
A 1 230 GLU 230 230 230 GLU GLU A . n 
A 1 231 THR 231 231 231 THR THR A . n 
A 1 232 ASN 232 232 232 ASN ASN A . n 
A 1 233 LYS 233 233 233 LYS LYS A . n 
A 1 234 GLU 234 234 234 GLU GLU A . n 
A 1 235 ARG 235 235 235 ARG ARG A . n 
A 1 236 MET 236 236 236 MET MET A . n 
A 1 237 LYS 237 237 237 LYS LYS A . n 
A 1 238 LEU 238 238 238 LEU LEU A . n 
A 1 239 ASP 239 239 239 ASP ASP A . n 
A 1 240 ALA 240 240 240 ALA ALA A . n 
A 1 241 THR 241 241 241 THR THR A . n 
A 1 242 GLY 242 242 242 GLY GLY A . n 
A 1 243 ALA 243 243 243 ALA ALA A . n 
A 1 244 ILE 244 244 244 ILE ILE A . n 
A 1 245 LEU 245 245 245 LEU LEU A . n 
A 1 246 ALA 246 246 246 ALA ALA A . n 
A 1 247 THR 247 247 247 THR THR A . n 
A 1 248 LEU 248 248 248 LEU LEU A . n 
A 1 249 ALA 249 249 249 ALA ALA A . n 
A 1 250 CYS 250 250 250 CYS CYS A . n 
A 1 251 THR 251 251 251 THR THR A . n 
A 1 252 ALA 252 252 252 ALA ALA A . n 
A 1 253 ALA 253 253 253 ALA ALA A . n 
A 1 254 VAL 254 254 254 VAL VAL A . n 
A 1 255 PHE 255 255 255 PHE PHE A . n 
A 1 256 ALA 256 256 256 ALA ALA A . n 
A 1 257 PHE 257 257 257 PHE PHE A . n 
A 1 258 SER 258 258 258 SER SER A . n 
A 1 259 ILE 259 259 259 ILE ILE A . n 
A 1 260 GLY 260 260 260 GLY GLY A . n 
A 1 261 PRO 261 261 261 PRO PRO A . n 
A 1 262 GLU 262 262 262 GLU GLU A . n 
A 1 263 LYS 263 263 263 LYS LYS A . n 
A 1 264 GLY 264 264 264 GLY GLY A . n 
A 1 265 TRP 265 265 265 TRP TRP A . n 
A 1 266 MET 266 266 266 MET MET A . n 
A 1 267 SER 267 267 267 SER SER A . n 
A 1 268 GLY 268 268 268 GLY GLY A . n 
A 1 269 ILE 269 269 269 ILE ILE A . n 
A 1 270 THR 270 270 270 THR THR A . n 
A 1 271 ILE 271 271 271 ILE ILE A . n 
A 1 272 GLY 272 272 272 GLY GLY A . n 
A 1 273 SER 273 273 273 SER SER A . n 
A 1 274 GLY 274 274 274 GLY GLY A . n 
A 1 275 LEU 275 275 275 LEU LEU A . n 
A 1 276 VAL 276 276 276 VAL VAL A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 LEU 278 278 278 LEU LEU A . n 
A 1 279 ALA 279 279 279 ALA ALA A . n 
A 1 280 ALA 280 280 280 ALA ALA A . n 
A 1 281 ALA 281 281 281 ALA ALA A . n 
A 1 282 VAL 282 282 282 VAL VAL A . n 
A 1 283 ALA 283 283 283 ALA ALA A . n 
A 1 284 PHE 284 284 284 PHE PHE A . n 
A 1 285 VAL 285 285 285 VAL VAL A . n 
A 1 286 ILE 286 286 286 ILE ILE A . n 
A 1 287 VAL 287 287 287 VAL VAL A . n 
A 1 288 GLU 288 288 288 GLU GLU A . n 
A 1 289 ARG 289 289 289 ARG ARG A . n 
A 1 290 THR 290 290 290 THR THR A . n 
A 1 291 ALA 291 291 291 ALA ALA A . n 
A 1 292 GLU 292 292 292 GLU GLU A . n 
A 1 293 ASN 293 293 293 ASN ASN A . n 
A 1 294 PRO 294 294 294 PRO PRO A . n 
A 1 295 VAL 295 295 295 VAL VAL A . n 
A 1 296 VAL 296 296 296 VAL VAL A . n 
A 1 297 PRO 297 297 297 PRO PRO A . n 
A 1 298 PHE 298 298 298 PHE PHE A . n 
A 1 299 HIS 299 299 299 HIS HIS A . n 
A 1 300 LEU 300 300 300 LEU LEU A . n 
A 1 301 PHE 301 301 301 PHE PHE A . n 
A 1 302 ARG 302 302 302 ARG ARG A . n 
A 1 303 ASP 303 303 303 ASP ASP A . n 
A 1 304 ARG 304 304 304 ARG ARG A . n 
A 1 305 ASN 305 305 305 ASN ASN A . n 
A 1 306 ARG 306 306 306 ARG ARG A . n 
A 1 307 LEU 307 307 307 LEU LEU A . n 
A 1 308 VAL 308 308 308 VAL VAL A . n 
A 1 309 THR 309 309 309 THR THR A . n 
A 1 310 PHE 310 310 310 PHE PHE A . n 
A 1 311 SER 311 311 311 SER SER A . n 
A 1 312 ALA 312 312 312 ALA ALA A . n 
A 1 313 ILE 313 313 313 ILE ILE A . n 
A 1 314 LEU 314 314 314 LEU LEU A . n 
A 1 315 LEU 315 315 315 LEU LEU A . n 
A 1 316 ALA 316 316 316 ALA ALA A . n 
A 1 317 GLY 317 317 317 GLY GLY A . n 
A 1 318 GLY 318 318 318 GLY GLY A . n 
A 1 319 VAL 319 319 319 VAL VAL A . n 
A 1 320 MET 320 320 320 MET MET A . n 
A 1 321 PHE 321 321 321 PHE PHE A . n 
A 1 322 SER 322 322 322 SER SER A . n 
A 1 323 LEU 323 323 323 LEU LEU A . n 
A 1 324 THR 324 324 324 THR THR A . n 
A 1 325 VAL 325 325 325 VAL VAL A . n 
A 1 326 CYS 326 326 326 CYS CYS A . n 
A 1 327 ILE 327 327 327 ILE ILE A . n 
A 1 328 GLY 328 328 328 GLY GLY A . n 
A 1 329 LEU 329 329 329 LEU LEU A . n 
A 1 330 TYR 330 330 330 TYR TYR A . n 
A 1 331 VAL 331 331 331 VAL VAL A . n 
A 1 332 GLN 332 332 332 GLN GLN A . n 
A 1 333 ASP 333 333 333 ASP ASP A . n 
A 1 334 ILE 334 334 334 ILE ILE A . n 
A 1 335 LEU 335 335 335 LEU LEU A . n 
A 1 336 GLY 336 336 336 GLY GLY A . n 
A 1 337 TYR 337 337 337 TYR TYR A . n 
A 1 338 SER 338 338 338 SER SER A . n 
A 1 339 ALA 339 339 339 ALA ALA A . n 
A 1 340 LEU 340 340 340 LEU LEU A . n 
A 1 341 ARG 341 341 341 ARG ARG A . n 
A 1 342 ALA 342 342 342 ALA ALA A . n 
A 1 343 GLY 343 343 343 GLY GLY A . n 
A 1 344 VAL 344 344 344 VAL VAL A . n 
A 1 345 GLY 345 345 345 GLY GLY A . n 
A 1 346 PHE 346 346 346 PHE PHE A . n 
A 1 347 ILE 347 347 347 ILE ILE A . n 
A 1 348 PRO 348 348 348 PRO PRO A . n 
A 1 349 PHE 349 349 349 PHE PHE A . n 
A 1 350 VAL 350 350 350 VAL VAL A . n 
A 1 351 ILE 351 351 351 ILE ILE A . n 
A 1 352 ALA 352 352 352 ALA ALA A . n 
A 1 353 MET 353 353 353 MET MET A . n 
A 1 354 GLY 354 354 354 GLY GLY A . n 
A 1 355 ILE 355 355 355 ILE ILE A . n 
A 1 356 GLY 356 356 356 GLY GLY A . n 
A 1 357 LEU 357 357 357 LEU LEU A . n 
A 1 358 GLY 358 358 358 GLY GLY A . n 
A 1 359 VAL 359 359 359 VAL VAL A . n 
A 1 360 SER 360 360 360 SER SER A . n 
A 1 361 SER 361 361 361 SER SER A . n 
A 1 362 GLN 362 362 362 GLN GLN A . n 
A 1 363 LEU 363 363 363 LEU LEU A . n 
A 1 364 VAL 364 364 364 VAL VAL A . n 
A 1 365 SER 365 365 365 SER SER A . n 
A 1 366 ARG 366 366 366 ARG ARG A . n 
A 1 367 PHE 367 367 367 PHE PHE A . n 
A 1 368 SER 368 368 368 SER SER A . n 
A 1 369 PRO 369 369 369 PRO PRO A . n 
A 1 370 ARG 370 370 370 ARG ARG A . n 
A 1 371 VAL 371 371 371 VAL VAL A . n 
A 1 372 LEU 372 372 372 LEU LEU A . n 
A 1 373 THR 373 373 373 THR THR A . n 
A 1 374 ILE 374 374 374 ILE ILE A . n 
A 1 375 GLY 375 375 375 GLY GLY A . n 
A 1 376 GLY 376 376 376 GLY GLY A . n 
A 1 377 GLY 377 377 377 GLY GLY A . n 
A 1 378 TYR 378 378 378 TYR TYR A . n 
A 1 379 LEU 379 379 379 LEU LEU A . n 
A 1 380 LEU 380 380 380 LEU LEU A . n 
A 1 381 PHE 381 381 381 PHE PHE A . n 
A 1 382 GLY 382 382 382 GLY GLY A . n 
A 1 383 ALA 383 383 383 ALA ALA A . n 
A 1 384 MET 384 384 384 MET MET A . n 
A 1 385 LEU 385 385 385 LEU LEU A . n 
A 1 386 TYR 386 386 386 TYR TYR A . n 
A 1 387 GLY 387 387 387 GLY GLY A . n 
A 1 388 SER 388 388 388 SER SER A . n 
A 1 389 PHE 389 389 389 PHE PHE A . n 
A 1 390 PHE 390 390 390 PHE PHE A . n 
A 1 391 MET 391 391 391 MET MET A . n 
A 1 392 HIS 392 392 392 HIS HIS A . n 
A 1 393 ARG 393 393 393 ARG ARG A . n 
A 1 394 GLY 394 394 394 GLY GLY A . n 
A 1 395 VAL 395 395 395 VAL VAL A . n 
A 1 396 PRO 396 396 396 PRO PRO A . n 
A 1 397 TYR 397 397 397 TYR TYR A . n 
A 1 398 PHE 398 398 398 PHE PHE A . n 
A 1 399 PRO 399 399 399 PRO PRO A . n 
A 1 400 ASN 400 400 400 ASN ASN A . n 
A 1 401 LEU 401 401 401 LEU LEU A . n 
A 1 402 VAL 402 402 402 VAL VAL A . n 
A 1 403 MET 403 403 403 MET MET A . n 
A 1 404 PRO 404 404 404 PRO PRO A . n 
A 1 405 ILE 405 405 405 ILE ILE A . n 
A 1 406 VAL 406 406 406 VAL VAL A . n 
A 1 407 VAL 407 407 407 VAL VAL A . n 
A 1 408 GLY 408 408 408 GLY GLY A . n 
A 1 409 GLY 409 409 409 GLY GLY A . n 
A 1 410 ILE 410 410 410 ILE ILE A . n 
A 1 411 GLY 411 411 411 GLY GLY A . n 
A 1 412 ILE 412 412 412 ILE ILE A . n 
A 1 413 GLY 413 413 413 GLY GLY A . n 
A 1 414 MET 414 414 414 MET MET A . n 
A 1 415 ALA 415 415 415 ALA ALA A . n 
A 1 416 VAL 416 416 416 VAL VAL A . n 
A 1 417 VAL 417 417 417 VAL VAL A . n 
A 1 418 PRO 418 418 418 PRO PRO A . n 
A 1 419 LEU 419 419 419 LEU LEU A . n 
A 1 420 THR 420 420 420 THR THR A . n 
A 1 421 LEU 421 421 421 LEU LEU A . n 
A 1 422 SER 422 422 422 SER SER A . n 
A 1 423 ALA 423 423 423 ALA ALA A . n 
A 1 424 ILE 424 424 424 ILE ILE A . n 
A 1 425 ALA 425 425 425 ALA ALA A . n 
A 1 426 GLY 426 426 426 GLY GLY A . n 
A 1 427 VAL 427 427 427 VAL VAL A . n 
A 1 428 GLY 428 428 428 GLY GLY A . n 
A 1 429 PHE 429 429 429 PHE PHE A . n 
A 1 430 ASP 430 430 430 ASP ASP A . n 
A 1 431 GLN 431 431 431 GLN GLN A . n 
A 1 432 ILE 432 432 432 ILE ILE A . n 
A 1 433 GLY 433 433 433 GLY GLY A . n 
A 1 434 PRO 434 434 434 PRO PRO A . n 
A 1 435 VAL 435 435 435 VAL VAL A . n 
A 1 436 SER 436 436 436 SER SER A . n 
A 1 437 ALA 437 437 437 ALA ALA A . n 
A 1 438 ILE 438 438 438 ILE ILE A . n 
A 1 439 ALA 439 439 439 ALA ALA A . n 
A 1 440 LEU 440 440 440 LEU LEU A . n 
A 1 441 MET 441 441 441 MET MET A . n 
A 1 442 LEU 442 442 442 LEU LEU A . n 
A 1 443 GLN 443 443 443 GLN GLN A . n 
A 1 444 SER 444 444 444 SER SER A . n 
A 1 445 LEU 445 445 445 LEU LEU A . n 
A 1 446 GLY 446 446 446 GLY GLY A . n 
A 1 447 GLY 447 447 447 GLY GLY A . n 
A 1 448 PRO 448 448 448 PRO PRO A . n 
A 1 449 LEU 449 449 449 LEU LEU A . n 
A 1 450 VAL 450 450 450 VAL VAL A . n 
A 1 451 LEU 451 451 451 LEU LEU A . n 
A 1 452 ALA 452 452 452 ALA ALA A . n 
A 1 453 VAL 453 453 453 VAL VAL A . n 
A 1 454 ILE 454 454 454 ILE ILE A . n 
A 1 455 GLN 455 455 455 GLN GLN A . n 
A 1 456 ALA 456 456 456 ALA ALA A . n 
A 1 457 VAL 457 457 457 VAL VAL A . n 
A 1 458 ILE 458 458 458 ILE ILE A . n 
A 1 459 THR 459 459 459 THR THR A . n 
A 1 460 SER 460 460 460 SER SER A . n 
A 1 461 ARG 461 461 461 ARG ARG A . n 
A 1 462 THR 462 462 462 THR THR A . n 
A 1 463 LEU 463 463 463 LEU LEU A . n 
A 1 464 TYR 464 464 464 TYR TYR A . n 
A 1 465 LEU 465 465 465 LEU LEU A . n 
A 1 466 GLY 466 466 466 GLY GLY A . n 
A 1 467 GLY 467 467 467 GLY GLY A . n 
A 1 468 THR 468 468 468 THR THR A . n 
A 1 469 THR 469 469 469 THR THR A . n 
A 1 470 GLY 470 470 470 GLY GLY A . n 
A 1 471 PRO 471 471 471 PRO PRO A . n 
A 1 472 VAL 472 472 472 VAL VAL A . n 
A 1 473 LYS 473 473 473 LYS LYS A . n 
A 1 474 PHE 474 474 474 PHE PHE A . n 
A 1 475 MET 475 475 475 MET MET A . n 
A 1 476 ASN 476 476 476 ASN ASN A . n 
A 1 477 ASP 477 477 477 ASP ASP A . n 
A 1 478 VAL 478 478 478 VAL VAL A . n 
A 1 479 GLN 479 479 479 GLN GLN A . n 
A 1 480 LEU 480 480 480 LEU LEU A . n 
A 1 481 ALA 481 481 481 ALA ALA A . n 
A 1 482 ALA 482 482 482 ALA ALA A . n 
A 1 483 LEU 483 483 483 LEU LEU A . n 
A 1 484 ASP 484 484 484 ASP ASP A . n 
A 1 485 HIS 485 485 485 HIS HIS A . n 
A 1 486 ALA 486 486 486 ALA ALA A . n 
A 1 487 TYR 487 487 487 TYR TYR A . n 
A 1 488 THR 488 488 488 THR THR A . n 
A 1 489 TYR 489 489 489 TYR TYR A . n 
A 1 490 GLY 490 490 490 GLY GLY A . n 
A 1 491 LEU 491 491 491 LEU LEU A . n 
A 1 492 LEU 492 492 492 LEU LEU A . n 
A 1 493 TRP 493 493 493 TRP TRP A . n 
A 1 494 VAL 494 494 494 VAL VAL A . n 
A 1 495 ALA 495 495 495 ALA ALA A . n 
A 1 496 GLY 496 496 496 GLY GLY A . n 
A 1 497 ALA 497 497 497 ALA ALA A . n 
A 1 498 ALA 498 498 498 ALA ALA A . n 
A 1 499 ILE 499 499 499 ILE ILE A . n 
A 1 500 ILE 500 500 500 ILE ILE A . n 
A 1 501 VAL 501 501 501 VAL VAL A . n 
A 1 502 GLY 502 502 502 GLY GLY A . n 
A 1 503 GLY 503 503 503 GLY GLY A . n 
A 1 504 MET 504 504 504 MET MET A . n 
A 1 505 ALA 505 505 505 ALA ALA A . n 
A 1 506 LEU 506 506 506 LEU LEU A . n 
A 1 507 PHE 507 507 507 PHE PHE A . n 
A 1 508 ILE 508 508 508 ILE ILE A . n 
A 1 509 GLY 509 509 509 GLY GLY A . n 
A 1 510 TYR 510 510 510 TYR TYR A . n 
A 1 511 THR 511 511 511 THR THR A . n 
A 1 512 PRO 512 512 512 PRO PRO A . n 
A 1 513 GLN 513 513 513 GLN GLN A . n 
A 1 514 GLN 514 514 514 GLN GLN A . n 
A 1 515 VAL 515 515 515 VAL VAL A . n 
A 1 516 ALA 516 516 516 ALA ALA A . n 
A 1 517 HIS 517 517 517 HIS HIS A . n 
A 1 518 ALA 518 518 518 ALA ALA A . n 
A 1 519 GLN 519 519 519 GLN GLN A . n 
A 1 520 GLU 520 520 ?   ?   ?   A . n 
A 1 521 VAL 521 521 ?   ?   ?   A . n 
A 1 522 LYS 522 522 ?   ?   ?   A . n 
A 1 523 GLU 523 523 ?   ?   ?   A . n 
A 1 524 ALA 524 524 ?   ?   ?   A . n 
A 1 525 ILE 525 525 ?   ?   ?   A . n 
A 1 526 ASP 526 526 ?   ?   ?   A . n 
A 1 527 ALA 527 527 ?   ?   ?   A . n 
A 1 528 GLY 528 528 ?   ?   ?   A . n 
A 1 529 GLU 529 529 ?   ?   ?   A . n 
A 1 530 LEU 530 530 ?   ?   ?   A . n 
A 1 531 ALA 531 531 ?   ?   ?   A . n 
A 1 532 ALA 532 532 ?   ?   ?   A . n 
A 1 533 ALA 533 533 ?   ?   ?   A . n 
A 1 534 GLU 534 534 ?   ?   ?   A . n 
A 1 535 ASN 535 535 ?   ?   ?   A . n 
A 1 536 LEU 536 536 ?   ?   ?   A . n 
A 1 537 TYR 537 537 ?   ?   ?   A . n 
A 1 538 PHE 538 538 ?   ?   ?   A . n 
A 1 539 GLN 539 539 ?   ?   ?   A . n 
A 1 540 GLY 540 540 ?   ?   ?   A . n 
A 1 541 LEU 541 541 ?   ?   ?   A . n 
A 1 542 TRP 542 542 ?   ?   ?   A . n 
A 1 543 SER 543 543 ?   ?   ?   A . n 
A 1 544 HIS 544 544 ?   ?   ?   A . n 
A 1 545 PRO 545 545 ?   ?   ?   A . n 
A 1 546 GLN 546 546 ?   ?   ?   A . n 
A 1 547 PHE 547 547 ?   ?   ?   A . n 
A 1 548 GLU 548 548 ?   ?   ?   A . n 
A 1 549 LYS 549 549 ?   ?   ?   A . n 
A 1 550 GLY 550 550 ?   ?   ?   A . n 
A 1 551 GLY 551 551 ?   ?   ?   A . n 
A 1 552 GLY 552 552 ?   ?   ?   A . n 
A 1 553 SER 553 553 ?   ?   ?   A . n 
A 1 554 GLY 554 554 ?   ?   ?   A . n 
A 1 555 GLY 555 555 ?   ?   ?   A . n 
A 1 556 GLY 556 556 ?   ?   ?   A . n 
A 1 557 SER 557 557 ?   ?   ?   A . n 
A 1 558 GLY 558 558 ?   ?   ?   A . n 
A 1 559 GLY 559 559 ?   ?   ?   A . n 
A 1 560 SER 560 560 ?   ?   ?   A . n 
A 1 561 ALA 561 561 ?   ?   ?   A . n 
A 1 562 TRP 562 562 ?   ?   ?   A . n 
A 1 563 SER 563 563 ?   ?   ?   A . n 
A 1 564 HIS 564 564 ?   ?   ?   A . n 
A 1 565 PRO 565 565 ?   ?   ?   A . n 
A 1 566 GLN 566 566 ?   ?   ?   A . n 
A 1 567 PHE 567 567 ?   ?   ?   A . n 
A 1 568 GLU 568 568 ?   ?   ?   A . n 
A 1 569 LYS 569 569 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   THR 2   2   ?   ?   ?   B . n 
B 1 3   ALA 3   3   ?   ?   ?   B . n 
B 1 4   LEU 4   4   ?   ?   ?   B . n 
B 1 5   ASN 5   5   ?   ?   ?   B . n 
B 1 6   ASP 6   6   ?   ?   ?   B . n 
B 1 7   THR 7   7   ?   ?   ?   B . n 
B 1 8   GLU 8   8   ?   ?   ?   B . n 
B 1 9   ARG 9   9   ?   ?   ?   B . n 
B 1 10  ALA 10  10  ?   ?   ?   B . n 
B 1 11  VAL 11  11  ?   ?   ?   B . n 
B 1 12  ARG 12  12  ?   ?   ?   B . n 
B 1 13  ASN 13  13  ?   ?   ?   B . n 
B 1 14  TRP 14  14  ?   ?   ?   B . n 
B 1 15  THR 15  15  ?   ?   ?   B . n 
B 1 16  ALA 16  16  ?   ?   ?   B . n 
B 1 17  GLY 17  17  ?   ?   ?   B . n 
B 1 18  ARG 18  18  ?   ?   ?   B . n 
B 1 19  PRO 19  19  ?   ?   ?   B . n 
B 1 20  HIS 20  20  ?   ?   ?   B . n 
B 1 21  ARG 21  21  ?   ?   ?   B . n 
B 1 22  PRO 22  22  ?   ?   ?   B . n 
B 1 23  ALA 23  23  ?   ?   ?   B . n 
B 1 24  PRO 24  24  ?   ?   ?   B . n 
B 1 25  MET 25  25  ?   ?   ?   B . n 
B 1 26  ARG 26  26  ?   ?   ?   B . n 
B 1 27  PRO 27  27  ?   ?   ?   B . n 
B 1 28  PRO 28  28  ?   ?   ?   B . n 
B 1 29  ARG 29  29  ?   ?   ?   B . n 
B 1 30  SER 30  30  ?   ?   ?   B . n 
B 1 31  GLU 31  31  ?   ?   ?   B . n 
B 1 32  GLU 32  32  ?   ?   ?   B . n 
B 1 33  THR 33  33  ?   ?   ?   B . n 
B 1 34  ALA 34  34  ?   ?   ?   B . n 
B 1 35  SER 35  35  ?   ?   ?   B . n 
B 1 36  GLU 36  36  ?   ?   ?   B . n 
B 1 37  ARG 37  37  ?   ?   ?   B . n 
B 1 38  PRO 38  38  ?   ?   ?   B . n 
B 1 39  SER 39  39  ?   ?   ?   B . n 
B 1 40  ARG 40  40  ?   ?   ?   B . n 
B 1 41  TYR 41  41  ?   ?   ?   B . n 
B 1 42  TYR 42  42  ?   ?   ?   B . n 
B 1 43  PRO 43  43  ?   ?   ?   B . n 
B 1 44  THR 44  44  ?   ?   ?   B . n 
B 1 45  TRP 45  45  ?   ?   ?   B . n 
B 1 46  LEU 46  46  ?   ?   ?   B . n 
B 1 47  PRO 47  47  ?   ?   ?   B . n 
B 1 48  SER 48  48  48  SER SER B . n 
B 1 49  ARG 49  49  49  ARG ARG B . n 
B 1 50  SER 50  50  50  SER SER B . n 
B 1 51  PHE 51  51  51  PHE PHE B . n 
B 1 52  ILE 52  52  52  ILE ILE B . n 
B 1 53  ALA 53  53  53  ALA ALA B . n 
B 1 54  ALA 54  54  54  ALA ALA B . n 
B 1 55  VAL 55  55  55  VAL VAL B . n 
B 1 56  ILE 56  56  56  ILE ILE B . n 
B 1 57  ALA 57  57  57  ALA ALA B . n 
B 1 58  ILE 58  58  58  ILE ILE B . n 
B 1 59  GLY 59  59  59  GLY GLY B . n 
B 1 60  GLY 60  60  60  GLY GLY B . n 
B 1 61  MET 61  61  61  MET MET B . n 
B 1 62  GLN 62  62  62  GLN GLN B . n 
B 1 63  LEU 63  63  63  LEU LEU B . n 
B 1 64  LEU 64  64  64  LEU LEU B . n 
B 1 65  ALA 65  65  65  ALA ALA B . n 
B 1 66  THR 66  66  66  THR THR B . n 
B 1 67  MET 67  67  67  MET MET B . n 
B 1 68  ASP 68  68  68  ASP ASP B . n 
B 1 69  SER 69  69  69  SER SER B . n 
B 1 70  THR 70  70  70  THR THR B . n 
B 1 71  VAL 71  71  71  VAL VAL B . n 
B 1 72  ALA 72  72  72  ALA ALA B . n 
B 1 73  ILE 73  73  73  ILE ILE B . n 
B 1 74  VAL 74  74  74  VAL VAL B . n 
B 1 75  ALA 75  75  75  ALA ALA B . n 
B 1 76  LEU 76  76  76  LEU LEU B . n 
B 1 77  PRO 77  77  77  PRO PRO B . n 
B 1 78  LYS 78  78  78  LYS LYS B . n 
B 1 79  ILE 79  79  79  ILE ILE B . n 
B 1 80  GLN 80  80  80  GLN GLN B . n 
B 1 81  ASN 81  81  81  ASN ASN B . n 
B 1 82  GLU 82  82  82  GLU GLU B . n 
B 1 83  LEU 83  83  83  LEU LEU B . n 
B 1 84  SER 84  84  84  SER SER B . n 
B 1 85  LEU 85  85  85  LEU LEU B . n 
B 1 86  SER 86  86  86  SER SER B . n 
B 1 87  ASP 87  87  87  ASP ASP B . n 
B 1 88  ALA 88  88  88  ALA ALA B . n 
B 1 89  GLY 89  89  89  GLY GLY B . n 
B 1 90  ARG 90  90  90  ARG ARG B . n 
B 1 91  SER 91  91  91  SER SER B . n 
B 1 92  TRP 92  92  92  TRP TRP B . n 
B 1 93  VAL 93  93  93  VAL VAL B . n 
B 1 94  ILE 94  94  94  ILE ILE B . n 
B 1 95  THR 95  95  95  THR THR B . n 
B 1 96  ALA 96  96  96  ALA ALA B . n 
B 1 97  TYR 97  97  97  TYR TYR B . n 
B 1 98  VAL 98  98  98  VAL VAL B . n 
B 1 99  LEU 99  99  99  LEU LEU B . n 
B 1 100 THR 100 100 100 THR THR B . n 
B 1 101 PHE 101 101 101 PHE PHE B . n 
B 1 102 GLY 102 102 102 GLY GLY B . n 
B 1 103 GLY 103 103 103 GLY GLY B . n 
B 1 104 LEU 104 104 104 LEU LEU B . n 
B 1 105 MET 105 105 105 MET MET B . n 
B 1 106 LEU 106 106 106 LEU LEU B . n 
B 1 107 LEU 107 107 107 LEU LEU B . n 
B 1 108 GLY 108 108 108 GLY GLY B . n 
B 1 109 GLY 109 109 109 GLY GLY B . n 
B 1 110 ARG 110 110 110 ARG ARG B . n 
B 1 111 LEU 111 111 111 LEU LEU B . n 
B 1 112 GLY 112 112 112 GLY GLY B . n 
B 1 113 ASP 113 113 113 ASP ASP B . n 
B 1 114 THR 114 114 114 THR THR B . n 
B 1 115 ILE 115 115 115 ILE ILE B . n 
B 1 116 GLY 116 116 116 GLY GLY B . n 
B 1 117 ARG 117 117 117 ARG ARG B . n 
B 1 118 LYS 118 118 118 LYS LYS B . n 
B 1 119 ARG 119 119 119 ARG ARG B . n 
B 1 120 THR 120 120 120 THR THR B . n 
B 1 121 PHE 121 121 121 PHE PHE B . n 
B 1 122 ILE 122 122 122 ILE ILE B . n 
B 1 123 VAL 123 123 123 VAL VAL B . n 
B 1 124 GLY 124 124 124 GLY GLY B . n 
B 1 125 VAL 125 125 125 VAL VAL B . n 
B 1 126 ALA 126 126 126 ALA ALA B . n 
B 1 127 LEU 127 127 127 LEU LEU B . n 
B 1 128 PHE 128 128 128 PHE PHE B . n 
B 1 129 THR 129 129 129 THR THR B . n 
B 1 130 ILE 130 130 130 ILE ILE B . n 
B 1 131 SER 131 131 131 SER SER B . n 
B 1 132 SER 132 132 132 SER SER B . n 
B 1 133 VAL 133 133 133 VAL VAL B . n 
B 1 134 LEU 134 134 134 LEU LEU B . n 
B 1 135 CYS 135 135 135 CYS CYS B . n 
B 1 136 ALA 136 136 136 ALA ALA B . n 
B 1 137 VAL 137 137 137 VAL VAL B . n 
B 1 138 ALA 138 138 138 ALA ALA B . n 
B 1 139 TRP 139 139 139 TRP TRP B . n 
B 1 140 ASP 140 140 140 ASP ASP B . n 
B 1 141 GLU 141 141 141 GLU GLU B . n 
B 1 142 ALA 142 142 142 ALA ALA B . n 
B 1 143 THR 143 143 143 THR THR B . n 
B 1 144 LEU 144 144 144 LEU LEU B . n 
B 1 145 VAL 145 145 145 VAL VAL B . n 
B 1 146 ILE 146 146 146 ILE ILE B . n 
B 1 147 ALA 147 147 147 ALA ALA B . n 
B 1 148 ARG 148 148 148 ARG ARG B . n 
B 1 149 LEU 149 149 149 LEU LEU B . n 
B 1 150 SER 150 150 150 SER SER B . n 
B 1 151 GLN 151 151 151 GLN GLN B . n 
B 1 152 GLY 152 152 152 GLY GLY B . n 
B 1 153 VAL 153 153 153 VAL VAL B . n 
B 1 154 GLY 154 154 154 GLY GLY B . n 
B 1 155 SER 155 155 155 SER SER B . n 
B 1 156 ALA 156 156 156 ALA ALA B . n 
B 1 157 ILE 157 157 157 ILE ILE B . n 
B 1 158 ALA 158 158 158 ALA ALA B . n 
B 1 159 SER 159 159 159 SER SER B . n 
B 1 160 PRO 160 160 160 PRO PRO B . n 
B 1 161 THR 161 161 161 THR THR B . n 
B 1 162 GLY 162 162 162 GLY GLY B . n 
B 1 163 LEU 163 163 163 LEU LEU B . n 
B 1 164 ALA 164 164 164 ALA ALA B . n 
B 1 165 LEU 165 165 165 LEU LEU B . n 
B 1 166 VAL 166 166 166 VAL VAL B . n 
B 1 167 ALA 167 167 167 ALA ALA B . n 
B 1 168 THR 168 168 168 THR THR B . n 
B 1 169 THR 169 169 169 THR THR B . n 
B 1 170 PHE 170 170 170 PHE PHE B . n 
B 1 171 PRO 171 171 171 PRO PRO B . n 
B 1 172 LYS 172 172 172 LYS LYS B . n 
B 1 173 GLY 173 173 173 GLY GLY B . n 
B 1 174 PRO 174 174 174 PRO PRO B . n 
B 1 175 ALA 175 175 175 ALA ALA B . n 
B 1 176 ARG 176 176 176 ARG ARG B . n 
B 1 177 ASN 177 177 177 ASN ASN B . n 
B 1 178 ALA 178 178 178 ALA ALA B . n 
B 1 179 ALA 179 179 179 ALA ALA B . n 
B 1 180 THR 180 180 180 THR THR B . n 
B 1 181 ALA 181 181 181 ALA ALA B . n 
B 1 182 VAL 182 182 182 VAL VAL B . n 
B 1 183 PHE 183 183 183 PHE PHE B . n 
B 1 184 ALA 184 184 184 ALA ALA B . n 
B 1 185 ALA 185 185 185 ALA ALA B . n 
B 1 186 MET 186 186 186 MET MET B . n 
B 1 187 THR 187 187 187 THR THR B . n 
B 1 188 ALA 188 188 188 ALA ALA B . n 
B 1 189 ILE 189 189 189 ILE ILE B . n 
B 1 190 GLY 190 190 190 GLY GLY B . n 
B 1 191 SER 191 191 191 SER SER B . n 
B 1 192 VAL 192 192 192 VAL VAL B . n 
B 1 193 MET 193 193 193 MET MET B . n 
B 1 194 GLY 194 194 194 GLY GLY B . n 
B 1 195 LEU 195 195 195 LEU LEU B . n 
B 1 196 VAL 196 196 196 VAL VAL B . n 
B 1 197 VAL 197 197 197 VAL VAL B . n 
B 1 198 GLY 198 198 198 GLY GLY B . n 
B 1 199 GLY 199 199 199 GLY GLY B . n 
B 1 200 ALA 200 200 200 ALA ALA B . n 
B 1 201 LEU 201 201 201 LEU LEU B . n 
B 1 202 THR 202 202 202 THR THR B . n 
B 1 203 GLU 203 203 203 GLU GLU B . n 
B 1 204 VAL 204 204 204 VAL VAL B . n 
B 1 205 SER 205 205 205 SER SER B . n 
B 1 206 TRP 206 206 206 TRP TRP B . n 
B 1 207 ARG 207 207 207 ARG ARG B . n 
B 1 208 TRP 208 208 208 TRP TRP B . n 
B 1 209 ALA 209 209 209 ALA ALA B . n 
B 1 210 PHE 210 210 210 PHE PHE B . n 
B 1 211 LEU 211 211 211 LEU LEU B . n 
B 1 212 VAL 212 212 212 VAL VAL B . n 
B 1 213 ASN 213 213 213 ASN ASN B . n 
B 1 214 VAL 214 214 214 VAL VAL B . n 
B 1 215 PRO 215 215 215 PRO PRO B . n 
B 1 216 ILE 216 216 216 ILE ILE B . n 
B 1 217 GLY 217 217 217 GLY GLY B . n 
B 1 218 LEU 218 218 218 LEU LEU B . n 
B 1 219 VAL 219 219 219 VAL VAL B . n 
B 1 220 MET 220 220 220 MET MET B . n 
B 1 221 ILE 221 221 221 ILE ILE B . n 
B 1 222 TYR 222 222 222 TYR TYR B . n 
B 1 223 LEU 223 223 223 LEU LEU B . n 
B 1 224 ALA 224 224 224 ALA ALA B . n 
B 1 225 ARG 225 225 225 ARG ARG B . n 
B 1 226 THR 226 226 226 THR THR B . n 
B 1 227 ALA 227 227 227 ALA ALA B . n 
B 1 228 LEU 228 228 228 LEU LEU B . n 
B 1 229 ARG 229 229 229 ARG ARG B . n 
B 1 230 GLU 230 230 230 GLU GLU B . n 
B 1 231 THR 231 231 231 THR THR B . n 
B 1 232 ASN 232 232 232 ASN ASN B . n 
B 1 233 LYS 233 233 233 LYS LYS B . n 
B 1 234 GLU 234 234 234 GLU GLU B . n 
B 1 235 ARG 235 235 235 ARG ARG B . n 
B 1 236 MET 236 236 236 MET MET B . n 
B 1 237 LYS 237 237 237 LYS LYS B . n 
B 1 238 LEU 238 238 238 LEU LEU B . n 
B 1 239 ASP 239 239 239 ASP ASP B . n 
B 1 240 ALA 240 240 240 ALA ALA B . n 
B 1 241 THR 241 241 241 THR THR B . n 
B 1 242 GLY 242 242 242 GLY GLY B . n 
B 1 243 ALA 243 243 243 ALA ALA B . n 
B 1 244 ILE 244 244 244 ILE ILE B . n 
B 1 245 LEU 245 245 245 LEU LEU B . n 
B 1 246 ALA 246 246 246 ALA ALA B . n 
B 1 247 THR 247 247 247 THR THR B . n 
B 1 248 LEU 248 248 248 LEU LEU B . n 
B 1 249 ALA 249 249 249 ALA ALA B . n 
B 1 250 CYS 250 250 250 CYS CYS B . n 
B 1 251 THR 251 251 251 THR THR B . n 
B 1 252 ALA 252 252 252 ALA ALA B . n 
B 1 253 ALA 253 253 253 ALA ALA B . n 
B 1 254 VAL 254 254 254 VAL VAL B . n 
B 1 255 PHE 255 255 255 PHE PHE B . n 
B 1 256 ALA 256 256 256 ALA ALA B . n 
B 1 257 PHE 257 257 257 PHE PHE B . n 
B 1 258 SER 258 258 258 SER SER B . n 
B 1 259 ILE 259 259 259 ILE ILE B . n 
B 1 260 GLY 260 260 260 GLY GLY B . n 
B 1 261 PRO 261 261 261 PRO PRO B . n 
B 1 262 GLU 262 262 262 GLU GLU B . n 
B 1 263 LYS 263 263 263 LYS LYS B . n 
B 1 264 GLY 264 264 264 GLY GLY B . n 
B 1 265 TRP 265 265 265 TRP TRP B . n 
B 1 266 MET 266 266 266 MET MET B . n 
B 1 267 SER 267 267 267 SER SER B . n 
B 1 268 GLY 268 268 268 GLY GLY B . n 
B 1 269 ILE 269 269 269 ILE ILE B . n 
B 1 270 THR 270 270 270 THR THR B . n 
B 1 271 ILE 271 271 271 ILE ILE B . n 
B 1 272 GLY 272 272 272 GLY GLY B . n 
B 1 273 SER 273 273 273 SER SER B . n 
B 1 274 GLY 274 274 274 GLY GLY B . n 
B 1 275 LEU 275 275 275 LEU LEU B . n 
B 1 276 VAL 276 276 276 VAL VAL B . n 
B 1 277 ALA 277 277 277 ALA ALA B . n 
B 1 278 LEU 278 278 278 LEU LEU B . n 
B 1 279 ALA 279 279 279 ALA ALA B . n 
B 1 280 ALA 280 280 280 ALA ALA B . n 
B 1 281 ALA 281 281 281 ALA ALA B . n 
B 1 282 VAL 282 282 282 VAL VAL B . n 
B 1 283 ALA 283 283 283 ALA ALA B . n 
B 1 284 PHE 284 284 284 PHE PHE B . n 
B 1 285 VAL 285 285 285 VAL VAL B . n 
B 1 286 ILE 286 286 286 ILE ILE B . n 
B 1 287 VAL 287 287 287 VAL VAL B . n 
B 1 288 GLU 288 288 288 GLU GLU B . n 
B 1 289 ARG 289 289 289 ARG ARG B . n 
B 1 290 THR 290 290 290 THR THR B . n 
B 1 291 ALA 291 291 291 ALA ALA B . n 
B 1 292 GLU 292 292 292 GLU GLU B . n 
B 1 293 ASN 293 293 293 ASN ASN B . n 
B 1 294 PRO 294 294 294 PRO PRO B . n 
B 1 295 VAL 295 295 295 VAL VAL B . n 
B 1 296 VAL 296 296 296 VAL VAL B . n 
B 1 297 PRO 297 297 297 PRO PRO B . n 
B 1 298 PHE 298 298 298 PHE PHE B . n 
B 1 299 HIS 299 299 299 HIS HIS B . n 
B 1 300 LEU 300 300 300 LEU LEU B . n 
B 1 301 PHE 301 301 301 PHE PHE B . n 
B 1 302 ARG 302 302 302 ARG ARG B . n 
B 1 303 ASP 303 303 303 ASP ASP B . n 
B 1 304 ARG 304 304 304 ARG ARG B . n 
B 1 305 ASN 305 305 305 ASN ASN B . n 
B 1 306 ARG 306 306 306 ARG ARG B . n 
B 1 307 LEU 307 307 307 LEU LEU B . n 
B 1 308 VAL 308 308 308 VAL VAL B . n 
B 1 309 THR 309 309 309 THR THR B . n 
B 1 310 PHE 310 310 310 PHE PHE B . n 
B 1 311 SER 311 311 311 SER SER B . n 
B 1 312 ALA 312 312 312 ALA ALA B . n 
B 1 313 ILE 313 313 313 ILE ILE B . n 
B 1 314 LEU 314 314 314 LEU LEU B . n 
B 1 315 LEU 315 315 315 LEU LEU B . n 
B 1 316 ALA 316 316 316 ALA ALA B . n 
B 1 317 GLY 317 317 317 GLY GLY B . n 
B 1 318 GLY 318 318 318 GLY GLY B . n 
B 1 319 VAL 319 319 319 VAL VAL B . n 
B 1 320 MET 320 320 320 MET MET B . n 
B 1 321 PHE 321 321 321 PHE PHE B . n 
B 1 322 SER 322 322 322 SER SER B . n 
B 1 323 LEU 323 323 323 LEU LEU B . n 
B 1 324 THR 324 324 324 THR THR B . n 
B 1 325 VAL 325 325 325 VAL VAL B . n 
B 1 326 CYS 326 326 326 CYS CYS B . n 
B 1 327 ILE 327 327 327 ILE ILE B . n 
B 1 328 GLY 328 328 328 GLY GLY B . n 
B 1 329 LEU 329 329 329 LEU LEU B . n 
B 1 330 TYR 330 330 330 TYR TYR B . n 
B 1 331 VAL 331 331 331 VAL VAL B . n 
B 1 332 GLN 332 332 332 GLN GLN B . n 
B 1 333 ASP 333 333 333 ASP ASP B . n 
B 1 334 ILE 334 334 334 ILE ILE B . n 
B 1 335 LEU 335 335 335 LEU LEU B . n 
B 1 336 GLY 336 336 336 GLY GLY B . n 
B 1 337 TYR 337 337 337 TYR TYR B . n 
B 1 338 SER 338 338 338 SER SER B . n 
B 1 339 ALA 339 339 339 ALA ALA B . n 
B 1 340 LEU 340 340 340 LEU LEU B . n 
B 1 341 ARG 341 341 341 ARG ARG B . n 
B 1 342 ALA 342 342 342 ALA ALA B . n 
B 1 343 GLY 343 343 343 GLY GLY B . n 
B 1 344 VAL 344 344 344 VAL VAL B . n 
B 1 345 GLY 345 345 345 GLY GLY B . n 
B 1 346 PHE 346 346 346 PHE PHE B . n 
B 1 347 ILE 347 347 347 ILE ILE B . n 
B 1 348 PRO 348 348 348 PRO PRO B . n 
B 1 349 PHE 349 349 349 PHE PHE B . n 
B 1 350 VAL 350 350 350 VAL VAL B . n 
B 1 351 ILE 351 351 351 ILE ILE B . n 
B 1 352 ALA 352 352 352 ALA ALA B . n 
B 1 353 MET 353 353 353 MET MET B . n 
B 1 354 GLY 354 354 354 GLY GLY B . n 
B 1 355 ILE 355 355 355 ILE ILE B . n 
B 1 356 GLY 356 356 356 GLY GLY B . n 
B 1 357 LEU 357 357 357 LEU LEU B . n 
B 1 358 GLY 358 358 358 GLY GLY B . n 
B 1 359 VAL 359 359 359 VAL VAL B . n 
B 1 360 SER 360 360 360 SER SER B . n 
B 1 361 SER 361 361 361 SER SER B . n 
B 1 362 GLN 362 362 362 GLN GLN B . n 
B 1 363 LEU 363 363 363 LEU LEU B . n 
B 1 364 VAL 364 364 364 VAL VAL B . n 
B 1 365 SER 365 365 365 SER SER B . n 
B 1 366 ARG 366 366 366 ARG ARG B . n 
B 1 367 PHE 367 367 367 PHE PHE B . n 
B 1 368 SER 368 368 368 SER SER B . n 
B 1 369 PRO 369 369 369 PRO PRO B . n 
B 1 370 ARG 370 370 370 ARG ARG B . n 
B 1 371 VAL 371 371 371 VAL VAL B . n 
B 1 372 LEU 372 372 372 LEU LEU B . n 
B 1 373 THR 373 373 373 THR THR B . n 
B 1 374 ILE 374 374 374 ILE ILE B . n 
B 1 375 GLY 375 375 375 GLY GLY B . n 
B 1 376 GLY 376 376 376 GLY GLY B . n 
B 1 377 GLY 377 377 377 GLY GLY B . n 
B 1 378 TYR 378 378 378 TYR TYR B . n 
B 1 379 LEU 379 379 379 LEU LEU B . n 
B 1 380 LEU 380 380 380 LEU LEU B . n 
B 1 381 PHE 381 381 381 PHE PHE B . n 
B 1 382 GLY 382 382 382 GLY GLY B . n 
B 1 383 ALA 383 383 383 ALA ALA B . n 
B 1 384 MET 384 384 384 MET MET B . n 
B 1 385 LEU 385 385 385 LEU LEU B . n 
B 1 386 TYR 386 386 386 TYR TYR B . n 
B 1 387 GLY 387 387 387 GLY GLY B . n 
B 1 388 SER 388 388 388 SER SER B . n 
B 1 389 PHE 389 389 389 PHE PHE B . n 
B 1 390 PHE 390 390 390 PHE PHE B . n 
B 1 391 MET 391 391 391 MET MET B . n 
B 1 392 HIS 392 392 392 HIS HIS B . n 
B 1 393 ARG 393 393 393 ARG ARG B . n 
B 1 394 GLY 394 394 394 GLY GLY B . n 
B 1 395 VAL 395 395 395 VAL VAL B . n 
B 1 396 PRO 396 396 396 PRO PRO B . n 
B 1 397 TYR 397 397 397 TYR TYR B . n 
B 1 398 PHE 398 398 398 PHE PHE B . n 
B 1 399 PRO 399 399 399 PRO PRO B . n 
B 1 400 ASN 400 400 400 ASN ASN B . n 
B 1 401 LEU 401 401 401 LEU LEU B . n 
B 1 402 VAL 402 402 402 VAL VAL B . n 
B 1 403 MET 403 403 403 MET MET B . n 
B 1 404 PRO 404 404 404 PRO PRO B . n 
B 1 405 ILE 405 405 405 ILE ILE B . n 
B 1 406 VAL 406 406 406 VAL VAL B . n 
B 1 407 VAL 407 407 407 VAL VAL B . n 
B 1 408 GLY 408 408 408 GLY GLY B . n 
B 1 409 GLY 409 409 409 GLY GLY B . n 
B 1 410 ILE 410 410 410 ILE ILE B . n 
B 1 411 GLY 411 411 411 GLY GLY B . n 
B 1 412 ILE 412 412 412 ILE ILE B . n 
B 1 413 GLY 413 413 413 GLY GLY B . n 
B 1 414 MET 414 414 414 MET MET B . n 
B 1 415 ALA 415 415 415 ALA ALA B . n 
B 1 416 VAL 416 416 416 VAL VAL B . n 
B 1 417 VAL 417 417 417 VAL VAL B . n 
B 1 418 PRO 418 418 418 PRO PRO B . n 
B 1 419 LEU 419 419 419 LEU LEU B . n 
B 1 420 THR 420 420 420 THR THR B . n 
B 1 421 LEU 421 421 421 LEU LEU B . n 
B 1 422 SER 422 422 422 SER SER B . n 
B 1 423 ALA 423 423 423 ALA ALA B . n 
B 1 424 ILE 424 424 424 ILE ILE B . n 
B 1 425 ALA 425 425 425 ALA ALA B . n 
B 1 426 GLY 426 426 426 GLY GLY B . n 
B 1 427 VAL 427 427 427 VAL VAL B . n 
B 1 428 GLY 428 428 428 GLY GLY B . n 
B 1 429 PHE 429 429 429 PHE PHE B . n 
B 1 430 ASP 430 430 430 ASP ASP B . n 
B 1 431 GLN 431 431 431 GLN GLN B . n 
B 1 432 ILE 432 432 432 ILE ILE B . n 
B 1 433 GLY 433 433 433 GLY GLY B . n 
B 1 434 PRO 434 434 434 PRO PRO B . n 
B 1 435 VAL 435 435 435 VAL VAL B . n 
B 1 436 SER 436 436 436 SER SER B . n 
B 1 437 ALA 437 437 437 ALA ALA B . n 
B 1 438 ILE 438 438 438 ILE ILE B . n 
B 1 439 ALA 439 439 439 ALA ALA B . n 
B 1 440 LEU 440 440 440 LEU LEU B . n 
B 1 441 MET 441 441 441 MET MET B . n 
B 1 442 LEU 442 442 442 LEU LEU B . n 
B 1 443 GLN 443 443 443 GLN GLN B . n 
B 1 444 SER 444 444 444 SER SER B . n 
B 1 445 LEU 445 445 445 LEU LEU B . n 
B 1 446 GLY 446 446 446 GLY GLY B . n 
B 1 447 GLY 447 447 447 GLY GLY B . n 
B 1 448 PRO 448 448 448 PRO PRO B . n 
B 1 449 LEU 449 449 449 LEU LEU B . n 
B 1 450 VAL 450 450 450 VAL VAL B . n 
B 1 451 LEU 451 451 451 LEU LEU B . n 
B 1 452 ALA 452 452 452 ALA ALA B . n 
B 1 453 VAL 453 453 453 VAL VAL B . n 
B 1 454 ILE 454 454 454 ILE ILE B . n 
B 1 455 GLN 455 455 455 GLN GLN B . n 
B 1 456 ALA 456 456 456 ALA ALA B . n 
B 1 457 VAL 457 457 457 VAL VAL B . n 
B 1 458 ILE 458 458 458 ILE ILE B . n 
B 1 459 THR 459 459 459 THR THR B . n 
B 1 460 SER 460 460 460 SER SER B . n 
B 1 461 ARG 461 461 461 ARG ARG B . n 
B 1 462 THR 462 462 462 THR THR B . n 
B 1 463 LEU 463 463 463 LEU LEU B . n 
B 1 464 TYR 464 464 464 TYR TYR B . n 
B 1 465 LEU 465 465 465 LEU LEU B . n 
B 1 466 GLY 466 466 466 GLY GLY B . n 
B 1 467 GLY 467 467 467 GLY GLY B . n 
B 1 468 THR 468 468 468 THR THR B . n 
B 1 469 THR 469 469 469 THR THR B . n 
B 1 470 GLY 470 470 470 GLY GLY B . n 
B 1 471 PRO 471 471 471 PRO PRO B . n 
B 1 472 VAL 472 472 472 VAL VAL B . n 
B 1 473 LYS 473 473 473 LYS LYS B . n 
B 1 474 PHE 474 474 474 PHE PHE B . n 
B 1 475 MET 475 475 475 MET MET B . n 
B 1 476 ASN 476 476 476 ASN ASN B . n 
B 1 477 ASP 477 477 477 ASP ASP B . n 
B 1 478 VAL 478 478 478 VAL VAL B . n 
B 1 479 GLN 479 479 479 GLN GLN B . n 
B 1 480 LEU 480 480 480 LEU LEU B . n 
B 1 481 ALA 481 481 481 ALA ALA B . n 
B 1 482 ALA 482 482 482 ALA ALA B . n 
B 1 483 LEU 483 483 483 LEU LEU B . n 
B 1 484 ASP 484 484 484 ASP ASP B . n 
B 1 485 HIS 485 485 485 HIS HIS B . n 
B 1 486 ALA 486 486 486 ALA ALA B . n 
B 1 487 TYR 487 487 487 TYR TYR B . n 
B 1 488 THR 488 488 488 THR THR B . n 
B 1 489 TYR 489 489 489 TYR TYR B . n 
B 1 490 GLY 490 490 490 GLY GLY B . n 
B 1 491 LEU 491 491 491 LEU LEU B . n 
B 1 492 LEU 492 492 492 LEU LEU B . n 
B 1 493 TRP 493 493 493 TRP TRP B . n 
B 1 494 VAL 494 494 494 VAL VAL B . n 
B 1 495 ALA 495 495 495 ALA ALA B . n 
B 1 496 GLY 496 496 496 GLY GLY B . n 
B 1 497 ALA 497 497 497 ALA ALA B . n 
B 1 498 ALA 498 498 498 ALA ALA B . n 
B 1 499 ILE 499 499 499 ILE ILE B . n 
B 1 500 ILE 500 500 500 ILE ILE B . n 
B 1 501 VAL 501 501 501 VAL VAL B . n 
B 1 502 GLY 502 502 502 GLY GLY B . n 
B 1 503 GLY 503 503 503 GLY GLY B . n 
B 1 504 MET 504 504 504 MET MET B . n 
B 1 505 ALA 505 505 505 ALA ALA B . n 
B 1 506 LEU 506 506 506 LEU LEU B . n 
B 1 507 PHE 507 507 507 PHE PHE B . n 
B 1 508 ILE 508 508 508 ILE ILE B . n 
B 1 509 GLY 509 509 509 GLY GLY B . n 
B 1 510 TYR 510 510 510 TYR TYR B . n 
B 1 511 THR 511 511 511 THR THR B . n 
B 1 512 PRO 512 512 512 PRO PRO B . n 
B 1 513 GLN 513 513 513 GLN GLN B . n 
B 1 514 GLN 514 514 514 GLN GLN B . n 
B 1 515 VAL 515 515 515 VAL VAL B . n 
B 1 516 ALA 516 516 516 ALA ALA B . n 
B 1 517 HIS 517 517 517 HIS HIS B . n 
B 1 518 ALA 518 518 518 ALA ALA B . n 
B 1 519 GLN 519 519 519 GLN GLN B . n 
B 1 520 GLU 520 520 ?   ?   ?   B . n 
B 1 521 VAL 521 521 ?   ?   ?   B . n 
B 1 522 LYS 522 522 ?   ?   ?   B . n 
B 1 523 GLU 523 523 ?   ?   ?   B . n 
B 1 524 ALA 524 524 ?   ?   ?   B . n 
B 1 525 ILE 525 525 ?   ?   ?   B . n 
B 1 526 ASP 526 526 ?   ?   ?   B . n 
B 1 527 ALA 527 527 ?   ?   ?   B . n 
B 1 528 GLY 528 528 ?   ?   ?   B . n 
B 1 529 GLU 529 529 ?   ?   ?   B . n 
B 1 530 LEU 530 530 ?   ?   ?   B . n 
B 1 531 ALA 531 531 ?   ?   ?   B . n 
B 1 532 ALA 532 532 ?   ?   ?   B . n 
B 1 533 ALA 533 533 ?   ?   ?   B . n 
B 1 534 GLU 534 534 ?   ?   ?   B . n 
B 1 535 ASN 535 535 ?   ?   ?   B . n 
B 1 536 LEU 536 536 ?   ?   ?   B . n 
B 1 537 TYR 537 537 ?   ?   ?   B . n 
B 1 538 PHE 538 538 ?   ?   ?   B . n 
B 1 539 GLN 539 539 ?   ?   ?   B . n 
B 1 540 GLY 540 540 ?   ?   ?   B . n 
B 1 541 LEU 541 541 ?   ?   ?   B . n 
B 1 542 TRP 542 542 ?   ?   ?   B . n 
B 1 543 SER 543 543 ?   ?   ?   B . n 
B 1 544 HIS 544 544 ?   ?   ?   B . n 
B 1 545 PRO 545 545 ?   ?   ?   B . n 
B 1 546 GLN 546 546 ?   ?   ?   B . n 
B 1 547 PHE 547 547 ?   ?   ?   B . n 
B 1 548 GLU 548 548 ?   ?   ?   B . n 
B 1 549 LYS 549 549 ?   ?   ?   B . n 
B 1 550 GLY 550 550 ?   ?   ?   B . n 
B 1 551 GLY 551 551 ?   ?   ?   B . n 
B 1 552 GLY 552 552 ?   ?   ?   B . n 
B 1 553 SER 553 553 ?   ?   ?   B . n 
B 1 554 GLY 554 554 ?   ?   ?   B . n 
B 1 555 GLY 555 555 ?   ?   ?   B . n 
B 1 556 GLY 556 556 ?   ?   ?   B . n 
B 1 557 SER 557 557 ?   ?   ?   B . n 
B 1 558 GLY 558 558 ?   ?   ?   B . n 
B 1 559 GLY 559 559 ?   ?   ?   B . n 
B 1 560 SER 560 560 ?   ?   ?   B . n 
B 1 561 ALA 561 561 ?   ?   ?   B . n 
B 1 562 TRP 562 562 ?   ?   ?   B . n 
B 1 563 SER 563 563 ?   ?   ?   B . n 
B 1 564 HIS 564 564 ?   ?   ?   B . n 
B 1 565 PRO 565 565 ?   ?   ?   B . n 
B 1 566 GLN 566 566 ?   ?   ?   B . n 
B 1 567 PHE 567 567 ?   ?   ?   B . n 
B 1 568 GLU 568 568 ?   ?   ?   B . n 
B 1 569 LYS 569 569 ?   ?   ?   B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 Y86 ? ? Y86 ? ? 'SUBJECT OF INVESTIGATION' ? 
2 Y8F ? ? Y8F ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 Y86 1 601 601 Y86 LIG A . 
D 3 Y8F 1 602 1   Y8F LIP A . 
E 2 Y86 1 601 601 Y86 LIG B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8X6X 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8X6X 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8X6X 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               67.32 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8X6X 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               NONE 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.0033 ? 7154 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.5245 ? 9717 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 0.0374 ? 1188 ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.0042 ? 1190 ? f_plane_restr      ? ? 
'ELECTRON MICROSCOPY' ? 5.4057 ? 1115 ? f_dihedral_angle_d ? ? 
# 
_struct.entry_id                     8X6X 
_struct.title                        'Structure of the multidrug efflux pump EfpA from M. tuberculosis complexed with lipids' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8X6X 
_struct_keywords.text            'drug resistance MFS EfpA efflux pump, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    EFPA_MYCTU 
_struct_ref.pdbx_db_accession          P9WJY5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQ
NELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASP
TGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA
TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVM
FSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPN
LVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL
AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8X6X A 1 ? 530 ? P9WJY5 1 ? 530 ? 1 530 
2 1 8X6X B 1 ? 530 ? P9WJY5 1 ? 530 ? 1 530 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8X6X ALA A 531 ? UNP P9WJY5 ? ? 'expression tag' 531 1  
1 8X6X ALA A 532 ? UNP P9WJY5 ? ? 'expression tag' 532 2  
1 8X6X ALA A 533 ? UNP P9WJY5 ? ? 'expression tag' 533 3  
1 8X6X GLU A 534 ? UNP P9WJY5 ? ? 'expression tag' 534 4  
1 8X6X ASN A 535 ? UNP P9WJY5 ? ? 'expression tag' 535 5  
1 8X6X LEU A 536 ? UNP P9WJY5 ? ? 'expression tag' 536 6  
1 8X6X TYR A 537 ? UNP P9WJY5 ? ? 'expression tag' 537 7  
1 8X6X PHE A 538 ? UNP P9WJY5 ? ? 'expression tag' 538 8  
1 8X6X GLN A 539 ? UNP P9WJY5 ? ? 'expression tag' 539 9  
1 8X6X GLY A 540 ? UNP P9WJY5 ? ? 'expression tag' 540 10 
1 8X6X LEU A 541 ? UNP P9WJY5 ? ? 'expression tag' 541 11 
1 8X6X TRP A 542 ? UNP P9WJY5 ? ? 'expression tag' 542 12 
1 8X6X SER A 543 ? UNP P9WJY5 ? ? 'expression tag' 543 13 
1 8X6X HIS A 544 ? UNP P9WJY5 ? ? 'expression tag' 544 14 
1 8X6X PRO A 545 ? UNP P9WJY5 ? ? 'expression tag' 545 15 
1 8X6X GLN A 546 ? UNP P9WJY5 ? ? 'expression tag' 546 16 
1 8X6X PHE A 547 ? UNP P9WJY5 ? ? 'expression tag' 547 17 
1 8X6X GLU A 548 ? UNP P9WJY5 ? ? 'expression tag' 548 18 
1 8X6X LYS A 549 ? UNP P9WJY5 ? ? 'expression tag' 549 19 
1 8X6X GLY A 550 ? UNP P9WJY5 ? ? 'expression tag' 550 20 
1 8X6X GLY A 551 ? UNP P9WJY5 ? ? 'expression tag' 551 21 
1 8X6X GLY A 552 ? UNP P9WJY5 ? ? 'expression tag' 552 22 
1 8X6X SER A 553 ? UNP P9WJY5 ? ? 'expression tag' 553 23 
1 8X6X GLY A 554 ? UNP P9WJY5 ? ? 'expression tag' 554 24 
1 8X6X GLY A 555 ? UNP P9WJY5 ? ? 'expression tag' 555 25 
1 8X6X GLY A 556 ? UNP P9WJY5 ? ? 'expression tag' 556 26 
1 8X6X SER A 557 ? UNP P9WJY5 ? ? 'expression tag' 557 27 
1 8X6X GLY A 558 ? UNP P9WJY5 ? ? 'expression tag' 558 28 
1 8X6X GLY A 559 ? UNP P9WJY5 ? ? 'expression tag' 559 29 
1 8X6X SER A 560 ? UNP P9WJY5 ? ? 'expression tag' 560 30 
1 8X6X ALA A 561 ? UNP P9WJY5 ? ? 'expression tag' 561 31 
1 8X6X TRP A 562 ? UNP P9WJY5 ? ? 'expression tag' 562 32 
1 8X6X SER A 563 ? UNP P9WJY5 ? ? 'expression tag' 563 33 
1 8X6X HIS A 564 ? UNP P9WJY5 ? ? 'expression tag' 564 34 
1 8X6X PRO A 565 ? UNP P9WJY5 ? ? 'expression tag' 565 35 
1 8X6X GLN A 566 ? UNP P9WJY5 ? ? 'expression tag' 566 36 
1 8X6X PHE A 567 ? UNP P9WJY5 ? ? 'expression tag' 567 37 
1 8X6X GLU A 568 ? UNP P9WJY5 ? ? 'expression tag' 568 38 
1 8X6X LYS A 569 ? UNP P9WJY5 ? ? 'expression tag' 569 39 
2 8X6X ALA B 531 ? UNP P9WJY5 ? ? 'expression tag' 531 40 
2 8X6X ALA B 532 ? UNP P9WJY5 ? ? 'expression tag' 532 41 
2 8X6X ALA B 533 ? UNP P9WJY5 ? ? 'expression tag' 533 42 
2 8X6X GLU B 534 ? UNP P9WJY5 ? ? 'expression tag' 534 43 
2 8X6X ASN B 535 ? UNP P9WJY5 ? ? 'expression tag' 535 44 
2 8X6X LEU B 536 ? UNP P9WJY5 ? ? 'expression tag' 536 45 
2 8X6X TYR B 537 ? UNP P9WJY5 ? ? 'expression tag' 537 46 
2 8X6X PHE B 538 ? UNP P9WJY5 ? ? 'expression tag' 538 47 
2 8X6X GLN B 539 ? UNP P9WJY5 ? ? 'expression tag' 539 48 
2 8X6X GLY B 540 ? UNP P9WJY5 ? ? 'expression tag' 540 49 
2 8X6X LEU B 541 ? UNP P9WJY5 ? ? 'expression tag' 541 50 
2 8X6X TRP B 542 ? UNP P9WJY5 ? ? 'expression tag' 542 51 
2 8X6X SER B 543 ? UNP P9WJY5 ? ? 'expression tag' 543 52 
2 8X6X HIS B 544 ? UNP P9WJY5 ? ? 'expression tag' 544 53 
2 8X6X PRO B 545 ? UNP P9WJY5 ? ? 'expression tag' 545 54 
2 8X6X GLN B 546 ? UNP P9WJY5 ? ? 'expression tag' 546 55 
2 8X6X PHE B 547 ? UNP P9WJY5 ? ? 'expression tag' 547 56 
2 8X6X GLU B 548 ? UNP P9WJY5 ? ? 'expression tag' 548 57 
2 8X6X LYS B 549 ? UNP P9WJY5 ? ? 'expression tag' 549 58 
2 8X6X GLY B 550 ? UNP P9WJY5 ? ? 'expression tag' 550 59 
2 8X6X GLY B 551 ? UNP P9WJY5 ? ? 'expression tag' 551 60 
2 8X6X GLY B 552 ? UNP P9WJY5 ? ? 'expression tag' 552 61 
2 8X6X SER B 553 ? UNP P9WJY5 ? ? 'expression tag' 553 62 
2 8X6X GLY B 554 ? UNP P9WJY5 ? ? 'expression tag' 554 63 
2 8X6X GLY B 555 ? UNP P9WJY5 ? ? 'expression tag' 555 64 
2 8X6X GLY B 556 ? UNP P9WJY5 ? ? 'expression tag' 556 65 
2 8X6X SER B 557 ? UNP P9WJY5 ? ? 'expression tag' 557 66 
2 8X6X GLY B 558 ? UNP P9WJY5 ? ? 'expression tag' 558 67 
2 8X6X GLY B 559 ? UNP P9WJY5 ? ? 'expression tag' 559 68 
2 8X6X SER B 560 ? UNP P9WJY5 ? ? 'expression tag' 560 69 
2 8X6X ALA B 561 ? UNP P9WJY5 ? ? 'expression tag' 561 70 
2 8X6X TRP B 562 ? UNP P9WJY5 ? ? 'expression tag' 562 71 
2 8X6X SER B 563 ? UNP P9WJY5 ? ? 'expression tag' 563 72 
2 8X6X HIS B 564 ? UNP P9WJY5 ? ? 'expression tag' 564 73 
2 8X6X PRO B 565 ? UNP P9WJY5 ? ? 'expression tag' 565 74 
2 8X6X GLN B 566 ? UNP P9WJY5 ? ? 'expression tag' 566 75 
2 8X6X PHE B 567 ? UNP P9WJY5 ? ? 'expression tag' 567 76 
2 8X6X GLU B 568 ? UNP P9WJY5 ? ? 'expression tag' 568 77 
2 8X6X LYS B 569 ? UNP P9WJY5 ? ? 'expression tag' 569 78 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 48  ? ALA A 75  ? SER A 48  ALA A 75  1 ? 28 
HELX_P HELX_P2  AA2 ALA A 75  ? SER A 84  ? ALA A 75  SER A 84  1 ? 10 
HELX_P HELX_P3  AA3 SER A 86  ? LEU A 104 ? SER A 86  LEU A 104 1 ? 19 
HELX_P HELX_P4  AA4 LEU A 104 ? GLY A 116 ? LEU A 104 GLY A 116 1 ? 13 
HELX_P HELX_P5  AA5 GLY A 116 ? VAL A 137 ? GLY A 116 VAL A 137 1 ? 22 
HELX_P HELX_P6  AA6 ASP A 140 ? PHE A 170 ? ASP A 140 PHE A 170 1 ? 31 
HELX_P HELX_P7  AA7 GLY A 173 ? THR A 202 ? GLY A 173 THR A 202 1 ? 30 
HELX_P HELX_P8  AA8 VAL A 212 ? LEU A 228 ? VAL A 212 LEU A 228 1 ? 17 
HELX_P HELX_P9  AA9 ASP A 239 ? GLY A 264 ? ASP A 239 GLY A 264 1 ? 26 
HELX_P HELX_P10 AB1 SER A 267 ? GLU A 288 ? SER A 267 GLU A 288 1 ? 22 
HELX_P HELX_P11 AB2 ARG A 289 ? ALA A 291 ? ARG A 289 ALA A 291 5 ? 3  
HELX_P HELX_P12 AB3 PHE A 298 ? ARG A 302 ? PHE A 298 ARG A 302 5 ? 5  
HELX_P HELX_P13 AB4 ASP A 303 ? ILE A 334 ? ASP A 303 ILE A 334 1 ? 32 
HELX_P HELX_P14 AB5 SER A 338 ? PHE A 346 ? SER A 338 PHE A 346 1 ? 9  
HELX_P HELX_P15 AB6 PHE A 346 ? VAL A 364 ? PHE A 346 VAL A 364 1 ? 19 
HELX_P HELX_P16 AB7 SER A 368 ? PHE A 390 ? SER A 368 PHE A 390 1 ? 23 
HELX_P HELX_P17 AB8 PRO A 396 ? LEU A 401 ? PRO A 396 LEU A 401 1 ? 6  
HELX_P HELX_P18 AB9 LEU A 401 ? ALA A 423 ? LEU A 401 ALA A 423 1 ? 23 
HELX_P HELX_P19 AC1 GLN A 431 ? LEU A 465 ? GLN A 431 LEU A 465 1 ? 35 
HELX_P HELX_P20 AC2 PRO A 471 ? MET A 475 ? PRO A 471 MET A 475 5 ? 5  
HELX_P HELX_P21 AC3 ASN A 476 ? LEU A 506 ? ASN A 476 LEU A 506 1 ? 31 
HELX_P HELX_P22 AC4 THR A 511 ? ALA A 516 ? THR A 511 ALA A 516 1 ? 6  
HELX_P HELX_P23 AC5 ARG B 49  ? ALA B 75  ? ARG B 49  ALA B 75  1 ? 27 
HELX_P HELX_P24 AC6 ALA B 75  ? SER B 84  ? ALA B 75  SER B 84  1 ? 10 
HELX_P HELX_P25 AC7 SER B 86  ? LEU B 104 ? SER B 86  LEU B 104 1 ? 19 
HELX_P HELX_P26 AC8 LEU B 104 ? GLY B 116 ? LEU B 104 GLY B 116 1 ? 13 
HELX_P HELX_P27 AC9 GLY B 116 ? ALA B 138 ? GLY B 116 ALA B 138 1 ? 23 
HELX_P HELX_P28 AD1 ASP B 140 ? PHE B 170 ? ASP B 140 PHE B 170 1 ? 31 
HELX_P HELX_P29 AD2 GLY B 173 ? LEU B 201 ? GLY B 173 LEU B 201 1 ? 29 
HELX_P HELX_P30 AD3 TRP B 206 ? LEU B 211 ? TRP B 206 LEU B 211 1 ? 6  
HELX_P HELX_P31 AD4 VAL B 212 ? ALA B 227 ? VAL B 212 ALA B 227 1 ? 16 
HELX_P HELX_P32 AD5 ASP B 239 ? GLY B 264 ? ASP B 239 GLY B 264 1 ? 26 
HELX_P HELX_P33 AD6 GLY B 268 ? GLU B 288 ? GLY B 268 GLU B 288 1 ? 21 
HELX_P HELX_P34 AD7 ARG B 289 ? ALA B 291 ? ARG B 289 ALA B 291 5 ? 3  
HELX_P HELX_P35 AD8 PRO B 297 ? ARG B 302 ? PRO B 297 ARG B 302 5 ? 6  
HELX_P HELX_P36 AD9 ASP B 303 ? ILE B 334 ? ASP B 303 ILE B 334 1 ? 32 
HELX_P HELX_P37 AE1 SER B 338 ? PHE B 346 ? SER B 338 PHE B 346 1 ? 9  
HELX_P HELX_P38 AE2 PHE B 346 ? VAL B 364 ? PHE B 346 VAL B 364 1 ? 19 
HELX_P HELX_P39 AE3 SER B 368 ? PHE B 390 ? SER B 368 PHE B 390 1 ? 23 
HELX_P HELX_P40 AE4 PRO B 396 ? ILE B 424 ? PRO B 396 ILE B 424 1 ? 29 
HELX_P HELX_P41 AE5 GLN B 431 ? GLY B 466 ? GLN B 431 GLY B 466 1 ? 36 
HELX_P HELX_P42 AE6 PRO B 471 ? MET B 475 ? PRO B 471 MET B 475 5 ? 5  
HELX_P HELX_P43 AE7 ASN B 476 ? LEU B 506 ? ASN B 476 LEU B 506 1 ? 31 
HELX_P HELX_P44 AE8 THR B 511 ? ALA B 516 ? THR B 511 ALA B 516 1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_pdbx_entry_details.entry_id                   8X6X 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OE1 
_pdbx_validate_close_contact.auth_asym_id_1   B 
_pdbx_validate_close_contact.auth_comp_id_1   GLU 
_pdbx_validate_close_contact.auth_seq_id_1    82 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   NE1 
_pdbx_validate_close_contact.auth_asym_id_2   B 
_pdbx_validate_close_contact.auth_comp_id_2   TRP 
_pdbx_validate_close_contact.auth_seq_id_2    206 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.14 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 VAL A 515 ? ? -121.58 -50.47 
2 1 VAL B 204 ? ? -90.67  -65.29 
3 1 MET B 266 ? ? 35.39   44.12  
4 1 ASN B 293 ? ? 52.61   70.42  
5 1 LEU B 506 ? ? -66.31  0.02   
# 
_space_group_symop.id              1 
_space_group_symop.operation_xyz   x,y,z 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8X6X 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8X6X 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.92 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               227843 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 EfpA 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8X6X 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             900 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8X6X 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8X6X 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A THR 2   ? A THR 2   
3   1 Y 1 A ALA 3   ? A ALA 3   
4   1 Y 1 A LEU 4   ? A LEU 4   
5   1 Y 1 A ASN 5   ? A ASN 5   
6   1 Y 1 A ASP 6   ? A ASP 6   
7   1 Y 1 A THR 7   ? A THR 7   
8   1 Y 1 A GLU 8   ? A GLU 8   
9   1 Y 1 A ARG 9   ? A ARG 9   
10  1 Y 1 A ALA 10  ? A ALA 10  
11  1 Y 1 A VAL 11  ? A VAL 11  
12  1 Y 1 A ARG 12  ? A ARG 12  
13  1 Y 1 A ASN 13  ? A ASN 13  
14  1 Y 1 A TRP 14  ? A TRP 14  
15  1 Y 1 A THR 15  ? A THR 15  
16  1 Y 1 A ALA 16  ? A ALA 16  
17  1 Y 1 A GLY 17  ? A GLY 17  
18  1 Y 1 A ARG 18  ? A ARG 18  
19  1 Y 1 A PRO 19  ? A PRO 19  
20  1 Y 1 A HIS 20  ? A HIS 20  
21  1 Y 1 A ARG 21  ? A ARG 21  
22  1 Y 1 A PRO 22  ? A PRO 22  
23  1 Y 1 A ALA 23  ? A ALA 23  
24  1 Y 1 A PRO 24  ? A PRO 24  
25  1 Y 1 A MET 25  ? A MET 25  
26  1 Y 1 A ARG 26  ? A ARG 26  
27  1 Y 1 A PRO 27  ? A PRO 27  
28  1 Y 1 A PRO 28  ? A PRO 28  
29  1 Y 1 A ARG 29  ? A ARG 29  
30  1 Y 1 A SER 30  ? A SER 30  
31  1 Y 1 A GLU 31  ? A GLU 31  
32  1 Y 1 A GLU 32  ? A GLU 32  
33  1 Y 1 A THR 33  ? A THR 33  
34  1 Y 1 A ALA 34  ? A ALA 34  
35  1 Y 1 A SER 35  ? A SER 35  
36  1 Y 1 A GLU 36  ? A GLU 36  
37  1 Y 1 A ARG 37  ? A ARG 37  
38  1 Y 1 A PRO 38  ? A PRO 38  
39  1 Y 1 A SER 39  ? A SER 39  
40  1 Y 1 A ARG 40  ? A ARG 40  
41  1 Y 1 A TYR 41  ? A TYR 41  
42  1 Y 1 A TYR 42  ? A TYR 42  
43  1 Y 1 A PRO 43  ? A PRO 43  
44  1 Y 1 A THR 44  ? A THR 44  
45  1 Y 1 A TRP 45  ? A TRP 45  
46  1 Y 1 A LEU 46  ? A LEU 46  
47  1 Y 1 A PRO 47  ? A PRO 47  
48  1 Y 1 A GLU 520 ? A GLU 520 
49  1 Y 1 A VAL 521 ? A VAL 521 
50  1 Y 1 A LYS 522 ? A LYS 522 
51  1 Y 1 A GLU 523 ? A GLU 523 
52  1 Y 1 A ALA 524 ? A ALA 524 
53  1 Y 1 A ILE 525 ? A ILE 525 
54  1 Y 1 A ASP 526 ? A ASP 526 
55  1 Y 1 A ALA 527 ? A ALA 527 
56  1 Y 1 A GLY 528 ? A GLY 528 
57  1 Y 1 A GLU 529 ? A GLU 529 
58  1 Y 1 A LEU 530 ? A LEU 530 
59  1 Y 1 A ALA 531 ? A ALA 531 
60  1 Y 1 A ALA 532 ? A ALA 532 
61  1 Y 1 A ALA 533 ? A ALA 533 
62  1 Y 1 A GLU 534 ? A GLU 534 
63  1 Y 1 A ASN 535 ? A ASN 535 
64  1 Y 1 A LEU 536 ? A LEU 536 
65  1 Y 1 A TYR 537 ? A TYR 537 
66  1 Y 1 A PHE 538 ? A PHE 538 
67  1 Y 1 A GLN 539 ? A GLN 539 
68  1 Y 1 A GLY 540 ? A GLY 540 
69  1 Y 1 A LEU 541 ? A LEU 541 
70  1 Y 1 A TRP 542 ? A TRP 542 
71  1 Y 1 A SER 543 ? A SER 543 
72  1 Y 1 A HIS 544 ? A HIS 544 
73  1 Y 1 A PRO 545 ? A PRO 545 
74  1 Y 1 A GLN 546 ? A GLN 546 
75  1 Y 1 A PHE 547 ? A PHE 547 
76  1 Y 1 A GLU 548 ? A GLU 548 
77  1 Y 1 A LYS 549 ? A LYS 549 
78  1 Y 1 A GLY 550 ? A GLY 550 
79  1 Y 1 A GLY 551 ? A GLY 551 
80  1 Y 1 A GLY 552 ? A GLY 552 
81  1 Y 1 A SER 553 ? A SER 553 
82  1 Y 1 A GLY 554 ? A GLY 554 
83  1 Y 1 A GLY 555 ? A GLY 555 
84  1 Y 1 A GLY 556 ? A GLY 556 
85  1 Y 1 A SER 557 ? A SER 557 
86  1 Y 1 A GLY 558 ? A GLY 558 
87  1 Y 1 A GLY 559 ? A GLY 559 
88  1 Y 1 A SER 560 ? A SER 560 
89  1 Y 1 A ALA 561 ? A ALA 561 
90  1 Y 1 A TRP 562 ? A TRP 562 
91  1 Y 1 A SER 563 ? A SER 563 
92  1 Y 1 A HIS 564 ? A HIS 564 
93  1 Y 1 A PRO 565 ? A PRO 565 
94  1 Y 1 A GLN 566 ? A GLN 566 
95  1 Y 1 A PHE 567 ? A PHE 567 
96  1 Y 1 A GLU 568 ? A GLU 568 
97  1 Y 1 A LYS 569 ? A LYS 569 
98  1 Y 1 B MET 1   ? B MET 1   
99  1 Y 1 B THR 2   ? B THR 2   
100 1 Y 1 B ALA 3   ? B ALA 3   
101 1 Y 1 B LEU 4   ? B LEU 4   
102 1 Y 1 B ASN 5   ? B ASN 5   
103 1 Y 1 B ASP 6   ? B ASP 6   
104 1 Y 1 B THR 7   ? B THR 7   
105 1 Y 1 B GLU 8   ? B GLU 8   
106 1 Y 1 B ARG 9   ? B ARG 9   
107 1 Y 1 B ALA 10  ? B ALA 10  
108 1 Y 1 B VAL 11  ? B VAL 11  
109 1 Y 1 B ARG 12  ? B ARG 12  
110 1 Y 1 B ASN 13  ? B ASN 13  
111 1 Y 1 B TRP 14  ? B TRP 14  
112 1 Y 1 B THR 15  ? B THR 15  
113 1 Y 1 B ALA 16  ? B ALA 16  
114 1 Y 1 B GLY 17  ? B GLY 17  
115 1 Y 1 B ARG 18  ? B ARG 18  
116 1 Y 1 B PRO 19  ? B PRO 19  
117 1 Y 1 B HIS 20  ? B HIS 20  
118 1 Y 1 B ARG 21  ? B ARG 21  
119 1 Y 1 B PRO 22  ? B PRO 22  
120 1 Y 1 B ALA 23  ? B ALA 23  
121 1 Y 1 B PRO 24  ? B PRO 24  
122 1 Y 1 B MET 25  ? B MET 25  
123 1 Y 1 B ARG 26  ? B ARG 26  
124 1 Y 1 B PRO 27  ? B PRO 27  
125 1 Y 1 B PRO 28  ? B PRO 28  
126 1 Y 1 B ARG 29  ? B ARG 29  
127 1 Y 1 B SER 30  ? B SER 30  
128 1 Y 1 B GLU 31  ? B GLU 31  
129 1 Y 1 B GLU 32  ? B GLU 32  
130 1 Y 1 B THR 33  ? B THR 33  
131 1 Y 1 B ALA 34  ? B ALA 34  
132 1 Y 1 B SER 35  ? B SER 35  
133 1 Y 1 B GLU 36  ? B GLU 36  
134 1 Y 1 B ARG 37  ? B ARG 37  
135 1 Y 1 B PRO 38  ? B PRO 38  
136 1 Y 1 B SER 39  ? B SER 39  
137 1 Y 1 B ARG 40  ? B ARG 40  
138 1 Y 1 B TYR 41  ? B TYR 41  
139 1 Y 1 B TYR 42  ? B TYR 42  
140 1 Y 1 B PRO 43  ? B PRO 43  
141 1 Y 1 B THR 44  ? B THR 44  
142 1 Y 1 B TRP 45  ? B TRP 45  
143 1 Y 1 B LEU 46  ? B LEU 46  
144 1 Y 1 B PRO 47  ? B PRO 47  
145 1 Y 1 B GLU 520 ? B GLU 520 
146 1 Y 1 B VAL 521 ? B VAL 521 
147 1 Y 1 B LYS 522 ? B LYS 522 
148 1 Y 1 B GLU 523 ? B GLU 523 
149 1 Y 1 B ALA 524 ? B ALA 524 
150 1 Y 1 B ILE 525 ? B ILE 525 
151 1 Y 1 B ASP 526 ? B ASP 526 
152 1 Y 1 B ALA 527 ? B ALA 527 
153 1 Y 1 B GLY 528 ? B GLY 528 
154 1 Y 1 B GLU 529 ? B GLU 529 
155 1 Y 1 B LEU 530 ? B LEU 530 
156 1 Y 1 B ALA 531 ? B ALA 531 
157 1 Y 1 B ALA 532 ? B ALA 532 
158 1 Y 1 B ALA 533 ? B ALA 533 
159 1 Y 1 B GLU 534 ? B GLU 534 
160 1 Y 1 B ASN 535 ? B ASN 535 
161 1 Y 1 B LEU 536 ? B LEU 536 
162 1 Y 1 B TYR 537 ? B TYR 537 
163 1 Y 1 B PHE 538 ? B PHE 538 
164 1 Y 1 B GLN 539 ? B GLN 539 
165 1 Y 1 B GLY 540 ? B GLY 540 
166 1 Y 1 B LEU 541 ? B LEU 541 
167 1 Y 1 B TRP 542 ? B TRP 542 
168 1 Y 1 B SER 543 ? B SER 543 
169 1 Y 1 B HIS 544 ? B HIS 544 
170 1 Y 1 B PRO 545 ? B PRO 545 
171 1 Y 1 B GLN 546 ? B GLN 546 
172 1 Y 1 B PHE 547 ? B PHE 547 
173 1 Y 1 B GLU 548 ? B GLU 548 
174 1 Y 1 B LYS 549 ? B LYS 549 
175 1 Y 1 B GLY 550 ? B GLY 550 
176 1 Y 1 B GLY 551 ? B GLY 551 
177 1 Y 1 B GLY 552 ? B GLY 552 
178 1 Y 1 B SER 553 ? B SER 553 
179 1 Y 1 B GLY 554 ? B GLY 554 
180 1 Y 1 B GLY 555 ? B GLY 555 
181 1 Y 1 B GLY 556 ? B GLY 556 
182 1 Y 1 B SER 557 ? B SER 557 
183 1 Y 1 B GLY 558 ? B GLY 558 
184 1 Y 1 B GLY 559 ? B GLY 559 
185 1 Y 1 B SER 560 ? B SER 560 
186 1 Y 1 B ALA 561 ? B ALA 561 
187 1 Y 1 B TRP 562 ? B TRP 562 
188 1 Y 1 B SER 563 ? B SER 563 
189 1 Y 1 B HIS 564 ? B HIS 564 
190 1 Y 1 B PRO 565 ? B PRO 565 
191 1 Y 1 B GLN 566 ? B GLN 566 
192 1 Y 1 B PHE 567 ? B PHE 567 
193 1 Y 1 B GLU 568 ? B GLU 568 
194 1 Y 1 B LYS 569 ? B LYS 569 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
Y86 C4   C N N 388 
Y86 C5   C N N 389 
Y86 C6   C N N 390 
Y86 C7   C N N 391 
Y86 C8   C N N 392 
Y86 C10  C N N 393 
Y86 C13  C N N 394 
Y86 C15  C N N 395 
Y86 C17  C N N 396 
Y86 C20  C N R 397 
Y86 C21  C N N 398 
Y86 C22  C N N 399 
Y86 C24  C N N 400 
Y86 C26  C N N 401 
Y86 C28  C N N 402 
Y86 C1   C N N 403 
Y86 C11  C N N 404 
Y86 C12  C N N 405 
Y86 C14  C N N 406 
Y86 C16  C N N 407 
Y86 C18  C N N 408 
Y86 C19  C N N 409 
Y86 C2   C N N 410 
Y86 C23  C N N 411 
Y86 C25  C N N 412 
Y86 C27  C N N 413 
Y86 C29  C N N 414 
Y86 C3   C N N 415 
Y86 C30  C N N 416 
Y86 C31  C N N 417 
Y86 C32  C N N 418 
Y86 C33  C N N 419 
Y86 C34  C N N 420 
Y86 C35  C N N 421 
Y86 C36  C N N 422 
Y86 C37  C N N 423 
Y86 C38  C N N 424 
Y86 C39  C N N 425 
Y86 C40  C N N 426 
Y86 C9   C N N 427 
Y86 O1   O N N 428 
Y86 O2   O N N 429 
Y86 O3   O N N 430 
Y86 O4   O N N 431 
Y86 O5   O N N 432 
Y86 O6   O N N 433 
Y86 O7   O N N 434 
Y86 O8   O N N 435 
Y86 P1   P N N 436 
Y86 H7   H N N 437 
Y86 H8   H N N 438 
Y86 H9   H N N 439 
Y86 H10  H N N 440 
Y86 H11  H N N 441 
Y86 H12  H N N 442 
Y86 H13  H N N 443 
Y86 H15  H N N 444 
Y86 H20  H N N 445 
Y86 H21  H N N 446 
Y86 H25  H N N 447 
Y86 H24  H N N 448 
Y86 H28  H N N 449 
Y86 H29  H N N 450 
Y86 H32  H N N 451 
Y86 H34  H N N 452 
Y86 H33  H N N 453 
Y86 H37  H N N 454 
Y86 H38  H N N 455 
Y86 H42  H N N 456 
Y86 H41  H N N 457 
Y86 H45  H N N 458 
Y86 H46  H N N 459 
Y86 H1   H N N 460 
Y86 H3   H N N 461 
Y86 H2   H N N 462 
Y86 H17  H N N 463 
Y86 H16  H N N 464 
Y86 H19  H N N 465 
Y86 H18  H N N 466 
Y86 H23  H N N 467 
Y86 H22  H N N 468 
Y86 H26  H N N 469 
Y86 H27  H N N 470 
Y86 H31  H N N 471 
Y86 H30  H N N 472 
Y86 H5   H N N 473 
Y86 H4   H N N 474 
Y86 H36  H N N 475 
Y86 H35  H N N 476 
Y86 H40  H N N 477 
Y86 H39  H N N 478 
Y86 H44  H N N 479 
Y86 H43  H N N 480 
Y86 H48  H N N 481 
Y86 H47  H N N 482 
Y86 H6   H N N 483 
Y86 H50  H N N 484 
Y86 H49  H N N 485 
Y86 H51  H N N 486 
Y86 H52  H N N 487 
Y86 H53  H N N 488 
Y86 H54  H N N 489 
Y86 H56  H N N 490 
Y86 H55  H N N 491 
Y86 H57  H N N 492 
Y86 H58  H N N 493 
Y86 H60  H N N 494 
Y86 H59  H N N 495 
Y86 H62  H N N 496 
Y86 H61  H N N 497 
Y86 H63  H N N 498 
Y86 H64  H N N 499 
Y86 H66  H N N 500 
Y86 H65  H N N 501 
Y86 H69  H N N 502 
Y86 H68  H N N 503 
Y86 H67  H N N 504 
Y86 H70  H N N 505 
Y86 H71  H N N 506 
Y86 H14  H N N 507 
Y86 H72  H N N 508 
Y86 H73  H N N 509 
Y8F C1   C N S 510 
Y8F C2   C N N 511 
Y8F C3   C N N 512 
Y8F C4   C N N 513 
Y8F C5   C N N 514 
Y8F C6   C N N 515 
Y8F P1   P N N 516 
Y8F O1   O N N 517 
Y8F O2   O N N 518 
Y8F O3   O N N 519 
Y8F O4   O N N 520 
Y8F O5   O N N 521 
Y8F O6   O N N 522 
Y8F O7   O N N 523 
Y8F O8   O N N 524 
Y8F C10  C N N 525 
Y8F C11  C N N 526 
Y8F C12  C N N 527 
Y8F C13  C N N 528 
Y8F C14  C N N 529 
Y8F C15  C N N 530 
Y8F C16  C N N 531 
Y8F C17  C N N 532 
Y8F C18  C N N 533 
Y8F C19  C N N 534 
Y8F C20  C N N 535 
Y8F C21  C N N 536 
Y8F C22  C N N 537 
Y8F C23  C N N 538 
Y8F C24  C N N 539 
Y8F C25  C N N 540 
Y8F C26  C N N 541 
Y8F C27  C N N 542 
Y8F C28  C N N 543 
Y8F C7   C N N 544 
Y8F C8   C N N 545 
Y8F C9   C N N 546 
Y8F H1   H N N 547 
Y8F H2   H N N 548 
Y8F H3   H N N 549 
Y8F H4   H N N 550 
Y8F H5   H N N 551 
Y8F H6   H N N 552 
Y8F H7   H N N 553 
Y8F H8   H N N 554 
Y8F H9   H N N 555 
Y8F H10  H N N 556 
Y8F H11  H N N 557 
Y8F H12  H N N 558 
Y8F H13  H N N 559 
Y8F H14  H N N 560 
Y8F H15  H N N 561 
Y8F H16  H N N 562 
Y8F H17  H N N 563 
Y8F H18  H N N 564 
Y8F H19  H N N 565 
Y8F H20  H N N 566 
Y8F H21  H N N 567 
Y8F H22  H N N 568 
Y8F H23  H N N 569 
Y8F H24  H N N 570 
Y8F H25  H N N 571 
Y8F H26  H N N 572 
Y8F H27  H N N 573 
Y8F H28  H N N 574 
Y8F H29  H N N 575 
Y8F H30  H N N 576 
Y8F H31  H N N 577 
Y8F H32  H N N 578 
Y8F H33  H N N 579 
Y8F H34  H N N 580 
Y8F H35  H N N 581 
Y8F H36  H N N 582 
Y8F H37  H N N 583 
Y8F H38  H N N 584 
Y8F H39  H N N 585 
Y8F H40  H N N 586 
Y8F H41  H N N 587 
Y8F H42  H N N 588 
Y8F H43  H N N 589 
Y8F H44  H N N 590 
Y8F H45  H N N 591 
Y8F H46  H N N 592 
Y8F H47  H N N 593 
Y8F H48  H N N 594 
Y8F H49  H N N 595 
Y8F H50  H N N 596 
Y8F H51  H N N 597 
Y8F H52  H N N 598 
Y8F H53  H N N 599 
Y8F H54  H N N 600 
Y8F H55  H N N 601 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
Y86 C1  C2   sing N N 374 
Y86 C2  C3   sing N N 375 
Y86 C3  C4   doub N Z 376 
Y86 C4  C5   sing N N 377 
Y86 C5  C6   sing N N 378 
Y86 C6  C7   doub N Z 379 
Y86 C7  C8   sing N N 380 
Y86 C8  C9   sing N N 381 
Y86 C9  C10  doub N Z 382 
Y86 C10 C11  sing N N 383 
Y86 C11 C12  sing N N 384 
Y86 C12 C13  sing N N 385 
Y86 C13 C14  sing N N 386 
Y86 C14 C15  sing N N 387 
Y86 C15 C16  sing N N 388 
Y86 C16 C17  sing N N 389 
Y86 C17 C18  sing N N 390 
Y86 C18 O1   sing N N 391 
Y86 O1  C19  sing N N 392 
Y86 C19 C20  sing N N 393 
Y86 C20 O2   sing N N 394 
Y86 O2  C21  sing N N 395 
Y86 C21 C22  sing N N 396 
Y86 C22 C23  sing N N 397 
Y86 C23 C24  sing N N 398 
Y86 C24 C25  sing N N 399 
Y86 C25 C26  sing N N 400 
Y86 C26 C27  sing N N 401 
Y86 C27 C28  sing N N 402 
Y86 C28 C29  sing N N 403 
Y86 C29 C30  sing N N 404 
Y86 C30 C31  sing N N 405 
Y86 C31 C32  sing N N 406 
Y86 C32 C33  sing N N 407 
Y86 C33 C34  sing N N 408 
Y86 C34 C35  sing N N 409 
Y86 C35 C36  sing N N 410 
Y86 C36 C37  sing N N 411 
Y86 C37 C38  sing N N 412 
Y86 C38 C39  sing N N 413 
Y86 C21 O3   doub N N 414 
Y86 C20 C40  sing N N 415 
Y86 C40 O4   sing N N 416 
Y86 O4  P1   sing N N 417 
Y86 P1  O5   sing N N 418 
Y86 P1  O6   sing N N 419 
Y86 P1  O7   doub N N 420 
Y86 C18 O8   doub N N 421 
Y86 C4  H7   sing N N 422 
Y86 C5  H8   sing N N 423 
Y86 C5  H9   sing N N 424 
Y86 C6  H10  sing N N 425 
Y86 C7  H11  sing N N 426 
Y86 C8  H12  sing N N 427 
Y86 C8  H13  sing N N 428 
Y86 C10 H15  sing N N 429 
Y86 C13 H20  sing N N 430 
Y86 C13 H21  sing N N 431 
Y86 C15 H25  sing N N 432 
Y86 C15 H24  sing N N 433 
Y86 C17 H28  sing N N 434 
Y86 C17 H29  sing N N 435 
Y86 C20 H32  sing N N 436 
Y86 C22 H34  sing N N 437 
Y86 C22 H33  sing N N 438 
Y86 C24 H37  sing N N 439 
Y86 C24 H38  sing N N 440 
Y86 C26 H42  sing N N 441 
Y86 C26 H41  sing N N 442 
Y86 C28 H45  sing N N 443 
Y86 C28 H46  sing N N 444 
Y86 C1  H1   sing N N 445 
Y86 C1  H3   sing N N 446 
Y86 C1  H2   sing N N 447 
Y86 C11 H17  sing N N 448 
Y86 C11 H16  sing N N 449 
Y86 C12 H19  sing N N 450 
Y86 C12 H18  sing N N 451 
Y86 C14 H23  sing N N 452 
Y86 C14 H22  sing N N 453 
Y86 C16 H26  sing N N 454 
Y86 C16 H27  sing N N 455 
Y86 C19 H31  sing N N 456 
Y86 C19 H30  sing N N 457 
Y86 C2  H5   sing N N 458 
Y86 C2  H4   sing N N 459 
Y86 C23 H36  sing N N 460 
Y86 C23 H35  sing N N 461 
Y86 C25 H40  sing N N 462 
Y86 C25 H39  sing N N 463 
Y86 C27 H44  sing N N 464 
Y86 C27 H43  sing N N 465 
Y86 C29 H48  sing N N 466 
Y86 C29 H47  sing N N 467 
Y86 C3  H6   sing N N 468 
Y86 C30 H50  sing N N 469 
Y86 C30 H49  sing N N 470 
Y86 C31 H51  sing N N 471 
Y86 C31 H52  sing N N 472 
Y86 C32 H53  sing N N 473 
Y86 C32 H54  sing N N 474 
Y86 C33 H56  sing N N 475 
Y86 C33 H55  sing N N 476 
Y86 C34 H57  sing N N 477 
Y86 C34 H58  sing N N 478 
Y86 C35 H60  sing N N 479 
Y86 C35 H59  sing N N 480 
Y86 C36 H62  sing N N 481 
Y86 C36 H61  sing N N 482 
Y86 C37 H63  sing N N 483 
Y86 C37 H64  sing N N 484 
Y86 C38 H66  sing N N 485 
Y86 C38 H65  sing N N 486 
Y86 C39 H69  sing N N 487 
Y86 C39 H68  sing N N 488 
Y86 C39 H67  sing N N 489 
Y86 C40 H70  sing N N 490 
Y86 C40 H71  sing N N 491 
Y86 C9  H14  sing N N 492 
Y86 O5  H72  sing N N 493 
Y86 O6  H73  sing N N 494 
Y8F C28 C27  sing N N 495 
Y8F C27 C26  sing N N 496 
Y8F C26 C25  sing N N 497 
Y8F C25 C24  sing N N 498 
Y8F C23 C24  sing N N 499 
Y8F C23 C22  sing N N 500 
Y8F C22 C21  sing N N 501 
Y8F C21 C20  sing N N 502 
Y8F C20 C19  sing N N 503 
Y8F C19 C18  sing N N 504 
Y8F C18 C17  sing N N 505 
Y8F C17 O8   doub N N 506 
Y8F C17 O7   sing N N 507 
Y8F O3  P1   doub N N 508 
Y8F O7  C16  sing N N 509 
Y8F C16 C1   sing N N 510 
Y8F P1  O2   sing N N 511 
Y8F P1  O1   sing N N 512 
Y8F P1  O4   sing N N 513 
Y8F C2  O1   sing N N 514 
Y8F C2  C1   sing N N 515 
Y8F C1  O5   sing N N 516 
Y8F O5  C3   sing N N 517 
Y8F O6  C3   doub N N 518 
Y8F C3  C4   sing N N 519 
Y8F C4  C5   sing N N 520 
Y8F C5  C6   sing N N 521 
Y8F C6  C7   sing N N 522 
Y8F C7  C8   sing N N 523 
Y8F C8  C9   sing N N 524 
Y8F C9  C10  sing N N 525 
Y8F C10 C11  sing N N 526 
Y8F C11 C12  sing N N 527 
Y8F C12 C13  sing N N 528 
Y8F C13 C14  sing N N 529 
Y8F C14 C15  sing N N 530 
Y8F C1  H1   sing N N 531 
Y8F C2  H2   sing N N 532 
Y8F C2  H3   sing N N 533 
Y8F C4  H4   sing N N 534 
Y8F C4  H5   sing N N 535 
Y8F C5  H6   sing N N 536 
Y8F C5  H7   sing N N 537 
Y8F C6  H8   sing N N 538 
Y8F C6  H9   sing N N 539 
Y8F O2  H10  sing N N 540 
Y8F O4  H11  sing N N 541 
Y8F C10 H12  sing N N 542 
Y8F C10 H13  sing N N 543 
Y8F C11 H14  sing N N 544 
Y8F C11 H15  sing N N 545 
Y8F C12 H16  sing N N 546 
Y8F C12 H17  sing N N 547 
Y8F C13 H18  sing N N 548 
Y8F C13 H19  sing N N 549 
Y8F C14 H20  sing N N 550 
Y8F C14 H21  sing N N 551 
Y8F C15 H22  sing N N 552 
Y8F C15 H23  sing N N 553 
Y8F C15 H24  sing N N 554 
Y8F C16 H25  sing N N 555 
Y8F C16 H26  sing N N 556 
Y8F C18 H27  sing N N 557 
Y8F C18 H28  sing N N 558 
Y8F C19 H29  sing N N 559 
Y8F C19 H30  sing N N 560 
Y8F C20 H31  sing N N 561 
Y8F C20 H32  sing N N 562 
Y8F C21 H33  sing N N 563 
Y8F C21 H34  sing N N 564 
Y8F C22 H35  sing N N 565 
Y8F C22 H36  sing N N 566 
Y8F C23 H37  sing N N 567 
Y8F C23 H38  sing N N 568 
Y8F C24 H39  sing N N 569 
Y8F C24 H40  sing N N 570 
Y8F C25 H41  sing N N 571 
Y8F C25 H42  sing N N 572 
Y8F C26 H43  sing N N 573 
Y8F C26 H44  sing N N 574 
Y8F C27 H45  sing N N 575 
Y8F C27 H46  sing N N 576 
Y8F C28 H47  sing N N 577 
Y8F C28 H48  sing N N 578 
Y8F C28 H49  sing N N 579 
Y8F C7  H50  sing N N 580 
Y8F C7  H51  sing N N 581 
Y8F C8  H52  sing N N 582 
Y8F C8  H53  sing N N 583 
Y8F C9  H54  sing N N 584 
Y8F C9  H55  sing N N 585 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-11-22 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8X6X 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-27 
_em_admin.title              'Structure of the multidrug efflux pump EfpA from M. tuberculosis complexed with lipids' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          1773 
_em_entity_assembly_naturalsource.organism             'Mycobacterium tuberculosis' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          4896 
_em_entity_assembly_recombinant.organism             'Schizosaccharomyces pombe' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Science Foundation (NSF, China)' China 82272379        1 
'Other government'                         ?     2019A1515110675 2 
# 
_space_group.crystal_system   triclinic 
_space_group.name_H-M_alt     'P 1' 
_space_group.IT_number        1 
_space_group.name_Hall        'P 1' 
_space_group.id               1 
# 
_atom_sites.entry_id                    8X6X 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . SER A 1 48  ? 146.751 184.200 214.839 1.00 84.76  ? 48  SER A N   1 
ATOM   2    C CA  . SER A 1 48  ? 147.071 185.273 215.773 1.00 84.76  ? 48  SER A CA  1 
ATOM   3    C C   . SER A 1 48  ? 148.535 185.214 216.187 1.00 84.76  ? 48  SER A C   1 
ATOM   4    O O   . SER A 1 48  ? 149.362 184.632 215.488 1.00 84.76  ? 48  SER A O   1 
ATOM   5    C CB  . SER A 1 48  ? 146.174 185.197 217.008 1.00 84.76  ? 48  SER A CB  1 
ATOM   6    O OG  . SER A 1 48  ? 146.585 186.129 217.993 1.00 84.76  ? 48  SER A OG  1 
ATOM   7    N N   . ARG A 1 49  ? 148.851 185.827 217.329 1.00 84.11  ? 49  ARG A N   1 
ATOM   8    C CA  . ARG A 1 49  ? 150.215 185.789 217.840 1.00 84.11  ? 49  ARG A CA  1 
ATOM   9    C C   . ARG A 1 49  ? 150.567 184.436 218.443 1.00 84.11  ? 49  ARG A C   1 
ATOM   10   O O   . ARG A 1 49  ? 151.753 184.102 218.534 1.00 84.11  ? 49  ARG A O   1 
ATOM   11   C CB  . ARG A 1 49  ? 150.421 186.892 218.879 1.00 84.11  ? 49  ARG A CB  1 
ATOM   12   C CG  . ARG A 1 49  ? 151.877 187.253 219.126 1.00 84.11  ? 49  ARG A CG  1 
ATOM   13   C CD  . ARG A 1 49  ? 152.474 187.998 217.942 1.00 84.11  ? 49  ARG A CD  1 
ATOM   14   N NE  . ARG A 1 49  ? 152.140 189.417 217.962 1.00 84.11  ? 49  ARG A NE  1 
ATOM   15   C CZ  . ARG A 1 49  ? 152.553 190.297 217.059 1.00 84.11  ? 49  ARG A CZ  1 
ATOM   16   N NH1 . ARG A 1 49  ? 153.325 189.938 216.047 1.00 84.11  ? 49  ARG A NH1 1 
ATOM   17   N NH2 . ARG A 1 49  ? 152.182 191.569 217.176 1.00 84.11  ? 49  ARG A NH2 1 
ATOM   18   N N   . SER A 1 50  ? 149.567 183.654 218.857 1.00 78.26  ? 50  SER A N   1 
ATOM   19   C CA  . SER A 1 50  ? 149.842 182.341 219.430 1.00 78.26  ? 50  SER A CA  1 
ATOM   20   C C   . SER A 1 50  ? 150.510 181.423 218.414 1.00 78.26  ? 50  SER A C   1 
ATOM   21   O O   . SER A 1 50  ? 151.468 180.714 218.744 1.00 78.26  ? 50  SER A O   1 
ATOM   22   C CB  . SER A 1 50  ? 148.548 181.717 219.949 1.00 78.26  ? 50  SER A CB  1 
ATOM   23   O OG  . SER A 1 50  ? 147.716 181.311 218.876 1.00 78.26  ? 50  SER A OG  1 
ATOM   24   N N   . PHE A 1 51  ? 150.019 181.428 217.173 1.00 71.26  ? 51  PHE A N   1 
ATOM   25   C CA  . PHE A 1 51  ? 150.619 180.606 216.125 1.00 71.26  ? 51  PHE A CA  1 
ATOM   26   C C   . PHE A 1 51  ? 152.068 181.003 215.877 1.00 71.26  ? 51  PHE A C   1 
ATOM   27   O O   . PHE A 1 51  ? 152.950 180.139 215.760 1.00 71.26  ? 51  PHE A O   1 
ATOM   28   C CB  . PHE A 1 51  ? 149.790 180.734 214.845 1.00 71.26  ? 51  PHE A CB  1 
ATOM   29   C CG  . PHE A 1 51  ? 150.338 179.967 213.677 1.00 71.26  ? 51  PHE A CG  1 
ATOM   30   C CD1 . PHE A 1 51  ? 149.999 178.642 213.483 1.00 71.26  ? 51  PHE A CD1 1 
ATOM   31   C CD2 . PHE A 1 51  ? 151.172 180.579 212.758 1.00 71.26  ? 51  PHE A CD2 1 
ATOM   32   C CE1 . PHE A 1 51  ? 150.493 177.938 212.406 1.00 71.26  ? 51  PHE A CE1 1 
ATOM   33   C CE2 . PHE A 1 51  ? 151.670 179.879 211.681 1.00 71.26  ? 51  PHE A CE2 1 
ATOM   34   C CZ  . PHE A 1 51  ? 151.330 178.557 211.504 1.00 71.26  ? 51  PHE A CZ  1 
ATOM   35   N N   . ILE A 1 52  ? 152.333 182.309 215.801 1.00 71.42  ? 52  ILE A N   1 
ATOM   36   C CA  . ILE A 1 52  ? 153.685 182.792 215.541 1.00 71.42  ? 52  ILE A CA  1 
ATOM   37   C C   . ILE A 1 52  ? 154.615 182.393 216.680 1.00 71.42  ? 52  ILE A C   1 
ATOM   38   O O   . ILE A 1 52  ? 155.734 181.911 216.457 1.00 71.42  ? 52  ILE A O   1 
ATOM   39   C CB  . ILE A 1 52  ? 153.671 184.315 215.330 1.00 71.42  ? 52  ILE A CB  1 
ATOM   40   C CG1 . ILE A 1 52  ? 152.653 184.688 214.252 1.00 71.42  ? 52  ILE A CG1 1 
ATOM   41   C CG2 . ILE A 1 52  ? 155.047 184.816 214.941 1.00 71.42  ? 52  ILE A CG2 1 
ATOM   42   C CD1 . ILE A 1 52  ? 152.928 184.061 212.909 1.00 71.42  ? 52  ILE A CD1 1 
ATOM   43   N N   . ALA A 1 53  ? 154.161 182.582 217.920 1.00 70.41  ? 53  ALA A N   1 
ATOM   44   C CA  . ALA A 1 53  ? 154.978 182.209 219.069 1.00 70.41  ? 53  ALA A CA  1 
ATOM   45   C C   . ALA A 1 53  ? 155.260 180.714 219.080 1.00 70.41  ? 53  ALA A C   1 
ATOM   46   O O   . ALA A 1 53  ? 156.386 180.291 219.365 1.00 70.41  ? 53  ALA A O   1 
ATOM   47   C CB  . ALA A 1 53  ? 154.291 182.638 220.364 1.00 70.41  ? 53  ALA A CB  1 
ATOM   48   N N   . ALA A 1 54  ? 154.253 179.898 218.758 1.00 68.87  ? 54  ALA A N   1 
ATOM   49   C CA  . ALA A 1 54  ? 154.440 178.451 218.757 1.00 68.87  ? 54  ALA A CA  1 
ATOM   50   C C   . ALA A 1 54  ? 155.466 178.024 217.715 1.00 68.87  ? 54  ALA A C   1 
ATOM   51   O O   . ALA A 1 54  ? 156.376 177.238 218.010 1.00 68.87  ? 54  ALA A O   1 
ATOM   52   C CB  . ALA A 1 54  ? 153.102 177.754 218.514 1.00 68.87  ? 54  ALA A CB  1 
ATOM   53   N N   . VAL A 1 55  ? 155.344 178.538 216.488 1.00 64.73  ? 55  VAL A N   1 
ATOM   54   C CA  . VAL A 1 55  ? 156.266 178.108 215.439 1.00 64.73  ? 55  VAL A CA  1 
ATOM   55   C C   . VAL A 1 55  ? 157.682 178.595 215.734 1.00 64.73  ? 55  VAL A C   1 
ATOM   56   O O   . VAL A 1 55  ? 158.662 177.872 215.497 1.00 64.73  ? 55  VAL A O   1 
ATOM   57   C CB  . VAL A 1 55  ? 155.772 178.559 214.051 1.00 64.73  ? 55  VAL A CB  1 
ATOM   58   C CG1 . VAL A 1 55  ? 154.452 177.893 213.723 1.00 64.73  ? 55  VAL A CG1 1 
ATOM   59   C CG2 . VAL A 1 55  ? 155.637 180.062 213.970 1.00 64.73  ? 55  VAL A CG2 1 
ATOM   60   N N   . ILE A 1 56  ? 157.819 179.809 216.279 1.00 65.20  ? 56  ILE A N   1 
ATOM   61   C CA  . ILE A 1 56  ? 159.145 180.304 216.638 1.00 65.20  ? 56  ILE A CA  1 
ATOM   62   C C   . ILE A 1 56  ? 159.756 179.444 217.737 1.00 65.20  ? 56  ILE A C   1 
ATOM   63   O O   . ILE A 1 56  ? 160.938 179.076 217.676 1.00 65.20  ? 56  ILE A O   1 
ATOM   64   C CB  . ILE A 1 56  ? 159.067 181.783 217.054 1.00 65.20  ? 56  ILE A CB  1 
ATOM   65   C CG1 . ILE A 1 56  ? 158.782 182.662 215.838 1.00 65.20  ? 56  ILE A CG1 1 
ATOM   66   C CG2 . ILE A 1 56  ? 160.355 182.219 217.726 1.00 65.20  ? 56  ILE A CG2 1 
ATOM   67   C CD1 . ILE A 1 56  ? 158.392 184.072 216.194 1.00 65.20  ? 56  ILE A CD1 1 
ATOM   68   N N   . ALA A 1 57  ? 158.961 179.100 218.754 1.00 64.28  ? 57  ALA A N   1 
ATOM   69   C CA  . ALA A 1 57  ? 159.472 178.284 219.848 1.00 64.28  ? 57  ALA A CA  1 
ATOM   70   C C   . ALA A 1 57  ? 159.905 176.913 219.357 1.00 64.28  ? 57  ALA A C   1 
ATOM   71   O O   . ALA A 1 57  ? 160.903 176.362 219.833 1.00 64.28  ? 57  ALA A O   1 
ATOM   72   C CB  . ALA A 1 57  ? 158.415 178.151 220.942 1.00 64.28  ? 57  ALA A CB  1 
ATOM   73   N N   . ILE A 1 58  ? 159.165 176.341 218.407 1.00 61.04  ? 58  ILE A N   1 
ATOM   74   C CA  . ILE A 1 58  ? 159.529 175.020 217.904 1.00 61.04  ? 58  ILE A CA  1 
ATOM   75   C C   . ILE A 1 58  ? 160.805 175.087 217.067 1.00 61.04  ? 58  ILE A C   1 
ATOM   76   O O   . ILE A 1 58  ? 161.667 174.206 217.164 1.00 61.04  ? 58  ILE A O   1 
ATOM   77   C CB  . ILE A 1 58  ? 158.361 174.401 217.121 1.00 61.04  ? 58  ILE A CB  1 
ATOM   78   C CG1 . ILE A 1 58  ? 157.159 174.199 218.040 1.00 61.04  ? 58  ILE A CG1 1 
ATOM   79   C CG2 . ILE A 1 58  ? 158.770 173.072 216.555 1.00 61.04  ? 58  ILE A CG2 1 
ATOM   80   C CD1 . ILE A 1 58  ? 155.912 173.760 217.319 1.00 61.04  ? 58  ILE A CD1 1 
ATOM   81   N N   . GLY A 1 59  ? 160.956 176.123 216.237 1.00 61.40  ? 59  GLY A N   1 
ATOM   82   C CA  . GLY A 1 59  ? 162.177 176.231 215.446 1.00 61.40  ? 59  GLY A CA  1 
ATOM   83   C C   . GLY A 1 59  ? 163.395 176.750 216.191 1.00 61.40  ? 59  GLY A C   1 
ATOM   84   O O   . GLY A 1 59  ? 164.505 176.758 215.632 1.00 61.40  ? 59  GLY A O   1 
ATOM   85   N N   . GLY A 1 60  ? 163.202 177.194 217.435 1.00 60.90  ? 60  GLY A N   1 
ATOM   86   C CA  . GLY A 1 60  ? 164.312 177.738 218.199 1.00 60.90  ? 60  GLY A CA  1 
ATOM   87   C C   . GLY A 1 60  ? 165.464 176.769 218.385 1.00 60.90  ? 60  GLY A C   1 
ATOM   88   O O   . GLY A 1 60  ? 166.628 177.169 218.361 1.00 60.90  ? 60  GLY A O   1 
ATOM   89   N N   . MET A 1 61  ? 165.161 175.487 218.598 1.00 59.56  ? 61  MET A N   1 
ATOM   90   C CA  . MET A 1 61  ? 166.234 174.524 218.834 1.00 59.56  ? 61  MET A CA  1 
ATOM   91   C C   . MET A 1 61  ? 167.098 174.351 217.591 1.00 59.56  ? 61  MET A C   1 
ATOM   92   O O   . MET A 1 61  ? 168.329 174.282 217.687 1.00 59.56  ? 61  MET A O   1 
ATOM   93   C CB  . MET A 1 61  ? 165.652 173.183 219.273 1.00 59.56  ? 61  MET A CB  1 
ATOM   94   C CG  . MET A 1 61  ? 166.684 172.131 219.668 1.00 59.56  ? 61  MET A CG  1 
ATOM   95   S SD  . MET A 1 61  ? 167.868 172.710 220.906 1.00 59.56  ? 61  MET A SD  1 
ATOM   96   C CE  . MET A 1 61  ? 169.419 172.578 220.031 1.00 59.56  ? 61  MET A CE  1 
ATOM   97   N N   . GLN A 1 62  ? 166.471 174.282 216.415 1.00 59.81  ? 62  GLN A N   1 
ATOM   98   C CA  . GLN A 1 62  ? 167.233 174.217 215.172 1.00 59.81  ? 62  GLN A CA  1 
ATOM   99   C C   . GLN A 1 62  ? 168.099 175.454 215.001 1.00 59.81  ? 62  GLN A C   1 
ATOM   100  O O   . GLN A 1 62  ? 169.279 175.354 214.628 1.00 59.81  ? 62  GLN A O   1 
ATOM   101  C CB  . GLN A 1 62  ? 166.287 174.067 213.982 1.00 59.81  ? 62  GLN A CB  1 
ATOM   102  C CG  . GLN A 1 62  ? 165.670 172.693 213.847 1.00 59.81  ? 62  GLN A CG  1 
ATOM   103  C CD  . GLN A 1 62  ? 166.603 171.702 213.193 1.00 59.81  ? 62  GLN A CD  1 
ATOM   104  O OE1 . GLN A 1 62  ? 166.716 171.653 211.970 1.00 59.81  ? 62  GLN A OE1 1 
ATOM   105  N NE2 . GLN A 1 62  ? 167.281 170.902 214.007 1.00 59.81  ? 62  GLN A NE2 1 
ATOM   106  N N   . LEU A 1 63  ? 167.533 176.632 215.280 1.00 60.65  ? 63  LEU A N   1 
ATOM   107  C CA  . LEU A 1 63  ? 168.313 177.861 215.164 1.00 60.65  ? 63  LEU A CA  1 
ATOM   108  C C   . LEU A 1 63  ? 169.531 177.822 216.081 1.00 60.65  ? 63  LEU A C   1 
ATOM   109  O O   . LEU A 1 63  ? 170.655 178.116 215.654 1.00 60.65  ? 63  LEU A O   1 
ATOM   110  C CB  . LEU A 1 63  ? 167.427 179.071 215.469 1.00 60.65  ? 63  LEU A CB  1 
ATOM   111  C CG  . LEU A 1 63  ? 167.971 180.484 215.233 1.00 60.65  ? 63  LEU A CG  1 
ATOM   112  C CD1 . LEU A 1 63  ? 166.827 181.427 214.934 1.00 60.65  ? 63  LEU A CD1 1 
ATOM   113  C CD2 . LEU A 1 63  ? 168.748 180.998 216.431 1.00 60.65  ? 63  LEU A CD2 1 
ATOM   114  N N   . LEU A 1 64  ? 169.328 177.433 217.344 1.00 60.09  ? 64  LEU A N   1 
ATOM   115  C CA  . LEU A 1 64  ? 170.429 177.393 218.303 1.00 60.09  ? 64  LEU A CA  1 
ATOM   116  C C   . LEU A 1 64  ? 171.504 176.409 217.874 1.00 60.09  ? 64  LEU A C   1 
ATOM   117  O O   . LEU A 1 64  ? 172.698 176.729 217.901 1.00 60.09  ? 64  LEU A O   1 
ATOM   118  C CB  . LEU A 1 64  ? 169.915 177.023 219.692 1.00 60.09  ? 64  LEU A CB  1 
ATOM   119  C CG  . LEU A 1 64  ? 169.656 178.157 220.676 1.00 60.09  ? 64  LEU A CG  1 
ATOM   120  C CD1 . LEU A 1 64  ? 168.431 178.927 220.263 1.00 60.09  ? 64  LEU A CD1 1 
ATOM   121  C CD2 . LEU A 1 64  ? 169.503 177.609 222.080 1.00 60.09  ? 64  LEU A CD2 1 
ATOM   122  N N   . ALA A 1 65  ? 171.101 175.199 217.484 1.00 60.20  ? 65  ALA A N   1 
ATOM   123  C CA  . ALA A 1 65  ? 172.078 174.181 217.119 1.00 60.20  ? 65  ALA A CA  1 
ATOM   124  C C   . ALA A 1 65  ? 172.921 174.632 215.936 1.00 60.20  ? 65  ALA A C   1 
ATOM   125  O O   . ALA A 1 65  ? 174.157 174.557 215.972 1.00 60.20  ? 65  ALA A O   1 
ATOM   126  C CB  . ALA A 1 65  ? 171.372 172.863 216.806 1.00 60.20  ? 65  ALA A CB  1 
ATOM   127  N N   . THR A 1 66  ? 172.270 175.130 214.880 1.00 60.57  ? 66  THR A N   1 
ATOM   128  C CA  . THR A 1 66  ? 173.020 175.507 213.688 1.00 60.57  ? 66  THR A CA  1 
ATOM   129  C C   . THR A 1 66  ? 173.920 176.710 213.956 1.00 60.57  ? 66  THR A C   1 
ATOM   130  O O   . THR A 1 66  ? 175.083 176.735 213.523 1.00 60.57  ? 66  THR A O   1 
ATOM   131  C CB  . THR A 1 66  ? 172.059 175.791 212.539 1.00 60.57  ? 66  THR A CB  1 
ATOM   132  O OG1 . THR A 1 66  ? 171.117 174.718 212.435 1.00 60.57  ? 66  THR A OG1 1 
ATOM   133  C CG2 . THR A 1 66  ? 172.823 175.869 211.247 1.00 60.57  ? 66  THR A CG2 1 
ATOM   134  N N   . MET A 1 67  ? 173.408 177.710 214.680 1.00 64.05  ? 67  MET A N   1 
ATOM   135  C CA  . MET A 1 67  ? 174.206 178.892 214.983 1.00 64.05  ? 67  MET A CA  1 
ATOM   136  C C   . MET A 1 67  ? 175.423 178.539 215.828 1.00 64.05  ? 67  MET A C   1 
ATOM   137  O O   . MET A 1 67  ? 176.533 179.019 215.568 1.00 64.05  ? 67  MET A O   1 
ATOM   138  C CB  . MET A 1 67  ? 173.330 179.935 215.677 1.00 64.05  ? 67  MET A CB  1 
ATOM   139  C CG  . MET A 1 67  ? 174.032 181.232 216.004 1.00 64.05  ? 67  MET A CG  1 
ATOM   140  S SD  . MET A 1 67  ? 172.935 182.425 216.785 1.00 64.05  ? 67  MET A SD  1 
ATOM   141  C CE  . MET A 1 67  ? 172.720 181.693 218.399 1.00 64.05  ? 67  MET A CE  1 
ATOM   142  N N   . ASP A 1 68  ? 175.238 177.690 216.842 1.00 64.96  ? 68  ASP A N   1 
ATOM   143  C CA  . ASP A 1 68  ? 176.365 177.293 217.677 1.00 64.96  ? 68  ASP A CA  1 
ATOM   144  C C   . ASP A 1 68  ? 177.388 176.492 216.887 1.00 64.96  ? 68  ASP A C   1 
ATOM   145  O O   . ASP A 1 68  ? 178.596 176.661 217.082 1.00 64.96  ? 68  ASP A O   1 
ATOM   146  C CB  . ASP A 1 68  ? 175.882 176.494 218.881 1.00 64.96  ? 68  ASP A CB  1 
ATOM   147  C CG  . ASP A 1 68  ? 176.991 176.222 219.872 1.00 64.96  ? 68  ASP A CG  1 
ATOM   148  O OD1 . ASP A 1 68  ? 177.218 177.068 220.762 1.00 64.96  ? 68  ASP A OD1 1 
ATOM   149  O OD2 . ASP A 1 68  ? 177.637 175.159 219.762 1.00 64.96  ? 68  ASP A OD2 1 
ATOM   150  N N   . SER A 1 69  ? 176.931 175.603 216.000 1.00 64.44  ? 69  SER A N   1 
ATOM   151  C CA  . SER A 1 69  ? 177.875 174.854 215.177 1.00 64.44  ? 69  SER A CA  1 
ATOM   152  C C   . SER A 1 69  ? 178.726 175.793 214.332 1.00 64.44  ? 69  SER A C   1 
ATOM   153  O O   . SER A 1 69  ? 179.959 175.677 214.301 1.00 64.44  ? 69  SER A O   1 
ATOM   154  C CB  . SER A 1 69  ? 177.127 173.858 214.292 1.00 64.44  ? 69  SER A CB  1 
ATOM   155  O OG  . SER A 1 69  ? 176.563 172.816 215.067 1.00 64.44  ? 69  SER A OG  1 
ATOM   156  N N   . THR A 1 70  ? 178.082 176.751 213.657 1.00 64.84  ? 70  THR A N   1 
ATOM   157  C CA  . THR A 1 70  ? 178.832 177.683 212.818 1.00 64.84  ? 70  THR A CA  1 
ATOM   158  C C   . THR A 1 70  ? 179.813 178.512 213.643 1.00 64.84  ? 70  THR A C   1 
ATOM   159  O O   . THR A 1 70  ? 180.980 178.675 213.259 1.00 64.84  ? 70  THR A O   1 
ATOM   160  C CB  . THR A 1 70  ? 177.872 178.594 212.057 1.00 64.84  ? 70  THR A CB  1 
ATOM   161  O OG1 . THR A 1 70  ? 176.863 177.801 211.423 1.00 64.84  ? 70  THR A OG1 1 
ATOM   162  C CG2 . THR A 1 70  ? 178.619 179.381 210.999 1.00 64.84  ? 70  THR A CG2 1 
ATOM   163  N N   . VAL A 1 71  ? 179.365 179.027 214.791 1.00 65.09  ? 71  VAL A N   1 
ATOM   164  C CA  . VAL A 1 71  ? 180.230 179.858 215.625 1.00 65.09  ? 71  VAL A CA  1 
ATOM   165  C C   . VAL A 1 71  ? 181.426 179.057 216.124 1.00 65.09  ? 71  VAL A C   1 
ATOM   166  O O   . VAL A 1 71  ? 182.561 179.546 216.126 1.00 65.09  ? 71  VAL A O   1 
ATOM   167  C CB  . VAL A 1 71  ? 179.427 180.464 216.790 1.00 65.09  ? 71  VAL A CB  1 
ATOM   168  C CG1 . VAL A 1 71  ? 180.357 180.961 217.874 1.00 65.09  ? 71  VAL A CG1 1 
ATOM   169  C CG2 . VAL A 1 71  ? 178.552 181.593 216.290 1.00 65.09  ? 71  VAL A CG2 1 
ATOM   170  N N   . ALA A 1 72  ? 181.194 177.814 216.554 1.00 67.97  ? 72  ALA A N   1 
ATOM   171  C CA  . ALA A 1 72  ? 182.293 176.984 217.032 1.00 67.97  ? 72  ALA A CA  1 
ATOM   172  C C   . ALA A 1 72  ? 183.297 176.700 215.923 1.00 67.97  ? 72  ALA A C   1 
ATOM   173  O O   . ALA A 1 72  ? 184.509 176.699 216.163 1.00 67.97  ? 72  ALA A O   1 
ATOM   174  C CB  . ALA A 1 72  ? 181.751 175.680 217.614 1.00 67.97  ? 72  ALA A CB  1 
ATOM   175  N N   . ILE A 1 73  ? 182.814 176.451 214.703 1.00 70.70  ? 73  ILE A N   1 
ATOM   176  C CA  . ILE A 1 73  ? 183.735 176.201 213.595 1.00 70.70  ? 73  ILE A CA  1 
ATOM   177  C C   . ILE A 1 73  ? 184.565 177.442 213.288 1.00 70.70  ? 73  ILE A C   1 
ATOM   178  O O   . ILE A 1 73  ? 185.759 177.344 212.977 1.00 70.70  ? 73  ILE A O   1 
ATOM   179  C CB  . ILE A 1 73  ? 182.972 175.708 212.351 1.00 70.70  ? 73  ILE A CB  1 
ATOM   180  C CG1 . ILE A 1 73  ? 182.214 174.419 212.667 1.00 70.70  ? 73  ILE A CG1 1 
ATOM   181  C CG2 . ILE A 1 73  ? 183.924 175.487 211.190 1.00 70.70  ? 73  ILE A CG2 1 
ATOM   182  C CD1 . ILE A 1 73  ? 183.109 173.279 213.083 1.00 70.70  ? 73  ILE A CD1 1 
ATOM   183  N N   . VAL A 1 74  ? 183.953 178.627 213.365 1.00 71.80  ? 74  VAL A N   1 
ATOM   184  C CA  . VAL A 1 74  ? 184.667 179.847 212.988 1.00 71.80  ? 74  VAL A CA  1 
ATOM   185  C C   . VAL A 1 74  ? 185.842 180.121 213.926 1.00 71.80  ? 74  VAL A C   1 
ATOM   186  O O   . VAL A 1 74  ? 186.935 180.484 213.477 1.00 71.80  ? 74  VAL A O   1 
ATOM   187  C CB  . VAL A 1 74  ? 183.697 181.041 212.930 1.00 71.80  ? 74  VAL A CB  1 
ATOM   188  C CG1 . VAL A 1 74  ? 184.461 182.333 212.723 1.00 71.80  ? 74  VAL A CG1 1 
ATOM   189  C CG2 . VAL A 1 74  ? 182.708 180.854 211.799 1.00 71.80  ? 74  VAL A CG2 1 
ATOM   190  N N   . ALA A 1 75  ? 185.648 179.947 215.235 1.00 76.58  ? 75  ALA A N   1 
ATOM   191  C CA  . ALA A 1 75  ? 186.579 180.458 216.236 1.00 76.58  ? 75  ALA A CA  1 
ATOM   192  C C   . ALA A 1 75  ? 187.554 179.403 216.758 1.00 76.58  ? 75  ALA A C   1 
ATOM   193  O O   . ALA A 1 75  ? 187.989 179.487 217.911 1.00 76.58  ? 75  ALA A O   1 
ATOM   194  C CB  . ALA A 1 75  ? 185.805 181.074 217.400 1.00 76.58  ? 75  ALA A CB  1 
ATOM   195  N N   . LEU A 1 76  ? 187.911 178.413 215.941 1.00 81.77  ? 76  LEU A N   1 
ATOM   196  C CA  . LEU A 1 76  ? 188.870 177.401 216.384 1.00 81.77  ? 76  LEU A CA  1 
ATOM   197  C C   . LEU A 1 76  ? 190.272 177.949 216.639 1.00 81.77  ? 76  LEU A C   1 
ATOM   198  O O   . LEU A 1 76  ? 190.859 177.608 217.683 1.00 81.77  ? 76  LEU A O   1 
ATOM   199  C CB  . LEU A 1 76  ? 188.905 176.247 215.376 1.00 81.77  ? 76  LEU A CB  1 
ATOM   200  C CG  . LEU A 1 76  ? 187.988 175.063 215.684 1.00 81.77  ? 76  LEU A CG  1 
ATOM   201  C CD1 . LEU A 1 76  ? 188.146 173.972 214.639 1.00 81.77  ? 76  LEU A CD1 1 
ATOM   202  C CD2 . LEU A 1 76  ? 188.271 174.521 217.072 1.00 81.77  ? 76  LEU A CD2 1 
ATOM   203  N N   . PRO A 1 77  ? 190.882 178.749 215.748 1.00 85.06  ? 77  PRO A N   1 
ATOM   204  C CA  . PRO A 1 77  ? 192.269 179.182 216.002 1.00 85.06  ? 77  PRO A CA  1 
ATOM   205  C C   . PRO A 1 77  ? 192.449 179.955 217.297 1.00 85.06  ? 77  PRO A C   1 
ATOM   206  O O   . PRO A 1 77  ? 193.480 179.804 217.963 1.00 85.06  ? 77  PRO A O   1 
ATOM   207  C CB  . PRO A 1 77  ? 192.592 180.047 214.777 1.00 85.06  ? 77  PRO A CB  1 
ATOM   208  C CG  . PRO A 1 77  ? 191.677 179.559 213.722 1.00 85.06  ? 77  PRO A CG  1 
ATOM   209  C CD  . PRO A 1 77  ? 190.410 179.219 214.432 1.00 85.06  ? 77  PRO A CD  1 
ATOM   210  N N   . LYS A 1 78  ? 191.477 180.788 217.673 1.00 85.43  ? 78  LYS A N   1 
ATOM   211  C CA  . LYS A 1 78  ? 191.592 181.527 218.925 1.00 85.43  ? 78  LYS A CA  1 
ATOM   212  C C   . LYS A 1 78  ? 191.560 180.590 220.124 1.00 85.43  ? 78  LYS A C   1 
ATOM   213  O O   . LYS A 1 78  ? 192.303 180.787 221.093 1.00 85.43  ? 78  LYS A O   1 
ATOM   214  C CB  . LYS A 1 78  ? 190.477 182.564 219.026 1.00 85.43  ? 78  LYS A CB  1 
ATOM   215  C CG  . LYS A 1 78  ? 190.490 183.582 217.912 1.00 85.43  ? 78  LYS A CG  1 
ATOM   216  C CD  . LYS A 1 78  ? 189.620 184.766 218.264 1.00 85.43  ? 78  LYS A CD  1 
ATOM   217  C CE  . LYS A 1 78  ? 190.419 185.837 218.986 1.00 85.43  ? 78  LYS A CE  1 
ATOM   218  N NZ  . LYS A 1 78  ? 190.952 186.861 218.046 1.00 85.43  ? 78  LYS A NZ  1 
ATOM   219  N N   . ILE A 1 79  ? 190.696 179.574 220.081 1.00 84.03  ? 79  ILE A N   1 
ATOM   220  C CA  . ILE A 1 79  ? 190.660 178.582 221.151 1.00 84.03  ? 79  ILE A CA  1 
ATOM   221  C C   . ILE A 1 79  ? 191.995 177.860 221.241 1.00 84.03  ? 79  ILE A C   1 
ATOM   222  O O   . ILE A 1 79  ? 192.530 177.645 222.337 1.00 84.03  ? 79  ILE A O   1 
ATOM   223  C CB  . ILE A 1 79  ? 189.496 177.599 220.930 1.00 84.03  ? 79  ILE A CB  1 
ATOM   224  C CG1 . ILE A 1 79  ? 188.158 178.337 220.976 1.00 84.03  ? 79  ILE A CG1 1 
ATOM   225  C CG2 . ILE A 1 79  ? 189.524 176.494 221.969 1.00 84.03  ? 79  ILE A CG2 1 
ATOM   226  C CD1 . ILE A 1 79  ? 186.958 177.433 220.825 1.00 84.03  ? 79  ILE A CD1 1 
ATOM   227  N N   . GLN A 1 80  ? 192.561 177.485 220.090 1.00 89.78  ? 80  GLN A N   1 
ATOM   228  C CA  . GLN A 1 80  ? 193.869 176.837 220.089 1.00 89.78  ? 80  GLN A CA  1 
ATOM   229  C C   . GLN A 1 80  ? 194.928 177.730 220.719 1.00 89.78  ? 80  GLN A C   1 
ATOM   230  O O   . GLN A 1 80  ? 195.732 177.272 221.538 1.00 89.78  ? 80  GLN A O   1 
ATOM   231  C CB  . GLN A 1 80  ? 194.284 176.478 218.665 1.00 89.78  ? 80  GLN A CB  1 
ATOM   232  C CG  . GLN A 1 80  ? 195.596 175.720 218.593 1.00 89.78  ? 80  GLN A CG  1 
ATOM   233  C CD  . GLN A 1 80  ? 196.019 175.421 217.172 1.00 89.78  ? 80  GLN A CD  1 
ATOM   234  O OE1 . GLN A 1 80  ? 195.374 175.853 216.218 1.00 89.78  ? 80  GLN A OE1 1 
ATOM   235  N NE2 . GLN A 1 80  ? 197.104 174.670 217.023 1.00 89.78  ? 80  GLN A NE2 1 
ATOM   236  N N   . ASN A 1 81  ? 194.947 179.009 220.343 1.00 90.27  ? 81  ASN A N   1 
ATOM   237  C CA  . ASN A 1 81  ? 195.972 179.917 220.845 1.00 90.27  ? 81  ASN A CA  1 
ATOM   238  C C   . ASN A 1 81  ? 195.838 180.129 222.347 1.00 90.27  ? 81  ASN A C   1 
ATOM   239  O O   . ASN A 1 81  ? 196.831 180.078 223.081 1.00 90.27  ? 81  ASN A O   1 
ATOM   240  C CB  . ASN A 1 81  ? 195.895 181.251 220.103 1.00 90.27  ? 81  ASN A CB  1 
ATOM   241  C CG  . ASN A 1 81  ? 196.650 181.230 218.791 1.00 90.27  ? 81  ASN A CG  1 
ATOM   242  O OD1 . ASN A 1 81  ? 197.514 180.382 218.574 1.00 90.27  ? 81  ASN A OD1 1 
ATOM   243  N ND2 . ASN A 1 81  ? 196.326 182.165 217.906 1.00 90.27  ? 81  ASN A ND2 1 
ATOM   244  N N   . GLU A 1 82  ? 194.615 180.366 222.827 1.00 90.07  ? 82  GLU A N   1 
ATOM   245  C CA  . GLU A 1 82  ? 194.439 180.682 224.241 1.00 90.07  ? 82  GLU A CA  1 
ATOM   246  C C   . GLU A 1 82  ? 194.632 179.454 225.122 1.00 90.07  ? 82  GLU A C   1 
ATOM   247  O O   . GLU A 1 82  ? 195.309 179.528 226.154 1.00 90.07  ? 82  GLU A O   1 
ATOM   248  C CB  . GLU A 1 82  ? 193.064 181.302 224.480 1.00 90.07  ? 82  GLU A CB  1 
ATOM   249  C CG  . GLU A 1 82  ? 192.797 181.630 225.939 1.00 90.07  ? 82  GLU A CG  1 
ATOM   250  C CD  . GLU A 1 82  ? 191.689 182.645 226.119 1.00 90.07  ? 82  GLU A CD  1 
ATOM   251  O OE1 . GLU A 1 82  ? 191.188 183.167 225.102 1.00 90.07  ? 82  GLU A OE1 1 
ATOM   252  O OE2 . GLU A 1 82  ? 191.319 182.923 227.279 1.00 90.07  ? 82  GLU A OE2 1 
ATOM   253  N N   . LEU A 1 83  ? 194.052 178.317 224.740 1.00 90.66  ? 83  LEU A N   1 
ATOM   254  C CA  . LEU A 1 83  ? 194.123 177.131 225.583 1.00 90.66  ? 83  LEU A CA  1 
ATOM   255  C C   . LEU A 1 83  ? 195.375 176.299 225.345 1.00 90.66  ? 83  LEU A C   1 
ATOM   256  O O   . LEU A 1 83  ? 195.572 175.301 226.047 1.00 90.66  ? 83  LEU A O   1 
ATOM   257  C CB  . LEU A 1 83  ? 192.881 176.262 225.374 1.00 90.66  ? 83  LEU A CB  1 
ATOM   258  C CG  . LEU A 1 83  ? 191.580 176.833 225.935 1.00 90.66  ? 83  LEU A CG  1 
ATOM   259  C CD1 . LEU A 1 83  ? 190.437 175.856 225.732 1.00 90.66  ? 83  LEU A CD1 1 
ATOM   260  C CD2 . LEU A 1 83  ? 191.739 177.181 227.405 1.00 90.66  ? 83  LEU A CD2 1 
ATOM   261  N N   . SER A 1 84  ? 196.217 176.681 224.383 1.00 92.61  ? 84  SER A N   1 
ATOM   262  C CA  . SER A 1 84  ? 197.460 175.972 224.080 1.00 92.61  ? 84  SER A CA  1 
ATOM   263  C C   . SER A 1 84  ? 197.184 174.504 223.744 1.00 92.61  ? 84  SER A C   1 
ATOM   264  O O   . SER A 1 84  ? 197.631 173.582 224.428 1.00 92.61  ? 84  SER A O   1 
ATOM   265  C CB  . SER A 1 84  ? 198.458 176.100 225.236 1.00 92.61  ? 84  SER A CB  1 
ATOM   266  O OG  . SER A 1 84  ? 198.715 177.460 225.539 1.00 92.61  ? 84  SER A OG  1 
ATOM   267  N N   . LEU A 1 85  ? 196.430 174.305 222.670 1.00 92.12  ? 85  LEU A N   1 
ATOM   268  C CA  . LEU A 1 85  ? 196.036 172.979 222.221 1.00 92.12  ? 85  LEU A CA  1 
ATOM   269  C C   . LEU A 1 85  ? 196.829 172.567 220.987 1.00 92.12  ? 85  LEU A C   1 
ATOM   270  O O   . LEU A 1 85  ? 197.323 173.402 220.225 1.00 92.12  ? 85  LEU A O   1 
ATOM   271  C CB  . LEU A 1 85  ? 194.538 172.934 221.909 1.00 92.12  ? 85  LEU A CB  1 
ATOM   272  C CG  . LEU A 1 85  ? 193.592 173.549 222.937 1.00 92.12  ? 85  LEU A CG  1 
ATOM   273  C CD1 . LEU A 1 85  ? 192.175 173.565 222.398 1.00 92.12  ? 85  LEU A CD1 1 
ATOM   274  C CD2 . LEU A 1 85  ? 193.662 172.780 224.241 1.00 92.12  ? 85  LEU A CD2 1 
ATOM   275  N N   . SER A 1 86  ? 196.944 171.257 220.801 1.00 95.97  ? 86  SER A N   1 
ATOM   276  C CA  . SER A 1 86  ? 197.564 170.695 219.613 1.00 95.97  ? 86  SER A CA  1 
ATOM   277  C C   . SER A 1 86  ? 196.489 170.441 218.557 1.00 95.97  ? 86  SER A C   1 
ATOM   278  O O   . SER A 1 86  ? 195.345 170.885 218.684 1.00 95.97  ? 86  SER A O   1 
ATOM   279  C CB  . SER A 1 86  ? 198.330 169.423 219.968 1.00 95.97  ? 86  SER A CB  1 
ATOM   280  O OG  . SER A 1 86  ? 197.447 168.394 220.375 1.00 95.97  ? 86  SER A OG  1 
ATOM   281  N N   . ASP A 1 87  ? 196.851 169.724 217.491 1.00 96.53  ? 87  ASP A N   1 
ATOM   282  C CA  . ASP A 1 87  ? 195.870 169.382 216.467 1.00 96.53  ? 87  ASP A CA  1 
ATOM   283  C C   . ASP A 1 87  ? 194.812 168.431 217.015 1.00 96.53  ? 87  ASP A C   1 
ATOM   284  O O   . ASP A 1 87  ? 193.631 168.526 216.653 1.00 96.53  ? 87  ASP A O   1 
ATOM   285  C CB  . ASP A 1 87  ? 196.573 168.769 215.257 1.00 96.53  ? 87  ASP A CB  1 
ATOM   286  C CG  . ASP A 1 87  ? 195.851 169.057 213.957 1.00 96.53  ? 87  ASP A CG  1 
ATOM   287  O OD1 . ASP A 1 87  ? 194.845 169.797 213.985 1.00 96.53  ? 87  ASP A OD1 1 
ATOM   288  O OD2 . ASP A 1 87  ? 196.290 168.543 212.907 1.00 96.53  ? 87  ASP A OD2 1 
ATOM   289  N N   . ALA A 1 88  ? 195.219 167.507 217.890 1.00 94.94  ? 88  ALA A N   1 
ATOM   290  C CA  . ALA A 1 88  ? 194.265 166.586 218.497 1.00 94.94  ? 88  ALA A CA  1 
ATOM   291  C C   . ALA A 1 88  ? 193.226 167.334 219.319 1.00 94.94  ? 88  ALA A C   1 
ATOM   292  O O   . ALA A 1 88  ? 192.039 166.995 219.285 1.00 94.94  ? 88  ALA A O   1 
ATOM   293  C CB  . ALA A 1 88  ? 194.999 165.563 219.364 1.00 94.94  ? 88  ALA A CB  1 
ATOM   294  N N   . GLY A 1 89  ? 193.652 168.352 220.069 1.00 92.19  ? 89  GLY A N   1 
ATOM   295  C CA  . GLY A 1 89  ? 192.697 169.156 220.814 1.00 92.19  ? 89  GLY A CA  1 
ATOM   296  C C   . GLY A 1 89  ? 191.728 169.894 219.911 1.00 92.19  ? 89  GLY A C   1 
ATOM   297  O O   . GLY A 1 89  ? 190.531 169.977 220.202 1.00 92.19  ? 89  GLY A O   1 
ATOM   298  N N   . ARG A 1 90  ? 192.232 170.438 218.800 1.00 91.58  ? 90  ARG A N   1 
ATOM   299  C CA  . ARG A 1 90  ? 191.360 171.101 217.836 1.00 91.58  ? 90  ARG A CA  1 
ATOM   300  C C   . ARG A 1 90  ? 190.306 170.142 217.306 1.00 91.58  ? 90  ARG A C   1 
ATOM   301  O O   . ARG A 1 90  ? 189.119 170.479 217.238 1.00 91.58  ? 90  ARG A O   1 
ATOM   302  C CB  . ARG A 1 90  ? 192.180 171.658 216.675 1.00 91.58  ? 90  ARG A CB  1 
ATOM   303  C CG  . ARG A 1 90  ? 193.144 172.757 217.030 1.00 91.58  ? 90  ARG A CG  1 
ATOM   304  C CD  . ARG A 1 90  ? 193.889 173.182 215.784 1.00 91.58  ? 90  ARG A CD  1 
ATOM   305  N NE  . ARG A 1 90  ? 193.003 173.812 214.814 1.00 91.58  ? 90  ARG A NE  1 
ATOM   306  C CZ  . ARG A 1 90  ? 192.642 173.263 213.662 1.00 91.58  ? 90  ARG A CZ  1 
ATOM   307  N NH1 . ARG A 1 90  ? 193.069 172.063 213.305 1.00 91.58  ? 90  ARG A NH1 1 
ATOM   308  N NH2 . ARG A 1 90  ? 191.831 173.934 212.850 1.00 91.58  ? 90  ARG A NH2 1 
ATOM   309  N N   . SER A 1 91  ? 190.729 168.940 216.915 1.00 90.04  ? 91  SER A N   1 
ATOM   310  C CA  . SER A 1 91  ? 189.775 167.964 216.403 1.00 90.04  ? 91  SER A CA  1 
ATOM   311  C C   . SER A 1 91  ? 188.775 167.557 217.476 1.00 90.04  ? 91  SER A C   1 
ATOM   312  O O   . SER A 1 91  ? 187.576 167.429 217.200 1.00 90.04  ? 91  SER A O   1 
ATOM   313  C CB  . SER A 1 91  ? 190.515 166.741 215.865 1.00 90.04  ? 91  SER A CB  1 
ATOM   314  O OG  . SER A 1 91  ? 191.306 167.081 214.739 1.00 90.04  ? 91  SER A OG  1 
ATOM   315  N N   . TRP A 1 92  ? 189.243 167.369 218.712 1.00 86.43  ? 92  TRP A N   1 
ATOM   316  C CA  . TRP A 1 92  ? 188.365 166.870 219.762 1.00 86.43  ? 92  TRP A CA  1 
ATOM   317  C C   . TRP A 1 92  ? 187.362 167.920 220.215 1.00 86.43  ? 92  TRP A C   1 
ATOM   318  O O   . TRP A 1 92  ? 186.271 167.564 220.669 1.00 86.43  ? 92  TRP A O   1 
ATOM   319  C CB  . TRP A 1 92  ? 189.192 166.369 220.942 1.00 86.43  ? 92  TRP A CB  1 
ATOM   320  C CG  . TRP A 1 92  ? 189.296 164.882 220.969 1.00 86.43  ? 92  TRP A CG  1 
ATOM   321  C CD1 . TRP A 1 92  ? 190.325 164.123 220.496 1.00 86.43  ? 92  TRP A CD1 1 
ATOM   322  C CD2 . TRP A 1 92  ? 188.321 163.965 221.478 1.00 86.43  ? 92  TRP A CD2 1 
ATOM   323  N NE1 . TRP A 1 92  ? 190.055 162.790 220.686 1.00 86.43  ? 92  TRP A NE1 1 
ATOM   324  C CE2 . TRP A 1 92  ? 188.830 162.667 221.287 1.00 86.43  ? 92  TRP A CE2 1 
ATOM   325  C CE3 . TRP A 1 92  ? 187.070 164.117 222.081 1.00 86.43  ? 92  TRP A CE3 1 
ATOM   326  C CZ2 . TRP A 1 92  ? 188.132 161.528 221.679 1.00 86.43  ? 92  TRP A CZ2 1 
ATOM   327  C CZ3 . TRP A 1 92  ? 186.378 162.987 222.467 1.00 86.43  ? 92  TRP A CZ3 1 
ATOM   328  C CH2 . TRP A 1 92  ? 186.910 161.709 222.266 1.00 86.43  ? 92  TRP A CH2 1 
ATOM   329  N N   . VAL A 1 93  ? 187.695 169.206 220.086 1.00 81.57  ? 93  VAL A N   1 
ATOM   330  C CA  . VAL A 1 93  ? 186.726 170.247 220.423 1.00 81.57  ? 93  VAL A CA  1 
ATOM   331  C C   . VAL A 1 93  ? 185.473 170.103 219.566 1.00 81.57  ? 93  VAL A C   1 
ATOM   332  O O   . VAL A 1 93  ? 184.346 170.215 220.062 1.00 81.57  ? 93  VAL A O   1 
ATOM   333  C CB  . VAL A 1 93  ? 187.362 171.642 220.276 1.00 81.57  ? 93  VAL A CB  1 
ATOM   334  C CG1 . VAL A 1 93  ? 186.290 172.712 220.164 1.00 81.57  ? 93  VAL A CG1 1 
ATOM   335  C CG2 . VAL A 1 93  ? 188.274 171.932 221.453 1.00 81.57  ? 93  VAL A CG2 1 
ATOM   336  N N   . ILE A 1 94  ? 185.649 169.847 218.270 1.00 78.46  ? 94  ILE A N   1 
ATOM   337  C CA  . ILE A 1 94  ? 184.508 169.617 217.389 1.00 78.46  ? 94  ILE A CA  1 
ATOM   338  C C   . ILE A 1 94  ? 183.905 168.235 217.620 1.00 78.46  ? 94  ILE A C   1 
ATOM   339  O O   . ILE A 1 94  ? 182.681 168.069 217.591 1.00 78.46  ? 94  ILE A O   1 
ATOM   340  C CB  . ILE A 1 94  ? 184.927 169.813 215.921 1.00 78.46  ? 94  ILE A CB  1 
ATOM   341  C CG1 . ILE A 1 94  ? 185.642 171.152 215.745 1.00 78.46  ? 94  ILE A CG1 1 
ATOM   342  C CG2 . ILE A 1 94  ? 183.720 169.731 215.006 1.00 78.46  ? 94  ILE A CG2 1 
ATOM   343  C CD1 . ILE A 1 94  ? 184.826 172.341 216.187 1.00 78.46  ? 94  ILE A CD1 1 
ATOM   344  N N   . THR A 1 95  ? 184.749 167.225 217.849 1.00 77.91  ? 95  THR A N   1 
ATOM   345  C CA  . THR A 1 95  ? 184.268 165.849 217.931 1.00 77.91  ? 95  THR A CA  1 
ATOM   346  C C   . THR A 1 95  ? 183.430 165.599 219.181 1.00 77.91  ? 95  THR A C   1 
ATOM   347  O O   . THR A 1 95  ? 182.542 164.738 219.164 1.00 77.91  ? 95  THR A O   1 
ATOM   348  C CB  . THR A 1 95  ? 185.456 164.887 217.888 1.00 77.91  ? 95  THR A CB  1 
ATOM   349  O OG1 . THR A 1 95  ? 186.235 165.145 216.714 1.00 77.91  ? 95  THR A OG1 1 
ATOM   350  C CG2 . THR A 1 95  ? 184.988 163.442 217.862 1.00 77.91  ? 95  THR A CG2 1 
ATOM   351  N N   . ALA A 1 96  ? 183.697 166.324 220.269 1.00 71.34  ? 96  ALA A N   1 
ATOM   352  C CA  . ALA A 1 96  ? 182.980 166.078 221.515 1.00 71.34  ? 96  ALA A CA  1 
ATOM   353  C C   . ALA A 1 96  ? 181.490 166.349 221.362 1.00 71.34  ? 96  ALA A C   1 
ATOM   354  O O   . ALA A 1 96  ? 180.659 165.599 221.887 1.00 71.34  ? 96  ALA A O   1 
ATOM   355  C CB  . ALA A 1 96  ? 183.572 166.930 222.634 1.00 71.34  ? 96  ALA A CB  1 
ATOM   356  N N   . TYR A 1 97  ? 181.131 167.419 220.655 1.00 65.10  ? 97  TYR A N   1 
ATOM   357  C CA  . TYR A 1 97  ? 179.721 167.716 220.429 1.00 65.10  ? 97  TYR A CA  1 
ATOM   358  C C   . TYR A 1 97  ? 179.066 166.642 219.570 1.00 65.10  ? 97  TYR A C   1 
ATOM   359  O O   . TYR A 1 97  ? 177.988 166.136 219.904 1.00 65.10  ? 97  TYR A O   1 
ATOM   360  C CB  . TYR A 1 97  ? 179.581 169.092 219.777 1.00 65.10  ? 97  TYR A CB  1 
ATOM   361  C CG  . TYR A 1 97  ? 178.170 169.464 219.387 1.00 65.10  ? 97  TYR A CG  1 
ATOM   362  C CD1 . TYR A 1 97  ? 177.322 170.084 220.290 1.00 65.10  ? 97  TYR A CD1 1 
ATOM   363  C CD2 . TYR A 1 97  ? 177.691 169.210 218.110 1.00 65.10  ? 97  TYR A CD2 1 
ATOM   364  C CE1 . TYR A 1 97  ? 176.037 170.430 219.937 1.00 65.10  ? 97  TYR A CE1 1 
ATOM   365  C CE2 . TYR A 1 97  ? 176.407 169.551 217.750 1.00 65.10  ? 97  TYR A CE2 1 
ATOM   366  C CZ  . TYR A 1 97  ? 175.585 170.161 218.666 1.00 65.10  ? 97  TYR A CZ  1 
ATOM   367  O OH  . TYR A 1 97  ? 174.304 170.504 218.311 1.00 65.10  ? 97  TYR A OH  1 
ATOM   368  N N   . VAL A 1 98  ? 179.718 166.273 218.465 1.00 67.77  ? 98  VAL A N   1 
ATOM   369  C CA  . VAL A 1 98  ? 179.125 165.344 217.509 1.00 67.77  ? 98  VAL A CA  1 
ATOM   370  C C   . VAL A 1 98  ? 178.945 163.968 218.134 1.00 67.77  ? 98  VAL A C   1 
ATOM   371  O O   . VAL A 1 98  ? 177.969 163.266 217.844 1.00 67.77  ? 98  VAL A O   1 
ATOM   372  C CB  . VAL A 1 98  ? 179.980 165.279 216.232 1.00 67.77  ? 98  VAL A CB  1 
ATOM   373  C CG1 . VAL A 1 98  ? 179.361 164.330 215.224 1.00 67.77  ? 98  VAL A CG1 1 
ATOM   374  C CG2 . VAL A 1 98  ? 180.140 166.664 215.631 1.00 67.77  ? 98  VAL A CG2 1 
ATOM   375  N N   . LEU A 1 99  ? 179.875 163.561 219.003 1.00 69.43  ? 99  LEU A N   1 
ATOM   376  C CA  . LEU A 1 99  ? 179.803 162.230 219.598 1.00 69.43  ? 99  LEU A CA  1 
ATOM   377  C C   . LEU A 1 99  ? 178.493 162.031 220.350 1.00 69.43  ? 99  LEU A C   1 
ATOM   378  O O   . LEU A 1 99  ? 177.749 161.080 220.084 1.00 69.43  ? 99  LEU A O   1 
ATOM   379  C CB  . LEU A 1 99  ? 180.995 162.016 220.528 1.00 69.43  ? 99  LEU A CB  1 
ATOM   380  C CG  . LEU A 1 99  ? 181.310 160.584 220.954 1.00 69.43  ? 99  LEU A CG  1 
ATOM   381  C CD1 . LEU A 1 99  ? 181.895 159.801 219.794 1.00 69.43  ? 99  LEU A CD1 1 
ATOM   382  C CD2 . LEU A 1 99  ? 182.263 160.585 222.134 1.00 69.43  ? 99  LEU A CD2 1 
ATOM   383  N N   . THR A 1 100 ? 178.174 162.941 221.271 1.00 65.18  ? 100 THR A N   1 
ATOM   384  C CA  . THR A 1 100 ? 176.940 162.816 222.033 1.00 65.18  ? 100 THR A CA  1 
ATOM   385  C C   . THR A 1 100 ? 175.719 163.325 221.279 1.00 65.18  ? 100 THR A C   1 
ATOM   386  O O   . THR A 1 100 ? 174.593 163.009 221.676 1.00 65.18  ? 100 THR A O   1 
ATOM   387  C CB  . THR A 1 100 ? 177.059 163.551 223.367 1.00 65.18  ? 100 THR A CB  1 
ATOM   388  O OG1 . THR A 1 100 ? 177.290 164.944 223.130 1.00 65.18  ? 100 THR A OG1 1 
ATOM   389  C CG2 . THR A 1 100 ? 178.198 162.982 224.185 1.00 65.18  ? 100 THR A CG2 1 
ATOM   390  N N   . PHE A 1 101 ? 175.902 164.101 220.207 1.00 64.42  ? 101 PHE A N   1 
ATOM   391  C CA  . PHE A 1 101 ? 174.754 164.482 219.393 1.00 64.42  ? 101 PHE A CA  1 
ATOM   392  C C   . PHE A 1 101 ? 174.250 163.300 218.577 1.00 64.42  ? 101 PHE A C   1 
ATOM   393  O O   . PHE A 1 101 ? 173.038 163.081 218.477 1.00 64.42  ? 101 PHE A O   1 
ATOM   394  C CB  . PHE A 1 101 ? 175.118 165.649 218.480 1.00 64.42  ? 101 PHE A CB  1 
ATOM   395  C CG  . PHE A 1 101 ? 173.990 166.110 217.607 1.00 64.42  ? 101 PHE A CG  1 
ATOM   396  C CD1 . PHE A 1 101 ? 172.743 166.363 218.144 1.00 64.42  ? 101 PHE A CD1 1 
ATOM   397  C CD2 . PHE A 1 101 ? 174.176 166.293 216.250 1.00 64.42  ? 101 PHE A CD2 1 
ATOM   398  C CE1 . PHE A 1 101 ? 171.703 166.790 217.347 1.00 64.42  ? 101 PHE A CE1 1 
ATOM   399  C CE2 . PHE A 1 101 ? 173.138 166.719 215.448 1.00 64.42  ? 101 PHE A CE2 1 
ATOM   400  C CZ  . PHE A 1 101 ? 171.900 166.967 215.999 1.00 64.42  ? 101 PHE A CZ  1 
ATOM   401  N N   . GLY A 1 102 ? 175.164 162.528 217.985 1.00 67.42  ? 102 GLY A N   1 
ATOM   402  C CA  . GLY A 1 102 ? 174.771 161.347 217.241 1.00 67.42  ? 102 GLY A CA  1 
ATOM   403  C C   . GLY A 1 102 ? 174.541 160.116 218.088 1.00 67.42  ? 102 GLY A C   1 
ATOM   404  O O   . GLY A 1 102 ? 173.826 159.207 217.656 1.00 67.42  ? 102 GLY A O   1 
ATOM   405  N N   . GLY A 1 103 ? 175.133 160.059 219.282 1.00 69.75  ? 103 GLY A N   1 
ATOM   406  C CA  . GLY A 1 103 ? 174.936 158.899 220.133 1.00 69.75  ? 103 GLY A CA  1 
ATOM   407  C C   . GLY A 1 103 ? 173.524 158.781 220.677 1.00 69.75  ? 103 GLY A C   1 
ATOM   408  O O   . GLY A 1 103 ? 172.958 157.686 220.719 1.00 69.75  ? 103 GLY A O   1 
ATOM   409  N N   . LEU A 1 104 ? 172.932 159.902 221.092 1.00 66.13  ? 104 LEU A N   1 
ATOM   410  C CA  . LEU A 1 104 ? 171.682 159.889 221.843 1.00 66.13  ? 104 LEU A CA  1 
ATOM   411  C C   . LEU A 1 104 ? 170.503 160.439 221.047 1.00 66.13  ? 104 LEU A C   1 
ATOM   412  O O   . LEU A 1 104 ? 169.518 160.885 221.640 1.00 66.13  ? 104 LEU A O   1 
ATOM   413  C CB  . LEU A 1 104 ? 171.840 160.670 223.148 1.00 66.13  ? 104 LEU A CB  1 
ATOM   414  C CG  . LEU A 1 104 ? 172.504 159.960 224.330 1.00 66.13  ? 104 LEU A CG  1 
ATOM   415  C CD1 . LEU A 1 104 ? 174.008 159.876 224.150 1.00 66.13  ? 104 LEU A CD1 1 
ATOM   416  C CD2 . LEU A 1 104 ? 172.163 160.659 225.632 1.00 66.13  ? 104 LEU A CD2 1 
ATOM   417  N N   . MET A 1 105 ? 170.580 160.415 219.716 1.00 66.96  ? 105 MET A N   1 
ATOM   418  C CA  . MET A 1 105 ? 169.443 160.842 218.906 1.00 66.96  ? 105 MET A CA  1 
ATOM   419  C C   . MET A 1 105 ? 168.275 159.870 219.032 1.00 66.96  ? 105 MET A C   1 
ATOM   420  O O   . MET A 1 105 ? 167.134 160.285 219.273 1.00 66.96  ? 105 MET A O   1 
ATOM   421  C CB  . MET A 1 105 ? 169.873 160.969 217.445 1.00 66.96  ? 105 MET A CB  1 
ATOM   422  C CG  . MET A 1 105 ? 168.811 161.519 216.513 1.00 66.96  ? 105 MET A CG  1 
ATOM   423  S SD  . MET A 1 105 ? 168.331 163.207 216.893 1.00 66.96  ? 105 MET A SD  1 
ATOM   424  C CE  . MET A 1 105 ? 169.790 164.073 216.332 1.00 66.96  ? 105 MET A CE  1 
ATOM   425  N N   . LEU A 1 106 ? 168.546 158.571 218.880 1.00 68.45  ? 106 LEU A N   1 
ATOM   426  C CA  . LEU A 1 106 ? 167.480 157.574 218.892 1.00 68.45  ? 106 LEU A CA  1 
ATOM   427  C C   . LEU A 1 106 ? 166.803 157.499 220.253 1.00 68.45  ? 106 LEU A C   1 
ATOM   428  O O   . LEU A 1 106 ? 165.578 157.359 220.337 1.00 68.45  ? 106 LEU A O   1 
ATOM   429  C CB  . LEU A 1 106 ? 168.042 156.211 218.496 1.00 68.45  ? 106 LEU A CB  1 
ATOM   430  C CG  . LEU A 1 106 ? 168.139 155.942 216.994 1.00 68.45  ? 106 LEU A CG  1 
ATOM   431  C CD1 . LEU A 1 106 ? 168.469 154.483 216.729 1.00 68.45  ? 106 LEU A CD1 1 
ATOM   432  C CD2 . LEU A 1 106 ? 166.855 156.345 216.288 1.00 68.45  ? 106 LEU A CD2 1 
ATOM   433  N N   . LEU A 1 107 ? 167.584 157.573 221.332 1.00 69.21  ? 107 LEU A N   1 
ATOM   434  C CA  . LEU A 1 107 ? 166.999 157.585 222.668 1.00 69.21  ? 107 LEU A CA  1 
ATOM   435  C C   . LEU A 1 107 ? 166.155 158.832 222.887 1.00 69.21  ? 107 LEU A C   1 
ATOM   436  O O   . LEU A 1 107 ? 165.087 158.767 223.508 1.00 69.21  ? 107 LEU A O   1 
ATOM   437  C CB  . LEU A 1 107 ? 168.100 157.490 223.723 1.00 69.21  ? 107 LEU A CB  1 
ATOM   438  C CG  . LEU A 1 107 ? 167.699 157.785 225.170 1.00 69.21  ? 107 LEU A CG  1 
ATOM   439  C CD1 . LEU A 1 107 ? 166.634 156.815 225.648 1.00 69.21  ? 107 LEU A CD1 1 
ATOM   440  C CD2 . LEU A 1 107 ? 168.914 157.736 226.076 1.00 69.21  ? 107 LEU A CD2 1 
ATOM   441  N N   . GLY A 1 108 ? 166.620 159.980 222.391 1.00 65.93  ? 108 GLY A N   1 
ATOM   442  C CA  . GLY A 1 108 ? 165.857 161.205 222.545 1.00 65.93  ? 108 GLY A CA  1 
ATOM   443  C C   . GLY A 1 108 ? 164.578 161.212 221.737 1.00 65.93  ? 108 GLY A C   1 
ATOM   444  O O   . GLY A 1 108 ? 163.624 161.911 222.087 1.00 65.93  ? 108 GLY A O   1 
ATOM   445  N N   . GLY A 1 109 ? 164.536 160.442 220.648 1.00 67.27  ? 109 GLY A N   1 
ATOM   446  C CA  . GLY A 1 109 ? 163.313 160.337 219.873 1.00 67.27  ? 109 GLY A CA  1 
ATOM   447  C C   . GLY A 1 109 ? 162.196 159.596 220.579 1.00 67.27  ? 109 GLY A C   1 
ATOM   448  O O   . GLY A 1 109 ? 161.022 159.844 220.289 1.00 67.27  ? 109 GLY A O   1 
ATOM   449  N N   . ARG A 1 110 ? 162.535 158.697 221.501 1.00 72.89  ? 110 ARG A N   1 
ATOM   450  C CA  . ARG A 1 110 ? 161.547 157.937 222.255 1.00 72.89  ? 110 ARG A CA  1 
ATOM   451  C C   . ARG A 1 110 ? 161.350 158.457 223.673 1.00 72.89  ? 110 ARG A C   1 
ATOM   452  O O   . ARG A 1 110 ? 160.322 158.161 224.289 1.00 72.89  ? 110 ARG A O   1 
ATOM   453  C CB  . ARG A 1 110 ? 161.951 156.456 222.296 1.00 72.89  ? 110 ARG A CB  1 
ATOM   454  C CG  . ARG A 1 110 ? 160.934 155.522 222.931 1.00 72.89  ? 110 ARG A CG  1 
ATOM   455  C CD  . ARG A 1 110 ? 159.563 155.634 222.285 1.00 72.89  ? 110 ARG A CD  1 
ATOM   456  N NE  . ARG A 1 110 ? 159.417 154.764 221.124 1.00 72.89  ? 110 ARG A NE  1 
ATOM   457  C CZ  . ARG A 1 110 ? 158.300 154.642 220.420 1.00 72.89  ? 110 ARG A CZ  1 
ATOM   458  N NH1 . ARG A 1 110 ? 157.210 155.324 220.729 1.00 72.89  ? 110 ARG A NH1 1 
ATOM   459  N NH2 . ARG A 1 110 ? 158.274 153.809 219.385 1.00 72.89  ? 110 ARG A NH2 1 
ATOM   460  N N   . LEU A 1 111 ? 162.297 159.242 224.192 1.00 72.04  ? 111 LEU A N   1 
ATOM   461  C CA  . LEU A 1 111 ? 162.183 159.748 225.556 1.00 72.04  ? 111 LEU A CA  1 
ATOM   462  C C   . LEU A 1 111 ? 160.974 160.660 225.730 1.00 72.04  ? 111 LEU A C   1 
ATOM   463  O O   . LEU A 1 111 ? 160.439 160.773 226.838 1.00 72.04  ? 111 LEU A O   1 
ATOM   464  C CB  . LEU A 1 111 ? 163.473 160.479 225.935 1.00 72.04  ? 111 LEU A CB  1 
ATOM   465  C CG  . LEU A 1 111 ? 163.512 161.356 227.184 1.00 72.04  ? 111 LEU A CG  1 
ATOM   466  C CD1 . LEU A 1 111 ? 163.603 160.498 228.428 1.00 72.04  ? 111 LEU A CD1 1 
ATOM   467  C CD2 . LEU A 1 111 ? 164.684 162.316 227.108 1.00 72.04  ? 111 LEU A CD2 1 
ATOM   468  N N   . GLY A 1 112 ? 160.521 161.308 224.656 1.00 73.71  ? 112 GLY A N   1 
ATOM   469  C CA  . GLY A 1 112 ? 159.410 162.238 224.767 1.00 73.71  ? 112 GLY A CA  1 
ATOM   470  C C   . GLY A 1 112 ? 158.073 161.587 225.055 1.00 73.71  ? 112 GLY A C   1 
ATOM   471  O O   . GLY A 1 112 ? 157.171 162.253 225.572 1.00 73.71  ? 112 GLY A O   1 
ATOM   472  N N   . ASP A 1 113 ? 157.921 160.303 224.728 1.00 81.47  ? 113 ASP A N   1 
ATOM   473  C CA  . ASP A 1 113 ? 156.659 159.616 224.978 1.00 81.47  ? 113 ASP A CA  1 
ATOM   474  C C   . ASP A 1 113 ? 156.470 159.295 226.456 1.00 81.47  ? 113 ASP A C   1 
ATOM   475  O O   . ASP A 1 113 ? 155.353 159.393 226.975 1.00 81.47  ? 113 ASP A O   1 
ATOM   476  C CB  . ASP A 1 113 ? 156.583 158.335 224.147 1.00 81.47  ? 113 ASP A CB  1 
ATOM   477  C CG  . ASP A 1 113 ? 156.430 158.609 222.665 1.00 81.47  ? 113 ASP A CG  1 
ATOM   478  O OD1 . ASP A 1 113 ? 155.848 159.653 222.310 1.00 81.47  ? 113 ASP A OD1 1 
ATOM   479  O OD2 . ASP A 1 113 ? 156.887 157.777 221.855 1.00 81.47  ? 113 ASP A OD2 1 
ATOM   480  N N   . THR A 1 114 ? 157.542 158.907 227.146 1.00 81.41  ? 114 THR A N   1 
ATOM   481  C CA  . THR A 1 114 ? 157.449 158.466 228.531 1.00 81.41  ? 114 THR A CA  1 
ATOM   482  C C   . THR A 1 114 ? 157.547 159.602 229.542 1.00 81.41  ? 114 THR A C   1 
ATOM   483  O O   . THR A 1 114 ? 157.324 159.365 230.734 1.00 81.41  ? 114 THR A O   1 
ATOM   484  C CB  . THR A 1 114 ? 158.540 157.434 228.833 1.00 81.41  ? 114 THR A CB  1 
ATOM   485  O OG1 . THR A 1 114 ? 158.449 157.031 230.205 1.00 81.41  ? 114 THR A OG1 1 
ATOM   486  C CG2 . THR A 1 114 ? 159.915 158.022 228.579 1.00 81.41  ? 114 THR A CG2 1 
ATOM   487  N N   . ILE A 1 115 ? 157.871 160.818 229.108 1.00 76.68  ? 115 ILE A N   1 
ATOM   488  C CA  . ILE A 1 115 ? 158.013 161.966 229.995 1.00 76.68  ? 115 ILE A CA  1 
ATOM   489  C C   . ILE A 1 115 ? 157.088 163.106 229.585 1.00 76.68  ? 115 ILE A C   1 
ATOM   490  O O   . ILE A 1 115 ? 156.365 163.664 230.415 1.00 76.68  ? 115 ILE A O   1 
ATOM   491  C CB  . ILE A 1 115 ? 159.480 162.449 230.058 1.00 76.68  ? 115 ILE A CB  1 
ATOM   492  C CG1 . ILE A 1 115 ? 160.292 161.560 230.998 1.00 76.68  ? 115 ILE A CG1 1 
ATOM   493  C CG2 . ILE A 1 115 ? 159.556 163.895 230.510 1.00 76.68  ? 115 ILE A CG2 1 
ATOM   494  C CD1 . ILE A 1 115 ? 161.711 162.034 231.205 1.00 76.68  ? 115 ILE A CD1 1 
ATOM   495  N N   . GLY A 1 116 ? 157.092 163.459 228.303 1.00 72.95  ? 116 GLY A N   1 
ATOM   496  C CA  . GLY A 1 116 ? 156.303 164.568 227.805 1.00 72.95  ? 116 GLY A CA  1 
ATOM   497  C C   . GLY A 1 116 ? 157.076 165.391 226.798 1.00 72.95  ? 116 GLY A C   1 
ATOM   498  O O   . GLY A 1 116 ? 158.233 165.742 227.043 1.00 72.95  ? 116 GLY A O   1 
ATOM   499  N N   . ARG A 1 117 ? 156.455 165.701 225.657 1.00 66.49  ? 117 ARG A N   1 
ATOM   500  C CA  . ARG A 1 117 ? 157.173 166.404 224.598 1.00 66.49  ? 117 ARG A CA  1 
ATOM   501  C C   . ARG A 1 117 ? 157.554 167.817 225.021 1.00 66.49  ? 117 ARG A C   1 
ATOM   502  O O   . ARG A 1 117 ? 158.687 168.253 224.787 1.00 66.49  ? 117 ARG A O   1 
ATOM   503  C CB  . ARG A 1 117 ? 156.334 166.432 223.324 1.00 66.49  ? 117 ARG A CB  1 
ATOM   504  C CG  . ARG A 1 117 ? 156.045 165.057 222.766 1.00 66.49  ? 117 ARG A CG  1 
ATOM   505  C CD  . ARG A 1 117 ? 155.654 165.116 221.305 1.00 66.49  ? 117 ARG A CD  1 
ATOM   506  N NE  . ARG A 1 117 ? 155.005 163.883 220.881 1.00 66.49  ? 117 ARG A NE  1 
ATOM   507  C CZ  . ARG A 1 117 ? 155.646 162.755 220.613 1.00 66.49  ? 117 ARG A CZ  1 
ATOM   508  N NH1 . ARG A 1 117 ? 156.963 162.673 220.692 1.00 66.49  ? 117 ARG A NH1 1 
ATOM   509  N NH2 . ARG A 1 117 ? 154.947 161.681 220.260 1.00 66.49  ? 117 ARG A NH2 1 
ATOM   510  N N   . LYS A 1 118 ? 156.627 168.547 225.641 1.00 69.81  ? 118 LYS A N   1 
ATOM   511  C CA  . LYS A 1 118 ? 156.940 169.896 226.103 1.00 69.81  ? 118 LYS A CA  1 
ATOM   512  C C   . LYS A 1 118 ? 158.030 169.875 227.168 1.00 69.81  ? 118 LYS A C   1 
ATOM   513  O O   . LYS A 1 118 ? 158.974 170.675 227.121 1.00 69.81  ? 118 LYS A O   1 
ATOM   514  C CB  . LYS A 1 118 ? 155.675 170.566 226.637 1.00 69.81  ? 118 LYS A CB  1 
ATOM   515  C CG  . LYS A 1 118 ? 155.750 172.077 226.701 1.00 69.81  ? 118 LYS A CG  1 
ATOM   516  C CD  . LYS A 1 118 ? 154.474 172.659 227.276 1.00 69.81  ? 118 LYS A CD  1 
ATOM   517  C CE  . LYS A 1 118 ? 154.770 173.662 228.371 1.00 69.81  ? 118 LYS A CE  1 
ATOM   518  N NZ  . LYS A 1 118 ? 153.579 174.498 228.685 1.00 69.81  ? 118 LYS A NZ  1 
ATOM   519  N N   . ARG A 1 119 ? 157.920 168.957 228.131 1.00 68.45  ? 119 ARG A N   1 
ATOM   520  C CA  . ARG A 1 119 ? 158.917 168.866 229.190 1.00 68.45  ? 119 ARG A CA  1 
ATOM   521  C C   . ARG A 1 119 ? 160.280 168.476 228.635 1.00 68.45  ? 119 ARG A C   1 
ATOM   522  O O   . ARG A 1 119 ? 161.304 169.041 229.035 1.00 68.45  ? 119 ARG A O   1 
ATOM   523  C CB  . ARG A 1 119 ? 158.461 167.866 230.251 1.00 68.45  ? 119 ARG A CB  1 
ATOM   524  C CG  . ARG A 1 119 ? 159.386 167.773 231.450 1.00 68.45  ? 119 ARG A CG  1 
ATOM   525  C CD  . ARG A 1 119 ? 158.805 166.881 232.532 1.00 68.45  ? 119 ARG A CD  1 
ATOM   526  N NE  . ARG A 1 119 ? 157.349 166.852 232.496 1.00 68.45  ? 119 ARG A NE  1 
ATOM   527  C CZ  . ARG A 1 119 ? 156.566 167.646 233.214 1.00 68.45  ? 119 ARG A CZ  1 
ATOM   528  N NH1 . ARG A 1 119 ? 157.068 168.550 234.039 1.00 68.45  ? 119 ARG A NH1 1 
ATOM   529  N NH2 . ARG A 1 119 ? 155.246 167.530 233.101 1.00 68.45  ? 119 ARG A NH2 1 
ATOM   530  N N   . THR A 1 120 ? 160.314 167.512 227.712 1.00 64.05  ? 120 THR A N   1 
ATOM   531  C CA  . THR A 1 120 ? 161.581 167.111 227.106 1.00 64.05  ? 120 THR A CA  1 
ATOM   532  C C   . THR A 1 120 ? 162.204 168.257 226.322 1.00 64.05  ? 120 THR A C   1 
ATOM   533  O O   . THR A 1 120 ? 163.416 168.488 226.403 1.00 64.05  ? 120 THR A O   1 
ATOM   534  C CB  . THR A 1 120 ? 161.370 165.900 226.199 1.00 64.05  ? 120 THR A CB  1 
ATOM   535  O OG1 . THR A 1 120 ? 160.677 164.876 226.920 1.00 64.05  ? 120 THR A OG1 1 
ATOM   536  C CG2 . THR A 1 120 ? 162.699 165.356 225.721 1.00 64.05  ? 120 THR A CG2 1 
ATOM   537  N N   . PHE A 1 121 ? 161.389 168.986 225.558 1.00 60.89  ? 121 PHE A N   1 
ATOM   538  C CA  . PHE A 1 121 ? 161.892 170.121 224.792 1.00 60.89  ? 121 PHE A CA  1 
ATOM   539  C C   . PHE A 1 121 ? 162.500 171.171 225.713 1.00 60.89  ? 121 PHE A C   1 
ATOM   540  O O   . PHE A 1 121 ? 163.616 171.656 225.477 1.00 60.89  ? 121 PHE A O   1 
ATOM   541  C CB  . PHE A 1 121 ? 160.753 170.715 223.962 1.00 60.89  ? 121 PHE A CB  1 
ATOM   542  C CG  . PHE A 1 121 ? 161.207 171.607 222.845 1.00 60.89  ? 121 PHE A CG  1 
ATOM   543  C CD1 . PHE A 1 121 ? 162.063 171.138 221.867 1.00 60.89  ? 121 PHE A CD1 1 
ATOM   544  C CD2 . PHE A 1 121 ? 160.765 172.915 222.765 1.00 60.89  ? 121 PHE A CD2 1 
ATOM   545  C CE1 . PHE A 1 121 ? 162.476 171.958 220.838 1.00 60.89  ? 121 PHE A CE1 1 
ATOM   546  C CE2 . PHE A 1 121 ? 161.176 173.738 221.739 1.00 60.89  ? 121 PHE A CE2 1 
ATOM   547  C CZ  . PHE A 1 121 ? 162.033 173.258 220.775 1.00 60.89  ? 121 PHE A CZ  1 
ATOM   548  N N   . ILE A 1 122 ? 161.785 171.519 226.785 1.00 61.02  ? 122 ILE A N   1 
ATOM   549  C CA  . ILE A 1 122 ? 162.275 172.544 227.701 1.00 61.02  ? 122 ILE A CA  1 
ATOM   550  C C   . ILE A 1 122 ? 163.547 172.081 228.400 1.00 61.02  ? 122 ILE A C   1 
ATOM   551  O O   . ILE A 1 122 ? 164.497 172.855 228.555 1.00 61.02  ? 122 ILE A O   1 
ATOM   552  C CB  . ILE A 1 122 ? 161.175 172.929 228.706 1.00 61.02  ? 122 ILE A CB  1 
ATOM   553  C CG1 . ILE A 1 122 ? 160.025 173.626 227.985 1.00 61.02  ? 122 ILE A CG1 1 
ATOM   554  C CG2 . ILE A 1 122 ? 161.731 173.832 229.787 1.00 61.02  ? 122 ILE A CG2 1 
ATOM   555  C CD1 . ILE A 1 122 ? 158.842 173.906 228.867 1.00 61.02  ? 122 ILE A CD1 1 
ATOM   556  N N   . VAL A 1 123 ? 163.591 170.818 228.834 1.00 59.91  ? 123 VAL A N   1 
ATOM   557  C CA  . VAL A 1 123 ? 164.777 170.309 229.519 1.00 59.91  ? 123 VAL A CA  1 
ATOM   558  C C   . VAL A 1 123 ? 165.982 170.317 228.586 1.00 59.91  ? 123 VAL A C   1 
ATOM   559  O O   . VAL A 1 123 ? 167.090 170.700 228.983 1.00 59.91  ? 123 VAL A O   1 
ATOM   560  C CB  . VAL A 1 123 ? 164.507 168.904 230.085 1.00 59.91  ? 123 VAL A CB  1 
ATOM   561  C CG1 . VAL A 1 123 ? 165.809 168.207 230.427 1.00 59.91  ? 123 VAL A CG1 1 
ATOM   562  C CG2 . VAL A 1 123 ? 163.616 168.993 231.310 1.00 59.91  ? 123 VAL A CG2 1 
ATOM   563  N N   . GLY A 1 124 ? 165.789 169.898 227.334 1.00 59.10  ? 124 GLY A N   1 
ATOM   564  C CA  . GLY A 1 124 ? 166.889 169.917 226.385 1.00 59.10  ? 124 GLY A CA  1 
ATOM   565  C C   . GLY A 1 124 ? 167.409 171.315 226.116 1.00 59.10  ? 124 GLY A C   1 
ATOM   566  O O   . GLY A 1 124 ? 168.623 171.544 226.101 1.00 59.10  ? 124 GLY A O   1 
ATOM   567  N N   . VAL A 1 125 ? 166.502 172.274 225.912 1.00 58.88  ? 125 VAL A N   1 
ATOM   568  C CA  . VAL A 1 125 ? 166.938 173.645 225.654 1.00 58.88  ? 125 VAL A CA  1 
ATOM   569  C C   . VAL A 1 125 ? 167.647 174.222 226.874 1.00 58.88  ? 125 VAL A C   1 
ATOM   570  O O   . VAL A 1 125 ? 168.652 174.933 226.748 1.00 58.88  ? 125 VAL A O   1 
ATOM   571  C CB  . VAL A 1 125 ? 165.748 174.518 225.217 1.00 58.88  ? 125 VAL A CB  1 
ATOM   572  C CG1 . VAL A 1 125 ? 166.195 175.946 224.999 1.00 58.88  ? 125 VAL A CG1 1 
ATOM   573  C CG2 . VAL A 1 125 ? 165.134 173.970 223.945 1.00 58.88  ? 125 VAL A CG2 1 
ATOM   574  N N   . ALA A 1 126 ? 167.143 173.921 228.075 1.00 57.95  ? 126 ALA A N   1 
ATOM   575  C CA  . ALA A 1 126 ? 167.777 174.420 229.291 1.00 57.95  ? 126 ALA A CA  1 
ATOM   576  C C   . ALA A 1 126 ? 169.177 173.845 229.466 1.00 57.95  ? 126 ALA A C   1 
ATOM   577  O O   . ALA A 1 126 ? 170.109 174.566 229.842 1.00 57.95  ? 126 ALA A O   1 
ATOM   578  C CB  . ALA A 1 126 ? 166.909 174.096 230.504 1.00 57.95  ? 126 ALA A CB  1 
ATOM   579  N N   . LEU A 1 127 ? 169.344 172.546 229.207 1.00 58.56  ? 127 LEU A N   1 
ATOM   580  C CA  . LEU A 1 127 ? 170.669 171.942 229.305 1.00 58.56  ? 127 LEU A CA  1 
ATOM   581  C C   . LEU A 1 127 ? 171.618 172.533 228.272 1.00 58.56  ? 127 LEU A C   1 
ATOM   582  O O   . LEU A 1 127 ? 172.795 172.779 228.567 1.00 58.56  ? 127 LEU A O   1 
ATOM   583  C CB  . LEU A 1 127 ? 170.571 170.427 229.143 1.00 58.56  ? 127 LEU A CB  1 
ATOM   584  C CG  . LEU A 1 127 ? 171.876 169.650 229.318 1.00 58.56  ? 127 LEU A CG  1 
ATOM   585  C CD1 . LEU A 1 127 ? 172.533 170.000 230.639 1.00 58.56  ? 127 LEU A CD1 1 
ATOM   586  C CD2 . LEU A 1 127 ? 171.628 168.157 229.224 1.00 58.56  ? 127 LEU A CD2 1 
ATOM   587  N N   . PHE A 1 128 ? 171.124 172.776 227.056 1.00 59.63  ? 128 PHE A N   1 
ATOM   588  C CA  . PHE A 1 128 ? 171.950 173.412 226.035 1.00 59.63  ? 128 PHE A CA  1 
ATOM   589  C C   . PHE A 1 128 ? 172.410 174.792 226.488 1.00 59.63  ? 128 PHE A C   1 
ATOM   590  O O   . PHE A 1 128 ? 173.585 175.145 226.346 1.00 59.63  ? 128 PHE A O   1 
ATOM   591  C CB  . PHE A 1 128 ? 171.172 173.505 224.722 1.00 59.63  ? 128 PHE A CB  1 
ATOM   592  C CG  . PHE A 1 128 ? 171.992 173.984 223.558 1.00 59.63  ? 128 PHE A CG  1 
ATOM   593  C CD1 . PHE A 1 128 ? 172.107 175.334 223.282 1.00 59.63  ? 128 PHE A CD1 1 
ATOM   594  C CD2 . PHE A 1 128 ? 172.631 173.083 222.727 1.00 59.63  ? 128 PHE A CD2 1 
ATOM   595  C CE1 . PHE A 1 128 ? 172.854 175.774 222.214 1.00 59.63  ? 128 PHE A CE1 1 
ATOM   596  C CE2 . PHE A 1 128 ? 173.376 173.521 221.653 1.00 59.63  ? 128 PHE A CE2 1 
ATOM   597  C CZ  . PHE A 1 128 ? 173.489 174.866 221.399 1.00 59.63  ? 128 PHE A CZ  1 
ATOM   598  N N   . THR A 1 129 ? 171.492 175.586 227.046 1.00 60.32  ? 129 THR A N   1 
ATOM   599  C CA  . THR A 1 129 ? 171.845 176.932 227.492 1.00 60.32  ? 129 THR A CA  1 
ATOM   600  C C   . THR A 1 129 ? 172.854 176.895 228.636 1.00 60.32  ? 129 THR A C   1 
ATOM   601  O O   . THR A 1 129 ? 173.810 177.680 228.658 1.00 60.32  ? 129 THR A O   1 
ATOM   602  C CB  . THR A 1 129 ? 170.585 177.689 227.912 1.00 60.32  ? 129 THR A CB  1 
ATOM   603  O OG1 . THR A 1 129 ? 169.685 177.775 226.802 1.00 60.32  ? 129 THR A OG1 1 
ATOM   604  C CG2 . THR A 1 129 ? 170.933 179.089 228.376 1.00 60.32  ? 129 THR A CG2 1 
ATOM   605  N N   . ILE A 1 130 ? 172.660 175.989 229.597 1.00 61.49  ? 130 ILE A N   1 
ATOM   606  C CA  . ILE A 1 130 ? 173.581 175.894 230.727 1.00 61.49  ? 130 ILE A CA  1 
ATOM   607  C C   . ILE A 1 130 ? 174.972 175.486 230.255 1.00 61.49  ? 130 ILE A C   1 
ATOM   608  O O   . ILE A 1 130 ? 175.986 176.046 230.694 1.00 61.49  ? 130 ILE A O   1 
ATOM   609  C CB  . ILE A 1 130 ? 173.029 174.920 231.783 1.00 61.49  ? 130 ILE A CB  1 
ATOM   610  C CG1 . ILE A 1 130 ? 171.906 175.583 232.580 1.00 61.49  ? 130 ILE A CG1 1 
ATOM   611  C CG2 . ILE A 1 130 ? 174.132 174.449 232.713 1.00 61.49  ? 130 ILE A CG2 1 
ATOM   612  C CD1 . ILE A 1 130 ? 170.983 174.601 233.264 1.00 61.49  ? 130 ILE A CD1 1 
ATOM   613  N N   . SER A 1 131 ? 175.046 174.506 229.351 1.00 63.27  ? 131 SER A N   1 
ATOM   614  C CA  . SER A 1 131 ? 176.344 174.103 228.825 1.00 63.27  ? 131 SER A CA  1 
ATOM   615  C C   . SER A 1 131 ? 176.991 175.213 228.008 1.00 63.27  ? 131 SER A C   1 
ATOM   616  O O   . SER A 1 131 ? 178.217 175.358 228.030 1.00 63.27  ? 131 SER A O   1 
ATOM   617  C CB  . SER A 1 131 ? 176.201 172.836 227.989 1.00 63.27  ? 131 SER A CB  1 
ATOM   618  O OG  . SER A 1 131 ? 175.410 171.875 228.663 1.00 63.27  ? 131 SER A OG  1 
ATOM   619  N N   . SER A 1 132 ? 176.195 176.004 227.284 1.00 65.16  ? 132 SER A N   1 
ATOM   620  C CA  . SER A 1 132 ? 176.752 177.152 226.575 1.00 65.16  ? 132 SER A CA  1 
ATOM   621  C C   . SER A 1 132 ? 177.333 178.168 227.548 1.00 65.16  ? 132 SER A C   1 
ATOM   622  O O   . SER A 1 132 ? 178.381 178.765 227.279 1.00 65.16  ? 132 SER A O   1 
ATOM   623  C CB  . SER A 1 132 ? 175.684 177.801 225.698 1.00 65.16  ? 132 SER A CB  1 
ATOM   624  O OG  . SER A 1 132 ? 175.475 177.051 224.516 1.00 65.16  ? 132 SER A OG  1 
ATOM   625  N N   . VAL A 1 133 ? 176.659 178.386 228.680 1.00 67.29  ? 133 VAL A N   1 
ATOM   626  C CA  . VAL A 1 133 ? 177.211 179.263 229.712 1.00 67.29  ? 133 VAL A CA  1 
ATOM   627  C C   . VAL A 1 133 ? 178.539 178.719 230.218 1.00 67.29  ? 133 VAL A C   1 
ATOM   628  O O   . VAL A 1 133 ? 179.514 179.462 230.374 1.00 67.29  ? 133 VAL A O   1 
ATOM   629  C CB  . VAL A 1 133 ? 176.211 179.438 230.871 1.00 67.29  ? 133 VAL A CB  1 
ATOM   630  C CG1 . VAL A 1 133 ? 176.837 180.260 231.982 1.00 67.29  ? 133 VAL A CG1 1 
ATOM   631  C CG2 . VAL A 1 133 ? 174.944 180.098 230.389 1.00 67.29  ? 133 VAL A CG2 1 
ATOM   632  N N   . LEU A 1 134 ? 178.596 177.414 230.485 1.00 69.51  ? 134 LEU A N   1 
ATOM   633  C CA  . LEU A 1 134 ? 179.797 176.844 231.088 1.00 69.51  ? 134 LEU A CA  1 
ATOM   634  C C   . LEU A 1 134 ? 180.943 176.760 230.085 1.00 69.51  ? 134 LEU A C   1 
ATOM   635  O O   . LEU A 1 134 ? 182.110 176.705 230.486 1.00 69.51  ? 134 LEU A O   1 
ATOM   636  C CB  . LEU A 1 134 ? 179.475 175.471 231.683 1.00 69.51  ? 134 LEU A CB  1 
ATOM   637  C CG  . LEU A 1 134 ? 180.495 174.712 232.540 1.00 69.51  ? 134 LEU A CG  1 
ATOM   638  C CD1 . LEU A 1 134 ? 179.750 173.794 233.493 1.00 69.51  ? 134 LEU A CD1 1 
ATOM   639  C CD2 . LEU A 1 134 ? 181.477 173.901 231.718 1.00 69.51  ? 134 LEU A CD2 1 
ATOM   640  N N   . CYS A 1 135 ? 180.634 176.751 228.786 1.00 73.36  ? 135 CYS A N   1 
ATOM   641  C CA  . CYS A 1 135 ? 181.687 176.744 227.772 1.00 73.36  ? 135 CYS A CA  1 
ATOM   642  C C   . CYS A 1 135 ? 182.551 177.996 227.857 1.00 73.36  ? 135 CYS A C   1 
ATOM   643  O O   . CYS A 1 135 ? 183.778 177.921 227.730 1.00 73.36  ? 135 CYS A O   1 
ATOM   644  C CB  . CYS A 1 135 ? 181.079 176.627 226.373 1.00 73.36  ? 135 CYS A CB  1 
ATOM   645  S SG  . CYS A 1 135 ? 180.586 174.970 225.866 1.00 73.36  ? 135 CYS A SG  1 
ATOM   646  N N   . ALA A 1 136 ? 181.926 179.158 228.054 1.00 72.15  ? 136 ALA A N   1 
ATOM   647  C CA  . ALA A 1 136 ? 182.673 180.412 228.082 1.00 72.15  ? 136 ALA A CA  1 
ATOM   648  C C   . ALA A 1 136 ? 183.655 180.446 229.246 1.00 72.15  ? 136 ALA A C   1 
ATOM   649  O O   . ALA A 1 136 ? 184.813 180.845 229.084 1.00 72.15  ? 136 ALA A O   1 
ATOM   650  C CB  . ALA A 1 136 ? 181.707 181.592 228.157 1.00 72.15  ? 136 ALA A CB  1 
ATOM   651  N N   . VAL A 1 137 ? 183.212 180.033 230.429 1.00 73.70  ? 137 VAL A N   1 
ATOM   652  C CA  . VAL A 1 137 ? 184.084 180.026 231.616 1.00 73.70  ? 137 VAL A CA  1 
ATOM   653  C C   . VAL A 1 137 ? 184.749 178.654 231.660 1.00 73.70  ? 137 VAL A C   1 
ATOM   654  O O   . VAL A 1 137 ? 184.332 177.726 232.356 1.00 73.70  ? 137 VAL A O   1 
ATOM   655  C CB  . VAL A 1 137 ? 183.320 180.393 232.897 1.00 73.70  ? 137 VAL A CB  1 
ATOM   656  C CG1 . VAL A 1 137 ? 182.782 181.803 232.777 1.00 73.70  ? 137 VAL A CG1 1 
ATOM   657  C CG2 . VAL A 1 137 ? 182.139 179.462 233.131 1.00 73.70  ? 137 VAL A CG2 1 
ATOM   658  N N   . ALA A 1 138 ? 185.831 178.526 230.896 1.00 77.52  ? 138 ALA A N   1 
ATOM   659  C CA  . ALA A 1 138 ? 186.614 177.299 230.851 1.00 77.52  ? 138 ALA A CA  1 
ATOM   660  C C   . ALA A 1 138 ? 188.088 177.662 230.902 1.00 77.52  ? 138 ALA A C   1 
ATOM   661  O O   . ALA A 1 138 ? 188.524 178.581 230.203 1.00 77.52  ? 138 ALA A O   1 
ATOM   662  C CB  . ALA A 1 138 ? 186.309 176.485 229.590 1.00 77.52  ? 138 ALA A CB  1 
ATOM   663  N N   . TRP A 1 139 ? 188.850 176.945 231.725 1.00 81.79  ? 139 TRP A N   1 
ATOM   664  C CA  . TRP A 1 139 ? 190.262 177.250 231.925 1.00 81.79  ? 139 TRP A CA  1 
ATOM   665  C C   . TRP A 1 139 ? 191.195 176.309 231.178 1.00 81.79  ? 139 TRP A C   1 
ATOM   666  O O   . TRP A 1 139 ? 192.235 176.750 230.680 1.00 81.79  ? 139 TRP A O   1 
ATOM   667  C CB  . TRP A 1 139 ? 190.605 177.228 233.418 1.00 81.79  ? 139 TRP A CB  1 
ATOM   668  C CG  . TRP A 1 139 ? 189.970 176.108 234.176 1.00 81.79  ? 139 TRP A CG  1 
ATOM   669  C CD1 . TRP A 1 139 ? 190.526 174.898 234.467 1.00 81.79  ? 139 TRP A CD1 1 
ATOM   670  C CD2 . TRP A 1 139 ? 188.658 176.095 234.750 1.00 81.79  ? 139 TRP A CD2 1 
ATOM   671  N NE1 . TRP A 1 139 ? 189.641 174.130 235.183 1.00 81.79  ? 139 TRP A NE1 1 
ATOM   672  C CE2 . TRP A 1 139 ? 188.486 174.843 235.370 1.00 81.79  ? 139 TRP A CE2 1 
ATOM   673  C CE3 . TRP A 1 139 ? 187.611 177.020 234.798 1.00 81.79  ? 139 TRP A CE3 1 
ATOM   674  C CZ2 . TRP A 1 139 ? 187.311 174.492 236.029 1.00 81.79  ? 139 TRP A CZ2 1 
ATOM   675  C CZ3 . TRP A 1 139 ? 186.446 176.669 235.453 1.00 81.79  ? 139 TRP A CZ3 1 
ATOM   676  C CH2 . TRP A 1 139 ? 186.305 175.417 236.059 1.00 81.79  ? 139 TRP A CH2 1 
ATOM   677  N N   . ASP A 1 140 ? 190.857 175.024 231.083 1.00 83.30  ? 140 ASP A N   1 
ATOM   678  C CA  . ASP A 1 140 ? 191.721 174.078 230.388 1.00 83.30  ? 140 ASP A CA  1 
ATOM   679  C C   . ASP A 1 140 ? 190.933 173.236 229.393 1.00 83.30  ? 140 ASP A C   1 
ATOM   680  O O   . ASP A 1 140 ? 189.753 173.499 229.144 1.00 83.30  ? 140 ASP A O   1 
ATOM   681  C CB  . ASP A 1 140 ? 192.450 173.180 231.389 1.00 83.30  ? 140 ASP A CB  1 
ATOM   682  C CG  . ASP A 1 140 ? 191.508 172.292 232.170 1.00 83.30  ? 140 ASP A CG  1 
ATOM   683  O OD1 . ASP A 1 140 ? 190.347 172.697 232.383 1.00 83.30  ? 140 ASP A OD1 1 
ATOM   684  O OD2 . ASP A 1 140 ? 191.930 171.188 232.574 1.00 83.30  ? 140 ASP A OD2 1 
ATOM   685  N N   . GLU A 1 141 ? 191.584 172.224 228.818 1.00 84.27  ? 141 GLU A N   1 
ATOM   686  C CA  . GLU A 1 141 ? 190.950 171.428 227.771 1.00 84.27  ? 141 GLU A CA  1 
ATOM   687  C C   . GLU A 1 141 ? 189.813 170.573 228.320 1.00 84.27  ? 141 GLU A C   1 
ATOM   688  O O   . GLU A 1 141 ? 188.781 170.410 227.659 1.00 84.27  ? 141 GLU A O   1 
ATOM   689  C CB  . GLU A 1 141 ? 191.994 170.552 227.081 1.00 84.27  ? 141 GLU A CB  1 
ATOM   690  C CG  . GLU A 1 141 ? 191.484 169.832 225.846 1.00 84.27  ? 141 GLU A CG  1 
ATOM   691  C CD  . GLU A 1 141 ? 192.554 168.990 225.181 1.00 84.27  ? 141 GLU A CD  1 
ATOM   692  O OE1 . GLU A 1 141 ? 193.695 168.970 225.689 1.00 84.27  ? 141 GLU A OE1 1 
ATOM   693  O OE2 . GLU A 1 141 ? 192.257 168.349 224.151 1.00 84.27  ? 141 GLU A OE2 1 
ATOM   694  N N   . ALA A 1 142 ? 189.987 170.012 229.519 1.00 80.22  ? 142 ALA A N   1 
ATOM   695  C CA  . ALA A 1 142 ? 189.005 169.069 230.049 1.00 80.22  ? 142 ALA A CA  1 
ATOM   696  C C   . ALA A 1 142 ? 187.650 169.730 230.270 1.00 80.22  ? 142 ALA A C   1 
ATOM   697  O O   . ALA A 1 142 ? 186.606 169.144 229.955 1.00 80.22  ? 142 ALA A O   1 
ATOM   698  C CB  . ALA A 1 142 ? 189.520 168.456 231.350 1.00 80.22  ? 142 ALA A CB  1 
ATOM   699  N N   . THR A 1 143 ? 187.645 170.944 230.826 1.00 77.06  ? 143 THR A N   1 
ATOM   700  C CA  . THR A 1 143 ? 186.384 171.639 231.063 1.00 77.06  ? 143 THR A CA  1 
ATOM   701  C C   . THR A 1 143 ? 185.668 171.943 229.755 1.00 77.06  ? 143 THR A C   1 
ATOM   702  O O   . THR A 1 143 ? 184.450 171.764 229.650 1.00 77.06  ? 143 THR A O   1 
ATOM   703  C CB  . THR A 1 143 ? 186.631 172.923 231.851 1.00 77.06  ? 143 THR A CB  1 
ATOM   704  O OG1 . THR A 1 143 ? 187.574 172.667 232.897 1.00 77.06  ? 143 THR A OG1 1 
ATOM   705  C CG2 . THR A 1 143 ? 185.334 173.425 232.460 1.00 77.06  ? 143 THR A CG2 1 
ATOM   706  N N   . LEU A 1 144 ? 186.410 172.392 228.741 1.00 74.55  ? 144 LEU A N   1 
ATOM   707  C CA  . LEU A 1 144 ? 185.798 172.653 227.443 1.00 74.55  ? 144 LEU A CA  1 
ATOM   708  C C   . LEU A 1 144 ? 185.236 171.377 226.833 1.00 74.55  ? 144 LEU A C   1 
ATOM   709  O O   . LEU A 1 144 ? 184.145 171.387 226.251 1.00 74.55  ? 144 LEU A O   1 
ATOM   710  C CB  . LEU A 1 144 ? 186.817 173.295 226.502 1.00 74.55  ? 144 LEU A CB  1 
ATOM   711  C CG  . LEU A 1 144 ? 186.248 173.955 225.245 1.00 74.55  ? 144 LEU A CG  1 
ATOM   712  C CD1 . LEU A 1 144 ? 185.381 175.145 225.611 1.00 74.55  ? 144 LEU A CD1 1 
ATOM   713  C CD2 . LEU A 1 144 ? 187.365 174.376 224.310 1.00 74.55  ? 144 LEU A CD2 1 
ATOM   714  N N   . VAL A 1 145 ? 185.962 170.265 226.958 1.00 72.30  ? 145 VAL A N   1 
ATOM   715  C CA  . VAL A 1 145 ? 185.505 169.010 226.369 1.00 72.30  ? 145 VAL A CA  1 
ATOM   716  C C   . VAL A 1 145 ? 184.224 168.533 227.044 1.00 72.30  ? 145 VAL A C   1 
ATOM   717  O O   . VAL A 1 145 ? 183.264 168.132 226.374 1.00 72.30  ? 145 VAL A O   1 
ATOM   718  C CB  . VAL A 1 145 ? 186.615 167.948 226.442 1.00 72.30  ? 145 VAL A CB  1 
ATOM   719  C CG1 . VAL A 1 145 ? 186.045 166.565 226.180 1.00 72.30  ? 145 VAL A CG1 1 
ATOM   720  C CG2 . VAL A 1 145 ? 187.713 168.267 225.443 1.00 72.30  ? 145 VAL A CG2 1 
ATOM   721  N N   . ILE A 1 146 ? 184.182 168.573 228.379 1.00 70.30  ? 146 ILE A N   1 
ATOM   722  C CA  . ILE A 1 146 ? 182.972 168.119 229.063 1.00 70.30  ? 146 ILE A CA  1 
ATOM   723  C C   . ILE A 1 146 ? 181.813 169.075 228.803 1.00 70.30  ? 146 ILE A C   1 
ATOM   724  O O   . ILE A 1 146 ? 180.654 168.644 228.720 1.00 70.30  ? 146 ILE A O   1 
ATOM   725  C CB  . ILE A 1 146 ? 183.223 167.916 230.570 1.00 70.30  ? 146 ILE A CB  1 
ATOM   726  C CG1 . ILE A 1 146 ? 183.503 169.242 231.275 1.00 70.30  ? 146 ILE A CG1 1 
ATOM   727  C CG2 . ILE A 1 146 ? 184.366 166.940 230.793 1.00 70.30  ? 146 ILE A CG2 1 
ATOM   728  C CD1 . ILE A 1 146 ? 183.531 169.132 232.781 1.00 70.30  ? 146 ILE A CD1 1 
ATOM   729  N N   . ALA A 1 147 ? 182.090 170.373 228.657 1.00 67.70  ? 147 ALA A N   1 
ATOM   730  C CA  . ALA A 1 147 ? 181.031 171.312 228.304 1.00 67.70  ? 147 ALA A CA  1 
ATOM   731  C C   . ALA A 1 147 ? 180.463 171.012 226.924 1.00 67.70  ? 147 ALA A C   1 
ATOM   732  O O   . ALA A 1 147 ? 179.243 171.053 226.727 1.00 67.70  ? 147 ALA A O   1 
ATOM   733  C CB  . ALA A 1 147 ? 181.560 172.741 228.367 1.00 67.70  ? 147 ALA A CB  1 
ATOM   734  N N   . ARG A 1 148 ? 181.331 170.708 225.957 1.00 65.85  ? 148 ARG A N   1 
ATOM   735  C CA  . ARG A 1 148 ? 180.853 170.342 224.628 1.00 65.85  ? 148 ARG A CA  1 
ATOM   736  C C   . ARG A 1 148 ? 180.039 169.055 224.672 1.00 65.85  ? 148 ARG A C   1 
ATOM   737  O O   . ARG A 1 148 ? 179.023 168.932 223.978 1.00 65.85  ? 148 ARG A O   1 
ATOM   738  C CB  . ARG A 1 148 ? 182.028 170.203 223.660 1.00 65.85  ? 148 ARG A CB  1 
ATOM   739  C CG  . ARG A 1 148 ? 182.784 171.495 223.403 1.00 65.85  ? 148 ARG A CG  1 
ATOM   740  C CD  . ARG A 1 148 ? 181.945 172.495 222.627 1.00 65.85  ? 148 ARG A CD  1 
ATOM   741  N NE  . ARG A 1 148 ? 181.905 172.192 221.203 1.00 65.85  ? 148 ARG A NE  1 
ATOM   742  C CZ  . ARG A 1 148 ? 181.028 172.710 220.354 1.00 65.85  ? 148 ARG A CZ  1 
ATOM   743  N NH1 . ARG A 1 148 ? 180.099 173.561 220.754 1.00 65.85  ? 148 ARG A NH1 1 
ATOM   744  N NH2 . ARG A 1 148 ? 181.085 172.364 219.072 1.00 65.85  ? 148 ARG A NH2 1 
ATOM   745  N N   . LEU A 1 149 ? 180.467 168.083 225.482 1.00 65.30  ? 149 LEU A N   1 
ATOM   746  C CA  . LEU A 1 149 ? 179.703 166.844 225.610 1.00 65.30  ? 149 LEU A CA  1 
ATOM   747  C C   . LEU A 1 149 ? 178.314 167.105 226.181 1.00 65.30  ? 149 LEU A C   1 
ATOM   748  O O   . LEU A 1 149 ? 177.316 166.580 225.672 1.00 65.30  ? 149 LEU A O   1 
ATOM   749  C CB  . LEU A 1 149 ? 180.456 165.843 226.486 1.00 65.30  ? 149 LEU A CB  1 
ATOM   750  C CG  . LEU A 1 149 ? 181.767 165.257 225.961 1.00 65.30  ? 149 LEU A CG  1 
ATOM   751  C CD1 . LEU A 1 149 ? 182.496 164.524 227.071 1.00 65.30  ? 149 LEU A CD1 1 
ATOM   752  C CD2 . LEU A 1 149 ? 181.525 164.333 224.786 1.00 65.30  ? 149 LEU A CD2 1 
ATOM   753  N N   . SER A 1 150 ? 178.226 167.917 227.237 1.00 62.93  ? 150 SER A N   1 
ATOM   754  C CA  . SER A 1 150 ? 176.925 168.220 227.827 1.00 62.93  ? 150 SER A CA  1 
ATOM   755  C C   . SER A 1 150 ? 176.041 168.987 226.852 1.00 62.93  ? 150 SER A C   1 
ATOM   756  O O   . SER A 1 150 ? 174.827 168.749 226.772 1.00 62.93  ? 150 SER A O   1 
ATOM   757  C CB  . SER A 1 150 ? 177.110 169.013 229.119 1.00 62.93  ? 150 SER A CB  1 
ATOM   758  O OG  . SER A 1 150 ? 178.005 168.353 229.993 1.00 62.93  ? 150 SER A OG  1 
ATOM   759  N N   . GLN A 1 151 ? 176.633 169.919 226.106 1.00 63.11  ? 151 GLN A N   1 
ATOM   760  C CA  . GLN A 1 151 ? 175.877 170.685 225.125 1.00 63.11  ? 151 GLN A CA  1 
ATOM   761  C C   . GLN A 1 151 ? 175.338 169.779 224.026 1.00 63.11  ? 151 GLN A C   1 
ATOM   762  O O   . GLN A 1 151 ? 174.190 169.929 223.590 1.00 63.11  ? 151 GLN A O   1 
ATOM   763  C CB  . GLN A 1 151 ? 176.774 171.782 224.558 1.00 63.11  ? 151 GLN A CB  1 
ATOM   764  C CG  . GLN A 1 151 ? 176.098 172.783 223.669 1.00 63.11  ? 151 GLN A CG  1 
ATOM   765  C CD  . GLN A 1 151 ? 177.039 173.892 223.261 1.00 63.11  ? 151 GLN A CD  1 
ATOM   766  O OE1 . GLN A 1 151 ? 178.221 173.869 223.595 1.00 63.11  ? 151 GLN A OE1 1 
ATOM   767  N NE2 . GLN A 1 151 ? 176.516 174.881 222.557 1.00 63.11  ? 151 GLN A NE2 1 
ATOM   768  N N   . GLY A 1 152 ? 176.149 168.818 223.580 1.00 62.33  ? 152 GLY A N   1 
ATOM   769  C CA  . GLY A 1 152 ? 175.674 167.850 222.607 1.00 62.33  ? 152 GLY A CA  1 
ATOM   770  C C   . GLY A 1 152 ? 174.574 166.961 223.151 1.00 62.33  ? 152 GLY A C   1 
ATOM   771  O O   . GLY A 1 152 ? 173.648 166.595 222.428 1.00 62.33  ? 152 GLY A O   1 
ATOM   772  N N   . VAL A 1 153 ? 174.662 166.594 224.431 1.00 60.89  ? 153 VAL A N   1 
ATOM   773  C CA  . VAL A 1 153 ? 173.602 165.794 225.047 1.00 60.89  ? 153 VAL A CA  1 
ATOM   774  C C   . VAL A 1 153 ? 172.288 166.568 225.051 1.00 60.89  ? 153 VAL A C   1 
ATOM   775  O O   . VAL A 1 153 ? 171.225 166.031 224.712 1.00 60.89  ? 153 VAL A O   1 
ATOM   776  C CB  . VAL A 1 153 ? 174.006 165.365 226.469 1.00 60.89  ? 153 VAL A CB  1 
ATOM   777  C CG1 . VAL A 1 153 ? 172.804 164.827 227.220 1.00 60.89  ? 153 VAL A CG1 1 
ATOM   778  C CG2 . VAL A 1 153 ? 175.105 164.322 226.418 1.00 60.89  ? 153 VAL A CG2 1 
ATOM   779  N N   . GLY A 1 154 ? 172.343 167.843 225.436 1.00 59.17  ? 154 GLY A N   1 
ATOM   780  C CA  . GLY A 1 154 ? 171.140 168.661 225.410 1.00 59.17  ? 154 GLY A CA  1 
ATOM   781  C C   . GLY A 1 154 ? 170.575 168.823 224.012 1.00 59.17  ? 154 GLY A C   1 
ATOM   782  O O   . GLY A 1 154 ? 169.358 168.758 223.808 1.00 59.17  ? 154 GLY A O   1 
ATOM   783  N N   . SER A 1 155 ? 171.453 169.028 223.027 1.00 59.72  ? 155 SER A N   1 
ATOM   784  C CA  . SER A 1 155 ? 171.000 169.138 221.645 1.00 59.72  ? 155 SER A CA  1 
ATOM   785  C C   . SER A 1 155 ? 170.347 167.847 221.170 1.00 59.72  ? 155 SER A C   1 
ATOM   786  O O   . SER A 1 155 ? 169.328 167.881 220.475 1.00 59.72  ? 155 SER A O   1 
ATOM   787  C CB  . SER A 1 155 ? 172.170 169.507 220.737 1.00 59.72  ? 155 SER A CB  1 
ATOM   788  O OG  . SER A 1 155 ? 171.753 169.597 219.389 1.00 59.72  ? 155 SER A OG  1 
ATOM   789  N N   . ALA A 1 156 ? 170.923 166.698 221.526 1.00 61.12  ? 156 ALA A N   1 
ATOM   790  C CA  . ALA A 1 156 ? 170.345 165.421 221.126 1.00 61.12  ? 156 ALA A CA  1 
ATOM   791  C C   . ALA A 1 156 ? 169.004 165.175 221.799 1.00 61.12  ? 156 ALA A C   1 
ATOM   792  O O   . ALA A 1 156 ? 168.126 164.539 221.210 1.00 61.12  ? 156 ALA A O   1 
ATOM   793  C CB  . ALA A 1 156 ? 171.309 164.282 221.445 1.00 61.12  ? 156 ALA A CB  1 
ATOM   794  N N   . ILE A 1 157 ? 168.833 165.651 223.031 1.00 59.89  ? 157 ILE A N   1 
ATOM   795  C CA  . ILE A 1 157 ? 167.539 165.512 223.693 1.00 59.89  ? 157 ILE A CA  1 
ATOM   796  C C   . ILE A 1 157 ? 166.493 166.396 223.024 1.00 59.89  ? 157 ILE A C   1 
ATOM   797  O O   . ILE A 1 157 ? 165.347 165.978 222.821 1.00 59.89  ? 157 ILE A O   1 
ATOM   798  C CB  . ILE A 1 157 ? 167.667 165.824 225.195 1.00 59.89  ? 157 ILE A CB  1 
ATOM   799  C CG1 . ILE A 1 157 ? 168.243 164.624 225.944 1.00 59.89  ? 157 ILE A CG1 1 
ATOM   800  C CG2 . ILE A 1 157 ? 166.323 166.199 225.784 1.00 59.89  ? 157 ILE A CG2 1 
ATOM   801  C CD1 . ILE A 1 157 ? 168.593 164.923 227.382 1.00 59.89  ? 157 ILE A CD1 1 
ATOM   802  N N   . ALA A 1 158 ? 166.866 167.623 222.656 1.00 58.98  ? 158 ALA A N   1 
ATOM   803  C CA  . ALA A 1 158 ? 165.864 168.597 222.235 1.00 58.98  ? 158 ALA A CA  1 
ATOM   804  C C   . ALA A 1 158 ? 165.567 168.593 220.738 1.00 58.98  ? 158 ALA A C   1 
ATOM   805  O O   . ALA A 1 158 ? 164.437 168.908 220.350 1.00 58.98  ? 158 ALA A O   1 
ATOM   806  C CB  . ALA A 1 158 ? 166.294 170.004 222.652 1.00 58.98  ? 158 ALA A CB  1 
ATOM   807  N N   . SER A 1 159 ? 166.539 168.268 219.884 1.00 59.87  ? 159 SER A N   1 
ATOM   808  C CA  . SER A 1 159 ? 166.345 168.426 218.443 1.00 59.87  ? 159 SER A CA  1 
ATOM   809  C C   . SER A 1 159 ? 165.270 167.518 217.857 1.00 59.87  ? 159 SER A C   1 
ATOM   810  O O   . SER A 1 159 ? 164.395 168.029 217.139 1.00 59.87  ? 159 SER A O   1 
ATOM   811  C CB  . SER A 1 159 ? 167.683 168.232 217.722 1.00 59.87  ? 159 SER A CB  1 
ATOM   812  O OG  . SER A 1 159 ? 168.515 169.366 217.875 1.00 59.87  ? 159 SER A OG  1 
ATOM   813  N N   . PRO A 1 160 ? 165.270 166.196 218.085 1.00 56.94  ? 160 PRO A N   1 
ATOM   814  C CA  . PRO A 1 160 ? 164.234 165.357 217.460 1.00 56.94  ? 160 PRO A CA  1 
ATOM   815  C C   . PRO A 1 160 ? 162.830 165.647 217.954 1.00 56.94  ? 160 PRO A C   1 
ATOM   816  O O   . PRO A 1 160 ? 161.867 165.273 217.276 1.00 56.94  ? 160 PRO A O   1 
ATOM   817  C CB  . PRO A 1 160 ? 164.668 163.932 217.826 1.00 56.94  ? 160 PRO A CB  1 
ATOM   818  C CG  . PRO A 1 160 ? 165.466 164.092 219.049 1.00 56.94  ? 160 PRO A CG  1 
ATOM   819  C CD  . PRO A 1 160 ? 166.207 165.377 218.873 1.00 56.94  ? 160 PRO A CD  1 
ATOM   820  N N   . THR A 1 161 ? 162.681 166.289 219.112 1.00 56.34  ? 161 THR A N   1 
ATOM   821  C CA  . THR A 1 161 ? 161.363 166.618 219.634 1.00 56.34  ? 161 THR A CA  1 
ATOM   822  C C   . THR A 1 161 ? 160.719 167.784 218.894 1.00 56.34  ? 161 THR A C   1 
ATOM   823  O O   . THR A 1 161 ? 159.491 167.896 218.893 1.00 56.34  ? 161 THR A O   1 
ATOM   824  C CB  . THR A 1 161 ? 161.461 166.927 221.131 1.00 56.34  ? 161 THR A CB  1 
ATOM   825  O OG1 . THR A 1 161 ? 162.168 165.869 221.786 1.00 56.34  ? 161 THR A OG1 1 
ATOM   826  C CG2 . THR A 1 161 ? 160.086 167.035 221.755 1.00 56.34  ? 161 THR A CG2 1 
ATOM   827  N N   . GLY A 1 162 ? 161.510 168.640 218.246 1.00 54.03  ? 162 GLY A N   1 
ATOM   828  C CA  . GLY A 1 162 ? 160.930 169.753 217.510 1.00 54.03  ? 162 GLY A CA  1 
ATOM   829  C C   . GLY A 1 162 ? 160.085 169.305 216.331 1.00 54.03  ? 162 GLY A C   1 
ATOM   830  O O   . GLY A 1 162 ? 158.983 169.815 216.112 1.00 54.03  ? 162 GLY A O   1 
ATOM   831  N N   . LEU A 1 163 ? 160.590 168.347 215.552 1.00 54.25  ? 163 LEU A N   1 
ATOM   832  C CA  . LEU A 1 163 ? 159.819 167.833 214.423 1.00 54.25  ? 163 LEU A CA  1 
ATOM   833  C C   . LEU A 1 163 ? 158.566 167.106 214.897 1.00 54.25  ? 163 LEU A C   1 
ATOM   834  O O   . LEU A 1 163 ? 157.500 167.218 214.277 1.00 54.25  ? 163 LEU A O   1 
ATOM   835  C CB  . LEU A 1 163 ? 160.691 166.914 213.571 1.00 54.25  ? 163 LEU A CB  1 
ATOM   836  C CG  . LEU A 1 163 ? 160.262 166.717 212.116 1.00 54.25  ? 163 LEU A CG  1 
ATOM   837  C CD1 . LEU A 1 163 ? 159.941 168.046 211.460 1.00 54.25  ? 163 LEU A CD1 1 
ATOM   838  C CD2 . LEU A 1 163 ? 161.336 165.982 211.335 1.00 54.25  ? 163 LEU A CD2 1 
ATOM   839  N N   . ALA A 1 164 ? 158.674 166.356 215.994 1.00 54.26  ? 164 ALA A N   1 
ATOM   840  C CA  . ALA A 1 164 ? 157.503 165.695 216.555 1.00 54.26  ? 164 ALA A CA  1 
ATOM   841  C C   . ALA A 1 164 ? 156.470 166.711 217.020 1.00 54.26  ? 164 ALA A C   1 
ATOM   842  O O   . ALA A 1 164 ? 155.265 166.492 216.869 1.00 54.26  ? 164 ALA A O   1 
ATOM   843  C CB  . ALA A 1 164 ? 157.917 164.783 217.707 1.00 54.26  ? 164 ALA A CB  1 
ATOM   844  N N   . LEU A 1 165 ? 156.922 167.825 217.597 1.00 54.64  ? 165 LEU A N   1 
ATOM   845  C CA  . LEU A 1 165 ? 155.991 168.869 218.014 1.00 54.64  ? 165 LEU A CA  1 
ATOM   846  C C   . LEU A 1 165 ? 155.348 169.545 216.811 1.00 54.64  ? 165 LEU A C   1 
ATOM   847  O O   . LEU A 1 165 ? 154.176 169.928 216.866 1.00 54.64  ? 165 LEU A O   1 
ATOM   848  C CB  . LEU A 1 165 ? 156.707 169.892 218.891 1.00 54.64  ? 165 LEU A CB  1 
ATOM   849  C CG  . LEU A 1 165 ? 156.883 169.498 220.357 1.00 54.64  ? 165 LEU A CG  1 
ATOM   850  C CD1 . LEU A 1 165 ? 157.729 170.520 221.084 1.00 54.64  ? 165 LEU A CD1 1 
ATOM   851  C CD2 . LEU A 1 165 ? 155.534 169.343 221.029 1.00 54.64  ? 165 LEU A CD2 1 
ATOM   852  N N   . VAL A 1 166 ? 156.097 169.703 215.718 1.00 53.42  ? 166 VAL A N   1 
ATOM   853  C CA  . VAL A 1 166 ? 155.501 170.206 214.481 1.00 53.42  ? 166 VAL A CA  1 
ATOM   854  C C   . VAL A 1 166 ? 154.396 169.273 214.011 1.00 53.42  ? 166 VAL A C   1 
ATOM   855  O O   . VAL A 1 166 ? 153.307 169.716 213.628 1.00 53.42  ? 166 VAL A O   1 
ATOM   856  C CB  . VAL A 1 166 ? 156.575 170.385 213.392 1.00 53.42  ? 166 VAL A CB  1 
ATOM   857  C CG1 . VAL A 1 166 ? 155.924 170.579 212.039 1.00 53.42  ? 166 VAL A CG1 1 
ATOM   858  C CG2 . VAL A 1 166 ? 157.456 171.565 213.706 1.00 53.42  ? 166 VAL A CG2 1 
ATOM   859  N N   . ALA A 1 167 ? 154.658 167.967 214.034 1.00 56.30  ? 167 ALA A N   1 
ATOM   860  C CA  . ALA A 1 167 ? 153.673 167.008 213.545 1.00 56.30  ? 167 ALA A CA  1 
ATOM   861  C C   . ALA A 1 167 ? 152.451 166.930 214.455 1.00 56.30  ? 167 ALA A C   1 
ATOM   862  O O   . ALA A 1 167 ? 151.320 166.813 213.971 1.00 56.30  ? 167 ALA A O   1 
ATOM   863  C CB  . ALA A 1 167 ? 154.314 165.632 213.391 1.00 56.30  ? 167 ALA A CB  1 
ATOM   864  N N   . THR A 1 168 ? 152.651 166.989 215.772 1.00 59.23  ? 168 THR A N   1 
ATOM   865  C CA  . THR A 1 168 ? 151.587 166.726 216.733 1.00 59.23  ? 168 THR A CA  1 
ATOM   866  C C   . THR A 1 168 ? 150.971 167.983 217.335 1.00 59.23  ? 168 THR A C   1 
ATOM   867  O O   . THR A 1 168 ? 150.103 167.867 218.205 1.00 59.23  ? 168 THR A O   1 
ATOM   868  C CB  . THR A 1 168 ? 152.108 165.834 217.863 1.00 59.23  ? 168 THR A CB  1 
ATOM   869  O OG1 . THR A 1 168 ? 153.121 166.531 218.595 1.00 59.23  ? 168 THR A OG1 1 
ATOM   870  C CG2 . THR A 1 168 ? 152.691 164.552 217.303 1.00 59.23  ? 168 THR A CG2 1 
ATOM   871  N N   . THR A 1 169 ? 151.389 169.172 216.910 1.00 59.28  ? 169 THR A N   1 
ATOM   872  C CA  . THR A 1 169 ? 150.809 170.412 217.412 1.00 59.28  ? 169 THR A CA  1 
ATOM   873  C C   . THR A 1 169 ? 149.801 171.021 216.450 1.00 59.28  ? 169 THR A C   1 
ATOM   874  O O   . THR A 1 169 ? 148.717 171.433 216.873 1.00 59.28  ? 169 THR A O   1 
ATOM   875  C CB  . THR A 1 169 ? 151.913 171.434 217.705 1.00 59.28  ? 169 THR A CB  1 
ATOM   876  O OG1 . THR A 1 169 ? 152.693 170.990 218.820 1.00 59.28  ? 169 THR A OG1 1 
ATOM   877  C CG2 . THR A 1 169 ? 151.316 172.789 218.031 1.00 59.28  ? 169 THR A CG2 1 
ATOM   878  N N   . PHE A 1 170 ? 150.132 171.077 215.164 1.00 61.75  ? 170 PHE A N   1 
ATOM   879  C CA  . PHE A 1 170 ? 149.253 171.616 214.144 1.00 61.75  ? 170 PHE A CA  1 
ATOM   880  C C   . PHE A 1 170 ? 148.654 170.486 213.327 1.00 61.75  ? 170 PHE A C   1 
ATOM   881  O O   . PHE A 1 170 ? 149.399 169.635 212.824 1.00 61.75  ? 170 PHE A O   1 
ATOM   882  C CB  . PHE A 1 170 ? 150.018 172.572 213.229 1.00 61.75  ? 170 PHE A CB  1 
ATOM   883  C CG  . PHE A 1 170 ? 150.778 173.632 213.966 1.00 61.75  ? 170 PHE A CG  1 
ATOM   884  C CD1 . PHE A 1 170 ? 150.125 174.729 214.496 1.00 61.75  ? 170 PHE A CD1 1 
ATOM   885  C CD2 . PHE A 1 170 ? 152.145 173.527 214.137 1.00 61.75  ? 170 PHE A CD2 1 
ATOM   886  C CE1 . PHE A 1 170 ? 150.821 175.704 215.175 1.00 61.75  ? 170 PHE A CE1 1 
ATOM   887  C CE2 . PHE A 1 170 ? 152.847 174.499 214.816 1.00 61.75  ? 170 PHE A CE2 1 
ATOM   888  C CZ  . PHE A 1 170 ? 152.183 175.589 215.336 1.00 61.75  ? 170 PHE A CZ  1 
ATOM   889  N N   . PRO A 1 171 ? 147.334 170.433 213.179 1.00 65.05  ? 171 PRO A N   1 
ATOM   890  C CA  . PRO A 1 171 ? 146.725 169.377 212.367 1.00 65.05  ? 171 PRO A CA  1 
ATOM   891  C C   . PRO A 1 171 ? 147.115 169.515 210.905 1.00 65.05  ? 171 PRO A C   1 
ATOM   892  O O   . PRO A 1 171 ? 147.503 170.585 210.432 1.00 65.05  ? 171 PRO A O   1 
ATOM   893  C CB  . PRO A 1 171 ? 145.219 169.595 212.560 1.00 65.05  ? 171 PRO A CB  1 
ATOM   894  C CG  . PRO A 1 171 ? 145.097 170.494 213.750 1.00 65.05  ? 171 PRO A CG  1 
ATOM   895  C CD  . PRO A 1 171 ? 146.326 171.335 213.756 1.00 65.05  ? 171 PRO A CD  1 
ATOM   896  N N   . LYS A 1 172 ? 147.021 168.396 210.191 1.00 64.50  ? 172 LYS A N   1 
ATOM   897  C CA  . LYS A 1 172 ? 147.374 168.377 208.778 1.00 64.50  ? 172 LYS A CA  1 
ATOM   898  C C   . LYS A 1 172 ? 146.526 169.378 208.004 1.00 64.50  ? 172 LYS A C   1 
ATOM   899  O O   . LYS A 1 172 ? 145.306 169.444 208.179 1.00 64.50  ? 172 LYS A O   1 
ATOM   900  C CB  . LYS A 1 172 ? 147.188 166.971 208.212 1.00 64.50  ? 172 LYS A CB  1 
ATOM   901  C CG  . LYS A 1 172 ? 147.879 166.743 206.885 1.00 64.50  ? 172 LYS A CG  1 
ATOM   902  C CD  . LYS A 1 172 ? 147.884 165.273 206.520 1.00 64.50  ? 172 LYS A CD  1 
ATOM   903  C CE  . LYS A 1 172 ? 146.480 164.780 206.233 1.00 64.50  ? 172 LYS A CE  1 
ATOM   904  N NZ  . LYS A 1 172 ? 146.475 163.407 205.670 1.00 64.50  ? 172 LYS A NZ  1 
ATOM   905  N N   . GLY A 1 173 ? 147.179 170.165 207.155 1.00 63.01  ? 173 GLY A N   1 
ATOM   906  C CA  . GLY A 1 173 ? 146.517 171.214 206.418 1.00 63.01  ? 173 GLY A CA  1 
ATOM   907  C C   . GLY A 1 173 ? 147.413 172.422 206.245 1.00 63.01  ? 173 GLY A C   1 
ATOM   908  O O   . GLY A 1 173 ? 148.641 172.316 206.270 1.00 63.01  ? 173 GLY A O   1 
ATOM   909  N N   . PRO A 1 174 ? 146.813 173.599 206.055 1.00 60.66  ? 174 PRO A N   1 
ATOM   910  C CA  . PRO A 1 174 ? 147.627 174.818 205.900 1.00 60.66  ? 174 PRO A CA  1 
ATOM   911  C C   . PRO A 1 174 ? 148.492 175.139 207.108 1.00 60.66  ? 174 PRO A C   1 
ATOM   912  O O   . PRO A 1 174 ? 149.606 175.658 206.944 1.00 60.66  ? 174 PRO A O   1 
ATOM   913  C CB  . PRO A 1 174 ? 146.575 175.910 205.655 1.00 60.66  ? 174 PRO A CB  1 
ATOM   914  C CG  . PRO A 1 174 ? 145.351 175.177 205.200 1.00 60.66  ? 174 PRO A CG  1 
ATOM   915  C CD  . PRO A 1 174 ? 145.373 173.870 205.917 1.00 60.66  ? 174 PRO A CD  1 
ATOM   916  N N   . ALA A 1 175 ? 148.009 174.848 208.318 1.00 60.21  ? 175 ALA A N   1 
ATOM   917  C CA  . ALA A 1 175 ? 148.771 175.168 209.521 1.00 60.21  ? 175 ALA A CA  1 
ATOM   918  C C   . ALA A 1 175 ? 150.083 174.397 209.561 1.00 60.21  ? 175 ALA A C   1 
ATOM   919  O O   . ALA A 1 175 ? 151.141 174.963 209.865 1.00 60.21  ? 175 ALA A O   1 
ATOM   920  C CB  . ALA A 1 175 ? 147.934 174.873 210.764 1.00 60.21  ? 175 ALA A CB  1 
ATOM   921  N N   . ARG A 1 176 ? 150.036 173.100 209.250 1.00 58.95  ? 176 ARG A N   1 
ATOM   922  C CA  . ARG A 1 176 ? 151.262 172.314 209.235 1.00 58.95  ? 176 ARG A CA  1 
ATOM   923  C C   . ARG A 1 176 ? 152.197 172.758 208.121 1.00 58.95  ? 176 ARG A C   1 
ATOM   924  O O   . ARG A 1 176 ? 153.417 172.708 208.291 1.00 58.95  ? 176 ARG A O   1 
ATOM   925  C CB  . ARG A 1 176 ? 150.949 170.826 209.099 1.00 58.95  ? 176 ARG A CB  1 
ATOM   926  C CG  . ARG A 1 176 ? 152.117 169.933 209.476 1.00 58.95  ? 176 ARG A CG  1 
ATOM   927  C CD  . ARG A 1 176 ? 151.852 168.483 209.132 1.00 58.95  ? 176 ARG A CD  1 
ATOM   928  N NE  . ARG A 1 176 ? 151.145 167.789 210.199 1.00 58.95  ? 176 ARG A NE  1 
ATOM   929  C CZ  . ARG A 1 176 ? 150.917 166.484 210.217 1.00 58.95  ? 176 ARG A CZ  1 
ATOM   930  N NH1 . ARG A 1 176 ? 151.332 165.697 209.239 1.00 58.95  ? 176 ARG A NH1 1 
ATOM   931  N NH2 . ARG A 1 176 ? 150.257 165.955 211.242 1.00 58.95  ? 176 ARG A NH2 1 
ATOM   932  N N   . ASN A 1 177 ? 151.654 173.199 206.985 1.00 58.18  ? 177 ASN A N   1 
ATOM   933  C CA  . ASN A 1 177 ? 152.502 173.711 205.913 1.00 58.18  ? 177 ASN A CA  1 
ATOM   934  C C   . ASN A 1 177 ? 153.257 174.958 206.360 1.00 58.18  ? 177 ASN A C   1 
ATOM   935  O O   . ASN A 1 177 ? 154.467 175.086 206.130 1.00 58.18  ? 177 ASN A O   1 
ATOM   936  C CB  . ASN A 1 177 ? 151.657 174.006 204.675 1.00 58.18  ? 177 ASN A CB  1 
ATOM   937  C CG  . ASN A 1 177 ? 150.865 172.804 204.214 1.00 58.18  ? 177 ASN A CG  1 
ATOM   938  O OD1 . ASN A 1 177 ? 150.928 171.738 204.820 1.00 58.18  ? 177 ASN A OD1 1 
ATOM   939  N ND2 . ASN A 1 177 ? 150.115 172.969 203.133 1.00 58.18  ? 177 ASN A ND2 1 
ATOM   940  N N   . ALA A 1 178 ? 152.558 175.888 207.016 1.00 56.32  ? 178 ALA A N   1 
ATOM   941  C CA  . ALA A 1 178 ? 153.224 177.088 207.512 1.00 56.32  ? 178 ALA A CA  1 
ATOM   942  C C   . ALA A 1 178 ? 154.259 176.749 208.580 1.00 56.32  ? 178 ALA A C   1 
ATOM   943  O O   . ALA A 1 178 ? 155.362 177.314 208.594 1.00 56.32  ? 178 ALA A O   1 
ATOM   944  C CB  . ALA A 1 178 ? 152.191 178.073 208.055 1.00 56.32  ? 178 ALA A CB  1 
ATOM   945  N N   . ALA A 1 179 ? 153.919 175.827 209.486 1.00 54.91  ? 179 ALA A N   1 
ATOM   946  C CA  . ALA A 1 179 ? 154.863 175.432 210.527 1.00 54.91  ? 179 ALA A CA  1 
ATOM   947  C C   . ALA A 1 179 ? 156.105 174.788 209.928 1.00 54.91  ? 179 ALA A C   1 
ATOM   948  O O   . ALA A 1 179 ? 157.226 175.048 210.378 1.00 54.91  ? 179 ALA A O   1 
ATOM   949  C CB  . ALA A 1 179 ? 154.189 174.480 211.510 1.00 54.91  ? 179 ALA A CB  1 
ATOM   950  N N   . THR A 1 180 ? 155.923 173.944 208.913 1.00 55.42  ? 180 THR A N   1 
ATOM   951  C CA  . THR A 1 180 ? 157.051 173.325 208.229 1.00 55.42  ? 180 THR A CA  1 
ATOM   952  C C   . THR A 1 180 ? 157.928 174.368 207.548 1.00 55.42  ? 180 THR A C   1 
ATOM   953  O O   . THR A 1 180 ? 159.163 174.283 207.598 1.00 55.42  ? 180 THR A O   1 
ATOM   954  C CB  . THR A 1 180 ? 156.531 172.312 207.212 1.00 55.42  ? 180 THR A CB  1 
ATOM   955  O OG1 . THR A 1 180 ? 155.884 171.231 207.894 1.00 55.42  ? 180 THR A OG1 1 
ATOM   956  C CG2 . THR A 1 180 ? 157.653 171.778 206.376 1.00 55.42  ? 180 THR A CG2 1 
ATOM   957  N N   . ALA A 1 181 ? 157.308 175.357 206.900 1.00 54.67  ? 181 ALA A N   1 
ATOM   958  C CA  . ALA A 1 181 ? 158.087 176.410 206.258 1.00 54.67  ? 181 ALA A CA  1 
ATOM   959  C C   . ALA A 1 181 ? 158.924 177.176 207.275 1.00 54.67  ? 181 ALA A C   1 
ATOM   960  O O   . ALA A 1 181 ? 160.107 177.449 207.038 1.00 54.67  ? 181 ALA A O   1 
ATOM   961  C CB  . ALA A 1 181 ? 157.162 177.358 205.498 1.00 54.67  ? 181 ALA A CB  1 
ATOM   962  N N   . VAL A 1 182 ? 158.332 177.524 208.420 1.00 54.31  ? 182 VAL A N   1 
ATOM   963  C CA  . VAL A 1 182 ? 159.081 178.243 209.450 1.00 54.31  ? 182 VAL A CA  1 
ATOM   964  C C   . VAL A 1 182 ? 160.206 177.373 210.006 1.00 54.31  ? 182 VAL A C   1 
ATOM   965  O O   . VAL A 1 182 ? 161.326 177.851 210.243 1.00 54.31  ? 182 VAL A O   1 
ATOM   966  C CB  . VAL A 1 182 ? 158.131 178.719 210.563 1.00 54.31  ? 182 VAL A CB  1 
ATOM   967  C CG1 . VAL A 1 182 ? 158.918 179.343 211.701 1.00 54.31  ? 182 VAL A CG1 1 
ATOM   968  C CG2 . VAL A 1 182 ? 157.117 179.698 210.008 1.00 54.31  ? 182 VAL A CG2 1 
ATOM   969  N N   . PHE A 1 183 ? 159.922 176.086 210.223 1.00 55.03  ? 183 PHE A N   1 
ATOM   970  C CA  . PHE A 1 183 ? 160.921 175.161 210.745 1.00 55.03  ? 183 PHE A CA  1 
ATOM   971  C C   . PHE A 1 183 ? 162.118 175.059 209.811 1.00 55.03  ? 183 PHE A C   1 
ATOM   972  O O   . PHE A 1 183 ? 163.268 175.022 210.263 1.00 55.03  ? 183 PHE A O   1 
ATOM   973  C CB  . PHE A 1 183 ? 160.275 173.789 210.950 1.00 55.03  ? 183 PHE A CB  1 
ATOM   974  C CG  . PHE A 1 183 ? 161.126 172.808 211.700 1.00 55.03  ? 183 PHE A CG  1 
ATOM   975  C CD1 . PHE A 1 183 ? 161.091 172.757 213.080 1.00 55.03  ? 183 PHE A CD1 1 
ATOM   976  C CD2 . PHE A 1 183 ? 161.940 171.918 211.024 1.00 55.03  ? 183 PHE A CD2 1 
ATOM   977  C CE1 . PHE A 1 183 ? 161.864 171.850 213.771 1.00 55.03  ? 183 PHE A CE1 1 
ATOM   978  C CE2 . PHE A 1 183 ? 162.715 171.008 211.712 1.00 55.03  ? 183 PHE A CE2 1 
ATOM   979  C CZ  . PHE A 1 183 ? 162.676 170.975 213.086 1.00 55.03  ? 183 PHE A CZ  1 
ATOM   980  N N   . ALA A 1 184 ? 161.868 175.013 208.502 1.00 56.66  ? 184 ALA A N   1 
ATOM   981  C CA  . ALA A 1 184 ? 162.965 174.941 207.542 1.00 56.66  ? 184 ALA A CA  1 
ATOM   982  C C   . ALA A 1 184 ? 163.686 176.274 207.384 1.00 56.66  ? 184 ALA A C   1 
ATOM   983  O O   . ALA A 1 184 ? 164.886 176.288 207.097 1.00 56.66  ? 184 ALA A O   1 
ATOM   984  C CB  . ALA A 1 184 ? 162.448 174.463 206.187 1.00 56.66  ? 184 ALA A CB  1 
ATOM   985  N N   . ALA A 1 185 ? 162.982 177.396 207.553 1.00 57.35  ? 185 ALA A N   1 
ATOM   986  C CA  . ALA A 1 185 ? 163.621 178.699 207.391 1.00 57.35  ? 185 ALA A CA  1 
ATOM   987  C C   . ALA A 1 185 ? 164.557 179.013 208.550 1.00 57.35  ? 185 ALA A C   1 
ATOM   988  O O   . ALA A 1 185 ? 165.622 179.618 208.352 1.00 57.35  ? 185 ALA A O   1 
ATOM   989  C CB  . ALA A 1 185 ? 162.563 179.791 207.260 1.00 57.35  ? 185 ALA A CB  1 
ATOM   990  N N   . MET A 1 186 ? 164.171 178.624 209.768 1.00 60.47  ? 186 MET A N   1 
ATOM   991  C CA  . MET A 1 186 ? 164.953 179.016 210.934 1.00 60.47  ? 186 MET A CA  1 
ATOM   992  C C   . MET A 1 186 ? 166.334 178.369 210.942 1.00 60.47  ? 186 MET A C   1 
ATOM   993  O O   . MET A 1 186 ? 167.274 178.945 211.496 1.00 60.47  ? 186 MET A O   1 
ATOM   994  C CB  . MET A 1 186 ? 164.186 178.688 212.211 1.00 60.47  ? 186 MET A CB  1 
ATOM   995  C CG  . MET A 1 186 ? 163.350 179.860 212.700 1.00 60.47  ? 186 MET A CG  1 
ATOM   996  S SD  . MET A 1 186 ? 162.318 179.500 214.125 1.00 60.47  ? 186 MET A SD  1 
ATOM   997  C CE  . MET A 1 186 ? 163.329 180.165 215.438 1.00 60.47  ? 186 MET A CE  1 
ATOM   998  N N   . THR A 1 187 ? 166.491 177.208 210.304 1.00 58.70  ? 187 THR A N   1 
ATOM   999  C CA  . THR A 1 187 ? 167.809 176.584 210.211 1.00 58.70  ? 187 THR A CA  1 
ATOM   1000 C C   . THR A 1 187 ? 168.786 177.467 209.441 1.00 58.70  ? 187 THR A C   1 
ATOM   1001 O O   . THR A 1 187 ? 169.886 177.773 209.923 1.00 58.70  ? 187 THR A O   1 
ATOM   1002 C CB  . THR A 1 187 ? 167.691 175.213 209.544 1.00 58.70  ? 187 THR A CB  1 
ATOM   1003 O OG1 . THR A 1 187 ? 166.698 174.434 210.220 1.00 58.70  ? 187 THR A OG1 1 
ATOM   1004 C CG2 . THR A 1 187 ? 169.016 174.481 209.592 1.00 58.70  ? 187 THR A CG2 1 
ATOM   1005 N N   . ALA A 1 188 ? 168.396 177.892 208.236 1.00 58.62  ? 188 ALA A N   1 
ATOM   1006 C CA  . ALA A 1 188 ? 169.260 178.754 207.436 1.00 58.62  ? 188 ALA A CA  1 
ATOM   1007 C C   . ALA A 1 188 ? 169.468 180.103 208.108 1.00 58.62  ? 188 ALA A C   1 
ATOM   1008 O O   . ALA A 1 188 ? 170.572 180.665 208.065 1.00 58.62  ? 188 ALA A O   1 
ATOM   1009 C CB  . ALA A 1 188 ? 168.670 178.935 206.039 1.00 58.62  ? 188 ALA A CB  1 
ATOM   1010 N N   . ILE A 1 189 ? 168.414 180.645 208.727 1.00 58.50  ? 189 ILE A N   1 
ATOM   1011 C CA  . ILE A 1 189 ? 168.546 181.924 209.420 1.00 58.50  ? 189 ILE A CA  1 
ATOM   1012 C C   . ILE A 1 189 ? 169.594 181.819 210.521 1.00 58.50  ? 189 ILE A C   1 
ATOM   1013 O O   . ILE A 1 189 ? 170.474 182.680 210.654 1.00 58.50  ? 189 ILE A O   1 
ATOM   1014 C CB  . ILE A 1 189 ? 167.182 182.374 209.974 1.00 58.50  ? 189 ILE A CB  1 
ATOM   1015 C CG1 . ILE A 1 189 ? 166.266 182.824 208.840 1.00 58.50  ? 189 ILE A CG1 1 
ATOM   1016 C CG2 . ILE A 1 189 ? 167.350 183.512 210.946 1.00 58.50  ? 189 ILE A CG2 1 
ATOM   1017 C CD1 . ILE A 1 189 ? 164.861 183.139 209.293 1.00 58.50  ? 189 ILE A CD1 1 
ATOM   1018 N N   . GLY A 1 190 ? 169.525 180.746 211.313 1.00 60.21  ? 190 GLY A N   1 
ATOM   1019 C CA  . GLY A 1 190 ? 170.498 180.550 212.371 1.00 60.21  ? 190 GLY A CA  1 
ATOM   1020 C C   . GLY A 1 190 ? 171.907 180.366 211.849 1.00 60.21  ? 190 GLY A C   1 
ATOM   1021 O O   . GLY A 1 190 ? 172.857 180.905 212.412 1.00 60.21  ? 190 GLY A O   1 
ATOM   1022 N N   . SER A 1 191 ? 172.062 179.605 210.763 1.00 60.92  ? 191 SER A N   1 
ATOM   1023 C CA  . SER A 1 191 ? 173.392 179.407 210.188 1.00 60.92  ? 191 SER A CA  1 
ATOM   1024 C C   . SER A 1 191 ? 174.014 180.731 209.762 1.00 60.92  ? 191 SER A C   1 
ATOM   1025 O O   . SER A 1 191 ? 175.164 181.038 210.108 1.00 60.92  ? 191 SER A O   1 
ATOM   1026 C CB  . SER A 1 191 ? 173.314 178.455 208.997 1.00 60.92  ? 191 SER A CB  1 
ATOM   1027 O OG  . SER A 1 191 ? 174.586 178.295 208.399 1.00 60.92  ? 191 SER A OG  1 
ATOM   1028 N N   . VAL A 1 192 ? 173.262 181.534 209.007 1.00 61.46  ? 192 VAL A N   1 
ATOM   1029 C CA  . VAL A 1 192 ? 173.817 182.783 208.496 1.00 61.46  ? 192 VAL A CA  1 
ATOM   1030 C C   . VAL A 1 192 ? 174.100 183.757 209.635 1.00 61.46  ? 192 VAL A C   1 
ATOM   1031 O O   . VAL A 1 192 ? 175.147 184.420 209.651 1.00 61.46  ? 192 VAL A O   1 
ATOM   1032 C CB  . VAL A 1 192 ? 172.884 183.388 207.434 1.00 61.46  ? 192 VAL A CB  1 
ATOM   1033 C CG1 . VAL A 1 192 ? 173.262 184.829 207.154 1.00 61.46  ? 192 VAL A CG1 1 
ATOM   1034 C CG2 . VAL A 1 192 ? 172.961 182.569 206.161 1.00 61.46  ? 192 VAL A CG2 1 
ATOM   1035 N N   . MET A 1 193 ? 173.192 183.860 210.613 1.00 65.03  ? 193 MET A N   1 
ATOM   1036 C CA  . MET A 1 193 ? 173.461 184.790 211.704 1.00 65.03  ? 193 MET A CA  1 
ATOM   1037 C C   . MET A 1 193 ? 174.609 184.309 212.580 1.00 65.03  ? 193 MET A C   1 
ATOM   1038 O O   . MET A 1 193 ? 175.334 185.131 213.144 1.00 65.03  ? 193 MET A O   1 
ATOM   1039 C CB  . MET A 1 193 ? 172.211 185.041 212.552 1.00 65.03  ? 193 MET A CB  1 
ATOM   1040 C CG  . MET A 1 193 ? 172.043 184.116 213.742 1.00 65.03  ? 193 MET A CG  1 
ATOM   1041 S SD  . MET A 1 193 ? 170.671 184.599 214.805 1.00 65.03  ? 193 MET A SD  1 
ATOM   1042 C CE  . MET A 1 193 ? 169.329 184.654 213.630 1.00 65.03  ? 193 MET A CE  1 
ATOM   1043 N N   . GLY A 1 194 ? 174.809 182.995 212.697 1.00 63.22  ? 194 GLY A N   1 
ATOM   1044 C CA  . GLY A 1 194 ? 175.966 182.504 213.421 1.00 63.22  ? 194 GLY A CA  1 
ATOM   1045 C C   . GLY A 1 194 ? 177.261 182.843 212.716 1.00 63.22  ? 194 GLY A C   1 
ATOM   1046 O O   . GLY A 1 194 ? 178.245 183.220 213.355 1.00 63.22  ? 194 GLY A O   1 
ATOM   1047 N N   . LEU A 1 195 ? 177.272 182.729 211.388 1.00 65.35  ? 195 LEU A N   1 
ATOM   1048 C CA  . LEU A 1 195 ? 178.446 183.150 210.630 1.00 65.35  ? 195 LEU A CA  1 
ATOM   1049 C C   . LEU A 1 195 ? 178.721 184.638 210.825 1.00 65.35  ? 195 LEU A C   1 
ATOM   1050 O O   . LEU A 1 195 ? 179.867 185.042 211.058 1.00 65.35  ? 195 LEU A O   1 
ATOM   1051 C CB  . LEU A 1 195 ? 178.253 182.819 209.151 1.00 65.35  ? 195 LEU A CB  1 
ATOM   1052 C CG  . LEU A 1 195 ? 179.408 183.098 208.196 1.00 65.35  ? 195 LEU A CG  1 
ATOM   1053 C CD1 . LEU A 1 195 ? 180.662 182.378 208.651 1.00 65.35  ? 195 LEU A CD1 1 
ATOM   1054 C CD2 . LEU A 1 195 ? 179.022 182.662 206.800 1.00 65.35  ? 195 LEU A CD2 1 
ATOM   1055 N N   . VAL A 1 196 ? 177.672 185.465 210.768 1.00 66.97  ? 196 VAL A N   1 
ATOM   1056 C CA  . VAL A 1 196 ? 177.841 186.910 210.935 1.00 66.97  ? 196 VAL A CA  1 
ATOM   1057 C C   . VAL A 1 196 ? 178.373 187.235 212.327 1.00 66.97  ? 196 VAL A C   1 
ATOM   1058 O O   . VAL A 1 196 ? 179.301 188.038 212.486 1.00 66.97  ? 196 VAL A O   1 
ATOM   1059 C CB  . VAL A 1 196 ? 176.514 187.641 210.663 1.00 66.97  ? 196 VAL A CB  1 
ATOM   1060 C CG1 . VAL A 1 196 ? 176.616 189.098 211.069 1.00 66.97  ? 196 VAL A CG1 1 
ATOM   1061 C CG2 . VAL A 1 196 ? 176.131 187.527 209.206 1.00 66.97  ? 196 VAL A CG2 1 
ATOM   1062 N N   . VAL A 1 197 ? 177.782 186.625 213.357 1.00 69.63  ? 197 VAL A N   1 
ATOM   1063 C CA  . VAL A 1 197 ? 178.175 186.906 214.734 1.00 69.63  ? 197 VAL A CA  1 
ATOM   1064 C C   . VAL A 1 197 ? 179.603 186.445 214.995 1.00 69.63  ? 197 VAL A C   1 
ATOM   1065 O O   . VAL A 1 197 ? 180.395 187.161 215.618 1.00 69.63  ? 197 VAL A O   1 
ATOM   1066 C CB  . VAL A 1 197 ? 177.180 186.255 215.711 1.00 69.63  ? 197 VAL A CB  1 
ATOM   1067 C CG1 . VAL A 1 197 ? 177.813 186.070 217.077 1.00 69.63  ? 197 VAL A CG1 1 
ATOM   1068 C CG2 . VAL A 1 197 ? 175.917 187.094 215.813 1.00 69.63  ? 197 VAL A CG2 1 
ATOM   1069 N N   . GLY A 1 198 ? 179.959 185.246 214.529 1.00 72.42  ? 198 GLY A N   1 
ATOM   1070 C CA  . GLY A 1 198 ? 181.325 184.784 214.690 1.00 72.42  ? 198 GLY A CA  1 
ATOM   1071 C C   . GLY A 1 198 ? 182.325 185.668 213.974 1.00 72.42  ? 198 GLY A C   1 
ATOM   1072 O O   . GLY A 1 198 ? 183.421 185.917 214.480 1.00 72.42  ? 198 GLY A O   1 
ATOM   1073 N N   . GLY A 1 199 ? 181.965 186.155 212.785 1.00 74.05  ? 199 GLY A N   1 
ATOM   1074 C CA  . GLY A 1 199 ? 182.861 187.046 212.070 1.00 74.05  ? 199 GLY A CA  1 
ATOM   1075 C C   . GLY A 1 199 ? 183.050 188.381 212.764 1.00 74.05  ? 199 GLY A C   1 
ATOM   1076 O O   . GLY A 1 199 ? 184.169 188.891 212.852 1.00 74.05  ? 199 GLY A O   1 
ATOM   1077 N N   . ALA A 1 200 ? 181.964 188.964 213.266 1.00 74.68  ? 200 ALA A N   1 
ATOM   1078 C CA  . ALA A 1 200 ? 182.017 190.304 213.834 1.00 74.68  ? 200 ALA A CA  1 
ATOM   1079 C C   . ALA A 1 200 ? 182.335 190.326 215.321 1.00 74.68  ? 200 ALA A C   1 
ATOM   1080 O O   . ALA A 1 200 ? 182.467 191.415 215.888 1.00 74.68  ? 200 ALA A O   1 
ATOM   1081 C CB  . ALA A 1 200 ? 180.690 191.028 213.598 1.00 74.68  ? 200 ALA A CB  1 
ATOM   1082 N N   . LEU A 1 201 ? 182.457 189.169 215.968 1.00 82.32  ? 201 LEU A N   1 
ATOM   1083 C CA  . LEU A 1 201 ? 182.666 189.119 217.409 1.00 82.32  ? 201 LEU A CA  1 
ATOM   1084 C C   . LEU A 1 201 ? 183.987 188.492 217.822 1.00 82.32  ? 201 LEU A C   1 
ATOM   1085 O O   . LEU A 1 201 ? 184.481 188.791 218.910 1.00 82.32  ? 201 LEU A O   1 
ATOM   1086 C CB  . LEU A 1 201 ? 181.520 188.350 218.079 1.00 82.32  ? 201 LEU A CB  1 
ATOM   1087 C CG  . LEU A 1 201 ? 181.500 188.313 219.605 1.00 82.32  ? 201 LEU A CG  1 
ATOM   1088 C CD1 . LEU A 1 201 ? 181.580 189.722 220.163 1.00 82.32  ? 201 LEU A CD1 1 
ATOM   1089 C CD2 . LEU A 1 201 ? 180.252 187.610 220.101 1.00 82.32  ? 201 LEU A CD2 1 
ATOM   1090 N N   . THR A 1 202 ? 184.584 187.650 216.983 1.00 88.59  ? 202 THR A N   1 
ATOM   1091 C CA  . THR A 1 202 ? 185.799 186.937 217.351 1.00 88.59  ? 202 THR A CA  1 
ATOM   1092 C C   . THR A 1 202 ? 187.056 187.774 217.173 1.00 88.59  ? 202 THR A C   1 
ATOM   1093 O O   . THR A 1 202 ? 188.149 187.211 217.067 1.00 88.59  ? 202 THR A O   1 
ATOM   1094 C CB  . THR A 1 202 ? 185.922 185.640 216.548 1.00 88.59  ? 202 THR A CB  1 
ATOM   1095 O OG1 . THR A 1 202 ? 185.675 185.906 215.162 1.00 88.59  ? 202 THR A OG1 1 
ATOM   1096 C CG2 . THR A 1 202 ? 184.926 184.608 217.050 1.00 88.59  ? 202 THR A CG2 1 
ATOM   1097 N N   . GLU A 1 203 ? 186.936 189.096 217.120 1.00 93.21  ? 203 GLU A N   1 
ATOM   1098 C CA  . GLU A 1 203 ? 188.098 189.969 217.065 1.00 93.21  ? 203 GLU A CA  1 
ATOM   1099 C C   . GLU A 1 203 ? 188.449 190.553 218.427 1.00 93.21  ? 203 GLU A C   1 
ATOM   1100 O O   . GLU A 1 203 ? 189.360 191.381 218.520 1.00 93.21  ? 203 GLU A O   1 
ATOM   1101 C CB  . GLU A 1 203 ? 187.868 191.087 216.048 1.00 93.21  ? 203 GLU A CB  1 
ATOM   1102 C CG  . GLU A 1 203 ? 187.571 190.568 214.650 1.00 93.21  ? 203 GLU A CG  1 
ATOM   1103 C CD  . GLU A 1 203 ? 188.630 189.602 214.150 1.00 93.21  ? 203 GLU A CD  1 
ATOM   1104 O OE1 . GLU A 1 203 ? 189.831 189.862 214.372 1.00 93.21  ? 203 GLU A OE1 1 
ATOM   1105 O OE2 . GLU A 1 203 ? 188.258 188.576 213.543 1.00 93.21  ? 203 GLU A OE2 1 
ATOM   1106 N N   . VAL A 1 204 ? 187.748 190.140 219.484 1.00 91.61  ? 204 VAL A N   1 
ATOM   1107 C CA  . VAL A 1 204 ? 188.036 190.565 220.848 1.00 91.61  ? 204 VAL A CA  1 
ATOM   1108 C C   . VAL A 1 204 ? 188.305 189.372 221.761 1.00 91.61  ? 204 VAL A C   1 
ATOM   1109 O O   . VAL A 1 204 ? 189.304 189.344 222.485 1.00 91.61  ? 204 VAL A O   1 
ATOM   1110 C CB  . VAL A 1 204 ? 186.902 191.448 221.417 1.00 91.61  ? 204 VAL A CB  1 
ATOM   1111 C CG1 . VAL A 1 204 ? 186.960 192.833 220.799 1.00 91.61  ? 204 VAL A CG1 1 
ATOM   1112 C CG2 . VAL A 1 204 ? 185.545 190.820 221.163 1.00 91.61  ? 204 VAL A CG2 1 
ATOM   1113 N N   . SER A 1 205 ? 187.429 188.370 221.729 1.00 87.67  ? 205 SER A N   1 
ATOM   1114 C CA  . SER A 1 205 ? 187.562 187.195 222.577 1.00 87.67  ? 205 SER A CA  1 
ATOM   1115 C C   . SER A 1 205 ? 186.623 186.113 222.069 1.00 87.67  ? 205 SER A C   1 
ATOM   1116 O O   . SER A 1 205 ? 185.509 186.410 221.634 1.00 87.67  ? 205 SER A O   1 
ATOM   1117 C CB  . SER A 1 205 ? 187.243 187.523 224.042 1.00 87.67  ? 205 SER A CB  1 
ATOM   1118 O OG  . SER A 1 205 ? 187.448 186.394 224.872 1.00 87.67  ? 205 SER A OG  1 
ATOM   1119 N N   . TRP A 1 206 ? 187.078 184.862 222.132 1.00 82.57  ? 206 TRP A N   1 
ATOM   1120 C CA  . TRP A 1 206 ? 186.244 183.741 221.724 1.00 82.57  ? 206 TRP A CA  1 
ATOM   1121 C C   . TRP A 1 206 ? 185.229 183.343 222.784 1.00 82.57  ? 206 TRP A C   1 
ATOM   1122 O O   . TRP A 1 206 ? 184.304 182.585 222.476 1.00 82.57  ? 206 TRP A O   1 
ATOM   1123 C CB  . TRP A 1 206 ? 187.116 182.534 221.371 1.00 82.57  ? 206 TRP A CB  1 
ATOM   1124 C CG  . TRP A 1 206 ? 187.876 181.977 222.532 1.00 82.57  ? 206 TRP A CG  1 
ATOM   1125 C CD1 . TRP A 1 206 ? 189.125 182.337 222.938 1.00 82.57  ? 206 TRP A CD1 1 
ATOM   1126 C CD2 . TRP A 1 206 ? 187.440 180.953 223.434 1.00 82.57  ? 206 TRP A CD2 1 
ATOM   1127 N NE1 . TRP A 1 206 ? 189.495 181.604 224.039 1.00 82.57  ? 206 TRP A NE1 1 
ATOM   1128 C CE2 . TRP A 1 206 ? 188.477 180.747 224.363 1.00 82.57  ? 206 TRP A CE2 1 
ATOM   1129 C CE3 . TRP A 1 206 ? 186.273 180.192 223.547 1.00 82.57  ? 206 TRP A CE3 1 
ATOM   1130 C CZ2 . TRP A 1 206 ? 188.383 179.813 225.390 1.00 82.57  ? 206 TRP A CZ2 1 
ATOM   1131 C CZ3 . TRP A 1 206 ? 186.182 179.267 224.567 1.00 82.57  ? 206 TRP A CZ3 1 
ATOM   1132 C CH2 . TRP A 1 206 ? 187.230 179.085 225.475 1.00 82.57  ? 206 TRP A CH2 1 
ATOM   1133 N N   . ARG A 1 207 ? 185.375 183.829 224.018 1.00 79.96  ? 207 ARG A N   1 
ATOM   1134 C CA  . ARG A 1 207 ? 184.413 183.491 225.061 1.00 79.96  ? 207 ARG A CA  1 
ATOM   1135 C C   . ARG A 1 207 ? 183.104 184.249 224.888 1.00 79.96  ? 207 ARG A C   1 
ATOM   1136 O O   . ARG A 1 207 ? 182.046 183.749 225.281 1.00 79.96  ? 207 ARG A O   1 
ATOM   1137 C CB  . ARG A 1 207 ? 185.012 183.770 226.437 1.00 79.96  ? 207 ARG A CB  1 
ATOM   1138 C CG  . ARG A 1 207 ? 186.456 183.327 226.575 1.00 79.96  ? 207 ARG A CG  1 
ATOM   1139 C CD  . ARG A 1 207 ? 186.849 183.171 228.029 1.00 79.96  ? 207 ARG A CD  1 
ATOM   1140 N NE  . ARG A 1 207 ? 188.177 182.588 228.169 1.00 79.96  ? 207 ARG A NE  1 
ATOM   1141 C CZ  . ARG A 1 207 ? 188.432 181.450 228.799 1.00 79.96  ? 207 ARG A CZ  1 
ATOM   1142 N NH1 . ARG A 1 207 ? 187.469 180.742 229.363 1.00 79.96  ? 207 ARG A NH1 1 
ATOM   1143 N NH2 . ARG A 1 207 ? 189.685 181.012 228.863 1.00 79.96  ? 207 ARG A NH2 1 
ATOM   1144 N N   . TRP A 1 208 ? 183.153 185.452 224.312 1.00 81.02  ? 208 TRP A N   1 
ATOM   1145 C CA  . TRP A 1 208 ? 181.930 186.205 224.067 1.00 81.02  ? 208 TRP A CA  1 
ATOM   1146 C C   . TRP A 1 208 ? 181.084 185.582 222.967 1.00 81.02  ? 208 TRP A C   1 
ATOM   1147 O O   . TRP A 1 208 ? 179.881 185.855 222.897 1.00 81.02  ? 208 TRP A O   1 
ATOM   1148 C CB  . TRP A 1 208 ? 182.260 187.653 223.704 1.00 81.02  ? 208 TRP A CB  1 
ATOM   1149 C CG  . TRP A 1 208 ? 182.780 188.463 224.849 1.00 81.02  ? 208 TRP A CG  1 
ATOM   1150 C CD1 . TRP A 1 208 ? 184.042 188.956 224.996 1.00 81.02  ? 208 TRP A CD1 1 
ATOM   1151 C CD2 . TRP A 1 208 ? 182.051 188.875 226.010 1.00 81.02  ? 208 TRP A CD2 1 
ATOM   1152 N NE1 . TRP A 1 208 ? 184.145 189.650 226.176 1.00 81.02  ? 208 TRP A NE1 1 
ATOM   1153 C CE2 . TRP A 1 208 ? 182.936 189.614 226.818 1.00 81.02  ? 208 TRP A CE2 1 
ATOM   1154 C CE3 . TRP A 1 208 ? 180.736 188.690 226.446 1.00 81.02  ? 208 TRP A CE3 1 
ATOM   1155 C CZ2 . TRP A 1 208 ? 182.550 190.168 228.035 1.00 81.02  ? 208 TRP A CZ2 1 
ATOM   1156 C CZ3 . TRP A 1 208 ? 180.355 189.240 227.654 1.00 81.02  ? 208 TRP A CZ3 1 
ATOM   1157 C CH2 . TRP A 1 208 ? 181.258 189.971 228.434 1.00 81.02  ? 208 TRP A CH2 1 
ATOM   1158 N N   . ALA A 1 209 ? 181.686 184.760 222.104 1.00 78.70  ? 209 ALA A N   1 
ATOM   1159 C CA  . ALA A 1 209 ? 180.927 184.113 221.040 1.00 78.70  ? 209 ALA A CA  1 
ATOM   1160 C C   . ALA A 1 209 ? 179.995 183.039 221.585 1.00 78.70  ? 209 ALA A C   1 
ATOM   1161 O O   . ALA A 1 209 ? 178.910 182.826 221.035 1.00 78.70  ? 209 ALA A O   1 
ATOM   1162 C CB  . ALA A 1 209 ? 181.881 183.520 220.005 1.00 78.70  ? 209 ALA A CB  1 
ATOM   1163 N N   . PHE A 1 210 ? 180.396 182.356 222.654 1.00 75.29  ? 210 PHE A N   1 
ATOM   1164 C CA  . PHE A 1 210 ? 179.578 181.313 223.255 1.00 75.29  ? 210 PHE A CA  1 
ATOM   1165 C C   . PHE A 1 210 ? 178.492 181.855 224.172 1.00 75.29  ? 210 PHE A C   1 
ATOM   1166 O O   . PHE A 1 210 ? 177.614 181.090 224.581 1.00 75.29  ? 210 PHE A O   1 
ATOM   1167 C CB  . PHE A 1 210 ? 180.459 180.342 224.046 1.00 75.29  ? 210 PHE A CB  1 
ATOM   1168 C CG  . PHE A 1 210 ? 181.197 179.357 223.190 1.00 75.29  ? 210 PHE A CG  1 
ATOM   1169 C CD1 . PHE A 1 210 ? 180.510 178.414 222.446 1.00 75.29  ? 210 PHE A CD1 1 
ATOM   1170 C CD2 . PHE A 1 210 ? 182.578 179.373 223.130 1.00 75.29  ? 210 PHE A CD2 1 
ATOM   1171 C CE1 . PHE A 1 210 ? 181.188 177.507 221.658 1.00 75.29  ? 210 PHE A CE1 1 
ATOM   1172 C CE2 . PHE A 1 210 ? 183.260 178.468 222.344 1.00 75.29  ? 210 PHE A CE2 1 
ATOM   1173 C CZ  . PHE A 1 210 ? 182.564 177.534 221.607 1.00 75.29  ? 210 PHE A CZ  1 
ATOM   1174 N N   . LEU A 1 211 ? 178.528 183.142 224.511 1.00 74.61  ? 211 LEU A N   1 
ATOM   1175 C CA  . LEU A 1 211 ? 177.555 183.716 225.429 1.00 74.61  ? 211 LEU A CA  1 
ATOM   1176 C C   . LEU A 1 211 ? 176.340 184.308 224.730 1.00 74.61  ? 211 LEU A C   1 
ATOM   1177 O O   . LEU A 1 211 ? 175.375 184.672 225.408 1.00 74.61  ? 211 LEU A O   1 
ATOM   1178 C CB  . LEU A 1 211 ? 178.215 184.795 226.292 1.00 74.61  ? 211 LEU A CB  1 
ATOM   1179 C CG  . LEU A 1 211 ? 179.056 184.311 227.473 1.00 74.61  ? 211 LEU A CG  1 
ATOM   1180 C CD1 . LEU A 1 211 ? 179.428 185.481 228.364 1.00 74.61  ? 211 LEU A CD1 1 
ATOM   1181 C CD2 . LEU A 1 211 ? 178.323 183.246 228.264 1.00 74.61  ? 211 LEU A CD2 1 
ATOM   1182 N N   . VAL A 1 212 ? 176.359 184.415 223.399 1.00 74.64  ? 212 VAL A N   1 
ATOM   1183 C CA  . VAL A 1 212 ? 175.196 184.928 222.687 1.00 74.64  ? 212 VAL A CA  1 
ATOM   1184 C C   . VAL A 1 212 ? 174.084 183.889 222.639 1.00 74.64  ? 212 VAL A C   1 
ATOM   1185 O O   . VAL A 1 212 ? 172.925 184.230 222.381 1.00 74.64  ? 212 VAL A O   1 
ATOM   1186 C CB  . VAL A 1 212 ? 175.599 185.389 221.272 1.00 74.64  ? 212 VAL A CB  1 
ATOM   1187 C CG1 . VAL A 1 212 ? 176.062 184.210 220.436 1.00 74.64  ? 212 VAL A CG1 1 
ATOM   1188 C CG2 . VAL A 1 212 ? 174.465 186.144 220.590 1.00 74.64  ? 212 VAL A CG2 1 
ATOM   1189 N N   . ASN A 1 213 ? 174.405 182.621 222.900 1.00 73.69  ? 213 ASN A N   1 
ATOM   1190 C CA  . ASN A 1 213 ? 173.387 181.579 222.916 1.00 73.69  ? 213 ASN A CA  1 
ATOM   1191 C C   . ASN A 1 213 ? 172.404 181.746 224.065 1.00 73.69  ? 213 ASN A C   1 
ATOM   1192 O O   . ASN A 1 213 ? 171.255 181.310 223.947 1.00 73.69  ? 213 ASN A O   1 
ATOM   1193 C CB  . ASN A 1 213 ? 174.042 180.201 223.025 1.00 73.69  ? 213 ASN A CB  1 
ATOM   1194 C CG  . ASN A 1 213 ? 174.770 179.795 221.763 1.00 73.69  ? 213 ASN A CG  1 
ATOM   1195 O OD1 . ASN A 1 213 ? 174.212 179.851 220.667 1.00 73.69  ? 213 ASN A OD1 1 
ATOM   1196 N ND2 . ASN A 1 213 ? 176.023 179.390 221.907 1.00 73.69  ? 213 ASN A ND2 1 
ATOM   1197 N N   . VAL A 1 214 ? 172.836 182.351 225.168 1.00 71.05  ? 214 VAL A N   1 
ATOM   1198 C CA  . VAL A 1 214 ? 172.070 182.394 226.412 1.00 71.05  ? 214 VAL A CA  1 
ATOM   1199 C C   . VAL A 1 214 ? 170.783 183.205 226.271 1.00 71.05  ? 214 VAL A C   1 
ATOM   1200 O O   . VAL A 1 214 ? 169.715 182.702 226.651 1.00 71.05  ? 214 VAL A O   1 
ATOM   1201 C CB  . VAL A 1 214 ? 172.937 182.936 227.559 1.00 71.05  ? 214 VAL A CB  1 
ATOM   1202 C CG1 . VAL A 1 214 ? 172.161 182.931 228.866 1.00 71.05  ? 214 VAL A CG1 1 
ATOM   1203 C CG2 . VAL A 1 214 ? 174.223 182.144 227.665 1.00 71.05  ? 214 VAL A CG2 1 
ATOM   1204 N N   . PRO A 1 215 ? 170.814 184.455 225.778 1.00 71.12  ? 215 PRO A N   1 
ATOM   1205 C CA  . PRO A 1 215 ? 169.547 185.197 225.659 1.00 71.12  ? 215 PRO A CA  1 
ATOM   1206 C C   . PRO A 1 215 ? 168.554 184.536 224.724 1.00 71.12  ? 215 PRO A C   1 
ATOM   1207 O O   . PRO A 1 215 ? 167.346 184.527 225.002 1.00 71.12  ? 215 PRO A O   1 
ATOM   1208 C CB  . PRO A 1 215 ? 169.994 186.569 225.135 1.00 71.12  ? 215 PRO A CB  1 
ATOM   1209 C CG  . PRO A 1 215 ? 171.422 186.670 225.509 1.00 71.12  ? 215 PRO A CG  1 
ATOM   1210 C CD  . PRO A 1 215 ? 171.952 185.291 225.356 1.00 71.12  ? 215 PRO A CD  1 
ATOM   1211 N N   . ILE A 1 216 ? 169.037 183.962 223.621 1.00 69.54  ? 216 ILE A N   1 
ATOM   1212 C CA  . ILE A 1 216 ? 168.135 183.323 222.672 1.00 69.54  ? 216 ILE A CA  1 
ATOM   1213 C C   . ILE A 1 216 ? 167.541 182.058 223.277 1.00 69.54  ? 216 ILE A C   1 
ATOM   1214 O O   . ILE A 1 216 ? 166.345 181.784 223.127 1.00 69.54  ? 216 ILE A O   1 
ATOM   1215 C CB  . ILE A 1 216 ? 168.868 183.041 221.350 1.00 69.54  ? 216 ILE A CB  1 
ATOM   1216 C CG1 . ILE A 1 216 ? 169.338 184.352 220.727 1.00 69.54  ? 216 ILE A CG1 1 
ATOM   1217 C CG2 . ILE A 1 216 ? 167.936 182.369 220.374 1.00 69.54  ? 216 ILE A CG2 1 
ATOM   1218 C CD1 . ILE A 1 216 ? 170.285 184.167 219.570 1.00 69.54  ? 216 ILE A CD1 1 
ATOM   1219 N N   . GLY A 1 217 ? 168.356 181.280 223.992 1.00 67.96  ? 217 GLY A N   1 
ATOM   1220 C CA  . GLY A 1 217 ? 167.823 180.119 224.681 1.00 67.96  ? 217 GLY A CA  1 
ATOM   1221 C C   . GLY A 1 217 ? 166.775 180.492 225.710 1.00 67.96  ? 217 GLY A C   1 
ATOM   1222 O O   . GLY A 1 217 ? 165.744 179.827 225.827 1.00 67.96  ? 217 GLY A O   1 
ATOM   1223 N N   . LEU A 1 218 ? 167.017 181.569 226.460 1.00 68.46  ? 218 LEU A N   1 
ATOM   1224 C CA  . LEU A 1 218 ? 166.046 181.997 227.463 1.00 68.46  ? 218 LEU A CA  1 
ATOM   1225 C C   . LEU A 1 218 ? 164.739 182.450 226.822 1.00 68.46  ? 218 LEU A C   1 
ATOM   1226 O O   . LEU A 1 218 ? 163.651 182.103 227.304 1.00 68.46  ? 218 LEU A O   1 
ATOM   1227 C CB  . LEU A 1 218 ? 166.638 183.111 228.323 1.00 68.46  ? 218 LEU A CB  1 
ATOM   1228 C CG  . LEU A 1 218 ? 167.712 182.667 229.316 1.00 68.46  ? 218 LEU A CG  1 
ATOM   1229 C CD1 . LEU A 1 218 ? 168.513 183.859 229.813 1.00 68.46  ? 218 LEU A CD1 1 
ATOM   1230 C CD2 . LEU A 1 218 ? 167.085 181.916 230.477 1.00 68.46  ? 218 LEU A CD2 1 
ATOM   1231 N N   . VAL A 1 219 ? 164.816 183.217 225.731 1.00 69.12  ? 219 VAL A N   1 
ATOM   1232 C CA  . VAL A 1 219 ? 163.588 183.696 225.104 1.00 69.12  ? 219 VAL A CA  1 
ATOM   1233 C C   . VAL A 1 219 ? 162.814 182.538 224.481 1.00 69.12  ? 219 VAL A C   1 
ATOM   1234 O O   . VAL A 1 219 ? 161.578 182.510 224.526 1.00 69.12  ? 219 VAL A O   1 
ATOM   1235 C CB  . VAL A 1 219 ? 163.887 184.815 224.085 1.00 69.12  ? 219 VAL A CB  1 
ATOM   1236 C CG1 . VAL A 1 219 ? 164.508 184.271 222.816 1.00 69.12  ? 219 VAL A CG1 1 
ATOM   1237 C CG2 . VAL A 1 219 ? 162.617 185.580 223.761 1.00 69.12  ? 219 VAL A CG2 1 
ATOM   1238 N N   . MET A 1 220 ? 163.516 181.548 223.918 1.00 68.24  ? 220 MET A N   1 
ATOM   1239 C CA  . MET A 1 220 ? 162.810 180.395 223.366 1.00 68.24  ? 220 MET A CA  1 
ATOM   1240 C C   . MET A 1 220 ? 162.211 179.529 224.465 1.00 68.24  ? 220 MET A C   1 
ATOM   1241 O O   . MET A 1 220 ? 161.134 178.955 224.282 1.00 68.24  ? 220 MET A O   1 
ATOM   1242 C CB  . MET A 1 220 ? 163.731 179.574 222.466 1.00 68.24  ? 220 MET A CB  1 
ATOM   1243 C CG  . MET A 1 220 ? 164.311 180.371 221.317 1.00 68.24  ? 220 MET A CG  1 
ATOM   1244 S SD  . MET A 1 220 ? 163.147 180.533 219.955 1.00 68.24  ? 220 MET A SD  1 
ATOM   1245 C CE  . MET A 1 220 ? 164.144 181.426 218.770 1.00 68.24  ? 220 MET A CE  1 
ATOM   1246 N N   . ILE A 1 221 ? 162.882 179.424 225.614 1.00 66.72  ? 221 ILE A N   1 
ATOM   1247 C CA  . ILE A 1 221 ? 162.292 178.707 226.742 1.00 66.72  ? 221 ILE A CA  1 
ATOM   1248 C C   . ILE A 1 221 ? 161.009 179.393 227.189 1.00 66.72  ? 221 ILE A C   1 
ATOM   1249 O O   . ILE A 1 221 ? 159.987 178.737 227.433 1.00 66.72  ? 221 ILE A O   1 
ATOM   1250 C CB  . ILE A 1 221 ? 163.302 178.595 227.899 1.00 66.72  ? 221 ILE A CB  1 
ATOM   1251 C CG1 . ILE A 1 221 ? 164.326 177.499 227.612 1.00 66.72  ? 221 ILE A CG1 1 
ATOM   1252 C CG2 . ILE A 1 221 ? 162.587 178.313 229.207 1.00 66.72  ? 221 ILE A CG2 1 
ATOM   1253 C CD1 . ILE A 1 221 ? 165.268 177.239 228.757 1.00 66.72  ? 221 ILE A CD1 1 
ATOM   1254 N N   . TYR A 1 222 ? 161.037 180.724 227.291 1.00 71.54  ? 222 TYR A N   1 
ATOM   1255 C CA  . TYR A 1 222 ? 159.835 181.456 227.680 1.00 71.54  ? 222 TYR A CA  1 
ATOM   1256 C C   . TYR A 1 222 ? 158.711 181.260 226.668 1.00 71.54  ? 222 TYR A C   1 
ATOM   1257 O O   . TYR A 1 222 ? 157.557 181.024 227.049 1.00 71.54  ? 222 TYR A O   1 
ATOM   1258 C CB  . TYR A 1 222 ? 160.152 182.941 227.842 1.00 71.54  ? 222 TYR A CB  1 
ATOM   1259 C CG  . TYR A 1 222 ? 158.921 183.809 227.951 1.00 71.54  ? 222 TYR A CG  1 
ATOM   1260 C CD1 . TYR A 1 222 ? 158.131 183.784 229.091 1.00 71.54  ? 222 TYR A CD1 1 
ATOM   1261 C CD2 . TYR A 1 222 ? 158.544 184.648 226.912 1.00 71.54  ? 222 TYR A CD2 1 
ATOM   1262 C CE1 . TYR A 1 222 ? 157.003 184.572 229.195 1.00 71.54  ? 222 TYR A CE1 1 
ATOM   1263 C CE2 . TYR A 1 222 ? 157.418 185.439 227.007 1.00 71.54  ? 222 TYR A CE2 1 
ATOM   1264 C CZ  . TYR A 1 222 ? 156.651 185.396 228.151 1.00 71.54  ? 222 TYR A CZ  1 
ATOM   1265 O OH  . TYR A 1 222 ? 155.527 186.182 228.252 1.00 71.54  ? 222 TYR A OH  1 
ATOM   1266 N N   . LEU A 1 223 ? 159.029 181.353 225.373 1.00 70.35  ? 223 LEU A N   1 
ATOM   1267 C CA  . LEU A 1 223 ? 158.005 181.189 224.345 1.00 70.35  ? 223 LEU A CA  1 
ATOM   1268 C C   . LEU A 1 223 ? 157.421 179.783 224.361 1.00 70.35  ? 223 LEU A C   1 
ATOM   1269 O O   . LEU A 1 223 ? 156.208 179.607 224.205 1.00 70.35  ? 223 LEU A O   1 
ATOM   1270 C CB  . LEU A 1 223 ? 158.584 181.507 222.967 1.00 70.35  ? 223 LEU A CB  1 
ATOM   1271 C CG  . LEU A 1 223 ? 158.838 182.976 222.638 1.00 70.35  ? 223 LEU A CG  1 
ATOM   1272 C CD1 . LEU A 1 223 ? 159.675 183.097 221.378 1.00 70.35  ? 223 LEU A CD1 1 
ATOM   1273 C CD2 . LEU A 1 223 ? 157.526 183.718 222.483 1.00 70.35  ? 223 LEU A CD2 1 
ATOM   1274 N N   . ALA A 1 224 ? 158.269 178.767 224.537 1.00 71.18  ? 224 ALA A N   1 
ATOM   1275 C CA  . ALA A 1 224 ? 157.781 177.395 224.593 1.00 71.18  ? 224 ALA A CA  1 
ATOM   1276 C C   . ALA A 1 224 ? 156.897 177.171 225.810 1.00 71.18  ? 224 ALA A C   1 
ATOM   1277 O O   . ALA A 1 224 ? 155.882 176.472 225.725 1.00 71.18  ? 224 ALA A O   1 
ATOM   1278 C CB  . ALA A 1 224 ? 158.956 176.419 224.599 1.00 71.18  ? 224 ALA A CB  1 
ATOM   1279 N N   . ARG A 1 225 ? 157.268 177.748 226.955 1.00 75.28  ? 225 ARG A N   1 
ATOM   1280 C CA  . ARG A 1 225 ? 156.447 177.586 228.149 1.00 75.28  ? 225 ARG A CA  1 
ATOM   1281 C C   . ARG A 1 225 ? 155.097 178.278 228.000 1.00 75.28  ? 225 ARG A C   1 
ATOM   1282 O O   . ARG A 1 225 ? 154.064 177.720 228.386 1.00 75.28  ? 225 ARG A O   1 
ATOM   1283 C CB  . ARG A 1 225 ? 157.185 178.113 229.378 1.00 75.28  ? 225 ARG A CB  1 
ATOM   1284 C CG  . ARG A 1 225 ? 156.423 177.894 230.671 1.00 75.28  ? 225 ARG A CG  1 
ATOM   1285 C CD  . ARG A 1 225 ? 157.216 178.339 231.885 1.00 75.28  ? 225 ARG A CD  1 
ATOM   1286 N NE  . ARG A 1 225 ? 156.437 178.199 233.110 1.00 75.28  ? 225 ARG A NE  1 
ATOM   1287 C CZ  . ARG A 1 225 ? 156.365 177.089 233.831 1.00 75.28  ? 225 ARG A CZ  1 
ATOM   1288 N NH1 . ARG A 1 225 ? 157.015 175.992 233.480 1.00 75.28  ? 225 ARG A NH1 1 
ATOM   1289 N NH2 . ARG A 1 225 ? 155.620 177.079 234.933 1.00 75.28  ? 225 ARG A NH2 1 
ATOM   1290 N N   . THR A 1 226 ? 155.078 179.489 227.442 1.00 76.27  ? 226 THR A N   1 
ATOM   1291 C CA  . THR A 1 226 ? 153.843 180.261 227.384 1.00 76.27  ? 226 THR A CA  1 
ATOM   1292 C C   . THR A 1 226 ? 152.991 179.973 226.154 1.00 76.27  ? 226 THR A C   1 
ATOM   1293 O O   . THR A 1 226 ? 151.845 180.428 226.102 1.00 76.27  ? 226 THR A O   1 
ATOM   1294 C CB  . THR A 1 226 ? 154.143 181.761 227.427 1.00 76.27  ? 226 THR A CB  1 
ATOM   1295 O OG1 . THR A 1 226 ? 152.922 182.481 227.629 1.00 76.27  ? 226 THR A OG1 1 
ATOM   1296 C CG2 . THR A 1 226 ? 154.756 182.213 226.117 1.00 76.27  ? 226 THR A CG2 1 
ATOM   1297 N N   . ALA A 1 227 ? 153.506 179.237 225.170 1.00 76.04  ? 227 ALA A N   1 
ATOM   1298 C CA  . ALA A 1 227 ? 152.783 178.999 223.927 1.00 76.04  ? 227 ALA A CA  1 
ATOM   1299 C C   . ALA A 1 227 ? 152.330 177.557 223.764 1.00 76.04  ? 227 ALA A C   1 
ATOM   1300 O O   . ALA A 1 227 ? 151.155 177.308 223.483 1.00 76.04  ? 227 ALA A O   1 
ATOM   1301 C CB  . ALA A 1 227 ? 153.651 179.409 222.730 1.00 76.04  ? 227 ALA A CB  1 
ATOM   1302 N N   . LEU A 1 228 ? 153.236 176.597 223.922 1.00 78.24  ? 228 LEU A N   1 
ATOM   1303 C CA  . LEU A 1 228 ? 152.868 175.196 223.794 1.00 78.24  ? 228 LEU A CA  1 
ATOM   1304 C C   . LEU A 1 228 ? 152.018 174.759 224.983 1.00 78.24  ? 228 LEU A C   1 
ATOM   1305 O O   . LEU A 1 228 ? 152.051 175.357 226.060 1.00 78.24  ? 228 LEU A O   1 
ATOM   1306 C CB  . LEU A 1 228 ? 154.114 174.318 223.687 1.00 78.24  ? 228 LEU A CB  1 
ATOM   1307 C CG  . LEU A 1 228 ? 155.162 174.706 222.643 1.00 78.24  ? 228 LEU A CG  1 
ATOM   1308 C CD1 . LEU A 1 228 ? 156.201 173.610 222.512 1.00 78.24  ? 228 LEU A CD1 1 
ATOM   1309 C CD2 . LEU A 1 228 ? 154.514 174.990 221.301 1.00 78.24  ? 228 LEU A CD2 1 
ATOM   1310 N N   . ARG A 1 229 ? 151.248 173.696 224.775 1.00 90.28  ? 229 ARG A N   1 
ATOM   1311 C CA  . ARG A 1 229 ? 150.334 173.194 225.786 1.00 90.28  ? 229 ARG A CA  1 
ATOM   1312 C C   . ARG A 1 229 ? 150.558 171.704 226.008 1.00 90.28  ? 229 ARG A C   1 
ATOM   1313 O O   . ARG A 1 229 ? 151.105 170.999 225.156 1.00 90.28  ? 229 ARG A O   1 
ATOM   1314 C CB  . ARG A 1 229 ? 148.878 173.459 225.390 1.00 90.28  ? 229 ARG A CB  1 
ATOM   1315 C CG  . ARG A 1 229 ? 148.522 174.933 225.394 1.00 90.28  ? 229 ARG A CG  1 
ATOM   1316 C CD  . ARG A 1 229 ? 147.081 175.169 224.996 1.00 90.28  ? 229 ARG A CD  1 
ATOM   1317 N NE  . ARG A 1 229 ? 146.750 176.588 225.029 1.00 90.28  ? 229 ARG A NE  1 
ATOM   1318 C CZ  . ARG A 1 229 ? 146.875 177.408 223.995 1.00 90.28  ? 229 ARG A CZ  1 
ATOM   1319 N NH1 . ARG A 1 229 ? 147.320 176.980 222.825 1.00 90.28  ? 229 ARG A NH1 1 
ATOM   1320 N NH2 . ARG A 1 229 ? 146.546 178.688 224.138 1.00 90.28  ? 229 ARG A NH2 1 
ATOM   1321 N N   . GLU A 1 230 ? 150.129 171.235 227.176 1.00 99.19  ? 230 GLU A N   1 
ATOM   1322 C CA  . GLU A 1 230 ? 150.300 169.839 227.541 1.00 99.19  ? 230 GLU A CA  1 
ATOM   1323 C C   . GLU A 1 230 ? 149.414 168.943 226.679 1.00 99.19  ? 230 GLU A C   1 
ATOM   1324 O O   . GLU A 1 230 ? 148.399 169.371 226.124 1.00 99.19  ? 230 GLU A O   1 
ATOM   1325 C CB  . GLU A 1 230 ? 149.972 169.628 229.019 1.00 99.19  ? 230 GLU A CB  1 
ATOM   1326 C CG  . GLU A 1 230 ? 151.104 169.986 229.968 1.00 99.19  ? 230 GLU A CG  1 
ATOM   1327 C CD  . GLU A 1 230 ? 151.171 171.473 230.262 1.00 99.19  ? 230 GLU A CD  1 
ATOM   1328 O OE1 . GLU A 1 230 ? 150.220 172.196 229.899 1.00 99.19  ? 230 GLU A OE1 1 
ATOM   1329 O OE2 . GLU A 1 230 ? 152.174 171.918 230.858 1.00 99.19  ? 230 GLU A OE2 1 
ATOM   1330 N N   . THR A 1 231 ? 149.817 167.678 226.571 1.00 105.17 ? 231 THR A N   1 
ATOM   1331 C CA  . THR A 1 231 ? 149.085 166.693 225.786 1.00 105.17 ? 231 THR A CA  1 
ATOM   1332 C C   . THR A 1 231 ? 148.138 165.845 226.621 1.00 105.17 ? 231 THR A C   1 
ATOM   1333 O O   . THR A 1 231 ? 147.083 165.441 226.119 1.00 105.17 ? 231 THR A O   1 
ATOM   1334 C CB  . THR A 1 231 ? 150.065 165.771 225.048 1.00 105.17 ? 231 THR A CB  1 
ATOM   1335 O OG1 . THR A 1 231 ? 151.074 166.559 224.405 1.00 105.17 ? 231 THR A OG1 1 
ATOM   1336 C CG2 . THR A 1 231 ? 149.341 164.941 223.998 1.00 105.17 ? 231 THR A CG2 1 
ATOM   1337 N N   . ASN A 1 232 ? 148.488 165.573 227.879 1.00 109.07 ? 232 ASN A N   1 
ATOM   1338 C CA  . ASN A 1 232 ? 147.715 164.719 228.782 1.00 109.07 ? 232 ASN A CA  1 
ATOM   1339 C C   . ASN A 1 232 ? 147.578 163.293 228.260 1.00 109.07 ? 232 ASN A C   1 
ATOM   1340 O O   . ASN A 1 232 ? 146.658 162.570 228.654 1.00 109.07 ? 232 ASN A O   1 
ATOM   1341 C CB  . ASN A 1 232 ? 146.327 165.307 229.071 1.00 109.07 ? 232 ASN A CB  1 
ATOM   1342 C CG  . ASN A 1 232 ? 146.394 166.677 229.712 1.00 109.07 ? 232 ASN A CG  1 
ATOM   1343 O OD1 . ASN A 1 232 ? 146.929 166.837 230.809 1.00 109.07 ? 232 ASN A OD1 1 
ATOM   1344 N ND2 . ASN A 1 232 ? 145.840 167.676 229.033 1.00 109.07 ? 232 ASN A ND2 1 
ATOM   1345 N N   . LYS A 1 233 ? 148.477 162.871 227.376 1.00 107.87 ? 233 LYS A N   1 
ATOM   1346 C CA  . LYS A 1 233 ? 148.438 161.510 226.863 1.00 107.87 ? 233 LYS A CA  1 
ATOM   1347 C C   . LYS A 1 233 ? 148.960 160.530 227.909 1.00 107.87 ? 233 LYS A C   1 
ATOM   1348 O O   . LYS A 1 233 ? 149.730 160.890 228.803 1.00 107.87 ? 233 LYS A O   1 
ATOM   1349 C CB  . LYS A 1 233 ? 149.262 161.398 225.581 1.00 107.87 ? 233 LYS A CB  1 
ATOM   1350 C CG  . LYS A 1 233 ? 148.895 160.209 224.705 1.00 107.87 ? 233 LYS A CG  1 
ATOM   1351 C CD  . LYS A 1 233 ? 149.989 159.911 223.695 1.00 107.87 ? 233 LYS A CD  1 
ATOM   1352 C CE  . LYS A 1 233 ? 151.103 159.087 224.324 1.00 107.87 ? 233 LYS A CE  1 
ATOM   1353 N NZ  . LYS A 1 233 ? 152.418 159.313 223.663 1.00 107.87 ? 233 LYS A NZ  1 
ATOM   1354 N N   . GLU A 1 234 ? 148.523 159.278 227.793 1.00 108.05 ? 234 GLU A N   1 
ATOM   1355 C CA  . GLU A 1 234 ? 148.978 158.245 228.712 1.00 108.05 ? 234 GLU A CA  1 
ATOM   1356 C C   . GLU A 1 234 ? 150.467 157.986 228.524 1.00 108.05 ? 234 GLU A C   1 
ATOM   1357 O O   . GLU A 1 234 ? 150.966 157.924 227.397 1.00 108.05 ? 234 GLU A O   1 
ATOM   1358 C CB  . GLU A 1 234 ? 148.185 156.957 228.493 1.00 108.05 ? 234 GLU A CB  1 
ATOM   1359 C CG  . GLU A 1 234 ? 146.682 157.124 228.646 1.00 108.05 ? 234 GLU A CG  1 
ATOM   1360 C CD  . GLU A 1 234 ? 146.272 157.430 230.072 1.00 108.05 ? 234 GLU A CD  1 
ATOM   1361 O OE1 . GLU A 1 234 ? 146.890 156.871 231.002 1.00 108.05 ? 234 GLU A OE1 1 
ATOM   1362 O OE2 . GLU A 1 234 ? 145.335 158.234 230.262 1.00 108.05 ? 234 GLU A OE2 1 
ATOM   1363 N N   . ARG A 1 235 ? 151.176 157.837 229.638 1.00 100.01 ? 235 ARG A N   1 
ATOM   1364 C CA  . ARG A 1 235 ? 152.614 157.610 229.584 1.00 100.01 ? 235 ARG A CA  1 
ATOM   1365 C C   . ARG A 1 235 ? 152.908 156.202 229.082 1.00 100.01 ? 235 ARG A C   1 
ATOM   1366 O O   . ARG A 1 235 ? 152.144 155.266 229.330 1.00 100.01 ? 235 ARG A O   1 
ATOM   1367 C CB  . ARG A 1 235 ? 153.238 157.814 230.964 1.00 100.01 ? 235 ARG A CB  1 
ATOM   1368 C CG  . ARG A 1 235 ? 153.237 159.257 231.466 1.00 100.01 ? 235 ARG A CG  1 
ATOM   1369 C CD  . ARG A 1 235 ? 153.142 160.273 230.339 1.00 100.01 ? 235 ARG A CD  1 
ATOM   1370 N NE  . ARG A 1 235 ? 153.178 161.640 230.844 1.00 100.01 ? 235 ARG A NE  1 
ATOM   1371 C CZ  . ARG A 1 235 ? 153.100 162.720 230.080 1.00 100.01 ? 235 ARG A CZ  1 
ATOM   1372 N NH1 . ARG A 1 235 ? 152.985 162.631 228.766 1.00 100.01 ? 235 ARG A NH1 1 
ATOM   1373 N NH2 . ARG A 1 235 ? 153.135 163.921 230.651 1.00 100.01 ? 235 ARG A NH2 1 
ATOM   1374 N N   . MET A 1 236 ? 154.019 156.054 228.369 1.00 96.44  ? 236 MET A N   1 
ATOM   1375 C CA  . MET A 1 236 ? 154.441 154.765 227.848 1.00 96.44  ? 236 MET A CA  1 
ATOM   1376 C C   . MET A 1 236 ? 155.575 154.192 228.695 1.00 96.44  ? 236 MET A C   1 
ATOM   1377 O O   . MET A 1 236 ? 155.981 154.759 229.712 1.00 96.44  ? 236 MET A O   1 
ATOM   1378 C CB  . MET A 1 236 ? 154.862 154.885 226.383 1.00 96.44  ? 236 MET A CB  1 
ATOM   1379 C CG  . MET A 1 236 ? 153.728 155.212 225.430 1.00 96.44  ? 236 MET A CG  1 
ATOM   1380 S SD  . MET A 1 236 ? 154.289 155.346 223.723 1.00 96.44  ? 236 MET A SD  1 
ATOM   1381 C CE  . MET A 1 236 ? 152.769 155.822 222.906 1.00 96.44  ? 236 MET A CE  1 
ATOM   1382 N N   . LYS A 1 237 ? 156.084 153.040 228.268 1.00 92.35  ? 237 LYS A N   1 
ATOM   1383 C CA  . LYS A 1 237 ? 157.202 152.370 228.917 1.00 92.35  ? 237 LYS A CA  1 
ATOM   1384 C C   . LYS A 1 237 ? 158.425 152.454 228.017 1.00 92.35  ? 237 LYS A C   1 
ATOM   1385 O O   . LYS A 1 237 ? 158.328 152.209 226.810 1.00 92.35  ? 237 LYS A O   1 
ATOM   1386 C CB  . LYS A 1 237 ? 156.871 150.907 229.214 1.00 92.35  ? 237 LYS A CB  1 
ATOM   1387 C CG  . LYS A 1 237 ? 157.983 150.157 229.931 1.00 92.35  ? 237 LYS A CG  1 
ATOM   1388 C CD  . LYS A 1 237 ? 157.553 148.748 230.304 1.00 92.35  ? 237 LYS A CD  1 
ATOM   1389 C CE  . LYS A 1 237 ? 157.492 147.853 229.076 1.00 92.35  ? 237 LYS A CE  1 
ATOM   1390 N NZ  . LYS A 1 237 ? 157.187 146.440 229.432 1.00 92.35  ? 237 LYS A NZ  1 
ATOM   1391 N N   . LEU A 1 238 ? 159.570 152.793 228.601 1.00 87.81  ? 238 LEU A N   1 
ATOM   1392 C CA  . LEU A 1 238 ? 160.804 152.941 227.845 1.00 87.81  ? 238 LEU A CA  1 
ATOM   1393 C C   . LEU A 1 238 ? 161.484 151.591 227.655 1.00 87.81  ? 238 LEU A C   1 
ATOM   1394 O O   . LEU A 1 238 ? 161.606 150.802 228.596 1.00 87.81  ? 238 LEU A O   1 
ATOM   1395 C CB  . LEU A 1 238 ? 161.753 153.912 228.550 1.00 87.81  ? 238 LEU A CB  1 
ATOM   1396 C CG  . LEU A 1 238 ? 163.140 154.084 227.926 1.00 87.81  ? 238 LEU A CG  1 
ATOM   1397 C CD1 . LEU A 1 238 ? 163.117 155.127 226.823 1.00 87.81  ? 238 LEU A CD1 1 
ATOM   1398 C CD2 . LEU A 1 238 ? 164.160 154.448 228.989 1.00 87.81  ? 238 LEU A CD2 1 
ATOM   1399 N N   . ASP A 1 239 ? 161.924 151.334 226.424 1.00 88.50  ? 239 ASP A N   1 
ATOM   1400 C CA  . ASP A 1 239 ? 162.647 150.110 226.082 1.00 88.50  ? 239 ASP A CA  1 
ATOM   1401 C C   . ASP A 1 239 ? 164.115 150.331 226.421 1.00 88.50  ? 239 ASP A C   1 
ATOM   1402 O O   . ASP A 1 239 ? 164.892 150.846 225.616 1.00 88.50  ? 239 ASP A O   1 
ATOM   1403 C CB  . ASP A 1 239 ? 162.446 149.765 224.612 1.00 88.50  ? 239 ASP A CB  1 
ATOM   1404 C CG  . ASP A 1 239 ? 163.248 148.556 224.179 1.00 88.50  ? 239 ASP A CG  1 
ATOM   1405 O OD1 . ASP A 1 239 ? 163.294 147.568 224.939 1.00 88.50  ? 239 ASP A OD1 1 
ATOM   1406 O OD2 . ASP A 1 239 ? 163.828 148.594 223.074 1.00 88.50  ? 239 ASP A OD2 1 
ATOM   1407 N N   . ALA A 1 240 ? 164.498 149.940 227.639 1.00 87.55  ? 240 ALA A N   1 
ATOM   1408 C CA  . ALA A 1 240 ? 165.844 150.228 228.125 1.00 87.55  ? 240 ALA A CA  1 
ATOM   1409 C C   . ALA A 1 240 ? 166.907 149.472 227.337 1.00 87.55  ? 240 ALA A C   1 
ATOM   1410 O O   . ALA A 1 240 ? 167.951 150.039 226.994 1.00 87.55  ? 240 ALA A O   1 
ATOM   1411 C CB  . ALA A 1 240 ? 165.945 149.895 229.612 1.00 87.55  ? 240 ALA A CB  1 
ATOM   1412 N N   . THR A 1 241 ? 166.666 148.191 227.048 1.00 86.44  ? 241 THR A N   1 
ATOM   1413 C CA  . THR A 1 241 ? 167.675 147.379 226.373 1.00 86.44  ? 241 THR A CA  1 
ATOM   1414 C C   . THR A 1 241 ? 167.969 147.911 224.975 1.00 86.44  ? 241 THR A C   1 
ATOM   1415 O O   . THR A 1 241 ? 169.134 148.099 224.598 1.00 86.44  ? 241 THR A O   1 
ATOM   1416 C CB  . THR A 1 241 ? 167.212 145.924 226.306 1.00 86.44  ? 241 THR A CB  1 
ATOM   1417 O OG1 . THR A 1 241 ? 166.886 145.464 227.624 1.00 86.44  ? 241 THR A OG1 1 
ATOM   1418 C CG2 . THR A 1 241 ? 168.303 145.042 225.725 1.00 86.44  ? 241 THR A CG2 1 
ATOM   1419 N N   . GLY A 1 242 ? 166.919 148.160 224.192 1.00 85.61  ? 242 GLY A N   1 
ATOM   1420 C CA  . GLY A 1 242 ? 167.117 148.690 222.855 1.00 85.61  ? 242 GLY A CA  1 
ATOM   1421 C C   . GLY A 1 242 ? 167.753 150.065 222.864 1.00 85.61  ? 242 GLY A C   1 
ATOM   1422 O O   . GLY A 1 242 ? 168.605 150.369 222.026 1.00 85.61  ? 242 GLY A O   1 
ATOM   1423 N N   . ALA A 1 243 ? 167.351 150.914 223.812 1.00 83.12  ? 243 ALA A N   1 
ATOM   1424 C CA  . ALA A 1 243 ? 167.933 152.247 223.910 1.00 83.12  ? 243 ALA A CA  1 
ATOM   1425 C C   . ALA A 1 243 ? 169.425 152.173 224.206 1.00 83.12  ? 243 ALA A C   1 
ATOM   1426 O O   . ALA A 1 243 ? 170.229 152.873 223.581 1.00 83.12  ? 243 ALA A O   1 
ATOM   1427 C CB  . ALA A 1 243 ? 167.209 153.058 224.983 1.00 83.12  ? 243 ALA A CB  1 
ATOM   1428 N N   . ILE A 1 244 ? 169.814 151.315 225.152 1.00 82.16  ? 244 ILE A N   1 
ATOM   1429 C CA  . ILE A 1 244 ? 171.226 151.175 225.497 1.00 82.16  ? 244 ILE A CA  1 
ATOM   1430 C C   . ILE A 1 244 ? 172.017 150.641 224.309 1.00 82.16  ? 244 ILE A C   1 
ATOM   1431 O O   . ILE A 1 244 ? 173.107 151.140 223.994 1.00 82.16  ? 244 ILE A O   1 
ATOM   1432 C CB  . ILE A 1 244 ? 171.388 150.274 226.735 1.00 82.16  ? 244 ILE A CB  1 
ATOM   1433 C CG1 . ILE A 1 244 ? 170.918 151.005 227.992 1.00 82.16  ? 244 ILE A CG1 1 
ATOM   1434 C CG2 . ILE A 1 244 ? 172.832 149.835 226.892 1.00 82.16  ? 244 ILE A CG2 1 
ATOM   1435 C CD1 . ILE A 1 244 ? 171.072 150.197 229.257 1.00 82.16  ? 244 ILE A CD1 1 
ATOM   1436 N N   . LEU A 1 245 ? 171.485 149.620 223.632 1.00 83.51  ? 245 LEU A N   1 
ATOM   1437 C CA  . LEU A 1 245 ? 172.202 149.048 222.496 1.00 83.51  ? 245 LEU A CA  1 
ATOM   1438 C C   . LEU A 1 245 ? 172.359 150.062 221.369 1.00 83.51  ? 245 LEU A C   1 
ATOM   1439 O O   . LEU A 1 245 ? 173.434 150.167 220.765 1.00 83.51  ? 245 LEU A O   1 
ATOM   1440 C CB  . LEU A 1 245 ? 171.484 147.793 222.002 1.00 83.51  ? 245 LEU A CB  1 
ATOM   1441 C CG  . LEU A 1 245 ? 171.644 146.563 222.896 1.00 83.51  ? 245 LEU A CG  1 
ATOM   1442 C CD1 . LEU A 1 245 ? 170.835 145.396 222.362 1.00 83.51  ? 245 LEU A CD1 1 
ATOM   1443 C CD2 . LEU A 1 245 ? 173.111 146.187 223.027 1.00 83.51  ? 245 LEU A CD2 1 
ATOM   1444 N N   . ALA A 1 246 ? 171.301 150.823 221.075 1.00 81.74  ? 246 ALA A N   1 
ATOM   1445 C CA  . ALA A 1 246 ? 171.382 151.834 220.025 1.00 81.74  ? 246 ALA A CA  1 
ATOM   1446 C C   . ALA A 1 246 ? 172.370 152.933 220.389 1.00 81.74  ? 246 ALA A C   1 
ATOM   1447 O O   . ALA A 1 246 ? 173.143 153.389 219.537 1.00 81.74  ? 246 ALA A O   1 
ATOM   1448 C CB  . ALA A 1 246 ? 169.998 152.424 219.758 1.00 81.74  ? 246 ALA A CB  1 
ATOM   1449 N N   . THR A 1 247 ? 172.361 153.372 221.650 1.00 79.59  ? 247 THR A N   1 
ATOM   1450 C CA  . THR A 1 247 ? 173.307 154.393 222.084 1.00 79.59  ? 247 THR A CA  1 
ATOM   1451 C C   . THR A 1 247 ? 174.740 153.909 221.922 1.00 79.59  ? 247 THR A C   1 
ATOM   1452 O O   . THR A 1 247 ? 175.595 154.627 221.389 1.00 79.59  ? 247 THR A O   1 
ATOM   1453 C CB  . THR A 1 247 ? 173.033 154.776 223.538 1.00 79.59  ? 247 THR A CB  1 
ATOM   1454 O OG1 . THR A 1 247 ? 171.671 155.198 223.674 1.00 79.59  ? 247 THR A OG1 1 
ATOM   1455 C CG2 . THR A 1 247 ? 173.949 155.901 223.974 1.00 79.59  ? 247 THR A CG2 1 
ATOM   1456 N N   . LEU A 1 248 ? 175.019 152.680 222.365 1.00 81.09  ? 248 LEU A N   1 
ATOM   1457 C CA  . LEU A 1 248 ? 176.372 152.147 222.250 1.00 81.09  ? 248 LEU A CA  1 
ATOM   1458 C C   . LEU A 1 248 ? 176.793 152.020 220.792 1.00 81.09  ? 248 LEU A C   1 
ATOM   1459 O O   . LEU A 1 248 ? 177.911 152.402 220.426 1.00 81.09  ? 248 LEU A O   1 
ATOM   1460 C CB  . LEU A 1 248 ? 176.468 150.797 222.959 1.00 81.09  ? 248 LEU A CB  1 
ATOM   1461 C CG  . LEU A 1 248 ? 177.669 149.922 222.597 1.00 81.09  ? 248 LEU A CG  1 
ATOM   1462 C CD1 . LEU A 1 248 ? 178.963 150.538 223.107 1.00 81.09  ? 248 LEU A CD1 1 
ATOM   1463 C CD2 . LEU A 1 248 ? 177.493 148.518 223.146 1.00 81.09  ? 248 LEU A CD2 1 
ATOM   1464 N N   . ALA A 1 249 ? 175.906 151.501 219.939 1.00 82.00  ? 249 ALA A N   1 
ATOM   1465 C CA  . ALA A 1 249 ? 176.250 151.321 218.533 1.00 82.00  ? 249 ALA A CA  1 
ATOM   1466 C C   . ALA A 1 249 ? 176.539 152.655 217.859 1.00 82.00  ? 249 ALA A C   1 
ATOM   1467 O O   . ALA A 1 249 ? 177.547 152.804 217.157 1.00 82.00  ? 249 ALA A O   1 
ATOM   1468 C CB  . ALA A 1 249 ? 175.121 150.588 217.808 1.00 82.00  ? 249 ALA A CB  1 
ATOM   1469 N N   . CYS A 1 250 ? 175.664 153.643 218.064 1.00 81.01  ? 250 CYS A N   1 
ATOM   1470 C CA  . CYS A 1 250 ? 175.855 154.938 217.420 1.00 81.01  ? 250 CYS A CA  1 
ATOM   1471 C C   . CYS A 1 250 ? 177.109 155.635 217.931 1.00 81.01  ? 250 CYS A C   1 
ATOM   1472 O O   . CYS A 1 250 ? 177.868 156.212 217.141 1.00 81.01  ? 250 CYS A O   1 
ATOM   1473 C CB  . CYS A 1 250 ? 174.622 155.814 217.633 1.00 81.01  ? 250 CYS A CB  1 
ATOM   1474 S SG  . CYS A 1 250 ? 173.122 155.183 216.851 1.00 81.01  ? 250 CYS A SG  1 
ATOM   1475 N N   . THR A 1 251 ? 177.349 155.595 219.245 1.00 82.37  ? 251 THR A N   1 
ATOM   1476 C CA  . THR A 1 251 ? 178.541 156.233 219.791 1.00 82.37  ? 251 THR A CA  1 
ATOM   1477 C C   . THR A 1 251 ? 179.809 155.580 219.259 1.00 82.37  ? 251 THR A C   1 
ATOM   1478 O O   . THR A 1 251 ? 180.761 156.274 218.882 1.00 82.37  ? 251 THR A O   1 
ATOM   1479 C CB  . THR A 1 251 ? 178.512 156.180 221.316 1.00 82.37  ? 251 THR A CB  1 
ATOM   1480 O OG1 . THR A 1 251 ? 177.281 156.736 221.790 1.00 82.37  ? 251 THR A OG1 1 
ATOM   1481 C CG2 . THR A 1 251 ? 179.671 156.970 221.895 1.00 82.37  ? 251 THR A CG2 1 
ATOM   1482 N N   . ALA A 1 252 ? 179.840 154.244 219.209 1.00 86.67  ? 252 ALA A N   1 
ATOM   1483 C CA  . ALA A 1 252 ? 181.017 153.557 218.690 1.00 86.67  ? 252 ALA A CA  1 
ATOM   1484 C C   . ALA A 1 252 ? 181.238 153.873 217.217 1.00 86.67  ? 252 ALA A C   1 
ATOM   1485 O O   . ALA A 1 252 ? 182.377 154.085 216.786 1.00 86.67  ? 252 ALA A O   1 
ATOM   1486 C CB  . ALA A 1 252 ? 180.884 152.051 218.903 1.00 86.67  ? 252 ALA A CB  1 
ATOM   1487 N N   . ALA A 1 253 ? 180.161 153.912 216.428 1.00 87.86  ? 253 ALA A N   1 
ATOM   1488 C CA  . ALA A 1 253 ? 180.302 154.232 215.011 1.00 87.86  ? 253 ALA A CA  1 
ATOM   1489 C C   . ALA A 1 253 ? 180.844 155.642 214.812 1.00 87.86  ? 253 ALA A C   1 
ATOM   1490 O O   . ALA A 1 253 ? 181.746 155.859 213.991 1.00 87.86  ? 253 ALA A O   1 
ATOM   1491 C CB  . ALA A 1 253 ? 178.960 154.069 214.300 1.00 87.86  ? 253 ALA A CB  1 
ATOM   1492 N N   . VAL A 1 254 ? 180.314 156.613 215.560 1.00 87.13  ? 254 VAL A N   1 
ATOM   1493 C CA  . VAL A 1 254 ? 180.782 157.990 215.425 1.00 87.13  ? 254 VAL A CA  1 
ATOM   1494 C C   . VAL A 1 254 ? 182.243 158.101 215.842 1.00 87.13  ? 254 VAL A C   1 
ATOM   1495 O O   . VAL A 1 254 ? 183.049 158.756 215.167 1.00 87.13  ? 254 VAL A O   1 
ATOM   1496 C CB  . VAL A 1 254 ? 179.884 158.944 216.235 1.00 87.13  ? 254 VAL A CB  1 
ATOM   1497 C CG1 . VAL A 1 254 ? 180.515 160.318 216.325 1.00 87.13  ? 254 VAL A CG1 1 
ATOM   1498 C CG2 . VAL A 1 254 ? 178.510 159.036 215.601 1.00 87.13  ? 254 VAL A CG2 1 
ATOM   1499 N N   . PHE A 1 255 ? 182.612 157.457 216.953 1.00 93.97  ? 255 PHE A N   1 
ATOM   1500 C CA  . PHE A 1 255 ? 183.993 157.515 217.419 1.00 93.97  ? 255 PHE A CA  1 
ATOM   1501 C C   . PHE A 1 255 ? 184.945 156.894 216.404 1.00 93.97  ? 255 PHE A C   1 
ATOM   1502 O O   . PHE A 1 255 ? 186.019 157.441 216.128 1.00 93.97  ? 255 PHE A O   1 
ATOM   1503 C CB  . PHE A 1 255 ? 184.116 156.812 218.771 1.00 93.97  ? 255 PHE A CB  1 
ATOM   1504 C CG  . PHE A 1 255 ? 185.498 156.855 219.351 1.00 93.97  ? 255 PHE A CG  1 
ATOM   1505 C CD1 . PHE A 1 255 ? 185.984 158.014 219.930 1.00 93.97  ? 255 PHE A CD1 1 
ATOM   1506 C CD2 . PHE A 1 255 ? 186.312 155.737 219.316 1.00 93.97  ? 255 PHE A CD2 1 
ATOM   1507 C CE1 . PHE A 1 255 ? 187.256 158.055 220.465 1.00 93.97  ? 255 PHE A CE1 1 
ATOM   1508 C CE2 . PHE A 1 255 ? 187.585 155.772 219.849 1.00 93.97  ? 255 PHE A CE2 1 
ATOM   1509 C CZ  . PHE A 1 255 ? 188.057 156.933 220.424 1.00 93.97  ? 255 PHE A CZ  1 
ATOM   1510 N N   . ALA A 1 256 ? 184.568 155.744 215.840 1.00 97.20  ? 256 ALA A N   1 
ATOM   1511 C CA  . ALA A 1 256 ? 185.420 155.098 214.848 1.00 97.20  ? 256 ALA A CA  1 
ATOM   1512 C C   . ALA A 1 256 ? 185.574 155.963 213.605 1.00 97.20  ? 256 ALA A C   1 
ATOM   1513 O O   . ALA A 1 256 ? 186.686 156.126 213.088 1.00 97.20  ? 256 ALA A O   1 
ATOM   1514 C CB  . ALA A 1 256 ? 184.852 153.727 214.483 1.00 97.20  ? 256 ALA A CB  1 
ATOM   1515 N N   . PHE A 1 257 ? 184.470 156.532 213.113 1.00 97.39  ? 257 PHE A N   1 
ATOM   1516 C CA  . PHE A 1 257 ? 184.545 157.375 211.925 1.00 97.39  ? 257 PHE A CA  1 
ATOM   1517 C C   . PHE A 1 257 ? 185.369 158.631 212.180 1.00 97.39  ? 257 PHE A C   1 
ATOM   1518 O O   . PHE A 1 257 ? 186.016 159.142 211.260 1.00 97.39  ? 257 PHE A O   1 
ATOM   1519 C CB  . PHE A 1 257 ? 183.136 157.739 211.454 1.00 97.39  ? 257 PHE A CB  1 
ATOM   1520 C CG  . PHE A 1 257 ? 183.100 158.477 210.144 1.00 97.39  ? 257 PHE A CG  1 
ATOM   1521 C CD1 . PHE A 1 257 ? 183.025 157.785 208.947 1.00 97.39  ? 257 PHE A CD1 1 
ATOM   1522 C CD2 . PHE A 1 257 ? 183.120 159.862 210.108 1.00 97.39  ? 257 PHE A CD2 1 
ATOM   1523 C CE1 . PHE A 1 257 ? 182.986 158.460 207.740 1.00 97.39  ? 257 PHE A CE1 1 
ATOM   1524 C CE2 . PHE A 1 257 ? 183.082 160.542 208.905 1.00 97.39  ? 257 PHE A CE2 1 
ATOM   1525 C CZ  . PHE A 1 257 ? 183.014 159.839 207.720 1.00 97.39  ? 257 PHE A CZ  1 
ATOM   1526 N N   . SER A 1 258 ? 185.357 159.145 213.412 1.00 102.62 ? 258 SER A N   1 
ATOM   1527 C CA  . SER A 1 258 ? 186.146 160.332 213.720 1.00 102.62 ? 258 SER A CA  1 
ATOM   1528 C C   . SER A 1 258 ? 187.628 160.012 213.876 1.00 102.62 ? 258 SER A C   1 
ATOM   1529 O O   . SER A 1 258 ? 188.481 160.800 213.455 1.00 102.62 ? 258 SER A O   1 
ATOM   1530 C CB  . SER A 1 258 ? 185.619 161.000 214.988 1.00 102.62 ? 258 SER A CB  1 
ATOM   1531 O OG  . SER A 1 258 ? 186.399 162.135 215.315 1.00 102.62 ? 258 SER A OG  1 
ATOM   1532 N N   . ILE A 1 259 ? 187.956 158.868 214.477 1.00 107.42 ? 259 ILE A N   1 
ATOM   1533 C CA  . ILE A 1 259 ? 189.353 158.540 214.750 1.00 107.42 ? 259 ILE A CA  1 
ATOM   1534 C C   . ILE A 1 259 ? 190.057 157.903 213.554 1.00 107.42 ? 259 ILE A C   1 
ATOM   1535 O O   . ILE A 1 259 ? 191.292 157.975 213.467 1.00 107.42 ? 259 ILE A O   1 
ATOM   1536 C CB  . ILE A 1 259 ? 189.440 157.634 215.994 1.00 107.42 ? 259 ILE A CB  1 
ATOM   1537 C CG1 . ILE A 1 259 ? 188.845 158.353 217.204 1.00 107.42 ? 259 ILE A CG1 1 
ATOM   1538 C CG2 . ILE A 1 259 ? 190.874 157.251 216.315 1.00 107.42 ? 259 ILE A CG2 1 
ATOM   1539 C CD1 . ILE A 1 259 ? 189.554 159.643 217.551 1.00 107.42 ? 259 ILE A CD1 1 
ATOM   1540 N N   . GLY A 1 260 ? 189.312 157.321 212.614 1.00 114.09 ? 260 GLY A N   1 
ATOM   1541 C CA  . GLY A 1 260 ? 189.890 156.670 211.461 1.00 114.09 ? 260 GLY A CA  1 
ATOM   1542 C C   . GLY A 1 260 ? 190.950 157.468 210.726 1.00 114.09 ? 260 GLY A C   1 
ATOM   1543 O O   . GLY A 1 260 ? 192.119 157.073 210.672 1.00 114.09 ? 260 GLY A O   1 
ATOM   1544 N N   . PRO A 1 261 ? 190.564 158.605 210.135 1.00 115.76 ? 261 PRO A N   1 
ATOM   1545 C CA  . PRO A 1 261 ? 191.539 159.375 209.340 1.00 115.76 ? 261 PRO A CA  1 
ATOM   1546 C C   . PRO A 1 261 ? 192.763 159.822 210.123 1.00 115.76 ? 261 PRO A C   1 
ATOM   1547 O O   . PRO A 1 261 ? 193.866 159.861 209.564 1.00 115.76 ? 261 PRO A O   1 
ATOM   1548 C CB  . PRO A 1 261 ? 190.713 160.571 208.846 1.00 115.76 ? 261 PRO A CB  1 
ATOM   1549 C CG  . PRO A 1 261 ? 189.304 160.095 208.874 1.00 115.76 ? 261 PRO A CG  1 
ATOM   1550 C CD  . PRO A 1 261 ? 189.211 159.179 210.054 1.00 115.76 ? 261 PRO A CD  1 
ATOM   1551 N N   . GLU A 1 262 ? 192.604 160.166 211.402 1.00 115.97 ? 262 GLU A N   1 
ATOM   1552 C CA  . GLU A 1 262 ? 193.737 160.660 212.178 1.00 115.97 ? 262 GLU A CA  1 
ATOM   1553 C C   . GLU A 1 262 ? 194.754 159.555 212.442 1.00 115.97 ? 262 GLU A C   1 
ATOM   1554 O O   . GLU A 1 262 ? 195.957 159.740 212.224 1.00 115.97 ? 262 GLU A O   1 
ATOM   1555 C CB  . GLU A 1 262 ? 193.246 161.266 213.493 1.00 115.97 ? 262 GLU A CB  1 
ATOM   1556 C CG  . GLU A 1 262 ? 192.247 162.397 213.318 1.00 115.97 ? 262 GLU A CG  1 
ATOM   1557 C CD  . GLU A 1 262 ? 191.642 162.848 214.633 1.00 115.97 ? 262 GLU A CD  1 
ATOM   1558 O OE1 . GLU A 1 262 ? 192.005 162.278 215.683 1.00 115.97 ? 262 GLU A OE1 1 
ATOM   1559 O OE2 . GLU A 1 262 ? 190.799 163.769 214.616 1.00 115.97 ? 262 GLU A OE2 1 
ATOM   1560 N N   . LYS A 1 263 ? 194.290 158.397 212.911 1.00 118.01 ? 263 LYS A N   1 
ATOM   1561 C CA  . LYS A 1 263 ? 195.197 157.295 213.220 1.00 118.01 ? 263 LYS A CA  1 
ATOM   1562 C C   . LYS A 1 263 ? 195.496 156.462 211.978 1.00 118.01 ? 263 LYS A C   1 
ATOM   1563 O O   . LYS A 1 263 ? 196.655 156.318 211.574 1.00 118.01 ? 263 LYS A O   1 
ATOM   1564 C CB  . LYS A 1 263 ? 194.600 156.418 214.323 1.00 118.01 ? 263 LYS A CB  1 
ATOM   1565 C CG  . LYS A 1 263 ? 194.482 157.101 215.676 1.00 118.01 ? 263 LYS A CG  1 
ATOM   1566 C CD  . LYS A 1 263 ? 195.757 156.960 216.489 1.00 118.01 ? 263 LYS A CD  1 
ATOM   1567 C CE  . LYS A 1 263 ? 195.895 158.093 217.493 1.00 118.01 ? 263 LYS A CE  1 
ATOM   1568 N NZ  . LYS A 1 263 ? 196.599 157.657 218.731 1.00 118.01 ? 263 LYS A NZ  1 
ATOM   1569 N N   . GLY A 1 264 ? 194.464 155.910 211.366 1.00 122.22 ? 264 GLY A N   1 
ATOM   1570 C CA  . GLY A 1 264 ? 194.625 155.097 210.177 1.00 122.22 ? 264 GLY A CA  1 
ATOM   1571 C C   . GLY A 1 264 ? 193.504 154.083 210.081 1.00 122.22 ? 264 GLY A C   1 
ATOM   1572 O O   . GLY A 1 264 ? 192.714 153.901 211.003 1.00 122.22 ? 264 GLY A O   1 
ATOM   1573 N N   . TRP A 1 265 ? 193.456 153.417 208.930 1.00 125.66 ? 265 TRP A N   1 
ATOM   1574 C CA  . TRP A 1 265 ? 192.458 152.389 208.673 1.00 125.66 ? 265 TRP A CA  1 
ATOM   1575 C C   . TRP A 1 265 ? 192.902 151.011 209.140 1.00 125.66 ? 265 TRP A C   1 
ATOM   1576 O O   . TRP A 1 265 ? 192.119 150.060 209.057 1.00 125.66 ? 265 TRP A O   1 
ATOM   1577 C CB  . TRP A 1 265 ? 192.117 152.344 207.179 1.00 125.66 ? 265 TRP A CB  1 
ATOM   1578 C CG  . TRP A 1 265 ? 191.715 153.671 206.604 1.00 125.66 ? 265 TRP A CG  1 
ATOM   1579 C CD1 . TRP A 1 265 ? 192.263 154.290 205.518 1.00 125.66 ? 265 TRP A CD1 1 
ATOM   1580 C CD2 . TRP A 1 265 ? 190.678 154.541 207.079 1.00 125.66 ? 265 TRP A CD2 1 
ATOM   1581 N NE1 . TRP A 1 265 ? 191.636 155.490 205.289 1.00 125.66 ? 265 TRP A NE1 1 
ATOM   1582 C CE2 . TRP A 1 265 ? 190.659 155.668 206.232 1.00 125.66 ? 265 TRP A CE2 1 
ATOM   1583 C CE3 . TRP A 1 265 ? 189.764 154.478 208.136 1.00 125.66 ? 265 TRP A CE3 1 
ATOM   1584 C CZ2 . TRP A 1 265 ? 189.764 156.720 206.410 1.00 125.66 ? 265 TRP A CZ2 1 
ATOM   1585 C CZ3 . TRP A 1 265 ? 188.878 155.523 208.310 1.00 125.66 ? 265 TRP A CZ3 1 
ATOM   1586 C CH2 . TRP A 1 265 ? 188.884 156.629 207.453 1.00 125.66 ? 265 TRP A CH2 1 
ATOM   1587 N N   . MET A 1 266 ? 194.134 150.880 209.626 1.00 126.62 ? 266 MET A N   1 
ATOM   1588 C CA  . MET A 1 266 ? 194.646 149.616 210.130 1.00 126.62 ? 266 MET A CA  1 
ATOM   1589 C C   . MET A 1 266 ? 194.916 149.643 211.626 1.00 126.62 ? 266 MET A C   1 
ATOM   1590 O O   . MET A 1 266 ? 195.457 148.667 212.160 1.00 126.62 ? 266 MET A O   1 
ATOM   1591 C CB  . MET A 1 266 ? 195.930 149.226 209.385 1.00 126.62 ? 266 MET A CB  1 
ATOM   1592 C CG  . MET A 1 266 ? 197.091 150.182 209.608 1.00 126.62 ? 266 MET A CG  1 
ATOM   1593 S SD  . MET A 1 266 ? 198.544 149.746 208.635 1.00 126.62 ? 266 MET A SD  1 
ATOM   1594 C CE  . MET A 1 266 ? 198.010 150.235 206.997 1.00 126.62 ? 266 MET A CE  1 
ATOM   1595 N N   . SER A 1 267 ? 194.566 150.726 212.313 1.00 122.68 ? 267 SER A N   1 
ATOM   1596 C CA  . SER A 1 267 ? 194.775 150.806 213.751 1.00 122.68 ? 267 SER A CA  1 
ATOM   1597 C C   . SER A 1 267 ? 193.876 149.815 214.478 1.00 122.68 ? 267 SER A C   1 
ATOM   1598 O O   . SER A 1 267 ? 192.741 149.563 214.065 1.00 122.68 ? 267 SER A O   1 
ATOM   1599 C CB  . SER A 1 267 ? 194.502 152.225 214.249 1.00 122.68 ? 267 SER A CB  1 
ATOM   1600 O OG  . SER A 1 267 ? 194.520 152.280 215.664 1.00 122.68 ? 267 SER A OG  1 
ATOM   1601 N N   . GLY A 1 268 ? 194.394 149.246 215.567 1.00 120.10 ? 268 GLY A N   1 
ATOM   1602 C CA  . GLY A 1 268 ? 193.602 148.316 216.351 1.00 120.10 ? 268 GLY A CA  1 
ATOM   1603 C C   . GLY A 1 268 ? 192.403 148.964 217.011 1.00 120.10 ? 268 GLY A C   1 
ATOM   1604 O O   . GLY A 1 268 ? 191.344 148.339 217.132 1.00 120.10 ? 268 GLY A O   1 
ATOM   1605 N N   . ILE A 1 269 ? 192.547 150.219 217.445 1.00 118.10 ? 269 ILE A N   1 
ATOM   1606 C CA  . ILE A 1 269 ? 191.449 150.916 218.110 1.00 118.10 ? 269 ILE A CA  1 
ATOM   1607 C C   . ILE A 1 269 ? 190.273 151.099 217.159 1.00 118.10 ? 269 ILE A C   1 
ATOM   1608 O O   . ILE A 1 269 ? 189.117 150.869 217.531 1.00 118.10 ? 269 ILE A O   1 
ATOM   1609 C CB  . ILE A 1 269 ? 191.939 152.263 218.673 1.00 118.10 ? 269 ILE A CB  1 
ATOM   1610 C CG1 . ILE A 1 269 ? 192.938 152.035 219.809 1.00 118.10 ? 269 ILE A CG1 1 
ATOM   1611 C CG2 . ILE A 1 269 ? 190.766 153.101 219.155 1.00 118.10 ? 269 ILE A CG2 1 
ATOM   1612 C CD1 . ILE A 1 269 ? 193.585 153.303 220.315 1.00 118.10 ? 269 ILE A CD1 1 
ATOM   1613 N N   . THR A 1 270 ? 190.548 151.516 215.921 1.00 115.77 ? 270 THR A N   1 
ATOM   1614 C CA  . THR A 1 270 ? 189.472 151.733 214.958 1.00 115.77 ? 270 THR A CA  1 
ATOM   1615 C C   . THR A 1 270 ? 188.753 150.431 214.624 1.00 115.77 ? 270 THR A C   1 
ATOM   1616 O O   . THR A 1 270 ? 187.518 150.395 214.552 1.00 115.77 ? 270 THR A O   1 
ATOM   1617 C CB  . THR A 1 270 ? 190.026 152.377 213.688 1.00 115.77 ? 270 THR A CB  1 
ATOM   1618 O OG1 . THR A 1 270 ? 190.755 153.561 214.031 1.00 115.77 ? 270 THR A OG1 1 
ATOM   1619 C CG2 . THR A 1 270 ? 188.898 152.745 212.740 1.00 115.77 ? 270 THR A CG2 1 
ATOM   1620 N N   . ILE A 1 271 ? 189.510 149.351 214.415 1.00 115.21 ? 271 ILE A N   1 
ATOM   1621 C CA  . ILE A 1 271 ? 188.895 148.063 214.105 1.00 115.21 ? 271 ILE A CA  1 
ATOM   1622 C C   . ILE A 1 271 ? 188.056 147.577 215.279 1.00 115.21 ? 271 ILE A C   1 
ATOM   1623 O O   . ILE A 1 271 ? 186.942 147.070 215.097 1.00 115.21 ? 271 ILE A O   1 
ATOM   1624 C CB  . ILE A 1 271 ? 189.969 147.035 213.708 1.00 115.21 ? 271 ILE A CB  1 
ATOM   1625 C CG1 . ILE A 1 271 ? 190.787 147.552 212.524 1.00 115.21 ? 271 ILE A CG1 1 
ATOM   1626 C CG2 . ILE A 1 271 ? 189.329 145.700 213.364 1.00 115.21 ? 271 ILE A CG2 1 
ATOM   1627 C CD1 . ILE A 1 271 ? 189.963 147.812 211.284 1.00 115.21 ? 271 ILE A CD1 1 
ATOM   1628 N N   . GLY A 1 272 ? 188.574 147.722 216.502 1.00 111.34 ? 272 GLY A N   1 
ATOM   1629 C CA  . GLY A 1 272 ? 187.801 147.327 217.668 1.00 111.34 ? 272 GLY A CA  1 
ATOM   1630 C C   . GLY A 1 272 ? 186.525 148.132 217.822 1.00 111.34 ? 272 GLY A C   1 
ATOM   1631 O O   . GLY A 1 272 ? 185.468 147.585 218.146 1.00 111.34 ? 272 GLY A O   1 
ATOM   1632 N N   . SER A 1 273 ? 186.606 149.445 217.588 1.00 107.06 ? 273 SER A N   1 
ATOM   1633 C CA  . SER A 1 273 ? 185.419 150.289 217.675 1.00 107.06 ? 273 SER A CA  1 
ATOM   1634 C C   . SER A 1 273 ? 184.384 149.895 216.630 1.00 107.06 ? 273 SER A C   1 
ATOM   1635 O O   . SER A 1 273 ? 183.187 149.816 216.930 1.00 107.06 ? 273 SER A O   1 
ATOM   1636 C CB  . SER A 1 273 ? 185.813 151.757 217.518 1.00 107.06 ? 273 SER A CB  1 
ATOM   1637 O OG  . SER A 1 273 ? 184.690 152.605 217.666 1.00 107.06 ? 273 SER A OG  1 
ATOM   1638 N N   . GLY A 1 274 ? 184.826 149.640 215.397 1.00 106.46 ? 274 GLY A N   1 
ATOM   1639 C CA  . GLY A 1 274 ? 183.896 149.200 214.369 1.00 106.46 ? 274 GLY A CA  1 
ATOM   1640 C C   . GLY A 1 274 ? 183.264 147.860 214.692 1.00 106.46 ? 274 GLY A C   1 
ATOM   1641 O O   . GLY A 1 274 ? 182.074 147.646 214.440 1.00 106.46 ? 274 GLY A O   1 
ATOM   1642 N N   . LEU A 1 275 ? 184.051 146.940 215.254 1.00 106.88 ? 275 LEU A N   1 
ATOM   1643 C CA  . LEU A 1 275 ? 183.512 145.641 215.640 1.00 106.88 ? 275 LEU A CA  1 
ATOM   1644 C C   . LEU A 1 275 ? 182.467 145.782 216.739 1.00 106.88 ? 275 LEU A C   1 
ATOM   1645 O O   . LEU A 1 275 ? 181.415 145.133 216.693 1.00 106.88 ? 275 LEU A O   1 
ATOM   1646 C CB  . LEU A 1 275 ? 184.646 144.721 216.091 1.00 106.88 ? 275 LEU A CB  1 
ATOM   1647 C CG  . LEU A 1 275 ? 185.486 144.090 214.979 1.00 106.88 ? 275 LEU A CG  1 
ATOM   1648 C CD1 . LEU A 1 275 ? 186.539 143.167 215.567 1.00 106.88 ? 275 LEU A CD1 1 
ATOM   1649 C CD2 . LEU A 1 275 ? 184.602 143.344 213.992 1.00 106.88 ? 275 LEU A CD2 1 
ATOM   1650 N N   . VAL A 1 276 ? 182.739 146.629 217.735 1.00 102.45 ? 276 VAL A N   1 
ATOM   1651 C CA  . VAL A 1 276 ? 181.763 146.864 218.796 1.00 102.45 ? 276 VAL A CA  1 
ATOM   1652 C C   . VAL A 1 276 ? 180.497 147.488 218.226 1.00 102.45 ? 276 VAL A C   1 
ATOM   1653 O O   . VAL A 1 276 ? 179.380 147.123 218.611 1.00 102.45 ? 276 VAL A O   1 
ATOM   1654 C CB  . VAL A 1 276 ? 182.373 147.733 219.911 1.00 102.45 ? 276 VAL A CB  1 
ATOM   1655 C CG1 . VAL A 1 276 ? 181.324 148.065 220.954 1.00 102.45 ? 276 VAL A CG1 1 
ATOM   1656 C CG2 . VAL A 1 276 ? 183.534 147.010 220.562 1.00 102.45 ? 276 VAL A CG2 1 
ATOM   1657 N N   . ALA A 1 277 ? 180.648 148.439 217.301 1.00 98.45  ? 277 ALA A N   1 
ATOM   1658 C CA  . ALA A 1 277 ? 179.479 149.059 216.686 1.00 98.45  ? 277 ALA A CA  1 
ATOM   1659 C C   . ALA A 1 277 ? 178.636 148.034 215.940 1.00 98.45  ? 277 ALA A C   1 
ATOM   1660 O O   . ALA A 1 277 ? 177.407 148.013 216.077 1.00 98.45  ? 277 ALA A O   1 
ATOM   1661 C CB  . ALA A 1 277 ? 179.913 150.180 215.744 1.00 98.45  ? 277 ALA A CB  1 
ATOM   1662 N N   . LEU A 1 278 ? 179.279 147.166 215.153 1.00 98.82  ? 278 LEU A N   1 
ATOM   1663 C CA  . LEU A 1 278 ? 178.533 146.158 214.405 1.00 98.82  ? 278 LEU A CA  1 
ATOM   1664 C C   . LEU A 1 278 ? 177.841 145.170 215.338 1.00 98.82  ? 278 LEU A C   1 
ATOM   1665 O O   . LEU A 1 278 ? 176.676 144.810 215.122 1.00 98.82  ? 278 LEU A O   1 
ATOM   1666 C CB  . LEU A 1 278 ? 179.463 145.422 213.441 1.00 98.82  ? 278 LEU A CB  1 
ATOM   1667 C CG  . LEU A 1 278 ? 178.809 144.863 212.176 1.00 98.82  ? 278 LEU A CG  1 
ATOM   1668 C CD1 . LEU A 1 278 ? 177.841 145.871 211.577 1.00 98.82  ? 278 LEU A CD1 1 
ATOM   1669 C CD2 . LEU A 1 278 ? 179.863 144.460 211.158 1.00 98.82  ? 278 LEU A CD2 1 
ATOM   1670 N N   . ALA A 1 279 ? 178.542 144.723 216.384 1.00 97.12  ? 279 ALA A N   1 
ATOM   1671 C CA  . ALA A 1 279 ? 177.940 143.786 217.327 1.00 97.12  ? 279 ALA A CA  1 
ATOM   1672 C C   . ALA A 1 279 ? 176.748 144.409 218.041 1.00 97.12  ? 279 ALA A C   1 
ATOM   1673 O O   . ALA A 1 279 ? 175.705 143.763 218.206 1.00 97.12  ? 279 ALA A O   1 
ATOM   1674 C CB  . ALA A 1 279 ? 178.987 143.317 218.337 1.00 97.12  ? 279 ALA A CB  1 
ATOM   1675 N N   . ALA A 1 280 ? 176.883 145.666 218.470 1.00 93.71  ? 280 ALA A N   1 
ATOM   1676 C CA  . ALA A 1 280 ? 175.783 146.341 219.147 1.00 93.71  ? 280 ALA A CA  1 
ATOM   1677 C C   . ALA A 1 280 ? 174.601 146.545 218.211 1.00 93.71  ? 280 ALA A C   1 
ATOM   1678 O O   . ALA A 1 280 ? 173.447 146.396 218.625 1.00 93.71  ? 280 ALA A O   1 
ATOM   1679 C CB  . ALA A 1 280 ? 176.258 147.674 219.719 1.00 93.71  ? 280 ALA A CB  1 
ATOM   1680 N N   . ALA A 1 281 ? 174.864 146.885 216.947 1.00 92.89  ? 281 ALA A N   1 
ATOM   1681 C CA  . ALA A 1 281 ? 173.775 147.031 215.986 1.00 92.89  ? 281 ALA A CA  1 
ATOM   1682 C C   . ALA A 1 281 ? 173.043 145.711 215.777 1.00 92.89  ? 281 ALA A C   1 
ATOM   1683 O O   . ALA A 1 281 ? 171.805 145.678 215.726 1.00 92.89  ? 281 ALA A O   1 
ATOM   1684 C CB  . ALA A 1 281 ? 174.315 147.564 214.660 1.00 92.89  ? 281 ALA A CB  1 
ATOM   1685 N N   . VAL A 1 282 ? 173.791 144.611 215.661 1.00 94.38  ? 282 VAL A N   1 
ATOM   1686 C CA  . VAL A 1 282 ? 173.171 143.301 215.471 1.00 94.38  ? 282 VAL A CA  1 
ATOM   1687 C C   . VAL A 1 282 ? 172.316 142.936 216.681 1.00 94.38  ? 282 VAL A C   1 
ATOM   1688 O O   . VAL A 1 282 ? 171.176 142.471 216.545 1.00 94.38  ? 282 VAL A O   1 
ATOM   1689 C CB  . VAL A 1 282 ? 174.247 142.236 215.196 1.00 94.38  ? 282 VAL A CB  1 
ATOM   1690 C CG1 . VAL A 1 282 ? 173.702 140.844 215.459 1.00 94.38  ? 282 VAL A CG1 1 
ATOM   1691 C CG2 . VAL A 1 282 ? 174.752 142.355 213.768 1.00 94.38  ? 282 VAL A CG2 1 
ATOM   1692 N N   . ALA A 1 283 ? 172.855 143.150 217.884 1.00 91.28  ? 283 ALA A N   1 
ATOM   1693 C CA  . ALA A 1 283 ? 172.097 142.847 219.094 1.00 91.28  ? 283 ALA A CA  1 
ATOM   1694 C C   . ALA A 1 283 ? 170.846 143.709 219.191 1.00 91.28  ? 283 ALA A C   1 
ATOM   1695 O O   . ALA A 1 283 ? 169.788 143.231 219.614 1.00 91.28  ? 283 ALA A O   1 
ATOM   1696 C CB  . ALA A 1 283 ? 172.977 143.036 220.328 1.00 91.28  ? 283 ALA A CB  1 
ATOM   1697 N N   . PHE A 1 284 ? 170.948 144.984 218.809 1.00 89.74  ? 284 PHE A N   1 
ATOM   1698 C CA  . PHE A 1 284 ? 169.786 145.866 218.829 1.00 89.74  ? 284 PHE A CA  1 
ATOM   1699 C C   . PHE A 1 284 ? 168.708 145.380 217.869 1.00 89.74  ? 284 PHE A C   1 
ATOM   1700 O O   . PHE A 1 284 ? 167.521 145.354 218.218 1.00 89.74  ? 284 PHE A O   1 
ATOM   1701 C CB  . PHE A 1 284 ? 170.218 147.292 218.483 1.00 89.74  ? 284 PHE A CB  1 
ATOM   1702 C CG  . PHE A 1 284 ? 169.077 148.248 218.285 1.00 89.74  ? 284 PHE A CG  1 
ATOM   1703 C CD1 . PHE A 1 284 ? 168.314 148.670 219.359 1.00 89.74  ? 284 PHE A CD1 1 
ATOM   1704 C CD2 . PHE A 1 284 ? 168.775 148.734 217.024 1.00 89.74  ? 284 PHE A CD2 1 
ATOM   1705 C CE1 . PHE A 1 284 ? 167.268 149.554 219.179 1.00 89.74  ? 284 PHE A CE1 1 
ATOM   1706 C CE2 . PHE A 1 284 ? 167.730 149.616 216.839 1.00 89.74  ? 284 PHE A CE2 1 
ATOM   1707 C CZ  . PHE A 1 284 ? 166.976 150.026 217.918 1.00 89.74  ? 284 PHE A CZ  1 
ATOM   1708 N N   . VAL A 1 285 ? 169.103 144.983 216.658 1.00 91.16  ? 285 VAL A N   1 
ATOM   1709 C CA  . VAL A 1 285 ? 168.131 144.479 215.690 1.00 91.16  ? 285 VAL A CA  1 
ATOM   1710 C C   . VAL A 1 285 ? 167.468 143.212 216.214 1.00 91.16  ? 285 VAL A C   1 
ATOM   1711 O O   . VAL A 1 285 ? 166.258 143.014 216.052 1.00 91.16  ? 285 VAL A O   1 
ATOM   1712 C CB  . VAL A 1 285 ? 168.802 144.245 214.324 1.00 91.16  ? 285 VAL A CB  1 
ATOM   1713 C CG1 . VAL A 1 285 ? 167.840 143.552 213.375 1.00 91.16  ? 285 VAL A CG1 1 
ATOM   1714 C CG2 . VAL A 1 285 ? 169.272 145.561 213.734 1.00 91.16  ? 285 VAL A CG2 1 
ATOM   1715 N N   . ILE A 1 286 ? 168.248 142.334 216.848 1.00 93.23  ? 286 ILE A N   1 
ATOM   1716 C CA  . ILE A 1 286 ? 167.684 141.104 217.402 1.00 93.23  ? 286 ILE A CA  1 
ATOM   1717 C C   . ILE A 1 286 ? 166.692 141.421 218.517 1.00 93.23  ? 286 ILE A C   1 
ATOM   1718 O O   . ILE A 1 286 ? 165.614 140.820 218.599 1.00 93.23  ? 286 ILE A O   1 
ATOM   1719 C CB  . ILE A 1 286 ? 168.811 140.174 217.889 1.00 93.23  ? 286 ILE A CB  1 
ATOM   1720 C CG1 . ILE A 1 286 ? 169.520 139.531 216.698 1.00 93.23  ? 286 ILE A CG1 1 
ATOM   1721 C CG2 . ILE A 1 286 ? 168.264 139.099 218.809 1.00 93.23  ? 286 ILE A CG2 1 
ATOM   1722 C CD1 . ILE A 1 286 ? 170.593 138.547 217.093 1.00 93.23  ? 286 ILE A CD1 1 
ATOM   1723 N N   . VAL A 1 287 ? 167.036 142.370 219.389 1.00 91.76  ? 287 VAL A N   1 
ATOM   1724 C CA  . VAL A 1 287 ? 166.175 142.693 220.524 1.00 91.76  ? 287 VAL A CA  1 
ATOM   1725 C C   . VAL A 1 287 ? 164.882 143.352 220.056 1.00 91.76  ? 287 VAL A C   1 
ATOM   1726 O O   . VAL A 1 287 ? 163.808 143.107 220.620 1.00 91.76  ? 287 VAL A O   1 
ATOM   1727 C CB  . VAL A 1 287 ? 166.935 143.576 221.531 1.00 91.76  ? 287 VAL A CB  1 
ATOM   1728 C CG1 . VAL A 1 287 ? 165.975 144.215 222.522 1.00 91.76  ? 287 VAL A CG1 1 
ATOM   1729 C CG2 . VAL A 1 287 ? 167.982 142.756 222.264 1.00 91.76  ? 287 VAL A CG2 1 
ATOM   1730 N N   . GLU A 1 288 ? 164.953 144.182 219.012 1.00 92.32  ? 288 GLU A N   1 
ATOM   1731 C CA  . GLU A 1 288 ? 163.780 144.939 218.583 1.00 92.32  ? 288 GLU A CA  1 
ATOM   1732 C C   . GLU A 1 288 ? 162.668 144.064 218.019 1.00 92.32  ? 288 GLU A C   1 
ATOM   1733 O O   . GLU A 1 288 ? 161.562 144.572 217.804 1.00 92.32  ? 288 GLU A O   1 
ATOM   1734 C CB  . GLU A 1 288 ? 164.172 145.984 217.537 1.00 92.32  ? 288 GLU A CB  1 
ATOM   1735 C CG  . GLU A 1 288 ? 164.987 147.139 218.084 1.00 92.32  ? 288 GLU A CG  1 
ATOM   1736 C CD  . GLU A 1 288 ? 164.272 147.903 219.175 1.00 92.32  ? 288 GLU A CD  1 
ATOM   1737 O OE1 . GLU A 1 288 ? 163.446 148.775 218.843 1.00 92.32  ? 288 GLU A OE1 1 
ATOM   1738 O OE2 . GLU A 1 288 ? 164.539 147.637 220.365 1.00 92.32  ? 288 GLU A OE2 1 
ATOM   1739 N N   . ARG A 1 289 ? 162.929 142.780 217.765 1.00 96.00  ? 289 ARG A N   1 
ATOM   1740 C CA  . ARG A 1 289 ? 161.909 141.917 217.176 1.00 96.00  ? 289 ARG A CA  1 
ATOM   1741 C C   . ARG A 1 289 ? 160.687 141.793 218.080 1.00 96.00  ? 289 ARG A C   1 
ATOM   1742 O O   . ARG A 1 289 ? 159.548 141.803 217.600 1.00 96.00  ? 289 ARG A O   1 
ATOM   1743 C CB  . ARG A 1 289 ? 162.498 140.538 216.882 1.00 96.00  ? 289 ARG A CB  1 
ATOM   1744 C CG  . ARG A 1 289 ? 162.945 140.352 215.444 1.00 96.00  ? 289 ARG A CG  1 
ATOM   1745 C CD  . ARG A 1 289 ? 164.062 139.331 215.346 1.00 96.00  ? 289 ARG A CD  1 
ATOM   1746 N NE  . ARG A 1 289 ? 164.674 139.317 214.023 1.00 96.00  ? 289 ARG A NE  1 
ATOM   1747 C CZ  . ARG A 1 289 ? 165.667 138.515 213.666 1.00 96.00  ? 289 ARG A CZ  1 
ATOM   1748 N NH1 . ARG A 1 289 ? 166.188 137.642 214.513 1.00 96.00  ? 289 ARG A NH1 1 
ATOM   1749 N NH2 . ARG A 1 289 ? 166.150 138.590 212.429 1.00 96.00  ? 289 ARG A NH2 1 
ATOM   1750 N N   . THR A 1 290 ? 160.901 141.671 219.388 1.00 96.91  ? 290 THR A N   1 
ATOM   1751 C CA  . THR A 1 290 ? 159.821 141.456 220.344 1.00 96.91  ? 290 THR A CA  1 
ATOM   1752 C C   . THR A 1 290 ? 159.871 142.484 221.465 1.00 96.91  ? 290 THR A C   1 
ATOM   1753 O O   . THR A 1 290 ? 159.781 142.146 222.649 1.00 96.91  ? 290 THR A O   1 
ATOM   1754 C CB  . THR A 1 290 ? 159.872 140.042 220.915 1.00 96.91  ? 290 THR A CB  1 
ATOM   1755 O OG1 . THR A 1 290 ? 161.172 139.796 221.466 1.00 96.91  ? 290 THR A OG1 1 
ATOM   1756 C CG2 . THR A 1 290 ? 159.580 139.017 219.830 1.00 96.91  ? 290 THR A CG2 1 
ATOM   1757 N N   . ALA A 1 291 ? 160.017 143.758 221.112 1.00 94.46  ? 291 ALA A N   1 
ATOM   1758 C CA  . ALA A 1 291 ? 159.999 144.837 222.088 1.00 94.46  ? 291 ALA A CA  1 
ATOM   1759 C C   . ALA A 1 291 ? 158.586 145.384 222.238 1.00 94.46  ? 291 ALA A C   1 
ATOM   1760 O O   . ALA A 1 291 ? 157.817 145.425 221.274 1.00 94.46  ? 291 ALA A O   1 
ATOM   1761 C CB  . ALA A 1 291 ? 160.955 145.957 221.677 1.00 94.46  ? 291 ALA A CB  1 
ATOM   1762 N N   . GLU A 1 292 ? 158.244 145.794 223.462 1.00 95.99  ? 292 GLU A N   1 
ATOM   1763 C CA  . GLU A 1 292 ? 156.905 146.317 223.717 1.00 95.99  ? 292 GLU A CA  1 
ATOM   1764 C C   . GLU A 1 292 ? 156.683 147.646 223.004 1.00 95.99  ? 292 GLU A C   1 
ATOM   1765 O O   . GLU A 1 292 ? 155.675 147.827 222.311 1.00 95.99  ? 292 GLU A O   1 
ATOM   1766 C CB  . GLU A 1 292 ? 156.680 146.468 225.221 1.00 95.99  ? 292 GLU A CB  1 
ATOM   1767 C CG  . GLU A 1 292 ? 155.345 147.091 225.593 1.00 95.99  ? 292 GLU A CG  1 
ATOM   1768 C CD  . GLU A 1 292 ? 154.167 146.203 225.243 1.00 95.99  ? 292 GLU A CD  1 
ATOM   1769 O OE1 . GLU A 1 292 ? 154.350 144.971 225.152 1.00 95.99  ? 292 GLU A OE1 1 
ATOM   1770 O OE2 . GLU A 1 292 ? 153.054 146.739 225.060 1.00 95.99  ? 292 GLU A OE2 1 
ATOM   1771 N N   . ASN A 1 293 ? 157.612 148.588 223.162 1.00 91.34  ? 293 ASN A N   1 
ATOM   1772 C CA  . ASN A 1 293 ? 157.584 149.868 222.455 1.00 91.34  ? 293 ASN A CA  1 
ATOM   1773 C C   . ASN A 1 293 ? 158.949 150.064 221.815 1.00 91.34  ? 293 ASN A C   1 
ATOM   1774 O O   . ASN A 1 293 ? 159.868 150.610 222.441 1.00 91.34  ? 293 ASN A O   1 
ATOM   1775 C CB  . ASN A 1 293 ? 157.230 151.022 223.390 1.00 91.34  ? 293 ASN A CB  1 
ATOM   1776 C CG  . ASN A 1 293 ? 155.836 150.897 223.966 1.00 91.34  ? 293 ASN A CG  1 
ATOM   1777 O OD1 . ASN A 1 293 ? 155.661 150.726 225.171 1.00 91.34  ? 293 ASN A OD1 1 
ATOM   1778 N ND2 . ASN A 1 293 ? 154.832 150.981 223.103 1.00 91.34  ? 293 ASN A ND2 1 
ATOM   1779 N N   . PRO A 1 294 ? 159.122 149.622 220.571 1.00 86.18  ? 294 PRO A N   1 
ATOM   1780 C CA  . PRO A 1 294 ? 160.456 149.630 219.963 1.00 86.18  ? 294 PRO A CA  1 
ATOM   1781 C C   . PRO A 1 294 ? 161.006 151.041 219.818 1.00 86.18  ? 294 PRO A C   1 
ATOM   1782 O O   . PRO A 1 294 ? 160.270 151.994 219.561 1.00 86.18  ? 294 PRO A O   1 
ATOM   1783 C CB  . PRO A 1 294 ? 160.230 148.974 218.595 1.00 86.18  ? 294 PRO A CB  1 
ATOM   1784 C CG  . PRO A 1 294 ? 158.875 148.357 218.657 1.00 86.18  ? 294 PRO A CG  1 
ATOM   1785 C CD  . PRO A 1 294 ? 158.090 149.162 219.632 1.00 86.18  ? 294 PRO A CD  1 
ATOM   1786 N N   . VAL A 1 295 ? 162.322 151.164 219.998 1.00 82.22  ? 295 VAL A N   1 
ATOM   1787 C CA  . VAL A 1 295 ? 162.989 152.433 219.735 1.00 82.22  ? 295 VAL A CA  1 
ATOM   1788 C C   . VAL A 1 295 ? 162.989 152.728 218.241 1.00 82.22  ? 295 VAL A C   1 
ATOM   1789 O O   . VAL A 1 295 ? 162.844 153.882 217.822 1.00 82.22  ? 295 VAL A O   1 
ATOM   1790 C CB  . VAL A 1 295 ? 164.413 152.416 220.318 1.00 82.22  ? 295 VAL A CB  1 
ATOM   1791 C CG1 . VAL A 1 295 ? 165.154 153.690 219.962 1.00 82.22  ? 295 VAL A CG1 1 
ATOM   1792 C CG2 . VAL A 1 295 ? 164.361 152.237 221.824 1.00 82.22  ? 295 VAL A CG2 1 
ATOM   1793 N N   . VAL A 1 296 ? 163.156 151.698 217.417 1.00 80.56  ? 296 VAL A N   1 
ATOM   1794 C CA  . VAL A 1 296 ? 163.096 151.839 215.964 1.00 80.56  ? 296 VAL A CA  1 
ATOM   1795 C C   . VAL A 1 296 ? 162.070 150.860 215.408 1.00 80.56  ? 296 VAL A C   1 
ATOM   1796 O O   . VAL A 1 296 ? 162.325 149.648 215.382 1.00 80.56  ? 296 VAL A O   1 
ATOM   1797 C CB  . VAL A 1 296 ? 164.474 151.614 215.325 1.00 80.56  ? 296 VAL A CB  1 
ATOM   1798 C CG1 . VAL A 1 296 ? 164.365 151.635 213.811 1.00 80.56  ? 296 VAL A CG1 1 
ATOM   1799 C CG2 . VAL A 1 296 ? 165.452 152.668 215.800 1.00 80.56  ? 296 VAL A CG2 1 
ATOM   1800 N N   . PRO A 1 297 ? 160.902 151.326 214.963 1.00 82.23  ? 297 PRO A N   1 
ATOM   1801 C CA  . PRO A 1 297 ? 159.903 150.422 214.373 1.00 82.23  ? 297 PRO A CA  1 
ATOM   1802 C C   . PRO A 1 297 ? 160.289 150.038 212.954 1.00 82.23  ? 297 PRO A C   1 
ATOM   1803 O O   . PRO A 1 297 ? 160.205 150.850 212.028 1.00 82.23  ? 297 PRO A O   1 
ATOM   1804 C CB  . PRO A 1 297 ? 158.613 151.259 214.411 1.00 82.23  ? 297 PRO A CB  1 
ATOM   1805 C CG  . PRO A 1 297 ? 158.925 152.466 215.253 1.00 82.23  ? 297 PRO A CG  1 
ATOM   1806 C CD  . PRO A 1 297 ? 160.385 152.694 215.101 1.00 82.23  ? 297 PRO A CD  1 
ATOM   1807 N N   . PHE A 1 298 ? 160.713 148.786 212.778 1.00 81.46  ? 298 PHE A N   1 
ATOM   1808 C CA  . PHE A 1 298 ? 161.159 148.321 211.471 1.00 81.46  ? 298 PHE A CA  1 
ATOM   1809 C C   . PHE A 1 298 ? 160.008 148.007 210.524 1.00 81.46  ? 298 PHE A C   1 
ATOM   1810 O O   . PHE A 1 298 ? 160.227 147.935 209.311 1.00 81.46  ? 298 PHE A O   1 
ATOM   1811 C CB  . PHE A 1 298 ? 162.043 147.082 211.628 1.00 81.46  ? 298 PHE A CB  1 
ATOM   1812 C CG  . PHE A 1 298 ? 163.435 147.388 212.101 1.00 81.46  ? 298 PHE A CG  1 
ATOM   1813 C CD1 . PHE A 1 298 ? 164.373 147.917 211.234 1.00 81.46  ? 298 PHE A CD1 1 
ATOM   1814 C CD2 . PHE A 1 298 ? 163.805 147.145 213.411 1.00 81.46  ? 298 PHE A CD2 1 
ATOM   1815 C CE1 . PHE A 1 298 ? 165.652 148.199 211.666 1.00 81.46  ? 298 PHE A CE1 1 
ATOM   1816 C CE2 . PHE A 1 298 ? 165.083 147.426 213.847 1.00 81.46  ? 298 PHE A CE2 1 
ATOM   1817 C CZ  . PHE A 1 298 ? 166.006 147.954 212.974 1.00 81.46  ? 298 PHE A CZ  1 
ATOM   1818 N N   . HIS A 1 299 ? 158.794 147.817 211.043 1.00 83.35  ? 299 HIS A N   1 
ATOM   1819 C CA  . HIS A 1 299 ? 157.674 147.453 210.181 1.00 83.35  ? 299 HIS A CA  1 
ATOM   1820 C C   . HIS A 1 299 ? 157.155 148.641 209.381 1.00 83.35  ? 299 HIS A C   1 
ATOM   1821 O O   . HIS A 1 299 ? 156.569 148.452 208.310 1.00 83.35  ? 299 HIS A O   1 
ATOM   1822 C CB  . HIS A 1 299 ? 156.549 146.845 211.015 1.00 83.35  ? 299 HIS A CB  1 
ATOM   1823 C CG  . HIS A 1 299 ? 156.273 147.585 212.285 1.00 83.35  ? 299 HIS A CG  1 
ATOM   1824 N ND1 . HIS A 1 299 ? 156.951 147.328 213.456 1.00 83.35  ? 299 HIS A ND1 1 
ATOM   1825 C CD2 . HIS A 1 299 ? 155.401 148.580 212.565 1.00 83.35  ? 299 HIS A CD2 1 
ATOM   1826 C CE1 . HIS A 1 299 ? 156.504 148.130 214.406 1.00 83.35  ? 299 HIS A CE1 1 
ATOM   1827 N NE2 . HIS A 1 299 ? 155.563 148.900 213.891 1.00 83.35  ? 299 HIS A NE2 1 
ATOM   1828 N N   . LEU A 1 300 ? 157.351 149.864 209.878 1.00 79.44  ? 300 LEU A N   1 
ATOM   1829 C CA  . LEU A 1 300 ? 156.836 151.038 209.182 1.00 79.44  ? 300 LEU A CA  1 
ATOM   1830 C C   . LEU A 1 300 ? 157.508 151.257 207.835 1.00 79.44  ? 300 LEU A C   1 
ATOM   1831 O O   . LEU A 1 300 ? 156.937 151.935 206.974 1.00 79.44  ? 300 LEU A O   1 
ATOM   1832 C CB  . LEU A 1 300 ? 157.008 152.288 210.045 1.00 79.44  ? 300 LEU A CB  1 
ATOM   1833 C CG  . LEU A 1 300 ? 155.932 152.561 211.094 1.00 79.44  ? 300 LEU A CG  1 
ATOM   1834 C CD1 . LEU A 1 300 ? 156.130 153.937 211.700 1.00 79.44  ? 300 LEU A CD1 1 
ATOM   1835 C CD2 . LEU A 1 300 ? 154.549 152.435 210.486 1.00 79.44  ? 300 LEU A CD2 1 
ATOM   1836 N N   . PHE A 1 301 ? 158.699 150.699 207.630 1.00 76.31  ? 301 PHE A N   1 
ATOM   1837 C CA  . PHE A 1 301 ? 159.464 150.906 206.410 1.00 76.31  ? 301 PHE A CA  1 
ATOM   1838 C C   . PHE A 1 301 ? 159.212 149.826 205.365 1.00 76.31  ? 301 PHE A C   1 
ATOM   1839 O O   . PHE A 1 301 ? 160.010 149.677 204.434 1.00 76.31  ? 301 PHE A O   1 
ATOM   1840 C CB  . PHE A 1 301 ? 160.953 150.999 206.740 1.00 76.31  ? 301 PHE A CB  1 
ATOM   1841 C CG  . PHE A 1 301 ? 161.313 152.218 207.537 1.00 76.31  ? 301 PHE A CG  1 
ATOM   1842 C CD1 . PHE A 1 301 ? 161.150 152.236 208.912 1.00 76.31  ? 301 PHE A CD1 1 
ATOM   1843 C CD2 . PHE A 1 301 ? 161.801 153.349 206.911 1.00 76.31  ? 301 PHE A CD2 1 
ATOM   1844 C CE1 . PHE A 1 301 ? 161.470 153.359 209.645 1.00 76.31  ? 301 PHE A CE1 1 
ATOM   1845 C CE2 . PHE A 1 301 ? 162.125 154.472 207.640 1.00 76.31  ? 301 PHE A CE2 1 
ATOM   1846 C CZ  . PHE A 1 301 ? 161.958 154.477 209.009 1.00 76.31  ? 301 PHE A CZ  1 
ATOM   1847 N N   . ARG A 1 302 ? 158.123 149.073 205.500 1.00 84.51  ? 302 ARG A N   1 
ATOM   1848 C CA  . ARG A 1 302 ? 157.712 148.106 204.492 1.00 84.51  ? 302 ARG A CA  1 
ATOM   1849 C C   . ARG A 1 302 ? 156.927 148.746 203.355 1.00 84.51  ? 302 ARG A C   1 
ATOM   1850 O O   . ARG A 1 302 ? 156.271 148.028 202.592 1.00 84.51  ? 302 ARG A O   1 
ATOM   1851 C CB  . ARG A 1 302 ? 156.880 146.996 205.137 1.00 84.51  ? 302 ARG A CB  1 
ATOM   1852 C CG  . ARG A 1 302 ? 157.653 146.141 206.123 1.00 84.51  ? 302 ARG A CG  1 
ATOM   1853 C CD  . ARG A 1 302 ? 157.070 144.740 206.227 1.00 84.51  ? 302 ARG A CD  1 
ATOM   1854 N NE  . ARG A 1 302 ? 157.444 144.085 207.475 1.00 84.51  ? 302 ARG A NE  1 
ATOM   1855 C CZ  . ARG A 1 302 ? 158.653 143.609 207.743 1.00 84.51  ? 302 ARG A CZ  1 
ATOM   1856 N NH1 . ARG A 1 302 ? 159.637 143.684 206.862 1.00 84.51  ? 302 ARG A NH1 1 
ATOM   1857 N NH2 . ARG A 1 302 ? 158.880 143.043 208.925 1.00 84.51  ? 302 ARG A NH2 1 
ATOM   1858 N N   . ASP A 1 303 ? 156.971 150.070 203.234 1.00 79.82  ? 303 ASP A N   1 
ATOM   1859 C CA  . ASP A 1 303 ? 156.297 150.799 202.171 1.00 79.82  ? 303 ASP A CA  1 
ATOM   1860 C C   . ASP A 1 303 ? 157.330 151.405 201.235 1.00 79.82  ? 303 ASP A C   1 
ATOM   1861 O O   . ASP A 1 303 ? 158.366 151.906 201.681 1.00 79.82  ? 303 ASP A O   1 
ATOM   1862 C CB  . ASP A 1 303 ? 155.404 151.904 202.738 1.00 79.82  ? 303 ASP A CB  1 
ATOM   1863 C CG  . ASP A 1 303 ? 154.216 151.360 203.497 1.00 79.82  ? 303 ASP A CG  1 
ATOM   1864 O OD1 . ASP A 1 303 ? 153.830 150.199 203.246 1.00 79.82  ? 303 ASP A OD1 1 
ATOM   1865 O OD2 . ASP A 1 303 ? 153.663 152.095 204.340 1.00 79.82  ? 303 ASP A OD2 1 
ATOM   1866 N N   . ARG A 1 304 ? 157.045 151.355 199.933 1.00 76.30  ? 304 ARG A N   1 
ATOM   1867 C CA  . ARG A 1 304 ? 157.961 151.932 198.956 1.00 76.30  ? 304 ARG A CA  1 
ATOM   1868 C C   . ARG A 1 304 ? 158.096 153.438 199.148 1.00 76.30  ? 304 ARG A C   1 
ATOM   1869 O O   . ARG A 1 304 ? 159.201 153.988 199.051 1.00 76.30  ? 304 ARG A O   1 
ATOM   1870 C CB  . ARG A 1 304 ? 157.484 151.603 197.540 1.00 76.30  ? 304 ARG A CB  1 
ATOM   1871 C CG  . ARG A 1 304 ? 158.133 152.433 196.444 1.00 76.30  ? 304 ARG A CG  1 
ATOM   1872 C CD  . ARG A 1 304 ? 157.429 152.236 195.110 1.00 76.30  ? 304 ARG A CD  1 
ATOM   1873 N NE  . ARG A 1 304 ? 157.208 153.498 194.413 1.00 76.30  ? 304 ARG A NE  1 
ATOM   1874 C CZ  . ARG A 1 304 ? 156.464 153.632 193.324 1.00 76.30  ? 304 ARG A CZ  1 
ATOM   1875 N NH1 . ARG A 1 304 ? 155.854 152.596 192.772 1.00 76.30  ? 304 ARG A NH1 1 
ATOM   1876 N NH2 . ARG A 1 304 ? 156.329 154.834 192.773 1.00 76.30  ? 304 ARG A NH2 1 
ATOM   1877 N N   . ASN A 1 305 ? 156.982 154.117 199.433 1.00 72.73  ? 305 ASN A N   1 
ATOM   1878 C CA  . ASN A 1 305 ? 157.002 155.570 199.562 1.00 72.73  ? 305 ASN A CA  1 
ATOM   1879 C C   . ASN A 1 305 ? 157.944 156.016 200.673 1.00 72.73  ? 305 ASN A C   1 
ATOM   1880 O O   . ASN A 1 305 ? 158.801 156.881 200.462 1.00 72.73  ? 305 ASN A O   1 
ATOM   1881 C CB  . ASN A 1 305 ? 155.589 156.092 199.823 1.00 72.73  ? 305 ASN A CB  1 
ATOM   1882 C CG  . ASN A 1 305 ? 154.588 155.610 198.795 1.00 72.73  ? 305 ASN A CG  1 
ATOM   1883 O OD1 . ASN A 1 305 ? 153.544 155.061 199.142 1.00 72.73  ? 305 ASN A OD1 1 
ATOM   1884 N ND2 . ASN A 1 305 ? 154.898 155.818 197.523 1.00 72.73  ? 305 ASN A ND2 1 
ATOM   1885 N N   . ARG A 1 306 ? 157.802 155.432 201.865 1.00 70.92  ? 306 ARG A N   1 
ATOM   1886 C CA  . ARG A 1 306 ? 158.625 155.847 202.997 1.00 70.92  ? 306 ARG A CA  1 
ATOM   1887 C C   . ARG A 1 306 ? 160.098 155.540 202.764 1.00 70.92  ? 306 ARG A C   1 
ATOM   1888 O O   . ARG A 1 306 ? 160.965 156.363 203.079 1.00 70.92  ? 306 ARG A O   1 
ATOM   1889 C CB  . ARG A 1 306 ? 158.137 155.173 204.277 1.00 70.92  ? 306 ARG A CB  1 
ATOM   1890 C CG  . ARG A 1 306 ? 158.699 155.789 205.544 1.00 70.92  ? 306 ARG A CG  1 
ATOM   1891 C CD  . ARG A 1 306 ? 157.971 155.286 206.775 1.00 70.92  ? 306 ARG A CD  1 
ATOM   1892 N NE  . ARG A 1 306 ? 156.788 156.084 207.072 1.00 70.92  ? 306 ARG A NE  1 
ATOM   1893 C CZ  . ARG A 1 306 ? 155.549 155.613 207.066 1.00 70.92  ? 306 ARG A CZ  1 
ATOM   1894 N NH1 . ARG A 1 306 ? 155.292 154.347 206.784 1.00 70.92  ? 306 ARG A NH1 1 
ATOM   1895 N NH2 . ARG A 1 306 ? 154.543 156.433 207.351 1.00 70.92  ? 306 ARG A NH2 1 
ATOM   1896 N N   . LEU A 1 307 ? 160.402 154.361 202.220 1.00 68.03  ? 307 LEU A N   1 
ATOM   1897 C CA  . LEU A 1 307 ? 161.794 153.987 201.992 1.00 68.03  ? 307 LEU A CA  1 
ATOM   1898 C C   . LEU A 1 307 ? 162.457 154.907 200.972 1.00 68.03  ? 307 LEU A C   1 
ATOM   1899 O O   . LEU A 1 307 ? 163.583 155.383 201.186 1.00 68.03  ? 307 LEU A O   1 
ATOM   1900 C CB  . LEU A 1 307 ? 161.864 152.531 201.536 1.00 68.03  ? 307 LEU A CB  1 
ATOM   1901 C CG  . LEU A 1 307 ? 163.225 151.843 201.548 1.00 68.03  ? 307 LEU A CG  1 
ATOM   1902 C CD1 . LEU A 1 307 ? 163.748 151.737 202.967 1.00 68.03  ? 307 LEU A CD1 1 
ATOM   1903 C CD2 . LEU A 1 307 ? 163.121 150.470 200.912 1.00 68.03  ? 307 LEU A CD2 1 
ATOM   1904 N N   . VAL A 1 308 ? 161.766 155.183 199.862 1.00 66.82  ? 308 VAL A N   1 
ATOM   1905 C CA  . VAL A 1 308 ? 162.317 156.086 198.856 1.00 66.82  ? 308 VAL A CA  1 
ATOM   1906 C C   . VAL A 1 308 ? 162.469 157.489 199.427 1.00 66.82  ? 308 VAL A C   1 
ATOM   1907 O O   . VAL A 1 308 ? 163.469 158.174 199.176 1.00 66.82  ? 308 VAL A O   1 
ATOM   1908 C CB  . VAL A 1 308 ? 161.440 156.076 197.590 1.00 66.82  ? 308 VAL A CB  1 
ATOM   1909 C CG1 . VAL A 1 308 ? 161.885 157.159 196.628 1.00 66.82  ? 308 VAL A CG1 1 
ATOM   1910 C CG2 . VAL A 1 308 ? 161.505 154.718 196.920 1.00 66.82  ? 308 VAL A CG2 1 
ATOM   1911 N N   . THR A 1 309 ? 161.487 157.936 200.216 1.00 65.20  ? 309 THR A N   1 
ATOM   1912 C CA  . THR A 1 309 ? 161.562 159.263 200.814 1.00 65.20  ? 309 THR A CA  1 
ATOM   1913 C C   . THR A 1 309 ? 162.759 159.382 201.745 1.00 65.20  ? 309 THR A C   1 
ATOM   1914 O O   . THR A 1 309 ? 163.452 160.403 201.747 1.00 65.20  ? 309 THR A O   1 
ATOM   1915 C CB  . THR A 1 309 ? 160.270 159.570 201.569 1.00 65.20  ? 309 THR A CB  1 
ATOM   1916 O OG1 . THR A 1 309 ? 159.154 159.424 200.684 1.00 65.20  ? 309 THR A OG1 1 
ATOM   1917 C CG2 . THR A 1 309 ? 160.293 160.986 202.106 1.00 65.20  ? 309 THR A CG2 1 
ATOM   1918 N N   . PHE A 1 310 ? 163.025 158.345 202.539 1.00 62.71  ? 310 PHE A N   1 
ATOM   1919 C CA  . PHE A 1 310 ? 164.135 158.420 203.484 1.00 62.71  ? 310 PHE A CA  1 
ATOM   1920 C C   . PHE A 1 310 ? 165.481 158.353 202.771 1.00 62.71  ? 310 PHE A C   1 
ATOM   1921 O O   . PHE A 1 310 ? 166.433 159.041 203.165 1.00 62.71  ? 310 PHE A O   1 
ATOM   1922 C CB  . PHE A 1 310 ? 164.000 157.319 204.532 1.00 62.71  ? 310 PHE A CB  1 
ATOM   1923 C CG  . PHE A 1 310 ? 163.133 157.708 205.694 1.00 62.71  ? 310 PHE A CG  1 
ATOM   1924 C CD1 . PHE A 1 310 ? 161.904 158.303 205.484 1.00 62.71  ? 310 PHE A CD1 1 
ATOM   1925 C CD2 . PHE A 1 310 ? 163.551 157.499 206.992 1.00 62.71  ? 310 PHE A CD2 1 
ATOM   1926 C CE1 . PHE A 1 310 ? 161.107 158.672 206.543 1.00 62.71  ? 310 PHE A CE1 1 
ATOM   1927 C CE2 . PHE A 1 310 ? 162.754 157.867 208.054 1.00 62.71  ? 310 PHE A CE2 1 
ATOM   1928 C CZ  . PHE A 1 310 ? 161.533 158.453 207.828 1.00 62.71  ? 310 PHE A CZ  1 
ATOM   1929 N N   . SER A 1 311 ? 165.581 157.549 201.708 1.00 63.49  ? 311 SER A N   1 
ATOM   1930 C CA  . SER A 1 311 ? 166.804 157.563 200.908 1.00 63.49  ? 311 SER A CA  1 
ATOM   1931 C C   . SER A 1 311 ? 167.043 158.940 200.293 1.00 63.49  ? 311 SER A C   1 
ATOM   1932 O O   . SER A 1 311 ? 168.176 159.451 200.291 1.00 63.49  ? 311 SER A O   1 
ATOM   1933 C CB  . SER A 1 311 ? 166.725 156.495 199.819 1.00 63.49  ? 311 SER A CB  1 
ATOM   1934 O OG  . SER A 1 311 ? 166.631 155.199 200.382 1.00 63.49  ? 311 SER A OG  1 
ATOM   1935 N N   . ALA A 1 312 ? 165.980 159.556 199.766 1.00 62.86  ? 312 ALA A N   1 
ATOM   1936 C CA  . ALA A 1 312 ? 166.100 160.894 199.200 1.00 62.86  ? 312 ALA A CA  1 
ATOM   1937 C C   . ALA A 1 312 ? 166.502 161.904 200.262 1.00 62.86  ? 312 ALA A C   1 
ATOM   1938 O O   . ALA A 1 312 ? 167.292 162.812 199.993 1.00 62.86  ? 312 ALA A O   1 
ATOM   1939 C CB  . ALA A 1 312 ? 164.788 161.304 198.535 1.00 62.86  ? 312 ALA A CB  1 
ATOM   1940 N N   . ILE A 1 313 ? 165.962 161.766 201.474 1.00 62.08  ? 313 ILE A N   1 
ATOM   1941 C CA  . ILE A 1 313 ? 166.324 162.667 202.565 1.00 62.08  ? 313 ILE A CA  1 
ATOM   1942 C C   . ILE A 1 313 ? 167.810 162.551 202.872 1.00 62.08  ? 313 ILE A C   1 
ATOM   1943 O O   . ILE A 1 313 ? 168.512 163.558 203.029 1.00 62.08  ? 313 ILE A O   1 
ATOM   1944 C CB  . ILE A 1 313 ? 165.469 162.369 203.809 1.00 62.08  ? 313 ILE A CB  1 
ATOM   1945 C CG1 . ILE A 1 313 ? 164.085 162.999 203.672 1.00 62.08  ? 313 ILE A CG1 1 
ATOM   1946 C CG2 . ILE A 1 313 ? 166.155 162.871 205.065 1.00 62.08  ? 313 ILE A CG2 1 
ATOM   1947 C CD1 . ILE A 1 313 ? 163.125 162.568 204.746 1.00 62.08  ? 313 ILE A CD1 1 
ATOM   1948 N N   . LEU A 1 314 ? 168.314 161.317 202.950 1.00 61.29  ? 314 LEU A N   1 
ATOM   1949 C CA  . LEU A 1 314 ? 169.732 161.110 203.231 1.00 61.29  ? 314 LEU A CA  1 
ATOM   1950 C C   . LEU A 1 314 ? 170.608 161.782 202.178 1.00 61.29  ? 314 LEU A C   1 
ATOM   1951 O O   . LEU A 1 314 ? 171.499 162.583 202.505 1.00 61.29  ? 314 LEU A O   1 
ATOM   1952 C CB  . LEU A 1 314 ? 170.031 159.611 203.305 1.00 61.29  ? 314 LEU A CB  1 
ATOM   1953 C CG  . LEU A 1 314 ? 171.439 159.163 203.701 1.00 61.29  ? 314 LEU A CG  1 
ATOM   1954 C CD1 . LEU A 1 314 ? 171.367 157.966 204.626 1.00 61.29  ? 314 LEU A CD1 1 
ATOM   1955 C CD2 . LEU A 1 314 ? 172.264 158.825 202.477 1.00 61.29  ? 314 LEU A CD2 1 
ATOM   1956 N N   . LEU A 1 315 ? 170.353 161.489 200.900 1.00 63.54  ? 315 LEU A N   1 
ATOM   1957 C CA  . LEU A 1 315 ? 171.224 162.045 199.868 1.00 63.54  ? 315 LEU A CA  1 
ATOM   1958 C C   . LEU A 1 315 ? 171.051 163.553 199.711 1.00 63.54  ? 315 LEU A C   1 
ATOM   1959 O O   . LEU A 1 315 ? 172.024 164.253 199.408 1.00 63.54  ? 315 LEU A O   1 
ATOM   1960 C CB  . LEU A 1 315 ? 171.010 161.330 198.536 1.00 63.54  ? 315 LEU A CB  1 
ATOM   1961 C CG  . LEU A 1 315 ? 171.429 159.859 198.511 1.00 63.54  ? 315 LEU A CG  1 
ATOM   1962 C CD1 . LEU A 1 315 ? 171.052 159.212 197.195 1.00 63.54  ? 315 LEU A CD1 1 
ATOM   1963 C CD2 . LEU A 1 315 ? 172.922 159.731 198.757 1.00 63.54  ? 315 LEU A CD2 1 
ATOM   1964 N N   . ALA A 1 316 ? 169.841 164.080 199.921 1.00 61.46  ? 316 ALA A N   1 
ATOM   1965 C CA  . ALA A 1 316 ? 169.639 165.522 199.844 1.00 61.46  ? 316 ALA A CA  1 
ATOM   1966 C C   . ALA A 1 316 ? 170.368 166.244 200.969 1.00 61.46  ? 316 ALA A C   1 
ATOM   1967 O O   . ALA A 1 316 ? 170.963 167.306 200.747 1.00 61.46  ? 316 ALA A O   1 
ATOM   1968 C CB  . ALA A 1 316 ? 168.147 165.843 199.876 1.00 61.46  ? 316 ALA A CB  1 
ATOM   1969 N N   . GLY A 1 317 ? 170.328 165.691 202.184 1.00 61.63  ? 317 GLY A N   1 
ATOM   1970 C CA  . GLY A 1 317 ? 171.108 166.268 203.264 1.00 61.63  ? 317 GLY A CA  1 
ATOM   1971 C C   . GLY A 1 317 ? 172.593 166.253 202.965 1.00 61.63  ? 317 GLY A C   1 
ATOM   1972 O O   . GLY A 1 317 ? 173.303 167.228 203.235 1.00 61.63  ? 317 GLY A O   1 
ATOM   1973 N N   . GLY A 1 318 ? 173.082 165.152 202.388 1.00 59.94  ? 318 GLY A N   1 
ATOM   1974 C CA  . GLY A 1 318 ? 174.481 165.108 201.990 1.00 59.94  ? 318 GLY A CA  1 
ATOM   1975 C C   . GLY A 1 318 ? 174.837 166.171 200.968 1.00 59.94  ? 318 GLY A C   1 
ATOM   1976 O O   . GLY A 1 318 ? 175.863 166.850 201.091 1.00 59.94  ? 318 GLY A O   1 
ATOM   1977 N N   . VAL A 1 319 ? 173.988 166.337 199.952 1.00 59.86  ? 319 VAL A N   1 
ATOM   1978 C CA  . VAL A 1 319 ? 174.240 167.333 198.913 1.00 59.86  ? 319 VAL A CA  1 
ATOM   1979 C C   . VAL A 1 319 ? 174.266 168.733 199.514 1.00 59.86  ? 319 VAL A C   1 
ATOM   1980 O O   . VAL A 1 319 ? 175.143 169.549 199.201 1.00 59.86  ? 319 VAL A O   1 
ATOM   1981 C CB  . VAL A 1 319 ? 173.186 167.219 197.797 1.00 59.86  ? 319 VAL A CB  1 
ATOM   1982 C CG1 . VAL A 1 319 ? 173.197 168.458 196.920 1.00 59.86  ? 319 VAL A CG1 1 
ATOM   1983 C CG2 . VAL A 1 319 ? 173.427 165.972 196.966 1.00 59.86  ? 319 VAL A CG2 1 
ATOM   1984 N N   . MET A 1 320 ? 173.304 169.032 200.389 1.00 61.01  ? 320 MET A N   1 
ATOM   1985 C CA  . MET A 1 320 ? 173.226 170.368 200.969 1.00 61.01  ? 320 MET A CA  1 
ATOM   1986 C C   . MET A 1 320 ? 174.434 170.660 201.853 1.00 61.01  ? 320 MET A C   1 
ATOM   1987 O O   . MET A 1 320 ? 174.996 171.763 201.806 1.00 61.01  ? 320 MET A O   1 
ATOM   1988 C CB  . MET A 1 320 ? 171.929 170.515 201.761 1.00 61.01  ? 320 MET A CB  1 
ATOM   1989 C CG  . MET A 1 320 ? 171.773 171.858 202.437 1.00 61.01  ? 320 MET A CG  1 
ATOM   1990 S SD  . MET A 1 320 ? 170.992 173.028 201.312 1.00 61.01  ? 320 MET A SD  1 
ATOM   1991 C CE  . MET A 1 320 ? 172.074 174.439 201.470 1.00 61.01  ? 320 MET A CE  1 
ATOM   1992 N N   . PHE A 1 321 ? 174.851 169.685 202.666 1.00 59.83  ? 321 PHE A N   1 
ATOM   1993 C CA  . PHE A 1 321 ? 176.023 169.879 203.514 1.00 59.83  ? 321 PHE A CA  1 
ATOM   1994 C C   . PHE A 1 321 ? 177.283 170.092 202.683 1.00 59.83  ? 321 PHE A C   1 
ATOM   1995 O O   . PHE A 1 321 ? 178.108 170.964 202.998 1.00 59.83  ? 321 PHE A O   1 
ATOM   1996 C CB  . PHE A 1 321 ? 176.190 168.681 204.446 1.00 59.83  ? 321 PHE A CB  1 
ATOM   1997 C CG  . PHE A 1 321 ? 177.116 168.929 205.601 1.00 59.83  ? 321 PHE A CG  1 
ATOM   1998 C CD1 . PHE A 1 321 ? 176.692 169.644 206.705 1.00 59.83  ? 321 PHE A CD1 1 
ATOM   1999 C CD2 . PHE A 1 321 ? 178.407 168.435 205.586 1.00 59.83  ? 321 PHE A CD2 1 
ATOM   2000 C CE1 . PHE A 1 321 ? 177.542 169.867 207.767 1.00 59.83  ? 321 PHE A CE1 1 
ATOM   2001 C CE2 . PHE A 1 321 ? 179.258 168.654 206.647 1.00 59.83  ? 321 PHE A CE2 1 
ATOM   2002 C CZ  . PHE A 1 321 ? 178.825 169.371 207.737 1.00 59.83  ? 321 PHE A CZ  1 
ATOM   2003 N N   . SER A 1 322 ? 177.455 169.298 201.621 1.00 58.78  ? 322 SER A N   1 
ATOM   2004 C CA  . SER A 1 322 ? 178.614 169.476 200.755 1.00 58.78  ? 322 SER A CA  1 
ATOM   2005 C C   . SER A 1 322 ? 178.613 170.857 200.115 1.00 58.78  ? 322 SER A C   1 
ATOM   2006 O O   . SER A 1 322 ? 179.652 171.526 200.069 1.00 58.78  ? 322 SER A O   1 
ATOM   2007 C CB  . SER A 1 322 ? 178.639 168.390 199.683 1.00 58.78  ? 322 SER A CB  1 
ATOM   2008 O OG  . SER A 1 322 ? 178.551 167.105 200.267 1.00 58.78  ? 322 SER A OG  1 
ATOM   2009 N N   . LEU A 1 323 ? 177.454 171.302 199.620 1.00 57.66  ? 323 LEU A N   1 
ATOM   2010 C CA  . LEU A 1 323 ? 177.359 172.644 199.053 1.00 57.66  ? 323 LEU A CA  1 
ATOM   2011 C C   . LEU A 1 323 ? 177.770 173.698 200.069 1.00 57.66  ? 323 LEU A C   1 
ATOM   2012 O O   . LEU A 1 323 ? 178.577 174.581 199.767 1.00 57.66  ? 323 LEU A O   1 
ATOM   2013 C CB  . LEU A 1 323 ? 175.938 172.918 198.561 1.00 57.66  ? 323 LEU A CB  1 
ATOM   2014 C CG  . LEU A 1 323 ? 175.523 172.399 197.189 1.00 57.66  ? 323 LEU A CG  1 
ATOM   2015 C CD1 . LEU A 1 323 ? 174.038 172.611 196.982 1.00 57.66  ? 323 LEU A CD1 1 
ATOM   2016 C CD2 . LEU A 1 323 ? 176.313 173.110 196.114 1.00 57.66  ? 323 LEU A CD2 1 
ATOM   2017 N N   . THR A 1 324 ? 177.224 173.620 201.283 1.00 58.80  ? 324 THR A N   1 
ATOM   2018 C CA  . THR A 1 324 ? 177.520 174.635 202.289 1.00 58.80  ? 324 THR A CA  1 
ATOM   2019 C C   . THR A 1 324 ? 179.014 174.698 202.587 1.00 58.80  ? 324 THR A C   1 
ATOM   2020 O O   . THR A 1 324 ? 179.627 175.776 202.541 1.00 58.80  ? 324 THR A O   1 
ATOM   2021 C CB  . THR A 1 324 ? 176.730 174.351 203.565 1.00 58.80  ? 324 THR A CB  1 
ATOM   2022 O OG1 . THR A 1 324 ? 175.327 174.415 203.281 1.00 58.80  ? 324 THR A OG1 1 
ATOM   2023 C CG2 . THR A 1 324 ? 177.070 175.365 204.638 1.00 58.80  ? 324 THR A CG2 1 
ATOM   2024 N N   . VAL A 1 325 ? 179.624 173.544 202.871 1.00 58.26  ? 325 VAL A N   1 
ATOM   2025 C CA  . VAL A 1 325 ? 181.033 173.537 203.257 1.00 58.26  ? 325 VAL A CA  1 
ATOM   2026 C C   . VAL A 1 325 ? 181.916 173.998 202.102 1.00 58.26  ? 325 VAL A C   1 
ATOM   2027 O O   . VAL A 1 325 ? 182.834 174.807 202.291 1.00 58.26  ? 325 VAL A O   1 
ATOM   2028 C CB  . VAL A 1 325 ? 181.441 172.146 203.772 1.00 58.26  ? 325 VAL A CB  1 
ATOM   2029 C CG1 . VAL A 1 325 ? 182.940 172.082 203.992 1.00 58.26  ? 325 VAL A CG1 1 
ATOM   2030 C CG2 . VAL A 1 325 ? 180.706 171.834 205.059 1.00 58.26  ? 325 VAL A CG2 1 
ATOM   2031 N N   . CYS A 1 326 ? 181.658 173.498 200.889 1.00 61.27  ? 326 CYS A N   1 
ATOM   2032 C CA  . CYS A 1 326 ? 182.493 173.867 199.751 1.00 61.27  ? 326 CYS A CA  1 
ATOM   2033 C C   . CYS A 1 326 ? 182.361 175.347 199.411 1.00 61.27  ? 326 CYS A C   1 
ATOM   2034 O O   . CYS A 1 326 ? 183.366 176.010 199.130 1.00 61.27  ? 326 CYS A O   1 
ATOM   2035 C CB  . CYS A 1 326 ? 182.137 173.003 198.543 1.00 61.27  ? 326 CYS A CB  1 
ATOM   2036 S SG  . CYS A 1 326 ? 182.578 171.265 198.727 1.00 61.27  ? 326 CYS A SG  1 
ATOM   2037 N N   . ILE A 1 327 ? 181.138 175.886 199.433 1.00 59.75  ? 327 ILE A N   1 
ATOM   2038 C CA  . ILE A 1 327 ? 180.945 177.302 199.137 1.00 59.75  ? 327 ILE A CA  1 
ATOM   2039 C C   . ILE A 1 327 ? 181.653 178.164 200.171 1.00 59.75  ? 327 ILE A C   1 
ATOM   2040 O O   . ILE A 1 327 ? 182.322 179.146 199.823 1.00 59.75  ? 327 ILE A O   1 
ATOM   2041 C CB  . ILE A 1 327 ? 179.443 177.636 199.059 1.00 59.75  ? 327 ILE A CB  1 
ATOM   2042 C CG1 . ILE A 1 327 ? 178.798 176.962 197.849 1.00 59.75  ? 327 ILE A CG1 1 
ATOM   2043 C CG2 . ILE A 1 327 ? 179.230 179.137 198.987 1.00 59.75  ? 327 ILE A CG2 1 
ATOM   2044 C CD1 . ILE A 1 327 ? 179.281 177.489 196.540 1.00 59.75  ? 327 ILE A CD1 1 
ATOM   2045 N N   . GLY A 1 328 ? 181.526 177.816 201.455 1.00 58.69  ? 328 GLY A N   1 
ATOM   2046 C CA  . GLY A 1 328 ? 182.233 178.576 202.471 1.00 58.69  ? 328 GLY A CA  1 
ATOM   2047 C C   . GLY A 1 328 ? 183.736 178.538 202.277 1.00 58.69  ? 328 GLY A C   1 
ATOM   2048 O O   . GLY A 1 328 ? 184.407 179.572 202.314 1.00 58.69  ? 328 GLY A O   1 
ATOM   2049 N N   . LEU A 1 329 ? 184.289 177.345 202.069 1.00 61.80  ? 329 LEU A N   1 
ATOM   2050 C CA  . LEU A 1 329 ? 185.734 177.238 201.914 1.00 61.80  ? 329 LEU A CA  1 
ATOM   2051 C C   . LEU A 1 329 ? 186.216 178.015 200.698 1.00 61.80  ? 329 LEU A C   1 
ATOM   2052 O O   . LEU A 1 329 ? 187.267 178.663 200.745 1.00 61.80  ? 329 LEU A O   1 
ATOM   2053 C CB  . LEU A 1 329 ? 186.151 175.773 201.819 1.00 61.80  ? 329 LEU A CB  1 
ATOM   2054 C CG  . LEU A 1 329 ? 186.531 175.096 203.135 1.00 61.80  ? 329 LEU A CG  1 
ATOM   2055 C CD1 . LEU A 1 329 ? 186.855 173.639 202.884 1.00 61.80  ? 329 LEU A CD1 1 
ATOM   2056 C CD2 . LEU A 1 329 ? 187.711 175.799 203.779 1.00 61.80  ? 329 LEU A CD2 1 
ATOM   2057 N N   . TYR A 1 330 ? 185.461 177.969 199.599 1.00 62.97  ? 330 TYR A N   1 
ATOM   2058 C CA  . TYR A 1 330 ? 185.825 178.743 198.418 1.00 62.97  ? 330 TYR A CA  1 
ATOM   2059 C C   . TYR A 1 330 ? 185.792 180.237 198.705 1.00 62.97  ? 330 TYR A C   1 
ATOM   2060 O O   . TYR A 1 330 ? 186.661 180.981 198.239 1.00 62.97  ? 330 TYR A O   1 
ATOM   2061 C CB  . TYR A 1 330 ? 184.892 178.402 197.259 1.00 62.97  ? 330 TYR A CB  1 
ATOM   2062 C CG  . TYR A 1 330 ? 185.238 179.102 195.965 1.00 62.97  ? 330 TYR A CG  1 
ATOM   2063 C CD1 . TYR A 1 330 ? 186.217 178.597 195.127 1.00 62.97  ? 330 TYR A CD1 1 
ATOM   2064 C CD2 . TYR A 1 330 ? 184.585 180.265 195.583 1.00 62.97  ? 330 TYR A CD2 1 
ATOM   2065 C CE1 . TYR A 1 330 ? 186.538 179.226 193.948 1.00 62.97  ? 330 TYR A CE1 1 
ATOM   2066 C CE2 . TYR A 1 330 ? 184.902 180.903 194.404 1.00 62.97  ? 330 TYR A CE2 1 
ATOM   2067 C CZ  . TYR A 1 330 ? 185.880 180.378 193.590 1.00 62.97  ? 330 TYR A CZ  1 
ATOM   2068 O OH  . TYR A 1 330 ? 186.204 181.003 192.411 1.00 62.97  ? 330 TYR A OH  1 
ATOM   2069 N N   . VAL A 1 331 ? 184.795 180.699 199.462 1.00 63.13  ? 331 VAL A N   1 
ATOM   2070 C CA  . VAL A 1 331 ? 184.667 182.134 199.695 1.00 63.13  ? 331 VAL A CA  1 
ATOM   2071 C C   . VAL A 1 331 ? 185.806 182.653 200.566 1.00 63.13  ? 331 VAL A C   1 
ATOM   2072 O O   . VAL A 1 331 ? 186.458 183.644 200.219 1.00 63.13  ? 331 VAL A O   1 
ATOM   2073 C CB  . VAL A 1 331 ? 183.291 182.459 200.299 1.00 63.13  ? 331 VAL A CB  1 
ATOM   2074 C CG1 . VAL A 1 331 ? 183.311 183.827 200.948 1.00 63.13  ? 331 VAL A CG1 1 
ATOM   2075 C CG2 . VAL A 1 331 ? 182.223 182.402 199.223 1.00 63.13  ? 331 VAL A CG2 1 
ATOM   2076 N N   . GLN A 1 332 ? 186.079 182.003 201.705 1.00 66.11  ? 332 GLN A N   1 
ATOM   2077 C CA  . GLN A 1 332 ? 187.161 182.534 202.541 1.00 66.11  ? 332 GLN A CA  1 
ATOM   2078 C C   . GLN A 1 332 ? 188.548 182.150 202.033 1.00 66.11  ? 332 GLN A C   1 
ATOM   2079 O O   . GLN A 1 332 ? 189.540 182.754 202.456 1.00 66.11  ? 332 GLN A O   1 
ATOM   2080 C CB  . GLN A 1 332 ? 187.049 182.150 204.027 1.00 66.11  ? 332 GLN A CB  1 
ATOM   2081 C CG  . GLN A 1 332 ? 185.871 182.750 204.824 1.00 66.11  ? 332 GLN A CG  1 
ATOM   2082 C CD  . GLN A 1 332 ? 184.567 182.015 204.692 1.00 66.11  ? 332 GLN A CD  1 
ATOM   2083 O OE1 . GLN A 1 332 ? 184.535 180.873 204.283 1.00 66.11  ? 332 GLN A OE1 1 
ATOM   2084 N NE2 . GLN A 1 332 ? 183.473 182.679 205.045 1.00 66.11  ? 332 GLN A NE2 1 
ATOM   2085 N N   . ASP A 1 333 ? 188.659 181.159 201.153 1.00 68.30  ? 333 ASP A N   1 
ATOM   2086 C CA  . ASP A 1 333 ? 189.981 180.729 200.711 1.00 68.30  ? 333 ASP A CA  1 
ATOM   2087 C C   . ASP A 1 333 ? 190.413 181.406 199.414 1.00 68.30  ? 333 ASP A C   1 
ATOM   2088 O O   . ASP A 1 333 ? 191.480 182.024 199.360 1.00 68.30  ? 333 ASP A O   1 
ATOM   2089 C CB  . ASP A 1 333 ? 190.005 179.209 200.546 1.00 68.30  ? 333 ASP A CB  1 
ATOM   2090 C CG  . ASP A 1 333 ? 190.419 178.493 201.815 1.00 68.30  ? 333 ASP A CG  1 
ATOM   2091 O OD1 . ASP A 1 333 ? 190.598 179.171 202.848 1.00 68.30  ? 333 ASP A OD1 1 
ATOM   2092 O OD2 . ASP A 1 333 ? 190.560 177.253 201.783 1.00 68.30  ? 333 ASP A OD2 1 
ATOM   2093 N N   . ILE A 1 334 ? 189.603 181.296 198.363 1.00 67.29  ? 334 ILE A N   1 
ATOM   2094 C CA  . ILE A 1 334 ? 189.977 181.798 197.046 1.00 67.29  ? 334 ILE A CA  1 
ATOM   2095 C C   . ILE A 1 334 ? 189.608 183.269 196.907 1.00 67.29  ? 334 ILE A C   1 
ATOM   2096 O O   . ILE A 1 334 ? 190.461 184.105 196.592 1.00 67.29  ? 334 ILE A O   1 
ATOM   2097 C CB  . ILE A 1 334 ? 189.322 180.965 195.931 1.00 67.29  ? 334 ILE A CB  1 
ATOM   2098 C CG1 . ILE A 1 334 ? 189.650 179.485 196.114 1.00 67.29  ? 334 ILE A CG1 1 
ATOM   2099 C CG2 . ILE A 1 334 ? 189.791 181.446 194.572 1.00 67.29  ? 334 ILE A CG2 1 
ATOM   2100 C CD1 . ILE A 1 334 ? 191.117 179.178 196.005 1.00 67.29  ? 334 ILE A CD1 1 
ATOM   2101 N N   . LEU A 1 335 ? 188.335 183.597 197.138 1.00 66.17  ? 335 LEU A N   1 
ATOM   2102 C CA  . LEU A 1 335 ? 187.879 184.967 196.940 1.00 66.17  ? 335 LEU A CA  1 
ATOM   2103 C C   . LEU A 1 335 ? 188.447 185.929 197.974 1.00 66.17  ? 335 LEU A C   1 
ATOM   2104 O O   . LEU A 1 335 ? 188.493 187.136 197.716 1.00 66.17  ? 335 LEU A O   1 
ATOM   2105 C CB  . LEU A 1 335 ? 186.352 185.022 196.961 1.00 66.17  ? 335 LEU A CB  1 
ATOM   2106 C CG  . LEU A 1 335 ? 185.650 184.458 195.727 1.00 66.17  ? 335 LEU A CG  1 
ATOM   2107 C CD1 . LEU A 1 335 ? 184.163 184.741 195.789 1.00 66.17  ? 335 LEU A CD1 1 
ATOM   2108 C CD2 . LEU A 1 335 ? 186.256 185.029 194.459 1.00 66.17  ? 335 LEU A CD2 1 
ATOM   2109 N N   . GLY A 1 336 ? 188.876 185.432 199.130 1.00 65.82  ? 336 GLY A N   1 
ATOM   2110 C CA  . GLY A 1 336 ? 189.516 186.270 200.122 1.00 65.82  ? 336 GLY A CA  1 
ATOM   2111 C C   . GLY A 1 336 ? 188.588 187.015 201.052 1.00 65.82  ? 336 GLY A C   1 
ATOM   2112 O O   . GLY A 1 336 ? 189.056 187.885 201.794 1.00 65.82  ? 336 GLY A O   1 
ATOM   2113 N N   . TYR A 1 337 ? 187.294 186.715 201.037 1.00 68.26  ? 337 TYR A N   1 
ATOM   2114 C CA  . TYR A 1 337 ? 186.362 187.396 201.924 1.00 68.26  ? 337 TYR A CA  1 
ATOM   2115 C C   . TYR A 1 337 ? 186.611 186.993 203.372 1.00 68.26  ? 337 TYR A C   1 
ATOM   2116 O O   . TYR A 1 337 ? 187.040 185.875 203.666 1.00 68.26  ? 337 TYR A O   1 
ATOM   2117 C CB  . TYR A 1 337 ? 184.915 187.067 201.551 1.00 68.26  ? 337 TYR A CB  1 
ATOM   2118 C CG  . TYR A 1 337 ? 184.470 187.557 200.192 1.00 68.26  ? 337 TYR A CG  1 
ATOM   2119 C CD1 . TYR A 1 337 ? 185.281 188.374 199.420 1.00 68.26  ? 337 TYR A CD1 1 
ATOM   2120 C CD2 . TYR A 1 337 ? 183.231 187.200 199.684 1.00 68.26  ? 337 TYR A CD2 1 
ATOM   2121 C CE1 . TYR A 1 337 ? 184.872 188.817 198.180 1.00 68.26  ? 337 TYR A CE1 1 
ATOM   2122 C CE2 . TYR A 1 337 ? 182.813 187.638 198.447 1.00 68.26  ? 337 TYR A CE2 1 
ATOM   2123 C CZ  . TYR A 1 337 ? 183.636 188.446 197.698 1.00 68.26  ? 337 TYR A CZ  1 
ATOM   2124 O OH  . TYR A 1 337 ? 183.222 188.885 196.463 1.00 68.26  ? 337 TYR A OH  1 
ATOM   2125 N N   . SER A 1 338 ? 186.340 187.921 204.284 1.00 69.14  ? 338 SER A N   1 
ATOM   2126 C CA  . SER A 1 338 ? 186.385 187.611 205.702 1.00 69.14  ? 338 SER A CA  1 
ATOM   2127 C C   . SER A 1 338 ? 185.111 186.872 206.103 1.00 69.14  ? 338 SER A C   1 
ATOM   2128 O O   . SER A 1 338 ? 184.211 186.647 205.291 1.00 69.14  ? 338 SER A O   1 
ATOM   2129 C CB  . SER A 1 338 ? 186.569 188.884 206.523 1.00 69.14  ? 338 SER A CB  1 
ATOM   2130 O OG  . SER A 1 338 ? 185.711 189.913 206.064 1.00 69.14  ? 338 SER A OG  1 
ATOM   2131 N N   . ALA A 1 339 ? 185.036 186.470 207.372 1.00 68.42  ? 339 ALA A N   1 
ATOM   2132 C CA  . ALA A 1 339 ? 183.830 185.806 207.853 1.00 68.42  ? 339 ALA A CA  1 
ATOM   2133 C C   . ALA A 1 339 ? 182.641 186.759 207.860 1.00 68.42  ? 339 ALA A C   1 
ATOM   2134 O O   . ALA A 1 339 ? 181.529 186.377 207.476 1.00 68.42  ? 339 ALA A O   1 
ATOM   2135 C CB  . ALA A 1 339 ? 184.069 185.227 209.245 1.00 68.42  ? 339 ALA A CB  1 
ATOM   2136 N N   . LEU A 1 340 ? 182.857 188.005 208.288 1.00 67.17  ? 340 LEU A N   1 
ATOM   2137 C CA  . LEU A 1 340 ? 181.774 188.982 208.303 1.00 67.17  ? 340 LEU A CA  1 
ATOM   2138 C C   . LEU A 1 340 ? 181.291 189.302 206.894 1.00 67.17  ? 340 LEU A C   1 
ATOM   2139 O O   . LEU A 1 340 ? 180.084 189.431 206.661 1.00 67.17  ? 340 LEU A O   1 
ATOM   2140 C CB  . LEU A 1 340 ? 182.226 190.254 209.017 1.00 67.17  ? 340 LEU A CB  1 
ATOM   2141 C CG  . LEU A 1 340 ? 181.201 191.386 209.081 1.00 67.17  ? 340 LEU A CG  1 
ATOM   2142 C CD1 . LEU A 1 340 ? 180.030 191.006 209.969 1.00 67.17  ? 340 LEU A CD1 1 
ATOM   2143 C CD2 . LEU A 1 340 ? 181.852 192.668 209.570 1.00 67.17  ? 340 LEU A CD2 1 
ATOM   2144 N N   . ARG A 1 341 ? 182.217 189.440 205.942 1.00 67.58  ? 341 ARG A N   1 
ATOM   2145 C CA  . ARG A 1 341 ? 181.823 189.734 204.568 1.00 67.58  ? 341 ARG A CA  1 
ATOM   2146 C C   . ARG A 1 341 ? 180.986 188.608 203.978 1.00 67.58  ? 341 ARG A C   1 
ATOM   2147 O O   . ARG A 1 341 ? 179.967 188.859 203.328 1.00 67.58  ? 341 ARG A O   1 
ATOM   2148 C CB  . ARG A 1 341 ? 183.060 189.985 203.707 1.00 67.58  ? 341 ARG A CB  1 
ATOM   2149 C CG  . ARG A 1 341 ? 183.644 191.378 203.845 1.00 67.58  ? 341 ARG A CG  1 
ATOM   2150 C CD  . ARG A 1 341 ? 184.353 191.801 202.571 1.00 67.58  ? 341 ARG A CD  1 
ATOM   2151 N NE  . ARG A 1 341 ? 183.445 191.837 201.431 1.00 67.58  ? 341 ARG A NE  1 
ATOM   2152 C CZ  . ARG A 1 341 ? 183.829 191.991 200.171 1.00 67.58  ? 341 ARG A CZ  1 
ATOM   2153 N NH1 . ARG A 1 341 ? 185.106 192.121 199.849 1.00 67.58  ? 341 ARG A NH1 1 
ATOM   2154 N NH2 . ARG A 1 341 ? 182.910 192.013 199.211 1.00 67.58  ? 341 ARG A NH2 1 
ATOM   2155 N N   . ALA A 1 342 ? 181.400 187.358 204.193 1.00 64.58  ? 342 ALA A N   1 
ATOM   2156 C CA  . ALA A 1 342 ? 180.626 186.228 203.691 1.00 64.58  ? 342 ALA A CA  1 
ATOM   2157 C C   . ALA A 1 342 ? 179.268 186.141 204.371 1.00 64.58  ? 342 ALA A C   1 
ATOM   2158 O O   . ALA A 1 342 ? 178.255 185.855 203.717 1.00 64.58  ? 342 ALA A O   1 
ATOM   2159 C CB  . ALA A 1 342 ? 181.406 184.931 203.885 1.00 64.58  ? 342 ALA A CB  1 
ATOM   2160 N N   . GLY A 1 343 ? 179.224 186.377 205.682 1.00 63.45  ? 343 GLY A N   1 
ATOM   2161 C CA  . GLY A 1 343 ? 177.948 186.363 206.376 1.00 63.45  ? 343 GLY A CA  1 
ATOM   2162 C C   . GLY A 1 343 ? 176.992 187.416 205.855 1.00 63.45  ? 343 GLY A C   1 
ATOM   2163 O O   . GLY A 1 343 ? 175.795 187.161 205.702 1.00 63.45  ? 343 GLY A O   1 
ATOM   2164 N N   . VAL A 1 344 ? 177.505 188.615 205.575 1.00 63.33  ? 344 VAL A N   1 
ATOM   2165 C CA  . VAL A 1 344 ? 176.665 189.675 205.028 1.00 63.33  ? 344 VAL A CA  1 
ATOM   2166 C C   . VAL A 1 344 ? 176.232 189.338 203.605 1.00 63.33  ? 344 VAL A C   1 
ATOM   2167 O O   . VAL A 1 344 ? 175.094 189.612 203.207 1.00 63.33  ? 344 VAL A O   1 
ATOM   2168 C CB  . VAL A 1 344 ? 177.404 191.023 205.101 1.00 63.33  ? 344 VAL A CB  1 
ATOM   2169 C CG1 . VAL A 1 344 ? 176.712 192.065 204.245 1.00 63.33  ? 344 VAL A CG1 1 
ATOM   2170 C CG2 . VAL A 1 344 ? 177.491 191.494 206.540 1.00 63.33  ? 344 VAL A CG2 1 
ATOM   2171 N N   . GLY A 1 345 ? 177.122 188.729 202.819 1.00 64.35  ? 345 GLY A N   1 
ATOM   2172 C CA  . GLY A 1 345 ? 176.790 188.396 201.446 1.00 64.35  ? 345 GLY A CA  1 
ATOM   2173 C C   . GLY A 1 345 ? 175.865 187.212 201.283 1.00 64.35  ? 345 GLY A C   1 
ATOM   2174 O O   . GLY A 1 345 ? 175.287 187.040 200.206 1.00 64.35  ? 345 GLY A O   1 
ATOM   2175 N N   . PHE A 1 346 ? 175.718 186.386 202.315 1.00 61.86  ? 346 PHE A N   1 
ATOM   2176 C CA  . PHE A 1 346 ? 174.829 185.233 202.240 1.00 61.86  ? 346 PHE A CA  1 
ATOM   2177 C C   . PHE A 1 346 ? 173.385 185.550 202.620 1.00 61.86  ? 346 PHE A C   1 
ATOM   2178 O O   . PHE A 1 346 ? 172.549 184.643 202.614 1.00 61.86  ? 346 PHE A O   1 
ATOM   2179 C CB  . PHE A 1 346 ? 175.359 184.104 203.128 1.00 61.86  ? 346 PHE A CB  1 
ATOM   2180 C CG  . PHE A 1 346 ? 176.540 183.382 202.547 1.00 61.86  ? 346 PHE A CG  1 
ATOM   2181 C CD1 . PHE A 1 346 ? 176.720 183.312 201.178 1.00 61.86  ? 346 PHE A CD1 1 
ATOM   2182 C CD2 . PHE A 1 346 ? 177.471 182.776 203.370 1.00 61.86  ? 346 PHE A CD2 1 
ATOM   2183 C CE1 . PHE A 1 346 ? 177.803 182.652 200.641 1.00 61.86  ? 346 PHE A CE1 1 
ATOM   2184 C CE2 . PHE A 1 346 ? 178.557 182.114 202.837 1.00 61.86  ? 346 PHE A CE2 1 
ATOM   2185 C CZ  . PHE A 1 346 ? 178.722 182.052 201.472 1.00 61.86  ? 346 PHE A CZ  1 
ATOM   2186 N N   . ILE A 1 347 ? 173.075 186.805 202.960 1.00 62.29  ? 347 ILE A N   1 
ATOM   2187 C CA  . ILE A 1 347 ? 171.686 187.172 203.264 1.00 62.29  ? 347 ILE A CA  1 
ATOM   2188 C C   . ILE A 1 347 ? 170.757 186.976 202.072 1.00 62.29  ? 347 ILE A C   1 
ATOM   2189 O O   . ILE A 1 347 ? 169.621 186.505 202.270 1.00 62.29  ? 347 ILE A O   1 
ATOM   2190 C CB  . ILE A 1 347 ? 171.631 188.592 203.843 1.00 62.29  ? 347 ILE A CB  1 
ATOM   2191 C CG1 . ILE A 1 347 ? 172.566 188.708 205.046 1.00 62.29  ? 347 ILE A CG1 1 
ATOM   2192 C CG2 . ILE A 1 347 ? 170.211 188.955 204.240 1.00 62.29  ? 347 ILE A CG2 1 
ATOM   2193 C CD1 . ILE A 1 347 ? 172.486 190.035 205.755 1.00 62.29  ? 347 ILE A CD1 1 
ATOM   2194 N N   . PRO A 1 348 ? 171.129 187.331 200.834 1.00 62.21  ? 348 PRO A N   1 
ATOM   2195 C CA  . PRO A 1 348 ? 170.232 187.041 199.705 1.00 62.21  ? 348 PRO A CA  1 
ATOM   2196 C C   . PRO A 1 348 ? 169.845 185.580 199.595 1.00 62.21  ? 348 PRO A C   1 
ATOM   2197 O O   . PRO A 1 348 ? 168.737 185.285 199.132 1.00 62.21  ? 348 PRO A O   1 
ATOM   2198 C CB  . PRO A 1 348 ? 171.046 187.502 198.490 1.00 62.21  ? 348 PRO A CB  1 
ATOM   2199 C CG  . PRO A 1 348 ? 171.885 188.590 199.016 1.00 62.21  ? 348 PRO A CG  1 
ATOM   2200 C CD  . PRO A 1 348 ? 172.253 188.189 200.413 1.00 62.21  ? 348 PRO A CD  1 
ATOM   2201 N N   . PHE A 1 349 ? 170.713 184.653 200.007 1.00 62.79  ? 349 PHE A N   1 
ATOM   2202 C CA  . PHE A 1 349 ? 170.307 183.253 200.043 1.00 62.79  ? 349 PHE A CA  1 
ATOM   2203 C C   . PHE A 1 349 ? 169.147 183.047 201.004 1.00 62.79  ? 349 PHE A C   1 
ATOM   2204 O O   . PHE A 1 349 ? 168.203 182.314 200.697 1.00 62.79  ? 349 PHE A O   1 
ATOM   2205 C CB  . PHE A 1 349 ? 171.476 182.355 200.439 1.00 62.79  ? 349 PHE A CB  1 
ATOM   2206 C CG  . PHE A 1 349 ? 171.062 180.953 200.781 1.00 62.79  ? 349 PHE A CG  1 
ATOM   2207 C CD1 . PHE A 1 349 ? 170.729 180.055 199.782 1.00 62.79  ? 349 PHE A CD1 1 
ATOM   2208 C CD2 . PHE A 1 349 ? 170.987 180.538 202.098 1.00 62.79  ? 349 PHE A CD2 1 
ATOM   2209 C CE1 . PHE A 1 349 ? 170.338 178.768 200.091 1.00 62.79  ? 349 PHE A CE1 1 
ATOM   2210 C CE2 . PHE A 1 349 ? 170.597 179.252 202.411 1.00 62.79  ? 349 PHE A CE2 1 
ATOM   2211 C CZ  . PHE A 1 349 ? 170.273 178.367 201.405 1.00 62.79  ? 349 PHE A CZ  1 
ATOM   2212 N N   . VAL A 1 350 ? 169.203 183.681 202.177 1.00 62.21  ? 350 VAL A N   1 
ATOM   2213 C CA  . VAL A 1 350 ? 168.117 183.546 203.145 1.00 62.21  ? 350 VAL A CA  1 
ATOM   2214 C C   . VAL A 1 350 ? 166.825 184.117 202.578 1.00 62.21  ? 350 VAL A C   1 
ATOM   2215 O O   . VAL A 1 350 ? 165.752 183.518 202.718 1.00 62.21  ? 350 VAL A O   1 
ATOM   2216 C CB  . VAL A 1 350 ? 168.496 184.219 204.476 1.00 62.21  ? 350 VAL A CB  1 
ATOM   2217 C CG1 . VAL A 1 350 ? 167.371 184.073 205.478 1.00 62.21  ? 350 VAL A CG1 1 
ATOM   2218 C CG2 . VAL A 1 350 ? 169.764 183.615 205.025 1.00 62.21  ? 350 VAL A CG2 1 
ATOM   2219 N N   . ILE A 1 351 ? 166.905 185.278 201.924 1.00 62.45  ? 351 ILE A N   1 
ATOM   2220 C CA  . ILE A 1 351 ? 165.698 185.882 201.360 1.00 62.45  ? 351 ILE A CA  1 
ATOM   2221 C C   . ILE A 1 351 ? 165.111 184.999 200.261 1.00 62.45  ? 351 ILE A C   1 
ATOM   2222 O O   . ILE A 1 351 ? 163.893 184.769 200.209 1.00 62.45  ? 351 ILE A O   1 
ATOM   2223 C CB  . ILE A 1 351 ? 165.998 187.302 200.849 1.00 62.45  ? 351 ILE A CB  1 
ATOM   2224 C CG1 . ILE A 1 351 ? 166.339 188.225 202.019 1.00 62.45  ? 351 ILE A CG1 1 
ATOM   2225 C CG2 . ILE A 1 351 ? 164.817 187.851 200.075 1.00 62.45  ? 351 ILE A CG2 1 
ATOM   2226 C CD1 . ILE A 1 351 ? 166.855 189.578 201.595 1.00 62.45  ? 351 ILE A CD1 1 
ATOM   2227 N N   . ALA A 1 352 ? 165.963 184.488 199.369 1.00 61.19  ? 352 ALA A N   1 
ATOM   2228 C CA  . ALA A 1 352 ? 165.484 183.634 198.288 1.00 61.19  ? 352 ALA A CA  1 
ATOM   2229 C C   . ALA A 1 352 ? 164.884 182.341 198.825 1.00 61.19  ? 352 ALA A C   1 
ATOM   2230 O O   . ALA A 1 352 ? 163.855 181.869 198.325 1.00 61.19  ? 352 ALA A O   1 
ATOM   2231 C CB  . ALA A 1 352 ? 166.623 183.333 197.317 1.00 61.19  ? 352 ALA A CB  1 
ATOM   2232 N N   . MET A 1 353 ? 165.517 181.748 199.839 1.00 62.00  ? 353 MET A N   1 
ATOM   2233 C CA  . MET A 1 353 ? 164.974 180.537 200.439 1.00 62.00  ? 353 MET A CA  1 
ATOM   2234 C C   . MET A 1 353 ? 163.632 180.809 201.101 1.00 62.00  ? 353 MET A C   1 
ATOM   2235 O O   . MET A 1 353 ? 162.721 179.981 201.026 1.00 62.00  ? 353 MET A O   1 
ATOM   2236 C CB  . MET A 1 353 ? 165.967 179.957 201.445 1.00 62.00  ? 353 MET A CB  1 
ATOM   2237 C CG  . MET A 1 353 ? 165.467 178.713 202.151 1.00 62.00  ? 353 MET A CG  1 
ATOM   2238 S SD  . MET A 1 353 ? 166.787 177.571 202.583 1.00 62.00  ? 353 MET A SD  1 
ATOM   2239 C CE  . MET A 1 353 ? 165.867 176.334 203.490 1.00 62.00  ? 353 MET A CE  1 
ATOM   2240 N N   . GLY A 1 354 ? 163.491 181.960 201.759 1.00 60.93  ? 354 GLY A N   1 
ATOM   2241 C CA  . GLY A 1 354 ? 162.202 182.316 202.326 1.00 60.93  ? 354 GLY A CA  1 
ATOM   2242 C C   . GLY A 1 354 ? 161.122 182.449 201.270 1.00 60.93  ? 354 GLY A C   1 
ATOM   2243 O O   . GLY A 1 354 ? 159.996 181.979 201.455 1.00 60.93  ? 354 GLY A O   1 
ATOM   2244 N N   . ILE A 1 355 ? 161.455 183.084 200.143 1.00 60.78  ? 355 ILE A N   1 
ATOM   2245 C CA  . ILE A 1 355 ? 160.493 183.208 199.048 1.00 60.78  ? 355 ILE A CA  1 
ATOM   2246 C C   . ILE A 1 355 ? 160.090 181.829 198.536 1.00 60.78  ? 355 ILE A C   1 
ATOM   2247 O O   . ILE A 1 355 ? 158.905 181.549 198.308 1.00 60.78  ? 355 ILE A O   1 
ATOM   2248 C CB  . ILE A 1 355 ? 161.073 184.078 197.918 1.00 60.78  ? 355 ILE A CB  1 
ATOM   2249 C CG1 . ILE A 1 355 ? 161.246 185.522 198.388 1.00 60.78  ? 355 ILE A CG1 1 
ATOM   2250 C CG2 . ILE A 1 355 ? 160.186 184.017 196.687 1.00 60.78  ? 355 ILE A CG2 1 
ATOM   2251 C CD1 . ILE A 1 355 ? 162.265 186.301 197.591 1.00 60.78  ? 355 ILE A CD1 1 
ATOM   2252 N N   . GLY A 1 356 ? 161.073 180.947 198.349 1.00 59.41  ? 356 GLY A N   1 
ATOM   2253 C CA  . GLY A 1 356 ? 160.772 179.608 197.865 1.00 59.41  ? 356 GLY A CA  1 
ATOM   2254 C C   . GLY A 1 356 ? 159.908 178.813 198.825 1.00 59.41  ? 356 GLY A C   1 
ATOM   2255 O O   . GLY A 1 356 ? 158.977 178.119 198.408 1.00 59.41  ? 356 GLY A O   1 
ATOM   2256 N N   . LEU A 1 357 ? 160.208 178.896 200.124 1.00 58.25  ? 357 LEU A N   1 
ATOM   2257 C CA  . LEU A 1 357 ? 159.398 178.200 201.118 1.00 58.25  ? 357 LEU A CA  1 
ATOM   2258 C C   . LEU A 1 357 ? 157.975 178.737 201.137 1.00 58.25  ? 357 LEU A C   1 
ATOM   2259 O O   . LEU A 1 357 ? 157.014 177.965 201.239 1.00 58.25  ? 357 LEU A O   1 
ATOM   2260 C CB  . LEU A 1 357 ? 160.030 178.329 202.504 1.00 58.25  ? 357 LEU A CB  1 
ATOM   2261 C CG  . LEU A 1 357 ? 161.425 177.754 202.749 1.00 58.25  ? 357 LEU A CG  1 
ATOM   2262 C CD1 . LEU A 1 357 ? 161.949 178.246 204.075 1.00 58.25  ? 357 LEU A CD1 1 
ATOM   2263 C CD2 . LEU A 1 357 ? 161.432 176.243 202.713 1.00 58.25  ? 357 LEU A CD2 1 
ATOM   2264 N N   . GLY A 1 358 ? 157.818 180.059 201.046 1.00 60.35  ? 358 GLY A N   1 
ATOM   2265 C CA  . GLY A 1 358 ? 156.484 180.633 201.015 1.00 60.35  ? 358 GLY A CA  1 
ATOM   2266 C C   . GLY A 1 358 ? 155.688 180.194 199.802 1.00 60.35  ? 358 GLY A C   1 
ATOM   2267 O O   . GLY A 1 358 ? 154.490 179.922 199.899 1.00 60.35  ? 358 GLY A O   1 
ATOM   2268 N N   . VAL A 1 359 ? 156.341 180.125 198.641 1.00 61.38  ? 359 VAL A N   1 
ATOM   2269 C CA  . VAL A 1 359 ? 155.660 179.657 197.438 1.00 61.38  ? 359 VAL A CA  1 
ATOM   2270 C C   . VAL A 1 359 ? 155.265 178.190 197.575 1.00 61.38  ? 359 VAL A C   1 
ATOM   2271 O O   . VAL A 1 359 ? 154.138 177.800 197.240 1.00 61.38  ? 359 VAL A O   1 
ATOM   2272 C CB  . VAL A 1 359 ? 156.547 179.893 196.202 1.00 61.38  ? 359 VAL A CB  1 
ATOM   2273 C CG1 . VAL A 1 359 ? 156.080 179.039 195.036 1.00 61.38  ? 359 VAL A CG1 1 
ATOM   2274 C CG2 . VAL A 1 359 ? 156.546 181.362 195.826 1.00 61.38  ? 359 VAL A CG2 1 
ATOM   2275 N N   . SER A 1 360 ? 156.179 177.354 198.073 1.00 61.19  ? 360 SER A N   1 
ATOM   2276 C CA  . SER A 1 360 ? 155.915 175.920 198.119 1.00 61.19  ? 360 SER A CA  1 
ATOM   2277 C C   . SER A 1 360 ? 154.854 175.574 199.156 1.00 61.19  ? 360 SER A C   1 
ATOM   2278 O O   . SER A 1 360 ? 154.046 174.664 198.939 1.00 61.19  ? 360 SER A O   1 
ATOM   2279 C CB  . SER A 1 360 ? 157.207 175.158 198.399 1.00 61.19  ? 360 SER A CB  1 
ATOM   2280 O OG  . SER A 1 360 ? 157.000 173.763 198.291 1.00 61.19  ? 360 SER A OG  1 
ATOM   2281 N N   . SER A 1 361 ? 154.842 176.274 200.294 1.00 62.24  ? 361 SER A N   1 
ATOM   2282 C CA  . SER A 1 361 ? 153.838 175.994 201.315 1.00 62.24  ? 361 SER A CA  1 
ATOM   2283 C C   . SER A 1 361 ? 152.430 176.293 200.826 1.00 62.24  ? 361 SER A C   1 
ATOM   2284 O O   . SER A 1 361 ? 151.465 175.764 201.385 1.00 62.24  ? 361 SER A O   1 
ATOM   2285 C CB  . SER A 1 361 ? 154.129 176.797 202.582 1.00 62.24  ? 361 SER A CB  1 
ATOM   2286 O OG  . SER A 1 361 ? 153.777 178.157 202.415 1.00 62.24  ? 361 SER A OG  1 
ATOM   2287 N N   . GLN A 1 362 ? 152.292 177.131 199.801 1.00 64.69  ? 362 GLN A N   1 
ATOM   2288 C CA  . GLN A 1 362 ? 151.002 177.365 199.170 1.00 64.69  ? 362 GLN A CA  1 
ATOM   2289 C C   . GLN A 1 362 ? 150.741 176.407 198.019 1.00 64.69  ? 362 GLN A C   1 
ATOM   2290 O O   . GLN A 1 362 ? 149.592 176.007 197.803 1.00 64.69  ? 362 GLN A O   1 
ATOM   2291 C CB  . GLN A 1 362 ? 150.919 178.805 198.657 1.00 64.69  ? 362 GLN A CB  1 
ATOM   2292 C CG  . GLN A 1 362 ? 150.981 179.867 199.742 1.00 64.69  ? 362 GLN A CG  1 
ATOM   2293 C CD  . GLN A 1 362 ? 149.821 179.786 200.713 1.00 64.69  ? 362 GLN A CD  1 
ATOM   2294 O OE1 . GLN A 1 362 ? 149.992 179.411 201.873 1.00 64.69  ? 362 GLN A OE1 1 
ATOM   2295 N NE2 . GLN A 1 362 ? 148.630 180.140 200.243 1.00 64.69  ? 362 GLN A NE2 1 
ATOM   2296 N N   . LEU A 1 363 ? 151.783 176.029 197.277 1.00 64.66  ? 363 LEU A N   1 
ATOM   2297 C CA  . LEU A 1 363 ? 151.608 175.162 196.117 1.00 64.66  ? 363 LEU A CA  1 
ATOM   2298 C C   . LEU A 1 363 ? 151.405 173.695 196.476 1.00 64.66  ? 363 LEU A C   1 
ATOM   2299 O O   . LEU A 1 363 ? 150.874 172.945 195.651 1.00 64.66  ? 363 LEU A O   1 
ATOM   2300 C CB  . LEU A 1 363 ? 152.811 175.286 195.181 1.00 64.66  ? 363 LEU A CB  1 
ATOM   2301 C CG  . LEU A 1 363 ? 152.779 176.430 194.170 1.00 64.66  ? 363 LEU A CG  1 
ATOM   2302 C CD1 . LEU A 1 363 ? 153.990 176.361 193.258 1.00 64.66  ? 363 LEU A CD1 1 
ATOM   2303 C CD2 . LEU A 1 363 ? 151.494 176.391 193.364 1.00 64.66  ? 363 LEU A CD2 1 
ATOM   2304 N N   . VAL A 1 364 ? 151.814 173.261 197.671 1.00 63.93  ? 364 VAL A N   1 
ATOM   2305 C CA  . VAL A 1 364 ? 151.732 171.843 198.016 1.00 63.93  ? 364 VAL A CA  1 
ATOM   2306 C C   . VAL A 1 364 ? 150.309 171.321 198.126 1.00 63.93  ? 364 VAL A C   1 
ATOM   2307 O O   . VAL A 1 364 ? 150.117 170.104 198.223 1.00 63.93  ? 364 VAL A O   1 
ATOM   2308 C CB  . VAL A 1 364 ? 152.459 171.534 199.340 1.00 63.93  ? 364 VAL A CB  1 
ATOM   2309 C CG1 . VAL A 1 364 ? 153.959 171.554 199.142 1.00 63.93  ? 364 VAL A CG1 1 
ATOM   2310 C CG2 . VAL A 1 364 ? 152.046 172.522 200.412 1.00 63.93  ? 364 VAL A CG2 1 
ATOM   2311 N N   . SER A 1 365 ? 149.306 172.196 198.125 1.00 66.75  ? 365 SER A N   1 
ATOM   2312 C CA  . SER A 1 365 ? 147.922 171.750 198.211 1.00 66.75  ? 365 SER A CA  1 
ATOM   2313 C C   . SER A 1 365 ? 147.332 171.370 196.859 1.00 66.75  ? 365 SER A C   1 
ATOM   2314 O O   . SER A 1 365 ? 146.225 170.823 196.820 1.00 66.75  ? 365 SER A O   1 
ATOM   2315 C CB  . SER A 1 365 ? 147.062 172.835 198.859 1.00 66.75  ? 365 SER A CB  1 
ATOM   2316 O OG  . SER A 1 365 ? 147.084 174.023 198.090 1.00 66.75  ? 365 SER A OG  1 
ATOM   2317 N N   . ARG A 1 366 ? 148.034 171.639 195.763 1.00 71.01  ? 366 ARG A N   1 
ATOM   2318 C CA  . ARG A 1 366 ? 147.548 171.342 194.421 1.00 71.01  ? 366 ARG A CA  1 
ATOM   2319 C C   . ARG A 1 366 ? 148.433 170.372 193.659 1.00 71.01  ? 366 ARG A C   1 
ATOM   2320 O O   . ARG A 1 366 ? 147.922 169.553 192.892 1.00 71.01  ? 366 ARG A O   1 
ATOM   2321 C CB  . ARG A 1 366 ? 147.415 172.639 193.609 1.00 71.01  ? 366 ARG A CB  1 
ATOM   2322 C CG  . ARG A 1 366 ? 147.076 173.860 194.441 1.00 71.01  ? 366 ARG A CG  1 
ATOM   2323 C CD  . ARG A 1 366 ? 147.103 175.124 193.602 1.00 71.01  ? 366 ARG A CD  1 
ATOM   2324 N NE  . ARG A 1 366 ? 147.102 176.325 194.429 1.00 71.01  ? 366 ARG A NE  1 
ATOM   2325 C CZ  . ARG A 1 366 ? 147.121 177.563 193.955 1.00 71.01  ? 366 ARG A CZ  1 
ATOM   2326 N NH1 . ARG A 1 366 ? 147.134 177.804 192.654 1.00 71.01  ? 366 ARG A NH1 1 
ATOM   2327 N NH2 . ARG A 1 366 ? 147.127 178.584 194.806 1.00 71.01  ? 366 ARG A NH2 1 
ATOM   2328 N N   . PHE A 1 367 ? 149.747 170.441 193.846 1.00 67.73  ? 367 PHE A N   1 
ATOM   2329 C CA  . PHE A 1 367 ? 150.694 169.615 193.116 1.00 67.73  ? 367 PHE A CA  1 
ATOM   2330 C C   . PHE A 1 367 ? 151.312 168.572 194.037 1.00 67.73  ? 367 PHE A C   1 
ATOM   2331 O O   . PHE A 1 367 ? 151.500 168.806 195.233 1.00 67.73  ? 367 PHE A O   1 
ATOM   2332 C CB  . PHE A 1 367 ? 151.800 170.468 192.489 1.00 67.73  ? 367 PHE A CB  1 
ATOM   2333 C CG  . PHE A 1 367 ? 151.307 171.444 191.462 1.00 67.73  ? 367 PHE A CG  1 
ATOM   2334 C CD1 . PHE A 1 367 ? 150.830 171.003 190.240 1.00 67.73  ? 367 PHE A CD1 1 
ATOM   2335 C CD2 . PHE A 1 367 ? 151.323 172.803 191.715 1.00 67.73  ? 367 PHE A CD2 1 
ATOM   2336 C CE1 . PHE A 1 367 ? 150.377 171.900 189.295 1.00 67.73  ? 367 PHE A CE1 1 
ATOM   2337 C CE2 . PHE A 1 367 ? 150.872 173.703 190.773 1.00 67.73  ? 367 PHE A CE2 1 
ATOM   2338 C CZ  . PHE A 1 367 ? 150.399 173.251 189.563 1.00 67.73  ? 367 PHE A CZ  1 
ATOM   2339 N N   . SER A 1 368 ? 151.625 167.415 193.462 1.00 67.32  ? 368 SER A N   1 
ATOM   2340 C CA  . SER A 1 368 ? 152.234 166.340 194.223 1.00 67.32  ? 368 SER A CA  1 
ATOM   2341 C C   . SER A 1 368 ? 153.654 166.722 194.638 1.00 67.32  ? 368 SER A C   1 
ATOM   2342 O O   . SER A 1 368 ? 154.284 167.572 194.004 1.00 67.32  ? 368 SER A O   1 
ATOM   2343 C CB  . SER A 1 368 ? 152.256 165.057 193.399 1.00 67.32  ? 368 SER A CB  1 
ATOM   2344 O OG  . SER A 1 368 ? 153.045 165.215 192.235 1.00 67.32  ? 368 SER A OG  1 
ATOM   2345 N N   . PRO A 1 369 ? 154.174 166.121 195.713 1.00 65.23  ? 369 PRO A N   1 
ATOM   2346 C CA  . PRO A 1 369 ? 155.540 166.460 196.147 1.00 65.23  ? 369 PRO A CA  1 
ATOM   2347 C C   . PRO A 1 369 ? 156.602 166.189 195.095 1.00 65.23  ? 369 PRO A C   1 
ATOM   2348 O O   . PRO A 1 369 ? 157.615 166.900 195.054 1.00 65.23  ? 369 PRO A O   1 
ATOM   2349 C CB  . PRO A 1 369 ? 155.739 165.575 197.385 1.00 65.23  ? 369 PRO A CB  1 
ATOM   2350 C CG  . PRO A 1 369 ? 154.364 165.280 197.864 1.00 65.23  ? 369 PRO A CG  1 
ATOM   2351 C CD  . PRO A 1 369 ? 153.524 165.178 196.637 1.00 65.23  ? 369 PRO A CD  1 
ATOM   2352 N N   . ARG A 1 370 ? 156.399 165.181 194.244 1.00 63.71  ? 370 ARG A N   1 
ATOM   2353 C CA  . ARG A 1 370 ? 157.391 164.851 193.226 1.00 63.71  ? 370 ARG A CA  1 
ATOM   2354 C C   . ARG A 1 370 ? 157.618 166.013 192.266 1.00 63.71  ? 370 ARG A C   1 
ATOM   2355 O O   . ARG A 1 370 ? 158.766 166.348 191.951 1.00 63.71  ? 370 ARG A O   1 
ATOM   2356 C CB  . ARG A 1 370 ? 156.956 163.598 192.467 1.00 63.71  ? 370 ARG A CB  1 
ATOM   2357 C CG  . ARG A 1 370 ? 157.876 163.212 191.326 1.00 63.71  ? 370 ARG A CG  1 
ATOM   2358 C CD  . ARG A 1 370 ? 157.569 161.822 190.784 1.00 63.71  ? 370 ARG A CD  1 
ATOM   2359 N NE  . ARG A 1 370 ? 156.206 161.693 190.283 1.00 63.71  ? 370 ARG A NE  1 
ATOM   2360 C CZ  . ARG A 1 370 ? 155.334 160.789 190.707 1.00 63.71  ? 370 ARG A CZ  1 
ATOM   2361 N NH1 . ARG A 1 370 ? 155.654 159.899 191.630 1.00 63.71  ? 370 ARG A NH1 1 
ATOM   2362 N NH2 . ARG A 1 370 ? 154.111 160.773 190.186 1.00 63.71  ? 370 ARG A NH2 1 
ATOM   2363 N N   . VAL A 1 371 ? 156.540 166.652 191.806 1.00 63.11  ? 371 VAL A N   1 
ATOM   2364 C CA  . VAL A 1 371 ? 156.669 167.734 190.833 1.00 63.11  ? 371 VAL A CA  1 
ATOM   2365 C C   . VAL A 1 371 ? 157.428 168.911 191.435 1.00 63.11  ? 371 VAL A C   1 
ATOM   2366 O O   . VAL A 1 371 ? 158.327 169.483 190.805 1.00 63.11  ? 371 VAL A O   1 
ATOM   2367 C CB  . VAL A 1 371 ? 155.281 168.161 190.326 1.00 63.11  ? 371 VAL A CB  1 
ATOM   2368 C CG1 . VAL A 1 371 ? 155.408 169.270 189.301 1.00 63.11  ? 371 VAL A CG1 1 
ATOM   2369 C CG2 . VAL A 1 371 ? 154.551 166.970 189.739 1.00 63.11  ? 371 VAL A CG2 1 
ATOM   2370 N N   . LEU A 1 372 ? 157.072 169.294 192.663 1.00 61.64  ? 372 LEU A N   1 
ATOM   2371 C CA  . LEU A 1 372 ? 157.732 170.426 193.304 1.00 61.64  ? 372 LEU A CA  1 
ATOM   2372 C C   . LEU A 1 372 ? 159.198 170.127 193.583 1.00 61.64  ? 372 LEU A C   1 
ATOM   2373 O O   . LEU A 1 372 ? 160.064 170.994 193.395 1.00 61.64  ? 372 LEU A O   1 
ATOM   2374 C CB  . LEU A 1 372 ? 156.999 170.796 194.591 1.00 61.64  ? 372 LEU A CB  1 
ATOM   2375 C CG  . LEU A 1 372 ? 155.525 171.163 194.417 1.00 61.64  ? 372 LEU A CG  1 
ATOM   2376 C CD1 . LEU A 1 372 ? 154.733 170.775 195.645 1.00 61.64  ? 372 LEU A CD1 1 
ATOM   2377 C CD2 . LEU A 1 372 ? 155.370 172.643 194.125 1.00 61.64  ? 372 LEU A CD2 1 
ATOM   2378 N N   . THR A 1 373 ? 159.498 168.906 194.032 1.00 60.42  ? 373 THR A N   1 
ATOM   2379 C CA  . THR A 1 373 ? 160.887 168.527 194.264 1.00 60.42  ? 373 THR A CA  1 
ATOM   2380 C C   . THR A 1 373 ? 161.692 168.592 192.972 1.00 60.42  ? 373 THR A C   1 
ATOM   2381 O O   . THR A 1 373 ? 162.815 169.110 192.952 1.00 60.42  ? 373 THR A O   1 
ATOM   2382 C CB  . THR A 1 373 ? 160.955 167.126 194.872 1.00 60.42  ? 373 THR A CB  1 
ATOM   2383 O OG1 . THR A 1 373 ? 160.152 167.078 196.055 1.00 60.42  ? 373 THR A OG1 1 
ATOM   2384 C CG2 . THR A 1 373 ? 162.385 166.769 195.228 1.00 60.42  ? 373 THR A CG2 1 
ATOM   2385 N N   . ILE A 1 374 ? 161.123 168.089 191.874 1.00 62.55  ? 374 ILE A N   1 
ATOM   2386 C CA  . ILE A 1 374 ? 161.834 168.106 190.599 1.00 62.55  ? 374 ILE A CA  1 
ATOM   2387 C C   . ILE A 1 374 ? 162.058 169.536 190.121 1.00 62.55  ? 374 ILE A C   1 
ATOM   2388 O O   . ILE A 1 374 ? 163.131 169.865 189.608 1.00 62.55  ? 374 ILE A O   1 
ATOM   2389 C CB  . ILE A 1 374 ? 161.083 167.264 189.551 1.00 62.55  ? 374 ILE A CB  1 
ATOM   2390 C CG1 . ILE A 1 374 ? 161.058 165.793 189.965 1.00 62.55  ? 374 ILE A CG1 1 
ATOM   2391 C CG2 . ILE A 1 374 ? 161.734 167.404 188.189 1.00 62.55  ? 374 ILE A CG2 1 
ATOM   2392 C CD1 . ILE A 1 374 ? 162.423 165.165 190.066 1.00 62.55  ? 374 ILE A CD1 1 
ATOM   2393 N N   . GLY A 1 375 ? 161.059 170.409 190.276 1.00 60.81  ? 375 GLY A N   1 
ATOM   2394 C CA  . GLY A 1 375 ? 161.236 171.793 189.853 1.00 60.81  ? 375 GLY A CA  1 
ATOM   2395 C C   . GLY A 1 375 ? 162.302 172.523 190.653 1.00 60.81  ? 375 GLY A C   1 
ATOM   2396 O O   . GLY A 1 375 ? 163.164 173.215 190.092 1.00 60.81  ? 375 GLY A O   1 
ATOM   2397 N N   . GLY A 1 376 ? 162.258 172.379 191.980 1.00 61.34  ? 376 GLY A N   1 
ATOM   2398 C CA  . GLY A 1 376 ? 163.281 172.994 192.808 1.00 61.34  ? 376 GLY A CA  1 
ATOM   2399 C C   . GLY A 1 376 ? 164.669 172.474 192.490 1.00 61.34  ? 376 GLY A C   1 
ATOM   2400 O O   . GLY A 1 376 ? 165.633 173.243 192.417 1.00 61.34  ? 376 GLY A O   1 
ATOM   2401 N N   . GLY A 1 377 ? 164.789 171.162 192.282 1.00 62.56  ? 377 GLY A N   1 
ATOM   2402 C CA  . GLY A 1 377 ? 166.068 170.606 191.890 1.00 62.56  ? 377 GLY A CA  1 
ATOM   2403 C C   . GLY A 1 377 ? 166.536 171.078 190.531 1.00 62.56  ? 377 GLY A C   1 
ATOM   2404 O O   . GLY A 1 377 ? 167.737 171.226 190.308 1.00 62.56  ? 377 GLY A O   1 
ATOM   2405 N N   . TYR A 1 378 ? 165.607 171.290 189.599 1.00 61.00  ? 378 TYR A N   1 
ATOM   2406 C CA  . TYR A 1 378 ? 165.962 171.835 188.293 1.00 61.00  ? 378 TYR A CA  1 
ATOM   2407 C C   . TYR A 1 378 ? 166.585 173.216 188.441 1.00 61.00  ? 378 TYR A C   1 
ATOM   2408 O O   . TYR A 1 378 ? 167.638 173.510 187.855 1.00 61.00  ? 378 TYR A O   1 
ATOM   2409 C CB  . TYR A 1 378 ? 164.712 171.886 187.413 1.00 61.00  ? 378 TYR A CB  1 
ATOM   2410 C CG  . TYR A 1 378 ? 164.949 172.200 185.954 1.00 61.00  ? 378 TYR A CG  1 
ATOM   2411 C CD1 . TYR A 1 378 ? 165.381 171.220 185.072 1.00 61.00  ? 378 TYR A CD1 1 
ATOM   2412 C CD2 . TYR A 1 378 ? 164.714 173.472 185.452 1.00 61.00  ? 378 TYR A CD2 1 
ATOM   2413 C CE1 . TYR A 1 378 ? 165.588 171.503 183.738 1.00 61.00  ? 378 TYR A CE1 1 
ATOM   2414 C CE2 . TYR A 1 378 ? 164.918 173.763 184.121 1.00 61.00  ? 378 TYR A CE2 1 
ATOM   2415 C CZ  . TYR A 1 378 ? 165.354 172.776 183.268 1.00 61.00  ? 378 TYR A CZ  1 
ATOM   2416 O OH  . TYR A 1 378 ? 165.558 173.066 181.940 1.00 61.00  ? 378 TYR A OH  1 
ATOM   2417 N N   . LEU A 1 379 ? 165.955 174.072 189.250 1.00 59.54  ? 379 LEU A N   1 
ATOM   2418 C CA  . LEU A 1 379 ? 166.523 175.397 189.490 1.00 59.54  ? 379 LEU A CA  1 
ATOM   2419 C C   . LEU A 1 379 ? 167.894 175.304 190.156 1.00 59.54  ? 379 LEU A C   1 
ATOM   2420 O O   . LEU A 1 379 ? 168.836 176.012 189.769 1.00 59.54  ? 379 LEU A O   1 
ATOM   2421 C CB  . LEU A 1 379 ? 165.568 176.232 190.341 1.00 59.54  ? 379 LEU A CB  1 
ATOM   2422 C CG  . LEU A 1 379 ? 164.332 176.776 189.625 1.00 59.54  ? 379 LEU A CG  1 
ATOM   2423 C CD1 . LEU A 1 379 ? 163.343 177.349 190.623 1.00 59.54  ? 379 LEU A CD1 1 
ATOM   2424 C CD2 . LEU A 1 379 ? 164.728 177.823 188.603 1.00 59.54  ? 379 LEU A CD2 1 
ATOM   2425 N N   . LEU A 1 380 ? 168.027 174.428 191.157 1.00 60.10  ? 380 LEU A N   1 
ATOM   2426 C CA  . LEU A 1 380 ? 169.304 174.288 191.852 1.00 60.10  ? 380 LEU A CA  1 
ATOM   2427 C C   . LEU A 1 380 ? 170.398 173.778 190.919 1.00 60.10  ? 380 LEU A C   1 
ATOM   2428 O O   . LEU A 1 380 ? 171.542 174.242 190.979 1.00 60.10  ? 380 LEU A O   1 
ATOM   2429 C CB  . LEU A 1 380 ? 169.146 173.358 193.054 1.00 60.10  ? 380 LEU A CB  1 
ATOM   2430 C CG  . LEU A 1 380 ? 170.423 173.023 193.824 1.00 60.10  ? 380 LEU A CG  1 
ATOM   2431 C CD1 . LEU A 1 380 ? 171.070 174.284 194.368 1.00 60.10  ? 380 LEU A CD1 1 
ATOM   2432 C CD2 . LEU A 1 380 ? 170.127 172.045 194.944 1.00 60.10  ? 380 LEU A CD2 1 
ATOM   2433 N N   . PHE A 1 381 ? 170.067 172.813 190.059 1.00 61.17  ? 381 PHE A N   1 
ATOM   2434 C CA  . PHE A 1 381 ? 171.039 172.277 189.113 1.00 61.17  ? 381 PHE A CA  1 
ATOM   2435 C C   . PHE A 1 381 ? 171.488 173.343 188.125 1.00 61.17  ? 381 PHE A C   1 
ATOM   2436 O O   . PHE A 1 381 ? 172.675 173.427 187.785 1.00 61.17  ? 381 PHE A O   1 
ATOM   2437 C CB  . PHE A 1 381 ? 170.438 171.082 188.376 1.00 61.17  ? 381 PHE A CB  1 
ATOM   2438 C CG  . PHE A 1 381 ? 171.363 170.453 187.379 1.00 61.17  ? 381 PHE A CG  1 
ATOM   2439 C CD1 . PHE A 1 381 ? 172.442 169.697 187.796 1.00 61.17  ? 381 PHE A CD1 1 
ATOM   2440 C CD2 . PHE A 1 381 ? 171.155 170.620 186.023 1.00 61.17  ? 381 PHE A CD2 1 
ATOM   2441 C CE1 . PHE A 1 381 ? 173.292 169.116 186.879 1.00 61.17  ? 381 PHE A CE1 1 
ATOM   2442 C CE2 . PHE A 1 381 ? 172.003 170.041 185.102 1.00 61.17  ? 381 PHE A CE2 1 
ATOM   2443 C CZ  . PHE A 1 381 ? 173.073 169.289 185.531 1.00 61.17  ? 381 PHE A CZ  1 
ATOM   2444 N N   . GLY A 1 382 ? 170.551 174.163 187.645 1.00 61.73  ? 382 GLY A N   1 
ATOM   2445 C CA  . GLY A 1 382 ? 170.938 175.263 186.778 1.00 61.73  ? 382 GLY A CA  1 
ATOM   2446 C C   . GLY A 1 382 ? 171.877 176.237 187.461 1.00 61.73  ? 382 GLY A C   1 
ATOM   2447 O O   . GLY A 1 382 ? 172.878 176.665 186.877 1.00 61.73  ? 382 GLY A O   1 
ATOM   2448 N N   . ALA A 1 383 ? 171.571 176.593 188.712 1.00 61.76  ? 383 ALA A N   1 
ATOM   2449 C CA  . ALA A 1 383 ? 172.451 177.494 189.453 1.00 61.76  ? 383 ALA A CA  1 
ATOM   2450 C C   . ALA A 1 383 ? 173.837 176.888 189.636 1.00 61.76  ? 383 ALA A C   1 
ATOM   2451 O O   . ALA A 1 383 ? 174.851 177.580 189.485 1.00 61.76  ? 383 ALA A O   1 
ATOM   2452 C CB  . ALA A 1 383 ? 171.834 177.839 190.806 1.00 61.76  ? 383 ALA A CB  1 
ATOM   2453 N N   . MET A 1 384 ? 173.901 175.594 189.961 1.00 61.02  ? 384 MET A N   1 
ATOM   2454 C CA  . MET A 1 384 ? 175.191 174.942 190.166 1.00 61.02  ? 384 MET A CA  1 
ATOM   2455 C C   . MET A 1 384 ? 176.006 174.899 188.880 1.00 61.02  ? 384 MET A C   1 
ATOM   2456 O O   . MET A 1 384 ? 177.221 175.125 188.903 1.00 61.02  ? 384 MET A O   1 
ATOM   2457 C CB  . MET A 1 384 ? 174.987 173.532 190.717 1.00 61.02  ? 384 MET A CB  1 
ATOM   2458 C CG  . MET A 1 384 ? 174.848 173.472 192.225 1.00 61.02  ? 384 MET A CG  1 
ATOM   2459 S SD  . MET A 1 384 ? 175.022 171.802 192.875 1.00 61.02  ? 384 MET A SD  1 
ATOM   2460 C CE  . MET A 1 384 ? 173.410 171.122 192.504 1.00 61.02  ? 384 MET A CE  1 
ATOM   2461 N N   . LEU A 1 385 ? 175.362 174.601 187.748 1.00 60.67  ? 385 LEU A N   1 
ATOM   2462 C CA  . LEU A 1 385 ? 176.084 174.583 186.478 1.00 60.67  ? 385 LEU A CA  1 
ATOM   2463 C C   . LEU A 1 385 ? 176.593 175.971 186.110 1.00 60.67  ? 385 LEU A C   1 
ATOM   2464 O O   . LEU A 1 385 ? 177.736 176.122 185.656 1.00 60.67  ? 385 LEU A O   1 
ATOM   2465 C CB  . LEU A 1 385 ? 175.193 174.028 185.369 1.00 60.67  ? 385 LEU A CB  1 
ATOM   2466 C CG  . LEU A 1 385 ? 175.334 172.533 185.083 1.00 60.67  ? 385 LEU A CG  1 
ATOM   2467 C CD1 . LEU A 1 385 ? 174.554 172.153 183.839 1.00 60.67  ? 385 LEU A CD1 1 
ATOM   2468 C CD2 . LEU A 1 385 ? 176.796 172.153 184.939 1.00 60.67  ? 385 LEU A CD2 1 
ATOM   2469 N N   . TYR A 1 386 ? 175.762 177.000 186.302 1.00 64.46  ? 386 TYR A N   1 
ATOM   2470 C CA  . TYR A 1 386 ? 176.209 178.364 186.034 1.00 64.46  ? 386 TYR A CA  1 
ATOM   2471 C C   . TYR A 1 386 ? 177.400 178.727 186.909 1.00 64.46  ? 386 TYR A C   1 
ATOM   2472 O O   . TYR A 1 386 ? 178.362 179.347 186.443 1.00 64.46  ? 386 TYR A O   1 
ATOM   2473 C CB  . TYR A 1 386 ? 175.066 179.353 186.255 1.00 64.46  ? 386 TYR A CB  1 
ATOM   2474 C CG  . TYR A 1 386 ? 175.443 180.787 185.960 1.00 64.46  ? 386 TYR A CG  1 
ATOM   2475 C CD1 . TYR A 1 386 ? 175.558 181.243 184.654 1.00 64.46  ? 386 TYR A CD1 1 
ATOM   2476 C CD2 . TYR A 1 386 ? 175.700 181.683 186.988 1.00 64.46  ? 386 TYR A CD2 1 
ATOM   2477 C CE1 . TYR A 1 386 ? 175.906 182.552 184.382 1.00 64.46  ? 386 TYR A CE1 1 
ATOM   2478 C CE2 . TYR A 1 386 ? 176.051 182.993 186.724 1.00 64.46  ? 386 TYR A CE2 1 
ATOM   2479 C CZ  . TYR A 1 386 ? 176.151 183.421 185.421 1.00 64.46  ? 386 TYR A CZ  1 
ATOM   2480 O OH  . TYR A 1 386 ? 176.499 184.724 185.155 1.00 64.46  ? 386 TYR A OH  1 
ATOM   2481 N N   . GLY A 1 387 ? 177.349 178.355 188.188 1.00 62.26  ? 387 GLY A N   1 
ATOM   2482 C CA  . GLY A 1 387 ? 178.475 178.623 189.067 1.00 62.26  ? 387 GLY A CA  1 
ATOM   2483 C C   . GLY A 1 387 ? 179.734 177.894 188.644 1.00 62.26  ? 387 GLY A C   1 
ATOM   2484 O O   . GLY A 1 387 ? 180.830 178.450 188.691 1.00 62.26  ? 387 GLY A O   1 
ATOM   2485 N N   . SER A 1 388 ? 179.598 176.637 188.226 1.00 60.74  ? 388 SER A N   1 
ATOM   2486 C CA  . SER A 1 388 ? 180.767 175.873 187.805 1.00 60.74  ? 388 SER A CA  1 
ATOM   2487 C C   . SER A 1 388 ? 181.403 176.466 186.554 1.00 60.74  ? 388 SER A C   1 
ATOM   2488 O O   . SER A 1 388 ? 182.633 176.523 186.446 1.00 60.74  ? 388 SER A O   1 
ATOM   2489 C CB  . SER A 1 388 ? 180.382 174.416 187.567 1.00 60.74  ? 388 SER A CB  1 
ATOM   2490 O OG  . SER A 1 388 ? 181.467 173.690 187.023 1.00 60.74  ? 388 SER A OG  1 
ATOM   2491 N N   . PHE A 1 389 ? 180.586 176.908 185.594 1.00 58.38  ? 389 PHE A N   1 
ATOM   2492 C CA  . PHE A 1 389 ? 181.131 177.334 184.307 1.00 58.38  ? 389 PHE A CA  1 
ATOM   2493 C C   . PHE A 1 389 ? 181.850 178.677 184.400 1.00 58.38  ? 389 PHE A C   1 
ATOM   2494 O O   . PHE A 1 389 ? 182.947 178.833 183.853 1.00 58.38  ? 389 PHE A O   1 
ATOM   2495 C CB  . PHE A 1 389 ? 180.019 177.403 183.262 1.00 58.38  ? 389 PHE A CB  1 
ATOM   2496 C CG  . PHE A 1 389 ? 179.621 176.066 182.709 1.00 58.38  ? 389 PHE A CG  1 
ATOM   2497 C CD1 . PHE A 1 389 ? 180.404 174.950 182.926 1.00 58.38  ? 389 PHE A CD1 1 
ATOM   2498 C CD2 . PHE A 1 389 ? 178.460 175.928 181.972 1.00 58.38  ? 389 PHE A CD2 1 
ATOM   2499 C CE1 . PHE A 1 389 ? 180.038 173.723 182.418 1.00 58.38  ? 389 PHE A CE1 1 
ATOM   2500 C CE2 . PHE A 1 389 ? 178.090 174.703 181.463 1.00 58.38  ? 389 PHE A CE2 1 
ATOM   2501 C CZ  . PHE A 1 389 ? 178.880 173.599 181.686 1.00 58.38  ? 389 PHE A CZ  1 
ATOM   2502 N N   . PHE A 1 390 ? 181.259 179.657 185.082 1.00 62.37  ? 390 PHE A N   1 
ATOM   2503 C CA  . PHE A 1 390 ? 181.692 181.048 184.991 1.00 62.37  ? 390 PHE A CA  1 
ATOM   2504 C C   . PHE A 1 390 ? 182.120 181.617 186.340 1.00 62.37  ? 390 PHE A C   1 
ATOM   2505 O O   . PHE A 1 390 ? 181.725 182.723 186.710 1.00 62.37  ? 390 PHE A O   1 
ATOM   2506 C CB  . PHE A 1 390 ? 180.586 181.922 184.402 1.00 62.37  ? 390 PHE A CB  1 
ATOM   2507 C CG  . PHE A 1 390 ? 180.059 181.440 183.083 1.00 62.37  ? 390 PHE A CG  1 
ATOM   2508 C CD1 . PHE A 1 390 ? 180.795 181.603 181.924 1.00 62.37  ? 390 PHE A CD1 1 
ATOM   2509 C CD2 . PHE A 1 390 ? 178.816 180.838 183.001 1.00 62.37  ? 390 PHE A CD2 1 
ATOM   2510 C CE1 . PHE A 1 390 ? 180.307 181.163 180.712 1.00 62.37  ? 390 PHE A CE1 1 
ATOM   2511 C CE2 . PHE A 1 390 ? 178.323 180.397 181.792 1.00 62.37  ? 390 PHE A CE2 1 
ATOM   2512 C CZ  . PHE A 1 390 ? 179.069 180.560 180.647 1.00 62.37  ? 390 PHE A CZ  1 
ATOM   2513 N N   . MET A 1 391 ? 182.937 180.890 187.098 1.00 69.50  ? 391 MET A N   1 
ATOM   2514 C CA  . MET A 1 391 ? 183.369 181.363 188.408 1.00 69.50  ? 391 MET A CA  1 
ATOM   2515 C C   . MET A 1 391 ? 184.867 181.150 188.558 1.00 69.50  ? 391 MET A C   1 
ATOM   2516 O O   . MET A 1 391 ? 185.359 180.032 188.374 1.00 69.50  ? 391 MET A O   1 
ATOM   2517 C CB  . MET A 1 391 ? 182.622 180.635 189.524 1.00 69.50  ? 391 MET A CB  1 
ATOM   2518 C CG  . MET A 1 391 ? 182.859 181.146 190.928 1.00 69.50  ? 391 MET A CG  1 
ATOM   2519 S SD  . MET A 1 391 ? 182.218 182.811 191.167 1.00 69.50  ? 391 MET A SD  1 
ATOM   2520 C CE  . MET A 1 391 ? 183.226 183.357 192.536 1.00 69.50  ? 391 MET A CE  1 
ATOM   2521 N N   . HIS A 1 392 ? 185.582 182.218 188.897 1.00 74.15  ? 392 HIS A N   1 
ATOM   2522 C CA  . HIS A 1 392 ? 187.009 182.152 189.180 1.00 74.15  ? 392 HIS A CA  1 
ATOM   2523 C C   . HIS A 1 392 ? 187.384 183.390 189.978 1.00 74.15  ? 392 HIS A C   1 
ATOM   2524 O O   . HIS A 1 392 ? 186.596 184.326 190.108 1.00 74.15  ? 392 HIS A O   1 
ATOM   2525 C CB  . HIS A 1 392 ? 187.840 182.042 187.898 1.00 74.15  ? 392 HIS A CB  1 
ATOM   2526 C CG  . HIS A 1 392 ? 187.764 183.251 187.019 1.00 74.15  ? 392 HIS A CG  1 
ATOM   2527 N ND1 . HIS A 1 392 ? 186.602 183.647 186.394 1.00 74.15  ? 392 HIS A ND1 1 
ATOM   2528 C CD2 . HIS A 1 392 ? 188.710 184.151 186.660 1.00 74.15  ? 392 HIS A CD2 1 
ATOM   2529 C CE1 . HIS A 1 392 ? 186.835 184.738 185.686 1.00 74.15  ? 392 HIS A CE1 1 
ATOM   2530 N NE2 . HIS A 1 392 ? 188.106 185.066 185.833 1.00 74.15  ? 392 HIS A NE2 1 
ATOM   2531 N N   . ARG A 1 393 ? 188.598 183.382 190.521 1.00 75.73  ? 393 ARG A N   1 
ATOM   2532 C CA  . ARG A 1 393 ? 189.053 184.509 191.322 1.00 75.73  ? 393 ARG A CA  1 
ATOM   2533 C C   . ARG A 1 393 ? 189.147 185.771 190.478 1.00 75.73  ? 393 ARG A C   1 
ATOM   2534 O O   . ARG A 1 393 ? 189.633 185.743 189.344 1.00 75.73  ? 393 ARG A O   1 
ATOM   2535 C CB  . ARG A 1 393 ? 190.405 184.203 191.960 1.00 75.73  ? 393 ARG A CB  1 
ATOM   2536 C CG  . ARG A 1 393 ? 190.948 185.352 192.788 1.00 75.73  ? 393 ARG A CG  1 
ATOM   2537 C CD  . ARG A 1 393 ? 192.441 185.238 192.976 1.00 75.73  ? 393 ARG A CD  1 
ATOM   2538 N NE  . ARG A 1 393 ? 192.754 184.276 194.023 1.00 75.73  ? 393 ARG A NE  1 
ATOM   2539 C CZ  . ARG A 1 393 ? 193.956 184.105 194.554 1.00 75.73  ? 393 ARG A CZ  1 
ATOM   2540 N NH1 . ARG A 1 393 ? 195.003 184.794 194.130 1.00 75.73  ? 393 ARG A NH1 1 
ATOM   2541 N NH2 . ARG A 1 393 ? 194.110 183.223 195.537 1.00 75.73  ? 393 ARG A NH2 1 
ATOM   2542 N N   . GLY A 1 394 ? 188.684 186.884 191.042 1.00 76.59  ? 394 GLY A N   1 
ATOM   2543 C CA  . GLY A 1 394 ? 188.693 188.158 190.360 1.00 76.59  ? 394 GLY A CA  1 
ATOM   2544 C C   . GLY A 1 394 ? 187.366 188.582 189.774 1.00 76.59  ? 394 GLY A C   1 
ATOM   2545 O O   . GLY A 1 394 ? 187.265 189.710 189.278 1.00 76.59  ? 394 GLY A O   1 
ATOM   2546 N N   . VAL A 1 395 ? 186.352 187.725 189.808 1.00 77.00  ? 395 VAL A N   1 
ATOM   2547 C CA  . VAL A 1 395 ? 185.036 188.083 189.288 1.00 77.00  ? 395 VAL A CA  1 
ATOM   2548 C C   . VAL A 1 395 ? 184.388 189.084 190.236 1.00 77.00  ? 395 VAL A C   1 
ATOM   2549 O O   . VAL A 1 395 ? 184.622 189.030 191.452 1.00 77.00  ? 395 VAL A O   1 
ATOM   2550 C CB  . VAL A 1 395 ? 184.142 186.847 189.107 1.00 77.00  ? 395 VAL A CB  1 
ATOM   2551 C CG1 . VAL A 1 395 ? 184.670 185.966 187.993 1.00 77.00  ? 395 VAL A CG1 1 
ATOM   2552 C CG2 . VAL A 1 395 ? 184.028 186.079 190.405 1.00 77.00  ? 395 VAL A CG2 1 
ATOM   2553 N N   . PRO A 1 396 ? 183.587 190.016 189.732 1.00 79.01  ? 396 PRO A N   1 
ATOM   2554 C CA  . PRO A 1 396 ? 182.841 190.903 190.625 1.00 79.01  ? 396 PRO A CA  1 
ATOM   2555 C C   . PRO A 1 396 ? 181.727 190.155 191.338 1.00 79.01  ? 396 PRO A C   1 
ATOM   2556 O O   . PRO A 1 396 ? 181.232 189.123 190.879 1.00 79.01  ? 396 PRO A O   1 
ATOM   2557 C CB  . PRO A 1 396 ? 182.282 191.976 189.686 1.00 79.01  ? 396 PRO A CB  1 
ATOM   2558 C CG  . PRO A 1 396 ? 182.262 191.339 188.349 1.00 79.01  ? 396 PRO A CG  1 
ATOM   2559 C CD  . PRO A 1 396 ? 183.355 190.320 188.311 1.00 79.01  ? 396 PRO A CD  1 
ATOM   2560 N N   . TYR A 1 397 ? 181.341 190.696 192.493 1.00 77.93  ? 397 TYR A N   1 
ATOM   2561 C CA  . TYR A 1 397 ? 180.322 190.054 193.315 1.00 77.93  ? 397 TYR A CA  1 
ATOM   2562 C C   . TYR A 1 397 ? 178.950 190.113 192.653 1.00 77.93  ? 397 TYR A C   1 
ATOM   2563 O O   . TYR A 1 397 ? 178.262 189.092 192.538 1.00 77.93  ? 397 TYR A O   1 
ATOM   2564 C CB  . TYR A 1 397 ? 180.292 190.716 194.693 1.00 77.93  ? 397 TYR A CB  1 
ATOM   2565 C CG  . TYR A 1 397 ? 179.122 190.331 195.569 1.00 77.93  ? 397 TYR A CG  1 
ATOM   2566 C CD1 . TYR A 1 397 ? 179.085 189.105 196.214 1.00 77.93  ? 397 TYR A CD1 1 
ATOM   2567 C CD2 . TYR A 1 397 ? 178.065 191.206 195.767 1.00 77.93  ? 397 TYR A CD2 1 
ATOM   2568 C CE1 . TYR A 1 397 ? 178.023 188.755 197.020 1.00 77.93  ? 397 TYR A CE1 1 
ATOM   2569 C CE2 . TYR A 1 397 ? 177.000 190.865 196.572 1.00 77.93  ? 397 TYR A CE2 1 
ATOM   2570 C CZ  . TYR A 1 397 ? 176.985 189.640 197.196 1.00 77.93  ? 397 TYR A CZ  1 
ATOM   2571 O OH  . TYR A 1 397 ? 175.922 189.299 197.997 1.00 77.93  ? 397 TYR A OH  1 
ATOM   2572 N N   . PHE A 1 398 ? 178.550 191.302 192.183 1.00 83.31  ? 398 PHE A N   1 
ATOM   2573 C CA  . PHE A 1 398 ? 177.151 191.514 191.809 1.00 83.31  ? 398 PHE A CA  1 
ATOM   2574 C C   . PHE A 1 398 ? 176.700 190.652 190.636 1.00 83.31  ? 398 PHE A C   1 
ATOM   2575 O O   . PHE A 1 398 ? 175.667 189.973 190.762 1.00 83.31  ? 398 PHE A O   1 
ATOM   2576 C CB  . PHE A 1 398 ? 176.906 193.003 191.547 1.00 83.31  ? 398 PHE A CB  1 
ATOM   2577 C CG  . PHE A 1 398 ? 175.471 193.341 191.262 1.00 83.31  ? 398 PHE A CG  1 
ATOM   2578 C CD1 . PHE A 1 398 ? 174.989 193.350 189.962 1.00 83.31  ? 398 PHE A CD1 1 
ATOM   2579 C CD2 . PHE A 1 398 ? 174.601 193.652 192.295 1.00 83.31  ? 398 PHE A CD2 1 
ATOM   2580 C CE1 . PHE A 1 398 ? 173.669 193.661 189.700 1.00 83.31  ? 398 PHE A CE1 1 
ATOM   2581 C CE2 . PHE A 1 398 ? 173.280 193.963 192.039 1.00 83.31  ? 398 PHE A CE2 1 
ATOM   2582 C CZ  . PHE A 1 398 ? 172.813 193.968 190.740 1.00 83.31  ? 398 PHE A CZ  1 
ATOM   2583 N N   . PRO A 1 399 ? 177.379 190.626 189.485 1.00 81.11  ? 399 PRO A N   1 
ATOM   2584 C CA  . PRO A 1 399 ? 176.837 189.832 188.373 1.00 81.11  ? 399 PRO A CA  1 
ATOM   2585 C C   . PRO A 1 399 ? 177.075 188.340 188.509 1.00 81.11  ? 399 PRO A C   1 
ATOM   2586 O O   . PRO A 1 399 ? 176.362 187.556 187.872 1.00 81.11  ? 399 PRO A O   1 
ATOM   2587 C CB  . PRO A 1 399 ? 177.571 190.410 187.158 1.00 81.11  ? 399 PRO A CB  1 
ATOM   2588 C CG  . PRO A 1 399 ? 178.885 190.766 187.722 1.00 81.11  ? 399 PRO A CG  1 
ATOM   2589 C CD  . PRO A 1 399 ? 178.532 191.425 189.031 1.00 81.11  ? 399 PRO A CD  1 
ATOM   2590 N N   . ASN A 1 400 ? 178.046 187.915 189.320 1.00 79.35  ? 400 ASN A N   1 
ATOM   2591 C CA  . ASN A 1 400 ? 178.501 186.533 189.295 1.00 79.35  ? 400 ASN A CA  1 
ATOM   2592 C C   . ASN A 1 400 ? 178.153 185.718 190.532 1.00 79.35  ? 400 ASN A C   1 
ATOM   2593 O O   . ASN A 1 400 ? 178.223 184.487 190.467 1.00 79.35  ? 400 ASN A O   1 
ATOM   2594 C CB  . ASN A 1 400 ? 180.022 186.477 189.089 1.00 79.35  ? 400 ASN A CB  1 
ATOM   2595 C CG  . ASN A 1 400 ? 180.422 186.728 187.650 1.00 79.35  ? 400 ASN A CG  1 
ATOM   2596 O OD1 . ASN A 1 400 ? 180.468 187.870 187.197 1.00 79.35  ? 400 ASN A OD1 1 
ATOM   2597 N ND2 . ASN A 1 400 ? 180.717 185.658 186.924 1.00 79.35  ? 400 ASN A ND2 1 
ATOM   2598 N N   . LEU A 1 401 ? 177.788 186.348 191.647 1.00 72.90  ? 401 LEU A N   1 
ATOM   2599 C CA  . LEU A 1 401 ? 177.516 185.599 192.868 1.00 72.90  ? 401 LEU A CA  1 
ATOM   2600 C C   . LEU A 1 401 ? 176.052 185.600 193.279 1.00 72.90  ? 401 LEU A C   1 
ATOM   2601 O O   . LEU A 1 401 ? 175.507 184.536 193.574 1.00 72.90  ? 401 LEU A O   1 
ATOM   2602 C CB  . LEU A 1 401 ? 178.380 186.127 194.021 1.00 72.90  ? 401 LEU A CB  1 
ATOM   2603 C CG  . LEU A 1 401 ? 179.767 185.487 194.086 1.00 72.90  ? 401 LEU A CG  1 
ATOM   2604 C CD1 . LEU A 1 401 ? 180.655 186.190 195.092 1.00 72.90  ? 401 LEU A CD1 1 
ATOM   2605 C CD2 . LEU A 1 401 ? 179.636 184.014 194.433 1.00 72.90  ? 401 LEU A CD2 1 
ATOM   2606 N N   . VAL A 1 402 ? 175.390 186.759 193.310 1.00 71.36  ? 402 VAL A N   1 
ATOM   2607 C CA  . VAL A 1 402 ? 174.046 186.803 193.882 1.00 71.36  ? 402 VAL A CA  1 
ATOM   2608 C C   . VAL A 1 402 ? 173.063 186.014 193.025 1.00 71.36  ? 402 VAL A C   1 
ATOM   2609 O O   . VAL A 1 402 ? 172.159 185.355 193.551 1.00 71.36  ? 402 VAL A O   1 
ATOM   2610 C CB  . VAL A 1 402 ? 173.578 188.255 194.085 1.00 71.36  ? 402 VAL A CB  1 
ATOM   2611 C CG1 . VAL A 1 402 ? 174.412 188.933 195.145 1.00 71.36  ? 402 VAL A CG1 1 
ATOM   2612 C CG2 . VAL A 1 402 ? 173.617 189.028 192.791 1.00 71.36  ? 402 VAL A CG2 1 
ATOM   2613 N N   . MET A 1 403 ? 173.212 186.067 191.701 1.00 71.24  ? 403 MET A N   1 
ATOM   2614 C CA  . MET A 1 403 ? 172.250 185.390 190.832 1.00 71.24  ? 403 MET A CA  1 
ATOM   2615 C C   . MET A 1 403 ? 172.245 183.878 191.018 1.00 71.24  ? 403 MET A C   1 
ATOM   2616 O O   . MET A 1 403 ? 171.161 183.314 191.256 1.00 71.24  ? 403 MET A O   1 
ATOM   2617 C CB  . MET A 1 403 ? 172.506 185.785 189.374 1.00 71.24  ? 403 MET A CB  1 
ATOM   2618 C CG  . MET A 1 403 ? 172.261 187.254 189.084 1.00 71.24  ? 403 MET A CG  1 
ATOM   2619 S SD  . MET A 1 403 ? 170.538 187.722 189.324 1.00 71.24  ? 403 MET A SD  1 
ATOM   2620 C CE  . MET A 1 403 ? 170.647 189.498 189.141 1.00 71.24  ? 403 MET A CE  1 
ATOM   2621 N N   . PRO A 1 404 ? 173.376 183.162 190.931 1.00 67.80  ? 404 PRO A N   1 
ATOM   2622 C CA  . PRO A 1 404 ? 173.324 181.722 191.231 1.00 67.80  ? 404 PRO A CA  1 
ATOM   2623 C C   . PRO A 1 404 ? 172.888 181.431 192.654 1.00 67.80  ? 404 PRO A C   1 
ATOM   2624 O O   . PRO A 1 404 ? 172.158 180.461 192.885 1.00 67.80  ? 404 PRO A O   1 
ATOM   2625 C CB  . PRO A 1 404 ? 174.760 181.254 190.958 1.00 67.80  ? 404 PRO A CB  1 
ATOM   2626 C CG  . PRO A 1 404 ? 175.587 182.465 191.089 1.00 67.80  ? 404 PRO A CG  1 
ATOM   2627 C CD  . PRO A 1 404 ? 174.742 183.583 190.573 1.00 67.80  ? 404 PRO A CD  1 
ATOM   2628 N N   . ILE A 1 405 ? 173.295 182.263 193.614 1.00 65.87  ? 405 ILE A N   1 
ATOM   2629 C CA  . ILE A 1 405 ? 172.884 182.061 195.001 1.00 65.87  ? 405 ILE A CA  1 
ATOM   2630 C C   . ILE A 1 405 ? 171.377 182.225 195.144 1.00 65.87  ? 405 ILE A C   1 
ATOM   2631 O O   . ILE A 1 405 ? 170.713 181.422 195.806 1.00 65.87  ? 405 ILE A O   1 
ATOM   2632 C CB  . ILE A 1 405 ? 173.650 183.011 195.938 1.00 65.87  ? 405 ILE A CB  1 
ATOM   2633 C CG1 . ILE A 1 405 ? 175.129 182.631 195.995 1.00 65.87  ? 405 ILE A CG1 1 
ATOM   2634 C CG2 . ILE A 1 405 ? 173.045 183.005 197.321 1.00 65.87  ? 405 ILE A CG2 1 
ATOM   2635 C CD1 . ILE A 1 405 ? 175.982 183.651 196.705 1.00 65.87  ? 405 ILE A CD1 1 
ATOM   2636 N N   . VAL A 1 406 ? 170.811 183.262 194.523 1.00 63.33  ? 406 VAL A N   1 
ATOM   2637 C CA  . VAL A 1 406 ? 169.370 183.484 194.624 1.00 63.33  ? 406 VAL A CA  1 
ATOM   2638 C C   . VAL A 1 406 ? 168.598 182.350 193.957 1.00 63.33  ? 406 VAL A C   1 
ATOM   2639 O O   . VAL A 1 406 ? 167.613 181.843 194.511 1.00 63.33  ? 406 VAL A O   1 
ATOM   2640 C CB  . VAL A 1 406 ? 168.993 184.855 194.033 1.00 63.33  ? 406 VAL A CB  1 
ATOM   2641 C CG1 . VAL A 1 406 ? 167.514 184.908 193.712 1.00 63.33  ? 406 VAL A CG1 1 
ATOM   2642 C CG2 . VAL A 1 406 ? 169.355 185.962 195.005 1.00 63.33  ? 406 VAL A CG2 1 
ATOM   2643 N N   . VAL A 1 407 ? 169.027 181.931 192.763 1.00 62.31  ? 407 VAL A N   1 
ATOM   2644 C CA  . VAL A 1 407 ? 168.323 180.856 192.066 1.00 62.31  ? 407 VAL A CA  1 
ATOM   2645 C C   . VAL A 1 407 ? 168.402 179.557 192.861 1.00 62.31  ? 407 VAL A C   1 
ATOM   2646 O O   . VAL A 1 407 ? 167.399 178.847 193.022 1.00 62.31  ? 407 VAL A O   1 
ATOM   2647 C CB  . VAL A 1 407 ? 168.881 180.686 190.641 1.00 62.31  ? 407 VAL A CB  1 
ATOM   2648 C CG1 . VAL A 1 407 ? 168.283 179.459 189.981 1.00 62.31  ? 407 VAL A CG1 1 
ATOM   2649 C CG2 . VAL A 1 407 ? 168.593 181.923 189.813 1.00 62.31  ? 407 VAL A CG2 1 
ATOM   2650 N N   . GLY A 1 408 ? 169.588 179.227 193.377 1.00 61.85  ? 408 GLY A N   1 
ATOM   2651 C CA  . GLY A 1 408 ? 169.727 178.020 194.171 1.00 61.85  ? 408 GLY A CA  1 
ATOM   2652 C C   . GLY A 1 408 ? 168.934 178.074 195.461 1.00 61.85  ? 408 GLY A C   1 
ATOM   2653 O O   . GLY A 1 408 ? 168.376 177.068 195.896 1.00 61.85  ? 408 GLY A O   1 
ATOM   2654 N N   . GLY A 1 409 ? 168.877 179.247 196.093 1.00 59.99  ? 409 GLY A N   1 
ATOM   2655 C CA  . GLY A 1 409 ? 168.072 179.388 197.291 1.00 59.99  ? 409 GLY A CA  1 
ATOM   2656 C C   . GLY A 1 409 ? 166.595 179.188 197.021 1.00 59.99  ? 409 GLY A C   1 
ATOM   2657 O O   . GLY A 1 409 ? 165.900 178.523 197.792 1.00 59.99  ? 409 GLY A O   1 
ATOM   2658 N N   . ILE A 1 410 ? 166.098 179.752 195.918 1.00 59.74  ? 410 ILE A N   1 
ATOM   2659 C CA  . ILE A 1 410 ? 164.699 179.547 195.553 1.00 59.74  ? 410 ILE A CA  1 
ATOM   2660 C C   . ILE A 1 410 ? 164.429 178.071 195.294 1.00 59.74  ? 410 ILE A C   1 
ATOM   2661 O O   . ILE A 1 410 ? 163.426 177.516 195.761 1.00 59.74  ? 410 ILE A O   1 
ATOM   2662 C CB  . ILE A 1 410 ? 164.327 180.416 194.337 1.00 59.74  ? 410 ILE A CB  1 
ATOM   2663 C CG1 . ILE A 1 410 ? 164.213 181.883 194.746 1.00 59.74  ? 410 ILE A CG1 1 
ATOM   2664 C CG2 . ILE A 1 410 ? 163.025 179.945 193.721 1.00 59.74  ? 410 ILE A CG2 1 
ATOM   2665 C CD1 . ILE A 1 410 ? 163.915 182.808 193.596 1.00 59.74  ? 410 ILE A CD1 1 
ATOM   2666 N N   . GLY A 1 411 ? 165.325 177.407 194.561 1.00 60.49  ? 411 GLY A N   1 
ATOM   2667 C CA  . GLY A 1 411 ? 165.138 175.989 194.293 1.00 60.49  ? 411 GLY A CA  1 
ATOM   2668 C C   . GLY A 1 411 ? 165.146 175.142 195.553 1.00 60.49  ? 411 GLY A C   1 
ATOM   2669 O O   . GLY A 1 411 ? 164.300 174.261 195.727 1.00 60.49  ? 411 GLY A O   1 
ATOM   2670 N N   . ILE A 1 412 ? 166.097 175.402 196.452 1.00 59.53  ? 412 ILE A N   1 
ATOM   2671 C CA  . ILE A 1 412 ? 166.185 174.639 197.693 1.00 59.53  ? 412 ILE A CA  1 
ATOM   2672 C C   . ILE A 1 412 ? 164.951 174.873 198.553 1.00 59.53  ? 412 ILE A C   1 
ATOM   2673 O O   . ILE A 1 412 ? 164.392 173.933 199.130 1.00 59.53  ? 412 ILE A O   1 
ATOM   2674 C CB  . ILE A 1 412 ? 167.477 174.995 198.450 1.00 59.53  ? 412 ILE A CB  1 
ATOM   2675 C CG1 . ILE A 1 412 ? 168.696 174.437 197.720 1.00 59.53  ? 412 ILE A CG1 1 
ATOM   2676 C CG2 . ILE A 1 412 ? 167.431 174.462 199.868 1.00 59.53  ? 412 ILE A CG2 1 
ATOM   2677 C CD1 . ILE A 1 412 ? 169.984 175.132 198.080 1.00 59.53  ? 412 ILE A CD1 1 
ATOM   2678 N N   . GLY A 1 413 ? 164.510 176.127 198.663 1.00 58.90  ? 413 GLY A N   1 
ATOM   2679 C CA  . GLY A 1 413 ? 163.318 176.408 199.442 1.00 58.90  ? 413 GLY A CA  1 
ATOM   2680 C C   . GLY A 1 413 ? 162.083 175.741 198.873 1.00 58.90  ? 413 GLY A C   1 
ATOM   2681 O O   . GLY A 1 413 ? 161.228 175.258 199.617 1.00 58.90  ? 413 GLY A O   1 
ATOM   2682 N N   . MET A 1 414 ? 161.974 175.701 197.545 1.00 62.41  ? 414 MET A N   1 
ATOM   2683 C CA  . MET A 1 414 ? 160.817 175.068 196.925 1.00 62.41  ? 414 MET A CA  1 
ATOM   2684 C C   . MET A 1 414 ? 160.865 173.552 197.080 1.00 62.41  ? 414 MET A C   1 
ATOM   2685 O O   . MET A 1 414 ? 159.820 172.898 197.162 1.00 62.41  ? 414 MET A O   1 
ATOM   2686 C CB  . MET A 1 414 ? 160.741 175.473 195.453 1.00 62.41  ? 414 MET A CB  1 
ATOM   2687 C CG  . MET A 1 414 ? 159.533 174.948 194.706 1.00 62.41  ? 414 MET A CG  1 
ATOM   2688 S SD  . MET A 1 414 ? 159.489 175.557 193.013 1.00 62.41  ? 414 MET A SD  1 
ATOM   2689 C CE  . MET A 1 414 ? 158.052 174.698 192.384 1.00 62.41  ? 414 MET A CE  1 
ATOM   2690 N N   . ALA A 1 415 ? 162.069 172.974 197.131 1.00 59.76  ? 415 ALA A N   1 
ATOM   2691 C CA  . ALA A 1 415 ? 162.190 171.523 197.228 1.00 59.76  ? 415 ALA A CA  1 
ATOM   2692 C C   . ALA A 1 415 ? 162.099 171.006 198.661 1.00 59.76  ? 415 ALA A C   1 
ATOM   2693 O O   . ALA A 1 415 ? 161.700 169.856 198.868 1.00 59.76  ? 415 ALA A O   1 
ATOM   2694 C CB  . ALA A 1 415 ? 163.507 171.064 196.603 1.00 59.76  ? 415 ALA A CB  1 
ATOM   2695 N N   . VAL A 1 416 ? 162.466 171.818 199.656 1.00 59.57  ? 416 VAL A N   1 
ATOM   2696 C CA  . VAL A 1 416 ? 162.569 171.311 201.024 1.00 59.57  ? 416 VAL A CA  1 
ATOM   2697 C C   . VAL A 1 416 ? 161.195 171.000 201.609 1.00 59.57  ? 416 VAL A C   1 
ATOM   2698 O O   . VAL A 1 416 ? 161.012 169.967 202.263 1.00 59.57  ? 416 VAL A O   1 
ATOM   2699 C CB  . VAL A 1 416 ? 163.350 172.304 201.906 1.00 59.57  ? 416 VAL A CB  1 
ATOM   2700 C CG1 . VAL A 1 416 ? 163.071 172.047 203.372 1.00 59.57  ? 416 VAL A CG1 1 
ATOM   2701 C CG2 . VAL A 1 416 ? 164.836 172.173 201.649 1.00 59.57  ? 416 VAL A CG2 1 
ATOM   2702 N N   . VAL A 1 417 ? 160.212 171.879 201.393 1.00 58.36  ? 417 VAL A N   1 
ATOM   2703 C CA  . VAL A 1 417 ? 158.921 171.729 202.072 1.00 58.36  ? 417 VAL A CA  1 
ATOM   2704 C C   . VAL A 1 417 ? 158.233 170.405 201.754 1.00 58.36  ? 417 VAL A C   1 
ATOM   2705 O O   . VAL A 1 417 ? 157.814 169.713 202.696 1.00 58.36  ? 417 VAL A O   1 
ATOM   2706 C CB  . VAL A 1 417 ? 158.023 172.945 201.780 1.00 58.36  ? 417 VAL A CB  1 
ATOM   2707 C CG1 . VAL A 1 417 ? 156.610 172.687 202.270 1.00 58.36  ? 417 VAL A CG1 1 
ATOM   2708 C CG2 . VAL A 1 417 ? 158.578 174.179 202.445 1.00 58.36  ? 417 VAL A CG2 1 
ATOM   2709 N N   . PRO A 1 418 ? 158.066 169.997 200.489 1.00 59.13  ? 418 PRO A N   1 
ATOM   2710 C CA  . PRO A 1 418 ? 157.414 168.699 200.242 1.00 59.13  ? 418 PRO A CA  1 
ATOM   2711 C C   . PRO A 1 418 ? 158.176 167.510 200.803 1.00 59.13  ? 418 PRO A C   1 
ATOM   2712 O O   . PRO A 1 418 ? 157.548 166.544 201.255 1.00 59.13  ? 418 PRO A O   1 
ATOM   2713 C CB  . PRO A 1 418 ? 157.320 168.641 198.711 1.00 59.13  ? 418 PRO A CB  1 
ATOM   2714 C CG  . PRO A 1 418 ? 158.353 169.579 198.229 1.00 59.13  ? 418 PRO A CG  1 
ATOM   2715 C CD  . PRO A 1 418 ? 158.377 170.684 199.223 1.00 59.13  ? 418 PRO A CD  1 
ATOM   2716 N N   . LEU A 1 419 ? 159.511 167.550 200.794 1.00 58.94  ? 419 LEU A N   1 
ATOM   2717 C CA  . LEU A 1 419 ? 160.289 166.415 201.281 1.00 58.94  ? 419 LEU A CA  1 
ATOM   2718 C C   . LEU A 1 419 ? 160.072 166.186 202.770 1.00 58.94  ? 419 LEU A C   1 
ATOM   2719 O O   . LEU A 1 419 ? 159.893 165.046 203.211 1.00 58.94  ? 419 LEU A O   1 
ATOM   2720 C CB  . LEU A 1 419 ? 161.772 166.628 200.985 1.00 58.94  ? 419 LEU A CB  1 
ATOM   2721 C CG  . LEU A 1 419 ? 162.317 165.990 199.708 1.00 58.94  ? 419 LEU A CG  1 
ATOM   2722 C CD1 . LEU A 1 419 ? 163.772 166.368 199.503 1.00 58.94  ? 419 LEU A CD1 1 
ATOM   2723 C CD2 . LEU A 1 419 ? 162.156 164.483 199.759 1.00 58.94  ? 419 LEU A CD2 1 
ATOM   2724 N N   . THR A 1 420 ? 160.091 167.254 203.563 1.00 60.44  ? 420 THR A N   1 
ATOM   2725 C CA  . THR A 1 420 ? 159.863 167.132 204.996 1.00 60.44  ? 420 THR A CA  1 
ATOM   2726 C C   . THR A 1 420 ? 158.387 167.100 205.366 1.00 60.44  ? 420 THR A C   1 
ATOM   2727 O O   . THR A 1 420 ? 158.064 166.784 206.515 1.00 60.44  ? 420 THR A O   1 
ATOM   2728 C CB  . THR A 1 420 ? 160.573 168.268 205.738 1.00 60.44  ? 420 THR A CB  1 
ATOM   2729 O OG1 . THR A 1 420 ? 160.389 168.114 207.150 1.00 60.44  ? 420 THR A OG1 1 
ATOM   2730 C CG2 . THR A 1 420 ? 160.054 169.602 205.291 1.00 60.44  ? 420 THR A CG2 1 
ATOM   2731 N N   . LEU A 1 421 ? 157.488 167.422 204.436 1.00 58.83  ? 421 LEU A N   1 
ATOM   2732 C CA  . LEU A 1 421 ? 156.075 167.135 204.646 1.00 58.83  ? 421 LEU A CA  1 
ATOM   2733 C C   . LEU A 1 421 ? 155.767 165.662 204.429 1.00 58.83  ? 421 LEU A C   1 
ATOM   2734 O O   . LEU A 1 421 ? 154.877 165.115 205.087 1.00 58.83  ? 421 LEU A O   1 
ATOM   2735 C CB  . LEU A 1 421 ? 155.212 167.986 203.713 1.00 58.83  ? 421 LEU A CB  1 
ATOM   2736 C CG  . LEU A 1 421 ? 154.587 169.257 204.285 1.00 58.83  ? 421 LEU A CG  1 
ATOM   2737 C CD1 . LEU A 1 421 ? 153.846 170.007 203.198 1.00 58.83  ? 421 LEU A CD1 1 
ATOM   2738 C CD2 . LEU A 1 421 ? 153.658 168.923 205.430 1.00 58.83  ? 421 LEU A CD2 1 
ATOM   2739 N N   . SER A 1 422 ? 156.486 165.013 203.511 1.00 61.18  ? 422 SER A N   1 
ATOM   2740 C CA  . SER A 1 422 ? 156.273 163.601 203.228 1.00 61.18  ? 422 SER A CA  1 
ATOM   2741 C C   . SER A 1 422 ? 156.917 162.684 204.259 1.00 61.18  ? 422 SER A C   1 
ATOM   2742 O O   . SER A 1 422 ? 156.576 161.498 204.310 1.00 61.18  ? 422 SER A O   1 
ATOM   2743 C CB  . SER A 1 422 ? 156.818 163.260 201.841 1.00 61.18  ? 422 SER A CB  1 
ATOM   2744 O OG  . SER A 1 422 ? 156.142 163.988 200.833 1.00 61.18  ? 422 SER A OG  1 
ATOM   2745 N N   . ALA A 1 423 ? 157.834 163.198 205.076 1.00 61.30  ? 423 ALA A N   1 
ATOM   2746 C CA  . ALA A 1 423 ? 158.541 162.371 206.045 1.00 61.30  ? 423 ALA A CA  1 
ATOM   2747 C C   . ALA A 1 423 ? 157.737 162.106 207.309 1.00 61.30  ? 423 ALA A C   1 
ATOM   2748 O O   . ALA A 1 423 ? 158.101 161.209 208.076 1.00 61.30  ? 423 ALA A O   1 
ATOM   2749 C CB  . ALA A 1 423 ? 159.872 163.025 206.419 1.00 61.30  ? 423 ALA A CB  1 
ATOM   2750 N N   . ILE A 1 424 ? 156.662 162.854 207.546 1.00 63.29  ? 424 ILE A N   1 
ATOM   2751 C CA  . ILE A 1 424 ? 155.878 162.721 208.768 1.00 63.29  ? 424 ILE A CA  1 
ATOM   2752 C C   . ILE A 1 424 ? 154.427 162.420 208.422 1.00 63.29  ? 424 ILE A C   1 
ATOM   2753 O O   . ILE A 1 424 ? 153.511 162.783 209.168 1.00 63.29  ? 424 ILE A O   1 
ATOM   2754 C CB  . ILE A 1 424 ? 155.994 163.990 209.632 1.00 63.29  ? 424 ILE A CB  1 
ATOM   2755 C CG1 . ILE A 1 424 ? 155.553 165.218 208.835 1.00 63.29  ? 424 ILE A CG1 1 
ATOM   2756 C CG2 . ILE A 1 424 ? 157.415 164.161 210.139 1.00 63.29  ? 424 ILE A CG2 1 
ATOM   2757 C CD1 . ILE A 1 424 ? 155.458 166.477 209.659 1.00 63.29  ? 424 ILE A CD1 1 
ATOM   2758 N N   . ALA A 1 425 ? 154.208 161.743 207.300 1.00 67.96  ? 425 ALA A N   1 
ATOM   2759 C CA  . ALA A 1 425 ? 152.871 161.491 206.783 1.00 67.96  ? 425 ALA A CA  1 
ATOM   2760 C C   . ALA A 1 425 ? 152.396 160.100 207.183 1.00 67.96  ? 425 ALA A C   1 
ATOM   2761 O O   . ALA A 1 425 ? 153.094 159.109 206.948 1.00 67.96  ? 425 ALA A O   1 
ATOM   2762 C CB  . ALA A 1 425 ? 152.847 161.634 205.261 1.00 67.96  ? 425 ALA A CB  1 
ATOM   2763 N N   . GLY A 1 426 ? 151.207 160.034 207.780 1.00 72.42  ? 426 GLY A N   1 
ATOM   2764 C CA  . GLY A 1 426 ? 150.559 158.771 208.076 1.00 72.42  ? 426 GLY A CA  1 
ATOM   2765 C C   . GLY A 1 426 ? 151.283 157.864 209.051 1.00 72.42  ? 426 GLY A C   1 
ATOM   2766 O O   . GLY A 1 426 ? 151.447 156.671 208.780 1.00 72.42  ? 426 GLY A O   1 
ATOM   2767 N N   . VAL A 1 427 ? 151.722 158.405 210.185 1.00 72.23  ? 427 VAL A N   1 
ATOM   2768 C CA  . VAL A 1 427 ? 152.436 157.635 211.191 1.00 72.23  ? 427 VAL A CA  1 
ATOM   2769 C C   . VAL A 1 427 ? 151.627 157.482 212.474 1.00 72.23  ? 427 VAL A C   1 
ATOM   2770 O O   . VAL A 1 427 ? 151.666 156.425 213.108 1.00 72.23  ? 427 VAL A O   1 
ATOM   2771 C CB  . VAL A 1 427 ? 153.821 158.254 211.481 1.00 72.23  ? 427 VAL A CB  1 
ATOM   2772 C CG1 . VAL A 1 427 ? 154.697 158.179 210.248 1.00 72.23  ? 427 VAL A CG1 1 
ATOM   2773 C CG2 . VAL A 1 427 ? 153.676 159.694 211.926 1.00 72.23  ? 427 VAL A CG2 1 
ATOM   2774 N N   . GLY A 1 428 ? 150.886 158.511 212.872 1.00 73.57  ? 428 GLY A N   1 
ATOM   2775 C CA  . GLY A 1 428 ? 150.148 158.478 214.116 1.00 73.57  ? 428 GLY A CA  1 
ATOM   2776 C C   . GLY A 1 428 ? 150.940 159.050 215.278 1.00 73.57  ? 428 GLY A C   1 
ATOM   2777 O O   . GLY A 1 428 ? 152.113 159.414 215.165 1.00 73.57  ? 428 GLY A O   1 
ATOM   2778 N N   . PHE A 1 429 ? 150.271 159.132 216.429 1.00 76.01  ? 429 PHE A N   1 
ATOM   2779 C CA  . PHE A 1 429 ? 150.886 159.745 217.601 1.00 76.01  ? 429 PHE A CA  1 
ATOM   2780 C C   . PHE A 1 429 ? 151.903 158.835 218.277 1.00 76.01  ? 429 PHE A C   1 
ATOM   2781 O O   . PHE A 1 429 ? 152.895 159.326 218.825 1.00 76.01  ? 429 PHE A O   1 
ATOM   2782 C CB  . PHE A 1 429 ? 149.812 160.152 218.610 1.00 76.01  ? 429 PHE A CB  1 
ATOM   2783 C CG  . PHE A 1 429 ? 149.340 161.567 218.454 1.00 76.01  ? 429 PHE A CG  1 
ATOM   2784 C CD1 . PHE A 1 429 ? 149.028 162.074 217.205 1.00 76.01  ? 429 PHE A CD1 1 
ATOM   2785 C CD2 . PHE A 1 429 ? 149.209 162.392 219.557 1.00 76.01  ? 429 PHE A CD2 1 
ATOM   2786 C CE1 . PHE A 1 429 ? 148.592 163.376 217.059 1.00 76.01  ? 429 PHE A CE1 1 
ATOM   2787 C CE2 . PHE A 1 429 ? 148.773 163.695 219.418 1.00 76.01  ? 429 PHE A CE2 1 
ATOM   2788 C CZ  . PHE A 1 429 ? 148.465 164.187 218.167 1.00 76.01  ? 429 PHE A CZ  1 
ATOM   2789 N N   . ASP A 1 430 ? 151.681 157.522 218.258 1.00 76.56  ? 430 ASP A N   1 
ATOM   2790 C CA  . ASP A 1 430 ? 152.539 156.609 219.000 1.00 76.56  ? 430 ASP A CA  1 
ATOM   2791 C C   . ASP A 1 430 ? 153.829 156.262 218.271 1.00 76.56  ? 430 ASP A C   1 
ATOM   2792 O O   . ASP A 1 430 ? 154.685 155.592 218.856 1.00 76.56  ? 430 ASP A O   1 
ATOM   2793 C CB  . ASP A 1 430 ? 151.780 155.323 219.330 1.00 76.56  ? 430 ASP A CB  1 
ATOM   2794 C CG  . ASP A 1 430 ? 151.189 154.663 218.102 1.00 76.56  ? 430 ASP A CG  1 
ATOM   2795 O OD1 . ASP A 1 430 ? 151.285 155.248 217.003 1.00 76.56  ? 430 ASP A OD1 1 
ATOM   2796 O OD2 . ASP A 1 430 ? 150.624 153.557 218.235 1.00 76.56  ? 430 ASP A OD2 1 
ATOM   2797 N N   . GLN A 1 431 ? 153.993 156.690 217.018 1.00 72.95  ? 431 GLN A N   1 
ATOM   2798 C CA  . GLN A 1 431 ? 155.186 156.360 216.250 1.00 72.95  ? 431 GLN A CA  1 
ATOM   2799 C C   . GLN A 1 431 ? 155.828 157.578 215.596 1.00 72.95  ? 431 GLN A C   1 
ATOM   2800 O O   . GLN A 1 431 ? 156.770 157.417 214.814 1.00 72.95  ? 431 GLN A O   1 
ATOM   2801 C CB  . GLN A 1 431 ? 154.860 155.312 215.181 1.00 72.95  ? 431 GLN A CB  1 
ATOM   2802 C CG  . GLN A 1 431 ? 154.149 154.084 215.722 1.00 72.95  ? 431 GLN A CG  1 
ATOM   2803 C CD  . GLN A 1 431 ? 154.248 152.892 214.796 1.00 72.95  ? 431 GLN A CD  1 
ATOM   2804 O OE1 . GLN A 1 431 ? 153.785 152.938 213.658 1.00 72.95  ? 431 GLN A OE1 1 
ATOM   2805 N NE2 . GLN A 1 431 ? 154.851 151.814 215.281 1.00 72.95  ? 431 GLN A NE2 1 
ATOM   2806 N N   . ILE A 1 432 ? 155.348 158.787 215.894 1.00 66.53  ? 432 ILE A N   1 
ATOM   2807 C CA  . ILE A 1 432 ? 155.916 159.982 215.278 1.00 66.53  ? 432 ILE A CA  1 
ATOM   2808 C C   . ILE A 1 432 ? 157.309 160.275 215.826 1.00 66.53  ? 432 ILE A C   1 
ATOM   2809 O O   . ILE A 1 432 ? 158.179 160.765 215.095 1.00 66.53  ? 432 ILE A O   1 
ATOM   2810 C CB  . ILE A 1 432 ? 154.961 161.177 215.460 1.00 66.53  ? 432 ILE A CB  1 
ATOM   2811 C CG1 . ILE A 1 432 ? 155.537 162.439 214.815 1.00 66.53  ? 432 ILE A CG1 1 
ATOM   2812 C CG2 . ILE A 1 432 ? 154.661 161.412 216.928 1.00 66.53  ? 432 ILE A CG2 1 
ATOM   2813 C CD1 . ILE A 1 432 ? 155.834 162.293 213.344 1.00 66.53  ? 432 ILE A CD1 1 
ATOM   2814 N N   . GLY A 1 433 ? 157.550 159.984 217.103 1.00 66.62  ? 433 GLY A N   1 
ATOM   2815 C CA  . GLY A 1 433 ? 158.808 160.295 217.741 1.00 66.62  ? 433 GLY A CA  1 
ATOM   2816 C C   . GLY A 1 433 ? 160.011 159.615 217.115 1.00 66.62  ? 433 GLY A C   1 
ATOM   2817 O O   . GLY A 1 433 ? 160.969 160.270 216.684 1.00 66.62  ? 433 GLY A O   1 
ATOM   2818 N N   . PRO A 1 434 ? 160.002 158.279 217.084 1.00 65.22  ? 434 PRO A N   1 
ATOM   2819 C CA  . PRO A 1 434 ? 161.096 157.565 216.411 1.00 65.22  ? 434 PRO A CA  1 
ATOM   2820 C C   . PRO A 1 434 ? 161.229 157.900 214.937 1.00 65.22  ? 434 PRO A C   1 
ATOM   2821 O O   . PRO A 1 434 ? 162.353 157.935 214.429 1.00 65.22  ? 434 PRO A O   1 
ATOM   2822 C CB  . PRO A 1 434 ? 160.740 156.087 216.629 1.00 65.22  ? 434 PRO A CB  1 
ATOM   2823 C CG  . PRO A 1 434 ? 159.319 156.079 217.079 1.00 65.22  ? 434 PRO A CG  1 
ATOM   2824 C CD  . PRO A 1 434 ? 159.121 157.356 217.813 1.00 65.22  ? 434 PRO A CD  1 
ATOM   2825 N N   . VAL A 1 435 ? 160.125 158.153 214.231 1.00 62.27  ? 435 VAL A N   1 
ATOM   2826 C CA  . VAL A 1 435 ? 160.219 158.501 212.816 1.00 62.27  ? 435 VAL A CA  1 
ATOM   2827 C C   . VAL A 1 435 ? 160.935 159.834 212.637 1.00 62.27  ? 435 VAL A C   1 
ATOM   2828 O O   . VAL A 1 435 ? 161.804 159.980 211.766 1.00 62.27  ? 435 VAL A O   1 
ATOM   2829 C CB  . VAL A 1 435 ? 158.818 158.515 212.179 1.00 62.27  ? 435 VAL A CB  1 
ATOM   2830 C CG1 . VAL A 1 435 ? 158.844 159.242 210.850 1.00 62.27  ? 435 VAL A CG1 1 
ATOM   2831 C CG2 . VAL A 1 435 ? 158.308 157.099 211.999 1.00 62.27  ? 435 VAL A CG2 1 
ATOM   2832 N N   . SER A 1 436 ? 160.590 160.826 213.460 1.00 59.81  ? 436 SER A N   1 
ATOM   2833 C CA  . SER A 1 436 ? 161.278 162.110 213.406 1.00 59.81  ? 436 SER A CA  1 
ATOM   2834 C C   . SER A 1 436 ? 162.751 161.963 213.770 1.00 59.81  ? 436 SER A C   1 
ATOM   2835 O O   . SER A 1 436 ? 163.621 162.586 213.145 1.00 59.81  ? 436 SER A O   1 
ATOM   2836 C CB  . SER A 1 436 ? 160.591 163.102 214.340 1.00 59.81  ? 436 SER A CB  1 
ATOM   2837 O OG  . SER A 1 436 ? 159.249 163.309 213.944 1.00 59.81  ? 436 SER A OG  1 
ATOM   2838 N N   . ALA A 1 437 ? 163.049 161.145 214.781 1.00 59.46  ? 437 ALA A N   1 
ATOM   2839 C CA  . ALA A 1 437 ? 164.441 160.916 215.153 1.00 59.46  ? 437 ALA A CA  1 
ATOM   2840 C C   . ALA A 1 437 ? 165.222 160.286 214.008 1.00 59.46  ? 437 ALA A C   1 
ATOM   2841 O O   . ALA A 1 437 ? 166.364 160.673 213.738 1.00 59.46  ? 437 ALA A O   1 
ATOM   2842 C CB  . ALA A 1 437 ? 164.515 160.039 216.400 1.00 59.46  ? 437 ALA A CB  1 
ATOM   2843 N N   . ILE A 1 438 ? 164.621 159.315 213.320 1.00 60.64  ? 438 ILE A N   1 
ATOM   2844 C CA  . ILE A 1 438 ? 165.291 158.663 212.200 1.00 60.64  ? 438 ILE A CA  1 
ATOM   2845 C C   . ILE A 1 438 ? 165.519 159.649 211.061 1.00 60.64  ? 438 ILE A C   1 
ATOM   2846 O O   . ILE A 1 438 ? 166.571 159.634 210.416 1.00 60.64  ? 438 ILE A O   1 
ATOM   2847 C CB  . ILE A 1 438 ? 164.489 157.433 211.736 1.00 60.64  ? 438 ILE A CB  1 
ATOM   2848 C CG1 . ILE A 1 438 ? 164.493 156.354 212.816 1.00 60.64  ? 438 ILE A CG1 1 
ATOM   2849 C CG2 . ILE A 1 438 ? 165.073 156.864 210.462 1.00 60.64  ? 438 ILE A CG2 1 
ATOM   2850 C CD1 . ILE A 1 438 ? 163.352 155.375 212.696 1.00 60.64  ? 438 ILE A CD1 1 
ATOM   2851 N N   . ALA A 1 439 ? 164.538 160.512 210.784 1.00 59.49  ? 439 ALA A N   1 
ATOM   2852 C CA  . ALA A 1 439 ? 164.711 161.501 209.722 1.00 59.49  ? 439 ALA A CA  1 
ATOM   2853 C C   . ALA A 1 439 ? 165.853 162.462 210.043 1.00 59.49  ? 439 ALA A C   1 
ATOM   2854 O O   . ALA A 1 439 ? 166.703 162.749 209.187 1.00 59.49  ? 439 ALA A O   1 
ATOM   2855 C CB  . ALA A 1 439 ? 163.407 162.265 209.499 1.00 59.49  ? 439 ALA A CB  1 
ATOM   2856 N N   . LEU A 1 440 ? 165.896 162.959 211.284 1.00 60.69  ? 440 LEU A N   1 
ATOM   2857 C CA  . LEU A 1 440 ? 166.992 163.835 211.691 1.00 60.69  ? 440 LEU A CA  1 
ATOM   2858 C C   . LEU A 1 440 ? 168.335 163.124 211.595 1.00 60.69  ? 440 LEU A C   1 
ATOM   2859 O O   . LEU A 1 440 ? 169.323 163.705 211.126 1.00 60.69  ? 440 LEU A O   1 
ATOM   2860 C CB  . LEU A 1 440 ? 166.768 164.344 213.116 1.00 60.69  ? 440 LEU A CB  1 
ATOM   2861 C CG  . LEU A 1 440 ? 166.026 165.662 213.345 1.00 60.69  ? 440 LEU A CG  1 
ATOM   2862 C CD1 . LEU A 1 440 ? 166.815 166.825 212.776 1.00 60.69  ? 440 LEU A CD1 1 
ATOM   2863 C CD2 . LEU A 1 440 ? 164.634 165.623 212.754 1.00 60.69  ? 440 LEU A CD2 1 
ATOM   2864 N N   . MET A 1 441 ? 168.395 161.867 212.040 1.00 62.36  ? 441 MET A N   1 
ATOM   2865 C CA  . MET A 1 441 ? 169.650 161.127 211.992 1.00 62.36  ? 441 MET A CA  1 
ATOM   2866 C C   . MET A 1 441 ? 170.108 160.891 210.561 1.00 62.36  ? 441 MET A C   1 
ATOM   2867 O O   . MET A 1 441 ? 171.302 160.985 210.271 1.00 62.36  ? 441 MET A O   1 
ATOM   2868 C CB  . MET A 1 441 ? 169.515 159.800 212.733 1.00 62.36  ? 441 MET A CB  1 
ATOM   2869 C CG  . MET A 1 441 ? 170.820 159.034 212.819 1.00 62.36  ? 441 MET A CG  1 
ATOM   2870 S SD  . MET A 1 441 ? 170.665 157.480 213.704 1.00 62.36  ? 441 MET A SD  1 
ATOM   2871 C CE  . MET A 1 441 ? 170.473 158.092 215.371 1.00 62.36  ? 441 MET A CE  1 
ATOM   2872 N N   . LEU A 1 442 ? 169.183 160.568 209.657 1.00 59.26  ? 442 LEU A N   1 
ATOM   2873 C CA  . LEU A 1 442 ? 169.562 160.359 208.264 1.00 59.26  ? 442 LEU A CA  1 
ATOM   2874 C C   . LEU A 1 442 ? 170.079 161.646 207.638 1.00 59.26  ? 442 LEU A C   1 
ATOM   2875 O O   . LEU A 1 442 ? 171.082 161.633 206.912 1.00 59.26  ? 442 LEU A O   1 
ATOM   2876 C CB  . LEU A 1 442 ? 168.377 159.812 207.470 1.00 59.26  ? 442 LEU A CB  1 
ATOM   2877 C CG  . LEU A 1 442 ? 168.032 158.340 207.694 1.00 59.26  ? 442 LEU A CG  1 
ATOM   2878 C CD1 . LEU A 1 442 ? 167.099 157.850 206.610 1.00 59.26  ? 442 LEU A CD1 1 
ATOM   2879 C CD2 . LEU A 1 442 ? 169.286 157.488 207.743 1.00 59.26  ? 442 LEU A CD2 1 
ATOM   2880 N N   . GLN A 1 443 ? 169.415 162.771 207.915 1.00 63.30  ? 443 GLN A N   1 
ATOM   2881 C CA  . GLN A 1 443 ? 169.917 164.047 207.415 1.00 63.30  ? 443 GLN A CA  1 
ATOM   2882 C C   . GLN A 1 443 ? 171.316 164.338 207.939 1.00 63.30  ? 443 GLN A C   1 
ATOM   2883 O O   . GLN A 1 443 ? 172.199 164.746 207.177 1.00 63.30  ? 443 GLN A O   1 
ATOM   2884 C CB  . GLN A 1 443 ? 168.982 165.184 207.809 1.00 63.30  ? 443 GLN A CB  1 
ATOM   2885 C CG  . GLN A 1 443 ? 169.415 166.515 207.240 1.00 63.30  ? 443 GLN A CG  1 
ATOM   2886 C CD  . GLN A 1 443 ? 168.465 167.625 207.590 1.00 63.30  ? 443 GLN A CD  1 
ATOM   2887 O OE1 . GLN A 1 443 ? 167.488 167.412 208.297 1.00 63.30  ? 443 GLN A OE1 1 
ATOM   2888 N NE2 . GLN A 1 443 ? 168.750 168.825 207.103 1.00 63.30  ? 443 GLN A NE2 1 
ATOM   2889 N N   . SER A 1 444 ? 171.536 164.140 209.240 1.00 61.10  ? 444 SER A N   1 
ATOM   2890 C CA  . SER A 1 444 ? 172.837 164.453 209.821 1.00 61.10  ? 444 SER A CA  1 
ATOM   2891 C C   . SER A 1 444 ? 173.916 163.490 209.344 1.00 61.10  ? 444 SER A C   1 
ATOM   2892 O O   . SER A 1 444 ? 175.085 163.873 209.240 1.00 61.10  ? 444 SER A O   1 
ATOM   2893 C CB  . SER A 1 444 ? 172.744 164.436 211.344 1.00 61.10  ? 444 SER A CB  1 
ATOM   2894 O OG  . SER A 1 444 ? 171.779 165.367 211.800 1.00 61.10  ? 444 SER A OG  1 
ATOM   2895 N N   . LEU A 1 445 ? 173.546 162.244 209.058 1.00 60.19  ? 445 LEU A N   1 
ATOM   2896 C CA  . LEU A 1 445 ? 174.497 161.234 208.615 1.00 60.19  ? 445 LEU A CA  1 
ATOM   2897 C C   . LEU A 1 445 ? 174.885 161.407 207.154 1.00 60.19  ? 445 LEU A C   1 
ATOM   2898 O O   . LEU A 1 445 ? 176.027 161.113 206.786 1.00 60.19  ? 445 LEU A O   1 
ATOM   2899 C CB  . LEU A 1 445 ? 173.901 159.844 208.851 1.00 60.19  ? 445 LEU A CB  1 
ATOM   2900 C CG  . LEU A 1 445 ? 174.717 158.570 208.640 1.00 60.19  ? 445 LEU A CG  1 
ATOM   2901 C CD1 . LEU A 1 445 ? 174.209 157.493 209.573 1.00 60.19  ? 445 LEU A CD1 1 
ATOM   2902 C CD2 . LEU A 1 445 ? 174.608 158.093 207.206 1.00 60.19  ? 445 LEU A CD2 1 
ATOM   2903 N N   . GLY A 1 446 ? 173.963 161.874 206.310 1.00 62.26  ? 446 GLY A N   1 
ATOM   2904 C CA  . GLY A 1 446 ? 174.252 161.959 204.889 1.00 62.26  ? 446 GLY A CA  1 
ATOM   2905 C C   . GLY A 1 446 ? 175.328 162.959 204.520 1.00 62.26  ? 446 GLY A C   1 
ATOM   2906 O O   . GLY A 1 446 ? 175.982 162.790 203.488 1.00 62.26  ? 446 GLY A O   1 
ATOM   2907 N N   . GLY A 1 447 ? 175.533 163.986 205.340 1.00 61.83  ? 447 GLY A N   1 
ATOM   2908 C CA  . GLY A 1 447 ? 176.440 165.065 205.019 1.00 61.83  ? 447 GLY A CA  1 
ATOM   2909 C C   . GLY A 1 447 ? 177.894 164.657 204.870 1.00 61.83  ? 447 GLY A C   1 
ATOM   2910 O O   . GLY A 1 447 ? 178.488 164.775 203.790 1.00 61.83  ? 447 GLY A O   1 
ATOM   2911 N N   . PRO A 1 448 ? 178.504 164.192 205.965 1.00 62.32  ? 448 PRO A N   1 
ATOM   2912 C CA  . PRO A 1 448 ? 179.927 163.817 205.907 1.00 62.32  ? 448 PRO A CA  1 
ATOM   2913 C C   . PRO A 1 448 ? 180.246 162.762 204.864 1.00 62.32  ? 448 PRO A C   1 
ATOM   2914 O O   . PRO A 1 448 ? 181.344 162.789 204.293 1.00 62.32  ? 448 PRO A O   1 
ATOM   2915 C CB  . PRO A 1 448 ? 180.214 163.305 207.324 1.00 62.32  ? 448 PRO A CB  1 
ATOM   2916 C CG  . PRO A 1 448 ? 179.178 163.915 208.184 1.00 62.32  ? 448 PRO A CG  1 
ATOM   2917 C CD  . PRO A 1 448 ? 177.992 164.255 207.344 1.00 62.32  ? 448 PRO A CD  1 
ATOM   2918 N N   . LEU A 1 449 ? 179.323 161.838 204.591 1.00 62.20  ? 449 LEU A N   1 
ATOM   2919 C CA  . LEU A 1 449 ? 179.581 160.800 203.597 1.00 62.20  ? 449 LEU A CA  1 
ATOM   2920 C C   . LEU A 1 449 ? 179.868 161.404 202.228 1.00 62.20  ? 449 LEU A C   1 
ATOM   2921 O O   . LEU A 1 449 ? 180.854 161.048 201.573 1.00 62.20  ? 449 LEU A O   1 
ATOM   2922 C CB  . LEU A 1 449 ? 178.392 159.842 203.519 1.00 62.20  ? 449 LEU A CB  1 
ATOM   2923 C CG  . LEU A 1 449 ? 178.064 159.016 204.762 1.00 62.20  ? 449 LEU A CG  1 
ATOM   2924 C CD1 . LEU A 1 449 ? 177.070 157.924 204.415 1.00 62.20  ? 449 LEU A CD1 1 
ATOM   2925 C CD2 . LEU A 1 449 ? 179.323 158.423 205.369 1.00 62.20  ? 449 LEU A CD2 1 
ATOM   2926 N N   . VAL A 1 450 ? 179.013 162.321 201.776 1.00 60.51  ? 450 VAL A N   1 
ATOM   2927 C CA  . VAL A 1 450 ? 179.222 162.955 200.478 1.00 60.51  ? 450 VAL A CA  1 
ATOM   2928 C C   . VAL A 1 450 ? 180.383 163.939 200.542 1.00 60.51  ? 450 VAL A C   1 
ATOM   2929 O O   . VAL A 1 450 ? 181.136 164.100 199.569 1.00 60.51  ? 450 VAL A O   1 
ATOM   2930 C CB  . VAL A 1 450 ? 177.924 163.633 200.005 1.00 60.51  ? 450 VAL A CB  1 
ATOM   2931 C CG1 . VAL A 1 450 ? 178.058 164.099 198.567 1.00 60.51  ? 450 VAL A CG1 1 
ATOM   2932 C CG2 . VAL A 1 450 ? 176.750 162.681 200.147 1.00 60.51  ? 450 VAL A CG2 1 
ATOM   2933 N N   . LEU A 1 451 ? 180.541 164.620 201.680 1.00 60.27  ? 451 LEU A N   1 
ATOM   2934 C CA  . LEU A 1 451 ? 181.608 165.607 201.802 1.00 60.27  ? 451 LEU A CA  1 
ATOM   2935 C C   . LEU A 1 451 ? 182.980 164.961 201.670 1.00 60.27  ? 451 LEU A C   1 
ATOM   2936 O O   . LEU A 1 451 ? 183.896 165.554 201.092 1.00 60.27  ? 451 LEU A O   1 
ATOM   2937 C CB  . LEU A 1 451 ? 181.491 166.350 203.131 1.00 60.27  ? 451 LEU A CB  1 
ATOM   2938 C CG  . LEU A 1 451 ? 182.406 167.564 203.280 1.00 60.27  ? 451 LEU A CG  1 
ATOM   2939 C CD1 . LEU A 1 451 ? 182.259 168.491 202.089 1.00 60.27  ? 451 LEU A CD1 1 
ATOM   2940 C CD2 . LEU A 1 451 ? 182.113 168.299 204.570 1.00 60.27  ? 451 LEU A CD2 1 
ATOM   2941 N N   . ALA A 1 452 ? 183.144 163.748 202.206 1.00 61.28  ? 452 ALA A N   1 
ATOM   2942 C CA  . ALA A 1 452 ? 184.425 163.059 202.085 1.00 61.28  ? 452 ALA A CA  1 
ATOM   2943 C C   . ALA A 1 452 ? 184.779 162.799 200.626 1.00 61.28  ? 452 ALA A C   1 
ATOM   2944 O O   . ALA A 1 452 ? 185.916 163.037 200.204 1.00 61.28  ? 452 ALA A O   1 
ATOM   2945 C CB  . ALA A 1 452 ? 184.391 161.749 202.870 1.00 61.28  ? 452 ALA A CB  1 
ATOM   2946 N N   . VAL A 1 453 ? 183.812 162.325 199.837 1.00 60.83  ? 453 VAL A N   1 
ATOM   2947 C CA  . VAL A 1 453 ? 184.056 162.066 198.421 1.00 60.83  ? 453 VAL A CA  1 
ATOM   2948 C C   . VAL A 1 453 ? 184.393 163.359 197.690 1.00 60.83  ? 453 VAL A C   1 
ATOM   2949 O O   . VAL A 1 453 ? 185.329 163.408 196.878 1.00 60.83  ? 453 VAL A O   1 
ATOM   2950 C CB  . VAL A 1 453 ? 182.837 161.366 197.792 1.00 60.83  ? 453 VAL A CB  1 
ATOM   2951 C CG1 . VAL A 1 453 ? 183.144 160.942 196.369 1.00 60.83  ? 453 VAL A CG1 1 
ATOM   2952 C CG2 . VAL A 1 453 ? 182.420 160.172 198.630 1.00 60.83  ? 453 VAL A CG2 1 
ATOM   2953 N N   . ILE A 1 454 ? 183.634 164.425 197.959 1.00 59.50  ? 454 ILE A N   1 
ATOM   2954 C CA  . ILE A 1 454 ? 183.871 165.686 197.261 1.00 59.50  ? 454 ILE A CA  1 
ATOM   2955 C C   . ILE A 1 454 ? 185.256 166.231 197.594 1.00 59.50  ? 454 ILE A C   1 
ATOM   2956 O O   . ILE A 1 454 ? 185.986 166.697 196.709 1.00 59.50  ? 454 ILE A O   1 
ATOM   2957 C CB  . ILE A 1 454 ? 182.764 166.703 197.592 1.00 59.50  ? 454 ILE A CB  1 
ATOM   2958 C CG1 . ILE A 1 454 ? 181.393 166.151 197.196 1.00 59.50  ? 454 ILE A CG1 1 
ATOM   2959 C CG2 . ILE A 1 454 ? 183.020 168.017 196.884 1.00 59.50  ? 454 ILE A CG2 1 
ATOM   2960 C CD1 . ILE A 1 454 ? 181.310 165.674 195.771 1.00 59.50  ? 454 ILE A CD1 1 
ATOM   2961 N N   . GLN A 1 455 ? 185.644 166.174 198.870 1.00 62.04  ? 455 GLN A N   1 
ATOM   2962 C CA  . GLN A 1 455 ? 186.954 166.679 199.269 1.00 62.04  ? 455 GLN A CA  1 
ATOM   2963 C C   . GLN A 1 455 ? 188.078 165.827 198.694 1.00 62.04  ? 455 GLN A C   1 
ATOM   2964 O O   . GLN A 1 455 ? 189.132 166.354 198.323 1.00 62.04  ? 455 GLN A O   1 
ATOM   2965 C CB  . GLN A 1 455 ? 187.048 166.745 200.791 1.00 62.04  ? 455 GLN A CB  1 
ATOM   2966 C CG  . GLN A 1 455 ? 186.408 167.986 201.385 1.00 62.04  ? 455 GLN A CG  1 
ATOM   2967 C CD  . GLN A 1 455 ? 186.426 167.988 202.899 1.00 62.04  ? 455 GLN A CD  1 
ATOM   2968 O OE1 . GLN A 1 455 ? 186.390 166.935 203.535 1.00 62.04  ? 455 GLN A OE1 1 
ATOM   2969 N NE2 . GLN A 1 455 ? 186.479 169.177 203.487 1.00 62.04  ? 455 GLN A NE2 1 
ATOM   2970 N N   . ALA A 1 456 ? 187.878 164.508 198.616 1.00 62.07  ? 456 ALA A N   1 
ATOM   2971 C CA  . ALA A 1 456 ? 188.884 163.655 197.993 1.00 62.07  ? 456 ALA A CA  1 
ATOM   2972 C C   . ALA A 1 456 ? 189.072 164.013 196.526 1.00 62.07  ? 456 ALA A C   1 
ATOM   2973 O O   . ALA A 1 456 ? 190.206 164.095 196.039 1.00 62.07  ? 456 ALA A O   1 
ATOM   2974 C CB  . ALA A 1 456 ? 188.494 162.186 198.142 1.00 62.07  ? 456 ALA A CB  1 
ATOM   2975 N N   . VAL A 1 457 ? 187.969 164.243 195.808 1.00 59.17  ? 457 VAL A N   1 
ATOM   2976 C CA  . VAL A 1 457 ? 188.065 164.633 194.402 1.00 59.17  ? 457 VAL A CA  1 
ATOM   2977 C C   . VAL A 1 457 ? 188.791 165.968 194.265 1.00 59.17  ? 457 VAL A C   1 
ATOM   2978 O O   . VAL A 1 457 ? 189.655 166.141 193.391 1.00 59.17  ? 457 VAL A O   1 
ATOM   2979 C CB  . VAL A 1 457 ? 186.661 164.685 193.771 1.00 59.17  ? 457 VAL A CB  1 
ATOM   2980 C CG1 . VAL A 1 457 ? 186.708 165.375 192.423 1.00 59.17  ? 457 VAL A CG1 1 
ATOM   2981 C CG2 . VAL A 1 457 ? 186.088 163.286 193.640 1.00 59.17  ? 457 VAL A CG2 1 
ATOM   2982 N N   . ILE A 1 458 ? 188.452 166.929 195.127 1.00 60.55  ? 458 ILE A N   1 
ATOM   2983 C CA  . ILE A 1 458 ? 189.074 168.249 195.055 1.00 60.55  ? 458 ILE A CA  1 
ATOM   2984 C C   . ILE A 1 458 ? 190.573 168.150 195.302 1.00 60.55  ? 458 ILE A C   1 
ATOM   2985 O O   . ILE A 1 458 ? 191.373 168.759 194.585 1.00 60.55  ? 458 ILE A O   1 
ATOM   2986 C CB  . ILE A 1 458 ? 188.399 169.213 196.048 1.00 60.55  ? 458 ILE A CB  1 
ATOM   2987 C CG1 . ILE A 1 458 ? 187.010 169.608 195.550 1.00 60.55  ? 458 ILE A CG1 1 
ATOM   2988 C CG2 . ILE A 1 458 ? 189.257 170.444 196.259 1.00 60.55  ? 458 ILE A CG2 1 
ATOM   2989 C CD1 . ILE A 1 458 ? 186.152 170.260 196.604 1.00 60.55  ? 458 ILE A CD1 1 
ATOM   2990 N N   . THR A 1 459 ? 190.979 167.383 196.317 1.00 64.27  ? 459 THR A N   1 
ATOM   2991 C CA  . THR A 1 459 ? 192.403 167.234 196.605 1.00 64.27  ? 459 THR A CA  1 
ATOM   2992 C C   . THR A 1 459 ? 193.129 166.524 195.470 1.00 64.27  ? 459 THR A C   1 
ATOM   2993 O O   . THR A 1 459 ? 194.254 166.900 195.110 1.00 64.27  ? 459 THR A O   1 
ATOM   2994 C CB  . THR A 1 459 ? 192.598 166.477 197.917 1.00 64.27  ? 459 THR A CB  1 
ATOM   2995 O OG1 . THR A 1 459 ? 191.747 167.037 198.924 1.00 64.27  ? 459 THR A OG1 1 
ATOM   2996 C CG2 . THR A 1 459 ? 194.043 166.574 198.372 1.00 64.27  ? 459 THR A CG2 1 
ATOM   2997 N N   . SER A 1 460 ? 192.504 165.493 194.895 1.00 65.19  ? 460 SER A N   1 
ATOM   2998 C CA  . SER A 1 460 ? 193.130 164.772 193.794 1.00 65.19  ? 460 SER A CA  1 
ATOM   2999 C C   . SER A 1 460 ? 193.379 165.694 192.609 1.00 65.19  ? 460 SER A C   1 
ATOM   3000 O O   . SER A 1 460 ? 194.465 165.683 192.018 1.00 65.19  ? 460 SER A O   1 
ATOM   3001 C CB  . SER A 1 460 ? 192.258 163.588 193.382 1.00 65.19  ? 460 SER A CB  1 
ATOM   3002 O OG  . SER A 1 460 ? 192.927 162.768 192.442 1.00 65.19  ? 460 SER A OG  1 
ATOM   3003 N N   . ARG A 1 461 ? 192.391 166.519 192.253 1.00 65.52  ? 461 ARG A N   1 
ATOM   3004 C CA  . ARG A 1 461 ? 192.622 167.408 191.120 1.00 65.52  ? 461 ARG A CA  1 
ATOM   3005 C C   . ARG A 1 461 ? 193.533 168.575 191.473 1.00 65.52  ? 461 ARG A C   1 
ATOM   3006 O O   . ARG A 1 461 ? 194.204 169.114 190.587 1.00 65.52  ? 461 ARG A O   1 
ATOM   3007 C CB  . ARG A 1 461 ? 191.313 167.934 190.542 1.00 65.52  ? 461 ARG A CB  1 
ATOM   3008 C CG  . ARG A 1 461 ? 191.449 168.219 189.056 1.00 65.52  ? 461 ARG A CG  1 
ATOM   3009 C CD  . ARG A 1 461 ? 190.300 169.020 188.499 1.00 65.52  ? 461 ARG A CD  1 
ATOM   3010 N NE  . ARG A 1 461 ? 190.457 169.262 187.069 1.00 65.52  ? 461 ARG A NE  1 
ATOM   3011 C CZ  . ARG A 1 461 ? 190.296 168.342 186.127 1.00 65.52  ? 461 ARG A CZ  1 
ATOM   3012 N NH1 . ARG A 1 461 ? 189.982 167.092 186.424 1.00 65.52  ? 461 ARG A NH1 1 
ATOM   3013 N NH2 . ARG A 1 461 ? 190.453 168.687 184.853 1.00 65.52  ? 461 ARG A NH2 1 
ATOM   3014 N N   . THR A 1 462 ? 193.570 168.990 192.741 1.00 67.03  ? 462 THR A N   1 
ATOM   3015 C CA  . THR A 1 462 ? 194.545 169.996 193.146 1.00 67.03  ? 462 THR A CA  1 
ATOM   3016 C C   . THR A 1 462 ? 195.959 169.485 192.931 1.00 67.03  ? 462 THR A C   1 
ATOM   3017 O O   . THR A 1 462 ? 196.816 170.203 192.405 1.00 67.03  ? 462 THR A O   1 
ATOM   3018 C CB  . THR A 1 462 ? 194.341 170.379 194.611 1.00 67.03  ? 462 THR A CB  1 
ATOM   3019 O OG1 . THR A 1 462 ? 192.958 170.661 194.847 1.00 67.03  ? 462 THR A OG1 1 
ATOM   3020 C CG2 . THR A 1 462 ? 195.166 171.603 194.956 1.00 67.03  ? 462 THR A CG2 1 
ATOM   3021 N N   . LEU A 1 463 ? 196.217 168.236 193.324 1.00 68.58  ? 463 LEU A N   1 
ATOM   3022 C CA  . LEU A 1 463 ? 197.526 167.646 193.070 1.00 68.58  ? 463 LEU A CA  1 
ATOM   3023 C C   . LEU A 1 463 ? 197.771 167.441 191.581 1.00 68.58  ? 463 LEU A C   1 
ATOM   3024 O O   . LEU A 1 463 ? 198.908 167.580 191.117 1.00 68.58  ? 463 LEU A O   1 
ATOM   3025 C CB  . LEU A 1 463 ? 197.663 166.322 193.818 1.00 68.58  ? 463 LEU A CB  1 
ATOM   3026 C CG  . LEU A 1 463 ? 197.798 166.436 195.336 1.00 68.58  ? 463 LEU A CG  1 
ATOM   3027 C CD1 . LEU A 1 463 ? 198.078 165.076 195.950 1.00 68.58  ? 463 LEU A CD1 1 
ATOM   3028 C CD2 . LEU A 1 463 ? 198.887 167.429 195.701 1.00 68.58  ? 463 LEU A CD2 1 
ATOM   3029 N N   . TYR A 1 464 ? 196.724 167.111 190.821 1.00 68.76  ? 464 TYR A N   1 
ATOM   3030 C CA  . TYR A 1 464 ? 196.892 166.826 189.399 1.00 68.76  ? 464 TYR A CA  1 
ATOM   3031 C C   . TYR A 1 464 ? 197.357 168.054 188.624 1.00 68.76  ? 464 TYR A C   1 
ATOM   3032 O O   . TYR A 1 464 ? 198.241 167.955 187.766 1.00 68.76  ? 464 TYR A O   1 
ATOM   3033 C CB  . TYR A 1 464 ? 195.579 166.291 188.828 1.00 68.76  ? 464 TYR A CB  1 
ATOM   3034 C CG  . TYR A 1 464 ? 195.534 166.193 187.322 1.00 68.76  ? 464 TYR A CG  1 
ATOM   3035 C CD1 . TYR A 1 464 ? 196.167 165.155 186.655 1.00 68.76  ? 464 TYR A CD1 1 
ATOM   3036 C CD2 . TYR A 1 464 ? 194.841 167.129 186.568 1.00 68.76  ? 464 TYR A CD2 1 
ATOM   3037 C CE1 . TYR A 1 464 ? 196.120 165.057 185.280 1.00 68.76  ? 464 TYR A CE1 1 
ATOM   3038 C CE2 . TYR A 1 464 ? 194.788 167.040 185.192 1.00 68.76  ? 464 TYR A CE2 1 
ATOM   3039 C CZ  . TYR A 1 464 ? 195.429 166.002 184.553 1.00 68.76  ? 464 TYR A CZ  1 
ATOM   3040 O OH  . TYR A 1 464 ? 195.379 165.910 183.182 1.00 68.76  ? 464 TYR A OH  1 
ATOM   3041 N N   . LEU A 1 465 ? 196.780 169.220 188.909 1.00 69.21  ? 465 LEU A N   1 
ATOM   3042 C CA  . LEU A 1 465 ? 197.060 170.430 188.143 1.00 69.21  ? 465 LEU A CA  1 
ATOM   3043 C C   . LEU A 1 465 ? 198.303 171.174 188.616 1.00 69.21  ? 465 LEU A C   1 
ATOM   3044 O O   . LEU A 1 465 ? 198.492 172.332 188.231 1.00 69.21  ? 465 LEU A O   1 
ATOM   3045 C CB  . LEU A 1 465 ? 195.859 171.377 188.188 1.00 69.21  ? 465 LEU A CB  1 
ATOM   3046 C CG  . LEU A 1 465 ? 194.575 170.922 187.499 1.00 69.21  ? 465 LEU A CG  1 
ATOM   3047 C CD1 . LEU A 1 465 ? 193.381 171.630 188.100 1.00 69.21  ? 465 LEU A CD1 1 
ATOM   3048 C CD2 . LEU A 1 465 ? 194.652 171.183 186.009 1.00 69.21  ? 465 LEU A CD2 1 
ATOM   3049 N N   . GLY A 1 466 ? 199.147 170.551 189.431 1.00 74.65  ? 466 GLY A N   1 
ATOM   3050 C CA  . GLY A 1 466 ? 200.363 171.185 189.890 1.00 74.65  ? 466 GLY A CA  1 
ATOM   3051 C C   . GLY A 1 466 ? 200.273 171.888 191.223 1.00 74.65  ? 466 GLY A C   1 
ATOM   3052 O O   . GLY A 1 466 ? 201.192 172.639 191.569 1.00 74.65  ? 466 GLY A O   1 
ATOM   3053 N N   . GLY A 1 467 ? 199.204 171.677 191.983 1.00 80.07  ? 467 GLY A N   1 
ATOM   3054 C CA  . GLY A 1 467 ? 199.066 172.280 193.289 1.00 80.07  ? 467 GLY A CA  1 
ATOM   3055 C C   . GLY A 1 467 ? 199.823 171.509 194.352 1.00 80.07  ? 467 GLY A C   1 
ATOM   3056 O O   . GLY A 1 467 ? 200.536 170.541 194.084 1.00 80.07  ? 467 GLY A O   1 
ATOM   3057 N N   . THR A 1 468 ? 199.654 171.957 195.594 1.00 89.55  ? 468 THR A N   1 
ATOM   3058 C CA  . THR A 1 468 ? 200.326 171.345 196.729 1.00 89.55  ? 468 THR A CA  1 
ATOM   3059 C C   . THR A 1 468 ? 199.363 171.270 197.903 1.00 89.55  ? 468 THR A C   1 
ATOM   3060 O O   . THR A 1 468 ? 198.324 171.934 197.927 1.00 89.55  ? 468 THR A O   1 
ATOM   3061 C CB  . THR A 1 468 ? 201.590 172.120 197.130 1.00 89.55  ? 468 THR A CB  1 
ATOM   3062 O OG1 . THR A 1 468 ? 202.396 171.310 197.995 1.00 89.55  ? 468 THR A OG1 1 
ATOM   3063 C CG2 . THR A 1 468 ? 201.222 173.397 197.855 1.00 89.55  ? 468 THR A CG2 1 
ATOM   3064 N N   . THR A 1 469 ? 199.718 170.440 198.879 1.00 94.46  ? 469 THR A N   1 
ATOM   3065 C CA  . THR A 1 469 ? 198.927 170.259 200.090 1.00 94.46  ? 469 THR A CA  1 
ATOM   3066 C C   . THR A 1 469 ? 199.589 171.036 201.221 1.00 94.46  ? 469 THR A C   1 
ATOM   3067 O O   . THR A 1 469 ? 200.720 170.732 201.614 1.00 94.46  ? 469 THR A O   1 
ATOM   3068 C CB  . THR A 1 469 ? 198.802 168.779 200.443 1.00 94.46  ? 469 THR A CB  1 
ATOM   3069 O OG1 . THR A 1 469 ? 200.106 168.187 200.494 1.00 94.46  ? 469 THR A OG1 1 
ATOM   3070 C CG2 . THR A 1 469 ? 197.962 168.054 199.404 1.00 94.46  ? 469 THR A CG2 1 
ATOM   3071 N N   . GLY A 1 470 ? 198.886 172.039 201.740 1.00 97.01  ? 470 GLY A N   1 
ATOM   3072 C CA  . GLY A 1 470 ? 199.401 172.856 202.812 1.00 97.01  ? 470 GLY A CA  1 
ATOM   3073 C C   . GLY A 1 470 ? 198.530 174.066 203.079 1.00 97.01  ? 470 GLY A C   1 
ATOM   3074 O O   . GLY A 1 470 ? 197.467 174.240 202.475 1.00 97.01  ? 470 GLY A O   1 
ATOM   3075 N N   . PRO A 1 471 ? 198.959 174.919 204.009 1.00 100.23 ? 471 PRO A N   1 
ATOM   3076 C CA  . PRO A 1 471 ? 198.203 176.147 204.285 1.00 100.23 ? 471 PRO A CA  1 
ATOM   3077 C C   . PRO A 1 471 ? 198.085 177.015 203.041 1.00 100.23 ? 471 PRO A C   1 
ATOM   3078 O O   . PRO A 1 471 ? 199.021 177.130 202.248 1.00 100.23 ? 471 PRO A O   1 
ATOM   3079 C CB  . PRO A 1 471 ? 199.021 176.846 205.378 1.00 100.23 ? 471 PRO A CB  1 
ATOM   3080 C CG  . PRO A 1 471 ? 200.054 175.885 205.830 1.00 100.23 ? 471 PRO A CG  1 
ATOM   3081 C CD  . PRO A 1 471 ? 200.019 174.653 204.995 1.00 100.23 ? 471 PRO A CD  1 
ATOM   3082 N N   . VAL A 1 472 ? 196.913 177.632 202.880 1.00 95.67  ? 472 VAL A N   1 
ATOM   3083 C CA  . VAL A 1 472 ? 196.662 178.461 201.705 1.00 95.67  ? 472 VAL A CA  1 
ATOM   3084 C C   . VAL A 1 472 ? 197.496 179.736 201.746 1.00 95.67  ? 472 VAL A C   1 
ATOM   3085 O O   . VAL A 1 472 ? 197.799 180.322 200.700 1.00 95.67  ? 472 VAL A O   1 
ATOM   3086 C CB  . VAL A 1 472 ? 195.157 178.768 201.593 1.00 95.67  ? 472 VAL A CB  1 
ATOM   3087 C CG1 . VAL A 1 472 ? 194.835 179.402 200.251 1.00 95.67  ? 472 VAL A CG1 1 
ATOM   3088 C CG2 . VAL A 1 472 ? 194.347 177.499 201.791 1.00 95.67  ? 472 VAL A CG2 1 
ATOM   3089 N N   . LYS A 1 473 ? 197.894 180.178 202.939 1.00 101.74 ? 473 LYS A N   1 
ATOM   3090 C CA  . LYS A 1 473 ? 198.594 181.448 203.086 1.00 101.74 ? 473 LYS A CA  1 
ATOM   3091 C C   . LYS A 1 473 ? 199.990 181.443 202.475 1.00 101.74 ? 473 LYS A C   1 
ATOM   3092 O O   . LYS A 1 473 ? 200.593 182.514 202.355 1.00 101.74 ? 473 LYS A O   1 
ATOM   3093 C CB  . LYS A 1 473 ? 198.685 181.822 204.566 1.00 101.74 ? 473 LYS A CB  1 
ATOM   3094 C CG  . LYS A 1 473 ? 197.353 181.783 205.296 1.00 101.74 ? 473 LYS A CG  1 
ATOM   3095 C CD  . LYS A 1 473 ? 196.348 182.733 204.664 1.00 101.74 ? 473 LYS A CD  1 
ATOM   3096 C CE  . LYS A 1 473 ? 196.685 184.181 204.977 1.00 101.74 ? 473 LYS A CE  1 
ATOM   3097 N NZ  . LYS A 1 473 ? 195.676 185.119 204.415 1.00 101.74 ? 473 LYS A NZ  1 
ATOM   3098 N N   . PHE A 1 474 ? 200.518 180.279 202.090 1.00 102.08 ? 474 PHE A N   1 
ATOM   3099 C CA  . PHE A 1 474 ? 201.875 180.188 201.569 1.00 102.08 ? 474 PHE A CA  1 
ATOM   3100 C C   . PHE A 1 474 ? 201.954 179.936 200.070 1.00 102.08 ? 474 PHE A C   1 
ATOM   3101 O O   . PHE A 1 474 ? 202.994 180.223 199.472 1.00 102.08 ? 474 PHE A O   1 
ATOM   3102 C CB  . PHE A 1 474 ? 202.647 179.075 202.293 1.00 102.08 ? 474 PHE A CB  1 
ATOM   3103 C CG  . PHE A 1 474 ? 202.938 179.376 203.735 1.00 102.08 ? 474 PHE A CG  1 
ATOM   3104 C CD1 . PHE A 1 474 ? 203.207 178.353 204.629 1.00 102.08 ? 474 PHE A CD1 1 
ATOM   3105 C CD2 . PHE A 1 474 ? 202.946 180.682 204.198 1.00 102.08 ? 474 PHE A CD2 1 
ATOM   3106 C CE1 . PHE A 1 474 ? 203.476 178.625 205.956 1.00 102.08 ? 474 PHE A CE1 1 
ATOM   3107 C CE2 . PHE A 1 474 ? 203.214 180.960 205.524 1.00 102.08 ? 474 PHE A CE2 1 
ATOM   3108 C CZ  . PHE A 1 474 ? 203.479 179.930 206.404 1.00 102.08 ? 474 PHE A CZ  1 
ATOM   3109 N N   . MET A 1 475 ? 200.898 179.414 199.454 1.00 95.30  ? 475 MET A N   1 
ATOM   3110 C CA  . MET A 1 475 ? 200.959 179.044 198.047 1.00 95.30  ? 475 MET A CA  1 
ATOM   3111 C C   . MET A 1 475 ? 200.969 180.273 197.143 1.00 95.30  ? 475 MET A C   1 
ATOM   3112 O O   . MET A 1 475 ? 200.411 181.323 197.472 1.00 95.30  ? 475 MET A O   1 
ATOM   3113 C CB  . MET A 1 475 ? 199.787 178.135 197.683 1.00 95.30  ? 475 MET A CB  1 
ATOM   3114 C CG  . MET A 1 475 ? 199.839 176.779 198.360 1.00 95.30  ? 475 MET A CG  1 
ATOM   3115 S SD  . MET A 1 475 ? 198.483 175.708 197.864 1.00 95.30  ? 475 MET A SD  1 
ATOM   3116 C CE  . MET A 1 475 ? 197.141 176.465 198.758 1.00 95.30  ? 475 MET A CE  1 
ATOM   3117 N N   . ASN A 1 476 ? 201.619 180.127 195.991 1.00 93.30  ? 476 ASN A N   1 
ATOM   3118 C CA  . ASN A 1 476 ? 201.730 181.189 195.004 1.00 93.30  ? 476 ASN A CA  1 
ATOM   3119 C C   . ASN A 1 476 ? 200.589 181.079 193.991 1.00 93.30  ? 476 ASN A C   1 
ATOM   3120 O O   . ASN A 1 476 ? 199.619 180.344 194.191 1.00 93.30  ? 476 ASN A O   1 
ATOM   3121 C CB  . ASN A 1 476 ? 203.101 181.146 194.334 1.00 93.30  ? 476 ASN A CB  1 
ATOM   3122 C CG  . ASN A 1 476 ? 203.513 179.744 193.937 1.00 93.30  ? 476 ASN A CG  1 
ATOM   3123 O OD1 . ASN A 1 476 ? 202.732 178.800 194.050 1.00 93.30  ? 476 ASN A OD1 1 
ATOM   3124 N ND2 . ASN A 1 476 ? 204.746 179.601 193.470 1.00 93.30  ? 476 ASN A ND2 1 
ATOM   3125 N N   . ASP A 1 477 ? 200.703 181.816 192.882 1.00 92.93  ? 477 ASP A N   1 
ATOM   3126 C CA  . ASP A 1 477 ? 199.586 181.953 191.950 1.00 92.93  ? 477 ASP A CA  1 
ATOM   3127 C C   . ASP A 1 477 ? 199.207 180.625 191.302 1.00 92.93  ? 477 ASP A C   1 
ATOM   3128 O O   . ASP A 1 477 ? 198.019 180.340 191.116 1.00 92.93  ? 477 ASP A O   1 
ATOM   3129 C CB  . ASP A 1 477 ? 199.925 182.987 190.877 1.00 92.93  ? 477 ASP A CB  1 
ATOM   3130 C CG  . ASP A 1 477 ? 199.779 184.410 191.374 1.00 92.93  ? 477 ASP A CG  1 
ATOM   3131 O OD1 . ASP A 1 477 ? 198.942 184.645 192.270 1.00 92.93  ? 477 ASP A OD1 1 
ATOM   3132 O OD2 . ASP A 1 477 ? 200.499 185.294 190.866 1.00 92.93  ? 477 ASP A OD2 1 
ATOM   3133 N N   . VAL A 1 478 ? 200.196 179.811 190.929 1.00 89.71  ? 478 VAL A N   1 
ATOM   3134 C CA  . VAL A 1 478 ? 199.906 178.579 190.197 1.00 89.71  ? 478 VAL A CA  1 
ATOM   3135 C C   . VAL A 1 478 ? 199.076 177.629 191.054 1.00 89.71  ? 478 VAL A C   1 
ATOM   3136 O O   . VAL A 1 478 ? 198.061 177.078 190.606 1.00 89.71  ? 478 VAL A O   1 
ATOM   3137 C CB  . VAL A 1 478 ? 201.213 177.916 189.728 1.00 89.71  ? 478 VAL A CB  1 
ATOM   3138 C CG1 . VAL A 1 478 ? 200.915 176.812 188.728 1.00 89.71  ? 478 VAL A CG1 1 
ATOM   3139 C CG2 . VAL A 1 478 ? 202.144 178.957 189.127 1.00 89.71  ? 478 VAL A CG2 1 
ATOM   3140 N N   . GLN A 1 479 ? 199.486 177.436 192.306 1.00 87.18  ? 479 GLN A N   1 
ATOM   3141 C CA  . GLN A 1 479 ? 198.765 176.525 193.185 1.00 87.18  ? 479 GLN A CA  1 
ATOM   3142 C C   . GLN A 1 479 ? 197.408 177.090 193.589 1.00 87.18  ? 479 GLN A C   1 
ATOM   3143 O O   . GLN A 1 479 ? 196.450 176.332 193.787 1.00 87.18  ? 479 GLN A O   1 
ATOM   3144 C CB  . GLN A 1 479 ? 199.633 176.214 194.401 1.00 87.18  ? 479 GLN A CB  1 
ATOM   3145 C CG  . GLN A 1 479 ? 201.032 175.752 194.005 1.00 87.18  ? 479 GLN A CG  1 
ATOM   3146 C CD  . GLN A 1 479 ? 202.033 175.812 195.139 1.00 87.18  ? 479 GLN A CD  1 
ATOM   3147 O OE1 . GLN A 1 479 ? 202.098 176.793 195.876 1.00 87.18  ? 479 GLN A OE1 1 
ATOM   3148 N NE2 . GLN A 1 479 ? 202.828 174.760 195.279 1.00 87.18  ? 479 GLN A NE2 1 
ATOM   3149 N N   . LEU A 1 480 ? 197.297 178.415 193.691 1.00 82.84  ? 480 LEU A N   1 
ATOM   3150 C CA  . LEU A 1 480 ? 196.000 179.027 193.958 1.00 82.84  ? 480 LEU A CA  1 
ATOM   3151 C C   . LEU A 1 480 ? 195.036 178.807 192.795 1.00 82.84  ? 480 LEU A C   1 
ATOM   3152 O O   . LEU A 1 480 ? 193.853 178.507 193.005 1.00 82.84  ? 480 LEU A O   1 
ATOM   3153 C CB  . LEU A 1 480 ? 196.187 180.513 194.248 1.00 82.84  ? 480 LEU A CB  1 
ATOM   3154 C CG  . LEU A 1 480 ? 196.691 180.791 195.666 1.00 82.84  ? 480 LEU A CG  1 
ATOM   3155 C CD1 . LEU A 1 480 ? 197.166 182.227 195.814 1.00 82.84  ? 480 LEU A CD1 1 
ATOM   3156 C CD2 . LEU A 1 480 ? 195.621 180.465 196.694 1.00 82.84  ? 480 LEU A CD2 1 
ATOM   3157 N N   . ALA A 1 481 ? 195.526 178.941 191.561 1.00 77.92  ? 481 ALA A N   1 
ATOM   3158 C CA  . ALA A 1 481 ? 194.695 178.641 190.399 1.00 77.92  ? 481 ALA A CA  1 
ATOM   3159 C C   . ALA A 1 481 ? 194.320 177.166 190.364 1.00 77.92  ? 481 ALA A C   1 
ATOM   3160 O O   . ALA A 1 481 ? 193.211 176.805 189.945 1.00 77.92  ? 481 ALA A O   1 
ATOM   3161 C CB  . ALA A 1 481 ? 195.420 179.044 189.117 1.00 77.92  ? 481 ALA A CB  1 
ATOM   3162 N N   . ALA A 1 482 ? 195.238 176.297 190.792 1.00 73.85  ? 482 ALA A N   1 
ATOM   3163 C CA  . ALA A 1 482 ? 194.917 174.878 190.897 1.00 73.85  ? 482 ALA A CA  1 
ATOM   3164 C C   . ALA A 1 482 ? 193.773 174.642 191.877 1.00 73.85  ? 482 ALA A C   1 
ATOM   3165 O O   . ALA A 1 482 ? 192.860 173.857 191.597 1.00 73.85  ? 482 ALA A O   1 
ATOM   3166 C CB  . ALA A 1 482 ? 196.157 174.091 191.315 1.00 73.85  ? 482 ALA A CB  1 
ATOM   3167 N N   . LEU A 1 483 ? 193.801 175.319 193.030 1.00 72.79  ? 483 LEU A N   1 
ATOM   3168 C CA  . LEU A 1 483 ? 192.683 175.221 193.970 1.00 72.79  ? 483 LEU A CA  1 
ATOM   3169 C C   . LEU A 1 483 ? 191.384 175.727 193.358 1.00 72.79  ? 483 LEU A C   1 
ATOM   3170 O O   . LEU A 1 483 ? 190.318 175.128 193.557 1.00 72.79  ? 483 LEU A O   1 
ATOM   3171 C CB  . LEU A 1 483 ? 192.971 176.001 195.250 1.00 72.79  ? 483 LEU A CB  1 
ATOM   3172 C CG  . LEU A 1 483 ? 193.773 175.355 196.368 1.00 72.79  ? 483 LEU A CG  1 
ATOM   3173 C CD1 . LEU A 1 483 ? 193.899 176.353 197.490 1.00 72.79  ? 483 LEU A CD1 1 
ATOM   3174 C CD2 . LEU A 1 483 ? 193.068 174.104 196.845 1.00 72.79  ? 483 LEU A CD2 1 
ATOM   3175 N N   . ASP A 1 484 ? 191.447 176.853 192.649 1.00 70.68  ? 484 ASP A N   1 
ATOM   3176 C CA  . ASP A 1 484 ? 190.250 177.403 192.021 1.00 70.68  ? 484 ASP A CA  1 
ATOM   3177 C C   . ASP A 1 484 ? 189.622 176.392 191.067 1.00 70.68  ? 484 ASP A C   1 
ATOM   3178 O O   . ASP A 1 484 ? 188.412 176.119 191.124 1.00 70.68  ? 484 ASP A O   1 
ATOM   3179 C CB  . ASP A 1 484 ? 190.611 178.692 191.283 1.00 70.68  ? 484 ASP A CB  1 
ATOM   3180 C CG  . ASP A 1 484 ? 189.419 179.588 191.052 1.00 70.68  ? 484 ASP A CG  1 
ATOM   3181 O OD1 . ASP A 1 484 ? 188.276 179.130 191.252 1.00 70.68  ? 484 ASP A OD1 1 
ATOM   3182 O OD2 . ASP A 1 484 ? 189.628 180.755 190.666 1.00 70.68  ? 484 ASP A OD2 1 
ATOM   3183 N N   . HIS A 1 485 ? 190.445 175.810 190.194 1.00 67.51  ? 485 HIS A N   1 
ATOM   3184 C CA  . HIS A 1 485 ? 189.940 174.828 189.244 1.00 67.51  ? 485 HIS A CA  1 
ATOM   3185 C C   . HIS A 1 485 ? 189.420 173.586 189.956 1.00 67.51  ? 485 HIS A C   1 
ATOM   3186 O O   . HIS A 1 485 ? 188.407 173.009 189.547 1.00 67.51  ? 485 HIS A O   1 
ATOM   3187 C CB  . HIS A 1 485 ? 191.032 174.467 188.240 1.00 67.51  ? 485 HIS A CB  1 
ATOM   3188 C CG  . HIS A 1 485 ? 191.424 175.601 187.346 1.00 67.51  ? 485 HIS A CG  1 
ATOM   3189 N ND1 . HIS A 1 485 ? 190.568 176.637 187.042 1.00 67.51  ? 485 HIS A ND1 1 
ATOM   3190 C CD2 . HIS A 1 485 ? 192.580 175.865 186.693 1.00 67.51  ? 485 HIS A CD2 1 
ATOM   3191 C CE1 . HIS A 1 485 ? 191.179 177.489 186.238 1.00 67.51  ? 485 HIS A CE1 1 
ATOM   3192 N NE2 . HIS A 1 485 ? 192.401 177.044 186.011 1.00 67.51  ? 485 HIS A NE2 1 
ATOM   3193 N N   . ALA A 1 486 ? 190.090 173.164 191.032 1.00 64.75  ? 486 ALA A N   1 
ATOM   3194 C CA  . ALA A 1 486 ? 189.639 171.987 191.768 1.00 64.75  ? 486 ALA A CA  1 
ATOM   3195 C C   . ALA A 1 486 ? 188.261 172.201 192.384 1.00 64.75  ? 486 ALA A C   1 
ATOM   3196 O O   . ALA A 1 486 ? 187.405 171.309 192.333 1.00 64.75  ? 486 ALA A O   1 
ATOM   3197 C CB  . ALA A 1 486 ? 190.658 171.628 192.845 1.00 64.75  ? 486 ALA A CB  1 
ATOM   3198 N N   . TYR A 1 487 ? 188.029 173.372 192.980 1.00 63.79  ? 487 TYR A N   1 
ATOM   3199 C CA  . TYR A 1 487 ? 186.713 173.669 193.543 1.00 63.79  ? 487 TYR A CA  1 
ATOM   3200 C C   . TYR A 1 487 ? 185.636 173.715 192.464 1.00 63.79  ? 487 TYR A C   1 
ATOM   3201 O O   . TYR A 1 487 ? 184.563 173.106 192.609 1.00 63.79  ? 487 TYR A O   1 
ATOM   3202 C CB  . TYR A 1 487 ? 186.758 174.983 194.322 1.00 63.79  ? 487 TYR A CB  1 
ATOM   3203 C CG  . TYR A 1 487 ? 187.427 174.882 195.673 1.00 63.79  ? 487 TYR A CG  1 
ATOM   3204 C CD1 . TYR A 1 487 ? 187.589 173.658 196.297 1.00 63.79  ? 487 TYR A CD1 1 
ATOM   3205 C CD2 . TYR A 1 487 ? 187.903 176.010 196.320 1.00 63.79  ? 487 TYR A CD2 1 
ATOM   3206 C CE1 . TYR A 1 487 ? 188.191 173.563 197.533 1.00 63.79  ? 487 TYR A CE1 1 
ATOM   3207 C CE2 . TYR A 1 487 ? 188.512 175.923 197.553 1.00 63.79  ? 487 TYR A CE2 1 
ATOM   3208 C CZ  . TYR A 1 487 ? 188.653 174.697 198.155 1.00 63.79  ? 487 TYR A CZ  1 
ATOM   3209 O OH  . TYR A 1 487 ? 189.260 174.605 199.384 1.00 63.79  ? 487 TYR A OH  1 
ATOM   3210 N N   . THR A 1 488 ? 185.896 174.440 191.372 1.00 61.27  ? 488 THR A N   1 
ATOM   3211 C CA  . THR A 1 488 ? 184.888 174.503 190.320 1.00 61.27  ? 488 THR A CA  1 
ATOM   3212 C C   . THR A 1 488 ? 184.691 173.160 189.626 1.00 61.27  ? 488 THR A C   1 
ATOM   3213 O O   . THR A 1 488 ? 183.676 172.970 188.950 1.00 61.27  ? 488 THR A O   1 
ATOM   3214 C CB  . THR A 1 488 ? 185.244 175.581 189.299 1.00 61.27  ? 488 THR A CB  1 
ATOM   3215 O OG1 . THR A 1 488 ? 186.406 175.183 188.564 1.00 61.27  ? 488 THR A OG1 1 
ATOM   3216 C CG2 . THR A 1 488 ? 185.509 176.903 189.995 1.00 61.27  ? 488 THR A CG2 1 
ATOM   3217 N N   . TYR A 1 489 ? 185.634 172.229 189.778 1.00 60.61  ? 489 TYR A N   1 
ATOM   3218 C CA  . TYR A 1 489 ? 185.457 170.882 189.247 1.00 60.61  ? 489 TYR A CA  1 
ATOM   3219 C C   . TYR A 1 489 ? 184.651 170.003 190.199 1.00 60.61  ? 489 TYR A C   1 
ATOM   3220 O O   . TYR A 1 489 ? 183.855 169.171 189.752 1.00 60.61  ? 489 TYR A O   1 
ATOM   3221 C CB  . TYR A 1 489 ? 186.825 170.260 188.963 1.00 60.61  ? 489 TYR A CB  1 
ATOM   3222 C CG  . TYR A 1 489 ? 186.786 168.828 188.485 1.00 60.61  ? 489 TYR A CG  1 
ATOM   3223 C CD1 . TYR A 1 489 ? 186.381 168.516 187.196 1.00 60.61  ? 489 TYR A CD1 1 
ATOM   3224 C CD2 . TYR A 1 489 ? 187.172 167.788 189.319 1.00 60.61  ? 489 TYR A CD2 1 
ATOM   3225 C CE1 . TYR A 1 489 ? 186.352 167.209 186.755 1.00 60.61  ? 489 TYR A CE1 1 
ATOM   3226 C CE2 . TYR A 1 489 ? 187.148 166.480 188.886 1.00 60.61  ? 489 TYR A CE2 1 
ATOM   3227 C CZ  . TYR A 1 489 ? 186.736 166.196 187.605 1.00 60.61  ? 489 TYR A CZ  1 
ATOM   3228 O OH  . TYR A 1 489 ? 186.709 164.893 187.170 1.00 60.61  ? 489 TYR A OH  1 
ATOM   3229 N N   . GLY A 1 490 ? 184.846 170.166 191.510 1.00 58.91  ? 490 GLY A N   1 
ATOM   3230 C CA  . GLY A 1 490 ? 184.042 169.422 192.468 1.00 58.91  ? 490 GLY A CA  1 
ATOM   3231 C C   . GLY A 1 490 ? 182.592 169.865 192.494 1.00 58.91  ? 490 GLY A C   1 
ATOM   3232 O O   . GLY A 1 490 ? 181.701 169.087 192.869 1.00 58.91  ? 490 GLY A O   1 
ATOM   3233 N N   . LEU A 1 491 ? 182.333 171.116 192.107 1.00 57.78  ? 491 LEU A N   1 
ATOM   3234 C CA  . LEU A 1 491 ? 180.946 171.549 191.948 1.00 57.78  ? 491 LEU A CA  1 
ATOM   3235 C C   . LEU A 1 491 ? 180.196 170.675 190.944 1.00 57.78  ? 491 LEU A C   1 
ATOM   3236 O O   . LEU A 1 491 ? 178.996 170.417 191.114 1.00 57.78  ? 491 LEU A O   1 
ATOM   3237 C CB  . LEU A 1 491 ? 180.901 173.015 191.523 1.00 57.78  ? 491 LEU A CB  1 
ATOM   3238 C CG  . LEU A 1 491 ? 179.657 173.807 191.924 1.00 57.78  ? 491 LEU A CG  1 
ATOM   3239 C CD1 . LEU A 1 491 ? 179.291 173.542 193.371 1.00 57.78  ? 491 LEU A CD1 1 
ATOM   3240 C CD2 . LEU A 1 491 ? 179.884 175.288 191.695 1.00 57.78  ? 491 LEU A CD2 1 
ATOM   3241 N N   . LEU A 1 492 ? 180.884 170.196 189.904 1.00 56.99  ? 492 LEU A N   1 
ATOM   3242 C CA  . LEU A 1 492 ? 180.249 169.307 188.935 1.00 56.99  ? 492 LEU A CA  1 
ATOM   3243 C C   . LEU A 1 492 ? 179.841 167.985 189.576 1.00 56.99  ? 492 LEU A C   1 
ATOM   3244 O O   . LEU A 1 492 ? 178.779 167.434 189.263 1.00 56.99  ? 492 LEU A O   1 
ATOM   3245 C CB  . LEU A 1 492 ? 181.189 169.059 187.757 1.00 56.99  ? 492 LEU A CB  1 
ATOM   3246 C CG  . LEU A 1 492 ? 181.259 170.150 186.690 1.00 56.99  ? 492 LEU A CG  1 
ATOM   3247 C CD1 . LEU A 1 492 ? 182.291 169.795 185.638 1.00 56.99  ? 492 LEU A CD1 1 
ATOM   3248 C CD2 . LEU A 1 492 ? 179.898 170.362 186.056 1.00 56.99  ? 492 LEU A CD2 1 
ATOM   3249 N N   . TRP A 1 493 ? 180.682 167.449 190.462 1.00 57.69  ? 493 TRP A N   1 
ATOM   3250 C CA  . TRP A 1 493 ? 180.323 166.221 191.162 1.00 57.69  ? 493 TRP A CA  1 
ATOM   3251 C C   . TRP A 1 493 ? 179.129 166.444 192.080 1.00 57.69  ? 493 TRP A C   1 
ATOM   3252 O O   . TRP A 1 493 ? 178.264 165.567 192.211 1.00 57.69  ? 493 TRP A O   1 
ATOM   3253 C CB  . TRP A 1 493 ? 181.523 165.696 191.945 1.00 57.69  ? 493 TRP A CB  1 
ATOM   3254 C CG  . TRP A 1 493 ? 182.561 165.079 191.068 1.00 57.69  ? 493 TRP A CG  1 
ATOM   3255 C CD1 . TRP A 1 493 ? 183.337 165.716 190.146 1.00 57.69  ? 493 TRP A CD1 1 
ATOM   3256 C CD2 . TRP A 1 493 ? 182.931 163.697 191.017 1.00 57.69  ? 493 TRP A CD2 1 
ATOM   3257 N NE1 . TRP A 1 493 ? 184.170 164.819 189.528 1.00 57.69  ? 493 TRP A NE1 1 
ATOM   3258 C CE2 . TRP A 1 493 ? 183.941 163.572 190.045 1.00 57.69  ? 493 TRP A CE2 1 
ATOM   3259 C CE3 . TRP A 1 493 ? 182.508 162.555 191.701 1.00 57.69  ? 493 TRP A CE3 1 
ATOM   3260 C CZ2 . TRP A 1 493 ? 184.534 162.351 189.741 1.00 57.69  ? 493 TRP A CZ2 1 
ATOM   3261 C CZ3 . TRP A 1 493 ? 183.098 161.344 191.397 1.00 57.69  ? 493 TRP A CZ3 1 
ATOM   3262 C CH2 . TRP A 1 493 ? 184.100 161.252 190.426 1.00 57.69  ? 493 TRP A CH2 1 
ATOM   3263 N N   . VAL A 1 494 ? 179.061 167.612 192.720 1.00 57.27  ? 494 VAL A N   1 
ATOM   3264 C CA  . VAL A 1 494 ? 177.878 167.934 193.519 1.00 57.27  ? 494 VAL A CA  1 
ATOM   3265 C C   . VAL A 1 494 ? 176.630 167.953 192.639 1.00 57.27  ? 494 VAL A C   1 
ATOM   3266 O O   . VAL A 1 494 ? 175.566 167.443 193.023 1.00 57.27  ? 494 VAL A O   1 
ATOM   3267 C CB  . VAL A 1 494 ? 178.070 169.268 194.261 1.00 57.27  ? 494 VAL A CB  1 
ATOM   3268 C CG1 . VAL A 1 494 ? 176.869 169.558 195.134 1.00 57.27  ? 494 VAL A CG1 1 
ATOM   3269 C CG2 . VAL A 1 494 ? 179.328 169.228 195.104 1.00 57.27  ? 494 VAL A CG2 1 
ATOM   3270 N N   . ALA A 1 495 ? 176.740 168.540 191.444 1.00 58.54  ? 495 ALA A N   1 
ATOM   3271 C CA  . ALA A 1 495 ? 175.602 168.571 190.525 1.00 58.54  ? 495 ALA A CA  1 
ATOM   3272 C C   . ALA A 1 495 ? 175.183 167.166 190.100 1.00 58.54  ? 495 ALA A C   1 
ATOM   3273 O O   . ALA A 1 495 ? 173.986 166.869 189.995 1.00 58.54  ? 495 ALA A O   1 
ATOM   3274 C CB  . ALA A 1 495 ? 175.941 169.423 189.304 1.00 58.54  ? 495 ALA A CB  1 
ATOM   3275 N N   . GLY A 1 496 ? 176.154 166.292 189.835 1.00 59.25  ? 496 GLY A N   1 
ATOM   3276 C CA  . GLY A 1 496 ? 175.822 164.914 189.498 1.00 59.25  ? 496 GLY A CA  1 
ATOM   3277 C C   . GLY A 1 496 ? 175.126 164.187 190.634 1.00 59.25  ? 496 GLY A C   1 
ATOM   3278 O O   . GLY A 1 496 ? 174.195 163.402 190.412 1.00 59.25  ? 496 GLY A O   1 
ATOM   3279 N N   . ALA A 1 497 ? 175.568 164.437 191.868 1.00 59.13  ? 497 ALA A N   1 
ATOM   3280 C CA  . ALA A 1 497 ? 174.878 163.871 193.023 1.00 59.13  ? 497 ALA A CA  1 
ATOM   3281 C C   . ALA A 1 497 ? 173.438 164.361 193.093 1.00 59.13  ? 497 ALA A C   1 
ATOM   3282 O O   . ALA A 1 497 ? 172.526 163.590 193.411 1.00 59.13  ? 497 ALA A O   1 
ATOM   3283 C CB  . ALA A 1 497 ? 175.630 164.216 194.307 1.00 59.13  ? 497 ALA A CB  1 
ATOM   3284 N N   . ALA A 1 498 ? 173.213 165.644 192.797 1.00 60.22  ? 498 ALA A N   1 
ATOM   3285 C CA  . ALA A 1 498 ? 171.847 166.164 192.764 1.00 60.22  ? 498 ALA A CA  1 
ATOM   3286 C C   . ALA A 1 498 ? 171.015 165.474 191.686 1.00 60.22  ? 498 ALA A C   1 
ATOM   3287 O O   . ALA A 1 498 ? 169.825 165.195 191.887 1.00 60.22  ? 498 ALA A O   1 
ATOM   3288 C CB  . ALA A 1 498 ? 171.862 167.675 192.541 1.00 60.22  ? 498 ALA A CB  1 
ATOM   3289 N N   . ILE A 1 499 ? 171.624 165.205 190.529 1.00 62.71  ? 499 ILE A N   1 
ATOM   3290 C CA  . ILE A 1 499 ? 170.926 164.480 189.467 1.00 62.71  ? 499 ILE A CA  1 
ATOM   3291 C C   . ILE A 1 499 ? 170.494 163.103 189.956 1.00 62.71  ? 499 ILE A C   1 
ATOM   3292 O O   . ILE A 1 499 ? 169.362 162.664 189.710 1.00 62.71  ? 499 ILE A O   1 
ATOM   3293 C CB  . ILE A 1 499 ? 171.815 164.372 188.214 1.00 62.71  ? 499 ILE A CB  1 
ATOM   3294 C CG1 . ILE A 1 499 ? 171.886 165.710 187.482 1.00 62.71  ? 499 ILE A CG1 1 
ATOM   3295 C CG2 . ILE A 1 499 ? 171.297 163.291 187.281 1.00 62.71  ? 499 ILE A CG2 1 
ATOM   3296 C CD1 . ILE A 1 499 ? 172.740 165.669 186.236 1.00 62.71  ? 499 ILE A CD1 1 
ATOM   3297 N N   . ILE A 1 500 ? 171.393 162.398 190.647 1.00 61.36  ? 500 ILE A N   1 
ATOM   3298 C CA  . ILE A 1 500 ? 171.047 161.083 191.188 1.00 61.36  ? 500 ILE A CA  1 
ATOM   3299 C C   . ILE A 1 500 ? 169.912 161.203 192.199 1.00 61.36  ? 500 ILE A C   1 
ATOM   3300 O O   . ILE A 1 500 ? 168.987 160.377 192.223 1.00 61.36  ? 500 ILE A O   1 
ATOM   3301 C CB  . ILE A 1 500 ? 172.288 160.414 191.808 1.00 61.36  ? 500 ILE A CB  1 
ATOM   3302 C CG1 . ILE A 1 500 ? 173.279 160.011 190.718 1.00 61.36  ? 500 ILE A CG1 1 
ATOM   3303 C CG2 . ILE A 1 500 ? 171.889 159.203 192.631 1.00 61.36  ? 500 ILE A CG2 1 
ATOM   3304 C CD1 . ILE A 1 500 ? 174.574 159.454 191.256 1.00 61.36  ? 500 ILE A CD1 1 
ATOM   3305 N N   . VAL A 1 501 ? 169.967 162.233 193.049 1.00 63.49  ? 501 VAL A N   1 
ATOM   3306 C CA  . VAL A 1 501 ? 168.918 162.443 194.044 1.00 63.49  ? 501 VAL A CA  1 
ATOM   3307 C C   . VAL A 1 501 ? 167.567 162.603 193.366 1.00 63.49  ? 501 VAL A C   1 
ATOM   3308 O O   . VAL A 1 501 ? 166.568 162.017 193.795 1.00 63.49  ? 501 VAL A O   1 
ATOM   3309 C CB  . VAL A 1 501 ? 169.246 163.664 194.923 1.00 63.49  ? 501 VAL A CB  1 
ATOM   3310 C CG1 . VAL A 1 501 ? 168.057 164.026 195.794 1.00 63.49  ? 501 VAL A CG1 1 
ATOM   3311 C CG2 . VAL A 1 501 ? 170.461 163.394 195.775 1.00 63.49  ? 501 VAL A CG2 1 
ATOM   3312 N N   . GLY A 1 502 ? 167.512 163.400 192.301 1.00 65.54  ? 502 GLY A N   1 
ATOM   3313 C CA  . GLY A 1 502 ? 166.250 163.587 191.599 1.00 65.54  ? 502 GLY A CA  1 
ATOM   3314 C C   . GLY A 1 502 ? 165.763 162.331 190.903 1.00 65.54  ? 502 GLY A C   1 
ATOM   3315 O O   . GLY A 1 502 ? 164.567 162.015 190.931 1.00 65.54  ? 502 GLY A O   1 
ATOM   3316 N N   . GLY A 1 503 ? 166.677 161.602 190.262 1.00 65.37  ? 503 GLY A N   1 
ATOM   3317 C CA  . GLY A 1 503 ? 166.287 160.358 189.623 1.00 65.37  ? 503 GLY A CA  1 
ATOM   3318 C C   . GLY A 1 503 ? 165.695 159.370 190.607 1.00 65.37  ? 503 GLY A C   1 
ATOM   3319 O O   . GLY A 1 503 ? 164.750 158.647 190.284 1.00 65.37  ? 503 GLY A O   1 
ATOM   3320 N N   . MET A 1 504 ? 166.240 159.328 191.823 1.00 66.91  ? 504 MET A N   1 
ATOM   3321 C CA  . MET A 1 504 ? 165.693 158.436 192.839 1.00 66.91  ? 504 MET A CA  1 
ATOM   3322 C C   . MET A 1 504 ? 164.410 158.981 193.462 1.00 66.91  ? 504 MET A C   1 
ATOM   3323 O O   . MET A 1 504 ? 163.535 158.199 193.846 1.00 66.91  ? 504 MET A O   1 
ATOM   3324 C CB  . MET A 1 504 ? 166.747 158.170 193.912 1.00 66.91  ? 504 MET A CB  1 
ATOM   3325 C CG  . MET A 1 504 ? 166.309 157.212 194.995 1.00 66.91  ? 504 MET A CG  1 
ATOM   3326 S SD  . MET A 1 504 ? 167.639 156.963 196.171 1.00 66.91  ? 504 MET A SD  1 
ATOM   3327 C CE  . MET A 1 504 ? 167.608 158.553 196.973 1.00 66.91  ? 504 MET A CE  1 
ATOM   3328 N N   . ALA A 1 505 ? 164.277 160.304 193.573 1.00 66.69  ? 505 ALA A N   1 
ATOM   3329 C CA  . ALA A 1 505 ? 163.055 160.906 194.094 1.00 66.69  ? 505 ALA A CA  1 
ATOM   3330 C C   . ALA A 1 505 ? 161.910 160.872 193.094 1.00 66.69  ? 505 ALA A C   1 
ATOM   3331 O O   . ALA A 1 505 ? 160.780 161.207 193.459 1.00 66.69  ? 505 ALA A O   1 
ATOM   3332 C CB  . ALA A 1 505 ? 163.317 162.351 194.520 1.00 66.69  ? 505 ALA A CB  1 
ATOM   3333 N N   . LEU A 1 506 ? 162.180 160.502 191.846 1.00 66.93  ? 506 LEU A N   1 
ATOM   3334 C CA  . LEU A 1 506 ? 161.122 160.320 190.857 1.00 66.93  ? 506 LEU A CA  1 
ATOM   3335 C C   . LEU A 1 506 ? 160.154 159.192 191.215 1.00 66.93  ? 506 LEU A C   1 
ATOM   3336 O O   . LEU A 1 506 ? 159.195 158.945 190.479 1.00 66.93  ? 506 LEU A O   1 
ATOM   3337 C CB  . LEU A 1 506 ? 161.736 160.044 189.483 1.00 66.93  ? 506 LEU A CB  1 
ATOM   3338 C CG  . LEU A 1 506 ? 160.992 160.550 188.248 1.00 66.93  ? 506 LEU A CG  1 
ATOM   3339 C CD1 . LEU A 1 506 ? 160.753 162.044 188.344 1.00 66.93  ? 506 LEU A CD1 1 
ATOM   3340 C CD2 . LEU A 1 506 ? 161.773 160.208 186.994 1.00 66.93  ? 506 LEU A CD2 1 
ATOM   3341 N N   . PHE A 1 507 ? 160.387 158.502 192.330 1.00 69.28  ? 507 PHE A N   1 
ATOM   3342 C CA  . PHE A 1 507 ? 159.607 157.332 192.722 1.00 69.28  ? 507 PHE A CA  1 
ATOM   3343 C C   . PHE A 1 507 ? 158.932 157.525 194.077 1.00 69.28  ? 507 PHE A C   1 
ATOM   3344 O O   . PHE A 1 507 ? 158.918 156.618 194.911 1.00 69.28  ? 507 PHE A O   1 
ATOM   3345 C CB  . PHE A 1 507 ? 160.485 156.083 192.759 1.00 69.28  ? 507 PHE A CB  1 
ATOM   3346 C CG  . PHE A 1 507 ? 160.948 155.620 191.411 1.00 69.28  ? 507 PHE A CG  1 
ATOM   3347 C CD1 . PHE A 1 507 ? 160.175 154.753 190.658 1.00 69.28  ? 507 PHE A CD1 1 
ATOM   3348 C CD2 . PHE A 1 507 ? 162.164 156.039 190.902 1.00 69.28  ? 507 PHE A CD2 1 
ATOM   3349 C CE1 . PHE A 1 507 ? 160.601 154.323 189.418 1.00 69.28  ? 507 PHE A CE1 1 
ATOM   3350 C CE2 . PHE A 1 507 ? 162.596 155.611 189.662 1.00 69.28  ? 507 PHE A CE2 1 
ATOM   3351 C CZ  . PHE A 1 507 ? 161.813 154.752 188.920 1.00 69.28  ? 507 PHE A CZ  1 
ATOM   3352 N N   . ILE A 1 508 ? 158.355 158.700 194.321 1.00 69.25  ? 508 ILE A N   1 
ATOM   3353 C CA  . ILE A 1 508 ? 157.718 158.956 195.613 1.00 69.25  ? 508 ILE A CA  1 
ATOM   3354 C C   . ILE A 1 508 ? 156.317 158.359 195.652 1.00 69.25  ? 508 ILE A C   1 
ATOM   3355 O O   . ILE A 1 508 ? 156.016 157.488 196.476 1.00 69.25  ? 508 ILE A O   1 
ATOM   3356 C CB  . ILE A 1 508 ? 157.697 160.463 195.922 1.00 69.25  ? 508 ILE A CB  1 
ATOM   3357 C CG1 . ILE A 1 508 ? 159.119 160.986 196.121 1.00 69.25  ? 508 ILE A CG1 1 
ATOM   3358 C CG2 . ILE A 1 508 ? 156.867 160.734 197.163 1.00 69.25  ? 508 ILE A CG2 1 
ATOM   3359 C CD1 . ILE A 1 508 ? 159.766 160.528 197.402 1.00 69.25  ? 508 ILE A CD1 1 
ATOM   3360 N N   . GLY A 1 509 ? 155.438 158.817 194.767 1.00 68.38  ? 509 GLY A N   1 
ATOM   3361 C CA  . GLY A 1 509 ? 154.109 158.256 194.662 1.00 68.38  ? 509 GLY A CA  1 
ATOM   3362 C C   . GLY A 1 509 ? 153.066 158.852 195.581 1.00 68.38  ? 509 GLY A C   1 
ATOM   3363 O O   . GLY A 1 509 ? 151.895 158.466 195.489 1.00 68.38  ? 509 GLY A O   1 
ATOM   3364 N N   . TYR A 1 510 ? 153.445 159.771 196.463 1.00 69.65  ? 510 TYR A N   1 
ATOM   3365 C CA  . TYR A 1 510 ? 152.471 160.413 197.333 1.00 69.65  ? 510 TYR A CA  1 
ATOM   3366 C C   . TYR A 1 510 ? 151.583 161.359 196.534 1.00 69.65  ? 510 TYR A C   1 
ATOM   3367 O O   . TYR A 1 510 ? 151.976 161.883 195.489 1.00 69.65  ? 510 TYR A O   1 
ATOM   3368 C CB  . TYR A 1 510 ? 153.172 161.186 198.449 1.00 69.65  ? 510 TYR A CB  1 
ATOM   3369 C CG  . TYR A 1 510 ? 153.507 160.360 199.667 1.00 69.65  ? 510 TYR A CG  1 
ATOM   3370 C CD1 . TYR A 1 510 ? 152.532 159.629 200.325 1.00 69.65  ? 510 TYR A CD1 1 
ATOM   3371 C CD2 . TYR A 1 510 ? 154.801 160.319 200.164 1.00 69.65  ? 510 TYR A CD2 1 
ATOM   3372 C CE1 . TYR A 1 510 ? 152.836 158.877 201.440 1.00 69.65  ? 510 TYR A CE1 1 
ATOM   3373 C CE2 . TYR A 1 510 ? 155.114 159.570 201.277 1.00 69.65  ? 510 TYR A CE2 1 
ATOM   3374 C CZ  . TYR A 1 510 ? 154.129 158.851 201.911 1.00 69.65  ? 510 TYR A CZ  1 
ATOM   3375 O OH  . TYR A 1 510 ? 154.440 158.104 203.022 1.00 69.65  ? 510 TYR A OH  1 
ATOM   3376 N N   . THR A 1 511 ? 150.376 161.571 197.035 1.00 70.01  ? 511 THR A N   1 
ATOM   3377 C CA  . THR A 1 511 ? 149.424 162.493 196.442 1.00 70.01  ? 511 THR A CA  1 
ATOM   3378 C C   . THR A 1 511 ? 149.195 163.676 197.372 1.00 70.01  ? 511 THR A C   1 
ATOM   3379 O O   . THR A 1 511 ? 149.410 163.576 198.584 1.00 70.01  ? 511 THR A O   1 
ATOM   3380 C CB  . THR A 1 511 ? 148.087 161.796 196.154 1.00 70.01  ? 511 THR A CB  1 
ATOM   3381 O OG1 . THR A 1 511 ? 147.357 161.627 197.374 1.00 70.01  ? 511 THR A OG1 1 
ATOM   3382 C CG2 . THR A 1 511 ? 148.319 160.436 195.520 1.00 70.01  ? 511 THR A CG2 1 
ATOM   3383 N N   . PRO A 1 512 ? 148.775 164.826 196.836 1.00 68.58  ? 512 PRO A N   1 
ATOM   3384 C CA  . PRO A 1 512 ? 148.560 165.996 197.702 1.00 68.58  ? 512 PRO A CA  1 
ATOM   3385 C C   . PRO A 1 512 ? 147.542 165.771 198.806 1.00 68.58  ? 512 PRO A C   1 
ATOM   3386 O O   . PRO A 1 512 ? 147.645 166.403 199.863 1.00 68.58  ? 512 PRO A O   1 
ATOM   3387 C CB  . PRO A 1 512 ? 148.087 167.072 196.717 1.00 68.58  ? 512 PRO A CB  1 
ATOM   3388 C CG  . PRO A 1 512 ? 148.664 166.664 195.417 1.00 68.58  ? 512 PRO A CG  1 
ATOM   3389 C CD  . PRO A 1 512 ? 148.655 165.168 195.409 1.00 68.58  ? 512 PRO A CD  1 
ATOM   3390 N N   . GLN A 1 513 ? 146.560 164.893 198.596 1.00 70.34  ? 513 GLN A N   1 
ATOM   3391 C CA  . GLN A 1 513 ? 145.523 164.695 199.603 1.00 70.34  ? 513 GLN A CA  1 
ATOM   3392 C C   . GLN A 1 513 ? 146.059 163.967 200.831 1.00 70.34  ? 513 GLN A C   1 
ATOM   3393 O O   . GLN A 1 513 ? 145.551 164.171 201.939 1.00 70.34  ? 513 GLN A O   1 
ATOM   3394 C CB  . GLN A 1 513 ? 144.343 163.938 198.993 1.00 70.34  ? 513 GLN A CB  1 
ATOM   3395 C CG  . GLN A 1 513 ? 143.096 163.880 199.867 1.00 70.34  ? 513 GLN A CG  1 
ATOM   3396 C CD  . GLN A 1 513 ? 143.095 162.707 200.825 1.00 70.34  ? 513 GLN A CD  1 
ATOM   3397 O OE1 . GLN A 1 513 ? 143.668 161.657 200.540 1.00 70.34  ? 513 GLN A OE1 1 
ATOM   3398 N NE2 . GLN A 1 513 ? 142.447 162.880 201.971 1.00 70.34  ? 513 GLN A NE2 1 
ATOM   3399 N N   . GLN A 1 514 ? 147.076 163.122 200.662 1.00 69.12  ? 514 GLN A N   1 
ATOM   3400 C CA  . GLN A 1 514 ? 147.647 162.389 201.785 1.00 69.12  ? 514 GLN A CA  1 
ATOM   3401 C C   . GLN A 1 514 ? 148.677 163.190 202.567 1.00 69.12  ? 514 GLN A C   1 
ATOM   3402 O O   . GLN A 1 514 ? 149.125 162.725 203.620 1.00 69.12  ? 514 GLN A O   1 
ATOM   3403 C CB  . GLN A 1 514 ? 148.308 161.096 201.301 1.00 69.12  ? 514 GLN A CB  1 
ATOM   3404 C CG  . GLN A 1 514 ? 147.542 160.339 200.242 1.00 69.12  ? 514 GLN A CG  1 
ATOM   3405 C CD  . GLN A 1 514 ? 148.191 159.013 199.906 1.00 69.12  ? 514 GLN A CD  1 
ATOM   3406 O OE1 . GLN A 1 514 ? 148.174 158.082 200.708 1.00 69.12  ? 514 GLN A OE1 1 
ATOM   3407 N NE2 . GLN A 1 514 ? 148.772 158.923 198.718 1.00 69.12  ? 514 GLN A NE2 1 
ATOM   3408 N N   . VAL A 1 515 ? 149.067 164.370 202.088 1.00 65.45  ? 515 VAL A N   1 
ATOM   3409 C CA  . VAL A 1 515 ? 150.191 165.116 202.639 1.00 65.45  ? 515 VAL A CA  1 
ATOM   3410 C C   . VAL A 1 515 ? 149.769 166.500 203.120 1.00 65.45  ? 515 VAL A C   1 
ATOM   3411 O O   . VAL A 1 515 ? 150.066 166.893 204.252 1.00 65.45  ? 515 VAL A O   1 
ATOM   3412 C CB  . VAL A 1 515 ? 151.347 165.221 201.619 1.00 65.45  ? 515 VAL A CB  1 
ATOM   3413 C CG1 . VAL A 1 515 ? 152.324 166.300 202.027 1.00 65.45  ? 515 VAL A CG1 1 
ATOM   3414 C CG2 . VAL A 1 515 ? 152.054 163.889 201.492 1.00 65.45  ? 515 VAL A CG2 1 
ATOM   3415 N N   . ALA A 1 516 ? 149.069 167.256 202.274 1.00 65.22  ? 516 ALA A N   1 
ATOM   3416 C CA  . ALA A 1 516 ? 148.812 168.664 202.545 1.00 65.22  ? 516 ALA A CA  1 
ATOM   3417 C C   . ALA A 1 516 ? 147.333 169.022 202.605 1.00 65.22  ? 516 ALA A C   1 
ATOM   3418 O O   . ALA A 1 516 ? 147.001 170.213 202.629 1.00 65.22  ? 516 ALA A O   1 
ATOM   3419 C CB  . ALA A 1 516 ? 149.507 169.534 201.494 1.00 65.22  ? 516 ALA A CB  1 
ATOM   3420 N N   . HIS A 1 517 ? 146.436 168.042 202.637 1.00 70.07  ? 517 HIS A N   1 
ATOM   3421 C CA  . HIS A 1 517 ? 145.002 168.299 202.676 1.00 70.07  ? 517 HIS A CA  1 
ATOM   3422 C C   . HIS A 1 517 ? 144.446 167.897 204.032 1.00 70.07  ? 517 HIS A C   1 
ATOM   3423 O O   . HIS A 1 517 ? 144.733 166.802 204.526 1.00 70.07  ? 517 HIS A O   1 
ATOM   3424 C CB  . HIS A 1 517 ? 144.275 167.545 201.562 1.00 70.07  ? 517 HIS A CB  1 
ATOM   3425 C CG  . HIS A 1 517 ? 144.209 168.296 200.270 1.00 70.07  ? 517 HIS A CG  1 
ATOM   3426 N ND1 . HIS A 1 517 ? 143.632 167.773 199.134 1.00 70.07  ? 517 HIS A ND1 1 
ATOM   3427 C CD2 . HIS A 1 517 ? 144.652 169.530 199.933 1.00 70.07  ? 517 HIS A CD2 1 
ATOM   3428 C CE1 . HIS A 1 517 ? 143.720 168.653 198.153 1.00 70.07  ? 517 HIS A CE1 1 
ATOM   3429 N NE2 . HIS A 1 517 ? 144.336 169.728 198.612 1.00 70.07  ? 517 HIS A NE2 1 
ATOM   3430 N N   . ALA A 1 518 ? 143.645 168.778 204.623 1.00 73.95  ? 518 ALA A N   1 
ATOM   3431 C CA  . ALA A 1 518 ? 143.102 168.545 205.951 1.00 73.95  ? 518 ALA A CA  1 
ATOM   3432 C C   . ALA A 1 518 ? 142.038 167.450 205.916 1.00 73.95  ? 518 ALA A C   1 
ATOM   3433 O O   . ALA A 1 518 ? 141.659 166.940 204.857 1.00 73.95  ? 518 ALA A O   1 
ATOM   3434 C CB  . ALA A 1 518 ? 142.516 169.835 206.521 1.00 73.95  ? 518 ALA A CB  1 
ATOM   3435 N N   . GLN A 1 519 ? 141.559 167.093 207.106 1.00 81.00  ? 519 GLN A N   1 
ATOM   3436 C CA  . GLN A 1 519 ? 140.504 166.095 207.277 1.00 81.00  ? 519 GLN A CA  1 
ATOM   3437 C C   . GLN A 1 519 ? 140.903 164.753 206.668 1.00 81.00  ? 519 GLN A C   1 
ATOM   3438 O O   . GLN A 1 519 ? 141.108 163.773 207.383 1.00 81.00  ? 519 GLN A O   1 
ATOM   3439 C CB  . GLN A 1 519 ? 139.189 166.597 206.667 1.00 81.00  ? 519 GLN A CB  1 
ATOM   3440 C CG  . GLN A 1 519 ? 137.970 165.726 206.951 1.00 81.00  ? 519 GLN A CG  1 
ATOM   3441 C CD  . GLN A 1 519 ? 137.810 164.587 205.961 1.00 81.00  ? 519 GLN A CD  1 
ATOM   3442 O OE1 . GLN A 1 519 ? 138.212 164.694 204.803 1.00 81.00  ? 519 GLN A OE1 1 
ATOM   3443 N NE2 . GLN A 1 519 ? 137.219 163.489 206.415 1.00 81.00  ? 519 GLN A NE2 1 
ATOM   3444 N N   . SER B 1 48  ? 195.033 189.059 160.740 1.00 80.73  ? 48  SER B N   1 
ATOM   3445 C CA  . SER B 1 48  ? 193.693 188.974 161.307 1.00 80.73  ? 48  SER B CA  1 
ATOM   3446 C C   . SER B 1 48  ? 192.637 188.955 160.210 1.00 80.73  ? 48  SER B C   1 
ATOM   3447 O O   . SER B 1 48  ? 191.562 188.382 160.384 1.00 80.73  ? 48  SER B O   1 
ATOM   3448 C CB  . SER B 1 48  ? 193.436 190.140 162.262 1.00 80.73  ? 48  SER B CB  1 
ATOM   3449 O OG  . SER B 1 48  ? 192.052 190.287 162.524 1.00 80.73  ? 48  SER B OG  1 
ATOM   3450 N N   . ARG B 1 49  ? 192.943 189.595 159.079 1.00 80.21  ? 49  ARG B N   1 
ATOM   3451 C CA  . ARG B 1 49  ? 192.013 189.592 157.957 1.00 80.21  ? 49  ARG B CA  1 
ATOM   3452 C C   . ARG B 1 49  ? 192.026 188.266 157.208 1.00 80.21  ? 49  ARG B C   1 
ATOM   3453 O O   . ARG B 1 49  ? 190.988 187.846 156.685 1.00 80.21  ? 49  ARG B O   1 
ATOM   3454 C CB  . ARG B 1 49  ? 192.332 190.743 156.999 1.00 80.21  ? 49  ARG B CB  1 
ATOM   3455 C CG  . ARG B 1 49  ? 193.766 190.772 156.493 1.00 80.21  ? 49  ARG B CG  1 
ATOM   3456 C CD  . ARG B 1 49  ? 193.852 190.262 155.061 1.00 80.21  ? 49  ARG B CD  1 
ATOM   3457 N NE  . ARG B 1 49  ? 195.152 190.528 154.457 1.00 80.21  ? 49  ARG B NE  1 
ATOM   3458 C CZ  . ARG B 1 49  ? 195.584 189.970 153.334 1.00 80.21  ? 49  ARG B CZ  1 
ATOM   3459 N NH1 . ARG B 1 49  ? 194.848 189.095 152.669 1.00 80.21  ? 49  ARG B NH1 1 
ATOM   3460 N NH2 . ARG B 1 49  ? 196.787 190.296 152.868 1.00 80.21  ? 49  ARG B NH2 1 
ATOM   3461 N N   . SER B 1 50  ? 193.181 187.600 157.143 1.00 73.42  ? 50  SER B N   1 
ATOM   3462 C CA  . SER B 1 50  ? 193.256 186.315 156.454 1.00 73.42  ? 50  SER B CA  1 
ATOM   3463 C C   . SER B 1 50  ? 192.389 185.268 157.141 1.00 73.42  ? 50  SER B C   1 
ATOM   3464 O O   . SER B 1 50  ? 191.703 184.486 156.473 1.00 73.42  ? 50  SER B O   1 
ATOM   3465 C CB  . SER B 1 50  ? 194.708 185.847 156.378 1.00 73.42  ? 50  SER B CB  1 
ATOM   3466 O OG  . SER B 1 50  ? 195.279 185.747 157.671 1.00 73.42  ? 50  SER B OG  1 
ATOM   3467 N N   . PHE B 1 51  ? 192.407 185.237 158.475 1.00 64.57  ? 51  PHE B N   1 
ATOM   3468 C CA  . PHE B 1 51  ? 191.584 184.282 159.211 1.00 64.57  ? 51  PHE B CA  1 
ATOM   3469 C C   . PHE B 1 51  ? 190.102 184.510 158.943 1.00 64.57  ? 51  PHE B C   1 
ATOM   3470 O O   . PHE B 1 51  ? 189.350 183.556 158.698 1.00 64.57  ? 51  PHE B O   1 
ATOM   3471 C CB  . PHE B 1 51  ? 191.888 184.389 160.705 1.00 64.57  ? 51  PHE B CB  1 
ATOM   3472 C CG  . PHE B 1 51  ? 191.135 183.409 161.555 1.00 64.57  ? 51  PHE B CG  1 
ATOM   3473 C CD1 . PHE B 1 51  ? 191.570 182.103 161.679 1.00 64.57  ? 51  PHE B CD1 1 
ATOM   3474 C CD2 . PHE B 1 51  ? 190.000 183.798 162.244 1.00 64.57  ? 51  PHE B CD2 1 
ATOM   3475 C CE1 . PHE B 1 51  ? 190.881 181.203 162.464 1.00 64.57  ? 51  PHE B CE1 1 
ATOM   3476 C CE2 . PHE B 1 51  ? 189.309 182.901 163.030 1.00 64.57  ? 51  PHE B CE2 1 
ATOM   3477 C CZ  . PHE B 1 51  ? 189.750 181.603 163.140 1.00 64.57  ? 51  PHE B CZ  1 
ATOM   3478 N N   . ILE B 1 52  ? 189.666 185.772 158.974 1.00 66.59  ? 52  ILE B N   1 
ATOM   3479 C CA  . ILE B 1 52  ? 188.262 186.088 158.726 1.00 66.59  ? 52  ILE B CA  1 
ATOM   3480 C C   . ILE B 1 52  ? 187.873 185.716 157.303 1.00 66.59  ? 52  ILE B C   1 
ATOM   3481 O O   . ILE B 1 52  ? 186.811 185.124 157.067 1.00 66.59  ? 52  ILE B O   1 
ATOM   3482 C CB  . ILE B 1 52  ? 187.990 187.574 159.019 1.00 66.59  ? 52  ILE B CB  1 
ATOM   3483 C CG1 . ILE B 1 52  ? 188.014 187.831 160.525 1.00 66.59  ? 52  ILE B CG1 1 
ATOM   3484 C CG2 . ILE B 1 52  ? 186.661 188.004 158.429 1.00 66.59  ? 52  ILE B CG2 1 
ATOM   3485 C CD1 . ILE B 1 52  ? 187.865 189.286 160.894 1.00 66.59  ? 52  ILE B CD1 1 
ATOM   3486 N N   . ALA B 1 53  ? 188.723 186.052 156.331 1.00 63.06  ? 53  ALA B N   1 
ATOM   3487 C CA  . ALA B 1 53  ? 188.426 185.705 154.947 1.00 63.06  ? 53  ALA B CA  1 
ATOM   3488 C C   . ALA B 1 53  ? 188.312 184.198 154.773 1.00 63.06  ? 53  ALA B C   1 
ATOM   3489 O O   . ALA B 1 53  ? 187.387 183.711 154.112 1.00 63.06  ? 53  ALA B O   1 
ATOM   3490 C CB  . ALA B 1 53  ? 189.499 186.273 154.021 1.00 63.06  ? 53  ALA B CB  1 
ATOM   3491 N N   . ALA B 1 54  ? 189.228 183.442 155.380 1.00 62.36  ? 54  ALA B N   1 
ATOM   3492 C CA  . ALA B 1 54  ? 189.195 181.990 155.254 1.00 62.36  ? 54  ALA B CA  1 
ATOM   3493 C C   . ALA B 1 54  ? 187.923 181.411 155.859 1.00 62.36  ? 54  ALA B C   1 
ATOM   3494 O O   . ALA B 1 54  ? 187.254 180.576 155.238 1.00 62.36  ? 54  ALA B O   1 
ATOM   3495 C CB  . ALA B 1 54  ? 190.433 181.380 155.909 1.00 62.36  ? 54  ALA B CB  1 
ATOM   3496 N N   . VAL B 1 55  ? 187.562 181.848 157.069 1.00 59.51  ? 55  VAL B N   1 
ATOM   3497 C CA  . VAL B 1 55  ? 186.402 181.251 157.724 1.00 59.51  ? 55  VAL B CA  1 
ATOM   3498 C C   . VAL B 1 55  ? 185.117 181.621 156.988 1.00 59.51  ? 55  VAL B C   1 
ATOM   3499 O O   . VAL B 1 55  ? 184.220 180.783 156.828 1.00 59.51  ? 55  VAL B O   1 
ATOM   3500 C CB  . VAL B 1 55  ? 186.348 181.633 159.216 1.00 59.51  ? 55  VAL B CB  1 
ATOM   3501 C CG1 . VAL B 1 55  ? 187.574 181.106 159.936 1.00 59.51  ? 55  VAL B CG1 1 
ATOM   3502 C CG2 . VAL B 1 55  ? 186.224 183.129 159.406 1.00 59.51  ? 55  VAL B CG2 1 
ATOM   3503 N N   . ILE B 1 56  ? 185.013 182.862 156.503 1.00 59.30  ? 56  ILE B N   1 
ATOM   3504 C CA  . ILE B 1 56  ? 183.824 183.255 155.752 1.00 59.30  ? 56  ILE B CA  1 
ATOM   3505 C C   . ILE B 1 56  ? 183.729 182.470 154.448 1.00 59.30  ? 56  ILE B C   1 
ATOM   3506 O O   . ILE B 1 56  ? 182.652 181.986 154.076 1.00 59.30  ? 56  ILE B O   1 
ATOM   3507 C CB  . ILE B 1 56  ? 183.825 184.774 155.504 1.00 59.30  ? 56  ILE B CB  1 
ATOM   3508 C CG1 . ILE B 1 56  ? 183.712 185.533 156.826 1.00 59.30  ? 56  ILE B CG1 1 
ATOM   3509 C CG2 . ILE B 1 56  ? 182.691 185.164 154.578 1.00 59.30  ? 56  ILE B CG2 1 
ATOM   3510 C CD1 . ILE B 1 56  ? 182.325 185.549 157.407 1.00 59.30  ? 56  ILE B CD1 1 
ATOM   3511 N N   . ALA B 1 57  ? 184.851 182.323 153.737 1.00 57.53  ? 57  ALA B N   1 
ATOM   3512 C CA  . ALA B 1 57  ? 184.835 181.587 152.479 1.00 57.53  ? 57  ALA B CA  1 
ATOM   3513 C C   . ALA B 1 57  ? 184.438 180.136 152.694 1.00 57.53  ? 57  ALA B C   1 
ATOM   3514 O O   . ALA B 1 57  ? 183.678 179.570 151.902 1.00 57.53  ? 57  ALA B O   1 
ATOM   3515 C CB  . ALA B 1 57  ? 186.203 181.670 151.805 1.00 57.53  ? 57  ALA B CB  1 
ATOM   3516 N N   . ILE B 1 58  ? 184.946 179.514 153.759 1.00 54.50  ? 58  ILE B N   1 
ATOM   3517 C CA  . ILE B 1 58  ? 184.614 178.117 154.015 1.00 54.50  ? 58  ILE B CA  1 
ATOM   3518 C C   . ILE B 1 58  ? 183.147 177.973 154.403 1.00 54.50  ? 58  ILE B C   1 
ATOM   3519 O O   . ILE B 1 58  ? 182.456 177.060 153.936 1.00 54.50  ? 58  ILE B O   1 
ATOM   3520 C CB  . ILE B 1 58  ? 185.547 177.531 155.086 1.00 54.50  ? 58  ILE B CB  1 
ATOM   3521 C CG1 . ILE B 1 58  ? 186.991 177.533 154.590 1.00 54.50  ? 58  ILE B CG1 1 
ATOM   3522 C CG2 . ILE B 1 58  ? 185.134 176.125 155.411 1.00 54.50  ? 58  ILE B CG2 1 
ATOM   3523 C CD1 . ILE B 1 58  ? 187.998 177.186 155.654 1.00 54.50  ? 58  ILE B CD1 1 
ATOM   3524 N N   . GLY B 1 59  ? 182.640 178.866 155.250 1.00 54.92  ? 59  GLY B N   1 
ATOM   3525 C CA  . GLY B 1 59  ? 181.261 178.743 155.675 1.00 54.92  ? 59  GLY B CA  1 
ATOM   3526 C C   . GLY B 1 59  ? 180.216 179.312 154.743 1.00 54.92  ? 59  GLY B C   1 
ATOM   3527 O O   . GLY B 1 59  ? 179.026 179.226 155.053 1.00 54.92  ? 59  GLY B O   1 
ATOM   3528 N N   . GLY B 1 60  ? 180.619 179.903 153.616 1.00 55.33  ? 60  GLY B N   1 
ATOM   3529 C CA  . GLY B 1 60  ? 179.648 180.515 152.721 1.00 55.33  ? 60  GLY B CA  1 
ATOM   3530 C C   . GLY B 1 60  ? 178.618 179.563 152.138 1.00 55.33  ? 60  GLY B C   1 
ATOM   3531 O O   . GLY B 1 60  ? 177.471 179.959 151.901 1.00 55.33  ? 60  GLY B O   1 
ATOM   3532 N N   . MET B 1 61  ? 179.004 178.314 151.876 1.00 52.84  ? 61  MET B N   1 
ATOM   3533 C CA  . MET B 1 61  ? 178.083 177.407 151.195 1.00 52.84  ? 61  MET B CA  1 
ATOM   3534 C C   . MET B 1 61  ? 176.912 177.016 152.089 1.00 52.84  ? 61  MET B C   1 
ATOM   3535 O O   . MET B 1 61  ? 175.799 176.800 151.597 1.00 52.84  ? 61  MET B O   1 
ATOM   3536 C CB  . MET B 1 61  ? 178.819 176.165 150.701 1.00 52.84  ? 61  MET B CB  1 
ATOM   3537 C CG  . MET B 1 61  ? 177.904 175.181 149.997 1.00 52.84  ? 61  MET B CG  1 
ATOM   3538 S SD  . MET B 1 61  ? 177.807 175.508 148.229 1.00 52.84  ? 61  MET B SD  1 
ATOM   3539 C CE  . MET B 1 61  ? 176.048 175.362 147.957 1.00 52.84  ? 61  MET B CE  1 
ATOM   3540 N N   . GLN B 1 62  ? 177.136 176.917 153.399 1.00 53.82  ? 62  GLN B N   1 
ATOM   3541 C CA  . GLN B 1 62  ? 176.029 176.652 154.312 1.00 53.82  ? 62  GLN B CA  1 
ATOM   3542 C C   . GLN B 1 62  ? 174.987 177.759 154.229 1.00 53.82  ? 62  GLN B C   1 
ATOM   3543 O O   . GLN B 1 62  ? 173.781 177.494 154.116 1.00 53.82  ? 62  GLN B O   1 
ATOM   3544 C CB  . GLN B 1 62  ? 176.553 176.512 155.740 1.00 53.82  ? 62  GLN B CB  1 
ATOM   3545 C CG  . GLN B 1 62  ? 177.438 175.306 155.956 1.00 53.82  ? 62  GLN B CG  1 
ATOM   3546 C CD  . GLN B 1 62  ? 176.644 174.038 156.165 1.00 53.82  ? 62  GLN B CD  1 
ATOM   3547 O OE1 . GLN B 1 62  ? 176.696 173.118 155.351 1.00 53.82  ? 62  GLN B OE1 1 
ATOM   3548 N NE2 . GLN B 1 62  ? 175.899 173.982 157.260 1.00 53.82  ? 62  GLN B NE2 1 
ATOM   3549 N N   . LEU B 1 63  ? 175.445 179.012 154.259 1.00 54.88  ? 63  LEU B N   1 
ATOM   3550 C CA  . LEU B 1 63  ? 174.546 180.150 154.119 1.00 54.88  ? 63  LEU B CA  1 
ATOM   3551 C C   . LEU B 1 63  ? 173.802 180.094 152.794 1.00 54.88  ? 63  LEU B C   1 
ATOM   3552 O O   . LEU B 1 63  ? 172.579 180.266 152.747 1.00 54.88  ? 63  LEU B O   1 
ATOM   3553 C CB  . LEU B 1 63  ? 175.343 181.450 154.235 1.00 54.88  ? 63  LEU B CB  1 
ATOM   3554 C CG  . LEU B 1 63  ? 174.584 182.773 154.324 1.00 54.88  ? 63  LEU B CG  1 
ATOM   3555 C CD1 . LEU B 1 63  ? 175.242 183.679 155.343 1.00 54.88  ? 63  LEU B CD1 1 
ATOM   3556 C CD2 . LEU B 1 63  ? 174.526 183.457 152.974 1.00 54.88  ? 63  LEU B CD2 1 
ATOM   3557 N N   . LEU B 1 64  ? 174.528 179.836 151.704 1.00 54.16  ? 64  LEU B N   1 
ATOM   3558 C CA  . LEU B 1 64  ? 173.904 179.823 150.384 1.00 54.16  ? 64  LEU B CA  1 
ATOM   3559 C C   . LEU B 1 64  ? 172.812 178.765 150.301 1.00 54.16  ? 64  LEU B C   1 
ATOM   3560 O O   . LEU B 1 64  ? 171.677 179.056 149.904 1.00 54.16  ? 64  LEU B O   1 
ATOM   3561 C CB  . LEU B 1 64  ? 174.959 179.587 149.306 1.00 54.16  ? 64  LEU B CB  1 
ATOM   3562 C CG  . LEU B 1 64  ? 175.709 180.812 148.783 1.00 54.16  ? 64  LEU B CG  1 
ATOM   3563 C CD1 . LEU B 1 64  ? 176.756 180.396 147.768 1.00 54.16  ? 64  LEU B CD1 1 
ATOM   3564 C CD2 . LEU B 1 64  ? 174.742 181.813 148.181 1.00 54.16  ? 64  LEU B CD2 1 
ATOM   3565 N N   . ALA B 1 65  ? 173.137 177.528 150.685 1.00 54.84  ? 65  ALA B N   1 
ATOM   3566 C CA  . ALA B 1 65  ? 172.175 176.437 150.573 1.00 54.84  ? 65  ALA B CA  1 
ATOM   3567 C C   . ALA B 1 65  ? 170.961 176.666 151.463 1.00 54.84  ? 65  ALA B C   1 
ATOM   3568 O O   . ALA B 1 65  ? 169.817 176.481 151.025 1.00 54.84  ? 65  ALA B O   1 
ATOM   3569 C CB  . ALA B 1 65  ? 172.849 175.112 150.919 1.00 54.84  ? 65  ALA B CB  1 
ATOM   3570 N N   . THR B 1 66  ? 171.182 177.073 152.718 1.00 55.04  ? 66  THR B N   1 
ATOM   3571 C CA  . THR B 1 66  ? 170.056 177.247 153.628 1.00 55.04  ? 66  THR B CA  1 
ATOM   3572 C C   . THR B 1 66  ? 169.155 178.394 153.186 1.00 55.04  ? 66  THR B C   1 
ATOM   3573 O O   . THR B 1 66  ? 167.921 178.271 153.212 1.00 55.04  ? 66  THR B O   1 
ATOM   3574 C CB  . THR B 1 66  ? 170.565 177.480 155.046 1.00 55.04  ? 66  THR B CB  1 
ATOM   3575 O OG1 . THR B 1 66  ? 171.436 176.408 155.422 1.00 55.04  ? 66  THR B OG1 1 
ATOM   3576 C CG2 . THR B 1 66  ? 169.406 177.509 156.003 1.00 55.04  ? 66  THR B CG2 1 
ATOM   3577 N N   . MET B 1 67  ? 169.749 179.518 152.773 1.00 58.67  ? 67  MET B N   1 
ATOM   3578 C CA  . MET B 1 67  ? 168.952 180.641 152.302 1.00 58.67  ? 67  MET B CA  1 
ATOM   3579 C C   . MET B 1 67  ? 168.167 180.272 151.054 1.00 58.67  ? 67  MET B C   1 
ATOM   3580 O O   . MET B 1 67  ? 166.998 180.649 150.916 1.00 58.67  ? 67  MET B O   1 
ATOM   3581 C CB  . MET B 1 67  ? 169.855 181.844 152.038 1.00 58.67  ? 67  MET B CB  1 
ATOM   3582 C CG  . MET B 1 67  ? 169.122 183.089 151.591 1.00 58.67  ? 67  MET B CG  1 
ATOM   3583 S SD  . MET B 1 67  ? 170.254 184.462 151.330 1.00 58.67  ? 67  MET B SD  1 
ATOM   3584 C CE  . MET B 1 67  ? 171.070 183.925 149.833 1.00 58.67  ? 67  MET B CE  1 
ATOM   3585 N N   . ASP B 1 68  ? 168.788 179.530 150.132 1.00 59.51  ? 68  ASP B N   1 
ATOM   3586 C CA  . ASP B 1 68  ? 168.073 179.112 148.933 1.00 59.51  ? 68  ASP B CA  1 
ATOM   3587 C C   . ASP B 1 68  ? 166.889 178.222 149.280 1.00 59.51  ? 68  ASP B C   1 
ATOM   3588 O O   . ASP B 1 68  ? 165.802 178.378 148.712 1.00 59.51  ? 68  ASP B O   1 
ATOM   3589 C CB  . ASP B 1 68  ? 169.020 178.388 147.980 1.00 59.51  ? 68  ASP B CB  1 
ATOM   3590 C CG  . ASP B 1 68  ? 168.282 177.632 146.898 1.00 59.51  ? 68  ASP B CG  1 
ATOM   3591 O OD1 . ASP B 1 68  ? 167.930 178.253 145.873 1.00 59.51  ? 68  ASP B OD1 1 
ATOM   3592 O OD2 . ASP B 1 68  ? 168.048 176.418 147.073 1.00 59.51  ? 68  ASP B OD2 1 
ATOM   3593 N N   . SER B 1 69  ? 167.076 177.283 150.210 1.00 57.49  ? 69  SER B N   1 
ATOM   3594 C CA  . SER B 1 69  ? 165.975 176.407 150.600 1.00 57.49  ? 69  SER B CA  1 
ATOM   3595 C C   . SER B 1 69  ? 164.829 177.203 151.215 1.00 57.49  ? 69  SER B C   1 
ATOM   3596 O O   . SER B 1 69  ? 163.656 176.993 150.877 1.00 57.49  ? 69  SER B O   1 
ATOM   3597 C CB  . SER B 1 69  ? 166.474 175.341 151.573 1.00 57.49  ? 69  SER B CB  1 
ATOM   3598 O OG  . SER B 1 69  ? 167.597 174.659 151.045 1.00 57.49  ? 69  SER B OG  1 
ATOM   3599 N N   . THR B 1 70  ? 165.152 178.134 152.117 1.00 57.76  ? 70  THR B N   1 
ATOM   3600 C CA  . THR B 1 70  ? 164.105 178.927 152.758 1.00 57.76  ? 70  THR B CA  1 
ATOM   3601 C C   . THR B 1 70  ? 163.354 179.784 151.744 1.00 57.76  ? 70  THR B C   1 
ATOM   3602 O O   . THR B 1 70  ? 162.119 179.871 151.785 1.00 57.76  ? 70  THR B O   1 
ATOM   3603 C CB  . THR B 1 70  ? 164.705 179.801 153.857 1.00 57.76  ? 70  THR B CB  1 
ATOM   3604 O OG1 . THR B 1 70  ? 165.571 179.009 154.678 1.00 57.76  ? 70  THR B OG1 1 
ATOM   3605 C CG2 . THR B 1 70  ? 163.609 180.389 154.721 1.00 57.76  ? 70  THR B CG2 1 
ATOM   3606 N N   . VAL B 1 71  ? 164.080 180.421 150.821 1.00 58.44  ? 71  VAL B N   1 
ATOM   3607 C CA  . VAL B 1 71  ? 163.431 181.251 149.809 1.00 58.44  ? 71  VAL B CA  1 
ATOM   3608 C C   . VAL B 1 71  ? 162.545 180.407 148.905 1.00 58.44  ? 71  VAL B C   1 
ATOM   3609 O O   . VAL B 1 71  ? 161.421 180.801 148.571 1.00 58.44  ? 71  VAL B O   1 
ATOM   3610 C CB  . VAL B 1 71  ? 164.479 182.034 149.002 1.00 58.44  ? 71  VAL B CB  1 
ATOM   3611 C CG1 . VAL B 1 71  ? 163.810 182.786 147.882 1.00 58.44  ? 71  VAL B CG1 1 
ATOM   3612 C CG2 . VAL B 1 71  ? 165.213 183.005 149.901 1.00 58.44  ? 71  VAL B CG2 1 
ATOM   3613 N N   . ALA B 1 72  ? 163.031 179.234 148.491 1.00 60.11  ? 72  ALA B N   1 
ATOM   3614 C CA  . ALA B 1 72  ? 162.225 178.366 147.639 1.00 60.11  ? 72  ALA B CA  1 
ATOM   3615 C C   . ALA B 1 72  ? 160.954 177.929 148.351 1.00 60.11  ? 72  ALA B C   1 
ATOM   3616 O O   . ALA B 1 72  ? 159.895 177.806 147.726 1.00 60.11  ? 72  ALA B O   1 
ATOM   3617 C CB  . ALA B 1 72  ? 163.042 177.153 147.201 1.00 60.11  ? 72  ALA B CB  1 
ATOM   3618 N N   . ILE B 1 73  ? 161.040 177.681 149.659 1.00 62.34  ? 73  ILE B N   1 
ATOM   3619 C CA  . ILE B 1 73  ? 159.841 177.339 150.420 1.00 62.34  ? 73  ILE B CA  1 
ATOM   3620 C C   . ILE B 1 73  ? 158.871 178.515 150.458 1.00 62.34  ? 73  ILE B C   1 
ATOM   3621 O O   . ILE B 1 73  ? 157.658 178.341 150.290 1.00 62.34  ? 73  ILE B O   1 
ATOM   3622 C CB  . ILE B 1 73  ? 160.224 176.869 151.834 1.00 62.34  ? 73  ILE B CB  1 
ATOM   3623 C CG1 . ILE B 1 73  ? 160.772 175.444 151.785 1.00 62.34  ? 73  ILE B CG1 1 
ATOM   3624 C CG2 . ILE B 1 73  ? 159.029 176.946 152.769 1.00 62.34  ? 73  ILE B CG2 1 
ATOM   3625 C CD1 . ILE B 1 73  ? 159.765 174.426 151.310 1.00 62.34  ? 73  ILE B CD1 1 
ATOM   3626 N N   . VAL B 1 74  ? 159.384 179.729 150.675 1.00 64.38  ? 74  VAL B N   1 
ATOM   3627 C CA  . VAL B 1 74  ? 158.505 180.888 150.836 1.00 64.38  ? 74  VAL B CA  1 
ATOM   3628 C C   . VAL B 1 74  ? 157.764 181.207 149.539 1.00 64.38  ? 74  VAL B C   1 
ATOM   3629 O O   . VAL B 1 74  ? 156.554 181.461 149.550 1.00 64.38  ? 74  VAL B O   1 
ATOM   3630 C CB  . VAL B 1 74  ? 159.309 182.100 151.339 1.00 64.38  ? 74  VAL B CB  1 
ATOM   3631 C CG1 . VAL B 1 74  ? 158.502 183.374 151.182 1.00 64.38  ? 74  VAL B CG1 1 
ATOM   3632 C CG2 . VAL B 1 74  ? 159.708 181.904 152.789 1.00 64.38  ? 74  VAL B CG2 1 
ATOM   3633 N N   . ALA B 1 75  ? 158.467 181.196 148.406 1.00 66.94  ? 75  ALA B N   1 
ATOM   3634 C CA  . ALA B 1 75  ? 157.928 181.690 147.145 1.00 66.94  ? 75  ALA B CA  1 
ATOM   3635 C C   . ALA B 1 75  ? 157.283 180.602 146.291 1.00 66.94  ? 75  ALA B C   1 
ATOM   3636 O O   . ALA B 1 75  ? 157.165 180.777 145.075 1.00 66.94  ? 75  ALA B O   1 
ATOM   3637 C CB  . ALA B 1 75  ? 159.027 182.390 146.346 1.00 66.94  ? 75  ALA B CB  1 
ATOM   3638 N N   . LEU B 1 76  ? 156.875 179.483 146.895 1.00 72.47  ? 76  LEU B N   1 
ATOM   3639 C CA  . LEU B 1 76  ? 156.270 178.406 146.110 1.00 72.47  ? 76  LEU B CA  1 
ATOM   3640 C C   . LEU B 1 76  ? 154.919 178.783 145.507 1.00 72.47  ? 76  LEU B C   1 
ATOM   3641 O O   . LEU B 1 76  ? 154.707 178.511 144.310 1.00 72.47  ? 76  LEU B O   1 
ATOM   3642 C CB  . LEU B 1 76  ? 156.173 177.140 146.966 1.00 72.47  ? 76  LEU B CB  1 
ATOM   3643 C CG  . LEU B 1 76  ? 156.236 175.810 146.219 1.00 72.47  ? 76  LEU B CG  1 
ATOM   3644 C CD1 . LEU B 1 76  ? 157.408 175.792 145.257 1.00 72.47  ? 76  LEU B CD1 1 
ATOM   3645 C CD2 . LEU B 1 76  ? 156.332 174.658 147.204 1.00 72.47  ? 76  LEU B CD2 1 
ATOM   3646 N N   . PRO B 1 77  ? 153.961 179.361 146.251 1.00 74.18  ? 77  PRO B N   1 
ATOM   3647 C CA  . PRO B 1 77  ? 152.650 179.644 145.637 1.00 74.18  ? 77  PRO B CA  1 
ATOM   3648 C C   . PRO B 1 77  ? 152.715 180.570 144.436 1.00 74.18  ? 77  PRO B C   1 
ATOM   3649 O O   . PRO B 1 77  ? 151.958 180.380 143.477 1.00 74.18  ? 77  PRO B O   1 
ATOM   3650 C CB  . PRO B 1 77  ? 151.855 180.268 146.791 1.00 74.18  ? 77  PRO B CB  1 
ATOM   3651 C CG  . PRO B 1 77  ? 152.495 179.737 148.012 1.00 74.18  ? 77  PRO B CG  1 
ATOM   3652 C CD  . PRO B 1 77  ? 153.952 179.678 147.690 1.00 74.18  ? 77  PRO B CD  1 
ATOM   3653 N N   . LYS B 1 78  ? 153.595 181.573 144.458 1.00 74.11  ? 78  LYS B N   1 
ATOM   3654 C CA  . LYS B 1 78  ? 153.722 182.460 143.307 1.00 74.11  ? 78  LYS B CA  1 
ATOM   3655 C C   . LYS B 1 78  ? 154.237 181.706 142.089 1.00 74.11  ? 78  LYS B C   1 
ATOM   3656 O O   . LYS B 1 78  ? 153.785 181.949 140.962 1.00 74.11  ? 78  LYS B O   1 
ATOM   3657 C CB  . LYS B 1 78  ? 154.641 183.630 143.650 1.00 74.11  ? 78  LYS B CB  1 
ATOM   3658 C CG  . LYS B 1 78  ? 154.206 184.408 144.878 1.00 74.11  ? 78  LYS B CG  1 
ATOM   3659 C CD  . LYS B 1 78  ? 155.342 185.249 145.433 1.00 74.11  ? 78  LYS B CD  1 
ATOM   3660 C CE  . LYS B 1 78  ? 155.710 186.372 144.481 1.00 74.11  ? 78  LYS B CE  1 
ATOM   3661 N NZ  . LYS B 1 78  ? 154.797 187.539 144.619 1.00 74.11  ? 78  LYS B NZ  1 
ATOM   3662 N N   . ILE B 1 79  ? 155.184 180.789 142.297 1.00 74.06  ? 79  ILE B N   1 
ATOM   3663 C CA  . ILE B 1 79  ? 155.662 179.944 141.207 1.00 74.06  ? 79  ILE B CA  1 
ATOM   3664 C C   . ILE B 1 79  ? 154.512 179.124 140.643 1.00 74.06  ? 79  ILE B C   1 
ATOM   3665 O O   . ILE B 1 79  ? 154.341 179.015 139.423 1.00 74.06  ? 79  ILE B O   1 
ATOM   3666 C CB  . ILE B 1 79  ? 156.810 179.039 141.690 1.00 74.06  ? 79  ILE B CB  1 
ATOM   3667 C CG1 . ILE B 1 79  ? 158.028 179.872 142.082 1.00 74.06  ? 79  ILE B CG1 1 
ATOM   3668 C CG2 . ILE B 1 79  ? 157.185 178.037 140.615 1.00 74.06  ? 79  ILE B CG2 1 
ATOM   3669 C CD1 . ILE B 1 79  ? 159.222 179.043 142.494 1.00 74.06  ? 79  ILE B CD1 1 
ATOM   3670 N N   . GLN B 1 80  ? 153.699 178.542 141.529 1.00 80.56  ? 80  GLN B N   1 
ATOM   3671 C CA  . GLN B 1 80  ? 152.570 177.740 141.069 1.00 80.56  ? 80  GLN B CA  1 
ATOM   3672 C C   . GLN B 1 80  ? 151.590 178.574 140.254 1.00 80.56  ? 80  GLN B C   1 
ATOM   3673 O O   . GLN B 1 80  ? 151.117 178.133 139.200 1.00 80.56  ? 80  GLN B O   1 
ATOM   3674 C CB  . GLN B 1 80  ? 151.859 177.097 142.258 1.00 80.56  ? 80  GLN B CB  1 
ATOM   3675 C CG  . GLN B 1 80  ? 150.475 176.567 141.923 1.00 80.56  ? 80  GLN B CG  1 
ATOM   3676 C CD  . GLN B 1 80  ? 149.907 175.685 143.013 1.00 80.56  ? 80  GLN B CD  1 
ATOM   3677 O OE1 . GLN B 1 80  ? 149.772 176.106 144.160 1.00 80.56  ? 80  GLN B OE1 1 
ATOM   3678 N NE2 . GLN B 1 80  ? 149.568 174.452 142.658 1.00 80.56  ? 80  GLN B NE2 1 
ATOM   3679 N N   . ASN B 1 81  ? 151.275 179.784 140.720 1.00 79.91  ? 81  ASN B N   1 
ATOM   3680 C CA  . ASN B 1 81  ? 150.310 180.614 140.004 1.00 79.91  ? 81  ASN B CA  1 
ATOM   3681 C C   . ASN B 1 81  ? 150.845 181.052 138.646 1.00 79.91  ? 81  ASN B C   1 
ATOM   3682 O O   . ASN B 1 81  ? 150.146 180.939 137.633 1.00 79.91  ? 81  ASN B O   1 
ATOM   3683 C CB  . ASN B 1 81  ? 149.908 181.832 140.839 1.00 79.91  ? 81  ASN B CB  1 
ATOM   3684 C CG  . ASN B 1 81  ? 149.183 181.456 142.116 1.00 79.91  ? 81  ASN B CG  1 
ATOM   3685 O OD1 . ASN B 1 81  ? 149.677 181.684 143.218 1.00 79.91  ? 81  ASN B OD1 1 
ATOM   3686 N ND2 . ASN B 1 81  ? 147.997 180.879 141.971 1.00 79.91  ? 81  ASN B ND2 1 
ATOM   3687 N N   . GLU B 1 82  ? 152.079 181.561 138.595 1.00 79.28  ? 82  GLU B N   1 
ATOM   3688 C CA  . GLU B 1 82  ? 152.575 182.095 137.330 1.00 79.28  ? 82  GLU B CA  1 
ATOM   3689 C C   . GLU B 1 82  ? 152.861 180.980 136.331 1.00 79.28  ? 82  GLU B C   1 
ATOM   3690 O O   . GLU B 1 82  ? 152.459 181.062 135.165 1.00 79.28  ? 82  GLU B O   1 
ATOM   3691 C CB  . GLU B 1 82  ? 153.826 182.946 137.548 1.00 79.28  ? 82  GLU B CB  1 
ATOM   3692 C CG  . GLU B 1 82  ? 154.641 183.126 136.271 1.00 79.28  ? 82  GLU B CG  1 
ATOM   3693 C CD  . GLU B 1 82  ? 155.891 183.956 136.470 1.00 79.28  ? 82  GLU B CD  1 
ATOM   3694 O OE1 . GLU B 1 82  ? 156.708 183.598 137.337 1.00 79.28  ? 82  GLU B OE1 1 
ATOM   3695 O OE2 . GLU B 1 82  ? 156.060 184.967 135.754 1.00 79.28  ? 82  GLU B OE2 1 
ATOM   3696 N N   . LEU B 1 83  ? 153.548 179.924 136.768 1.00 80.78  ? 83  LEU B N   1 
ATOM   3697 C CA  . LEU B 1 83  ? 153.937 178.856 135.858 1.00 80.78  ? 83  LEU B CA  1 
ATOM   3698 C C   . LEU B 1 83  ? 152.828 177.840 135.617 1.00 80.78  ? 83  LEU B C   1 
ATOM   3699 O O   . LEU B 1 83  ? 152.995 176.965 134.761 1.00 80.78  ? 83  LEU B O   1 
ATOM   3700 C CB  . LEU B 1 83  ? 155.179 178.142 136.394 1.00 80.78  ? 83  LEU B CB  1 
ATOM   3701 C CG  . LEU B 1 83  ? 156.521 178.707 135.932 1.00 80.78  ? 83  LEU B CG  1 
ATOM   3702 C CD1 . LEU B 1 83  ? 157.663 177.820 136.393 1.00 80.78  ? 83  LEU B CD1 1 
ATOM   3703 C CD2 . LEU B 1 83  ? 156.538 178.868 134.423 1.00 80.78  ? 83  LEU B CD2 1 
ATOM   3704 N N   . SER B 1 84  ? 151.712 177.937 136.341 1.00 83.60  ? 84  SER B N   1 
ATOM   3705 C CA  . SER B 1 84  ? 150.562 177.047 136.176 1.00 83.60  ? 84  SER B CA  1 
ATOM   3706 C C   . SER B 1 84  ? 150.964 175.583 136.371 1.00 83.60  ? 84  SER B C   1 
ATOM   3707 O O   . SER B 1 84  ? 150.862 174.752 135.467 1.00 83.60  ? 84  SER B O   1 
ATOM   3708 C CB  . SER B 1 84  ? 149.889 177.263 134.816 1.00 83.60  ? 84  SER B CB  1 
ATOM   3709 O OG  . SER B 1 84  ? 150.720 176.826 133.755 1.00 83.60  ? 84  SER B OG  1 
ATOM   3710 N N   . LEU B 1 85  ? 151.424 175.282 137.580 1.00 85.11  ? 85  LEU B N   1 
ATOM   3711 C CA  . LEU B 1 85  ? 151.804 173.932 137.961 1.00 85.11  ? 85  LEU B CA  1 
ATOM   3712 C C   . LEU B 1 85  ? 150.726 173.306 138.837 1.00 85.11  ? 85  LEU B C   1 
ATOM   3713 O O   . LEU B 1 85  ? 150.027 173.996 139.582 1.00 85.11  ? 85  LEU B O   1 
ATOM   3714 C CB  . LEU B 1 85  ? 153.138 173.925 138.709 1.00 85.11  ? 85  LEU B CB  1 
ATOM   3715 C CG  . LEU B 1 85  ? 154.236 174.848 138.184 1.00 85.11  ? 85  LEU B CG  1 
ATOM   3716 C CD1 . LEU B 1 85  ? 155.430 174.836 139.124 1.00 85.11  ? 85  LEU B CD1 1 
ATOM   3717 C CD2 . LEU B 1 85  ? 154.652 174.444 136.781 1.00 85.11  ? 85  LEU B CD2 1 
ATOM   3718 N N   . SER B 1 86  ? 150.597 171.987 138.736 1.00 90.49  ? 86  SER B N   1 
ATOM   3719 C CA  . SER B 1 86  ? 149.673 171.241 139.578 1.00 90.49  ? 86  SER B CA  1 
ATOM   3720 C C   . SER B 1 86  ? 150.340 170.951 140.922 1.00 90.49  ? 86  SER B C   1 
ATOM   3721 O O   . SER B 1 86  ? 151.439 171.429 141.214 1.00 90.49  ? 86  SER B O   1 
ATOM   3722 C CB  . SER B 1 86  ? 149.225 169.967 138.870 1.00 90.49  ? 86  SER B CB  1 
ATOM   3723 O OG  . SER B 1 86  ? 150.260 169.000 138.863 1.00 90.49  ? 86  SER B OG  1 
ATOM   3724 N N   . ASP B 1 87  ? 149.671 170.163 141.766 1.00 94.15  ? 87  ASP B N   1 
ATOM   3725 C CA  . ASP B 1 87  ? 150.253 169.805 143.057 1.00 94.15  ? 87  ASP B CA  1 
ATOM   3726 C C   . ASP B 1 87  ? 151.499 168.946 142.884 1.00 94.15  ? 87  ASP B C   1 
ATOM   3727 O O   . ASP B 1 87  ? 152.485 169.116 143.614 1.00 94.15  ? 87  ASP B O   1 
ATOM   3728 C CB  . ASP B 1 87  ? 149.216 169.083 143.916 1.00 94.15  ? 87  ASP B CB  1 
ATOM   3729 C CG  . ASP B 1 87  ? 148.102 170.002 144.376 1.00 94.15  ? 87  ASP B CG  1 
ATOM   3730 O OD1 . ASP B 1 87  ? 148.405 171.127 144.825 1.00 94.15  ? 87  ASP B OD1 1 
ATOM   3731 O OD2 . ASP B 1 87  ? 146.923 169.600 144.287 1.00 94.15  ? 87  ASP B OD2 1 
ATOM   3732 N N   . ALA B 1 88  ? 151.474 168.019 141.924 1.00 92.07  ? 88  ALA B N   1 
ATOM   3733 C CA  . ALA B 1 88  ? 152.633 167.167 141.682 1.00 92.07  ? 88  ALA B CA  1 
ATOM   3734 C C   . ALA B 1 88  ? 153.839 167.992 141.257 1.00 92.07  ? 88  ALA B C   1 
ATOM   3735 O O   . ALA B 1 88  ? 154.952 167.785 141.752 1.00 92.07  ? 88  ALA B O   1 
ATOM   3736 C CB  . ALA B 1 88  ? 152.297 166.114 140.626 1.00 92.07  ? 88  ALA B CB  1 
ATOM   3737 N N   . GLY B 1 89  ? 153.635 168.943 140.344 1.00 87.70  ? 89  GLY B N   1 
ATOM   3738 C CA  . GLY B 1 89  ? 154.732 169.805 139.933 1.00 87.70  ? 89  GLY B CA  1 
ATOM   3739 C C   . GLY B 1 89  ? 155.233 170.685 141.061 1.00 87.70  ? 89  GLY B C   1 
ATOM   3740 O O   . GLY B 1 89  ? 156.439 170.920 141.191 1.00 87.70  ? 89  GLY B O   1 
ATOM   3741 N N   . ARG B 1 90  ? 154.317 171.183 141.893 1.00 86.23  ? 90  ARG B N   1 
ATOM   3742 C CA  . ARG B 1 90  ? 154.720 172.006 143.027 1.00 86.23  ? 90  ARG B CA  1 
ATOM   3743 C C   . ARG B 1 90  ? 155.584 171.216 144.001 1.00 86.23  ? 90  ARG B C   1 
ATOM   3744 O O   . ARG B 1 90  ? 156.583 171.731 144.515 1.00 86.23  ? 90  ARG B O   1 
ATOM   3745 C CB  . ARG B 1 90  ? 153.486 172.563 143.734 1.00 86.23  ? 90  ARG B CB  1 
ATOM   3746 C CG  . ARG B 1 90  ? 153.726 173.879 144.443 1.00 86.23  ? 90  ARG B CG  1 
ATOM   3747 C CD  . ARG B 1 90  ? 152.454 174.404 145.073 1.00 86.23  ? 90  ARG B CD  1 
ATOM   3748 N NE  . ARG B 1 90  ? 151.975 173.531 146.137 1.00 86.23  ? 90  ARG B NE  1 
ATOM   3749 C CZ  . ARG B 1 90  ? 151.453 173.959 147.278 1.00 86.23  ? 90  ARG B CZ  1 
ATOM   3750 N NH1 . ARG B 1 90  ? 151.329 175.250 147.539 1.00 86.23  ? 90  ARG B NH1 1 
ATOM   3751 N NH2 . ARG B 1 90  ? 151.047 173.071 148.180 1.00 86.23  ? 90  ARG B NH2 1 
ATOM   3752 N N   . SER B 1 91  ? 155.214 169.962 144.270 1.00 85.99  ? 91  SER B N   1 
ATOM   3753 C CA  . SER B 1 91  ? 156.049 169.123 145.123 1.00 85.99  ? 91  SER B CA  1 
ATOM   3754 C C   . SER B 1 91  ? 157.379 168.804 144.451 1.00 85.99  ? 91  SER B C   1 
ATOM   3755 O O   . SER B 1 91  ? 158.425 168.765 145.112 1.00 85.99  ? 91  SER B O   1 
ATOM   3756 C CB  . SER B 1 91  ? 155.308 167.836 145.482 1.00 85.99  ? 91  SER B CB  1 
ATOM   3757 O OG  . SER B 1 91  ? 155.199 166.982 144.357 1.00 85.99  ? 91  SER B OG  1 
ATOM   3758 N N   . TRP B 1 92  ? 157.362 168.571 143.137 1.00 83.56  ? 92  TRP B N   1 
ATOM   3759 C CA  . TRP B 1 92  ? 158.587 168.203 142.439 1.00 83.56  ? 92  TRP B CA  1 
ATOM   3760 C C   . TRP B 1 92  ? 159.573 169.360 142.375 1.00 83.56  ? 92  TRP B C   1 
ATOM   3761 O O   . TRP B 1 92  ? 160.783 169.129 142.301 1.00 83.56  ? 92  TRP B O   1 
ATOM   3762 C CB  . TRP B 1 92  ? 158.260 167.696 141.037 1.00 83.56  ? 92  TRP B CB  1 
ATOM   3763 C CG  . TRP B 1 92  ? 158.234 166.207 140.962 1.00 83.56  ? 92  TRP B CG  1 
ATOM   3764 C CD1 . TRP B 1 92  ? 157.132 165.406 140.966 1.00 83.56  ? 92  TRP B CD1 1 
ATOM   3765 C CD2 . TRP B 1 92  ? 159.366 165.333 140.893 1.00 83.56  ? 92  TRP B CD2 1 
ATOM   3766 N NE1 . TRP B 1 92  ? 157.506 164.087 140.895 1.00 83.56  ? 92  TRP B NE1 1 
ATOM   3767 C CE2 . TRP B 1 92  ? 158.873 164.016 140.849 1.00 83.56  ? 92  TRP B CE2 1 
ATOM   3768 C CE3 . TRP B 1 92  ? 160.748 165.538 140.859 1.00 83.56  ? 92  TRP B CE3 1 
ATOM   3769 C CZ2 . TRP B 1 92  ? 159.712 162.907 140.773 1.00 83.56  ? 92  TRP B CZ2 1 
ATOM   3770 C CZ3 . TRP B 1 92  ? 161.580 164.437 140.784 1.00 83.56  ? 92  TRP B CZ3 1 
ATOM   3771 C CH2 . TRP B 1 92  ? 161.060 163.138 140.742 1.00 83.56  ? 92  TRP B CH2 1 
ATOM   3772 N N   . VAL B 1 93  ? 159.082 170.600 142.417 1.00 77.71  ? 93  VAL B N   1 
ATOM   3773 C CA  . VAL B 1 93  ? 159.985 171.749 142.449 1.00 77.71  ? 93  VAL B CA  1 
ATOM   3774 C C   . VAL B 1 93  ? 160.923 171.657 143.647 1.00 77.71  ? 93  VAL B C   1 
ATOM   3775 O O   . VAL B 1 93  ? 162.119 171.956 143.544 1.00 77.71  ? 93  VAL B O   1 
ATOM   3776 C CB  . VAL B 1 93  ? 159.183 173.064 142.453 1.00 77.71  ? 93  VAL B CB  1 
ATOM   3777 C CG1 . VAL B 1 93  ? 160.052 174.220 142.920 1.00 77.71  ? 93  VAL B CG1 1 
ATOM   3778 C CG2 . VAL B 1 93  ? 158.628 173.346 141.068 1.00 77.71  ? 93  VAL B CG2 1 
ATOM   3779 N N   . ILE B 1 94  ? 160.403 171.233 144.799 1.00 74.07  ? 94  ILE B N   1 
ATOM   3780 C CA  . ILE B 1 94  ? 161.250 171.067 145.976 1.00 74.07  ? 94  ILE B CA  1 
ATOM   3781 C C   . ILE B 1 94  ? 161.974 169.724 145.954 1.00 74.07  ? 94  ILE B C   1 
ATOM   3782 O O   . ILE B 1 94  ? 163.117 169.626 146.412 1.00 74.07  ? 94  ILE B O   1 
ATOM   3783 C CB  . ILE B 1 94  ? 160.417 171.228 147.258 1.00 74.07  ? 94  ILE B CB  1 
ATOM   3784 C CG1 . ILE B 1 94  ? 159.626 172.536 147.219 1.00 74.07  ? 94  ILE B CG1 1 
ATOM   3785 C CG2 . ILE B 1 94  ? 161.309 171.180 148.487 1.00 74.07  ? 94  ILE B CG2 1 
ATOM   3786 C CD1 . ILE B 1 94  ? 160.446 173.756 147.567 1.00 74.07  ? 94  ILE B CD1 1 
ATOM   3787 N N   . THR B 1 95  ? 161.335 168.677 145.427 1.00 72.66  ? 95  THR B N   1 
ATOM   3788 C CA  . THR B 1 95  ? 161.941 167.347 145.449 1.00 72.66  ? 95  THR B CA  1 
ATOM   3789 C C   . THR B 1 95  ? 163.166 167.253 144.544 1.00 72.66  ? 95  THR B C   1 
ATOM   3790 O O   . THR B 1 95  ? 164.086 166.473 144.827 1.00 72.66  ? 95  THR B O   1 
ATOM   3791 C CB  . THR B 1 95  ? 160.904 166.300 145.045 1.00 72.66  ? 95  THR B CB  1 
ATOM   3792 O OG1 . THR B 1 95  ? 159.724 166.466 145.841 1.00 72.66  ? 95  THR B OG1 1 
ATOM   3793 C CG2 . THR B 1 95  ? 161.447 164.898 145.248 1.00 72.66  ? 95  THR B CG2 1 
ATOM   3794 N N   . ALA B 1 96  ? 163.193 168.024 143.454 1.00 65.91  ? 96  ALA B N   1 
ATOM   3795 C CA  . ALA B 1 96  ? 164.294 167.923 142.503 1.00 65.91  ? 96  ALA B CA  1 
ATOM   3796 C C   . ALA B 1 96  ? 165.620 168.297 143.149 1.00 65.91  ? 96  ALA B C   1 
ATOM   3797 O O   . ALA B 1 96  ? 166.652 167.678 142.868 1.00 65.91  ? 96  ALA B O   1 
ATOM   3798 C CB  . ALA B 1 96  ? 164.019 168.807 141.288 1.00 65.91  ? 96  ALA B CB  1 
ATOM   3799 N N   . TYR B 1 97  ? 165.614 169.312 144.013 1.00 59.38  ? 97  TYR B N   1 
ATOM   3800 C CA  . TYR B 1 97  ? 166.845 169.713 144.684 1.00 59.38  ? 97  TYR B CA  1 
ATOM   3801 C C   . TYR B 1 97  ? 167.351 168.613 145.608 1.00 59.38  ? 97  TYR B C   1 
ATOM   3802 O O   . TYR B 1 97  ? 168.520 168.217 145.534 1.00 59.38  ? 97  TYR B O   1 
ATOM   3803 C CB  . TYR B 1 97  ? 166.612 171.008 145.462 1.00 59.38  ? 97  TYR B CB  1 
ATOM   3804 C CG  . TYR B 1 97  ? 167.779 171.448 146.316 1.00 59.38  ? 97  TYR B CG  1 
ATOM   3805 C CD1 . TYR B 1 97  ? 168.780 172.251 145.796 1.00 59.38  ? 97  TYR B CD1 1 
ATOM   3806 C CD2 . TYR B 1 97  ? 167.870 171.072 147.648 1.00 59.38  ? 97  TYR B CD2 1 
ATOM   3807 C CE1 . TYR B 1 97  ? 169.841 172.658 146.573 1.00 59.38  ? 97  TYR B CE1 1 
ATOM   3808 C CE2 . TYR B 1 97  ? 168.929 171.473 148.431 1.00 59.38  ? 97  TYR B CE2 1 
ATOM   3809 C CZ  . TYR B 1 97  ? 169.910 172.266 147.890 1.00 59.38  ? 97  TYR B CZ  1 
ATOM   3810 O OH  . TYR B 1 97  ? 170.966 172.669 148.670 1.00 59.38  ? 97  TYR B OH  1 
ATOM   3811 N N   . VAL B 1 98  ? 166.478 168.097 146.478 1.00 61.78  ? 98  VAL B N   1 
ATOM   3812 C CA  . VAL B 1 98  ? 166.921 167.131 147.477 1.00 61.78  ? 98  VAL B CA  1 
ATOM   3813 C C   . VAL B 1 98  ? 167.336 165.822 146.825 1.00 61.78  ? 98  VAL B C   1 
ATOM   3814 O O   . VAL B 1 98  ? 168.210 165.121 147.348 1.00 61.78  ? 98  VAL B O   1 
ATOM   3815 C CB  . VAL B 1 98  ? 165.839 166.904 148.550 1.00 61.78  ? 98  VAL B CB  1 
ATOM   3816 C CG1 . VAL B 1 98  ? 165.532 168.201 149.273 1.00 61.78  ? 98  VAL B CG1 1 
ATOM   3817 C CG2 . VAL B 1 98  ? 164.585 166.318 147.941 1.00 61.78  ? 98  VAL B CG2 1 
ATOM   3818 N N   . LEU B 1 99  ? 166.746 165.471 145.677 1.00 63.21  ? 99  LEU B N   1 
ATOM   3819 C CA  . LEU B 1 99  ? 167.123 164.225 145.017 1.00 63.21  ? 99  LEU B CA  1 
ATOM   3820 C C   . LEU B 1 99  ? 168.615 164.195 144.704 1.00 63.21  ? 99  LEU B C   1 
ATOM   3821 O O   . LEU B 1 99  ? 169.330 163.275 145.117 1.00 63.21  ? 99  LEU B O   1 
ATOM   3822 C CB  . LEU B 1 99  ? 166.303 164.042 143.741 1.00 63.21  ? 99  LEU B CB  1 
ATOM   3823 C CG  . LEU B 1 99  ? 166.375 162.668 143.079 1.00 63.21  ? 99  LEU B CG  1 
ATOM   3824 C CD1 . LEU B 1 99  ? 165.584 161.654 143.881 1.00 63.21  ? 99  LEU B CD1 1 
ATOM   3825 C CD2 . LEU B 1 99  ? 165.870 162.733 141.651 1.00 63.21  ? 99  LEU B CD2 1 
ATOM   3826 N N   . THR B 1 100 ? 169.112 165.220 144.010 1.00 58.36  ? 100 THR B N   1 
ATOM   3827 C CA  . THR B 1 100 ? 170.531 165.281 143.684 1.00 58.36  ? 100 THR B CA  1 
ATOM   3828 C C   . THR B 1 100 ? 171.386 165.763 144.848 1.00 58.36  ? 100 THR B C   1 
ATOM   3829 O O   . THR B 1 100 ? 172.602 165.553 144.828 1.00 58.36  ? 100 THR B O   1 
ATOM   3830 C CB  . THR B 1 100 ? 170.765 166.190 142.478 1.00 58.36  ? 100 THR B CB  1 
ATOM   3831 O OG1 . THR B 1 100 ? 169.996 167.387 142.626 1.00 58.36  ? 100 THR B OG1 1 
ATOM   3832 C CG2 . THR B 1 100 ? 170.361 165.490 141.197 1.00 58.36  ? 100 THR B CG2 1 
ATOM   3833 N N   . PHE B 1 101 ? 170.790 166.404 145.855 1.00 58.39  ? 101 PHE B N   1 
ATOM   3834 C CA  . PHE B 1 101 ? 171.569 166.799 147.023 1.00 58.39  ? 101 PHE B CA  1 
ATOM   3835 C C   . PHE B 1 101 ? 171.928 165.593 147.878 1.00 58.39  ? 101 PHE B C   1 
ATOM   3836 O O   . PHE B 1 101 ? 173.064 165.477 148.350 1.00 58.39  ? 101 PHE B O   1 
ATOM   3837 C CB  . PHE B 1 101 ? 170.797 167.834 147.838 1.00 58.39  ? 101 PHE B CB  1 
ATOM   3838 C CG  . PHE B 1 101 ? 171.489 168.254 149.099 1.00 58.39  ? 101 PHE B CG  1 
ATOM   3839 C CD1 . PHE B 1 101 ? 172.793 168.709 149.071 1.00 58.39  ? 101 PHE B CD1 1 
ATOM   3840 C CD2 . PHE B 1 101 ? 170.830 168.203 150.314 1.00 58.39  ? 101 PHE B CD2 1 
ATOM   3841 C CE1 . PHE B 1 101 ? 173.430 169.100 150.230 1.00 58.39  ? 101 PHE B CE1 1 
ATOM   3842 C CE2 . PHE B 1 101 ? 171.462 168.592 151.475 1.00 58.39  ? 101 PHE B CE2 1 
ATOM   3843 C CZ  . PHE B 1 101 ? 172.764 169.042 151.432 1.00 58.39  ? 101 PHE B CZ  1 
ATOM   3844 N N   . GLY B 1 102 ? 170.978 164.685 148.089 1.00 61.26  ? 102 GLY B N   1 
ATOM   3845 C CA  . GLY B 1 102 ? 171.237 163.487 148.858 1.00 61.26  ? 102 GLY B CA  1 
ATOM   3846 C C   . GLY B 1 102 ? 171.823 162.357 148.039 1.00 61.26  ? 102 GLY B C   1 
ATOM   3847 O O   . GLY B 1 102 ? 172.459 161.456 148.589 1.00 61.26  ? 102 GLY B O   1 
ATOM   3848 N N   . GLY B 1 103 ? 171.612 162.385 146.722 1.00 61.99  ? 103 GLY B N   1 
ATOM   3849 C CA  . GLY B 1 103 ? 172.157 161.335 145.880 1.00 61.99  ? 103 GLY B CA  1 
ATOM   3850 C C   . GLY B 1 103 ? 173.669 161.372 145.773 1.00 61.99  ? 103 GLY B C   1 
ATOM   3851 O O   . GLY B 1 103 ? 174.326 160.329 145.803 1.00 61.99  ? 103 GLY B O   1 
ATOM   3852 N N   . LEU B 1 104 ? 174.243 162.566 145.657 1.00 60.04  ? 104 LEU B N   1 
ATOM   3853 C CA  . LEU B 1 104 ? 175.649 162.741 145.306 1.00 60.04  ? 104 LEU B CA  1 
ATOM   3854 C C   . LEU B 1 104 ? 176.459 163.374 146.433 1.00 60.04  ? 104 LEU B C   1 
ATOM   3855 O O   . LEU B 1 104 ? 177.290 164.248 146.193 1.00 60.04  ? 104 LEU B O   1 
ATOM   3856 C CB  . LEU B 1 104 ? 175.783 163.588 144.045 1.00 60.04  ? 104 LEU B CB  1 
ATOM   3857 C CG  . LEU B 1 104 ? 175.257 163.026 142.727 1.00 60.04  ? 104 LEU B CG  1 
ATOM   3858 C CD1 . LEU B 1 104 ? 175.037 164.151 141.737 1.00 60.04  ? 104 LEU B CD1 1 
ATOM   3859 C CD2 . LEU B 1 104 ? 176.227 162.010 142.163 1.00 60.04  ? 104 LEU B CD2 1 
ATOM   3860 N N   . MET B 1 105 ? 176.241 162.945 147.674 1.00 59.50  ? 105 MET B N   1 
ATOM   3861 C CA  . MET B 1 105 ? 176.977 163.560 148.771 1.00 59.50  ? 105 MET B CA  1 
ATOM   3862 C C   . MET B 1 105 ? 178.207 162.756 149.181 1.00 59.50  ? 105 MET B C   1 
ATOM   3863 O O   . MET B 1 105 ? 179.249 163.342 149.490 1.00 59.50  ? 105 MET B O   1 
ATOM   3864 C CB  . MET B 1 105 ? 176.058 163.770 149.974 1.00 59.50  ? 105 MET B CB  1 
ATOM   3865 C CG  . MET B 1 105 ? 176.723 164.518 151.111 1.00 59.50  ? 105 MET B CG  1 
ATOM   3866 S SD  . MET B 1 105 ? 175.641 164.780 152.520 1.00 59.50  ? 105 MET B SD  1 
ATOM   3867 C CE  . MET B 1 105 ? 174.532 166.017 151.863 1.00 59.50  ? 105 MET B CE  1 
ATOM   3868 N N   . LEU B 1 106 ? 178.116 161.424 149.196 1.00 61.61  ? 106 LEU B N   1 
ATOM   3869 C CA  . LEU B 1 106 ? 179.296 160.611 149.481 1.00 61.61  ? 106 LEU B CA  1 
ATOM   3870 C C   . LEU B 1 106 ? 180.343 160.755 148.382 1.00 61.61  ? 106 LEU B C   1 
ATOM   3871 O O   . LEU B 1 106 ? 181.548 160.848 148.663 1.00 61.61  ? 106 LEU B O   1 
ATOM   3872 C CB  . LEU B 1 106 ? 178.890 159.149 149.653 1.00 61.61  ? 106 LEU B CB  1 
ATOM   3873 C CG  . LEU B 1 106 ? 177.943 158.849 150.814 1.00 61.61  ? 106 LEU B CG  1 
ATOM   3874 C CD1 . LEU B 1 106 ? 177.519 157.393 150.788 1.00 61.61  ? 106 LEU B CD1 1 
ATOM   3875 C CD2 . LEU B 1 106 ? 178.596 159.194 152.138 1.00 61.61  ? 106 LEU B CD2 1 
ATOM   3876 N N   . LEU B 1 107 ? 179.901 160.776 147.123 1.00 61.06  ? 107 LEU B N   1 
ATOM   3877 C CA  . LEU B 1 107 ? 180.819 161.034 146.021 1.00 61.06  ? 107 LEU B CA  1 
ATOM   3878 C C   . LEU B 1 107 ? 181.451 162.412 146.151 1.00 61.06  ? 107 LEU B C   1 
ATOM   3879 O O   . LEU B 1 107 ? 182.645 162.582 145.883 1.00 61.06  ? 107 LEU B O   1 
ATOM   3880 C CB  . LEU B 1 107 ? 180.089 160.902 144.686 1.00 61.06  ? 107 LEU B CB  1 
ATOM   3881 C CG  . LEU B 1 107 ? 180.877 161.324 143.444 1.00 61.06  ? 107 LEU B CG  1 
ATOM   3882 C CD1 . LEU B 1 107 ? 182.115 160.464 143.276 1.00 61.06  ? 107 LEU B CD1 1 
ATOM   3883 C CD2 . LEU B 1 107 ? 180.003 161.257 142.206 1.00 61.06  ? 107 LEU B CD2 1 
ATOM   3884 N N   . GLY B 1 108 ? 180.664 163.410 146.555 1.00 57.68  ? 108 GLY B N   1 
ATOM   3885 C CA  . GLY B 1 108 ? 181.223 164.733 146.771 1.00 57.68  ? 108 GLY B CA  1 
ATOM   3886 C C   . GLY B 1 108 ? 182.248 164.755 147.887 1.00 57.68  ? 108 GLY B C   1 
ATOM   3887 O O   . GLY B 1 108 ? 183.231 165.497 147.827 1.00 57.68  ? 108 GLY B O   1 
ATOM   3888 N N   . GLY B 1 109 ? 182.028 163.949 148.925 1.00 58.42  ? 109 GLY B N   1 
ATOM   3889 C CA  . GLY B 1 109 ? 183.006 163.858 149.996 1.00 58.42  ? 109 GLY B CA  1 
ATOM   3890 C C   . GLY B 1 109 ? 184.309 163.227 149.547 1.00 58.42  ? 109 GLY B C   1 
ATOM   3891 O O   . GLY B 1 109 ? 185.392 163.682 149.924 1.00 58.42  ? 109 GLY B O   1 
ATOM   3892 N N   . ARG B 1 110 ? 184.227 162.173 148.738 1.00 63.19  ? 110 ARG B N   1 
ATOM   3893 C CA  . ARG B 1 110 ? 185.435 161.488 148.285 1.00 63.19  ? 110 ARG B CA  1 
ATOM   3894 C C   . ARG B 1 110 ? 186.130 162.190 147.115 1.00 63.19  ? 110 ARG B C   1 
ATOM   3895 O O   . ARG B 1 110 ? 187.318 161.943 146.881 1.00 63.19  ? 110 ARG B O   1 
ATOM   3896 C CB  . ARG B 1 110 ? 185.086 160.036 147.929 1.00 63.19  ? 110 ARG B CB  1 
ATOM   3897 C CG  . ARG B 1 110 ? 186.205 159.215 147.306 1.00 63.19  ? 110 ARG B CG  1 
ATOM   3898 C CD  . ARG B 1 110 ? 187.441 159.116 148.195 1.00 63.19  ? 110 ARG B CD  1 
ATOM   3899 N NE  . ARG B 1 110 ? 187.257 158.291 149.382 1.00 63.19  ? 110 ARG B NE  1 
ATOM   3900 C CZ  . ARG B 1 110 ? 188.136 158.211 150.371 1.00 63.19  ? 110 ARG B CZ  1 
ATOM   3901 N NH1 . ARG B 1 110 ? 189.243 158.933 150.371 1.00 63.19  ? 110 ARG B NH1 1 
ATOM   3902 N NH2 . ARG B 1 110 ? 187.906 157.376 151.379 1.00 63.19  ? 110 ARG B NH2 1 
ATOM   3903 N N   . LEU B 1 111 ? 185.445 163.091 146.407 1.00 60.87  ? 111 LEU B N   1 
ATOM   3904 C CA  . LEU B 1 111 ? 186.018 163.691 145.202 1.00 60.87  ? 111 LEU B CA  1 
ATOM   3905 C C   . LEU B 1 111 ? 187.156 164.662 145.508 1.00 60.87  ? 111 LEU B C   1 
ATOM   3906 O O   . LEU B 1 111 ? 188.025 164.888 144.653 1.00 60.87  ? 111 LEU B O   1 
ATOM   3907 C CB  . LEU B 1 111 ? 184.912 164.399 144.420 1.00 60.87  ? 111 LEU B CB  1 
ATOM   3908 C CG  . LEU B 1 111 ? 185.210 164.895 143.009 1.00 60.87  ? 111 LEU B CG  1 
ATOM   3909 C CD1 . LEU B 1 111 ? 185.532 163.726 142.099 1.00 60.87  ? 111 LEU B CD1 1 
ATOM   3910 C CD2 . LEU B 1 111 ? 184.026 165.680 142.480 1.00 60.87  ? 111 LEU B CD2 1 
ATOM   3911 N N   . GLY B 1 112 ? 187.164 165.252 146.704 1.00 61.52  ? 112 GLY B N   1 
ATOM   3912 C CA  . GLY B 1 112 ? 188.185 166.235 147.029 1.00 61.52  ? 112 GLY B CA  1 
ATOM   3913 C C   . GLY B 1 112 ? 189.580 165.644 147.087 1.00 61.52  ? 112 GLY B C   1 
ATOM   3914 O O   . GLY B 1 112 ? 190.557 166.301 146.721 1.00 61.52  ? 112 GLY B O   1 
ATOM   3915 N N   . ASP B 1 113 ? 189.697 164.402 147.557 1.00 67.99  ? 113 ASP B N   1 
ATOM   3916 C CA  . ASP B 1 113 ? 190.993 163.736 147.590 1.00 67.99  ? 113 ASP B CA  1 
ATOM   3917 C C   . ASP B 1 113 ? 191.531 163.452 146.194 1.00 67.99  ? 113 ASP B C   1 
ATOM   3918 O O   . ASP B 1 113 ? 192.746 163.305 146.031 1.00 67.99  ? 113 ASP B O   1 
ATOM   3919 C CB  . ASP B 1 113 ? 190.891 162.432 148.379 1.00 67.99  ? 113 ASP B CB  1 
ATOM   3920 C CG  . ASP B 1 113 ? 190.660 162.662 149.856 1.00 67.99  ? 113 ASP B CG  1 
ATOM   3921 O OD1 . ASP B 1 113 ? 191.106 163.707 150.371 1.00 67.99  ? 113 ASP B OD1 1 
ATOM   3922 O OD2 . ASP B 1 113 ? 190.033 161.800 150.504 1.00 67.99  ? 113 ASP B OD2 1 
ATOM   3923 N N   . THR B 1 114 ? 190.659 163.371 145.191 1.00 69.01  ? 114 THR B N   1 
ATOM   3924 C CA  . THR B 1 114 ? 191.070 163.085 143.823 1.00 69.01  ? 114 THR B CA  1 
ATOM   3925 C C   . THR B 1 114 ? 191.363 164.349 143.026 1.00 69.01  ? 114 THR B C   1 
ATOM   3926 O O   . THR B 1 114 ? 192.311 164.373 142.234 1.00 69.01  ? 114 THR B O   1 
ATOM   3927 C CB  . THR B 1 114 ? 189.991 162.269 143.111 1.00 69.01  ? 114 THR B CB  1 
ATOM   3928 O OG1 . THR B 1 114 ? 189.617 161.156 143.931 1.00 69.01  ? 114 THR B OG1 1 
ATOM   3929 C CG2 . THR B 1 114 ? 190.502 161.756 141.779 1.00 69.01  ? 114 THR B CG2 1 
ATOM   3930 N N   . ILE B 1 115 ? 190.572 165.402 143.211 1.00 65.39  ? 115 ILE B N   1 
ATOM   3931 C CA  . ILE B 1 115 ? 190.743 166.633 142.450 1.00 65.39  ? 115 ILE B CA  1 
ATOM   3932 C C   . ILE B 1 115 ? 191.484 167.697 143.252 1.00 65.39  ? 115 ILE B C   1 
ATOM   3933 O O   . ILE B 1 115 ? 192.391 168.346 142.734 1.00 65.39  ? 115 ILE B O   1 
ATOM   3934 C CB  . ILE B 1 115 ? 189.375 167.157 141.965 1.00 65.39  ? 115 ILE B CB  1 
ATOM   3935 C CG1 . ILE B 1 115 ? 188.674 166.101 141.113 1.00 65.39  ? 115 ILE B CG1 1 
ATOM   3936 C CG2 . ILE B 1 115 ? 189.541 168.443 141.181 1.00 65.39  ? 115 ILE B CG2 1 
ATOM   3937 C CD1 . ILE B 1 115 ? 189.317 165.883 139.764 1.00 65.39  ? 115 ILE B CD1 1 
ATOM   3938 N N   . GLY B 1 116 ? 191.115 167.882 144.514 1.00 62.69  ? 116 GLY B N   1 
ATOM   3939 C CA  . GLY B 1 116 ? 191.637 168.969 145.318 1.00 62.69  ? 116 GLY B CA  1 
ATOM   3940 C C   . GLY B 1 116 ? 190.505 169.707 145.997 1.00 62.69  ? 116 GLY B C   1 
ATOM   3941 O O   . GLY B 1 116 ? 189.545 170.111 145.335 1.00 62.69  ? 116 GLY B O   1 
ATOM   3942 N N   . ARG B 1 117 ? 190.594 169.882 147.316 1.00 57.90  ? 117 ARG B N   1 
ATOM   3943 C CA  . ARG B 1 117 ? 189.454 170.403 148.064 1.00 57.90  ? 117 ARG B CA  1 
ATOM   3944 C C   . ARG B 1 117 ? 189.127 171.838 147.671 1.00 57.90  ? 117 ARG B C   1 
ATOM   3945 O O   . ARG B 1 117 ? 187.951 172.198 147.550 1.00 57.90  ? 117 ARG B O   1 
ATOM   3946 C CB  . ARG B 1 117 ? 189.717 170.293 149.564 1.00 57.90  ? 117 ARG B CB  1 
ATOM   3947 C CG  . ARG B 1 117 ? 189.491 168.893 150.096 1.00 57.90  ? 117 ARG B CG  1 
ATOM   3948 C CD  . ARG B 1 117 ? 189.732 168.798 151.583 1.00 57.90  ? 117 ARG B CD  1 
ATOM   3949 N NE  . ARG B 1 117 ? 189.679 167.414 152.032 1.00 57.90  ? 117 ARG B NE  1 
ATOM   3950 C CZ  . ARG B 1 117 ? 190.704 166.575 151.985 1.00 57.90  ? 117 ARG B CZ  1 
ATOM   3951 N NH1 . ARG B 1 117 ? 191.887 166.956 151.534 1.00 57.90  ? 117 ARG B NH1 1 
ATOM   3952 N NH2 . ARG B 1 117 ? 190.538 165.324 152.399 1.00 57.90  ? 117 ARG B NH2 1 
ATOM   3953 N N   . LYS B 1 118 ? 190.147 172.672 147.469 1.00 61.51  ? 118 LYS B N   1 
ATOM   3954 C CA  . LYS B 1 118 ? 189.900 174.052 147.065 1.00 61.51  ? 118 LYS B CA  1 
ATOM   3955 C C   . LYS B 1 118 ? 189.214 174.111 145.705 1.00 61.51  ? 118 LYS B C   1 
ATOM   3956 O O   . LYS B 1 118 ? 188.220 174.829 145.523 1.00 61.51  ? 118 LYS B O   1 
ATOM   3957 C CB  . LYS B 1 118 ? 191.219 174.823 147.042 1.00 61.51  ? 118 LYS B CB  1 
ATOM   3958 C CG  . LYS B 1 118 ? 191.099 176.270 146.616 1.00 61.51  ? 118 LYS B CG  1 
ATOM   3959 C CD  . LYS B 1 118 ? 192.461 176.936 146.592 1.00 61.51  ? 118 LYS B CD  1 
ATOM   3960 C CE  . LYS B 1 118 ? 192.385 178.326 145.997 1.00 61.51  ? 118 LYS B CE  1 
ATOM   3961 N NZ  . LYS B 1 118 ? 193.726 178.964 145.923 1.00 61.51  ? 118 LYS B NZ  1 
ATOM   3962 N N   . ARG B 1 119 ? 189.724 173.344 144.739 1.00 61.98  ? 119 ARG B N   1 
ATOM   3963 C CA  . ARG B 1 119 ? 189.134 173.335 143.406 1.00 61.98  ? 119 ARG B CA  1 
ATOM   3964 C C   . ARG B 1 119 ? 187.716 172.783 143.430 1.00 61.98  ? 119 ARG B C   1 
ATOM   3965 O O   . ARG B 1 119 ? 186.828 173.311 142.753 1.00 61.98  ? 119 ARG B O   1 
ATOM   3966 C CB  . ARG B 1 119 ? 190.005 172.524 142.451 1.00 61.98  ? 119 ARG B CB  1 
ATOM   3967 C CG  . ARG B 1 119 ? 189.548 172.581 141.008 1.00 61.98  ? 119 ARG B CG  1 
ATOM   3968 C CD  . ARG B 1 119 ? 190.723 172.710 140.060 1.00 61.98  ? 119 ARG B CD  1 
ATOM   3969 N NE  . ARG B 1 119 ? 191.589 171.539 140.105 1.00 61.98  ? 119 ARG B NE  1 
ATOM   3970 C CZ  . ARG B 1 119 ? 192.913 171.584 140.044 1.00 61.98  ? 119 ARG B CZ  1 
ATOM   3971 N NH1 . ARG B 1 119 ? 193.561 172.732 139.936 1.00 61.98  ? 119 ARG B NH1 1 
ATOM   3972 N NH2 . ARG B 1 119 ? 193.603 170.448 140.092 1.00 61.98  ? 119 ARG B NH2 1 
ATOM   3973 N N   . THR B 1 120 ? 187.485 171.716 144.198 1.00 55.46  ? 120 THR B N   1 
ATOM   3974 C CA  . THR B 1 120 ? 186.145 171.146 144.290 1.00 55.46  ? 120 THR B CA  1 
ATOM   3975 C C   . THR B 1 120 ? 185.166 172.133 144.913 1.00 55.46  ? 120 THR B C   1 
ATOM   3976 O O   . THR B 1 120 ? 184.029 172.274 144.446 1.00 55.46  ? 120 THR B O   1 
ATOM   3977 C CB  . THR B 1 120 ? 186.185 169.848 145.092 1.00 55.46  ? 120 THR B CB  1 
ATOM   3978 O OG1 . THR B 1 120 ? 187.241 169.018 144.599 1.00 55.46  ? 120 THR B OG1 1 
ATOM   3979 C CG2 . THR B 1 120 ? 184.873 169.104 144.964 1.00 55.46  ? 120 THR B CG2 1 
ATOM   3980 N N   . PHE B 1 121 ? 185.592 172.829 145.968 1.00 53.89  ? 121 PHE B N   1 
ATOM   3981 C CA  . PHE B 1 121 ? 184.748 173.841 146.593 1.00 53.89  ? 121 PHE B CA  1 
ATOM   3982 C C   . PHE B 1 121 ? 184.387 174.939 145.600 1.00 53.89  ? 121 PHE B C   1 
ATOM   3983 O O   . PHE B 1 121 ? 183.215 175.325 145.475 1.00 53.89  ? 121 PHE B O   1 
ATOM   3984 C CB  . PHE B 1 121 ? 185.474 174.420 147.809 1.00 53.89  ? 121 PHE B CB  1 
ATOM   3985 C CG  . PHE B 1 121 ? 184.592 175.196 148.739 1.00 53.89  ? 121 PHE B CG  1 
ATOM   3986 C CD1 . PHE B 1 121 ? 183.616 174.562 149.482 1.00 53.89  ? 121 PHE B CD1 1 
ATOM   3987 C CD2 . PHE B 1 121 ? 184.754 176.561 148.886 1.00 53.89  ? 121 PHE B CD2 1 
ATOM   3988 C CE1 . PHE B 1 121 ? 182.810 175.275 150.342 1.00 53.89  ? 121 PHE B CE1 1 
ATOM   3989 C CE2 . PHE B 1 121 ? 183.952 177.279 149.742 1.00 53.89  ? 121 PHE B CE2 1 
ATOM   3990 C CZ  . PHE B 1 121 ? 182.979 176.635 150.471 1.00 53.89  ? 121 PHE B CZ  1 
ATOM   3991 N N   . ILE B 1 122 ? 185.385 175.442 144.869 1.00 55.42  ? 122 ILE B N   1 
ATOM   3992 C CA  . ILE B 1 122 ? 185.139 176.520 143.915 1.00 55.42  ? 122 ILE B CA  1 
ATOM   3993 C C   . ILE B 1 122 ? 184.198 176.057 142.808 1.00 55.42  ? 122 ILE B C   1 
ATOM   3994 O O   . ILE B 1 122 ? 183.276 176.783 142.411 1.00 55.42  ? 122 ILE B O   1 
ATOM   3995 C CB  . ILE B 1 122 ? 186.471 177.044 143.350 1.00 55.42  ? 122 ILE B CB  1 
ATOM   3996 C CG1 . ILE B 1 122 ? 187.254 177.775 144.440 1.00 55.42  ? 122 ILE B CG1 1 
ATOM   3997 C CG2 . ILE B 1 122 ? 186.227 177.966 142.172 1.00 55.42  ? 122 ILE B CG2 1 
ATOM   3998 C CD1 . ILE B 1 122 ? 188.718 177.945 144.126 1.00 55.42  ? 122 ILE B CD1 1 
ATOM   3999 N N   . VAL B 1 123 ? 184.412 174.843 142.296 1.00 54.04  ? 123 VAL B N   1 
ATOM   4000 C CA  . VAL B 1 123 ? 183.571 174.319 141.224 1.00 54.04  ? 123 VAL B CA  1 
ATOM   4001 C C   . VAL B 1 123 ? 182.133 174.164 141.697 1.00 54.04  ? 123 VAL B C   1 
ATOM   4002 O O   . VAL B 1 123 ? 181.187 174.518 140.982 1.00 54.04  ? 123 VAL B O   1 
ATOM   4003 C CB  . VAL B 1 123 ? 184.143 172.990 140.701 1.00 54.04  ? 123 VAL B CB  1 
ATOM   4004 C CG1 . VAL B 1 123 ? 183.092 172.226 139.920 1.00 54.04  ? 123 VAL B CG1 1 
ATOM   4005 C CG2 . VAL B 1 123 ? 185.367 173.245 139.841 1.00 54.04  ? 123 VAL B CG2 1 
ATOM   4006 N N   . GLY B 1 124 ? 181.941 173.634 142.908 1.00 52.90  ? 124 GLY B N   1 
ATOM   4007 C CA  . GLY B 1 124 ? 180.592 173.489 143.430 1.00 52.90  ? 124 GLY B CA  1 
ATOM   4008 C C   . GLY B 1 124 ? 179.881 174.818 143.600 1.00 52.90  ? 124 GLY B C   1 
ATOM   4009 O O   . GLY B 1 124 ? 178.711 174.958 143.231 1.00 52.90  ? 124 GLY B O   1 
ATOM   4010 N N   . VAL B 1 125 ? 180.579 175.815 144.151 1.00 53.32  ? 125 VAL B N   1 
ATOM   4011 C CA  . VAL B 1 125 ? 179.959 177.126 144.338 1.00 53.32  ? 125 VAL B CA  1 
ATOM   4012 C C   . VAL B 1 125 ? 179.596 177.747 142.992 1.00 53.32  ? 125 VAL B C   1 
ATOM   4013 O O   . VAL B 1 125 ? 178.511 178.325 142.828 1.00 53.32  ? 125 VAL B O   1 
ATOM   4014 C CB  . VAL B 1 125 ? 180.881 178.044 145.162 1.00 53.32  ? 125 VAL B CB  1 
ATOM   4015 C CG1 . VAL B 1 125 ? 180.269 179.421 145.295 1.00 53.32  ? 125 VAL B CG1 1 
ATOM   4016 C CG2 . VAL B 1 125 ? 181.124 177.452 146.534 1.00 53.32  ? 125 VAL B CG2 1 
ATOM   4017 N N   . ALA B 1 126 ? 180.494 177.640 142.007 1.00 53.29  ? 126 ALA B N   1 
ATOM   4018 C CA  . ALA B 1 126 ? 180.216 178.201 140.688 1.00 53.29  ? 126 ALA B CA  1 
ATOM   4019 C C   . ALA B 1 126 ? 179.018 177.521 140.033 1.00 53.29  ? 126 ALA B C   1 
ATOM   4020 O O   . ALA B 1 126 ? 178.166 178.190 139.429 1.00 53.29  ? 126 ALA B O   1 
ATOM   4021 C CB  . ALA B 1 126 ? 181.451 178.081 139.798 1.00 53.29  ? 126 ALA B CB  1 
ATOM   4022 N N   . LEU B 1 127 ? 178.939 176.192 140.134 1.00 52.67  ? 127 LEU B N   1 
ATOM   4023 C CA  . LEU B 1 127 ? 177.800 175.479 139.567 1.00 52.67  ? 127 LEU B CA  1 
ATOM   4024 C C   . LEU B 1 127 ? 176.503 175.894 140.245 1.00 52.67  ? 127 LEU B C   1 
ATOM   4025 O O   . LEU B 1 127 ? 175.479 176.083 139.577 1.00 52.67  ? 127 LEU B O   1 
ATOM   4026 C CB  . LEU B 1 127 ? 178.010 173.972 139.687 1.00 52.67  ? 127 LEU B CB  1 
ATOM   4027 C CG  . LEU B 1 127 ? 176.985 173.087 138.978 1.00 52.67  ? 127 LEU B CG  1 
ATOM   4028 C CD1 . LEU B 1 127 ? 176.971 173.379 137.493 1.00 52.67  ? 127 LEU B CD1 1 
ATOM   4029 C CD2 . LEU B 1 127 ? 177.285 171.624 139.230 1.00 52.67  ? 127 LEU B CD2 1 
ATOM   4030 N N   . PHE B 1 128 ? 176.528 176.053 141.571 1.00 53.72  ? 128 PHE B N   1 
ATOM   4031 C CA  . PHE B 1 128 ? 175.336 176.500 142.284 1.00 53.72  ? 128 PHE B CA  1 
ATOM   4032 C C   . PHE B 1 128 ? 174.891 177.878 141.809 1.00 53.72  ? 128 PHE B C   1 
ATOM   4033 O O   . PHE B 1 128 ? 173.696 178.113 141.596 1.00 53.72  ? 128 PHE B O   1 
ATOM   4034 C CB  . PHE B 1 128 ? 175.605 176.509 143.789 1.00 53.72  ? 128 PHE B CB  1 
ATOM   4035 C CG  . PHE B 1 128 ? 174.383 176.749 144.630 1.00 53.72  ? 128 PHE B CG  1 
ATOM   4036 C CD1 . PHE B 1 128 ? 173.991 178.034 144.959 1.00 53.72  ? 128 PHE B CD1 1 
ATOM   4037 C CD2 . PHE B 1 128 ? 173.639 175.689 145.110 1.00 53.72  ? 128 PHE B CD2 1 
ATOM   4038 C CE1 . PHE B 1 128 ? 172.875 178.254 145.734 1.00 53.72  ? 128 PHE B CE1 1 
ATOM   4039 C CE2 . PHE B 1 128 ? 172.522 175.906 145.889 1.00 53.72  ? 128 PHE B CE2 1 
ATOM   4040 C CZ  . PHE B 1 128 ? 172.141 177.189 146.200 1.00 53.72  ? 128 PHE B CZ  1 
ATOM   4041 N N   . THR B 1 129 ? 175.840 178.800 141.626 1.00 55.65  ? 129 THR B N   1 
ATOM   4042 C CA  . THR B 1 129 ? 175.488 180.152 141.195 1.00 55.65  ? 129 THR B CA  1 
ATOM   4043 C C   . THR B 1 129 ? 174.887 180.152 139.790 1.00 55.65  ? 129 THR B C   1 
ATOM   4044 O O   . THR B 1 129 ? 173.854 180.792 139.538 1.00 55.65  ? 129 THR B O   1 
ATOM   4045 C CB  . THR B 1 129 ? 176.721 181.051 141.253 1.00 55.65  ? 129 THR B CB  1 
ATOM   4046 O OG1 . THR B 1 129 ? 177.147 181.188 142.614 1.00 55.65  ? 129 THR B OG1 1 
ATOM   4047 C CG2 . THR B 1 129 ? 176.410 182.423 140.689 1.00 55.65  ? 129 THR B CG2 1 
ATOM   4048 N N   . ILE B 1 130 ? 175.519 179.432 138.861 1.00 55.62  ? 130 ILE B N   1 
ATOM   4049 C CA  . ILE B 1 130 ? 175.010 179.396 137.491 1.00 55.62  ? 130 ILE B CA  1 
ATOM   4050 C C   . ILE B 1 130 ? 173.631 178.748 137.452 1.00 55.62  ? 130 ILE B C   1 
ATOM   4051 O O   . ILE B 1 130 ? 172.732 179.193 136.725 1.00 55.62  ? 130 ILE B O   1 
ATOM   4052 C CB  . ILE B 1 130 ? 176.006 178.671 136.570 1.00 55.62  ? 130 ILE B CB  1 
ATOM   4053 C CG1 . ILE B 1 130 ? 177.338 179.417 136.541 1.00 55.62  ? 130 ILE B CG1 1 
ATOM   4054 C CG2 . ILE B 1 130 ? 175.451 178.557 135.166 1.00 55.62  ? 130 ILE B CG2 1 
ATOM   4055 C CD1 . ILE B 1 130 ? 178.457 178.628 135.912 1.00 55.62  ? 130 ILE B CD1 1 
ATOM   4056 N N   . SER B 1 131 ? 173.437 177.690 138.240 1.00 57.03  ? 131 SER B N   1 
ATOM   4057 C CA  . SER B 1 131 ? 172.142 177.029 138.276 1.00 57.03  ? 131 SER B CA  1 
ATOM   4058 C C   . SER B 1 131 ? 171.073 177.920 138.894 1.00 57.03  ? 131 SER B C   1 
ATOM   4059 O O   . SER B 1 131 ? 169.909 177.856 138.491 1.00 57.03  ? 131 SER B O   1 
ATOM   4060 C CB  . SER B 1 131 ? 172.268 175.720 139.041 1.00 57.03  ? 131 SER B CB  1 
ATOM   4061 O OG  . SER B 1 131 ? 173.140 174.845 138.357 1.00 57.03  ? 131 SER B OG  1 
ATOM   4062 N N   . SER B 1 132 ? 171.442 178.754 139.869 1.00 58.52  ? 132 SER B N   1 
ATOM   4063 C CA  . SER B 1 132 ? 170.494 179.727 140.402 1.00 58.52  ? 132 SER B CA  1 
ATOM   4064 C C   . SER B 1 132 ? 170.090 180.739 139.338 1.00 58.52  ? 132 SER B C   1 
ATOM   4065 O O   . SER B 1 132 ? 168.919 181.134 139.252 1.00 58.52  ? 132 SER B O   1 
ATOM   4066 C CB  . SER B 1 132 ? 171.095 180.433 141.615 1.00 58.52  ? 132 SER B CB  1 
ATOM   4067 O OG  . SER B 1 132 ? 170.189 181.376 142.154 1.00 58.52  ? 132 SER B OG  1 
ATOM   4068 N N   . VAL B 1 133 ? 171.051 181.176 138.520 1.00 60.05  ? 133 VAL B N   1 
ATOM   4069 C CA  . VAL B 1 133 ? 170.715 182.060 137.403 1.00 60.05  ? 133 VAL B CA  1 
ATOM   4070 C C   . VAL B 1 133 ? 169.720 181.380 136.469 1.00 60.05  ? 133 VAL B C   1 
ATOM   4071 O O   . VAL B 1 133 ? 168.724 181.984 136.045 1.00 60.05  ? 133 VAL B O   1 
ATOM   4072 C CB  . VAL B 1 133 ? 171.987 182.485 136.648 1.00 60.05  ? 133 VAL B CB  1 
ATOM   4073 C CG1 . VAL B 1 133 ? 171.621 183.308 135.430 1.00 60.05  ? 133 VAL B CG1 1 
ATOM   4074 C CG2 . VAL B 1 133 ? 172.911 183.261 137.559 1.00 60.05  ? 133 VAL B CG2 1 
ATOM   4075 N N   . LEU B 1 134 ? 169.970 180.111 136.142 1.00 61.80  ? 134 LEU B N   1 
ATOM   4076 C CA  . LEU B 1 134 ? 169.055 179.380 135.267 1.00 61.80  ? 134 LEU B CA  1 
ATOM   4077 C C   . LEU B 1 134 ? 167.674 179.235 135.899 1.00 61.80  ? 134 LEU B C   1 
ATOM   4078 O O   . LEU B 1 134 ? 166.656 179.282 135.199 1.00 61.80  ? 134 LEU B O   1 
ATOM   4079 C CB  . LEU B 1 134 ? 169.633 178.010 134.921 1.00 61.80  ? 134 LEU B CB  1 
ATOM   4080 C CG  . LEU B 1 134 ? 168.798 177.166 133.956 1.00 61.80  ? 134 LEU B CG  1 
ATOM   4081 C CD1 . LEU B 1 134 ? 168.673 177.851 132.608 1.00 61.80  ? 134 LEU B CD1 1 
ATOM   4082 C CD2 . LEU B 1 134 ? 169.407 175.783 133.797 1.00 61.80  ? 134 LEU B CD2 1 
ATOM   4083 N N   . CYS B 1 135 ? 167.619 179.042 137.219 1.00 62.57  ? 135 CYS B N   1 
ATOM   4084 C CA  . CYS B 1 135 ? 166.336 179.009 137.917 1.00 62.57  ? 135 CYS B CA  1 
ATOM   4085 C C   . CYS B 1 135 ? 165.594 180.326 137.745 1.00 62.57  ? 135 CYS B C   1 
ATOM   4086 O O   . CYS B 1 135 ? 164.388 180.346 137.474 1.00 62.57  ? 135 CYS B O   1 
ATOM   4087 C CB  . CYS B 1 135 ? 166.546 178.721 139.405 1.00 62.57  ? 135 CYS B CB  1 
ATOM   4088 S SG  . CYS B 1 135 ? 166.723 176.993 139.869 1.00 62.57  ? 135 CYS B SG  1 
ATOM   4089 N N   . ALA B 1 136 ? 166.305 181.443 137.906 1.00 62.34  ? 136 ALA B N   1 
ATOM   4090 C CA  . ALA B 1 136 ? 165.664 182.749 137.779 1.00 62.34  ? 136 ALA B CA  1 
ATOM   4091 C C   . ALA B 1 136 ? 165.209 183.023 136.351 1.00 62.34  ? 136 ALA B C   1 
ATOM   4092 O O   . ALA B 1 136 ? 164.256 183.780 136.143 1.00 62.34  ? 136 ALA B O   1 
ATOM   4093 C CB  . ALA B 1 136 ? 166.610 183.849 138.252 1.00 62.34  ? 136 ALA B CB  1 
ATOM   4094 N N   . VAL B 1 137 ? 165.873 182.427 135.360 1.00 64.09  ? 137 VAL B N   1 
ATOM   4095 C CA  . VAL B 1 137 ? 165.522 182.675 133.963 1.00 64.09  ? 137 VAL B CA  1 
ATOM   4096 C C   . VAL B 1 137 ? 164.505 181.671 133.417 1.00 64.09  ? 137 VAL B C   1 
ATOM   4097 O O   . VAL B 1 137 ? 163.873 181.942 132.385 1.00 64.09  ? 137 VAL B O   1 
ATOM   4098 C CB  . VAL B 1 137 ? 166.814 182.695 133.120 1.00 64.09  ? 137 VAL B CB  1 
ATOM   4099 C CG1 . VAL B 1 137 ? 166.533 182.847 131.635 1.00 64.09  ? 137 VAL B CG1 1 
ATOM   4100 C CG2 . VAL B 1 137 ? 167.719 183.822 133.587 1.00 64.09  ? 137 VAL B CG2 1 
ATOM   4101 N N   . ALA B 1 138 ? 164.279 180.555 134.113 1.00 67.52  ? 138 ALA B N   1 
ATOM   4102 C CA  . ALA B 1 138 ? 163.475 179.460 133.577 1.00 67.52  ? 138 ALA B CA  1 
ATOM   4103 C C   . ALA B 1 138 ? 162.076 179.928 133.195 1.00 67.52  ? 138 ALA B C   1 
ATOM   4104 O O   . ALA B 1 138 ? 161.490 180.802 133.839 1.00 67.52  ? 138 ALA B O   1 
ATOM   4105 C CB  . ALA B 1 138 ? 163.379 178.325 134.597 1.00 67.52  ? 138 ALA B CB  1 
ATOM   4106 N N   . TRP B 1 139 ? 161.541 179.331 132.125 1.00 72.05  ? 139 TRP B N   1 
ATOM   4107 C CA  . TRP B 1 139 ? 160.271 179.748 131.550 1.00 72.05  ? 139 TRP B CA  1 
ATOM   4108 C C   . TRP B 1 139 ? 159.171 178.697 131.611 1.00 72.05  ? 139 TRP B C   1 
ATOM   4109 O O   . TRP B 1 139 ? 158.010 179.039 131.365 1.00 72.05  ? 139 TRP B O   1 
ATOM   4110 C CB  . TRP B 1 139 ? 160.462 180.172 130.084 1.00 72.05  ? 139 TRP B CB  1 
ATOM   4111 C CG  . TRP B 1 139 ? 161.091 179.115 129.228 1.00 72.05  ? 139 TRP B CG  1 
ATOM   4112 C CD1 . TRP B 1 139 ? 160.450 178.114 128.559 1.00 72.05  ? 139 TRP B CD1 1 
ATOM   4113 C CD2 . TRP B 1 139 ? 162.486 178.954 128.948 1.00 72.05  ? 139 TRP B CD2 1 
ATOM   4114 N NE1 . TRP B 1 139 ? 161.359 177.339 127.881 1.00 72.05  ? 139 TRP B NE1 1 
ATOM   4115 C CE2 . TRP B 1 139 ? 162.616 177.834 128.104 1.00 72.05  ? 139 TRP B CE2 1 
ATOM   4116 C CE3 . TRP B 1 139 ? 163.638 179.647 129.331 1.00 72.05  ? 139 TRP B CE3 1 
ATOM   4117 C CZ2 . TRP B 1 139 ? 163.850 177.393 127.636 1.00 72.05  ? 139 TRP B CZ2 1 
ATOM   4118 C CZ3 . TRP B 1 139 ? 164.862 179.208 128.865 1.00 72.05  ? 139 TRP B CZ3 1 
ATOM   4119 C CH2 . TRP B 1 139 ? 164.959 178.092 128.027 1.00 72.05  ? 139 TRP B CH2 1 
ATOM   4120 N N   . ASP B 1 140 ? 159.488 177.441 131.918 1.00 75.44  ? 140 ASP B N   1 
ATOM   4121 C CA  . ASP B 1 140 ? 158.473 176.401 132.015 1.00 75.44  ? 140 ASP B CA  1 
ATOM   4122 C C   . ASP B 1 140 ? 158.884 175.408 133.096 1.00 75.44  ? 140 ASP B C   1 
ATOM   4123 O O   . ASP B 1 140 ? 159.918 175.564 133.750 1.00 75.44  ? 140 ASP B O   1 
ATOM   4124 C CB  . ASP B 1 140 ? 158.253 175.712 130.664 1.00 75.44  ? 140 ASP B CB  1 
ATOM   4125 C CG  . ASP B 1 140 ? 159.522 175.112 130.101 1.00 75.44  ? 140 ASP B CG  1 
ATOM   4126 O OD1 . ASP B 1 140 ? 160.610 175.658 130.373 1.00 75.44  ? 140 ASP B OD1 1 
ATOM   4127 O OD2 . ASP B 1 140 ? 159.432 174.096 129.381 1.00 75.44  ? 140 ASP B OD2 1 
ATOM   4128 N N   . GLU B 1 141 ? 158.051 174.383 133.285 1.00 78.24  ? 141 GLU B N   1 
ATOM   4129 C CA  . GLU B 1 141 ? 158.264 173.442 134.381 1.00 78.24  ? 141 GLU B CA  1 
ATOM   4130 C C   . GLU B 1 141 ? 159.526 172.611 134.177 1.00 78.24  ? 141 GLU B C   1 
ATOM   4131 O O   . GLU B 1 141 ? 160.284 172.383 135.127 1.00 78.24  ? 141 GLU B O   1 
ATOM   4132 C CB  . GLU B 1 141 ? 157.045 172.534 134.534 1.00 78.24  ? 141 GLU B CB  1 
ATOM   4133 C CG  . GLU B 1 141 ? 157.015 171.747 135.832 1.00 78.24  ? 141 GLU B CG  1 
ATOM   4134 C CD  . GLU B 1 141 ? 155.813 170.828 135.927 1.00 78.24  ? 141 GLU B CD  1 
ATOM   4135 O OE1 . GLU B 1 141 ? 154.829 171.057 135.193 1.00 78.24  ? 141 GLU B OE1 1 
ATOM   4136 O OE2 . GLU B 1 141 ? 155.851 169.878 136.737 1.00 78.24  ? 141 GLU B OE2 1 
ATOM   4137 N N   . ALA B 1 142 ? 159.762 172.141 132.950 1.00 73.23  ? 142 ALA B N   1 
ATOM   4138 C CA  . ALA B 1 142 ? 160.919 171.289 132.694 1.00 73.23  ? 142 ALA B CA  1 
ATOM   4139 C C   . ALA B 1 142 ? 162.224 172.031 132.950 1.00 73.23  ? 142 ALA B C   1 
ATOM   4140 O O   . ALA B 1 142 ? 163.154 171.479 133.553 1.00 73.23  ? 142 ALA B O   1 
ATOM   4141 C CB  . ALA B 1 142 ? 160.874 170.763 131.261 1.00 73.23  ? 142 ALA B CB  1 
ATOM   4142 N N   . THR B 1 143 ? 162.314 173.284 132.499 1.00 69.50  ? 143 THR B N   1 
ATOM   4143 C CA  . THR B 1 143 ? 163.529 174.062 132.719 1.00 69.50  ? 143 THR B CA  1 
ATOM   4144 C C   . THR B 1 143 ? 163.760 174.316 134.202 1.00 69.50  ? 143 THR B C   1 
ATOM   4145 O O   . THR B 1 143 ? 164.898 174.246 134.682 1.00 69.50  ? 143 THR B O   1 
ATOM   4146 C CB  . THR B 1 143 ? 163.452 175.380 131.953 1.00 69.50  ? 143 THR B CB  1 
ATOM   4147 O OG1 . THR B 1 143 ? 163.037 175.123 130.607 1.00 69.50  ? 143 THR B OG1 1 
ATOM   4148 C CG2 . THR B 1 143 ? 164.807 176.060 131.933 1.00 69.50  ? 143 THR B CG2 1 
ATOM   4149 N N   . LEU B 1 144 ? 162.692 174.611 134.946 1.00 66.78  ? 144 LEU B N   1 
ATOM   4150 C CA  . LEU B 1 144 ? 162.830 174.813 136.384 1.00 66.78  ? 144 LEU B CA  1 
ATOM   4151 C C   . LEU B 1 144 ? 163.303 173.542 137.075 1.00 66.78  ? 144 LEU B C   1 
ATOM   4152 O O   . LEU B 1 144 ? 164.156 173.594 137.968 1.00 66.78  ? 144 LEU B O   1 
ATOM   4153 C CB  . LEU B 1 144 ? 161.505 175.287 136.978 1.00 66.78  ? 144 LEU B CB  1 
ATOM   4154 C CG  . LEU B 1 144 ? 161.559 175.811 138.413 1.00 66.78  ? 144 LEU B CG  1 
ATOM   4155 C CD1 . LEU B 1 144 ? 162.510 176.984 138.513 1.00 66.78  ? 144 LEU B CD1 1 
ATOM   4156 C CD2 . LEU B 1 144 ? 160.175 176.203 138.887 1.00 66.78  ? 144 LEU B CD2 1 
ATOM   4157 N N   . VAL B 1 145 ? 162.765 172.388 136.673 1.00 65.25  ? 145 VAL B N   1 
ATOM   4158 C CA  . VAL B 1 145 ? 163.180 171.123 137.275 1.00 65.25  ? 145 VAL B CA  1 
ATOM   4159 C C   . VAL B 1 145 ? 164.648 170.843 136.977 1.00 65.25  ? 145 VAL B C   1 
ATOM   4160 O O   . VAL B 1 145 ? 165.408 170.419 137.859 1.00 65.25  ? 145 VAL B O   1 
ATOM   4161 C CB  . VAL B 1 145 ? 162.271 169.980 136.789 1.00 65.25  ? 145 VAL B CB  1 
ATOM   4162 C CG1 . VAL B 1 145 ? 162.929 168.635 137.033 1.00 65.25  ? 145 VAL B CG1 1 
ATOM   4163 C CG2 . VAL B 1 145 ? 160.920 170.050 137.481 1.00 65.25  ? 145 VAL B CG2 1 
ATOM   4164 N N   . ILE B 1 146 ? 165.074 171.078 135.734 1.00 63.94  ? 146 ILE B N   1 
ATOM   4165 C CA  . ILE B 1 146 ? 166.472 170.855 135.372 1.00 63.94  ? 146 ILE B CA  1 
ATOM   4166 C C   . ILE B 1 146 ? 167.386 171.774 136.173 1.00 63.94  ? 146 ILE B C   1 
ATOM   4167 O O   . ILE B 1 146 ? 168.442 171.352 136.668 1.00 63.94  ? 146 ILE B O   1 
ATOM   4168 C CB  . ILE B 1 146 ? 166.664 171.047 133.857 1.00 63.94  ? 146 ILE B CB  1 
ATOM   4169 C CG1 . ILE B 1 146 ? 165.906 169.968 133.085 1.00 63.94  ? 146 ILE B CG1 1 
ATOM   4170 C CG2 . ILE B 1 146 ? 168.137 171.022 133.497 1.00 63.94  ? 146 ILE B CG2 1 
ATOM   4171 C CD1 . ILE B 1 146 ? 166.027 170.097 131.588 1.00 63.94  ? 146 ILE B CD1 1 
ATOM   4172 N N   . ALA B 1 147 ? 166.999 173.042 136.314 1.00 61.20  ? 147 ALA B N   1 
ATOM   4173 C CA  . ALA B 1 147 ? 167.820 173.984 137.066 1.00 61.20  ? 147 ALA B CA  1 
ATOM   4174 C C   . ALA B 1 147 ? 167.897 173.604 138.540 1.00 61.20  ? 147 ALA B C   1 
ATOM   4175 O O   . ALA B 1 147 ? 168.953 173.749 139.167 1.00 61.20  ? 147 ALA B O   1 
ATOM   4176 C CB  . ALA B 1 147 ? 167.276 175.398 136.892 1.00 61.20  ? 147 ALA B CB  1 
ATOM   4177 N N   . ARG B 1 148 ? 166.792 173.123 139.115 1.00 59.71  ? 148 ARG B N   1 
ATOM   4178 C CA  . ARG B 1 148 ? 166.827 172.677 140.505 1.00 59.71  ? 148 ARG B CA  1 
ATOM   4179 C C   . ARG B 1 148 ? 167.723 171.455 140.674 1.00 59.71  ? 148 ARG B C   1 
ATOM   4180 O O   . ARG B 1 148 ? 168.453 171.346 141.667 1.00 59.71  ? 148 ARG B O   1 
ATOM   4181 C CB  . ARG B 1 148 ? 165.413 172.384 141.000 1.00 59.71  ? 148 ARG B CB  1 
ATOM   4182 C CG  . ARG B 1 148 ? 164.537 173.616 141.123 1.00 59.71  ? 148 ARG B CG  1 
ATOM   4183 C CD  . ARG B 1 148 ? 165.013 174.530 142.234 1.00 59.71  ? 148 ARG B CD  1 
ATOM   4184 N NE  . ARG B 1 148 ? 164.638 174.028 143.549 1.00 59.71  ? 148 ARG B NE  1 
ATOM   4185 C CZ  . ARG B 1 148 ? 165.038 174.560 144.695 1.00 59.71  ? 148 ARG B CZ  1 
ATOM   4186 N NH1 . ARG B 1 148 ? 165.824 175.621 144.727 1.00 59.71  ? 148 ARG B NH1 1 
ATOM   4187 N NH2 . ARG B 1 148 ? 164.635 174.014 145.838 1.00 59.71  ? 148 ARG B NH2 1 
ATOM   4188 N N   . LEU B 1 149 ? 167.687 170.527 139.713 1.00 58.02  ? 149 LEU B N   1 
ATOM   4189 C CA  . LEU B 1 149 ? 168.591 169.381 139.766 1.00 58.02  ? 149 LEU B CA  1 
ATOM   4190 C C   . LEU B 1 149 ? 170.048 169.827 139.712 1.00 58.02  ? 149 LEU B C   1 
ATOM   4191 O O   . LEU B 1 149 ? 170.899 169.295 140.437 1.00 58.02  ? 149 LEU B O   1 
ATOM   4192 C CB  . LEU B 1 149 ? 168.287 168.416 138.622 1.00 58.02  ? 149 LEU B CB  1 
ATOM   4193 C CG  . LEU B 1 149 ? 166.983 167.622 138.702 1.00 58.02  ? 149 LEU B CG  1 
ATOM   4194 C CD1 . LEU B 1 149 ? 166.688 166.946 137.376 1.00 58.02  ? 149 LEU B CD1 1 
ATOM   4195 C CD2 . LEU B 1 149 ? 167.048 166.596 139.815 1.00 58.02  ? 149 LEU B CD2 1 
ATOM   4196 N N   . SER B 1 150 ? 170.355 170.799 138.854 1.00 56.55  ? 150 SER B N   1 
ATOM   4197 C CA  . SER B 1 150 ? 171.725 171.298 138.764 1.00 56.55  ? 150 SER B CA  1 
ATOM   4198 C C   . SER B 1 150 ? 172.154 171.994 140.054 1.00 56.55  ? 150 SER B C   1 
ATOM   4199 O O   . SER B 1 150 ? 173.302 171.849 140.497 1.00 56.55  ? 150 SER B O   1 
ATOM   4200 C CB  . SER B 1 150 ? 171.853 172.235 137.567 1.00 56.55  ? 150 SER B CB  1 
ATOM   4201 O OG  . SER B 1 150 ? 171.471 171.583 136.371 1.00 56.55  ? 150 SER B OG  1 
ATOM   4202 N N   . GLN B 1 151 ? 171.249 172.766 140.665 1.00 55.83  ? 151 GLN B N   1 
ATOM   4203 C CA  . GLN B 1 151 ? 171.542 173.356 141.969 1.00 55.83  ? 151 GLN B CA  1 
ATOM   4204 C C   . GLN B 1 151 ? 171.854 172.282 142.998 1.00 55.83  ? 151 GLN B C   1 
ATOM   4205 O O   . GLN B 1 151 ? 172.791 172.423 143.793 1.00 55.83  ? 151 GLN B O   1 
ATOM   4206 C CB  . GLN B 1 151 ? 170.366 174.202 142.457 1.00 55.83  ? 151 GLN B CB  1 
ATOM   4207 C CG  . GLN B 1 151 ? 170.315 175.612 141.929 1.00 55.83  ? 151 GLN B CG  1 
ATOM   4208 C CD  . GLN B 1 151 ? 169.444 176.504 142.781 1.00 55.83  ? 151 GLN B CD  1 
ATOM   4209 O OE1 . GLN B 1 151 ? 169.639 177.716 142.835 1.00 55.83  ? 151 GLN B OE1 1 
ATOM   4210 N NE2 . GLN B 1 151 ? 168.478 175.907 143.460 1.00 55.83  ? 151 GLN B NE2 1 
ATOM   4211 N N   . GLY B 1 152 ? 171.063 171.209 143.010 1.00 54.04  ? 152 GLY B N   1 
ATOM   4212 C CA  . GLY B 1 152 ? 171.322 170.125 143.941 1.00 54.04  ? 152 GLY B CA  1 
ATOM   4213 C C   . GLY B 1 152 ? 172.670 169.473 143.710 1.00 54.04  ? 152 GLY B C   1 
ATOM   4214 O O   . GLY B 1 152 ? 173.378 169.141 144.661 1.00 54.04  ? 152 GLY B O   1 
ATOM   4215 N N   . VAL B 1 153 ? 173.044 169.285 142.444 1.00 52.27  ? 153 VAL B N   1 
ATOM   4216 C CA  . VAL B 1 153 ? 174.343 168.688 142.133 1.00 52.27  ? 153 VAL B CA  1 
ATOM   4217 C C   . VAL B 1 153 ? 175.472 169.574 142.647 1.00 52.27  ? 153 VAL B C   1 
ATOM   4218 O O   . VAL B 1 153 ? 176.427 169.096 143.273 1.00 52.27  ? 153 VAL B O   1 
ATOM   4219 C CB  . VAL B 1 153 ? 174.471 168.435 140.620 1.00 52.27  ? 153 VAL B CB  1 
ATOM   4220 C CG1 . VAL B 1 153 ? 175.911 168.133 140.254 1.00 52.27  ? 153 VAL B CG1 1 
ATOM   4221 C CG2 . VAL B 1 153 ? 173.564 167.299 140.195 1.00 52.27  ? 153 VAL B CG2 1 
ATOM   4222 N N   . GLY B 1 154 ? 175.377 170.880 142.393 1.00 49.41  ? 154 GLY B N   1 
ATOM   4223 C CA  . GLY B 1 154 ? 176.412 171.786 142.869 1.00 49.41  ? 154 GLY B CA  1 
ATOM   4224 C C   . GLY B 1 154 ? 176.514 171.816 144.382 1.00 49.41  ? 154 GLY B C   1 
ATOM   4225 O O   . GLY B 1 154 ? 177.615 171.796 144.944 1.00 49.41  ? 154 GLY B O   1 
ATOM   4226 N N   . SER B 1 155 ? 175.367 171.857 145.063 1.00 52.26  ? 155 SER B N   1 
ATOM   4227 C CA  . SER B 1 155 ? 175.367 171.849 146.521 1.00 52.26  ? 155 SER B CA  1 
ATOM   4228 C C   . SER B 1 155 ? 175.957 170.557 147.067 1.00 52.26  ? 155 SER B C   1 
ATOM   4229 O O   . SER B 1 155 ? 176.703 170.575 148.050 1.00 52.26  ? 155 SER B O   1 
ATOM   4230 C CB  . SER B 1 155 ? 173.948 172.052 147.045 1.00 52.26  ? 155 SER B CB  1 
ATOM   4231 O OG  . SER B 1 155 ? 173.952 172.314 148.434 1.00 52.26  ? 155 SER B OG  1 
ATOM   4232 N N   . ALA B 1 156 ? 175.627 169.420 146.451 1.00 51.20  ? 156 ALA B N   1 
ATOM   4233 C CA  . ALA B 1 156 ? 176.166 168.146 146.909 1.00 51.20  ? 156 ALA B CA  1 
ATOM   4234 C C   . ALA B 1 156 ? 177.667 168.056 146.682 1.00 51.20  ? 156 ALA B C   1 
ATOM   4235 O O   . ALA B 1 156 ? 178.370 167.405 147.459 1.00 51.20  ? 156 ALA B O   1 
ATOM   4236 C CB  . ALA B 1 156 ? 175.456 166.993 146.204 1.00 51.20  ? 156 ALA B CB  1 
ATOM   4237 N N   . ILE B 1 157 ? 178.171 168.679 145.618 1.00 51.21  ? 157 ILE B N   1 
ATOM   4238 C CA  . ILE B 1 157 ? 179.613 168.685 145.394 1.00 51.21  ? 157 ILE B CA  1 
ATOM   4239 C C   . ILE B 1 157 ? 180.316 169.566 146.422 1.00 51.21  ? 157 ILE B C   1 
ATOM   4240 O O   . ILE B 1 157 ? 181.378 169.206 146.942 1.00 51.21  ? 157 ILE B O   1 
ATOM   4241 C CB  . ILE B 1 157 ? 179.930 169.130 143.955 1.00 51.21  ? 157 ILE B CB  1 
ATOM   4242 C CG1 . ILE B 1 157 ? 179.555 168.031 142.964 1.00 51.21  ? 157 ILE B CG1 1 
ATOM   4243 C CG2 . ILE B 1 157 ? 181.398 169.474 143.809 1.00 51.21  ? 157 ILE B CG2 1 
ATOM   4244 C CD1 . ILE B 1 157 ? 179.821 168.403 141.528 1.00 51.21  ? 157 ILE B CD1 1 
ATOM   4245 N N   . ALA B 1 158 ? 179.737 170.725 146.742 1.00 49.26  ? 158 ALA B N   1 
ATOM   4246 C CA  . ALA B 1 158 ? 180.466 171.714 147.530 1.00 49.26  ? 158 ALA B CA  1 
ATOM   4247 C C   . ALA B 1 158 ? 180.272 171.592 149.039 1.00 49.26  ? 158 ALA B C   1 
ATOM   4248 O O   . ALA B 1 158 ? 181.165 171.990 149.793 1.00 49.26  ? 158 ALA B O   1 
ATOM   4249 C CB  . ALA B 1 158 ? 180.073 173.124 147.091 1.00 49.26  ? 158 ALA B CB  1 
ATOM   4250 N N   . SER B 1 159 ? 179.131 171.073 149.509 1.00 50.34  ? 159 SER B N   1 
ATOM   4251 C CA  . SER B 1 159 ? 178.861 171.078 150.948 1.00 50.34  ? 159 SER B CA  1 
ATOM   4252 C C   . SER B 1 159 ? 179.797 170.177 151.746 1.00 50.34  ? 159 SER B C   1 
ATOM   4253 O O   . SER B 1 159 ? 180.351 170.647 152.755 1.00 50.34  ? 159 SER B O   1 
ATOM   4254 C CB  . SER B 1 159 ? 177.392 170.727 151.200 1.00 50.34  ? 159 SER B CB  1 
ATOM   4255 O OG  . SER B 1 159 ? 176.545 171.801 150.835 1.00 50.34  ? 159 SER B OG  1 
ATOM   4256 N N   . PRO B 1 160 ? 180.007 168.901 151.394 1.00 50.99  ? 160 PRO B N   1 
ATOM   4257 C CA  . PRO B 1 160 ? 180.898 168.065 152.216 1.00 50.99  ? 160 PRO B CA  1 
ATOM   4258 C C   . PRO B 1 160 ? 182.330 168.552 152.246 1.00 50.99  ? 160 PRO B C   1 
ATOM   4259 O O   . PRO B 1 160 ? 183.072 168.189 153.164 1.00 50.99  ? 160 PRO B O   1 
ATOM   4260 C CB  . PRO B 1 160 ? 180.798 166.682 151.557 1.00 50.99  ? 160 PRO B CB  1 
ATOM   4261 C CG  . PRO B 1 160 ? 179.578 166.725 150.741 1.00 50.99  ? 160 PRO B CG  1 
ATOM   4262 C CD  . PRO B 1 160 ? 179.435 168.129 150.281 1.00 50.99  ? 160 PRO B CD  1 
ATOM   4263 N N   . THR B 1 161 ? 182.746 169.351 151.266 1.00 49.18  ? 161 THR B N   1 
ATOM   4264 C CA  . THR B 1 161 ? 184.101 169.878 151.242 1.00 49.18  ? 161 THR B CA  1 
ATOM   4265 C C   . THR B 1 161 ? 184.310 170.993 152.259 1.00 49.18  ? 161 THR B C   1 
ATOM   4266 O O   . THR B 1 161 ? 185.439 171.195 152.707 1.00 49.18  ? 161 THR B O   1 
ATOM   4267 C CB  . THR B 1 161 ? 184.438 170.375 149.834 1.00 49.18  ? 161 THR B CB  1 
ATOM   4268 O OG1 . THR B 1 161 ? 184.127 169.351 148.884 1.00 49.18  ? 161 THR B OG1 1 
ATOM   4269 C CG2 . THR B 1 161 ? 185.911 170.702 149.715 1.00 49.18  ? 161 THR B CG2 1 
ATOM   4270 N N   . GLY B 1 162 ? 183.252 171.704 152.651 1.00 47.68  ? 162 GLY B N   1 
ATOM   4271 C CA  . GLY B 1 162 ? 183.417 172.799 153.595 1.00 47.68  ? 162 GLY B CA  1 
ATOM   4272 C C   . GLY B 1 162 ? 183.849 172.345 154.977 1.00 47.68  ? 162 GLY B C   1 
ATOM   4273 O O   . GLY B 1 162 ? 184.744 172.939 155.584 1.00 47.68  ? 162 GLY B O   1 
ATOM   4274 N N   . LEU B 1 163 ? 183.223 171.289 155.498 1.00 47.70  ? 163 LEU B N   1 
ATOM   4275 C CA  . LEU B 1 163 ? 183.603 170.792 156.817 1.00 47.70  ? 163 LEU B CA  1 
ATOM   4276 C C   . LEU B 1 163 ? 184.999 170.178 156.793 1.00 47.70  ? 163 LEU B C   1 
ATOM   4277 O O   . LEU B 1 163 ? 185.778 170.343 157.742 1.00 47.70  ? 163 LEU B O   1 
ATOM   4278 C CB  . LEU B 1 163 ? 182.562 169.789 157.310 1.00 47.70  ? 163 LEU B CB  1 
ATOM   4279 C CG  . LEU B 1 163 ? 182.734 169.210 158.712 1.00 47.70  ? 163 LEU B CG  1 
ATOM   4280 C CD1 . LEU B 1 163 ? 182.664 170.305 159.755 1.00 47.70  ? 163 LEU B CD1 1 
ATOM   4281 C CD2 . LEU B 1 163 ? 181.660 168.173 158.970 1.00 47.70  ? 163 LEU B CD2 1 
ATOM   4282 N N   . ALA B 1 164 ? 185.339 169.480 155.708 1.00 47.68  ? 164 ALA B N   1 
ATOM   4283 C CA  . ALA B 1 164 ? 186.695 168.968 155.556 1.00 47.68  ? 164 ALA B CA  1 
ATOM   4284 C C   . ALA B 1 164 ? 187.706 170.103 155.488 1.00 47.68  ? 164 ALA B C   1 
ATOM   4285 O O   . ALA B 1 164 ? 188.818 169.981 156.009 1.00 47.68  ? 164 ALA B O   1 
ATOM   4286 C CB  . ALA B 1 164 ? 186.789 168.090 154.311 1.00 47.68  ? 164 ALA B CB  1 
ATOM   4287 N N   . LEU B 1 165 ? 187.345 171.211 154.839 1.00 47.91  ? 165 LEU B N   1 
ATOM   4288 C CA  . LEU B 1 165 ? 188.236 172.365 154.793 1.00 47.91  ? 165 LEU B CA  1 
ATOM   4289 C C   . LEU B 1 165 ? 188.399 172.988 156.172 1.00 47.91  ? 165 LEU B C   1 
ATOM   4290 O O   . LEU B 1 165 ? 189.490 173.449 156.523 1.00 47.91  ? 165 LEU B O   1 
ATOM   4291 C CB  . LEU B 1 165 ? 187.714 173.395 153.794 1.00 47.91  ? 165 LEU B CB  1 
ATOM   4292 C CG  . LEU B 1 165 ? 188.124 173.199 152.335 1.00 47.91  ? 165 LEU B CG  1 
ATOM   4293 C CD1 . LEU B 1 165 ? 187.293 174.080 151.428 1.00 47.91  ? 165 LEU B CD1 1 
ATOM   4294 C CD2 . LEU B 1 165 ? 189.599 173.495 152.156 1.00 47.91  ? 165 LEU B CD2 1 
ATOM   4295 N N   . VAL B 1 166 ? 187.327 173.015 156.966 1.00 47.94  ? 166 VAL B N   1 
ATOM   4296 C CA  . VAL B 1 166 ? 187.448 173.455 158.356 1.00 47.94  ? 166 VAL B CA  1 
ATOM   4297 C C   . VAL B 1 166 ? 188.446 172.578 159.100 1.00 47.94  ? 166 VAL B C   1 
ATOM   4298 O O   . VAL B 1 166 ? 189.316 173.070 159.827 1.00 47.94  ? 166 VAL B O   1 
ATOM   4299 C CB  . VAL B 1 166 ? 186.075 173.445 159.052 1.00 47.94  ? 166 VAL B CB  1 
ATOM   4300 C CG1 . VAL B 1 166 ? 186.249 173.547 160.553 1.00 47.94  ? 166 VAL B CG1 1 
ATOM   4301 C CG2 . VAL B 1 166 ? 185.220 174.583 158.559 1.00 47.94  ? 166 VAL B CG2 1 
ATOM   4302 N N   . ALA B 1 167 ? 188.333 171.262 158.924 1.00 49.56  ? 167 ALA B N   1 
ATOM   4303 C CA  . ALA B 1 167 ? 189.187 170.342 159.672 1.00 49.56  ? 167 ALA B CA  1 
ATOM   4304 C C   . ALA B 1 167 ? 190.642 170.416 159.220 1.00 49.56  ? 167 ALA B C   1 
ATOM   4305 O O   . ALA B 1 167 ? 191.555 170.308 160.045 1.00 49.56  ? 167 ALA B O   1 
ATOM   4306 C CB  . ALA B 1 167 ? 188.660 168.915 159.540 1.00 49.56  ? 167 ALA B CB  1 
ATOM   4307 N N   . THR B 1 168 ? 190.883 170.593 157.921 1.00 52.52  ? 168 THR B N   1 
ATOM   4308 C CA  . THR B 1 168 ? 192.237 170.500 157.385 1.00 52.52  ? 168 THR B CA  1 
ATOM   4309 C C   . THR B 1 168 ? 192.972 171.836 157.373 1.00 52.52  ? 168 THR B C   1 
ATOM   4310 O O   . THR B 1 168 ? 194.187 171.869 157.591 1.00 52.52  ? 168 THR B O   1 
ATOM   4311 C CB  . THR B 1 168 ? 192.208 169.924 155.966 1.00 52.52  ? 168 THR B CB  1 
ATOM   4312 O OG1 . THR B 1 168 ? 191.393 170.750 155.127 1.00 52.52  ? 168 THR B OG1 1 
ATOM   4313 C CG2 . THR B 1 168 ? 191.651 168.512 155.970 1.00 52.52  ? 168 THR B CG2 1 
ATOM   4314 N N   . THR B 1 169 ? 192.269 172.938 157.104 1.00 51.81  ? 169 THR B N   1 
ATOM   4315 C CA  . THR B 1 169 ? 192.926 174.239 157.027 1.00 51.81  ? 169 THR B CA  1 
ATOM   4316 C C   . THR B 1 169 ? 193.451 174.683 158.386 1.00 51.81  ? 169 THR B C   1 
ATOM   4317 O O   . THR B 1 169 ? 194.557 175.225 158.483 1.00 51.81  ? 169 THR B O   1 
ATOM   4318 C CB  . THR B 1 169 ? 191.958 175.278 156.465 1.00 51.81  ? 169 THR B CB  1 
ATOM   4319 O OG1 . THR B 1 169 ? 191.491 174.853 155.181 1.00 51.81  ? 169 THR B OG1 1 
ATOM   4320 C CG2 . THR B 1 169 ? 192.640 176.624 156.326 1.00 51.81  ? 169 THR B CG2 1 
ATOM   4321 N N   . PHE B 1 170 ? 192.675 174.461 159.445 1.00 52.99  ? 170 PHE B N   1 
ATOM   4322 C CA  . PHE B 1 170 ? 193.010 174.950 160.773 1.00 52.99  ? 170 PHE B CA  1 
ATOM   4323 C C   . PHE B 1 170 ? 193.461 173.798 161.654 1.00 52.99  ? 170 PHE B C   1 
ATOM   4324 O O   . PHE B 1 170 ? 192.694 172.846 161.854 1.00 52.99  ? 170 PHE B O   1 
ATOM   4325 C CB  . PHE B 1 170 ? 191.812 175.657 161.398 1.00 52.99  ? 170 PHE B CB  1 
ATOM   4326 C CG  . PHE B 1 170 ? 191.279 176.786 160.569 1.00 52.99  ? 170 PHE B CG  1 
ATOM   4327 C CD1 . PHE B 1 170 ? 191.977 177.974 160.466 1.00 52.99  ? 170 PHE B CD1 1 
ATOM   4328 C CD2 . PHE B 1 170 ? 190.084 176.658 159.888 1.00 52.99  ? 170 PHE B CD2 1 
ATOM   4329 C CE1 . PHE B 1 170 ? 191.491 179.013 159.702 1.00 52.99  ? 170 PHE B CE1 1 
ATOM   4330 C CE2 . PHE B 1 170 ? 189.593 177.693 159.123 1.00 52.99  ? 170 PHE B CE2 1 
ATOM   4331 C CZ  . PHE B 1 170 ? 190.297 178.871 159.030 1.00 52.99  ? 170 PHE B CZ  1 
ATOM   4332 N N   . PRO B 1 171 ? 194.675 173.835 162.195 1.00 56.17  ? 171 PRO B N   1 
ATOM   4333 C CA  . PRO B 1 171 ? 195.108 172.776 163.110 1.00 56.17  ? 171 PRO B CA  1 
ATOM   4334 C C   . PRO B 1 171 ? 194.311 172.807 164.403 1.00 56.17  ? 171 PRO B C   1 
ATOM   4335 O O   . PRO B 1 171 ? 193.722 173.821 164.782 1.00 56.17  ? 171 PRO B O   1 
ATOM   4336 C CB  . PRO B 1 171 ? 196.583 173.103 163.357 1.00 56.17  ? 171 PRO B CB  1 
ATOM   4337 C CG  . PRO B 1 171 ? 196.679 174.569 163.118 1.00 56.17  ? 171 PRO B CG  1 
ATOM   4338 C CD  . PRO B 1 171 ? 195.709 174.868 162.016 1.00 56.17  ? 171 PRO B CD  1 
ATOM   4339 N N   . LYS B 1 172 ? 194.291 171.659 165.077 1.00 55.22  ? 172 LYS B N   1 
ATOM   4340 C CA  . LYS B 1 172 ? 193.521 171.518 166.306 1.00 55.22  ? 172 LYS B CA  1 
ATOM   4341 C C   . LYS B 1 172 ? 193.983 172.528 167.349 1.00 55.22  ? 172 LYS B C   1 
ATOM   4342 O O   . LYS B 1 172 ? 195.183 172.702 167.575 1.00 55.22  ? 172 LYS B O   1 
ATOM   4343 C CB  . LYS B 1 172 ? 193.654 170.093 166.840 1.00 55.22  ? 172 LYS B CB  1 
ATOM   4344 C CG  . LYS B 1 172 ? 192.505 169.651 167.721 1.00 55.22  ? 172 LYS B CG  1 
ATOM   4345 C CD  . LYS B 1 172 ? 192.515 168.146 167.936 1.00 55.22  ? 172 LYS B CD  1 
ATOM   4346 C CE  . LYS B 1 172 ? 193.900 167.637 168.284 1.00 55.22  ? 172 LYS B CE  1 
ATOM   4347 N NZ  . LYS B 1 172 ? 194.199 167.797 169.729 1.00 55.22  ? 172 LYS B NZ  1 
ATOM   4348 N N   . GLY B 1 173 ? 193.022 173.201 167.976 1.00 55.04  ? 173 GLY B N   1 
ATOM   4349 C CA  . GLY B 1 173 ? 193.310 174.254 168.920 1.00 55.04  ? 173 GLY B CA  1 
ATOM   4350 C C   . GLY B 1 173 ? 192.259 175.343 168.875 1.00 55.04  ? 173 GLY B C   1 
ATOM   4351 O O   . GLY B 1 173 ? 191.122 175.117 168.456 1.00 55.04  ? 173 GLY B O   1 
ATOM   4352 N N   . PRO B 1 174 ? 192.617 176.550 169.320 1.00 54.97  ? 174 PRO B N   1 
ATOM   4353 C CA  . PRO B 1 174 ? 191.654 177.664 169.273 1.00 54.97  ? 174 PRO B CA  1 
ATOM   4354 C C   . PRO B 1 174 ? 191.182 178.013 167.871 1.00 54.97  ? 174 PRO B C   1 
ATOM   4355 O O   . PRO B 1 174 ? 190.026 178.429 167.698 1.00 54.97  ? 174 PRO B O   1 
ATOM   4356 C CB  . PRO B 1 174 ? 192.434 178.823 169.909 1.00 54.97  ? 174 PRO B CB  1 
ATOM   4357 C CG  . PRO B 1 174 ? 193.474 178.164 170.745 1.00 54.97  ? 174 PRO B CG  1 
ATOM   4358 C CD  . PRO B 1 174 ? 193.864 176.928 170.002 1.00 54.97  ? 174 PRO B CD  1 
ATOM   4359 N N   . ALA B 1 175 ? 192.046 177.862 166.863 1.00 53.49  ? 175 ALA B N   1 
ATOM   4360 C CA  . ALA B 1 175 ? 191.657 178.200 165.499 1.00 53.49  ? 175 ALA B CA  1 
ATOM   4361 C C   . ALA B 1 175 ? 190.511 177.322 165.016 1.00 53.49  ? 175 ALA B C   1 
ATOM   4362 O O   . ALA B 1 175 ? 189.552 177.817 164.413 1.00 53.49  ? 175 ALA B O   1 
ATOM   4363 C CB  . ALA B 1 175 ? 192.860 178.077 164.566 1.00 53.49  ? 175 ALA B CB  1 
ATOM   4364 N N   . ARG B 1 176 ? 190.583 176.017 165.285 1.00 49.96  ? 176 ARG B N   1 
ATOM   4365 C CA  . ARG B 1 176 ? 189.497 175.130 164.888 1.00 49.96  ? 176 ARG B CA  1 
ATOM   4366 C C   . ARG B 1 176 ? 188.220 175.421 165.663 1.00 49.96  ? 176 ARG B C   1 
ATOM   4367 O O   . ARG B 1 176 ? 187.123 175.293 165.110 1.00 49.96  ? 176 ARG B O   1 
ATOM   4368 C CB  . ARG B 1 176 ? 189.905 173.671 165.069 1.00 49.96  ? 176 ARG B CB  1 
ATOM   4369 C CG  . ARG B 1 176 ? 189.071 172.701 164.255 1.00 49.96  ? 176 ARG B CG  1 
ATOM   4370 C CD  . ARG B 1 176 ? 189.491 171.267 164.502 1.00 49.96  ? 176 ARG B CD  1 
ATOM   4371 N NE  . ARG B 1 176 ? 190.564 170.855 163.609 1.00 49.96  ? 176 ARG B NE  1 
ATOM   4372 C CZ  . ARG B 1 176 ? 190.989 169.607 163.476 1.00 49.96  ? 176 ARG B CZ  1 
ATOM   4373 N NH1 . ARG B 1 176 ? 190.450 168.617 164.166 1.00 49.96  ? 176 ARG B NH1 1 
ATOM   4374 N NH2 . ARG B 1 176 ? 191.981 169.346 162.631 1.00 49.96  ? 176 ARG B NH2 1 
ATOM   4375 N N   . ASN B 1 177 ? 188.336 175.815 166.933 1.00 51.21  ? 177 ASN B N   1 
ATOM   4376 C CA  . ASN B 1 177 ? 187.152 176.176 167.706 1.00 51.21  ? 177 ASN B CA  1 
ATOM   4377 C C   . ASN B 1 177 ? 186.446 177.381 167.094 1.00 51.21  ? 177 ASN B C   1 
ATOM   4378 O O   . ASN B 1 177 ? 185.221 177.374 166.907 1.00 51.21  ? 177 ASN B O   1 
ATOM   4379 C CB  . ASN B 1 177 ? 187.544 176.459 169.155 1.00 51.21  ? 177 ASN B CB  1 
ATOM   4380 C CG  . ASN B 1 177 ? 188.356 175.338 169.768 1.00 51.21  ? 177 ASN B CG  1 
ATOM   4381 O OD1 . ASN B 1 177 ? 188.562 174.298 169.150 1.00 51.21  ? 177 ASN B OD1 1 
ATOM   4382 N ND2 . ASN B 1 177 ? 188.826 175.548 170.990 1.00 51.21  ? 177 ASN B ND2 1 
ATOM   4383 N N   . ALA B 1 178 ? 187.210 178.424 166.758 1.00 48.77  ? 178 ALA B N   1 
ATOM   4384 C CA  . ALA B 1 178 ? 186.614 179.600 166.131 1.00 48.77  ? 178 ALA B CA  1 
ATOM   4385 C C   . ALA B 1 178 ? 186.026 179.262 164.766 1.00 48.77  ? 178 ALA B C   1 
ATOM   4386 O O   . ALA B 1 178 ? 184.943 179.748 164.406 1.00 48.77  ? 178 ALA B O   1 
ATOM   4387 C CB  . ALA B 1 178 ? 187.653 180.711 166.010 1.00 48.77  ? 178 ALA B CB  1 
ATOM   4388 N N   . ALA B 1 179 ? 186.728 178.433 163.989 1.00 48.00  ? 179 ALA B N   1 
ATOM   4389 C CA  . ALA B 1 179 ? 186.225 178.048 162.676 1.00 48.00  ? 179 ALA B CA  1 
ATOM   4390 C C   . ALA B 1 179 ? 184.908 177.291 162.788 1.00 48.00  ? 179 ALA B C   1 
ATOM   4391 O O   . ALA B 1 179 ? 183.979 177.535 162.012 1.00 48.00  ? 179 ALA B O   1 
ATOM   4392 C CB  . ALA B 1 179 ? 187.267 177.207 161.944 1.00 48.00  ? 179 ALA B CB  1 
ATOM   4393 N N   . THR B 1 180 ? 184.806 176.372 163.751 1.00 48.81  ? 180 THR B N   1 
ATOM   4394 C CA  . THR B 1 180 ? 183.562 175.632 163.933 1.00 48.81  ? 180 THR B CA  1 
ATOM   4395 C C   . THR B 1 180 ? 182.437 176.546 164.406 1.00 48.81  ? 180 THR B C   1 
ATOM   4396 O O   . THR B 1 180 ? 181.281 176.381 163.993 1.00 48.81  ? 180 THR B O   1 
ATOM   4397 C CB  . THR B 1 180 ? 183.771 174.483 164.916 1.00 48.81  ? 180 THR B CB  1 
ATOM   4398 O OG1 . THR B 1 180 ? 184.510 174.952 166.048 1.00 48.81  ? 180 THR B OG1 1 
ATOM   4399 C CG2 . THR B 1 180 ? 184.543 173.359 164.254 1.00 48.81  ? 180 THR B CG2 1 
ATOM   4400 N N   . ALA B 1 181 ? 182.751 177.519 165.264 1.00 47.13  ? 181 ALA B N   1 
ATOM   4401 C CA  . ALA B 1 181 ? 181.730 178.468 165.699 1.00 47.13  ? 181 ALA B CA  1 
ATOM   4402 C C   . ALA B 1 181 ? 181.175 179.259 164.520 1.00 47.13  ? 181 ALA B C   1 
ATOM   4403 O O   . ALA B 1 181 ? 179.956 179.425 164.384 1.00 47.13  ? 181 ALA B O   1 
ATOM   4404 C CB  . ALA B 1 181 ? 182.304 179.408 166.758 1.00 47.13  ? 181 ALA B CB  1 
ATOM   4405 N N   . VAL B 1 182 ? 182.056 179.747 163.645 1.00 49.08  ? 182 VAL B N   1 
ATOM   4406 C CA  . VAL B 1 182 ? 181.590 180.501 162.480 1.00 49.08  ? 182 VAL B CA  1 
ATOM   4407 C C   . VAL B 1 182 ? 180.806 179.597 161.531 1.00 49.08  ? 182 VAL B C   1 
ATOM   4408 O O   . VAL B 1 182 ? 179.771 179.998 160.973 1.00 49.08  ? 182 VAL B O   1 
ATOM   4409 C CB  . VAL B 1 182 ? 182.777 181.177 161.774 1.00 49.08  ? 182 VAL B CB  1 
ATOM   4410 C CG1 . VAL B 1 182 ? 182.305 181.924 160.543 1.00 49.08  ? 182 VAL B CG1 1 
ATOM   4411 C CG2 . VAL B 1 182 ? 183.487 182.119 162.726 1.00 49.08  ? 182 VAL B CG2 1 
ATOM   4412 N N   . PHE B 1 183 ? 181.291 178.369 161.329 1.00 50.56  ? 183 PHE B N   1 
ATOM   4413 C CA  . PHE B 1 183 ? 180.610 177.410 160.466 1.00 50.56  ? 183 PHE B CA  1 
ATOM   4414 C C   . PHE B 1 183 ? 179.193 177.139 160.954 1.00 50.56  ? 183 PHE B C   1 
ATOM   4415 O O   . PHE B 1 183 ? 178.270 176.984 160.147 1.00 50.56  ? 183 PHE B O   1 
ATOM   4416 C CB  . PHE B 1 183 ? 181.423 176.114 160.415 1.00 50.56  ? 183 PHE B CB  1 
ATOM   4417 C CG  . PHE B 1 183 ? 181.018 175.173 159.318 1.00 50.56  ? 183 PHE B CG  1 
ATOM   4418 C CD1 . PHE B 1 183 ? 181.550 175.299 158.049 1.00 50.56  ? 183 PHE B CD1 1 
ATOM   4419 C CD2 . PHE B 1 183 ? 180.125 174.146 159.562 1.00 50.56  ? 183 PHE B CD2 1 
ATOM   4420 C CE1 . PHE B 1 183 ? 181.187 174.433 157.045 1.00 50.56  ? 183 PHE B CE1 1 
ATOM   4421 C CE2 . PHE B 1 183 ? 179.760 173.277 158.559 1.00 50.56  ? 183 PHE B CE2 1 
ATOM   4422 C CZ  . PHE B 1 183 ? 180.292 173.421 157.300 1.00 50.56  ? 183 PHE B CZ  1 
ATOM   4423 N N   . ALA B 1 184 ? 179.003 177.075 162.272 1.00 50.47  ? 184 ALA B N   1 
ATOM   4424 C CA  . ALA B 1 184 ? 177.670 176.857 162.819 1.00 50.47  ? 184 ALA B CA  1 
ATOM   4425 C C   . ALA B 1 184 ? 176.805 178.112 162.768 1.00 50.47  ? 184 ALA B C   1 
ATOM   4426 O O   . ALA B 1 184 ? 175.585 178.007 162.607 1.00 50.47  ? 184 ALA B O   1 
ATOM   4427 C CB  . ALA B 1 184 ? 177.770 176.350 164.256 1.00 50.47  ? 184 ALA B CB  1 
ATOM   4428 N N   . ALA B 1 185 ? 177.404 179.296 162.914 1.00 52.29  ? 185 ALA B N   1 
ATOM   4429 C CA  . ALA B 1 185 ? 176.613 180.526 162.906 1.00 52.29  ? 185 ALA B CA  1 
ATOM   4430 C C   . ALA B 1 185 ? 176.069 180.840 161.516 1.00 52.29  ? 185 ALA B C   1 
ATOM   4431 O O   . ALA B 1 185 ? 174.960 181.387 161.382 1.00 52.29  ? 185 ALA B O   1 
ATOM   4432 C CB  . ALA B 1 185 ? 177.454 181.691 163.424 1.00 52.29  ? 185 ALA B CB  1 
ATOM   4433 N N   . MET B 1 186 ? 176.843 180.520 160.474 1.00 54.64  ? 186 MET B N   1 
ATOM   4434 C CA  . MET B 1 186 ? 176.436 180.891 159.120 1.00 54.64  ? 186 MET B CA  1 
ATOM   4435 C C   . MET B 1 186 ? 175.125 180.228 158.711 1.00 54.64  ? 186 MET B C   1 
ATOM   4436 O O   . MET B 1 186 ? 174.363 180.802 157.926 1.00 54.64  ? 186 MET B O   1 
ATOM   4437 C CB  . MET B 1 186 ? 177.541 180.545 158.125 1.00 54.64  ? 186 MET B CB  1 
ATOM   4438 C CG  . MET B 1 186 ? 178.790 181.391 158.282 1.00 54.64  ? 186 MET B CG  1 
ATOM   4439 S SD  . MET B 1 186 ? 178.695 182.962 157.411 1.00 54.64  ? 186 MET B SD  1 
ATOM   4440 C CE  . MET B 1 186 ? 179.543 182.557 155.891 1.00 54.64  ? 186 MET B CE  1 
ATOM   4441 N N   . THR B 1 187 ? 174.828 179.042 159.245 1.00 55.47  ? 187 THR B N   1 
ATOM   4442 C CA  . THR B 1 187 ? 173.588 178.356 158.891 1.00 55.47  ? 187 THR B CA  1 
ATOM   4443 C C   . THR B 1 187 ? 172.362 179.132 159.369 1.00 55.47  ? 187 THR B C   1 
ATOM   4444 O O   . THR B 1 187 ? 171.415 179.362 158.603 1.00 55.47  ? 187 THR B O   1 
ATOM   4445 C CB  . THR B 1 187 ? 173.594 176.945 159.477 1.00 55.47  ? 187 THR B CB  1 
ATOM   4446 O OG1 . THR B 1 187 ? 174.788 176.265 159.072 1.00 55.47  ? 187 THR B OG1 1 
ATOM   4447 C CG2 . THR B 1 187 ? 172.387 176.163 158.996 1.00 55.47  ? 187 THR B CG2 1 
ATOM   4448 N N   . ALA B 1 188 ? 172.359 179.540 160.641 1.00 54.27  ? 188 ALA B N   1 
ATOM   4449 C CA  . ALA B 1 188 ? 171.243 180.323 161.163 1.00 54.27  ? 188 ALA B CA  1 
ATOM   4450 C C   . ALA B 1 188 ? 171.153 181.676 160.471 1.00 54.27  ? 188 ALA B C   1 
ATOM   4451 O O   . ALA B 1 188 ? 170.048 182.171 160.189 1.00 54.27  ? 188 ALA B O   1 
ATOM   4452 C CB  . ALA B 1 188 ? 171.387 180.499 162.673 1.00 54.27  ? 188 ALA B CB  1 
ATOM   4453 N N   . ILE B 1 189 ? 172.307 182.295 160.198 1.00 54.60  ? 189 ILE B N   1 
ATOM   4454 C CA  . ILE B 1 189 ? 172.295 183.558 159.465 1.00 54.60  ? 189 ILE B CA  1 
ATOM   4455 C C   . ILE B 1 189 ? 171.600 183.379 158.122 1.00 54.60  ? 189 ILE B C   1 
ATOM   4456 O O   . ILE B 1 189 ? 170.751 184.190 157.732 1.00 54.60  ? 189 ILE B O   1 
ATOM   4457 C CB  . ILE B 1 189 ? 173.726 184.099 159.295 1.00 54.60  ? 189 ILE B CB  1 
ATOM   4458 C CG1 . ILE B 1 189 ? 174.290 184.554 160.639 1.00 54.60  ? 189 ILE B CG1 1 
ATOM   4459 C CG2 . ILE B 1 189 ? 173.744 185.249 158.310 1.00 54.60  ? 189 ILE B CG2 1 
ATOM   4460 C CD1 . ILE B 1 189 ? 175.671 185.153 160.544 1.00 54.60  ? 189 ILE B CD1 1 
ATOM   4461 N N   . GLY B 1 190 ? 171.931 182.301 157.408 1.00 55.92  ? 190 GLY B N   1 
ATOM   4462 C CA  . GLY B 1 190 ? 171.297 182.048 156.126 1.00 55.92  ? 190 GLY B CA  1 
ATOM   4463 C C   . GLY B 1 190 ? 169.805 181.804 156.239 1.00 55.92  ? 190 GLY B C   1 
ATOM   4464 O O   . GLY B 1 190 ? 169.029 182.281 155.410 1.00 55.92  ? 190 GLY B O   1 
ATOM   4465 N N   . SER B 1 191 ? 169.384 181.056 157.262 1.00 57.89  ? 191 SER B N   1 
ATOM   4466 C CA  . SER B 1 191 ? 167.956 180.788 157.439 1.00 57.89  ? 191 SER B CA  1 
ATOM   4467 C C   . SER B 1 191 ? 167.167 182.082 157.611 1.00 57.89  ? 191 SER B C   1 
ATOM   4468 O O   . SER B 1 191 ? 166.159 182.318 156.924 1.00 57.89  ? 191 SER B O   1 
ATOM   4469 C CB  . SER B 1 191 ? 167.735 179.883 158.651 1.00 57.89  ? 191 SER B CB  1 
ATOM   4470 O OG  . SER B 1 191 ? 168.628 178.790 158.660 1.00 57.89  ? 191 SER B OG  1 
ATOM   4471 N N   . VAL B 1 192 ? 167.611 182.935 158.535 1.00 59.35  ? 192 VAL B N   1 
ATOM   4472 C CA  . VAL B 1 192 ? 166.862 184.160 158.807 1.00 59.35  ? 192 VAL B CA  1 
ATOM   4473 C C   . VAL B 1 192 ? 166.949 185.125 157.630 1.00 59.35  ? 192 VAL B C   1 
ATOM   4474 O O   . VAL B 1 192 ? 165.976 185.824 157.315 1.00 59.35  ? 192 VAL B O   1 
ATOM   4475 C CB  . VAL B 1 192 ? 167.335 184.798 160.121 1.00 59.35  ? 192 VAL B CB  1 
ATOM   4476 C CG1 . VAL B 1 192 ? 166.361 185.870 160.555 1.00 59.35  ? 192 VAL B CG1 1 
ATOM   4477 C CG2 . VAL B 1 192 ? 167.409 183.732 161.183 1.00 59.35  ? 192 VAL B CG2 1 
ATOM   4478 N N   . MET B 1 193 ? 168.102 185.183 156.958 1.00 61.82  ? 193 MET B N   1 
ATOM   4479 C CA  . MET B 1 193 ? 168.204 186.002 155.755 1.00 61.82  ? 193 MET B CA  1 
ATOM   4480 C C   . MET B 1 193 ? 167.225 185.530 154.690 1.00 61.82  ? 193 MET B C   1 
ATOM   4481 O O   . MET B 1 193 ? 166.613 186.348 153.994 1.00 61.82  ? 193 MET B O   1 
ATOM   4482 C CB  . MET B 1 193 ? 169.633 185.971 155.216 1.00 61.82  ? 193 MET B CB  1 
ATOM   4483 C CG  . MET B 1 193 ? 170.142 187.312 154.729 1.00 61.82  ? 193 MET B CG  1 
ATOM   4484 S SD  . MET B 1 193 ? 171.715 187.178 153.863 1.00 61.82  ? 193 MET B SD  1 
ATOM   4485 C CE  . MET B 1 193 ? 172.859 187.207 155.238 1.00 61.82  ? 193 MET B CE  1 
ATOM   4486 N N   . GLY B 1 194 ? 167.069 184.214 154.544 1.00 60.42  ? 194 GLY B N   1 
ATOM   4487 C CA  . GLY B 1 194 ? 166.112 183.695 153.584 1.00 60.42  ? 194 GLY B CA  1 
ATOM   4488 C C   . GLY B 1 194 ? 164.688 184.089 153.914 1.00 60.42  ? 194 GLY B C   1 
ATOM   4489 O O   . GLY B 1 194 ? 163.930 184.501 153.032 1.00 60.42  ? 194 GLY B O   1 
ATOM   4490 N N   . LEU B 1 195 ? 164.303 183.974 155.188 1.00 61.65  ? 195 LEU B N   1 
ATOM   4491 C CA  . LEU B 1 195 ? 162.962 184.412 155.578 1.00 61.65  ? 195 LEU B CA  1 
ATOM   4492 C C   . LEU B 1 195 ? 162.753 185.893 155.282 1.00 61.65  ? 195 LEU B C   1 
ATOM   4493 O O   . LEU B 1 195 ? 161.721 186.286 154.725 1.00 61.65  ? 195 LEU B O   1 
ATOM   4494 C CB  . LEU B 1 195 ? 162.696 184.131 157.057 1.00 61.65  ? 195 LEU B CB  1 
ATOM   4495 C CG  . LEU B 1 195 ? 162.340 182.706 157.463 1.00 61.65  ? 195 LEU B CG  1 
ATOM   4496 C CD1 . LEU B 1 195 ? 162.223 182.607 158.969 1.00 61.65  ? 195 LEU B CD1 1 
ATOM   4497 C CD2 . LEU B 1 195 ? 161.038 182.302 156.805 1.00 61.65  ? 195 LEU B CD2 1 
ATOM   4498 N N   . VAL B 1 196 ? 163.729 186.731 155.640 1.00 63.80  ? 196 VAL B N   1 
ATOM   4499 C CA  . VAL B 1 196 ? 163.574 188.174 155.453 1.00 63.80  ? 196 VAL B CA  1 
ATOM   4500 C C   . VAL B 1 196 ? 163.457 188.513 153.972 1.00 63.80  ? 196 VAL B C   1 
ATOM   4501 O O   . VAL B 1 196 ? 162.591 189.294 153.563 1.00 63.80  ? 196 VAL B O   1 
ATOM   4502 C CB  . VAL B 1 196 ? 164.738 188.933 156.114 1.00 63.80  ? 196 VAL B CB  1 
ATOM   4503 C CG1 . VAL B 1 196 ? 164.725 190.387 155.689 1.00 63.80  ? 196 VAL B CG1 1 
ATOM   4504 C CG2 . VAL B 1 196 ? 164.650 188.825 157.623 1.00 63.80  ? 196 VAL B CG2 1 
ATOM   4505 N N   . VAL B 1 197 ? 164.326 187.927 153.144 1.00 66.04  ? 197 VAL B N   1 
ATOM   4506 C CA  . VAL B 1 197 ? 164.309 188.222 151.713 1.00 66.04  ? 197 VAL B CA  1 
ATOM   4507 C C   . VAL B 1 197 ? 163.014 187.735 151.075 1.00 66.04  ? 197 VAL B C   1 
ATOM   4508 O O   . VAL B 1 197 ? 162.396 188.445 150.270 1.00 66.04  ? 197 VAL B O   1 
ATOM   4509 C CB  . VAL B 1 197 ? 165.546 187.609 151.030 1.00 66.04  ? 197 VAL B CB  1 
ATOM   4510 C CG1 . VAL B 1 197 ? 165.334 187.506 149.531 1.00 66.04  ? 197 VAL B CG1 1 
ATOM   4511 C CG2 . VAL B 1 197 ? 166.781 188.436 151.338 1.00 66.04  ? 197 VAL B CG2 1 
ATOM   4512 N N   . GLY B 1 198 ? 162.583 186.518 151.415 1.00 67.95  ? 198 GLY B N   1 
ATOM   4513 C CA  . GLY B 1 198 ? 161.347 186.002 150.853 1.00 67.95  ? 198 GLY B CA  1 
ATOM   4514 C C   . GLY B 1 198 ? 160.137 186.825 151.249 1.00 67.95  ? 198 GLY B C   1 
ATOM   4515 O O   . GLY B 1 198 ? 159.232 187.041 150.440 1.00 67.95  ? 198 GLY B O   1 
ATOM   4516 N N   . GLY B 1 199 ? 160.099 187.287 152.499 1.00 69.83  ? 199 GLY B N   1 
ATOM   4517 C CA  . GLY B 1 199 ? 159.010 188.153 152.915 1.00 69.83  ? 199 GLY B CA  1 
ATOM   4518 C C   . GLY B 1 199 ? 159.034 189.497 152.214 1.00 69.83  ? 199 GLY B C   1 
ATOM   4519 O O   . GLY B 1 199 ? 157.991 190.005 151.792 1.00 69.83  ? 199 GLY B O   1 
ATOM   4520 N N   . ALA B 1 200 ? 160.221 190.092 152.078 1.00 69.07  ? 200 ALA B N   1 
ATOM   4521 C CA  . ALA B 1 200 ? 160.323 191.408 151.458 1.00 69.07  ? 200 ALA B CA  1 
ATOM   4522 C C   . ALA B 1 200 ? 159.943 191.364 149.984 1.00 69.07  ? 200 ALA B C   1 
ATOM   4523 O O   . ALA B 1 200 ? 159.260 192.267 149.489 1.00 69.07  ? 200 ALA B O   1 
ATOM   4524 C CB  . ALA B 1 200 ? 161.737 191.961 151.629 1.00 69.07  ? 200 ALA B CB  1 
ATOM   4525 N N   . LEU B 1 201 ? 160.370 190.324 149.264 1.00 72.89  ? 201 LEU B N   1 
ATOM   4526 C CA  . LEU B 1 201 ? 160.150 190.245 147.825 1.00 72.89  ? 201 LEU B CA  1 
ATOM   4527 C C   . LEU B 1 201 ? 158.884 189.480 147.459 1.00 72.89  ? 201 LEU B C   1 
ATOM   4528 O O   . LEU B 1 201 ? 158.818 188.878 146.380 1.00 72.89  ? 201 LEU B O   1 
ATOM   4529 C CB  . LEU B 1 201 ? 161.367 189.618 147.145 1.00 72.89  ? 201 LEU B CB  1 
ATOM   4530 C CG  . LEU B 1 201 ? 162.586 190.532 147.023 1.00 72.89  ? 201 LEU B CG  1 
ATOM   4531 C CD1 . LEU B 1 201 ? 163.852 189.715 146.848 1.00 72.89  ? 201 LEU B CD1 1 
ATOM   4532 C CD2 . LEU B 1 201 ? 162.406 191.502 145.872 1.00 72.89  ? 201 LEU B CD2 1 
ATOM   4533 N N   . THR B 1 202 ? 157.874 189.487 148.328 1.00 78.53  ? 202 THR B N   1 
ATOM   4534 C CA  . THR B 1 202 ? 156.614 188.815 148.038 1.00 78.53  ? 202 THR B CA  1 
ATOM   4535 C C   . THR B 1 202 ? 155.676 189.659 147.187 1.00 78.53  ? 202 THR B C   1 
ATOM   4536 O O   . THR B 1 202 ? 154.636 189.154 146.753 1.00 78.53  ? 202 THR B O   1 
ATOM   4537 C CB  . THR B 1 202 ? 155.905 188.432 149.340 1.00 78.53  ? 202 THR B CB  1 
ATOM   4538 O OG1 . THR B 1 202 ? 154.927 187.418 149.076 1.00 78.53  ? 202 THR B OG1 1 
ATOM   4539 C CG2 . THR B 1 202 ? 155.215 189.644 149.949 1.00 78.53  ? 202 THR B CG2 1 
ATOM   4540 N N   . GLU B 1 203 ? 156.017 190.921 146.937 1.00 82.65  ? 203 GLU B N   1 
ATOM   4541 C CA  . GLU B 1 203 ? 155.147 191.825 146.202 1.00 82.65  ? 203 GLU B CA  1 
ATOM   4542 C C   . GLU B 1 203 ? 155.529 191.973 144.735 1.00 82.65  ? 203 GLU B C   1 
ATOM   4543 O O   . GLU B 1 203 ? 154.649 192.230 143.907 1.00 82.65  ? 203 GLU B O   1 
ATOM   4544 C CB  . GLU B 1 203 ? 155.148 193.206 146.871 1.00 82.65  ? 203 GLU B CB  1 
ATOM   4545 C CG  . GLU B 1 203 ? 154.238 194.239 146.223 1.00 82.65  ? 203 GLU B CG  1 
ATOM   4546 C CD  . GLU B 1 203 ? 152.769 193.876 146.323 1.00 82.65  ? 203 GLU B CD  1 
ATOM   4547 O OE1 . GLU B 1 203 ? 152.395 193.142 147.261 1.00 82.65  ? 203 GLU B OE1 1 
ATOM   4548 O OE2 . GLU B 1 203 ? 151.987 194.327 145.460 1.00 82.65  ? 203 GLU B OE2 1 
ATOM   4549 N N   . VAL B 1 204 ? 156.804 191.796 144.388 1.00 80.01  ? 204 VAL B N   1 
ATOM   4550 C CA  . VAL B 1 204 ? 157.257 192.069 143.030 1.00 80.01  ? 204 VAL B CA  1 
ATOM   4551 C C   . VAL B 1 204 ? 157.151 190.816 142.171 1.00 80.01  ? 204 VAL B C   1 
ATOM   4552 O O   . VAL B 1 204 ? 156.347 190.762 141.234 1.00 80.01  ? 204 VAL B O   1 
ATOM   4553 C CB  . VAL B 1 204 ? 158.700 192.602 143.029 1.00 80.01  ? 204 VAL B CB  1 
ATOM   4554 C CG1 . VAL B 1 204 ? 159.194 192.784 141.603 1.00 80.01  ? 204 VAL B CG1 1 
ATOM   4555 C CG2 . VAL B 1 204 ? 158.788 193.904 143.805 1.00 80.01  ? 204 VAL B CG2 1 
ATOM   4556 N N   . SER B 1 205 ? 157.938 189.793 142.503 1.00 73.81  ? 205 SER B N   1 
ATOM   4557 C CA  . SER B 1 205 ? 157.999 188.573 141.706 1.00 73.81  ? 205 SER B CA  1 
ATOM   4558 C C   . SER B 1 205 ? 158.869 187.527 142.388 1.00 73.81  ? 205 SER B C   1 
ATOM   4559 O O   . SER B 1 205 ? 159.754 187.868 143.178 1.00 73.81  ? 205 SER B O   1 
ATOM   4560 C CB  . SER B 1 205 ? 158.542 188.867 140.305 1.00 73.81  ? 205 SER B CB  1 
ATOM   4561 O OG  . SER B 1 205 ? 158.241 187.812 139.410 1.00 73.81  ? 205 SER B OG  1 
ATOM   4562 N N   . TRP B 1 206 ? 158.625 186.250 142.093 1.00 70.99  ? 206 TRP B N   1 
ATOM   4563 C CA  . TRP B 1 206 ? 159.469 185.197 142.644 1.00 70.99  ? 206 TRP B CA  1 
ATOM   4564 C C   . TRP B 1 206 ? 160.803 185.098 141.917 1.00 70.99  ? 206 TRP B C   1 
ATOM   4565 O O   . TRP B 1 206 ? 161.790 184.644 142.505 1.00 70.99  ? 206 TRP B O   1 
ATOM   4566 C CB  . TRP B 1 206 ? 158.745 183.853 142.593 1.00 70.99  ? 206 TRP B CB  1 
ATOM   4567 C CG  . TRP B 1 206 ? 158.463 183.366 141.211 1.00 70.99  ? 206 TRP B CG  1 
ATOM   4568 C CD1 . TRP B 1 206 ? 157.343 183.603 140.475 1.00 70.99  ? 206 TRP B CD1 1 
ATOM   4569 C CD2 . TRP B 1 206 ? 159.314 182.550 140.398 1.00 70.99  ? 206 TRP B CD2 1 
ATOM   4570 N NE1 . TRP B 1 206 ? 157.441 182.985 139.254 1.00 70.99  ? 206 TRP B NE1 1 
ATOM   4571 C CE2 . TRP B 1 206 ? 158.642 182.331 139.181 1.00 70.99  ? 206 TRP B CE2 1 
ATOM   4572 C CE3 . TRP B 1 206 ? 160.578 181.981 140.581 1.00 70.99  ? 206 TRP B CE3 1 
ATOM   4573 C CZ2 . TRP B 1 206 ? 159.190 181.572 138.152 1.00 70.99  ? 206 TRP B CZ2 1 
ATOM   4574 C CZ3 . TRP B 1 206 ? 161.120 181.228 139.558 1.00 70.99  ? 206 TRP B CZ3 1 
ATOM   4575 C CH2 . TRP B 1 206 ? 160.427 181.030 138.360 1.00 70.99  ? 206 TRP B CH2 1 
ATOM   4576 N N   . ARG B 1 207 ? 160.852 185.508 140.648 1.00 69.59  ? 207 ARG B N   1 
ATOM   4577 C CA  . ARG B 1 207 ? 162.094 185.444 139.888 1.00 69.59  ? 207 ARG B CA  1 
ATOM   4578 C C   . ARG B 1 207 ? 163.167 186.360 140.456 1.00 69.59  ? 207 ARG B C   1 
ATOM   4579 O O   . ARG B 1 207 ? 164.356 186.104 140.247 1.00 69.59  ? 207 ARG B O   1 
ATOM   4580 C CB  . ARG B 1 207 ? 161.834 185.799 138.425 1.00 69.59  ? 207 ARG B CB  1 
ATOM   4581 C CG  . ARG B 1 207 ? 160.923 184.830 137.697 1.00 69.59  ? 207 ARG B CG  1 
ATOM   4582 C CD  . ARG B 1 207 ? 160.700 185.275 136.265 1.00 69.59  ? 207 ARG B CD  1 
ATOM   4583 N NE  . ARG B 1 207 ? 159.663 184.496 135.601 1.00 69.59  ? 207 ARG B NE  1 
ATOM   4584 C CZ  . ARG B 1 207 ? 159.898 183.471 134.794 1.00 69.59  ? 207 ARG B CZ  1 
ATOM   4585 N NH1 . ARG B 1 207 ? 161.129 183.072 134.525 1.00 69.59  ? 207 ARG B NH1 1 
ATOM   4586 N NH2 . ARG B 1 207 ? 158.872 182.832 134.241 1.00 69.59  ? 207 ARG B NH2 1 
ATOM   4587 N N   . TRP B 1 208 ? 162.779 187.422 141.159 1.00 69.97  ? 208 TRP B N   1 
ATOM   4588 C CA  . TRP B 1 208 ? 163.748 188.314 141.778 1.00 69.97  ? 208 TRP B CA  1 
ATOM   4589 C C   . TRP B 1 208 ? 164.342 187.742 143.055 1.00 69.97  ? 208 TRP B C   1 
ATOM   4590 O O   . TRP B 1 208 ? 165.360 188.255 143.528 1.00 69.97  ? 208 TRP B O   1 
ATOM   4591 C CB  . TRP B 1 208 ? 163.103 189.669 142.077 1.00 69.97  ? 208 TRP B CB  1 
ATOM   4592 C CG  . TRP B 1 208 ? 162.864 190.482 140.852 1.00 69.97  ? 208 TRP B CG  1 
ATOM   4593 C CD1 . TRP B 1 208 ? 161.677 190.670 140.214 1.00 69.97  ? 208 TRP B CD1 1 
ATOM   4594 C CD2 . TRP B 1 208 ? 163.845 191.201 140.099 1.00 69.97  ? 208 TRP B CD2 1 
ATOM   4595 N NE1 . TRP B 1 208 ? 161.853 191.472 139.114 1.00 69.97  ? 208 TRP B NE1 1 
ATOM   4596 C CE2 . TRP B 1 208 ? 163.177 191.810 139.020 1.00 69.97  ? 208 TRP B CE2 1 
ATOM   4597 C CE3 . TRP B 1 208 ? 165.223 191.392 140.233 1.00 69.97  ? 208 TRP B CE3 1 
ATOM   4598 C CZ2 . TRP B 1 208 ? 163.839 192.598 138.083 1.00 69.97  ? 208 TRP B CZ2 1 
ATOM   4599 C CZ3 . TRP B 1 208 ? 165.878 192.173 139.303 1.00 69.97  ? 208 TRP B CZ3 1 
ATOM   4600 C CH2 . TRP B 1 208 ? 165.186 192.767 138.241 1.00 69.97  ? 208 TRP B CH2 1 
ATOM   4601 N N   . ALA B 1 209 ? 163.733 186.702 143.622 1.00 66.44  ? 209 ALA B N   1 
ATOM   4602 C CA  . ALA B 1 209 ? 164.259 186.104 144.841 1.00 66.44  ? 209 ALA B CA  1 
ATOM   4603 C C   . ALA B 1 209 ? 165.359 185.092 144.552 1.00 66.44  ? 209 ALA B C   1 
ATOM   4604 O O   . ALA B 1 209 ? 166.235 184.880 145.397 1.00 66.44  ? 209 ALA B O   1 
ATOM   4605 C CB  . ALA B 1 209 ? 163.127 185.445 145.627 1.00 66.44  ? 209 ALA B CB  1 
ATOM   4606 N N   . PHE B 1 210 ? 165.332 184.462 143.378 1.00 62.74  ? 210 PHE B N   1 
ATOM   4607 C CA  . PHE B 1 210 ? 166.374 183.516 143.002 1.00 62.74  ? 210 PHE B CA  1 
ATOM   4608 C C   . PHE B 1 210 ? 167.676 184.199 142.609 1.00 62.74  ? 210 PHE B C   1 
ATOM   4609 O O   . PHE B 1 210 ? 168.733 183.565 142.666 1.00 62.74  ? 210 PHE B O   1 
ATOM   4610 C CB  . PHE B 1 210 ? 165.896 182.634 141.849 1.00 62.74  ? 210 PHE B CB  1 
ATOM   4611 C CG  . PHE B 1 210 ? 165.171 181.399 142.290 1.00 62.74  ? 210 PHE B CG  1 
ATOM   4612 C CD1 . PHE B 1 210 ? 165.688 180.599 143.291 1.00 62.74  ? 210 PHE B CD1 1 
ATOM   4613 C CD2 . PHE B 1 210 ? 163.978 181.032 141.698 1.00 62.74  ? 210 PHE B CD2 1 
ATOM   4614 C CE1 . PHE B 1 210 ? 165.025 179.460 143.697 1.00 62.74  ? 210 PHE B CE1 1 
ATOM   4615 C CE2 . PHE B 1 210 ? 163.312 179.893 142.100 1.00 62.74  ? 210 PHE B CE2 1 
ATOM   4616 C CZ  . PHE B 1 210 ? 163.836 179.106 143.101 1.00 62.74  ? 210 PHE B CZ  1 
ATOM   4617 N N   . LEU B 1 211 ? 167.625 185.470 142.215 1.00 63.60  ? 211 LEU B N   1 
ATOM   4618 C CA  . LEU B 1 211 ? 168.821 186.189 141.800 1.00 63.60  ? 211 LEU B CA  1 
ATOM   4619 C C   . LEU B 1 211 ? 169.691 186.624 142.970 1.00 63.60  ? 211 LEU B C   1 
ATOM   4620 O O   . LEU B 1 211 ? 170.861 186.956 142.755 1.00 63.60  ? 211 LEU B O   1 
ATOM   4621 C CB  . LEU B 1 211 ? 168.435 187.416 140.971 1.00 63.60  ? 211 LEU B CB  1 
ATOM   4622 C CG  . LEU B 1 211 ? 168.123 187.181 139.493 1.00 63.60  ? 211 LEU B CG  1 
ATOM   4623 C CD1 . LEU B 1 211 ? 167.839 188.497 138.797 1.00 63.60  ? 211 LEU B CD1 1 
ATOM   4624 C CD2 . LEU B 1 211 ? 169.261 186.450 138.811 1.00 63.60  ? 211 LEU B CD2 1 
ATOM   4625 N N   . VAL B 1 212 ? 169.158 186.625 144.194 1.00 64.58  ? 212 VAL B N   1 
ATOM   4626 C CA  . VAL B 1 212 ? 169.935 187.077 145.344 1.00 64.58  ? 212 VAL B CA  1 
ATOM   4627 C C   . VAL B 1 212 ? 171.130 186.165 145.591 1.00 64.58  ? 212 VAL B C   1 
ATOM   4628 O O   . VAL B 1 212 ? 172.136 186.592 146.170 1.00 64.58  ? 212 VAL B O   1 
ATOM   4629 C CB  . VAL B 1 212 ? 169.030 187.175 146.586 1.00 64.58  ? 212 VAL B CB  1 
ATOM   4630 C CG1 . VAL B 1 212 ? 169.740 187.912 147.707 1.00 64.58  ? 212 VAL B CG1 1 
ATOM   4631 C CG2 . VAL B 1 212 ? 167.731 187.873 146.231 1.00 64.58  ? 212 VAL B CG2 1 
ATOM   4632 N N   . ASN B 1 213 ? 171.051 184.904 145.164 1.00 62.50  ? 213 ASN B N   1 
ATOM   4633 C CA  . ASN B 1 213 ? 172.190 184.005 145.300 1.00 62.50  ? 213 ASN B CA  1 
ATOM   4634 C C   . ASN B 1 213 ? 173.330 184.365 144.357 1.00 62.50  ? 213 ASN B C   1 
ATOM   4635 O O   . ASN B 1 213 ? 174.472 183.970 144.611 1.00 62.50  ? 213 ASN B O   1 
ATOM   4636 C CB  . ASN B 1 213 ? 171.760 182.560 145.049 1.00 62.50  ? 213 ASN B CB  1 
ATOM   4637 C CG  . ASN B 1 213 ? 170.537 182.168 145.848 1.00 62.50  ? 213 ASN B CG  1 
ATOM   4638 O OD1 . ASN B 1 213 ? 170.375 182.577 146.996 1.00 62.50  ? 213 ASN B OD1 1 
ATOM   4639 N ND2 . ASN B 1 213 ? 169.668 181.368 145.244 1.00 62.50  ? 213 ASN B ND2 1 
ATOM   4640 N N   . VAL B 1 214 ? 173.048 185.089 143.272 1.00 61.99  ? 214 VAL B N   1 
ATOM   4641 C CA  . VAL B 1 214 ? 174.091 185.389 142.289 1.00 61.99  ? 214 VAL B CA  1 
ATOM   4642 C C   . VAL B 1 214 ? 175.196 186.271 142.860 1.00 61.99  ? 214 VAL B C   1 
ATOM   4643 O O   . VAL B 1 214 ? 176.378 185.934 142.679 1.00 61.99  ? 214 VAL B O   1 
ATOM   4644 C CB  . VAL B 1 214 ? 173.464 185.973 141.013 1.00 61.99  ? 214 VAL B CB  1 
ATOM   4645 C CG1 . VAL B 1 214 ? 174.509 186.084 139.918 1.00 61.99  ? 214 VAL B CG1 1 
ATOM   4646 C CG2 . VAL B 1 214 ? 172.304 185.112 140.559 1.00 61.99  ? 214 VAL B CG2 1 
ATOM   4647 N N   . PRO B 1 215 ? 174.907 187.406 143.533 1.00 62.11  ? 215 PRO B N   1 
ATOM   4648 C CA  . PRO B 1 215 ? 176.006 188.203 144.096 1.00 62.11  ? 215 PRO B CA  1 
ATOM   4649 C C   . PRO B 1 215 ? 176.778 187.461 145.172 1.00 62.11  ? 215 PRO B C   1 
ATOM   4650 O O   . PRO B 1 215 ? 177.997 187.286 145.060 1.00 62.11  ? 215 PRO B O   1 
ATOM   4651 C CB  . PRO B 1 215 ? 175.292 189.432 144.674 1.00 62.11  ? 215 PRO B CB  1 
ATOM   4652 C CG  . PRO B 1 215 ? 174.007 189.500 143.952 1.00 62.11  ? 215 PRO B CG  1 
ATOM   4653 C CD  . PRO B 1 215 ? 173.612 188.081 143.727 1.00 62.11  ? 215 PRO B CD  1 
ATOM   4654 N N   . ILE B 1 216 ? 176.061 186.989 146.197 1.00 61.29  ? 216 ILE B N   1 
ATOM   4655 C CA  . ILE B 1 216 ? 176.710 186.429 147.381 1.00 61.29  ? 216 ILE B CA  1 
ATOM   4656 C C   . ILE B 1 216 ? 177.657 185.306 146.989 1.00 61.29  ? 216 ILE B C   1 
ATOM   4657 O O   . ILE B 1 216 ? 178.833 185.300 147.372 1.00 61.29  ? 216 ILE B O   1 
ATOM   4658 C CB  . ILE B 1 216 ? 175.656 185.942 148.390 1.00 61.29  ? 216 ILE B CB  1 
ATOM   4659 C CG1 . ILE B 1 216 ? 174.678 187.067 148.729 1.00 61.29  ? 216 ILE B CG1 1 
ATOM   4660 C CG2 . ILE B 1 216 ? 176.327 185.415 149.645 1.00 61.29  ? 216 ILE B CG2 1 
ATOM   4661 C CD1 . ILE B 1 216 ? 173.539 186.629 149.611 1.00 61.29  ? 216 ILE B CD1 1 
ATOM   4662 N N   . GLY B 1 217 ? 177.171 184.365 146.178 1.00 59.79  ? 217 GLY B N   1 
ATOM   4663 C CA  . GLY B 1 217 ? 178.018 183.263 145.756 1.00 59.79  ? 217 GLY B CA  1 
ATOM   4664 C C   . GLY B 1 217 ? 179.288 183.746 145.089 1.00 59.79  ? 217 GLY B C   1 
ATOM   4665 O O   . GLY B 1 217 ? 180.387 183.292 145.418 1.00 59.79  ? 217 GLY B O   1 
ATOM   4666 N N   . LEU B 1 218 ? 179.157 184.719 144.182 1.00 59.51  ? 218 LEU B N   1 
ATOM   4667 C CA  . LEU B 1 218 ? 180.331 185.282 143.527 1.00 59.51  ? 218 LEU B CA  1 
ATOM   4668 C C   . LEU B 1 218 ? 181.343 185.754 144.558 1.00 59.51  ? 218 LEU B C   1 
ATOM   4669 O O   . LEU B 1 218 ? 182.531 185.418 144.480 1.00 59.51  ? 218 LEU B O   1 
ATOM   4670 C CB  . LEU B 1 218 ? 179.923 186.433 142.607 1.00 59.51  ? 218 LEU B CB  1 
ATOM   4671 C CG  . LEU B 1 218 ? 179.361 186.061 141.234 1.00 59.51  ? 218 LEU B CG  1 
ATOM   4672 C CD1 . LEU B 1 218 ? 178.673 187.256 140.602 1.00 59.51  ? 218 LEU B CD1 1 
ATOM   4673 C CD2 . LEU B 1 218 ? 180.463 185.540 140.332 1.00 59.51  ? 218 LEU B CD2 1 
ATOM   4674 N N   . VAL B 1 219 ? 180.869 186.480 145.576 1.00 60.78  ? 219 VAL B N   1 
ATOM   4675 C CA  . VAL B 1 219 ? 181.766 186.973 146.617 1.00 60.78  ? 219 VAL B CA  1 
ATOM   4676 C C   . VAL B 1 219 ? 182.538 185.812 147.221 1.00 60.78  ? 219 VAL B C   1 
ATOM   4677 O O   . VAL B 1 219 ? 183.774 185.837 147.300 1.00 60.78  ? 219 VAL B O   1 
ATOM   4678 C CB  . VAL B 1 219 ? 180.975 187.742 147.689 1.00 60.78  ? 219 VAL B CB  1 
ATOM   4679 C CG1 . VAL B 1 219 ? 181.858 188.040 148.885 1.00 60.78  ? 219 VAL B CG1 1 
ATOM   4680 C CG2 . VAL B 1 219 ? 180.401 189.021 147.108 1.00 60.78  ? 219 VAL B CG2 1 
ATOM   4681 N N   . MET B 1 220 ? 181.821 184.743 147.582 1.00 60.50  ? 220 MET B N   1 
ATOM   4682 C CA  . MET B 1 220 ? 182.479 183.591 148.185 1.00 60.50  ? 220 MET B CA  1 
ATOM   4683 C C   . MET B 1 220 ? 183.590 183.074 147.286 1.00 60.50  ? 220 MET B C   1 
ATOM   4684 O O   . MET B 1 220 ? 184.714 182.844 147.751 1.00 60.50  ? 220 MET B O   1 
ATOM   4685 C CB  . MET B 1 220 ? 181.459 182.490 148.474 1.00 60.50  ? 220 MET B CB  1 
ATOM   4686 C CG  . MET B 1 220 ? 180.405 182.883 149.491 1.00 60.50  ? 220 MET B CG  1 
ATOM   4687 S SD  . MET B 1 220 ? 181.079 183.887 150.827 1.00 60.50  ? 220 MET B SD  1 
ATOM   4688 C CE  . MET B 1 220 ? 179.646 184.061 151.882 1.00 60.50  ? 220 MET B CE  1 
ATOM   4689 N N   . ILE B 1 221 ? 183.316 182.961 145.983 1.00 58.60  ? 221 ILE B N   1 
ATOM   4690 C CA  . ILE B 1 221 ? 184.326 182.451 145.063 1.00 58.60  ? 221 ILE B CA  1 
ATOM   4691 C C   . ILE B 1 221 ? 185.592 183.284 145.174 1.00 58.60  ? 221 ILE B C   1 
ATOM   4692 O O   . ILE B 1 221 ? 186.695 182.748 145.347 1.00 58.60  ? 221 ILE B O   1 
ATOM   4693 C CB  . ILE B 1 221 ? 183.789 182.431 143.622 1.00 58.60  ? 221 ILE B CB  1 
ATOM   4694 C CG1 . ILE B 1 221 ? 182.751 181.326 143.452 1.00 58.60  ? 221 ILE B CG1 1 
ATOM   4695 C CG2 . ILE B 1 221 ? 184.923 182.223 142.639 1.00 58.60  ? 221 ILE B CG2 1 
ATOM   4696 C CD1 . ILE B 1 221 ? 181.884 181.498 142.230 1.00 58.60  ? 221 ILE B CD1 1 
ATOM   4697 N N   . TYR B 1 222 ? 185.441 184.611 145.151 1.00 65.26  ? 222 TYR B N   1 
ATOM   4698 C CA  . TYR B 1 222 ? 186.607 185.478 145.264 1.00 65.26  ? 222 TYR B CA  1 
ATOM   4699 C C   . TYR B 1 222 ? 187.390 185.155 146.526 1.00 65.26  ? 222 TYR B C   1 
ATOM   4700 O O   . TYR B 1 222 ? 188.601 184.908 146.474 1.00 65.26  ? 222 TYR B O   1 
ATOM   4701 C CB  . TYR B 1 222 ? 186.179 186.945 145.252 1.00 65.26  ? 222 TYR B CB  1 
ATOM   4702 C CG  . TYR B 1 222 ? 187.335 187.910 145.373 1.00 65.26  ? 222 TYR B CG  1 
ATOM   4703 C CD1 . TYR B 1 222 ? 188.328 187.955 144.405 1.00 65.26  ? 222 TYR B CD1 1 
ATOM   4704 C CD2 . TYR B 1 222 ? 187.435 188.773 146.455 1.00 65.26  ? 222 TYR B CD2 1 
ATOM   4705 C CE1 . TYR B 1 222 ? 189.388 188.831 144.511 1.00 65.26  ? 222 TYR B CE1 1 
ATOM   4706 C CE2 . TYR B 1 222 ? 188.492 189.653 146.569 1.00 65.26  ? 222 TYR B CE2 1 
ATOM   4707 C CZ  . TYR B 1 222 ? 189.465 189.678 145.594 1.00 65.26  ? 222 TYR B CZ  1 
ATOM   4708 O OH  . TYR B 1 222 ? 190.520 190.552 145.701 1.00 65.26  ? 222 TYR B OH  1 
ATOM   4709 N N   . LEU B 1 223 ? 186.694 185.076 147.662 1.00 62.58  ? 223 LEU B N   1 
ATOM   4710 C CA  . LEU B 1 223 ? 187.379 184.769 148.909 1.00 62.58  ? 223 LEU B CA  1 
ATOM   4711 C C   . LEU B 1 223 ? 188.030 183.396 148.838 1.00 62.58  ? 223 LEU B C   1 
ATOM   4712 O O   . LEU B 1 223 ? 189.173 183.218 149.276 1.00 62.58  ? 223 LEU B O   1 
ATOM   4713 C CB  . LEU B 1 223 ? 186.401 184.855 150.078 1.00 62.58  ? 223 LEU B CB  1 
ATOM   4714 C CG  . LEU B 1 223 ? 186.011 186.274 150.496 1.00 62.58  ? 223 LEU B CG  1 
ATOM   4715 C CD1 . LEU B 1 223 ? 184.957 186.246 151.588 1.00 62.58  ? 223 LEU B CD1 1 
ATOM   4716 C CD2 . LEU B 1 223 ? 187.233 187.051 150.948 1.00 62.58  ? 223 LEU B CD2 1 
ATOM   4717 N N   . ALA B 1 224 ? 187.335 182.422 148.240 1.00 63.47  ? 224 ALA B N   1 
ATOM   4718 C CA  . ALA B 1 224 ? 187.898 181.083 148.139 1.00 63.47  ? 224 ALA B CA  1 
ATOM   4719 C C   . ALA B 1 224 ? 189.167 181.077 147.300 1.00 63.47  ? 224 ALA B C   1 
ATOM   4720 O O   . ALA B 1 224 ? 190.033 180.217 147.491 1.00 63.47  ? 224 ALA B O   1 
ATOM   4721 C CB  . ALA B 1 224 ? 186.867 180.119 147.555 1.00 63.47  ? 224 ALA B CB  1 
ATOM   4722 N N   . ARG B 1 225 ? 189.302 182.028 146.376 1.00 67.90  ? 225 ARG B N   1 
ATOM   4723 C CA  . ARG B 1 225 ? 190.499 182.092 145.553 1.00 67.90  ? 225 ARG B CA  1 
ATOM   4724 C C   . ARG B 1 225 ? 191.617 182.895 146.199 1.00 67.90  ? 225 ARG B C   1 
ATOM   4725 O O   . ARG B 1 225 ? 192.734 182.900 145.675 1.00 67.90  ? 225 ARG B O   1 
ATOM   4726 C CB  . ARG B 1 225 ? 190.166 182.693 144.187 1.00 67.90  ? 225 ARG B CB  1 
ATOM   4727 C CG  . ARG B 1 225 ? 189.914 181.668 143.100 1.00 67.90  ? 225 ARG B CG  1 
ATOM   4728 C CD  . ARG B 1 225 ? 189.782 182.335 141.743 1.00 67.90  ? 225 ARG B CD  1 
ATOM   4729 N NE  . ARG B 1 225 ? 191.021 182.983 141.330 1.00 67.90  ? 225 ARG B NE  1 
ATOM   4730 C CZ  . ARG B 1 225 ? 191.213 184.295 141.317 1.00 67.90  ? 225 ARG B CZ  1 
ATOM   4731 N NH1 . ARG B 1 225 ? 190.265 185.136 141.696 1.00 67.90  ? 225 ARG B NH1 1 
ATOM   4732 N NH2 . ARG B 1 225 ? 192.386 184.775 140.916 1.00 67.90  ? 225 ARG B NH2 1 
ATOM   4733 N N   . THR B 1 226 ? 191.349 183.564 147.320 1.00 69.31  ? 226 THR B N   1 
ATOM   4734 C CA  . THR B 1 226 ? 192.315 184.478 147.920 1.00 69.31  ? 226 THR B CA  1 
ATOM   4735 C C   . THR B 1 226 ? 192.844 183.961 149.253 1.00 69.31  ? 226 THR B C   1 
ATOM   4736 O O   . THR B 1 226 ? 194.058 183.846 149.441 1.00 69.31  ? 226 THR B O   1 
ATOM   4737 C CB  . THR B 1 226 ? 191.673 185.860 148.096 1.00 69.31  ? 226 THR B CB  1 
ATOM   4738 O OG1 . THR B 1 226 ? 191.521 186.482 146.815 1.00 69.31  ? 226 THR B OG1 1 
ATOM   4739 C CG2 . THR B 1 226 ? 192.532 186.743 148.980 1.00 69.31  ? 226 THR B CG2 1 
ATOM   4740 N N   . ALA B 1 227 ? 191.946 183.642 150.186 1.00 69.86  ? 227 ALA B N   1 
ATOM   4741 C CA  . ALA B 1 227 ? 192.378 183.270 151.528 1.00 69.86  ? 227 ALA B CA  1 
ATOM   4742 C C   . ALA B 1 227 ? 192.973 181.868 151.563 1.00 69.86  ? 227 ALA B C   1 
ATOM   4743 O O   . ALA B 1 227 ? 193.996 181.641 152.218 1.00 69.86  ? 227 ALA B O   1 
ATOM   4744 C CB  . ALA B 1 227 ? 191.205 183.377 152.498 1.00 69.86  ? 227 ALA B CB  1 
ATOM   4745 N N   . LEU B 1 228 ? 192.349 180.917 150.875 1.00 70.78  ? 228 LEU B N   1 
ATOM   4746 C CA  . LEU B 1 228 ? 192.774 179.530 150.966 1.00 70.78  ? 228 LEU B CA  1 
ATOM   4747 C C   . LEU B 1 228 ? 194.051 179.291 150.165 1.00 70.78  ? 228 LEU B C   1 
ATOM   4748 O O   . LEU B 1 228 ? 194.379 180.020 149.226 1.00 70.78  ? 228 LEU B O   1 
ATOM   4749 C CB  . LEU B 1 228 ? 191.668 178.597 150.477 1.00 70.78  ? 228 LEU B CB  1 
ATOM   4750 C CG  . LEU B 1 228 ? 190.360 178.650 151.267 1.00 70.78  ? 228 LEU B CG  1 
ATOM   4751 C CD1 . LEU B 1 228 ? 189.339 177.683 150.691 1.00 70.78  ? 228 LEU B CD1 1 
ATOM   4752 C CD2 . LEU B 1 228 ? 190.614 178.355 152.733 1.00 70.78  ? 228 LEU B CD2 1 
ATOM   4753 N N   . ARG B 1 229 ? 194.775 178.245 150.557 1.00 79.37  ? 229 ARG B N   1 
ATOM   4754 C CA  . ARG B 1 229 ? 195.989 177.813 149.883 1.00 79.37  ? 229 ARG B CA  1 
ATOM   4755 C C   . ARG B 1 229 ? 195.867 176.341 149.523 1.00 79.37  ? 229 ARG B C   1 
ATOM   4756 O O   . ARG B 1 229 ? 195.102 175.592 150.136 1.00 79.37  ? 229 ARG B O   1 
ATOM   4757 C CB  . ARG B 1 229 ? 197.240 178.031 150.749 1.00 79.37  ? 229 ARG B CB  1 
ATOM   4758 C CG  . ARG B 1 229 ? 197.727 179.469 150.834 1.00 79.37  ? 229 ARG B CG  1 
ATOM   4759 C CD  . ARG B 1 229 ? 196.999 180.255 151.908 1.00 79.37  ? 229 ARG B CD  1 
ATOM   4760 N NE  . ARG B 1 229 ? 197.621 181.552 152.144 1.00 79.37  ? 229 ARG B NE  1 
ATOM   4761 C CZ  . ARG B 1 229 ? 197.256 182.678 151.548 1.00 79.37  ? 229 ARG B CZ  1 
ATOM   4762 N NH1 . ARG B 1 229 ? 196.290 182.701 150.646 1.00 79.37  ? 229 ARG B NH1 1 
ATOM   4763 N NH2 . ARG B 1 229 ? 197.882 183.809 151.860 1.00 79.37  ? 229 ARG B NH2 1 
ATOM   4764 N N   . GLU B 1 230 ? 196.634 175.930 148.519 1.00 91.33  ? 230 GLU B N   1 
ATOM   4765 C CA  . GLU B 1 230 ? 196.628 174.556 148.034 1.00 91.33  ? 230 GLU B CA  1 
ATOM   4766 C C   . GLU B 1 230 ? 197.912 173.869 148.482 1.00 91.33  ? 230 GLU B C   1 
ATOM   4767 O O   . GLU B 1 230 ? 199.011 174.354 148.195 1.00 91.33  ? 230 GLU B O   1 
ATOM   4768 C CB  . GLU B 1 230 ? 196.494 174.514 146.513 1.00 91.33  ? 230 GLU B CB  1 
ATOM   4769 C CG  . GLU B 1 230 ? 196.397 173.110 145.939 1.00 91.33  ? 230 GLU B CG  1 
ATOM   4770 C CD  . GLU B 1 230 ? 195.092 172.425 146.297 1.00 91.33  ? 230 GLU B CD  1 
ATOM   4771 O OE1 . GLU B 1 230 ? 195.035 171.761 147.353 1.00 91.33  ? 230 GLU B OE1 1 
ATOM   4772 O OE2 . GLU B 1 230 ? 194.121 172.553 145.521 1.00 91.33  ? 230 GLU B OE2 1 
ATOM   4773 N N   . THR B 1 231 ? 197.768 172.743 149.180 1.00 99.22  ? 231 THR B N   1 
ATOM   4774 C CA  . THR B 1 231 ? 198.915 172.008 149.699 1.00 99.22  ? 231 THR B CA  1 
ATOM   4775 C C   . THR B 1 231 ? 199.579 171.121 148.654 1.00 99.22  ? 231 THR B C   1 
ATOM   4776 O O   . THR B 1 231 ? 200.690 170.637 148.899 1.00 99.22  ? 231 THR B O   1 
ATOM   4777 C CB  . THR B 1 231 ? 198.496 171.152 150.896 1.00 99.22  ? 231 THR B CB  1 
ATOM   4778 O OG1 . THR B 1 231 ? 197.579 170.140 150.463 1.00 99.22  ? 231 THR B OG1 1 
ATOM   4779 C CG2 . THR B 1 231 ? 197.828 172.014 151.955 1.00 99.22  ? 231 THR B CG2 1 
ATOM   4780 N N   . ASN B 1 232 ? 198.929 170.899 147.510 1.00 100.96 ? 232 ASN B N   1 
ATOM   4781 C CA  . ASN B 1 232 ? 199.478 170.083 146.425 1.00 100.96 ? 232 ASN B CA  1 
ATOM   4782 C C   . ASN B 1 232 ? 199.841 168.680 146.906 1.00 100.96 ? 232 ASN B C   1 
ATOM   4783 O O   . ASN B 1 232 ? 200.893 168.136 146.562 1.00 100.96 ? 232 ASN B O   1 
ATOM   4784 C CB  . ASN B 1 232 ? 200.684 170.767 145.776 1.00 100.96 ? 232 ASN B CB  1 
ATOM   4785 C CG  . ASN B 1 232 ? 200.300 172.022 145.017 1.00 100.96 ? 232 ASN B CG  1 
ATOM   4786 O OD1 . ASN B 1 232 ? 199.823 171.954 143.884 1.00 100.96 ? 232 ASN B OD1 1 
ATOM   4787 N ND2 . ASN B 1 232 ? 200.505 173.177 145.640 1.00 100.96 ? 232 ASN B ND2 1 
ATOM   4788 N N   . LYS B 1 233 ? 198.963 168.089 147.711 1.00 98.72  ? 233 LYS B N   1 
ATOM   4789 C CA  . LYS B 1 233 ? 199.164 166.728 148.178 1.00 98.72  ? 233 LYS B CA  1 
ATOM   4790 C C   . LYS B 1 233 ? 198.983 165.740 147.028 1.00 98.72  ? 233 LYS B C   1 
ATOM   4791 O O   . LYS B 1 233 ? 198.339 166.034 146.017 1.00 98.72  ? 233 LYS B O   1 
ATOM   4792 C CB  . LYS B 1 233 ? 198.193 166.407 149.316 1.00 98.72  ? 233 LYS B CB  1 
ATOM   4793 C CG  . LYS B 1 233 ? 198.573 165.196 150.153 1.00 98.72  ? 233 LYS B CG  1 
ATOM   4794 C CD  . LYS B 1 233 ? 199.884 165.415 150.884 1.00 98.72  ? 233 LYS B CD  1 
ATOM   4795 C CE  . LYS B 1 233 ? 200.243 164.211 151.739 1.00 98.72  ? 233 LYS B CE  1 
ATOM   4796 N NZ  . LYS B 1 233 ? 200.515 163.004 150.910 1.00 98.72  ? 233 LYS B NZ  1 
ATOM   4797 N N   . GLU B 1 234 ? 199.577 164.559 147.186 1.00 96.54  ? 234 GLU B N   1 
ATOM   4798 C CA  . GLU B 1 234 ? 199.475 163.531 146.159 1.00 96.54  ? 234 GLU B CA  1 
ATOM   4799 C C   . GLU B 1 234 ? 198.027 163.095 145.976 1.00 96.54  ? 234 GLU B C   1 
ATOM   4800 O O   . GLU B 1 234 ? 197.289 162.898 146.944 1.00 96.54  ? 234 GLU B O   1 
ATOM   4801 C CB  . GLU B 1 234 ? 200.348 162.330 146.520 1.00 96.54  ? 234 GLU B CB  1 
ATOM   4802 C CG  . GLU B 1 234 ? 201.829 162.560 146.282 1.00 96.54  ? 234 GLU B CG  1 
ATOM   4803 C CD  . GLU B 1 234 ? 202.152 162.792 144.818 1.00 96.54  ? 234 GLU B CD  1 
ATOM   4804 O OE1 . GLU B 1 234 ? 201.461 162.212 143.954 1.00 96.54  ? 234 GLU B OE1 1 
ATOM   4805 O OE2 . GLU B 1 234 ? 203.096 163.558 144.531 1.00 96.54  ? 234 GLU B OE2 1 
ATOM   4806 N N   . ARG B 1 235 ? 197.625 162.946 144.717 1.00 86.86  ? 235 ARG B N   1 
ATOM   4807 C CA  . ARG B 1 235 ? 196.238 162.661 144.388 1.00 86.86  ? 235 ARG B CA  1 
ATOM   4808 C C   . ARG B 1 235 ? 195.963 161.165 144.470 1.00 86.86  ? 235 ARG B C   1 
ATOM   4809 O O   . ARG B 1 235 ? 196.767 160.345 144.021 1.00 86.86  ? 235 ARG B O   1 
ATOM   4810 C CB  . ARG B 1 235 ? 195.920 163.179 142.986 1.00 86.86  ? 235 ARG B CB  1 
ATOM   4811 C CG  . ARG B 1 235 ? 196.040 164.687 142.861 1.00 86.86  ? 235 ARG B CG  1 
ATOM   4812 C CD  . ARG B 1 235 ? 194.955 165.404 143.635 1.00 86.86  ? 235 ARG B CD  1 
ATOM   4813 N NE  . ARG B 1 235 ? 195.007 166.845 143.425 1.00 86.86  ? 235 ARG B NE  1 
ATOM   4814 C CZ  . ARG B 1 235 ? 195.694 167.684 144.186 1.00 86.86  ? 235 ARG B CZ  1 
ATOM   4815 N NH1 . ARG B 1 235 ? 196.383 167.261 145.233 1.00 86.86  ? 235 ARG B NH1 1 
ATOM   4816 N NH2 . ARG B 1 235 ? 195.687 168.981 143.893 1.00 86.86  ? 235 ARG B NH2 1 
ATOM   4817 N N   . MET B 1 236 ? 194.816 160.813 145.046 1.00 83.36  ? 236 MET B N   1 
ATOM   4818 C CA  . MET B 1 236 ? 194.425 159.422 145.189 1.00 83.36  ? 236 MET B CA  1 
ATOM   4819 C C   . MET B 1 236 ? 193.697 158.942 143.935 1.00 83.36  ? 236 MET B C   1 
ATOM   4820 O O   . MET B 1 236 ? 193.513 159.683 142.966 1.00 83.36  ? 236 MET B O   1 
ATOM   4821 C CB  . MET B 1 236 ? 193.552 159.236 146.428 1.00 83.36  ? 236 MET B CB  1 
ATOM   4822 C CG  . MET B 1 236 ? 194.099 159.884 147.685 1.00 83.36  ? 236 MET B CG  1 
ATOM   4823 S SD  . MET B 1 236 ? 193.226 159.328 149.161 1.00 83.36  ? 236 MET B SD  1 
ATOM   4824 C CE  . MET B 1 236 ? 194.336 159.890 150.447 1.00 83.36  ? 236 MET B CE  1 
ATOM   4825 N N   . LYS B 1 237 ? 193.275 157.681 143.953 1.00 83.77  ? 237 LYS B N   1 
ATOM   4826 C CA  . LYS B 1 237 ? 192.537 157.074 142.855 1.00 83.77  ? 237 LYS B CA  1 
ATOM   4827 C C   . LYS B 1 237 ? 191.090 156.867 143.276 1.00 83.77  ? 237 LYS B C   1 
ATOM   4828 O O   . LYS B 1 237 ? 190.823 156.291 144.335 1.00 83.77  ? 237 LYS B O   1 
ATOM   4829 C CB  . LYS B 1 237 ? 193.163 155.742 142.439 1.00 83.77  ? 237 LYS B CB  1 
ATOM   4830 C CG  . LYS B 1 237 ? 194.578 155.861 141.908 1.00 83.77  ? 237 LYS B CG  1 
ATOM   4831 C CD  . LYS B 1 237 ? 194.613 156.671 140.624 1.00 83.77  ? 237 LYS B CD  1 
ATOM   4832 C CE  . LYS B 1 237 ? 193.990 155.905 139.471 1.00 83.77  ? 237 LYS B CE  1 
ATOM   4833 N NZ  . LYS B 1 237 ? 194.085 156.654 138.188 1.00 83.77  ? 237 LYS B NZ  1 
ATOM   4834 N N   . LEU B 1 238 ? 190.164 157.332 142.444 1.00 79.86  ? 238 LEU B N   1 
ATOM   4835 C CA  . LEU B 1 238 ? 188.750 157.262 142.778 1.00 79.86  ? 238 LEU B CA  1 
ATOM   4836 C C   . LEU B 1 238 ? 188.261 155.818 142.779 1.00 79.86  ? 238 LEU B C   1 
ATOM   4837 O O   . LEU B 1 238 ? 188.741 154.971 142.022 1.00 79.86  ? 238 LEU B O   1 
ATOM   4838 C CB  . LEU B 1 238 ? 187.929 158.090 141.790 1.00 79.86  ? 238 LEU B CB  1 
ATOM   4839 C CG  . LEU B 1 238 ? 186.497 158.434 142.202 1.00 79.86  ? 238 LEU B CG  1 
ATOM   4840 C CD1 . LEU B 1 238 ? 186.489 159.529 143.251 1.00 79.86  ? 238 LEU B CD1 1 
ATOM   4841 C CD2 . LEU B 1 238 ? 185.675 158.839 140.993 1.00 79.86  ? 238 LEU B CD2 1 
ATOM   4842 N N   . ASP B 1 239 ? 187.296 155.544 143.654 1.00 81.58  ? 239 ASP B N   1 
ATOM   4843 C CA  . ASP B 1 239 ? 186.620 154.251 143.725 1.00 81.58  ? 239 ASP B CA  1 
ATOM   4844 C C   . ASP B 1 239 ? 185.341 154.360 142.903 1.00 81.58  ? 239 ASP B C   1 
ATOM   4845 O O   . ASP B 1 239 ? 184.317 154.842 143.392 1.00 81.58  ? 239 ASP B O   1 
ATOM   4846 C CB  . ASP B 1 239 ? 186.334 153.875 145.174 1.00 81.58  ? 239 ASP B CB  1 
ATOM   4847 C CG  . ASP B 1 239 ? 185.921 152.431 145.330 1.00 81.58  ? 239 ASP B CG  1 
ATOM   4848 O OD1 . ASP B 1 239 ? 186.558 151.561 144.702 1.00 81.58  ? 239 ASP B OD1 1 
ATOM   4849 O OD2 . ASP B 1 239 ? 184.962 152.165 146.084 1.00 81.58  ? 239 ASP B OD2 1 
ATOM   4850 N N   . ALA B 1 240 ? 185.402 153.915 141.647 1.00 78.81  ? 240 ALA B N   1 
ATOM   4851 C CA  . ALA B 1 240 ? 184.288 154.134 140.728 1.00 78.81  ? 240 ALA B CA  1 
ATOM   4852 C C   . ALA B 1 240 ? 183.075 153.289 141.100 1.00 78.81  ? 240 ALA B C   1 
ATOM   4853 O O   . ALA B 1 240 ? 181.950 153.798 141.165 1.00 78.81  ? 240 ALA B O   1 
ATOM   4854 C CB  . ALA B 1 240 ? 184.728 153.840 139.295 1.00 78.81  ? 240 ALA B CB  1 
ATOM   4855 N N   . THR B 1 241 ? 183.283 151.993 141.343 1.00 77.76  ? 241 THR B N   1 
ATOM   4856 C CA  . THR B 1 241 ? 182.159 151.100 141.611 1.00 77.76  ? 241 THR B CA  1 
ATOM   4857 C C   . THR B 1 241 ? 181.446 151.476 142.903 1.00 77.76  ? 241 THR B C   1 
ATOM   4858 O O   . THR B 1 241 ? 180.209 151.515 142.951 1.00 77.76  ? 241 THR B O   1 
ATOM   4859 C CB  . THR B 1 241 ? 182.644 149.652 141.672 1.00 77.76  ? 241 THR B CB  1 
ATOM   4860 O OG1 . THR B 1 241 ? 183.423 149.361 140.505 1.00 77.76  ? 241 THR B OG1 1 
ATOM   4861 C CG2 . THR B 1 241 ? 181.464 148.698 141.735 1.00 77.76  ? 241 THR B CG2 1 
ATOM   4862 N N   . GLY B 1 242 ? 182.209 151.758 143.959 1.00 76.33  ? 242 GLY B N   1 
ATOM   4863 C CA  . GLY B 1 242 ? 181.597 152.153 145.214 1.00 76.33  ? 242 GLY B CA  1 
ATOM   4864 C C   . GLY B 1 242 ? 180.820 153.448 145.099 1.00 76.33  ? 242 GLY B C   1 
ATOM   4865 O O   . GLY B 1 242 ? 179.715 153.569 145.632 1.00 76.33  ? 242 GLY B O   1 
ATOM   4866 N N   . ALA B 1 243 ? 181.384 154.433 144.396 1.00 74.23  ? 243 ALA B N   1 
ATOM   4867 C CA  . ALA B 1 243 ? 180.688 155.702 144.210 1.00 74.23  ? 243 ALA B CA  1 
ATOM   4868 C C   . ALA B 1 243 ? 179.397 155.516 143.423 1.00 74.23  ? 243 ALA B C   1 
ATOM   4869 O O   . ALA B 1 243 ? 178.357 156.084 143.779 1.00 74.23  ? 243 ALA B O   1 
ATOM   4870 C CB  . ALA B 1 243 ? 181.605 156.703 143.509 1.00 74.23  ? 243 ALA B CB  1 
ATOM   4871 N N   . ILE B 1 244 ? 179.443 154.718 142.354 1.00 74.16  ? 244 ILE B N   1 
ATOM   4872 C CA  . ILE B 1 244 ? 178.249 154.487 141.544 1.00 74.16  ? 244 ILE B CA  1 
ATOM   4873 C C   . ILE B 1 244 ? 177.170 153.801 142.372 1.00 74.16  ? 244 ILE B C   1 
ATOM   4874 O O   . ILE B 1 244 ? 175.997 154.194 142.348 1.00 74.16  ? 244 ILE B O   1 
ATOM   4875 C CB  . ILE B 1 244 ? 178.603 153.669 140.290 1.00 74.16  ? 244 ILE B CB  1 
ATOM   4876 C CG1 . ILE B 1 244 ? 179.231 154.569 139.226 1.00 74.16  ? 244 ILE B CG1 1 
ATOM   4877 C CG2 . ILE B 1 244 ? 177.371 152.974 139.737 1.00 74.16  ? 244 ILE B CG2 1 
ATOM   4878 C CD1 . ILE B 1 244 ? 179.729 153.821 138.017 1.00 74.16  ? 244 ILE B CD1 1 
ATOM   4879 N N   . LEU B 1 245 ? 177.553 152.768 143.127 1.00 74.50  ? 245 LEU B N   1 
ATOM   4880 C CA  . LEU B 1 245 ? 176.574 152.050 143.935 1.00 74.50  ? 245 LEU B CA  1 
ATOM   4881 C C   . LEU B 1 245 ? 175.985 152.944 145.020 1.00 74.50  ? 245 LEU B C   1 
ATOM   4882 O O   . LEU B 1 245 ? 174.775 152.908 145.275 1.00 74.50  ? 245 LEU B O   1 
ATOM   4883 C CB  . LEU B 1 245 ? 177.214 150.804 144.546 1.00 74.50  ? 245 LEU B CB  1 
ATOM   4884 C CG  . LEU B 1 245 ? 177.474 149.650 143.575 1.00 74.50  ? 245 LEU B CG  1 
ATOM   4885 C CD1 . LEU B 1 245 ? 178.306 148.567 144.233 1.00 74.50  ? 245 LEU B CD1 1 
ATOM   4886 C CD2 . LEU B 1 245 ? 176.166 149.080 143.051 1.00 74.50  ? 245 LEU B CD2 1 
ATOM   4887 N N   . ALA B 1 246 ? 176.824 153.761 145.665 1.00 73.48  ? 246 ALA B N   1 
ATOM   4888 C CA  . ALA B 1 246 ? 176.332 154.651 146.710 1.00 73.48  ? 246 ALA B CA  1 
ATOM   4889 C C   . ALA B 1 246 ? 175.363 155.681 146.150 1.00 73.48  ? 246 ALA B C   1 
ATOM   4890 O O   . ALA B 1 246 ? 174.309 155.937 146.745 1.00 73.48  ? 246 ALA B O   1 
ATOM   4891 C CB  . ALA B 1 246 ? 177.503 155.342 147.406 1.00 73.48  ? 246 ALA B CB  1 
ATOM   4892 N N   . THR B 1 247 ? 175.700 156.286 145.008 1.00 71.45  ? 247 THR B N   1 
ATOM   4893 C CA  . THR B 1 247 ? 174.803 157.272 144.416 1.00 71.45  ? 247 THR B CA  1 
ATOM   4894 C C   . THR B 1 247 ? 173.489 156.634 143.991 1.00 71.45  ? 247 THR B C   1 
ATOM   4895 O O   . THR B 1 247 ? 172.417 157.215 144.198 1.00 71.45  ? 247 THR B O   1 
ATOM   4896 C CB  . THR B 1 247 ? 175.472 157.962 143.230 1.00 71.45  ? 247 THR B CB  1 
ATOM   4897 O OG1 . THR B 1 247 ? 175.890 156.980 142.277 1.00 71.45  ? 247 THR B OG1 1 
ATOM   4898 C CG2 . THR B 1 247 ? 176.677 158.758 143.693 1.00 71.45  ? 247 THR B CG2 1 
ATOM   4899 N N   . LEU B 1 248 ? 173.546 155.436 143.403 1.00 72.34  ? 248 LEU B N   1 
ATOM   4900 C CA  . LEU B 1 248 ? 172.317 154.755 143.009 1.00 72.34  ? 248 LEU B CA  1 
ATOM   4901 C C   . LEU B 1 248 ? 171.436 154.465 144.218 1.00 72.34  ? 248 LEU B C   1 
ATOM   4902 O O   . LEU B 1 248 ? 170.228 154.728 144.196 1.00 72.34  ? 248 LEU B O   1 
ATOM   4903 C CB  . LEU B 1 248 ? 172.648 153.463 142.265 1.00 72.34  ? 248 LEU B CB  1 
ATOM   4904 C CG  . LEU B 1 248 ? 171.448 152.632 141.811 1.00 72.34  ? 248 LEU B CG  1 
ATOM   4905 C CD1 . LEU B 1 248 ? 170.642 153.382 140.767 1.00 72.34  ? 248 LEU B CD1 1 
ATOM   4906 C CD2 . LEU B 1 248 ? 171.901 151.286 141.277 1.00 72.34  ? 248 LEU B CD2 1 
ATOM   4907 N N   . ALA B 1 249 ? 172.029 153.936 145.290 1.00 74.50  ? 249 ALA B N   1 
ATOM   4908 C CA  . ALA B 1 249 ? 171.252 153.612 146.482 1.00 74.50  ? 249 ALA B CA  1 
ATOM   4909 C C   . ALA B 1 249 ? 170.635 154.861 147.097 1.00 74.50  ? 249 ALA B C   1 
ATOM   4910 O O   . ALA B 1 249 ? 169.452 154.869 147.461 1.00 74.50  ? 249 ALA B O   1 
ATOM   4911 C CB  . ALA B 1 249 ? 172.133 152.893 147.501 1.00 74.50  ? 249 ALA B CB  1 
ATOM   4912 N N   . CYS B 1 250 ? 171.423 155.932 147.220 1.00 72.67  ? 250 CYS B N   1 
ATOM   4913 C CA  . CYS B 1 250 ? 170.914 157.150 147.840 1.00 72.67  ? 250 CYS B CA  1 
ATOM   4914 C C   . CYS B 1 250 ? 169.807 157.780 147.004 1.00 72.67  ? 250 CYS B C   1 
ATOM   4915 O O   . CYS B 1 250 ? 168.776 158.201 147.547 1.00 72.67  ? 250 CYS B O   1 
ATOM   4916 C CB  . CYS B 1 250 ? 172.057 158.138 148.061 1.00 72.67  ? 250 CYS B CB  1 
ATOM   4917 S SG  . CYS B 1 250 ? 173.256 157.611 149.306 1.00 72.67  ? 250 CYS B SG  1 
ATOM   4918 N N   . THR B 1 251 ? 169.993 157.846 145.683 1.00 72.28  ? 251 THR B N   1 
ATOM   4919 C CA  . THR B 1 251 ? 168.962 158.410 144.820 1.00 72.28  ? 251 THR B CA  1 
ATOM   4920 C C   . THR B 1 251 ? 167.685 157.584 144.874 1.00 72.28  ? 251 THR B C   1 
ATOM   4921 O O   . THR B 1 251 ? 166.583 158.139 144.947 1.00 72.28  ? 251 THR B O   1 
ATOM   4922 C CB  . THR B 1 251 ? 169.476 158.510 143.386 1.00 72.28  ? 251 THR B CB  1 
ATOM   4923 O OG1 . THR B 1 251 ? 170.632 159.354 143.351 1.00 72.28  ? 251 THR B OG1 1 
ATOM   4924 C CG2 . THR B 1 251 ? 168.411 159.093 142.479 1.00 72.28  ? 251 THR B CG2 1 
ATOM   4925 N N   . ALA B 1 252 ? 167.811 156.254 144.846 1.00 77.80  ? 252 ALA B N   1 
ATOM   4926 C CA  . ALA B 1 252 ? 166.628 155.404 144.916 1.00 77.80  ? 252 ALA B CA  1 
ATOM   4927 C C   . ALA B 1 252 ? 165.891 155.593 146.234 1.00 77.80  ? 252 ALA B C   1 
ATOM   4928 O O   . ALA B 1 252 ? 164.658 155.691 146.254 1.00 77.80  ? 252 ALA B O   1 
ATOM   4929 C CB  . ALA B 1 252 ? 167.024 153.942 144.726 1.00 77.80  ? 252 ALA B CB  1 
ATOM   4930 N N   . ALA B 1 253 ? 166.627 155.654 147.347 1.00 79.05  ? 253 ALA B N   1 
ATOM   4931 C CA  . ALA B 1 253 ? 165.983 155.838 148.644 1.00 79.05  ? 253 ALA B CA  1 
ATOM   4932 C C   . ALA B 1 253 ? 165.267 157.181 148.722 1.00 79.05  ? 253 ALA B C   1 
ATOM   4933 O O   . ALA B 1 253 ? 164.127 157.259 149.199 1.00 79.05  ? 253 ALA B O   1 
ATOM   4934 C CB  . ALA B 1 253 ? 167.013 155.713 149.764 1.00 79.05  ? 253 ALA B CB  1 
ATOM   4935 N N   . VAL B 1 254 ? 165.917 158.249 148.251 1.00 78.56  ? 254 VAL B N   1 
ATOM   4936 C CA  . VAL B 1 254 ? 165.300 159.573 148.305 1.00 78.56  ? 254 VAL B CA  1 
ATOM   4937 C C   . VAL B 1 254 ? 164.051 159.615 147.436 1.00 78.56  ? 254 VAL B C   1 
ATOM   4938 O O   . VAL B 1 254 ? 163.006 160.137 147.848 1.00 78.56  ? 254 VAL B O   1 
ATOM   4939 C CB  . VAL B 1 254 ? 166.315 160.656 147.895 1.00 78.56  ? 254 VAL B CB  1 
ATOM   4940 C CG1 . VAL B 1 254 ? 165.614 161.982 147.677 1.00 78.56  ? 254 VAL B CG1 1 
ATOM   4941 C CG2 . VAL B 1 254 ? 167.397 160.794 148.949 1.00 78.56  ? 254 VAL B CG2 1 
ATOM   4942 N N   . PHE B 1 255 ? 164.132 159.060 146.223 1.00 85.53  ? 255 PHE B N   1 
ATOM   4943 C CA  . PHE B 1 255 ? 162.974 159.059 145.337 1.00 85.53  ? 255 PHE B CA  1 
ATOM   4944 C C   . PHE B 1 255 ? 161.822 158.263 145.933 1.00 85.53  ? 255 PHE B C   1 
ATOM   4945 O O   . PHE B 1 255 ? 160.667 158.696 145.869 1.00 85.53  ? 255 PHE B O   1 
ATOM   4946 C CB  . PHE B 1 255 ? 163.354 158.501 143.966 1.00 85.53  ? 255 PHE B CB  1 
ATOM   4947 C CG  . PHE B 1 255 ? 162.218 158.485 142.987 1.00 85.53  ? 255 PHE B CG  1 
ATOM   4948 C CD1 . PHE B 1 255 ? 161.859 159.633 142.304 1.00 85.53  ? 255 PHE B CD1 1 
ATOM   4949 C CD2 . PHE B 1 255 ? 161.504 157.323 142.751 1.00 85.53  ? 255 PHE B CD2 1 
ATOM   4950 C CE1 . PHE B 1 255 ? 160.810 159.623 141.404 1.00 85.53  ? 255 PHE B CE1 1 
ATOM   4951 C CE2 . PHE B 1 255 ? 160.455 157.306 141.853 1.00 85.53  ? 255 PHE B CE2 1 
ATOM   4952 C CZ  . PHE B 1 255 ? 160.108 158.457 141.178 1.00 85.53  ? 255 PHE B CZ  1 
ATOM   4953 N N   . ALA B 1 256 ? 162.112 157.097 146.515 1.00 88.95  ? 256 ALA B N   1 
ATOM   4954 C CA  . ALA B 1 256 ? 161.056 156.291 147.118 1.00 88.95  ? 256 ALA B CA  1 
ATOM   4955 C C   . ALA B 1 256 ? 160.396 157.028 148.275 1.00 88.95  ? 256 ALA B C   1 
ATOM   4956 O O   . ALA B 1 256 ? 159.164 157.065 148.383 1.00 88.95  ? 256 ALA B O   1 
ATOM   4957 C CB  . ALA B 1 256 ? 161.624 154.953 147.590 1.00 88.95  ? 256 ALA B CB  1 
ATOM   4958 N N   . PHE B 1 257 ? 161.206 157.633 149.149 1.00 91.58  ? 257 PHE B N   1 
ATOM   4959 C CA  . PHE B 1 257 ? 160.652 158.348 150.293 1.00 91.58  ? 257 PHE B CA  1 
ATOM   4960 C C   . PHE B 1 257 ? 159.806 159.532 149.846 1.00 91.58  ? 257 PHE B C   1 
ATOM   4961 O O   . PHE B 1 257 ? 158.775 159.833 150.457 1.00 91.58  ? 257 PHE B O   1 
ATOM   4962 C CB  . PHE B 1 257 ? 161.780 158.807 151.217 1.00 91.58  ? 257 PHE B CB  1 
ATOM   4963 C CG  . PHE B 1 257 ? 161.326 159.694 152.342 1.00 91.58  ? 257 PHE B CG  1 
ATOM   4964 C CD1 . PHE B 1 257 ? 160.740 159.154 153.474 1.00 91.58  ? 257 PHE B CD1 1 
ATOM   4965 C CD2 . PHE B 1 257 ? 161.500 161.067 152.275 1.00 91.58  ? 257 PHE B CD2 1 
ATOM   4966 C CE1 . PHE B 1 257 ? 160.327 159.966 154.514 1.00 91.58  ? 257 PHE B CE1 1 
ATOM   4967 C CE2 . PHE B 1 257 ? 161.089 161.884 153.311 1.00 91.58  ? 257 PHE B CE2 1 
ATOM   4968 C CZ  . PHE B 1 257 ? 160.502 161.333 154.432 1.00 91.58  ? 257 PHE B CZ  1 
ATOM   4969 N N   . SER B 1 258 ? 160.225 160.219 148.780 1.00 93.51  ? 258 SER B N   1 
ATOM   4970 C CA  . SER B 1 258 ? 159.465 161.373 148.309 1.00 93.51  ? 258 SER B CA  1 
ATOM   4971 C C   . SER B 1 258 ? 158.176 160.952 147.613 1.00 93.51  ? 258 SER B C   1 
ATOM   4972 O O   . SER B 1 258 ? 157.148 161.626 147.745 1.00 93.51  ? 258 SER B O   1 
ATOM   4973 C CB  . SER B 1 258 ? 160.324 162.220 147.374 1.00 93.51  ? 258 SER B CB  1 
ATOM   4974 O OG  . SER B 1 258 ? 160.475 161.592 146.114 1.00 93.51  ? 258 SER B OG  1 
ATOM   4975 N N   . ILE B 1 259 ? 158.205 159.844 146.865 1.00 99.44  ? 259 ILE B N   1 
ATOM   4976 C CA  . ILE B 1 259 ? 157.040 159.432 146.084 1.00 99.44  ? 259 ILE B CA  1 
ATOM   4977 C C   . ILE B 1 259 ? 156.045 158.625 146.908 1.00 99.44  ? 259 ILE B C   1 
ATOM   4978 O O   . ILE B 1 259 ? 154.892 158.459 146.480 1.00 99.44  ? 259 ILE B O   1 
ATOM   4979 C CB  . ILE B 1 259 ? 157.481 158.618 144.848 1.00 99.44  ? 259 ILE B CB  1 
ATOM   4980 C CG1 . ILE B 1 259 ? 156.333 158.455 143.851 1.00 99.44  ? 259 ILE B CG1 1 
ATOM   4981 C CG2 . ILE B 1 259 ? 157.961 157.240 145.262 1.00 99.44  ? 259 ILE B CG2 1 
ATOM   4982 C CD1 . ILE B 1 259 ? 155.890 159.754 143.223 1.00 99.44  ? 259 ILE B CD1 1 
ATOM   4983 N N   . GLY B 1 260 ? 156.444 158.132 148.081 1.00 106.58 ? 260 GLY B N   1 
ATOM   4984 C CA  . GLY B 1 260 ? 155.567 157.343 148.914 1.00 106.58 ? 260 GLY B CA  1 
ATOM   4985 C C   . GLY B 1 260 ? 154.242 158.007 149.233 1.00 106.58 ? 260 GLY B C   1 
ATOM   4986 O O   . GLY B 1 260 ? 153.182 157.561 148.784 1.00 106.58 ? 260 GLY B O   1 
ATOM   4987 N N   . PRO B 1 261 ? 154.271 159.085 150.022 1.00 109.30 ? 261 PRO B N   1 
ATOM   4988 C CA  . PRO B 1 261 ? 153.007 159.743 150.397 1.00 109.30 ? 261 PRO B CA  1 
ATOM   4989 C C   . PRO B 1 261 ? 152.219 160.285 149.218 1.00 109.30 ? 261 PRO B C   1 
ATOM   4990 O O   . PRO B 1 261 ? 150.983 160.293 149.265 1.00 109.30 ? 261 PRO B O   1 
ATOM   4991 C CB  . PRO B 1 261 ? 153.465 160.870 151.335 1.00 109.30 ? 261 PRO B CB  1 
ATOM   4992 C CG  . PRO B 1 261 ? 154.906 161.087 151.006 1.00 109.30 ? 261 PRO B CG  1 
ATOM   4993 C CD  . PRO B 1 261 ? 155.436 159.736 150.643 1.00 109.30 ? 261 PRO B CD  1 
ATOM   4994 N N   . GLU B 1 262 ? 152.894 160.743 148.161 1.00 110.01 ? 262 GLU B N   1 
ATOM   4995 C CA  . GLU B 1 262 ? 152.191 161.373 147.047 1.00 110.01 ? 262 GLU B CA  1 
ATOM   4996 C C   . GLU B 1 262 ? 151.316 160.374 146.299 1.00 110.01 ? 262 GLU B C   1 
ATOM   4997 O O   . GLU B 1 262 ? 150.129 160.627 146.065 1.00 110.01 ? 262 GLU B O   1 
ATOM   4998 C CB  . GLU B 1 262 ? 153.195 162.021 146.095 1.00 110.01 ? 262 GLU B CB  1 
ATOM   4999 C CG  . GLU B 1 262 ? 152.556 162.681 144.885 1.00 110.01 ? 262 GLU B CG  1 
ATOM   5000 C CD  . GLU B 1 262 ? 153.580 163.231 143.914 1.00 110.01 ? 262 GLU B CD  1 
ATOM   5001 O OE1 . GLU B 1 262 ? 154.790 163.047 144.155 1.00 110.01 ? 262 GLU B OE1 1 
ATOM   5002 O OE2 . GLU B 1 262 ? 153.174 163.843 142.905 1.00 110.01 ? 262 GLU B OE2 1 
ATOM   5003 N N   . LYS B 1 263 ? 151.883 159.233 145.914 1.00 112.11 ? 263 LYS B N   1 
ATOM   5004 C CA  . LYS B 1 263 ? 151.176 158.246 145.110 1.00 112.11 ? 263 LYS B CA  1 
ATOM   5005 C C   . LYS B 1 263 ? 150.794 157.002 145.901 1.00 112.11 ? 263 LYS B C   1 
ATOM   5006 O O   . LYS B 1 263 ? 150.379 156.004 145.304 1.00 112.11 ? 263 LYS B O   1 
ATOM   5007 C CB  . LYS B 1 263 ? 152.021 157.858 143.894 1.00 112.11 ? 263 LYS B CB  1 
ATOM   5008 C CG  . LYS B 1 263 ? 151.207 157.590 142.637 1.00 112.11 ? 263 LYS B CG  1 
ATOM   5009 C CD  . LYS B 1 263 ? 152.097 157.458 141.414 1.00 112.11 ? 263 LYS B CD  1 
ATOM   5010 C CE  . LYS B 1 263 ? 151.274 157.196 140.163 1.00 112.11 ? 263 LYS B CE  1 
ATOM   5011 N NZ  . LYS B 1 263 ? 152.124 157.079 138.946 1.00 112.11 ? 263 LYS B NZ  1 
ATOM   5012 N N   . GLY B 1 264 ? 150.922 157.035 147.224 1.00 114.09 ? 264 GLY B N   1 
ATOM   5013 C CA  . GLY B 1 264 ? 150.583 155.883 148.035 1.00 114.09 ? 264 GLY B CA  1 
ATOM   5014 C C   . GLY B 1 264 ? 151.708 154.873 148.120 1.00 114.09 ? 264 GLY B C   1 
ATOM   5015 O O   . GLY B 1 264 ? 152.437 154.662 147.146 1.00 114.09 ? 264 GLY B O   1 
ATOM   5016 N N   . TRP B 1 265 ? 151.861 154.244 149.279 1.00 117.16 ? 265 TRP B N   1 
ATOM   5017 C CA  . TRP B 1 265 ? 152.913 153.260 149.466 1.00 117.16 ? 265 TRP B CA  1 
ATOM   5018 C C   . TRP B 1 265 ? 152.578 151.972 148.719 1.00 117.16 ? 265 TRP B C   1 
ATOM   5019 O O   . TRP B 1 265 ? 151.447 151.760 148.273 1.00 117.16 ? 265 TRP B O   1 
ATOM   5020 C CB  . TRP B 1 265 ? 153.127 152.974 150.954 1.00 117.16 ? 265 TRP B CB  1 
ATOM   5021 C CG  . TRP B 1 265 ? 153.260 154.212 151.797 1.00 117.16 ? 265 TRP B CG  1 
ATOM   5022 C CD1 . TRP B 1 265 ? 153.664 155.448 151.383 1.00 117.16 ? 265 TRP B CD1 1 
ATOM   5023 C CD2 . TRP B 1 265 ? 152.986 154.330 153.199 1.00 117.16 ? 265 TRP B CD2 1 
ATOM   5024 N NE1 . TRP B 1 265 ? 153.658 156.327 152.438 1.00 117.16 ? 265 TRP B NE1 1 
ATOM   5025 C CE2 . TRP B 1 265 ? 153.246 155.666 153.565 1.00 117.16 ? 265 TRP B CE2 1 
ATOM   5026 C CE3 . TRP B 1 265 ? 152.545 153.436 154.179 1.00 117.16 ? 265 TRP B CE3 1 
ATOM   5027 C CZ2 . TRP B 1 265 ? 153.081 156.128 154.869 1.00 117.16 ? 265 TRP B CZ2 1 
ATOM   5028 C CZ3 . TRP B 1 265 ? 152.383 153.897 155.473 1.00 117.16 ? 265 TRP B CZ3 1 
ATOM   5029 C CH2 . TRP B 1 265 ? 152.650 155.231 155.806 1.00 117.16 ? 265 TRP B CH2 1 
ATOM   5030 N N   . MET B 1 266 ? 153.596 151.116 148.582 1.00 117.93 ? 266 MET B N   1 
ATOM   5031 C CA  . MET B 1 266 ? 153.539 149.825 147.893 1.00 117.93 ? 266 MET B CA  1 
ATOM   5032 C C   . MET B 1 266 ? 152.622 149.835 146.671 1.00 117.93 ? 266 MET B C   1 
ATOM   5033 O O   . MET B 1 266 ? 151.861 148.890 146.441 1.00 117.93 ? 266 MET B O   1 
ATOM   5034 C CB  . MET B 1 266 ? 153.169 148.688 148.867 1.00 117.93 ? 266 MET B CB  1 
ATOM   5035 C CG  . MET B 1 266 ? 151.726 148.573 149.408 1.00 117.93 ? 266 MET B CG  1 
ATOM   5036 S SD  . MET B 1 266 ? 151.138 149.828 150.562 1.00 117.93 ? 266 MET B SD  1 
ATOM   5037 C CE  . MET B 1 266 ? 152.129 149.456 152.008 1.00 117.93 ? 266 MET B CE  1 
ATOM   5038 N N   . SER B 1 267 ? 152.717 150.886 145.860 1.00 115.44 ? 267 SER B N   1 
ATOM   5039 C CA  . SER B 1 267 ? 151.844 151.084 144.709 1.00 115.44 ? 267 SER B CA  1 
ATOM   5040 C C   . SER B 1 267 ? 152.610 151.009 143.391 1.00 115.44 ? 267 SER B C   1 
ATOM   5041 O O   . SER B 1 267 ? 152.378 151.800 142.475 1.00 115.44 ? 267 SER B O   1 
ATOM   5042 C CB  . SER B 1 267 ? 151.106 152.414 144.821 1.00 115.44 ? 267 SER B CB  1 
ATOM   5043 O OG  . SER B 1 267 ? 150.106 152.356 145.823 1.00 115.44 ? 267 SER B OG  1 
ATOM   5044 N N   . GLY B 1 268 ? 153.534 150.057 143.280 1.00 111.79 ? 268 GLY B N   1 
ATOM   5045 C CA  . GLY B 1 268 ? 154.242 149.841 142.033 1.00 111.79 ? 268 GLY B CA  1 
ATOM   5046 C C   . GLY B 1 268 ? 155.561 150.577 141.925 1.00 111.79 ? 268 GLY B C   1 
ATOM   5047 O O   . GLY B 1 268 ? 156.619 149.951 141.816 1.00 111.79 ? 268 GLY B O   1 
ATOM   5048 N N   . ILE B 1 269 ? 155.514 151.909 141.937 1.00 108.98 ? 269 ILE B N   1 
ATOM   5049 C CA  . ILE B 1 269 ? 156.746 152.688 141.872 1.00 108.98 ? 269 ILE B CA  1 
ATOM   5050 C C   . ILE B 1 269 ? 157.526 152.561 143.175 1.00 108.98 ? 269 ILE B C   1 
ATOM   5051 O O   . ILE B 1 269 ? 158.755 152.401 143.167 1.00 108.98 ? 269 ILE B O   1 
ATOM   5052 C CB  . ILE B 1 269 ? 156.432 154.159 141.543 1.00 108.98 ? 269 ILE B CB  1 
ATOM   5053 C CG1 . ILE B 1 269 ? 155.472 154.252 140.356 1.00 108.98 ? 269 ILE B CG1 1 
ATOM   5054 C CG2 . ILE B 1 269 ? 157.712 154.921 141.246 1.00 108.98 ? 269 ILE B CG2 1 
ATOM   5055 C CD1 . ILE B 1 269 ? 156.075 153.805 139.043 1.00 108.98 ? 269 ILE B CD1 1 
ATOM   5056 N N   . THR B 1 270 ? 156.828 152.630 144.311 1.00 105.82 ? 270 THR B N   1 
ATOM   5057 C CA  . THR B 1 270 ? 157.506 152.612 145.603 1.00 105.82 ? 270 THR B CA  1 
ATOM   5058 C C   . THR B 1 270 ? 158.223 151.289 145.840 1.00 105.82 ? 270 THR B C   1 
ATOM   5059 O O   . THR B 1 270 ? 159.367 151.273 146.307 1.00 105.82 ? 270 THR B O   1 
ATOM   5060 C CB  . THR B 1 270 ? 156.506 152.886 146.726 1.00 105.82 ? 270 THR B CB  1 
ATOM   5061 O OG1 . THR B 1 270 ? 155.861 154.144 146.495 1.00 105.82 ? 270 THR B OG1 1 
ATOM   5062 C CG2 . THR B 1 270 ? 157.216 152.936 148.068 1.00 105.82 ? 270 THR B CG2 1 
ATOM   5063 N N   . ILE B 1 271 ? 157.571 150.169 145.521 1.00 105.41 ? 271 ILE B N   1 
ATOM   5064 C CA  . ILE B 1 271 ? 158.191 148.868 145.751 1.00 105.41 ? 271 ILE B CA  1 
ATOM   5065 C C   . ILE B 1 271 ? 159.416 148.693 144.862 1.00 105.41 ? 271 ILE B C   1 
ATOM   5066 O O   . ILE B 1 271 ? 160.447 148.175 145.305 1.00 105.41 ? 271 ILE B O   1 
ATOM   5067 C CB  . ILE B 1 271 ? 157.171 147.734 145.547 1.00 105.41 ? 271 ILE B CB  1 
ATOM   5068 C CG1 . ILE B 1 271 ? 156.407 147.916 144.234 1.00 105.41 ? 271 ILE B CG1 1 
ATOM   5069 C CG2 . ILE B 1 271 ? 156.215 147.660 146.727 1.00 105.41 ? 271 ILE B CG2 1 
ATOM   5070 C CD1 . ILE B 1 271 ? 155.603 146.703 143.817 1.00 105.41 ? 271 ILE B CD1 1 
ATOM   5071 N N   . GLY B 1 272 ? 159.327 149.117 143.600 1.00 100.05 ? 272 GLY B N   1 
ATOM   5072 C CA  . GLY B 1 272 ? 160.477 149.010 142.716 1.00 100.05 ? 272 GLY B CA  1 
ATOM   5073 C C   . GLY B 1 272 ? 161.642 149.869 143.169 1.00 100.05 ? 272 GLY B C   1 
ATOM   5074 O O   . GLY B 1 272 ? 162.796 149.428 143.156 1.00 100.05 ? 272 GLY B O   1 
ATOM   5075 N N   . SER B 1 273 ? 161.357 151.107 143.582 1.00 97.24  ? 273 SER B N   1 
ATOM   5076 C CA  . SER B 1 273 ? 162.417 151.979 144.076 1.00 97.24  ? 273 SER B CA  1 
ATOM   5077 C C   . SER B 1 273 ? 163.050 151.416 145.343 1.00 97.24  ? 273 SER B C   1 
ATOM   5078 O O   . SER B 1 273 ? 164.275 151.463 145.506 1.00 97.24  ? 273 SER B O   1 
ATOM   5079 C CB  . SER B 1 273 ? 161.869 153.383 144.321 1.00 97.24  ? 273 SER B CB  1 
ATOM   5080 O OG  . SER B 1 273 ? 160.629 153.329 145.001 1.00 97.24  ? 273 SER B OG  1 
ATOM   5081 N N   . GLY B 1 274 ? 162.236 150.874 146.252 1.00 94.93  ? 274 GLY B N   1 
ATOM   5082 C CA  . GLY B 1 274 ? 162.788 150.265 147.452 1.00 94.93  ? 274 GLY B CA  1 
ATOM   5083 C C   . GLY B 1 274 ? 163.640 149.046 147.151 1.00 94.93  ? 274 GLY B C   1 
ATOM   5084 O O   . GLY B 1 274 ? 164.691 148.844 147.765 1.00 94.93  ? 274 GLY B O   1 
ATOM   5085 N N   . LEU B 1 275 ? 163.195 148.214 146.207 1.00 94.63  ? 275 LEU B N   1 
ATOM   5086 C CA  . LEU B 1 275 ? 163.996 147.065 145.800 1.00 94.63  ? 275 LEU B CA  1 
ATOM   5087 C C   . LEU B 1 275 ? 165.335 147.509 145.231 1.00 94.63  ? 275 LEU B C   1 
ATOM   5088 O O   . LEU B 1 275 ? 166.382 146.941 145.570 1.00 94.63  ? 275 LEU B O   1 
ATOM   5089 C CB  . LEU B 1 275 ? 163.229 146.229 144.776 1.00 94.63  ? 275 LEU B CB  1 
ATOM   5090 C CG  . LEU B 1 275 ? 164.011 145.111 144.081 1.00 94.63  ? 275 LEU B CG  1 
ATOM   5091 C CD1 . LEU B 1 275 ? 164.329 143.986 145.054 1.00 94.63  ? 275 LEU B CD1 1 
ATOM   5092 C CD2 . LEU B 1 275 ? 163.250 144.584 142.873 1.00 94.63  ? 275 LEU B CD2 1 
ATOM   5093 N N   . VAL B 1 276 ? 165.322 148.533 144.374 1.00 90.08  ? 276 VAL B N   1 
ATOM   5094 C CA  . VAL B 1 276 ? 166.568 149.045 143.809 1.00 90.08  ? 276 VAL B CA  1 
ATOM   5095 C C   . VAL B 1 276 ? 167.475 149.574 144.912 1.00 90.08  ? 276 VAL B C   1 
ATOM   5096 O O   . VAL B 1 276 ? 168.686 149.321 144.915 1.00 90.08  ? 276 VAL B O   1 
ATOM   5097 C CB  . VAL B 1 276 ? 166.270 150.124 142.750 1.00 90.08  ? 276 VAL B CB  1 
ATOM   5098 C CG1 . VAL B 1 276 ? 167.501 150.974 142.493 1.00 90.08  ? 276 VAL B CG1 1 
ATOM   5099 C CG2 . VAL B 1 276 ? 165.788 149.480 141.463 1.00 90.08  ? 276 VAL B CG2 1 
ATOM   5100 N N   . ALA B 1 277 ? 166.903 150.305 145.872 1.00 88.28  ? 277 ALA B N   1 
ATOM   5101 C CA  . ALA B 1 277 ? 167.703 150.878 146.949 1.00 88.28  ? 277 ALA B CA  1 
ATOM   5102 C C   . ALA B 1 277 ? 168.364 149.793 147.789 1.00 88.28  ? 277 ALA B C   1 
ATOM   5103 O O   . ALA B 1 277 ? 169.567 149.857 148.070 1.00 88.28  ? 277 ALA B O   1 
ATOM   5104 C CB  . ALA B 1 277 ? 166.832 151.779 147.824 1.00 88.28  ? 277 ALA B CB  1 
ATOM   5105 N N   . LEU B 1 278 ? 167.594 148.782 148.201 1.00 87.78  ? 278 LEU B N   1 
ATOM   5106 C CA  . LEU B 1 278 ? 168.169 147.712 149.016 1.00 87.78  ? 278 LEU B CA  1 
ATOM   5107 C C   . LEU B 1 278 ? 169.203 146.903 148.242 1.00 87.78  ? 278 LEU B C   1 
ATOM   5108 O O   . LEU B 1 278 ? 170.253 146.547 148.792 1.00 87.78  ? 278 LEU B O   1 
ATOM   5109 C CB  . LEU B 1 278 ? 167.074 146.800 149.569 1.00 87.78  ? 278 LEU B CB  1 
ATOM   5110 C CG  . LEU B 1 278 ? 166.352 147.233 150.850 1.00 87.78  ? 278 LEU B CG  1 
ATOM   5111 C CD1 . LEU B 1 278 ? 167.348 147.270 152.000 1.00 87.78  ? 278 LEU B CD1 1 
ATOM   5112 C CD2 . LEU B 1 278 ? 165.641 148.570 150.724 1.00 87.78  ? 278 LEU B CD2 1 
ATOM   5113 N N   . ALA B 1 279 ? 168.931 146.594 146.971 1.00 85.46  ? 279 ALA B N   1 
ATOM   5114 C CA  . ALA B 1 279 ? 169.903 145.844 146.184 1.00 85.46  ? 279 ALA B CA  1 
ATOM   5115 C C   . ALA B 1 279 ? 171.202 146.623 146.032 1.00 85.46  ? 279 ALA B C   1 
ATOM   5116 O O   . ALA B 1 279 ? 172.295 146.063 146.189 1.00 85.46  ? 279 ALA B O   1 
ATOM   5117 C CB  . ALA B 1 279 ? 169.319 145.499 144.815 1.00 85.46  ? 279 ALA B CB  1 
ATOM   5118 N N   . ALA B 1 280 ? 171.102 147.924 145.745 1.00 82.84  ? 280 ALA B N   1 
ATOM   5119 C CA  . ALA B 1 280 ? 172.297 148.744 145.606 1.00 82.84  ? 280 ALA B CA  1 
ATOM   5120 C C   . ALA B 1 280 ? 173.056 148.841 146.922 1.00 82.84  ? 280 ALA B C   1 
ATOM   5121 O O   . ALA B 1 280 ? 174.289 148.784 146.936 1.00 82.84  ? 280 ALA B O   1 
ATOM   5122 C CB  . ALA B 1 280 ? 171.921 150.132 145.094 1.00 82.84  ? 280 ALA B CB  1 
ATOM   5123 N N   . ALA B 1 281 ? 172.340 148.986 148.040 1.00 83.01  ? 281 ALA B N   1 
ATOM   5124 C CA  . ALA B 1 281 ? 173.009 149.080 149.335 1.00 83.01  ? 281 ALA B CA  1 
ATOM   5125 C C   . ALA B 1 281 ? 173.745 147.791 149.676 1.00 83.01  ? 281 ALA B C   1 
ATOM   5126 O O   . ALA B 1 281 ? 174.886 147.826 150.152 1.00 83.01  ? 281 ALA B O   1 
ATOM   5127 C CB  . ALA B 1 281 ? 171.996 149.421 150.426 1.00 83.01  ? 281 ALA B CB  1 
ATOM   5128 N N   . VAL B 1 282 ? 173.110 146.641 149.439 1.00 82.84  ? 282 VAL B N   1 
ATOM   5129 C CA  . VAL B 1 282 ? 173.756 145.365 149.733 1.00 82.84  ? 282 VAL B CA  1 
ATOM   5130 C C   . VAL B 1 282 ? 174.970 145.157 148.836 1.00 82.84  ? 282 VAL B C   1 
ATOM   5131 O O   . VAL B 1 282 ? 176.032 144.716 149.297 1.00 82.84  ? 282 VAL B O   1 
ATOM   5132 C CB  . VAL B 1 282 ? 172.745 144.213 149.603 1.00 82.84  ? 282 VAL B CB  1 
ATOM   5133 C CG1 . VAL B 1 282 ? 173.463 142.877 149.575 1.00 82.84  ? 282 VAL B CG1 1 
ATOM   5134 C CG2 . VAL B 1 282 ? 171.750 144.260 150.749 1.00 82.84  ? 282 VAL B CG2 1 
ATOM   5135 N N   . ALA B 1 283 ? 174.841 145.473 147.544 1.00 81.97  ? 283 ALA B N   1 
ATOM   5136 C CA  . ALA B 1 283 ? 175.982 145.346 146.645 1.00 81.97  ? 283 ALA B CA  1 
ATOM   5137 C C   . ALA B 1 283 ? 177.117 146.271 147.061 1.00 81.97  ? 283 ALA B C   1 
ATOM   5138 O O   . ALA B 1 283 ? 178.290 145.890 147.000 1.00 81.97  ? 283 ALA B O   1 
ATOM   5139 C CB  . ALA B 1 283 ? 175.555 145.631 145.206 1.00 81.97  ? 283 ALA B CB  1 
ATOM   5140 N N   . PHE B 1 284 ? 176.787 147.492 147.488 1.00 80.27  ? 284 PHE B N   1 
ATOM   5141 C CA  . PHE B 1 284 ? 177.806 148.430 147.947 1.00 80.27  ? 284 PHE B CA  1 
ATOM   5142 C C   . PHE B 1 284 ? 178.519 147.907 149.185 1.00 80.27  ? 284 PHE B C   1 
ATOM   5143 O O   . PHE B 1 284 ? 179.749 147.988 149.283 1.00 80.27  ? 284 PHE B O   1 
ATOM   5144 C CB  . PHE B 1 284 ? 177.160 149.788 148.226 1.00 80.27  ? 284 PHE B CB  1 
ATOM   5145 C CG  . PHE B 1 284 ? 178.093 150.800 148.825 1.00 80.27  ? 284 PHE B CG  1 
ATOM   5146 C CD1 . PHE B 1 284 ? 179.060 151.415 148.051 1.00 80.27  ? 284 PHE B CD1 1 
ATOM   5147 C CD2 . PHE B 1 284 ? 177.987 151.150 150.160 1.00 80.27  ? 284 PHE B CD2 1 
ATOM   5148 C CE1 . PHE B 1 284 ? 179.911 152.352 148.600 1.00 80.27  ? 284 PHE B CE1 1 
ATOM   5149 C CE2 . PHE B 1 284 ? 178.837 152.085 150.713 1.00 80.27  ? 284 PHE B CE2 1 
ATOM   5150 C CZ  . PHE B 1 284 ? 179.799 152.687 149.931 1.00 80.27  ? 284 PHE B CZ  1 
ATOM   5151 N N   . VAL B 1 285 ? 177.763 147.360 150.139 1.00 81.05  ? 285 VAL B N   1 
ATOM   5152 C CA  . VAL B 1 285 ? 178.368 146.829 151.357 1.00 81.05  ? 285 VAL B CA  1 
ATOM   5153 C C   . VAL B 1 285 ? 179.288 145.660 151.028 1.00 81.05  ? 285 VAL B C   1 
ATOM   5154 O O   . VAL B 1 285 ? 180.383 145.536 151.589 1.00 81.05  ? 285 VAL B O   1 
ATOM   5155 C CB  . VAL B 1 285 ? 177.276 146.431 152.367 1.00 81.05  ? 285 VAL B CB  1 
ATOM   5156 C CG1 . VAL B 1 285 ? 177.865 145.602 153.491 1.00 81.05  ? 285 VAL B CG1 1 
ATOM   5157 C CG2 . VAL B 1 285 ? 176.598 147.668 152.924 1.00 81.05  ? 285 VAL B CG2 1 
ATOM   5158 N N   . ILE B 1 286 ? 178.861 144.787 150.113 1.00 83.07  ? 286 ILE B N   1 
ATOM   5159 C CA  . ILE B 1 286 ? 179.697 143.654 149.719 1.00 83.07  ? 286 ILE B CA  1 
ATOM   5160 C C   . ILE B 1 286 ? 180.966 144.134 149.024 1.00 83.07  ? 286 ILE B C   1 
ATOM   5161 O O   . ILE B 1 286 ? 182.068 143.647 149.306 1.00 83.07  ? 286 ILE B O   1 
ATOM   5162 C CB  . ILE B 1 286 ? 178.897 142.685 148.829 1.00 83.07  ? 286 ILE B CB  1 
ATOM   5163 C CG1 . ILE B 1 286 ? 177.850 141.938 149.657 1.00 83.07  ? 286 ILE B CG1 1 
ATOM   5164 C CG2 . ILE B 1 286 ? 179.827 141.708 148.129 1.00 83.07  ? 286 ILE B CG2 1 
ATOM   5165 C CD1 . ILE B 1 286 ? 176.971 141.027 148.837 1.00 83.07  ? 286 ILE B CD1 1 
ATOM   5166 N N   . VAL B 1 287 ? 180.835 145.094 148.106 1.00 82.24  ? 287 VAL B N   1 
ATOM   5167 C CA  . VAL B 1 287 ? 181.976 145.537 147.312 1.00 82.24  ? 287 VAL B CA  1 
ATOM   5168 C C   . VAL B 1 287 ? 182.985 146.288 148.176 1.00 82.24  ? 287 VAL B C   1 
ATOM   5169 O O   . VAL B 1 287 ? 184.200 146.162 147.984 1.00 82.24  ? 287 VAL B O   1 
ATOM   5170 C CB  . VAL B 1 287 ? 181.491 146.390 146.125 1.00 82.24  ? 287 VAL B CB  1 
ATOM   5171 C CG1 . VAL B 1 287 ? 182.639 147.180 145.517 1.00 82.24  ? 287 VAL B CG1 1 
ATOM   5172 C CG2 . VAL B 1 287 ? 180.850 145.506 145.075 1.00 82.24  ? 287 VAL B CG2 1 
ATOM   5173 N N   . GLU B 1 288 ? 182.505 147.068 149.147 1.00 83.19  ? 288 GLU B N   1 
ATOM   5174 C CA  . GLU B 1 288 ? 183.383 147.952 149.904 1.00 83.19  ? 288 GLU B CA  1 
ATOM   5175 C C   . GLU B 1 288 ? 184.374 147.207 150.791 1.00 83.19  ? 288 GLU B C   1 
ATOM   5176 O O   . GLU B 1 288 ? 185.302 147.835 151.310 1.00 83.19  ? 288 GLU B O   1 
ATOM   5177 C CB  . GLU B 1 288 ? 182.543 148.899 150.760 1.00 83.19  ? 288 GLU B CB  1 
ATOM   5178 C CG  . GLU B 1 288 ? 182.269 150.242 150.108 1.00 83.19  ? 288 GLU B CG  1 
ATOM   5179 C CD  . GLU B 1 288 ? 183.530 150.923 149.625 1.00 83.19  ? 288 GLU B CD  1 
ATOM   5180 O OE1 . GLU B 1 288 ? 184.470 151.062 150.430 1.00 83.19  ? 288 GLU B OE1 1 
ATOM   5181 O OE2 . GLU B 1 288 ? 183.580 151.325 148.444 1.00 83.19  ? 288 GLU B OE2 1 
ATOM   5182 N N   . ARG B 1 289 ? 184.204 145.898 150.980 1.00 87.63  ? 289 ARG B N   1 
ATOM   5183 C CA  . ARG B 1 289 ? 185.083 145.138 151.860 1.00 87.63  ? 289 ARG B CA  1 
ATOM   5184 C C   . ARG B 1 289 ? 186.482 144.940 151.291 1.00 87.63  ? 289 ARG B C   1 
ATOM   5185 O O   . ARG B 1 289 ? 187.377 144.530 152.036 1.00 87.63  ? 289 ARG B O   1 
ATOM   5186 C CB  . ARG B 1 289 ? 184.459 143.775 152.165 1.00 87.63  ? 289 ARG B CB  1 
ATOM   5187 C CG  . ARG B 1 289 ? 183.217 143.843 153.037 1.00 87.63  ? 289 ARG B CG  1 
ATOM   5188 C CD  . ARG B 1 289 ? 182.946 142.513 153.717 1.00 87.63  ? 289 ARG B CD  1 
ATOM   5189 N NE  . ARG B 1 289 ? 181.955 141.726 152.993 1.00 87.63  ? 289 ARG B NE  1 
ATOM   5190 C CZ  . ARG B 1 289 ? 182.108 140.453 152.659 1.00 87.63  ? 289 ARG B CZ  1 
ATOM   5191 N NH1 . ARG B 1 289 ? 183.206 139.784 152.971 1.00 87.63  ? 289 ARG B NH1 1 
ATOM   5192 N NH2 . ARG B 1 289 ? 181.136 139.834 151.996 1.00 87.63  ? 289 ARG B NH2 1 
ATOM   5193 N N   . THR B 1 290 ? 186.696 145.214 150.001 1.00 87.79  ? 290 THR B N   1 
ATOM   5194 C CA  . THR B 1 290 ? 187.980 144.933 149.369 1.00 87.79  ? 290 THR B CA  1 
ATOM   5195 C C   . THR B 1 290 ? 188.406 146.044 148.414 1.00 87.79  ? 290 THR B C   1 
ATOM   5196 O O   . THR B 1 290 ? 189.176 145.802 147.479 1.00 87.79  ? 290 THR B O   1 
ATOM   5197 C CB  . THR B 1 290 ? 187.935 143.592 148.629 1.00 87.79  ? 290 THR B CB  1 
ATOM   5198 O OG1 . THR B 1 290 ? 189.250 143.242 148.179 1.00 87.79  ? 290 THR B OG1 1 
ATOM   5199 C CG2 . THR B 1 290 ? 186.974 143.651 147.442 1.00 87.79  ? 290 THR B CG2 1 
ATOM   5200 N N   . ALA B 1 291 ? 187.944 147.269 148.646 1.00 86.88  ? 291 ALA B N   1 
ATOM   5201 C CA  . ALA B 1 291 ? 188.195 148.381 147.739 1.00 86.88  ? 291 ALA B CA  1 
ATOM   5202 C C   . ALA B 1 291 ? 189.254 149.309 148.318 1.00 86.88  ? 291 ALA B C   1 
ATOM   5203 O O   . ALA B 1 291 ? 189.170 149.705 149.485 1.00 86.88  ? 291 ALA B O   1 
ATOM   5204 C CB  . ALA B 1 291 ? 186.908 149.159 147.466 1.00 86.88  ? 291 ALA B CB  1 
ATOM   5205 N N   . GLU B 1 292 ? 190.248 149.645 147.502 1.00 87.58  ? 292 GLU B N   1 
ATOM   5206 C CA  . GLU B 1 292 ? 191.239 150.637 147.893 1.00 87.58  ? 292 GLU B CA  1 
ATOM   5207 C C   . GLU B 1 292 ? 190.608 152.023 147.908 1.00 87.58  ? 292 GLU B C   1 
ATOM   5208 O O   . GLU B 1 292 ? 189.780 152.352 147.053 1.00 87.58  ? 292 GLU B O   1 
ATOM   5209 C CB  . GLU B 1 292 ? 192.426 150.607 146.931 1.00 87.58  ? 292 GLU B CB  1 
ATOM   5210 C CG  . GLU B 1 292 ? 193.547 151.563 147.288 1.00 87.58  ? 292 GLU B CG  1 
ATOM   5211 C CD  . GLU B 1 292 ? 194.549 151.728 146.164 1.00 87.58  ? 292 GLU B CD  1 
ATOM   5212 O OE1 . GLU B 1 292 ? 194.345 151.121 145.092 1.00 87.58  ? 292 GLU B OE1 1 
ATOM   5213 O OE2 . GLU B 1 292 ? 195.538 152.465 146.351 1.00 87.58  ? 292 GLU B OE2 1 
ATOM   5214 N N   . ASN B 1 293 ? 191.013 152.842 148.883 1.00 80.44  ? 293 ASN B N   1 
ATOM   5215 C CA  . ASN B 1 293 ? 190.427 154.158 149.118 1.00 80.44  ? 293 ASN B CA  1 
ATOM   5216 C C   . ASN B 1 293 ? 188.914 154.037 149.241 1.00 80.44  ? 293 ASN B C   1 
ATOM   5217 O O   . ASN B 1 293 ? 188.180 154.468 148.343 1.00 80.44  ? 293 ASN B O   1 
ATOM   5218 C CB  . ASN B 1 293 ? 190.797 155.132 147.999 1.00 80.44  ? 293 ASN B CB  1 
ATOM   5219 C CG  . ASN B 1 293 ? 192.270 155.473 147.989 1.00 80.44  ? 293 ASN B CG  1 
ATOM   5220 O OD1 . ASN B 1 293 ? 192.882 155.656 149.039 1.00 80.44  ? 293 ASN B OD1 1 
ATOM   5221 N ND2 . ASN B 1 293 ? 192.847 155.565 146.798 1.00 80.44  ? 293 ASN B ND2 1 
ATOM   5222 N N   . PRO B 1 294 ? 188.415 153.449 150.326 1.00 77.71  ? 294 PRO B N   1 
ATOM   5223 C CA  . PRO B 1 294 ? 186.971 153.222 150.445 1.00 77.71  ? 294 PRO B CA  1 
ATOM   5224 C C   . PRO B 1 294 ? 186.191 154.527 150.454 1.00 77.71  ? 294 PRO B C   1 
ATOM   5225 O O   . PRO B 1 294 ? 186.628 155.531 151.020 1.00 77.71  ? 294 PRO B O   1 
ATOM   5226 C CB  . PRO B 1 294 ? 186.839 152.483 151.782 1.00 77.71  ? 294 PRO B CB  1 
ATOM   5227 C CG  . PRO B 1 294 ? 188.208 151.987 152.101 1.00 77.71  ? 294 PRO B CG  1 
ATOM   5228 C CD  . PRO B 1 294 ? 189.143 152.986 151.516 1.00 77.71  ? 294 PRO B CD  1 
ATOM   5229 N N   . VAL B 1 295 ? 185.021 154.505 149.812 1.00 73.03  ? 295 VAL B N   1 
ATOM   5230 C CA  . VAL B 1 295 ? 184.109 155.638 149.904 1.00 73.03  ? 295 VAL B CA  1 
ATOM   5231 C C   . VAL B 1 295 ? 183.586 155.777 151.327 1.00 73.03  ? 295 VAL B C   1 
ATOM   5232 O O   . VAL B 1 295 ? 183.504 156.885 151.869 1.00 73.03  ? 295 VAL B O   1 
ATOM   5233 C CB  . VAL B 1 295 ? 182.965 155.487 148.886 1.00 73.03  ? 295 VAL B CB  1 
ATOM   5234 C CG1 . VAL B 1 295 ? 181.895 156.536 149.120 1.00 73.03  ? 295 VAL B CG1 1 
ATOM   5235 C CG2 . VAL B 1 295 ? 183.504 155.591 147.475 1.00 73.03  ? 295 VAL B CG2 1 
ATOM   5236 N N   . VAL B 1 296 ? 183.227 154.661 151.952 1.00 73.48  ? 296 VAL B N   1 
ATOM   5237 C CA  . VAL B 1 296 ? 182.804 154.639 153.349 1.00 73.48  ? 296 VAL B CA  1 
ATOM   5238 C C   . VAL B 1 296 ? 183.735 153.712 154.122 1.00 73.48  ? 296 VAL B C   1 
ATOM   5239 O O   . VAL B 1 296 ? 183.652 152.485 153.968 1.00 73.48  ? 296 VAL B O   1 
ATOM   5240 C CB  . VAL B 1 296 ? 181.340 154.195 153.485 1.00 73.48  ? 296 VAL B CB  1 
ATOM   5241 C CG1 . VAL B 1 296 ? 180.979 154.002 154.945 1.00 73.48  ? 296 VAL B CG1 1 
ATOM   5242 C CG2 . VAL B 1 296 ? 180.420 155.212 152.842 1.00 73.48  ? 296 VAL B CG2 1 
ATOM   5243 N N   . PRO B 1 297 ? 184.647 154.239 154.935 1.00 73.49  ? 297 PRO B N   1 
ATOM   5244 C CA  . PRO B 1 297 ? 185.508 153.379 155.759 1.00 73.49  ? 297 PRO B CA  1 
ATOM   5245 C C   . PRO B 1 297 ? 184.761 152.881 156.987 1.00 73.49  ? 297 PRO B C   1 
ATOM   5246 O O   . PRO B 1 297 ? 184.506 153.636 157.930 1.00 73.49  ? 297 PRO B O   1 
ATOM   5247 C CB  . PRO B 1 297 ? 186.670 154.310 156.130 1.00 73.49  ? 297 PRO B CB  1 
ATOM   5248 C CG  . PRO B 1 297 ? 186.082 155.676 156.094 1.00 73.49  ? 297 PRO B CG  1 
ATOM   5249 C CD  . PRO B 1 297 ? 184.993 155.665 155.061 1.00 73.49  ? 297 PRO B CD  1 
ATOM   5250 N N   . PHE B 1 298 ? 184.409 151.594 156.978 1.00 73.36  ? 298 PHE B N   1 
ATOM   5251 C CA  . PHE B 1 298 ? 183.614 151.030 158.064 1.00 73.36  ? 298 PHE B CA  1 
ATOM   5252 C C   . PHE B 1 298 ? 184.432 150.798 159.326 1.00 73.36  ? 298 PHE B C   1 
ATOM   5253 O O   . PHE B 1 298 ? 183.887 150.876 160.433 1.00 73.36  ? 298 PHE B O   1 
ATOM   5254 C CB  . PHE B 1 298 ? 182.966 149.722 157.612 1.00 73.36  ? 298 PHE B CB  1 
ATOM   5255 C CG  . PHE B 1 298 ? 181.927 149.901 156.546 1.00 73.36  ? 298 PHE B CG  1 
ATOM   5256 C CD1 . PHE B 1 298 ? 180.666 150.370 156.863 1.00 73.36  ? 298 PHE B CD1 1 
ATOM   5257 C CD2 . PHE B 1 298 ? 182.213 149.604 155.227 1.00 73.36  ? 298 PHE B CD2 1 
ATOM   5258 C CE1 . PHE B 1 298 ? 179.711 150.536 155.885 1.00 73.36  ? 298 PHE B CE1 1 
ATOM   5259 C CE2 . PHE B 1 298 ? 181.260 149.769 154.245 1.00 73.36  ? 298 PHE B CE2 1 
ATOM   5260 C CZ  . PHE B 1 298 ? 180.009 150.236 154.575 1.00 73.36  ? 298 PHE B CZ  1 
ATOM   5261 N N   . HIS B 1 299 ? 185.732 150.527 159.188 1.00 75.75  ? 299 HIS B N   1 
ATOM   5262 C CA  . HIS B 1 299 ? 186.566 150.255 160.353 1.00 75.75  ? 299 HIS B CA  1 
ATOM   5263 C C   . HIS B 1 299 ? 186.662 151.451 161.289 1.00 75.75  ? 299 HIS B C   1 
ATOM   5264 O O   . HIS B 1 299 ? 187.064 151.289 162.445 1.00 75.75  ? 299 HIS B O   1 
ATOM   5265 C CB  . HIS B 1 299 ? 187.964 149.829 159.910 1.00 75.75  ? 299 HIS B CB  1 
ATOM   5266 C CG  . HIS B 1 299 ? 188.527 150.667 158.807 1.00 75.75  ? 299 HIS B CG  1 
ATOM   5267 N ND1 . HIS B 1 299 ? 188.232 150.446 157.479 1.00 75.75  ? 299 HIS B ND1 1 
ATOM   5268 C CD2 . HIS B 1 299 ? 189.366 151.729 158.834 1.00 75.75  ? 299 HIS B CD2 1 
ATOM   5269 C CE1 . HIS B 1 299 ? 188.866 151.335 156.736 1.00 75.75  ? 299 HIS B CE1 1 
ATOM   5270 N NE2 . HIS B 1 299 ? 189.562 152.125 157.534 1.00 75.75  ? 299 HIS B NE2 1 
ATOM   5271 N N   . LEU B 1 300 ? 186.310 152.648 160.815 1.00 72.43  ? 300 LEU B N   1 
ATOM   5272 C CA  . LEU B 1 300 ? 186.299 153.821 161.678 1.00 72.43  ? 300 LEU B CA  1 
ATOM   5273 C C   . LEU B 1 300 ? 185.136 153.808 162.659 1.00 72.43  ? 300 LEU B C   1 
ATOM   5274 O O   . LEU B 1 300 ? 185.197 154.500 163.680 1.00 72.43  ? 300 LEU B O   1 
ATOM   5275 C CB  . LEU B 1 300 ? 186.239 155.093 160.837 1.00 72.43  ? 300 LEU B CB  1 
ATOM   5276 C CG  . LEU B 1 300 ? 187.501 155.462 160.064 1.00 72.43  ? 300 LEU B CG  1 
ATOM   5277 C CD1 . LEU B 1 300 ? 187.336 156.827 159.433 1.00 72.43  ? 300 LEU B CD1 1 
ATOM   5278 C CD2 . LEU B 1 300 ? 188.713 155.433 160.976 1.00 72.43  ? 300 LEU B CD2 1 
ATOM   5279 N N   . PHE B 1 301 ? 184.087 153.039 162.382 1.00 70.69  ? 301 PHE B N   1 
ATOM   5280 C CA  . PHE B 1 301 ? 182.893 153.034 163.213 1.00 70.69  ? 301 PHE B CA  1 
ATOM   5281 C C   . PHE B 1 301 ? 182.910 151.928 164.256 1.00 70.69  ? 301 PHE B C   1 
ATOM   5282 O O   . PHE B 1 301 ? 181.870 151.635 164.853 1.00 70.69  ? 301 PHE B O   1 
ATOM   5283 C CB  . PHE B 1 301 ? 181.646 152.920 162.338 1.00 70.69  ? 301 PHE B CB  1 
ATOM   5284 C CG  . PHE B 1 301 ? 181.388 154.139 161.504 1.00 70.69  ? 301 PHE B CG  1 
ATOM   5285 C CD1 . PHE B 1 301 ? 181.105 155.353 162.104 1.00 70.69  ? 301 PHE B CD1 1 
ATOM   5286 C CD2 . PHE B 1 301 ? 181.446 154.076 160.124 1.00 70.69  ? 301 PHE B CD2 1 
ATOM   5287 C CE1 . PHE B 1 301 ? 180.877 156.477 161.345 1.00 70.69  ? 301 PHE B CE1 1 
ATOM   5288 C CE2 . PHE B 1 301 ? 181.218 155.198 159.359 1.00 70.69  ? 301 PHE B CE2 1 
ATOM   5289 C CZ  . PHE B 1 301 ? 180.934 156.400 159.971 1.00 70.69  ? 301 PHE B CZ  1 
ATOM   5290 N N   . ARG B 1 302 ? 184.062 151.298 164.480 1.00 77.92  ? 302 ARG B N   1 
ATOM   5291 C CA  . ARG B 1 302 ? 184.183 150.334 165.565 1.00 77.92  ? 302 ARG B CA  1 
ATOM   5292 C C   . ARG B 1 302 ? 184.280 151.017 166.922 1.00 77.92  ? 302 ARG B C   1 
ATOM   5293 O O   . ARG B 1 302 ? 183.843 150.449 167.929 1.00 77.92  ? 302 ARG B O   1 
ATOM   5294 C CB  . ARG B 1 302 ? 185.400 149.439 165.333 1.00 77.92  ? 302 ARG B CB  1 
ATOM   5295 C CG  . ARG B 1 302 ? 185.261 148.521 164.135 1.00 77.92  ? 302 ARG B CG  1 
ATOM   5296 C CD  . ARG B 1 302 ? 186.493 147.661 163.950 1.00 77.92  ? 302 ARG B CD  1 
ATOM   5297 N NE  . ARG B 1 302 ? 186.374 146.790 162.788 1.00 77.92  ? 302 ARG B NE  1 
ATOM   5298 C CZ  . ARG B 1 302 ? 187.328 145.974 162.362 1.00 77.92  ? 302 ARG B CZ  1 
ATOM   5299 N NH1 . ARG B 1 302 ? 188.494 145.892 162.982 1.00 77.92  ? 302 ARG B NH1 1 
ATOM   5300 N NH2 . ARG B 1 302 ? 187.108 145.222 161.288 1.00 77.92  ? 302 ARG B NH2 1 
ATOM   5301 N N   . ASP B 1 303 ? 184.840 152.223 166.968 1.00 72.82  ? 303 ASP B N   1 
ATOM   5302 C CA  . ASP B 1 303 ? 184.985 152.945 168.225 1.00 72.82  ? 303 ASP B CA  1 
ATOM   5303 C C   . ASP B 1 303 ? 183.622 153.341 168.778 1.00 72.82  ? 303 ASP B C   1 
ATOM   5304 O O   . ASP B 1 303 ? 182.740 153.787 168.041 1.00 72.82  ? 303 ASP B O   1 
ATOM   5305 C CB  . ASP B 1 303 ? 185.857 154.183 168.018 1.00 72.82  ? 303 ASP B CB  1 
ATOM   5306 C CG  . ASP B 1 303 ? 186.081 154.963 169.298 1.00 72.82  ? 303 ASP B CG  1 
ATOM   5307 O OD1 . ASP B 1 303 ? 186.474 154.351 170.313 1.00 72.82  ? 303 ASP B OD1 1 
ATOM   5308 O OD2 . ASP B 1 303 ? 185.872 156.194 169.286 1.00 72.82  ? 303 ASP B OD2 1 
ATOM   5309 N N   . ARG B 1 304 ? 183.451 153.168 170.091 1.00 72.18  ? 304 ARG B N   1 
ATOM   5310 C CA  . ARG B 1 304 ? 182.166 153.462 170.720 1.00 72.18  ? 304 ARG B CA  1 
ATOM   5311 C C   . ARG B 1 304 ? 181.864 154.956 170.686 1.00 72.18  ? 304 ARG B C   1 
ATOM   5312 O O   . ARG B 1 304 ? 180.714 155.361 170.461 1.00 72.18  ? 304 ARG B O   1 
ATOM   5313 C CB  . ARG B 1 304 ? 182.163 152.925 172.155 1.00 72.18  ? 304 ARG B CB  1 
ATOM   5314 C CG  . ARG B 1 304 ? 180.832 153.025 172.912 1.00 72.18  ? 304 ARG B CG  1 
ATOM   5315 C CD  . ARG B 1 304 ? 180.632 154.362 173.621 1.00 72.18  ? 304 ARG B CD  1 
ATOM   5316 N NE  . ARG B 1 304 ? 181.708 154.675 174.553 1.00 72.18  ? 304 ARG B NE  1 
ATOM   5317 C CZ  . ARG B 1 304 ? 181.787 154.206 175.790 1.00 72.18  ? 304 ARG B CZ  1 
ATOM   5318 N NH1 . ARG B 1 304 ? 180.865 153.395 176.282 1.00 72.18  ? 304 ARG B NH1 1 
ATOM   5319 N NH2 . ARG B 1 304 ? 182.813 154.565 176.556 1.00 72.18  ? 304 ARG B NH2 1 
ATOM   5320 N N   . ASN B 1 305 ? 182.886 155.788 170.904 1.00 67.03  ? 305 ASN B N   1 
ATOM   5321 C CA  . ASN B 1 305 ? 182.677 157.231 170.939 1.00 67.03  ? 305 ASN B CA  1 
ATOM   5322 C C   . ASN B 1 305 ? 182.144 157.746 169.610 1.00 67.03  ? 305 ASN B C   1 
ATOM   5323 O O   . ASN B 1 305 ? 181.217 158.562 169.584 1.00 67.03  ? 305 ASN B O   1 
ATOM   5324 C CB  . ASN B 1 305 ? 183.980 157.941 171.300 1.00 67.03  ? 305 ASN B CB  1 
ATOM   5325 C CG  . ASN B 1 305 ? 184.485 157.568 172.674 1.00 67.03  ? 305 ASN B CG  1 
ATOM   5326 O OD1 . ASN B 1 305 ? 183.829 156.833 173.409 1.00 67.03  ? 305 ASN B OD1 1 
ATOM   5327 N ND2 . ASN B 1 305 ? 185.659 158.071 173.031 1.00 67.03  ? 305 ASN B ND2 1 
ATOM   5328 N N   . ARG B 1 306 ? 182.711 157.279 168.495 1.00 63.90  ? 306 ARG B N   1 
ATOM   5329 C CA  . ARG B 1 306 ? 182.255 157.743 167.189 1.00 63.90  ? 306 ARG B CA  1 
ATOM   5330 C C   . ARG B 1 306 ? 180.817 157.319 166.918 1.00 63.90  ? 306 ARG B C   1 
ATOM   5331 O O   . ARG B 1 306 ? 180.025 158.106 166.386 1.00 63.90  ? 306 ARG B O   1 
ATOM   5332 C CB  . ARG B 1 306 ? 183.182 157.229 166.090 1.00 63.90  ? 306 ARG B CB  1 
ATOM   5333 C CG  . ARG B 1 306 ? 183.295 158.175 164.907 1.00 63.90  ? 306 ARG B CG  1 
ATOM   5334 C CD  . ARG B 1 306 ? 184.185 157.618 163.813 1.00 63.90  ? 306 ARG B CD  1 
ATOM   5335 N NE  . ARG B 1 306 ? 185.524 157.305 164.294 1.00 63.90  ? 306 ARG B NE  1 
ATOM   5336 C CZ  . ARG B 1 306 ? 186.524 158.174 164.336 1.00 63.90  ? 306 ARG B CZ  1 
ATOM   5337 N NH1 . ARG B 1 306 ? 186.366 159.428 163.948 1.00 63.90  ? 306 ARG B NH1 1 
ATOM   5338 N NH2 . ARG B 1 306 ? 187.712 157.776 164.780 1.00 63.90  ? 306 ARG B NH2 1 
ATOM   5339 N N   . LEU B 1 307 ? 180.457 156.086 167.277 1.00 62.61  ? 307 LEU B N   1 
ATOM   5340 C CA  . LEU B 1 307 ? 179.089 155.623 167.064 1.00 62.61  ? 307 LEU B CA  1 
ATOM   5341 C C   . LEU B 1 307 ? 178.096 156.455 167.864 1.00 62.61  ? 307 LEU B C   1 
ATOM   5342 O O   . LEU B 1 307 ? 177.068 156.901 167.334 1.00 62.61  ? 307 LEU B O   1 
ATOM   5343 C CB  . LEU B 1 307 ? 178.971 154.149 167.441 1.00 62.61  ? 307 LEU B CB  1 
ATOM   5344 C CG  . LEU B 1 307 ? 179.490 153.138 166.425 1.00 62.61  ? 307 LEU B CG  1 
ATOM   5345 C CD1 . LEU B 1 307 ? 179.385 151.735 166.987 1.00 62.61  ? 307 LEU B CD1 1 
ATOM   5346 C CD2 . LEU B 1 307 ? 178.718 153.258 165.125 1.00 62.61  ? 307 LEU B CD2 1 
ATOM   5347 N N   . VAL B 1 308 ? 178.390 156.678 169.147 1.00 61.69  ? 308 VAL B N   1 
ATOM   5348 C CA  . VAL B 1 308 ? 177.482 157.465 169.977 1.00 61.69  ? 308 VAL B CA  1 
ATOM   5349 C C   . VAL B 1 308 ? 177.389 158.894 169.458 1.00 61.69  ? 308 VAL B C   1 
ATOM   5350 O O   . VAL B 1 308 ? 176.300 159.481 169.402 1.00 61.69  ? 308 VAL B O   1 
ATOM   5351 C CB  . VAL B 1 308 ? 177.924 157.420 171.449 1.00 61.69  ? 308 VAL B CB  1 
ATOM   5352 C CG1 . VAL B 1 308 ? 177.006 158.271 172.299 1.00 61.69  ? 308 VAL B CG1 1 
ATOM   5353 C CG2 . VAL B 1 308 ? 177.923 155.992 171.946 1.00 61.69  ? 308 VAL B CG2 1 
ATOM   5354 N N   . THR B 1 309 ? 178.525 159.473 169.058 1.00 58.34  ? 309 THR B N   1 
ATOM   5355 C CA  . THR B 1 309 ? 178.525 160.843 168.561 1.00 58.34  ? 309 THR B CA  1 
ATOM   5356 C C   . THR B 1 309 ? 177.704 160.973 167.286 1.00 58.34  ? 309 THR B C   1 
ATOM   5357 O O   . THR B 1 309 ? 176.954 161.939 167.122 1.00 58.34  ? 309 THR B O   1 
ATOM   5358 C CB  . THR B 1 309 ? 179.957 161.312 168.319 1.00 58.34  ? 309 THR B CB  1 
ATOM   5359 O OG1 . THR B 1 309 ? 180.754 161.023 169.472 1.00 58.34  ? 309 THR B OG1 1 
ATOM   5360 C CG2 . THR B 1 309 ? 179.986 162.803 168.058 1.00 58.34  ? 309 THR B CG2 1 
ATOM   5361 N N   . PHE B 1 310 ? 177.823 160.009 166.372 1.00 57.04  ? 310 PHE B N   1 
ATOM   5362 C CA  . PHE B 1 310 ? 177.089 160.112 165.117 1.00 57.04  ? 310 PHE B CA  1 
ATOM   5363 C C   . PHE B 1 310 ? 175.596 159.885 165.326 1.00 57.04  ? 310 PHE B C   1 
ATOM   5364 O O   . PHE B 1 310 ? 174.767 160.545 164.685 1.00 57.04  ? 310 PHE B O   1 
ATOM   5365 C CB  . PHE B 1 310 ? 177.666 159.138 164.094 1.00 57.04  ? 310 PHE B CB  1 
ATOM   5366 C CG  . PHE B 1 310 ? 178.839 159.694 163.335 1.00 57.04  ? 310 PHE B CG  1 
ATOM   5367 C CD1 . PHE B 1 310 ? 179.875 160.323 164.002 1.00 57.04  ? 310 PHE B CD1 1 
ATOM   5368 C CD2 . PHE B 1 310 ? 178.901 159.603 161.958 1.00 57.04  ? 310 PHE B CD2 1 
ATOM   5369 C CE1 . PHE B 1 310 ? 180.949 160.841 163.314 1.00 57.04  ? 310 PHE B CE1 1 
ATOM   5370 C CE2 . PHE B 1 310 ? 179.976 160.121 161.266 1.00 57.04  ? 310 PHE B CE2 1 
ATOM   5371 C CZ  . PHE B 1 310 ? 180.999 160.741 161.946 1.00 57.04  ? 310 PHE B CZ  1 
ATOM   5372 N N   . SER B 1 311 ? 175.230 158.976 166.234 1.00 56.69  ? 311 SER B N   1 
ATOM   5373 C CA  . SER B 1 311 ? 173.817 158.810 166.566 1.00 56.69  ? 311 SER B CA  1 
ATOM   5374 C C   . SER B 1 311 ? 173.242 160.085 167.174 1.00 56.69  ? 311 SER B C   1 
ATOM   5375 O O   . SER B 1 311 ? 172.128 160.510 166.828 1.00 56.69  ? 311 SER B O   1 
ATOM   5376 C CB  . SER B 1 311 ? 173.648 157.633 167.523 1.00 56.69  ? 311 SER B CB  1 
ATOM   5377 O OG  . SER B 1 311 ? 174.057 156.423 166.913 1.00 56.69  ? 311 SER B OG  1 
ATOM   5378 N N   . ALA B 1 312 ? 173.998 160.716 168.079 1.00 57.39  ? 312 ALA B N   1 
ATOM   5379 C CA  . ALA B 1 312 ? 173.555 161.972 168.671 1.00 57.39  ? 312 ALA B CA  1 
ATOM   5380 C C   . ALA B 1 312 ? 173.429 163.063 167.618 1.00 57.39  ? 312 ALA B C   1 
ATOM   5381 O O   . ALA B 1 312 ? 172.497 163.870 167.664 1.00 57.39  ? 312 ALA B O   1 
ATOM   5382 C CB  . ALA B 1 312 ? 174.518 162.399 169.777 1.00 57.39  ? 312 ALA B CB  1 
ATOM   5383 N N   . ILE B 1 313 ? 174.361 163.106 166.664 1.00 56.65  ? 313 ILE B N   1 
ATOM   5384 C CA  . ILE B 1 313 ? 174.292 164.091 165.586 1.00 56.65  ? 313 ILE B CA  1 
ATOM   5385 C C   . ILE B 1 313 ? 173.012 163.906 164.783 1.00 56.65  ? 313 ILE B C   1 
ATOM   5386 O O   . ILE B 1 313 ? 172.289 164.870 164.499 1.00 56.65  ? 313 ILE B O   1 
ATOM   5387 C CB  . ILE B 1 313 ? 175.538 163.984 164.688 1.00 56.65  ? 313 ILE B CB  1 
ATOM   5388 C CG1 . ILE B 1 313 ? 176.736 164.663 165.351 1.00 56.65  ? 313 ILE B CG1 1 
ATOM   5389 C CG2 . ILE B 1 313 ? 175.270 164.579 163.319 1.00 56.65  ? 313 ILE B CG2 1 
ATOM   5390 C CD1 . ILE B 1 313 ? 178.058 164.282 164.739 1.00 56.65  ? 313 ILE B CD1 1 
ATOM   5391 N N   . LEU B 1 314 ? 172.707 162.659 164.420 1.00 55.88  ? 314 LEU B N   1 
ATOM   5392 C CA  . LEU B 1 314 ? 171.486 162.371 163.671 1.00 55.88  ? 314 LEU B CA  1 
ATOM   5393 C C   . LEU B 1 314 ? 170.248 162.855 164.420 1.00 55.88  ? 314 LEU B C   1 
ATOM   5394 O O   . LEU B 1 314 ? 169.425 163.612 163.878 1.00 55.88  ? 314 LEU B O   1 
ATOM   5395 C CB  . LEU B 1 314 ? 171.401 160.868 163.403 1.00 55.88  ? 314 LEU B CB  1 
ATOM   5396 C CG  . LEU B 1 314 ? 170.141 160.263 162.787 1.00 55.88  ? 314 LEU B CG  1 
ATOM   5397 C CD1 . LEU B 1 314 ? 170.119 160.464 161.289 1.00 55.88  ? 314 LEU B CD1 1 
ATOM   5398 C CD2 . LEU B 1 314 ? 170.064 158.788 163.123 1.00 55.88  ? 314 LEU B CD2 1 
ATOM   5399 N N   . LEU B 1 315 ? 170.114 162.452 165.684 1.00 57.30  ? 315 LEU B N   1 
ATOM   5400 C CA  . LEU B 1 315 ? 168.879 162.751 166.401 1.00 57.30  ? 315 LEU B CA  1 
ATOM   5401 C C   . LEU B 1 315 ? 168.772 164.240 166.733 1.00 57.30  ? 315 LEU B C   1 
ATOM   5402 O O   . LEU B 1 315 ? 167.673 164.811 166.708 1.00 57.30  ? 315 LEU B O   1 
ATOM   5403 C CB  . LEU B 1 315 ? 168.788 161.885 167.656 1.00 57.30  ? 315 LEU B CB  1 
ATOM   5404 C CG  . LEU B 1 315 ? 167.421 161.796 168.328 1.00 57.30  ? 315 LEU B CG  1 
ATOM   5405 C CD1 . LEU B 1 315 ? 166.399 161.254 167.352 1.00 57.30  ? 315 LEU B CD1 1 
ATOM   5406 C CD2 . LEU B 1 315 ? 167.505 160.901 169.543 1.00 57.30  ? 315 LEU B CD2 1 
ATOM   5407 N N   . ALA B 1 316 ? 169.901 164.894 167.020 1.00 57.04  ? 316 ALA B N   1 
ATOM   5408 C CA  . ALA B 1 316 ? 169.890 166.327 167.291 1.00 57.04  ? 316 ALA B CA  1 
ATOM   5409 C C   . ALA B 1 316 ? 169.536 167.129 166.046 1.00 57.04  ? 316 ALA B C   1 
ATOM   5410 O O   . ALA B 1 316 ? 168.809 168.126 166.132 1.00 57.04  ? 316 ALA B O   1 
ATOM   5411 C CB  . ALA B 1 316 ? 171.245 166.766 167.841 1.00 57.04  ? 316 ALA B CB  1 
ATOM   5412 N N   . GLY B 1 317 ? 170.054 166.728 164.882 1.00 56.91  ? 317 GLY B N   1 
ATOM   5413 C CA  . GLY B 1 317 ? 169.643 167.378 163.651 1.00 56.91  ? 317 GLY B CA  1 
ATOM   5414 C C   . GLY B 1 317 ? 168.156 167.233 163.402 1.00 56.91  ? 317 GLY B C   1 
ATOM   5415 O O   . GLY B 1 317 ? 167.489 168.184 162.979 1.00 56.91  ? 317 GLY B O   1 
ATOM   5416 N N   . GLY B 1 318 ? 167.614 166.045 163.677 1.00 57.59  ? 318 GLY B N   1 
ATOM   5417 C CA  . GLY B 1 318 ? 166.172 165.869 163.569 1.00 57.59  ? 318 GLY B CA  1 
ATOM   5418 C C   . GLY B 1 318 ? 165.399 166.803 164.482 1.00 57.59  ? 318 GLY B C   1 
ATOM   5419 O O   . GLY B 1 318 ? 164.413 167.425 164.071 1.00 57.59  ? 318 GLY B O   1 
ATOM   5420 N N   . VAL B 1 319 ? 165.845 166.920 165.735 1.00 58.01  ? 319 VAL B N   1 
ATOM   5421 C CA  . VAL B 1 319 ? 165.159 167.784 166.696 1.00 58.01  ? 319 VAL B CA  1 
ATOM   5422 C C   . VAL B 1 319 ? 165.197 169.238 166.238 1.00 58.01  ? 319 VAL B C   1 
ATOM   5423 O O   . VAL B 1 319 ? 164.189 169.955 166.308 1.00 58.01  ? 319 VAL B O   1 
ATOM   5424 C CB  . VAL B 1 319 ? 165.774 167.615 168.097 1.00 58.01  ? 319 VAL B CB  1 
ATOM   5425 C CG1 . VAL B 1 319 ? 165.351 168.753 169.010 1.00 58.01  ? 319 VAL B CG1 1 
ATOM   5426 C CG2 . VAL B 1 319 ? 165.371 166.280 168.692 1.00 58.01  ? 319 VAL B CG2 1 
ATOM   5427 N N   . MET B 1 320 ? 166.359 169.698 165.771 1.00 60.69  ? 320 MET B N   1 
ATOM   5428 C CA  . MET B 1 320 ? 166.479 171.087 165.335 1.00 60.69  ? 320 MET B CA  1 
ATOM   5429 C C   . MET B 1 320 ? 165.600 171.371 164.122 1.00 60.69  ? 320 MET B C   1 
ATOM   5430 O O   . MET B 1 320 ? 164.949 172.423 164.050 1.00 60.69  ? 320 MET B O   1 
ATOM   5431 C CB  . MET B 1 320 ? 167.939 171.415 165.031 1.00 60.69  ? 320 MET B CB  1 
ATOM   5432 C CG  . MET B 1 320 ? 168.167 172.841 164.575 1.00 60.69  ? 320 MET B CG  1 
ATOM   5433 S SD  . MET B 1 320 ? 168.417 173.982 165.946 1.00 60.69  ? 320 MET B SD  1 
ATOM   5434 C CE  . MET B 1 320 ? 167.176 175.221 165.585 1.00 60.69  ? 320 MET B CE  1 
ATOM   5435 N N   . PHE B 1 321 ? 165.567 170.448 163.156 1.00 59.26  ? 321 PHE B N   1 
ATOM   5436 C CA  . PHE B 1 321 ? 164.708 170.640 161.990 1.00 59.26  ? 321 PHE B CA  1 
ATOM   5437 C C   . PHE B 1 321 ? 163.239 170.698 162.390 1.00 59.26  ? 321 PHE B C   1 
ATOM   5438 O O   . PHE B 1 321 ? 162.478 171.537 161.884 1.00 59.26  ? 321 PHE B O   1 
ATOM   5439 C CB  . PHE B 1 321 ? 164.945 169.520 160.980 1.00 59.26  ? 321 PHE B CB  1 
ATOM   5440 C CG  . PHE B 1 321 ? 164.336 169.776 159.632 1.00 59.26  ? 321 PHE B CG  1 
ATOM   5441 C CD1 . PHE B 1 321 ? 164.882 170.716 158.777 1.00 59.26  ? 321 PHE B CD1 1 
ATOM   5442 C CD2 . PHE B 1 321 ? 163.225 169.067 159.215 1.00 59.26  ? 321 PHE B CD2 1 
ATOM   5443 C CE1 . PHE B 1 321 ? 164.326 170.946 157.537 1.00 59.26  ? 321 PHE B CE1 1 
ATOM   5444 C CE2 . PHE B 1 321 ? 162.666 169.293 157.977 1.00 59.26  ? 321 PHE B CE2 1 
ATOM   5445 C CZ  . PHE B 1 321 ? 163.216 170.233 157.137 1.00 59.26  ? 321 PHE B CZ  1 
ATOM   5446 N N   . SER B 1 322 ? 162.821 169.810 163.298 1.00 58.77  ? 322 SER B N   1 
ATOM   5447 C CA  . SER B 1 322 ? 161.436 169.822 163.756 1.00 58.77  ? 322 SER B CA  1 
ATOM   5448 C C   . SER B 1 322 ? 161.095 171.144 164.430 1.00 58.77  ? 322 SER B C   1 
ATOM   5449 O O   . SER B 1 322 ? 160.043 171.737 164.160 1.00 58.77  ? 322 SER B O   1 
ATOM   5450 C CB  . SER B 1 322 ? 161.190 168.654 164.708 1.00 58.77  ? 322 SER B CB  1 
ATOM   5451 O OG  . SER B 1 322 ? 161.763 167.463 164.203 1.00 58.77  ? 322 SER B OG  1 
ATOM   5452 N N   . LEU B 1 323 ? 161.979 171.626 165.309 1.00 57.95  ? 323 LEU B N   1 
ATOM   5453 C CA  . LEU B 1 323 ? 161.749 172.915 165.956 1.00 57.95  ? 323 LEU B CA  1 
ATOM   5454 C C   . LEU B 1 323 ? 161.583 174.023 164.929 1.00 57.95  ? 323 LEU B C   1 
ATOM   5455 O O   . LEU B 1 323 ? 160.616 174.791 164.980 1.00 57.95  ? 323 LEU B O   1 
ATOM   5456 C CB  . LEU B 1 323 ? 162.896 173.255 166.908 1.00 57.95  ? 323 LEU B CB  1 
ATOM   5457 C CG  . LEU B 1 323 ? 162.960 172.576 168.270 1.00 57.95  ? 323 LEU B CG  1 
ATOM   5458 C CD1 . LEU B 1 323 ? 164.273 172.912 168.946 1.00 57.95  ? 323 LEU B CD1 1 
ATOM   5459 C CD2 . LEU B 1 323 ? 161.795 173.037 169.122 1.00 57.95  ? 323 LEU B CD2 1 
ATOM   5460 N N   . THR B 1 324 ? 162.517 174.116 163.980 1.00 59.17  ? 324 THR B N   1 
ATOM   5461 C CA  . THR B 1 324 ? 162.461 175.191 162.994 1.00 59.17  ? 324 THR B CA  1 
ATOM   5462 C C   . THR B 1 324 ? 161.143 175.170 162.229 1.00 59.17  ? 324 THR B C   1 
ATOM   5463 O O   . THR B 1 324 ? 160.419 176.175 162.185 1.00 59.17  ? 324 THR B O   1 
ATOM   5464 C CB  . THR B 1 324 ? 163.640 175.076 162.029 1.00 59.17  ? 324 THR B CB  1 
ATOM   5465 O OG1 . THR B 1 324 ? 164.868 175.144 162.762 1.00 59.17  ? 324 THR B OG1 1 
ATOM   5466 C CG2 . THR B 1 324 ? 163.603 176.195 161.008 1.00 59.17  ? 324 THR B CG2 1 
ATOM   5467 N N   . VAL B 1 325 ? 160.797 174.016 161.651 1.00 60.47  ? 325 VAL B N   1 
ATOM   5468 C CA  . VAL B 1 325 ? 159.617 173.949 160.790 1.00 60.47  ? 325 VAL B CA  1 
ATOM   5469 C C   . VAL B 1 325 ? 158.348 174.207 161.595 1.00 60.47  ? 325 VAL B C   1 
ATOM   5470 O O   . VAL B 1 325 ? 157.486 175.001 161.192 1.00 60.47  ? 325 VAL B O   1 
ATOM   5471 C CB  . VAL B 1 325 ? 159.559 172.595 160.062 1.00 60.47  ? 325 VAL B CB  1 
ATOM   5472 C CG1 . VAL B 1 325 ? 158.230 172.435 159.349 1.00 60.47  ? 325 VAL B CG1 1 
ATOM   5473 C CG2 . VAL B 1 325 ? 160.706 172.481 159.079 1.00 60.47  ? 325 VAL B CG2 1 
ATOM   5474 N N   . CYS B 1 326 ? 158.214 173.545 162.749 1.00 63.51  ? 326 CYS B N   1 
ATOM   5475 C CA  . CYS B 1 326 ? 156.988 173.673 163.527 1.00 63.51  ? 326 CYS B CA  1 
ATOM   5476 C C   . CYS B 1 326 ? 156.806 175.087 164.060 1.00 63.51  ? 326 CYS B C   1 
ATOM   5477 O O   . CYS B 1 326 ? 155.692 175.622 164.031 1.00 63.51  ? 326 CYS B O   1 
ATOM   5478 C CB  . CYS B 1 326 ? 156.988 172.660 164.670 1.00 63.51  ? 326 CYS B CB  1 
ATOM   5479 S SG  . CYS B 1 326 ? 156.795 170.948 164.130 1.00 63.51  ? 326 CYS B SG  1 
ATOM   5480 N N   . ILE B 1 327 ? 157.878 175.717 164.546 1.00 62.96  ? 327 ILE B N   1 
ATOM   5481 C CA  . ILE B 1 327 ? 157.745 177.064 165.089 1.00 62.96  ? 327 ILE B CA  1 
ATOM   5482 C C   . ILE B 1 327 ? 157.435 178.061 163.981 1.00 62.96  ? 327 ILE B C   1 
ATOM   5483 O O   . ILE B 1 327 ? 156.618 178.972 164.165 1.00 62.96  ? 327 ILE B O   1 
ATOM   5484 C CB  . ILE B 1 327 ? 159.009 177.450 165.876 1.00 62.96  ? 327 ILE B CB  1 
ATOM   5485 C CG1 . ILE B 1 327 ? 159.061 176.666 167.187 1.00 62.96  ? 327 ILE B CG1 1 
ATOM   5486 C CG2 . ILE B 1 327 ? 159.032 178.941 166.159 1.00 62.96  ? 327 ILE B CG2 1 
ATOM   5487 C CD1 . ILE B 1 327 ? 160.211 177.041 168.078 1.00 62.96  ? 327 ILE B CD1 1 
ATOM   5488 N N   . GLY B 1 328 ? 158.061 177.906 162.810 1.00 61.10  ? 328 GLY B N   1 
ATOM   5489 C CA  . GLY B 1 328 ? 157.720 178.780 161.699 1.00 61.10  ? 328 GLY B CA  1 
ATOM   5490 C C   . GLY B 1 328 ? 156.263 178.660 161.296 1.00 61.10  ? 328 GLY B C   1 
ATOM   5491 O O   . GLY B 1 328 ? 155.571 179.665 161.096 1.00 61.10  ? 328 GLY B O   1 
ATOM   5492 N N   . LEU B 1 329 ? 155.771 177.421 161.185 1.00 64.08  ? 329 LEU B N   1 
ATOM   5493 C CA  . LEU B 1 329 ? 154.375 177.213 160.814 1.00 64.08  ? 329 LEU B CA  1 
ATOM   5494 C C   . LEU B 1 329 ? 153.429 177.775 161.868 1.00 64.08  ? 329 LEU B C   1 
ATOM   5495 O O   . LEU B 1 329 ? 152.406 178.380 161.531 1.00 64.08  ? 329 LEU B O   1 
ATOM   5496 C CB  . LEU B 1 329 ? 154.103 175.726 160.593 1.00 64.08  ? 329 LEU B CB  1 
ATOM   5497 C CG  . LEU B 1 329 ? 154.434 175.174 159.208 1.00 64.08  ? 329 LEU B CG  1 
ATOM   5498 C CD1 . LEU B 1 329 ? 153.886 173.768 159.054 1.00 64.08  ? 329 LEU B CD1 1 
ATOM   5499 C CD2 . LEU B 1 329 ? 153.891 176.086 158.126 1.00 64.08  ? 329 LEU B CD2 1 
ATOM   5500 N N   . TYR B 1 330 ? 153.749 177.578 163.149 1.00 64.64  ? 330 TYR B N   1 
ATOM   5501 C CA  . TYR B 1 330 ? 152.898 178.103 164.210 1.00 64.64  ? 330 TYR B CA  1 
ATOM   5502 C C   . TYR B 1 330 ? 152.846 179.622 164.179 1.00 64.64  ? 330 TYR B C   1 
ATOM   5503 O O   . TYR B 1 330 ? 151.770 180.216 164.303 1.00 64.64  ? 330 TYR B O   1 
ATOM   5504 C CB  . TYR B 1 330 ? 153.395 177.617 165.570 1.00 64.64  ? 330 TYR B CB  1 
ATOM   5505 C CG  . TYR B 1 330 ? 152.596 178.141 166.741 1.00 64.64  ? 330 TYR B CG  1 
ATOM   5506 C CD1 . TYR B 1 330 ? 151.456 177.484 167.175 1.00 64.64  ? 330 TYR B CD1 1 
ATOM   5507 C CD2 . TYR B 1 330 ? 152.985 179.289 167.415 1.00 64.64  ? 330 TYR B CD2 1 
ATOM   5508 C CE1 . TYR B 1 330 ? 150.725 177.956 168.242 1.00 64.64  ? 330 TYR B CE1 1 
ATOM   5509 C CE2 . TYR B 1 330 ? 152.258 179.769 168.482 1.00 64.64  ? 330 TYR B CE2 1 
ATOM   5510 C CZ  . TYR B 1 330 ? 151.130 179.097 168.891 1.00 64.64  ? 330 TYR B CZ  1 
ATOM   5511 O OH  . TYR B 1 330 ? 150.403 179.570 169.955 1.00 64.64  ? 330 TYR B OH  1 
ATOM   5512 N N   . VAL B 1 331 ? 154.001 180.270 164.020 1.00 65.00  ? 331 VAL B N   1 
ATOM   5513 C CA  . VAL B 1 331 ? 154.037 181.728 164.024 1.00 65.00  ? 331 VAL B CA  1 
ATOM   5514 C C   . VAL B 1 331 ? 153.278 182.289 162.829 1.00 65.00  ? 331 VAL B C   1 
ATOM   5515 O O   . VAL B 1 331 ? 152.490 183.231 162.967 1.00 65.00  ? 331 VAL B O   1 
ATOM   5516 C CB  . VAL B 1 331 ? 155.494 182.223 164.059 1.00 65.00  ? 331 VAL B CB  1 
ATOM   5517 C CG1 . VAL B 1 331 ? 155.589 183.644 163.543 1.00 65.00  ? 331 VAL B CG1 1 
ATOM   5518 C CG2 . VAL B 1 331 ? 156.044 182.134 165.469 1.00 65.00  ? 331 VAL B CG2 1 
ATOM   5519 N N   . GLN B 1 332 ? 153.486 181.719 161.641 1.00 68.93  ? 332 GLN B N   1 
ATOM   5520 C CA  . GLN B 1 332 ? 152.855 182.280 160.452 1.00 68.93  ? 332 GLN B CA  1 
ATOM   5521 C C   . GLN B 1 332 ? 151.375 181.928 160.341 1.00 68.93  ? 332 GLN B C   1 
ATOM   5522 O O   . GLN B 1 332 ? 150.613 182.683 159.729 1.00 68.93  ? 332 GLN B O   1 
ATOM   5523 C CB  . GLN B 1 332 ? 153.597 181.821 159.199 1.00 68.93  ? 332 GLN B CB  1 
ATOM   5524 C CG  . GLN B 1 332 ? 154.868 182.601 158.929 1.00 68.93  ? 332 GLN B CG  1 
ATOM   5525 C CD  . GLN B 1 332 ? 155.575 182.140 157.678 1.00 68.93  ? 332 GLN B CD  1 
ATOM   5526 O OE1 . GLN B 1 332 ? 156.764 181.827 157.703 1.00 68.93  ? 332 GLN B OE1 1 
ATOM   5527 N NE2 . GLN B 1 332 ? 154.846 182.098 156.569 1.00 68.93  ? 332 GLN B NE2 1 
ATOM   5528 N N   . ASP B 1 333 ? 150.945 180.804 160.913 1.00 71.43  ? 333 ASP B N   1 
ATOM   5529 C CA  . ASP B 1 333 ? 149.572 180.334 160.770 1.00 71.43  ? 333 ASP B CA  1 
ATOM   5530 C C   . ASP B 1 333 ? 148.672 180.759 161.923 1.00 71.43  ? 333 ASP B C   1 
ATOM   5531 O O   . ASP B 1 333 ? 147.616 181.354 161.697 1.00 71.43  ? 333 ASP B O   1 
ATOM   5532 C CB  . ASP B 1 333 ? 149.553 178.808 160.638 1.00 71.43  ? 333 ASP B CB  1 
ATOM   5533 C CG  . ASP B 1 333 ? 149.910 178.339 159.244 1.00 71.43  ? 333 ASP B CG  1 
ATOM   5534 O OD1 . ASP B 1 333 ? 150.476 179.141 158.473 1.00 71.43  ? 333 ASP B OD1 1 
ATOM   5535 O OD2 . ASP B 1 333 ? 149.625 177.167 158.919 1.00 71.43  ? 333 ASP B OD2 1 
ATOM   5536 N N   . ILE B 1 334 ? 149.063 180.456 163.159 1.00 69.24  ? 334 ILE B N   1 
ATOM   5537 C CA  . ILE B 1 334 ? 148.207 180.744 164.307 1.00 69.24  ? 334 ILE B CA  1 
ATOM   5538 C C   . ILE B 1 334 ? 148.286 182.217 164.685 1.00 69.24  ? 334 ILE B C   1 
ATOM   5539 O O   . ILE B 1 334 ? 147.267 182.913 164.755 1.00 69.24  ? 334 ILE B O   1 
ATOM   5540 C CB  . ILE B 1 334 ? 148.580 179.841 165.495 1.00 69.24  ? 334 ILE B CB  1 
ATOM   5541 C CG1 . ILE B 1 334 ? 148.433 178.369 165.112 1.00 69.24  ? 334 ILE B CG1 1 
ATOM   5542 C CG2 . ILE B 1 334 ? 147.719 180.169 166.697 1.00 69.24  ? 334 ILE B CG2 1 
ATOM   5543 C CD1 . ILE B 1 334 ? 147.044 177.993 164.668 1.00 69.24  ? 334 ILE B CD1 1 
ATOM   5544 N N   . LEU B 1 335 ? 149.499 182.716 164.933 1.00 68.39  ? 335 LEU B N   1 
ATOM   5545 C CA  . LEU B 1 335 ? 149.662 184.100 165.360 1.00 68.39  ? 335 LEU B CA  1 
ATOM   5546 C C   . LEU B 1 335 ? 149.333 185.098 164.258 1.00 68.39  ? 335 LEU B C   1 
ATOM   5547 O O   . LEU B 1 335 ? 149.046 186.260 164.561 1.00 68.39  ? 335 LEU B O   1 
ATOM   5548 C CB  . LEU B 1 335 ? 151.087 184.332 165.859 1.00 68.39  ? 335 LEU B CB  1 
ATOM   5549 C CG  . LEU B 1 335 ? 151.480 183.581 167.130 1.00 68.39  ? 335 LEU B CG  1 
ATOM   5550 C CD1 . LEU B 1 335 ? 152.867 183.988 167.582 1.00 68.39  ? 335 LEU B CD1 1 
ATOM   5551 C CD2 . LEU B 1 335 ? 150.466 183.827 168.227 1.00 68.39  ? 335 LEU B CD2 1 
ATOM   5552 N N   . GLY B 1 336 ? 149.367 184.680 162.997 1.00 68.90  ? 336 GLY B N   1 
ATOM   5553 C CA  . GLY B 1 336 ? 149.022 185.556 161.899 1.00 68.90  ? 336 GLY B CA  1 
ATOM   5554 C C   . GLY B 1 336 ? 150.138 186.434 161.382 1.00 68.90  ? 336 GLY B C   1 
ATOM   5555 O O   . GLY B 1 336 ? 149.877 187.303 160.543 1.00 68.90  ? 336 GLY B O   1 
ATOM   5556 N N   . TYR B 1 337 ? 151.367 186.244 161.853 1.00 69.43  ? 337 TYR B N   1 
ATOM   5557 C CA  . TYR B 1 337 ? 152.489 187.028 161.358 1.00 69.43  ? 337 TYR B CA  1 
ATOM   5558 C C   . TYR B 1 337 ? 152.745 186.716 159.889 1.00 69.43  ? 337 TYR B C   1 
ATOM   5559 O O   . TYR B 1 337 ? 152.579 185.579 159.441 1.00 69.43  ? 337 TYR B O   1 
ATOM   5560 C CB  . TYR B 1 337 ? 153.750 186.732 162.169 1.00 69.43  ? 337 TYR B CB  1 
ATOM   5561 C CG  . TYR B 1 337 ? 153.756 187.288 163.576 1.00 69.43  ? 337 TYR B CG  1 
ATOM   5562 C CD1 . TYR B 1 337 ? 152.638 187.914 164.107 1.00 69.43  ? 337 TYR B CD1 1 
ATOM   5563 C CD2 . TYR B 1 337 ? 154.887 187.182 164.374 1.00 69.43  ? 337 TYR B CD2 1 
ATOM   5564 C CE1 . TYR B 1 337 ? 152.646 188.417 165.391 1.00 69.43  ? 337 TYR B CE1 1 
ATOM   5565 C CE2 . TYR B 1 337 ? 154.904 187.683 165.658 1.00 69.43  ? 337 TYR B CE2 1 
ATOM   5566 C CZ  . TYR B 1 337 ? 153.781 188.299 166.162 1.00 69.43  ? 337 TYR B CZ  1 
ATOM   5567 O OH  . TYR B 1 337 ? 153.792 188.801 167.442 1.00 69.43  ? 337 TYR B OH  1 
ATOM   5568 N N   . SER B 1 338 ? 153.147 187.735 159.136 1.00 69.35  ? 338 SER B N   1 
ATOM   5569 C CA  . SER B 1 338 ? 153.561 187.527 157.759 1.00 69.35  ? 338 SER B CA  1 
ATOM   5570 C C   . SER B 1 338 ? 155.004 187.030 157.725 1.00 69.35  ? 338 SER B C   1 
ATOM   5571 O O   . SER B 1 338 ? 155.669 186.903 158.757 1.00 69.35  ? 338 SER B O   1 
ATOM   5572 C CB  . SER B 1 338 ? 153.389 188.812 156.954 1.00 69.35  ? 338 SER B CB  1 
ATOM   5573 O OG  . SER B 1 338 ? 154.126 189.875 157.526 1.00 69.35  ? 338 SER B OG  1 
ATOM   5574 N N   . ALA B 1 339 ? 155.497 186.728 156.523 1.00 68.13  ? 339 ALA B N   1 
ATOM   5575 C CA  . ALA B 1 339 ? 156.859 186.217 156.396 1.00 68.13  ? 339 ALA B CA  1 
ATOM   5576 C C   . ALA B 1 339 ? 157.885 187.256 156.827 1.00 68.13  ? 339 ALA B C   1 
ATOM   5577 O O   . ALA B 1 339 ? 158.854 186.930 157.524 1.00 68.13  ? 339 ALA B O   1 
ATOM   5578 C CB  . ALA B 1 339 ? 157.120 185.767 154.960 1.00 68.13  ? 339 ALA B CB  1 
ATOM   5579 N N   . LEU B 1 340 ? 157.690 188.513 156.426 1.00 67.39  ? 340 LEU B N   1 
ATOM   5580 C CA  . LEU B 1 340 ? 158.638 189.561 156.789 1.00 67.39  ? 340 LEU B CA  1 
ATOM   5581 C C   . LEU B 1 340 ? 158.657 189.798 158.294 1.00 67.39  ? 340 LEU B C   1 
ATOM   5582 O O   . LEU B 1 340 ? 159.727 189.985 158.885 1.00 67.39  ? 340 LEU B O   1 
ATOM   5583 C CB  . LEU B 1 340 ? 158.301 190.851 156.044 1.00 67.39  ? 340 LEU B CB  1 
ATOM   5584 C CG  . LEU B 1 340 ? 159.270 192.019 156.233 1.00 67.39  ? 340 LEU B CG  1 
ATOM   5585 C CD1 . LEU B 1 340 ? 160.680 191.616 155.844 1.00 67.39  ? 340 LEU B CD1 1 
ATOM   5586 C CD2 . LEU B 1 340 ? 158.813 193.217 155.422 1.00 67.39  ? 340 LEU B CD2 1 
ATOM   5587 N N   . ARG B 1 341 ? 157.483 189.793 158.932 1.00 69.28  ? 341 ARG B N   1 
ATOM   5588 C CA  . ARG B 1 341 ? 157.425 190.002 160.375 1.00 69.28  ? 341 ARG B CA  1 
ATOM   5589 C C   . ARG B 1 341 ? 158.137 188.887 161.128 1.00 69.28  ? 341 ARG B C   1 
ATOM   5590 O O   . ARG B 1 341 ? 158.882 189.149 162.078 1.00 69.28  ? 341 ARG B O   1 
ATOM   5591 C CB  . ARG B 1 341 ? 155.973 190.114 160.830 1.00 69.28  ? 341 ARG B CB  1 
ATOM   5592 C CG  . ARG B 1 341 ? 155.383 191.499 160.658 1.00 69.28  ? 341 ARG B CG  1 
ATOM   5593 C CD  . ARG B 1 341 ? 153.915 191.526 161.044 1.00 69.28  ? 341 ARG B CD  1 
ATOM   5594 N NE  . ARG B 1 341 ? 153.721 191.285 162.469 1.00 69.28  ? 341 ARG B NE  1 
ATOM   5595 C CZ  . ARG B 1 341 ? 153.705 192.235 163.393 1.00 69.28  ? 341 ARG B CZ  1 
ATOM   5596 N NH1 . ARG B 1 341 ? 153.872 193.508 163.078 1.00 69.28  ? 341 ARG B NH1 1 
ATOM   5597 N NH2 . ARG B 1 341 ? 153.518 191.898 164.666 1.00 69.28  ? 341 ARG B NH2 1 
ATOM   5598 N N   . ALA B 1 342 ? 157.925 187.634 160.718 1.00 65.12  ? 342 ALA B N   1 
ATOM   5599 C CA  . ALA B 1 342 ? 158.612 186.520 161.363 1.00 65.12  ? 342 ALA B CA  1 
ATOM   5600 C C   . ALA B 1 342 ? 160.118 186.588 161.133 1.00 65.12  ? 342 ALA B C   1 
ATOM   5601 O O   . ALA B 1 342 ? 160.907 186.330 162.053 1.00 65.12  ? 342 ALA B O   1 
ATOM   5602 C CB  . ALA B 1 342 ? 158.048 185.195 160.855 1.00 65.12  ? 342 ALA B CB  1 
ATOM   5603 N N   . GLY B 1 343 ? 160.535 186.931 159.914 1.00 64.41  ? 343 GLY B N   1 
ATOM   5604 C CA  . GLY B 1 343 ? 161.956 187.056 159.641 1.00 64.41  ? 343 GLY B CA  1 
ATOM   5605 C C   . GLY B 1 343 ? 162.614 188.142 160.467 1.00 64.41  ? 343 GLY B C   1 
ATOM   5606 O O   . GLY B 1 343 ? 163.755 187.994 160.908 1.00 64.41  ? 343 GLY B O   1 
ATOM   5607 N N   . VAL B 1 344 ? 161.907 189.252 160.682 1.00 63.52  ? 344 VAL B N   1 
ATOM   5608 C CA  . VAL B 1 344 ? 162.440 190.316 161.526 1.00 63.52  ? 344 VAL B CA  1 
ATOM   5609 C C   . VAL B 1 344 ? 162.466 189.880 162.986 1.00 63.52  ? 344 VAL B C   1 
ATOM   5610 O O   . VAL B 1 344 ? 163.417 190.175 163.718 1.00 63.52  ? 344 VAL B O   1 
ATOM   5611 C CB  . VAL B 1 344 ? 161.627 191.608 161.328 1.00 63.52  ? 344 VAL B CB  1 
ATOM   5612 C CG1 . VAL B 1 344 ? 161.974 192.629 162.397 1.00 63.52  ? 344 VAL B CG1 1 
ATOM   5613 C CG2 . VAL B 1 344 ? 161.880 192.180 159.947 1.00 63.52  ? 344 VAL B CG2 1 
ATOM   5614 N N   . GLY B 1 345 ? 161.434 189.162 163.432 1.00 64.02  ? 345 GLY B N   1 
ATOM   5615 C CA  . GLY B 1 345 ? 161.358 188.764 164.826 1.00 64.02  ? 345 GLY B CA  1 
ATOM   5616 C C   . GLY B 1 345 ? 162.291 187.635 165.208 1.00 64.02  ? 345 GLY B C   1 
ATOM   5617 O O   . GLY B 1 345 ? 162.510 187.410 166.402 1.00 64.02  ? 345 GLY B O   1 
ATOM   5618 N N   . PHE B 1 346 ? 162.834 186.913 164.231 1.00 61.71  ? 346 PHE B N   1 
ATOM   5619 C CA  . PHE B 1 346 ? 163.753 185.819 164.531 1.00 61.71  ? 346 PHE B CA  1 
ATOM   5620 C C   . PHE B 1 346 ? 165.209 186.258 164.665 1.00 61.71  ? 346 PHE B C   1 
ATOM   5621 O O   . PHE B 1 346 ? 166.067 185.410 164.921 1.00 61.71  ? 346 PHE B O   1 
ATOM   5622 C CB  . PHE B 1 346 ? 163.642 184.730 163.461 1.00 61.71  ? 346 PHE B CB  1 
ATOM   5623 C CG  . PHE B 1 346 ? 162.454 183.830 163.638 1.00 61.71  ? 346 PHE B CG  1 
ATOM   5624 C CD1 . PHE B 1 346 ? 161.950 183.568 164.899 1.00 61.71  ? 346 PHE B CD1 1 
ATOM   5625 C CD2 . PHE B 1 346 ? 161.837 183.250 162.544 1.00 61.71  ? 346 PHE B CD2 1 
ATOM   5626 C CE1 . PHE B 1 346 ? 160.856 182.745 165.066 1.00 61.71  ? 346 PHE B CE1 1 
ATOM   5627 C CE2 . PHE B 1 346 ? 160.741 182.425 162.706 1.00 61.71  ? 346 PHE B CE2 1 
ATOM   5628 C CZ  . PHE B 1 346 ? 160.252 182.173 163.969 1.00 61.71  ? 346 PHE B CZ  1 
ATOM   5629 N N   . ILE B 1 347 ? 165.511 187.549 164.491 1.00 58.19  ? 347 ILE B N   1 
ATOM   5630 C CA  . ILE B 1 347 ? 166.892 188.019 164.668 1.00 58.19  ? 347 ILE B CA  1 
ATOM   5631 C C   . ILE B 1 347 ? 167.411 187.799 166.082 1.00 58.19  ? 347 ILE B C   1 
ATOM   5632 O O   . ILE B 1 347 ? 168.593 187.435 166.236 1.00 58.19  ? 347 ILE B O   1 
ATOM   5633 C CB  . ILE B 1 347 ? 167.015 189.477 164.201 1.00 58.19  ? 347 ILE B CB  1 
ATOM   5634 C CG1 . ILE B 1 347 ? 166.467 189.622 162.782 1.00 58.19  ? 347 ILE B CG1 1 
ATOM   5635 C CG2 . ILE B 1 347 ? 168.462 189.931 164.255 1.00 58.19  ? 347 ILE B CG2 1 
ATOM   5636 C CD1 . ILE B 1 347 ? 166.713 190.977 162.166 1.00 58.19  ? 347 ILE B CD1 1 
ATOM   5637 N N   . PRO B 1 348 ? 166.635 188.021 167.152 1.00 58.45  ? 348 PRO B N   1 
ATOM   5638 C CA  . PRO B 1 348 ? 167.144 187.692 168.492 1.00 58.45  ? 348 PRO B CA  1 
ATOM   5639 C C   . PRO B 1 348 ? 167.618 186.258 168.629 1.00 58.45  ? 348 PRO B C   1 
ATOM   5640 O O   . PRO B 1 348 ? 168.543 185.999 169.408 1.00 58.45  ? 348 PRO B O   1 
ATOM   5641 C CB  . PRO B 1 348 ? 165.939 187.978 169.395 1.00 58.45  ? 348 PRO B CB  1 
ATOM   5642 C CG  . PRO B 1 348 ? 165.229 189.064 168.705 1.00 58.45  ? 348 PRO B CG  1 
ATOM   5643 C CD  . PRO B 1 348 ? 165.374 188.783 167.237 1.00 58.45  ? 348 PRO B CD  1 
ATOM   5644 N N   . PHE B 1 349 ? 167.026 185.316 167.891 1.00 58.19  ? 349 PHE B N   1 
ATOM   5645 C CA  . PHE B 1 349 ? 167.553 183.956 167.889 1.00 58.19  ? 349 PHE B CA  1 
ATOM   5646 C C   . PHE B 1 349 ? 168.980 183.921 167.361 1.00 58.19  ? 349 PHE B C   1 
ATOM   5647 O O   . PHE B 1 349 ? 169.839 183.234 167.924 1.00 58.19  ? 349 PHE B O   1 
ATOM   5648 C CB  . PHE B 1 349 ? 166.661 183.036 167.059 1.00 58.19  ? 349 PHE B CB  1 
ATOM   5649 C CG  . PHE B 1 349 ? 167.229 181.660 166.870 1.00 58.19  ? 349 PHE B CG  1 
ATOM   5650 C CD1 . PHE B 1 349 ? 167.215 180.745 167.906 1.00 58.19  ? 349 PHE B CD1 1 
ATOM   5651 C CD2 . PHE B 1 349 ? 167.784 181.285 165.661 1.00 58.19  ? 349 PHE B CD2 1 
ATOM   5652 C CE1 . PHE B 1 349 ? 167.741 179.483 167.739 1.00 58.19  ? 349 PHE B CE1 1 
ATOM   5653 C CE2 . PHE B 1 349 ? 168.312 180.023 165.490 1.00 58.19  ? 349 PHE B CE2 1 
ATOM   5654 C CZ  . PHE B 1 349 ? 168.290 179.122 166.530 1.00 58.19  ? 349 PHE B CZ  1 
ATOM   5655 N N   . VAL B 1 350 ? 169.254 184.659 166.282 1.00 56.37  ? 350 VAL B N   1 
ATOM   5656 C CA  . VAL B 1 350 ? 170.606 184.698 165.733 1.00 56.37  ? 350 VAL B CA  1 
ATOM   5657 C C   . VAL B 1 350 ? 171.574 185.302 166.738 1.00 56.37  ? 350 VAL B C   1 
ATOM   5658 O O   . VAL B 1 350 ? 172.685 184.793 166.934 1.00 56.37  ? 350 VAL B O   1 
ATOM   5659 C CB  . VAL B 1 350 ? 170.627 185.473 164.404 1.00 56.37  ? 350 VAL B CB  1 
ATOM   5660 C CG1 . VAL B 1 350 ? 172.054 185.654 163.920 1.00 56.37  ? 350 VAL B CG1 1 
ATOM   5661 C CG2 . VAL B 1 350 ? 169.829 184.744 163.372 1.00 56.37  ? 350 VAL B CG2 1 
ATOM   5662 N N   . ILE B 1 351 ? 171.175 186.396 167.389 1.00 56.13  ? 351 ILE B N   1 
ATOM   5663 C CA  . ILE B 1 351 ? 172.077 187.036 168.346 1.00 56.13  ? 351 ILE B CA  1 
ATOM   5664 C C   . ILE B 1 351 ? 172.360 186.109 169.525 1.00 56.13  ? 351 ILE B C   1 
ATOM   5665 O O   . ILE B 1 351 ? 173.512 185.967 169.965 1.00 56.13  ? 351 ILE B O   1 
ATOM   5666 C CB  . ILE B 1 351 ? 171.500 188.387 168.805 1.00 56.13  ? 351 ILE B CB  1 
ATOM   5667 C CG1 . ILE B 1 351 ? 171.332 189.323 167.608 1.00 56.13  ? 351 ILE B CG1 1 
ATOM   5668 C CG2 . ILE B 1 351 ? 172.402 189.021 169.845 1.00 56.13  ? 351 ILE B CG2 1 
ATOM   5669 C CD1 . ILE B 1 351 ? 170.589 190.595 167.928 1.00 56.13  ? 351 ILE B CD1 1 
ATOM   5670 N N   . ALA B 1 352 ? 171.319 185.459 170.053 1.00 54.87  ? 352 ALA B N   1 
ATOM   5671 C CA  . ALA B 1 352 ? 171.503 184.544 171.173 1.00 54.87  ? 352 ALA B CA  1 
ATOM   5672 C C   . ALA B 1 352 ? 172.374 183.357 170.786 1.00 54.87  ? 352 ALA B C   1 
ATOM   5673 O O   . ALA B 1 352 ? 173.228 182.921 171.569 1.00 54.87  ? 352 ALA B O   1 
ATOM   5674 C CB  . ALA B 1 352 ? 170.147 184.068 171.685 1.00 54.87  ? 352 ALA B CB  1 
ATOM   5675 N N   . MET B 1 353 ? 172.174 182.814 169.583 1.00 56.45  ? 353 MET B N   1 
ATOM   5676 C CA  . MET B 1 353 ? 173.007 181.705 169.134 1.00 56.45  ? 353 MET B CA  1 
ATOM   5677 C C   . MET B 1 353 ? 174.458 182.134 168.974 1.00 56.45  ? 353 MET B C   1 
ATOM   5678 O O   . MET B 1 353 ? 175.373 181.369 169.293 1.00 56.45  ? 353 MET B O   1 
ATOM   5679 C CB  . MET B 1 353 ? 172.474 181.133 167.824 1.00 56.45  ? 353 MET B CB  1 
ATOM   5680 C CG  . MET B 1 353 ? 172.784 179.663 167.661 1.00 56.45  ? 353 MET B CG  1 
ATOM   5681 S SD  . MET B 1 353 ? 171.880 178.862 166.334 1.00 56.45  ? 353 MET B SD  1 
ATOM   5682 C CE  . MET B 1 353 ? 173.090 177.644 165.835 1.00 56.45  ? 353 MET B CE  1 
ATOM   5683 N N   . GLY B 1 354 ? 174.691 183.345 168.467 1.00 52.38  ? 354 GLY B N   1 
ATOM   5684 C CA  . GLY B 1 354 ? 176.053 183.842 168.380 1.00 52.38  ? 354 GLY B CA  1 
ATOM   5685 C C   . GLY B 1 354 ? 176.713 183.957 169.740 1.00 52.38  ? 354 GLY B C   1 
ATOM   5686 O O   . GLY B 1 354 ? 177.878 183.587 169.911 1.00 52.38  ? 354 GLY B O   1 
ATOM   5687 N N   . ILE B 1 355 ? 175.972 184.460 170.730 1.00 52.74  ? 355 ILE B N   1 
ATOM   5688 C CA  . ILE B 1 355 ? 176.508 184.540 172.089 1.00 52.74  ? 355 ILE B CA  1 
ATOM   5689 C C   . ILE B 1 355 ? 176.845 183.148 172.615 1.00 52.74  ? 355 ILE B C   1 
ATOM   5690 O O   . ILE B 1 355 ? 177.914 182.927 173.203 1.00 52.74  ? 355 ILE B O   1 
ATOM   5691 C CB  . ILE B 1 355 ? 175.516 185.268 173.014 1.00 52.74  ? 355 ILE B CB  1 
ATOM   5692 C CG1 . ILE B 1 355 ? 175.488 186.761 172.698 1.00 52.74  ? 355 ILE B CG1 1 
ATOM   5693 C CG2 . ILE B 1 355 ? 175.880 185.045 174.470 1.00 52.74  ? 355 ILE B CG2 1 
ATOM   5694 C CD1 . ILE B 1 355 ? 174.537 187.545 173.565 1.00 52.74  ? 355 ILE B CD1 1 
ATOM   5695 N N   . GLY B 1 356 ? 175.941 182.189 172.409 1.00 51.93  ? 356 GLY B N   1 
ATOM   5696 C CA  . GLY B 1 356 ? 176.189 180.836 172.882 1.00 51.93  ? 356 GLY B CA  1 
ATOM   5697 C C   . GLY B 1 356 ? 177.396 180.191 172.228 1.00 51.93  ? 356 GLY B C   1 
ATOM   5698 O O   . GLY B 1 356 ? 178.202 179.539 172.896 1.00 51.93  ? 356 GLY B O   1 
ATOM   5699 N N   . LEU B 1 357 ? 177.534 180.357 170.909 1.00 50.41  ? 357 LEU B N   1 
ATOM   5700 C CA  . LEU B 1 357 ? 178.691 179.807 170.209 1.00 50.41  ? 357 LEU B CA  1 
ATOM   5701 C C   . LEU B 1 357 ? 179.980 180.452 170.694 1.00 50.41  ? 357 LEU B C   1 
ATOM   5702 O O   . LEU B 1 357 ? 180.995 179.768 170.872 1.00 50.41  ? 357 LEU B O   1 
ATOM   5703 C CB  . LEU B 1 357 ? 178.542 179.996 168.699 1.00 50.41  ? 357 LEU B CB  1 
ATOM   5704 C CG  . LEU B 1 357 ? 177.369 179.338 167.975 1.00 50.41  ? 357 LEU B CG  1 
ATOM   5705 C CD1 . LEU B 1 357 ? 177.040 180.117 166.722 1.00 50.41  ? 357 LEU B CD1 1 
ATOM   5706 C CD2 . LEU B 1 357 ? 177.668 177.897 167.633 1.00 50.41  ? 357 LEU B CD2 1 
ATOM   5707 N N   . GLY B 1 358 ? 179.963 181.769 170.906 1.00 49.74  ? 358 GLY B N   1 
ATOM   5708 C CA  . GLY B 1 358 ? 181.149 182.436 171.415 1.00 49.74  ? 358 GLY B CA  1 
ATOM   5709 C C   . GLY B 1 358 ? 181.558 181.935 172.785 1.00 49.74  ? 358 GLY B C   1 
ATOM   5710 O O   . GLY B 1 358 ? 182.747 181.768 173.065 1.00 49.74  ? 358 GLY B O   1 
ATOM   5711 N N   . VAL B 1 359 ? 180.581 181.696 173.661 1.00 50.65  ? 359 VAL B N   1 
ATOM   5712 C CA  . VAL B 1 359 ? 180.894 181.170 174.987 1.00 50.65  ? 359 VAL B CA  1 
ATOM   5713 C C   . VAL B 1 359 ? 181.434 179.744 174.893 1.00 50.65  ? 359 VAL B C   1 
ATOM   5714 O O   . VAL B 1 359 ? 182.433 179.397 175.540 1.00 50.65  ? 359 VAL B O   1 
ATOM   5715 C CB  . VAL B 1 359 ? 179.653 181.251 175.893 1.00 50.65  ? 359 VAL B CB  1 
ATOM   5716 C CG1 . VAL B 1 359 ? 179.815 180.354 177.101 1.00 50.65  ? 359 VAL B CG1 1 
ATOM   5717 C CG2 . VAL B 1 359 ? 179.415 182.684 176.325 1.00 50.65  ? 359 VAL B CG2 1 
ATOM   5718 N N   . SER B 1 360 ? 180.791 178.899 174.084 1.00 50.33  ? 360 SER B N   1 
ATOM   5719 C CA  . SER B 1 360 ? 181.176 177.492 174.025 1.00 50.33  ? 360 SER B CA  1 
ATOM   5720 C C   . SER B 1 360 ? 182.546 177.306 173.383 1.00 50.33  ? 360 SER B C   1 
ATOM   5721 O O   . SER B 1 360 ? 183.304 176.414 173.781 1.00 50.33  ? 360 SER B O   1 
ATOM   5722 C CB  . SER B 1 360 ? 180.121 176.691 173.270 1.00 50.33  ? 360 SER B CB  1 
ATOM   5723 O OG  . SER B 1 360 ? 180.232 175.311 173.564 1.00 50.33  ? 360 SER B OG  1 
ATOM   5724 N N   . SER B 1 361 ? 182.877 178.119 172.376 1.00 49.91  ? 361 SER B N   1 
ATOM   5725 C CA  . SER B 1 361 ? 184.174 177.986 171.722 1.00 49.91  ? 361 SER B CA  1 
ATOM   5726 C C   . SER B 1 361 ? 185.326 178.271 172.671 1.00 49.91  ? 361 SER B C   1 
ATOM   5727 O O   . SER B 1 361 ? 186.446 177.813 172.425 1.00 49.91  ? 361 SER B O   1 
ATOM   5728 C CB  . SER B 1 361 ? 184.254 178.917 170.514 1.00 49.91  ? 361 SER B CB  1 
ATOM   5729 O OG  . SER B 1 361 ? 184.426 180.261 170.920 1.00 49.91  ? 361 SER B OG  1 
ATOM   5730 N N   . GLN B 1 362 ? 185.082 179.023 173.741 1.00 50.27  ? 362 GLN B N   1 
ATOM   5731 C CA  . GLN B 1 362 ? 186.085 179.232 174.773 1.00 50.27  ? 362 GLN B CA  1 
ATOM   5732 C C   . GLN B 1 362 ? 185.992 178.200 175.885 1.00 50.27  ? 362 GLN B C   1 
ATOM   5733 O O   . GLN B 1 362 ? 187.016 177.845 176.479 1.00 50.27  ? 362 GLN B O   1 
ATOM   5734 C CB  . GLN B 1 362 ? 185.948 180.634 175.369 1.00 50.27  ? 362 GLN B CB  1 
ATOM   5735 C CG  . GLN B 1 362 ? 186.329 181.751 174.419 1.00 50.27  ? 362 GLN B CG  1 
ATOM   5736 C CD  . GLN B 1 362 ? 187.818 182.018 174.411 1.00 50.27  ? 362 GLN B CD  1 
ATOM   5737 O OE1 . GLN B 1 362 ? 188.437 182.115 173.352 1.00 50.27  ? 362 GLN B OE1 1 
ATOM   5738 N NE2 . GLN B 1 362 ? 188.405 182.131 175.596 1.00 50.27  ? 362 GLN B NE2 1 
ATOM   5739 N N   . LEU B 1 363 ? 184.786 177.711 176.179 1.00 51.17  ? 363 LEU B N   1 
ATOM   5740 C CA  . LEU B 1 363 ? 184.634 176.732 177.250 1.00 51.17  ? 363 LEU B CA  1 
ATOM   5741 C C   . LEU B 1 363 ? 185.122 175.342 176.859 1.00 51.17  ? 363 LEU B C   1 
ATOM   5742 O O   . LEU B 1 363 ? 185.467 174.556 177.745 1.00 51.17  ? 363 LEU B O   1 
ATOM   5743 C CB  . LEU B 1 363 ? 183.174 176.658 177.694 1.00 51.17  ? 363 LEU B CB  1 
ATOM   5744 C CG  . LEU B 1 363 ? 182.695 177.740 178.660 1.00 51.17  ? 363 LEU B CG  1 
ATOM   5745 C CD1 . LEU B 1 363 ? 181.261 177.482 179.069 1.00 51.17  ? 363 LEU B CD1 1 
ATOM   5746 C CD2 . LEU B 1 363 ? 183.596 177.805 179.876 1.00 51.17  ? 363 LEU B CD2 1 
ATOM   5747 N N   . VAL B 1 364 ? 185.164 175.019 175.564 1.00 52.69  ? 364 VAL B N   1 
ATOM   5748 C CA  . VAL B 1 364 ? 185.552 173.678 175.132 1.00 52.69  ? 364 VAL B CA  1 
ATOM   5749 C C   . VAL B 1 364 ? 186.996 173.331 175.466 1.00 52.69  ? 364 VAL B C   1 
ATOM   5750 O O   . VAL B 1 364 ? 187.385 172.168 175.341 1.00 52.69  ? 364 VAL B O   1 
ATOM   5751 C CB  . VAL B 1 364 ? 185.327 173.490 173.615 1.00 52.69  ? 364 VAL B CB  1 
ATOM   5752 C CG1 . VAL B 1 364 ? 183.850 173.377 173.297 1.00 52.69  ? 364 VAL B CG1 1 
ATOM   5753 C CG2 . VAL B 1 364 ? 185.962 174.624 172.837 1.00 52.69  ? 364 VAL B CG2 1 
ATOM   5754 N N   . SER B 1 365 ? 187.805 174.305 175.877 1.00 56.07  ? 365 SER B N   1 
ATOM   5755 C CA  . SER B 1 365 ? 189.198 174.037 176.206 1.00 56.07  ? 365 SER B CA  1 
ATOM   5756 C C   . SER B 1 365 ? 189.385 173.475 177.608 1.00 56.07  ? 365 SER B C   1 
ATOM   5757 O O   . SER B 1 365 ? 190.505 173.083 177.951 1.00 56.07  ? 365 SER B O   1 
ATOM   5758 C CB  . SER B 1 365 ? 190.028 175.313 176.062 1.00 56.07  ? 365 SER B CB  1 
ATOM   5759 O OG  . SER B 1 365 ? 190.062 175.752 174.717 1.00 56.07  ? 365 SER B OG  1 
ATOM   5760 N N   . ARG B 1 366 ? 188.333 173.426 178.423 1.00 58.28  ? 366 ARG B N   1 
ATOM   5761 C CA  . ARG B 1 366 ? 188.473 172.978 179.802 1.00 58.28  ? 366 ARG B CA  1 
ATOM   5762 C C   . ARG B 1 366 ? 187.468 171.891 180.164 1.00 58.28  ? 366 ARG B C   1 
ATOM   5763 O O   . ARG B 1 366 ? 187.758 171.027 180.996 1.00 58.28  ? 366 ARG B O   1 
ATOM   5764 C CB  . ARG B 1 366 ? 188.319 174.160 180.759 1.00 58.28  ? 366 ARG B CB  1 
ATOM   5765 C CG  . ARG B 1 366 ? 188.806 173.873 182.163 1.00 58.28  ? 366 ARG B CG  1 
ATOM   5766 C CD  . ARG B 1 366 ? 188.559 175.047 183.087 1.00 58.28  ? 366 ARG B CD  1 
ATOM   5767 N NE  . ARG B 1 366 ? 188.100 174.608 184.398 1.00 58.28  ? 366 ARG B NE  1 
ATOM   5768 C CZ  . ARG B 1 366 ? 187.379 175.351 185.226 1.00 58.28  ? 366 ARG B CZ  1 
ATOM   5769 N NH1 . ARG B 1 366 ? 187.027 176.587 184.915 1.00 58.28  ? 366 ARG B NH1 1 
ATOM   5770 N NH2 . ARG B 1 366 ? 187.002 174.840 186.393 1.00 58.28  ? 366 ARG B NH2 1 
ATOM   5771 N N   . PHE B 1 367 ? 186.292 171.920 179.547 1.00 56.19  ? 367 PHE B N   1 
ATOM   5772 C CA  . PHE B 1 367 ? 185.200 171.026 179.901 1.00 56.19  ? 367 PHE B CA  1 
ATOM   5773 C C   . PHE B 1 367 ? 184.980 169.992 178.805 1.00 56.19  ? 367 PHE B C   1 
ATOM   5774 O O   . PHE B 1 367 ? 185.142 170.285 177.618 1.00 56.19  ? 367 PHE B O   1 
ATOM   5775 C CB  . PHE B 1 367 ? 183.909 171.812 180.142 1.00 56.19  ? 367 PHE B CB  1 
ATOM   5776 C CG  . PHE B 1 367 ? 183.925 172.632 181.399 1.00 56.19  ? 367 PHE B CG  1 
ATOM   5777 C CD1 . PHE B 1 367 ? 183.819 172.027 182.637 1.00 56.19  ? 367 PHE B CD1 1 
ATOM   5778 C CD2 . PHE B 1 367 ? 184.051 174.007 181.342 1.00 56.19  ? 367 PHE B CD2 1 
ATOM   5779 C CE1 . PHE B 1 367 ? 183.836 172.776 183.791 1.00 56.19  ? 367 PHE B CE1 1 
ATOM   5780 C CE2 . PHE B 1 367 ? 184.069 174.760 182.494 1.00 56.19  ? 367 PHE B CE2 1 
ATOM   5781 C CZ  . PHE B 1 367 ? 183.960 174.144 183.719 1.00 56.19  ? 367 PHE B CZ  1 
ATOM   5782 N N   . SER B 1 368 ? 184.609 168.784 179.216 1.00 55.27  ? 368 SER B N   1 
ATOM   5783 C CA  . SER B 1 368 ? 184.341 167.716 178.271 1.00 55.27  ? 368 SER B CA  1 
ATOM   5784 C C   . SER B 1 368 ? 183.120 168.059 177.419 1.00 55.27  ? 368 SER B C   1 
ATOM   5785 O O   . SER B 1 368 ? 182.224 168.778 177.868 1.00 55.27  ? 368 SER B O   1 
ATOM   5786 C CB  . SER B 1 368 ? 184.109 166.404 179.013 1.00 55.27  ? 368 SER B CB  1 
ATOM   5787 O OG  . SER B 1 368 ? 183.948 165.321 178.117 1.00 55.27  ? 368 SER B OG  1 
ATOM   5788 N N   . PRO B 1 369 ? 183.068 167.569 176.177 1.00 55.62  ? 369 PRO B N   1 
ATOM   5789 C CA  . PRO B 1 369 ? 181.908 167.871 175.323 1.00 55.62  ? 369 PRO B CA  1 
ATOM   5790 C C   . PRO B 1 369 ? 180.577 167.427 175.904 1.00 55.62  ? 369 PRO B C   1 
ATOM   5791 O O   . PRO B 1 369 ? 179.560 168.088 175.658 1.00 55.62  ? 369 PRO B O   1 
ATOM   5792 C CB  . PRO B 1 369 ? 182.229 167.127 174.017 1.00 55.62  ? 369 PRO B CB  1 
ATOM   5793 C CG  . PRO B 1 369 ? 183.402 166.248 174.322 1.00 55.62  ? 369 PRO B CG  1 
ATOM   5794 C CD  . PRO B 1 369 ? 184.143 166.911 175.422 1.00 55.62  ? 369 PRO B CD  1 
ATOM   5795 N N   . ARG B 1 370 ? 180.543 166.330 176.665 1.00 57.28  ? 370 ARG B N   1 
ATOM   5796 C CA  . ARG B 1 370 ? 179.282 165.879 177.247 1.00 57.28  ? 370 ARG B CA  1 
ATOM   5797 C C   . ARG B 1 370 ? 178.746 166.887 178.260 1.00 57.28  ? 370 ARG B C   1 
ATOM   5798 O O   . ARG B 1 370 ? 177.534 167.134 178.321 1.00 57.28  ? 370 ARG B O   1 
ATOM   5799 C CB  . ARG B 1 370 ? 179.461 164.499 177.885 1.00 57.28  ? 370 ARG B CB  1 
ATOM   5800 C CG  . ARG B 1 370 ? 180.389 164.464 179.085 1.00 57.28  ? 370 ARG B CG  1 
ATOM   5801 C CD  . ARG B 1 370 ? 180.188 163.210 179.916 1.00 57.28  ? 370 ARG B CD  1 
ATOM   5802 N NE  . ARG B 1 370 ? 181.114 162.148 179.545 1.00 57.28  ? 370 ARG B NE  1 
ATOM   5803 C CZ  . ARG B 1 370 ? 181.174 160.967 180.143 1.00 57.28  ? 370 ARG B CZ  1 
ATOM   5804 N NH1 . ARG B 1 370 ? 180.365 160.656 181.140 1.00 57.28  ? 370 ARG B NH1 1 
ATOM   5805 N NH2 . ARG B 1 370 ? 182.070 160.076 179.731 1.00 57.28  ? 370 ARG B NH2 1 
ATOM   5806 N N   . VAL B 1 371 ? 179.635 167.492 179.052 1.00 55.39  ? 371 VAL B N   1 
ATOM   5807 C CA  . VAL B 1 371 ? 179.207 168.468 180.049 1.00 55.39  ? 371 VAL B CA  1 
ATOM   5808 C C   . VAL B 1 371 ? 178.590 169.686 179.374 1.00 55.39  ? 371 VAL B C   1 
ATOM   5809 O O   . VAL B 1 371 ? 177.531 170.175 179.787 1.00 55.39  ? 371 VAL B O   1 
ATOM   5810 C CB  . VAL B 1 371 ? 180.391 168.859 180.951 1.00 55.39  ? 371 VAL B CB  1 
ATOM   5811 C CG1 . VAL B 1 371 ? 179.983 169.949 181.921 1.00 55.39  ? 371 VAL B CG1 1 
ATOM   5812 C CG2 . VAL B 1 371 ? 180.904 167.646 181.700 1.00 55.39  ? 371 VAL B CG2 1 
ATOM   5813 N N   . LEU B 1 372 ? 179.234 170.189 178.320 1.00 54.32  ? 372 LEU B N   1 
ATOM   5814 C CA  . LEU B 1 372 ? 178.704 171.351 177.615 1.00 54.32  ? 372 LEU B CA  1 
ATOM   5815 C C   . LEU B 1 372 ? 177.407 171.017 176.887 1.00 54.32  ? 372 LEU B C   1 
ATOM   5816 O O   . LEU B 1 372 ? 176.500 171.854 176.806 1.00 54.32  ? 372 LEU B O   1 
ATOM   5817 C CB  . LEU B 1 372 ? 179.752 171.889 176.645 1.00 54.32  ? 372 LEU B CB  1 
ATOM   5818 C CG  . LEU B 1 372 ? 181.021 172.415 177.316 1.00 54.32  ? 372 LEU B CG  1 
ATOM   5819 C CD1 . LEU B 1 372 ? 182.178 172.407 176.346 1.00 54.32  ? 372 LEU B CD1 1 
ATOM   5820 C CD2 . LEU B 1 372 ? 180.792 173.809 177.861 1.00 54.32  ? 372 LEU B CD2 1 
ATOM   5821 N N   . THR B 1 373 ? 177.301 169.798 176.351 1.00 55.99  ? 373 THR B N   1 
ATOM   5822 C CA  . THR B 1 373 ? 176.052 169.374 175.728 1.00 55.99  ? 373 THR B CA  1 
ATOM   5823 C C   . THR B 1 373 ? 174.910 169.367 176.736 1.00 55.99  ? 373 THR B C   1 
ATOM   5824 O O   . THR B 1 373 ? 173.813 169.860 176.445 1.00 55.99  ? 373 THR B O   1 
ATOM   5825 C CB  . THR B 1 373 ? 176.223 167.992 175.100 1.00 55.99  ? 373 THR B CB  1 
ATOM   5826 O OG1 . THR B 1 373 ? 177.324 168.016 174.185 1.00 55.99  ? 373 THR B OG1 1 
ATOM   5827 C CG2 . THR B 1 373 ? 174.966 167.584 174.355 1.00 55.99  ? 373 THR B CG2 1 
ATOM   5828 N N   . ILE B 1 374 ? 175.154 168.831 177.934 1.00 58.66  ? 374 ILE B N   1 
ATOM   5829 C CA  . ILE B 1 374 ? 174.124 168.833 178.973 1.00 58.66  ? 374 ILE B CA  1 
ATOM   5830 C C   . ILE B 1 374 ? 173.787 170.261 179.389 1.00 58.66  ? 374 ILE B C   1 
ATOM   5831 O O   . ILE B 1 374 ? 172.619 170.598 179.625 1.00 58.66  ? 374 ILE B O   1 
ATOM   5832 C CB  . ILE B 1 374 ? 174.576 167.983 180.175 1.00 58.66  ? 374 ILE B CB  1 
ATOM   5833 C CG1 . ILE B 1 374 ? 174.766 166.524 179.758 1.00 58.66  ? 374 ILE B CG1 1 
ATOM   5834 C CG2 . ILE B 1 374 ? 173.568 168.076 181.306 1.00 58.66  ? 374 ILE B CG2 1 
ATOM   5835 C CD1 . ILE B 1 374 ? 173.498 165.851 179.293 1.00 58.66  ? 374 ILE B CD1 1 
ATOM   5836 N N   . GLY B 1 375 ? 174.803 171.123 179.483 1.00 58.61  ? 375 GLY B N   1 
ATOM   5837 C CA  . GLY B 1 375 ? 174.558 172.505 179.863 1.00 58.61  ? 375 GLY B CA  1 
ATOM   5838 C C   . GLY B 1 375 ? 173.679 173.246 178.874 1.00 58.61  ? 375 GLY B C   1 
ATOM   5839 O O   . GLY B 1 375 ? 172.785 173.999 179.268 1.00 58.61  ? 375 GLY B O   1 
ATOM   5840 N N   . GLY B 1 376 ? 173.927 173.057 177.577 1.00 57.78  ? 376 GLY B N   1 
ATOM   5841 C CA  . GLY B 1 376 ? 173.055 173.655 176.576 1.00 57.78  ? 376 GLY B CA  1 
ATOM   5842 C C   . GLY B 1 376 ? 171.662 173.049 176.573 1.00 57.78  ? 376 GLY B C   1 
ATOM   5843 O O   . GLY B 1 376 ? 170.658 173.761 176.425 1.00 57.78  ? 376 GLY B O   1 
ATOM   5844 N N   . GLY B 1 377 ? 171.581 171.727 176.734 1.00 59.92  ? 377 GLY B N   1 
ATOM   5845 C CA  . GLY B 1 377 ? 170.289 171.071 176.754 1.00 59.92  ? 377 GLY B CA  1 
ATOM   5846 C C   . GLY B 1 377 ? 169.416 171.501 177.913 1.00 59.92  ? 377 GLY B C   1 
ATOM   5847 O O   . GLY B 1 377 ? 168.192 171.506 177.796 1.00 59.92  ? 377 GLY B O   1 
ATOM   5848 N N   . TYR B 1 378 ? 170.027 171.853 179.045 1.00 59.31  ? 378 TYR B N   1 
ATOM   5849 C CA  . TYR B 1 378 ? 169.257 172.363 180.176 1.00 59.31  ? 378 TYR B CA  1 
ATOM   5850 C C   . TYR B 1 378 ? 168.445 173.593 179.776 1.00 59.31  ? 378 TYR B C   1 
ATOM   5851 O O   . TYR B 1 378 ? 167.220 173.642 179.969 1.00 59.31  ? 378 TYR B O   1 
ATOM   5852 C CB  . TYR B 1 378 ? 170.210 172.683 181.331 1.00 59.31  ? 378 TYR B CB  1 
ATOM   5853 C CG  . TYR B 1 378 ? 169.579 173.371 182.518 1.00 59.31  ? 378 TYR B CG  1 
ATOM   5854 C CD1 . TYR B 1 378 ? 168.984 172.638 183.533 1.00 59.31  ? 378 TYR B CD1 1 
ATOM   5855 C CD2 . TYR B 1 378 ? 169.597 174.754 182.635 1.00 59.31  ? 378 TYR B CD2 1 
ATOM   5856 C CE1 . TYR B 1 378 ? 168.412 173.262 184.619 1.00 59.31  ? 378 TYR B CE1 1 
ATOM   5857 C CE2 . TYR B 1 378 ? 169.026 175.385 183.716 1.00 59.31  ? 378 TYR B CE2 1 
ATOM   5858 C CZ  . TYR B 1 378 ? 168.434 174.635 184.704 1.00 59.31  ? 378 TYR B CZ  1 
ATOM   5859 O OH  . TYR B 1 378 ? 167.865 175.260 185.787 1.00 59.31  ? 378 TYR B OH  1 
ATOM   5860 N N   . LEU B 1 379 ? 169.115 174.587 179.189 1.00 55.62  ? 379 LEU B N   1 
ATOM   5861 C CA  . LEU B 1 379 ? 168.431 175.804 178.765 1.00 55.62  ? 379 LEU B CA  1 
ATOM   5862 C C   . LEU B 1 379 ? 167.418 175.515 177.667 1.00 55.62  ? 379 LEU B C   1 
ATOM   5863 O O   . LEU B 1 379 ? 166.310 176.070 177.674 1.00 55.62  ? 379 LEU B O   1 
ATOM   5864 C CB  . LEU B 1 379 ? 169.449 176.839 178.290 1.00 55.62  ? 379 LEU B CB  1 
ATOM   5865 C CG  . LEU B 1 379 ? 170.443 177.362 179.325 1.00 55.62  ? 379 LEU B CG  1 
ATOM   5866 C CD1 . LEU B 1 379 ? 171.538 178.157 178.646 1.00 55.62  ? 379 LEU B CD1 1 
ATOM   5867 C CD2 . LEU B 1 379 ? 169.732 178.209 180.361 1.00 55.62  ? 379 LEU B CD2 1 
ATOM   5868 N N   . LEU B 1 380 ? 167.780 174.656 176.709 1.00 58.03  ? 380 LEU B N   1 
ATOM   5869 C CA  . LEU B 1 380 ? 166.844 174.342 175.632 1.00 58.03  ? 380 LEU B CA  1 
ATOM   5870 C C   . LEU B 1 380 ? 165.569 173.701 176.172 1.00 58.03  ? 380 LEU B C   1 
ATOM   5871 O O   . LEU B 1 380 ? 164.459 174.075 175.774 1.00 58.03  ? 380 LEU B O   1 
ATOM   5872 C CB  . LEU B 1 380 ? 167.511 173.428 174.606 1.00 58.03  ? 380 LEU B CB  1 
ATOM   5873 C CG  . LEU B 1 380 ? 166.697 173.111 173.352 1.00 58.03  ? 380 LEU B CG  1 
ATOM   5874 C CD1 . LEU B 1 380 ? 166.139 174.378 172.732 1.00 58.03  ? 380 LEU B CD1 1 
ATOM   5875 C CD2 . LEU B 1 380 ? 167.544 172.354 172.352 1.00 58.03  ? 380 LEU B CD2 1 
ATOM   5876 N N   . PHE B 1 381 ? 165.710 172.742 177.090 1.00 60.45  ? 381 PHE B N   1 
ATOM   5877 C CA  . PHE B 1 381 ? 164.550 172.066 177.660 1.00 60.45  ? 381 PHE B CA  1 
ATOM   5878 C C   . PHE B 1 381 ? 163.683 173.029 178.458 1.00 60.45  ? 381 PHE B C   1 
ATOM   5879 O O   . PHE B 1 381 ? 162.449 172.987 178.365 1.00 60.45  ? 381 PHE B O   1 
ATOM   5880 C CB  . PHE B 1 381 ? 165.016 170.903 178.534 1.00 60.45  ? 381 PHE B CB  1 
ATOM   5881 C CG  . PHE B 1 381 ? 163.901 170.047 179.051 1.00 60.45  ? 381 PHE B CG  1 
ATOM   5882 C CD1 . PHE B 1 381 ? 163.025 169.427 178.182 1.00 60.45  ? 381 PHE B CD1 1 
ATOM   5883 C CD2 . PHE B 1 381 ? 163.738 169.851 180.411 1.00 60.45  ? 381 PHE B CD2 1 
ATOM   5884 C CE1 . PHE B 1 381 ? 162.001 168.638 178.658 1.00 60.45  ? 381 PHE B CE1 1 
ATOM   5885 C CE2 . PHE B 1 381 ? 162.719 169.059 180.891 1.00 60.45  ? 381 PHE B CE2 1 
ATOM   5886 C CZ  . PHE B 1 381 ? 161.848 168.453 180.015 1.00 60.45  ? 381 PHE B CZ  1 
ATOM   5887 N N   . GLY B 1 382 ? 164.306 173.903 179.252 1.00 59.88  ? 382 GLY B N   1 
ATOM   5888 C CA  . GLY B 1 382 ? 163.525 174.889 179.984 1.00 59.88  ? 382 GLY B CA  1 
ATOM   5889 C C   . GLY B 1 382 ? 162.739 175.806 179.066 1.00 59.88  ? 382 GLY B C   1 
ATOM   5890 O O   . GLY B 1 382 ? 161.557 176.082 179.304 1.00 59.88  ? 382 GLY B O   1 
ATOM   5891 N N   . ALA B 1 383 ? 163.383 176.284 177.996 1.00 58.21  ? 383 ALA B N   1 
ATOM   5892 C CA  . ALA B 1 383 ? 162.698 177.159 177.050 1.00 58.21  ? 383 ALA B CA  1 
ATOM   5893 C C   . ALA B 1 383 ? 161.538 176.444 176.371 1.00 58.21  ? 383 ALA B C   1 
ATOM   5894 O O   . ALA B 1 383 ? 160.458 177.023 176.200 1.00 58.21  ? 383 ALA B O   1 
ATOM   5895 C CB  . ALA B 1 383 ? 163.686 177.682 176.011 1.00 58.21  ? 383 ALA B CB  1 
ATOM   5896 N N   . MET B 1 384 ? 161.738 175.185 175.973 1.00 61.52  ? 384 MET B N   1 
ATOM   5897 C CA  . MET B 1 384 ? 160.655 174.448 175.329 1.00 61.52  ? 384 MET B CA  1 
ATOM   5898 C C   . MET B 1 384 ? 159.486 174.223 176.279 1.00 61.52  ? 384 MET B C   1 
ATOM   5899 O O   . MET B 1 384 ? 158.326 174.338 175.872 1.00 61.52  ? 384 MET B O   1 
ATOM   5900 C CB  . MET B 1 384 ? 161.160 173.118 174.774 1.00 61.52  ? 384 MET B CB  1 
ATOM   5901 C CG  . MET B 1 384 ? 162.237 173.262 173.723 1.00 61.52  ? 384 MET B CG  1 
ATOM   5902 S SD  . MET B 1 384 ? 162.368 171.804 172.682 1.00 61.52  ? 384 MET B SD  1 
ATOM   5903 C CE  . MET B 1 384 ? 163.637 170.905 173.556 1.00 61.52  ? 384 MET B CE  1 
ATOM   5904 N N   . LEU B 1 385 ? 159.762 173.896 177.545 1.00 63.72  ? 385 LEU B N   1 
ATOM   5905 C CA  . LEU B 1 385 ? 158.664 173.726 178.497 1.00 63.72  ? 385 LEU B CA  1 
ATOM   5906 C C   . LEU B 1 385 ? 157.891 175.024 178.694 1.00 63.72  ? 385 LEU B C   1 
ATOM   5907 O O   . LEU B 1 385 ? 156.651 175.025 178.695 1.00 63.72  ? 385 LEU B O   1 
ATOM   5908 C CB  . LEU B 1 385 ? 159.181 173.215 179.839 1.00 63.72  ? 385 LEU B CB  1 
ATOM   5909 C CG  . LEU B 1 385 ? 159.781 171.815 179.887 1.00 63.72  ? 385 LEU B CG  1 
ATOM   5910 C CD1 . LEU B 1 385 ? 160.356 171.556 181.266 1.00 63.72  ? 385 LEU B CD1 1 
ATOM   5911 C CD2 . LEU B 1 385 ? 158.728 170.781 179.541 1.00 63.72  ? 385 LEU B CD2 1 
ATOM   5912 N N   . TYR B 1 386 ? 158.602 176.144 178.860 1.00 65.72  ? 386 TYR B N   1 
ATOM   5913 C CA  . TYR B 1 386 ? 157.903 177.411 179.045 1.00 65.72  ? 386 TYR B CA  1 
ATOM   5914 C C   . TYR B 1 386 ? 157.069 177.762 177.821 1.00 65.72  ? 386 TYR B C   1 
ATOM   5915 O O   . TYR B 1 386 ? 155.938 178.242 177.950 1.00 65.72  ? 386 TYR B O   1 
ATOM   5916 C CB  . TYR B 1 386 ? 158.887 178.536 179.355 1.00 65.72  ? 386 TYR B CB  1 
ATOM   5917 C CG  . TYR B 1 386 ? 158.211 179.884 179.451 1.00 65.72  ? 386 TYR B CG  1 
ATOM   5918 C CD1 . TYR B 1 386 ? 157.524 180.258 180.596 1.00 65.72  ? 386 TYR B CD1 1 
ATOM   5919 C CD2 . TYR B 1 386 ? 158.242 180.774 178.389 1.00 65.72  ? 386 TYR B CD2 1 
ATOM   5920 C CE1 . TYR B 1 386 ? 156.897 181.486 180.683 1.00 65.72  ? 386 TYR B CE1 1 
ATOM   5921 C CE2 . TYR B 1 386 ? 157.619 182.003 178.467 1.00 65.72  ? 386 TYR B CE2 1 
ATOM   5922 C CZ  . TYR B 1 386 ? 156.949 182.354 179.615 1.00 65.72  ? 386 TYR B CZ  1 
ATOM   5923 O OH  . TYR B 1 386 ? 156.329 183.577 179.694 1.00 65.72  ? 386 TYR B OH  1 
ATOM   5924 N N   . GLY B 1 387 ? 157.609 177.535 176.623 1.00 64.44  ? 387 GLY B N   1 
ATOM   5925 C CA  . GLY B 1 387 ? 156.839 177.802 175.421 1.00 64.44  ? 387 GLY B CA  1 
ATOM   5926 C C   . GLY B 1 387 ? 155.624 176.904 175.297 1.00 64.44  ? 387 GLY B C   1 
ATOM   5927 O O   . GLY B 1 387 ? 154.567 177.334 174.833 1.00 64.44  ? 387 GLY B O   1 
ATOM   5928 N N   . SER B 1 388 ? 155.758 175.643 175.706 1.00 65.18  ? 388 SER B N   1 
ATOM   5929 C CA  . SER B 1 388 ? 154.637 174.714 175.625 1.00 65.18  ? 388 SER B CA  1 
ATOM   5930 C C   . SER B 1 388 ? 153.516 175.103 176.577 1.00 65.18  ? 388 SER B C   1 
ATOM   5931 O O   . SER B 1 388 ? 152.336 175.011 176.222 1.00 65.18  ? 388 SER B O   1 
ATOM   5932 C CB  . SER B 1 388 ? 155.113 173.293 175.920 1.00 65.18  ? 388 SER B CB  1 
ATOM   5933 O OG  . SER B 1 388 ? 154.014 172.410 176.051 1.00 65.18  ? 388 SER B OG  1 
ATOM   5934 N N   . PHE B 1 389 ? 153.857 175.532 177.791 1.00 68.13  ? 389 PHE B N   1 
ATOM   5935 C CA  . PHE B 1 389 ? 152.833 175.732 178.810 1.00 68.13  ? 389 PHE B CA  1 
ATOM   5936 C C   . PHE B 1 389 ? 152.284 177.154 178.878 1.00 68.13  ? 389 PHE B C   1 
ATOM   5937 O O   . PHE B 1 389 ? 151.341 177.391 179.638 1.00 68.13  ? 389 PHE B O   1 
ATOM   5938 C CB  . PHE B 1 389 ? 153.376 175.333 180.184 1.00 68.13  ? 389 PHE B CB  1 
ATOM   5939 C CG  . PHE B 1 389 ? 153.342 173.855 180.437 1.00 68.13  ? 389 PHE B CG  1 
ATOM   5940 C CD1 . PHE B 1 389 ? 152.136 173.193 180.579 1.00 68.13  ? 389 PHE B CD1 1 
ATOM   5941 C CD2 . PHE B 1 389 ? 154.514 173.126 180.522 1.00 68.13  ? 389 PHE B CD2 1 
ATOM   5942 C CE1 . PHE B 1 389 ? 152.102 171.832 180.806 1.00 68.13  ? 389 PHE B CE1 1 
ATOM   5943 C CE2 . PHE B 1 389 ? 154.486 171.765 180.749 1.00 68.13  ? 389 PHE B CE2 1 
ATOM   5944 C CZ  . PHE B 1 389 ? 153.279 171.118 180.892 1.00 68.13  ? 389 PHE B CZ  1 
ATOM   5945 N N   . PHE B 1 390 ? 152.830 178.102 178.117 1.00 71.58  ? 390 PHE B N   1 
ATOM   5946 C CA  . PHE B 1 390 ? 152.395 179.492 178.226 1.00 71.58  ? 390 PHE B CA  1 
ATOM   5947 C C   . PHE B 1 390 ? 152.279 180.146 176.855 1.00 71.58  ? 390 PHE B C   1 
ATOM   5948 O O   . PHE B 1 390 ? 152.688 181.295 176.664 1.00 71.58  ? 390 PHE B O   1 
ATOM   5949 C CB  . PHE B 1 390 ? 153.345 180.297 179.112 1.00 71.58  ? 390 PHE B CB  1 
ATOM   5950 C CG  . PHE B 1 390 ? 153.200 180.009 180.576 1.00 71.58  ? 390 PHE B CG  1 
ATOM   5951 C CD1 . PHE B 1 390 ? 153.897 178.967 181.162 1.00 71.58  ? 390 PHE B CD1 1 
ATOM   5952 C CD2 . PHE B 1 390 ? 152.369 180.781 181.368 1.00 71.58  ? 390 PHE B CD2 1 
ATOM   5953 C CE1 . PHE B 1 390 ? 153.766 178.698 182.509 1.00 71.58  ? 390 PHE B CE1 1 
ATOM   5954 C CE2 . PHE B 1 390 ? 152.233 180.517 182.716 1.00 71.58  ? 390 PHE B CE2 1 
ATOM   5955 C CZ  . PHE B 1 390 ? 152.932 179.474 183.287 1.00 71.58  ? 390 PHE B CZ  1 
ATOM   5956 N N   . MET B 1 391 ? 151.711 179.438 175.881 1.00 71.65  ? 391 MET B N   1 
ATOM   5957 C CA  . MET B 1 391 ? 151.566 179.967 174.531 1.00 71.65  ? 391 MET B CA  1 
ATOM   5958 C C   . MET B 1 391 ? 150.150 179.739 174.029 1.00 71.65  ? 391 MET B C   1 
ATOM   5959 O O   . MET B 1 391 ? 149.604 178.642 174.179 1.00 71.65  ? 391 MET B O   1 
ATOM   5960 C CB  . MET B 1 391 ? 152.565 179.321 173.571 1.00 71.65  ? 391 MET B CB  1 
ATOM   5961 C CG  . MET B 1 391 ? 152.958 180.199 172.397 1.00 71.65  ? 391 MET B CG  1 
ATOM   5962 S SD  . MET B 1 391 ? 154.166 181.461 172.834 1.00 71.65  ? 391 MET B SD  1 
ATOM   5963 C CE  . MET B 1 391 ? 153.573 182.838 171.859 1.00 71.65  ? 391 MET B CE  1 
ATOM   5964 N N   . HIS B 1 392 ? 149.567 180.774 173.430 1.00 74.41  ? 392 HIS B N   1 
ATOM   5965 C CA  . HIS B 1 392 ? 148.276 180.666 172.763 1.00 74.41  ? 392 HIS B CA  1 
ATOM   5966 C C   . HIS B 1 392 ? 148.080 181.900 171.894 1.00 74.41  ? 392 HIS B C   1 
ATOM   5967 O O   . HIS B 1 392 ? 148.919 182.803 171.862 1.00 74.41  ? 392 HIS B O   1 
ATOM   5968 C CB  . HIS B 1 392 ? 147.131 180.496 173.768 1.00 74.41  ? 392 HIS B CB  1 
ATOM   5969 C CG  . HIS B 1 392 ? 146.960 181.653 174.700 1.00 74.41  ? 392 HIS B CG  1 
ATOM   5970 N ND1 . HIS B 1 392 ? 146.196 182.756 174.386 1.00 74.41  ? 392 HIS B ND1 1 
ATOM   5971 C CD2 . HIS B 1 392 ? 147.450 181.876 175.942 1.00 74.41  ? 392 HIS B CD2 1 
ATOM   5972 C CE1 . HIS B 1 392 ? 146.224 183.610 175.393 1.00 74.41  ? 392 HIS B CE1 1 
ATOM   5973 N NE2 . HIS B 1 392 ? 146.979 183.100 176.350 1.00 74.41  ? 392 HIS B NE2 1 
ATOM   5974 N N   . ARG B 1 393 ? 146.964 181.918 171.174 1.00 77.18  ? 393 ARG B N   1 
ATOM   5975 C CA  . ARG B 1 393 ? 146.664 183.019 170.271 1.00 77.18  ? 393 ARG B CA  1 
ATOM   5976 C C   . ARG B 1 393 ? 146.373 184.294 171.056 1.00 77.18  ? 393 ARG B C   1 
ATOM   5977 O O   . ARG B 1 393 ? 145.769 184.265 172.131 1.00 77.18  ? 393 ARG B O   1 
ATOM   5978 C CB  . ARG B 1 393 ? 145.472 182.658 169.384 1.00 77.18  ? 393 ARG B CB  1 
ATOM   5979 C CG  . ARG B 1 393 ? 145.118 183.692 168.332 1.00 77.18  ? 393 ARG B CG  1 
ATOM   5980 C CD  . ARG B 1 393 ? 143.984 183.190 167.451 1.00 77.18  ? 393 ARG B CD  1 
ATOM   5981 N NE  . ARG B 1 393 ? 143.556 184.187 166.477 1.00 77.18  ? 393 ARG B NE  1 
ATOM   5982 C CZ  . ARG B 1 393 ? 144.106 184.350 165.282 1.00 77.18  ? 393 ARG B CZ  1 
ATOM   5983 N NH1 . ARG B 1 393 ? 145.106 183.589 164.872 1.00 77.18  ? 393 ARG B NH1 1 
ATOM   5984 N NH2 . ARG B 1 393 ? 143.636 185.298 164.476 1.00 77.18  ? 393 ARG B NH2 1 
ATOM   5985 N N   . GLY B 1 394 ? 146.815 185.424 170.508 1.00 77.26  ? 394 GLY B N   1 
ATOM   5986 C CA  . GLY B 1 394 ? 146.618 186.708 171.145 1.00 77.26  ? 394 GLY B CA  1 
ATOM   5987 C C   . GLY B 1 394 ? 147.662 187.085 172.172 1.00 77.26  ? 394 GLY B C   1 
ATOM   5988 O O   . GLY B 1 394 ? 147.584 188.183 172.736 1.00 77.26  ? 394 GLY B O   1 
ATOM   5989 N N   . VAL B 1 395 ? 148.627 186.216 172.435 1.00 75.32  ? 395 VAL B N   1 
ATOM   5990 C CA  . VAL B 1 395 ? 149.686 186.506 173.408 1.00 75.32  ? 395 VAL B CA  1 
ATOM   5991 C C   . VAL B 1 395 ? 150.592 187.602 172.859 1.00 75.32  ? 395 VAL B C   1 
ATOM   5992 O O   . VAL B 1 395 ? 150.910 187.589 171.656 1.00 75.32  ? 395 VAL B O   1 
ATOM   5993 C CB  . VAL B 1 395 ? 150.474 185.230 173.715 1.00 75.32  ? 395 VAL B CB  1 
ATOM   5994 C CG1 . VAL B 1 395 ? 151.779 185.549 174.393 1.00 75.32  ? 395 VAL B CG1 1 
ATOM   5995 C CG2 . VAL B 1 395 ? 149.648 184.311 174.594 1.00 75.32  ? 395 VAL B CG2 1 
ATOM   5996 N N   . PRO B 1 396 ? 151.018 188.565 173.675 1.00 73.63  ? 396 PRO B N   1 
ATOM   5997 C CA  . PRO B 1 396 ? 151.919 189.611 173.181 1.00 73.63  ? 396 PRO B CA  1 
ATOM   5998 C C   . PRO B 1 396 ? 153.286 189.054 172.813 1.00 73.63  ? 396 PRO B C   1 
ATOM   5999 O O   . PRO B 1 396 ? 153.695 187.978 173.252 1.00 73.63  ? 396 PRO B O   1 
ATOM   6000 C CB  . PRO B 1 396 ? 152.017 190.584 174.360 1.00 73.63  ? 396 PRO B CB  1 
ATOM   6001 C CG  . PRO B 1 396 ? 151.638 189.777 175.550 1.00 73.63  ? 396 PRO B CG  1 
ATOM   6002 C CD  . PRO B 1 396 ? 150.621 188.796 175.073 1.00 73.63  ? 396 PRO B CD  1 
ATOM   6003 N N   . TYR B 1 397 ? 153.998 189.819 171.984 1.00 71.19  ? 397 TYR B N   1 
ATOM   6004 C CA  . TYR B 1 397 ? 155.263 189.343 171.433 1.00 71.19  ? 397 TYR B CA  1 
ATOM   6005 C C   . TYR B 1 397 ? 156.355 189.294 172.495 1.00 71.19  ? 397 TYR B C   1 
ATOM   6006 O O   . TYR B 1 397 ? 156.915 188.229 172.775 1.00 71.19  ? 397 TYR B O   1 
ATOM   6007 C CB  . TYR B 1 397 ? 155.694 190.232 170.266 1.00 71.19  ? 397 TYR B CB  1 
ATOM   6008 C CG  . TYR B 1 397 ? 157.109 189.975 169.798 1.00 71.19  ? 397 TYR B CG  1 
ATOM   6009 C CD1 . TYR B 1 397 ? 157.419 188.843 169.060 1.00 71.19  ? 397 TYR B CD1 1 
ATOM   6010 C CD2 . TYR B 1 397 ? 158.133 190.864 170.093 1.00 71.19  ? 397 TYR B CD2 1 
ATOM   6011 C CE1 . TYR B 1 397 ? 158.708 188.602 168.629 1.00 71.19  ? 397 TYR B CE1 1 
ATOM   6012 C CE2 . TYR B 1 397 ? 159.426 190.630 169.666 1.00 71.19  ? 397 TYR B CE2 1 
ATOM   6013 C CZ  . TYR B 1 397 ? 159.706 189.497 168.935 1.00 71.19  ? 397 TYR B CZ  1 
ATOM   6014 O OH  . TYR B 1 397 ? 160.989 189.256 168.507 1.00 71.19  ? 397 TYR B OH  1 
ATOM   6015 N N   . PHE B 1 398 ? 156.672 190.444 173.097 1.00 74.69  ? 398 PHE B N   1 
ATOM   6016 C CA  . PHE B 1 398 ? 157.878 190.548 173.918 1.00 74.69  ? 398 PHE B CA  1 
ATOM   6017 C C   . PHE B 1 398 ? 157.879 189.611 175.120 1.00 74.69  ? 398 PHE B C   1 
ATOM   6018 O O   . PHE B 1 398 ? 158.772 188.750 175.207 1.00 74.69  ? 398 PHE B O   1 
ATOM   6019 C CB  . PHE B 1 398 ? 158.088 192.002 174.346 1.00 74.69  ? 398 PHE B CB  1 
ATOM   6020 C CG  . PHE B 1 398 ? 158.928 192.146 175.583 1.00 74.69  ? 398 PHE B CG  1 
ATOM   6021 C CD1 . PHE B 1 398 ? 160.289 191.890 175.545 1.00 74.69  ? 398 PHE B CD1 1 
ATOM   6022 C CD2 . PHE B 1 398 ? 158.357 192.521 176.786 1.00 74.69  ? 398 PHE B CD2 1 
ATOM   6023 C CE1 . PHE B 1 398 ? 161.065 192.013 176.680 1.00 74.69  ? 398 PHE B CE1 1 
ATOM   6024 C CE2 . PHE B 1 398 ? 159.128 192.645 177.925 1.00 74.69  ? 398 PHE B CE2 1 
ATOM   6025 C CZ  . PHE B 1 398 ? 160.484 192.392 177.871 1.00 74.69  ? 398 PHE B CZ  1 
ATOM   6026 N N   . PRO B 1 399 ? 156.948 189.715 176.075 1.00 74.62  ? 399 PRO B N   1 
ATOM   6027 C CA  . PRO B 1 399 ? 157.123 188.955 177.323 1.00 74.62  ? 399 PRO B CA  1 
ATOM   6028 C C   . PRO B 1 399 ? 157.139 187.449 177.135 1.00 74.62  ? 399 PRO B C   1 
ATOM   6029 O O   . PRO B 1 399 ? 157.840 186.755 177.881 1.00 74.62  ? 399 PRO B O   1 
ATOM   6030 C CB  . PRO B 1 399 ? 155.928 189.402 178.174 1.00 74.62  ? 399 PRO B CB  1 
ATOM   6031 C CG  . PRO B 1 399 ? 154.901 189.786 177.192 1.00 74.62  ? 399 PRO B CG  1 
ATOM   6032 C CD  . PRO B 1 399 ? 155.632 190.379 176.027 1.00 74.62  ? 399 PRO B CD  1 
ATOM   6033 N N   . ASN B 1 400 ? 156.405 186.918 176.157 1.00 72.91  ? 400 ASN B N   1 
ATOM   6034 C CA  . ASN B 1 400 ? 156.188 185.483 176.064 1.00 72.91  ? 400 ASN B CA  1 
ATOM   6035 C C   . ASN B 1 400 ? 156.703 184.842 174.784 1.00 72.91  ? 400 ASN B C   1 
ATOM   6036 O O   . ASN B 1 400 ? 156.499 183.638 174.596 1.00 72.91  ? 400 ASN B O   1 
ATOM   6037 C CB  . ASN B 1 400 ? 154.694 185.168 176.205 1.00 72.91  ? 400 ASN B CB  1 
ATOM   6038 C CG  . ASN B 1 400 ? 154.140 185.553 177.558 1.00 72.91  ? 400 ASN B CG  1 
ATOM   6039 O OD1 . ASN B 1 400 ? 154.522 184.985 178.580 1.00 72.91  ? 400 ASN B OD1 1 
ATOM   6040 N ND2 . ASN B 1 400 ? 153.239 186.527 177.575 1.00 72.91  ? 400 ASN B ND2 1 
ATOM   6041 N N   . LEU B 1 401 ? 157.352 185.591 173.895 1.00 67.63  ? 401 LEU B N   1 
ATOM   6042 C CA  . LEU B 1 401 ? 157.897 185.003 172.678 1.00 67.63  ? 401 LEU B CA  1 
ATOM   6043 C C   . LEU B 1 401 ? 159.403 185.169 172.565 1.00 67.63  ? 401 LEU B C   1 
ATOM   6044 O O   . LEU B 1 401 ? 160.104 184.195 172.275 1.00 67.63  ? 401 LEU B O   1 
ATOM   6045 C CB  . LEU B 1 401 ? 157.214 185.608 171.442 1.00 67.63  ? 401 LEU B CB  1 
ATOM   6046 C CG  . LEU B 1 401 ? 157.351 184.800 170.149 1.00 67.63  ? 401 LEU B CG  1 
ATOM   6047 C CD1 . LEU B 1 401 ? 157.030 183.336 170.388 1.00 67.63  ? 401 LEU B CD1 1 
ATOM   6048 C CD2 . LEU B 1 401 ? 156.465 185.368 169.054 1.00 67.63  ? 401 LEU B CD2 1 
ATOM   6049 N N   . VAL B 1 402 ? 159.925 186.377 172.783 1.00 65.82  ? 402 VAL B N   1 
ATOM   6050 C CA  . VAL B 1 402 ? 161.348 186.607 172.561 1.00 65.82  ? 402 VAL B CA  1 
ATOM   6051 C C   . VAL B 1 402 ? 162.197 185.926 173.630 1.00 65.82  ? 402 VAL B C   1 
ATOM   6052 O O   . VAL B 1 402 ? 163.333 185.520 173.358 1.00 65.82  ? 402 VAL B O   1 
ATOM   6053 C CB  . VAL B 1 402 ? 161.637 188.119 172.469 1.00 65.82  ? 402 VAL B CB  1 
ATOM   6054 C CG1 . VAL B 1 402 ? 161.593 188.769 173.834 1.00 65.82  ? 402 VAL B CG1 1 
ATOM   6055 C CG2 . VAL B 1 402 ? 162.980 188.361 171.810 1.00 65.82  ? 402 VAL B CG2 1 
ATOM   6056 N N   . MET B 1 403 ? 161.681 185.793 174.858 1.00 66.92  ? 403 MET B N   1 
ATOM   6057 C CA  . MET B 1 403 ? 162.479 185.176 175.918 1.00 66.92  ? 403 MET B CA  1 
ATOM   6058 C C   . MET B 1 403 ? 162.755 183.698 175.661 1.00 66.92  ? 403 MET B C   1 
ATOM   6059 O O   . MET B 1 403 ? 163.932 183.294 175.722 1.00 66.92  ? 403 MET B O   1 
ATOM   6060 C CB  . MET B 1 403 ? 161.808 185.406 177.276 1.00 66.92  ? 403 MET B CB  1 
ATOM   6061 C CG  . MET B 1 403 ? 162.040 186.793 177.846 1.00 66.92  ? 403 MET B CG  1 
ATOM   6062 S SD  . MET B 1 403 ? 163.784 187.245 177.853 1.00 66.92  ? 403 MET B SD  1 
ATOM   6063 C CE  . MET B 1 403 ? 163.738 188.796 176.961 1.00 66.92  ? 403 MET B CE  1 
ATOM   6064 N N   . PRO B 1 404 ? 161.758 182.843 175.386 1.00 61.42  ? 404 PRO B N   1 
ATOM   6065 C CA  . PRO B 1 404 ? 162.088 181.440 175.088 1.00 61.42  ? 404 PRO B CA  1 
ATOM   6066 C C   . PRO B 1 404 ? 162.985 181.294 173.878 1.00 61.42  ? 404 PRO B C   1 
ATOM   6067 O O   . PRO B 1 404 ? 163.859 180.421 173.858 1.00 61.42  ? 404 PRO B O   1 
ATOM   6068 C CB  . PRO B 1 404 ? 160.715 180.794 174.855 1.00 61.42  ? 404 PRO B CB  1 
ATOM   6069 C CG  . PRO B 1 404 ? 159.743 181.711 175.470 1.00 61.42  ? 404 PRO B CG  1 
ATOM   6070 C CD  . PRO B 1 404 ? 160.306 183.076 175.309 1.00 61.42  ? 404 PRO B CD  1 
ATOM   6071 N N   . ILE B 1 405 ? 162.799 182.148 172.871 1.00 58.77  ? 405 ILE B N   1 
ATOM   6072 C CA  . ILE B 1 405 ? 163.630 182.092 171.673 1.00 58.77  ? 405 ILE B CA  1 
ATOM   6073 C C   . ILE B 1 405 ? 165.086 182.367 172.025 1.00 58.77  ? 405 ILE B C   1 
ATOM   6074 O O   . ILE B 1 405 ? 165.994 181.646 171.597 1.00 58.77  ? 405 ILE B O   1 
ATOM   6075 C CB  . ILE B 1 405 ? 163.104 183.080 170.617 1.00 58.77  ? 405 ILE B CB  1 
ATOM   6076 C CG1 . ILE B 1 405 ? 161.742 182.623 170.095 1.00 58.77  ? 405 ILE B CG1 1 
ATOM   6077 C CG2 . ILE B 1 405 ? 164.086 183.227 169.483 1.00 58.77  ? 405 ILE B CG2 1 
ATOM   6078 C CD1 . ILE B 1 405 ? 161.810 181.471 169.130 1.00 58.77  ? 405 ILE B CD1 1 
ATOM   6079 N N   . VAL B 1 406 ? 165.328 183.398 172.837 1.00 58.01  ? 406 VAL B N   1 
ATOM   6080 C CA  . VAL B 1 406 ? 166.693 183.756 173.209 1.00 58.01  ? 406 VAL B CA  1 
ATOM   6081 C C   . VAL B 1 406 ? 167.329 182.665 174.064 1.00 58.01  ? 406 VAL B C   1 
ATOM   6082 O O   . VAL B 1 406 ? 168.491 182.289 173.853 1.00 58.01  ? 406 VAL B O   1 
ATOM   6083 C CB  . VAL B 1 406 ? 166.705 185.120 173.922 1.00 58.01  ? 406 VAL B CB  1 
ATOM   6084 C CG1 . VAL B 1 406 ? 167.978 185.294 174.728 1.00 58.01  ? 406 VAL B CG1 1 
ATOM   6085 C CG2 . VAL B 1 406 ? 166.553 186.244 172.913 1.00 58.01  ? 406 VAL B CG2 1 
ATOM   6086 N N   . VAL B 1 407 ? 166.587 182.137 175.042 1.00 56.43  ? 407 VAL B N   1 
ATOM   6087 C CA  . VAL B 1 407 ? 167.152 181.107 175.913 1.00 56.43  ? 407 VAL B CA  1 
ATOM   6088 C C   . VAL B 1 407 ? 167.468 179.843 175.118 1.00 56.43  ? 407 VAL B C   1 
ATOM   6089 O O   . VAL B 1 407 ? 168.543 179.242 175.274 1.00 56.43  ? 407 VAL B O   1 
ATOM   6090 C CB  . VAL B 1 407 ? 166.201 180.823 177.089 1.00 56.43  ? 407 VAL B CB  1 
ATOM   6091 C CG1 . VAL B 1 407 ? 166.754 179.715 177.960 1.00 56.43  ? 407 VAL B CG1 1 
ATOM   6092 C CG2 . VAL B 1 407 ? 165.992 182.081 177.906 1.00 56.43  ? 407 VAL B CG2 1 
ATOM   6093 N N   . GLY B 1 408 ? 166.547 179.422 174.248 1.00 56.73  ? 408 GLY B N   1 
ATOM   6094 C CA  . GLY B 1 408 ? 166.805 178.257 173.421 1.00 56.73  ? 408 GLY B CA  1 
ATOM   6095 C C   . GLY B 1 408 ? 167.951 178.469 172.453 1.00 56.73  ? 408 GLY B C   1 
ATOM   6096 O O   . GLY B 1 408 ? 168.714 177.544 172.171 1.00 56.73  ? 408 GLY B O   1 
ATOM   6097 N N   . GLY B 1 409 ? 168.089 179.688 171.927 1.00 55.94  ? 409 GLY B N   1 
ATOM   6098 C CA  . GLY B 1 409 ? 169.217 179.981 171.063 1.00 55.94  ? 409 GLY B CA  1 
ATOM   6099 C C   . GLY B 1 409 ? 170.542 179.882 171.791 1.00 55.94  ? 409 GLY B C   1 
ATOM   6100 O O   . GLY B 1 409 ? 171.511 179.335 171.261 1.00 55.94  ? 409 GLY B O   1 
ATOM   6101 N N   . ILE B 1 410 ? 170.600 180.405 173.019 1.00 54.71  ? 410 ILE B N   1 
ATOM   6102 C CA  . ILE B 1 410 ? 171.820 180.277 173.813 1.00 54.71  ? 410 ILE B CA  1 
ATOM   6103 C C   . ILE B 1 410 ? 172.139 178.809 174.066 1.00 54.71  ? 410 ILE B C   1 
ATOM   6104 O O   . ILE B 1 410 ? 173.291 178.377 173.931 1.00 54.71  ? 410 ILE B O   1 
ATOM   6105 C CB  . ILE B 1 410 ? 171.698 181.065 175.131 1.00 54.71  ? 410 ILE B CB  1 
ATOM   6106 C CG1 . ILE B 1 410 ? 171.677 182.568 174.859 1.00 54.71  ? 410 ILE B CG1 1 
ATOM   6107 C CG2 . ILE B 1 410 ? 172.844 180.730 176.063 1.00 54.71  ? 410 ILE B CG2 1 
ATOM   6108 C CD1 . ILE B 1 410 ? 171.417 183.402 176.089 1.00 54.71  ? 410 ILE B CD1 1 
ATOM   6109 N N   . GLY B 1 411 ? 171.126 178.017 174.422 1.00 55.65  ? 411 GLY B N   1 
ATOM   6110 C CA  . GLY B 1 411 ? 171.364 176.600 174.661 1.00 55.65  ? 411 GLY B CA  1 
ATOM   6111 C C   . GLY B 1 411 ? 171.855 175.863 173.427 1.00 55.65  ? 411 GLY B C   1 
ATOM   6112 O O   . GLY B 1 411 ? 172.805 175.075 173.496 1.00 55.65  ? 411 GLY B O   1 
ATOM   6113 N N   . ILE B 1 412 ? 171.221 176.113 172.280 1.00 55.55  ? 412 ILE B N   1 
ATOM   6114 C CA  . ILE B 1 412 ? 171.625 175.459 171.039 1.00 55.55  ? 412 ILE B CA  1 
ATOM   6115 C C   . ILE B 1 412 ? 173.045 175.859 170.663 1.00 55.55  ? 412 ILE B C   1 
ATOM   6116 O O   . ILE B 1 412 ? 173.851 175.019 170.243 1.00 55.55  ? 412 ILE B O   1 
ATOM   6117 C CB  . ILE B 1 412 ? 170.627 175.790 169.914 1.00 55.55  ? 412 ILE B CB  1 
ATOM   6118 C CG1 . ILE B 1 412 ? 169.305 175.058 170.140 1.00 55.55  ? 412 ILE B CG1 1 
ATOM   6119 C CG2 . ILE B 1 412 ? 171.202 175.425 168.560 1.00 55.55  ? 412 ILE B CG2 1 
ATOM   6120 C CD1 . ILE B 1 412 ? 168.148 175.651 169.376 1.00 55.55  ? 412 ILE B CD1 1 
ATOM   6121 N N   . GLY B 1 413 ? 173.372 177.145 170.792 1.00 52.76  ? 413 GLY B N   1 
ATOM   6122 C CA  . GLY B 1 413 ? 174.724 177.581 170.493 1.00 52.76  ? 413 GLY B CA  1 
ATOM   6123 C C   . GLY B 1 413 ? 175.754 176.942 171.402 1.00 52.76  ? 413 GLY B C   1 
ATOM   6124 O O   . GLY B 1 413 ? 176.843 176.575 170.958 1.00 52.76  ? 413 GLY B O   1 
ATOM   6125 N N   . MET B 1 414 ? 175.422 176.795 172.686 1.00 56.84  ? 414 MET B N   1 
ATOM   6126 C CA  . MET B 1 414 ? 176.357 176.163 173.610 1.00 56.84  ? 414 MET B CA  1 
ATOM   6127 C C   . MET B 1 414 ? 176.530 174.681 173.312 1.00 56.84  ? 414 MET B C   1 
ATOM   6128 O O   . MET B 1 414 ? 177.609 174.128 173.548 1.00 56.84  ? 414 MET B O   1 
ATOM   6129 C CB  . MET B 1 414 ? 175.892 176.358 175.052 1.00 56.84  ? 414 MET B CB  1 
ATOM   6130 C CG  . MET B 1 414 ? 176.130 177.754 175.596 1.00 56.84  ? 414 MET B CG  1 
ATOM   6131 S SD  . MET B 1 414 ? 176.164 177.807 177.394 1.00 56.84  ? 414 MET B SD  1 
ATOM   6132 C CE  . MET B 1 414 ? 177.035 176.287 177.755 1.00 56.84  ? 414 MET B CE  1 
ATOM   6133 N N   . ALA B 1 415 ? 175.490 174.020 172.803 1.00 53.35  ? 415 ALA B N   1 
ATOM   6134 C CA  . ALA B 1 415 ? 175.572 172.585 172.559 1.00 53.35  ? 415 ALA B CA  1 
ATOM   6135 C C   . ALA B 1 415 ? 176.140 172.217 171.192 1.00 53.35  ? 415 ALA B C   1 
ATOM   6136 O O   . ALA B 1 415 ? 176.635 171.097 171.034 1.00 53.35  ? 415 ALA B O   1 
ATOM   6137 C CB  . ALA B 1 415 ? 174.192 171.943 172.710 1.00 53.35  ? 415 ALA B CB  1 
ATOM   6138 N N   . VAL B 1 416 ? 176.075 173.112 170.203 1.00 52.01  ? 416 VAL B N   1 
ATOM   6139 C CA  . VAL B 1 416 ? 176.465 172.734 168.844 1.00 52.01  ? 416 VAL B CA  1 
ATOM   6140 C C   . VAL B 1 416 ? 177.974 172.535 168.726 1.00 52.01  ? 416 VAL B C   1 
ATOM   6141 O O   . VAL B 1 416 ? 178.434 171.573 168.101 1.00 52.01  ? 416 VAL B O   1 
ATOM   6142 C CB  . VAL B 1 416 ? 175.950 173.771 167.828 1.00 52.01  ? 416 VAL B CB  1 
ATOM   6143 C CG1 . VAL B 1 416 ? 176.707 173.654 166.522 1.00 52.01  ? 416 VAL B CG1 1 
ATOM   6144 C CG2 . VAL B 1 416 ? 174.472 173.564 167.573 1.00 52.01  ? 416 VAL B CG2 1 
ATOM   6145 N N   . VAL B 1 417 ? 178.769 173.437 169.309 1.00 50.35  ? 417 VAL B N   1 
ATOM   6146 C CA  . VAL B 1 417 ? 180.219 173.408 169.081 1.00 50.35  ? 417 VAL B CA  1 
ATOM   6147 C C   . VAL B 1 417 ? 180.869 172.108 169.550 1.00 50.35  ? 417 VAL B C   1 
ATOM   6148 O O   . VAL B 1 417 ? 181.672 171.540 168.792 1.00 50.35  ? 417 VAL B O   1 
ATOM   6149 C CB  . VAL B 1 417 ? 180.879 174.650 169.702 1.00 50.35  ? 417 VAL B CB  1 
ATOM   6150 C CG1 . VAL B 1 417 ? 182.340 174.725 169.300 1.00 50.35  ? 417 VAL B CG1 1 
ATOM   6151 C CG2 . VAL B 1 417 ? 180.150 175.903 169.279 1.00 50.35  ? 417 VAL B CG2 1 
ATOM   6152 N N   . PRO B 1 418 ? 180.610 171.605 170.767 1.00 52.07  ? 418 PRO B N   1 
ATOM   6153 C CA  . PRO B 1 418 ? 181.251 170.338 171.162 1.00 52.07  ? 418 PRO B CA  1 
ATOM   6154 C C   . PRO B 1 418 ? 180.916 169.170 170.250 1.00 52.07  ? 418 PRO B C   1 
ATOM   6155 O O   . PRO B 1 418 ? 181.784 168.329 169.992 1.00 52.07  ? 418 PRO B O   1 
ATOM   6156 C CB  . PRO B 1 418 ? 180.735 170.115 172.591 1.00 52.07  ? 418 PRO B CB  1 
ATOM   6157 C CG  . PRO B 1 418 ? 179.556 171.000 172.729 1.00 52.07  ? 418 PRO B CG  1 
ATOM   6158 C CD  . PRO B 1 418 ? 179.850 172.185 171.887 1.00 52.07  ? 418 PRO B CD  1 
ATOM   6159 N N   . LEU B 1 419 ? 179.683 169.095 169.745 1.00 51.84  ? 419 LEU B N   1 
ATOM   6160 C CA  . LEU B 1 419 ? 179.323 168.013 168.833 1.00 51.84  ? 419 LEU B CA  1 
ATOM   6161 C C   . LEU B 1 419 ? 180.099 168.106 167.525 1.00 51.84  ? 419 LEU B C   1 
ATOM   6162 O O   . LEU B 1 419 ? 180.587 167.091 167.012 1.00 51.84  ? 419 LEU B O   1 
ATOM   6163 C CB  . LEU B 1 419 ? 177.819 168.033 168.567 1.00 51.84  ? 419 LEU B CB  1 
ATOM   6164 C CG  . LEU B 1 419 ? 176.934 167.359 169.614 1.00 51.84  ? 419 LEU B CG  1 
ATOM   6165 C CD1 . LEU B 1 419 ? 175.473 167.681 169.362 1.00 51.84  ? 419 LEU B CD1 1 
ATOM   6166 C CD2 . LEU B 1 419 ? 177.156 165.859 169.611 1.00 51.84  ? 419 LEU B CD2 1 
ATOM   6167 N N   . THR B 1 420 ? 180.225 169.314 166.970 1.00 51.50  ? 420 THR B N   1 
ATOM   6168 C CA  . THR B 1 420 ? 180.985 169.485 165.736 1.00 51.50  ? 420 THR B CA  1 
ATOM   6169 C C   . THR B 1 420 ? 182.456 169.158 165.948 1.00 51.50  ? 420 THR B C   1 
ATOM   6170 O O   . THR B 1 420 ? 183.097 168.563 165.076 1.00 51.50  ? 420 THR B O   1 
ATOM   6171 C CB  . THR B 1 420 ? 180.825 170.910 165.210 1.00 51.50  ? 420 THR B CB  1 
ATOM   6172 O OG1 . THR B 1 420 ? 179.449 171.299 165.291 1.00 51.50  ? 420 THR B OG1 1 
ATOM   6173 C CG2 . THR B 1 420 ? 181.280 170.996 163.767 1.00 51.50  ? 420 THR B CG2 1 
ATOM   6174 N N   . LEU B 1 421 ? 183.012 169.546 167.097 1.00 51.03  ? 421 LEU B N   1 
ATOM   6175 C CA  . LEU B 1 421 ? 184.401 169.208 167.386 1.00 51.03  ? 421 LEU B CA  1 
ATOM   6176 C C   . LEU B 1 421 ? 184.591 167.706 167.562 1.00 51.03  ? 421 LEU B C   1 
ATOM   6177 O O   . LEU B 1 421 ? 185.625 167.164 167.160 1.00 51.03  ? 421 LEU B O   1 
ATOM   6178 C CB  . LEU B 1 421 ? 184.878 169.953 168.631 1.00 51.03  ? 421 LEU B CB  1 
ATOM   6179 C CG  . LEU B 1 421 ? 185.269 171.415 168.426 1.00 51.03  ? 421 LEU B CG  1 
ATOM   6180 C CD1 . LEU B 1 421 ? 185.670 172.044 169.744 1.00 51.03  ? 421 LEU B CD1 1 
ATOM   6181 C CD2 . LEU B 1 421 ? 186.390 171.531 167.416 1.00 51.03  ? 421 LEU B CD2 1 
ATOM   6182 N N   . SER B 1 422 ? 183.614 167.023 168.162 1.00 52.90  ? 422 SER B N   1 
ATOM   6183 C CA  . SER B 1 422 ? 183.719 165.579 168.339 1.00 52.90  ? 422 SER B CA  1 
ATOM   6184 C C   . SER B 1 422 ? 183.535 164.831 167.025 1.00 52.90  ? 422 SER B C   1 
ATOM   6185 O O   . SER B 1 422 ? 184.049 163.718 166.872 1.00 52.90  ? 422 SER B O   1 
ATOM   6186 C CB  . SER B 1 422 ? 182.688 165.100 169.359 1.00 52.90  ? 422 SER B CB  1 
ATOM   6187 O OG  . SER B 1 422 ? 182.749 165.870 170.544 1.00 52.90  ? 422 SER B OG  1 
ATOM   6188 N N   . ALA B 1 423 ? 182.803 165.414 166.074 1.00 52.56  ? 423 ALA B N   1 
ATOM   6189 C CA  . ALA B 1 423 ? 182.528 164.722 164.820 1.00 52.56  ? 423 ALA B CA  1 
ATOM   6190 C C   . ALA B 1 423 ? 183.763 164.551 163.944 1.00 52.56  ? 423 ALA B C   1 
ATOM   6191 O O   . ALA B 1 423 ? 183.792 163.633 163.120 1.00 52.56  ? 423 ALA B O   1 
ATOM   6192 C CB  . ALA B 1 423 ? 181.447 165.466 164.038 1.00 52.56  ? 423 ALA B CB  1 
ATOM   6193 N N   . ILE B 1 424 ? 184.777 165.402 164.094 1.00 53.42  ? 424 ILE B N   1 
ATOM   6194 C CA  . ILE B 1 424 ? 185.923 165.383 163.189 1.00 53.42  ? 424 ILE B CA  1 
ATOM   6195 C C   . ILE B 1 424 ? 187.215 165.119 163.951 1.00 53.42  ? 424 ILE B C   1 
ATOM   6196 O O   . ILE B 1 424 ? 188.290 165.567 163.539 1.00 53.42  ? 424 ILE B O   1 
ATOM   6197 C CB  . ILE B 1 424 ? 186.024 166.700 162.398 1.00 53.42  ? 424 ILE B CB  1 
ATOM   6198 C CG1 . ILE B 1 424 ? 186.107 167.893 163.352 1.00 53.42  ? 424 ILE B CG1 1 
ATOM   6199 C CG2 . ILE B 1 424 ? 184.843 166.847 161.453 1.00 53.42  ? 424 ILE B CG2 1 
ATOM   6200 C CD1 . ILE B 1 424 ? 186.141 169.232 162.658 1.00 53.42  ? 424 ILE B CD1 1 
ATOM   6201 N N   . ALA B 1 425 ? 187.127 164.377 165.050 1.00 57.98  ? 425 ALA B N   1 
ATOM   6202 C CA  . ALA B 1 425 ? 188.267 164.142 165.925 1.00 57.98  ? 425 ALA B CA  1 
ATOM   6203 C C   . ALA B 1 425 ? 188.928 162.811 165.592 1.00 57.98  ? 425 ALA B C   1 
ATOM   6204 O O   . ALA B 1 425 ? 188.250 161.783 165.490 1.00 57.98  ? 425 ALA B O   1 
ATOM   6205 C CB  . ALA B 1 425 ? 187.837 164.160 167.391 1.00 57.98  ? 425 ALA B CB  1 
ATOM   6206 N N   . GLY B 1 426 ? 190.249 162.836 165.429 1.00 62.60  ? 426 GLY B N   1 
ATOM   6207 C CA  . GLY B 1 426 ? 191.031 161.627 165.255 1.00 62.60  ? 426 GLY B CA  1 
ATOM   6208 C C   . GLY B 1 426 ? 190.738 160.832 164.000 1.00 62.60  ? 426 GLY B C   1 
ATOM   6209 O O   . GLY B 1 426 ? 190.592 159.608 164.061 1.00 62.60  ? 426 GLY B O   1 
ATOM   6210 N N   . VAL B 1 427 ? 190.656 161.507 162.854 1.00 64.05  ? 427 VAL B N   1 
ATOM   6211 C CA  . VAL B 1 427 ? 190.362 160.842 161.597 1.00 64.05  ? 427 VAL B CA  1 
ATOM   6212 C C   . VAL B 1 427 ? 191.579 160.743 160.683 1.00 64.05  ? 427 VAL B C   1 
ATOM   6213 O O   . VAL B 1 427 ? 191.708 159.754 159.953 1.00 64.05  ? 427 VAL B O   1 
ATOM   6214 C CB  . VAL B 1 427 ? 189.198 161.541 160.868 1.00 64.05  ? 427 VAL B CB  1 
ATOM   6215 C CG1 . VAL B 1 427 ? 187.884 161.215 161.542 1.00 64.05  ? 427 VAL B CG1 1 
ATOM   6216 C CG2 . VAL B 1 427 ? 189.423 163.037 160.839 1.00 64.05  ? 427 VAL B CG2 1 
ATOM   6217 N N   . GLY B 1 428 ? 192.472 161.728 160.698 1.00 67.65  ? 428 GLY B N   1 
ATOM   6218 C CA  . GLY B 1 428 ? 193.572 161.775 159.760 1.00 67.65  ? 428 GLY B CA  1 
ATOM   6219 C C   . GLY B 1 428 ? 193.183 162.457 158.461 1.00 67.65  ? 428 GLY B C   1 
ATOM   6220 O O   . GLY B 1 428 ? 192.024 162.795 158.213 1.00 67.65  ? 428 GLY B O   1 
ATOM   6221 N N   . PHE B 1 429 ? 194.186 162.666 157.611 1.00 68.94  ? 429 PHE B N   1 
ATOM   6222 C CA  . PHE B 1 429 ? 193.956 163.352 156.346 1.00 68.94  ? 429 PHE B CA  1 
ATOM   6223 C C   . PHE B 1 429 ? 193.502 162.419 155.234 1.00 68.94  ? 429 PHE B C   1 
ATOM   6224 O O   . PHE B 1 429 ? 193.230 162.892 154.126 1.00 68.94  ? 429 PHE B O   1 
ATOM   6225 C CB  . PHE B 1 429 ? 195.221 164.091 155.909 1.00 68.94  ? 429 PHE B CB  1 
ATOM   6226 C CG  . PHE B 1 429 ? 195.299 165.505 156.407 1.00 68.94  ? 429 PHE B CG  1 
ATOM   6227 C CD1 . PHE B 1 429 ? 195.798 166.511 155.599 1.00 68.94  ? 429 PHE B CD1 1 
ATOM   6228 C CD2 . PHE B 1 429 ? 194.870 165.828 157.683 1.00 68.94  ? 429 PHE B CD2 1 
ATOM   6229 C CE1 . PHE B 1 429 ? 195.871 167.812 156.056 1.00 68.94  ? 429 PHE B CE1 1 
ATOM   6230 C CE2 . PHE B 1 429 ? 194.940 167.126 158.145 1.00 68.94  ? 429 PHE B CE2 1 
ATOM   6231 C CZ  . PHE B 1 429 ? 195.441 168.119 157.330 1.00 68.94  ? 429 PHE B CZ  1 
ATOM   6232 N N   . ASP B 1 430 ? 193.415 161.116 155.495 1.00 70.29  ? 430 ASP B N   1 
ATOM   6233 C CA  . ASP B 1 430 ? 192.968 160.167 154.486 1.00 70.29  ? 430 ASP B CA  1 
ATOM   6234 C C   . ASP B 1 430 ? 191.492 159.818 154.603 1.00 70.29  ? 430 ASP B C   1 
ATOM   6235 O O   . ASP B 1 430 ? 190.904 159.352 153.622 1.00 70.29  ? 430 ASP B O   1 
ATOM   6236 C CB  . ASP B 1 430 ? 193.792 158.879 154.565 1.00 70.29  ? 430 ASP B CB  1 
ATOM   6237 C CG  . ASP B 1 430 ? 195.275 159.146 154.695 1.00 70.29  ? 430 ASP B CG  1 
ATOM   6238 O OD1 . ASP B 1 430 ? 195.808 159.016 155.817 1.00 70.29  ? 430 ASP B OD1 1 
ATOM   6239 O OD2 . ASP B 1 430 ? 195.910 159.483 153.674 1.00 70.29  ? 430 ASP B OD2 1 
ATOM   6240 N N   . GLN B 1 431 ? 190.880 160.026 155.771 1.00 64.82  ? 431 GLN B N   1 
ATOM   6241 C CA  . GLN B 1 431 ? 189.474 159.692 155.965 1.00 64.82  ? 431 GLN B CA  1 
ATOM   6242 C C   . GLN B 1 431 ? 188.655 160.889 156.434 1.00 64.82  ? 431 GLN B C   1 
ATOM   6243 O O   . GLN B 1 431 ? 187.511 160.714 156.859 1.00 64.82  ? 431 GLN B O   1 
ATOM   6244 C CB  . GLN B 1 431 ? 189.313 158.541 156.961 1.00 64.82  ? 431 GLN B CB  1 
ATOM   6245 C CG  . GLN B 1 431 ? 189.854 157.202 156.494 1.00 64.82  ? 431 GLN B CG  1 
ATOM   6246 C CD  . GLN B 1 431 ? 191.347 157.073 156.698 1.00 64.82  ? 431 GLN B CD  1 
ATOM   6247 O OE1 . GLN B 1 431 ? 191.947 157.827 157.463 1.00 64.82  ? 431 GLN B OE1 1 
ATOM   6248 N NE2 . GLN B 1 431 ? 191.956 156.110 156.017 1.00 64.82  ? 431 GLN B NE2 1 
ATOM   6249 N N   . ILE B 1 432 ? 189.210 162.100 156.370 1.00 57.67  ? 432 ILE B N   1 
ATOM   6250 C CA  . ILE B 1 432 ? 188.463 163.268 156.824 1.00 57.67  ? 432 ILE B CA  1 
ATOM   6251 C C   . ILE B 1 432 ? 187.301 163.563 155.882 1.00 57.67  ? 432 ILE B C   1 
ATOM   6252 O O   . ILE B 1 432 ? 186.212 163.954 156.321 1.00 57.67  ? 432 ILE B O   1 
ATOM   6253 C CB  . ILE B 1 432 ? 189.401 164.479 156.981 1.00 57.67  ? 432 ILE B CB  1 
ATOM   6254 C CG1 . ILE B 1 432 ? 188.612 165.717 157.406 1.00 57.67  ? 432 ILE B CG1 1 
ATOM   6255 C CG2 . ILE B 1 432 ? 190.169 164.740 155.700 1.00 57.67  ? 432 ILE B CG2 1 
ATOM   6256 C CD1 . ILE B 1 432 ? 187.814 165.523 158.672 1.00 57.67  ? 432 ILE B CD1 1 
ATOM   6257 N N   . GLY B 1 433 ? 187.504 163.372 154.581 1.00 57.01  ? 433 GLY B N   1 
ATOM   6258 C CA  . GLY B 1 433 ? 186.477 163.628 153.601 1.00 57.01  ? 433 GLY B CA  1 
ATOM   6259 C C   . GLY B 1 433 ? 185.237 162.773 153.778 1.00 57.01  ? 433 GLY B C   1 
ATOM   6260 O O   . GLY B 1 433 ? 184.118 163.286 153.901 1.00 57.01  ? 433 GLY B O   1 
ATOM   6261 N N   . PRO B 1 434 ? 185.407 161.447 153.759 1.00 56.06  ? 434 PRO B N   1 
ATOM   6262 C CA  . PRO B 1 434 ? 184.254 160.566 154.006 1.00 56.06  ? 434 PRO B CA  1 
ATOM   6263 C C   . PRO B 1 434 ? 183.600 160.780 155.357 1.00 56.06  ? 434 PRO B C   1 
ATOM   6264 O O   . PRO B 1 434 ? 182.373 160.688 155.460 1.00 56.06  ? 434 PRO B O   1 
ATOM   6265 C CB  . PRO B 1 434 ? 184.862 159.165 153.887 1.00 56.06  ? 434 PRO B CB  1 
ATOM   6266 C CG  . PRO B 1 434 ? 186.006 159.344 152.983 1.00 56.06  ? 434 PRO B CG  1 
ATOM   6267 C CD  . PRO B 1 434 ? 186.576 160.691 153.281 1.00 56.06  ? 434 PRO B CD  1 
ATOM   6268 N N   . VAL B 1 435 ? 184.381 161.063 156.400 1.00 53.91  ? 435 VAL B N   1 
ATOM   6269 C CA  . VAL B 1 435 ? 183.799 161.289 157.719 1.00 53.91  ? 435 VAL B CA  1 
ATOM   6270 C C   . VAL B 1 435 ? 182.929 162.540 157.713 1.00 53.91  ? 435 VAL B C   1 
ATOM   6271 O O   . VAL B 1 435 ? 181.811 162.539 158.245 1.00 53.91  ? 435 VAL B O   1 
ATOM   6272 C CB  . VAL B 1 435 ? 184.908 161.365 158.782 1.00 53.91  ? 435 VAL B CB  1 
ATOM   6273 C CG1 . VAL B 1 435 ? 184.401 162.051 160.034 1.00 53.91  ? 435 VAL B CG1 1 
ATOM   6274 C CG2 . VAL B 1 435 ? 185.408 159.974 159.110 1.00 53.91  ? 435 VAL B CG2 1 
ATOM   6275 N N   . SER B 1 436 ? 183.420 163.622 157.105 1.00 52.75  ? 436 SER B N   1 
ATOM   6276 C CA  . SER B 1 436 ? 182.623 164.839 157.005 1.00 52.75  ? 436 SER B CA  1 
ATOM   6277 C C   . SER B 1 436 ? 181.364 164.609 156.180 1.00 52.75  ? 436 SER B C   1 
ATOM   6278 O O   . SER B 1 436 ? 180.279 165.087 156.539 1.00 52.75  ? 436 SER B O   1 
ATOM   6279 C CB  . SER B 1 436 ? 183.463 165.959 156.398 1.00 52.75  ? 436 SER B CB  1 
ATOM   6280 O OG  . SER B 1 436 ? 184.730 166.025 157.022 1.00 52.75  ? 436 SER B OG  1 
ATOM   6281 N N   . ALA B 1 437 ? 181.487 163.874 155.073 1.00 53.57  ? 437 ALA B N   1 
ATOM   6282 C CA  . ALA B 1 437 ? 180.322 163.595 154.240 1.00 53.57  ? 437 ALA B CA  1 
ATOM   6283 C C   . ALA B 1 437 ? 179.280 162.789 155.002 1.00 53.57  ? 437 ALA B C   1 
ATOM   6284 O O   . ALA B 1 437 ? 178.083 163.082 154.924 1.00 53.57  ? 437 ALA B O   1 
ATOM   6285 C CB  . ALA B 1 437 ? 180.748 162.859 152.973 1.00 53.57  ? 437 ALA B CB  1 
ATOM   6286 N N   . ILE B 1 438 ? 179.716 161.775 155.752 1.00 54.01  ? 438 ILE B N   1 
ATOM   6287 C CA  . ILE B 1 438 ? 178.785 160.949 156.513 1.00 54.01  ? 438 ILE B CA  1 
ATOM   6288 C C   . ILE B 1 438 ? 178.111 161.766 157.606 1.00 54.01  ? 438 ILE B C   1 
ATOM   6289 O O   . ILE B 1 438 ? 176.903 161.635 157.838 1.00 54.01  ? 438 ILE B O   1 
ATOM   6290 C CB  . ILE B 1 438 ? 179.510 159.718 157.086 1.00 54.01  ? 438 ILE B CB  1 
ATOM   6291 C CG1 . ILE B 1 438 ? 179.860 158.739 155.968 1.00 54.01  ? 438 ILE B CG1 1 
ATOM   6292 C CG2 . ILE B 1 438 ? 178.650 159.023 158.118 1.00 54.01  ? 438 ILE B CG2 1 
ATOM   6293 C CD1 . ILE B 1 438 ? 180.975 157.792 156.324 1.00 54.01  ? 438 ILE B CD1 1 
ATOM   6294 N N   . ALA B 1 439 ? 178.872 162.614 158.302 1.00 54.83  ? 439 ALA B N   1 
ATOM   6295 C CA  . ALA B 1 439 ? 178.284 163.436 159.356 1.00 54.83  ? 439 ALA B CA  1 
ATOM   6296 C C   . ALA B 1 439 ? 177.233 164.384 158.792 1.00 54.83  ? 439 ALA B C   1 
ATOM   6297 O O   . ALA B 1 439 ? 176.132 164.515 159.345 1.00 54.83  ? 439 ALA B O   1 
ATOM   6298 C CB  . ALA B 1 439 ? 179.378 164.214 160.084 1.00 54.83  ? 439 ALA B CB  1 
ATOM   6299 N N   . LEU B 1 440 ? 177.551 165.047 157.678 1.00 56.42  ? 440 LEU B N   1 
ATOM   6300 C CA  . LEU B 1 440 ? 176.593 165.963 157.068 1.00 56.42  ? 440 LEU B CA  1 
ATOM   6301 C C   . LEU B 1 440 ? 175.364 165.219 156.559 1.00 56.42  ? 440 LEU B C   1 
ATOM   6302 O O   . LEU B 1 440 ? 174.235 165.709 156.688 1.00 56.42  ? 440 LEU B O   1 
ATOM   6303 C CB  . LEU B 1 440 ? 177.265 166.738 155.937 1.00 56.42  ? 440 LEU B CB  1 
ATOM   6304 C CG  . LEU B 1 440 ? 176.669 168.098 155.582 1.00 56.42  ? 440 LEU B CG  1 
ATOM   6305 C CD1 . LEU B 1 440 ? 176.886 169.084 156.715 1.00 56.42  ? 440 LEU B CD1 1 
ATOM   6306 C CD2 . LEU B 1 440 ? 177.278 168.617 154.298 1.00 56.42  ? 440 LEU B CD2 1 
ATOM   6307 N N   . MET B 1 441 ? 175.563 164.032 155.981 1.00 58.28  ? 441 MET B N   1 
ATOM   6308 C CA  . MET B 1 441 ? 174.439 163.240 155.498 1.00 58.28  ? 441 MET B CA  1 
ATOM   6309 C C   . MET B 1 441 ? 173.527 162.821 156.639 1.00 58.28  ? 441 MET B C   1 
ATOM   6310 O O   . MET B 1 441 ? 172.301 162.874 156.509 1.00 58.28  ? 441 MET B O   1 
ATOM   6311 C CB  . MET B 1 441 ? 174.954 162.016 154.743 1.00 58.28  ? 441 MET B CB  1 
ATOM   6312 C CG  . MET B 1 441 ? 173.873 161.055 154.300 1.00 58.28  ? 441 MET B CG  1 
ATOM   6313 S SD  . MET B 1 441 ? 174.493 159.841 153.125 1.00 58.28  ? 441 MET B SD  1 
ATOM   6314 C CE  . MET B 1 441 ? 174.420 160.779 151.603 1.00 58.28  ? 441 MET B CE  1 
ATOM   6315 N N   . LEU B 1 442 ? 174.103 162.397 157.765 1.00 55.60  ? 442 LEU B N   1 
ATOM   6316 C CA  . LEU B 1 442 ? 173.285 162.022 158.915 1.00 55.60  ? 442 LEU B CA  1 
ATOM   6317 C C   . LEU B 1 442 ? 172.515 163.219 159.455 1.00 55.60  ? 442 LEU B C   1 
ATOM   6318 O O   . LEU B 1 442 ? 171.327 163.107 159.786 1.00 55.60  ? 442 LEU B O   1 
ATOM   6319 C CB  . LEU B 1 442 ? 174.160 161.414 160.008 1.00 55.60  ? 442 LEU B CB  1 
ATOM   6320 C CG  . LEU B 1 442 ? 174.572 159.954 159.841 1.00 55.60  ? 442 LEU B CG  1 
ATOM   6321 C CD1 . LEU B 1 442 ? 175.510 159.554 160.956 1.00 55.60  ? 442 LEU B CD1 1 
ATOM   6322 C CD2 . LEU B 1 442 ? 173.359 159.048 159.817 1.00 55.60  ? 442 LEU B CD2 1 
ATOM   6323 N N   . GLN B 1 443 ? 173.175 164.376 159.546 1.00 58.45  ? 443 GLN B N   1 
ATOM   6324 C CA  . GLN B 1 443 ? 172.498 165.569 160.043 1.00 58.45  ? 443 GLN B CA  1 
ATOM   6325 C C   . GLN B 1 443 ? 171.337 165.963 159.137 1.00 58.45  ? 443 GLN B C   1 
ATOM   6326 O O   . GLN B 1 443 ? 170.268 166.351 159.619 1.00 58.45  ? 443 GLN B O   1 
ATOM   6327 C CB  . GLN B 1 443 ? 173.494 166.720 160.175 1.00 58.45  ? 443 GLN B CB  1 
ATOM   6328 C CG  . GLN B 1 443 ? 172.974 167.904 160.964 1.00 58.45  ? 443 GLN B CG  1 
ATOM   6329 C CD  . GLN B 1 443 ? 172.710 169.112 160.093 1.00 58.45  ? 443 GLN B CD  1 
ATOM   6330 O OE1 . GLN B 1 443 ? 173.312 169.270 159.033 1.00 58.45  ? 443 GLN B OE1 1 
ATOM   6331 N NE2 . GLN B 1 443 ? 171.807 169.974 160.538 1.00 58.45  ? 443 GLN B NE2 1 
ATOM   6332 N N   . SER B 1 444 ? 171.528 165.870 157.818 1.00 58.54  ? 444 SER B N   1 
ATOM   6333 C CA  . SER B 1 444 ? 170.462 166.246 156.895 1.00 58.54  ? 444 SER B CA  1 
ATOM   6334 C C   . SER B 1 444 ? 169.355 165.200 156.844 1.00 58.54  ? 444 SER B C   1 
ATOM   6335 O O   . SER B 1 444 ? 168.193 165.543 156.602 1.00 58.54  ? 444 SER B O   1 
ATOM   6336 C CB  . SER B 1 444 ? 171.038 166.476 155.501 1.00 58.54  ? 444 SER B CB  1 
ATOM   6337 O OG  . SER B 1 444 ? 172.161 167.336 155.557 1.00 58.54  ? 444 SER B OG  1 
ATOM   6338 N N   . LEU B 1 445 ? 169.690 163.928 157.059 1.00 58.66  ? 445 LEU B N   1 
ATOM   6339 C CA  . LEU B 1 445 ? 168.700 162.861 157.010 1.00 58.66  ? 445 LEU B CA  1 
ATOM   6340 C C   . LEU B 1 445 ? 167.837 162.811 158.263 1.00 58.66  ? 445 LEU B C   1 
ATOM   6341 O O   . LEU B 1 445 ? 166.658 162.450 158.180 1.00 58.66  ? 445 LEU B O   1 
ATOM   6342 C CB  . LEU B 1 445 ? 169.403 161.519 156.801 1.00 58.66  ? 445 LEU B CB  1 
ATOM   6343 C CG  . LEU B 1 445 ? 168.601 160.231 156.985 1.00 58.66  ? 445 LEU B CG  1 
ATOM   6344 C CD1 . LEU B 1 445 ? 167.825 159.895 155.725 1.00 58.66  ? 445 LEU B CD1 1 
ATOM   6345 C CD2 . LEU B 1 445 ? 169.524 159.091 157.372 1.00 58.66  ? 445 LEU B CD2 1 
ATOM   6346 N N   . GLY B 1 446 ? 168.394 163.165 159.423 1.00 58.00  ? 446 GLY B N   1 
ATOM   6347 C CA  . GLY B 1 446 ? 167.645 163.050 160.663 1.00 58.00  ? 446 GLY B CA  1 
ATOM   6348 C C   . GLY B 1 446 ? 166.409 163.923 160.740 1.00 58.00  ? 446 GLY B C   1 
ATOM   6349 O O   . GLY B 1 446 ? 165.476 163.592 161.476 1.00 58.00  ? 446 GLY B O   1 
ATOM   6350 N N   . GLY B 1 447 ? 166.375 165.024 159.994 1.00 57.96  ? 447 GLY B N   1 
ATOM   6351 C CA  . GLY B 1 447 ? 165.306 165.992 160.088 1.00 57.96  ? 447 GLY B CA  1 
ATOM   6352 C C   . GLY B 1 447 ? 163.929 165.475 159.715 1.00 57.96  ? 447 GLY B C   1 
ATOM   6353 O O   . GLY B 1 447 ? 163.008 165.455 160.540 1.00 57.96  ? 447 GLY B O   1 
ATOM   6354 N N   . PRO B 1 448 ? 163.756 165.071 158.453 1.00 59.11  ? 448 PRO B N   1 
ATOM   6355 C CA  . PRO B 1 448 ? 162.425 164.627 158.004 1.00 59.11  ? 448 PRO B CA  1 
ATOM   6356 C C   . PRO B 1 448 ? 161.860 163.462 158.795 1.00 59.11  ? 448 PRO B C   1 
ATOM   6357 O O   . PRO B 1 448 ? 160.639 163.391 158.976 1.00 59.11  ? 448 PRO B O   1 
ATOM   6358 C CB  . PRO B 1 448 ? 162.659 164.246 156.538 1.00 59.11  ? 448 PRO B CB  1 
ATOM   6359 C CG  . PRO B 1 448 ? 163.848 165.016 156.121 1.00 59.11  ? 448 PRO B CG  1 
ATOM   6360 C CD  . PRO B 1 448 ? 164.699 165.229 157.332 1.00 59.11  ? 448 PRO B CD  1 
ATOM   6361 N N   . LEU B 1 449 ? 162.704 162.547 159.277 1.00 59.73  ? 449 LEU B N   1 
ATOM   6362 C CA  . LEU B 1 449 ? 162.199 161.393 160.017 1.00 59.73  ? 449 LEU B CA  1 
ATOM   6363 C C   . LEU B 1 449 ? 161.494 161.822 161.299 1.00 59.73  ? 449 LEU B C   1 
ATOM   6364 O O   . LEU B 1 449 ? 160.412 161.320 161.622 1.00 59.73  ? 449 LEU B O   1 
ATOM   6365 C CB  . LEU B 1 449 ? 163.341 160.426 160.328 1.00 59.73  ? 449 LEU B CB  1 
ATOM   6366 C CG  . LEU B 1 449 ? 163.691 159.395 159.254 1.00 59.73  ? 449 LEU B CG  1 
ATOM   6367 C CD1 . LEU B 1 449 ? 164.439 160.032 158.096 1.00 59.73  ? 449 LEU B CD1 1 
ATOM   6368 C CD2 . LEU B 1 449 ? 164.499 158.260 159.855 1.00 59.73  ? 449 LEU B CD2 1 
ATOM   6369 N N   . VAL B 1 450 ? 162.095 162.747 162.047 1.00 59.95  ? 450 VAL B N   1 
ATOM   6370 C CA  . VAL B 1 450 ? 161.460 163.241 163.265 1.00 59.95  ? 450 VAL B CA  1 
ATOM   6371 C C   . VAL B 1 450 ? 160.289 164.156 162.928 1.00 59.95  ? 450 VAL B C   1 
ATOM   6372 O O   . VAL B 1 450 ? 159.262 164.159 163.623 1.00 59.95  ? 450 VAL B O   1 
ATOM   6373 C CB  . VAL B 1 450 ? 162.497 163.949 164.156 1.00 59.95  ? 450 VAL B CB  1 
ATOM   6374 C CG1 . VAL B 1 450 ? 161.890 164.299 165.501 1.00 59.95  ? 450 VAL B CG1 1 
ATOM   6375 C CG2 . VAL B 1 450 ? 163.722 163.073 164.334 1.00 59.95  ? 450 VAL B CG2 1 
ATOM   6376 N N   . LEU B 1 451 ? 160.427 164.957 161.868 1.00 60.72  ? 451 LEU B N   1 
ATOM   6377 C CA  . LEU B 1 451 ? 159.367 165.892 161.509 1.00 60.72  ? 451 LEU B CA  1 
ATOM   6378 C C   . LEU B 1 451 ? 158.089 165.161 161.122 1.00 60.72  ? 451 LEU B C   1 
ATOM   6379 O O   . LEU B 1 451 ? 156.986 165.624 161.431 1.00 60.72  ? 451 LEU B O   1 
ATOM   6380 C CB  . LEU B 1 451 ? 159.829 166.804 160.375 1.00 60.72  ? 451 LEU B CB  1 
ATOM   6381 C CG  . LEU B 1 451 ? 158.788 167.800 159.865 1.00 60.72  ? 451 LEU B CG  1 
ATOM   6382 C CD1 . LEU B 1 451 ? 158.562 168.900 160.882 1.00 60.72  ? 451 LEU B CD1 1 
ATOM   6383 C CD2 . LEU B 1 451 ? 159.208 168.383 158.531 1.00 60.72  ? 451 LEU B CD2 1 
ATOM   6384 N N   . ALA B 1 452 ? 158.214 164.020 160.440 1.00 62.24  ? 452 ALA B N   1 
ATOM   6385 C CA  . ALA B 1 452 ? 157.030 163.255 160.064 1.00 62.24  ? 452 ALA B CA  1 
ATOM   6386 C C   . ALA B 1 452 ? 156.273 162.769 161.293 1.00 62.24  ? 452 ALA B C   1 
ATOM   6387 O O   . ALA B 1 452 ? 155.040 162.861 161.350 1.00 62.24  ? 452 ALA B O   1 
ATOM   6388 C CB  . ALA B 1 452 ? 157.427 162.076 159.177 1.00 62.24  ? 452 ALA B CB  1 
ATOM   6389 N N   . VAL B 1 453 ? 156.995 162.263 162.294 1.00 63.23  ? 453 VAL B N   1 
ATOM   6390 C CA  . VAL B 1 453 ? 156.356 161.805 163.524 1.00 63.23  ? 453 VAL B CA  1 
ATOM   6391 C C   . VAL B 1 453 ? 155.682 162.968 164.241 1.00 63.23  ? 453 VAL B C   1 
ATOM   6392 O O   . VAL B 1 453 ? 154.547 162.848 164.726 1.00 63.23  ? 453 VAL B O   1 
ATOM   6393 C CB  . VAL B 1 453 ? 157.386 161.103 164.427 1.00 63.23  ? 453 VAL B CB  1 
ATOM   6394 C CG1 . VAL B 1 453 ? 156.765 160.737 165.760 1.00 63.23  ? 453 VAL B CG1 1 
ATOM   6395 C CG2 . VAL B 1 453 ? 157.935 159.871 163.737 1.00 63.23  ? 453 VAL B CG2 1 
ATOM   6396 N N   . ILE B 1 454 ? 156.368 164.111 164.321 1.00 62.57  ? 454 ILE B N   1 
ATOM   6397 C CA  . ILE B 1 454 ? 155.797 165.264 165.014 1.00 62.57  ? 454 ILE B CA  1 
ATOM   6398 C C   . ILE B 1 454 ? 154.526 165.736 164.316 1.00 62.57  ? 454 ILE B C   1 
ATOM   6399 O O   . ILE B 1 454 ? 153.516 166.037 164.965 1.00 62.57  ? 454 ILE B O   1 
ATOM   6400 C CB  . ILE B 1 454 ? 156.837 166.392 165.127 1.00 62.57  ? 454 ILE B CB  1 
ATOM   6401 C CG1 . ILE B 1 454 ? 158.009 165.946 165.999 1.00 62.57  ? 454 ILE B CG1 1 
ATOM   6402 C CG2 . ILE B 1 454 ? 156.206 167.641 165.704 1.00 62.57  ? 454 ILE B CG2 1 
ATOM   6403 C CD1 . ILE B 1 454 ? 157.596 165.425 167.350 1.00 62.57  ? 454 ILE B CD1 1 
ATOM   6404 N N   . GLN B 1 455 ? 154.551 165.799 162.983 1.00 64.96  ? 455 GLN B N   1 
ATOM   6405 C CA  . GLN B 1 455 ? 153.375 166.240 162.242 1.00 64.96  ? 455 GLN B CA  1 
ATOM   6406 C C   . GLN B 1 455 ? 152.230 165.244 162.368 1.00 64.96  ? 455 GLN B C   1 
ATOM   6407 O O   . GLN B 1 455 ? 151.063 165.644 162.440 1.00 64.96  ? 455 GLN B O   1 
ATOM   6408 C CB  . GLN B 1 455 ? 153.733 166.467 160.776 1.00 64.96  ? 455 GLN B CB  1 
ATOM   6409 C CG  . GLN B 1 455 ? 153.966 167.924 160.425 1.00 64.96  ? 455 GLN B CG  1 
ATOM   6410 C CD  . GLN B 1 455 ? 154.602 168.100 159.063 1.00 64.96  ? 455 GLN B CD  1 
ATOM   6411 O OE1 . GLN B 1 455 ? 154.831 167.130 158.342 1.00 64.96  ? 455 GLN B OE1 1 
ATOM   6412 N NE2 . GLN B 1 455 ? 154.888 169.344 158.701 1.00 64.96  ? 455 GLN B NE2 1 
ATOM   6413 N N   . ALA B 1 456 ? 152.537 163.945 162.389 1.00 66.22  ? 456 ALA B N   1 
ATOM   6414 C CA  . ALA B 1 456 ? 151.488 162.951 162.594 1.00 66.22  ? 456 ALA B CA  1 
ATOM   6415 C C   . ALA B 1 456 ? 150.835 163.118 163.959 1.00 66.22  ? 456 ALA B C   1 
ATOM   6416 O O   . ALA B 1 456 ? 149.605 163.052 164.082 1.00 66.22  ? 456 ALA B O   1 
ATOM   6417 C CB  . ALA B 1 456 ? 152.061 161.543 162.441 1.00 66.22  ? 456 ALA B CB  1 
ATOM   6418 N N   . VAL B 1 457 ? 151.645 163.349 164.995 1.00 65.66  ? 457 VAL B N   1 
ATOM   6419 C CA  . VAL B 1 457 ? 151.098 163.571 166.332 1.00 65.66  ? 457 VAL B CA  1 
ATOM   6420 C C   . VAL B 1 457 ? 150.222 164.818 166.350 1.00 65.66  ? 457 VAL B C   1 
ATOM   6421 O O   . VAL B 1 457 ? 149.132 164.823 166.940 1.00 65.66  ? 457 VAL B O   1 
ATOM   6422 C CB  . VAL B 1 457 ? 152.236 163.665 167.364 1.00 65.66  ? 457 VAL B CB  1 
ATOM   6423 C CG1 . VAL B 1 457 ? 151.709 164.177 168.691 1.00 65.66  ? 457 VAL B CG1 1 
ATOM   6424 C CG2 . VAL B 1 457 ? 152.907 162.315 167.535 1.00 65.66  ? 457 VAL B CG2 1 
ATOM   6425 N N   . ILE B 1 458 ? 150.683 165.894 165.708 1.00 66.28  ? 458 ILE B N   1 
ATOM   6426 C CA  . ILE B 1 458 ? 149.921 167.140 165.692 1.00 66.28  ? 458 ILE B CA  1 
ATOM   6427 C C   . ILE B 1 458 ? 148.589 166.950 164.975 1.00 66.28  ? 458 ILE B C   1 
ATOM   6428 O O   . ILE B 1 458 ? 147.549 167.436 165.431 1.00 66.28  ? 458 ILE B O   1 
ATOM   6429 C CB  . ILE B 1 458 ? 150.755 168.268 165.057 1.00 66.28  ? 458 ILE B CB  1 
ATOM   6430 C CG1 . ILE B 1 458 ? 151.866 168.704 166.011 1.00 66.28  ? 458 ILE B CG1 1 
ATOM   6431 C CG2 . ILE B 1 458 ? 149.878 169.452 164.700 1.00 66.28  ? 458 ILE B CG2 1 
ATOM   6432 C CD1 . ILE B 1 458 ? 152.867 169.645 165.392 1.00 66.28  ? 458 ILE B CD1 1 
ATOM   6433 N N   . THR B 1 459 ? 148.598 166.246 163.841 1.00 69.71  ? 459 THR B N   1 
ATOM   6434 C CA  . THR B 1 459 ? 147.357 166.004 163.109 1.00 69.71  ? 459 THR B CA  1 
ATOM   6435 C C   . THR B 1 459 ? 146.392 165.146 163.919 1.00 69.71  ? 459 THR B C   1 
ATOM   6436 O O   . THR B 1 459 ? 145.182 165.410 163.943 1.00 69.71  ? 459 THR B O   1 
ATOM   6437 C CB  . THR B 1 459 ? 147.659 165.338 161.768 1.00 69.71  ? 459 THR B CB  1 
ATOM   6438 O OG1 . THR B 1 459 ? 148.648 166.101 161.066 1.00 69.71  ? 459 THR B OG1 1 
ATOM   6439 C CG2 . THR B 1 459 ? 146.400 165.252 160.924 1.00 69.71  ? 459 THR B CG2 1 
ATOM   6440 N N   . SER B 1 460 ? 146.908 164.111 164.587 1.00 70.89  ? 460 SER B N   1 
ATOM   6441 C CA  . SER B 1 460 ? 146.049 163.272 165.414 1.00 70.89  ? 460 SER B CA  1 
ATOM   6442 C C   . SER B 1 460 ? 145.427 164.074 166.549 1.00 70.89  ? 460 SER B C   1 
ATOM   6443 O O   . SER B 1 460 ? 144.235 163.926 166.843 1.00 70.89  ? 460 SER B O   1 
ATOM   6444 C CB  . SER B 1 460 ? 146.847 162.090 165.963 1.00 70.89  ? 460 SER B CB  1 
ATOM   6445 O OG  . SER B 1 460 ? 146.062 161.311 166.846 1.00 70.89  ? 460 SER B OG  1 
ATOM   6446 N N   . ARG B 1 461 ? 146.217 164.934 167.196 1.00 72.61  ? 461 ARG B N   1 
ATOM   6447 C CA  . ARG B 1 461 ? 145.680 165.757 168.274 1.00 72.61  ? 461 ARG B CA  1 
ATOM   6448 C C   . ARG B 1 461 ? 144.674 166.779 167.759 1.00 72.61  ? 461 ARG B C   1 
ATOM   6449 O O   . ARG B 1 461 ? 143.699 167.087 168.452 1.00 72.61  ? 461 ARG B O   1 
ATOM   6450 C CB  . ARG B 1 461 ? 146.817 166.454 169.018 1.00 72.61  ? 461 ARG B CB  1 
ATOM   6451 C CG  . ARG B 1 461 ? 146.396 167.119 170.314 1.00 72.61  ? 461 ARG B CG  1 
ATOM   6452 C CD  . ARG B 1 461 ? 145.487 166.220 171.128 1.00 72.61  ? 461 ARG B CD  1 
ATOM   6453 N NE  . ARG B 1 461 ? 145.259 166.746 172.468 1.00 72.61  ? 461 ARG B NE  1 
ATOM   6454 C CZ  . ARG B 1 461 ? 145.651 166.148 173.583 1.00 72.61  ? 461 ARG B CZ  1 
ATOM   6455 N NH1 . ARG B 1 461 ? 146.283 164.986 173.559 1.00 72.61  ? 461 ARG B NH1 1 
ATOM   6456 N NH2 . ARG B 1 461 ? 145.399 166.727 174.753 1.00 72.61  ? 461 ARG B NH2 1 
ATOM   6457 N N   . THR B 1 462 ? 144.898 167.323 166.560 1.00 73.66  ? 462 THR B N   1 
ATOM   6458 C CA  . THR B 1 462 ? 143.928 168.240 165.970 1.00 73.66  ? 462 THR B CA  1 
ATOM   6459 C C   . THR B 1 462 ? 142.604 167.542 165.708 1.00 73.66  ? 462 THR B C   1 
ATOM   6460 O O   . THR B 1 462 ? 141.534 168.098 165.981 1.00 73.66  ? 462 THR B O   1 
ATOM   6461 C CB  . THR B 1 462 ? 144.475 168.825 164.670 1.00 73.66  ? 462 THR B CB  1 
ATOM   6462 O OG1 . THR B 1 462 ? 145.796 169.332 164.888 1.00 73.66  ? 462 THR B OG1 1 
ATOM   6463 C CG2 . THR B 1 462 ? 143.580 169.945 164.173 1.00 73.66  ? 462 THR B CG2 1 
ATOM   6464 N N   . LEU B 1 463 ? 142.655 166.322 165.171 1.00 76.76  ? 463 LEU B N   1 
ATOM   6465 C CA  . LEU B 1 463 ? 141.423 165.587 164.908 1.00 76.76  ? 463 LEU B CA  1 
ATOM   6466 C C   . LEU B 1 463 ? 140.735 165.160 166.198 1.00 76.76  ? 463 LEU B C   1 
ATOM   6467 O O   . LEU B 1 463 ? 139.502 165.102 166.248 1.00 76.76  ? 463 LEU B O   1 
ATOM   6468 C CB  . LEU B 1 463 ? 141.710 164.374 164.026 1.00 76.76  ? 463 LEU B CB  1 
ATOM   6469 C CG  . LEU B 1 463 ? 142.104 164.705 162.586 1.00 76.76  ? 463 LEU B CG  1 
ATOM   6470 C CD1 . LEU B 1 463 ? 142.345 163.437 161.788 1.00 76.76  ? 463 LEU B CD1 1 
ATOM   6471 C CD2 . LEU B 1 463 ? 141.039 165.562 161.929 1.00 76.76  ? 463 LEU B CD2 1 
ATOM   6472 N N   . TYR B 1 464 ? 141.507 164.853 167.243 1.00 77.87  ? 464 TYR B N   1 
ATOM   6473 C CA  . TYR B 1 464 ? 140.910 164.464 168.517 1.00 77.87  ? 464 TYR B CA  1 
ATOM   6474 C C   . TYR B 1 464 ? 140.128 165.613 169.143 1.00 77.87  ? 464 TYR B C   1 
ATOM   6475 O O   . TYR B 1 464 ? 139.021 165.410 169.653 1.00 77.87  ? 464 TYR B O   1 
ATOM   6476 C CB  . TYR B 1 464 ? 141.993 163.974 169.476 1.00 77.87  ? 464 TYR B CB  1 
ATOM   6477 C CG  . TYR B 1 464 ? 141.520 163.792 170.900 1.00 77.87  ? 464 TYR B CG  1 
ATOM   6478 C CD1 . TYR B 1 464 ? 140.385 163.048 171.187 1.00 77.87  ? 464 TYR B CD1 1 
ATOM   6479 C CD2 . TYR B 1 464 ? 142.210 164.366 171.957 1.00 77.87  ? 464 TYR B CD2 1 
ATOM   6480 C CE1 . TYR B 1 464 ? 139.950 162.883 172.487 1.00 77.87  ? 464 TYR B CE1 1 
ATOM   6481 C CE2 . TYR B 1 464 ? 141.784 164.205 173.259 1.00 77.87  ? 464 TYR B CE2 1 
ATOM   6482 C CZ  . TYR B 1 464 ? 140.654 163.463 173.519 1.00 77.87  ? 464 TYR B CZ  1 
ATOM   6483 O OH  . TYR B 1 464 ? 140.226 163.300 174.816 1.00 77.87  ? 464 TYR B OH  1 
ATOM   6484 N N   . LEU B 1 465 ? 140.681 166.825 169.111 1.00 77.84  ? 465 LEU B N   1 
ATOM   6485 C CA  . LEU B 1 465 ? 140.045 167.961 169.765 1.00 77.84  ? 465 LEU B CA  1 
ATOM   6486 C C   . LEU B 1 465 ? 138.895 168.548 168.959 1.00 77.84  ? 465 LEU B C   1 
ATOM   6487 O O   . LEU B 1 465 ? 138.213 169.451 169.455 1.00 77.84  ? 465 LEU B O   1 
ATOM   6488 C CB  . LEU B 1 465 ? 141.080 169.052 170.048 1.00 77.84  ? 465 LEU B CB  1 
ATOM   6489 C CG  . LEU B 1 465 ? 142.082 168.767 171.168 1.00 77.84  ? 465 LEU B CG  1 
ATOM   6490 C CD1 . LEU B 1 465 ? 142.780 170.045 171.599 1.00 77.84  ? 465 LEU B CD1 1 
ATOM   6491 C CD2 . LEU B 1 465 ? 141.397 168.105 172.350 1.00 77.84  ? 465 LEU B CD2 1 
ATOM   6492 N N   . GLY B 1 466 ? 138.664 168.068 167.741 1.00 82.64  ? 466 GLY B N   1 
ATOM   6493 C CA  . GLY B 1 466 ? 137.572 168.567 166.930 1.00 82.64  ? 466 GLY B CA  1 
ATOM   6494 C C   . GLY B 1 466 ? 137.996 169.623 165.932 1.00 82.64  ? 466 GLY B C   1 
ATOM   6495 O O   . GLY B 1 466 ? 137.358 170.674 165.822 1.00 82.64  ? 466 GLY B O   1 
ATOM   6496 N N   . GLY B 1 467 ? 139.070 169.355 165.197 1.00 86.61  ? 467 GLY B N   1 
ATOM   6497 C CA  . GLY B 1 467 ? 139.579 170.263 164.197 1.00 86.61  ? 467 GLY B CA  1 
ATOM   6498 C C   . GLY B 1 467 ? 139.175 169.866 162.792 1.00 86.61  ? 467 GLY B C   1 
ATOM   6499 O O   . GLY B 1 467 ? 138.227 169.103 162.576 1.00 86.61  ? 467 GLY B O   1 
ATOM   6500 N N   . THR B 1 468 ? 139.910 170.397 161.819 1.00 93.82  ? 468 THR B N   1 
ATOM   6501 C CA  . THR B 1 468 ? 139.659 170.120 160.413 1.00 93.82  ? 468 THR B CA  1 
ATOM   6502 C C   . THR B 1 468 ? 140.991 169.960 159.696 1.00 93.82  ? 468 THR B C   1 
ATOM   6503 O O   . THR B 1 468 ? 142.014 170.497 160.129 1.00 93.82  ? 468 THR B O   1 
ATOM   6504 C CB  . THR B 1 468 ? 138.830 171.238 159.762 1.00 93.82  ? 468 THR B CB  1 
ATOM   6505 O OG1 . THR B 1 468 ? 137.758 171.606 160.639 1.00 93.82  ? 468 THR B OG1 1 
ATOM   6506 C CG2 . THR B 1 468 ? 138.238 170.775 158.439 1.00 93.82  ? 468 THR B CG2 1 
ATOM   6507 N N   . THR B 1 469 ? 140.971 169.211 158.595 1.00 96.08  ? 469 THR B N   1 
ATOM   6508 C CA  . THR B 1 469 ? 142.158 168.969 157.786 1.00 96.08  ? 469 THR B CA  1 
ATOM   6509 C C   . THR B 1 469 ? 142.262 169.914 156.596 1.00 96.08  ? 469 THR B C   1 
ATOM   6510 O O   . THR B 1 469 ? 143.127 169.718 155.737 1.00 96.08  ? 469 THR B O   1 
ATOM   6511 C CB  . THR B 1 469 ? 142.178 167.519 157.300 1.00 96.08  ? 469 THR B CB  1 
ATOM   6512 O OG1 . THR B 1 469 ? 141.028 167.272 156.481 1.00 96.08  ? 469 THR B OG1 1 
ATOM   6513 C CG2 . THR B 1 469 ? 142.165 166.564 158.479 1.00 96.08  ? 469 THR B CG2 1 
ATOM   6514 N N   . GLY B 1 470 ? 141.405 170.929 156.523 1.00 98.88  ? 470 GLY B N   1 
ATOM   6515 C CA  . GLY B 1 470 ? 141.419 171.858 155.420 1.00 98.88  ? 470 GLY B CA  1 
ATOM   6516 C C   . GLY B 1 470 ? 142.427 172.972 155.608 1.00 98.88  ? 470 GLY B C   1 
ATOM   6517 O O   . GLY B 1 470 ? 143.232 172.962 156.544 1.00 98.88  ? 470 GLY B O   1 
ATOM   6518 N N   . PRO B 1 471 ? 142.410 173.952 154.706 1.00 101.62 ? 471 PRO B N   1 
ATOM   6519 C CA  . PRO B 1 471 ? 143.321 175.093 154.841 1.00 101.62 ? 471 PRO B CA  1 
ATOM   6520 C C   . PRO B 1 471 ? 143.001 175.921 156.075 1.00 101.62 ? 471 PRO B C   1 
ATOM   6521 O O   . PRO B 1 471 ? 141.869 175.944 156.564 1.00 101.62 ? 471 PRO B O   1 
ATOM   6522 C CB  . PRO B 1 471 ? 143.082 175.896 153.556 1.00 101.62 ? 471 PRO B CB  1 
ATOM   6523 C CG  . PRO B 1 471 ? 142.442 174.930 152.610 1.00 101.62 ? 471 PRO B CG  1 
ATOM   6524 C CD  . PRO B 1 471 ? 141.626 174.016 153.464 1.00 101.62 ? 471 PRO B CD  1 
ATOM   6525 N N   . VAL B 1 472 ? 144.029 176.605 156.581 1.00 98.56  ? 472 VAL B N   1 
ATOM   6526 C CA  . VAL B 1 472 ? 143.884 177.372 157.816 1.00 98.56  ? 472 VAL B CA  1 
ATOM   6527 C C   . VAL B 1 472 ? 142.871 178.496 157.638 1.00 98.56  ? 472 VAL B C   1 
ATOM   6528 O O   . VAL B 1 472 ? 142.044 178.752 158.521 1.00 98.56  ? 472 VAL B O   1 
ATOM   6529 C CB  . VAL B 1 472 ? 145.252 177.908 158.274 1.00 98.56  ? 472 VAL B CB  1 
ATOM   6530 C CG1 . VAL B 1 472 ? 145.132 178.576 159.632 1.00 98.56  ? 472 VAL B CG1 1 
ATOM   6531 C CG2 . VAL B 1 472 ? 146.270 176.783 158.317 1.00 98.56  ? 472 VAL B CG2 1 
ATOM   6532 N N   . LYS B 1 473 ? 142.916 179.181 156.499 1.00 103.55 ? 473 LYS B N   1 
ATOM   6533 C CA  . LYS B 1 473 ? 142.042 180.320 156.244 1.00 103.55 ? 473 LYS B CA  1 
ATOM   6534 C C   . LYS B 1 473 ? 140.611 179.919 155.891 1.00 103.55 ? 473 LYS B C   1 
ATOM   6535 O O   . LYS B 1 473 ? 139.820 180.784 155.503 1.00 103.55 ? 473 LYS B O   1 
ATOM   6536 C CB  . LYS B 1 473 ? 142.659 181.202 155.152 1.00 103.55 ? 473 LYS B CB  1 
ATOM   6537 C CG  . LYS B 1 473 ? 142.876 180.536 153.799 1.00 103.55 ? 473 LYS B CG  1 
ATOM   6538 C CD  . LYS B 1 473 ? 141.742 180.784 152.823 1.00 103.55 ? 473 LYS B CD  1 
ATOM   6539 C CE  . LYS B 1 473 ? 142.104 180.241 151.449 1.00 103.55 ? 473 LYS B CE  1 
ATOM   6540 N NZ  . LYS B 1 473 ? 141.041 180.485 150.439 1.00 103.55 ? 473 LYS B NZ  1 
ATOM   6541 N N   . PHE B 1 474 ? 140.264 178.641 156.031 1.00 104.05 ? 474 PHE B N   1 
ATOM   6542 C CA  . PHE B 1 474 ? 138.896 178.146 155.923 1.00 104.05 ? 474 PHE B CA  1 
ATOM   6543 C C   . PHE B 1 474 ? 138.432 177.532 157.238 1.00 104.05 ? 474 PHE B C   1 
ATOM   6544 O O   . PHE B 1 474 ? 137.746 176.509 157.258 1.00 104.05 ? 474 PHE B O   1 
ATOM   6545 C CB  . PHE B 1 474 ? 138.764 177.128 154.793 1.00 104.05 ? 474 PHE B CB  1 
ATOM   6546 C CG  . PHE B 1 474 ? 138.656 177.739 153.427 1.00 104.05 ? 474 PHE B CG  1 
ATOM   6547 C CD1 . PHE B 1 474 ? 138.714 176.942 152.296 1.00 104.05 ? 474 PHE B CD1 1 
ATOM   6548 C CD2 . PHE B 1 474 ? 138.462 179.099 153.272 1.00 104.05 ? 474 PHE B CD2 1 
ATOM   6549 C CE1 . PHE B 1 474 ? 138.603 177.493 151.037 1.00 104.05 ? 474 PHE B CE1 1 
ATOM   6550 C CE2 . PHE B 1 474 ? 138.349 179.657 152.014 1.00 104.05 ? 474 PHE B CE2 1 
ATOM   6551 C CZ  . PHE B 1 474 ? 138.419 178.851 150.895 1.00 104.05 ? 474 PHE B CZ  1 
ATOM   6552 N N   . MET B 1 475 ? 138.798 178.150 158.355 1.00 97.74  ? 475 MET B N   1 
ATOM   6553 C CA  . MET B 1 475 ? 138.503 177.623 159.680 1.00 97.74  ? 475 MET B CA  1 
ATOM   6554 C C   . MET B 1 475 ? 137.747 178.662 160.503 1.00 97.74  ? 475 MET B C   1 
ATOM   6555 O O   . MET B 1 475 ? 137.513 179.791 160.067 1.00 97.74  ? 475 MET B O   1 
ATOM   6556 C CB  . MET B 1 475 ? 139.789 177.198 160.394 1.00 97.74  ? 475 MET B CB  1 
ATOM   6557 C CG  . MET B 1 475 ? 140.342 175.859 159.939 1.00 97.74  ? 475 MET B CG  1 
ATOM   6558 S SD  . MET B 1 475 ? 141.669 175.272 161.006 1.00 97.74  ? 475 MET B SD  1 
ATOM   6559 C CE  . MET B 1 475 ? 142.674 174.375 159.831 1.00 97.74  ? 475 MET B CE  1 
ATOM   6560 N N   . ASN B 1 476 ? 137.364 178.259 161.709 1.00 96.94  ? 476 ASN B N   1 
ATOM   6561 C CA  . ASN B 1 476 ? 136.657 179.098 162.666 1.00 96.94  ? 476 ASN B CA  1 
ATOM   6562 C C   . ASN B 1 476 ? 137.485 179.213 163.942 1.00 96.94  ? 476 ASN B C   1 
ATOM   6563 O O   . ASN B 1 476 ? 138.624 178.746 164.014 1.00 96.94  ? 476 ASN B O   1 
ATOM   6564 C CB  . ASN B 1 476 ? 135.264 178.534 162.960 1.00 96.94  ? 476 ASN B CB  1 
ATOM   6565 C CG  . ASN B 1 476 ? 134.273 179.607 163.365 1.00 96.94  ? 476 ASN B CG  1 
ATOM   6566 O OD1 . ASN B 1 476 ? 134.489 180.332 164.336 1.00 96.94  ? 476 ASN B OD1 1 
ATOM   6567 N ND2 . ASN B 1 476 ? 133.178 179.714 162.622 1.00 96.94  ? 476 ASN B ND2 1 
ATOM   6568 N N   . ASP B 1 477 ? 136.900 179.849 164.958 1.00 96.91  ? 477 ASP B N   1 
ATOM   6569 C CA  . ASP B 1 477 ? 137.621 180.064 166.209 1.00 96.91  ? 477 ASP B CA  1 
ATOM   6570 C C   . ASP B 1 477 ? 137.926 178.749 166.917 1.00 96.91  ? 477 ASP B C   1 
ATOM   6571 O O   . ASP B 1 477 ? 139.039 178.553 167.418 1.00 96.91  ? 477 ASP B O   1 
ATOM   6572 C CB  . ASP B 1 477 ? 136.819 180.988 167.122 1.00 96.91  ? 477 ASP B CB  1 
ATOM   6573 C CG  . ASP B 1 477 ? 136.867 182.433 166.674 1.00 96.91  ? 477 ASP B CG  1 
ATOM   6574 O OD1 . ASP B 1 477 ? 137.887 182.838 166.077 1.00 96.91  ? 477 ASP B OD1 1 
ATOM   6575 O OD2 . ASP B 1 477 ? 135.885 183.164 166.918 1.00 96.91  ? 477 ASP B OD2 1 
ATOM   6576 N N   . VAL B 1 478 ? 136.954 177.835 166.969 1.00 93.79  ? 478 VAL B N   1 
ATOM   6577 C CA  . VAL B 1 478 ? 137.142 176.598 167.722 1.00 93.79  ? 478 VAL B CA  1 
ATOM   6578 C C   . VAL B 1 478 ? 138.156 175.688 167.033 1.00 93.79  ? 478 VAL B C   1 
ATOM   6579 O O   . VAL B 1 478 ? 139.001 175.066 167.691 1.00 93.79  ? 478 VAL B O   1 
ATOM   6580 C CB  . VAL B 1 478 ? 135.787 175.900 167.943 1.00 93.79  ? 478 VAL B CB  1 
ATOM   6581 C CG1 . VAL B 1 478 ? 134.880 176.785 168.777 1.00 93.79  ? 478 VAL B CG1 1 
ATOM   6582 C CG2 . VAL B 1 478 ? 135.116 175.581 166.618 1.00 93.79  ? 478 VAL B CG2 1 
ATOM   6583 N N   . GLN B 1 479 ? 138.103 175.603 165.702 1.00 91.91  ? 479 GLN B N   1 
ATOM   6584 C CA  . GLN B 1 479 ? 139.080 174.799 164.976 1.00 91.91  ? 479 GLN B CA  1 
ATOM   6585 C C   . GLN B 1 479 ? 140.482 175.382 165.107 1.00 91.91  ? 479 GLN B C   1 
ATOM   6586 O O   . GLN B 1 479 ? 141.462 174.639 165.246 1.00 91.91  ? 479 GLN B O   1 
ATOM   6587 C CB  . GLN B 1 479 ? 138.667 174.682 163.509 1.00 91.91  ? 479 GLN B CB  1 
ATOM   6588 C CG  . GLN B 1 479 ? 137.246 174.172 163.321 1.00 91.91  ? 479 GLN B CG  1 
ATOM   6589 C CD  . GLN B 1 479 ? 136.703 174.431 161.930 1.00 91.91  ? 479 GLN B CD  1 
ATOM   6590 O OE1 . GLN B 1 479 ? 136.861 173.611 161.027 1.00 91.91  ? 479 GLN B OE1 1 
ATOM   6591 N NE2 . GLN B 1 479 ? 136.050 175.571 161.754 1.00 91.91  ? 479 GLN B NE2 1 
ATOM   6592 N N   . LEU B 1 480 ? 140.598 176.712 165.074 1.00 87.39  ? 480 LEU B N   1 
ATOM   6593 C CA  . LEU B 1 480 ? 141.900 177.342 165.268 1.00 87.39  ? 480 LEU B CA  1 
ATOM   6594 C C   . LEU B 1 480 ? 142.431 177.093 166.675 1.00 87.39  ? 480 LEU B C   1 
ATOM   6595 O O   . LEU B 1 480 ? 143.634 176.872 166.861 1.00 87.39  ? 480 LEU B O   1 
ATOM   6596 C CB  . LEU B 1 480 ? 141.806 178.838 164.979 1.00 87.39  ? 480 LEU B CB  1 
ATOM   6597 C CG  . LEU B 1 480 ? 141.809 179.219 163.497 1.00 87.39  ? 480 LEU B CG  1 
ATOM   6598 C CD1 . LEU B 1 480 ? 141.502 180.696 163.319 1.00 87.39  ? 480 LEU B CD1 1 
ATOM   6599 C CD2 . LEU B 1 480 ? 143.139 178.865 162.856 1.00 87.39  ? 480 LEU B CD2 1 
ATOM   6600 N N   . ALA B 1 481 ? 141.553 177.130 167.680 1.00 82.57  ? 481 ALA B N   1 
ATOM   6601 C CA  . ALA B 1 481 ? 141.977 176.811 169.039 1.00 82.57  ? 481 ALA B CA  1 
ATOM   6602 C C   . ALA B 1 481 ? 142.459 175.370 169.137 1.00 82.57  ? 481 ALA B C   1 
ATOM   6603 O O   . ALA B 1 481 ? 143.456 175.081 169.813 1.00 82.57  ? 481 ALA B O   1 
ATOM   6604 C CB  . ALA B 1 481 ? 140.833 177.065 170.019 1.00 82.57  ? 481 ALA B CB  1 
ATOM   6605 N N   . ALA B 1 482 ? 141.758 174.451 168.470 1.00 78.44  ? 482 ALA B N   1 
ATOM   6606 C CA  . ALA B 1 482 ? 142.197 173.060 168.450 1.00 78.44  ? 482 ALA B CA  1 
ATOM   6607 C C   . ALA B 1 482 ? 143.574 172.927 167.811 1.00 78.44  ? 482 ALA B C   1 
ATOM   6608 O O   . ALA B 1 482 ? 144.431 172.188 168.311 1.00 78.44  ? 482 ALA B O   1 
ATOM   6609 C CB  . ALA B 1 482 ? 141.174 172.200 167.712 1.00 78.44  ? 482 ALA B CB  1 
ATOM   6610 N N   . LEU B 1 483 ? 143.806 173.639 166.705 1.00 74.95  ? 483 LEU B N   1 
ATOM   6611 C CA  . LEU B 1 483 ? 145.113 173.589 166.054 1.00 74.95  ? 483 LEU B CA  1 
ATOM   6612 C C   . LEU B 1 483 ? 146.209 174.142 166.961 1.00 74.95  ? 483 LEU B C   1 
ATOM   6613 O O   . LEU B 1 483 ? 147.307 173.573 167.044 1.00 74.95  ? 483 LEU B O   1 
ATOM   6614 C CB  . LEU B 1 483 ? 145.068 174.358 164.734 1.00 74.95  ? 483 LEU B CB  1 
ATOM   6615 C CG  . LEU B 1 483 ? 146.232 174.118 163.773 1.00 74.95  ? 483 LEU B CG  1 
ATOM   6616 C CD1 . LEU B 1 483 ? 146.367 172.643 163.449 1.00 74.95  ? 483 LEU B CD1 1 
ATOM   6617 C CD2 . LEU B 1 483 ? 146.053 174.931 162.506 1.00 74.95  ? 483 LEU B CD2 1 
ATOM   6618 N N   . ASP B 1 484 ? 145.930 175.254 167.644 1.00 73.02  ? 484 ASP B N   1 
ATOM   6619 C CA  . ASP B 1 484 ? 146.911 175.832 168.559 1.00 73.02  ? 484 ASP B CA  1 
ATOM   6620 C C   . ASP B 1 484 ? 147.257 174.862 169.682 1.00 73.02  ? 484 ASP B C   1 
ATOM   6621 O O   . ASP B 1 484 ? 148.435 174.686 170.030 1.00 73.02  ? 484 ASP B O   1 
ATOM   6622 C CB  . ASP B 1 484 ? 146.374 177.145 169.129 1.00 73.02  ? 484 ASP B CB  1 
ATOM   6623 C CG  . ASP B 1 484 ? 147.351 177.818 170.068 1.00 73.02  ? 484 ASP B CG  1 
ATOM   6624 O OD1 . ASP B 1 484 ? 147.463 177.385 171.233 1.00 73.02  ? 484 ASP B OD1 1 
ATOM   6625 O OD2 . ASP B 1 484 ? 148.008 178.790 169.642 1.00 73.02  ? 484 ASP B OD2 1 
ATOM   6626 N N   . HIS B 1 485 ? 146.240 174.224 170.265 1.00 73.04  ? 485 HIS B N   1 
ATOM   6627 C CA  . HIS B 1 485 ? 146.496 173.264 171.331 1.00 73.04  ? 485 HIS B CA  1 
ATOM   6628 C C   . HIS B 1 485 ? 147.272 172.060 170.814 1.00 73.04  ? 485 HIS B C   1 
ATOM   6629 O O   . HIS B 1 485 ? 148.133 171.522 171.519 1.00 73.04  ? 485 HIS B O   1 
ATOM   6630 C CB  . HIS B 1 485 ? 145.181 172.837 171.976 1.00 73.04  ? 485 HIS B CB  1 
ATOM   6631 C CG  . HIS B 1 485 ? 144.474 173.949 172.685 1.00 73.04  ? 485 HIS B CG  1 
ATOM   6632 N ND1 . HIS B 1 485 ? 145.146 174.933 173.377 1.00 73.04  ? 485 HIS B ND1 1 
ATOM   6633 C CD2 . HIS B 1 485 ? 143.157 174.238 172.806 1.00 73.04  ? 485 HIS B CD2 1 
ATOM   6634 C CE1 . HIS B 1 485 ? 144.274 175.779 173.895 1.00 73.04  ? 485 HIS B CE1 1 
ATOM   6635 N NE2 . HIS B 1 485 ? 143.060 175.379 173.563 1.00 73.04  ? 485 HIS B NE2 1 
ATOM   6636 N N   . ALA B 1 486 ? 146.997 171.632 169.580 1.00 69.21  ? 486 ALA B N   1 
ATOM   6637 C CA  . ALA B 1 486 ? 147.759 170.533 168.995 1.00 69.21  ? 486 ALA B CA  1 
ATOM   6638 C C   . ALA B 1 486 ? 149.230 170.897 168.838 1.00 69.21  ? 486 ALA B C   1 
ATOM   6639 O O   . ALA B 1 486 ? 150.115 170.073 169.101 1.00 69.21  ? 486 ALA B O   1 
ATOM   6640 C CB  . ALA B 1 486 ? 147.159 170.143 167.647 1.00 69.21  ? 486 ALA B CB  1 
ATOM   6641 N N   . TYR B 1 487 ? 149.511 172.126 168.398 1.00 67.25  ? 487 TYR B N   1 
ATOM   6642 C CA  . TYR B 1 487 ? 150.900 172.557 168.255 1.00 67.25  ? 487 TYR B CA  1 
ATOM   6643 C C   . TYR B 1 487 ? 151.610 172.586 169.604 1.00 67.25  ? 487 TYR B C   1 
ATOM   6644 O O   . TYR B 1 487 ? 152.735 172.077 169.750 1.00 67.25  ? 487 TYR B O   1 
ATOM   6645 C CB  . TYR B 1 487 ? 150.953 173.930 167.589 1.00 67.25  ? 487 TYR B CB  1 
ATOM   6646 C CG  . TYR B 1 487 ? 151.005 173.877 166.082 1.00 67.25  ? 487 TYR B CG  1 
ATOM   6647 C CD1 . TYR B 1 487 ? 152.170 173.520 165.421 1.00 67.25  ? 487 TYR B CD1 1 
ATOM   6648 C CD2 . TYR B 1 487 ? 149.890 174.186 165.319 1.00 67.25  ? 487 TYR B CD2 1 
ATOM   6649 C CE1 . TYR B 1 487 ? 152.222 173.470 164.046 1.00 67.25  ? 487 TYR B CE1 1 
ATOM   6650 C CE2 . TYR B 1 487 ? 149.933 174.139 163.943 1.00 67.25  ? 487 TYR B CE2 1 
ATOM   6651 C CZ  . TYR B 1 487 ? 151.100 173.780 163.312 1.00 67.25  ? 487 TYR B CZ  1 
ATOM   6652 O OH  . TYR B 1 487 ? 151.147 173.731 161.939 1.00 67.25  ? 487 TYR B OH  1 
ATOM   6653 N N   . THR B 1 488 ? 150.962 173.181 170.610 1.00 66.97  ? 488 THR B N   1 
ATOM   6654 C CA  . THR B 1 488 ? 151.561 173.218 171.939 1.00 66.97  ? 488 THR B CA  1 
ATOM   6655 C C   . THR B 1 488 ? 151.705 171.828 172.545 1.00 66.97  ? 488 THR B C   1 
ATOM   6656 O O   . THR B 1 488 ? 152.555 171.632 173.418 1.00 66.97  ? 488 THR B O   1 
ATOM   6657 C CB  . THR B 1 488 ? 150.741 174.109 172.870 1.00 66.97  ? 488 THR B CB  1 
ATOM   6658 O OG1 . THR B 1 488 ? 149.418 173.577 173.001 1.00 66.97  ? 488 THR B OG1 1 
ATOM   6659 C CG2 . THR B 1 488 ? 150.663 175.521 172.319 1.00 66.97  ? 488 THR B CG2 1 
ATOM   6660 N N   . TYR B 1 489 ? 150.892 170.866 172.107 1.00 66.66  ? 489 TYR B N   1 
ATOM   6661 C CA  . TYR B 1 489 ? 151.053 169.484 172.543 1.00 66.66  ? 489 TYR B CA  1 
ATOM   6662 C C   . TYR B 1 489 ? 152.249 168.818 171.871 1.00 66.66  ? 489 TYR B C   1 
ATOM   6663 O O   . TYR B 1 489 ? 152.993 168.077 172.521 1.00 66.66  ? 489 TYR B O   1 
ATOM   6664 C CB  . TYR B 1 489 ? 149.769 168.703 172.260 1.00 66.66  ? 489 TYR B CB  1 
ATOM   6665 C CG  . TYR B 1 489 ? 149.849 167.225 172.560 1.00 66.66  ? 489 TYR B CG  1 
ATOM   6666 C CD1 . TYR B 1 489 ? 149.816 166.758 173.865 1.00 66.66  ? 489 TYR B CD1 1 
ATOM   6667 C CD2 . TYR B 1 489 ? 149.944 166.296 171.535 1.00 66.66  ? 489 TYR B CD2 1 
ATOM   6668 C CE1 . TYR B 1 489 ? 149.885 165.409 174.141 1.00 66.66  ? 489 TYR B CE1 1 
ATOM   6669 C CE2 . TYR B 1 489 ? 150.015 164.947 171.801 1.00 66.66  ? 489 TYR B CE2 1 
ATOM   6670 C CZ  . TYR B 1 489 ? 149.985 164.508 173.104 1.00 66.66  ? 489 TYR B CZ  1 
ATOM   6671 O OH  . TYR B 1 489 ? 150.054 163.161 173.370 1.00 66.66  ? 489 TYR B OH  1 
ATOM   6672 N N   . GLY B 1 490 ? 152.449 169.068 170.574 1.00 63.16  ? 490 GLY B N   1 
ATOM   6673 C CA  . GLY B 1 490 ? 153.585 168.479 169.879 1.00 63.16  ? 490 GLY B CA  1 
ATOM   6674 C C   . GLY B 1 490 ? 154.922 169.035 170.334 1.00 63.16  ? 490 GLY B C   1 
ATOM   6675 O O   . GLY B 1 490 ? 155.961 168.365 170.212 1.00 63.16  ? 490 GLY B O   1 
ATOM   6676 N N   . LEU B 1 491 ? 154.922 170.265 170.854 1.00 61.05  ? 491 LEU B N   1 
ATOM   6677 C CA  . LEU B 1 491 ? 156.148 170.790 171.452 1.00 61.05  ? 491 LEU B CA  1 
ATOM   6678 C C   . LEU B 1 491 ? 156.660 169.888 172.575 1.00 61.05  ? 491 LEU B C   1 
ATOM   6679 O O   . LEU B 1 491 ? 157.877 169.753 172.762 1.00 61.05  ? 491 LEU B O   1 
ATOM   6680 C CB  . LEU B 1 491 ? 155.918 172.209 171.968 1.00 61.05  ? 491 LEU B CB  1 
ATOM   6681 C CG  . LEU B 1 491 ? 157.162 173.090 172.096 1.00 61.05  ? 491 LEU B CG  1 
ATOM   6682 C CD1 . LEU B 1 491 ? 157.950 173.103 170.801 1.00 61.05  ? 491 LEU B CD1 1 
ATOM   6683 C CD2 . LEU B 1 491 ? 156.777 174.499 172.497 1.00 61.05  ? 491 LEU B CD2 1 
ATOM   6684 N N   . LEU B 1 492 ? 155.753 169.246 173.317 1.00 61.84  ? 492 LEU B N   1 
ATOM   6685 C CA  . LEU B 1 492 ? 156.170 168.336 174.381 1.00 61.84  ? 492 LEU B CA  1 
ATOM   6686 C C   . LEU B 1 492 ? 156.886 167.111 173.822 1.00 61.84  ? 492 LEU B C   1 
ATOM   6687 O O   . LEU B 1 492 ? 157.857 166.627 174.416 1.00 61.84  ? 492 LEU B O   1 
ATOM   6688 C CB  . LEU B 1 492 ? 154.961 167.911 175.213 1.00 61.84  ? 492 LEU B CB  1 
ATOM   6689 C CG  . LEU B 1 492 ? 154.349 168.968 176.131 1.00 61.84  ? 492 LEU B CG  1 
ATOM   6690 C CD1 . LEU B 1 492 ? 153.018 168.488 176.676 1.00 61.84  ? 492 LEU B CD1 1 
ATOM   6691 C CD2 . LEU B 1 492 ? 155.299 169.309 177.262 1.00 61.84  ? 492 LEU B CD2 1 
ATOM   6692 N N   . TRP B 1 493 ? 156.410 166.583 172.695 1.00 62.80  ? 493 TRP B N   1 
ATOM   6693 C CA  . TRP B 1 493 ? 157.097 165.460 172.065 1.00 62.80  ? 493 TRP B CA  1 
ATOM   6694 C C   . TRP B 1 493 ? 158.479 165.869 171.579 1.00 62.80  ? 493 TRP B C   1 
ATOM   6695 O O   . TRP B 1 493 ? 159.437 165.089 171.672 1.00 62.80  ? 493 TRP B O   1 
ATOM   6696 C CB  . TRP B 1 493 ? 156.257 164.913 170.915 1.00 62.80  ? 493 TRP B CB  1 
ATOM   6697 C CG  . TRP B 1 493 ? 155.106 164.085 171.375 1.00 62.80  ? 493 TRP B CG  1 
ATOM   6698 C CD1 . TRP B 1 493 ? 154.050 164.499 172.129 1.00 62.80  ? 493 TRP B CD1 1 
ATOM   6699 C CD2 . TRP B 1 493 ? 154.896 162.693 171.119 1.00 62.80  ? 493 TRP B CD2 1 
ATOM   6700 N NE1 . TRP B 1 493 ? 153.192 163.453 172.357 1.00 62.80  ? 493 TRP B NE1 1 
ATOM   6701 C CE2 . TRP B 1 493 ? 153.689 162.332 171.747 1.00 62.80  ? 493 TRP B CE2 1 
ATOM   6702 C CE3 . TRP B 1 493 ? 155.610 161.717 170.418 1.00 62.80  ? 493 TRP B CE3 1 
ATOM   6703 C CZ2 . TRP B 1 493 ? 153.180 161.037 171.695 1.00 62.80  ? 493 TRP B CZ2 1 
ATOM   6704 C CZ3 . TRP B 1 493 ? 155.103 160.433 170.368 1.00 62.80  ? 493 TRP B CZ3 1 
ATOM   6705 C CH2 . TRP B 1 493 ? 153.900 160.105 171.002 1.00 62.80  ? 493 TRP B CH2 1 
ATOM   6706 N N   . VAL B 1 494 ? 158.603 167.092 171.059 1.00 60.86  ? 494 VAL B N   1 
ATOM   6707 C CA  . VAL B 1 494 ? 159.930 167.587 170.688 1.00 60.86  ? 494 VAL B CA  1 
ATOM   6708 C C   . VAL B 1 494 ? 160.843 167.634 171.912 1.00 60.86  ? 494 VAL B C   1 
ATOM   6709 O O   . VAL B 1 494 ? 162.021 167.250 171.849 1.00 60.86  ? 494 VAL B O   1 
ATOM   6710 C CB  . VAL B 1 494 ? 159.823 168.962 170.006 1.00 60.86  ? 494 VAL B CB  1 
ATOM   6711 C CG1 . VAL B 1 494 ? 161.196 169.440 169.579 1.00 60.86  ? 494 VAL B CG1 1 
ATOM   6712 C CG2 . VAL B 1 494 ? 158.894 168.887 168.811 1.00 60.86  ? 494 VAL B CG2 1 
ATOM   6713 N N   . ALA B 1 495 ? 160.312 168.098 173.046 1.00 59.84  ? 495 ALA B N   1 
ATOM   6714 C CA  . ALA B 1 495 ? 161.105 168.138 174.274 1.00 59.84  ? 495 ALA B CA  1 
ATOM   6715 C C   . ALA B 1 495 ? 161.534 166.740 174.712 1.00 59.84  ? 495 ALA B C   1 
ATOM   6716 O O   . ALA B 1 495 ? 162.664 166.543 175.177 1.00 59.84  ? 495 ALA B O   1 
ATOM   6717 C CB  . ALA B 1 495 ? 160.315 168.828 175.385 1.00 59.84  ? 495 ALA B CB  1 
ATOM   6718 N N   . GLY B 1 496 ? 160.638 165.760 174.593 1.00 59.31  ? 496 GLY B N   1 
ATOM   6719 C CA  . GLY B 1 496 ? 161.005 164.391 174.930 1.00 59.31  ? 496 GLY B CA  1 
ATOM   6720 C C   . GLY B 1 496 ? 162.102 163.844 174.035 1.00 59.31  ? 496 GLY B C   1 
ATOM   6721 O O   . GLY B 1 496 ? 163.007 163.138 174.496 1.00 59.31  ? 496 GLY B O   1 
ATOM   6722 N N   . ALA B 1 497 ? 162.040 164.166 172.741 1.00 59.78  ? 497 ALA B N   1 
ATOM   6723 C CA  . ALA B 1 497 ? 163.122 163.784 171.839 1.00 59.78  ? 497 ALA B CA  1 
ATOM   6724 C C   . ALA B 1 497 ? 164.441 164.416 172.268 1.00 59.78  ? 497 ALA B C   1 
ATOM   6725 O O   . ALA B 1 497 ? 165.496 163.775 172.208 1.00 59.78  ? 497 ALA B O   1 
ATOM   6726 C CB  . ALA B 1 497 ? 162.777 164.176 170.404 1.00 59.78  ? 497 ALA B CB  1 
ATOM   6727 N N   . ALA B 1 498 ? 164.400 165.678 172.703 1.00 59.17  ? 498 ALA B N   1 
ATOM   6728 C CA  . ALA B 1 498 ? 165.617 166.325 173.194 1.00 59.17  ? 498 ALA B CA  1 
ATOM   6729 C C   . ALA B 1 498 ? 166.158 165.628 174.439 1.00 59.17  ? 498 ALA B C   1 
ATOM   6730 O O   . ALA B 1 498 ? 167.378 165.507 174.615 1.00 59.17  ? 498 ALA B O   1 
ATOM   6731 C CB  . ALA B 1 498 ? 165.353 167.799 173.480 1.00 59.17  ? 498 ALA B CB  1 
ATOM   6732 N N   . ILE B 1 499 ? 165.267 165.186 175.329 1.00 60.65  ? 499 ILE B N   1 
ATOM   6733 C CA  . ILE B 1 499 ? 165.707 164.429 176.501 1.00 60.65  ? 499 ILE B CA  1 
ATOM   6734 C C   . ILE B 1 499 ? 166.411 163.147 176.073 1.00 60.65  ? 499 ILE B C   1 
ATOM   6735 O O   . ILE B 1 499 ? 167.438 162.759 176.647 1.00 60.65  ? 499 ILE B O   1 
ATOM   6736 C CB  . ILE B 1 499 ? 164.521 164.127 177.435 1.00 60.65  ? 499 ILE B CB  1 
ATOM   6737 C CG1 . ILE B 1 499 ? 163.917 165.415 177.985 1.00 60.65  ? 499 ILE B CG1 1 
ATOM   6738 C CG2 . ILE B 1 499 ? 164.955 163.226 178.576 1.00 60.65  ? 499 ILE B CG2 1 
ATOM   6739 C CD1 . ILE B 1 499 ? 162.603 165.196 178.695 1.00 60.65  ? 499 ILE B CD1 1 
ATOM   6740 N N   . ILE B 1 500 ? 165.857 162.460 175.071 1.00 60.78  ? 500 ILE B N   1 
ATOM   6741 C CA  . ILE B 1 500 ? 166.510 161.258 174.555 1.00 60.78  ? 500 ILE B CA  1 
ATOM   6742 C C   . ILE B 1 500 ? 167.888 161.598 173.995 1.00 60.78  ? 500 ILE B C   1 
ATOM   6743 O O   . ILE B 1 500 ? 168.854 160.847 174.182 1.00 60.78  ? 500 ILE B O   1 
ATOM   6744 C CB  . ILE B 1 500 ? 165.620 160.572 173.501 1.00 60.78  ? 500 ILE B CB  1 
ATOM   6745 C CG1 . ILE B 1 500 ? 164.398 159.941 174.166 1.00 60.78  ? 500 ILE B CG1 1 
ATOM   6746 C CG2 . ILE B 1 500 ? 166.401 159.513 172.748 1.00 60.78  ? 500 ILE B CG2 1 
ATOM   6747 C CD1 . ILE B 1 500 ? 163.556 159.113 173.225 1.00 60.78  ? 500 ILE B CD1 1 
ATOM   6748 N N   . VAL B 1 501 ? 168.000 162.737 173.306 1.00 61.19  ? 501 VAL B N   1 
ATOM   6749 C CA  . VAL B 1 501 ? 169.293 163.162 172.767 1.00 61.19  ? 501 VAL B CA  1 
ATOM   6750 C C   . VAL B 1 501 ? 170.304 163.353 173.889 1.00 61.19  ? 501 VAL B C   1 
ATOM   6751 O O   . VAL B 1 501 ? 171.463 162.940 173.778 1.00 61.19  ? 501 VAL B O   1 
ATOM   6752 C CB  . VAL B 1 501 ? 169.143 164.452 171.939 1.00 61.19  ? 501 VAL B CB  1 
ATOM   6753 C CG1 . VAL B 1 501 ? 170.505 164.943 171.484 1.00 61.19  ? 501 VAL B CG1 1 
ATOM   6754 C CG2 . VAL B 1 501 ? 168.246 164.227 170.753 1.00 61.19  ? 501 VAL B CG2 1 
ATOM   6755 N N   . GLY B 1 502 ? 169.888 164.005 174.974 1.00 63.71  ? 502 GLY B N   1 
ATOM   6756 C CA  . GLY B 1 502 ? 170.799 164.213 176.091 1.00 63.71  ? 502 GLY B CA  1 
ATOM   6757 C C   . GLY B 1 502 ? 171.221 162.915 176.754 1.00 63.71  ? 502 GLY B C   1 
ATOM   6758 O O   . GLY B 1 502 ? 172.397 162.723 177.082 1.00 63.71  ? 502 GLY B O   1 
ATOM   6759 N N   . GLY B 1 503 ? 170.267 162.006 176.960 1.00 63.52  ? 503 GLY B N   1 
ATOM   6760 C CA  . GLY B 1 503 ? 170.612 160.708 177.516 1.00 63.52  ? 503 GLY B CA  1 
ATOM   6761 C C   . GLY B 1 503 ? 171.582 159.943 176.636 1.00 63.52  ? 503 GLY B C   1 
ATOM   6762 O O   . GLY B 1 503 ? 172.461 159.235 177.131 1.00 63.52  ? 503 GLY B O   1 
ATOM   6763 N N   . MET B 1 504 ? 171.432 160.073 175.317 1.00 64.47  ? 504 MET B N   1 
ATOM   6764 C CA  . MET B 1 504 ? 172.358 159.423 174.395 1.00 64.47  ? 504 MET B CA  1 
ATOM   6765 C C   . MET B 1 504 ? 173.739 160.066 174.445 1.00 64.47  ? 504 MET B C   1 
ATOM   6766 O O   . MET B 1 504 ? 174.757 159.366 174.421 1.00 64.47  ? 504 MET B O   1 
ATOM   6767 C CB  . MET B 1 504 ? 171.790 159.473 172.979 1.00 64.47  ? 504 MET B CB  1 
ATOM   6768 C CG  . MET B 1 504 ? 172.599 158.727 171.946 1.00 64.47  ? 504 MET B CG  1 
ATOM   6769 S SD  . MET B 1 504 ? 171.831 158.845 170.324 1.00 64.47  ? 504 MET B SD  1 
ATOM   6770 C CE  . MET B 1 504 ? 170.410 157.784 170.551 1.00 64.47  ? 504 MET B CE  1 
ATOM   6771 N N   . ALA B 1 505 ? 173.794 161.397 174.513 1.00 63.58  ? 505 ALA B N   1 
ATOM   6772 C CA  . ALA B 1 505 ? 175.065 162.109 174.563 1.00 63.58  ? 505 ALA B CA  1 
ATOM   6773 C C   . ALA B 1 505 ? 175.763 161.977 175.907 1.00 63.58  ? 505 ALA B C   1 
ATOM   6774 O O   . ALA B 1 505 ? 176.927 162.369 176.024 1.00 63.58  ? 505 ALA B O   1 
ATOM   6775 C CB  . ALA B 1 505 ? 174.855 163.589 174.241 1.00 63.58  ? 505 ALA B CB  1 
ATOM   6776 N N   . LEU B 1 506 ? 175.077 161.459 176.922 1.00 63.31  ? 506 LEU B N   1 
ATOM   6777 C CA  . LEU B 1 506 ? 175.717 161.203 178.209 1.00 63.31  ? 506 LEU B CA  1 
ATOM   6778 C C   . LEU B 1 506 ? 176.787 160.107 178.145 1.00 63.31  ? 506 LEU B C   1 
ATOM   6779 O O   . LEU B 1 506 ? 177.411 159.820 179.171 1.00 63.31  ? 506 LEU B O   1 
ATOM   6780 C CB  . LEU B 1 506 ? 174.640 160.840 179.236 1.00 63.31  ? 506 LEU B CB  1 
ATOM   6781 C CG  . LEU B 1 506 ? 174.959 160.743 180.727 1.00 63.31  ? 506 LEU B CG  1 
ATOM   6782 C CD1 . LEU B 1 506 ? 175.421 162.087 181.257 1.00 63.31  ? 506 LEU B CD1 1 
ATOM   6783 C CD2 . LEU B 1 506 ? 173.739 160.261 181.490 1.00 63.31  ? 506 LEU B CD2 1 
ATOM   6784 N N   . PHE B 1 507 ? 177.036 159.505 176.977 1.00 64.68  ? 507 PHE B N   1 
ATOM   6785 C CA  . PHE B 1 507 ? 177.953 158.377 176.840 1.00 64.68  ? 507 PHE B CA  1 
ATOM   6786 C C   . PHE B 1 507 ? 179.106 158.673 175.884 1.00 64.68  ? 507 PHE B C   1 
ATOM   6787 O O   . PHE B 1 507 ? 179.642 157.756 175.260 1.00 64.68  ? 507 PHE B O   1 
ATOM   6788 C CB  . PHE B 1 507 ? 177.207 157.132 176.361 1.00 64.68  ? 507 PHE B CB  1 
ATOM   6789 C CG  . PHE B 1 507 ? 176.395 156.454 177.424 1.00 64.68  ? 507 PHE B CG  1 
ATOM   6790 C CD1 . PHE B 1 507 ? 176.978 155.540 178.282 1.00 64.68  ? 507 PHE B CD1 1 
ATOM   6791 C CD2 . PHE B 1 507 ? 175.043 156.718 177.552 1.00 64.68  ? 507 PHE B CD2 1 
ATOM   6792 C CE1 . PHE B 1 507 ? 176.230 154.911 179.256 1.00 64.68  ? 507 PHE B CE1 1 
ATOM   6793 C CE2 . PHE B 1 507 ? 174.292 156.092 178.524 1.00 64.68  ? 507 PHE B CE2 1 
ATOM   6794 C CZ  . PHE B 1 507 ? 174.886 155.187 179.376 1.00 64.68  ? 507 PHE B CZ  1 
ATOM   6795 N N   . ILE B 1 508 ? 179.509 159.936 175.751 1.00 62.47  ? 508 ILE B N   1 
ATOM   6796 C CA  . ILE B 1 508 ? 180.505 160.290 174.741 1.00 62.47  ? 508 ILE B CA  1 
ATOM   6797 C C   . ILE B 1 508 ? 181.905 159.884 175.190 1.00 62.47  ? 508 ILE B C   1 
ATOM   6798 O O   . ILE B 1 508 ? 182.557 159.044 174.559 1.00 62.47  ? 508 ILE B O   1 
ATOM   6799 C CB  . ILE B 1 508 ? 180.433 161.791 174.409 1.00 62.47  ? 508 ILE B CB  1 
ATOM   6800 C CG1 . ILE B 1 508 ? 179.096 162.125 173.750 1.00 62.47  ? 508 ILE B CG1 1 
ATOM   6801 C CG2 . ILE B 1 508 ? 181.577 162.188 173.497 1.00 62.47  ? 508 ILE B CG2 1 
ATOM   6802 C CD1 . ILE B 1 508 ? 178.960 161.595 172.349 1.00 62.47  ? 508 ILE B CD1 1 
ATOM   6803 N N   . GLY B 1 509 ? 182.389 160.468 176.281 1.00 59.99  ? 509 GLY B N   1 
ATOM   6804 C CA  . GLY B 1 509 ? 183.668 160.078 176.834 1.00 59.99  ? 509 GLY B CA  1 
ATOM   6805 C C   . GLY B 1 509 ? 184.888 160.738 176.228 1.00 59.99  ? 509 GLY B C   1 
ATOM   6806 O O   . GLY B 1 509 ? 186.011 160.362 176.587 1.00 59.99  ? 509 GLY B O   1 
ATOM   6807 N N   . TYR B 1 510 ? 184.718 161.697 175.323 1.00 59.11  ? 510 TYR B N   1 
ATOM   6808 C CA  . TYR B 1 510 ? 185.860 162.418 174.777 1.00 59.11  ? 510 TYR B CA  1 
ATOM   6809 C C   . TYR B 1 510 ? 186.395 163.403 175.808 1.00 59.11  ? 510 TYR B C   1 
ATOM   6810 O O   . TYR B 1 510 ? 185.632 164.173 176.397 1.00 59.11  ? 510 TYR B O   1 
ATOM   6811 C CB  . TYR B 1 510 ? 185.461 163.165 173.505 1.00 59.11  ? 510 TYR B CB  1 
ATOM   6812 C CG  . TYR B 1 510 ? 185.610 162.371 172.231 1.00 59.11  ? 510 TYR B CG  1 
ATOM   6813 C CD1 . TYR B 1 510 ? 186.825 161.805 171.880 1.00 59.11  ? 510 TYR B CD1 1 
ATOM   6814 C CD2 . TYR B 1 510 ? 184.537 162.197 171.371 1.00 59.11  ? 510 TYR B CD2 1 
ATOM   6815 C CE1 . TYR B 1 510 ? 186.965 161.083 170.713 1.00 59.11  ? 510 TYR B CE1 1 
ATOM   6816 C CE2 . TYR B 1 510 ? 184.667 161.478 170.204 1.00 59.11  ? 510 TYR B CE2 1 
ATOM   6817 C CZ  . TYR B 1 510 ? 185.882 160.923 169.879 1.00 59.11  ? 510 TYR B CZ  1 
ATOM   6818 O OH  . TYR B 1 510 ? 186.015 160.205 168.716 1.00 59.11  ? 510 TYR B OH  1 
ATOM   6819 N N   . THR B 1 511 ? 187.703 163.379 176.029 1.00 58.02  ? 511 THR B N   1 
ATOM   6820 C CA  . THR B 1 511 ? 188.324 164.347 176.915 1.00 58.02  ? 511 THR B CA  1 
ATOM   6821 C C   . THR B 1 511 ? 188.633 165.633 176.156 1.00 58.02  ? 511 THR B C   1 
ATOM   6822 O O   . THR B 1 511 ? 188.791 165.619 174.934 1.00 58.02  ? 511 THR B O   1 
ATOM   6823 C CB  . THR B 1 511 ? 189.601 163.772 177.521 1.00 58.02  ? 511 THR B CB  1 
ATOM   6824 O OG1 . THR B 1 511 ? 190.536 163.470 176.480 1.00 58.02  ? 511 THR B OG1 1 
ATOM   6825 C CG2 . THR B 1 511 ? 189.299 162.509 178.305 1.00 58.02  ? 511 THR B CG2 1 
ATOM   6826 N N   . PRO B 1 512 ? 188.710 166.767 176.858 1.00 57.70  ? 512 PRO B N   1 
ATOM   6827 C CA  . PRO B 1 512 ? 189.070 168.020 176.175 1.00 57.70  ? 512 PRO B CA  1 
ATOM   6828 C C   . PRO B 1 512 ? 190.432 167.976 175.509 1.00 57.70  ? 512 PRO B C   1 
ATOM   6829 O O   . PRO B 1 512 ? 190.654 168.691 174.526 1.00 57.70  ? 512 PRO B O   1 
ATOM   6830 C CB  . PRO B 1 512 ? 189.029 169.057 177.305 1.00 57.70  ? 512 PRO B CB  1 
ATOM   6831 C CG  . PRO B 1 512 ? 188.131 168.470 178.325 1.00 57.70  ? 512 PRO B CG  1 
ATOM   6832 C CD  . PRO B 1 512 ? 188.348 166.993 178.267 1.00 57.70  ? 512 PRO B CD  1 
ATOM   6833 N N   . GLN B 1 513 ? 191.355 167.157 176.016 1.00 59.53  ? 513 GLN B N   1 
ATOM   6834 C CA  . GLN B 1 513 ? 192.682 167.063 175.421 1.00 59.53  ? 513 GLN B CA  1 
ATOM   6835 C C   . GLN B 1 513 ? 192.660 166.408 174.048 1.00 59.53  ? 513 GLN B C   1 
ATOM   6836 O O   . GLN B 1 513 ? 193.639 166.527 173.305 1.00 59.53  ? 513 GLN B O   1 
ATOM   6837 C CB  . GLN B 1 513 ? 193.624 166.285 176.342 1.00 59.53  ? 513 GLN B CB  1 
ATOM   6838 C CG  . GLN B 1 513 ? 194.061 167.031 177.599 1.00 59.53  ? 513 GLN B CG  1 
ATOM   6839 C CD  . GLN B 1 513 ? 192.937 167.227 178.600 1.00 59.53  ? 513 GLN B CD  1 
ATOM   6840 O OE1 . GLN B 1 513 ? 192.582 168.355 178.939 1.00 59.53  ? 513 GLN B OE1 1 
ATOM   6841 N NE2 . GLN B 1 513 ? 192.375 166.125 179.081 1.00 59.53  ? 513 GLN B NE2 1 
ATOM   6842 N N   . GLN B 1 514 ? 191.577 165.718 173.696 1.00 57.86  ? 514 GLN B N   1 
ATOM   6843 C CA  . GLN B 1 514 ? 191.487 165.010 172.426 1.00 57.86  ? 514 GLN B CA  1 
ATOM   6844 C C   . GLN B 1 514 ? 190.817 165.817 171.327 1.00 57.86  ? 514 GLN B C   1 
ATOM   6845 O O   . GLN B 1 514 ? 191.074 165.562 170.147 1.00 57.86  ? 514 GLN B O   1 
ATOM   6846 C CB  . GLN B 1 514 ? 190.721 163.695 172.604 1.00 57.86  ? 514 GLN B CB  1 
ATOM   6847 C CG  . GLN B 1 514 ? 191.422 162.673 173.473 1.00 57.86  ? 514 GLN B CG  1 
ATOM   6848 C CD  . GLN B 1 514 ? 190.542 161.482 173.790 1.00 57.86  ? 514 GLN B CD  1 
ATOM   6849 O OE1 . GLN B 1 514 ? 190.495 161.015 174.926 1.00 57.86  ? 514 GLN B OE1 1 
ATOM   6850 N NE2 . GLN B 1 514 ? 189.837 160.985 172.783 1.00 57.86  ? 514 GLN B NE2 1 
ATOM   6851 N N   . VAL B 1 515 ? 189.965 166.779 171.676 1.00 54.13  ? 515 VAL B N   1 
ATOM   6852 C CA  . VAL B 1 515 ? 189.174 167.489 170.688 1.00 54.13  ? 515 VAL B CA  1 
ATOM   6853 C C   . VAL B 1 515 ? 189.575 168.955 170.543 1.00 54.13  ? 515 VAL B C   1 
ATOM   6854 O O   . VAL B 1 515 ? 189.519 169.487 169.428 1.00 54.13  ? 515 VAL B O   1 
ATOM   6855 C CB  . VAL B 1 515 ? 187.667 167.365 171.000 1.00 54.13  ? 515 VAL B CB  1 
ATOM   6856 C CG1 . VAL B 1 515 ? 187.223 165.923 170.874 1.00 54.13  ? 515 VAL B CG1 1 
ATOM   6857 C CG2 . VAL B 1 515 ? 187.357 167.888 172.384 1.00 54.13  ? 515 VAL B CG2 1 
ATOM   6858 N N   . ALA B 1 516 ? 189.981 169.627 171.622 1.00 55.06  ? 516 ALA B N   1 
ATOM   6859 C CA  . ALA B 1 516 ? 190.178 171.071 171.579 1.00 55.06  ? 516 ALA B CA  1 
ATOM   6860 C C   . ALA B 1 516 ? 191.510 171.493 172.186 1.00 55.06  ? 516 ALA B C   1 
ATOM   6861 O O   . ALA B 1 516 ? 191.612 172.574 172.769 1.00 55.06  ? 516 ALA B O   1 
ATOM   6862 C CB  . ALA B 1 516 ? 189.029 171.792 172.280 1.00 55.06  ? 516 ALA B CB  1 
ATOM   6863 N N   . HIS B 1 517 ? 192.545 170.668 172.052 1.00 60.33  ? 517 HIS B N   1 
ATOM   6864 C CA  . HIS B 1 517 ? 193.862 171.012 172.570 1.00 60.33  ? 517 HIS B CA  1 
ATOM   6865 C C   . HIS B 1 517 ? 194.912 170.728 171.510 1.00 60.33  ? 517 HIS B C   1 
ATOM   6866 O O   . HIS B 1 517 ? 194.901 169.660 170.893 1.00 60.33  ? 517 HIS B O   1 
ATOM   6867 C CB  . HIS B 1 517 ? 194.181 170.235 173.851 1.00 60.33  ? 517 HIS B CB  1 
ATOM   6868 C CG  . HIS B 1 517 ? 193.688 170.899 175.099 1.00 60.33  ? 517 HIS B CG  1 
ATOM   6869 N ND1 . HIS B 1 517 ? 193.486 170.214 176.276 1.00 60.33  ? 517 HIS B ND1 1 
ATOM   6870 C CD2 . HIS B 1 517 ? 193.352 172.186 175.350 1.00 60.33  ? 517 HIS B CD2 1 
ATOM   6871 C CE1 . HIS B 1 517 ? 193.049 171.050 177.200 1.00 60.33  ? 517 HIS B CE1 1 
ATOM   6872 N NE2 . HIS B 1 517 ? 192.958 172.253 176.664 1.00 60.33  ? 517 HIS B NE2 1 
ATOM   6873 N N   . ALA B 1 518 ? 195.816 171.682 171.308 1.00 69.34  ? 518 ALA B N   1 
ATOM   6874 C CA  . ALA B 1 518 ? 196.885 171.525 170.333 1.00 69.34  ? 518 ALA B CA  1 
ATOM   6875 C C   . ALA B 1 518 ? 198.019 170.694 170.914 1.00 69.34  ? 518 ALA B C   1 
ATOM   6876 O O   . ALA B 1 518 ? 198.377 170.838 172.087 1.00 69.34  ? 518 ALA B O   1 
ATOM   6877 C CB  . ALA B 1 518 ? 197.413 172.890 169.894 1.00 69.34  ? 518 ALA B CB  1 
ATOM   6878 N N   . GLN B 1 519 ? 198.588 169.825 170.086 1.00 79.63  ? 519 GLN B N   1 
ATOM   6879 C CA  . GLN B 1 519 ? 199.714 169.003 170.510 1.00 79.63  ? 519 GLN B CA  1 
ATOM   6880 C C   . GLN B 1 519 ? 201.035 169.723 170.254 1.00 79.63  ? 519 GLN B C   1 
ATOM   6881 O O   . GLN B 1 519 ? 201.999 169.556 171.001 1.00 79.63  ? 519 GLN B O   1 
ATOM   6882 C CB  . GLN B 1 519 ? 199.703 167.655 169.789 1.00 79.63  ? 519 GLN B CB  1 
ATOM   6883 C CG  . GLN B 1 519 ? 200.078 167.734 168.321 1.00 79.63  ? 519 GLN B CG  1 
ATOM   6884 C CD  . GLN B 1 519 ? 200.194 166.367 167.678 1.00 79.63  ? 519 GLN B CD  1 
ATOM   6885 O OE1 . GLN B 1 519 ? 200.020 165.342 168.336 1.00 79.63  ? 519 GLN B OE1 1 
ATOM   6886 N NE2 . GLN B 1 519 ? 200.494 166.345 166.384 1.00 79.63  ? 519 GLN B NE2 1 
HETATM 6887 C C4  . Y86 C 2 .   ? 165.009 167.885 204.024 1.00 65.16  ? 601 Y86 A C4  1 
HETATM 6888 C C5  . Y86 C 2 .   ? 164.265 167.659 205.301 1.00 65.16  ? 601 Y86 A C5  1 
HETATM 6889 C C6  . Y86 C 2 .   ? 164.215 166.245 205.786 1.00 65.16  ? 601 Y86 A C6  1 
HETATM 6890 C C7  . Y86 C 2 .   ? 163.716 165.852 206.938 1.00 65.16  ? 601 Y86 A C7  1 
HETATM 6891 C C8  . Y86 C 2 .   ? 163.322 166.748 208.071 1.00 65.16  ? 601 Y86 A C8  1 
HETATM 6892 C C10 . Y86 C 2 .   ? 164.768 168.627 208.915 1.00 65.16  ? 601 Y86 A C10 1 
HETATM 6893 C C13 . Y86 C 2 .   ? 165.806 171.509 207.906 1.00 65.16  ? 601 Y86 A C13 1 
HETATM 6894 C C15 . Y86 C 2 .   ? 166.594 172.540 205.719 1.00 65.16  ? 601 Y86 A C15 1 
HETATM 6895 C C17 . Y86 C 2 .   ? 168.956 172.648 204.854 1.00 65.16  ? 601 Y86 A C17 1 
HETATM 6896 C C20 . Y86 C 2 .   ? 172.456 175.680 205.754 1.00 65.16  ? 601 Y86 A C20 1 
HETATM 6897 C C21 . Y86 C 2 .   ? 173.338 177.397 204.321 1.00 65.16  ? 601 Y86 A C21 1 
HETATM 6898 C C22 . Y86 C 2 .   ? 173.950 178.770 204.252 1.00 65.16  ? 601 Y86 A C22 1 
HETATM 6899 C C24 . Y86 C 2 .   ? 175.323 178.620 202.136 1.00 65.16  ? 601 Y86 A C24 1 
HETATM 6900 C C26 . Y86 C 2 .   ? 174.225 177.438 200.194 1.00 65.16  ? 601 Y86 A C26 1 
HETATM 6901 C C28 . Y86 C 2 .   ? 174.252 177.881 197.681 1.00 65.16  ? 601 Y86 A C28 1 
HETATM 6902 C C1  . Y86 C 2 .   ? 168.100 169.143 202.869 1.00 65.16  ? 601 Y86 A C1  1 
HETATM 6903 C C11 . Y86 C 2 .   ? 163.991 169.774 208.348 1.00 65.16  ? 601 Y86 A C11 1 
HETATM 6904 C C12 . Y86 C 2 .   ? 164.569 171.111 208.695 1.00 65.16  ? 601 Y86 A C12 1 
HETATM 6905 C C14 . Y86 C 2 .   ? 165.556 171.705 206.432 1.00 65.16  ? 601 Y86 A C14 1 
HETATM 6906 C C16 . Y86 C 2 .   ? 168.021 172.027 205.849 1.00 65.16  ? 601 Y86 A C16 1 
HETATM 6907 C C18 . Y86 C 2 .   ? 169.244 174.106 205.093 1.00 65.16  ? 601 Y86 A C18 1 
HETATM 6908 C C19 . Y86 C 2 .   ? 170.997 175.671 205.351 1.00 65.16  ? 601 Y86 A C19 1 
HETATM 6909 C C2  . Y86 C 2 .   ? 167.080 168.090 202.621 1.00 65.16  ? 601 Y86 A C2  1 
HETATM 6910 C C23 . Y86 C 2 .   ? 174.144 179.264 202.849 1.00 65.16  ? 601 Y86 A C23 1 
HETATM 6911 C C25 . Y86 C 2 .   ? 175.157 178.540 200.636 1.00 65.16  ? 601 Y86 A C25 1 
HETATM 6912 C C27 . Y86 C 2 .   ? 173.438 177.724 198.938 1.00 65.16  ? 601 Y86 A C27 1 
HETATM 6913 C C29 . Y86 C 2 .   ? 173.412 178.121 196.450 1.00 65.16  ? 601 Y86 A C29 1 
HETATM 6914 C C3  . Y86 C 2 .   ? 166.309 167.730 203.853 1.00 65.16  ? 601 Y86 A C3  1 
HETATM 6915 C C30 . Y86 C 2 .   ? 174.201 178.360 195.188 1.00 65.16  ? 601 Y86 A C30 1 
HETATM 6916 C C31 . Y86 C 2 .   ? 175.011 177.178 194.727 1.00 65.16  ? 601 Y86 A C31 1 
HETATM 6917 C C32 . Y86 C 2 .   ? 175.964 177.488 193.603 1.00 65.16  ? 601 Y86 A C32 1 
HETATM 6918 C C33 . Y86 C 2 .   ? 176.890 178.641 193.895 1.00 65.16  ? 601 Y86 A C33 1 
HETATM 6919 C C34 . Y86 C 2 .   ? 178.149 178.649 193.070 1.00 65.16  ? 601 Y86 A C34 1 
HETATM 6920 C C35 . Y86 C 2 .   ? 179.121 179.740 193.441 1.00 65.16  ? 601 Y86 A C35 1 
HETATM 6921 C C36 . Y86 C 2 .   ? 180.546 179.449 193.044 1.00 65.16  ? 601 Y86 A C36 1 
HETATM 6922 C C37 . Y86 C 2 .   ? 181.097 178.190 193.665 1.00 65.16  ? 601 Y86 A C37 1 
HETATM 6923 C C38 . Y86 C 2 .   ? 182.531 177.849 193.366 1.00 65.16  ? 601 Y86 A C38 1 
HETATM 6924 C C39 . Y86 C 2 .   ? 182.987 176.603 194.087 1.00 65.16  ? 601 Y86 A C39 1 
HETATM 6925 C C40 . Y86 C 2 .   ? 172.687 175.255 207.187 1.00 65.16  ? 601 Y86 A C40 1 
HETATM 6926 C C9  . Y86 C 2 .   ? 164.484 167.340 208.807 1.00 65.16  ? 601 Y86 A C9  1 
HETATM 6927 O O1  . Y86 C 2 .   ? 170.534 174.303 205.346 1.00 65.16  ? 601 Y86 A O1  1 
HETATM 6928 O O2  . Y86 C 2 .   ? 173.048 176.997 205.569 1.00 65.16  ? 601 Y86 A O2  1 
HETATM 6929 O O3  . Y86 C 2 .   ? 173.129 176.706 203.361 1.00 65.16  ? 601 Y86 A O3  1 
HETATM 6930 O O4  . Y86 C 2 .   ? 172.290 173.873 207.418 1.00 65.16  ? 601 Y86 A O4  1 
HETATM 6931 O O5  . Y86 C 2 .   ? 174.620 172.973 207.436 1.00 65.16  ? 601 Y86 A O5  1 
HETATM 6932 O O6  . Y86 C 2 .   ? 172.643 171.407 207.467 1.00 65.16  ? 601 Y86 A O6  1 
HETATM 6933 O O7  . Y86 C 2 .   ? 173.183 172.707 205.375 1.00 65.16  ? 601 Y86 A O7  1 
HETATM 6934 O O8  . Y86 C 2 .   ? 168.436 174.995 205.056 1.00 65.16  ? 601 Y86 A O8  1 
HETATM 6935 P P1  . Y86 C 2 .   ? 173.238 172.676 206.889 1.00 65.16  ? 601 Y86 A P1  1 
HETATM 6936 C C1  . Y8F D 3 .   ? 168.957 166.895 182.908 1.00 68.57  ? 602 Y8F A C1  1 
HETATM 6937 C C2  . Y8F D 3 .   ? 169.751 165.731 182.354 1.00 68.57  ? 602 Y8F A C2  1 
HETATM 6938 C C3  . Y8F D 3 .   ? 168.570 167.744 185.139 1.00 68.57  ? 602 Y8F A C3  1 
HETATM 6939 C C4  . Y8F D 3 .   ? 169.167 167.792 186.513 1.00 68.57  ? 602 Y8F A C4  1 
HETATM 6940 C C5  . Y8F D 3 .   ? 168.334 167.149 187.604 1.00 68.57  ? 602 Y8F A C5  1 
HETATM 6941 C C6  . Y8F D 3 .   ? 167.057 167.913 187.888 1.00 68.57  ? 602 Y8F A C6  1 
HETATM 6942 P P1  . Y8F D 3 .   ? 169.755 163.107 182.199 1.00 68.57  ? 602 Y8F A P1  1 
HETATM 6943 O O1  . Y8F D 3 .   ? 169.265 164.487 182.889 1.00 68.57  ? 602 Y8F A O1  1 
HETATM 6944 O O2  . Y8F D 3 .   ? 171.271 163.104 182.302 1.00 68.57  ? 602 Y8F A O2  1 
HETATM 6945 O O3  . Y8F D 3 .   ? 169.260 163.182 180.763 1.00 68.57  ? 602 Y8F A O3  1 
HETATM 6946 O O4  . Y8F D 3 .   ? 169.101 161.989 182.995 1.00 68.57  ? 602 Y8F A O4  1 
HETATM 6947 O O5  . Y8F D 3 .   ? 169.329 167.011 184.312 1.00 68.57  ? 602 Y8F A O5  1 
HETATM 6948 O O6  . Y8F D 3 .   ? 167.547 168.279 184.797 1.00 68.57  ? 602 Y8F A O6  1 
HETATM 6949 O O7  . Y8F D 3 .   ? 169.568 167.863 180.800 1.00 68.57  ? 602 Y8F A O7  1 
HETATM 6950 O O8  . Y8F D 3 .   ? 167.378 167.798 180.317 1.00 68.57  ? 602 Y8F A O8  1 
HETATM 6951 C C10 . Y8F D 3 .   ? 167.192 167.404 192.518 1.00 68.57  ? 602 Y8F A C10 1 
HETATM 6952 C C11 . Y8F D 3 .   ? 166.717 167.695 193.936 1.00 68.57  ? 602 Y8F A C11 1 
HETATM 6953 C C12 . Y8F D 3 .   ? 167.768 168.282 194.868 1.00 68.57  ? 602 Y8F A C12 1 
HETATM 6954 C C13 . Y8F D 3 .   ? 167.233 168.682 196.237 1.00 68.57  ? 602 Y8F A C13 1 
HETATM 6955 C C14 . Y8F D 3 .   ? 168.257 169.306 197.171 1.00 68.57  ? 602 Y8F A C14 1 
HETATM 6956 C C15 . Y8F D 3 .   ? 167.693 169.748 198.504 1.00 68.57  ? 602 Y8F A C15 1 
HETATM 6957 C C16 . Y8F D 3 .   ? 169.275 168.186 182.177 1.00 68.57  ? 602 Y8F A C16 1 
HETATM 6958 C C17 . Y8F D 3 .   ? 168.524 167.614 179.998 1.00 68.57  ? 602 Y8F A C17 1 
HETATM 6959 C C18 . Y8F D 3 .   ? 168.998 167.093 178.675 1.00 68.57  ? 602 Y8F A C18 1 
HETATM 6960 C C19 . Y8F D 3 .   ? 168.683 167.967 177.480 1.00 68.57  ? 602 Y8F A C19 1 
HETATM 6961 C C20 . Y8F D 3 .   ? 169.491 167.456 176.299 1.00 68.57  ? 602 Y8F A C20 1 
HETATM 6962 C C21 . Y8F D 3 .   ? 169.408 168.204 174.977 1.00 68.57  ? 602 Y8F A C21 1 
HETATM 6963 C C22 . Y8F D 3 .   ? 170.450 167.701 173.989 1.00 68.57  ? 602 Y8F A C22 1 
HETATM 6964 C C23 . Y8F D 3 .   ? 170.507 168.435 172.657 1.00 68.57  ? 602 Y8F A C23 1 
HETATM 6965 C C24 . Y8F D 3 .   ? 170.718 169.936 172.790 1.00 68.57  ? 602 Y8F A C24 1 
HETATM 6966 C C25 . Y8F D 3 .   ? 170.996 170.641 171.470 1.00 68.57  ? 602 Y8F A C25 1 
HETATM 6967 C C26 . Y8F D 3 .   ? 170.004 170.328 170.359 1.00 68.57  ? 602 Y8F A C26 1 
HETATM 6968 C C27 . Y8F D 3 .   ? 170.266 171.111 169.086 1.00 68.57  ? 602 Y8F A C27 1 
HETATM 6969 C C28 . Y8F D 3 .   ? 171.697 171.000 168.614 1.00 68.57  ? 602 Y8F A C28 1 
HETATM 6970 C C7  . Y8F D 3 .   ? 166.726 168.036 189.369 1.00 68.57  ? 602 Y8F A C7  1 
HETATM 6971 C C8  . Y8F D 3 .   ? 166.453 166.745 190.126 1.00 68.57  ? 602 Y8F A C8  1 
HETATM 6972 C C9  . Y8F D 3 .   ? 166.073 166.960 191.586 1.00 68.57  ? 602 Y8F A C9  1 
HETATM 6973 C C4  . Y86 E 2 .   ? 175.261 169.260 164.857 1.00 62.57  ? 601 Y86 B C4  1 
HETATM 6974 C C5  . Y86 E 2 .   ? 176.414 169.285 163.907 1.00 62.57  ? 601 Y86 B C5  1 
HETATM 6975 C C6  . Y86 E 2 .   ? 177.137 167.984 163.753 1.00 62.57  ? 601 Y86 B C6  1 
HETATM 6976 C C7  . Y86 E 2 .   ? 178.021 167.694 162.818 1.00 62.57  ? 601 Y86 B C7  1 
HETATM 6977 C C8  . Y86 E 2 .   ? 178.414 168.571 161.668 1.00 62.57  ? 601 Y86 B C8  1 
HETATM 6978 C C10 . Y86 E 2 .   ? 176.899 170.115 160.395 1.00 62.57  ? 601 Y86 B C10 1 
HETATM 6979 C C13 . Y86 E 2 .   ? 175.493 172.957 160.961 1.00 62.57  ? 601 Y86 B C13 1 
HETATM 6980 C C15 . Y86 E 2 .   ? 174.313 173.984 162.958 1.00 62.57  ? 601 Y86 B C15 1 
HETATM 6981 C C17 . Y86 E 2 .   ? 171.843 173.850 163.426 1.00 62.57  ? 601 Y86 B C17 1 
HETATM 6982 C C20 . Y86 E 2 .   ? 168.418 176.405 161.436 1.00 62.57  ? 601 Y86 B C20 1 
HETATM 6983 C C21 . Y86 E 2 .   ? 167.081 178.198 162.339 1.00 62.57  ? 601 Y86 B C21 1 
HETATM 6984 C C22 . Y86 E 2 .   ? 166.127 179.284 161.919 1.00 62.57  ? 601 Y86 B C22 1 
HETATM 6985 C C24 . Y86 E 2 .   ? 164.558 179.097 163.893 1.00 62.57  ? 601 Y86 B C24 1 
HETATM 6986 C C26 . Y86 E 2 .   ? 163.126 179.029 165.998 1.00 62.57  ? 601 Y86 B C26 1 
HETATM 6987 C C28 . Y86 E 2 .   ? 163.603 178.288 168.370 1.00 62.57  ? 601 Y86 B C28 1 
HETATM 6988 C C1  . Y86 E 2 .   ? 171.951 170.644 165.084 1.00 62.57  ? 601 Y86 B C1  1 
HETATM 6989 C C11 . Y86 E 2 .   ? 177.499 171.389 160.904 1.00 62.57  ? 601 Y86 B C11 1 
HETATM 6990 C C12 . Y86 E 2 .   ? 176.847 172.622 160.360 1.00 62.57  ? 601 Y86 B C12 1 
HETATM 6991 C C14 . Y86 E 2 .   ? 175.538 173.276 162.433 1.00 62.57  ? 601 Y86 B C14 1 
HETATM 6992 C C16 . Y86 E 2 .   ? 172.999 173.273 162.667 1.00 62.57  ? 601 Y86 B C16 1 
HETATM 6993 C C18 . Y86 E 2 .   ? 171.473 175.250 163.021 1.00 62.57  ? 601 Y86 B C18 1 
HETATM 6994 C C19 . Y86 E 2 .   ? 169.722 176.591 162.181 1.00 62.57  ? 601 Y86 B C19 1 
HETATM 6995 C C2  . Y86 E 2 .   ? 172.812 169.482 165.423 1.00 62.57  ? 601 Y86 B C2  1 
HETATM 6996 C C23 . Y86 E 2 .   ? 165.452 179.997 163.053 1.00 62.57  ? 601 Y86 B C23 1 
HETATM 6997 C C25 . Y86 E 2 .   ? 163.687 179.852 164.866 1.00 62.57  ? 601 Y86 B C25 1 
HETATM 6998 C C27 . Y86 E 2 .   ? 164.157 178.553 166.992 1.00 62.57  ? 601 Y86 B C27 1 
HETATM 6999 C C29 . Y86 E 2 .   ? 164.629 177.840 169.381 1.00 62.57  ? 601 Y86 B C29 1 
HETATM 7000 C C3  . Y86 E 2 .   ? 173.990 169.352 164.507 1.00 62.57  ? 601 Y86 B C3  1 
HETATM 7001 C C30 . Y86 E 2 .   ? 164.147 177.880 170.811 1.00 62.57  ? 601 Y86 B C30 1 
HETATM 7002 C C31 . Y86 E 2 .   ? 162.915 177.055 171.081 1.00 62.57  ? 601 Y86 B C31 1 
HETATM 7003 C C32 . Y86 E 2 .   ? 161.752 177.840 171.633 1.00 62.57  ? 601 Y86 B C32 1 
HETATM 7004 C C33 . Y86 E 2 .   ? 160.509 177.018 171.855 1.00 62.57  ? 601 Y86 B C33 1 
HETATM 7005 C C34 . Y86 E 2 .   ? 159.293 177.811 172.265 1.00 62.57  ? 601 Y86 B C34 1 
HETATM 7006 C C35 . Y86 E 2 .   ? 158.918 178.910 171.303 1.00 62.57  ? 601 Y86 B C35 1 
HETATM 7007 C C36 . Y86 E 2 .   ? 157.435 179.033 171.052 1.00 62.57  ? 601 Y86 B C36 1 
HETATM 7008 C C37 . Y86 E 2 .   ? 156.828 177.817 170.397 1.00 62.57  ? 601 Y86 B C37 1 
HETATM 7009 C C38 . Y86 E 2 .   ? 155.361 177.911 170.072 1.00 62.57  ? 601 Y86 B C38 1 
HETATM 7010 C C39 . Y86 E 2 .   ? 154.812 176.659 169.427 1.00 62.57  ? 601 Y86 B C39 1 
HETATM 7011 C C40 . Y86 E 2 .   ? 168.595 175.798 160.062 1.00 62.57  ? 601 Y86 B C40 1 
HETATM 7012 C C9  . Y86 E 2 .   ? 177.316 168.898 160.701 1.00 62.57  ? 601 Y86 B C9  1 
HETATM 7013 O O1  . Y86 E 2 .   ? 170.266 175.285 162.467 1.00 62.57  ? 601 Y86 B O1  1 
HETATM 7014 O O2  . Y86 E 2 .   ? 167.694 177.657 161.273 1.00 62.57  ? 601 Y86 B O2  1 
HETATM 7015 O O3  . Y86 E 2 .   ? 167.288 177.840 163.469 1.00 62.57  ? 601 Y86 B O3  1 
HETATM 7016 O O4  . Y86 E 2 .   ? 169.020 174.408 160.147 1.00 62.57  ? 601 Y86 B O4  1 
HETATM 7017 O O5  . Y86 E 2 .   ? 167.002 173.356 159.125 1.00 62.57  ? 601 Y86 B O5  1 
HETATM 7018 O O6  . Y86 E 2 .   ? 168.672 171.950 160.398 1.00 62.57  ? 601 Y86 B O6  1 
HETATM 7019 O O7  . Y86 E 2 .   ? 167.178 173.567 161.633 1.00 62.57  ? 601 Y86 B O7  1 
HETATM 7020 O O8  . Y86 E 2 .   ? 172.155 176.227 163.175 1.00 62.57  ? 601 Y86 B O8  1 
HETATM 7021 P P1  . Y86 E 2 .   ? 167.903 173.256 160.340 1.00 62.57  ? 601 Y86 B P1  1 
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