data_8X1T
# 
_entry.id   8X1T 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8X1T         pdb_00008x1t 10.2210/pdb8x1t/pdb 
WWPDB D_1300042446 ?            ?                   
EMDB  EMD-38001    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-05-14 ? 
2 'EM metadata'     1 0 2025-05-14 ? 
3 FSC               1 0 2025-05-14 ? 
4 'Half map'        1 0 2025-05-14 1 
5 'Half map'        1 0 2025-05-14 2 
6 Image             1 0 2025-05-14 ? 
7 Mask              1 0 2025-05-14 1 
8 'Primary map'     1 0 2025-05-14 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 Mask              repository 'Initial release' ? ? 
8 8 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8X1T 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of human DRA (SLC26A3) bound with sulfate' 
_pdbx_database_related.db_id          EMD-38001 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              zyq_lab@fudan.edu.cn 
_pdbx_contact_author.name_first         Yanqing 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-7654-1645 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yang, X.'  1 0000-0001-8393-325X 
'Zhang, Y.' 2 0000-0001-7654-1645 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To be published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cryo-EM structure of human DRA (SLC26A3) bound with sulfate' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yang, X.'  1 0000-0001-8393-325X 
primary 'Zhang, Y.' 2 0000-0001-7654-1645 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Chloride anion exchanger' 85877.844 2 ? ? ? ? 
2 non-polymer syn 'SULFATE ION'              96.063    2 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        DRA 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MDYKDDDDKGTMIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRL
KEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAV
PDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFI
FQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDF
KNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFR
GFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDC
LIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANI
GFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHI
DWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIF
FLTIHDAVLHILMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MDYKDDDDKGTMIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRL
KEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAV
PDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFI
FQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDF
KNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFR
GFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDC
LIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANI
GFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHI
DWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIF
FLTIHDAVLHILMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'SULFATE ION' 
_pdbx_entity_nonpoly.comp_id     SO4 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASP n 
1 3   TYR n 
1 4   LYS n 
1 5   ASP n 
1 6   ASP n 
1 7   ASP n 
1 8   ASP n 
1 9   LYS n 
1 10  GLY n 
1 11  THR n 
1 12  MET n 
1 13  ILE n 
1 14  GLU n 
1 15  PRO n 
1 16  PHE n 
1 17  GLY n 
1 18  ASN n 
1 19  GLN n 
1 20  TYR n 
1 21  ILE n 
1 22  VAL n 
1 23  ALA n 
1 24  ARG n 
1 25  PRO n 
1 26  VAL n 
1 27  TYR n 
1 28  SER n 
1 29  THR n 
1 30  ASN n 
1 31  ALA n 
1 32  PHE n 
1 33  GLU n 
1 34  GLU n 
1 35  ASN n 
1 36  HIS n 
1 37  LYS n 
1 38  LYS n 
1 39  THR n 
1 40  GLY n 
1 41  ARG n 
1 42  HIS n 
1 43  HIS n 
1 44  LYS n 
1 45  THR n 
1 46  PHE n 
1 47  LEU n 
1 48  ASP n 
1 49  HIS n 
1 50  LEU n 
1 51  LYS n 
1 52  VAL n 
1 53  CYS n 
1 54  CYS n 
1 55  SER n 
1 56  CYS n 
1 57  SER n 
1 58  PRO n 
1 59  GLN n 
1 60  LYS n 
1 61  ALA n 
1 62  LYS n 
1 63  ARG n 
1 64  ILE n 
1 65  VAL n 
1 66  LEU n 
1 67  SER n 
1 68  LEU n 
1 69  PHE n 
1 70  PRO n 
1 71  ILE n 
1 72  ALA n 
1 73  SER n 
1 74  TRP n 
1 75  LEU n 
1 76  PRO n 
1 77  ALA n 
1 78  TYR n 
1 79  ARG n 
1 80  LEU n 
1 81  LYS n 
1 82  GLU n 
1 83  TRP n 
1 84  LEU n 
1 85  LEU n 
1 86  SER n 
1 87  ASP n 
1 88  ILE n 
1 89  VAL n 
1 90  SER n 
1 91  GLY n 
1 92  ILE n 
1 93  SER n 
1 94  THR n 
1 95  GLY n 
1 96  ILE n 
1 97  VAL n 
1 98  ALA n 
1 99  VAL n 
1 100 LEU n 
1 101 GLN n 
1 102 GLY n 
1 103 LEU n 
1 104 ALA n 
1 105 PHE n 
1 106 ALA n 
1 107 LEU n 
1 108 LEU n 
1 109 VAL n 
1 110 ASP n 
1 111 ILE n 
1 112 PRO n 
1 113 PRO n 
1 114 VAL n 
1 115 TYR n 
1 116 GLY n 
1 117 LEU n 
1 118 TYR n 
1 119 ALA n 
1 120 SER n 
1 121 PHE n 
1 122 PHE n 
1 123 PRO n 
1 124 ALA n 
1 125 ILE n 
1 126 ILE n 
1 127 TYR n 
1 128 LEU n 
1 129 PHE n 
1 130 PHE n 
1 131 GLY n 
1 132 THR n 
1 133 SER n 
1 134 ARG n 
1 135 HIS n 
1 136 ILE n 
1 137 SER n 
1 138 VAL n 
1 139 GLY n 
1 140 PRO n 
1 141 PHE n 
1 142 PRO n 
1 143 ILE n 
1 144 LEU n 
1 145 SER n 
1 146 MET n 
1 147 MET n 
1 148 VAL n 
1 149 GLY n 
1 150 LEU n 
1 151 ALA n 
1 152 VAL n 
1 153 SER n 
1 154 GLY n 
1 155 ALA n 
1 156 VAL n 
1 157 SER n 
1 158 LYS n 
1 159 ALA n 
1 160 VAL n 
1 161 PRO n 
1 162 ASP n 
1 163 ARG n 
1 164 ASN n 
1 165 ALA n 
1 166 THR n 
1 167 THR n 
1 168 LEU n 
1 169 GLY n 
1 170 LEU n 
1 171 PRO n 
1 172 ASN n 
1 173 ASN n 
1 174 SER n 
1 175 ASN n 
1 176 ASN n 
1 177 SER n 
1 178 SER n 
1 179 LEU n 
1 180 LEU n 
1 181 ASP n 
1 182 ASP n 
1 183 GLU n 
1 184 ARG n 
1 185 VAL n 
1 186 ARG n 
1 187 VAL n 
1 188 ALA n 
1 189 ALA n 
1 190 ALA n 
1 191 ALA n 
1 192 SER n 
1 193 VAL n 
1 194 THR n 
1 195 VAL n 
1 196 LEU n 
1 197 SER n 
1 198 GLY n 
1 199 ILE n 
1 200 ILE n 
1 201 GLN n 
1 202 LEU n 
1 203 ALA n 
1 204 PHE n 
1 205 GLY n 
1 206 ILE n 
1 207 LEU n 
1 208 ARG n 
1 209 ILE n 
1 210 GLY n 
1 211 PHE n 
1 212 VAL n 
1 213 VAL n 
1 214 ILE n 
1 215 TYR n 
1 216 LEU n 
1 217 SER n 
1 218 GLU n 
1 219 SER n 
1 220 LEU n 
1 221 ILE n 
1 222 SER n 
1 223 GLY n 
1 224 PHE n 
1 225 THR n 
1 226 THR n 
1 227 ALA n 
1 228 ALA n 
1 229 ALA n 
1 230 VAL n 
1 231 HIS n 
1 232 VAL n 
1 233 LEU n 
1 234 VAL n 
1 235 SER n 
1 236 GLN n 
1 237 LEU n 
1 238 LYS n 
1 239 PHE n 
1 240 ILE n 
1 241 PHE n 
1 242 GLN n 
1 243 LEU n 
1 244 THR n 
1 245 VAL n 
1 246 PRO n 
1 247 SER n 
1 248 HIS n 
1 249 THR n 
1 250 ASP n 
1 251 PRO n 
1 252 VAL n 
1 253 SER n 
1 254 ILE n 
1 255 PHE n 
1 256 LYS n 
1 257 VAL n 
1 258 LEU n 
1 259 TYR n 
1 260 SER n 
1 261 VAL n 
1 262 PHE n 
1 263 SER n 
1 264 GLN n 
1 265 ILE n 
1 266 GLU n 
1 267 LYS n 
1 268 THR n 
1 269 ASN n 
1 270 ILE n 
1 271 ALA n 
1 272 ASP n 
1 273 LEU n 
1 274 VAL n 
1 275 THR n 
1 276 ALA n 
1 277 LEU n 
1 278 ILE n 
1 279 VAL n 
1 280 LEU n 
1 281 LEU n 
1 282 VAL n 
1 283 VAL n 
1 284 SER n 
1 285 ILE n 
1 286 VAL n 
1 287 LYS n 
1 288 GLU n 
1 289 ILE n 
1 290 ASN n 
1 291 GLN n 
1 292 ARG n 
1 293 PHE n 
1 294 LYS n 
1 295 ASP n 
1 296 LYS n 
1 297 LEU n 
1 298 PRO n 
1 299 VAL n 
1 300 PRO n 
1 301 ILE n 
1 302 PRO n 
1 303 ILE n 
1 304 GLU n 
1 305 PHE n 
1 306 ILE n 
1 307 MET n 
1 308 THR n 
1 309 VAL n 
1 310 ILE n 
1 311 ALA n 
1 312 ALA n 
1 313 GLY n 
1 314 VAL n 
1 315 SER n 
1 316 TYR n 
1 317 GLY n 
1 318 CYS n 
1 319 ASP n 
1 320 PHE n 
1 321 LYS n 
1 322 ASN n 
1 323 ARG n 
1 324 PHE n 
1 325 LYS n 
1 326 VAL n 
1 327 ALA n 
1 328 VAL n 
1 329 VAL n 
1 330 GLY n 
1 331 ASP n 
1 332 MET n 
1 333 ASN n 
1 334 PRO n 
1 335 GLY n 
1 336 PHE n 
1 337 GLN n 
1 338 PRO n 
1 339 PRO n 
1 340 ILE n 
1 341 THR n 
1 342 PRO n 
1 343 ASP n 
1 344 VAL n 
1 345 GLU n 
1 346 THR n 
1 347 PHE n 
1 348 GLN n 
1 349 ASN n 
1 350 THR n 
1 351 VAL n 
1 352 GLY n 
1 353 ASP n 
1 354 CYS n 
1 355 PHE n 
1 356 GLY n 
1 357 ILE n 
1 358 ALA n 
1 359 MET n 
1 360 VAL n 
1 361 ALA n 
1 362 PHE n 
1 363 ALA n 
1 364 VAL n 
1 365 ALA n 
1 366 PHE n 
1 367 SER n 
1 368 VAL n 
1 369 ALA n 
1 370 SER n 
1 371 VAL n 
1 372 TYR n 
1 373 SER n 
1 374 LEU n 
1 375 LYS n 
1 376 TYR n 
1 377 ASP n 
1 378 TYR n 
1 379 PRO n 
1 380 LEU n 
1 381 ASP n 
1 382 GLY n 
1 383 ASN n 
1 384 GLN n 
1 385 GLU n 
1 386 LEU n 
1 387 ILE n 
1 388 ALA n 
1 389 LEU n 
1 390 GLY n 
1 391 LEU n 
1 392 GLY n 
1 393 ASN n 
1 394 ILE n 
1 395 VAL n 
1 396 CYS n 
1 397 GLY n 
1 398 VAL n 
1 399 PHE n 
1 400 ARG n 
1 401 GLY n 
1 402 PHE n 
1 403 ALA n 
1 404 GLY n 
1 405 SER n 
1 406 THR n 
1 407 ALA n 
1 408 LEU n 
1 409 SER n 
1 410 ARG n 
1 411 SER n 
1 412 ALA n 
1 413 VAL n 
1 414 GLN n 
1 415 GLU n 
1 416 SER n 
1 417 THR n 
1 418 GLY n 
1 419 GLY n 
1 420 LYS n 
1 421 THR n 
1 422 GLN n 
1 423 ILE n 
1 424 ALA n 
1 425 GLY n 
1 426 LEU n 
1 427 ILE n 
1 428 GLY n 
1 429 ALA n 
1 430 ILE n 
1 431 ILE n 
1 432 VAL n 
1 433 LEU n 
1 434 ILE n 
1 435 VAL n 
1 436 VAL n 
1 437 LEU n 
1 438 ALA n 
1 439 ILE n 
1 440 GLY n 
1 441 PHE n 
1 442 LEU n 
1 443 LEU n 
1 444 ALA n 
1 445 PRO n 
1 446 LEU n 
1 447 GLN n 
1 448 LYS n 
1 449 SER n 
1 450 VAL n 
1 451 LEU n 
1 452 ALA n 
1 453 ALA n 
1 454 LEU n 
1 455 ALA n 
1 456 LEU n 
1 457 GLY n 
1 458 ASN n 
1 459 LEU n 
1 460 LYS n 
1 461 GLY n 
1 462 MET n 
1 463 LEU n 
1 464 MET n 
1 465 GLN n 
1 466 PHE n 
1 467 ALA n 
1 468 GLU n 
1 469 ILE n 
1 470 GLY n 
1 471 ARG n 
1 472 LEU n 
1 473 TRP n 
1 474 ARG n 
1 475 LYS n 
1 476 ASP n 
1 477 LYS n 
1 478 TYR n 
1 479 ASP n 
1 480 CYS n 
1 481 LEU n 
1 482 ILE n 
1 483 TRP n 
1 484 ILE n 
1 485 MET n 
1 486 THR n 
1 487 PHE n 
1 488 ILE n 
1 489 PHE n 
1 490 THR n 
1 491 ILE n 
1 492 VAL n 
1 493 LEU n 
1 494 GLY n 
1 495 LEU n 
1 496 GLY n 
1 497 LEU n 
1 498 GLY n 
1 499 LEU n 
1 500 ALA n 
1 501 ALA n 
1 502 SER n 
1 503 VAL n 
1 504 ALA n 
1 505 PHE n 
1 506 GLN n 
1 507 LEU n 
1 508 LEU n 
1 509 THR n 
1 510 ILE n 
1 511 VAL n 
1 512 PHE n 
1 513 ARG n 
1 514 THR n 
1 515 GLN n 
1 516 PHE n 
1 517 PRO n 
1 518 LYS n 
1 519 CYS n 
1 520 SER n 
1 521 THR n 
1 522 LEU n 
1 523 ALA n 
1 524 ASN n 
1 525 ILE n 
1 526 GLY n 
1 527 ARG n 
1 528 THR n 
1 529 ASN n 
1 530 ILE n 
1 531 TYR n 
1 532 LYS n 
1 533 ASN n 
1 534 LYS n 
1 535 LYS n 
1 536 ASP n 
1 537 TYR n 
1 538 TYR n 
1 539 ASP n 
1 540 MET n 
1 541 TYR n 
1 542 GLU n 
1 543 PRO n 
1 544 GLU n 
1 545 GLY n 
1 546 VAL n 
1 547 LYS n 
1 548 ILE n 
1 549 PHE n 
1 550 ARG n 
1 551 CYS n 
1 552 PRO n 
1 553 SER n 
1 554 PRO n 
1 555 ILE n 
1 556 TYR n 
1 557 PHE n 
1 558 ALA n 
1 559 ASN n 
1 560 ILE n 
1 561 GLY n 
1 562 PHE n 
1 563 PHE n 
1 564 ARG n 
1 565 ARG n 
1 566 LYS n 
1 567 LEU n 
1 568 ILE n 
1 569 ASP n 
1 570 ALA n 
1 571 VAL n 
1 572 GLY n 
1 573 PHE n 
1 574 SER n 
1 575 PRO n 
1 576 LEU n 
1 577 ARG n 
1 578 ILE n 
1 579 LEU n 
1 580 ARG n 
1 581 LYS n 
1 582 ARG n 
1 583 ASN n 
1 584 LYS n 
1 585 ALA n 
1 586 LEU n 
1 587 ARG n 
1 588 LYS n 
1 589 ILE n 
1 590 ARG n 
1 591 LYS n 
1 592 LEU n 
1 593 GLN n 
1 594 LYS n 
1 595 GLN n 
1 596 GLY n 
1 597 LEU n 
1 598 LEU n 
1 599 GLN n 
1 600 VAL n 
1 601 THR n 
1 602 PRO n 
1 603 LYS n 
1 604 GLY n 
1 605 PHE n 
1 606 ILE n 
1 607 CYS n 
1 608 THR n 
1 609 VAL n 
1 610 ASP n 
1 611 THR n 
1 612 ILE n 
1 613 LYS n 
1 614 ASP n 
1 615 SER n 
1 616 ASP n 
1 617 GLU n 
1 618 GLU n 
1 619 LEU n 
1 620 ASP n 
1 621 ASN n 
1 622 ASN n 
1 623 GLN n 
1 624 ILE n 
1 625 GLU n 
1 626 VAL n 
1 627 LEU n 
1 628 ASP n 
1 629 GLN n 
1 630 PRO n 
1 631 ILE n 
1 632 ASN n 
1 633 THR n 
1 634 THR n 
1 635 ASP n 
1 636 LEU n 
1 637 PRO n 
1 638 PHE n 
1 639 HIS n 
1 640 ILE n 
1 641 ASP n 
1 642 TRP n 
1 643 ASN n 
1 644 ASP n 
1 645 ASP n 
1 646 LEU n 
1 647 PRO n 
1 648 LEU n 
1 649 ASN n 
1 650 ILE n 
1 651 GLU n 
1 652 VAL n 
1 653 PRO n 
1 654 LYS n 
1 655 ILE n 
1 656 SER n 
1 657 LEU n 
1 658 HIS n 
1 659 SER n 
1 660 LEU n 
1 661 ILE n 
1 662 LEU n 
1 663 ASP n 
1 664 PHE n 
1 665 SER n 
1 666 ALA n 
1 667 VAL n 
1 668 SER n 
1 669 PHE n 
1 670 LEU n 
1 671 ASP n 
1 672 VAL n 
1 673 SER n 
1 674 SER n 
1 675 VAL n 
1 676 ARG n 
1 677 GLY n 
1 678 LEU n 
1 679 LYS n 
1 680 SER n 
1 681 ILE n 
1 682 LEU n 
1 683 GLN n 
1 684 GLU n 
1 685 PHE n 
1 686 ILE n 
1 687 ARG n 
1 688 ILE n 
1 689 LYS n 
1 690 VAL n 
1 691 ASP n 
1 692 VAL n 
1 693 TYR n 
1 694 ILE n 
1 695 VAL n 
1 696 GLY n 
1 697 THR n 
1 698 ASP n 
1 699 ASP n 
1 700 ASP n 
1 701 PHE n 
1 702 ILE n 
1 703 GLU n 
1 704 LYS n 
1 705 LEU n 
1 706 ASN n 
1 707 ARG n 
1 708 TYR n 
1 709 GLU n 
1 710 PHE n 
1 711 PHE n 
1 712 ASP n 
1 713 GLY n 
1 714 GLU n 
1 715 VAL n 
1 716 LYS n 
1 717 SER n 
1 718 SER n 
1 719 ILE n 
1 720 PHE n 
1 721 PHE n 
1 722 LEU n 
1 723 THR n 
1 724 ILE n 
1 725 HIS n 
1 726 ASP n 
1 727 ALA n 
1 728 VAL n 
1 729 LEU n 
1 730 HIS n 
1 731 ILE n 
1 732 LEU n 
1 733 MET n 
1 734 LYS n 
1 735 LYS n 
1 736 ASP n 
1 737 TYR n 
1 738 SER n 
1 739 THR n 
1 740 SER n 
1 741 LYS n 
1 742 PHE n 
1 743 ASN n 
1 744 PRO n 
1 745 SER n 
1 746 GLN n 
1 747 GLU n 
1 748 LYS n 
1 749 ASP n 
1 750 GLY n 
1 751 LYS n 
1 752 ILE n 
1 753 ASP n 
1 754 PHE n 
1 755 THR n 
1 756 ILE n 
1 757 ASN n 
1 758 THR n 
1 759 ASN n 
1 760 GLY n 
1 761 GLY n 
1 762 LEU n 
1 763 ARG n 
1 764 ASN n 
1 765 ARG n 
1 766 VAL n 
1 767 TYR n 
1 768 GLU n 
1 769 VAL n 
1 770 PRO n 
1 771 VAL n 
1 772 GLU n 
1 773 THR n 
1 774 LYS n 
1 775 PHE n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   775 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 SLC26A3 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            HEK293 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'   ? 'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -10 ?   ?   ?   A . n 
A 1 2   ASP 2   -9  ?   ?   ?   A . n 
A 1 3   TYR 3   -8  ?   ?   ?   A . n 
A 1 4   LYS 4   -7  ?   ?   ?   A . n 
A 1 5   ASP 5   -6  ?   ?   ?   A . n 
A 1 6   ASP 6   -5  ?   ?   ?   A . n 
A 1 7   ASP 7   -4  ?   ?   ?   A . n 
A 1 8   ASP 8   -3  ?   ?   ?   A . n 
A 1 9   LYS 9   -2  ?   ?   ?   A . n 
A 1 10  GLY 10  -1  ?   ?   ?   A . n 
A 1 11  THR 11  0   ?   ?   ?   A . n 
A 1 12  MET 12  1   ?   ?   ?   A . n 
A 1 13  ILE 13  2   ?   ?   ?   A . n 
A 1 14  GLU 14  3   ?   ?   ?   A . n 
A 1 15  PRO 15  4   ?   ?   ?   A . n 
A 1 16  PHE 16  5   ?   ?   ?   A . n 
A 1 17  GLY 17  6   ?   ?   ?   A . n 
A 1 18  ASN 18  7   7   ASN ASN A . n 
A 1 19  GLN 19  8   8   GLN GLN A . n 
A 1 20  TYR 20  9   9   TYR TYR A . n 
A 1 21  ILE 21  10  10  ILE ILE A . n 
A 1 22  VAL 22  11  11  VAL VAL A . n 
A 1 23  ALA 23  12  12  ALA ALA A . n 
A 1 24  ARG 24  13  13  ARG ARG A . n 
A 1 25  PRO 25  14  14  PRO PRO A . n 
A 1 26  VAL 26  15  15  VAL VAL A . n 
A 1 27  TYR 27  16  16  TYR TYR A . n 
A 1 28  SER 28  17  17  SER SER A . n 
A 1 29  THR 29  18  18  THR THR A . n 
A 1 30  ASN 30  19  19  ASN ASN A . n 
A 1 31  ALA 31  20  20  ALA ALA A . n 
A 1 32  PHE 32  21  21  PHE PHE A . n 
A 1 33  GLU 33  22  22  GLU GLU A . n 
A 1 34  GLU 34  23  23  GLU GLU A . n 
A 1 35  ASN 35  24  24  ASN ASN A . n 
A 1 36  HIS 36  25  25  HIS HIS A . n 
A 1 37  LYS 37  26  26  LYS LYS A . n 
A 1 38  LYS 38  27  27  LYS LYS A . n 
A 1 39  THR 39  28  28  THR THR A . n 
A 1 40  GLY 40  29  29  GLY GLY A . n 
A 1 41  ARG 41  30  30  ARG ARG A . n 
A 1 42  HIS 42  31  31  HIS HIS A . n 
A 1 43  HIS 43  32  32  HIS HIS A . n 
A 1 44  LYS 44  33  33  LYS LYS A . n 
A 1 45  THR 45  34  34  THR THR A . n 
A 1 46  PHE 46  35  35  PHE PHE A . n 
A 1 47  LEU 47  36  36  LEU LEU A . n 
A 1 48  ASP 48  37  37  ASP ASP A . n 
A 1 49  HIS 49  38  38  HIS HIS A . n 
A 1 50  LEU 50  39  39  LEU LEU A . n 
A 1 51  LYS 51  40  40  LYS LYS A . n 
A 1 52  VAL 52  41  41  VAL VAL A . n 
A 1 53  CYS 53  42  42  CYS CYS A . n 
A 1 54  CYS 54  43  43  CYS CYS A . n 
A 1 55  SER 55  44  44  SER SER A . n 
A 1 56  CYS 56  45  45  CYS CYS A . n 
A 1 57  SER 57  46  46  SER SER A . n 
A 1 58  PRO 58  47  47  PRO PRO A . n 
A 1 59  GLN 59  48  48  GLN GLN A . n 
A 1 60  LYS 60  49  49  LYS LYS A . n 
A 1 61  ALA 61  50  50  ALA ALA A . n 
A 1 62  LYS 62  51  51  LYS LYS A . n 
A 1 63  ARG 63  52  52  ARG ARG A . n 
A 1 64  ILE 64  53  53  ILE ILE A . n 
A 1 65  VAL 65  54  54  VAL VAL A . n 
A 1 66  LEU 66  55  55  LEU LEU A . n 
A 1 67  SER 67  56  56  SER SER A . n 
A 1 68  LEU 68  57  57  LEU LEU A . n 
A 1 69  PHE 69  58  58  PHE PHE A . n 
A 1 70  PRO 70  59  59  PRO PRO A . n 
A 1 71  ILE 71  60  60  ILE ILE A . n 
A 1 72  ALA 72  61  61  ALA ALA A . n 
A 1 73  SER 73  62  62  SER SER A . n 
A 1 74  TRP 74  63  63  TRP TRP A . n 
A 1 75  LEU 75  64  64  LEU LEU A . n 
A 1 76  PRO 76  65  65  PRO PRO A . n 
A 1 77  ALA 77  66  66  ALA ALA A . n 
A 1 78  TYR 78  67  67  TYR TYR A . n 
A 1 79  ARG 79  68  68  ARG ARG A . n 
A 1 80  LEU 80  69  69  LEU LEU A . n 
A 1 81  LYS 81  70  70  LYS LYS A . n 
A 1 82  GLU 82  71  71  GLU GLU A . n 
A 1 83  TRP 83  72  72  TRP TRP A . n 
A 1 84  LEU 84  73  73  LEU LEU A . n 
A 1 85  LEU 85  74  74  LEU LEU A . n 
A 1 86  SER 86  75  75  SER SER A . n 
A 1 87  ASP 87  76  76  ASP ASP A . n 
A 1 88  ILE 88  77  77  ILE ILE A . n 
A 1 89  VAL 89  78  78  VAL VAL A . n 
A 1 90  SER 90  79  79  SER SER A . n 
A 1 91  GLY 91  80  80  GLY GLY A . n 
A 1 92  ILE 92  81  81  ILE ILE A . n 
A 1 93  SER 93  82  82  SER SER A . n 
A 1 94  THR 94  83  83  THR THR A . n 
A 1 95  GLY 95  84  84  GLY GLY A . n 
A 1 96  ILE 96  85  85  ILE ILE A . n 
A 1 97  VAL 97  86  86  VAL VAL A . n 
A 1 98  ALA 98  87  87  ALA ALA A . n 
A 1 99  VAL 99  88  88  VAL VAL A . n 
A 1 100 LEU 100 89  89  LEU LEU A . n 
A 1 101 GLN 101 90  90  GLN GLN A . n 
A 1 102 GLY 102 91  91  GLY GLY A . n 
A 1 103 LEU 103 92  92  LEU LEU A . n 
A 1 104 ALA 104 93  93  ALA ALA A . n 
A 1 105 PHE 105 94  94  PHE PHE A . n 
A 1 106 ALA 106 95  95  ALA ALA A . n 
A 1 107 LEU 107 96  96  LEU LEU A . n 
A 1 108 LEU 108 97  97  LEU LEU A . n 
A 1 109 VAL 109 98  98  VAL VAL A . n 
A 1 110 ASP 110 99  99  ASP ASP A . n 
A 1 111 ILE 111 100 100 ILE ILE A . n 
A 1 112 PRO 112 101 101 PRO PRO A . n 
A 1 113 PRO 113 102 102 PRO PRO A . n 
A 1 114 VAL 114 103 103 VAL VAL A . n 
A 1 115 TYR 115 104 104 TYR TYR A . n 
A 1 116 GLY 116 105 105 GLY GLY A . n 
A 1 117 LEU 117 106 106 LEU LEU A . n 
A 1 118 TYR 118 107 107 TYR TYR A . n 
A 1 119 ALA 119 108 108 ALA ALA A . n 
A 1 120 SER 120 109 109 SER SER A . n 
A 1 121 PHE 121 110 110 PHE PHE A . n 
A 1 122 PHE 122 111 111 PHE PHE A . n 
A 1 123 PRO 123 112 112 PRO PRO A . n 
A 1 124 ALA 124 113 113 ALA ALA A . n 
A 1 125 ILE 125 114 114 ILE ILE A . n 
A 1 126 ILE 126 115 115 ILE ILE A . n 
A 1 127 TYR 127 116 116 TYR TYR A . n 
A 1 128 LEU 128 117 117 LEU LEU A . n 
A 1 129 PHE 129 118 118 PHE PHE A . n 
A 1 130 PHE 130 119 119 PHE PHE A . n 
A 1 131 GLY 131 120 120 GLY GLY A . n 
A 1 132 THR 132 121 121 THR THR A . n 
A 1 133 SER 133 122 122 SER SER A . n 
A 1 134 ARG 134 123 123 ARG ARG A . n 
A 1 135 HIS 135 124 124 HIS HIS A . n 
A 1 136 ILE 136 125 125 ILE ILE A . n 
A 1 137 SER 137 126 126 SER SER A . n 
A 1 138 VAL 138 127 127 VAL VAL A . n 
A 1 139 GLY 139 128 128 GLY GLY A . n 
A 1 140 PRO 140 129 129 PRO PRO A . n 
A 1 141 PHE 141 130 130 PHE PHE A . n 
A 1 142 PRO 142 131 131 PRO PRO A . n 
A 1 143 ILE 143 132 132 ILE ILE A . n 
A 1 144 LEU 144 133 133 LEU LEU A . n 
A 1 145 SER 145 134 134 SER SER A . n 
A 1 146 MET 146 135 135 MET MET A . n 
A 1 147 MET 147 136 136 MET MET A . n 
A 1 148 VAL 148 137 137 VAL VAL A . n 
A 1 149 GLY 149 138 138 GLY GLY A . n 
A 1 150 LEU 150 139 139 LEU LEU A . n 
A 1 151 ALA 151 140 140 ALA ALA A . n 
A 1 152 VAL 152 141 141 VAL VAL A . n 
A 1 153 SER 153 142 142 SER SER A . n 
A 1 154 GLY 154 143 143 GLY GLY A . n 
A 1 155 ALA 155 144 144 ALA ALA A . n 
A 1 156 VAL 156 145 145 VAL VAL A . n 
A 1 157 SER 157 146 146 SER SER A . n 
A 1 158 LYS 158 147 147 LYS LYS A . n 
A 1 159 ALA 159 148 148 ALA ALA A . n 
A 1 160 VAL 160 149 149 VAL VAL A . n 
A 1 161 PRO 161 150 150 PRO PRO A . n 
A 1 162 ASP 162 151 ?   ?   ?   A . n 
A 1 163 ARG 163 152 ?   ?   ?   A . n 
A 1 164 ASN 164 153 ?   ?   ?   A . n 
A 1 165 ALA 165 154 ?   ?   ?   A . n 
A 1 166 THR 166 155 ?   ?   ?   A . n 
A 1 167 THR 167 156 ?   ?   ?   A . n 
A 1 168 LEU 168 157 ?   ?   ?   A . n 
A 1 169 GLY 169 158 ?   ?   ?   A . n 
A 1 170 LEU 170 159 ?   ?   ?   A . n 
A 1 171 PRO 171 160 ?   ?   ?   A . n 
A 1 172 ASN 172 161 ?   ?   ?   A . n 
A 1 173 ASN 173 162 ?   ?   ?   A . n 
A 1 174 SER 174 163 ?   ?   ?   A . n 
A 1 175 ASN 175 164 ?   ?   ?   A . n 
A 1 176 ASN 176 165 ?   ?   ?   A . n 
A 1 177 SER 177 166 ?   ?   ?   A . n 
A 1 178 SER 178 167 ?   ?   ?   A . n 
A 1 179 LEU 179 168 168 LEU LEU A . n 
A 1 180 LEU 180 169 169 LEU LEU A . n 
A 1 181 ASP 181 170 170 ASP ASP A . n 
A 1 182 ASP 182 171 171 ASP ASP A . n 
A 1 183 GLU 183 172 172 GLU GLU A . n 
A 1 184 ARG 184 173 173 ARG ARG A . n 
A 1 185 VAL 185 174 174 VAL VAL A . n 
A 1 186 ARG 186 175 175 ARG ARG A . n 
A 1 187 VAL 187 176 176 VAL VAL A . n 
A 1 188 ALA 188 177 177 ALA ALA A . n 
A 1 189 ALA 189 178 178 ALA ALA A . n 
A 1 190 ALA 190 179 179 ALA ALA A . n 
A 1 191 ALA 191 180 180 ALA ALA A . n 
A 1 192 SER 192 181 181 SER SER A . n 
A 1 193 VAL 193 182 182 VAL VAL A . n 
A 1 194 THR 194 183 183 THR THR A . n 
A 1 195 VAL 195 184 184 VAL VAL A . n 
A 1 196 LEU 196 185 185 LEU LEU A . n 
A 1 197 SER 197 186 186 SER SER A . n 
A 1 198 GLY 198 187 187 GLY GLY A . n 
A 1 199 ILE 199 188 188 ILE ILE A . n 
A 1 200 ILE 200 189 189 ILE ILE A . n 
A 1 201 GLN 201 190 190 GLN GLN A . n 
A 1 202 LEU 202 191 191 LEU LEU A . n 
A 1 203 ALA 203 192 192 ALA ALA A . n 
A 1 204 PHE 204 193 193 PHE PHE A . n 
A 1 205 GLY 205 194 194 GLY GLY A . n 
A 1 206 ILE 206 195 195 ILE ILE A . n 
A 1 207 LEU 207 196 196 LEU LEU A . n 
A 1 208 ARG 208 197 197 ARG ARG A . n 
A 1 209 ILE 209 198 198 ILE ILE A . n 
A 1 210 GLY 210 199 199 GLY GLY A . n 
A 1 211 PHE 211 200 200 PHE PHE A . n 
A 1 212 VAL 212 201 201 VAL VAL A . n 
A 1 213 VAL 213 202 202 VAL VAL A . n 
A 1 214 ILE 214 203 203 ILE ILE A . n 
A 1 215 TYR 215 204 204 TYR TYR A . n 
A 1 216 LEU 216 205 205 LEU LEU A . n 
A 1 217 SER 217 206 206 SER SER A . n 
A 1 218 GLU 218 207 207 GLU GLU A . n 
A 1 219 SER 219 208 208 SER SER A . n 
A 1 220 LEU 220 209 209 LEU LEU A . n 
A 1 221 ILE 221 210 210 ILE ILE A . n 
A 1 222 SER 222 211 211 SER SER A . n 
A 1 223 GLY 223 212 212 GLY GLY A . n 
A 1 224 PHE 224 213 213 PHE PHE A . n 
A 1 225 THR 225 214 214 THR THR A . n 
A 1 226 THR 226 215 215 THR THR A . n 
A 1 227 ALA 227 216 216 ALA ALA A . n 
A 1 228 ALA 228 217 217 ALA ALA A . n 
A 1 229 ALA 229 218 218 ALA ALA A . n 
A 1 230 VAL 230 219 219 VAL VAL A . n 
A 1 231 HIS 231 220 220 HIS HIS A . n 
A 1 232 VAL 232 221 221 VAL VAL A . n 
A 1 233 LEU 233 222 222 LEU LEU A . n 
A 1 234 VAL 234 223 223 VAL VAL A . n 
A 1 235 SER 235 224 224 SER SER A . n 
A 1 236 GLN 236 225 225 GLN GLN A . n 
A 1 237 LEU 237 226 226 LEU LEU A . n 
A 1 238 LYS 238 227 227 LYS LYS A . n 
A 1 239 PHE 239 228 228 PHE PHE A . n 
A 1 240 ILE 240 229 229 ILE ILE A . n 
A 1 241 PHE 241 230 230 PHE PHE A . n 
A 1 242 GLN 242 231 231 GLN GLN A . n 
A 1 243 LEU 243 232 232 LEU LEU A . n 
A 1 244 THR 244 233 233 THR THR A . n 
A 1 245 VAL 245 234 234 VAL VAL A . n 
A 1 246 PRO 246 235 235 PRO PRO A . n 
A 1 247 SER 247 236 236 SER SER A . n 
A 1 248 HIS 248 237 237 HIS HIS A . n 
A 1 249 THR 249 238 238 THR THR A . n 
A 1 250 ASP 250 239 239 ASP ASP A . n 
A 1 251 PRO 251 240 240 PRO PRO A . n 
A 1 252 VAL 252 241 241 VAL VAL A . n 
A 1 253 SER 253 242 242 SER SER A . n 
A 1 254 ILE 254 243 243 ILE ILE A . n 
A 1 255 PHE 255 244 244 PHE PHE A . n 
A 1 256 LYS 256 245 245 LYS LYS A . n 
A 1 257 VAL 257 246 246 VAL VAL A . n 
A 1 258 LEU 258 247 247 LEU LEU A . n 
A 1 259 TYR 259 248 248 TYR TYR A . n 
A 1 260 SER 260 249 249 SER SER A . n 
A 1 261 VAL 261 250 250 VAL VAL A . n 
A 1 262 PHE 262 251 251 PHE PHE A . n 
A 1 263 SER 263 252 252 SER SER A . n 
A 1 264 GLN 264 253 253 GLN GLN A . n 
A 1 265 ILE 265 254 254 ILE ILE A . n 
A 1 266 GLU 266 255 255 GLU GLU A . n 
A 1 267 LYS 267 256 256 LYS LYS A . n 
A 1 268 THR 268 257 257 THR THR A . n 
A 1 269 ASN 269 258 258 ASN ASN A . n 
A 1 270 ILE 270 259 259 ILE ILE A . n 
A 1 271 ALA 271 260 260 ALA ALA A . n 
A 1 272 ASP 272 261 261 ASP ASP A . n 
A 1 273 LEU 273 262 262 LEU LEU A . n 
A 1 274 VAL 274 263 263 VAL VAL A . n 
A 1 275 THR 275 264 264 THR THR A . n 
A 1 276 ALA 276 265 265 ALA ALA A . n 
A 1 277 LEU 277 266 266 LEU LEU A . n 
A 1 278 ILE 278 267 267 ILE ILE A . n 
A 1 279 VAL 279 268 268 VAL VAL A . n 
A 1 280 LEU 280 269 269 LEU LEU A . n 
A 1 281 LEU 281 270 270 LEU LEU A . n 
A 1 282 VAL 282 271 271 VAL VAL A . n 
A 1 283 VAL 283 272 272 VAL VAL A . n 
A 1 284 SER 284 273 273 SER SER A . n 
A 1 285 ILE 285 274 274 ILE ILE A . n 
A 1 286 VAL 286 275 275 VAL VAL A . n 
A 1 287 LYS 287 276 276 LYS LYS A . n 
A 1 288 GLU 288 277 277 GLU GLU A . n 
A 1 289 ILE 289 278 278 ILE ILE A . n 
A 1 290 ASN 290 279 279 ASN ASN A . n 
A 1 291 GLN 291 280 280 GLN GLN A . n 
A 1 292 ARG 292 281 281 ARG ARG A . n 
A 1 293 PHE 293 282 282 PHE PHE A . n 
A 1 294 LYS 294 283 283 LYS LYS A . n 
A 1 295 ASP 295 284 284 ASP ASP A . n 
A 1 296 LYS 296 285 285 LYS LYS A . n 
A 1 297 LEU 297 286 286 LEU LEU A . n 
A 1 298 PRO 298 287 287 PRO PRO A . n 
A 1 299 VAL 299 288 288 VAL VAL A . n 
A 1 300 PRO 300 289 289 PRO PRO A . n 
A 1 301 ILE 301 290 290 ILE ILE A . n 
A 1 302 PRO 302 291 291 PRO PRO A . n 
A 1 303 ILE 303 292 292 ILE ILE A . n 
A 1 304 GLU 304 293 293 GLU GLU A . n 
A 1 305 PHE 305 294 294 PHE PHE A . n 
A 1 306 ILE 306 295 295 ILE ILE A . n 
A 1 307 MET 307 296 296 MET MET A . n 
A 1 308 THR 308 297 297 THR THR A . n 
A 1 309 VAL 309 298 298 VAL VAL A . n 
A 1 310 ILE 310 299 299 ILE ILE A . n 
A 1 311 ALA 311 300 300 ALA ALA A . n 
A 1 312 ALA 312 301 301 ALA ALA A . n 
A 1 313 GLY 313 302 302 GLY GLY A . n 
A 1 314 VAL 314 303 303 VAL VAL A . n 
A 1 315 SER 315 304 304 SER SER A . n 
A 1 316 TYR 316 305 305 TYR TYR A . n 
A 1 317 GLY 317 306 306 GLY GLY A . n 
A 1 318 CYS 318 307 307 CYS CYS A . n 
A 1 319 ASP 319 308 308 ASP ASP A . n 
A 1 320 PHE 320 309 309 PHE PHE A . n 
A 1 321 LYS 321 310 310 LYS LYS A . n 
A 1 322 ASN 322 311 311 ASN ASN A . n 
A 1 323 ARG 323 312 312 ARG ARG A . n 
A 1 324 PHE 324 313 313 PHE PHE A . n 
A 1 325 LYS 325 314 314 LYS LYS A . n 
A 1 326 VAL 326 315 315 VAL VAL A . n 
A 1 327 ALA 327 316 316 ALA ALA A . n 
A 1 328 VAL 328 317 317 VAL VAL A . n 
A 1 329 VAL 329 318 318 VAL VAL A . n 
A 1 330 GLY 330 319 319 GLY GLY A . n 
A 1 331 ASP 331 320 320 ASP ASP A . n 
A 1 332 MET 332 321 321 MET MET A . n 
A 1 333 ASN 333 322 322 ASN ASN A . n 
A 1 334 PRO 334 323 323 PRO PRO A . n 
A 1 335 GLY 335 324 324 GLY GLY A . n 
A 1 336 PHE 336 325 325 PHE PHE A . n 
A 1 337 GLN 337 326 326 GLN GLN A . n 
A 1 338 PRO 338 327 327 PRO PRO A . n 
A 1 339 PRO 339 328 328 PRO PRO A . n 
A 1 340 ILE 340 329 329 ILE ILE A . n 
A 1 341 THR 341 330 330 THR THR A . n 
A 1 342 PRO 342 331 331 PRO PRO A . n 
A 1 343 ASP 343 332 332 ASP ASP A . n 
A 1 344 VAL 344 333 333 VAL VAL A . n 
A 1 345 GLU 345 334 334 GLU GLU A . n 
A 1 346 THR 346 335 335 THR THR A . n 
A 1 347 PHE 347 336 336 PHE PHE A . n 
A 1 348 GLN 348 337 337 GLN GLN A . n 
A 1 349 ASN 349 338 338 ASN ASN A . n 
A 1 350 THR 350 339 339 THR THR A . n 
A 1 351 VAL 351 340 340 VAL VAL A . n 
A 1 352 GLY 352 341 341 GLY GLY A . n 
A 1 353 ASP 353 342 342 ASP ASP A . n 
A 1 354 CYS 354 343 343 CYS CYS A . n 
A 1 355 PHE 355 344 344 PHE PHE A . n 
A 1 356 GLY 356 345 345 GLY GLY A . n 
A 1 357 ILE 357 346 346 ILE ILE A . n 
A 1 358 ALA 358 347 347 ALA ALA A . n 
A 1 359 MET 359 348 348 MET MET A . n 
A 1 360 VAL 360 349 349 VAL VAL A . n 
A 1 361 ALA 361 350 350 ALA ALA A . n 
A 1 362 PHE 362 351 351 PHE PHE A . n 
A 1 363 ALA 363 352 352 ALA ALA A . n 
A 1 364 VAL 364 353 353 VAL VAL A . n 
A 1 365 ALA 365 354 354 ALA ALA A . n 
A 1 366 PHE 366 355 355 PHE PHE A . n 
A 1 367 SER 367 356 356 SER SER A . n 
A 1 368 VAL 368 357 357 VAL VAL A . n 
A 1 369 ALA 369 358 358 ALA ALA A . n 
A 1 370 SER 370 359 359 SER SER A . n 
A 1 371 VAL 371 360 360 VAL VAL A . n 
A 1 372 TYR 372 361 361 TYR TYR A . n 
A 1 373 SER 373 362 362 SER SER A . n 
A 1 374 LEU 374 363 363 LEU LEU A . n 
A 1 375 LYS 375 364 364 LYS LYS A . n 
A 1 376 TYR 376 365 365 TYR TYR A . n 
A 1 377 ASP 377 366 366 ASP ASP A . n 
A 1 378 TYR 378 367 367 TYR TYR A . n 
A 1 379 PRO 379 368 368 PRO PRO A . n 
A 1 380 LEU 380 369 369 LEU LEU A . n 
A 1 381 ASP 381 370 370 ASP ASP A . n 
A 1 382 GLY 382 371 371 GLY GLY A . n 
A 1 383 ASN 383 372 372 ASN ASN A . n 
A 1 384 GLN 384 373 373 GLN GLN A . n 
A 1 385 GLU 385 374 374 GLU GLU A . n 
A 1 386 LEU 386 375 375 LEU LEU A . n 
A 1 387 ILE 387 376 376 ILE ILE A . n 
A 1 388 ALA 388 377 377 ALA ALA A . n 
A 1 389 LEU 389 378 378 LEU LEU A . n 
A 1 390 GLY 390 379 379 GLY GLY A . n 
A 1 391 LEU 391 380 380 LEU LEU A . n 
A 1 392 GLY 392 381 381 GLY GLY A . n 
A 1 393 ASN 393 382 382 ASN ASN A . n 
A 1 394 ILE 394 383 383 ILE ILE A . n 
A 1 395 VAL 395 384 384 VAL VAL A . n 
A 1 396 CYS 396 385 385 CYS CYS A . n 
A 1 397 GLY 397 386 386 GLY GLY A . n 
A 1 398 VAL 398 387 387 VAL VAL A . n 
A 1 399 PHE 399 388 388 PHE PHE A . n 
A 1 400 ARG 400 389 389 ARG ARG A . n 
A 1 401 GLY 401 390 390 GLY GLY A . n 
A 1 402 PHE 402 391 391 PHE PHE A . n 
A 1 403 ALA 403 392 392 ALA ALA A . n 
A 1 404 GLY 404 393 393 GLY GLY A . n 
A 1 405 SER 405 394 394 SER SER A . n 
A 1 406 THR 406 395 395 THR THR A . n 
A 1 407 ALA 407 396 396 ALA ALA A . n 
A 1 408 LEU 408 397 397 LEU LEU A . n 
A 1 409 SER 409 398 398 SER SER A . n 
A 1 410 ARG 410 399 399 ARG ARG A . n 
A 1 411 SER 411 400 400 SER SER A . n 
A 1 412 ALA 412 401 401 ALA ALA A . n 
A 1 413 VAL 413 402 402 VAL VAL A . n 
A 1 414 GLN 414 403 403 GLN GLN A . n 
A 1 415 GLU 415 404 404 GLU GLU A . n 
A 1 416 SER 416 405 405 SER SER A . n 
A 1 417 THR 417 406 406 THR THR A . n 
A 1 418 GLY 418 407 407 GLY GLY A . n 
A 1 419 GLY 419 408 408 GLY GLY A . n 
A 1 420 LYS 420 409 409 LYS LYS A . n 
A 1 421 THR 421 410 410 THR THR A . n 
A 1 422 GLN 422 411 411 GLN GLN A . n 
A 1 423 ILE 423 412 412 ILE ILE A . n 
A 1 424 ALA 424 413 413 ALA ALA A . n 
A 1 425 GLY 425 414 414 GLY GLY A . n 
A 1 426 LEU 426 415 415 LEU LEU A . n 
A 1 427 ILE 427 416 416 ILE ILE A . n 
A 1 428 GLY 428 417 417 GLY GLY A . n 
A 1 429 ALA 429 418 418 ALA ALA A . n 
A 1 430 ILE 430 419 419 ILE ILE A . n 
A 1 431 ILE 431 420 420 ILE ILE A . n 
A 1 432 VAL 432 421 421 VAL VAL A . n 
A 1 433 LEU 433 422 422 LEU LEU A . n 
A 1 434 ILE 434 423 423 ILE ILE A . n 
A 1 435 VAL 435 424 424 VAL VAL A . n 
A 1 436 VAL 436 425 425 VAL VAL A . n 
A 1 437 LEU 437 426 426 LEU LEU A . n 
A 1 438 ALA 438 427 427 ALA ALA A . n 
A 1 439 ILE 439 428 428 ILE ILE A . n 
A 1 440 GLY 440 429 429 GLY GLY A . n 
A 1 441 PHE 441 430 430 PHE PHE A . n 
A 1 442 LEU 442 431 431 LEU LEU A . n 
A 1 443 LEU 443 432 432 LEU LEU A . n 
A 1 444 ALA 444 433 433 ALA ALA A . n 
A 1 445 PRO 445 434 434 PRO PRO A . n 
A 1 446 LEU 446 435 435 LEU LEU A . n 
A 1 447 GLN 447 436 436 GLN GLN A . n 
A 1 448 LYS 448 437 437 LYS LYS A . n 
A 1 449 SER 449 438 438 SER SER A . n 
A 1 450 VAL 450 439 439 VAL VAL A . n 
A 1 451 LEU 451 440 440 LEU LEU A . n 
A 1 452 ALA 452 441 441 ALA ALA A . n 
A 1 453 ALA 453 442 442 ALA ALA A . n 
A 1 454 LEU 454 443 443 LEU LEU A . n 
A 1 455 ALA 455 444 444 ALA ALA A . n 
A 1 456 LEU 456 445 445 LEU LEU A . n 
A 1 457 GLY 457 446 446 GLY GLY A . n 
A 1 458 ASN 458 447 447 ASN ASN A . n 
A 1 459 LEU 459 448 448 LEU LEU A . n 
A 1 460 LYS 460 449 449 LYS LYS A . n 
A 1 461 GLY 461 450 450 GLY GLY A . n 
A 1 462 MET 462 451 451 MET MET A . n 
A 1 463 LEU 463 452 452 LEU LEU A . n 
A 1 464 MET 464 453 453 MET MET A . n 
A 1 465 GLN 465 454 454 GLN GLN A . n 
A 1 466 PHE 466 455 455 PHE PHE A . n 
A 1 467 ALA 467 456 456 ALA ALA A . n 
A 1 468 GLU 468 457 457 GLU GLU A . n 
A 1 469 ILE 469 458 458 ILE ILE A . n 
A 1 470 GLY 470 459 459 GLY GLY A . n 
A 1 471 ARG 471 460 460 ARG ARG A . n 
A 1 472 LEU 472 461 461 LEU LEU A . n 
A 1 473 TRP 473 462 462 TRP TRP A . n 
A 1 474 ARG 474 463 463 ARG ARG A . n 
A 1 475 LYS 475 464 464 LYS LYS A . n 
A 1 476 ASP 476 465 465 ASP ASP A . n 
A 1 477 LYS 477 466 466 LYS LYS A . n 
A 1 478 TYR 478 467 467 TYR TYR A . n 
A 1 479 ASP 479 468 468 ASP ASP A . n 
A 1 480 CYS 480 469 469 CYS CYS A . n 
A 1 481 LEU 481 470 470 LEU LEU A . n 
A 1 482 ILE 482 471 471 ILE ILE A . n 
A 1 483 TRP 483 472 472 TRP TRP A . n 
A 1 484 ILE 484 473 473 ILE ILE A . n 
A 1 485 MET 485 474 474 MET MET A . n 
A 1 486 THR 486 475 475 THR THR A . n 
A 1 487 PHE 487 476 476 PHE PHE A . n 
A 1 488 ILE 488 477 477 ILE ILE A . n 
A 1 489 PHE 489 478 478 PHE PHE A . n 
A 1 490 THR 490 479 479 THR THR A . n 
A 1 491 ILE 491 480 480 ILE ILE A . n 
A 1 492 VAL 492 481 481 VAL VAL A . n 
A 1 493 LEU 493 482 482 LEU LEU A . n 
A 1 494 GLY 494 483 483 GLY GLY A . n 
A 1 495 LEU 495 484 484 LEU LEU A . n 
A 1 496 GLY 496 485 485 GLY GLY A . n 
A 1 497 LEU 497 486 486 LEU LEU A . n 
A 1 498 GLY 498 487 487 GLY GLY A . n 
A 1 499 LEU 499 488 488 LEU LEU A . n 
A 1 500 ALA 500 489 489 ALA ALA A . n 
A 1 501 ALA 501 490 490 ALA ALA A . n 
A 1 502 SER 502 491 491 SER SER A . n 
A 1 503 VAL 503 492 492 VAL VAL A . n 
A 1 504 ALA 504 493 493 ALA ALA A . n 
A 1 505 PHE 505 494 494 PHE PHE A . n 
A 1 506 GLN 506 495 495 GLN GLN A . n 
A 1 507 LEU 507 496 496 LEU LEU A . n 
A 1 508 LEU 508 497 497 LEU LEU A . n 
A 1 509 THR 509 498 498 THR THR A . n 
A 1 510 ILE 510 499 499 ILE ILE A . n 
A 1 511 VAL 511 500 500 VAL VAL A . n 
A 1 512 PHE 512 501 501 PHE PHE A . n 
A 1 513 ARG 513 502 502 ARG ARG A . n 
A 1 514 THR 514 503 503 THR THR A . n 
A 1 515 GLN 515 504 504 GLN GLN A . n 
A 1 516 PHE 516 505 505 PHE PHE A . n 
A 1 517 PRO 517 506 506 PRO PRO A . n 
A 1 518 LYS 518 507 507 LYS LYS A . n 
A 1 519 CYS 519 508 508 CYS CYS A . n 
A 1 520 SER 520 509 509 SER SER A . n 
A 1 521 THR 521 510 510 THR THR A . n 
A 1 522 LEU 522 511 511 LEU LEU A . n 
A 1 523 ALA 523 512 512 ALA ALA A . n 
A 1 524 ASN 524 513 513 ASN ASN A . n 
A 1 525 ILE 525 514 514 ILE ILE A . n 
A 1 526 GLY 526 515 515 GLY GLY A . n 
A 1 527 ARG 527 516 516 ARG ARG A . n 
A 1 528 THR 528 517 517 THR THR A . n 
A 1 529 ASN 529 518 518 ASN ASN A . n 
A 1 530 ILE 530 519 519 ILE ILE A . n 
A 1 531 TYR 531 520 520 TYR TYR A . n 
A 1 532 LYS 532 521 521 LYS LYS A . n 
A 1 533 ASN 533 522 522 ASN ASN A . n 
A 1 534 LYS 534 523 523 LYS LYS A . n 
A 1 535 LYS 535 524 524 LYS LYS A . n 
A 1 536 ASP 536 525 525 ASP ASP A . n 
A 1 537 TYR 537 526 526 TYR TYR A . n 
A 1 538 TYR 538 527 527 TYR TYR A . n 
A 1 539 ASP 539 528 528 ASP ASP A . n 
A 1 540 MET 540 529 529 MET MET A . n 
A 1 541 TYR 541 530 530 TYR TYR A . n 
A 1 542 GLU 542 531 531 GLU GLU A . n 
A 1 543 PRO 543 532 532 PRO PRO A . n 
A 1 544 GLU 544 533 533 GLU GLU A . n 
A 1 545 GLY 545 534 534 GLY GLY A . n 
A 1 546 VAL 546 535 535 VAL VAL A . n 
A 1 547 LYS 547 536 536 LYS LYS A . n 
A 1 548 ILE 548 537 537 ILE ILE A . n 
A 1 549 PHE 549 538 538 PHE PHE A . n 
A 1 550 ARG 550 539 539 ARG ARG A . n 
A 1 551 CYS 551 540 540 CYS CYS A . n 
A 1 552 PRO 552 541 541 PRO PRO A . n 
A 1 553 SER 553 542 542 SER SER A . n 
A 1 554 PRO 554 543 543 PRO PRO A . n 
A 1 555 ILE 555 544 544 ILE ILE A . n 
A 1 556 TYR 556 545 545 TYR TYR A . n 
A 1 557 PHE 557 546 546 PHE PHE A . n 
A 1 558 ALA 558 547 547 ALA ALA A . n 
A 1 559 ASN 559 548 548 ASN ASN A . n 
A 1 560 ILE 560 549 549 ILE ILE A . n 
A 1 561 GLY 561 550 550 GLY GLY A . n 
A 1 562 PHE 562 551 551 PHE PHE A . n 
A 1 563 PHE 563 552 552 PHE PHE A . n 
A 1 564 ARG 564 553 553 ARG ARG A . n 
A 1 565 ARG 565 554 554 ARG ARG A . n 
A 1 566 LYS 566 555 555 LYS LYS A . n 
A 1 567 LEU 567 556 556 LEU LEU A . n 
A 1 568 ILE 568 557 557 ILE ILE A . n 
A 1 569 ASP 569 558 558 ASP ASP A . n 
A 1 570 ALA 570 559 559 ALA ALA A . n 
A 1 571 VAL 571 560 560 VAL VAL A . n 
A 1 572 GLY 572 561 561 GLY GLY A . n 
A 1 573 PHE 573 562 562 PHE PHE A . n 
A 1 574 SER 574 563 563 SER SER A . n 
A 1 575 PRO 575 564 564 PRO PRO A . n 
A 1 576 LEU 576 565 565 LEU LEU A . n 
A 1 577 ARG 577 566 566 ARG ARG A . n 
A 1 578 ILE 578 567 567 ILE ILE A . n 
A 1 579 LEU 579 568 568 LEU LEU A . n 
A 1 580 ARG 580 569 569 ARG ARG A . n 
A 1 581 LYS 581 570 570 LYS LYS A . n 
A 1 582 ARG 582 571 571 ARG ARG A . n 
A 1 583 ASN 583 572 572 ASN ASN A . n 
A 1 584 LYS 584 573 573 LYS LYS A . n 
A 1 585 ALA 585 574 574 ALA ALA A . n 
A 1 586 LEU 586 575 575 LEU LEU A . n 
A 1 587 ARG 587 576 576 ARG ARG A . n 
A 1 588 LYS 588 577 577 LYS LYS A . n 
A 1 589 ILE 589 578 578 ILE ILE A . n 
A 1 590 ARG 590 579 579 ARG ARG A . n 
A 1 591 LYS 591 580 580 LYS LYS A . n 
A 1 592 LEU 592 581 581 LEU LEU A . n 
A 1 593 GLN 593 582 582 GLN GLN A . n 
A 1 594 LYS 594 583 583 LYS LYS A . n 
A 1 595 GLN 595 584 584 GLN GLN A . n 
A 1 596 GLY 596 585 585 GLY GLY A . n 
A 1 597 LEU 597 586 586 LEU LEU A . n 
A 1 598 LEU 598 587 587 LEU LEU A . n 
A 1 599 GLN 599 588 588 GLN GLN A . n 
A 1 600 VAL 600 589 589 VAL VAL A . n 
A 1 601 THR 601 590 590 THR THR A . n 
A 1 602 PRO 602 591 591 PRO PRO A . n 
A 1 603 LYS 603 592 592 LYS LYS A . n 
A 1 604 GLY 604 593 593 GLY GLY A . n 
A 1 605 PHE 605 594 594 PHE PHE A . n 
A 1 606 ILE 606 595 595 ILE ILE A . n 
A 1 607 CYS 607 596 596 CYS CYS A . n 
A 1 608 THR 608 597 597 THR THR A . n 
A 1 609 VAL 609 598 598 VAL VAL A . n 
A 1 610 ASP 610 599 599 ASP ASP A . n 
A 1 611 THR 611 600 600 THR THR A . n 
A 1 612 ILE 612 601 601 ILE ILE A . n 
A 1 613 LYS 613 602 602 LYS LYS A . n 
A 1 614 ASP 614 603 603 ASP ASP A . n 
A 1 615 SER 615 604 604 SER SER A . n 
A 1 616 ASP 616 605 605 ASP ASP A . n 
A 1 617 GLU 617 606 606 GLU GLU A . n 
A 1 618 GLU 618 607 607 GLU GLU A . n 
A 1 619 LEU 619 608 608 LEU LEU A . n 
A 1 620 ASP 620 609 609 ASP ASP A . n 
A 1 621 ASN 621 610 610 ASN ASN A . n 
A 1 622 ASN 622 611 611 ASN ASN A . n 
A 1 623 GLN 623 612 612 GLN GLN A . n 
A 1 624 ILE 624 613 613 ILE ILE A . n 
A 1 625 GLU 625 614 614 GLU GLU A . n 
A 1 626 VAL 626 615 615 VAL VAL A . n 
A 1 627 LEU 627 616 616 LEU LEU A . n 
A 1 628 ASP 628 617 617 ASP ASP A . n 
A 1 629 GLN 629 618 618 GLN GLN A . n 
A 1 630 PRO 630 619 619 PRO PRO A . n 
A 1 631 ILE 631 620 620 ILE ILE A . n 
A 1 632 ASN 632 621 621 ASN ASN A . n 
A 1 633 THR 633 622 622 THR THR A . n 
A 1 634 THR 634 623 623 THR THR A . n 
A 1 635 ASP 635 624 624 ASP ASP A . n 
A 1 636 LEU 636 625 625 LEU LEU A . n 
A 1 637 PRO 637 626 626 PRO PRO A . n 
A 1 638 PHE 638 627 627 PHE PHE A . n 
A 1 639 HIS 639 628 628 HIS HIS A . n 
A 1 640 ILE 640 629 629 ILE ILE A . n 
A 1 641 ASP 641 630 630 ASP ASP A . n 
A 1 642 TRP 642 631 631 TRP TRP A . n 
A 1 643 ASN 643 632 632 ASN ASN A . n 
A 1 644 ASP 644 633 633 ASP ASP A . n 
A 1 645 ASP 645 634 634 ASP ASP A . n 
A 1 646 LEU 646 635 635 LEU LEU A . n 
A 1 647 PRO 647 636 636 PRO PRO A . n 
A 1 648 LEU 648 637 637 LEU LEU A . n 
A 1 649 ASN 649 638 638 ASN ASN A . n 
A 1 650 ILE 650 639 639 ILE ILE A . n 
A 1 651 GLU 651 640 640 GLU GLU A . n 
A 1 652 VAL 652 641 641 VAL VAL A . n 
A 1 653 PRO 653 642 642 PRO PRO A . n 
A 1 654 LYS 654 643 643 LYS LYS A . n 
A 1 655 ILE 655 644 644 ILE ILE A . n 
A 1 656 SER 656 645 645 SER SER A . n 
A 1 657 LEU 657 646 646 LEU LEU A . n 
A 1 658 HIS 658 647 647 HIS HIS A . n 
A 1 659 SER 659 648 648 SER SER A . n 
A 1 660 LEU 660 649 649 LEU LEU A . n 
A 1 661 ILE 661 650 650 ILE ILE A . n 
A 1 662 LEU 662 651 651 LEU LEU A . n 
A 1 663 ASP 663 652 652 ASP ASP A . n 
A 1 664 PHE 664 653 653 PHE PHE A . n 
A 1 665 SER 665 654 654 SER SER A . n 
A 1 666 ALA 666 655 655 ALA ALA A . n 
A 1 667 VAL 667 656 656 VAL VAL A . n 
A 1 668 SER 668 657 657 SER SER A . n 
A 1 669 PHE 669 658 658 PHE PHE A . n 
A 1 670 LEU 670 659 659 LEU LEU A . n 
A 1 671 ASP 671 660 660 ASP ASP A . n 
A 1 672 VAL 672 661 661 VAL VAL A . n 
A 1 673 SER 673 662 662 SER SER A . n 
A 1 674 SER 674 663 663 SER SER A . n 
A 1 675 VAL 675 664 664 VAL VAL A . n 
A 1 676 ARG 676 665 665 ARG ARG A . n 
A 1 677 GLY 677 666 666 GLY GLY A . n 
A 1 678 LEU 678 667 667 LEU LEU A . n 
A 1 679 LYS 679 668 668 LYS LYS A . n 
A 1 680 SER 680 669 669 SER SER A . n 
A 1 681 ILE 681 670 670 ILE ILE A . n 
A 1 682 LEU 682 671 671 LEU LEU A . n 
A 1 683 GLN 683 672 672 GLN GLN A . n 
A 1 684 GLU 684 673 673 GLU GLU A . n 
A 1 685 PHE 685 674 674 PHE PHE A . n 
A 1 686 ILE 686 675 675 ILE ILE A . n 
A 1 687 ARG 687 676 676 ARG ARG A . n 
A 1 688 ILE 688 677 677 ILE ILE A . n 
A 1 689 LYS 689 678 678 LYS LYS A . n 
A 1 690 VAL 690 679 679 VAL VAL A . n 
A 1 691 ASP 691 680 680 ASP ASP A . n 
A 1 692 VAL 692 681 681 VAL VAL A . n 
A 1 693 TYR 693 682 682 TYR TYR A . n 
A 1 694 ILE 694 683 683 ILE ILE A . n 
A 1 695 VAL 695 684 684 VAL VAL A . n 
A 1 696 GLY 696 685 685 GLY GLY A . n 
A 1 697 THR 697 686 686 THR THR A . n 
A 1 698 ASP 698 687 687 ASP ASP A . n 
A 1 699 ASP 699 688 688 ASP ASP A . n 
A 1 700 ASP 700 689 689 ASP ASP A . n 
A 1 701 PHE 701 690 690 PHE PHE A . n 
A 1 702 ILE 702 691 691 ILE ILE A . n 
A 1 703 GLU 703 692 692 GLU GLU A . n 
A 1 704 LYS 704 693 693 LYS LYS A . n 
A 1 705 LEU 705 694 694 LEU LEU A . n 
A 1 706 ASN 706 695 695 ASN ASN A . n 
A 1 707 ARG 707 696 696 ARG ARG A . n 
A 1 708 TYR 708 697 697 TYR TYR A . n 
A 1 709 GLU 709 698 698 GLU GLU A . n 
A 1 710 PHE 710 699 699 PHE PHE A . n 
A 1 711 PHE 711 700 700 PHE PHE A . n 
A 1 712 ASP 712 701 701 ASP ASP A . n 
A 1 713 GLY 713 702 702 GLY GLY A . n 
A 1 714 GLU 714 703 703 GLU GLU A . n 
A 1 715 VAL 715 704 704 VAL VAL A . n 
A 1 716 LYS 716 705 705 LYS LYS A . n 
A 1 717 SER 717 706 706 SER SER A . n 
A 1 718 SER 718 707 707 SER SER A . n 
A 1 719 ILE 719 708 708 ILE ILE A . n 
A 1 720 PHE 720 709 709 PHE PHE A . n 
A 1 721 PHE 721 710 710 PHE PHE A . n 
A 1 722 LEU 722 711 711 LEU LEU A . n 
A 1 723 THR 723 712 712 THR THR A . n 
A 1 724 ILE 724 713 713 ILE ILE A . n 
A 1 725 HIS 725 714 714 HIS HIS A . n 
A 1 726 ASP 726 715 715 ASP ASP A . n 
A 1 727 ALA 727 716 716 ALA ALA A . n 
A 1 728 VAL 728 717 717 VAL VAL A . n 
A 1 729 LEU 729 718 718 LEU LEU A . n 
A 1 730 HIS 730 719 719 HIS HIS A . n 
A 1 731 ILE 731 720 720 ILE ILE A . n 
A 1 732 LEU 732 721 721 LEU LEU A . n 
A 1 733 MET 733 722 722 MET MET A . n 
A 1 734 LYS 734 723 723 LYS LYS A . n 
A 1 735 LYS 735 724 724 LYS LYS A . n 
A 1 736 ASP 736 725 725 ASP ASP A . n 
A 1 737 TYR 737 726 ?   ?   ?   A . n 
A 1 738 SER 738 727 ?   ?   ?   A . n 
A 1 739 THR 739 728 ?   ?   ?   A . n 
A 1 740 SER 740 729 ?   ?   ?   A . n 
A 1 741 LYS 741 730 ?   ?   ?   A . n 
A 1 742 PHE 742 731 ?   ?   ?   A . n 
A 1 743 ASN 743 732 ?   ?   ?   A . n 
A 1 744 PRO 744 733 ?   ?   ?   A . n 
A 1 745 SER 745 734 ?   ?   ?   A . n 
A 1 746 GLN 746 735 ?   ?   ?   A . n 
A 1 747 GLU 747 736 ?   ?   ?   A . n 
A 1 748 LYS 748 737 ?   ?   ?   A . n 
A 1 749 ASP 749 738 ?   ?   ?   A . n 
A 1 750 GLY 750 739 ?   ?   ?   A . n 
A 1 751 LYS 751 740 ?   ?   ?   A . n 
A 1 752 ILE 752 741 ?   ?   ?   A . n 
A 1 753 ASP 753 742 ?   ?   ?   A . n 
A 1 754 PHE 754 743 ?   ?   ?   A . n 
A 1 755 THR 755 744 ?   ?   ?   A . n 
A 1 756 ILE 756 745 ?   ?   ?   A . n 
A 1 757 ASN 757 746 ?   ?   ?   A . n 
A 1 758 THR 758 747 ?   ?   ?   A . n 
A 1 759 ASN 759 748 ?   ?   ?   A . n 
A 1 760 GLY 760 749 ?   ?   ?   A . n 
A 1 761 GLY 761 750 ?   ?   ?   A . n 
A 1 762 LEU 762 751 ?   ?   ?   A . n 
A 1 763 ARG 763 752 ?   ?   ?   A . n 
A 1 764 ASN 764 753 ?   ?   ?   A . n 
A 1 765 ARG 765 754 ?   ?   ?   A . n 
A 1 766 VAL 766 755 ?   ?   ?   A . n 
A 1 767 TYR 767 756 ?   ?   ?   A . n 
A 1 768 GLU 768 757 ?   ?   ?   A . n 
A 1 769 VAL 769 758 ?   ?   ?   A . n 
A 1 770 PRO 770 759 ?   ?   ?   A . n 
A 1 771 VAL 771 760 ?   ?   ?   A . n 
A 1 772 GLU 772 761 ?   ?   ?   A . n 
A 1 773 THR 773 762 ?   ?   ?   A . n 
A 1 774 LYS 774 763 ?   ?   ?   A . n 
A 1 775 PHE 775 764 ?   ?   ?   A . n 
B 1 1   MET 1   -10 ?   ?   ?   B . n 
B 1 2   ASP 2   -9  ?   ?   ?   B . n 
B 1 3   TYR 3   -8  ?   ?   ?   B . n 
B 1 4   LYS 4   -7  ?   ?   ?   B . n 
B 1 5   ASP 5   -6  ?   ?   ?   B . n 
B 1 6   ASP 6   -5  ?   ?   ?   B . n 
B 1 7   ASP 7   -4  ?   ?   ?   B . n 
B 1 8   ASP 8   -3  ?   ?   ?   B . n 
B 1 9   LYS 9   -2  ?   ?   ?   B . n 
B 1 10  GLY 10  -1  ?   ?   ?   B . n 
B 1 11  THR 11  0   ?   ?   ?   B . n 
B 1 12  MET 12  1   ?   ?   ?   B . n 
B 1 13  ILE 13  2   ?   ?   ?   B . n 
B 1 14  GLU 14  3   ?   ?   ?   B . n 
B 1 15  PRO 15  4   ?   ?   ?   B . n 
B 1 16  PHE 16  5   ?   ?   ?   B . n 
B 1 17  GLY 17  6   ?   ?   ?   B . n 
B 1 18  ASN 18  7   7   ASN ASN B . n 
B 1 19  GLN 19  8   8   GLN GLN B . n 
B 1 20  TYR 20  9   9   TYR TYR B . n 
B 1 21  ILE 21  10  10  ILE ILE B . n 
B 1 22  VAL 22  11  11  VAL VAL B . n 
B 1 23  ALA 23  12  12  ALA ALA B . n 
B 1 24  ARG 24  13  13  ARG ARG B . n 
B 1 25  PRO 25  14  14  PRO PRO B . n 
B 1 26  VAL 26  15  15  VAL VAL B . n 
B 1 27  TYR 27  16  16  TYR TYR B . n 
B 1 28  SER 28  17  17  SER SER B . n 
B 1 29  THR 29  18  18  THR THR B . n 
B 1 30  ASN 30  19  19  ASN ASN B . n 
B 1 31  ALA 31  20  20  ALA ALA B . n 
B 1 32  PHE 32  21  21  PHE PHE B . n 
B 1 33  GLU 33  22  22  GLU GLU B . n 
B 1 34  GLU 34  23  23  GLU GLU B . n 
B 1 35  ASN 35  24  24  ASN ASN B . n 
B 1 36  HIS 36  25  25  HIS HIS B . n 
B 1 37  LYS 37  26  26  LYS LYS B . n 
B 1 38  LYS 38  27  27  LYS LYS B . n 
B 1 39  THR 39  28  28  THR THR B . n 
B 1 40  GLY 40  29  29  GLY GLY B . n 
B 1 41  ARG 41  30  30  ARG ARG B . n 
B 1 42  HIS 42  31  31  HIS HIS B . n 
B 1 43  HIS 43  32  32  HIS HIS B . n 
B 1 44  LYS 44  33  33  LYS LYS B . n 
B 1 45  THR 45  34  34  THR THR B . n 
B 1 46  PHE 46  35  35  PHE PHE B . n 
B 1 47  LEU 47  36  36  LEU LEU B . n 
B 1 48  ASP 48  37  37  ASP ASP B . n 
B 1 49  HIS 49  38  38  HIS HIS B . n 
B 1 50  LEU 50  39  39  LEU LEU B . n 
B 1 51  LYS 51  40  40  LYS LYS B . n 
B 1 52  VAL 52  41  41  VAL VAL B . n 
B 1 53  CYS 53  42  42  CYS CYS B . n 
B 1 54  CYS 54  43  43  CYS CYS B . n 
B 1 55  SER 55  44  44  SER SER B . n 
B 1 56  CYS 56  45  45  CYS CYS B . n 
B 1 57  SER 57  46  46  SER SER B . n 
B 1 58  PRO 58  47  47  PRO PRO B . n 
B 1 59  GLN 59  48  48  GLN GLN B . n 
B 1 60  LYS 60  49  49  LYS LYS B . n 
B 1 61  ALA 61  50  50  ALA ALA B . n 
B 1 62  LYS 62  51  51  LYS LYS B . n 
B 1 63  ARG 63  52  52  ARG ARG B . n 
B 1 64  ILE 64  53  53  ILE ILE B . n 
B 1 65  VAL 65  54  54  VAL VAL B . n 
B 1 66  LEU 66  55  55  LEU LEU B . n 
B 1 67  SER 67  56  56  SER SER B . n 
B 1 68  LEU 68  57  57  LEU LEU B . n 
B 1 69  PHE 69  58  58  PHE PHE B . n 
B 1 70  PRO 70  59  59  PRO PRO B . n 
B 1 71  ILE 71  60  60  ILE ILE B . n 
B 1 72  ALA 72  61  61  ALA ALA B . n 
B 1 73  SER 73  62  62  SER SER B . n 
B 1 74  TRP 74  63  63  TRP TRP B . n 
B 1 75  LEU 75  64  64  LEU LEU B . n 
B 1 76  PRO 76  65  65  PRO PRO B . n 
B 1 77  ALA 77  66  66  ALA ALA B . n 
B 1 78  TYR 78  67  67  TYR TYR B . n 
B 1 79  ARG 79  68  68  ARG ARG B . n 
B 1 80  LEU 80  69  69  LEU LEU B . n 
B 1 81  LYS 81  70  70  LYS LYS B . n 
B 1 82  GLU 82  71  71  GLU GLU B . n 
B 1 83  TRP 83  72  72  TRP TRP B . n 
B 1 84  LEU 84  73  73  LEU LEU B . n 
B 1 85  LEU 85  74  74  LEU LEU B . n 
B 1 86  SER 86  75  75  SER SER B . n 
B 1 87  ASP 87  76  76  ASP ASP B . n 
B 1 88  ILE 88  77  77  ILE ILE B . n 
B 1 89  VAL 89  78  78  VAL VAL B . n 
B 1 90  SER 90  79  79  SER SER B . n 
B 1 91  GLY 91  80  80  GLY GLY B . n 
B 1 92  ILE 92  81  81  ILE ILE B . n 
B 1 93  SER 93  82  82  SER SER B . n 
B 1 94  THR 94  83  83  THR THR B . n 
B 1 95  GLY 95  84  84  GLY GLY B . n 
B 1 96  ILE 96  85  85  ILE ILE B . n 
B 1 97  VAL 97  86  86  VAL VAL B . n 
B 1 98  ALA 98  87  87  ALA ALA B . n 
B 1 99  VAL 99  88  88  VAL VAL B . n 
B 1 100 LEU 100 89  89  LEU LEU B . n 
B 1 101 GLN 101 90  90  GLN GLN B . n 
B 1 102 GLY 102 91  91  GLY GLY B . n 
B 1 103 LEU 103 92  92  LEU LEU B . n 
B 1 104 ALA 104 93  93  ALA ALA B . n 
B 1 105 PHE 105 94  94  PHE PHE B . n 
B 1 106 ALA 106 95  95  ALA ALA B . n 
B 1 107 LEU 107 96  96  LEU LEU B . n 
B 1 108 LEU 108 97  97  LEU LEU B . n 
B 1 109 VAL 109 98  98  VAL VAL B . n 
B 1 110 ASP 110 99  99  ASP ASP B . n 
B 1 111 ILE 111 100 100 ILE ILE B . n 
B 1 112 PRO 112 101 101 PRO PRO B . n 
B 1 113 PRO 113 102 102 PRO PRO B . n 
B 1 114 VAL 114 103 103 VAL VAL B . n 
B 1 115 TYR 115 104 104 TYR TYR B . n 
B 1 116 GLY 116 105 105 GLY GLY B . n 
B 1 117 LEU 117 106 106 LEU LEU B . n 
B 1 118 TYR 118 107 107 TYR TYR B . n 
B 1 119 ALA 119 108 108 ALA ALA B . n 
B 1 120 SER 120 109 109 SER SER B . n 
B 1 121 PHE 121 110 110 PHE PHE B . n 
B 1 122 PHE 122 111 111 PHE PHE B . n 
B 1 123 PRO 123 112 112 PRO PRO B . n 
B 1 124 ALA 124 113 113 ALA ALA B . n 
B 1 125 ILE 125 114 114 ILE ILE B . n 
B 1 126 ILE 126 115 115 ILE ILE B . n 
B 1 127 TYR 127 116 116 TYR TYR B . n 
B 1 128 LEU 128 117 117 LEU LEU B . n 
B 1 129 PHE 129 118 118 PHE PHE B . n 
B 1 130 PHE 130 119 119 PHE PHE B . n 
B 1 131 GLY 131 120 120 GLY GLY B . n 
B 1 132 THR 132 121 121 THR THR B . n 
B 1 133 SER 133 122 122 SER SER B . n 
B 1 134 ARG 134 123 123 ARG ARG B . n 
B 1 135 HIS 135 124 124 HIS HIS B . n 
B 1 136 ILE 136 125 125 ILE ILE B . n 
B 1 137 SER 137 126 126 SER SER B . n 
B 1 138 VAL 138 127 127 VAL VAL B . n 
B 1 139 GLY 139 128 128 GLY GLY B . n 
B 1 140 PRO 140 129 129 PRO PRO B . n 
B 1 141 PHE 141 130 130 PHE PHE B . n 
B 1 142 PRO 142 131 131 PRO PRO B . n 
B 1 143 ILE 143 132 132 ILE ILE B . n 
B 1 144 LEU 144 133 133 LEU LEU B . n 
B 1 145 SER 145 134 134 SER SER B . n 
B 1 146 MET 146 135 135 MET MET B . n 
B 1 147 MET 147 136 136 MET MET B . n 
B 1 148 VAL 148 137 137 VAL VAL B . n 
B 1 149 GLY 149 138 138 GLY GLY B . n 
B 1 150 LEU 150 139 139 LEU LEU B . n 
B 1 151 ALA 151 140 140 ALA ALA B . n 
B 1 152 VAL 152 141 141 VAL VAL B . n 
B 1 153 SER 153 142 142 SER SER B . n 
B 1 154 GLY 154 143 143 GLY GLY B . n 
B 1 155 ALA 155 144 144 ALA ALA B . n 
B 1 156 VAL 156 145 145 VAL VAL B . n 
B 1 157 SER 157 146 146 SER SER B . n 
B 1 158 LYS 158 147 147 LYS LYS B . n 
B 1 159 ALA 159 148 148 ALA ALA B . n 
B 1 160 VAL 160 149 149 VAL VAL B . n 
B 1 161 PRO 161 150 150 PRO PRO B . n 
B 1 162 ASP 162 151 ?   ?   ?   B . n 
B 1 163 ARG 163 152 ?   ?   ?   B . n 
B 1 164 ASN 164 153 ?   ?   ?   B . n 
B 1 165 ALA 165 154 ?   ?   ?   B . n 
B 1 166 THR 166 155 ?   ?   ?   B . n 
B 1 167 THR 167 156 ?   ?   ?   B . n 
B 1 168 LEU 168 157 ?   ?   ?   B . n 
B 1 169 GLY 169 158 ?   ?   ?   B . n 
B 1 170 LEU 170 159 ?   ?   ?   B . n 
B 1 171 PRO 171 160 ?   ?   ?   B . n 
B 1 172 ASN 172 161 ?   ?   ?   B . n 
B 1 173 ASN 173 162 ?   ?   ?   B . n 
B 1 174 SER 174 163 ?   ?   ?   B . n 
B 1 175 ASN 175 164 ?   ?   ?   B . n 
B 1 176 ASN 176 165 ?   ?   ?   B . n 
B 1 177 SER 177 166 ?   ?   ?   B . n 
B 1 178 SER 178 167 ?   ?   ?   B . n 
B 1 179 LEU 179 168 ?   ?   ?   B . n 
B 1 180 LEU 180 169 169 LEU LEU B . n 
B 1 181 ASP 181 170 170 ASP ASP B . n 
B 1 182 ASP 182 171 171 ASP ASP B . n 
B 1 183 GLU 183 172 172 GLU GLU B . n 
B 1 184 ARG 184 173 173 ARG ARG B . n 
B 1 185 VAL 185 174 174 VAL VAL B . n 
B 1 186 ARG 186 175 175 ARG ARG B . n 
B 1 187 VAL 187 176 176 VAL VAL B . n 
B 1 188 ALA 188 177 177 ALA ALA B . n 
B 1 189 ALA 189 178 178 ALA ALA B . n 
B 1 190 ALA 190 179 179 ALA ALA B . n 
B 1 191 ALA 191 180 180 ALA ALA B . n 
B 1 192 SER 192 181 181 SER SER B . n 
B 1 193 VAL 193 182 182 VAL VAL B . n 
B 1 194 THR 194 183 183 THR THR B . n 
B 1 195 VAL 195 184 184 VAL VAL B . n 
B 1 196 LEU 196 185 185 LEU LEU B . n 
B 1 197 SER 197 186 186 SER SER B . n 
B 1 198 GLY 198 187 187 GLY GLY B . n 
B 1 199 ILE 199 188 188 ILE ILE B . n 
B 1 200 ILE 200 189 189 ILE ILE B . n 
B 1 201 GLN 201 190 190 GLN GLN B . n 
B 1 202 LEU 202 191 191 LEU LEU B . n 
B 1 203 ALA 203 192 192 ALA ALA B . n 
B 1 204 PHE 204 193 193 PHE PHE B . n 
B 1 205 GLY 205 194 194 GLY GLY B . n 
B 1 206 ILE 206 195 195 ILE ILE B . n 
B 1 207 LEU 207 196 196 LEU LEU B . n 
B 1 208 ARG 208 197 197 ARG ARG B . n 
B 1 209 ILE 209 198 198 ILE ILE B . n 
B 1 210 GLY 210 199 199 GLY GLY B . n 
B 1 211 PHE 211 200 200 PHE PHE B . n 
B 1 212 VAL 212 201 201 VAL VAL B . n 
B 1 213 VAL 213 202 202 VAL VAL B . n 
B 1 214 ILE 214 203 203 ILE ILE B . n 
B 1 215 TYR 215 204 204 TYR TYR B . n 
B 1 216 LEU 216 205 205 LEU LEU B . n 
B 1 217 SER 217 206 206 SER SER B . n 
B 1 218 GLU 218 207 207 GLU GLU B . n 
B 1 219 SER 219 208 208 SER SER B . n 
B 1 220 LEU 220 209 209 LEU LEU B . n 
B 1 221 ILE 221 210 210 ILE ILE B . n 
B 1 222 SER 222 211 211 SER SER B . n 
B 1 223 GLY 223 212 212 GLY GLY B . n 
B 1 224 PHE 224 213 213 PHE PHE B . n 
B 1 225 THR 225 214 214 THR THR B . n 
B 1 226 THR 226 215 215 THR THR B . n 
B 1 227 ALA 227 216 216 ALA ALA B . n 
B 1 228 ALA 228 217 217 ALA ALA B . n 
B 1 229 ALA 229 218 218 ALA ALA B . n 
B 1 230 VAL 230 219 219 VAL VAL B . n 
B 1 231 HIS 231 220 220 HIS HIS B . n 
B 1 232 VAL 232 221 221 VAL VAL B . n 
B 1 233 LEU 233 222 222 LEU LEU B . n 
B 1 234 VAL 234 223 223 VAL VAL B . n 
B 1 235 SER 235 224 224 SER SER B . n 
B 1 236 GLN 236 225 225 GLN GLN B . n 
B 1 237 LEU 237 226 226 LEU LEU B . n 
B 1 238 LYS 238 227 227 LYS LYS B . n 
B 1 239 PHE 239 228 228 PHE PHE B . n 
B 1 240 ILE 240 229 229 ILE ILE B . n 
B 1 241 PHE 241 230 230 PHE PHE B . n 
B 1 242 GLN 242 231 231 GLN GLN B . n 
B 1 243 LEU 243 232 232 LEU LEU B . n 
B 1 244 THR 244 233 233 THR THR B . n 
B 1 245 VAL 245 234 234 VAL VAL B . n 
B 1 246 PRO 246 235 235 PRO PRO B . n 
B 1 247 SER 247 236 236 SER SER B . n 
B 1 248 HIS 248 237 237 HIS HIS B . n 
B 1 249 THR 249 238 238 THR THR B . n 
B 1 250 ASP 250 239 239 ASP ASP B . n 
B 1 251 PRO 251 240 240 PRO PRO B . n 
B 1 252 VAL 252 241 241 VAL VAL B . n 
B 1 253 SER 253 242 242 SER SER B . n 
B 1 254 ILE 254 243 243 ILE ILE B . n 
B 1 255 PHE 255 244 244 PHE PHE B . n 
B 1 256 LYS 256 245 245 LYS LYS B . n 
B 1 257 VAL 257 246 246 VAL VAL B . n 
B 1 258 LEU 258 247 247 LEU LEU B . n 
B 1 259 TYR 259 248 248 TYR TYR B . n 
B 1 260 SER 260 249 249 SER SER B . n 
B 1 261 VAL 261 250 250 VAL VAL B . n 
B 1 262 PHE 262 251 251 PHE PHE B . n 
B 1 263 SER 263 252 252 SER SER B . n 
B 1 264 GLN 264 253 253 GLN GLN B . n 
B 1 265 ILE 265 254 254 ILE ILE B . n 
B 1 266 GLU 266 255 255 GLU GLU B . n 
B 1 267 LYS 267 256 256 LYS LYS B . n 
B 1 268 THR 268 257 257 THR THR B . n 
B 1 269 ASN 269 258 258 ASN ASN B . n 
B 1 270 ILE 270 259 259 ILE ILE B . n 
B 1 271 ALA 271 260 260 ALA ALA B . n 
B 1 272 ASP 272 261 261 ASP ASP B . n 
B 1 273 LEU 273 262 262 LEU LEU B . n 
B 1 274 VAL 274 263 263 VAL VAL B . n 
B 1 275 THR 275 264 264 THR THR B . n 
B 1 276 ALA 276 265 265 ALA ALA B . n 
B 1 277 LEU 277 266 266 LEU LEU B . n 
B 1 278 ILE 278 267 267 ILE ILE B . n 
B 1 279 VAL 279 268 268 VAL VAL B . n 
B 1 280 LEU 280 269 269 LEU LEU B . n 
B 1 281 LEU 281 270 270 LEU LEU B . n 
B 1 282 VAL 282 271 271 VAL VAL B . n 
B 1 283 VAL 283 272 272 VAL VAL B . n 
B 1 284 SER 284 273 273 SER SER B . n 
B 1 285 ILE 285 274 274 ILE ILE B . n 
B 1 286 VAL 286 275 275 VAL VAL B . n 
B 1 287 LYS 287 276 276 LYS LYS B . n 
B 1 288 GLU 288 277 277 GLU GLU B . n 
B 1 289 ILE 289 278 278 ILE ILE B . n 
B 1 290 ASN 290 279 279 ASN ASN B . n 
B 1 291 GLN 291 280 280 GLN GLN B . n 
B 1 292 ARG 292 281 281 ARG ARG B . n 
B 1 293 PHE 293 282 282 PHE PHE B . n 
B 1 294 LYS 294 283 283 LYS LYS B . n 
B 1 295 ASP 295 284 284 ASP ASP B . n 
B 1 296 LYS 296 285 285 LYS LYS B . n 
B 1 297 LEU 297 286 286 LEU LEU B . n 
B 1 298 PRO 298 287 287 PRO PRO B . n 
B 1 299 VAL 299 288 288 VAL VAL B . n 
B 1 300 PRO 300 289 289 PRO PRO B . n 
B 1 301 ILE 301 290 290 ILE ILE B . n 
B 1 302 PRO 302 291 291 PRO PRO B . n 
B 1 303 ILE 303 292 292 ILE ILE B . n 
B 1 304 GLU 304 293 293 GLU GLU B . n 
B 1 305 PHE 305 294 294 PHE PHE B . n 
B 1 306 ILE 306 295 295 ILE ILE B . n 
B 1 307 MET 307 296 296 MET MET B . n 
B 1 308 THR 308 297 297 THR THR B . n 
B 1 309 VAL 309 298 298 VAL VAL B . n 
B 1 310 ILE 310 299 299 ILE ILE B . n 
B 1 311 ALA 311 300 300 ALA ALA B . n 
B 1 312 ALA 312 301 301 ALA ALA B . n 
B 1 313 GLY 313 302 302 GLY GLY B . n 
B 1 314 VAL 314 303 303 VAL VAL B . n 
B 1 315 SER 315 304 304 SER SER B . n 
B 1 316 TYR 316 305 305 TYR TYR B . n 
B 1 317 GLY 317 306 306 GLY GLY B . n 
B 1 318 CYS 318 307 307 CYS CYS B . n 
B 1 319 ASP 319 308 308 ASP ASP B . n 
B 1 320 PHE 320 309 309 PHE PHE B . n 
B 1 321 LYS 321 310 310 LYS LYS B . n 
B 1 322 ASN 322 311 311 ASN ASN B . n 
B 1 323 ARG 323 312 312 ARG ARG B . n 
B 1 324 PHE 324 313 313 PHE PHE B . n 
B 1 325 LYS 325 314 314 LYS LYS B . n 
B 1 326 VAL 326 315 315 VAL VAL B . n 
B 1 327 ALA 327 316 316 ALA ALA B . n 
B 1 328 VAL 328 317 317 VAL VAL B . n 
B 1 329 VAL 329 318 318 VAL VAL B . n 
B 1 330 GLY 330 319 319 GLY GLY B . n 
B 1 331 ASP 331 320 320 ASP ASP B . n 
B 1 332 MET 332 321 321 MET MET B . n 
B 1 333 ASN 333 322 322 ASN ASN B . n 
B 1 334 PRO 334 323 323 PRO PRO B . n 
B 1 335 GLY 335 324 324 GLY GLY B . n 
B 1 336 PHE 336 325 325 PHE PHE B . n 
B 1 337 GLN 337 326 326 GLN GLN B . n 
B 1 338 PRO 338 327 327 PRO PRO B . n 
B 1 339 PRO 339 328 328 PRO PRO B . n 
B 1 340 ILE 340 329 329 ILE ILE B . n 
B 1 341 THR 341 330 330 THR THR B . n 
B 1 342 PRO 342 331 331 PRO PRO B . n 
B 1 343 ASP 343 332 332 ASP ASP B . n 
B 1 344 VAL 344 333 333 VAL VAL B . n 
B 1 345 GLU 345 334 334 GLU GLU B . n 
B 1 346 THR 346 335 335 THR THR B . n 
B 1 347 PHE 347 336 336 PHE PHE B . n 
B 1 348 GLN 348 337 337 GLN GLN B . n 
B 1 349 ASN 349 338 338 ASN ASN B . n 
B 1 350 THR 350 339 339 THR THR B . n 
B 1 351 VAL 351 340 340 VAL VAL B . n 
B 1 352 GLY 352 341 341 GLY GLY B . n 
B 1 353 ASP 353 342 342 ASP ASP B . n 
B 1 354 CYS 354 343 343 CYS CYS B . n 
B 1 355 PHE 355 344 344 PHE PHE B . n 
B 1 356 GLY 356 345 345 GLY GLY B . n 
B 1 357 ILE 357 346 346 ILE ILE B . n 
B 1 358 ALA 358 347 347 ALA ALA B . n 
B 1 359 MET 359 348 348 MET MET B . n 
B 1 360 VAL 360 349 349 VAL VAL B . n 
B 1 361 ALA 361 350 350 ALA ALA B . n 
B 1 362 PHE 362 351 351 PHE PHE B . n 
B 1 363 ALA 363 352 352 ALA ALA B . n 
B 1 364 VAL 364 353 353 VAL VAL B . n 
B 1 365 ALA 365 354 354 ALA ALA B . n 
B 1 366 PHE 366 355 355 PHE PHE B . n 
B 1 367 SER 367 356 356 SER SER B . n 
B 1 368 VAL 368 357 357 VAL VAL B . n 
B 1 369 ALA 369 358 358 ALA ALA B . n 
B 1 370 SER 370 359 359 SER SER B . n 
B 1 371 VAL 371 360 360 VAL VAL B . n 
B 1 372 TYR 372 361 361 TYR TYR B . n 
B 1 373 SER 373 362 362 SER SER B . n 
B 1 374 LEU 374 363 363 LEU LEU B . n 
B 1 375 LYS 375 364 364 LYS LYS B . n 
B 1 376 TYR 376 365 365 TYR TYR B . n 
B 1 377 ASP 377 366 366 ASP ASP B . n 
B 1 378 TYR 378 367 367 TYR TYR B . n 
B 1 379 PRO 379 368 368 PRO PRO B . n 
B 1 380 LEU 380 369 369 LEU LEU B . n 
B 1 381 ASP 381 370 370 ASP ASP B . n 
B 1 382 GLY 382 371 371 GLY GLY B . n 
B 1 383 ASN 383 372 372 ASN ASN B . n 
B 1 384 GLN 384 373 373 GLN GLN B . n 
B 1 385 GLU 385 374 374 GLU GLU B . n 
B 1 386 LEU 386 375 375 LEU LEU B . n 
B 1 387 ILE 387 376 376 ILE ILE B . n 
B 1 388 ALA 388 377 377 ALA ALA B . n 
B 1 389 LEU 389 378 378 LEU LEU B . n 
B 1 390 GLY 390 379 379 GLY GLY B . n 
B 1 391 LEU 391 380 380 LEU LEU B . n 
B 1 392 GLY 392 381 381 GLY GLY B . n 
B 1 393 ASN 393 382 382 ASN ASN B . n 
B 1 394 ILE 394 383 383 ILE ILE B . n 
B 1 395 VAL 395 384 384 VAL VAL B . n 
B 1 396 CYS 396 385 385 CYS CYS B . n 
B 1 397 GLY 397 386 386 GLY GLY B . n 
B 1 398 VAL 398 387 387 VAL VAL B . n 
B 1 399 PHE 399 388 388 PHE PHE B . n 
B 1 400 ARG 400 389 389 ARG ARG B . n 
B 1 401 GLY 401 390 390 GLY GLY B . n 
B 1 402 PHE 402 391 391 PHE PHE B . n 
B 1 403 ALA 403 392 392 ALA ALA B . n 
B 1 404 GLY 404 393 393 GLY GLY B . n 
B 1 405 SER 405 394 394 SER SER B . n 
B 1 406 THR 406 395 395 THR THR B . n 
B 1 407 ALA 407 396 396 ALA ALA B . n 
B 1 408 LEU 408 397 397 LEU LEU B . n 
B 1 409 SER 409 398 398 SER SER B . n 
B 1 410 ARG 410 399 399 ARG ARG B . n 
B 1 411 SER 411 400 400 SER SER B . n 
B 1 412 ALA 412 401 401 ALA ALA B . n 
B 1 413 VAL 413 402 402 VAL VAL B . n 
B 1 414 GLN 414 403 403 GLN GLN B . n 
B 1 415 GLU 415 404 404 GLU GLU B . n 
B 1 416 SER 416 405 405 SER SER B . n 
B 1 417 THR 417 406 406 THR THR B . n 
B 1 418 GLY 418 407 407 GLY GLY B . n 
B 1 419 GLY 419 408 408 GLY GLY B . n 
B 1 420 LYS 420 409 409 LYS LYS B . n 
B 1 421 THR 421 410 410 THR THR B . n 
B 1 422 GLN 422 411 411 GLN GLN B . n 
B 1 423 ILE 423 412 412 ILE ILE B . n 
B 1 424 ALA 424 413 413 ALA ALA B . n 
B 1 425 GLY 425 414 414 GLY GLY B . n 
B 1 426 LEU 426 415 415 LEU LEU B . n 
B 1 427 ILE 427 416 416 ILE ILE B . n 
B 1 428 GLY 428 417 417 GLY GLY B . n 
B 1 429 ALA 429 418 418 ALA ALA B . n 
B 1 430 ILE 430 419 419 ILE ILE B . n 
B 1 431 ILE 431 420 420 ILE ILE B . n 
B 1 432 VAL 432 421 421 VAL VAL B . n 
B 1 433 LEU 433 422 422 LEU LEU B . n 
B 1 434 ILE 434 423 423 ILE ILE B . n 
B 1 435 VAL 435 424 424 VAL VAL B . n 
B 1 436 VAL 436 425 425 VAL VAL B . n 
B 1 437 LEU 437 426 426 LEU LEU B . n 
B 1 438 ALA 438 427 427 ALA ALA B . n 
B 1 439 ILE 439 428 428 ILE ILE B . n 
B 1 440 GLY 440 429 429 GLY GLY B . n 
B 1 441 PHE 441 430 430 PHE PHE B . n 
B 1 442 LEU 442 431 431 LEU LEU B . n 
B 1 443 LEU 443 432 432 LEU LEU B . n 
B 1 444 ALA 444 433 433 ALA ALA B . n 
B 1 445 PRO 445 434 434 PRO PRO B . n 
B 1 446 LEU 446 435 435 LEU LEU B . n 
B 1 447 GLN 447 436 436 GLN GLN B . n 
B 1 448 LYS 448 437 437 LYS LYS B . n 
B 1 449 SER 449 438 438 SER SER B . n 
B 1 450 VAL 450 439 439 VAL VAL B . n 
B 1 451 LEU 451 440 440 LEU LEU B . n 
B 1 452 ALA 452 441 441 ALA ALA B . n 
B 1 453 ALA 453 442 442 ALA ALA B . n 
B 1 454 LEU 454 443 443 LEU LEU B . n 
B 1 455 ALA 455 444 444 ALA ALA B . n 
B 1 456 LEU 456 445 445 LEU LEU B . n 
B 1 457 GLY 457 446 446 GLY GLY B . n 
B 1 458 ASN 458 447 447 ASN ASN B . n 
B 1 459 LEU 459 448 448 LEU LEU B . n 
B 1 460 LYS 460 449 449 LYS LYS B . n 
B 1 461 GLY 461 450 450 GLY GLY B . n 
B 1 462 MET 462 451 451 MET MET B . n 
B 1 463 LEU 463 452 452 LEU LEU B . n 
B 1 464 MET 464 453 453 MET MET B . n 
B 1 465 GLN 465 454 454 GLN GLN B . n 
B 1 466 PHE 466 455 455 PHE PHE B . n 
B 1 467 ALA 467 456 456 ALA ALA B . n 
B 1 468 GLU 468 457 457 GLU GLU B . n 
B 1 469 ILE 469 458 458 ILE ILE B . n 
B 1 470 GLY 470 459 459 GLY GLY B . n 
B 1 471 ARG 471 460 460 ARG ARG B . n 
B 1 472 LEU 472 461 461 LEU LEU B . n 
B 1 473 TRP 473 462 462 TRP TRP B . n 
B 1 474 ARG 474 463 463 ARG ARG B . n 
B 1 475 LYS 475 464 464 LYS LYS B . n 
B 1 476 ASP 476 465 465 ASP ASP B . n 
B 1 477 LYS 477 466 466 LYS LYS B . n 
B 1 478 TYR 478 467 467 TYR TYR B . n 
B 1 479 ASP 479 468 468 ASP ASP B . n 
B 1 480 CYS 480 469 469 CYS CYS B . n 
B 1 481 LEU 481 470 470 LEU LEU B . n 
B 1 482 ILE 482 471 471 ILE ILE B . n 
B 1 483 TRP 483 472 472 TRP TRP B . n 
B 1 484 ILE 484 473 473 ILE ILE B . n 
B 1 485 MET 485 474 474 MET MET B . n 
B 1 486 THR 486 475 475 THR THR B . n 
B 1 487 PHE 487 476 476 PHE PHE B . n 
B 1 488 ILE 488 477 477 ILE ILE B . n 
B 1 489 PHE 489 478 478 PHE PHE B . n 
B 1 490 THR 490 479 479 THR THR B . n 
B 1 491 ILE 491 480 480 ILE ILE B . n 
B 1 492 VAL 492 481 481 VAL VAL B . n 
B 1 493 LEU 493 482 482 LEU LEU B . n 
B 1 494 GLY 494 483 483 GLY GLY B . n 
B 1 495 LEU 495 484 484 LEU LEU B . n 
B 1 496 GLY 496 485 485 GLY GLY B . n 
B 1 497 LEU 497 486 486 LEU LEU B . n 
B 1 498 GLY 498 487 487 GLY GLY B . n 
B 1 499 LEU 499 488 488 LEU LEU B . n 
B 1 500 ALA 500 489 489 ALA ALA B . n 
B 1 501 ALA 501 490 490 ALA ALA B . n 
B 1 502 SER 502 491 491 SER SER B . n 
B 1 503 VAL 503 492 492 VAL VAL B . n 
B 1 504 ALA 504 493 493 ALA ALA B . n 
B 1 505 PHE 505 494 494 PHE PHE B . n 
B 1 506 GLN 506 495 495 GLN GLN B . n 
B 1 507 LEU 507 496 496 LEU LEU B . n 
B 1 508 LEU 508 497 497 LEU LEU B . n 
B 1 509 THR 509 498 498 THR THR B . n 
B 1 510 ILE 510 499 499 ILE ILE B . n 
B 1 511 VAL 511 500 500 VAL VAL B . n 
B 1 512 PHE 512 501 501 PHE PHE B . n 
B 1 513 ARG 513 502 502 ARG ARG B . n 
B 1 514 THR 514 503 503 THR THR B . n 
B 1 515 GLN 515 504 504 GLN GLN B . n 
B 1 516 PHE 516 505 505 PHE PHE B . n 
B 1 517 PRO 517 506 506 PRO PRO B . n 
B 1 518 LYS 518 507 507 LYS LYS B . n 
B 1 519 CYS 519 508 508 CYS CYS B . n 
B 1 520 SER 520 509 509 SER SER B . n 
B 1 521 THR 521 510 510 THR THR B . n 
B 1 522 LEU 522 511 511 LEU LEU B . n 
B 1 523 ALA 523 512 512 ALA ALA B . n 
B 1 524 ASN 524 513 513 ASN ASN B . n 
B 1 525 ILE 525 514 514 ILE ILE B . n 
B 1 526 GLY 526 515 515 GLY GLY B . n 
B 1 527 ARG 527 516 516 ARG ARG B . n 
B 1 528 THR 528 517 517 THR THR B . n 
B 1 529 ASN 529 518 518 ASN ASN B . n 
B 1 530 ILE 530 519 519 ILE ILE B . n 
B 1 531 TYR 531 520 520 TYR TYR B . n 
B 1 532 LYS 532 521 521 LYS LYS B . n 
B 1 533 ASN 533 522 522 ASN ASN B . n 
B 1 534 LYS 534 523 523 LYS LYS B . n 
B 1 535 LYS 535 524 524 LYS LYS B . n 
B 1 536 ASP 536 525 525 ASP ASP B . n 
B 1 537 TYR 537 526 526 TYR TYR B . n 
B 1 538 TYR 538 527 527 TYR TYR B . n 
B 1 539 ASP 539 528 528 ASP ASP B . n 
B 1 540 MET 540 529 529 MET MET B . n 
B 1 541 TYR 541 530 530 TYR TYR B . n 
B 1 542 GLU 542 531 531 GLU GLU B . n 
B 1 543 PRO 543 532 532 PRO PRO B . n 
B 1 544 GLU 544 533 533 GLU GLU B . n 
B 1 545 GLY 545 534 534 GLY GLY B . n 
B 1 546 VAL 546 535 535 VAL VAL B . n 
B 1 547 LYS 547 536 536 LYS LYS B . n 
B 1 548 ILE 548 537 537 ILE ILE B . n 
B 1 549 PHE 549 538 538 PHE PHE B . n 
B 1 550 ARG 550 539 539 ARG ARG B . n 
B 1 551 CYS 551 540 540 CYS CYS B . n 
B 1 552 PRO 552 541 541 PRO PRO B . n 
B 1 553 SER 553 542 542 SER SER B . n 
B 1 554 PRO 554 543 543 PRO PRO B . n 
B 1 555 ILE 555 544 544 ILE ILE B . n 
B 1 556 TYR 556 545 545 TYR TYR B . n 
B 1 557 PHE 557 546 546 PHE PHE B . n 
B 1 558 ALA 558 547 547 ALA ALA B . n 
B 1 559 ASN 559 548 548 ASN ASN B . n 
B 1 560 ILE 560 549 549 ILE ILE B . n 
B 1 561 GLY 561 550 550 GLY GLY B . n 
B 1 562 PHE 562 551 551 PHE PHE B . n 
B 1 563 PHE 563 552 552 PHE PHE B . n 
B 1 564 ARG 564 553 553 ARG ARG B . n 
B 1 565 ARG 565 554 554 ARG ARG B . n 
B 1 566 LYS 566 555 555 LYS LYS B . n 
B 1 567 LEU 567 556 556 LEU LEU B . n 
B 1 568 ILE 568 557 557 ILE ILE B . n 
B 1 569 ASP 569 558 558 ASP ASP B . n 
B 1 570 ALA 570 559 559 ALA ALA B . n 
B 1 571 VAL 571 560 560 VAL VAL B . n 
B 1 572 GLY 572 561 561 GLY GLY B . n 
B 1 573 PHE 573 562 562 PHE PHE B . n 
B 1 574 SER 574 563 563 SER SER B . n 
B 1 575 PRO 575 564 564 PRO PRO B . n 
B 1 576 LEU 576 565 565 LEU LEU B . n 
B 1 577 ARG 577 566 566 ARG ARG B . n 
B 1 578 ILE 578 567 567 ILE ILE B . n 
B 1 579 LEU 579 568 568 LEU LEU B . n 
B 1 580 ARG 580 569 569 ARG ARG B . n 
B 1 581 LYS 581 570 570 LYS LYS B . n 
B 1 582 ARG 582 571 571 ARG ARG B . n 
B 1 583 ASN 583 572 572 ASN ASN B . n 
B 1 584 LYS 584 573 573 LYS LYS B . n 
B 1 585 ALA 585 574 574 ALA ALA B . n 
B 1 586 LEU 586 575 575 LEU LEU B . n 
B 1 587 ARG 587 576 576 ARG ARG B . n 
B 1 588 LYS 588 577 577 LYS LYS B . n 
B 1 589 ILE 589 578 578 ILE ILE B . n 
B 1 590 ARG 590 579 579 ARG ARG B . n 
B 1 591 LYS 591 580 580 LYS LYS B . n 
B 1 592 LEU 592 581 581 LEU LEU B . n 
B 1 593 GLN 593 582 582 GLN GLN B . n 
B 1 594 LYS 594 583 583 LYS LYS B . n 
B 1 595 GLN 595 584 584 GLN GLN B . n 
B 1 596 GLY 596 585 585 GLY GLY B . n 
B 1 597 LEU 597 586 586 LEU LEU B . n 
B 1 598 LEU 598 587 587 LEU LEU B . n 
B 1 599 GLN 599 588 588 GLN GLN B . n 
B 1 600 VAL 600 589 589 VAL VAL B . n 
B 1 601 THR 601 590 590 THR THR B . n 
B 1 602 PRO 602 591 591 PRO PRO B . n 
B 1 603 LYS 603 592 592 LYS LYS B . n 
B 1 604 GLY 604 593 593 GLY GLY B . n 
B 1 605 PHE 605 594 594 PHE PHE B . n 
B 1 606 ILE 606 595 595 ILE ILE B . n 
B 1 607 CYS 607 596 596 CYS CYS B . n 
B 1 608 THR 608 597 597 THR THR B . n 
B 1 609 VAL 609 598 598 VAL VAL B . n 
B 1 610 ASP 610 599 599 ASP ASP B . n 
B 1 611 THR 611 600 600 THR THR B . n 
B 1 612 ILE 612 601 601 ILE ILE B . n 
B 1 613 LYS 613 602 602 LYS LYS B . n 
B 1 614 ASP 614 603 603 ASP ASP B . n 
B 1 615 SER 615 604 604 SER SER B . n 
B 1 616 ASP 616 605 605 ASP ASP B . n 
B 1 617 GLU 617 606 606 GLU GLU B . n 
B 1 618 GLU 618 607 607 GLU GLU B . n 
B 1 619 LEU 619 608 608 LEU LEU B . n 
B 1 620 ASP 620 609 609 ASP ASP B . n 
B 1 621 ASN 621 610 610 ASN ASN B . n 
B 1 622 ASN 622 611 611 ASN ASN B . n 
B 1 623 GLN 623 612 612 GLN GLN B . n 
B 1 624 ILE 624 613 613 ILE ILE B . n 
B 1 625 GLU 625 614 614 GLU GLU B . n 
B 1 626 VAL 626 615 615 VAL VAL B . n 
B 1 627 LEU 627 616 616 LEU LEU B . n 
B 1 628 ASP 628 617 617 ASP ASP B . n 
B 1 629 GLN 629 618 618 GLN GLN B . n 
B 1 630 PRO 630 619 619 PRO PRO B . n 
B 1 631 ILE 631 620 620 ILE ILE B . n 
B 1 632 ASN 632 621 621 ASN ASN B . n 
B 1 633 THR 633 622 622 THR THR B . n 
B 1 634 THR 634 623 623 THR THR B . n 
B 1 635 ASP 635 624 624 ASP ASP B . n 
B 1 636 LEU 636 625 625 LEU LEU B . n 
B 1 637 PRO 637 626 626 PRO PRO B . n 
B 1 638 PHE 638 627 627 PHE PHE B . n 
B 1 639 HIS 639 628 628 HIS HIS B . n 
B 1 640 ILE 640 629 629 ILE ILE B . n 
B 1 641 ASP 641 630 630 ASP ASP B . n 
B 1 642 TRP 642 631 631 TRP TRP B . n 
B 1 643 ASN 643 632 632 ASN ASN B . n 
B 1 644 ASP 644 633 633 ASP ASP B . n 
B 1 645 ASP 645 634 634 ASP ASP B . n 
B 1 646 LEU 646 635 635 LEU LEU B . n 
B 1 647 PRO 647 636 636 PRO PRO B . n 
B 1 648 LEU 648 637 637 LEU LEU B . n 
B 1 649 ASN 649 638 638 ASN ASN B . n 
B 1 650 ILE 650 639 639 ILE ILE B . n 
B 1 651 GLU 651 640 640 GLU GLU B . n 
B 1 652 VAL 652 641 641 VAL VAL B . n 
B 1 653 PRO 653 642 642 PRO PRO B . n 
B 1 654 LYS 654 643 643 LYS LYS B . n 
B 1 655 ILE 655 644 644 ILE ILE B . n 
B 1 656 SER 656 645 645 SER SER B . n 
B 1 657 LEU 657 646 646 LEU LEU B . n 
B 1 658 HIS 658 647 647 HIS HIS B . n 
B 1 659 SER 659 648 648 SER SER B . n 
B 1 660 LEU 660 649 649 LEU LEU B . n 
B 1 661 ILE 661 650 650 ILE ILE B . n 
B 1 662 LEU 662 651 651 LEU LEU B . n 
B 1 663 ASP 663 652 652 ASP ASP B . n 
B 1 664 PHE 664 653 653 PHE PHE B . n 
B 1 665 SER 665 654 654 SER SER B . n 
B 1 666 ALA 666 655 655 ALA ALA B . n 
B 1 667 VAL 667 656 656 VAL VAL B . n 
B 1 668 SER 668 657 657 SER SER B . n 
B 1 669 PHE 669 658 658 PHE PHE B . n 
B 1 670 LEU 670 659 659 LEU LEU B . n 
B 1 671 ASP 671 660 660 ASP ASP B . n 
B 1 672 VAL 672 661 661 VAL VAL B . n 
B 1 673 SER 673 662 662 SER SER B . n 
B 1 674 SER 674 663 663 SER SER B . n 
B 1 675 VAL 675 664 664 VAL VAL B . n 
B 1 676 ARG 676 665 665 ARG ARG B . n 
B 1 677 GLY 677 666 666 GLY GLY B . n 
B 1 678 LEU 678 667 667 LEU LEU B . n 
B 1 679 LYS 679 668 668 LYS LYS B . n 
B 1 680 SER 680 669 669 SER SER B . n 
B 1 681 ILE 681 670 670 ILE ILE B . n 
B 1 682 LEU 682 671 671 LEU LEU B . n 
B 1 683 GLN 683 672 672 GLN GLN B . n 
B 1 684 GLU 684 673 673 GLU GLU B . n 
B 1 685 PHE 685 674 674 PHE PHE B . n 
B 1 686 ILE 686 675 675 ILE ILE B . n 
B 1 687 ARG 687 676 676 ARG ARG B . n 
B 1 688 ILE 688 677 677 ILE ILE B . n 
B 1 689 LYS 689 678 678 LYS LYS B . n 
B 1 690 VAL 690 679 679 VAL VAL B . n 
B 1 691 ASP 691 680 680 ASP ASP B . n 
B 1 692 VAL 692 681 681 VAL VAL B . n 
B 1 693 TYR 693 682 682 TYR TYR B . n 
B 1 694 ILE 694 683 683 ILE ILE B . n 
B 1 695 VAL 695 684 684 VAL VAL B . n 
B 1 696 GLY 696 685 685 GLY GLY B . n 
B 1 697 THR 697 686 686 THR THR B . n 
B 1 698 ASP 698 687 687 ASP ASP B . n 
B 1 699 ASP 699 688 688 ASP ASP B . n 
B 1 700 ASP 700 689 689 ASP ASP B . n 
B 1 701 PHE 701 690 690 PHE PHE B . n 
B 1 702 ILE 702 691 691 ILE ILE B . n 
B 1 703 GLU 703 692 692 GLU GLU B . n 
B 1 704 LYS 704 693 693 LYS LYS B . n 
B 1 705 LEU 705 694 694 LEU LEU B . n 
B 1 706 ASN 706 695 695 ASN ASN B . n 
B 1 707 ARG 707 696 696 ARG ARG B . n 
B 1 708 TYR 708 697 697 TYR TYR B . n 
B 1 709 GLU 709 698 698 GLU GLU B . n 
B 1 710 PHE 710 699 699 PHE PHE B . n 
B 1 711 PHE 711 700 700 PHE PHE B . n 
B 1 712 ASP 712 701 701 ASP ASP B . n 
B 1 713 GLY 713 702 702 GLY GLY B . n 
B 1 714 GLU 714 703 703 GLU GLU B . n 
B 1 715 VAL 715 704 704 VAL VAL B . n 
B 1 716 LYS 716 705 705 LYS LYS B . n 
B 1 717 SER 717 706 706 SER SER B . n 
B 1 718 SER 718 707 707 SER SER B . n 
B 1 719 ILE 719 708 708 ILE ILE B . n 
B 1 720 PHE 720 709 709 PHE PHE B . n 
B 1 721 PHE 721 710 710 PHE PHE B . n 
B 1 722 LEU 722 711 711 LEU LEU B . n 
B 1 723 THR 723 712 712 THR THR B . n 
B 1 724 ILE 724 713 713 ILE ILE B . n 
B 1 725 HIS 725 714 714 HIS HIS B . n 
B 1 726 ASP 726 715 715 ASP ASP B . n 
B 1 727 ALA 727 716 716 ALA ALA B . n 
B 1 728 VAL 728 717 717 VAL VAL B . n 
B 1 729 LEU 729 718 718 LEU LEU B . n 
B 1 730 HIS 730 719 719 HIS HIS B . n 
B 1 731 ILE 731 720 720 ILE ILE B . n 
B 1 732 LEU 732 721 721 LEU LEU B . n 
B 1 733 MET 733 722 722 MET MET B . n 
B 1 734 LYS 734 723 723 LYS LYS B . n 
B 1 735 LYS 735 724 724 LYS LYS B . n 
B 1 736 ASP 736 725 725 ASP ASP B . n 
B 1 737 TYR 737 726 ?   ?   ?   B . n 
B 1 738 SER 738 727 ?   ?   ?   B . n 
B 1 739 THR 739 728 ?   ?   ?   B . n 
B 1 740 SER 740 729 ?   ?   ?   B . n 
B 1 741 LYS 741 730 ?   ?   ?   B . n 
B 1 742 PHE 742 731 ?   ?   ?   B . n 
B 1 743 ASN 743 732 ?   ?   ?   B . n 
B 1 744 PRO 744 733 ?   ?   ?   B . n 
B 1 745 SER 745 734 ?   ?   ?   B . n 
B 1 746 GLN 746 735 ?   ?   ?   B . n 
B 1 747 GLU 747 736 ?   ?   ?   B . n 
B 1 748 LYS 748 737 ?   ?   ?   B . n 
B 1 749 ASP 749 738 ?   ?   ?   B . n 
B 1 750 GLY 750 739 ?   ?   ?   B . n 
B 1 751 LYS 751 740 ?   ?   ?   B . n 
B 1 752 ILE 752 741 ?   ?   ?   B . n 
B 1 753 ASP 753 742 ?   ?   ?   B . n 
B 1 754 PHE 754 743 ?   ?   ?   B . n 
B 1 755 THR 755 744 ?   ?   ?   B . n 
B 1 756 ILE 756 745 ?   ?   ?   B . n 
B 1 757 ASN 757 746 ?   ?   ?   B . n 
B 1 758 THR 758 747 ?   ?   ?   B . n 
B 1 759 ASN 759 748 ?   ?   ?   B . n 
B 1 760 GLY 760 749 ?   ?   ?   B . n 
B 1 761 GLY 761 750 ?   ?   ?   B . n 
B 1 762 LEU 762 751 ?   ?   ?   B . n 
B 1 763 ARG 763 752 ?   ?   ?   B . n 
B 1 764 ASN 764 753 ?   ?   ?   B . n 
B 1 765 ARG 765 754 ?   ?   ?   B . n 
B 1 766 VAL 766 755 ?   ?   ?   B . n 
B 1 767 TYR 767 756 ?   ?   ?   B . n 
B 1 768 GLU 768 757 ?   ?   ?   B . n 
B 1 769 VAL 769 758 ?   ?   ?   B . n 
B 1 770 PRO 770 759 ?   ?   ?   B . n 
B 1 771 VAL 771 760 ?   ?   ?   B . n 
B 1 772 GLU 772 761 ?   ?   ?   B . n 
B 1 773 THR 773 762 ?   ?   ?   B . n 
B 1 774 LYS 774 763 ?   ?   ?   B . n 
B 1 775 PHE 775 764 ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        SO4 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   SO4 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 SO4 1 801 827 SO4 SO4 A . 
D 2 SO4 1 801 827 SO4 SO4 B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A LYS 26  ? CG  ? A LYS 37  CG  
2   1 Y 1 A LYS 26  ? CD  ? A LYS 37  CD  
3   1 Y 1 A LYS 26  ? CE  ? A LYS 37  CE  
4   1 Y 1 A LYS 26  ? NZ  ? A LYS 37  NZ  
5   1 Y 1 A LYS 33  ? CG  ? A LYS 44  CG  
6   1 Y 1 A LYS 33  ? CD  ? A LYS 44  CD  
7   1 Y 1 A LYS 33  ? CE  ? A LYS 44  CE  
8   1 Y 1 A LYS 33  ? NZ  ? A LYS 44  NZ  
9   1 Y 1 A LEU 36  ? CG  ? A LEU 47  CG  
10  1 Y 1 A LEU 36  ? CD1 ? A LEU 47  CD1 
11  1 Y 1 A LEU 36  ? CD2 ? A LEU 47  CD2 
12  1 Y 1 A ASP 37  ? CG  ? A ASP 48  CG  
13  1 Y 1 A ASP 37  ? OD1 ? A ASP 48  OD1 
14  1 Y 1 A ASP 37  ? OD2 ? A ASP 48  OD2 
15  1 Y 1 A SER 44  ? OG  ? A SER 55  OG  
16  1 Y 1 A LEU 169 ? CG  ? A LEU 180 CG  
17  1 Y 1 A LEU 169 ? CD1 ? A LEU 180 CD1 
18  1 Y 1 A LEU 169 ? CD2 ? A LEU 180 CD2 
19  1 Y 1 A LYS 285 ? CG  ? A LYS 296 CG  
20  1 Y 1 A LYS 285 ? CD  ? A LYS 296 CD  
21  1 Y 1 A LYS 285 ? CE  ? A LYS 296 CE  
22  1 Y 1 A LYS 285 ? NZ  ? A LYS 296 NZ  
23  1 Y 1 A LYS 583 ? CG  ? A LYS 594 CG  
24  1 Y 1 A LYS 583 ? CD  ? A LYS 594 CD  
25  1 Y 1 A LYS 583 ? CE  ? A LYS 594 CE  
26  1 Y 1 A LYS 583 ? NZ  ? A LYS 594 NZ  
27  1 Y 1 A GLN 588 ? CG  ? A GLN 599 CG  
28  1 Y 1 A GLN 588 ? CD  ? A GLN 599 CD  
29  1 Y 1 A GLN 588 ? OE1 ? A GLN 599 OE1 
30  1 Y 1 A GLN 588 ? NE2 ? A GLN 599 NE2 
31  1 Y 1 A VAL 589 ? CG1 ? A VAL 600 CG1 
32  1 Y 1 A VAL 589 ? CG2 ? A VAL 600 CG2 
33  1 Y 1 A LYS 592 ? CG  ? A LYS 603 CG  
34  1 Y 1 A LYS 592 ? CD  ? A LYS 603 CD  
35  1 Y 1 A LYS 592 ? CE  ? A LYS 603 CE  
36  1 Y 1 A LYS 592 ? NZ  ? A LYS 603 NZ  
37  1 Y 1 A ASP 599 ? CG  ? A ASP 610 CG  
38  1 Y 1 A ASP 599 ? OD1 ? A ASP 610 OD1 
39  1 Y 1 A ASP 599 ? OD2 ? A ASP 610 OD2 
40  1 Y 1 A THR 600 ? OG1 ? A THR 611 OG1 
41  1 Y 1 A THR 600 ? CG2 ? A THR 611 CG2 
42  1 Y 1 A LYS 602 ? CG  ? A LYS 613 CG  
43  1 Y 1 A LYS 602 ? CD  ? A LYS 613 CD  
44  1 Y 1 A LYS 602 ? CE  ? A LYS 613 CE  
45  1 Y 1 A LYS 602 ? NZ  ? A LYS 613 NZ  
46  1 Y 1 A ASP 603 ? CG  ? A ASP 614 CG  
47  1 Y 1 A ASP 603 ? OD1 ? A ASP 614 OD1 
48  1 Y 1 A ASP 603 ? OD2 ? A ASP 614 OD2 
49  1 Y 1 A HIS 628 ? CG  ? A HIS 639 CG  
50  1 Y 1 A HIS 628 ? ND1 ? A HIS 639 ND1 
51  1 Y 1 A HIS 628 ? CD2 ? A HIS 639 CD2 
52  1 Y 1 A HIS 628 ? CE1 ? A HIS 639 CE1 
53  1 Y 1 A HIS 628 ? NE2 ? A HIS 639 NE2 
54  1 Y 1 B LYS 26  ? CG  ? B LYS 37  CG  
55  1 Y 1 B LYS 26  ? CD  ? B LYS 37  CD  
56  1 Y 1 B LYS 26  ? CE  ? B LYS 37  CE  
57  1 Y 1 B LYS 26  ? NZ  ? B LYS 37  NZ  
58  1 Y 1 B LYS 33  ? CG  ? B LYS 44  CG  
59  1 Y 1 B LYS 33  ? CD  ? B LYS 44  CD  
60  1 Y 1 B LYS 33  ? CE  ? B LYS 44  CE  
61  1 Y 1 B LYS 33  ? NZ  ? B LYS 44  NZ  
62  1 Y 1 B LEU 36  ? CG  ? B LEU 47  CG  
63  1 Y 1 B LEU 36  ? CD1 ? B LEU 47  CD1 
64  1 Y 1 B LEU 36  ? CD2 ? B LEU 47  CD2 
65  1 Y 1 B ASP 37  ? CG  ? B ASP 48  CG  
66  1 Y 1 B ASP 37  ? OD1 ? B ASP 48  OD1 
67  1 Y 1 B ASP 37  ? OD2 ? B ASP 48  OD2 
68  1 Y 1 B LEU 169 ? CG  ? B LEU 180 CG  
69  1 Y 1 B LEU 169 ? CD1 ? B LEU 180 CD1 
70  1 Y 1 B LEU 169 ? CD2 ? B LEU 180 CD2 
71  1 Y 1 B LYS 285 ? CG  ? B LYS 296 CG  
72  1 Y 1 B LYS 285 ? CD  ? B LYS 296 CD  
73  1 Y 1 B LYS 285 ? CE  ? B LYS 296 CE  
74  1 Y 1 B LYS 285 ? NZ  ? B LYS 296 NZ  
75  1 Y 1 B LYS 583 ? CG  ? B LYS 594 CG  
76  1 Y 1 B LYS 583 ? CD  ? B LYS 594 CD  
77  1 Y 1 B LYS 583 ? CE  ? B LYS 594 CE  
78  1 Y 1 B LYS 583 ? NZ  ? B LYS 594 NZ  
79  1 Y 1 B GLN 588 ? CG  ? B GLN 599 CG  
80  1 Y 1 B GLN 588 ? CD  ? B GLN 599 CD  
81  1 Y 1 B GLN 588 ? OE1 ? B GLN 599 OE1 
82  1 Y 1 B GLN 588 ? NE2 ? B GLN 599 NE2 
83  1 Y 1 B VAL 589 ? CG1 ? B VAL 600 CG1 
84  1 Y 1 B VAL 589 ? CG2 ? B VAL 600 CG2 
85  1 Y 1 B LYS 592 ? CG  ? B LYS 603 CG  
86  1 Y 1 B LYS 592 ? CD  ? B LYS 603 CD  
87  1 Y 1 B LYS 592 ? CE  ? B LYS 603 CE  
88  1 Y 1 B LYS 592 ? NZ  ? B LYS 603 NZ  
89  1 Y 1 B ASP 599 ? CG  ? B ASP 610 CG  
90  1 Y 1 B ASP 599 ? OD1 ? B ASP 610 OD1 
91  1 Y 1 B ASP 599 ? OD2 ? B ASP 610 OD2 
92  1 Y 1 B THR 600 ? OG1 ? B THR 611 OG1 
93  1 Y 1 B THR 600 ? CG2 ? B THR 611 CG2 
94  1 Y 1 B LYS 602 ? CG  ? B LYS 613 CG  
95  1 Y 1 B LYS 602 ? CD  ? B LYS 613 CD  
96  1 Y 1 B LYS 602 ? CE  ? B LYS 613 CE  
97  1 Y 1 B LYS 602 ? NZ  ? B LYS 613 NZ  
98  1 Y 1 B ASP 603 ? CG  ? B ASP 614 CG  
99  1 Y 1 B ASP 603 ? OD1 ? B ASP 614 OD1 
100 1 Y 1 B ASP 603 ? OD2 ? B ASP 614 OD2 
101 1 Y 1 B HIS 628 ? CG  ? B HIS 639 CG  
102 1 Y 1 B HIS 628 ? ND1 ? B HIS 639 ND1 
103 1 Y 1 B HIS 628 ? CD2 ? B HIS 639 CD2 
104 1 Y 1 B HIS 628 ? CE1 ? B HIS 639 CE1 
105 1 Y 1 B HIS 628 ? NE2 ? B HIS 639 NE2 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8X1T 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8X1T 
_struct.title                        'Cryo-EM structure of human DRA (SLC26A3) bound with sulfate' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8X1T 
_struct_keywords.text            'human DRA (SLC26A3), sulfate, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    S26A3_HUMAN 
_struct_ref.pdbx_db_accession          P40879 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSG
ISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLP
NNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDP
VSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRFKVAVVGD
MNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRS
AVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTI
VLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAV
GFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIE
VPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHI
LMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8X1T A 12 ? 775 ? P40879 1 ? 764 ? 1 764 
2 1 8X1T B 12 ? 775 ? P40879 1 ? 764 ? 1 764 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8X1T MET A 1  ? UNP P40879 ? ? 'initiating methionine' -10 1  
1 8X1T ASP A 2  ? UNP P40879 ? ? 'expression tag'        -9  2  
1 8X1T TYR A 3  ? UNP P40879 ? ? 'expression tag'        -8  3  
1 8X1T LYS A 4  ? UNP P40879 ? ? 'expression tag'        -7  4  
1 8X1T ASP A 5  ? UNP P40879 ? ? 'expression tag'        -6  5  
1 8X1T ASP A 6  ? UNP P40879 ? ? 'expression tag'        -5  6  
1 8X1T ASP A 7  ? UNP P40879 ? ? 'expression tag'        -4  7  
1 8X1T ASP A 8  ? UNP P40879 ? ? 'expression tag'        -3  8  
1 8X1T LYS A 9  ? UNP P40879 ? ? 'expression tag'        -2  9  
1 8X1T GLY A 10 ? UNP P40879 ? ? 'expression tag'        -1  10 
1 8X1T THR A 11 ? UNP P40879 ? ? 'expression tag'        0   11 
2 8X1T MET B 1  ? UNP P40879 ? ? 'initiating methionine' -10 12 
2 8X1T ASP B 2  ? UNP P40879 ? ? 'expression tag'        -9  13 
2 8X1T TYR B 3  ? UNP P40879 ? ? 'expression tag'        -8  14 
2 8X1T LYS B 4  ? UNP P40879 ? ? 'expression tag'        -7  15 
2 8X1T ASP B 5  ? UNP P40879 ? ? 'expression tag'        -6  16 
2 8X1T ASP B 6  ? UNP P40879 ? ? 'expression tag'        -5  17 
2 8X1T ASP B 7  ? UNP P40879 ? ? 'expression tag'        -4  18 
2 8X1T ASP B 8  ? UNP P40879 ? ? 'expression tag'        -3  19 
2 8X1T LYS B 9  ? UNP P40879 ? ? 'expression tag'        -2  20 
2 8X1T GLY B 10 ? UNP P40879 ? ? 'expression tag'        -1  21 
2 8X1T THR B 11 ? UNP P40879 ? ? 'expression tag'        0   22 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 28  ? HIS A 36  ? SER A 17  HIS A 25  1 ? 9  
HELX_P HELX_P2  AA2 THR A 45  ? CYS A 54  ? THR A 34  CYS A 43  1 ? 10 
HELX_P HELX_P3  AA3 SER A 57  ? PHE A 69  ? SER A 46  PHE A 58  1 ? 13 
HELX_P HELX_P4  AA4 PRO A 70  ? LEU A 75  ? PRO A 59  LEU A 64  1 ? 6  
HELX_P HELX_P5  AA5 ARG A 79  ? ASP A 110 ? ARG A 68  ASP A 99  1 ? 32 
HELX_P HELX_P6  AA6 PRO A 113 ? GLY A 131 ? PRO A 102 GLY A 120 1 ? 19 
HELX_P HELX_P7  AA7 PHE A 141 ? ALA A 159 ? PHE A 130 ALA A 148 1 ? 19 
HELX_P HELX_P8  AA8 LEU A 180 ? LEU A 207 ? LEU A 169 LEU A 196 1 ? 28 
HELX_P HELX_P9  AA9 PHE A 211 ? LEU A 216 ? PHE A 200 LEU A 205 5 ? 6  
HELX_P HELX_P10 AB1 SER A 217 ? GLN A 236 ? SER A 206 GLN A 225 1 ? 20 
HELX_P HELX_P11 AB2 GLN A 236 ? PHE A 241 ? GLN A 225 PHE A 230 1 ? 6  
HELX_P HELX_P12 AB3 VAL A 252 ? GLN A 264 ? VAL A 241 GLN A 253 1 ? 13 
HELX_P HELX_P13 AB4 ASN A 269 ? PHE A 293 ? ASN A 258 PHE A 282 1 ? 25 
HELX_P HELX_P14 AB5 PRO A 302 ? CYS A 318 ? PRO A 291 CYS A 307 1 ? 17 
HELX_P HELX_P15 AB6 ASP A 319 ? PHE A 324 ? ASP A 308 PHE A 313 1 ? 6  
HELX_P HELX_P16 AB7 ASP A 343 ? THR A 350 ? ASP A 332 THR A 339 1 ? 8  
HELX_P HELX_P17 AB8 THR A 350 ? ASP A 377 ? THR A 339 ASP A 366 1 ? 28 
HELX_P HELX_P18 AB9 ASP A 381 ? PHE A 399 ? ASP A 370 PHE A 388 1 ? 19 
HELX_P HELX_P19 AC1 ALA A 407 ? THR A 417 ? ALA A 396 THR A 406 1 ? 11 
HELX_P HELX_P20 AC2 GLN A 422 ? ALA A 438 ? GLN A 411 ALA A 427 1 ? 17 
HELX_P HELX_P21 AC3 ILE A 439 ? ALA A 444 ? ILE A 428 ALA A 433 5 ? 6  
HELX_P HELX_P22 AC4 GLN A 447 ? MET A 464 ? GLN A 436 MET A 453 1 ? 18 
HELX_P HELX_P23 AC5 ALA A 467 ? ASP A 476 ? ALA A 456 ASP A 465 1 ? 10 
HELX_P HELX_P24 AC6 ASP A 476 ? LEU A 493 ? ASP A 465 LEU A 482 1 ? 18 
HELX_P HELX_P25 AC7 LEU A 495 ? THR A 514 ? LEU A 484 THR A 503 1 ? 20 
HELX_P HELX_P26 AC8 ASN A 559 ? GLY A 572 ? ASN A 548 GLY A 561 1 ? 14 
HELX_P HELX_P27 AC9 SER A 574 ? GLN A 595 ? SER A 563 GLN A 584 1 ? 22 
HELX_P HELX_P28 AD1 GLN A 623 ? GLN A 629 ? GLN A 612 GLN A 618 5 ? 7  
HELX_P HELX_P29 AD2 ASP A 671 ? ILE A 688 ? ASP A 660 ILE A 677 1 ? 18 
HELX_P HELX_P30 AD3 ASP A 698 ? TYR A 708 ? ASP A 687 TYR A 697 1 ? 11 
HELX_P HELX_P31 AD4 LYS A 716 ? SER A 718 ? LYS A 705 SER A 707 5 ? 3  
HELX_P HELX_P32 AD5 THR A 723 ? ASP A 736 ? THR A 712 ASP A 725 1 ? 14 
HELX_P HELX_P33 AD6 SER B 28  ? HIS B 36  ? SER B 17  HIS B 25  1 ? 9  
HELX_P HELX_P34 AD7 THR B 45  ? CYS B 54  ? THR B 34  CYS B 43  1 ? 10 
HELX_P HELX_P35 AD8 SER B 57  ? PHE B 69  ? SER B 46  PHE B 58  1 ? 13 
HELX_P HELX_P36 AD9 PRO B 70  ? LEU B 75  ? PRO B 59  LEU B 64  1 ? 6  
HELX_P HELX_P37 AE1 ARG B 79  ? ASP B 110 ? ARG B 68  ASP B 99  1 ? 32 
HELX_P HELX_P38 AE2 PRO B 113 ? SER B 120 ? PRO B 102 SER B 109 1 ? 8  
HELX_P HELX_P39 AE3 PHE B 121 ? GLY B 131 ? PHE B 110 GLY B 120 1 ? 11 
HELX_P HELX_P40 AE4 PHE B 141 ? LYS B 158 ? PHE B 130 LYS B 147 1 ? 18 
HELX_P HELX_P41 AE5 ASP B 181 ? LEU B 207 ? ASP B 170 LEU B 196 1 ? 27 
HELX_P HELX_P42 AE6 PHE B 211 ? LEU B 216 ? PHE B 200 LEU B 205 5 ? 6  
HELX_P HELX_P43 AE7 SER B 217 ? GLN B 236 ? SER B 206 GLN B 225 1 ? 20 
HELX_P HELX_P44 AE8 GLN B 236 ? PHE B 241 ? GLN B 225 PHE B 230 1 ? 6  
HELX_P HELX_P45 AE9 VAL B 252 ? GLN B 264 ? VAL B 241 GLN B 253 1 ? 13 
HELX_P HELX_P46 AF1 ILE B 265 ? THR B 268 ? ILE B 254 THR B 257 5 ? 4  
HELX_P HELX_P47 AF2 ASN B 269 ? PHE B 293 ? ASN B 258 PHE B 282 1 ? 25 
HELX_P HELX_P48 AF3 PRO B 302 ? CYS B 318 ? PRO B 291 CYS B 307 1 ? 17 
HELX_P HELX_P49 AF4 ASP B 319 ? PHE B 324 ? ASP B 308 PHE B 313 1 ? 6  
HELX_P HELX_P50 AF5 ASP B 343 ? ASP B 377 ? ASP B 332 ASP B 366 1 ? 35 
HELX_P HELX_P51 AF6 ASP B 381 ? PHE B 399 ? ASP B 370 PHE B 388 1 ? 19 
HELX_P HELX_P52 AF7 ALA B 407 ? THR B 417 ? ALA B 396 THR B 406 1 ? 11 
HELX_P HELX_P53 AF8 GLN B 422 ? ALA B 438 ? GLN B 411 ALA B 427 1 ? 17 
HELX_P HELX_P54 AF9 ILE B 439 ? ALA B 444 ? ILE B 428 ALA B 433 5 ? 6  
HELX_P HELX_P55 AG1 GLN B 447 ? ASN B 458 ? GLN B 436 ASN B 447 1 ? 12 
HELX_P HELX_P56 AG2 LEU B 459 ? MET B 464 ? LEU B 448 MET B 453 1 ? 6  
HELX_P HELX_P57 AG3 ALA B 467 ? ASP B 476 ? ALA B 456 ASP B 465 1 ? 10 
HELX_P HELX_P58 AG4 ASP B 476 ? GLY B 494 ? ASP B 465 GLY B 483 1 ? 19 
HELX_P HELX_P59 AG5 GLY B 494 ? GLN B 515 ? GLY B 483 GLN B 504 1 ? 22 
HELX_P HELX_P60 AG6 ASN B 559 ? GLY B 572 ? ASN B 548 GLY B 561 1 ? 14 
HELX_P HELX_P61 AG7 SER B 574 ? GLY B 596 ? SER B 563 GLY B 585 1 ? 23 
HELX_P HELX_P62 AG8 GLN B 623 ? GLN B 629 ? GLN B 612 GLN B 618 5 ? 7  
HELX_P HELX_P63 AG9 LEU B 646 ? ILE B 650 ? LEU B 635 ILE B 639 5 ? 5  
HELX_P HELX_P64 AH1 ASP B 671 ? ILE B 688 ? ASP B 660 ILE B 677 1 ? 18 
HELX_P HELX_P65 AH2 ASP B 698 ? TYR B 708 ? ASP B 687 TYR B 697 1 ? 11 
HELX_P HELX_P66 AH3 LYS B 716 ? PHE B 720 ? LYS B 705 PHE B 709 5 ? 5  
HELX_P HELX_P67 AH4 THR B 723 ? ASP B 736 ? THR B 712 ASP B 725 1 ? 14 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ASP 250 A . ? ASP 239 A PRO 251 A ? PRO 240 A 1 12.22 
2 ASP 250 B . ? ASP 239 B PRO 251 B ? PRO 240 B 1 13.29 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 6 ? 
AA3 ? 2 ? 
AA4 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA2 5 6 ? parallel      
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 19  ? ARG A 24  ? GLN A 8   ARG A 13  
AA1 2 TYR B 20  ? PRO B 25  ? TYR B 9   PRO B 14  
AA2 1 TYR A 531 ? ASN A 533 ? TYR A 520 ASN A 522 
AA2 2 SER A 520 ? ASN A 524 ? SER A 509 ASN A 513 
AA2 3 VAL A 546 ? ARG A 550 ? VAL A 535 ARG A 539 
AA2 4 SER A 659 ? ASP A 663 ? SER A 648 ASP A 652 
AA2 5 ASP A 691 ? VAL A 695 ? ASP A 680 VAL A 684 
AA2 6 PHE A 720 ? PHE A 721 ? PHE A 709 PHE A 710 
AA3 1 GLN A 599 ? VAL A 600 ? GLN A 588 VAL A 589 
AA3 2 PHE A 605 ? ILE A 606 ? PHE A 594 ILE A 595 
AA4 1 TYR B 531 ? ASN B 533 ? TYR B 520 ASN B 522 
AA4 2 SER B 520 ? ASN B 524 ? SER B 509 ASN B 513 
AA4 3 VAL B 546 ? ARG B 550 ? VAL B 535 ARG B 539 
AA4 4 SER B 659 ? ASP B 663 ? SER B 648 ASP B 652 
AA4 5 ASP B 691 ? VAL B 695 ? ASP B 680 VAL B 684 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N TYR A 20  ? N TYR A 9   O ARG B 24  ? O ARG B 13  
AA2 1 2 O LYS A 532 ? O LYS A 521 N ALA A 523 ? N ALA A 512 
AA2 2 3 N SER A 520 ? N SER A 509 O ARG A 550 ? O ARG A 539 
AA2 3 4 N PHE A 549 ? N PHE A 538 O ASP A 663 ? O ASP A 652 
AA2 4 5 N LEU A 662 ? N LEU A 651 O TYR A 693 ? O TYR A 682 
AA2 5 6 N ILE A 694 ? N ILE A 683 O PHE A 721 ? O PHE A 710 
AA3 1 2 N GLN A 599 ? N GLN A 588 O ILE A 606 ? O ILE A 595 
AA4 1 2 O LYS B 532 ? O LYS B 521 N ALA B 523 ? N ALA B 512 
AA4 2 3 N LEU B 522 ? N LEU B 511 O ILE B 548 ? O ILE B 537 
AA4 3 4 N LYS B 547 ? N LYS B 536 O ILE B 661 ? O ILE B 650 
AA4 4 5 N LEU B 660 ? N LEU B 649 O ASP B 691 ? O ASP B 680 
# 
_pdbx_entry_details.entry_id                   8X1T 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 CYS A 45  ? ? 48.98   22.50   
2  1 GLN A 231 ? ? 63.08   60.74   
3  1 ASP A 366 ? ? 60.24   66.79   
4  1 PHE A 388 ? ? -96.48  32.77   
5  1 THR A 395 ? ? -175.48 145.56  
6  1 THR A 503 ? ? -97.66  32.81   
7  1 ARG A 516 ? ? 36.92   44.73   
8  1 PRO A 541 ? ? -90.71  43.15   
9  1 ASP A 701 ? ? -163.24 -162.52 
10 1 CYS B 43  ? ? -99.43  37.32   
11 1 LYS B 147 ? ? -95.30  41.42   
12 1 PHE B 282 ? ? -85.29  30.32   
13 1 PHE B 388 ? ? -97.47  32.65   
14 1 SER B 394 ? ? -108.75 -70.34  
15 1 THR B 410 ? ? -128.84 -168.18 
16 1 PRO B 541 ? ? -78.88  29.94   
17 1 GLU B 607 ? ? 53.83   71.11   
18 1 LYS B 678 ? ? 70.43   32.37   
19 1 ASP B 701 ? ? -160.97 -159.36 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8X1T 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8X1T 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.47 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               270996 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 DRA 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8X1T 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             900 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           130000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8X1T 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   281 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8X1T 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET -10 ? A MET 1   
2   1 Y 1 A ASP -9  ? A ASP 2   
3   1 Y 1 A TYR -8  ? A TYR 3   
4   1 Y 1 A LYS -7  ? A LYS 4   
5   1 Y 1 A ASP -6  ? A ASP 5   
6   1 Y 1 A ASP -5  ? A ASP 6   
7   1 Y 1 A ASP -4  ? A ASP 7   
8   1 Y 1 A ASP -3  ? A ASP 8   
9   1 Y 1 A LYS -2  ? A LYS 9   
10  1 Y 1 A GLY -1  ? A GLY 10  
11  1 Y 1 A THR 0   ? A THR 11  
12  1 Y 1 A MET 1   ? A MET 12  
13  1 Y 1 A ILE 2   ? A ILE 13  
14  1 Y 1 A GLU 3   ? A GLU 14  
15  1 Y 1 A PRO 4   ? A PRO 15  
16  1 Y 1 A PHE 5   ? A PHE 16  
17  1 Y 1 A GLY 6   ? A GLY 17  
18  1 Y 1 A ASP 151 ? A ASP 162 
19  1 Y 1 A ARG 152 ? A ARG 163 
20  1 Y 1 A ASN 153 ? A ASN 164 
21  1 Y 1 A ALA 154 ? A ALA 165 
22  1 Y 1 A THR 155 ? A THR 166 
23  1 Y 1 A THR 156 ? A THR 167 
24  1 Y 1 A LEU 157 ? A LEU 168 
25  1 Y 1 A GLY 158 ? A GLY 169 
26  1 Y 1 A LEU 159 ? A LEU 170 
27  1 Y 1 A PRO 160 ? A PRO 171 
28  1 Y 1 A ASN 161 ? A ASN 172 
29  1 Y 1 A ASN 162 ? A ASN 173 
30  1 Y 1 A SER 163 ? A SER 174 
31  1 Y 1 A ASN 164 ? A ASN 175 
32  1 Y 1 A ASN 165 ? A ASN 176 
33  1 Y 1 A SER 166 ? A SER 177 
34  1 Y 1 A SER 167 ? A SER 178 
35  1 Y 1 A TYR 726 ? A TYR 737 
36  1 Y 1 A SER 727 ? A SER 738 
37  1 Y 1 A THR 728 ? A THR 739 
38  1 Y 1 A SER 729 ? A SER 740 
39  1 Y 1 A LYS 730 ? A LYS 741 
40  1 Y 1 A PHE 731 ? A PHE 742 
41  1 Y 1 A ASN 732 ? A ASN 743 
42  1 Y 1 A PRO 733 ? A PRO 744 
43  1 Y 1 A SER 734 ? A SER 745 
44  1 Y 1 A GLN 735 ? A GLN 746 
45  1 Y 1 A GLU 736 ? A GLU 747 
46  1 Y 1 A LYS 737 ? A LYS 748 
47  1 Y 1 A ASP 738 ? A ASP 749 
48  1 Y 1 A GLY 739 ? A GLY 750 
49  1 Y 1 A LYS 740 ? A LYS 751 
50  1 Y 1 A ILE 741 ? A ILE 752 
51  1 Y 1 A ASP 742 ? A ASP 753 
52  1 Y 1 A PHE 743 ? A PHE 754 
53  1 Y 1 A THR 744 ? A THR 755 
54  1 Y 1 A ILE 745 ? A ILE 756 
55  1 Y 1 A ASN 746 ? A ASN 757 
56  1 Y 1 A THR 747 ? A THR 758 
57  1 Y 1 A ASN 748 ? A ASN 759 
58  1 Y 1 A GLY 749 ? A GLY 760 
59  1 Y 1 A GLY 750 ? A GLY 761 
60  1 Y 1 A LEU 751 ? A LEU 762 
61  1 Y 1 A ARG 752 ? A ARG 763 
62  1 Y 1 A ASN 753 ? A ASN 764 
63  1 Y 1 A ARG 754 ? A ARG 765 
64  1 Y 1 A VAL 755 ? A VAL 766 
65  1 Y 1 A TYR 756 ? A TYR 767 
66  1 Y 1 A GLU 757 ? A GLU 768 
67  1 Y 1 A VAL 758 ? A VAL 769 
68  1 Y 1 A PRO 759 ? A PRO 770 
69  1 Y 1 A VAL 760 ? A VAL 771 
70  1 Y 1 A GLU 761 ? A GLU 772 
71  1 Y 1 A THR 762 ? A THR 773 
72  1 Y 1 A LYS 763 ? A LYS 774 
73  1 Y 1 A PHE 764 ? A PHE 775 
74  1 Y 1 B MET -10 ? B MET 1   
75  1 Y 1 B ASP -9  ? B ASP 2   
76  1 Y 1 B TYR -8  ? B TYR 3   
77  1 Y 1 B LYS -7  ? B LYS 4   
78  1 Y 1 B ASP -6  ? B ASP 5   
79  1 Y 1 B ASP -5  ? B ASP 6   
80  1 Y 1 B ASP -4  ? B ASP 7   
81  1 Y 1 B ASP -3  ? B ASP 8   
82  1 Y 1 B LYS -2  ? B LYS 9   
83  1 Y 1 B GLY -1  ? B GLY 10  
84  1 Y 1 B THR 0   ? B THR 11  
85  1 Y 1 B MET 1   ? B MET 12  
86  1 Y 1 B ILE 2   ? B ILE 13  
87  1 Y 1 B GLU 3   ? B GLU 14  
88  1 Y 1 B PRO 4   ? B PRO 15  
89  1 Y 1 B PHE 5   ? B PHE 16  
90  1 Y 1 B GLY 6   ? B GLY 17  
91  1 Y 1 B ASP 151 ? B ASP 162 
92  1 Y 1 B ARG 152 ? B ARG 163 
93  1 Y 1 B ASN 153 ? B ASN 164 
94  1 Y 1 B ALA 154 ? B ALA 165 
95  1 Y 1 B THR 155 ? B THR 166 
96  1 Y 1 B THR 156 ? B THR 167 
97  1 Y 1 B LEU 157 ? B LEU 168 
98  1 Y 1 B GLY 158 ? B GLY 169 
99  1 Y 1 B LEU 159 ? B LEU 170 
100 1 Y 1 B PRO 160 ? B PRO 171 
101 1 Y 1 B ASN 161 ? B ASN 172 
102 1 Y 1 B ASN 162 ? B ASN 173 
103 1 Y 1 B SER 163 ? B SER 174 
104 1 Y 1 B ASN 164 ? B ASN 175 
105 1 Y 1 B ASN 165 ? B ASN 176 
106 1 Y 1 B SER 166 ? B SER 177 
107 1 Y 1 B SER 167 ? B SER 178 
108 1 Y 1 B LEU 168 ? B LEU 179 
109 1 Y 1 B TYR 726 ? B TYR 737 
110 1 Y 1 B SER 727 ? B SER 738 
111 1 Y 1 B THR 728 ? B THR 739 
112 1 Y 1 B SER 729 ? B SER 740 
113 1 Y 1 B LYS 730 ? B LYS 741 
114 1 Y 1 B PHE 731 ? B PHE 742 
115 1 Y 1 B ASN 732 ? B ASN 743 
116 1 Y 1 B PRO 733 ? B PRO 744 
117 1 Y 1 B SER 734 ? B SER 745 
118 1 Y 1 B GLN 735 ? B GLN 746 
119 1 Y 1 B GLU 736 ? B GLU 747 
120 1 Y 1 B LYS 737 ? B LYS 748 
121 1 Y 1 B ASP 738 ? B ASP 749 
122 1 Y 1 B GLY 739 ? B GLY 750 
123 1 Y 1 B LYS 740 ? B LYS 751 
124 1 Y 1 B ILE 741 ? B ILE 752 
125 1 Y 1 B ASP 742 ? B ASP 753 
126 1 Y 1 B PHE 743 ? B PHE 754 
127 1 Y 1 B THR 744 ? B THR 755 
128 1 Y 1 B ILE 745 ? B ILE 756 
129 1 Y 1 B ASN 746 ? B ASN 757 
130 1 Y 1 B THR 747 ? B THR 758 
131 1 Y 1 B ASN 748 ? B ASN 759 
132 1 Y 1 B GLY 749 ? B GLY 760 
133 1 Y 1 B GLY 750 ? B GLY 761 
134 1 Y 1 B LEU 751 ? B LEU 762 
135 1 Y 1 B ARG 752 ? B ARG 763 
136 1 Y 1 B ASN 753 ? B ASN 764 
137 1 Y 1 B ARG 754 ? B ARG 765 
138 1 Y 1 B VAL 755 ? B VAL 766 
139 1 Y 1 B TYR 756 ? B TYR 767 
140 1 Y 1 B GLU 757 ? B GLU 768 
141 1 Y 1 B VAL 758 ? B VAL 769 
142 1 Y 1 B PRO 759 ? B PRO 770 
143 1 Y 1 B VAL 760 ? B VAL 771 
144 1 Y 1 B GLU 761 ? B GLU 772 
145 1 Y 1 B THR 762 ? B THR 773 
146 1 Y 1 B LYS 763 ? B LYS 774 
147 1 Y 1 B PHE 764 ? B PHE 775 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
SO4 S    S N N 301 
SO4 O1   O N N 302 
SO4 O2   O N N 303 
SO4 O3   O N N 304 
SO4 O4   O N N 305 
THR N    N N N 306 
THR CA   C N S 307 
THR C    C N N 308 
THR O    O N N 309 
THR CB   C N R 310 
THR OG1  O N N 311 
THR CG2  C N N 312 
THR OXT  O N N 313 
THR H    H N N 314 
THR H2   H N N 315 
THR HA   H N N 316 
THR HB   H N N 317 
THR HG1  H N N 318 
THR HG21 H N N 319 
THR HG22 H N N 320 
THR HG23 H N N 321 
THR HXT  H N N 322 
TRP N    N N N 323 
TRP CA   C N S 324 
TRP C    C N N 325 
TRP O    O N N 326 
TRP CB   C N N 327 
TRP CG   C Y N 328 
TRP CD1  C Y N 329 
TRP CD2  C Y N 330 
TRP NE1  N Y N 331 
TRP CE2  C Y N 332 
TRP CE3  C Y N 333 
TRP CZ2  C Y N 334 
TRP CZ3  C Y N 335 
TRP CH2  C Y N 336 
TRP OXT  O N N 337 
TRP H    H N N 338 
TRP H2   H N N 339 
TRP HA   H N N 340 
TRP HB2  H N N 341 
TRP HB3  H N N 342 
TRP HD1  H N N 343 
TRP HE1  H N N 344 
TRP HE3  H N N 345 
TRP HZ2  H N N 346 
TRP HZ3  H N N 347 
TRP HH2  H N N 348 
TRP HXT  H N N 349 
TYR N    N N N 350 
TYR CA   C N S 351 
TYR C    C N N 352 
TYR O    O N N 353 
TYR CB   C N N 354 
TYR CG   C Y N 355 
TYR CD1  C Y N 356 
TYR CD2  C Y N 357 
TYR CE1  C Y N 358 
TYR CE2  C Y N 359 
TYR CZ   C Y N 360 
TYR OH   O N N 361 
TYR OXT  O N N 362 
TYR H    H N N 363 
TYR H2   H N N 364 
TYR HA   H N N 365 
TYR HB2  H N N 366 
TYR HB3  H N N 367 
TYR HD1  H N N 368 
TYR HD2  H N N 369 
TYR HE1  H N N 370 
TYR HE2  H N N 371 
TYR HH   H N N 372 
TYR HXT  H N N 373 
VAL N    N N N 374 
VAL CA   C N S 375 
VAL C    C N N 376 
VAL O    O N N 377 
VAL CB   C N N 378 
VAL CG1  C N N 379 
VAL CG2  C N N 380 
VAL OXT  O N N 381 
VAL H    H N N 382 
VAL H2   H N N 383 
VAL HA   H N N 384 
VAL HB   H N N 385 
VAL HG11 H N N 386 
VAL HG12 H N N 387 
VAL HG13 H N N 388 
VAL HG21 H N N 389 
VAL HG22 H N N 390 
VAL HG23 H N N 391 
VAL HXT  H N N 392 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
SO4 S   O1   doub N N 288 
SO4 S   O2   doub N N 289 
SO4 S   O3   sing N N 290 
SO4 S   O4   sing N N 291 
THR N   CA   sing N N 292 
THR N   H    sing N N 293 
THR N   H2   sing N N 294 
THR CA  C    sing N N 295 
THR CA  CB   sing N N 296 
THR CA  HA   sing N N 297 
THR C   O    doub N N 298 
THR C   OXT  sing N N 299 
THR CB  OG1  sing N N 300 
THR CB  CG2  sing N N 301 
THR CB  HB   sing N N 302 
THR OG1 HG1  sing N N 303 
THR CG2 HG21 sing N N 304 
THR CG2 HG22 sing N N 305 
THR CG2 HG23 sing N N 306 
THR OXT HXT  sing N N 307 
TRP N   CA   sing N N 308 
TRP N   H    sing N N 309 
TRP N   H2   sing N N 310 
TRP CA  C    sing N N 311 
TRP CA  CB   sing N N 312 
TRP CA  HA   sing N N 313 
TRP C   O    doub N N 314 
TRP C   OXT  sing N N 315 
TRP CB  CG   sing N N 316 
TRP CB  HB2  sing N N 317 
TRP CB  HB3  sing N N 318 
TRP CG  CD1  doub Y N 319 
TRP CG  CD2  sing Y N 320 
TRP CD1 NE1  sing Y N 321 
TRP CD1 HD1  sing N N 322 
TRP CD2 CE2  doub Y N 323 
TRP CD2 CE3  sing Y N 324 
TRP NE1 CE2  sing Y N 325 
TRP NE1 HE1  sing N N 326 
TRP CE2 CZ2  sing Y N 327 
TRP CE3 CZ3  doub Y N 328 
TRP CE3 HE3  sing N N 329 
TRP CZ2 CH2  doub Y N 330 
TRP CZ2 HZ2  sing N N 331 
TRP CZ3 CH2  sing Y N 332 
TRP CZ3 HZ3  sing N N 333 
TRP CH2 HH2  sing N N 334 
TRP OXT HXT  sing N N 335 
TYR N   CA   sing N N 336 
TYR N   H    sing N N 337 
TYR N   H2   sing N N 338 
TYR CA  C    sing N N 339 
TYR CA  CB   sing N N 340 
TYR CA  HA   sing N N 341 
TYR C   O    doub N N 342 
TYR C   OXT  sing N N 343 
TYR CB  CG   sing N N 344 
TYR CB  HB2  sing N N 345 
TYR CB  HB3  sing N N 346 
TYR CG  CD1  doub Y N 347 
TYR CG  CD2  sing Y N 348 
TYR CD1 CE1  sing Y N 349 
TYR CD1 HD1  sing N N 350 
TYR CD2 CE2  doub Y N 351 
TYR CD2 HD2  sing N N 352 
TYR CE1 CZ   doub Y N 353 
TYR CE1 HE1  sing N N 354 
TYR CE2 CZ   sing Y N 355 
TYR CE2 HE2  sing N N 356 
TYR CZ  OH   sing N N 357 
TYR OH  HH   sing N N 358 
TYR OXT HXT  sing N N 359 
VAL N   CA   sing N N 360 
VAL N   H    sing N N 361 
VAL N   H2   sing N N 362 
VAL CA  C    sing N N 363 
VAL CA  CB   sing N N 364 
VAL CA  HA   sing N N 365 
VAL C   O    doub N N 366 
VAL C   OXT  sing N N 367 
VAL CB  CG1  sing N N 368 
VAL CB  CG2  sing N N 369 
VAL CB  HB   sing N N 370 
VAL CG1 HG11 sing N N 371 
VAL CG1 HG12 sing N N 372 
VAL CG1 HG13 sing N N 373 
VAL CG2 HG21 sing N N 374 
VAL CG2 HG22 sing N N 375 
VAL CG2 HG23 sing N N 376 
VAL OXT HXT  sing N N 377 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-11-08 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8X1T 
_em_admin.last_update        2025-05-14 
_em_admin.map_release_date   2025-05-14 
_em_admin.title              'Cryo-EM structure of human DRA (SLC26A3) bound with sulfate' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               4.19 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         49.6 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'TFS FALCON 4i (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     3127 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'TFS Selectris X' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?   ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 EPU ? 
MASKING                         ? 3  ? ? ? ?   ? 
'CTF CORRECTION'                ? 4  1 ? ? ?   ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?   ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?   ? 
'MODEL FITTING'                 ? 7  ? ? ? ?   ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ?   ? 
OTHER                           ? 9  ? ? ? ?   ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?   ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?   ? 
CLASSIFICATION                  ? 12 1 ? ? ?   ? 
RECONSTRUCTION                  ? 13 1 ? ? ?   ? 
'VOLUME SELECTION'              ? 14 1 1 1 ?   ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ?   ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?   ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?   ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?   ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?   ? 
# 
_em_specimen.concentration           12 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8X1T 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . ASN A 1 18  ? 138.996 153.049 92.945  1.00 59.60  ?  7   ASN A N   1 
ATOM   2     C CA  . ASN A 1 18  ? 138.976 152.701 94.357  1.00 59.60  ?  7   ASN A CA  1 
ATOM   3     C C   . ASN A 1 18  ? 138.420 151.310 94.557  1.00 59.60  ?  7   ASN A C   1 
ATOM   4     O O   . ASN A 1 18  ? 137.454 151.123 95.297  1.00 59.60  ?  7   ASN A O   1 
ATOM   5     C CB  . ASN A 1 18  ? 138.149 153.719 95.148  1.00 59.60  ?  7   ASN A CB  1 
ATOM   6     C CG  . ASN A 1 18  ? 136.761 153.919 94.572  1.00 59.60  ?  7   ASN A CG  1 
ATOM   7     O OD1 . ASN A 1 18  ? 135.808 153.249 94.971  1.00 59.60  ?  7   ASN A OD1 1 
ATOM   8     N ND2 . ASN A 1 18  ? 136.638 154.847 93.631  1.00 59.60  ?  7   ASN A ND2 1 
ATOM   9     N N   . GLN A 1 19  ? 139.041 150.326 93.902  1.00 54.27  ?  8   GLN A N   1 
ATOM   10    C CA  . GLN A 1 19  ? 138.516 148.969 93.982  1.00 54.27  ?  8   GLN A CA  1 
ATOM   11    C C   . GLN A 1 19  ? 139.396 148.007 94.750  1.00 54.27  ?  8   GLN A C   1 
ATOM   12    O O   . GLN A 1 19  ? 140.613 148.019 94.614  1.00 54.27  ?  8   GLN A O   1 
ATOM   13    C CB  . GLN A 1 19  ? 138.242 148.414 92.581  1.00 54.27  ?  8   GLN A CB  1 
ATOM   14    C CG  . GLN A 1 19  ? 137.044 149.038 91.893  1.00 54.27  ?  8   GLN A CG  1 
ATOM   15    C CD  . GLN A 1 19  ? 135.729 148.572 92.483  1.00 54.27  ?  8   GLN A CD  1 
ATOM   16    O OE1 . GLN A 1 19  ? 134.953 149.371 93.006  1.00 54.27  ?  8   GLN A OE1 1 
ATOM   17    N NE2 . GLN A 1 19  ? 135.475 147.271 92.407  1.00 54.27  ?  8   GLN A NE2 1 
ATOM   18    N N   . TYR A 1 20  ? 138.765 147.185 95.582  1.00 46.87  ?  9   TYR A N   1 
ATOM   19    C CA  . TYR A 1 20  ? 139.483 146.172 96.318  1.00 46.87  ?  9   TYR A CA  1 
ATOM   20    C C   . TYR A 1 20  ? 139.507 144.964 95.415  1.00 46.87  ?  9   TYR A C   1 
ATOM   21    O O   . TYR A 1 20  ? 138.513 144.260 95.298  1.00 46.87  ?  9   TYR A O   1 
ATOM   22    C CB  . TYR A 1 20  ? 138.716 145.905 97.606  1.00 46.87  ?  9   TYR A CB  1 
ATOM   23    C CG  . TYR A 1 20  ? 139.219 144.849 98.554  1.00 46.87  ?  9   TYR A CG  1 
ATOM   24    C CD1 . TYR A 1 20  ? 139.738 145.201 99.791  1.00 46.87  ?  9   TYR A CD1 1 
ATOM   25    C CD2 . TYR A 1 20  ? 139.107 143.500 98.253  1.00 46.87  ?  9   TYR A CD2 1 
ATOM   26    C CE1 . TYR A 1 20  ? 140.170 144.244 100.682 1.00 46.87  ?  9   TYR A CE1 1 
ATOM   27    C CE2 . TYR A 1 20  ? 139.539 142.534 99.138  1.00 46.87  ?  9   TYR A CE2 1 
ATOM   28    C CZ  . TYR A 1 20  ? 140.068 142.913 100.350 1.00 46.87  ?  9   TYR A CZ  1 
ATOM   29    O OH  . TYR A 1 20  ? 140.499 141.958 101.236 1.00 46.87  ?  9   TYR A OH  1 
ATOM   30    N N   . ILE A 1 21  ? 140.622 144.738 94.738  1.00 48.86  ?  10  ILE A N   1 
ATOM   31    C CA  . ILE A 1 21  ? 140.717 143.617 93.805  1.00 48.86  ?  10  ILE A CA  1 
ATOM   32    C C   . ILE A 1 21  ? 141.731 142.600 94.280  1.00 48.86  ?  10  ILE A C   1 
ATOM   33    O O   . ILE A 1 21  ? 142.900 142.917 94.461  1.00 48.86  ?  10  ILE A O   1 
ATOM   34    C CB  . ILE A 1 21  ? 141.064 144.074 92.380  1.00 48.86  ?  10  ILE A CB  1 
ATOM   35    C CG1 . ILE A 1 21  ? 140.038 145.098 91.899  1.00 48.86  ?  10  ILE A CG1 1 
ATOM   36    C CG2 . ILE A 1 21  ? 141.118 142.883 91.438  1.00 48.86  ?  10  ILE A CG2 1 
ATOM   37    C CD1 . ILE A 1 21  ? 140.332 145.659 90.528  1.00 48.86  ?  10  ILE A CD1 1 
ATOM   38    N N   . VAL A 1 22  ? 141.288 141.375 94.479  1.00 47.74  ?  11  VAL A N   1 
ATOM   39    C CA  . VAL A 1 22  ? 142.164 140.339 94.994  1.00 47.74  ?  11  VAL A CA  1 
ATOM   40    C C   . VAL A 1 22  ? 141.970 139.082 94.162  1.00 47.74  ?  11  VAL A C   1 
ATOM   41    O O   . VAL A 1 22  ? 140.871 138.814 93.731  1.00 47.74  ?  11  VAL A O   1 
ATOM   42    C CB  . VAL A 1 22  ? 141.825 140.092 96.479  1.00 47.74  ?  11  VAL A CB  1 
ATOM   43    C CG1 . VAL A 1 22  ? 142.452 138.828 97.030  1.00 47.74  ?  11  VAL A CG1 1 
ATOM   44    C CG2 . VAL A 1 22  ? 142.253 141.279 97.309  1.00 47.74  ?  11  VAL A CG2 1 
ATOM   45    N N   . ALA A 1 23  ? 143.043 138.350 93.888  1.00 49.39  ?  12  ALA A N   1 
ATOM   46    C CA  . ALA A 1 23  ? 142.983 137.101 93.145  1.00 49.39  ?  12  ALA A CA  1 
ATOM   47    C C   . ALA A 1 23  ? 144.124 136.245 93.666  1.00 49.39  ?  12  ALA A C   1 
ATOM   48    O O   . ALA A 1 23  ? 145.222 136.287 93.135  1.00 49.39  ?  12  ALA A O   1 
ATOM   49    C CB  . ALA A 1 23  ? 143.134 137.353 91.663  1.00 49.39  ?  12  ALA A CB  1 
ATOM   50    N N   . ARG A 1 24  ? 143.856 135.467 94.708  1.00 49.13  ?  13  ARG A N   1 
ATOM   51    C CA  . ARG A 1 24  ? 144.863 134.642 95.356  1.00 49.13  ?  13  ARG A CA  1 
ATOM   52    C C   . ARG A 1 24  ? 144.284 133.255 95.597  1.00 49.13  ?  13  ARG A C   1 
ATOM   53    O O   . ARG A 1 24  ? 143.070 133.069 95.457  1.00 49.13  ?  13  ARG A O   1 
ATOM   54    C CB  . ARG A 1 24  ? 145.321 135.290 96.664  1.00 49.13  ?  13  ARG A CB  1 
ATOM   55    C CG  . ARG A 1 24  ? 144.255 135.442 97.731  1.00 49.13  ?  13  ARG A CG  1 
ATOM   56    C CD  . ARG A 1 24  ? 144.908 135.766 99.052  1.00 49.13  ?  13  ARG A CD  1 
ATOM   57    N NE  . ARG A 1 24  ? 143.974 136.086 100.122 1.00 49.13  ?  13  ARG A NE  1 
ATOM   58    C CZ  . ARG A 1 24  ? 143.393 135.182 100.898 1.00 49.13  ?  13  ARG A CZ  1 
ATOM   59    N NH1 . ARG A 1 24  ? 143.633 133.896 100.709 1.00 49.13  1  13  ARG A NH1 1 
ATOM   60    N NH2 . ARG A 1 24  ? 142.570 135.560 101.859 1.00 49.13  ?  13  ARG A NH2 1 
ATOM   61    N N   . PRO A 1 25  ? 145.095 132.255 95.928  1.00 52.21  ?  14  PRO A N   1 
ATOM   62    C CA  . PRO A 1 25  ? 144.538 130.933 96.220  1.00 52.21  ?  14  PRO A CA  1 
ATOM   63    C C   . PRO A 1 25  ? 143.929 130.874 97.612  1.00 52.21  ?  14  PRO A C   1 
ATOM   64    O O   . PRO A 1 25  ? 144.262 131.653 98.504  1.00 52.21  ?  14  PRO A O   1 
ATOM   65    C CB  . PRO A 1 25  ? 145.747 130.004 96.104  1.00 52.21  ?  14  PRO A CB  1 
ATOM   66    C CG  . PRO A 1 25  ? 146.902 130.866 96.375  1.00 52.21  ?  14  PRO A CG  1 
ATOM   67    C CD  . PRO A 1 25  ? 146.562 132.212 95.824  1.00 52.21  ?  14  PRO A CD  1 
ATOM   68    N N   . VAL A 1 26  ? 143.022 129.926 97.822  1.00 52.49  ?  15  VAL A N   1 
ATOM   69    C CA  . VAL A 1 26  ? 142.411 129.748 99.138  1.00 52.49  ?  15  VAL A CA  1 
ATOM   70    C C   . VAL A 1 26  ? 143.426 129.149 100.089 1.00 52.49  ?  15  VAL A C   1 
ATOM   71    O O   . VAL A 1 26  ? 144.169 128.250 99.714  1.00 52.49  ?  15  VAL A O   1 
ATOM   72    C CB  . VAL A 1 26  ? 141.162 128.852 99.064  1.00 52.49  ?  15  VAL A CB  1 
ATOM   73    C CG1 . VAL A 1 26  ? 140.625 128.554 100.454 1.00 52.49  ?  15  VAL A CG1 1 
ATOM   74    C CG2 . VAL A 1 26  ? 140.098 129.503 98.196  1.00 52.49  ?  15  VAL A CG2 1 
ATOM   75    N N   . TYR A 1 27  ? 143.462 129.619 101.325 1.00 51.92  ?  16  TYR A N   1 
ATOM   76    C CA  . TYR A 1 27  ? 144.503 129.156 102.235 1.00 51.92  ?  16  TYR A CA  1 
ATOM   77    C C   . TYR A 1 27  ? 144.107 128.633 103.587 1.00 51.92  ?  16  TYR A C   1 
ATOM   78    O O   . TYR A 1 27  ? 143.424 129.318 104.340 1.00 51.92  ?  16  TYR A O   1 
ATOM   79    C CB  . TYR A 1 27  ? 145.480 130.303 102.527 1.00 51.92  ?  16  TYR A CB  1 
ATOM   80    C CG  . TYR A 1 27  ? 146.539 130.553 101.491 1.00 51.92  ?  16  TYR A CG  1 
ATOM   81    C CD1 . TYR A 1 27  ? 147.497 129.594 101.204 1.00 51.92  ?  16  TYR A CD1 1 
ATOM   82    C CD2 . TYR A 1 27  ? 146.609 131.769 100.831 1.00 51.92  ?  16  TYR A CD2 1 
ATOM   83    C CE1 . TYR A 1 27  ? 148.480 129.829 100.265 1.00 51.92  ?  16  TYR A CE1 1 
ATOM   84    C CE2 . TYR A 1 27  ? 147.588 132.014 99.893  1.00 51.92  ?  16  TYR A CE2 1 
ATOM   85    C CZ  . TYR A 1 27  ? 148.520 131.041 99.615  1.00 51.92  ?  16  TYR A CZ  1 
ATOM   86    O OH  . TYR A 1 27  ? 149.494 131.284 98.679  1.00 51.92  ?  16  TYR A OH  1 
ATOM   87    N N   . SER A 1 28  ? 144.541 127.426 103.910 1.00 51.80  ?  17  SER A N   1 
ATOM   88    C CA  . SER A 1 28  ? 144.355 126.935 105.249 1.00 51.80  ?  17  SER A CA  1 
ATOM   89    C C   . SER A 1 28  ? 145.558 127.555 105.921 1.00 51.80  ?  17  SER A C   1 
ATOM   90    O O   . SER A 1 28  ? 146.480 128.002 105.248 1.00 51.80  ?  17  SER A O   1 
ATOM   91    C CB  . SER A 1 28  ? 144.424 125.426 105.301 1.00 51.80  ?  17  SER A CB  1 
ATOM   92    O OG  . SER A 1 28  ? 144.297 124.959 106.630 1.00 51.80  ?  17  SER A OG  1 
ATOM   93    N N   . THR A 1 29  ? 145.576 127.603 107.239 1.00 54.40  ?  18  THR A N   1 
ATOM   94    C CA  . THR A 1 29  ? 146.735 128.131 107.932 1.00 54.40  ?  18  THR A CA  1 
ATOM   95    C C   . THR A 1 29  ? 147.948 127.291 107.579 1.00 54.40  ?  18  THR A C   1 
ATOM   96    O O   . THR A 1 29  ? 149.040 127.817 107.421 1.00 54.40  ?  18  THR A O   1 
ATOM   97    C CB  . THR A 1 29  ? 146.519 128.161 109.450 1.00 54.40  ?  18  THR A CB  1 
ATOM   98    O OG1 . THR A 1 29  ? 145.350 128.932 109.749 1.00 54.40  ?  18  THR A OG1 1 
ATOM   99    C CG2 . THR A 1 29  ? 147.716 128.781 110.141 1.00 54.40  ?  18  THR A CG2 1 
ATOM   100   N N   . ASN A 1 30  ? 147.754 125.988 107.433 1.00 57.08  ?  19  ASN A N   1 
ATOM   101   C CA  . ASN A 1 30  ? 148.841 125.085 107.077 1.00 57.08  ?  19  ASN A CA  1 
ATOM   102   C C   . ASN A 1 30  ? 149.340 125.277 105.646 1.00 57.08  ?  19  ASN A C   1 
ATOM   103   O O   . ASN A 1 30  ? 150.546 125.284 105.424 1.00 57.08  ?  19  ASN A O   1 
ATOM   104   C CB  . ASN A 1 30  ? 148.393 123.639 107.293 1.00 57.08  ?  19  ASN A CB  1 
ATOM   105   C CG  . ASN A 1 30  ? 148.174 123.308 108.754 1.00 57.08  ?  19  ASN A CG  1 
ATOM   106   O OD1 . ASN A 1 30  ? 148.527 124.085 109.639 1.00 57.08  ?  19  ASN A OD1 1 
ATOM   107   N ND2 . ASN A 1 30  ? 147.592 122.146 109.015 1.00 57.08  ?  19  ASN A ND2 1 
ATOM   108   N N   . ALA A 1 31  ? 148.442 125.430 104.674 1.00 57.17  ?  20  ALA A N   1 
ATOM   109   C CA  . ALA A 1 31  ? 148.872 125.705 103.311 1.00 57.17  ?  20  ALA A CA  1 
ATOM   110   C C   . ALA A 1 31  ? 149.636 127.016 103.208 1.00 57.17  ?  20  ALA A C   1 
ATOM   111   O O   . ALA A 1 31  ? 150.564 127.118 102.397 1.00 57.17  ?  20  ALA A O   1 
ATOM   112   C CB  . ALA A 1 31  ? 147.671 125.729 102.371 1.00 57.17  ?  20  ALA A CB  1 
ATOM   113   N N   . PHE A 1 32  ? 149.277 128.012 104.015 1.00 56.45  ?  21  PHE A N   1 
ATOM   114   C CA  . PHE A 1 32  ? 150.022 129.262 104.018 1.00 56.45  ?  21  PHE A CA  1 
ATOM   115   C C   . PHE A 1 32  ? 151.418 129.076 104.596 1.00 56.45  ?  21  PHE A C   1 
ATOM   116   O O   . PHE A 1 32  ? 152.386 129.631 104.065 1.00 56.45  ?  21  PHE A O   1 
ATOM   117   C CB  . PHE A 1 32  ? 149.253 130.327 104.797 1.00 56.45  ?  21  PHE A CB  1 
ATOM   118   C CG  . PHE A 1 32  ? 149.802 131.709 104.629 1.00 56.45  ?  21  PHE A CG  1 
ATOM   119   C CD1 . PHE A 1 32  ? 149.616 132.403 103.453 1.00 56.45  ?  21  PHE A CD1 1 
ATOM   120   C CD2 . PHE A 1 32  ? 150.509 132.312 105.648 1.00 56.45  ?  21  PHE A CD2 1 
ATOM   121   C CE1 . PHE A 1 32  ? 150.123 133.666 103.298 1.00 56.45  ?  21  PHE A CE1 1 
ATOM   122   C CE2 . PHE A 1 32  ? 151.018 133.575 105.494 1.00 56.45  ?  21  PHE A CE2 1 
ATOM   123   C CZ  . PHE A 1 32  ? 150.826 134.251 104.318 1.00 56.45  ?  21  PHE A CZ  1 
ATOM   124   N N   . GLU A 1 33  ? 151.551 128.304 105.677 1.00 60.64  ?  22  GLU A N   1 
ATOM   125   C CA  . GLU A 1 33  ? 152.883 128.023 106.205 1.00 60.64  ?  22  GLU A CA  1 
ATOM   126   C C   . GLU A 1 33  ? 153.717 127.213 105.224 1.00 60.64  ?  22  GLU A C   1 
ATOM   127   O O   . GLU A 1 33  ? 154.935 127.401 105.149 1.00 60.64  ?  22  GLU A O   1 
ATOM   128   C CB  . GLU A 1 33  ? 152.802 127.281 107.538 1.00 60.64  ?  22  GLU A CB  1 
ATOM   129   C CG  . GLU A 1 33  ? 151.824 127.848 108.542 1.00 60.64  ?  22  GLU A CG  1 
ATOM   130   C CD  . GLU A 1 33  ? 151.973 129.337 108.739 1.00 60.64  ?  22  GLU A CD  1 
ATOM   131   O OE1 . GLU A 1 33  ? 153.122 129.809 108.857 1.00 60.64  ?  22  GLU A OE1 1 
ATOM   132   O OE2 . GLU A 1 33  ? 150.940 130.037 108.781 1.00 60.64  -1 22  GLU A OE2 1 
ATOM   133   N N   . GLU A 1 34  ? 153.092 126.307 104.472 1.00 63.04  ?  23  GLU A N   1 
ATOM   134   C CA  . GLU A 1 34  ? 153.844 125.532 103.491 1.00 63.04  ?  23  GLU A CA  1 
ATOM   135   C C   . GLU A 1 34  ? 154.311 126.404 102.334 1.00 63.04  ?  23  GLU A C   1 
ATOM   136   O O   . GLU A 1 34  ? 155.457 126.289 101.887 1.00 63.04  ?  23  GLU A O   1 
ATOM   137   C CB  . GLU A 1 34  ? 153.005 124.368 102.968 1.00 63.04  ?  23  GLU A CB  1 
ATOM   138   C CG  . GLU A 1 34  ? 152.758 123.260 103.973 1.00 63.04  ?  23  GLU A CG  1 
ATOM   139   C CD  . GLU A 1 34  ? 151.518 122.453 103.651 1.00 63.04  ?  23  GLU A CD  1 
ATOM   140   O OE1 . GLU A 1 34  ? 150.998 121.765 104.556 1.00 63.04  ?  23  GLU A OE1 1 
ATOM   141   O OE2 . GLU A 1 34  ? 151.061 122.507 102.491 1.00 63.04  -1 23  GLU A OE2 1 
ATOM   142   N N   . ASN A 1 35  ? 153.439 127.284 101.836 1.00 62.11  ?  24  ASN A N   1 
ATOM   143   C CA  . ASN A 1 35  ? 153.774 128.057 100.644 1.00 62.11  ?  24  ASN A CA  1 
ATOM   144   C C   . ASN A 1 35  ? 154.730 129.203 100.952 1.00 62.11  ?  24  ASN A C   1 
ATOM   145   O O   . ASN A 1 35  ? 155.512 129.609 100.085 1.00 62.11  ?  24  ASN A O   1 
ATOM   146   C CB  . ASN A 1 35  ? 152.499 128.590 99.997  1.00 62.11  ?  24  ASN A CB  1 
ATOM   147   C CG  . ASN A 1 35  ? 152.019 127.719 98.861  1.00 62.11  ?  24  ASN A CG  1 
ATOM   148   O OD1 . ASN A 1 35  ? 152.015 128.136 97.705  1.00 62.11  ?  24  ASN A OD1 1 
ATOM   149   N ND2 . ASN A 1 35  ? 151.614 126.498 99.183  1.00 62.11  ?  24  ASN A ND2 1 
ATOM   150   N N   . HIS A 1 36  ? 154.680 129.741 102.164 1.00 61.78  ?  25  HIS A N   1 
ATOM   151   C CA  . HIS A 1 36  ? 155.500 130.880 102.547 1.00 61.78  ?  25  HIS A CA  1 
ATOM   152   C C   . HIS A 1 36  ? 156.416 130.494 103.699 1.00 61.78  ?  25  HIS A C   1 
ATOM   153   O O   . HIS A 1 36  ? 155.975 130.392 104.846 1.00 61.78  ?  25  HIS A O   1 
ATOM   154   C CB  . HIS A 1 36  ? 154.624 132.065 102.953 1.00 61.78  ?  25  HIS A CB  1 
ATOM   155   C CG  . HIS A 1 36  ? 153.777 132.591 101.839 1.00 61.78  ?  25  HIS A CG  1 
ATOM   156   N ND1 . HIS A 1 36  ? 152.534 132.077 101.545 1.00 61.78  ?  25  HIS A ND1 1 
ATOM   157   C CD2 . HIS A 1 36  ? 154.002 133.572 100.937 1.00 61.78  ?  25  HIS A CD2 1 
ATOM   158   C CE1 . HIS A 1 36  ? 152.027 132.726 100.512 1.00 61.78  ?  25  HIS A CE1 1 
ATOM   159   N NE2 . HIS A 1 36  ? 152.898 133.638 100.124 1.00 61.78  ?  25  HIS A NE2 1 
ATOM   160   N N   . LYS A 1 37  ? 157.694 130.289 103.386 1.00 67.69  ?  26  LYS A N   1 
ATOM   161   C CA  . LYS A 1 37  ? 158.623 129.787 104.383 1.00 67.69  ?  26  LYS A CA  1 
ATOM   162   C C   . LYS A 1 37  ? 158.790 130.804 105.514 1.00 67.69  ?  26  LYS A C   1 
ATOM   163   O O   . LYS A 1 37  ? 158.902 132.013 105.304 1.00 67.69  ?  26  LYS A O   1 
ATOM   164   C CB  . LYS A 1 37  ? 159.963 129.434 103.738 1.00 67.69  ?  26  LYS A CB  1 
ATOM   165   N N   . LYS A 1 38  ? 158.794 130.283 106.738 1.00 67.21  ?  27  LYS A N   1 
ATOM   166   C CA  . LYS A 1 38  ? 158.659 131.092 107.941 1.00 67.21  ?  27  LYS A CA  1 
ATOM   167   C C   . LYS A 1 38  ? 160.041 131.398 108.491 1.00 67.21  ?  27  LYS A C   1 
ATOM   168   O O   . LYS A 1 38  ? 160.884 130.502 108.586 1.00 67.21  ?  27  LYS A O   1 
ATOM   169   C CB  . LYS A 1 38  ? 157.805 130.357 108.978 1.00 67.21  ?  27  LYS A CB  1 
ATOM   170   C CG  . LYS A 1 38  ? 157.316 131.204 110.131 1.00 67.21  ?  27  LYS A CG  1 
ATOM   171   C CD  . LYS A 1 38  ? 155.937 130.757 110.578 1.00 67.21  ?  27  LYS A CD  1 
ATOM   172   C CE  . LYS A 1 38  ? 155.448 131.572 111.760 1.00 67.21  ?  27  LYS A CE  1 
ATOM   173   N NZ  . LYS A 1 38  ? 154.065 131.198 112.149 1.00 67.21  1  27  LYS A NZ  1 
ATOM   174   N N   . THR A 1 39  ? 160.270 132.658 108.856 1.00 71.07  ?  28  THR A N   1 
ATOM   175   C CA  . THR A 1 39  ? 161.552 133.090 109.400 1.00 71.07  ?  28  THR A CA  1 
ATOM   176   C C   . THR A 1 39  ? 161.829 132.425 110.740 1.00 71.07  ?  28  THR A C   1 
ATOM   177   O O   . THR A 1 39  ? 161.130 132.682 111.724 1.00 71.07  ?  28  THR A O   1 
ATOM   178   C CB  . THR A 1 39  ? 161.583 134.610 109.559 1.00 71.07  ?  28  THR A CB  1 
ATOM   179   O OG1 . THR A 1 39  ? 161.587 135.226 108.266 1.00 71.07  ?  28  THR A OG1 1 
ATOM   180   C CG2 . THR A 1 39  ? 162.823 135.035 110.310 1.00 71.07  ?  28  THR A CG2 1 
ATOM   181   N N   . GLY A 1 40  ? 162.841 131.563 110.784 1.00 78.52  ?  29  GLY A N   1 
ATOM   182   C CA  . GLY A 1 40  ? 163.176 130.906 112.034 1.00 78.52  ?  29  GLY A CA  1 
ATOM   183   C C   . GLY A 1 40  ? 163.714 131.895 113.051 1.00 78.52  ?  29  GLY A C   1 
ATOM   184   O O   . GLY A 1 40  ? 164.647 132.655 112.777 1.00 78.52  ?  29  GLY A O   1 
ATOM   185   N N   . ARG A 1 41  ? 163.118 131.884 114.240 1.00 86.53  ?  30  ARG A N   1 
ATOM   186   C CA  . ARG A 1 41  ? 163.525 132.760 115.326 1.00 86.53  ?  30  ARG A CA  1 
ATOM   187   C C   . ARG A 1 41  ? 163.910 131.925 116.538 1.00 86.53  ?  30  ARG A C   1 
ATOM   188   O O   . ARG A 1 41  ? 163.283 130.904 116.835 1.00 86.53  ?  30  ARG A O   1 
ATOM   189   C CB  . ARG A 1 41  ? 162.416 133.758 115.694 1.00 86.53  ?  30  ARG A CB  1 
ATOM   190   C CG  . ARG A 1 41  ? 162.141 134.792 114.607 1.00 86.53  ?  30  ARG A CG  1 
ATOM   191   C CD  . ARG A 1 41  ? 160.762 135.420 114.742 1.00 86.53  ?  30  ARG A CD  1 
ATOM   192   N NE  . ARG A 1 41  ? 160.517 135.934 116.085 1.00 86.53  ?  30  ARG A NE  1 
ATOM   193   C CZ  . ARG A 1 41  ? 159.311 136.216 116.565 1.00 86.53  ?  30  ARG A CZ  1 
ATOM   194   N NH1 . ARG A 1 41  ? 159.180 136.679 117.800 1.00 86.53  1  30  ARG A NH1 1 
ATOM   195   N NH2 . ARG A 1 41  ? 158.234 136.035 115.812 1.00 86.53  ?  30  ARG A NH2 1 
ATOM   196   N N   . HIS A 1 42  ? 164.952 132.372 117.231 1.00 107.10 ?  31  HIS A N   1 
ATOM   197   C CA  . HIS A 1 42  ? 165.465 131.649 118.385 1.00 107.10 ?  31  HIS A CA  1 
ATOM   198   C C   . HIS A 1 42  ? 164.467 131.683 119.538 1.00 107.10 ?  31  HIS A C   1 
ATOM   199   O O   . HIS A 1 42  ? 163.526 132.482 119.554 1.00 107.10 ?  31  HIS A O   1 
ATOM   200   C CB  . HIS A 1 42  ? 166.798 132.247 118.837 1.00 107.10 ?  31  HIS A CB  1 
ATOM   201   C CG  . HIS A 1 42  ? 167.423 131.533 119.996 1.00 107.10 ?  31  HIS A CG  1 
ATOM   202   N ND1 . HIS A 1 42  ? 167.813 130.212 119.935 1.00 107.10 ?  31  HIS A ND1 1 
ATOM   203   C CD2 . HIS A 1 42  ? 167.721 131.956 121.247 1.00 107.10 ?  31  HIS A CD2 1 
ATOM   204   C CE1 . HIS A 1 42  ? 168.326 129.852 121.097 1.00 107.10 ?  31  HIS A CE1 1 
ATOM   205   N NE2 . HIS A 1 42  ? 168.282 130.892 121.911 1.00 107.10 ?  31  HIS A NE2 1 
ATOM   206   N N   . HIS A 1 43  ? 164.683 130.797 120.505 1.00 117.51 ?  32  HIS A N   1 
ATOM   207   C CA  . HIS A 1 43  ? 163.863 130.756 121.707 1.00 117.51 ?  32  HIS A CA  1 
ATOM   208   C C   . HIS A 1 43  ? 164.408 131.739 122.736 1.00 117.51 ?  32  HIS A C   1 
ATOM   209   O O   . HIS A 1 43  ? 165.597 131.708 123.066 1.00 117.51 ?  32  HIS A O   1 
ATOM   210   C CB  . HIS A 1 43  ? 163.846 129.345 122.290 1.00 117.51 ?  32  HIS A CB  1 
ATOM   211   C CG  . HIS A 1 43  ? 163.420 128.293 121.316 1.00 117.51 ?  32  HIS A CG  1 
ATOM   212   N ND1 . HIS A 1 43  ? 164.302 127.677 120.454 1.00 117.51 ?  32  HIS A ND1 1 
ATOM   213   C CD2 . HIS A 1 43  ? 162.206 127.747 121.063 1.00 117.51 ?  32  HIS A CD2 1 
ATOM   214   C CE1 . HIS A 1 43  ? 163.651 126.798 119.713 1.00 117.51 ?  32  HIS A CE1 1 
ATOM   215   N NE2 . HIS A 1 43  ? 162.377 126.820 120.064 1.00 117.51 ?  32  HIS A NE2 1 
ATOM   216   N N   . LYS A 1 44  ? 163.539 132.617 123.238 1.00 125.22 ?  33  LYS A N   1 
ATOM   217   C CA  . LYS A 1 44  ? 163.909 133.524 124.324 1.00 125.22 ?  33  LYS A CA  1 
ATOM   218   C C   . LYS A 1 44  ? 163.798 132.761 125.646 1.00 125.22 ?  33  LYS A C   1 
ATOM   219   O O   . LYS A 1 44  ? 162.884 132.952 126.452 1.00 125.22 ?  33  LYS A O   1 
ATOM   220   C CB  . LYS A 1 44  ? 163.034 134.771 124.308 1.00 125.22 ?  33  LYS A CB  1 
ATOM   221   N N   . THR A 1 45  ? 164.769 131.875 125.854 1.00 130.07 ?  34  THR A N   1 
ATOM   222   C CA  . THR A 1 45  ? 164.720 130.944 126.973 1.00 130.07 ?  34  THR A CA  1 
ATOM   223   C C   . THR A 1 45  ? 164.902 131.672 128.298 1.00 130.07 ?  34  THR A C   1 
ATOM   224   O O   . THR A 1 45  ? 165.612 132.678 128.385 1.00 130.07 ?  34  THR A O   1 
ATOM   225   C CB  . THR A 1 45  ? 165.798 129.871 126.808 1.00 130.07 ?  34  THR A CB  1 
ATOM   226   O OG1 . THR A 1 45  ? 165.807 129.406 125.453 1.00 130.07 ?  34  THR A OG1 1 
ATOM   227   C CG2 . THR A 1 45  ? 165.535 128.693 127.735 1.00 130.07 ?  34  THR A CG2 1 
ATOM   228   N N   . PHE A 1 46  ? 164.241 131.153 129.335 1.00 133.21 ?  35  PHE A N   1 
ATOM   229   C CA  . PHE A 1 46  ? 164.402 131.700 130.679 1.00 133.21 ?  35  PHE A CA  1 
ATOM   230   C C   . PHE A 1 46  ? 165.836 131.557 131.172 1.00 133.21 ?  35  PHE A C   1 
ATOM   231   O O   . PHE A 1 46  ? 166.312 132.396 131.943 1.00 133.21 ?  35  PHE A O   1 
ATOM   232   C CB  . PHE A 1 46  ? 163.431 131.003 131.633 1.00 133.21 ?  35  PHE A CB  1 
ATOM   233   C CG  . PHE A 1 46  ? 163.040 131.832 132.824 1.00 133.21 ?  35  PHE A CG  1 
ATOM   234   C CD1 . PHE A 1 46  ? 162.231 132.947 132.674 1.00 133.21 ?  35  PHE A CD1 1 
ATOM   235   C CD2 . PHE A 1 46  ? 163.460 131.481 134.096 1.00 133.21 ?  35  PHE A CD2 1 
ATOM   236   C CE1 . PHE A 1 46  ? 161.863 133.708 133.770 1.00 133.21 ?  35  PHE A CE1 1 
ATOM   237   C CE2 . PHE A 1 46  ? 163.095 132.235 135.194 1.00 133.21 ?  35  PHE A CE2 1 
ATOM   238   C CZ  . PHE A 1 46  ? 162.296 133.350 135.030 1.00 133.21 ?  35  PHE A CZ  1 
ATOM   239   N N   . LEU A 1 47  ? 166.548 130.520 130.724 1.00 132.68 ?  36  LEU A N   1 
ATOM   240   C CA  . LEU A 1 47  ? 167.908 130.299 131.204 1.00 132.68 ?  36  LEU A CA  1 
ATOM   241   C C   . LEU A 1 47  ? 168.874 131.317 130.606 1.00 132.68 ?  36  LEU A C   1 
ATOM   242   O O   . LEU A 1 47  ? 169.701 131.895 131.319 1.00 132.68 ?  36  LEU A O   1 
ATOM   243   C CB  . LEU A 1 47  ? 168.351 128.868 130.886 1.00 132.68 ?  36  LEU A CB  1 
ATOM   244   N N   . ASP A 1 48  ? 168.787 131.554 129.296 1.00 133.20 ?  37  ASP A N   1 
ATOM   245   C CA  . ASP A 1 48  ? 169.656 132.556 128.688 1.00 133.20 ?  37  ASP A CA  1 
ATOM   246   C C   . ASP A 1 48  ? 169.272 133.958 129.147 1.00 133.20 ?  37  ASP A C   1 
ATOM   247   O O   . ASP A 1 48  ? 170.126 134.850 129.235 1.00 133.20 ?  37  ASP A O   1 
ATOM   248   C CB  . ASP A 1 48  ? 169.609 132.451 127.165 1.00 133.20 ?  37  ASP A CB  1 
ATOM   249   N N   . HIS A 1 49  ? 167.993 134.165 129.460 1.00 132.30 ?  38  HIS A N   1 
ATOM   250   C CA  . HIS A 1 49  ? 167.574 135.444 130.015 1.00 132.30 ?  38  HIS A CA  1 
ATOM   251   C C   . HIS A 1 49  ? 168.157 135.638 131.410 1.00 132.30 ?  38  HIS A C   1 
ATOM   252   O O   . HIS A 1 49  ? 168.582 136.744 131.767 1.00 132.30 ?  38  HIS A O   1 
ATOM   253   C CB  . HIS A 1 49  ? 166.047 135.517 130.036 1.00 132.30 ?  38  HIS A CB  1 
ATOM   254   C CG  . HIS A 1 49  ? 165.507 136.877 130.347 1.00 132.30 ?  38  HIS A CG  1 
ATOM   255   N ND1 . HIS A 1 49  ? 164.157 137.156 130.347 1.00 132.30 ?  38  HIS A ND1 1 
ATOM   256   C CD2 . HIS A 1 49  ? 166.131 138.039 130.652 1.00 132.30 ?  38  HIS A CD2 1 
ATOM   257   C CE1 . HIS A 1 49  ? 163.974 138.428 130.647 1.00 132.30 ?  38  HIS A CE1 1 
ATOM   258   N NE2 . HIS A 1 49  ? 165.156 138.986 130.837 1.00 132.30 ?  38  HIS A NE2 1 
ATOM   259   N N   . LEU A 1 50  ? 168.243 134.539 132.148 1.00 131.46 ?  39  LEU A N   1 
ATOM   260   C CA  . LEU A 1 50  ? 168.867 134.551 133.457 1.00 131.46 ?  39  LEU A CA  1 
ATOM   261   C C   . LEU A 1 50  ? 170.388 134.683 133.285 1.00 131.46 ?  39  LEU A C   1 
ATOM   262   O O   . LEU A 1 50  ? 171.109 134.938 134.246 1.00 131.46 ?  39  LEU A O   1 
ATOM   263   C CB  . LEU A 1 50  ? 168.523 133.275 134.222 1.00 131.46 ?  39  LEU A CB  1 
ATOM   264   C CG  . LEU A 1 50  ? 167.045 133.096 134.579 1.00 131.46 ?  39  LEU A CG  1 
ATOM   265   C CD1 . LEU A 1 50  ? 166.796 131.735 135.204 1.00 131.46 ?  39  LEU A CD1 1 
ATOM   266   C CD2 . LEU A 1 50  ? 166.570 134.212 135.496 1.00 131.46 ?  39  LEU A CD2 1 
ATOM   267   N N   . LYS A 1 51  ? 170.866 134.504 132.053 1.00 130.44 ?  40  LYS A N   1 
ATOM   268   C CA  . LYS A 1 51  ? 172.284 134.615 131.737 1.00 130.44 ?  40  LYS A CA  1 
ATOM   269   C C   . LYS A 1 51  ? 172.666 136.074 131.518 1.00 130.44 ?  40  LYS A C   1 
ATOM   270   O O   . LYS A 1 51  ? 173.796 136.478 131.795 1.00 130.44 ?  40  LYS A O   1 
ATOM   271   C CB  . LYS A 1 51  ? 172.626 133.788 130.497 1.00 130.44 ?  40  LYS A CB  1 
ATOM   272   C CG  . LYS A 1 51  ? 173.950 134.155 129.843 1.00 130.44 ?  40  LYS A CG  1 
ATOM   273   C CD  . LYS A 1 51  ? 173.826 135.412 128.995 1.00 130.44 ?  40  LYS A CD  1 
ATOM   274   C CE  . LYS A 1 51  ? 175.143 135.774 128.331 1.00 130.44 ?  40  LYS A CE  1 
ATOM   275   N NZ  . LYS A 1 51  ? 175.042 137.030 127.537 1.00 130.44 1  40  LYS A NZ  1 
ATOM   276   N N   . VAL A 1 52  ? 171.704 136.855 131.033 1.00 129.13 ?  41  VAL A N   1 
ATOM   277   C CA  . VAL A 1 52  ? 171.904 138.273 130.802 1.00 129.13 ?  41  VAL A CA  1 
ATOM   278   C C   . VAL A 1 52  ? 171.683 139.024 132.111 1.00 129.13 ?  41  VAL A C   1 
ATOM   279   O O   . VAL A 1 52  ? 172.189 140.127 132.295 1.00 129.13 ?  41  VAL A O   1 
ATOM   280   C CB  . VAL A 1 52  ? 170.944 138.812 129.728 1.00 129.13 ?  41  VAL A CB  1 
ATOM   281   C CG1 . VAL A 1 52  ? 171.275 138.206 128.372 1.00 129.13 ?  41  VAL A CG1 1 
ATOM   282   C CG2 . VAL A 1 52  ? 169.501 138.522 130.109 1.00 129.13 ?  41  VAL A CG2 1 
ATOM   283   N N   . CYS A 1 53  ? 170.932 138.407 133.022 1.00 127.14 ?  42  CYS A N   1 
ATOM   284   C CA  . CYS A 1 53  ? 170.651 139.003 134.326 1.00 127.14 ?  42  CYS A CA  1 
ATOM   285   C C   . CYS A 1 53  ? 171.951 139.265 135.077 1.00 127.14 ?  42  CYS A C   1 
ATOM   286   O O   . CYS A 1 53  ? 172.125 140.325 135.677 1.00 127.14 ?  42  CYS A O   1 
ATOM   287   C CB  . CYS A 1 53  ? 169.737 138.097 135.159 1.00 127.14 ?  42  CYS A CB  1 
ATOM   288   S SG  . CYS A 1 53  ? 167.963 138.263 134.832 1.00 127.14 ?  42  CYS A SG  1 
ATOM   289   N N   . CYS A 1 54  ? 172.855 138.290 135.047 1.00 122.65 ?  43  CYS A N   1 
ATOM   290   C CA  . CYS A 1 54  ? 174.148 138.419 135.705 1.00 122.65 ?  43  CYS A CA  1 
ATOM   291   C C   . CYS A 1 54  ? 175.188 138.854 134.677 1.00 122.65 ?  43  CYS A C   1 
ATOM   292   O O   . CYS A 1 54  ? 176.123 138.118 134.374 1.00 122.65 ?  43  CYS A O   1 
ATOM   293   C CB  . CYS A 1 54  ? 174.550 137.089 136.339 1.00 122.65 ?  43  CYS A CB  1 
ATOM   294   S SG  . CYS A 1 54  ? 176.101 137.128 137.266 1.00 122.65 ?  43  CYS A SG  1 
ATOM   295   N N   . SER A 1 55  ? 175.015 140.063 134.151 1.00 117.13 ?  44  SER A N   1 
ATOM   296   C CA  . SER A 1 55  ? 175.902 140.620 133.132 1.00 117.13 ?  44  SER A CA  1 
ATOM   297   C C   . SER A 1 55  ? 177.325 140.941 133.602 1.00 117.13 ?  44  SER A C   1 
ATOM   298   O O   . SER A 1 55  ? 178.282 140.722 132.859 1.00 117.13 ?  44  SER A O   1 
ATOM   299   C CB  . SER A 1 55  ? 175.268 141.873 132.520 1.00 117.13 ?  44  SER A CB  1 
ATOM   300   N N   . CYS A 1 56  ? 177.448 141.468 134.816 1.00 114.83 ?  45  CYS A N   1 
ATOM   301   C CA  . CYS A 1 56  ? 178.741 141.833 135.398 1.00 114.83 ?  45  CYS A CA  1 
ATOM   302   C C   . CYS A 1 56  ? 179.600 142.666 134.453 1.00 114.83 ?  45  CYS A C   1 
ATOM   303   O O   . CYS A 1 56  ? 180.820 142.712 134.594 1.00 114.83 ?  45  CYS A O   1 
ATOM   304   C CB  . CYS A 1 56  ? 179.532 140.591 135.820 1.00 114.83 ?  45  CYS A CB  1 
ATOM   305   S SG  . CYS A 1 56  ? 178.537 139.194 136.381 1.00 114.83 ?  45  CYS A SG  1 
ATOM   306   N N   . SER A 1 57  ? 178.969 143.329 133.492 1.00 106.25 ?  46  SER A N   1 
ATOM   307   C CA  . SER A 1 57  ? 179.719 144.122 132.538 1.00 106.25 ?  46  SER A CA  1 
ATOM   308   C C   . SER A 1 57  ? 180.099 145.441 133.180 1.00 106.25 ?  46  SER A C   1 
ATOM   309   O O   . SER A 1 57  ? 179.469 145.866 134.146 1.00 106.25 ?  46  SER A O   1 
ATOM   310   C CB  . SER A 1 57  ? 178.880 144.365 131.286 1.00 106.25 ?  46  SER A CB  1 
ATOM   311   O OG  . SER A 1 57  ? 179.664 144.926 130.251 1.00 106.25 ?  46  SER A OG  1 
ATOM   312   N N   . PRO A 1 58  ? 181.151 146.084 132.671 1.00 102.80 ?  47  PRO A N   1 
ATOM   313   C CA  . PRO A 1 58  ? 181.515 147.386 133.262 1.00 102.80 ?  47  PRO A CA  1 
ATOM   314   C C   . PRO A 1 58  ? 180.452 148.451 133.063 1.00 102.80 ?  47  PRO A C   1 
ATOM   315   O O   . PRO A 1 58  ? 179.988 149.059 134.039 1.00 102.80 ?  47  PRO A O   1 
ATOM   316   C CB  . PRO A 1 58  ? 182.823 147.739 132.540 1.00 102.80 ?  47  PRO A CB  1 
ATOM   317   C CG  . PRO A 1 58  ? 183.370 146.438 132.083 1.00 102.80 ?  47  PRO A CG  1 
ATOM   318   C CD  . PRO A 1 58  ? 182.183 145.592 131.743 1.00 102.80 ?  47  PRO A CD  1 
ATOM   319   N N   . GLN A 1 59  ? 180.048 148.699 131.816 1.00 100.72 ?  48  GLN A N   1 
ATOM   320   C CA  . GLN A 1 59  ? 179.040 149.724 131.574 1.00 100.72 ?  48  GLN A CA  1 
ATOM   321   C C   . GLN A 1 59  ? 177.684 149.316 132.131 1.00 100.72 ?  48  GLN A C   1 
ATOM   322   O O   . GLN A 1 59  ? 176.884 150.180 132.504 1.00 100.72 ?  48  GLN A O   1 
ATOM   323   C CB  . GLN A 1 59  ? 178.946 150.049 130.079 1.00 100.72 ?  48  GLN A CB  1 
ATOM   324   C CG  . GLN A 1 59  ? 178.285 148.999 129.192 1.00 100.72 ?  48  GLN A CG  1 
ATOM   325   C CD  . GLN A 1 59  ? 179.013 147.670 129.181 1.00 100.72 ?  48  GLN A CD  1 
ATOM   326   O OE1 . GLN A 1 59  ? 180.225 147.609 129.392 1.00 100.72 ?  48  GLN A OE1 1 
ATOM   327   N NE2 . GLN A 1 59  ? 178.282 146.599 128.903 1.00 100.72 ?  48  GLN A NE2 1 
ATOM   328   N N   . LYS A 1 60  ? 177.413 148.012 132.224 1.00 98.51  ?  49  LYS A N   1 
ATOM   329   C CA  . LYS A 1 60  ? 176.171 147.560 132.842 1.00 98.51  ?  49  LYS A CA  1 
ATOM   330   C C   . LYS A 1 60  ? 176.129 147.930 134.320 1.00 98.51  ?  49  LYS A C   1 
ATOM   331   O O   . LYS A 1 60  ? 175.124 148.455 134.813 1.00 98.51  ?  49  LYS A O   1 
ATOM   332   C CB  . LYS A 1 60  ? 176.012 146.052 132.663 1.00 98.51  ?  49  LYS A CB  1 
ATOM   333   C CG  . LYS A 1 60  ? 174.741 145.489 133.268 1.00 98.51  ?  49  LYS A CG  1 
ATOM   334   C CD  . LYS A 1 60  ? 173.917 144.745 132.235 1.00 98.51  ?  49  LYS A CD  1 
ATOM   335   C CE  . LYS A 1 60  ? 172.810 143.950 132.896 1.00 98.51  ?  49  LYS A CE  1 
ATOM   336   N NZ  . LYS A 1 60  ? 173.319 143.183 134.065 1.00 98.51  1  49  LYS A NZ  1 
ATOM   337   N N   . ALA A 1 61  ? 177.215 147.661 135.046 1.00 93.48  ?  50  ALA A N   1 
ATOM   338   C CA  . ALA A 1 61  ? 177.268 148.049 136.450 1.00 93.48  ?  50  ALA A CA  1 
ATOM   339   C C   . ALA A 1 61  ? 177.228 149.563 136.601 1.00 93.48  ?  50  ALA A C   1 
ATOM   340   O O   . ALA A 1 61  ? 176.603 150.087 137.533 1.00 93.48  ?  50  ALA A O   1 
ATOM   341   C CB  . ALA A 1 61  ? 178.522 147.472 137.107 1.00 93.48  ?  50  ALA A CB  1 
ATOM   342   N N   . LYS A 1 62  ? 177.880 150.287 135.686 1.00 90.02  ?  51  LYS A N   1 
ATOM   343   C CA  . LYS A 1 62  ? 177.831 151.742 135.738 1.00 90.02  ?  51  LYS A CA  1 
ATOM   344   C C   . LYS A 1 62  ? 176.404 152.251 135.590 1.00 90.02  ?  51  LYS A C   1 
ATOM   345   O O   . LYS A 1 62  ? 175.970 153.124 136.351 1.00 90.02  ?  51  LYS A O   1 
ATOM   346   C CB  . LYS A 1 62  ? 178.726 152.342 134.656 1.00 90.02  ?  51  LYS A CB  1 
ATOM   347   C CG  . LYS A 1 62  ? 178.758 153.863 134.657 1.00 90.02  ?  51  LYS A CG  1 
ATOM   348   C CD  . LYS A 1 62  ? 177.966 154.437 133.492 1.00 90.02  ?  51  LYS A CD  1 
ATOM   349   C CE  . LYS A 1 62  ? 178.372 155.870 133.191 1.00 90.02  ?  51  LYS A CE  1 
ATOM   350   N NZ  . LYS A 1 62  ? 177.670 156.405 131.994 1.00 90.02  1  51  LYS A NZ  1 
ATOM   351   N N   . ARG A 1 63  ? 175.653 151.715 134.628 1.00 87.50  ?  52  ARG A N   1 
ATOM   352   C CA  . ARG A 1 63  ? 174.282 152.174 134.443 1.00 87.50  ?  52  ARG A CA  1 
ATOM   353   C C   . ARG A 1 63  ? 173.383 151.726 135.588 1.00 87.50  ?  52  ARG A C   1 
ATOM   354   O O   . ARG A 1 63  ? 172.446 152.442 135.946 1.00 87.50  ?  52  ARG A O   1 
ATOM   355   C CB  . ARG A 1 63  ? 173.735 151.703 133.094 1.00 87.50  ?  52  ARG A CB  1 
ATOM   356   C CG  . ARG A 1 63  ? 173.236 150.272 133.055 1.00 87.50  ?  52  ARG A CG  1 
ATOM   357   C CD  . ARG A 1 63  ? 172.478 149.997 131.767 1.00 87.50  ?  52  ARG A CD  1 
ATOM   358   N NE  . ARG A 1 63  ? 171.766 148.723 131.804 1.00 87.50  ?  52  ARG A NE  1 
ATOM   359   C CZ  . ARG A 1 63  ? 170.619 148.522 132.443 1.00 87.50  ?  52  ARG A CZ  1 
ATOM   360   N NH1 . ARG A 1 63  ? 170.046 147.327 132.417 1.00 87.50  1  52  ARG A NH1 1 
ATOM   361   N NH2 . ARG A 1 63  ? 170.045 149.514 133.109 1.00 87.50  ?  52  ARG A NH2 1 
ATOM   362   N N   . ILE A 1 64  ? 173.671 150.578 136.204 1.00 82.76  ?  53  ILE A N   1 
ATOM   363   C CA  . ILE A 1 64  ? 172.893 150.152 137.366 1.00 82.76  ?  53  ILE A CA  1 
ATOM   364   C C   . ILE A 1 64  ? 173.089 151.129 138.521 1.00 82.76  ?  53  ILE A C   1 
ATOM   365   O O   . ILE A 1 64  ? 172.125 151.558 139.171 1.00 82.76  ?  53  ILE A O   1 
ATOM   366   C CB  . ILE A 1 64  ? 173.272 148.716 137.770 1.00 82.76  ?  53  ILE A CB  1 
ATOM   367   C CG1 . ILE A 1 64  ? 172.739 147.713 136.748 1.00 82.76  ?  53  ILE A CG1 1 
ATOM   368   C CG2 . ILE A 1 64  ? 172.740 148.393 139.156 1.00 82.76  ?  53  ILE A CG2 1 
ATOM   369   C CD1 . ILE A 1 64  ? 171.238 147.668 136.665 1.00 82.76  ?  53  ILE A CD1 1 
ATOM   370   N N   . VAL A 1 65  ? 174.342 151.508 138.782 1.00 78.71  ?  54  VAL A N   1 
ATOM   371   C CA  . VAL A 1 65  ? 174.617 152.435 139.879 1.00 78.71  ?  54  VAL A CA  1 
ATOM   372   C C   . VAL A 1 65  ? 174.067 153.822 139.565 1.00 78.71  ?  54  VAL A C   1 
ATOM   373   O O   . VAL A 1 65  ? 173.603 154.537 140.460 1.00 78.71  ?  54  VAL A O   1 
ATOM   374   C CB  . VAL A 1 65  ? 176.126 152.469 140.183 1.00 78.71  ?  54  VAL A CB  1 
ATOM   375   C CG1 . VAL A 1 65  ? 176.419 153.425 141.325 1.00 78.71  ?  54  VAL A CG1 1 
ATOM   376   C CG2 . VAL A 1 65  ? 176.616 151.080 140.537 1.00 78.71  ?  54  VAL A CG2 1 
ATOM   377   N N   . LEU A 1 66  ? 174.101 154.225 138.293 1.00 76.53  ?  55  LEU A N   1 
ATOM   378   C CA  . LEU A 1 66  ? 173.537 155.520 137.933 1.00 76.53  ?  55  LEU A CA  1 
ATOM   379   C C   . LEU A 1 66  ? 172.015 155.503 137.982 1.00 76.53  ?  55  LEU A C   1 
ATOM   380   O O   . LEU A 1 66  ? 171.386 156.560 138.106 1.00 76.53  ?  55  LEU A O   1 
ATOM   381   C CB  . LEU A 1 66  ? 174.013 155.941 136.544 1.00 76.53  ?  55  LEU A CB  1 
ATOM   382   C CG  . LEU A 1 66  ? 175.381 156.616 136.466 1.00 76.53  ?  55  LEU A CG  1 
ATOM   383   C CD1 . LEU A 1 66  ? 175.518 157.401 135.176 1.00 76.53  ?  55  LEU A CD1 1 
ATOM   384   C CD2 . LEU A 1 66  ? 175.610 157.514 137.667 1.00 76.53  ?  55  LEU A CD2 1 
ATOM   385   N N   . SER A 1 67  ? 171.407 154.322 137.868 1.00 70.89  ?  56  SER A N   1 
ATOM   386   C CA  . SER A 1 67  ? 169.956 154.230 137.961 1.00 70.89  ?  56  SER A CA  1 
ATOM   387   C C   . SER A 1 67  ? 169.501 154.149 139.410 1.00 70.89  ?  56  SER A C   1 
ATOM   388   O O   . SER A 1 67  ? 168.364 154.509 139.725 1.00 70.89  ?  56  SER A O   1 
ATOM   389   C CB  . SER A 1 67  ? 169.456 153.021 137.176 1.00 70.89  ?  56  SER A CB  1 
ATOM   390   O OG  . SER A 1 67  ? 169.490 153.272 135.784 1.00 70.89  ?  56  SER A OG  1 
ATOM   391   N N   . LEU A 1 68  ? 170.369 153.674 140.303 1.00 65.27  ?  57  LEU A N   1 
ATOM   392   C CA  . LEU A 1 68  ? 170.022 153.641 141.719 1.00 65.27  ?  57  LEU A CA  1 
ATOM   393   C C   . LEU A 1 68  ? 170.329 154.944 142.439 1.00 65.27  ?  57  LEU A C   1 
ATOM   394   O O   . LEU A 1 68  ? 169.901 155.113 143.583 1.00 65.27  ?  57  LEU A O   1 
ATOM   395   C CB  . LEU A 1 68  ? 170.757 152.499 142.421 1.00 65.27  ?  57  LEU A CB  1 
ATOM   396   C CG  . LEU A 1 68  ? 170.178 151.097 142.243 1.00 65.27  ?  57  LEU A CG  1 
ATOM   397   C CD1 . LEU A 1 68  ? 171.230 150.061 142.576 1.00 65.27  ?  57  LEU A CD1 1 
ATOM   398   C CD2 . LEU A 1 68  ? 168.949 150.910 143.112 1.00 65.27  ?  57  LEU A CD2 1 
ATOM   399   N N   . PHE A 1 69  ? 171.055 155.859 141.803 1.00 62.35  ?  58  PHE A N   1 
ATOM   400   C CA  . PHE A 1 69  ? 171.468 157.121 142.420 1.00 62.35  ?  58  PHE A CA  1 
ATOM   401   C C   . PHE A 1 69  ? 171.268 158.236 141.405 1.00 62.35  ?  58  PHE A C   1 
ATOM   402   O O   . PHE A 1 69  ? 172.231 158.766 140.841 1.00 62.35  ?  58  PHE A O   1 
ATOM   403   C CB  . PHE A 1 69  ? 172.924 157.046 142.878 1.00 62.35  ?  58  PHE A CB  1 
ATOM   404   C CG  . PHE A 1 69  ? 173.191 157.741 144.175 1.00 62.35  ?  58  PHE A CG  1 
ATOM   405   C CD1 . PHE A 1 69  ? 174.030 158.839 144.225 1.00 62.35  ?  58  PHE A CD1 1 
ATOM   406   C CD2 . PHE A 1 69  ? 172.613 157.296 145.347 1.00 62.35  ?  58  PHE A CD2 1 
ATOM   407   C CE1 . PHE A 1 69  ? 174.284 159.482 145.418 1.00 62.35  ?  58  PHE A CE1 1 
ATOM   408   C CE2 . PHE A 1 69  ? 172.860 157.934 146.542 1.00 62.35  ?  58  PHE A CE2 1 
ATOM   409   C CZ  . PHE A 1 69  ? 173.698 159.029 146.577 1.00 62.35  ?  58  PHE A CZ  1 
ATOM   410   N N   . PRO A 1 70  ? 170.016 158.613 141.140 1.00 58.18  ?  59  PRO A N   1 
ATOM   411   C CA  . PRO A 1 70  ? 169.757 159.567 140.052 1.00 58.18  ?  59  PRO A CA  1 
ATOM   412   C C   . PRO A 1 70  ? 170.431 160.916 140.222 1.00 58.18  ?  59  PRO A C   1 
ATOM   413   O O   . PRO A 1 70  ? 170.677 161.591 139.216 1.00 58.18  ?  59  PRO A O   1 
ATOM   414   C CB  . PRO A 1 70  ? 168.229 159.693 140.071 1.00 58.18  ?  59  PRO A CB  1 
ATOM   415   C CG  . PRO A 1 70  ? 167.772 158.404 140.611 1.00 58.18  ?  59  PRO A CG  1 
ATOM   416   C CD  . PRO A 1 70  ? 168.762 158.063 141.678 1.00 58.18  ?  59  PRO A CD  1 
ATOM   417   N N   . ILE A 1 71  ? 170.746 161.332 141.451 1.00 58.48  ?  60  ILE A N   1 
ATOM   418   C CA  . ILE A 1 71  ? 171.346 162.650 141.639 1.00 58.48  ?  60  ILE A CA  1 
ATOM   419   C C   . ILE A 1 71  ? 172.707 162.730 140.961 1.00 58.48  ?  60  ILE A C   1 
ATOM   420   O O   . ILE A 1 71  ? 173.138 163.811 140.547 1.00 58.48  ?  60  ILE A O   1 
ATOM   421   C CB  . ILE A 1 71  ? 171.437 163.000 143.135 1.00 58.48  ?  60  ILE A CB  1 
ATOM   422   C CG1 . ILE A 1 71  ? 171.816 164.473 143.314 1.00 58.48  ?  60  ILE A CG1 1 
ATOM   423   C CG2 . ILE A 1 71  ? 172.426 162.097 143.840 1.00 58.48  ?  60  ILE A CG2 1 
ATOM   424   C CD1 . ILE A 1 71  ? 171.612 164.997 144.706 1.00 58.48  ?  60  ILE A CD1 1 
ATOM   425   N N   . ALA A 1 72  ? 173.395 161.598 140.813 1.00 61.88  ?  61  ALA A N   1 
ATOM   426   C CA  . ALA A 1 72  ? 174.684 161.584 140.140 1.00 61.88  ?  61  ALA A CA  1 
ATOM   427   C C   . ALA A 1 72  ? 174.569 161.869 138.652 1.00 61.88  ?  61  ALA A C   1 
ATOM   428   O O   . ALA A 1 72  ? 175.596 162.081 138.001 1.00 61.88  ?  61  ALA A O   1 
ATOM   429   C CB  . ALA A 1 72  ? 175.372 160.237 140.356 1.00 61.88  ?  61  ALA A CB  1 
ATOM   430   N N   . SER A 1 73  ? 173.356 161.886 138.106 1.00 63.34  ?  62  SER A N   1 
ATOM   431   C CA  . SER A 1 73  ? 173.143 162.119 136.686 1.00 63.34  ?  62  SER A CA  1 
ATOM   432   C C   . SER A 1 73  ? 172.466 163.441 136.371 1.00 63.34  ?  62  SER A C   1 
ATOM   433   O O   . SER A 1 73  ? 172.699 163.990 135.293 1.00 63.34  ?  62  SER A O   1 
ATOM   434   C CB  . SER A 1 73  ? 172.313 160.980 136.083 1.00 63.34  ?  62  SER A CB  1 
ATOM   435   O OG  . SER A 1 73  ? 170.931 161.195 136.294 1.00 63.34  ?  62  SER A OG  1 
ATOM   436   N N   . TRP A 1 74  ? 171.637 163.975 137.271 1.00 59.97  ?  63  TRP A N   1 
ATOM   437   C CA  . TRP A 1 74  ? 170.965 165.240 136.999 1.00 59.97  ?  63  TRP A CA  1 
ATOM   438   C C   . TRP A 1 74  ? 171.604 166.433 137.691 1.00 59.97  ?  63  TRP A C   1 
ATOM   439   O O   . TRP A 1 74  ? 171.308 167.570 137.316 1.00 59.97  ?  63  TRP A O   1 
ATOM   440   C CB  . TRP A 1 74  ? 169.476 165.168 137.381 1.00 59.97  ?  63  TRP A CB  1 
ATOM   441   C CG  . TRP A 1 74  ? 169.154 165.058 138.852 1.00 59.97  ?  63  TRP A CG  1 
ATOM   442   C CD1 . TRP A 1 74  ? 168.773 163.933 139.515 1.00 59.97  ?  63  TRP A CD1 1 
ATOM   443   C CD2 . TRP A 1 74  ? 169.136 166.115 139.820 1.00 59.97  ?  63  TRP A CD2 1 
ATOM   444   N NE1 . TRP A 1 74  ? 168.541 164.215 140.835 1.00 59.97  ?  63  TRP A NE1 1 
ATOM   445   C CE2 . TRP A 1 74  ? 168.756 165.550 141.048 1.00 59.97  ?  63  TRP A CE2 1 
ATOM   446   C CE3 . TRP A 1 74  ? 169.414 167.482 139.772 1.00 59.97  ?  63  TRP A CE3 1 
ATOM   447   C CZ2 . TRP A 1 74  ? 168.653 166.298 142.213 1.00 59.97  ?  63  TRP A CZ2 1 
ATOM   448   C CZ3 . TRP A 1 74  ? 169.312 168.221 140.927 1.00 59.97  ?  63  TRP A CZ3 1 
ATOM   449   C CH2 . TRP A 1 74  ? 168.935 167.629 142.130 1.00 59.97  ?  63  TRP A CH2 1 
ATOM   450   N N   . LEU A 1 75  ? 172.464 166.215 138.676 1.00 61.43  ?  64  LEU A N   1 
ATOM   451   C CA  . LEU A 1 75  ? 173.099 167.339 139.354 1.00 61.43  ?  64  LEU A CA  1 
ATOM   452   C C   . LEU A 1 75  ? 174.244 167.924 138.531 1.00 61.43  ?  64  LEU A C   1 
ATOM   453   O O   . LEU A 1 75  ? 174.328 169.151 138.408 1.00 61.43  ?  64  LEU A O   1 
ATOM   454   C CB  . LEU A 1 75  ? 173.591 166.936 140.744 1.00 61.43  ?  64  LEU A CB  1 
ATOM   455   C CG  . LEU A 1 75  ? 174.118 168.085 141.599 1.00 61.43  ?  64  LEU A CG  1 
ATOM   456   C CD1 . LEU A 1 75  ? 173.049 169.146 141.779 1.00 61.43  ?  64  LEU A CD1 1 
ATOM   457   C CD2 . LEU A 1 75  ? 174.595 167.574 142.941 1.00 61.43  ?  64  LEU A CD2 1 
ATOM   458   N N   . PRO A 1 76  ? 175.153 167.119 137.965 1.00 64.25  ?  65  PRO A N   1 
ATOM   459   C CA  . PRO A 1 76  ? 176.188 167.712 137.101 1.00 64.25  ?  65  PRO A CA  1 
ATOM   460   C C   . PRO A 1 76  ? 175.627 168.381 135.862 1.00 64.25  ?  65  PRO A C   1 
ATOM   461   O O   . PRO A 1 76  ? 176.256 169.309 135.339 1.00 64.25  ?  65  PRO A O   1 
ATOM   462   C CB  . PRO A 1 76  ? 177.073 166.514 136.738 1.00 64.25  ?  65  PRO A CB  1 
ATOM   463   C CG  . PRO A 1 76  ? 176.823 165.527 137.799 1.00 64.25  ?  65  PRO A CG  1 
ATOM   464   C CD  . PRO A 1 76  ? 175.382 165.675 138.136 1.00 64.25  ?  65  PRO A CD  1 
ATOM   465   N N   . ALA A 1 77  ? 174.463 167.948 135.381 1.00 66.52  ?  66  ALA A N   1 
ATOM   466   C CA  . ALA A 1 77  ? 173.815 168.532 134.216 1.00 66.52  ?  66  ALA A CA  1 
ATOM   467   C C   . ALA A 1 77  ? 172.910 169.699 134.589 1.00 66.52  ?  66  ALA A C   1 
ATOM   468   O O   . ALA A 1 77  ? 171.963 170.010 133.859 1.00 66.52  ?  66  ALA A O   1 
ATOM   469   C CB  . ALA A 1 77  ? 173.023 167.465 133.464 1.00 66.52  ?  66  ALA A CB  1 
ATOM   470   N N   . TYR A 1 78  ? 173.182 170.347 135.717 1.00 67.46  ?  67  TYR A N   1 
ATOM   471   C CA  . TYR A 1 78  ? 172.341 171.431 136.199 1.00 67.46  ?  67  TYR A CA  1 
ATOM   472   C C   . TYR A 1 78  ? 172.591 172.700 135.401 1.00 67.46  ?  67  TYR A C   1 
ATOM   473   O O   . TYR A 1 78  ? 173.734 173.028 135.071 1.00 67.46  ?  67  TYR A O   1 
ATOM   474   C CB  . TYR A 1 78  ? 172.607 171.687 137.681 1.00 67.46  ?  67  TYR A CB  1 
ATOM   475   C CG  . TYR A 1 78  ? 171.450 172.328 138.398 1.00 67.46  ?  67  TYR A CG  1 
ATOM   476   C CD1 . TYR A 1 78  ? 170.414 171.564 138.896 1.00 67.46  ?  67  TYR A CD1 1 
ATOM   477   C CD2 . TYR A 1 78  ? 171.392 173.701 138.574 1.00 67.46  ?  67  TYR A CD2 1 
ATOM   478   C CE1 . TYR A 1 78  ? 169.357 172.144 139.544 1.00 67.46  ?  67  TYR A CE1 1 
ATOM   479   C CE2 . TYR A 1 78  ? 170.338 174.289 139.224 1.00 67.46  ?  67  TYR A CE2 1 
ATOM   480   C CZ  . TYR A 1 78  ? 169.323 173.507 139.704 1.00 67.46  ?  67  TYR A CZ  1 
ATOM   481   O OH  . TYR A 1 78  ? 168.264 174.090 140.356 1.00 67.46  ?  67  TYR A OH  1 
ATOM   482   N N   . ARG A 1 79  ? 171.509 173.400 135.079 1.00 73.72  ?  68  ARG A N   1 
ATOM   483   C CA  . ARG A 1 79  ? 171.580 174.661 134.356 1.00 73.72  ?  68  ARG A CA  1 
ATOM   484   C C   . ARG A 1 79  ? 171.398 175.733 135.416 1.00 73.72  ?  68  ARG A C   1 
ATOM   485   O O   . ARG A 1 79  ? 170.279 175.990 135.863 1.00 73.72  ?  68  ARG A O   1 
ATOM   486   C CB  . ARG A 1 79  ? 170.466 174.749 133.315 1.00 73.72  ?  68  ARG A CB  1 
ATOM   487   C CG  . ARG A 1 79  ? 170.485 173.627 132.289 1.00 73.72  ?  68  ARG A CG  1 
ATOM   488   C CD  . ARG A 1 79  ? 169.239 173.656 131.418 1.00 73.72  ?  68  ARG A CD  1 
ATOM   489   N NE  . ARG A 1 79  ? 169.090 174.924 130.712 1.00 73.72  ?  68  ARG A NE  1 
ATOM   490   C CZ  . ARG A 1 79  ? 168.065 175.224 129.922 1.00 73.72  ?  68  ARG A CZ  1 
ATOM   491   N NH1 . ARG A 1 79  ? 168.013 176.405 129.319 1.00 73.72  1  68  ARG A NH1 1 
ATOM   492   N NH2 . ARG A 1 79  ? 167.090 174.345 129.735 1.00 73.72  ?  68  ARG A NH2 1 
ATOM   493   N N   . LEU A 1 80  ? 172.496 176.362 135.823 1.00 74.90  ?  69  LEU A N   1 
ATOM   494   C CA  . LEU A 1 80  ? 172.431 177.360 136.887 1.00 74.90  ?  69  LEU A CA  1 
ATOM   495   C C   . LEU A 1 80  ? 171.649 178.595 136.462 1.00 74.90  ?  69  LEU A C   1 
ATOM   496   O O   . LEU A 1 80  ? 170.637 178.938 137.083 1.00 74.90  ?  69  LEU A O   1 
ATOM   497   C CB  . LEU A 1 80  ? 173.840 177.751 137.327 1.00 74.90  ?  69  LEU A CB  1 
ATOM   498   C CG  . LEU A 1 80  ? 174.230 177.357 138.750 1.00 74.90  ?  69  LEU A CG  1 
ATOM   499   C CD1 . LEU A 1 80  ? 174.208 175.850 138.910 1.00 74.90  ?  69  LEU A CD1 1 
ATOM   500   C CD2 . LEU A 1 80  ? 175.595 177.913 139.096 1.00 74.90  ?  69  LEU A CD2 1 
ATOM   501   N N   . LYS A 1 81  ? 172.092 179.268 135.397 1.00 79.67  ?  70  LYS A N   1 
ATOM   502   C CA  . LYS A 1 81  ? 171.513 180.562 135.046 1.00 79.67  ?  70  LYS A CA  1 
ATOM   503   C C   . LYS A 1 81  ? 170.061 180.433 134.601 1.00 79.67  ?  70  LYS A C   1 
ATOM   504   O O   . LYS A 1 81  ? 169.335 181.432 134.538 1.00 79.67  ?  70  LYS A O   1 
ATOM   505   C CB  . LYS A 1 81  ? 172.350 181.229 133.953 1.00 79.67  ?  70  LYS A CB  1 
ATOM   506   C CG  . LYS A 1 81  ? 172.234 182.745 133.931 1.00 79.67  ?  70  LYS A CG  1 
ATOM   507   C CD  . LYS A 1 81  ? 172.432 183.304 132.530 1.00 79.67  ?  70  LYS A CD  1 
ATOM   508   C CE  . LYS A 1 81  ? 173.887 183.671 132.286 1.00 79.67  ?  70  LYS A CE  1 
ATOM   509   N NZ  . LYS A 1 81  ? 174.161 185.103 132.588 1.00 79.67  1  70  LYS A NZ  1 
ATOM   510   N N   . GLU A 1 82  ? 169.615 179.221 134.287 1.00 78.04  ?  71  GLU A N   1 
ATOM   511   C CA  . GLU A 1 82  ? 168.258 179.009 133.808 1.00 78.04  ?  71  GLU A CA  1 
ATOM   512   C C   . GLU A 1 82  ? 167.334 178.386 134.847 1.00 78.04  ?  71  GLU A C   1 
ATOM   513   O O   . GLU A 1 82  ? 166.113 178.431 134.668 1.00 78.04  ?  71  GLU A O   1 
ATOM   514   C CB  . GLU A 1 82  ? 168.272 178.127 132.555 1.00 78.04  ?  71  GLU A CB  1 
ATOM   515   C CG  . GLU A 1 82  ? 168.549 178.883 131.267 1.00 78.04  ?  71  GLU A CG  1 
ATOM   516   C CD  . GLU A 1 82  ? 170.029 179.087 131.016 1.00 78.04  ?  71  GLU A CD  1 
ATOM   517   O OE1 . GLU A 1 82  ? 170.846 178.625 131.839 1.00 78.04  ?  71  GLU A OE1 1 
ATOM   518   O OE2 . GLU A 1 82  ? 170.377 179.710 129.990 1.00 78.04  -1 71  GLU A OE2 1 
ATOM   519   N N   . TRP A 1 83  ? 167.876 177.817 135.926 1.00 69.66  ?  72  TRP A N   1 
ATOM   520   C CA  . TRP A 1 83  ? 167.077 177.062 136.878 1.00 69.66  ?  72  TRP A CA  1 
ATOM   521   C C   . TRP A 1 83  ? 167.241 177.485 138.328 1.00 69.66  ?  72  TRP A C   1 
ATOM   522   O O   . TRP A 1 83  ? 166.350 177.192 139.131 1.00 69.66  ?  72  TRP A O   1 
ATOM   523   C CB  . TRP A 1 83  ? 167.411 175.565 136.795 1.00 69.66  ?  72  TRP A CB  1 
ATOM   524   C CG  . TRP A 1 83  ? 166.900 174.866 135.585 1.00 69.66  ?  72  TRP A CG  1 
ATOM   525   C CD1 . TRP A 1 83  ? 166.127 175.392 134.596 1.00 69.66  ?  72  TRP A CD1 1 
ATOM   526   C CD2 . TRP A 1 83  ? 167.129 173.502 135.233 1.00 69.66  ?  72  TRP A CD2 1 
ATOM   527   N NE1 . TRP A 1 83  ? 165.858 174.436 133.649 1.00 69.66  ?  72  TRP A NE1 1 
ATOM   528   C CE2 . TRP A 1 83  ? 166.463 173.265 134.018 1.00 69.66  ?  72  TRP A CE2 1 
ATOM   529   C CE3 . TRP A 1 83  ? 167.833 172.454 135.829 1.00 69.66  ?  72  TRP A CE3 1 
ATOM   530   C CZ2 . TRP A 1 83  ? 166.478 172.027 133.390 1.00 69.66  ?  72  TRP A CZ2 1 
ATOM   531   C CZ3 . TRP A 1 83  ? 167.849 171.226 135.205 1.00 69.66  ?  72  TRP A CZ3 1 
ATOM   532   C CH2 . TRP A 1 83  ? 167.176 171.021 133.997 1.00 69.66  ?  72  TRP A CH2 1 
ATOM   533   N N   . LEU A 1 84  ? 168.346 178.139 138.694 1.00 66.85  ?  73  LEU A N   1 
ATOM   534   C CA  . LEU A 1 84  ? 168.684 178.288 140.107 1.00 66.85  ?  73  LEU A CA  1 
ATOM   535   C C   . LEU A 1 84  ? 167.681 179.171 140.836 1.00 66.85  ?  73  LEU A C   1 
ATOM   536   O O   . LEU A 1 84  ? 167.162 178.795 141.892 1.00 66.85  ?  73  LEU A O   1 
ATOM   537   C CB  . LEU A 1 84  ? 170.096 178.852 140.251 1.00 66.85  ?  73  LEU A CB  1 
ATOM   538   C CG  . LEU A 1 84  ? 170.562 179.006 141.697 1.00 66.85  ?  73  LEU A CG  1 
ATOM   539   C CD1 . LEU A 1 84  ? 170.592 177.660 142.392 1.00 66.85  ?  73  LEU A CD1 1 
ATOM   540   C CD2 . LEU A 1 84  ? 171.921 179.673 141.751 1.00 66.85  ?  73  LEU A CD2 1 
ATOM   541   N N   . LEU A 1 85  ? 167.406 180.359 140.301 1.00 63.00  ?  74  LEU A N   1 
ATOM   542   C CA  . LEU A 1 85  ? 166.534 181.291 141.007 1.00 63.00  ?  74  LEU A CA  1 
ATOM   543   C C   . LEU A 1 85  ? 165.097 180.787 141.032 1.00 63.00  ?  74  LEU A C   1 
ATOM   544   O O   . LEU A 1 85  ? 164.389 180.953 142.034 1.00 63.00  ?  74  LEU A O   1 
ATOM   545   C CB  . LEU A 1 85  ? 166.620 182.673 140.360 1.00 63.00  ?  74  LEU A CB  1 
ATOM   546   C CG  . LEU A 1 85  ? 165.685 183.765 140.872 1.00 63.00  ?  74  LEU A CG  1 
ATOM   547   C CD1 . LEU A 1 85  ? 166.483 185.022 141.132 1.00 63.00  ?  74  LEU A CD1 1 
ATOM   548   C CD2 . LEU A 1 85  ? 164.580 184.045 139.874 1.00 63.00  ?  74  LEU A CD2 1 
ATOM   549   N N   . SER A 1 86  ? 164.651 180.162 139.943 1.00 61.58  ?  75  SER A N   1 
ATOM   550   C CA  . SER A 1 86  ? 163.317 179.574 139.925 1.00 61.58  ?  75  SER A CA  1 
ATOM   551   C C   . SER A 1 86  ? 163.195 178.463 140.956 1.00 61.58  ?  75  SER A C   1 
ATOM   552   O O   . SER A 1 86  ? 162.186 178.373 141.661 1.00 61.58  ?  75  SER A O   1 
ATOM   553   C CB  . SER A 1 86  ? 162.995 179.049 138.529 1.00 61.58  ?  75  SER A CB  1 
ATOM   554   O OG  . SER A 1 86  ? 163.416 179.963 137.533 1.00 61.58  ?  75  SER A OG  1 
ATOM   555   N N   . ASP A 1 87  ? 164.221 177.616 141.072 1.00 58.42  ?  76  ASP A N   1 
ATOM   556   C CA  . ASP A 1 87  ? 164.192 176.564 142.079 1.00 58.42  ?  76  ASP A CA  1 
ATOM   557   C C   . ASP A 1 87  ? 164.235 177.134 143.488 1.00 58.42  ?  76  ASP A C   1 
ATOM   558   O O   . ASP A 1 87  ? 163.572 176.608 144.383 1.00 58.42  ?  76  ASP A O   1 
ATOM   559   C CB  . ASP A 1 87  ? 165.352 175.598 141.862 1.00 58.42  ?  76  ASP A CB  1 
ATOM   560   C CG  . ASP A 1 87  ? 164.909 174.292 141.251 1.00 58.42  ?  76  ASP A CG  1 
ATOM   561   O OD1 . ASP A 1 87  ? 163.714 173.958 141.368 1.00 58.42  ?  76  ASP A OD1 1 
ATOM   562   O OD2 . ASP A 1 87  ? 165.754 173.595 140.657 1.00 58.42  -1 76  ASP A OD2 1 
ATOM   563   N N   . ILE A 1 88  ? 164.983 178.217 143.701 1.00 56.95  ?  77  ILE A N   1 
ATOM   564   C CA  . ILE A 1 88  ? 165.027 178.849 145.016 1.00 56.95  ?  77  ILE A CA  1 
ATOM   565   C C   . ILE A 1 88  ? 163.649 179.369 145.407 1.00 56.95  ?  77  ILE A C   1 
ATOM   566   O O   . ILE A 1 88  ? 163.160 179.105 146.511 1.00 56.95  ?  77  ILE A O   1 
ATOM   567   C CB  . ILE A 1 88  ? 166.077 179.973 145.035 1.00 56.95  ?  77  ILE A CB  1 
ATOM   568   C CG1 . ILE A 1 88  ? 167.487 179.387 145.031 1.00 56.95  ?  77  ILE A CG1 1 
ATOM   569   C CG2 . ILE A 1 88  ? 165.886 180.857 146.246 1.00 56.95  ?  77  ILE A CG2 1 
ATOM   570   C CD1 . ILE A 1 88  ? 168.577 180.426 144.942 1.00 56.95  ?  77  ILE A CD1 1 
ATOM   571   N N   . VAL A 1 89  ? 163.000 180.113 144.509 1.00 56.34  ?  78  VAL A N   1 
ATOM   572   C CA  . VAL A 1 89  ? 161.681 180.667 144.811 1.00 56.34  ?  78  VAL A CA  1 
ATOM   573   C C   . VAL A 1 89  ? 160.659 179.554 145.022 1.00 56.34  ?  78  VAL A C   1 
ATOM   574   O O   . VAL A 1 89  ? 159.868 179.582 145.981 1.00 56.34  ?  78  VAL A O   1 
ATOM   575   C CB  . VAL A 1 89  ? 161.249 181.632 143.692 1.00 56.34  ?  78  VAL A CB  1 
ATOM   576   C CG1 . VAL A 1 89  ? 159.774 181.950 143.801 1.00 56.34  ?  78  VAL A CG1 1 
ATOM   577   C CG2 . VAL A 1 89  ? 162.078 182.898 143.750 1.00 56.34  ?  78  VAL A CG2 1 
ATOM   578   N N   . SER A 1 90  ? 160.654 178.561 144.131 1.00 55.19  ?  79  SER A N   1 
ATOM   579   C CA  . SER A 1 90  ? 159.729 177.445 144.261 1.00 55.19  ?  79  SER A CA  1 
ATOM   580   C C   . SER A 1 90  ? 159.946 176.696 145.565 1.00 55.19  ?  79  SER A C   1 
ATOM   581   O O   . SER A 1 90  ? 158.980 176.278 146.211 1.00 55.19  ?  79  SER A O   1 
ATOM   582   C CB  . SER A 1 90  ? 159.887 176.504 143.073 1.00 55.19  ?  79  SER A CB  1 
ATOM   583   O OG  . SER A 1 90  ? 159.434 175.204 143.389 1.00 55.19  ?  79  SER A OG  1 
ATOM   584   N N   . GLY A 1 91  ? 161.204 176.524 145.975 1.00 53.46  ?  80  GLY A N   1 
ATOM   585   C CA  . GLY A 1 91  ? 161.480 175.825 147.213 1.00 53.46  ?  80  GLY A CA  1 
ATOM   586   C C   . GLY A 1 91  ? 161.039 176.604 148.431 1.00 53.46  ?  80  GLY A C   1 
ATOM   587   O O   . GLY A 1 91  ? 160.472 176.036 149.364 1.00 53.46  ?  80  GLY A O   1 
ATOM   588   N N   . ILE A 1 92  ? 161.293 177.914 148.444 1.00 52.86  ?  81  ILE A N   1 
ATOM   589   C CA  . ILE A 1 92  ? 160.787 178.760 149.523 1.00 52.86  ?  81  ILE A CA  1 
ATOM   590   C C   . ILE A 1 92  ? 159.282 178.581 149.668 1.00 52.86  ?  81  ILE A C   1 
ATOM   591   O O   . ILE A 1 92  ? 158.767 178.325 150.767 1.00 52.86  ?  81  ILE A O   1 
ATOM   592   C CB  . ILE A 1 92  ? 161.147 180.234 149.272 1.00 52.86  ?  81  ILE A CB  1 
ATOM   593   C CG1 . ILE A 1 92  ? 162.662 180.433 149.230 1.00 52.86  ?  81  ILE A CG1 1 
ATOM   594   C CG2 . ILE A 1 92  ? 160.521 181.115 150.333 1.00 52.86  ?  81  ILE A CG2 1 
ATOM   595   C CD1 . ILE A 1 92  ? 163.312 180.525 150.575 1.00 52.86  ?  81  ILE A CD1 1 
ATOM   596   N N   . SER A 1 93  ? 158.552 178.700 148.555 1.00 52.78  ?  82  SER A N   1 
ATOM   597   C CA  . SER A 1 93  ? 157.096 178.633 148.621 1.00 52.78  ?  82  SER A CA  1 
ATOM   598   C C   . SER A 1 93  ? 156.614 177.261 149.079 1.00 52.78  ?  82  SER A C   1 
ATOM   599   O O   . SER A 1 93  ? 155.761 177.153 149.971 1.00 52.78  ?  82  SER A O   1 
ATOM   600   C CB  . SER A 1 93  ? 156.498 178.990 147.263 1.00 52.78  ?  82  SER A CB  1 
ATOM   601   O OG  . SER A 1 93  ? 157.252 180.014 146.642 1.00 52.78  ?  82  SER A OG  1 
ATOM   602   N N   . THR A 1 94  ? 157.139 176.191 148.479 1.00 53.16  ?  83  THR A N   1 
ATOM   603   C CA  . THR A 1 94  ? 156.636 174.871 148.838 1.00 53.16  ?  83  THR A CA  1 
ATOM   604   C C   . THR A 1 94  ? 157.078 174.465 150.236 1.00 53.16  ?  83  THR A C   1 
ATOM   605   O O   . THR A 1 94  ? 156.405 173.657 150.875 1.00 53.16  ?  83  THR A O   1 
ATOM   606   C CB  . THR A 1 94  ? 157.068 173.816 147.824 1.00 53.16  ?  83  THR A CB  1 
ATOM   607   O OG1 . THR A 1 94  ? 156.520 172.552 148.214 1.00 53.16  ?  83  THR A OG1 1 
ATOM   608   C CG2 . THR A 1 94  ? 158.573 173.680 147.796 1.00 53.16  ?  83  THR A CG2 1 
ATOM   609   N N   . GLY A 1 95  ? 158.166 175.036 150.756 1.00 51.84  ?  84  GLY A N   1 
ATOM   610   C CA  . GLY A 1 95  ? 158.535 174.753 152.132 1.00 51.84  ?  84  GLY A CA  1 
ATOM   611   C C   . GLY A 1 95  ? 157.651 175.475 153.125 1.00 51.84  ?  84  GLY A C   1 
ATOM   612   O O   . GLY A 1 95  ? 157.280 174.922 154.167 1.00 51.84  ?  84  GLY A O   1 
ATOM   613   N N   . ILE A 1 96  ? 157.292 176.722 152.816 1.00 51.60  ?  85  ILE A N   1 
ATOM   614   C CA  . ILE A 1 96  ? 156.343 177.438 153.660 1.00 51.60  ?  85  ILE A CA  1 
ATOM   615   C C   . ILE A 1 96  ? 154.996 176.725 153.665 1.00 51.60  ?  85  ILE A C   1 
ATOM   616   O O   . ILE A 1 96  ? 154.299 176.693 154.684 1.00 51.60  ?  85  ILE A O   1 
ATOM   617   C CB  . ILE A 1 96  ? 156.223 178.901 153.198 1.00 51.60  ?  85  ILE A CB  1 
ATOM   618   C CG1 . ILE A 1 96  ? 157.498 179.665 153.547 1.00 51.60  ?  85  ILE A CG1 1 
ATOM   619   C CG2 . ILE A 1 96  ? 155.031 179.561 153.833 1.00 51.60  ?  85  ILE A CG2 1 
ATOM   620   C CD1 . ILE A 1 96  ? 157.402 181.146 153.308 1.00 51.60  ?  85  ILE A CD1 1 
ATOM   621   N N   . VAL A 1 97  ? 154.617 176.125 152.536 1.00 51.90  ?  86  VAL A N   1 
ATOM   622   C CA  . VAL A 1 97  ? 153.381 175.346 152.510 1.00 51.90  ?  86  VAL A CA  1 
ATOM   623   C C   . VAL A 1 97  ? 153.549 174.019 153.248 1.00 51.90  ?  86  VAL A C   1 
ATOM   624   O O   . VAL A 1 97  ? 152.623 173.555 153.928 1.00 51.90  ?  86  VAL A O   1 
ATOM   625   C CB  . VAL A 1 97  ? 152.920 175.143 151.053 1.00 51.90  ?  86  VAL A CB  1 
ATOM   626   C CG1 . VAL A 1 97  ? 151.965 173.978 150.941 1.00 51.90  ?  86  VAL A CG1 1 
ATOM   627   C CG2 . VAL A 1 97  ? 152.267 176.405 150.528 1.00 51.90  ?  86  VAL A CG2 1 
ATOM   628   N N   . ALA A 1 98  ? 154.731 173.403 153.153 1.00 50.57  ?  87  ALA A N   1 
ATOM   629   C CA  . ALA A 1 98  ? 154.958 172.091 153.743 1.00 50.57  ?  87  ALA A CA  1 
ATOM   630   C C   . ALA A 1 98  ? 154.997 172.142 155.260 1.00 50.57  ?  87  ALA A C   1 
ATOM   631   O O   . ALA A 1 98  ? 154.601 171.175 155.910 1.00 50.57  ?  87  ALA A O   1 
ATOM   632   C CB  . ALA A 1 98  ? 156.260 171.496 153.213 1.00 50.57  ?  87  ALA A CB  1 
ATOM   633   N N   . VAL A 1 99  ? 155.466 173.247 155.840 1.00 49.83  ?  88  VAL A N   1 
ATOM   634   C CA  . VAL A 1 99  ? 155.435 173.384 157.297 1.00 49.83  ?  88  VAL A CA  1 
ATOM   635   C C   . VAL A 1 99  ? 154.005 173.256 157.813 1.00 49.83  ?  88  VAL A C   1 
ATOM   636   O O   . VAL A 1 99  ? 153.705 172.439 158.698 1.00 49.83  ?  88  VAL A O   1 
ATOM   637   C CB  . VAL A 1 99  ? 156.065 174.721 157.722 1.00 49.83  ?  88  VAL A CB  1 
ATOM   638   C CG1 . VAL A 1 99  ? 155.711 175.034 159.160 1.00 49.83  ?  88  VAL A CG1 1 
ATOM   639   C CG2 . VAL A 1 99  ? 157.563 174.680 157.537 1.00 49.83  ?  88  VAL A CG2 1 
ATOM   640   N N   . LEU A 1 100 ? 153.095 174.055 157.252 1.00 49.07  ?  89  LEU A N   1 
ATOM   641   C CA  . LEU A 1 100 ? 151.713 174.070 157.717 1.00 49.07  ?  89  LEU A CA  1 
ATOM   642   C C   . LEU A 1 100 ? 151.003 172.769 157.381 1.00 49.07  ?  89  LEU A C   1 
ATOM   643   O O   . LEU A 1 100 ? 150.206 172.265 158.183 1.00 49.07  ?  89  LEU A O   1 
ATOM   644   C CB  . LEU A 1 100 ? 150.978 175.256 157.102 1.00 49.07  ?  89  LEU A CB  1 
ATOM   645   C CG  . LEU A 1 100 ? 151.750 176.568 157.204 1.00 49.07  ?  89  LEU A CG  1 
ATOM   646   C CD1 . LEU A 1 100 ? 151.094 177.636 156.360 1.00 49.07  ?  89  LEU A CD1 1 
ATOM   647   C CD2 . LEU A 1 100 ? 151.857 177.007 158.648 1.00 49.07  ?  89  LEU A CD2 1 
ATOM   648   N N   . GLN A 1 101 ? 151.276 172.206 156.204 1.00 48.88  ?  90  GLN A N   1 
ATOM   649   C CA  . GLN A 1 101 ? 150.677 170.921 155.870 1.00 48.88  ?  90  GLN A CA  1 
ATOM   650   C C   . GLN A 1 101 ? 151.160 169.823 156.806 1.00 48.88  ?  90  GLN A C   1 
ATOM   651   O O   . GLN A 1 101 ? 150.370 168.961 157.198 1.00 48.88  ?  90  GLN A O   1 
ATOM   652   C CB  . GLN A 1 101 ? 150.977 170.564 154.418 1.00 48.88  ?  90  GLN A CB  1 
ATOM   653   C CG  . GLN A 1 101 ? 150.247 171.438 153.425 1.00 48.88  ?  90  GLN A CG  1 
ATOM   654   C CD  . GLN A 1 101 ? 150.021 170.754 152.102 1.00 48.88  ?  90  GLN A CD  1 
ATOM   655   O OE1 . GLN A 1 101 ? 150.322 169.577 151.942 1.00 48.88  ?  90  GLN A OE1 1 
ATOM   656   N NE2 . GLN A 1 101 ? 149.483 171.490 151.142 1.00 48.88  ?  90  GLN A NE2 1 
ATOM   657   N N   . GLY A 1 102 ? 152.430 169.855 157.208 1.00 47.03  ?  91  GLY A N   1 
ATOM   658   C CA  . GLY A 1 102 ? 152.919 168.866 158.150 1.00 47.03  ?  91  GLY A CA  1 
ATOM   659   C C   . GLY A 1 102 ? 152.280 169.000 159.515 1.00 47.03  ?  91  GLY A C   1 
ATOM   660   O O   . GLY A 1 102 ? 151.930 168.001 160.142 1.00 47.03  ?  91  GLY A O   1 
ATOM   661   N N   . LEU A 1 103 ? 152.116 170.235 159.993 1.00 46.41  ?  92  LEU A N   1 
ATOM   662   C CA  . LEU A 1 103 ? 151.415 170.433 161.261 1.00 46.41  ?  92  LEU A CA  1 
ATOM   663   C C   . LEU A 1 103 ? 149.988 169.889 161.197 1.00 46.41  ?  92  LEU A C   1 
ATOM   664   O O   . LEU A 1 103 ? 149.551 169.138 162.083 1.00 46.41  ?  92  LEU A O   1 
ATOM   665   C CB  . LEU A 1 103 ? 151.408 171.913 161.638 1.00 46.41  ?  92  LEU A CB  1 
ATOM   666   C CG  . LEU A 1 103 ? 152.736 172.616 161.897 1.00 46.41  ?  92  LEU A CG  1 
ATOM   667   C CD1 . LEU A 1 103 ? 152.496 174.090 162.099 1.00 46.41  ?  92  LEU A CD1 1 
ATOM   668   C CD2 . LEU A 1 103 ? 153.428 172.036 163.098 1.00 46.41  ?  92  LEU A CD2 1 
ATOM   669   N N   . ALA A 1 104 ? 149.244 170.250 160.145 1.00 45.18  ?  93  ALA A N   1 
ATOM   670   C CA  . ALA A 1 104 ? 147.869 169.781 160.015 1.00 45.18  ?  93  ALA A CA  1 
ATOM   671   C C   . ALA A 1 104 ? 147.795 168.262 159.914 1.00 45.18  ?  93  ALA A C   1 
ATOM   672   O O   . ALA A 1 104 ? 146.885 167.630 160.465 1.00 45.18  ?  93  ALA A O   1 
ATOM   673   C CB  . ALA A 1 104 ? 147.214 170.430 158.800 1.00 45.18  ?  93  ALA A CB  1 
ATOM   674   N N   . PHE A 1 105 ? 148.743 167.646 159.219 1.00 45.35  ?  94  PHE A N   1 
ATOM   675   C CA  . PHE A 1 105 ? 148.661 166.203 159.052 1.00 45.35  ?  94  PHE A CA  1 
ATOM   676   C C   . PHE A 1 105 ? 149.126 165.469 160.300 1.00 45.35  ?  94  PHE A C   1 
ATOM   677   O O   . PHE A 1 105 ? 148.693 164.339 160.545 1.00 45.35  ?  94  PHE A O   1 
ATOM   678   C CB  . PHE A 1 105 ? 149.457 165.781 157.819 1.00 45.35  ?  94  PHE A CB  1 
ATOM   679   C CG  . PHE A 1 105 ? 149.004 166.452 156.553 1.00 45.35  ?  94  PHE A CG  1 
ATOM   680   C CD1 . PHE A 1 105 ? 147.750 167.027 156.469 1.00 45.35  ?  94  PHE A CD1 1 
ATOM   681   C CD2 . PHE A 1 105 ? 149.833 166.522 155.457 1.00 45.35  ?  94  PHE A CD2 1 
ATOM   682   C CE1 . PHE A 1 105 ? 147.335 167.654 155.322 1.00 45.35  ?  94  PHE A CE1 1 
ATOM   683   C CE2 . PHE A 1 105 ? 149.419 167.147 154.303 1.00 45.35  ?  94  PHE A CE2 1 
ATOM   684   C CZ  . PHE A 1 105 ? 148.168 167.711 154.237 1.00 45.35  ?  94  PHE A CZ  1 
ATOM   685   N N   . ALA A 1 106 ? 149.974 166.097 161.114 1.00 47.07  ?  95  ALA A N   1 
ATOM   686   C CA  . ALA A 1 106 ? 150.266 165.541 162.429 1.00 47.07  ?  95  ALA A CA  1 
ATOM   687   C C   . ALA A 1 106 ? 149.050 165.639 163.335 1.00 47.07  ?  95  ALA A C   1 
ATOM   688   O O   . ALA A 1 106 ? 148.873 164.814 164.237 1.00 47.07  ?  95  ALA A O   1 
ATOM   689   C CB  . ALA A 1 106 ? 151.463 166.250 163.053 1.00 47.07  ?  95  ALA A CB  1 
ATOM   690   N N   . LEU A 1 107 ? 148.207 166.651 163.122 1.00 46.90  ?  96  LEU A N   1 
ATOM   691   C CA  . LEU A 1 107 ? 146.886 166.635 163.754 1.00 46.90  ?  96  LEU A CA  1 
ATOM   692   C C   . LEU A 1 107 ? 146.079 165.427 163.293 1.00 46.90  ?  96  LEU A C   1 
ATOM   693   O O   . LEU A 1 107 ? 145.485 164.717 164.111 1.00 46.90  ?  96  LEU A O   1 
ATOM   694   C CB  . LEU A 1 107 ? 146.114 167.916 163.446 1.00 46.90  ?  96  LEU A CB  1 
ATOM   695   C CG  . LEU A 1 107 ? 146.560 169.237 164.052 1.00 46.90  ?  96  LEU A CG  1 
ATOM   696   C CD1 . LEU A 1 107 ? 145.561 170.314 163.695 1.00 46.90  ?  96  LEU A CD1 1 
ATOM   697   C CD2 . LEU A 1 107 ? 146.712 169.110 165.546 1.00 46.90  ?  96  LEU A CD2 1 
ATOM   698   N N   . LEU A 1 108 ? 146.037 165.193 161.981 1.00 47.93  ?  97  LEU A N   1 
ATOM   699   C CA  . LEU A 1 108 ? 145.296 164.049 161.445 1.00 47.93  ?  97  LEU A CA  1 
ATOM   700   C C   . LEU A 1 108 ? 145.787 162.719 162.009 1.00 47.93  ?  97  LEU A C   1 
ATOM   701   O O   . LEU A 1 108 ? 144.994 161.786 162.173 1.00 47.93  ?  97  LEU A O   1 
ATOM   702   C CB  . LEU A 1 108 ? 145.388 164.022 159.922 1.00 47.93  ?  97  LEU A CB  1 
ATOM   703   C CG  . LEU A 1 108 ? 144.443 164.957 159.178 1.00 47.93  ?  97  LEU A CG  1 
ATOM   704   C CD1 . LEU A 1 108 ? 144.554 164.746 157.684 1.00 47.93  ?  97  LEU A CD1 1 
ATOM   705   C CD2 . LEU A 1 108 ? 143.024 164.730 159.649 1.00 47.93  ?  97  LEU A CD2 1 
ATOM   706   N N   . VAL A 1 109 ? 147.088 162.597 162.283 1.00 50.17  ?  98  VAL A N   1 
ATOM   707   C CA  . VAL A 1 109 ? 147.638 161.365 162.850 1.00 50.17  ?  98  VAL A CA  1 
ATOM   708   C C   . VAL A 1 109 ? 147.416 161.269 164.357 1.00 50.17  ?  98  VAL A C   1 
ATOM   709   O O   . VAL A 1 109 ? 147.577 160.181 164.931 1.00 50.17  ?  98  VAL A O   1 
ATOM   710   C CB  . VAL A 1 109 ? 149.134 161.263 162.487 1.00 50.17  ?  98  VAL A CB  1 
ATOM   711   C CG1 . VAL A 1 109 ? 149.747 159.970 162.974 1.00 50.17  ?  98  VAL A CG1 1 
ATOM   712   C CG2 . VAL A 1 109 ? 149.299 161.346 160.997 1.00 50.17  ?  98  VAL A CG2 1 
ATOM   713   N N   . ASP A 1 110 ? 147.015 162.362 165.006 1.00 55.09  ?  99  ASP A N   1 
ATOM   714   C CA  . ASP A 1 110 ? 146.804 162.415 166.454 1.00 55.09  ?  99  ASP A CA  1 
ATOM   715   C C   . ASP A 1 110 ? 148.120 162.233 167.203 1.00 55.09  ?  99  ASP A C   1 
ATOM   716   O O   . ASP A 1 110 ? 148.220 161.451 168.148 1.00 55.09  ?  99  ASP A O   1 
ATOM   717   C CB  . ASP A 1 110 ? 145.763 161.392 166.916 1.00 55.09  ?  99  ASP A CB  1 
ATOM   718   C CG  . ASP A 1 110 ? 145.199 161.706 168.292 1.00 55.09  ?  99  ASP A CG  1 
ATOM   719   O OD1 . ASP A 1 110 ? 144.106 161.193 168.613 1.00 55.09  ?  99  ASP A OD1 1 
ATOM   720   O OD2 . ASP A 1 110 ? 145.832 162.471 169.049 1.00 55.09  -1 99  ASP A OD2 1 
ATOM   721   N N   . ILE A 1 111 ? 149.141 162.957 166.767 1.00 52.86  ?  100 ILE A N   1 
ATOM   722   C CA  . ILE A 1 111 ? 150.402 163.063 167.497 1.00 52.86  ?  100 ILE A CA  1 
ATOM   723   C C   . ILE A 1 111 ? 150.743 164.545 167.600 1.00 52.86  ?  100 ILE A C   1 
ATOM   724   O O   . ILE A 1 111 ? 150.108 165.380 166.940 1.00 52.86  ?  100 ILE A O   1 
ATOM   725   C CB  . ILE A 1 111 ? 151.530 162.258 166.809 1.00 52.86  ?  100 ILE A CB  1 
ATOM   726   C CG1 . ILE A 1 111 ? 151.782 162.773 165.393 1.00 52.86  ?  100 ILE A CG1 1 
ATOM   727   C CG2 . ILE A 1 111 ? 151.185 160.783 166.787 1.00 52.86  ?  100 ILE A CG2 1 
ATOM   728   C CD1 . ILE A 1 111 ? 152.690 161.893 164.587 1.00 52.86  ?  100 ILE A CD1 1 
ATOM   729   N N   . PRO A 1 112 ? 151.702 164.910 168.449 1.00 54.41  ?  101 PRO A N   1 
ATOM   730   C CA  . PRO A 1 112 ? 152.136 166.310 168.512 1.00 54.41  ?  101 PRO A CA  1 
ATOM   731   C C   . PRO A 1 112 ? 152.546 166.816 167.141 1.00 54.41  ?  101 PRO A C   1 
ATOM   732   O O   . PRO A 1 112 ? 152.978 166.033 166.284 1.00 54.41  ?  101 PRO A O   1 
ATOM   733   C CB  . PRO A 1 112 ? 153.328 166.260 169.475 1.00 54.41  ?  101 PRO A CB  1 
ATOM   734   C CG  . PRO A 1 112 ? 153.003 165.142 170.373 1.00 54.41  ?  101 PRO A CG  1 
ATOM   735   C CD  . PRO A 1 112 ? 152.313 164.111 169.527 1.00 54.41  ?  101 PRO A CD  1 
ATOM   736   N N   . PRO A 1 113 ? 152.427 168.122 166.892 1.00 53.16  ?  102 PRO A N   1 
ATOM   737   C CA  . PRO A 1 113 ? 152.571 168.623 165.518 1.00 53.16  ?  102 PRO A CA  1 
ATOM   738   C C   . PRO A 1 113 ? 154.004 168.747 165.021 1.00 53.16  ?  102 PRO A C   1 
ATOM   739   O O   . PRO A 1 113 ? 154.193 169.008 163.827 1.00 53.16  ?  102 PRO A O   1 
ATOM   740   C CB  . PRO A 1 113 ? 151.893 169.995 165.587 1.00 53.16  ?  102 PRO A CB  1 
ATOM   741   C CG  . PRO A 1 113 ? 152.072 170.425 166.982 1.00 53.16  ?  102 PRO A CG  1 
ATOM   742   C CD  . PRO A 1 113 ? 152.030 169.186 167.828 1.00 53.16  ?  102 PRO A CD  1 
ATOM   743   N N   . VAL A 1 114 ? 155.015 168.563 165.870 1.00 51.51  ?  103 VAL A N   1 
ATOM   744   C CA  . VAL A 1 114 ? 156.395 168.631 165.396 1.00 51.51  ?  103 VAL A CA  1 
ATOM   745   C C   . VAL A 1 114 ? 156.778 167.392 164.597 1.00 51.51  ?  103 VAL A C   1 
ATOM   746   O O   . VAL A 1 114 ? 157.681 167.450 163.749 1.00 51.51  ?  103 VAL A O   1 
ATOM   747   C CB  . VAL A 1 114 ? 157.345 168.848 166.587 1.00 51.51  ?  103 VAL A CB  1 
ATOM   748   C CG1 . VAL A 1 114 ? 157.388 167.620 167.470 1.00 51.51  ?  103 VAL A CG1 1 
ATOM   749   C CG2 . VAL A 1 114 ? 158.731 169.237 166.114 1.00 51.51  ?  103 VAL A CG2 1 
ATOM   750   N N   . TYR A 1 115 ? 156.087 166.277 164.818 1.00 51.77  ?  104 TYR A N   1 
ATOM   751   C CA  . TYR A 1 115 ? 156.341 165.080 164.034 1.00 51.77  ?  104 TYR A CA  1 
ATOM   752   C C   . TYR A 1 115 ? 155.878 165.238 162.598 1.00 51.77  ?  104 TYR A C   1 
ATOM   753   O O   . TYR A 1 115 ? 156.433 164.591 161.704 1.00 51.77  ?  104 TYR A O   1 
ATOM   754   C CB  . TYR A 1 115 ? 155.681 163.888 164.717 1.00 51.77  ?  104 TYR A CB  1 
ATOM   755   C CG  . TYR A 1 115 ? 156.206 163.698 166.120 1.00 51.77  ?  104 TYR A CG  1 
ATOM   756   C CD1 . TYR A 1 115 ? 157.385 163.009 166.349 1.00 51.77  ?  104 TYR A CD1 1 
ATOM   757   C CD2 . TYR A 1 115 ? 155.553 164.246 167.207 1.00 51.77  ?  104 TYR A CD2 1 
ATOM   758   C CE1 . TYR A 1 115 ? 157.882 162.850 167.618 1.00 51.77  ?  104 TYR A CE1 1 
ATOM   759   C CE2 . TYR A 1 115 ? 156.044 164.095 168.481 1.00 51.77  ?  104 TYR A CE2 1 
ATOM   760   C CZ  . TYR A 1 115 ? 157.209 163.394 168.681 1.00 51.77  ?  104 TYR A CZ  1 
ATOM   761   O OH  . TYR A 1 115 ? 157.705 163.235 169.951 1.00 51.77  ?  104 TYR A OH  1 
ATOM   762   N N   . GLY A 1 116 ? 154.913 166.122 162.346 1.00 48.96  ?  105 GLY A N   1 
ATOM   763   C CA  . GLY A 1 116 ? 154.617 166.499 160.976 1.00 48.96  ?  105 GLY A CA  1 
ATOM   764   C C   . GLY A 1 116 ? 155.758 167.247 160.326 1.00 48.96  ?  105 GLY A C   1 
ATOM   765   O O   . GLY A 1 116 ? 156.010 167.087 159.130 1.00 48.96  ?  105 GLY A O   1 
ATOM   766   N N   . LEU A 1 117 ? 156.485 168.047 161.103 1.00 48.28  ?  106 LEU A N   1 
ATOM   767   C CA  . LEU A 1 117 ? 157.674 168.706 160.579 1.00 48.28  ?  106 LEU A CA  1 
ATOM   768   C C   . LEU A 1 117 ? 158.768 167.696 160.263 1.00 48.28  ?  106 LEU A C   1 
ATOM   769   O O   . LEU A 1 117 ? 159.462 167.821 159.249 1.00 48.28  ?  106 LEU A O   1 
ATOM   770   C CB  . LEU A 1 117 ? 158.171 169.745 161.578 1.00 48.28  ?  106 LEU A CB  1 
ATOM   771   C CG  . LEU A 1 117 ? 157.195 170.868 161.915 1.00 48.28  ?  106 LEU A CG  1 
ATOM   772   C CD1 . LEU A 1 117 ? 157.877 171.900 162.772 1.00 48.28  ?  106 LEU A CD1 1 
ATOM   773   C CD2 . LEU A 1 117 ? 156.675 171.493 160.649 1.00 48.28  ?  106 LEU A CD2 1 
ATOM   774   N N   . TYR A 1 118 ? 158.931 166.680 161.112 1.00 49.72  ?  107 TYR A N   1 
ATOM   775   C CA  . TYR A 1 118 ? 159.893 165.624 160.796 1.00 49.72  ?  107 TYR A CA  1 
ATOM   776   C C   . TYR A 1 118 ? 159.496 164.880 159.525 1.00 49.72  ?  107 TYR A C   1 
ATOM   777   O O   . TYR A 1 118 ? 160.357 164.511 158.710 1.00 49.72  ?  107 TYR A O   1 
ATOM   778   C CB  . TYR A 1 118 ? 160.016 164.644 161.963 1.00 49.72  ?  107 TYR A CB  1 
ATOM   779   C CG  . TYR A 1 118 ? 160.401 165.265 163.285 1.00 49.72  ?  107 TYR A CG  1 
ATOM   780   C CD1 . TYR A 1 118 ? 161.020 166.501 163.345 1.00 49.72  ?  107 TYR A CD1 1 
ATOM   781   C CD2 . TYR A 1 118 ? 160.144 164.608 164.474 1.00 49.72  ?  107 TYR A CD2 1 
ATOM   782   C CE1 . TYR A 1 118 ? 161.360 167.062 164.549 1.00 49.72  ?  107 TYR A CE1 1 
ATOM   783   C CE2 . TYR A 1 118 ? 160.486 165.161 165.678 1.00 49.72  ?  107 TYR A CE2 1 
ATOM   784   C CZ  . TYR A 1 118 ? 161.091 166.387 165.712 1.00 49.72  ?  107 TYR A CZ  1 
ATOM   785   O OH  . TYR A 1 118 ? 161.434 166.941 166.920 1.00 49.72  ?  107 TYR A OH  1 
ATOM   786   N N   . ALA A 1 119 ? 158.193 164.639 159.350 1.00 47.37  ?  108 ALA A N   1 
ATOM   787   C CA  . ALA A 1 119 ? 157.709 163.956 158.156 1.00 47.37  ?  108 ALA A CA  1 
ATOM   788   C C   . ALA A 1 119 ? 157.846 164.818 156.911 1.00 47.37  ?  108 ALA A C   1 
ATOM   789   O O   . ALA A 1 119 ? 157.936 164.288 155.800 1.00 47.37  ?  108 ALA A O   1 
ATOM   790   C CB  . ALA A 1 119 ? 156.257 163.531 158.345 1.00 47.37  ?  108 ALA A CB  1 
ATOM   791   N N   . SER A 1 120 ? 157.828 166.138 157.068 1.00 47.92  ?  109 SER A N   1 
ATOM   792   C CA  . SER A 1 120 ? 158.072 167.028 155.943 1.00 47.92  ?  109 SER A CA  1 
ATOM   793   C C   . SER A 1 120 ? 159.555 167.223 155.665 1.00 47.92  ?  109 SER A C   1 
ATOM   794   O O   . SER A 1 120 ? 159.910 167.704 154.585 1.00 47.92  ?  109 SER A O   1 
ATOM   795   C CB  . SER A 1 120 ? 157.415 168.382 156.198 1.00 47.92  ?  109 SER A CB  1 
ATOM   796   O OG  . SER A 1 120 ? 156.007 168.259 156.242 1.00 47.92  ?  109 SER A OG  1 
ATOM   797   N N   . PHE A 1 121 ? 160.421 166.885 156.618 1.00 48.01  ?  110 PHE A N   1 
ATOM   798   C CA  . PHE A 1 121 ? 161.855 167.048 156.410 1.00 48.01  ?  110 PHE A CA  1 
ATOM   799   C C   . PHE A 1 121 ? 162.525 165.811 155.819 1.00 48.01  ?  110 PHE A C   1 
ATOM   800   O O   . PHE A 1 121 ? 163.163 165.899 154.768 1.00 48.01  ?  110 PHE A O   1 
ATOM   801   C CB  . PHE A 1 121 ? 162.544 167.419 157.723 1.00 48.01  ?  110 PHE A CB  1 
ATOM   802   C CG  . PHE A 1 121 ? 164.020 167.641 157.584 1.00 48.01  ?  110 PHE A CG  1 
ATOM   803   C CD1 . PHE A 1 121 ? 164.507 168.784 156.986 1.00 48.01  ?  110 PHE A CD1 1 
ATOM   804   C CD2 . PHE A 1 121 ? 164.920 166.705 158.047 1.00 48.01  ?  110 PHE A CD2 1 
ATOM   805   C CE1 . PHE A 1 121 ? 165.859 168.988 156.857 1.00 48.01  ?  110 PHE A CE1 1 
ATOM   806   C CE2 . PHE A 1 121 ? 166.270 166.907 157.919 1.00 48.01  ?  110 PHE A CE2 1 
ATOM   807   C CZ  . PHE A 1 121 ? 166.740 168.049 157.325 1.00 48.01  ?  110 PHE A CZ  1 
ATOM   808   N N   . PHE A 1 122 ? 162.404 164.652 156.480 1.00 47.02  ?  111 PHE A N   1 
ATOM   809   C CA  . PHE A 1 122 ? 163.291 163.537 156.137 1.00 47.02  ?  111 PHE A CA  1 
ATOM   810   C C   . PHE A 1 122 ? 163.023 162.946 154.753 1.00 47.02  ?  111 PHE A C   1 
ATOM   811   O O   . PHE A 1 122 ? 163.988 162.769 153.983 1.00 47.02  ?  111 PHE A O   1 
ATOM   812   C CB  . PHE A 1 122 ? 163.232 162.466 157.230 1.00 47.02  ?  111 PHE A CB  1 
ATOM   813   C CG  . PHE A 1 122 ? 163.929 162.863 158.499 1.00 47.02  ?  111 PHE A CG  1 
ATOM   814   C CD1 . PHE A 1 122 ? 165.308 162.910 158.562 1.00 47.02  ?  111 PHE A CD1 1 
ATOM   815   C CD2 . PHE A 1 122 ? 163.204 163.189 159.628 1.00 47.02  ?  111 PHE A CD2 1 
ATOM   816   C CE1 . PHE A 1 122 ? 165.944 163.280 159.724 1.00 47.02  ?  111 PHE A CE1 1 
ATOM   817   C CE2 . PHE A 1 122 ? 163.837 163.560 160.787 1.00 47.02  ?  111 PHE A CE2 1 
ATOM   818   C CZ  . PHE A 1 122 ? 165.208 163.603 160.837 1.00 47.02  ?  111 PHE A CZ  1 
ATOM   819   N N   . PRO A 1 123 ? 161.785 162.604 154.377 1.00 46.60  ?  112 PRO A N   1 
ATOM   820   C CA  . PRO A 1 123 ? 161.576 162.004 153.050 1.00 46.60  ?  112 PRO A CA  1 
ATOM   821   C C   . PRO A 1 123 ? 162.002 162.897 151.904 1.00 46.60  ?  112 PRO A C   1 
ATOM   822   O O   . PRO A 1 123 ? 162.468 162.387 150.884 1.00 46.60  ?  112 PRO A O   1 
ATOM   823   C CB  . PRO A 1 123 ? 160.066 161.737 153.022 1.00 46.60  ?  112 PRO A CB  1 
ATOM   824   C CG  . PRO A 1 123 ? 159.665 161.674 154.430 1.00 46.60  ?  112 PRO A CG  1 
ATOM   825   C CD  . PRO A 1 123 ? 160.527 162.656 155.137 1.00 46.60  ?  112 PRO A CD  1 
ATOM   826   N N   . ALA A 1 124 ? 161.861 164.216 152.041 1.00 47.30  ?  113 ALA A N   1 
ATOM   827   C CA  . ALA A 1 124 ? 162.306 165.121 150.989 1.00 47.30  ?  113 ALA A CA  1 
ATOM   828   C C   . ALA A 1 124 ? 163.814 165.049 150.800 1.00 47.30  ?  113 ALA A C   1 
ATOM   829   O O   . ALA A 1 124 ? 164.307 165.024 149.666 1.00 47.30  ?  113 ALA A O   1 
ATOM   830   C CB  . ALA A 1 124 ? 161.876 166.548 151.316 1.00 47.30  ?  113 ALA A CB  1 
ATOM   831   N N   . ILE A 1 125 ? 164.561 164.995 151.902 1.00 48.07  ?  114 ILE A N   1 
ATOM   832   C CA  . ILE A 1 125 ? 166.015 164.953 151.815 1.00 48.07  ?  114 ILE A CA  1 
ATOM   833   C C   . ILE A 1 125 ? 166.481 163.625 151.233 1.00 48.07  ?  114 ILE A C   1 
ATOM   834   O O   . ILE A 1 125 ? 167.491 163.568 150.522 1.00 48.07  ?  114 ILE A O   1 
ATOM   835   C CB  . ILE A 1 125 ? 166.634 165.228 153.198 1.00 48.07  ?  114 ILE A CB  1 
ATOM   836   C CG1 . ILE A 1 125 ? 166.428 166.690 153.582 1.00 48.07  ?  114 ILE A CG1 1 
ATOM   837   C CG2 . ILE A 1 125 ? 168.113 164.913 153.209 1.00 48.07  ?  114 ILE A CG2 1 
ATOM   838   C CD1 . ILE A 1 125 ? 167.053 167.663 152.621 1.00 48.07  ?  114 ILE A CD1 1 
ATOM   839   N N   . ILE A 1 126 ? 165.750 162.540 151.493 1.00 47.89  ?  115 ILE A N   1 
ATOM   840   C CA  . ILE A 1 126 ? 166.157 161.264 150.901 1.00 47.89  ?  115 ILE A CA  1 
ATOM   841   C C   . ILE A 1 126 ? 165.789 161.211 149.420 1.00 47.89  ?  115 ILE A C   1 
ATOM   842   O O   . ILE A 1 126 ? 166.570 160.735 148.585 1.00 47.89  ?  115 ILE A O   1 
ATOM   843   C CB  . ILE A 1 126 ? 165.555 160.083 151.683 1.00 47.89  ?  115 ILE A CB  1 
ATOM   844   C CG1 . ILE A 1 126 ? 166.555 159.557 152.710 1.00 47.89  ?  115 ILE A CG1 1 
ATOM   845   C CG2 . ILE A 1 126 ? 165.196 158.958 150.740 1.00 47.89  ?  115 ILE A CG2 1 
ATOM   846   C CD1 . ILE A 1 126 ? 166.994 160.567 153.728 1.00 47.89  ?  115 ILE A CD1 1 
ATOM   847   N N   . TYR A 1 127 ? 164.603 161.708 149.066 1.00 47.56  ?  116 TYR A N   1 
ATOM   848   C CA  . TYR A 1 127 ? 164.180 161.701 147.673 1.00 47.56  ?  116 TYR A CA  1 
ATOM   849   C C   . TYR A 1 127 ? 165.022 162.638 146.820 1.00 47.56  ?  116 TYR A C   1 
ATOM   850   O O   . TYR A 1 127 ? 165.097 162.458 145.603 1.00 47.56  ?  116 TYR A O   1 
ATOM   851   C CB  . TYR A 1 127 ? 162.708 162.082 147.580 1.00 47.56  ?  116 TYR A CB  1 
ATOM   852   C CG  . TYR A 1 127 ? 162.061 161.718 146.274 1.00 47.56  ?  116 TYR A CG  1 
ATOM   853   C CD1 . TYR A 1 127 ? 161.422 160.504 146.115 1.00 47.56  ?  116 TYR A CD1 1 
ATOM   854   C CD2 . TYR A 1 127 ? 162.076 162.596 145.205 1.00 47.56  ?  116 TYR A CD2 1 
ATOM   855   C CE1 . TYR A 1 127 ? 160.833 160.169 144.929 1.00 47.56  ?  116 TYR A CE1 1 
ATOM   856   C CE2 . TYR A 1 127 ? 161.489 162.270 144.017 1.00 47.56  ?  116 TYR A CE2 1 
ATOM   857   C CZ  . TYR A 1 127 ? 160.869 161.057 143.886 1.00 47.56  ?  116 TYR A CZ  1 
ATOM   858   O OH  . TYR A 1 127 ? 160.273 160.728 142.699 1.00 47.56  ?  116 TYR A OH  1 
ATOM   859   N N   . LEU A 1 128 ? 165.641 163.650 147.429 1.00 50.80  ?  117 LEU A N   1 
ATOM   860   C CA  . LEU A 1 128 ? 166.596 164.467 146.689 1.00 50.80  ?  117 LEU A CA  1 
ATOM   861   C C   . LEU A 1 128 ? 167.711 163.617 146.101 1.00 50.80  ?  117 LEU A C   1 
ATOM   862   O O   . LEU A 1 128 ? 168.200 163.903 145.003 1.00 50.80  ?  117 LEU A O   1 
ATOM   863   C CB  . LEU A 1 128 ? 167.178 165.546 147.598 1.00 50.80  ?  117 LEU A CB  1 
ATOM   864   C CG  . LEU A 1 128 ? 168.421 166.274 147.098 1.00 50.80  ?  117 LEU A CG  1 
ATOM   865   C CD1 . LEU A 1 128 ? 168.039 167.374 146.133 1.00 50.80  ?  117 LEU A CD1 1 
ATOM   866   C CD2 . LEU A 1 128 ? 169.201 166.832 148.263 1.00 50.80  ?  117 LEU A CD2 1 
ATOM   867   N N   . PHE A 1 129 ? 168.112 162.559 146.801 1.00 52.44  ?  118 PHE A N   1 
ATOM   868   C CA  . PHE A 1 129 ? 169.205 161.702 146.367 1.00 52.44  ?  118 PHE A CA  1 
ATOM   869   C C   . PHE A 1 129 ? 168.733 160.511 145.547 1.00 52.44  ?  118 PHE A C   1 
ATOM   870   O O   . PHE A 1 129 ? 169.395 160.134 144.575 1.00 52.44  ?  118 PHE A O   1 
ATOM   871   C CB  . PHE A 1 129 ? 169.992 161.203 147.580 1.00 52.44  ?  118 PHE A CB  1 
ATOM   872   C CG  . PHE A 1 129 ? 170.849 162.249 148.212 1.00 52.44  ?  118 PHE A CG  1 
ATOM   873   C CD1 . PHE A 1 129 ? 172.049 162.611 147.640 1.00 52.44  ?  118 PHE A CD1 1 
ATOM   874   C CD2 . PHE A 1 129 ? 170.456 162.870 149.378 1.00 52.44  ?  118 PHE A CD2 1 
ATOM   875   C CE1 . PHE A 1 129 ? 172.839 163.575 148.215 1.00 52.44  ?  118 PHE A CE1 1 
ATOM   876   C CE2 . PHE A 1 129 ? 171.245 163.835 149.958 1.00 52.44  ?  118 PHE A CE2 1 
ATOM   877   C CZ  . PHE A 1 129 ? 172.437 164.187 149.376 1.00 52.44  ?  118 PHE A CZ  1 
ATOM   878   N N   . PHE A 1 130 ? 167.607 159.901 145.909 1.00 52.94  ?  119 PHE A N   1 
ATOM   879   C CA  . PHE A 1 130 ? 167.202 158.647 145.289 1.00 52.94  ?  119 PHE A CA  1 
ATOM   880   C C   . PHE A 1 130 ? 165.977 158.759 144.393 1.00 52.94  ?  119 PHE A C   1 
ATOM   881   O O   . PHE A 1 130 ? 165.499 157.733 143.905 1.00 52.94  ?  119 PHE A O   1 
ATOM   882   C CB  . PHE A 1 130 ? 166.945 157.590 146.367 1.00 52.94  ?  119 PHE A CB  1 
ATOM   883   C CG  . PHE A 1 130 ? 168.148 157.275 147.200 1.00 52.94  ?  119 PHE A CG  1 
ATOM   884   C CD1 . PHE A 1 130 ? 169.077 156.348 146.775 1.00 52.94  ?  119 PHE A CD1 1 
ATOM   885   C CD2 . PHE A 1 130 ? 168.354 157.913 148.407 1.00 52.94  ?  119 PHE A CD2 1 
ATOM   886   C CE1 . PHE A 1 130 ? 170.182 156.062 147.536 1.00 52.94  ?  119 PHE A CE1 1 
ATOM   887   C CE2 . PHE A 1 130 ? 169.459 157.629 149.172 1.00 52.94  ?  119 PHE A CE2 1 
ATOM   888   C CZ  . PHE A 1 130 ? 170.375 156.703 148.736 1.00 52.94  ?  119 PHE A CZ  1 
ATOM   889   N N   . GLY A 1 131 ? 165.464 159.955 144.141 1.00 51.30  ?  120 GLY A N   1 
ATOM   890   C CA  . GLY A 1 131 ? 164.233 160.119 143.396 1.00 51.30  ?  120 GLY A CA  1 
ATOM   891   C C   . GLY A 1 131 ? 164.459 160.439 141.932 1.00 51.30  ?  120 GLY A C   1 
ATOM   892   O O   . GLY A 1 131 ? 165.403 161.135 141.574 1.00 51.30  ?  120 GLY A O   1 
ATOM   893   N N   . THR A 1 132 ? 163.530 160.039 141.101 1.00 52.70  ?  121 THR A N   1 
ATOM   894   C CA  . THR A 1 132 ? 163.654 160.246 139.673 1.00 52.70  ?  121 THR A CA  1 
ATOM   895   C C   . THR A 1 132 ? 162.777 161.359 139.201 1.00 52.70  ?  121 THR A C   1 
ATOM   896   O O   . THR A 1 132 ? 163.030 161.952 138.183 1.00 52.70  ?  121 THR A O   1 
ATOM   897   C CB  . THR A 1 132 ? 163.448 158.962 138.845 1.00 52.70  ?  121 THR A CB  1 
ATOM   898   O OG1 . THR A 1 132 ? 162.122 158.480 139.014 1.00 52.70  ?  121 THR A OG1 1 
ATOM   899   C CG2 . THR A 1 132 ? 164.402 157.927 139.290 1.00 52.70  ?  121 THR A CG2 1 
ATOM   900   N N   . SER A 1 133 ? 161.794 161.744 139.998 1.00 51.67  ?  122 SER A N   1 
ATOM   901   C CA  . SER A 1 133 ? 160.967 162.879 139.630 1.00 51.67  ?  122 SER A CA  1 
ATOM   902   C C   . SER A 1 133 ? 161.714 164.182 139.876 1.00 51.67  ?  122 SER A C   1 
ATOM   903   O O   . SER A 1 133 ? 162.745 164.225 140.550 1.00 51.67  ?  122 SER A O   1 
ATOM   904   C CB  . SER A 1 133 ? 159.661 162.878 140.416 1.00 51.67  ?  122 SER A CB  1 
ATOM   905   O OG  . SER A 1 133 ? 158.680 163.646 139.751 1.00 51.67  ?  122 SER A OG  1 
ATOM   906   N N   . ARG A 1 134 ? 161.179 165.257 139.306 1.00 53.95  ?  123 ARG A N   1 
ATOM   907   C CA  . ARG A 1 134 ? 161.769 166.578 139.434 1.00 53.95  ?  123 ARG A CA  1 
ATOM   908   C C   . ARG A 1 134 ? 160.772 167.638 139.861 1.00 53.95  ?  123 ARG A C   1 
ATOM   909   O O   . ARG A 1 134 ? 161.156 168.802 140.005 1.00 53.95  ?  123 ARG A O   1 
ATOM   910   C CB  . ARG A 1 134 ? 162.409 167.009 138.110 1.00 53.95  ?  123 ARG A CB  1 
ATOM   911   C CG  . ARG A 1 134 ? 163.297 165.969 137.470 1.00 53.95  ?  123 ARG A CG  1 
ATOM   912   C CD  . ARG A 1 134 ? 164.062 166.554 136.309 1.00 53.95  ?  123 ARG A CD  1 
ATOM   913   N NE  . ARG A 1 134 ? 163.470 167.809 135.860 1.00 53.95  ?  123 ARG A NE  1 
ATOM   914   C CZ  . ARG A 1 134 ? 163.715 168.369 134.681 1.00 53.95  ?  123 ARG A CZ  1 
ATOM   915   N NH1 . ARG A 1 134 ? 163.130 169.512 134.353 1.00 53.95  1  123 ARG A NH1 1 
ATOM   916   N NH2 . ARG A 1 134 ? 164.539 167.781 133.827 1.00 53.95  ?  123 ARG A NH2 1 
ATOM   917   N N   . HIS A 1 135 ? 159.509 167.278 140.071 1.00 52.14  ?  124 HIS A N   1 
ATOM   918   C CA  . HIS A 1 135 ? 158.473 168.277 140.285 1.00 52.14  ?  124 HIS A CA  1 
ATOM   919   C C   . HIS A 1 135 ? 157.550 167.984 141.454 1.00 52.14  ?  124 HIS A C   1 
ATOM   920   O O   . HIS A 1 135 ? 156.761 168.861 141.816 1.00 52.14  ?  124 HIS A O   1 
ATOM   921   C CB  . HIS A 1 135 ? 157.629 168.442 139.011 1.00 52.14  ?  124 HIS A CB  1 
ATOM   922   C CG  . HIS A 1 135 ? 158.362 169.087 137.880 1.00 52.14  ?  124 HIS A CG  1 
ATOM   923   N ND1 . HIS A 1 135 ? 158.978 168.361 136.884 1.00 52.14  ?  124 HIS A ND1 1 
ATOM   924   C CD2 . HIS A 1 135 ? 158.589 170.388 137.591 1.00 52.14  ?  124 HIS A CD2 1 
ATOM   925   C CE1 . HIS A 1 135 ? 159.551 169.190 136.031 1.00 52.14  ?  124 HIS A CE1 1 
ATOM   926   N NE2 . HIS A 1 135 ? 159.330 170.425 136.438 1.00 52.14  ?  124 HIS A NE2 1 
ATOM   927   N N   . ILE A 1 136 ? 157.606 166.808 142.049 1.00 49.05  ?  125 ILE A N   1 
ATOM   928   C CA  . ILE A 1 136 ? 156.719 166.473 143.153 1.00 49.05  ?  125 ILE A CA  1 
ATOM   929   C C   . ILE A 1 136 ? 157.345 166.926 144.461 1.00 49.05  ?  125 ILE A C   1 
ATOM   930   O O   . ILE A 1 136 ? 158.570 166.936 144.615 1.00 49.05  ?  125 ILE A O   1 
ATOM   931   C CB  . ILE A 1 136 ? 156.401 164.967 143.177 1.00 49.05  ?  125 ILE A CB  1 
ATOM   932   C CG1 . ILE A 1 136 ? 157.631 164.151 143.570 1.00 49.05  ?  125 ILE A CG1 1 
ATOM   933   C CG2 . ILE A 1 136 ? 155.850 164.526 141.844 1.00 49.05  ?  125 ILE A CG2 1 
ATOM   934   C CD1 . ILE A 1 136 ? 157.294 162.837 144.219 1.00 49.05  ?  125 ILE A CD1 1 
ATOM   935   N N   . SER A 1 137 ? 156.494 167.327 145.399 1.00 48.94  ?  126 SER A N   1 
ATOM   936   C CA  . SER A 1 137 ? 156.909 167.696 146.744 1.00 48.94  ?  126 SER A CA  1 
ATOM   937   C C   . SER A 1 137 ? 156.698 166.494 147.651 1.00 48.94  ?  126 SER A C   1 
ATOM   938   O O   . SER A 1 137 ? 155.567 166.029 147.812 1.00 48.94  ?  126 SER A O   1 
ATOM   939   C CB  . SER A 1 137 ? 156.118 168.900 147.246 1.00 48.94  ?  126 SER A CB  1 
ATOM   940   O OG  . SER A 1 137 ? 156.864 169.632 148.200 1.00 48.94  ?  126 SER A OG  1 
ATOM   941   N N   . VAL A 1 138 ? 157.778 165.992 148.232 1.00 48.24  ?  127 VAL A N   1 
ATOM   942   C CA  . VAL A 1 138 ? 157.739 164.756 149.001 1.00 48.24  ?  127 VAL A CA  1 
ATOM   943   C C   . VAL A 1 138 ? 157.420 165.081 150.452 1.00 48.24  ?  127 VAL A C   1 
ATOM   944   O O   . VAL A 1 138 ? 158.046 165.956 151.059 1.00 48.24  ?  127 VAL A O   1 
ATOM   945   C CB  . VAL A 1 138 ? 159.066 163.991 148.880 1.00 48.24  ?  127 VAL A CB  1 
ATOM   946   C CG1 . VAL A 1 138 ? 158.879 162.551 149.290 1.00 48.24  ?  127 VAL A CG1 1 
ATOM   947   C CG2 . VAL A 1 138 ? 159.586 164.072 147.464 1.00 48.24  ?  127 VAL A CG2 1 
ATOM   948   N N   . GLY A 1 139 ? 156.450 164.369 151.008 1.00 47.84  ?  128 GLY A N   1 
ATOM   949   C CA  . GLY A 1 139 ? 155.960 164.628 152.335 1.00 47.84  ?  128 GLY A CA  1 
ATOM   950   C C   . GLY A 1 139 ? 154.597 164.000 152.528 1.00 47.84  ?  128 GLY A C   1 
ATOM   951   O O   . GLY A 1 139 ? 154.114 163.248 151.679 1.00 47.84  ?  128 GLY A O   1 
ATOM   952   N N   . PRO A 1 140 ? 153.945 164.303 153.643 1.00 46.70  ?  129 PRO A N   1 
ATOM   953   C CA  . PRO A 1 140 ? 152.652 163.688 153.942 1.00 46.70  ?  129 PRO A CA  1 
ATOM   954   C C   . PRO A 1 140 ? 151.502 164.358 153.200 1.00 46.70  ?  129 PRO A C   1 
ATOM   955   O O   . PRO A 1 140 ? 151.569 165.522 152.805 1.00 46.70  ?  129 PRO A O   1 
ATOM   956   C CB  . PRO A 1 140 ? 152.523 163.898 155.456 1.00 46.70  ?  129 PRO A CB  1 
ATOM   957   C CG  . PRO A 1 140 ? 153.281 165.151 155.715 1.00 46.70  ?  129 PRO A CG  1 
ATOM   958   C CD  . PRO A 1 140 ? 154.364 165.253 154.685 1.00 46.70  ?  129 PRO A CD  1 
ATOM   959   N N   . PHE A 1 141 ? 150.443 163.588 153.005 1.00 45.54  ?  130 PHE A N   1 
ATOM   960   C CA  . PHE A 1 141 ? 149.205 164.087 152.431 1.00 45.54  ?  130 PHE A CA  1 
ATOM   961   C C   . PHE A 1 141 ? 148.051 163.573 153.279 1.00 45.54  ?  130 PHE A C   1 
ATOM   962   O O   . PHE A 1 141 ? 148.218 162.615 154.039 1.00 45.54  ?  130 PHE A O   1 
ATOM   963   C CB  . PHE A 1 141 ? 149.054 163.689 150.953 1.00 45.54  ?  130 PHE A CB  1 
ATOM   964   C CG  . PHE A 1 141 ? 149.161 162.219 150.678 1.00 45.54  ?  130 PHE A CG  1 
ATOM   965   C CD1 . PHE A 1 141 ? 148.033 161.478 150.392 1.00 45.54  ?  130 PHE A CD1 1 
ATOM   966   C CD2 . PHE A 1 141 ? 150.389 161.587 150.649 1.00 45.54  ?  130 PHE A CD2 1 
ATOM   967   C CE1 . PHE A 1 141 ? 148.124 160.135 150.118 1.00 45.54  ?  130 PHE A CE1 1 
ATOM   968   C CE2 . PHE A 1 141 ? 150.484 160.244 150.375 1.00 45.54  ?  130 PHE A CE2 1 
ATOM   969   C CZ  . PHE A 1 141 ? 149.351 159.519 150.108 1.00 45.54  ?  130 PHE A CZ  1 
ATOM   970   N N   . PRO A 1 142 ? 146.874 164.213 153.199 1.00 45.22  ?  131 PRO A N   1 
ATOM   971   C CA  . PRO A 1 142 ? 145.819 163.911 154.185 1.00 45.22  ?  131 PRO A CA  1 
ATOM   972   C C   . PRO A 1 142 ? 145.381 162.459 154.215 1.00 45.22  ?  131 PRO A C   1 
ATOM   973   O O   . PRO A 1 142 ? 145.133 161.917 155.300 1.00 45.22  ?  131 PRO A O   1 
ATOM   974   C CB  . PRO A 1 142 ? 144.672 164.833 153.752 1.00 45.22  ?  131 PRO A CB  1 
ATOM   975   C CG  . PRO A 1 142 ? 145.315 165.910 152.993 1.00 45.22  ?  131 PRO A CG  1 
ATOM   976   C CD  . PRO A 1 142 ? 146.457 165.287 152.283 1.00 45.22  ?  131 PRO A CD  1 
ATOM   977   N N   . ILE A 1 143 ? 145.273 161.810 153.056 1.00 46.92  ?  132 ILE A N   1 
ATOM   978   C CA  . ILE A 1 143 ? 144.789 160.435 153.021 1.00 46.92  ?  132 ILE A CA  1 
ATOM   979   C C   . ILE A 1 143 ? 145.763 159.507 153.731 1.00 46.92  ?  132 ILE A C   1 
ATOM   980   O O   . ILE A 1 143 ? 145.357 158.622 154.493 1.00 46.92  ?  132 ILE A O   1 
ATOM   981   C CB  . ILE A 1 143 ? 144.539 159.994 151.570 1.00 46.92  ?  132 ILE A CB  1 
ATOM   982   C CG1 . ILE A 1 143 ? 143.526 160.923 150.902 1.00 46.92  ?  132 ILE A CG1 1 
ATOM   983   C CG2 . ILE A 1 143 ? 144.063 158.555 151.527 1.00 46.92  ?  132 ILE A CG2 1 
ATOM   984   C CD1 . ILE A 1 143 ? 143.221 160.553 149.476 1.00 46.92  ?  132 ILE A CD1 1 
ATOM   985   N N   . LEU A 1 144 ? 147.064 159.707 153.519 1.00 45.14  ?  133 LEU A N   1 
ATOM   986   C CA  . LEU A 1 144 ? 148.032 158.827 154.161 1.00 45.14  ?  133 LEU A CA  1 
ATOM   987   C C   . LEU A 1 144 ? 148.160 159.120 155.645 1.00 45.14  ?  133 LEU A C   1 
ATOM   988   O O   . LEU A 1 144 ? 148.399 158.202 156.428 1.00 45.14  ?  133 LEU A O   1 
ATOM   989   C CB  . LEU A 1 144 ? 149.397 158.937 153.494 1.00 45.14  ?  133 LEU A CB  1 
ATOM   990   C CG  . LEU A 1 144 ? 150.130 157.600 153.458 1.00 45.14  ?  133 LEU A CG  1 
ATOM   991   C CD1 . LEU A 1 144 ? 149.393 156.632 152.560 1.00 45.14  ?  133 LEU A CD1 1 
ATOM   992   C CD2 . LEU A 1 144 ? 151.550 157.783 152.997 1.00 45.14  ?  133 LEU A CD2 1 
ATOM   993   N N   . SER A 1 145 ? 148.012 160.379 156.055 1.00 45.59  ?  134 SER A N   1 
ATOM   994   C CA  . SER A 1 145 ? 148.002 160.675 157.482 1.00 45.59  ?  134 SER A CA  1 
ATOM   995   C C   . SER A 1 145 ? 146.804 160.030 158.158 1.00 45.59  ?  134 SER A C   1 
ATOM   996   O O   . SER A 1 145 ? 146.919 159.513 159.273 1.00 45.59  ?  134 SER A O   1 
ATOM   997   C CB  . SER A 1 145 ? 148.000 162.182 157.705 1.00 45.59  ?  134 SER A CB  1 
ATOM   998   O OG  . SER A 1 145 ? 148.761 162.834 156.711 1.00 45.59  ?  134 SER A OG  1 
ATOM   999   N N   . MET A 1 146 ? 145.650 160.027 157.490 1.00 46.68  ?  135 MET A N   1 
ATOM   1000  C CA  . MET A 1 146 ? 144.484 159.345 158.039 1.00 46.68  ?  135 MET A CA  1 
ATOM   1001  C C   . MET A 1 146 ? 144.713 157.844 158.140 1.00 46.68  ?  135 MET A C   1 
ATOM   1002  O O   . MET A 1 146 ? 144.375 157.223 159.156 1.00 46.68  ?  135 MET A O   1 
ATOM   1003  C CB  . MET A 1 146 ? 143.258 159.643 157.183 1.00 46.68  ?  135 MET A CB  1 
ATOM   1004  C CG  . MET A 1 146 ? 142.598 160.964 157.498 1.00 46.68  ?  135 MET A CG  1 
ATOM   1005  S SD  . MET A 1 146 ? 140.827 160.885 157.256 1.00 46.68  ?  135 MET A SD  1 
ATOM   1006  C CE  . MET A 1 146 ? 140.438 159.393 158.154 1.00 46.68  ?  135 MET A CE  1 
ATOM   1007  N N   . MET A 1 147 ? 145.287 157.241 157.096 1.00 46.96  ?  136 MET A N   1 
ATOM   1008  C CA  . MET A 1 147 ? 145.568 155.809 157.129 1.00 46.96  ?  136 MET A CA  1 
ATOM   1009  C C   . MET A 1 147 ? 146.579 155.460 158.217 1.00 46.96  ?  136 MET A C   1 
ATOM   1010  O O   . MET A 1 147 ? 146.430 154.449 158.916 1.00 46.96  ?  136 MET A O   1 
ATOM   1011  C CB  . MET A 1 147 ? 146.068 155.348 155.763 1.00 46.96  ?  136 MET A CB  1 
ATOM   1012  C CG  . MET A 1 147 ? 145.043 155.486 154.664 1.00 46.96  ?  136 MET A CG  1 
ATOM   1013  S SD  . MET A 1 147 ? 145.590 154.799 153.101 1.00 46.96  ?  136 MET A SD  1 
ATOM   1014  C CE  . MET A 1 147 ? 145.834 153.098 153.567 1.00 46.96  ?  136 MET A CE  1 
ATOM   1015  N N   . VAL A 1 148 ? 147.611 156.286 158.381 1.00 47.97  ?  137 VAL A N   1 
ATOM   1016  C CA  . VAL A 1 148 ? 148.612 156.045 159.412 1.00 47.97  ?  137 VAL A CA  1 
ATOM   1017  C C   . VAL A 1 148 ? 148.001 156.203 160.796 1.00 47.97  ?  137 VAL A C   1 
ATOM   1018  O O   . VAL A 1 148 ? 148.309 155.435 161.709 1.00 47.97  ?  137 VAL A O   1 
ATOM   1019  C CB  . VAL A 1 148 ? 149.820 156.976 159.209 1.00 47.97  ?  137 VAL A CB  1 
ATOM   1020  C CG1 . VAL A 1 148 ? 150.717 156.969 160.432 1.00 47.97  ?  137 VAL A CG1 1 
ATOM   1021  C CG2 . VAL A 1 148 ? 150.608 156.562 157.984 1.00 47.97  ?  137 VAL A CG2 1 
ATOM   1022  N N   . GLY A 1 149 ? 147.118 157.184 160.974 1.00 48.60  ?  138 GLY A N   1 
ATOM   1023  C CA  . GLY A 1 149 ? 146.475 157.352 162.265 1.00 48.60  ?  138 GLY A CA  1 
ATOM   1024  C C   . GLY A 1 149 ? 145.561 156.195 162.615 1.00 48.60  ?  138 GLY A C   1 
ATOM   1025  O O   . GLY A 1 149 ? 145.504 155.764 163.769 1.00 48.60  ?  138 GLY A O   1 
ATOM   1026  N N   . LEU A 1 150 ? 144.839 155.671 161.624 1.00 50.12  ?  139 LEU A N   1 
ATOM   1027  C CA  . LEU A 1 150 ? 144.008 154.496 161.869 1.00 50.12  ?  139 LEU A CA  1 
ATOM   1028  C C   . LEU A 1 150 ? 144.857 153.272 162.192 1.00 50.12  ?  139 LEU A C   1 
ATOM   1029  O O   . LEU A 1 150 ? 144.516 152.491 163.090 1.00 50.12  ?  139 LEU A O   1 
ATOM   1030  C CB  . LEU A 1 150 ? 143.117 154.230 160.660 1.00 50.12  ?  139 LEU A CB  1 
ATOM   1031  C CG  . LEU A 1 150 ? 141.891 155.133 160.539 1.00 50.12  ?  139 LEU A CG  1 
ATOM   1032  C CD1 . LEU A 1 150 ? 141.436 155.230 159.097 1.00 50.12  ?  139 LEU A CD1 1 
ATOM   1033  C CD2 . LEU A 1 150 ? 140.770 154.629 161.425 1.00 50.12  ?  139 LEU A CD2 1 
ATOM   1034  N N   . ALA A 1 151 ? 145.974 153.093 161.484 1.00 49.94  ?  140 ALA A N   1 
ATOM   1035  C CA  . ALA A 1 151 ? 146.866 151.981 161.790 1.00 49.94  ?  140 ALA A CA  1 
ATOM   1036  C C   . ALA A 1 151 ? 147.456 152.113 163.189 1.00 49.94  ?  140 ALA A C   1 
ATOM   1037  O O   . ALA A 1 151 ? 147.599 151.118 163.906 1.00 49.94  ?  140 ALA A O   1 
ATOM   1038  C CB  . ALA A 1 151 ? 147.974 151.897 160.743 1.00 49.94  ?  140 ALA A CB  1 
ATOM   1039  N N   . VAL A 1 152 ? 147.796 153.335 163.599 1.00 52.49  ?  141 VAL A N   1 
ATOM   1040  C CA  . VAL A 1 152 ? 148.300 153.558 164.950 1.00 52.49  ?  141 VAL A CA  1 
ATOM   1041  C C   . VAL A 1 152 ? 147.244 153.283 166.006 1.00 52.49  ?  141 VAL A C   1 
ATOM   1042  O O   . VAL A 1 152 ? 147.560 152.690 167.041 1.00 52.49  ?  141 VAL A O   1 
ATOM   1043  C CB  . VAL A 1 152 ? 148.824 154.992 165.114 1.00 52.49  ?  141 VAL A CB  1 
ATOM   1044  C CG1 . VAL A 1 152 ? 149.179 155.268 166.558 1.00 52.49  ?  141 VAL A CG1 1 
ATOM   1045  C CG2 . VAL A 1 152 ? 150.017 155.209 164.241 1.00 52.49  ?  141 VAL A CG2 1 
ATOM   1046  N N   . SER A 1 153 ? 145.999 153.703 165.783 1.00 55.87  ?  142 SER A N   1 
ATOM   1047  C CA  . SER A 1 153 ? 144.955 153.400 166.752 1.00 55.87  ?  142 SER A CA  1 
ATOM   1048  C C   . SER A 1 153 ? 144.727 151.900 166.865 1.00 55.87  ?  142 SER A C   1 
ATOM   1049  O O   . SER A 1 153 ? 144.575 151.383 167.975 1.00 55.87  ?  142 SER A O   1 
ATOM   1050  C CB  . SER A 1 153 ? 143.659 154.118 166.383 1.00 55.87  ?  142 SER A CB  1 
ATOM   1051  O OG  . SER A 1 153 ? 142.979 153.440 165.344 1.00 55.87  ?  142 SER A OG  1 
ATOM   1052  N N   . GLY A 1 154 ? 144.745 151.182 165.744 1.00 57.71  ?  143 GLY A N   1 
ATOM   1053  C CA  . GLY A 1 154 ? 144.661 149.734 165.783 1.00 57.71  ?  143 GLY A CA  1 
ATOM   1054  C C   . GLY A 1 154 ? 145.819 149.077 166.508 1.00 57.71  ?  143 GLY A C   1 
ATOM   1055  O O   . GLY A 1 154 ? 145.632 148.093 167.229 1.00 57.71  ?  143 GLY A O   1 
ATOM   1056  N N   . ALA A 1 155 ? 147.026 149.615 166.330 1.00 59.46  ?  144 ALA A N   1 
ATOM   1057  C CA  . ALA A 1 155 ? 148.196 149.043 166.987 1.00 59.46  ?  144 ALA A CA  1 
ATOM   1058  C C   . ALA A 1 155 ? 148.151 149.269 168.492 1.00 59.46  ?  144 ALA A C   1 
ATOM   1059  O O   . ALA A 1 155 ? 148.451 148.362 169.274 1.00 59.46  ?  144 ALA A O   1 
ATOM   1060  C CB  . ALA A 1 155 ? 149.473 149.635 166.390 1.00 59.46  ?  144 ALA A CB  1 
ATOM   1061  N N   . VAL A 1 156 ? 147.787 150.479 168.919 1.00 61.29  ?  145 VAL A N   1 
ATOM   1062  C CA  . VAL A 1 156 ? 147.676 150.755 170.350 1.00 61.29  ?  145 VAL A CA  1 
ATOM   1063  C C   . VAL A 1 156 ? 146.523 149.966 170.957 1.00 61.29  ?  145 VAL A C   1 
ATOM   1064  O O   . VAL A 1 156 ? 146.558 149.599 172.138 1.00 61.29  ?  145 VAL A O   1 
ATOM   1065  C CB  . VAL A 1 156 ? 147.530 152.266 170.605 1.00 61.29  ?  145 VAL A CB  1 
ATOM   1066  C CG1 . VAL A 1 156 ? 147.631 152.560 172.085 1.00 61.29  ?  145 VAL A CG1 1 
ATOM   1067  C CG2 . VAL A 1 156 ? 148.618 153.023 169.883 1.00 61.29  ?  145 VAL A CG2 1 
ATOM   1068  N N   . SER A 1 157 ? 145.486 149.688 170.166 1.00 63.07  ?  146 SER A N   1 
ATOM   1069  C CA  . SER A 1 157 ? 144.416 148.824 170.647 1.00 63.07  ?  146 SER A CA  1 
ATOM   1070  C C   . SER A 1 157 ? 144.917 147.404 170.878 1.00 63.07  ?  146 SER A C   1 
ATOM   1071  O O   . SER A 1 157 ? 144.738 146.846 171.965 1.00 63.07  ?  146 SER A O   1 
ATOM   1072  C CB  . SER A 1 157 ? 143.256 148.829 169.653 1.00 63.07  ?  146 SER A CB  1 
ATOM   1073  O OG  . SER A 1 157 ? 142.223 147.961 170.075 1.00 63.07  ?  146 SER A OG  1 
ATOM   1074  N N   . LYS A 1 158 ? 145.560 146.809 169.872 1.00 64.18  ?  147 LYS A N   1 
ATOM   1075  C CA  . LYS A 1 158 ? 145.990 145.418 169.956 1.00 64.18  ?  147 LYS A CA  1 
ATOM   1076  C C   . LYS A 1 158 ? 147.253 145.213 170.783 1.00 64.18  ?  147 LYS A C   1 
ATOM   1077  O O   . LYS A 1 158 ? 147.714 144.075 170.894 1.00 64.18  ?  147 LYS A O   1 
ATOM   1078  C CB  . LYS A 1 158 ? 146.220 144.852 168.557 1.00 64.18  ?  147 LYS A CB  1 
ATOM   1079  C CG  . LYS A 1 158 ? 144.984 144.814 167.687 1.00 64.18  ?  147 LYS A CG  1 
ATOM   1080  C CD  . LYS A 1 158 ? 145.357 144.606 166.233 1.00 64.18  ?  147 LYS A CD  1 
ATOM   1081  C CE  . LYS A 1 158 ? 144.197 144.935 165.313 1.00 64.18  ?  147 LYS A CE  1 
ATOM   1082  N NZ  . LYS A 1 158 ? 144.627 144.982 163.890 1.00 64.18  1  147 LYS A NZ  1 
ATOM   1083  N N   . ALA A 1 159 ? 147.827 146.267 171.358 1.00 68.31  ?  148 ALA A N   1 
ATOM   1084  C CA  . ALA A 1 159 ? 149.072 146.117 172.099 1.00 68.31  ?  148 ALA A CA  1 
ATOM   1085  C C   . ALA A 1 159 ? 148.824 145.427 173.433 1.00 68.31  ?  148 ALA A C   1 
ATOM   1086  O O   . ALA A 1 159 ? 147.935 145.817 174.194 1.00 68.31  ?  148 ALA A O   1 
ATOM   1087  C CB  . ALA A 1 159 ? 149.726 147.478 172.324 1.00 68.31  ?  148 ALA A CB  1 
ATOM   1088  N N   . VAL A 1 160 ? 149.619 144.399 173.715 1.00 74.82  ?  149 VAL A N   1 
ATOM   1089  C CA  . VAL A 1 160 ? 149.512 143.634 174.955 1.00 74.82  ?  149 VAL A CA  1 
ATOM   1090  C C   . VAL A 1 160 ? 149.886 144.547 176.118 1.00 74.82  ?  149 VAL A C   1 
ATOM   1091  O O   . VAL A 1 160 ? 150.808 145.365 175.992 1.00 74.82  ?  149 VAL A O   1 
ATOM   1092  C CB  . VAL A 1 160 ? 150.386 142.366 174.896 1.00 74.82  ?  149 VAL A CB  1 
ATOM   1093  C CG1 . VAL A 1 160 ? 151.867 142.698 175.021 1.00 74.82  ?  149 VAL A CG1 1 
ATOM   1094  C CG2 . VAL A 1 160 ? 149.965 141.365 175.958 1.00 74.82  ?  149 VAL A CG2 1 
ATOM   1095  N N   . PRO A 1 161 ? 149.171 144.485 177.251 1.00 75.65  ?  150 PRO A N   1 
ATOM   1096  C CA  . PRO A 1 161 ? 149.503 145.339 178.397 1.00 75.65  ?  150 PRO A CA  1 
ATOM   1097  C C   . PRO A 1 161 ? 150.822 144.952 179.056 1.00 75.65  ?  150 PRO A C   1 
ATOM   1098  O O   . PRO A 1 161 ? 151.281 143.830 178.855 1.00 75.65  ?  150 PRO A O   1 
ATOM   1099  C CB  . PRO A 1 161 ? 148.329 145.116 179.357 1.00 75.65  ?  150 PRO A CB  1 
ATOM   1100  C CG  . PRO A 1 161 ? 147.226 144.582 178.506 1.00 75.65  ?  150 PRO A CG  1 
ATOM   1101  C CD  . PRO A 1 161 ? 147.901 143.768 177.453 1.00 75.65  ?  150 PRO A CD  1 
ATOM   1102  N N   . LEU A 1 179 ? 148.663 161.889 180.388 1.00 81.54  ?  168 LEU A N   1 
ATOM   1103  C CA  . LEU A 1 179 ? 148.202 161.833 179.005 1.00 81.54  ?  168 LEU A CA  1 
ATOM   1104  C C   . LEU A 1 179 ? 149.369 161.759 178.029 1.00 81.54  ?  168 LEU A C   1 
ATOM   1105  O O   . LEU A 1 179 ? 149.219 161.279 176.909 1.00 81.54  ?  168 LEU A O   1 
ATOM   1106  C CB  . LEU A 1 179 ? 147.331 163.048 178.676 1.00 81.54  ?  168 LEU A CB  1 
ATOM   1107  C CG  . LEU A 1 179 ? 146.010 163.186 179.432 1.00 81.54  ?  168 LEU A CG  1 
ATOM   1108  C CD1 . LEU A 1 179 ? 145.569 164.640 179.474 1.00 81.54  ?  168 LEU A CD1 1 
ATOM   1109  C CD2 . LEU A 1 179 ? 144.943 162.315 178.792 1.00 81.54  ?  168 LEU A CD2 1 
ATOM   1110  N N   . LEU A 1 180 ? 150.535 162.243 178.467 1.00 79.63  ?  169 LEU A N   1 
ATOM   1111  C CA  . LEU A 1 180 ? 151.698 162.271 177.586 1.00 79.63  ?  169 LEU A CA  1 
ATOM   1112  C C   . LEU A 1 180 ? 152.163 160.863 177.235 1.00 79.63  ?  169 LEU A C   1 
ATOM   1113  O O   . LEU A 1 180 ? 152.776 160.648 176.185 1.00 79.63  ?  169 LEU A O   1 
ATOM   1114  C CB  . LEU A 1 180 ? 152.828 163.070 178.231 1.00 79.63  ?  169 LEU A CB  1 
ATOM   1115  N N   . ASP A 1 181 ? 151.887 159.889 178.103 1.00 78.53  ?  170 ASP A N   1 
ATOM   1116  C CA  . ASP A 1 181 ? 152.263 158.512 177.798 1.00 78.53  ?  170 ASP A CA  1 
ATOM   1117  C C   . ASP A 1 181 ? 151.450 157.969 176.629 1.00 78.53  ?  170 ASP A C   1 
ATOM   1118  O O   . ASP A 1 181 ? 151.966 157.214 175.797 1.00 78.53  ?  170 ASP A O   1 
ATOM   1119  C CB  . ASP A 1 181 ? 152.092 157.633 179.036 1.00 78.53  ?  170 ASP A CB  1 
ATOM   1120  C CG  . ASP A 1 181 ? 153.130 157.922 180.098 1.00 78.53  ?  170 ASP A CG  1 
ATOM   1121  O OD1 . ASP A 1 181 ? 153.998 157.056 180.335 1.00 78.53  ?  170 ASP A OD1 1 
ATOM   1122  O OD2 . ASP A 1 181 ? 153.078 159.017 180.694 1.00 78.53  -1 170 ASP A OD2 1 
ATOM   1123  N N   . ASP A 1 182 ? 150.175 158.351 176.546 1.00 76.19  ?  171 ASP A N   1 
ATOM   1124  C CA  . ASP A 1 182 ? 149.349 157.923 175.421 1.00 76.19  ?  171 ASP A CA  1 
ATOM   1125  C C   . ASP A 1 182 ? 149.897 158.465 174.107 1.00 76.19  ?  171 ASP A C   1 
ATOM   1126  O O   . ASP A 1 182 ? 149.988 157.740 173.107 1.00 76.19  ?  171 ASP A O   1 
ATOM   1127  C CB  . ASP A 1 182 ? 147.905 158.377 175.632 1.00 76.19  ?  171 ASP A CB  1 
ATOM   1128  C CG  . ASP A 1 182 ? 147.038 157.296 176.240 1.00 76.19  ?  171 ASP A CG  1 
ATOM   1129  O OD1 . ASP A 1 182 ? 145.811 157.310 176.004 1.00 76.19  ?  171 ASP A OD1 1 
ATOM   1130  O OD2 . ASP A 1 182 ? 147.582 156.429 176.953 1.00 76.19  -1 171 ASP A OD2 1 
ATOM   1131  N N   . GLU A 1 183 ? 150.294 159.738 174.094 1.00 72.48  ?  172 GLU A N   1 
ATOM   1132  C CA  . GLU A 1 183 ? 150.816 160.324 172.867 1.00 72.48  ?  172 GLU A CA  1 
ATOM   1133  C C   . GLU A 1 183 ? 152.205 159.786 172.547 1.00 72.48  ?  172 GLU A C   1 
ATOM   1134  O O   . GLU A 1 183 ? 152.576 159.681 171.376 1.00 72.48  ?  172 GLU A O   1 
ATOM   1135  C CB  . GLU A 1 183 ? 150.821 161.850 172.966 1.00 72.48  ?  172 GLU A CB  1 
ATOM   1136  C CG  . GLU A 1 183 ? 151.984 162.432 173.729 1.00 72.48  ?  172 GLU A CG  1 
ATOM   1137  C CD  . GLU A 1 183 ? 151.875 163.929 173.896 1.00 72.48  ?  172 GLU A CD  1 
ATOM   1138  O OE1 . GLU A 1 183 ? 150.749 164.458 173.797 1.00 72.48  ?  172 GLU A OE1 1 
ATOM   1139  O OE2 . GLU A 1 183 ? 152.917 164.579 174.125 1.00 72.48  -1 172 GLU A OE2 1 
ATOM   1140  N N   . ARG A 1 184 ? 152.976 159.406 173.568 1.00 70.45  ?  173 ARG A N   1 
ATOM   1141  C CA  . ARG A 1 184 ? 154.265 158.770 173.314 1.00 70.45  ?  173 ARG A CA  1 
ATOM   1142  C C   . ARG A 1 184 ? 154.081 157.395 172.679 1.00 70.45  ?  173 ARG A C   1 
ATOM   1143  O O   . ARG A 1 184 ? 154.806 157.022 171.743 1.00 70.45  ?  173 ARG A O   1 
ATOM   1144  C CB  . ARG A 1 184 ? 155.055 158.660 174.617 1.00 70.45  ?  173 ARG A CB  1 
ATOM   1145  C CG  . ARG A 1 184 ? 156.139 157.605 174.597 1.00 70.45  ?  173 ARG A CG  1 
ATOM   1146  C CD  . ARG A 1 184 ? 156.599 157.251 176.000 1.00 70.45  ?  173 ARG A CD  1 
ATOM   1147  N NE  . ARG A 1 184 ? 155.625 156.429 176.714 1.00 70.45  ?  173 ARG A NE  1 
ATOM   1148  C CZ  . ARG A 1 184 ? 155.541 155.107 176.606 1.00 70.45  ?  173 ARG A CZ  1 
ATOM   1149  N NH1 . ARG A 1 184 ? 154.624 154.443 177.297 1.00 70.45  1  173 ARG A NH1 1 
ATOM   1150  N NH2 . ARG A 1 184 ? 156.370 154.448 175.808 1.00 70.45  ?  173 ARG A NH2 1 
ATOM   1151  N N   . VAL A 1 185 ? 153.110 156.629 173.174 1.00 65.47  ?  174 VAL A N   1 
ATOM   1152  C CA  . VAL A 1 185 ? 152.775 155.350 172.562 1.00 65.47  ?  174 VAL A CA  1 
ATOM   1153  C C   . VAL A 1 185 ? 152.323 155.547 171.121 1.00 65.47  ?  174 VAL A C   1 
ATOM   1154  O O   . VAL A 1 185 ? 152.708 154.784 170.226 1.00 65.47  ?  174 VAL A O   1 
ATOM   1155  C CB  . VAL A 1 185 ? 151.704 154.636 173.405 1.00 65.47  ?  174 VAL A CB  1 
ATOM   1156  C CG1 . VAL A 1 185 ? 151.146 153.444 172.660 1.00 65.47  ?  174 VAL A CG1 1 
ATOM   1157  C CG2 . VAL A 1 185 ? 152.285 154.208 174.735 1.00 65.47  ?  174 VAL A CG2 1 
ATOM   1158  N N   . ARG A 1 186 ? 151.502 156.569 170.873 1.00 58.56  ?  175 ARG A N   1 
ATOM   1159  C CA  . ARG A 1 186 ? 151.040 156.830 169.514 1.00 58.56  ?  175 ARG A CA  1 
ATOM   1160  C C   . ARG A 1 186 ? 152.193 157.222 168.598 1.00 58.56  ?  175 ARG A C   1 
ATOM   1161  O O   . ARG A 1 186 ? 152.233 156.811 167.435 1.00 58.56  ?  175 ARG A O   1 
ATOM   1162  C CB  . ARG A 1 186 ? 149.967 157.914 169.525 1.00 58.56  ?  175 ARG A CB  1 
ATOM   1163  C CG  . ARG A 1 186 ? 148.596 157.410 169.901 1.00 58.56  ?  175 ARG A CG  1 
ATOM   1164  C CD  . ARG A 1 186 ? 147.529 158.426 169.575 1.00 58.56  ?  175 ARG A CD  1 
ATOM   1165  N NE  . ARG A 1 186 ? 147.310 158.534 168.140 1.00 58.56  ?  175 ARG A NE  1 
ATOM   1166  C CZ  . ARG A 1 186 ? 146.564 157.694 167.434 1.00 58.56  ?  175 ARG A CZ  1 
ATOM   1167  N NH1 . ARG A 1 186 ? 145.960 156.681 168.032 1.00 58.56  1  175 ARG A NH1 1 
ATOM   1168  N NH2 . ARG A 1 186 ? 146.419 157.871 166.130 1.00 58.56  ?  175 ARG A NH2 1 
ATOM   1169  N N   . VAL A 1 187 ? 153.141 158.013 169.104 1.00 57.05  ?  176 VAL A N   1 
ATOM   1170  C CA  . VAL A 1 187 ? 154.298 158.401 168.305 1.00 57.05  ?  176 VAL A CA  1 
ATOM   1171  C C   . VAL A 1 187 ? 155.135 157.182 167.950 1.00 57.05  ?  176 VAL A C   1 
ATOM   1172  O O   . VAL A 1 187 ? 155.586 157.030 166.807 1.00 57.05  ?  176 VAL A O   1 
ATOM   1173  C CB  . VAL A 1 187 ? 155.130 159.459 169.051 1.00 57.05  ?  176 VAL A CB  1 
ATOM   1174  C CG1 . VAL A 1 187 ? 156.480 159.630 168.390 1.00 57.05  ?  176 VAL A CG1 1 
ATOM   1175  C CG2 . VAL A 1 187 ? 154.392 160.775 169.087 1.00 57.05  ?  176 VAL A CG2 1 
ATOM   1176  N N   . ALA A 1 188 ? 155.362 156.296 168.919 1.00 56.49  ?  177 ALA A N   1 
ATOM   1177  C CA  . ALA A 1 188 ? 156.138 155.091 168.640 1.00 56.49  ?  177 ALA A CA  1 
ATOM   1178  C C   . ALA A 1 188 ? 155.436 154.201 167.622 1.00 56.49  ?  177 ALA A C   1 
ATOM   1179  O O   . ALA A 1 188 ? 156.075 153.658 166.711 1.00 56.49  ?  177 ALA A O   1 
ATOM   1180  C CB  . ALA A 1 188 ? 156.399 154.326 169.935 1.00 56.49  ?  177 ALA A CB  1 
ATOM   1181  N N   . ALA A 1 189 ? 154.117 154.046 167.752 1.00 54.00  ?  178 ALA A N   1 
ATOM   1182  C CA  . ALA A 1 189 ? 153.381 153.218 166.803 1.00 54.00  ?  178 ALA A CA  1 
ATOM   1183  C C   . ALA A 1 189 ? 153.382 153.835 165.412 1.00 54.00  ?  178 ALA A C   1 
ATOM   1184  O O   . ALA A 1 189 ? 153.445 153.113 164.412 1.00 54.00  ?  178 ALA A O   1 
ATOM   1185  C CB  . ALA A 1 189 ? 151.954 152.993 167.298 1.00 54.00  ?  178 ALA A CB  1 
ATOM   1186  N N   . ALA A 1 190 ? 153.335 155.166 165.324 1.00 51.82  ?  179 ALA A N   1 
ATOM   1187  C CA  . ALA A 1 190 ? 153.399 155.822 164.023 1.00 51.82  ?  179 ALA A CA  1 
ATOM   1188  C C   . ALA A 1 190 ? 154.759 155.627 163.376 1.00 51.82  ?  179 ALA A C   1 
ATOM   1189  O O   . ALA A 1 190 ? 154.848 155.320 162.181 1.00 51.82  ?  179 ALA A O   1 
ATOM   1190  C CB  . ALA A 1 190 ? 153.087 157.309 164.167 1.00 51.82  ?  179 ALA A CB  1 
ATOM   1191  N N   . ALA A 1 191 ? 155.828 155.802 164.149 1.00 49.88  ?  180 ALA A N   1 
ATOM   1192  C CA  . ALA A 1 191 ? 157.166 155.576 163.623 1.00 49.88  ?  180 ALA A CA  1 
ATOM   1193  C C   . ALA A 1 191 ? 157.327 154.148 163.123 1.00 49.88  ?  180 ALA A C   1 
ATOM   1194  O O   . ALA A 1 191 ? 157.900 153.917 162.051 1.00 49.88  ?  180 ALA A O   1 
ATOM   1195  C CB  . ALA A 1 191 ? 158.202 155.895 164.696 1.00 49.88  ?  180 ALA A CB  1 
ATOM   1196  N N   . SER A 1 192 ? 156.806 153.173 163.869 1.00 51.68  ?  181 SER A N   1 
ATOM   1197  C CA  . SER A 1 192 ? 156.963 151.781 163.459 1.00 51.68  ?  181 SER A CA  1 
ATOM   1198  C C   . SER A 1 192 ? 156.130 151.459 162.221 1.00 51.68  ?  181 SER A C   1 
ATOM   1199  O O   . SER A 1 192 ? 156.599 150.752 161.317 1.00 51.68  ?  181 SER A O   1 
ATOM   1200  C CB  . SER A 1 192 ? 156.595 150.859 164.615 1.00 51.68  ?  181 SER A CB  1 
ATOM   1201  O OG  . SER A 1 192 ? 157.012 151.420 165.845 1.00 51.68  ?  181 SER A OG  1 
ATOM   1202  N N   . VAL A 1 193 ? 154.893 151.954 162.163 1.00 48.91  ?  182 VAL A N   1 
ATOM   1203  C CA  . VAL A 1 193 ? 154.069 151.760 160.974 1.00 48.91  ?  182 VAL A CA  1 
ATOM   1204  C C   . VAL A 1 193 ? 154.745 152.370 159.754 1.00 48.91  ?  182 VAL A C   1 
ATOM   1205  O O   . VAL A 1 193 ? 154.717 151.802 158.656 1.00 48.91  ?  182 VAL A O   1 
ATOM   1206  C CB  . VAL A 1 193 ? 152.662 152.345 161.211 1.00 48.91  ?  182 VAL A CB  1 
ATOM   1207  C CG1 . VAL A 1 193 ? 151.942 152.576 159.904 1.00 48.91  ?  182 VAL A CG1 1 
ATOM   1208  C CG2 . VAL A 1 193 ? 151.851 151.426 162.105 1.00 48.91  ?  182 VAL A CG2 1 
ATOM   1209  N N   . THR A 1 194 ? 155.389 153.522 159.937 1.00 48.44  ?  183 THR A N   1 
ATOM   1210  C CA  . THR A 1 194 ? 156.093 154.170 158.837 1.00 48.44  ?  183 THR A CA  1 
ATOM   1211  C C   . THR A 1 194 ? 157.295 153.356 158.381 1.00 48.44  ?  183 THR A C   1 
ATOM   1212  O O   . THR A 1 194 ? 157.536 153.214 157.177 1.00 48.44  ?  183 THR A O   1 
ATOM   1213  C CB  . THR A 1 194 ? 156.532 155.562 159.267 1.00 48.44  ?  183 THR A CB  1 
ATOM   1214  O OG1 . THR A 1 194 ? 155.378 156.306 159.660 1.00 48.44  ?  183 THR A OG1 1 
ATOM   1215  C CG2 . THR A 1 194 ? 157.234 156.270 158.141 1.00 48.44  ?  183 THR A CG2 1 
ATOM   1216  N N   . VAL A 1 195 ? 158.073 152.826 159.327 1.00 47.70  ?  184 VAL A N   1 
ATOM   1217  C CA  . VAL A 1 195 ? 159.236 152.027 158.952 1.00 47.70  ?  184 VAL A CA  1 
ATOM   1218  C C   . VAL A 1 195 ? 158.803 150.771 158.208 1.00 47.70  ?  184 VAL A C   1 
ATOM   1219  O O   . VAL A 1 195 ? 159.449 150.356 157.240 1.00 47.70  ?  184 VAL A O   1 
ATOM   1220  C CB  . VAL A 1 195 ? 160.091 151.687 160.186 1.00 47.70  ?  184 VAL A CB  1 
ATOM   1221  C CG1 . VAL A 1 195 ? 161.269 150.832 159.785 1.00 47.70  ?  184 VAL A CG1 1 
ATOM   1222  C CG2 . VAL A 1 195 ? 160.589 152.943 160.841 1.00 47.70  ?  184 VAL A CG2 1 
ATOM   1223  N N   . LEU A 1 196 ? 157.693 150.156 158.622 1.00 47.50  ?  185 LEU A N   1 
ATOM   1224  C CA  . LEU A 1 196 ? 157.253 148.952 157.921 1.00 47.50  ?  185 LEU A CA  1 
ATOM   1225  C C   . LEU A 1 196 ? 156.696 149.281 156.541 1.00 47.50  ?  185 LEU A C   1 
ATOM   1226  O O   . LEU A 1 196 ? 156.911 148.527 155.583 1.00 47.50  ?  185 LEU A O   1 
ATOM   1227  C CB  . LEU A 1 196 ? 156.222 148.187 158.747 1.00 47.50  ?  185 LEU A CB  1 
ATOM   1228  C CG  . LEU A 1 196 ? 155.845 146.825 158.154 1.00 47.50  ?  185 LEU A CG  1 
ATOM   1229  C CD1 . LEU A 1 196 ? 157.076 145.962 157.953 1.00 47.50  ?  185 LEU A CD1 1 
ATOM   1230  C CD2 . LEU A 1 196 ? 154.829 146.108 159.014 1.00 47.50  ?  185 LEU A CD2 1 
ATOM   1231  N N   . SER A 1 197 ? 155.982 150.402 156.411 1.00 46.59  ?  186 SER A N   1 
ATOM   1232  C CA  . SER A 1 197 ? 155.523 150.832 155.096 1.00 46.59  ?  186 SER A CA  1 
ATOM   1233  C C   . SER A 1 197 ? 156.699 151.085 154.162 1.00 46.59  ?  186 SER A C   1 
ATOM   1234  O O   . SER A 1 197 ? 156.674 150.684 152.992 1.00 46.59  ?  186 SER A O   1 
ATOM   1235  C CB  . SER A 1 197 ? 154.672 152.092 155.229 1.00 46.59  ?  186 SER A CB  1 
ATOM   1236  O OG  . SER A 1 197 ? 153.514 151.849 156.002 1.00 46.59  ?  186 SER A OG  1 
ATOM   1237  N N   . GLY A 1 198 ? 157.742 151.744 154.666 1.00 45.36  ?  187 GLY A N   1 
ATOM   1238  C CA  . GLY A 1 198 ? 158.913 151.992 153.846 1.00 45.36  ?  187 GLY A CA  1 
ATOM   1239  C C   . GLY A 1 198 ? 159.656 150.724 153.490 1.00 45.36  ?  187 GLY A C   1 
ATOM   1240  O O   . GLY A 1 198 ? 160.187 150.598 152.386 1.00 45.36  ?  187 GLY A O   1 
ATOM   1241  N N   . ILE A 1 199 ? 159.705 149.764 154.415 1.00 45.36  ?  188 ILE A N   1 
ATOM   1242  C CA  . ILE A 1 199 ? 160.327 148.478 154.117 1.00 45.36  ?  188 ILE A CA  1 
ATOM   1243  C C   . ILE A 1 199 ? 159.578 147.769 153.001 1.00 45.36  ?  188 ILE A C   1 
ATOM   1244  O O   . ILE A 1 199 ? 160.187 147.216 152.080 1.00 45.36  ?  188 ILE A O   1 
ATOM   1245  C CB  . ILE A 1 199 ? 160.402 147.614 155.391 1.00 45.36  ?  188 ILE A CB  1 
ATOM   1246  C CG1 . ILE A 1 199 ? 161.627 147.985 156.219 1.00 45.36  ?  188 ILE A CG1 1 
ATOM   1247  C CG2 . ILE A 1 199 ? 160.444 146.145 155.041 1.00 45.36  ?  188 ILE A CG2 1 
ATOM   1248  C CD1 . ILE A 1 199 ? 161.640 147.358 157.583 1.00 45.36  ?  188 ILE A CD1 1 
ATOM   1249  N N   . ILE A 1 200 ? 158.245 147.792 153.051 1.00 44.17  ?  189 ILE A N   1 
ATOM   1250  C CA  . ILE A 1 200 ? 157.448 147.141 152.014 1.00 44.17  ?  189 ILE A CA  1 
ATOM   1251  C C   . ILE A 1 200 ? 157.642 147.831 150.667 1.00 44.17  ?  189 ILE A C   1 
ATOM   1252  O O   . ILE A 1 200 ? 157.773 147.168 149.630 1.00 44.17  ?  189 ILE A O   1 
ATOM   1253  C CB  . ILE A 1 200 ? 155.968 147.105 152.432 1.00 44.17  ?  189 ILE A CB  1 
ATOM   1254  C CG1 . ILE A 1 200 ? 155.783 146.153 153.613 1.00 44.17  ?  189 ILE A CG1 1 
ATOM   1255  C CG2 . ILE A 1 200 ? 155.091 146.698 151.270 1.00 44.17  ?  189 ILE A CG2 1 
ATOM   1256  C CD1 . ILE A 1 200 ? 154.553 146.420 154.423 1.00 44.17  ?  189 ILE A CD1 1 
ATOM   1257  N N   . GLN A 1 201 ? 157.688 149.165 150.659 1.00 43.93  ?  190 GLN A N   1 
ATOM   1258  C CA  . GLN A 1 201 ? 157.916 149.881 149.404 1.00 43.93  ?  190 GLN A CA  1 
ATOM   1259  C C   . GLN A 1 201 ? 159.298 149.589 148.835 1.00 43.93  ?  190 GLN A C   1 
ATOM   1260  O O   . GLN A 1 201 ? 159.446 149.360 147.630 1.00 43.93  ?  190 GLN A O   1 
ATOM   1261  C CB  . GLN A 1 201 ? 157.750 151.383 149.610 1.00 43.93  ?  190 GLN A CB  1 
ATOM   1262  C CG  . GLN A 1 201 ? 156.363 151.811 149.984 1.00 43.93  ?  190 GLN A CG  1 
ATOM   1263  C CD  . GLN A 1 201 ? 156.211 153.306 149.999 1.00 43.93  ?  190 GLN A CD  1 
ATOM   1264  O OE1 . GLN A 1 201 ? 156.314 153.940 151.043 1.00 43.93  ?  190 GLN A OE1 1 
ATOM   1265  N NE2 . GLN A 1 201 ? 155.970 153.882 148.834 1.00 43.93  ?  190 GLN A NE2 1 
ATOM   1266  N N   . LEU A 1 202 ? 160.324 149.606 149.683 1.00 43.88  ?  191 LEU A N   1 
ATOM   1267  C CA  . LEU A 1 202 ? 161.679 149.345 149.214 1.00 43.88  ?  191 LEU A CA  1 
ATOM   1268  C C   . LEU A 1 202 ? 161.817 147.920 148.698 1.00 43.88  ?  191 LEU A C   1 
ATOM   1269  O O   . LEU A 1 202 ? 162.516 147.677 147.710 1.00 43.88  ?  191 LEU A O   1 
ATOM   1270  C CB  . LEU A 1 202 ? 162.671 149.622 150.340 1.00 43.88  ?  191 LEU A CB  1 
ATOM   1271  C CG  . LEU A 1 202 ? 164.133 149.253 150.130 1.00 43.88  ?  191 LEU A CG  1 
ATOM   1272  C CD1 . LEU A 1 202 ? 164.763 150.160 149.104 1.00 43.88  ?  191 LEU A CD1 1 
ATOM   1273  C CD2 . LEU A 1 202 ? 164.876 149.335 151.444 1.00 43.88  ?  191 LEU A CD2 1 
ATOM   1274  N N   . ALA A 1 203 ? 161.140 146.967 149.340 1.00 43.33  ?  192 ALA A N   1 
ATOM   1275  C CA  . ALA A 1 203 ? 161.166 145.590 148.861 1.00 43.33  ?  192 ALA A CA  1 
ATOM   1276  C C   . ALA A 1 203 ? 160.460 145.463 147.518 1.00 43.33  ?  192 ALA A C   1 
ATOM   1277  O O   . ALA A 1 203 ? 160.929 144.752 146.625 1.00 43.33  ?  192 ALA A O   1 
ATOM   1278  C CB  . ALA A 1 203 ? 160.530 144.667 149.895 1.00 43.33  ?  192 ALA A CB  1 
ATOM   1279  N N   . PHE A 1 204 ? 159.327 146.151 147.354 1.00 45.59  ?  193 PHE A N   1 
ATOM   1280  C CA  . PHE A 1 204 ? 158.623 146.113 146.075 1.00 45.59  ?  193 PHE A CA  1 
ATOM   1281  C C   . PHE A 1 204 ? 159.423 146.784 144.971 1.00 45.59  ?  193 PHE A C   1 
ATOM   1282  O O   . PHE A 1 204 ? 159.269 146.437 143.796 1.00 45.59  ?  193 PHE A O   1 
ATOM   1283  C CB  . PHE A 1 204 ? 157.258 146.782 146.207 1.00 45.59  ?  193 PHE A CB  1 
ATOM   1284  C CG  . PHE A 1 204 ? 156.142 145.827 146.474 1.00 45.59  ?  193 PHE A CG  1 
ATOM   1285  C CD1 . PHE A 1 204 ? 156.061 145.163 147.681 1.00 45.59  ?  193 PHE A CD1 1 
ATOM   1286  C CD2 . PHE A 1 204 ? 155.175 145.590 145.517 1.00 45.59  ?  193 PHE A CD2 1 
ATOM   1287  C CE1 . PHE A 1 204 ? 155.036 144.282 147.928 1.00 45.59  ?  193 PHE A CE1 1 
ATOM   1288  C CE2 . PHE A 1 204 ? 154.149 144.710 145.760 1.00 45.59  ?  193 PHE A CE2 1 
ATOM   1289  C CZ  . PHE A 1 204 ? 154.079 144.056 146.967 1.00 45.59  ?  193 PHE A CZ  1 
ATOM   1290  N N   . GLY A 1 205 ? 160.263 147.759 145.320 1.00 45.82  ?  194 GLY A N   1 
ATOM   1291  C CA  . GLY A 1 205 ? 161.106 148.388 144.321 1.00 45.82  ?  194 GLY A CA  1 
ATOM   1292  C C   . GLY A 1 205 ? 162.352 147.597 143.994 1.00 45.82  ?  194 GLY A C   1 
ATOM   1293  O O   . GLY A 1 205 ? 162.878 147.700 142.884 1.00 45.82  ?  194 GLY A O   1 
ATOM   1294  N N   . ILE A 1 206 ? 162.844 146.802 144.945 1.00 47.38  ?  195 ILE A N   1 
ATOM   1295  C CA  . ILE A 1 206 ? 164.009 145.964 144.686 1.00 47.38  ?  195 ILE A CA  1 
ATOM   1296  C C   . ILE A 1 206 ? 163.639 144.796 143.780 1.00 47.38  ?  195 ILE A C   1 
ATOM   1297  O O   . ILE A 1 206 ? 164.391 144.441 142.865 1.00 47.38  ?  195 ILE A O   1 
ATOM   1298  C CB  . ILE A 1 206 ? 164.622 145.488 146.016 1.00 47.38  ?  195 ILE A CB  1 
ATOM   1299  C CG1 . ILE A 1 206 ? 165.375 146.631 146.690 1.00 47.38  ?  195 ILE A CG1 1 
ATOM   1300  C CG2 . ILE A 1 206 ? 165.547 144.310 145.794 1.00 47.38  ?  195 ILE A CG2 1 
ATOM   1301  C CD1 . ILE A 1 206 ? 166.038 146.240 147.981 1.00 47.38  ?  195 ILE A CD1 1 
ATOM   1302  N N   . LEU A 1 207 ? 162.479 144.186 144.009 1.00 47.76  ?  196 LEU A N   1 
ATOM   1303  C CA  . LEU A 1 207 ? 161.999 143.100 143.165 1.00 47.76  ?  196 LEU A CA  1 
ATOM   1304  C C   . LEU A 1 207 ? 161.481 143.578 141.816 1.00 47.76  ?  196 LEU A C   1 
ATOM   1305  O O   . LEU A 1 207 ? 161.046 142.750 141.014 1.00 47.76  ?  196 LEU A O   1 
ATOM   1306  C CB  . LEU A 1 207 ? 160.896 142.321 143.881 1.00 47.76  ?  196 LEU A CB  1 
ATOM   1307  C CG  . LEU A 1 207 ? 161.203 141.838 145.296 1.00 47.76  ?  196 LEU A CG  1 
ATOM   1308  C CD1 . LEU A 1 207 ? 159.966 141.230 145.923 1.00 47.76  ?  196 LEU A CD1 1 
ATOM   1309  C CD2 . LEU A 1 207 ? 162.344 140.846 145.285 1.00 47.76  ?  196 LEU A CD2 1 
ATOM   1310  N N   . ARG A 1 208 ? 161.509 144.886 141.561 1.00 47.46  ?  197 ARG A N   1 
ATOM   1311  C CA  . ARG A 1 208 ? 161.111 145.472 140.281 1.00 47.46  ?  197 ARG A CA  1 
ATOM   1312  C C   . ARG A 1 208 ? 159.637 145.201 139.977 1.00 47.46  ?  197 ARG A C   1 
ATOM   1313  O O   . ARG A 1 208 ? 159.278 144.728 138.900 1.00 47.46  ?  197 ARG A O   1 
ATOM   1314  C CB  . ARG A 1 208 ? 162.002 144.981 139.133 1.00 47.46  ?  197 ARG A CB  1 
ATOM   1315  C CG  . ARG A 1 208 ? 163.497 144.890 139.429 1.00 47.46  ?  197 ARG A CG  1 
ATOM   1316  C CD  . ARG A 1 208 ? 164.036 146.105 140.160 1.00 47.46  ?  197 ARG A CD  1 
ATOM   1317  N NE  . ARG A 1 208 ? 164.513 147.149 139.264 1.00 47.46  ?  197 ARG A NE  1 
ATOM   1318  C CZ  . ARG A 1 208 ? 164.869 148.361 139.671 1.00 47.46  ?  197 ARG A CZ  1 
ATOM   1319  N NH1 . ARG A 1 208 ? 164.799 148.673 140.955 1.00 47.46  1  197 ARG A NH1 1 
ATOM   1320  N NH2 . ARG A 1 208 ? 165.293 149.261 138.797 1.00 47.46  ?  197 ARG A NH2 1 
ATOM   1321  N N   . ILE A 1 209 ? 158.774 145.521 140.942 1.00 46.87  ?  198 ILE A N   1 
ATOM   1322  C CA  . ILE A 1 209 ? 157.334 145.349 140.771 1.00 46.87  ?  198 ILE A CA  1 
ATOM   1323  C C   . ILE A 1 209 ? 156.664 146.714 140.710 1.00 46.87  ?  198 ILE A C   1 
ATOM   1324  O O   . ILE A 1 209 ? 155.518 146.875 141.140 1.00 46.87  ?  198 ILE A O   1 
ATOM   1325  C CB  . ILE A 1 209 ? 156.721 144.496 141.898 1.00 46.87  ?  198 ILE A CB  1 
ATOM   1326  C CG1 . ILE A 1 209 ? 157.722 143.475 142.419 1.00 46.87  ?  198 ILE A CG1 1 
ATOM   1327  C CG2 . ILE A 1 209 ? 155.493 143.768 141.404 1.00 46.87  ?  198 ILE A CG2 1 
ATOM   1328  C CD1 . ILE A 1 209 ? 157.208 142.695 143.597 1.00 46.87  ?  198 ILE A CD1 1 
ATOM   1329  N N   . GLY A 1 210 ? 157.368 147.706 140.180 1.00 45.82  ?  199 GLY A N   1 
ATOM   1330  C CA  . GLY A 1 210 ? 156.833 149.050 140.110 1.00 45.82  ?  199 GLY A CA  1 
ATOM   1331  C C   . GLY A 1 210 ? 155.710 149.238 139.115 1.00 45.82  ?  199 GLY A C   1 
ATOM   1332  O O   . GLY A 1 210 ? 155.326 150.374 138.820 1.00 45.82  ?  199 GLY A O   1 
ATOM   1333  N N   . PHE A 1 211 ? 155.172 148.141 138.586 1.00 43.19  ?  200 PHE A N   1 
ATOM   1334  C CA  . PHE A 1 211 ? 154.067 148.187 137.643 1.00 43.19  ?  200 PHE A CA  1 
ATOM   1335  C C   . PHE A 1 211 ? 152.733 147.837 138.285 1.00 43.19  ?  200 PHE A C   1 
ATOM   1336  O O   . PHE A 1 211 ? 151.745 147.666 137.568 1.00 43.19  ?  200 PHE A O   1 
ATOM   1337  C CB  . PHE A 1 211 ? 154.334 147.254 136.456 1.00 43.19  ?  200 PHE A CB  1 
ATOM   1338  C CG  . PHE A 1 211 ? 154.540 145.814 136.840 1.00 43.19  ?  200 PHE A CG  1 
ATOM   1339  C CD1 . PHE A 1 211 ? 155.806 145.273 136.871 1.00 43.19  ?  200 PHE A CD1 1 
ATOM   1340  C CD2 . PHE A 1 211 ? 153.466 144.999 137.155 1.00 43.19  ?  200 PHE A CD2 1 
ATOM   1341  C CE1 . PHE A 1 211 ? 155.996 143.958 137.225 1.00 43.19  ?  200 PHE A CE1 1 
ATOM   1342  C CE2 . PHE A 1 211 ? 153.656 143.689 137.512 1.00 43.19  ?  200 PHE A CE2 1 
ATOM   1343  C CZ  . PHE A 1 211 ? 154.918 143.167 137.541 1.00 43.19  ?  200 PHE A CZ  1 
ATOM   1344  N N   . VAL A 1 212 ? 152.679 147.713 139.611 1.00 43.37  ?  201 VAL A N   1 
ATOM   1345  C CA  . VAL A 1 212 ? 151.417 147.399 140.272 1.00 43.37  ?  201 VAL A CA  1 
ATOM   1346  C C   . VAL A 1 212 ? 150.425 148.546 140.204 1.00 43.37  ?  201 VAL A C   1 
ATOM   1347  O O   . VAL A 1 212 ? 149.227 148.332 140.417 1.00 43.37  ?  201 VAL A O   1 
ATOM   1348  C CB  . VAL A 1 212 ? 151.645 147.000 141.743 1.00 43.37  ?  201 VAL A CB  1 
ATOM   1349  C CG1 . VAL A 1 212 ? 152.240 145.611 141.818 1.00 43.37  ?  201 VAL A CG1 1 
ATOM   1350  C CG2 . VAL A 1 212 ? 152.542 148.006 142.437 1.00 43.37  ?  201 VAL A CG2 1 
ATOM   1351  N N   . VAL A 1 213 ? 150.893 149.756 139.893 1.00 42.96  ?  202 VAL A N   1 
ATOM   1352  C CA  . VAL A 1 213 ? 150.002 150.899 139.774 1.00 42.96  ?  202 VAL A CA  1 
ATOM   1353  C C   . VAL A 1 213 ? 148.982 150.709 138.664 1.00 42.96  ?  202 VAL A C   1 
ATOM   1354  O O   . VAL A 1 213 ? 147.978 151.426 138.625 1.00 42.96  ?  202 VAL A O   1 
ATOM   1355  C CB  . VAL A 1 213 ? 150.817 152.180 139.540 1.00 42.96  ?  202 VAL A CB  1 
ATOM   1356  C CG1 . VAL A 1 213 ? 151.688 152.469 140.735 1.00 42.96  ?  202 VAL A CG1 1 
ATOM   1357  C CG2 . VAL A 1 213 ? 151.664 152.040 138.290 1.00 42.96  ?  202 VAL A CG2 1 
ATOM   1358  N N   . ILE A 1 214 ? 149.218 149.763 137.751 1.00 40.70  ?  203 ILE A N   1 
ATOM   1359  C CA  . ILE A 1 214 ? 148.269 149.502 136.679 1.00 40.70  ?  203 ILE A CA  1 
ATOM   1360  C C   . ILE A 1 214 ? 147.055 148.741 137.181 1.00 40.70  ?  203 ILE A C   1 
ATOM   1361  O O   . ILE A 1 214 ? 146.060 148.634 136.459 1.00 40.70  ?  203 ILE A O   1 
ATOM   1362  C CB  . ILE A 1 214 ? 148.949 148.734 135.531 1.00 40.70  ?  203 ILE A CB  1 
ATOM   1363  C CG1 . ILE A 1 214 ? 149.071 147.252 135.884 1.00 40.70  ?  203 ILE A CG1 1 
ATOM   1364  C CG2 . ILE A 1 214 ? 150.302 149.340 135.226 1.00 40.70  ?  203 ILE A CG2 1 
ATOM   1365  C CD1 . ILE A 1 214 ? 149.986 146.471 134.985 1.00 40.70  ?  203 ILE A CD1 1 
ATOM   1366  N N   . TYR A 1 215 ? 147.102 148.216 138.400 1.00 41.09  ?  204 TYR A N   1 
ATOM   1367  C CA  . TYR A 1 215 ? 145.971 147.480 138.943 1.00 41.09  ?  204 TYR A CA  1 
ATOM   1368  C C   . TYR A 1 215 ? 144.932 148.383 139.582 1.00 41.09  ?  204 TYR A C   1 
ATOM   1369  O O   . TYR A 1 215 ? 143.989 147.879 140.195 1.00 41.09  ?  204 TYR A O   1 
ATOM   1370  C CB  . TYR A 1 215 ? 146.453 146.445 139.957 1.00 41.09  ?  204 TYR A CB  1 
ATOM   1371  C CG  . TYR A 1 215 ? 147.370 145.415 139.357 1.00 41.09  ?  204 TYR A CG  1 
ATOM   1372  C CD1 . TYR A 1 215 ? 148.646 145.229 139.846 1.00 41.09  ?  204 TYR A CD1 1 
ATOM   1373  C CD2 . TYR A 1 215 ? 146.962 144.640 138.289 1.00 41.09  ?  204 TYR A CD2 1 
ATOM   1374  C CE1 . TYR A 1 215 ? 149.488 144.298 139.296 1.00 41.09  ?  204 TYR A CE1 1 
ATOM   1375  C CE2 . TYR A 1 215 ? 147.798 143.706 137.733 1.00 41.09  ?  204 TYR A CE2 1 
ATOM   1376  C CZ  . TYR A 1 215 ? 149.057 143.537 138.243 1.00 41.09  ?  204 TYR A CZ  1 
ATOM   1377  O OH  . TYR A 1 215 ? 149.891 142.603 137.686 1.00 41.09  ?  204 TYR A OH  1 
ATOM   1378  N N   . LEU A 1 216 ? 145.085 149.696 139.451 1.00 41.01  ?  205 LEU A N   1 
ATOM   1379  C CA  . LEU A 1 216 ? 144.121 150.672 139.942 1.00 41.01  ?  205 LEU A CA  1 
ATOM   1380  C C   . LEU A 1 216 ? 143.688 151.525 138.761 1.00 41.01  ?  205 LEU A C   1 
ATOM   1381  O O   . LEU A 1 216 ? 144.492 152.283 138.213 1.00 41.01  ?  205 LEU A O   1 
ATOM   1382  C CB  . LEU A 1 216 ? 144.724 151.530 141.052 1.00 41.01  ?  205 LEU A CB  1 
ATOM   1383  C CG  . LEU A 1 216 ? 145.567 150.786 142.083 1.00 41.01  ?  205 LEU A CG  1 
ATOM   1384  C CD1 . LEU A 1 216 ? 146.358 151.755 142.919 1.00 41.01  ?  205 LEU A CD1 1 
ATOM   1385  C CD2 . LEU A 1 216 ? 144.688 149.948 142.962 1.00 41.01  ?  205 LEU A CD2 1 
ATOM   1386  N N   . SER A 1 217 ? 142.426 151.400 138.363 1.00 41.35  ?  206 SER A N   1 
ATOM   1387  C CA  . SER A 1 217 ? 141.936 152.138 137.215 1.00 41.35  ?  206 SER A CA  1 
ATOM   1388  C C   . SER A 1 217 ? 141.724 153.602 137.579 1.00 41.35  ?  206 SER A C   1 
ATOM   1389  O O   . SER A 1 217 ? 141.970 154.037 138.705 1.00 41.35  ?  206 SER A O   1 
ATOM   1390  C CB  . SER A 1 217 ? 140.645 151.518 136.691 1.00 41.35  ?  206 SER A CB  1 
ATOM   1391  O OG  . SER A 1 217 ? 139.885 150.971 137.744 1.00 41.35  ?  206 SER A OG  1 
ATOM   1392  N N   . GLU A 1 218 ? 141.264 154.375 136.598 1.00 45.48  ?  207 GLU A N   1 
ATOM   1393  C CA  . GLU A 1 218 ? 140.949 155.772 136.855 1.00 45.48  ?  207 GLU A CA  1 
ATOM   1394  C C   . GLU A 1 218 ? 139.709 155.913 137.721 1.00 45.48  ?  207 GLU A C   1 
ATOM   1395  O O   . GLU A 1 218 ? 139.653 156.802 138.574 1.00 45.48  ?  207 GLU A O   1 
ATOM   1396  C CB  . GLU A 1 218 ? 140.750 156.522 135.542 1.00 45.48  ?  207 GLU A CB  1 
ATOM   1397  C CG  . GLU A 1 218 ? 141.975 156.581 134.655 1.00 45.48  ?  207 GLU A CG  1 
ATOM   1398  C CD  . GLU A 1 218 ? 141.701 157.308 133.360 1.00 45.48  ?  207 GLU A CD  1 
ATOM   1399  O OE1 . GLU A 1 218 ? 142.666 157.611 132.629 1.00 45.48  ?  207 GLU A OE1 1 
ATOM   1400  O OE2 . GLU A 1 218 ? 140.516 157.575 133.074 1.00 45.48  -1 207 GLU A OE2 1 
ATOM   1401  N N   . SER A 1 219 ? 138.711 155.049 137.526 1.00 43.12  ?  208 SER A N   1 
ATOM   1402  C CA  . SER A 1 219 ? 137.461 155.182 138.265 1.00 43.12  ?  208 SER A CA  1 
ATOM   1403  C C   . SER A 1 219 ? 137.583 154.613 139.673 1.00 43.12  ?  208 SER A C   1 
ATOM   1404  O O   . SER A 1 219 ? 136.990 155.149 140.615 1.00 43.12  ?  208 SER A O   1 
ATOM   1405  C CB  . SER A 1 219 ? 136.328 154.512 137.496 1.00 43.12  ?  208 SER A CB  1 
ATOM   1406  O OG  . SER A 1 219 ? 136.806 153.413 136.751 1.00 43.12  ?  208 SER A OG  1 
ATOM   1407  N N   . LEU A 1 220 ? 138.358 153.541 139.842 1.00 41.24  ?  209 LEU A N   1 
ATOM   1408  C CA  . LEU A 1 220 ? 138.687 153.087 141.188 1.00 41.24  ?  209 LEU A CA  1 
ATOM   1409  C C   . LEU A 1 220 ? 139.385 154.185 141.974 1.00 41.24  ?  209 LEU A C   1 
ATOM   1410  O O   . LEU A 1 220 ? 139.017 154.471 143.118 1.00 41.24  ?  209 LEU A O   1 
ATOM   1411  C CB  . LEU A 1 220 ? 139.566 151.838 141.129 1.00 41.24  ?  209 LEU A CB  1 
ATOM   1412  C CG  . LEU A 1 220 ? 139.936 151.167 142.455 1.00 41.24  ?  209 LEU A CG  1 
ATOM   1413  C CD1 . LEU A 1 220 ? 139.942 149.680 142.290 1.00 41.24  ?  209 LEU A CD1 1 
ATOM   1414  C CD2 . LEU A 1 220 ? 141.282 151.620 142.961 1.00 41.24  ?  209 LEU A CD2 1 
ATOM   1415  N N   . ILE A 1 221 ? 140.387 154.822 141.368 1.00 42.01  ?  210 ILE A N   1 
ATOM   1416  C CA  . ILE A 1 221 ? 141.123 155.878 142.051 1.00 42.01  ?  210 ILE A CA  1 
ATOM   1417  C C   . ILE A 1 221 ? 140.223 157.079 142.310 1.00 42.01  ?  210 ILE A C   1 
ATOM   1418  O O   . ILE A 1 221 ? 140.300 157.711 143.367 1.00 42.01  ?  210 ILE A O   1 
ATOM   1419  C CB  . ILE A 1 221 ? 142.370 156.258 141.234 1.00 42.01  ?  210 ILE A CB  1 
ATOM   1420  C CG1 . ILE A 1 221 ? 143.449 155.188 141.395 1.00 42.01  ?  210 ILE A CG1 1 
ATOM   1421  C CG2 . ILE A 1 221 ? 142.903 157.611 141.655 1.00 42.01  ?  210 ILE A CG2 1 
ATOM   1422  C CD1 . ILE A 1 221 ? 144.627 155.375 140.485 1.00 42.01  ?  210 ILE A CD1 1 
ATOM   1423  N N   . SER A 1 222 ? 139.334 157.396 141.368 1.00 42.50  ?  211 SER A N   1 
ATOM   1424  C CA  . SER A 1 222 ? 138.432 158.528 141.541 1.00 42.50  ?  211 SER A CA  1 
ATOM   1425  C C   . SER A 1 222 ? 137.480 158.304 142.708 1.00 42.50  ?  211 SER A C   1 
ATOM   1426  O O   . SER A 1 222 ? 137.325 159.172 143.574 1.00 42.50  ?  211 SER A O   1 
ATOM   1427  C CB  . SER A 1 222 ? 137.656 158.772 140.248 1.00 42.50  ?  211 SER A CB  1 
ATOM   1428  O OG  . SER A 1 222 ? 137.141 160.088 140.191 1.00 42.50  ?  211 SER A OG  1 
ATOM   1429  N N   . GLY A 1 223 ? 136.829 157.140 142.748 1.00 41.15  ?  212 GLY A N   1 
ATOM   1430  C CA  . GLY A 1 223 ? 135.919 156.856 143.843 1.00 41.15  ?  212 GLY A CA  1 
ATOM   1431  C C   . GLY A 1 223 ? 136.631 156.756 145.175 1.00 41.15  ?  212 GLY A C   1 
ATOM   1432  O O   . GLY A 1 223 ? 136.127 157.232 146.196 1.00 41.15  ?  212 GLY A O   1 
ATOM   1433  N N   . PHE A 1 224 ? 137.820 156.149 145.183 1.00 41.12  ?  213 PHE A N   1 
ATOM   1434  C CA  . PHE A 1 224 ? 138.586 156.041 146.416 1.00 41.12  ?  213 PHE A CA  1 
ATOM   1435  C C   . PHE A 1 224 ? 138.977 157.410 146.941 1.00 41.12  ?  213 PHE A C   1 
ATOM   1436  O O   . PHE A 1 224 ? 138.832 157.683 148.133 1.00 41.12  ?  213 PHE A O   1 
ATOM   1437  C CB  . PHE A 1 224 ? 139.828 155.182 146.192 1.00 41.12  ?  213 PHE A CB  1 
ATOM   1438  C CG  . PHE A 1 224 ? 140.731 155.097 147.390 1.00 41.12  ?  213 PHE A CG  1 
ATOM   1439  C CD1 . PHE A 1 224 ? 140.498 154.166 148.382 1.00 41.12  ?  213 PHE A CD1 1 
ATOM   1440  C CD2 . PHE A 1 224 ? 141.814 155.946 147.521 1.00 41.12  ?  213 PHE A CD2 1 
ATOM   1441  C CE1 . PHE A 1 224 ? 141.319 154.089 149.477 1.00 41.12  ?  213 PHE A CE1 1 
ATOM   1442  C CE2 . PHE A 1 224 ? 142.633 155.870 148.616 1.00 41.12  ?  213 PHE A CE2 1 
ATOM   1443  C CZ  . PHE A 1 224 ? 142.385 154.940 149.594 1.00 41.12  ?  213 PHE A CZ  1 
ATOM   1444  N N   . THR A 1 225 ? 139.470 158.289 146.069 1.00 43.79  ?  214 THR A N   1 
ATOM   1445  C CA  . THR A 1 225 ? 139.898 159.606 146.518 1.00 43.79  ?  214 THR A CA  1 
ATOM   1446  C C   . THR A 1 225 ? 138.721 160.493 146.895 1.00 43.79  ?  214 THR A C   1 
ATOM   1447  O O   . THR A 1 225 ? 138.858 161.330 147.787 1.00 43.79  ?  214 THR A O   1 
ATOM   1448  C CB  . THR A 1 225 ? 140.753 160.277 145.445 1.00 43.79  ?  214 THR A CB  1 
ATOM   1449  O OG1 . THR A 1 225 ? 140.058 160.265 144.196 1.00 43.79  ?  214 THR A OG1 1 
ATOM   1450  C CG2 . THR A 1 225 ? 142.069 159.543 145.289 1.00 43.79  ?  214 THR A CG2 1 
ATOM   1451  N N   . THR A 1 226 ? 137.553 160.311 146.278 1.00 43.17  ?  215 THR A N   1 
ATOM   1452  C CA  . THR A 1 226 ? 136.381 161.065 146.712 1.00 43.17  ?  215 THR A CA  1 
ATOM   1453  C C   . THR A 1 226 ? 135.914 160.611 148.091 1.00 43.17  ?  215 THR A C   1 
ATOM   1454  O O   . THR A 1 226 ? 135.645 161.438 148.974 1.00 43.17  ?  215 THR A O   1 
ATOM   1455  C CB  . THR A 1 226 ? 135.255 160.924 145.689 1.00 43.17  ?  215 THR A CB  1 
ATOM   1456  O OG1 . THR A 1 226 ? 135.688 161.448 144.431 1.00 43.17  ?  215 THR A OG1 1 
ATOM   1457  C CG2 . THR A 1 226 ? 134.048 161.701 146.139 1.00 43.17  ?  215 THR A CG2 1 
ATOM   1458  N N   . ALA A 1 227 ? 135.819 159.296 148.301 1.00 42.33  ?  216 ALA A N   1 
ATOM   1459  C CA  . ALA A 1 227 ? 135.460 158.789 149.620 1.00 42.33  ?  216 ALA A CA  1 
ATOM   1460  C C   . ALA A 1 227 ? 136.490 159.185 150.668 1.00 42.33  ?  216 ALA A C   1 
ATOM   1461  O O   . ALA A 1 227 ? 136.142 159.477 151.815 1.00 42.33  ?  216 ALA A O   1 
ATOM   1462  C CB  . ALA A 1 227 ? 135.300 157.274 149.567 1.00 42.33  ?  216 ALA A CB  1 
ATOM   1463  N N   . ALA A 1 228 ? 137.766 159.221 150.287 1.00 43.96  ?  217 ALA A N   1 
ATOM   1464  C CA  . ALA A 1 228 ? 138.814 159.600 151.222 1.00 43.96  ?  217 ALA A CA  1 
ATOM   1465  C C   . ALA A 1 228 ? 138.791 161.090 151.518 1.00 43.96  ?  217 ALA A C   1 
ATOM   1466  O O   . ALA A 1 228 ? 139.134 161.501 152.626 1.00 43.96  ?  217 ALA A O   1 
ATOM   1467  C CB  . ALA A 1 228 ? 140.170 159.182 150.668 1.00 43.96  ?  217 ALA A CB  1 
ATOM   1468  N N   . ALA A 1 229 ? 138.395 161.913 150.547 1.00 45.51  ?  218 ALA A N   1 
ATOM   1469  C CA  . ALA A 1 229 ? 138.193 163.327 150.825 1.00 45.51  ?  218 ALA A CA  1 
ATOM   1470  C C   . ALA A 1 229 ? 137.041 163.528 151.794 1.00 45.51  ?  218 ALA A C   1 
ATOM   1471  O O   . ALA A 1 229 ? 137.097 164.407 152.659 1.00 45.51  ?  218 ALA A O   1 
ATOM   1472  C CB  . ALA A 1 229 ? 137.942 164.090 149.528 1.00 45.51  ?  218 ALA A CB  1 
ATOM   1473  N N   . VAL A 1 230 ? 135.988 162.719 151.671 1.00 45.58  ?  219 VAL A N   1 
ATOM   1474  C CA  . VAL A 1 230 ? 134.909 162.761 152.659 1.00 45.58  ?  219 VAL A CA  1 
ATOM   1475  C C   . VAL A 1 230 ? 135.427 162.350 154.033 1.00 45.58  ?  219 VAL A C   1 
ATOM   1476  O O   . VAL A 1 230 ? 135.071 162.950 155.055 1.00 45.58  ?  219 VAL A O   1 
ATOM   1477  C CB  . VAL A 1 230 ? 133.736 161.875 152.202 1.00 45.58  ?  219 VAL A CB  1 
ATOM   1478  C CG1 . VAL A 1 230 ? 132.667 161.814 153.268 1.00 45.58  ?  219 VAL A CG1 1 
ATOM   1479  C CG2 . VAL A 1 230 ? 133.158 162.400 150.905 1.00 45.58  ?  219 VAL A CG2 1 
ATOM   1480  N N   . HIS A 1 231 ? 136.273 161.318 154.077 1.00 45.32  ?  220 HIS A N   1 
ATOM   1481  C CA  . HIS A 1 231 ? 136.901 160.898 155.327 1.00 45.32  ?  220 HIS A CA  1 
ATOM   1482  C C   . HIS A 1 231 ? 137.692 162.034 155.960 1.00 45.32  ?  220 HIS A C   1 
ATOM   1483  O O   . HIS A 1 231 ? 137.605 162.272 157.170 1.00 45.32  ?  220 HIS A O   1 
ATOM   1484  C CB  . HIS A 1 231 ? 137.824 159.707 155.072 1.00 45.32  ?  220 HIS A CB  1 
ATOM   1485  C CG  . HIS A 1 231 ? 137.145 158.376 155.133 1.00 45.32  ?  220 HIS A CG  1 
ATOM   1486  N ND1 . HIS A 1 231 ? 137.286 157.521 156.201 1.00 45.32  ?  220 HIS A ND1 1 
ATOM   1487  C CD2 . HIS A 1 231 ? 136.340 157.746 154.247 1.00 45.32  ?  220 HIS A CD2 1 
ATOM   1488  C CE1 . HIS A 1 231 ? 136.586 156.423 155.976 1.00 45.32  ?  220 HIS A CE1 1 
ATOM   1489  N NE2 . HIS A 1 231 ? 136.004 156.535 154.798 1.00 45.32  ?  220 HIS A NE2 1 
ATOM   1490  N N   . VAL A 1 232 ? 138.486 162.739 155.155 1.00 48.29  ?  221 VAL A N   1 
ATOM   1491  C CA  . VAL A 1 232 ? 139.329 163.809 155.679 1.00 48.29  ?  221 VAL A CA  1 
ATOM   1492  C C   . VAL A 1 232 ? 138.480 164.999 156.104 1.00 48.29  ?  221 VAL A C   1 
ATOM   1493  O O   . VAL A 1 232 ? 138.809 165.696 157.067 1.00 48.29  ?  221 VAL A O   1 
ATOM   1494  C CB  . VAL A 1 232 ? 140.398 164.205 154.644 1.00 48.29  ?  221 VAL A CB  1 
ATOM   1495  C CG1 . VAL A 1 232 ? 141.238 165.351 155.154 1.00 48.29  ?  221 VAL A CG1 1 
ATOM   1496  C CG2 . VAL A 1 232 ? 141.284 163.026 154.319 1.00 48.29  ?  221 VAL A CG2 1 
ATOM   1497  N N   . LEU A 1 233 ? 137.375 165.247 155.402 1.00 49.36  ?  222 LEU A N   1 
ATOM   1498  C CA  . LEU A 1 233 ? 136.439 166.281 155.830 1.00 49.36  ?  222 LEU A CA  1 
ATOM   1499  C C   . LEU A 1 233 ? 135.876 165.961 157.204 1.00 49.36  ?  222 LEU A C   1 
ATOM   1500  O O   . LEU A 1 233 ? 135.856 166.815 158.094 1.00 49.36  ?  222 LEU A O   1 
ATOM   1501  C CB  . LEU A 1 233 ? 135.308 166.416 154.807 1.00 49.36  ?  222 LEU A CB  1 
ATOM   1502  C CG  . LEU A 1 233 ? 134.483 167.700 154.658 1.00 49.36  ?  222 LEU A CG  1 
ATOM   1503  C CD1 . LEU A 1 233 ? 133.463 167.497 153.564 1.00 49.36  ?  222 LEU A CD1 1 
ATOM   1504  C CD2 . LEU A 1 233 ? 133.782 168.109 155.936 1.00 49.36  ?  222 LEU A CD2 1 
ATOM   1505  N N   . VAL A 1 234 ? 135.402 164.729 157.390 1.00 50.18  ?  223 VAL A N   1 
ATOM   1506  C CA  . VAL A 1 234 ? 134.804 164.358 158.667 1.00 50.18  ?  223 VAL A CA  1 
ATOM   1507  C C   . VAL A 1 234 ? 135.851 164.355 159.772 1.00 50.18  ?  223 VAL A C   1 
ATOM   1508  O O   . VAL A 1 234 ? 135.544 164.677 160.925 1.00 50.18  ?  223 VAL A O   1 
ATOM   1509  C CB  . VAL A 1 234 ? 134.092 162.997 158.540 1.00 50.18  ?  223 VAL A CB  1 
ATOM   1510  C CG1 . VAL A 1 234 ? 133.625 162.504 159.891 1.00 50.18  ?  223 VAL A CG1 1 
ATOM   1511  C CG2 . VAL A 1 234 ? 132.920 163.106 157.588 1.00 50.18  ?  223 VAL A CG2 1 
ATOM   1512  N N   . SER A 1 235 ? 137.101 164.030 159.444 1.00 51.92  ?  224 SER A N   1 
ATOM   1513  C CA  . SER A 1 235 ? 138.148 163.966 160.456 1.00 51.92  ?  224 SER A CA  1 
ATOM   1514  C C   . SER A 1 235 ? 138.608 165.336 160.931 1.00 51.92  ?  224 SER A C   1 
ATOM   1515  O O   . SER A 1 235 ? 139.203 165.429 162.007 1.00 51.92  ?  224 SER A O   1 
ATOM   1516  C CB  . SER A 1 235 ? 139.347 163.188 159.923 1.00 51.92  ?  224 SER A CB  1 
ATOM   1517  O OG  . SER A 1 235 ? 139.078 161.800 159.923 1.00 51.92  ?  224 SER A OG  1 
ATOM   1518  N N   . GLN A 1 236 ? 138.362 166.390 160.162 1.00 53.57  ?  225 GLN A N   1 
ATOM   1519  C CA  . GLN A 1 236 ? 138.723 167.734 160.589 1.00 53.57  ?  225 GLN A CA  1 
ATOM   1520  C C   . GLN A 1 236 ? 137.636 168.404 161.413 1.00 53.57  ?  225 GLN A C   1 
ATOM   1521  O O   . GLN A 1 236 ? 137.814 169.556 161.808 1.00 53.57  ?  225 GLN A O   1 
ATOM   1522  C CB  . GLN A 1 236 ? 139.044 168.618 159.382 1.00 53.57  ?  225 GLN A CB  1 
ATOM   1523  C CG  . GLN A 1 236 ? 140.118 168.083 158.460 1.00 53.57  ?  225 GLN A CG  1 
ATOM   1524  C CD  . GLN A 1 236 ? 141.510 168.224 159.023 1.00 53.57  ?  225 GLN A CD  1 
ATOM   1525  O OE1 . GLN A 1 236 ? 141.711 168.821 160.075 1.00 53.57  ?  225 GLN A OE1 1 
ATOM   1526  N NE2 . GLN A 1 236 ? 142.483 167.675 158.318 1.00 53.57  ?  225 GLN A NE2 1 
ATOM   1527  N N   . LEU A 1 237 ? 136.525 167.718 161.686 1.00 52.46  ?  226 LEU A N   1 
ATOM   1528  C CA  . LEU A 1 237 ? 135.421 168.355 162.393 1.00 52.46  ?  226 LEU A CA  1 
ATOM   1529  C C   . LEU A 1 237 ? 135.704 168.496 163.881 1.00 52.46  ?  226 LEU A C   1 
ATOM   1530  O O   . LEU A 1 237 ? 135.199 169.425 164.517 1.00 52.46  ?  226 LEU A O   1 
ATOM   1531  C CB  . LEU A 1 237 ? 134.135 167.561 162.178 1.00 52.46  ?  226 LEU A CB  1 
ATOM   1532  C CG  . LEU A 1 237 ? 133.539 167.554 160.774 1.00 52.46  ?  226 LEU A CG  1 
ATOM   1533  C CD1 . LEU A 1 237 ? 132.414 166.549 160.700 1.00 52.46  ?  226 LEU A CD1 1 
ATOM   1534  C CD2 . LEU A 1 237 ? 133.051 168.933 160.386 1.00 52.46  ?  226 LEU A CD2 1 
ATOM   1535  N N   . LYS A 1 238 ? 136.497 167.591 164.454 1.00 52.50  ?  227 LYS A N   1 
ATOM   1536  C CA  . LYS A 1 238 ? 136.862 167.712 165.858 1.00 52.50  ?  227 LYS A CA  1 
ATOM   1537  C C   . LYS A 1 238 ? 137.803 168.876 166.122 1.00 52.50  ?  227 LYS A C   1 
ATOM   1538  O O   . LYS A 1 238 ? 138.065 169.181 167.288 1.00 52.50  ?  227 LYS A O   1 
ATOM   1539  C CB  . LYS A 1 238 ? 137.500 166.417 166.353 1.00 52.50  ?  227 LYS A CB  1 
ATOM   1540  C CG  . LYS A 1 238 ? 138.672 165.952 165.524 1.00 52.50  ?  227 LYS A CG  1 
ATOM   1541  C CD  . LYS A 1 238 ? 139.206 164.625 166.022 1.00 52.50  ?  227 LYS A CD  1 
ATOM   1542  C CE  . LYS A 1 238 ? 140.010 164.796 167.293 1.00 52.50  ?  227 LYS A CE  1 
ATOM   1543  N NZ  . LYS A 1 238 ? 140.661 163.523 167.705 1.00 52.50  1  227 LYS A NZ  1 
ATOM   1544  N N   . PHE A 1 239 ? 138.321 169.520 165.078 1.00 51.61  ?  228 PHE A N   1 
ATOM   1545  C CA  . PHE A 1 239 ? 139.175 170.690 165.222 1.00 51.61  ?  228 PHE A CA  1 
ATOM   1546  C C   . PHE A 1 239 ? 138.471 171.988 164.863 1.00 51.61  ?  228 PHE A C   1 
ATOM   1547  O O   . PHE A 1 239 ? 138.775 173.026 165.456 1.00 51.61  ?  228 PHE A O   1 
ATOM   1548  C CB  . PHE A 1 239 ? 140.431 170.536 164.362 1.00 51.61  ?  228 PHE A CB  1 
ATOM   1549  C CG  . PHE A 1 239 ? 141.276 169.360 164.745 1.00 51.61  ?  228 PHE A CG  1 
ATOM   1550  C CD1 . PHE A 1 239 ? 141.975 169.357 165.934 1.00 51.61  ?  228 PHE A CD1 1 
ATOM   1551  C CD2 . PHE A 1 239 ? 141.356 168.253 163.926 1.00 51.61  ?  228 PHE A CD2 1 
ATOM   1552  C CE1 . PHE A 1 239 ? 142.740 168.277 166.293 1.00 51.61  ?  228 PHE A CE1 1 
ATOM   1553  C CE2 . PHE A 1 239 ? 142.121 167.171 164.281 1.00 51.61  ?  228 PHE A CE2 1 
ATOM   1554  C CZ  . PHE A 1 239 ? 142.812 167.182 165.466 1.00 51.61  ?  228 PHE A CZ  1 
ATOM   1555  N N   . ILE A 1 240 ? 137.541 171.955 163.907 1.00 55.81  ?  229 ILE A N   1 
ATOM   1556  C CA  . ILE A 1 240 ? 136.708 173.122 163.640 1.00 55.81  ?  229 ILE A CA  1 
ATOM   1557  C C   . ILE A 1 240 ? 135.861 173.459 164.856 1.00 55.81  ?  229 ILE A C   1 
ATOM   1558  O O   . ILE A 1 240 ? 135.814 174.613 165.291 1.00 55.81  ?  229 ILE A O   1 
ATOM   1559  C CB  . ILE A 1 240 ? 135.821 172.880 162.402 1.00 55.81  ?  229 ILE A CB  1 
ATOM   1560  C CG1 . ILE A 1 240 ? 136.643 172.338 161.237 1.00 55.81  ?  229 ILE A CG1 1 
ATOM   1561  C CG2 . ILE A 1 240 ? 135.116 174.150 162.001 1.00 55.81  ?  229 ILE A CG2 1 
ATOM   1562  C CD1 . ILE A 1 240 ? 137.513 173.356 160.575 1.00 55.81  ?  229 ILE A CD1 1 
ATOM   1563  N N   . PHE A 1 241 ? 135.181 172.460 165.422 1.00 56.39  ?  230 PHE A N   1 
ATOM   1564  C CA  . PHE A 1 241 ? 134.331 172.652 166.585 1.00 56.39  ?  230 PHE A CA  1 
ATOM   1565  C C   . PHE A 1 241 ? 135.069 172.514 167.907 1.00 56.39  ?  230 PHE A C   1 
ATOM   1566  O O   . PHE A 1 241 ? 134.539 172.948 168.933 1.00 56.39  ?  230 PHE A O   1 
ATOM   1567  C CB  . PHE A 1 241 ? 133.171 171.647 166.569 1.00 56.39  ?  230 PHE A CB  1 
ATOM   1568  C CG  . PHE A 1 241 ? 132.415 171.598 165.269 1.00 56.39  ?  230 PHE A CG  1 
ATOM   1569  C CD1 . PHE A 1 241 ? 131.868 172.741 164.720 1.00 56.39  ?  230 PHE A CD1 1 
ATOM   1570  C CD2 . PHE A 1 241 ? 132.239 170.400 164.604 1.00 56.39  ?  230 PHE A CD2 1 
ATOM   1571  C CE1 . PHE A 1 241 ? 131.174 172.686 163.532 1.00 56.39  ?  230 PHE A CE1 1 
ATOM   1572  C CE2 . PHE A 1 241 ? 131.547 170.346 163.418 1.00 56.39  ?  230 PHE A CE2 1 
ATOM   1573  C CZ  . PHE A 1 241 ? 131.015 171.489 162.883 1.00 56.39  ?  230 PHE A CZ  1 
ATOM   1574  N N   . GLN A 1 242 ? 136.268 171.931 167.907 1.00 59.23  ?  231 GLN A N   1 
ATOM   1575  C CA  . GLN A 1 242 ? 137.053 171.674 169.114 1.00 59.23  ?  231 GLN A CA  1 
ATOM   1576  C C   . GLN A 1 242 ? 136.353 170.707 170.063 1.00 59.23  ?  231 GLN A C   1 
ATOM   1577  O O   . GLN A 1 242 ? 136.044 171.061 171.202 1.00 59.23  ?  231 GLN A O   1 
ATOM   1578  C CB  . GLN A 1 242 ? 137.416 172.966 169.849 1.00 59.23  ?  231 GLN A CB  1 
ATOM   1579  C CG  . GLN A 1 242 ? 138.660 172.848 170.710 1.00 59.23  ?  231 GLN A CG  1 
ATOM   1580  C CD  . GLN A 1 242 ? 138.742 173.920 171.770 1.00 59.23  ?  231 GLN A CD  1 
ATOM   1581  O OE1 . GLN A 1 242 ? 138.163 174.992 171.627 1.00 59.23  ?  231 GLN A OE1 1 
ATOM   1582  N NE2 . GLN A 1 242 ? 139.458 173.633 172.846 1.00 59.23  ?  231 GLN A NE2 1 
ATOM   1583  N N   . LEU A 1 243 ? 136.093 169.490 169.603 1.00 58.08  ?  232 LEU A N   1 
ATOM   1584  C CA  . LEU A 1 243 ? 135.459 168.473 170.422 1.00 58.08  ?  232 LEU A CA  1 
ATOM   1585  C C   . LEU A 1 243 ? 136.414 167.312 170.672 1.00 58.08  ?  232 LEU A C   1 
ATOM   1586  O O   . LEU A 1 243 ? 137.373 167.094 169.932 1.00 58.08  ?  232 LEU A O   1 
ATOM   1587  C CB  . LEU A 1 243 ? 134.183 167.968 169.752 1.00 58.08  ?  232 LEU A CB  1 
ATOM   1588  C CG  . LEU A 1 243 ? 133.246 169.058 169.240 1.00 58.08  ?  232 LEU A CG  1 
ATOM   1589  C CD1 . LEU A 1 243 ? 132.281 168.488 168.230 1.00 58.08  ?  232 LEU A CD1 1 
ATOM   1590  C CD2 . LEU A 1 243 ? 132.506 169.702 170.390 1.00 58.08  ?  232 LEU A CD2 1 
ATOM   1591  N N   . THR A 1 244 ? 136.139 166.565 171.736 1.00 61.07  ?  233 THR A N   1 
ATOM   1592  C CA  . THR A 1 244 ? 136.913 165.380 172.088 1.00 61.07  ?  233 THR A CA  1 
ATOM   1593  C C   . THR A 1 244 ? 136.239 164.164 171.466 1.00 61.07  ?  233 THR A C   1 
ATOM   1594  O O   . THR A 1 244 ? 135.167 163.743 171.911 1.00 61.07  ?  233 THR A O   1 
ATOM   1595  C CB  . THR A 1 244 ? 137.025 165.229 173.601 1.00 61.07  ?  233 THR A CB  1 
ATOM   1596  O OG1 . THR A 1 244 ? 137.769 166.328 174.140 1.00 61.07  ?  233 THR A OG1 1 
ATOM   1597  C CG2 . THR A 1 244 ? 137.728 163.933 173.952 1.00 61.07  ?  233 THR A CG2 1 
ATOM   1598  N N   . VAL A 1 245 ? 136.860 163.609 170.438 1.00 56.94  ?  234 VAL A N   1 
ATOM   1599  C CA  . VAL A 1 245 ? 136.348 162.444 169.723 1.00 56.94  ?  234 VAL A CA  1 
ATOM   1600  C C   . VAL A 1 245 ? 137.298 161.283 169.976 1.00 56.94  ?  234 VAL A C   1 
ATOM   1601  O O   . VAL A 1 245 ? 138.514 161.454 169.838 1.00 56.94  ?  234 VAL A O   1 
ATOM   1602  C CB  . VAL A 1 245 ? 136.211 162.716 168.213 1.00 56.94  ?  234 VAL A CB  1 
ATOM   1603  C CG1 . VAL A 1 245 ? 135.654 161.504 167.504 1.00 56.94  ?  234 VAL A CG1 1 
ATOM   1604  C CG2 . VAL A 1 245 ? 135.332 163.925 167.980 1.00 56.94  ?  234 VAL A CG2 1 
ATOM   1605  N N   . PRO A 1 246 ? 136.802 160.106 170.354 1.00 57.04  ?  235 PRO A N   1 
ATOM   1606  C CA  . PRO A 1 246 ? 137.691 158.960 170.572 1.00 57.04  ?  235 PRO A CA  1 
ATOM   1607  C C   . PRO A 1 246 ? 138.390 158.536 169.291 1.00 57.04  ?  235 PRO A C   1 
ATOM   1608  O O   . PRO A 1 246 ? 138.137 159.044 168.199 1.00 57.04  ?  235 PRO A O   1 
ATOM   1609  C CB  . PRO A 1 246 ? 136.742 157.870 171.073 1.00 57.04  ?  235 PRO A CB  1 
ATOM   1610  C CG  . PRO A 1 246 ? 135.578 158.605 171.624 1.00 57.04  ?  235 PRO A CG  1 
ATOM   1611  C CD  . PRO A 1 246 ? 135.420 159.813 170.764 1.00 57.04  ?  235 PRO A CD  1 
ATOM   1612  N N   . SER A 1 247 ? 139.349 157.631 169.441 1.00 56.79  ?  236 SER A N   1 
ATOM   1613  C CA  . SER A 1 247 ? 140.103 157.151 168.287 1.00 56.79  ?  236 SER A CA  1 
ATOM   1614  C C   . SER A 1 247 ? 139.427 155.931 167.704 1.00 56.79  ?  236 SER A C   1 
ATOM   1615  O O   . SER A 1 247 ? 139.863 154.807 167.933 1.00 56.79  ?  236 SER A O   1 
ATOM   1616  C CB  . SER A 1 247 ? 141.531 156.813 168.695 1.00 56.79  ?  236 SER A CB  1 
ATOM   1617  O OG  . SER A 1 247 ? 142.197 157.943 169.228 1.00 56.79  ?  236 SER A OG  1 
ATOM   1618  N N   . HIS A 1 248 ? 138.372 156.172 166.952 1.00 54.88  ?  237 HIS A N   1 
ATOM   1619  C CA  . HIS A 1 248 ? 137.603 155.121 166.351 1.00 54.88  ?  237 HIS A CA  1 
ATOM   1620  C C   . HIS A 1 248 ? 138.391 154.369 165.307 1.00 54.88  ?  237 HIS A C   1 
ATOM   1621  O O   . HIS A 1 248 ? 139.264 154.906 164.662 1.00 54.88  ?  237 HIS A O   1 
ATOM   1622  C CB  . HIS A 1 248 ? 136.333 155.704 165.760 1.00 54.88  ?  237 HIS A CB  1 
ATOM   1623  C CG  . HIS A 1 248 ? 135.493 156.437 166.754 1.00 54.88  ?  237 HIS A CG  1 
ATOM   1624  N ND1 . HIS A 1 248 ? 134.864 155.806 167.802 1.00 54.88  ?  237 HIS A ND1 1 
ATOM   1625  C CD2 . HIS A 1 248 ? 135.178 157.745 166.861 1.00 54.88  ?  237 HIS A CD2 1 
ATOM   1626  C CE1 . HIS A 1 248 ? 134.189 156.691 168.504 1.00 54.88  ?  237 HIS A CE1 1 
ATOM   1627  N NE2 . HIS A 1 248 ? 134.363 157.875 167.953 1.00 54.88  ?  237 HIS A NE2 1 
ATOM   1628  N N   . THR A 1 249 ? 138.050 153.111 165.130 1.00 57.22  ?  238 THR A N   1 
ATOM   1629  C CA  . THR A 1 249 ? 138.716 152.272 164.162 1.00 57.22  ?  238 THR A CA  1 
ATOM   1630  C C   . THR A 1 249 ? 137.683 151.756 163.184 1.00 57.22  ?  238 THR A C   1 
ATOM   1631  O O   . THR A 1 249 ? 136.490 151.887 163.396 1.00 57.22  ?  238 THR A O   1 
ATOM   1632  C CB  . THR A 1 249 ? 139.468 151.108 164.826 1.00 57.22  ?  238 THR A CB  1 
ATOM   1633  O OG1 . THR A 1 249 ? 138.621 150.461 165.780 1.00 57.22  ?  238 THR A OG1 1 
ATOM   1634  C CG2 . THR A 1 249 ? 140.709 151.611 165.524 1.00 57.22  ?  238 THR A CG2 1 
ATOM   1635  N N   . ASP A 1 250 ? 138.139 151.239 162.063 1.00 56.24  ?  239 ASP A N   1 
ATOM   1636  C CA  . ASP A 1 250 ? 137.220 150.705 161.081 1.00 56.24  ?  239 ASP A CA  1 
ATOM   1637  C C   . ASP A 1 250 ? 136.730 149.315 161.471 1.00 56.24  ?  239 ASP A C   1 
ATOM   1638  O O   . ASP A 1 250 ? 137.395 148.627 162.222 1.00 56.24  ?  239 ASP A O   1 
ATOM   1639  C CB  . ASP A 1 250 ? 137.861 150.753 159.703 1.00 56.24  ?  239 ASP A CB  1 
ATOM   1640  C CG  . ASP A 1 250 ? 137.865 152.142 159.143 1.00 56.24  ?  239 ASP A CG  1 
ATOM   1641  O OD1 . ASP A 1 250 ? 136.789 152.757 159.147 1.00 56.24  ?  239 ASP A OD1 1 
ATOM   1642  O OD2 . ASP A 1 250 ? 138.927 152.627 158.706 1.00 56.24  -1 239 ASP A OD2 1 
ATOM   1643  N N   . PRO A 1 251 ? 135.540 148.912 161.003 1.00 56.98  ?  240 PRO A N   1 
ATOM   1644  C CA  . PRO A 1 251 ? 134.710 149.516 159.956 1.00 56.98  ?  240 PRO A CA  1 
ATOM   1645  C C   . PRO A 1 251 ? 133.887 150.669 160.453 1.00 56.98  ?  240 PRO A C   1 
ATOM   1646  O O   . PRO A 1 251 ? 133.904 150.926 161.630 1.00 56.98  ?  240 PRO A O   1 
ATOM   1647  C CB  . PRO A 1 251 ? 133.786 148.371 159.545 1.00 56.98  ?  240 PRO A CB  1 
ATOM   1648  C CG  . PRO A 1 251 ? 133.676 147.538 160.763 1.00 56.98  ?  240 PRO A CG  1 
ATOM   1649  C CD  . PRO A 1 251 ? 135.022 147.599 161.411 1.00 56.98  ?  240 PRO A CD  1 
ATOM   1650  N N   . VAL A 1 252 ? 133.330 151.434 159.529 1.00 52.56  ?  241 VAL A N   1 
ATOM   1651  C CA  . VAL A 1 252 ? 132.433 152.558 159.789 1.00 52.56  ?  241 VAL A CA  1 
ATOM   1652  C C   . VAL A 1 252 ? 132.940 153.612 160.761 1.00 52.56  ?  241 VAL A C   1 
ATOM   1653  O O   . VAL A 1 252 ? 132.158 154.228 161.436 1.00 52.56  ?  241 VAL A O   1 
ATOM   1654  C CB  . VAL A 1 252 ? 130.965 152.130 160.072 1.00 52.56  ?  241 VAL A CB  1 
ATOM   1655  C CG1 . VAL A 1 252 ? 130.460 151.183 159.006 1.00 52.56  ?  241 VAL A CG1 1 
ATOM   1656  C CG2 . VAL A 1 252 ? 130.762 151.548 161.462 1.00 52.56  ?  241 VAL A CG2 1 
ATOM   1657  N N   . SER A 1 253 ? 134.233 153.880 160.760 1.00 52.24  ?  242 SER A N   1 
ATOM   1658  C CA  . SER A 1 253 ? 134.785 154.874 161.643 1.00 52.24  ?  242 SER A CA  1 
ATOM   1659  C C   . SER A 1 253 ? 134.308 156.275 161.298 1.00 52.24  ?  242 SER A C   1 
ATOM   1660  O O   . SER A 1 253 ? 134.235 157.112 162.170 1.00 52.24  ?  242 SER A O   1 
ATOM   1661  C CB  . SER A 1 253 ? 136.308 154.784 161.714 1.00 52.24  ?  242 SER A CB  1 
ATOM   1662  O OG  . SER A 1 253 ? 136.915 154.923 160.457 1.00 52.24  ?  242 SER A OG  1 
ATOM   1663  N N   . ILE A 1 254 ? 134.004 156.542 160.035 1.00 48.39  ?  243 ILE A N   1 
ATOM   1664  C CA  . ILE A 1 254 ? 133.485 157.849 159.671 1.00 48.39  ?  243 ILE A CA  1 
ATOM   1665  C C   . ILE A 1 254 ? 132.152 158.125 160.353 1.00 48.39  ?  243 ILE A C   1 
ATOM   1666  O O   . ILE A 1 254 ? 131.884 159.251 160.748 1.00 48.39  ?  243 ILE A O   1 
ATOM   1667  C CB  . ILE A 1 254 ? 133.364 157.988 158.133 1.00 48.39  ?  243 ILE A CB  1 
ATOM   1668  C CG1 . ILE A 1 254 ? 133.161 159.448 157.733 1.00 48.39  ?  243 ILE A CG1 1 
ATOM   1669  C CG2 . ILE A 1 254 ? 132.243 157.108 157.594 1.00 48.39  ?  243 ILE A CG2 1 
ATOM   1670  C CD1 . ILE A 1 254 ? 133.334 159.693 156.251 1.00 48.39  ?  243 ILE A CD1 1 
ATOM   1671  N N   . PHE A 1 255 ? 131.320 157.101 160.495 1.00 50.69  ?  244 PHE A N   1 
ATOM   1672  C CA  . PHE A 1 255 ? 130.044 157.260 161.174 1.00 50.69  ?  244 PHE A CA  1 
ATOM   1673  C C   . PHE A 1 255 ? 130.235 157.310 162.677 1.00 50.69  ?  244 PHE A C   1 
ATOM   1674  O O   . PHE A 1 255 ? 129.605 158.115 163.350 1.00 50.69  ?  244 PHE A O   1 
ATOM   1675  C CB  . PHE A 1 255 ? 129.108 156.122 160.788 1.00 50.69  ?  244 PHE A CB  1 
ATOM   1676  C CG  . PHE A 1 255 ? 128.901 155.981 159.311 1.00 50.69  ?  244 PHE A CG  1 
ATOM   1677  C CD1 . PHE A 1 255 ? 128.099 156.873 158.622 1.00 50.69  ?  244 PHE A CD1 1 
ATOM   1678  C CD2 . PHE A 1 255 ? 129.501 154.948 158.613 1.00 50.69  ?  244 PHE A CD2 1 
ATOM   1679  C CE1 . PHE A 1 255 ? 127.904 156.743 157.262 1.00 50.69  ?  244 PHE A CE1 1 
ATOM   1680  C CE2 . PHE A 1 255 ? 129.310 154.811 157.252 1.00 50.69  ?  244 PHE A CE2 1 
ATOM   1681  C CZ  . PHE A 1 255 ? 128.510 155.709 156.576 1.00 50.69  ?  244 PHE A CZ  1 
ATOM   1682  N N   . LYS A 1 256 ? 131.090 156.445 163.212 1.00 51.03  ?  245 LYS A N   1 
ATOM   1683  C CA  . LYS A 1 256 ? 131.394 156.486 164.634 1.00 51.03  ?  245 LYS A CA  1 
ATOM   1684  C C   . LYS A 1 256 ? 131.872 157.872 164.958 1.00 51.03  ?  245 LYS A C   1 
ATOM   1685  O O   . LYS A 1 256 ? 131.553 158.422 166.006 1.00 51.03  ?  245 LYS A O   1 
ATOM   1686  C CB  . LYS A 1 256 ? 132.494 155.497 164.987 1.00 51.03  ?  245 LYS A CB  1 
ATOM   1687  C CG  . LYS A 1 256 ? 132.219 154.051 164.625 1.00 51.03  ?  245 LYS A CG  1 
ATOM   1688  C CD  . LYS A 1 256 ? 133.440 153.200 164.924 1.00 51.03  ?  245 LYS A CD  1 
ATOM   1689  C CE  . LYS A 1 256 ? 133.220 151.746 164.550 1.00 51.03  ?  245 LYS A CE  1 
ATOM   1690  N NZ  . LYS A 1 256 ? 134.431 150.926 164.819 1.00 51.03  1  245 LYS A NZ  1 
ATOM   1691  N N   . VAL A 1 257 ? 132.642 158.446 164.049 1.00 51.15  ?  246 VAL A N   1 
ATOM   1692  C CA  . VAL A 1 257 ? 133.188 159.781 164.258 1.00 51.15  ?  246 VAL A CA  1 
ATOM   1693  C C   . VAL A 1 257 ? 132.111 160.838 164.066 1.00 51.15  ?  246 VAL A C   1 
ATOM   1694  O O   . VAL A 1 257 ? 132.031 161.802 164.833 1.00 51.15  ?  246 VAL A O   1 
ATOM   1695  C CB  . VAL A 1 257 ? 134.384 160.015 163.319 1.00 51.15  ?  246 VAL A CB  1 
ATOM   1696  C CG1 . VAL A 1 257 ? 134.800 161.472 163.338 1.00 51.15  ?  246 VAL A CG1 1 
ATOM   1697  C CG2 . VAL A 1 257 ? 135.541 159.125 163.709 1.00 51.15  ?  246 VAL A CG2 1 
ATOM   1698  N N   . LEU A 1 258 ? 131.283 160.718 163.045 1.00 52.35  ?  247 LEU A N   1 
ATOM   1699  C CA  . LEU A 1 258 ? 130.202 161.686 162.886 1.00 52.35  ?  247 LEU A CA  1 
ATOM   1700  C C   . LEU A 1 258 ? 129.319 161.753 164.126 1.00 52.35  ?  247 LEU A C   1 
ATOM   1701  O O   . LEU A 1 258 ? 128.952 162.835 164.571 1.00 52.35  ?  247 LEU A O   1 
ATOM   1702  C CB  . LEU A 1 258 ? 129.365 161.374 161.647 1.00 52.35  ?  247 LEU A CB  1 
ATOM   1703  C CG  . LEU A 1 258 ? 129.966 161.837 160.324 1.00 52.35  ?  247 LEU A CG  1 
ATOM   1704  C CD1 . LEU A 1 258 ? 129.266 161.175 159.149 1.00 52.35  ?  247 LEU A CD1 1 
ATOM   1705  C CD2 . LEU A 1 258 ? 129.893 163.352 160.223 1.00 52.35  ?  247 LEU A CD2 1 
ATOM   1706  N N   . TYR A 1 259 ? 128.984 160.600 164.686 1.00 54.38  ?  248 TYR A N   1 
ATOM   1707  C CA  . TYR A 1 259 ? 128.165 160.567 165.884 1.00 54.38  ?  248 TYR A CA  1 
ATOM   1708  C C   . TYR A 1 259 ? 128.848 161.247 167.055 1.00 54.38  ?  248 TYR A C   1 
ATOM   1709  O O   . TYR A 1 259 ? 128.241 162.067 167.733 1.00 54.38  ?  248 TYR A O   1 
ATOM   1710  C CB  . TYR A 1 259 ? 127.830 159.131 166.267 1.00 54.38  ?  248 TYR A CB  1 
ATOM   1711  C CG  . TYR A 1 259 ? 127.066 159.051 167.564 1.00 54.38  ?  248 TYR A CG  1 
ATOM   1712  C CD1 . TYR A 1 259 ? 127.687 158.636 168.733 1.00 54.38  ?  248 TYR A CD1 1 
ATOM   1713  C CD2 . TYR A 1 259 ? 125.734 159.424 167.625 1.00 54.38  ?  248 TYR A CD2 1 
ATOM   1714  C CE1 . TYR A 1 259 ? 126.990 158.574 169.924 1.00 54.38  ?  248 TYR A CE1 1 
ATOM   1715  C CE2 . TYR A 1 259 ? 125.030 159.367 168.810 1.00 54.38  ?  248 TYR A CE2 1 
ATOM   1716  C CZ  . TYR A 1 259 ? 125.663 158.942 169.956 1.00 54.38  ?  248 TYR A CZ  1 
ATOM   1717  O OH  . TYR A 1 259 ? 124.963 158.884 171.137 1.00 54.38  ?  248 TYR A OH  1 
ATOM   1718  N N   . SER A 1 260 ? 130.109 160.916 167.290 1.00 54.71  ?  249 SER A N   1 
ATOM   1719  C CA  . SER A 1 260 ? 130.842 161.511 168.395 1.00 54.71  ?  249 SER A CA  1 
ATOM   1720  C C   . SER A 1 260 ? 130.843 163.022 168.296 1.00 54.71  ?  249 SER A C   1 
ATOM   1721  O O   . SER A 1 260 ? 130.708 163.704 169.299 1.00 54.71  ?  249 SER A O   1 
ATOM   1722  C CB  . SER A 1 260 ? 132.279 160.994 168.439 1.00 54.71  ?  249 SER A CB  1 
ATOM   1723  O OG  . SER A 1 260 ? 132.318 159.599 168.675 1.00 54.71  ?  249 SER A OG  1 
ATOM   1724  N N   . VAL A 1 261 ? 130.994 163.549 167.093 1.00 54.77  ?  250 VAL A N   1 
ATOM   1725  C CA  . VAL A 1 261 ? 131.033 164.991 166.914 1.00 54.77  ?  250 VAL A CA  1 
ATOM   1726  C C   . VAL A 1 261 ? 129.681 165.633 167.168 1.00 54.77  ?  250 VAL A C   1 
ATOM   1727  O O   . VAL A 1 261 ? 129.577 166.562 167.962 1.00 54.77  ?  250 VAL A O   1 
ATOM   1728  C CB  . VAL A 1 261 ? 131.503 165.366 165.493 1.00 54.77  ?  250 VAL A CB  1 
ATOM   1729  C CG1 . VAL A 1 261 ? 131.234 166.833 165.203 1.00 54.77  ?  250 VAL A CG1 1 
ATOM   1730  C CG2 . VAL A 1 261 ? 132.973 165.028 165.309 1.00 54.77  ?  250 VAL A CG2 1 
ATOM   1731  N N   . PHE A 1 262 ? 128.639 165.132 166.521 1.00 57.05  ?  251 PHE A N   1 
ATOM   1732  C CA  . PHE A 1 262 ? 127.318 165.754 166.644 1.00 57.05  ?  251 PHE A CA  1 
ATOM   1733  C C   . PHE A 1 262 ? 126.581 165.380 167.925 1.00 57.05  ?  251 PHE A C   1 
ATOM   1734  O O   . PHE A 1 262 ? 125.628 166.050 168.300 1.00 57.05  ?  251 PHE A O   1 
ATOM   1735  C CB  . PHE A 1 262 ? 126.489 165.449 165.398 1.00 57.05  ?  251 PHE A CB  1 
ATOM   1736  C CG  . PHE A 1 262 ? 127.000 166.140 164.172 1.00 57.05  ?  251 PHE A CG  1 
ATOM   1737  C CD1 . PHE A 1 262 ? 126.651 167.453 163.911 1.00 57.05  ?  251 PHE A CD1 1 
ATOM   1738  C CD2 . PHE A 1 262 ? 127.859 165.494 163.302 1.00 57.05  ?  251 PHE A CD2 1 
ATOM   1739  C CE1 . PHE A 1 262 ? 127.131 168.102 162.792 1.00 57.05  ?  251 PHE A CE1 1 
ATOM   1740  C CE2 . PHE A 1 262 ? 128.343 166.136 162.181 1.00 57.05  ?  251 PHE A CE2 1 
ATOM   1741  C CZ  . PHE A 1 262 ? 127.979 167.442 161.925 1.00 57.05  ?  251 PHE A CZ  1 
ATOM   1742  N N   . SER A 1 263 ? 127.014 164.326 168.602 1.00 58.30  ?  252 SER A N   1 
ATOM   1743  C CA  . SER A 1 263 ? 126.422 163.993 169.884 1.00 58.30  ?  252 SER A CA  1 
ATOM   1744  C C   . SER A 1 263 ? 126.769 165.085 170.879 1.00 58.30  ?  252 SER A C   1 
ATOM   1745  O O   . SER A 1 263 ? 126.052 165.292 171.854 1.00 58.30  ?  252 SER A O   1 
ATOM   1746  C CB  . SER A 1 263 ? 126.945 162.660 170.389 1.00 58.30  ?  252 SER A CB  1 
ATOM   1747  O OG  . SER A 1 263 ? 126.459 162.382 171.688 1.00 58.30  ?  252 SER A OG  1 
ATOM   1748  N N   . GLN A 1 264 ? 127.880 165.781 170.648 1.00 60.40  ?  253 GLN A N   1 
ATOM   1749  C CA  . GLN A 1 264 ? 128.273 166.868 171.532 1.00 60.40  ?  253 GLN A CA  1 
ATOM   1750  C C   . GLN A 1 264 ? 128.365 168.202 170.805 1.00 60.40  ?  253 GLN A C   1 
ATOM   1751  O O   . GLN A 1 264 ? 129.196 169.038 171.164 1.00 60.40  ?  253 GLN A O   1 
ATOM   1752  C CB  . GLN A 1 264 ? 129.610 166.561 172.203 1.00 60.40  ?  253 GLN A CB  1 
ATOM   1753  C CG  . GLN A 1 264 ? 130.579 165.805 171.339 1.00 60.40  ?  253 GLN A CG  1 
ATOM   1754  C CD  . GLN A 1 264 ? 131.773 165.309 172.114 1.00 60.40  ?  253 GLN A CD  1 
ATOM   1755  O OE1 . GLN A 1 264 ? 131.808 165.397 173.338 1.00 60.40  ?  253 GLN A OE1 1 
ATOM   1756  N NE2 . GLN A 1 264 ? 132.762 164.783 171.407 1.00 60.40  ?  253 GLN A NE2 1 
ATOM   1757  N N   . ILE A 1 265 ? 127.531 168.417 169.784 1.00 62.22  ?  254 ILE A N   1 
ATOM   1758  C CA  . ILE A 1 265 ? 127.596 169.650 169.012 1.00 62.22  ?  254 ILE A CA  1 
ATOM   1759  C C   . ILE A 1 265 ? 127.185 170.858 169.837 1.00 62.22  ?  254 ILE A C   1 
ATOM   1760  O O   . ILE A 1 265 ? 127.226 171.990 169.343 1.00 62.22  ?  254 ILE A O   1 
ATOM   1761  C CB  . ILE A 1 265 ? 126.733 169.520 167.738 1.00 62.22  ?  254 ILE A CB  1 
ATOM   1762  C CG1 . ILE A 1 265 ? 127.270 170.429 166.629 1.00 62.22  ?  254 ILE A CG1 1 
ATOM   1763  C CG2 . ILE A 1 265 ? 125.277 169.831 168.035 1.00 62.22  ?  254 ILE A CG2 1 
ATOM   1764  C CD1 . ILE A 1 265 ? 128.585 169.977 166.060 1.00 62.22  ?  254 ILE A CD1 1 
ATOM   1765  N N   . GLU A 1 266 ? 126.788 170.654 171.094 1.00 64.46  ?  255 GLU A N   1 
ATOM   1766  C CA  . GLU A 1 266 ? 126.460 171.765 171.977 1.00 64.46  ?  255 GLU A CA  1 
ATOM   1767  C C   . GLU A 1 266 ? 127.689 172.359 172.654 1.00 64.46  ?  255 GLU A C   1 
ATOM   1768  O O   . GLU A 1 266 ? 127.661 173.537 173.022 1.00 64.46  ?  255 GLU A O   1 
ATOM   1769  C CB  . GLU A 1 266 ? 125.449 171.304 173.028 1.00 64.46  ?  255 GLU A CB  1 
ATOM   1770  C CG  . GLU A 1 266 ? 126.023 170.366 174.077 1.00 64.46  ?  255 GLU A CG  1 
ATOM   1771  C CD  . GLU A 1 266 ? 125.714 168.911 173.793 1.00 64.46  ?  255 GLU A CD  1 
ATOM   1772  O OE1 . GLU A 1 266 ? 124.908 168.641 172.879 1.00 64.46  ?  255 GLU A OE1 1 
ATOM   1773  O OE2 . GLU A 1 266 ? 126.278 168.035 174.481 1.00 64.46  -1 255 GLU A OE2 1 
ATOM   1774  N N   . LYS A 1 267 ? 128.758 171.584 172.822 1.00 64.41  ?  256 LYS A N   1 
ATOM   1775  C CA  . LYS A 1 267 ? 129.994 172.065 173.421 1.00 64.41  ?  256 LYS A CA  1 
ATOM   1776  C C   . LYS A 1 267 ? 130.923 172.705 172.400 1.00 64.41  ?  256 LYS A C   1 
ATOM   1777  O O   . LYS A 1 267 ? 132.101 172.921 172.698 1.00 64.41  ?  256 LYS A O   1 
ATOM   1778  C CB  . LYS A 1 267 ? 130.720 170.923 174.131 1.00 64.41  ?  256 LYS A CB  1 
ATOM   1779  C CG  . LYS A 1 267 ? 129.807 169.907 174.787 1.00 64.41  ?  256 LYS A CG  1 
ATOM   1780  C CD  . LYS A 1 267 ? 130.618 168.827 175.473 1.00 64.41  ?  256 LYS A CD  1 
ATOM   1781  C CE  . LYS A 1 267 ? 129.787 167.588 175.733 1.00 64.41  ?  256 LYS A CE  1 
ATOM   1782  N NZ  . LYS A 1 267 ? 130.614 166.475 176.273 1.00 64.41  1  256 LYS A NZ  1 
ATOM   1783  N N   . THR A 1 268 ? 130.423 173.005 171.206 1.00 62.94  ?  257 THR A N   1 
ATOM   1784  C CA  . THR A 1 268 ? 131.245 173.548 170.134 1.00 62.94  ?  257 THR A CA  1 
ATOM   1785  C C   . THR A 1 268 ? 131.808 174.911 170.505 1.00 62.94  ?  257 THR A C   1 
ATOM   1786  O O   . THR A 1 268 ? 131.066 175.803 170.926 1.00 62.94  ?  257 THR A O   1 
ATOM   1787  C CB  . THR A 1 268 ? 130.429 173.642 168.843 1.00 62.94  ?  257 THR A CB  1 
ATOM   1788  O OG1 . THR A 1 268 ? 130.345 172.346 168.240 1.00 62.94  ?  257 THR A OG1 1 
ATOM   1789  C CG2 . THR A 1 268 ? 131.071 174.610 167.866 1.00 62.94  ?  257 THR A CG2 1 
ATOM   1790  N N   . ASN A 1 269 ? 133.121 175.079 170.364 1.00 62.81  ?  258 ASN A N   1 
ATOM   1791  C CA  . ASN A 1 269 ? 133.738 176.385 170.553 1.00 62.81  ?  258 ASN A CA  1 
ATOM   1792  C C   . ASN A 1 269 ? 133.352 177.290 169.392 1.00 62.81  ?  258 ASN A C   1 
ATOM   1793  O O   . ASN A 1 269 ? 133.468 176.896 168.228 1.00 62.81  ?  258 ASN A O   1 
ATOM   1794  C CB  . ASN A 1 269 ? 135.254 176.246 170.651 1.00 62.81  ?  258 ASN A CB  1 
ATOM   1795  C CG  . ASN A 1 269 ? 135.893 177.390 171.401 1.00 62.81  ?  258 ASN A CG  1 
ATOM   1796  O OD1 . ASN A 1 269 ? 135.625 178.554 171.124 1.00 62.81  ?  258 ASN A OD1 1 
ATOM   1797  N ND2 . ASN A 1 269 ? 136.742 177.063 172.361 1.00 62.81  ?  258 ASN A ND2 1 
ATOM   1798  N N   . ILE A 1 270 ? 132.878 178.496 169.703 1.00 64.53  ?  259 ILE A N   1 
ATOM   1799  C CA  . ILE A 1 270 ? 132.422 179.389 168.645 1.00 64.53  ?  259 ILE A CA  1 
ATOM   1800  C C   . ILE A 1 270 ? 133.591 180.141 168.027 1.00 64.53  ?  259 ILE A C   1 
ATOM   1801  O O   . ILE A 1 270 ? 133.579 180.437 166.827 1.00 64.53  ?  259 ILE A O   1 
ATOM   1802  C CB  . ILE A 1 270 ? 131.348 180.352 169.179 1.00 64.53  ?  259 ILE A CB  1 
ATOM   1803  C CG1 . ILE A 1 270 ? 130.376 179.607 170.092 1.00 64.53  ?  259 ILE A CG1 1 
ATOM   1804  C CG2 . ILE A 1 270 ? 130.599 180.998 168.031 1.00 64.53  ?  259 ILE A CG2 1 
ATOM   1805  C CD1 . ILE A 1 270 ? 129.389 178.739 169.349 1.00 64.53  ?  259 ILE A CD1 1 
ATOM   1806  N N   . ALA A 1 271 ? 134.618 180.459 168.818 1.00 63.91  ?  260 ALA A N   1 
ATOM   1807  C CA  . ALA A 1 271 ? 135.786 181.134 168.265 1.00 63.91  ?  260 ALA A CA  1 
ATOM   1808  C C   . ALA A 1 271 ? 136.514 180.242 167.271 1.00 63.91  ?  260 ALA A C   1 
ATOM   1809  O O   . ALA A 1 271 ? 136.929 180.700 166.200 1.00 63.91  ?  260 ALA A O   1 
ATOM   1810  C CB  . ALA A 1 271 ? 136.728 181.566 169.386 1.00 63.91  ?  260 ALA A CB  1 
ATOM   1811  N N   . ASP A 1 272 ? 136.667 178.960 167.602 1.00 62.22  ?  261 ASP A N   1 
ATOM   1812  C CA  . ASP A 1 272 ? 137.303 178.028 166.680 1.00 62.22  ?  261 ASP A CA  1 
ATOM   1813  C C   . ASP A 1 272 ? 136.524 177.927 165.379 1.00 62.22  ?  261 ASP A C   1 
ATOM   1814  O O   . ASP A 1 272 ? 137.103 177.985 164.290 1.00 62.22  ?  261 ASP A O   1 
ATOM   1815  C CB  . ASP A 1 272 ? 137.433 176.652 167.328 1.00 62.22  ?  261 ASP A CB  1 
ATOM   1816  C CG  . ASP A 1 272 ? 138.613 176.561 168.260 1.00 62.22  ?  261 ASP A CG  1 
ATOM   1817  O OD1 . ASP A 1 272 ? 138.971 175.436 168.655 1.00 62.22  ?  261 ASP A OD1 1 
ATOM   1818  O OD2 . ASP A 1 272 ? 139.180 177.614 168.598 1.00 62.22  -1 261 ASP A OD2 1 
ATOM   1819  N N   . LEU A 1 273 ? 135.203 177.769 165.474 1.00 61.66  ?  262 LEU A N   1 
ATOM   1820  C CA  . LEU A 1 273 ? 134.386 177.614 164.276 1.00 61.66  ?  262 LEU A CA  1 
ATOM   1821  C C   . LEU A 1 273 ? 134.425 178.869 163.417 1.00 61.66  ?  262 LEU A C   1 
ATOM   1822  O O   . LEU A 1 273 ? 134.545 178.791 162.192 1.00 61.66  ?  262 LEU A O   1 
ATOM   1823  C CB  . LEU A 1 273 ? 132.949 177.268 164.665 1.00 61.66  ?  262 LEU A CB  1 
ATOM   1824  C CG  . LEU A 1 273 ? 131.918 177.260 163.539 1.00 61.66  ?  262 LEU A CG  1 
ATOM   1825  C CD1 . LEU A 1 273 ? 132.112 176.056 162.642 1.00 61.66  ?  262 LEU A CD1 1 
ATOM   1826  C CD2 . LEU A 1 273 ? 130.516 177.280 164.112 1.00 61.66  ?  262 LEU A CD2 1 
ATOM   1827  N N   . VAL A 1 274 ? 134.341 180.041 164.049 1.00 61.82  ?  263 VAL A N   1 
ATOM   1828  C CA  . VAL A 1 274 ? 134.363 181.289 163.295 1.00 61.82  ?  263 VAL A CA  1 
ATOM   1829  C C   . VAL A 1 274 ? 135.708 181.479 162.603 1.00 61.82  ?  263 VAL A C   1 
ATOM   1830  O O   . VAL A 1 274 ? 135.765 181.859 161.425 1.00 61.82  ?  263 VAL A O   1 
ATOM   1831  C CB  . VAL A 1 274 ? 134.026 182.472 164.218 1.00 61.82  ?  263 VAL A CB  1 
ATOM   1832  C CG1 . VAL A 1 274 ? 134.395 183.783 163.553 1.00 61.82  ?  263 VAL A CG1 1 
ATOM   1833  C CG2 . VAL A 1 274 ? 132.553 182.452 164.571 1.00 61.82  ?  263 VAL A CG2 1 
ATOM   1834  N N   . THR A 1 275 ? 136.810 181.220 163.313 1.00 62.24  ?  264 THR A N   1 
ATOM   1835  C CA  . THR A 1 275 ? 138.125 181.392 162.706 1.00 62.24  ?  264 THR A CA  1 
ATOM   1836  C C   . THR A 1 275 ? 138.344 180.402 161.572 1.00 62.24  ?  264 THR A C   1 
ATOM   1837  O O   . THR A 1 275 ? 138.889 180.759 160.521 1.00 62.24  ?  264 THR A O   1 
ATOM   1838  C CB  . THR A 1 275 ? 139.214 181.245 163.765 1.00 62.24  ?  264 THR A CB  1 
ATOM   1839  O OG1 . THR A 1 275 ? 138.869 182.027 164.914 1.00 62.24  ?  264 THR A OG1 1 
ATOM   1840  C CG2 . THR A 1 275 ? 140.543 181.724 163.216 1.00 62.24  ?  264 THR A CG2 1 
ATOM   1841  N N   . ALA A 1 276 ? 137.911 179.155 161.758 1.00 60.68  ?  265 ALA A N   1 
ATOM   1842  C CA  . ALA A 1 276 ? 138.040 178.162 160.702 1.00 60.68  ?  265 ALA A CA  1 
ATOM   1843  C C   . ALA A 1 276 ? 137.210 178.540 159.484 1.00 60.68  ?  265 ALA A C   1 
ATOM   1844  O O   . ALA A 1 276 ? 137.664 178.390 158.346 1.00 60.68  ?  265 ALA A O   1 
ATOM   1845  C CB  . ALA A 1 276 ? 137.627 176.792 161.226 1.00 60.68  ?  265 ALA A CB  1 
ATOM   1846  N N   . LEU A 1 277 ? 136.018 179.081 159.707 1.00 62.03  ?  266 LEU A N   1 
ATOM   1847  C CA  . LEU A 1 277 ? 135.146 179.469 158.602 1.00 62.03  ?  266 LEU A CA  1 
ATOM   1848  C C   . LEU A 1 277 ? 135.698 180.618 157.791 1.00 62.03  ?  266 LEU A C   1 
ATOM   1849  O O   . LEU A 1 277 ? 135.704 180.569 156.563 1.00 62.03  ?  266 LEU A O   1 
ATOM   1850  C CB  . LEU A 1 277 ? 133.766 179.847 159.125 1.00 62.03  ?  266 LEU A CB  1 
ATOM   1851  C CG  . LEU A 1 277 ? 132.920 178.690 159.652 1.00 62.03  ?  266 LEU A CG  1 
ATOM   1852  C CD1 . LEU A 1 277 ? 131.610 179.203 160.229 1.00 62.03  ?  266 LEU A CD1 1 
ATOM   1853  C CD2 . LEU A 1 277 ? 132.669 177.676 158.548 1.00 62.03  ?  266 LEU A CD2 1 
ATOM   1854  N N   . ILE A 1 278 ? 136.156 181.658 158.470 1.00 63.20  ?  267 ILE A N   1 
ATOM   1855  C CA  . ILE A 1 278 ? 136.682 182.816 157.778 1.00 63.20  ?  267 ILE A CA  1 
ATOM   1856  C C   . ILE A 1 278 ? 137.881 182.432 156.938 1.00 63.20  ?  267 ILE A C   1 
ATOM   1857  O O   . ILE A 1 278 ? 137.997 182.846 155.789 1.00 63.20  ?  267 ILE A O   1 
ATOM   1858  C CB  . ILE A 1 278 ? 137.084 183.912 158.774 1.00 63.20  ?  267 ILE A CB  1 
ATOM   1859  C CG1 . ILE A 1 278 ? 135.854 184.421 159.525 1.00 63.20  ?  267 ILE A CG1 1 
ATOM   1860  C CG2 . ILE A 1 278 ? 137.779 185.057 158.056 1.00 63.20  ?  267 ILE A CG2 1 
ATOM   1861  C CD1 . ILE A 1 278 ? 136.167 185.462 160.575 1.00 63.20  ?  267 ILE A CD1 1 
ATOM   1862  N N   . VAL A 1 279 ? 138.771 181.627 157.503 1.00 63.00  ?  268 VAL A N   1 
ATOM   1863  C CA  . VAL A 1 279 ? 139.961 181.207 156.780 1.00 63.00  ?  268 VAL A CA  1 
ATOM   1864  C C   . VAL A 1 279 ? 139.583 180.418 155.539 1.00 63.00  ?  268 VAL A C   1 
ATOM   1865  O O   . VAL A 1 279 ? 140.092 180.680 154.457 1.00 63.00  ?  268 VAL A O   1 
ATOM   1866  C CB  . VAL A 1 279 ? 140.901 180.376 157.675 1.00 63.00  ?  268 VAL A CB  1 
ATOM   1867  C CG1 . VAL A 1 279 ? 141.990 179.714 156.844 1.00 63.00  ?  268 VAL A CG1 1 
ATOM   1868  C CG2 . VAL A 1 279 ? 141.503 181.247 158.764 1.00 63.00  ?  268 VAL A CG2 1 
ATOM   1869  N N   . LEU A 1 280 ? 138.662 179.477 155.687 1.00 63.58  ?  269 LEU A N   1 
ATOM   1870  C CA  . LEU A 1 280 ? 138.251 178.663 154.556 1.00 63.58  ?  269 LEU A CA  1 
ATOM   1871  C C   . LEU A 1 280 ? 137.687 179.544 153.455 1.00 63.58  ?  269 LEU A C   1 
ATOM   1872  O O   . LEU A 1 280 ? 138.028 179.379 152.287 1.00 63.58  ?  269 LEU A O   1 
ATOM   1873  C CB  . LEU A 1 280 ? 137.231 177.614 154.996 1.00 63.58  ?  269 LEU A CB  1 
ATOM   1874  C CG  . LEU A 1 280 ? 136.750 176.632 153.931 1.00 63.58  ?  269 LEU A CG  1 
ATOM   1875  C CD1 . LEU A 1 280 ? 137.930 175.874 153.347 1.00 63.58  ?  269 LEU A CD1 1 
ATOM   1876  C CD2 . LEU A 1 280 ? 135.735 175.671 154.528 1.00 63.58  ?  269 LEU A CD2 1 
ATOM   1877  N N   . LEU A 1 281 ? 136.847 180.500 153.823 1.00 67.22  ?  270 LEU A N   1 
ATOM   1878  C CA  . LEU A 1 281 ? 136.274 181.404 152.842 1.00 67.22  ?  270 LEU A CA  1 
ATOM   1879  C C   . LEU A 1 281 ? 137.349 182.164 152.082 1.00 67.22  ?  270 LEU A C   1 
ATOM   1880  O O   . LEU A 1 281 ? 137.363 182.156 150.854 1.00 67.22  ?  270 LEU A O   1 
ATOM   1881  C CB  . LEU A 1 281 ? 135.342 182.392 153.531 1.00 67.22  ?  270 LEU A CB  1 
ATOM   1882  C CG  . LEU A 1 281 ? 134.788 183.518 152.660 1.00 67.22  ?  270 LEU A CG  1 
ATOM   1883  C CD1 . LEU A 1 281 ? 133.973 182.952 151.509 1.00 67.22  ?  270 LEU A CD1 1 
ATOM   1884  C CD2 . LEU A 1 281 ? 133.948 184.466 153.500 1.00 67.22  ?  270 LEU A CD2 1 
ATOM   1885  N N   . VAL A 1 282 ? 138.267 182.795 152.801 1.00 66.46  ?  271 VAL A N   1 
ATOM   1886  C CA  . VAL A 1 282 ? 139.317 183.575 152.156 1.00 66.46  ?  271 VAL A CA  1 
ATOM   1887  C C   . VAL A 1 282 ? 140.206 182.729 151.257 1.00 66.46  ?  271 VAL A C   1 
ATOM   1888  O O   . VAL A 1 282 ? 140.441 183.085 150.108 1.00 66.46  ?  271 VAL A O   1 
ATOM   1889  C CB  . VAL A 1 282 ? 140.200 184.290 153.194 1.00 66.46  ?  271 VAL A CB  1 
ATOM   1890  C CG1 . VAL A 1 282 ? 141.354 185.002 152.508 1.00 66.46  ?  271 VAL A CG1 1 
ATOM   1891  C CG2 . VAL A 1 282 ? 139.372 185.260 154.017 1.00 66.46  ?  271 VAL A CG2 1 
ATOM   1892  N N   . VAL A 1 283 ? 140.687 181.603 151.762 1.00 68.09  ?  272 VAL A N   1 
ATOM   1893  C CA  . VAL A 1 283 ? 141.595 180.785 150.972 1.00 68.09  ?  272 VAL A CA  1 
ATOM   1894  C C   . VAL A 1 283 ? 140.897 180.295 149.717 1.00 68.09  ?  272 VAL A C   1 
ATOM   1895  O O   . VAL A 1 283 ? 141.489 180.280 148.645 1.00 68.09  ?  272 VAL A O   1 
ATOM   1896  C CB  . VAL A 1 283 ? 142.166 179.593 151.772 1.00 68.09  ?  272 VAL A CB  1 
ATOM   1897  C CG1 . VAL A 1 283 ? 143.021 180.089 152.927 1.00 68.09  ?  272 VAL A CG1 1 
ATOM   1898  C CG2 . VAL A 1 283 ? 141.056 178.682 152.267 1.00 68.09  ?  272 VAL A CG2 1 
ATOM   1899  N N   . SER A 1 284 ? 139.632 179.918 149.843 1.00 69.96  ?  273 SER A N   1 
ATOM   1900  C CA  . SER A 1 284 ? 138.883 179.428 148.696 1.00 69.96  ?  273 SER A CA  1 
ATOM   1901  C C   . SER A 1 284 ? 138.803 180.492 147.622 1.00 69.96  ?  273 SER A C   1 
ATOM   1902  O O   . SER A 1 284 ? 139.093 180.228 146.457 1.00 69.96  ?  273 SER A O   1 
ATOM   1903  C CB  . SER A 1 284 ? 137.483 179.002 149.120 1.00 69.96  ?  273 SER A CB  1 
ATOM   1904  O OG  . SER A 1 284 ? 137.540 177.966 150.083 1.00 69.96  ?  273 SER A OG  1 
ATOM   1905  N N   . ILE A 1 285 ? 138.444 181.704 148.013 1.00 71.95  ?  274 ILE A N   1 
ATOM   1906  C CA  . ILE A 1 285 ? 138.352 182.790 147.057 1.00 71.95  ?  274 ILE A CA  1 
ATOM   1907  C C   . ILE A 1 285 ? 139.682 183.045 146.374 1.00 71.95  ?  274 ILE A C   1 
ATOM   1908  O O   . ILE A 1 285 ? 139.740 183.130 145.155 1.00 71.95  ?  274 ILE A O   1 
ATOM   1909  C CB  . ILE A 1 285 ? 137.899 184.088 147.741 1.00 71.95  ?  274 ILE A CB  1 
ATOM   1910  C CG1 . ILE A 1 285 ? 136.516 183.900 148.364 1.00 71.95  ?  274 ILE A CG1 1 
ATOM   1911  C CG2 . ILE A 1 285 ? 137.894 185.240 146.750 1.00 71.95  ?  274 ILE A CG2 1 
ATOM   1912  C CD1 . ILE A 1 285 ? 136.033 185.094 149.156 1.00 71.95  ?  274 ILE A CD1 1 
ATOM   1913  N N   . VAL A 1 286 ? 140.753 183.157 147.149 1.00 73.25  ?  275 VAL A N   1 
ATOM   1914  C CA  . VAL A 1 286 ? 142.062 183.471 146.578 1.00 73.25  ?  275 VAL A CA  1 
ATOM   1915  C C   . VAL A 1 286 ? 142.589 182.338 145.707 1.00 73.25  ?  275 VAL A C   1 
ATOM   1916  O O   . VAL A 1 286 ? 143.224 182.586 144.690 1.00 73.25  ?  275 VAL A O   1 
ATOM   1917  C CB  . VAL A 1 286 ? 143.085 183.806 147.677 1.00 73.25  ?  275 VAL A CB  1 
ATOM   1918  C CG1 . VAL A 1 286 ? 144.450 184.095 147.073 1.00 73.25  ?  275 VAL A CG1 1 
ATOM   1919  C CG2 . VAL A 1 286 ? 142.598 184.986 148.503 1.00 73.25  ?  275 VAL A CG2 1 
ATOM   1920  N N   . LYS A 1 287 ? 142.335 181.099 146.098 1.00 75.60  ?  276 LYS A N   1 
ATOM   1921  C CA  . LYS A 1 287 ? 142.752 179.976 145.276 1.00 75.60  ?  276 LYS A CA  1 
ATOM   1922  C C   . LYS A 1 287 ? 142.070 180.086 143.938 1.00 75.60  ?  276 LYS A C   1 
ATOM   1923  O O   . LYS A 1 287 ? 142.669 179.794 142.907 1.00 75.60  ?  276 LYS A O   1 
ATOM   1924  C CB  . LYS A 1 287 ? 142.411 178.645 145.938 1.00 75.60  ?  276 LYS A CB  1 
ATOM   1925  C CG  . LYS A 1 287 ? 143.303 178.292 147.116 1.00 75.60  ?  276 LYS A CG  1 
ATOM   1926  C CD  . LYS A 1 287 ? 142.901 176.959 147.724 1.00 75.60  ?  276 LYS A CD  1 
ATOM   1927  C CE  . LYS A 1 287 ? 143.832 176.566 148.860 1.00 75.60  ?  276 LYS A CE  1 
ATOM   1928  N NZ  . LYS A 1 287 ? 143.475 175.241 149.435 1.00 75.60  1  276 LYS A NZ  1 
ATOM   1929  N N   . GLU A 1 288 ? 140.811 180.499 143.939 1.00 80.14  ?  277 GLU A N   1 
ATOM   1930  C CA  . GLU A 1 288 ? 140.116 180.707 142.682 1.00 80.14  ?  277 GLU A CA  1 
ATOM   1931  C C   . GLU A 1 288 ? 140.769 181.862 141.963 1.00 80.14  ?  277 GLU A C   1 
ATOM   1932  O O   . GLU A 1 288 ? 141.198 181.722 140.824 1.00 80.14  ?  277 GLU A O   1 
ATOM   1933  C CB  . GLU A 1 288 ? 138.640 180.997 142.923 1.00 80.14  ?  277 GLU A CB  1 
ATOM   1934  C CG  . GLU A 1 288 ? 137.886 179.842 143.556 1.00 80.14  ?  277 GLU A CG  1 
ATOM   1935  C CD  . GLU A 1 288 ? 137.837 178.619 142.663 1.00 80.14  ?  277 GLU A CD  1 
ATOM   1936  O OE1 . GLU A 1 288 ? 137.531 177.523 143.175 1.00 80.14  ?  277 GLU A OE1 1 
ATOM   1937  O OE2 . GLU A 1 288 ? 138.103 178.752 141.450 1.00 80.14  -1 277 GLU A OE2 1 
ATOM   1938  N N   . ILE A 1 289 ? 140.869 183.001 142.634 1.00 79.93  ?  278 ILE A N   1 
ATOM   1939  C CA  . ILE A 1 289 ? 141.554 184.129 142.037 1.00 79.93  ?  278 ILE A CA  1 
ATOM   1940  C C   . ILE A 1 289 ? 142.856 183.636 141.461 1.00 79.93  ?  278 ILE A C   1 
ATOM   1941  O O   . ILE A 1 289 ? 143.265 184.052 140.382 1.00 79.93  ?  278 ILE A O   1 
ATOM   1942  C CB  . ILE A 1 289 ? 141.858 185.230 143.056 1.00 79.93  ?  278 ILE A CB  1 
ATOM   1943  C CG1 . ILE A 1 289 ? 140.558 185.811 143.608 1.00 79.93  ?  278 ILE A CG1 1 
ATOM   1944  C CG2 . ILE A 1 289 ? 142.701 186.324 142.422 1.00 79.93  ?  278 ILE A CG2 1 
ATOM   1945  C CD1 . ILE A 1 289 ? 140.768 186.884 144.651 1.00 79.93  ?  278 ILE A CD1 1 
ATOM   1946  N N   . ASN A 1 290 ? 143.517 182.734 142.178 1.00 81.41  ?  279 ASN A N   1 
ATOM   1947  C CA  . ASN A 1 290 ? 144.819 182.292 141.694 1.00 81.41  ?  279 ASN A CA  1 
ATOM   1948  C C   . ASN A 1 290 ? 144.696 181.571 140.365 1.00 81.41  ?  279 ASN A C   1 
ATOM   1949  O O   . ASN A 1 290 ? 145.425 181.874 139.415 1.00 81.41  ?  279 ASN A O   1 
ATOM   1950  C CB  . ASN A 1 290 ? 145.482 181.374 142.721 1.00 81.41  ?  279 ASN A CB  1 
ATOM   1951  C CG  . ASN A 1 290 ? 146.387 182.115 143.671 1.00 81.41  ?  279 ASN A CG  1 
ATOM   1952  O OD1 . ASN A 1 290 ? 146.932 181.529 144.604 1.00 81.41  ?  279 ASN A OD1 1 
ATOM   1953  N ND2 . ASN A 1 290 ? 146.557 183.409 143.443 1.00 81.41  ?  279 ASN A ND2 1 
ATOM   1954  N N   . GLN A 1 291 ? 143.781 180.606 140.279 1.00 87.30  ?  280 GLN A N   1 
ATOM   1955  C CA  . GLN A 1 291 ? 143.713 179.801 139.062 1.00 87.30  ?  280 GLN A CA  1 
ATOM   1956  C C   . GLN A 1 291 ? 142.975 180.537 137.946 1.00 87.30  ?  280 GLN A C   1 
ATOM   1957  O O   . GLN A 1 291 ? 143.195 180.261 136.761 1.00 87.30  ?  280 GLN A O   1 
ATOM   1958  C CB  . GLN A 1 291 ? 143.071 178.445 139.352 1.00 87.30  ?  280 GLN A CB  1 
ATOM   1959  C CG  . GLN A 1 291 ? 143.182 177.470 138.190 1.00 87.30  ?  280 GLN A CG  1 
ATOM   1960  C CD  . GLN A 1 291 ? 142.598 176.111 138.502 1.00 87.30  ?  280 GLN A CD  1 
ATOM   1961  O OE1 . GLN A 1 291 ? 141.940 175.926 139.525 1.00 87.30  ?  280 GLN A OE1 1 
ATOM   1962  N NE2 . GLN A 1 291 ? 142.847 175.146 137.626 1.00 87.30  ?  280 GLN A NE2 1 
ATOM   1963  N N   . ARG A 1 292 ? 142.102 181.486 138.299 1.00 86.82  ?  281 ARG A N   1 
ATOM   1964  C CA  . ARG A 1 292 ? 141.435 182.285 137.275 1.00 86.82  ?  281 ARG A CA  1 
ATOM   1965  C C   . ARG A 1 292 ? 142.392 183.263 136.603 1.00 86.82  ?  281 ARG A C   1 
ATOM   1966  O O   . ARG A 1 292 ? 142.308 183.475 135.389 1.00 86.82  ?  281 ARG A O   1 
ATOM   1967  C CB  . ARG A 1 292 ? 140.257 183.053 137.874 1.00 86.82  ?  281 ARG A CB  1 
ATOM   1968  C CG  . ARG A 1 292 ? 139.060 182.205 138.281 1.00 86.82  ?  281 ARG A CG  1 
ATOM   1969  C CD  . ARG A 1 292 ? 138.490 181.407 137.127 1.00 86.82  ?  281 ARG A CD  1 
ATOM   1970  N NE  . ARG A 1 292 ? 137.598 180.354 137.603 1.00 86.82  ?  281 ARG A NE  1 
ATOM   1971  C CZ  . ARG A 1 292 ? 137.114 179.379 136.841 1.00 86.82  ?  281 ARG A CZ  1 
ATOM   1972  N NH1 . ARG A 1 292 ? 136.310 178.464 137.365 1.00 86.82  1  281 ARG A NH1 1 
ATOM   1973  N NH2 . ARG A 1 292 ? 137.431 179.320 135.556 1.00 86.82  ?  281 ARG A NH2 1 
ATOM   1974  N N   . PHE A 1 293 ? 143.302 183.862 137.365 1.00 87.94  ?  282 PHE A N   1 
ATOM   1975  C CA  . PHE A 1 293 ? 144.170 184.936 136.890 1.00 87.94  ?  282 PHE A CA  1 
ATOM   1976  C C   . PHE A 1 293 ? 145.627 184.504 136.902 1.00 87.94  ?  282 PHE A C   1 
ATOM   1977  O O   . PHE A 1 293 ? 146.507 185.246 137.345 1.00 87.94  ?  282 PHE A O   1 
ATOM   1978  C CB  . PHE A 1 293 ? 143.995 186.200 137.730 1.00 87.94  ?  282 PHE A CB  1 
ATOM   1979  C CG  . PHE A 1 293 ? 142.590 186.728 137.757 1.00 87.94  ?  282 PHE A CG  1 
ATOM   1980  C CD1 . PHE A 1 293 ? 141.648 186.190 138.618 1.00 87.94  ?  282 PHE A CD1 1 
ATOM   1981  C CD2 . PHE A 1 293 ? 142.213 187.773 136.934 1.00 87.94  ?  282 PHE A CD2 1 
ATOM   1982  C CE1 . PHE A 1 293 ? 140.358 186.674 138.648 1.00 87.94  ?  282 PHE A CE1 1 
ATOM   1983  C CE2 . PHE A 1 293 ? 140.924 188.264 136.960 1.00 87.94  ?  282 PHE A CE2 1 
ATOM   1984  C CZ  . PHE A 1 293 ? 139.996 187.714 137.820 1.00 87.94  ?  282 PHE A CZ  1 
ATOM   1985  N N   . LYS A 1 294 ? 145.906 183.291 136.419 1.00 89.36  ?  283 LYS A N   1 
ATOM   1986  C CA  . LYS A 1 294 ? 147.268 182.766 136.439 1.00 89.36  ?  283 LYS A CA  1 
ATOM   1987  C C   . LYS A 1 294 ? 148.246 183.649 135.672 1.00 89.36  ?  283 LYS A C   1 
ATOM   1988  O O   . LYS A 1 294 ? 149.421 183.759 136.037 1.00 89.36  ?  283 LYS A O   1 
ATOM   1989  C CB  . LYS A 1 294 ? 147.285 181.349 135.869 1.00 89.36  ?  283 LYS A CB  1 
ATOM   1990  C CG  . LYS A 1 294 ? 146.964 180.270 136.878 1.00 89.36  ?  283 LYS A CG  1 
ATOM   1991  C CD  . LYS A 1 294 ? 146.939 178.905 136.219 1.00 89.36  ?  283 LYS A CD  1 
ATOM   1992  C CE  . LYS A 1 294 ? 148.218 178.642 135.453 1.00 89.36  ?  283 LYS A CE  1 
ATOM   1993  N NZ  . LYS A 1 294 ? 148.129 177.395 134.649 1.00 89.36  1  283 LYS A NZ  1 
ATOM   1994  N N   . ASP A 1 295 ? 147.778 184.288 134.599 1.00 92.56  ?  284 ASP A N   1 
ATOM   1995  C CA  . ASP A 1 295 ? 148.683 185.042 133.737 1.00 92.56  ?  284 ASP A CA  1 
ATOM   1996  C C   . ASP A 1 295 ? 149.120 186.347 134.394 1.00 92.56  ?  284 ASP A C   1 
ATOM   1997  O O   . ASP A 1 295 ? 150.314 186.670 134.416 1.00 92.56  ?  284 ASP A O   1 
ATOM   1998  C CB  . ASP A 1 295 ? 148.016 185.312 132.390 1.00 92.56  ?  284 ASP A CB  1 
ATOM   1999  C CG  . ASP A 1 295 ? 147.886 184.060 131.545 1.00 92.56  ?  284 ASP A CG  1 
ATOM   2000  O OD1 . ASP A 1 295 ? 148.553 183.054 131.863 1.00 92.56  ?  284 ASP A OD1 1 
ATOM   2001  O OD2 . ASP A 1 295 ? 147.120 184.085 130.561 1.00 92.56  -1 284 ASP A OD2 1 
ATOM   2002  N N   . LYS A 1 296 ? 148.168 187.115 134.931 1.00 91.30  ?  285 LYS A N   1 
ATOM   2003  C CA  . LYS A 1 296 ? 148.501 188.422 135.490 1.00 91.30  ?  285 LYS A CA  1 
ATOM   2004  C C   . LYS A 1 296 ? 149.394 188.296 136.719 1.00 91.30  ?  285 LYS A C   1 
ATOM   2005  O O   . LYS A 1 296 ? 150.173 189.209 137.016 1.00 91.30  ?  285 LYS A O   1 
ATOM   2006  C CB  . LYS A 1 296 ? 147.210 189.188 135.815 1.00 91.30  ?  285 LYS A CB  1 
ATOM   2007  N N   . LEU A 1 297 ? 149.313 187.177 137.430 1.00 88.60  ?  286 LEU A N   1 
ATOM   2008  C CA  . LEU A 1 297 ? 150.145 187.019 138.616 1.00 88.60  ?  286 LEU A CA  1 
ATOM   2009  C C   . LEU A 1 297 ? 151.485 186.416 138.240 1.00 88.60  ?  286 LEU A C   1 
ATOM   2010  O O   . LEU A 1 297 ? 151.522 185.327 137.649 1.00 88.60  ?  286 LEU A O   1 
ATOM   2011  C CB  . LEU A 1 297 ? 149.453 186.130 139.647 1.00 88.60  ?  286 LEU A CB  1 
ATOM   2012  C CG  . LEU A 1 297 ? 148.009 186.470 140.007 1.00 88.60  ?  286 LEU A CG  1 
ATOM   2013  C CD1 . LEU A 1 297 ? 147.345 185.289 140.688 1.00 88.60  ?  286 LEU A CD1 1 
ATOM   2014  C CD2 . LEU A 1 297 ? 147.959 187.699 140.896 1.00 88.60  ?  286 LEU A CD2 1 
ATOM   2015  N N   . PRO A 1 298 ? 152.598 187.080 138.558 1.00 85.79  ?  287 PRO A N   1 
ATOM   2016  C CA  . PRO A 1 298 ? 153.907 186.455 138.303 1.00 85.79  ?  287 PRO A CA  1 
ATOM   2017  C C   . PRO A 1 298 ? 154.131 185.217 139.152 1.00 85.79  ?  287 PRO A C   1 
ATOM   2018  O O   . PRO A 1 298 ? 154.742 184.244 138.692 1.00 85.79  ?  287 PRO A O   1 
ATOM   2019  C CB  . PRO A 1 298 ? 154.895 187.579 138.639 1.00 85.79  ?  287 PRO A CB  1 
ATOM   2020  C CG  . PRO A 1 298 ? 154.163 188.441 139.610 1.00 85.79  ?  287 PRO A CG  1 
ATOM   2021  C CD  . PRO A 1 298 ? 152.723 188.402 139.196 1.00 85.79  ?  287 PRO A CD  1 
ATOM   2022  N N   . VAL A 1 299 ? 153.647 185.233 140.387 1.00 83.03  ?  288 VAL A N   1 
ATOM   2023  C CA  . VAL A 1 299 ? 153.711 184.087 141.288 1.00 83.03  ?  288 VAL A CA  1 
ATOM   2024  C C   . VAL A 1 299 ? 152.334 183.953 141.928 1.00 83.03  ?  288 VAL A C   1 
ATOM   2025  O O   . VAL A 1 299 ? 151.658 184.971 142.142 1.00 83.03  ?  288 VAL A O   1 
ATOM   2026  C CB  . VAL A 1 299 ? 154.832 184.262 142.327 1.00 83.03  ?  288 VAL A CB  1 
ATOM   2027  C CG1 . VAL A 1 299 ? 154.463 185.318 143.360 1.00 83.03  ?  288 VAL A CG1 1 
ATOM   2028  C CG2 . VAL A 1 299 ? 155.166 182.943 142.997 1.00 83.03  ?  288 VAL A CG2 1 
ATOM   2029  N N   . PRO A 1 300 ? 151.849 182.744 142.199 1.00 78.65  ?  289 PRO A N   1 
ATOM   2030  C CA  . PRO A 1 300 ? 150.568 182.621 142.904 1.00 78.65  ?  289 PRO A CA  1 
ATOM   2031  C C   . PRO A 1 300 ? 150.631 183.265 144.280 1.00 78.65  ?  289 PRO A C   1 
ATOM   2032  O O   . PRO A 1 300 ? 151.655 183.217 144.963 1.00 78.65  ?  289 PRO A O   1 
ATOM   2033  C CB  . PRO A 1 300 ? 150.354 181.105 142.998 1.00 78.65  ?  289 PRO A CB  1 
ATOM   2034  C CG  . PRO A 1 300 ? 151.656 180.483 142.608 1.00 78.65  ?  289 PRO A CG  1 
ATOM   2035  C CD  . PRO A 1 300 ? 152.314 181.447 141.688 1.00 78.65  ?  289 PRO A CD  1 
ATOM   2036  N N   . ILE A 1 301 ? 149.523 183.881 144.675 1.00 76.51  ?  290 ILE A N   1 
ATOM   2037  C CA  . ILE A 1 301 ? 149.414 184.551 145.968 1.00 76.51  ?  290 ILE A CA  1 
ATOM   2038  C C   . ILE A 1 301 ? 149.522 183.510 147.074 1.00 76.51  ?  290 ILE A C   1 
ATOM   2039  O O   . ILE A 1 301 ? 148.688 182.596 147.142 1.00 76.51  ?  290 ILE A O   1 
ATOM   2040  C CB  . ILE A 1 301 ? 148.096 185.333 146.078 1.00 76.51  ?  290 ILE A CB  1 
ATOM   2041  C CG1 . ILE A 1 301 ? 148.039 186.439 145.027 1.00 76.51  ?  290 ILE A CG1 1 
ATOM   2042  C CG2 . ILE A 1 301 ? 147.929 185.908 147.476 1.00 76.51  ?  290 ILE A CG2 1 
ATOM   2043  C CD1 . ILE A 1 301 ? 146.724 187.176 144.999 1.00 76.51  ?  290 ILE A CD1 1 
ATOM   2044  N N   . PRO A 1 302 ? 150.520 183.596 147.957 1.00 73.33  ?  291 PRO A N   1 
ATOM   2045  C CA  . PRO A 1 302 ? 150.583 182.647 149.072 1.00 73.33  ?  291 PRO A CA  1 
ATOM   2046  C C   . PRO A 1 302 ? 149.510 182.959 150.098 1.00 73.33  ?  291 PRO A C   1 
ATOM   2047  O O   . PRO A 1 302 ? 149.652 183.894 150.888 1.00 73.33  ?  291 PRO A O   1 
ATOM   2048  C CB  . PRO A 1 302 ? 151.991 182.859 149.636 1.00 73.33  ?  291 PRO A CB  1 
ATOM   2049  C CG  . PRO A 1 302 ? 152.319 184.264 149.293 1.00 73.33  ?  291 PRO A CG  1 
ATOM   2050  C CD  . PRO A 1 302 ? 151.606 184.588 148.007 1.00 73.33  ?  291 PRO A CD  1 
ATOM   2051  N N   . ILE A 1 303 ? 148.432 182.182 150.101 1.00 70.80  ?  292 ILE A N   1 
ATOM   2052  C CA  . ILE A 1 303 ? 147.294 182.517 150.944 1.00 70.80  ?  292 ILE A CA  1 
ATOM   2053  C C   . ILE A 1 303 ? 147.287 181.694 152.222 1.00 70.80  ?  292 ILE A C   1 
ATOM   2054  O O   . ILE A 1 303 ? 146.853 182.176 153.268 1.00 70.80  ?  292 ILE A O   1 
ATOM   2055  C CB  . ILE A 1 303 ? 145.980 182.360 150.155 1.00 70.80  ?  292 ILE A CB  1 
ATOM   2056  C CG1 . ILE A 1 303 ? 144.805 182.899 150.972 1.00 70.80  ?  292 ILE A CG1 1 
ATOM   2057  C CG2 . ILE A 1 303 ? 145.754 180.914 149.738 1.00 70.80  ?  292 ILE A CG2 1 
ATOM   2058  C CD1 . ILE A 1 303 ? 144.983 184.333 151.419 1.00 70.80  ?  292 ILE A CD1 1 
ATOM   2059  N N   . GLU A 1 304 ? 147.777 180.456 152.179 1.00 66.75  ?  293 GLU A N   1 
ATOM   2060  C CA  . GLU A 1 304 ? 147.902 179.695 153.413 1.00 66.75  ?  293 GLU A CA  1 
ATOM   2061  C C   . GLU A 1 304 ? 148.890 180.363 154.357 1.00 66.75  ?  293 GLU A C   1 
ATOM   2062  O O   . GLU A 1 304 ? 148.630 180.487 155.558 1.00 66.75  ?  293 GLU A O   1 
ATOM   2063  C CB  . GLU A 1 304 ? 148.320 178.257 153.110 1.00 66.75  ?  293 GLU A CB  1 
ATOM   2064  C CG  . GLU A 1 304 ? 147.241 177.445 152.422 1.00 66.75  ?  293 GLU A CG  1 
ATOM   2065  C CD  . GLU A 1 304 ? 147.605 175.982 152.284 1.00 66.75  ?  293 GLU A CD  1 
ATOM   2066  O OE1 . GLU A 1 304 ? 147.001 175.293 151.436 1.00 66.75  ?  293 GLU A OE1 1 
ATOM   2067  O OE2 . GLU A 1 304 ? 148.497 175.520 153.026 1.00 66.75  -1 293 GLU A OE2 1 
ATOM   2068  N N   . PHE A 1 305 ? 150.008 180.852 153.820 1.00 66.11  ?  294 PHE A N   1 
ATOM   2069  C CA  . PHE A 1 305 ? 150.993 181.550 154.639 1.00 66.11  ?  294 PHE A CA  1 
ATOM   2070  C C   . PHE A 1 305 ? 150.419 182.833 155.230 1.00 66.11  ?  294 PHE A C   1 
ATOM   2071  O O   . PHE A 1 305 ? 150.550 183.089 156.431 1.00 66.11  ?  294 PHE A O   1 
ATOM   2072  C CB  . PHE A 1 305 ? 152.241 181.847 153.812 1.00 66.11  ?  294 PHE A CB  1 
ATOM   2073  C CG  . PHE A 1 305 ? 153.243 182.705 154.523 1.00 66.11  ?  294 PHE A CG  1 
ATOM   2074  C CD1 . PHE A 1 305 ? 153.818 182.280 155.703 1.00 66.11  ?  294 PHE A CD1 1 
ATOM   2075  C CD2 . PHE A 1 305 ? 153.605 183.935 154.014 1.00 66.11  ?  294 PHE A CD2 1 
ATOM   2076  C CE1 . PHE A 1 305 ? 154.737 183.064 156.360 1.00 66.11  ?  294 PHE A CE1 1 
ATOM   2077  C CE2 . PHE A 1 305 ? 154.523 184.723 154.668 1.00 66.11  ?  294 PHE A CE2 1 
ATOM   2078  C CZ  . PHE A 1 305 ? 155.088 184.287 155.842 1.00 66.11  ?  294 PHE A CZ  1 
ATOM   2079  N N   . ILE A 1 306 ? 149.798 183.668 154.392 1.00 68.13  ?  295 ILE A N   1 
ATOM   2080  C CA  . ILE A 1 306 ? 149.260 184.944 154.868 1.00 68.13  ?  295 ILE A CA  1 
ATOM   2081  C C   . ILE A 1 306 ? 148.170 184.711 155.903 1.00 68.13  ?  295 ILE A C   1 
ATOM   2082  O O   . ILE A 1 306 ? 148.120 185.382 156.943 1.00 68.13  ?  295 ILE A O   1 
ATOM   2083  C CB  . ILE A 1 306 ? 148.740 185.779 153.684 1.00 68.13  ?  295 ILE A CB  1 
ATOM   2084  C CG1 . ILE A 1 306 ? 149.900 186.333 152.864 1.00 68.13  ?  295 ILE A CG1 1 
ATOM   2085  C CG2 . ILE A 1 306 ? 147.858 186.915 154.172 1.00 68.13  ?  295 ILE A CG2 1 
ATOM   2086  C CD1 . ILE A 1 306 ? 149.457 187.083 151.636 1.00 68.13  ?  295 ILE A CD1 1 
ATOM   2087  N N   . MET A 1 307 ? 147.281 183.754 155.638 1.00 68.19  ?  296 MET A N   1 
ATOM   2088  C CA  . MET A 1 307 ? 146.218 183.449 156.586 1.00 68.19  ?  296 MET A CA  1 
ATOM   2089  C C   . MET A 1 307 ? 146.783 182.920 157.896 1.00 68.19  ?  296 MET A C   1 
ATOM   2090  O O   . MET A 1 307 ? 146.276 183.252 158.969 1.00 68.19  ?  296 MET A O   1 
ATOM   2091  C CB  . MET A 1 307 ? 145.241 182.450 155.972 1.00 68.19  ?  296 MET A CB  1 
ATOM   2092  C CG  . MET A 1 307 ? 144.152 183.094 155.135 1.00 68.19  ?  296 MET A CG  1 
ATOM   2093  S SD  . MET A 1 307 ? 142.855 183.850 156.134 1.00 68.19  ?  296 MET A SD  1 
ATOM   2094  C CE  . MET A 1 307 ? 143.264 185.584 155.976 1.00 68.19  ?  296 MET A CE  1 
ATOM   2095  N N   . THR A 1 308 ? 147.850 182.121 157.833 1.00 65.21  ?  297 THR A N   1 
ATOM   2096  C CA  . THR A 1 308 ? 148.467 181.616 159.053 1.00 65.21  ?  297 THR A CA  1 
ATOM   2097  C C   . THR A 1 308 ? 149.121 182.725 159.864 1.00 65.21  ?  297 THR A C   1 
ATOM   2098  O O   . THR A 1 308 ? 148.981 182.753 161.091 1.00 65.21  ?  297 THR A O   1 
ATOM   2099  C CB  . THR A 1 308 ? 149.495 180.543 158.707 1.00 65.21  ?  297 THR A CB  1 
ATOM   2100  O OG1 . THR A 1 308 ? 148.977 179.707 157.667 1.00 65.21  ?  297 THR A OG1 1 
ATOM   2101  C CG2 . THR A 1 308 ? 149.805 179.702 159.910 1.00 65.21  ?  297 THR A CG2 1 
ATOM   2102  N N   . VAL A 1 309 ? 149.831 183.642 159.208 1.00 66.17  ?  298 VAL A N   1 
ATOM   2103  C CA  . VAL A 1 309 ? 150.440 184.754 159.934 1.00 66.17  ?  298 VAL A CA  1 
ATOM   2104  C C   . VAL A 1 309 ? 149.370 185.620 160.582 1.00 66.17  ?  298 VAL A C   1 
ATOM   2105  O O   . VAL A 1 309 ? 149.489 186.012 161.745 1.00 66.17  ?  298 VAL A O   1 
ATOM   2106  C CB  . VAL A 1 309 ? 151.352 185.580 159.010 1.00 66.17  ?  298 VAL A CB  1 
ATOM   2107  C CG1 . VAL A 1 309 ? 152.153 186.567 159.825 1.00 66.17  ?  298 VAL A CG1 1 
ATOM   2108  C CG2 . VAL A 1 309 ? 152.306 184.673 158.289 1.00 66.17  ?  298 VAL A CG2 1 
ATOM   2109  N N   . ILE A 1 310 ? 148.298 185.922 159.844 1.00 68.55  ?  299 ILE A N   1 
ATOM   2110  C CA  . ILE A 1 310 ? 147.251 186.773 160.402 1.00 68.55  ?  299 ILE A CA  1 
ATOM   2111  C C   . ILE A 1 310 ? 146.542 186.073 161.555 1.00 68.55  ?  299 ILE A C   1 
ATOM   2112  O O   . ILE A 1 310 ? 146.249 186.689 162.588 1.00 68.55  ?  299 ILE A O   1 
ATOM   2113  C CB  . ILE A 1 310 ? 146.265 187.200 159.299 1.00 68.55  ?  299 ILE A CB  1 
ATOM   2114  C CG1 . ILE A 1 310 ? 146.968 188.106 158.289 1.00 68.55  ?  299 ILE A CG1 1 
ATOM   2115  C CG2 . ILE A 1 310 ? 145.069 187.907 159.899 1.00 68.55  ?  299 ILE A CG2 1 
ATOM   2116  C CD1 . ILE A 1 310 ? 146.084 188.551 157.154 1.00 68.55  ?  299 ILE A CD1 1 
ATOM   2117  N N   . ALA A 1 311 ? 146.266 184.775 161.409 1.00 67.58  ?  300 ALA A N   1 
ATOM   2118  C CA  . ALA A 1 311 ? 145.620 184.021 162.474 1.00 67.58  ?  300 ALA A CA  1 
ATOM   2119  C C   . ALA A 1 311 ? 146.481 183.989 163.729 1.00 67.58  ?  300 ALA A C   1 
ATOM   2120  O O   . ALA A 1 311 ? 145.991 184.248 164.831 1.00 67.58  ?  300 ALA A O   1 
ATOM   2121  C CB  . ALA A 1 311 ? 145.314 182.603 161.997 1.00 67.58  ?  300 ALA A CB  1 
ATOM   2122  N N   . ALA A 1 312 ? 147.769 183.677 163.580 1.00 66.94  ?  301 ALA A N   1 
ATOM   2123  C CA  . ALA A 1 312 ? 148.654 183.636 164.737 1.00 66.94  ?  301 ALA A CA  1 
ATOM   2124  C C   . ALA A 1 312 ? 148.801 185.012 165.369 1.00 66.94  ?  301 ALA A C   1 
ATOM   2125  O O   . ALA A 1 312 ? 148.889 185.133 166.595 1.00 66.94  ?  301 ALA A O   1 
ATOM   2126  C CB  . ALA A 1 312 ? 150.016 183.076 164.334 1.00 66.94  ?  301 ALA A CB  1 
ATOM   2127  N N   . GLY A 1 313 ? 148.801 186.067 164.553 1.00 68.04  ?  302 GLY A N   1 
ATOM   2128  C CA  . GLY A 1 313 ? 148.937 187.407 165.099 1.00 68.04  ?  302 GLY A CA  1 
ATOM   2129  C C   . GLY A 1 313 ? 147.731 187.828 165.913 1.00 68.04  ?  302 GLY A C   1 
ATOM   2130  O O   . GLY A 1 313 ? 147.867 188.351 167.022 1.00 68.04  ?  302 GLY A O   1 
ATOM   2131  N N   . VAL A 1 314 ? 146.528 187.610 165.373 1.00 70.54  ?  303 VAL A N   1 
ATOM   2132  C CA  . VAL A 1 314 ? 145.322 187.962 166.121 1.00 70.54  ?  303 VAL A CA  1 
ATOM   2133  C C   . VAL A 1 314 ? 145.035 186.993 167.255 1.00 70.54  ?  303 VAL A C   1 
ATOM   2134  O O   . VAL A 1 314 ? 144.255 187.325 168.152 1.00 70.54  ?  303 VAL A O   1 
ATOM   2135  C CB  . VAL A 1 314 ? 144.082 188.058 165.210 1.00 70.54  ?  303 VAL A CB  1 
ATOM   2136  C CG1 . VAL A 1 314 ? 144.393 188.892 163.981 1.00 70.54  ?  303 VAL A CG1 1 
ATOM   2137  C CG2 . VAL A 1 314 ? 143.594 186.679 164.815 1.00 70.54  ?  303 VAL A CG2 1 
ATOM   2138  N N   . SER A 1 315 ? 145.645 185.809 167.247 1.00 69.83  ?  304 SER A N   1 
ATOM   2139  C CA  . SER A 1 315 ? 145.529 184.887 168.365 1.00 69.83  ?  304 SER A CA  1 
ATOM   2140  C C   . SER A 1 315 ? 146.514 185.186 169.482 1.00 69.83  ?  304 SER A C   1 
ATOM   2141  O O   . SER A 1 315 ? 146.215 184.902 170.646 1.00 69.83  ?  304 SER A O   1 
ATOM   2142  C CB  . SER A 1 315 ? 145.735 183.450 167.883 1.00 69.83  ?  304 SER A CB  1 
ATOM   2143  O OG  . SER A 1 315 ? 145.446 182.523 168.911 1.00 69.83  ?  304 SER A OG  1 
ATOM   2144  N N   . TYR A 1 316 ? 147.679 185.742 169.158 1.00 72.38  ?  305 TYR A N   1 
ATOM   2145  C CA  . TYR A 1 316 ? 148.659 186.104 170.175 1.00 72.38  ?  305 TYR A CA  1 
ATOM   2146  C C   . TYR A 1 316 ? 148.386 187.480 170.764 1.00 72.38  ?  305 TYR A C   1 
ATOM   2147  O O   . TYR A 1 316 ? 148.466 187.654 171.983 1.00 72.38  ?  305 TYR A O   1 
ATOM   2148  C CB  . TYR A 1 316 ? 150.069 186.059 169.583 1.00 72.38  ?  305 TYR A CB  1 
ATOM   2149  C CG  . TYR A 1 316 ? 151.153 186.504 170.538 1.00 72.38  ?  305 TYR A CG  1 
ATOM   2150  C CD1 . TYR A 1 316 ? 151.655 187.796 170.496 1.00 72.38  ?  305 TYR A CD1 1 
ATOM   2151  C CD2 . TYR A 1 316 ? 151.676 185.631 171.480 1.00 72.38  ?  305 TYR A CD2 1 
ATOM   2152  C CE1 . TYR A 1 316 ? 152.642 188.206 171.367 1.00 72.38  ?  305 TYR A CE1 1 
ATOM   2153  C CE2 . TYR A 1 316 ? 152.662 186.032 172.353 1.00 72.38  ?  305 TYR A CE2 1 
ATOM   2154  C CZ  . TYR A 1 316 ? 153.142 187.319 172.293 1.00 72.38  ?  305 TYR A CZ  1 
ATOM   2155  O OH  . TYR A 1 316 ? 154.128 187.721 173.164 1.00 72.38  ?  305 TYR A OH  1 
ATOM   2156  N N   . GLY A 1 317 ? 148.029 188.435 169.916 1.00 74.02  ?  306 GLY A N   1 
ATOM   2157  C CA  . GLY A 1 317 ? 147.724 189.771 170.390 1.00 74.02  ?  306 GLY A CA  1 
ATOM   2158  C C   . GLY A 1 317 ? 146.493 189.836 171.262 1.00 74.02  ?  306 GLY A C   1 
ATOM   2159  O O   . GLY A 1 317 ? 146.511 190.470 172.311 1.00 74.02  ?  306 GLY A O   1 
ATOM   2160  N N   . CYS A 1 318 ? 145.421 189.181 170.844 1.00 75.74  ?  307 CYS A N   1 
ATOM   2161  C CA  . CYS A 1 318 ? 144.174 189.244 171.596 1.00 75.74  ?  307 CYS A CA  1 
ATOM   2162  C C   . CYS A 1 318 ? 144.058 188.092 172.584 1.00 75.74  ?  307 CYS A C   1 
ATOM   2163  O O   . CYS A 1 318 ? 143.008 187.901 173.192 1.00 75.74  ?  307 CYS A O   1 
ATOM   2164  C CB  . CYS A 1 318 ? 142.986 189.252 170.641 1.00 75.74  ?  307 CYS A CB  1 
ATOM   2165  S SG  . CYS A 1 318 ? 143.137 190.407 169.262 1.00 75.74  ?  307 CYS A SG  1 
ATOM   2166  N N   . ASP A 1 319 ? 145.128 187.323 172.743 1.00 76.15  ?  308 ASP A N   1 
ATOM   2167  C CA  . ASP A 1 319 ? 145.132 186.210 173.689 1.00 76.15  ?  308 ASP A CA  1 
ATOM   2168  C C   . ASP A 1 319 ? 143.883 185.359 173.548 1.00 76.15  ?  308 ASP A C   1 
ATOM   2169  O O   . ASP A 1 319 ? 143.152 185.157 174.514 1.00 76.15  ?  308 ASP A O   1 
ATOM   2170  C CB  . ASP A 1 319 ? 145.272 186.723 175.122 1.00 76.15  ?  308 ASP A CB  1 
ATOM   2171  C CG  . ASP A 1 319 ? 145.493 185.606 176.124 1.00 76.15  ?  308 ASP A CG  1 
ATOM   2172  O OD1 . ASP A 1 319 ? 145.509 185.896 177.338 1.00 76.15  ?  308 ASP A OD1 1 
ATOM   2173  O OD2 . ASP A 1 319 ? 145.651 184.442 175.702 1.00 76.15  -1 308 ASP A OD2 1 
ATOM   2174  N N   . PHE A 1 320 ? 143.633 184.861 172.347 1.00 72.26  ?  309 PHE A N   1 
ATOM   2175  C CA  . PHE A 1 320 ? 142.452 184.048 172.102 1.00 72.26  ?  309 PHE A CA  1 
ATOM   2176  C C   . PHE A 1 320 ? 142.466 182.790 172.943 1.00 72.26  ?  309 PHE A C   1 
ATOM   2177  O O   . PHE A 1 320 ? 141.418 182.234 173.250 1.00 72.26  ?  309 PHE A O   1 
ATOM   2178  C CB  . PHE A 1 320 ? 142.375 183.670 170.628 1.00 72.26  ?  309 PHE A CB  1 
ATOM   2179  C CG  . PHE A 1 320 ? 141.825 184.749 169.748 1.00 72.26  ?  309 PHE A CG  1 
ATOM   2180  C CD1 . PHE A 1 320 ? 141.561 186.009 170.250 1.00 72.26  ?  309 PHE A CD1 1 
ATOM   2181  C CD2 . PHE A 1 320 ? 141.572 184.497 168.412 1.00 72.26  ?  309 PHE A CD2 1 
ATOM   2182  C CE1 . PHE A 1 320 ? 141.050 186.998 169.434 1.00 72.26  ?  309 PHE A CE1 1 
ATOM   2183  C CE2 . PHE A 1 320 ? 141.065 185.481 167.591 1.00 72.26  ?  309 PHE A CE2 1 
ATOM   2184  C CZ  . PHE A 1 320 ? 140.804 186.735 168.102 1.00 72.26  ?  309 PHE A CZ  1 
ATOM   2185  N N   . LYS A 1 321 ? 143.651 182.329 173.314 1.00 72.97  ?  310 LYS A N   1 
ATOM   2186  C CA  . LYS A 1 321 ? 143.760 181.096 174.080 1.00 72.97  ?  310 LYS A CA  1 
ATOM   2187  C C   . LYS A 1 321 ? 143.082 181.220 175.425 1.00 72.97  ?  310 LYS A C   1 
ATOM   2188  O O   . LYS A 1 321 ? 142.461 180.274 175.902 1.00 72.97  ?  310 LYS A O   1 
ATOM   2189  C CB  . LYS A 1 321 ? 145.220 180.723 174.294 1.00 72.97  ?  310 LYS A CB  1 
ATOM   2190  C CG  . LYS A 1 321 ? 145.419 179.376 174.963 1.00 72.97  ?  310 LYS A CG  1 
ATOM   2191  C CD  . LYS A 1 321 ? 146.789 179.298 175.607 1.00 72.97  ?  310 LYS A CD  1 
ATOM   2192  C CE  . LYS A 1 321 ? 147.868 179.780 174.652 1.00 72.97  ?  310 LYS A CE  1 
ATOM   2193  N NZ  . LYS A 1 321 ? 149.197 179.846 175.316 1.00 72.97  1  310 LYS A NZ  1 
ATOM   2194  N N   . ASN A 1 322 ? 143.204 182.381 176.048 1.00 75.65  ?  311 ASN A N   1 
ATOM   2195  C CA  . ASN A 1 322 ? 142.611 182.580 177.356 1.00 75.65  ?  311 ASN A CA  1 
ATOM   2196  C C   . ASN A 1 322 ? 141.254 183.230 177.219 1.00 75.65  ?  311 ASN A C   1 
ATOM   2197  O O   . ASN A 1 322 ? 140.323 182.885 177.940 1.00 75.65  ?  311 ASN A O   1 
ATOM   2198  C CB  . ASN A 1 322 ? 143.532 183.438 178.219 1.00 75.65  ?  311 ASN A CB  1 
ATOM   2199  C CG  . ASN A 1 322 ? 144.907 182.823 178.385 1.00 75.65  ?  311 ASN A CG  1 
ATOM   2200  O OD1 . ASN A 1 322 ? 145.876 183.514 178.690 1.00 75.65  ?  311 ASN A OD1 1 
ATOM   2201  N ND2 . ASN A 1 322 ? 145.000 181.516 178.175 1.00 75.65  ?  311 ASN A ND2 1 
ATOM   2202  N N   . ARG A 1 323 ? 141.131 184.163 176.290 1.00 76.59  ?  312 ARG A N   1 
ATOM   2203  C CA  . ARG A 1 323 ? 139.869 184.857 176.093 1.00 76.59  ?  312 ARG A CA  1 
ATOM   2204  C C   . ARG A 1 323 ? 138.756 183.953 175.571 1.00 76.59  ?  312 ARG A C   1 
ATOM   2205  O O   . ARG A 1 323 ? 137.618 184.054 176.019 1.00 76.59  ?  312 ARG A O   1 
ATOM   2206  C CB  . ARG A 1 323 ? 140.068 186.024 175.128 1.00 76.59  ?  312 ARG A CB  1 
ATOM   2207  C CG  . ARG A 1 323 ? 138.830 186.874 174.915 1.00 76.59  ?  312 ARG A CG  1 
ATOM   2208  C CD  . ARG A 1 323 ? 139.125 188.021 173.967 1.00 76.59  ?  312 ARG A CD  1 
ATOM   2209  N NE  . ARG A 1 323 ? 140.298 188.777 174.388 1.00 76.59  ?  312 ARG A NE  1 
ATOM   2210  C CZ  . ARG A 1 323 ? 140.779 189.828 173.736 1.00 76.59  ?  312 ARG A CZ  1 
ATOM   2211  N NH1 . ARG A 1 323 ? 141.853 190.458 174.192 1.00 76.59  1  312 ARG A NH1 1 
ATOM   2212  N NH2 . ARG A 1 323 ? 140.186 190.249 172.627 1.00 76.59  ?  312 ARG A NH2 1 
ATOM   2213  N N   . PHE A 1 324 ? 139.067 183.082 174.620 1.00 73.59  ?  313 PHE A N   1 
ATOM   2214  C CA  . PHE A 1 324 ? 138.036 182.240 174.025 1.00 73.59  ?  313 PHE A CA  1 
ATOM   2215  C C   . PHE A 1 324 ? 138.300 180.759 174.225 1.00 73.59  ?  313 PHE A C   1 
ATOM   2216  O O   . PHE A 1 324 ? 137.627 179.930 173.626 1.00 73.59  ?  313 PHE A O   1 
ATOM   2217  C CB  . PHE A 1 324 ? 137.913 182.534 172.535 1.00 73.59  ?  313 PHE A CB  1 
ATOM   2218  C CG  . PHE A 1 324 ? 137.664 183.976 172.220 1.00 73.59  ?  313 PHE A CG  1 
ATOM   2219  C CD1 . PHE A 1 324 ? 136.596 184.646 172.785 1.00 73.59  ?  313 PHE A CD1 1 
ATOM   2220  C CD2 . PHE A 1 324 ? 138.489 184.656 171.344 1.00 73.59  ?  313 PHE A CD2 1 
ATOM   2221  C CE1 . PHE A 1 324 ? 136.360 185.973 172.491 1.00 73.59  ?  313 PHE A CE1 1 
ATOM   2222  C CE2 . PHE A 1 324 ? 138.259 185.982 171.044 1.00 73.59  ?  313 PHE A CE2 1 
ATOM   2223  C CZ  . PHE A 1 324 ? 137.192 186.642 171.618 1.00 73.59  ?  313 PHE A CZ  1 
ATOM   2224  N N   . LYS A 1 325 ? 139.278 180.422 175.052 1.00 71.22  ?  314 LYS A N   1 
ATOM   2225  C CA  . LYS A 1 325 ? 139.571 179.022 175.346 1.00 71.22  ?  314 LYS A CA  1 
ATOM   2226  C C   . LYS A 1 325 ? 139.739 178.208 174.077 1.00 71.22  ?  314 LYS A C   1 
ATOM   2227  O O   . LYS A 1 325 ? 139.110 177.168 173.915 1.00 71.22  ?  314 LYS A O   1 
ATOM   2228  C CB  . LYS A 1 325 ? 138.462 178.428 176.208 1.00 71.22  ?  314 LYS A CB  1 
ATOM   2229  C CG  . LYS A 1 325 ? 138.070 179.301 177.385 1.00 71.22  ?  314 LYS A CG  1 
ATOM   2230  C CD  . LYS A 1 325 ? 139.273 179.627 178.253 1.00 71.22  ?  314 LYS A CD  1 
ATOM   2231  C CE  . LYS A 1 325 ? 138.882 180.534 179.405 1.00 71.22  ?  314 LYS A CE  1 
ATOM   2232  N NZ  . LYS A 1 325 ? 137.815 179.923 180.244 1.00 71.22  1  314 LYS A NZ  1 
ATOM   2233  N N   . VAL A 1 326 ? 140.596 178.669 173.182 1.00 67.03  ?  315 VAL A N   1 
ATOM   2234  C CA  . VAL A 1 326 ? 140.795 177.983 171.915 1.00 67.03  ?  315 VAL A CA  1 
ATOM   2235  C C   . VAL A 1 326 ? 142.006 177.061 172.011 1.00 67.03  ?  315 VAL A C   1 
ATOM   2236  O O   . VAL A 1 326 ? 142.918 177.263 172.814 1.00 67.03  ?  315 VAL A O   1 
ATOM   2237  C CB  . VAL A 1 326 ? 140.948 178.988 170.762 1.00 67.03  ?  315 VAL A CB  1 
ATOM   2238  C CG1 . VAL A 1 326 ? 139.792 179.955 170.759 1.00 67.03  ?  315 VAL A CG1 1 
ATOM   2239  C CG2 . VAL A 1 326 ? 142.260 179.734 170.875 1.00 67.03  ?  315 VAL A CG2 1 
ATOM   2240  N N   . ALA A 1 327 ? 142.004 176.024 171.178 1.00 63.76  ?  316 ALA A N   1 
ATOM   2241  C CA  . ALA A 1 327 ? 143.095 175.061 171.136 1.00 63.76  ?  316 ALA A CA  1 
ATOM   2242  C C   . ALA A 1 327 ? 144.150 175.554 170.157 1.00 63.76  ?  316 ALA A C   1 
ATOM   2243  O O   . ALA A 1 327 ? 143.840 175.840 168.998 1.00 63.76  ?  316 ALA A O   1 
ATOM   2244  C CB  . ALA A 1 327 ? 142.588 173.680 170.732 1.00 63.76  ?  316 ALA A CB  1 
ATOM   2245  N N   . VAL A 1 328 ? 145.390 175.653 170.625 1.00 62.41  ?  317 VAL A N   1 
ATOM   2246  C CA  . VAL A 1 328 ? 146.486 176.183 169.832 1.00 62.41  ?  317 VAL A CA  1 
ATOM   2247  C C   . VAL A 1 328 ? 147.499 175.076 169.584 1.00 62.41  ?  317 VAL A C   1 
ATOM   2248  O O   . VAL A 1 328 ? 147.439 173.995 170.175 1.00 62.41  ?  317 VAL A O   1 
ATOM   2249  C CB  . VAL A 1 328 ? 147.151 177.392 170.517 1.00 62.41  ?  317 VAL A CB  1 
ATOM   2250  C CG1 . VAL A 1 328 ? 146.147 178.506 170.705 1.00 62.41  ?  317 VAL A CG1 1 
ATOM   2251  C CG2 . VAL A 1 328 ? 147.740 176.981 171.845 1.00 62.41  ?  317 VAL A CG2 1 
ATOM   2252  N N   . VAL A 1 329 ? 148.443 175.354 168.682 1.00 61.46  ?  318 VAL A N   1 
ATOM   2253  C CA  . VAL A 1 329 ? 149.466 174.370 168.341 1.00 61.46  ?  318 VAL A CA  1 
ATOM   2254  C C   . VAL A 1 329 ? 150.360 174.091 169.542 1.00 61.46  ?  318 VAL A C   1 
ATOM   2255  O O   . VAL A 1 329 ? 150.802 172.956 169.758 1.00 61.46  ?  318 VAL A O   1 
ATOM   2256  C CB  . VAL A 1 329 ? 150.274 174.847 167.117 1.00 61.46  ?  318 VAL A CB  1 
ATOM   2257  C CG1 . VAL A 1 329 ? 151.605 174.134 167.031 1.00 61.46  ?  318 VAL A CG1 1 
ATOM   2258  C CG2 . VAL A 1 329 ? 149.481 174.623 165.844 1.00 61.46  ?  318 VAL A CG2 1 
ATOM   2259  N N   . GLY A 1 330 ? 150.622 175.108 170.349 1.00 64.54  ?  319 GLY A N   1 
ATOM   2260  C CA  . GLY A 1 330 ? 151.366 174.918 171.573 1.00 64.54  ?  319 GLY A CA  1 
ATOM   2261  C C   . GLY A 1 330 ? 152.858 175.054 171.380 1.00 64.54  ?  319 GLY A C   1 
ATOM   2262  O O   . GLY A 1 330 ? 153.361 175.426 170.317 1.00 64.54  ?  319 GLY A O   1 
ATOM   2263  N N   . ASP A 1 331 ? 153.582 174.740 172.447 1.00 67.61  ?  320 ASP A N   1 
ATOM   2264  C CA  . ASP A 1 331 ? 155.034 174.835 172.433 1.00 67.61  ?  320 ASP A CA  1 
ATOM   2265  C C   . ASP A 1 331 ? 155.623 173.538 171.897 1.00 67.61  ?  320 ASP A C   1 
ATOM   2266  O O   . ASP A 1 331 ? 155.290 172.451 172.380 1.00 67.61  ?  320 ASP A O   1 
ATOM   2267  C CB  . ASP A 1 331 ? 155.561 175.135 173.831 1.00 67.61  ?  320 ASP A CB  1 
ATOM   2268  C CG  . ASP A 1 331 ? 155.599 176.617 174.126 1.00 67.61  ?  320 ASP A CG  1 
ATOM   2269  O OD1 . ASP A 1 331 ? 154.901 177.056 175.064 1.00 67.61  ?  320 ASP A OD1 1 
ATOM   2270  O OD2 . ASP A 1 331 ? 156.323 177.347 173.416 1.00 67.61  -1 320 ASP A OD2 1 
ATOM   2271  N N   . MET A 1 332 ? 156.489 173.652 170.897 1.00 65.10  ?  321 MET A N   1 
ATOM   2272  C CA  . MET A 1 332 ? 157.122 172.502 170.272 1.00 65.10  ?  321 MET A CA  1 
ATOM   2273  C C   . MET A 1 332 ? 158.563 172.377 170.746 1.00 65.10  ?  321 MET A C   1 
ATOM   2274  O O   . MET A 1 332 ? 159.234 173.381 170.994 1.00 65.10  ?  321 MET A O   1 
ATOM   2275  C CB  . MET A 1 332 ? 157.078 172.623 168.748 1.00 65.10  ?  321 MET A CB  1 
ATOM   2276  C CG  . MET A 1 332 ? 155.708 172.356 168.152 1.00 65.10  ?  321 MET A CG  1 
ATOM   2277  S SD  . MET A 1 332 ? 155.184 173.615 166.979 1.00 65.10  ?  321 MET A SD  1 
ATOM   2278  C CE  . MET A 1 332 ? 156.395 173.390 165.687 1.00 65.10  ?  321 MET A CE  1 
ATOM   2279  N N   . ASN A 1 333 ? 159.024 171.137 170.880 1.00 65.26  ?  322 ASN A N   1 
ATOM   2280  C CA  . ASN A 1 333 ? 160.394 170.873 171.305 1.00 65.26  ?  322 ASN A CA  1 
ATOM   2281  C C   . ASN A 1 333 ? 161.365 171.291 170.209 1.00 65.26  ?  322 ASN A C   1 
ATOM   2282  O O   . ASN A 1 333 ? 161.343 170.713 169.118 1.00 65.26  ?  322 ASN A O   1 
ATOM   2283  C CB  . ASN A 1 333 ? 160.575 169.393 171.626 1.00 65.26  ?  322 ASN A CB  1 
ATOM   2284  C CG  . ASN A 1 333 ? 162.028 169.008 171.832 1.00 65.26  ?  322 ASN A CG  1 
ATOM   2285  O OD1 . ASN A 1 333 ? 162.749 169.649 172.598 1.00 65.26  ?  322 ASN A OD1 1 
ATOM   2286  N ND2 . ASN A 1 333 ? 162.464 167.957 171.151 1.00 65.26  ?  322 ASN A ND2 1 
ATOM   2287  N N   . PRO A 1 334 ? 162.224 172.275 170.453 1.00 62.58  ?  323 PRO A N   1 
ATOM   2288  C CA  . PRO A 1 334 ? 163.133 172.730 169.399 1.00 62.58  ?  323 PRO A CA  1 
ATOM   2289  C C   . PRO A 1 334 ? 164.236 171.722 169.134 1.00 62.58  ?  323 PRO A C   1 
ATOM   2290  O O   . PRO A 1 334 ? 165.146 171.527 169.941 1.00 62.58  ?  323 PRO A O   1 
ATOM   2291  C CB  . PRO A 1 334 ? 163.701 174.036 169.963 1.00 62.58  ?  323 PRO A CB  1 
ATOM   2292  C CG  . PRO A 1 334 ? 163.610 173.872 171.435 1.00 62.58  ?  323 PRO A CG  1 
ATOM   2293  C CD  . PRO A 1 334 ? 162.388 173.041 171.700 1.00 62.58  ?  323 PRO A CD  1 
ATOM   2294  N N   . GLY A 1 335 ? 164.151 171.084 167.975 1.00 56.35  ?  324 GLY A N   1 
ATOM   2295  C CA  . GLY A 1 335 ? 165.137 170.109 167.563 1.00 56.35  ?  324 GLY A CA  1 
ATOM   2296  C C   . GLY A 1 335 ? 164.515 168.778 167.186 1.00 56.35  ?  324 GLY A C   1 
ATOM   2297  O O   . GLY A 1 335 ? 163.305 168.565 167.270 1.00 56.35  ?  324 GLY A O   1 
ATOM   2298  N N   . PHE A 1 336 ? 165.380 167.869 166.759 1.00 54.38  ?  325 PHE A N   1 
ATOM   2299  C CA  . PHE A 1 336 ? 164.963 166.550 166.314 1.00 54.38  ?  325 PHE A CA  1 
ATOM   2300  C C   . PHE A 1 336 ? 165.012 165.555 167.465 1.00 54.38  ?  325 PHE A C   1 
ATOM   2301  O O   . PHE A 1 336 ? 165.570 165.820 168.531 1.00 54.38  ?  325 PHE A O   1 
ATOM   2302  C CB  . PHE A 1 336 ? 165.847 166.065 165.165 1.00 54.38  ?  325 PHE A CB  1 
ATOM   2303  C CG  . PHE A 1 336 ? 165.735 166.897 163.926 1.00 54.38  ?  325 PHE A CG  1 
ATOM   2304  C CD1 . PHE A 1 336 ? 164.821 166.575 162.944 1.00 54.38  ?  325 PHE A CD1 1 
ATOM   2305  C CD2 . PHE A 1 336 ? 166.534 168.008 163.748 1.00 54.38  ?  325 PHE A CD2 1 
ATOM   2306  C CE1 . PHE A 1 336 ? 164.710 167.343 161.809 1.00 54.38  ?  325 PHE A CE1 1 
ATOM   2307  C CE2 . PHE A 1 336 ? 166.428 168.778 162.612 1.00 54.38  ?  325 PHE A CE2 1 
ATOM   2308  C CZ  . PHE A 1 336 ? 165.514 168.444 161.643 1.00 54.38  ?  325 PHE A CZ  1 
ATOM   2309  N N   . GLN A 1 337 ? 164.415 164.426 167.245 1.00 58.17  ?  326 GLN A N   1 
ATOM   2310  C CA  . GLN A 1 337 ? 164.440 163.378 168.247 1.00 58.17  ?  326 GLN A CA  1 
ATOM   2311  C C   . GLN A 1 337 ? 165.525 162.358 167.920 1.00 58.17  ?  326 GLN A C   1 
ATOM   2312  O O   . GLN A 1 337 ? 165.876 162.172 166.750 1.00 58.17  ?  326 GLN A O   1 
ATOM   2313  C CB  . GLN A 1 337 ? 163.089 162.675 168.318 1.00 58.17  ?  326 GLN A CB  1 
ATOM   2314  C CG  . GLN A 1 337 ? 161.923 163.584 168.648 1.00 58.17  ?  326 GLN A CG  1 
ATOM   2315  C CD  . GLN A 1 337 ? 161.912 164.021 170.095 1.00 58.17  ?  326 GLN A CD  1 
ATOM   2316  O OE1 . GLN A 1 337 ? 161.621 165.176 170.404 1.00 58.17  ?  326 GLN A OE1 1 
ATOM   2317  N NE2 . GLN A 1 337 ? 162.230 163.100 170.993 1.00 58.17  ?  326 GLN A NE2 1 
ATOM   2318  N N   . PRO A 1 338 ? 166.083 161.696 168.927 1.00 60.60  ?  327 PRO A N   1 
ATOM   2319  C CA  . PRO A 1 338 ? 167.040 160.621 168.672 1.00 60.60  ?  327 PRO A CA  1 
ATOM   2320  C C   . PRO A 1 338 ? 166.397 159.501 167.876 1.00 60.60  ?  327 PRO A C   1 
ATOM   2321  O O   . PRO A 1 338 ? 165.163 159.375 167.850 1.00 60.60  ?  327 PRO A O   1 
ATOM   2322  C CB  . PRO A 1 338 ? 167.426 160.151 170.082 1.00 60.60  ?  327 PRO A CB  1 
ATOM   2323  C CG  . PRO A 1 338 ? 167.156 161.320 170.950 1.00 60.60  ?  327 PRO A CG  1 
ATOM   2324  C CD  . PRO A 1 338 ? 165.960 161.996 170.364 1.00 60.60  ?  327 PRO A CD  1 
ATOM   2325  N N   . PRO A 1 339 ? 167.194 158.673 167.202 1.00 58.56  ?  328 PRO A N   1 
ATOM   2326  C CA  . PRO A 1 339 ? 166.621 157.556 166.446 1.00 58.56  ?  328 PRO A CA  1 
ATOM   2327  C C   . PRO A 1 339 ? 165.897 156.582 167.360 1.00 58.56  ?  328 PRO A C   1 
ATOM   2328  O O   . PRO A 1 339 ? 166.258 156.397 168.524 1.00 58.56  ?  328 PRO A O   1 
ATOM   2329  C CB  . PRO A 1 339 ? 167.842 156.906 165.791 1.00 58.56  ?  328 PRO A CB  1 
ATOM   2330  C CG  . PRO A 1 339 ? 168.881 157.966 165.785 1.00 58.56  ?  328 PRO A CG  1 
ATOM   2331  C CD  . PRO A 1 339 ? 168.648 158.781 167.013 1.00 58.56  ?  328 PRO A CD  1 
ATOM   2332  N N   . ILE A 1 340 ? 164.858 155.956 166.817 1.00 59.38  ?  329 ILE A N   1 
ATOM   2333  C CA  . ILE A 1 340 ? 164.021 155.021 167.554 1.00 59.38  ?  329 ILE A CA  1 
ATOM   2334  C C   . ILE A 1 340 ? 164.176 153.644 166.928 1.00 59.38  ?  329 ILE A C   1 
ATOM   2335  O O   . ILE A 1 340 ? 164.553 153.521 165.758 1.00 59.38  ?  329 ILE A O   1 
ATOM   2336  C CB  . ILE A 1 340 ? 162.543 155.464 167.553 1.00 59.38  ?  329 ILE A CB  1 
ATOM   2337  C CG1 . ILE A 1 340 ? 161.822 154.938 168.793 1.00 59.38  ?  329 ILE A CG1 1 
ATOM   2338  C CG2 . ILE A 1 340 ? 161.832 154.994 166.293 1.00 59.38  ?  329 ILE A CG2 1 
ATOM   2339  C CD1 . ILE A 1 340 ? 160.336 155.203 168.788 1.00 59.38  ?  329 ILE A CD1 1 
ATOM   2340  N N   . THR A 1 341 ? 163.906 152.612 167.715 1.00 62.79  ?  330 THR A N   1 
ATOM   2341  C CA  . THR A 1 341 ? 163.945 151.247 167.206 1.00 62.79  ?  330 THR A CA  1 
ATOM   2342  C C   . THR A 1 341 ? 162.526 150.757 166.946 1.00 62.79  ?  330 THR A C   1 
ATOM   2343  O O   . THR A 1 341 ? 161.675 150.853 167.836 1.00 62.79  ?  330 THR A O   1 
ATOM   2344  C CB  . THR A 1 341 ? 164.639 150.320 168.192 1.00 62.79  ?  330 THR A CB  1 
ATOM   2345  O OG1 . THR A 1 341 ? 165.760 150.995 168.772 1.00 62.79  ?  330 THR A OG1 1 
ATOM   2346  C CG2 . THR A 1 341 ? 165.131 149.072 167.482 1.00 62.79  ?  330 THR A CG2 1 
ATOM   2347  N N   . PRO A 1 342 ? 162.235 150.237 165.756 1.00 63.18  ?  331 PRO A N   1 
ATOM   2348  C CA  . PRO A 1 342 ? 160.860 149.833 165.449 1.00 63.18  ?  331 PRO A CA  1 
ATOM   2349  C C   . PRO A 1 342 ? 160.410 148.675 166.325 1.00 63.18  ?  331 PRO A C   1 
ATOM   2350  O O   . PRO A 1 342 ? 161.112 147.675 166.478 1.00 63.18  ?  331 PRO A O   1 
ATOM   2351  C CB  . PRO A 1 342 ? 160.930 149.422 163.974 1.00 63.18  ?  331 PRO A CB  1 
ATOM   2352  C CG  . PRO A 1 342 ? 162.198 150.005 163.459 1.00 63.18  ?  331 PRO A CG  1 
ATOM   2353  C CD  . PRO A 1 342 ? 163.137 150.042 164.612 1.00 63.18  ?  331 PRO A CD  1 
ATOM   2354  N N   . ASP A 1 343 ? 159.221 148.820 166.902 1.00 63.52  ?  332 ASP A N   1 
ATOM   2355  C CA  . ASP A 1 343 ? 158.618 147.758 167.695 1.00 63.52  ?  332 ASP A CA  1 
ATOM   2356  C C   . ASP A 1 343 ? 158.168 146.651 166.754 1.00 63.52  ?  332 ASP A C   1 
ATOM   2357  O O   . ASP A 1 343 ? 157.413 146.901 165.810 1.00 63.52  ?  332 ASP A O   1 
ATOM   2358  C CB  . ASP A 1 343 ? 157.444 148.293 168.507 1.00 63.52  ?  332 ASP A CB  1 
ATOM   2359  C CG  . ASP A 1 343 ? 157.885 149.135 169.681 1.00 63.52  ?  332 ASP A CG  1 
ATOM   2360  O OD1 . ASP A 1 343 ? 158.973 148.870 170.230 1.00 63.52  ?  332 ASP A OD1 1 
ATOM   2361  O OD2 . ASP A 1 343 ? 157.144 150.068 170.053 1.00 63.52  -1 332 ASP A OD2 1 
ATOM   2362  N N   . VAL A 1 344 ? 158.673 145.450 166.997 1.00 62.77  ?  333 VAL A N   1 
ATOM   2363  C CA  . VAL A 1 344 ? 158.274 144.321 166.188 1.00 62.77  ?  333 VAL A CA  1 
ATOM   2364  C C   . VAL A 1 344 ? 156.850 143.970 166.563 1.00 62.77  ?  333 VAL A C   1 
ATOM   2365  O O   . VAL A 1 344 ? 156.124 143.393 165.765 1.00 62.77  ?  333 VAL A O   1 
ATOM   2366  C CB  . VAL A 1 344 ? 159.212 143.122 166.402 1.00 62.77  ?  333 VAL A CB  1 
ATOM   2367  C CG1 . VAL A 1 344 ? 160.622 143.471 165.954 1.00 62.77  ?  333 VAL A CG1 1 
ATOM   2368  C CG2 . VAL A 1 344 ? 159.206 142.695 167.861 1.00 62.77  ?  333 VAL A CG2 1 
ATOM   2369  N N   . GLU A 1 345 ? 156.436 144.331 167.773 1.00 64.89  ?  334 GLU A N   1 
ATOM   2370  C CA  . GLU A 1 345 ? 155.056 144.096 168.159 1.00 64.89  ?  334 GLU A CA  1 
ATOM   2371  C C   . GLU A 1 345 ? 154.144 144.957 167.305 1.00 64.89  ?  334 GLU A C   1 
ATOM   2372  O O   . GLU A 1 345 ? 153.139 144.477 166.790 1.00 64.89  ?  334 GLU A O   1 
ATOM   2373  C CB  . GLU A 1 345 ? 154.827 144.382 169.644 1.00 64.89  ?  334 GLU A CB  1 
ATOM   2374  C CG  . GLU A 1 345 ? 153.384 144.177 170.077 1.00 64.89  ?  334 GLU A CG  1 
ATOM   2375  C CD  . GLU A 1 345 ? 153.144 144.536 171.530 1.00 64.89  ?  334 GLU A CD  1 
ATOM   2376  O OE1 . GLU A 1 345 ? 151.996 144.387 171.997 1.00 64.89  ?  334 GLU A OE1 1 
ATOM   2377  O OE2 . GLU A 1 345 ? 154.101 144.966 172.206 1.00 64.89  -1 334 GLU A OE2 1 
ATOM   2378  N N   . THR A 1 346 ? 154.494 146.227 167.146 1.00 60.32  ?  335 THR A N   1 
ATOM   2379  C CA  . THR A 1 346 ? 153.709 147.104 166.296 1.00 60.32  ?  335 THR A CA  1 
ATOM   2380  C C   . THR A 1 346 ? 153.754 146.580 164.873 1.00 60.32  ?  335 THR A C   1 
ATOM   2381  O O   . THR A 1 346 ? 152.744 146.586 164.179 1.00 60.32  ?  335 THR A O   1 
ATOM   2382  C CB  . THR A 1 346 ? 154.213 148.553 166.348 1.00 60.32  ?  335 THR A CB  1 
ATOM   2383  O OG1 . THR A 1 346 ? 154.164 149.029 167.698 1.00 60.32  ?  335 THR A OG1 1 
ATOM   2384  C CG2 . THR A 1 346 ? 153.351 149.450 165.470 1.00 60.32  ?  335 THR A CG2 1 
ATOM   2385  N N   . PHE A 1 347 ? 154.915 146.099 164.446 1.00 58.40  ?  336 PHE A N   1 
ATOM   2386  C CA  . PHE A 1 347 ? 155.031 145.527 163.114 1.00 58.40  ?  336 PHE A CA  1 
ATOM   2387  C C   . PHE A 1 347 ? 154.059 144.375 162.949 1.00 58.40  ?  336 PHE A C   1 
ATOM   2388  O O   . PHE A 1 347 ? 153.352 144.298 161.951 1.00 58.40  ?  336 PHE A O   1 
ATOM   2389  C CB  . PHE A 1 347 ? 156.455 145.042 162.855 1.00 58.40  ?  336 PHE A CB  1 
ATOM   2390  C CG  . PHE A 1 347 ? 157.395 146.117 162.406 1.00 58.40  ?  336 PHE A CG  1 
ATOM   2391  C CD1 . PHE A 1 347 ? 157.258 147.415 162.860 1.00 58.40  ?  336 PHE A CD1 1 
ATOM   2392  C CD2 . PHE A 1 347 ? 158.428 145.825 161.534 1.00 58.40  ?  336 PHE A CD2 1 
ATOM   2393  C CE1 . PHE A 1 347 ? 158.127 148.402 162.448 1.00 58.40  ?  336 PHE A CE1 1 
ATOM   2394  C CE2 . PHE A 1 347 ? 159.302 146.808 161.117 1.00 58.40  ?  336 PHE A CE2 1 
ATOM   2395  C CZ  . PHE A 1 347 ? 159.149 148.100 161.573 1.00 58.40  ?  336 PHE A CZ  1 
ATOM   2396  N N   . GLN A 1 348 ? 154.006 143.488 163.934 1.00 62.44  ?  337 GLN A N   1 
ATOM   2397  C CA  . GLN A 1 348 ? 153.108 142.344 163.877 1.00 62.44  ?  337 GLN A CA  1 
ATOM   2398  C C   . GLN A 1 348 ? 151.655 142.764 163.852 1.00 62.44  ?  337 GLN A C   1 
ATOM   2399  O O   . GLN A 1 348 ? 150.841 142.139 163.178 1.00 62.44  ?  337 GLN A O   1 
ATOM   2400  C CB  . GLN A 1 348 ? 153.342 141.436 165.080 1.00 62.44  ?  337 GLN A CB  1 
ATOM   2401  C CG  . GLN A 1 348 ? 154.734 140.835 165.146 1.00 62.44  ?  337 GLN A CG  1 
ATOM   2402  C CD  . GLN A 1 348 ? 155.070 140.298 166.524 1.00 62.44  ?  337 GLN A CD  1 
ATOM   2403  O OE1 . GLN A 1 348 ? 156.177 139.818 166.762 1.00 62.44  ?  337 GLN A OE1 1 
ATOM   2404  N NE2 . GLN A 1 348 ? 154.113 140.383 167.440 1.00 62.44  ?  337 GLN A NE2 1 
ATOM   2405  N N   . ASN A 1 349 ? 151.317 143.814 164.587 1.00 61.96  ?  338 ASN A N   1 
ATOM   2406  C CA  . ASN A 1 349 ? 149.921 144.228 164.674 1.00 61.96  ?  338 ASN A CA  1 
ATOM   2407  C C   . ASN A 1 349 ? 149.473 145.147 163.542 1.00 61.96  ?  338 ASN A C   1 
ATOM   2408  O O   . ASN A 1 349 ? 148.291 145.460 163.444 1.00 61.96  ?  338 ASN A O   1 
ATOM   2409  C CB  . ASN A 1 349 ? 149.664 144.915 166.014 1.00 61.96  ?  338 ASN A CB  1 
ATOM   2410  C CG  . ASN A 1 349 ? 150.031 144.044 167.199 1.00 61.96  ?  338 ASN A CG  1 
ATOM   2411  O OD1 . ASN A 1 349 ? 150.496 142.917 167.038 1.00 61.96  ?  338 ASN A OD1 1 
ATOM   2412  N ND2 . ASN A 1 349 ? 149.826 144.566 168.402 1.00 61.96  ?  338 ASN A ND2 1 
ATOM   2413  N N   . THR A 1 350 ? 150.395 145.582 162.690 1.00 57.58  ?  339 THR A N   1 
ATOM   2414  C CA  . THR A 1 350 ? 150.039 146.540 161.642 1.00 57.58  ?  339 THR A CA  1 
ATOM   2415  C C   . THR A 1 350 ? 150.493 146.148 160.241 1.00 57.58  ?  339 THR A C   1 
ATOM   2416  O O   . THR A 1 350 ? 150.572 146.998 159.363 1.00 57.58  ?  339 THR A O   1 
ATOM   2417  C CB  . THR A 1 350 ? 150.613 147.934 161.961 1.00 57.58  ?  339 THR A CB  1 
ATOM   2418  O OG1 . THR A 1 350 ? 152.042 147.856 162.039 1.00 57.58  ?  339 THR A OG1 1 
ATOM   2419  C CG2 . THR A 1 350 ? 150.066 148.447 163.277 1.00 57.58  ?  339 THR A CG2 1 
ATOM   2420  N N   . VAL A 1 351 ? 150.781 144.873 160.023 1.00 54.65  ?  340 VAL A N   1 
ATOM   2421  C CA  . VAL A 1 351 ? 151.272 144.426 158.722 1.00 54.65  ?  340 VAL A CA  1 
ATOM   2422  C C   . VAL A 1 351 ? 150.327 144.812 157.593 1.00 54.65  ?  340 VAL A C   1 
ATOM   2423  O O   . VAL A 1 351 ? 150.752 145.418 156.614 1.00 54.65  ?  340 VAL A O   1 
ATOM   2424  C CB  . VAL A 1 351 ? 151.492 142.902 158.692 1.00 54.65  ?  340 VAL A CB  1 
ATOM   2425  C CG1 . VAL A 1 351 ? 151.977 142.464 157.321 1.00 54.65  ?  340 VAL A CG1 1 
ATOM   2426  C CG2 . VAL A 1 351 ? 152.482 142.485 159.766 1.00 54.65  ?  340 VAL A CG2 1 
ATOM   2427  N N   . GLY A 1 352 ? 149.052 144.472 157.724 1.00 53.14  ?  341 GLY A N   1 
ATOM   2428  C CA  . GLY A 1 352 ? 148.076 144.795 156.700 1.00 53.14  ?  341 GLY A CA  1 
ATOM   2429  C C   . GLY A 1 352 ? 147.952 146.284 156.490 1.00 53.14  ?  341 GLY A C   1 
ATOM   2430  O O   . GLY A 1 352 ? 147.905 146.751 155.356 1.00 53.14  ?  341 GLY A O   1 
ATOM   2431  N N   . ASP A 1 353 ? 147.917 147.036 157.579 1.00 52.74  ?  342 ASP A N   1 
ATOM   2432  C CA  . ASP A 1 353 ? 147.843 148.484 157.483 1.00 52.74  ?  342 ASP A CA  1 
ATOM   2433  C C   . ASP A 1 353 ? 149.060 149.050 156.775 1.00 52.74  ?  342 ASP A C   1 
ATOM   2434  O O   . ASP A 1 353 ? 148.937 149.951 155.957 1.00 52.74  ?  342 ASP A O   1 
ATOM   2435  C CB  . ASP A 1 353 ? 147.736 149.099 158.871 1.00 52.74  ?  342 ASP A CB  1 
ATOM   2436  C CG  . ASP A 1 353 ? 146.520 148.622 159.628 1.00 52.74  ?  342 ASP A CG  1 
ATOM   2437  O OD1 . ASP A 1 353 ? 146.513 148.737 160.870 1.00 52.74  ?  342 ASP A OD1 1 
ATOM   2438  O OD2 . ASP A 1 353 ? 145.575 148.124 158.983 1.00 52.74  -1 342 ASP A OD2 1 
ATOM   2439  N N   . CYS A 1 354 ? 150.237 148.529 157.092 1.00 50.69  ?  343 CYS A N   1 
ATOM   2440  C CA  . CYS A 1 354 ? 151.467 149.037 156.491 1.00 50.69  ?  343 CYS A CA  1 
ATOM   2441  C C   . CYS A 1 354 ? 151.520 148.739 155.003 1.00 50.69  ?  343 CYS A C   1 
ATOM   2442  O O   . CYS A 1 354 ? 152.014 149.550 154.231 1.00 50.69  ?  343 CYS A O   1 
ATOM   2443  C CB  . CYS A 1 354 ? 152.689 148.479 157.218 1.00 50.69  ?  343 CYS A CB  1 
ATOM   2444  S SG  . CYS A 1 354 ? 152.922 149.154 158.874 1.00 50.69  ?  343 CYS A SG  1 
ATOM   2445  N N   . PHE A 1 355 ? 151.008 147.585 154.594 1.00 49.15  ?  344 PHE A N   1 
ATOM   2446  C CA  . PHE A 1 355 ? 150.949 147.269 153.176 1.00 49.15  ?  344 PHE A CA  1 
ATOM   2447  C C   . PHE A 1 355 ? 150.051 148.256 152.456 1.00 49.15  ?  344 PHE A C   1 
ATOM   2448  O O   . PHE A 1 355 ? 150.379 148.707 151.366 1.00 49.15  ?  344 PHE A O   1 
ATOM   2449  C CB  . PHE A 1 355 ? 150.450 145.839 152.949 1.00 49.15  ?  344 PHE A CB  1 
ATOM   2450  C CG  . PHE A 1 355 ? 151.548 144.825 152.872 1.00 49.15  ?  344 PHE A CG  1 
ATOM   2451  C CD1 . PHE A 1 355 ? 152.237 144.627 151.688 1.00 49.15  ?  344 PHE A CD1 1 
ATOM   2452  C CD2 . PHE A 1 355 ? 151.893 144.071 153.978 1.00 49.15  ?  344 PHE A CD2 1 
ATOM   2453  C CE1 . PHE A 1 355 ? 153.251 143.694 151.609 1.00 49.15  ?  344 PHE A CE1 1 
ATOM   2454  C CE2 . PHE A 1 355 ? 152.907 143.137 153.906 1.00 49.15  ?  344 PHE A CE2 1 
ATOM   2455  C CZ  . PHE A 1 355 ? 153.588 142.949 152.720 1.00 49.15  ?  344 PHE A CZ  1 
ATOM   2456  N N   . GLY A 1 356 ? 148.914 148.582 153.057 1.00 47.71  ?  345 GLY A N   1 
ATOM   2457  C CA  . GLY A 1 356 ? 148.000 149.536 152.463 1.00 47.71  ?  345 GLY A CA  1 
ATOM   2458  C C   . GLY A 1 356 ? 148.585 150.919 152.406 1.00 47.71  ?  345 GLY A C   1 
ATOM   2459  O O   . GLY A 1 356 ? 148.448 151.604 151.404 1.00 47.71  ?  345 GLY A O   1 
ATOM   2460  N N   . ILE A 1 357 ? 149.251 151.330 153.475 1.00 45.50  ?  346 ILE A N   1 
ATOM   2461  C CA  . ILE A 1 357 ? 149.886 152.636 153.503 1.00 45.50  ?  346 ILE A CA  1 
ATOM   2462  C C   . ILE A 1 357 ? 150.930 152.701 152.404 1.00 45.50  ?  346 ILE A C   1 
ATOM   2463  O O   . ILE A 1 357 ? 151.064 153.718 151.736 1.00 45.50  ?  346 ILE A O   1 
ATOM   2464  C CB  . ILE A 1 357 ? 150.488 152.921 154.887 1.00 45.50  ?  346 ILE A CB  1 
ATOM   2465  C CG1 . ILE A 1 357 ? 149.354 153.123 155.894 1.00 45.50  ?  346 ILE A CG1 1 
ATOM   2466  C CG2 . ILE A 1 357 ? 151.400 154.135 154.845 1.00 45.50  ?  346 ILE A CG2 1 
ATOM   2467  C CD1 . ILE A 1 357 ? 149.791 153.152 157.338 1.00 45.50  ?  346 ILE A CD1 1 
ATOM   2468  N N   . ALA A 1 358 ? 151.641 151.605 152.187 1.00 45.51  ?  347 ALA A N   1 
ATOM   2469  C CA  . ALA A 1 358 ? 152.628 151.552 151.119 1.00 45.51  ?  347 ALA A CA  1 
ATOM   2470  C C   . ALA A 1 358 ? 152.019 151.559 149.693 1.00 45.51  ?  347 ALA A C   1 
ATOM   2471  O O   . ALA A 1 358 ? 152.563 152.221 148.817 1.00 45.51  ?  347 ALA A O   1 
ATOM   2472  C CB  . ALA A 1 358 ? 153.534 150.344 151.317 1.00 45.51  ?  347 ALA A CB  1 
ATOM   2473  N N   . MET A 1 359 ? 150.915 150.840 149.451 1.00 47.58  ?  348 MET A N   1 
ATOM   2474  C CA  . MET A 1 359 ? 150.308 150.832 148.125 1.00 47.58  ?  348 MET A CA  1 
ATOM   2475  C C   . MET A 1 359 ? 149.667 152.174 147.793 1.00 47.58  ?  348 MET A C   1 
ATOM   2476  O O   . MET A 1 359 ? 149.843 152.688 146.682 1.00 47.58  ?  348 MET A O   1 
ATOM   2477  C CB  . MET A 1 359 ? 149.292 149.699 148.026 1.00 47.58  ?  348 MET A CB  1 
ATOM   2478  C CG  . MET A 1 359 ? 149.939 148.324 147.964 1.00 47.58  ?  348 MET A CG  1 
ATOM   2479  S SD  . MET A 1 359 ? 151.082 148.149 146.575 1.00 47.58  ?  348 MET A SD  1 
ATOM   2480  C CE  . MET A 1 359 ? 152.668 148.083 147.405 1.00 47.58  ?  348 MET A CE  1 
ATOM   2481  N N   . VAL A 1 360 ? 148.938 152.770 148.739 1.00 46.20  ?  349 VAL A N   1 
ATOM   2482  C CA  . VAL A 1 360 ? 148.310 154.063 148.472 1.00 46.20  ?  349 VAL A CA  1 
ATOM   2483  C C   . VAL A 1 360 ? 149.366 155.142 148.270 1.00 46.20  ?  349 VAL A C   1 
ATOM   2484  O O   . VAL A 1 360 ? 149.237 156.001 147.388 1.00 46.20  ?  349 VAL A O   1 
ATOM   2485  C CB  . VAL A 1 360 ? 147.334 154.425 149.606 1.00 46.20  ?  349 VAL A CB  1 
ATOM   2486  C CG1 . VAL A 1 360 ? 146.908 155.877 149.503 1.00 46.20  ?  349 VAL A CG1 1 
ATOM   2487  C CG2 . VAL A 1 360 ? 146.126 153.523 149.565 1.00 46.20  ?  349 VAL A CG2 1 
ATOM   2488  N N   . ALA A 1 361 ? 150.426 155.118 149.080 1.00 44.68  ?  350 ALA A N   1 
ATOM   2489  C CA  . ALA A 1 361 ? 151.501 156.091 148.941 1.00 44.68  ?  350 ALA A CA  1 
ATOM   2490  C C   . ALA A 1 361 ? 152.137 156.013 147.563 1.00 44.68  ?  350 ALA A C   1 
ATOM   2491  O O   . ALA A 1 361 ? 152.306 157.035 146.883 1.00 44.68  ?  350 ALA A O   1 
ATOM   2492  C CB  . ALA A 1 361 ? 152.548 155.864 150.030 1.00 44.68  ?  350 ALA A CB  1 
ATOM   2493  N N   . PHE A 1 362 ? 152.494 154.801 147.125 1.00 45.16  ?  351 PHE A N   1 
ATOM   2494  C CA  . PHE A 1 362 ? 153.103 154.662 145.809 1.00 45.16  ?  351 PHE A CA  1 
ATOM   2495  C C   . PHE A 1 362 ? 152.142 155.078 144.706 1.00 45.16  ?  351 PHE A C   1 
ATOM   2496  O O   . PHE A 1 362 ? 152.548 155.746 143.752 1.00 45.16  ?  351 PHE A O   1 
ATOM   2497  C CB  . PHE A 1 362 ? 153.582 153.234 145.575 1.00 45.16  ?  351 PHE A CB  1 
ATOM   2498  C CG  . PHE A 1 362 ? 154.202 153.030 144.222 1.00 45.16  ?  351 PHE A CG  1 
ATOM   2499  C CD1 . PHE A 1 362 ? 155.160 153.909 143.750 1.00 45.16  ?  351 PHE A CD1 1 
ATOM   2500  C CD2 . PHE A 1 362 ? 153.819 151.975 143.417 1.00 45.16  ?  351 PHE A CD2 1 
ATOM   2501  C CE1 . PHE A 1 362 ? 155.724 153.735 142.514 1.00 45.16  ?  351 PHE A CE1 1 
ATOM   2502  C CE2 . PHE A 1 362 ? 154.388 151.799 142.178 1.00 45.16  ?  351 PHE A CE2 1 
ATOM   2503  C CZ  . PHE A 1 362 ? 155.337 152.681 141.728 1.00 45.16  ?  351 PHE A CZ  1 
ATOM   2504  N N   . ALA A 1 363 ? 150.865 154.706 144.813 1.00 45.45  ?  352 ALA A N   1 
ATOM   2505  C CA  . ALA A 1 363 ? 149.916 155.044 143.757 1.00 45.45  ?  352 ALA A CA  1 
ATOM   2506  C C   . ALA A 1 363 ? 149.765 156.552 143.612 1.00 45.45  ?  352 ALA A C   1 
ATOM   2507  O O   . ALA A 1 363 ? 149.795 157.086 142.497 1.00 45.45  ?  352 ALA A O   1 
ATOM   2508  C CB  . ALA A 1 363 ? 148.566 154.392 144.036 1.00 45.45  ?  352 ALA A CB  1 
ATOM   2509  N N   . VAL A 1 364 ? 149.620 157.261 144.733 1.00 45.47  ?  353 VAL A N   1 
ATOM   2510  C CA  . VAL A 1 364 ? 149.450 158.708 144.676 1.00 45.47  ?  353 VAL A CA  1 
ATOM   2511  C C   . VAL A 1 364 ? 150.706 159.377 144.131 1.00 45.47  ?  353 VAL A C   1 
ATOM   2512  O O   . VAL A 1 364 ? 150.638 160.224 143.226 1.00 45.47  ?  353 VAL A O   1 
ATOM   2513  C CB  . VAL A 1 364 ? 149.070 159.255 146.062 1.00 45.47  ?  353 VAL A CB  1 
ATOM   2514  C CG1 . VAL A 1 364 ? 149.327 160.745 146.134 1.00 45.47  ?  353 VAL A CG1 1 
ATOM   2515  C CG2 . VAL A 1 364 ? 147.617 158.948 146.361 1.00 45.47  ?  353 VAL A CG2 1 
ATOM   2516  N N   . ALA A 1 365 ? 151.872 159.017 144.678 1.00 45.28  ?  354 ALA A N   1 
ATOM   2517  C CA  . ALA A 1 365 ? 153.108 159.642 144.225 1.00 45.28  ?  354 ALA A CA  1 
ATOM   2518  C C   . ALA A 1 365 ? 153.350 159.378 142.749 1.00 45.28  ?  354 ALA A C   1 
ATOM   2519  O O   . ALA A 1 365 ? 153.787 160.272 142.018 1.00 45.28  ?  354 ALA A O   1 
ATOM   2520  C CB  . ALA A 1 365 ? 154.289 159.146 145.055 1.00 45.28  ?  354 ALA A CB  1 
ATOM   2521  N N   . PHE A 1 366 ? 153.053 158.164 142.281 1.00 45.45  ?  355 PHE A N   1 
ATOM   2522  C CA  . PHE A 1 366 ? 153.277 157.856 140.878 1.00 45.45  ?  355 PHE A CA  1 
ATOM   2523  C C   . PHE A 1 366 ? 152.295 158.583 139.976 1.00 45.45  ?  355 PHE A C   1 
ATOM   2524  O O   . PHE A 1 366 ? 152.676 159.010 138.887 1.00 45.45  ?  355 PHE A O   1 
ATOM   2525  C CB  . PHE A 1 366 ? 153.196 156.353 140.638 1.00 45.45  ?  355 PHE A CB  1 
ATOM   2526  C CG  . PHE A 1 366 ? 153.924 155.910 139.408 1.00 45.45  ?  355 PHE A CG  1 
ATOM   2527  C CD1 . PHE A 1 366 ? 153.231 155.465 138.298 1.00 45.45  ?  355 PHE A CD1 1 
ATOM   2528  C CD2 . PHE A 1 366 ? 155.301 155.963 139.354 1.00 45.45  ?  355 PHE A CD2 1 
ATOM   2529  C CE1 . PHE A 1 366 ? 153.903 155.073 137.166 1.00 45.45  ?  355 PHE A CE1 1 
ATOM   2530  C CE2 . PHE A 1 366 ? 155.971 155.571 138.227 1.00 45.45  ?  355 PHE A CE2 1 
ATOM   2531  C CZ  . PHE A 1 366 ? 155.273 155.126 137.132 1.00 45.45  ?  355 PHE A CZ  1 
ATOM   2532  N N   . SER A 1 367 ? 151.044 158.755 140.406 1.00 46.37  ?  356 SER A N   1 
ATOM   2533  C CA  . SER A 1 367 ? 150.105 159.532 139.605 1.00 46.37  ?  356 SER A CA  1 
ATOM   2534  C C   . SER A 1 367 ? 150.579 160.969 139.437 1.00 46.37  ?  356 SER A C   1 
ATOM   2535  O O   . SER A 1 367 ? 150.615 161.498 138.317 1.00 46.37  ?  356 SER A O   1 
ATOM   2536  C CB  . SER A 1 367 ? 148.718 159.489 140.237 1.00 46.37  ?  356 SER A CB  1 
ATOM   2537  O OG  . SER A 1 367 ? 148.451 158.208 140.776 1.00 46.37  ?  356 SER A OG  1 
ATOM   2538  N N   . VAL A 1 368 ? 150.962 161.618 140.539 1.00 47.17  ?  357 VAL A N   1 
ATOM   2539  C CA  . VAL A 1 368 ? 151.398 163.013 140.449 1.00 47.17  ?  357 VAL A CA  1 
ATOM   2540  C C   . VAL A 1 368 ? 152.673 163.121 139.616 1.00 47.17  ?  357 VAL A C   1 
ATOM   2541  O O   . VAL A 1 368 ? 152.801 163.981 138.726 1.00 47.17  ?  357 VAL A O   1 
ATOM   2542  C CB  . VAL A 1 368 ? 151.588 163.609 141.854 1.00 47.17  ?  357 VAL A CB  1 
ATOM   2543  C CG1 . VAL A 1 368 ? 151.766 165.106 141.771 1.00 47.17  ?  357 VAL A CG1 1 
ATOM   2544  C CG2 . VAL A 1 368 ? 150.408 163.277 142.735 1.00 47.17  ?  357 VAL A CG2 1 
ATOM   2545  N N   . ALA A 1 369 ? 153.632 162.274 139.943 1.00 47.99  ?  358 ALA A N   1 
ATOM   2546  C CA  . ALA A 1 369 ? 154.902 162.273 139.268 1.00 47.99  ?  358 ALA A CA  1 
ATOM   2547  C C   . ALA A 1 369 ? 154.723 162.087 137.787 1.00 47.99  ?  358 ALA A C   1 
ATOM   2548  O O   . ALA A 1 369 ? 155.479 162.630 137.006 1.00 47.99  ?  358 ALA A O   1 
ATOM   2549  C CB  . ALA A 1 369 ? 155.787 161.182 139.834 1.00 47.99  ?  358 ALA A CB  1 
ATOM   2550  N N   . SER A 1 370 ? 153.707 161.324 137.407 1.00 48.39  ?  359 SER A N   1 
ATOM   2551  C CA  . SER A 1 370 ? 153.422 161.023 136.011 1.00 48.39  ?  359 SER A CA  1 
ATOM   2552  C C   . SER A 1 370 ? 152.742 162.148 135.270 1.00 48.39  ?  359 SER A C   1 
ATOM   2553  O O   . SER A 1 370 ? 152.730 162.172 134.054 1.00 48.39  ?  359 SER A O   1 
ATOM   2554  C CB  . SER A 1 370 ? 152.561 159.778 135.915 1.00 48.39  ?  359 SER A CB  1 
ATOM   2555  O OG  . SER A 1 370 ? 153.195 158.702 136.557 1.00 48.39  ?  359 SER A OG  1 
ATOM   2556  N N   . VAL A 1 371 ? 152.165 163.078 136.005 1.00 48.79  ?  360 VAL A N   1 
ATOM   2557  C CA  . VAL A 1 371 ? 151.493 164.201 135.398 1.00 48.79  ?  360 VAL A CA  1 
ATOM   2558  C C   . VAL A 1 371 ? 152.513 165.232 134.976 1.00 48.79  ?  360 VAL A C   1 
ATOM   2559  O O   . VAL A 1 371 ? 152.269 165.995 134.063 1.00 48.79  ?  360 VAL A O   1 
ATOM   2560  C CB  . VAL A 1 371 ? 150.516 164.860 136.378 1.00 48.79  ?  360 VAL A CB  1 
ATOM   2561  C CG1 . VAL A 1 371 ? 150.128 166.240 135.894 1.00 48.79  ?  360 VAL A CG1 1 
ATOM   2562  C CG2 . VAL A 1 371 ? 149.295 163.986 136.573 1.00 48.79  ?  360 VAL A CG2 1 
ATOM   2563  N N   . TYR A 1 372 ? 153.660 165.242 135.645 1.00 51.17  ?  361 TYR A N   1 
ATOM   2564  C CA  . TYR A 1 372 ? 154.724 166.196 135.370 1.00 51.17  ?  361 TYR A CA  1 
ATOM   2565  C C   . TYR A 1 372 ? 155.821 165.626 134.504 1.00 51.17  ?  361 TYR A C   1 
ATOM   2566  O O   . TYR A 1 372 ? 156.588 166.370 133.929 1.00 51.17  ?  361 TYR A O   1 
ATOM   2567  C CB  . TYR A 1 372 ? 155.306 166.737 136.668 1.00 51.17  ?  361 TYR A CB  1 
ATOM   2568  C CG  . TYR A 1 372 ? 154.305 167.483 137.497 1.00 51.17  ?  361 TYR A CG  1 
ATOM   2569  C CD1 . TYR A 1 372 ? 153.697 168.624 137.014 1.00 51.17  ?  361 TYR A CD1 1 
ATOM   2570  C CD2 . TYR A 1 372 ? 153.967 167.049 138.761 1.00 51.17  ?  361 TYR A CD2 1 
ATOM   2571  C CE1 . TYR A 1 372 ? 152.773 169.308 137.764 1.00 51.17  ?  361 TYR A CE1 1 
ATOM   2572  C CE2 . TYR A 1 372 ? 153.047 167.734 139.522 1.00 51.17  ?  361 TYR A CE2 1 
ATOM   2573  C CZ  . TYR A 1 372 ? 152.457 168.860 139.014 1.00 51.17  ?  361 TYR A CZ  1 
ATOM   2574  O OH  . TYR A 1 372 ? 151.537 169.543 139.758 1.00 51.17  ?  361 TYR A OH  1 
ATOM   2575  N N   . SER A 1 373 ? 155.924 164.305 134.441 1.00 52.15  ?  362 SER A N   1 
ATOM   2576  C CA  . SER A 1 373 ? 156.907 163.660 133.584 1.00 52.15  ?  362 SER A CA  1 
ATOM   2577  C C   . SER A 1 373 ? 156.410 163.905 132.195 1.00 52.15  ?  362 SER A C   1 
ATOM   2578  O O   . SER A 1 373 ? 157.153 164.296 131.304 1.00 52.15  ?  362 SER A O   1 
ATOM   2579  C CB  . SER A 1 373 ? 156.927 162.162 133.810 1.00 52.15  ?  362 SER A CB  1 
ATOM   2580  O OG  . SER A 1 373 ? 157.062 161.867 135.175 1.00 52.15  ?  362 SER A OG  1 
ATOM   2581  N N   . LEU A 1 374 ? 155.126 163.649 132.022 1.00 52.78  ?  363 LEU A N   1 
ATOM   2582  C CA  . LEU A 1 374 ? 154.451 163.846 130.775 1.00 52.78  ?  363 LEU A CA  1 
ATOM   2583  C C   . LEU A 1 374 ? 154.434 165.323 130.450 1.00 52.78  ?  363 LEU A C   1 
ATOM   2584  O O   . LEU A 1 374 ? 154.761 165.703 129.344 1.00 52.78  ?  363 LEU A O   1 
ATOM   2585  C CB  . LEU A 1 374 ? 153.032 163.318 130.885 1.00 52.78  ?  363 LEU A CB  1 
ATOM   2586  C CG  . LEU A 1 374 ? 152.218 163.286 129.605 1.00 52.78  ?  363 LEU A CG  1 
ATOM   2587  C CD1 . LEU A 1 374 ? 152.816 162.296 128.628 1.00 52.78  ?  363 LEU A CD1 1 
ATOM   2588  C CD2 . LEU A 1 374 ? 150.790 162.906 129.940 1.00 52.78  ?  363 LEU A CD2 1 
ATOM   2589  N N   . LYS A 1 375 ? 154.079 166.174 131.407 1.00 54.55  ?  364 LYS A N   1 
ATOM   2590  C CA  . LYS A 1 375 ? 154.028 167.596 131.089 1.00 54.55  ?  364 LYS A CA  1 
ATOM   2591  C C   . LYS A 1 375 ? 155.392 168.133 130.672 1.00 54.55  ?  364 LYS A C   1 
ATOM   2592  O O   . LYS A 1 375 ? 155.474 169.032 129.829 1.00 54.55  ?  364 LYS A O   1 
ATOM   2593  C CB  . LYS A 1 375 ? 153.489 168.378 132.284 1.00 54.55  ?  364 LYS A CB  1 
ATOM   2594  C CG  . LYS A 1 375 ? 153.319 169.863 132.039 1.00 54.55  ?  364 LYS A CG  1 
ATOM   2595  C CD  . LYS A 1 375 ? 152.690 170.535 133.239 1.00 54.55  ?  364 LYS A CD  1 
ATOM   2596  C CE  . LYS A 1 375 ? 152.068 171.863 132.864 1.00 54.55  ?  364 LYS A CE  1 
ATOM   2597  N NZ  . LYS A 1 375 ? 153.088 172.909 132.618 1.00 54.55  1  364 LYS A NZ  1 
ATOM   2598  N N   . TYR A 1 376 ? 156.474 167.608 131.246 1.00 54.78  ?  365 TYR A N   1 
ATOM   2599  C CA  . TYR A 1 376 ? 157.806 168.136 130.979 1.00 54.78  ?  365 TYR A CA  1 
ATOM   2600  C C   . TYR A 1 376 ? 158.720 167.147 130.269 1.00 54.78  ?  365 TYR A C   1 
ATOM   2601  O O   . TYR A 1 376 ? 159.897 167.455 130.055 1.00 54.78  ?  365 TYR A O   1 
ATOM   2602  C CB  . TYR A 1 376 ? 158.450 168.616 132.279 1.00 54.78  ?  365 TYR A CB  1 
ATOM   2603  C CG  . TYR A 1 376 ? 157.672 169.729 132.931 1.00 54.78  ?  365 TYR A CG  1 
ATOM   2604  C CD1 . TYR A 1 376 ? 156.723 169.457 133.898 1.00 54.78  ?  365 TYR A CD1 1 
ATOM   2605  C CD2 . TYR A 1 376 ? 157.865 171.047 132.559 1.00 54.78  ?  365 TYR A CD2 1 
ATOM   2606  C CE1 . TYR A 1 376 ? 156.003 170.460 134.482 1.00 54.78  ?  365 TYR A CE1 1 
ATOM   2607  C CE2 . TYR A 1 376 ? 157.149 172.058 133.142 1.00 54.78  ?  365 TYR A CE2 1 
ATOM   2608  C CZ  . TYR A 1 376 ? 156.219 171.758 134.105 1.00 54.78  ?  365 TYR A CZ  1 
ATOM   2609  O OH  . TYR A 1 376 ? 155.494 172.760 134.696 1.00 54.78  ?  365 TYR A OH  1 
ATOM   2610  N N   . ASP A 1 377 ? 158.211 165.973 129.898 1.00 56.71  ?  366 ASP A N   1 
ATOM   2611  C CA  . ASP A 1 377 ? 158.894 165.056 128.983 1.00 56.71  ?  366 ASP A CA  1 
ATOM   2612  C C   . ASP A 1 377 ? 160.251 164.607 129.527 1.00 56.71  ?  366 ASP A C   1 
ATOM   2613  O O   . ASP A 1 377 ? 161.310 164.947 128.998 1.00 56.71  ?  366 ASP A O   1 
ATOM   2614  C CB  . ASP A 1 377 ? 159.039 165.696 127.599 1.00 56.71  ?  366 ASP A CB  1 
ATOM   2615  C CG  . ASP A 1 377 ? 159.328 164.680 126.510 1.00 56.71  ?  366 ASP A CG  1 
ATOM   2616  O OD1 . ASP A 1 377 ? 160.286 163.896 126.651 1.00 56.71  ?  366 ASP A OD1 1 
ATOM   2617  O OD2 . ASP A 1 377 ? 158.584 164.664 125.508 1.00 56.71  -1 366 ASP A OD2 1 
ATOM   2618  N N   . TYR A 1 378 ? 160.206 163.845 130.616 1.00 53.42  ?  367 TYR A N   1 
ATOM   2619  C CA  . TYR A 1 378 ? 161.382 163.155 131.121 1.00 53.42  ?  367 TYR A CA  1 
ATOM   2620  C C   . TYR A 1 378 ? 160.959 161.802 131.674 1.00 53.42  ?  367 TYR A C   1 
ATOM   2621  O O   . TYR A 1 378 ? 159.832 161.654 132.159 1.00 53.42  ?  367 TYR A O   1 
ATOM   2622  C CB  . TYR A 1 378 ? 162.117 163.969 132.198 1.00 53.42  ?  367 TYR A CB  1 
ATOM   2623  C CG  . TYR A 1 378 ? 161.273 164.445 133.357 1.00 53.42  ?  367 TYR A CG  1 
ATOM   2624  C CD1 . TYR A 1 378 ? 160.771 165.731 133.387 1.00 53.42  ?  367 TYR A CD1 1 
ATOM   2625  C CD2 . TYR A 1 378 ? 161.007 163.615 134.434 1.00 53.42  ?  367 TYR A CD2 1 
ATOM   2626  C CE1 . TYR A 1 378 ? 160.013 166.166 134.443 1.00 53.42  ?  367 TYR A CE1 1 
ATOM   2627  C CE2 . TYR A 1 378 ? 160.250 164.045 135.489 1.00 53.42  ?  367 TYR A CE2 1 
ATOM   2628  C CZ  . TYR A 1 378 ? 159.758 165.320 135.491 1.00 53.42  ?  367 TYR A CZ  1 
ATOM   2629  O OH  . TYR A 1 378 ? 159.002 165.749 136.549 1.00 53.42  ?  367 TYR A OH  1 
ATOM   2630  N N   . PRO A 1 379 ? 161.830 160.800 131.603 1.00 52.83  ?  368 PRO A N   1 
ATOM   2631  C CA  . PRO A 1 379 ? 161.437 159.449 132.006 1.00 52.83  ?  368 PRO A CA  1 
ATOM   2632  C C   . PRO A 1 379 ? 161.352 159.286 133.514 1.00 52.83  ?  368 PRO A C   1 
ATOM   2633  O O   . PRO A 1 379 ? 162.166 159.813 134.274 1.00 52.83  ?  368 PRO A O   1 
ATOM   2634  C CB  . PRO A 1 379 ? 162.551 158.574 131.420 1.00 52.83  ?  368 PRO A CB  1 
ATOM   2635  C CG  . PRO A 1 379 ? 163.725 159.468 131.359 1.00 52.83  ?  368 PRO A CG  1 
ATOM   2636  C CD  . PRO A 1 379 ? 163.194 160.833 131.049 1.00 52.83  ?  368 PRO A CD  1 
ATOM   2637  N N   . LEU A 1 380 ? 160.346 158.528 133.939 1.00 51.25  ?  369 LEU A N   1 
ATOM   2638  C CA  . LEU A 1 380 ? 160.042 158.322 135.350 1.00 51.25  ?  369 LEU A CA  1 
ATOM   2639  C C   . LEU A 1 380 ? 160.103 156.830 135.651 1.00 51.25  ?  369 LEU A C   1 
ATOM   2640  O O   . LEU A 1 380 ? 159.227 156.070 135.229 1.00 51.25  ?  369 LEU A O   1 
ATOM   2641  C CB  . LEU A 1 380 ? 158.670 158.896 135.690 1.00 51.25  ?  369 LEU A CB  1 
ATOM   2642  C CG  . LEU A 1 380 ? 158.346 159.108 137.162 1.00 51.25  ?  369 LEU A CG  1 
ATOM   2643  C CD1 . LEU A 1 380 ? 158.686 160.518 137.560 1.00 51.25  ?  369 LEU A CD1 1 
ATOM   2644  C CD2 . LEU A 1 380 ? 156.885 158.820 137.403 1.00 51.25  ?  369 LEU A CD2 1 
ATOM   2645  N N   . ASP A 1 381 ? 161.133 156.418 136.385 1.00 51.17  ?  370 ASP A N   1 
ATOM   2646  C CA  . ASP A 1 381 ? 161.301 155.025 136.774 1.00 51.17  ?  370 ASP A CA  1 
ATOM   2647  C C   . ASP A 1 381 ? 160.387 154.713 137.948 1.00 51.17  ?  370 ASP A C   1 
ATOM   2648  O O   . ASP A 1 381 ? 160.470 155.369 138.988 1.00 51.17  ?  370 ASP A O   1 
ATOM   2649  C CB  . ASP A 1 381 ? 162.758 154.758 137.142 1.00 51.17  ?  370 ASP A CB  1 
ATOM   2650  C CG  . ASP A 1 381 ? 163.122 153.292 137.079 1.00 51.17  ?  370 ASP A CG  1 
ATOM   2651  O OD1 . ASP A 1 381 ? 162.262 152.477 136.690 1.00 51.17  ?  370 ASP A OD1 1 
ATOM   2652  O OD2 . ASP A 1 381 ? 164.275 152.954 137.417 1.00 51.17  -1 370 ASP A OD2 1 
ATOM   2653  N N   . GLY A 1 382 ? 159.520 153.712 137.792 1.00 48.38  ?  371 GLY A N   1 
ATOM   2654  C CA  . GLY A 1 382 ? 158.604 153.373 138.869 1.00 48.38  ?  371 GLY A CA  1 
ATOM   2655  C C   . GLY A 1 382 ? 159.276 152.605 139.987 1.00 48.38  ?  371 GLY A C   1 
ATOM   2656  O O   . GLY A 1 382 ? 158.931 152.767 141.163 1.00 48.38  ?  371 GLY A O   1 
ATOM   2657  N N   . ASN A 1 383 ? 160.256 151.771 139.644 1.00 48.38  ?  372 ASN A N   1 
ATOM   2658  C CA  . ASN A 1 383 ? 160.971 151.017 140.666 1.00 48.38  ?  372 ASN A CA  1 
ATOM   2659  C C   . ASN A 1 383 ? 161.887 151.923 141.474 1.00 48.38  ?  372 ASN A C   1 
ATOM   2660  O O   . ASN A 1 383 ? 162.047 151.731 142.683 1.00 48.38  ?  372 ASN A O   1 
ATOM   2661  C CB  . ASN A 1 383 ? 161.763 149.886 140.020 1.00 48.38  ?  372 ASN A CB  1 
ATOM   2662  C CG  . ASN A 1 383 ? 160.939 149.097 139.038 1.00 48.38  ?  372 ASN A CG  1 
ATOM   2663  O OD1 . ASN A 1 383 ? 159.968 148.450 139.411 1.00 48.38  ?  372 ASN A OD1 1 
ATOM   2664  N ND2 . ASN A 1 383 ? 161.316 149.154 137.771 1.00 48.38  ?  372 ASN A ND2 1 
ATOM   2665  N N   . GLN A 1 384 ? 162.484 152.927 140.834 1.00 50.13  ?  373 GLN A N   1 
ATOM   2666  C CA  . GLN A 1 384 ? 163.246 153.905 141.597 1.00 50.13  ?  373 GLN A CA  1 
ATOM   2667  C C   . GLN A 1 384 ? 162.334 154.796 142.423 1.00 50.13  ?  373 GLN A C   1 
ATOM   2668  O O   . GLN A 1 384 ? 162.731 155.259 143.494 1.00 50.13  ?  373 GLN A O   1 
ATOM   2669  C CB  . GLN A 1 384 ? 164.122 154.746 140.676 1.00 50.13  ?  373 GLN A CB  1 
ATOM   2670  C CG  . GLN A 1 384 ? 165.200 155.516 141.414 1.00 50.13  ?  373 GLN A CG  1 
ATOM   2671  C CD  . GLN A 1 384 ? 166.137 154.610 142.175 1.00 50.13  ?  373 GLN A CD  1 
ATOM   2672  O OE1 . GLN A 1 384 ? 166.360 153.468 141.787 1.00 50.13  ?  373 GLN A OE1 1 
ATOM   2673  N NE2 . GLN A 1 384 ? 166.693 155.113 143.266 1.00 50.13  ?  373 GLN A NE2 1 
ATOM   2674  N N   . GLU A 1 385 ? 161.107 155.036 141.958 1.00 48.99  ?  374 GLU A N   1 
ATOM   2675  C CA  . GLU A 1 385 ? 160.129 155.708 142.801 1.00 48.99  ?  374 GLU A CA  1 
ATOM   2676  C C   . GLU A 1 385 ? 159.881 154.913 144.070 1.00 48.99  ?  374 GLU A C   1 
ATOM   2677  O O   . GLU A 1 385 ? 159.917 155.461 145.177 1.00 48.99  ?  374 GLU A O   1 
ATOM   2678  C CB  . GLU A 1 385 ? 158.818 155.909 142.044 1.00 48.99  ?  374 GLU A CB  1 
ATOM   2679  C CG  . GLU A 1 385 ? 158.866 156.980 140.987 1.00 48.99  ?  374 GLU A CG  1 
ATOM   2680  C CD  . GLU A 1 385 ? 159.545 158.228 141.473 1.00 48.99  ?  374 GLU A CD  1 
ATOM   2681  O OE1 . GLU A 1 385 ? 158.901 159.012 142.201 1.00 48.99  ?  374 GLU A OE1 1 
ATOM   2682  O OE2 . GLU A 1 385 ? 160.727 158.430 141.134 1.00 48.99  -1 374 GLU A OE2 1 
ATOM   2683  N N   . LEU A 1 386 ? 159.623 153.613 143.925 1.00 44.55  ?  375 LEU A N   1 
ATOM   2684  C CA  . LEU A 1 386 ? 159.398 152.771 145.096 1.00 44.55  ?  375 LEU A CA  1 
ATOM   2685  C C   . LEU A 1 386 ? 160.617 152.750 146.009 1.00 44.55  ?  375 LEU A C   1 
ATOM   2686  O O   . LEU A 1 386 ? 160.483 152.829 147.232 1.00 44.55  ?  375 LEU A O   1 
ATOM   2687  C CB  . LEU A 1 386 ? 159.030 151.356 144.662 1.00 44.55  ?  375 LEU A CB  1 
ATOM   2688  C CG  . LEU A 1 386 ? 157.554 151.081 144.399 1.00 44.55  ?  375 LEU A CG  1 
ATOM   2689  C CD1 . LEU A 1 386 ? 157.385 149.805 143.618 1.00 44.55  ?  375 LEU A CD1 1 
ATOM   2690  C CD2 . LEU A 1 386 ? 156.795 151.010 145.702 1.00 44.55  ?  375 LEU A CD2 1 
ATOM   2691  N N   . ILE A 1 387 ? 161.817 152.653 145.435 1.00 46.03  ?  376 ILE A N   1 
ATOM   2692  C CA  . ILE A 1 387 ? 163.035 152.608 146.245 1.00 46.03  ?  376 ILE A CA  1 
ATOM   2693  C C   . ILE A 1 387 ? 163.206 153.900 147.033 1.00 46.03  ?  376 ILE A C   1 
ATOM   2694  O O   . ILE A 1 387 ? 163.462 153.880 148.243 1.00 46.03  ?  376 ILE A O   1 
ATOM   2695  C CB  . ILE A 1 387 ? 164.258 152.326 145.357 1.00 46.03  ?  376 ILE A CB  1 
ATOM   2696  C CG1 . ILE A 1 387 ? 164.268 150.869 144.904 1.00 46.03  ?  376 ILE A CG1 1 
ATOM   2697  C CG2 . ILE A 1 387 ? 165.540 152.658 146.095 1.00 46.03  ?  376 ILE A CG2 1 
ATOM   2698  C CD1 . ILE A 1 387 ? 165.353 150.555 143.914 1.00 46.03  ?  376 ILE A CD1 1 
ATOM   2699  N N   . ALA A 1 388 ? 163.082 155.044 146.355 1.00 44.97  ?  377 ALA A N   1 
ATOM   2700  C CA  . ALA A 1 388 ? 163.266 156.332 147.016 1.00 44.97  ?  377 ALA A CA  1 
ATOM   2701  C C   . ALA A 1 388 ? 162.217 156.563 148.091 1.00 44.97  ?  377 ALA A C   1 
ATOM   2702  O O   . ALA A 1 388 ? 162.539 157.028 149.191 1.00 44.97  ?  377 ALA A O   1 
ATOM   2703  C CB  . ALA A 1 388 ? 163.224 157.454 145.987 1.00 44.97  ?  377 ALA A CB  1 
ATOM   2704  N N   . LEU A 1 389 ? 160.954 156.236 147.803 1.00 45.07  ?  378 LEU A N   1 
ATOM   2705  C CA  . LEU A 1 389 ? 159.903 156.442 148.790 1.00 45.07  ?  378 LEU A CA  1 
ATOM   2706  C C   . LEU A 1 389 ? 160.073 155.507 149.980 1.00 45.07  ?  378 LEU A C   1 
ATOM   2707  O O   . LEU A 1 389 ? 159.844 155.907 151.125 1.00 45.07  ?  378 LEU A O   1 
ATOM   2708  C CB  . LEU A 1 389 ? 158.531 156.250 148.149 1.00 45.07  ?  378 LEU A CB  1 
ATOM   2709  C CG  . LEU A 1 389 ? 158.098 157.218 147.046 1.00 45.07  ?  378 LEU A CG  1 
ATOM   2710  C CD1 . LEU A 1 389 ? 156.741 156.813 146.514 1.00 45.07  ?  378 LEU A CD1 1 
ATOM   2711  C CD2 . LEU A 1 389 ? 158.074 158.658 147.527 1.00 45.07  ?  378 LEU A CD2 1 
ATOM   2712  N N   . GLY A 1 390 ? 160.498 154.267 149.737 1.00 45.11  ?  379 GLY A N   1 
ATOM   2713  C CA  . GLY A 1 390 ? 160.728 153.351 150.838 1.00 45.11  ?  379 GLY A CA  1 
ATOM   2714  C C   . GLY A 1 390 ? 161.883 153.776 151.720 1.00 45.11  ?  379 GLY A C   1 
ATOM   2715  O O   . GLY A 1 390 ? 161.789 153.716 152.945 1.00 45.11  ?  379 GLY A O   1 
ATOM   2716  N N   . LEU A 1 391 ? 162.988 154.214 151.116 1.00 43.58  ?  380 LEU A N   1 
ATOM   2717  C CA  . LEU A 1 391 ? 164.106 154.703 151.915 1.00 43.58  ?  380 LEU A CA  1 
ATOM   2718  C C   . LEU A 1 391 ? 163.714 155.938 152.714 1.00 43.58  ?  380 LEU A C   1 
ATOM   2719  O O   . LEU A 1 391 ? 164.073 156.067 153.892 1.00 43.58  ?  380 LEU A O   1 
ATOM   2720  C CB  . LEU A 1 391 ? 165.303 155.006 151.017 1.00 43.58  ?  380 LEU A CB  1 
ATOM   2721  C CG  . LEU A 1 391 ? 166.060 153.805 150.459 1.00 43.58  ?  380 LEU A CG  1 
ATOM   2722  C CD1 . LEU A 1 391 ? 167.090 154.260 149.457 1.00 43.58  ?  380 LEU A CD1 1 
ATOM   2723  C CD2 . LEU A 1 391 ? 166.713 153.028 151.580 1.00 43.58  ?  380 LEU A CD2 1 
ATOM   2724  N N   . GLY A 1 392 ? 162.969 156.857 152.094 1.00 43.71  ?  381 GLY A N   1 
ATOM   2725  C CA  . GLY A 1 392 ? 162.530 158.041 152.809 1.00 43.71  ?  381 GLY A CA  1 
ATOM   2726  C C   . GLY A 1 392 ? 161.618 157.717 153.970 1.00 43.71  ?  381 GLY A C   1 
ATOM   2727  O O   . GLY A 1 392 ? 161.747 158.296 155.049 1.00 43.71  ?  381 GLY A O   1 
ATOM   2728  N N   . ASN A 1 393 ? 160.697 156.773 153.776 1.00 44.75  ?  382 ASN A N   1 
ATOM   2729  C CA  . ASN A 1 393 ? 159.803 156.389 154.860 1.00 44.75  ?  382 ASN A CA  1 
ATOM   2730  C C   . ASN A 1 393 ? 160.555 155.672 155.971 1.00 44.75  ?  382 ASN A C   1 
ATOM   2731  O O   . ASN A 1 393 ? 160.263 155.876 157.150 1.00 44.75  ?  382 ASN A O   1 
ATOM   2732  C CB  . ASN A 1 393 ? 158.671 155.515 154.330 1.00 44.75  ?  382 ASN A CB  1 
ATOM   2733  C CG  . ASN A 1 393 ? 157.598 156.314 153.636 1.00 44.75  ?  382 ASN A CG  1 
ATOM   2734  O OD1 . ASN A 1 393 ? 157.660 157.536 153.583 1.00 44.75  ?  382 ASN A OD1 1 
ATOM   2735  N ND2 . ASN A 1 393 ? 156.603 155.625 153.096 1.00 44.75  ?  382 ASN A ND2 1 
ATOM   2736  N N   . ILE A 1 394 ? 161.535 154.838 155.622 1.00 44.80  ?  383 ILE A N   1 
ATOM   2737  C CA  . ILE A 1 394 ? 162.332 154.165 156.645 1.00 44.80  ?  383 ILE A CA  1 
ATOM   2738  C C   . ILE A 1 394 ? 163.071 155.186 157.501 1.00 44.80  ?  383 ILE A C   1 
ATOM   2739  O O   . ILE A 1 394 ? 163.020 155.138 158.734 1.00 44.80  ?  383 ILE A O   1 
ATOM   2740  C CB  . ILE A 1 394 ? 163.303 153.160 156.001 1.00 44.80  ?  383 ILE A CB  1 
ATOM   2741  C CG1 . ILE A 1 394 ? 162.543 151.965 155.439 1.00 44.80  ?  383 ILE A CG1 1 
ATOM   2742  C CG2 . ILE A 1 394 ? 164.318 152.681 157.012 1.00 44.80  ?  383 ILE A CG2 1 
ATOM   2743  C CD1 . ILE A 1 394 ? 163.358 151.124 154.498 1.00 44.80  ?  383 ILE A CD1 1 
ATOM   2744  N N   . VAL A 1 395 ? 163.766 156.130 156.861 1.00 46.40  ?  384 VAL A N   1 
ATOM   2745  C CA  . VAL A 1 395 ? 164.514 157.124 157.625 1.00 46.40  ?  384 VAL A CA  1 
ATOM   2746  C C   . VAL A 1 395 ? 163.581 158.011 158.443 1.00 46.40  ?  384 VAL A C   1 
ATOM   2747  O O   . VAL A 1 395 ? 163.862 158.318 159.613 1.00 46.40  ?  384 VAL A O   1 
ATOM   2748  C CB  . VAL A 1 395 ? 165.405 157.956 156.687 1.00 46.40  ?  384 VAL A CB  1 
ATOM   2749  C CG1 . VAL A 1 395 ? 166.203 158.962 157.477 1.00 46.40  ?  384 VAL A CG1 1 
ATOM   2750  C CG2 . VAL A 1 395 ? 166.334 157.053 155.911 1.00 46.40  ?  384 VAL A CG2 1 
ATOM   2751  N N   . CYS A 1 396 ? 162.457 158.430 157.860 1.00 49.04  ?  385 CYS A N   1 
ATOM   2752  C CA  . CYS A 1 396 ? 161.489 159.244 158.583 1.00 49.04  ?  385 CYS A CA  1 
ATOM   2753  C C   . CYS A 1 396 ? 160.967 158.523 159.818 1.00 49.04  ?  385 CYS A C   1 
ATOM   2754  O O   . CYS A 1 396 ? 160.936 159.095 160.912 1.00 49.04  ?  385 CYS A O   1 
ATOM   2755  C CB  . CYS A 1 396 ? 160.337 159.615 157.655 1.00 49.04  ?  385 CYS A CB  1 
ATOM   2756  S SG  . CYS A 1 396 ? 159.415 161.036 158.176 1.00 49.04  ?  385 CYS A SG  1 
ATOM   2757  N N   . GLY A 1 397 ? 160.540 157.268 159.661 1.00 48.47  ?  386 GLY A N   1 
ATOM   2758  C CA  . GLY A 1 397 ? 160.038 156.520 160.796 1.00 48.47  ?  386 GLY A CA  1 
ATOM   2759  C C   . GLY A 1 397 ? 161.092 156.255 161.849 1.00 48.47  ?  386 GLY A C   1 
ATOM   2760  O O   . GLY A 1 397 ? 160.786 156.239 163.043 1.00 48.47  ?  386 GLY A O   1 
ATOM   2761  N N   . VAL A 1 398 ? 162.342 156.040 161.434 1.00 50.11  ?  387 VAL A N   1 
ATOM   2762  C CA  . VAL A 1 398 ? 163.406 155.875 162.417 1.00 50.11  ?  387 VAL A CA  1 
ATOM   2763  C C   . VAL A 1 398 ? 163.590 157.152 163.218 1.00 50.11  ?  387 VAL A C   1 
ATOM   2764  O O   . VAL A 1 398 ? 163.820 157.106 164.430 1.00 50.11  ?  387 VAL A O   1 
ATOM   2765  C CB  . VAL A 1 398 ? 164.714 155.436 161.731 1.00 50.11  ?  387 VAL A CB  1 
ATOM   2766  C CG1 . VAL A 1 398 ? 165.885 155.559 162.679 1.00 50.11  ?  387 VAL A CG1 1 
ATOM   2767  C CG2 . VAL A 1 398 ? 164.591 154.013 161.248 1.00 50.11  ?  387 VAL A CG2 1 
ATOM   2768  N N   . PHE A 1 399 ? 163.467 158.313 162.574 1.00 50.16  ?  388 PHE A N   1 
ATOM   2769  C CA  . PHE A 1 399 ? 163.627 159.582 163.268 1.00 50.16  ?  388 PHE A CA  1 
ATOM   2770  C C   . PHE A 1 399 ? 162.296 160.191 163.703 1.00 50.16  ?  388 PHE A C   1 
ATOM   2771  O O   . PHE A 1 399 ? 162.161 161.417 163.740 1.00 50.16  ?  388 PHE A O   1 
ATOM   2772  C CB  . PHE A 1 399 ? 164.405 160.563 162.400 1.00 50.16  ?  388 PHE A CB  1 
ATOM   2773  C CG  . PHE A 1 399 ? 165.861 160.239 162.275 1.00 50.16  ?  388 PHE A CG  1 
ATOM   2774  C CD1 . PHE A 1 399 ? 166.323 159.473 161.225 1.00 50.16  ?  388 PHE A CD1 1 
ATOM   2775  C CD2 . PHE A 1 399 ? 166.768 160.706 163.203 1.00 50.16  ?  388 PHE A CD2 1 
ATOM   2776  C CE1 . PHE A 1 399 ? 167.659 159.177 161.107 1.00 50.16  ?  388 PHE A CE1 1 
ATOM   2777  C CE2 . PHE A 1 399 ? 168.103 160.412 163.089 1.00 50.16  ?  388 PHE A CE2 1 
ATOM   2778  C CZ  . PHE A 1 399 ? 168.548 159.648 162.039 1.00 50.16  ?  388 PHE A CZ  1 
ATOM   2779  N N   . ARG A 1 400 ? 161.315 159.351 164.042 1.00 54.91  ?  389 ARG A N   1 
ATOM   2780  C CA  . ARG A 1 400 ? 160.033 159.768 164.617 1.00 54.91  ?  389 ARG A CA  1 
ATOM   2781  C C   . ARG A 1 400 ? 159.235 160.658 163.659 1.00 54.91  ?  389 ARG A C   1 
ATOM   2782  O O   . ARG A 1 400 ? 158.849 161.778 163.985 1.00 54.91  ?  389 ARG A O   1 
ATOM   2783  C CB  . ARG A 1 400 ? 160.236 160.469 165.966 1.00 54.91  ?  389 ARG A CB  1 
ATOM   2784  C CG  . ARG A 1 400 ? 161.298 159.856 166.850 1.00 54.91  ?  389 ARG A CG  1 
ATOM   2785  C CD  . ARG A 1 400 ? 160.703 158.960 167.911 1.00 54.91  ?  389 ARG A CD  1 
ATOM   2786  N NE  . ARG A 1 400 ? 161.726 158.503 168.846 1.00 54.91  ?  389 ARG A NE  1 
ATOM   2787  C CZ  . ARG A 1 400 ? 161.938 159.037 170.043 1.00 54.91  ?  389 ARG A CZ  1 
ATOM   2788  N NH1 . ARG A 1 400 ? 162.895 158.558 170.823 1.00 54.91  1  389 ARG A NH1 1 
ATOM   2789  N NH2 . ARG A 1 400 ? 161.192 160.045 170.462 1.00 54.91  ?  389 ARG A NH2 1 
ATOM   2790  N N   . GLY A 1 401 ? 158.981 160.134 162.469 1.00 49.30  ?  390 GLY A N   1 
ATOM   2791  C CA  . GLY A 1 401 ? 158.067 160.781 161.549 1.00 49.30  ?  390 GLY A CA  1 
ATOM   2792  C C   . GLY A 1 401 ? 156.958 159.834 161.153 1.00 49.30  ?  390 GLY A C   1 
ATOM   2793  O O   . GLY A 1 401 ? 156.921 158.704 161.642 1.00 49.30  ?  390 GLY A O   1 
ATOM   2794  N N   . PHE A 1 402 ? 156.048 160.259 160.283 1.00 47.33  ?  391 PHE A N   1 
ATOM   2795  C CA  . PHE A 1 402 ? 155.026 159.356 159.779 1.00 47.33  ?  391 PHE A CA  1 
ATOM   2796  C C   . PHE A 1 402 ? 155.052 159.363 158.258 1.00 47.33  ?  391 PHE A C   1 
ATOM   2797  O O   . PHE A 1 402 ? 155.593 160.269 157.623 1.00 47.33  ?  391 PHE A O   1 
ATOM   2798  C CB  . PHE A 1 402 ? 153.627 159.689 160.325 1.00 47.33  ?  391 PHE A CB  1 
ATOM   2799  C CG  . PHE A 1 402 ? 153.206 161.113 160.136 1.00 47.33  ?  391 PHE A CG  1 
ATOM   2800  C CD1 . PHE A 1 402 ? 152.446 161.484 159.045 1.00 47.33  ?  391 PHE A CD1 1 
ATOM   2801  C CD2 . PHE A 1 402 ? 153.535 162.074 161.070 1.00 47.33  ?  391 PHE A CD2 1 
ATOM   2802  C CE1 . PHE A 1 402 ? 152.048 162.784 158.877 1.00 47.33  ?  391 PHE A CE1 1 
ATOM   2803  C CE2 . PHE A 1 402 ? 153.139 163.373 160.902 1.00 47.33  ?  391 PHE A CE2 1 
ATOM   2804  C CZ  . PHE A 1 402 ? 152.394 163.730 159.806 1.00 47.33  ?  391 PHE A CZ  1 
ATOM   2805  N N   . ALA A 1 403 ? 154.459 158.320 157.683 1.00 47.92  ?  392 ALA A N   1 
ATOM   2806  C CA  . ALA A 1 403 ? 154.606 158.044 156.262 1.00 47.92  ?  392 ALA A CA  1 
ATOM   2807  C C   . ALA A 1 403 ? 154.015 159.155 155.406 1.00 47.92  ?  392 ALA A C   1 
ATOM   2808  O O   . ALA A 1 403 ? 152.991 159.752 155.743 1.00 47.92  ?  392 ALA A O   1 
ATOM   2809  C CB  . ALA A 1 403 ? 153.941 156.714 155.919 1.00 47.92  ?  392 ALA A CB  1 
ATOM   2810  N N   . GLY A 1 404 ? 154.678 159.424 154.286 1.00 49.17  ?  393 GLY A N   1 
ATOM   2811  C CA  . GLY A 1 404 ? 154.160 160.346 153.297 1.00 49.17  ?  393 GLY A CA  1 
ATOM   2812  C C   . GLY A 1 404 ? 154.913 160.187 152.001 1.00 49.17  ?  393 GLY A C   1 
ATOM   2813  O O   . GLY A 1 404 ? 156.127 159.967 151.996 1.00 49.17  ?  393 GLY A O   1 
ATOM   2814  N N   . SER A 1 405 ? 154.185 160.293 150.887 1.00 48.53  ?  394 SER A N   1 
ATOM   2815  C CA  . SER A 1 405 ? 154.798 160.162 149.567 1.00 48.53  ?  394 SER A CA  1 
ATOM   2816  C C   . SER A 1 405 ? 154.758 161.437 148.736 1.00 48.53  ?  394 SER A C   1 
ATOM   2817  O O   . SER A 1 405 ? 155.807 161.886 148.276 1.00 48.53  ?  394 SER A O   1 
ATOM   2818  C CB  . SER A 1 405 ? 154.108 159.053 148.775 1.00 48.53  ?  394 SER A CB  1 
ATOM   2819  O OG  . SER A 1 405 ? 152.893 159.509 148.216 1.00 48.53  ?  394 SER A OG  1 
ATOM   2820  N N   . THR A 1 406 ? 153.592 162.046 148.546 1.00 47.86  ?  395 THR A N   1 
ATOM   2821  C CA  . THR A 1 406 ? 153.488 163.374 147.958 1.00 47.86  ?  395 THR A CA  1 
ATOM   2822  C C   . THR A 1 406 ? 152.032 163.805 147.993 1.00 47.86  ?  395 THR A C   1 
ATOM   2823  O O   . THR A 1 406 ? 151.121 162.982 147.870 1.00 47.86  ?  395 THR A O   1 
ATOM   2824  C CB  . THR A 1 406 ? 154.032 163.430 146.523 1.00 47.86  ?  395 THR A CB  1 
ATOM   2825  O OG1 . THR A 1 406 ? 154.090 164.794 146.096 1.00 47.86  ?  395 THR A OG1 1 
ATOM   2826  C CG2 . THR A 1 406 ? 153.154 162.664 145.562 1.00 47.86  ?  395 THR A CG2 1 
ATOM   2827  N N   . ALA A 1 407 ? 151.826 165.101 148.188 1.00 50.13  ?  396 ALA A N   1 
ATOM   2828  C CA  . ALA A 1 407 ? 150.506 165.710 148.128 1.00 50.13  ?  396 ALA A CA  1 
ATOM   2829  C C   . ALA A 1 407 ? 150.374 166.417 146.790 1.00 50.13  ?  396 ALA A C   1 
ATOM   2830  O O   . ALA A 1 407 ? 151.274 167.162 146.391 1.00 50.13  ?  396 ALA A O   1 
ATOM   2831  C CB  . ALA A 1 407 ? 150.295 166.685 149.285 1.00 50.13  ?  396 ALA A CB  1 
ATOM   2832  N N   . LEU A 1 408 ? 149.264 166.172 146.091 1.00 50.13  ?  397 LEU A N   1 
ATOM   2833  C CA  . LEU A 1 408 ? 149.047 166.826 144.807 1.00 50.13  ?  397 LEU A CA  1 
ATOM   2834  C C   . LEU A 1 408 ? 148.974 168.337 144.961 1.00 50.13  ?  397 LEU A C   1 
ATOM   2835  O O   . LEU A 1 408 ? 149.392 169.082 144.070 1.00 50.13  ?  397 LEU A O   1 
ATOM   2836  C CB  . LEU A 1 408 ? 147.776 166.291 144.151 1.00 50.13  ?  397 LEU A CB  1 
ATOM   2837  C CG  . LEU A 1 408 ? 147.331 166.986 142.864 1.00 50.13  ?  397 LEU A CG  1 
ATOM   2838  C CD1 . LEU A 1 408 ? 148.429 166.944 141.810 1.00 50.13  ?  397 LEU A CD1 1 
ATOM   2839  C CD2 . LEU A 1 408 ? 146.055 166.362 142.334 1.00 50.13  ?  397 LEU A CD2 1 
ATOM   2840  N N   . SER A 1 409 ? 148.514 168.835 146.102 1.00 52.49  ?  398 SER A N   1 
ATOM   2841  C CA  . SER A 1 409 ? 148.414 170.282 146.324 1.00 52.49  ?  398 SER A CA  1 
ATOM   2842  C C   . SER A 1 409 ? 149.761 170.943 146.558 1.00 52.49  ?  398 SER A C   1 
ATOM   2843  O O   . SER A 1 409 ? 149.995 172.047 146.123 1.00 52.49  ?  398 SER A O   1 
ATOM   2844  C CB  . SER A 1 409 ? 147.469 170.606 147.473 1.00 52.49  ?  398 SER A CB  1 
ATOM   2845  O OG  . SER A 1 409 ? 148.126 170.542 148.709 1.00 52.49  ?  398 SER A OG  1 
ATOM   2846  N N   . ARG A 1 410 ? 150.631 170.291 147.308 1.00 49.62  ?  399 ARG A N   1 
ATOM   2847  C CA  . ARG A 1 410 ? 151.979 170.830 147.500 1.00 49.62  ?  399 ARG A CA  1 
ATOM   2848  C C   . ARG A 1 410 ? 152.854 170.593 146.264 1.00 49.62  ?  399 ARG A C   1 
ATOM   2849  O O   . ARG A 1 410 ? 153.684 171.435 145.954 1.00 49.62  ?  399 ARG A O   1 
ATOM   2850  C CB  . ARG A 1 410 ? 152.609 170.276 148.783 1.00 49.62  ?  399 ARG A CB  1 
ATOM   2851  C CG  . ARG A 1 410 ? 153.818 171.038 149.289 1.00 49.62  ?  399 ARG A CG  1 
ATOM   2852  C CD  . ARG A 1 410 ? 154.361 170.419 150.567 1.00 49.62  ?  399 ARG A CD  1 
ATOM   2853  N NE  . ARG A 1 410 ? 154.635 168.993 150.417 1.00 49.62  ?  399 ARG A NE  1 
ATOM   2854  C CZ  . ARG A 1 410 ? 153.899 168.024 150.950 1.00 49.62  ?  399 ARG A CZ  1 
ATOM   2855  N NH1 . ARG A 1 410 ? 154.225 166.758 150.751 1.00 49.62  1  399 ARG A NH1 1 
ATOM   2856  N NH2 . ARG A 1 410 ? 152.843 168.319 151.694 1.00 49.62  ?  399 ARG A NH2 1 
ATOM   2857  N N   . SER A 1 411 ? 152.749 169.540 145.568 1.00 50.32  ?  400 SER A N   1 
ATOM   2858  C CA  . SER A 1 411 ? 153.523 169.373 144.365 1.00 50.32  ?  400 SER A CA  1 
ATOM   2859  C C   . SER A 1 411 ? 153.078 170.443 143.375 1.00 50.32  ?  400 SER A C   1 
ATOM   2860  O O   . SER A 1 411 ? 153.875 170.922 142.577 1.00 50.32  ?  400 SER A O   1 
ATOM   2861  C CB  . SER A 1 411 ? 153.337 167.970 143.814 1.00 50.32  ?  400 SER A CB  1 
ATOM   2862  O OG  . SER A 1 411 ? 153.773 167.002 144.747 1.00 50.32  ?  400 SER A OG  1 
ATOM   2863  N N   . ALA A 1 412 ? 151.757 170.800 143.426 1.00 51.25  ?  401 ALA A N   1 
ATOM   2864  C CA  . ALA A 1 412 ? 151.297 171.866 142.538 1.00 51.25  ?  401 ALA A CA  1 
ATOM   2865  C C   . ALA A 1 412 ? 151.940 173.216 142.848 1.00 51.25  ?  401 ALA A C   1 
ATOM   2866  O O   . ALA A 1 412 ? 152.336 173.930 141.938 1.00 51.25  ?  401 ALA A O   1 
ATOM   2867  C CB  . ALA A 1 412 ? 149.784 171.980 142.589 1.00 51.25  ?  401 ALA A CB  1 
ATOM   2868  N N   . VAL A 1 413 ? 152.046 173.567 144.123 1.00 54.17  ?  402 VAL A N   1 
ATOM   2869  C CA  . VAL A 1 413 ? 152.676 174.826 144.515 1.00 54.17  ?  402 VAL A CA  1 
ATOM   2870  C C   . VAL A 1 413 ? 154.126 174.917 144.053 1.00 54.17  ?  402 VAL A C   1 
ATOM   2871  O O   . VAL A 1 413 ? 154.530 175.915 143.473 1.00 54.17  ?  402 VAL A O   1 
ATOM   2872  C CB  . VAL A 1 413 ? 152.613 175.032 146.044 1.00 54.17  ?  402 VAL A CB  1 
ATOM   2873  C CG1 . VAL A 1 413 ? 153.562 176.138 146.482 1.00 54.17  ?  402 VAL A CG1 1 
ATOM   2874  C CG2 . VAL A 1 413 ? 151.190 175.317 146.489 1.00 54.17  ?  402 VAL A CG2 1 
ATOM   2875  N N   . GLN A 1 414 ? 154.902 173.868 144.286 1.00 54.76  ?  403 GLN A N   1 
ATOM   2876  C CA  . GLN A 1 414 ? 156.300 173.864 143.878 1.00 54.76  ?  403 GLN A CA  1 
ATOM   2877  C C   . GLN A 1 414 ? 156.439 174.057 142.378 1.00 54.76  ?  403 GLN A C   1 
ATOM   2878  O O   . GLN A 1 414 ? 157.273 174.832 141.928 1.00 54.76  ?  403 GLN A O   1 
ATOM   2879  C CB  . GLN A 1 414 ? 156.970 172.558 144.310 1.00 54.76  ?  403 GLN A CB  1 
ATOM   2880  C CG  . GLN A 1 414 ? 158.426 172.415 143.911 1.00 54.76  ?  403 GLN A CG  1 
ATOM   2881  C CD  . GLN A 1 414 ? 159.098 171.242 144.594 1.00 54.76  ?  403 GLN A CD  1 
ATOM   2882  O OE1 . GLN A 1 414 ? 158.746 170.881 145.714 1.00 54.76  ?  403 GLN A OE1 1 
ATOM   2883  N NE2 . GLN A 1 414 ? 160.076 170.646 143.926 1.00 54.76  ?  403 GLN A NE2 1 
ATOM   2884  N N   . GLU A 1 415 ? 155.619 173.361 141.604 1.00 57.75  ?  404 GLU A N   1 
ATOM   2885  C CA  . GLU A 1 415 ? 155.707 173.446 140.153 1.00 57.75  ?  404 GLU A CA  1 
ATOM   2886  C C   . GLU A 1 415 ? 155.200 174.779 139.617 1.00 57.75  ?  404 GLU A C   1 
ATOM   2887  O O   . GLU A 1 415 ? 155.805 175.356 138.720 1.00 57.75  ?  404 GLU A O   1 
ATOM   2888  C CB  . GLU A 1 415 ? 154.963 172.269 139.512 1.00 57.75  ?  404 GLU A CB  1 
ATOM   2889  C CG  . GLU A 1 415 ? 154.949 172.278 137.995 1.00 57.75  ?  404 GLU A CG  1 
ATOM   2890  C CD  . GLU A 1 415 ? 153.806 173.096 137.436 1.00 57.75  ?  404 GLU A CD  1 
ATOM   2891  O OE1 . GLU A 1 415 ? 152.805 173.288 138.156 1.00 57.75  ?  404 GLU A OE1 1 
ATOM   2892  O OE2 . GLU A 1 415 ? 153.902 173.545 136.280 1.00 57.75  -1 404 GLU A OE2 1 
ATOM   2893  N N   . SER A 1 416 ? 154.106 175.275 140.171 1.00 59.09  ?  405 SER A N   1 
ATOM   2894  C CA  . SER A 1 416 ? 153.540 176.548 139.741 1.00 59.09  ?  405 SER A CA  1 
ATOM   2895  C C   . SER A 1 416 ? 154.402 177.735 140.121 1.00 59.09  ?  405 SER A C   1 
ATOM   2896  O O   . SER A 1 416 ? 154.256 178.811 139.558 1.00 59.09  ?  405 SER A O   1 
ATOM   2897  C CB  . SER A 1 416 ? 152.155 176.721 140.355 1.00 59.09  ?  405 SER A CB  1 
ATOM   2898  O OG  . SER A 1 416 ? 151.635 178.007 140.084 1.00 59.09  ?  405 SER A OG  1 
ATOM   2899  N N   . THR A 1 417 ? 155.298 177.551 141.077 1.00 58.41  ?  406 THR A N   1 
ATOM   2900  C CA  . THR A 1 417 ? 156.148 178.642 141.535 1.00 58.41  ?  406 THR A CA  1 
ATOM   2901  C C   . THR A 1 417 ? 157.501 178.604 140.823 1.00 58.41  ?  406 THR A C   1 
ATOM   2902  O O   . THR A 1 417 ? 158.398 179.378 141.140 1.00 58.41  ?  406 THR A O   1 
ATOM   2903  C CB  . THR A 1 417 ? 156.308 178.610 143.071 1.00 58.41  ?  406 THR A CB  1 
ATOM   2904  O OG1 . THR A 1 417 ? 155.017 178.541 143.682 1.00 58.41  ?  406 THR A OG1 1 
ATOM   2905  C CG2 . THR A 1 417 ? 157.008 179.854 143.565 1.00 58.41  ?  406 THR A CG2 1 
ATOM   2906  N N   . GLY A 1 418 ? 157.654 177.711 139.854 1.00 59.09  ?  407 GLY A N   1 
ATOM   2907  C CA  . GLY A 1 418 ? 158.881 177.677 139.085 1.00 59.09  ?  407 GLY A CA  1 
ATOM   2908  C C   . GLY A 1 418 ? 159.829 176.539 139.351 1.00 59.09  ?  407 GLY A C   1 
ATOM   2909  O O   . GLY A 1 418 ? 161.003 176.620 139.008 1.00 59.09  ?  407 GLY A O   1 
ATOM   2910  N N   . GLY A 1 419 ? 159.334 175.474 139.953 1.00 58.21  ?  408 GLY A N   1 
ATOM   2911  C CA  . GLY A 1 419 ? 160.166 174.323 140.217 1.00 58.21  ?  408 GLY A CA  1 
ATOM   2912  C C   . GLY A 1 419 ? 160.714 173.681 138.967 1.00 58.21  ?  408 GLY A C   1 
ATOM   2913  O O   . GLY A 1 419 ? 159.958 173.318 138.078 1.00 58.21  ?  408 GLY A O   1 
ATOM   2914  N N   . LYS A 1 420 ? 162.029 173.558 138.879 1.00 58.95  ?  409 LYS A N   1 
ATOM   2915  C CA  . LYS A 1 420 ? 162.667 172.903 137.745 1.00 58.95  ?  409 LYS A CA  1 
ATOM   2916  C C   . LYS A 1 420 ? 163.300 171.569 138.100 1.00 58.95  ?  409 LYS A C   1 
ATOM   2917  O O   . LYS A 1 420 ? 163.226 170.628 137.310 1.00 58.95  ?  409 LYS A O   1 
ATOM   2918  C CB  . LYS A 1 420 ? 163.731 173.823 137.144 1.00 58.95  ?  409 LYS A CB  1 
ATOM   2919  C CG  . LYS A 1 420 ? 163.174 175.113 136.569 1.00 58.95  ?  409 LYS A CG  1 
ATOM   2920  C CD  . LYS A 1 420 ? 162.388 174.851 135.301 1.00 58.95  ?  409 LYS A CD  1 
ATOM   2921  C CE  . LYS A 1 420 ? 162.015 176.142 134.597 1.00 58.95  ?  409 LYS A CE  1 
ATOM   2922  N NZ  . LYS A 1 420 ? 160.970 176.899 135.334 1.00 58.95  1  409 LYS A NZ  1 
ATOM   2923  N N   . THR A 1 421 ? 163.925 171.467 139.270 1.00 58.16  ?  410 THR A N   1 
ATOM   2924  C CA  . THR A 1 421 ? 164.526 170.222 139.729 1.00 58.16  ?  410 THR A CA  1 
ATOM   2925  C C   . THR A 1 421 ? 164.093 169.931 141.157 1.00 58.16  ?  410 THR A C   1 
ATOM   2926  O O   . THR A 1 421 ? 163.196 170.595 141.684 1.00 58.16  ?  410 THR A O   1 
ATOM   2927  C CB  . THR A 1 421 ? 166.047 170.293 139.654 1.00 58.16  ?  410 THR A CB  1 
ATOM   2928  O OG1 . THR A 1 421 ? 166.470 171.612 140.013 1.00 58.16  ?  410 THR A OG1 1 
ATOM   2929  C CG2 . THR A 1 421 ? 166.526 169.981 138.254 1.00 58.16  ?  410 THR A CG2 1 
ATOM   2930  N N   . GLN A 1 422 ? 164.715 168.943 141.790 1.00 53.28  ?  411 GLN A N   1 
ATOM   2931  C CA  . GLN A 1 422 ? 164.438 168.685 143.194 1.00 53.28  ?  411 GLN A CA  1 
ATOM   2932  C C   . GLN A 1 422 ? 165.336 169.485 144.125 1.00 53.28  ?  411 GLN A C   1 
ATOM   2933  O O   . GLN A 1 422 ? 165.448 169.133 145.300 1.00 53.28  ?  411 GLN A O   1 
ATOM   2934  C CB  . GLN A 1 422 ? 164.564 167.191 143.501 1.00 53.28  ?  411 GLN A CB  1 
ATOM   2935  C CG  . GLN A 1 422 ? 163.520 166.695 144.480 1.00 53.28  ?  411 GLN A CG  1 
ATOM   2936  C CD  . GLN A 1 422 ? 162.162 166.501 143.846 1.00 53.28  ?  411 GLN A CD  1 
ATOM   2937  O OE1 . GLN A 1 422 ? 162.052 165.956 142.755 1.00 53.28  ?  411 GLN A OE1 1 
ATOM   2938  N NE2 . GLN A 1 422 ? 161.122 166.963 144.519 1.00 53.28  ?  411 GLN A NE2 1 
ATOM   2939  N N   . ILE A 1 423 ? 165.987 170.538 143.628 1.00 53.90  ?  412 ILE A N   1 
ATOM   2940  C CA  . ILE A 1 423 ? 166.632 171.500 144.515 1.00 53.90  ?  412 ILE A CA  1 
ATOM   2941  C C   . ILE A 1 423 ? 165.576 172.339 145.214 1.00 53.90  ?  412 ILE A C   1 
ATOM   2942  O O   . ILE A 1 423 ? 165.799 172.851 146.317 1.00 53.90  ?  412 ILE A O   1 
ATOM   2943  C CB  . ILE A 1 423 ? 167.629 172.368 143.725 1.00 53.90  ?  412 ILE A CB  1 
ATOM   2944  C CG1 . ILE A 1 423 ? 168.662 171.488 143.026 1.00 53.90  ?  412 ILE A CG1 1 
ATOM   2945  C CG2 . ILE A 1 423 ? 168.322 173.367 144.628 1.00 53.90  ?  412 ILE A CG2 1 
ATOM   2946  C CD1 . ILE A 1 423 ? 169.719 170.938 143.942 1.00 53.90  ?  412 ILE A CD1 1 
ATOM   2947  N N   . ALA A 1 424 ? 164.402 172.477 144.597 1.00 53.17  ?  413 ALA A N   1 
ATOM   2948  C CA  . ALA A 1 424 ? 163.279 173.108 145.274 1.00 53.17  ?  413 ALA A CA  1 
ATOM   2949  C C   . ALA A 1 424 ? 162.829 172.279 146.468 1.00 53.17  ?  413 ALA A C   1 
ATOM   2950  O O   . ALA A 1 424 ? 162.466 172.827 147.513 1.00 53.17  ?  413 ALA A O   1 
ATOM   2951  C CB  . ALA A 1 424 ? 162.130 173.317 144.292 1.00 53.17  ?  413 ALA A CB  1 
ATOM   2952  N N   . GLY A 1 425 ? 162.863 170.953 146.341 1.00 51.71  ?  414 GLY A N   1 
ATOM   2953  C CA  . GLY A 1 425 ? 162.569 170.108 147.487 1.00 51.71  ?  414 GLY A CA  1 
ATOM   2954  C C   . GLY A 1 425 ? 163.616 170.226 148.576 1.00 51.71  ?  414 GLY A C   1 
ATOM   2955  O O   . GLY A 1 425 ? 163.291 170.228 149.766 1.00 51.71  ?  414 GLY A O   1 
ATOM   2956  N N   . LEU A 1 426 ? 164.886 170.346 148.186 1.00 50.93  ?  415 LEU A N   1 
ATOM   2957  C CA  . LEU A 1 426 ? 165.949 170.567 149.158 1.00 50.93  ?  415 LEU A CA  1 
ATOM   2958  C C   . LEU A 1 426 ? 165.755 171.883 149.900 1.00 50.93  ?  415 LEU A C   1 
ATOM   2959  O O   . LEU A 1 426 ? 165.967 171.956 151.114 1.00 50.93  ?  415 LEU A O   1 
ATOM   2960  C CB  . LEU A 1 426 ? 167.305 170.538 148.453 1.00 50.93  ?  415 LEU A CB  1 
ATOM   2961  C CG  . LEU A 1 426 ? 168.522 171.093 149.184 1.00 50.93  ?  415 LEU A CG  1 
ATOM   2962  C CD1 . LEU A 1 426 ? 169.005 170.120 150.237 1.00 50.93  ?  415 LEU A CD1 1 
ATOM   2963  C CD2 . LEU A 1 426 ? 169.626 171.397 148.197 1.00 50.93  ?  415 LEU A CD2 1 
ATOM   2964  N N   . ILE A 1 427 ? 165.329 172.932 149.195 1.00 51.54  ?  416 ILE A N   1 
ATOM   2965  C CA  . ILE A 1 427 ? 165.152 174.225 149.850 1.00 51.54  ?  416 ILE A CA  1 
ATOM   2966  C C   . ILE A 1 427 ? 163.901 174.230 150.721 1.00 51.54  ?  416 ILE A C   1 
ATOM   2967  O O   . ILE A 1 427 ? 163.883 174.855 151.791 1.00 51.54  ?  416 ILE A O   1 
ATOM   2968  C CB  . ILE A 1 427 ? 165.138 175.344 148.795 1.00 51.54  ?  416 ILE A CB  1 
ATOM   2969  C CG1 . ILE A 1 427 ? 166.498 175.402 148.103 1.00 51.54  ?  416 ILE A CG1 1 
ATOM   2970  C CG2 . ILE A 1 427 ? 164.809 176.680 149.426 1.00 51.54  ?  416 ILE A CG2 1 
ATOM   2971  C CD1 . ILE A 1 427 ? 166.788 176.698 147.420 1.00 51.54  ?  416 ILE A CD1 1 
ATOM   2972  N N   . GLY A 1 428 ? 162.852 173.519 150.313 1.00 51.38  ?  417 GLY A N   1 
ATOM   2973  C CA  . GLY A 1 428 ? 161.707 173.359 151.192 1.00 51.38  ?  417 GLY A CA  1 
ATOM   2974  C C   . GLY A 1 428 ? 162.055 172.609 152.461 1.00 51.38  ?  417 GLY A C   1 
ATOM   2975  O O   . GLY A 1 428 ? 161.596 172.961 153.552 1.00 51.38  ?  417 GLY A O   1 
ATOM   2976  N N   . ALA A 1 429 ? 162.885 171.570 152.342 1.00 50.99  ?  418 ALA A N   1 
ATOM   2977  C CA  . ALA A 1 429 ? 163.338 170.856 153.530 1.00 50.99  ?  418 ALA A CA  1 
ATOM   2978  C C   . ALA A 1 429 ? 164.237 171.724 154.398 1.00 50.99  ?  418 ALA A C   1 
ATOM   2979  O O   . ALA A 1 429 ? 164.212 171.599 155.624 1.00 50.99  ?  418 ALA A O   1 
ATOM   2980  C CB  . ALA A 1 429 ? 164.060 169.574 153.131 1.00 50.99  ?  418 ALA A CB  1 
ATOM   2981  N N   . ILE A 1 430 ? 165.027 172.610 153.792 1.00 51.73  ?  419 ILE A N   1 
ATOM   2982  C CA  . ILE A 1 430 ? 165.826 173.545 154.580 1.00 51.73  ?  419 ILE A CA  1 
ATOM   2983  C C   . ILE A 1 430 ? 164.925 174.505 155.349 1.00 51.73  ?  419 ILE A C   1 
ATOM   2984  O O   . ILE A 1 430 ? 165.211 174.863 156.497 1.00 51.73  ?  419 ILE A O   1 
ATOM   2985  C CB  . ILE A 1 430 ? 166.817 174.298 153.674 1.00 51.73  ?  419 ILE A CB  1 
ATOM   2986  C CG1 . ILE A 1 430 ? 167.948 173.371 153.232 1.00 51.73  ?  419 ILE A CG1 1 
ATOM   2987  C CG2 . ILE A 1 430 ? 167.390 175.506 154.387 1.00 51.73  ?  419 ILE A CG2 1 
ATOM   2988  C CD1 . ILE A 1 430 ? 168.831 173.974 152.171 1.00 51.73  ?  419 ILE A CD1 1 
ATOM   2989  N N   . ILE A 1 431 ? 163.862 174.975 154.829 1.00 53.32  ?  420 ILE A N   1 
ATOM   2990  C CA  . ILE A 1 431 ? 162.958 175.848 155.569 1.00 53.32  ?  420 ILE A CA  1 
ATOM   2991  C C   . ILE A 1 431 ? 162.241 175.080 156.673 1.00 53.32  ?  420 ILE A C   1 
ATOM   2992  O O   . ILE A 1 431 ? 162.004 175.620 157.749 1.00 53.32  ?  420 ILE A O   1 
ATOM   2993  C CB  . ILE A 1 431 ? 161.933 176.516 154.633 1.00 53.32  ?  420 ILE A CB  1 
ATOM   2994  C CG1 . ILE A 1 431 ? 162.641 177.465 153.670 1.00 53.32  ?  420 ILE A CG1 1 
ATOM   2995  C CG2 . ILE A 1 431 ? 160.874 177.259 155.430 1.00 53.32  ?  420 ILE A CG2 1 
ATOM   2996  C CD1 . ILE A 1 431 ? 161.700 178.147 152.708 1.00 53.32  ?  420 ILE A CD1 1 
ATOM   2997  N N   . VAL A 1 432 ? 161.846 173.805 156.374 1.00 51.80  ?  421 VAL A N   1 
ATOM   2998  C CA  . VAL A 1 432 ? 161.274 173.002 157.454 1.00 51.80  ?  421 VAL A CA  1 
ATOM   2999  C C   . VAL A 1 432 ? 162.291 172.811 158.576 1.00 51.80  ?  421 VAL A C   1 
ATOM   3000  O O   . VAL A 1 432 ? 161.940 172.830 159.762 1.00 51.80  ?  421 VAL A O   1 
ATOM   3001  C CB  . VAL A 1 432 ? 160.771 171.655 156.906 1.00 51.80  ?  421 VAL A CB  1 
ATOM   3002  C CG1 . VAL A 1 432 ? 160.273 170.781 158.032 1.00 51.80  ?  421 VAL A CG1 1 
ATOM   3003  C CG2 . VAL A 1 432 ? 159.673 171.881 155.893 1.00 51.80  ?  421 VAL A CG2 1 
ATOM   3004  N N   . LEU A 1 433 ? 163.564 172.632 158.224 1.00 52.12  ?  422 LEU A N   1 
ATOM   3005  C CA  . LEU A 1 433 ? 164.622 172.531 159.225 1.00 52.12  ?  422 LEU A CA  1 
ATOM   3006  C C   . LEU A 1 433 ? 164.744 173.816 160.030 1.00 52.12  ?  422 LEU A C   1 
ATOM   3007  O O   . LEU A 1 433 ? 164.907 173.785 161.253 1.00 52.12  ?  422 LEU A O   1 
ATOM   3008  C CB  . LEU A 1 433 ? 165.949 172.206 158.540 1.00 52.12  ?  422 LEU A CB  1 
ATOM   3009  C CG  . LEU A 1 433 ? 167.210 172.114 159.395 1.00 52.12  ?  422 LEU A CG  1 
ATOM   3010  C CD1 . LEU A 1 433 ? 167.515 170.681 159.761 1.00 52.12  ?  422 LEU A CD1 1 
ATOM   3011  C CD2 . LEU A 1 433 ? 168.375 172.729 158.658 1.00 52.12  ?  422 LEU A CD2 1 
ATOM   3012  N N   . ILE A 1 434 ? 164.690 174.962 159.350 1.00 54.10  ?  423 ILE A N   1 
ATOM   3013  C CA  . ILE A 1 434 ? 164.757 176.248 160.039 1.00 54.10  ?  423 ILE A CA  1 
ATOM   3014  C C   . ILE A 1 434 ? 163.607 176.375 161.026 1.00 54.10  ?  423 ILE A C   1 
ATOM   3015  O O   . ILE A 1 434 ? 163.787 176.822 162.165 1.00 54.10  ?  423 ILE A O   1 
ATOM   3016  C CB  . ILE A 1 434 ? 164.754 177.402 159.020 1.00 54.10  ?  423 ILE A CB  1 
ATOM   3017  C CG1 . ILE A 1 434 ? 166.117 177.518 158.342 1.00 54.10  ?  423 ILE A CG1 1 
ATOM   3018  C CG2 . ILE A 1 434 ? 164.372 178.710 159.691 1.00 54.10  ?  423 ILE A CG2 1 
ATOM   3019  C CD1 . ILE A 1 434 ? 166.124 178.459 157.164 1.00 54.10  ?  423 ILE A CD1 1 
ATOM   3020  N N   . VAL A 1 435 ? 162.405 175.975 160.607 1.00 54.92  ?  424 VAL A N   1 
ATOM   3021  C CA  . VAL A 1 435 ? 161.254 176.041 161.503 1.00 54.92  ?  424 VAL A CA  1 
ATOM   3022  C C   . VAL A 1 435 ? 161.441 175.116 162.696 1.00 54.92  ?  424 VAL A C   1 
ATOM   3023  O O   . VAL A 1 435 ? 161.145 175.493 163.833 1.00 54.92  ?  424 VAL A O   1 
ATOM   3024  C CB  . VAL A 1 435 ? 159.956 175.724 160.736 1.00 54.92  ?  424 VAL A CB  1 
ATOM   3025  C CG1 . VAL A 1 435 ? 158.868 175.281 161.686 1.00 54.92  ?  424 VAL A CG1 1 
ATOM   3026  C CG2 . VAL A 1 435 ? 159.505 176.940 159.955 1.00 54.92  ?  424 VAL A CG2 1 
ATOM   3027  N N   . VAL A 1 436 ? 161.944 173.902 162.466 1.00 54.13  ?  425 VAL A N   1 
ATOM   3028  C CA  . VAL A 1 436 ? 162.145 172.956 163.561 1.00 54.13  ?  425 VAL A CA  1 
ATOM   3029  C C   . VAL A 1 436 ? 163.143 173.505 164.574 1.00 54.13  ?  425 VAL A C   1 
ATOM   3030  O O   . VAL A 1 436 ? 162.886 173.503 165.782 1.00 54.13  ?  425 VAL A O   1 
ATOM   3031  C CB  . VAL A 1 436 ? 162.602 171.590 163.015 1.00 54.13  ?  425 VAL A CB  1 
ATOM   3032  C CG1 . VAL A 1 436 ? 163.168 170.746 164.126 1.00 54.13  ?  425 VAL A CG1 1 
ATOM   3033  C CG2 . VAL A 1 436 ? 161.455 170.875 162.355 1.00 54.13  ?  425 VAL A CG2 1 
ATOM   3034  N N   . LEU A 1 437 ? 164.288 173.993 164.098 1.00 56.28  ?  426 LEU A N   1 
ATOM   3035  C CA  . LEU A 1 437 ? 165.382 174.332 165.001 1.00 56.28  ?  426 LEU A CA  1 
ATOM   3036  C C   . LEU A 1 437 ? 165.291 175.747 165.557 1.00 56.28  ?  426 LEU A C   1 
ATOM   3037  O O   . LEU A 1 437 ? 165.675 175.971 166.710 1.00 56.28  ?  426 LEU A O   1 
ATOM   3038  C CB  . LEU A 1 437 ? 166.725 174.160 164.289 1.00 56.28  ?  426 LEU A CB  1 
ATOM   3039  C CG  . LEU A 1 437 ? 167.098 172.770 163.780 1.00 56.28  ?  426 LEU A CG  1 
ATOM   3040  C CD1 . LEU A 1 437 ? 168.372 172.846 162.968 1.00 56.28  ?  426 LEU A CD1 1 
ATOM   3041  C CD2 . LEU A 1 437 ? 167.263 171.805 164.931 1.00 56.28  ?  426 LEU A CD2 1 
ATOM   3042  N N   . ALA A 1 438 ? 164.807 176.710 164.779 1.00 57.02  ?  427 ALA A N   1 
ATOM   3043  C CA  . ALA A 1 438 ? 164.954 178.111 165.154 1.00 57.02  ?  427 ALA A CA  1 
ATOM   3044  C C   . ALA A 1 438 ? 163.645 178.834 165.426 1.00 57.02  ?  427 ALA A C   1 
ATOM   3045  O O   . ALA A 1 438 ? 163.498 179.436 166.492 1.00 57.02  ?  427 ALA A O   1 
ATOM   3046  C CB  . ALA A 1 438 ? 165.720 178.868 164.060 1.00 57.02  ?  427 ALA A CB  1 
ATOM   3047  N N   . ILE A 1 439 ? 162.687 178.802 164.500 1.00 57.64  ?  428 ILE A N   1 
ATOM   3048  C CA  . ILE A 1 439 ? 161.516 179.668 164.606 1.00 57.64  ?  428 ILE A CA  1 
ATOM   3049  C C   . ILE A 1 439 ? 160.234 178.858 164.755 1.00 57.64  ?  428 ILE A C   1 
ATOM   3050  O O   . ILE A 1 439 ? 159.172 179.269 164.276 1.00 57.64  ?  428 ILE A O   1 
ATOM   3051  C CB  . ILE A 1 439 ? 161.421 180.617 163.396 1.00 57.64  ?  428 ILE A CB  1 
ATOM   3052  C CG1 . ILE A 1 439 ? 161.348 179.828 162.088 1.00 57.64  ?  428 ILE A CG1 1 
ATOM   3053  C CG2 . ILE A 1 439 ? 162.597 181.575 163.379 1.00 57.64  ?  428 ILE A CG2 1 
ATOM   3054  C CD1 . ILE A 1 439 ? 160.696 180.588 160.959 1.00 57.64  ?  428 ILE A CD1 1 
ATOM   3055  N N   . GLY A 1 440 ? 160.316 177.710 165.421 1.00 59.32  ?  429 GLY A N   1 
ATOM   3056  C CA  . GLY A 1 440 ? 159.103 176.977 165.736 1.00 59.32  ?  429 GLY A CA  1 
ATOM   3057  C C   . GLY A 1 440 ? 158.223 177.644 166.771 1.00 59.32  ?  429 GLY A C   1 
ATOM   3058  O O   . GLY A 1 440 ? 156.999 177.493 166.711 1.00 59.32  ?  429 GLY A O   1 
ATOM   3059  N N   . PHE A 1 441 ? 158.818 178.397 167.701 1.00 61.26  ?  430 PHE A N   1 
ATOM   3060  C CA  . PHE A 1 441 ? 158.050 179.070 168.741 1.00 61.26  ?  430 PHE A CA  1 
ATOM   3061  C C   . PHE A 1 441 ? 157.066 180.088 168.182 1.00 61.26  ?  430 PHE A C   1 
ATOM   3062  O O   . PHE A 1 441 ? 156.136 180.481 168.890 1.00 61.26  ?  430 PHE A O   1 
ATOM   3063  C CB  . PHE A 1 441 ? 158.995 179.756 169.726 1.00 61.26  ?  430 PHE A CB  1 
ATOM   3064  C CG  . PHE A 1 441 ? 159.654 180.985 169.177 1.00 61.26  ?  430 PHE A CG  1 
ATOM   3065  C CD1 . PHE A 1 441 ? 160.753 180.882 168.346 1.00 61.26  ?  430 PHE A CD1 1 
ATOM   3066  C CD2 . PHE A 1 441 ? 159.181 182.243 169.495 1.00 61.26  ?  430 PHE A CD2 1 
ATOM   3067  C CE1 . PHE A 1 441 ? 161.361 182.007 167.840 1.00 61.26  ?  430 PHE A CE1 1 
ATOM   3068  C CE2 . PHE A 1 441 ? 159.788 183.371 168.992 1.00 61.26  ?  430 PHE A CE2 1 
ATOM   3069  C CZ  . PHE A 1 441 ? 160.879 183.253 168.164 1.00 61.26  ?  430 PHE A CZ  1 
ATOM   3070  N N   . LEU A 1 442 ? 157.252 180.533 166.938 1.00 60.03  ?  431 LEU A N   1 
ATOM   3071  C CA  . LEU A 1 442 ? 156.280 181.436 166.336 1.00 60.03  ?  431 LEU A CA  1 
ATOM   3072  C C   . LEU A 1 442 ? 154.954 180.737 166.079 1.00 60.03  ?  431 LEU A C   1 
ATOM   3073  O O   . LEU A 1 442 ? 153.901 181.380 166.123 1.00 60.03  ?  431 LEU A O   1 
ATOM   3074  C CB  . LEU A 1 442 ? 156.825 182.012 165.033 1.00 60.03  ?  431 LEU A CB  1 
ATOM   3075  C CG  . LEU A 1 442 ? 158.001 182.976 165.138 1.00 60.03  ?  431 LEU A CG  1 
ATOM   3076  C CD1 . LEU A 1 442 ? 158.344 183.515 163.767 1.00 60.03  ?  431 LEU A CD1 1 
ATOM   3077  C CD2 . LEU A 1 442 ? 157.680 184.107 166.093 1.00 60.03  ?  431 LEU A CD2 1 
ATOM   3078  N N   . LEU A 1 443 ? 154.979 179.437 165.816 1.00 60.40  ?  432 LEU A N   1 
ATOM   3079  C CA  . LEU A 1 443 ? 153.763 178.688 165.538 1.00 60.40  ?  432 LEU A CA  1 
ATOM   3080  C C   . LEU A 1 443 ? 153.061 178.224 166.803 1.00 60.40  ?  432 LEU A C   1 
ATOM   3081  O O   . LEU A 1 443 ? 152.236 177.311 166.739 1.00 60.40  ?  432 LEU A O   1 
ATOM   3082  C CB  . LEU A 1 443 ? 154.078 177.488 164.644 1.00 60.40  ?  432 LEU A CB  1 
ATOM   3083  C CG  . LEU A 1 443 ? 154.649 177.813 163.265 1.00 60.40  ?  432 LEU A CG  1 
ATOM   3084  C CD1 . LEU A 1 443 ? 155.186 176.565 162.603 1.00 60.40  ?  432 LEU A CD1 1 
ATOM   3085  C CD2 . LEU A 1 443 ? 153.597 178.468 162.392 1.00 60.40  ?  432 LEU A CD2 1 
ATOM   3086  N N   . ALA A 1 444 ? 153.371 178.826 167.946 1.00 62.97  ?  433 ALA A N   1 
ATOM   3087  C CA  . ALA A 1 444 ? 152.797 178.427 169.224 1.00 62.97  ?  433 ALA A CA  1 
ATOM   3088  C C   . ALA A 1 444 ? 151.364 178.925 169.400 1.00 62.97  ?  433 ALA A C   1 
ATOM   3089  O O   . ALA A 1 444 ? 150.504 178.136 169.807 1.00 62.97  ?  433 ALA A O   1 
ATOM   3090  C CB  . ALA A 1 444 ? 153.678 178.909 170.381 1.00 62.97  ?  433 ALA A CB  1 
ATOM   3091  N N   . PRO A 1 445 ? 151.045 180.193 169.128 1.00 64.07  ?  434 PRO A N   1 
ATOM   3092  C CA  . PRO A 1 445 ? 149.668 180.657 169.313 1.00 64.07  ?  434 PRO A CA  1 
ATOM   3093  C C   . PRO A 1 445 ? 148.724 180.326 168.168 1.00 64.07  ?  434 PRO A C   1 
ATOM   3094  O O   . PRO A 1 445 ? 147.582 180.791 168.184 1.00 64.07  ?  434 PRO A O   1 
ATOM   3095  C CB  . PRO A 1 445 ? 149.849 182.175 169.440 1.00 64.07  ?  434 PRO A CB  1 
ATOM   3096  C CG  . PRO A 1 445 ? 150.968 182.457 168.554 1.00 64.07  ?  434 PRO A CG  1 
ATOM   3097  C CD  . PRO A 1 445 ? 151.922 181.316 168.741 1.00 64.07  ?  434 PRO A CD  1 
ATOM   3098  N N   . LEU A 1 446 ? 149.152 179.542 167.187 1.00 62.21  ?  435 LEU A N   1 
ATOM   3099  C CA  . LEU A 1 446 ? 148.306 179.215 166.048 1.00 62.21  ?  435 LEU A CA  1 
ATOM   3100  C C   . LEU A 1 446 ? 147.274 178.162 166.423 1.00 62.21  ?  435 LEU A C   1 
ATOM   3101  O O   . LEU A 1 446 ? 147.614 177.103 166.953 1.00 62.21  ?  435 LEU A O   1 
ATOM   3102  C CB  . LEU A 1 446 ? 149.158 178.715 164.884 1.00 62.21  ?  435 LEU A CB  1 
ATOM   3103  C CG  . LEU A 1 446 ? 148.395 178.372 163.610 1.00 62.21  ?  435 LEU A CG  1 
ATOM   3104  C CD1 . LEU A 1 446 ? 147.934 179.638 162.923 1.00 62.21  ?  435 LEU A CD1 1 
ATOM   3105  C CD2 . LEU A 1 446 ? 149.247 177.529 162.689 1.00 62.21  ?  435 LEU A CD2 1 
ATOM   3106  N N   . GLN A 1 447 ? 146.009 178.451 166.126 1.00 60.73  ?  436 GLN A N   1 
ATOM   3107  C CA  . GLN A 1 447 ? 144.938 177.519 166.440 1.00 60.73  ?  436 GLN A CA  1 
ATOM   3108  C C   . GLN A 1 447 ? 144.972 176.319 165.500 1.00 60.73  ?  436 GLN A C   1 
ATOM   3109  O O   . GLN A 1 447 ? 145.470 176.385 164.378 1.00 60.73  ?  436 GLN A O   1 
ATOM   3110  C CB  . GLN A 1 447 ? 143.571 178.192 166.341 1.00 60.73  ?  436 GLN A CB  1 
ATOM   3111  C CG  . GLN A 1 447 ? 143.510 179.613 166.850 1.00 60.73  ?  436 GLN A CG  1 
ATOM   3112  C CD  . GLN A 1 447 ? 142.148 180.235 166.623 1.00 60.73  ?  436 GLN A CD  1 
ATOM   3113  O OE1 . GLN A 1 447 ? 142.024 181.451 166.502 1.00 60.73  ?  436 GLN A OE1 1 
ATOM   3114  N NE2 . GLN A 1 447 ? 141.118 179.403 166.575 1.00 60.73  ?  436 GLN A NE2 1 
ATOM   3115  N N   . LYS A 1 448 ? 144.418 175.207 165.979 1.00 56.14  ?  437 LYS A N   1 
ATOM   3116  C CA  . LYS A 1 448 ? 144.303 174.013 165.157 1.00 56.14  ?  437 LYS A CA  1 
ATOM   3117  C C   . LYS A 1 448 ? 143.120 174.083 164.203 1.00 56.14  ?  437 LYS A C   1 
ATOM   3118  O O   . LYS A 1 448 ? 143.092 173.348 163.207 1.00 56.14  ?  437 LYS A O   1 
ATOM   3119  C CB  . LYS A 1 448 ? 144.181 172.783 166.049 1.00 56.14  ?  437 LYS A CB  1 
ATOM   3120  C CG  . LYS A 1 448 ? 145.256 172.702 167.110 1.00 56.14  ?  437 LYS A CG  1 
ATOM   3121  C CD  . LYS A 1 448 ? 145.154 171.417 167.890 1.00 56.14  ?  437 LYS A CD  1 
ATOM   3122  C CE  . LYS A 1 448 ? 146.319 171.270 168.840 1.00 56.14  ?  437 LYS A CE  1 
ATOM   3123  N NZ  . LYS A 1 448 ? 146.270 169.986 169.584 1.00 56.14  1  437 LYS A NZ  1 
ATOM   3124  N N   . SER A 1 449 ? 142.152 174.956 164.482 1.00 56.77  ?  438 SER A N   1 
ATOM   3125  C CA  . SER A 1 449 ? 141.038 175.143 163.562 1.00 56.77  ?  438 SER A CA  1 
ATOM   3126  C C   . SER A 1 449 ? 141.512 175.745 162.249 1.00 56.77  ?  438 SER A C   1 
ATOM   3127  O O   . SER A 1 449 ? 140.970 175.429 161.187 1.00 56.77  ?  438 SER A O   1 
ATOM   3128  C CB  . SER A 1 449 ? 139.974 176.022 164.209 1.00 56.77  ?  438 SER A CB  1 
ATOM   3129  O OG  . SER A 1 449 ? 140.497 177.293 164.534 1.00 56.77  ?  438 SER A OG  1 
ATOM   3130  N N   . VAL A 1 450 ? 142.533 176.601 162.297 1.00 57.88  ?  439 VAL A N   1 
ATOM   3131  C CA  . VAL A 1 450 ? 143.089 177.174 161.076 1.00 57.88  ?  439 VAL A CA  1 
ATOM   3132  C C   . VAL A 1 450 ? 143.745 176.092 160.225 1.00 57.88  ?  439 VAL A C   1 
ATOM   3133  O O   . VAL A 1 450 ? 143.602 176.073 158.997 1.00 57.88  ?  439 VAL A O   1 
ATOM   3134  C CB  . VAL A 1 450 ? 144.076 178.301 161.423 1.00 57.88  ?  439 VAL A CB  1 
ATOM   3135  C CG1 . VAL A 1 450 ? 144.690 178.877 160.167 1.00 57.88  ?  439 VAL A CG1 1 
ATOM   3136  C CG2 . VAL A 1 450 ? 143.371 179.380 162.220 1.00 57.88  ?  439 VAL A CG2 1 
ATOM   3137  N N   . LEU A 1 451 ? 144.462 175.168 160.862 1.00 54.59  ?  440 LEU A N   1 
ATOM   3138  C CA  . LEU A 1 451 ? 145.068 174.063 160.129 1.00 54.59  ?  440 LEU A CA  1 
ATOM   3139  C C   . LEU A 1 451 ? 144.003 173.162 159.513 1.00 54.59  ?  440 LEU A C   1 
ATOM   3140  O O   . LEU A 1 451 ? 144.122 172.737 158.354 1.00 54.59  ?  440 LEU A O   1 
ATOM   3141  C CB  . LEU A 1 451 ? 145.988 173.274 161.059 1.00 54.59  ?  440 LEU A CB  1 
ATOM   3142  C CG  . LEU A 1 451 ? 147.059 174.088 161.790 1.00 54.59  ?  440 LEU A CG  1 
ATOM   3143  C CD1 . LEU A 1 451 ? 147.693 173.276 162.900 1.00 54.59  ?  440 LEU A CD1 1 
ATOM   3144  C CD2 . LEU A 1 451 ? 148.119 174.575 160.824 1.00 54.59  ?  440 LEU A CD2 1 
ATOM   3145  N N   . ALA A 1 452 ? 142.946 172.866 160.272 1.00 56.08  ?  441 ALA A N   1 
ATOM   3146  C CA  . ALA A 1 452 ? 141.835 172.099 159.717 1.00 56.08  ?  441 ALA A CA  1 
ATOM   3147  C C   . ALA A 1 452 ? 141.202 172.812 158.526 1.00 56.08  ?  441 ALA A C   1 
ATOM   3148  O O   . ALA A 1 452 ? 140.855 172.179 157.520 1.00 56.08  ?  441 ALA A O   1 
ATOM   3149  C CB  . ALA A 1 452 ? 140.795 171.837 160.803 1.00 56.08  ?  441 ALA A CB  1 
ATOM   3150  N N   . ALA A 1 453 ? 141.046 174.132 158.621 1.00 57.67  ?  442 ALA A N   1 
ATOM   3151  C CA  . ALA A 1 453 ? 140.449 174.894 157.532 1.00 57.67  ?  442 ALA A CA  1 
ATOM   3152  C C   . ALA A 1 453 ? 141.320 174.858 156.285 1.00 57.67  ?  442 ALA A C   1 
ATOM   3153  O O   . ALA A 1 453 ? 140.805 174.763 155.164 1.00 57.67  ?  442 ALA A O   1 
ATOM   3154  C CB  . ALA A 1 453 ? 140.207 176.333 157.978 1.00 57.67  ?  442 ALA A CB  1 
ATOM   3155  N N   . LEU A 1 454 ? 142.640 174.940 156.455 1.00 57.95  ?  443 LEU A N   1 
ATOM   3156  C CA  . LEU A 1 454 ? 143.535 174.793 155.311 1.00 57.95  ?  443 LEU A CA  1 
ATOM   3157  C C   . LEU A 1 454 ? 143.375 173.421 154.665 1.00 57.95  ?  443 LEU A C   1 
ATOM   3158  O O   . LEU A 1 454 ? 143.319 173.301 153.431 1.00 57.95  ?  443 LEU A O   1 
ATOM   3159  C CB  . LEU A 1 454 ? 144.983 175.021 155.742 1.00 57.95  ?  443 LEU A CB  1 
ATOM   3160  C CG  . LEU A 1 454 ? 145.322 176.362 156.391 1.00 57.95  ?  443 LEU A CG  1 
ATOM   3161  C CD1 . LEU A 1 454 ? 146.763 176.377 156.858 1.00 57.95  ?  443 LEU A CD1 1 
ATOM   3162  C CD2 . LEU A 1 454 ? 145.052 177.509 155.443 1.00 57.95  ?  443 LEU A CD2 1 
ATOM   3163  N N   . ALA A 1 455 ? 143.293 172.371 155.487 1.00 57.06  ?  444 ALA A N   1 
ATOM   3164  C CA  . ALA A 1 455 ? 143.100 171.028 154.945 1.00 57.06  ?  444 ALA A CA  1 
ATOM   3165  C C   . ALA A 1 455 ? 141.810 170.931 154.136 1.00 57.06  ?  444 ALA A C   1 
ATOM   3166  O O   . ALA A 1 455 ? 141.787 170.317 153.064 1.00 57.06  ?  444 ALA A O   1 
ATOM   3167  C CB  . ALA A 1 455 ? 143.103 170.004 156.075 1.00 57.06  ?  444 ALA A CB  1 
ATOM   3168  N N   . LEU A 1 456 ? 140.728 171.542 154.622 1.00 57.42  ?  445 LEU A N   1 
ATOM   3169  C CA  . LEU A 1 456 ? 139.461 171.482 153.891 1.00 57.42  ?  445 LEU A CA  1 
ATOM   3170  C C   . LEU A 1 456 ? 139.529 172.272 152.584 1.00 57.42  ?  445 LEU A C   1 
ATOM   3171  O O   . LEU A 1 456 ? 138.991 171.838 151.545 1.00 57.42  ?  445 LEU A O   1 
ATOM   3172  C CB  . LEU A 1 456 ? 138.327 172.000 154.772 1.00 57.42  ?  445 LEU A CB  1 
ATOM   3173  C CG  . LEU A 1 456 ? 138.157 171.285 156.111 1.00 57.42  ?  445 LEU A CG  1 
ATOM   3174  C CD1 . LEU A 1 456 ? 136.953 171.813 156.862 1.00 57.42  ?  445 LEU A CD1 1 
ATOM   3175  C CD2 . LEU A 1 456 ? 138.044 169.795 155.891 1.00 57.42  ?  445 LEU A CD2 1 
ATOM   3176  N N   . GLY A 1 457 ? 140.156 173.447 152.626 1.00 59.80  ?  446 GLY A N   1 
ATOM   3177  C CA  . GLY A 1 457 ? 140.368 174.204 151.409 1.00 59.80  ?  446 GLY A CA  1 
ATOM   3178  C C   . GLY A 1 457 ? 141.107 173.412 150.355 1.00 59.80  ?  446 GLY A C   1 
ATOM   3179  O O   . GLY A 1 457 ? 140.817 173.534 149.163 1.00 59.80  ?  446 GLY A O   1 
ATOM   3180  N N   . ASN A 1 458 ? 142.066 172.588 150.773 1.00 59.43  ?  447 ASN A N   1 
ATOM   3181  C CA  . ASN A 1 458 ? 142.720 171.694 149.823 1.00 59.43  ?  447 ASN A CA  1 
ATOM   3182  C C   . ASN A 1 458 ? 141.847 170.508 149.434 1.00 59.43  ?  447 ASN A C   1 
ATOM   3183  O O   . ASN A 1 458 ? 142.040 169.937 148.357 1.00 59.43  ?  447 ASN A O   1 
ATOM   3184  C CB  . ASN A 1 458 ? 144.040 171.188 150.397 1.00 59.43  ?  447 ASN A CB  1 
ATOM   3185  C CG  . ASN A 1 458 ? 145.148 172.199 150.267 1.00 59.43  ?  447 ASN A CG  1 
ATOM   3186  O OD1 . ASN A 1 458 ? 145.265 172.878 149.248 1.00 59.43  ?  447 ASN A OD1 1 
ATOM   3187  N ND2 . ASN A 1 458 ? 145.974 172.309 151.298 1.00 59.43  ?  447 ASN A ND2 1 
ATOM   3188  N N   . LEU A 1 459 ? 140.903 170.120 150.292 1.00 56.03  ?  448 LEU A N   1 
ATOM   3189  C CA  . LEU A 1 459 ? 140.016 168.990 150.033 1.00 56.03  ?  448 LEU A CA  1 
ATOM   3190  C C   . LEU A 1 459 ? 139.001 169.261 148.936 1.00 56.03  ?  448 LEU A C   1 
ATOM   3191  O O   . LEU A 1 459 ? 138.516 168.303 148.315 1.00 56.03  ?  448 LEU A O   1 
ATOM   3192  C CB  . LEU A 1 459 ? 139.267 168.633 151.310 1.00 56.03  ?  448 LEU A CB  1 
ATOM   3193  C CG  . LEU A 1 459 ? 139.326 167.193 151.777 1.00 56.03  ?  448 LEU A CG  1 
ATOM   3194  C CD1 . LEU A 1 459 ? 140.747 166.680 151.707 1.00 56.03  ?  448 LEU A CD1 1 
ATOM   3195  C CD2 . LEU A 1 459 ? 138.808 167.162 153.183 1.00 56.03  ?  448 LEU A CD2 1 
ATOM   3196  N N   . LYS A 1 460 ? 138.571 170.411 148.663 1.00 58.85  ?  449 LYS A N   1 
ATOM   3197  C CA  . LYS A 1 460 ? 137.511 170.684 147.679 1.00 58.85  ?  449 LYS A CA  1 
ATOM   3198  C C   . LYS A 1 460 ? 137.782 170.123 146.311 1.00 58.85  ?  449 LYS A C   1 
ATOM   3199  O O   . LYS A 1 460 ? 136.864 169.787 145.565 1.00 58.85  ?  449 LYS A O   1 
ATOM   3200  C CB  . LYS A 1 460 ? 137.327 172.196 147.555 1.00 58.85  ?  449 LYS A CB  1 
ATOM   3201  C CG  . LYS A 1 460 ? 136.491 172.653 146.371 1.00 58.85  ?  449 LYS A CG  1 
ATOM   3202  C CD  . LYS A 1 460 ? 137.366 173.053 145.195 1.00 58.85  ?  449 LYS A CD  1 
ATOM   3203  C CE  . LYS A 1 460 ? 136.529 173.564 144.036 1.00 58.85  ?  449 LYS A CE  1 
ATOM   3204  N NZ  . LYS A 1 460 ? 137.376 174.013 142.896 1.00 58.85  1  449 LYS A NZ  1 
ATOM   3205  N N   . GLY A 1 461 ? 139.111 170.105 145.957 1.00 56.81  ?  450 GLY A N   1 
ATOM   3206  C CA  . GLY A 1 461 ? 139.431 169.551 144.651 1.00 56.81  ?  450 GLY A CA  1 
ATOM   3207  C C   . GLY A 1 461 ? 139.069 168.092 144.467 1.00 56.81  ?  450 GLY A C   1 
ATOM   3208  O O   . GLY A 1 461 ? 138.557 167.704 143.415 1.00 56.81  ?  450 GLY A O   1 
ATOM   3209  N N   . MET A 1 462 ? 139.353 167.266 145.478 1.00 55.22  ?  451 MET A N   1 
ATOM   3210  C CA  . MET A 1 462 ? 138.930 165.872 145.430 1.00 55.22  ?  451 MET A CA  1 
ATOM   3211  C C   . MET A 1 462 ? 137.437 165.735 145.671 1.00 55.22  ?  451 MET A C   1 
ATOM   3212  O O   . MET A 1 462 ? 136.813 164.795 145.173 1.00 55.22  ?  451 MET A O   1 
ATOM   3213  C CB  . MET A 1 462 ? 139.693 165.045 146.462 1.00 55.22  ?  451 MET A CB  1 
ATOM   3214  C CG  . MET A 1 462 ? 141.073 164.604 146.037 1.00 55.22  ?  451 MET A CG  1 
ATOM   3215  S SD  . MET A 1 462 ? 141.838 163.540 147.274 1.00 55.22  ?  451 MET A SD  1 
ATOM   3216  C CE  . MET A 1 462 ? 141.986 164.673 148.652 1.00 55.22  ?  451 MET A CE  1 
ATOM   3217  N N   . LEU A 1 463 ? 136.847 166.649 146.446 1.00 54.11  ?  452 LEU A N   1 
ATOM   3218  C CA  . LEU A 1 463 ? 135.404 166.571 146.661 1.00 54.11  ?  452 LEU A CA  1 
ATOM   3219  C C   . LEU A 1 463 ? 134.634 166.850 145.379 1.00 54.11  ?  452 LEU A C   1 
ATOM   3220  O O   . LEU A 1 463 ? 133.524 166.342 145.203 1.00 54.11  ?  452 LEU A O   1 
ATOM   3221  C CB  . LEU A 1 463 ? 134.974 167.543 147.756 1.00 54.11  ?  452 LEU A CB  1 
ATOM   3222  C CG  . LEU A 1 463 ? 135.082 167.023 149.187 1.00 54.11  ?  452 LEU A CG  1 
ATOM   3223  C CD1 . LEU A 1 463 ? 134.506 168.036 150.150 1.00 54.11  ?  452 LEU A CD1 1 
ATOM   3224  C CD2 . LEU A 1 463 ? 134.377 165.691 149.325 1.00 54.11  ?  452 LEU A CD2 1 
ATOM   3225  N N   . MET A 1 464 ? 135.201 167.649 144.480 1.00 57.45  ?  453 MET A N   1 
ATOM   3226  C CA  . MET A 1 464 ? 134.513 167.973 143.233 1.00 57.45  ?  453 MET A CA  1 
ATOM   3227  C C   . MET A 1 464 ? 134.447 166.809 142.246 1.00 57.45  ?  453 MET A C   1 
ATOM   3228  O O   . MET A 1 464 ? 133.934 167.001 141.139 1.00 57.45  ?  453 MET A O   1 
ATOM   3229  C CB  . MET A 1 464 ? 135.188 169.168 142.561 1.00 57.45  ?  453 MET A CB  1 
ATOM   3230  C CG  . MET A 1 464 ? 134.230 170.135 141.901 1.00 57.45  ?  453 MET A CG  1 
ATOM   3231  S SD  . MET A 1 464 ? 135.054 171.635 141.349 1.00 57.45  ?  453 MET A SD  1 
ATOM   3232  C CE  . MET A 1 464 ? 136.494 170.946 140.538 1.00 57.45  ?  453 MET A CE  1 
ATOM   3233  N N   . GLN A 1 465 ? 134.937 165.621 142.600 1.00 50.05  ?  454 GLN A N   1 
ATOM   3234  C CA  . GLN A 1 465 ? 134.922 164.466 141.707 1.00 50.05  ?  454 GLN A CA  1 
ATOM   3235  C C   . GLN A 1 465 ? 133.603 163.710 141.727 1.00 50.05  ?  454 GLN A C   1 
ATOM   3236  O O   . GLN A 1 465 ? 133.504 162.662 141.082 1.00 50.05  ?  454 GLN A O   1 
ATOM   3237  C CB  . GLN A 1 465 ? 136.057 163.505 142.062 1.00 50.05  ?  454 GLN A CB  1 
ATOM   3238  C CG  . GLN A 1 465 ? 137.429 163.985 141.668 1.00 50.05  ?  454 GLN A CG  1 
ATOM   3239  C CD  . GLN A 1 465 ? 138.511 162.990 142.018 1.00 50.05  ?  454 GLN A CD  1 
ATOM   3240  O OE1 . GLN A 1 465 ? 139.403 162.718 141.218 1.00 50.05  ?  454 GLN A OE1 1 
ATOM   3241  N NE2 . GLN A 1 465 ? 138.440 162.440 143.218 1.00 50.05  ?  454 GLN A NE2 1 
ATOM   3242  N N   . PHE A 1 466 ? 132.594 164.198 142.446 1.00 49.41  ?  455 PHE A N   1 
ATOM   3243  C CA  . PHE A 1 466 ? 131.298 163.533 142.452 1.00 49.41  ?  455 PHE A CA  1 
ATOM   3244  C C   . PHE A 1 466 ? 130.593 163.640 141.110 1.00 49.41  ?  455 PHE A C   1 
ATOM   3245  O O   . PHE A 1 466 ? 129.657 162.880 140.854 1.00 49.41  ?  455 PHE A O   1 
ATOM   3246  C CB  . PHE A 1 466 ? 130.406 164.121 143.545 1.00 49.41  ?  455 PHE A CB  1 
ATOM   3247  C CG  . PHE A 1 466 ? 130.532 163.429 144.866 1.00 49.41  ?  455 PHE A CG  1 
ATOM   3248  C CD1 . PHE A 1 466 ? 129.919 162.212 145.085 1.00 49.41  ?  455 PHE A CD1 1 
ATOM   3249  C CD2 . PHE A 1 466 ? 131.257 164.001 145.893 1.00 49.41  ?  455 PHE A CD2 1 
ATOM   3250  C CE1 . PHE A 1 466 ? 130.033 161.578 146.296 1.00 49.41  ?  455 PHE A CE1 1 
ATOM   3251  C CE2 . PHE A 1 466 ? 131.371 163.370 147.108 1.00 49.41  ?  455 PHE A CE2 1 
ATOM   3252  C CZ  . PHE A 1 466 ? 130.759 162.159 147.309 1.00 49.41  ?  455 PHE A CZ  1 
ATOM   3253  N N   . ALA A 1 467 ? 131.020 164.570 140.256 1.00 51.45  ?  456 ALA A N   1 
ATOM   3254  C CA  . ALA A 1 467 ? 130.438 164.722 138.931 1.00 51.45  ?  456 ALA A CA  1 
ATOM   3255  C C   . ALA A 1 467 ? 130.775 163.566 138.005 1.00 51.45  ?  456 ALA A C   1 
ATOM   3256  O O   . ALA A 1 467 ? 130.140 163.435 136.955 1.00 51.45  ?  456 ALA A O   1 
ATOM   3257  C CB  . ALA A 1 467 ? 130.904 166.033 138.304 1.00 51.45  ?  456 ALA A CB  1 
ATOM   3258  N N   . GLU A 1 468 ? 131.751 162.732 138.365 1.00 52.47  ?  457 GLU A N   1 
ATOM   3259  C CA  . GLU A 1 468 ? 132.128 161.614 137.510 1.00 52.47  ?  457 GLU A CA  1 
ATOM   3260  C C   . GLU A 1 468 ? 131.092 160.504 137.521 1.00 52.47  ?  457 GLU A C   1 
ATOM   3261  O O   . GLU A 1 468 ? 131.114 159.651 136.630 1.00 52.47  ?  457 GLU A O   1 
ATOM   3262  C CB  . GLU A 1 468 ? 133.487 161.066 137.933 1.00 52.47  ?  457 GLU A CB  1 
ATOM   3263  C CG  . GLU A 1 468 ? 134.646 161.659 137.159 1.00 52.47  ?  457 GLU A CG  1 
ATOM   3264  C CD  . GLU A 1 468 ? 135.055 160.804 135.976 1.00 52.47  ?  457 GLU A CD  1 
ATOM   3265  O OE1 . GLU A 1 468 ? 135.442 159.638 136.190 1.00 52.47  ?  457 GLU A OE1 1 
ATOM   3266  O OE2 . GLU A 1 468 ? 134.991 161.296 134.830 1.00 52.47  -1 457 GLU A OE2 1 
ATOM   3267  N N   . ILE A 1 469 ? 130.175 160.507 138.487 1.00 51.27  ?  458 ILE A N   1 
ATOM   3268  C CA  . ILE A 1 469 ? 129.142 159.475 138.540 1.00 51.27  ?  458 ILE A CA  1 
ATOM   3269  C C   . ILE A 1 469 ? 128.286 159.508 137.278 1.00 51.27  ?  458 ILE A C   1 
ATOM   3270  O O   . ILE A 1 469 ? 128.141 158.498 136.585 1.00 51.27  ?  458 ILE A O   1 
ATOM   3271  C CB  . ILE A 1 469 ? 128.284 159.639 139.805 1.00 51.27  ?  458 ILE A CB  1 
ATOM   3272  C CG1 . ILE A 1 469 ? 129.158 159.572 141.053 1.00 51.27  ?  458 ILE A CG1 1 
ATOM   3273  C CG2 . ILE A 1 469 ? 127.213 158.570 139.858 1.00 51.27  ?  458 ILE A CG2 1 
ATOM   3274  C CD1 . ILE A 1 469 ? 128.396 159.800 142.325 1.00 51.27  ?  458 ILE A CD1 1 
ATOM   3275  N N   . GLY A 1 470 ? 127.674 160.650 136.999 1.00 51.91  ?  459 GLY A N   1 
ATOM   3276  C CA  . GLY A 1 470 ? 126.793 160.754 135.854 1.00 51.91  ?  459 GLY A CA  1 
ATOM   3277  C C   . GLY A 1 470 ? 127.499 160.556 134.540 1.00 51.91  ?  459 GLY A C   1 
ATOM   3278  O O   . GLY A 1 470 ? 126.943 159.974 133.609 1.00 51.91  ?  459 GLY A O   1 
ATOM   3279  N N   . ARG A 1 471 ? 128.728 161.036 134.454 1.00 53.19  ?  460 ARG A N   1 
ATOM   3280  C CA  . ARG A 1 471 ? 129.499 160.875 133.239 1.00 53.19  ?  460 ARG A CA  1 
ATOM   3281  C C   . ARG A 1 471 ? 129.740 159.402 132.923 1.00 53.19  ?  460 ARG A C   1 
ATOM   3282  O O   . ARG A 1 471 ? 129.526 158.967 131.797 1.00 53.19  ?  460 ARG A O   1 
ATOM   3283  C CB  . ARG A 1 471 ? 130.820 161.629 133.363 1.00 53.19  ?  460 ARG A CB  1 
ATOM   3284  C CG  . ARG A 1 471 ? 130.665 163.137 133.397 1.00 53.19  ?  460 ARG A CG  1 
ATOM   3285  C CD  . ARG A 1 471 ? 132.005 163.830 133.228 1.00 53.19  ?  460 ARG A CD  1 
ATOM   3286  N NE  . ARG A 1 471 ? 132.816 163.777 134.439 1.00 53.19  ?  460 ARG A NE  1 
ATOM   3287  C CZ  . ARG A 1 471 ? 132.860 164.746 135.344 1.00 53.19  ?  460 ARG A CZ  1 
ATOM   3288  N NH1 . ARG A 1 471 ? 133.626 164.622 136.418 1.00 53.19  1  460 ARG A NH1 1 
ATOM   3289  N NH2 . ARG A 1 471 ? 132.139 165.845 135.174 1.00 53.19  ?  460 ARG A NH2 1 
ATOM   3290  N N   . LEU A 1 472 ? 130.168 158.634 133.915 1.00 49.25  ?  461 LEU A N   1 
ATOM   3291  C CA  . LEU A 1 472 ? 130.443 157.219 133.704 1.00 49.25  ?  461 LEU A CA  1 
ATOM   3292  C C   . LEU A 1 472 ? 129.166 156.451 133.432 1.00 49.25  ?  461 LEU A C   1 
ATOM   3293  O O   . LEU A 1 472 ? 129.178 155.466 132.703 1.00 49.25  ?  461 LEU A O   1 
ATOM   3294  C CB  . LEU A 1 472 ? 131.179 156.629 134.907 1.00 49.25  ?  461 LEU A CB  1 
ATOM   3295  C CG  . LEU A 1 472 ? 132.556 157.217 135.215 1.00 49.25  ?  461 LEU A CG  1 
ATOM   3296  C CD1 . LEU A 1 472 ? 133.122 156.641 136.503 1.00 49.25  ?  461 LEU A CD1 1 
ATOM   3297  C CD2 . LEU A 1 472 ? 133.509 156.988 134.054 1.00 49.25  ?  461 LEU A CD2 1 
ATOM   3298  N N   . TRP A 1 473 ? 128.062 156.895 134.016 1.00 50.08  ?  462 TRP A N   1 
ATOM   3299  C CA  . TRP A 1 473 ? 126.788 156.245 133.780 1.00 50.08  ?  462 TRP A CA  1 
ATOM   3300  C C   . TRP A 1 473 ? 126.447 156.273 132.304 1.00 50.08  ?  462 TRP A C   1 
ATOM   3301  O O   . TRP A 1 473 ? 125.936 155.302 131.761 1.00 50.08  ?  462 TRP A O   1 
ATOM   3302  C CB  . TRP A 1 473 ? 125.694 156.941 134.570 1.00 50.08  ?  462 TRP A CB  1 
ATOM   3303  C CG  . TRP A 1 473 ? 124.337 156.418 134.288 1.00 50.08  ?  462 TRP A CG  1 
ATOM   3304  C CD1 . TRP A 1 473 ? 123.412 156.952 133.443 1.00 50.08  ?  462 TRP A CD1 1 
ATOM   3305  C CD2 . TRP A 1 473 ? 123.741 155.246 134.847 1.00 50.08  ?  462 TRP A CD2 1 
ATOM   3306  N NE1 . TRP A 1 473 ? 122.275 156.186 133.443 1.00 50.08  ?  462 TRP A NE1 1 
ATOM   3307  C CE2 . TRP A 1 473 ? 122.452 155.132 134.299 1.00 50.08  ?  462 TRP A CE2 1 
ATOM   3308  C CE3 . TRP A 1 473 ? 124.175 154.282 135.761 1.00 50.08  ?  462 TRP A CE3 1 
ATOM   3309  C CZ2 . TRP A 1 473 ? 121.590 154.094 134.633 1.00 50.08  ?  462 TRP A CZ2 1 
ATOM   3310  C CZ3 . TRP A 1 473 ? 123.318 153.255 136.091 1.00 50.08  ?  462 TRP A CZ3 1 
ATOM   3311  C CH2 . TRP A 1 473 ? 122.040 153.166 135.530 1.00 50.08  ?  462 TRP A CH2 1 
ATOM   3312  N N   . ARG A 1 474 ? 126.729 157.390 131.650 1.00 53.35  ?  463 ARG A N   1 
ATOM   3313  C CA  . ARG A 1 474 ? 126.458 157.505 130.226 1.00 53.35  ?  463 ARG A CA  1 
ATOM   3314  C C   . ARG A 1 474 ? 127.475 156.784 129.345 1.00 53.35  ?  463 ARG A C   1 
ATOM   3315  O O   . ARG A 1 474 ? 127.117 156.287 128.284 1.00 53.35  ?  463 ARG A O   1 
ATOM   3316  C CB  . ARG A 1 474 ? 126.397 158.978 129.831 1.00 53.35  ?  463 ARG A CB  1 
ATOM   3317  C CG  . ARG A 1 474 ? 125.406 159.799 130.635 1.00 53.35  ?  463 ARG A CG  1 
ATOM   3318  C CD  . ARG A 1 474 ? 125.289 161.198 130.061 1.00 53.35  ?  463 ARG A CD  1 
ATOM   3319  N NE  . ARG A 1 474 ? 126.595 161.833 129.915 1.00 53.35  ?  463 ARG A NE  1 
ATOM   3320  C CZ  . ARG A 1 474 ? 127.158 162.601 130.840 1.00 53.35  ?  463 ARG A CZ  1 
ATOM   3321  N NH1 . ARG A 1 474 ? 128.351 163.136 130.622 1.00 53.35  1  463 ARG A NH1 1 
ATOM   3322  N NH2 . ARG A 1 474 ? 126.529 162.839 131.982 1.00 53.35  ?  463 ARG A NH2 1 
ATOM   3323  N N   . LYS A 1 475 ? 128.728 156.707 129.771 1.00 50.87  ?  464 LYS A N   1 
ATOM   3324  C CA  . LYS A 1 475 ? 129.771 156.117 128.924 1.00 50.87  ?  464 LYS A CA  1 
ATOM   3325  C C   . LYS A 1 475 ? 130.023 154.625 129.130 1.00 50.87  ?  464 LYS A C   1 
ATOM   3326  O O   . LYS A 1 475 ? 130.067 153.875 128.165 1.00 50.87  ?  464 LYS A O   1 
ATOM   3327  C CB  . LYS A 1 475 ? 131.077 156.886 129.135 1.00 50.87  ?  464 LYS A CB  1 
ATOM   3328  C CG  . LYS A 1 475 ? 130.980 158.358 128.786 1.00 50.87  ?  464 LYS A CG  1 
ATOM   3329  C CD  . LYS A 1 475 ? 132.245 159.098 129.176 1.00 50.87  ?  464 LYS A CD  1 
ATOM   3330  C CE  . LYS A 1 475 ? 132.104 160.587 128.916 1.00 50.87  ?  464 LYS A CE  1 
ATOM   3331  N NZ  . LYS A 1 475 ? 133.307 161.345 129.356 1.00 50.87  1  464 LYS A NZ  1 
ATOM   3332  N N   . ASP A 1 476 ? 130.206 154.198 130.372 1.00 48.29  ?  465 ASP A N   1 
ATOM   3333  C CA  . ASP A 1 476 ? 130.501 152.803 130.664 1.00 48.29  ?  465 ASP A CA  1 
ATOM   3334  C C   . ASP A 1 476 ? 129.974 152.480 132.035 1.00 48.29  ?  465 ASP A C   1 
ATOM   3335  O O   . ASP A 1 476 ? 130.525 152.925 133.036 1.00 48.29  ?  465 ASP A O   1 
ATOM   3336  C CB  . ASP A 1 476 ? 132.007 152.543 130.591 1.00 48.29  ?  465 ASP A CB  1 
ATOM   3337  C CG  . ASP A 1 476 ? 132.361 151.076 130.722 1.00 48.29  ?  465 ASP A CG  1 
ATOM   3338  O OD1 . ASP A 1 476 ? 131.585 150.310 131.324 1.00 48.29  ?  465 ASP A OD1 1 
ATOM   3339  O OD2 . ASP A 1 476 ? 133.434 150.688 130.222 1.00 48.29  -1 465 ASP A OD2 1 
ATOM   3340  N N   . LYS A 1 477 ? 128.924 151.684 132.095 1.00 46.17  ?  466 LYS A N   1 
ATOM   3341  C CA  . LYS A 1 477 ? 128.306 151.377 133.374 1.00 46.17  ?  466 LYS A CA  1 
ATOM   3342  C C   . LYS A 1 477 ? 129.156 150.449 134.222 1.00 46.17  ?  466 LYS A C   1 
ATOM   3343  O O   . LYS A 1 477 ? 128.934 150.353 135.420 1.00 46.17  ?  466 LYS A O   1 
ATOM   3344  C CB  . LYS A 1 477 ? 126.903 150.809 133.159 1.00 46.17  ?  466 LYS A CB  1 
ATOM   3345  C CG  . LYS A 1 477 ? 125.975 151.773 132.442 1.00 46.17  ?  466 LYS A CG  1 
ATOM   3346  C CD  . LYS A 1 477 ? 124.527 151.333 132.529 1.00 46.17  ?  466 LYS A CD  1 
ATOM   3347  C CE  . LYS A 1 477 ? 123.639 152.215 131.670 1.00 46.17  ?  466 LYS A CE  1 
ATOM   3348  N NZ  . LYS A 1 477 ? 123.824 153.656 131.982 1.00 46.17  1  466 LYS A NZ  1 
ATOM   3349  N N   . TYR A 1 478 ? 130.135 149.775 133.628 1.00 43.69  ?  467 TYR A N   1 
ATOM   3350  C CA  . TYR A 1 478 ? 131.031 148.972 134.452 1.00 43.69  ?  467 TYR A CA  1 
ATOM   3351  C C   . TYR A 1 478 ? 131.996 149.859 135.222 1.00 43.69  ?  467 TYR A C   1 
ATOM   3352  O O   . TYR A 1 478 ? 132.301 149.593 136.388 1.00 43.69  ?  467 TYR A O   1 
ATOM   3353  C CB  . TYR A 1 478 ? 131.796 147.973 133.589 1.00 43.69  ?  467 TYR A CB  1 
ATOM   3354  C CG  . TYR A 1 478 ? 130.920 146.984 132.862 1.00 43.69  ?  467 TYR A CG  1 
ATOM   3355  C CD1 . TYR A 1 478 ? 130.442 145.854 133.498 1.00 43.69  ?  467 TYR A CD1 1 
ATOM   3356  C CD2 . TYR A 1 478 ? 130.577 147.183 131.535 1.00 43.69  ?  467 TYR A CD2 1 
ATOM   3357  C CE1 . TYR A 1 478 ? 129.643 144.952 132.837 1.00 43.69  ?  467 TYR A CE1 1 
ATOM   3358  C CE2 . TYR A 1 478 ? 129.781 146.286 130.866 1.00 43.69  ?  467 TYR A CE2 1 
ATOM   3359  C CZ  . TYR A 1 478 ? 129.317 145.172 131.521 1.00 43.69  ?  467 TYR A CZ  1 
ATOM   3360  O OH  . TYR A 1 478 ? 128.521 144.273 130.851 1.00 43.69  ?  467 TYR A OH  1 
ATOM   3361  N N   . ASP A 1 479 ? 132.457 150.944 134.602 1.00 45.55  ?  468 ASP A N   1 
ATOM   3362  C CA  . ASP A 1 479 ? 133.322 151.877 135.311 1.00 45.55  ?  468 ASP A CA  1 
ATOM   3363  C C   . ASP A 1 479 ? 132.528 152.740 136.281 1.00 45.55  ?  468 ASP A C   1 
ATOM   3364  O O   . ASP A 1 479 ? 133.045 153.135 137.331 1.00 45.55  ?  468 ASP A O   1 
ATOM   3365  C CB  . ASP A 1 479 ? 134.087 152.733 134.309 1.00 45.55  ?  468 ASP A CB  1 
ATOM   3366  C CG  . ASP A 1 479 ? 135.149 151.943 133.569 1.00 45.55  ?  468 ASP A CG  1 
ATOM   3367  O OD1 . ASP A 1 479 ? 136.137 151.519 134.202 1.00 45.55  ?  468 ASP A OD1 1 
ATOM   3368  O OD2 . ASP A 1 479 ? 134.999 151.747 132.351 1.00 45.55  -1 468 ASP A OD2 1 
ATOM   3369  N N   . CYS A 1 480 ? 131.267 153.038 135.961 1.00 45.66  ?  469 CYS A N   1 
ATOM   3370  C CA  . CYS A 1 480 ? 130.383 153.652 136.949 1.00 45.66  ?  469 CYS A CA  1 
ATOM   3371  C C   . CYS A 1 480 ? 130.194 152.740 138.153 1.00 45.66  ?  469 CYS A C   1 
ATOM   3372  O O   . CYS A 1 480 ? 130.152 153.204 139.297 1.00 45.66  ?  469 CYS A O   1 
ATOM   3373  C CB  . CYS A 1 480 ? 129.032 153.980 136.321 1.00 45.66  ?  469 CYS A CB  1 
ATOM   3374  S SG  . CYS A 1 480 ? 128.154 155.333 137.112 1.00 45.66  ?  469 CYS A SG  1 
ATOM   3375  N N   . LEU A 1 481 ? 130.071 151.437 137.909 1.00 41.66  ?  470 LEU A N   1 
ATOM   3376  C CA  . LEU A 1 481 ? 129.968 150.484 139.004 1.00 41.66  ?  470 LEU A CA  1 
ATOM   3377  C C   . LEU A 1 481 ? 131.247 150.459 139.827 1.00 41.66  ?  470 LEU A C   1 
ATOM   3378  O O   . LEU A 1 481 ? 131.197 150.401 141.058 1.00 41.66  ?  470 LEU A O   1 
ATOM   3379  C CB  . LEU A 1 481 ? 129.645 149.100 138.444 1.00 41.66  ?  470 LEU A CB  1 
ATOM   3380  C CG  . LEU A 1 481 ? 129.236 147.980 139.394 1.00 41.66  ?  470 LEU A CG  1 
ATOM   3381  C CD1 . LEU A 1 481 ? 127.866 148.239 139.986 1.00 41.66  ?  470 LEU A CD1 1 
ATOM   3382  C CD2 . LEU A 1 481 ? 129.259 146.672 138.646 1.00 41.66  ?  470 LEU A CD2 1 
ATOM   3383  N N   . ILE A 1 482 ? 132.404 150.505 139.166 1.00 42.33  ?  471 ILE A N   1 
ATOM   3384  C CA  . ILE A 1 482 ? 133.675 150.566 139.888 1.00 42.33  ?  471 ILE A CA  1 
ATOM   3385  C C   . ILE A 1 482 ? 133.731 151.810 140.765 1.00 42.33  ?  471 ILE A C   1 
ATOM   3386  O O   . ILE A 1 482 ? 134.125 151.749 141.933 1.00 42.33  ?  471 ILE A O   1 
ATOM   3387  C CB  . ILE A 1 482 ? 134.859 150.519 138.907 1.00 42.33  ?  471 ILE A CB  1 
ATOM   3388  C CG1 . ILE A 1 482 ? 134.907 149.185 138.174 1.00 42.33  ?  471 ILE A CG1 1 
ATOM   3389  C CG2 . ILE A 1 482 ? 136.160 150.737 139.643 1.00 42.33  ?  471 ILE A CG2 1 
ATOM   3390  C CD1 . ILE A 1 482 ? 135.981 149.123 137.129 1.00 42.33  ?  471 ILE A CD1 1 
ATOM   3391  N N   . TRP A 1 483 ? 133.326 152.956 140.216 1.00 42.46  ?  472 TRP A N   1 
ATOM   3392  C CA  . TRP A 1 483 ? 133.310 154.198 140.985 1.00 42.46  ?  472 TRP A CA  1 
ATOM   3393  C C   . TRP A 1 483 ? 132.428 154.073 142.220 1.00 42.46  ?  472 TRP A C   1 
ATOM   3394  O O   . TRP A 1 483 ? 132.871 154.333 143.346 1.00 42.46  ?  472 TRP A O   1 
ATOM   3395  C CB  . TRP A 1 483 ? 132.826 155.345 140.098 1.00 42.46  ?  472 TRP A CB  1 
ATOM   3396  C CG  . TRP A 1 483 ? 133.254 156.720 140.535 1.00 42.46  ?  472 TRP A CG  1 
ATOM   3397  C CD1 . TRP A 1 483 ? 134.177 157.514 139.932 1.00 42.46  ?  472 TRP A CD1 1 
ATOM   3398  C CD2 . TRP A 1 483 ? 132.753 157.471 141.653 1.00 42.46  ?  472 TRP A CD2 1 
ATOM   3399  N NE1 . TRP A 1 483 ? 134.294 158.702 140.605 1.00 42.46  ?  472 TRP A NE1 1 
ATOM   3400  C CE2 . TRP A 1 483 ? 133.431 158.699 141.665 1.00 42.46  ?  472 TRP A CE2 1 
ATOM   3401  C CE3 . TRP A 1 483 ? 131.805 157.217 142.646 1.00 42.46  ?  472 TRP A CE3 1 
ATOM   3402  C CZ2 . TRP A 1 483 ? 133.192 159.667 142.627 1.00 42.46  ?  472 TRP A CZ2 1 
ATOM   3403  C CZ3 . TRP A 1 483 ? 131.572 158.178 143.597 1.00 42.46  ?  472 TRP A CZ3 1 
ATOM   3404  C CH2 . TRP A 1 483 ? 132.260 159.388 143.583 1.00 42.46  ?  472 TRP A CH2 1 
ATOM   3405  N N   . ILE A 1 484 ? 131.166 153.686 142.024 1.00 42.93  ?  473 ILE A N   1 
ATOM   3406  C CA  . ILE A 1 484 ? 130.209 153.657 143.126 1.00 42.93  ?  473 ILE A CA  1 
ATOM   3407  C C   . ILE A 1 484 ? 130.612 152.625 144.170 1.00 42.93  ?  473 ILE A C   1 
ATOM   3408  O O   . ILE A 1 484 ? 130.523 152.877 145.376 1.00 42.93  ?  473 ILE A O   1 
ATOM   3409  C CB  . ILE A 1 484 ? 128.792 153.399 142.587 1.00 42.93  ?  473 ILE A CB  1 
ATOM   3410  C CG1 . ILE A 1 484 ? 128.374 154.526 141.648 1.00 42.93  ?  473 ILE A CG1 1 
ATOM   3411  C CG2 . ILE A 1 484 ? 127.804 153.281 143.724 1.00 42.93  ?  473 ILE A CG2 1 
ATOM   3412  C CD1 . ILE A 1 484 ? 127.082 154.269 140.928 1.00 42.93  ?  473 ILE A CD1 1 
ATOM   3413  N N   . MET A 1 485 ? 131.078 151.457 143.735 1.00 42.90  ?  474 MET A N   1 
ATOM   3414  C CA  . MET A 1 485 ? 131.435 150.422 144.692 1.00 42.90  ?  474 MET A CA  1 
ATOM   3415  C C   . MET A 1 485 ? 132.720 150.753 145.428 1.00 42.90  ?  474 MET A C   1 
ATOM   3416  O O   . MET A 1 485 ? 132.847 150.420 146.608 1.00 42.90  ?  474 MET A O   1 
ATOM   3417  C CB  . MET A 1 485 ? 131.548 149.076 143.987 1.00 42.90  ?  474 MET A CB  1 
ATOM   3418  C CG  . MET A 1 485 ? 130.228 148.584 143.431 1.00 42.90  ?  474 MET A CG  1 
ATOM   3419  S SD  . MET A 1 485 ? 129.003 148.289 144.709 1.00 42.90  ?  474 MET A SD  1 
ATOM   3420  C CE  . MET A 1 485 ? 129.671 146.812 145.456 1.00 42.90  ?  474 MET A CE  1 
ATOM   3421  N N   . THR A 1 486 ? 133.672 151.425 144.777 1.00 41.90  ?  475 THR A N   1 
ATOM   3422  C CA  . THR A 1 486 ? 134.862 151.887 145.480 1.00 41.90  ?  475 THR A CA  1 
ATOM   3423  C C   . THR A 1 486 ? 134.499 152.931 146.525 1.00 41.90  ?  475 THR A C   1 
ATOM   3424  O O   . THR A 1 486 ? 135.006 152.902 147.654 1.00 41.90  ?  475 THR A O   1 
ATOM   3425  C CB  . THR A 1 486 ? 135.868 152.451 144.482 1.00 41.90  ?  475 THR A CB  1 
ATOM   3426  O OG1 . THR A 1 486 ? 136.079 151.495 143.439 1.00 41.90  ?  475 THR A OG1 1 
ATOM   3427  C CG2 . THR A 1 486 ? 137.181 152.739 145.165 1.00 41.90  ?  475 THR A CG2 1 
ATOM   3428  N N   . PHE A 1 487 ? 133.607 153.856 146.171 1.00 41.69  ?  476 PHE A N   1 
ATOM   3429  C CA  . PHE A 1 487 ? 133.147 154.848 147.136 1.00 41.69  ?  476 PHE A CA  1 
ATOM   3430  C C   . PHE A 1 487 ? 132.495 154.182 148.340 1.00 41.69  ?  476 PHE A C   1 
ATOM   3431  O O   . PHE A 1 487 ? 132.802 154.514 149.490 1.00 41.69  ?  476 PHE A O   1 
ATOM   3432  C CB  . PHE A 1 487 ? 132.175 155.813 146.462 1.00 41.69  ?  476 PHE A CB  1 
ATOM   3433  C CG  . PHE A 1 487 ? 131.778 156.971 147.324 1.00 41.69  ?  476 PHE A CG  1 
ATOM   3434  C CD1 . PHE A 1 487 ? 132.568 158.097 147.393 1.00 41.69  ?  476 PHE A CD1 1 
ATOM   3435  C CD2 . PHE A 1 487 ? 130.615 156.933 148.066 1.00 41.69  ?  476 PHE A CD2 1 
ATOM   3436  C CE1 . PHE A 1 487 ? 132.209 159.155 148.184 1.00 41.69  ?  476 PHE A CE1 1 
ATOM   3437  C CE2 . PHE A 1 487 ? 130.257 157.991 148.857 1.00 41.69  ?  476 PHE A CE2 1 
ATOM   3438  C CZ  . PHE A 1 487 ? 131.055 159.103 148.914 1.00 41.69  ?  476 PHE A CZ  1 
ATOM   3439  N N   . ILE A 1 488 ? 131.597 153.229 148.092 1.00 43.02  ?  477 ILE A N   1 
ATOM   3440  C CA  . ILE A 1 488 ? 130.873 152.597 149.190 1.00 43.02  ?  477 ILE A CA  1 
ATOM   3441  C C   . ILE A 1 488 ? 131.797 151.729 150.033 1.00 43.02  ?  477 ILE A C   1 
ATOM   3442  O O   . ILE A 1 488 ? 131.681 151.712 151.260 1.00 43.02  ?  477 ILE A O   1 
ATOM   3443  C CB  . ILE A 1 488 ? 129.679 151.798 148.642 1.00 43.02  ?  477 ILE A CB  1 
ATOM   3444  C CG1 . ILE A 1 488 ? 128.684 152.738 147.970 1.00 43.02  ?  477 ILE A CG1 1 
ATOM   3445  C CG2 . ILE A 1 488 ? 128.996 151.032 149.753 1.00 43.02  ?  477 ILE A CG2 1 
ATOM   3446  C CD1 . ILE A 1 488 ? 127.513 152.035 147.355 1.00 43.02  ?  477 ILE A CD1 1 
ATOM   3447  N N   . PHE A 1 489 ? 132.722 150.998 149.411 1.00 43.89  ?  478 PHE A N   1 
ATOM   3448  C CA  . PHE A 1 489 ? 133.658 150.180 150.174 1.00 43.89  ?  478 PHE A CA  1 
ATOM   3449  C C   . PHE A 1 489 ? 134.568 151.045 151.034 1.00 43.89  ?  478 PHE A C   1 
ATOM   3450  O O   . PHE A 1 489 ? 134.898 150.685 152.166 1.00 43.89  ?  478 PHE A O   1 
ATOM   3451  C CB  . PHE A 1 489 ? 134.493 149.315 149.230 1.00 43.89  ?  478 PHE A CB  1 
ATOM   3452  C CG  . PHE A 1 489 ? 133.761 148.129 148.680 1.00 43.89  ?  478 PHE A CG  1 
ATOM   3453  C CD1 . PHE A 1 489 ? 132.836 147.449 149.444 1.00 43.89  ?  478 PHE A CD1 1 
ATOM   3454  C CD2 . PHE A 1 489 ? 134.008 147.689 147.393 1.00 43.89  ?  478 PHE A CD2 1 
ATOM   3455  C CE1 . PHE A 1 489 ? 132.172 146.359 148.931 1.00 43.89  ?  478 PHE A CE1 1 
ATOM   3456  C CE2 . PHE A 1 489 ? 133.348 146.603 146.879 1.00 43.89  ?  478 PHE A CE2 1 
ATOM   3457  C CZ  . PHE A 1 489 ? 132.429 145.937 147.647 1.00 43.89  ?  478 PHE A CZ  1 
ATOM   3458  N N   . THR A 1 490 ? 134.992 152.195 150.511 1.00 43.41  ?  479 THR A N   1 
ATOM   3459  C CA  . THR A 1 490 ? 135.864 153.078 151.269 1.00 43.41  ?  479 THR A CA  1 
ATOM   3460  C C   . THR A 1 490 ? 135.133 153.825 152.376 1.00 43.41  ?  479 THR A C   1 
ATOM   3461  O O   . THR A 1 490 ? 135.738 154.110 153.413 1.00 43.41  ?  479 THR A O   1 
ATOM   3462  C CB  . THR A 1 490 ? 136.534 154.070 150.322 1.00 43.41  ?  479 THR A CB  1 
ATOM   3463  O OG1 . THR A 1 490 ? 136.992 153.376 149.158 1.00 43.41  ?  479 THR A OG1 1 
ATOM   3464  C CG2 . THR A 1 490 ? 137.703 154.743 150.988 1.00 43.41  ?  479 THR A CG2 1 
ATOM   3465  N N   . ILE A 1 491 ? 133.854 154.142 152.188 1.00 44.54  ?  480 ILE A N   1 
ATOM   3466  C CA  . ILE A 1 491 ? 133.106 154.834 153.232 1.00 44.54  ?  480 ILE A CA  1 
ATOM   3467  C C   . ILE A 1 491 ? 132.674 153.854 154.315 1.00 44.54  ?  480 ILE A C   1 
ATOM   3468  O O   . ILE A 1 491 ? 132.833 154.116 155.511 1.00 44.54  ?  480 ILE A O   1 
ATOM   3469  C CB  . ILE A 1 491 ? 131.903 155.577 152.629 1.00 44.54  ?  480 ILE A CB  1 
ATOM   3470  C CG1 . ILE A 1 491 ? 132.371 156.801 151.846 1.00 44.54  ?  480 ILE A CG1 1 
ATOM   3471  C CG2 . ILE A 1 491 ? 130.929 155.984 153.713 1.00 44.54  ?  480 ILE A CG2 1 
ATOM   3472  C CD1 . ILE A 1 491 ? 132.905 157.902 152.707 1.00 44.54  ?  480 ILE A CD1 1 
ATOM   3473  N N   . VAL A 1 492 ? 132.131 152.707 153.916 1.00 46.79  ?  481 VAL A N   1 
ATOM   3474  C CA  . VAL A 1 492 ? 131.627 151.728 154.868 1.00 46.79  ?  481 VAL A CA  1 
ATOM   3475  C C   . VAL A 1 492 ? 132.804 151.043 155.547 1.00 46.79  ?  481 VAL A C   1 
ATOM   3476  O O   . VAL A 1 492 ? 133.018 151.220 156.747 1.00 46.79  ?  481 VAL A O   1 
ATOM   3477  C CB  . VAL A 1 492 ? 130.704 150.709 154.180 1.00 46.79  ?  481 VAL A CB  1 
ATOM   3478  C CG1 . VAL A 1 492 ? 130.447 149.526 155.088 1.00 46.79  ?  481 VAL A CG1 1 
ATOM   3479  C CG2 . VAL A 1 492 ? 129.400 151.374 153.793 1.00 46.79  ?  481 VAL A CG2 1 
ATOM   3480  N N   . LEU A 1 493 ? 133.597 150.298 154.787 1.00 47.27  ?  482 LEU A N   1 
ATOM   3481  C CA  . LEU A 1 493 ? 134.800 149.686 155.333 1.00 47.27  ?  482 LEU A CA  1 
ATOM   3482  C C   . LEU A 1 493 ? 135.855 150.774 155.517 1.00 47.27  ?  482 LEU A C   1 
ATOM   3483  O O   . LEU A 1 493 ? 135.585 151.970 155.394 1.00 47.27  ?  482 LEU A O   1 
ATOM   3484  C CB  . LEU A 1 493 ? 135.295 148.561 154.430 1.00 47.27  ?  482 LEU A CB  1 
ATOM   3485  C CG  . LEU A 1 493 ? 134.273 147.541 153.925 1.00 47.27  ?  482 LEU A CG  1 
ATOM   3486  C CD1 . LEU A 1 493 ? 134.902 146.628 152.896 1.00 47.27  ?  482 LEU A CD1 1 
ATOM   3487  C CD2 . LEU A 1 493 ? 133.712 146.736 155.075 1.00 47.27  ?  482 LEU A CD2 1 
ATOM   3488  N N   . GLY A 1 494 ? 137.079 150.374 155.812 1.00 46.79  ?  483 GLY A N   1 
ATOM   3489  C CA  . GLY A 1 494 ? 138.127 151.339 156.049 1.00 46.79  ?  483 GLY A CA  1 
ATOM   3490  C C   . GLY A 1 494 ? 138.613 152.012 154.780 1.00 46.79  ?  483 GLY A C   1 
ATOM   3491  O O   . GLY A 1 494 ? 138.016 151.929 153.709 1.00 46.79  ?  483 GLY A O   1 
ATOM   3492  N N   . LEU A 1 495 ? 139.731 152.719 154.928 1.00 46.76  ?  484 LEU A N   1 
ATOM   3493  C CA  . LEU A 1 495 ? 140.485 153.197 153.777 1.00 46.76  ?  484 LEU A CA  1 
ATOM   3494  C C   . LEU A 1 495 ? 141.452 152.143 153.262 1.00 46.76  ?  484 LEU A C   1 
ATOM   3495  O O   . LEU A 1 495 ? 141.845 152.199 152.093 1.00 46.76  ?  484 LEU A O   1 
ATOM   3496  C CB  . LEU A 1 495 ? 141.255 154.466 154.139 1.00 46.76  ?  484 LEU A CB  1 
ATOM   3497  C CG  . LEU A 1 495 ? 140.492 155.783 154.191 1.00 46.76  ?  484 LEU A CG  1 
ATOM   3498  C CD1 . LEU A 1 495 ? 141.228 156.773 155.059 1.00 46.76  ?  484 LEU A CD1 1 
ATOM   3499  C CD2 . LEU A 1 495 ? 140.332 156.335 152.806 1.00 46.76  ?  484 LEU A CD2 1 
ATOM   3500  N N   . GLY A 1 496 ? 141.849 151.195 154.105 1.00 47.71  ?  485 GLY A N   1 
ATOM   3501  C CA  . GLY A 1 496 ? 142.742 150.132 153.692 1.00 47.71  ?  485 GLY A CA  1 
ATOM   3502  C C   . GLY A 1 496 ? 142.001 148.881 153.277 1.00 47.71  ?  485 GLY A C   1 
ATOM   3503  O O   . GLY A 1 496 ? 142.387 148.218 152.313 1.00 47.71  ?  485 GLY A O   1 
ATOM   3504  N N   . LEU A 1 497 ? 140.954 148.534 154.007 1.00 47.60  ?  486 LEU A N   1 
ATOM   3505  C CA  . LEU A 1 497 ? 140.154 147.396 153.611 1.00 47.60  ?  486 LEU A CA  1 
ATOM   3506  C C   . LEU A 1 497 ? 139.279 147.816 152.456 1.00 47.60  ?  486 LEU A C   1 
ATOM   3507  O O   . LEU A 1 497 ? 138.974 147.013 151.584 1.00 47.60  ?  486 LEU A O   1 
ATOM   3508  C CB  . LEU A 1 497 ? 139.310 146.884 154.770 1.00 47.60  ?  486 LEU A CB  1 
ATOM   3509  C CG  . LEU A 1 497 ? 140.005 145.872 155.677 1.00 47.60  ?  486 LEU A CG  1 
ATOM   3510  C CD1 . LEU A 1 497 ? 139.080 145.464 156.810 1.00 47.60  ?  486 LEU A CD1 1 
ATOM   3511  C CD2 . LEU A 1 497 ? 140.429 144.660 154.861 1.00 47.60  ?  486 LEU A CD2 1 
ATOM   3512  N N   . GLY A 1 498 ? 138.887 149.082 152.439 1.00 43.95  ?  487 GLY A N   1 
ATOM   3513  C CA  . GLY A 1 498 ? 138.070 149.581 151.358 1.00 43.95  ?  487 GLY A CA  1 
ATOM   3514  C C   . GLY A 1 498 ? 138.788 149.464 150.037 1.00 43.95  ?  487 GLY A C   1 
ATOM   3515  O O   . GLY A 1 498 ? 138.206 149.012 149.060 1.00 43.95  ?  487 GLY A O   1 
ATOM   3516  N N   . LEU A 1 499 ? 140.055 149.856 150.002 1.00 42.97  ?  488 LEU A N   1 
ATOM   3517  C CA  . LEU A 1 499 ? 140.827 149.794 148.769 1.00 42.97  ?  488 LEU A CA  1 
ATOM   3518  C C   . LEU A 1 499 ? 141.035 148.364 148.298 1.00 42.97  ?  488 LEU A C   1 
ATOM   3519  O O   . LEU A 1 499 ? 140.948 148.087 147.108 1.00 42.97  ?  488 LEU A O   1 
ATOM   3520  C CB  . LEU A 1 499 ? 142.182 150.478 148.939 1.00 42.97  ?  488 LEU A CB  1 
ATOM   3521  C CG  . LEU A 1 499 ? 143.025 150.534 147.667 1.00 42.97  ?  488 LEU A CG  1 
ATOM   3522  C CD1 . LEU A 1 499 ? 142.329 151.372 146.607 1.00 42.97  ?  488 LEU A CD1 1 
ATOM   3523  C CD2 . LEU A 1 499 ? 144.409 151.080 147.963 1.00 42.97  ?  488 LEU A CD2 1 
ATOM   3524  N N   . ALA A 1 500 ? 141.319 147.461 149.225 1.00 41.34  ?  489 ALA A N   1 
ATOM   3525  C CA  . ALA A 1 500 ? 141.514 146.063 148.871 1.00 41.34  ?  489 ALA A CA  1 
ATOM   3526  C C   . ALA A 1 500 ? 140.228 145.488 148.313 1.00 41.34  ?  489 ALA A C   1 
ATOM   3527  O O   . ALA A 1 500 ? 140.242 144.797 147.296 1.00 41.34  ?  489 ALA A O   1 
ATOM   3528  C CB  . ALA A 1 500 ? 141.970 145.279 150.084 1.00 41.34  ?  489 ALA A CB  1 
ATOM   3529  N N   . ALA A 1 501 ? 139.111 145.780 148.965 1.00 41.11  ?  490 ALA A N   1 
ATOM   3530  C CA  . ALA A 1 501 ? 137.822 145.320 148.477 1.00 41.11  ?  490 ALA A CA  1 
ATOM   3531  C C   . ALA A 1 501 ? 137.522 145.944 147.126 1.00 41.11  ?  490 ALA A C   1 
ATOM   3532  O O   . ALA A 1 501 ? 136.980 145.287 146.240 1.00 41.11  ?  490 ALA A O   1 
ATOM   3533  C CB  . ALA A 1 501 ? 136.730 145.659 149.476 1.00 41.11  ?  490 ALA A CB  1 
ATOM   3534  N N   . SER A 1 502 ? 137.886 147.206 146.961 1.00 40.69  ?  491 SER A N   1 
ATOM   3535  C CA  . SER A 1 502 ? 137.634 147.907 145.708 1.00 40.69  ?  491 SER A CA  1 
ATOM   3536  C C   . SER A 1 502 ? 138.438 147.348 144.537 1.00 40.69  ?  491 SER A C   1 
ATOM   3537  O O   . SER A 1 502 ? 137.938 147.276 143.421 1.00 40.69  ?  491 SER A O   1 
ATOM   3538  C CB  . SER A 1 502 ? 137.903 149.402 145.886 1.00 40.69  ?  491 SER A CB  1 
ATOM   3539  O OG  . SER A 1 502 ? 137.100 149.940 146.918 1.00 40.69  ?  491 SER A OG  1 
ATOM   3540  N N   . VAL A 1 503 ? 139.679 146.956 144.787 1.00 40.69  ?  492 VAL A N   1 
ATOM   3541  C CA  . VAL A 1 503 ? 140.509 146.397 143.734 1.00 40.69  ?  492 VAL A CA  1 
ATOM   3542  C C   . VAL A 1 503 ? 139.973 145.040 143.304 1.00 40.69  ?  492 VAL A C   1 
ATOM   3543  O O   . VAL A 1 503 ? 139.976 144.719 142.121 1.00 40.69  ?  492 VAL A O   1 
ATOM   3544  C CB  . VAL A 1 503 ? 141.984 146.281 144.169 1.00 40.69  ?  492 VAL A CB  1 
ATOM   3545  C CG1 . VAL A 1 503 ? 142.803 145.578 143.099 1.00 40.69  ?  492 VAL A CG1 1 
ATOM   3546  C CG2 . VAL A 1 503 ? 142.557 147.656 144.464 1.00 40.69  ?  492 VAL A CG2 1 
ATOM   3547  N N   . ALA A 1 504 ? 139.500 144.252 144.260 1.00 40.37  ?  493 ALA A N   1 
ATOM   3548  C CA  . ALA A 1 504 ? 138.940 142.947 143.943 1.00 40.37  ?  493 ALA A CA  1 
ATOM   3549  C C   . ALA A 1 504 ? 137.676 143.059 143.094 1.00 40.37  ?  493 ALA A C   1 
ATOM   3550  O O   . ALA A 1 504 ? 137.541 142.341 142.112 1.00 40.37  ?  493 ALA A O   1 
ATOM   3551  C CB  . ALA A 1 504 ? 138.667 142.172 145.218 1.00 40.37  ?  493 ALA A CB  1 
ATOM   3552  N N   . PHE A 1 505 ? 136.751 143.945 143.459 1.00 41.02  ?  494 PHE A N   1 
ATOM   3553  C CA  . PHE A 1 505 ? 135.553 144.160 142.657 1.00 41.02  ?  494 PHE A CA  1 
ATOM   3554  C C   . PHE A 1 505 ? 135.885 144.698 141.271 1.00 41.02  ?  494 PHE A C   1 
ATOM   3555  O O   . PHE A 1 505 ? 135.183 144.390 140.300 1.00 41.02  ?  494 PHE A O   1 
ATOM   3556  C CB  . PHE A 1 505 ? 134.605 145.110 143.377 1.00 41.02  ?  494 PHE A CB  1 
ATOM   3557  C CG  . PHE A 1 505 ? 133.264 145.214 142.729 1.00 41.02  ?  494 PHE A CG  1 
ATOM   3558  C CD1 . PHE A 1 505 ? 132.978 146.257 141.870 1.00 41.02  ?  494 PHE A CD1 1 
ATOM   3559  C CD2 . PHE A 1 505 ? 132.295 144.260 142.964 1.00 41.02  ?  494 PHE A CD2 1 
ATOM   3560  C CE1 . PHE A 1 505 ? 131.753 146.344 141.267 1.00 41.02  ?  494 PHE A CE1 1 
ATOM   3561  C CE2 . PHE A 1 505 ? 131.068 144.349 142.361 1.00 41.02  ?  494 PHE A CE2 1 
ATOM   3562  C CZ  . PHE A 1 505 ? 130.795 145.393 141.515 1.00 41.02  ?  494 PHE A CZ  1 
ATOM   3563  N N   . GLN A 1 506 ? 136.942 145.494 141.149 1.00 39.07  ?  495 GLN A N   1 
ATOM   3564  C CA  . GLN A 1 506 ? 137.327 146.000 139.841 1.00 39.07  ?  495 GLN A CA  1 
ATOM   3565  C C   . GLN A 1 506 ? 137.876 144.887 138.963 1.00 39.07  ?  495 GLN A C   1 
ATOM   3566  O O   . GLN A 1 506 ? 137.668 144.890 137.745 1.00 39.07  ?  495 GLN A O   1 
ATOM   3567  C CB  . GLN A 1 506 ? 138.340 147.125 140.013 1.00 39.07  ?  495 GLN A CB  1 
ATOM   3568  C CG  . GLN A 1 506 ? 139.218 147.367 138.832 1.00 39.07  ?  495 GLN A CG  1 
ATOM   3569  C CD  . GLN A 1 506 ? 140.534 147.945 139.243 1.00 39.07  ?  495 GLN A CD  1 
ATOM   3570  O OE1 . GLN A 1 506 ? 140.800 149.123 139.031 1.00 39.07  ?  495 GLN A OE1 1 
ATOM   3571  N NE2 . GLN A 1 506 ? 141.379 147.117 139.818 1.00 39.07  ?  495 GLN A NE2 1 
ATOM   3572  N N   . LEU A 1 507 ? 138.573 143.918 139.561 1.00 39.86  ?  496 LEU A N   1 
ATOM   3573  C CA  . LEU A 1 507 ? 138.966 142.732 138.809 1.00 39.86  ?  496 LEU A CA  1 
ATOM   3574  C C   . LEU A 1 507 ? 137.761 141.888 138.435 1.00 39.86  ?  496 LEU A C   1 
ATOM   3575  O O   . LEU A 1 507 ? 137.769 141.220 137.398 1.00 39.86  ?  496 LEU A O   1 
ATOM   3576  C CB  . LEU A 1 507 ? 139.951 141.888 139.613 1.00 39.86  ?  496 LEU A CB  1 
ATOM   3577  C CG  . LEU A 1 507 ? 141.280 142.481 140.057 1.00 39.86  ?  496 LEU A CG  1 
ATOM   3578  C CD1 . LEU A 1 507 ? 142.021 141.449 140.878 1.00 39.86  ?  496 LEU A CD1 1 
ATOM   3579  C CD2 . LEU A 1 507 ? 142.107 142.928 138.874 1.00 39.86  ?  496 LEU A CD2 1 
ATOM   3580  N N   . LEU A 1 508 ? 136.727 141.888 139.275 1.00 39.74  ?  497 LEU A N   1 
ATOM   3581  C CA  . LEU A 1 508 ? 135.518 141.126 138.970 1.00 39.74  ?  497 LEU A CA  1 
ATOM   3582  C C   . LEU A 1 508 ? 134.723 141.744 137.823 1.00 39.74  ?  497 LEU A C   1 
ATOM   3583  O O   . LEU A 1 508 ? 134.072 141.024 137.060 1.00 39.74  ?  497 LEU A O   1 
ATOM   3584  C CB  . LEU A 1 508 ? 134.652 141.016 140.221 1.00 39.74  ?  497 LEU A CB  1 
ATOM   3585  C CG  . LEU A 1 508 ? 133.422 140.114 140.171 1.00 39.74  ?  497 LEU A CG  1 
ATOM   3586  C CD1 . LEU A 1 508 ? 133.806 138.674 139.881 1.00 39.74  ?  497 LEU A CD1 1 
ATOM   3587  C CD2 . LEU A 1 508 ? 132.663 140.222 141.477 1.00 39.74  ?  497 LEU A CD2 1 
ATOM   3588  N N   . THR A 1 509 ? 134.745 143.070 137.692 1.00 40.21  ?  498 THR A N   1 
ATOM   3589  C CA  . THR A 1 509 ? 134.036 143.689 136.573 1.00 40.21  ?  498 THR A CA  1 
ATOM   3590  C C   . THR A 1 509 ? 134.638 143.299 135.229 1.00 40.21  ?  498 THR A C   1 
ATOM   3591  O O   . THR A 1 509 ? 133.925 143.270 134.220 1.00 40.21  ?  498 THR A O   1 
ATOM   3592  C CB  . THR A 1 509 ? 134.018 145.209 136.710 1.00 40.21  ?  498 THR A CB  1 
ATOM   3593  O OG1 . THR A 1 509 ? 135.360 145.710 136.677 1.00 40.21  ?  498 THR A OG1 1 
ATOM   3594  C CG2 . THR A 1 509 ? 133.348 145.620 138.002 1.00 40.21  ?  498 THR A CG2 1 
ATOM   3595  N N   . ILE A 1 510 ? 135.940 143.005 135.187 1.00 40.14  ?  499 ILE A N   1 
ATOM   3596  C CA  . ILE A 1 510 ? 136.560 142.528 133.953 1.00 40.14  ?  499 ILE A CA  1 
ATOM   3597  C C   . ILE A 1 510 ? 135.917 141.225 133.514 1.00 40.14  ?  499 ILE A C   1 
ATOM   3598  O O   . ILE A 1 510 ? 135.779 140.950 132.318 1.00 40.14  ?  499 ILE A O   1 
ATOM   3599  C CB  . ILE A 1 510 ? 138.081 142.375 134.143 1.00 40.14  ?  499 ILE A CB  1 
ATOM   3600  C CG1 . ILE A 1 510 ? 138.720 143.715 134.487 1.00 40.14  ?  499 ILE A CG1 1 
ATOM   3601  C CG2 . ILE A 1 510 ? 138.731 141.821 132.894 1.00 40.14  ?  499 ILE A CG2 1 
ATOM   3602  C CD1 . ILE A 1 510 ? 138.554 144.750 133.406 1.00 40.14  ?  499 ILE A CD1 1 
ATOM   3603  N N   . VAL A 1 511 ? 135.510 140.404 134.481 1.00 39.57  ?  500 VAL A N   1 
ATOM   3604  C CA  . VAL A 1 511 ? 134.772 139.185 134.175 1.00 39.57  ?  500 VAL A CA  1 
ATOM   3605  C C   . VAL A 1 511 ? 133.342 139.524 133.777 1.00 39.57  ?  500 VAL A C   1 
ATOM   3606  O O   . VAL A 1 511 ? 132.779 138.923 132.860 1.00 39.57  ?  500 VAL A O   1 
ATOM   3607  C CB  . VAL A 1 511 ? 134.818 138.226 135.377 1.00 39.57  ?  500 VAL A CB  1 
ATOM   3608  C CG1 . VAL A 1 511 ? 133.850 137.081 135.192 1.00 39.57  ?  500 VAL A CG1 1 
ATOM   3609  C CG2 . VAL A 1 511 ? 136.227 137.711 135.577 1.00 39.57  ?  500 VAL A CG2 1 
ATOM   3610  N N   . PHE A 1 512 ? 132.738 140.491 134.469 1.00 40.02  ?  501 PHE A N   1 
ATOM   3611  C CA  . PHE A 1 512 ? 131.388 140.930 134.122 1.00 40.02  ?  501 PHE A CA  1 
ATOM   3612  C C   . PHE A 1 512 ? 131.288 141.328 132.653 1.00 40.02  ?  501 PHE A C   1 
ATOM   3613  O O   . PHE A 1 512 ? 130.276 141.055 131.998 1.00 40.02  ?  501 PHE A O   1 
ATOM   3614  C CB  . PHE A 1 512 ? 130.961 142.104 135.000 1.00 40.02  ?  501 PHE A CB  1 
ATOM   3615  C CG  . PHE A 1 512 ? 130.671 141.737 136.422 1.00 40.02  ?  501 PHE A CG  1 
ATOM   3616  C CD1 . PHE A 1 512 ? 130.675 140.423 136.832 1.00 40.02  ?  501 PHE A CD1 1 
ATOM   3617  C CD2 . PHE A 1 512 ? 130.395 142.717 137.352 1.00 40.02  ?  501 PHE A CD2 1 
ATOM   3618  C CE1 . PHE A 1 512 ? 130.409 140.094 138.139 1.00 40.02  ?  501 PHE A CE1 1 
ATOM   3619  C CE2 . PHE A 1 512 ? 130.131 142.393 138.659 1.00 40.02  ?  501 PHE A CE2 1 
ATOM   3620  C CZ  . PHE A 1 512 ? 130.137 141.081 139.052 1.00 40.02  ?  501 PHE A CZ  1 
ATOM   3621  N N   . ARG A 1 513 ? 132.319 141.985 132.120 1.00 42.15  ?  502 ARG A N   1 
ATOM   3622  C CA  . ARG A 1 513 ? 132.288 142.409 130.722 1.00 42.15  ?  502 ARG A CA  1 
ATOM   3623  C C   . ARG A 1 513 ? 132.272 141.214 129.779 1.00 42.15  ?  502 ARG A C   1 
ATOM   3624  O O   . ARG A 1 513 ? 131.454 141.148 128.856 1.00 42.15  ?  502 ARG A O   1 
ATOM   3625  C CB  . ARG A 1 513 ? 133.484 143.301 130.408 1.00 42.15  ?  502 ARG A CB  1 
ATOM   3626  C CG  . ARG A 1 513 ? 133.624 144.495 131.303 1.00 42.15  ?  502 ARG A CG  1 
ATOM   3627  C CD  . ARG A 1 513 ? 134.932 145.189 131.040 1.00 42.15  ?  502 ARG A CD  1 
ATOM   3628  N NE  . ARG A 1 513 ? 134.999 146.492 131.686 1.00 42.15  ?  502 ARG A NE  1 
ATOM   3629  C CZ  . ARG A 1 513 ? 134.609 147.620 131.110 1.00 42.15  ?  502 ARG A CZ  1 
ATOM   3630  N NH1 . ARG A 1 513 ? 134.701 148.767 131.765 1.00 42.15  1  502 ARG A NH1 1 
ATOM   3631  N NH2 . ARG A 1 513 ? 134.123 147.599 129.880 1.00 42.15  ?  502 ARG A NH2 1 
ATOM   3632  N N   . THR A 1 514 ? 133.171 140.238 130.075 1.00 41.65  ?  503 THR A N   1 
ATOM   3633  C CA  . THR A 1 514 ? 133.341 139.075 129.201 1.00 41.65  ?  503 THR A CA  1 
ATOM   3634  C C   . THR A 1 514 ? 132.575 137.873 129.674 1.00 41.65  ?  503 THR A C   1 
ATOM   3635  O O   . THR A 1 514 ? 132.969 136.746 129.419 1.00 41.65  ?  503 THR A O   1 
ATOM   3636  C CB  . THR A 1 514 ? 134.827 138.716 129.152 1.00 41.65  ?  503 THR A CB  1 
ATOM   3637  O OG1 . THR A 1 514 ? 135.321 138.579 130.488 1.00 41.65  ?  503 THR A OG1 1 
ATOM   3638  C CG2 . THR A 1 514 ? 135.603 139.809 128.451 1.00 41.65  ?  503 THR A CG2 1 
ATOM   3639  N N   . GLN A 1 515 ? 131.430 138.100 130.289 1.00 40.78  ?  504 GLN A N   1 
ATOM   3640  C CA  . GLN A 1 515 ? 130.670 137.033 130.924 1.00 40.78  ?  504 GLN A CA  1 
ATOM   3641  C C   . GLN A 1 515 ? 129.608 136.459 129.996 1.00 40.78  ?  504 GLN A C   1 
ATOM   3642  O O   . GLN A 1 515 ? 129.495 135.239 129.854 1.00 40.78  ?  504 GLN A O   1 
ATOM   3643  C CB  . GLN A 1 515 ? 130.021 137.572 132.196 1.00 40.78  ?  504 GLN A CB  1 
ATOM   3644  C CG  . GLN A 1 515 ? 129.785 136.566 133.274 1.00 40.78  ?  504 GLN A CG  1 
ATOM   3645  C CD  . GLN A 1 515 ? 129.015 137.165 134.410 1.00 40.78  ?  504 GLN A CD  1 
ATOM   3646  O OE1 . GLN A 1 515 ? 128.446 138.240 134.280 1.00 40.78  ?  504 GLN A OE1 1 
ATOM   3647  N NE2 . GLN A 1 515 ? 128.986 136.477 135.533 1.00 40.78  ?  504 GLN A NE2 1 
ATOM   3648  N N   . PHE A 1 516 ? 128.814 137.330 129.373 1.00 39.99  ?  505 PHE A N   1 
ATOM   3649  C CA  . PHE A 1 516 ? 127.752 136.950 128.448 1.00 39.99  ?  505 PHE A CA  1 
ATOM   3650  C C   . PHE A 1 516 ? 127.999 137.681 127.136 1.00 39.99  ?  505 PHE A C   1 
ATOM   3651  O O   . PHE A 1 516 ? 127.354 138.701 126.856 1.00 39.99  ?  505 PHE A O   1 
ATOM   3652  C CB  . PHE A 1 516 ? 126.373 137.294 129.007 1.00 39.99  ?  505 PHE A CB  1 
ATOM   3653  C CG  . PHE A 1 516 ? 126.134 136.795 130.402 1.00 39.99  ?  505 PHE A CG  1 
ATOM   3654  C CD1 . PHE A 1 516 ? 126.345 135.473 130.729 1.00 39.99  ?  505 PHE A CD1 1 
ATOM   3655  C CD2 . PHE A 1 516 ? 125.677 137.652 131.384 1.00 39.99  ?  505 PHE A CD2 1 
ATOM   3656  C CE1 . PHE A 1 516 ? 126.120 135.018 132.008 1.00 39.99  ?  505 PHE A CE1 1 
ATOM   3657  C CE2 . PHE A 1 516 ? 125.452 137.201 132.662 1.00 39.99  ?  505 PHE A CE2 1 
ATOM   3658  C CZ  . PHE A 1 516 ? 125.675 135.884 132.974 1.00 39.99  ?  505 PHE A CZ  1 
ATOM   3659  N N   . PRO A 1 517 ? 128.924 137.198 126.307 1.00 43.24  ?  506 PRO A N   1 
ATOM   3660  C CA  . PRO A 1 517 ? 129.255 137.926 125.077 1.00 43.24  ?  506 PRO A CA  1 
ATOM   3661  C C   . PRO A 1 517 ? 128.093 137.925 124.097 1.00 43.24  ?  506 PRO A C   1 
ATOM   3662  O O   . PRO A 1 517 ? 127.237 137.042 124.119 1.00 43.24  ?  506 PRO A O   1 
ATOM   3663  C CB  . PRO A 1 517 ? 130.458 137.156 124.519 1.00 43.24  ?  506 PRO A CB  1 
ATOM   3664  C CG  . PRO A 1 517 ? 130.930 136.300 125.628 1.00 43.24  ?  506 PRO A CG  1 
ATOM   3665  C CD  . PRO A 1 517 ? 129.748 135.991 126.464 1.00 43.24  ?  506 PRO A CD  1 
ATOM   3666  N N   . LYS A 1 518 ? 127.974 138.897 123.290 1.00 46.75  ?  507 LYS A N   1 
ATOM   3667  C CA  . LYS A 1 518 ? 126.916 138.934 122.306 1.00 46.75  ?  507 LYS A CA  1 
ATOM   3668  C C   . LYS A 1 518 ? 127.353 138.112 121.114 1.00 46.75  ?  507 LYS A C   1 
ATOM   3669  O O   . LYS A 1 518 ? 127.718 138.660 120.079 1.00 46.75  ?  507 LYS A O   1 
ATOM   3670  C CB  . LYS A 1 518 ? 126.605 140.373 121.919 1.00 46.75  ?  507 LYS A CB  1 
ATOM   3671  C CG  . LYS A 1 518 ? 126.121 141.227 123.077 1.00 46.75  ?  507 LYS A CG  1 
ATOM   3672  C CD  . LYS A 1 518 ? 124.889 140.617 123.725 1.00 46.75  ?  507 LYS A CD  1 
ATOM   3673  C CE  . LYS A 1 518 ? 124.306 141.536 124.785 1.00 46.75  ?  507 LYS A CE  1 
ATOM   3674  N NZ  . LYS A 1 518 ? 125.281 141.839 125.869 1.00 46.75  1  507 LYS A NZ  1 
ATOM   3675  N N   . CYS A 1 519 ? 127.411 136.842 121.247 1.00 45.49  ?  508 CYS A N   1 
ATOM   3676  C CA  . CYS A 1 519 ? 127.698 135.882 120.196 1.00 45.49  ?  508 CYS A CA  1 
ATOM   3677  C C   . CYS A 1 519 ? 126.638 135.966 119.104 1.00 45.49  ?  508 CYS A C   1 
ATOM   3678  O O   . CYS A 1 519 ? 125.438 136.045 119.372 1.00 45.49  ?  508 CYS A O   1 
ATOM   3679  C CB  . CYS A 1 519 ? 127.750 134.470 120.768 1.00 45.49  ?  508 CYS A CB  1 
ATOM   3680  S SG  . CYS A 1 519 ? 128.672 134.283 122.301 1.00 45.49  ?  508 CYS A SG  1 
ATOM   3681  N N   . SER A 1 520 ? 127.092 135.940 117.853 1.00 43.51  ?  509 SER A N   1 
ATOM   3682  C CA  . SER A 1 520 ? 126.190 136.202 116.743 1.00 43.51  ?  509 SER A CA  1 
ATOM   3683  C C   . SER A 1 520 ? 126.491 135.269 115.581 1.00 43.51  ?  509 SER A C   1 
ATOM   3684  O O   . SER A 1 520 ? 127.538 134.625 115.523 1.00 43.51  ?  509 SER A O   1 
ATOM   3685  C CB  . SER A 1 520 ? 126.280 137.661 116.284 1.00 43.51  ?  509 SER A CB  1 
ATOM   3686  O OG  . SER A 1 520 ? 127.604 138.011 115.932 1.00 43.51  ?  509 SER A OG  1 
ATOM   3687  N N   . THR A 1 521 ? 125.531 135.183 114.670 1.00 44.09  ?  510 THR A N   1 
ATOM   3688  C CA  . THR A 1 521 ? 125.671 134.441 113.428 1.00 44.09  ?  510 THR A CA  1 
ATOM   3689  C C   . THR A 1 521 ? 125.896 135.426 112.291 1.00 44.09  ?  510 THR A C   1 
ATOM   3690  O O   . THR A 1 521 ? 125.230 136.459 112.215 1.00 44.09  ?  510 THR A O   1 
ATOM   3691  C CB  . THR A 1 521 ? 124.426 133.595 113.158 1.00 44.09  ?  510 THR A CB  1 
ATOM   3692  O OG1 . THR A 1 521 ? 124.253 132.649 114.219 1.00 44.09  ?  510 THR A OG1 1 
ATOM   3693  C CG2 . THR A 1 521 ? 124.550 132.848 111.848 1.00 44.09  ?  510 THR A CG2 1 
ATOM   3694  N N   . LEU A 1 522 ? 126.846 135.112 111.420 1.00 42.13  ?  511 LEU A N   1 
ATOM   3695  C CA  . LEU A 1 522 ? 127.243 135.999 110.342 1.00 42.13  ?  511 LEU A CA  1 
ATOM   3696  C C   . LEU A 1 522 ? 126.669 135.529 109.015 1.00 42.13  ?  511 LEU A C   1 
ATOM   3697  O O   . LEU A 1 522 ? 126.199 134.400 108.875 1.00 42.13  ?  511 LEU A O   1 
ATOM   3698  C CB  . LEU A 1 522 ? 128.767 136.088 110.236 1.00 42.13  ?  511 LEU A CB  1 
ATOM   3699  C CG  . LEU A 1 522 ? 129.558 136.289 111.525 1.00 42.13  ?  511 LEU A CG  1 
ATOM   3700  C CD1 . LEU A 1 522 ? 131.014 136.435 111.194 1.00 42.13  ?  511 LEU A CD1 1 
ATOM   3701  C CD2 . LEU A 1 522 ? 129.065 137.496 112.279 1.00 42.13  ?  511 LEU A CD2 1 
ATOM   3702  N N   . ALA A 1 523 ? 126.656 136.421 108.049 1.00 47.78  ?  512 ALA A N   1 
ATOM   3703  C CA  . ALA A 1 523 ? 126.186 136.054 106.738 1.00 47.78  ?  512 ALA A CA  1 
ATOM   3704  C C   . ALA A 1 523 ? 126.999 136.874 105.773 1.00 47.78  ?  512 ALA A C   1 
ATOM   3705  O O   . ALA A 1 523 ? 127.596 137.870 106.158 1.00 47.78  ?  512 ALA A O   1 
ATOM   3706  C CB  . ALA A 1 523 ? 124.700 136.331 106.600 1.00 47.78  ?  512 ALA A CB  1 
ATOM   3707  N N   . ASN A 1 524 ? 127.050 136.452 104.524 1.00 50.19  ?  513 ASN A N   1 
ATOM   3708  C CA  . ASN A 1 524 ? 127.751 137.224 103.529 1.00 50.19  ?  513 ASN A CA  1 
ATOM   3709  C C   . ASN A 1 524 ? 126.898 138.415 103.144 1.00 50.19  ?  513 ASN A C   1 
ATOM   3710  O O   . ASN A 1 524 ? 125.677 138.333 103.173 1.00 50.19  ?  513 ASN A O   1 
ATOM   3711  C CB  . ASN A 1 524 ? 128.059 136.367 102.305 1.00 50.19  ?  513 ASN A CB  1 
ATOM   3712  C CG  . ASN A 1 524 ? 129.278 136.844 101.554 1.00 50.19  ?  513 ASN A CG  1 
ATOM   3713  O OD1 . ASN A 1 524 ? 130.183 137.435 102.134 1.00 50.19  ?  513 ASN A OD1 1 
ATOM   3714  N ND2 . ASN A 1 524 ? 129.317 136.574 100.259 1.00 50.19  ?  513 ASN A ND2 1 
ATOM   3715  N N   . ILE A 1 525 ? 127.531 139.527 102.791 1.00 53.18  ?  514 ILE A N   1 
ATOM   3716  C CA  . ILE A 1 525 ? 126.786 140.696 102.335 1.00 53.18  ?  514 ILE A CA  1 
ATOM   3717  C C   . ILE A 1 525 ? 127.477 141.386 101.157 1.00 53.18  ?  514 ILE A C   1 
ATOM   3718  O O   . ILE A 1 525 ? 128.485 142.061 101.342 1.00 53.18  ?  514 ILE A O   1 
ATOM   3719  C CB  . ILE A 1 525 ? 126.542 141.686 103.497 1.00 53.18  ?  514 ILE A CB  1 
ATOM   3720  C CG1 . ILE A 1 525 ? 125.928 142.986 102.975 1.00 53.18  ?  514 ILE A CG1 1 
ATOM   3721  C CG2 . ILE A 1 525 ? 127.832 141.950 104.262 1.00 53.18  ?  514 ILE A CG2 1 
ATOM   3722  C CD1 . ILE A 1 525 ? 125.462 143.918 104.069 1.00 53.18  ?  514 ILE A CD1 1 
ATOM   3723  N N   . GLY A 1 526 ? 126.951 141.212 99.946  1.00 57.42  ?  515 GLY A N   1 
ATOM   3724  C CA  . GLY A 1 526 ? 127.544 141.820 98.759  1.00 57.42  ?  515 GLY A CA  1 
ATOM   3725  C C   . GLY A 1 526 ? 128.260 140.837 97.862  1.00 57.42  ?  515 GLY A C   1 
ATOM   3726  O O   . GLY A 1 526 ? 129.123 141.243 97.092  1.00 57.42  ?  515 GLY A O   1 
ATOM   3727  N N   . ARG A 1 527 ? 127.908 139.566 97.927  1.00 56.99  ?  516 ARG A N   1 
ATOM   3728  C CA  . ARG A 1 527 ? 128.555 138.494 97.173  1.00 56.99  ?  516 ARG A CA  1 
ATOM   3729  C C   . ARG A 1 527 ? 130.059 138.728 97.065  1.00 56.99  ?  516 ARG A C   1 
ATOM   3730  O O   . ARG A 1 527 ? 130.662 138.568 96.004  1.00 56.99  ?  516 ARG A O   1 
ATOM   3731  C CB  . ARG A 1 527 ? 127.925 138.331 95.791  1.00 56.99  ?  516 ARG A CB  1 
ATOM   3732  C CG  . ARG A 1 527 ? 126.468 137.909 95.828  1.00 56.99  ?  516 ARG A CG  1 
ATOM   3733  C CD  . ARG A 1 527 ? 126.329 136.466 96.278  1.00 56.99  ?  516 ARG A CD  1 
ATOM   3734  N NE  . ARG A 1 527 ? 124.933 136.051 96.349  1.00 56.99  ?  516 ARG A NE  1 
ATOM   3735  C CZ  . ARG A 1 527 ? 124.505 134.828 96.065  1.00 56.99  ?  516 ARG A CZ  1 
ATOM   3736  N NH1 . ARG A 1 527 ? 125.366 133.896 95.683  1.00 56.99  1  516 ARG A NH1 1 
ATOM   3737  N NH2 . ARG A 1 527 ? 123.215 134.536 96.156  1.00 56.99  ?  516 ARG A NH2 1 
ATOM   3738  N N   . THR A 1 528 ? 130.666 139.104 98.183  1.00 52.00  ?  517 THR A N   1 
ATOM   3739  C CA  . THR A 1 528 ? 132.101 139.358 98.269  1.00 52.00  ?  517 THR A CA  1 
ATOM   3740  C C   . THR A 1 528 ? 132.576 138.774 99.593  1.00 52.00  ?  517 THR A C   1 
ATOM   3741  O O   . THR A 1 528 ? 131.903 137.933 100.199 1.00 52.00  ?  517 THR A O   1 
ATOM   3742  C CB  . THR A 1 528 ? 132.414 140.854 98.129  1.00 52.00  ?  517 THR A CB  1 
ATOM   3743  O OG1 . THR A 1 528 ? 131.436 141.623 98.840  1.00 52.00  ?  517 THR A OG1 1 
ATOM   3744  C CG2 . THR A 1 528 ? 132.412 141.262 96.665  1.00 52.00  ?  517 THR A CG2 1 
ATOM   3745  N N   . ASN A 1 529 ? 133.746 139.205 100.059 1.00 47.33  ?  518 ASN A N   1 
ATOM   3746  C CA  . ASN A 1 529 ? 134.355 138.637 101.254 1.00 47.33  ?  518 ASN A CA  1 
ATOM   3747  C C   . ASN A 1 529 ? 133.993 139.389 102.530 1.00 47.33  ?  518 ASN A C   1 
ATOM   3748  O O   . ASN A 1 529 ? 134.780 139.385 103.482 1.00 47.33  ?  518 ASN A O   1 
ATOM   3749  C CB  . ASN A 1 529 ? 135.873 138.573 101.087 1.00 47.33  ?  518 ASN A CB  1 
ATOM   3750  C CG  . ASN A 1 529 ? 136.473 139.896 100.675 1.00 47.33  ?  518 ASN A CG  1 
ATOM   3751  O OD1 . ASN A 1 529 ? 135.766 140.875 100.478 1.00 47.33  ?  518 ASN A OD1 1 
ATOM   3752  N ND2 . ASN A 1 529 ? 137.787 139.927 100.536 1.00 47.33  ?  518 ASN A ND2 1 
ATOM   3753  N N   . ILE A 1 530 ? 132.826 140.023 102.585 1.00 46.89  ?  519 ILE A N   1 
ATOM   3754  C CA  . ILE A 1 530 ? 132.376 140.753 103.765 1.00 46.89  ?  519 ILE A CA  1 
ATOM   3755  C C   . ILE A 1 530 ? 131.295 139.933 104.449 1.00 46.89  ?  519 ILE A C   1 
ATOM   3756  O O   . ILE A 1 530 ? 130.270 139.616 103.838 1.00 46.89  ?  519 ILE A O   1 
ATOM   3757  C CB  . ILE A 1 530 ? 131.855 142.152 103.409 1.00 46.89  ?  519 ILE A CB  1 
ATOM   3758  C CG1 . ILE A 1 530 ? 132.844 142.882 102.511 1.00 46.89  ?  519 ILE A CG1 1 
ATOM   3759  C CG2 . ILE A 1 530 ? 131.590 142.954 104.667 1.00 46.89  ?  519 ILE A CG2 1 
ATOM   3760  C CD1 . ILE A 1 530 ? 132.306 144.158 101.951 1.00 46.89  ?  519 ILE A CD1 1 
ATOM   3761  N N   . TYR A 1 531 ? 131.514 139.603 105.720 1.00 44.78  ?  520 TYR A N   1 
ATOM   3762  C CA  . TYR A 1 531 ? 130.579 138.810 106.511 1.00 44.78  ?  520 TYR A CA  1 
ATOM   3763  C C   . TYR A 1 531 ? 130.233 139.598 107.765 1.00 44.78  ?  520 TYR A C   1 
ATOM   3764  O O   . TYR A 1 531 ? 131.117 139.909 108.569 1.00 44.78  ?  520 TYR A O   1 
ATOM   3765  C CB  . TYR A 1 531 ? 131.169 137.443 106.863 1.00 44.78  ?  520 TYR A CB  1 
ATOM   3766  C CG  . TYR A 1 531 ? 131.366 136.554 105.663 1.00 44.78  ?  520 TYR A CG  1 
ATOM   3767  C CD1 . TYR A 1 531 ? 132.483 136.678 104.863 1.00 44.78  ?  520 TYR A CD1 1 
ATOM   3768  C CD2 . TYR A 1 531 ? 130.422 135.607 105.317 1.00 44.78  ?  520 TYR A CD2 1 
ATOM   3769  C CE1 . TYR A 1 531 ? 132.659 135.884 103.762 1.00 44.78  ?  520 TYR A CE1 1 
ATOM   3770  C CE2 . TYR A 1 531 ? 130.594 134.808 104.217 1.00 44.78  ?  520 TYR A CE2 1 
ATOM   3771  C CZ  . TYR A 1 531 ? 131.717 134.952 103.444 1.00 44.78  ?  520 TYR A CZ  1 
ATOM   3772  O OH  . TYR A 1 531 ? 131.896 134.160 102.341 1.00 44.78  ?  520 TYR A OH  1 
ATOM   3773  N N   . LYS A 1 532 ? 128.957 139.918 107.934 1.00 48.70  ?  521 LYS A N   1 
ATOM   3774  C CA  . LYS A 1 532 ? 128.491 140.715 109.060 1.00 48.70  ?  521 LYS A CA  1 
ATOM   3775  C C   . LYS A 1 532 ? 127.293 140.038 109.712 1.00 48.70  ?  521 LYS A C   1 
ATOM   3776  O O   . LYS A 1 532 ? 126.789 139.029 109.228 1.00 48.70  ?  521 LYS A O   1 
ATOM   3777  C CB  . LYS A 1 532 ? 128.142 142.138 108.618 1.00 48.70  ?  521 LYS A CB  1 
ATOM   3778  C CG  . LYS A 1 532 ? 129.279 142.868 107.932 1.00 48.70  ?  521 LYS A CG  1 
ATOM   3779  C CD  . LYS A 1 532 ? 129.564 144.199 108.578 1.00 48.70  ?  521 LYS A CD  1 
ATOM   3780  C CE  . LYS A 1 532 ? 130.990 144.623 108.324 1.00 48.70  ?  521 LYS A CE  1 
ATOM   3781  N NZ  . LYS A 1 532 ? 131.950 143.831 109.134 1.00 48.70  1  521 LYS A NZ  1 
ATOM   3782  N N   . ASN A 1 533 ? 126.836 140.622 110.818 1.00 50.77  ?  522 ASN A N   1 
ATOM   3783  C CA  . ASN A 1 533 ? 125.772 140.031 111.619 1.00 50.77  ?  522 ASN A CA  1 
ATOM   3784  C C   . ASN A 1 533 ? 124.552 139.712 110.768 1.00 50.77  ?  522 ASN A C   1 
ATOM   3785  O O   . ASN A 1 533 ? 124.051 140.563 110.034 1.00 50.77  ?  522 ASN A O   1 
ATOM   3786  C CB  . ASN A 1 533 ? 125.385 140.982 112.748 1.00 50.77  ?  522 ASN A CB  1 
ATOM   3787  C CG  . ASN A 1 533 ? 124.760 140.271 113.918 1.00 50.77  ?  522 ASN A CG  1 
ATOM   3788  O OD1 . ASN A 1 533 ? 124.055 139.281 113.753 1.00 50.77  ?  522 ASN A OD1 1 
ATOM   3789  N ND2 . ASN A 1 533 ? 125.009 140.775 115.114 1.00 50.77  ?  522 ASN A ND2 1 
ATOM   3790  N N   . LYS A 1 534 ? 124.066 138.476 110.890 1.00 53.54  ?  523 LYS A N   1 
ATOM   3791  C CA  . LYS A 1 534 ? 122.950 138.003 110.080 1.00 53.54  ?  523 LYS A CA  1 
ATOM   3792  C C   . LYS A 1 534 ? 121.677 138.802 110.319 1.00 53.54  ?  523 LYS A C   1 
ATOM   3793  O O   . LYS A 1 534 ? 120.785 138.801 109.464 1.00 53.54  ?  523 LYS A O   1 
ATOM   3794  C CB  . LYS A 1 534 ? 122.711 136.525 110.379 1.00 53.54  ?  523 LYS A CB  1 
ATOM   3795  C CG  . LYS A 1 534 ? 121.722 135.822 109.494 1.00 53.54  ?  523 LYS A CG  1 
ATOM   3796  C CD  . LYS A 1 534 ? 121.309 134.513 110.133 1.00 53.54  ?  523 LYS A CD  1 
ATOM   3797  C CE  . LYS A 1 534 ? 120.104 133.910 109.443 1.00 53.54  ?  523 LYS A CE  1 
ATOM   3798  N NZ  . LYS A 1 534 ? 119.727 132.608 110.054 1.00 53.54  1  523 LYS A NZ  1 
ATOM   3799  N N   . LYS A 1 535 ? 121.577 139.488 111.453 1.00 60.93  ?  524 LYS A N   1 
ATOM   3800  C CA  . LYS A 1 535 ? 120.379 140.218 111.832 1.00 60.93  ?  524 LYS A CA  1 
ATOM   3801  C C   . LYS A 1 535 ? 120.483 141.714 111.590 1.00 60.93  ?  524 LYS A C   1 
ATOM   3802  O O   . LYS A 1 535 ? 119.601 142.457 112.026 1.00 60.93  ?  524 LYS A O   1 
ATOM   3803  C CB  . LYS A 1 535 ? 120.070 139.971 113.309 1.00 60.93  ?  524 LYS A CB  1 
ATOM   3804  C CG  . LYS A 1 535 ? 119.829 138.522 113.657 1.00 60.93  ?  524 LYS A CG  1 
ATOM   3805  C CD  . LYS A 1 535 ? 119.110 138.395 114.982 1.00 60.93  ?  524 LYS A CD  1 
ATOM   3806  C CE  . LYS A 1 535 ? 119.879 139.089 116.086 1.00 60.93  ?  524 LYS A CE  1 
ATOM   3807  N NZ  . LYS A 1 535 ? 119.385 138.684 117.427 1.00 60.93  1  524 LYS A NZ  1 
ATOM   3808  N N   . ASP A 1 536 ? 121.525 142.177 110.905 1.00 61.44  ?  525 ASP A N   1 
ATOM   3809  C CA  . ASP A 1 536 ? 121.817 143.601 110.845 1.00 61.44  ?  525 ASP A CA  1 
ATOM   3810  C C   . ASP A 1 536 ? 121.485 144.250 109.511 1.00 61.44  ?  525 ASP A C   1 
ATOM   3811  O O   . ASP A 1 536 ? 121.122 145.427 109.494 1.00 61.44  ?  525 ASP A O   1 
ATOM   3812  C CB  . ASP A 1 536 ? 123.291 143.849 111.160 1.00 61.44  ?  525 ASP A CB  1 
ATOM   3813  C CG  . ASP A 1 536 ? 123.546 144.021 112.637 1.00 61.44  ?  525 ASP A CG  1 
ATOM   3814  O OD1 . ASP A 1 536 ? 122.613 143.803 113.431 1.00 61.44  ?  525 ASP A OD1 1 
ATOM   3815  O OD2 . ASP A 1 536 ? 124.681 144.379 113.009 1.00 61.44  -1 525 ASP A OD2 1 
ATOM   3816  N N   . TYR A 1 537 ? 121.592 143.537 108.397 1.00 60.65  ?  526 TYR A N   1 
ATOM   3817  C CA  . TYR A 1 537 ? 121.403 144.144 107.091 1.00 60.65  ?  526 TYR A CA  1 
ATOM   3818  C C   . TYR A 1 537 ? 120.354 143.375 106.304 1.00 60.65  ?  526 TYR A C   1 
ATOM   3819  O O   . TYR A 1 537 ? 119.954 142.270 106.672 1.00 60.65  ?  526 TYR A O   1 
ATOM   3820  C CB  . TYR A 1 537 ? 122.713 144.201 106.291 1.00 60.65  ?  526 TYR A CB  1 
ATOM   3821  C CG  . TYR A 1 537 ? 123.840 144.916 106.999 1.00 60.65  ?  526 TYR A CG  1 
ATOM   3822  C CD1 . TYR A 1 537 ? 124.165 146.223 106.679 1.00 60.65  ?  526 TYR A CD1 1 
ATOM   3823  C CD2 . TYR A 1 537 ? 124.583 144.282 107.981 1.00 60.65  ?  526 TYR A CD2 1 
ATOM   3824  C CE1 . TYR A 1 537 ? 125.187 146.879 107.324 1.00 60.65  ?  526 TYR A CE1 1 
ATOM   3825  C CE2 . TYR A 1 537 ? 125.603 144.930 108.631 1.00 60.65  ?  526 TYR A CE2 1 
ATOM   3826  C CZ  . TYR A 1 537 ? 125.902 146.225 108.297 1.00 60.65  ?  526 TYR A CZ  1 
ATOM   3827  O OH  . TYR A 1 537 ? 126.925 146.873 108.946 1.00 60.65  ?  526 TYR A OH  1 
ATOM   3828  N N   . TYR A 1 538 ? 119.907 143.984 105.211 1.00 67.07  ?  527 TYR A N   1 
ATOM   3829  C CA  . TYR A 1 538 ? 119.005 143.330 104.281 1.00 67.07  ?  527 TYR A CA  1 
ATOM   3830  C C   . TYR A 1 538 ? 119.793 142.673 103.153 1.00 67.07  ?  527 TYR A C   1 
ATOM   3831  O O   . TYR A 1 538 ? 120.948 143.015 102.886 1.00 67.07  ?  527 TYR A O   1 
ATOM   3832  C CB  . TYR A 1 538 ? 118.013 144.331 103.687 1.00 67.07  ?  527 TYR A CB  1 
ATOM   3833  C CG  . TYR A 1 538 ? 116.967 144.840 104.649 1.00 67.07  ?  527 TYR A CG  1 
ATOM   3834  C CD1 . TYR A 1 538 ? 116.035 143.981 105.212 1.00 67.07  ?  527 TYR A CD1 1 
ATOM   3835  C CD2 . TYR A 1 538 ? 116.901 146.185 104.980 1.00 67.07  ?  527 TYR A CD2 1 
ATOM   3836  C CE1 . TYR A 1 538 ? 115.075 144.445 106.084 1.00 67.07  ?  527 TYR A CE1 1 
ATOM   3837  C CE2 . TYR A 1 538 ? 115.946 146.656 105.853 1.00 67.07  ?  527 TYR A CE2 1 
ATOM   3838  C CZ  . TYR A 1 538 ? 115.035 145.783 106.400 1.00 67.07  ?  527 TYR A CZ  1 
ATOM   3839  O OH  . TYR A 1 538 ? 114.080 146.253 107.271 1.00 67.07  ?  527 TYR A OH  1 
ATOM   3840  N N   . ASP A 1 539 ? 119.149 141.714 102.490 1.00 66.14  ?  528 ASP A N   1 
ATOM   3841  C CA  . ASP A 1 539 ? 119.692 141.072 101.294 1.00 66.14  ?  528 ASP A CA  1 
ATOM   3842  C C   . ASP A 1 539 ? 120.989 140.319 101.580 1.00 66.14  ?  528 ASP A C   1 
ATOM   3843  O O   . ASP A 1 539 ? 121.868 140.232 100.722 1.00 66.14  ?  528 ASP A O   1 
ATOM   3844  C CB  . ASP A 1 539 ? 119.908 142.089 100.170 1.00 66.14  ?  528 ASP A CB  1 
ATOM   3845  C CG  . ASP A 1 539 ? 118.650 142.353 99.374  1.00 66.14  ?  528 ASP A CG  1 
ATOM   3846  O OD1 . ASP A 1 539 ? 117.551 142.007 99.858  1.00 66.14  ?  528 ASP A OD1 1 
ATOM   3847  O OD2 . ASP A 1 539 ? 118.757 142.911 98.263  1.00 66.14  -1 528 ASP A OD2 1 
ATOM   3848  N N   . MET A 1 540 ? 121.122 139.767 102.780 1.00 58.24  ?  529 MET A N   1 
ATOM   3849  C CA  . MET A 1 540 ? 122.272 138.942 103.108 1.00 58.24  ?  529 MET A CA  1 
ATOM   3850  C C   . MET A 1 540 ? 122.075 137.529 102.571 1.00 58.24  ?  529 MET A C   1 
ATOM   3851  O O   . MET A 1 540 ? 121.010 137.180 102.056 1.00 58.24  ?  529 MET A O   1 
ATOM   3852  C CB  . MET A 1 540 ? 122.505 138.917 104.615 1.00 58.24  ?  529 MET A CB  1 
ATOM   3853  C CG  . MET A 1 540 ? 122.618 140.298 105.219 1.00 58.24  ?  529 MET A CG  1 
ATOM   3854  S SD  . MET A 1 540 ? 122.891 140.264 106.990 1.00 58.24  ?  529 MET A SD  1 
ATOM   3855  C CE  . MET A 1 540 ? 124.653 140.487 107.029 1.00 58.24  ?  529 MET A CE  1 
ATOM   3856  N N   . TYR A 1 541 ? 123.118 136.713 102.690 1.00 55.73  ?  530 TYR A N   1 
ATOM   3857  C CA  . TYR A 1 541 ? 123.139 135.404 102.042 1.00 55.73  ?  530 TYR A CA  1 
ATOM   3858  C C   . TYR A 1 541 ? 123.859 134.404 102.933 1.00 55.73  ?  530 TYR A C   1 
ATOM   3859  O O   . TYR A 1 541 ? 125.012 134.623 103.314 1.00 55.73  ?  530 TYR A O   1 
ATOM   3860  C CB  . TYR A 1 541 ? 123.809 135.489 100.671 1.00 55.73  ?  530 TYR A CB  1 
ATOM   3861  C CG  . TYR A 1 541 ? 124.184 134.156 100.079 1.00 55.73  ?  530 TYR A CG  1 
ATOM   3862  C CD1 . TYR A 1 541 ? 125.504 133.737 100.047 1.00 55.73  ?  530 TYR A CD1 1 
ATOM   3863  C CD2 . TYR A 1 541 ? 123.219 133.319 99.540  1.00 55.73  ?  530 TYR A CD2 1 
ATOM   3864  C CE1 . TYR A 1 541 ? 125.854 132.520 99.504  1.00 55.73  ?  530 TYR A CE1 1 
ATOM   3865  C CE2 . TYR A 1 541 ? 123.560 132.098 98.995  1.00 55.73  ?  530 TYR A CE2 1 
ATOM   3866  C CZ  . TYR A 1 541 ? 124.879 131.706 98.979  1.00 55.73  ?  530 TYR A CZ  1 
ATOM   3867  O OH  . TYR A 1 541 ? 125.226 130.492 98.436  1.00 55.73  ?  530 TYR A OH  1 
ATOM   3868  N N   . GLU A 1 542 ? 123.175 133.311 103.267 1.00 55.62  ?  531 GLU A N   1 
ATOM   3869  C CA  . GLU A 1 542 ? 123.774 132.207 103.998 1.00 55.62  ?  531 GLU A CA  1 
ATOM   3870  C C   . GLU A 1 542 ? 124.021 131.062 103.035 1.00 55.62  ?  531 GLU A C   1 
ATOM   3871  O O   . GLU A 1 542 ? 123.051 130.528 102.476 1.00 55.62  ?  531 GLU A O   1 
ATOM   3872  C CB  . GLU A 1 542 ? 122.851 131.747 105.122 1.00 55.62  ?  531 GLU A CB  1 
ATOM   3873  C CG  . GLU A 1 542 ? 122.798 132.655 106.330 1.00 55.62  ?  531 GLU A CG  1 
ATOM   3874  C CD  . GLU A 1 542 ? 123.613 132.128 107.485 1.00 55.62  ?  531 GLU A CD  1 
ATOM   3875  O OE1 . GLU A 1 542 ? 123.176 132.287 108.642 1.00 55.62  ?  531 GLU A OE1 1 
ATOM   3876  O OE2 . GLU A 1 542 ? 124.692 131.554 107.238 1.00 55.62  -1 531 GLU A OE2 1 
ATOM   3877  N N   . PRO A 1 543 ? 125.267 130.659 102.789 1.00 54.79  ?  532 PRO A N   1 
ATOM   3878  C CA  . PRO A 1 543 ? 125.497 129.483 101.946 1.00 54.79  ?  532 PRO A CA  1 
ATOM   3879  C C   . PRO A 1 543 ? 124.816 128.258 102.535 1.00 54.79  ?  532 PRO A C   1 
ATOM   3880  O O   . PRO A 1 543 ? 124.790 128.058 103.749 1.00 54.79  ?  532 PRO A O   1 
ATOM   3881  C CB  . PRO A 1 543 ? 127.024 129.336 101.934 1.00 54.79  ?  532 PRO A CB  1 
ATOM   3882  C CG  . PRO A 1 543 ? 127.534 130.260 102.983 1.00 54.79  ?  532 PRO A CG  1 
ATOM   3883  C CD  . PRO A 1 543 ? 126.522 131.327 103.168 1.00 54.79  ?  532 PRO A CD  1 
ATOM   3884  N N   . GLU A 1 544 ? 124.247 127.442 101.653 1.00 56.95  ?  533 GLU A N   1 
ATOM   3885  C CA  . GLU A 1 544 ? 123.375 126.353 102.077 1.00 56.95  ?  533 GLU A CA  1 
ATOM   3886  C C   . GLU A 1 544 ? 124.162 125.314 102.865 1.00 56.95  ?  533 GLU A C   1 
ATOM   3887  O O   . GLU A 1 544 ? 125.024 124.626 102.313 1.00 56.95  ?  533 GLU A O   1 
ATOM   3888  C CB  . GLU A 1 544 ? 122.709 125.714 100.861 1.00 56.95  ?  533 GLU A CB  1 
ATOM   3889  C CG  . GLU A 1 544 ? 121.722 124.615 101.205 1.00 56.95  ?  533 GLU A CG  1 
ATOM   3890  C CD  . GLU A 1 544 ? 120.511 125.135 101.954 1.00 56.95  ?  533 GLU A CD  1 
ATOM   3891  O OE1 . GLU A 1 544 ? 120.147 126.312 101.757 1.00 56.95  ?  533 GLU A OE1 1 
ATOM   3892  O OE2 . GLU A 1 544 ? 119.926 124.365 102.745 1.00 56.95  -1 533 GLU A OE2 1 
ATOM   3893  N N   . GLY A 1 545 ? 123.862 125.202 104.155 1.00 52.42  ?  534 GLY A N   1 
ATOM   3894  C CA  . GLY A 1 545 ? 124.517 124.245 105.016 1.00 52.42  ?  534 GLY A CA  1 
ATOM   3895  C C   . GLY A 1 545 ? 125.637 124.798 105.868 1.00 52.42  ?  534 GLY A C   1 
ATOM   3896  O O   . GLY A 1 545 ? 126.166 124.067 106.708 1.00 52.42  ?  534 GLY A O   1 
ATOM   3897  N N   . VAL A 1 546 ? 126.009 126.060 105.689 1.00 48.77  ?  535 VAL A N   1 
ATOM   3898  C CA  . VAL A 1 546 ? 127.126 126.664 106.398 1.00 48.77  ?  535 VAL A CA  1 
ATOM   3899  C C   . VAL A 1 546 ? 126.587 127.616 107.455 1.00 48.77  ?  535 VAL A C   1 
ATOM   3900  O O   . VAL A 1 546 ? 125.715 128.443 107.175 1.00 48.77  ?  535 VAL A O   1 
ATOM   3901  C CB  . VAL A 1 546 ? 128.075 127.402 105.435 1.00 48.77  ?  535 VAL A CB  1 
ATOM   3902  C CG1 . VAL A 1 546 ? 129.348 127.802 106.145 1.00 48.77  ?  535 VAL A CG1 1 
ATOM   3903  C CG2 . VAL A 1 546 ? 128.387 126.537 104.237 1.00 48.77  ?  535 VAL A CG2 1 
ATOM   3904  N N   . LYS A 1 547 ? 127.101 127.483 108.675 1.00 44.68  ?  536 LYS A N   1 
ATOM   3905  C CA  . LYS A 1 547 ? 126.857 128.432 109.751 1.00 44.68  ?  536 LYS A CA  1 
ATOM   3906  C C   . LYS A 1 547 ? 128.176 129.097 110.106 1.00 44.68  ?  536 LYS A C   1 
ATOM   3907  O O   . LYS A 1 547 ? 129.204 128.423 110.194 1.00 44.68  ?  536 LYS A O   1 
ATOM   3908  C CB  . LYS A 1 547 ? 126.267 127.747 110.985 1.00 44.68  ?  536 LYS A CB  1 
ATOM   3909  C CG  . LYS A 1 547 ? 124.788 127.428 110.890 1.00 44.68  ?  536 LYS A CG  1 
ATOM   3910  C CD  . LYS A 1 547 ? 123.938 128.624 111.227 1.00 44.68  ?  536 LYS A CD  1 
ATOM   3911  C CE  . LYS A 1 547 ? 122.490 128.368 110.874 1.00 44.68  ?  536 LYS A CE  1 
ATOM   3912  N NZ  . LYS A 1 547 ? 121.651 129.570 111.108 1.00 44.68  1  536 LYS A NZ  1 
ATOM   3913  N N   . ILE A 1 548 ? 128.150 130.408 110.298 1.00 40.64  ?  537 ILE A N   1 
ATOM   3914  C CA  . ILE A 1 548 ? 129.319 131.166 110.721 1.00 40.64  ?  537 ILE A CA  1 
ATOM   3915  C C   . ILE A 1 548 ? 128.980 131.790 112.064 1.00 40.64  ?  537 ILE A C   1 
ATOM   3916  O O   . ILE A 1 548 ? 128.064 132.611 112.162 1.00 40.64  ?  537 ILE A O   1 
ATOM   3917  C CB  . ILE A 1 548 ? 129.722 132.228 109.691 1.00 40.64  ?  537 ILE A CB  1 
ATOM   3918  C CG1 . ILE A 1 548 ? 129.719 131.631 108.287 1.00 40.64  ?  537 ILE A CG1 1 
ATOM   3919  C CG2 . ILE A 1 548 ? 131.087 132.799 110.020 1.00 40.64  ?  537 ILE A CG2 1 
ATOM   3920  C CD1 . ILE A 1 548 ? 130.009 132.614 107.212 1.00 40.64  ?  537 ILE A CD1 1 
ATOM   3921  N N   . PHE A 1 549 ? 129.711 131.402 113.098 1.00 39.78  ?  538 PHE A N   1 
ATOM   3922  C CA  . PHE A 1 549 ? 129.441 131.820 114.462 1.00 39.78  ?  538 PHE A CA  1 
ATOM   3923  C C   . PHE A 1 549 ? 130.597 132.671 114.966 1.00 39.78  ?  538 PHE A C   1 
ATOM   3924  O O   . PHE A 1 549 ? 131.761 132.344 114.724 1.00 39.78  ?  538 PHE A O   1 
ATOM   3925  C CB  . PHE A 1 549 ? 129.233 130.599 115.359 1.00 39.78  ?  538 PHE A CB  1 
ATOM   3926  C CG  . PHE A 1 549 ? 128.826 130.935 116.757 1.00 39.78  ?  538 PHE A CG  1 
ATOM   3927  C CD1 . PHE A 1 549 ? 127.562 131.409 117.028 1.00 39.78  ?  538 PHE A CD1 1 
ATOM   3928  C CD2 . PHE A 1 549 ? 129.711 130.771 117.802 1.00 39.78  ?  538 PHE A CD2 1 
ATOM   3929  C CE1 . PHE A 1 549 ? 127.202 131.719 118.303 1.00 39.78  ?  538 PHE A CE1 1 
ATOM   3930  C CE2 . PHE A 1 549 ? 129.347 131.082 119.076 1.00 39.78  ?  538 PHE A CE2 1 
ATOM   3931  C CZ  . PHE A 1 549 ? 128.095 131.547 119.327 1.00 39.78  ?  538 PHE A CZ  1 
ATOM   3932  N N   . ARG A 1 550 ? 130.278 133.758 115.662 1.00 43.67  ?  539 ARG A N   1 
ATOM   3933  C CA  . ARG A 1 550 ? 131.279 134.687 116.166 1.00 43.67  ?  539 ARG A CA  1 
ATOM   3934  C C   . ARG A 1 550 ? 131.040 134.948 117.645 1.00 43.67  ?  539 ARG A C   1 
ATOM   3935  O O   . ARG A 1 550 ? 129.940 135.346 118.042 1.00 43.67  ?  539 ARG A O   1 
ATOM   3936  C CB  . ARG A 1 550 ? 131.247 135.997 115.383 1.00 43.67  ?  539 ARG A CB  1 
ATOM   3937  C CG  . ARG A 1 550 ? 131.815 137.168 116.142 1.00 43.67  ?  539 ARG A CG  1 
ATOM   3938  C CD  . ARG A 1 550 ? 131.911 138.402 115.276 1.00 43.67  ?  539 ARG A CD  1 
ATOM   3939  N NE  . ARG A 1 550 ? 132.642 139.470 115.945 1.00 43.67  ?  539 ARG A NE  1 
ATOM   3940  C CZ  . ARG A 1 550 ? 133.944 139.677 115.804 1.00 43.67  ?  539 ARG A CZ  1 
ATOM   3941  N NH1 . ARG A 1 550 ? 134.534 140.667 116.453 1.00 43.67  1  539 ARG A NH1 1 
ATOM   3942  N NH2 . ARG A 1 550 ? 134.656 138.890 115.016 1.00 43.67  ?  539 ARG A NH2 1 
ATOM   3943  N N   . CYS A 1 551 ? 132.069 134.707 118.458 1.00 46.47  ?  540 CYS A N   1 
ATOM   3944  C CA  . CYS A 1 551 ? 132.114 135.145 119.845 1.00 46.47  ?  540 CYS A CA  1 
ATOM   3945  C C   . CYS A 1 551 ? 133.103 136.295 119.947 1.00 46.47  ?  540 CYS A C   1 
ATOM   3946  O O   . CYS A 1 551 ? 134.293 136.101 119.660 1.00 46.47  ?  540 CYS A O   1 
ATOM   3947  C CB  . CYS A 1 551 ? 132.525 134.005 120.771 1.00 46.47  ?  540 CYS A CB  1 
ATOM   3948  S SG  . CYS A 1 551 ? 132.589 134.455 122.518 1.00 46.47  ?  540 CYS A SG  1 
ATOM   3949  N N   . PRO A 1 552 ? 132.669 137.499 120.314 1.00 45.22  ?  541 PRO A N   1 
ATOM   3950  C CA  . PRO A 1 552 ? 133.543 138.675 120.280 1.00 45.22  ?  541 PRO A CA  1 
ATOM   3951  C C   . PRO A 1 552 ? 134.298 138.929 121.581 1.00 45.22  ?  541 PRO A C   1 
ATOM   3952  O O   . PRO A 1 552 ? 134.349 140.058 122.079 1.00 45.22  ?  541 PRO A O   1 
ATOM   3953  C CB  . PRO A 1 552 ? 132.557 139.805 119.985 1.00 45.22  ?  541 PRO A CB  1 
ATOM   3954  C CG  . PRO A 1 552 ? 131.327 139.372 120.719 1.00 45.22  ?  541 PRO A CG  1 
ATOM   3955  C CD  . PRO A 1 552 ? 131.298 137.861 120.706 1.00 45.22  ?  541 PRO A CD  1 
ATOM   3956  N N   . SER A 1 553 ? 134.825 137.858 122.164 1.00 42.24  ?  542 SER A N   1 
ATOM   3957  C CA  . SER A 1 553 ? 135.555 137.964 123.423 1.00 42.24  ?  542 SER A CA  1 
ATOM   3958  C C   . SER A 1 553 ? 136.471 136.775 123.656 1.00 42.24  ?  542 SER A C   1 
ATOM   3959  O O   . SER A 1 553 ? 136.307 135.734 123.035 1.00 42.24  ?  542 SER A O   1 
ATOM   3960  C CB  . SER A 1 553 ? 134.584 138.076 124.601 1.00 42.24  ?  542 SER A CB  1 
ATOM   3961  O OG  . SER A 1 553 ? 133.933 136.847 124.846 1.00 42.24  ?  542 SER A OG  1 
ATOM   3962  N N   . PRO A 1 554 ? 137.451 136.930 124.552 1.00 42.05  ?  543 PRO A N   1 
ATOM   3963  C CA  . PRO A 1 554 ? 138.284 135.776 124.891 1.00 42.05  ?  543 PRO A CA  1 
ATOM   3964  C C   . PRO A 1 554 ? 137.440 134.724 125.585 1.00 42.05  ?  543 PRO A C   1 
ATOM   3965  O O   . PRO A 1 554 ? 136.558 135.070 126.358 1.00 42.05  ?  543 PRO A O   1 
ATOM   3966  C CB  . PRO A 1 554 ? 139.304 136.350 125.870 1.00 42.05  ?  543 PRO A CB  1 
ATOM   3967  C CG  . PRO A 1 554 ? 139.275 137.824 125.661 1.00 42.05  ?  543 PRO A CG  1 
ATOM   3968  C CD  . PRO A 1 554 ? 137.875 138.151 125.252 1.00 42.05  ?  543 PRO A CD  1 
ATOM   3969  N N   . ILE A 1 555 ? 137.705 133.454 125.317 1.00 42.91  ?  544 ILE A N   1 
ATOM   3970  C CA  . ILE A 1 555 ? 136.920 132.386 125.912 1.00 42.91  ?  544 ILE A CA  1 
ATOM   3971  C C   . ILE A 1 555 ? 137.707 131.700 127.005 1.00 42.91  ?  544 ILE A C   1 
ATOM   3972  O O   . ILE A 1 555 ? 138.788 131.182 126.768 1.00 42.91  ?  544 ILE A O   1 
ATOM   3973  C CB  . ILE A 1 555 ? 136.452 131.367 124.857 1.00 42.91  ?  544 ILE A CB  1 
ATOM   3974  C CG1 . ILE A 1 555 ? 135.842 132.093 123.656 1.00 42.91  ?  544 ILE A CG1 1 
ATOM   3975  C CG2 . ILE A 1 555 ? 135.455 130.391 125.464 1.00 42.91  ?  544 ILE A CG2 1 
ATOM   3976  C CD1 . ILE A 1 555 ? 135.499 131.182 122.501 1.00 42.91  ?  544 ILE A CD1 1 
ATOM   3977  N N   . TYR A 1 556 ? 137.155 131.697 128.209 1.00 40.79  ?  545 TYR A N   1 
ATOM   3978  C CA  . TYR A 1 556 ? 137.835 131.085 129.343 1.00 40.79  ?  545 TYR A CA  1 
ATOM   3979  C C   . TYR A 1 556 ? 136.849 130.414 130.290 1.00 40.79  ?  545 TYR A C   1 
ATOM   3980  O O   . TYR A 1 556 ? 135.714 130.170 129.916 1.00 40.79  ?  545 TYR A O   1 
ATOM   3981  C CB  . TYR A 1 556 ? 138.696 132.125 130.076 1.00 40.79  ?  545 TYR A CB  1 
ATOM   3982  C CG  . TYR A 1 556 ? 137.937 133.321 130.596 1.00 40.79  ?  545 TYR A CG  1 
ATOM   3983  C CD1 . TYR A 1 556 ? 137.363 134.236 129.727 1.00 40.79  ?  545 TYR A CD1 1 
ATOM   3984  C CD2 . TYR A 1 556 ? 137.807 133.541 131.959 1.00 40.79  ?  545 TYR A CD2 1 
ATOM   3985  C CE1 . TYR A 1 556 ? 136.668 135.330 130.200 1.00 40.79  ?  545 TYR A CE1 1 
ATOM   3986  C CE2 . TYR A 1 556 ? 137.118 134.633 132.442 1.00 40.79  ?  545 TYR A CE2 1 
ATOM   3987  C CZ  . TYR A 1 556 ? 136.550 135.524 131.558 1.00 40.79  ?  545 TYR A CZ  1 
ATOM   3988  O OH  . TYR A 1 556 ? 135.862 136.611 132.037 1.00 40.79  ?  545 TYR A OH  1 
ATOM   3989  N N   . PHE A 1 557 ? 137.266 130.142 131.518 1.00 40.52  ?  546 PHE A N   1 
ATOM   3990  C CA  . PHE A 1 557 ? 136.418 129.422 132.480 1.00 40.52  ?  546 PHE A CA  1 
ATOM   3991  C C   . PHE A 1 557 ? 135.045 130.041 132.763 1.00 40.52  ?  546 PHE A C   1 
ATOM   3992  O O   . PHE A 1 557 ? 134.081 129.316 132.972 1.00 40.52  ?  546 PHE A O   1 
ATOM   3993  C CB  . PHE A 1 557 ? 137.181 129.211 133.803 1.00 40.52  ?  546 PHE A CB  1 
ATOM   3994  C CG  . PHE A 1 557 ? 137.466 130.471 134.566 1.00 40.52  ?  546 PHE A CG  1 
ATOM   3995  C CD1 . PHE A 1 557 ? 138.665 131.140 134.400 1.00 40.52  ?  546 PHE A CD1 1 
ATOM   3996  C CD2 . PHE A 1 557 ? 136.551 130.966 135.479 1.00 40.52  ?  546 PHE A CD2 1 
ATOM   3997  C CE1 . PHE A 1 557 ? 138.936 132.292 135.110 1.00 40.52  ?  546 PHE A CE1 1 
ATOM   3998  C CE2 . PHE A 1 557 ? 136.813 132.119 136.189 1.00 40.52  ?  546 PHE A CE2 1 
ATOM   3999  C CZ  . PHE A 1 557 ? 138.008 132.784 136.004 1.00 40.52  ?  546 PHE A CZ  1 
ATOM   4000  N N   . ALA A 1 558 ? 134.949 131.362 132.763 1.00 40.28  ?  547 ALA A N   1 
ATOM   4001  C CA  . ALA A 1 558 ? 133.684 132.012 133.089 1.00 40.28  ?  547 ALA A CA  1 
ATOM   4002  C C   . ALA A 1 558 ? 132.653 132.060 131.949 1.00 40.28  ?  547 ALA A C   1 
ATOM   4003  O O   . ALA A 1 558 ? 131.495 132.369 132.192 1.00 40.28  ?  547 ALA A O   1 
ATOM   4004  C CB  . ALA A 1 558 ? 133.950 133.416 133.619 1.00 40.28  ?  547 ALA A CB  1 
ATOM   4005  N N   . ASN A 1 559 ? 133.056 131.755 130.721 1.00 41.59  ?  548 ASN A N   1 
ATOM   4006  C CA  . ASN A 1 559 ? 132.125 131.879 129.594 1.00 41.59  ?  548 ASN A CA  1 
ATOM   4007  C C   . ASN A 1 559 ? 132.085 130.700 128.609 1.00 41.59  ?  548 ASN A C   1 
ATOM   4008  O O   . ASN A 1 559 ? 131.378 130.768 127.617 1.00 41.59  ?  548 ASN A O   1 
ATOM   4009  C CB  . ASN A 1 559 ? 132.402 133.187 128.835 1.00 41.59  ?  548 ASN A CB  1 
ATOM   4010  C CG  . ASN A 1 559 ? 133.823 133.286 128.322 1.00 41.59  ?  548 ASN A CG  1 
ATOM   4011  O OD1 . ASN A 1 559 ? 134.582 132.323 128.357 1.00 41.59  ?  548 ASN A OD1 1 
ATOM   4012  N ND2 . ASN A 1 559 ? 134.186 134.461 127.833 1.00 41.59  ?  548 ASN A ND2 1 
ATOM   4013  N N   . ILE A 1 560 ? 132.820 129.631 128.880 1.00 42.92  ?  549 ILE A N   1 
ATOM   4014  C CA  . ILE A 1 560 ? 132.832 128.466 127.991 1.00 42.92  ?  549 ILE A CA  1 
ATOM   4015  C C   . ILE A 1 560 ? 131.448 127.815 127.932 1.00 42.92  ?  549 ILE A C   1 
ATOM   4016  O O   . ILE A 1 560 ? 131.057 127.302 126.892 1.00 42.92  ?  549 ILE A O   1 
ATOM   4017  C CB  . ILE A 1 560 ? 133.947 127.449 128.382 1.00 42.92  ?  549 ILE A CB  1 
ATOM   4018  C CG1 . ILE A 1 560 ? 133.967 126.260 127.415 1.00 42.92  ?  549 ILE A CG1 1 
ATOM   4019  C CG2 . ILE A 1 560 ? 133.787 126.993 129.825 1.00 42.92  ?  549 ILE A CG2 1 
ATOM   4020  C CD1 . ILE A 1 560 ? 134.374 126.620 126.003 1.00 42.92  ?  549 ILE A CD1 1 
ATOM   4021  N N   . GLY A 1 561 ? 130.705 127.845 129.028 1.00 42.99  ?  550 GLY A N   1 
ATOM   4022  C CA  . GLY A 1 561 ? 129.351 127.319 129.068 1.00 42.99  ?  550 GLY A CA  1 
ATOM   4023  C C   . GLY A 1 561 ? 128.384 128.173 128.275 1.00 42.99  ?  550 GLY A C   1 
ATOM   4024  O O   . GLY A 1 561 ? 127.560 127.657 127.516 1.00 42.99  ?  550 GLY A O   1 
ATOM   4025  N N   . PHE A 1 562 ? 128.475 129.491 128.440 1.00 41.85  ?  551 PHE A N   1 
ATOM   4026  C CA  . PHE A 1 562 ? 127.658 130.411 127.660 1.00 41.85  ?  551 PHE A CA  1 
ATOM   4027  C C   . PHE A 1 562 ? 127.958 130.286 126.174 1.00 41.85  ?  551 PHE A C   1 
ATOM   4028  O O   . PHE A 1 562 ? 127.042 130.286 125.347 1.00 41.85  ?  551 PHE A O   1 
ATOM   4029  C CB  . PHE A 1 562 ? 127.903 131.838 128.146 1.00 41.85  ?  551 PHE A CB  1 
ATOM   4030  C CG  . PHE A 1 562 ? 126.971 132.855 127.564 1.00 41.85  ?  551 PHE A CG  1 
ATOM   4031  C CD1 . PHE A 1 562 ? 127.308 133.549 126.422 1.00 41.85  ?  551 PHE A CD1 1 
ATOM   4032  C CD2 . PHE A 1 562 ? 125.768 133.134 128.177 1.00 41.85  ?  551 PHE A CD2 1 
ATOM   4033  C CE1 . PHE A 1 562 ? 126.460 134.488 125.896 1.00 41.85  ?  551 PHE A CE1 1 
ATOM   4034  C CE2 . PHE A 1 562 ? 124.919 134.068 127.652 1.00 41.85  ?  551 PHE A CE2 1 
ATOM   4035  C CZ  . PHE A 1 562 ? 125.265 134.747 126.510 1.00 41.85  ?  551 PHE A CZ  1 
ATOM   4036  N N   . PHE A 1 563 ? 129.226 130.079 125.841 1.00 41.07  ?  552 PHE A N   1 
ATOM   4037  C CA  . PHE A 1 563 ? 129.622 129.874 124.453 1.00 41.07  ?  552 PHE A CA  1 
ATOM   4038  C C   . PHE A 1 563 ? 129.011 128.609 123.877 1.00 41.07  ?  552 PHE A C   1 
ATOM   4039  O O   . PHE A 1 563 ? 128.452 128.630 122.788 1.00 41.07  ?  552 PHE A O   1 
ATOM   4040  C CB  . PHE A 1 563 ? 131.146 129.798 124.361 1.00 41.07  ?  552 PHE A CB  1 
ATOM   4041  C CG  . PHE A 1 563 ? 131.656 129.449 122.997 1.00 41.07  ?  552 PHE A CG  1 
ATOM   4042  C CD1 . PHE A 1 563 ? 132.017 128.149 122.689 1.00 41.07  ?  552 PHE A CD1 1 
ATOM   4043  C CD2 . PHE A 1 563 ? 131.771 130.420 122.021 1.00 41.07  ?  552 PHE A CD2 1 
ATOM   4044  C CE1 . PHE A 1 563 ? 132.482 127.825 121.431 1.00 41.07  ?  552 PHE A CE1 1 
ATOM   4045  C CE2 . PHE A 1 563 ? 132.238 130.104 120.762 1.00 41.07  ?  552 PHE A CE2 1 
ATOM   4046  C CZ  . PHE A 1 563 ? 132.595 128.805 120.466 1.00 41.07  ?  552 PHE A CZ  1 
ATOM   4047  N N   . ARG A 1 564 ? 129.120 127.507 124.606 1.00 45.51  ?  553 ARG A N   1 
ATOM   4048  C CA  . ARG A 1 564 ? 128.572 126.241 124.138 1.00 45.51  ?  553 ARG A CA  1 
ATOM   4049  C C   . ARG A 1 564 ? 127.058 126.317 123.974 1.00 45.51  ?  553 ARG A C   1 
ATOM   4050  O O   . ARG A 1 564 ? 126.511 125.772 123.028 1.00 45.51  ?  553 ARG A O   1 
ATOM   4051  C CB  . ARG A 1 564 ? 128.964 125.098 125.079 1.00 45.51  ?  553 ARG A CB  1 
ATOM   4052  C CG  . ARG A 1 564 ? 128.330 123.767 124.715 1.00 45.51  ?  553 ARG A CG  1 
ATOM   4053  C CD  . ARG A 1 564 ? 128.526 122.731 125.807 1.00 45.51  ?  553 ARG A CD  1 
ATOM   4054  N NE  . ARG A 1 564 ? 129.493 121.705 125.431 1.00 45.51  ?  553 ARG A NE  1 
ATOM   4055  C CZ  . ARG A 1 564 ? 130.795 121.770 125.691 1.00 45.51  ?  553 ARG A CZ  1 
ATOM   4056  N NH1 . ARG A 1 564 ? 131.596 120.787 125.309 1.00 45.51  1  553 ARG A NH1 1 
ATOM   4057  N NH2 . ARG A 1 564 ? 131.295 122.818 126.332 1.00 45.51  ?  553 ARG A NH2 1 
ATOM   4058  N N   . ARG A 1 565 ? 126.389 127.017 124.876 1.00 43.42  ?  554 ARG A N   1 
ATOM   4059  C CA  . ARG A 1 565 ? 124.940 127.179 124.781 1.00 43.42  ?  554 ARG A CA  1 
ATOM   4060  C C   . ARG A 1 565 ? 124.501 128.091 123.627 1.00 43.42  ?  554 ARG A C   1 
ATOM   4061  O O   . ARG A 1 565 ? 123.504 127.811 122.979 1.00 43.42  ?  554 ARG A O   1 
ATOM   4062  C CB  . ARG A 1 565 ? 124.367 127.672 126.116 1.00 43.42  ?  554 ARG A CB  1 
ATOM   4063  C CG  . ARG A 1 565 ? 124.360 126.602 127.193 1.00 43.42  ?  554 ARG A CG  1 
ATOM   4064  C CD  . ARG A 1 565 ? 123.714 127.075 128.485 1.00 43.42  ?  554 ARG A CD  1 
ATOM   4065  N NE  . ARG A 1 565 ? 124.604 127.911 129.286 1.00 43.42  ?  554 ARG A NE  1 
ATOM   4066  C CZ  . ARG A 1 565 ? 124.559 129.238 129.318 1.00 43.42  ?  554 ARG A CZ  1 
ATOM   4067  N NH1 . ARG A 1 565 ? 125.411 129.910 130.079 1.00 43.42  1  554 ARG A NH1 1 
ATOM   4068  N NH2 . ARG A 1 565 ? 123.659 129.893 128.598 1.00 43.42  ?  554 ARG A NH2 1 
ATOM   4069  N N   . LYS A 1 566 ? 125.246 129.156 123.351 1.00 43.44  ?  555 LYS A N   1 
ATOM   4070  C CA  . LYS A 1 566 ? 124.918 130.036 122.235 1.00 43.44  ?  555 LYS A CA  1 
ATOM   4071  C C   . LYS A 1 566 ? 125.235 129.383 120.897 1.00 43.44  ?  555 LYS A C   1 
ATOM   4072  O O   . LYS A 1 566 ? 124.508 129.579 119.921 1.00 43.44  ?  555 LYS A O   1 
ATOM   4073  C CB  . LYS A 1 566 ? 125.664 131.359 122.374 1.00 43.44  ?  555 LYS A CB  1 
ATOM   4074  C CG  . LYS A 1 566 ? 125.267 132.160 123.585 1.00 43.44  ?  555 LYS A CG  1 
ATOM   4075  C CD  . LYS A 1 566 ? 123.966 132.888 123.363 1.00 43.44  ?  555 LYS A CD  1 
ATOM   4076  C CE  . LYS A 1 566 ? 122.921 132.438 124.359 1.00 43.44  ?  555 LYS A CE  1 
ATOM   4077  N NZ  . LYS A 1 566 ? 121.564 132.883 123.961 1.00 43.44  1  555 LYS A NZ  1 
ATOM   4078  N N   . LEU A 1 567 ? 126.309 128.595 120.830 1.00 43.23  ?  556 LEU A N   1 
ATOM   4079  C CA  . LEU A 1 567 ? 126.599 127.857 119.607 1.00 43.23  ?  556 LEU A CA  1 
ATOM   4080  C C   . LEU A 1 567 ? 125.515 126.832 119.315 1.00 43.23  ?  556 LEU A C   1 
ATOM   4081  O O   . LEU A 1 567 ? 125.115 126.652 118.158 1.00 43.23  ?  556 LEU A O   1 
ATOM   4082  C CB  . LEU A 1 567 ? 127.965 127.183 119.721 1.00 43.23  ?  556 LEU A CB  1 
ATOM   4083  C CG  . LEU A 1 567 ? 128.524 126.407 118.531 1.00 43.23  ?  556 LEU A CG  1 
ATOM   4084  C CD1 . LEU A 1 567 ? 128.205 127.094 117.223 1.00 43.23  ?  556 LEU A CD1 1 
ATOM   4085  C CD2 . LEU A 1 567 ? 130.013 126.246 118.689 1.00 43.23  ?  556 LEU A CD2 1 
ATOM   4086  N N   . ILE A 1 568 ? 125.018 126.157 120.353 1.00 46.21  ?  557 ILE A N   1 
ATOM   4087  C CA  . ILE A 1 568 ? 123.951 125.180 120.165 1.00 46.21  ?  557 ILE A CA  1 
ATOM   4088  C C   . ILE A 1 568 ? 122.661 125.871 119.740 1.00 46.21  ?  557 ILE A C   1 
ATOM   4089  O O   . ILE A 1 568 ? 121.900 125.346 118.922 1.00 46.21  ?  557 ILE A O   1 
ATOM   4090  C CB  . ILE A 1 568 ? 123.772 124.351 121.449 1.00 46.21  ?  557 ILE A CB  1 
ATOM   4091  C CG1 . ILE A 1 568 ? 124.939 123.382 121.613 1.00 46.21  ?  557 ILE A CG1 1 
ATOM   4092  C CG2 . ILE A 1 568 ? 122.465 123.596 121.436 1.00 46.21  ?  557 ILE A CG2 1 
ATOM   4093  C CD1 . ILE A 1 568 ? 124.908 122.623 122.903 1.00 46.21  ?  557 ILE A CD1 1 
ATOM   4094  N N   . ASP A 1 569 ? 122.401 127.063 120.276 1.00 49.39  ?  558 ASP A N   1 
ATOM   4095  C CA  . ASP A 1 569 ? 121.243 127.833 119.834 1.00 49.39  ?  558 ASP A CA  1 
ATOM   4096  C C   . ASP A 1 569 ? 121.396 128.287 118.388 1.00 49.39  ?  558 ASP A C   1 
ATOM   4097  O O   . ASP A 1 569 ? 120.411 128.369 117.648 1.00 49.39  ?  558 ASP A O   1 
ATOM   4098  C CB  . ASP A 1 569 ? 121.038 129.044 120.741 1.00 49.39  ?  558 ASP A CB  1 
ATOM   4099  C CG  . ASP A 1 569 ? 120.603 128.664 122.134 1.00 49.39  ?  558 ASP A CG  1 
ATOM   4100  O OD1 . ASP A 1 569 ? 120.488 127.453 122.416 1.00 49.39  ?  558 ASP A OD1 1 
ATOM   4101  O OD2 . ASP A 1 569 ? 120.373 129.580 122.950 1.00 49.39  -1 558 ASP A OD2 1 
ATOM   4102  N N   . ALA A 1 570 ? 122.625 128.600 117.974 1.00 46.20  ?  559 ALA A N   1 
ATOM   4103  C CA  . ALA A 1 570 ? 122.851 129.102 116.625 1.00 46.20  ?  559 ALA A CA  1 
ATOM   4104  C C   . ALA A 1 570 ? 122.703 128.002 115.586 1.00 46.20  ?  559 ALA A C   1 
ATOM   4105  O O   . ALA A 1 570 ? 122.028 128.193 114.569 1.00 46.20  ?  559 ALA A O   1 
ATOM   4106  C CB  . ALA A 1 570 ? 124.234 129.742 116.532 1.00 46.20  ?  559 ALA A CB  1 
ATOM   4107  N N   . VAL A 1 571 ? 123.323 126.844 115.819 1.00 46.99  ?  560 VAL A N   1 
ATOM   4108  C CA  . VAL A 1 571 ? 123.253 125.781 114.819 1.00 46.99  ?  560 VAL A CA  1 
ATOM   4109  C C   . VAL A 1 571 ? 121.865 125.154 114.770 1.00 46.99  ?  560 VAL A C   1 
ATOM   4110  O O   . VAL A 1 571 ? 121.482 124.577 113.748 1.00 46.99  ?  560 VAL A O   1 
ATOM   4111  C CB  . VAL A 1 571 ? 124.339 124.729 115.077 1.00 46.99  ?  560 VAL A CB  1 
ATOM   4112  C CG1 . VAL A 1 571 ? 125.705 125.368 115.016 1.00 46.99  ?  560 VAL A CG1 1 
ATOM   4113  C CG2 . VAL A 1 571 ? 124.127 124.058 116.415 1.00 46.99  ?  560 VAL A CG2 1 
ATOM   4114  N N   . GLY A 1 572 ? 121.093 125.256 115.849 1.00 50.36  ?  561 GLY A N   1 
ATOM   4115  C CA  . GLY A 1 572 ? 119.733 124.765 115.877 1.00 50.36  ?  561 GLY A CA  1 
ATOM   4116  C C   . GLY A 1 572 ? 119.543 123.410 116.520 1.00 50.36  ?  561 GLY A C   1 
ATOM   4117  O O   . GLY A 1 572 ? 118.405 122.935 116.590 1.00 50.36  ?  561 GLY A O   1 
ATOM   4118  N N   . PHE A 1 573 ? 120.612 122.775 116.990 1.00 53.13  ?  562 PHE A N   1 
ATOM   4119  C CA  . PHE A 1 573 ? 120.521 121.446 117.574 1.00 53.13  ?  562 PHE A CA  1 
ATOM   4120  C C   . PHE A 1 573 ? 121.717 121.236 118.487 1.00 53.13  ?  562 PHE A C   1 
ATOM   4121  O O   . PHE A 1 573 ? 122.629 122.061 118.551 1.00 53.13  ?  562 PHE A O   1 
ATOM   4122  C CB  . PHE A 1 573 ? 120.461 120.364 116.492 1.00 53.13  ?  562 PHE A CB  1 
ATOM   4123  C CG  . PHE A 1 573 ? 121.528 120.491 115.446 1.00 53.13  ?  562 PHE A CG  1 
ATOM   4124  C CD1 . PHE A 1 573 ? 122.772 119.925 115.632 1.00 53.13  ?  562 PHE A CD1 1 
ATOM   4125  C CD2 . PHE A 1 573 ? 121.288 121.182 114.275 1.00 53.13  ?  562 PHE A CD2 1 
ATOM   4126  C CE1 . PHE A 1 573 ? 123.752 120.047 114.674 1.00 53.13  ?  562 PHE A CE1 1 
ATOM   4127  C CE2 . PHE A 1 573 ? 122.268 121.306 113.316 1.00 53.13  ?  562 PHE A CE2 1 
ATOM   4128  C CZ  . PHE A 1 573 ? 123.500 120.736 113.517 1.00 53.13  ?  562 PHE A CZ  1 
ATOM   4129  N N   . SER A 1 574 ? 121.695 120.113 119.202 1.00 54.39  ?  563 SER A N   1 
ATOM   4130  C CA  . SER A 1 574 ? 122.814 119.695 120.030 1.00 54.39  ?  563 SER A CA  1 
ATOM   4131  C C   . SER A 1 574 ? 123.553 118.575 119.322 1.00 54.39  ?  563 SER A C   1 
ATOM   4132  O O   . SER A 1 574 ? 122.955 117.518 119.079 1.00 54.39  ?  563 SER A O   1 
ATOM   4133  C CB  . SER A 1 574 ? 122.330 119.226 121.397 1.00 54.39  ?  563 SER A CB  1 
ATOM   4134  O OG  . SER A 1 574 ? 123.324 119.432 122.383 1.00 54.39  ?  563 SER A OG  1 
ATOM   4135  N N   . PRO A 1 575 ? 124.825 118.752 118.956 1.00 54.99  ?  564 PRO A N   1 
ATOM   4136  C CA  . PRO A 1 575 ? 125.557 117.665 118.287 1.00 54.99  ?  564 PRO A CA  1 
ATOM   4137  C C   . PRO A 1 575 ? 125.594 116.366 119.076 1.00 54.99  ?  564 PRO A C   1 
ATOM   4138  O O   . PRO A 1 575 ? 125.499 115.291 118.468 1.00 54.99  ?  564 PRO A O   1 
ATOM   4139  C CB  . PRO A 1 575 ? 126.965 118.248 118.106 1.00 54.99  ?  564 PRO A CB  1 
ATOM   4140  C CG  . PRO A 1 575 ? 127.013 119.456 118.983 1.00 54.99  ?  564 PRO A CG  1 
ATOM   4141  C CD  . PRO A 1 575 ? 125.630 119.977 119.046 1.00 54.99  ?  564 PRO A CD  1 
ATOM   4142  N N   . LEU A 1 576 ? 125.709 116.425 120.401 1.00 57.01  ?  565 LEU A N   1 
ATOM   4143  C CA  . LEU A 1 576 ? 125.730 115.219 121.216 1.00 57.01  ?  565 LEU A CA  1 
ATOM   4144  C C   . LEU A 1 576 ? 124.389 114.497 121.205 1.00 57.01  ?  565 LEU A C   1 
ATOM   4145  O O   . LEU A 1 576 ? 124.350 113.266 121.197 1.00 57.01  ?  565 LEU A O   1 
ATOM   4146  C CB  . LEU A 1 576 ? 126.131 115.566 122.649 1.00 57.01  ?  565 LEU A CB  1 
ATOM   4147  C CG  . LEU A 1 576 ? 126.510 114.407 123.563 1.00 57.01  ?  565 LEU A CG  1 
ATOM   4148  C CD1 . LEU A 1 576 ? 127.422 113.437 122.846 1.00 57.01  ?  565 LEU A CD1 1 
ATOM   4149  C CD2 . LEU A 1 576 ? 127.174 114.942 124.809 1.00 57.01  ?  565 LEU A CD2 1 
ATOM   4150  N N   . ARG A 1 577 ? 123.294 115.218 121.340 1.00 58.12  ?  566 ARG A N   1 
ATOM   4151  C CA  . ARG A 1 577 ? 122.020 114.555 121.316 1.00 58.12  ?  566 ARG A CA  1 
ATOM   4152  C C   . ARG A 1 577 ? 121.893 113.767 120.019 1.00 58.12  ?  566 ARG A C   1 
ATOM   4153  O O   . ARG A 1 577 ? 121.400 112.645 120.019 1.00 58.12  ?  566 ARG A O   1 
ATOM   4154  C CB  . ARG A 1 577 ? 120.890 115.567 121.467 1.00 58.12  ?  566 ARG A CB  1 
ATOM   4155  C CG  . ARG A 1 577 ? 119.541 114.968 121.804 1.00 58.12  ?  566 ARG A CG  1 
ATOM   4156  C CD  . ARG A 1 577 ? 118.671 116.047 122.412 1.00 58.12  ?  566 ARG A CD  1 
ATOM   4157  N NE  . ARG A 1 577 ? 119.361 116.684 123.528 1.00 58.12  ?  566 ARG A NE  1 
ATOM   4158  C CZ  . ARG A 1 577 ? 119.037 117.868 124.033 1.00 58.12  ?  566 ARG A CZ  1 
ATOM   4159  N NH1 . ARG A 1 577 ? 118.036 118.562 123.513 1.00 58.12  1  566 ARG A NH1 1 
ATOM   4160  N NH2 . ARG A 1 577 ? 119.724 118.364 125.052 1.00 58.12  ?  566 ARG A NH2 1 
ATOM   4161  N N   . ILE A 1 578 ? 122.367 114.335 118.920 1.00 59.51  ?  567 ILE A N   1 
ATOM   4162  C CA  . ILE A 1 578 ? 122.285 113.666 117.627 1.00 59.51  ?  567 ILE A CA  1 
ATOM   4163  C C   . ILE A 1 578 ? 123.104 112.379 117.587 1.00 59.51  ?  567 ILE A C   1 
ATOM   4164  O O   . ILE A 1 578 ? 122.621 111.361 117.109 1.00 59.51  ?  567 ILE A O   1 
ATOM   4165  C CB  . ILE A 1 578 ? 122.730 114.601 116.478 1.00 59.51  ?  567 ILE A CB  1 
ATOM   4166  C CG1 . ILE A 1 578 ? 121.890 115.878 116.466 1.00 59.51  ?  567 ILE A CG1 1 
ATOM   4167  C CG2 . ILE A 1 578 ? 122.639 113.887 115.140 1.00 59.51  ?  567 ILE A CG2 1 
ATOM   4168  C CD1 . ILE A 1 578 ? 120.422 115.640 116.206 1.00 59.51  ?  567 ILE A CD1 1 
ATOM   4169  N N   . LEU A 1 579 ? 124.330 112.415 118.089 1.00 61.20  ?  568 LEU A N   1 
ATOM   4170  C CA  . LEU A 1 579 ? 125.184 111.234 118.109 1.00 61.20  ?  568 LEU A CA  1 
ATOM   4171  C C   . LEU A 1 579 ? 124.556 110.104 118.890 1.00 61.20  ?  568 LEU A C   1 
ATOM   4172  O O   . LEU A 1 579 ? 124.594 108.957 118.466 1.00 61.20  ?  568 LEU A O   1 
ATOM   4173  C CB  . LEU A 1 579 ? 126.539 111.564 118.729 1.00 61.20  ?  568 LEU A CB  1 
ATOM   4174  C CG  . LEU A 1 579 ? 127.572 110.438 118.765 1.00 61.20  ?  568 LEU A CG  1 
ATOM   4175  C CD1 . LEU A 1 579 ? 127.863 109.931 117.361 1.00 61.20  ?  568 LEU A CD1 1 
ATOM   4176  C CD2 . LEU A 1 579 ? 128.849 110.903 119.444 1.00 61.20  ?  568 LEU A CD2 1 
ATOM   4177  N N   . ARG A 1 580 ? 123.963 110.427 120.030 1.00 59.66  ?  569 ARG A N   1 
ATOM   4178  C CA  . ARG A 1 580 ? 123.348 109.411 120.869 1.00 59.66  ?  569 ARG A CA  1 
ATOM   4179  C C   . ARG A 1 580 ? 122.152 108.785 120.184 1.00 59.66  ?  569 ARG A C   1 
ATOM   4180  O O   . ARG A 1 580 ? 121.969 107.579 120.238 1.00 59.66  ?  569 ARG A O   1 
ATOM   4181  C CB  . ARG A 1 580 ? 122.959 110.020 122.217 1.00 59.66  ?  569 ARG A CB  1 
ATOM   4182  C CG  . ARG A 1 580 ? 124.155 110.461 123.039 1.00 59.66  ?  569 ARG A CG  1 
ATOM   4183  C CD  . ARG A 1 580 ? 123.743 111.177 124.310 1.00 59.66  ?  569 ARG A CD  1 
ATOM   4184  N NE  . ARG A 1 580 ? 124.894 111.455 125.161 1.00 59.66  ?  569 ARG A NE  1 
ATOM   4185  C CZ  . ARG A 1 580 ? 124.825 112.060 126.340 1.00 59.66  ?  569 ARG A CZ  1 
ATOM   4186  N NH1 . ARG A 1 580 ? 123.655 112.459 126.814 1.00 59.66  1  569 ARG A NH1 1 
ATOM   4187  N NH2 . ARG A 1 580 ? 125.927 112.268 127.046 1.00 59.66  ?  569 ARG A NH2 1 
ATOM   4188  N N   . LYS A 1 581 ? 121.342 109.600 119.530 1.00 65.66  ?  570 LYS A N   1 
ATOM   4189  C CA  . LYS A 1 581 ? 120.178 109.088 118.812 1.00 65.66  ?  570 LYS A CA  1 
ATOM   4190  C C   . LYS A 1 581 ? 120.580 108.261 117.601 1.00 65.66  ?  570 LYS A C   1 
ATOM   4191  O O   . LYS A 1 581 ? 119.921 107.282 117.283 1.00 65.66  ?  570 LYS A O   1 
ATOM   4192  C CB  . LYS A 1 581 ? 119.249 110.233 118.405 1.00 65.66  ?  570 LYS A CB  1 
ATOM   4193  C CG  . LYS A 1 581 ? 118.603 110.945 119.577 1.00 65.66  ?  570 LYS A CG  1 
ATOM   4194  C CD  . LYS A 1 581 ? 117.876 112.192 119.113 1.00 65.66  ?  570 LYS A CD  1 
ATOM   4195  C CE  . LYS A 1 581 ? 117.150 112.869 120.263 1.00 65.66  ?  570 LYS A CE  1 
ATOM   4196  N NZ  . LYS A 1 581 ? 116.494 114.134 119.834 1.00 65.66  1  570 LYS A NZ  1 
ATOM   4197  N N   . ARG A 1 582 ? 121.649 108.644 116.923 1.00 68.53  ?  571 ARG A N   1 
ATOM   4198  C CA  . ARG A 1 582 ? 122.138 107.864 115.793 1.00 68.53  ?  571 ARG A CA  1 
ATOM   4199  C C   . ARG A 1 582 ? 122.746 106.564 116.270 1.00 68.53  ?  571 ARG A C   1 
ATOM   4200  O O   . ARG A 1 582 ? 122.598 105.536 115.626 1.00 68.53  ?  571 ARG A O   1 
ATOM   4201  C CB  . ARG A 1 582 ? 123.174 108.648 114.995 1.00 68.53  ?  571 ARG A CB  1 
ATOM   4202  C CG  . ARG A 1 582 ? 122.638 109.833 114.221 1.00 68.53  ?  571 ARG A CG  1 
ATOM   4203  C CD  . ARG A 1 582 ? 123.771 110.511 113.476 1.00 68.53  ?  571 ARG A CD  1 
ATOM   4204  N NE  . ARG A 1 582 ? 123.319 111.660 112.703 1.00 68.53  ?  571 ARG A NE  1 
ATOM   4205  C CZ  . ARG A 1 582 ? 124.118 112.418 111.962 1.00 68.53  ?  571 ARG A CZ  1 
ATOM   4206  N NH1 . ARG A 1 582 ? 125.412 112.145 111.892 1.00 68.53  1  571 ARG A NH1 1 
ATOM   4207  N NH2 . ARG A 1 582 ? 123.625 113.445 111.291 1.00 68.53  ?  571 ARG A NH2 1 
ATOM   4208  N N   . ASN A 1 583 ? 123.442 106.607 117.396 1.00 67.76  ?  572 ASN A N   1 
ATOM   4209  C CA  . ASN A 1 583 ? 124.025 105.403 117.961 1.00 67.76  ?  572 ASN A CA  1 
ATOM   4210  C C   . ASN A 1 583 ? 122.919 104.478 118.423 1.00 67.76  ?  572 ASN A C   1 
ATOM   4211  O O   . ASN A 1 583 ? 123.051 103.268 118.323 1.00 67.76  ?  572 ASN A O   1 
ATOM   4212  C CB  . ASN A 1 583 ? 124.972 105.743 119.105 1.00 67.76  ?  572 ASN A CB  1 
ATOM   4213  C CG  . ASN A 1 583 ? 126.414 105.847 118.658 1.00 67.76  ?  572 ASN A CG  1 
ATOM   4214  O OD1 . ASN A 1 583 ? 126.855 105.110 117.780 1.00 67.76  ?  572 ASN A OD1 1 
ATOM   4215  N ND2 . ASN A 1 583 ? 127.160 106.755 119.271 1.00 67.76  ?  572 ASN A ND2 1 
ATOM   4216  N N   . LYS A 1 584 ? 121.822 105.041 118.906 1.00 70.81  ?  573 LYS A N   1 
ATOM   4217  C CA  . LYS A 1 584 ? 120.690 104.227 119.307 1.00 70.81  ?  573 LYS A CA  1 
ATOM   4218  C C   . LYS A 1 584 ? 120.047 103.611 118.084 1.00 70.81  ?  573 LYS A C   1 
ATOM   4219  O O   . LYS A 1 584 ? 119.729 102.429 118.081 1.00 70.81  ?  573 LYS A O   1 
ATOM   4220  C CB  . LYS A 1 584 ? 119.681 105.073 120.074 1.00 70.81  ?  573 LYS A CB  1 
ATOM   4221  C CG  . LYS A 1 584 ? 118.432 104.334 120.508 1.00 70.81  ?  573 LYS A CG  1 
ATOM   4222  C CD  . LYS A 1 584 ? 117.515 105.254 121.294 1.00 70.81  ?  573 LYS A CD  1 
ATOM   4223  C CE  . LYS A 1 584 ? 116.229 104.547 121.691 1.00 70.81  ?  573 LYS A CE  1 
ATOM   4224  N NZ  . LYS A 1 584 ? 115.328 105.440 122.471 1.00 70.81  1  573 LYS A NZ  1 
ATOM   4225  N N   . ALA A 1 585 ? 119.854 104.404 117.042 1.00 77.34  ?  574 ALA A N   1 
ATOM   4226  C CA  . ALA A 1 585 ? 119.287 103.900 115.806 1.00 77.34  ?  574 ALA A CA  1 
ATOM   4227  C C   . ALA A 1 585 ? 120.168 102.810 115.246 1.00 77.34  ?  574 ALA A C   1 
ATOM   4228  O O   . ALA A 1 585 ? 119.699 101.722 114.941 1.00 77.34  ?  574 ALA A O   1 
ATOM   4229  C CB  . ALA A 1 585 ? 119.148 105.022 114.804 1.00 77.34  ?  574 ALA A CB  1 
ATOM   4230  N N   . LEU A 1 586 ? 121.454 103.102 115.116 1.00 83.10  ?  575 LEU A N   1 
ATOM   4231  C CA  . LEU A 1 586 ? 122.384 102.112 114.587 1.00 83.10  ?  575 LEU A CA  1 
ATOM   4232  C C   . LEU A 1 586 ? 122.343 100.828 115.404 1.00 83.10  ?  575 LEU A C   1 
ATOM   4233  O O   . LEU A 1 586 ? 122.454 99.729  114.849 1.00 83.10  ?  575 LEU A O   1 
ATOM   4234  C CB  . LEU A 1 586 ? 123.797 102.688 114.555 1.00 83.10  ?  575 LEU A CB  1 
ATOM   4235  C CG  . LEU A 1 586 ? 124.869 101.857 113.855 1.00 83.10  ?  575 LEU A CG  1 
ATOM   4236  C CD1 . LEU A 1 586 ? 124.528 101.650 112.390 1.00 83.10  ?  575 LEU A CD1 1 
ATOM   4237  C CD2 . LEU A 1 586 ? 126.222 102.523 114.003 1.00 83.10  ?  575 LEU A CD2 1 
ATOM   4238  N N   . ARG A 1 587 ? 122.183 100.945 116.724 1.00 84.06  ?  576 ARG A N   1 
ATOM   4239  C CA  . ARG A 1 587 ? 122.005 99.760  117.554 1.00 84.06  ?  576 ARG A CA  1 
ATOM   4240  C C   . ARG A 1 587 ? 120.755 98.993  117.147 1.00 84.06  ?  576 ARG A C   1 
ATOM   4241  O O   . ARG A 1 587 ? 120.787 97.764  117.014 1.00 84.06  ?  576 ARG A O   1 
ATOM   4242  C CB  . ARG A 1 587 ? 121.929 100.156 119.026 1.00 84.06  ?  576 ARG A CB  1 
ATOM   4243  C CG  . ARG A 1 587 ? 123.252 100.564 119.629 1.00 84.06  ?  576 ARG A CG  1 
ATOM   4244  C CD  . ARG A 1 587 ? 123.102 100.881 121.103 1.00 84.06  ?  576 ARG A CD  1 
ATOM   4245  N NE  . ARG A 1 587 ? 124.212 100.352 121.886 1.00 84.06  ?  576 ARG A NE  1 
ATOM   4246  C CZ  . ARG A 1 587 ? 124.230 99.145  122.435 1.00 84.06  ?  576 ARG A CZ  1 
ATOM   4247  N NH1 . ARG A 1 587 ? 123.195 98.332  122.287 1.00 84.06  1  576 ARG A NH1 1 
ATOM   4248  N NH2 . ARG A 1 587 ? 125.286 98.749  123.129 1.00 84.06  ?  576 ARG A NH2 1 
ATOM   4249  N N   . LYS A 1 588 ? 119.645 99.704  116.941 1.00 90.75  ?  577 LYS A N   1 
ATOM   4250  C CA  . LYS A 1 588 ? 118.422 99.033  116.509 1.00 90.75  ?  577 LYS A CA  1 
ATOM   4251  C C   . LYS A 1 588 ? 118.576 98.414  115.126 1.00 90.75  ?  577 LYS A C   1 
ATOM   4252  O O   . LYS A 1 588 ? 118.052 97.323  114.874 1.00 90.75  ?  577 LYS A O   1 
ATOM   4253  C CB  . LYS A 1 588 ? 117.250 100.011 116.528 1.00 90.75  ?  577 LYS A CB  1 
ATOM   4254  C CG  . LYS A 1 588 ? 115.918 99.372  116.197 1.00 90.75  ?  577 LYS A CG  1 
ATOM   4255  C CD  . LYS A 1 588 ? 114.793 100.386 116.232 1.00 90.75  ?  577 LYS A CD  1 
ATOM   4256  C CE  . LYS A 1 588 ? 114.607 100.953 117.625 1.00 90.75  ?  577 LYS A CE  1 
ATOM   4257  N NZ  . LYS A 1 588 ? 113.320 101.689 117.746 1.00 90.75  1  577 LYS A NZ  1 
ATOM   4258  N N   . ILE A 1 589 ? 119.299 99.084  114.227 1.00 94.76  ?  578 ILE A N   1 
ATOM   4259  C CA  . ILE A 1 589 ? 119.541 98.541  112.893 1.00 94.76  ?  578 ILE A CA  1 
ATOM   4260  C C   . ILE A 1 589 ? 120.333 97.244  112.982 1.00 94.76  ?  578 ILE A C   1 
ATOM   4261  O O   . ILE A 1 589 ? 119.985 96.241  112.349 1.00 94.76  ?  578 ILE A O   1 
ATOM   4262  C CB  . ILE A 1 589 ? 120.265 99.577  112.015 1.00 94.76  ?  578 ILE A CB  1 
ATOM   4263  C CG1 . ILE A 1 589 ? 119.275 100.607 111.471 1.00 94.76  ?  578 ILE A CG1 1 
ATOM   4264  C CG2 . ILE A 1 589 ? 120.999 98.895  110.875 1.00 94.76  ?  578 ILE A CG2 1 
ATOM   4265  C CD1 . ILE A 1 589 ? 119.939 101.761 110.757 1.00 94.76  ?  578 ILE A CD1 1 
ATOM   4266  N N   . ARG A 1 590 ? 121.416 97.246  113.760 1.00 95.47  ?  579 ARG A N   1 
ATOM   4267  C CA  . ARG A 1 590 ? 122.218 96.038  113.909 1.00 95.47  ?  579 ARG A CA  1 
ATOM   4268  C C   . ARG A 1 590 ? 121.424 94.916  114.560 1.00 95.47  ?  579 ARG A C   1 
ATOM   4269  O O   . ARG A 1 590 ? 121.548 93.753  114.154 1.00 95.47  ?  579 ARG A O   1 
ATOM   4270  C CB  . ARG A 1 590 ? 123.478 96.340  114.714 1.00 95.47  ?  579 ARG A CB  1 
ATOM   4271  C CG  . ARG A 1 590 ? 124.496 97.161  113.951 1.00 95.47  ?  579 ARG A CG  1 
ATOM   4272  C CD  . ARG A 1 590 ? 125.530 97.770  114.870 1.00 95.47  ?  579 ARG A CD  1 
ATOM   4273  N NE  . ARG A 1 590 ? 126.624 98.373  114.119 1.00 95.47  ?  579 ARG A NE  1 
ATOM   4274  C CZ  . ARG A 1 590 ? 127.464 99.271  114.618 1.00 95.47  ?  579 ARG A CZ  1 
ATOM   4275  N NH1 . ARG A 1 590 ? 127.336 99.675  115.876 1.00 95.47  1  579 ARG A NH1 1 
ATOM   4276  N NH2 . ARG A 1 590 ? 128.434 99.768  113.862 1.00 95.47  ?  579 ARG A NH2 1 
ATOM   4277  N N   . LYS A 1 591 ? 120.599 95.241  115.558 1.00 100.75 ?  580 LYS A N   1 
ATOM   4278  C CA  . LYS A 1 591 ? 119.759 94.230  116.190 1.00 100.75 ?  580 LYS A CA  1 
ATOM   4279  C C   . LYS A 1 591 ? 118.795 93.611  115.187 1.00 100.75 ?  580 LYS A C   1 
ATOM   4280  O O   . LYS A 1 591 ? 118.646 92.385  115.130 1.00 100.75 ?  580 LYS A O   1 
ATOM   4281  C CB  . LYS A 1 591 ? 118.994 94.843  117.362 1.00 100.75 ?  580 LYS A CB  1 
ATOM   4282  C CG  . LYS A 1 591 ? 117.945 93.926  117.964 1.00 100.75 ?  580 LYS A CG  1 
ATOM   4283  C CD  . LYS A 1 591 ? 117.193 94.610  119.094 1.00 100.75 ?  580 LYS A CD  1 
ATOM   4284  C CE  . LYS A 1 591 ? 115.926 95.280  118.594 1.00 100.75 ?  580 LYS A CE  1 
ATOM   4285  N NZ  . LYS A 1 591 ? 115.587 96.489  119.392 1.00 100.75 1  580 LYS A NZ  1 
ATOM   4286  N N   . LEU A 1 592 ? 118.131 94.444  114.383 1.00 105.77 ?  581 LEU A N   1 
ATOM   4287  C CA  . LEU A 1 592 ? 117.174 93.925  113.413 1.00 105.77 ?  581 LEU A CA  1 
ATOM   4288  C C   . LEU A 1 592 ? 117.848 93.223  112.243 1.00 105.77 ?  581 LEU A C   1 
ATOM   4289  O O   . LEU A 1 592 ? 117.202 92.418  111.565 1.00 105.77 ?  581 LEU A O   1 
ATOM   4290  C CB  . LEU A 1 592 ? 116.281 95.051  112.895 1.00 105.77 ?  581 LEU A CB  1 
ATOM   4291  C CG  . LEU A 1 592 ? 115.289 95.630  113.902 1.00 105.77 ?  581 LEU A CG  1 
ATOM   4292  C CD1 . LEU A 1 592 ? 114.422 96.698  113.256 1.00 105.77 ?  581 LEU A CD1 1 
ATOM   4293  C CD2 . LEU A 1 592 ? 114.432 94.531  114.499 1.00 105.77 ?  581 LEU A CD2 1 
ATOM   4294  N N   . GLN A 1 593 ? 119.126 93.507  111.981 1.00 106.49 ?  582 GLN A N   1 
ATOM   4295  C CA  . GLN A 1 593 ? 119.768 92.895  110.823 1.00 106.49 ?  582 GLN A CA  1 
ATOM   4296  C C   . GLN A 1 593 ? 120.461 91.586  111.179 1.00 106.49 ?  582 GLN A C   1 
ATOM   4297  O O   . GLN A 1 593 ? 120.514 90.673  110.349 1.00 106.49 ?  582 GLN A O   1 
ATOM   4298  C CB  . GLN A 1 593 ? 120.754 93.871  110.177 1.00 106.49 ?  582 GLN A CB  1 
ATOM   4299  C CG  . GLN A 1 593 ? 122.072 94.026  110.904 1.00 106.49 ?  582 GLN A CG  1 
ATOM   4300  C CD  . GLN A 1 593 ? 123.247 94.097  109.954 1.00 106.49 ?  582 GLN A CD  1 
ATOM   4301  O OE1 . GLN A 1 593 ? 123.131 93.754  108.778 1.00 106.49 ?  582 GLN A OE1 1 
ATOM   4302  N NE2 . GLN A 1 593 ? 124.390 94.545  110.458 1.00 106.49 ?  582 GLN A NE2 1 
ATOM   4303  N N   . LYS A 1 594 ? 121.001 91.466  112.394 1.00 106.93 ?  583 LYS A N   1 
ATOM   4304  C CA  . LYS A 1 594 ? 121.604 90.191  112.769 1.00 106.93 ?  583 LYS A CA  1 
ATOM   4305  C C   . LYS A 1 594 ? 120.540 89.177  113.171 1.00 106.93 ?  583 LYS A C   1 
ATOM   4306  O O   . LYS A 1 594 ? 120.826 87.979  113.257 1.00 106.93 ?  583 LYS A O   1 
ATOM   4307  C CB  . LYS A 1 594 ? 122.638 90.389  113.882 1.00 106.93 ?  583 LYS A CB  1 
ATOM   4308  N N   . GLN A 1 595 ? 119.313 89.640  113.425 1.00 109.28 ?  584 GLN A N   1 
ATOM   4309  C CA  . GLN A 1 595 ? 118.198 88.729  113.645 1.00 109.28 ?  584 GLN A CA  1 
ATOM   4310  C C   . GLN A 1 595 ? 117.651 88.168  112.340 1.00 109.28 ?  584 GLN A C   1 
ATOM   4311  O O   . GLN A 1 595 ? 116.794 87.279  112.371 1.00 109.28 ?  584 GLN A O   1 
ATOM   4312  C CB  . GLN A 1 595 ? 117.075 89.434  114.405 1.00 109.28 ?  584 GLN A CB  1 
ATOM   4313  C CG  . GLN A 1 595 ? 117.211 89.394  115.914 1.00 109.28 ?  584 GLN A CG  1 
ATOM   4314  C CD  . GLN A 1 595 ? 116.166 90.243  116.610 1.00 109.28 ?  584 GLN A CD  1 
ATOM   4315  O OE1 . GLN A 1 595 ? 116.403 90.777  117.694 1.00 109.28 ?  584 GLN A OE1 1 
ATOM   4316  N NE2 . GLN A 1 595 ? 115.001 90.374  115.987 1.00 109.28 ?  584 GLN A NE2 1 
ATOM   4317  N N   . GLY A 1 596 ? 118.117 88.674  111.198 1.00 113.92 ?  585 GLY A N   1 
ATOM   4318  C CA  . GLY A 1 596 ? 117.606 88.268  109.909 1.00 113.92 ?  585 GLY A CA  1 
ATOM   4319  C C   . GLY A 1 596 ? 116.356 88.992  109.462 1.00 113.92 ?  585 GLY A C   1 
ATOM   4320  O O   . GLY A 1 596 ? 115.839 88.692  108.378 1.00 113.92 ?  585 GLY A O   1 
ATOM   4321  N N   . LEU A 1 597 ? 115.851 89.936  110.261 1.00 116.59 ?  586 LEU A N   1 
ATOM   4322  C CA  . LEU A 1 597 ? 114.602 90.608  109.924 1.00 116.59 ?  586 LEU A CA  1 
ATOM   4323  C C   . LEU A 1 597 ? 114.776 91.536  108.728 1.00 116.59 ?  586 LEU A C   1 
ATOM   4324  O O   . LEU A 1 597 ? 113.828 91.761  107.964 1.00 116.59 ?  586 LEU A O   1 
ATOM   4325  C CB  . LEU A 1 597 ? 114.086 91.376  111.139 1.00 116.59 ?  586 LEU A CB  1 
ATOM   4326  C CG  . LEU A 1 597 ? 113.204 90.552  112.078 1.00 116.59 ?  586 LEU A CG  1 
ATOM   4327  C CD1 . LEU A 1 597 ? 112.929 91.305  113.365 1.00 116.59 ?  586 LEU A CD1 1 
ATOM   4328  C CD2 . LEU A 1 597 ? 111.902 90.173  111.388 1.00 116.59 ?  586 LEU A CD2 1 
ATOM   4329  N N   . LEU A 1 598 ? 115.971 92.087  108.548 1.00 115.87 ?  587 LEU A N   1 
ATOM   4330  C CA  . LEU A 1 598 ? 116.302 92.910  107.393 1.00 115.87 ?  587 LEU A CA  1 
ATOM   4331  C C   . LEU A 1 598 ? 117.647 92.465  106.834 1.00 115.87 ?  587 LEU A C   1 
ATOM   4332  O O   . LEU A 1 598 ? 118.440 91.838  107.542 1.00 115.87 ?  587 LEU A O   1 
ATOM   4333  C CB  . LEU A 1 598 ? 116.323 94.398  107.761 1.00 115.87 ?  587 LEU A CB  1 
ATOM   4334  C CG  . LEU A 1 598 ? 117.480 95.000  108.563 1.00 115.87 ?  587 LEU A CG  1 
ATOM   4335  C CD1 . LEU A 1 598 ? 118.602 95.483  107.660 1.00 115.87 ?  587 LEU A CD1 1 
ATOM   4336  C CD2 . LEU A 1 598 ? 116.973 96.144  109.425 1.00 115.87 ?  587 LEU A CD2 1 
ATOM   4337  N N   . GLN A 1 599 ? 117.895 92.785  105.569 1.00 122.49 ?  588 GLN A N   1 
ATOM   4338  C CA  . GLN A 1 599 ? 119.090 92.347  104.864 1.00 122.49 ?  588 GLN A CA  1 
ATOM   4339  C C   . GLN A 1 599 ? 119.929 93.547  104.447 1.00 122.49 ?  588 GLN A C   1 
ATOM   4340  O O   . GLN A 1 599 ? 119.391 94.624  104.172 1.00 122.49 ?  588 GLN A O   1 
ATOM   4341  C CB  . GLN A 1 599 ? 118.722 91.519  103.631 1.00 122.49 ?  588 GLN A CB  1 
ATOM   4342  N N   . VAL A 1 600 ? 121.243 93.351  104.393 1.00 123.88 ?  589 VAL A N   1 
ATOM   4343  C CA  . VAL A 1 600 ? 122.176 94.384  103.956 1.00 123.88 ?  589 VAL A CA  1 
ATOM   4344  C C   . VAL A 1 600 ? 122.543 94.109  102.502 1.00 123.88 ?  589 VAL A C   1 
ATOM   4345  O O   . VAL A 1 600 ? 122.774 92.957  102.117 1.00 123.88 ?  589 VAL A O   1 
ATOM   4346  C CB  . VAL A 1 600 ? 123.423 94.420  104.854 1.00 123.88 ?  589 VAL A CB  1 
ATOM   4347  N N   . THR A 1 601 ? 122.586 95.167  101.690 1.00 124.96 ?  590 THR A N   1 
ATOM   4348  C CA  . THR A 1 601 ? 122.877 95.083  100.274 1.00 124.96 ?  590 THR A CA  1 
ATOM   4349  C C   . THR A 1 601 ? 123.660 96.338  99.919  1.00 124.96 ?  590 THR A C   1 
ATOM   4350  O O   . THR A 1 601 ? 123.507 97.367  100.595 1.00 124.96 ?  590 THR A O   1 
ATOM   4351  C CB  . THR A 1 601 ? 121.577 95.006  99.451  1.00 124.96 ?  590 THR A CB  1 
ATOM   4352  O OG1 . THR A 1 601 ? 120.757 93.949  99.957  1.00 124.96 ?  590 THR A OG1 1 
ATOM   4353  C CG2 . THR A 1 601 ? 121.858 94.746  97.978  1.00 124.96 ?  590 THR A CG2 1 
ATOM   4354  N N   . PRO A 1 602 ? 124.533 96.287  98.910  1.00 125.63 ?  591 PRO A N   1 
ATOM   4355  C CA  . PRO A 1 602 ? 125.088 97.540  98.373  1.00 125.63 ?  591 PRO A CA  1 
ATOM   4356  C C   . PRO A 1 602 ? 124.023 98.553  97.985  1.00 125.63 ?  591 PRO A C   1 
ATOM   4357  O O   . PRO A 1 602 ? 124.315 99.755  97.913  1.00 125.63 ?  591 PRO A O   1 
ATOM   4358  C CB  . PRO A 1 602 ? 125.895 97.062  97.161  1.00 125.63 ?  591 PRO A CB  1 
ATOM   4359  C CG  . PRO A 1 602 ? 126.356 95.704  97.557  1.00 125.63 ?  591 PRO A CG  1 
ATOM   4360  C CD  . PRO A 1 602 ? 125.270 95.108  98.421  1.00 125.63 ?  591 PRO A CD  1 
ATOM   4361  N N   . LYS A 1 603 ? 122.791 98.104  97.732  1.00 124.23 ?  592 LYS A N   1 
ATOM   4362  C CA  . LYS A 1 603 ? 121.692 99.036  97.506  1.00 124.23 ?  592 LYS A CA  1 
ATOM   4363  C C   . LYS A 1 603 ? 121.277 99.726  98.800  1.00 124.23 ?  592 LYS A C   1 
ATOM   4364  O O   . LYS A 1 603 ? 120.995 100.930 98.808  1.00 124.23 ?  592 LYS A O   1 
ATOM   4365  C CB  . LYS A 1 603 ? 120.504 98.299  96.887  1.00 124.23 ?  592 LYS A CB  1 
ATOM   4366  N N   . GLY A 1 604 ? 121.226 98.981  99.898  1.00 122.24 ?  593 GLY A N   1 
ATOM   4367  C CA  . GLY A 1 604 ? 120.874 99.555  101.184 1.00 122.24 ?  593 GLY A CA  1 
ATOM   4368  C C   . GLY A 1 604 ? 120.282 98.495  102.096 1.00 122.24 ?  593 GLY A C   1 
ATOM   4369  O O   . GLY A 1 604 ? 120.686 97.335  102.072 1.00 122.24 ?  593 GLY A O   1 
ATOM   4370  N N   . PHE A 1 605 ? 119.330 98.935  102.915 1.00 119.41 ?  594 PHE A N   1 
ATOM   4371  C CA  . PHE A 1 605 ? 118.602 98.014  103.776 1.00 119.41 ?  594 PHE A CA  1 
ATOM   4372  C C   . PHE A 1 605 ? 117.371 97.487  103.052 1.00 119.41 ?  594 PHE A C   1 
ATOM   4373  O O   . PHE A 1 605 ? 116.557 98.265  102.543 1.00 119.41 ?  594 PHE A O   1 
ATOM   4374  C CB  . PHE A 1 605 ? 118.197 98.705  105.075 1.00 119.41 ?  594 PHE A CB  1 
ATOM   4375  C CG  . PHE A 1 605 ? 119.358 99.167  105.909 1.00 119.41 ?  594 PHE A CG  1 
ATOM   4376  C CD1 . PHE A 1 605 ? 120.274 98.257  106.408 1.00 119.41 ?  594 PHE A CD1 1 
ATOM   4377  C CD2 . PHE A 1 605 ? 119.527 100.509 106.200 1.00 119.41 ?  594 PHE A CD2 1 
ATOM   4378  C CE1 . PHE A 1 605 ? 121.338 98.677  107.181 1.00 119.41 ?  594 PHE A CE1 1 
ATOM   4379  C CE2 . PHE A 1 605 ? 120.590 100.937 106.968 1.00 119.41 ?  594 PHE A CE2 1 
ATOM   4380  C CZ  . PHE A 1 605 ? 121.497 100.020 107.460 1.00 119.41 ?  594 PHE A CZ  1 
ATOM   4381  N N   . ILE A 1 606 ? 117.229 96.164  103.009 1.00 122.04 ?  595 ILE A N   1 
ATOM   4382  C CA  . ILE A 1 606 ? 116.075 95.523  102.398 1.00 122.04 ?  595 ILE A CA  1 
ATOM   4383  C C   . ILE A 1 606 ? 115.214 94.941  103.508 1.00 122.04 ?  595 ILE A C   1 
ATOM   4384  O O   . ILE A 1 606 ? 115.680 94.149  104.332 1.00 122.04 ?  595 ILE A O   1 
ATOM   4385  C CB  . ILE A 1 606 ? 116.481 94.425  101.393 1.00 122.04 ?  595 ILE A CB  1 
ATOM   4386  C CG1 . ILE A 1 606 ? 117.471 94.987  100.367 1.00 122.04 ?  595 ILE A CG1 1 
ATOM   4387  C CG2 . ILE A 1 606 ? 115.252 93.846  100.708 1.00 122.04 ?  595 ILE A CG2 1 
ATOM   4388  C CD1 . ILE A 1 606 ? 117.661 94.108  99.147  1.00 122.04 ?  595 ILE A CD1 1 
ATOM   4389  N N   . CYS A 1 607 ? 113.947 95.337  103.524 1.00 124.21 ?  596 CYS A N   1 
ATOM   4390  C CA  . CYS A 1 607 ? 113.027 94.970  104.593 1.00 124.21 ?  596 CYS A CA  1 
ATOM   4391  C C   . CYS A 1 607 ? 111.988 94.006  104.042 1.00 124.21 ?  596 CYS A C   1 
ATOM   4392  O O   . CYS A 1 607 ? 110.977 94.432  103.473 1.00 124.21 ?  596 CYS A O   1 
ATOM   4393  C CB  . CYS A 1 607 ? 112.365 96.211  105.188 1.00 124.21 ?  596 CYS A CB  1 
ATOM   4394  S SG  . CYS A 1 607 ? 113.532 97.491  105.686 1.00 124.21 ?  596 CYS A SG  1 
ATOM   4395  N N   . THR A 1 608 ? 112.240 92.705  104.207 1.00 126.46 ?  597 THR A N   1 
ATOM   4396  C CA  . THR A 1 608 ? 111.216 91.716  103.897 1.00 126.46 ?  597 THR A CA  1 
ATOM   4397  C C   . THR A 1 608 ? 110.062 91.810  104.886 1.00 126.46 ?  597 THR A C   1 
ATOM   4398  O O   . THR A 1 608 ? 108.905 91.553  104.534 1.00 126.46 ?  597 THR A O   1 
ATOM   4399  C CB  . THR A 1 608 ? 111.821 90.311  103.900 1.00 126.46 ?  597 THR A CB  1 
ATOM   4400  O OG1 . THR A 1 608 ? 110.772 89.334  103.916 1.00 126.46 ?  597 THR A OG1 1 
ATOM   4401  C CG2 . THR A 1 608 ? 112.714 90.116  105.114 1.00 126.46 ?  597 THR A CG2 1 
ATOM   4402  N N   . VAL A 1 609 ? 110.356 92.186  106.128 1.00 126.10 ?  598 VAL A N   1 
ATOM   4403  C CA  . VAL A 1 609 ? 109.346 92.395  107.155 1.00 126.10 ?  598 VAL A CA  1 
ATOM   4404  C C   . VAL A 1 609 ? 109.298 93.877  107.486 1.00 126.10 ?  598 VAL A C   1 
ATOM   4405  O O   . VAL A 1 609 ? 110.323 94.505  107.763 1.00 126.10 ?  598 VAL A O   1 
ATOM   4406  C CB  . VAL A 1 609 ? 109.634 91.565  108.426 1.00 126.10 ?  598 VAL A CB  1 
ATOM   4407  C CG1 . VAL A 1 609 ? 108.630 91.897  109.519 1.00 126.10 ?  598 VAL A CG1 1 
ATOM   4408  C CG2 . VAL A 1 609 ? 109.616 90.079  108.103 1.00 126.10 ?  598 VAL A CG2 1 
ATOM   4409  N N   . ASP A 1 610 ? 108.095 94.437  107.450 1.00 127.07 ?  599 ASP A N   1 
ATOM   4410  C CA  . ASP A 1 610 ? 107.878 95.835  107.768 1.00 127.07 ?  599 ASP A CA  1 
ATOM   4411  C C   . ASP A 1 610 ? 107.052 95.944  109.053 1.00 127.07 ?  599 ASP A C   1 
ATOM   4412  O O   . ASP A 1 610 ? 106.579 94.934  109.589 1.00 127.07 ?  599 ASP A O   1 
ATOM   4413  C CB  . ASP A 1 610 ? 107.213 96.532  106.575 1.00 127.07 ?  599 ASP A CB  1 
ATOM   4414  N N   . THR A 1 611 ? 106.857 97.168  109.537 1.00 126.58 ?  600 THR A N   1 
ATOM   4415  C CA  . THR A 1 611 ? 106.125 97.443  110.773 1.00 126.58 ?  600 THR A CA  1 
ATOM   4416  C C   . THR A 1 611 ? 106.678 96.594  111.919 1.00 126.58 ?  600 THR A C   1 
ATOM   4417  O O   . THR A 1 611 ? 106.023 95.699  112.456 1.00 126.58 ?  600 THR A O   1 
ATOM   4418  C CB  . THR A 1 611 ? 104.625 97.224  110.580 1.00 126.58 ?  600 THR A CB  1 
ATOM   4419  N N   . ILE A 1 612 ? 107.934 96.880  112.267 1.00 124.22 ?  601 ILE A N   1 
ATOM   4420  C CA  . ILE A 1 612 ? 108.612 96.125  113.310 1.00 124.22 ?  601 ILE A CA  1 
ATOM   4421  C C   . ILE A 1 612 ? 108.064 96.533  114.674 1.00 124.22 ?  601 ILE A C   1 
ATOM   4422  O O   . ILE A 1 612 ? 107.551 97.646  114.858 1.00 124.22 ?  601 ILE A O   1 
ATOM   4423  C CB  . ILE A 1 612 ? 110.135 96.347  113.221 1.00 124.22 ?  601 ILE A CB  1 
ATOM   4424  C CG1 . ILE A 1 612 ? 110.881 95.418  114.177 1.00 124.22 ?  601 ILE A CG1 1 
ATOM   4425  C CG2 . ILE A 1 612 ? 110.482 97.801  113.504 1.00 124.22 ?  601 ILE A CG2 1 
ATOM   4426  C CD1 . ILE A 1 612 ? 110.566 93.960  113.968 1.00 124.22 ?  601 ILE A CD1 1 
ATOM   4427  N N   . LYS A 1 613 ? 108.156 95.619  115.639 1.00 123.52 ?  602 LYS A N   1 
ATOM   4428  C CA  . LYS A 1 613 ? 107.717 95.922  116.994 1.00 123.52 ?  602 LYS A CA  1 
ATOM   4429  C C   . LYS A 1 613 ? 108.681 96.916  117.636 1.00 123.52 ?  602 LYS A C   1 
ATOM   4430  O O   . LYS A 1 613 ? 109.902 96.727  117.598 1.00 123.52 ?  602 LYS A O   1 
ATOM   4431  C CB  . LYS A 1 613 ? 107.600 94.639  117.822 1.00 123.52 ?  602 LYS A CB  1 
ATOM   4432  N N   . ASP A 1 614 ? 108.134 97.996  118.183 1.00 119.20 ?  603 ASP A N   1 
ATOM   4433  C CA  . ASP A 1 614 ? 108.964 99.017  118.804 1.00 119.20 ?  603 ASP A CA  1 
ATOM   4434  C C   . ASP A 1 614 ? 109.392 98.552  120.190 1.00 119.20 ?  603 ASP A C   1 
ATOM   4435  O O   . ASP A 1 614 ? 108.554 98.247  121.043 1.00 119.20 ?  603 ASP A O   1 
ATOM   4436  C CB  . ASP A 1 614 ? 108.196 100.338 118.884 1.00 119.20 ?  603 ASP A CB  1 
ATOM   4437  N N   . SER A 1 615 ? 110.706 98.494  120.409 1.00 112.73 ?  604 SER A N   1 
ATOM   4438  C CA  . SER A 1 615 ? 111.252 98.018  121.681 1.00 112.73 ?  604 SER A CA  1 
ATOM   4439  C C   . SER A 1 615 ? 112.534 98.806  121.954 1.00 112.73 ?  604 SER A C   1 
ATOM   4440  O O   . SER A 1 615 ? 113.599 98.490  121.420 1.00 112.73 ?  604 SER A O   1 
ATOM   4441  C CB  . SER A 1 615 ? 111.512 96.518  121.649 1.00 112.73 ?  604 SER A CB  1 
ATOM   4442  O OG  . SER A 1 615 ? 112.083 96.075  122.867 1.00 112.73 ?  604 SER A OG  1 
ATOM   4443  N N   . ASP A 1 616 ? 112.413 99.840  122.785 1.00 107.39 ?  605 ASP A N   1 
ATOM   4444  C CA  . ASP A 1 616 ? 113.587 100.589 123.211 1.00 107.39 ?  605 ASP A CA  1 
ATOM   4445  C C   . ASP A 1 616 ? 114.496 99.695  124.042 1.00 107.39 ?  605 ASP A C   1 
ATOM   4446  O O   . ASP A 1 616 ? 114.027 98.909  124.869 1.00 107.39 ?  605 ASP A O   1 
ATOM   4447  C CB  . ASP A 1 616 ? 113.168 101.820 124.016 1.00 107.39 ?  605 ASP A CB  1 
ATOM   4448  C CG  . ASP A 1 616 ? 112.925 103.034 123.140 1.00 107.39 ?  605 ASP A CG  1 
ATOM   4449  O OD1 . ASP A 1 616 ? 113.092 104.168 123.634 1.00 107.39 ?  605 ASP A OD1 1 
ATOM   4450  O OD2 . ASP A 1 616 ? 112.567 102.855 121.958 1.00 107.39 -1 605 ASP A OD2 1 
ATOM   4451  N N   . GLU A 1 617 ? 115.807 99.812  123.815 1.00 96.82  ?  606 GLU A N   1 
ATOM   4452  C CA  . GLU A 1 617 ? 116.749 98.953  124.522 1.00 96.82  ?  606 GLU A CA  1 
ATOM   4453  C C   . GLU A 1 617 ? 116.825 99.300  126.002 1.00 96.82  ?  606 GLU A C   1 
ATOM   4454  O O   . GLU A 1 617 ? 117.079 98.418  126.830 1.00 96.82  ?  606 GLU A O   1 
ATOM   4455  C CB  . GLU A 1 617 ? 118.132 99.048  123.881 1.00 96.82  ?  606 GLU A CB  1 
ATOM   4456  C CG  . GLU A 1 617 ? 119.053 97.895  124.232 1.00 96.82  ?  606 GLU A CG  1 
ATOM   4457  C CD  . GLU A 1 617 ? 120.378 97.970  123.508 1.00 96.82  ?  606 GLU A CD  1 
ATOM   4458  O OE1 . GLU A 1 617 ? 121.156 96.998  123.583 1.00 96.82  ?  606 GLU A OE1 1 
ATOM   4459  O OE2 . GLU A 1 617 ? 120.644 99.004  122.860 1.00 96.82  -1 606 GLU A OE2 1 
ATOM   4460  N N   . GLU A 1 618 ? 116.606 100.567 126.349 1.00 89.43  ?  607 GLU A N   1 
ATOM   4461  C CA  . GLU A 1 618 ? 116.641 101.037 127.733 1.00 89.43  ?  607 GLU A CA  1 
ATOM   4462  C C   . GLU A 1 618 ? 117.970 100.653 128.392 1.00 89.43  ?  607 GLU A C   1 
ATOM   4463  O O   . GLU A 1 618 ? 118.049 99.814  129.287 1.00 89.43  ?  607 GLU A O   1 
ATOM   4464  C CB  . GLU A 1 618 ? 115.432 100.508 128.516 1.00 89.43  ?  607 GLU A CB  1 
ATOM   4465  C CG  . GLU A 1 618 ? 115.300 101.044 129.939 1.00 89.43  ?  607 GLU A CG  1 
ATOM   4466  C CD  . GLU A 1 618 ? 115.465 99.968  130.993 1.00 89.43  ?  607 GLU A CD  1 
ATOM   4467  O OE1 . GLU A 1 618 ? 114.841 98.897  130.852 1.00 89.43  ?  607 GLU A OE1 1 
ATOM   4468  O OE2 . GLU A 1 618 ? 116.213 100.195 131.969 1.00 89.43  -1 607 GLU A OE2 1 
ATOM   4469  N N   . LEU A 1 619 ? 119.026 101.272 127.872 1.00 80.99  ?  608 LEU A N   1 
ATOM   4470  C CA  . LEU A 1 619 ? 120.367 101.041 128.384 1.00 80.99  ?  608 LEU A CA  1 
ATOM   4471  C C   . LEU A 1 619 ? 120.469 101.499 129.834 1.00 80.99  ?  608 LEU A C   1 
ATOM   4472  O O   . LEU A 1 619 ? 119.809 102.453 130.254 1.00 80.99  ?  608 LEU A O   1 
ATOM   4473  C CB  . LEU A 1 619 ? 121.397 101.776 127.529 1.00 80.99  ?  608 LEU A CB  1 
ATOM   4474  C CG  . LEU A 1 619 ? 121.770 101.143 126.188 1.00 80.99  ?  608 LEU A CG  1 
ATOM   4475  C CD1 . LEU A 1 619 ? 120.767 101.517 125.115 1.00 80.99  ?  608 LEU A CD1 1 
ATOM   4476  C CD2 . LEU A 1 619 ? 123.163 101.566 125.781 1.00 80.99  ?  608 LEU A CD2 1 
ATOM   4477  N N   . ASP A 1 620 ? 121.152 100.679 130.631 1.00 73.61  ?  609 ASP A N   1 
ATOM   4478  C CA  . ASP A 1 620 ? 121.300 100.986 132.040 1.00 73.61  ?  609 ASP A CA  1 
ATOM   4479  C C   . ASP A 1 620 ? 122.451 101.934 132.274 1.00 73.61  ?  609 ASP A C   1 
ATOM   4480  O O   . ASP A 1 620 ? 123.203 102.223 131.369 1.00 73.61  ?  609 ASP A O   1 
ATOM   4481  C CB  . ASP A 1 620 ? 121.299 99.748  132.952 1.00 73.61  ?  609 ASP A CB  1 
ATOM   4482  C CG  . ASP A 1 620 ? 122.418 98.784  132.666 1.00 73.61  ?  609 ASP A CG  1 
ATOM   4483  O OD1 . ASP A 1 620 ? 122.107 97.638  132.314 1.00 73.61  ?  609 ASP A OD1 1 
ATOM   4484  O OD2 . ASP A 1 620 ? 123.601 99.133  132.829 1.00 73.61  -1 609 ASP A OD2 1 
ATOM   4485  N N   . ASN A 1 621 ? 122.635 102.344 133.513 1.00 65.86  ?  610 ASN A N   1 
ATOM   4486  C CA  . ASN A 1 621 ? 123.610 103.353 133.852 1.00 65.86  ?  610 ASN A CA  1 
ATOM   4487  C C   . ASN A 1 621 ? 125.031 103.012 133.457 1.00 65.86  ?  610 ASN A C   1 
ATOM   4488  O O   . ASN A 1 621 ? 125.786 103.882 133.080 1.00 65.86  ?  610 ASN A O   1 
ATOM   4489  C CB  . ASN A 1 621 ? 123.524 103.659 135.349 1.00 65.86  ?  610 ASN A CB  1 
ATOM   4490  C CG  . ASN A 1 621 ? 122.174 104.229 135.770 1.00 65.86  ?  610 ASN A CG  1 
ATOM   4491  O OD1 . ASN A 1 621 ? 121.249 104.321 134.988 1.00 65.86  ?  610 ASN A OD1 1 
ATOM   4492  N ND2 . ASN A 1 621 ? 122.069 104.607 137.023 1.00 65.86  ?  610 ASN A ND2 1 
ATOM   4493  N N   . ASN A 1 622 ? 125.417 101.758 133.582 1.00 72.28  ?  611 ASN A N   1 
ATOM   4494  C CA  . ASN A 1 622 ? 126.763 101.357 133.239 1.00 72.28  ?  611 ASN A CA  1 
ATOM   4495  C C   . ASN A 1 622 ? 126.947 100.993 131.764 1.00 72.28  ?  611 ASN A C   1 
ATOM   4496  O O   . ASN A 1 622 ? 128.061 100.732 131.326 1.00 72.28  ?  611 ASN A O   1 
ATOM   4497  C CB  . ASN A 1 622 ? 127.214 100.231 134.163 1.00 72.28  ?  611 ASN A CB  1 
ATOM   4498  C CG  . ASN A 1 622 ? 126.999 100.561 135.637 1.00 72.28  ?  611 ASN A CG  1 
ATOM   4499  O OD1 . ASN A 1 622 ? 126.730 99.675  136.440 1.00 72.28  ?  611 ASN A OD1 1 
ATOM   4500  N ND2 . ASN A 1 622 ? 127.114 101.841 135.995 1.00 72.28  ?  611 ASN A ND2 1 
ATOM   4501  N N   . GLN A 1 623 ? 125.854 100.953 131.005 1.00 72.14  ?  612 GLN A N   1 
ATOM   4502  C CA  . GLN A 1 623 ? 125.912 100.655 129.581 1.00 72.14  ?  612 GLN A CA  1 
ATOM   4503  C C   . GLN A 1 623 ? 125.615 101.858 128.696 1.00 72.14  ?  612 GLN A C   1 
ATOM   4504  O O   . GLN A 1 623 ? 125.918 101.835 127.524 1.00 72.14  ?  612 GLN A O   1 
ATOM   4505  C CB  . GLN A 1 623 ? 124.871 99.589  129.218 1.00 72.14  ?  612 GLN A CB  1 
ATOM   4506  C CG  . GLN A 1 623 ? 125.133 98.195  129.745 1.00 72.14  ?  612 GLN A CG  1 
ATOM   4507  C CD  . GLN A 1 623 ? 123.903 97.308  129.663 1.00 72.14  ?  612 GLN A CD  1 
ATOM   4508  O OE1 . GLN A 1 623 ? 123.961 96.120  129.975 1.00 72.14  ?  612 GLN A OE1 1 
ATOM   4509  N NE2 . GLN A 1 623 ? 122.778 97.886  129.258 1.00 72.14  ?  612 GLN A NE2 1 
ATOM   4510  N N   . ILE A 1 624 ? 125.036 102.909 129.259 1.00 69.10  ?  613 ILE A N   1 
ATOM   4511  C CA  . ILE A 1 624 ? 124.606 104.078 128.479 1.00 69.10  ?  613 ILE A CA  1 
ATOM   4512  C C   . ILE A 1 624 ? 125.660 104.930 127.771 1.00 69.10  ?  613 ILE A C   1 
ATOM   4513  O O   . ILE A 1 624 ? 125.352 105.590 126.801 1.00 69.10  ?  613 ILE A O   1 
ATOM   4514  C CB  . ILE A 1 624 ? 123.584 104.961 129.223 1.00 69.10  ?  613 ILE A CB  1 
ATOM   4515  C CG1 . ILE A 1 624 ? 122.481 105.377 128.251 1.00 69.10  ?  613 ILE A CG1 1 
ATOM   4516  C CG2 . ILE A 1 624 ? 124.254 106.166 129.850 1.00 69.10  ?  613 ILE A CG2 1 
ATOM   4517  C CD1 . ILE A 1 624 ? 121.478 106.350 128.806 1.00 69.10  ?  613 ILE A CD1 1 
ATOM   4518  N N   . GLU A 1 625 ? 126.907 104.871 128.226 1.00 67.47  ?  614 GLU A N   1 
ATOM   4519  C CA  . GLU A 1 625 ? 128.047 105.625 127.680 1.00 67.47  ?  614 GLU A CA  1 
ATOM   4520  C C   . GLU A 1 625 ? 128.459 105.292 126.238 1.00 67.47  ?  614 GLU A C   1 
ATOM   4521  O O   . GLU A 1 625 ? 129.148 106.071 125.588 1.00 67.47  ?  614 GLU A O   1 
ATOM   4522  C CB  . GLU A 1 625 ? 129.265 105.517 128.607 1.00 67.47  ?  614 GLU A CB  1 
ATOM   4523  C CG  . GLU A 1 625 ? 129.771 104.100 128.822 1.00 67.47  ?  614 GLU A CG  1 
ATOM   4524  C CD  . GLU A 1 625 ? 130.996 104.036 129.725 1.00 67.47  ?  614 GLU A CD  1 
ATOM   4525  O OE1 . GLU A 1 625 ? 130.996 104.679 130.794 1.00 67.47  ?  614 GLU A OE1 1 
ATOM   4526  O OE2 . GLU A 1 625 ? 131.966 103.326 129.373 1.00 67.47  -1 614 GLU A OE2 1 
ATOM   4527  N N   . VAL A 1 626 ? 128.037 104.126 125.757 1.00 68.06  ?  615 VAL A N   1 
ATOM   4528  C CA  . VAL A 1 626 ? 128.282 103.611 124.422 1.00 68.06  ?  615 VAL A CA  1 
ATOM   4529  C C   . VAL A 1 626 ? 127.693 104.505 123.307 1.00 68.06  ?  615 VAL A C   1 
ATOM   4530  O O   . VAL A 1 626 ? 128.188 104.504 122.186 1.00 68.06  ?  615 VAL A O   1 
ATOM   4531  C CB  . VAL A 1 626 ? 127.824 102.134 124.333 1.00 68.06  ?  615 VAL A CB  1 
ATOM   4532  C CG1 . VAL A 1 626 ? 126.349 102.009 124.035 1.00 68.06  ?  615 VAL A CG1 1 
ATOM   4533  C CG2 . VAL A 1 626 ? 128.661 101.365 123.341 1.00 68.06  ?  615 VAL A CG2 1 
ATOM   4534  N N   . LEU A 1 627 ? 126.610 105.217 123.593 1.00 65.78  ?  616 LEU A N   1 
ATOM   4535  C CA  . LEU A 1 627 ? 126.017 106.137 122.645 1.00 65.78  ?  616 LEU A CA  1 
ATOM   4536  C C   . LEU A 1 627 ? 126.847 107.404 122.288 1.00 65.78  ?  616 LEU A C   1 
ATOM   4537  O O   . LEU A 1 627 ? 126.509 108.077 121.336 1.00 65.78  ?  616 LEU A O   1 
ATOM   4538  C CB  . LEU A 1 627 ? 124.609 106.517 123.086 1.00 65.78  ?  616 LEU A CB  1 
ATOM   4539  C CG  . LEU A 1 627 ? 123.611 105.419 123.481 1.00 65.78  ?  616 LEU A CG  1 
ATOM   4540  C CD1 . LEU A 1 627 ? 122.265 106.018 123.841 1.00 65.78  ?  616 LEU A CD1 1 
ATOM   4541  C CD2 . LEU A 1 627 ? 123.460 104.337 122.426 1.00 65.78  ?  616 LEU A CD2 1 
ATOM   4542  N N   . ASP A 1 628 ? 127.864 107.797 123.076 1.00 66.98  ?  617 ASP A N   1 
ATOM   4543  C CA  . ASP A 1 628 ? 128.680 108.950 122.727 1.00 66.98  ?  617 ASP A CA  1 
ATOM   4544  C C   . ASP A 1 628 ? 129.908 108.577 121.907 1.00 66.98  ?  617 ASP A C   1 
ATOM   4545  O O   . ASP A 1 628 ? 130.769 109.432 121.683 1.00 66.98  ?  617 ASP A O   1 
ATOM   4546  C CB  . ASP A 1 628 ? 129.113 109.693 123.991 1.00 66.98  ?  617 ASP A CB  1 
ATOM   4547  C CG  . ASP A 1 628 ? 127.959 109.983 124.920 1.00 66.98  ?  617 ASP A CG  1 
ATOM   4548  O OD1 . ASP A 1 628 ? 126.817 109.612 124.583 1.00 66.98  ?  617 ASP A OD1 1 
ATOM   4549  O OD2 . ASP A 1 628 ? 128.189 110.580 125.991 1.00 66.98  -1 617 ASP A OD2 1 
ATOM   4550  N N   . GLN A 1 629 ? 130.007 107.339 121.462 1.00 69.86  ?  618 GLN A N   1 
ATOM   4551  C CA  . GLN A 1 629 ? 131.149 106.865 120.700 1.00 69.86  ?  618 GLN A CA  1 
ATOM   4552  C C   . GLN A 1 629 ? 130.986 107.196 119.221 1.00 69.86  ?  618 GLN A C   1 
ATOM   4553  O O   . GLN A 1 629 ? 129.862 107.305 118.724 1.00 69.86  ?  618 GLN A O   1 
ATOM   4554  C CB  . GLN A 1 629 ? 131.310 105.359 120.870 1.00 69.86  ?  618 GLN A CB  1 
ATOM   4555  C CG  . GLN A 1 629 ? 131.522 104.918 122.305 1.00 69.86  ?  618 GLN A CG  1 
ATOM   4556  C CD  . GLN A 1 629 ? 132.607 105.708 123.005 1.00 69.86  ?  618 GLN A CD  1 
ATOM   4557  O OE1 . GLN A 1 629 ? 133.682 105.938 122.451 1.00 69.86  ?  618 GLN A OE1 1 
ATOM   4558  N NE2 . GLN A 1 629 ? 132.329 106.133 124.233 1.00 69.86  ?  618 GLN A NE2 1 
ATOM   4559  N N   . PRO A 1 630 ? 132.096 107.373 118.506 1.00 71.60  ?  619 PRO A N   1 
ATOM   4560  C CA  . PRO A 1 630 ? 132.008 107.635 117.067 1.00 71.60  ?  619 PRO A CA  1 
ATOM   4561  C C   . PRO A 1 630 ? 131.297 106.507 116.340 1.00 71.60  ?  619 PRO A C   1 
ATOM   4562  O O   . PRO A 1 630 ? 131.417 105.336 116.699 1.00 71.60  ?  619 PRO A O   1 
ATOM   4563  C CB  . PRO A 1 630 ? 133.473 107.744 116.640 1.00 71.60  ?  619 PRO A CB  1 
ATOM   4564  C CG  . PRO A 1 630 ? 134.192 108.135 117.869 1.00 71.60  ?  619 PRO A CG  1 
ATOM   4565  C CD  . PRO A 1 630 ? 133.480 107.462 118.993 1.00 71.60  ?  619 PRO A CD  1 
ATOM   4566  N N   . ILE A 1 631 ? 130.479 106.835 115.360 1.00 77.92  ?  620 ILE A N   1 
ATOM   4567  C CA  . ILE A 1 631 ? 129.739 105.789 114.689 1.00 77.92  ?  620 ILE A CA  1 
ATOM   4568  C C   . ILE A 1 631 ? 130.651 105.099 113.696 1.00 77.92  ?  620 ILE A C   1 
ATOM   4569  O O   . ILE A 1 631 ? 131.077 105.703 112.717 1.00 77.92  ?  620 ILE A O   1 
ATOM   4570  C CB  . ILE A 1 631 ? 128.486 106.331 113.989 1.00 77.92  ?  620 ILE A CB  1 
ATOM   4571  C CG1 . ILE A 1 631 ? 127.431 106.701 115.031 1.00 77.92  ?  620 ILE A CG1 1 
ATOM   4572  C CG2 . ILE A 1 631 ? 127.938 105.307 113.011 1.00 77.92  ?  620 ILE A CG2 1 
ATOM   4573  C CD1 . ILE A 1 631 ? 126.123 107.165 114.437 1.00 77.92  ?  620 ILE A CD1 1 
ATOM   4574  N N   . ASN A 1 632 ? 130.982 103.841 113.960 1.00 93.63  ?  621 ASN A N   1 
ATOM   4575  C CA  . ASN A 1 632 ? 131.809 103.075 113.039 1.00 93.63  ?  621 ASN A CA  1 
ATOM   4576  C C   . ASN A 1 632 ? 130.933 102.084 112.307 1.00 93.63  ?  621 ASN A C   1 
ATOM   4577  O O   . ASN A 1 632 ? 130.651 101.005 112.816 1.00 93.63  ?  621 ASN A O   1 
ATOM   4578  C CB  . ASN A 1 632 ? 132.919 102.348 113.789 1.00 93.63  ?  621 ASN A CB  1 
ATOM   4579  C CG  . ASN A 1 632 ? 133.843 101.577 112.866 1.00 93.63  ?  621 ASN A CG  1 
ATOM   4580  O OD1 . ASN A 1 632 ? 133.618 101.503 111.659 1.00 93.63  ?  621 ASN A OD1 1 
ATOM   4581  N ND2 . ASN A 1 632 ? 134.892 100.998 113.433 1.00 93.63  ?  621 ASN A ND2 1 
ATOM   4582  N N   . THR A 1 633 ? 130.491 102.452 111.114 1.00 100.91 ?  622 THR A N   1 
ATOM   4583  C CA  . THR A 1 633 ? 129.619 101.583 110.342 1.00 100.91 ?  622 THR A CA  1 
ATOM   4584  C C   . THR A 1 633 ? 130.384 100.989 109.173 1.00 100.91 ?  622 THR A C   1 
ATOM   4585  O O   . THR A 1 633 ? 129.785 100.507 108.214 1.00 100.91 ?  622 THR A O   1 
ATOM   4586  C CB  . THR A 1 633 ? 128.393 102.353 109.827 1.00 100.91 ?  622 THR A CB  1 
ATOM   4587  O OG1 . THR A 1 633 ? 127.601 101.498 108.996 1.00 100.91 ?  622 THR A OG1 1 
ATOM   4588  C CG2 . THR A 1 633 ? 128.828 103.566 109.024 1.00 100.91 ?  622 THR A CG2 1 
ATOM   4589  N N   . THR A 1 634 ? 131.709 101.010 109.253 1.00 103.95 ?  623 THR A N   1 
ATOM   4590  C CA  . THR A 1 634 ? 132.529 100.505 108.156 1.00 103.95 ?  623 THR A CA  1 
ATOM   4591  C C   . THR A 1 634 ? 132.250 99.037  107.895 1.00 103.95 ?  623 THR A C   1 
ATOM   4592  O O   . THR A 1 634 ? 132.437 98.556  106.779 1.00 103.95 ?  623 THR A O   1 
ATOM   4593  C CB  . THR A 1 634 ? 134.030 100.694 108.431 1.00 103.95 ?  623 THR A CB  1 
ATOM   4594  O OG1 . THR A 1 634 ? 134.401 99.947  109.596 1.00 103.95 ?  623 THR A OG1 1 
ATOM   4595  C CG2 . THR A 1 634 ? 134.346 102.163 108.652 1.00 103.95 ?  623 THR A CG2 1 
ATOM   4596  N N   . ASP A 1 635 ? 131.807 98.316  108.916 1.00 108.64 ?  624 ASP A N   1 
ATOM   4597  C CA  . ASP A 1 635 ? 131.457 96.917  108.725 1.00 108.64 ?  624 ASP A CA  1 
ATOM   4598  C C   . ASP A 1 635 ? 130.370 96.796  107.674 1.00 108.64 ?  624 ASP A C   1 
ATOM   4599  O O   . ASP A 1 635 ? 130.379 95.867  106.871 1.00 108.64 ?  624 ASP A O   1 
ATOM   4600  C CB  . ASP A 1 635 ? 130.983 96.295  110.036 1.00 108.64 ?  624 ASP A CB  1 
ATOM   4601  C CG  . ASP A 1 635 ? 129.793 97.023  110.635 1.00 108.64 ?  624 ASP A CG  1 
ATOM   4602  O OD1 . ASP A 1 635 ? 129.570 98.201  110.286 1.00 108.64 ?  624 ASP A OD1 1 
ATOM   4603  O OD2 . ASP A 1 635 ? 129.083 96.416  111.461 1.00 108.64 -1 624 ASP A OD2 1 
ATOM   4604  N N   . LEU A 1 636 ? 129.431 97.735  107.671 1.00 110.85 ?  625 LEU A N   1 
ATOM   4605  C CA  . LEU A 1 636 ? 128.334 97.695  106.715 1.00 110.85 ?  625 LEU A CA  1 
ATOM   4606  C C   . LEU A 1 636 ? 128.846 97.967  105.314 1.00 110.85 ?  625 LEU A C   1 
ATOM   4607  O O   . LEU A 1 636 ? 129.777 98.748  105.132 1.00 110.85 ?  625 LEU A O   1 
ATOM   4608  C CB  . LEU A 1 636 ? 127.249 98.699  107.101 1.00 110.85 ?  625 LEU A CB  1 
ATOM   4609  C CG  . LEU A 1 636 ? 126.621 98.474  108.476 1.00 110.85 ?  625 LEU A CG  1 
ATOM   4610  C CD1 . LEU A 1 636 ? 125.389 99.350  108.644 1.00 110.85 ?  625 LEU A CD1 1 
ATOM   4611  C CD2 . LEU A 1 636 ? 126.259 97.008  108.650 1.00 110.85 ?  625 LEU A CD2 1 
ATOM   4612  N N   . PRO A 1 637 ? 128.244 97.317  104.311 1.00 116.07 ?  626 PRO A N   1 
ATOM   4613  C CA  . PRO A 1 637 ? 128.734 97.465  102.937 1.00 116.07 ?  626 PRO A CA  1 
ATOM   4614  C C   . PRO A 1 637 ? 128.465 98.850  102.379 1.00 116.07 ?  626 PRO A C   1 
ATOM   4615  O O   . PRO A 1 637 ? 129.306 99.386  101.660 1.00 116.07 ?  626 PRO A O   1 
ATOM   4616  C CB  . PRO A 1 637 ? 127.915 96.430  102.154 1.00 116.07 ?  626 PRO A CB  1 
ATOM   4617  C CG  . PRO A 1 637 ? 127.221 95.585  103.173 1.00 116.07 ?  626 PRO A CG  1 
ATOM   4618  C CD  . PRO A 1 637 ? 127.067 96.440  104.388 1.00 116.07 ?  626 PRO A CD  1 
ATOM   4619  N N   . PHE A 1 638 ? 127.315 99.424  102.705 1.00 117.07 ?  627 PHE A N   1 
ATOM   4620  C CA  . PHE A 1 638 ? 126.943 100.724 102.168 1.00 117.07 ?  627 PHE A CA  1 
ATOM   4621  C C   . PHE A 1 638 ? 126.988 101.806 103.226 1.00 117.07 ?  627 PHE A C   1 
ATOM   4622  O O   . PHE A 1 638 ? 126.886 101.516 104.417 1.00 117.07 ?  627 PHE A O   1 
ATOM   4623  C CB  . PHE A 1 638 ? 125.533 100.648 101.601 1.00 117.07 ?  627 PHE A CB  1 
ATOM   4624  C CG  . PHE A 1 638 ? 124.523 100.132 102.580 1.00 117.07 ?  627 PHE A CG  1 
ATOM   4625  C CD1 . PHE A 1 638 ? 124.434 98.779  102.851 1.00 117.07 ?  627 PHE A CD1 1 
ATOM   4626  C CD2 . PHE A 1 638 ? 123.669 101.000 103.237 1.00 117.07 ?  627 PHE A CD2 1 
ATOM   4627  C CE1 . PHE A 1 638 ? 123.507 98.296  103.752 1.00 117.07 ?  627 PHE A CE1 1 
ATOM   4628  C CE2 . PHE A 1 638 ? 122.741 100.525 104.140 1.00 117.07 ?  627 PHE A CE2 1 
ATOM   4629  C CZ  . PHE A 1 638 ? 122.661 99.171  104.397 1.00 117.07 ?  627 PHE A CZ  1 
ATOM   4630  N N   . HIS A 1 639 ? 127.140 103.055 102.801 1.00 112.48 ?  628 HIS A N   1 
ATOM   4631  C CA  . HIS A 1 639 ? 127.131 104.165 103.746 1.00 112.48 ?  628 HIS A CA  1 
ATOM   4632  C C   . HIS A 1 639 ? 125.704 104.491 104.141 1.00 112.48 ?  628 HIS A C   1 
ATOM   4633  O O   . HIS A 1 639 ? 124.780 104.289 103.356 1.00 112.48 ?  628 HIS A O   1 
ATOM   4634  C CB  . HIS A 1 639 ? 127.798 105.396 103.140 1.00 112.48 ?  628 HIS A CB  1 
ATOM   4635  N N   . ILE A 1 640 ? 125.517 104.993 105.353 1.00 101.27 ?  629 ILE A N   1 
ATOM   4636  C CA  . ILE A 1 640 ? 124.185 105.365 105.804 1.00 101.27 ?  629 ILE A CA  1 
ATOM   4637  C C   . ILE A 1 640 ? 123.963 106.863 105.692 1.00 101.27 ?  629 ILE A C   1 
ATOM   4638  O O   . ILE A 1 640 ? 124.704 107.643 106.284 1.00 101.27 ?  629 ILE A O   1 
ATOM   4639  C CB  . ILE A 1 640 ? 123.955 104.938 107.263 1.00 101.27 ?  629 ILE A CB  1 
ATOM   4640  C CG1 . ILE A 1 640 ? 123.987 103.414 107.384 1.00 101.27 ?  629 ILE A CG1 1 
ATOM   4641  C CG2 . ILE A 1 640 ? 122.634 105.487 107.781 1.00 101.27 ?  629 ILE A CG2 1 
ATOM   4642  C CD1 . ILE A 1 640 ? 123.740 102.909 108.788 1.00 101.27 ?  629 ILE A CD1 1 
ATOM   4643  N N   . ASP A 1 641 ? 122.962 107.283 104.924 1.00 93.64  ?  630 ASP A N   1 
ATOM   4644  C CA  . ASP A 1 641 ? 122.650 108.708 104.870 1.00 93.64  ?  630 ASP A CA  1 
ATOM   4645  C C   . ASP A 1 641 ? 121.729 109.041 106.035 1.00 93.64  ?  630 ASP A C   1 
ATOM   4646  O O   . ASP A 1 641 ? 120.514 108.852 105.956 1.00 93.64  ?  630 ASP A O   1 
ATOM   4647  C CB  . ASP A 1 641 ? 122.010 109.069 103.535 1.00 93.64  ?  630 ASP A CB  1 
ATOM   4648  C CG  . ASP A 1 641 ? 122.169 110.537 103.190 1.00 93.64  ?  630 ASP A CG  1 
ATOM   4649  O OD1 . ASP A 1 641 ? 123.220 111.115 103.532 1.00 93.64  ?  630 ASP A OD1 1 
ATOM   4650  O OD2 . ASP A 1 641 ? 121.246 111.112 102.577 1.00 93.64  -1 630 ASP A OD2 1 
ATOM   4651  N N   . TRP A 1 642 ? 122.310 109.542 107.124 1.00 83.18  ?  631 TRP A N   1 
ATOM   4652  C CA  . TRP A 1 642 ? 121.548 109.813 108.336 1.00 83.18  ?  631 TRP A CA  1 
ATOM   4653  C C   . TRP A 1 642 ? 120.506 110.903 108.151 1.00 83.18  ?  631 TRP A C   1 
ATOM   4654  O O   . TRP A 1 642 ? 119.612 111.027 108.996 1.00 83.18  ?  631 TRP A O   1 
ATOM   4655  C CB  . TRP A 1 642 ? 122.496 110.193 109.469 1.00 83.18  ?  631 TRP A CB  1 
ATOM   4656  C CG  . TRP A 1 642 ? 123.279 109.040 110.004 1.00 83.18  ?  631 TRP A CG  1 
ATOM   4657  C CD1 . TRP A 1 642 ? 124.618 108.830 109.871 1.00 83.18  ?  631 TRP A CD1 1 
ATOM   4658  C CD2 . TRP A 1 642 ? 122.776 107.936 110.761 1.00 83.18  ?  631 TRP A CD2 1 
ATOM   4659  N NE1 . TRP A 1 642 ? 124.980 107.665 110.494 1.00 83.18  ?  631 TRP A NE1 1 
ATOM   4660  C CE2 . TRP A 1 642 ? 123.865 107.096 111.050 1.00 83.18  ?  631 TRP A CE2 1 
ATOM   4661  C CE3 . TRP A 1 642 ? 121.507 107.576 111.220 1.00 83.18  ?  631 TRP A CE3 1 
ATOM   4662  C CZ2 . TRP A 1 642 ? 123.727 105.920 111.776 1.00 83.18  ?  631 TRP A CZ2 1 
ATOM   4663  C CZ3 . TRP A 1 642 ? 121.373 106.411 111.941 1.00 83.18  ?  631 TRP A CZ3 1 
ATOM   4664  C CH2 . TRP A 1 642 ? 122.475 105.596 112.213 1.00 83.18  ?  631 TRP A CH2 1 
ATOM   4665  N N   . ASN A 1 643 ? 120.592 111.688 107.081 1.00 85.73  ?  632 ASN A N   1 
ATOM   4666  C CA  . ASN A 1 643 ? 119.597 112.707 106.783 1.00 85.73  ?  632 ASN A CA  1 
ATOM   4667  C C   . ASN A 1 643 ? 118.506 112.209 105.847 1.00 85.73  ?  632 ASN A C   1 
ATOM   4668  O O   . ASN A 1 643 ? 117.589 112.972 105.526 1.00 85.73  ?  632 ASN A O   1 
ATOM   4669  C CB  . ASN A 1 643 ? 120.274 113.937 106.174 1.00 85.73  ?  632 ASN A CB  1 
ATOM   4670  C CG  . ASN A 1 643 ? 121.447 114.423 107.002 1.00 85.73  ?  632 ASN A CG  1 
ATOM   4671  O OD1 . ASN A 1 643 ? 121.332 114.616 108.210 1.00 85.73  ?  632 ASN A OD1 1 
ATOM   4672  N ND2 . ASN A 1 643 ? 122.587 114.614 106.353 1.00 85.73  ?  632 ASN A ND2 1 
ATOM   4673  N N   . ASP A 1 644 ? 118.585 110.959 105.404 1.00 93.25  ?  633 ASP A N   1 
ATOM   4674  C CA  . ASP A 1 644 ? 117.560 110.352 104.569 1.00 93.25  ?  633 ASP A CA  1 
ATOM   4675  C C   . ASP A 1 644 ? 116.563 109.619 105.470 1.00 93.25  ?  633 ASP A C   1 
ATOM   4676  O O   . ASP A 1 644 ? 116.578 109.782 106.694 1.00 93.25  ?  633 ASP A O   1 
ATOM   4677  C CB  . ASP A 1 644 ? 118.217 109.438 103.530 1.00 93.25  ?  633 ASP A CB  1 
ATOM   4678  C CG  . ASP A 1 644 ? 117.317 109.158 102.345 1.00 93.25  ?  633 ASP A CG  1 
ATOM   4679  O OD1 . ASP A 1 644 ? 116.578 108.152 102.384 1.00 93.25  ?  633 ASP A OD1 1 
ATOM   4680  O OD2 . ASP A 1 644 ? 117.348 109.941 101.372 1.00 93.25  -1 633 ASP A OD2 1 
ATOM   4681  N N   . ASP A 1 645 ? 115.689 108.808 104.885 1.00 97.50  ?  634 ASP A N   1 
ATOM   4682  C CA  . ASP A 1 645 ? 114.698 108.046 105.631 1.00 97.50  ?  634 ASP A CA  1 
ATOM   4683  C C   . ASP A 1 645 ? 115.296 106.710 106.048 1.00 97.50  ?  634 ASP A C   1 
ATOM   4684  O O   . ASP A 1 645 ? 115.799 105.961 105.203 1.00 97.50  ?  634 ASP A O   1 
ATOM   4685  C CB  . ASP A 1 645 ? 113.435 107.826 104.799 1.00 97.50  ?  634 ASP A CB  1 
ATOM   4686  C CG  . ASP A 1 645 ? 112.483 109.001 104.863 1.00 97.50  ?  634 ASP A CG  1 
ATOM   4687  O OD1 . ASP A 1 645 ? 111.836 109.184 105.915 1.00 97.50  ?  634 ASP A OD1 1 
ATOM   4688  O OD2 . ASP A 1 645 ? 112.379 109.737 103.860 1.00 97.50  -1 634 ASP A OD2 1 
ATOM   4689  N N   . LEU A 1 646 ? 115.245 106.416 107.344 1.00 101.37 ?  635 LEU A N   1 
ATOM   4690  C CA  . LEU A 1 646 ? 115.678 105.115 107.819 1.00 101.37 ?  635 LEU A CA  1 
ATOM   4691  C C   . LEU A 1 646 ? 114.504 104.138 107.813 1.00 101.37 ?  635 LEU A C   1 
ATOM   4692  O O   . LEU A 1 646 ? 113.362 104.523 108.079 1.00 101.37 ?  635 LEU A O   1 
ATOM   4693  C CB  . LEU A 1 646 ? 116.262 105.218 109.224 1.00 101.37 ?  635 LEU A CB  1 
ATOM   4694  C CG  . LEU A 1 646 ? 117.512 106.080 109.382 1.00 101.37 ?  635 LEU A CG  1 
ATOM   4695  C CD1 . LEU A 1 646 ? 118.132 105.834 110.736 1.00 101.37 ?  635 LEU A CD1 1 
ATOM   4696  C CD2 . LEU A 1 646 ? 118.511 105.789 108.280 1.00 101.37 ?  635 LEU A CD2 1 
ATOM   4697  N N   . PRO A 1 647 ? 114.756 102.869 107.508 1.00 107.63 ?  636 PRO A N   1 
ATOM   4698  C CA  . PRO A 1 647 ? 113.657 101.916 107.355 1.00 107.63 ?  636 PRO A CA  1 
ATOM   4699  C C   . PRO A 1 647 ? 113.140 101.420 108.696 1.00 107.63 ?  636 PRO A C   1 
ATOM   4700  O O   . PRO A 1 647 ? 113.771 101.589 109.742 1.00 107.63 ?  636 PRO A O   1 
ATOM   4701  C CB  . PRO A 1 647 ? 114.294 100.777 106.559 1.00 107.63 ?  636 PRO A CB  1 
ATOM   4702  C CG  . PRO A 1 647 ? 115.719 100.802 106.988 1.00 107.63 ?  636 PRO A CG  1 
ATOM   4703  C CD  . PRO A 1 647 ? 116.063 102.254 107.212 1.00 107.63 ?  636 PRO A CD  1 
ATOM   4704  N N   . LEU A 1 648 ? 111.961 100.802 108.643 1.00 111.07 ?  637 LEU A N   1 
ATOM   4705  C CA  . LEU A 1 648 ? 111.372 100.101 109.786 1.00 111.07 ?  637 LEU A CA  1 
ATOM   4706  C C   . LEU A 1 648 ? 111.101 101.047 110.954 1.00 111.07 ?  637 LEU A C   1 
ATOM   4707  O O   . LEU A 1 648 ? 111.456 100.762 112.099 1.00 111.07 ?  637 LEU A O   1 
ATOM   4708  C CB  . LEU A 1 648 ? 112.255 98.931  110.227 1.00 111.07 ?  637 LEU A CB  1 
ATOM   4709  C CG  . LEU A 1 648 ? 112.452 97.813  109.201 1.00 111.07 ?  637 LEU A CG  1 
ATOM   4710  C CD1 . LEU A 1 648 ? 112.916 96.537  109.881 1.00 111.07 ?  637 LEU A CD1 1 
ATOM   4711  C CD2 . LEU A 1 648 ? 111.168 97.570  108.425 1.00 111.07 ?  637 LEU A CD2 1 
ATOM   4712  N N   . ASN A 1 649 ? 110.474 102.184 110.659 1.00 106.26 ?  638 ASN A N   1 
ATOM   4713  C CA  . ASN A 1 649 ? 109.975 103.135 111.649 1.00 106.26 ?  638 ASN A CA  1 
ATOM   4714  C C   . ASN A 1 649 ? 111.076 103.756 112.498 1.00 106.26 ?  638 ASN A C   1 
ATOM   4715  O O   . ASN A 1 649 ? 110.783 104.344 113.546 1.00 106.26 ?  638 ASN A O   1 
ATOM   4716  C CB  . ASN A 1 649 ? 108.926 102.488 112.562 1.00 106.26 ?  638 ASN A CB  1 
ATOM   4717  C CG  . ASN A 1 649 ? 107.734 103.389 112.811 1.00 106.26 ?  638 ASN A CG  1 
ATOM   4718  O OD1 . ASN A 1 649 ? 107.613 104.457 112.210 1.00 106.26 ?  638 ASN A OD1 1 
ATOM   4719  N ND2 . ASN A 1 649 ? 106.844 102.961 113.700 1.00 106.26 ?  638 ASN A ND2 1 
ATOM   4720  N N   . ILE A 1 650 ? 112.339 103.639 112.086 1.00 100.19 ?  639 ILE A N   1 
ATOM   4721  C CA  . ILE A 1 650 ? 113.418 104.270 112.835 1.00 100.19 ?  639 ILE A CA  1 
ATOM   4722  C C   . ILE A 1 650 ? 113.471 105.749 112.491 1.00 100.19 ?  639 ILE A C   1 
ATOM   4723  O O   . ILE A 1 650 ? 113.458 106.131 111.315 1.00 100.19 ?  639 ILE A O   1 
ATOM   4724  C CB  . ILE A 1 650 ? 114.753 103.574 112.540 1.00 100.19 ?  639 ILE A CB  1 
ATOM   4725  C CG1 . ILE A 1 650 ? 114.632 102.069 112.774 1.00 100.19 ?  639 ILE A CG1 1 
ATOM   4726  C CG2 . ILE A 1 650 ? 115.843 104.144 113.409 1.00 100.19 ?  639 ILE A CG2 1 
ATOM   4727  C CD1 . ILE A 1 650 ? 115.824 101.288 112.288 1.00 100.19 ?  639 ILE A CD1 1 
ATOM   4728  N N   . GLU A 1 651 ? 113.532 106.562 113.543 1.00 91.76  ?  640 GLU A N   1 
ATOM   4729  C CA  . GLU A 1 651 ? 113.526 108.000 113.354 1.00 91.76  ?  640 GLU A CA  1 
ATOM   4730  C C   . GLU A 1 651 ? 114.672 108.715 114.049 1.00 91.76  ?  640 GLU A C   1 
ATOM   4731  O O   . GLU A 1 651 ? 114.863 108.565 115.254 1.00 91.76  ?  640 GLU A O   1 
ATOM   4732  C CB  . GLU A 1 651 ? 112.193 108.574 113.841 1.00 91.76  ?  640 GLU A CB  1 
ATOM   4733  C CG  . GLU A 1 651 ? 110.968 107.803 113.374 1.00 91.76  ?  640 GLU A CG  1 
ATOM   4734  C CD  . GLU A 1 651 ? 110.803 107.802 111.866 1.00 91.76  ?  640 GLU A CD  1 
ATOM   4735  O OE1 . GLU A 1 651 ? 111.516 108.565 111.180 1.00 91.76  ?  640 GLU A OE1 1 
ATOM   4736  O OE2 . GLU A 1 651 ? 109.952 107.038 111.365 1.00 91.76  -1 640 GLU A OE2 1 
ATOM   4737  N N   . VAL A 1 652 ? 115.432 109.491 113.296 1.00 83.26  ?  641 VAL A N   1 
ATOM   4738  C CA  . VAL A 1 652 ? 116.543 110.282 113.819 1.00 83.26  ?  641 VAL A CA  1 
ATOM   4739  C C   . VAL A 1 652 ? 116.324 111.725 113.387 1.00 83.26  ?  641 VAL A C   1 
ATOM   4740  O O   . VAL A 1 652 ? 115.811 111.963 112.285 1.00 83.26  ?  641 VAL A O   1 
ATOM   4741  C CB  . VAL A 1 652 ? 117.896 109.755 113.316 1.00 83.26  ?  641 VAL A CB  1 
ATOM   4742  C CG1 . VAL A 1 652 ? 119.029 110.311 114.145 1.00 83.26  ?  641 VAL A CG1 1 
ATOM   4743  C CG2 . VAL A 1 652 ? 117.923 108.254 113.354 1.00 83.26  ?  641 VAL A CG2 1 
ATOM   4744  N N   . PRO A 1 653 ? 116.672 112.713 114.209 1.00 78.36  ?  642 PRO A N   1 
ATOM   4745  C CA  . PRO A 1 653 ? 116.588 114.103 113.753 1.00 78.36  ?  642 PRO A CA  1 
ATOM   4746  C C   . PRO A 1 653 ? 117.526 114.355 112.584 1.00 78.36  ?  642 PRO A C   1 
ATOM   4747  O O   . PRO A 1 653 ? 118.684 113.932 112.588 1.00 78.36  ?  642 PRO A O   1 
ATOM   4748  C CB  . PRO A 1 653 ? 117.006 114.907 114.988 1.00 78.36  ?  642 PRO A CB  1 
ATOM   4749  C CG  . PRO A 1 653 ? 116.727 114.016 116.127 1.00 78.36  ?  642 PRO A CG  1 
ATOM   4750  C CD  . PRO A 1 653 ? 116.977 112.626 115.644 1.00 78.36  ?  642 PRO A CD  1 
ATOM   4751  N N   . LYS A 1 654 ? 117.014 115.047 111.577 1.00 76.71  ?  643 LYS A N   1 
ATOM   4752  C CA  . LYS A 1 654 ? 117.813 115.408 110.422 1.00 76.71  ?  643 LYS A CA  1 
ATOM   4753  C C   . LYS A 1 654 ? 118.348 116.822 110.587 1.00 76.71  ?  643 LYS A C   1 
ATOM   4754  O O   . LYS A 1 654 ? 117.706 117.682 111.194 1.00 76.71  ?  643 LYS A O   1 
ATOM   4755  C CB  . LYS A 1 654 ? 116.991 115.298 109.138 1.00 76.71  ?  643 LYS A CB  1 
ATOM   4756  C CG  . LYS A 1 654 ? 116.224 113.996 109.021 1.00 76.71  ?  643 LYS A CG  1 
ATOM   4757  C CD  . LYS A 1 654 ? 115.314 113.997 107.807 1.00 76.71  ?  643 LYS A CD  1 
ATOM   4758  C CE  . LYS A 1 654 ? 114.496 112.719 107.736 1.00 76.71  ?  643 LYS A CE  1 
ATOM   4759  N NZ  . LYS A 1 654 ? 113.553 112.726 106.585 1.00 76.71  1  643 LYS A NZ  1 
ATOM   4760  N N   . ILE A 1 655 ? 119.540 117.055 110.051 1.00 64.82  ?  644 ILE A N   1 
ATOM   4761  C CA  . ILE A 1 655 ? 120.192 118.352 110.135 1.00 64.82  ?  644 ILE A CA  1 
ATOM   4762  C C   . ILE A 1 655 ? 120.617 118.778 108.740 1.00 64.82  ?  644 ILE A C   1 
ATOM   4763  O O   . ILE A 1 655 ? 120.995 117.943 107.912 1.00 64.82  ?  644 ILE A O   1 
ATOM   4764  C CB  . ILE A 1 655 ? 121.401 118.323 111.094 1.00 64.82  ?  644 ILE A CB  1 
ATOM   4765  C CG1 . ILE A 1 655 ? 122.425 117.288 110.647 1.00 64.82  ?  644 ILE A CG1 1 
ATOM   4766  C CG2 . ILE A 1 655 ? 120.951 118.024 112.503 1.00 64.82  ?  644 ILE A CG2 1 
ATOM   4767  C CD1 . ILE A 1 655 ? 123.730 117.390 111.381 1.00 64.82  ?  644 ILE A CD1 1 
ATOM   4768  N N   . SER A 1 656 ? 120.534 120.079 108.477 1.00 60.48  ?  645 SER A N   1 
ATOM   4769  C CA  . SER A 1 656 ? 121.017 120.635 107.222 1.00 60.48  ?  645 SER A CA  1 
ATOM   4770  C C   . SER A 1 656 ? 122.475 121.052 107.305 1.00 60.48  ?  645 SER A C   1 
ATOM   4771  O O   . SER A 1 656 ? 123.131 121.177 106.268 1.00 60.48  ?  645 SER A O   1 
ATOM   4772  C CB  . SER A 1 656 ? 120.163 121.834 106.815 1.00 60.48  ?  645 SER A CB  1 
ATOM   4773  O OG  . SER A 1 656 ? 118.784 121.518 106.871 1.00 60.48  ?  645 SER A OG  1 
ATOM   4774  N N   . LEU A 1 657 ? 122.989 121.258 108.513 1.00 52.71  ?  646 LEU A N   1 
ATOM   4775  C CA  . LEU A 1 657 ? 124.351 121.733 108.694 1.00 52.71  ?  646 LEU A CA  1 
ATOM   4776  C C   . LEU A 1 657 ? 125.352 120.667 108.273 1.00 52.71  ?  646 LEU A C   1 
ATOM   4777  O O   . LEU A 1 657 ? 125.292 119.526 108.736 1.00 52.71  ?  646 LEU A O   1 
ATOM   4778  C CB  . LEU A 1 657 ? 124.572 122.120 110.154 1.00 52.71  ?  646 LEU A CB  1 
ATOM   4779  C CG  . LEU A 1 657 ? 125.866 122.829 110.534 1.00 52.71  ?  646 LEU A CG  1 
ATOM   4780  C CD1 . LEU A 1 657 ? 125.897 124.200 109.938 1.00 52.71  ?  646 LEU A CD1 1 
ATOM   4781  C CD2 . LEU A 1 657 ? 126.000 122.910 112.033 1.00 52.71  ?  646 LEU A CD2 1 
ATOM   4782  N N   . HIS A 1 658 ? 126.274 121.042 107.388 1.00 53.96  ?  647 HIS A N   1 
ATOM   4783  C CA  . HIS A 1 658 ? 127.401 120.191 107.052 1.00 53.96  ?  647 HIS A CA  1 
ATOM   4784  C C   . HIS A 1 658 ? 128.736 120.897 107.203 1.00 53.96  ?  647 HIS A C   1 
ATOM   4785  O O   . HIS A 1 658 ? 129.772 120.283 106.935 1.00 53.96  ?  647 HIS A O   1 
ATOM   4786  C CB  . HIS A 1 658 ? 127.272 119.648 105.620 1.00 53.96  ?  647 HIS A CB  1 
ATOM   4787  C CG  . HIS A 1 658 ? 127.171 120.707 104.567 1.00 53.96  ?  647 HIS A CG  1 
ATOM   4788  N ND1 . HIS A 1 658 ? 128.205 121.569 104.274 1.00 53.96  ?  647 HIS A ND1 1 
ATOM   4789  C CD2 . HIS A 1 658 ? 126.165 121.029 103.721 1.00 53.96  ?  647 HIS A CD2 1 
ATOM   4790  C CE1 . HIS A 1 658 ? 127.836 122.385 103.305 1.00 53.96  ?  647 HIS A CE1 1 
ATOM   4791  N NE2 . HIS A 1 658 ? 126.602 122.076 102.950 1.00 53.96  ?  647 HIS A NE2 1 
ATOM   4792  N N   . SER A 1 659 ? 128.745 122.158 107.625 1.00 49.06  ?  648 SER A N   1 
ATOM   4793  C CA  . SER A 1 659 ? 129.973 122.928 107.754 1.00 49.06  ?  648 SER A CA  1 
ATOM   4794  C C   . SER A 1 659 ? 129.751 124.031 108.770 1.00 49.06  ?  648 SER A C   1 
ATOM   4795  O O   . SER A 1 659 ? 128.767 124.766 108.677 1.00 49.06  ?  648 SER A O   1 
ATOM   4796  C CB  . SER A 1 659 ? 130.391 123.522 106.411 1.00 49.06  ?  648 SER A CB  1 
ATOM   4797  O OG  . SER A 1 659 ? 130.986 122.541 105.588 1.00 49.06  ?  648 SER A OG  1 
ATOM   4798  N N   . LEU A 1 660 ? 130.658 124.147 109.730 1.00 43.58  ?  649 LEU A N   1 
ATOM   4799  C CA  . LEU A 1 660 ? 130.542 125.122 110.804 1.00 43.58  ?  649 LEU A CA  1 
ATOM   4800  C C   . LEU A 1 660 ? 131.825 125.934 110.871 1.00 43.58  ?  649 LEU A C   1 
ATOM   4801  O O   . LEU A 1 660 ? 132.902 125.379 111.101 1.00 43.58  ?  649 LEU A O   1 
ATOM   4802  C CB  . LEU A 1 660 ? 130.273 124.437 112.142 1.00 43.58  ?  649 LEU A CB  1 
ATOM   4803  C CG  . LEU A 1 660 ? 130.325 125.344 113.367 1.00 43.58  ?  649 LEU A CG  1 
ATOM   4804  C CD1 . LEU A 1 660 ? 129.023 126.088 113.530 1.00 43.58  ?  649 LEU A CD1 1 
ATOM   4805  C CD2 . LEU A 1 660 ? 130.647 124.546 114.605 1.00 43.58  ?  649 LEU A CD2 1 
ATOM   4806  N N   . ILE A 1 661 ? 131.709 127.239 110.668 1.00 41.08  ?  650 ILE A N   1 
ATOM   4807  C CA  . ILE A 1 661 ? 132.842 128.149 110.737 1.00 41.08  ?  650 ILE A CA  1 
ATOM   4808  C C   . ILE A 1 661 ? 132.755 128.898 112.056 1.00 41.08  ?  650 ILE A C   1 
ATOM   4809  O O   . ILE A 1 661 ? 131.680 129.373 112.436 1.00 41.08  ?  650 ILE A O   1 
ATOM   4810  C CB  . ILE A 1 661 ? 132.855 129.116 109.546 1.00 41.08  ?  650 ILE A CB  1 
ATOM   4811  C CG1 . ILE A 1 661 ? 133.058 128.345 108.247 1.00 41.08  ?  650 ILE A CG1 1 
ATOM   4812  C CG2 . ILE A 1 661 ? 133.941 130.148 109.705 1.00 41.08  ?  650 ILE A CG2 1 
ATOM   4813  C CD1 . ILE A 1 661 ? 132.958 129.197 107.042 1.00 41.08  ?  650 ILE A CD1 1 
ATOM   4814  N N   . LEU A 1 662 ? 133.874 128.986 112.765 1.00 40.35  ?  651 LEU A N   1 
ATOM   4815  C CA  . LEU A 1 662 ? 133.954 129.703 114.030 1.00 40.35  ?  651 LEU A CA  1 
ATOM   4816  C C   . LEU A 1 662 ? 134.890 130.889 113.844 1.00 40.35  ?  651 LEU A C   1 
ATOM   4817  O O   . LEU A 1 662 ? 136.098 130.710 113.672 1.00 40.35  ?  651 LEU A O   1 
ATOM   4818  C CB  . LEU A 1 662 ? 134.443 128.790 115.151 1.00 40.35  ?  651 LEU A CB  1 
ATOM   4819  C CG  . LEU A 1 662 ? 133.596 127.571 115.505 1.00 40.35  ?  651 LEU A CG  1 
ATOM   4820  C CD1 . LEU A 1 662 ? 134.382 126.658 116.409 1.00 40.35  ?  651 LEU A CD1 1 
ATOM   4821  C CD2 . LEU A 1 662 ? 132.306 127.984 116.172 1.00 40.35  ?  651 LEU A CD2 1 
ATOM   4822  N N   . ASP A 1 663 ? 134.333 132.095 113.881 1.00 43.45  ?  652 ASP A N   1 
ATOM   4823  C CA  . ASP A 1 663 ? 135.107 133.319 113.696 1.00 43.45  ?  652 ASP A CA  1 
ATOM   4824  C C   . ASP A 1 663 ? 135.811 133.647 115.006 1.00 43.45  ?  652 ASP A C   1 
ATOM   4825  O O   . ASP A 1 663 ? 135.279 134.368 115.851 1.00 43.45  ?  652 ASP A O   1 
ATOM   4826  C CB  . ASP A 1 663 ? 134.203 134.458 113.244 1.00 43.45  ?  652 ASP A CB  1 
ATOM   4827  C CG  . ASP A 1 663 ? 134.950 135.756 113.057 1.00 43.45  ?  652 ASP A CG  1 
ATOM   4828  O OD1 . ASP A 1 663 ? 136.146 135.710 112.705 1.00 43.45  ?  652 ASP A OD1 1 
ATOM   4829  O OD2 . ASP A 1 663 ? 134.340 136.827 113.251 1.00 43.45  -1 652 ASP A OD2 1 
ATOM   4830  N N   . PHE A 1 664 ? 137.025 133.122 115.174 1.00 41.08  ?  653 PHE A N   1 
ATOM   4831  C CA  . PHE A 1 664 ? 137.810 133.293 116.389 1.00 41.08  ?  653 PHE A CA  1 
ATOM   4832  C C   . PHE A 1 664 ? 138.730 134.503 116.309 1.00 41.08  ?  653 PHE A C   1 
ATOM   4833  O O   . PHE A 1 664 ? 139.786 134.521 116.945 1.00 41.08  ?  653 PHE A O   1 
ATOM   4834  C CB  . PHE A 1 664 ? 138.624 132.032 116.670 1.00 41.08  ?  653 PHE A CB  1 
ATOM   4835  C CG  . PHE A 1 664 ? 137.965 131.075 117.617 1.00 41.08  ?  653 PHE A CG  1 
ATOM   4836  C CD1 . PHE A 1 664 ? 136.595 130.912 117.624 1.00 41.08  ?  653 PHE A CD1 1 
ATOM   4837  C CD2 . PHE A 1 664 ? 138.723 130.330 118.497 1.00 41.08  ?  653 PHE A CD2 1 
ATOM   4838  C CE1 . PHE A 1 664 ? 135.999 130.031 118.493 1.00 41.08  ?  653 PHE A CE1 1 
ATOM   4839  C CE2 . PHE A 1 664 ? 138.128 129.450 119.364 1.00 41.08  ?  653 PHE A CE2 1 
ATOM   4840  C CZ  . PHE A 1 664 ? 136.766 129.300 119.361 1.00 41.08  ?  653 PHE A CZ  1 
ATOM   4841  N N   . SER A 1 665 ? 138.343 135.519 115.538 1.00 41.67  ?  654 SER A N   1 
ATOM   4842  C CA  . SER A 1 665 ? 139.219 136.662 115.311 1.00 41.67  ?  654 SER A CA  1 
ATOM   4843  C C   . SER A 1 665 ? 139.365 137.518 116.560 1.00 41.67  ?  654 SER A C   1 
ATOM   4844  O O   . SER A 1 665 ? 140.480 137.908 116.922 1.00 41.67  ?  654 SER A O   1 
ATOM   4845  C CB  . SER A 1 665 ? 138.694 137.496 114.150 1.00 41.67  ?  654 SER A CB  1 
ATOM   4846  O OG  . SER A 1 665 ? 137.694 138.393 114.591 1.00 41.67  ?  654 SER A OG  1 
ATOM   4847  N N   . ALA A 1 666 ? 138.258 137.824 117.229 1.00 40.18  ?  655 ALA A N   1 
ATOM   4848  C CA  . ALA A 1 666 ? 138.286 138.641 118.433 1.00 40.18  ?  655 ALA A CA  1 
ATOM   4849  C C   . ALA A 1 666 ? 138.473 137.827 119.699 1.00 40.18  ?  655 ALA A C   1 
ATOM   4850  O O   . ALA A 1 666 ? 138.436 138.394 120.791 1.00 40.18  ?  655 ALA A O   1 
ATOM   4851  C CB  . ALA A 1 666 ? 137.005 139.469 118.547 1.00 40.18  ?  655 ALA A CB  1 
ATOM   4852  N N   . VAL A 1 667 ? 138.665 136.515 119.584 1.00 41.85  ?  656 VAL A N   1 
ATOM   4853  C CA  . VAL A 1 667 ? 138.930 135.665 120.741 1.00 41.85  ?  656 VAL A CA  1 
ATOM   4854  C C   . VAL A 1 667 ? 140.413 135.807 121.065 1.00 41.85  ?  656 VAL A C   1 
ATOM   4855  O O   . VAL A 1 667 ? 141.271 135.292 120.352 1.00 41.85  ?  656 VAL A O   1 
ATOM   4856  C CB  . VAL A 1 667 ? 138.538 134.210 120.489 1.00 41.85  ?  656 VAL A CB  1 
ATOM   4857  C CG1 . VAL A 1 667 ? 139.010 133.344 121.624 1.00 41.85  ?  656 VAL A CG1 1 
ATOM   4858  C CG2 . VAL A 1 667 ? 137.040 134.095 120.330 1.00 41.85  ?  656 VAL A CG2 1 
ATOM   4859  N N   . SER A 1 668 ? 140.714 136.514 122.152 1.00 43.28  ?  657 SER A N   1 
ATOM   4860  C CA  . SER A 1 668 ? 142.092 136.851 122.485 1.00 43.28  ?  657 SER A CA  1 
ATOM   4861  C C   . SER A 1 668 ? 142.859 135.637 122.999 1.00 43.28  ?  657 SER A C   1 
ATOM   4862  O O   . SER A 1 668 ? 143.861 135.227 122.406 1.00 43.28  ?  657 SER A O   1 
ATOM   4863  C CB  . SER A 1 668 ? 142.112 137.976 123.515 1.00 43.28  ?  657 SER A CB  1 
ATOM   4864  O OG  . SER A 1 668 ? 141.621 139.174 122.946 1.00 43.28  ?  657 SER A OG  1 
ATOM   4865  N N   . PHE A 1 669 ? 142.407 135.051 124.101 1.00 42.37  ?  658 PHE A N   1 
ATOM   4866  C CA  . PHE A 1 669 ? 143.104 133.928 124.703 1.00 42.37  ?  658 PHE A CA  1 
ATOM   4867  C C   . PHE A 1 669 ? 142.136 132.789 124.985 1.00 42.37  ?  658 PHE A C   1 
ATOM   4868  O O   . PHE A 1 669 ? 140.919 132.926 124.860 1.00 42.37  ?  658 PHE A O   1 
ATOM   4869  C CB  . PHE A 1 669 ? 143.833 134.338 125.995 1.00 42.37  ?  658 PHE A CB  1 
ATOM   4870  C CG  . PHE A 1 669 ? 142.953 134.989 127.024 1.00 42.37  ?  658 PHE A CG  1 
ATOM   4871  C CD1 . PHE A 1 669 ? 142.225 134.230 127.921 1.00 42.37  ?  658 PHE A CD1 1 
ATOM   4872  C CD2 . PHE A 1 669 ? 142.877 136.362 127.111 1.00 42.37  ?  658 PHE A CD2 1 
ATOM   4873  C CE1 . PHE A 1 669 ? 141.427 134.828 128.867 1.00 42.37  ?  658 PHE A CE1 1 
ATOM   4874  C CE2 . PHE A 1 669 ? 142.078 136.961 128.056 1.00 42.37  ?  658 PHE A CE2 1 
ATOM   4875  C CZ  . PHE A 1 669 ? 141.355 136.193 128.937 1.00 42.37  ?  658 PHE A CZ  1 
ATOM   4876  N N   . LEU A 1 670 ? 142.697 131.652 125.357 1.00 45.64  ?  659 LEU A N   1 
ATOM   4877  C CA  . LEU A 1 670 ? 141.946 130.461 125.690 1.00 45.64  ?  659 LEU A CA  1 
ATOM   4878  C C   . LEU A 1 670 ? 142.674 129.819 126.855 1.00 45.64  ?  659 LEU A C   1 
ATOM   4879  O O   . LEU A 1 670 ? 143.869 129.589 126.775 1.00 45.64  ?  659 LEU A O   1 
ATOM   4880  C CB  . LEU A 1 670 ? 141.937 129.499 124.504 1.00 45.64  ?  659 LEU A CB  1 
ATOM   4881  C CG  . LEU A 1 670 ? 140.677 129.201 123.692 1.00 45.64  ?  659 LEU A CG  1 
ATOM   4882  C CD1 . LEU A 1 670 ? 140.104 130.423 123.009 1.00 45.64  ?  659 LEU A CD1 1 
ATOM   4883  C CD2 . LEU A 1 670 ? 140.979 128.132 122.662 1.00 45.64  ?  659 LEU A CD2 1 
ATOM   4884  N N   . ASP A 1 671 ? 141.986 129.589 127.962 1.00 45.81  ?  660 ASP A N   1 
ATOM   4885  C CA  . ASP A 1 671 ? 142.604 128.930 129.107 1.00 45.81  ?  660 ASP A CA  1 
ATOM   4886  C C   . ASP A 1 671 ? 142.359 127.432 129.045 1.00 45.81  ?  660 ASP A C   1 
ATOM   4887  O O   . ASP A 1 671 ? 141.847 126.948 128.052 1.00 45.81  ?  660 ASP A O   1 
ATOM   4888  C CB  . ASP A 1 671 ? 142.175 129.553 130.430 1.00 45.81  ?  660 ASP A CB  1 
ATOM   4889  C CG  . ASP A 1 671 ? 140.767 129.235 130.791 1.00 45.81  ?  660 ASP A CG  1 
ATOM   4890  O OD1 . ASP A 1 671 ? 140.096 128.556 130.006 1.00 45.81  ?  660 ASP A OD1 1 
ATOM   4891  O OD2 . ASP A 1 671 ? 140.334 129.654 131.870 1.00 45.81  -1 660 ASP A OD2 1 
ATOM   4892  N N   . VAL A 1 672 ? 142.771 126.682 130.062 1.00 45.61  ?  661 VAL A N   1 
ATOM   4893  C CA  . VAL A 1 672 ? 142.637 125.222 130.022 1.00 45.61  ?  661 VAL A CA  1 
ATOM   4894  C C   . VAL A 1 672 ? 141.182 124.765 130.078 1.00 45.61  ?  661 VAL A C   1 
ATOM   4895  O O   . VAL A 1 672 ? 140.812 123.802 129.425 1.00 45.61  ?  661 VAL A O   1 
ATOM   4896  C CB  . VAL A 1 672 ? 143.443 124.523 131.147 1.00 45.61  ?  661 VAL A CB  1 
ATOM   4897  C CG1 . VAL A 1 672 ? 144.919 124.856 131.035 1.00 45.61  ?  661 VAL A CG1 1 
ATOM   4898  C CG2 . VAL A 1 672 ? 142.896 124.876 132.519 1.00 45.61  ?  661 VAL A CG2 1 
ATOM   4899  N N   . SER A 1 673 ? 140.359 125.457 130.849 1.00 46.19  ?  662 SER A N   1 
ATOM   4900  C CA  . SER A 1 673 ? 138.951 125.118 130.915 1.00 46.19  ?  662 SER A CA  1 
ATOM   4901  C C   . SER A 1 673 ? 138.299 125.309 129.559 1.00 46.19  ?  662 SER A C   1 
ATOM   4902  O O   . SER A 1 673 ? 137.509 124.480 129.122 1.00 46.19  ?  662 SER A O   1 
ATOM   4903  C CB  . SER A 1 673 ? 138.253 125.991 131.952 1.00 46.19  ?  662 SER A CB  1 
ATOM   4904  O OG  . SER A 1 673 ? 138.890 125.906 133.212 1.00 46.19  ?  662 SER A OG  1 
ATOM   4905  N N   . SER A 1 674 ? 138.640 126.393 128.881 1.00 45.21  ?  663 SER A N   1 
ATOM   4906  C CA  . SER A 1 674 ? 138.043 126.681 127.582 1.00 45.21  ?  663 SER A CA  1 
ATOM   4907  C C   . SER A 1 674 ? 138.505 125.711 126.490 1.00 45.21  ?  663 SER A C   1 
ATOM   4908  O O   . SER A 1 674 ? 137.713 125.315 125.650 1.00 45.21  ?  663 SER A O   1 
ATOM   4909  C CB  . SER A 1 674 ? 138.324 128.133 127.175 1.00 45.21  ?  663 SER A CB  1 
ATOM   4910  O OG  . SER A 1 674 ? 139.711 128.406 127.151 1.00 45.21  ?  663 SER A OG  1 
ATOM   4911  N N   . VAL A 1 675 ? 139.776 125.330 126.506 1.00 48.82  ?  664 VAL A N   1 
ATOM   4912  C CA  . VAL A 1 675 ? 140.271 124.390 125.513 1.00 48.82  ?  664 VAL A CA  1 
ATOM   4913  C C   . VAL A 1 675 ? 139.612 123.033 125.711 1.00 48.82  ?  664 VAL A C   1 
ATOM   4914  O O   . VAL A 1 675 ? 139.294 122.355 124.741 1.00 48.82  ?  664 VAL A O   1 
ATOM   4915  C CB  . VAL A 1 675 ? 141.815 124.273 125.511 1.00 48.82  ?  664 VAL A CB  1 
ATOM   4916  C CG1 . VAL A 1 675 ? 142.452 125.630 125.263 1.00 48.82  ?  664 VAL A CG1 1 
ATOM   4917  C CG2 . VAL A 1 675 ? 142.322 123.667 126.807 1.00 48.82  ?  664 VAL A CG2 1 
ATOM   4918  N N   . ARG A 1 676 ? 139.385 122.642 126.955 1.00 49.14  ?  665 ARG A N   1 
ATOM   4919  C CA  . ARG A 1 676 ? 138.717 121.381 127.218 1.00 49.14  ?  665 ARG A CA  1 
ATOM   4920  C C   . ARG A 1 676 ? 137.300 121.425 126.676 1.00 49.14  ?  665 ARG A C   1 
ATOM   4921  O O   . ARG A 1 676 ? 136.888 120.531 125.951 1.00 49.14  ?  665 ARG A O   1 
ATOM   4922  C CB  . ARG A 1 676 ? 138.721 121.063 128.713 1.00 49.14  ?  665 ARG A CB  1 
ATOM   4923  C CG  . ARG A 1 676 ? 140.094 120.773 129.290 1.00 49.14  ?  665 ARG A CG  1 
ATOM   4924  C CD  . ARG A 1 676 ? 139.980 120.263 130.716 1.00 49.14  ?  665 ARG A CD  1 
ATOM   4925  N NE  . ARG A 1 676 ? 141.277 119.927 131.297 1.00 49.14  ?  665 ARG A NE  1 
ATOM   4926  C CZ  . ARG A 1 676 ? 141.960 120.721 132.114 1.00 49.14  ?  665 ARG A CZ  1 
ATOM   4927  N NH1 . ARG A 1 676 ? 141.471 121.903 132.457 1.00 49.14  1  665 ARG A NH1 1 
ATOM   4928  N NH2 . ARG A 1 676 ? 143.133 120.329 132.595 1.00 49.14  ?  665 ARG A NH2 1 
ATOM   4929  N N   . GLY A 1 677 ? 136.557 122.468 127.015 1.00 48.18  ?  666 GLY A N   1 
ATOM   4930  C CA  . GLY A 1 677 ? 135.209 122.616 126.512 1.00 48.18  ?  666 GLY A CA  1 
ATOM   4931  C C   . GLY A 1 677 ? 135.165 122.693 125.007 1.00 48.18  ?  666 GLY A C   1 
ATOM   4932  O O   . GLY A 1 677 ? 134.339 122.043 124.386 1.00 48.18  ?  666 GLY A O   1 
ATOM   4933  N N   . LEU A 1 678 ? 136.058 123.470 124.411 1.00 50.28  ?  667 LEU A N   1 
ATOM   4934  C CA  . LEU A 1 678 ? 136.109 123.588 122.957 1.00 50.28  ?  667 LEU A CA  1 
ATOM   4935  C C   . LEU A 1 678 ? 136.429 122.267 122.285 1.00 50.28  ?  667 LEU A C   1 
ATOM   4936  O O   . LEU A 1 678 ? 135.770 121.891 121.327 1.00 50.28  ?  667 LEU A O   1 
ATOM   4937  C CB  . LEU A 1 678 ? 137.120 124.657 122.538 1.00 50.28  ?  667 LEU A CB  1 
ATOM   4938  C CG  . LEU A 1 678 ? 136.589 126.086 122.618 1.00 50.28  ?  667 LEU A CG  1 
ATOM   4939  C CD1 . LEU A 1 678 ? 137.716 127.099 122.493 1.00 50.28  ?  667 LEU A CD1 1 
ATOM   4940  C CD2 . LEU A 1 678 ? 135.536 126.308 121.547 1.00 50.28  ?  667 LEU A CD2 1 
ATOM   4941  N N   . LYS A 1 679 ? 137.432 121.562 122.783 1.00 50.49  ?  668 LYS A N   1 
ATOM   4942  C CA  . LYS A 1 679 ? 137.779 120.262 122.238 1.00 50.49  ?  668 LYS A CA  1 
ATOM   4943  C C   . LYS A 1 679 ? 136.581 119.341 122.276 1.00 50.49  ?  668 LYS A C   1 
ATOM   4944  O O   . LYS A 1 679 ? 136.337 118.603 121.333 1.00 50.49  ?  668 LYS A O   1 
ATOM   4945  C CB  . LYS A 1 679 ? 138.925 119.650 123.039 1.00 30.00  ?  668 LYS A CB  1 
ATOM   4946  C CG  . LYS A 1 679 ? 139.353 118.267 122.586 1.00 30.00  ?  668 LYS A CG  1 
ATOM   4947  C CD  . LYS A 1 679 ? 139.992 118.307 121.212 1.00 30.00  ?  668 LYS A CD  1 
ATOM   4948  C CE  . LYS A 1 679 ? 140.645 116.976 120.881 1.00 30.00  ?  668 LYS A CE  1 
ATOM   4949  N NZ  . LYS A 1 679 ? 141.752 116.657 121.822 1.00 30.00  1  668 LYS A NZ  1 
ATOM   4950  N N   . SER A 1 680 ? 135.824 119.397 123.359 1.00 50.49  ?  669 SER A N   1 
ATOM   4951  C CA  . SER A 1 680 ? 134.635 118.571 123.486 1.00 50.49  ?  669 SER A CA  1 
ATOM   4952  C C   . SER A 1 680 ? 133.581 118.944 122.447 1.00 50.49  ?  669 SER A C   1 
ATOM   4953  O O   . SER A 1 680 ? 133.091 118.077 121.737 1.00 50.49  ?  669 SER A O   1 
ATOM   4954  C CB  . SER A 1 680 ? 134.078 118.685 124.903 1.00 50.49  ?  669 SER A CB  1 
ATOM   4955  O OG  . SER A 1 680 ? 132.828 118.034 125.016 1.00 50.49  ?  669 SER A OG  1 
ATOM   4956  N N   . ILE A 1 681 ? 133.241 120.225 122.340 1.00 50.84  ?  670 ILE A N   1 
ATOM   4957  C CA  . ILE A 1 681 ? 132.275 120.669 121.341 1.00 50.84  ?  670 ILE A CA  1 
ATOM   4958  C C   . ILE A 1 681 ? 132.671 120.242 119.936 1.00 50.84  ?  670 ILE A C   1 
ATOM   4959  O O   . ILE A 1 681 ? 131.851 119.717 119.195 1.00 50.84  ?  670 ILE A O   1 
ATOM   4960  C CB  . ILE A 1 681 ? 132.128 122.205 121.349 1.00 50.84  ?  670 ILE A CB  1 
ATOM   4961  C CG1 . ILE A 1 681 ? 131.892 122.717 122.768 1.00 50.84  ?  670 ILE A CG1 1 
ATOM   4962  C CG2 . ILE A 1 681 ? 130.996 122.638 120.432 1.00 50.84  ?  670 ILE A CG2 1 
ATOM   4963  C CD1 . ILE A 1 681 ? 131.918 124.225 122.884 1.00 50.84  ?  670 ILE A CD1 1 
ATOM   4964  N N   . LEU A 1 682 ? 133.923 120.469 119.567 1.00 52.77  ?  671 LEU A N   1 
ATOM   4965  C CA  . LEU A 1 682 ? 134.387 120.136 118.224 1.00 52.77  ?  671 LEU A CA  1 
ATOM   4966  C C   . LEU A 1 682 ? 134.350 118.644 117.933 1.00 52.77  ?  671 LEU A C   1 
ATOM   4967  O O   . LEU A 1 682 ? 133.942 118.237 116.854 1.00 52.77  ?  671 LEU A O   1 
ATOM   4968  C CB  . LEU A 1 682 ? 135.799 120.684 118.004 1.00 52.77  ?  671 LEU A CB  1 
ATOM   4969  C CG  . LEU A 1 682 ? 135.934 122.116 117.489 1.00 52.77  ?  671 LEU A CG  1 
ATOM   4970  C CD1 . LEU A 1 682 ? 134.945 123.047 118.169 1.00 52.77  ?  671 LEU A CD1 1 
ATOM   4971  C CD2 . LEU A 1 682 ? 137.356 122.604 117.700 1.00 52.77  ?  671 LEU A CD2 1 
ATOM   4972  N N   . GLN A 1 683 ? 134.773 117.826 118.887 1.00 54.22  ?  672 GLN A N   1 
ATOM   4973  C CA  . GLN A 1 683 ? 134.709 116.383 118.709 1.00 54.22  ?  672 GLN A CA  1 
ATOM   4974  C C   . GLN A 1 683 ? 133.291 115.916 118.434 1.00 54.22  ?  672 GLN A C   1 
ATOM   4975  O O   . GLN A 1 683 ? 133.074 115.040 117.612 1.00 54.22  ?  672 GLN A O   1 
ATOM   4976  C CB  . GLN A 1 683 ? 135.262 115.666 119.934 1.00 54.22  ?  672 GLN A CB  1 
ATOM   4977  C CG  . GLN A 1 683 ? 136.772 115.721 120.055 1.00 54.22  ?  672 GLN A CG  1 
ATOM   4978  C CD  . GLN A 1 683 ? 137.270 115.075 121.329 1.00 54.22  ?  672 GLN A CD  1 
ATOM   4979  O OE1 . GLN A 1 683 ? 138.418 114.643 121.412 1.00 54.22  ?  672 GLN A OE1 1 
ATOM   4980  N NE2 . GLN A 1 683 ? 136.404 114.999 122.331 1.00 54.22  ?  672 GLN A NE2 1 
ATOM   4981  N N   . GLU A 1 684 ? 132.324 116.517 119.104 1.00 51.30  ?  673 GLU A N   1 
ATOM   4982  C CA  . GLU A 1 684 ? 130.936 116.128 118.904 1.00 51.30  ?  673 GLU A CA  1 
ATOM   4983  C C   . GLU A 1 684 ? 130.415 116.488 117.519 1.00 51.30  ?  673 GLU A C   1 
ATOM   4984  O O   . GLU A 1 684 ? 129.692 115.708 116.914 1.00 51.30  ?  673 GLU A O   1 
ATOM   4985  C CB  . GLU A 1 684 ? 130.059 116.758 119.978 1.00 51.30  ?  673 GLU A CB  1 
ATOM   4986  C CG  . GLU A 1 684 ? 130.464 116.356 121.381 1.00 51.30  ?  673 GLU A CG  1 
ATOM   4987  C CD  . GLU A 1 684 ? 129.927 117.297 122.434 1.00 51.30  ?  673 GLU A CD  1 
ATOM   4988  O OE1 . GLU A 1 684 ? 129.056 118.127 122.102 1.00 51.30  ?  673 GLU A OE1 1 
ATOM   4989  O OE2 . GLU A 1 684 ? 130.380 117.209 123.594 1.00 51.30  -1 673 GLU A OE2 1 
ATOM   4990  N N   . PHE A 1 685 ? 130.769 117.662 117.019 1.00 56.25  ?  674 PHE A N   1 
ATOM   4991  C CA  . PHE A 1 685 ? 130.347 118.054 115.685 1.00 56.25  ?  674 PHE A CA  1 
ATOM   4992  C C   . PHE A 1 685 ? 131.001 117.160 114.655 1.00 56.25  ?  674 PHE A C   1 
ATOM   4993  O O   . PHE A 1 685 ? 130.366 116.739 113.696 1.00 56.25  ?  674 PHE A O   1 
ATOM   4994  C CB  . PHE A 1 685 ? 130.677 119.519 115.414 1.00 56.25  ?  674 PHE A CB  1 
ATOM   4995  C CG  . PHE A 1 685 ? 129.669 120.482 115.963 1.00 56.25  ?  674 PHE A CG  1 
ATOM   4996  C CD1 . PHE A 1 685 ? 128.421 120.604 115.379 1.00 56.25  ?  674 PHE A CD1 1 
ATOM   4997  C CD2 . PHE A 1 685 ? 129.976 121.279 117.051 1.00 56.25  ?  674 PHE A CD2 1 
ATOM   4998  C CE1 . PHE A 1 685 ? 127.491 121.495 115.879 1.00 56.25  ?  674 PHE A CE1 1 
ATOM   4999  C CE2 . PHE A 1 685 ? 129.052 122.172 117.555 1.00 56.25  ?  674 PHE A CE2 1 
ATOM   5000  C CZ  . PHE A 1 685 ? 127.808 122.281 116.967 1.00 56.25  ?  674 PHE A CZ  1 
ATOM   5001  N N   . ILE A 1 686 ? 132.267 116.843 114.868 1.00 59.21  ?  675 ILE A N   1 
ATOM   5002  C CA  . ILE A 1 686 ? 132.990 115.999 113.925 1.00 59.21  ?  675 ILE A CA  1 
ATOM   5003  C C   . ILE A 1 686 ? 132.445 114.575 113.896 1.00 59.21  ?  675 ILE A C   1 
ATOM   5004  O O   . ILE A 1 686 ? 132.373 113.964 112.835 1.00 59.21  ?  675 ILE A O   1 
ATOM   5005  C CB  . ILE A 1 686 ? 134.502 116.002 114.215 1.00 59.21  ?  675 ILE A CB  1 
ATOM   5006  C CG1 . ILE A 1 686 ? 135.052 117.416 114.038 1.00 59.21  ?  675 ILE A CG1 1 
ATOM   5007  C CG2 . ILE A 1 686 ? 135.222 115.030 113.301 1.00 59.21  ?  675 ILE A CG2 1 
ATOM   5008  C CD1 . ILE A 1 686 ? 136.421 117.631 114.634 1.00 59.21  ?  675 ILE A CD1 1 
ATOM   5009  N N   . ARG A 1 687 ? 132.034 114.053 115.044 1.00 61.33  ?  676 ARG A N   1 
ATOM   5010  C CA  . ARG A 1 687 ? 131.463 112.708 115.093 1.00 61.33  ?  676 ARG A CA  1 
ATOM   5011  C C   . ARG A 1 687 ? 130.080 112.625 114.457 1.00 61.33  ?  676 ARG A C   1 
ATOM   5012  O O   . ARG A 1 687 ? 129.597 111.534 114.182 1.00 61.33  ?  676 ARG A O   1 
ATOM   5013  C CB  . ARG A 1 687 ? 131.433 112.195 116.530 1.00 61.33  ?  676 ARG A CB  1 
ATOM   5014  C CG  . ARG A 1 687 ? 132.811 111.934 117.097 1.00 61.33  ?  676 ARG A CG  1 
ATOM   5015  C CD  . ARG A 1 687 ? 132.760 111.632 118.579 1.00 61.33  ?  676 ARG A CD  1 
ATOM   5016  N NE  . ARG A 1 687 ? 134.102 111.624 119.144 1.00 61.33  ?  676 ARG A NE  1 
ATOM   5017  C CZ  . ARG A 1 687 ? 134.374 111.409 120.424 1.00 61.33  ?  676 ARG A CZ  1 
ATOM   5018  N NH1 . ARG A 1 687 ? 135.630 111.424 120.843 1.00 61.33  1  676 ARG A NH1 1 
ATOM   5019  N NH2 . ARG A 1 687 ? 133.391 111.180 121.283 1.00 61.33  ?  676 ARG A NH2 1 
ATOM   5020  N N   . ILE A 1 688 ? 129.445 113.760 114.210 1.00 63.26  ?  677 ILE A N   1 
ATOM   5021  C CA  . ILE A 1 688 ? 128.159 113.754 113.523 1.00 63.26  ?  677 ILE A CA  1 
ATOM   5022  C C   . ILE A 1 688 ? 128.371 114.217 112.093 1.00 63.26  ?  677 ILE A C   1 
ATOM   5023  O O   . ILE A 1 688 ? 127.438 114.683 111.448 1.00 63.26  ?  677 ILE A O   1 
ATOM   5024  C CB  . ILE A 1 688 ? 127.102 114.610 114.249 1.00 63.26  ?  677 ILE A CB  1 
ATOM   5025  C CG1 . ILE A 1 688 ? 127.506 116.084 114.254 1.00 63.26  ?  677 ILE A CG1 1 
ATOM   5026  C CG2 . ILE A 1 688 ? 126.890 114.101 115.665 1.00 63.26  ?  677 ILE A CG2 1 
ATOM   5027  C CD1 . ILE A 1 688 ? 126.430 117.011 114.771 1.00 63.26  ?  677 ILE A CD1 1 
ATOM   5028  N N   . LYS A 1 689 ? 129.701 114.093 111.674 1.00 62.53  ?  678 LYS A N   1 
ATOM   5029  C CA  . LYS A 1 689 ? 130.078 114.440 110.299 1.00 62.53  ?  678 LYS A CA  1 
ATOM   5030  C C   . LYS A 1 689 ? 129.782 115.881 109.915 1.00 62.53  ?  678 LYS A C   1 
ATOM   5031  O O   . LYS A 1 689 ? 129.254 116.139 108.840 1.00 62.53  ?  678 LYS A O   1 
ATOM   5032  C CB  . LYS A 1 689 ? 129.402 113.482 109.312 1.00 30.00  ?  678 LYS A CB  1 
ATOM   5033  C CG  . LYS A 1 689 ? 129.637 112.018 109.631 1.00 30.00  ?  678 LYS A CG  1 
ATOM   5034  C CD  . LYS A 1 689 ? 131.120 111.718 109.735 1.00 30.00  ?  678 LYS A CD  1 
ATOM   5035  C CE  . LYS A 1 689 ? 131.359 110.318 110.269 1.00 30.00  ?  678 LYS A CE  1 
ATOM   5036  N NZ  . LYS A 1 689 ? 130.775 110.153 111.628 1.00 30.00  1  678 LYS A NZ  1 
ATOM   5037  N N   . VAL A 1 690 ? 130.014 116.805 110.759 1.00 53.88  ?  679 VAL A N   1 
ATOM   5038  C CA  . VAL A 1 690 ? 129.934 118.223 110.464 1.00 53.88  ?  679 VAL A CA  1 
ATOM   5039  C C   . VAL A 1 690 ? 131.355 118.742 110.486 1.00 53.88  ?  679 VAL A C   1 
ATOM   5040  O O   . VAL A 1 690 ? 132.066 118.556 111.467 1.00 53.88  ?  679 VAL A O   1 
ATOM   5041  C CB  . VAL A 1 690 ? 129.079 118.988 111.483 1.00 53.88  ?  679 VAL A CB  1 
ATOM   5042  C CG1 . VAL A 1 690 ? 129.233 120.488 111.294 1.00 53.88  ?  679 VAL A CG1 1 
ATOM   5043  C CG2 . VAL A 1 690 ? 127.623 118.570 111.381 1.00 53.88  ?  679 VAL A CG2 1 
ATOM   5044  N N   . ASP A 1 691 ? 131.787 119.365 109.398 1.00 51.06  ?  680 ASP A N   1 
ATOM   5045  C CA  . ASP A 1 691 ? 133.131 119.933 109.350 1.00 51.06  ?  680 ASP A CA  1 
ATOM   5046  C C   . ASP A 1 691 ? 133.218 121.191 110.182 1.00 51.06  ?  680 ASP A C   1 
ATOM   5047  O O   . ASP A 1 691 ? 132.293 121.991 110.209 1.00 51.06  ?  680 ASP A O   1 
ATOM   5048  C CB  . ASP A 1 691 ? 133.560 120.208 107.913 1.00 51.06  ?  680 ASP A CB  1 
ATOM   5049  C CG  . ASP A 1 691 ? 133.769 118.940 107.118 1.00 51.06  ?  680 ASP A CG  1 
ATOM   5050  O OD1 . ASP A 1 691 ? 133.763 119.009 105.873 1.00 51.06  ?  680 ASP A OD1 1 
ATOM   5051  O OD2 . ASP A 1 691 ? 133.932 117.872 107.738 1.00 51.06  -1 680 ASP A OD2 1 
ATOM   5052  N N   . VAL A 1 692 ? 134.329 121.354 110.876 1.00 47.73  ?  681 VAL A N   1 
ATOM   5053  C CA  . VAL A 1 692 ? 134.489 122.505 111.742 1.00 47.73  ?  681 VAL A CA  1 
ATOM   5054  C C   . VAL A 1 692 ? 135.702 123.323 111.334 1.00 47.73  ?  681 VAL A C   1 
ATOM   5055  O O   . VAL A 1 692 ? 136.735 122.773 110.984 1.00 47.73  ?  681 VAL A O   1 
ATOM   5056  C CB  . VAL A 1 692 ? 134.601 122.073 113.217 1.00 47.73  ?  681 VAL A CB  1 
ATOM   5057  C CG1 . VAL A 1 692 ? 134.663 123.294 114.121 1.00 47.73  ?  681 VAL A CG1 1 
ATOM   5058  C CG2 . VAL A 1 692 ? 133.424 121.193 113.603 1.00 47.73  ?  681 VAL A CG2 1 
ATOM   5059  N N   . TYR A 1 693 ? 135.567 124.640 111.366 1.00 44.71  ?  682 TYR A N   1 
ATOM   5060  C CA  . TYR A 1 693 ? 136.648 125.510 110.944 1.00 44.71  ?  682 TYR A CA  1 
ATOM   5061  C C   . TYR A 1 693 ? 136.847 126.658 111.898 1.00 44.71  ?  682 TYR A C   1 
ATOM   5062  O O   . TYR A 1 693 ? 135.889 127.300 112.304 1.00 44.71  ?  682 TYR A O   1 
ATOM   5063  C CB  . TYR A 1 693 ? 136.341 126.067 109.559 1.00 44.71  ?  682 TYR A CB  1 
ATOM   5064  C CG  . TYR A 1 693 ? 136.100 125.011 108.512 1.00 44.71  ?  682 TYR A CG  1 
ATOM   5065  C CD1 . TYR A 1 693 ? 137.132 124.563 107.704 1.00 44.71  ?  682 TYR A CD1 1 
ATOM   5066  C CD2 . TYR A 1 693 ? 134.838 124.458 108.333 1.00 44.71  ?  682 TYR A CD2 1 
ATOM   5067  C CE1 . TYR A 1 693 ? 136.916 123.595 106.744 1.00 44.71  ?  682 TYR A CE1 1 
ATOM   5068  C CE2 . TYR A 1 693 ? 134.615 123.489 107.378 1.00 44.71  ?  682 TYR A CE2 1 
ATOM   5069  C CZ  . TYR A 1 693 ? 135.658 123.062 106.587 1.00 44.71  ?  682 TYR A CZ  1 
ATOM   5070  O OH  . TYR A 1 693 ? 135.446 122.100 105.632 1.00 44.71  ?  682 TYR A OH  1 
ATOM   5071  N N   . ILE A 1 694 ? 138.091 126.920 112.263 1.00 43.40  ?  683 ILE A N   1 
ATOM   5072  C CA  . ILE A 1 694 ? 138.386 128.056 113.109 1.00 43.40  ?  683 ILE A CA  1 
ATOM   5073  C C   . ILE A 1 694 ? 139.162 129.024 112.253 1.00 43.40  ?  683 ILE A C   1 
ATOM   5074  O O   . ILE A 1 694 ? 140.163 128.661 111.652 1.00 43.40  ?  683 ILE A O   1 
ATOM   5075  C CB  . ILE A 1 694 ? 139.186 127.660 114.355 1.00 43.40  ?  683 ILE A CB  1 
ATOM   5076  C CG1 . ILE A 1 694 ? 138.444 126.569 115.128 1.00 43.40  ?  683 ILE A CG1 1 
ATOM   5077  C CG2 . ILE A 1 694 ? 139.433 128.876 115.233 1.00 43.40  ?  683 ILE A CG2 1 
ATOM   5078  C CD1 . ILE A 1 694 ? 139.178 126.084 116.355 1.00 43.40  ?  683 ILE A CD1 1 
ATOM   5079  N N   . VAL A 1 695 ? 138.694 130.257 112.176 1.00 45.20  ?  684 VAL A N   1 
ATOM   5080  C CA  . VAL A 1 695 ? 139.326 131.222 111.298 1.00 45.20  ?  684 VAL A CA  1 
ATOM   5081  C C   . VAL A 1 695 ? 139.610 132.534 111.984 1.00 45.20  ?  684 VAL A C   1 
ATOM   5082  O O   . VAL A 1 695 ? 139.168 132.764 113.106 1.00 45.20  ?  684 VAL A O   1 
ATOM   5083  C CB  . VAL A 1 695 ? 138.427 131.517 110.079 1.00 45.20  ?  684 VAL A CB  1 
ATOM   5084  C CG1 . VAL A 1 695 ? 138.149 130.244 109.296 1.00 45.20  ?  684 VAL A CG1 1 
ATOM   5085  C CG2 . VAL A 1 695 ? 137.128 132.171 110.524 1.00 45.20  ?  684 VAL A CG2 1 
ATOM   5086  N N   . GLY A 1 696 ? 140.345 133.401 111.305 1.00 47.76  ?  685 GLY A N   1 
ATOM   5087  C CA  . GLY A 1 696 ? 140.614 134.716 111.840 1.00 47.76  ?  685 GLY A CA  1 
ATOM   5088  C C   . GLY A 1 696 ? 141.651 134.784 112.934 1.00 47.76  ?  685 GLY A C   1 
ATOM   5089  O O   . GLY A 1 696 ? 141.851 135.861 113.504 1.00 47.76  ?  685 GLY A O   1 
ATOM   5090  N N   . THR A 1 697 ? 142.281 133.676 113.294 1.00 53.40  ?  686 THR A N   1 
ATOM   5091  C CA  . THR A 1 697 ? 143.220 133.679 114.419 1.00 53.40  ?  686 THR A CA  1 
ATOM   5092  C C   . THR A 1 697 ? 144.651 134.003 114.009 1.00 53.40  ?  686 THR A C   1 
ATOM   5093  O O   . THR A 1 697 ? 145.016 133.828 112.853 1.00 53.40  ?  686 THR A O   1 
ATOM   5094  C CB  . THR A 1 697 ? 143.229 132.321 115.149 1.00 53.40  ?  686 THR A CB  1 
ATOM   5095  O OG1 . THR A 1 697 ? 143.657 131.294 114.248 1.00 53.40  ?  686 THR A OG1 1 
ATOM   5096  C CG2 . THR A 1 697 ? 141.846 131.985 115.668 1.00 53.40  ?  686 THR A CG2 1 
ATOM   5097  N N   . ASP A 1 698 ? 145.465 134.479 114.949 1.00 57.72  ?  687 ASP A N   1 
ATOM   5098  C CA  . ASP A 1 698 ? 146.879 134.742 114.644 1.00 57.72  ?  687 ASP A CA  1 
ATOM   5099  C C   . ASP A 1 698 ? 147.766 133.536 114.937 1.00 57.72  ?  687 ASP A C   1 
ATOM   5100  O O   . ASP A 1 698 ? 147.312 132.562 115.528 1.00 57.72  ?  687 ASP A O   1 
ATOM   5101  C CB  . ASP A 1 698 ? 147.398 135.989 115.371 1.00 57.72  ?  687 ASP A CB  1 
ATOM   5102  C CG  . ASP A 1 698 ? 147.426 135.829 116.876 1.00 57.72  ?  687 ASP A CG  1 
ATOM   5103  O OD1 . ASP A 1 698 ? 147.921 136.750 117.559 1.00 57.72  ?  687 ASP A OD1 1 
ATOM   5104  O OD2 . ASP A 1 698 ? 146.956 134.793 117.383 1.00 57.72  -1 687 ASP A OD2 1 
ATOM   5105  N N   . ASP A 1 699 ? 149.024 133.595 114.519 1.00 61.05  ?  688 ASP A N   1 
ATOM   5106  C CA  . ASP A 1 699 ? 149.943 132.463 114.691 1.00 61.05  ?  688 ASP A CA  1 
ATOM   5107  C C   . ASP A 1 699 ? 150.244 132.108 116.133 1.00 61.05  ?  688 ASP A C   1 
ATOM   5108  O O   . ASP A 1 699 ? 150.365 130.936 116.475 1.00 61.05  ?  688 ASP A O   1 
ATOM   5109  C CB  . ASP A 1 699 ? 151.257 132.758 113.974 1.00 61.05  ?  688 ASP A CB  1 
ATOM   5110  C CG  . ASP A 1 699 ? 152.325 131.736 114.285 1.00 61.05  ?  688 ASP A CG  1 
ATOM   5111  O OD1 . ASP A 1 699 ? 152.032 130.524 114.204 1.00 61.05  ?  688 ASP A OD1 1 
ATOM   5112  O OD2 . ASP A 1 699 ? 153.463 132.144 114.600 1.00 61.05  -1 688 ASP A OD2 1 
ATOM   5113  N N   . ASP A 1 700 ? 150.384 133.112 116.978 1.00 60.19  ?  689 ASP A N   1 
ATOM   5114  C CA  . ASP A 1 700 ? 150.650 132.867 118.381 1.00 60.19  ?  689 ASP A CA  1 
ATOM   5115  C C   . ASP A 1 700 ? 149.523 132.069 118.999 1.00 60.19  ?  689 ASP A C   1 
ATOM   5116  O O   . ASP A 1 700 ? 149.764 131.187 119.814 1.00 60.19  ?  689 ASP A O   1 
ATOM   5117  C CB  . ASP A 1 700 ? 150.815 134.193 119.114 1.00 60.19  ?  689 ASP A CB  1 
ATOM   5118  C CG  . ASP A 1 700 ? 151.968 135.008 118.582 1.00 60.19  ?  689 ASP A CG  1 
ATOM   5119  O OD1 . ASP A 1 700 ? 151.876 136.251 118.614 1.00 60.19  ?  689 ASP A OD1 1 
ATOM   5120  O OD2 . ASP A 1 700 ? 152.961 134.407 118.120 1.00 60.19  -1 689 ASP A OD2 1 
ATOM   5121  N N   . PHE A 1 701 ? 148.292 132.376 118.610 1.00 54.87  ?  690 PHE A N   1 
ATOM   5122  C CA  . PHE A 1 701 ? 147.142 131.663 119.135 1.00 54.87  ?  690 PHE A CA  1 
ATOM   5123  C C   . PHE A 1 701 ? 147.237 130.183 118.820 1.00 54.87  ?  690 PHE A C   1 
ATOM   5124  O O   . PHE A 1 701 ? 147.005 129.350 119.685 1.00 54.87  ?  690 PHE A O   1 
ATOM   5125  C CB  . PHE A 1 701 ? 145.856 132.251 118.549 1.00 54.87  ?  690 PHE A CB  1 
ATOM   5126  C CG  . PHE A 1 701 ? 144.600 131.591 119.034 1.00 54.87  ?  690 PHE A CG  1 
ATOM   5127  C CD1 . PHE A 1 701 ? 144.126 130.442 118.427 1.00 54.87  ?  690 PHE A CD1 1 
ATOM   5128  C CD2 . PHE A 1 701 ? 143.882 132.134 120.085 1.00 54.87  ?  690 PHE A CD2 1 
ATOM   5129  C CE1 . PHE A 1 701 ? 142.966 129.838 118.869 1.00 54.87  ?  690 PHE A CE1 1 
ATOM   5130  C CE2 . PHE A 1 701 ? 142.720 131.536 120.531 1.00 54.87  ?  690 PHE A CE2 1 
ATOM   5131  C CZ  . PHE A 1 701 ? 142.262 130.386 119.921 1.00 54.87  ?  690 PHE A CZ  1 
ATOM   5132  N N   . ILE A 1 702 ? 147.584 129.855 117.584 1.00 56.28  ?  691 ILE A N   1 
ATOM   5133  C CA  . ILE A 1 702 ? 147.680 128.462 117.184 1.00 56.28  ?  691 ILE A CA  1 
ATOM   5134  C C   . ILE A 1 702 ? 148.859 127.791 117.850 1.00 56.28  ?  691 ILE A C   1 
ATOM   5135  O O   . ILE A 1 702 ? 148.767 126.642 118.270 1.00 56.28  ?  691 ILE A O   1 
ATOM   5136  C CB  . ILE A 1 702 ? 147.801 128.329 115.659 1.00 56.28  ?  691 ILE A CB  1 
ATOM   5137  C CG1 . ILE A 1 702 ? 146.639 129.053 114.980 1.00 56.28  ?  691 ILE A CG1 1 
ATOM   5138  C CG2 . ILE A 1 702 ? 147.836 126.865 115.253 1.00 56.28  ?  691 ILE A CG2 1 
ATOM   5139  C CD1 . ILE A 1 702 ? 146.633 128.934 113.473 1.00 56.28  ?  691 ILE A CD1 1 
ATOM   5140  N N   . GLU A 1 703 ? 149.969 128.495 118.027 1.00 59.18  ?  692 GLU A N   1 
ATOM   5141  C CA  . GLU A 1 703 ? 151.103 127.915 118.742 1.00 59.18  ?  692 GLU A CA  1 
ATOM   5142  C C   . GLU A 1 703 ? 150.731 127.489 120.160 1.00 59.18  ?  692 GLU A C   1 
ATOM   5143  O O   . GLU A 1 703 ? 151.061 126.383 120.584 1.00 59.18  ?  692 GLU A O   1 
ATOM   5144  C CB  . GLU A 1 703 ? 152.273 128.899 118.769 1.00 59.18  ?  692 GLU A CB  1 
ATOM   5145  C CG  . GLU A 1 703 ? 153.406 128.496 119.695 1.00 59.18  ?  692 GLU A CG  1 
ATOM   5146  C CD  . GLU A 1 703 ? 154.083 127.208 119.272 1.00 59.18  ?  692 GLU A CD  1 
ATOM   5147  O OE1 . GLU A 1 703 ? 154.697 126.549 120.138 1.00 59.18  ?  692 GLU A OE1 1 
ATOM   5148  O OE2 . GLU A 1 703 ? 153.998 126.852 118.078 1.00 59.18  -1 692 GLU A OE2 1 
ATOM   5149  N N   . LYS A 1 704 ? 150.039 128.355 120.887 1.00 56.25  ?  693 LYS A N   1 
ATOM   5150  C CA  . LYS A 1 704 ? 149.621 128.037 122.247 1.00 56.25  ?  693 LYS A CA  1 
ATOM   5151  C C   . LYS A 1 704 ? 148.701 126.824 122.312 1.00 56.25  ?  693 LYS A C   1 
ATOM   5152  O O   . LYS A 1 704 ? 148.788 126.030 123.245 1.00 56.25  ?  693 LYS A O   1 
ATOM   5153  C CB  . LYS A 1 704 ? 148.934 129.248 122.878 1.00 56.25  ?  693 LYS A CB  1 
ATOM   5154  C CG  . LYS A 1 704 ? 149.828 130.463 123.017 1.00 56.25  ?  693 LYS A CG  1 
ATOM   5155  C CD  . LYS A 1 704 ? 149.123 131.577 123.768 1.00 56.25  ?  693 LYS A CD  1 
ATOM   5156  C CE  . LYS A 1 704 ? 149.991 132.820 123.842 1.00 56.25  ?  693 LYS A CE  1 
ATOM   5157  N NZ  . LYS A 1 704 ? 150.304 133.351 122.487 1.00 56.25  1  693 LYS A NZ  1 
ATOM   5158  N N   . LEU A 1 705 ? 147.819 126.679 121.332 1.00 54.22  ?  694 LEU A N   1 
ATOM   5159  C CA  . LEU A 1 705 ? 146.889 125.557 121.309 1.00 54.22  ?  694 LEU A CA  1 
ATOM   5160  C C   . LEU A 1 705 ? 147.621 124.240 121.161 1.00 54.22  ?  694 LEU A C   1 
ATOM   5161  O O   . LEU A 1 705 ? 147.161 123.214 121.646 1.00 54.22  ?  694 LEU A O   1 
ATOM   5162  C CB  . LEU A 1 705 ? 145.867 125.738 120.182 1.00 54.22  ?  694 LEU A CB  1 
ATOM   5163  C CG  . LEU A 1 705 ? 144.536 124.999 120.293 1.00 54.22  ?  694 LEU A CG  1 
ATOM   5164  C CD1 . LEU A 1 705 ? 143.881 125.288 121.632 1.00 54.22  ?  694 LEU A CD1 1 
ATOM   5165  C CD2 . LEU A 1 705 ? 143.620 125.395 119.148 1.00 54.22  ?  694 LEU A CD2 1 
ATOM   5166  N N   . ASN A 1 706 ? 148.756 124.254 120.479 1.00 57.78  ?  695 ASN A N   1 
ATOM   5167  C CA  . ASN A 1 706 ? 149.560 123.048 120.356 1.00 57.78  ?  695 ASN A CA  1 
ATOM   5168  C C   . ASN A 1 706 ? 150.107 122.623 121.714 1.00 57.78  ?  695 ASN A C   1 
ATOM   5169  O O   . ASN A 1 706 ? 150.239 121.435 121.986 1.00 57.78  ?  695 ASN A O   1 
ATOM   5170  C CB  . ASN A 1 706 ? 150.696 123.277 119.365 1.00 57.78  ?  695 ASN A CB  1 
ATOM   5171  C CG  . ASN A 1 706 ? 150.204 123.478 117.949 1.00 57.78  ?  695 ASN A CG  1 
ATOM   5172  O OD1 . ASN A 1 706 ? 149.675 122.559 117.330 1.00 57.78  ?  695 ASN A OD1 1 
ATOM   5173  N ND2 . ASN A 1 706 ? 150.387 124.682 117.425 1.00 57.78  ?  695 ASN A ND2 1 
ATOM   5174  N N   . ARG A 1 707 ? 150.433 123.589 122.566 1.00 57.27  ?  696 ARG A N   1 
ATOM   5175  C CA  . ARG A 1 707 ? 150.914 123.271 123.910 1.00 57.27  ?  696 ARG A CA  1 
ATOM   5176  C C   . ARG A 1 707 ? 149.816 122.698 124.802 1.00 57.27  ?  696 ARG A C   1 
ATOM   5177  O O   . ARG A 1 707 ? 150.117 122.020 125.780 1.00 57.27  ?  696 ARG A O   1 
ATOM   5178  C CB  . ARG A 1 707 ? 151.523 124.507 124.568 1.00 57.27  ?  696 ARG A CB  1 
ATOM   5179  C CG  . ARG A 1 707 ? 152.324 125.380 123.622 1.00 57.27  ?  696 ARG A CG  1 
ATOM   5180  C CD  . ARG A 1 707 ? 152.544 126.756 124.225 1.00 57.27  ?  696 ARG A CD  1 
ATOM   5181  N NE  . ARG A 1 707 ? 152.861 127.756 123.212 1.00 57.27  ?  696 ARG A NE  1 
ATOM   5182  C CZ  . ARG A 1 707 ? 152.993 129.053 123.466 1.00 57.27  ?  696 ARG A CZ  1 
ATOM   5183  N NH1 . ARG A 1 707 ? 153.280 129.898 122.487 1.00 57.27  1  696 ARG A NH1 1 
ATOM   5184  N NH2 . ARG A 1 707 ? 152.833 129.504 124.702 1.00 57.27  ?  696 ARG A NH2 1 
ATOM   5185  N N   . TYR A 1 708 ? 148.556 122.965 124.477 1.00 52.41  ?  697 TYR A N   1 
ATOM   5186  C CA  . TYR A 1 708 ? 147.438 122.427 125.254 1.00 52.41  ?  697 TYR A CA  1 
ATOM   5187  C C   . TYR A 1 708 ? 147.105 121.007 124.861 1.00 52.41  ?  697 TYR A C   1 
ATOM   5188  O O   . TYR A 1 708 ? 146.182 120.420 125.411 1.00 52.41  ?  697 TYR A O   1 
ATOM   5189  C CB  . TYR A 1 708 ? 146.179 123.268 125.064 1.00 52.41  ?  697 TYR A CB  1 
ATOM   5190  C CG  . TYR A 1 708 ? 146.126 124.571 125.816 1.00 52.41  ?  697 TYR A CG  1 
ATOM   5191  C CD1 . TYR A 1 708 ? 146.404 125.768 125.179 1.00 52.41  ?  697 TYR A CD1 1 
ATOM   5192  C CD2 . TYR A 1 708 ? 145.758 124.608 127.153 1.00 52.41  ?  697 TYR A CD2 1 
ATOM   5193  C CE1 . TYR A 1 708 ? 146.339 126.967 125.856 1.00 52.41  ?  697 TYR A CE1 1 
ATOM   5194  C CE2 . TYR A 1 708 ? 145.689 125.804 127.838 1.00 52.41  ?  697 TYR A CE2 1 
ATOM   5195  C CZ  . TYR A 1 708 ? 145.981 126.980 127.183 1.00 52.41  ?  697 TYR A CZ  1 
ATOM   5196  O OH  . TYR A 1 708 ? 145.916 128.176 127.854 1.00 52.41  ?  697 TYR A OH  1 
ATOM   5197  N N   . GLU A 1 709 ? 147.826 120.457 123.894 1.00 56.91  ?  698 GLU A N   1 
ATOM   5198  C CA  . GLU A 1 709 ? 147.537 119.109 123.398 1.00 56.91  ?  698 GLU A CA  1 
ATOM   5199  C C   . GLU A 1 709 ? 146.145 119.050 122.797 1.00 56.91  ?  698 GLU A C   1 
ATOM   5200  O O   . GLU A 1 709 ? 145.448 118.052 122.937 1.00 56.91  ?  698 GLU A O   1 
ATOM   5201  C CB  . GLU A 1 709 ? 147.690 118.079 124.512 1.00 56.91  ?  698 GLU A CB  1 
ATOM   5202  C CG  . GLU A 1 709 ? 149.029 118.162 125.227 1.00 56.91  ?  698 GLU A CG  1 
ATOM   5203  C CD  . GLU A 1 709 ? 149.011 117.476 126.576 1.00 56.91  ?  698 GLU A CD  1 
ATOM   5204  O OE1 . GLU A 1 709 ? 150.056 117.482 127.259 1.00 56.91  ?  698 GLU A OE1 1 
ATOM   5205  O OE2 . GLU A 1 709 ? 147.951 116.936 126.955 1.00 56.91  -1 698 GLU A OE2 1 
ATOM   5206  N N   . PHE A 1 710 ? 145.740 120.121 122.128 1.00 52.83  ?  699 PHE A N   1 
ATOM   5207  C CA  . PHE A 1 710 ? 144.415 120.191 121.529 1.00 52.83  ?  699 PHE A CA  1 
ATOM   5208  C C   . PHE A 1 710 ? 144.261 119.321 120.291 1.00 52.83  ?  699 PHE A C   1 
ATOM   5209  O O   . PHE A 1 710 ? 143.201 118.757 120.061 1.00 52.83  ?  699 PHE A O   1 
ATOM   5210  C CB  . PHE A 1 710 ? 144.134 121.649 121.176 1.00 52.83  ?  699 PHE A CB  1 
ATOM   5211  C CG  . PHE A 1 710 ? 142.777 121.895 120.592 1.00 52.83  ?  699 PHE A CG  1 
ATOM   5212  C CD1 . PHE A 1 710 ? 142.616 122.034 119.227 1.00 52.83  ?  699 PHE A CD1 1 
ATOM   5213  C CD2 . PHE A 1 710 ? 141.668 122.013 121.411 1.00 52.83  ?  699 PHE A CD2 1 
ATOM   5214  C CE1 . PHE A 1 710 ? 141.371 122.274 118.684 1.00 52.83  ?  699 PHE A CE1 1 
ATOM   5215  C CE2 . PHE A 1 710 ? 140.421 122.253 120.875 1.00 52.83  ?  699 PHE A CE2 1 
ATOM   5216  C CZ  . PHE A 1 710 ? 140.271 122.384 119.511 1.00 52.83  ?  699 PHE A CZ  1 
ATOM   5217  N N   . PHE A 1 711 ? 145.300 119.241 119.477 1.00 55.30  ?  700 PHE A N   1 
ATOM   5218  C CA  . PHE A 1 711 ? 145.182 118.510 118.221 1.00 55.30  ?  700 PHE A CA  1 
ATOM   5219  C C   . PHE A 1 711 ? 145.479 117.034 118.364 1.00 55.30  ?  700 PHE A C   1 
ATOM   5220  O O   . PHE A 1 711 ? 146.320 116.638 119.161 1.00 55.30  ?  700 PHE A O   1 
ATOM   5221  C CB  . PHE A 1 711 ? 146.079 119.146 117.151 1.00 55.30  ?  700 PHE A CB  1 
ATOM   5222  C CG  . PHE A 1 711 ? 145.759 120.583 116.878 1.00 55.30  ?  700 PHE A CG  1 
ATOM   5223  C CD1 . PHE A 1 711 ? 144.613 120.927 116.184 1.00 55.30  ?  700 PHE A CD1 1 
ATOM   5224  C CD2 . PHE A 1 711 ? 146.597 121.591 117.321 1.00 55.30  ?  700 PHE A CD2 1 
ATOM   5225  C CE1 . PHE A 1 711 ? 144.310 122.249 115.932 1.00 55.30  ?  700 PHE A CE1 1 
ATOM   5226  C CE2 . PHE A 1 711 ? 146.302 122.915 117.072 1.00 55.30  ?  700 PHE A CE2 1 
ATOM   5227  C CZ  . PHE A 1 711 ? 145.156 123.244 116.377 1.00 55.30  ?  700 PHE A CZ  1 
ATOM   5228  N N   . ASP A 1 712 ? 144.781 116.220 117.588 1.00 60.86  ?  701 ASP A N   1 
ATOM   5229  C CA  . ASP A 1 712 ? 144.964 114.780 117.653 1.00 60.86  ?  701 ASP A CA  1 
ATOM   5230  C C   . ASP A 1 712 ? 144.356 114.205 116.392 1.00 60.86  ?  701 ASP A C   1 
ATOM   5231  O O   . ASP A 1 712 ? 144.138 114.925 115.422 1.00 60.86  ?  701 ASP A O   1 
ATOM   5232  C CB  . ASP A 1 712 ? 144.158 114.181 118.808 1.00 60.86  ?  701 ASP A CB  1 
ATOM   5233  C CG  . ASP A 1 712 ? 142.672 114.456 118.693 1.00 60.86  ?  701 ASP A CG  1 
ATOM   5234  O OD1 . ASP A 1 712 ? 142.268 115.213 117.792 1.00 60.86  ?  701 ASP A OD1 1 
ATOM   5235  O OD2 . ASP A 1 712 ? 141.906 113.910 119.511 1.00 60.86  -1 701 ASP A OD2 1 
ATOM   5236  N N   . GLY A 1 713 ? 144.088 112.905 116.396 1.00 60.90  ?  702 GLY A N   1 
ATOM   5237  C CA  . GLY A 1 713 ? 143.639 112.222 115.198 1.00 60.90  ?  702 GLY A CA  1 
ATOM   5238  C C   . GLY A 1 713 ? 142.324 112.729 114.653 1.00 60.90  ?  702 GLY A C   1 
ATOM   5239  O O   . GLY A 1 713 ? 142.151 112.823 113.441 1.00 60.90  ?  702 GLY A O   1 
ATOM   5240  N N   . GLU A 1 714 ? 141.389 113.049 115.538 1.00 60.15  ?  703 GLU A N   1 
ATOM   5241  C CA  . GLU A 1 714 ? 140.080 113.521 115.104 1.00 60.15  ?  703 GLU A CA  1 
ATOM   5242  C C   . GLU A 1 714 ? 140.074 115.025 114.896 1.00 60.15  ?  703 GLU A C   1 
ATOM   5243  O O   . GLU A 1 714 ? 139.512 115.512 113.922 1.00 60.15  ?  703 GLU A O   1 
ATOM   5244  C CB  . GLU A 1 714 ? 139.007 113.117 116.116 1.00 60.15  ?  703 GLU A CB  1 
ATOM   5245  C CG  . GLU A 1 714 ? 137.634 113.699 115.839 1.00 60.15  ?  703 GLU A CG  1 
ATOM   5246  C CD  . GLU A 1 714 ? 136.607 113.283 116.873 1.00 60.15  ?  703 GLU A CD  1 
ATOM   5247  O OE1 . GLU A 1 714 ? 135.434 113.688 116.743 1.00 60.15  ?  703 GLU A OE1 1 
ATOM   5248  O OE2 . GLU A 1 714 ? 136.972 112.550 117.815 1.00 60.15  -1 703 GLU A OE2 1 
ATOM   5249  N N   . VAL A 1 715 ? 140.695 115.756 115.808 1.00 56.87  ?  704 VAL A N   1 
ATOM   5250  C CA  . VAL A 1 715 ? 140.772 117.202 115.688 1.00 56.87  ?  704 VAL A CA  1 
ATOM   5251  C C   . VAL A 1 715 ? 142.120 117.560 115.121 1.00 56.87  ?  704 VAL A C   1 
ATOM   5252  O O   . VAL A 1 715 ? 143.137 117.370 115.777 1.00 56.87  ?  704 VAL A O   1 
ATOM   5253  C CB  . VAL A 1 715 ? 140.597 117.873 117.047 1.00 56.87  ?  704 VAL A CB  1 
ATOM   5254  C CG1 . VAL A 1 715 ? 140.607 119.384 116.904 1.00 56.87  ?  704 VAL A CG1 1 
ATOM   5255  C CG2 . VAL A 1 715 ? 139.335 117.364 117.717 1.00 56.87  ?  704 VAL A CG2 1 
ATOM   5256  N N   . LYS A 1 716 ? 142.143 118.088 113.909 1.00 55.10  ?  705 LYS A N   1 
ATOM   5257  C CA  . LYS A 1 716 ? 143.413 118.363 113.253 1.00 55.10  ?  705 LYS A CA  1 
ATOM   5258  C C   . LYS A 1 716 ? 143.675 119.839 113.037 1.00 55.10  ?  705 LYS A C   1 
ATOM   5259  O O   . LYS A 1 716 ? 142.776 120.655 113.165 1.00 55.10  ?  705 LYS A O   1 
ATOM   5260  C CB  . LYS A 1 716 ? 143.439 117.641 111.912 1.00 55.10  ?  705 LYS A CB  1 
ATOM   5261  C CG  . LYS A 1 716 ? 143.011 116.187 111.990 1.00 55.10  ?  705 LYS A CG  1 
ATOM   5262  C CD  . LYS A 1 716 ? 142.837 115.610 110.597 1.00 55.10  ?  705 LYS A CD  1 
ATOM   5263  C CE  . LYS A 1 716 ? 142.312 114.187 110.649 1.00 55.10  ?  705 LYS A CE  1 
ATOM   5264  N NZ  . LYS A 1 716 ? 142.121 113.624 109.284 1.00 55.10  1  705 LYS A NZ  1 
ATOM   5265  N N   . SER A 1 717 ? 144.912 120.178 112.706 1.00 54.73  ?  706 SER A N   1 
ATOM   5266  C CA  . SER A 1 717 ? 145.268 121.570 112.457 1.00 54.73  ?  706 SER A CA  1 
ATOM   5267  C C   . SER A 1 717 ? 144.773 122.066 111.102 1.00 54.73  ?  706 SER A C   1 
ATOM   5268  O O   . SER A 1 717 ? 144.969 123.229 110.775 1.00 54.73  ?  706 SER A O   1 
ATOM   5269  C CB  . SER A 1 717 ? 146.783 121.749 112.576 1.00 54.73  ?  706 SER A CB  1 
ATOM   5270  O OG  . SER A 1 717 ? 147.207 121.583 113.915 1.00 54.73  ?  706 SER A OG  1 
ATOM   5271  N N   . SER A 1 718 ? 144.142 121.199 110.320 1.00 52.44  ?  707 SER A N   1 
ATOM   5272  C CA  . SER A 1 718 ? 143.587 121.586 109.021 1.00 52.44  ?  707 SER A CA  1 
ATOM   5273  C C   . SER A 1 718 ? 142.305 122.411 109.161 1.00 52.44  ?  707 SER A C   1 
ATOM   5274  O O   . SER A 1 718 ? 141.916 123.088 108.219 1.00 52.44  ?  707 SER A O   1 
ATOM   5275  C CB  . SER A 1 718 ? 143.360 120.327 108.192 1.00 52.44  ?  707 SER A CB  1 
ATOM   5276  O OG  . SER A 1 718 ? 142.568 119.390 108.896 1.00 52.44  ?  707 SER A OG  1 
ATOM   5277  N N   . ILE A 1 719 ? 141.650 122.360 110.304 1.00 48.33  ?  708 ILE A N   1 
ATOM   5278  C CA  . ILE A 1 719 ? 140.443 123.114 110.623 1.00 48.33  ?  708 ILE A CA  1 
ATOM   5279  C C   . ILE A 1 719 ? 140.707 124.604 110.726 1.00 48.33  ?  708 ILE A C   1 
ATOM   5280  O O   . ILE A 1 719 ? 139.763 125.378 110.908 1.00 48.33  ?  708 ILE A O   1 
ATOM   5281  C CB  . ILE A 1 719 ? 139.807 122.633 111.941 1.00 48.33  ?  708 ILE A CB  1 
ATOM   5282  C CG1 . ILE A 1 719 ? 140.503 123.267 113.139 1.00 48.33  ?  708 ILE A CG1 1 
ATOM   5283  C CG2 . ILE A 1 719 ? 139.845 121.122 112.039 1.00 48.33  ?  708 ILE A CG2 1 
ATOM   5284  C CD1 . ILE A 1 719 ? 139.951 122.823 114.457 1.00 48.33  ?  708 ILE A CD1 1 
ATOM   5285  N N   . PHE A 1 720 ? 141.969 124.995 110.656 1.00 47.80  ?  709 PHE A N   1 
ATOM   5286  C CA  . PHE A 1 720 ? 142.324 126.396 110.783 1.00 47.80  ?  709 PHE A CA  1 
ATOM   5287  C C   . PHE A 1 720 ? 142.507 127.038 109.423 1.00 47.80  ?  709 PHE A C   1 
ATOM   5288  O O   . PHE A 1 720 ? 143.278 126.558 108.602 1.00 47.80  ?  709 PHE A O   1 
ATOM   5289  C CB  . PHE A 1 720 ? 143.572 126.551 111.648 1.00 47.80  ?  709 PHE A CB  1 
ATOM   5290  C CG  . PHE A 1 720 ? 143.287 126.563 113.118 1.00 47.80  ?  709 PHE A CG  1 
ATOM   5291  C CD1 . PHE A 1 720 ? 143.054 127.755 113.777 1.00 47.80  ?  709 PHE A CD1 1 
ATOM   5292  C CD2 . PHE A 1 720 ? 143.240 125.384 113.839 1.00 47.80  ?  709 PHE A CD2 1 
ATOM   5293  C CE1 . PHE A 1 720 ? 142.788 127.775 115.131 1.00 47.80  ?  709 PHE A CE1 1 
ATOM   5294  C CE2 . PHE A 1 720 ? 142.973 125.396 115.192 1.00 47.80  ?  709 PHE A CE2 1 
ATOM   5295  C CZ  . PHE A 1 720 ? 142.746 126.594 115.840 1.00 47.80  ?  709 PHE A CZ  1 
ATOM   5296  N N   . PHE A 1 721 ? 141.773 128.112 109.177 1.00 47.19  ?  710 PHE A N   1 
ATOM   5297  C CA  . PHE A 1 721 ? 141.860 128.811 107.902 1.00 47.19  ?  710 PHE A CA  1 
ATOM   5298  C C   . PHE A 1 721 ? 142.133 130.270 108.174 1.00 47.19  ?  710 PHE A C   1 
ATOM   5299  O O   . PHE A 1 721 ? 141.842 130.766 109.253 1.00 47.19  ?  710 PHE A O   1 
ATOM   5300  C CB  . PHE A 1 721 ? 140.585 128.632 107.076 1.00 47.19  ?  710 PHE A CB  1 
ATOM   5301  C CG  . PHE A 1 721 ? 140.575 127.385 106.248 1.00 47.19  ?  710 PHE A CG  1 
ATOM   5302  C CD1 . PHE A 1 721 ? 140.746 127.453 104.879 1.00 47.19  ?  710 PHE A CD1 1 
ATOM   5303  C CD2 . PHE A 1 721 ? 140.408 126.145 106.839 1.00 47.19  ?  710 PHE A CD2 1 
ATOM   5304  C CE1 . PHE A 1 721 ? 140.746 126.308 104.111 1.00 47.19  ?  710 PHE A CE1 1 
ATOM   5305  C CE2 . PHE A 1 721 ? 140.408 124.995 106.077 1.00 47.19  ?  710 PHE A CE2 1 
ATOM   5306  C CZ  . PHE A 1 721 ? 140.578 125.077 104.711 1.00 47.19  ?  710 PHE A CZ  1 
ATOM   5307  N N   . LEU A 1 722 ? 142.722 130.958 107.209 1.00 47.19  ?  711 LEU A N   1 
ATOM   5308  C CA  . LEU A 1 722 ? 143.083 132.355 107.420 1.00 47.19  ?  711 LEU A CA  1 
ATOM   5309  C C   . LEU A 1 722 ? 141.886 133.241 107.701 1.00 47.19  ?  711 LEU A C   1 
ATOM   5310  O O   . LEU A 1 722 ? 141.905 134.013 108.652 1.00 47.19  ?  711 LEU A O   1 
ATOM   5311  C CB  . LEU A 1 722 ? 143.859 132.898 106.213 1.00 47.19  ?  711 LEU A CB  1 
ATOM   5312  C CG  . LEU A 1 722 ? 145.216 132.271 105.893 1.00 47.19  ?  711 LEU A CG  1 
ATOM   5313  C CD1 . LEU A 1 722 ? 145.904 133.070 104.797 1.00 47.19  ?  711 LEU A CD1 1 
ATOM   5314  C CD2 . LEU A 1 722 ? 146.086 132.221 107.137 1.00 47.19  ?  711 LEU A CD2 1 
ATOM   5315  N N   . THR A 1 723 ? 140.844 133.136 106.888 1.00 46.64  ?  712 THR A N   1 
ATOM   5316  C CA  . THR A 1 723 ? 139.686 134.002 107.043 1.00 46.64  ?  712 THR A CA  1 
ATOM   5317  C C   . THR A 1 723 ? 138.405 133.231 106.832 1.00 46.64  ?  712 THR A C   1 
ATOM   5318  O O   . THR A 1 723 ? 138.447 132.055 106.498 1.00 46.64  ?  712 THR A O   1 
ATOM   5319  C CB  . THR A 1 723 ? 139.723 135.181 106.041 1.00 46.64  ?  712 THR A CB  1 
ATOM   5320  O OG1 . THR A 1 723 ? 139.205 134.759 104.774 1.00 46.64  ?  712 THR A OG1 1 
ATOM   5321  C CG2 . THR A 1 723 ? 141.139 135.712 105.868 1.00 46.64  ?  712 THR A CG2 1 
ATOM   5322  N N   . ILE A 1 724 ? 137.266 133.878 107.043 1.00 43.98  ?  713 ILE A N   1 
ATOM   5323  C CA  . ILE A 1 724 ? 135.974 133.236 106.825 1.00 43.98  ?  713 ILE A CA  1 
ATOM   5324  C C   . ILE A 1 724 ? 135.767 132.888 105.359 1.00 43.98  ?  713 ILE A C   1 
ATOM   5325  O O   . ILE A 1 724 ? 135.319 131.796 105.041 1.00 43.98  ?  713 ILE A O   1 
ATOM   5326  C CB  . ILE A 1 724 ? 134.808 134.130 107.314 1.00 43.98  ?  713 ILE A CB  1 
ATOM   5327  C CG1 . ILE A 1 724 ? 134.903 134.346 108.824 1.00 43.98  ?  713 ILE A CG1 1 
ATOM   5328  C CG2 . ILE A 1 724 ? 133.463 133.526 106.939 1.00 43.98  ?  713 ILE A CG2 1 
ATOM   5329  C CD1 . ILE A 1 724 ? 133.925 135.365 109.361 1.00 43.98  ?  713 ILE A CD1 1 
ATOM   5330  N N   . HIS A 1 725 ? 136.089 133.810 104.469 1.00 45.96  ?  714 HIS A N   1 
ATOM   5331  C CA  . HIS A 1 725 ? 135.898 133.572 103.051 1.00 45.96  ?  714 HIS A CA  1 
ATOM   5332  C C   . HIS A 1 725 ? 136.744 132.399 102.587 1.00 45.96  ?  714 HIS A C   1 
ATOM   5333  O O   . HIS A 1 725 ? 136.296 131.605 101.776 1.00 45.96  ?  714 HIS A O   1 
ATOM   5334  C CB  . HIS A 1 725 ? 136.209 134.837 102.257 1.00 45.96  ?  714 HIS A CB  1 
ATOM   5335  C CG  . HIS A 1 725 ? 135.589 134.866 100.896 1.00 45.96  ?  714 HIS A CG  1 
ATOM   5336  N ND1 . HIS A 1 725 ? 136.335 134.918 99.740  1.00 45.96  ?  714 HIS A ND1 1 
ATOM   5337  C CD2 . HIS A 1 725 ? 134.293 134.845 100.509 1.00 45.96  ?  714 HIS A CD2 1 
ATOM   5338  C CE1 . HIS A 1 725 ? 135.525 134.932 98.698  1.00 45.96  ?  714 HIS A CE1 1 
ATOM   5339  N NE2 . HIS A 1 725 ? 134.280 134.888 99.137  1.00 45.96  ?  714 HIS A NE2 1 
ATOM   5340  N N   . ASP A 1 726 ? 137.951 132.273 103.121 1.00 49.00  ?  715 ASP A N   1 
ATOM   5341  C CA  . ASP A 1 726 ? 138.799 131.139 102.786 1.00 49.00  ?  715 ASP A CA  1 
ATOM   5342  C C   . ASP A 1 726 ? 138.107 129.832 103.142 1.00 49.00  ?  715 ASP A C   1 
ATOM   5343  O O   . ASP A 1 726 ? 138.056 128.918 102.331 1.00 49.00  ?  715 ASP A O   1 
ATOM   5344  C CB  . ASP A 1 726 ? 140.139 131.234 103.517 1.00 49.00  ?  715 ASP A CB  1 
ATOM   5345  C CG  . ASP A 1 726 ? 141.060 132.276 102.926 1.00 49.00  ?  715 ASP A CG  1 
ATOM   5346  O OD1 . ASP A 1 726 ? 141.248 133.330 103.563 1.00 49.00  ?  715 ASP A OD1 1 
ATOM   5347  O OD2 . ASP A 1 726 ? 141.603 132.037 101.829 1.00 49.00  -1 715 ASP A OD2 1 
ATOM   5348  N N   . ALA A 1 727 ? 137.559 129.750 104.349 1.00 47.03  ?  716 ALA A N   1 
ATOM   5349  C CA  . ALA A 1 727 ? 136.863 128.544 104.782 1.00 47.03  ?  716 ALA A CA  1 
ATOM   5350  C C   . ALA A 1 727 ? 135.616 128.296 103.955 1.00 47.03  ?  716 ALA A C   1 
ATOM   5351  O O   . ALA A 1 727 ? 135.368 127.177 103.544 1.00 47.03  ?  716 ALA A O   1 
ATOM   5352  C CB  . ALA A 1 727 ? 136.510 128.631 106.254 1.00 47.03  ?  716 ALA A CB  1 
ATOM   5353  N N   . VAL A 1 728 ? 134.846 129.340 103.693 1.00 47.69  ?  717 VAL A N   1 
ATOM   5354  C CA  . VAL A 1 728 ? 133.644 129.215 102.883 1.00 47.69  ?  717 VAL A CA  1 
ATOM   5355  C C   . VAL A 1 728 ? 133.954 128.715 101.479 1.00 47.69  ?  717 VAL A C   1 
ATOM   5356  O O   . VAL A 1 728 ? 133.287 127.820 100.983 1.00 47.69  ?  717 VAL A O   1 
ATOM   5357  C CB  . VAL A 1 728 ? 132.888 130.558 102.790 1.00 47.69  ?  717 VAL A CB  1 
ATOM   5358  C CG1 . VAL A 1 728 ? 131.777 130.482 101.758 1.00 47.69  ?  717 VAL A CG1 1 
ATOM   5359  C CG2 . VAL A 1 728 ? 132.345 130.969 104.148 1.00 47.69  ?  717 VAL A CG2 1 
ATOM   5360  N N   . LEU A 1 729 ? 134.966 129.282 100.845 1.00 50.68  ?  718 LEU A N   1 
ATOM   5361  C CA  . LEU A 1 729 ? 135.348 128.867 99.505  1.00 50.68  ?  718 LEU A CA  1 
ATOM   5362  C C   . LEU A 1 729 ? 135.830 127.437 99.522  1.00 50.68  ?  718 LEU A C   1 
ATOM   5363  O O   . LEU A 1 729 ? 135.530 126.670 98.619  1.00 50.68  ?  718 LEU A O   1 
ATOM   5364  C CB  . LEU A 1 729 ? 136.439 129.781 98.957  1.00 50.68  ?  718 LEU A CB  1 
ATOM   5365  C CG  . LEU A 1 729 ? 136.057 131.235 98.687  1.00 50.68  ?  718 LEU A CG  1 
ATOM   5366  C CD1 . LEU A 1 729 ? 137.270 132.028 98.229  1.00 50.68  ?  718 LEU A CD1 1 
ATOM   5367  C CD2 . LEU A 1 729 ? 134.941 131.303 97.657  1.00 50.68  ?  718 LEU A CD2 1 
ATOM   5368  N N   . HIS A 1 730 ? 136.575 127.078 100.553 1.00 51.89  ?  719 HIS A N   1 
ATOM   5369  C CA  . HIS A 1 730 ? 137.052 125.715 100.692 1.00 51.89  ?  719 HIS A CA  1 
ATOM   5370  C C   . HIS A 1 730 ? 135.879 124.766 100.799 1.00 51.89  ?  719 HIS A C   1 
ATOM   5371  O O   . HIS A 1 730 ? 135.909 123.676 100.238 1.00 51.89  ?  719 HIS A O   1 
ATOM   5372  C CB  . HIS A 1 730 ? 137.949 125.599 101.919 1.00 51.89  ?  719 HIS A CB  1 
ATOM   5373  C CG  . HIS A 1 730 ? 138.326 124.194 102.260 1.00 51.89  ?  719 HIS A CG  1 
ATOM   5374  N ND1 . HIS A 1 730 ? 139.442 123.576 101.741 1.00 51.89  ?  719 HIS A ND1 1 
ATOM   5375  C CD2 . HIS A 1 730 ? 137.734 123.284 103.069 1.00 51.89  ?  719 HIS A CD2 1 
ATOM   5376  C CE1 . HIS A 1 730 ? 139.522 122.346 102.215 1.00 51.89  ?  719 HIS A CE1 1 
ATOM   5377  N NE2 . HIS A 1 730 ? 138.497 122.145 103.023 1.00 51.89  ?  719 HIS A NE2 1 
ATOM   5378  N N   . ILE A 1 731 ? 134.839 125.176 101.509 1.00 52.69  ?  720 ILE A N   1 
ATOM   5379  C CA  . ILE A 1 731 ? 133.642 124.363 101.633 1.00 52.69  ?  720 ILE A CA  1 
ATOM   5380  C C   . ILE A 1 731 ? 132.856 124.284 100.317 1.00 52.69  ?  720 ILE A C   1 
ATOM   5381  O O   . ILE A 1 731 ? 132.455 123.198 99.922  1.00 52.69  ?  720 ILE A O   1 
ATOM   5382  C CB  . ILE A 1 731 ? 132.734 124.885 102.766 1.00 52.69  ?  720 ILE A CB  1 
ATOM   5383  C CG1 . ILE A 1 731 ? 133.455 124.792 104.111 1.00 52.69  ?  720 ILE A CG1 1 
ATOM   5384  C CG2 . ILE A 1 731 ? 131.419 124.121 102.800 1.00 52.69  ?  720 ILE A CG2 1 
ATOM   5385  C CD1 . ILE A 1 731 ? 132.879 125.704 105.169 1.00 52.69  ?  720 ILE A CD1 1 
ATOM   5386  N N   . LEU A 1 732 ? 132.643 125.411 99.634  1.00 59.12  ?  721 LEU A N   1 
ATOM   5387  C CA  . LEU A 1 732 ? 131.931 125.364 98.362  1.00 59.12  ?  721 LEU A CA  1 
ATOM   5388  C C   . LEU A 1 732 ? 132.609 124.418 97.382  1.00 59.12  ?  721 LEU A C   1 
ATOM   5389  O O   . LEU A 1 732 ? 131.934 123.661 96.679  1.00 59.12  ?  721 LEU A O   1 
ATOM   5390  C CB  . LEU A 1 732 ? 131.818 126.765 97.762  1.00 59.12  ?  721 LEU A CB  1 
ATOM   5391  C CG  . LEU A 1 732 ? 130.889 127.750 98.467  1.00 59.12  ?  721 LEU A CG  1 
ATOM   5392  C CD1 . LEU A 1 732 ? 130.550 128.908 97.551  1.00 59.12  ?  721 LEU A CD1 1 
ATOM   5393  C CD2 . LEU A 1 732 ? 129.628 127.059 98.943  1.00 59.12  ?  721 LEU A CD2 1 
ATOM   5394  N N   . MET A 1 733 ? 133.941 124.444 97.317  1.00 64.41  ?  722 MET A N   1 
ATOM   5395  C CA  . MET A 1 733 ? 134.648 123.547 96.409  1.00 64.41  ?  722 MET A CA  1 
ATOM   5396  C C   . MET A 1 733 ? 134.522 122.092 96.849  1.00 64.41  ?  722 MET A C   1 
ATOM   5397  O O   . MET A 1 733 ? 134.316 121.203 96.018  1.00 64.41  ?  722 MET A O   1 
ATOM   5398  C CB  . MET A 1 733 ? 136.110 123.968 96.283  1.00 64.41  ?  722 MET A CB  1 
ATOM   5399  C CG  . MET A 1 733 ? 136.365 124.950 95.141  1.00 64.41  ?  722 MET A CG  1 
ATOM   5400  S SD  . MET A 1 733 ? 136.366 126.682 95.631  1.00 64.41  ?  722 MET A SD  1 
ATOM   5401  C CE  . MET A 1 733 ? 138.022 126.830 96.269  1.00 64.41  ?  722 MET A CE  1 
ATOM   5402  N N   . LYS A 1 734 ? 134.630 121.830 98.156  1.00 65.58  ?  723 LYS A N   1 
ATOM   5403  C CA  . LYS A 1 734 ? 134.398 120.476 98.658  1.00 65.58  ?  723 LYS A CA  1 
ATOM   5404  C C   . LYS A 1 734 ? 133.020 119.969 98.256  1.00 65.58  ?  723 LYS A C   1 
ATOM   5405  O O   . LYS A 1 734 ? 132.880 118.857 97.735  1.00 65.58  ?  723 LYS A O   1 
ATOM   5406  C CB  . LYS A 1 734 ? 134.543 120.443 100.179 1.00 65.58  ?  723 LYS A CB  1 
ATOM   5407  C CG  . LYS A 1 734 ? 135.935 120.150 100.674 1.00 65.58  ?  723 LYS A CG  1 
ATOM   5408  C CD  . LYS A 1 734 ? 135.905 119.766 102.139 1.00 65.58  ?  723 LYS A CD  1 
ATOM   5409  C CE  . LYS A 1 734 ? 135.194 118.441 102.341 1.00 65.58  ?  723 LYS A CE  1 
ATOM   5410  N NZ  . LYS A 1 734 ? 135.498 117.839 103.667 1.00 65.58  1  723 LYS A NZ  1 
ATOM   5411  N N   . LYS A 1 735 ? 131.988 120.780 98.486  1.00 69.51  ?  724 LYS A N   1 
ATOM   5412  C CA  . LYS A 1 735 ? 130.622 120.317 98.268  1.00 69.51  ?  724 LYS A CA  1 
ATOM   5413  C C   . LYS A 1 735 ? 130.315 120.176 96.783  1.00 69.51  ?  724 LYS A C   1 
ATOM   5414  O O   . LYS A 1 735 ? 129.637 119.229 96.370  1.00 69.51  ?  724 LYS A O   1 
ATOM   5415  C CB  . LYS A 1 735 ? 129.637 121.263 98.946  1.00 69.51  ?  724 LYS A CB  1 
ATOM   5416  C CG  . LYS A 1 735 ? 129.710 121.208 100.461 1.00 69.51  ?  724 LYS A CG  1 
ATOM   5417  C CD  . LYS A 1 735 ? 129.850 119.775 100.955 1.00 69.51  ?  724 LYS A CD  1 
ATOM   5418  C CE  . LYS A 1 735 ? 130.599 119.711 102.275 1.00 69.51  ?  724 LYS A CE  1 
ATOM   5419  N NZ  . LYS A 1 735 ? 130.830 118.308 102.715 1.00 69.51  1  724 LYS A NZ  1 
ATOM   5420  N N   . ASP A 1 736 ? 130.841 121.076 95.969  1.00 78.43  ?  725 ASP A N   1 
ATOM   5421  C CA  . ASP A 1 736 ? 130.569 121.029 94.541  1.00 78.43  ?  725 ASP A CA  1 
ATOM   5422  C C   . ASP A 1 736 ? 131.538 120.099 93.836  1.00 78.43  ?  725 ASP A C   1 
ATOM   5423  O O   . ASP A 1 736 ? 131.487 118.884 94.020  1.00 78.43  ?  725 ASP A O   1 
ATOM   5424  C CB  . ASP A 1 736 ? 130.649 122.425 93.932  1.00 78.43  ?  725 ASP A CB  1 
ATOM   5425  C CG  . ASP A 1 736 ? 129.778 123.431 94.661  1.00 78.43  ?  725 ASP A CG  1 
ATOM   5426  O OD1 . ASP A 1 736 ? 129.102 123.043 95.637  1.00 78.43  ?  725 ASP A OD1 1 
ATOM   5427  O OD2 . ASP A 1 736 ? 129.772 124.614 94.260  1.00 78.43  -1 725 ASP A OD2 1 
ATOM   5428  N N   . ASN B 1 18  ? 141.546 126.040 93.399  1.00 63.62  ?  7   ASN B N   1 
ATOM   5429  C CA  . ASN B 1 18  ? 141.024 126.982 94.377  1.00 63.62  ?  7   ASN B CA  1 
ATOM   5430  C C   . ASN B 1 18  ? 141.468 128.399 94.041  1.00 63.62  ?  7   ASN B C   1 
ATOM   5431  O O   . ASN B 1 18  ? 142.607 128.626 93.621  1.00 63.62  ?  7   ASN B O   1 
ATOM   5432  C CB  . ASN B 1 18  ? 141.476 126.599 95.790  1.00 63.62  ?  7   ASN B CB  1 
ATOM   5433  C CG  . ASN B 1 18  ? 142.975 126.360 95.900  1.00 63.62  ?  7   ASN B CG  1 
ATOM   5434  O OD1 . ASN B 1 18  ? 143.788 127.152 95.431  1.00 63.62  ?  7   ASN B OD1 1 
ATOM   5435  N ND2 . ASN B 1 18  ? 143.345 125.256 96.541  1.00 63.62  ?  7   ASN B ND2 1 
ATOM   5436  N N   . GLN B 1 19  ? 140.572 129.357 94.207  1.00 56.82  ?  8   GLN B N   1 
ATOM   5437  C CA  . GLN B 1 19  ? 140.985 130.730 93.983  1.00 56.82  ?  8   GLN B CA  1 
ATOM   5438  C C   . GLN B 1 19  ? 140.114 131.703 94.737  1.00 56.82  ?  8   GLN B C   1 
ATOM   5439  O O   . GLN B 1 19  ? 138.900 131.711 94.573  1.00 56.82  ?  8   GLN B O   1 
ATOM   5440  C CB  . GLN B 1 19  ? 141.017 131.058 92.489  1.00 56.82  ?  8   GLN B CB  1 
ATOM   5441  C CG  . GLN B 1 19  ? 141.948 132.208 92.137  1.00 56.82  ?  8   GLN B CG  1 
ATOM   5442  C CD  . GLN B 1 19  ? 143.414 131.871 92.335  1.00 56.82  ?  8   GLN B CD  1 
ATOM   5443  O OE1 . GLN B 1 19  ? 144.265 132.759 92.389  1.00 56.82  ?  8   GLN B OE1 1 
ATOM   5444  N NE2 . GLN B 1 19  ? 143.719 130.585 92.439  1.00 56.82  ?  8   GLN B NE2 1 
ATOM   5445  N N   . TYR B 1 20  ? 140.736 132.506 95.582  1.00 47.39  ?  9   TYR B N   1 
ATOM   5446  C CA  . TYR B 1 20  ? 140.034 133.505 96.338  1.00 47.39  ?  9   TYR B CA  1 
ATOM   5447  C C   . TYR B 1 20  ? 140.022 134.724 95.456  1.00 47.39  ?  9   TYR B C   1 
ATOM   5448  O O   . TYR B 1 20  ? 141.004 135.454 95.393  1.00 47.39  ?  9   TYR B O   1 
ATOM   5449  C CB  . TYR B 1 20  ? 140.824 133.721 97.623  1.00 47.39  ?  9   TYR B CB  1 
ATOM   5450  C CG  . TYR B 1 20  ? 140.333 134.745 98.613  1.00 47.39  ?  9   TYR B CG  1 
ATOM   5451  C CD1 . TYR B 1 20  ? 139.916 134.355 99.877  1.00 47.39  ?  9   TYR B CD1 1 
ATOM   5452  C CD2 . TYR B 1 20  ? 140.350 136.099 98.318  1.00 47.39  ?  9   TYR B CD2 1 
ATOM   5453  C CE1 . TYR B 1 20  ? 139.494 135.280 100.805 1.00 47.39  ?  9   TYR B CE1 1 
ATOM   5454  C CE2 . TYR B 1 20  ? 139.928 137.033 99.241  1.00 47.39  ?  9   TYR B CE2 1 
ATOM   5455  C CZ  . TYR B 1 20  ? 139.501 136.615 100.481 1.00 47.39  ?  9   TYR B CZ  1 
ATOM   5456  O OH  . TYR B 1 20  ? 139.080 137.534 101.407 1.00 47.39  ?  9   TYR B OH  1 
ATOM   5457  N N   . ILE B 1 21  ? 138.930 134.938 94.738  1.00 49.48  ?  10  ILE B N   1 
ATOM   5458  C CA  . ILE B 1 21  ? 138.833 136.071 93.830  1.00 49.48  ?  10  ILE B CA  1 
ATOM   5459  C C   . ILE B 1 21  ? 137.791 137.067 94.309  1.00 49.48  ?  10  ILE B C   1 
ATOM   5460  O O   . ILE B 1 21  ? 136.619 136.732 94.431  1.00 49.48  ?  10  ILE B O   1 
ATOM   5461  C CB  . ILE B 1 21  ? 138.491 135.613 92.403  1.00 49.48  ?  10  ILE B CB  1 
ATOM   5462  C CG1 . ILE B 1 21  ? 139.516 134.584 91.927  1.00 49.48  ?  10  ILE B CG1 1 
ATOM   5463  C CG2 . ILE B 1 21  ? 138.433 136.801 91.460  1.00 49.48  ?  10  ILE B CG2 1 
ATOM   5464  C CD1 . ILE B 1 21  ? 139.250 134.054 90.539  1.00 49.48  ?  10  ILE B CD1 1 
ATOM   5465  N N   . VAL B 1 22  ? 138.219 138.291 94.590  1.00 47.89  ?  11  VAL B N   1 
ATOM   5466  C CA  . VAL B 1 22  ? 137.301 139.311 95.065  1.00 47.89  ?  11  VAL B CA  1 
ATOM   5467  C C   . VAL B 1 22  ? 137.471 140.626 94.336  1.00 47.89  ?  11  VAL B C   1 
ATOM   5468  O O   . VAL B 1 22  ? 138.590 141.073 94.123  1.00 47.89  ?  11  VAL B O   1 
ATOM   5469  C CB  . VAL B 1 22  ? 137.479 139.564 96.577  1.00 47.89  ?  11  VAL B CB  1 
ATOM   5470  C CG1 . VAL B 1 22  ? 136.666 140.767 97.025  1.00 47.89  ?  11  VAL B CG1 1 
ATOM   5471  C CG2 . VAL B 1 22  ? 137.098 138.328 97.379  1.00 47.89  ?  11  VAL B CG2 1 
ATOM   5472  N N   . ALA B 1 23  ? 136.369 141.238 93.931  1.00 49.73  ?  12  ALA B N   1 
ATOM   5473  C CA  . ALA B 1 23  ? 136.429 142.551 93.314  1.00 49.73  ?  12  ALA B CA  1 
ATOM   5474  C C   . ALA B 1 23  ? 135.322 143.377 93.924  1.00 49.73  ?  12  ALA B C   1 
ATOM   5475  O O   . ALA B 1 23  ? 134.161 143.214 93.575  1.00 49.73  ?  12  ALA B O   1 
ATOM   5476  C CB  . ALA B 1 23  ? 136.275 142.466 91.816  1.00 49.73  ?  12  ALA B CB  1 
ATOM   5477  N N   . ARG B 1 24  ? 135.670 144.255 94.850  1.00 48.32  ?  13  ARG B N   1 
ATOM   5478  C CA  . ARG B 1 24  ? 134.685 145.092 95.502  1.00 48.32  ?  13  ARG B CA  1 
ATOM   5479  C C   . ARG B 1 24  ? 135.283 146.458 95.710  1.00 48.32  ?  13  ARG B C   1 
ATOM   5480  O O   . ARG B 1 24  ? 136.486 146.616 95.662  1.00 48.32  ?  13  ARG B O   1 
ATOM   5481  C CB  . ARG B 1 24  ? 134.273 144.485 96.842  1.00 48.32  ?  13  ARG B CB  1 
ATOM   5482  C CG  . ARG B 1 24  ? 135.395 144.319 97.852  1.00 48.32  ?  13  ARG B CG  1 
ATOM   5483  C CD  . ARG B 1 24  ? 134.814 143.906 99.191  1.00 48.32  ?  13  ARG B CD  1 
ATOM   5484  N NE  . ARG B 1 24  ? 135.816 143.646 100.218 1.00 48.32  ?  13  ARG B NE  1 
ATOM   5485  C CZ  . ARG B 1 24  ? 136.296 144.567 101.044 1.00 48.32  ?  13  ARG B CZ  1 
ATOM   5486  N NH1 . ARG B 1 24  ? 135.878 145.821 100.953 1.00 48.32  1  13  ARG B NH1 1 
ATOM   5487  N NH2 . ARG B 1 24  ? 137.195 144.239 101.955 1.00 48.32  ?  13  ARG B NH2 1 
ATOM   5488  N N   . PRO B 1 25  ? 134.446 147.471 95.912  1.00 51.21  ?  14  PRO B N   1 
ATOM   5489  C CA  . PRO B 1 25  ? 135.021 148.780 96.237  1.00 51.21  ?  14  PRO B CA  1 
ATOM   5490  C C   . PRO B 1 25  ? 135.691 148.790 97.601  1.00 51.21  ?  14  PRO B C   1 
ATOM   5491  O O   . PRO B 1 25  ? 135.416 147.964 98.471  1.00 51.21  ?  14  PRO B O   1 
ATOM   5492  C CB  . PRO B 1 25  ? 133.807 149.713 96.212  1.00 51.21  ?  14  PRO B CB  1 
ATOM   5493  C CG  . PRO B 1 25  ? 132.655 148.838 96.458  1.00 51.21  ?  14  PRO B CG  1 
ATOM   5494  C CD  . PRO B 1 25  ? 132.979 147.533 95.819  1.00 51.21  ?  14  PRO B CD  1 
ATOM   5495  N N   . VAL B 1 26  ? 136.592 149.750 97.775  1.00 51.45  ?  15  VAL B N   1 
ATOM   5496  C CA  . VAL B 1 26  ? 137.221 149.973 99.069  1.00 51.45  ?  15  VAL B CA  1 
ATOM   5497  C C   . VAL B 1 26  ? 136.192 150.594 99.999  1.00 51.45  ?  15  VAL B C   1 
ATOM   5498  O O   . VAL B 1 26  ? 135.571 151.610 99.671  1.00 51.45  ?  15  VAL B O   1 
ATOM   5499  C CB  . VAL B 1 26  ? 138.461 150.869 98.926  1.00 51.45  ?  15  VAL B CB  1 
ATOM   5500  C CG1 . VAL B 1 26  ? 138.955 151.312 100.286 1.00 51.45  ?  15  VAL B CG1 1 
ATOM   5501  C CG2 . VAL B 1 26  ? 139.549 150.140 98.178  1.00 51.45  ?  15  VAL B CG2 1 
ATOM   5502  N N   . TYR B 1 27  ? 136.004 149.985 101.164 1.00 52.23  ?  16  TYR B N   1 
ATOM   5503  C CA  . TYR B 1 27  ? 134.893 150.320 102.043 1.00 52.23  ?  16  TYR B CA  1 
ATOM   5504  C C   . TYR B 1 27  ? 135.411 150.835 103.372 1.00 52.23  ?  16  TYR B C   1 
ATOM   5505  O O   . TYR B 1 27  ? 136.153 150.136 104.069 1.00 52.23  ?  16  TYR B O   1 
ATOM   5506  C CB  . TYR B 1 27  ? 133.995 149.105 102.274 1.00 52.23  ?  16  TYR B CB  1 
ATOM   5507  C CG  . TYR B 1 27  ? 132.899 148.941 101.254 1.00 52.23  ?  16  TYR B CG  1 
ATOM   5508  C CD1 . TYR B 1 27  ? 132.094 150.008 100.900 1.00 52.23  ?  16  TYR B CD1 1 
ATOM   5509  C CD2 . TYR B 1 27  ? 132.669 147.719 100.648 1.00 52.23  ?  16  TYR B CD2 1 
ATOM   5510  C CE1 . TYR B 1 27  ? 131.097 149.864 99.972  1.00 52.23  ?  16  TYR B CE1 1 
ATOM   5511  C CE2 . TYR B 1 27  ? 131.673 147.566 99.719  1.00 52.23  ?  16  TYR B CE2 1 
ATOM   5512  C CZ  . TYR B 1 27  ? 130.888 148.643 99.385  1.00 52.23  ?  16  TYR B CZ  1 
ATOM   5513  O OH  . TYR B 1 27  ? 129.887 148.500 98.455  1.00 52.23  ?  16  TYR B OH  1 
ATOM   5514  N N   . SER B 1 28  ? 134.907 151.976 103.816 1.00 51.79  ?  17  SER B N   1 
ATOM   5515  C CA  . SER B 1 28  ? 135.198 152.434 105.155 1.00 51.79  ?  17  SER B CA  1 
ATOM   5516  C C   . SER B 1 28  ? 133.945 151.975 105.882 1.00 51.79  ?  17  SER B C   1 
ATOM   5517  O O   . SER B 1 28  ? 132.935 151.721 105.239 1.00 51.79  ?  17  SER B O   1 
ATOM   5518  C CB  . SER B 1 28  ? 135.324 153.937 105.208 1.00 51.79  ?  17  SER B CB  1 
ATOM   5519  O OG  . SER B 1 28  ? 135.633 154.383 106.511 1.00 51.79  ?  17  SER B OG  1 
ATOM   5520  N N   . THR B 1 29  ? 133.975 151.851 107.198 1.00 53.93  ?  18  THR B N   1 
ATOM   5521  C CA  . THR B 1 29  ? 132.805 151.360 107.900 1.00 53.93  ?  18  THR B CA  1 
ATOM   5522  C C   . THR B 1 29  ? 131.594 152.256 107.607 1.00 53.93  ?  18  THR B C   1 
ATOM   5523  O O   . THR B 1 29  ? 130.493 151.758 107.400 1.00 53.93  ?  18  THR B O   1 
ATOM   5524  C CB  . THR B 1 29  ? 133.034 151.238 109.419 1.00 53.93  ?  18  THR B CB  1 
ATOM   5525  O OG1 . THR B 1 29  ? 133.255 152.536 109.978 1.00 53.93  ?  18  THR B OG1 1 
ATOM   5526  C CG2 . THR B 1 29  ? 134.235 150.355 109.704 1.00 53.93  ?  18  THR B CG2 1 
ATOM   5527  N N   . ASN B 1 30  ? 131.799 153.564 107.552 1.00 56.13  ?  19  ASN B N   1 
ATOM   5528  C CA  . ASN B 1 30  ? 130.712 154.488 107.240 1.00 56.13  ?  19  ASN B CA  1 
ATOM   5529  C C   . ASN B 1 30  ? 130.156 154.263 105.840 1.00 56.13  ?  19  ASN B C   1 
ATOM   5530  O O   . ASN B 1 30  ? 128.947 154.254 105.647 1.00 56.13  ?  19  ASN B O   1 
ATOM   5531  C CB  . ASN B 1 30  ? 131.187 155.935 107.384 1.00 56.13  ?  19  ASN B CB  1 
ATOM   5532  C CG  . ASN B 1 30  ? 131.454 156.327 108.824 1.00 56.13  ?  19  ASN B CG  1 
ATOM   5533  O OD1 . ASN B 1 30  ? 131.973 157.408 109.094 1.00 56.13  ?  19  ASN B OD1 1 
ATOM   5534  N ND2 . ASN B 1 30  ? 131.099 155.452 109.755 1.00 56.13  ?  19  ASN B ND2 1 
ATOM   5535  N N   . ALA B 1 31  ? 131.034 154.082 104.866 1.00 56.64  ?  20  ALA B N   1 
ATOM   5536  C CA  . ALA B 1 31  ? 130.605 153.847 103.494 1.00 56.64  ?  20  ALA B CA  1 
ATOM   5537  C C   . ALA B 1 31  ? 129.849 152.536 103.331 1.00 56.64  ?  20  ALA B C   1 
ATOM   5538  O O   . ALA B 1 31  ? 128.877 152.471 102.588 1.00 56.64  ?  20  ALA B O   1 
ATOM   5539  C CB  . ALA B 1 31  ? 131.805 153.874 102.568 1.00 56.64  ?  20  ALA B CB  1 
ATOM   5540  N N   . PHE B 1 32  ? 130.300 151.491 104.010 1.00 56.00  ?  21  PHE B N   1 
ATOM   5541  C CA  . PHE B 1 32  ? 129.630 150.210 103.914 1.00 56.00  ?  21  PHE B CA  1 
ATOM   5542  C C   . PHE B 1 32  ? 128.210 150.344 104.434 1.00 56.00  ?  21  PHE B C   1 
ATOM   5543  O O   . PHE B 1 32  ? 127.280 149.819 103.841 1.00 56.00  ?  21  PHE B O   1 
ATOM   5544  C CB  . PHE B 1 32  ? 130.387 149.135 104.687 1.00 56.00  ?  21  PHE B CB  1 
ATOM   5545  C CG  . PHE B 1 32  ? 129.773 147.774 104.574 1.00 56.00  ?  21  PHE B CG  1 
ATOM   5546  C CD1 . PHE B 1 32  ? 130.122 146.931 103.536 1.00 56.00  ?  21  PHE B CD1 1 
ATOM   5547  C CD2 . PHE B 1 32  ? 128.838 147.343 105.499 1.00 56.00  ?  21  PHE B CD2 1 
ATOM   5548  C CE1 . PHE B 1 32  ? 129.555 145.681 103.426 1.00 56.00  ?  21  PHE B CE1 1 
ATOM   5549  C CE2 . PHE B 1 32  ? 128.267 146.094 105.393 1.00 56.00  ?  21  PHE B CE2 1 
ATOM   5550  C CZ  . PHE B 1 32  ? 128.628 145.262 104.355 1.00 56.00  ?  21  PHE B CZ  1 
ATOM   5551  N N   . GLU B 1 33  ? 128.047 151.056 105.536 1.00 60.58  ?  22  GLU B N   1 
ATOM   5552  C CA  . GLU B 1 33  ? 126.726 151.240 106.122 1.00 60.58  ?  22  GLU B CA  1 
ATOM   5553  C C   . GLU B 1 33  ? 125.815 152.123 105.280 1.00 60.58  ?  22  GLU B C   1 
ATOM   5554  O O   . GLU B 1 33  ? 124.599 151.995 105.344 1.00 60.58  ?  22  GLU B O   1 
ATOM   5555  C CB  . GLU B 1 33  ? 126.861 151.816 107.528 1.00 60.58  ?  22  GLU B CB  1 
ATOM   5556  C CG  . GLU B 1 33  ? 127.571 150.878 108.490 1.00 60.58  ?  22  GLU B CG  1 
ATOM   5557  C CD  . GLU B 1 33  ? 128.030 151.570 109.756 1.00 60.58  ?  22  GLU B CD  1 
ATOM   5558  O OE1 . GLU B 1 33  ? 128.402 150.864 110.717 1.00 60.58  ?  22  GLU B OE1 1 
ATOM   5559  O OE2 . GLU B 1 33  ? 128.019 152.819 109.792 1.00 60.58  -1 22  GLU B OE2 1 
ATOM   5560  N N   . GLU B 1 34  ? 126.394 153.021 104.498 1.00 61.95  ?  23  GLU B N   1 
ATOM   5561  C CA  . GLU B 1 34  ? 125.604 153.900 103.655 1.00 61.95  ?  23  GLU B CA  1 
ATOM   5562  C C   . GLU B 1 34  ? 125.216 153.226 102.347 1.00 61.95  ?  23  GLU B C   1 
ATOM   5563  O O   . GLU B 1 34  ? 124.373 153.734 101.615 1.00 61.95  ?  23  GLU B O   1 
ATOM   5564  C CB  . GLU B 1 34  ? 126.370 155.188 103.373 1.00 61.95  ?  23  GLU B CB  1 
ATOM   5565  C CG  . GLU B 1 34  ? 127.423 155.065 102.289 1.00 61.95  ?  23  GLU B CG  1 
ATOM   5566  C CD  . GLU B 1 34  ? 128.407 156.216 102.306 1.00 61.95  ?  23  GLU B CD  1 
ATOM   5567  O OE1 . GLU B 1 34  ? 129.142 156.385 101.310 1.00 61.95  ?  23  GLU B OE1 1 
ATOM   5568  O OE2 . GLU B 1 34  ? 128.443 156.951 103.316 1.00 61.95  -1 23  GLU B OE2 1 
ATOM   5569  N N   . ASN B 1 35  ? 125.826 152.087 102.049 1.00 62.31  ?  24  ASN B N   1 
ATOM   5570  C CA  . ASN B 1 35  ? 125.517 151.368 100.822 1.00 62.31  ?  24  ASN B CA  1 
ATOM   5571  C C   . ASN B 1 35  ? 124.757 150.094 101.118 1.00 62.31  ?  24  ASN B C   1 
ATOM   5572  O O   . ASN B 1 35  ? 124.345 149.388 100.207 1.00 62.31  ?  24  ASN B O   1 
ATOM   5573  C CB  . ASN B 1 35  ? 126.799 151.048 100.065 1.00 62.31  ?  24  ASN B CB  1 
ATOM   5574  C CG  . ASN B 1 35  ? 127.588 152.292 99.716  1.00 62.31  ?  24  ASN B CG  1 
ATOM   5575  O OD1 . ASN B 1 35  ? 127.015 153.345 99.444  1.00 62.31  ?  24  ASN B OD1 1 
ATOM   5576  N ND2 . ASN B 1 35  ? 128.909 152.179 99.722  1.00 62.31  ?  24  ASN B ND2 1 
ATOM   5577  N N   . HIS B 1 36  ? 124.574 149.794 102.393 1.00 61.37  ?  25  HIS B N   1 
ATOM   5578  C CA  . HIS B 1 36  ? 123.863 148.595 102.774 1.00 61.37  ?  25  HIS B CA  1 
ATOM   5579  C C   . HIS B 1 36  ? 122.816 148.945 103.801 1.00 61.37  ?  25  HIS B C   1 
ATOM   5580  O O   . HIS B 1 36  ? 123.134 149.484 104.856 1.00 61.37  ?  25  HIS B O   1 
ATOM   5581  C CB  . HIS B 1 36  ? 124.838 147.547 103.311 1.00 61.37  ?  25  HIS B CB  1 
ATOM   5582  C CG  . HIS B 1 36  ? 125.882 147.146 102.318 1.00 61.37  ?  25  HIS B CG  1 
ATOM   5583  N ND1 . HIS B 1 36  ? 127.060 147.840 102.158 1.00 61.37  ?  25  HIS B ND1 1 
ATOM   5584  C CD2 . HIS B 1 36  ? 125.910 146.142 101.412 1.00 61.37  ?  25  HIS B CD2 1 
ATOM   5585  C CE1 . HIS B 1 36  ? 127.777 147.273 101.206 1.00 61.37  ?  25  HIS B CE1 1 
ATOM   5586  N NE2 . HIS B 1 36  ? 127.103 146.239 100.738 1.00 61.37  ?  25  HIS B NE2 1 
ATOM   5587  N N   . LYS B 1 37  ? 121.558 148.680 103.469 1.00 67.41  ?  26  LYS B N   1 
ATOM   5588  C CA  . LYS B 1 37  ? 120.460 148.986 104.376 1.00 67.41  ?  26  LYS B CA  1 
ATOM   5589  C C   . LYS B 1 37  ? 120.582 148.184 105.649 1.00 67.41  ?  26  LYS B C   1 
ATOM   5590  O O   . LYS B 1 37  ? 120.488 146.959 105.628 1.00 67.41  ?  26  LYS B O   1 
ATOM   5591  C CB  . LYS B 1 37  ? 119.122 148.690 103.705 1.00 67.41  ?  26  LYS B CB  1 
ATOM   5592  N N   . LYS B 1 38  ? 120.790 148.874 106.758 1.00 65.19  ?  27  LYS B N   1 
ATOM   5593  C CA  . LYS B 1 38  ? 120.932 148.187 108.022 1.00 65.19  ?  27  LYS B CA  1 
ATOM   5594  C C   . LYS B 1 38  ? 119.585 148.017 108.685 1.00 65.19  ?  27  LYS B C   1 
ATOM   5595  O O   . LYS B 1 38  ? 118.932 148.994 109.023 1.00 65.19  ?  27  LYS B O   1 
ATOM   5596  C CB  . LYS B 1 38  ? 121.877 148.952 108.940 1.00 65.19  ?  27  LYS B CB  1 
ATOM   5597  C CG  . LYS B 1 38  ? 122.584 148.067 109.952 1.00 65.19  ?  27  LYS B CG  1 
ATOM   5598  C CD  . LYS B 1 38  ? 123.763 148.783 110.583 1.00 65.19  ?  27  LYS B CD  1 
ATOM   5599  C CE  . LYS B 1 38  ? 124.509 147.864 111.536 1.00 65.19  ?  27  LYS B CE  1 
ATOM   5600  N NZ  . LYS B 1 38  ? 125.647 148.571 112.185 1.00 65.19  1  27  LYS B NZ  1 
ATOM   5601  N N   . THR B 1 39  ? 119.169 146.776 108.872 1.00 69.26  ?  28  THR B N   1 
ATOM   5602  C CA  . THR B 1 39  ? 117.917 146.512 109.548 1.00 69.26  ?  28  THR B CA  1 
ATOM   5603  C C   . THR B 1 39  ? 117.869 147.323 110.819 1.00 69.26  ?  28  THR B C   1 
ATOM   5604  O O   . THR B 1 39  ? 118.785 147.260 111.637 1.00 69.26  ?  28  THR B O   1 
ATOM   5605  C CB  . THR B 1 39  ? 117.778 145.026 109.908 1.00 69.26  ?  28  THR B CB  1 
ATOM   5606  O OG1 . THR B 1 39  ? 117.740 144.243 108.709 1.00 69.26  ?  28  THR B OG1 1 
ATOM   5607  C CG2 . THR B 1 39  ? 116.507 144.791 110.701 1.00 69.26  ?  28  THR B CG2 1 
ATOM   5608  N N   . GLY B 1 40  ? 116.810 148.096 110.989 1.00 77.33  ?  29  GLY B N   1 
ATOM   5609  C CA  . GLY B 1 40  ? 116.681 148.912 112.175 1.00 77.33  ?  29  GLY B CA  1 
ATOM   5610  C C   . GLY B 1 40  ? 116.179 148.034 113.288 1.00 77.33  ?  29  GLY B C   1 
ATOM   5611  O O   . GLY B 1 40  ? 115.061 147.528 113.224 1.00 77.33  ?  29  GLY B O   1 
ATOM   5612  N N   . ARG B 1 41  ? 117.000 147.835 114.308 1.00 83.78  ?  30  ARG B N   1 
ATOM   5613  C CA  . ARG B 1 41  ? 116.600 146.918 115.366 1.00 83.78  ?  30  ARG B CA  1 
ATOM   5614  C C   . ARG B 1 41  ? 116.491 147.681 116.675 1.00 83.78  ?  30  ARG B C   1 
ATOM   5615  O O   . ARG B 1 41  ? 117.448 148.341 117.092 1.00 83.78  ?  30  ARG B O   1 
ATOM   5616  C CB  . ARG B 1 41  ? 117.595 145.761 115.519 1.00 83.78  ?  30  ARG B CB  1 
ATOM   5617  C CG  . ARG B 1 41  ? 118.203 145.263 114.225 1.00 83.78  ?  30  ARG B CG  1 
ATOM   5618  C CD  . ARG B 1 41  ? 119.617 144.758 114.451 1.00 83.78  ?  30  ARG B CD  1 
ATOM   5619  N NE  . ARG B 1 41  ? 119.676 143.731 115.488 1.00 83.78  ?  30  ARG B NE  1 
ATOM   5620  C CZ  . ARG B 1 41  ? 120.803 143.288 116.036 1.00 83.78  ?  30  ARG B CZ  1 
ATOM   5621  N NH1 . ARG B 1 41  ? 121.970 143.778 115.644 1.00 83.78  1  30  ARG B NH1 1 
ATOM   5622  N NH2 . ARG B 1 41  ? 120.766 142.353 116.975 1.00 83.78  ?  30  ARG B NH2 1 
ATOM   5623  N N   . HIS B 1 42  ? 115.336 147.582 117.318 1.00 110.02 ?  31  HIS B N   1 
ATOM   5624  C CA  . HIS B 1 42  ? 115.137 148.246 118.598 1.00 110.02 ?  31  HIS B CA  1 
ATOM   5625  C C   . HIS B 1 42  ? 115.738 147.416 119.712 1.00 110.02 ?  31  HIS B C   1 
ATOM   5626  O O   . HIS B 1 42  ? 115.351 146.265 119.909 1.00 110.02 ?  31  HIS B O   1 
ATOM   5627  C CB  . HIS B 1 42  ? 113.649 148.452 118.856 1.00 110.02 ?  31  HIS B CB  1 
ATOM   5628  C CG  . HIS B 1 42  ? 113.318 148.710 120.291 1.00 110.02 ?  31  HIS B CG  1 
ATOM   5629  N ND1 . HIS B 1 42  ? 112.952 147.705 121.162 1.00 110.02 ?  31  HIS B ND1 1 
ATOM   5630  C CD2 . HIS B 1 42  ? 113.300 149.856 121.011 1.00 110.02 ?  31  HIS B CD2 1 
ATOM   5631  C CE1 . HIS B 1 42  ? 112.719 148.223 122.355 1.00 110.02 ?  31  HIS B CE1 1 
ATOM   5632  N NE2 . HIS B 1 42  ? 112.925 149.526 122.290 1.00 110.02 ?  31  HIS B NE2 1 
ATOM   5633  N N   . HIS B 1 43  ? 116.688 147.989 120.440 1.00 117.38 ?  32  HIS B N   1 
ATOM   5634  C CA  . HIS B 1 43  ? 117.279 147.282 121.566 1.00 117.38 ?  32  HIS B CA  1 
ATOM   5635  C C   . HIS B 1 43  ? 116.279 147.154 122.699 1.00 117.38 ?  32  HIS B C   1 
ATOM   5636  O O   . HIS B 1 43  ? 115.471 148.054 122.921 1.00 117.38 ?  32  HIS B O   1 
ATOM   5637  C CB  . HIS B 1 43  ? 118.523 148.012 122.062 1.00 117.38 ?  32  HIS B CB  1 
ATOM   5638  C CG  . HIS B 1 43  ? 118.763 147.857 123.532 1.00 117.38 ?  32  HIS B CG  1 
ATOM   5639  N ND1 . HIS B 1 43  ? 119.437 146.781 124.068 1.00 117.38 ?  32  HIS B ND1 1 
ATOM   5640  C CD2 . HIS B 1 43  ? 118.410 148.640 124.579 1.00 117.38 ?  32  HIS B CD2 1 
ATOM   5641  C CE1 . HIS B 1 43  ? 119.494 146.909 125.381 1.00 117.38 ?  32  HIS B CE1 1 
ATOM   5642  N NE2 . HIS B 1 43  ? 118.877 148.028 125.717 1.00 117.38 ?  32  HIS B NE2 1 
ATOM   5643  N N   . LYS B 1 44  ? 116.342 146.049 123.432 1.00 123.14 ?  33  LYS B N   1 
ATOM   5644  C CA  . LYS B 1 44  ? 115.432 145.847 124.549 1.00 123.14 ?  33  LYS B CA  1 
ATOM   5645  C C   . LYS B 1 44  ? 115.933 146.581 125.778 1.00 123.14 ?  33  LYS B C   1 
ATOM   5646  O O   . LYS B 1 44  ? 116.856 146.123 126.448 1.00 123.14 ?  33  LYS B O   1 
ATOM   5647  C CB  . LYS B 1 44  ? 115.274 144.357 124.847 1.00 123.14 ?  33  LYS B CB  1 
ATOM   5648  N N   . THR B 1 45  ? 115.327 147.722 126.076 1.00 127.31 ?  34  THR B N   1 
ATOM   5649  C CA  . THR B 1 45  ? 115.732 148.503 127.235 1.00 127.31 ?  34  THR B CA  1 
ATOM   5650  C C   . THR B 1 45  ? 115.355 147.820 128.538 1.00 127.31 ?  34  THR B C   1 
ATOM   5651  O O   . THR B 1 45  ? 114.396 147.057 128.589 1.00 127.31 ?  34  THR B O   1 
ATOM   5652  C CB  . THR B 1 45  ? 115.072 149.889 127.212 1.00 127.31 ?  34  THR B CB  1 
ATOM   5653  O OG1 . THR B 1 45  ? 113.655 149.746 127.370 1.00 127.31 ?  34  THR B OG1 1 
ATOM   5654  C CG2 . THR B 1 45  ? 115.363 150.588 125.894 1.00 127.31 ?  34  THR B CG2 1 
ATOM   5655  N N   . PHE B 1 46  ? 116.102 148.097 129.598 1.00 129.11 ?  35  PHE B N   1 
ATOM   5656  C CA  . PHE B 1 46  ? 115.777 147.526 130.898 1.00 129.11 ?  35  PHE B CA  1 
ATOM   5657  C C   . PHE B 1 46  ? 114.315 147.758 131.230 1.00 129.11 ?  35  PHE B C   1 
ATOM   5658  O O   . PHE B 1 46  ? 113.660 146.886 131.799 1.00 129.11 ?  35  PHE B O   1 
ATOM   5659  C CB  . PHE B 1 46  ? 116.662 148.138 131.986 1.00 129.11 ?  35  PHE B CB  1 
ATOM   5660  C CG  . PHE B 1 46  ? 116.261 147.755 133.379 1.00 129.11 ?  35  PHE B CG  1 
ATOM   5661  C CD1 . PHE B 1 46  ? 116.708 146.571 133.938 1.00 129.11 ?  35  PHE B CD1 1 
ATOM   5662  C CD2 . PHE B 1 46  ? 115.439 148.578 134.129 1.00 129.11 ?  35  PHE B CD2 1 
ATOM   5663  C CE1 . PHE B 1 46  ? 116.342 146.214 135.221 1.00 129.11 ?  35  PHE B CE1 1 
ATOM   5664  C CE2 . PHE B 1 46  ? 115.067 148.226 135.411 1.00 129.11 ?  35  PHE B CE2 1 
ATOM   5665  C CZ  . PHE B 1 46  ? 115.520 147.044 135.959 1.00 129.11 ?  35  PHE B CZ  1 
ATOM   5666  N N   . LEU B 1 47  ? 113.797 148.926 130.872 1.00 128.70 ?  36  LEU B N   1 
ATOM   5667  C CA  . LEU B 1 47  ? 112.419 149.256 131.203 1.00 128.70 ?  36  LEU B CA  1 
ATOM   5668  C C   . LEU B 1 47  ? 111.446 148.207 130.681 1.00 128.70 ?  36  LEU B C   1 
ATOM   5669  O O   . LEU B 1 47  ? 110.570 147.750 131.412 1.00 128.70 ?  36  LEU B O   1 
ATOM   5670  C CB  . LEU B 1 47  ? 112.057 150.623 130.631 1.00 128.70 ?  36  LEU B CB  1 
ATOM   5671  N N   . ASP B 1 48  ? 111.600 147.836 129.416 1.00 128.19 ?  37  ASP B N   1 
ATOM   5672  C CA  . ASP B 1 48  ? 110.719 146.842 128.824 1.00 128.19 ?  37  ASP B CA  1 
ATOM   5673  C C   . ASP B 1 48  ? 110.917 145.507 129.514 1.00 128.19 ?  37  ASP B C   1 
ATOM   5674  O O   . ASP B 1 48  ? 109.950 144.838 129.873 1.00 128.19 ?  37  ASP B O   1 
ATOM   5675  C CB  . ASP B 1 48  ? 111.006 146.714 127.328 1.00 128.19 ?  37  ASP B CB  1 
ATOM   5676  N N   . HIS B 1 49  ? 112.172 145.118 129.702 1.00 128.21 ?  38  HIS B N   1 
ATOM   5677  C CA  . HIS B 1 49  ? 112.465 143.857 130.358 1.00 128.21 ?  38  HIS B CA  1 
ATOM   5678  C C   . HIS B 1 49  ? 111.681 143.780 131.645 1.00 128.21 ?  38  HIS B C   1 
ATOM   5679  O O   . HIS B 1 49  ? 111.224 142.710 132.040 1.00 128.21 ?  38  HIS B O   1 
ATOM   5680  C CB  . HIS B 1 49  ? 113.955 143.744 130.659 1.00 128.21 ?  38  HIS B CB  1 
ATOM   5681  C CG  . HIS B 1 49  ? 114.809 143.604 129.440 1.00 128.21 ?  38  HIS B CG  1 
ATOM   5682  N ND1 . HIS B 1 49  ? 114.875 142.438 128.709 1.00 128.21 ?  38  HIS B ND1 1 
ATOM   5683  C CD2 . HIS B 1 49  ? 115.645 144.479 128.832 1.00 128.21 ?  38  HIS B CD2 1 
ATOM   5684  C CE1 . HIS B 1 49  ? 115.709 142.603 127.697 1.00 128.21 ?  38  HIS B CE1 1 
ATOM   5685  N NE2 . HIS B 1 49  ? 116.190 143.832 127.750 1.00 128.21 ?  38  HIS B NE2 1 
ATOM   5686  N N   . LEU B 1 50  ? 111.522 144.919 132.306 1.00 128.04 ?  39  LEU B N   1 
ATOM   5687  C CA  . LEU B 1 50  ? 110.801 144.956 133.567 1.00 128.04 ?  39  LEU B CA  1 
ATOM   5688  C C   . LEU B 1 50  ? 109.346 144.595 133.349 1.00 128.04 ?  39  LEU B C   1 
ATOM   5689  O O   . LEU B 1 50  ? 108.768 143.834 134.122 1.00 128.04 ?  39  LEU B O   1 
ATOM   5690  C CB  . LEU B 1 50  ? 110.917 146.346 134.197 1.00 128.04 ?  39  LEU B CB  1 
ATOM   5691  C CG  . LEU B 1 50  ? 110.090 146.673 135.441 1.00 128.04 ?  39  LEU B CG  1 
ATOM   5692  C CD1 . LEU B 1 50  ? 110.801 147.716 136.287 1.00 128.04 ?  39  LEU B CD1 1 
ATOM   5693  C CD2 . LEU B 1 50  ? 108.690 147.142 135.071 1.00 128.04 ?  39  LEU B CD2 1 
ATOM   5694  N N   . LYS B 1 51  ? 108.764 145.102 132.271 1.00 126.82 ?  40  LYS B N   1 
ATOM   5695  C CA  . LYS B 1 51  ? 107.356 144.835 131.991 1.00 126.82 ?  40  LYS B CA  1 
ATOM   5696  C C   . LYS B 1 51  ? 107.080 143.358 131.723 1.00 126.82 ?  40  LYS B C   1 
ATOM   5697  O O   . LYS B 1 51  ? 106.230 142.753 132.372 1.00 126.82 ?  40  LYS B O   1 
ATOM   5698  C CB  . LYS B 1 51  ? 106.879 145.674 130.807 1.00 126.82 ?  40  LYS B CB  1 
ATOM   5699  C CG  . LYS B 1 51  ? 105.399 145.512 130.510 1.00 126.82 ?  40  LYS B CG  1 
ATOM   5700  C CD  . LYS B 1 51  ? 104.908 146.564 129.531 1.00 126.82 ?  40  LYS B CD  1 
ATOM   5701  C CE  . LYS B 1 51  ? 103.402 146.476 129.348 1.00 126.82 ?  40  LYS B CE  1 
ATOM   5702  N NZ  . LYS B 1 51  ? 102.882 147.559 128.468 1.00 126.82 1  40  LYS B NZ  1 
ATOM   5703  N N   . VAL B 1 52  ? 107.799 142.776 130.770 1.00 126.40 ?  41  VAL B N   1 
ATOM   5704  C CA  . VAL B 1 52  ? 107.590 141.369 130.448 1.00 126.40 ?  41  VAL B CA  1 
ATOM   5705  C C   . VAL B 1 52  ? 107.818 140.553 131.708 1.00 126.40 ?  41  VAL B C   1 
ATOM   5706  O O   . VAL B 1 52  ? 107.203 139.504 131.896 1.00 126.40 ?  41  VAL B O   1 
ATOM   5707  C CB  . VAL B 1 52  ? 108.510 140.889 129.309 1.00 126.40 ?  41  VAL B CB  1 
ATOM   5708  C CG1 . VAL B 1 52  ? 109.969 141.149 129.645 1.00 126.40 ?  41  VAL B CG1 1 
ATOM   5709  C CG2 . VAL B 1 52  ? 108.274 139.416 129.016 1.00 126.40 ?  41  VAL B CG2 1 
ATOM   5710  N N   . CYS B 1 53  ? 108.688 141.041 132.582 1.00 125.40 ?  42  CYS B N   1 
ATOM   5711  C CA  . CYS B 1 53  ? 108.932 140.358 133.844 1.00 125.40 ?  42  CYS B CA  1 
ATOM   5712  C C   . CYS B 1 53  ? 107.654 140.256 134.662 1.00 125.40 ?  42  CYS B C   1 
ATOM   5713  O O   . CYS B 1 53  ? 107.382 139.219 135.261 1.00 125.40 ?  42  CYS B O   1 
ATOM   5714  C CB  . CYS B 1 53  ? 110.000 141.100 134.644 1.00 125.40 ?  42  CYS B CB  1 
ATOM   5715  S SG  . CYS B 1 53  ? 110.113 140.613 136.379 1.00 125.40 ?  42  CYS B SG  1 
ATOM   5716  N N   . CYS B 1 54  ? 106.867 141.325 134.685 1.00 121.94 ?  43  CYS B N   1 
ATOM   5717  C CA  . CYS B 1 54  ? 105.642 141.331 135.480 1.00 121.94 ?  43  CYS B CA  1 
ATOM   5718  C C   . CYS B 1 54  ? 104.416 141.049 134.619 1.00 121.94 ?  43  CYS B C   1 
ATOM   5719  O O   . CYS B 1 54  ? 103.354 141.628 134.836 1.00 121.94 ?  43  CYS B O   1 
ATOM   5720  C CB  . CYS B 1 54  ? 105.488 142.670 136.201 1.00 121.94 ?  43  CYS B CB  1 
ATOM   5721  S SG  . CYS B 1 54  ? 104.215 142.695 137.484 1.00 121.94 ?  43  CYS B SG  1 
ATOM   5722  N N   . SER B 1 55  ? 104.560 140.162 133.642 1.00 115.95 ?  44  SER B N   1 
ATOM   5723  C CA  . SER B 1 55  ? 103.449 139.850 132.745 1.00 115.95 ?  44  SER B CA  1 
ATOM   5724  C C   . SER B 1 55  ? 102.248 139.272 133.478 1.00 115.95 ?  44  SER B C   1 
ATOM   5725  O O   . SER B 1 55  ? 101.115 139.672 133.217 1.00 115.95 ?  44  SER B O   1 
ATOM   5726  C CB  . SER B 1 55  ? 103.907 138.868 131.664 1.00 115.95 ?  44  SER B CB  1 
ATOM   5727  O OG  . SER B 1 55  ? 102.825 138.478 130.838 1.00 115.95 ?  44  SER B OG  1 
ATOM   5728  N N   . CYS B 1 56  ? 102.488 138.329 134.381 1.00 112.20 ?  45  CYS B N   1 
ATOM   5729  C CA  . CYS B 1 56  ? 101.400 137.692 135.124 1.00 112.20 ?  45  CYS B CA  1 
ATOM   5730  C C   . CYS B 1 56  ? 100.485 136.886 134.211 1.00 112.20 ?  45  CYS B C   1 
ATOM   5731  O O   . CYS B 1 56  ? 99.319  136.668 134.537 1.00 112.20 ?  45  CYS B O   1 
ATOM   5732  C CB  . CYS B 1 56  ? 100.586 138.728 135.908 1.00 112.20 ?  45  CYS B CB  1 
ATOM   5733  S SG  . CYS B 1 56  ? 101.567 139.742 137.040 1.00 112.20 ?  45  CYS B SG  1 
ATOM   5734  N N   . SER B 1 57  ? 101.005 136.438 133.075 1.00 106.09 ?  46  SER B N   1 
ATOM   5735  C CA  . SER B 1 57  ? 100.215 135.591 132.188 1.00 106.09 ?  46  SER B CA  1 
ATOM   5736  C C   . SER B 1 57  ? 99.813  134.317 132.915 1.00 106.09 ?  46  SER B C   1 
ATOM   5737  O O   . SER B 1 57  ? 100.567 133.810 133.744 1.00 106.09 ?  46  SER B O   1 
ATOM   5738  C CB  . SER B 1 57  ? 101.010 135.248 130.931 1.00 106.09 ?  46  SER B CB  1 
ATOM   5739  O OG  . SER B 1 57  ? 100.385 134.210 130.196 1.00 106.09 ?  46  SER B OG  1 
ATOM   5740  N N   . PRO B 1 58  ? 98.619  133.791 132.609 1.00 103.72 ?  47  PRO B N   1 
ATOM   5741  C CA  . PRO B 1 58  ? 98.146  132.576 133.280 1.00 103.72 ?  47  PRO B CA  1 
ATOM   5742  C C   . PRO B 1 58  ? 99.109  131.423 133.064 1.00 103.72 ?  47  PRO B C   1 
ATOM   5743  O O   . PRO B 1 58  ? 99.479  130.749 134.023 1.00 103.72 ?  47  PRO B O   1 
ATOM   5744  C CB  . PRO B 1 58  ? 96.818  132.285 132.579 1.00 103.72 ?  47  PRO B CB  1 
ATOM   5745  C CG  . PRO B 1 58  ? 96.368  133.607 132.058 1.00 103.72 ?  47  PRO B CG  1 
ATOM   5746  C CD  . PRO B 1 58  ? 97.622  134.336 131.674 1.00 103.72 ?  47  PRO B CD  1 
ATOM   5747  N N   . GLN B 1 59  ? 99.527  131.233 131.818 1.00 100.57 ?  48  GLN B N   1 
ATOM   5748  C CA  . GLN B 1 59  ? 100.464 130.181 131.446 1.00 100.57 ?  48  GLN B CA  1 
ATOM   5749  C C   . GLN B 1 59  ? 101.831 130.419 132.089 1.00 100.57 ?  48  GLN B C   1 
ATOM   5750  O O   . GLN B 1 59  ? 102.553 129.477 132.380 1.00 100.57 ?  48  GLN B O   1 
ATOM   5751  C CB  . GLN B 1 59  ? 100.587 130.115 129.922 1.00 100.57 ?  48  GLN B CB  1 
ATOM   5752  C CG  . GLN B 1 59  ? 101.729 129.259 129.411 1.00 100.57 ?  48  GLN B CG  1 
ATOM   5753  C CD  . GLN B 1 59  ? 101.984 129.467 127.929 1.00 100.57 ?  48  GLN B CD  1 
ATOM   5754  O OE1 . GLN B 1 59  ? 103.098 129.264 127.444 1.00 100.57 ?  48  GLN B OE1 1 
ATOM   5755  N NE2 . GLN B 1 59  ? 100.951 129.884 127.202 1.00 100.57 ?  48  GLN B NE2 1 
ATOM   5756  N N   . LYS B 1 60  ? 102.197 131.682 132.274 1.00 100.56 ?  49  LYS B N   1 
ATOM   5757  C CA  . LYS B 1 60  ? 103.460 132.014 132.919 1.00 100.56 ?  49  LYS B CA  1 
ATOM   5758  C C   . LYS B 1 60  ? 103.489 131.499 134.348 1.00 100.56 ?  49  LYS B C   1 
ATOM   5759  O O   . LYS B 1 60  ? 104.459 130.865 134.761 1.00 100.56 ?  49  LYS B O   1 
ATOM   5760  C CB  . LYS B 1 60  ? 103.706 133.520 132.922 1.00 100.56 ?  49  LYS B CB  1 
ATOM   5761  C CG  . LYS B 1 60  ? 105.117 133.888 133.349 1.00 100.56 ?  49  LYS B CG  1 
ATOM   5762  C CD  . LYS B 1 60  ? 105.259 135.370 133.649 1.00 100.56 ?  49  LYS B CD  1 
ATOM   5763  C CE  . LYS B 1 60  ? 104.535 135.742 134.930 1.00 100.56 ?  49  LYS B CE  1 
ATOM   5764  N NZ  . LYS B 1 60  ? 104.891 137.116 135.380 1.00 100.56 1  49  LYS B NZ  1 
ATOM   5765  N N   . ALA B 1 61  ? 102.428 131.761 135.100 1.00 95.99  ?  50  ALA B N   1 
ATOM   5766  C CA  . ALA B 1 61  ? 102.377 131.333 136.496 1.00 95.99  ?  50  ALA B CA  1 
ATOM   5767  C C   . ALA B 1 61  ? 102.514 129.823 136.637 1.00 95.99  ?  50  ALA B C   1 
ATOM   5768  O O   . ALA B 1 61  ? 103.208 129.341 137.528 1.00 95.99  ?  50  ALA B O   1 
ATOM   5769  C CB  . ALA B 1 61  ? 101.086 131.802 137.144 1.00 95.99  ?  50  ALA B CB  1 
ATOM   5770  N N   . LYS B 1 62  ? 101.831 129.091 135.719 1.00 91.66  ?  51  LYS B N   1 
ATOM   5771  C CA  . LYS B 1 62  ? 101.905 127.638 135.756 1.00 91.66  ?  51  LYS B CA  1 
ATOM   5772  C C   . LYS B 1 62  ? 103.349 127.192 135.638 1.00 91.66  ?  51  LYS B C   1 
ATOM   5773  O O   . LYS B 1 62  ? 103.790 126.304 136.357 1.00 91.66  ?  51  LYS B O   1 
ATOM   5774  C CB  . LYS B 1 62  ? 101.071 127.014 134.641 1.00 91.66  ?  51  LYS B CB  1 
ATOM   5775  C CG  . LYS B 1 62  ? 101.164 125.501 134.584 1.00 91.66  ?  51  LYS B CG  1 
ATOM   5776  C CD  . LYS B 1 62  ? 100.351 124.945 133.427 1.00 91.66  ?  51  LYS B CD  1 
ATOM   5777  C CE  . LYS B 1 62  ? 100.359 123.426 133.437 1.00 91.66  ?  51  LYS B CE  1 
ATOM   5778  N NZ  . LYS B 1 62  ? 99.804  122.887 134.709 1.00 91.66  1  51  LYS B NZ  1 
ATOM   5779  N N   . ARG B 1 63  ? 104.096 127.806 134.770 1.00 91.99  ?  52  ARG B N   1 
ATOM   5780  C CA  . ARG B 1 63  ? 105.496 127.473 134.583 1.00 91.99  ?  52  ARG B CA  1 
ATOM   5781  C C   . ARG B 1 63  ? 106.281 127.723 135.851 1.00 91.99  ?  52  ARG B C   1 
ATOM   5782  O O   . ARG B 1 63  ? 107.052 126.874 136.283 1.00 91.99  ?  52  ARG B O   1 
ATOM   5783  C CB  . ARG B 1 63  ? 106.093 128.302 133.453 1.00 91.99  ?  52  ARG B CB  1 
ATOM   5784  C CG  . ARG B 1 63  ? 106.089 127.610 132.104 1.00 91.99  ?  52  ARG B CG  1 
ATOM   5785  C CD  . ARG B 1 63  ? 106.893 128.396 131.078 1.00 91.99  ?  52  ARG B CD  1 
ATOM   5786  N NE  . ARG B 1 63  ? 106.220 129.621 130.654 1.00 91.99  ?  52  ARG B NE  1 
ATOM   5787  C CZ  . ARG B 1 63  ? 106.427 130.820 131.191 1.00 91.99  ?  52  ARG B CZ  1 
ATOM   5788  N NH1 . ARG B 1 63  ? 105.767 131.872 130.730 1.00 91.99  1  52  ARG B NH1 1 
ATOM   5789  N NH2 . ARG B 1 63  ? 107.296 130.969 132.181 1.00 91.99  ?  52  ARG B NH2 1 
ATOM   5790  N N   . ILE B 1 64  ? 106.077 128.882 136.458 1.00 84.40  ?  53  ILE B N   1 
ATOM   5791  C CA  . ILE B 1 64  ? 106.822 129.232 137.653 1.00 84.40  ?  53  ILE B CA  1 
ATOM   5792  C C   . ILE B 1 64  ? 106.577 128.248 138.784 1.00 84.40  ?  53  ILE B C   1 
ATOM   5793  O O   . ILE B 1 64  ? 107.519 127.788 139.422 1.00 84.40  ?  53  ILE B O   1 
ATOM   5794  C CB  . ILE B 1 64  ? 106.455 130.645 138.139 1.00 84.40  ?  53  ILE B CB  1 
ATOM   5795  C CG1 . ILE B 1 64  ? 106.561 131.644 136.985 1.00 84.40  ?  53  ILE B CG1 1 
ATOM   5796  C CG2 . ILE B 1 64  ? 107.347 131.059 139.298 1.00 84.40  ?  53  ILE B CG2 1 
ATOM   5797  C CD1 . ILE B 1 64  ? 107.910 131.649 136.304 1.00 84.40  ?  53  ILE B CD1 1 
ATOM   5798  N N   . VAL B 1 65  ? 105.320 127.926 139.057 1.00 80.53  ?  54  VAL B N   1 
ATOM   5799  C CA  . VAL B 1 65  ? 105.032 127.048 140.184 1.00 80.53  ?  54  VAL B CA  1 
ATOM   5800  C C   . VAL B 1 65  ? 105.599 125.661 139.932 1.00 80.53  ?  54  VAL B C   1 
ATOM   5801  O O   . VAL B 1 65  ? 106.168 125.046 140.830 1.00 80.53  ?  54  VAL B O   1 
ATOM   5802  C CB  . VAL B 1 65  ? 103.523 126.965 140.492 1.00 80.53  ?  54  VAL B CB  1 
ATOM   5803  C CG1 . VAL B 1 65  ? 102.738 126.566 139.255 1.00 80.53  ?  54  VAL B CG1 1 
ATOM   5804  C CG2 . VAL B 1 65  ? 103.266 125.996 141.634 1.00 80.53  ?  54  VAL B CG2 1 
ATOM   5805  N N   . LEU B 1 66  ? 105.459 125.170 138.711 1.00 77.12  ?  55  LEU B N   1 
ATOM   5806  C CA  . LEU B 1 66  ? 106.010 123.870 138.373 1.00 77.12  ?  55  LEU B CA  1 
ATOM   5807  C C   . LEU B 1 66  ? 107.517 123.888 138.516 1.00 77.12  ?  55  LEU B C   1 
ATOM   5808  O O   . LEU B 1 66  ? 108.116 122.901 138.930 1.00 77.12  ?  55  LEU B O   1 
ATOM   5809  C CB  . LEU B 1 66  ? 105.624 123.476 136.950 1.00 77.12  ?  55  LEU B CB  1 
ATOM   5810  C CG  . LEU B 1 66  ? 104.306 122.717 136.787 1.00 77.12  ?  55  LEU B CG  1 
ATOM   5811  C CD1 . LEU B 1 66  ? 103.153 123.439 137.463 1.00 77.12  ?  55  LEU B CD1 1 
ATOM   5812  C CD2 . LEU B 1 66  ? 104.007 122.472 135.317 1.00 77.12  ?  55  LEU B CD2 1 
ATOM   5813  N N   . SER B 1 67  ? 108.137 125.006 138.170 1.00 71.48  ?  56  SER B N   1 
ATOM   5814  C CA  . SER B 1 67  ? 109.580 125.118 138.271 1.00 71.48  ?  56  SER B CA  1 
ATOM   5815  C C   . SER B 1 67  ? 110.047 125.071 139.718 1.00 71.48  ?  56  SER B C   1 
ATOM   5816  O O   . SER B 1 67  ? 111.144 124.598 139.997 1.00 71.48  ?  56  SER B O   1 
ATOM   5817  C CB  . SER B 1 67  ? 110.054 126.412 137.611 1.00 71.48  ?  56  SER B CB  1 
ATOM   5818  O OG  . SER B 1 67  ? 109.737 127.541 138.401 1.00 71.48  ?  56  SER B OG  1 
ATOM   5819  N N   . LEU B 1 68  ? 109.226 125.565 140.634 1.00 65.66  ?  57  LEU B N   1 
ATOM   5820  C CA  . LEU B 1 68  ? 109.605 125.613 142.039 1.00 65.66  ?  57  LEU B CA  1 
ATOM   5821  C C   . LEU B 1 68  ? 109.249 124.336 142.766 1.00 65.66  ?  57  LEU B C   1 
ATOM   5822  O O   . LEU B 1 68  ? 109.764 124.075 143.847 1.00 65.66  ?  57  LEU B O   1 
ATOM   5823  C CB  . LEU B 1 68  ? 108.927 126.796 142.716 1.00 65.66  ?  57  LEU B CB  1 
ATOM   5824  C CG  . LEU B 1 68  ? 109.196 128.152 142.066 1.00 65.66  ?  57  LEU B CG  1 
ATOM   5825  C CD1 . LEU B 1 68  ? 108.307 129.225 142.671 1.00 65.66  ?  57  LEU B CD1 1 
ATOM   5826  C CD2 . LEU B 1 68  ? 110.665 128.522 142.184 1.00 65.66  ?  57  LEU B CD2 1 
ATOM   5827  N N   . PHE B 1 69  ? 108.377 123.534 142.179 1.00 63.58  ?  58  PHE B N   1 
ATOM   5828  C CA  . PHE B 1 69  ? 108.014 122.262 142.771 1.00 63.58  ?  58  PHE B CA  1 
ATOM   5829  C C   . PHE B 1 69  ? 108.191 121.235 141.686 1.00 63.58  ?  58  PHE B C   1 
ATOM   5830  O O   . PHE B 1 69  ? 107.218 120.735 141.138 1.00 63.58  ?  58  PHE B O   1 
ATOM   5831  C CB  . PHE B 1 69  ? 106.580 122.297 143.289 1.00 63.58  ?  58  PHE B CB  1 
ATOM   5832  C CG  . PHE B 1 69  ? 106.359 121.472 144.519 1.00 63.58  ?  58  PHE B CG  1 
ATOM   5833  C CD1 . PHE B 1 69  ? 105.409 120.466 144.534 1.00 63.58  ?  58  PHE B CD1 1 
ATOM   5834  C CD2 . PHE B 1 69  ? 107.105 121.700 145.662 1.00 63.58  ?  58  PHE B CD2 1 
ATOM   5835  C CE1 . PHE B 1 69  ? 105.204 119.706 145.670 1.00 63.58  ?  58  PHE B CE1 1 
ATOM   5836  C CE2 . PHE B 1 69  ? 106.907 120.942 146.799 1.00 63.58  ?  58  PHE B CE2 1 
ATOM   5837  C CZ  . PHE B 1 69  ? 105.955 119.943 146.803 1.00 63.58  ?  58  PHE B CZ  1 
ATOM   5838  N N   . PRO B 1 70  ? 109.445 120.910 141.364 1.00 59.53  ?  59  PRO B N   1 
ATOM   5839  C CA  . PRO B 1 70  ? 109.714 119.993 140.250 1.00 59.53  ?  59  PRO B CA  1 
ATOM   5840  C C   . PRO B 1 70  ? 109.065 118.616 140.378 1.00 59.53  ?  59  PRO B C   1 
ATOM   5841  O O   . PRO B 1 70  ? 108.881 117.955 139.362 1.00 59.53  ?  59  PRO B O   1 
ATOM   5842  C CB  . PRO B 1 70  ? 111.241 119.864 140.276 1.00 59.53  ?  59  PRO B CB  1 
ATOM   5843  C CG  . PRO B 1 70  ? 111.719 121.109 140.941 1.00 59.53  ?  59  PRO B CG  1 
ATOM   5844  C CD  . PRO B 1 70  ? 110.684 121.415 141.978 1.00 59.53  ?  59  PRO B CD  1 
ATOM   5845  N N   . ILE B 1 71  ? 108.727 118.190 141.586 1.00 59.42  ?  60  ILE B N   1 
ATOM   5846  C CA  . ILE B 1 71  ? 108.152 116.867 141.782 1.00 59.42  ?  60  ILE B CA  1 
ATOM   5847  C C   . ILE B 1 71  ? 106.814 116.748 141.062 1.00 59.42  ?  60  ILE B C   1 
ATOM   5848  O O   . ILE B 1 71  ? 106.428 115.662 140.645 1.00 59.42  ?  60  ILE B O   1 
ATOM   5849  C CB  . ILE B 1 71  ? 107.996 116.530 143.282 1.00 59.42  ?  60  ILE B CB  1 
ATOM   5850  C CG1 . ILE B 1 71  ? 107.750 115.029 143.459 1.00 59.42  ?  60  ILE B CG1 1 
ATOM   5851  C CG2 . ILE B 1 71  ? 106.887 117.356 143.910 1.00 59.42  ?  60  ILE B CG2 1 
ATOM   5852  C CD1 . ILE B 1 71  ? 107.858 114.556 144.889 1.00 59.42  ?  60  ILE B CD1 1 
ATOM   5853  N N   . ALA B 1 72  ? 106.118 117.866 140.897 1.00 63.14  ?  61  ALA B N   1 
ATOM   5854  C CA  . ALA B 1 72  ? 104.825 117.865 140.214 1.00 63.14  ?  61  ALA B CA  1 
ATOM   5855  C C   . ALA B 1 72  ? 104.962 117.558 138.731 1.00 63.14  ?  61  ALA B C   1 
ATOM   5856  O O   . ALA B 1 72  ? 103.972 117.280 138.066 1.00 63.14  ?  61  ALA B O   1 
ATOM   5857  C CB  . ALA B 1 72  ? 104.128 119.198 140.418 1.00 63.14  ?  61  ALA B CB  1 
ATOM   5858  N N   . SER B 1 73  ? 106.178 117.606 138.209 1.00 65.29  ?  62  SER B N   1 
ATOM   5859  C CA  . SER B 1 73  ? 106.402 117.278 136.808 1.00 65.29  ?  62  SER B CA  1 
ATOM   5860  C C   . SER B 1 73  ? 106.936 115.866 136.600 1.00 65.29  ?  62  SER B C   1 
ATOM   5861  O O   . SER B 1 73  ? 106.401 115.125 135.784 1.00 65.29  ?  62  SER B O   1 
ATOM   5862  C CB  . SER B 1 73  ? 107.372 118.280 136.184 1.00 65.29  ?  62  SER B CB  1 
ATOM   5863  O OG  . SER B 1 73  ? 106.896 119.606 136.328 1.00 65.29  ?  62  SER B OG  1 
ATOM   5864  N N   . TRP B 1 74  ? 107.975 115.479 137.333 1.00 61.32  ?  63  TRP B N   1 
ATOM   5865  C CA  . TRP B 1 74  ? 108.594 114.169 137.107 1.00 61.32  ?  63  TRP B CA  1 
ATOM   5866  C C   . TRP B 1 74  ? 107.883 112.983 137.763 1.00 61.32  ?  63  TRP B C   1 
ATOM   5867  O O   . TRP B 1 74  ? 107.935 111.871 137.251 1.00 61.32  ?  63  TRP B O   1 
ATOM   5868  C CB  . TRP B 1 74  ? 110.077 114.187 137.512 1.00 61.32  ?  63  TRP B CB  1 
ATOM   5869  C CG  . TRP B 1 74  ? 110.371 114.380 138.971 1.00 61.32  ?  63  TRP B CG  1 
ATOM   5870  C CD1 . TRP B 1 74  ? 110.709 115.545 139.588 1.00 61.32  ?  63  TRP B CD1 1 
ATOM   5871  C CD2 . TRP B 1 74  ? 110.396 113.368 139.985 1.00 61.32  ?  63  TRP B CD2 1 
ATOM   5872  N NE1 . TRP B 1 74  ? 110.928 115.329 140.924 1.00 61.32  ?  63  TRP B NE1 1 
ATOM   5873  C CE2 . TRP B 1 74  ? 110.738 113.999 141.195 1.00 61.32  ?  63  TRP B CE2 1 
ATOM   5874  C CE3 . TRP B 1 74  ? 110.152 111.992 139.990 1.00 61.32  ?  63  TRP B CE3 1 
ATOM   5875  C CZ2 . TRP B 1 74  ? 110.845 113.304 142.397 1.00 61.32  ?  63  TRP B CZ2 1 
ATOM   5876  C CZ3 . TRP B 1 74  ? 110.255 111.304 141.182 1.00 61.32  ?  63  TRP B CZ3 1 
ATOM   5877  C CH2 . TRP B 1 74  ? 110.599 111.960 142.370 1.00 61.32  ?  63  TRP B CH2 1 
ATOM   5878  N N   . LEU B 1 75  ? 107.236 113.210 138.895 1.00 63.21  ?  64  LEU B N   1 
ATOM   5879  C CA  . LEU B 1 75  ? 106.553 112.120 139.576 1.00 63.21  ?  64  LEU B CA  1 
ATOM   5880  C C   . LEU B 1 75  ? 105.382 111.572 138.757 1.00 63.21  ?  64  LEU B C   1 
ATOM   5881  O O   . LEU B 1 75  ? 105.240 110.363 138.619 1.00 63.21  ?  64  LEU B O   1 
ATOM   5882  C CB  . LEU B 1 75  ? 106.079 112.544 140.962 1.00 63.21  ?  64  LEU B CB  1 
ATOM   5883  C CG  . LEU B 1 75  ? 105.598 111.394 141.842 1.00 63.21  ?  64  LEU B CG  1 
ATOM   5884  C CD1 . LEU B 1 75  ? 106.678 110.326 141.943 1.00 63.21  ?  64  LEU B CD1 1 
ATOM   5885  C CD2 . LEU B 1 75  ? 105.202 111.898 143.219 1.00 63.21  ?  64  LEU B CD2 1 
ATOM   5886  N N   . PRO B 1 76  ? 104.546 112.459 138.197 1.00 65.60  ?  65  PRO B N   1 
ATOM   5887  C CA  . PRO B 1 76  ? 103.424 112.003 137.374 1.00 65.60  ?  65  PRO B CA  1 
ATOM   5888  C C   . PRO B 1 76  ? 103.881 111.258 136.131 1.00 65.60  ?  65  PRO B C   1 
ATOM   5889  O O   . PRO B 1 76  ? 103.077 110.566 135.517 1.00 65.60  ?  65  PRO B O   1 
ATOM   5890  C CB  . PRO B 1 76  ? 102.735 113.311 136.977 1.00 65.60  ?  65  PRO B CB  1 
ATOM   5891  C CG  . PRO B 1 76  ? 103.108 114.275 138.045 1.00 65.60  ?  65  PRO B CG  1 
ATOM   5892  C CD  . PRO B 1 76  ? 104.518 113.919 138.391 1.00 65.60  ?  65  PRO B CD  1 
ATOM   5893  N N   . ALA B 1 77  ? 105.148 111.390 135.765 1.00 66.29  ?  66  ALA B N   1 
ATOM   5894  C CA  . ALA B 1 77  ? 105.674 110.725 134.581 1.00 66.29  ?  66  ALA B CA  1 
ATOM   5895  C C   . ALA B 1 77  ? 106.594 109.562 134.919 1.00 66.29  ?  66  ALA B C   1 
ATOM   5896  O O   . ALA B 1 77  ? 107.441 109.187 134.113 1.00 66.29  ?  66  ALA B O   1 
ATOM   5897  C CB  . ALA B 1 77  ? 106.417 111.729 133.726 1.00 66.29  ?  66  ALA B CB  1 
ATOM   5898  N N   . TYR B 1 78  ? 106.436 108.984 136.100 1.00 67.45  ?  67  TYR B N   1 
ATOM   5899  C CA  . TYR B 1 78  ? 107.330 107.911 136.529 1.00 67.45  ?  67  TYR B CA  1 
ATOM   5900  C C   . TYR B 1 78  ? 107.082 106.583 135.832 1.00 67.45  ?  67  TYR B C   1 
ATOM   5901  O O   . TYR B 1 78  ? 105.990 106.035 135.916 1.00 67.45  ?  67  TYR B O   1 
ATOM   5902  C CB  . TYR B 1 78  ? 107.218 107.726 138.044 1.00 67.45  ?  67  TYR B CB  1 
ATOM   5903  C CG  . TYR B 1 78  ? 108.271 106.824 138.639 1.00 67.45  ?  67  TYR B CG  1 
ATOM   5904  C CD1 . TYR B 1 78  ? 109.427 107.350 139.199 1.00 67.45  ?  67  TYR B CD1 1 
ATOM   5905  C CD2 . TYR B 1 78  ? 108.109 105.449 138.645 1.00 67.45  ?  67  TYR B CD2 1 
ATOM   5906  C CE1 . TYR B 1 78  ? 110.390 106.528 139.747 1.00 67.45  ?  67  TYR B CE1 1 
ATOM   5907  C CE2 . TYR B 1 78  ? 109.067 104.620 139.189 1.00 67.45  ?  67  TYR B CE2 1 
ATOM   5908  C CZ  . TYR B 1 78  ? 110.203 105.167 139.739 1.00 67.45  ?  67  TYR B CZ  1 
ATOM   5909  O OH  . TYR B 1 78  ? 111.153 104.341 140.283 1.00 67.45  ?  67  TYR B OH  1 
ATOM   5910  N N   . ARG B 1 79  ? 108.088 106.062 135.144 1.00 72.60  ?  68  ARG B N   1 
ATOM   5911  C CA  . ARG B 1 79  ? 107.986 104.770 134.495 1.00 72.60  ?  68  ARG B CA  1 
ATOM   5912  C C   . ARG B 1 79  ? 108.174 103.663 135.525 1.00 72.60  ?  68  ARG B C   1 
ATOM   5913  O O   . ARG B 1 79  ? 109.297 103.235 135.772 1.00 72.60  ?  68  ARG B O   1 
ATOM   5914  C CB  . ARG B 1 79  ? 109.054 104.661 133.419 1.00 72.60  ?  68  ARG B CB  1 
ATOM   5915  C CG  . ARG B 1 79  ? 109.203 105.903 132.560 1.00 72.60  ?  68  ARG B CG  1 
ATOM   5916  C CD  . ARG B 1 79  ? 110.430 105.783 131.678 1.00 72.60  ?  68  ARG B CD  1 
ATOM   5917  N NE  . ARG B 1 79  ? 110.397 104.560 130.885 1.00 72.60  ?  68  ARG B NE  1 
ATOM   5918  C CZ  . ARG B 1 79  ? 111.412 104.116 130.152 1.00 72.60  ?  68  ARG B CZ  1 
ATOM   5919  N NH1 . ARG B 1 79  ? 111.289 102.992 129.461 1.00 72.60  1  68  ARG B NH1 1 
ATOM   5920  N NH2 . ARG B 1 79  ? 112.550 104.793 130.117 1.00 72.60  ?  68  ARG B NH2 1 
ATOM   5921  N N   . LEU B 1 80  ? 107.085 103.192 136.123 1.00 73.80  ?  69  LEU B N   1 
ATOM   5922  C CA  . LEU B 1 80  ? 107.174 102.174 137.176 1.00 73.80  ?  69  LEU B CA  1 
ATOM   5923  C C   . LEU B 1 80  ? 107.882 100.888 136.773 1.00 73.80  ?  69  LEU B C   1 
ATOM   5924  O O   . LEU B 1 80  ? 108.770 100.426 137.476 1.00 73.80  ?  69  LEU B O   1 
ATOM   5925  C CB  . LEU B 1 80  ? 105.774 101.827 137.688 1.00 73.80  ?  69  LEU B CB  1 
ATOM   5926  C CG  . LEU B 1 80  ? 105.086 102.893 138.537 1.00 73.80  ?  69  LEU B CG  1 
ATOM   5927  C CD1 . LEU B 1 80  ? 103.639 102.511 138.804 1.00 73.80  ?  69  LEU B CD1 1 
ATOM   5928  C CD2 . LEU B 1 80  ? 105.839 103.097 139.841 1.00 73.80  ?  69  LEU B CD2 1 
ATOM   5929  N N   . LYS B 1 81  ? 107.487 100.303 135.656 1.00 76.66  ?  70  LYS B N   1 
ATOM   5930  C CA  . LYS B 1 81  ? 108.069 99.040  135.228 1.00 76.66  ?  70  LYS B CA  1 
ATOM   5931  C C   . LYS B 1 81  ? 109.560 99.131  134.961 1.00 76.66  ?  70  LYS B C   1 
ATOM   5932  O O   . LYS B 1 81  ? 110.275 98.139  135.079 1.00 76.66  ?  70  LYS B O   1 
ATOM   5933  C CB  . LYS B 1 81  ? 107.351 98.549  133.971 1.00 76.66  ?  70  LYS B CB  1 
ATOM   5934  C CG  . LYS B 1 81  ? 108.086 97.462  133.208 1.00 76.66  ?  70  LYS B CG  1 
ATOM   5935  C CD  . LYS B 1 81  ? 107.391 97.163  131.891 1.00 76.66  ?  70  LYS B CD  1 
ATOM   5936  C CE  . LYS B 1 81  ? 108.188 96.176  131.058 1.00 76.66  ?  70  LYS B CE  1 
ATOM   5937  N NZ  . LYS B 1 81  ? 107.490 95.850  129.784 1.00 76.66  1  70  LYS B NZ  1 
ATOM   5938  N N   . GLU B 1 82  ? 110.044 100.310 134.605 1.00 74.89  ?  71  GLU B N   1 
ATOM   5939  C CA  . GLU B 1 82  ? 111.451 100.429 134.246 1.00 74.89  ?  71  GLU B CA  1 
ATOM   5940  C C   . GLU B 1 82  ? 112.318 101.079 135.309 1.00 74.89  ?  71  GLU B C   1 
ATOM   5941  O O   . GLU B 1 82  ? 113.541 101.026 135.216 1.00 74.89  ?  71  GLU B O   1 
ATOM   5942  C CB  . GLU B 1 82  ? 111.585 101.224 132.944 1.00 74.89  ?  71  GLU B CB  1 
ATOM   5943  C CG  . GLU B 1 82  ? 110.886 100.598 131.748 1.00 74.89  ?  71  GLU B CG  1 
ATOM   5944  C CD  . GLU B 1 82  ? 109.378 100.765 131.787 1.00 74.89  ?  71  GLU B CD  1 
ATOM   5945  O OE1 . GLU B 1 82  ? 108.689 100.107 130.982 1.00 74.89  ?  71  GLU B OE1 1 
ATOM   5946  O OE2 . GLU B 1 82  ? 108.881 101.550 132.622 1.00 74.89  -1 71  GLU B OE2 1 
ATOM   5947  N N   . TRP B 1 83  ? 111.710 101.688 136.321 1.00 68.42  ?  72  TRP B N   1 
ATOM   5948  C CA  . TRP B 1 83  ? 112.507 102.427 137.297 1.00 68.42  ?  72  TRP B CA  1 
ATOM   5949  C C   . TRP B 1 83  ? 112.324 102.038 138.753 1.00 68.42  ?  72  TRP B C   1 
ATOM   5950  O O   . TRP B 1 83  ? 113.213 102.283 139.558 1.00 68.42  ?  72  TRP B O   1 
ATOM   5951  C CB  . TRP B 1 83  ? 112.190 103.917 137.169 1.00 68.42  ?  72  TRP B CB  1 
ATOM   5952  C CG  . TRP B 1 83  ? 112.626 104.547 135.904 1.00 68.42  ?  72  TRP B CG  1 
ATOM   5953  C CD1 . TRP B 1 83  ? 113.444 104.013 134.954 1.00 68.42  ?  72  TRP B CD1 1 
ATOM   5954  C CD2 . TRP B 1 83  ? 112.281 105.854 135.448 1.00 68.42  ?  72  TRP B CD2 1 
ATOM   5955  N NE1 . TRP B 1 83  ? 113.622 104.906 133.929 1.00 68.42  ?  72  TRP B NE1 1 
ATOM   5956  C CE2 . TRP B 1 83  ? 112.919 106.047 134.209 1.00 68.42  ?  72  TRP B CE2 1 
ATOM   5957  C CE3 . TRP B 1 83  ? 111.490 106.882 135.968 1.00 68.42  ?  72  TRP B CE3 1 
ATOM   5958  C CZ2 . TRP B 1 83  ? 112.792 107.225 133.484 1.00 68.42  ?  72  TRP B CZ2 1 
ATOM   5959  C CZ3 . TRP B 1 83  ? 111.364 108.048 135.246 1.00 68.42  ?  72  TRP B CZ3 1 
ATOM   5960  C CH2 . TRP B 1 83  ? 112.012 108.211 134.017 1.00 68.42  ?  72  TRP B CH2 1 
ATOM   5961  N N   . LEU B 1 84  ? 111.195 101.445 139.114 1.00 65.74  ?  73  LEU B N   1 
ATOM   5962  C CA  . LEU B 1 84  ? 110.941 101.171 140.529 1.00 65.74  ?  73  LEU B CA  1 
ATOM   5963  C C   . LEU B 1 84  ? 111.973 100.260 141.190 1.00 65.74  ?  73  LEU B C   1 
ATOM   5964  O O   . LEU B 1 84  ? 112.528 100.609 142.225 1.00 65.74  ?  73  LEU B O   1 
ATOM   5965  C CB  . LEU B 1 84  ? 109.541 100.587 140.724 1.00 65.74  ?  73  LEU B CB  1 
ATOM   5966  C CG  . LEU B 1 84  ? 109.078 100.570 142.179 1.00 65.74  ?  73  LEU B CG  1 
ATOM   5967  C CD1 . LEU B 1 84  ? 109.210 101.956 142.788 1.00 65.74  ?  73  LEU B CD1 1 
ATOM   5968  C CD2 . LEU B 1 84  ? 107.649 100.070 142.280 1.00 65.74  ?  73  LEU B CD2 1 
ATOM   5969  N N   . LEU B 1 85  ? 112.237 99.106  140.597 1.00 62.54  ?  74  LEU B N   1 
ATOM   5970  C CA  . LEU B 1 85  ? 113.178 98.178  141.190 1.00 62.54  ?  74  LEU B CA  1 
ATOM   5971  C C   . LEU B 1 85  ? 114.567 98.784  141.217 1.00 62.54  ?  74  LEU B C   1 
ATOM   5972  O O   . LEU B 1 85  ? 115.282 98.652  142.207 1.00 62.54  ?  74  LEU B O   1 
ATOM   5973  C CB  . LEU B 1 85  ? 113.189 96.862  140.421 1.00 62.54  ?  74  LEU B CB  1 
ATOM   5974  C CG  . LEU B 1 85  ? 114.093 95.779  141.005 1.00 62.54  ?  74  LEU B CG  1 
ATOM   5975  C CD1 . LEU B 1 85  ? 113.732 95.518  142.460 1.00 62.54  ?  74  LEU B CD1 1 
ATOM   5976  C CD2 . LEU B 1 85  ? 114.004 94.502  140.186 1.00 62.54  ?  74  LEU B CD2 1 
ATOM   5977  N N   . SER B 1 86  ? 114.953 99.448  140.135 1.00 59.99  ?  75  SER B N   1 
ATOM   5978  C CA  . SER B 1 86  ? 116.257 100.087 140.079 1.00 59.99  ?  75  SER B CA  1 
ATOM   5979  C C   . SER B 1 86  ? 116.341 101.103 141.188 1.00 59.99  ?  75  SER B C   1 
ATOM   5980  O O   . SER B 1 86  ? 117.237 101.047 142.022 1.00 59.99  ?  75  SER B O   1 
ATOM   5981  C CB  . SER B 1 86  ? 116.461 100.769 138.728 1.00 59.99  ?  75  SER B CB  1 
ATOM   5982  O OG  . SER B 1 86  ? 116.236 99.870  137.661 1.00 59.99  ?  75  SER B OG  1 
ATOM   5983  N N   . ASP B 1 87  ? 115.408 102.039 141.198 1.00 58.51  ?  76  ASP B N   1 
ATOM   5984  C CA  . ASP B 1 87  ? 115.365 103.051 142.245 1.00 58.51  ?  76  ASP B CA  1 
ATOM   5985  C C   . ASP B 1 87  ? 115.407 102.424 143.631 1.00 58.51  ?  76  ASP B C   1 
ATOM   5986  O O   . ASP B 1 87  ? 116.107 102.932 144.509 1.00 58.51  ?  76  ASP B O   1 
ATOM   5987  C CB  . ASP B 1 87  ? 114.116 103.914 142.096 1.00 58.51  ?  76  ASP B CB  1 
ATOM   5988  C CG  . ASP B 1 87  ? 114.307 105.041 141.114 1.00 58.51  ?  76  ASP B CG  1 
ATOM   5989  O OD1 . ASP B 1 87  ? 115.387 105.658 141.116 1.00 58.51  ?  76  ASP B OD1 1 
ATOM   5990  O OD2 . ASP B 1 87  ? 113.371 105.317 140.341 1.00 58.51  -1 76  ASP B OD2 1 
ATOM   5991  N N   . ILE B 1 88  ? 114.692 101.319 143.839 1.00 57.98  ?  77  ILE B N   1 
ATOM   5992  C CA  . ILE B 1 88  ? 114.709 100.661 145.141 1.00 57.98  ?  77  ILE B CA  1 
ATOM   5993  C C   . ILE B 1 88  ? 116.111 100.169 145.477 1.00 57.98  ?  77  ILE B C   1 
ATOM   5994  O O   . ILE B 1 88  ? 116.610 100.378 146.589 1.00 57.98  ?  77  ILE B O   1 
ATOM   5995  C CB  . ILE B 1 88  ? 113.685 99.511  145.173 1.00 57.98  ?  77  ILE B CB  1 
ATOM   5996  C CG1 . ILE B 1 88  ? 112.263 100.067 145.208 1.00 57.98  ?  77  ILE B CG1 1 
ATOM   5997  C CG2 . ILE B 1 88  ? 113.932 98.613  146.367 1.00 57.98  ?  77  ILE B CG2 1 
ATOM   5998  C CD1 . ILE B 1 88  ? 111.198 99.003  145.129 1.00 57.98  ?  77  ILE B CD1 1 
ATOM   5999  N N   . VAL B 1 89  ? 116.775 99.516  144.520 1.00 56.15  ?  78  VAL B N   1 
ATOM   6000  C CA  . VAL B 1 89  ? 118.101 98.956  144.783 1.00 56.15  ?  78  VAL B CA  1 
ATOM   6001  C C   . VAL B 1 89  ? 119.113 100.068 145.037 1.00 56.15  ?  78  VAL B C   1 
ATOM   6002  O O   . VAL B 1 89  ? 119.900 100.018 145.996 1.00 56.15  ?  78  VAL B O   1 
ATOM   6003  C CB  . VAL B 1 89  ? 118.535 98.050  143.619 1.00 56.15  ?  78  VAL B CB  1 
ATOM   6004  C CG1 . VAL B 1 89  ? 119.986 97.650  143.773 1.00 56.15  ?  78  VAL B CG1 1 
ATOM   6005  C CG2 . VAL B 1 89  ? 117.650 96.825  143.548 1.00 56.15  ?  78  VAL B CG2 1 
ATOM   6006  N N   . SER B 1 90  ? 119.116 101.088 144.175 1.00 54.72  ?  79  SER B N   1 
ATOM   6007  C CA  . SER B 1 90  ? 120.034 102.202 144.351 1.00 54.72  ?  79  SER B CA  1 
ATOM   6008  C C   . SER B 1 90  ? 119.757 102.945 145.649 1.00 54.72  ?  79  SER B C   1 
ATOM   6009  O O   . SER B 1 90  ? 120.683 103.448 146.292 1.00 54.72  ?  79  SER B O   1 
ATOM   6010  C CB  . SER B 1 90  ? 119.935 103.146 143.158 1.00 54.72  ?  79  SER B CB  1 
ATOM   6011  O OG  . SER B 1 90  ? 120.404 104.435 143.493 1.00 54.72  ?  79  SER B OG  1 
ATOM   6012  N N   . GLY B 1 91  ? 118.503 102.952 146.080 1.00 53.76  ?  80  GLY B N   1 
ATOM   6013  C CA  . GLY B 1 91  ? 118.140 103.619 147.316 1.00 53.76  ?  80  GLY B CA  1 
ATOM   6014  C C   . GLY B 1 91  ? 118.605 102.913 148.567 1.00 53.76  ?  80  GLY B C   1 
ATOM   6015  O O   . GLY B 1 91  ? 119.139 103.542 149.476 1.00 53.76  ?  80  GLY B O   1 
ATOM   6016  N N   . ILE B 1 92  ? 118.409 101.604 148.625 1.00 53.21  ?  81  ILE B N   1 
ATOM   6017  C CA  . ILE B 1 92  ? 118.855 100.835 149.774 1.00 53.21  ?  81  ILE B CA  1 
ATOM   6018  C C   . ILE B 1 92  ? 120.368 100.843 149.869 1.00 53.21  ?  81  ILE B C   1 
ATOM   6019  O O   . ILE B 1 92  ? 120.921 101.002 150.952 1.00 53.21  ?  81  ILE B O   1 
ATOM   6020  C CB  . ILE B 1 92  ? 118.344 99.388  149.712 1.00 53.21  ?  81  ILE B CB  1 
ATOM   6021  C CG1 . ILE B 1 92  ? 116.816 99.369  149.708 1.00 53.21  ?  81  ILE B CG1 1 
ATOM   6022  C CG2 . ILE B 1 92  ? 118.885 98.578  150.879 1.00 53.21  ?  81  ILE B CG2 1 
ATOM   6023  C CD1 . ILE B 1 92  ? 116.226 97.988  149.549 1.00 53.21  ?  81  ILE B CD1 1 
ATOM   6024  N N   . SER B 1 93  ? 121.042 100.694 148.740 1.00 53.45  ?  82  SER B N   1 
ATOM   6025  C CA  . SER B 1 93  ? 122.494 100.739 148.724 1.00 53.45  ?  82  SER B CA  1 
ATOM   6026  C C   . SER B 1 93  ? 123.031 102.088 149.170 1.00 53.45  ?  82  SER B C   1 
ATOM   6027  O O   . SER B 1 93  ? 123.929 102.153 150.001 1.00 53.45  ?  82  SER B O   1 
ATOM   6028  C CB  . SER B 1 93  ? 122.991 100.444 147.315 1.00 53.45  ?  82  SER B CB  1 
ATOM   6029  O OG  . SER B 1 93  ? 122.389 99.273  146.798 1.00 53.45  ?  82  SER B OG  1 
ATOM   6030  N N   . THR B 1 94  ? 122.479 103.164 148.628 1.00 53.73  ?  83  THR B N   1 
ATOM   6031  C CA  . THR B 1 94  ? 122.974 104.498 148.945 1.00 53.73  ?  83  THR B CA  1 
ATOM   6032  C C   . THR B 1 94  ? 122.655 104.875 150.377 1.00 53.73  ?  83  THR B C   1 
ATOM   6033  O O   . THR B 1 94  ? 123.479 105.462 151.065 1.00 53.73  ?  83  THR B O   1 
ATOM   6034  C CB  . THR B 1 94  ? 122.390 105.554 147.979 1.00 53.73  ?  83  THR B CB  1 
ATOM   6035  O OG1 . THR B 1 94  ? 122.557 105.109 146.629 1.00 53.73  ?  83  THR B OG1 1 
ATOM   6036  C CG2 . THR B 1 94  ? 123.089 106.887 148.156 1.00 53.73  ?  83  THR B CG2 1 
ATOM   6037  N N   . GLY B 1 95  ? 121.457 104.548 150.828 1.00 51.63  ?  84  GLY B N   1 
ATOM   6038  C CA  . GLY B 1 95  ? 121.086 104.817 152.206 1.00 51.63  ?  84  GLY B CA  1 
ATOM   6039  C C   . GLY B 1 95  ? 122.005 104.125 153.189 1.00 51.63  ?  84  GLY B C   1 
ATOM   6040  O O   . GLY B 1 95  ? 122.368 104.687 154.228 1.00 51.63  ?  84  GLY B O   1 
ATOM   6041  N N   . ILE B 1 96  ? 122.401 102.892 152.868 1.00 51.80  ?  85  ILE B N   1 
ATOM   6042  C CA  . ILE B 1 96  ? 123.370 102.199 153.707 1.00 51.80  ?  85  ILE B CA  1 
ATOM   6043  C C   . ILE B 1 96  ? 124.696 102.949 153.720 1.00 51.80  ?  85  ILE B C   1 
ATOM   6044  O O   . ILE B 1 96  ? 125.353 103.061 154.761 1.00 51.80  ?  85  ILE B O   1 
ATOM   6045  C CB  . ILE B 1 96  ? 123.533 100.744 153.237 1.00 51.80  ?  85  ILE B CB  1 
ATOM   6046  C CG1 . ILE B 1 96  ? 122.309 99.927  153.643 1.00 51.80  ?  85  ILE B CG1 1 
ATOM   6047  C CG2 . ILE B 1 96  ? 124.784 100.137 153.816 1.00 51.80  ?  85  ILE B CG2 1 
ATOM   6048  C CD1 . ILE B 1 96  ? 122.380 98.482  153.234 1.00 51.80  ?  85  ILE B CD1 1 
ATOM   6049  N N   . VAL B 1 97  ? 125.102 103.494 152.572 1.00 51.76  ?  86  VAL B N   1 
ATOM   6050  C CA  . VAL B 1 97  ? 126.322 104.299 152.547 1.00 51.76  ?  86  VAL B CA  1 
ATOM   6051  C C   . VAL B 1 97  ? 126.127 105.617 153.291 1.00 51.76  ?  86  VAL B C   1 
ATOM   6052  O O   . VAL B 1 97  ? 127.047 106.105 153.959 1.00 51.76  ?  86  VAL B O   1 
ATOM   6053  C CB  . VAL B 1 97  ? 126.768 104.523 151.090 1.00 51.76  ?  86  VAL B CB  1 
ATOM   6054  C CG1 . VAL B 1 97  ? 127.905 105.517 151.016 1.00 51.76  ?  86  VAL B CG1 1 
ATOM   6055  C CG2 . VAL B 1 97  ? 127.179 103.212 150.469 1.00 51.76  ?  86  VAL B CG2 1 
ATOM   6056  N N   . ALA B 1 98  ? 124.933 106.205 153.206 1.00 50.88  ?  87  ALA B N   1 
ATOM   6057  C CA  . ALA B 1 98  ? 124.690 107.520 153.780 1.00 50.88  ?  87  ALA B CA  1 
ATOM   6058  C C   . ALA B 1 98  ? 124.655 107.481 155.296 1.00 50.88  ?  87  ALA B C   1 
ATOM   6059  O O   . ALA B 1 98  ? 125.053 108.452 155.938 1.00 50.88  ?  87  ALA B O   1 
ATOM   6060  C CB  . ALA B 1 98  ? 123.378 108.092 153.247 1.00 50.88  ?  87  ALA B CB  1 
ATOM   6061  N N   . VAL B 1 99  ? 124.180 106.384 155.885 1.00 49.63  ?  88  VAL B N   1 
ATOM   6062  C CA  . VAL B 1 99  ? 124.218 106.256 157.342 1.00 49.63  ?  88  VAL B CA  1 
ATOM   6063  C C   . VAL B 1 99  ? 125.652 106.376 157.850 1.00 49.63  ?  88  VAL B C   1 
ATOM   6064  O O   . VAL B 1 99  ? 125.957 107.186 158.739 1.00 49.63  ?  88  VAL B O   1 
ATOM   6065  C CB  . VAL B 1 99  ? 123.578 104.926 157.774 1.00 49.63  ?  88  VAL B CB  1 
ATOM   6066  C CG1 . VAL B 1 99  ? 123.972 104.590 159.198 1.00 49.63  ?  88  VAL B CG1 1 
ATOM   6067  C CG2 . VAL B 1 99  ? 122.076 104.999 157.635 1.00 49.63  ?  88  VAL B CG2 1 
ATOM   6068  N N   . LEU B 1 100 ? 126.555 105.577 157.279 1.00 49.43  ?  89  LEU B N   1 
ATOM   6069  C CA  . LEU B 1 100 ? 127.945 105.568 157.723 1.00 49.43  ?  89  LEU B CA  1 
ATOM   6070  C C   . LEU B 1 100 ? 128.634 106.888 157.417 1.00 49.43  ?  89  LEU B C   1 
ATOM   6071  O O   . LEU B 1 100 ? 129.404 107.402 158.240 1.00 49.43  ?  89  LEU B O   1 
ATOM   6072  C CB  . LEU B 1 100 ? 128.688 104.415 157.055 1.00 49.43  ?  89  LEU B CB  1 
ATOM   6073  C CG  . LEU B 1 100 ? 128.005 103.053 157.141 1.00 49.43  ?  89  LEU B CG  1 
ATOM   6074  C CD1 . LEU B 1 100 ? 128.675 102.066 156.216 1.00 49.43  ?  89  LEU B CD1 1 
ATOM   6075  C CD2 . LEU B 1 100 ? 128.015 102.545 158.567 1.00 49.43  ?  89  LEU B CD2 1 
ATOM   6076  N N   . GLN B 1 101 ? 128.389 107.442 156.230 1.00 48.87  ?  90  GLN B N   1 
ATOM   6077  C CA  . GLN B 1 101 ? 128.958 108.741 155.904 1.00 48.87  ?  90  GLN B CA  1 
ATOM   6078  C C   . GLN B 1 101 ? 128.457 109.822 156.846 1.00 48.87  ?  90  GLN B C   1 
ATOM   6079  O O   . GLN B 1 101 ? 129.223 110.710 157.223 1.00 48.87  ?  90  GLN B O   1 
ATOM   6080  C CB  . GLN B 1 101 ? 128.645 109.103 154.457 1.00 48.87  ?  90  GLN B CB  1 
ATOM   6081  C CG  . GLN B 1 101 ? 129.387 108.272 153.443 1.00 48.87  ?  90  GLN B CG  1 
ATOM   6082  C CD  . GLN B 1 101 ? 129.597 109.008 152.150 1.00 48.87  ?  90  GLN B CD  1 
ATOM   6083  O OE1 . GLN B 1 101 ? 129.382 110.212 152.071 1.00 48.87  ?  90  GLN B OE1 1 
ATOM   6084  N NE2 . GLN B 1 101 ? 130.023 108.289 151.123 1.00 48.87  ?  90  GLN B NE2 1 
ATOM   6085  N N   . GLY B 1 102 ? 127.192 109.758 157.254 1.00 48.16  ?  91  GLY B N   1 
ATOM   6086  C CA  . GLY B 1 102 ? 126.686 110.728 158.203 1.00 48.16  ?  91  GLY B CA  1 
ATOM   6087  C C   . GLY B 1 102 ? 127.357 110.619 159.553 1.00 48.16  ?  91  GLY B C   1 
ATOM   6088  O O   . GLY B 1 102 ? 127.732 111.629 160.149 1.00 48.16  ?  91  GLY B O   1 
ATOM   6089  N N   . LEU B 1 103 ? 127.518 109.395 160.056 1.00 47.90  ?  92  LEU B N   1 
ATOM   6090  C CA  . LEU B 1 103 ? 128.235 109.214 161.317 1.00 47.90  ?  92  LEU B CA  1 
ATOM   6091  C C   . LEU B 1 103 ? 129.654 109.780 161.235 1.00 47.90  ?  92  LEU B C   1 
ATOM   6092  O O   . LEU B 1 103 ? 130.099 110.523 162.121 1.00 47.90  ?  92  LEU B O   1 
ATOM   6093  C CB  . LEU B 1 103 ? 128.263 107.736 161.697 1.00 47.90  ?  92  LEU B CB  1 
ATOM   6094  C CG  . LEU B 1 103 ? 126.928 107.049 161.986 1.00 47.90  ?  92  LEU B CG  1 
ATOM   6095  C CD1 . LEU B 1 103 ? 127.134 105.564 162.161 1.00 47.90  ?  92  LEU B CD1 1 
ATOM   6096  C CD2 . LEU B 1 103 ? 126.285 107.632 163.213 1.00 47.90  ?  92  LEU B CD2 1 
ATOM   6097  N N   . ALA B 1 104 ? 130.375 109.456 160.158 1.00 46.58  ?  93  ALA B N   1 
ATOM   6098  C CA  . ALA B 1 104 ? 131.748 109.934 160.022 1.00 46.58  ?  93  ALA B CA  1 
ATOM   6099  C C   . ALA B 1 104 ? 131.812 111.455 159.929 1.00 46.58  ?  93  ALA B C   1 
ATOM   6100  O O   . ALA B 1 104 ? 132.666 112.094 160.559 1.00 46.58  ?  93  ALA B O   1 
ATOM   6101  C CB  . ALA B 1 104 ? 132.401 109.298 158.799 1.00 46.58  ?  93  ALA B CB  1 
ATOM   6102  N N   . PHE B 1 105 ? 130.920 112.059 159.152 1.00 45.82  ?  94  PHE B N   1 
ATOM   6103  C CA  . PHE B 1 105 ? 130.983 113.501 158.973 1.00 45.82  ?  94  PHE B CA  1 
ATOM   6104  C C   . PHE B 1 105 ? 130.472 114.242 160.196 1.00 45.82  ?  94  PHE B C   1 
ATOM   6105  O O   . PHE B 1 105 ? 130.812 115.412 160.388 1.00 45.82  ?  94  PHE B O   1 
ATOM   6106  C CB  . PHE B 1 105 ? 130.207 113.907 157.723 1.00 45.82  ?  94  PHE B CB  1 
ATOM   6107  C CG  . PHE B 1 105 ? 130.654 113.195 156.481 1.00 45.82  ?  94  PHE B CG  1 
ATOM   6108  C CD1 . PHE B 1 105 ? 131.936 112.695 156.383 1.00 45.82  ?  94  PHE B CD1 1 
ATOM   6109  C CD2 . PHE B 1 105 ? 129.794 113.020 155.419 1.00 45.82  ?  94  PHE B CD2 1 
ATOM   6110  C CE1 . PHE B 1 105 ? 132.347 112.036 155.259 1.00 45.82  ?  94  PHE B CE1 1 
ATOM   6111  C CE2 . PHE B 1 105 ? 130.205 112.363 154.288 1.00 45.82  ?  94  PHE B CE2 1 
ATOM   6112  C CZ  . PHE B 1 105 ? 131.483 111.871 154.208 1.00 45.82  ?  94  PHE B CZ  1 
ATOM   6113  N N   . ALA B 1 106 ? 129.666 113.586 161.033 1.00 47.17  ?  95  ALA B N   1 
ATOM   6114  C CA  . ALA B 1 106 ? 129.337 114.161 162.330 1.00 47.17  ?  95  ALA B CA  1 
ATOM   6115  C C   . ALA B 1 106 ? 130.532 114.092 163.263 1.00 47.17  ?  95  ALA B C   1 
ATOM   6116  O O   . ALA B 1 106 ? 130.690 114.942 164.143 1.00 47.17  ?  95  ALA B O   1 
ATOM   6117  C CB  . ALA B 1 106 ? 128.139 113.440 162.939 1.00 47.17  ?  95  ALA B CB  1 
ATOM   6118  N N   . LEU B 1 107 ? 131.379 113.072 163.097 1.00 47.93  ?  96  LEU B N   1 
ATOM   6119  C CA  . LEU B 1 107 ? 132.673 113.096 163.777 1.00 47.93  ?  96  LEU B CA  1 
ATOM   6120  C C   . LEU B 1 107 ? 133.513 114.279 163.315 1.00 47.93  ?  96  LEU B C   1 
ATOM   6121  O O   . LEU B 1 107 ? 134.210 114.905 164.119 1.00 47.93  ?  96  LEU B O   1 
ATOM   6122  C CB  . LEU B 1 107 ? 133.435 111.795 163.543 1.00 47.93  ?  96  LEU B CB  1 
ATOM   6123  C CG  . LEU B 1 107 ? 132.967 110.534 164.256 1.00 47.93  ?  96  LEU B CG  1 
ATOM   6124  C CD1 . LEU B 1 107 ? 133.942 109.412 163.981 1.00 47.93  ?  96  LEU B CD1 1 
ATOM   6125  C CD2 . LEU B 1 107 ? 132.833 110.780 165.735 1.00 47.93  ?  96  LEU B CD2 1 
ATOM   6126  N N   . LEU B 1 108 ? 133.469 114.595 162.017 1.00 47.54  ?  97  LEU B N   1 
ATOM   6127  C CA  . LEU B 1 108 ? 134.256 115.720 161.510 1.00 47.54  ?  97  LEU B CA  1 
ATOM   6128  C C   . LEU B 1 108 ? 133.785 117.057 162.070 1.00 47.54  ?  97  LEU B C   1 
ATOM   6129  O O   . LEU B 1 108 ? 134.568 118.010 162.133 1.00 47.54  ?  97  LEU B O   1 
ATOM   6130  C CB  . LEU B 1 108 ? 134.210 115.759 159.984 1.00 47.54  ?  97  LEU B CB  1 
ATOM   6131  C CG  . LEU B 1 108 ? 135.118 114.792 159.230 1.00 47.54  ?  97  LEU B CG  1 
ATOM   6132  C CD1 . LEU B 1 108 ? 134.819 114.843 157.746 1.00 47.54  ?  97  LEU B CD1 1 
ATOM   6133  C CD2 . LEU B 1 108 ? 136.569 115.122 159.492 1.00 47.54  ?  97  LEU B CD2 1 
ATOM   6134  N N   . VAL B 1 109 ? 132.509 117.161 162.458 1.00 49.00  ?  98  VAL B N   1 
ATOM   6135  C CA  . VAL B 1 109 ? 131.970 118.400 163.013 1.00 49.00  ?  98  VAL B CA  1 
ATOM   6136  C C   . VAL B 1 109 ? 132.189 118.494 164.519 1.00 49.00  ?  98  VAL B C   1 
ATOM   6137  O O   . VAL B 1 109 ? 132.052 119.584 165.091 1.00 49.00  ?  98  VAL B O   1 
ATOM   6138  C CB  . VAL B 1 109 ? 130.472 118.520 162.638 1.00 49.00  ?  98  VAL B CB  1 
ATOM   6139  C CG1 . VAL B 1 109 ? 129.861 119.805 163.151 1.00 49.00  ?  98  VAL B CG1 1 
ATOM   6140  C CG2 . VAL B 1 109 ? 130.309 118.468 161.144 1.00 49.00  ?  98  VAL B CG2 1 
ATOM   6141  N N   . ASP B 1 110 ? 132.572 117.393 165.166 1.00 53.76  ?  99  ASP B N   1 
ATOM   6142  C CA  . ASP B 1 110 ? 132.776 117.328 166.616 1.00 53.76  ?  99  ASP B CA  1 
ATOM   6143  C C   . ASP B 1 110 ? 131.452 117.490 167.359 1.00 53.76  ?  99  ASP B C   1 
ATOM   6144  O O   . ASP B 1 110 ? 131.341 118.237 168.331 1.00 53.76  ?  99  ASP B O   1 
ATOM   6145  C CB  . ASP B 1 110 ? 133.808 118.357 167.088 1.00 53.76  ?  99  ASP B CB  1 
ATOM   6146  C CG  . ASP B 1 110 ? 134.492 117.954 168.381 1.00 53.76  ?  99  ASP B CG  1 
ATOM   6147  O OD1 . ASP B 1 110 ? 135.721 118.140 168.482 1.00 53.76  ?  99  ASP B OD1 1 
ATOM   6148  O OD2 . ASP B 1 110 ? 133.806 117.453 169.295 1.00 53.76  -1 99  ASP B OD2 1 
ATOM   6149  N N   . ILE B 1 111 ? 130.439 116.773 166.886 1.00 52.01  ?  100 ILE B N   1 
ATOM   6150  C CA  . ILE B 1 111 ? 129.159 116.653 167.580 1.00 52.01  ?  100 ILE B CA  1 
ATOM   6151  C C   . ILE B 1 111 ? 128.812 115.176 167.689 1.00 52.01  ?  100 ILE B C   1 
ATOM   6152  O O   . ILE B 1 111 ? 129.440 114.333 167.035 1.00 52.01  ?  100 ILE B O   1 
ATOM   6153  C CB  . ILE B 1 111 ? 128.032 117.419 166.856 1.00 52.01  ?  100 ILE B CB  1 
ATOM   6154  C CG1 . ILE B 1 111 ? 127.887 116.940 165.415 1.00 52.01  ?  100 ILE B CG1 1 
ATOM   6155  C CG2 . ILE B 1 111 ? 128.293 118.910 166.885 1.00 52.01  ?  100 ILE B CG2 1 
ATOM   6156  C CD1 . ILE B 1 111 ? 126.857 117.700 164.636 1.00 52.01  ?  100 ILE B CD1 1 
ATOM   6157  N N   . PRO B 1 112 ? 127.851 114.827 168.541 1.00 54.98  ?  101 PRO B N   1 
ATOM   6158  C CA  . PRO B 1 112 ? 127.384 113.438 168.600 1.00 54.98  ?  101 PRO B CA  1 
ATOM   6159  C C   . PRO B 1 112 ? 126.993 112.935 167.222 1.00 54.98  ?  101 PRO B C   1 
ATOM   6160  O O   . PRO B 1 112 ? 126.564 113.719 166.365 1.00 54.98  ?  101 PRO B O   1 
ATOM   6161  C CB  . PRO B 1 112 ? 126.173 113.517 169.535 1.00 54.98  ?  101 PRO B CB  1 
ATOM   6162  C CG  . PRO B 1 112 ? 126.519 114.613 170.456 1.00 54.98  ?  101 PRO B CG  1 
ATOM   6163  C CD  . PRO B 1 112 ? 127.306 115.621 169.658 1.00 54.98  ?  101 PRO B CD  1 
ATOM   6164  N N   . PRO B 1 113 ? 127.129 111.631 166.966 1.00 54.76  ?  102 PRO B N   1 
ATOM   6165  C CA  . PRO B 1 113 ? 127.026 111.137 165.586 1.00 54.76  ?  102 PRO B CA  1 
ATOM   6166  C C   . PRO B 1 113 ? 125.608 110.950 165.060 1.00 54.76  ?  102 PRO B C   1 
ATOM   6167  O O   . PRO B 1 113 ? 125.455 110.679 163.863 1.00 54.76  ?  102 PRO B O   1 
ATOM   6168  C CB  . PRO B 1 113 ? 127.774 109.799 165.646 1.00 54.76  ?  102 PRO B CB  1 
ATOM   6169  C CG  . PRO B 1 113 ? 127.631 109.350 167.042 1.00 54.76  ?  102 PRO B CG  1 
ATOM   6170  C CD  . PRO B 1 113 ? 127.533 110.573 167.906 1.00 54.76  ?  102 PRO B CD  1 
ATOM   6171  N N   . VAL B 1 114 ? 124.611 110.940 165.937 1.00 53.29  ?  103 VAL B N   1 
ATOM   6172  C CA  . VAL B 1 114 ? 123.224 110.763 165.528 1.00 53.29  ?  103 VAL B CA  1 
ATOM   6173  C C   . VAL B 1 114 ? 122.765 112.000 164.788 1.00 53.29  ?  103 VAL B C   1 
ATOM   6174  O O   . VAL B 1 114 ? 121.778 111.972 164.059 1.00 53.29  ?  103 VAL B O   1 
ATOM   6175  C CB  . VAL B 1 114 ? 122.312 110.499 166.741 1.00 53.29  ?  103 VAL B CB  1 
ATOM   6176  C CG1 . VAL B 1 114 ? 122.259 111.720 167.645 1.00 53.29  ?  103 VAL B CG1 1 
ATOM   6177  C CG2 . VAL B 1 114 ? 120.915 110.103 166.289 1.00 53.29  ?  103 VAL B CG2 1 
ATOM   6178  N N   . TYR B 1 115 ? 123.480 113.095 164.981 1.00 51.41  ?  104 TYR B N   1 
ATOM   6179  C CA  . TYR B 1 115 ? 123.160 114.317 164.282 1.00 51.41  ?  104 TYR B CA  1 
ATOM   6180  C C   . TYR B 1 115 ? 123.585 114.174 162.845 1.00 51.41  ?  104 TYR B C   1 
ATOM   6181  O O   . TYR B 1 115 ? 123.059 114.863 161.974 1.00 51.41  ?  104 TYR B O   1 
ATOM   6182  C CB  . TYR B 1 115 ? 123.837 115.492 164.977 1.00 51.41  ?  104 TYR B CB  1 
ATOM   6183  C CG  . TYR B 1 115 ? 123.280 115.722 166.358 1.00 51.41  ?  104 TYR B CG  1 
ATOM   6184  C CD1 . TYR B 1 115 ? 122.104 116.434 166.537 1.00 51.41  ?  104 TYR B CD1 1 
ATOM   6185  C CD2 . TYR B 1 115 ? 123.910 115.205 167.479 1.00 51.41  ?  104 TYR B CD2 1 
ATOM   6186  C CE1 . TYR B 1 115 ? 121.578 116.637 167.794 1.00 51.41  ?  104 TYR B CE1 1 
ATOM   6187  C CE2 . TYR B 1 115 ? 123.391 115.403 168.742 1.00 51.41  ?  104 TYR B CE2 1 
ATOM   6188  C CZ  . TYR B 1 115 ? 122.224 116.120 168.892 1.00 51.41  ?  104 TYR B CZ  1 
ATOM   6189  O OH  . TYR B 1 115 ? 121.701 116.325 170.146 1.00 51.41  ?  104 TYR B OH  1 
ATOM   6190  N N   . GLY B 1 116 ? 124.537 113.287 162.583 1.00 49.79  ?  105 GLY B N   1 
ATOM   6191  C CA  . GLY B 1 116 ? 124.935 113.015 161.218 1.00 49.79  ?  105 GLY B CA  1 
ATOM   6192  C C   . GLY B 1 116 ? 123.798 112.302 160.537 1.00 49.79  ?  105 GLY B C   1 
ATOM   6193  O O   . GLY B 1 116 ? 123.566 112.497 159.354 1.00 49.79  ?  105 GLY B O   1 
ATOM   6194  N N   . LEU B 1 117 ? 123.098 111.459 161.277 1.00 48.76  ?  106 LEU B N   1 
ATOM   6195  C CA  . LEU B 1 117 ? 121.939 110.774 160.736 1.00 48.76  ?  106 LEU B CA  1 
ATOM   6196  C C   . LEU B 1 117 ? 120.843 111.772 160.404 1.00 48.76  ?  106 LEU B C   1 
ATOM   6197  O O   . LEU B 1 117 ? 120.170 111.631 159.392 1.00 48.76  ?  106 LEU B O   1 
ATOM   6198  C CB  . LEU B 1 117 ? 121.446 109.730 161.730 1.00 48.76  ?  106 LEU B CB  1 
ATOM   6199  C CG  . LEU B 1 117 ? 122.402 108.579 162.027 1.00 48.76  ?  106 LEU B CG  1 
ATOM   6200  C CD1 . LEU B 1 117 ? 121.707 107.560 162.911 1.00 48.76  ?  106 LEU B CD1 1 
ATOM   6201  C CD2 . LEU B 1 117 ? 122.870 107.933 160.732 1.00 48.76  ?  106 LEU B CD2 1 
ATOM   6202  N N   . TYR B 1 118 ? 120.666 112.780 161.245 1.00 48.77  ?  107 TYR B N   1 
ATOM   6203  C CA  . TYR B 1 118 ? 119.690 113.825 160.968 1.00 48.77  ?  107 TYR B CA  1 
ATOM   6204  C C   . TYR B 1 118 ? 120.094 114.579 159.722 1.00 48.77  ?  107 TYR B C   1 
ATOM   6205  O O   . TYR B 1 118 ? 119.254 114.915 158.897 1.00 48.77  ?  107 TYR B O   1 
ATOM   6206  C CB  . TYR B 1 118 ? 119.594 114.805 162.134 1.00 48.77  ?  107 TYR B CB  1 
ATOM   6207  C CG  . TYR B 1 118 ? 119.201 114.211 163.464 1.00 48.77  ?  107 TYR B CG  1 
ATOM   6208  C CD1 . TYR B 1 118 ? 118.247 113.210 163.550 1.00 48.77  ?  107 TYR B CD1 1 
ATOM   6209  C CD2 . TYR B 1 118 ? 119.767 114.678 164.640 1.00 48.77  ?  107 TYR B CD2 1 
ATOM   6210  C CE1 . TYR B 1 118 ? 117.884 112.676 164.770 1.00 48.77  ?  107 TYR B CE1 1 
ATOM   6211  C CE2 . TYR B 1 118 ? 119.412 114.152 165.863 1.00 48.77  ?  107 TYR B CE2 1 
ATOM   6212  C CZ  . TYR B 1 118 ? 118.469 113.154 165.923 1.00 48.77  ?  107 TYR B CZ  1 
ATOM   6213  O OH  . TYR B 1 118 ? 118.113 112.630 167.142 1.00 48.77  ?  107 TYR B OH  1 
ATOM   6214  N N   . ALA B 1 119 ? 121.388 114.845 159.583 1.00 46.47  ?  108 ALA B N   1 
ATOM   6215  C CA  . ALA B 1 119 ? 121.902 115.548 158.416 1.00 46.47  ?  108 ALA B CA  1 
ATOM   6216  C C   . ALA B 1 119 ? 121.722 114.748 157.138 1.00 46.47  ?  108 ALA B C   1 
ATOM   6217  O O   . ALA B 1 119 ? 121.684 115.315 156.057 1.00 46.47  ?  108 ALA B O   1 
ATOM   6218  C CB  . ALA B 1 119 ? 123.369 115.877 158.629 1.00 46.47  ?  108 ALA B CB  1 
ATOM   6219  N N   . SER B 1 120 ? 121.637 113.430 157.256 1.00 47.29  ?  109 SER B N   1 
ATOM   6220  C CA  . SER B 1 120 ? 121.452 112.574 156.090 1.00 47.29  ?  109 SER B CA  1 
ATOM   6221  C C   . SER B 1 120 ? 119.986 112.290 155.799 1.00 47.29  ?  109 SER B C   1 
ATOM   6222  O O   . SER B 1 120 ? 119.670 111.570 154.861 1.00 47.29  ?  109 SER B O   1 
ATOM   6223  C CB  . SER B 1 120 ? 122.187 111.247 156.283 1.00 47.29  ?  109 SER B CB  1 
ATOM   6224  O OG  . SER B 1 120 ? 123.569 111.451 156.495 1.00 47.29  ?  109 SER B OG  1 
ATOM   6225  N N   . PHE B 1 121 ? 119.087 112.841 156.600 1.00 47.62  ?  110 PHE B N   1 
ATOM   6226  C CA  . PHE B 1 121 ? 117.673 112.560 156.415 1.00 47.62  ?  110 PHE B CA  1 
ATOM   6227  C C   . PHE B 1 121 ? 116.865 113.749 155.895 1.00 47.62  ?  110 PHE B C   1 
ATOM   6228  O O   . PHE B 1 121 ? 116.007 113.574 155.039 1.00 47.62  ?  110 PHE B O   1 
ATOM   6229  C CB  . PHE B 1 121 ? 117.074 112.056 157.726 1.00 47.62  ?  110 PHE B CB  1 
ATOM   6230  C CG  . PHE B 1 121 ? 115.586 111.888 157.687 1.00 47.62  ?  110 PHE B CG  1 
ATOM   6231  C CD1 . PHE B 1 121 ? 115.018 110.785 157.078 1.00 47.62  ?  110 PHE B CD1 1 
ATOM   6232  C CD2 . PHE B 1 121 ? 114.757 112.835 158.260 1.00 47.62  ?  110 PHE B CD2 1 
ATOM   6233  C CE1 . PHE B 1 121 ? 113.648 110.630 157.037 1.00 47.62  ?  110 PHE B CE1 1 
ATOM   6234  C CE2 . PHE B 1 121 ? 113.386 112.685 158.224 1.00 47.62  ?  110 PHE B CE2 1 
ATOM   6235  C CZ  . PHE B 1 121 ? 112.829 111.580 157.613 1.00 47.62  ?  110 PHE B CZ  1 
ATOM   6236  N N   . PHE B 1 122 ? 117.139 114.951 156.383 1.00 47.32  ?  111 PHE B N   1 
ATOM   6237  C CA  . PHE B 1 122 ? 116.324 116.118 156.007 1.00 47.32  ?  111 PHE B CA  1 
ATOM   6238  C C   . PHE B 1 122 ? 116.593 116.783 154.629 1.00 47.32  ?  111 PHE B C   1 
ATOM   6239  O O   . PHE B 1 122 ? 115.637 117.091 153.932 1.00 47.32  ?  111 PHE B O   1 
ATOM   6240  C CB  . PHE B 1 122 ? 116.375 117.160 157.143 1.00 47.32  ?  111 PHE B CB  1 
ATOM   6241  C CG  . PHE B 1 122 ? 115.691 116.711 158.403 1.00 47.32  ?  111 PHE B CG  1 
ATOM   6242  C CD1 . PHE B 1 122 ? 114.316 116.801 158.527 1.00 47.32  ?  111 PHE B CD1 1 
ATOM   6243  C CD2 . PHE B 1 122 ? 116.419 116.201 159.461 1.00 47.32  ?  111 PHE B CD2 1 
ATOM   6244  C CE1 . PHE B 1 122 ? 113.680 116.389 159.681 1.00 47.32  ?  111 PHE B CE1 1 
ATOM   6245  C CE2 . PHE B 1 122 ? 115.791 115.785 160.619 1.00 47.32  ?  111 PHE B CE2 1 
ATOM   6246  C CZ  . PHE B 1 122 ? 114.420 115.881 160.730 1.00 47.32  ?  111 PHE B CZ  1 
ATOM   6247  N N   . PRO B 1 123 ? 117.868 117.010 154.235 1.00 45.99  ?  112 PRO B N   1 
ATOM   6248  C CA  . PRO B 1 123 ? 118.048 117.611 152.906 1.00 45.99  ?  112 PRO B CA  1 
ATOM   6249  C C   . PRO B 1 123 ? 117.624 116.708 151.763 1.00 45.99  ?  112 PRO B C   1 
ATOM   6250  O O   . PRO B 1 123 ? 117.148 117.212 150.744 1.00 45.99  ?  112 PRO B O   1 
ATOM   6251  C CB  . PRO B 1 123 ? 119.552 117.909 152.857 1.00 45.99  ?  112 PRO B CB  1 
ATOM   6252  C CG  . PRO B 1 123 ? 119.977 117.953 154.255 1.00 45.99  ?  112 PRO B CG  1 
ATOM   6253  C CD  . PRO B 1 123 ? 119.144 116.949 154.961 1.00 45.99  ?  112 PRO B CD  1 
ATOM   6254  N N   . ALA B 1 124 ? 117.783 115.392 151.898 1.00 47.00  ?  113 ALA B N   1 
ATOM   6255  C CA  . ALA B 1 124 ? 117.323 114.484 150.854 1.00 47.00  ?  113 ALA B CA  1 
ATOM   6256  C C   . ALA B 1 124 ? 115.814 114.559 150.688 1.00 47.00  ?  113 ALA B C   1 
ATOM   6257  O O   . ALA B 1 124 ? 115.302 114.557 149.563 1.00 47.00  ?  113 ALA B O   1 
ATOM   6258  C CB  . ALA B 1 124 ? 117.756 113.056 151.177 1.00 47.00  ?  113 ALA B CB  1 
ATOM   6259  N N   . ILE B 1 125 ? 115.085 114.659 151.801 1.00 48.55  ?  114 ILE B N   1 
ATOM   6260  C CA  . ILE B 1 125 ? 113.628 114.697 151.740 1.00 48.55  ?  114 ILE B CA  1 
ATOM   6261  C C   . ILE B 1 125 ? 113.149 116.017 151.153 1.00 48.55  ?  114 ILE B C   1 
ATOM   6262  O O   . ILE B 1 125 ? 112.149 116.057 150.427 1.00 48.55  ?  114 ILE B O   1 
ATOM   6263  C CB  . ILE B 1 125 ? 113.028 114.440 153.134 1.00 48.55  ?  114 ILE B CB  1 
ATOM   6264  C CG1 . ILE B 1 125 ? 113.346 113.021 153.591 1.00 48.55  ?  114 ILE B CG1 1 
ATOM   6265  C CG2 . ILE B 1 125 ? 111.530 114.639 153.120 1.00 48.55  ?  114 ILE B CG2 1 
ATOM   6266  C CD1 . ILE B 1 125 ? 112.591 111.963 152.832 1.00 48.55  ?  114 ILE B CD1 1 
ATOM   6267  N N   . ILE B 1 126 ? 113.840 117.120 151.446 1.00 47.64  ?  115 ILE B N   1 
ATOM   6268  C CA  . ILE B 1 126 ? 113.411 118.387 150.853 1.00 47.64  ?  115 ILE B CA  1 
ATOM   6269  C C   . ILE B 1 126 ? 113.783 118.444 149.373 1.00 47.64  ?  115 ILE B C   1 
ATOM   6270  O O   . ILE B 1 126 ? 113.009 118.938 148.540 1.00 47.64  ?  115 ILE B O   1 
ATOM   6271  C CB  . ILE B 1 126 ? 113.987 119.581 151.634 1.00 47.64  ?  115 ILE B CB  1 
ATOM   6272  C CG1 . ILE B 1 126 ? 112.991 120.059 152.688 1.00 47.64  ?  115 ILE B CG1 1 
ATOM   6273  C CG2 . ILE B 1 126 ? 114.290 120.731 150.700 1.00 47.64  ?  115 ILE B CG2 1 
ATOM   6274  C CD1 . ILE B 1 126 ? 112.795 119.096 153.823 1.00 47.64  ?  115 ILE B CD1 1 
ATOM   6275  N N   . TYR B 1 127 ? 114.958 117.925 149.016 1.00 46.50  ?  116 TYR B N   1 
ATOM   6276  C CA  . TYR B 1 127 ? 115.397 117.939 147.628 1.00 46.50  ?  116 TYR B CA  1 
ATOM   6277  C C   . TYR B 1 127 ? 114.566 117.010 146.759 1.00 46.50  ?  116 TYR B C   1 
ATOM   6278  O O   . TYR B 1 127 ? 114.466 117.229 145.549 1.00 46.50  ?  116 TYR B O   1 
ATOM   6279  C CB  . TYR B 1 127 ? 116.870 117.552 147.551 1.00 46.50  ?  116 TYR B CB  1 
ATOM   6280  C CG  . TYR B 1 127 ? 117.536 117.912 146.254 1.00 46.50  ?  116 TYR B CG  1 
ATOM   6281  C CD1 . TYR B 1 127 ? 118.177 119.127 146.101 1.00 46.50  ?  116 TYR B CD1 1 
ATOM   6282  C CD2 . TYR B 1 127 ? 117.541 117.029 145.188 1.00 46.50  ?  116 TYR B CD2 1 
ATOM   6283  C CE1 . TYR B 1 127 ? 118.791 119.457 144.925 1.00 46.50  ?  116 TYR B CE1 1 
ATOM   6284  C CE2 . TYR B 1 127 ? 118.152 117.351 144.010 1.00 46.50  ?  116 TYR B CE2 1 
ATOM   6285  C CZ  . TYR B 1 127 ? 118.771 118.567 143.885 1.00 46.50  ?  116 TYR B CZ  1 
ATOM   6286  O OH  . TYR B 1 127 ? 119.385 118.895 142.709 1.00 46.50  ?  116 TYR B OH  1 
ATOM   6287  N N   . LEU B 1 128 ? 113.985 115.962 147.345 1.00 50.04  ?  117 LEU B N   1 
ATOM   6288  C CA  . LEU B 1 128 ? 113.047 115.132 146.597 1.00 50.04  ?  117 LEU B CA  1 
ATOM   6289  C C   . LEU B 1 128 ? 111.925 115.962 145.999 1.00 50.04  ?  117 LEU B C   1 
ATOM   6290  O O   . LEU B 1 128 ? 111.457 115.672 144.893 1.00 50.04  ?  117 LEU B O   1 
ATOM   6291  C CB  . LEU B 1 128 ? 112.474 114.048 147.509 1.00 50.04  ?  117 LEU B CB  1 
ATOM   6292  C CG  . LEU B 1 128 ? 111.190 113.352 147.065 1.00 50.04  ?  117 LEU B CG  1 
ATOM   6293  C CD1 . LEU B 1 128 ? 111.497 112.116 146.257 1.00 50.04  ?  117 LEU B CD1 1 
ATOM   6294  C CD2 . LEU B 1 128 ? 110.340 113.007 148.266 1.00 50.04  ?  117 LEU B CD2 1 
ATOM   6295  N N   . PHE B 1 129 ? 111.495 117.006 146.701 1.00 51.67  ?  118 PHE B N   1 
ATOM   6296  C CA  . PHE B 1 129 ? 110.407 117.860 146.246 1.00 51.67  ?  118 PHE B CA  1 
ATOM   6297  C C   . PHE B 1 129 ? 110.893 119.044 145.423 1.00 51.67  ?  118 PHE B C   1 
ATOM   6298  O O   . PHE B 1 129 ? 110.309 119.349 144.379 1.00 51.67  ?  118 PHE B O   1 
ATOM   6299  C CB  . PHE B 1 129 ? 109.610 118.373 147.445 1.00 51.67  ?  118 PHE B CB  1 
ATOM   6300  C CG  . PHE B 1 129 ? 108.788 117.322 148.117 1.00 51.67  ?  118 PHE B CG  1 
ATOM   6301  C CD1 . PHE B 1 129 ? 107.602 116.891 147.560 1.00 51.67  ?  118 PHE B CD1 1 
ATOM   6302  C CD2 . PHE B 1 129 ? 109.198 116.767 149.313 1.00 51.67  ?  118 PHE B CD2 1 
ATOM   6303  C CE1 . PHE B 1 129 ? 106.846 115.927 148.177 1.00 51.67  ?  118 PHE B CE1 1 
ATOM   6304  C CE2 . PHE B 1 129 ? 108.445 115.802 149.935 1.00 51.67  ?  118 PHE B CE2 1 
ATOM   6305  C CZ  . PHE B 1 129 ? 107.268 115.382 149.366 1.00 51.67  ?  118 PHE B CZ  1 
ATOM   6306  N N   . PHE B 1 130 ? 111.930 119.724 145.884 1.00 51.87  ?  119 PHE B N   1 
ATOM   6307  C CA  . PHE B 1 130 ? 112.353 120.937 145.206 1.00 51.87  ?  119 PHE B CA  1 
ATOM   6308  C C   . PHE B 1 130 ? 113.582 120.777 144.332 1.00 51.87  ?  119 PHE B C   1 
ATOM   6309  O O   . PHE B 1 130 ? 113.997 121.724 143.675 1.00 51.87  ?  119 PHE B O   1 
ATOM   6310  C CB  . PHE B 1 130 ? 112.584 122.030 146.252 1.00 51.87  ?  119 PHE B CB  1 
ATOM   6311  C CG  . PHE B 1 130 ? 111.409 122.262 147.153 1.00 51.87  ?  119 PHE B CG  1 
ATOM   6312  C CD1 . PHE B 1 130 ? 110.441 123.192 146.824 1.00 51.87  ?  119 PHE B CD1 1 
ATOM   6313  C CD2 . PHE B 1 130 ? 111.271 121.546 148.329 1.00 51.87  ?  119 PHE B CD2 1 
ATOM   6314  C CE1 . PHE B 1 130 ? 109.358 123.408 147.650 1.00 51.87  ?  119 PHE B CE1 1 
ATOM   6315  C CE2 . PHE B 1 130 ? 110.190 121.754 149.159 1.00 51.87  ?  119 PHE B CE2 1 
ATOM   6316  C CZ  . PHE B 1 130 ? 109.231 122.687 148.821 1.00 51.87  ?  119 PHE B CZ  1 
ATOM   6317  N N   . GLY B 1 131 ? 114.158 119.588 144.307 1.00 49.80  ?  120 GLY B N   1 
ATOM   6318  C CA  . GLY B 1 131 ? 115.367 119.378 143.540 1.00 49.80  ?  120 GLY B CA  1 
ATOM   6319  C C   . GLY B 1 131 ? 115.165 119.073 142.079 1.00 49.80  ?  120 GLY B C   1 
ATOM   6320  O O   . GLY B 1 131 ? 114.139 118.534 141.688 1.00 49.80  ?  120 GLY B O   1 
ATOM   6321  N N   . THR B 1 132 ? 116.152 119.410 141.264 1.00 50.55  ?  121 THR B N   1 
ATOM   6322  C CA  . THR B 1 132 ? 116.065 119.147 139.829 1.00 50.55  ?  121 THR B CA  1 
ATOM   6323  C C   . THR B 1 132 ? 116.984 118.013 139.382 1.00 50.55  ?  121 THR B C   1 
ATOM   6324  O O   . THR B 1 132 ? 116.844 117.513 138.274 1.00 50.55  ?  121 THR B O   1 
ATOM   6325  C CB  . THR B 1 132 ? 116.364 120.413 138.990 1.00 50.55  ?  121 THR B CB  1 
ATOM   6326  O OG1 . THR B 1 132 ? 117.723 120.816 139.185 1.00 50.55  ?  121 THR B OG1 1 
ATOM   6327  C CG2 . THR B 1 132 ? 115.440 121.546 139.394 1.00 50.55  ?  121 THR B CG2 1 
ATOM   6328  N N   . SER B 1 133 ? 117.916 117.601 140.230 1.00 49.72  ?  122 SER B N   1 
ATOM   6329  C CA  . SER B 1 133 ? 118.770 116.470 139.885 1.00 49.72  ?  122 SER B CA  1 
ATOM   6330  C C   . SER B 1 133 ? 118.017 115.182 140.111 1.00 49.72  ?  122 SER B C   1 
ATOM   6331  O O   . SER B 1 133 ? 117.097 115.130 140.914 1.00 49.72  ?  122 SER B O   1 
ATOM   6332  C CB  . SER B 1 133 ? 120.063 116.473 140.693 1.00 49.72  ?  122 SER B CB  1 
ATOM   6333  O OG  . SER B 1 133 ? 120.842 115.327 140.405 1.00 49.72  ?  122 SER B OG  1 
ATOM   6334  N N   . ARG B 1 134 ? 118.387 114.146 139.383 1.00 51.73  ?  123 ARG B N   1 
ATOM   6335  C CA  . ARG B 1 134 ? 117.722 112.867 139.524 1.00 51.73  ?  123 ARG B CA  1 
ATOM   6336  C C   . ARG B 1 134 ? 118.685 111.813 139.998 1.00 51.73  ?  123 ARG B C   1 
ATOM   6337  O O   . ARG B 1 134 ? 118.315 110.657 140.145 1.00 51.73  ?  123 ARG B O   1 
ATOM   6338  C CB  . ARG B 1 134 ? 117.138 112.452 138.181 1.00 51.73  ?  123 ARG B CB  1 
ATOM   6339  C CG  . ARG B 1 134 ? 116.257 113.496 137.526 1.00 51.73  ?  123 ARG B CG  1 
ATOM   6340  C CD  . ARG B 1 134 ? 116.047 113.140 136.069 1.00 51.73  ?  123 ARG B CD  1 
ATOM   6341  N NE  . ARG B 1 134 ? 115.916 111.698 135.907 1.00 51.73  ?  123 ARG B NE  1 
ATOM   6342  C CZ  . ARG B 1 134 ? 115.815 111.080 134.737 1.00 51.73  ?  123 ARG B CZ  1 
ATOM   6343  N NH1 . ARG B 1 134 ? 115.701 109.759 134.694 1.00 51.73  1  123 ARG B NH1 1 
ATOM   6344  N NH2 . ARG B 1 134 ? 115.826 111.780 133.611 1.00 51.73  ?  123 ARG B NH2 1 
ATOM   6345  N N   . HIS B 1 135 ? 119.924 112.196 140.254 1.00 49.98  ?  124 HIS B N   1 
ATOM   6346  C CA  . HIS B 1 135 ? 120.925 111.200 140.595 1.00 49.98  ?  124 HIS B CA  1 
ATOM   6347  C C   . HIS B 1 135 ? 121.784 111.536 141.793 1.00 49.98  ?  124 HIS B C   1 
ATOM   6348  O O   . HIS B 1 135 ? 122.384 110.648 142.386 1.00 49.98  ?  124 HIS B O   1 
ATOM   6349  C CB  . HIS B 1 135 ? 121.830 110.982 139.380 1.00 49.98  ?  124 HIS B CB  1 
ATOM   6350  C CG  . HIS B 1 135 ? 121.105 110.512 138.161 1.00 49.98  ?  124 HIS B CG  1 
ATOM   6351  N ND1 . HIS B 1 135 ? 120.570 111.379 137.234 1.00 49.98  ?  124 HIS B ND1 1 
ATOM   6352  C CD2 . HIS B 1 135 ? 120.826 109.265 137.714 1.00 49.98  ?  124 HIS B CD2 1 
ATOM   6353  C CE1 . HIS B 1 135 ? 119.990 110.688 136.271 1.00 49.98  ?  124 HIS B CE1 1 
ATOM   6354  N NE2 . HIS B 1 135 ? 120.131 109.402 136.537 1.00 49.98  ?  124 HIS B NE2 1 
ATOM   6355  N N   . ILE B 1 136 ? 121.863 112.807 142.148 1.00 47.58  ?  125 ILE B N   1 
ATOM   6356  C CA  . ILE B 1 136 ? 122.761 113.186 143.228 1.00 47.58  ?  125 ILE B CA  1 
ATOM   6357  C C   . ILE B 1 136 ? 122.208 112.800 144.573 1.00 47.58  ?  125 ILE B C   1 
ATOM   6358  O O   . ILE B 1 136 ? 121.024 112.944 144.846 1.00 47.58  ?  125 ILE B O   1 
ATOM   6359  C CB  . ILE B 1 136 ? 123.087 114.693 143.243 1.00 47.58  ?  125 ILE B CB  1 
ATOM   6360  C CG1 . ILE B 1 136 ? 121.847 115.514 143.618 1.00 47.58  ?  125 ILE B CG1 1 
ATOM   6361  C CG2 . ILE B 1 136 ? 123.668 115.124 141.903 1.00 47.58  ?  125 ILE B CG2 1 
ATOM   6362  C CD1 . ILE B 1 136 ? 122.149 116.953 143.963 1.00 47.58  ?  125 ILE B CD1 1 
ATOM   6363  N N   . SER B 1 137 ? 123.070 112.264 145.410 1.00 47.52  ?  126 SER B N   1 
ATOM   6364  C CA  . SER B 1 137 ? 122.622 111.976 146.763 1.00 47.52  ?  126 SER B CA  1 
ATOM   6365  C C   . SER B 1 137 ? 122.858 113.219 147.606 1.00 47.52  ?  126 SER B C   1 
ATOM   6366  O O   . SER B 1 137 ? 123.947 113.801 147.561 1.00 47.52  ?  126 SER B O   1 
ATOM   6367  C CB  . SER B 1 137 ? 123.362 110.776 147.348 1.00 47.52  ?  126 SER B CB  1 
ATOM   6368  O OG  . SER B 1 137 ? 122.565 110.106 148.304 1.00 47.52  ?  126 SER B OG  1 
ATOM   6369  N N   . VAL B 1 138 ? 121.850 113.624 148.366 1.00 46.50  ?  127 VAL B N   1 
ATOM   6370  C CA  . VAL B 1 138 ? 121.898 114.875 149.112 1.00 46.50  ?  127 VAL B CA  1 
ATOM   6371  C C   . VAL B 1 138 ? 122.192 114.576 150.575 1.00 46.50  ?  127 VAL B C   1 
ATOM   6372  O O   . VAL B 1 138 ? 121.534 113.734 151.196 1.00 46.50  ?  127 VAL B O   1 
ATOM   6373  C CB  . VAL B 1 138 ? 120.587 115.658 148.954 1.00 46.50  ?  127 VAL B CB  1 
ATOM   6374  C CG1 . VAL B 1 138 ? 120.774 117.091 149.390 1.00 46.50  ?  127 VAL B CG1 1 
ATOM   6375  C CG2 . VAL B 1 138 ? 120.118 115.603 147.518 1.00 46.50  ?  127 VAL B CG2 1 
ATOM   6376  N N   . GLY B 1 139 ? 123.187 115.265 151.122 1.00 46.68  ?  128 GLY B N   1 
ATOM   6377  C CA  . GLY B 1 139 ? 123.642 115.030 152.468 1.00 46.68  ?  128 GLY B CA  1 
ATOM   6378  C C   . GLY B 1 139 ? 125.009 115.642 152.677 1.00 46.68  ?  128 GLY B C   1 
ATOM   6379  O O   . GLY B 1 139 ? 125.500 116.403 151.841 1.00 46.68  ?  128 GLY B O   1 
ATOM   6380  N N   . PRO B 1 140 ? 125.658 115.310 153.785 1.00 45.54  ?  129 PRO B N   1 
ATOM   6381  C CA  . PRO B 1 140 ? 126.962 115.896 154.090 1.00 45.54  ?  129 PRO B CA  1 
ATOM   6382  C C   . PRO B 1 140 ? 128.092 115.254 153.294 1.00 45.54  ?  129 PRO B C   1 
ATOM   6383  O O   . PRO B 1 140 ? 128.023 114.097 152.879 1.00 45.54  ?  129 PRO B O   1 
ATOM   6384  C CB  . PRO B 1 140 ? 127.118 115.606 155.588 1.00 45.54  ?  129 PRO B CB  1 
ATOM   6385  C CG  . PRO B 1 140 ? 126.384 114.335 155.782 1.00 45.54  ?  129 PRO B CG  1 
ATOM   6386  C CD  . PRO B 1 140 ? 125.229 114.356 154.822 1.00 45.54  ?  129 PRO B CD  1 
ATOM   6387  N N   . PHE B 1 141 ? 129.138 116.038 153.079 1.00 44.53  ?  130 PHE B N   1 
ATOM   6388  C CA  . PHE B 1 141 ? 130.372 115.553 152.484 1.00 44.53  ?  130 PHE B CA  1 
ATOM   6389  C C   . PHE B 1 141 ? 131.537 116.099 153.293 1.00 44.53  ?  130 PHE B C   1 
ATOM   6390  O O   . PHE B 1 141 ? 131.377 117.077 154.030 1.00 44.53  ?  130 PHE B O   1 
ATOM   6391  C CB  . PHE B 1 141 ? 130.482 115.930 150.998 1.00 44.53  ?  130 PHE B CB  1 
ATOM   6392  C CG  . PHE B 1 141 ? 130.360 117.393 150.704 1.00 44.53  ?  130 PHE B CG  1 
ATOM   6393  C CD1 . PHE B 1 141 ? 131.483 118.151 150.448 1.00 44.53  ?  130 PHE B CD1 1 
ATOM   6394  C CD2 . PHE B 1 141 ? 129.124 117.997 150.621 1.00 44.53  ?  130 PHE B CD2 1 
ATOM   6395  C CE1 . PHE B 1 141 ? 131.377 119.484 150.154 1.00 44.53  ?  130 PHE B CE1 1 
ATOM   6396  C CE2 . PHE B 1 141 ? 129.014 119.332 150.329 1.00 44.53  ?  130 PHE B CE2 1 
ATOM   6397  C CZ  . PHE B 1 141 ? 130.143 120.075 150.091 1.00 44.53  ?  130 PHE B CZ  1 
ATOM   6398  N N   . PRO B 1 142 ? 132.717 115.468 153.204 1.00 44.24  ?  131 PRO B N   1 
ATOM   6399  C CA  . PRO B 1 142 ? 133.790 115.789 154.165 1.00 44.24  ?  131 PRO B CA  1 
ATOM   6400  C C   . PRO B 1 142 ? 134.212 117.248 154.189 1.00 44.24  ?  131 PRO B C   1 
ATOM   6401  O O   . PRO B 1 142 ? 134.418 117.805 155.273 1.00 44.24  ?  131 PRO B O   1 
ATOM   6402  C CB  . PRO B 1 142 ? 134.941 114.887 153.710 1.00 44.24  ?  131 PRO B CB  1 
ATOM   6403  C CG  . PRO B 1 142 ? 134.304 113.786 152.993 1.00 44.24  ?  131 PRO B CG  1 
ATOM   6404  C CD  . PRO B 1 142 ? 133.106 114.358 152.318 1.00 44.24  ?  131 PRO B CD  1 
ATOM   6405  N N   . ILE B 1 143 ? 134.366 117.880 153.027 1.00 45.27  ?  132 ILE B N   1 
ATOM   6406  C CA  . ILE B 1 143 ? 134.841 119.259 152.993 1.00 45.27  ?  132 ILE B CA  1 
ATOM   6407  C C   . ILE B 1 143 ? 133.856 120.183 153.695 1.00 45.27  ?  132 ILE B C   1 
ATOM   6408  O O   . ILE B 1 143 ? 134.252 121.056 154.478 1.00 45.27  ?  132 ILE B O   1 
ATOM   6409  C CB  . ILE B 1 143 ? 135.094 119.704 151.542 1.00 45.27  ?  132 ILE B CB  1 
ATOM   6410  C CG1 . ILE B 1 143 ? 136.082 118.759 150.861 1.00 45.27  ?  132 ILE B CG1 1 
ATOM   6411  C CG2 . ILE B 1 143 ? 135.614 121.125 151.507 1.00 45.27  ?  132 ILE B CG2 1 
ATOM   6412  C CD1 . ILE B 1 143 ? 136.301 119.075 149.407 1.00 45.27  ?  132 ILE B CD1 1 
ATOM   6413  N N   . LEU B 1 144 ? 132.561 119.999 153.447 1.00 43.68  ?  133 LEU B N   1 
ATOM   6414  C CA  . LEU B 1 144 ? 131.585 120.875 154.081 1.00 43.68  ?  133 LEU B CA  1 
ATOM   6415  C C   . LEU B 1 144 ? 131.449 120.585 155.564 1.00 43.68  ?  133 LEU B C   1 
ATOM   6416  O O   . LEU B 1 144 ? 131.216 121.508 156.345 1.00 43.68  ?  133 LEU B O   1 
ATOM   6417  C CB  . LEU B 1 144 ? 130.225 120.752 153.407 1.00 43.68  ?  133 LEU B CB  1 
ATOM   6418  C CG  . LEU B 1 144 ? 129.416 122.049 153.403 1.00 43.68  ?  133 LEU B CG  1 
ATOM   6419  C CD1 . LEU B 1 144 ? 130.154 123.121 152.628 1.00 43.68  ?  133 LEU B CD1 1 
ATOM   6420  C CD2 . LEU B 1 144 ? 128.041 121.821 152.825 1.00 43.68  ?  133 LEU B CD2 1 
ATOM   6421  N N   . SER B 1 145 ? 131.576 119.324 155.975 1.00 45.37  ?  134 SER B N   1 
ATOM   6422  C CA  . SER B 1 145 ? 131.543 119.024 157.399 1.00 45.37  ?  134 SER B CA  1 
ATOM   6423  C C   . SER B 1 145 ? 132.723 119.660 158.113 1.00 45.37  ?  134 SER B C   1 
ATOM   6424  O O   . SER B 1 145 ? 132.584 120.154 159.235 1.00 45.37  ?  134 SER B O   1 
ATOM   6425  C CB  . SER B 1 145 ? 131.528 117.517 157.622 1.00 45.37  ?  134 SER B CB  1 
ATOM   6426  O OG  . SER B 1 145 ? 130.709 116.883 156.662 1.00 45.37  ?  134 SER B OG  1 
ATOM   6427  N N   . MET B 1 146 ? 133.886 119.687 157.463 1.00 46.12  ?  135 MET B N   1 
ATOM   6428  C CA  . MET B 1 146 ? 135.036 120.362 158.052 1.00 46.12  ?  135 MET B CA  1 
ATOM   6429  C C   . MET B 1 146 ? 134.817 121.866 158.131 1.00 46.12  ?  135 MET B C   1 
ATOM   6430  O O   . MET B 1 146 ? 135.141 122.495 159.144 1.00 46.12  ?  135 MET B O   1 
ATOM   6431  C CB  . MET B 1 146 ? 136.292 120.039 157.250 1.00 46.12  ?  135 MET B CB  1 
ATOM   6432  C CG  . MET B 1 146 ? 136.978 118.767 157.693 1.00 46.12  ?  135 MET B CG  1 
ATOM   6433  S SD  . MET B 1 146 ? 138.757 118.905 157.557 1.00 46.12  ?  135 MET B SD  1 
ATOM   6434  C CE  . MET B 1 146 ? 138.977 120.625 157.985 1.00 46.12  ?  135 MET B CE  1 
ATOM   6435  N N   . MET B 1 147 ? 134.276 122.466 157.067 1.00 45.06  ?  136 MET B N   1 
ATOM   6436  C CA  . MET B 1 147 ? 133.976 123.894 157.094 1.00 45.06  ?  136 MET B CA  1 
ATOM   6437  C C   . MET B 1 147 ? 132.971 124.235 158.191 1.00 45.06  ?  136 MET B C   1 
ATOM   6438  O O   . MET B 1 147 ? 133.120 125.242 158.888 1.00 45.06  ?  136 MET B O   1 
ATOM   6439  C CB  . MET B 1 147 ? 133.452 124.342 155.732 1.00 45.06  ?  136 MET B CB  1 
ATOM   6440  C CG  . MET B 1 147 ? 134.452 124.213 154.606 1.00 45.06  ?  136 MET B CG  1 
ATOM   6441  S SD  . MET B 1 147 ? 133.915 125.064 153.120 1.00 45.06  ?  136 MET B SD  1 
ATOM   6442  C CE  . MET B 1 147 ? 134.171 126.760 153.604 1.00 45.06  ?  136 MET B CE  1 
ATOM   6443  N N   . VAL B 1 148 ? 131.947 123.398 158.365 1.00 45.98  ?  137 VAL B N   1 
ATOM   6444  C CA  . VAL B 1 148 ? 130.952 123.629 159.406 1.00 45.98  ?  137 VAL B CA  1 
ATOM   6445  C C   . VAL B 1 148 ? 131.575 123.477 160.787 1.00 45.98  ?  137 VAL B C   1 
ATOM   6446  O O   . VAL B 1 148 ? 131.291 124.260 161.698 1.00 45.98  ?  137 VAL B O   1 
ATOM   6447  C CB  . VAL B 1 148 ? 129.750 122.684 159.220 1.00 45.98  ?  137 VAL B CB  1 
ATOM   6448  C CG1 . VAL B 1 148 ? 128.817 122.760 160.410 1.00 45.98  ?  137 VAL B CG1 1 
ATOM   6449  C CG2 . VAL B 1 148 ? 129.000 123.019 157.952 1.00 45.98  ?  137 VAL B CG2 1 
ATOM   6450  N N   . GLY B 1 149 ? 132.429 122.470 160.970 1.00 47.19  ?  138 GLY B N   1 
ATOM   6451  C CA  . GLY B 1 149 ? 133.097 122.311 162.249 1.00 47.19  ?  138 GLY B CA  1 
ATOM   6452  C C   . GLY B 1 149 ? 133.970 123.496 162.600 1.00 47.19  ?  138 GLY B C   1 
ATOM   6453  O O   . GLY B 1 149 ? 133.974 123.960 163.740 1.00 47.19  ?  138 GLY B O   1 
ATOM   6454  N N   . LEU B 1 150 ? 134.748 123.988 161.658 1.00 47.92  ?  139 LEU B N   1 
ATOM   6455  C CA  . LEU B 1 150 ? 135.593 125.122 161.940 1.00 47.92  ?  139 LEU B CA  1 
ATOM   6456  C C   . LEU B 1 150 ? 134.748 126.315 162.361 1.00 47.92  ?  139 LEU B C   1 
ATOM   6457  O O   . LEU B 1 150 ? 135.110 127.042 163.282 1.00 47.92  ?  139 LEU B O   1 
ATOM   6458  C CB  . LEU B 1 150 ? 136.456 125.446 160.724 1.00 47.92  ?  139 LEU B CB  1 
ATOM   6459  C CG  . LEU B 1 150 ? 137.512 124.386 160.411 1.00 47.92  ?  139 LEU B CG  1 
ATOM   6460  C CD1 . LEU B 1 150 ? 138.022 124.508 158.986 1.00 47.92  ?  139 LEU B CD1 1 
ATOM   6461  C CD2 . LEU B 1 150 ? 138.652 124.438 161.416 1.00 47.92  ?  139 LEU B CD2 1 
ATOM   6462  N N   . ALA B 1 151 ? 133.607 126.497 161.715 1.00 49.24  ?  140 ALA B N   1 
ATOM   6463  C CA  . ALA B 1 151 ? 132.735 127.615 162.039 1.00 49.24  ?  140 ALA B CA  1 
ATOM   6464  C C   . ALA B 1 151 ? 132.228 127.551 163.472 1.00 49.24  ?  140 ALA B C   1 
ATOM   6465  O O   . ALA B 1 151 ? 132.224 128.556 164.171 1.00 49.24  ?  140 ALA B O   1 
ATOM   6466  C CB  . ALA B 1 151 ? 131.572 127.671 161.064 1.00 49.24  ?  140 ALA B CB  1 
ATOM   6467  N N   . VAL B 1 152 ? 131.815 126.374 163.912 1.00 51.58  ?  141 VAL B N   1 
ATOM   6468  C CA  . VAL B 1 152 ? 131.277 126.226 165.260 1.00 51.58  ?  141 VAL B CA  1 
ATOM   6469  C C   . VAL B 1 152 ? 132.341 126.427 166.333 1.00 51.58  ?  141 VAL B C   1 
ATOM   6470  O O   . VAL B 1 152 ? 132.056 126.998 167.380 1.00 51.58  ?  141 VAL B O   1 
ATOM   6471  C CB  . VAL B 1 152 ? 130.554 124.872 165.447 1.00 51.58  ?  141 VAL B CB  1 
ATOM   6472  C CG1 . VAL B 1 152 ? 129.366 124.790 164.507 1.00 51.58  ?  141 VAL B CG1 1 
ATOM   6473  C CG2 . VAL B 1 152 ? 131.488 123.721 165.178 1.00 51.58  ?  141 VAL B CG2 1 
ATOM   6474  N N   . SER B 1 153 ? 133.559 125.973 166.078 1.00 53.25  ?  142 SER B N   1 
ATOM   6475  C CA  . SER B 1 153 ? 134.639 126.156 167.030 1.00 53.25  ?  142 SER B CA  1 
ATOM   6476  C C   . SER B 1 153 ? 134.908 127.645 167.185 1.00 53.25  ?  142 SER B C   1 
ATOM   6477  O O   . SER B 1 153 ? 135.138 128.133 168.290 1.00 53.25  ?  142 SER B O   1 
ATOM   6478  C CB  . SER B 1 153 ? 135.886 125.394 166.583 1.00 53.25  ?  142 SER B CB  1 
ATOM   6479  O OG  . SER B 1 153 ? 135.658 123.998 166.586 1.00 53.25  ?  142 SER B OG  1 
ATOM   6480  N N   . GLY B 1 154 ? 134.855 128.382 166.084 1.00 55.44  ?  143 GLY B N   1 
ATOM   6481  C CA  . GLY B 1 154 ? 135.034 129.817 166.150 1.00 55.44  ?  143 GLY B CA  1 
ATOM   6482  C C   . GLY B 1 154 ? 133.894 130.498 166.868 1.00 55.44  ?  143 GLY B C   1 
ATOM   6483  O O   . GLY B 1 154 ? 134.113 131.408 167.658 1.00 55.44  ?  143 GLY B O   1 
ATOM   6484  N N   . ALA B 1 155 ? 132.670 130.056 166.609 1.00 56.47  ?  144 ALA B N   1 
ATOM   6485  C CA  . ALA B 1 155 ? 131.508 130.636 167.260 1.00 56.47  ?  144 ALA B CA  1 
ATOM   6486  C C   . ALA B 1 155 ? 131.525 130.430 168.775 1.00 56.47  ?  144 ALA B C   1 
ATOM   6487  O O   . ALA B 1 155 ? 131.195 131.341 169.525 1.00 56.47  ?  144 ALA B O   1 
ATOM   6488  C CB  . ALA B 1 155 ? 130.233 130.065 166.665 1.00 56.47  ?  144 ALA B CB  1 
ATOM   6489  N N   . VAL B 1 156 ? 131.905 129.239 169.225 1.00 59.54  ?  145 VAL B N   1 
ATOM   6490  C CA  . VAL B 1 156 ? 131.944 128.971 170.656 1.00 59.54  ?  145 VAL B CA  1 
ATOM   6491  C C   . VAL B 1 156 ? 133.010 129.843 171.308 1.00 59.54  ?  145 VAL B C   1 
ATOM   6492  O O   . VAL B 1 156 ? 132.830 130.311 172.427 1.00 59.54  ?  145 VAL B O   1 
ATOM   6493  C CB  . VAL B 1 156 ? 132.178 127.480 170.979 1.00 59.54  ?  145 VAL B CB  1 
ATOM   6494  C CG1 . VAL B 1 156 ? 131.063 126.629 170.388 1.00 59.54  ?  145 VAL B CG1 1 
ATOM   6495  C CG2 . VAL B 1 156 ? 133.534 127.018 170.479 1.00 59.54  ?  145 VAL B CG2 1 
ATOM   6496  N N   . SER B 1 157 ? 134.114 130.072 170.611 1.00 60.43  ?  146 SER B N   1 
ATOM   6497  C CA  . SER B 1 157 ? 135.150 130.946 171.134 1.00 60.43  ?  146 SER B CA  1 
ATOM   6498  C C   . SER B 1 157 ? 134.679 132.389 171.216 1.00 60.43  ?  146 SER B C   1 
ATOM   6499  O O   . SER B 1 157 ? 135.037 133.098 172.150 1.00 60.43  ?  146 SER B O   1 
ATOM   6500  C CB  . SER B 1 157 ? 136.395 130.865 170.255 1.00 60.43  ?  146 SER B CB  1 
ATOM   6501  O OG  . SER B 1 157 ? 136.886 129.539 170.191 1.00 60.43  ?  146 SER B OG  1 
ATOM   6502  N N   . LYS B 1 158 ? 133.877 132.827 170.254 1.00 63.86  ?  147 LYS B N   1 
ATOM   6503  C CA  . LYS B 1 158 ? 133.440 134.220 170.214 1.00 63.86  ?  147 LYS B CA  1 
ATOM   6504  C C   . LYS B 1 158 ? 132.086 134.466 170.861 1.00 63.86  ?  147 LYS B C   1 
ATOM   6505  O O   . LYS B 1 158 ? 131.285 135.228 170.328 1.00 63.86  ?  147 LYS B O   1 
ATOM   6506  C CB  . LYS B 1 158 ? 133.366 134.693 168.763 1.00 63.86  ?  147 LYS B CB  1 
ATOM   6507  C CG  . LYS B 1 158 ? 134.613 134.438 167.944 1.00 63.86  ?  147 LYS B CG  1 
ATOM   6508  C CD  . LYS B 1 158 ? 134.339 134.709 166.476 1.00 63.86  ?  147 LYS B CD  1 
ATOM   6509  C CE  . LYS B 1 158 ? 135.513 134.293 165.606 1.00 63.86  ?  147 LYS B CE  1 
ATOM   6510  N NZ  . LYS B 1 158 ? 135.218 134.490 164.161 1.00 63.86  1  147 LYS B NZ  1 
ATOM   6511  N N   . ALA B 1 159 ? 131.818 133.842 171.998 1.00 69.91  ?  148 ALA B N   1 
ATOM   6512  C CA  . ALA B 1 159 ? 130.505 133.982 172.620 1.00 69.91  ?  148 ALA B CA  1 
ATOM   6513  C C   . ALA B 1 159 ? 130.526 134.666 173.997 1.00 69.91  ?  148 ALA B C   1 
ATOM   6514  O O   . ALA B 1 159 ? 131.115 134.137 174.936 1.00 69.91  ?  148 ALA B O   1 
ATOM   6515  C CB  . ALA B 1 159 ? 129.844 132.616 172.716 1.00 69.91  ?  148 ALA B CB  1 
ATOM   6516  N N   . VAL B 1 160 ? 129.883 135.830 174.123 1.00 77.63  ?  149 VAL B N   1 
ATOM   6517  C CA  . VAL B 1 160 ? 129.819 136.539 175.396 1.00 77.63  ?  149 VAL B CA  1 
ATOM   6518  C C   . VAL B 1 160 ? 128.990 135.715 176.375 1.00 77.63  ?  149 VAL B C   1 
ATOM   6519  O O   . VAL B 1 160 ? 127.802 135.464 176.129 1.00 77.63  ?  149 VAL B O   1 
ATOM   6520  C CB  . VAL B 1 160 ? 129.252 137.956 175.213 1.00 77.63  ?  149 VAL B CB  1 
ATOM   6521  C CG1 . VAL B 1 160 ? 130.322 138.873 174.647 1.00 77.63  ?  149 VAL B CG1 1 
ATOM   6522  C CG2 . VAL B 1 160 ? 128.047 137.937 174.289 1.00 77.63  ?  149 VAL B CG2 1 
ATOM   6523  N N   . PRO B 1 161 ? 129.575 135.261 177.492 1.00 80.98  ?  150 PRO B N   1 
ATOM   6524  C CA  . PRO B 1 161 ? 128.885 134.398 178.456 1.00 80.98  ?  150 PRO B CA  1 
ATOM   6525  C C   . PRO B 1 161 ? 127.836 135.141 179.275 1.00 80.98  ?  150 PRO B C   1 
ATOM   6526  O O   . PRO B 1 161 ? 127.131 134.500 180.054 1.00 80.98  ?  150 PRO B O   1 
ATOM   6527  C CB  . PRO B 1 161 ? 130.020 133.902 179.350 1.00 80.98  ?  150 PRO B CB  1 
ATOM   6528  C CG  . PRO B 1 161 ? 131.029 134.990 179.293 1.00 80.98  ?  150 PRO B CG  1 
ATOM   6529  C CD  . PRO B 1 161 ? 130.962 135.542 177.899 1.00 80.98  ?  150 PRO B CD  1 
ATOM   6530  N N   . LEU B 1 180 ? 128.747 117.446 178.526 1.00 79.78  ?  169 LEU B N   1 
ATOM   6531  C CA  . LEU B 1 180 ? 127.544 117.375 177.726 1.00 79.78  ?  169 LEU B CA  1 
ATOM   6532  C C   . LEU B 1 180 ? 127.208 118.790 177.342 1.00 79.78  ?  169 LEU B C   1 
ATOM   6533  O O   . LEU B 1 180 ? 126.616 119.026 176.295 1.00 79.78  ?  169 LEU B O   1 
ATOM   6534  C CB  . LEU B 1 180 ? 126.406 116.747 178.515 1.00 79.78  ?  169 LEU B CB  1 
ATOM   6535  N N   . ASP B 1 181 ? 127.592 119.738 178.185 1.00 77.79  ?  170 ASP B N   1 
ATOM   6536  C CA  . ASP B 1 181 ? 127.354 121.139 177.888 1.00 77.79  ?  170 ASP B CA  1 
ATOM   6537  C C   . ASP B 1 181 ? 128.122 121.527 176.651 1.00 77.79  ?  170 ASP B C   1 
ATOM   6538  O O   . ASP B 1 181 ? 127.614 122.248 175.799 1.00 77.79  ?  170 ASP B O   1 
ATOM   6539  C CB  . ASP B 1 181 ? 127.793 122.000 179.067 1.00 77.79  ?  170 ASP B CB  1 
ATOM   6540  C CG  . ASP B 1 181 ? 126.989 121.721 180.318 1.00 77.79  ?  170 ASP B CG  1 
ATOM   6541  O OD1 . ASP B 1 181 ? 126.008 120.952 180.235 1.00 77.79  ?  170 ASP B OD1 1 
ATOM   6542  O OD2 . ASP B 1 181 ? 127.335 122.272 181.384 1.00 77.79  -1 170 ASP B OD2 1 
ATOM   6543  N N   . ASP B 1 182 ? 129.352 121.046 176.547 1.00 76.16  ?  171 ASP B N   1 
ATOM   6544  C CA  . ASP B 1 182 ? 130.161 121.328 175.374 1.00 76.16  ?  171 ASP B CA  1 
ATOM   6545  C C   . ASP B 1 182 ? 129.502 120.732 174.146 1.00 76.16  ?  171 ASP B C   1 
ATOM   6546  O O   . ASP B 1 182 ? 129.419 121.380 173.107 1.00 76.16  ?  171 ASP B O   1 
ATOM   6547  C CB  . ASP B 1 182 ? 131.561 120.759 175.559 1.00 76.16  ?  171 ASP B CB  1 
ATOM   6548  C CG  . ASP B 1 182 ? 132.262 121.328 176.774 1.00 76.16  ?  171 ASP B CG  1 
ATOM   6549  O OD1 . ASP B 1 182 ? 133.358 120.837 177.116 1.00 76.16  ?  171 ASP B OD1 1 
ATOM   6550  O OD2 . ASP B 1 182 ? 131.714 122.267 177.388 1.00 76.16  -1 171 ASP B OD2 1 
ATOM   6551  N N   . GLU B 1 183 ? 129.017 119.505 174.268 1.00 72.80  ?  172 GLU B N   1 
ATOM   6552  C CA  . GLU B 1 183 ? 128.329 118.867 173.161 1.00 72.80  ?  172 GLU B CA  1 
ATOM   6553  C C   . GLU B 1 183 ? 127.090 119.655 172.806 1.00 72.80  ?  172 GLU B C   1 
ATOM   6554  O O   . GLU B 1 183 ? 126.822 119.894 171.637 1.00 72.80  ?  172 GLU B O   1 
ATOM   6555  C CB  . GLU B 1 183 ? 127.958 117.437 173.525 1.00 72.80  ?  172 GLU B CB  1 
ATOM   6556  C CG  . GLU B 1 183 ? 129.149 116.533 173.773 1.00 72.80  ?  172 GLU B CG  1 
ATOM   6557  C CD  . GLU B 1 183 ? 128.743 115.092 173.991 1.00 72.80  ?  172 GLU B CD  1 
ATOM   6558  O OE1 . GLU B 1 183 ? 129.638 114.243 174.181 1.00 72.80  ?  172 GLU B OE1 1 
ATOM   6559  O OE2 . GLU B 1 183 ? 127.528 114.805 173.969 1.00 72.80  -1 172 GLU B OE2 1 
ATOM   6560  N N   . ARG B 1 184 ? 126.340 120.070 173.815 1.00 70.85  ?  173 ARG B N   1 
ATOM   6561  C CA  . ARG B 1 184 ? 125.122 120.828 173.582 1.00 70.85  ?  173 ARG B CA  1 
ATOM   6562  C C   . ARG B 1 184 ? 125.410 122.146 172.888 1.00 70.85  ?  173 ARG B C   1 
ATOM   6563  O O   . ARG B 1 184 ? 124.705 122.529 171.958 1.00 70.85  ?  173 ARG B O   1 
ATOM   6564  C CB  . ARG B 1 184 ? 124.419 121.080 174.913 1.00 70.85  ?  173 ARG B CB  1 
ATOM   6565  C CG  . ARG B 1 184 ? 123.321 122.123 174.856 1.00 70.85  ?  173 ARG B CG  1 
ATOM   6566  C CD  . ARG B 1 184 ? 122.892 122.518 176.257 1.00 70.85  ?  173 ARG B CD  1 
ATOM   6567  N NE  . ARG B 1 184 ? 124.042 122.834 177.098 1.00 70.85  ?  173 ARG B NE  1 
ATOM   6568  C CZ  . ARG B 1 184 ? 124.615 124.031 177.159 1.00 70.85  ?  173 ARG B CZ  1 
ATOM   6569  N NH1 . ARG B 1 184 ? 125.660 124.228 177.951 1.00 70.85  1  173 ARG B NH1 1 
ATOM   6570  N NH2 . ARG B 1 184 ? 124.147 125.029 176.424 1.00 70.85  ?  173 ARG B NH2 1 
ATOM   6571  N N   . VAL B 1 185 ? 126.452 122.836 173.327 1.00 64.74  ?  174 VAL B N   1 
ATOM   6572  C CA  . VAL B 1 185 ? 126.806 124.114 172.729 1.00 64.74  ?  174 VAL B CA  1 
ATOM   6573  C C   . VAL B 1 185 ? 127.254 123.939 171.284 1.00 64.74  ?  174 VAL B C   1 
ATOM   6574  O O   . VAL B 1 185 ? 126.882 124.724 170.415 1.00 64.74  ?  174 VAL B O   1 
ATOM   6575  C CB  . VAL B 1 185 ? 127.901 124.828 173.546 1.00 64.74  ?  174 VAL B CB  1 
ATOM   6576  C CG1 . VAL B 1 185 ? 128.402 126.060 172.814 1.00 64.74  ?  174 VAL B CG1 1 
ATOM   6577  C CG2 . VAL B 1 185 ? 127.370 125.197 174.921 1.00 64.74  ?  174 VAL B CG2 1 
ATOM   6578  N N   . ARG B 1 186 ? 128.044 122.908 171.023 1.00 56.82  ?  175 ARG B N   1 
ATOM   6579  C CA  . ARG B 1 186 ? 128.487 122.651 169.662 1.00 56.82  ?  175 ARG B CA  1 
ATOM   6580  C C   . ARG B 1 186 ? 127.318 122.275 168.757 1.00 56.82  ?  175 ARG B C   1 
ATOM   6581  O O   . ARG B 1 186 ? 127.237 122.731 167.621 1.00 56.82  ?  175 ARG B O   1 
ATOM   6582  C CB  . ARG B 1 186 ? 129.569 121.571 169.637 1.00 56.82  ?  175 ARG B CB  1 
ATOM   6583  C CG  . ARG B 1 186 ? 130.890 122.015 170.237 1.00 56.82  ?  175 ARG B CG  1 
ATOM   6584  C CD  . ARG B 1 186 ? 132.002 121.027 169.933 1.00 56.82  ?  175 ARG B CD  1 
ATOM   6585  N NE  . ARG B 1 186 ? 132.282 120.933 168.503 1.00 56.82  ?  175 ARG B NE  1 
ATOM   6586  C CZ  . ARG B 1 186 ? 133.117 121.733 167.848 1.00 56.82  ?  175 ARG B CZ  1 
ATOM   6587  N NH1 . ARG B 1 186 ? 133.758 122.697 168.491 1.00 56.82  1  175 ARG B NH1 1 
ATOM   6588  N NH2 . ARG B 1 186 ? 133.310 121.571 166.549 1.00 56.82  ?  175 ARG B NH2 1 
ATOM   6589  N N   . VAL B 1 187 ? 126.406 121.461 169.266 1.00 55.82  ?  176 VAL B N   1 
ATOM   6590  C CA  . VAL B 1 187 ? 125.261 121.049 168.471 1.00 55.82  ?  176 VAL B CA  1 
ATOM   6591  C C   . VAL B 1 187 ? 124.398 122.255 168.130 1.00 55.82  ?  176 VAL B C   1 
ATOM   6592  O O   . VAL B 1 187 ? 123.930 122.388 167.005 1.00 55.82  ?  176 VAL B O   1 
ATOM   6593  C CB  . VAL B 1 187 ? 124.428 119.965 169.187 1.00 55.82  ?  176 VAL B CB  1 
ATOM   6594  C CG1 . VAL B 1 187 ? 123.093 119.767 168.487 1.00 55.82  ?  176 VAL B CG1 1 
ATOM   6595  C CG2 . VAL B 1 187 ? 125.199 118.657 169.253 1.00 55.82  ?  176 VAL B CG2 1 
ATOM   6596  N N   . ALA B 1 188 ? 124.209 123.147 169.090 1.00 54.34  ?  177 ALA B N   1 
ATOM   6597  C CA  . ALA B 1 188 ? 123.413 124.341 168.852 1.00 54.34  ?  177 ALA B CA  1 
ATOM   6598  C C   . ALA B 1 188 ? 124.047 125.238 167.801 1.00 54.34  ?  177 ALA B C   1 
ATOM   6599  O O   . ALA B 1 188 ? 123.346 125.814 166.975 1.00 54.34  ?  177 ALA B O   1 
ATOM   6600  C CB  . ALA B 1 188 ? 123.208 125.102 170.150 1.00 54.34  ?  177 ALA B CB  1 
ATOM   6601  N N   . ALA B 1 189 ? 125.366 125.364 167.831 1.00 51.72  ?  178 ALA B N   1 
ATOM   6602  C CA  . ALA B 1 189 ? 126.069 126.184 166.854 1.00 51.72  ?  178 ALA B CA  1 
ATOM   6603  C C   . ALA B 1 189 ? 126.034 125.570 165.454 1.00 51.72  ?  178 ALA B C   1 
ATOM   6604  O O   . ALA B 1 189 ? 125.893 126.292 164.476 1.00 51.72  ?  178 ALA B O   1 
ATOM   6605  C CB  . ALA B 1 189 ? 127.502 126.430 167.307 1.00 51.72  ?  178 ALA B CB  1 
ATOM   6606  N N   . ALA B 1 190 ? 126.150 124.249 165.355 1.00 50.96  ?  179 ALA B N   1 
ATOM   6607  C CA  . ALA B 1 190 ? 126.102 123.569 164.058 1.00 50.96  ?  179 ALA B CA  1 
ATOM   6608  C C   . ALA B 1 190 ? 124.768 123.780 163.357 1.00 50.96  ?  179 ALA B C   1 
ATOM   6609  O O   . ALA B 1 190 ? 124.727 123.859 162.137 1.00 50.96  ?  179 ALA B O   1 
ATOM   6610  C CB  . ALA B 1 190 ? 126.387 122.090 164.238 1.00 50.96  ?  179 ALA B CB  1 
ATOM   6611  N N   . ALA B 1 191 ? 123.686 123.869 164.112 1.00 49.35  ?  180 ALA B N   1 
ATOM   6612  C CA  . ALA B 1 191 ? 122.353 124.106 163.576 1.00 49.35  ?  180 ALA B CA  1 
ATOM   6613  C C   . ALA B 1 191 ? 122.198 125.538 163.078 1.00 49.35  ?  180 ALA B C   1 
ATOM   6614  O O   . ALA B 1 191 ? 121.617 125.775 162.013 1.00 49.35  ?  180 ALA B O   1 
ATOM   6615  C CB  . ALA B 1 191 ? 121.310 123.787 164.640 1.00 49.35  ?  180 ALA B CB  1 
ATOM   6616  N N   . SER B 1 192 ? 122.724 126.512 163.826 1.00 51.65  ?  181 SER B N   1 
ATOM   6617  C CA  . SER B 1 192 ? 122.547 127.905 163.416 1.00 51.65  ?  181 SER B CA  1 
ATOM   6618  C C   . SER B 1 192 ? 123.388 128.238 162.188 1.00 51.65  ?  181 SER B C   1 
ATOM   6619  O O   . SER B 1 192 ? 122.929 128.964 161.295 1.00 51.65  ?  181 SER B O   1 
ATOM   6620  C CB  . SER B 1 192 ? 122.882 128.836 164.575 1.00 51.65  ?  181 SER B CB  1 
ATOM   6621  O OG  . SER B 1 192 ? 122.437 128.280 165.798 1.00 51.65  ?  181 SER B OG  1 
ATOM   6622  N N   . VAL B 1 193 ? 124.614 127.718 162.118 1.00 48.30  ?  182 VAL B N   1 
ATOM   6623  C CA  . VAL B 1 193 ? 125.431 127.899 160.920 1.00 48.30  ?  182 VAL B CA  1 
ATOM   6624  C C   . VAL B 1 193 ? 124.733 127.293 159.710 1.00 48.30  ?  182 VAL B C   1 
ATOM   6625  O O   . VAL B 1 193 ? 124.730 127.874 158.616 1.00 48.30  ?  182 VAL B O   1 
ATOM   6626  C CB  . VAL B 1 193 ? 126.827 127.288 161.137 1.00 48.30  ?  182 VAL B CB  1 
ATOM   6627  C CG1 . VAL B 1 193 ? 127.563 127.171 159.827 1.00 48.30  ?  182 VAL B CG1 1 
ATOM   6628  C CG2 . VAL B 1 193 ? 127.626 128.122 162.122 1.00 48.30  ?  182 VAL B CG2 1 
ATOM   6629  N N   . THR B 1 194 ? 124.115 126.126 159.892 1.00 47.24  ?  183 THR B N   1 
ATOM   6630  C CA  . THR B 1 194 ? 123.401 125.483 158.797 1.00 47.24  ?  183 THR B CA  1 
ATOM   6631  C C   . THR B 1 194 ? 122.219 126.319 158.331 1.00 47.24  ?  183 THR B C   1 
ATOM   6632  O O   . THR B 1 194 ? 122.009 126.485 157.127 1.00 47.24  ?  183 THR B O   1 
ATOM   6633  C CB  . THR B 1 194 ? 122.932 124.106 159.237 1.00 47.24  ?  183 THR B CB  1 
ATOM   6634  O OG1 . THR B 1 194 ? 124.052 123.380 159.741 1.00 47.24  ?  183 THR B OG1 1 
ATOM   6635  C CG2 . THR B 1 194 ? 122.321 123.363 158.081 1.00 47.24  ?  183 THR B CG2 1 
ATOM   6636  N N   . VAL B 1 195 ? 121.426 126.838 159.270 1.00 46.88  ?  184 VAL B N   1 
ATOM   6637  C CA  . VAL B 1 195 ? 120.272 127.647 158.886 1.00 46.88  ?  184 VAL B CA  1 
ATOM   6638  C C   . VAL B 1 195 ? 120.719 128.904 158.152 1.00 46.88  ?  184 VAL B C   1 
ATOM   6639  O O   . VAL B 1 195 ? 120.099 129.313 157.166 1.00 46.88  ?  184 VAL B O   1 
ATOM   6640  C CB  . VAL B 1 195 ? 119.408 127.984 160.114 1.00 46.88  ?  184 VAL B CB  1 
ATOM   6641  C CG1 . VAL B 1 195 ? 118.254 128.869 159.709 1.00 46.88  ?  184 VAL B CG1 1 
ATOM   6642  C CG2 . VAL B 1 195 ? 118.882 126.729 160.739 1.00 46.88  ?  184 VAL B CG2 1 
ATOM   6643  N N   . LEU B 1 196 ? 121.813 129.525 158.600 1.00 46.91  ?  185 LEU B N   1 
ATOM   6644  C CA  . LEU B 1 196 ? 122.271 130.734 157.922 1.00 46.91  ?  185 LEU B CA  1 
ATOM   6645  C C   . LEU B 1 196 ? 122.776 130.437 156.516 1.00 46.91  ?  185 LEU B C   1 
ATOM   6646  O O   . LEU B 1 196 ? 122.478 131.183 155.576 1.00 46.91  ?  185 LEU B O   1 
ATOM   6647  C CB  . LEU B 1 196 ? 123.357 131.429 158.738 1.00 46.91  ?  185 LEU B CB  1 
ATOM   6648  C CG  . LEU B 1 196 ? 123.770 132.796 158.192 1.00 46.91  ?  185 LEU B CG  1 
ATOM   6649  C CD1 . LEU B 1 196 ? 122.565 133.690 158.011 1.00 46.91  ?  185 LEU B CD1 1 
ATOM   6650  C CD2 . LEU B 1 196 ? 124.766 133.447 159.111 1.00 46.91  ?  185 LEU B CD2 1 
ATOM   6651  N N   . SER B 1 197 ? 123.545 129.361 156.343 1.00 46.16  ?  186 SER B N   1 
ATOM   6652  C CA  . SER B 1 197 ? 124.036 129.038 155.006 1.00 46.16  ?  186 SER B CA  1 
ATOM   6653  C C   . SER B 1 197 ? 122.896 128.628 154.081 1.00 46.16  ?  186 SER B C   1 
ATOM   6654  O O   . SER B 1 197 ? 122.905 128.953 152.889 1.00 46.16  ?  186 SER B O   1 
ATOM   6655  C CB  . SER B 1 197 ? 125.095 127.943 155.085 1.00 46.16  ?  186 SER B CB  1 
ATOM   6656  O OG  . SER B 1 197 ? 124.753 126.983 156.061 1.00 46.16  ?  186 SER B OG  1 
ATOM   6657  N N   . GLY B 1 198 ? 121.892 127.933 154.616 1.00 44.75  ?  187 GLY B N   1 
ATOM   6658  C CA  . GLY B 1 198 ? 120.717 127.629 153.820 1.00 44.75  ?  187 GLY B CA  1 
ATOM   6659  C C   . GLY B 1 198 ? 119.944 128.872 153.429 1.00 44.75  ?  187 GLY B C   1 
ATOM   6660  O O   . GLY B 1 198 ? 119.423 128.960 152.319 1.00 44.75  ?  187 GLY B O   1 
ATOM   6661  N N   . ILE B 1 199 ? 119.823 129.814 154.357 1.00 44.99  ?  188 ILE B N   1 
ATOM   6662  C CA  . ILE B 1 199 ? 119.152 131.068 154.065 1.00 44.99  ?  188 ILE B CA  1 
ATOM   6663  C C   . ILE B 1 199 ? 119.917 131.784 152.973 1.00 44.99  ?  188 ILE B C   1 
ATOM   6664  O O   . ILE B 1 199 ? 119.324 132.311 152.042 1.00 44.99  ?  188 ILE B O   1 
ATOM   6665  C CB  . ILE B 1 199 ? 119.060 131.954 155.320 1.00 44.99  ?  188 ILE B CB  1 
ATOM   6666  C CG1 . ILE B 1 199 ? 118.053 131.370 156.310 1.00 44.99  ?  188 ILE B CG1 1 
ATOM   6667  C CG2 . ILE B 1 199 ? 118.673 133.376 154.947 1.00 44.99  ?  188 ILE B CG2 1 
ATOM   6668  C CD1 . ILE B 1 199 ? 118.044 132.067 157.651 1.00 44.99  ?  188 ILE B CD1 1 
ATOM   6669  N N   . ILE B 1 200 ? 121.237 131.787 153.075 1.00 44.11  ?  189 ILE B N   1 
ATOM   6670  C CA  . ILE B 1 200 ? 122.054 132.411 152.052 1.00 44.11  ?  189 ILE B CA  1 
ATOM   6671  C C   . ILE B 1 200 ? 121.821 131.699 150.732 1.00 44.11  ?  189 ILE B C   1 
ATOM   6672  O O   . ILE B 1 200 ? 121.653 132.339 149.703 1.00 44.11  ?  189 ILE B O   1 
ATOM   6673  C CB  . ILE B 1 200 ? 123.547 132.391 152.433 1.00 44.11  ?  189 ILE B CB  1 
ATOM   6674  C CG1 . ILE B 1 200 ? 123.777 133.197 153.711 1.00 44.11  ?  189 ILE B CG1 1 
ATOM   6675  C CG2 . ILE B 1 200 ? 124.403 132.934 151.300 1.00 44.11  ?  189 ILE B CG2 1 
ATOM   6676  C CD1 . ILE B 1 200 ? 125.186 133.106 154.249 1.00 44.11  ?  189 ILE B CD1 1 
ATOM   6677  N N   . GLN B 1 201 ? 121.780 130.377 150.762 1.00 43.92  ?  190 GLN B N   1 
ATOM   6678  C CA  . GLN B 1 201 ? 121.498 129.619 149.552 1.00 43.92  ?  190 GLN B CA  1 
ATOM   6679  C C   . GLN B 1 201 ? 120.109 129.924 149.001 1.00 43.92  ?  190 GLN B C   1 
ATOM   6680  O O   . GLN B 1 201 ? 119.943 130.083 147.797 1.00 43.92  ?  190 GLN B O   1 
ATOM   6681  C CB  . GLN B 1 201 ? 121.652 128.122 149.813 1.00 43.92  ?  190 GLN B CB  1 
ATOM   6682  C CG  . GLN B 1 201 ? 123.089 127.665 149.951 1.00 43.92  ?  190 GLN B CG  1 
ATOM   6683  C CD  . GLN B 1 201 ? 123.195 126.204 150.327 1.00 43.92  ?  190 GLN B CD  1 
ATOM   6684  O OE1 . GLN B 1 201 ? 124.147 125.522 149.951 1.00 43.92  ?  190 GLN B OE1 1 
ATOM   6685  N NE2 . GLN B 1 201 ? 122.214 125.715 151.069 1.00 43.92  ?  190 GLN B NE2 1 
ATOM   6686  N N   . LEU B 1 202 ? 119.116 130.017 149.876 1.00 45.13  ?  191 LEU B N   1 
ATOM   6687  C CA  . LEU B 1 202 ? 117.762 130.323 149.444 1.00 45.13  ?  191 LEU B CA  1 
ATOM   6688  C C   . LEU B 1 202 ? 117.706 131.713 148.836 1.00 45.13  ?  191 LEU B C   1 
ATOM   6689  O O   . LEU B 1 202 ? 117.027 131.927 147.841 1.00 45.13  ?  191 LEU B O   1 
ATOM   6690  C CB  . LEU B 1 202 ? 116.791 130.208 150.617 1.00 45.13  ?  191 LEU B CB  1 
ATOM   6691  C CG  . LEU B 1 202 ? 115.302 130.358 150.316 1.00 45.13  ?  191 LEU B CG  1 
ATOM   6692  C CD1 . LEU B 1 202 ? 114.859 129.340 149.278 1.00 45.13  ?  191 LEU B CD1 1 
ATOM   6693  C CD2 . LEU B 1 202 ? 114.500 130.203 151.596 1.00 45.13  ?  191 LEU B CD2 1 
ATOM   6694  N N   . ALA B 1 203 ? 118.432 132.654 149.420 1.00 44.79  ?  192 ALA B N   1 
ATOM   6695  C CA  . ALA B 1 203 ? 118.459 134.014 148.904 1.00 44.79  ?  192 ALA B CA  1 
ATOM   6696  C C   . ALA B 1 203 ? 119.058 134.074 147.507 1.00 44.79  ?  192 ALA B C   1 
ATOM   6697  O O   . ALA B 1 203 ? 118.498 134.714 146.623 1.00 44.79  ?  192 ALA B O   1 
ATOM   6698  C CB  . ALA B 1 203 ? 119.236 134.904 149.852 1.00 44.79  ?  192 ALA B CB  1 
ATOM   6699  N N   . PHE B 1 204 ? 120.182 133.400 147.299 1.00 46.13  ?  193 PHE B N   1 
ATOM   6700  C CA  . PHE B 1 204 ? 120.839 133.403 145.997 1.00 46.13  ?  193 PHE B CA  1 
ATOM   6701  C C   . PHE B 1 204 ? 119.972 132.793 144.905 1.00 46.13  ?  193 PHE B C   1 
ATOM   6702  O O   . PHE B 1 204 ? 120.026 133.221 143.759 1.00 46.13  ?  193 PHE B O   1 
ATOM   6703  C CB  . PHE B 1 204 ? 122.180 132.669 146.083 1.00 46.13  ?  193 PHE B CB  1 
ATOM   6704  C CG  . PHE B 1 204 ? 123.330 133.556 146.448 1.00 46.13  ?  193 PHE B CG  1 
ATOM   6705  C CD1 . PHE B 1 204 ? 123.483 134.018 147.742 1.00 46.13  ?  193 PHE B CD1 1 
ATOM   6706  C CD2 . PHE B 1 204 ? 124.262 133.924 145.494 1.00 46.13  ?  193 PHE B CD2 1 
ATOM   6707  C CE1 . PHE B 1 204 ? 124.544 134.835 148.080 1.00 46.13  ?  193 PHE B CE1 1 
ATOM   6708  C CE2 . PHE B 1 204 ? 125.325 134.741 145.823 1.00 46.13  ?  193 PHE B CE2 1 
ATOM   6709  C CZ  . PHE B 1 204 ? 125.466 135.197 147.119 1.00 46.13  ?  193 PHE B CZ  1 
ATOM   6710  N N   . GLY B 1 205 ? 119.176 131.793 145.253 1.00 45.99  ?  194 GLY B N   1 
ATOM   6711  C CA  . GLY B 1 205 ? 118.294 131.168 144.285 1.00 45.99  ?  194 GLY B CA  1 
ATOM   6712  C C   . GLY B 1 205 ? 117.076 131.999 143.954 1.00 45.99  ?  194 GLY B C   1 
ATOM   6713  O O   . GLY B 1 205 ? 116.558 131.920 142.837 1.00 45.99  ?  194 GLY B O   1 
ATOM   6714  N N   . ILE B 1 206 ? 116.597 132.796 144.908 1.00 47.75  ?  195 ILE B N   1 
ATOM   6715  C CA  . ILE B 1 206 ? 115.458 133.670 144.653 1.00 47.75  ?  195 ILE B CA  1 
ATOM   6716  C C   . ILE B 1 206 ? 115.865 134.841 143.767 1.00 47.75  ?  195 ILE B C   1 
ATOM   6717  O O   . ILE B 1 206 ? 115.128 135.234 142.856 1.00 47.75  ?  195 ILE B O   1 
ATOM   6718  C CB  . ILE B 1 206 ? 114.853 134.146 145.987 1.00 47.75  ?  195 ILE B CB  1 
ATOM   6719  C CG1 . ILE B 1 206 ? 114.011 133.039 146.612 1.00 47.75  ?  195 ILE B CG1 1 
ATOM   6720  C CG2 . ILE B 1 206 ? 114.021 135.397 145.792 1.00 47.75  ?  195 ILE B CG2 1 
ATOM   6721  C CD1 . ILE B 1 206 ? 113.615 133.326 148.031 1.00 47.75  ?  195 ILE B CD1 1 
ATOM   6722  N N   . LEU B 1 207 ? 117.044 135.412 144.011 1.00 47.93  ?  196 LEU B N   1 
ATOM   6723  C CA  . LEU B 1 207 ? 117.559 136.515 143.211 1.00 47.93  ?  196 LEU B CA  1 
ATOM   6724  C C   . LEU B 1 207 ? 118.110 136.072 141.863 1.00 47.93  ?  196 LEU B C   1 
ATOM   6725  O O   . LEU B 1 207 ? 118.628 136.914 141.125 1.00 47.93  ?  196 LEU B O   1 
ATOM   6726  C CB  . LEU B 1 207 ? 118.648 137.258 143.984 1.00 47.93  ?  196 LEU B CB  1 
ATOM   6727  C CG  . LEU B 1 207 ? 118.283 137.810 145.360 1.00 47.93  ?  196 LEU B CG  1 
ATOM   6728  C CD1 . LEU B 1 207 ? 119.528 138.295 146.071 1.00 47.93  ?  196 LEU B CD1 1 
ATOM   6729  C CD2 . LEU B 1 207 ? 117.270 138.927 145.237 1.00 47.93  ?  196 LEU B CD2 1 
ATOM   6730  N N   . ARG B 1 208 ? 118.018 134.784 141.535 1.00 47.56  ?  197 ARG B N   1 
ATOM   6731  C CA  . ARG B 1 208 ? 118.420 134.245 140.231 1.00 47.56  ?  197 ARG B CA  1 
ATOM   6732  C C   . ARG B 1 208 ? 119.899 134.502 139.943 1.00 47.56  ?  197 ARG B C   1 
ATOM   6733  O O   . ARG B 1 208 ? 120.278 134.922 138.850 1.00 47.56  ?  197 ARG B O   1 
ATOM   6734  C CB  . ARG B 1 208 ? 117.542 134.799 139.103 1.00 47.56  ?  197 ARG B CB  1 
ATOM   6735  C CG  . ARG B 1 208 ? 116.051 134.878 139.397 1.00 47.56  ?  197 ARG B CG  1 
ATOM   6736  C CD  . ARG B 1 208 ? 115.506 133.618 140.047 1.00 47.56  ?  197 ARG B CD  1 
ATOM   6737  N NE  . ARG B 1 208 ? 115.136 132.592 139.080 1.00 47.56  ?  197 ARG B NE  1 
ATOM   6738  C CZ  . ARG B 1 208 ? 114.707 131.380 139.414 1.00 47.56  ?  197 ARG B CZ  1 
ATOM   6739  N NH1 . ARG B 1 208 ? 114.593 131.043 140.690 1.00 47.56  1  197 ARG B NH1 1 
ATOM   6740  N NH2 . ARG B 1 208 ? 114.392 130.502 138.474 1.00 47.56  ?  197 ARG B NH2 1 
ATOM   6741  N N   . ILE B 1 209 ? 120.747 134.219 140.931 1.00 46.72  ?  198 ILE B N   1 
ATOM   6742  C CA  . ILE B 1 209 ? 122.185 134.411 140.784 1.00 46.72  ?  198 ILE B CA  1 
ATOM   6743  C C   . ILE B 1 209 ? 122.845 133.044 140.663 1.00 46.72  ?  198 ILE B C   1 
ATOM   6744  O O   . ILE B 1 209 ? 123.998 132.856 141.059 1.00 46.72  ?  198 ILE B O   1 
ATOM   6745  C CB  . ILE B 1 209 ? 122.776 135.212 141.959 1.00 46.72  ?  198 ILE B CB  1 
ATOM   6746  C CG1 . ILE B 1 209 ? 121.890 136.401 142.304 1.00 46.72  ?  198 ILE B CG1 1 
ATOM   6747  C CG2 . ILE B 1 209 ? 124.132 135.775 141.599 1.00 46.72  ?  198 ILE B CG2 1 
ATOM   6748  C CD1 . ILE B 1 209 ? 122.227 137.027 143.632 1.00 46.72  ?  198 ILE B CD1 1 
ATOM   6749  N N   . GLY B 1 210 ? 122.120 132.076 140.115 1.00 45.86  ?  199 GLY B N   1 
ATOM   6750  C CA  . GLY B 1 210 ? 122.615 130.716 140.038 1.00 45.86  ?  199 GLY B CA  1 
ATOM   6751  C C   . GLY B 1 210 ? 123.780 130.493 139.098 1.00 45.86  ?  199 GLY B C   1 
ATOM   6752  O O   . GLY B 1 210 ? 124.178 129.349 138.866 1.00 45.86  ?  199 GLY B O   1 
ATOM   6753  N N   . PHE B 1 211 ? 124.337 131.571 138.547 1.00 43.83  ?  200 PHE B N   1 
ATOM   6754  C CA  . PHE B 1 211 ? 125.476 131.489 137.647 1.00 43.83  ?  200 PHE B CA  1 
ATOM   6755  C C   . PHE B 1 211 ? 126.791 131.830 138.331 1.00 43.83  ?  200 PHE B C   1 
ATOM   6756  O O   . PHE B 1 211 ? 127.785 132.069 137.646 1.00 43.83  ?  200 PHE B O   1 
ATOM   6757  C CB  . PHE B 1 211 ? 125.268 132.406 136.437 1.00 43.83  ?  200 PHE B CB  1 
ATOM   6758  C CG  . PHE B 1 211 ? 124.977 133.834 136.797 1.00 43.83  ?  200 PHE B CG  1 
ATOM   6759  C CD1 . PHE B 1 211 ? 123.702 134.340 136.681 1.00 43.83  ?  200 PHE B CD1 1 
ATOM   6760  C CD2 . PHE B 1 211 ? 125.981 134.673 137.246 1.00 43.83  ?  200 PHE B CD2 1 
ATOM   6761  C CE1 . PHE B 1 211 ? 123.433 135.644 137.009 1.00 43.83  ?  200 PHE B CE1 1 
ATOM   6762  C CE2 . PHE B 1 211 ? 125.713 135.972 137.582 1.00 43.83  ?  200 PHE B CE2 1 
ATOM   6763  C CZ  . PHE B 1 211 ? 124.439 136.459 137.461 1.00 43.83  ?  200 PHE B CZ  1 
ATOM   6764  N N   . VAL B 1 212 ? 126.816 131.879 139.664 1.00 43.77  ?  201 VAL B N   1 
ATOM   6765  C CA  . VAL B 1 212 ? 128.056 132.187 140.365 1.00 43.77  ?  201 VAL B CA  1 
ATOM   6766  C C   . VAL B 1 212 ? 129.067 131.066 140.213 1.00 43.77  ?  201 VAL B C   1 
ATOM   6767  O O   . VAL B 1 212 ? 130.271 131.294 140.359 1.00 43.77  ?  201 VAL B O   1 
ATOM   6768  C CB  . VAL B 1 212 ? 127.780 132.475 141.854 1.00 43.77  ?  201 VAL B CB  1 
ATOM   6769  C CG1 . VAL B 1 212 ? 127.332 133.907 142.036 1.00 43.77  ?  201 VAL B CG1 1 
ATOM   6770  C CG2 . VAL B 1 212 ? 126.739 131.514 142.394 1.00 43.77  ?  201 VAL B CG2 1 
ATOM   6771  N N   . VAL B 1 213 ? 128.605 129.853 139.899 1.00 43.78  ?  202 VAL B N   1 
ATOM   6772  C CA  . VAL B 1 213 ? 129.504 128.720 139.754 1.00 43.78  ?  202 VAL B CA  1 
ATOM   6773  C C   . VAL B 1 213 ? 130.498 128.917 138.622 1.00 43.78  ?  202 VAL B C   1 
ATOM   6774  O O   . VAL B 1 213 ? 131.495 128.193 138.549 1.00 43.78  ?  202 VAL B O   1 
ATOM   6775  C CB  . VAL B 1 213 ? 128.699 127.427 139.537 1.00 43.78  ?  202 VAL B CB  1 
ATOM   6776  C CG1 . VAL B 1 213 ? 127.859 127.121 140.758 1.00 43.78  ?  202 VAL B CG1 1 
ATOM   6777  C CG2 . VAL B 1 213 ? 127.832 127.550 138.303 1.00 43.78  ?  202 VAL B CG2 1 
ATOM   6778  N N   . ILE B 1 214 ? 130.253 129.877 137.727 1.00 41.57  ?  203 ILE B N   1 
ATOM   6779  C CA  . ILE B 1 214 ? 131.195 130.163 136.654 1.00 41.57  ?  203 ILE B CA  1 
ATOM   6780  C C   . ILE B 1 214 ? 132.422 130.911 137.138 1.00 41.57  ?  203 ILE B C   1 
ATOM   6781  O O   . ILE B 1 214 ? 133.425 130.960 136.422 1.00 41.57  ?  203 ILE B O   1 
ATOM   6782  C CB  . ILE B 1 214 ? 130.514 130.962 135.525 1.00 41.57  ?  203 ILE B CB  1 
ATOM   6783  C CG1 . ILE B 1 214 ? 130.425 132.444 135.889 1.00 41.57  ?  203 ILE B CG1 1 
ATOM   6784  C CG2 . ILE B 1 214 ? 129.150 130.390 135.224 1.00 41.57  ?  203 ILE B CG2 1 
ATOM   6785  C CD1 . ILE B 1 214 ? 129.531 133.246 134.988 1.00 41.57  ?  203 ILE B CD1 1 
ATOM   6786  N N   . TYR B 1 215 ? 132.380 131.484 138.337 1.00 42.22  ?  204 TYR B N   1 
ATOM   6787  C CA  . TYR B 1 215 ? 133.509 132.225 138.878 1.00 42.22  ?  204 TYR B CA  1 
ATOM   6788  C C   . TYR B 1 215 ? 134.546 131.328 139.535 1.00 42.22  ?  204 TYR B C   1 
ATOM   6789  O O   . TYR B 1 215 ? 135.462 131.836 140.186 1.00 42.22  ?  204 TYR B O   1 
ATOM   6790  C CB  . TYR B 1 215 ? 133.022 133.268 139.881 1.00 42.22  ?  204 TYR B CB  1 
ATOM   6791  C CG  . TYR B 1 215 ? 132.087 134.289 139.292 1.00 42.22  ?  204 TYR B CG  1 
ATOM   6792  C CD1 . TYR B 1 215 ? 130.791 134.421 139.761 1.00 42.22  ?  204 TYR B CD1 1 
ATOM   6793  C CD2 . TYR B 1 215 ? 132.495 135.122 138.269 1.00 42.22  ?  204 TYR B CD2 1 
ATOM   6794  C CE1 . TYR B 1 215 ? 129.937 135.353 139.230 1.00 42.22  ?  204 TYR B CE1 1 
ATOM   6795  C CE2 . TYR B 1 215 ? 131.643 136.056 137.733 1.00 42.22  ?  204 TYR B CE2 1 
ATOM   6796  C CZ  . TYR B 1 215 ? 130.369 136.165 138.218 1.00 42.22  ?  204 TYR B CZ  1 
ATOM   6797  O OH  . TYR B 1 215 ? 129.515 137.094 137.685 1.00 42.22  ?  204 TYR B OH  1 
ATOM   6798  N N   . LEU B 1 216 ? 134.423 130.012 139.382 1.00 41.83  ?  205 LEU B N   1 
ATOM   6799  C CA  . LEU B 1 216 ? 135.396 129.056 139.896 1.00 41.83  ?  205 LEU B CA  1 
ATOM   6800  C C   . LEU B 1 216 ? 135.853 128.199 138.726 1.00 41.83  ?  205 LEU B C   1 
ATOM   6801  O O   . LEU B 1 216 ? 135.051 127.465 138.143 1.00 41.83  ?  205 LEU B O   1 
ATOM   6802  C CB  . LEU B 1 216 ? 134.792 128.190 141.000 1.00 41.83  ?  205 LEU B CB  1 
ATOM   6803  C CG  . LEU B 1 216 ? 133.973 128.893 142.078 1.00 41.83  ?  205 LEU B CG  1 
ATOM   6804  C CD1 . LEU B 1 216 ? 133.154 127.887 142.847 1.00 41.83  ?  205 LEU B CD1 1 
ATOM   6805  C CD2 . LEU B 1 216 ? 134.877 129.654 143.014 1.00 41.83  ?  205 LEU B CD2 1 
ATOM   6806  N N   . SER B 1 217 ? 137.131 128.292 138.380 1.00 41.59  ?  206 SER B N   1 
ATOM   6807  C CA  . SER B 1 217 ? 137.651 127.549 137.247 1.00 41.59  ?  206 SER B CA  1 
ATOM   6808  C C   . SER B 1 217 ? 137.894 126.096 137.637 1.00 41.59  ?  206 SER B C   1 
ATOM   6809  O O   . SER B 1 217 ? 137.753 125.696 138.793 1.00 41.59  ?  206 SER B O   1 
ATOM   6810  C CB  . SER B 1 217 ? 138.932 128.193 136.727 1.00 41.59  ?  206 SER B CB  1 
ATOM   6811  O OG  . SER B 1 217 ? 139.662 128.792 137.776 1.00 41.59  ?  206 SER B OG  1 
ATOM   6812  N N   . GLU B 1 218 ? 138.259 125.292 136.639 1.00 46.58  ?  207 GLU B N   1 
ATOM   6813  C CA  . GLU B 1 218 ? 138.575 123.894 136.900 1.00 46.58  ?  207 GLU B CA  1 
ATOM   6814  C C   . GLU B 1 218 ? 139.811 123.754 137.769 1.00 46.58  ?  207 GLU B C   1 
ATOM   6815  O O   . GLU B 1 218 ? 139.855 122.880 138.638 1.00 46.58  ?  207 GLU B O   1 
ATOM   6816  C CB  . GLU B 1 218 ? 138.777 123.147 135.585 1.00 46.58  ?  207 GLU B CB  1 
ATOM   6817  C CG  . GLU B 1 218 ? 137.562 123.109 134.683 1.00 46.58  ?  207 GLU B CG  1 
ATOM   6818  C CD  . GLU B 1 218 ? 137.797 122.267 133.446 1.00 46.58  ?  207 GLU B CD  1 
ATOM   6819  O OE1 . GLU B 1 218 ? 136.812 121.764 132.869 1.00 46.58  ?  207 GLU B OE1 1 
ATOM   6820  O OE2 . GLU B 1 218 ? 138.973 122.105 133.054 1.00 46.58  -1 207 GLU B OE2 1 
ATOM   6821  N N   . SER B 1 219 ? 140.818 124.603 137.559 1.00 42.75  ?  208 SER B N   1 
ATOM   6822  C CA  . SER B 1 219 ? 142.057 124.484 138.318 1.00 42.75  ?  208 SER B CA  1 
ATOM   6823  C C   . SER B 1 219 ? 141.900 125.035 139.730 1.00 42.75  ?  208 SER B C   1 
ATOM   6824  O O   . SER B 1 219 ? 142.494 124.507 140.675 1.00 42.75  ?  208 SER B O   1 
ATOM   6825  C CB  . SER B 1 219 ? 143.188 125.190 137.578 1.00 42.75  ?  208 SER B CB  1 
ATOM   6826  O OG  . SER B 1 219 ? 142.703 126.305 136.861 1.00 42.75  ?  208 SER B OG  1 
ATOM   6827  N N   . LEU B 1 220 ? 141.102 126.090 139.896 1.00 41.69  ?  209 LEU B N   1 
ATOM   6828  C CA  . LEU B 1 220 ? 140.783 126.561 141.238 1.00 41.69  ?  209 LEU B CA  1 
ATOM   6829  C C   . LEU B 1 220 ? 140.072 125.480 142.038 1.00 41.69  ?  209 LEU B C   1 
ATOM   6830  O O   . LEU B 1 220 ? 140.435 125.209 143.187 1.00 41.69  ?  209 LEU B O   1 
ATOM   6831  C CB  . LEU B 1 220 ? 139.927 127.823 141.167 1.00 41.69  ?  209 LEU B CB  1 
ATOM   6832  C CG  . LEU B 1 220 ? 139.621 128.553 142.475 1.00 41.69  ?  209 LEU B CG  1 
ATOM   6833  C CD1 . LEU B 1 220 ? 139.642 130.032 142.249 1.00 41.69  ?  209 LEU B CD1 1 
ATOM   6834  C CD2 . LEU B 1 220 ? 138.280 128.144 143.035 1.00 41.69  ?  209 LEU B CD2 1 
ATOM   6835  N N   . ILE B 1 221 ? 139.063 124.847 141.442 1.00 42.45  ?  210 ILE B N   1 
ATOM   6836  C CA  . ILE B 1 221 ? 138.356 123.770 142.124 1.00 42.45  ?  210 ILE B CA  1 
ATOM   6837  C C   . ILE B 1 221 ? 139.290 122.599 142.390 1.00 42.45  ?  210 ILE B C   1 
ATOM   6838  O O   . ILE B 1 221 ? 139.234 121.979 143.454 1.00 42.45  ?  210 ILE B O   1 
ATOM   6839  C CB  . ILE B 1 221 ? 137.125 123.343 141.307 1.00 42.45  ?  210 ILE B CB  1 
ATOM   6840  C CG1 . ILE B 1 221 ? 136.067 124.443 141.328 1.00 42.45  ?  210 ILE B CG1 1 
ATOM   6841  C CG2 . ILE B 1 221 ? 136.548 122.056 141.844 1.00 42.45  ?  210 ILE B CG2 1 
ATOM   6842  C CD1 . ILE B 1 221 ? 134.953 124.222 140.348 1.00 42.45  ?  210 ILE B CD1 1 
ATOM   6843  N N   . SER B 1 222 ? 140.180 122.296 141.447 1.00 42.31  ?  211 SER B N   1 
ATOM   6844  C CA  . SER B 1 222 ? 141.104 121.182 141.625 1.00 42.31  ?  211 SER B CA  1 
ATOM   6845  C C   . SER B 1 222 ? 142.031 121.415 142.810 1.00 42.31  ?  211 SER B C   1 
ATOM   6846  O O   . SER B 1 222 ? 142.155 120.561 143.696 1.00 42.31  ?  211 SER B O   1 
ATOM   6847  C CB  . SER B 1 222 ? 141.909 120.974 140.345 1.00 42.31  ?  211 SER B CB  1 
ATOM   6848  O OG  . SER B 1 222 ? 142.377 119.647 140.239 1.00 42.31  ?  211 SER B OG  1 
ATOM   6849  N N   . GLY B 1 223 ? 142.692 122.575 142.841 1.00 40.68  ?  212 GLY B N   1 
ATOM   6850  C CA  . GLY B 1 223 ? 143.593 122.874 143.936 1.00 40.68  ?  212 GLY B CA  1 
ATOM   6851  C C   . GLY B 1 223 ? 142.876 122.973 145.265 1.00 40.68  ?  212 GLY B C   1 
ATOM   6852  O O   . GLY B 1 223 ? 143.363 122.471 146.280 1.00 40.68  ?  212 GLY B O   1 
ATOM   6853  N N   . PHE B 1 224 ? 141.691 123.590 145.273 1.00 41.16  ?  213 PHE B N   1 
ATOM   6854  C CA  . PHE B 1 224 ? 140.919 123.696 146.502 1.00 41.16  ?  213 PHE B CA  1 
ATOM   6855  C C   . PHE B 1 224 ? 140.514 122.326 147.022 1.00 41.16  ?  213 PHE B C   1 
ATOM   6856  O O   . PHE B 1 224 ? 140.595 122.065 148.224 1.00 41.16  ?  213 PHE B O   1 
ATOM   6857  C CB  . PHE B 1 224 ? 139.682 124.560 146.273 1.00 41.16  ?  213 PHE B CB  1 
ATOM   6858  C CG  . PHE B 1 224 ? 138.783 124.655 147.470 1.00 41.16  ?  213 PHE B CG  1 
ATOM   6859  C CD1 . PHE B 1 224 ? 139.088 125.509 148.507 1.00 41.16  ?  213 PHE B CD1 1 
ATOM   6860  C CD2 . PHE B 1 224 ? 137.635 123.888 147.562 1.00 41.16  ?  213 PHE B CD2 1 
ATOM   6861  C CE1 . PHE B 1 224 ? 138.276 125.597 149.606 1.00 41.16  ?  213 PHE B CE1 1 
ATOM   6862  C CE2 . PHE B 1 224 ? 136.820 123.975 148.663 1.00 41.16  ?  213 PHE B CE2 1 
ATOM   6863  C CZ  . PHE B 1 224 ? 137.140 124.831 149.684 1.00 41.16  ?  213 PHE B CZ  1 
ATOM   6864  N N   . THR B 1 225 ? 140.103 121.426 146.134 1.00 43.79  ?  214 THR B N   1 
ATOM   6865  C CA  . THR B 1 225 ? 139.612 120.137 146.593 1.00 43.79  ?  214 THR B CA  1 
ATOM   6866  C C   . THR B 1 225 ? 140.738 119.202 147.007 1.00 43.79  ?  214 THR B C   1 
ATOM   6867  O O   . THR B 1 225 ? 140.556 118.414 147.934 1.00 43.79  ?  214 THR B O   1 
ATOM   6868  C CB  . THR B 1 225 ? 138.748 119.485 145.518 1.00 43.79  ?  214 THR B CB  1 
ATOM   6869  O OG1 . THR B 1 225 ? 139.434 119.511 144.263 1.00 43.79  ?  214 THR B OG1 1 
ATOM   6870  C CG2 . THR B 1 225 ? 137.429 120.218 145.387 1.00 43.79  ?  214 THR B CG2 1 
ATOM   6871  N N   . THR B 1 226 ? 141.913 119.276 146.379 1.00 43.81  ?  215 THR B N   1 
ATOM   6872  C CA  . THR B 1 226 ? 143.010 118.445 146.868 1.00 43.81  ?  215 THR B CA  1 
ATOM   6873  C C   . THR B 1 226 ? 143.585 119.008 148.166 1.00 43.81  ?  215 THR B C   1 
ATOM   6874  O O   . THR B 1 226 ? 143.976 118.249 149.063 1.00 43.81  ?  215 THR B O   1 
ATOM   6875  C CB  . THR B 1 226 ? 144.093 118.283 145.805 1.00 43.81  ?  215 THR B CB  1 
ATOM   6876  O OG1 . THR B 1 226 ? 145.219 117.611 146.374 1.00 43.81  ?  215 THR B OG1 1 
ATOM   6877  C CG2 . THR B 1 226 ? 144.537 119.610 145.322 1.00 43.81  ?  215 THR B CG2 1 
ATOM   6878  N N   . ALA B 1 227 ? 143.620 120.339 148.305 1.00 41.70  ?  216 ALA B N   1 
ATOM   6879  C CA  . ALA B 1 227 ? 144.002 120.926 149.585 1.00 41.70  ?  216 ALA B CA  1 
ATOM   6880  C C   . ALA B 1 227 ? 143.015 120.546 150.680 1.00 41.70  ?  216 ALA B C   1 
ATOM   6881  O O   . ALA B 1 227 ? 143.410 120.275 151.819 1.00 41.70  ?  216 ALA B O   1 
ATOM   6882  C CB  . ALA B 1 227 ? 144.095 122.442 149.455 1.00 41.70  ?  216 ALA B CB  1 
ATOM   6883  N N   . ALA B 1 228 ? 141.725 120.501 150.352 1.00 43.63  ?  217 ALA B N   1 
ATOM   6884  C CA  . ALA B 1 228 ? 140.724 120.095 151.328 1.00 43.63  ?  217 ALA B CA  1 
ATOM   6885  C C   . ALA B 1 228 ? 140.809 118.607 151.631 1.00 43.63  ?  217 ALA B C   1 
ATOM   6886  O O   . ALA B 1 228 ? 140.506 118.190 152.750 1.00 43.63  ?  217 ALA B O   1 
ATOM   6887  C CB  . ALA B 1 228 ? 139.334 120.457 150.822 1.00 43.63  ?  217 ALA B CB  1 
ATOM   6888  N N   . ALA B 1 229 ? 141.215 117.794 150.660 1.00 44.44  ?  218 ALA B N   1 
ATOM   6889  C CA  . ALA B 1 229 ? 141.447 116.384 150.938 1.00 44.44  ?  218 ALA B CA  1 
ATOM   6890  C C   . ALA B 1 229 ? 142.623 116.201 151.882 1.00 44.44  ?  218 ALA B C   1 
ATOM   6891  O O   . ALA B 1 229 ? 142.604 115.313 152.739 1.00 44.44  ?  218 ALA B O   1 
ATOM   6892  C CB  . ALA B 1 229 ? 141.676 115.619 149.639 1.00 44.44  ?  218 ALA B CB  1 
ATOM   6893  N N   . VAL B 1 230 ? 143.653 117.036 151.752 1.00 44.24  ?  219 VAL B N   1 
ATOM   6894  C CA  . VAL B 1 230 ? 144.751 117.000 152.718 1.00 44.24  ?  219 VAL B CA  1 
ATOM   6895  C C   . VAL B 1 230 ? 144.267 117.451 154.093 1.00 44.24  ?  219 VAL B C   1 
ATOM   6896  O O   . VAL B 1 230 ? 144.652 116.881 155.121 1.00 44.24  ?  219 VAL B O   1 
ATOM   6897  C CB  . VAL B 1 230 ? 145.929 117.851 152.216 1.00 44.24  ?  219 VAL B CB  1 
ATOM   6898  C CG1 . VAL B 1 230 ? 147.014 117.921 153.259 1.00 44.24  ?  219 VAL B CG1 1 
ATOM   6899  C CG2 . VAL B 1 230 ? 146.483 117.270 150.934 1.00 44.24  ?  219 VAL B CG2 1 
ATOM   6900  N N   . HIS B 1 231 ? 143.406 118.472 154.129 1.00 43.97  ?  220 HIS B N   1 
ATOM   6901  C CA  . HIS B 1 231 ? 142.784 118.903 155.381 1.00 43.97  ?  220 HIS B CA  1 
ATOM   6902  C C   . HIS B 1 231 ? 142.041 117.757 156.053 1.00 43.97  ?  220 HIS B C   1 
ATOM   6903  O O   . HIS B 1 231 ? 142.155 117.553 157.264 1.00 43.97  ?  220 HIS B O   1 
ATOM   6904  C CB  . HIS B 1 231 ? 141.811 120.050 155.116 1.00 43.97  ?  220 HIS B CB  1 
ATOM   6905  C CG  . HIS B 1 231 ? 142.425 121.413 155.176 1.00 43.97  ?  220 HIS B CG  1 
ATOM   6906  N ND1 . HIS B 1 231 ? 142.655 122.074 156.361 1.00 43.97  ?  220 HIS B ND1 1 
ATOM   6907  C CD2 . HIS B 1 231 ? 142.812 122.257 154.193 1.00 43.97  ?  220 HIS B CD2 1 
ATOM   6908  C CE1 . HIS B 1 231 ? 143.177 123.259 156.107 1.00 43.97  ?  220 HIS B CE1 1 
ATOM   6909  N NE2 . HIS B 1 231 ? 143.284 123.395 154.799 1.00 43.97  ?  220 HIS B NE2 1 
ATOM   6910  N N   . VAL B 1 232 ? 141.253 117.013 155.278 1.00 46.95  ?  221 VAL B N   1 
ATOM   6911  C CA  . VAL B 1 232 ? 140.452 115.927 155.837 1.00 46.95  ?  221 VAL B CA  1 
ATOM   6912  C C   . VAL B 1 232 ? 141.342 114.770 156.270 1.00 46.95  ?  221 VAL B C   1 
ATOM   6913  O O   . VAL B 1 232 ? 141.106 114.145 157.307 1.00 46.95  ?  221 VAL B O   1 
ATOM   6914  C CB  . VAL B 1 232 ? 139.384 115.477 154.825 1.00 46.95  ?  221 VAL B CB  1 
ATOM   6915  C CG1 . VAL B 1 232 ? 138.642 114.261 155.340 1.00 46.95  ?  221 VAL B CG1 1 
ATOM   6916  C CG2 . VAL B 1 232 ? 138.419 116.607 154.551 1.00 46.95  ?  221 VAL B CG2 1 
ATOM   6917  N N   . LEU B 1 233 ? 142.373 114.466 155.483 1.00 48.01  ?  222 LEU B N   1 
ATOM   6918  C CA  . LEU B 1 233 ? 143.362 113.473 155.890 1.00 48.01  ?  222 LEU B CA  1 
ATOM   6919  C C   . LEU B 1 233 ? 143.951 113.822 157.249 1.00 48.01  ?  222 LEU B C   1 
ATOM   6920  O O   . LEU B 1 233 ? 144.085 112.959 158.122 1.00 48.01  ?  222 LEU B O   1 
ATOM   6921  C CB  . LEU B 1 233 ? 144.461 113.388 154.830 1.00 48.01  ?  222 LEU B CB  1 
ATOM   6922  C CG  . LEU B 1 233 ? 145.243 112.107 154.553 1.00 48.01  ?  222 LEU B CG  1 
ATOM   6923  C CD1 . LEU B 1 233 ? 146.248 112.392 153.463 1.00 48.01  ?  222 LEU B CD1 1 
ATOM   6924  C CD2 . LEU B 1 233 ? 145.949 111.600 155.788 1.00 48.01  ?  222 LEU B CD2 1 
ATOM   6925  N N   . VAL B 1 234 ? 144.311 115.089 157.445 1.00 49.12  ?  223 VAL B N   1 
ATOM   6926  C CA  . VAL B 1 234 ? 144.860 115.508 158.730 1.00 49.12  ?  223 VAL B CA  1 
ATOM   6927  C C   . VAL B 1 234 ? 143.802 115.429 159.824 1.00 49.12  ?  223 VAL B C   1 
ATOM   6928  O O   . VAL B 1 234 ? 144.108 115.077 160.968 1.00 49.12  ?  223 VAL B O   1 
ATOM   6929  C CB  . VAL B 1 234 ? 145.453 116.922 158.609 1.00 49.12  ?  223 VAL B CB  1 
ATOM   6930  C CG1 . VAL B 1 234 ? 145.690 117.525 159.975 1.00 49.12  ?  223 VAL B CG1 1 
ATOM   6931  C CG2 . VAL B 1 234 ? 146.738 116.882 157.805 1.00 49.12  ?  223 VAL B CG2 1 
ATOM   6932  N N   . SER B 1 235 ? 142.545 115.726 159.495 1.00 50.75  ?  224 SER B N   1 
ATOM   6933  C CA  . SER B 1 235 ? 141.483 115.724 160.491 1.00 50.75  ?  224 SER B CA  1 
ATOM   6934  C C   . SER B 1 235 ? 141.123 114.331 160.981 1.00 50.75  ?  224 SER B C   1 
ATOM   6935  O O   . SER B 1 235 ? 140.620 114.199 162.098 1.00 50.75  ?  224 SER B O   1 
ATOM   6936  C CB  . SER B 1 235 ? 140.234 116.395 159.929 1.00 50.75  ?  224 SER B CB  1 
ATOM   6937  O OG  . SER B 1 235 ? 140.369 117.802 159.960 1.00 50.75  ?  224 SER B OG  1 
ATOM   6938  N N   . GLN B 1 236 ? 141.356 113.297 160.183 1.00 53.10  ?  225 GLN B N   1 
ATOM   6939  C CA  . GLN B 1 236 ? 141.038 111.941 160.602 1.00 53.10  ?  225 GLN B CA  1 
ATOM   6940  C C   . GLN B 1 236 ? 142.125 111.317 161.459 1.00 53.10  ?  225 GLN B C   1 
ATOM   6941  O O   . GLN B 1 236 ? 141.967 110.172 161.879 1.00 53.10  ?  225 GLN B O   1 
ATOM   6942  C CB  . GLN B 1 236 ? 140.791 111.049 159.383 1.00 53.10  ?  225 GLN B CB  1 
ATOM   6943  C CG  . GLN B 1 236 ? 139.748 111.570 158.417 1.00 53.10  ?  225 GLN B CG  1 
ATOM   6944  C CD  . GLN B 1 236 ? 138.342 111.453 158.949 1.00 53.10  ?  225 GLN B CD  1 
ATOM   6945  O OE1 . GLN B 1 236 ? 138.100 110.804 159.962 1.00 53.10  ?  225 GLN B OE1 1 
ATOM   6946  N NE2 . GLN B 1 236 ? 137.401 112.085 158.268 1.00 53.10  ?  225 GLN B NE2 1 
ATOM   6947  N N   . LEU B 1 237 ? 143.211 112.037 161.737 1.00 52.01  ?  226 LEU B N   1 
ATOM   6948  C CA  . LEU B 1 237 ? 144.318 111.441 162.474 1.00 52.01  ?  226 LEU B CA  1 
ATOM   6949  C C   . LEU B 1 237 ? 143.991 111.272 163.949 1.00 52.01  ?  226 LEU B C   1 
ATOM   6950  O O   . LEU B 1 237 ? 144.446 110.309 164.573 1.00 52.01  ?  226 LEU B O   1 
ATOM   6951  C CB  . LEU B 1 237 ? 145.578 112.287 162.303 1.00 52.01  ?  226 LEU B CB  1 
ATOM   6952  C CG  . LEU B 1 237 ? 146.178 112.341 160.901 1.00 52.01  ?  226 LEU B CG  1 
ATOM   6953  C CD1 . LEU B 1 237 ? 147.495 113.083 160.916 1.00 52.01  ?  226 LEU B CD1 1 
ATOM   6954  C CD2 . LEU B 1 237 ? 146.357 110.942 160.349 1.00 52.01  ?  226 LEU B CD2 1 
ATOM   6955  N N   . LYS B 1 238 ? 143.211 112.183 164.526 1.00 52.40  ?  227 LYS B N   1 
ATOM   6956  C CA  . LYS B 1 238 ? 142.824 112.043 165.923 1.00 52.40  ?  227 LYS B CA  1 
ATOM   6957  C C   . LYS B 1 238 ? 141.899 110.860 166.162 1.00 52.40  ?  227 LYS B C   1 
ATOM   6958  O O   . LYS B 1 238 ? 141.723 110.463 167.316 1.00 52.40  ?  227 LYS B O   1 
ATOM   6959  C CB  . LYS B 1 238 ? 142.155 113.321 166.419 1.00 52.40  ?  227 LYS B CB  1 
ATOM   6960  C CG  . LYS B 1 238 ? 140.950 113.736 165.624 1.00 52.40  ?  227 LYS B CG  1 
ATOM   6961  C CD  . LYS B 1 238 ? 140.329 114.988 166.198 1.00 52.40  ?  227 LYS B CD  1 
ATOM   6962  C CE  . LYS B 1 238 ? 139.827 114.751 167.606 1.00 52.40  ?  227 LYS B CE  1 
ATOM   6963  N NZ  . LYS B 1 238 ? 139.273 115.989 168.214 1.00 52.40  1  227 LYS B NZ  1 
ATOM   6964  N N   . PHE B 1 239 ? 141.306 110.295 165.111 1.00 51.75  ?  228 PHE B N   1 
ATOM   6965  C CA  . PHE B 1 239 ? 140.424 109.143 165.239 1.00 51.75  ?  228 PHE B CA  1 
ATOM   6966  C C   . PHE B 1 239 ? 141.109 107.828 164.911 1.00 51.75  ?  228 PHE B C   1 
ATOM   6967  O O   . PHE B 1 239 ? 140.765 106.802 165.503 1.00 51.75  ?  228 PHE B O   1 
ATOM   6968  C CB  . PHE B 1 239 ? 139.195 109.317 164.343 1.00 51.75  ?  228 PHE B CB  1 
ATOM   6969  C CG  . PHE B 1 239 ? 138.363 110.512 164.692 1.00 51.75  ?  228 PHE B CG  1 
ATOM   6970  C CD1 . PHE B 1 239 ? 137.667 110.565 165.883 1.00 51.75  ?  228 PHE B CD1 1 
ATOM   6971  C CD2 . PHE B 1 239 ? 138.285 111.589 163.831 1.00 51.75  ?  228 PHE B CD2 1 
ATOM   6972  C CE1 . PHE B 1 239 ? 136.912 111.664 166.206 1.00 51.75  ?  228 PHE B CE1 1 
ATOM   6973  C CE2 . PHE B 1 239 ? 137.529 112.690 164.151 1.00 51.75  ?  228 PHE B CE2 1 
ATOM   6974  C CZ  . PHE B 1 239 ? 136.846 112.729 165.339 1.00 51.75  ?  228 PHE B CZ  1 
ATOM   6975  N N   . ILE B 1 240 ? 142.066 107.833 163.980 1.00 55.65  ?  229 ILE B N   1 
ATOM   6976  C CA  . ILE B 1 240 ? 142.871 106.643 163.733 1.00 55.65  ?  229 ILE B CA  1 
ATOM   6977  C C   . ILE B 1 240 ? 143.704 106.302 164.958 1.00 55.65  ?  229 ILE B C   1 
ATOM   6978  O O   . ILE B 1 240 ? 143.751 105.143 165.383 1.00 55.65  ?  229 ILE B O   1 
ATOM   6979  C CB  . ILE B 1 240 ? 143.769 106.844 162.500 1.00 55.65  ?  229 ILE B CB  1 
ATOM   6980  C CG1 . ILE B 1 240 ? 142.954 107.322 161.302 1.00 55.65  ?  229 ILE B CG1 1 
ATOM   6981  C CG2 . ILE B 1 240 ? 144.501 105.565 162.163 1.00 55.65  ?  229 ILE B CG2 1 
ATOM   6982  C CD1 . ILE B 1 240 ? 141.865 106.392 160.896 1.00 55.65  ?  229 ILE B CD1 1 
ATOM   6983  N N   . PHE B 1 241 ? 144.371 107.296 165.544 1.00 55.71  ?  230 PHE B N   1 
ATOM   6984  C CA  . PHE B 1 241 ? 145.204 107.099 166.718 1.00 55.71  ?  230 PHE B CA  1 
ATOM   6985  C C   . PHE B 1 241 ? 144.440 107.171 168.030 1.00 55.71  ?  230 PHE B C   1 
ATOM   6986  O O   . PHE B 1 241 ? 144.946 106.683 169.044 1.00 55.71  ?  230 PHE B O   1 
ATOM   6987  C CB  . PHE B 1 241 ? 146.330 108.143 166.758 1.00 55.71  ?  230 PHE B CB  1 
ATOM   6988  C CG  . PHE B 1 241 ? 147.123 108.244 165.487 1.00 55.71  ?  230 PHE B CG  1 
ATOM   6989  C CD1 . PHE B 1 241 ? 147.592 107.115 164.849 1.00 55.71  ?  230 PHE B CD1 1 
ATOM   6990  C CD2 . PHE B 1 241 ? 147.414 109.476 164.940 1.00 55.71  ?  230 PHE B CD2 1 
ATOM   6991  C CE1 . PHE B 1 241 ? 148.324 107.218 163.689 1.00 55.71  ?  230 PHE B CE1 1 
ATOM   6992  C CE2 . PHE B 1 241 ? 148.147 109.580 163.779 1.00 55.71  ?  230 PHE B CE2 1 
ATOM   6993  C CZ  . PHE B 1 241 ? 148.600 108.450 163.155 1.00 55.71  ?  230 PHE B CZ  1 
ATOM   6994  N N   . GLN B 1 242 ? 143.242 107.762 168.033 1.00 59.98  ?  231 GLN B N   1 
ATOM   6995  C CA  . GLN B 1 242 ? 142.461 108.018 169.242 1.00 59.98  ?  231 GLN B CA  1 
ATOM   6996  C C   . GLN B 1 242 ? 143.172 108.983 170.184 1.00 59.98  ?  231 GLN B C   1 
ATOM   6997  O O   . GLN B 1 242 ? 143.414 108.662 171.348 1.00 59.98  ?  231 GLN B O   1 
ATOM   6998  C CB  . GLN B 1 242 ? 142.096 106.726 169.976 1.00 59.98  ?  231 GLN B CB  1 
ATOM   6999  C CG  . GLN B 1 242 ? 140.899 106.860 170.894 1.00 59.98  ?  231 GLN B CG  1 
ATOM   7000  C CD  . GLN B 1 242 ? 140.799 105.718 171.871 1.00 59.98  ?  231 GLN B CD  1 
ATOM   7001  O OE1 . GLN B 1 242 ? 141.317 104.635 171.625 1.00 59.98  ?  231 GLN B OE1 1 
ATOM   7002  N NE2 . GLN B 1 242 ? 140.139 105.958 172.994 1.00 59.98  ?  231 GLN B NE2 1 
ATOM   7003  N N   . LEU B 1 243 ? 143.528 110.158 169.681 1.00 57.05  ?  232 LEU B N   1 
ATOM   7004  C CA  . LEU B 1 243 ? 144.129 111.202 170.491 1.00 57.05  ?  232 LEU B CA  1 
ATOM   7005  C C   . LEU B 1 243 ? 143.124 112.324 170.731 1.00 57.05  ?  232 LEU B C   1 
ATOM   7006  O O   . LEU B 1 243 ? 142.087 112.411 170.075 1.00 57.05  ?  232 LEU B O   1 
ATOM   7007  C CB  . LEU B 1 243 ? 145.387 111.744 169.818 1.00 57.05  ?  232 LEU B CB  1 
ATOM   7008  C CG  . LEU B 1 243 ? 146.403 110.684 169.391 1.00 57.05  ?  232 LEU B CG  1 
ATOM   7009  C CD1 . LEU B 1 243 ? 147.358 111.241 168.364 1.00 57.05  ?  232 LEU B CD1 1 
ATOM   7010  C CD2 . LEU B 1 243 ? 147.164 110.153 170.585 1.00 57.05  ?  232 LEU B CD2 1 
ATOM   7011  N N   . THR B 1 244 ? 143.444 113.182 171.695 1.00 58.89  ?  233 THR B N   1 
ATOM   7012  C CA  . THR B 1 244 ? 142.595 114.309 172.062 1.00 58.89  ?  233 THR B CA  1 
ATOM   7013  C C   . THR B 1 244 ? 143.244 115.586 171.545 1.00 58.89  ?  233 THR B C   1 
ATOM   7014  O O   . THR B 1 244 ? 144.269 116.027 172.075 1.00 58.89  ?  233 THR B O   1 
ATOM   7015  C CB  . THR B 1 244 ? 142.391 114.369 173.572 1.00 58.89  ?  233 THR B CB  1 
ATOM   7016  O OG1 . THR B 1 244 ? 141.747 113.169 174.013 1.00 58.89  ?  233 THR B OG1 1 
ATOM   7017  C CG2 . THR B 1 244 ? 141.520 115.552 173.936 1.00 58.89  ?  233 THR B CG2 1 
ATOM   7018  N N   . VAL B 1 245 ? 142.650 116.173 170.521 1.00 55.25  ?  234 VAL B N   1 
ATOM   7019  C CA  . VAL B 1 245 ? 143.188 117.348 169.840 1.00 55.25  ?  234 VAL B CA  1 
ATOM   7020  C C   . VAL B 1 245 ? 142.233 118.509 170.081 1.00 55.25  ?  234 VAL B C   1 
ATOM   7021  O O   . VAL B 1 245 ? 141.016 118.326 169.966 1.00 55.25  ?  234 VAL B O   1 
ATOM   7022  C CB  . VAL B 1 245 ? 143.369 117.094 168.330 1.00 55.25  ?  234 VAL B CB  1 
ATOM   7023  C CG1 . VAL B 1 245 ? 143.827 118.349 167.616 1.00 55.25  ?  234 VAL B CG1 1 
ATOM   7024  C CG2 . VAL B 1 245 ? 144.346 115.956 168.104 1.00 55.25  ?  234 VAL B CG2 1 
ATOM   7025  N N   . PRO B 1 246 ? 142.727 119.699 170.431 1.00 55.12  ?  235 PRO B N   1 
ATOM   7026  C CA  . PRO B 1 246 ? 141.831 120.846 170.633 1.00 55.12  ?  235 PRO B CA  1 
ATOM   7027  C C   . PRO B 1 246 ? 141.078 121.256 169.379 1.00 55.12  ?  235 PRO B C   1 
ATOM   7028  O O   . PRO B 1 246 ? 141.353 120.759 168.284 1.00 55.12  ?  235 PRO B O   1 
ATOM   7029  C CB  . PRO B 1 246 ? 142.787 121.956 171.087 1.00 55.12  ?  235 PRO B CB  1 
ATOM   7030  C CG  . PRO B 1 246 ? 143.945 121.239 171.665 1.00 55.12  ?  235 PRO B CG  1 
ATOM   7031  C CD  . PRO B 1 246 ? 144.105 119.999 170.847 1.00 55.12  ?  235 PRO B CD  1 
ATOM   7032  N N   . SER B 1 247 ? 140.122 122.168 169.531 1.00 54.91  ?  236 SER B N   1 
ATOM   7033  C CA  . SER B 1 247 ? 139.357 122.685 168.399 1.00 54.91  ?  236 SER B CA  1 
ATOM   7034  C C   . SER B 1 247 ? 140.101 123.894 167.853 1.00 54.91  ?  236 SER B C   1 
ATOM   7035  O O   . SER B 1 247 ? 139.805 125.040 168.187 1.00 54.91  ?  236 SER B O   1 
ATOM   7036  C CB  . SER B 1 247 ? 137.935 123.036 168.818 1.00 54.91  ?  236 SER B CB  1 
ATOM   7037  O OG  . SER B 1 247 ? 137.196 121.871 169.135 1.00 54.91  ?  236 SER B OG  1 
ATOM   7038  N N   . HIS B 1 248 ? 141.092 123.577 167.036 1.00 54.57  ?  237 HIS B N   1 
ATOM   7039  C CA  . HIS B 1 248 ? 141.946 124.546 166.414 1.00 54.57  ?  237 HIS B CA  1 
ATOM   7040  C C   . HIS B 1 248 ? 141.171 125.286 165.363 1.00 54.57  ?  237 HIS B C   1 
ATOM   7041  O O   . HIS B 1 248 ? 140.268 124.756 164.758 1.00 54.57  ?  237 HIS B O   1 
ATOM   7042  C CB  . HIS B 1 248 ? 143.150 123.858 165.786 1.00 54.57  ?  237 HIS B CB  1 
ATOM   7043  C CG  . HIS B 1 248 ? 144.036 123.168 166.772 1.00 54.57  ?  237 HIS B CG  1 
ATOM   7044  N ND1 . HIS B 1 248 ? 144.677 123.835 167.789 1.00 54.57  ?  237 HIS B ND1 1 
ATOM   7045  C CD2 . HIS B 1 248 ? 144.401 121.873 166.887 1.00 54.57  ?  237 HIS B CD2 1 
ATOM   7046  C CE1 . HIS B 1 248 ? 145.398 122.982 168.486 1.00 54.57  ?  237 HIS B CE1 1 
ATOM   7047  N NE2 . HIS B 1 248 ? 145.248 121.785 167.958 1.00 54.57  ?  237 HIS B NE2 1 
ATOM   7048  N N   . THR B 1 249 ? 141.556 126.519 165.129 1.00 55.49  ?  238 THR B N   1 
ATOM   7049  C CA  . THR B 1 249 ? 140.897 127.343 164.149 1.00 55.49  ?  238 THR B CA  1 
ATOM   7050  C C   . THR B 1 249 ? 141.938 127.852 163.175 1.00 55.49  ?  238 THR B C   1 
ATOM   7051  O O   . THR B 1 249 ? 143.130 127.726 163.399 1.00 55.49  ?  238 THR B O   1 
ATOM   7052  C CB  . THR B 1 249 ? 140.135 128.509 164.797 1.00 55.49  ?  238 THR B CB  1 
ATOM   7053  O OG1 . THR B 1 249 ? 140.974 129.169 165.749 1.00 55.49  ?  238 THR B OG1 1 
ATOM   7054  C CG2 . THR B 1 249 ? 138.895 128.003 165.496 1.00 55.49  ?  238 THR B CG2 1 
ATOM   7055  N N   . ASP B 1 250 ? 141.489 128.352 162.046 1.00 54.88  ?  239 ASP B N   1 
ATOM   7056  C CA  . ASP B 1 250 ? 142.410 128.881 161.064 1.00 54.88  ?  239 ASP B CA  1 
ATOM   7057  C C   . ASP B 1 250 ? 142.882 130.272 161.466 1.00 54.88  ?  239 ASP B C   1 
ATOM   7058  O O   . ASP B 1 250 ? 142.203 130.950 162.213 1.00 54.88  ?  239 ASP B O   1 
ATOM   7059  C CB  . ASP B 1 250 ? 141.759 128.834 159.691 1.00 54.88  ?  239 ASP B CB  1 
ATOM   7060  C CG  . ASP B 1 250 ? 141.737 127.444 159.137 1.00 54.88  ?  239 ASP B CG  1 
ATOM   7061  O OD1 . ASP B 1 250 ? 142.805 126.815 159.143 1.00 54.88  ?  239 ASP B OD1 1 
ATOM   7062  O OD2 . ASP B 1 250 ? 140.669 126.970 158.701 1.00 54.88  -1 239 ASP B OD2 1 
ATOM   7063  N N   . PRO B 1 251 ? 144.074 130.684 161.016 1.00 54.55  ?  240 PRO B N   1 
ATOM   7064  C CA  . PRO B 1 251 ? 144.899 130.089 159.963 1.00 54.55  ?  240 PRO B CA  1 
ATOM   7065  C C   . PRO B 1 251 ? 145.749 128.948 160.441 1.00 54.55  ?  240 PRO B C   1 
ATOM   7066  O O   . PRO B 1 251 ? 145.889 128.751 161.623 1.00 54.55  ?  240 PRO B O   1 
ATOM   7067  C CB  . PRO B 1 251 ? 145.800 131.247 159.538 1.00 54.55  ?  240 PRO B CB  1 
ATOM   7068  C CG  . PRO B 1 251 ? 145.923 132.076 160.758 1.00 54.55  ?  240 PRO B CG  1 
ATOM   7069  C CD  . PRO B 1 251 ? 144.589 131.996 161.429 1.00 54.55  ?  240 PRO B CD  1 
ATOM   7070  N N   . VAL B 1 252 ? 146.220 128.140 159.506 1.00 51.47  ?  241 VAL B N   1 
ATOM   7071  C CA  . VAL B 1 252 ? 147.121 127.026 159.771 1.00 51.47  ?  241 VAL B CA  1 
ATOM   7072  C C   . VAL B 1 252 ? 146.608 125.978 160.750 1.00 51.47  ?  241 VAL B C   1 
ATOM   7073  O O   . VAL B 1 252 ? 147.386 125.328 161.398 1.00 51.47  ?  241 VAL B O   1 
ATOM   7074  C CB  . VAL B 1 252 ? 148.509 127.525 160.214 1.00 51.47  ?  241 VAL B CB  1 
ATOM   7075  C CG1 . VAL B 1 252 ? 149.518 126.399 160.135 1.00 51.47  ?  241 VAL B CG1 1 
ATOM   7076  C CG2 . VAL B 1 252 ? 148.974 128.660 159.327 1.00 51.47  ?  241 VAL B CG2 1 
ATOM   7077  N N   . SER B 1 253 ? 145.309 125.763 160.804 1.00 51.78  ?  242 SER B N   1 
ATOM   7078  C CA  . SER B 1 253 ? 144.767 124.785 161.701 1.00 51.78  ?  242 SER B CA  1 
ATOM   7079  C C   . SER B 1 253 ? 145.234 123.396 161.336 1.00 51.78  ?  242 SER B C   1 
ATOM   7080  O O   . SER B 1 253 ? 145.324 122.548 162.197 1.00 51.78  ?  242 SER B O   1 
ATOM   7081  C CB  . SER B 1 253 ? 143.245 124.865 161.753 1.00 51.78  ?  242 SER B CB  1 
ATOM   7082  O OG  . SER B 1 253 ? 142.662 124.674 160.492 1.00 51.78  ?  242 SER B OG  1 
ATOM   7083  N N   . ILE B 1 254 ? 145.531 123.147 160.070 1.00 47.88  ?  243 ILE B N   1 
ATOM   7084  C CA  . ILE B 1 254 ? 145.992 121.813 159.718 1.00 47.88  ?  243 ILE B CA  1 
ATOM   7085  C C   . ILE B 1 254 ? 147.314 121.476 160.394 1.00 47.88  ?  243 ILE B C   1 
ATOM   7086  O O   . ILE B 1 254 ? 147.524 120.344 160.812 1.00 47.88  ?  243 ILE B O   1 
ATOM   7087  C CB  . ILE B 1 254 ? 146.098 121.674 158.177 1.00 47.88  ?  243 ILE B CB  1 
ATOM   7088  C CG1 . ILE B 1 254 ? 146.261 120.213 157.769 1.00 47.88  ?  243 ILE B CG1 1 
ATOM   7089  C CG2 . ILE B 1 254 ? 147.237 122.525 157.631 1.00 47.88  ?  243 ILE B CG2 1 
ATOM   7090  C CD1 . ILE B 1 254 ? 146.152 119.988 156.278 1.00 47.88  ?  243 ILE B CD1 1 
ATOM   7091  N N   . PHE B 1 255 ? 148.200 122.455 160.501 1.00 49.74  ?  244 PHE B N   1 
ATOM   7092  C CA  . PHE B 1 255 ? 149.496 122.240 161.143 1.00 49.74  ?  244 PHE B CA  1 
ATOM   7093  C C   . PHE B 1 255 ? 149.356 122.133 162.654 1.00 49.74  ?  244 PHE B C   1 
ATOM   7094  O O   . PHE B 1 255 ? 150.046 121.340 163.283 1.00 49.74  ?  244 PHE B O   1 
ATOM   7095  C CB  . PHE B 1 255 ? 150.472 123.347 160.745 1.00 49.74  ?  244 PHE B CB  1 
ATOM   7096  C CG  . PHE B 1 255 ? 150.851 123.320 159.295 1.00 49.74  ?  244 PHE B CG  1 
ATOM   7097  C CD1 . PHE B 1 255 ? 151.817 122.446 158.838 1.00 49.74  ?  244 PHE B CD1 1 
ATOM   7098  C CD2 . PHE B 1 255 ? 150.236 124.165 158.388 1.00 49.74  ?  244 PHE B CD2 1 
ATOM   7099  C CE1 . PHE B 1 255 ? 152.166 122.415 157.502 1.00 49.74  ?  244 PHE B CE1 1 
ATOM   7100  C CE2 . PHE B 1 255 ? 150.581 124.142 157.053 1.00 49.74  ?  244 PHE B CE2 1 
ATOM   7101  C CZ  . PHE B 1 255 ? 151.547 123.265 156.609 1.00 49.74  ?  244 PHE B CZ  1 
ATOM   7102  N N   . LYS B 1 256 ? 148.454 122.912 163.238 1.00 50.43  ?  245 LYS B N   1 
ATOM   7103  C CA  . LYS B 1 256 ? 148.204 122.805 164.667 1.00 50.43  ?  245 LYS B CA  1 
ATOM   7104  C C   . LYS B 1 256 ? 147.716 121.410 164.988 1.00 50.43  ?  245 LYS B C   1 
ATOM   7105  O O   . LYS B 1 256 ? 148.149 120.807 165.965 1.00 50.43  ?  245 LYS B O   1 
ATOM   7106  C CB  . LYS B 1 256 ? 147.159 123.813 165.106 1.00 50.43  ?  245 LYS B CB  1 
ATOM   7107  C CG  . LYS B 1 256 ? 147.462 125.256 164.754 1.00 50.43  ?  245 LYS B CG  1 
ATOM   7108  C CD  . LYS B 1 256 ? 146.244 126.121 165.027 1.00 50.43  ?  245 LYS B CD  1 
ATOM   7109  C CE  . LYS B 1 256 ? 146.502 127.576 164.684 1.00 50.43  ?  245 LYS B CE  1 
ATOM   7110  N NZ  . LYS B 1 256 ? 145.266 128.395 164.813 1.00 50.43  1  245 LYS B NZ  1 
ATOM   7111  N N   . VAL B 1 257 ? 146.821 120.889 164.159 1.00 50.41  ?  246 VAL B N   1 
ATOM   7112  C CA  . VAL B 1 257 ? 146.298 119.548 164.369 1.00 50.41  ?  246 VAL B CA  1 
ATOM   7113  C C   . VAL B 1 257 ? 147.396 118.505 164.230 1.00 50.41  ?  246 VAL B C   1 
ATOM   7114  O O   . VAL B 1 257 ? 147.476 117.580 165.030 1.00 50.41  ?  246 VAL B O   1 
ATOM   7115  C CB  . VAL B 1 257 ? 145.137 119.232 163.395 1.00 50.41  ?  246 VAL B CB  1 
ATOM   7116  C CG1 . VAL B 1 257 ? 144.735 117.770 163.500 1.00 50.41  ?  246 VAL B CG1 1 
ATOM   7117  C CG2 . VAL B 1 257 ? 143.954 120.144 163.666 1.00 50.41  ?  246 VAL B CG2 1 
ATOM   7118  N N   . LEU B 1 258 ? 148.250 118.662 163.227 1.00 51.62  ?  247 LEU B N   1 
ATOM   7119  C CA  . LEU B 1 258 ? 149.332 117.714 163.016 1.00 51.62  ?  247 LEU B CA  1 
ATOM   7120  C C   . LEU B 1 258 ? 150.282 117.695 164.199 1.00 51.62  ?  247 LEU B C   1 
ATOM   7121  O O   . LEU B 1 258 ? 150.759 116.638 164.598 1.00 51.62  ?  247 LEU B O   1 
ATOM   7122  C CB  . LEU B 1 258 ? 150.095 118.054 161.737 1.00 51.62  ?  247 LEU B CB  1 
ATOM   7123  C CG  . LEU B 1 258 ? 149.463 117.622 160.420 1.00 51.62  ?  247 LEU B CG  1 
ATOM   7124  C CD1 . LEU B 1 258 ? 150.201 118.249 159.249 1.00 51.62  ?  247 LEU B CD1 1 
ATOM   7125  C CD2 . LEU B 1 258 ? 149.470 116.108 160.316 1.00 51.62  ?  247 LEU B CD2 1 
ATOM   7126  N N   . TYR B 1 259 ? 150.566 118.862 164.760 1.00 54.39  ?  248 TYR B N   1 
ATOM   7127  C CA  . TYR B 1 259 ? 151.437 118.933 165.917 1.00 54.39  ?  248 TYR B CA  1 
ATOM   7128  C C   . TYR B 1 259 ? 150.804 118.249 167.108 1.00 54.39  ?  248 TYR B C   1 
ATOM   7129  O O   . TYR B 1 259 ? 151.452 117.471 167.790 1.00 54.39  ?  248 TYR B O   1 
ATOM   7130  C CB  . TYR B 1 259 ? 151.746 120.385 166.275 1.00 54.39  ?  248 TYR B CB  1 
ATOM   7131  C CG  . TYR B 1 259 ? 152.577 120.508 167.526 1.00 54.39  ?  248 TYR B CG  1 
ATOM   7132  C CD1 . TYR B 1 259 ? 151.980 120.701 168.763 1.00 54.39  ?  248 TYR B CD1 1 
ATOM   7133  C CD2 . TYR B 1 259 ? 153.958 120.407 167.473 1.00 54.39  ?  248 TYR B CD2 1 
ATOM   7134  C CE1 . TYR B 1 259 ? 152.738 120.803 169.911 1.00 54.39  ?  248 TYR B CE1 1 
ATOM   7135  C CE2 . TYR B 1 259 ? 154.725 120.507 168.616 1.00 54.39  ?  248 TYR B CE2 1 
ATOM   7136  C CZ  . TYR B 1 259 ? 154.109 120.705 169.830 1.00 54.39  ?  248 TYR B CZ  1 
ATOM   7137  O OH  . TYR B 1 259 ? 154.870 120.806 170.972 1.00 54.39  ?  248 TYR B OH  1 
ATOM   7138  N N   . SER B 1 260 ? 149.537 118.538 167.359 1.00 53.97  ?  249 SER B N   1 
ATOM   7139  C CA  . SER B 1 260 ? 148.853 117.937 168.482 1.00 53.97  ?  249 SER B CA  1 
ATOM   7140  C C   . SER B 1 260 ? 148.889 116.428 168.354 1.00 53.97  ?  249 SER B C   1 
ATOM   7141  O O   . SER B 1 260 ? 149.097 115.724 169.334 1.00 53.97  ?  249 SER B O   1 
ATOM   7142  C CB  . SER B 1 260 ? 147.413 118.431 168.553 1.00 53.97  ?  249 SER B CB  1 
ATOM   7143  O OG  . SER B 1 260 ? 147.354 119.841 168.647 1.00 53.97  ?  249 SER B OG  1 
ATOM   7144  N N   . VAL B 1 261 ? 148.708 115.926 167.143 1.00 53.46  ?  250 VAL B N   1 
ATOM   7145  C CA  . VAL B 1 261 ? 148.683 114.490 166.941 1.00 53.46  ?  250 VAL B CA  1 
ATOM   7146  C C   . VAL B 1 261 ? 150.036 113.825 167.130 1.00 53.46  ?  250 VAL B C   1 
ATOM   7147  O O   . VAL B 1 261 ? 150.155 112.874 167.889 1.00 53.46  ?  250 VAL B O   1 
ATOM   7148  C CB  . VAL B 1 261 ? 148.155 114.142 165.534 1.00 53.46  ?  250 VAL B CB  1 
ATOM   7149  C CG1 . VAL B 1 261 ? 148.541 112.725 165.146 1.00 53.46  ?  250 VAL B CG1 1 
ATOM   7150  C CG2 . VAL B 1 261 ? 146.650 114.339 165.467 1.00 53.46  ?  250 VAL B CG2 1 
ATOM   7151  N N   . PHE B 1 262 ? 151.060 114.325 166.462 1.00 55.84  ?  251 PHE B N   1 
ATOM   7152  C CA  . PHE B 1 262 ? 152.358 113.655 166.522 1.00 55.84  ?  251 PHE B CA  1 
ATOM   7153  C C   . PHE B 1 262 ? 153.105 113.967 167.803 1.00 55.84  ?  251 PHE B C   1 
ATOM   7154  O O   . PHE B 1 262 ? 154.036 113.258 168.159 1.00 55.84  ?  251 PHE B O   1 
ATOM   7155  C CB  . PHE B 1 262 ? 153.162 113.977 165.265 1.00 55.84  ?  251 PHE B CB  1 
ATOM   7156  C CG  . PHE B 1 262 ? 152.583 113.363 164.028 1.00 55.84  ?  251 PHE B CG  1 
ATOM   7157  C CD1 . PHE B 1 262 ? 152.785 112.022 163.754 1.00 55.84  ?  251 PHE B CD1 1 
ATOM   7158  C CD2 . PHE B 1 262 ? 151.808 114.111 163.161 1.00 55.84  ?  251 PHE B CD2 1 
ATOM   7159  C CE1 . PHE B 1 262 ? 152.241 111.443 162.625 1.00 55.84  ?  251 PHE B CE1 1 
ATOM   7160  C CE2 . PHE B 1 262 ? 151.263 113.539 162.031 1.00 55.84  ?  251 PHE B CE2 1 
ATOM   7161  C CZ  . PHE B 1 262 ? 151.480 112.203 161.762 1.00 55.84  ?  251 PHE B CZ  1 
ATOM   7162  N N   . SER B 1 263 ? 152.705 115.018 168.499 1.00 57.53  ?  252 SER B N   1 
ATOM   7163  C CA  . SER B 1 263 ? 153.292 115.306 169.789 1.00 57.53  ?  252 SER B CA  1 
ATOM   7164  C C   . SER B 1 263 ? 152.842 114.244 170.770 1.00 57.53  ?  252 SER B C   1 
ATOM   7165  O O   . SER B 1 263 ? 153.610 113.823 171.629 1.00 57.53  ?  252 SER B O   1 
ATOM   7166  C CB  . SER B 1 263 ? 152.843 116.676 170.271 1.00 57.53  ?  252 SER B CB  1 
ATOM   7167  O OG  . SER B 1 263 ? 153.163 116.867 171.636 1.00 57.53  ?  252 SER B OG  1 
ATOM   7168  N N   . GLN B 1 264 ? 151.607 113.774 170.634 1.00 58.87  ?  253 GLN B N   1 
ATOM   7169  C CA  . GLN B 1 264 ? 151.084 112.739 171.515 1.00 58.87  ?  253 GLN B CA  1 
ATOM   7170  C C   . GLN B 1 264 ? 151.069 111.410 170.816 1.00 58.87  ?  253 GLN B C   1 
ATOM   7171  O O   . GLN B 1 264 ? 150.313 110.527 171.197 1.00 58.87  ?  253 GLN B O   1 
ATOM   7172  C CB  . GLN B 1 264 ? 149.650 113.056 171.906 1.00 58.87  ?  253 GLN B CB  1 
ATOM   7173  C CG  . GLN B 1 264 ? 149.330 114.524 172.093 1.00 58.87  ?  253 GLN B CG  1 
ATOM   7174  C CD  . GLN B 1 264 ? 147.837 114.771 172.126 1.00 58.87  ?  253 GLN B CD  1 
ATOM   7175  O OE1 . GLN B 1 264 ? 147.368 115.866 171.820 1.00 58.87  ?  253 GLN B OE1 1 
ATOM   7176  N NE2 . GLN B 1 264 ? 147.076 113.742 172.479 1.00 58.87  ?  253 GLN B NE2 1 
ATOM   7177  N N   . ILE B 1 265 ? 151.908 111.237 169.807 1.00 59.80  ?  254 ILE B N   1 
ATOM   7178  C CA  . ILE B 1 265 ? 151.858 110.015 169.009 1.00 59.80  ?  254 ILE B CA  1 
ATOM   7179  C C   . ILE B 1 265 ? 152.112 108.743 169.803 1.00 59.80  ?  254 ILE B C   1 
ATOM   7180  O O   . ILE B 1 265 ? 151.693 107.664 169.396 1.00 59.80  ?  254 ILE B O   1 
ATOM   7181  C CB  . ILE B 1 265 ? 152.848 110.081 167.831 1.00 59.80  ?  254 ILE B CB  1 
ATOM   7182  C CG1 . ILE B 1 265 ? 152.374 109.174 166.692 1.00 59.80  ?  254 ILE B CG1 1 
ATOM   7183  C CG2 . ILE B 1 265 ? 154.253 109.714 168.286 1.00 59.80  ?  254 ILE B CG2 1 
ATOM   7184  C CD1 . ILE B 1 265 ? 151.023 109.560 166.133 1.00 59.80  ?  254 ILE B CD1 1 
ATOM   7185  N N   . GLU B 1 266 ? 152.792 108.857 170.933 1.00 62.35  ?  255 GLU B N   1 
ATOM   7186  C CA  . GLU B 1 266 ? 153.121 107.680 171.733 1.00 62.35  ?  255 GLU B CA  1 
ATOM   7187  C C   . GLU B 1 266 ? 151.912 107.112 172.479 1.00 62.35  ?  255 GLU B C   1 
ATOM   7188  O O   . GLU B 1 266 ? 151.961 105.989 172.970 1.00 62.35  ?  255 GLU B O   1 
ATOM   7189  C CB  . GLU B 1 266 ? 154.245 108.011 172.720 1.00 62.35  ?  255 GLU B CB  1 
ATOM   7190  C CG  . GLU B 1 266 ? 153.850 108.990 173.816 1.00 62.35  ?  255 GLU B CG  1 
ATOM   7191  C CD  . GLU B 1 266 ? 153.637 110.402 173.306 1.00 62.35  ?  255 GLU B CD  1 
ATOM   7192  O OE1 . GLU B 1 266 ? 154.163 110.735 172.224 1.00 62.35  ?  255 GLU B OE1 1 
ATOM   7193  O OE2 . GLU B 1 266 ? 152.946 111.183 173.994 1.00 62.35  -1 255 GLU B OE2 1 
ATOM   7194  N N   . LYS B 1 267 ? 150.831 107.879 172.565 1.00 61.70  ?  256 LYS B N   1 
ATOM   7195  C CA  . LYS B 1 267 ? 149.624 107.408 173.235 1.00 61.70  ?  256 LYS B CA  1 
ATOM   7196  C C   . LYS B 1 267 ? 148.688 106.690 172.271 1.00 61.70  ?  256 LYS B C   1 
ATOM   7197  O O   . LYS B 1 267 ? 147.577 106.328 172.643 1.00 61.70  ?  256 LYS B O   1 
ATOM   7198  C CB  . LYS B 1 267 ? 148.886 108.579 173.874 1.00 61.70  ?  256 LYS B CB  1 
ATOM   7199  C CG  . LYS B 1 267 ? 149.784 109.619 174.517 1.00 61.70  ?  256 LYS B CG  1 
ATOM   7200  C CD  . LYS B 1 267 ? 148.973 110.839 174.920 1.00 61.70  ?  256 LYS B CD  1 
ATOM   7201  C CE  . LYS B 1 267 ? 149.865 111.959 175.426 1.00 61.70  ?  256 LYS B CE  1 
ATOM   7202  N NZ  . LYS B 1 267 ? 149.074 113.173 175.769 1.00 61.70  1  256 LYS B NZ  1 
ATOM   7203  N N   . THR B 1 268 ? 149.125 106.484 171.035 1.00 61.34  ?  257 THR B N   1 
ATOM   7204  C CA  . THR B 1 268 ? 148.277 105.846 170.033 1.00 61.34  ?  257 THR B CA  1 
ATOM   7205  C C   . THR B 1 268 ? 147.731 104.503 170.475 1.00 61.34  ?  257 THR B C   1 
ATOM   7206  O O   . THR B 1 268 ? 148.470 103.686 171.017 1.00 61.34  ?  257 THR B O   1 
ATOM   7207  C CB  . THR B 1 268 ? 149.032 105.639 168.703 1.00 61.34  ?  257 THR B CB  1 
ATOM   7208  O OG1 . THR B 1 268 ? 149.304 106.909 168.104 1.00 61.34  ?  257 THR B OG1 1 
ATOM   7209  C CG2 . THR B 1 268 ? 148.208 104.803 167.739 1.00 61.34  ?  257 THR B CG2 1 
ATOM   7210  N N   . ASN B 1 269 ? 146.442 104.273 170.256 1.00 63.20  ?  258 ASN B N   1 
ATOM   7211  C CA  . ASN B 1 269 ? 145.847 102.982 170.568 1.00 63.20  ?  258 ASN B CA  1 
ATOM   7212  C C   . ASN B 1 269 ? 146.105 102.068 169.396 1.00 63.20  ?  258 ASN B C   1 
ATOM   7213  O O   . ASN B 1 269 ? 145.596 102.300 168.305 1.00 63.20  ?  258 ASN B O   1 
ATOM   7214  C CB  . ASN B 1 269 ? 144.349 103.132 170.812 1.00 63.20  ?  258 ASN B CB  1 
ATOM   7215  C CG  . ASN B 1 269 ? 143.680 101.826 171.189 1.00 63.20  ?  258 ASN B CG  1 
ATOM   7216  O OD1 . ASN B 1 269 ? 143.897 100.795 170.557 1.00 63.20  ?  258 ASN B OD1 1 
ATOM   7217  N ND2 . ASN B 1 269 ? 142.841 101.871 172.216 1.00 63.20  ?  258 ASN B ND2 1 
ATOM   7218  N N   . ILE B 1 270 ? 146.894 101.026 169.603 1.00 64.63  ?  259 ILE B N   1 
ATOM   7219  C CA  . ILE B 1 270 ? 147.259 100.146 168.498 1.00 64.63  ?  259 ILE B CA  1 
ATOM   7220  C C   . ILE B 1 270 ? 146.059 99.441  167.870 1.00 64.63  ?  259 ILE B C   1 
ATOM   7221  O O   . ILE B 1 270 ? 145.981 99.329  166.654 1.00 64.63  ?  259 ILE B O   1 
ATOM   7222  C CB  . ILE B 1 270 ? 148.293 99.092  168.944 1.00 64.63  ?  259 ILE B CB  1 
ATOM   7223  C CG1 . ILE B 1 270 ? 149.468 99.772  169.645 1.00 64.63  ?  259 ILE B CG1 1 
ATOM   7224  C CG2 . ILE B 1 270 ? 148.770 98.273  167.756 1.00 64.63  ?  259 ILE B CG2 1 
ATOM   7225  C CD1 . ILE B 1 270 ? 150.125 100.854 168.817 1.00 64.63  ?  259 ILE B CD1 1 
ATOM   7226  N N   . ALA B 1 271 ? 145.127 98.975  168.692 1.00 63.81  ?  260 ALA B N   1 
ATOM   7227  C CA  . ALA B 1 271 ? 143.973 98.259  168.174 1.00 63.81  ?  260 ALA B CA  1 
ATOM   7228  C C   . ALA B 1 271 ? 143.211 99.121  167.185 1.00 63.81  ?  260 ALA B C   1 
ATOM   7229  O O   . ALA B 1 271 ? 142.862 98.663  166.103 1.00 63.81  ?  260 ALA B O   1 
ATOM   7230  C CB  . ALA B 1 271 ? 143.070 97.824  169.310 1.00 63.81  ?  260 ALA B CB  1 
ATOM   7231  N N   . ASP B 1 272 ? 142.981 100.376 167.537 1.00 63.12  ?  261 ASP B N   1 
ATOM   7232  C CA  . ASP B 1 272 ? 142.308 101.288 166.629 1.00 63.12  ?  261 ASP B CA  1 
ATOM   7233  C C   . ASP B 1 272 ? 143.080 101.430 165.337 1.00 63.12  ?  261 ASP B C   1 
ATOM   7234  O O   . ASP B 1 272 ? 142.506 101.333 164.259 1.00 63.12  ?  261 ASP B O   1 
ATOM   7235  C CB  . ASP B 1 272 ? 142.160 102.660 167.280 1.00 63.12  ?  261 ASP B CB  1 
ATOM   7236  C CG  . ASP B 1 272 ? 141.043 102.707 168.294 1.00 63.12  ?  261 ASP B CG  1 
ATOM   7237  O OD1 . ASP B 1 272 ? 140.174 101.819 168.261 1.00 63.12  ?  261 ASP B OD1 1 
ATOM   7238  O OD2 . ASP B 1 272 ? 141.027 103.641 169.120 1.00 63.12  -1 261 ASP B OD2 1 
ATOM   7239  N N   . LEU B 1 273 ? 144.384 101.652 165.440 1.00 62.41  ?  262 LEU B N   1 
ATOM   7240  C CA  . LEU B 1 273 ? 145.215 101.841 164.257 1.00 62.41  ?  262 LEU B CA  1 
ATOM   7241  C C   . LEU B 1 273 ? 145.226 100.617 163.357 1.00 62.41  ?  262 LEU B C   1 
ATOM   7242  O O   . LEU B 1 273 ? 145.041 100.730 162.152 1.00 62.41  ?  262 LEU B O   1 
ATOM   7243  C CB  . LEU B 1 273 ? 146.640 102.203 164.666 1.00 62.41  ?  262 LEU B CB  1 
ATOM   7244  C CG  . LEU B 1 273 ? 147.662 102.313 163.537 1.00 62.41  ?  262 LEU B CG  1 
ATOM   7245  C CD1 . LEU B 1 273 ? 147.277 103.423 162.574 1.00 62.41  ?  262 LEU B CD1 1 
ATOM   7246  C CD2 . LEU B 1 273 ? 149.051 102.552 164.103 1.00 62.41  ?  262 LEU B CD2 1 
ATOM   7247  N N   . VAL B 1 274 ? 145.434 99.446  163.939 1.00 62.54  ?  263 VAL B N   1 
ATOM   7248  C CA  . VAL B 1 274 ? 145.430 98.226  163.152 1.00 62.54  ?  263 VAL B CA  1 
ATOM   7249  C C   . VAL B 1 274 ? 144.077 98.099  162.494 1.00 62.54  ?  263 VAL B C   1 
ATOM   7250  O O   . VAL B 1 274 ? 143.989 97.859  161.296 1.00 62.54  ?  263 VAL B O   1 
ATOM   7251  C CB  . VAL B 1 274 ? 145.727 96.988  164.011 1.00 62.54  ?  263 VAL B CB  1 
ATOM   7252  C CG1 . VAL B 1 274 ? 145.712 95.732  163.156 1.00 62.54  ?  263 VAL B CG1 1 
ATOM   7253  C CG2 . VAL B 1 274 ? 147.068 97.143  164.707 1.00 62.54  ?  263 VAL B CG2 1 
ATOM   7254  N N   . THR B 1 275 ? 143.015 98.273  163.266 1.00 63.25  ?  264 THR B N   1 
ATOM   7255  C CA  . THR B 1 275 ? 141.685 98.262  162.691 1.00 63.25  ?  264 THR B CA  1 
ATOM   7256  C C   . THR B 1 275 ? 141.602 99.304  161.573 1.00 63.25  ?  264 THR B C   1 
ATOM   7257  O O   . THR B 1 275 ? 141.307 98.958  160.437 1.00 63.25  ?  264 THR B O   1 
ATOM   7258  C CB  . THR B 1 275 ? 140.605 98.544  163.747 1.00 63.25  ?  264 THR B CB  1 
ATOM   7259  O OG1 . THR B 1 275 ? 140.764 97.643  164.849 1.00 63.25  ?  264 THR B OG1 1 
ATOM   7260  C CG2 . THR B 1 275 ? 139.220 98.367  163.147 1.00 63.25  ?  264 THR B CG2 1 
ATOM   7261  N N   . ALA B 1 276 ? 141.873 100.574 161.879 1.00 62.22  ?  265 ALA B N   1 
ATOM   7262  C CA  . ALA B 1 276 ? 141.723 101.566 160.826 1.00 62.22  ?  265 ALA B CA  1 
ATOM   7263  C C   . ALA B 1 276 ? 142.544 101.197 159.603 1.00 62.22  ?  265 ALA B C   1 
ATOM   7264  O O   . ALA B 1 276 ? 142.083 101.355 158.470 1.00 62.22  ?  265 ALA B O   1 
ATOM   7265  C CB  . ALA B 1 276 ? 142.129 102.942 161.344 1.00 62.22  ?  265 ALA B CB  1 
ATOM   7266  N N   . LEU B 1 277 ? 143.757 100.685 159.810 1.00 63.32  ?  266 LEU B N   1 
ATOM   7267  C CA  . LEU B 1 277 ? 144.591 100.313 158.672 1.00 63.32  ?  266 LEU B CA  1 
ATOM   7268  C C   . LEU B 1 277 ? 144.007 99.120  157.929 1.00 63.32  ?  266 LEU B C   1 
ATOM   7269  O O   . LEU B 1 277 ? 144.018 99.091  156.695 1.00 63.32  ?  266 LEU B O   1 
ATOM   7270  C CB  . LEU B 1 277 ? 146.016 100.019 159.133 1.00 63.32  ?  266 LEU B CB  1 
ATOM   7271  C CG  . LEU B 1 277 ? 146.806 101.219 159.656 1.00 63.32  ?  266 LEU B CG  1 
ATOM   7272  C CD1 . LEU B 1 277 ? 148.269 100.860 159.818 1.00 63.32  ?  266 LEU B CD1 1 
ATOM   7273  C CD2 . LEU B 1 277 ? 146.645 102.419 158.742 1.00 63.32  ?  266 LEU B CD2 1 
ATOM   7274  N N   . ILE B 1 278 ? 143.470 98.140  158.658 1.00 63.41  ?  267 ILE B N   1 
ATOM   7275  C CA  . ILE B 1 278 ? 142.869 96.979  158.004 1.00 63.41  ?  267 ILE B CA  1 
ATOM   7276  C C   . ILE B 1 278 ? 141.639 97.394  157.205 1.00 63.41  ?  267 ILE B C   1 
ATOM   7277  O O   . ILE B 1 278 ? 141.458 96.985  156.049 1.00 63.41  ?  267 ILE B O   1 
ATOM   7278  C CB  . ILE B 1 278 ? 142.529 95.895  159.040 1.00 63.41  ?  267 ILE B CB  1 
ATOM   7279  C CG1 . ILE B 1 278 ? 143.811 95.314  159.635 1.00 63.41  ?  267 ILE B CG1 1 
ATOM   7280  C CG2 . ILE B 1 278 ? 141.698 94.801  158.407 1.00 63.41  ?  267 ILE B CG2 1 
ATOM   7281  C CD1 . ILE B 1 278 ? 143.570 94.229  160.650 1.00 63.41  ?  267 ILE B CD1 1 
ATOM   7282  N N   . VAL B 1 279 ? 140.777 98.218  157.806 1.00 63.77  ?  268 VAL B N   1 
ATOM   7283  C CA  . VAL B 1 279 ? 139.573 98.661  157.110 1.00 63.77  ?  268 VAL B CA  1 
ATOM   7284  C C   . VAL B 1 279 ? 139.938 99.483  155.882 1.00 63.77  ?  268 VAL B C   1 
ATOM   7285  O O   . VAL B 1 279 ? 139.367 99.294  154.804 1.00 63.77  ?  268 VAL B O   1 
ATOM   7286  C CB  . VAL B 1 279 ? 138.656 99.443  158.070 1.00 63.77  ?  268 VAL B CB  1 
ATOM   7287  C CG1 . VAL B 1 279 ? 137.558 100.143 157.300 1.00 63.77  ?  268 VAL B CG1 1 
ATOM   7288  C CG2 . VAL B 1 279 ? 138.055 98.509  159.095 1.00 63.77  ?  268 VAL B CG2 1 
ATOM   7289  N N   . LEU B 1 280 ? 140.904 100.393 156.017 1.00 64.98  ?  269 LEU B N   1 
ATOM   7290  C CA  . LEU B 1 280 ? 141.327 101.219 154.892 1.00 64.98  ?  269 LEU B CA  1 
ATOM   7291  C C   . LEU B 1 280 ? 141.896 100.367 153.763 1.00 64.98  ?  269 LEU B C   1 
ATOM   7292  O O   . LEU B 1 280 ? 141.556 100.564 152.591 1.00 64.98  ?  269 LEU B O   1 
ATOM   7293  C CB  . LEU B 1 280 ? 142.356 102.244 155.372 1.00 64.98  ?  269 LEU B CB  1 
ATOM   7294  C CG  . LEU B 1 280 ? 142.839 103.348 154.436 1.00 64.98  ?  269 LEU B CG  1 
ATOM   7295  C CD1 . LEU B 1 280 ? 141.745 103.779 153.491 1.00 64.98  ?  269 LEU B CD1 1 
ATOM   7296  C CD2 . LEU B 1 280 ? 143.319 104.522 155.255 1.00 64.98  ?  269 LEU B CD2 1 
ATOM   7297  N N   . LEU B 1 281 ? 142.753 99.402  154.102 1.00 67.98  ?  270 LEU B N   1 
ATOM   7298  C CA  . LEU B 1 281 ? 143.349 98.544  153.086 1.00 67.98  ?  270 LEU B CA  1 
ATOM   7299  C C   . LEU B 1 281 ? 142.287 97.753  152.337 1.00 67.98  ?  270 LEU B C   1 
ATOM   7300  O O   . LEU B 1 281 ? 142.255 97.750  151.100 1.00 67.98  ?  270 LEU B O   1 
ATOM   7301  C CB  . LEU B 1 281 ? 144.362 97.603  153.733 1.00 67.98  ?  270 LEU B CB  1 
ATOM   7302  C CG  . LEU B 1 281 ? 144.853 96.451  152.858 1.00 67.98  ?  270 LEU B CG  1 
ATOM   7303  C CD1 . LEU B 1 281 ? 145.767 96.979  151.770 1.00 67.98  ?  270 LEU B CD1 1 
ATOM   7304  C CD2 . LEU B 1 281 ? 145.561 95.408  153.701 1.00 67.98  ?  270 LEU B CD2 1 
ATOM   7305  N N   . VAL B 1 282 ? 141.441 97.008  153.037 1.00 67.82  ?  271 VAL B N   1 
ATOM   7306  C CA  . VAL B 1 282 ? 140.467 96.144  152.356 1.00 67.82  ?  271 VAL B CA  1 
ATOM   7307  C C   . VAL B 1 282 ? 139.519 96.894  151.431 1.00 67.82  ?  271 VAL B C   1 
ATOM   7308  O O   . VAL B 1 282 ? 139.312 96.495  150.287 1.00 67.82  ?  271 VAL B O   1 
ATOM   7309  C CB  . VAL B 1 282 ? 139.627 95.341  153.365 1.00 67.82  ?  271 VAL B CB  1 
ATOM   7310  C CG1 . VAL B 1 282 ? 138.483 94.626  152.663 1.00 67.82  ?  271 VAL B CG1 1 
ATOM   7311  C CG2 . VAL B 1 282 ? 140.503 94.357  154.122 1.00 67.82  ?  271 VAL B CG2 1 
ATOM   7312  N N   . VAL B 1 283 ? 138.944 97.981  151.916 1.00 69.64  ?  272 VAL B N   1 
ATOM   7313  C CA  . VAL B 1 283 ? 137.994 98.728  151.112 1.00 69.64  ?  272 VAL B CA  1 
ATOM   7314  C C   . VAL B 1 283 ? 138.644 99.203  149.828 1.00 69.64  ?  272 VAL B C   1 
ATOM   7315  O O   . VAL B 1 283 ? 138.033 99.150  148.764 1.00 69.64  ?  272 VAL B O   1 
ATOM   7316  C CB  . VAL B 1 283 ? 137.431 99.923  151.898 1.00 69.64  ?  272 VAL B CB  1 
ATOM   7317  C CG1 . VAL B 1 283 ? 136.665 100.858 150.981 1.00 69.64  ?  272 VAL B CG1 1 
ATOM   7318  C CG2 . VAL B 1 283 ? 136.551 99.437  153.037 1.00 69.64  ?  272 VAL B CG2 1 
ATOM   7319  N N   . SER B 1 284 ? 139.886 99.648  149.915 1.00 72.20  ?  273 SER B N   1 
ATOM   7320  C CA  . SER B 1 284 ? 140.591 100.151 148.740 1.00 72.20  ?  273 SER B CA  1 
ATOM   7321  C C   . SER B 1 284 ? 140.662 99.112  147.631 1.00 72.20  ?  273 SER B C   1 
ATOM   7322  O O   . SER B 1 284 ? 140.332 99.402  146.479 1.00 72.20  ?  273 SER B O   1 
ATOM   7323  C CB  . SER B 1 284 ? 142.000 100.587 149.127 1.00 72.20  ?  273 SER B CB  1 
ATOM   7324  O OG  . SER B 1 284 ? 141.965 101.580 150.136 1.00 72.20  ?  273 SER B OG  1 
ATOM   7325  N N   . ILE B 1 285 ? 141.066 97.899  147.976 1.00 74.22  ?  274 ILE B N   1 
ATOM   7326  C CA  . ILE B 1 285 ? 141.156 96.843  146.983 1.00 74.22  ?  274 ILE B CA  1 
ATOM   7327  C C   . ILE B 1 285 ? 139.796 96.535  146.373 1.00 74.22  ?  274 ILE B C   1 
ATOM   7328  O O   . ILE B 1 285 ? 139.667 96.419  145.159 1.00 74.22  ?  274 ILE B O   1 
ATOM   7329  C CB  . ILE B 1 285 ? 141.730 95.553  147.588 1.00 74.22  ?  274 ILE B CB  1 
ATOM   7330  C CG1 . ILE B 1 285 ? 143.053 95.849  148.295 1.00 74.22  ?  274 ILE B CG1 1 
ATOM   7331  C CG2 . ILE B 1 285 ? 141.909 94.496  146.511 1.00 74.22  ?  274 ILE B CG2 1 
ATOM   7332  C CD1 . ILE B 1 285 ? 143.638 94.653  149.014 1.00 74.22  ?  274 ILE B CD1 1 
ATOM   7333  N N   . VAL B 1 286 ? 138.775 96.410  147.208 1.00 75.54  ?  275 VAL B N   1 
ATOM   7334  C CA  . VAL B 1 286 ? 137.460 96.050  146.696 1.00 75.54  ?  275 VAL B CA  1 
ATOM   7335  C C   . VAL B 1 286 ? 136.912 97.141  145.786 1.00 75.54  ?  275 VAL B C   1 
ATOM   7336  O O   . VAL B 1 286 ? 136.258 96.854  144.791 1.00 75.54  ?  275 VAL B O   1 
ATOM   7337  C CB  . VAL B 1 286 ? 136.474 95.753  147.837 1.00 75.54  ?  275 VAL B CB  1 
ATOM   7338  C CG1 . VAL B 1 286 ? 135.090 95.460  147.280 1.00 75.54  ?  275 VAL B CG1 1 
ATOM   7339  C CG2 . VAL B 1 286 ? 136.976 94.589  148.672 1.00 75.54  ?  275 VAL B CG2 1 
ATOM   7340  N N   . LYS B 1 287 ? 137.178 98.394  146.124 1.00 76.00  ?  276 LYS B N   1 
ATOM   7341  C CA  . LYS B 1 287 ? 136.693 99.498  145.313 1.00 76.00  ?  276 LYS B CA  1 
ATOM   7342  C C   . LYS B 1 287 ? 137.305 99.478  143.917 1.00 76.00  ?  276 LYS B C   1 
ATOM   7343  O O   . LYS B 1 287 ? 136.624 99.761  142.934 1.00 76.00  ?  276 LYS B O   1 
ATOM   7344  C CB  . LYS B 1 287 ? 136.975 100.836 145.999 1.00 76.00  ?  276 LYS B CB  1 
ATOM   7345  C CG  . LYS B 1 287 ? 136.058 101.141 147.170 1.00 76.00  ?  276 LYS B CG  1 
ATOM   7346  C CD  . LYS B 1 287 ? 136.310 102.540 147.707 1.00 76.00  ?  276 LYS B CD  1 
ATOM   7347  C CE  . LYS B 1 287 ? 135.256 102.944 148.725 1.00 76.00  ?  276 LYS B CE  1 
ATOM   7348  N NZ  . LYS B 1 287 ? 133.882 102.880 148.156 1.00 76.00  1  276 LYS B NZ  1 
ATOM   7349  N N   . GLU B 1 288 ? 138.587 99.145  143.825 1.00 82.67  ?  277 GLU B N   1 
ATOM   7350  C CA  . GLU B 1 288 ? 139.236 99.068  142.526 1.00 82.67  ?  277 GLU B CA  1 
ATOM   7351  C C   . GLU B 1 288 ? 138.658 97.910  141.735 1.00 82.67  ?  277 GLU B C   1 
ATOM   7352  O O   . GLU B 1 288 ? 138.485 98.012  140.525 1.00 82.67  ?  277 GLU B O   1 
ATOM   7353  C CB  . GLU B 1 288 ? 140.752 98.932  142.670 1.00 82.67  ?  277 GLU B CB  1 
ATOM   7354  C CG  . GLU B 1 288 ? 141.231 97.551  143.080 1.00 82.67  ?  277 GLU B CG  1 
ATOM   7355  C CD  . GLU B 1 288 ? 142.740 97.465  143.190 1.00 82.67  ?  277 GLU B CD  1 
ATOM   7356  O OE1 . GLU B 1 288 ? 143.417 98.459  142.860 1.00 82.67  ?  277 GLU B OE1 1 
ATOM   7357  O OE2 . GLU B 1 288 ? 143.247 96.400  143.603 1.00 82.67  -1 277 GLU B OE2 1 
ATOM   7358  N N   . ILE B 1 289 ? 138.354 96.809  142.408 1.00 82.16  ?  278 ILE B N   1 
ATOM   7359  C CA  . ILE B 1 289 ? 137.726 95.688  141.732 1.00 82.16  ?  278 ILE B CA  1 
ATOM   7360  C C   . ILE B 1 289 ? 136.386 96.133  141.179 1.00 82.16  ?  278 ILE B C   1 
ATOM   7361  O O   . ILE B 1 289 ? 136.017 95.779  140.063 1.00 82.16  ?  278 ILE B O   1 
ATOM   7362  C CB  . ILE B 1 289 ? 137.519 94.511  142.690 1.00 82.16  ?  278 ILE B CB  1 
ATOM   7363  C CG1 . ILE B 1 289 ? 138.868 93.993  143.189 1.00 82.16  ?  278 ILE B CG1 1 
ATOM   7364  C CG2 . ILE B 1 289 ? 136.733 93.400  142.013 1.00 82.16  ?  278 ILE B CG2 1 
ATOM   7365  C CD1 . ILE B 1 289 ? 138.751 92.934  144.260 1.00 82.16  ?  278 ILE B CD1 1 
ATOM   7366  N N   . ASN B 1 290 ? 135.658 96.924  141.953 1.00 83.20  ?  279 ASN B N   1 
ATOM   7367  C CA  . ASN B 1 290 ? 134.362 97.415  141.509 1.00 83.20  ?  279 ASN B CA  1 
ATOM   7368  C C   . ASN B 1 290 ? 134.497 98.345  140.313 1.00 83.20  ?  279 ASN B C   1 
ATOM   7369  O O   . ASN B 1 290 ? 133.586 98.448  139.500 1.00 83.20  ?  279 ASN B O   1 
ATOM   7370  C CB  . ASN B 1 290 ? 133.634 98.121  142.655 1.00 83.20  ?  279 ASN B CB  1 
ATOM   7371  C CG  . ASN B 1 290 ? 133.241 97.174  143.768 1.00 83.20  ?  279 ASN B CG  1 
ATOM   7372  O OD1 . ASN B 1 290 ? 133.430 95.962  143.663 1.00 83.20  ?  279 ASN B OD1 1 
ATOM   7373  N ND2 . ASN B 1 290 ? 132.690 97.721  144.842 1.00 83.20  ?  279 ASN B ND2 1 
ATOM   7374  N N   . GLN B 1 291 ? 135.625 99.035  140.215 1.00 87.89  ?  280 GLN B N   1 
ATOM   7375  C CA  . GLN B 1 291 ? 135.847 99.948  139.099 1.00 87.89  ?  280 GLN B CA  1 
ATOM   7376  C C   . GLN B 1 291 ? 136.441 99.232  137.887 1.00 87.89  ?  280 GLN B C   1 
ATOM   7377  O O   . GLN B 1 291 ? 136.363 99.731  136.770 1.00 87.89  ?  280 GLN B O   1 
ATOM   7378  C CB  . GLN B 1 291 ? 136.749 101.105 139.533 1.00 87.89  ?  280 GLN B CB  1 
ATOM   7379  C CG  . GLN B 1 291 ? 137.098 102.083 138.425 1.00 87.89  ?  280 GLN B CG  1 
ATOM   7380  C CD  . GLN B 1 291 ? 135.875 102.726 137.803 1.00 87.89  ?  280 GLN B CD  1 
ATOM   7381  O OE1 . GLN B 1 291 ? 134.800 102.762 138.404 1.00 87.89  ?  280 GLN B OE1 1 
ATOM   7382  N NE2 . GLN B 1 291 ? 136.034 103.248 136.592 1.00 87.89  ?  280 GLN B NE2 1 
ATOM   7383  N N   . ARG B 1 292 ? 137.021 98.060  138.108 1.00 89.03  ?  281 ARG B N   1 
ATOM   7384  C CA  . ARG B 1 292 ? 137.604 97.302  137.012 1.00 89.03  ?  281 ARG B CA  1 
ATOM   7385  C C   . ARG B 1 292 ? 136.616 96.304  136.440 1.00 89.03  ?  281 ARG B C   1 
ATOM   7386  O O   . ARG B 1 292 ? 136.285 96.359  135.257 1.00 89.03  ?  281 ARG B O   1 
ATOM   7387  C CB  . ARG B 1 292 ? 138.855 96.565  137.482 1.00 89.03  ?  281 ARG B CB  1 
ATOM   7388  C CG  . ARG B 1 292 ? 140.066 97.462  137.666 1.00 89.03  ?  281 ARG B CG  1 
ATOM   7389  C CD  . ARG B 1 292 ? 141.301 96.647  138.009 1.00 89.03  ?  281 ARG B CD  1 
ATOM   7390  N NE  . ARG B 1 292 ? 142.525 97.434  137.891 1.00 89.03  ?  281 ARG B NE  1 
ATOM   7391  C CZ  . ARG B 1 292 ? 143.053 98.147  138.879 1.00 89.03  ?  281 ARG B CZ  1 
ATOM   7392  N NH1 . ARG B 1 292 ? 142.464 98.176  140.066 1.00 89.03  1  281 ARG B NH1 1 
ATOM   7393  N NH2 . ARG B 1 292 ? 144.171 98.832  138.681 1.00 89.03  ?  281 ARG B NH2 1 
ATOM   7394  N N   . PHE B 1 293 ? 136.147 95.387  137.271 1.00 89.92  ?  282 PHE B N   1 
ATOM   7395  C CA  . PHE B 1 293 ? 135.212 94.378  136.812 1.00 89.92  ?  282 PHE B CA  1 
ATOM   7396  C C   . PHE B 1 293 ? 133.807 94.931  136.877 1.00 89.92  ?  282 PHE B C   1 
ATOM   7397  O O   . PHE B 1 293 ? 132.852 94.185  137.060 1.00 89.92  ?  282 PHE B O   1 
ATOM   7398  C CB  . PHE B 1 293 ? 135.328 93.127  137.670 1.00 89.92  ?  282 PHE B CB  1 
ATOM   7399  C CG  . PHE B 1 293 ? 136.734 92.628  137.813 1.00 89.92  ?  282 PHE B CG  1 
ATOM   7400  C CD1 . PHE B 1 293 ? 137.576 93.162  138.772 1.00 89.92  ?  282 PHE B CD1 1 
ATOM   7401  C CD2 . PHE B 1 293 ? 137.214 91.631  136.985 1.00 89.92  ?  282 PHE B CD2 1 
ATOM   7402  C CE1 . PHE B 1 293 ? 138.873 92.709  138.907 1.00 89.92  ?  282 PHE B CE1 1 
ATOM   7403  C CE2 . PHE B 1 293 ? 138.510 91.171  137.114 1.00 89.92  ?  282 PHE B CE2 1 
ATOM   7404  C CZ  . PHE B 1 293 ? 139.340 91.711  138.076 1.00 89.92  ?  282 PHE B CZ  1 
ATOM   7405  N N   . LYS B 1 294 ? 133.736 96.246  136.694 1.00 90.16  ?  283 LYS B N   1 
ATOM   7406  C CA  . LYS B 1 294 ? 132.511 97.026  136.726 1.00 90.16  ?  283 LYS B CA  1 
ATOM   7407  C C   . LYS B 1 294 ? 131.374 96.455  135.914 1.00 90.16  ?  283 LYS B C   1 
ATOM   7408  O O   . LYS B 1 294 ? 130.344 96.087  136.457 1.00 90.16  ?  283 LYS B O   1 
ATOM   7409  C CB  . LYS B 1 294 ? 132.782 98.448  136.247 1.00 90.16  ?  283 LYS B CB  1 
ATOM   7410  C CG  . LYS B 1 294 ? 131.538 99.307  136.196 1.00 90.16  ?  283 LYS B CG  1 
ATOM   7411  C CD  . LYS B 1 294 ? 131.890 100.780 136.274 1.00 90.16  ?  283 LYS B CD  1 
ATOM   7412  C CE  . LYS B 1 294 ? 130.794 101.552 136.990 1.00 90.16  ?  283 LYS B CE  1 
ATOM   7413  N NZ  . LYS B 1 294 ? 131.112 102.999 137.119 1.00 90.16  1  283 LYS B NZ  1 
ATOM   7414  N N   . ASP B 1 295 ? 131.552 96.408  134.603 1.00 93.76  ?  284 ASP B N   1 
ATOM   7415  C CA  . ASP B 1 295 ? 130.523 95.885  133.715 1.00 93.76  ?  284 ASP B CA  1 
ATOM   7416  C C   . ASP B 1 295 ? 130.242 94.413  133.983 1.00 93.76  ?  284 ASP B C   1 
ATOM   7417  O O   . ASP B 1 295 ? 129.105 93.976  133.893 1.00 93.76  ?  284 ASP B O   1 
ATOM   7418  C CB  . ASP B 1 295 ? 130.863 96.154  132.253 1.00 93.76  ?  284 ASP B CB  1 
ATOM   7419  C CG  . ASP B 1 295 ? 130.611 97.596  131.863 1.00 93.76  ?  284 ASP B CG  1 
ATOM   7420  O OD1 . ASP B 1 295 ? 130.532 98.456  132.763 1.00 93.76  ?  284 ASP B OD1 1 
ATOM   7421  O OD2 . ASP B 1 295 ? 130.490 97.876  130.654 1.00 93.76  -1 284 ASP B OD2 1 
ATOM   7422  N N   . LYS B 1 296 ? 131.281 93.644  134.287 1.00 94.68  ?  285 LYS B N   1 
ATOM   7423  C CA  . LYS B 1 296 ? 131.099 92.237  134.597 1.00 94.68  ?  285 LYS B CA  1 
ATOM   7424  C C   . LYS B 1 296 ? 130.240 92.081  135.851 1.00 94.68  ?  285 LYS B C   1 
ATOM   7425  O O   . LYS B 1 296 ? 129.366 91.230  135.902 1.00 94.68  ?  285 LYS B O   1 
ATOM   7426  C CB  . LYS B 1 296 ? 132.449 91.551  134.799 1.00 94.68  ?  285 LYS B CB  1 
ATOM   7427  N N   . LEU B 1 297 ? 130.488 92.919  136.855 1.00 90.80  ?  286 LEU B N   1 
ATOM   7428  C CA  . LEU B 1 297 ? 129.743 92.885  138.116 1.00 90.80  ?  286 LEU B CA  1 
ATOM   7429  C C   . LEU B 1 297 ? 128.300 93.317  137.929 1.00 90.80  ?  286 LEU B C   1 
ATOM   7430  O O   . LEU B 1 297 ? 128.021 94.294  137.245 1.00 90.80  ?  286 LEU B O   1 
ATOM   7431  C CB  . LEU B 1 297 ? 130.405 93.782  139.160 1.00 90.80  ?  286 LEU B CB  1 
ATOM   7432  C CG  . LEU B 1 297 ? 131.636 93.246  139.885 1.00 90.80  ?  286 LEU B CG  1 
ATOM   7433  C CD1 . LEU B 1 297 ? 132.369 94.383  140.570 1.00 90.80  ?  286 LEU B CD1 1 
ATOM   7434  C CD2 . LEU B 1 297 ? 131.267 92.155  140.875 1.00 90.80  ?  286 LEU B CD2 1 
ATOM   7435  N N   . PRO B 1 298 ? 127.374 92.586  138.550 1.00 88.55  ?  287 PRO B N   1 
ATOM   7436  C CA  . PRO B 1 298 ? 125.960 92.935  138.414 1.00 88.55  ?  287 PRO B CA  1 
ATOM   7437  C C   . PRO B 1 298 ? 125.675 94.149  139.261 1.00 88.55  ?  287 PRO B C   1 
ATOM   7438  O O   . PRO B 1 298 ? 124.993 95.068  138.813 1.00 88.55  ?  287 PRO B O   1 
ATOM   7439  C CB  . PRO B 1 298 ? 125.245 91.716  138.991 1.00 88.55  ?  287 PRO B CB  1 
ATOM   7440  C CG  . PRO B 1 298 ? 126.240 91.072  139.896 1.00 88.55  ?  287 PRO B CG  1 
ATOM   7441  C CD  . PRO B 1 298 ? 127.574 91.310  139.255 1.00 88.55  ?  287 PRO B CD  1 
ATOM   7442  N N   . VAL B 1 299 ? 126.195 94.159  140.480 1.00 85.46  ?  288 VAL B N   1 
ATOM   7443  C CA  . VAL B 1 299 ? 126.018 95.290  141.368 1.00 85.46  ?  288 VAL B CA  1 
ATOM   7444  C C   . VAL B 1 299 ? 127.360 95.542  142.010 1.00 85.46  ?  288 VAL B C   1 
ATOM   7445  O O   . VAL B 1 299 ? 128.085 94.598  142.313 1.00 85.46  ?  288 VAL B O   1 
ATOM   7446  C CB  . VAL B 1 299 ? 124.976 94.994  142.458 1.00 85.46  ?  288 VAL B CB  1 
ATOM   7447  C CG1 . VAL B 1 299 ? 124.811 96.187  143.386 1.00 85.46  ?  288 VAL B CG1 1 
ATOM   7448  C CG2 . VAL B 1 299 ? 123.645 94.615  141.832 1.00 85.46  ?  288 VAL B CG2 1 
ATOM   7449  N N   . PRO B 1 300 ? 127.712 96.811  142.224 1.00 79.89  ?  289 PRO B N   1 
ATOM   7450  C CA  . PRO B 1 300 ? 128.964 97.051  142.940 1.00 79.89  ?  289 PRO B CA  1 
ATOM   7451  C C   . PRO B 1 300 ? 128.995 96.302  144.261 1.00 79.89  ?  289 PRO B C   1 
ATOM   7452  O O   . PRO B 1 300 ? 127.969 96.232  144.931 1.00 79.89  ?  289 PRO B O   1 
ATOM   7453  C CB  . PRO B 1 300 ? 128.941 98.561  143.196 1.00 79.89  ?  289 PRO B CB  1 
ATOM   7454  C CG  . PRO B 1 300 ? 127.594 99.050  142.762 1.00 79.89  ?  289 PRO B CG  1 
ATOM   7455  C CD  . PRO B 1 300 ? 127.083 98.059  141.769 1.00 79.89  ?  289 PRO B CD  1 
ATOM   7456  N N   . ILE B 1 301 ? 130.142 95.740  144.631 1.00 76.99  ?  290 ILE B N   1 
ATOM   7457  C CA  . ILE B 1 301 ? 130.265 95.073  145.920 1.00 76.99  ?  290 ILE B CA  1 
ATOM   7458  C C   . ILE B 1 301 ? 130.247 96.102  147.038 1.00 76.99  ?  290 ILE B C   1 
ATOM   7459  O O   . ILE B 1 301 ? 131.061 97.021  147.046 1.00 76.99  ?  290 ILE B O   1 
ATOM   7460  C CB  . ILE B 1 301 ? 131.564 94.257  146.022 1.00 76.99  ?  290 ILE B CB  1 
ATOM   7461  C CG1 . ILE B 1 301 ? 131.645 93.244  144.881 1.00 76.99  ?  290 ILE B CG1 1 
ATOM   7462  C CG2 . ILE B 1 301 ? 131.654 93.565  147.374 1.00 76.99  ?  290 ILE B CG2 1 
ATOM   7463  C CD1 . ILE B 1 301 ? 132.931 92.450  144.872 1.00 76.99  ?  290 ILE B CD1 1 
ATOM   7464  N N   . PRO B 1 302 ? 129.311 95.958  147.989 1.00 73.11  ?  291 PRO B N   1 
ATOM   7465  C CA  . PRO B 1 302 ? 129.197 96.915  149.097 1.00 73.11  ?  291 PRO B CA  1 
ATOM   7466  C C   . PRO B 1 302 ? 130.252 96.673  150.168 1.00 73.11  ?  291 PRO B C   1 
ATOM   7467  O O   . PRO B 1 302 ? 129.964 95.968  151.128 1.00 73.11  ?  291 PRO B O   1 
ATOM   7468  C CB  . PRO B 1 302 ? 127.805 96.614  149.648 1.00 73.11  ?  291 PRO B CB  1 
ATOM   7469  C CG  . PRO B 1 302 ? 127.583 95.173  149.346 1.00 73.11  ?  291 PRO B CG  1 
ATOM   7470  C CD  . PRO B 1 302 ? 128.294 94.896  148.054 1.00 73.11  ?  291 PRO B CD  1 
ATOM   7471  N N   . ILE B 1 303 ? 131.458 97.179  150.006 1.00 72.00  ?  292 ILE B N   1 
ATOM   7472  C CA  . ILE B 1 303 ? 132.498 96.870  150.974 1.00 72.00  ?  292 ILE B CA  1 
ATOM   7473  C C   . ILE B 1 303 ? 132.278 97.622  152.287 1.00 72.00  ?  292 ILE B C   1 
ATOM   7474  O O   . ILE B 1 303 ? 132.576 97.106  153.357 1.00 72.00  ?  292 ILE B O   1 
ATOM   7475  C CB  . ILE B 1 303 ? 133.898 97.159  150.398 1.00 72.00  ?  292 ILE B CB  1 
ATOM   7476  C CG1 . ILE B 1 303 ? 134.977 96.590  151.322 1.00 72.00  ?  292 ILE B CG1 1 
ATOM   7477  C CG2 . ILE B 1 303 ? 134.085 98.651  150.166 1.00 72.00  ?  292 ILE B CG2 1 
ATOM   7478  C CD1 . ILE B 1 303 ? 134.814 95.110  151.591 1.00 72.00  ?  292 ILE B CD1 1 
ATOM   7479  N N   . GLU B 1 304 ? 131.734 98.829  152.207 1.00 69.06  ?  293 GLU B N   1 
ATOM   7480  C CA  . GLU B 1 304 ? 131.519 99.631  153.407 1.00 69.06  ?  293 GLU B CA  1 
ATOM   7481  C C   . GLU B 1 304 ? 130.571 98.947  154.378 1.00 69.06  ?  293 GLU B C   1 
ATOM   7482  O O   . GLU B 1 304 ? 130.881 98.816  155.559 1.00 69.06  ?  293 GLU B O   1 
ATOM   7483  C CB  . GLU B 1 304 ? 130.980 101.010 153.037 1.00 69.06  ?  293 GLU B CB  1 
ATOM   7484  C CG  . GLU B 1 304 ? 131.955 101.855 152.235 1.00 69.06  ?  293 GLU B CG  1 
ATOM   7485  C CD  . GLU B 1 304 ? 131.447 103.263 152.004 1.00 69.06  ?  293 GLU B CD  1 
ATOM   7486  O OE1 . GLU B 1 304 ? 130.313 103.563 152.434 1.00 69.06  ?  293 GLU B OE1 1 
ATOM   7487  O OE2 . GLU B 1 304 ? 132.182 104.069 151.396 1.00 69.06  -1 293 GLU B OE2 1 
ATOM   7488  N N   . PHE B 1 305 ? 129.430 98.488  153.883 1.00 66.45  ?  294 PHE B N   1 
ATOM   7489  C CA  . PHE B 1 305 ? 128.485 97.786  154.731 1.00 66.45  ?  294 PHE B CA  1 
ATOM   7490  C C   . PHE B 1 305 ? 129.093 96.516  155.304 1.00 66.45  ?  294 PHE B C   1 
ATOM   7491  O O   . PHE B 1 305 ? 129.009 96.273  156.503 1.00 66.45  ?  294 PHE B O   1 
ATOM   7492  C CB  . PHE B 1 305 ? 127.230 97.442  153.937 1.00 66.45  ?  294 PHE B CB  1 
ATOM   7493  C CG  . PHE B 1 305 ? 126.241 96.616  154.697 1.00 66.45  ?  294 PHE B CG  1 
ATOM   7494  C CD1 . PHE B 1 305 ? 125.393 97.203  155.617 1.00 66.45  ?  294 PHE B CD1 1 
ATOM   7495  C CD2 . PHE B 1 305 ? 126.155 95.253  154.488 1.00 66.45  ?  294 PHE B CD2 1 
ATOM   7496  C CE1 . PHE B 1 305 ? 124.478 96.445  156.318 1.00 66.45  ?  294 PHE B CE1 1 
ATOM   7497  C CE2 . PHE B 1 305 ? 125.243 94.488  155.185 1.00 66.45  ?  294 PHE B CE2 1 
ATOM   7498  C CZ  . PHE B 1 305 ? 124.402 95.085  156.102 1.00 66.45  ?  294 PHE B CZ  1 
ATOM   7499  N N   . ILE B 1 306 ? 129.722 95.711  154.459 1.00 67.31  ?  295 ILE B N   1 
ATOM   7500  C CA  . ILE B 1 306 ? 130.278 94.449  154.918 1.00 67.31  ?  295 ILE B CA  1 
ATOM   7501  C C   . ILE B 1 306 ? 131.337 94.667  155.987 1.00 67.31  ?  295 ILE B C   1 
ATOM   7502  O O   . ILE B 1 306 ? 131.319 94.012  157.022 1.00 67.31  ?  295 ILE B O   1 
ATOM   7503  C CB  . ILE B 1 306 ? 130.884 93.656  153.749 1.00 67.31  ?  295 ILE B CB  1 
ATOM   7504  C CG1 . ILE B 1 306 ? 129.809 93.345  152.708 1.00 67.31  ?  295 ILE B CG1 1 
ATOM   7505  C CG2 . ILE B 1 306 ? 131.531 92.375  154.248 1.00 67.31  ?  295 ILE B CG2 1 
ATOM   7506  C CD1 . ILE B 1 306 ? 130.351 92.734  151.435 1.00 67.31  ?  295 ILE B CD1 1 
ATOM   7507  N N   . MET B 1 307 ? 132.250 95.597  155.746 1.00 67.22  ?  296 MET B N   1 
ATOM   7508  C CA  . MET B 1 307 ? 133.315 95.856  156.703 1.00 67.22  ?  296 MET B CA  1 
ATOM   7509  C C   . MET B 1 307 ? 132.775 96.368  158.027 1.00 67.22  ?  296 MET B C   1 
ATOM   7510  O O   . MET B 1 307 ? 133.198 95.916  159.081 1.00 67.22  ?  296 MET B O   1 
ATOM   7511  C CB  . MET B 1 307 ? 134.316 96.855  156.123 1.00 67.22  ?  296 MET B CB  1 
ATOM   7512  C CG  . MET B 1 307 ? 135.218 96.293  155.037 1.00 67.22  ?  296 MET B CG  1 
ATOM   7513  S SD  . MET B 1 307 ? 136.346 95.017  155.627 1.00 67.22  ?  296 MET B SD  1 
ATOM   7514  C CE  . MET B 1 307 ? 135.333 93.548  155.491 1.00 67.22  ?  296 MET B CE  1 
ATOM   7515  N N   . THR B 1 308 ? 131.841 97.305  157.974 1.00 63.84  ?  297 THR B N   1 
ATOM   7516  C CA  . THR B 1 308 ? 131.273 97.860  159.191 1.00 63.84  ?  297 THR B CA  1 
ATOM   7517  C C   . THR B 1 308 ? 130.540 96.795  159.987 1.00 63.84  ?  297 THR B C   1 
ATOM   7518  O O   . THR B 1 308 ? 130.588 96.791  161.209 1.00 63.84  ?  297 THR B O   1 
ATOM   7519  C CB  . THR B 1 308 ? 130.316 99.027  158.884 1.00 63.84  ?  297 THR B CB  1 
ATOM   7520  O OG1 . THR B 1 308 ? 129.337 98.604  157.928 1.00 63.84  ?  297 THR B OG1 1 
ATOM   7521  C CG2 . THR B 1 308 ? 131.087 100.209 158.324 1.00 63.84  ?  297 THR B CG2 1 
ATOM   7522  N N   . VAL B 1 309 ? 129.861 95.891  159.298 1.00 64.44  ?  298 VAL B N   1 
ATOM   7523  C CA  . VAL B 1 309 ? 129.161 94.809  159.980 1.00 64.44  ?  298 VAL B CA  1 
ATOM   7524  C C   . VAL B 1 309 ? 130.145 93.865  160.657 1.00 64.44  ?  298 VAL B C   1 
ATOM   7525  O O   . VAL B 1 309 ? 129.957 93.491  161.808 1.00 64.44  ?  298 VAL B O   1 
ATOM   7526  C CB  . VAL B 1 309 ? 128.261 94.016  159.012 1.00 64.44  ?  298 VAL B CB  1 
ATOM   7527  C CG1 . VAL B 1 309 ? 127.704 92.778  159.694 1.00 64.44  ?  298 VAL B CG1 1 
ATOM   7528  C CG2 . VAL B 1 309 ? 127.141 94.897  158.489 1.00 64.44  ?  298 VAL B CG2 1 
ATOM   7529  N N   . ILE B 1 310 ? 131.199 93.482  159.949 1.00 66.93  ?  299 ILE B N   1 
ATOM   7530  C CA  . ILE B 1 310 ? 132.209 92.613  160.536 1.00 66.93  ?  299 ILE B CA  1 
ATOM   7531  C C   . ILE B 1 310 ? 132.911 93.336  161.666 1.00 66.93  ?  299 ILE B C   1 
ATOM   7532  O O   . ILE B 1 310 ? 133.132 92.768  162.729 1.00 66.93  ?  299 ILE B O   1 
ATOM   7533  C CB  . ILE B 1 310 ? 133.246 92.158  159.494 1.00 66.93  ?  299 ILE B CB  1 
ATOM   7534  C CG1 . ILE B 1 310 ? 132.559 91.387  158.367 1.00 66.93  ?  299 ILE B CG1 1 
ATOM   7535  C CG2 . ILE B 1 310 ? 134.323 91.311  160.148 1.00 66.93  ?  299 ILE B CG2 1 
ATOM   7536  C CD1 . ILE B 1 310 ? 133.499 90.942  157.271 1.00 66.93  ?  299 ILE B CD1 1 
ATOM   7537  N N   . ALA B 1 311 ? 133.248 94.599  161.447 1.00 65.10  ?  300 ALA B N   1 
ATOM   7538  C CA  . ALA B 1 311 ? 133.910 95.376  162.474 1.00 65.10  ?  300 ALA B CA  1 
ATOM   7539  C C   . ALA B 1 311 ? 133.030 95.503  163.704 1.00 65.10  ?  300 ALA B C   1 
ATOM   7540  O O   . ALA B 1 311 ? 133.506 95.361  164.825 1.00 65.10  ?  300 ALA B O   1 
ATOM   7541  C CB  . ALA B 1 311 ? 134.274 96.749  161.941 1.00 65.10  ?  300 ALA B CB  1 
ATOM   7542  N N   . ALA B 1 312 ? 131.748 95.773  163.501 1.00 64.51  ?  301 ALA B N   1 
ATOM   7543  C CA  . ALA B 1 312 ? 130.832 95.910  164.620 1.00 64.51  ?  301 ALA B CA  1 
ATOM   7544  C C   . ALA B 1 312 ? 130.714 94.583  165.324 1.00 64.51  ?  301 ALA B C   1 
ATOM   7545  O O   . ALA B 1 312 ? 130.663 94.533  166.547 1.00 64.51  ?  301 ALA B O   1 
ATOM   7546  C CB  . ALA B 1 312 ? 129.477 96.389  164.147 1.00 64.51  ?  301 ALA B CB  1 
ATOM   7547  N N   . GLY B 1 313 ? 130.651 93.498  164.569 1.00 65.61  ?  302 GLY B N   1 
ATOM   7548  C CA  . GLY B 1 313 ? 130.543 92.176  165.156 1.00 65.61  ?  302 GLY B CA  1 
ATOM   7549  C C   . GLY B 1 313 ? 131.730 91.767  166.003 1.00 65.61  ?  302 GLY B C   1 
ATOM   7550  O O   . GLY B 1 313 ? 131.565 91.395  167.160 1.00 65.61  ?  302 GLY B O   1 
ATOM   7551  N N   . VAL B 1 314 ? 132.929 91.842  165.439 1.00 68.06  ?  303 VAL B N   1 
ATOM   7552  C CA  . VAL B 1 314 ? 134.133 91.448  166.167 1.00 68.06  ?  303 VAL B CA  1 
ATOM   7553  C C   . VAL B 1 314 ? 134.381 92.346  167.374 1.00 68.06  ?  303 VAL B C   1 
ATOM   7554  O O   . VAL B 1 314 ? 134.855 91.885  168.406 1.00 68.06  ?  303 VAL B O   1 
ATOM   7555  C CB  . VAL B 1 314 ? 135.370 91.437  165.246 1.00 68.06  ?  303 VAL B CB  1 
ATOM   7556  C CG1 . VAL B 1 314 ? 135.146 90.492  164.077 1.00 68.06  ?  303 VAL B CG1 1 
ATOM   7557  C CG2 . VAL B 1 314 ? 135.680 92.838  164.747 1.00 68.06  ?  303 VAL B CG2 1 
ATOM   7558  N N   . SER B 1 315 ? 134.066 93.625  167.254 1.00 67.92  ?  304 SER B N   1 
ATOM   7559  C CA  . SER B 1 315 ? 134.213 94.525  168.386 1.00 67.92  ?  304 SER B CA  1 
ATOM   7560  C C   . SER B 1 315 ? 133.252 94.136  169.503 1.00 67.92  ?  304 SER B C   1 
ATOM   7561  O O   . SER B 1 315 ? 133.614 94.179  170.673 1.00 67.92  ?  304 SER B O   1 
ATOM   7562  C CB  . SER B 1 315 ? 133.987 95.972  167.956 1.00 67.92  ?  304 SER B CB  1 
ATOM   7563  O OG  . SER B 1 315 ? 134.053 96.850  169.064 1.00 67.92  ?  304 SER B OG  1 
ATOM   7564  N N   . TYR B 1 316 ? 132.029 93.763  169.147 1.00 70.09  ?  305 TYR B N   1 
ATOM   7565  C CA  . TYR B 1 316 ? 131.042 93.365  170.148 1.00 70.09  ?  305 TYR B CA  1 
ATOM   7566  C C   . TYR B 1 316 ? 131.358 92.015  170.773 1.00 70.09  ?  305 TYR B C   1 
ATOM   7567  O O   . TYR B 1 316 ? 131.300 91.865  171.988 1.00 70.09  ?  305 TYR B O   1 
ATOM   7568  C CB  . TYR B 1 316 ? 129.643 93.332  169.536 1.00 70.09  ?  305 TYR B CB  1 
ATOM   7569  C CG  . TYR B 1 316 ? 128.572 92.905  170.506 1.00 70.09  ?  305 TYR B CG  1 
ATOM   7570  C CD1 . TYR B 1 316 ? 128.024 91.633  170.448 1.00 70.09  ?  305 TYR B CD1 1 
ATOM   7571  C CD2 . TYR B 1 316 ? 128.117 93.770  171.488 1.00 70.09  ?  305 TYR B CD2 1 
ATOM   7572  C CE1 . TYR B 1 316 ? 127.047 91.238  171.336 1.00 70.09  ?  305 TYR B CE1 1 
ATOM   7573  C CE2 . TYR B 1 316 ? 127.143 93.383  172.383 1.00 70.09  ?  305 TYR B CE2 1 
ATOM   7574  C CZ  . TYR B 1 316 ? 126.611 92.116  172.302 1.00 70.09  ?  305 TYR B CZ  1 
ATOM   7575  O OH  . TYR B 1 316 ? 125.637 91.726  173.189 1.00 70.09  ?  305 TYR B OH  1 
ATOM   7576  N N   . GLY B 1 317 ? 131.690 91.036  169.948 1.00 72.14  ?  306 GLY B N   1 
ATOM   7577  C CA  . GLY B 1 317 ? 132.010 89.718  170.455 1.00 72.14  ?  306 GLY B CA  1 
ATOM   7578  C C   . GLY B 1 317 ? 133.244 89.693  171.323 1.00 72.14  ?  306 GLY B C   1 
ATOM   7579  O O   . GLY B 1 317 ? 133.276 88.989  172.329 1.00 72.14  ?  306 GLY B O   1 
ATOM   7580  N N   . CYS B 1 318 ? 134.262 90.455  170.947 1.00 75.54  ?  307 CYS B N   1 
ATOM   7581  C CA  . CYS B 1 318 ? 135.513 90.452  171.691 1.00 75.54  ?  307 CYS B CA  1 
ATOM   7582  C C   . CYS B 1 318 ? 135.595 91.614  172.665 1.00 75.54  ?  307 CYS B C   1 
ATOM   7583  O O   . CYS B 1 318 ? 136.601 91.780  173.349 1.00 75.54  ?  307 CYS B O   1 
ATOM   7584  C CB  . CYS B 1 318 ? 136.690 90.490  170.722 1.00 75.54  ?  307 CYS B CB  1 
ATOM   7585  S SG  . CYS B 1 318 ? 136.574 89.301  169.367 1.00 75.54  ?  307 CYS B SG  1 
ATOM   7586  N N   . ASP B 1 319 ? 134.539 92.410  172.735 1.00 76.95  ?  308 ASP B N   1 
ATOM   7587  C CA  . ASP B 1 319 ? 134.506 93.544  173.653 1.00 76.95  ?  308 ASP B CA  1 
ATOM   7588  C C   . ASP B 1 319 ? 135.778 94.370  173.555 1.00 76.95  ?  308 ASP B C   1 
ATOM   7589  O O   . ASP B 1 319 ? 136.525 94.482  174.520 1.00 76.95  ?  308 ASP B O   1 
ATOM   7590  C CB  . ASP B 1 319 ? 134.287 93.060  175.089 1.00 76.95  ?  308 ASP B CB  1 
ATOM   7591  C CG  . ASP B 1 319 ? 134.105 94.201  176.072 1.00 76.95  ?  308 ASP B CG  1 
ATOM   7592  O OD1 . ASP B 1 319 ? 133.967 95.361  175.631 1.00 76.95  ?  308 ASP B OD1 1 
ATOM   7593  O OD2 . ASP B 1 319 ? 134.096 93.934  177.292 1.00 76.95  -1 308 ASP B OD2 1 
ATOM   7594  N N   . PHE B 1 320 ? 136.019 94.959  172.393 1.00 72.58  ?  309 PHE B N   1 
ATOM   7595  C CA  . PHE B 1 320 ? 137.215 95.759  172.201 1.00 72.58  ?  309 PHE B CA  1 
ATOM   7596  C C   . PHE B 1 320 ? 137.197 96.984  173.086 1.00 72.58  ?  309 PHE B C   1 
ATOM   7597  O O   . PHE B 1 320 ? 138.246 97.457  173.504 1.00 72.58  ?  309 PHE B O   1 
ATOM   7598  C CB  . PHE B 1 320 ? 137.337 96.178  170.740 1.00 72.58  ?  309 PHE B CB  1 
ATOM   7599  C CG  . PHE B 1 320 ? 137.772 95.075  169.825 1.00 72.58  ?  309 PHE B CG  1 
ATOM   7600  C CD1 . PHE B 1 320 ? 138.066 93.821  170.322 1.00 72.58  ?  309 PHE B CD1 1 
ATOM   7601  C CD2 . PHE B 1 320 ? 137.890 95.298  168.466 1.00 72.58  ?  309 PHE B CD2 1 
ATOM   7602  C CE1 . PHE B 1 320 ? 138.471 92.807  169.478 1.00 72.58  ?  309 PHE B CE1 1 
ATOM   7603  C CE2 . PHE B 1 320 ? 138.293 94.289  167.617 1.00 72.58  ?  309 PHE B CE2 1 
ATOM   7604  C CZ  . PHE B 1 320 ? 138.583 93.040  168.124 1.00 72.58  ?  309 PHE B CZ  1 
ATOM   7605  N N   . LYS B 1 321 ? 136.015 97.501  173.374 1.00 74.47  ?  310 LYS B N   1 
ATOM   7606  C CA  . LYS B 1 321 ? 135.898 98.699  174.181 1.00 74.47  ?  310 LYS B CA  1 
ATOM   7607  C C   . LYS B 1 321 ? 136.590 98.525  175.517 1.00 74.47  ?  310 LYS B C   1 
ATOM   7608  O O   . LYS B 1 321 ? 137.149 99.472  176.059 1.00 74.47  ?  310 LYS B O   1 
ATOM   7609  C CB  . LYS B 1 321 ? 134.426 99.023  174.410 1.00 74.47  ?  310 LYS B CB  1 
ATOM   7610  C CG  . LYS B 1 321 ? 134.182 100.361 175.079 1.00 74.47  ?  310 LYS B CG  1 
ATOM   7611  C CD  . LYS B 1 321 ? 132.788 100.420 175.674 1.00 74.47  ?  310 LYS B CD  1 
ATOM   7612  C CE  . LYS B 1 321 ? 131.742 99.980  174.665 1.00 74.47  ?  310 LYS B CE  1 
ATOM   7613  N NZ  . LYS B 1 321 ? 130.370 100.031 175.241 1.00 74.47  1  310 LYS B NZ  1 
ATOM   7614  N N   . ASN B 1 322 ? 136.485 97.321  176.060 1.00 78.10  ?  311 ASN B N   1 
ATOM   7615  C CA  . ASN B 1 322 ? 137.072 96.998  177.342 1.00 78.10  ?  311 ASN B CA  1 
ATOM   7616  C C   . ASN B 1 322 ? 138.388 96.273  177.188 1.00 78.10  ?  311 ASN B C   1 
ATOM   7617  O O   . ASN B 1 322 ? 139.353 96.571  177.877 1.00 78.10  ?  311 ASN B O   1 
ATOM   7618  C CB  . ASN B 1 322 ? 136.106 96.154  178.160 1.00 78.10  ?  311 ASN B CB  1 
ATOM   7619  C CG  . ASN B 1 322 ? 134.797 96.864  178.416 1.00 78.10  ?  311 ASN B CG  1 
ATOM   7620  O OD1 . ASN B 1 322 ? 133.728 96.264  178.353 1.00 78.10  ?  311 ASN B OD1 1 
ATOM   7621  N ND2 . ASN B 1 322 ? 134.874 98.151  178.698 1.00 78.10  ?  311 ASN B ND2 1 
ATOM   7622  N N   . ARG B 1 323 ? 138.431 95.309  176.287 1.00 79.08  ?  312 ARG B N   1 
ATOM   7623  C CA  . ARG B 1 323 ? 139.650 94.565  176.069 1.00 79.08  ?  312 ARG B CA  1 
ATOM   7624  C C   . ARG B 1 323 ? 140.787 95.428  175.541 1.00 79.08  ?  312 ARG B C   1 
ATOM   7625  O O   . ARG B 1 323 ? 141.916 95.304  175.992 1.00 79.08  ?  312 ARG B O   1 
ATOM   7626  C CB  . ARG B 1 323 ? 139.378 93.429  175.101 1.00 79.08  ?  312 ARG B CB  1 
ATOM   7627  C CG  . ARG B 1 323 ? 140.549 92.505  174.860 1.00 79.08  ?  312 ARG B CG  1 
ATOM   7628  C CD  . ARG B 1 323 ? 140.039 91.201  174.282 1.00 79.08  ?  312 ARG B CD  1 
ATOM   7629  N NE  . ARG B 1 323 ? 138.779 90.821  174.909 1.00 79.08  ?  312 ARG B NE  1 
ATOM   7630  C CZ  . ARG B 1 323 ? 138.249 89.605  174.854 1.00 79.08  ?  312 ARG B CZ  1 
ATOM   7631  N NH1 . ARG B 1 323 ? 137.095 89.357  175.454 1.00 79.08  1  312 ARG B NH1 1 
ATOM   7632  N NH2 . ARG B 1 323 ? 138.870 88.637  174.198 1.00 79.08  ?  312 ARG B NH2 1 
ATOM   7633  N N   . PHE B 1 324 ? 140.481 96.348  174.637 1.00 74.92  ?  313 PHE B N   1 
ATOM   7634  C CA  . PHE B 1 324 ? 141.499 97.215  174.081 1.00 74.92  ?  313 PHE B CA  1 
ATOM   7635  C C   . PHE B 1 324 ? 141.216 98.683  174.321 1.00 74.92  ?  313 PHE B C   1 
ATOM   7636  O O   . PHE B 1 324 ? 141.987 99.528  173.906 1.00 74.92  ?  313 PHE B O   1 
ATOM   7637  C CB  . PHE B 1 324 ? 141.632 96.976  172.587 1.00 74.92  ?  313 PHE B CB  1 
ATOM   7638  C CG  . PHE B 1 324 ? 141.965 95.567  172.232 1.00 74.92  ?  313 PHE B CG  1 
ATOM   7639  C CD1 . PHE B 1 324 ? 143.132 94.990  172.678 1.00 74.92  ?  313 PHE B CD1 1 
ATOM   7640  C CD2 . PHE B 1 324 ? 141.121 94.828  171.444 1.00 74.92  ?  313 PHE B CD2 1 
ATOM   7641  C CE1 . PHE B 1 324 ? 143.448 93.694  172.357 1.00 74.92  ?  313 PHE B CE1 1 
ATOM   7642  C CE2 . PHE B 1 324 ? 141.427 93.533  171.112 1.00 74.92  ?  313 PHE B CE2 1 
ATOM   7643  C CZ  . PHE B 1 324 ? 142.594 92.962  171.570 1.00 74.92  ?  313 PHE B CZ  1 
ATOM   7644  N N   . LYS B 1 325 ? 140.100 98.974  174.973 1.00 71.95  ?  314 LYS B N   1 
ATOM   7645  C CA  . LYS B 1 325 ? 139.657 100.338 175.271 1.00 71.95  ?  314 LYS B CA  1 
ATOM   7646  C C   . LYS B 1 325 ? 139.532 101.207 174.018 1.00 71.95  ?  314 LYS B C   1 
ATOM   7647  O O   . LYS B 1 325 ? 139.857 102.382 174.052 1.00 71.95  ?  314 LYS B O   1 
ATOM   7648  C CB  . LYS B 1 325 ? 140.531 101.022 176.338 1.00 71.95  ?  314 LYS B CB  1 
ATOM   7649  C CG  . LYS B 1 325 ? 140.776 100.199 177.587 1.00 71.95  ?  314 LYS B CG  1 
ATOM   7650  C CD  . LYS B 1 325 ? 139.570 100.216 178.512 1.00 71.95  ?  314 LYS B CD  1 
ATOM   7651  C CE  . LYS B 1 325 ? 139.611 99.068  179.510 1.00 71.95  ?  314 LYS B CE  1 
ATOM   7652  N NZ  . LYS B 1 325 ? 140.831 99.118  180.357 1.00 71.95  1  314 LYS B NZ  1 
ATOM   7653  N N   . VAL B 1 326 ? 139.030 100.629 172.930 1.00 66.73  ?  315 VAL B N   1 
ATOM   7654  C CA  . VAL B 1 326 ? 138.872 101.337 171.673 1.00 66.73  ?  315 VAL B CA  1 
ATOM   7655  C C   . VAL B 1 326 ? 137.713 102.304 171.775 1.00 66.73  ?  315 VAL B C   1 
ATOM   7656  O O   . VAL B 1 326 ? 136.797 102.091 172.555 1.00 66.73  ?  315 VAL B O   1 
ATOM   7657  C CB  . VAL B 1 326 ? 138.656 100.377 170.496 1.00 66.73  ?  315 VAL B CB  1 
ATOM   7658  C CG1 . VAL B 1 326 ? 139.793 99.390  170.396 1.00 66.73  ?  315 VAL B CG1 1 
ATOM   7659  C CG2 . VAL B 1 326 ? 137.337 99.652  170.626 1.00 66.73  ?  315 VAL B CG2 1 
ATOM   7660  N N   . ALA B 1 327 ? 137.746 103.362 170.978 1.00 62.68  ?  316 ALA B N   1 
ATOM   7661  C CA  . ALA B 1 327 ? 136.702 104.379 171.034 1.00 62.68  ?  316 ALA B CA  1 
ATOM   7662  C C   . ALA B 1 327 ? 135.540 103.988 170.150 1.00 62.68  ?  316 ALA B C   1 
ATOM   7663  O O   . ALA B 1 327 ? 135.706 103.788 168.951 1.00 62.68  ?  316 ALA B O   1 
ATOM   7664  C CB  . ALA B 1 327 ? 137.247 105.729 170.622 1.00 62.68  ?  316 ALA B CB  1 
ATOM   7665  N N   . VAL B 1 328 ? 134.358 103.879 170.737 1.00 60.84  ?  317 VAL B N   1 
ATOM   7666  C CA  . VAL B 1 328 ? 133.198 103.447 169.973 1.00 60.84  ?  317 VAL B CA  1 
ATOM   7667  C C   . VAL B 1 328 ? 132.166 104.542 169.787 1.00 60.84  ?  317 VAL B C   1 
ATOM   7668  O O   . VAL B 1 328 ? 132.154 105.519 170.527 1.00 60.84  ?  317 VAL B O   1 
ATOM   7669  C CB  . VAL B 1 328 ? 132.525 102.224 170.630 1.00 60.84  ?  317 VAL B CB  1 
ATOM   7670  C CG1 . VAL B 1 328 ? 133.446 101.015 170.573 1.00 60.84  ?  317 VAL B CG1 1 
ATOM   7671  C CG2 . VAL B 1 328 ? 132.121 102.539 172.059 1.00 60.84  ?  317 VAL B CG2 1 
ATOM   7672  N N   . VAL B 1 329 ? 131.265 104.280 168.839 1.00 59.71  ?  318 VAL B N   1 
ATOM   7673  C CA  . VAL B 1 329 ? 130.148 105.136 168.468 1.00 59.71  ?  318 VAL B CA  1 
ATOM   7674  C C   . VAL B 1 329 ? 129.196 105.334 169.637 1.00 59.71  ?  318 VAL B C   1 
ATOM   7675  O O   . VAL B 1 329 ? 128.707 106.432 169.861 1.00 59.71  ?  318 VAL B O   1 
ATOM   7676  C CB  . VAL B 1 329 ? 129.382 104.546 167.263 1.00 59.71  ?  318 VAL B CB  1 
ATOM   7677  C CG1 . VAL B 1 329 ? 128.079 105.288 167.019 1.00 59.71  ?  318 VAL B CG1 1 
ATOM   7678  C CG2 . VAL B 1 329 ? 130.249 104.571 166.016 1.00 59.71  ?  318 VAL B CG2 1 
ATOM   7679  N N   . GLY B 1 330 ? 128.903 104.256 170.352 1.00 63.45  ?  319 GLY B N   1 
ATOM   7680  C CA  . GLY B 1 330 ? 128.065 104.311 171.529 1.00 63.45  ?  319 GLY B CA  1 
ATOM   7681  C C   . GLY B 1 330 ? 126.580 104.369 171.301 1.00 63.45  ?  319 GLY B C   1 
ATOM   7682  O O   . GLY B 1 330 ? 126.106 104.280 170.184 1.00 63.45  ?  319 GLY B O   1 
ATOM   7683  N N   . ASP B 1 331 ? 125.842 104.510 172.387 1.00 67.28  ?  320 ASP B N   1 
ATOM   7684  C CA  . ASP B 1 331 ? 124.395 104.612 172.339 1.00 67.28  ?  320 ASP B CA  1 
ATOM   7685  C C   . ASP B 1 331 ? 123.918 105.946 171.791 1.00 67.28  ?  320 ASP B C   1 
ATOM   7686  O O   . ASP B 1 331 ? 124.456 106.989 172.126 1.00 67.28  ?  320 ASP B O   1 
ATOM   7687  C CB  . ASP B 1 331 ? 123.845 104.419 173.737 1.00 67.28  ?  320 ASP B CB  1 
ATOM   7688  C CG  . ASP B 1 331 ? 124.522 103.288 174.461 1.00 67.28  ?  320 ASP B CG  1 
ATOM   7689  O OD1 . ASP B 1 331 ? 124.729 102.231 173.833 1.00 67.28  ?  320 ASP B OD1 1 
ATOM   7690  O OD2 . ASP B 1 331 ? 124.855 103.453 175.651 1.00 67.28  -1 320 ASP B OD2 1 
ATOM   7691  N N   . MET B 1 332 ? 122.887 105.902 170.959 1.00 64.08  ?  321 MET B N   1 
ATOM   7692  C CA  . MET B 1 332 ? 122.301 107.093 170.372 1.00 64.08  ?  321 MET B CA  1 
ATOM   7693  C C   . MET B 1 332 ? 120.845 107.112 170.776 1.00 64.08  ?  321 MET B C   1 
ATOM   7694  O O   . MET B 1 332 ? 120.214 106.069 170.791 1.00 64.08  ?  321 MET B O   1 
ATOM   7695  C CB  . MET B 1 332 ? 122.396 107.035 168.855 1.00 64.08  ?  321 MET B CB  1 
ATOM   7696  C CG  . MET B 1 332 ? 123.755 106.632 168.330 1.00 64.08  ?  321 MET B CG  1 
ATOM   7697  S SD  . MET B 1 332 ? 123.897 106.843 166.553 1.00 64.08  ?  321 MET B SD  1 
ATOM   7698  C CE  . MET B 1 332 ? 123.539 105.205 165.942 1.00 64.08  ?  321 MET B CE  1 
ATOM   7699  N N   . ASN B 1 333 ? 120.319 108.272 171.158 1.00 65.33  ?  322 ASN B N   1 
ATOM   7700  C CA  . ASN B 1 333 ? 118.911 108.350 171.526 1.00 65.33  ?  322 ASN B CA  1 
ATOM   7701  C C   . ASN B 1 333 ? 118.138 107.933 170.295 1.00 65.33  ?  322 ASN B C   1 
ATOM   7702  O O   . ASN B 1 333 ? 118.341 108.487 169.226 1.00 65.33  ?  322 ASN B O   1 
ATOM   7703  C CB  . ASN B 1 333 ? 118.516 109.757 171.981 1.00 65.33  ?  322 ASN B CB  1 
ATOM   7704  C CG  . ASN B 1 333 ? 118.669 110.799 170.883 1.00 65.33  ?  322 ASN B CG  1 
ATOM   7705  O OD1 . ASN B 1 333 ? 119.289 110.544 169.848 1.00 65.33  ?  322 ASN B OD1 1 
ATOM   7706  N ND2 . ASN B 1 333 ? 118.107 111.981 171.108 1.00 65.33  ?  322 ASN B ND2 1 
ATOM   7707  N N   . PRO B 1 334 ? 117.259 106.936 170.439 1.00 62.16  ?  323 PRO B N   1 
ATOM   7708  C CA  . PRO B 1 334 ? 116.503 106.389 169.314 1.00 62.16  ?  323 PRO B CA  1 
ATOM   7709  C C   . PRO B 1 334 ? 115.335 107.222 168.834 1.00 62.16  ?  323 PRO B C   1 
ATOM   7710  O O   . PRO B 1 334 ? 114.203 106.797 168.972 1.00 62.16  ?  323 PRO B O   1 
ATOM   7711  C CB  . PRO B 1 334 ? 115.988 105.069 169.865 1.00 62.16  ?  323 PRO B CB  1 
ATOM   7712  C CG  . PRO B 1 334 ? 115.835 105.318 171.320 1.00 62.16  ?  323 PRO B CG  1 
ATOM   7713  C CD  . PRO B 1 334 ? 116.903 106.290 171.709 1.00 62.16  ?  323 PRO B CD  1 
ATOM   7714  N N   . GLY B 1 335 ? 115.597 108.377 168.254 1.00 55.42  ?  324 GLY B N   1 
ATOM   7715  C CA  . GLY B 1 335 ? 114.528 109.195 167.745 1.00 55.42  ?  324 GLY B CA  1 
ATOM   7716  C C   . GLY B 1 335 ? 115.063 110.500 167.237 1.00 55.42  ?  324 GLY B C   1 
ATOM   7717  O O   . GLY B 1 335 ? 116.252 110.686 167.139 1.00 55.42  ?  324 GLY B O   1 
ATOM   7718  N N   . PHE B 1 336 ? 114.166 111.403 166.894 1.00 52.83  ?  325 PHE B N   1 
ATOM   7719  C CA  . PHE B 1 336 ? 114.546 112.726 166.430 1.00 52.83  ?  325 PHE B CA  1 
ATOM   7720  C C   . PHE B 1 336 ? 114.507 113.737 167.561 1.00 52.83  ?  325 PHE B C   1 
ATOM   7721  O O   . PHE B 1 336 ? 113.878 113.504 168.584 1.00 52.83  ?  325 PHE B O   1 
ATOM   7722  C CB  . PHE B 1 336 ? 113.627 113.182 165.291 1.00 52.83  ?  325 PHE B CB  1 
ATOM   7723  C CG  . PHE B 1 336 ? 113.814 112.420 164.012 1.00 52.83  ?  325 PHE B CG  1 
ATOM   7724  C CD1 . PHE B 1 336 ? 114.749 112.830 163.078 1.00 52.83  ?  325 PHE B CD1 1 
ATOM   7725  C CD2 . PHE B 1 336 ? 113.047 111.302 163.739 1.00 52.83  ?  325 PHE B CD2 1 
ATOM   7726  C CE1 . PHE B 1 336 ? 114.922 112.136 161.899 1.00 52.83  ?  325 PHE B CE1 1 
ATOM   7727  C CE2 . PHE B 1 336 ? 113.213 110.605 162.560 1.00 52.83  ?  325 PHE B CE2 1 
ATOM   7728  C CZ  . PHE B 1 336 ? 114.153 111.021 161.638 1.00 52.83  ?  325 PHE B CZ  1 
ATOM   7729  N N   . GLN B 1 337 ? 115.186 114.858 167.380 1.00 56.28  ?  326 GLN B N   1 
ATOM   7730  C CA  . GLN B 1 337 ? 115.200 115.896 168.394 1.00 56.28  ?  326 GLN B CA  1 
ATOM   7731  C C   . GLN B 1 337 ? 114.134 116.929 168.108 1.00 56.28  ?  326 GLN B C   1 
ATOM   7732  O O   . GLN B 1 337 ? 113.755 117.131 166.958 1.00 56.28  ?  326 GLN B O   1 
ATOM   7733  C CB  . GLN B 1 337 ? 116.560 116.586 168.432 1.00 56.28  ?  326 GLN B CB  1 
ATOM   7734  C CG  . GLN B 1 337 ? 117.756 115.653 168.466 1.00 56.28  ?  326 GLN B CG  1 
ATOM   7735  C CD  . GLN B 1 337 ? 118.061 115.132 169.854 1.00 56.28  ?  326 GLN B CD  1 
ATOM   7736  O OE1 . GLN B 1 337 ? 119.002 114.364 170.044 1.00 56.28  ?  326 GLN B OE1 1 
ATOM   7737  N NE2 . GLN B 1 337 ? 117.269 115.552 170.832 1.00 56.28  ?  326 GLN B NE2 1 
ATOM   7738  N N   . PRO B 1 338 ? 113.644 117.599 169.155 1.00 57.13  ?  327 PRO B N   1 
ATOM   7739  C CA  . PRO B 1 338 ? 112.665 118.669 168.960 1.00 57.13  ?  327 PRO B CA  1 
ATOM   7740  C C   . PRO B 1 338 ? 113.261 119.837 168.189 1.00 57.13  ?  327 PRO B C   1 
ATOM   7741  O O   . PRO B 1 338 ? 114.465 120.059 168.262 1.00 57.13  ?  327 PRO B O   1 
ATOM   7742  C CB  . PRO B 1 338 ? 112.352 119.110 170.388 1.00 57.13  ?  327 PRO B CB  1 
ATOM   7743  C CG  . PRO B 1 338 ? 112.751 117.966 171.255 1.00 57.13  ?  327 PRO B CG  1 
ATOM   7744  C CD  . PRO B 1 338 ? 113.933 117.354 170.575 1.00 57.13  ?  327 PRO B CD  1 
ATOM   7745  N N   . PRO B 1 339 ? 112.427 120.592 167.469 1.00 56.22  ?  328 PRO B N   1 
ATOM   7746  C CA  . PRO B 1 339 ? 112.903 121.748 166.701 1.00 56.22  ?  328 PRO B CA  1 
ATOM   7747  C C   . PRO B 1 339 ? 113.656 122.761 167.553 1.00 56.22  ?  328 PRO B C   1 
ATOM   7748  O O   . PRO B 1 339 ? 113.449 122.826 168.760 1.00 56.22  ?  328 PRO B O   1 
ATOM   7749  C CB  . PRO B 1 339 ? 111.611 122.363 166.183 1.00 56.22  ?  328 PRO B CB  1 
ATOM   7750  C CG  . PRO B 1 339 ? 110.675 121.212 166.067 1.00 56.22  ?  328 PRO B CG  1 
ATOM   7751  C CD  . PRO B 1 339 ? 111.002 120.312 167.223 1.00 56.22  ?  328 PRO B CD  1 
ATOM   7752  N N   . ILE B 1 340 ? 114.524 123.544 166.930 1.00 57.23  ?  329 ILE B N   1 
ATOM   7753  C CA  . ILE B 1 340 ? 115.326 124.509 167.665 1.00 57.23  ?  329 ILE B CA  1 
ATOM   7754  C C   . ILE B 1 340 ? 115.291 125.885 167.005 1.00 57.23  ?  329 ILE B C   1 
ATOM   7755  O O   . ILE B 1 340 ? 114.959 125.987 165.828 1.00 57.23  ?  329 ILE B O   1 
ATOM   7756  C CB  . ILE B 1 340 ? 116.781 124.001 167.808 1.00 57.23  ?  329 ILE B CB  1 
ATOM   7757  C CG1 . ILE B 1 340 ? 117.545 124.808 168.858 1.00 57.23  ?  329 ILE B CG1 1 
ATOM   7758  C CG2 . ILE B 1 340 ? 117.501 124.044 166.468 1.00 57.23  ?  329 ILE B CG2 1 
ATOM   7759  C CD1 . ILE B 1 340 ? 118.979 124.361 169.031 1.00 57.23  ?  329 ILE B CD1 1 
ATOM   7760  N N   . THR B 1 341 ? 115.424 126.961 167.765 1.00 60.99  ?  330 THR B N   1 
ATOM   7761  C CA  . THR B 1 341 ? 115.441 128.280 167.184 1.00 60.99  ?  330 THR B CA  1 
ATOM   7762  C C   . THR B 1 341 ? 116.904 128.574 166.983 1.00 60.99  ?  330 THR B C   1 
ATOM   7763  O O   . THR B 1 341 ? 117.706 128.285 167.850 1.00 60.99  ?  330 THR B O   1 
ATOM   7764  C CB  . THR B 1 341 ? 114.835 129.304 168.149 1.00 60.99  ?  330 THR B CB  1 
ATOM   7765  O OG1 . THR B 1 341 ? 113.527 128.870 168.527 1.00 60.99  ?  330 THR B OG1 1 
ATOM   7766  C CG2 . THR B 1 341 ? 114.738 130.668 167.507 1.00 60.99  ?  330 THR B CG2 1 
ATOM   7767  N N   . PRO B 1 342 ? 117.266 129.117 165.822 1.00 60.99  ?  331 PRO B N   1 
ATOM   7768  C CA  . PRO B 1 342 ? 118.670 129.439 165.586 1.00 60.99  ?  331 PRO B CA  1 
ATOM   7769  C C   . PRO B 1 342 ? 119.145 130.559 166.497 1.00 60.99  ?  331 PRO B C   1 
ATOM   7770  O O   . PRO B 1 342 ? 118.366 131.432 166.859 1.00 60.99  ?  331 PRO B O   1 
ATOM   7771  C CB  . PRO B 1 342 ? 118.688 129.902 164.130 1.00 60.99  ?  331 PRO B CB  1 
ATOM   7772  C CG  . PRO B 1 342 ? 117.419 129.433 163.535 1.00 60.99  ?  331 PRO B CG  1 
ATOM   7773  C CD  . PRO B 1 342 ? 116.427 129.324 164.634 1.00 60.99  ?  331 PRO B CD  1 
ATOM   7774  N N   . ASP B 1 343 ? 120.423 130.549 166.841 1.00 63.17  ?  332 ASP B N   1 
ATOM   7775  C CA  . ASP B 1 343 ? 120.989 131.561 167.712 1.00 63.17  ?  332 ASP B CA  1 
ATOM   7776  C C   . ASP B 1 343 ? 121.537 132.695 166.862 1.00 63.17  ?  332 ASP B C   1 
ATOM   7777  O O   . ASP B 1 343 ? 122.393 132.469 166.022 1.00 63.17  ?  332 ASP B O   1 
ATOM   7778  C CB  . ASP B 1 343 ? 122.117 130.945 168.528 1.00 63.17  ?  332 ASP B CB  1 
ATOM   7779  C CG  . ASP B 1 343 ? 122.358 131.665 169.835 1.00 63.17  ?  332 ASP B CG  1 
ATOM   7780  O OD1 . ASP B 1 343 ? 123.423 131.455 170.452 1.00 63.17  ?  332 ASP B OD1 1 
ATOM   7781  O OD2 . ASP B 1 343 ? 121.482 132.441 170.258 1.00 63.17  -1 332 ASP B OD2 1 
ATOM   7782  N N   . VAL B 1 344 ? 121.056 133.914 167.101 1.00 63.08  ?  333 VAL B N   1 
ATOM   7783  C CA  . VAL B 1 344 ? 121.494 135.090 166.353 1.00 63.08  ?  333 VAL B CA  1 
ATOM   7784  C C   . VAL B 1 344 ? 122.919 135.483 166.702 1.00 63.08  ?  333 VAL B C   1 
ATOM   7785  O O   . VAL B 1 344 ? 123.616 136.038 165.869 1.00 63.08  ?  333 VAL B O   1 
ATOM   7786  C CB  . VAL B 1 344 ? 120.535 136.284 166.499 1.00 63.08  ?  333 VAL B CB  1 
ATOM   7787  C CG1 . VAL B 1 344 ? 119.217 135.994 165.806 1.00 63.08  ?  333 VAL B CG1 1 
ATOM   7788  C CG2 . VAL B 1 344 ? 120.315 136.627 167.959 1.00 63.08  ?  333 VAL B CG2 1 
ATOM   7789  N N   . GLU B 1 345 ? 123.329 135.276 167.948 1.00 65.22  ?  334 GLU B N   1 
ATOM   7790  C CA  . GLU B 1 345 ? 124.727 135.487 168.293 1.00 65.22  ?  334 GLU B CA  1 
ATOM   7791  C C   . GLU B 1 345 ? 125.614 134.616 167.424 1.00 65.22  ?  334 GLU B C   1 
ATOM   7792  O O   . GLU B 1 345 ? 126.617 135.086 166.897 1.00 65.22  ?  334 GLU B O   1 
ATOM   7793  C CB  . GLU B 1 345 ? 124.986 135.203 169.770 1.00 65.22  ?  334 GLU B CB  1 
ATOM   7794  C CG  . GLU B 1 345 ? 126.406 135.511 170.210 1.00 65.22  ?  334 GLU B CG  1 
ATOM   7795  C CD  . GLU B 1 345 ? 126.670 135.129 171.652 1.00 65.22  ?  334 GLU B CD  1 
ATOM   7796  O OE1 . GLU B 1 345 ? 125.808 134.461 172.259 1.00 65.22  ?  334 GLU B OE1 1 
ATOM   7797  O OE2 . GLU B 1 345 ? 127.742 135.492 172.176 1.00 65.22  -1 334 GLU B OE2 1 
ATOM   7798  N N   . THR B 1 346 ? 125.242 133.353 167.255 1.00 61.07  ?  335 THR B N   1 
ATOM   7799  C CA  . THR B 1 346 ? 126.000 132.476 166.374 1.00 61.07  ?  335 THR B CA  1 
ATOM   7800  C C   . THR B 1 346 ? 125.935 133.017 164.953 1.00 61.07  ?  335 THR B C   1 
ATOM   7801  O O   . THR B 1 346 ? 126.939 133.045 164.256 1.00 61.07  ?  335 THR B O   1 
ATOM   7802  C CB  . THR B 1 346 ? 125.483 131.027 166.430 1.00 61.07  ?  335 THR B CB  1 
ATOM   7803  O OG1 . THR B 1 346 ? 125.546 130.545 167.777 1.00 61.07  ?  335 THR B OG1 1 
ATOM   7804  C CG2 . THR B 1 346 ? 126.319 130.123 165.535 1.00 61.07  ?  335 THR B CG2 1 
ATOM   7805  N N   . PHE B 1 347 ? 124.768 133.470 164.510 1.00 58.06  ?  336 PHE B N   1 
ATOM   7806  C CA  . PHE B 1 347 ? 124.629 134.055 163.177 1.00 58.06  ?  336 PHE B CA  1 
ATOM   7807  C C   . PHE B 1 347 ? 125.617 135.192 162.959 1.00 58.06  ?  336 PHE B C   1 
ATOM   7808  O O   . PHE B 1 347 ? 126.324 135.208 161.972 1.00 58.06  ?  336 PHE B O   1 
ATOM   7809  C CB  . PHE B 1 347 ? 123.222 134.600 162.952 1.00 58.06  ?  336 PHE B CB  1 
ATOM   7810  C CG  . PHE B 1 347 ? 122.250 133.610 162.390 1.00 58.06  ?  336 PHE B CG  1 
ATOM   7811  C CD1 . PHE B 1 347 ? 122.350 132.271 162.683 1.00 58.06  ?  336 PHE B CD1 1 
ATOM   7812  C CD2 . PHE B 1 347 ? 121.204 134.034 161.609 1.00 58.06  ?  336 PHE B CD2 1 
ATOM   7813  C CE1 . PHE B 1 347 ? 121.442 131.372 162.186 1.00 58.06  ?  336 PHE B CE1 1 
ATOM   7814  C CE2 . PHE B 1 347 ? 120.291 133.139 161.107 1.00 58.06  ?  336 PHE B CE2 1 
ATOM   7815  C CZ  . PHE B 1 347 ? 120.413 131.802 161.393 1.00 58.06  ?  336 PHE B CZ  1 
ATOM   7816  N N   . GLN B 1 348 ? 125.671 136.140 163.889 1.00 61.83  ?  337 GLN B N   1 
ATOM   7817  C CA  . GLN B 1 348 ? 126.570 137.284 163.768 1.00 61.83  ?  337 GLN B CA  1 
ATOM   7818  C C   . GLN B 1 348 ? 128.024 136.892 163.757 1.00 61.83  ?  337 GLN B C   1 
ATOM   7819  O O   . GLN B 1 348 ? 128.827 137.460 163.040 1.00 61.83  ?  337 GLN B O   1 
ATOM   7820  C CB  . GLN B 1 348 ? 126.389 138.268 164.915 1.00 61.83  ?  337 GLN B CB  1 
ATOM   7821  C CG  . GLN B 1 348 ? 126.731 137.756 166.293 1.00 61.83  ?  337 GLN B CG  1 
ATOM   7822  C CD  . GLN B 1 348 ? 126.511 138.822 167.350 1.00 61.83  ?  337 GLN B CD  1 
ATOM   7823  O OE1 . GLN B 1 348 ? 125.783 139.786 167.133 1.00 61.83  ?  337 GLN B OE1 1 
ATOM   7824  N NE2 . GLN B 1 348 ? 127.150 138.652 168.504 1.00 61.83  ?  337 GLN B NE2 1 
ATOM   7825  N N   . ASN B 1 349 ? 128.360 135.927 164.587 1.00 62.02  ?  338 ASN B N   1 
ATOM   7826  C CA  . ASN B 1 349 ? 129.719 135.472 164.713 1.00 62.02  ?  338 ASN B CA  1 
ATOM   7827  C C   . ASN B 1 349 ? 130.205 134.566 163.616 1.00 62.02  ?  338 ASN B C   1 
ATOM   7828  O O   . ASN B 1 349 ? 131.393 134.302 163.529 1.00 62.02  ?  338 ASN B O   1 
ATOM   7829  C CB  . ASN B 1 349 ? 129.877 134.732 166.033 1.00 62.02  ?  338 ASN B CB  1 
ATOM   7830  C CG  . ASN B 1 349 ? 129.797 135.645 167.227 1.00 62.02  ?  338 ASN B CG  1 
ATOM   7831  O OD1 . ASN B 1 349 ? 130.219 136.792 167.170 1.00 62.02  ?  338 ASN B OD1 1 
ATOM   7832  N ND2 . ASN B 1 349 ? 129.279 135.129 168.324 1.00 62.02  ?  338 ASN B ND2 1 
ATOM   7833  N N   . THR B 1 350 ? 129.299 134.070 162.778 1.00 56.94  ?  339 THR B N   1 
ATOM   7834  C CA  . THR B 1 350 ? 129.692 133.101 161.752 1.00 56.94  ?  339 THR B CA  1 
ATOM   7835  C C   . THR B 1 350 ? 129.218 133.443 160.351 1.00 56.94  ?  339 THR B C   1 
ATOM   7836  O O   . THR B 1 350 ? 129.251 132.596 159.471 1.00 56.94  ?  339 THR B O   1 
ATOM   7837  C CB  . THR B 1 350 ? 129.147 131.699 162.089 1.00 56.94  ?  339 THR B CB  1 
ATOM   7838  O OG1 . THR B 1 350 ? 127.715 131.735 162.118 1.00 56.94  ?  339 THR B OG1 1 
ATOM   7839  C CG2 . THR B 1 350 ? 129.666 131.230 163.434 1.00 56.94  ?  339 THR B CG2 1 
ATOM   7840  N N   . VAL B 1 351 ? 128.796 134.677 160.128 1.00 53.85  ?  340 VAL B N   1 
ATOM   7841  C CA  . VAL B 1 351 ? 128.230 135.034 158.828 1.00 53.85  ?  340 VAL B CA  1 
ATOM   7842  C C   . VAL B 1 351 ? 129.171 134.744 157.650 1.00 53.85  ?  340 VAL B C   1 
ATOM   7843  O O   . VAL B 1 351 ? 128.747 134.168 156.651 1.00 53.85  ?  340 VAL B O   1 
ATOM   7844  C CB  . VAL B 1 351 ? 127.771 136.513 158.806 1.00 53.85  ?  340 VAL B CB  1 
ATOM   7845  C CG1 . VAL B 1 351 ? 128.873 137.425 159.319 1.00 53.85  ?  340 VAL B CG1 1 
ATOM   7846  C CG2 . VAL B 1 351 ? 127.323 136.915 157.411 1.00 53.85  ?  340 VAL B CG2 1 
ATOM   7847  N N   . GLY B 1 352 ? 130.436 135.119 157.766 1.00 51.81  ?  341 GLY B N   1 
ATOM   7848  C CA  . GLY B 1 352 ? 131.392 134.851 156.707 1.00 51.81  ?  341 GLY B CA  1 
ATOM   7849  C C   . GLY B 1 352 ? 131.614 133.376 156.458 1.00 51.81  ?  341 GLY B C   1 
ATOM   7850  O O   . GLY B 1 352 ? 131.712 132.945 155.312 1.00 51.81  ?  341 GLY B O   1 
ATOM   7851  N N   . ASP B 1 353 ? 131.718 132.595 157.523 1.00 52.06  ?  342 ASP B N   1 
ATOM   7852  C CA  . ASP B 1 353 ? 131.870 131.157 157.378 1.00 52.06  ?  342 ASP B CA  1 
ATOM   7853  C C   . ASP B 1 353 ? 130.663 130.553 156.674 1.00 52.06  ?  342 ASP B C   1 
ATOM   7854  O O   . ASP B 1 353 ? 130.813 129.694 155.815 1.00 52.06  ?  342 ASP B O   1 
ATOM   7855  C CB  . ASP B 1 353 ? 132.063 130.507 158.746 1.00 52.06  ?  342 ASP B CB  1 
ATOM   7856  C CG  . ASP B 1 353 ? 133.403 130.832 159.362 1.00 52.06  ?  342 ASP B CG  1 
ATOM   7857  O OD1 . ASP B 1 353 ? 134.296 131.306 158.630 1.00 52.06  ?  342 ASP B OD1 1 
ATOM   7858  O OD2 . ASP B 1 353 ? 133.566 130.606 160.578 1.00 52.06  -1 342 ASP B OD2 1 
ATOM   7859  N N   . CYS B 1 354 ? 129.469 131.011 157.027 1.00 49.73  ?  343 CYS B N   1 
ATOM   7860  C CA  . CYS B 1 354 ? 128.255 130.505 156.398 1.00 49.73  ?  343 CYS B CA  1 
ATOM   7861  C C   . CYS B 1 354 ? 128.202 130.842 154.915 1.00 49.73  ?  343 CYS B C   1 
ATOM   7862  O O   . CYS B 1 354 ? 127.705 130.049 154.127 1.00 49.73  ?  343 CYS B O   1 
ATOM   7863  C CB  . CYS B 1 354 ? 127.020 131.027 157.134 1.00 49.73  ?  343 CYS B CB  1 
ATOM   7864  S SG  . CYS B 1 354 ? 126.923 130.514 158.862 1.00 49.73  ?  343 CYS B SG  1 
ATOM   7865  N N   . PHE B 1 355 ? 128.761 131.976 154.518 1.00 47.87  ?  344 PHE B N   1 
ATOM   7866  C CA  . PHE B 1 355 ? 128.809 132.373 153.111 1.00 47.87  ?  344 PHE B CA  1 
ATOM   7867  C C   . PHE B 1 355 ? 129.698 131.431 152.333 1.00 47.87  ?  344 PHE B C   1 
ATOM   7868  O O   . PHE B 1 355 ? 129.418 131.109 151.203 1.00 47.87  ?  344 PHE B O   1 
ATOM   7869  C CB  . PHE B 1 355 ? 129.326 133.804 152.938 1.00 47.87  ?  344 PHE B CB  1 
ATOM   7870  C CG  . PHE B 1 355 ? 128.244 134.819 152.811 1.00 47.87  ?  344 PHE B CG  1 
ATOM   7871  C CD1 . PHE B 1 355 ? 127.627 135.040 151.598 1.00 47.87  ?  344 PHE B CD1 1 
ATOM   7872  C CD2 . PHE B 1 355 ? 127.830 135.545 153.909 1.00 47.87  ?  344 PHE B CD2 1 
ATOM   7873  C CE1 . PHE B 1 355 ? 126.616 135.968 151.484 1.00 47.87  ?  344 PHE B CE1 1 
ATOM   7874  C CE2 . PHE B 1 355 ? 126.818 136.472 153.798 1.00 47.87  ?  344 PHE B CE2 1 
ATOM   7875  C CZ  . PHE B 1 355 ? 126.210 136.682 152.586 1.00 47.87  ?  344 PHE B CZ  1 
ATOM   7876  N N   . GLY B 1 356 ? 130.825 131.073 152.931 1.00 45.20  ?  345 GLY B N   1 
ATOM   7877  C CA  . GLY B 1 356 ? 131.763 130.136 152.356 1.00 45.20  ?  345 GLY B CA  1 
ATOM   7878  C C   . GLY B 1 356 ? 131.213 128.739 152.245 1.00 45.20  ?  345 GLY B C   1 
ATOM   7879  O O   . GLY B 1 356 ? 131.472 128.043 151.297 1.00 45.20  ?  345 GLY B O   1 
ATOM   7880  N N   . ILE B 1 357 ? 130.491 128.316 153.270 1.00 43.65  ?  346 ILE B N   1 
ATOM   7881  C CA  . ILE B 1 357 ? 129.864 127.013 153.303 1.00 43.65  ?  346 ILE B CA  1 
ATOM   7882  C C   . ILE B 1 357 ? 128.801 126.902 152.220 1.00 43.65  ?  346 ILE B C   1 
ATOM   7883  O O   . ILE B 1 357 ? 128.689 125.887 151.565 1.00 43.65  ?  346 ILE B O   1 
ATOM   7884  C CB  . ILE B 1 357 ? 129.292 126.708 154.700 1.00 43.65  ?  346 ILE B CB  1 
ATOM   7885  C CG1 . ILE B 1 357 ? 130.418 126.285 155.646 1.00 43.65  ?  346 ILE B CG1 1 
ATOM   7886  C CG2 . ILE B 1 357 ? 128.235 125.623 154.632 1.00 43.65  ?  346 ILE B CG2 1 
ATOM   7887  C CD1 . ILE B 1 357 ? 130.193 126.644 157.089 1.00 43.65  ?  346 ILE B CD1 1 
ATOM   7888  N N   . ALA B 1 358 ? 128.023 127.959 152.041 1.00 43.20  ?  347 ALA B N   1 
ATOM   7889  C CA  . ALA B 1 358 ? 126.989 128.000 151.032 1.00 43.20  ?  347 ALA B CA  1 
ATOM   7890  C C   . ALA B 1 358 ? 127.539 127.911 149.613 1.00 43.20  ?  347 ALA B C   1 
ATOM   7891  O O   . ALA B 1 358 ? 126.959 127.232 148.792 1.00 43.20  ?  347 ALA B O   1 
ATOM   7892  C CB  . ALA B 1 358 ? 126.147 129.248 151.199 1.00 43.20  ?  347 ALA B CB  1 
ATOM   7893  N N   . MET B 1 359 ? 128.621 128.626 149.316 1.00 45.10  ?  348 MET B N   1 
ATOM   7894  C CA  . MET B 1 359 ? 129.215 128.564 147.992 1.00 45.10  ?  348 MET B CA  1 
ATOM   7895  C C   . MET B 1 359 ? 129.782 127.193 147.678 1.00 45.10  ?  348 MET B C   1 
ATOM   7896  O O   . MET B 1 359 ? 129.588 126.698 146.596 1.00 45.10  ?  348 MET B O   1 
ATOM   7897  C CB  . MET B 1 359 ? 130.265 129.668 147.776 1.00 45.10  ?  348 MET B CB  1 
ATOM   7898  C CG  . MET B 1 359 ? 131.085 129.605 146.466 1.00 45.10  ?  348 MET B CG  1 
ATOM   7899  S SD  . MET B 1 359 ? 130.315 129.646 144.808 1.00 45.10  ?  348 MET B SD  1 
ATOM   7900  C CE  . MET B 1 359 ? 131.431 130.725 143.930 1.00 45.10  ?  348 MET B CE  1 
ATOM   7901  N N   . VAL B 1 360 ? 130.481 126.595 148.634 1.00 43.69  ?  349 VAL B N   1 
ATOM   7902  C CA  . VAL B 1 360 ? 131.082 125.278 148.476 1.00 43.69  ?  349 VAL B CA  1 
ATOM   7903  C C   . VAL B 1 360 ? 130.070 124.164 148.297 1.00 43.69  ?  349 VAL B C   1 
ATOM   7904  O O   . VAL B 1 360 ? 130.268 123.279 147.494 1.00 43.69  ?  349 VAL B O   1 
ATOM   7905  C CB  . VAL B 1 360 ? 132.047 124.942 149.641 1.00 43.69  ?  349 VAL B CB  1 
ATOM   7906  C CG1 . VAL B 1 360 ? 132.513 123.497 149.581 1.00 43.69  ?  349 VAL B CG1 1 
ATOM   7907  C CG2 . VAL B 1 360 ? 133.233 125.874 149.635 1.00 43.69  ?  349 VAL B CG2 1 
ATOM   7908  N N   . ALA B 1 361 ? 128.999 124.212 149.073 1.00 43.12  ?  350 ALA B N   1 
ATOM   7909  C CA  . ALA B 1 361 ? 127.951 123.232 148.986 1.00 43.12  ?  350 ALA B CA  1 
ATOM   7910  C C   . ALA B 1 361 ? 127.293 123.302 147.620 1.00 43.12  ?  350 ALA B C   1 
ATOM   7911  O O   . ALA B 1 361 ? 126.979 122.289 147.043 1.00 43.12  ?  350 ALA B O   1 
ATOM   7912  C CB  . ALA B 1 361 ? 126.938 123.452 150.091 1.00 43.12  ?  350 ALA B CB  1 
ATOM   7913  N N   . PHE B 1 362 ? 127.023 124.506 147.142 1.00 43.07  ?  351 PHE B N   1 
ATOM   7914  C CA  . PHE B 1 362 ? 126.459 124.690 145.823 1.00 43.07  ?  351 PHE B CA  1 
ATOM   7915  C C   . PHE B 1 362 ? 127.397 124.357 144.667 1.00 43.07  ?  351 PHE B C   1 
ATOM   7916  O O   . PHE B 1 362 ? 126.994 123.764 143.692 1.00 43.07  ?  351 PHE B O   1 
ATOM   7917  C CB  . PHE B 1 362 ? 125.877 126.087 145.650 1.00 43.07  ?  351 PHE B CB  1 
ATOM   7918  C CG  . PHE B 1 362 ? 125.318 126.330 144.288 1.00 43.07  ?  351 PHE B CG  1 
ATOM   7919  C CD1 . PHE B 1 362 ? 124.305 125.536 143.793 1.00 43.07  ?  351 PHE B CD1 1 
ATOM   7920  C CD2 . PHE B 1 362 ? 125.811 127.337 143.499 1.00 43.07  ?  351 PHE B CD2 1 
ATOM   7921  C CE1 . PHE B 1 362 ? 123.800 125.739 142.541 1.00 43.07  ?  351 PHE B CE1 1 
ATOM   7922  C CE2 . PHE B 1 362 ? 125.294 127.551 142.246 1.00 43.07  ?  351 PHE B CE2 1 
ATOM   7923  C CZ  . PHE B 1 362 ? 124.291 126.749 141.766 1.00 43.07  ?  351 PHE B CZ  1 
ATOM   7924  N N   . ALA B 1 363 ? 128.650 124.760 144.782 1.00 43.93  ?  352 ALA B N   1 
ATOM   7925  C CA  . ALA B 1 363 ? 129.633 124.505 143.754 1.00 43.93  ?  352 ALA B CA  1 
ATOM   7926  C C   . ALA B 1 363 ? 129.852 123.017 143.578 1.00 43.93  ?  352 ALA B C   1 
ATOM   7927  O O   . ALA B 1 363 ? 129.976 122.539 142.469 1.00 43.93  ?  352 ALA B O   1 
ATOM   7928  C CB  . ALA B 1 363 ? 130.935 125.194 144.088 1.00 43.93  ?  352 ALA B CB  1 
ATOM   7929  N N   . VAL B 1 364 ? 129.908 122.299 144.688 1.00 44.06  ?  353 VAL B N   1 
ATOM   7930  C CA  . VAL B 1 364 ? 130.114 120.866 144.686 1.00 44.06  ?  353 VAL B CA  1 
ATOM   7931  C C   . VAL B 1 364 ? 128.876 120.127 144.207 1.00 44.06  ?  353 VAL B C   1 
ATOM   7932  O O   . VAL B 1 364 ? 128.980 119.238 143.405 1.00 44.06  ?  353 VAL B O   1 
ATOM   7933  C CB  . VAL B 1 364 ? 130.559 120.359 146.082 1.00 44.06  ?  353 VAL B CB  1 
ATOM   7934  C CG1 . VAL B 1 364 ? 130.414 118.858 146.210 1.00 44.06  ?  353 VAL B CG1 1 
ATOM   7935  C CG2 . VAL B 1 364 ? 131.978 120.783 146.372 1.00 44.06  ?  353 VAL B CG2 1 
ATOM   7936  N N   . ALA B 1 365 ? 127.710 120.486 144.707 1.00 45.09  ?  354 ALA B N   1 
ATOM   7937  C CA  . ALA B 1 365 ? 126.488 119.833 144.300 1.00 45.09  ?  354 ALA B CA  1 
ATOM   7938  C C   . ALA B 1 365 ? 126.187 120.042 142.828 1.00 45.09  ?  354 ALA B C   1 
ATOM   7939  O O   . ALA B 1 365 ? 125.807 119.116 142.151 1.00 45.09  ?  354 ALA B O   1 
ATOM   7940  C CB  . ALA B 1 365 ? 125.319 120.260 145.170 1.00 45.09  ?  354 ALA B CB  1 
ATOM   7941  N N   . PHE B 1 366 ? 126.378 121.259 142.342 1.00 45.52  ?  355 PHE B N   1 
ATOM   7942  C CA  . PHE B 1 366 ? 126.137 121.577 140.952 1.00 45.52  ?  355 PHE B CA  1 
ATOM   7943  C C   . PHE B 1 366 ? 127.081 120.829 140.022 1.00 45.52  ?  355 PHE B C   1 
ATOM   7944  O O   . PHE B 1 366 ? 126.694 120.345 138.974 1.00 45.52  ?  355 PHE B O   1 
ATOM   7945  C CB  . PHE B 1 366 ? 126.197 123.086 140.718 1.00 45.52  ?  355 PHE B CB  1 
ATOM   7946  C CG  . PHE B 1 366 ? 125.692 123.491 139.377 1.00 45.52  ?  355 PHE B CG  1 
ATOM   7947  C CD1 . PHE B 1 366 ? 126.563 123.795 138.354 1.00 45.52  ?  355 PHE B CD1 1 
ATOM   7948  C CD2 . PHE B 1 366 ? 124.342 123.508 139.123 1.00 45.52  ?  355 PHE B CD2 1 
ATOM   7949  C CE1 . PHE B 1 366 ? 126.093 124.122 137.113 1.00 45.52  ?  355 PHE B CE1 1 
ATOM   7950  C CE2 . PHE B 1 366 ? 123.863 123.850 137.884 1.00 45.52  ?  355 PHE B CE2 1 
ATOM   7951  C CZ  . PHE B 1 366 ? 124.740 124.156 136.879 1.00 45.52  ?  355 PHE B CZ  1 
ATOM   7952  N N   . SER B 1 367 ? 128.332 120.745 140.426 1.00 47.12  ?  356 SER B N   1 
ATOM   7953  C CA  . SER B 1 367 ? 129.332 120.040 139.665 1.00 47.12  ?  356 SER B CA  1 
ATOM   7954  C C   . SER B 1 367 ? 129.036 118.545 139.539 1.00 47.12  ?  356 SER B C   1 
ATOM   7955  O O   . SER B 1 367 ? 129.213 117.969 138.478 1.00 47.12  ?  356 SER B O   1 
ATOM   7956  C CB  . SER B 1 367 ? 130.684 120.259 140.312 1.00 47.12  ?  356 SER B CB  1 
ATOM   7957  O OG  . SER B 1 367 ? 131.646 119.403 139.769 1.00 47.12  ?  356 SER B OG  1 
ATOM   7958  N N   . VAL B 1 368 ? 128.634 117.908 140.631 1.00 47.73  ?  357 VAL B N   1 
ATOM   7959  C CA  . VAL B 1 368 ? 128.265 116.508 140.606 1.00 47.73  ?  357 VAL B CA  1 
ATOM   7960  C C   . VAL B 1 368 ? 126.985 116.309 139.798 1.00 47.73  ?  357 VAL B C   1 
ATOM   7961  O O   . VAL B 1 368 ? 126.878 115.397 139.012 1.00 47.73  ?  357 VAL B O   1 
ATOM   7962  C CB  . VAL B 1 368 ? 128.145 115.932 142.034 1.00 47.73  ?  357 VAL B CB  1 
ATOM   7963  C CG1 . VAL B 1 368 ? 127.620 114.515 142.020 1.00 47.73  ?  357 VAL B CG1 1 
ATOM   7964  C CG2 . VAL B 1 368 ? 129.477 116.000 142.745 1.00 47.73  ?  357 VAL B CG2 1 
ATOM   7965  N N   . ALA B 1 369 ? 126.028 117.203 139.979 1.00 48.35  ?  358 ALA B N   1 
ATOM   7966  C CA  . ALA B 1 369 ? 124.755 117.131 139.294 1.00 48.35  ?  358 ALA B CA  1 
ATOM   7967  C C   . ALA B 1 369 ? 124.907 117.259 137.788 1.00 48.35  ?  358 ALA B C   1 
ATOM   7968  O O   . ALA B 1 369 ? 124.204 116.605 137.044 1.00 48.35  ?  358 ALA B O   1 
ATOM   7969  C CB  . ALA B 1 369 ? 123.792 118.167 139.830 1.00 48.35  ?  358 ALA B CB  1 
ATOM   7970  N N   . SER B 1 370 ? 125.821 118.126 137.368 1.00 47.89  ?  359 SER B N   1 
ATOM   7971  C CA  . SER B 1 370 ? 126.135 118.409 135.982 1.00 47.89  ?  359 SER B CA  1 
ATOM   7972  C C   . SER B 1 370 ? 126.670 117.213 135.253 1.00 47.89  ?  359 SER B C   1 
ATOM   7973  O O   . SER B 1 370 ? 126.403 117.034 134.096 1.00 47.89  ?  359 SER B O   1 
ATOM   7974  C CB  . SER B 1 370 ? 127.176 119.499 135.906 1.00 47.89  ?  359 SER B CB  1 
ATOM   7975  O OG  . SER B 1 370 ? 126.608 120.749 136.119 1.00 47.89  ?  359 SER B OG  1 
ATOM   7976  N N   . VAL B 1 371 ? 127.496 116.434 135.920 1.00 48.76  ?  360 VAL B N   1 
ATOM   7977  C CA  . VAL B 1 371 ? 128.032 115.241 135.328 1.00 48.76  ?  360 VAL B CA  1 
ATOM   7978  C C   . VAL B 1 371 ? 126.885 114.299 135.002 1.00 48.76  ?  360 VAL B C   1 
ATOM   7979  O O   . VAL B 1 371 ? 126.892 113.663 133.978 1.00 48.76  ?  360 VAL B O   1 
ATOM   7980  C CB  . VAL B 1 371 ? 129.044 114.545 136.265 1.00 48.76  ?  360 VAL B CB  1 
ATOM   7981  C CG1 . VAL B 1 371 ? 129.232 113.090 135.894 1.00 48.76  ?  360 VAL B CG1 1 
ATOM   7982  C CG2 . VAL B 1 371 ? 130.366 115.261 136.253 1.00 48.76  ?  360 VAL B CG2 1 
ATOM   7983  N N   . TYR B 1 372 ? 125.878 114.219 135.850 1.00 51.05  ?  361 TYR B N   1 
ATOM   7984  C CA  . TYR B 1 372 ? 124.795 113.295 135.538 1.00 51.05  ?  361 TYR B CA  1 
ATOM   7985  C C   . TYR B 1 372 ? 123.781 113.894 134.582 1.00 51.05  ?  361 TYR B C   1 
ATOM   7986  O O   . TYR B 1 372 ? 123.159 113.174 133.816 1.00 51.05  ?  361 TYR B O   1 
ATOM   7987  C CB  . TYR B 1 372 ? 124.118 112.814 136.817 1.00 51.05  ?  361 TYR B CB  1 
ATOM   7988  C CG  . TYR B 1 372 ? 125.061 112.108 137.751 1.00 51.05  ?  361 TYR B CG  1 
ATOM   7989  C CD1 . TYR B 1 372 ? 125.732 110.965 137.350 1.00 51.05  ?  361 TYR B CD1 1 
ATOM   7990  C CD2 . TYR B 1 372 ? 125.280 112.582 139.035 1.00 51.05  ?  361 TYR B CD2 1 
ATOM   7991  C CE1 . TYR B 1 372 ? 126.601 110.314 138.198 1.00 51.05  ?  361 TYR B CE1 1 
ATOM   7992  C CE2 . TYR B 1 372 ? 126.146 111.936 139.893 1.00 51.05  ?  361 TYR B CE2 1 
ATOM   7993  C CZ  . TYR B 1 372 ? 126.802 110.802 139.469 1.00 51.05  ?  361 TYR B CZ  1 
ATOM   7994  O OH  . TYR B 1 372 ? 127.664 110.154 140.316 1.00 51.05  ?  361 TYR B OH  1 
ATOM   7995  N N   . SER B 1 373 ? 123.617 115.208 134.611 1.00 51.52  ?  362 SER B N   1 
ATOM   7996  C CA  . SER B 1 373 ? 122.726 115.859 133.664 1.00 51.52  ?  362 SER B CA  1 
ATOM   7997  C C   . SER B 1 373 ? 123.307 115.783 132.251 1.00 51.52  ?  362 SER B C   1 
ATOM   7998  O O   . SER B 1 373 ? 122.568 115.527 131.312 1.00 51.52  ?  362 SER B O   1 
ATOM   7999  C CB  . SER B 1 373 ? 122.443 117.303 134.086 1.00 51.52  ?  362 SER B CB  1 
ATOM   8000  O OG  . SER B 1 373 ? 123.620 118.086 134.072 1.00 51.52  ?  362 SER B OG  1 
ATOM   8001  N N   . LEU B 1 374 ? 124.613 116.007 132.083 1.00 53.29  ?  363 LEU B N   1 
ATOM   8002  C CA  . LEU B 1 374 ? 125.212 115.836 130.768 1.00 53.29  ?  363 LEU B CA  1 
ATOM   8003  C C   . LEU B 1 374 ? 125.268 114.365 130.382 1.00 53.29  ?  363 LEU B C   1 
ATOM   8004  O O   . LEU B 1 374 ? 125.084 114.018 129.211 1.00 53.29  ?  363 LEU B O   1 
ATOM   8005  C CB  . LEU B 1 374 ? 126.607 116.457 130.747 1.00 53.29  ?  363 LEU B CB  1 
ATOM   8006  C CG  . LEU B 1 374 ? 127.399 116.324 129.451 1.00 53.29  ?  363 LEU B CG  1 
ATOM   8007  C CD1 . LEU B 1 374 ? 126.788 117.182 128.361 1.00 53.29  ?  363 LEU B CD1 1 
ATOM   8008  C CD2 . LEU B 1 374 ? 128.847 116.699 129.681 1.00 53.29  ?  363 LEU B CD2 1 
ATOM   8009  N N   . LYS B 1 375 ? 125.512 113.483 131.356 1.00 54.01  ?  364 LYS B N   1 
ATOM   8010  C CA  . LYS B 1 375 ? 125.579 112.057 131.048 1.00 54.01  ?  364 LYS B CA  1 
ATOM   8011  C C   . LYS B 1 375 ? 124.225 111.504 130.621 1.00 54.01  ?  364 LYS B C   1 
ATOM   8012  O O   . LYS B 1 375 ? 124.157 110.613 129.765 1.00 54.01  ?  364 LYS B O   1 
ATOM   8013  C CB  . LYS B 1 375 ? 126.115 111.286 132.252 1.00 54.01  ?  364 LYS B CB  1 
ATOM   8014  C CG  . LYS B 1 375 ? 126.234 109.791 132.034 1.00 54.01  ?  364 LYS B CG  1 
ATOM   8015  C CD  . LYS B 1 375 ? 126.981 109.137 133.173 1.00 54.01  ?  364 LYS B CD  1 
ATOM   8016  C CE  . LYS B 1 375 ? 127.295 107.689 132.869 1.00 54.01  ?  364 LYS B CE  1 
ATOM   8017  N NZ  . LYS B 1 375 ? 126.251 106.768 133.380 1.00 54.01  1  364 LYS B NZ  1 
ATOM   8018  N N   . TYR B 1 376 ? 123.134 112.002 131.201 1.00 54.28  ?  365 TYR B N   1 
ATOM   8019  C CA  . TYR B 1 376 ? 121.809 111.454 130.930 1.00 54.28  ?  365 TYR B CA  1 
ATOM   8020  C C   . TYR B 1 376 ? 120.894 112.420 130.190 1.00 54.28  ?  365 TYR B C   1 
ATOM   8021  O O   . TYR B 1 376 ? 119.727 112.089 129.957 1.00 54.28  ?  365 TYR B O   1 
ATOM   8022  C CB  . TYR B 1 376 ? 121.154 111.000 132.233 1.00 54.28  ?  365 TYR B CB  1 
ATOM   8023  C CG  . TYR B 1 376 ? 121.918 109.901 132.922 1.00 54.28  ?  365 TYR B CG  1 
ATOM   8024  C CD1 . TYR B 1 376 ? 122.822 110.193 133.925 1.00 54.28  ?  365 TYR B CD1 1 
ATOM   8025  C CD2 . TYR B 1 376 ? 121.745 108.577 132.560 1.00 54.28  ?  365 TYR B CD2 1 
ATOM   8026  C CE1 . TYR B 1 376 ? 123.526 109.203 134.552 1.00 54.28  ?  365 TYR B CE1 1 
ATOM   8027  C CE2 . TYR B 1 376 ? 122.448 107.578 133.182 1.00 54.28  ?  365 TYR B CE2 1 
ATOM   8028  C CZ  . TYR B 1 376 ? 123.336 107.898 134.179 1.00 54.28  ?  365 TYR B CZ  1 
ATOM   8029  O OH  . TYR B 1 376 ? 124.045 106.911 134.811 1.00 54.28  ?  365 TYR B OH  1 
ATOM   8030  N N   . ASP B 1 377 ? 121.387 113.602 129.826 1.00 56.25  ?  366 ASP B N   1 
ATOM   8031  C CA  . ASP B 1 377 ? 120.709 114.497 128.889 1.00 56.25  ?  366 ASP B CA  1 
ATOM   8032  C C   . ASP B 1 377 ? 119.359 114.978 129.426 1.00 56.25  ?  366 ASP B C   1 
ATOM   8033  O O   . ASP B 1 377 ? 118.310 114.789 128.809 1.00 56.25  ?  366 ASP B O   1 
ATOM   8034  C CB  . ASP B 1 377 ? 120.544 113.815 127.528 1.00 56.25  ?  366 ASP B CB  1 
ATOM   8035  C CG  . ASP B 1 377 ? 120.561 114.795 126.379 1.00 56.25  ?  366 ASP B CG  1 
ATOM   8036  O OD1 . ASP B 1 377 ? 121.641 114.989 125.783 1.00 56.25  ?  366 ASP B OD1 1 
ATOM   8037  O OD2 . ASP B 1 377 ? 119.496 115.372 126.077 1.00 56.25  -1 366 ASP B OD2 1 
ATOM   8038  N N   . TYR B 1 378 ? 119.400 115.616 130.591 1.00 52.23  ?  367 TYR B N   1 
ATOM   8039  C CA  . TYR B 1 378 ? 118.236 116.302 131.123 1.00 52.23  ?  367 TYR B CA  1 
ATOM   8040  C C   . TYR B 1 378 ? 118.661 117.680 131.607 1.00 52.23  ?  367 TYR B C   1 
ATOM   8041  O O   . TYR B 1 378 ? 119.815 117.868 132.010 1.00 52.23  ?  367 TYR B O   1 
ATOM   8042  C CB  . TYR B 1 378 ? 117.555 115.516 132.261 1.00 52.23  ?  367 TYR B CB  1 
ATOM   8043  C CG  . TYR B 1 378 ? 118.420 115.175 133.457 1.00 52.23  ?  367 TYR B CG  1 
ATOM   8044  C CD1 . TYR B 1 378 ? 119.018 113.931 133.573 1.00 52.23  ?  367 TYR B CD1 1 
ATOM   8045  C CD2 . TYR B 1 378 ? 118.603 116.084 134.487 1.00 52.23  ?  367 TYR B CD2 1 
ATOM   8046  C CE1 . TYR B 1 378 ? 119.791 113.616 134.662 1.00 52.23  ?  367 TYR B CE1 1 
ATOM   8047  C CE2 . TYR B 1 378 ? 119.377 115.774 135.578 1.00 52.23  ?  367 TYR B CE2 1 
ATOM   8048  C CZ  . TYR B 1 378 ? 119.966 114.539 135.662 1.00 52.23  ?  367 TYR B CZ  1 
ATOM   8049  O OH  . TYR B 1 378 ? 120.739 114.229 136.751 1.00 52.23  ?  367 TYR B OH  1 
ATOM   8050  N N   . PRO B 1 379 ? 117.766 118.662 131.559 1.00 52.01  ?  368 PRO B N   1 
ATOM   8051  C CA  . PRO B 1 379 ? 118.134 120.017 131.976 1.00 52.01  ?  368 PRO B CA  1 
ATOM   8052  C C   . PRO B 1 379 ? 118.310 120.132 133.481 1.00 52.01  ?  368 PRO B C   1 
ATOM   8053  O O   . PRO B 1 379 ? 117.697 119.405 134.265 1.00 52.01  ?  368 PRO B O   1 
ATOM   8054  C CB  . PRO B 1 379 ? 116.950 120.861 131.498 1.00 52.01  ?  368 PRO B CB  1 
ATOM   8055  C CG  . PRO B 1 379 ? 115.813 119.919 131.504 1.00 52.01  ?  368 PRO B CG  1 
ATOM   8056  C CD  . PRO B 1 379 ? 116.381 118.605 131.064 1.00 52.01  ?  368 PRO B CD  1 
ATOM   8057  N N   . LEU B 1 380 ? 119.158 121.076 133.878 1.00 50.60  ?  369 LEU B N   1 
ATOM   8058  C CA  . LEU B 1 380 ? 119.502 121.295 135.277 1.00 50.60  ?  369 LEU B CA  1 
ATOM   8059  C C   . LEU B 1 380 ? 119.446 122.788 135.566 1.00 50.60  ?  369 LEU B C   1 
ATOM   8060  O O   . LEU B 1 380 ? 120.292 123.550 135.086 1.00 50.60  ?  369 LEU B O   1 
ATOM   8061  C CB  . LEU B 1 380 ? 120.886 120.730 135.585 1.00 50.60  ?  369 LEU B CB  1 
ATOM   8062  C CG  . LEU B 1 380 ? 121.257 120.568 137.052 1.00 50.60  ?  369 LEU B CG  1 
ATOM   8063  C CD1 . LEU B 1 380 ? 120.716 119.265 137.579 1.00 50.60  ?  369 LEU B CD1 1 
ATOM   8064  C CD2 . LEU B 1 380 ? 122.756 120.631 137.202 1.00 50.60  ?  369 LEU B CD2 1 
ATOM   8065  N N   . ASP B 1 381 ? 118.555 123.179 136.476 1.00 51.89  ?  370 ASP B N   1 
ATOM   8066  C CA  . ASP B 1 381 ? 118.432 124.584 136.870 1.00 51.89  ?  370 ASP B CA  1 
ATOM   8067  C C   . ASP B 1 381 ? 119.167 124.914 138.165 1.00 51.89  ?  370 ASP B C   1 
ATOM   8068  O O   . ASP B 1 381 ? 118.767 124.460 139.231 1.00 51.89  ?  370 ASP B O   1 
ATOM   8069  C CB  . ASP B 1 381 ? 116.953 124.936 137.034 1.00 51.89  ?  370 ASP B CB  1 
ATOM   8070  C CG  . ASP B 1 381 ? 116.732 126.363 137.503 1.00 51.89  ?  370 ASP B CG  1 
ATOM   8071  O OD1 . ASP B 1 381 ? 117.648 127.200 137.365 1.00 51.89  ?  370 ASP B OD1 1 
ATOM   8072  O OD2 . ASP B 1 381 ? 115.628 126.651 138.002 1.00 51.89  -1 370 ASP B OD2 1 
ATOM   8073  N N   . GLY B 1 382 ? 120.213 125.726 138.087 1.00 48.79  ?  371 GLY B N   1 
ATOM   8074  C CA  . GLY B 1 382 ? 120.967 126.105 139.267 1.00 48.79  ?  371 GLY B CA  1 
ATOM   8075  C C   . GLY B 1 382 ? 120.206 126.886 140.314 1.00 48.79  ?  371 GLY B C   1 
ATOM   8076  O O   . GLY B 1 382 ? 120.418 126.690 141.506 1.00 48.79  ?  371 GLY B O   1 
ATOM   8077  N N   . ASN B 1 383 ? 119.330 127.783 139.881 1.00 48.37  ?  372 ASN B N   1 
ATOM   8078  C CA  . ASN B 1 383 ? 118.549 128.578 140.814 1.00 48.37  ?  372 ASN B CA  1 
ATOM   8079  C C   . ASN B 1 383 ? 117.653 127.698 141.662 1.00 48.37  ?  372 ASN B C   1 
ATOM   8080  O O   . ASN B 1 383 ? 117.552 127.892 142.867 1.00 48.37  ?  372 ASN B O   1 
ATOM   8081  C CB  . ASN B 1 383 ? 117.712 129.609 140.064 1.00 48.37  ?  372 ASN B CB  1 
ATOM   8082  C CG  . ASN B 1 383 ? 118.555 130.673 139.398 1.00 48.37  ?  372 ASN B CG  1 
ATOM   8083  O OD1 . ASN B 1 383 ? 119.646 130.991 139.858 1.00 48.37  ?  372 ASN B OD1 1 
ATOM   8084  N ND2 . ASN B 1 383 ? 118.042 131.240 138.316 1.00 48.37  ?  372 ASN B ND2 1 
ATOM   8085  N N   . GLN B 1 384 ? 117.011 126.721 141.038 1.00 49.81  ?  373 GLN B N   1 
ATOM   8086  C CA  . GLN B 1 384 ? 116.154 125.809 141.774 1.00 49.81  ?  373 GLN B CA  1 
ATOM   8087  C C   . GLN B 1 384 ? 117.001 124.958 142.705 1.00 49.81  ?  373 GLN B C   1 
ATOM   8088  O O   . GLN B 1 384 ? 116.554 124.605 143.786 1.00 49.81  ?  373 GLN B O   1 
ATOM   8089  C CB  . GLN B 1 384 ? 115.317 124.948 140.826 1.00 49.81  ?  373 GLN B CB  1 
ATOM   8090  C CG  . GLN B 1 384 ? 114.268 124.104 141.532 1.00 49.81  ?  373 GLN B CG  1 
ATOM   8091  C CD  . GLN B 1 384 ? 113.336 124.924 142.404 1.00 49.81  ?  373 GLN B CD  1 
ATOM   8092  O OE1 . GLN B 1 384 ? 113.187 126.128 142.214 1.00 49.81  ?  373 GLN B OE1 1 
ATOM   8093  N NE2 . GLN B 1 384 ? 112.696 124.270 143.361 1.00 49.81  ?  373 GLN B NE2 1 
ATOM   8094  N N   . GLU B 1 385 ? 118.218 124.631 142.292 1.00 48.63  ?  374 GLU B N   1 
ATOM   8095  C CA  . GLU B 1 385 ? 119.122 123.876 143.148 1.00 48.63  ?  374 GLU B CA  1 
ATOM   8096  C C   . GLU B 1 385 ? 119.432 124.645 144.410 1.00 48.63  ?  374 GLU B C   1 
ATOM   8097  O O   . GLU B 1 385 ? 119.360 124.097 145.495 1.00 48.63  ?  374 GLU B O   1 
ATOM   8098  C CB  . GLU B 1 385 ? 120.426 123.552 142.416 1.00 48.63  ?  374 GLU B CB  1 
ATOM   8099  C CG  . GLU B 1 385 ? 120.259 122.786 141.119 1.00 48.63  ?  374 GLU B CG  1 
ATOM   8100  C CD  . GLU B 1 385 ? 119.677 121.402 141.317 1.00 48.63  ?  374 GLU B CD  1 
ATOM   8101  O OE1 . GLU B 1 385 ? 120.417 120.421 141.111 1.00 48.63  ?  374 GLU B OE1 1 
ATOM   8102  O OE2 . GLU B 1 385 ? 118.485 121.292 141.675 1.00 48.63  -1 374 GLU B OE2 1 
ATOM   8103  N N   . LEU B 1 386 ? 119.767 125.918 144.270 1.00 43.69  ?  375 LEU B N   1 
ATOM   8104  C CA  . LEU B 1 386 ? 120.069 126.746 145.426 1.00 43.69  ?  375 LEU B CA  1 
ATOM   8105  C C   . LEU B 1 386 ? 118.868 126.839 146.352 1.00 43.69  ?  375 LEU B C   1 
ATOM   8106  O O   . LEU B 1 386 ? 119.025 126.870 147.564 1.00 43.69  ?  375 LEU B O   1 
ATOM   8107  C CB  . LEU B 1 386 ? 120.520 128.142 144.992 1.00 43.69  ?  375 LEU B CB  1 
ATOM   8108  C CG  . LEU B 1 386 ? 121.972 128.319 144.563 1.00 43.69  ?  375 LEU B CG  1 
ATOM   8109  C CD1 . LEU B 1 386 ? 122.148 129.619 143.799 1.00 43.69  ?  375 LEU B CD1 1 
ATOM   8110  C CD2 . LEU B 1 386 ? 122.876 128.275 145.784 1.00 43.69  ?  375 LEU B CD2 1 
ATOM   8111  N N   . ILE B 1 387 ? 117.673 126.888 145.786 1.00 45.59  ?  376 ILE B N   1 
ATOM   8112  C CA  . ILE B 1 387 ? 116.464 126.942 146.591 1.00 45.59  ?  376 ILE B CA  1 
ATOM   8113  C C   . ILE B 1 387 ? 116.239 125.622 147.284 1.00 45.59  ?  376 ILE B C   1 
ATOM   8114  O O   . ILE B 1 387 ? 115.916 125.583 148.462 1.00 45.59  ?  376 ILE B O   1 
ATOM   8115  C CB  . ILE B 1 387 ? 115.234 127.278 145.730 1.00 45.59  ?  376 ILE B CB  1 
ATOM   8116  C CG1 . ILE B 1 387 ? 115.347 128.705 145.188 1.00 45.59  ?  376 ILE B CG1 1 
ATOM   8117  C CG2 . ILE B 1 387 ? 113.952 127.106 146.526 1.00 45.59  ?  376 ILE B CG2 1 
ATOM   8118  C CD1 . ILE B 1 387 ? 114.230 129.095 144.249 1.00 45.59  ?  376 ILE B CD1 1 
ATOM   8119  N N   . ALA B 1 388 ? 116.404 124.538 146.548 1.00 44.90  ?  377 ALA B N   1 
ATOM   8120  C CA  . ALA B 1 388 ? 116.237 123.222 147.118 1.00 44.90  ?  377 ALA B CA  1 
ATOM   8121  C C   . ALA B 1 388 ? 117.351 122.944 148.095 1.00 44.90  ?  377 ALA B C   1 
ATOM   8122  O O   . ALA B 1 388 ? 117.107 122.384 149.156 1.00 44.90  ?  377 ALA B O   1 
ATOM   8123  C CB  . ALA B 1 388 ? 116.239 122.181 146.027 1.00 44.90  ?  377 ALA B CB  1 
ATOM   8124  N N   . LEU B 1 389 ? 118.576 123.336 147.765 1.00 44.28  ?  378 LEU B N   1 
ATOM   8125  C CA  . LEU B 1 389 ? 119.613 123.108 148.762 1.00 44.28  ?  378 LEU B CA  1 
ATOM   8126  C C   . LEU B 1 389 ? 119.467 124.060 149.940 1.00 44.28  ?  378 LEU B C   1 
ATOM   8127  O O   . LEU B 1 389 ? 119.692 123.667 151.088 1.00 44.28  ?  378 LEU B O   1 
ATOM   8128  C CB  . LEU B 1 389 ? 120.994 123.242 148.127 1.00 44.28  ?  378 LEU B CB  1 
ATOM   8129  C CG  . LEU B 1 389 ? 121.350 122.286 146.988 1.00 44.28  ?  378 LEU B CG  1 
ATOM   8130  C CD1 . LEU B 1 389 ? 122.633 122.742 146.332 1.00 44.28  ?  378 LEU B CD1 1 
ATOM   8131  C CD2 . LEU B 1 389 ? 121.472 120.853 147.465 1.00 44.28  ?  378 LEU B CD2 1 
ATOM   8132  N N   . GLY B 1 390 ? 118.969 125.270 149.716 1.00 44.26  ?  379 GLY B N   1 
ATOM   8133  C CA  . GLY B 1 390 ? 118.724 126.184 150.818 1.00 44.26  ?  379 GLY B CA  1 
ATOM   8134  C C   . GLY B 1 390 ? 117.649 125.697 151.770 1.00 44.26  ?  379 GLY B C   1 
ATOM   8135  O O   . GLY B 1 390 ? 117.862 125.663 152.972 1.00 44.26  ?  379 GLY B O   1 
ATOM   8136  N N   . LEU B 1 391 ? 116.499 125.307 151.241 1.00 44.72  ?  380 LEU B N   1 
ATOM   8137  C CA  . LEU B 1 391 ? 115.400 124.816 152.066 1.00 44.72  ?  380 LEU B CA  1 
ATOM   8138  C C   . LEU B 1 391 ? 115.755 123.545 152.821 1.00 44.72  ?  380 LEU B C   1 
ATOM   8139  O O   . LEU B 1 391 ? 115.358 123.384 153.967 1.00 44.72  ?  380 LEU B O   1 
ATOM   8140  C CB  . LEU B 1 391 ? 114.157 124.571 151.209 1.00 44.72  ?  380 LEU B CB  1 
ATOM   8141  C CG  . LEU B 1 391 ? 113.533 125.782 150.521 1.00 44.72  ?  380 LEU B CG  1 
ATOM   8142  C CD1 . LEU B 1 391 ? 112.496 125.343 149.499 1.00 44.72  ?  380 LEU B CD1 1 
ATOM   8143  C CD2 . LEU B 1 391 ? 112.923 126.716 151.553 1.00 44.72  ?  380 LEU B CD2 1 
ATOM   8144  N N   . GLY B 1 392 ? 116.488 122.642 152.184 1.00 43.72  ?  381 GLY B N   1 
ATOM   8145  C CA  . GLY B 1 392 ? 116.904 121.422 152.842 1.00 43.72  ?  381 GLY B CA  1 
ATOM   8146  C C   . GLY B 1 392 ? 117.793 121.698 154.021 1.00 43.72  ?  381 GLY B C   1 
ATOM   8147  O O   . GLY B 1 392 ? 117.652 121.068 155.063 1.00 43.72  ?  381 GLY B O   1 
ATOM   8148  N N   . ASN B 1 393 ? 118.701 122.649 153.867 1.00 43.72  ?  382 ASN B N   1 
ATOM   8149  C CA  . ASN B 1 393 ? 119.603 123.005 154.949 1.00 43.72  ?  382 ASN B CA  1 
ATOM   8150  C C   . ASN B 1 393 ? 118.899 123.723 156.089 1.00 43.72  ?  382 ASN B C   1 
ATOM   8151  O O   . ASN B 1 393 ? 119.250 123.543 157.247 1.00 43.72  ?  382 ASN B O   1 
ATOM   8152  C CB  . ASN B 1 393 ? 120.769 123.835 154.419 1.00 43.72  ?  382 ASN B CB  1 
ATOM   8153  C CG  . ASN B 1 393 ? 121.847 122.981 153.790 1.00 43.72  ?  382 ASN B CG  1 
ATOM   8154  O OD1 . ASN B 1 393 ? 122.490 123.388 152.823 1.00 43.72  ?  382 ASN B OD1 1 
ATOM   8155  N ND2 . ASN B 1 393 ? 122.045 121.787 154.330 1.00 43.72  ?  382 ASN B ND2 1 
ATOM   8156  N N   . ILE B 1 394 ? 117.900 124.527 155.769 1.00 44.19  ?  383 ILE B N   1 
ATOM   8157  C CA  . ILE B 1 394 ? 117.141 125.202 156.807 1.00 44.19  ?  383 ILE B CA  1 
ATOM   8158  C C   . ILE B 1 394 ? 116.373 124.196 157.654 1.00 44.19  ?  383 ILE B C   1 
ATOM   8159  O O   . ILE B 1 394 ? 116.406 124.265 158.871 1.00 44.19  ?  383 ILE B O   1 
ATOM   8160  C CB  . ILE B 1 394 ? 116.181 126.247 156.210 1.00 44.19  ?  383 ILE B CB  1 
ATOM   8161  C CG1 . ILE B 1 394 ? 116.979 127.337 155.492 1.00 44.19  ?  383 ILE B CG1 1 
ATOM   8162  C CG2 . ILE B 1 394 ? 115.300 126.845 157.294 1.00 44.19  ?  383 ILE B CG2 1 
ATOM   8163  C CD1 . ILE B 1 394 ? 116.129 128.288 154.679 1.00 44.19  ?  383 ILE B CD1 1 
ATOM   8164  N N   . VAL B 1 395 ? 115.702 123.251 157.014 1.00 45.75  ?  384 VAL B N   1 
ATOM   8165  C CA  . VAL B 1 395 ? 114.942 122.243 157.742 1.00 45.75  ?  384 VAL B CA  1 
ATOM   8166  C C   . VAL B 1 395 ? 115.899 121.382 158.531 1.00 45.75  ?  384 VAL B C   1 
ATOM   8167  O O   . VAL B 1 395 ? 115.581 120.931 159.622 1.00 45.75  ?  384 VAL B O   1 
ATOM   8168  C CB  . VAL B 1 395 ? 114.093 121.376 156.795 1.00 45.75  ?  384 VAL B CB  1 
ATOM   8169  C CG1 . VAL B 1 395 ? 113.403 120.258 157.558 1.00 45.75  ?  384 VAL B CG1 1 
ATOM   8170  C CG2 . VAL B 1 395 ? 113.081 122.237 156.058 1.00 45.75  ?  384 VAL B CG2 1 
ATOM   8171  N N   . CYS B 1 396 ? 117.077 121.147 157.974 1.00 47.81  ?  385 CYS B N   1 
ATOM   8172  C CA  . CYS B 1 396 ? 118.087 120.391 158.680 1.00 47.81  ?  385 CYS B CA  1 
ATOM   8173  C C   . CYS B 1 396 ? 118.640 121.185 159.869 1.00 47.81  ?  385 CYS B C   1 
ATOM   8174  O O   . CYS B 1 396 ? 118.688 120.657 160.970 1.00 47.81  ?  385 CYS B O   1 
ATOM   8175  C CB  . CYS B 1 396 ? 119.207 119.975 157.718 1.00 47.81  ?  385 CYS B CB  1 
ATOM   8176  S SG  . CYS B 1 396 ? 120.249 118.622 158.295 1.00 47.81  ?  385 CYS B SG  1 
ATOM   8177  N N   . GLY B 1 397 ? 119.069 122.435 159.662 1.00 47.66  ?  386 GLY B N   1 
ATOM   8178  C CA  . GLY B 1 397 ? 119.511 123.209 160.804 1.00 47.66  ?  386 GLY B CA  1 
ATOM   8179  C C   . GLY B 1 397 ? 118.416 123.471 161.815 1.00 47.66  ?  386 GLY B C   1 
ATOM   8180  O O   . GLY B 1 397 ? 118.689 123.573 163.013 1.00 47.66  ?  386 GLY B O   1 
ATOM   8181  N N   . VAL B 1 398 ? 117.169 123.595 161.361 1.00 49.25  ?  387 VAL B N   1 
ATOM   8182  C CA  . VAL B 1 398 ? 116.067 123.728 162.306 1.00 49.25  ?  387 VAL B CA  1 
ATOM   8183  C C   . VAL B 1 398 ? 115.926 122.462 163.130 1.00 49.25  ?  387 VAL B C   1 
ATOM   8184  O O   . VAL B 1 398 ? 115.705 122.522 164.345 1.00 49.25  ?  387 VAL B O   1 
ATOM   8185  C CB  . VAL B 1 398 ? 114.763 124.074 161.561 1.00 49.25  ?  387 VAL B CB  1 
ATOM   8186  C CG1 . VAL B 1 398 ? 113.555 123.663 162.372 1.00 49.25  ?  387 VAL B CG1 1 
ATOM   8187  C CG2 . VAL B 1 398 ? 114.717 125.553 161.261 1.00 49.25  ?  387 VAL B CG2 1 
ATOM   8188  N N   . PHE B 1 399 ? 116.086 121.298 162.501 1.00 50.13  ?  388 PHE B N   1 
ATOM   8189  C CA  . PHE B 1 399 ? 115.956 120.025 163.197 1.00 50.13  ?  388 PHE B CA  1 
ATOM   8190  C C   . PHE B 1 399 ? 117.303 119.448 163.622 1.00 50.13  ?  388 PHE B C   1 
ATOM   8191  O O   . PHE B 1 399 ? 117.471 118.225 163.642 1.00 50.13  ?  388 PHE B O   1 
ATOM   8192  C CB  . PHE B 1 399 ? 115.195 119.031 162.329 1.00 50.13  ?  388 PHE B CB  1 
ATOM   8193  C CG  . PHE B 1 399 ? 113.717 119.256 162.317 1.00 50.13  ?  388 PHE B CG  1 
ATOM   8194  C CD1 . PHE B 1 399 ? 113.134 120.047 161.348 1.00 50.13  ?  388 PHE B CD1 1 
ATOM   8195  C CD2 . PHE B 1 399 ? 112.911 118.679 163.278 1.00 50.13  ?  388 PHE B CD2 1 
ATOM   8196  C CE1 . PHE B 1 399 ? 111.776 120.255 161.336 1.00 50.13  ?  388 PHE B CE1 1 
ATOM   8197  C CE2 . PHE B 1 399 ? 111.554 118.885 163.270 1.00 50.13  ?  388 PHE B CE2 1 
ATOM   8198  C CZ  . PHE B 1 399 ? 110.986 119.674 162.299 1.00 50.13  ?  388 PHE B CZ  1 
ATOM   8199  N N   . ARG B 1 400 ? 118.265 120.312 163.950 1.00 53.01  ?  389 ARG B N   1 
ATOM   8200  C CA  . ARG B 1 400 ? 119.528 120.018 164.638 1.00 53.01  ?  389 ARG B CA  1 
ATOM   8201  C C   . ARG B 1 400 ? 120.614 119.391 163.770 1.00 53.01  ?  389 ARG B C   1 
ATOM   8202  O O   . ARG B 1 400 ? 121.696 119.112 164.294 1.00 53.01  ?  389 ARG B O   1 
ATOM   8203  C CB  . ARG B 1 400 ? 119.323 119.115 165.858 1.00 53.01  ?  389 ARG B CB  1 
ATOM   8204  C CG  . ARG B 1 400 ? 118.248 119.584 166.813 1.00 53.01  ?  389 ARG B CG  1 
ATOM   8205  C CD  . ARG B 1 400 ? 118.819 120.461 167.901 1.00 53.01  ?  389 ARG B CD  1 
ATOM   8206  N NE  . ARG B 1 400 ? 117.771 121.005 168.758 1.00 53.01  ?  389 ARG B NE  1 
ATOM   8207  C CZ  . ARG B 1 400 ? 117.468 120.532 169.960 1.00 53.01  ?  389 ARG B CZ  1 
ATOM   8208  N NH1 . ARG B 1 400 ? 116.499 121.094 170.668 1.00 53.01  1  389 ARG B NH1 1 
ATOM   8209  N NH2 . ARG B 1 400 ? 118.130 119.498 170.456 1.00 53.01  ?  389 ARG B NH2 1 
ATOM   8210  N N   . GLY B 1 401 ? 120.385 119.165 162.480 1.00 47.97  ?  390 GLY B N   1 
ATOM   8211  C CA  . GLY B 1 401 ? 121.419 118.671 161.596 1.00 47.97  ?  390 GLY B CA  1 
ATOM   8212  C C   . GLY B 1 401 ? 122.404 119.762 161.222 1.00 47.97  ?  390 GLY B C   1 
ATOM   8213  O O   . GLY B 1 401 ? 122.307 120.906 161.664 1.00 47.97  ?  390 GLY B O   1 
ATOM   8214  N N   . PHE B 1 402 ? 123.371 119.395 160.387 1.00 45.59  ?  391 PHE B N   1 
ATOM   8215  C CA  . PHE B 1 402 ? 124.339 120.359 159.884 1.00 45.59  ?  391 PHE B CA  1 
ATOM   8216  C C   . PHE B 1 402 ? 124.336 120.348 158.360 1.00 45.59  ?  391 PHE B C   1 
ATOM   8217  O O   . PHE B 1 402 ? 123.717 119.496 157.720 1.00 45.59  ?  391 PHE B O   1 
ATOM   8218  C CB  . PHE B 1 402 ? 125.752 120.107 160.431 1.00 45.59  ?  391 PHE B CB  1 
ATOM   8219  C CG  . PHE B 1 402 ? 126.244 118.708 160.243 1.00 45.59  ?  391 PHE B CG  1 
ATOM   8220  C CD1 . PHE B 1 402 ? 126.983 118.367 159.131 1.00 45.59  ?  391 PHE B CD1 1 
ATOM   8221  C CD2 . PHE B 1 402 ? 125.991 117.742 161.189 1.00 45.59  ?  391 PHE B CD2 1 
ATOM   8222  C CE1 . PHE B 1 402 ? 127.436 117.092 158.963 1.00 45.59  ?  391 PHE B CE1 1 
ATOM   8223  C CE2 . PHE B 1 402 ? 126.446 116.466 161.021 1.00 45.59  ?  391 PHE B CE2 1 
ATOM   8224  C CZ  . PHE B 1 402 ? 127.167 116.142 159.909 1.00 45.59  ?  391 PHE B CZ  1 
ATOM   8225  N N   . ALA B 1 403 ? 125.047 121.315 157.786 1.00 47.52  ?  392 ALA B N   1 
ATOM   8226  C CA  . ALA B 1 403 ? 124.953 121.588 156.358 1.00 47.52  ?  392 ALA B CA  1 
ATOM   8227  C C   . ALA B 1 403 ? 125.513 120.444 155.527 1.00 47.52  ?  392 ALA B C   1 
ATOM   8228  O O   . ALA B 1 403 ? 126.431 119.734 155.945 1.00 47.52  ?  392 ALA B O   1 
ATOM   8229  C CB  . ALA B 1 403 ? 125.690 122.883 156.022 1.00 47.52  ?  392 ALA B CB  1 
ATOM   8230  N N   . GLY B 1 404 ? 124.959 120.274 154.339 1.00 48.23  ?  393 GLY B N   1 
ATOM   8231  C CA  . GLY B 1 404 ? 125.449 119.252 153.445 1.00 48.23  ?  393 GLY B CA  1 
ATOM   8232  C C   . GLY B 1 404 ? 124.712 119.364 152.140 1.00 48.23  ?  393 GLY B C   1 
ATOM   8233  O O   . GLY B 1 404 ? 123.506 119.586 152.133 1.00 48.23  ?  393 GLY B O   1 
ATOM   8234  N N   . SER B 1 405 ? 125.417 119.211 151.031 1.00 48.25  ?  394 SER B N   1 
ATOM   8235  C CA  . SER B 1 405 ? 124.775 119.232 149.728 1.00 48.25  ?  394 SER B CA  1 
ATOM   8236  C C   . SER B 1 405 ? 124.778 117.834 149.145 1.00 48.25  ?  394 SER B C   1 
ATOM   8237  O O   . SER B 1 405 ? 123.741 117.200 149.045 1.00 48.25  ?  394 SER B O   1 
ATOM   8238  C CB  . SER B 1 405 ? 125.488 120.205 148.793 1.00 48.25  ?  394 SER B CB  1 
ATOM   8239  O OG  . SER B 1 405 ? 126.814 119.798 148.526 1.00 48.25  ?  394 SER B OG  1 
ATOM   8240  N N   . THR B 1 406 ? 125.945 117.351 148.759 1.00 48.50  ?  395 THR B N   1 
ATOM   8241  C CA  . THR B 1 406 ? 126.063 116.005 148.232 1.00 48.50  ?  395 THR B CA  1 
ATOM   8242  C C   . THR B 1 406 ? 127.481 115.506 148.322 1.00 48.50  ?  395 THR B C   1 
ATOM   8243  O O   . THR B 1 406 ? 128.417 116.293 148.267 1.00 48.50  ?  395 THR B O   1 
ATOM   8244  C CB  . THR B 1 406 ? 125.656 115.935 146.746 1.00 48.50  ?  395 THR B CB  1 
ATOM   8245  O OG1 . THR B 1 406 ? 125.823 114.597 146.266 1.00 48.50  ?  395 THR B OG1 1 
ATOM   8246  C CG2 . THR B 1 406 ? 126.516 116.860 145.913 1.00 48.50  ?  395 THR B CG2 1 
ATOM   8247  N N   . ALA B 1 407 ? 127.655 114.202 148.460 1.00 50.29  ?  396 ALA B N   1 
ATOM   8248  C CA  . ALA B 1 407 ? 128.991 113.640 148.420 1.00 50.29  ?  396 ALA B CA  1 
ATOM   8249  C C   . ALA B 1 407 ? 129.111 112.899 147.108 1.00 50.29  ?  396 ALA B C   1 
ATOM   8250  O O   . ALA B 1 407 ? 128.249 112.097 146.772 1.00 50.29  ?  396 ALA B O   1 
ATOM   8251  C CB  . ALA B 1 407 ? 129.245 112.713 149.590 1.00 50.29  ?  396 ALA B CB  1 
ATOM   8252  N N   . LEU B 1 408 ? 130.165 113.172 146.358 1.00 50.52  ?  397 LEU B N   1 
ATOM   8253  C CA  . LEU B 1 408 ? 130.384 112.497 145.089 1.00 50.52  ?  397 LEU B CA  1 
ATOM   8254  C C   . LEU B 1 408 ? 130.433 110.994 145.260 1.00 50.52  ?  397 LEU B C   1 
ATOM   8255  O O   . LEU B 1 408 ? 129.893 110.261 144.445 1.00 50.52  ?  397 LEU B O   1 
ATOM   8256  C CB  . LEU B 1 408 ? 131.686 112.985 144.463 1.00 50.52  ?  397 LEU B CB  1 
ATOM   8257  C CG  . LEU B 1 408 ? 132.105 112.345 143.141 1.00 50.52  ?  397 LEU B CG  1 
ATOM   8258  C CD1 . LEU B 1 408 ? 131.047 112.579 142.075 1.00 50.52  ?  397 LEU B CD1 1 
ATOM   8259  C CD2 . LEU B 1 408 ? 133.448 112.898 142.699 1.00 50.52  ?  397 LEU B CD2 1 
ATOM   8260  N N   . SER B 1 409 ? 131.080 110.533 146.321 1.00 52.21  ?  398 SER B N   1 
ATOM   8261  C CA  . SER B 1 409 ? 131.182 109.108 146.564 1.00 52.21  ?  398 SER B CA  1 
ATOM   8262  C C   . SER B 1 409 ? 129.804 108.495 146.707 1.00 52.21  ?  398 SER B C   1 
ATOM   8263  O O   . SER B 1 409 ? 129.501 107.509 146.056 1.00 52.21  ?  398 SER B O   1 
ATOM   8264  C CB  . SER B 1 409 ? 132.004 108.847 147.823 1.00 52.21  ?  398 SER B CB  1 
ATOM   8265  O OG  . SER B 1 409 ? 131.456 109.523 148.941 1.00 52.21  ?  398 SER B OG  1 
ATOM   8266  N N   . ARG B 1 410 ? 128.961 109.091 147.538 1.00 49.43  ?  399 ARG B N   1 
ATOM   8267  C CA  . ARG B 1 410 ? 127.622 108.572 147.752 1.00 49.43  ?  399 ARG B CA  1 
ATOM   8268  C C   . ARG B 1 410 ? 126.760 108.715 146.496 1.00 49.43  ?  399 ARG B C   1 
ATOM   8269  O O   . ARG B 1 410 ? 125.936 107.853 146.217 1.00 49.43  ?  399 ARG B O   1 
ATOM   8270  C CB  . ARG B 1 410 ? 126.985 109.273 148.952 1.00 49.43  ?  399 ARG B CB  1 
ATOM   8271  C CG  . ARG B 1 410 ? 125.744 108.609 149.507 1.00 49.43  ?  399 ARG B CG  1 
ATOM   8272  C CD  . ARG B 1 410 ? 125.199 109.374 150.704 1.00 49.43  ?  399 ARG B CD  1 
ATOM   8273  N NE  . ARG B 1 410 ? 124.955 110.783 150.407 1.00 49.43  ?  399 ARG B NE  1 
ATOM   8274  C CZ  . ARG B 1 410 ? 125.696 111.788 150.862 1.00 49.43  ?  399 ARG B CZ  1 
ATOM   8275  N NH1 . ARG B 1 410 ? 125.399 113.035 150.529 1.00 49.43  1  399 ARG B NH1 1 
ATOM   8276  N NH2 . ARG B 1 410 ? 126.726 111.551 151.659 1.00 49.43  ?  399 ARG B NH2 1 
ATOM   8277  N N   . SER B 1 411 ? 126.935 109.799 145.744 1.00 50.44  ?  400 SER B N   1 
ATOM   8278  C CA  . SER B 1 411 ? 126.199 109.968 144.488 1.00 50.44  ?  400 SER B CA  1 
ATOM   8279  C C   . SER B 1 411 ? 126.679 108.941 143.475 1.00 50.44  ?  400 SER B C   1 
ATOM   8280  O O   . SER B 1 411 ? 125.859 108.255 142.881 1.00 50.44  ?  400 SER B O   1 
ATOM   8281  C CB  . SER B 1 411 ? 126.299 111.401 143.957 1.00 50.44  ?  400 SER B CB  1 
ATOM   8282  O OG  . SER B 1 411 ? 125.781 112.322 144.895 1.00 50.44  ?  400 SER B OG  1 
ATOM   8283  N N   . ALA B 1 412 ? 127.988 108.838 143.246 1.00 51.11  ?  401 ALA B N   1 
ATOM   8284  C CA  . ALA B 1 412 ? 128.468 107.757 142.395 1.00 51.11  ?  401 ALA B CA  1 
ATOM   8285  C C   . ALA B 1 412 ? 127.893 106.418 142.828 1.00 51.11  ?  401 ALA B C   1 
ATOM   8286  O O   . ALA B 1 412 ? 127.579 105.574 141.986 1.00 51.11  ?  401 ALA B O   1 
ATOM   8287  C CB  . ALA B 1 412 ? 129.993 107.717 142.413 1.00 51.11  ?  401 ALA B CB  1 
ATOM   8288  N N   . VAL B 1 413 ? 127.761 106.194 144.137 1.00 52.41  ?  402 VAL B N   1 
ATOM   8289  C CA  . VAL B 1 413 ? 127.145 104.956 144.613 1.00 52.41  ?  402 VAL B CA  1 
ATOM   8290  C C   . VAL B 1 413 ? 125.675 104.901 144.213 1.00 52.41  ?  402 VAL B C   1 
ATOM   8291  O O   . VAL B 1 413 ? 125.124 103.824 143.956 1.00 52.41  ?  402 VAL B O   1 
ATOM   8292  C CB  . VAL B 1 413 ? 127.324 104.809 146.134 1.00 52.41  ?  402 VAL B CB  1 
ATOM   8293  C CG1 . VAL B 1 413 ? 126.738 103.501 146.609 1.00 52.41  ?  402 VAL B CG1 1 
ATOM   8294  C CG2 . VAL B 1 413 ? 128.789 104.843 146.492 1.00 52.41  ?  402 VAL B CG2 1 
ATOM   8295  N N   . GLN B 1 414 ? 125.015 106.059 144.156 1.00 52.82  ?  403 GLN B N   1 
ATOM   8296  C CA  . GLN B 1 414 ? 123.603 106.072 143.786 1.00 52.82  ?  403 GLN B CA  1 
ATOM   8297  C C   . GLN B 1 414 ? 123.419 105.868 142.292 1.00 52.82  ?  403 GLN B C   1 
ATOM   8298  O O   . GLN B 1 414 ? 122.507 105.155 141.865 1.00 52.82  ?  403 GLN B O   1 
ATOM   8299  C CB  . GLN B 1 414 ? 122.942 107.377 144.220 1.00 52.82  ?  403 GLN B CB  1 
ATOM   8300  C CG  . GLN B 1 414 ? 121.431 107.311 144.168 1.00 52.82  ?  403 GLN B CG  1 
ATOM   8301  C CD  . GLN B 1 414 ? 120.764 108.645 144.383 1.00 52.82  ?  403 GLN B CD  1 
ATOM   8302  O OE1 . GLN B 1 414 ? 121.164 109.417 145.245 1.00 52.82  ?  403 GLN B OE1 1 
ATOM   8303  N NE2 . GLN B 1 414 ? 119.731 108.921 143.600 1.00 52.82  ?  403 GLN B NE2 1 
ATOM   8304  N N   . GLU B 1 415 ? 124.267 106.494 141.477 1.00 56.88  ?  404 GLU B N   1 
ATOM   8305  C CA  . GLU B 1 415 ? 124.124 106.391 140.031 1.00 56.88  ?  404 GLU B CA  1 
ATOM   8306  C C   . GLU B 1 415 ? 124.613 105.046 139.512 1.00 56.88  ?  404 GLU B C   1 
ATOM   8307  O O   . GLU B 1 415 ? 124.005 104.470 138.603 1.00 56.88  ?  404 GLU B O   1 
ATOM   8308  C CB  . GLU B 1 415 ? 124.880 107.531 139.352 1.00 56.88  ?  404 GLU B CB  1 
ATOM   8309  C CG  . GLU B 1 415 ? 124.819 107.507 137.836 1.00 56.88  ?  404 GLU B CG  1 
ATOM   8310  C CD  . GLU B 1 415 ? 126.084 106.958 137.201 1.00 56.88  ?  404 GLU B CD  1 
ATOM   8311  O OE1 . GLU B 1 415 ? 127.164 107.062 137.819 1.00 56.88  ?  404 GLU B OE1 1 
ATOM   8312  O OE2 . GLU B 1 415 ? 125.998 106.424 136.078 1.00 56.88  -1 404 GLU B OE2 1 
ATOM   8313  N N   . SER B 1 416 ? 125.703 104.531 140.073 1.00 58.60  ?  405 SER B N   1 
ATOM   8314  C CA  . SER B 1 416 ? 126.290 103.273 139.644 1.00 58.60  ?  405 SER B CA  1 
ATOM   8315  C C   . SER B 1 416 ? 125.429 102.065 139.973 1.00 58.60  ?  405 SER B C   1 
ATOM   8316  O O   . SER B 1 416 ? 125.606 101.015 139.351 1.00 58.60  ?  405 SER B O   1 
ATOM   8317  C CB  . SER B 1 416 ? 127.666 103.103 140.288 1.00 58.60  ?  405 SER B CB  1 
ATOM   8318  O OG  . SER B 1 416 ? 128.029 101.737 140.348 1.00 58.60  ?  405 SER B OG  1 
ATOM   8319  N N   . THR B 1 417 ? 124.510 102.217 140.953 1.00 57.71  ?  406 THR B N   1 
ATOM   8320  C CA  . THR B 1 417 ? 123.634 101.111 141.387 1.00 57.71  ?  406 THR B CA  1 
ATOM   8321  C C   . THR B 1 417 ? 122.262 101.150 140.726 1.00 57.71  ?  406 THR B C   1 
ATOM   8322  O O   . THR B 1 417 ? 121.356 100.429 141.127 1.00 57.71  ?  406 THR B O   1 
ATOM   8323  C CB  . THR B 1 417 ? 123.485 101.081 142.925 1.00 57.71  ?  406 THR B CB  1 
ATOM   8324  O OG1 . THR B 1 417 ? 124.764 101.278 143.536 1.00 57.71  ?  406 THR B OG1 1 
ATOM   8325  C CG2 . THR B 1 417 ? 122.924 99.751  143.394 1.00 57.71  ?  406 THR B CG2 1 
ATOM   8326  N N   . GLY B 1 418 ? 122.090 101.988 139.720 1.00 57.47  ?  407 GLY B N   1 
ATOM   8327  C CA  . GLY B 1 418 ? 120.860 102.027 138.965 1.00 57.47  ?  407 GLY B CA  1 
ATOM   8328  C C   . GLY B 1 418 ? 119.949 103.192 139.267 1.00 57.47  ?  407 GLY B C   1 
ATOM   8329  O O   . GLY B 1 418 ? 118.784 103.156 138.866 1.00 57.47  ?  407 GLY B O   1 
ATOM   8330  N N   . GLY B 1 419 ? 120.434 104.216 139.959 1.00 57.54  ?  408 GLY B N   1 
ATOM   8331  C CA  . GLY B 1 419 ? 119.607 105.356 140.293 1.00 57.54  ?  408 GLY B CA  1 
ATOM   8332  C C   . GLY B 1 419 ? 119.030 106.029 139.069 1.00 57.54  ?  408 GLY B C   1 
ATOM   8333  O O   . GLY B 1 419 ? 119.770 106.551 138.234 1.00 57.54  ?  408 GLY B O   1 
ATOM   8334  N N   . LYS B 1 420 ? 117.706 106.010 138.951 1.00 58.11  ?  409 LYS B N   1 
ATOM   8335  C CA  . LYS B 1 420 ? 116.999 106.569 137.807 1.00 58.11  ?  409 LYS B CA  1 
ATOM   8336  C C   . LYS B 1 420 ? 116.312 107.889 138.109 1.00 58.11  ?  409 LYS B C   1 
ATOM   8337  O O   . LYS B 1 420 ? 116.366 108.807 137.293 1.00 58.11  ?  409 LYS B O   1 
ATOM   8338  C CB  . LYS B 1 420 ? 115.963 105.568 137.291 1.00 58.11  ?  409 LYS B CB  1 
ATOM   8339  C CG  . LYS B 1 420 ? 116.564 104.331 136.652 1.00 58.11  ?  409 LYS B CG  1 
ATOM   8340  C CD  . LYS B 1 420 ? 117.390 104.697 135.438 1.00 58.11  ?  409 LYS B CD  1 
ATOM   8341  C CE  . LYS B 1 420 ? 117.751 103.474 134.623 1.00 58.11  ?  409 LYS B CE  1 
ATOM   8342  N NZ  . LYS B 1 420 ? 118.679 102.569 135.349 1.00 58.11  1  409 LYS B NZ  1 
ATOM   8343  N N   . THR B 1 421 ? 115.658 108.001 139.262 1.00 57.42  ?  410 THR B N   1 
ATOM   8344  C CA  . THR B 1 421 ? 115.045 109.253 139.683 1.00 57.42  ?  410 THR B CA  1 
ATOM   8345  C C   . THR B 1 421 ? 115.489 109.598 141.094 1.00 57.42  ?  410 THR B C   1 
ATOM   8346  O O   . THR B 1 421 ? 116.376 108.942 141.648 1.00 57.42  ?  410 THR B O   1 
ATOM   8347  C CB  . THR B 1 421 ? 113.520 109.167 139.626 1.00 57.42  ?  410 THR B CB  1 
ATOM   8348  O OG1 . THR B 1 421 ? 113.103 107.855 140.014 1.00 57.42  ?  410 THR B OG1 1 
ATOM   8349  C CG2 . THR B 1 421 ? 113.029 109.451 138.230 1.00 57.42  ?  410 THR B CG2 1 
ATOM   8350  N N   . GLN B 1 422 ? 114.854 110.562 141.718 1.00 53.31  ?  411 GLN B N   1 
ATOM   8351  C CA  . GLN B 1 422 ? 115.180 110.924 143.098 1.00 53.31  ?  411 GLN B CA  1 
ATOM   8352  C C   . GLN B 1 422 ? 114.407 110.054 144.072 1.00 53.31  ?  411 GLN B C   1 
ATOM   8353  O O   . GLN B 1 422 ? 114.424 110.301 145.270 1.00 53.31  ?  411 GLN B O   1 
ATOM   8354  C CB  . GLN B 1 422 ? 114.928 112.412 143.358 1.00 53.31  ?  411 GLN B CB  1 
ATOM   8355  C CG  . GLN B 1 422 ? 115.802 113.008 144.446 1.00 53.31  ?  411 GLN B CG  1 
ATOM   8356  C CD  . GLN B 1 422 ? 117.282 112.845 144.158 1.00 53.31  ?  411 GLN B CD  1 
ATOM   8357  O OE1 . GLN B 1 422 ? 117.779 113.291 143.126 1.00 53.31  ?  411 GLN B OE1 1 
ATOM   8358  N NE2 . GLN B 1 422 ? 117.994 112.215 145.080 1.00 53.31  ?  411 GLN B NE2 1 
ATOM   8359  N N   . ILE B 1 423 ? 113.696 109.051 143.565 1.00 53.90  ?  412 ILE B N   1 
ATOM   8360  C CA  . ILE B 1 423 ? 113.074 108.090 144.465 1.00 53.90  ?  412 ILE B CA  1 
ATOM   8361  C C   . ILE B 1 423 ? 114.147 107.286 145.188 1.00 53.90  ?  412 ILE B C   1 
ATOM   8362  O O   . ILE B 1 423 ? 113.936 106.826 146.315 1.00 53.90  ?  412 ILE B O   1 
ATOM   8363  C CB  . ILE B 1 423 ? 112.104 107.189 143.682 1.00 53.90  ?  412 ILE B CB  1 
ATOM   8364  C CG1 . ILE B 1 423 ? 110.903 107.998 143.200 1.00 53.90  ?  412 ILE B CG1 1 
ATOM   8365  C CG2 . ILE B 1 423 ? 111.639 106.014 144.514 1.00 53.90  ?  412 ILE B CG2 1 
ATOM   8366  C CD1 . ILE B 1 423 ? 110.050 108.544 144.310 1.00 53.90  ?  412 ILE B CD1 1 
ATOM   8367  N N   . ALA B 1 424 ? 115.316 107.119 144.567 1.00 53.47  ?  413 ALA B N   1 
ATOM   8368  C CA  . ALA B 1 424 ? 116.440 106.504 145.260 1.00 53.47  ?  413 ALA B CA  1 
ATOM   8369  C C   . ALA B 1 424 ? 116.869 107.346 146.453 1.00 53.47  ?  413 ALA B C   1 
ATOM   8370  O O   . ALA B 1 424 ? 117.246 106.810 147.499 1.00 53.47  ?  413 ALA B O   1 
ATOM   8371  C CB  . ALA B 1 424 ? 117.602 106.302 144.293 1.00 53.47  ?  413 ALA B CB  1 
ATOM   8372  N N   . GLY B 1 425 ? 116.794 108.672 146.326 1.00 53.50  ?  414 GLY B N   1 
ATOM   8373  C CA  . GLY B 1 425 ? 117.062 109.527 147.469 1.00 53.50  ?  414 GLY B CA  1 
ATOM   8374  C C   . GLY B 1 425 ? 116.024 109.372 148.561 1.00 53.50  ?  414 GLY B C   1 
ATOM   8375  O O   . GLY B 1 425 ? 116.353 109.377 149.750 1.00 53.50  ?  414 GLY B O   1 
ATOM   8376  N N   . LEU B 1 426 ? 114.757 109.220 148.175 1.00 52.57  ?  415 LEU B N   1 
ATOM   8377  C CA  . LEU B 1 426 ? 113.705 108.983 149.156 1.00 52.57  ?  415 LEU B CA  1 
ATOM   8378  C C   . LEU B 1 426 ? 113.926 107.674 149.900 1.00 52.57  ?  415 LEU B C   1 
ATOM   8379  O O   . LEU B 1 426 ? 113.730 107.607 151.117 1.00 52.57  ?  415 LEU B O   1 
ATOM   8380  C CB  . LEU B 1 426 ? 112.343 108.983 148.466 1.00 52.57  ?  415 LEU B CB  1 
ATOM   8381  C CG  . LEU B 1 426 ? 111.170 108.426 149.270 1.00 52.57  ?  415 LEU B CG  1 
ATOM   8382  C CD1 . LEU B 1 426 ? 110.643 109.472 150.234 1.00 52.57  ?  415 LEU B CD1 1 
ATOM   8383  C CD2 . LEU B 1 426 ? 110.075 107.941 148.346 1.00 52.57  ?  415 LEU B CD2 1 
ATOM   8384  N N   . ILE B 1 427 ? 114.353 106.624 149.196 1.00 52.33  ?  416 ILE B N   1 
ATOM   8385  C CA  . ILE B 1 427 ? 114.551 105.345 149.866 1.00 52.33  ?  416 ILE B CA  1 
ATOM   8386  C C   . ILE B 1 427 ? 115.820 105.362 150.711 1.00 52.33  ?  416 ILE B C   1 
ATOM   8387  O O   . ILE B 1 427 ? 115.879 104.718 151.766 1.00 52.33  ?  416 ILE B O   1 
ATOM   8388  C CB  . ILE B 1 427 ? 114.547 104.204 148.835 1.00 52.33  ?  416 ILE B CB  1 
ATOM   8389  C CG1 . ILE B 1 427 ? 113.242 104.249 148.045 1.00 52.33  ?  416 ILE B CG1 1 
ATOM   8390  C CG2 . ILE B 1 427 ? 114.689 102.862 149.519 1.00 52.33  ?  416 ILE B CG2 1 
ATOM   8391  C CD1 . ILE B 1 427 ? 112.947 103.008 147.276 1.00 52.33  ?  416 ILE B CD1 1 
ATOM   8392  N N   . GLY B 1 428 ? 116.837 106.117 150.299 1.00 51.50  ?  417 GLY B N   1 
ATOM   8393  C CA  . GLY B 1 428 ? 117.988 106.308 151.164 1.00 51.50  ?  417 GLY B CA  1 
ATOM   8394  C C   . GLY B 1 428 ? 117.630 107.033 152.447 1.00 51.50  ?  417 GLY B C   1 
ATOM   8395  O O   . GLY B 1 428 ? 118.070 106.653 153.534 1.00 51.50  ?  417 GLY B O   1 
ATOM   8396  N N   . ALA B 1 429 ? 116.813 108.083 152.339 1.00 50.32  ?  418 ALA B N   1 
ATOM   8397  C CA  . ALA B 1 429 ? 116.356 108.778 153.534 1.00 50.32  ?  418 ALA B CA  1 
ATOM   8398  C C   . ALA B 1 429 ? 115.452 107.897 154.387 1.00 50.32  ?  418 ALA B C   1 
ATOM   8399  O O   . ALA B 1 429 ? 115.437 108.034 155.609 1.00 50.32  ?  418 ALA B O   1 
ATOM   8400  C CB  . ALA B 1 429 ? 115.637 110.066 153.148 1.00 50.32  ?  418 ALA B CB  1 
ATOM   8401  N N   . ILE B 1 430 ? 114.705 106.981 153.771 1.00 50.63  ?  419 ILE B N   1 
ATOM   8402  C CA  . ILE B 1 430 ? 113.902 106.043 154.550 1.00 50.63  ?  419 ILE B CA  1 
ATOM   8403  C C   . ILE B 1 430 ? 114.792 105.072 155.313 1.00 50.63  ?  419 ILE B C   1 
ATOM   8404  O O   . ILE B 1 430 ? 114.501 104.724 156.463 1.00 50.63  ?  419 ILE B O   1 
ATOM   8405  C CB  . ILE B 1 430 ? 112.911 105.304 153.631 1.00 50.63  ?  419 ILE B CB  1 
ATOM   8406  C CG1 . ILE B 1 430 ? 111.711 106.196 153.317 1.00 50.63  ?  419 ILE B CG1 1 
ATOM   8407  C CG2 . ILE B 1 430 ? 112.446 104.007 154.263 1.00 50.63  ?  419 ILE B CG2 1 
ATOM   8408  C CD1 . ILE B 1 430 ? 110.761 105.596 152.311 1.00 50.63  ?  419 ILE B CD1 1 
ATOM   8409  N N   . ILE B 1 431 ? 115.885 104.616 154.699 1.00 51.71  ?  420 ILE B N   1 
ATOM   8410  C CA  . ILE B 1 431 ? 116.842 103.778 155.419 1.00 51.71  ?  420 ILE B CA  1 
ATOM   8411  C C   . ILE B 1 431 ? 117.453 104.546 156.583 1.00 51.71  ?  420 ILE B C   1 
ATOM   8412  O O   . ILE B 1 431 ? 117.629 104.006 157.683 1.00 51.71  ?  420 ILE B O   1 
ATOM   8413  C CB  . ILE B 1 431 ? 117.923 103.252 154.458 1.00 51.71  ?  420 ILE B CB  1 
ATOM   8414  C CG1 . ILE B 1 431 ? 117.302 102.356 153.387 1.00 51.71  ?  420 ILE B CG1 1 
ATOM   8415  C CG2 . ILE B 1 431 ? 119.003 102.513 155.223 1.00 51.71  ?  420 ILE B CG2 1 
ATOM   8416  C CD1 . ILE B 1 431 ? 117.214 100.909 153.775 1.00 51.71  ?  420 ILE B CD1 1 
ATOM   8417  N N   . VAL B 1 432 ? 117.786 105.819 156.361 1.00 49.99  ?  421 VAL B N   1 
ATOM   8418  C CA  . VAL B 1 432 ? 118.330 106.644 157.438 1.00 49.99  ?  421 VAL B CA  1 
ATOM   8419  C C   . VAL B 1 432 ? 117.308 106.809 158.554 1.00 49.99  ?  421 VAL B C   1 
ATOM   8420  O O   . VAL B 1 432 ? 117.655 106.806 159.738 1.00 49.99  ?  421 VAL B O   1 
ATOM   8421  C CB  . VAL B 1 432 ? 118.791 108.002 156.886 1.00 49.99  ?  421 VAL B CB  1 
ATOM   8422  C CG1 . VAL B 1 432 ? 119.204 108.916 158.011 1.00 49.99  ?  421 VAL B CG1 1 
ATOM   8423  C CG2 . VAL B 1 432 ? 119.934 107.810 155.919 1.00 49.99  ?  421 VAL B CG2 1 
ATOM   8424  N N   . LEU B 1 433 ? 116.026 106.930 158.179 1.00 51.79  ?  422 LEU B N   1 
ATOM   8425  C CA  . LEU B 1 433 ? 114.980 107.012 159.185 1.00 51.79  ?  422 LEU B CA  1 
ATOM   8426  C C   . LEU B 1 433 ? 114.942 105.746 160.001 1.00 51.79  ?  422 LEU B C   1 
ATOM   8427  O O   . LEU B 1 433 ? 114.884 105.781 161.223 1.00 51.79  ?  422 LEU B O   1 
ATOM   8428  C CB  . LEU B 1 433 ? 113.619 107.207 158.535 1.00 51.79  ?  422 LEU B CB  1 
ATOM   8429  C CG  . LEU B 1 433 ? 112.410 107.176 159.465 1.00 51.79  ?  422 LEU B CG  1 
ATOM   8430  C CD1 . LEU B 1 433 ? 112.300 108.497 160.201 1.00 51.79  ?  422 LEU B CD1 1 
ATOM   8431  C CD2 . LEU B 1 433 ? 111.146 106.914 158.666 1.00 51.79  ?  422 LEU B CD2 1 
ATOM   8432  N N   . ILE B 1 434 ? 114.974 104.622 159.324 1.00 53.40  ?  423 ILE B N   1 
ATOM   8433  C CA  . ILE B 1 434 ? 114.907 103.337 160.016 1.00 53.40  ?  423 ILE B CA  1 
ATOM   8434  C C   . ILE B 1 434 ? 116.062 103.209 160.998 1.00 53.40  ?  423 ILE B C   1 
ATOM   8435  O O   . ILE B 1 434 ? 115.903 102.698 162.111 1.00 53.40  ?  423 ILE B O   1 
ATOM   8436  C CB  . ILE B 1 434 ? 114.900 102.181 158.999 1.00 53.40  ?  423 ILE B CB  1 
ATOM   8437  C CG1 . ILE B 1 434 ? 113.545 102.086 158.302 1.00 53.40  ?  423 ILE B CG1 1 
ATOM   8438  C CG2 . ILE B 1 434 ? 115.231 100.865 159.674 1.00 53.40  ?  423 ILE B CG2 1 
ATOM   8439  C CD1 . ILE B 1 434 ? 113.499 101.039 157.219 1.00 53.40  ?  423 ILE B CD1 1 
ATOM   8440  N N   . VAL B 1 435 ? 117.244 103.677 160.597 1.00 53.17  ?  424 VAL B N   1 
ATOM   8441  C CA  . VAL B 1 435 ? 118.402 103.615 161.487 1.00 53.17  ?  424 VAL B CA  1 
ATOM   8442  C C   . VAL B 1 435 ? 118.222 104.564 162.666 1.00 53.17  ?  424 VAL B C   1 
ATOM   8443  O O   . VAL B 1 435 ? 118.569 104.236 163.806 1.00 53.17  ?  424 VAL B O   1 
ATOM   8444  C CB  . VAL B 1 435 ? 119.694 103.912 160.705 1.00 53.17  ?  424 VAL B CB  1 
ATOM   8445  C CG1 . VAL B 1 435 ? 120.847 104.162 161.648 1.00 53.17  ?  424 VAL B CG1 1 
ATOM   8446  C CG2 . VAL B 1 435 ? 120.019 102.759 159.780 1.00 53.17  ?  424 VAL B CG2 1 
ATOM   8447  N N   . VAL B 1 436 ? 117.630 105.729 162.459 1.00 53.16  ?  425 VAL B N   1 
ATOM   8448  C CA  . VAL B 1 436 ? 117.449 106.712 163.541 1.00 53.16  ?  425 VAL B CA  1 
ATOM   8449  C C   . VAL B 1 436 ? 116.426 106.325 164.617 1.00 53.16  ?  425 VAL B C   1 
ATOM   8450  O O   . VAL B 1 436 ? 116.521 106.784 165.750 1.00 53.16  ?  425 VAL B O   1 
ATOM   8451  C CB  . VAL B 1 436 ? 117.055 108.094 162.967 1.00 53.16  ?  425 VAL B CB  1 
ATOM   8452  C CG1 . VAL B 1 436 ? 116.555 109.034 164.053 1.00 53.16  ?  425 VAL B CG1 1 
ATOM   8453  C CG2 . VAL B 1 436 ? 118.217 108.710 162.208 1.00 53.16  ?  425 VAL B CG2 1 
ATOM   8454  N N   . LEU B 1 437 ? 115.468 105.467 164.292 1.00 54.37  ?  426 LEU B N   1 
ATOM   8455  C CA  . LEU B 1 437 ? 114.404 105.152 165.250 1.00 54.37  ?  426 LEU B CA  1 
ATOM   8456  C C   . LEU B 1 437 ? 114.397 103.750 165.836 1.00 54.37  ?  426 LEU B C   1 
ATOM   8457  O O   . LEU B 1 437 ? 113.919 103.563 166.949 1.00 54.37  ?  426 LEU B O   1 
ATOM   8458  C CB  . LEU B 1 437 ? 113.043 105.383 164.585 1.00 54.37  ?  426 LEU B CB  1 
ATOM   8459  C CG  . LEU B 1 437 ? 112.757 106.788 164.056 1.00 54.37  ?  426 LEU B CG  1 
ATOM   8460  C CD1 . LEU B 1 437 ? 111.393 106.837 163.390 1.00 54.37  ?  426 LEU B CD1 1 
ATOM   8461  C CD2 . LEU B 1 437 ? 112.841 107.806 165.179 1.00 54.37  ?  426 LEU B CD2 1 
ATOM   8462  N N   . ALA B 1 438 ? 114.918 102.764 165.120 1.00 56.71  ?  427 ALA B N   1 
ATOM   8463  C CA  . ALA B 1 438 ? 114.811 101.387 165.602 1.00 56.71  ?  427 ALA B CA  1 
ATOM   8464  C C   . ALA B 1 438 ? 116.105 100.594 165.737 1.00 56.71  ?  427 ALA B C   1 
ATOM   8465  O O   . ALA B 1 438 ? 116.319 99.947  166.752 1.00 56.71  ?  427 ALA B O   1 
ATOM   8466  C CB  . ALA B 1 438 ? 113.856 100.622 164.696 1.00 56.71  ?  427 ALA B CB  1 
ATOM   8467  N N   . ILE B 1 439 ? 116.961 100.615 164.728 1.00 56.82  ?  428 ILE B N   1 
ATOM   8468  C CA  . ILE B 1 439 ? 118.152 99.764  164.762 1.00 56.82  ?  428 ILE B CA  1 
ATOM   8469  C C   . ILE B 1 439 ? 119.465 100.486 165.044 1.00 56.82  ?  428 ILE B C   1 
ATOM   8470  O O   . ILE B 1 439 ? 120.531 99.892  164.929 1.00 56.82  ?  428 ILE B O   1 
ATOM   8471  C CB  . ILE B 1 439 ? 118.285 98.992  163.437 1.00 56.82  ?  428 ILE B CB  1 
ATOM   8472  C CG1 . ILE B 1 439 ? 118.414 99.964  162.266 1.00 56.82  ?  428 ILE B CG1 1 
ATOM   8473  C CG2 . ILE B 1 439 ? 117.090 98.075  163.242 1.00 56.82  ?  428 ILE B CG2 1 
ATOM   8474  C CD1 . ILE B 1 439 ? 118.578 99.278  160.929 1.00 56.82  ?  428 ILE B CD1 1 
ATOM   8475  N N   . GLY B 1 440 ? 119.396 101.752 165.413 1.00 57.68  ?  429 GLY B N   1 
ATOM   8476  C CA  . GLY B 1 440 ? 120.599 102.509 165.697 1.00 57.68  ?  429 GLY B CA  1 
ATOM   8477  C C   . GLY B 1 440 ? 121.434 101.871 166.779 1.00 57.68  ?  429 GLY B C   1 
ATOM   8478  O O   . GLY B 1 440 ? 122.656 101.981 166.777 1.00 57.68  ?  429 GLY B O   1 
ATOM   8479  N N   . PHE B 1 441 ? 120.779 101.201 167.713 1.00 59.01  ?  430 PHE B N   1 
ATOM   8480  C CA  . PHE B 1 441 ? 121.500 100.520 168.780 1.00 59.01  ?  430 PHE B CA  1 
ATOM   8481  C C   . PHE B 1 441 ? 122.543 99.544  168.256 1.00 59.01  ?  430 PHE B C   1 
ATOM   8482  O O   . PHE B 1 441 ? 123.454 99.172  169.001 1.00 59.01  ?  430 PHE B O   1 
ATOM   8483  C CB  . PHE B 1 441 ? 120.514 99.782  169.685 1.00 59.01  ?  430 PHE B CB  1 
ATOM   8484  C CG  . PHE B 1 441 ? 119.869 98.593  169.031 1.00 59.01  ?  430 PHE B CG  1 
ATOM   8485  C CD1 . PHE B 1 441 ? 118.776 98.753  168.201 1.00 59.01  ?  430 PHE B CD1 1 
ATOM   8486  C CD2 . PHE B 1 441 ? 120.350 97.315  169.255 1.00 59.01  ?  430 PHE B CD2 1 
ATOM   8487  C CE1 . PHE B 1 441 ? 118.181 97.663  167.600 1.00 59.01  ?  430 PHE B CE1 1 
ATOM   8488  C CE2 . PHE B 1 441 ? 119.760 96.224  168.656 1.00 59.01  ?  430 PHE B CE2 1 
ATOM   8489  C CZ  . PHE B 1 441 ? 118.675 96.399  167.828 1.00 59.01  ?  430 PHE B CZ  1 
ATOM   8490  N N   . LEU B 1 442 ? 122.426 99.112  167.000 1.00 58.35  ?  431 LEU B N   1 
ATOM   8491  C CA  . LEU B 1 442 ? 123.419 98.204  166.441 1.00 58.35  ?  431 LEU B CA  1 
ATOM   8492  C C   . LEU B 1 442 ? 124.720 98.924  166.124 1.00 58.35  ?  431 LEU B C   1 
ATOM   8493  O O   . LEU B 1 442 ? 125.773 98.286  166.048 1.00 58.35  ?  431 LEU B O   1 
ATOM   8494  C CB  . LEU B 1 442 ? 122.873 97.532  165.185 1.00 58.35  ?  431 LEU B CB  1 
ATOM   8495  C CG  . LEU B 1 442 ? 121.643 96.649  165.352 1.00 58.35  ?  431 LEU B CG  1 
ATOM   8496  C CD1 . LEU B 1 442 ? 121.004 96.382  164.009 1.00 58.35  ?  431 LEU B CD1 1 
ATOM   8497  C CD2 . LEU B 1 442 ? 122.021 95.352  166.028 1.00 58.35  ?  431 LEU B CD2 1 
ATOM   8498  N N   . LEU B 1 443 ? 124.671 100.239 165.929 1.00 58.54  ?  432 LEU B N   1 
ATOM   8499  C CA  . LEU B 1 443 ? 125.868 101.012 165.642 1.00 58.54  ?  432 LEU B CA  1 
ATOM   8500  C C   . LEU B 1 443 ? 126.550 101.517 166.904 1.00 58.54  ?  432 LEU B C   1 
ATOM   8501  O O   . LEU B 1 443 ? 127.352 102.452 166.835 1.00 58.54  ?  432 LEU B O   1 
ATOM   8502  C CB  . LEU B 1 443 ? 125.528 102.179 164.716 1.00 58.54  ?  432 LEU B CB  1 
ATOM   8503  C CG  . LEU B 1 443 ? 125.155 101.764 163.294 1.00 58.54  ?  432 LEU B CG  1 
ATOM   8504  C CD1 . LEU B 1 443 ? 124.592 102.941 162.526 1.00 58.54  ?  432 LEU B CD1 1 
ATOM   8505  C CD2 . LEU B 1 443 ? 126.354 101.173 162.575 1.00 58.54  ?  432 LEU B CD2 1 
ATOM   8506  N N   . ALA B 1 444 ? 126.251 100.914 168.049 1.00 60.70  ?  433 ALA B N   1 
ATOM   8507  C CA  . ALA B 1 444 ? 126.838 101.294 169.325 1.00 60.70  ?  433 ALA B CA  1 
ATOM   8508  C C   . ALA B 1 444 ? 128.261 100.763 169.492 1.00 60.70  ?  433 ALA B C   1 
ATOM   8509  O O   . ALA B 1 444 ? 129.143 101.529 169.896 1.00 60.70  ?  433 ALA B O   1 
ATOM   8510  C CB  . ALA B 1 444 ? 125.950 100.824 170.479 1.00 60.70  ?  433 ALA B CB  1 
ATOM   8511  N N   . PRO B 1 445 ? 128.549 99.488  169.213 1.00 61.45  ?  434 PRO B N   1 
ATOM   8512  C CA  . PRO B 1 445 ? 129.914 98.985  169.396 1.00 61.45  ?  434 PRO B CA  1 
ATOM   8513  C C   . PRO B 1 445 ? 130.864 99.276  168.248 1.00 61.45  ?  434 PRO B C   1 
ATOM   8514  O O   . PRO B 1 445 ? 131.939 98.675  168.197 1.00 61.45  ?  434 PRO B O   1 
ATOM   8515  C CB  . PRO B 1 445 ? 129.690 97.475  169.539 1.00 61.45  ?  434 PRO B CB  1 
ATOM   8516  C CG  . PRO B 1 445 ? 128.568 97.219  168.648 1.00 61.45  ?  434 PRO B CG  1 
ATOM   8517  C CD  . PRO B 1 445 ? 127.644 98.389  168.822 1.00 61.45  ?  434 PRO B CD  1 
ATOM   8518  N N   . LEU B 1 446 ? 130.514 100.168 167.327 1.00 59.56  ?  435 LEU B N   1 
ATOM   8519  C CA  . LEU B 1 446 ? 131.367 100.448 166.183 1.00 59.56  ?  435 LEU B CA  1 
ATOM   8520  C C   . LEU B 1 446 ? 132.382 101.528 166.526 1.00 59.56  ?  435 LEU B C   1 
ATOM   8521  O O   . LEU B 1 446 ? 132.036 102.565 167.093 1.00 59.56  ?  435 LEU B O   1 
ATOM   8522  C CB  . LEU B 1 446 ? 130.522 100.883 164.987 1.00 59.56  ?  435 LEU B CB  1 
ATOM   8523  C CG  . LEU B 1 446 ? 131.254 101.194 163.681 1.00 59.56  ?  435 LEU B CG  1 
ATOM   8524  C CD1 . LEU B 1 446 ? 131.576 99.921  162.929 1.00 59.56  ?  435 LEU B CD1 1 
ATOM   8525  C CD2 . LEU B 1 446 ? 130.418 102.120 162.830 1.00 59.56  ?  435 LEU B CD2 1 
ATOM   8526  N N   . GLN B 1 447 ? 133.640 101.278 166.175 1.00 60.37  ?  436 GLN B N   1 
ATOM   8527  C CA  . GLN B 1 447 ? 134.718 102.191 166.513 1.00 60.37  ?  436 GLN B CA  1 
ATOM   8528  C C   . GLN B 1 447 ? 134.707 103.413 165.603 1.00 60.37  ?  436 GLN B C   1 
ATOM   8529  O O   . GLN B 1 447 ? 134.264 103.365 164.455 1.00 60.37  ?  436 GLN B O   1 
ATOM   8530  C CB  . GLN B 1 447 ? 136.071 101.492 166.407 1.00 60.37  ?  436 GLN B CB  1 
ATOM   8531  C CG  . GLN B 1 447 ? 136.120 100.112 167.024 1.00 60.37  ?  436 GLN B CG  1 
ATOM   8532  C CD  . GLN B 1 447 ? 137.485 99.476  166.888 1.00 60.37  ?  436 GLN B CD  1 
ATOM   8533  O OE1 . GLN B 1 447 ? 138.488 100.041 167.313 1.00 60.37  ?  436 GLN B OE1 1 
ATOM   8534  N NE2 . GLN B 1 447 ? 137.531 98.296  166.288 1.00 60.37  ?  436 GLN B NE2 1 
ATOM   8535  N N   . LYS B 1 448 ? 135.212 104.524 166.133 1.00 56.39  ?  437 LYS B N   1 
ATOM   8536  C CA  . LYS B 1 448 ? 135.346 105.729 165.330 1.00 56.39  ?  437 LYS B CA  1 
ATOM   8537  C C   . LYS B 1 448 ? 136.525 105.652 164.374 1.00 56.39  ?  437 LYS B C   1 
ATOM   8538  O O   . LYS B 1 448 ? 136.560 106.395 163.388 1.00 56.39  ?  437 LYS B O   1 
ATOM   8539  C CB  . LYS B 1 448 ? 135.489 106.948 166.234 1.00 56.39  ?  437 LYS B CB  1 
ATOM   8540  C CG  . LYS B 1 448 ? 134.430 107.042 167.303 1.00 56.39  ?  437 LYS B CG  1 
ATOM   8541  C CD  . LYS B 1 448 ? 134.571 108.323 168.088 1.00 56.39  ?  437 LYS B CD  1 
ATOM   8542  C CE  . LYS B 1 448 ? 133.448 108.477 169.084 1.00 56.39  ?  437 LYS B CE  1 
ATOM   8543  N NZ  . LYS B 1 448 ? 133.560 109.763 169.814 1.00 56.39  1  437 LYS B NZ  1 
ATOM   8544  N N   . SER B 1 449 ? 137.483 104.762 164.640 1.00 57.44  ?  438 SER B N   1 
ATOM   8545  C CA  . SER B 1 449 ? 138.579 104.563 163.702 1.00 57.44  ?  438 SER B CA  1 
ATOM   8546  C C   . SER B 1 449 ? 138.089 103.916 162.418 1.00 57.44  ?  438 SER B C   1 
ATOM   8547  O O   . SER B 1 449 ? 138.646 104.161 161.348 1.00 57.44  ?  438 SER B O   1 
ATOM   8548  C CB  . SER B 1 449 ? 139.678 103.723 164.345 1.00 57.44  ?  438 SER B CB  1 
ATOM   8549  O OG  . SER B 1 449 ? 139.157 102.523 164.878 1.00 57.44  ?  438 SER B OG  1 
ATOM   8550  N N   . VAL B 1 450 ? 137.025 103.114 162.492 1.00 56.78  ?  439 VAL B N   1 
ATOM   8551  C CA  . VAL B 1 450 ? 136.465 102.517 161.282 1.00 56.78  ?  439 VAL B CA  1 
ATOM   8552  C C   . VAL B 1 450 ? 135.780 103.577 160.430 1.00 56.78  ?  439 VAL B C   1 
ATOM   8553  O O   . VAL B 1 450 ? 135.930 103.605 159.202 1.00 56.78  ?  439 VAL B O   1 
ATOM   8554  C CB  . VAL B 1 450 ? 135.506 101.373 161.652 1.00 56.78  ?  439 VAL B CB  1 
ATOM   8555  C CG1 . VAL B 1 450 ? 134.823 100.837 160.414 1.00 56.78  ?  439 VAL B CG1 1 
ATOM   8556  C CG2 . VAL B 1 450 ? 136.264 100.272 162.354 1.00 56.78  ?  439 VAL B CG2 1 
ATOM   8557  N N   . LEU B 1 451 ? 135.020 104.470 161.068 1.00 53.87  ?  440 LEU B N   1 
ATOM   8558  C CA  . LEU B 1 451 ? 134.422 105.586 160.343 1.00 53.87  ?  440 LEU B CA  1 
ATOM   8559  C C   . LEU B 1 451 ? 135.495 106.468 159.719 1.00 53.87  ?  440 LEU B C   1 
ATOM   8560  O O   . LEU B 1 451 ? 135.366 106.896 158.564 1.00 53.87  ?  440 LEU B O   1 
ATOM   8561  C CB  . LEU B 1 451 ? 133.538 106.401 161.282 1.00 53.87  ?  440 LEU B CB  1 
ATOM   8562  C CG  . LEU B 1 451 ? 132.396 105.666 161.981 1.00 53.87  ?  440 LEU B CG  1 
ATOM   8563  C CD1 . LEU B 1 451 ? 131.663 106.598 162.925 1.00 53.87  ?  440 LEU B CD1 1 
ATOM   8564  C CD2 . LEU B 1 451 ? 131.445 105.082 160.958 1.00 53.87  ?  440 LEU B CD2 1 
ATOM   8565  N N   . ALA B 1 452 ? 136.565 106.738 160.467 1.00 55.73  ?  441 ALA B N   1 
ATOM   8566  C CA  . ALA B 1 452 ? 137.662 107.532 159.927 1.00 55.73  ?  441 ALA B CA  1 
ATOM   8567  C C   . ALA B 1 452 ? 138.350 106.817 158.769 1.00 55.73  ?  441 ALA B C   1 
ATOM   8568  O O   . ALA B 1 452 ? 138.754 107.453 157.794 1.00 55.73  ?  441 ALA B O   1 
ATOM   8569  C CB  . ALA B 1 452 ? 138.661 107.854 161.033 1.00 55.73  ?  441 ALA B CB  1 
ATOM   8570  N N   . ALA B 1 453 ? 138.478 105.494 158.851 1.00 56.55  ?  442 ALA B N   1 
ATOM   8571  C CA  . ALA B 1 453 ? 139.110 104.739 157.776 1.00 56.55  ?  442 ALA B CA  1 
ATOM   8572  C C   . ALA B 1 453 ? 138.268 104.770 156.509 1.00 56.55  ?  442 ALA B C   1 
ATOM   8573  O O   . ALA B 1 453 ? 138.808 104.854 155.404 1.00 56.55  ?  442 ALA B O   1 
ATOM   8574  C CB  . ALA B 1 453 ? 139.359 103.303 158.221 1.00 56.55  ?  442 ALA B CB  1 
ATOM   8575  N N   . LEU B 1 454 ? 136.942 104.708 156.644 1.00 57.03  ?  443 LEU B N   1 
ATOM   8576  C CA  . LEU B 1 454 ? 136.090 104.860 155.467 1.00 57.03  ?  443 LEU B CA  1 
ATOM   8577  C C   . LEU B 1 454 ? 136.224 106.256 154.866 1.00 57.03  ?  443 LEU B C   1 
ATOM   8578  O O   . LEU B 1 454 ? 136.405 106.410 153.645 1.00 57.03  ?  443 LEU B O   1 
ATOM   8579  C CB  . LEU B 1 454 ? 134.633 104.576 155.828 1.00 57.03  ?  443 LEU B CB  1 
ATOM   8580  C CG  . LEU B 1 454 ? 134.324 103.232 156.479 1.00 57.03  ?  443 LEU B CG  1 
ATOM   8581  C CD1 . LEU B 1 454 ? 132.848 103.142 156.790 1.00 57.03  ?  443 LEU B CD1 1 
ATOM   8582  C CD2 . LEU B 1 454 ? 134.749 102.095 155.586 1.00 57.03  ?  443 LEU B CD2 1 
ATOM   8583  N N   . ALA B 1 455 ? 136.145 107.286 155.711 1.00 55.91  ?  444 ALA B N   1 
ATOM   8584  C CA  . ALA B 1 455 ? 136.278 108.653 155.223 1.00 55.91  ?  444 ALA B CA  1 
ATOM   8585  C C   . ALA B 1 455 ? 137.629 108.873 154.553 1.00 55.91  ?  444 ALA B C   1 
ATOM   8586  O O   . ALA B 1 455 ? 137.746 109.682 153.629 1.00 55.91  ?  444 ALA B O   1 
ATOM   8587  C CB  . ALA B 1 455 ? 136.075 109.642 156.367 1.00 55.91  ?  444 ALA B CB  1 
ATOM   8588  N N   . LEU B 1 456 ? 138.661 108.154 155.003 1.00 56.30  ?  445 LEU B N   1 
ATOM   8589  C CA  . LEU B 1 456 ? 139.972 108.262 154.373 1.00 56.30  ?  445 LEU B CA  1 
ATOM   8590  C C   . LEU B 1 456 ? 140.016 107.494 153.062 1.00 56.30  ?  445 LEU B C   1 
ATOM   8591  O O   . LEU B 1 456 ? 140.668 107.925 152.105 1.00 56.30  ?  445 LEU B O   1 
ATOM   8592  C CB  . LEU B 1 456 ? 141.059 107.756 155.319 1.00 56.30  ?  445 LEU B CB  1 
ATOM   8593  C CG  . LEU B 1 456 ? 141.501 108.692 156.438 1.00 56.30  ?  445 LEU B CG  1 
ATOM   8594  C CD1 . LEU B 1 456 ? 142.627 108.061 157.222 1.00 56.30  ?  445 LEU B CD1 1 
ATOM   8595  C CD2 . LEU B 1 456 ? 141.926 110.021 155.866 1.00 56.30  ?  445 LEU B CD2 1 
ATOM   8596  N N   . GLY B 1 457 ? 139.349 106.344 153.003 1.00 58.55  ?  446 GLY B N   1 
ATOM   8597  C CA  . GLY B 1 457 ? 139.259 105.606 151.760 1.00 58.55  ?  446 GLY B CA  1 
ATOM   8598  C C   . GLY B 1 457 ? 138.585 106.378 150.655 1.00 58.55  ?  446 GLY B C   1 
ATOM   8599  O O   . GLY B 1 457 ? 138.910 106.172 149.482 1.00 58.55  ?  446 GLY B O   1 
ATOM   8600  N N   . ASN B 1 458 ? 137.662 107.272 150.996 1.00 59.37  ?  447 ASN B N   1 
ATOM   8601  C CA  . ASN B 1 458 ? 136.991 108.087 149.991 1.00 59.37  ?  447 ASN B CA  1 
ATOM   8602  C C   . ASN B 1 458 ? 137.814 109.287 149.532 1.00 59.37  ?  447 ASN B C   1 
ATOM   8603  O O   . ASN B 1 458 ? 137.252 110.212 148.940 1.00 59.37  ?  447 ASN B O   1 
ATOM   8604  C CB  . ASN B 1 458 ? 135.639 108.569 150.519 1.00 59.37  ?  447 ASN B CB  1 
ATOM   8605  C CG  . ASN B 1 458 ? 134.551 107.537 150.346 1.00 59.37  ?  447 ASN B CG  1 
ATOM   8606  O OD1 . ASN B 1 458 ? 133.912 107.126 151.313 1.00 59.37  ?  447 ASN B OD1 1 
ATOM   8607  N ND2 . ASN B 1 458 ? 134.327 107.116 149.110 1.00 59.37  ?  447 ASN B ND2 1 
ATOM   8608  N N   . LEU B 1 459 ? 139.122 109.294 149.775 1.00 55.74  ?  448 LEU B N   1 
ATOM   8609  C CA  . LEU B 1 459 ? 139.975 110.437 149.473 1.00 55.74  ?  448 LEU B CA  1 
ATOM   8610  C C   . LEU B 1 459 ? 140.912 110.211 148.296 1.00 55.74  ?  448 LEU B C   1 
ATOM   8611  O O   . LEU B 1 459 ? 141.628 111.141 147.918 1.00 55.74  ?  448 LEU B O   1 
ATOM   8612  C CB  . LEU B 1 459 ? 140.807 110.811 150.703 1.00 55.74  ?  448 LEU B CB  1 
ATOM   8613  C CG  . LEU B 1 459 ? 140.471 112.084 151.475 1.00 55.74  ?  448 LEU B CG  1 
ATOM   8614  C CD1 . LEU B 1 459 ? 139.067 112.054 152.023 1.00 55.74  ?  448 LEU B CD1 1 
ATOM   8615  C CD2 . LEU B 1 459 ? 141.465 112.228 152.601 1.00 55.74  ?  448 LEU B CD2 1 
ATOM   8616  N N   . LYS B 1 460 ? 140.937 109.011 147.715 1.00 59.07  ?  449 LYS B N   1 
ATOM   8617  C CA  . LYS B 1 460 ? 141.897 108.723 146.653 1.00 59.07  ?  449 LYS B CA  1 
ATOM   8618  C C   . LYS B 1 460 ? 141.666 109.612 145.437 1.00 59.07  ?  449 LYS B C   1 
ATOM   8619  O O   . LYS B 1 460 ? 142.617 110.134 144.845 1.00 59.07  ?  449 LYS B O   1 
ATOM   8620  C CB  . LYS B 1 460 ? 141.818 107.248 146.262 1.00 59.07  ?  449 LYS B CB  1 
ATOM   8621  C CG  . LYS B 1 460 ? 142.616 106.894 145.021 1.00 59.07  ?  449 LYS B CG  1 
ATOM   8622  C CD  . LYS B 1 460 ? 142.612 105.398 144.774 1.00 59.07  ?  449 LYS B CD  1 
ATOM   8623  C CE  . LYS B 1 460 ? 141.964 105.063 143.445 1.00 59.07  ?  449 LYS B CE  1 
ATOM   8624  N NZ  . LYS B 1 460 ? 142.208 106.122 142.432 1.00 59.07  1  449 LYS B NZ  1 
ATOM   8625  N N   . GLY B 1 461 ? 140.403 109.796 145.053 1.00 56.85  ?  450 GLY B N   1 
ATOM   8626  C CA  . GLY B 1 461 ? 140.106 110.577 143.863 1.00 56.85  ?  450 GLY B CA  1 
ATOM   8627  C C   . GLY B 1 461 ? 140.577 112.012 143.972 1.00 56.85  ?  450 GLY B C   1 
ATOM   8628  O O   . GLY B 1 461 ? 141.134 112.569 143.025 1.00 56.85  ?  450 GLY B O   1 
ATOM   8629  N N   . MET B 1 462 ? 140.363 112.631 145.135 1.00 55.02  ?  451 MET B N   1 
ATOM   8630  C CA  . MET B 1 462 ? 140.791 114.010 145.323 1.00 55.02  ?  451 MET B CA  1 
ATOM   8631  C C   . MET B 1 462 ? 142.290 114.109 145.572 1.00 55.02  ?  451 MET B C   1 
ATOM   8632  O O   . MET B 1 462 ? 142.917 115.090 145.165 1.00 55.02  ?  451 MET B O   1 
ATOM   8633  C CB  . MET B 1 462 ? 140.022 114.646 146.477 1.00 55.02  ?  451 MET B CB  1 
ATOM   8634  C CG  . MET B 1 462 ? 138.557 114.886 146.178 1.00 55.02  ?  451 MET B CG  1 
ATOM   8635  S SD  . MET B 1 462 ? 137.775 115.993 147.360 1.00 55.02  ?  451 MET B SD  1 
ATOM   8636  C CE  . MET B 1 462 ? 137.847 115.007 148.851 1.00 55.02  ?  451 MET B CE  1 
ATOM   8637  N N   . LEU B 1 463 ? 142.881 113.111 146.230 1.00 53.51  ?  452 LEU B N   1 
ATOM   8638  C CA  . LEU B 1 463 ? 144.306 113.175 146.528 1.00 53.51  ?  452 LEU B CA  1 
ATOM   8639  C C   . LEU B 1 463 ? 145.156 112.951 145.289 1.00 53.51  ?  452 LEU B C   1 
ATOM   8640  O O   . LEU B 1 463 ? 146.258 113.497 145.194 1.00 53.51  ?  452 LEU B O   1 
ATOM   8641  C CB  . LEU B 1 463 ? 144.672 112.156 147.606 1.00 53.51  ?  452 LEU B CB  1 
ATOM   8642  C CG  . LEU B 1 463 ? 144.560 112.649 149.045 1.00 53.51  ?  452 LEU B CG  1 
ATOM   8643  C CD1 . LEU B 1 463 ? 145.056 111.593 150.005 1.00 53.51  ?  452 LEU B CD1 1 
ATOM   8644  C CD2 . LEU B 1 463 ? 145.334 113.940 149.220 1.00 53.51  ?  452 LEU B CD2 1 
ATOM   8645  N N   . MET B 1 464 ? 144.678 112.155 144.335 1.00 57.72  ?  453 MET B N   1 
ATOM   8646  C CA  . MET B 1 464 ? 145.481 111.947 143.137 1.00 57.72  ?  453 MET B CA  1 
ATOM   8647  C C   . MET B 1 464 ? 145.357 113.084 142.134 1.00 57.72  ?  453 MET B C   1 
ATOM   8648  O O   . MET B 1 464 ? 145.861 112.948 141.015 1.00 57.72  ?  453 MET B O   1 
ATOM   8649  C CB  . MET B 1 464 ? 145.114 110.620 142.477 1.00 57.72  ?  453 MET B CB  1 
ATOM   8650  C CG  . MET B 1 464 ? 143.766 110.601 141.793 1.00 57.72  ?  453 MET B CG  1 
ATOM   8651  S SD  . MET B 1 464 ? 143.243 108.920 141.409 1.00 57.72  ?  453 MET B SD  1 
ATOM   8652  C CE  . MET B 1 464 ? 144.804 108.048 141.502 1.00 57.72  ?  453 MET B CE  1 
ATOM   8653  N N   . GLN B 1 465 ? 144.715 114.192 142.498 1.00 50.62  ?  454 GLN B N   1 
ATOM   8654  C CA  . GLN B 1 465 ? 144.703 115.392 141.671 1.00 50.62  ?  454 GLN B CA  1 
ATOM   8655  C C   . GLN B 1 465 ? 146.001 116.174 141.756 1.00 50.62  ?  454 GLN B C   1 
ATOM   8656  O O   . GLN B 1 465 ? 146.085 117.263 141.187 1.00 50.62  ?  454 GLN B O   1 
ATOM   8657  C CB  . GLN B 1 465 ? 143.539 116.303 142.058 1.00 50.62  ?  454 GLN B CB  1 
ATOM   8658  C CG  . GLN B 1 465 ? 142.168 115.726 141.814 1.00 50.62  ?  454 GLN B CG  1 
ATOM   8659  C CD  . GLN B 1 465 ? 141.072 116.658 142.280 1.00 50.62  ?  454 GLN B CD  1 
ATOM   8660  O OE1 . GLN B 1 465 ? 140.012 116.743 141.670 1.00 50.62  ?  454 GLN B OE1 1 
ATOM   8661  N NE2 . GLN B 1 465 ? 141.322 117.359 143.372 1.00 50.62  ?  454 GLN B NE2 1 
ATOM   8662  N N   . PHE B 1 466 ? 147.004 115.658 142.468 1.00 49.94  ?  455 PHE B N   1 
ATOM   8663  C CA  . PHE B 1 466 ? 148.322 116.275 142.450 1.00 49.94  ?  455 PHE B CA  1 
ATOM   8664  C C   . PHE B 1 466 ? 148.994 116.129 141.097 1.00 49.94  ?  455 PHE B C   1 
ATOM   8665  O O   . PHE B 1 466 ? 149.941 116.864 140.803 1.00 49.94  ?  455 PHE B O   1 
ATOM   8666  C CB  . PHE B 1 466 ? 149.203 115.663 143.537 1.00 49.94  ?  455 PHE B CB  1 
ATOM   8667  C CG  . PHE B 1 466 ? 149.054 116.316 144.875 1.00 49.94  ?  455 PHE B CG  1 
ATOM   8668  C CD1 . PHE B 1 466 ? 149.610 117.556 145.121 1.00 49.94  ?  455 PHE B CD1 1 
ATOM   8669  C CD2 . PHE B 1 466 ? 148.355 115.692 145.887 1.00 49.94  ?  455 PHE B CD2 1 
ATOM   8670  C CE1 . PHE B 1 466 ? 149.471 118.154 146.348 1.00 49.94  ?  455 PHE B CE1 1 
ATOM   8671  C CE2 . PHE B 1 466 ? 148.220 116.287 147.117 1.00 49.94  ?  455 PHE B CE2 1 
ATOM   8672  C CZ  . PHE B 1 466 ? 148.778 117.518 147.347 1.00 49.94  ?  455 PHE B CZ  1 
ATOM   8673  N N   . ALA B 1 467 ? 148.523 115.198 140.268 1.00 51.99  ?  456 ALA B N   1 
ATOM   8674  C CA  . ALA B 1 467 ? 149.045 115.028 138.923 1.00 51.99  ?  456 ALA B CA  1 
ATOM   8675  C C   . ALA B 1 467 ? 148.667 116.172 137.997 1.00 51.99  ?  456 ALA B C   1 
ATOM   8676  O O   . ALA B 1 467 ? 149.215 116.259 136.895 1.00 51.99  ?  456 ALA B O   1 
ATOM   8677  C CB  . ALA B 1 467 ? 148.550 113.707 138.338 1.00 51.99  ?  456 ALA B CB  1 
ATOM   8678  N N   . GLU B 1 468 ? 147.745 117.042 138.411 1.00 53.74  ?  457 GLU B N   1 
ATOM   8679  C CA  . GLU B 1 468 ? 147.358 118.168 137.574 1.00 53.74  ?  457 GLU B CA  1 
ATOM   8680  C C   . GLU B 1 468 ? 148.428 119.243 137.528 1.00 53.74  ?  457 GLU B C   1 
ATOM   8681  O O   . GLU B 1 468 ? 148.420 120.064 136.611 1.00 53.74  ?  457 GLU B O   1 
ATOM   8682  C CB  . GLU B 1 468 ? 146.043 118.768 138.068 1.00 53.74  ?  457 GLU B CB  1 
ATOM   8683  C CG  . GLU B 1 468 ? 144.815 118.221 137.369 1.00 53.74  ?  457 GLU B CG  1 
ATOM   8684  C CD  . GLU B 1 468 ? 144.446 119.009 136.127 1.00 53.74  ?  457 GLU B CD  1 
ATOM   8685  O OE1 . GLU B 1 468 ? 144.009 120.171 136.267 1.00 53.74  ?  457 GLU B OE1 1 
ATOM   8686  O OE2 . GLU B 1 468 ? 144.591 118.470 135.012 1.00 53.74  -1 457 GLU B OE2 1 
ATOM   8687  N N   . ILE B 1 469 ? 149.355 119.250 138.485 1.00 51.03  ?  458 ILE B N   1 
ATOM   8688  C CA  . ILE B 1 469 ? 150.406 120.265 138.496 1.00 51.03  ?  458 ILE B CA  1 
ATOM   8689  C C   . ILE B 1 469 ? 151.271 120.153 137.246 1.00 51.03  ?  458 ILE B C   1 
ATOM   8690  O O   . ILE B 1 469 ? 151.498 121.139 136.539 1.00 51.03  ?  458 ILE B O   1 
ATOM   8691  C CB  . ILE B 1 469 ? 151.249 120.151 139.776 1.00 51.03  ?  458 ILE B CB  1 
ATOM   8692  C CG1 . ILE B 1 469 ? 150.357 120.256 141.007 1.00 51.03  ?  458 ILE B CG1 1 
ATOM   8693  C CG2 . ILE B 1 469 ? 152.317 121.225 139.804 1.00 51.03  ?  458 ILE B CG2 1 
ATOM   8694  C CD1 . ILE B 1 469 ? 151.086 120.008 142.291 1.00 51.03  ?  458 ILE B CD1 1 
ATOM   8695  N N   . GLY B 1 470 ? 151.759 118.948 136.948 1.00 52.49  ?  459 GLY B N   1 
ATOM   8696  C CA  . GLY B 1 470 ? 152.597 118.775 135.772 1.00 52.49  ?  459 GLY B CA  1 
ATOM   8697  C C   . GLY B 1 470 ? 151.842 119.001 134.476 1.00 52.49  ?  459 GLY B C   1 
ATOM   8698  O O   . GLY B 1 470 ? 152.367 119.612 133.539 1.00 52.49  ?  459 GLY B O   1 
ATOM   8699  N N   . ARG B 1 471 ? 150.599 118.521 134.406 1.00 52.96  ?  460 ARG B N   1 
ATOM   8700  C CA  . ARG B 1 471 ? 149.788 118.732 133.213 1.00 52.96  ?  460 ARG B CA  1 
ATOM   8701  C C   . ARG B 1 471 ? 149.568 120.213 132.951 1.00 52.96  ?  460 ARG B C   1 
ATOM   8702  O O   . ARG B 1 471 ? 149.772 120.689 131.828 1.00 52.96  ?  460 ARG B O   1 
ATOM   8703  C CB  . ARG B 1 471 ? 148.450 118.014 133.355 1.00 52.96  ?  460 ARG B CB  1 
ATOM   8704  C CG  . ARG B 1 471 ? 148.572 116.517 133.534 1.00 52.96  ?  460 ARG B CG  1 
ATOM   8705  C CD  . ARG B 1 471 ? 147.281 115.814 133.168 1.00 52.96  ?  460 ARG B CD  1 
ATOM   8706  N NE  . ARG B 1 471 ? 146.392 115.665 134.315 1.00 52.96  ?  460 ARG B NE  1 
ATOM   8707  C CZ  . ARG B 1 471 ? 146.238 114.536 134.995 1.00 52.96  ?  460 ARG B CZ  1 
ATOM   8708  N NH1 . ARG B 1 471 ? 145.407 114.488 136.025 1.00 52.96  1  460 ARG B NH1 1 
ATOM   8709  N NH2 . ARG B 1 471 ? 146.916 113.453 134.644 1.00 52.96  ?  460 ARG B NH2 1 
ATOM   8710  N N   . LEU B 1 472 ? 149.154 120.963 133.973 1.00 49.40  ?  461 LEU B N   1 
ATOM   8711  C CA  . LEU B 1 472 ? 148.919 122.386 133.799 1.00 49.40  ?  461 LEU B CA  1 
ATOM   8712  C C   . LEU B 1 472 ? 150.216 123.134 133.533 1.00 49.40  ?  461 LEU B C   1 
ATOM   8713  O O   . LEU B 1 472 ? 150.215 124.147 132.832 1.00 49.40  ?  461 LEU B O   1 
ATOM   8714  C CB  . LEU B 1 472 ? 148.207 122.946 135.028 1.00 49.40  ?  461 LEU B CB  1 
ATOM   8715  C CG  . LEU B 1 472 ? 146.776 122.445 135.194 1.00 49.40  ?  461 LEU B CG  1 
ATOM   8716  C CD1 . LEU B 1 472 ? 146.182 122.910 136.501 1.00 49.40  ?  461 LEU B CD1 1 
ATOM   8717  C CD2 . LEU B 1 472 ? 145.936 122.908 134.031 1.00 49.40  ?  461 LEU B CD2 1 
ATOM   8718  N N   . TRP B 1 473 ? 151.334 122.654 134.081 1.00 50.27  ?  462 TRP B N   1 
ATOM   8719  C CA  . TRP B 1 473 ? 152.622 123.240 133.734 1.00 50.27  ?  462 TRP B CA  1 
ATOM   8720  C C   . TRP B 1 473 ? 152.892 123.102 132.246 1.00 50.27  ?  462 TRP B C   1 
ATOM   8721  O O   . TRP B 1 473 ? 153.325 124.057 131.590 1.00 50.27  ?  462 TRP B O   1 
ATOM   8722  C CB  . TRP B 1 473 ? 153.737 122.578 134.537 1.00 50.27  ?  462 TRP B CB  1 
ATOM   8723  C CG  . TRP B 1 473 ? 155.082 123.147 134.243 1.00 50.27  ?  462 TRP B CG  1 
ATOM   8724  C CD1 . TRP B 1 473 ? 156.002 122.662 133.363 1.00 50.27  ?  462 TRP B CD1 1 
ATOM   8725  C CD2 . TRP B 1 473 ? 155.661 124.317 134.824 1.00 50.27  ?  462 TRP B CD2 1 
ATOM   8726  N NE1 . TRP B 1 473 ? 157.119 123.457 133.362 1.00 50.27  ?  462 TRP B NE1 1 
ATOM   8727  C CE2 . TRP B 1 473 ? 156.933 124.482 134.252 1.00 50.27  ?  462 TRP B CE2 1 
ATOM   8728  C CE3 . TRP B 1 473 ? 155.224 125.243 135.775 1.00 50.27  ?  462 TRP B CE3 1 
ATOM   8729  C CZ2 . TRP B 1 473 ? 157.772 125.530 134.598 1.00 50.27  ?  462 TRP B CZ2 1 
ATOM   8730  C CZ3 . TRP B 1 473 ? 156.058 126.281 136.116 1.00 50.27  ?  462 TRP B CZ3 1 
ATOM   8731  C CH2 . TRP B 1 473 ? 157.317 126.418 135.530 1.00 50.27  ?  462 TRP B CH2 1 
ATOM   8732  N N   . ARG B 1 474 ? 152.636 121.917 131.693 1.00 54.11  ?  463 ARG B N   1 
ATOM   8733  C CA  . ARG B 1 474 ? 152.819 121.718 130.261 1.00 54.11  ?  463 ARG B CA  1 
ATOM   8734  C C   . ARG B 1 474 ? 151.878 122.600 129.449 1.00 54.11  ?  463 ARG B C   1 
ATOM   8735  O O   . ARG B 1 474 ? 152.305 123.253 128.491 1.00 54.11  ?  463 ARG B O   1 
ATOM   8736  C CB  . ARG B 1 474 ? 152.607 120.249 129.909 1.00 54.11  ?  463 ARG B CB  1 
ATOM   8737  C CG  . ARG B 1 474 ? 153.822 119.376 130.135 1.00 54.11  ?  463 ARG B CG  1 
ATOM   8738  C CD  . ARG B 1 474 ? 153.615 117.991 129.551 1.00 54.11  ?  463 ARG B CD  1 
ATOM   8739  N NE  . ARG B 1 474 ? 152.694 117.187 130.347 1.00 54.11  ?  463 ARG B NE  1 
ATOM   8740  C CZ  . ARG B 1 474 ? 153.035 116.538 131.455 1.00 54.11  ?  463 ARG B CZ  1 
ATOM   8741  N NH1 . ARG B 1 474 ? 152.132 115.828 132.116 1.00 54.11  1  463 ARG B NH1 1 
ATOM   8742  N NH2 . ARG B 1 474 ? 154.280 116.597 131.906 1.00 54.11  ?  463 ARG B NH2 1 
ATOM   8743  N N   . LYS B 1 475 ? 150.596 122.640 129.818 1.00 50.66  ?  464 LYS B N   1 
ATOM   8744  C CA  . LYS B 1 475 ? 149.597 123.301 128.981 1.00 50.66  ?  464 LYS B CA  1 
ATOM   8745  C C   . LYS B 1 475 ? 149.555 124.808 129.205 1.00 50.66  ?  464 LYS B C   1 
ATOM   8746  O O   . LYS B 1 475 ? 149.831 125.589 128.290 1.00 50.66  ?  464 LYS B O   1 
ATOM   8747  C CB  . LYS B 1 475 ? 148.218 122.696 129.240 1.00 50.66  ?  464 LYS B CB  1 
ATOM   8748  C CG  . LYS B 1 475 ? 148.142 121.213 128.992 1.00 50.66  ?  464 LYS B CG  1 
ATOM   8749  C CD  . LYS B 1 475 ? 146.775 120.680 129.346 1.00 50.66  ?  464 LYS B CD  1 
ATOM   8750  C CE  . LYS B 1 475 ? 146.665 119.212 129.003 1.00 50.66  ?  464 LYS B CE  1 
ATOM   8751  N NZ  . LYS B 1 475 ? 145.263 118.729 129.131 1.00 50.66  1  464 LYS B NZ  1 
ATOM   8752  N N   . ASP B 1 476 ? 149.200 125.239 130.413 1.00 47.45  ?  465 ASP B N   1 
ATOM   8753  C CA  . ASP B 1 476 ? 148.969 126.651 130.695 1.00 47.45  ?  465 ASP B CA  1 
ATOM   8754  C C   . ASP B 1 476 ? 149.493 126.981 132.080 1.00 47.45  ?  465 ASP B C   1 
ATOM   8755  O O   . ASP B 1 476 ? 148.962 126.485 133.076 1.00 47.45  ?  465 ASP B O   1 
ATOM   8756  C CB  . ASP B 1 476 ? 147.478 126.989 130.598 1.00 47.45  ?  465 ASP B CB  1 
ATOM   8757  C CG  . ASP B 1 476 ? 147.229 128.463 130.366 1.00 47.45  ?  465 ASP B CG  1 
ATOM   8758  O OD1 . ASP B 1 476 ? 148.201 129.203 130.123 1.00 47.45  ?  465 ASP B OD1 1 
ATOM   8759  O OD2 . ASP B 1 476 ? 146.059 128.884 130.424 1.00 47.45  -1 465 ASP B OD2 1 
ATOM   8760  N N   . LYS B 1 477 ? 150.511 127.837 132.147 1.00 45.17  ?  466 LYS B N   1 
ATOM   8761  C CA  . LYS B 1 477 ? 151.136 128.153 133.424 1.00 45.17  ?  466 LYS B CA  1 
ATOM   8762  C C   . LYS B 1 477 ? 150.332 129.139 134.257 1.00 45.17  ?  466 LYS B C   1 
ATOM   8763  O O   . LYS B 1 477 ? 150.573 129.242 135.463 1.00 45.17  ?  466 LYS B O   1 
ATOM   8764  C CB  . LYS B 1 477 ? 152.544 128.692 133.199 1.00 45.17  ?  466 LYS B CB  1 
ATOM   8765  C CG  . LYS B 1 477 ? 153.480 127.672 132.595 1.00 45.17  ?  466 LYS B CG  1 
ATOM   8766  C CD  . LYS B 1 477 ? 154.910 128.152 132.615 1.00 45.17  ?  466 LYS B CD  1 
ATOM   8767  C CE  . LYS B 1 477 ? 155.683 127.569 131.453 1.00 45.17  ?  466 LYS B CE  1 
ATOM   8768  N NZ  . LYS B 1 477 ? 155.147 126.244 131.052 1.00 45.17  1  466 LYS B NZ  1 
ATOM   8769  N N   . TYR B 1 478 ? 149.374 129.846 133.660 1.00 41.99  ?  467 TYR B N   1 
ATOM   8770  C CA  . TYR B 1 478 ? 148.462 130.654 134.462 1.00 41.99  ?  467 TYR B CA  1 
ATOM   8771  C C   . TYR B 1 478 ? 147.504 129.768 135.246 1.00 41.99  ?  467 TYR B C   1 
ATOM   8772  O O   . TYR B 1 478 ? 147.194 130.050 136.408 1.00 41.99  ?  467 TYR B O   1 
ATOM   8773  C CB  . TYR B 1 478 ? 147.696 131.628 133.575 1.00 41.99  ?  467 TYR B CB  1 
ATOM   8774  C CG  . TYR B 1 478 ? 148.567 132.680 132.939 1.00 41.99  ?  467 TYR B CG  1 
ATOM   8775  C CD1 . TYR B 1 478 ? 148.974 133.795 133.652 1.00 41.99  ?  467 TYR B CD1 1 
ATOM   8776  C CD2 . TYR B 1 478 ? 148.988 132.557 131.625 1.00 41.99  ?  467 TYR B CD2 1 
ATOM   8777  C CE1 . TYR B 1 478 ? 149.773 134.753 133.074 1.00 41.99  ?  467 TYR B CE1 1 
ATOM   8778  C CE2 . TYR B 1 478 ? 149.783 133.512 131.040 1.00 41.99  ?  467 TYR B CE2 1 
ATOM   8779  C CZ  . TYR B 1 478 ? 150.173 134.609 131.769 1.00 41.99  ?  467 TYR B CZ  1 
ATOM   8780  O OH  . TYR B 1 478 ? 150.968 135.564 131.185 1.00 41.99  ?  467 TYR B OH  1 
ATOM   8781  N N   . ASP B 1 479 ? 147.062 128.665 134.644 1.00 44.54  ?  468 ASP B N   1 
ATOM   8782  C CA  . ASP B 1 479 ? 146.197 127.737 135.359 1.00 44.54  ?  468 ASP B CA  1 
ATOM   8783  C C   . ASP B 1 479 ? 146.991 126.887 136.339 1.00 44.54  ?  468 ASP B C   1 
ATOM   8784  O O   . ASP B 1 479 ? 146.471 126.495 137.390 1.00 44.54  ?  468 ASP B O   1 
ATOM   8785  C CB  . ASP B 1 479 ? 145.432 126.867 134.369 1.00 44.54  ?  468 ASP B CB  1 
ATOM   8786  C CG  . ASP B 1 479 ? 144.345 127.635 133.649 1.00 44.54  ?  468 ASP B CG  1 
ATOM   8787  O OD1 . ASP B 1 479 ? 143.274 127.865 134.248 1.00 44.54  ?  468 ASP B OD1 1 
ATOM   8788  O OD2 . ASP B 1 479 ? 144.557 128.011 132.482 1.00 44.54  -1 468 ASP B OD2 1 
ATOM   8789  N N   . CYS B 1 480 ? 148.259 126.604 136.030 1.00 45.47  ?  469 CYS B N   1 
ATOM   8790  C CA  . CYS B 1 480 ? 149.125 125.970 137.018 1.00 45.47  ?  469 CYS B CA  1 
ATOM   8791  C C   . CYS B 1 480 ? 149.346 126.891 138.207 1.00 45.47  ?  469 CYS B C   1 
ATOM   8792  O O   . CYS B 1 480 ? 149.388 126.440 139.357 1.00 45.47  ?  469 CYS B O   1 
ATOM   8793  C CB  . CYS B 1 480 ? 150.460 125.587 136.387 1.00 45.47  ?  469 CYS B CB  1 
ATOM   8794  S SG  . CYS B 1 480 ? 151.543 124.638 137.466 1.00 45.47  ?  469 CYS B SG  1 
ATOM   8795  N N   . LEU B 1 481 ? 149.477 128.190 137.949 1.00 41.38  ?  470 LEU B N   1 
ATOM   8796  C CA  . LEU B 1 481 ? 149.591 129.151 139.035 1.00 41.38  ?  470 LEU B CA  1 
ATOM   8797  C C   . LEU B 1 481 ? 148.313 129.206 139.858 1.00 41.38  ?  470 LEU B C   1 
ATOM   8798  O O   . LEU B 1 481 ? 148.366 129.282 141.087 1.00 41.38  ?  470 LEU B O   1 
ATOM   8799  C CB  . LEU B 1 481 ? 149.932 130.524 138.461 1.00 41.38  ?  470 LEU B CB  1 
ATOM   8800  C CG  . LEU B 1 481 ? 150.359 131.637 139.408 1.00 41.38  ?  470 LEU B CG  1 
ATOM   8801  C CD1 . LEU B 1 481 ? 151.607 131.244 140.167 1.00 41.38  ?  470 LEU B CD1 1 
ATOM   8802  C CD2 . LEU B 1 481 ? 150.591 132.894 138.607 1.00 41.38  ?  470 LEU B CD2 1 
ATOM   8803  N N   . ILE B 1 482 ? 147.154 129.174 139.197 1.00 41.34  ?  471 ILE B N   1 
ATOM   8804  C CA  . ILE B 1 482 ? 145.882 129.147 139.919 1.00 41.34  ?  471 ILE B CA  1 
ATOM   8805  C C   . ILE B 1 482 ? 145.805 127.914 140.813 1.00 41.34  ?  471 ILE B C   1 
ATOM   8806  O O   . ILE B 1 482 ? 145.443 128.001 141.989 1.00 41.34  ?  471 ILE B O   1 
ATOM   8807  C CB  . ILE B 1 482 ? 144.698 129.200 138.939 1.00 41.34  ?  471 ILE B CB  1 
ATOM   8808  C CG1 . ILE B 1 482 ? 144.611 130.568 138.274 1.00 41.34  ?  471 ILE B CG1 1 
ATOM   8809  C CG2 . ILE B 1 482 ? 143.404 128.913 139.660 1.00 41.34  ?  471 ILE B CG2 1 
ATOM   8810  C CD1 . ILE B 1 482 ? 143.548 130.645 137.216 1.00 41.34  ?  471 ILE B CD1 1 
ATOM   8811  N N   . TRP B 1 483 ? 146.176 126.782 140.327 1.00 42.04  ?  472 TRP B N   1 
ATOM   8812  C CA  . TRP B 1 483 ? 146.116 125.535 141.085 1.00 42.04  ?  472 TRP B CA  1 
ATOM   8813  C C   . TRP B 1 483 ? 147.054 125.532 142.255 1.00 42.04  ?  472 TRP B C   1 
ATOM   8814  O O   . TRP B 1 483 ? 146.683 125.191 143.370 1.00 42.04  ?  472 TRP B O   1 
ATOM   8815  C CB  . TRP B 1 483 ? 146.507 124.381 140.162 1.00 42.04  ?  472 TRP B CB  1 
ATOM   8816  C CG  . TRP B 1 483 ? 146.186 123.000 140.663 1.00 42.04  ?  472 TRP B CG  1 
ATOM   8817  C CD1 . TRP B 1 483 ? 145.212 122.173 140.193 1.00 42.04  ?  472 TRP B CD1 1 
ATOM   8818  C CD2 . TRP B 1 483 ? 146.851 122.279 141.710 1.00 42.04  ?  472 TRP B CD2 1 
ATOM   8819  N NE1 . TRP B 1 483 ? 145.219 120.989 140.884 1.00 42.04  ?  472 TRP B NE1 1 
ATOM   8820  C CE2 . TRP B 1 483 ? 146.215 121.028 141.822 1.00 42.04  ?  472 TRP B CE2 1 
ATOM   8821  C CE3 . TRP B 1 483 ? 147.916 122.570 142.567 1.00 42.04  ?  472 TRP B CE3 1 
ATOM   8822  C CZ2 . TRP B 1 483 ? 146.608 120.071 142.753 1.00 42.04  ?  472 TRP B CZ2 1 
ATOM   8823  C CZ3 . TRP B 1 483 ? 148.301 121.621 143.494 1.00 42.04  ?  472 TRP B CZ3 1 
ATOM   8824  C CH2 . TRP B 1 483 ? 147.650 120.387 143.579 1.00 42.04  ?  472 TRP B CH2 1 
ATOM   8825  N N   . ILE B 1 484 ? 148.334 125.865 141.953 1.00 42.21  ?  473 ILE B N   1 
ATOM   8826  C CA  . ILE B 1 484 ? 149.296 125.858 143.051 1.00 42.21  ?  473 ILE B CA  1 
ATOM   8827  C C   . ILE B 1 484 ? 148.944 126.867 144.158 1.00 42.21  ?  473 ILE B C   1 
ATOM   8828  O O   . ILE B 1 484 ? 149.053 126.555 145.342 1.00 42.21  ?  473 ILE B O   1 
ATOM   8829  C CB  . ILE B 1 484 ? 150.734 126.108 142.555 1.00 42.21  ?  473 ILE B CB  1 
ATOM   8830  C CG1 . ILE B 1 484 ? 151.182 124.964 141.648 1.00 42.21  ?  473 ILE B CG1 1 
ATOM   8831  C CG2 . ILE B 1 484 ? 151.688 126.267 143.727 1.00 42.21  ?  473 ILE B CG2 1 
ATOM   8832  C CD1 . ILE B 1 484 ? 152.499 125.217 140.953 1.00 42.21  ?  473 ILE B CD1 1 
ATOM   8833  N N   . MET B 1 485 ? 148.519 128.063 143.778 1.00 41.24  ?  474 MET B N   1 
ATOM   8834  C CA  . MET B 1 485 ? 148.150 129.084 144.757 1.00 41.24  ?  474 MET B CA  1 
ATOM   8835  C C   . MET B 1 485 ? 146.922 128.714 145.576 1.00 41.24  ?  474 MET B C   1 
ATOM   8836  O O   . MET B 1 485 ? 146.881 128.962 146.775 1.00 41.24  ?  474 MET B O   1 
ATOM   8837  C CB  . MET B 1 485 ? 147.920 130.433 144.066 1.00 41.24  ?  474 MET B CB  1 
ATOM   8838  C CG  . MET B 1 485 ? 149.174 131.043 143.470 1.00 41.24  ?  474 MET B CG  1 
ATOM   8839  S SD  . MET B 1 485 ? 150.475 131.284 144.693 1.00 41.24  ?  474 MET B SD  1 
ATOM   8840  C CE  . MET B 1 485 ? 149.661 132.396 145.835 1.00 41.24  ?  474 MET B CE  1 
ATOM   8841  N N   . THR B 1 486 ? 145.922 128.122 144.935 1.00 40.71  ?  475 THR B N   1 
ATOM   8842  C CA  . THR B 1 486 ? 144.730 127.707 145.660 1.00 40.71  ?  475 THR B CA  1 
ATOM   8843  C C   . THR B 1 486 ? 145.090 126.645 146.688 1.00 40.71  ?  475 THR B C   1 
ATOM   8844  O O   . THR B 1 486 ? 144.587 126.674 147.801 1.00 40.71  ?  475 THR B O   1 
ATOM   8845  C CB  . THR B 1 486 ? 143.581 127.220 144.726 1.00 40.71  ?  475 THR B CB  1 
ATOM   8846  O OG1 . THR B 1 486 ? 142.479 126.760 145.519 1.00 40.71  ?  475 THR B OG1 1 
ATOM   8847  C CG2 . THR B 1 486 ? 144.032 126.099 143.840 1.00 40.71  ?  475 THR B CG2 1 
ATOM   8848  N N   . PHE B 1 487 ? 145.973 125.729 146.330 1.00 41.62  ?  476 PHE B N   1 
ATOM   8849  C CA  . PHE B 1 487 ? 146.378 124.693 147.256 1.00 41.62  ?  476 PHE B CA  1 
ATOM   8850  C C   . PHE B 1 487 ? 147.043 125.305 148.477 1.00 41.62  ?  476 PHE B C   1 
ATOM   8851  O O   . PHE B 1 487 ? 146.712 124.953 149.599 1.00 41.62  ?  476 PHE B O   1 
ATOM   8852  C CB  . PHE B 1 487 ? 147.309 123.692 146.571 1.00 41.62  ?  476 PHE B CB  1 
ATOM   8853  C CG  . PHE B 1 487 ? 147.736 122.561 147.453 1.00 41.62  ?  476 PHE B CG  1 
ATOM   8854  C CD1 . PHE B 1 487 ? 146.975 121.410 147.540 1.00 41.62  ?  476 PHE B CD1 1 
ATOM   8855  C CD2 . PHE B 1 487 ? 148.901 122.645 148.194 1.00 41.62  ?  476 PHE B CD2 1 
ATOM   8856  C CE1 . PHE B 1 487 ? 147.363 120.366 148.353 1.00 41.62  ?  476 PHE B CE1 1 
ATOM   8857  C CE2 . PHE B 1 487 ? 149.298 121.603 149.008 1.00 41.62  ?  476 PHE B CE2 1 
ATOM   8858  C CZ  . PHE B 1 487 ? 148.527 120.462 149.088 1.00 41.62  ?  476 PHE B CZ  1 
ATOM   8859  N N   . ILE B 1 488 ? 147.966 126.235 148.262 1.00 41.21  ?  477 ILE B N   1 
ATOM   8860  C CA  . ILE B 1 488 ? 148.656 126.878 149.368 1.00 41.21  ?  477 ILE B CA  1 
ATOM   8861  C C   . ILE B 1 488 ? 147.703 127.692 150.235 1.00 41.21  ?  477 ILE B C   1 
ATOM   8862  O O   . ILE B 1 488 ? 147.709 127.551 151.450 1.00 41.21  ?  477 ILE B O   1 
ATOM   8863  C CB  . ILE B 1 488 ? 149.803 127.774 148.856 1.00 41.21  ?  477 ILE B CB  1 
ATOM   8864  C CG1 . ILE B 1 488 ? 150.845 126.929 148.125 1.00 41.21  ?  477 ILE B CG1 1 
ATOM   8865  C CG2 . ILE B 1 488 ? 150.438 128.540 150.004 1.00 41.21  ?  477 ILE B CG2 1 
ATOM   8866  C CD1 . ILE B 1 488 ? 151.912 127.742 147.430 1.00 41.21  ?  477 ILE B CD1 1 
ATOM   8867  N N   . PHE B 1 489 ? 146.869 128.520 149.617 1.00 41.92  ?  478 PHE B N   1 
ATOM   8868  C CA  . PHE B 1 489 ? 145.896 129.296 150.374 1.00 41.92  ?  478 PHE B CA  1 
ATOM   8869  C C   . PHE B 1 489 ? 144.976 128.402 151.191 1.00 41.92  ?  478 PHE B C   1 
ATOM   8870  O O   . PHE B 1 489 ? 144.677 128.706 152.338 1.00 41.92  ?  478 PHE B O   1 
ATOM   8871  C CB  . PHE B 1 489 ? 145.042 130.174 149.454 1.00 41.92  ?  478 PHE B CB  1 
ATOM   8872  C CG  . PHE B 1 489 ? 145.757 131.357 148.884 1.00 41.92  ?  478 PHE B CG  1 
ATOM   8873  C CD1 . PHE B 1 489 ? 146.656 132.078 149.648 1.00 41.92  ?  478 PHE B CD1 1 
ATOM   8874  C CD2 . PHE B 1 489 ? 145.503 131.769 147.588 1.00 41.92  ?  478 PHE B CD2 1 
ATOM   8875  C CE1 . PHE B 1 489 ? 147.304 133.177 149.122 1.00 41.92  ?  478 PHE B CE1 1 
ATOM   8876  C CE2 . PHE B 1 489 ? 146.145 132.867 147.055 1.00 41.92  ?  478 PHE B CE2 1 
ATOM   8877  C CZ  . PHE B 1 489 ? 147.048 133.572 147.824 1.00 41.92  ?  478 PHE B CZ  1 
ATOM   8878  N N   . THR B 1 490 ? 144.517 127.305 150.606 1.00 41.28  ?  479 THR B N   1 
ATOM   8879  C CA  . THR B 1 490 ? 143.573 126.443 151.306 1.00 41.28  ?  479 THR B CA  1 
ATOM   8880  C C   . THR B 1 490 ? 144.258 125.762 152.475 1.00 41.28  ?  479 THR B C   1 
ATOM   8881  O O   . THR B 1 490 ? 143.683 125.641 153.545 1.00 41.28  ?  479 THR B O   1 
ATOM   8882  C CB  . THR B 1 490 ? 142.937 125.406 150.362 1.00 41.28  ?  479 THR B CB  1 
ATOM   8883  O OG1 . THR B 1 490 ? 142.408 126.073 149.209 1.00 41.28  ?  479 THR B OG1 1 
ATOM   8884  C CG2 . THR B 1 490 ? 141.820 124.655 151.067 1.00 41.28  ?  479 THR B CG2 1 
ATOM   8885  N N   . ILE B 1 491 ? 145.489 125.331 152.279 1.00 42.25  ?  480 ILE B N   1 
ATOM   8886  C CA  . ILE B 1 491 ? 146.243 124.711 153.360 1.00 42.25  ?  480 ILE B CA  1 
ATOM   8887  C C   . ILE B 1 491 ? 146.589 125.684 154.477 1.00 42.25  ?  480 ILE B C   1 
ATOM   8888  O O   . ILE B 1 491 ? 146.488 125.338 155.649 1.00 42.25  ?  480 ILE B O   1 
ATOM   8889  C CB  . ILE B 1 491 ? 147.550 124.091 152.835 1.00 42.25  ?  480 ILE B CB  1 
ATOM   8890  C CG1 . ILE B 1 491 ? 147.250 122.942 151.872 1.00 42.25  ?  480 ILE B CG1 1 
ATOM   8891  C CG2 . ILE B 1 491 ? 148.414 123.606 153.987 1.00 42.25  ?  480 ILE B CG2 1 
ATOM   8892  C CD1 . ILE B 1 491 ? 146.517 121.784 152.510 1.00 42.25  ?  480 ILE B CD1 1 
ATOM   8893  N N   . VAL B 1 492 ? 146.984 126.900 154.131 1.00 44.35  ?  481 VAL B N   1 
ATOM   8894  C CA  . VAL B 1 492 ? 147.426 127.851 155.146 1.00 44.35  ?  481 VAL B CA  1 
ATOM   8895  C C   . VAL B 1 492 ? 146.306 128.675 155.766 1.00 44.35  ?  481 VAL B C   1 
ATOM   8896  O O   . VAL B 1 492 ? 146.272 128.857 156.977 1.00 44.35  ?  481 VAL B O   1 
ATOM   8897  C CB  . VAL B 1 492 ? 148.490 128.803 154.557 1.00 44.35  ?  481 VAL B CB  1 
ATOM   8898  C CG1 . VAL B 1 492 ? 148.890 129.856 155.578 1.00 44.35  ?  481 VAL B CG1 1 
ATOM   8899  C CG2 . VAL B 1 492 ? 149.701 128.013 154.090 1.00 44.35  ?  481 VAL B CG2 1 
ATOM   8900  N N   . LEU B 1 493 ? 145.391 129.173 154.946 1.00 44.42  ?  482 LEU B N   1 
ATOM   8901  C CA  . LEU B 1 493 ? 144.306 130.012 155.449 1.00 44.42  ?  482 LEU B CA  1 
ATOM   8902  C C   . LEU B 1 493 ? 143.084 129.202 155.824 1.00 44.42  ?  482 LEU B C   1 
ATOM   8903  O O   . LEU B 1 493 ? 142.217 129.688 156.534 1.00 44.42  ?  482 LEU B O   1 
ATOM   8904  C CB  . LEU B 1 493 ? 143.918 131.057 154.407 1.00 44.42  ?  482 LEU B CB  1 
ATOM   8905  C CG  . LEU B 1 493 ? 145.045 131.918 153.847 1.00 44.42  ?  482 LEU B CG  1 
ATOM   8906  C CD1 . LEU B 1 493 ? 144.524 132.811 152.734 1.00 44.42  ?  482 LEU B CD1 1 
ATOM   8907  C CD2 . LEU B 1 493 ? 145.682 132.739 154.956 1.00 44.42  ?  482 LEU B CD2 1 
ATOM   8908  N N   . GLY B 1 494 ? 143.010 127.969 155.346 1.00 46.07  ?  483 GLY B N   1 
ATOM   8909  C CA  . GLY B 1 494 ? 141.852 127.148 155.619 1.00 46.07  ?  483 GLY B CA  1 
ATOM   8910  C C   . GLY B 1 494 ? 140.882 127.049 154.469 1.00 46.07  ?  483 GLY B C   1 
ATOM   8911  O O   . GLY B 1 494 ? 141.057 127.707 153.449 1.00 46.07  ?  483 GLY B O   1 
ATOM   8912  N N   . LEU B 1 495 ? 139.847 126.242 154.632 1.00 45.35  ?  484 LEU B N   1 
ATOM   8913  C CA  . LEU B 1 495 ? 138.888 126.021 153.560 1.00 45.35  ?  484 LEU B CA  1 
ATOM   8914  C C   . LEU B 1 495 ? 138.091 127.266 153.173 1.00 45.35  ?  484 LEU B C   1 
ATOM   8915  O O   . LEU B 1 495 ? 137.939 127.557 151.993 1.00 45.35  ?  484 LEU B O   1 
ATOM   8916  C CB  . LEU B 1 495 ? 137.948 124.887 153.964 1.00 45.35  ?  484 LEU B CB  1 
ATOM   8917  C CG  . LEU B 1 495 ? 138.662 123.598 154.381 1.00 45.35  ?  484 LEU B CG  1 
ATOM   8918  C CD1 . LEU B 1 495 ? 137.695 122.589 154.977 1.00 45.35  ?  484 LEU B CD1 1 
ATOM   8919  C CD2 . LEU B 1 495 ? 139.422 122.999 153.211 1.00 45.35  ?  484 LEU B CD2 1 
ATOM   8920  N N   . GLY B 1 496 ? 137.577 127.997 154.154 1.00 46.36  ?  485 GLY B N   1 
ATOM   8921  C CA  . GLY B 1 496 ? 136.790 129.181 153.866 1.00 46.36  ?  485 GLY B CA  1 
ATOM   8922  C C   . GLY B 1 496 ? 137.568 130.371 153.353 1.00 46.36  ?  485 GLY B C   1 
ATOM   8923  O O   . GLY B 1 496 ? 137.230 130.933 152.316 1.00 46.36  ?  485 GLY B O   1 
ATOM   8924  N N   . LEU B 1 497 ? 138.616 130.753 154.094 1.00 46.78  ?  486 LEU B N   1 
ATOM   8925  C CA  . LEU B 1 497 ? 139.418 131.905 153.703 1.00 46.78  ?  486 LEU B CA  1 
ATOM   8926  C C   . LEU B 1 497 ? 140.302 131.583 152.508 1.00 46.78  ?  486 LEU B C   1 
ATOM   8927  O O   . LEU B 1 497 ? 140.536 132.446 151.669 1.00 46.78  ?  486 LEU B O   1 
ATOM   8928  C CB  . LEU B 1 497 ? 140.250 132.398 154.887 1.00 46.78  ?  486 LEU B CB  1 
ATOM   8929  C CG  . LEU B 1 497 ? 141.002 133.710 154.686 1.00 46.78  ?  486 LEU B CG  1 
ATOM   8930  C CD1 . LEU B 1 497 ? 140.021 134.833 154.387 1.00 46.78  ?  486 LEU B CD1 1 
ATOM   8931  C CD2 . LEU B 1 497 ? 141.833 134.034 155.916 1.00 46.78  ?  486 LEU B CD2 1 
ATOM   8932  N N   . GLY B 1 498 ? 140.774 130.357 152.408 1.00 43.34  ?  487 GLY B N   1 
ATOM   8933  C CA  . GLY B 1 498 ? 141.588 129.946 151.283 1.00 43.34  ?  487 GLY B CA  1 
ATOM   8934  C C   . GLY B 1 498 ? 140.845 130.094 149.979 1.00 43.34  ?  487 GLY B C   1 
ATOM   8935  O O   . GLY B 1 498 ? 141.439 130.442 148.972 1.00 43.34  ?  487 GLY B O   1 
ATOM   8936  N N   . LEU B 1 499 ? 139.544 129.837 149.995 1.00 43.07  ?  488 LEU B N   1 
ATOM   8937  C CA  . LEU B 1 499 ? 138.735 129.983 148.790 1.00 43.07  ?  488 LEU B CA  1 
ATOM   8938  C C   . LEU B 1 499 ? 138.535 131.446 148.334 1.00 43.07  ?  488 LEU B C   1 
ATOM   8939  O O   . LEU B 1 499 ? 138.614 131.717 147.146 1.00 43.07  ?  488 LEU B O   1 
ATOM   8940  C CB  . LEU B 1 499 ? 137.380 129.294 148.975 1.00 43.07  ?  488 LEU B CB  1 
ATOM   8941  C CG  . LEU B 1 499 ? 136.559 129.134 147.695 1.00 43.07  ?  488 LEU B CG  1 
ATOM   8942  C CD1 . LEU B 1 499 ? 137.267 128.200 146.726 1.00 43.07  ?  488 LEU B CD1 1 
ATOM   8943  C CD2 . LEU B 1 499 ? 135.163 128.625 148.009 1.00 43.07  ?  488 LEU B CD2 1 
ATOM   8944  N N   . ALA B 1 500 ? 138.285 132.378 149.254 1.00 41.56  ?  489 ALA B N   1 
ATOM   8945  C CA  . ALA B 1 500 ? 138.128 133.778 148.878 1.00 41.56  ?  489 ALA B CA  1 
ATOM   8946  C C   . ALA B 1 500 ? 139.414 134.335 148.280 1.00 41.56  ?  489 ALA B C   1 
ATOM   8947  O O   . ALA B 1 500 ? 139.391 134.969 147.215 1.00 41.56  ?  489 ALA B O   1 
ATOM   8948  C CB  . ALA B 1 500 ? 137.697 134.600 150.089 1.00 41.56  ?  489 ALA B CB  1 
ATOM   8949  N N   . ALA B 1 501 ? 140.546 134.103 148.950 1.00 41.44  ?  490 ALA B N   1 
ATOM   8950  C CA  . ALA B 1 501 ? 141.821 134.551 148.402 1.00 41.44  ?  490 ALA B CA  1 
ATOM   8951  C C   . ALA B 1 501 ? 142.103 133.887 147.063 1.00 41.44  ?  490 ALA B C   1 
ATOM   8952  O O   . ALA B 1 501 ? 142.678 134.506 146.159 1.00 41.44  ?  490 ALA B O   1 
ATOM   8953  C CB  . ALA B 1 501 ? 142.943 134.264 149.396 1.00 41.44  ?  490 ALA B CB  1 
ATOM   8954  N N   . SER B 1 502 ? 141.663 132.639 146.901 1.00 41.76  ?  491 SER B N   1 
ATOM   8955  C CA  . SER B 1 502 ? 141.903 131.897 145.672 1.00 41.76  ?  491 SER B CA  1 
ATOM   8956  C C   . SER B 1 502 ? 141.094 132.461 144.515 1.00 41.76  ?  491 SER B C   1 
ATOM   8957  O O   . SER B 1 502 ? 141.595 132.556 143.391 1.00 41.76  ?  491 SER B O   1 
ATOM   8958  C CB  . SER B 1 502 ? 141.552 130.436 145.900 1.00 41.76  ?  491 SER B CB  1 
ATOM   8959  O OG  . SER B 1 502 ? 142.459 129.846 146.807 1.00 41.76  ?  491 SER B OG  1 
ATOM   8960  N N   . VAL B 1 503 ? 139.838 132.828 144.766 1.00 40.58  ?  492 VAL B N   1 
ATOM   8961  C CA  . VAL B 1 503 ? 139.024 133.440 143.721 1.00 40.58  ?  492 VAL B CA  1 
ATOM   8962  C C   . VAL B 1 503 ? 139.582 134.805 143.347 1.00 40.58  ?  492 VAL B C   1 
ATOM   8963  O O   . VAL B 1 503 ? 139.613 135.176 142.166 1.00 40.58  ?  492 VAL B O   1 
ATOM   8964  C CB  . VAL B 1 503 ? 137.554 133.529 144.166 1.00 40.58  ?  492 VAL B CB  1 
ATOM   8965  C CG1 . VAL B 1 503 ? 136.727 134.249 143.121 1.00 40.58  ?  492 VAL B CG1 1 
ATOM   8966  C CG2 . VAL B 1 503 ? 137.001 132.149 144.399 1.00 40.58  ?  492 VAL B CG2 1 
ATOM   8967  N N   . ALA B 1 504 ? 140.053 135.567 144.336 1.00 40.50  ?  493 ALA B N   1 
ATOM   8968  C CA  . ALA B 1 504 ? 140.665 136.857 144.026 1.00 40.50  ?  493 ALA B CA  1 
ATOM   8969  C C   . ALA B 1 504 ? 141.904 136.689 143.153 1.00 40.50  ?  493 ALA B C   1 
ATOM   8970  O O   . ALA B 1 504 ? 142.075 137.403 142.158 1.00 40.50  ?  493 ALA B O   1 
ATOM   8971  C CB  . ALA B 1 504 ? 141.007 137.594 145.318 1.00 40.50  ?  493 ALA B CB  1 
ATOM   8972  N N   . PHE B 1 505 ? 142.770 135.733 143.491 1.00 41.03  ?  494 PHE B N   1 
ATOM   8973  C CA  . PHE B 1 505 ? 143.968 135.523 142.683 1.00 41.03  ?  494 PHE B CA  1 
ATOM   8974  C C   . PHE B 1 505 ? 143.632 134.976 141.300 1.00 41.03  ?  494 PHE B C   1 
ATOM   8975  O O   . PHE B 1 505 ? 144.331 135.279 140.324 1.00 41.03  ?  494 PHE B O   1 
ATOM   8976  C CB  . PHE B 1 505 ? 144.930 134.588 143.406 1.00 41.03  ?  494 PHE B CB  1 
ATOM   8977  C CG  . PHE B 1 505 ? 146.277 134.499 142.763 1.00 41.03  ?  494 PHE B CG  1 
ATOM   8978  C CD1 . PHE B 1 505 ? 146.560 133.500 141.850 1.00 41.03  ?  494 PHE B CD1 1 
ATOM   8979  C CD2 . PHE B 1 505 ? 147.257 135.423 143.058 1.00 41.03  ?  494 PHE B CD2 1 
ATOM   8980  C CE1 . PHE B 1 505 ? 147.790 133.428 141.253 1.00 41.03  ?  494 PHE B CE1 1 
ATOM   8981  C CE2 . PHE B 1 505 ? 148.487 135.351 142.465 1.00 41.03  ?  494 PHE B CE2 1 
ATOM   8982  C CZ  . PHE B 1 505 ? 148.756 134.353 141.564 1.00 41.03  ?  494 PHE B CZ  1 
ATOM   8983  N N   . GLN B 1 506 ? 142.526 134.150 141.273 1.00 39.37  ?  495 GLN B N   1 
ATOM   8984  C CA  . GLN B 1 506 ? 142.102 133.637 139.993 1.00 39.37  ?  495 GLN B CA  1 
ATOM   8985  C C   . GLN B 1 506 ? 141.664 134.786 139.078 1.00 39.37  ?  495 GLN B C   1 
ATOM   8986  O O   . GLN B 1 506 ? 141.946 134.765 137.886 1.00 39.37  ?  495 GLN B O   1 
ATOM   8987  C CB  . GLN B 1 506 ? 141.002 132.607 140.192 1.00 39.37  ?  495 GLN B CB  1 
ATOM   8988  C CG  . GLN B 1 506 ? 140.264 132.179 138.947 1.00 39.37  ?  495 GLN B CG  1 
ATOM   8989  C CD  . GLN B 1 506 ? 138.867 131.717 139.286 1.00 39.37  ?  495 GLN B CD  1 
ATOM   8990  O OE1 . GLN B 1 506 ? 138.250 132.220 140.221 1.00 39.37  ?  495 GLN B OE1 1 
ATOM   8991  N NE2 . GLN B 1 506 ? 138.362 130.763 138.531 1.00 39.37  ?  495 GLN B NE2 1 
ATOM   8992  N N   . LEU B 1 507 ? 141.079 135.807 139.600 1.00 39.40  ?  496 LEU B N   1 
ATOM   8993  C CA  . LEU B 1 507 ? 140.636 136.934 138.801 1.00 39.40  ?  496 LEU B CA  1 
ATOM   8994  C C   . LEU B 1 507 ? 141.852 137.750 138.397 1.00 39.40  ?  496 LEU B C   1 
ATOM   8995  O O   . LEU B 1 507 ? 141.862 138.368 137.340 1.00 39.40  ?  496 LEU B O   1 
ATOM   8996  C CB  . LEU B 1 507 ? 139.657 137.796 139.579 1.00 39.40  ?  496 LEU B CB  1 
ATOM   8997  C CG  . LEU B 1 507 ? 138.364 137.117 140.020 1.00 39.40  ?  496 LEU B CG  1 
ATOM   8998  C CD1 . LEU B 1 507 ? 137.482 138.105 140.766 1.00 39.40  ?  496 LEU B CD1 1 
ATOM   8999  C CD2 . LEU B 1 507 ? 137.634 136.534 138.823 1.00 39.40  ?  496 LEU B CD2 1 
ATOM   9000  N N   . LEU B 1 508 ? 142.882 137.747 139.233 1.00 39.40  ?  497 LEU B N   1 
ATOM   9001  C CA  . LEU B 1 508 ? 144.092 138.509 138.944 1.00 39.40  ?  497 LEU B CA  1 
ATOM   9002  C C   . LEU B 1 508 ? 144.927 137.905 137.816 1.00 39.40  ?  497 LEU B C   1 
ATOM   9003  O O   . LEU B 1 508 ? 145.688 138.609 137.164 1.00 39.40  ?  497 LEU B O   1 
ATOM   9004  C CB  . LEU B 1 508 ? 144.938 138.656 140.213 1.00 39.40  ?  497 LEU B CB  1 
ATOM   9005  C CG  . LEU B 1 508 ? 146.164 139.561 140.135 1.00 39.40  ?  497 LEU B CG  1 
ATOM   9006  C CD1 . LEU B 1 508 ? 145.797 140.943 139.616 1.00 39.40  ?  497 LEU B CD1 1 
ATOM   9007  C CD2 . LEU B 1 508 ? 146.844 139.651 141.491 1.00 39.40  ?  497 LEU B CD2 1 
ATOM   9008  N N   . THR B 1 509 ? 144.796 136.609 137.592 1.00 38.91  ?  498 THR B N   1 
ATOM   9009  C CA  . THR B 1 509 ? 145.538 135.950 136.525 1.00 38.91  ?  498 THR B CA  1 
ATOM   9010  C C   . THR B 1 509 ? 145.028 136.381 135.159 1.00 38.91  ?  498 THR B C   1 
ATOM   9011  O O   . THR B 1 509 ? 145.773 136.340 134.191 1.00 38.91  ?  498 THR B O   1 
ATOM   9012  C CB  . THR B 1 509 ? 145.481 134.419 136.667 1.00 38.91  ?  498 THR B CB  1 
ATOM   9013  O OG1 . THR B 1 509 ? 144.114 133.993 136.717 1.00 38.91  ?  498 THR B OG1 1 
ATOM   9014  C CG2 . THR B 1 509 ? 146.191 133.981 137.933 1.00 38.91  ?  498 THR B CG2 1 
ATOM   9015  N N   . ILE B 1 510 ? 143.778 136.814 135.109 1.00 39.50  ?  499 ILE B N   1 
ATOM   9016  C CA  . ILE B 1 510 ? 143.180 137.279 133.883 1.00 39.50  ?  499 ILE B CA  1 
ATOM   9017  C C   . ILE B 1 510 ? 143.880 138.566 133.477 1.00 39.50  ?  499 ILE B C   1 
ATOM   9018  O O   . ILE B 1 510 ? 144.113 138.804 132.315 1.00 39.50  ?  499 ILE B O   1 
ATOM   9019  C CB  . ILE B 1 510 ? 141.656 137.468 134.018 1.00 39.50  ?  499 ILE B CB  1 
ATOM   9020  C CG1 . ILE B 1 510 ? 140.964 136.128 134.269 1.00 39.50  ?  499 ILE B CG1 1 
ATOM   9021  C CG2 . ILE B 1 510 ? 141.069 138.101 132.770 1.00 39.50  ?  499 ILE B CG2 1 
ATOM   9022  C CD1 . ILE B 1 510 ? 139.653 136.256 134.999 1.00 39.50  ?  499 ILE B CD1 1 
ATOM   9023  N N   . VAL B 1 511 ? 144.226 139.381 134.459 1.00 38.78  ?  500 VAL B N   1 
ATOM   9024  C CA  . VAL B 1 511 ? 144.971 140.586 134.233 1.00 38.78  ?  500 VAL B CA  1 
ATOM   9025  C C   . VAL B 1 511 ? 146.413 140.232 133.879 1.00 38.78  ?  500 VAL B C   1 
ATOM   9026  O O   . VAL B 1 511 ? 146.988 140.870 133.048 1.00 38.78  ?  500 VAL B O   1 
ATOM   9027  C CB  . VAL B 1 511 ? 144.896 141.531 135.438 1.00 38.78  ?  500 VAL B CB  1 
ATOM   9028  C CG1 . VAL B 1 511 ? 145.798 142.726 135.227 1.00 38.78  ?  500 VAL B CG1 1 
ATOM   9029  C CG2 . VAL B 1 511 ? 143.472 141.977 135.667 1.00 38.78  ?  500 VAL B CG2 1 
ATOM   9030  N N   . PHE B 1 512 ? 146.997 139.222 134.509 1.00 38.29  ?  501 PHE B N   1 
ATOM   9031  C CA  . PHE B 1 512 ? 148.348 138.761 134.197 1.00 38.29  ?  501 PHE B CA  1 
ATOM   9032  C C   . PHE B 1 512 ? 148.452 138.305 132.754 1.00 38.29  ?  501 PHE B C   1 
ATOM   9033  O O   . PHE B 1 512 ? 149.449 138.556 132.093 1.00 38.29  ?  501 PHE B O   1 
ATOM   9034  C CB  . PHE B 1 512 ? 148.762 137.619 135.124 1.00 38.29  ?  501 PHE B CB  1 
ATOM   9035  C CG  . PHE B 1 512 ? 148.935 138.018 136.556 1.00 38.29  ?  501 PHE B CG  1 
ATOM   9036  C CD1 . PHE B 1 512 ? 149.101 139.344 136.910 1.00 38.29  ?  501 PHE B CD1 1 
ATOM   9037  C CD2 . PHE B 1 512 ? 148.952 137.055 137.550 1.00 38.29  ?  501 PHE B CD2 1 
ATOM   9038  C CE1 . PHE B 1 512 ? 149.266 139.703 138.233 1.00 38.29  ?  501 PHE B CE1 1 
ATOM   9039  C CE2 . PHE B 1 512 ? 149.117 137.406 138.873 1.00 38.29  ?  501 PHE B CE2 1 
ATOM   9040  C CZ  . PHE B 1 512 ? 149.277 138.733 139.213 1.00 38.29  ?  501 PHE B CZ  1 
ATOM   9041  N N   . ARG B 1 513 ? 147.417 137.637 132.262 1.00 40.74  ?  502 ARG B N   1 
ATOM   9042  C CA  . ARG B 1 513 ? 147.405 137.160 130.889 1.00 40.74  ?  502 ARG B CA  1 
ATOM   9043  C C   . ARG B 1 513 ? 147.346 138.281 129.871 1.00 40.74  ?  502 ARG B C   1 
ATOM   9044  O O   . ARG B 1 513 ? 147.874 138.147 128.776 1.00 40.74  ?  502 ARG B O   1 
ATOM   9045  C CB  . ARG B 1 513 ? 146.201 136.248 130.667 1.00 40.74  ?  502 ARG B CB  1 
ATOM   9046  C CG  . ARG B 1 513 ? 146.199 134.937 131.425 1.00 40.74  ?  502 ARG B CG  1 
ATOM   9047  C CD  . ARG B 1 513 ? 144.915 134.186 131.114 1.00 40.74  ?  502 ARG B CD  1 
ATOM   9048  N NE  . ARG B 1 513 ? 144.776 132.949 131.873 1.00 40.74  ?  502 ARG B NE  1 
ATOM   9049  C CZ  . ARG B 1 513 ? 145.124 131.749 131.422 1.00 40.74  ?  502 ARG B CZ  1 
ATOM   9050  N NH1 . ARG B 1 513 ? 144.955 130.680 132.187 1.00 40.74  1  502 ARG B NH1 1 
ATOM   9051  N NH2 . ARG B 1 513 ? 145.638 131.615 130.209 1.00 40.74  ?  502 ARG B NH2 1 
ATOM   9052  N N   . THR B 1 514 ? 146.702 139.383 130.213 1.00 39.87  ?  503 THR B N   1 
ATOM   9053  C CA  . THR B 1 514 ? 146.521 140.471 129.256 1.00 39.87  ?  503 THR B CA  1 
ATOM   9054  C C   . THR B 1 514 ? 147.312 141.728 129.590 1.00 39.87  ?  503 THR B C   1 
ATOM   9055  O O   . THR B 1 514 ? 147.223 142.707 128.873 1.00 39.87  ?  503 THR B O   1 
ATOM   9056  C CB  . THR B 1 514 ? 145.026 140.822 129.160 1.00 39.87  ?  503 THR B CB  1 
ATOM   9057  O OG1 . THR B 1 514 ? 144.483 140.943 130.476 1.00 39.87  ?  503 THR B OG1 1 
ATOM   9058  C CG2 . THR B 1 514 ? 144.277 139.732 128.427 1.00 39.87  ?  503 THR B CG2 1 
ATOM   9059  N N   . GLN B 1 515 ? 148.101 141.698 130.654 1.00 38.99  ?  504 GLN B N   1 
ATOM   9060  C CA  . GLN B 1 515 ? 148.847 142.877 131.107 1.00 38.99  ?  504 GLN B CA  1 
ATOM   9061  C C   . GLN B 1 515 ? 149.917 143.365 130.129 1.00 38.99  ?  504 GLN B C   1 
ATOM   9062  O O   . GLN B 1 515 ? 150.082 144.564 129.941 1.00 38.99  ?  504 GLN B O   1 
ATOM   9063  C CB  . GLN B 1 515 ? 149.473 142.538 132.463 1.00 38.99  ?  504 GLN B CB  1 
ATOM   9064  C CG  . GLN B 1 515 ? 150.292 143.601 133.144 1.00 38.99  ?  504 GLN B CG  1 
ATOM   9065  C CD  . GLN B 1 515 ? 150.732 143.132 134.515 1.00 38.99  ?  504 GLN B CD  1 
ATOM   9066  O OE1 . GLN B 1 515 ? 150.263 142.105 135.005 1.00 38.99  ?  504 GLN B OE1 1 
ATOM   9067  N NE2 . GLN B 1 515 ? 151.625 143.877 135.141 1.00 38.99  ?  504 GLN B NE2 1 
ATOM   9068  N N   . PHE B 1 516 ? 150.652 142.440 129.524 1.00 38.03  ?  505 PHE B N   1 
ATOM   9069  C CA  . PHE B 1 516 ? 151.703 142.803 128.578 1.00 38.03  ?  505 PHE B CA  1 
ATOM   9070  C C   . PHE B 1 516 ? 151.482 142.058 127.282 1.00 38.03  ?  505 PHE B C   1 
ATOM   9071  O O   . PHE B 1 516 ? 152.160 141.076 127.021 1.00 38.03  ?  505 PHE B O   1 
ATOM   9072  C CB  . PHE B 1 516 ? 153.073 142.449 129.138 1.00 38.03  ?  505 PHE B CB  1 
ATOM   9073  C CG  . PHE B 1 516 ? 153.319 142.960 130.526 1.00 38.03  ?  505 PHE B CG  1 
ATOM   9074  C CD1 . PHE B 1 516 ? 153.220 144.307 130.814 1.00 38.03  ?  505 PHE B CD1 1 
ATOM   9075  C CD2 . PHE B 1 516 ? 153.675 142.089 131.540 1.00 38.03  ?  505 PHE B CD2 1 
ATOM   9076  C CE1 . PHE B 1 516 ? 153.454 144.776 132.090 1.00 38.03  ?  505 PHE B CE1 1 
ATOM   9077  C CE2 . PHE B 1 516 ? 153.914 142.551 132.819 1.00 38.03  ?  505 PHE B CE2 1 
ATOM   9078  C CZ  . PHE B 1 516 ? 153.806 143.898 133.094 1.00 38.03  ?  505 PHE B CZ  1 
ATOM   9079  N N   . PRO B 1 517 ? 150.488 142.523 126.499 1.00 42.45  ?  506 PRO B N   1 
ATOM   9080  C CA  . PRO B 1 517 ? 150.162 141.816 125.264 1.00 42.45  ?  506 PRO B CA  1 
ATOM   9081  C C   . PRO B 1 517 ? 151.320 141.869 124.306 1.00 42.45  ?  506 PRO B C   1 
ATOM   9082  O O   . PRO B 1 517 ? 152.041 142.857 124.269 1.00 42.45  ?  506 PRO B O   1 
ATOM   9083  C CB  . PRO B 1 517 ? 148.982 142.616 124.699 1.00 42.45  ?  506 PRO B CB  1 
ATOM   9084  C CG  . PRO B 1 517 ? 148.496 143.472 125.811 1.00 42.45  ?  506 PRO B CG  1 
ATOM   9085  C CD  . PRO B 1 517 ? 149.708 143.769 126.622 1.00 42.45  ?  506 PRO B CD  1 
ATOM   9086  N N   . LYS B 1 518 ? 151.500 140.809 123.534 1.00 47.92  ?  507 LYS B N   1 
ATOM   9087  C CA  . LYS B 1 518 ? 152.564 140.779 122.556 1.00 47.92  ?  507 LYS B CA  1 
ATOM   9088  C C   . LYS B 1 518 ? 152.118 141.541 121.332 1.00 47.92  ?  507 LYS B C   1 
ATOM   9089  O O   . LYS B 1 518 ? 151.638 140.954 120.373 1.00 47.92  ?  507 LYS B O   1 
ATOM   9090  C CB  . LYS B 1 518 ? 152.921 139.341 122.200 1.00 47.92  ?  507 LYS B CB  1 
ATOM   9091  C CG  . LYS B 1 518 ? 153.311 138.486 123.391 1.00 47.92  ?  507 LYS B CG  1 
ATOM   9092  C CD  . LYS B 1 518 ? 153.687 137.081 122.952 1.00 47.92  ?  507 LYS B CD  1 
ATOM   9093  C CE  . LYS B 1 518 ? 154.000 136.197 124.149 1.00 47.92  ?  507 LYS B CE  1 
ATOM   9094  N NZ  . LYS B 1 518 ? 154.346 134.808 123.742 1.00 47.92  1  507 LYS B NZ  1 
ATOM   9095  N N   . CYS B 1 519 ? 152.275 142.853 121.366 1.00 46.14  ?  508 CYS B N   1 
ATOM   9096  C CA  . CYS B 1 519 ? 151.889 143.681 120.240 1.00 46.14  ?  508 CYS B CA  1 
ATOM   9097  C C   . CYS B 1 519 ? 152.870 143.490 119.094 1.00 46.14  ?  508 CYS B C   1 
ATOM   9098  O O   . CYS B 1 519 ? 154.027 143.163 119.321 1.00 46.14  ?  508 CYS B O   1 
ATOM   9099  C CB  . CYS B 1 519 ? 151.820 145.140 120.672 1.00 46.14  ?  508 CYS B CB  1 
ATOM   9100  S SG  . CYS B 1 519 ? 150.680 145.468 122.034 1.00 46.14  ?  508 CYS B SG  1 
ATOM   9101  N N   . SER B 1 520 ? 152.421 143.677 117.864 1.00 43.65  ?  509 SER B N   1 
ATOM   9102  C CA  . SER B 1 520 ? 153.282 143.425 116.720 1.00 43.65  ?  509 SER B CA  1 
ATOM   9103  C C   . SER B 1 520 ? 153.073 144.387 115.581 1.00 43.65  ?  509 SER B C   1 
ATOM   9104  O O   . SER B 1 520 ? 152.043 145.041 115.500 1.00 43.65  ?  509 SER B O   1 
ATOM   9105  C CB  . SER B 1 520 ? 153.055 141.999 116.200 1.00 43.65  ?  509 SER B CB  1 
ATOM   9106  O OG  . SER B 1 520 ? 151.695 141.784 115.874 1.00 43.65  ?  509 SER B OG  1 
ATOM   9107  N N   . THR B 1 521 ? 154.055 144.469 114.698 1.00 45.03  ?  510 THR B N   1 
ATOM   9108  C CA  . THR B 1 521 ? 153.925 145.294 113.519 1.00 45.03  ?  510 THR B CA  1 
ATOM   9109  C C   . THR B 1 521 ? 153.653 144.335 112.390 1.00 45.03  ?  510 THR B C   1 
ATOM   9110  O O   . THR B 1 521 ? 154.260 143.273 112.314 1.00 45.03  ?  510 THR B O   1 
ATOM   9111  C CB  . THR B 1 521 ? 155.191 146.112 113.232 1.00 45.03  ?  510 THR B CB  1 
ATOM   9112  O OG1 . THR B 1 521 ? 155.441 147.000 114.326 1.00 45.03  ?  510 THR B OG1 1 
ATOM   9113  C CG2 . THR B 1 521 ? 155.024 146.923 111.960 1.00 45.03  ?  510 THR B CG2 1 
ATOM   9114  N N   . LEU B 1 522 ? 152.719 144.682 111.523 1.00 43.15  ?  511 LEU B N   1 
ATOM   9115  C CA  . LEU B 1 522 ? 152.348 143.776 110.452 1.00 43.15  ?  511 LEU B CA  1 
ATOM   9116  C C   . LEU B 1 522 ? 152.847 144.237 109.105 1.00 43.15  ?  511 LEU B C   1 
ATOM   9117  O O   . LEU B 1 522 ? 153.144 145.408 108.920 1.00 43.15  ?  511 LEU B O   1 
ATOM   9118  C CB  . LEU B 1 522 ? 150.828 143.589 110.414 1.00 43.15  ?  511 LEU B CB  1 
ATOM   9119  C CG  . LEU B 1 522 ? 150.144 143.164 111.712 1.00 43.15  ?  511 LEU B CG  1 
ATOM   9120  C CD1 . LEU B 1 522 ? 148.645 143.025 111.497 1.00 43.15  ?  511 LEU B CD1 1 
ATOM   9121  C CD2 . LEU B 1 522 ? 150.737 141.872 112.251 1.00 43.15  ?  511 LEU B CD2 1 
ATOM   9122  N N   . ALA B 1 523 ? 152.942 143.318 108.162 1.00 48.18  ?  512 ALA B N   1 
ATOM   9123  C CA  . ALA B 1 523 ? 153.408 143.618 106.822 1.00 48.18  ?  512 ALA B CA  1 
ATOM   9124  C C   . ALA B 1 523 ? 152.694 142.699 105.847 1.00 48.18  ?  512 ALA B C   1 
ATOM   9125  O O   . ALA B 1 523 ? 152.247 141.606 106.210 1.00 48.18  ?  512 ALA B O   1 
ATOM   9126  C CB  . ALA B 1 523 ? 154.924 143.456 106.697 1.00 48.18  ?  512 ALA B CB  1 
ATOM   9127  N N   . ASN B 1 524 ? 152.583 143.166 104.609 1.00 50.90  ?  513 ASN B N   1 
ATOM   9128  C CA  . ASN B 1 524 ? 151.908 142.413 103.565 1.00 50.90  ?  513 ASN B CA  1 
ATOM   9129  C C   . ASN B 1 524 ? 152.823 141.330 103.017 1.00 50.90  ?  513 ASN B C   1 
ATOM   9130  O O   . ASN B 1 524 ? 153.973 141.589 102.663 1.00 50.90  ?  513 ASN B O   1 
ATOM   9131  C CB  . ASN B 1 524 ? 151.482 143.354 102.440 1.00 50.90  ?  513 ASN B CB  1 
ATOM   9132  C CG  . ASN B 1 524 ? 150.689 142.657 101.366 1.00 50.90  ?  513 ASN B CG  1 
ATOM   9133  O OD1 . ASN B 1 524 ? 150.060 141.636 101.610 1.00 50.90  ?  513 ASN B OD1 1 
ATOM   9134  N ND2 . ASN B 1 524 ? 150.716 143.209 100.164 1.00 50.90  ?  513 ASN B ND2 1 
ATOM   9135  N N   . ILE B 1 525 ? 152.307 140.109 102.939 1.00 53.27  ?  514 ILE B N   1 
ATOM   9136  C CA  . ILE B 1 525 ? 153.052 138.985 102.388 1.00 53.27  ?  514 ILE B CA  1 
ATOM   9137  C C   . ILE B 1 525 ? 152.242 138.390 101.244 1.00 53.27  ?  514 ILE B C   1 
ATOM   9138  O O   . ILE B 1 525 ? 151.136 137.882 101.457 1.00 53.27  ?  514 ILE B O   1 
ATOM   9139  C CB  . ILE B 1 525 ? 153.379 137.922 103.446 1.00 53.27  ?  514 ILE B CB  1 
ATOM   9140  C CG1 . ILE B 1 525 ? 153.849 136.642 102.766 1.00 53.27  ?  514 ILE B CG1 1 
ATOM   9141  C CG2 . ILE B 1 525 ? 152.194 137.671 104.363 1.00 53.27  ?  514 ILE B CG2 1 
ATOM   9142  C CD1 . ILE B 1 525 ? 154.539 135.698 103.686 1.00 53.27  ?  514 ILE B CD1 1 
ATOM   9143  N N   . GLY B 1 526 ? 152.784 138.464 100.034 1.00 56.42  ?  515 GLY B N   1 
ATOM   9144  C CA  . GLY B 1 526 ? 152.168 137.865 98.872  1.00 56.42  ?  515 GLY B CA  1 
ATOM   9145  C C   . GLY B 1 526 ? 151.579 138.831 97.868  1.00 56.42  ?  515 GLY B C   1 
ATOM   9146  O O   . GLY B 1 526 ? 151.084 138.381 96.830  1.00 56.42  ?  515 GLY B O   1 
ATOM   9147  N N   . ARG B 1 527 ? 151.620 140.135 98.138  1.00 57.58  ?  516 ARG B N   1 
ATOM   9148  C CA  . ARG B 1 527 ? 151.014 141.149 97.277  1.00 57.58  ?  516 ARG B CA  1 
ATOM   9149  C C   . ARG B 1 527 ? 149.513 140.911 97.127  1.00 57.58  ?  516 ARG B C   1 
ATOM   9150  O O   . ARG B 1 527 ? 148.931 141.066 96.053  1.00 57.58  ?  516 ARG B O   1 
ATOM   9151  C CB  . ARG B 1 527 ? 151.705 141.203 95.913  1.00 57.58  ?  516 ARG B CB  1 
ATOM   9152  C CG  . ARG B 1 527 ? 153.199 141.439 95.998  1.00 57.58  ?  516 ARG B CG  1 
ATOM   9153  C CD  . ARG B 1 527 ? 153.501 142.839 96.500  1.00 57.58  ?  516 ARG B CD  1 
ATOM   9154  N NE  . ARG B 1 527 ? 154.926 143.030 96.754  1.00 57.58  ?  516 ARG B NE  1 
ATOM   9155  C CZ  . ARG B 1 527 ? 155.568 144.177 96.570  1.00 57.58  ?  516 ARG B CZ  1 
ATOM   9156  N NH1 . ARG B 1 527 ? 154.913 145.243 96.128  1.00 57.58  1  516 ARG B NH1 1 
ATOM   9157  N NH2 . ARG B 1 527 ? 156.866 144.260 96.826  1.00 57.58  ?  516 ARG B NH2 1 
ATOM   9158  N N   . THR B 1 528 ? 148.886 140.544 98.238  1.00 52.25  ?  517 THR B N   1 
ATOM   9159  C CA  . THR B 1 528 ? 147.456 140.266 98.313  1.00 52.25  ?  517 THR B CA  1 
ATOM   9160  C C   . THR B 1 528 ? 146.941 140.898 99.600  1.00 52.25  ?  517 THR B C   1 
ATOM   9161  O O   . THR B 1 528 ? 147.596 141.770 100.176 1.00 52.25  ?  517 THR B O   1 
ATOM   9162  C CB  . THR B 1 528 ? 147.185 138.752 98.245  1.00 52.25  ?  517 THR B CB  1 
ATOM   9163  O OG1 . THR B 1 528 ? 147.959 138.078 99.243  1.00 52.25  ?  517 THR B OG1 1 
ATOM   9164  C CG2 . THR B 1 528 ? 147.543 138.203 96.878  1.00 52.25  ?  517 THR B CG2 1 
ATOM   9165  N N   . ASN B 1 529 ? 145.766 140.469 100.055 1.00 47.47  ?  518 ASN B N   1 
ATOM   9166  C CA  . ASN B 1 529 ? 145.150 141.046 101.243 1.00 47.47  ?  518 ASN B CA  1 
ATOM   9167  C C   . ASN B 1 529 ? 145.508 140.300 102.523 1.00 47.47  ?  518 ASN B C   1 
ATOM   9168  O O   . ASN B 1 529 ? 144.709 140.292 103.466 1.00 47.47  ?  518 ASN B O   1 
ATOM   9169  C CB  . ASN B 1 529 ? 143.633 141.110 101.074 1.00 47.47  ?  518 ASN B CB  1 
ATOM   9170  C CG  . ASN B 1 529 ? 143.039 139.794 100.652 1.00 47.47  ?  518 ASN B CG  1 
ATOM   9171  O OD1 . ASN B 1 529 ? 143.738 138.920 100.155 1.00 47.47  ?  518 ASN B OD1 1 
ATOM   9172  N ND2 . ASN B 1 529 ? 141.739 139.643 100.845 1.00 47.47  ?  518 ASN B ND2 1 
ATOM   9173  N N   . ILE B 1 530 ? 146.683 139.685 102.589 1.00 46.92  ?  519 ILE B N   1 
ATOM   9174  C CA  . ILE B 1 530 ? 147.130 138.958 103.774 1.00 46.92  ?  519 ILE B CA  1 
ATOM   9175  C C   . ILE B 1 530 ? 148.227 139.769 104.448 1.00 46.92  ?  519 ILE B C   1 
ATOM   9176  O O   . ILE B 1 530 ? 149.254 140.068 103.832 1.00 46.92  ?  519 ILE B O   1 
ATOM   9177  C CB  . ILE B 1 530 ? 147.625 137.550 103.424 1.00 46.92  ?  519 ILE B CB  1 
ATOM   9178  C CG1 . ILE B 1 530 ? 146.662 136.872 102.460 1.00 46.92  ?  519 ILE B CG1 1 
ATOM   9179  C CG2 . ILE B 1 530 ? 147.779 136.720 104.675 1.00 46.92  ?  519 ILE B CG2 1 
ATOM   9180  C CD1 . ILE B 1 530 ? 147.165 135.572 101.937 1.00 46.92  ?  519 ILE B CD1 1 
ATOM   9181  N N   . TYR B 1 531 ? 148.011 140.114 105.716 1.00 44.17  ?  520 TYR B N   1 
ATOM   9182  C CA  . TYR B 1 531 ? 148.942 140.924 106.493 1.00 44.17  ?  520 TYR B CA  1 
ATOM   9183  C C   . TYR B 1 531 ? 149.321 140.142 107.739 1.00 44.17  ?  520 TYR B C   1 
ATOM   9184  O O   . TYR B 1 531 ? 148.469 139.875 108.591 1.00 44.17  ?  520 TYR B O   1 
ATOM   9185  C CB  . TYR B 1 531 ? 148.324 142.276 106.853 1.00 44.17  ?  520 TYR B CB  1 
ATOM   9186  C CG  . TYR B 1 531 ? 148.137 143.169 105.655 1.00 44.17  ?  520 TYR B CG  1 
ATOM   9187  C CD1 . TYR B 1 531 ? 147.050 143.015 104.818 1.00 44.17  ?  520 TYR B CD1 1 
ATOM   9188  C CD2 . TYR B 1 531 ? 149.059 144.151 105.350 1.00 44.17  ?  520 TYR B CD2 1 
ATOM   9189  C CE1 . TYR B 1 531 ? 146.883 143.814 103.719 1.00 44.17  ?  520 TYR B CE1 1 
ATOM   9190  C CE2 . TYR B 1 531 ? 148.896 144.953 104.251 1.00 44.17  ?  520 TYR B CE2 1 
ATOM   9191  C CZ  . TYR B 1 531 ? 147.806 144.778 103.440 1.00 44.17  ?  520 TYR B CZ  1 
ATOM   9192  O OH  . TYR B 1 531 ? 147.629 145.574 102.340 1.00 44.17  ?  520 TYR B OH  1 
ATOM   9193  N N   . LYS B 1 532 ? 150.591 139.780 107.849 1.00 49.08  ?  521 LYS B N   1 
ATOM   9194  C CA  . LYS B 1 532 ? 151.067 138.933 108.933 1.00 49.08  ?  521 LYS B CA  1 
ATOM   9195  C C   . LYS B 1 532 ? 152.117 139.677 109.748 1.00 49.08  ?  521 LYS B C   1 
ATOM   9196  O O   . LYS B 1 532 ? 152.449 140.823 109.465 1.00 49.08  ?  521 LYS B O   1 
ATOM   9197  C CB  . LYS B 1 532 ? 151.629 137.619 108.389 1.00 49.08  ?  521 LYS B CB  1 
ATOM   9198  C CG  . LYS B 1 532 ? 150.612 136.775 107.659 1.00 49.08  ?  521 LYS B CG  1 
ATOM   9199  C CD  . LYS B 1 532 ? 150.302 135.511 108.423 1.00 49.08  ?  521 LYS B CD  1 
ATOM   9200  C CE  . LYS B 1 532 ? 148.898 135.034 108.139 1.00 49.08  ?  521 LYS B CE  1 
ATOM   9201  N NZ  . LYS B 1 532 ? 147.900 135.785 108.940 1.00 49.08  1  521 LYS B NZ  1 
ATOM   9202  N N   . ASN B 1 533 ? 152.637 139.016 110.777 1.00 51.51  ?  522 ASN B N   1 
ATOM   9203  C CA  . ASN B 1 533 ? 153.677 139.619 111.597 1.00 51.51  ?  522 ASN B CA  1 
ATOM   9204  C C   . ASN B 1 533 ? 154.907 139.912 110.750 1.00 51.51  ?  522 ASN B C   1 
ATOM   9205  O O   . ASN B 1 533 ? 155.344 139.076 109.958 1.00 51.51  ?  522 ASN B O   1 
ATOM   9206  C CB  . ASN B 1 533 ? 154.038 138.693 112.757 1.00 51.51  ?  522 ASN B CB  1 
ATOM   9207  C CG  . ASN B 1 533 ? 154.820 139.396 113.845 1.00 51.51  ?  522 ASN B CG  1 
ATOM   9208  O OD1 . ASN B 1 533 ? 155.434 140.432 113.615 1.00 51.51  ?  522 ASN B OD1 1 
ATOM   9209  N ND2 . ASN B 1 533 ? 154.803 138.830 115.041 1.00 51.51  ?  522 ASN B ND2 1 
ATOM   9210  N N   . LYS B 1 534 ? 155.476 141.096 110.894 1.00 54.23  ?  523 LYS B N   1 
ATOM   9211  C CA  . LYS B 1 534 ? 156.610 141.492 110.062 1.00 54.23  ?  523 LYS B CA  1 
ATOM   9212  C C   . LYS B 1 534 ? 157.874 140.680 110.325 1.00 54.23  ?  523 LYS B C   1 
ATOM   9213  O O   . LYS B 1 534 ? 158.681 140.472 109.427 1.00 54.23  ?  523 LYS B O   1 
ATOM   9214  C CB  . LYS B 1 534 ? 156.876 142.981 110.276 1.00 54.23  ?  523 LYS B CB  1 
ATOM   9215  C CG  . LYS B 1 534 ? 158.112 143.521 109.587 1.00 54.23  ?  523 LYS B CG  1 
ATOM   9216  C CD  . LYS B 1 534 ? 158.354 144.965 109.990 1.00 54.23  ?  523 LYS B CD  1 
ATOM   9217  C CE  . LYS B 1 534 ? 159.586 145.529 109.306 1.00 54.23  ?  523 LYS B CE  1 
ATOM   9218  N NZ  . LYS B 1 534 ? 159.829 146.946 109.689 1.00 54.23  1  523 LYS B NZ  1 
ATOM   9219  N N   . LYS B 1 535 ? 158.041 140.210 111.549 1.00 60.50  ?  524 LYS B N   1 
ATOM   9220  C CA  . LYS B 1 535 ? 159.229 139.453 111.903 1.00 60.50  ?  524 LYS B CA  1 
ATOM   9221  C C   . LYS B 1 535 ? 159.095 137.950 111.714 1.00 60.50  ?  524 LYS B C   1 
ATOM   9222  O O   . LYS B 1 535 ? 160.032 137.218 112.013 1.00 60.50  ?  524 LYS B O   1 
ATOM   9223  C CB  . LYS B 1 535 ? 159.571 139.726 113.365 1.00 60.50  ?  524 LYS B CB  1 
ATOM   9224  C CG  . LYS B 1 535 ? 159.685 141.195 113.719 1.00 60.50  ?  524 LYS B CG  1 
ATOM   9225  C CD  . LYS B 1 535 ? 160.106 141.365 115.167 1.00 60.50  ?  524 LYS B CD  1 
ATOM   9226  C CE  . LYS B 1 535 ? 159.209 140.562 116.091 1.00 60.50  ?  524 LYS B CE  1 
ATOM   9227  N NZ  . LYS B 1 535 ? 159.638 140.670 117.513 1.00 60.50  1  524 LYS B NZ  1 
ATOM   9228  N N   . ASP B 1 536 ? 157.958 137.475 111.215 1.00 61.47  ?  525 ASP B N   1 
ATOM   9229  C CA  . ASP B 1 536 ? 157.732 136.027 111.125 1.00 61.47  ?  525 ASP B CA  1 
ATOM   9230  C C   . ASP B 1 536 ? 157.919 135.390 109.749 1.00 61.47  ?  525 ASP B C   1 
ATOM   9231  O O   . ASP B 1 536 ? 157.922 134.172 109.639 1.00 61.47  ?  525 ASP B O   1 
ATOM   9232  C CB  . ASP B 1 536 ? 156.326 135.694 111.631 1.00 61.47  ?  525 ASP B CB  1 
ATOM   9233  C CG  . ASP B 1 536 ? 156.147 135.994 113.097 1.00 61.47  ?  525 ASP B CG  1 
ATOM   9234  O OD1 . ASP B 1 536 ? 157.034 136.642 113.685 1.00 61.47  ?  525 ASP B OD1 1 
ATOM   9235  O OD2 . ASP B 1 536 ? 155.113 135.585 113.663 1.00 61.47  -1 525 ASP B OD2 1 
ATOM   9236  N N   . TYR B 1 537 ? 158.068 136.191 108.706 1.00 59.74  ?  526 TYR B N   1 
ATOM   9237  C CA  . TYR B 1 537 ? 158.169 135.632 107.365 1.00 59.74  ?  526 TYR B CA  1 
ATOM   9238  C C   . TYR B 1 537 ? 159.193 136.354 106.524 1.00 59.74  ?  526 TYR B C   1 
ATOM   9239  O O   . TYR B 1 537 ? 159.678 137.415 106.902 1.00 59.74  ?  526 TYR B O   1 
ATOM   9240  C CB  . TYR B 1 537 ? 156.822 135.693 106.645 1.00 59.74  ?  526 TYR B CB  1 
ATOM   9241  C CG  . TYR B 1 537 ? 155.714 134.904 107.290 1.00 59.74  ?  526 TYR B CG  1 
ATOM   9242  C CD1 . TYR B 1 537 ? 155.492 133.580 106.947 1.00 59.74  ?  526 TYR B CD1 1 
ATOM   9243  C CD2 . TYR B 1 537 ? 154.880 135.487 108.232 1.00 59.74  ?  526 TYR B CD2 1 
ATOM   9244  C CE1 . TYR B 1 537 ? 154.474 132.854 107.530 1.00 59.74  ?  526 TYR B CE1 1 
ATOM   9245  C CE2 . TYR B 1 537 ? 153.862 134.768 108.821 1.00 59.74  ?  526 TYR B CE2 1 
ATOM   9246  C CZ  . TYR B 1 537 ? 153.663 133.452 108.465 1.00 59.74  ?  526 TYR B CZ  1 
ATOM   9247  O OH  . TYR B 1 537 ? 152.650 132.730 109.047 1.00 59.74  ?  526 TYR B OH  1 
ATOM   9248  N N   . TYR B 1 538 ? 159.521 135.785 105.375 1.00 66.85  ?  527 TYR B N   1 
ATOM   9249  C CA  . TYR B 1 538 ? 160.469 136.418 104.476 1.00 66.85  ?  527 TYR B CA  1 
ATOM   9250  C C   . TYR B 1 538 ? 159.734 137.100 103.342 1.00 66.85  ?  527 TYR B C   1 
ATOM   9251  O O   . TYR B 1 538 ? 158.590 136.765 103.056 1.00 66.85  ?  527 TYR B O   1 
ATOM   9252  C CB  . TYR B 1 538 ? 161.440 135.386 103.901 1.00 66.85  ?  527 TYR B CB  1 
ATOM   9253  C CG  . TYR B 1 538 ? 162.235 134.619 104.927 1.00 66.85  ?  527 TYR B CG  1 
ATOM   9254  C CD1 . TYR B 1 538 ? 163.369 135.167 105.506 1.00 66.85  ?  527 TYR B CD1 1 
ATOM   9255  C CD2 . TYR B 1 538 ? 161.864 133.336 105.302 1.00 66.85  ?  527 TYR B CD2 1 
ATOM   9256  C CE1 . TYR B 1 538 ? 164.104 134.465 106.440 1.00 66.85  ?  527 TYR B CE1 1 
ATOM   9257  C CE2 . TYR B 1 538 ? 162.593 132.625 106.233 1.00 66.85  ?  527 TYR B CE2 1 
ATOM   9258  C CZ  . TYR B 1 538 ? 163.711 133.195 106.799 1.00 66.85  ?  527 TYR B CZ  1 
ATOM   9259  O OH  . TYR B 1 538 ? 164.442 132.493 107.727 1.00 66.85  ?  527 TYR B OH  1 
ATOM   9260  N N   . ASP B 1 539 ? 160.379 138.064 102.700 1.00 65.22  ?  528 ASP B N   1 
ATOM   9261  C CA  . ASP B 1 539 ? 159.780 138.741 101.553 1.00 65.22  ?  528 ASP B CA  1 
ATOM   9262  C C   . ASP B 1 539 ? 158.481 139.455 101.897 1.00 65.22  ?  528 ASP B C   1 
ATOM   9263  O O   . ASP B 1 539 ? 157.553 139.487 101.094 1.00 65.22  ?  528 ASP B O   1 
ATOM   9264  C CB  . ASP B 1 539 ? 159.551 137.741 100.417 1.00 65.22  ?  528 ASP B CB  1 
ATOM   9265  C CG  . ASP B 1 539 ? 160.794 136.944 100.081 1.00 65.22  ?  528 ASP B CG  1 
ATOM   9266  O OD1 . ASP B 1 539 ? 161.875 137.269 100.614 1.00 65.22  ?  528 ASP B OD1 1 
ATOM   9267  O OD2 . ASP B 1 539 ? 160.689 135.990 99.283  1.00 65.22  -1 528 ASP B OD2 1 
ATOM   9268  N N   . MET B 1 540 ? 158.414 140.033 103.087 1.00 57.28  ?  529 MET B N   1 
ATOM   9269  C CA  . MET B 1 540 ? 157.228 140.758 103.489 1.00 57.28  ?  529 MET B CA  1 
ATOM   9270  C C   . MET B 1 540 ? 157.347 142.184 103.002 1.00 57.28  ?  529 MET B C   1 
ATOM   9271  O O   . MET B 1 540 ? 158.445 142.665 102.759 1.00 57.28  ?  529 MET B O   1 
ATOM   9272  C CB  . MET B 1 540 ? 157.065 140.692 104.999 1.00 57.28  ?  529 MET B CB  1 
ATOM   9273  C CG  . MET B 1 540 ? 157.122 139.275 105.538 1.00 57.28  ?  529 MET B CG  1 
ATOM   9274  S SD  . MET B 1 540 ? 156.458 139.140 107.203 1.00 57.28  ?  529 MET B SD  1 
ATOM   9275  C CE  . MET B 1 540 ? 154.721 139.434 106.887 1.00 57.28  ?  529 MET B CE  1 
ATOM   9276  N N   . TYR B 1 541 ? 156.229 142.877 102.860 1.00 55.95  ?  530 TYR B N   1 
ATOM   9277  C CA  . TYR B 1 541 ? 156.262 144.228 102.323 1.00 55.95  ?  530 TYR B CA  1 
ATOM   9278  C C   . TYR B 1 541 ? 155.498 145.226 103.158 1.00 55.95  ?  530 TYR B C   1 
ATOM   9279  O O   . TYR B 1 541 ? 154.356 144.991 103.524 1.00 55.95  ?  530 TYR B O   1 
ATOM   9280  C CB  . TYR B 1 541 ? 155.706 144.228 100.902 1.00 55.95  ?  530 TYR B CB  1 
ATOM   9281  C CG  . TYR B 1 541 ? 155.334 145.588 100.368 1.00 55.95  ?  530 TYR B CG  1 
ATOM   9282  C CD1 . TYR B 1 541 ? 154.007 145.979 100.285 1.00 55.95  ?  530 TYR B CD1 1 
ATOM   9283  C CD2 . TYR B 1 541 ? 156.308 146.477 99.941  1.00 55.95  ?  530 TYR B CD2 1 
ATOM   9284  C CE1 . TYR B 1 541 ? 153.659 147.219 99.794  1.00 55.95  ?  530 TYR B CE1 1 
ATOM   9285  C CE2 . TYR B 1 541 ? 155.969 147.720 99.447  1.00 55.95  ?  530 TYR B CE2 1 
ATOM   9286  C CZ  . TYR B 1 541 ? 154.643 148.086 99.377  1.00 55.95  ?  530 TYR B CZ  1 
ATOM   9287  O OH  . TYR B 1 541 ? 154.299 149.323 98.888  1.00 55.95  ?  530 TYR B OH  1 
ATOM   9288  N N   . GLU B 1 542 ? 156.135 146.339 103.478 1.00 54.15  ?  531 GLU B N   1 
ATOM   9289  C CA  . GLU B 1 542 ? 155.444 147.395 104.196 1.00 54.15  ?  531 GLU B CA  1 
ATOM   9290  C C   . GLU B 1 542 ? 155.305 148.583 103.269 1.00 54.15  ?  531 GLU B C   1 
ATOM   9291  O O   . GLU B 1 542 ? 156.299 149.150 102.830 1.00 54.15  ?  531 GLU B O   1 
ATOM   9292  C CB  . GLU B 1 542 ? 156.197 147.778 105.464 1.00 54.15  ?  531 GLU B CB  1 
ATOM   9293  C CG  . GLU B 1 542 ? 155.867 146.923 106.671 1.00 54.15  ?  531 GLU B CG  1 
ATOM   9294  C CD  . GLU B 1 542 ? 156.595 147.380 107.917 1.00 54.15  ?  531 GLU B CD  1 
ATOM   9295  O OE1 . GLU B 1 542 ? 156.057 147.192 109.027 1.00 54.15  ?  531 GLU B OE1 1 
ATOM   9296  O OE2 . GLU B 1 542 ? 157.700 147.942 107.789 1.00 54.15  -1 531 GLU B OE2 1 
ATOM   9297  N N   . PRO B 1 543 ? 154.063 148.959 102.957 1.00 55.00  ?  532 PRO B N   1 
ATOM   9298  C CA  . PRO B 1 543 ? 153.846 150.126 102.103 1.00 55.00  ?  532 PRO B CA  1 
ATOM   9299  C C   . PRO B 1 543 ? 154.570 151.324 102.684 1.00 55.00  ?  532 PRO B C   1 
ATOM   9300  O O   . PRO B 1 543 ? 154.557 151.509 103.897 1.00 55.00  ?  532 PRO B O   1 
ATOM   9301  C CB  . PRO B 1 543 ? 152.334 150.321 102.160 1.00 55.00  ?  532 PRO B CB  1 
ATOM   9302  C CG  . PRO B 1 543 ? 151.789 148.971 102.468 1.00 55.00  ?  532 PRO B CG  1 
ATOM   9303  C CD  . PRO B 1 543 ? 152.803 148.313 103.355 1.00 55.00  ?  532 PRO B CD  1 
ATOM   9304  N N   . GLU B 1 544 ? 155.207 152.122 101.842 1.00 58.04  ?  533 GLU B N   1 
ATOM   9305  C CA  . GLU B 1 544 ? 155.989 153.253 102.326 1.00 58.04  ?  533 GLU B CA  1 
ATOM   9306  C C   . GLU B 1 544 ? 155.165 154.251 103.116 1.00 58.04  ?  533 GLU B C   1 
ATOM   9307  O O   . GLU B 1 544 ? 154.082 154.642 102.694 1.00 58.04  ?  533 GLU B O   1 
ATOM   9308  C CB  . GLU B 1 544 ? 156.667 153.962 101.155 1.00 58.04  ?  533 GLU B CB  1 
ATOM   9309  C CG  . GLU B 1 544 ? 157.500 155.169 101.554 1.00 58.04  ?  533 GLU B CG  1 
ATOM   9310  C CD  . GLU B 1 544 ? 158.170 155.833 100.368 1.00 58.04  ?  533 GLU B CD  1 
ATOM   9311  O OE1 . GLU B 1 544 ? 158.073 155.291 99.248  1.00 58.04  ?  533 GLU B OE1 1 
ATOM   9312  O OE2 . GLU B 1 544 ? 158.798 156.896 100.555 1.00 58.04  -1 533 GLU B OE2 1 
ATOM   9313  N N   . GLY B 1 545 ? 155.680 154.665 104.263 1.00 51.45  ?  534 GLY B N   1 
ATOM   9314  C CA  . GLY B 1 545 ? 154.980 155.625 105.085 1.00 51.45  ?  534 GLY B CA  1 
ATOM   9315  C C   . GLY B 1 545 ? 153.868 155.010 105.890 1.00 51.45  ?  534 GLY B C   1 
ATOM   9316  O O   . GLY B 1 545 ? 153.220 155.701 106.664 1.00 51.45  ?  534 GLY B O   1 
ATOM   9317  N N   . VAL B 1 546 ? 153.628 153.713 105.713 1.00 48.61  ?  535 VAL B N   1 
ATOM   9318  C CA  . VAL B 1 546 ? 152.506 153.107 106.406 1.00 48.61  ?  535 VAL B CA  1 
ATOM   9319  C C   . VAL B 1 546 ? 152.967 152.138 107.485 1.00 48.61  ?  535 VAL B C   1 
ATOM   9320  O O   . VAL B 1 546 ? 153.916 151.397 107.294 1.00 48.61  ?  535 VAL B O   1 
ATOM   9321  C CB  . VAL B 1 546 ? 151.607 152.352 105.409 1.00 48.61  ?  535 VAL B CB  1 
ATOM   9322  C CG1 . VAL B 1 546 ? 150.364 151.810 106.079 1.00 48.61  ?  535 VAL B CG1 1 
ATOM   9323  C CG2 . VAL B 1 546 ? 151.211 153.248 104.257 1.00 48.61  ?  535 VAL B CG2 1 
ATOM   9324  N N   . LYS B 1 547 ? 152.318 152.191 108.639 1.00 45.64  ?  536 LYS B N   1 
ATOM   9325  C CA  . LYS B 1 547 ? 152.594 151.280 109.737 1.00 45.64  ?  536 LYS B CA  1 
ATOM   9326  C C   . LYS B 1 547 ? 151.295 150.600 110.134 1.00 45.64  ?  536 LYS B C   1 
ATOM   9327  O O   . LYS B 1 547 ? 150.277 151.269 110.321 1.00 45.64  ?  536 LYS B O   1 
ATOM   9328  C CB  . LYS B 1 547 ? 153.187 152.015 110.941 1.00 45.64  ?  536 LYS B CB  1 
ATOM   9329  C CG  . LYS B 1 547 ? 154.681 152.245 110.873 1.00 45.64  ?  536 LYS B CG  1 
ATOM   9330  C CD  . LYS B 1 547 ? 155.454 151.022 111.300 1.00 45.64  ?  536 LYS B CD  1 
ATOM   9331  C CE  . LYS B 1 547 ? 156.906 151.138 110.895 1.00 45.64  ?  536 LYS B CE  1 
ATOM   9332  N NZ  . LYS B 1 547 ? 157.610 149.837 111.019 1.00 45.64  1  536 LYS B NZ  1 
ATOM   9333  N N   . ILE B 1 548 ? 151.332 149.281 110.261 1.00 40.94  ?  537 ILE B N   1 
ATOM   9334  C CA  . ILE B 1 548 ? 150.186 148.500 110.703 1.00 40.94  ?  537 ILE B CA  1 
ATOM   9335  C C   . ILE B 1 548 ? 150.553 147.894 112.047 1.00 40.94  ?  537 ILE B C   1 
ATOM   9336  O O   . ILE B 1 548 ? 151.530 147.149 112.154 1.00 40.94  ?  537 ILE B O   1 
ATOM   9337  C CB  . ILE B 1 548 ? 149.800 147.421 109.685 1.00 40.94  ?  537 ILE B CB  1 
ATOM   9338  C CG1 . ILE B 1 548 ? 149.713 148.019 108.286 1.00 40.94  ?  537 ILE B CG1 1 
ATOM   9339  C CG2 . ILE B 1 548 ? 148.481 146.797 110.058 1.00 40.94  ?  537 ILE B CG2 1 
ATOM   9340  C CD1 . ILE B 1 548 ? 149.947 147.036 107.193 1.00 40.94  ?  537 ILE B CD1 1 
ATOM   9341  N N   . PHE B 1 549 ? 149.776 148.207 113.074 1.00 40.13  ?  538 PHE B N   1 
ATOM   9342  C CA  . PHE B 1 549 ? 150.071 147.805 114.440 1.00 40.13  ?  538 PHE B CA  1 
ATOM   9343  C C   . PHE B 1 549 ? 148.907 146.994 114.989 1.00 40.13  ?  538 PHE B C   1 
ATOM   9344  O O   . PHE B 1 549 ? 147.747 147.375 114.816 1.00 40.13  ?  538 PHE B O   1 
ATOM   9345  C CB  . PHE B 1 549 ? 150.332 149.034 115.312 1.00 40.13  ?  538 PHE B CB  1 
ATOM   9346  C CG  . PHE B 1 549 ? 150.720 148.713 116.723 1.00 40.13  ?  538 PHE B CG  1 
ATOM   9347  C CD1 . PHE B 1 549 ? 151.956 148.180 117.011 1.00 40.13  ?  538 PHE B CD1 1 
ATOM   9348  C CD2 . PHE B 1 549 ? 149.846 148.955 117.763 1.00 40.13  ?  538 PHE B CD2 1 
ATOM   9349  C CE1 . PHE B 1 549 ? 152.305 147.891 118.299 1.00 40.13  ?  538 PHE B CE1 1 
ATOM   9350  C CE2 . PHE B 1 549 ? 150.196 148.664 119.053 1.00 40.13  ?  538 PHE B CE2 1 
ATOM   9351  C CZ  . PHE B 1 549 ? 151.425 148.141 119.319 1.00 40.13  ?  538 PHE B CZ  1 
ATOM   9352  N N   . ARG B 1 550 ? 149.216 145.882 115.648 1.00 42.93  ?  539 ARG B N   1 
ATOM   9353  C CA  . ARG B 1 550 ? 148.204 144.969 116.156 1.00 42.93  ?  539 ARG B CA  1 
ATOM   9354  C C   . ARG B 1 550 ? 148.433 144.726 117.640 1.00 42.93  ?  539 ARG B C   1 
ATOM   9355  O O   . ARG B 1 550 ? 149.517 144.304 118.042 1.00 42.93  ?  539 ARG B O   1 
ATOM   9356  C CB  . ARG B 1 550 ? 148.239 143.651 115.386 1.00 42.93  ?  539 ARG B CB  1 
ATOM   9357  C CG  . ARG B 1 550 ? 147.336 142.593 115.959 1.00 42.93  ?  539 ARG B CG  1 
ATOM   9358  C CD  . ARG B 1 550 ? 147.492 141.280 115.237 1.00 42.93  ?  539 ARG B CD  1 
ATOM   9359  N NE  . ARG B 1 550 ? 146.921 140.186 116.009 1.00 42.93  ?  539 ARG B NE  1 
ATOM   9360  C CZ  . ARG B 1 550 ? 145.647 139.820 115.953 1.00 42.93  ?  539 ARG B CZ  1 
ATOM   9361  N NH1 . ARG B 1 550 ? 145.215 138.812 116.691 1.00 42.93  1  539 ARG B NH1 1 
ATOM   9362  N NH2 . ARG B 1 550 ? 144.807 140.459 115.157 1.00 42.93  ?  539 ARG B NH2 1 
ATOM   9363  N N   . CYS B 1 551 ? 147.417 145.016 118.449 1.00 45.22  ?  540 CYS B N   1 
ATOM   9364  C CA  . CYS B 1 551 ? 147.374 144.589 119.840 1.00 45.22  ?  540 CYS B CA  1 
ATOM   9365  C C   . CYS B 1 551 ? 146.376 143.449 119.956 1.00 45.22  ?  540 CYS B C   1 
ATOM   9366  O O   . CYS B 1 551 ? 145.182 143.657 119.697 1.00 45.22  ?  540 CYS B O   1 
ATOM   9367  C CB  . CYS B 1 551 ? 146.982 145.739 120.763 1.00 45.22  ?  540 CYS B CB  1 
ATOM   9368  S SG  . CYS B 1 551 ? 146.945 145.308 122.518 1.00 45.22  ?  540 CYS B SG  1 
ATOM   9369  N N   . PRO B 1 552 ? 146.864 142.240 120.251 1.00 43.52  ?  541 PRO B N   1 
ATOM   9370  C CA  . PRO B 1 552 ? 146.090 141.001 120.288 1.00 43.52  ?  541 PRO B CA  1 
ATOM   9371  C C   . PRO B 1 552 ? 145.233 140.717 121.500 1.00 43.52  ?  541 PRO B C   1 
ATOM   9372  O O   . PRO B 1 552 ? 145.139 139.556 121.872 1.00 43.52  ?  541 PRO B O   1 
ATOM   9373  C CB  . PRO B 1 552 ? 147.170 139.937 120.176 1.00 43.52  ?  541 PRO B CB  1 
ATOM   9374  C CG  . PRO B 1 552 ? 148.343 140.544 120.841 1.00 43.52  ?  541 PRO B CG  1 
ATOM   9375  C CD  . PRO B 1 552 ? 148.275 142.013 120.585 1.00 43.52  ?  541 PRO B CD  1 
ATOM   9376  N N   . SER B 1 553 ? 144.732 141.765 122.155 1.00 41.12  ?  542 SER B N   1 
ATOM   9377  C CA  . SER B 1 553 ? 143.967 141.611 123.383 1.00 41.12  ?  542 SER B CA  1 
ATOM   9378  C C   . SER B 1 553 ? 143.056 142.786 123.650 1.00 41.12  ?  542 SER B C   1 
ATOM   9379  O O   . SER B 1 553 ? 143.194 143.829 123.024 1.00 41.12  ?  542 SER B O   1 
ATOM   9380  C CB  . SER B 1 553 ? 144.923 141.500 124.571 1.00 41.12  ?  542 SER B CB  1 
ATOM   9381  O OG  . SER B 1 553 ? 145.449 142.762 124.936 1.00 41.12  ?  542 SER B OG  1 
ATOM   9382  N N   . PRO B 1 554 ? 142.115 142.628 124.590 1.00 41.12  ?  543 PRO B N   1 
ATOM   9383  C CA  . PRO B 1 554 ? 141.305 143.789 124.967 1.00 41.12  ?  543 PRO B CA  1 
ATOM   9384  C C   . PRO B 1 554 ? 142.191 144.856 125.597 1.00 41.12  ?  543 PRO B C   1 
ATOM   9385  O O   . PRO B 1 554 ? 143.139 144.524 126.291 1.00 41.12  ?  543 PRO B O   1 
ATOM   9386  C CB  . PRO B 1 554 ? 140.359 143.227 126.026 1.00 41.12  ?  543 PRO B CB  1 
ATOM   9387  C CG  . PRO B 1 554 ? 140.328 141.758 125.779 1.00 41.12  ?  543 PRO B CG  1 
ATOM   9388  C CD  . PRO B 1 554 ? 141.696 141.405 125.290 1.00 41.12  ?  543 PRO B CD  1 
ATOM   9389  N N   . ILE B 1 555 ? 141.885 146.119 125.366 1.00 41.38  ?  544 ILE B N   1 
ATOM   9390  C CA  . ILE B 1 555 ? 142.676 147.189 125.940 1.00 41.38  ?  544 ILE B CA  1 
ATOM   9391  C C   . ILE B 1 555 ? 141.883 147.836 127.044 1.00 41.38  ?  544 ILE B C   1 
ATOM   9392  O O   . ILE B 1 555 ? 140.737 148.217 126.842 1.00 41.38  ?  544 ILE B O   1 
ATOM   9393  C CB  . ILE B 1 555 ? 143.101 148.223 124.885 1.00 41.38  ?  544 ILE B CB  1 
ATOM   9394  C CG1 . ILE B 1 555 ? 143.752 147.517 123.694 1.00 41.38  ?  544 ILE B CG1 1 
ATOM   9395  C CG2 . ILE B 1 555 ? 144.048 149.244 125.495 1.00 41.38  ?  544 ILE B CG2 1 
ATOM   9396  C CD1 . ILE B 1 555 ? 144.162 148.449 122.578 1.00 41.38  ?  544 ILE B CD1 1 
ATOM   9397  N N   . TYR B 1 556 ? 142.482 147.934 128.221 1.00 37.93  ?  545 TYR B N   1 
ATOM   9398  C CA  . TYR B 1 556 ? 141.796 148.510 129.368 1.00 37.93  ?  545 TYR B CA  1 
ATOM   9399  C C   . TYR B 1 556 ? 142.788 149.154 130.327 1.00 37.93  ?  545 TYR B C   1 
ATOM   9400  O O   . TYR B 1 556 ? 143.922 149.401 129.954 1.00 37.93  ?  545 TYR B O   1 
ATOM   9401  C CB  . TYR B 1 556 ? 140.942 147.451 130.077 1.00 37.93  ?  545 TYR B CB  1 
ATOM   9402  C CG  . TYR B 1 556 ? 141.710 146.256 130.583 1.00 37.93  ?  545 TYR B CG  1 
ATOM   9403  C CD1 . TYR B 1 556 ? 142.223 145.312 129.706 1.00 37.93  ?  545 TYR B CD1 1 
ATOM   9404  C CD2 . TYR B 1 556 ? 141.910 146.065 131.942 1.00 37.93  ?  545 TYR B CD2 1 
ATOM   9405  C CE1 . TYR B 1 556 ? 142.926 144.218 130.167 1.00 37.93  ?  545 TYR B CE1 1 
ATOM   9406  C CE2 . TYR B 1 556 ? 142.608 144.972 132.413 1.00 37.93  ?  545 TYR B CE2 1 
ATOM   9407  C CZ  . TYR B 1 556 ? 143.113 144.052 131.522 1.00 37.93  ?  545 TYR B CZ  1 
ATOM   9408  O OH  . TYR B 1 556 ? 143.810 142.963 131.987 1.00 37.93  ?  545 TYR B OH  1 
ATOM   9409  N N   . PHE B 1 557 ? 142.375 149.416 131.557 1.00 39.05  ?  546 PHE B N   1 
ATOM   9410  C CA  . PHE B 1 557 ? 143.232 150.116 132.521 1.00 39.05  ?  546 PHE B CA  1 
ATOM   9411  C C   . PHE B 1 557 ? 144.579 149.462 132.810 1.00 39.05  ?  546 PHE B C   1 
ATOM   9412  O O   . PHE B 1 557 ? 145.562 150.157 133.031 1.00 39.05  ?  546 PHE B O   1 
ATOM   9413  C CB  . PHE B 1 557 ? 142.473 150.331 133.842 1.00 39.05  ?  546 PHE B CB  1 
ATOM   9414  C CG  . PHE B 1 557 ? 142.170 149.069 134.595 1.00 39.05  ?  546 PHE B CG  1 
ATOM   9415  C CD1 . PHE B 1 557 ? 140.974 148.404 134.398 1.00 39.05  ?  546 PHE B CD1 1 
ATOM   9416  C CD2 . PHE B 1 557 ? 143.068 148.564 135.520 1.00 39.05  ?  546 PHE B CD2 1 
ATOM   9417  C CE1 . PHE B 1 557 ? 140.685 147.248 135.093 1.00 39.05  ?  546 PHE B CE1 1 
ATOM   9418  C CE2 . PHE B 1 557 ? 142.786 147.407 136.218 1.00 39.05  ?  546 PHE B CE2 1 
ATOM   9419  C CZ  . PHE B 1 557 ? 141.592 146.749 136.004 1.00 39.05  ?  546 PHE B CZ  1 
ATOM   9420  N N   . ALA B 1 558 ? 144.638 148.139 132.804 1.00 38.04  ?  547 ALA B N   1 
ATOM   9421  C CA  . ALA B 1 558 ? 145.876 147.452 133.155 1.00 38.04  ?  547 ALA B CA  1 
ATOM   9422  C C   . ALA B 1 558 ? 146.917 147.345 132.031 1.00 38.04  ?  547 ALA B C   1 
ATOM   9423  O O   . ALA B 1 558 ? 148.064 147.015 132.299 1.00 38.04  ?  547 ALA B O   1 
ATOM   9424  C CB  . ALA B 1 558 ? 145.549 146.075 133.703 1.00 38.04  ?  547 ALA B CB  1 
ATOM   9425  N N   . ASN B 1 559 ? 146.536 147.626 130.792 1.00 39.83  ?  548 ASN B N   1 
ATOM   9426  C CA  . ASN B 1 559 ? 147.472 147.490 129.676 1.00 39.83  ?  548 ASN B CA  1 
ATOM   9427  C C   . ASN B 1 559 ? 147.507 148.700 128.746 1.00 39.83  ?  548 ASN B C   1 
ATOM   9428  O O   . ASN B 1 559 ? 148.216 148.686 127.751 1.00 39.83  ?  548 ASN B O   1 
ATOM   9429  C CB  . ASN B 1 559 ? 147.175 146.211 128.875 1.00 39.83  ?  548 ASN B CB  1 
ATOM   9430  C CG  . ASN B 1 559 ? 145.778 146.180 128.298 1.00 39.83  ?  548 ASN B CG  1 
ATOM   9431  O OD1 . ASN B 1 559 ? 145.024 147.140 128.400 1.00 39.83  ?  548 ASN B OD1 1 
ATOM   9432  N ND2 . ASN B 1 559 ? 145.428 145.061 127.685 1.00 39.83  ?  548 ASN B ND2 1 
ATOM   9433  N N   . ILE B 1 560 ? 146.745 149.738 129.059 1.00 41.41  ?  549 ILE B N   1 
ATOM   9434  C CA  . ILE B 1 560 ? 146.691 150.912 128.191 1.00 41.41  ?  549 ILE B CA  1 
ATOM   9435  C C   . ILE B 1 560 ? 148.051 151.603 128.085 1.00 41.41  ?  549 ILE B C   1 
ATOM   9436  O O   . ILE B 1 560 ? 148.444 152.014 127.002 1.00 41.41  ?  549 ILE B O   1 
ATOM   9437  C CB  . ILE B 1 560 ? 145.592 151.910 128.638 1.00 41.41  ?  549 ILE B CB  1 
ATOM   9438  C CG1 . ILE B 1 560 ? 145.544 153.121 127.700 1.00 41.41  ?  549 ILE B CG1 1 
ATOM   9439  C CG2 . ILE B 1 560 ? 145.804 152.348 130.079 1.00 41.41  ?  549 ILE B CG2 1 
ATOM   9440  C CD1 . ILE B 1 560 ? 145.202 152.781 126.267 1.00 41.41  ?  549 ILE B CD1 1 
ATOM   9441  N N   . GLY B 1 561 ? 148.768 151.734 129.195 1.00 41.75  ?  550 GLY B N   1 
ATOM   9442  C CA  . GLY B 1 561 ? 150.096 152.316 129.167 1.00 41.75  ?  550 GLY B CA  1 
ATOM   9443  C C   . GLY B 1 561 ? 151.056 151.486 128.356 1.00 41.75  ?  550 GLY B C   1 
ATOM   9444  O O   . GLY B 1 561 ? 151.894 152.030 127.653 1.00 41.75  ?  550 GLY B O   1 
ATOM   9445  N N   . PHE B 1 562 ? 150.938 150.173 128.453 1.00 39.77  ?  551 PHE B N   1 
ATOM   9446  C CA  . PHE B 1 562 ? 151.782 149.274 127.685 1.00 39.77  ?  551 PHE B CA  1 
ATOM   9447  C C   . PHE B 1 562 ? 151.492 149.409 126.196 1.00 39.77  ?  551 PHE B C   1 
ATOM   9448  O O   . PHE B 1 562 ? 152.408 149.345 125.388 1.00 39.77  ?  551 PHE B O   1 
ATOM   9449  C CB  . PHE B 1 562 ? 151.564 147.839 128.173 1.00 39.77  ?  551 PHE B CB  1 
ATOM   9450  C CG  . PHE B 1 562 ? 152.517 146.838 127.596 1.00 39.77  ?  551 PHE B CG  1 
ATOM   9451  C CD1 . PHE B 1 562 ? 152.174 146.102 126.479 1.00 39.77  ?  551 PHE B CD1 1 
ATOM   9452  C CD2 . PHE B 1 562 ? 153.745 146.613 128.190 1.00 39.77  ?  551 PHE B CD2 1 
ATOM   9453  C CE1 . PHE B 1 562 ? 153.045 145.174 125.952 1.00 39.77  ?  551 PHE B CE1 1 
ATOM   9454  C CE2 . PHE B 1 562 ? 154.623 145.685 127.669 1.00 39.77  ?  551 PHE B CE2 1 
ATOM   9455  C CZ  . PHE B 1 562 ? 154.271 144.963 126.549 1.00 39.77  ?  551 PHE B CZ  1 
ATOM   9456  N N   . PHE B 1 563 ? 150.230 149.619 125.831 1.00 40.13  ?  552 PHE B N   1 
ATOM   9457  C CA  . PHE B 1 563 ? 149.850 149.796 124.434 1.00 40.13  ?  552 PHE B CA  1 
ATOM   9458  C C   . PHE B 1 563 ? 150.483 151.048 123.843 1.00 40.13  ?  552 PHE B C   1 
ATOM   9459  O O   . PHE B 1 563 ? 150.974 151.023 122.711 1.00 40.13  ?  552 PHE B O   1 
ATOM   9460  C CB  . PHE B 1 563 ? 148.328 149.847 124.313 1.00 40.13  ?  552 PHE B CB  1 
ATOM   9461  C CG  . PHE B 1 563 ? 147.837 150.214 122.942 1.00 40.13  ?  552 PHE B CG  1 
ATOM   9462  C CD1 . PHE B 1 563 ? 147.383 151.488 122.672 1.00 40.13  ?  552 PHE B CD1 1 
ATOM   9463  C CD2 . PHE B 1 563 ? 147.824 149.282 121.927 1.00 40.13  ?  552 PHE B CD2 1 
ATOM   9464  C CE1 . PHE B 1 563 ? 146.940 151.824 121.419 1.00 40.13  ?  552 PHE B CE1 1 
ATOM   9465  C CE2 . PHE B 1 563 ? 147.378 149.615 120.675 1.00 40.13  ?  552 PHE B CE2 1 
ATOM   9466  C CZ  . PHE B 1 563 ? 146.938 150.889 120.422 1.00 40.13  ?  552 PHE B CZ  1 
ATOM   9467  N N   . ARG B 1 564 ? 150.505 152.103 124.641 1.00 43.81  ?  553 ARG B N   1 
ATOM   9468  C CA  . ARG B 1 564 ? 151.078 153.358 124.249 1.00 43.81  ?  553 ARG B CA  1 
ATOM   9469  C C   . ARG B 1 564 ? 152.586 153.264 124.066 1.00 43.81  ?  553 ARG B C   1 
ATOM   9470  O O   . ARG B 1 564 ? 153.102 153.809 123.129 1.00 43.81  ?  553 ARG B O   1 
ATOM   9471  C CB  . ARG B 1 564 ? 150.705 154.445 125.245 1.00 43.81  ?  553 ARG B CB  1 
ATOM   9472  C CG  . ARG B 1 564 ? 151.043 155.835 124.760 1.00 43.81  ?  553 ARG B CG  1 
ATOM   9473  C CD  . ARG B 1 564 ? 151.004 156.867 125.859 1.00 43.81  ?  553 ARG B CD  1 
ATOM   9474  N NE  . ARG B 1 564 ? 150.583 158.152 125.328 1.00 43.81  ?  553 ARG B NE  1 
ATOM   9475  C CZ  . ARG B 1 564 ? 149.325 158.577 125.328 1.00 43.81  ?  553 ARG B CZ  1 
ATOM   9476  N NH1 . ARG B 1 564 ? 149.038 159.754 124.811 1.00 43.81  1  553 ARG B NH1 1 
ATOM   9477  N NH2 . ARG B 1 564 ? 148.358 157.829 125.854 1.00 43.81  ?  553 ARG B NH2 1 
ATOM   9478  N N   . ARG B 1 565 ? 153.274 152.592 124.982 1.00 42.48  ?  554 ARG B N   1 
ATOM   9479  C CA  . ARG B 1 565 ? 154.715 152.366 124.900 1.00 42.48  ?  554 ARG B CA  1 
ATOM   9480  C C   . ARG B 1 565 ? 155.071 151.534 123.679 1.00 42.48  ?  554 ARG B C   1 
ATOM   9481  O O   . ARG B 1 565 ? 156.019 151.856 122.955 1.00 42.48  ?  554 ARG B O   1 
ATOM   9482  C CB  . ARG B 1 565 ? 155.217 151.681 126.168 1.00 42.48  ?  554 ARG B CB  1 
ATOM   9483  C CG  . ARG B 1 565 ? 155.198 152.559 127.395 1.00 42.48  ?  554 ARG B CG  1 
ATOM   9484  C CD  . ARG B 1 565 ? 155.986 151.930 128.524 1.00 42.48  ?  554 ARG B CD  1 
ATOM   9485  N NE  . ARG B 1 565 ? 155.129 151.552 129.642 1.00 42.48  ?  554 ARG B NE  1 
ATOM   9486  C CZ  . ARG B 1 565 ? 154.929 150.300 130.034 1.00 42.48  ?  554 ARG B CZ  1 
ATOM   9487  N NH1 . ARG B 1 565 ? 154.134 150.043 131.062 1.00 42.48  1  554 ARG B NH1 1 
ATOM   9488  N NH2 . ARG B 1 565 ? 155.531 149.305 129.399 1.00 42.48  ?  554 ARG B NH2 1 
ATOM   9489  N N   . LYS B 1 566 ? 154.308 150.470 123.418 1.00 42.12  ?  555 LYS B N   1 
ATOM   9490  C CA  . LYS B 1 566 ? 154.617 149.602 122.291 1.00 42.12  ?  555 LYS B CA  1 
ATOM   9491  C C   . LYS B 1 566 ? 154.307 150.278 120.963 1.00 42.12  ?  555 LYS B C   1 
ATOM   9492  O O   . LYS B 1 566 ? 155.042 150.094 119.989 1.00 42.12  ?  555 LYS B O   1 
ATOM   9493  C CB  . LYS B 1 566 ? 153.856 148.291 122.425 1.00 42.12  ?  555 LYS B CB  1 
ATOM   9494  C CG  . LYS B 1 566 ? 154.287 147.482 123.616 1.00 42.12  ?  555 LYS B CG  1 
ATOM   9495  C CD  . LYS B 1 566 ? 155.668 146.914 123.412 1.00 42.12  ?  555 LYS B CD  1 
ATOM   9496  C CE  . LYS B 1 566 ? 156.588 147.286 124.554 1.00 42.12  ?  555 LYS B CE  1 
ATOM   9497  N NZ  . LYS B 1 566 ? 157.893 146.592 124.433 1.00 42.12  1  555 LYS B NZ  1 
ATOM   9498  N N   . LEU B 1 567 ? 153.235 151.068 120.899 1.00 43.14  ?  556 LEU B N   1 
ATOM   9499  C CA  . LEU B 1 567 ? 152.944 151.816 119.683 1.00 43.14  ?  556 LEU B CA  1 
ATOM   9500  C C   . LEU B 1 567 ? 154.048 152.818 119.375 1.00 43.14  ?  556 LEU B C   1 
ATOM   9501  O O   . LEU B 1 567 ? 154.433 152.990 118.213 1.00 43.14  ?  556 LEU B O   1 
ATOM   9502  C CB  . LEU B 1 567 ? 151.595 152.518 119.822 1.00 43.14  ?  556 LEU B CB  1 
ATOM   9503  C CG  . LEU B 1 567 ? 151.014 153.302 118.648 1.00 43.14  ?  556 LEU B CG  1 
ATOM   9504  C CD1 . LEU B 1 567 ? 151.315 152.627 117.335 1.00 43.14  ?  556 LEU B CD1 1 
ATOM   9505  C CD2 . LEU B 1 567 ? 149.525 153.454 118.832 1.00 43.14  ?  556 LEU B CD2 1 
ATOM   9506  N N   . ILE B 1 568 ? 154.580 153.476 120.405 1.00 46.12  ?  557 ILE B N   1 
ATOM   9507  C CA  . ILE B 1 568 ? 155.653 154.441 120.195 1.00 46.12  ?  557 ILE B CA  1 
ATOM   9508  C C   . ILE B 1 568 ? 156.937 153.733 119.779 1.00 46.12  ?  557 ILE B C   1 
ATOM   9509  O O   . ILE B 1 568 ? 157.664 154.208 118.902 1.00 46.12  ?  557 ILE B O   1 
ATOM   9510  C CB  . ILE B 1 568 ? 155.840 155.291 121.463 1.00 46.12  ?  557 ILE B CB  1 
ATOM   9511  C CG1 . ILE B 1 568 ? 154.674 156.267 121.609 1.00 46.12  ?  557 ILE B CG1 1 
ATOM   9512  C CG2 . ILE B 1 568 ? 157.156 156.034 121.431 1.00 46.12  ?  557 ILE B CG2 1 
ATOM   9513  C CD1 . ILE B 1 568 ? 154.732 157.096 122.860 1.00 46.12  ?  557 ILE B CD1 1 
ATOM   9514  N N   . ASP B 1 569 ? 157.231 152.582 120.388 1.00 48.33  ?  558 ASP B N   1 
ATOM   9515  C CA  . ASP B 1 569 ? 158.391 151.804 119.965 1.00 48.33  ?  558 ASP B CA  1 
ATOM   9516  C C   . ASP B 1 569 ? 158.238 151.305 118.533 1.00 48.33  ?  558 ASP B C   1 
ATOM   9517  O O   . ASP B 1 569 ? 159.229 151.159 117.809 1.00 48.33  ?  558 ASP B O   1 
ATOM   9518  C CB  . ASP B 1 569 ? 158.615 150.628 120.912 1.00 48.33  ?  558 ASP B CB  1 
ATOM   9519  C CG  . ASP B 1 569 ? 159.343 151.031 122.176 1.00 48.33  ?  558 ASP B CG  1 
ATOM   9520  O OD1 . ASP B 1 569 ? 158.677 151.419 123.156 1.00 48.33  ?  558 ASP B OD1 1 
ATOM   9521  O OD2 . ASP B 1 569 ? 160.589 150.963 122.188 1.00 48.33  -1 558 ASP B OD2 1 
ATOM   9522  N N   . ALA B 1 570 ? 157.004 151.031 118.108 1.00 46.38  ?  559 ALA B N   1 
ATOM   9523  C CA  . ALA B 1 570 ? 156.778 150.490 116.773 1.00 46.38  ?  559 ALA B CA  1 
ATOM   9524  C C   . ALA B 1 570 ? 156.881 151.568 115.703 1.00 46.38  ?  559 ALA B C   1 
ATOM   9525  O O   . ALA B 1 570 ? 157.514 151.356 114.665 1.00 46.38  ?  559 ALA B O   1 
ATOM   9526  C CB  . ALA B 1 570 ? 155.415 149.810 116.710 1.00 46.38  ?  559 ALA B CB  1 
ATOM   9527  N N   . VAL B 1 571 ? 156.256 152.726 115.927 1.00 46.75  ?  560 VAL B N   1 
ATOM   9528  C CA  . VAL B 1 571 ? 156.320 153.783 114.923 1.00 46.75  ?  560 VAL B CA  1 
ATOM   9529  C C   . VAL B 1 571 ? 157.692 154.442 114.871 1.00 46.75  ?  560 VAL B C   1 
ATOM   9530  O O   . VAL B 1 571 ? 158.065 154.990 113.828 1.00 46.75  ?  560 VAL B O   1 
ATOM   9531  C CB  . VAL B 1 571 ? 155.229 154.841 115.152 1.00 46.75  ?  560 VAL B CB  1 
ATOM   9532  C CG1 . VAL B 1 571 ? 153.868 154.190 115.158 1.00 46.75  ?  560 VAL B CG1 1 
ATOM   9533  C CG2 . VAL B 1 571 ? 155.465 155.592 116.440 1.00 46.75  ?  560 VAL B CG2 1 
ATOM   9534  N N   . GLY B 1 572 ? 158.456 154.398 115.960 1.00 48.96  ?  561 GLY B N   1 
ATOM   9535  C CA  . GLY B 1 572 ? 159.818 154.886 115.967 1.00 48.96  ?  561 GLY B CA  1 
ATOM   9536  C C   . GLY B 1 572 ? 160.022 156.245 116.592 1.00 48.96  ?  561 GLY B C   1 
ATOM   9537  O O   . GLY B 1 572 ? 161.149 156.751 116.570 1.00 48.96  ?  561 GLY B O   1 
ATOM   9538  N N   . PHE B 1 573 ? 158.977 156.851 117.146 1.00 51.43  ?  562 PHE B N   1 
ATOM   9539  C CA  . PHE B 1 573 ? 159.067 158.185 117.712 1.00 51.43  ?  562 PHE B CA  1 
ATOM   9540  C C   . PHE B 1 573 ? 157.860 158.413 118.606 1.00 51.43  ?  562 PHE B C   1 
ATOM   9541  O O   . PHE B 1 573 ? 156.908 157.631 118.606 1.00 51.43  ?  562 PHE B O   1 
ATOM   9542  C CB  . PHE B 1 573 ? 159.147 159.259 116.616 1.00 51.43  ?  562 PHE B CB  1 
ATOM   9543  C CG  . PHE B 1 573 ? 158.021 159.195 115.628 1.00 51.43  ?  562 PHE B CG  1 
ATOM   9544  C CD1 . PHE B 1 573 ? 158.192 158.579 114.407 1.00 51.43  ?  562 PHE B CD1 1 
ATOM   9545  C CD2 . PHE B 1 573 ? 156.794 159.754 115.918 1.00 51.43  ?  562 PHE B CD2 1 
ATOM   9546  C CE1 . PHE B 1 573 ? 157.158 158.513 113.504 1.00 51.43  ?  562 PHE B CE1 1 
ATOM   9547  C CE2 . PHE B 1 573 ? 155.762 159.685 115.022 1.00 51.43  ?  562 PHE B CE2 1 
ATOM   9548  C CZ  . PHE B 1 573 ? 155.944 159.071 113.814 1.00 51.43  ?  562 PHE B CZ  1 
ATOM   9549  N N   . SER B 1 574 ? 157.906 159.503 119.368 1.00 54.13  ?  563 SER B N   1 
ATOM   9550  C CA  . SER B 1 574 ? 156.769 159.922 120.169 1.00 54.13  ?  563 SER B CA  1 
ATOM   9551  C C   . SER B 1 574 ? 156.048 161.045 119.451 1.00 54.13  ?  563 SER B C   1 
ATOM   9552  O O   . SER B 1 574 ? 156.658 162.097 119.211 1.00 54.13  ?  563 SER B O   1 
ATOM   9553  C CB  . SER B 1 574 ? 157.220 160.383 121.546 1.00 54.13  ?  563 SER B CB  1 
ATOM   9554  O OG  . SER B 1 574 ? 156.120 160.482 122.429 1.00 54.13  ?  563 SER B OG  1 
ATOM   9555  N N   . PRO B 1 575 ? 154.778 160.877 119.077 1.00 54.56  ?  564 PRO B N   1 
ATOM   9556  C CA  . PRO B 1 575 ? 154.075 161.946 118.350 1.00 54.56  ?  564 PRO B CA  1 
ATOM   9557  C C   . PRO B 1 575 ? 153.965 163.249 119.125 1.00 54.56  ?  564 PRO B C   1 
ATOM   9558  O O   . PRO B 1 575 ? 154.024 164.320 118.507 1.00 54.56  ?  564 PRO B O   1 
ATOM   9559  C CB  . PRO B 1 575 ? 152.695 161.337 118.081 1.00 54.56  ?  564 PRO B CB  1 
ATOM   9560  C CG  . PRO B 1 575 ? 152.571 160.205 119.033 1.00 54.56  ?  564 PRO B CG  1 
ATOM   9561  C CD  . PRO B 1 575 ? 153.945 159.676 119.224 1.00 54.56  ?  564 PRO B CD  1 
ATOM   9562  N N   . LEU B 1 576 ? 153.829 163.197 120.447 1.00 56.17  ?  565 LEU B N   1 
ATOM   9563  C CA  . LEU B 1 576 ? 153.804 164.407 121.260 1.00 56.17  ?  565 LEU B CA  1 
ATOM   9564  C C   . LEU B 1 576 ? 155.141 165.138 121.248 1.00 56.17  ?  565 LEU B C   1 
ATOM   9565  O O   . LEU B 1 576 ? 155.164 166.370 121.222 1.00 56.17  ?  565 LEU B O   1 
ATOM   9566  C CB  . LEU B 1 576 ? 153.412 164.065 122.697 1.00 56.17  ?  565 LEU B CB  1 
ATOM   9567  C CG  . LEU B 1 576 ? 152.977 165.235 123.574 1.00 56.17  ?  565 LEU B CG  1 
ATOM   9568  C CD1 . LEU B 1 576 ? 151.916 166.061 122.881 1.00 56.17  ?  565 LEU B CD1 1 
ATOM   9569  C CD2 . LEU B 1 576 ? 152.467 164.720 124.900 1.00 56.17  ?  565 LEU B CD2 1 
ATOM   9570  N N   . ARG B 1 577 ? 156.254 164.405 121.248 1.00 57.91  ?  566 ARG B N   1 
ATOM   9571  C CA  . ARG B 1 577 ? 157.566 165.041 121.180 1.00 57.91  ?  566 ARG B CA  1 
ATOM   9572  C C   . ARG B 1 577 ? 157.789 165.708 119.828 1.00 57.91  ?  566 ARG B C   1 
ATOM   9573  O O   . ARG B 1 577 ? 158.340 166.814 119.754 1.00 57.91  ?  566 ARG B O   1 
ATOM   9574  C CB  . ARG B 1 577 ? 158.653 164.009 121.453 1.00 57.91  ?  566 ARG B CB  1 
ATOM   9575  C CG  . ARG B 1 577 ? 160.041 164.580 121.625 1.00 57.91  ?  566 ARG B CG  1 
ATOM   9576  C CD  . ARG B 1 577 ? 160.934 163.574 122.315 1.00 57.91  ?  566 ARG B CD  1 
ATOM   9577  N NE  . ARG B 1 577 ? 160.151 162.683 123.162 1.00 57.91  ?  566 ARG B NE  1 
ATOM   9578  C CZ  . ARG B 1 577 ? 160.642 161.627 123.795 1.00 57.91  ?  566 ARG B CZ  1 
ATOM   9579  N NH1 . ARG B 1 577 ? 161.925 161.321 123.679 1.00 57.91  1  566 ARG B NH1 1 
ATOM   9580  N NH2 . ARG B 1 577 ? 159.850 160.875 124.545 1.00 57.91  ?  566 ARG B NH2 1 
ATOM   9581  N N   . ILE B 1 578 ? 157.371 165.049 118.746 1.00 58.91  ?  567 ILE B N   1 
ATOM   9582  C CA  . ILE B 1 578 ? 157.476 165.655 117.422 1.00 58.91  ?  567 ILE B CA  1 
ATOM   9583  C C   . ILE B 1 578 ? 156.615 166.905 117.345 1.00 58.91  ?  567 ILE B C   1 
ATOM   9584  O O   . ILE B 1 578 ? 157.024 167.925 116.784 1.00 58.91  ?  567 ILE B O   1 
ATOM   9585  C CB  . ILE B 1 578 ? 157.091 164.643 116.329 1.00 58.91  ?  567 ILE B CB  1 
ATOM   9586  C CG1 . ILE B 1 578 ? 157.882 163.349 116.494 1.00 58.91  ?  567 ILE B CG1 1 
ATOM   9587  C CG2 . ILE B 1 578 ? 157.335 165.234 114.959 1.00 58.91  ?  567 ILE B CG2 1 
ATOM   9588  C CD1 . ILE B 1 578 ? 159.269 163.409 115.933 1.00 58.91  ?  567 ILE B CD1 1 
ATOM   9589  N N   . LEU B 1 579 ? 155.411 166.850 117.916 1.00 59.52  ?  568 LEU B N   1 
ATOM   9590  C CA  . LEU B 1 579 ? 154.542 168.022 117.910 1.00 59.52  ?  568 LEU B CA  1 
ATOM   9591  C C   . LEU B 1 579 ? 155.141 169.162 118.721 1.00 59.52  ?  568 LEU B C   1 
ATOM   9592  O O   . LEU B 1 579 ? 155.072 170.324 118.308 1.00 59.52  ?  568 LEU B O   1 
ATOM   9593  C CB  . LEU B 1 579 ? 153.164 167.652 118.444 1.00 59.52  ?  568 LEU B CB  1 
ATOM   9594  C CG  . LEU B 1 579 ? 152.205 168.813 118.680 1.00 59.52  ?  568 LEU B CG  1 
ATOM   9595  C CD1 . LEU B 1 579 ? 151.887 169.514 117.379 1.00 59.52  ?  568 LEU B CD1 1 
ATOM   9596  C CD2 . LEU B 1 579 ? 150.951 168.309 119.351 1.00 59.52  ?  568 LEU B CD2 1 
ATOM   9597  N N   . ARG B 1 580 ? 155.742 168.854 119.870 1.00 59.14  ?  569 ARG B N   1 
ATOM   9598  C CA  . ARG B 1 580 ? 156.345 169.894 120.696 1.00 59.14  ?  569 ARG B CA  1 
ATOM   9599  C C   . ARG B 1 580 ? 157.537 170.536 120.003 1.00 59.14  ?  569 ARG B C   1 
ATOM   9600  O O   . ARG B 1 580 ? 157.711 171.757 120.064 1.00 59.14  ?  569 ARG B O   1 
ATOM   9601  C CB  . ARG B 1 580 ? 156.761 169.315 122.042 1.00 59.14  ?  569 ARG B CB  1 
ATOM   9602  C CG  . ARG B 1 580 ? 155.621 169.187 123.015 1.00 59.14  ?  569 ARG B CG  1 
ATOM   9603  C CD  . ARG B 1 580 ? 155.967 168.262 124.152 1.00 59.14  ?  569 ARG B CD  1 
ATOM   9604  N NE  . ARG B 1 580 ? 154.905 168.223 125.146 1.00 59.14  ?  569 ARG B NE  1 
ATOM   9605  C CZ  . ARG B 1 580 ? 154.799 167.290 126.084 1.00 59.14  ?  569 ARG B CZ  1 
ATOM   9606  N NH1 . ARG B 1 580 ? 155.694 166.318 126.155 1.00 59.14  1  569 ARG B NH1 1 
ATOM   9607  N NH2 . ARG B 1 580 ? 153.798 167.328 126.947 1.00 59.14  ?  569 ARG B NH2 1 
ATOM   9608  N N   . LYS B 1 581 ? 158.369 169.738 119.333 1.00 65.91  ?  570 LYS B N   1 
ATOM   9609  C CA  . LYS B 1 581 ? 159.503 170.325 118.627 1.00 65.91  ?  570 LYS B CA  1 
ATOM   9610  C C   . LYS B 1 581 ? 159.058 171.108 117.399 1.00 65.91  ?  570 LYS B C   1 
ATOM   9611  O O   . LYS B 1 581 ? 159.664 172.133 117.066 1.00 65.91  ?  570 LYS B O   1 
ATOM   9612  C CB  . LYS B 1 581 ? 160.507 169.239 118.258 1.00 65.91  ?  570 LYS B CB  1 
ATOM   9613  C CG  . LYS B 1 581 ? 161.086 168.548 119.479 1.00 65.91  ?  570 LYS B CG  1 
ATOM   9614  C CD  . LYS B 1 581 ? 162.345 167.775 119.158 1.00 65.91  ?  570 LYS B CD  1 
ATOM   9615  C CE  . LYS B 1 581 ? 162.755 166.900 120.330 1.00 65.91  ?  570 LYS B CE  1 
ATOM   9616  N NZ  . LYS B 1 581 ? 163.948 166.072 120.016 1.00 65.91  1  570 LYS B NZ  1 
ATOM   9617  N N   . ARG B 1 582 ? 157.984 170.672 116.736 1.00 69.21  ?  571 ARG B N   1 
ATOM   9618  C CA  . ARG B 1 582 ? 157.426 171.462 115.642 1.00 69.21  ?  571 ARG B CA  1 
ATOM   9619  C C   . ARG B 1 582 ? 156.871 172.784 116.148 1.00 69.21  ?  571 ARG B C   1 
ATOM   9620  O O   . ARG B 1 582 ? 157.016 173.817 115.488 1.00 69.21  ?  571 ARG B O   1 
ATOM   9621  C CB  . ARG B 1 582 ? 156.344 170.665 114.919 1.00 69.21  ?  571 ARG B CB  1 
ATOM   9622  C CG  . ARG B 1 582 ? 156.884 169.553 114.053 1.00 69.21  ?  571 ARG B CG  1 
ATOM   9623  C CD  . ARG B 1 582 ? 155.793 168.856 113.273 1.00 69.21  ?  571 ARG B CD  1 
ATOM   9624  N NE  . ARG B 1 582 ? 156.341 167.753 112.493 1.00 69.21  ?  571 ARG B NE  1 
ATOM   9625  C CZ  . ARG B 1 582 ? 155.632 166.992 111.669 1.00 69.21  ?  571 ARG B CZ  1 
ATOM   9626  N NH1 . ARG B 1 582 ? 154.337 167.215 111.510 1.00 69.21  1  571 ARG B NH1 1 
ATOM   9627  N NH2 . ARG B 1 582 ? 156.219 166.014 110.999 1.00 69.21  ?  571 ARG B NH2 1 
ATOM   9628  N N   . ASN B 1 583 ? 156.238 172.774 117.320 1.00 68.82  ?  572 ASN B N   1 
ATOM   9629  C CA  . ASN B 1 583 ? 155.706 174.008 117.891 1.00 68.82  ?  572 ASN B CA  1 
ATOM   9630  C C   . ASN B 1 583 ? 156.827 174.948 118.319 1.00 68.82  ?  572 ASN B C   1 
ATOM   9631  O O   . ASN B 1 583 ? 156.713 176.168 118.164 1.00 68.82  ?  572 ASN B O   1 
ATOM   9632  C CB  . ASN B 1 583 ? 154.789 173.684 119.065 1.00 68.82  ?  572 ASN B CB  1 
ATOM   9633  C CG  . ASN B 1 583 ? 153.332 173.656 118.673 1.00 68.82  ?  572 ASN B CG  1 
ATOM   9634  O OD1 . ASN B 1 583 ? 152.869 174.506 117.921 1.00 68.82  ?  572 ASN B OD1 1 
ATOM   9635  N ND2 . ASN B 1 583 ? 152.601 172.679 119.186 1.00 68.82  ?  572 ASN B ND2 1 
ATOM   9636  N N   . LYS B 1 584 ? 157.920 174.400 118.853 1.00 72.03  ?  573 LYS B N   1 
ATOM   9637  C CA  . LYS B 1 584 ? 159.093 175.219 119.148 1.00 72.03  ?  573 LYS B CA  1 
ATOM   9638  C C   . LYS B 1 584 ? 159.646 175.856 117.881 1.00 72.03  ?  573 LYS B C   1 
ATOM   9639  O O   . LYS B 1 584 ? 159.964 177.051 117.855 1.00 72.03  ?  573 LYS B O   1 
ATOM   9640  C CB  . LYS B 1 584 ? 160.169 174.374 119.823 1.00 72.03  ?  573 LYS B CB  1 
ATOM   9641  C CG  . LYS B 1 584 ? 160.059 174.293 121.322 1.00 72.03  ?  573 LYS B CG  1 
ATOM   9642  C CD  . LYS B 1 584 ? 161.301 173.650 121.915 1.00 72.03  ?  573 LYS B CD  1 
ATOM   9643  C CE  . LYS B 1 584 ? 161.280 172.141 121.743 1.00 72.03  ?  573 LYS B CE  1 
ATOM   9644  N NZ  . LYS B 1 584 ? 160.296 171.483 122.646 1.00 72.03  1  573 LYS B NZ  1 
ATOM   9645  N N   . ALA B 1 585 ? 159.788 175.059 116.817 1.00 80.36  ?  574 ALA B N   1 
ATOM   9646  C CA  . ALA B 1 585 ? 160.293 175.588 115.557 1.00 80.36  ?  574 ALA B CA  1 
ATOM   9647  C C   . ALA B 1 585 ? 159.375 176.668 115.002 1.00 80.36  ?  574 ALA B C   1 
ATOM   9648  O O   . ALA B 1 585 ? 159.845 177.670 114.458 1.00 80.36  ?  574 ALA B O   1 
ATOM   9649  C CB  . ALA B 1 585 ? 160.462 174.458 114.545 1.00 80.36  ?  574 ALA B CB  1 
ATOM   9650  N N   . LEU B 1 586 ? 158.062 176.487 115.138 1.00 85.14  ?  575 LEU B N   1 
ATOM   9651  C CA  . LEU B 1 586 ? 157.128 177.485 114.630 1.00 85.14  ?  575 LEU B CA  1 
ATOM   9652  C C   . LEU B 1 586 ? 157.186 178.763 115.454 1.00 85.14  ?  575 LEU B C   1 
ATOM   9653  O O   . LEU B 1 586 ? 157.086 179.868 114.905 1.00 85.14  ?  575 LEU B O   1 
ATOM   9654  C CB  . LEU B 1 586 ? 155.713 176.912 114.616 1.00 85.14  ?  575 LEU B CB  1 
ATOM   9655  C CG  . LEU B 1 586 ? 154.634 177.731 113.911 1.00 85.14  ?  575 LEU B CG  1 
ATOM   9656  C CD1 . LEU B 1 586 ? 154.909 177.813 112.421 1.00 85.14  ?  575 LEU B CD1 1 
ATOM   9657  C CD2 . LEU B 1 586 ? 153.271 177.125 114.170 1.00 85.14  ?  575 LEU B CD2 1 
ATOM   9658  N N   . ARG B 1 587 ? 157.352 178.636 116.773 1.00 87.27  ?  576 ARG B N   1 
ATOM   9659  C CA  . ARG B 1 587 ? 157.534 179.813 117.615 1.00 87.27  ?  576 ARG B CA  1 
ATOM   9660  C C   . ARG B 1 587 ? 158.787 180.579 117.220 1.00 87.27  ?  576 ARG B C   1 
ATOM   9661  O O   . ARG B 1 587 ? 158.771 181.811 117.131 1.00 87.27  ?  576 ARG B O   1 
ATOM   9662  C CB  . ARG B 1 587 ? 157.605 179.401 119.083 1.00 87.27  ?  576 ARG B CB  1 
ATOM   9663  C CG  . ARG B 1 587 ? 156.257 179.221 119.743 1.00 87.27  ?  576 ARG B CG  1 
ATOM   9664  C CD  . ARG B 1 587 ? 156.399 179.047 121.241 1.00 87.27  ?  576 ARG B CD  1 
ATOM   9665  N NE  . ARG B 1 587 ? 155.236 179.568 121.949 1.00 87.27  ?  576 ARG B NE  1 
ATOM   9666  C CZ  . ARG B 1 587 ? 155.227 180.705 122.633 1.00 87.27  ?  576 ARG B CZ  1 
ATOM   9667  N NH1 . ARG B 1 587 ? 156.321 181.446 122.707 1.00 87.27  1  576 ARG B NH1 1 
ATOM   9668  N NH2 . ARG B 1 587 ? 154.122 181.105 123.242 1.00 87.27  ?  576 ARG B NH2 1 
ATOM   9669  N N   . LYS B 1 588 ? 159.885 179.863 116.973 1.00 92.84  ?  577 LYS B N   1 
ATOM   9670  C CA  . LYS B 1 588 ? 161.110 180.532 116.546 1.00 92.84  ?  577 LYS B CA  1 
ATOM   9671  C C   . LYS B 1 588 ? 160.949 181.176 115.176 1.00 92.84  ?  577 LYS B C   1 
ATOM   9672  O O   . LYS B 1 588 ? 161.475 182.269 114.943 1.00 92.84  ?  577 LYS B O   1 
ATOM   9673  C CB  . LYS B 1 588 ? 162.278 179.549 116.534 1.00 92.84  ?  577 LYS B CB  1 
ATOM   9674  C CG  . LYS B 1 588 ? 163.604 180.191 116.181 1.00 92.84  ?  577 LYS B CG  1 
ATOM   9675  C CD  . LYS B 1 588 ? 164.728 179.178 116.151 1.00 92.84  ?  577 LYS B CD  1 
ATOM   9676  C CE  . LYS B 1 588 ? 164.952 178.561 117.515 1.00 92.84  ?  577 LYS B CE  1 
ATOM   9677  N NZ  . LYS B 1 588 ? 166.260 177.857 117.583 1.00 92.84  1  577 LYS B NZ  1 
ATOM   9678  N N   . ILE B 1 589 ? 160.223 180.525 114.267 1.00 96.13  ?  578 ILE B N   1 
ATOM   9679  C CA  . ILE B 1 589 ? 160.001 181.095 112.940 1.00 96.13  ?  578 ILE B CA  1 
ATOM   9680  C C   . ILE B 1 589 ? 159.197 182.384 113.044 1.00 96.13  ?  578 ILE B C   1 
ATOM   9681  O O   . ILE B 1 589 ? 159.512 183.384 112.395 1.00 96.13  ?  578 ILE B O   1 
ATOM   9682  C CB  . ILE B 1 589 ? 159.307 180.071 112.025 1.00 96.13  ?  578 ILE B CB  1 
ATOM   9683  C CG1 . ILE B 1 589 ? 160.284 178.975 111.609 1.00 96.13  ?  578 ILE B CG1 1 
ATOM   9684  C CG2 . ILE B 1 589 ? 158.735 180.750 110.795 1.00 96.13  ?  578 ILE B CG2 1 
ATOM   9685  C CD1 . ILE B 1 589 ? 159.618 177.822 110.905 1.00 96.13  ?  578 ILE B CD1 1 
ATOM   9686  N N   . ARG B 1 590 ? 158.147 182.378 113.866 1.00 98.34  ?  579 ARG B N   1 
ATOM   9687  C CA  . ARG B 1 590 ? 157.359 183.590 114.052 1.00 98.34  ?  579 ARG B CA  1 
ATOM   9688  C C   . ARG B 1 590 ? 158.175 184.698 114.703 1.00 98.34  ?  579 ARG B C   1 
ATOM   9689  O O   . ARG B 1 590 ? 158.099 185.857 114.274 1.00 98.34  ?  579 ARG B O   1 
ATOM   9690  C CB  . ARG B 1 590 ? 156.114 183.280 114.883 1.00 98.34  ?  579 ARG B CB  1 
ATOM   9691  C CG  . ARG B 1 590 ? 154.946 182.797 114.052 1.00 98.34  ?  579 ARG B CG  1 
ATOM   9692  C CD  . ARG B 1 590 ? 153.980 181.954 114.858 1.00 98.34  ?  579 ARG B CD  1 
ATOM   9693  N NE  . ARG B 1 590 ? 152.817 181.577 114.060 1.00 98.34  ?  579 ARG B NE  1 
ATOM   9694  C CZ  . ARG B 1 590 ? 151.949 180.633 114.401 1.00 98.34  ?  579 ARG B CZ  1 
ATOM   9695  N NH1 . ARG B 1 590 ? 152.105 179.963 115.533 1.00 98.34  1  579 ARG B NH1 1 
ATOM   9696  N NH2 . ARG B 1 590 ? 150.923 180.358 113.609 1.00 98.34  ?  579 ARG B NH2 1 
ATOM   9697  N N   . LYS B 1 591 ? 159.045 184.368 115.653 1.00 102.82 ?  580 LYS B N   1 
ATOM   9698  C CA  . LYS B 1 591 ? 159.901 185.378 116.294 1.00 102.82 ?  580 LYS B CA  1 
ATOM   9699  C C   . LYS B 1 591 ? 160.716 186.138 115.247 1.00 102.82 ?  580 LYS B C   1 
ATOM   9700  O O   . LYS B 1 591 ? 160.781 187.364 115.264 1.00 102.82 ?  580 LYS B O   1 
ATOM   9701  C CB  . LYS B 1 591 ? 160.837 184.736 117.310 1.00 102.82 ?  580 LYS B CB  1 
ATOM   9702  C CG  . LYS B 1 591 ? 161.633 185.732 118.130 1.00 102.82 ?  580 LYS B CG  1 
ATOM   9703  C CD  . LYS B 1 591 ? 162.401 185.031 119.229 1.00 102.82 ?  580 LYS B CD  1 
ATOM   9704  C CE  . LYS B 1 591 ? 163.331 183.988 118.646 1.00 102.82 ?  580 LYS B CE  1 
ATOM   9705  N NZ  . LYS B 1 591 ? 163.420 182.779 119.510 1.00 102.82 1  580 LYS B NZ  1 
ATOM   9706  N N   . LEU B 1 592 ? 161.300 185.396 114.316 1.00 107.95 ?  581 LEU B N   1 
ATOM   9707  C CA  . LEU B 1 592 ? 162.047 185.980 113.212 1.00 107.95 ?  581 LEU B CA  1 
ATOM   9708  C C   . LEU B 1 592 ? 161.151 186.792 112.280 1.00 107.95 ?  581 LEU B C   1 
ATOM   9709  O O   . LEU B 1 592 ? 161.551 187.826 111.776 1.00 107.95 ?  581 LEU B O   1 
ATOM   9710  C CB  . LEU B 1 592 ? 162.805 184.904 112.445 1.00 107.95 ?  581 LEU B CB  1 
ATOM   9711  C CG  . LEU B 1 592 ? 163.877 184.263 113.312 1.00 107.95 ?  581 LEU B CG  1 
ATOM   9712  C CD1 . LEU B 1 592 ? 164.509 183.102 112.570 1.00 107.95 ?  581 LEU B CD1 1 
ATOM   9713  C CD2 . LEU B 1 592 ? 164.913 185.273 113.760 1.00 107.95 ?  581 LEU B CD2 1 
ATOM   9714  N N   . GLN B 1 593 ? 159.948 186.307 112.023 1.00 109.27 ?  582 GLN B N   1 
ATOM   9715  C CA  . GLN B 1 593 ? 159.024 187.019 111.147 1.00 109.27 ?  582 GLN B CA  1 
ATOM   9716  C C   . GLN B 1 593 ? 158.618 188.376 111.711 1.00 109.27 ?  582 GLN B C   1 
ATOM   9717  O O   . GLN B 1 593 ? 158.511 189.350 110.974 1.00 109.27 ?  582 GLN B O   1 
ATOM   9718  C CB  . GLN B 1 593 ? 157.786 186.174 110.866 1.00 109.27 ?  582 GLN B CB  1 
ATOM   9719  C CG  . GLN B 1 593 ? 156.819 186.805 109.887 1.00 109.27 ?  582 GLN B CG  1 
ATOM   9720  C CD  . GLN B 1 593 ? 155.653 185.898 109.572 1.00 109.27 ?  582 GLN B CD  1 
ATOM   9721  O OE1 . GLN B 1 593 ? 154.646 186.332 109.016 1.00 109.27 ?  582 GLN B OE1 1 
ATOM   9722  N NE2 . GLN B 1 593 ? 155.782 184.628 109.930 1.00 109.27 ?  582 GLN B NE2 1 
ATOM   9723  N N   . LYS B 1 594 ? 158.370 188.433 113.017 1.00 111.82 ?  583 LYS B N   1 
ATOM   9724  C CA  . LYS B 1 594 ? 158.000 189.682 113.686 1.00 111.82 ?  583 LYS B CA  1 
ATOM   9725  C C   . LYS B 1 594 ? 159.149 190.677 113.610 1.00 111.82 ?  583 LYS B C   1 
ATOM   9726  O O   . LYS B 1 594 ? 158.936 191.870 113.435 1.00 111.82 ?  583 LYS B O   1 
ATOM   9727  C CB  . LYS B 1 594 ? 157.595 189.435 115.135 1.00 111.82 ?  583 LYS B CB  1 
ATOM   9728  N N   . GLN B 1 595 ? 160.369 190.169 113.770 1.00 113.64 ?  584 GLN B N   1 
ATOM   9729  C CA  . GLN B 1 595 ? 161.592 190.961 113.678 1.00 113.64 ?  584 GLN B CA  1 
ATOM   9730  C C   . GLN B 1 595 ? 161.772 191.531 112.274 1.00 113.64 ?  584 GLN B C   1 
ATOM   9731  O O   . GLN B 1 595 ? 162.244 192.649 112.108 1.00 113.64 ?  584 GLN B O   1 
ATOM   9732  C CB  . GLN B 1 595 ? 162.821 190.129 114.052 1.00 113.64 ?  584 GLN B CB  1 
ATOM   9733  C CG  . GLN B 1 595 ? 163.021 189.925 115.542 1.00 113.64 ?  584 GLN B CG  1 
ATOM   9734  C CD  . GLN B 1 595 ? 164.395 189.376 115.873 1.00 113.64 ?  584 GLN B CD  1 
ATOM   9735  O OE1 . GLN B 1 595 ? 164.582 188.697 116.882 1.00 113.64 ?  584 GLN B OE1 1 
ATOM   9736  N NE2 . GLN B 1 595 ? 165.367 189.669 115.023 1.00 113.64 ?  584 GLN B NE2 1 
ATOM   9737  N N   . GLY B 1 596 ? 161.389 190.752 111.268 1.00 117.15 ?  585 GLY B N   1 
ATOM   9738  C CA  . GLY B 1 596 ? 161.524 191.136 109.879 1.00 117.15 ?  585 GLY B CA  1 
ATOM   9739  C C   . GLY B 1 596 ? 162.736 190.506 109.227 1.00 117.15 ?  585 GLY B C   1 
ATOM   9740  O O   . GLY B 1 596 ? 162.961 190.675 108.031 1.00 117.15 ?  585 GLY B O   1 
ATOM   9741  N N   . LEU B 1 597 ? 163.517 189.767 110.011 1.00 119.38 ?  586 LEU B N   1 
ATOM   9742  C CA  . LEU B 1 597 ? 164.689 189.060 109.499 1.00 119.38 ?  586 LEU B CA  1 
ATOM   9743  C C   . LEU B 1 597 ? 164.289 187.991 108.492 1.00 119.38 ?  586 LEU B C   1 
ATOM   9744  O O   . LEU B 1 597 ? 165.004 187.726 107.535 1.00 119.38 ?  586 LEU B O   1 
ATOM   9745  C CB  . LEU B 1 597 ? 165.498 188.432 110.625 1.00 119.38 ?  586 LEU B CB  1 
ATOM   9746  C CG  . LEU B 1 597 ? 166.395 189.408 111.368 1.00 119.38 ?  586 LEU B CG  1 
ATOM   9747  C CD1 . LEU B 1 597 ? 165.544 190.548 111.902 1.00 119.38 ?  586 LEU B CD1 1 
ATOM   9748  C CD2 . LEU B 1 597 ? 167.143 188.695 112.482 1.00 119.38 ?  586 LEU B CD2 1 
ATOM   9749  N N   . LEU B 1 598 ? 163.176 187.327 108.761 1.00 117.97 ?  587 LEU B N   1 
ATOM   9750  C CA  . LEU B 1 598 ? 162.653 186.302 107.882 1.00 117.97 ?  587 LEU B CA  1 
ATOM   9751  C C   . LEU B 1 598 ? 161.458 186.910 107.163 1.00 117.97 ?  587 LEU B C   1 
ATOM   9752  O O   . LEU B 1 598 ? 160.468 187.276 107.792 1.00 117.97 ?  587 LEU B O   1 
ATOM   9753  C CB  . LEU B 1 598 ? 162.240 185.080 108.707 1.00 117.97 ?  587 LEU B CB  1 
ATOM   9754  C CG  . LEU B 1 598 ? 161.943 183.751 108.023 1.00 117.97 ?  587 LEU B CG  1 
ATOM   9755  C CD1 . LEU B 1 598 ? 162.079 182.625 109.034 1.00 117.97 ?  587 LEU B CD1 1 
ATOM   9756  C CD2 . LEU B 1 598 ? 160.549 183.765 107.416 1.00 117.97 ?  587 LEU B CD2 1 
ATOM   9757  N N   . GLN B 1 599 ? 161.564 187.063 105.849 1.00 124.15 ?  588 GLN B N   1 
ATOM   9758  C CA  . GLN B 1 599 ? 160.469 187.631 105.079 1.00 124.15 ?  588 GLN B CA  1 
ATOM   9759  C C   . GLN B 1 599 ? 159.628 186.520 104.464 1.00 124.15 ?  588 GLN B C   1 
ATOM   9760  O O   . GLN B 1 599 ? 160.150 185.554 103.901 1.00 124.15 ?  588 GLN B O   1 
ATOM   9761  C CB  . GLN B 1 599 ? 160.993 188.567 103.980 1.00 124.15 ?  588 GLN B CB  1 
ATOM   9762  N N   . VAL B 1 600 ? 158.307 186.674 104.574 1.00 125.07 ?  589 VAL B N   1 
ATOM   9763  C CA  . VAL B 1 600 ? 157.390 185.664 104.060 1.00 125.07 ?  589 VAL B CA  1 
ATOM   9764  C C   . VAL B 1 600 ? 157.222 185.831 102.555 1.00 125.07 ?  589 VAL B C   1 
ATOM   9765  O O   . VAL B 1 600 ? 157.064 186.949 102.042 1.00 125.07 ?  589 VAL B O   1 
ATOM   9766  C CB  . VAL B 1 600 ? 156.043 185.730 104.806 1.00 125.07 ?  589 VAL B CB  1 
ATOM   9767  N N   . THR B 1 601 ? 157.309 184.715 101.828 1.00 125.12 ?  590 THR B N   1 
ATOM   9768  C CA  . THR B 1 601 ? 157.140 184.693 100.379 1.00 125.12 ?  590 THR B CA  1 
ATOM   9769  C C   . THR B 1 601 ? 156.339 183.436 100.059 1.00 125.12 ?  590 THR B C   1 
ATOM   9770  O O   . THR B 1 601 ? 156.588 182.376 100.663 1.00 125.12 ?  590 THR B O   1 
ATOM   9771  C CB  . THR B 1 601 ? 158.463 184.681 99.601  1.00 125.12 ?  590 THR B CB  1 
ATOM   9772  O OG1 . THR B 1 601 ? 158.893 183.327 99.414  1.00 125.12 ?  590 THR B OG1 1 
ATOM   9773  C CG2 . THR B 1 601 ? 159.554 185.462 100.330 1.00 125.12 ?  590 THR B CG2 1 
ATOM   9774  N N   . PRO B 1 602 ? 155.390 183.505 99.122  1.00 125.34 ?  591 PRO B N   1 
ATOM   9775  C CA  . PRO B 1 602 ? 154.604 182.307 98.779  1.00 125.34 ?  591 PRO B CA  1 
ATOM   9776  C C   . PRO B 1 602 ? 155.422 181.192 98.141  1.00 125.34 ?  591 PRO B C   1 
ATOM   9777  O O   . PRO B 1 602 ? 154.854 180.134 97.838  1.00 125.34 ?  591 PRO B O   1 
ATOM   9778  C CB  . PRO B 1 602 ? 153.547 182.846 97.804  1.00 125.34 ?  591 PRO B CB  1 
ATOM   9779  C CG  . PRO B 1 602 ? 153.497 184.322 98.066  1.00 125.34 ?  591 PRO B CG  1 
ATOM   9780  C CD  . PRO B 1 602 ? 154.897 184.705 98.428  1.00 125.34 ?  591 PRO B CD  1 
ATOM   9781  N N   . LYS B 1 603 ? 156.724 181.387 97.930  1.00 123.84 ?  592 LYS B N   1 
ATOM   9782  C CA  . LYS B 1 603 ? 157.579 180.370 97.340  1.00 123.84 ?  592 LYS B CA  1 
ATOM   9783  C C   . LYS B 1 603 ? 158.439 179.640 98.362  1.00 123.84 ?  592 LYS B C   1 
ATOM   9784  O O   . LYS B 1 603 ? 158.741 178.459 98.161  1.00 123.84 ?  592 LYS B O   1 
ATOM   9785  C CB  . LYS B 1 603 ? 158.485 180.991 96.266  1.00 123.84 ?  592 LYS B CB  1 
ATOM   9786  N N   . GLY B 1 604 ? 158.838 180.296 99.447  1.00 123.35 ?  593 GLY B N   1 
ATOM   9787  C CA  . GLY B 1 604 ? 159.686 179.649 100.432 1.00 123.35 ?  593 GLY B CA  1 
ATOM   9788  C C   . GLY B 1 604 ? 159.992 180.577 101.585 1.00 123.35 ?  593 GLY B C   1 
ATOM   9789  O O   . GLY B 1 604 ? 159.423 181.664 101.710 1.00 123.35 ?  593 GLY B O   1 
ATOM   9790  N N   . PHE B 1 605 ? 160.902 180.117 102.434 1.00 119.61 ?  594 PHE B N   1 
ATOM   9791  C CA  . PHE B 1 605 ? 161.334 180.855 103.623 1.00 119.61 ?  594 PHE B CA  1 
ATOM   9792  C C   . PHE B 1 605 ? 162.632 181.614 103.371 1.00 119.61 ?  594 PHE B C   1 
ATOM   9793  O O   . PHE B 1 605 ? 163.669 181.297 103.951 1.00 119.61 ?  594 PHE B O   1 
ATOM   9794  C CB  . PHE B 1 605 ? 161.488 179.899 104.799 1.00 119.61 ?  594 PHE B CB  1 
ATOM   9795  C CG  . PHE B 1 605 ? 160.245 179.741 105.622 1.00 119.61 ?  594 PHE B CG  1 
ATOM   9796  C CD1 . PHE B 1 605 ? 159.552 180.848 106.074 1.00 119.61 ?  594 PHE B CD1 1 
ATOM   9797  C CD2 . PHE B 1 605 ? 159.775 178.484 105.952 1.00 119.61 ?  594 PHE B CD2 1 
ATOM   9798  C CE1 . PHE B 1 605 ? 158.414 180.707 106.838 1.00 119.61 ?  594 PHE B CE1 1 
ATOM   9799  C CE2 . PHE B 1 605 ? 158.635 178.334 106.713 1.00 119.61 ?  594 PHE B CE2 1 
ATOM   9800  C CZ  . PHE B 1 605 ? 157.954 179.447 107.157 1.00 119.61 ?  594 PHE B CZ  1 
ATOM   9801  N N   . ILE B 1 606 ? 162.592 182.626 102.506 1.00 124.80 ?  595 ILE B N   1 
ATOM   9802  C CA  . ILE B 1 606 ? 163.773 183.434 102.211 1.00 124.80 ?  595 ILE B CA  1 
ATOM   9803  C C   . ILE B 1 606 ? 164.115 184.270 103.438 1.00 124.80 ?  595 ILE B C   1 
ATOM   9804  O O   . ILE B 1 606 ? 163.226 184.844 104.078 1.00 124.80 ?  595 ILE B O   1 
ATOM   9805  C CB  . ILE B 1 606 ? 163.563 184.331 100.973 1.00 124.80 ?  595 ILE B CB  1 
ATOM   9806  C CG1 . ILE B 1 606 ? 163.436 183.502 99.690  1.00 124.80 ?  595 ILE B CG1 1 
ATOM   9807  C CG2 . ILE B 1 606 ? 164.693 185.339 100.834 1.00 124.80 ?  595 ILE B CG2 1 
ATOM   9808  C CD1 . ILE B 1 606 ? 162.073 182.886 99.454  1.00 124.80 ?  595 ILE B CD1 1 
ATOM   9809  N N   . CYS B 1 607 ? 165.402 184.350 103.765 1.00 128.14 ?  596 CYS B N   1 
ATOM   9810  C CA  . CYS B 1 607 ? 165.884 185.104 104.914 1.00 128.14 ?  596 CYS B CA  1 
ATOM   9811  C C   . CYS B 1 607 ? 166.832 186.193 104.433 1.00 128.14 ?  596 CYS B C   1 
ATOM   9812  O O   . CYS B 1 607 ? 167.791 185.910 103.706 1.00 128.14 ?  596 CYS B O   1 
ATOM   9813  C CB  . CYS B 1 607 ? 166.594 184.190 105.916 1.00 128.14 ?  596 CYS B CB  1 
ATOM   9814  S SG  . CYS B 1 607 ? 167.943 183.216 105.215 1.00 128.14 ?  596 CYS B SG  1 
ATOM   9815  N N   . THR B 1 608 ? 166.559 187.435 104.838 1.00 128.97 ?  597 THR B N   1 
ATOM   9816  C CA  . THR B 1 608 ? 167.393 188.551 104.404 1.00 128.97 ?  597 THR B CA  1 
ATOM   9817  C C   . THR B 1 608 ? 168.738 188.543 105.121 1.00 128.97 ?  597 THR B C   1 
ATOM   9818  O O   . THR B 1 608 ? 169.751 188.983 104.565 1.00 128.97 ?  597 THR B O   1 
ATOM   9819  C CB  . THR B 1 608 ? 166.664 189.875 104.636 1.00 128.97 ?  597 THR B CB  1 
ATOM   9820  O OG1 . THR B 1 608 ? 165.254 189.687 104.451 1.00 128.97 ?  597 THR B OG1 1 
ATOM   9821  C CG2 . THR B 1 608 ? 167.158 190.928 103.654 1.00 128.97 ?  597 THR B CG2 1 
ATOM   9822  N N   . VAL B 1 609 ? 168.770 188.044 106.352 1.00 128.94 ?  598 VAL B N   1 
ATOM   9823  C CA  . VAL B 1 609 ? 169.992 187.968 107.140 1.00 128.94 ?  598 VAL B CA  1 
ATOM   9824  C C   . VAL B 1 609 ? 170.149 186.548 107.662 1.00 128.94 ?  598 VAL B C   1 
ATOM   9825  O O   . VAL B 1 609 ? 169.198 185.956 108.184 1.00 128.94 ?  598 VAL B O   1 
ATOM   9826  C CB  . VAL B 1 609 ? 169.987 188.991 108.297 1.00 128.94 ?  598 VAL B CB  1 
ATOM   9827  C CG1 . VAL B 1 609 ? 168.657 188.969 109.021 1.00 128.94 ?  598 VAL B CG1 1 
ATOM   9828  C CG2 . VAL B 1 609 ? 171.129 188.718 109.265 1.00 128.94 ?  598 VAL B CG2 1 
ATOM   9829  N N   . ASP B 1 610 ? 171.353 185.998 107.504 1.00 130.51 ?  599 ASP B N   1 
ATOM   9830  C CA  . ASP B 1 610 ? 171.671 184.648 107.943 1.00 130.51 ?  599 ASP B CA  1 
ATOM   9831  C C   . ASP B 1 610 ? 172.551 184.632 109.187 1.00 130.51 ?  599 ASP B C   1 
ATOM   9832  O O   . ASP B 1 610 ? 173.431 183.772 109.307 1.00 130.51 ?  599 ASP B O   1 
ATOM   9833  C CB  . ASP B 1 610 ? 172.343 183.875 106.806 1.00 130.51 ?  599 ASP B CB  1 
ATOM   9834  N N   . THR B 1 611 ? 172.324 185.552 110.120 1.00 130.43 ?  600 THR B N   1 
ATOM   9835  C CA  . THR B 1 611 ? 173.148 185.697 111.313 1.00 130.43 ?  600 THR B CA  1 
ATOM   9836  C C   . THR B 1 611 ? 172.345 185.368 112.569 1.00 130.43 ?  600 THR B C   1 
ATOM   9837  O O   . THR B 1 611 ? 172.388 186.090 113.568 1.00 130.43 ?  600 THR B O   1 
ATOM   9838  C CB  . THR B 1 611 ? 173.741 187.101 111.399 1.00 130.43 ?  600 THR B CB  1 
ATOM   9839  N N   . ILE B 1 612 ? 171.587 184.272 112.523 1.00 125.45 ?  601 ILE B N   1 
ATOM   9840  C CA  . ILE B 1 612 ? 170.818 183.854 113.688 1.00 125.45 ?  601 ILE B CA  1 
ATOM   9841  C C   . ILE B 1 612 ? 171.763 183.387 114.789 1.00 125.45 ?  601 ILE B C   1 
ATOM   9842  O O   . ILE B 1 612 ? 172.688 182.595 114.561 1.00 125.45 ?  601 ILE B O   1 
ATOM   9843  C CB  . ILE B 1 612 ? 169.811 182.750 113.309 1.00 125.45 ?  601 ILE B CB  1 
ATOM   9844  C CG1 . ILE B 1 612 ? 169.113 182.207 114.560 1.00 125.45 ?  601 ILE B CG1 1 
ATOM   9845  C CG2 . ILE B 1 612 ? 170.501 181.629 112.548 1.00 125.45 ?  601 ILE B CG2 1 
ATOM   9846  C CD1 . ILE B 1 612 ? 168.185 181.038 114.289 1.00 125.45 ?  601 ILE B CD1 1 
ATOM   9847  N N   . LYS B 1 613 ? 171.537 183.893 115.996 1.00 124.65 ?  602 LYS B N   1 
ATOM   9848  C CA  . LYS B 1 613 ? 172.335 183.525 117.154 1.00 124.65 ?  602 LYS B CA  1 
ATOM   9849  C C   . LYS B 1 613 ? 171.601 182.473 117.977 1.00 124.65 ?  602 LYS B C   1 
ATOM   9850  O O   . LYS B 1 613 ? 170.369 182.463 118.050 1.00 124.65 ?  602 LYS B O   1 
ATOM   9851  C CB  . LYS B 1 613 ? 172.645 184.748 118.021 1.00 124.65 ?  602 LYS B CB  1 
ATOM   9852  N N   . ASP B 1 614 ? 172.374 181.580 118.588 1.00 121.67 ?  603 ASP B N   1 
ATOM   9853  C CA  . ASP B 1 614 ? 171.800 180.503 119.384 1.00 121.67 ?  603 ASP B CA  1 
ATOM   9854  C C   . ASP B 1 614 ? 171.022 181.066 120.566 1.00 121.67 ?  603 ASP B C   1 
ATOM   9855  O O   . ASP B 1 614 ? 171.577 181.767 121.418 1.00 121.67 ?  603 ASP B O   1 
ATOM   9856  C CB  . ASP B 1 614 ? 172.905 179.567 119.876 1.00 121.67 ?  603 ASP B CB  1 
ATOM   9857  N N   . SER B 1 615 ? 169.730 180.752 120.617 1.00 113.81 ?  604 SER B N   1 
ATOM   9858  C CA  . SER B 1 615 ? 168.870 181.242 121.685 1.00 113.81 ?  604 SER B CA  1 
ATOM   9859  C C   . SER B 1 615 ? 167.580 180.436 121.697 1.00 113.81 ?  604 SER B C   1 
ATOM   9860  O O   . SER B 1 615 ? 166.929 180.265 120.664 1.00 113.81 ?  604 SER B O   1 
ATOM   9861  C CB  . SER B 1 615 ? 168.561 182.735 121.515 1.00 113.81 ?  604 SER B CB  1 
ATOM   9862  O OG  . SER B 1 615 ? 167.729 183.207 122.558 1.00 113.81 ?  604 SER B OG  1 
ATOM   9863  N N   . ASP B 1 616 ? 167.192 179.958 122.876 1.00 105.99 ?  605 ASP B N   1 
ATOM   9864  C CA  . ASP B 1 616 ? 165.933 179.230 123.007 1.00 105.99 ?  605 ASP B CA  1 
ATOM   9865  C C   . ASP B 1 616 ? 164.988 180.028 123.894 1.00 105.99 ?  605 ASP B C   1 
ATOM   9866  O O   . ASP B 1 616 ? 165.436 180.746 124.783 1.00 105.99 ?  605 ASP B O   1 
ATOM   9867  C CB  . ASP B 1 616 ? 166.165 177.838 123.583 1.00 105.99 ?  605 ASP B CB  1 
ATOM   9868  C CG  . ASP B 1 616 ? 167.048 176.981 122.700 1.00 105.99 ?  605 ASP B CG  1 
ATOM   9869  O OD1 . ASP B 1 616 ? 167.385 175.852 123.114 1.00 105.99 ?  605 ASP B OD1 1 
ATOM   9870  O OD2 . ASP B 1 616 ? 167.406 177.433 121.594 1.00 105.99 -1 605 ASP B OD2 1 
ATOM   9871  N N   . GLU B 1 617 ? 163.685 179.908 123.662 1.00 96.18  ?  606 GLU B N   1 
ATOM   9872  C CA  . GLU B 1 617 ? 162.716 180.701 124.423 1.00 96.18  ?  606 GLU B CA  1 
ATOM   9873  C C   . GLU B 1 617 ? 162.716 180.395 125.914 1.00 96.18  ?  606 GLU B C   1 
ATOM   9874  O O   . GLU B 1 617 ? 162.526 181.296 126.726 1.00 96.18  ?  606 GLU B O   1 
ATOM   9875  C CB  . GLU B 1 617 ? 161.302 180.514 123.866 1.00 96.18  ?  606 GLU B CB  1 
ATOM   9876  C CG  . GLU B 1 617 ? 161.065 181.180 122.523 1.00 96.18  ?  606 GLU B CG  1 
ATOM   9877  C CD  . GLU B 1 617 ? 159.602 181.184 122.129 1.00 96.18  ?  606 GLU B CD  1 
ATOM   9878  O OE1 . GLU B 1 617 ? 158.785 180.586 122.862 1.00 96.18  ?  606 GLU B OE1 1 
ATOM   9879  O OE2 . GLU B 1 617 ? 159.269 181.785 121.085 1.00 96.18  -1 606 GLU B OE2 1 
ATOM   9880  N N   . GLU B 1 618 ? 162.902 179.119 126.264 1.00 92.89  ?  607 GLU B N   1 
ATOM   9881  C CA  . GLU B 1 618 ? 162.865 178.642 127.659 1.00 92.89  ?  607 GLU B CA  1 
ATOM   9882  C C   . GLU B 1 618 ? 161.557 179.063 128.343 1.00 92.89  ?  607 GLU B C   1 
ATOM   9883  O O   . GLU B 1 618 ? 161.555 179.904 129.230 1.00 92.89  ?  607 GLU B O   1 
ATOM   9884  C CB  . GLU B 1 618 ? 164.096 179.094 128.455 1.00 92.89  ?  607 GLU B CB  1 
ATOM   9885  C CG  . GLU B 1 618 ? 164.020 178.820 129.950 1.00 92.89  ?  607 GLU B CG  1 
ATOM   9886  C CD  . GLU B 1 618 ? 164.627 177.488 130.344 1.00 92.89  ?  607 GLU B CD  1 
ATOM   9887  O OE1 . GLU B 1 618 ? 164.103 176.837 131.274 1.00 92.89  ?  607 GLU B OE1 1 
ATOM   9888  O OE2 . GLU B 1 618 ? 165.631 177.094 129.721 1.00 92.89  -1 607 GLU B OE2 1 
ATOM   9889  N N   . LEU B 1 619 ? 160.455 178.436 127.936 1.00 81.82  ?  608 LEU B N   1 
ATOM   9890  C CA  . LEU B 1 619 ? 159.120 178.750 128.427 1.00 81.82  ?  608 LEU B CA  1 
ATOM   9891  C C   . LEU B 1 619 ? 158.957 178.381 129.889 1.00 81.82  ?  608 LEU B C   1 
ATOM   9892  O O   . LEU B 1 619 ? 159.538 177.407 130.354 1.00 81.82  ?  608 LEU B O   1 
ATOM   9893  C CB  . LEU B 1 619 ? 158.066 178.020 127.596 1.00 81.82  ?  608 LEU B CB  1 
ATOM   9894  C CG  . LEU B 1 619 ? 157.840 178.470 126.150 1.00 81.82  ?  608 LEU B CG  1 
ATOM   9895  C CD1 . LEU B 1 619 ? 159.015 178.081 125.268 1.00 81.82  ?  608 LEU B CD1 1 
ATOM   9896  C CD2 . LEU B 1 619 ? 156.558 177.857 125.614 1.00 81.82  ?  608 LEU B CD2 1 
ATOM   9897  N N   . ASP B 1 620 ? 158.161 179.155 130.614 1.00 74.58  ?  609 ASP B N   1 
ATOM   9898  C CA  . ASP B 1 620 ? 157.972 178.889 132.034 1.00 74.58  ?  609 ASP B CA  1 
ATOM   9899  C C   . ASP B 1 620 ? 157.024 177.722 132.255 1.00 74.58  ?  609 ASP B C   1 
ATOM   9900  O O   . ASP B 1 620 ? 156.377 177.260 131.322 1.00 74.58  ?  609 ASP B O   1 
ATOM   9901  C CB  . ASP B 1 620 ? 157.500 180.149 132.777 1.00 74.58  ?  609 ASP B CB  1 
ATOM   9902  C CG  . ASP B 1 620 ? 156.119 180.607 132.361 1.00 74.58  ?  609 ASP B CG  1 
ATOM   9903  O OD1 . ASP B 1 620 ? 155.935 181.828 132.187 1.00 74.58  ?  609 ASP B OD1 1 
ATOM   9904  O OD2 . ASP B 1 620 ? 155.216 179.763 132.219 1.00 74.58  -1 609 ASP B OD2 1 
ATOM   9905  N N   . ASN B 1 621 ? 156.937 177.249 133.486 1.00 66.63  ?  610 ASN B N   1 
ATOM   9906  C CA  . ASN B 1 621 ? 156.090 176.106 133.791 1.00 66.63  ?  610 ASN B CA  1 
ATOM   9907  C C   . ASN B 1 621 ? 154.633 176.355 133.443 1.00 66.63  ?  610 ASN B C   1 
ATOM   9908  O O   . ASN B 1 621 ? 153.903 175.422 133.133 1.00 66.63  ?  610 ASN B O   1 
ATOM   9909  C CB  . ASN B 1 621 ? 156.220 175.743 135.271 1.00 66.63  ?  610 ASN B CB  1 
ATOM   9910  C CG  . ASN B 1 621 ? 157.625 175.316 135.649 1.00 66.63  ?  610 ASN B CG  1 
ATOM   9911  O OD1 . ASN B 1 621 ? 158.564 175.469 134.870 1.00 66.63  ?  610 ASN B OD1 1 
ATOM   9912  N ND2 . ASN B 1 621 ? 157.776 174.775 136.850 1.00 66.63  ?  610 ASN B ND2 1 
ATOM   9913  N N   . ASN B 1 622 ? 154.205 177.608 133.497 1.00 73.94  ?  611 ASN B N   1 
ATOM   9914  C CA  . ASN B 1 622 ? 152.812 177.940 133.219 1.00 73.94  ?  611 ASN B CA  1 
ATOM   9915  C C   . ASN B 1 622 ? 152.574 178.284 131.757 1.00 73.94  ?  611 ASN B C   1 
ATOM   9916  O O   . ASN B 1 622 ? 151.448 178.571 131.365 1.00 73.94  ?  611 ASN B O   1 
ATOM   9917  C CB  . ASN B 1 622 ? 152.374 179.100 134.111 1.00 73.94  ?  611 ASN B CB  1 
ATOM   9918  C CG  . ASN B 1 622 ? 152.408 178.749 135.586 1.00 73.94  ?  611 ASN B CG  1 
ATOM   9919  O OD1 . ASN B 1 622 ? 152.398 179.630 136.445 1.00 73.94  ?  611 ASN B OD1 1 
ATOM   9920  N ND2 . ASN B 1 622 ? 152.453 177.457 135.889 1.00 73.94  ?  611 ASN B ND2 1 
ATOM   9921  N N   . GLN B 1 623 ? 153.637 178.276 130.957 1.00 74.41  ?  612 GLN B N   1 
ATOM   9922  C CA  . GLN B 1 623 ? 153.548 178.582 129.542 1.00 74.41  ?  612 GLN B CA  1 
ATOM   9923  C C   . GLN B 1 623 ? 153.969 177.419 128.668 1.00 74.41  ?  612 GLN B C   1 
ATOM   9924  O O   . GLN B 1 623 ? 153.739 177.453 127.482 1.00 74.41  ?  612 GLN B O   1 
ATOM   9925  C CB  . GLN B 1 623 ? 154.506 179.729 129.189 1.00 74.41  ?  612 GLN B CB  1 
ATOM   9926  C CG  . GLN B 1 623 ? 154.177 181.094 129.753 1.00 74.41  ?  612 GLN B CG  1 
ATOM   9927  C CD  . GLN B 1 623 ? 155.358 182.046 129.677 1.00 74.41  ?  612 GLN B CD  1 
ATOM   9928  O OE1 . GLN B 1 623 ? 155.239 183.229 129.996 1.00 74.41  ?  612 GLN B OE1 1 
ATOM   9929  N NE2 . GLN B 1 623 ? 156.509 181.530 129.266 1.00 74.41  ?  612 GLN B NE2 1 
ATOM   9930  N N   . ILE B 1 624 ? 154.584 176.393 129.243 1.00 70.31  ?  613 ILE B N   1 
ATOM   9931  C CA  . ILE B 1 624 ? 155.126 175.296 128.445 1.00 70.31  ?  613 ILE B CA  1 
ATOM   9932  C C   . ILE B 1 624 ? 154.059 174.447 127.755 1.00 70.31  ?  613 ILE B C   1 
ATOM   9933  O O   . ILE B 1 624 ? 154.362 173.714 126.823 1.00 70.31  ?  613 ILE B O   1 
ATOM   9934  C CB  . ILE B 1 624 ? 156.043 174.395 129.307 1.00 70.31  ?  613 ILE B CB  1 
ATOM   9935  C CG1 . ILE B 1 624 ? 156.964 173.561 128.413 1.00 70.31  ?  613 ILE B CG1 1 
ATOM   9936  C CG2 . ILE B 1 624 ? 155.217 173.517 130.235 1.00 70.31  ?  613 ILE B CG2 1 
ATOM   9937  C CD1 . ILE B 1 624 ? 157.908 172.665 129.181 1.00 70.31  ?  613 ILE B CD1 1 
ATOM   9938  N N   . GLU B 1 625 ? 152.811 174.563 128.187 1.00 68.61  ?  614 GLU B N   1 
ATOM   9939  C CA  . GLU B 1 625 ? 151.745 173.737 127.622 1.00 68.61  ?  614 GLU B CA  1 
ATOM   9940  C C   . GLU B 1 625 ? 151.254 174.235 126.268 1.00 68.61  ?  614 GLU B C   1 
ATOM   9941  O O   . GLU B 1 625 ? 150.405 173.603 125.647 1.00 68.61  ?  614 GLU B O   1 
ATOM   9942  C CB  . GLU B 1 625 ? 150.573 173.655 128.598 1.00 30.00  ?  614 GLU B CB  1 
ATOM   9943  C CG  . GLU B 1 625 ? 149.935 174.996 128.917 1.00 30.00  ?  614 GLU B CG  1 
ATOM   9944  C CD  . GLU B 1 625 ? 148.763 174.864 129.870 1.00 30.00  ?  614 GLU B CD  1 
ATOM   9945  O OE1 . GLU B 1 625 ? 148.408 173.721 130.223 1.00 30.00  ?  614 GLU B OE1 1 
ATOM   9946  O OE2 . GLU B 1 625 ? 148.195 175.903 130.267 1.00 30.00  -1 614 GLU B OE2 1 
ATOM   9947  N N   . VAL B 1 626 ? 151.776 175.364 125.813 1.00 68.89  ?  615 VAL B N   1 
ATOM   9948  C CA  . VAL B 1 626 ? 151.391 175.892 124.516 1.00 68.89  ?  615 VAL B CA  1 
ATOM   9949  C C   . VAL B 1 626 ? 152.013 175.048 123.417 1.00 68.89  ?  615 VAL B C   1 
ATOM   9950  O O   . VAL B 1 626 ? 151.640 175.162 122.253 1.00 68.89  ?  615 VAL B O   1 
ATOM   9951  C CB  . VAL B 1 626 ? 151.835 177.354 124.353 1.00 68.89  ?  615 VAL B CB  1 
ATOM   9952  C CG1 . VAL B 1 626 ? 153.342 177.433 124.161 1.00 68.89  ?  615 VAL B CG1 1 
ATOM   9953  C CG2 . VAL B 1 626 ? 151.113 178.007 123.186 1.00 68.89  ?  615 VAL B CG2 1 
ATOM   9954  N N   . LEU B 1 627 ? 152.954 174.189 123.786 1.00 65.40  ?  616 LEU B N   1 
ATOM   9955  C CA  . LEU B 1 627 ? 153.622 173.352 122.797 1.00 65.40  ?  616 LEU B CA  1 
ATOM   9956  C C   . LEU B 1 627 ? 152.842 172.085 122.435 1.00 65.40  ?  616 LEU B C   1 
ATOM   9957  O O   . LEU B 1 627 ? 153.234 171.378 121.516 1.00 65.40  ?  616 LEU B O   1 
ATOM   9958  C CB  . LEU B 1 627 ? 155.037 172.999 123.259 1.00 65.40  ?  616 LEU B CB  1 
ATOM   9959  C CG  . LEU B 1 627 ? 155.982 174.180 123.484 1.00 65.40  ?  616 LEU B CG  1 
ATOM   9960  C CD1 . LEU B 1 627 ? 157.355 173.687 123.912 1.00 65.40  ?  616 LEU B CD1 1 
ATOM   9961  C CD2 . LEU B 1 627 ? 156.087 175.039 122.235 1.00 65.40  ?  616 LEU B CD2 1 
ATOM   9962  N N   . ASP B 1 628 ? 151.750 171.791 123.131 1.00 66.62  ?  617 ASP B N   1 
ATOM   9963  C CA  . ASP B 1 628 ? 150.934 170.651 122.740 1.00 66.62  ?  617 ASP B CA  1 
ATOM   9964  C C   . ASP B 1 628 ? 149.716 171.047 121.919 1.00 66.62  ?  617 ASP B C   1 
ATOM   9965  O O   . ASP B 1 628 ? 148.855 170.199 121.663 1.00 66.62  ?  617 ASP B O   1 
ATOM   9966  C CB  . ASP B 1 628 ? 150.476 169.873 123.973 1.00 66.62  ?  617 ASP B CB  1 
ATOM   9967  C CG  . ASP B 1 628 ? 151.601 169.592 124.929 1.00 66.62  ?  617 ASP B CG  1 
ATOM   9968  O OD1 . ASP B 1 628 ? 151.340 169.513 126.145 1.00 66.62  ?  617 ASP B OD1 1 
ATOM   9969  O OD2 . ASP B 1 628 ? 152.749 169.450 124.468 1.00 66.62  -1 617 ASP B OD2 1 
ATOM   9970  N N   . GLN B 1 629 ? 149.594 172.315 121.577 1.00 71.06  ?  618 GLN B N   1 
ATOM   9971  C CA  . GLN B 1 629 ? 148.444 172.752 120.804 1.00 71.06  ?  618 GLN B CA  1 
ATOM   9972  C C   . GLN B 1 629 ? 148.601 172.407 119.347 1.00 71.06  ?  618 GLN B C   1 
ATOM   9973  O O   . GLN B 1 629 ? 149.714 172.287 118.870 1.00 71.06  ?  618 GLN B O   1 
ATOM   9974  C CB  . GLN B 1 629 ? 148.273 174.266 120.918 1.00 71.06  ?  618 GLN B CB  1 
ATOM   9975  C CG  . GLN B 1 629 ? 148.141 174.767 122.339 1.00 71.06  ?  618 GLN B CG  1 
ATOM   9976  C CD  . GLN B 1 629 ? 147.128 173.975 123.132 1.00 71.06  ?  618 GLN B CD  1 
ATOM   9977  O OE1 . GLN B 1 629 ? 145.949 173.929 122.782 1.00 71.06  ?  618 GLN B OE1 1 
ATOM   9978  N NE2 . GLN B 1 629 ? 147.580 173.351 124.213 1.00 71.06  ?  618 GLN B NE2 1 
ATOM   9979  N N   . PRO B 1 630 ? 147.477 172.286 118.606 1.00 71.67  ?  619 PRO B N   1 
ATOM   9980  C CA  . PRO B 1 630 ? 147.552 172.062 117.160 1.00 71.67  ?  619 PRO B CA  1 
ATOM   9981  C C   . PRO B 1 630 ? 148.286 173.190 116.453 1.00 71.67  ?  619 PRO B C   1 
ATOM   9982  O O   . PRO B 1 630 ? 148.219 174.351 116.856 1.00 71.67  ?  619 PRO B O   1 
ATOM   9983  C CB  . PRO B 1 630 ? 146.082 171.998 116.737 1.00 71.67  ?  619 PRO B CB  1 
ATOM   9984  C CG  . PRO B 1 630 ? 145.358 171.596 117.958 1.00 71.67  ?  619 PRO B CG  1 
ATOM   9985  C CD  . PRO B 1 630 ? 146.094 172.202 119.104 1.00 71.67  ?  619 PRO B CD  1 
ATOM   9986  N N   . ILE B 1 631 ? 149.000 172.831 115.389 1.00 77.91  ?  620 ILE B N   1 
ATOM   9987  C CA  . ILE B 1 631 ? 149.762 173.803 114.613 1.00 77.91  ?  620 ILE B CA  1 
ATOM   9988  C C   . ILE B 1 631 ? 148.799 174.440 113.617 1.00 77.91  ?  620 ILE B C   1 
ATOM   9989  O O   . ILE B 1 631 ? 148.255 173.767 112.742 1.00 77.91  ?  620 ILE B O   1 
ATOM   9990  C CB  . ILE B 1 631 ? 150.959 173.165 113.910 1.00 77.91  ?  620 ILE B CB  1 
ATOM   9991  C CG1 . ILE B 1 631 ? 152.035 172.793 114.922 1.00 77.91  ?  620 ILE B CG1 1 
ATOM   9992  C CG2 . ILE B 1 631 ? 151.525 174.108 112.870 1.00 77.91  ?  620 ILE B CG2 1 
ATOM   9993  C CD1 . ILE B 1 631 ? 153.303 172.348 114.283 1.00 77.91  ?  620 ILE B CD1 1 
ATOM   9994  N N   . ASN B 1 632 ? 148.593 175.744 113.747 1.00 92.45  ?  621 ASN B N   1 
ATOM   9995  C CA  . ASN B 1 632 ? 147.737 176.458 112.811 1.00 92.45  ?  621 ASN B CA  1 
ATOM   9996  C C   . ASN B 1 632 ? 148.587 177.470 112.077 1.00 92.45  ?  621 ASN B C   1 
ATOM   9997  O O   . ASN B 1 632 ? 148.829 178.561 112.583 1.00 92.45  ?  621 ASN B O   1 
ATOM   9998  C CB  . ASN B 1 632 ? 146.600 177.160 113.544 1.00 92.45  ?  621 ASN B CB  1 
ATOM   9999  C CG  . ASN B 1 632 ? 145.678 177.907 112.605 1.00 92.45  ?  621 ASN B CG  1 
ATOM   10000 O OD1 . ASN B 1 632 ? 145.593 177.592 111.419 1.00 92.45  ?  621 ASN B OD1 1 
ATOM   10001 N ND2 . ASN B 1 632 ? 144.974 178.899 113.135 1.00 92.45  ?  621 ASN B ND2 1 
ATOM   10002 N N   . THR B 1 633 ? 149.052 177.114 110.887 1.00 101.34 ?  622 THR B N   1 
ATOM   10003 C CA  . THR B 1 633 ? 149.940 178.001 110.144 1.00 101.34 ?  622 THR B CA  1 
ATOM   10004 C C   . THR B 1 633 ? 149.197 178.753 109.043 1.00 101.34 ?  622 THR B C   1 
ATOM   10005 O O   . THR B 1 633 ? 149.808 179.221 108.084 1.00 101.34 ?  622 THR B O   1 
ATOM   10006 C CB  . THR B 1 633 ? 151.124 177.223 109.542 1.00 101.34 ?  622 THR B CB  1 
ATOM   10007 O OG1 . THR B 1 633 ? 152.027 178.138 108.909 1.00 101.34 ?  622 THR B OG1 1 
ATOM   10008 C CG2 . THR B 1 633 ? 150.634 176.206 108.522 1.00 101.34 ?  622 THR B CG2 1 
ATOM   10009 N N   . THR B 1 634 ? 147.884 178.883 109.185 1.00 108.02 ?  623 THR B N   1 
ATOM   10010 C CA  . THR B 1 634 ? 147.102 179.619 108.200 1.00 108.02 ?  623 THR B CA  1 
ATOM   10011 C C   . THR B 1 634 ? 147.612 181.045 108.090 1.00 108.02 ?  623 THR B C   1 
ATOM   10012 O O   . THR B 1 634 ? 147.505 181.669 107.036 1.00 108.02 ?  623 THR B O   1 
ATOM   10013 C CB  . THR B 1 634 ? 145.607 179.639 108.559 1.00 108.02 ?  623 THR B CB  1 
ATOM   10014 O OG1 . THR B 1 634 ? 144.879 180.327 107.535 1.00 108.02 ?  623 THR B OG1 1 
ATOM   10015 C CG2 . THR B 1 634 ? 145.388 180.343 109.888 1.00 108.02 ?  623 THR B CG2 1 
ATOM   10016 N N   . ASP B 1 635 ? 148.174 181.567 109.173 1.00 112.34 ?  624 ASP B N   1 
ATOM   10017 C CA  . ASP B 1 635 ? 148.736 182.908 109.142 1.00 112.34 ?  624 ASP B CA  1 
ATOM   10018 C C   . ASP B 1 635 ? 149.785 183.001 108.055 1.00 112.34 ?  624 ASP B C   1 
ATOM   10019 O O   . ASP B 1 635 ? 149.821 183.969 107.299 1.00 112.34 ?  624 ASP B O   1 
ATOM   10020 C CB  . ASP B 1 635 ? 149.363 183.246 110.489 1.00 112.34 ?  624 ASP B CB  1 
ATOM   10021 C CG  . ASP B 1 635 ? 150.236 184.480 110.429 1.00 112.34 ?  624 ASP B CG  1 
ATOM   10022 O OD1 . ASP B 1 635 ? 149.705 185.595 110.613 1.00 112.34 ?  624 ASP B OD1 1 
ATOM   10023 O OD2 . ASP B 1 635 ? 151.456 184.336 110.198 1.00 112.34 -1 624 ASP B OD2 1 
ATOM   10024 N N   . LEU B 1 636 ? 150.645 181.994 107.969 1.00 114.98 ?  625 LEU B N   1 
ATOM   10025 C CA  . LEU B 1 636 ? 151.665 181.984 106.933 1.00 114.98 ?  625 LEU B CA  1 
ATOM   10026 C C   . LEU B 1 636 ? 151.049 181.649 105.586 1.00 114.98 ?  625 LEU B C   1 
ATOM   10027 O O   . LEU B 1 636 ? 150.208 180.759 105.492 1.00 114.98 ?  625 LEU B O   1 
ATOM   10028 C CB  . LEU B 1 636 ? 152.782 180.995 107.272 1.00 114.98 ?  625 LEU B CB  1 
ATOM   10029 C CG  . LEU B 1 636 ? 153.743 181.378 108.400 1.00 114.98 ?  625 LEU B CG  1 
ATOM   10030 C CD1 . LEU B 1 636 ? 153.031 181.470 109.741 1.00 114.98 ?  625 LEU B CD1 1 
ATOM   10031 C CD2 . LEU B 1 636 ? 154.886 180.379 108.473 1.00 114.98 ?  625 LEU B CD2 1 
ATOM   10032 N N   . PRO B 1 637 ? 151.455 182.370 104.537 1.00 118.72 ?  626 PRO B N   1 
ATOM   10033 C CA  . PRO B 1 637 ? 150.929 182.131 103.188 1.00 118.72 ?  626 PRO B CA  1 
ATOM   10034 C C   . PRO B 1 637 ? 151.228 180.741 102.637 1.00 118.72 ?  626 PRO B C   1 
ATOM   10035 O O   . PRO B 1 637 ? 150.361 180.166 101.979 1.00 118.72 ?  626 PRO B O   1 
ATOM   10036 C CB  . PRO B 1 637 ? 151.667 183.174 102.351 1.00 118.72 ?  626 PRO B CB  1 
ATOM   10037 C CG  . PRO B 1 637 ? 151.940 184.285 103.301 1.00 118.72 ?  626 PRO B CG  1 
ATOM   10038 C CD  . PRO B 1 637 ? 152.204 183.632 104.627 1.00 118.72 ?  626 PRO B CD  1 
ATOM   10039 N N   . PHE B 1 638 ? 152.421 180.209 102.884 1.00 118.85 ?  627 PHE B N   1 
ATOM   10040 C CA  . PHE B 1 638 ? 152.793 178.916 102.299 1.00 118.85 ?  627 PHE B CA  1 
ATOM   10041 C C   . PHE B 1 638 ? 152.926 177.799 103.323 1.00 118.85 ?  627 PHE B C   1 
ATOM   10042 O O   . PHE B 1 638 ? 153.412 178.020 104.429 1.00 118.85 ?  627 PHE B O   1 
ATOM   10043 C CB  . PHE B 1 638 ? 154.096 179.045 101.514 1.00 118.85 ?  627 PHE B CB  1 
ATOM   10044 C CG  . PHE B 1 638 ? 155.247 179.553 102.330 1.00 118.85 ?  627 PHE B CG  1 
ATOM   10045 C CD1 . PHE B 1 638 ? 155.267 180.860 102.785 1.00 118.85 ?  627 PHE B CD1 1 
ATOM   10046 C CD2 . PHE B 1 638 ? 156.313 178.725 102.634 1.00 118.85 ?  627 PHE B CD2 1 
ATOM   10047 C CE1 . PHE B 1 638 ? 156.325 181.331 103.532 1.00 118.85 ?  627 PHE B CE1 1 
ATOM   10048 C CE2 . PHE B 1 638 ? 157.375 179.191 103.380 1.00 118.85 ?  627 PHE B CE2 1 
ATOM   10049 C CZ  . PHE B 1 638 ? 157.381 180.496 103.827 1.00 118.85 ?  627 PHE B CZ  1 
ATOM   10050 N N   . HIS B 1 639 ? 152.491 176.599 102.949 1.00 114.49 ?  628 HIS B N   1 
ATOM   10051 C CA  . HIS B 1 639 ? 152.570 175.460 103.855 1.00 114.49 ?  628 HIS B CA  1 
ATOM   10052 C C   . HIS B 1 639 ? 153.997 175.185 104.282 1.00 114.49 ?  628 HIS B C   1 
ATOM   10053 O O   . HIS B 1 639 ? 154.933 175.442 103.527 1.00 114.49 ?  628 HIS B O   1 
ATOM   10054 C CB  . HIS B 1 639 ? 151.990 174.211 103.194 1.00 114.49 ?  628 HIS B CB  1 
ATOM   10055 N N   . ILE B 1 640 ? 154.168 174.668 105.490 1.00 101.39 ?  629 ILE B N   1 
ATOM   10056 C CA  . ILE B 1 640 ? 155.496 174.317 105.958 1.00 101.39 ?  629 ILE B CA  1 
ATOM   10057 C C   . ILE B 1 640 ? 155.649 172.818 105.909 1.00 101.39 ?  629 ILE B C   1 
ATOM   10058 O O   . ILE B 1 640 ? 154.895 172.098 106.555 1.00 101.39 ?  629 ILE B O   1 
ATOM   10059 C CB  . ILE B 1 640 ? 155.744 174.789 107.400 1.00 101.39 ?  629 ILE B CB  1 
ATOM   10060 C CG1 . ILE B 1 640 ? 155.643 176.312 107.487 1.00 101.39 ?  629 ILE B CG1 1 
ATOM   10061 C CG2 . ILE B 1 640 ? 157.101 174.312 107.894 1.00 101.39 ?  629 ILE B CG2 1 
ATOM   10062 C CD1 . ILE B 1 640 ? 155.912 176.858 108.871 1.00 101.39 ?  629 ILE B CD1 1 
ATOM   10063 N N   . ASP B 1 641 ? 156.615 172.334 105.141 1.00 93.08  ?  630 ASP B N   1 
ATOM   10064 C CA  . ASP B 1 641 ? 156.865 170.909 105.126 1.00 93.08  ?  630 ASP B CA  1 
ATOM   10065 C C   . ASP B 1 641 ? 157.733 170.594 106.317 1.00 93.08  ?  630 ASP B C   1 
ATOM   10066 O O   . ASP B 1 641 ? 158.948 170.766 106.271 1.00 93.08  ?  630 ASP B O   1 
ATOM   10067 C CB  . ASP B 1 641 ? 157.540 170.474 103.830 1.00 93.08  ?  630 ASP B CB  1 
ATOM   10068 C CG  . ASP B 1 641 ? 156.636 170.627 102.627 1.00 93.08  ?  630 ASP B CG  1 
ATOM   10069 O OD1 . ASP B 1 641 ? 155.494 171.104 102.800 1.00 93.08  ?  630 ASP B OD1 1 
ATOM   10070 O OD2 . ASP B 1 641 ? 157.066 170.268 101.511 1.00 93.08  -1 630 ASP B OD2 1 
ATOM   10071 N N   . TRP B 1 642 ? 157.114 170.128 107.393 1.00 83.50  ?  631 TRP B N   1 
ATOM   10072 C CA  . TRP B 1 642 ? 157.857 169.851 108.613 1.00 83.50  ?  631 TRP B CA  1 
ATOM   10073 C C   . TRP B 1 642 ? 158.865 168.744 108.407 1.00 83.50  ?  631 TRP B C   1 
ATOM   10074 O O   . TRP B 1 642 ? 159.806 168.603 109.181 1.00 83.50  ?  631 TRP B O   1 
ATOM   10075 C CB  . TRP B 1 642 ? 156.894 169.497 109.739 1.00 83.50  ?  631 TRP B CB  1 
ATOM   10076 C CG  . TRP B 1 642 ? 156.110 170.667 110.220 1.00 83.50  ?  631 TRP B CG  1 
ATOM   10077 C CD1 . TRP B 1 642 ? 154.779 170.886 110.051 1.00 83.50  ?  631 TRP B CD1 1 
ATOM   10078 C CD2 . TRP B 1 642 ? 156.615 171.793 110.942 1.00 83.50  ?  631 TRP B CD2 1 
ATOM   10079 N NE1 . TRP B 1 642 ? 154.419 172.076 110.630 1.00 83.50  ?  631 TRP B NE1 1 
ATOM   10080 C CE2 . TRP B 1 642 ? 155.529 172.653 111.184 1.00 83.50  ?  631 TRP B CE2 1 
ATOM   10081 C CE3 . TRP B 1 642 ? 157.881 172.155 111.411 1.00 83.50  ?  631 TRP B CE3 1 
ATOM   10082 C CZ2 . TRP B 1 642 ? 155.670 173.854 111.872 1.00 83.50  ?  631 TRP B CZ2 1 
ATOM   10083 C CZ3 . TRP B 1 642 ? 158.016 173.346 112.092 1.00 83.50  ?  631 TRP B CZ3 1 
ATOM   10084 C CH2 . TRP B 1 642 ? 156.919 174.181 112.317 1.00 83.50  ?  631 TRP B CH2 1 
ATOM   10085 N N   . ASN B 1 643 ? 158.681 167.959 107.358 1.00 82.63  ?  632 ASN B N   1 
ATOM   10086 C CA  . ASN B 1 643 ? 159.627 166.894 107.062 1.00 82.63  ?  632 ASN B CA  1 
ATOM   10087 C C   . ASN B 1 643 ? 160.686 167.378 106.084 1.00 82.63  ?  632 ASN B C   1 
ATOM   10088 O O   . ASN B 1 643 ? 161.490 166.588 105.600 1.00 82.63  ?  632 ASN B O   1 
ATOM   10089 C CB  . ASN B 1 643 ? 158.899 165.650 106.550 1.00 82.63  ?  632 ASN B CB  1 
ATOM   10090 C CG  . ASN B 1 643 ? 158.080 164.973 107.631 1.00 82.63  ?  632 ASN B CG  1 
ATOM   10091 O OD1 . ASN B 1 643 ? 158.311 165.184 108.821 1.00 82.63  ?  632 ASN B OD1 1 
ATOM   10092 N ND2 . ASN B 1 643 ? 157.123 164.150 107.225 1.00 82.63  ?  632 ASN B ND2 1 
ATOM   10093 N N   . ASP B 1 644 ? 160.696 168.674 105.802 1.00 92.59  ?  633 ASP B N   1 
ATOM   10094 C CA  . ASP B 1 644 ? 161.721 169.240 104.934 1.00 92.59  ?  633 ASP B CA  1 
ATOM   10095 C C   . ASP B 1 644 ? 162.514 170.273 105.715 1.00 92.59  ?  633 ASP B C   1 
ATOM   10096 O O   . ASP B 1 644 ? 162.046 170.761 106.739 1.00 92.59  ?  633 ASP B O   1 
ATOM   10097 C CB  . ASP B 1 644 ? 161.091 169.884 103.707 1.00 92.59  ?  633 ASP B CB  1 
ATOM   10098 C CG  . ASP B 1 644 ? 162.109 170.219 102.639 1.00 92.59  ?  633 ASP B CG  1 
ATOM   10099 O OD1 . ASP B 1 644 ? 161.753 170.940 101.684 1.00 92.59  ?  633 ASP B OD1 1 
ATOM   10100 O OD2 . ASP B 1 644 ? 163.266 169.761 102.753 1.00 92.59  -1 633 ASP B OD2 1 
ATOM   10101 N N   . ASP B 1 645 ? 163.704 170.622 105.241 1.00 98.09  ?  634 ASP B N   1 
ATOM   10102 C CA  . ASP B 1 645 ? 164.563 171.564 105.964 1.00 98.09  ?  634 ASP B CA  1 
ATOM   10103 C C   . ASP B 1 645 ? 163.906 172.917 106.223 1.00 98.09  ?  634 ASP B C   1 
ATOM   10104 O O   . ASP B 1 645 ? 163.231 173.459 105.351 1.00 98.09  ?  634 ASP B O   1 
ATOM   10105 C CB  . ASP B 1 645 ? 165.873 171.763 105.203 1.00 98.09  ?  634 ASP B CB  1 
ATOM   10106 C CG  . ASP B 1 645 ? 166.608 170.463 104.964 1.00 98.09  ?  634 ASP B CG  1 
ATOM   10107 O OD1 . ASP B 1 645 ? 166.181 169.429 105.520 1.00 98.09  ?  634 ASP B OD1 1 
ATOM   10108 O OD2 . ASP B 1 645 ? 167.612 170.474 104.222 1.00 98.09  -1 634 ASP B OD2 1 
ATOM   10109 N N   . LEU B 1 646 ? 164.113 173.464 107.418 1.00 103.13 ?  635 LEU B N   1 
ATOM   10110 C CA  . LEU B 1 646 ? 163.509 174.747 107.781 1.00 103.13 ?  635 LEU B CA  1 
ATOM   10111 C C   . LEU B 1 646 ? 164.510 175.894 107.696 1.00 103.13 ?  635 LEU B C   1 
ATOM   10112 O O   . LEU B 1 646 ? 165.717 175.664 107.665 1.00 103.13 ?  635 LEU B O   1 
ATOM   10113 C CB  . LEU B 1 646 ? 162.908 174.682 109.187 1.00 103.13 ?  635 LEU B CB  1 
ATOM   10114 C CG  . LEU B 1 646 ? 161.614 173.898 109.407 1.00 103.13 ?  635 LEU B CG  1 
ATOM   10115 C CD1 . LEU B 1 646 ? 161.861 172.401 109.329 1.00 103.13 ?  635 LEU B CD1 1 
ATOM   10116 C CD2 . LEU B 1 646 ? 161.031 174.260 110.763 1.00 103.13 ?  635 LEU B CD2 1 
ATOM   10117 N N   . PRO B 1 647 ? 164.013 177.139 107.664 1.00 110.87 ?  636 PRO B N   1 
ATOM   10118 C CA  . PRO B 1 647 ? 164.906 178.296 107.514 1.00 110.87 ?  636 PRO B CA  1 
ATOM   10119 C C   . PRO B 1 647 ? 165.801 178.573 108.712 1.00 110.87 ?  636 PRO B C   1 
ATOM   10120 O O   . PRO B 1 647 ? 165.421 178.256 109.835 1.00 110.87 ?  636 PRO B O   1 
ATOM   10121 C CB  . PRO B 1 647 ? 163.923 179.461 107.344 1.00 110.87 ?  636 PRO B CB  1 
ATOM   10122 C CG  . PRO B 1 647 ? 162.683 179.009 108.033 1.00 110.87 ?  636 PRO B CG  1 
ATOM   10123 C CD  . PRO B 1 647 ? 162.599 177.541 107.740 1.00 110.87 ?  636 PRO B CD  1 
ATOM   10124 N N   . LEU B 1 648 ? 166.976 179.152 108.477 1.00 114.34 ?  637 LEU B N   1 
ATOM   10125 C CA  . LEU B 1 648 ? 167.874 179.534 109.573 1.00 114.34 ?  637 LEU B CA  1 
ATOM   10126 C C   . LEU B 1 648 ? 168.276 178.380 110.475 1.00 114.34 ?  637 LEU B C   1 
ATOM   10127 O O   . LEU B 1 648 ? 168.384 178.552 111.688 1.00 114.34 ?  637 LEU B O   1 
ATOM   10128 C CB  . LEU B 1 648 ? 167.259 180.665 110.412 1.00 114.34 ?  637 LEU B CB  1 
ATOM   10129 C CG  . LEU B 1 648 ? 167.209 182.051 109.763 1.00 114.34 ?  637 LEU B CG  1 
ATOM   10130 C CD1 . LEU B 1 648 ? 168.579 182.448 109.236 1.00 114.34 ?  637 LEU B CD1 1 
ATOM   10131 C CD2 . LEU B 1 648 ? 166.171 182.107 108.654 1.00 114.34 ?  637 LEU B CD2 1 
ATOM   10132 N N   . ASN B 1 649 ? 168.499 177.209 109.896 1.00 109.36 ?  638 ASN B N   1 
ATOM   10133 C CA  . ASN B 1 649 ? 168.979 176.069 110.679 1.00 109.36 ?  638 ASN B CA  1 
ATOM   10134 C C   . ASN B 1 649 ? 168.092 175.680 111.856 1.00 109.36 ?  638 ASN B C   1 
ATOM   10135 O O   . ASN B 1 649 ? 168.601 175.380 112.934 1.00 109.36 ?  638 ASN B O   1 
ATOM   10136 C CB  . ASN B 1 649 ? 170.394 176.354 111.190 1.00 109.36 ?  638 ASN B CB  1 
ATOM   10137 C CG  . ASN B 1 649 ? 171.327 176.820 110.091 1.00 109.36 ?  638 ASN B CG  1 
ATOM   10138 O OD1 . ASN B 1 649 ? 170.953 176.865 108.921 1.00 109.36 ?  638 ASN B OD1 1 
ATOM   10139 N ND2 . ASN B 1 649 ? 172.552 177.170 110.466 1.00 109.36 ?  638 ASN B ND2 1 
ATOM   10140 N N   . ILE B 1 650 ? 166.779 175.680 111.667 1.00 103.17 ?  639 ILE B N   1 
ATOM   10141 C CA  . ILE B 1 650 ? 165.887 175.218 112.727 1.00 103.17 ?  639 ILE B CA  1 
ATOM   10142 C C   . ILE B 1 650 ? 165.757 173.710 112.578 1.00 103.17 ?  639 ILE B C   1 
ATOM   10143 O O   . ILE B 1 650 ? 165.326 173.236 111.531 1.00 103.17 ?  639 ILE B O   1 
ATOM   10144 C CB  . ILE B 1 650 ? 164.525 175.921 112.666 1.00 103.17 ?  639 ILE B CB  1 
ATOM   10145 C CG1 . ILE B 1 650 ? 164.719 177.435 112.738 1.00 103.17 ?  639 ILE B CG1 1 
ATOM   10146 C CG2 . ILE B 1 650 ? 163.631 175.442 113.794 1.00 103.17 ?  639 ILE B CG2 1 
ATOM   10147 C CD1 . ILE B 1 650 ? 163.433 178.225 112.668 1.00 103.17 ?  639 ILE B CD1 1 
ATOM   10148 N N   . GLU B 1 651 ? 166.125 172.949 113.604 1.00 97.06  ?  640 GLU B N   1 
ATOM   10149 C CA  . GLU B 1 651 ? 166.130 171.499 113.493 1.00 97.06  ?  640 GLU B CA  1 
ATOM   10150 C C   . GLU B 1 651 ? 164.891 170.912 114.149 1.00 97.06  ?  640 GLU B C   1 
ATOM   10151 O O   . GLU B 1 651 ? 164.593 171.181 115.315 1.00 97.06  ?  640 GLU B O   1 
ATOM   10152 C CB  . GLU B 1 651 ? 167.390 170.897 114.122 1.00 97.06  ?  640 GLU B CB  1 
ATOM   10153 C CG  . GLU B 1 651 ? 168.656 171.157 113.321 1.00 97.06  ?  640 GLU B CG  1 
ATOM   10154 C CD  . GLU B 1 651 ? 169.918 170.845 114.100 1.00 97.06  ?  640 GLU B CD  1 
ATOM   10155 O OE1 . GLU B 1 651 ? 169.906 170.991 115.339 1.00 97.06  ?  640 GLU B OE1 1 
ATOM   10156 O OE2 . GLU B 1 651 ? 170.922 170.453 113.470 1.00 97.06  -1 640 GLU B OE2 1 
ATOM   10157 N N   . VAL B 1 652 ? 164.174 170.103 113.374 1.00 85.02  ?  641 VAL B N   1 
ATOM   10158 C CA  . VAL B 1 652 ? 162.992 169.376 113.830 1.00 85.02  ?  641 VAL B CA  1 
ATOM   10159 C C   . VAL B 1 652 ? 163.179 167.923 113.407 1.00 85.02  ?  641 VAL B C   1 
ATOM   10160 O O   . VAL B 1 652 ? 163.697 167.670 112.311 1.00 85.02  ?  641 VAL B O   1 
ATOM   10161 C CB  . VAL B 1 652 ? 161.699 169.966 113.240 1.00 85.02  ?  641 VAL B CB  1 
ATOM   10162 C CG1 . VAL B 1 652 ? 160.508 169.621 114.106 1.00 85.02  ?  641 VAL B CG1 1 
ATOM   10163 C CG2 . VAL B 1 652 ? 161.815 171.462 113.075 1.00 85.02  ?  641 VAL B CG2 1 
ATOM   10164 N N   . PRO B 1 653 ? 162.799 166.978 114.285 1.00 79.16  ?  642 PRO B N   1 
ATOM   10165 C CA  . PRO B 1 653 ? 162.896 165.583 113.872 1.00 79.16  ?  642 PRO B CA  1 
ATOM   10166 C C   . PRO B 1 653 ? 161.933 165.305 112.742 1.00 79.16  ?  642 PRO B C   1 
ATOM   10167 O O   . PRO B 1 653 ? 160.751 165.614 112.850 1.00 79.16  ?  642 PRO B O   1 
ATOM   10168 C CB  . PRO B 1 653 ? 162.480 164.815 115.128 1.00 79.16  ?  642 PRO B CB  1 
ATOM   10169 C CG  . PRO B 1 653 ? 162.662 165.768 116.255 1.00 79.16  ?  642 PRO B CG  1 
ATOM   10170 C CD  . PRO B 1 653 ? 162.316 167.099 115.672 1.00 79.16  ?  642 PRO B CD  1 
ATOM   10171 N N   . LYS B 1 654 ? 162.439 164.735 111.661 1.00 77.12  ?  643 LYS B N   1 
ATOM   10172 C CA  . LYS B 1 654 ? 161.599 164.428 110.523 1.00 77.12  ?  643 LYS B CA  1 
ATOM   10173 C C   . LYS B 1 654 ? 161.027 163.033 110.645 1.00 77.12  ?  643 LYS B C   1 
ATOM   10174 O O   . LYS B 1 654 ? 161.741 162.092 110.971 1.00 77.12  ?  643 LYS B O   1 
ATOM   10175 C CB  . LYS B 1 654 ? 162.402 164.562 109.238 1.00 77.12  ?  643 LYS B CB  1 
ATOM   10176 C CG  . LYS B 1 654 ? 162.890 165.970 108.960 1.00 77.12  ?  643 LYS B CG  1 
ATOM   10177 C CD  . LYS B 1 654 ? 163.674 166.015 107.664 1.00 77.12  ?  643 LYS B CD  1 
ATOM   10178 C CE  . LYS B 1 654 ? 164.042 167.437 107.286 1.00 77.12  ?  643 LYS B CE  1 
ATOM   10179 N NZ  . LYS B 1 654 ? 164.595 167.484 105.906 1.00 77.12  1  643 LYS B NZ  1 
ATOM   10180 N N   . ILE B 1 655 ? 159.734 162.899 110.392 1.00 65.08  ?  644 ILE B N   1 
ATOM   10181 C CA  . ILE B 1 655 ? 159.093 161.595 110.461 1.00 65.08  ?  644 ILE B CA  1 
ATOM   10182 C C   . ILE B 1 655 ? 158.743 161.086 109.068 1.00 65.08  ?  644 ILE B C   1 
ATOM   10183 O O   . ILE B 1 655 ? 158.467 161.868 108.165 1.00 65.08  ?  644 ILE B O   1 
ATOM   10184 C CB  . ILE B 1 655 ? 157.843 161.634 111.367 1.00 65.08  ?  644 ILE B CB  1 
ATOM   10185 C CG1 . ILE B 1 655 ? 156.891 162.752 110.946 1.00 65.08  ?  644 ILE B CG1 1 
ATOM   10186 C CG2 . ILE B 1 655 ? 158.248 161.824 112.819 1.00 65.08  ?  644 ILE B CG2 1 
ATOM   10187 C CD1 . ILE B 1 655 ? 155.890 162.347 109.890 1.00 65.08  ?  644 ILE B CD1 1 
ATOM   10188 N N   . SER B 1 656 ? 158.771 159.774 108.886 1.00 59.07  ?  645 SER B N   1 
ATOM   10189 C CA  . SER B 1 656 ? 158.420 159.188 107.595 1.00 59.07  ?  645 SER B CA  1 
ATOM   10190 C C   . SER B 1 656 ? 157.005 158.627 107.592 1.00 59.07  ?  645 SER B C   1 
ATOM   10191 O O   . SER B 1 656 ? 156.450 158.353 106.538 1.00 59.07  ?  645 SER B O   1 
ATOM   10192 C CB  . SER B 1 656 ? 159.415 158.091 107.231 1.00 59.07  ?  645 SER B CB  1 
ATOM   10193 O OG  . SER B 1 656 ? 160.728 158.608 107.140 1.00 59.07  ?  645 SER B OG  1 
ATOM   10194 N N   . LEU B 1 657 ? 156.421 158.458 108.768 1.00 52.59  ?  646 LEU B N   1 
ATOM   10195 C CA  . LEU B 1 657 ? 155.078 157.919 108.864 1.00 52.59  ?  646 LEU B CA  1 
ATOM   10196 C C   . LEU B 1 657 ? 154.037 158.912 108.430 1.00 52.59  ?  646 LEU B C   1 
ATOM   10197 O O   . LEU B 1 657 ? 154.047 160.052 108.866 1.00 52.59  ?  646 LEU B O   1 
ATOM   10198 C CB  . LEU B 1 657 ? 154.786 157.494 110.303 1.00 52.59  ?  646 LEU B CB  1 
ATOM   10199 C CG  . LEU B 1 657 ? 153.462 156.782 110.559 1.00 52.59  ?  646 LEU B CG  1 
ATOM   10200 C CD1 . LEU B 1 657 ? 153.452 155.463 109.808 1.00 52.59  ?  646 LEU B CD1 1 
ATOM   10201 C CD2 . LEU B 1 657 ? 153.281 156.552 112.049 1.00 52.59  ?  646 LEU B CD2 1 
ATOM   10202 N N   . HIS B 1 658 ? 153.131 158.491 107.565 1.00 53.21  ?  647 HIS B N   1 
ATOM   10203 C CA  . HIS B 1 658 ? 152.030 159.357 107.182 1.00 53.21  ?  647 HIS B CA  1 
ATOM   10204 C C   . HIS B 1 658 ? 150.719 158.648 107.455 1.00 53.21  ?  647 HIS B C   1 
ATOM   10205 O O   . HIS B 1 658 ? 149.670 159.280 107.490 1.00 53.21  ?  647 HIS B O   1 
ATOM   10206 C CB  . HIS B 1 658 ? 152.124 159.788 105.715 1.00 53.21  ?  647 HIS B CB  1 
ATOM   10207 C CG  . HIS B 1 658 ? 152.149 158.652 104.741 1.00 53.21  ?  647 HIS B CG  1 
ATOM   10208 N ND1 . HIS B 1 658 ? 151.023 157.937 104.399 1.00 53.21  ?  647 HIS B ND1 1 
ATOM   10209 C CD2 . HIS B 1 658 ? 153.162 158.127 104.013 1.00 53.21  ?  647 HIS B CD2 1 
ATOM   10210 C CE1 . HIS B 1 658 ? 151.343 157.009 103.517 1.00 53.21  ?  647 HIS B CE1 1 
ATOM   10211 N NE2 . HIS B 1 658 ? 152.635 157.104 103.264 1.00 53.21  ?  647 HIS B NE2 1 
ATOM   10212 N N   . SER B 1 659 ? 150.766 157.333 107.640 1.00 48.44  ?  648 SER B N   1 
ATOM   10213 C CA  . SER B 1 659 ? 149.528 156.593 107.821 1.00 48.44  ?  648 SER B CA  1 
ATOM   10214 C C   . SER B 1 659 ? 149.763 155.514 108.859 1.00 48.44  ?  648 SER B C   1 
ATOM   10215 O O   . SER B 1 659 ? 150.679 154.704 108.710 1.00 48.44  ?  648 SER B O   1 
ATOM   10216 C CB  . SER B 1 659 ? 149.057 155.969 106.509 1.00 48.44  ?  648 SER B CB  1 
ATOM   10217 O OG  . SER B 1 659 ? 148.907 156.951 105.502 1.00 48.44  ?  648 SER B OG  1 
ATOM   10218 N N   . LEU B 1 660 ? 148.946 155.506 109.902 1.00 42.90  ?  649 LEU B N   1 
ATOM   10219 C CA  . LEU B 1 660 ? 149.051 154.518 110.965 1.00 42.90  ?  649 LEU B CA  1 
ATOM   10220 C C   . LEU B 1 660 ? 147.762 153.716 110.999 1.00 42.90  ?  649 LEU B C   1 
ATOM   10221 O O   . LEU B 1 660 ? 146.686 154.275 111.232 1.00 42.90  ?  649 LEU B O   1 
ATOM   10222 C CB  . LEU B 1 660 ? 149.312 155.184 112.317 1.00 42.90  ?  649 LEU B CB  1 
ATOM   10223 C CG  . LEU B 1 660 ? 149.203 154.263 113.525 1.00 42.90  ?  649 LEU B CG  1 
ATOM   10224 C CD1 . LEU B 1 660 ? 150.530 153.615 113.824 1.00 42.90  ?  649 LEU B CD1 1 
ATOM   10225 C CD2 . LEU B 1 660 ? 148.692 155.017 114.725 1.00 42.90  ?  649 LEU B CD2 1 
ATOM   10226 N N   . ILE B 1 661 ? 147.868 152.416 110.754 1.00 39.77  ?  650 ILE B N   1 
ATOM   10227 C CA  . ILE B 1 661 ? 146.730 151.508 110.801 1.00 39.77  ?  650 ILE B CA  1 
ATOM   10228 C C   . ILE B 1 661 ? 146.798 150.744 112.111 1.00 39.77  ?  650 ILE B C   1 
ATOM   10229 O O   . ILE B 1 661 ? 147.866 150.257 112.500 1.00 39.77  ?  650 ILE B O   1 
ATOM   10230 C CB  . ILE B 1 661 ? 146.720 150.552 109.598 1.00 39.77  ?  650 ILE B CB  1 
ATOM   10231 C CG1 . ILE B 1 661 ? 146.961 151.327 108.308 1.00 39.77  ?  650 ILE B CG1 1 
ATOM   10232 C CG2 . ILE B 1 661 ? 145.411 149.799 109.526 1.00 39.77  ?  650 ILE B CG2 1 
ATOM   10233 C CD1 . ILE B 1 661 ? 146.686 150.537 107.083 1.00 39.77  ?  650 ILE B CD1 1 
ATOM   10234 N N   . LEU B 1 662 ? 145.670 150.652 112.802 1.00 40.17  ?  651 LEU B N   1 
ATOM   10235 C CA  . LEU B 1 662 ? 145.567 149.924 114.058 1.00 40.17  ?  651 LEU B CA  1 
ATOM   10236 C C   . LEU B 1 662 ? 144.626 148.748 113.846 1.00 40.17  ?  651 LEU B C   1 
ATOM   10237 O O   . LEU B 1 662 ? 143.432 148.939 113.609 1.00 40.17  ?  651 LEU B O   1 
ATOM   10238 C CB  . LEU B 1 662 ? 145.068 150.833 115.177 1.00 40.17  ?  651 LEU B CB  1 
ATOM   10239 C CG  . LEU B 1 662 ? 145.951 152.007 115.593 1.00 40.17  ?  651 LEU B CG  1 
ATOM   10240 C CD1 . LEU B 1 662 ? 145.153 152.950 116.455 1.00 40.17  ?  651 LEU B CD1 1 
ATOM   10241 C CD2 . LEU B 1 662 ? 147.169 151.522 116.335 1.00 40.17  ?  651 LEU B CD2 1 
ATOM   10242 N N   . ASP B 1 663 ? 145.162 147.535 113.928 1.00 42.32  ?  652 ASP B N   1 
ATOM   10243 C CA  . ASP B 1 663 ? 144.376 146.326 113.696 1.00 42.32  ?  652 ASP B CA  1 
ATOM   10244 C C   . ASP B 1 663 ? 143.684 145.943 114.996 1.00 42.32  ?  652 ASP B C   1 
ATOM   10245 O O   . ASP B 1 663 ? 144.240 145.223 115.825 1.00 42.32  ?  652 ASP B O   1 
ATOM   10246 C CB  . ASP B 1 663 ? 145.261 145.202 113.182 1.00 42.32  ?  652 ASP B CB  1 
ATOM   10247 C CG  . ASP B 1 663 ? 144.501 143.912 112.985 1.00 42.32  ?  652 ASP B CG  1 
ATOM   10248 O OD1 . ASP B 1 663 ? 143.337 143.970 112.542 1.00 42.32  ?  652 ASP B OD1 1 
ATOM   10249 O OD2 . ASP B 1 663 ? 145.067 142.836 113.264 1.00 42.32  -1 652 ASP B OD2 1 
ATOM   10250 N N   . PHE B 1 664 ? 142.447 146.371 115.168 1.00 40.51  ?  653 PHE B N   1 
ATOM   10251 C CA  . PHE B 1 664 ? 141.698 146.107 116.388 1.00 40.51  ?  653 PHE B CA  1 
ATOM   10252 C C   . PHE B 1 664 ? 140.784 144.893 116.388 1.00 40.51  ?  653 PHE B C   1 
ATOM   10253 O O   . PHE B 1 664 ? 139.846 144.845 117.142 1.00 40.51  ?  653 PHE B O   1 
ATOM   10254 C CB  . PHE B 1 664 ? 140.866 147.334 116.731 1.00 40.51  ?  653 PHE B CB  1 
ATOM   10255 C CG  . PHE B 1 664 ? 141.576 148.323 117.586 1.00 40.51  ?  653 PHE B CG  1 
ATOM   10256 C CD1 . PHE B 1 664 ? 142.939 148.427 117.542 1.00 40.51  ?  653 PHE B CD1 1 
ATOM   10257 C CD2 . PHE B 1 664 ? 140.875 149.163 118.425 1.00 40.51  ?  653 PHE B CD2 1 
ATOM   10258 C CE1 . PHE B 1 664 ? 143.605 149.329 118.326 1.00 40.51  ?  653 PHE B CE1 1 
ATOM   10259 C CE2 . PHE B 1 664 ? 141.532 150.083 119.211 1.00 40.51  ?  653 PHE B CE2 1 
ATOM   10260 C CZ  . PHE B 1 664 ? 142.905 150.165 119.159 1.00 40.51  ?  653 PHE B CZ  1 
ATOM   10261 N N   . SER B 1 665 ? 141.060 143.915 115.550 1.00 41.07  ?  654 SER B N   1 
ATOM   10262 C CA  . SER B 1 665 ? 140.239 142.732 115.480 1.00 41.07  ?  654 SER B CA  1 
ATOM   10263 C C   . SER B 1 665 ? 140.201 141.938 116.783 1.00 41.07  ?  654 SER B C   1 
ATOM   10264 O O   . SER B 1 665 ? 139.158 141.515 117.206 1.00 41.07  ?  654 SER B O   1 
ATOM   10265 C CB  . SER B 1 665 ? 140.681 141.850 114.332 1.00 41.07  ?  654 SER B CB  1 
ATOM   10266 O OG  . SER B 1 665 ? 141.964 141.353 114.563 1.00 41.07  ?  654 SER B OG  1 
ATOM   10267 N N   . ALA B 1 666 ? 141.339 141.806 117.434 1.00 39.88  ?  655 ALA B N   1 
ATOM   10268 C CA  . ALA B 1 666 ? 141.463 141.093 118.682 1.00 39.88  ?  655 ALA B CA  1 
ATOM   10269 C C   . ALA B 1 666 ? 141.187 141.959 119.901 1.00 39.88  ?  655 ALA B C   1 
ATOM   10270 O O   . ALA B 1 666 ? 141.290 141.498 121.005 1.00 39.88  ?  655 ALA B O   1 
ATOM   10271 C CB  . ALA B 1 666 ? 142.832 140.455 118.776 1.00 39.88  ?  655 ALA B CB  1 
ATOM   10272 N N   . VAL B 1 667 ? 140.825 143.211 119.699 1.00 41.27  ?  656 VAL B N   1 
ATOM   10273 C CA  . VAL B 1 667 ? 140.511 144.096 120.819 1.00 41.27  ?  656 VAL B CA  1 
ATOM   10274 C C   . VAL B 1 667 ? 139.019 143.933 121.098 1.00 41.27  ?  656 VAL B C   1 
ATOM   10275 O O   . VAL B 1 667 ? 138.178 144.510 120.412 1.00 41.27  ?  656 VAL B O   1 
ATOM   10276 C CB  . VAL B 1 667 ? 140.882 145.551 120.527 1.00 41.27  ?  656 VAL B CB  1 
ATOM   10277 C CG1 . VAL B 1 667 ? 140.405 146.456 121.641 1.00 41.27  ?  656 VAL B CG1 1 
ATOM   10278 C CG2 . VAL B 1 667 ? 142.377 145.685 120.351 1.00 41.27  ?  656 VAL B CG2 1 
ATOM   10279 N N   . SER B 1 668 ? 138.692 143.131 122.110 1.00 43.23  ?  657 SER B N   1 
ATOM   10280 C CA  . SER B 1 668 ? 137.303 142.786 122.382 1.00 43.23  ?  657 SER B CA  1 
ATOM   10281 C C   . SER B 1 668 ? 136.535 143.967 122.964 1.00 43.23  ?  657 SER B C   1 
ATOM   10282 O O   . SER B 1 668 ? 135.431 144.284 122.516 1.00 43.23  ?  657 SER B O   1 
ATOM   10283 C CB  . SER B 1 668 ? 137.241 141.587 123.327 1.00 43.23  ?  657 SER B CB  1 
ATOM   10284 O OG  . SER B 1 668 ? 138.148 140.582 122.917 1.00 43.23  ?  657 SER B OG  1 
ATOM   10285 N N   . PHE B 1 669 ? 137.099 144.625 123.970 1.00 41.94  ?  658 PHE B N   1 
ATOM   10286 C CA  . PHE B 1 669 ? 136.431 145.737 124.624 1.00 41.94  ?  658 PHE B CA  1 
ATOM   10287 C C   . PHE B 1 669 ? 137.438 146.822 124.973 1.00 41.94  ?  658 PHE B C   1 
ATOM   10288 O O   . PHE B 1 669 ? 138.653 146.619 124.935 1.00 41.94  ?  658 PHE B O   1 
ATOM   10289 C CB  . PHE B 1 669 ? 135.671 145.282 125.882 1.00 41.94  ?  658 PHE B CB  1 
ATOM   10290 C CG  . PHE B 1 669 ? 136.543 144.677 126.952 1.00 41.94  ?  658 PHE B CG  1 
ATOM   10291 C CD1 . PHE B 1 669 ? 137.222 145.476 127.854 1.00 41.94  ?  658 PHE B CD1 1 
ATOM   10292 C CD2 . PHE B 1 669 ? 136.650 143.307 127.077 1.00 41.94  ?  658 PHE B CD2 1 
ATOM   10293 C CE1 . PHE B 1 669 ? 138.007 144.926 128.837 1.00 41.94  ?  658 PHE B CE1 1 
ATOM   10294 C CE2 . PHE B 1 669 ? 137.431 142.753 128.062 1.00 41.94  ?  658 PHE B CE2 1 
ATOM   10295 C CZ  . PHE B 1 669 ? 138.109 143.564 128.943 1.00 41.94  ?  658 PHE B CZ  1 
ATOM   10296 N N   . LEU B 1 670 ? 136.898 147.992 125.299 1.00 42.93  ?  659 LEU B N   1 
ATOM   10297 C CA  . LEU B 1 670 ? 137.639 149.099 125.879 1.00 42.93  ?  659 LEU B CA  1 
ATOM   10298 C C   . LEU B 1 670 ? 136.918 149.543 127.142 1.00 42.93  ?  659 LEU B C   1 
ATOM   10299 O O   . LEU B 1 670 ? 135.760 149.195 127.369 1.00 42.93  ?  659 LEU B O   1 
ATOM   10300 C CB  . LEU B 1 670 ? 137.754 150.284 124.912 1.00 42.93  ?  659 LEU B CB  1 
ATOM   10301 C CG  . LEU B 1 670 ? 138.453 150.123 123.565 1.00 42.93  ?  659 LEU B CG  1 
ATOM   10302 C CD1 . LEU B 1 670 ? 138.118 151.298 122.684 1.00 42.93  ?  659 LEU B CD1 1 
ATOM   10303 C CD2 . LEU B 1 670 ? 139.947 150.015 123.738 1.00 42.93  ?  659 LEU B CD2 1 
ATOM   10304 N N   . ASP B 1 671 ? 137.616 150.255 128.003 1.00 44.51  ?  660 ASP B N   1 
ATOM   10305 C CA  . ASP B 1 671 ? 136.987 150.780 129.196 1.00 44.51  ?  660 ASP B CA  1 
ATOM   10306 C C   . ASP B 1 671 ? 137.245 152.269 129.175 1.00 44.51  ?  660 ASP B C   1 
ATOM   10307 O O   . ASP B 1 671 ? 137.819 152.776 128.221 1.00 44.51  ?  660 ASP B O   1 
ATOM   10308 C CB  . ASP B 1 671 ? 137.547 150.109 130.446 1.00 44.51  ?  660 ASP B CB  1 
ATOM   10309 C CG  . ASP B 1 671 ? 139.022 150.397 130.666 1.00 44.51  ?  660 ASP B CG  1 
ATOM   10310 O OD1 . ASP B 1 671 ? 139.518 150.101 131.770 1.00 44.51  ?  660 ASP B OD1 1 
ATOM   10311 O OD2 . ASP B 1 671 ? 139.692 150.916 129.751 1.00 44.51  -1 660 ASP B OD2 1 
ATOM   10312 N N   . VAL B 1 672 ? 136.805 152.981 130.199 1.00 45.25  ?  661 VAL B N   1 
ATOM   10313 C CA  . VAL B 1 672 ? 136.967 154.428 130.209 1.00 45.25  ?  661 VAL B CA  1 
ATOM   10314 C C   . VAL B 1 672 ? 138.441 154.821 130.161 1.00 45.25  ?  661 VAL B C   1 
ATOM   10315 O O   . VAL B 1 672 ? 138.820 155.719 129.420 1.00 45.25  ?  661 VAL B O   1 
ATOM   10316 C CB  . VAL B 1 672 ? 136.270 155.073 131.427 1.00 45.25  ?  661 VAL B CB  1 
ATOM   10317 C CG1 . VAL B 1 672 ? 136.504 156.572 131.435 1.00 45.25  ?  661 VAL B CG1 1 
ATOM   10318 C CG2 . VAL B 1 672 ? 134.782 154.778 131.389 1.00 45.25  ?  661 VAL B CG2 1 
ATOM   10319 N N   . SER B 1 673 ? 139.275 154.136 130.925 1.00 45.50  ?  662 SER B N   1 
ATOM   10320 C CA  . SER B 1 673 ? 140.690 154.465 130.967 1.00 45.50  ?  662 SER B CA  1 
ATOM   10321 C C   . SER B 1 673 ? 141.325 154.304 129.600 1.00 45.50  ?  662 SER B C   1 
ATOM   10322 O O   . SER B 1 673 ? 142.106 155.147 129.174 1.00 45.50  ?  662 SER B O   1 
ATOM   10323 C CB  . SER B 1 673 ? 141.404 153.570 131.982 1.00 45.50  ?  662 SER B CB  1 
ATOM   10324 O OG  . SER B 1 673 ? 140.794 153.644 133.256 1.00 45.50  ?  662 SER B OG  1 
ATOM   10325 N N   . SER B 1 674 ? 141.020 153.259 128.901 1.00 43.51  ?  663 SER B N   1 
ATOM   10326 C CA  . SER B 1 674 ? 141.636 152.994 127.611 1.00 43.51  ?  663 SER B CA  1 
ATOM   10327 C C   . SER B 1 674 ? 141.108 153.878 126.496 1.00 43.51  ?  663 SER B C   1 
ATOM   10328 O O   . SER B 1 674 ? 141.857 154.239 125.598 1.00 43.51  ?  663 SER B O   1 
ATOM   10329 C CB  . SER B 1 674 ? 141.451 151.518 127.238 1.00 43.51  ?  663 SER B CB  1 
ATOM   10330 O OG  . SER B 1 674 ? 140.084 151.182 127.098 1.00 43.51  ?  663 SER B OG  1 
ATOM   10331 N N   . VAL B 1 675 ? 139.800 154.204 126.539 1.00 47.95  ?  664 VAL B N   1 
ATOM   10332 C CA  . VAL B 1 675 ? 139.266 155.090 125.526 1.00 47.95  ?  664 VAL B CA  1 
ATOM   10333 C C   . VAL B 1 675 ? 139.956 156.436 125.655 1.00 47.95  ?  664 VAL B C   1 
ATOM   10334 O O   . VAL B 1 675 ? 140.280 157.062 124.654 1.00 47.95  ?  664 VAL B O   1 
ATOM   10335 C CB  . VAL B 1 675 ? 137.724 155.230 125.594 1.00 47.95  ?  664 VAL B CB  1 
ATOM   10336 C CG1 . VAL B 1 675 ? 137.054 153.875 125.441 1.00 47.95  ?  664 VAL B CG1 1 
ATOM   10337 C CG2 . VAL B 1 675 ? 137.288 155.913 126.878 1.00 47.95  ?  664 VAL B CG2 1 
ATOM   10338 N N   . ARG B 1 676 ? 140.205 156.866 126.883 1.00 47.56  ?  665 ARG B N   1 
ATOM   10339 C CA  . ARG B 1 676 ? 140.893 158.130 127.104 1.00 47.56  ?  665 ARG B CA  1 
ATOM   10340 C C   . ARG B 1 676 ? 142.325 158.074 126.601 1.00 47.56  ?  665 ARG B C   1 
ATOM   10341 O O   . ARG B 1 676 ? 142.788 159.003 125.948 1.00 47.56  ?  665 ARG B O   1 
ATOM   10342 C CB  . ARG B 1 676 ? 140.848 158.514 128.583 1.00 47.56  ?  665 ARG B CB  1 
ATOM   10343 C CG  . ARG B 1 676 ? 139.456 158.877 129.066 1.00 47.56  ?  665 ARG B CG  1 
ATOM   10344 C CD  . ARG B 1 676 ? 139.412 159.090 130.568 1.00 47.56  ?  665 ARG B CD  1 
ATOM   10345 N NE  . ARG B 1 676 ? 138.062 159.404 131.025 1.00 47.56  ?  665 ARG B NE  1 
ATOM   10346 C CZ  . ARG B 1 676 ? 137.716 159.544 132.300 1.00 47.56  ?  665 ARG B CZ  1 
ATOM   10347 N NH1 . ARG B 1 676 ? 138.621 159.391 133.255 1.00 47.56  1  665 ARG B NH1 1 
ATOM   10348 N NH2 . ARG B 1 676 ? 136.462 159.830 132.620 1.00 47.56  ?  665 ARG B NH2 1 
ATOM   10349 N N   . GLY B 1 677 ? 143.021 156.981 126.880 1.00 46.93  ?  666 GLY B N   1 
ATOM   10350 C CA  . GLY B 1 677 ? 144.379 156.828 126.401 1.00 46.93  ?  666 GLY B CA  1 
ATOM   10351 C C   . GLY B 1 677 ? 144.429 156.754 124.899 1.00 46.93  ?  666 GLY B C   1 
ATOM   10352 O O   . GLY B 1 677 ? 145.310 157.334 124.282 1.00 46.93  ?  666 GLY B O   1 
ATOM   10353 N N   . LEU B 1 678 ? 143.446 156.023 124.328 1.00 48.42  ?  667 LEU B N   1 
ATOM   10354 C CA  . LEU B 1 678 ? 143.375 155.899 122.886 1.00 48.42  ?  667 LEU B CA  1 
ATOM   10355 C C   . LEU B 1 678 ? 143.142 157.246 122.214 1.00 48.42  ?  667 LEU B C   1 
ATOM   10356 O O   . LEU B 1 678 ? 143.779 157.559 121.220 1.00 48.42  ?  667 LEU B O   1 
ATOM   10357 C CB  . LEU B 1 678 ? 142.286 154.909 122.487 1.00 48.42  ?  667 LEU B CB  1 
ATOM   10358 C CG  . LEU B 1 678 ? 142.135 154.657 120.986 1.00 48.42  ?  667 LEU B CG  1 
ATOM   10359 C CD1 . LEU B 1 678 ? 143.439 154.148 120.392 1.00 48.42  ?  667 LEU B CD1 1 
ATOM   10360 C CD2 . LEU B 1 678 ? 141.001 153.682 120.718 1.00 48.42  ?  667 LEU B CD2 1 
ATOM   10361 N N   . LYS B 1 679 ? 142.219 158.025 122.738 1.00 48.82  ?  668 LYS B N   1 
ATOM   10362 C CA  . LYS B 1 679 ? 141.888 159.323 122.198 1.00 48.82  ?  668 LYS B CA  1 
ATOM   10363 C C   . LYS B 1 679 ? 143.089 160.261 122.192 1.00 48.82  ?  668 LYS B C   1 
ATOM   10364 O O   . LYS B 1 679 ? 143.329 160.996 121.249 1.00 48.82  ?  668 LYS B O   1 
ATOM   10365 C CB  . LYS B 1 679 ? 140.767 159.901 123.044 1.00 48.82  ?  668 LYS B CB  1 
ATOM   10366 C CG  . LYS B 1 679 ? 140.533 161.373 122.894 1.00 48.82  ?  668 LYS B CG  1 
ATOM   10367 C CD  . LYS B 1 679 ? 139.591 161.639 121.756 1.00 48.82  ?  668 LYS B CD  1 
ATOM   10368 C CE  . LYS B 1 679 ? 138.878 162.950 121.969 1.00 48.82  ?  668 LYS B CE  1 
ATOM   10369 N NZ  . LYS B 1 679 ? 137.821 163.132 120.955 1.00 48.82  1  668 LYS B NZ  1 
ATOM   10370 N N   . SER B 1 680 ? 143.827 160.230 123.280 1.00 49.16  ?  669 SER B N   1 
ATOM   10371 C CA  . SER B 1 680 ? 145.000 161.031 123.459 1.00 49.16  ?  669 SER B CA  1 
ATOM   10372 C C   . SER B 1 680 ? 146.086 160.677 122.456 1.00 49.16  ?  669 SER B C   1 
ATOM   10373 O O   . SER B 1 680 ? 146.735 161.546 121.938 1.00 49.16  ?  669 SER B O   1 
ATOM   10374 C CB  . SER B 1 680 ? 145.462 160.863 124.894 1.00 49.16  ?  669 SER B CB  1 
ATOM   10375 O OG  . SER B 1 680 ? 146.760 161.336 125.084 1.00 49.16  ?  669 SER B OG  1 
ATOM   10376 N N   . ILE B 1 681 ? 146.261 159.387 122.200 1.00 49.73  ?  670 ILE B N   1 
ATOM   10377 C CA  . ILE B 1 681 ? 147.214 158.849 121.245 1.00 49.73  ?  670 ILE B CA  1 
ATOM   10378 C C   . ILE B 1 681 ? 146.848 159.287 119.837 1.00 49.73  ?  670 ILE B C   1 
ATOM   10379 O O   . ILE B 1 681 ? 147.682 159.768 119.117 1.00 49.73  ?  670 ILE B O   1 
ATOM   10380 C CB  . ILE B 1 681 ? 147.179 157.302 121.260 1.00 49.73  ?  670 ILE B CB  1 
ATOM   10381 C CG1 . ILE B 1 681 ? 147.975 156.742 122.412 1.00 49.73  ?  670 ILE B CG1 1 
ATOM   10382 C CG2 . ILE B 1 681 ? 147.731 156.711 119.978 1.00 49.73  ?  670 ILE B CG2 1 
ATOM   10383 C CD1 . ILE B 1 681 ? 147.618 155.313 122.723 1.00 49.73  ?  670 ILE B CD1 1 
ATOM   10384 N N   . LEU B 1 682 ? 145.592 159.102 119.462 1.00 51.38  ?  671 LEU B N   1 
ATOM   10385 C CA  . LEU B 1 682 ? 145.121 159.464 118.139 1.00 51.38  ?  671 LEU B CA  1 
ATOM   10386 C C   . LEU B 1 682 ? 145.204 160.958 117.890 1.00 51.38  ?  671 LEU B C   1 
ATOM   10387 O O   . LEU B 1 682 ? 145.614 161.380 116.817 1.00 51.38  ?  671 LEU B O   1 
ATOM   10388 C CB  . LEU B 1 682 ? 143.687 158.973 117.946 1.00 51.38  ?  671 LEU B CB  1 
ATOM   10389 C CG  . LEU B 1 682 ? 143.480 157.469 118.110 1.00 51.38  ?  671 LEU B CG  1 
ATOM   10390 C CD1 . LEU B 1 682 ? 142.126 157.061 117.554 1.00 51.38  ?  671 LEU B CD1 1 
ATOM   10391 C CD2 . LEU B 1 682 ? 144.591 156.699 117.415 1.00 51.38  ?  671 LEU B CD2 1 
ATOM   10392 N N   . GLN B 1 683 ? 144.926 161.762 118.903 1.00 53.32  ?  672 GLN B N   1 
ATOM   10393 C CA  . GLN B 1 683 ? 145.036 163.198 118.765 1.00 53.32  ?  672 GLN B CA  1 
ATOM   10394 C C   . GLN B 1 683 ? 146.453 163.628 118.494 1.00 53.32  ?  672 GLN B C   1 
ATOM   10395 O O   . GLN B 1 683 ? 146.673 164.435 117.635 1.00 53.32  ?  672 GLN B O   1 
ATOM   10396 C CB  . GLN B 1 683 ? 144.513 163.917 119.984 1.00 53.32  ?  672 GLN B CB  1 
ATOM   10397 C CG  . GLN B 1 683 ? 143.024 164.037 119.971 1.00 53.32  ?  672 GLN B CG  1 
ATOM   10398 C CD  . GLN B 1 683 ? 142.479 164.539 121.269 1.00 53.32  ?  672 GLN B CD  1 
ATOM   10399 O OE1 . GLN B 1 683 ? 141.463 165.202 121.293 1.00 53.32  ?  672 GLN B OE1 1 
ATOM   10400 N NE2 . GLN B 1 683 ? 143.145 164.215 122.358 1.00 53.32  ?  672 GLN B NE2 1 
ATOM   10401 N N   . GLU B 1 684 ? 147.423 163.094 119.215 1.00 50.67  ?  673 GLU B N   1 
ATOM   10402 C CA  . GLU B 1 684 ? 148.779 163.505 118.925 1.00 50.67  ?  673 GLU B CA  1 
ATOM   10403 C C   . GLU B 1 684 ? 149.281 163.014 117.570 1.00 50.67  ?  673 GLU B C   1 
ATOM   10404 O O   . GLU B 1 684 ? 150.168 163.609 117.015 1.00 50.67  ?  673 GLU B O   1 
ATOM   10405 C CB  . GLU B 1 684 ? 149.770 163.327 120.098 1.00 50.67  ?  673 GLU B CB  1 
ATOM   10406 C CG  . GLU B 1 684 ? 149.785 161.991 120.784 1.00 50.67  ?  673 GLU B CG  1 
ATOM   10407 C CD  . GLU B 1 684 ? 149.787 162.099 122.302 1.00 50.67  ?  673 GLU B CD  1 
ATOM   10408 O OE1 . GLU B 1 684 ? 149.281 163.095 122.859 1.00 50.67  ?  673 GLU B OE1 1 
ATOM   10409 O OE2 . GLU B 1 684 ? 150.266 161.159 122.951 1.00 50.67  -1 673 GLU B OE2 1 
ATOM   10410 N N   . PHE B 1 685 ? 148.718 161.942 117.029 1.00 54.54  ?  674 PHE B N   1 
ATOM   10411 C CA  . PHE B 1 685 ? 149.141 161.514 115.694 1.00 54.54  ?  674 PHE B CA  1 
ATOM   10412 C C   . PHE B 1 685 ? 148.470 162.368 114.631 1.00 54.54  ?  674 PHE B C   1 
ATOM   10413 O O   . PHE B 1 685 ? 149.082 162.701 113.625 1.00 54.54  ?  674 PHE B O   1 
ATOM   10414 C CB  . PHE B 1 685 ? 148.832 160.039 115.450 1.00 54.54  ?  674 PHE B CB  1 
ATOM   10415 C CG  . PHE B 1 685 ? 149.889 159.100 115.945 1.00 54.54  ?  674 PHE B CG  1 
ATOM   10416 C CD1 . PHE B 1 685 ? 149.650 158.278 117.032 1.00 54.54  ?  674 PHE B CD1 1 
ATOM   10417 C CD2 . PHE B 1 685 ? 151.118 159.029 115.315 1.00 54.54  ?  674 PHE B CD2 1 
ATOM   10418 C CE1 . PHE B 1 685 ? 150.620 157.409 117.486 1.00 54.54  ?  674 PHE B CE1 1 
ATOM   10419 C CE2 . PHE B 1 685 ? 152.093 158.161 115.765 1.00 54.54  ?  674 PHE B CE2 1 
ATOM   10420 C CZ  . PHE B 1 685 ? 151.844 157.350 116.852 1.00 54.54  ?  674 PHE B CZ  1 
ATOM   10421 N N   . ILE B 1 686 ? 147.228 162.748 114.861 1.00 57.16  ?  675 ILE B N   1 
ATOM   10422 C CA  . ILE B 1 686 ? 146.532 163.596 113.920 1.00 57.16  ?  675 ILE B CA  1 
ATOM   10423 C C   . ILE B 1 686 ? 147.126 164.997 113.899 1.00 57.16  ?  675 ILE B C   1 
ATOM   10424 O O   . ILE B 1 686 ? 147.193 165.624 112.847 1.00 57.16  ?  675 ILE B O   1 
ATOM   10425 C CB  . ILE B 1 686 ? 145.033 163.636 114.250 1.00 57.16  ?  675 ILE B CB  1 
ATOM   10426 C CG1 . ILE B 1 686 ? 144.433 162.249 114.021 1.00 57.16  ?  675 ILE B CG1 1 
ATOM   10427 C CG2 . ILE B 1 686 ? 144.316 164.675 113.407 1.00 57.16  ?  675 ILE B CG2 1 
ATOM   10428 C CD1 . ILE B 1 686 ? 143.065 162.053 114.625 1.00 57.16  ?  675 ILE B CD1 1 
ATOM   10429 N N   . ARG B 1 687 ? 147.579 165.483 115.048 1.00 58.20  ?  676 ARG B N   1 
ATOM   10430 C CA  . ARG B 1 687 ? 148.140 166.830 115.131 1.00 58.20  ?  676 ARG B CA  1 
ATOM   10431 C C   . ARG B 1 687 ? 149.498 166.952 114.448 1.00 58.20  ?  676 ARG B C   1 
ATOM   10432 O O   . ARG B 1 687 ? 149.907 168.050 114.097 1.00 58.20  ?  676 ARG B O   1 
ATOM   10433 C CB  . ARG B 1 687 ? 148.183 167.294 116.587 1.00 58.20  ?  676 ARG B CB  1 
ATOM   10434 C CG  . ARG B 1 687 ? 146.804 167.664 117.097 1.00 58.20  ?  676 ARG B CG  1 
ATOM   10435 C CD  . ARG B 1 687 ? 146.727 167.704 118.608 1.00 58.20  ?  676 ARG B CD  1 
ATOM   10436 N NE  . ARG B 1 687 ? 145.346 167.893 119.034 1.00 58.20  ?  676 ARG B NE  1 
ATOM   10437 C CZ  . ARG B 1 687 ? 144.950 167.925 120.299 1.00 58.20  ?  676 ARG B CZ  1 
ATOM   10438 N NH1 . ARG B 1 687 ? 145.832 167.779 121.275 1.00 58.20  1  676 ARG B NH1 1 
ATOM   10439 N NH2 . ARG B 1 687 ? 143.670 168.099 120.586 1.00 58.20  ?  676 ARG B NH2 1 
ATOM   10440 N N   . ILE B 1 688 ? 150.176 165.833 114.246 1.00 63.26  ?  677 ILE B N   1 
ATOM   10441 C CA  . ILE B 1 688 ? 151.440 165.843 113.528 1.00 63.26  ?  677 ILE B CA  1 
ATOM   10442 C C   . ILE B 1 688 ? 151.198 165.402 112.093 1.00 63.26  ?  677 ILE B C   1 
ATOM   10443 O O   . ILE B 1 688 ? 152.139 165.064 111.388 1.00 63.26  ?  677 ILE B O   1 
ATOM   10444 C CB  . ILE B 1 688 ? 152.492 164.956 114.215 1.00 63.26  ?  677 ILE B CB  1 
ATOM   10445 C CG1 . ILE B 1 688 ? 151.995 163.516 114.324 1.00 63.26  ?  677 ILE B CG1 1 
ATOM   10446 C CG2 . ILE B 1 688 ? 152.833 165.514 115.588 1.00 63.26  ?  677 ILE B CG2 1 
ATOM   10447 C CD1 . ILE B 1 688 ? 153.057 162.547 114.789 1.00 63.26  ?  677 ILE B CD1 1 
ATOM   10448 N N   . LYS B 1 689 ? 149.937 165.399 111.668 1.00 60.40  ?  678 LYS B N   1 
ATOM   10449 C CA  . LYS B 1 689 ? 149.567 165.042 110.285 1.00 60.40  ?  678 LYS B CA  1 
ATOM   10450 C C   . LYS B 1 689 ? 149.733 163.570 109.926 1.00 60.40  ?  678 LYS B C   1 
ATOM   10451 O O   . LYS B 1 689 ? 150.039 163.242 108.787 1.00 60.40  ?  678 LYS B O   1 
ATOM   10452 C CB  . LYS B 1 689 ? 150.318 165.923 109.278 1.00 30.00  ?  678 LYS B CB  1 
ATOM   10453 C CG  . LYS B 1 689 ? 150.107 167.405 109.515 1.00 30.00  ?  678 LYS B CG  1 
ATOM   10454 C CD  . LYS B 1 689 ? 148.625 167.722 109.582 1.00 30.00  ?  678 LYS B CD  1 
ATOM   10455 C CE  . LYS B 1 689 ? 148.379 169.029 110.311 1.00 30.00  ?  678 LYS B CE  1 
ATOM   10456 N NZ  . LYS B 1 689 ? 148.871 168.955 111.713 1.00 30.00  1  678 LYS B NZ  1 
ATOM   10457 N N   . VAL B 1 690 ? 149.535 162.685 110.889 1.00 53.57  ?  679 VAL B N   1 
ATOM   10458 C CA  . VAL B 1 690 ? 149.589 161.264 110.593 1.00 53.57  ?  679 VAL B CA  1 
ATOM   10459 C C   . VAL B 1 690 ? 148.170 160.762 110.616 1.00 53.57  ?  679 VAL B C   1 
ATOM   10460 O O   . VAL B 1 690 ? 147.505 160.828 111.641 1.00 53.57  ?  679 VAL B O   1 
ATOM   10461 C CB  . VAL B 1 690 ? 150.450 160.470 111.591 1.00 53.57  ?  679 VAL B CB  1 
ATOM   10462 C CG1 . VAL B 1 690 ? 150.314 158.976 111.342 1.00 53.57  ?  679 VAL B CG1 1 
ATOM   10463 C CG2 . VAL B 1 690 ? 151.904 160.903 111.503 1.00 53.57  ?  679 VAL B CG2 1 
ATOM   10464 N N   . ASP B 1 691 ? 147.692 160.283 109.479 1.00 51.13  ?  680 ASP B N   1 
ATOM   10465 C CA  . ASP B 1 691 ? 146.338 159.761 109.393 1.00 51.13  ?  680 ASP B CA  1 
ATOM   10466 C C   . ASP B 1 691 ? 146.223 158.449 110.125 1.00 51.13  ?  680 ASP B C   1 
ATOM   10467 O O   . ASP B 1 691 ? 147.009 157.538 109.902 1.00 51.13  ?  680 ASP B O   1 
ATOM   10468 C CB  . ASP B 1 691 ? 145.922 159.590 107.934 1.00 51.13  ?  680 ASP B CB  1 
ATOM   10469 C CG  . ASP B 1 691 ? 145.744 160.908 107.220 1.00 51.13  ?  680 ASP B CG  1 
ATOM   10470 O OD1 . ASP B 1 691 ? 145.706 161.956 107.898 1.00 51.13  ?  680 ASP B OD1 1 
ATOM   10471 O OD2 . ASP B 1 691 ? 145.637 160.899 105.979 1.00 51.13  -1 680 ASP B OD2 1 
ATOM   10472 N N   . VAL B 1 692 ? 145.246 158.353 111.012 1.00 47.03  ?  681 VAL B N   1 
ATOM   10473 C CA  . VAL B 1 692 ? 145.037 157.136 111.765 1.00 47.03  ?  681 VAL B CA  1 
ATOM   10474 C C   . VAL B 1 692 ? 143.829 156.356 111.286 1.00 47.03  ?  681 VAL B C   1 
ATOM   10475 O O   . VAL B 1 692 ? 142.764 156.917 111.097 1.00 47.03  ?  681 VAL B O   1 
ATOM   10476 C CB  . VAL B 1 692 ? 144.886 157.459 113.255 1.00 47.03  ?  681 VAL B CB  1 
ATOM   10477 C CG1 . VAL B 1 692 ? 144.604 156.202 114.052 1.00 47.03  ?  681 VAL B CG1 1 
ATOM   10478 C CG2 . VAL B 1 692 ? 146.142 158.137 113.761 1.00 47.03  ?  681 VAL B CG2 1 
ATOM   10479 N N   . TYR B 1 693 ? 144.021 155.060 111.070 1.00 44.12  ?  682 TYR B N   1 
ATOM   10480 C CA  . TYR B 1 693 ? 142.966 154.157 110.641 1.00 44.12  ?  682 TYR B CA  1 
ATOM   10481 C C   . TYR B 1 693 ? 142.811 153.041 111.659 1.00 44.12  ?  682 TYR B C   1 
ATOM   10482 O O   . TYR B 1 693 ? 143.801 152.475 112.122 1.00 44.12  ?  682 TYR B O   1 
ATOM   10483 C CB  . TYR B 1 693 ? 143.266 153.556 109.270 1.00 44.12  ?  682 TYR B CB  1 
ATOM   10484 C CG  . TYR B 1 693 ? 143.550 154.578 108.200 1.00 44.12  ?  682 TYR B CG  1 
ATOM   10485 C CD1 . TYR B 1 693 ? 142.531 155.094 107.424 1.00 44.12  ?  682 TYR B CD1 1 
ATOM   10486 C CD2 . TYR B 1 693 ? 144.839 155.023 107.965 1.00 44.12  ?  682 TYR B CD2 1 
ATOM   10487 C CE1 . TYR B 1 693 ? 142.785 156.024 106.449 1.00 44.12  ?  682 TYR B CE1 1 
ATOM   10488 C CE2 . TYR B 1 693 ? 145.099 155.956 106.992 1.00 44.12  ?  682 TYR B CE2 1 
ATOM   10489 C CZ  . TYR B 1 693 ? 144.068 156.451 106.235 1.00 44.12  ?  682 TYR B CZ  1 
ATOM   10490 O OH  . TYR B 1 693 ? 144.323 157.382 105.261 1.00 44.12  ?  682 TYR B OH  1 
ATOM   10491 N N   . ILE B 1 694 ? 141.568 152.729 112.009 1.00 42.80  ?  683 ILE B N   1 
ATOM   10492 C CA  . ILE B 1 694 ? 141.251 151.616 112.894 1.00 42.80  ?  683 ILE B CA  1 
ATOM   10493 C C   . ILE B 1 694 ? 140.433 150.619 112.096 1.00 42.80  ?  683 ILE B C   1 
ATOM   10494 O O   . ILE B 1 694 ? 139.366 150.961 111.575 1.00 42.80  ?  683 ILE B O   1 
ATOM   10495 C CB  . ILE B 1 694 ? 140.491 152.071 114.148 1.00 42.80  ?  683 ILE B CB  1 
ATOM   10496 C CG1 . ILE B 1 694 ? 141.331 153.062 114.951 1.00 42.80  ?  683 ILE B CG1 1 
ATOM   10497 C CG2 . ILE B 1 694 ? 140.128 150.879 115.000 1.00 42.80  ?  683 ILE B CG2 1 
ATOM   10498 C CD1 . ILE B 1 694 ? 140.833 153.289 116.347 1.00 42.80  ?  683 ILE B CD1 1 
ATOM   10499 N N   . VAL B 1 695 ? 140.930 149.390 111.994 1.00 43.73  ?  684 VAL B N   1 
ATOM   10500 C CA  . VAL B 1 695 ? 140.368 148.391 111.101 1.00 43.73  ?  684 VAL B CA  1 
ATOM   10501 C C   . VAL B 1 695 ? 140.067 147.123 111.888 1.00 43.73  ?  684 VAL B C   1 
ATOM   10502 O O   . VAL B 1 695 ? 140.585 146.902 112.983 1.00 43.73  ?  684 VAL B O   1 
ATOM   10503 C CB  . VAL B 1 695 ? 141.314 148.086 109.926 1.00 43.73  ?  684 VAL B CB  1 
ATOM   10504 C CG1 . VAL B 1 695 ? 141.646 149.354 109.172 1.00 43.73  ?  684 VAL B CG1 1 
ATOM   10505 C CG2 . VAL B 1 695 ? 142.575 147.447 110.435 1.00 43.73  ?  684 VAL B CG2 1 
ATOM   10506 N N   . GLY B 1 696 ? 139.209 146.288 111.311 1.00 46.63  ?  685 GLY B N   1 
ATOM   10507 C CA  . GLY B 1 696 ? 138.917 144.987 111.877 1.00 46.63  ?  685 GLY B CA  1 
ATOM   10508 C C   . GLY B 1 696 ? 137.847 144.958 112.941 1.00 46.63  ?  685 GLY B C   1 
ATOM   10509 O O   . GLY B 1 696 ? 137.592 143.890 113.505 1.00 46.63  ?  685 GLY B O   1 
ATOM   10510 N N   . THR B 1 697 ? 137.206 146.084 113.227 1.00 51.89  ?  686 THR B N   1 
ATOM   10511 C CA  . THR B 1 697 ? 136.210 146.167 114.282 1.00 51.89  ?  686 THR B CA  1 
ATOM   10512 C C   . THR B 1 697 ? 134.816 145.893 113.735 1.00 51.89  ?  686 THR B C   1 
ATOM   10513 O O   . THR B 1 697 ? 134.500 146.222 112.590 1.00 51.89  ?  686 THR B O   1 
ATOM   10514 C CB  . THR B 1 697 ? 136.238 147.546 114.935 1.00 51.89  ?  686 THR B CB  1 
ATOM   10515 O OG1 . THR B 1 697 ? 136.247 148.553 113.918 1.00 51.89  ?  686 THR B OG1 1 
ATOM   10516 C CG2 . THR B 1 697 ? 137.469 147.696 115.777 1.00 51.89  ?  686 THR B CG2 1 
ATOM   10517 N N   . ASP B 1 698 ? 133.980 145.285 114.573 1.00 57.20  ?  687 ASP B N   1 
ATOM   10518 C CA  . ASP B 1 698 ? 132.589 145.051 114.221 1.00 57.20  ?  687 ASP B CA  1 
ATOM   10519 C C   . ASP B 1 698 ? 131.767 146.305 114.501 1.00 57.20  ?  687 ASP B C   1 
ATOM   10520 O O   . ASP B 1 698 ? 132.273 147.316 114.991 1.00 57.20  ?  687 ASP B O   1 
ATOM   10521 C CB  . ASP B 1 698 ? 132.044 143.842 114.976 1.00 57.20  ?  687 ASP B CB  1 
ATOM   10522 C CG  . ASP B 1 698 ? 132.505 143.798 116.413 1.00 57.20  ?  687 ASP B CG  1 
ATOM   10523 O OD1 . ASP B 1 698 ? 131.761 143.264 117.261 1.00 57.20  ?  687 ASP B OD1 1 
ATOM   10524 O OD2 . ASP B 1 698 ? 133.612 144.300 116.694 1.00 57.20  -1 687 ASP B OD2 1 
ATOM   10525 N N   . ASP B 1 699 ? 130.474 146.244 114.182 1.00 60.46  ?  688 ASP B N   1 
ATOM   10526 C CA  . ASP B 1 699 ? 129.620 147.418 114.330 1.00 60.46  ?  688 ASP B CA  1 
ATOM   10527 C C   . ASP B 1 699 ? 129.292 147.709 115.787 1.00 60.46  ?  688 ASP B C   1 
ATOM   10528 O O   . ASP B 1 699 ? 129.093 148.874 116.153 1.00 60.46  ?  688 ASP B O   1 
ATOM   10529 C CB  . ASP B 1 699 ? 128.335 147.233 113.526 1.00 60.46  ?  688 ASP B CB  1 
ATOM   10530 C CG  . ASP B 1 699 ? 128.601 146.964 112.058 1.00 60.46  ?  688 ASP B CG  1 
ATOM   10531 O OD1 . ASP B 1 699 ? 127.803 146.234 111.433 1.00 60.46  ?  688 ASP B OD1 1 
ATOM   10532 O OD2 . ASP B 1 699 ? 129.609 147.476 111.528 1.00 60.46  -1 688 ASP B OD2 1 
ATOM   10533 N N   . ASP B 1 700 ? 129.236 146.677 116.629 1.00 59.39  ?  689 ASP B N   1 
ATOM   10534 C CA  . ASP B 1 700 ? 128.992 146.899 118.049 1.00 59.39  ?  689 ASP B CA  1 
ATOM   10535 C C   . ASP B 1 700 ? 130.134 147.671 118.694 1.00 59.39  ?  689 ASP B C   1 
ATOM   10536 O O   . ASP B 1 700 ? 129.903 148.472 119.604 1.00 59.39  ?  689 ASP B O   1 
ATOM   10537 C CB  . ASP B 1 700 ? 128.784 145.564 118.759 1.00 59.39  ?  689 ASP B CB  1 
ATOM   10538 C CG  . ASP B 1 700 ? 127.637 144.766 118.175 1.00 59.39  ?  689 ASP B CG  1 
ATOM   10539 O OD1 . ASP B 1 700 ? 127.813 144.167 117.094 1.00 59.39  ?  689 ASP B OD1 1 
ATOM   10540 O OD2 . ASP B 1 700 ? 126.554 144.737 118.797 1.00 59.39  -1 689 ASP B OD2 1 
ATOM   10541 N N   . PHE B 1 701 ? 131.363 147.456 118.224 1.00 53.52  ?  690 PHE B N   1 
ATOM   10542 C CA  . PHE B 1 701 ? 132.510 148.185 118.752 1.00 53.52  ?  690 PHE B CA  1 
ATOM   10543 C C   . PHE B 1 701 ? 132.372 149.681 118.505 1.00 53.52  ?  690 PHE B C   1 
ATOM   10544 O O   . PHE B 1 701 ? 132.569 150.496 119.411 1.00 53.52  ?  690 PHE B O   1 
ATOM   10545 C CB  . PHE B 1 701 ? 133.790 147.643 118.116 1.00 53.52  ?  690 PHE B CB  1 
ATOM   10546 C CG  . PHE B 1 701 ? 135.050 148.085 118.797 1.00 53.52  ?  690 PHE B CG  1 
ATOM   10547 C CD1 . PHE B 1 701 ? 135.709 149.230 118.386 1.00 53.52  ?  690 PHE B CD1 1 
ATOM   10548 C CD2 . PHE B 1 701 ? 135.590 147.349 119.835 1.00 53.52  ?  690 PHE B CD2 1 
ATOM   10549 C CE1 . PHE B 1 701 ? 136.864 149.631 118.998 1.00 53.52  ?  690 PHE B CE1 1 
ATOM   10550 C CE2 . PHE B 1 701 ? 136.749 147.751 120.451 1.00 53.52  ?  690 PHE B CE2 1 
ATOM   10551 C CZ  . PHE B 1 701 ? 137.385 148.891 120.033 1.00 53.52  ?  690 PHE B CZ  1 
ATOM   10552 N N   . ILE B 1 702 ? 132.014 150.063 117.278 1.00 55.53  ?  691 ILE B N   1 
ATOM   10553 C CA  . ILE B 1 702 ? 131.865 151.476 116.952 1.00 55.53  ?  691 ILE B CA  1 
ATOM   10554 C C   . ILE B 1 702 ? 130.639 152.065 117.633 1.00 55.53  ?  691 ILE B C   1 
ATOM   10555 O O   . ILE B 1 702 ? 130.646 153.232 118.045 1.00 55.53  ?  691 ILE B O   1 
ATOM   10556 C CB  . ILE B 1 702 ? 131.812 151.657 115.426 1.00 55.53  ?  691 ILE B CB  1 
ATOM   10557 C CG1 . ILE B 1 702 ? 132.833 150.737 114.758 1.00 55.53  ?  691 ILE B CG1 1 
ATOM   10558 C CG2 . ILE B 1 702 ? 132.054 153.107 115.051 1.00 55.53  ?  691 ILE B CG2 1 
ATOM   10559 C CD1 . ILE B 1 702 ? 132.522 150.415 113.327 1.00 55.53  ?  691 ILE B CD1 1 
ATOM   10560 N N   . GLU B 1 703 ? 129.649 151.238 117.926 1.00 57.75  ?  692 GLU B N   1 
ATOM   10561 C CA  . GLU B 1 703 ? 128.499 151.735 118.669 1.00 57.75  ?  692 GLU B CA  1 
ATOM   10562 C C   . GLU B 1 703 ? 128.879 152.108 120.105 1.00 57.75  ?  692 GLU B C   1 
ATOM   10563 O O   . GLU B 1 703 ? 128.542 153.194 120.578 1.00 57.75  ?  692 GLU B O   1 
ATOM   10564 C CB  . GLU B 1 703 ? 127.371 150.709 118.661 1.00 57.75  ?  692 GLU B CB  1 
ATOM   10565 C CG  . GLU B 1 703 ? 126.210 151.078 119.566 1.00 57.75  ?  692 GLU B CG  1 
ATOM   10566 C CD  . GLU B 1 703 ? 125.727 152.499 119.345 1.00 57.75  ?  692 GLU B CD  1 
ATOM   10567 O OE1 . GLU B 1 703 ? 125.680 152.944 118.178 1.00 57.75  ?  692 GLU B OE1 1 
ATOM   10568 O OE2 . GLU B 1 703 ? 125.391 153.174 120.342 1.00 57.75  -1 692 GLU B OE2 1 
ATOM   10569 N N   . LYS B 1 704 ? 129.589 151.236 120.803 1.00 55.73  ?  693 LYS B N   1 
ATOM   10570 C CA  . LYS B 1 704 ? 130.005 151.533 122.155 1.00 55.73  ?  693 LYS B CA  1 
ATOM   10571 C C   . LYS B 1 704 ? 130.888 152.744 122.202 1.00 55.73  ?  693 LYS B C   1 
ATOM   10572 O O   . LYS B 1 704 ? 130.742 153.578 123.067 1.00 55.73  ?  693 LYS B O   1 
ATOM   10573 C CB  . LYS B 1 704 ? 130.765 150.370 122.761 1.00 55.73  ?  693 LYS B CB  1 
ATOM   10574 C CG  . LYS B 1 704 ? 129.935 149.144 122.987 1.00 55.73  ?  693 LYS B CG  1 
ATOM   10575 C CD  . LYS B 1 704 ? 130.526 148.297 124.079 1.00 55.73  ?  693 LYS B CD  1 
ATOM   10576 C CE  . LYS B 1 704 ? 129.709 147.043 124.239 1.00 55.73  ?  693 LYS B CE  1 
ATOM   10577 N NZ  . LYS B 1 704 ? 129.481 146.473 122.892 1.00 55.73  1  693 LYS B NZ  1 
ATOM   10578 N N   . LEU B 1 705 ? 131.825 152.832 121.277 1.00 54.31  ?  694 LEU B N   1 
ATOM   10579 C CA  . LEU B 1 705 ? 132.755 153.956 121.261 1.00 54.31  ?  694 LEU B CA  1 
ATOM   10580 C C   . LEU B 1 705 ? 132.016 155.280 121.143 1.00 54.31  ?  694 LEU B C   1 
ATOM   10581 O O   . LEU B 1 705 ? 132.481 156.294 121.649 1.00 54.31  ?  694 LEU B O   1 
ATOM   10582 C CB  . LEU B 1 705 ? 133.759 153.791 120.124 1.00 54.31  ?  694 LEU B CB  1 
ATOM   10583 C CG  . LEU B 1 705 ? 135.099 154.509 120.237 1.00 54.31  ?  694 LEU B CG  1 
ATOM   10584 C CD1 . LEU B 1 705 ? 135.741 154.237 121.588 1.00 54.31  ?  694 LEU B CD1 1 
ATOM   10585 C CD2 . LEU B 1 705 ? 136.011 154.058 119.107 1.00 54.31  ?  694 LEU B CD2 1 
ATOM   10586 N N   . ASN B 1 706 ? 130.874 155.285 120.468 1.00 57.32  ?  695 ASN B N   1 
ATOM   10587 C CA  . ASN B 1 706 ? 130.063 156.496 120.372 1.00 57.32  ?  695 ASN B CA  1 
ATOM   10588 C C   . ASN B 1 706 ? 129.535 156.929 121.736 1.00 57.32  ?  695 ASN B C   1 
ATOM   10589 O O   . ASN B 1 706 ? 129.383 158.117 121.994 1.00 57.32  ?  695 ASN B O   1 
ATOM   10590 C CB  . ASN B 1 706 ? 128.891 156.284 119.416 1.00 57.32  ?  695 ASN B CB  1 
ATOM   10591 C CG  . ASN B 1 706 ? 129.335 155.942 118.013 1.00 57.32  ?  695 ASN B CG  1 
ATOM   10592 O OD1 . ASN B 1 706 ? 130.329 156.465 117.520 1.00 57.32  ?  695 ASN B OD1 1 
ATOM   10593 N ND2 . ASN B 1 706 ? 128.589 155.065 117.356 1.00 57.32  ?  695 ASN B ND2 1 
ATOM   10594 N N   . ARG B 1 707 ? 129.249 155.970 122.608 1.00 56.62  ?  696 ARG B N   1 
ATOM   10595 C CA  . ARG B 1 707 ? 128.781 156.291 123.954 1.00 56.62  ?  696 ARG B CA  1 
ATOM   10596 C C   . ARG B 1 707 ? 129.868 156.911 124.828 1.00 56.62  ?  696 ARG B C   1 
ATOM   10597 O O   . ARG B 1 707 ? 129.561 157.565 125.817 1.00 56.62  ?  696 ARG B O   1 
ATOM   10598 C CB  . ARG B 1 707 ? 128.234 155.032 124.626 1.00 56.62  ?  696 ARG B CB  1 
ATOM   10599 C CG  . ARG B 1 707 ? 127.333 154.205 123.727 1.00 56.62  ?  696 ARG B CG  1 
ATOM   10600 C CD  . ARG B 1 707 ? 127.180 152.789 124.254 1.00 56.62  ?  696 ARG B CD  1 
ATOM   10601 N NE  . ARG B 1 707 ? 126.587 151.904 123.257 1.00 56.62  ?  696 ARG B NE  1 
ATOM   10602 C CZ  . ARG B 1 707 ? 126.419 150.597 123.424 1.00 56.62  ?  696 ARG B CZ  1 
ATOM   10603 N NH1 . ARG B 1 707 ? 125.872 149.868 122.462 1.00 56.62  1  696 ARG B NH1 1 
ATOM   10604 N NH2 . ARG B 1 707 ? 126.802 150.018 124.553 1.00 56.62  ?  696 ARG B NH2 1 
ATOM   10605 N N   . TYR B 1 708 ? 131.131 156.702 124.474 1.00 53.13  ?  697 TYR B N   1 
ATOM   10606 C CA  . TYR B 1 708 ? 132.239 157.255 125.243 1.00 53.13  ?  697 TYR B CA  1 
ATOM   10607 C C   . TYR B 1 708 ? 132.577 158.662 124.820 1.00 53.13  ?  697 TYR B C   1 
ATOM   10608 O O   . TYR B 1 708 ? 133.507 159.253 125.352 1.00 53.13  ?  697 TYR B O   1 
ATOM   10609 C CB  . TYR B 1 708 ? 133.494 156.407 125.074 1.00 53.13  ?  697 TYR B CB  1 
ATOM   10610 C CG  . TYR B 1 708 ? 133.493 155.087 125.800 1.00 53.13  ?  697 TYR B CG  1 
ATOM   10611 C CD1 . TYR B 1 708 ? 133.130 153.919 125.150 1.00 53.13  ?  697 TYR B CD1 1 
ATOM   10612 C CD2 . TYR B 1 708 ? 133.887 155.004 127.129 1.00 53.13  ?  697 TYR B CD2 1 
ATOM   10613 C CE1 . TYR B 1 708 ? 133.142 152.706 125.807 1.00 53.13  ?  697 TYR B CE1 1 
ATOM   10614 C CE2 . TYR B 1 708 ? 133.903 153.793 127.793 1.00 53.13  ?  697 TYR B CE2 1 
ATOM   10615 C CZ  . TYR B 1 708 ? 133.529 152.648 127.127 1.00 53.13  ?  697 TYR B CZ  1 
ATOM   10616 O OH  . TYR B 1 708 ? 133.541 151.439 127.774 1.00 53.13  ?  697 TYR B OH  1 
ATOM   10617 N N   . GLU B 1 709 ? 131.844 159.203 123.856 1.00 57.49  ?  698 GLU B N   1 
ATOM   10618 C CA  . GLU B 1 709 ? 132.146 160.534 123.340 1.00 57.49  ?  698 GLU B CA  1 
ATOM   10619 C C   . GLU B 1 709 ? 133.558 160.560 122.787 1.00 57.49  ?  698 GLU B C   1 
ATOM   10620 O O   . GLU B 1 709 ? 134.292 161.523 122.989 1.00 57.49  ?  698 GLU B O   1 
ATOM   10621 C CB  . GLU B 1 709 ? 131.962 161.589 124.428 1.00 57.49  ?  698 GLU B CB  1 
ATOM   10622 C CG  . GLU B 1 709 ? 130.614 161.511 125.126 1.00 57.49  ?  698 GLU B CG  1 
ATOM   10623 C CD  . GLU B 1 709 ? 130.486 162.498 126.269 1.00 57.49  ?  698 GLU B CD  1 
ATOM   10624 O OE1 . GLU B 1 709 ? 129.447 162.470 126.963 1.00 57.49  ?  698 GLU B OE1 1 
ATOM   10625 O OE2 . GLU B 1 709 ? 131.424 163.297 126.478 1.00 57.49  -1 698 GLU B OE2 1 
ATOM   10626 N N   . PHE B 1 710 ? 133.936 159.506 122.079 1.00 52.46  ?  699 PHE B N   1 
ATOM   10627 C CA  . PHE B 1 710 ? 135.279 159.407 121.527 1.00 52.46  ?  699 PHE B CA  1 
ATOM   10628 C C   . PHE B 1 710 ? 135.446 160.275 120.301 1.00 52.46  ?  699 PHE B C   1 
ATOM   10629 O O   . PHE B 1 710 ? 136.499 160.863 120.096 1.00 52.46  ?  699 PHE B O   1 
ATOM   10630 C CB  . PHE B 1 710 ? 135.547 157.945 121.173 1.00 52.46  ?  699 PHE B CB  1 
ATOM   10631 C CG  . PHE B 1 710 ? 136.925 157.676 120.654 1.00 52.46  ?  699 PHE B CG  1 
ATOM   10632 C CD1 . PHE B 1 710 ? 137.136 157.455 119.305 1.00 52.46  ?  699 PHE B CD1 1 
ATOM   10633 C CD2 . PHE B 1 710 ? 138.003 157.617 121.517 1.00 52.46  ?  699 PHE B CD2 1 
ATOM   10634 C CE1 . PHE B 1 710 ? 138.401 157.192 118.825 1.00 52.46  ?  699 PHE B CE1 1 
ATOM   10635 C CE2 . PHE B 1 710 ? 139.271 157.356 121.043 1.00 52.46  ?  699 PHE B CE2 1 
ATOM   10636 C CZ  . PHE B 1 710 ? 139.472 157.145 119.696 1.00 52.46  ?  699 PHE B CZ  1 
ATOM   10637 N N   . PHE B 1 711 ? 134.409 160.361 119.482 1.00 54.62  ?  700 PHE B N   1 
ATOM   10638 C CA  . PHE B 1 711 ? 134.518 161.107 118.234 1.00 54.62  ?  700 PHE B CA  1 
ATOM   10639 C C   . PHE B 1 711 ? 134.231 162.585 118.383 1.00 54.62  ?  700 PHE B C   1 
ATOM   10640 O O   . PHE B 1 711 ? 133.394 162.982 119.184 1.00 54.62  ?  700 PHE B O   1 
ATOM   10641 C CB  . PHE B 1 711 ? 133.609 160.485 117.173 1.00 54.62  ?  700 PHE B CB  1 
ATOM   10642 C CG  . PHE B 1 711 ? 133.930 159.050 116.882 1.00 54.62  ?  700 PHE B CG  1 
ATOM   10643 C CD1 . PHE B 1 711 ? 135.079 158.715 116.188 1.00 54.62  ?  700 PHE B CD1 1 
ATOM   10644 C CD2 . PHE B 1 711 ? 133.096 158.037 117.319 1.00 54.62  ?  700 PHE B CD2 1 
ATOM   10645 C CE1 . PHE B 1 711 ? 135.384 157.395 115.924 1.00 54.62  ?  700 PHE B CE1 1 
ATOM   10646 C CE2 . PHE B 1 711 ? 133.395 156.715 117.058 1.00 54.62  ?  700 PHE B CE2 1 
ATOM   10647 C CZ  . PHE B 1 711 ? 134.540 156.394 116.360 1.00 54.62  ?  700 PHE B CZ  1 
ATOM   10648 N N   . ASP B 1 712 ? 134.930 163.401 117.607 1.00 59.01  ?  701 ASP B N   1 
ATOM   10649 C CA  . ASP B 1 712 ? 134.766 164.844 117.685 1.00 59.01  ?  701 ASP B CA  1 
ATOM   10650 C C   . ASP B 1 712 ? 135.313 165.433 116.402 1.00 59.01  ?  701 ASP B C   1 
ATOM   10651 O O   . ASP B 1 712 ? 135.434 164.735 115.401 1.00 59.01  ?  701 ASP B O   1 
ATOM   10652 C CB  . ASP B 1 712 ? 135.576 165.416 118.847 1.00 59.01  ?  701 ASP B CB  1 
ATOM   10653 C CG  . ASP B 1 712 ? 137.052 165.078 118.756 1.00 59.01  ?  701 ASP B CG  1 
ATOM   10654 O OD1 . ASP B 1 712 ? 137.426 164.233 117.920 1.00 59.01  ?  701 ASP B OD1 1 
ATOM   10655 O OD2 . ASP B 1 712 ? 137.839 165.653 119.532 1.00 59.01  -1 701 ASP B OD2 1 
ATOM   10656 N N   . GLY B 1 713 ? 135.650 166.716 116.426 1.00 61.36  ?  702 GLY B N   1 
ATOM   10657 C CA  . GLY B 1 713 ? 136.121 167.391 115.230 1.00 61.36  ?  702 GLY B CA  1 
ATOM   10658 C C   . GLY B 1 713 ? 137.421 166.851 114.674 1.00 61.36  ?  702 GLY B C   1 
ATOM   10659 O O   . GLY B 1 713 ? 137.599 166.804 113.462 1.00 61.36  ?  702 GLY B O   1 
ATOM   10660 N N   . GLU B 1 714 ? 138.334 166.448 115.548 1.00 60.31  ?  703 GLU B N   1 
ATOM   10661 C CA  . GLU B 1 714 ? 139.628 165.954 115.105 1.00 60.31  ?  703 GLU B CA  1 
ATOM   10662 C C   . GLU B 1 714 ? 139.584 164.456 114.855 1.00 60.31  ?  703 GLU B C   1 
ATOM   10663 O O   . GLU B 1 714 ? 140.008 163.991 113.804 1.00 60.31  ?  703 GLU B O   1 
ATOM   10664 C CB  . GLU B 1 714 ? 140.697 166.306 116.141 1.00 60.31  ?  703 GLU B CB  1 
ATOM   10665 C CG  . GLU B 1 714 ? 142.100 165.862 115.781 1.00 60.31  ?  703 GLU B CG  1 
ATOM   10666 C CD  . GLU B 1 714 ? 143.126 166.319 116.797 1.00 60.31  ?  703 GLU B CD  1 
ATOM   10667 O OE1 . GLU B 1 714 ? 142.733 166.952 117.799 1.00 60.31  ?  703 GLU B OE1 1 
ATOM   10668 O OE2 . GLU B 1 714 ? 144.325 166.045 116.595 1.00 60.31  -1 703 GLU B OE2 1 
ATOM   10669 N N   . VAL B 1 715 ? 139.073 163.700 115.815 1.00 56.37  ?  704 VAL B N   1 
ATOM   10670 C CA  . VAL B 1 715 ? 138.954 162.260 115.653 1.00 56.37  ?  704 VAL B CA  1 
ATOM   10671 C C   . VAL B 1 715 ? 137.568 161.973 115.133 1.00 56.37  ?  704 VAL B C   1 
ATOM   10672 O O   . VAL B 1 715 ? 136.589 162.251 115.810 1.00 56.37  ?  704 VAL B O   1 
ATOM   10673 C CB  . VAL B 1 715 ? 139.203 161.514 116.970 1.00 56.37  ?  704 VAL B CB  1 
ATOM   10674 C CG1 . VAL B 1 715 ? 139.117 160.012 116.755 1.00 56.37  ?  704 VAL B CG1 1 
ATOM   10675 C CG2 . VAL B 1 715 ? 140.553 161.899 117.550 1.00 56.37  ?  704 VAL B CG2 1 
ATOM   10676 N N   . LYS B 1 716 ? 137.473 161.421 113.931 1.00 54.00  ?  705 LYS B N   1 
ATOM   10677 C CA  . LYS B 1 716 ? 136.173 161.198 113.312 1.00 54.00  ?  705 LYS B CA  1 
ATOM   10678 C C   . LYS B 1 716 ? 135.930 159.744 112.970 1.00 54.00  ?  705 LYS B C   1 
ATOM   10679 O O   . LYS B 1 716 ? 136.852 158.942 112.983 1.00 54.00  ?  705 LYS B O   1 
ATOM   10680 C CB  . LYS B 1 716 ? 136.062 162.036 112.040 1.00 54.00  ?  705 LYS B CB  1 
ATOM   10681 C CG  . LYS B 1 716 ? 136.682 163.417 112.143 1.00 54.00  ?  705 LYS B CG  1 
ATOM   10682 C CD  . LYS B 1 716 ? 136.839 164.033 110.765 1.00 54.00  ?  705 LYS B CD  1 
ATOM   10683 C CE  . LYS B 1 716 ? 137.753 165.244 110.803 1.00 54.00  ?  705 LYS B CE  1 
ATOM   10684 N NZ  . LYS B 1 716 ? 138.001 165.798 109.444 1.00 54.00  1  705 LYS B NZ  1 
ATOM   10685 N N   . SER B 1 717 ? 134.688 159.400 112.667 1.00 52.70  ?  706 SER B N   1 
ATOM   10686 C CA  . SER B 1 717 ? 134.339 158.024 112.317 1.00 52.70  ?  706 SER B CA  1 
ATOM   10687 C C   . SER B 1 717 ? 134.897 157.573 110.960 1.00 52.70  ?  706 SER B C   1 
ATOM   10688 O O   . SER B 1 717 ? 134.935 156.380 110.697 1.00 52.70  ?  706 SER B O   1 
ATOM   10689 C CB  . SER B 1 717 ? 132.817 157.857 112.377 1.00 52.70  ?  706 SER B CB  1 
ATOM   10690 O OG  . SER B 1 717 ? 132.168 158.755 111.497 1.00 52.70  ?  706 SER B OG  1 
ATOM   10691 N N   . SER B 1 718 ? 135.302 158.502 110.094 1.00 50.28  ?  707 SER B N   1 
ATOM   10692 C CA  . SER B 1 718 ? 135.936 158.159 108.831 1.00 50.28  ?  707 SER B CA  1 
ATOM   10693 C C   . SER B 1 718 ? 137.272 157.457 109.017 1.00 50.28  ?  707 SER B C   1 
ATOM   10694 O O   . SER B 1 718 ? 137.868 157.022 108.026 1.00 50.28  ?  707 SER B O   1 
ATOM   10695 C CB  . SER B 1 718 ? 136.141 159.417 107.989 1.00 50.28  ?  707 SER B CB  1 
ATOM   10696 O OG  . SER B 1 718 ? 134.967 160.206 107.970 1.00 50.28  ?  707 SER B OG  1 
ATOM   10697 N N   . ILE B 1 719 ? 137.761 157.344 110.255 1.00 46.45  ?  708 ILE B N   1 
ATOM   10698 C CA  . ILE B 1 719 ? 139.003 156.626 110.518 1.00 46.45  ?  708 ILE B CA  1 
ATOM   10699 C C   . ILE B 1 719 ? 138.799 155.127 110.634 1.00 46.45  ?  708 ILE B C   1 
ATOM   10700 O O   . ILE B 1 719 ? 139.781 154.383 110.673 1.00 46.45  ?  708 ILE B O   1 
ATOM   10701 C CB  . ILE B 1 719 ? 139.676 157.137 111.805 1.00 46.45  ?  708 ILE B CB  1 
ATOM   10702 C CG1 . ILE B 1 719 ? 139.007 156.538 113.035 1.00 46.45  ?  708 ILE B CG1 1 
ATOM   10703 C CG2 . ILE B 1 719 ? 139.614 158.643 111.871 1.00 46.45  ?  708 ILE B CG2 1 
ATOM   10704 C CD1 . ILE B 1 719 ? 139.700 156.880 114.316 1.00 46.45  ?  708 ILE B CD1 1 
ATOM   10705 N N   . PHE B 1 720 ? 137.558 154.662 110.689 1.00 46.52  ?  709 PHE B N   1 
ATOM   10706 C CA  . PHE B 1 720 ? 137.264 153.240 110.792 1.00 46.52  ?  709 PHE B CA  1 
ATOM   10707 C C   . PHE B 1 720 ? 137.059 152.666 109.398 1.00 46.52  ?  709 PHE B C   1 
ATOM   10708 O O   . PHE B 1 720 ? 136.227 153.164 108.635 1.00 46.52  ?  709 PHE B O   1 
ATOM   10709 C CB  . PHE B 1 720 ? 136.027 153.001 111.651 1.00 46.52  ?  709 PHE B CB  1 
ATOM   10710 C CG  . PHE B 1 720 ? 136.302 152.984 113.118 1.00 46.52  ?  709 PHE B CG  1 
ATOM   10711 C CD1 . PHE B 1 720 ? 136.350 151.793 113.809 1.00 46.52  ?  709 PHE B CD1 1 
ATOM   10712 C CD2 . PHE B 1 720 ? 136.505 154.157 113.809 1.00 46.52  ?  709 PHE B CD2 1 
ATOM   10713 C CE1 . PHE B 1 720 ? 136.599 151.774 115.155 1.00 46.52  ?  709 PHE B CE1 1 
ATOM   10714 C CE2 . PHE B 1 720 ? 136.756 154.141 115.155 1.00 46.52  ?  709 PHE B CE2 1 
ATOM   10715 C CZ  . PHE B 1 720 ? 136.803 152.948 115.827 1.00 46.52  ?  709 PHE B CZ  1 
ATOM   10716 N N   . PHE B 1 721 ? 137.817 151.626 109.072 1.00 45.44  ?  710 PHE B N   1 
ATOM   10717 C CA  . PHE B 1 721 ? 137.680 150.911 107.816 1.00 45.44  ?  710 PHE B CA  1 
ATOM   10718 C C   . PHE B 1 721 ? 137.286 149.471 108.099 1.00 45.44  ?  710 PHE B C   1 
ATOM   10719 O O   . PHE B 1 721 ? 137.172 149.049 109.251 1.00 45.44  ?  710 PHE B O   1 
ATOM   10720 C CB  . PHE B 1 721 ? 138.971 150.981 106.995 1.00 45.44  ?  710 PHE B CB  1 
ATOM   10721 C CG  . PHE B 1 721 ? 139.051 152.187 106.115 1.00 45.44  ?  710 PHE B CG  1 
ATOM   10722 C CD1 . PHE B 1 721 ? 138.896 152.074 104.752 1.00 45.44  ?  710 PHE B CD1 1 
ATOM   10723 C CD2 . PHE B 1 721 ? 139.251 153.437 106.656 1.00 45.44  ?  710 PHE B CD2 1 
ATOM   10724 C CE1 . PHE B 1 721 ? 138.952 153.179 103.950 1.00 45.44  ?  710 PHE B CE1 1 
ATOM   10725 C CE2 . PHE B 1 721 ? 139.307 154.544 105.853 1.00 45.44  ?  710 PHE B CE2 1 
ATOM   10726 C CZ  . PHE B 1 721 ? 139.158 154.412 104.501 1.00 45.44  ?  710 PHE B CZ  1 
ATOM   10727 N N   . LEU B 1 722 ? 137.010 148.696 107.066 1.00 46.22  ?  711 LEU B N   1 
ATOM   10728 C CA  . LEU B 1 722 ? 136.555 147.332 107.306 1.00 46.22  ?  711 LEU B CA  1 
ATOM   10729 C C   . LEU B 1 722 ? 137.717 146.413 107.620 1.00 46.22  ?  711 LEU B C   1 
ATOM   10730 O O   . LEU B 1 722 ? 137.672 145.667 108.588 1.00 46.22  ?  711 LEU B O   1 
ATOM   10731 C CB  . LEU B 1 722 ? 135.761 146.791 106.115 1.00 46.22  ?  711 LEU B CB  1 
ATOM   10732 C CG  . LEU B 1 722 ? 134.399 147.428 105.840 1.00 46.22  ?  711 LEU B CG  1 
ATOM   10733 C CD1 . LEU B 1 722 ? 133.667 146.632 104.771 1.00 46.22  ?  711 LEU B CD1 1 
ATOM   10734 C CD2 . LEU B 1 722 ? 133.575 147.486 107.115 1.00 46.22  ?  711 LEU B CD2 1 
ATOM   10735 N N   . THR B 1 723 ? 138.766 146.480 106.820 1.00 44.77  ?  712 THR B N   1 
ATOM   10736 C CA  . THR B 1 723 ? 139.905 145.598 106.997 1.00 44.77  ?  712 THR B CA  1 
ATOM   10737 C C   . THR B 1 723 ? 141.189 146.354 106.806 1.00 44.77  ?  712 THR B C   1 
ATOM   10738 O O   . THR B 1 723 ? 141.168 147.525 106.445 1.00 44.77  ?  712 THR B O   1 
ATOM   10739 C CB  . THR B 1 723 ? 139.865 144.433 105.983 1.00 44.77  ?  712 THR B CB  1 
ATOM   10740 O OG1 . THR B 1 723 ? 140.022 144.945 104.655 1.00 44.77  ?  712 THR B OG1 1 
ATOM   10741 C CG2 . THR B 1 723 ? 138.551 143.676 106.078 1.00 44.77  ?  712 THR B CG2 1 
ATOM   10742 N N   . ILE B 1 724 ? 142.312 145.696 107.044 1.00 42.54  ?  713 ILE B N   1 
ATOM   10743 C CA  . ILE B 1 724 ? 143.606 146.318 106.837 1.00 42.54  ?  713 ILE B CA  1 
ATOM   10744 C C   . ILE B 1 724 ? 143.795 146.667 105.373 1.00 42.54  ?  713 ILE B C   1 
ATOM   10745 O O   . ILE B 1 724 ? 144.239 147.761 105.055 1.00 42.54  ?  713 ILE B O   1 
ATOM   10746 C CB  . ILE B 1 724 ? 144.751 145.391 107.309 1.00 42.54  ?  713 ILE B CB  1 
ATOM   10747 C CG1 . ILE B 1 724 ? 144.621 145.090 108.803 1.00 42.54  ?  713 ILE B CG1 1 
ATOM   10748 C CG2 . ILE B 1 724 ? 146.109 146.003 107.000 1.00 42.54  ?  713 ILE B CG2 1 
ATOM   10749 C CD1 . ILE B 1 724 ? 145.625 144.081 109.312 1.00 42.54  ?  713 ILE B CD1 1 
ATOM   10750 N N   . HIS B 1 725 ? 143.443 145.753 104.479 1.00 44.61  ?  714 HIS B N   1 
ATOM   10751 C CA  . HIS B 1 725 ? 143.649 145.979 103.053 1.00 44.61  ?  714 HIS B CA  1 
ATOM   10752 C C   . HIS B 1 725 ? 142.804 147.132 102.524 1.00 44.61  ?  714 HIS B C   1 
ATOM   10753 O O   . HIS B 1 725 ? 143.234 147.837 101.623 1.00 44.61  ?  714 HIS B O   1 
ATOM   10754 C CB  . HIS B 1 725 ? 143.398 144.683 102.266 1.00 44.61  ?  714 HIS B CB  1 
ATOM   10755 C CG  . HIS B 1 725 ? 144.060 144.652 100.926 1.00 44.61  ?  714 HIS B CG  1 
ATOM   10756 N ND1 . HIS B 1 725 ? 143.359 144.493 99.752  1.00 44.61  ?  714 HIS B ND1 1 
ATOM   10757 C CD2 . HIS B 1 725 ? 145.362 144.768 100.575 1.00 44.61  ?  714 HIS B CD2 1 
ATOM   10758 C CE1 . HIS B 1 725 ? 144.200 144.504 98.735  1.00 44.61  ?  714 HIS B CE1 1 
ATOM   10759 N NE2 . HIS B 1 725 ? 145.422 144.673 99.207  1.00 44.61  ?  714 HIS B NE2 1 
ATOM   10760 N N   . ASP B 1 726 ? 141.615 147.336 103.077 1.00 47.13  ?  715 ASP B N   1 
ATOM   10761 C CA  . ASP B 1 726 ? 140.786 148.468 102.682 1.00 47.13  ?  715 ASP B CA  1 
ATOM   10762 C C   . ASP B 1 726 ? 141.504 149.752 103.013 1.00 47.13  ?  715 ASP B C   1 
ATOM   10763 O O   . ASP B 1 726 ? 141.606 150.637 102.175 1.00 47.13  ?  715 ASP B O   1 
ATOM   10764 C CB  . ASP B 1 726 ? 139.439 148.428 103.403 1.00 47.13  ?  715 ASP B CB  1 
ATOM   10765 C CG  . ASP B 1 726 ? 138.475 147.441 102.792 1.00 47.13  ?  715 ASP B CG  1 
ATOM   10766 O OD1 . ASP B 1 726 ? 138.238 146.387 103.412 1.00 47.13  ?  715 ASP B OD1 1 
ATOM   10767 O OD2 . ASP B 1 726 ? 137.949 147.720 101.698 1.00 47.13  -1 715 ASP B OD2 1 
ATOM   10768 N N   . ALA B 1 727 ? 141.984 149.870 104.235 1.00 45.24  ?  716 ALA B N   1 
ATOM   10769 C CA  . ALA B 1 727 ? 142.750 151.034 104.660 1.00 45.24  ?  716 ALA B CA  1 
ATOM   10770 C C   . ALA B 1 727 ? 143.992 151.222 103.805 1.00 45.24  ?  716 ALA B C   1 
ATOM   10771 O O   . ALA B 1 727 ? 144.328 152.350 103.443 1.00 45.24  ?  716 ALA B O   1 
ATOM   10772 C CB  . ALA B 1 727 ? 143.131 150.902 106.131 1.00 45.24  ?  716 ALA B CB  1 
ATOM   10773 N N   . VAL B 1 728 ? 144.681 150.132 103.463 1.00 46.40  ?  717 VAL B N   1 
ATOM   10774 C CA  . VAL B 1 728 ? 145.916 150.243 102.692 1.00 46.40  ?  717 VAL B CA  1 
ATOM   10775 C C   . VAL B 1 728 ? 145.634 150.751 101.283 1.00 46.40  ?  717 VAL B C   1 
ATOM   10776 O O   . VAL B 1 728 ? 146.376 151.584 100.752 1.00 46.40  ?  717 VAL B O   1 
ATOM   10777 C CB  . VAL B 1 728 ? 146.652 148.893 102.677 1.00 46.40  ?  717 VAL B CB  1 
ATOM   10778 C CG1 . VAL B 1 728 ? 147.710 148.879 101.597 1.00 46.40  ?  717 VAL B CG1 1 
ATOM   10779 C CG2 . VAL B 1 728 ? 147.275 148.629 104.026 1.00 46.40  ?  717 VAL B CG2 1 
ATOM   10780 N N   . LEU B 1 729 ? 144.560 150.273 100.656 1.00 49.82  ?  718 LEU B N   1 
ATOM   10781 C CA  . LEU B 1 729 ? 144.227 150.744 99.317  1.00 49.82  ?  718 LEU B CA  1 
ATOM   10782 C C   . LEU B 1 729 ? 143.757 152.192 99.345  1.00 49.82  ?  718 LEU B C   1 
ATOM   10783 O O   . LEU B 1 729 ? 144.065 152.972 98.432  1.00 49.82  ?  718 LEU B O   1 
ATOM   10784 C CB  . LEU B 1 729 ? 143.164 149.844 98.697  1.00 49.82  ?  718 LEU B CB  1 
ATOM   10785 C CG  . LEU B 1 729 ? 143.636 148.457 98.280  1.00 49.82  ?  718 LEU B CG  1 
ATOM   10786 C CD1 . LEU B 1 729 ? 142.464 147.649 97.788  1.00 49.82  ?  718 LEU B CD1 1 
ATOM   10787 C CD2 . LEU B 1 729 ? 144.702 148.556 97.216  1.00 49.82  ?  718 LEU B CD2 1 
ATOM   10788 N N   . HIS B 1 730 ? 143.012 152.572 100.386 1.00 51.18  ?  719 HIS B N   1 
ATOM   10789 C CA  . HIS B 1 730 ? 142.653 153.972 100.568 1.00 51.18  ?  719 HIS B CA  1 
ATOM   10790 C C   . HIS B 1 730 ? 143.894 154.845 100.698 1.00 51.18  ?  719 HIS B C   1 
ATOM   10791 O O   . HIS B 1 730 ? 143.975 155.921 100.095 1.00 51.18  ?  719 HIS B O   1 
ATOM   10792 C CB  . HIS B 1 730 ? 141.769 154.117 101.802 1.00 51.18  ?  719 HIS B CB  1 
ATOM   10793 C CG  . HIS B 1 730 ? 141.223 155.494 101.996 1.00 51.18  ?  719 HIS B CG  1 
ATOM   10794 N ND1 . HIS B 1 730 ? 140.352 156.080 101.108 1.00 51.18  ?  719 HIS B ND1 1 
ATOM   10795 C CD2 . HIS B 1 730 ? 141.422 156.399 102.981 1.00 51.18  ?  719 HIS B CD2 1 
ATOM   10796 C CE1 . HIS B 1 730 ? 140.036 157.287 101.536 1.00 51.18  ?  719 HIS B CE1 1 
ATOM   10797 N NE2 . HIS B 1 730 ? 140.674 157.506 102.671 1.00 51.18  ?  719 HIS B NE2 1 
ATOM   10798 N N   . ILE B 1 731 ? 144.866 154.396 101.490 1.00 51.32  ?  720 ILE B N   1 
ATOM   10799 C CA  . ILE B 1 731 ? 146.111 155.137 101.666 1.00 51.32  ?  720 ILE B CA  1 
ATOM   10800 C C   . ILE B 1 731 ? 146.831 155.287 100.336 1.00 51.32  ?  720 ILE B C   1 
ATOM   10801 O O   . ILE B 1 731 ? 147.329 156.365 99.996  1.00 51.32  ?  720 ILE B O   1 
ATOM   10802 C CB  . ILE B 1 731 ? 147.000 154.434 102.705 1.00 51.32  ?  720 ILE B CB  1 
ATOM   10803 C CG1 . ILE B 1 731 ? 146.394 154.560 104.096 1.00 51.32  ?  720 ILE B CG1 1 
ATOM   10804 C CG2 . ILE B 1 731 ? 148.393 155.004 102.677 1.00 51.32  ?  720 ILE B CG2 1 
ATOM   10805 C CD1 . ILE B 1 731 ? 146.861 153.508 105.049 1.00 51.32  ?  720 ILE B CD1 1 
ATOM   10806 N N   . LEU B 1 732 ? 146.900 154.204 99.564  1.00 57.27  ?  721 LEU B N   1 
ATOM   10807 C CA  . LEU B 1 732 ? 147.611 154.257 98.293  1.00 57.27  ?  721 LEU B CA  1 
ATOM   10808 C C   . LEU B 1 732 ? 146.947 155.214 97.313  1.00 57.27  ?  721 LEU B C   1 
ATOM   10809 O O   . LEU B 1 732 ? 147.644 155.974 96.633  1.00 57.27  ?  721 LEU B O   1 
ATOM   10810 C CB  . LEU B 1 732 ? 147.720 152.860 97.686  1.00 57.27  ?  721 LEU B CB  1 
ATOM   10811 C CG  . LEU B 1 732 ? 148.615 151.877 98.442  1.00 57.27  ?  721 LEU B CG  1 
ATOM   10812 C CD1 . LEU B 1 732 ? 148.799 150.597 97.655  1.00 57.27  ?  721 LEU B CD1 1 
ATOM   10813 C CD2 . LEU B 1 732 ? 149.959 152.507 98.760  1.00 57.27  ?  721 LEU B CD2 1 
ATOM   10814 N N   . MET B 1 733 ? 145.615 155.216 97.234  1.00 64.82  ?  722 MET B N   1 
ATOM   10815 C CA  . MET B 1 733 ? 144.959 156.135 96.305  1.00 64.82  ?  722 MET B CA  1 
ATOM   10816 C C   . MET B 1 733 ? 145.070 157.580 96.783  1.00 64.82  ?  722 MET B C   1 
ATOM   10817 O O   . MET B 1 733 ? 145.308 158.490 95.977  1.00 64.82  ?  722 MET B O   1 
ATOM   10818 C CB  . MET B 1 733 ? 143.502 155.730 96.079  1.00 64.82  ?  722 MET B CB  1 
ATOM   10819 C CG  . MET B 1 733 ? 142.614 155.738 97.302  1.00 64.82  ?  722 MET B CG  1 
ATOM   10820 S SD  . MET B 1 733 ? 141.131 154.743 97.053  1.00 64.82  ?  722 MET B SD  1 
ATOM   10821 C CE  . MET B 1 733 ? 141.797 153.370 96.113  1.00 64.82  ?  722 MET B CE  1 
ATOM   10822 N N   . LYS B 1 734 ? 144.929 157.815 98.093  1.00 64.65  ?  723 LYS B N   1 
ATOM   10823 C CA  . LYS B 1 734 ? 145.176 159.147 98.639  1.00 64.65  ?  723 LYS B CA  1 
ATOM   10824 C C   . LYS B 1 734 ? 146.563 159.649 98.267  1.00 64.65  ?  723 LYS B C   1 
ATOM   10825 O O   . LYS B 1 734 ? 146.724 160.792 97.823  1.00 64.65  ?  723 LYS B O   1 
ATOM   10826 C CB  . LYS B 1 734 ? 145.029 159.137 100.158 1.00 64.65  ?  723 LYS B CB  1 
ATOM   10827 C CG  . LYS B 1 734 ? 143.666 159.510 100.675 1.00 64.65  ?  723 LYS B CG  1 
ATOM   10828 C CD  . LYS B 1 734 ? 143.751 159.988 102.115 1.00 64.65  ?  723 LYS B CD  1 
ATOM   10829 C CE  . LYS B 1 734 ? 144.649 161.210 102.238 1.00 64.65  ?  723 LYS B CE  1 
ATOM   10830 N NZ  . LYS B 1 734 ? 144.741 161.716 103.636 1.00 64.65  1  723 LYS B NZ  1 
ATOM   10831 N N   . LYS B 1 735 ? 147.581 158.804 98.433  1.00 66.60  ?  724 LYS B N   1 
ATOM   10832 C CA  . LYS B 1 735 ? 148.952 159.255 98.240  1.00 66.60  ?  724 LYS B CA  1 
ATOM   10833 C C   . LYS B 1 735 ? 149.281 159.420 96.764  1.00 66.60  ?  724 LYS B C   1 
ATOM   10834 O O   . LYS B 1 735 ? 150.051 160.310 96.392  1.00 66.60  ?  724 LYS B O   1 
ATOM   10835 C CB  . LYS B 1 735 ? 149.921 158.289 98.913  1.00 66.60  ?  724 LYS B CB  1 
ATOM   10836 C CG  . LYS B 1 735 ? 149.822 158.295 100.425 1.00 66.60  ?  724 LYS B CG  1 
ATOM   10837 C CD  . LYS B 1 735 ? 149.753 159.713 100.969 1.00 66.60  ?  724 LYS B CD  1 
ATOM   10838 C CE  . LYS B 1 735 ? 148.922 159.778 102.241 1.00 66.60  ?  724 LYS B CE  1 
ATOM   10839 N NZ  . LYS B 1 735 ? 149.011 161.112 102.891 1.00 66.60  1  724 LYS B NZ  1 
ATOM   10840 N N   . ASP B 1 736 ? 148.697 158.592 95.893  1.00 73.99  ?  725 ASP B N   1 
ATOM   10841 C CA  . ASP B 1 736 ? 148.937 158.800 94.468  1.00 73.99  ?  725 ASP B CA  1 
ATOM   10842 C C   . ASP B 1 736 ? 148.228 160.054 93.972  1.00 73.99  ?  725 ASP B C   1 
ATOM   10843 O O   . ASP B 1 736 ? 148.753 160.762 93.106  1.00 73.99  ?  725 ASP B O   1 
ATOM   10844 C CB  . ASP B 1 736 ? 148.547 157.548 93.663  1.00 73.99  ?  725 ASP B CB  1 
ATOM   10845 C CG  . ASP B 1 736 ? 147.037 157.315 93.559  1.00 73.99  ?  725 ASP B CG  1 
ATOM   10846 O OD1 . ASP B 1 736 ? 146.242 158.271 93.458  1.00 73.99  ?  725 ASP B OD1 1 
ATOM   10847 O OD2 . ASP B 1 736 ? 146.642 156.131 93.579  1.00 73.99  -1 725 ASP B OD2 1 
HETATM 10848 S S   . SO4 C 2 .   ? 146.317 166.997 148.594 1.00 61.42  ?  801 SO4 A S   1 
HETATM 10849 O O1  . SO4 C 2 .   ? 146.224 167.672 147.309 1.00 61.42  ?  801 SO4 A O1  1 
HETATM 10850 O O2  . SO4 C 2 .   ? 146.941 165.695 148.412 1.00 61.42  ?  801 SO4 A O2  1 
HETATM 10851 O O3  . SO4 C 2 .   ? 144.979 166.824 149.141 1.00 61.42  -1 801 SO4 A O3  1 
HETATM 10852 O O4  . SO4 C 2 .   ? 147.051 167.843 149.524 1.00 61.42  ?  801 SO4 A O4  1 
HETATM 10853 S S   . SO4 D 2 .   ? 133.318 112.560 148.608 1.00 61.42  ?  801 SO4 B S   1 
HETATM 10854 O O1  . SO4 D 2 .   ? 132.784 113.896 148.371 1.00 61.42  ?  801 SO4 B O1  1 
HETATM 10855 O O2  . SO4 D 2 .   ? 133.377 111.834 147.345 1.00 61.42  ?  801 SO4 B O2  1 
HETATM 10856 O O3  . SO4 D 2 .   ? 132.442 111.847 149.528 1.00 61.42  -1 801 SO4 B O3  1 
HETATM 10857 O O4  . SO4 D 2 .   ? 134.655 112.659 149.184 1.00 61.42  ?  801 SO4 B O4  1 
# 
