data_8X1S
# 
_entry.id   8X1S 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8X1S         pdb_00008x1s 10.2210/pdb8x1s/pdb 
WWPDB D_1300042454 ?            ?                   
EMDB  EMD-38000    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-05-14 ? 
2 'EM metadata'     1 0 2025-05-14 ? 
3 FSC               1 0 2025-05-14 ? 
4 'Half map'        1 0 2025-05-14 1 
5 'Half map'        1 0 2025-05-14 2 
6 Image             1 0 2025-05-14 ? 
7 Mask              1 0 2025-05-14 1 
8 'Primary map'     1 0 2025-05-14 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 Mask              repository 'Initial release' ? ? 
8 8 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8X1S 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of human DRA (SLC26A3) bound with tenidap' 
_pdbx_database_related.db_id          EMD-38000 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              zyq_lab@fudan.edu.cn 
_pdbx_contact_author.name_first         Yanqing 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-7654-1645 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yang, X.'  1 0000-0001-8393-325X 
'Zhang, Y.' 2 0000-0001-7654-1645 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cryo-EM structure of human DRA (SLC26A3) bound with tenidap' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yang, X.'  1 0000-0001-8393-325X 
primary 'Zhang, Y.' 2 0000-0001-7654-1645 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Chloride anion exchanger'                                          85877.844 2 ? ? ? ? 
2 non-polymer syn 'CHLORIDE ION'                                                      35.453    2 ? ? ? ? 
3 non-polymer syn 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE                           510.708   2 ? ? ? ? 
4 non-polymer syn 5-chloranyl-2-oxidanyl-3-thiophen-2-ylcarbonyl-indole-1-carboxamide 320.751   2 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        DRA 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MDYKDDDDKGTMIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRL
KEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAV
PDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFI
FQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDF
KNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFR
GFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDC
LIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANI
GFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHI
DWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIF
FLTIHDAVLHILMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MDYKDDDDKGTMIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRL
KEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAV
PDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFI
FQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDF
KNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFR
GFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDC
LIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANI
GFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHI
DWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIF
FLTIHDAVLHILMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'CHLORIDE ION'                                                      CL  
3 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE                           LPE 
4 5-chloranyl-2-oxidanyl-3-thiophen-2-ylcarbonyl-indole-1-carboxamide I2U 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASP n 
1 3   TYR n 
1 4   LYS n 
1 5   ASP n 
1 6   ASP n 
1 7   ASP n 
1 8   ASP n 
1 9   LYS n 
1 10  GLY n 
1 11  THR n 
1 12  MET n 
1 13  ILE n 
1 14  GLU n 
1 15  PRO n 
1 16  PHE n 
1 17  GLY n 
1 18  ASN n 
1 19  GLN n 
1 20  TYR n 
1 21  ILE n 
1 22  VAL n 
1 23  ALA n 
1 24  ARG n 
1 25  PRO n 
1 26  VAL n 
1 27  TYR n 
1 28  SER n 
1 29  THR n 
1 30  ASN n 
1 31  ALA n 
1 32  PHE n 
1 33  GLU n 
1 34  GLU n 
1 35  ASN n 
1 36  HIS n 
1 37  LYS n 
1 38  LYS n 
1 39  THR n 
1 40  GLY n 
1 41  ARG n 
1 42  HIS n 
1 43  HIS n 
1 44  LYS n 
1 45  THR n 
1 46  PHE n 
1 47  LEU n 
1 48  ASP n 
1 49  HIS n 
1 50  LEU n 
1 51  LYS n 
1 52  VAL n 
1 53  CYS n 
1 54  CYS n 
1 55  SER n 
1 56  CYS n 
1 57  SER n 
1 58  PRO n 
1 59  GLN n 
1 60  LYS n 
1 61  ALA n 
1 62  LYS n 
1 63  ARG n 
1 64  ILE n 
1 65  VAL n 
1 66  LEU n 
1 67  SER n 
1 68  LEU n 
1 69  PHE n 
1 70  PRO n 
1 71  ILE n 
1 72  ALA n 
1 73  SER n 
1 74  TRP n 
1 75  LEU n 
1 76  PRO n 
1 77  ALA n 
1 78  TYR n 
1 79  ARG n 
1 80  LEU n 
1 81  LYS n 
1 82  GLU n 
1 83  TRP n 
1 84  LEU n 
1 85  LEU n 
1 86  SER n 
1 87  ASP n 
1 88  ILE n 
1 89  VAL n 
1 90  SER n 
1 91  GLY n 
1 92  ILE n 
1 93  SER n 
1 94  THR n 
1 95  GLY n 
1 96  ILE n 
1 97  VAL n 
1 98  ALA n 
1 99  VAL n 
1 100 LEU n 
1 101 GLN n 
1 102 GLY n 
1 103 LEU n 
1 104 ALA n 
1 105 PHE n 
1 106 ALA n 
1 107 LEU n 
1 108 LEU n 
1 109 VAL n 
1 110 ASP n 
1 111 ILE n 
1 112 PRO n 
1 113 PRO n 
1 114 VAL n 
1 115 TYR n 
1 116 GLY n 
1 117 LEU n 
1 118 TYR n 
1 119 ALA n 
1 120 SER n 
1 121 PHE n 
1 122 PHE n 
1 123 PRO n 
1 124 ALA n 
1 125 ILE n 
1 126 ILE n 
1 127 TYR n 
1 128 LEU n 
1 129 PHE n 
1 130 PHE n 
1 131 GLY n 
1 132 THR n 
1 133 SER n 
1 134 ARG n 
1 135 HIS n 
1 136 ILE n 
1 137 SER n 
1 138 VAL n 
1 139 GLY n 
1 140 PRO n 
1 141 PHE n 
1 142 PRO n 
1 143 ILE n 
1 144 LEU n 
1 145 SER n 
1 146 MET n 
1 147 MET n 
1 148 VAL n 
1 149 GLY n 
1 150 LEU n 
1 151 ALA n 
1 152 VAL n 
1 153 SER n 
1 154 GLY n 
1 155 ALA n 
1 156 VAL n 
1 157 SER n 
1 158 LYS n 
1 159 ALA n 
1 160 VAL n 
1 161 PRO n 
1 162 ASP n 
1 163 ARG n 
1 164 ASN n 
1 165 ALA n 
1 166 THR n 
1 167 THR n 
1 168 LEU n 
1 169 GLY n 
1 170 LEU n 
1 171 PRO n 
1 172 ASN n 
1 173 ASN n 
1 174 SER n 
1 175 ASN n 
1 176 ASN n 
1 177 SER n 
1 178 SER n 
1 179 LEU n 
1 180 LEU n 
1 181 ASP n 
1 182 ASP n 
1 183 GLU n 
1 184 ARG n 
1 185 VAL n 
1 186 ARG n 
1 187 VAL n 
1 188 ALA n 
1 189 ALA n 
1 190 ALA n 
1 191 ALA n 
1 192 SER n 
1 193 VAL n 
1 194 THR n 
1 195 VAL n 
1 196 LEU n 
1 197 SER n 
1 198 GLY n 
1 199 ILE n 
1 200 ILE n 
1 201 GLN n 
1 202 LEU n 
1 203 ALA n 
1 204 PHE n 
1 205 GLY n 
1 206 ILE n 
1 207 LEU n 
1 208 ARG n 
1 209 ILE n 
1 210 GLY n 
1 211 PHE n 
1 212 VAL n 
1 213 VAL n 
1 214 ILE n 
1 215 TYR n 
1 216 LEU n 
1 217 SER n 
1 218 GLU n 
1 219 SER n 
1 220 LEU n 
1 221 ILE n 
1 222 SER n 
1 223 GLY n 
1 224 PHE n 
1 225 THR n 
1 226 THR n 
1 227 ALA n 
1 228 ALA n 
1 229 ALA n 
1 230 VAL n 
1 231 HIS n 
1 232 VAL n 
1 233 LEU n 
1 234 VAL n 
1 235 SER n 
1 236 GLN n 
1 237 LEU n 
1 238 LYS n 
1 239 PHE n 
1 240 ILE n 
1 241 PHE n 
1 242 GLN n 
1 243 LEU n 
1 244 THR n 
1 245 VAL n 
1 246 PRO n 
1 247 SER n 
1 248 HIS n 
1 249 THR n 
1 250 ASP n 
1 251 PRO n 
1 252 VAL n 
1 253 SER n 
1 254 ILE n 
1 255 PHE n 
1 256 LYS n 
1 257 VAL n 
1 258 LEU n 
1 259 TYR n 
1 260 SER n 
1 261 VAL n 
1 262 PHE n 
1 263 SER n 
1 264 GLN n 
1 265 ILE n 
1 266 GLU n 
1 267 LYS n 
1 268 THR n 
1 269 ASN n 
1 270 ILE n 
1 271 ALA n 
1 272 ASP n 
1 273 LEU n 
1 274 VAL n 
1 275 THR n 
1 276 ALA n 
1 277 LEU n 
1 278 ILE n 
1 279 VAL n 
1 280 LEU n 
1 281 LEU n 
1 282 VAL n 
1 283 VAL n 
1 284 SER n 
1 285 ILE n 
1 286 VAL n 
1 287 LYS n 
1 288 GLU n 
1 289 ILE n 
1 290 ASN n 
1 291 GLN n 
1 292 ARG n 
1 293 PHE n 
1 294 LYS n 
1 295 ASP n 
1 296 LYS n 
1 297 LEU n 
1 298 PRO n 
1 299 VAL n 
1 300 PRO n 
1 301 ILE n 
1 302 PRO n 
1 303 ILE n 
1 304 GLU n 
1 305 PHE n 
1 306 ILE n 
1 307 MET n 
1 308 THR n 
1 309 VAL n 
1 310 ILE n 
1 311 ALA n 
1 312 ALA n 
1 313 GLY n 
1 314 VAL n 
1 315 SER n 
1 316 TYR n 
1 317 GLY n 
1 318 CYS n 
1 319 ASP n 
1 320 PHE n 
1 321 LYS n 
1 322 ASN n 
1 323 ARG n 
1 324 PHE n 
1 325 LYS n 
1 326 VAL n 
1 327 ALA n 
1 328 VAL n 
1 329 VAL n 
1 330 GLY n 
1 331 ASP n 
1 332 MET n 
1 333 ASN n 
1 334 PRO n 
1 335 GLY n 
1 336 PHE n 
1 337 GLN n 
1 338 PRO n 
1 339 PRO n 
1 340 ILE n 
1 341 THR n 
1 342 PRO n 
1 343 ASP n 
1 344 VAL n 
1 345 GLU n 
1 346 THR n 
1 347 PHE n 
1 348 GLN n 
1 349 ASN n 
1 350 THR n 
1 351 VAL n 
1 352 GLY n 
1 353 ASP n 
1 354 CYS n 
1 355 PHE n 
1 356 GLY n 
1 357 ILE n 
1 358 ALA n 
1 359 MET n 
1 360 VAL n 
1 361 ALA n 
1 362 PHE n 
1 363 ALA n 
1 364 VAL n 
1 365 ALA n 
1 366 PHE n 
1 367 SER n 
1 368 VAL n 
1 369 ALA n 
1 370 SER n 
1 371 VAL n 
1 372 TYR n 
1 373 SER n 
1 374 LEU n 
1 375 LYS n 
1 376 TYR n 
1 377 ASP n 
1 378 TYR n 
1 379 PRO n 
1 380 LEU n 
1 381 ASP n 
1 382 GLY n 
1 383 ASN n 
1 384 GLN n 
1 385 GLU n 
1 386 LEU n 
1 387 ILE n 
1 388 ALA n 
1 389 LEU n 
1 390 GLY n 
1 391 LEU n 
1 392 GLY n 
1 393 ASN n 
1 394 ILE n 
1 395 VAL n 
1 396 CYS n 
1 397 GLY n 
1 398 VAL n 
1 399 PHE n 
1 400 ARG n 
1 401 GLY n 
1 402 PHE n 
1 403 ALA n 
1 404 GLY n 
1 405 SER n 
1 406 THR n 
1 407 ALA n 
1 408 LEU n 
1 409 SER n 
1 410 ARG n 
1 411 SER n 
1 412 ALA n 
1 413 VAL n 
1 414 GLN n 
1 415 GLU n 
1 416 SER n 
1 417 THR n 
1 418 GLY n 
1 419 GLY n 
1 420 LYS n 
1 421 THR n 
1 422 GLN n 
1 423 ILE n 
1 424 ALA n 
1 425 GLY n 
1 426 LEU n 
1 427 ILE n 
1 428 GLY n 
1 429 ALA n 
1 430 ILE n 
1 431 ILE n 
1 432 VAL n 
1 433 LEU n 
1 434 ILE n 
1 435 VAL n 
1 436 VAL n 
1 437 LEU n 
1 438 ALA n 
1 439 ILE n 
1 440 GLY n 
1 441 PHE n 
1 442 LEU n 
1 443 LEU n 
1 444 ALA n 
1 445 PRO n 
1 446 LEU n 
1 447 GLN n 
1 448 LYS n 
1 449 SER n 
1 450 VAL n 
1 451 LEU n 
1 452 ALA n 
1 453 ALA n 
1 454 LEU n 
1 455 ALA n 
1 456 LEU n 
1 457 GLY n 
1 458 ASN n 
1 459 LEU n 
1 460 LYS n 
1 461 GLY n 
1 462 MET n 
1 463 LEU n 
1 464 MET n 
1 465 GLN n 
1 466 PHE n 
1 467 ALA n 
1 468 GLU n 
1 469 ILE n 
1 470 GLY n 
1 471 ARG n 
1 472 LEU n 
1 473 TRP n 
1 474 ARG n 
1 475 LYS n 
1 476 ASP n 
1 477 LYS n 
1 478 TYR n 
1 479 ASP n 
1 480 CYS n 
1 481 LEU n 
1 482 ILE n 
1 483 TRP n 
1 484 ILE n 
1 485 MET n 
1 486 THR n 
1 487 PHE n 
1 488 ILE n 
1 489 PHE n 
1 490 THR n 
1 491 ILE n 
1 492 VAL n 
1 493 LEU n 
1 494 GLY n 
1 495 LEU n 
1 496 GLY n 
1 497 LEU n 
1 498 GLY n 
1 499 LEU n 
1 500 ALA n 
1 501 ALA n 
1 502 SER n 
1 503 VAL n 
1 504 ALA n 
1 505 PHE n 
1 506 GLN n 
1 507 LEU n 
1 508 LEU n 
1 509 THR n 
1 510 ILE n 
1 511 VAL n 
1 512 PHE n 
1 513 ARG n 
1 514 THR n 
1 515 GLN n 
1 516 PHE n 
1 517 PRO n 
1 518 LYS n 
1 519 CYS n 
1 520 SER n 
1 521 THR n 
1 522 LEU n 
1 523 ALA n 
1 524 ASN n 
1 525 ILE n 
1 526 GLY n 
1 527 ARG n 
1 528 THR n 
1 529 ASN n 
1 530 ILE n 
1 531 TYR n 
1 532 LYS n 
1 533 ASN n 
1 534 LYS n 
1 535 LYS n 
1 536 ASP n 
1 537 TYR n 
1 538 TYR n 
1 539 ASP n 
1 540 MET n 
1 541 TYR n 
1 542 GLU n 
1 543 PRO n 
1 544 GLU n 
1 545 GLY n 
1 546 VAL n 
1 547 LYS n 
1 548 ILE n 
1 549 PHE n 
1 550 ARG n 
1 551 CYS n 
1 552 PRO n 
1 553 SER n 
1 554 PRO n 
1 555 ILE n 
1 556 TYR n 
1 557 PHE n 
1 558 ALA n 
1 559 ASN n 
1 560 ILE n 
1 561 GLY n 
1 562 PHE n 
1 563 PHE n 
1 564 ARG n 
1 565 ARG n 
1 566 LYS n 
1 567 LEU n 
1 568 ILE n 
1 569 ASP n 
1 570 ALA n 
1 571 VAL n 
1 572 GLY n 
1 573 PHE n 
1 574 SER n 
1 575 PRO n 
1 576 LEU n 
1 577 ARG n 
1 578 ILE n 
1 579 LEU n 
1 580 ARG n 
1 581 LYS n 
1 582 ARG n 
1 583 ASN n 
1 584 LYS n 
1 585 ALA n 
1 586 LEU n 
1 587 ARG n 
1 588 LYS n 
1 589 ILE n 
1 590 ARG n 
1 591 LYS n 
1 592 LEU n 
1 593 GLN n 
1 594 LYS n 
1 595 GLN n 
1 596 GLY n 
1 597 LEU n 
1 598 LEU n 
1 599 GLN n 
1 600 VAL n 
1 601 THR n 
1 602 PRO n 
1 603 LYS n 
1 604 GLY n 
1 605 PHE n 
1 606 ILE n 
1 607 CYS n 
1 608 THR n 
1 609 VAL n 
1 610 ASP n 
1 611 THR n 
1 612 ILE n 
1 613 LYS n 
1 614 ASP n 
1 615 SER n 
1 616 ASP n 
1 617 GLU n 
1 618 GLU n 
1 619 LEU n 
1 620 ASP n 
1 621 ASN n 
1 622 ASN n 
1 623 GLN n 
1 624 ILE n 
1 625 GLU n 
1 626 VAL n 
1 627 LEU n 
1 628 ASP n 
1 629 GLN n 
1 630 PRO n 
1 631 ILE n 
1 632 ASN n 
1 633 THR n 
1 634 THR n 
1 635 ASP n 
1 636 LEU n 
1 637 PRO n 
1 638 PHE n 
1 639 HIS n 
1 640 ILE n 
1 641 ASP n 
1 642 TRP n 
1 643 ASN n 
1 644 ASP n 
1 645 ASP n 
1 646 LEU n 
1 647 PRO n 
1 648 LEU n 
1 649 ASN n 
1 650 ILE n 
1 651 GLU n 
1 652 VAL n 
1 653 PRO n 
1 654 LYS n 
1 655 ILE n 
1 656 SER n 
1 657 LEU n 
1 658 HIS n 
1 659 SER n 
1 660 LEU n 
1 661 ILE n 
1 662 LEU n 
1 663 ASP n 
1 664 PHE n 
1 665 SER n 
1 666 ALA n 
1 667 VAL n 
1 668 SER n 
1 669 PHE n 
1 670 LEU n 
1 671 ASP n 
1 672 VAL n 
1 673 SER n 
1 674 SER n 
1 675 VAL n 
1 676 ARG n 
1 677 GLY n 
1 678 LEU n 
1 679 LYS n 
1 680 SER n 
1 681 ILE n 
1 682 LEU n 
1 683 GLN n 
1 684 GLU n 
1 685 PHE n 
1 686 ILE n 
1 687 ARG n 
1 688 ILE n 
1 689 LYS n 
1 690 VAL n 
1 691 ASP n 
1 692 VAL n 
1 693 TYR n 
1 694 ILE n 
1 695 VAL n 
1 696 GLY n 
1 697 THR n 
1 698 ASP n 
1 699 ASP n 
1 700 ASP n 
1 701 PHE n 
1 702 ILE n 
1 703 GLU n 
1 704 LYS n 
1 705 LEU n 
1 706 ASN n 
1 707 ARG n 
1 708 TYR n 
1 709 GLU n 
1 710 PHE n 
1 711 PHE n 
1 712 ASP n 
1 713 GLY n 
1 714 GLU n 
1 715 VAL n 
1 716 LYS n 
1 717 SER n 
1 718 SER n 
1 719 ILE n 
1 720 PHE n 
1 721 PHE n 
1 722 LEU n 
1 723 THR n 
1 724 ILE n 
1 725 HIS n 
1 726 ASP n 
1 727 ALA n 
1 728 VAL n 
1 729 LEU n 
1 730 HIS n 
1 731 ILE n 
1 732 LEU n 
1 733 MET n 
1 734 LYS n 
1 735 LYS n 
1 736 ASP n 
1 737 TYR n 
1 738 SER n 
1 739 THR n 
1 740 SER n 
1 741 LYS n 
1 742 PHE n 
1 743 ASN n 
1 744 PRO n 
1 745 SER n 
1 746 GLN n 
1 747 GLU n 
1 748 LYS n 
1 749 ASP n 
1 750 GLY n 
1 751 LYS n 
1 752 ILE n 
1 753 ASP n 
1 754 PHE n 
1 755 THR n 
1 756 ILE n 
1 757 ASN n 
1 758 THR n 
1 759 ASN n 
1 760 GLY n 
1 761 GLY n 
1 762 LEU n 
1 763 ARG n 
1 764 ASN n 
1 765 ARG n 
1 766 VAL n 
1 767 TYR n 
1 768 GLU n 
1 769 VAL n 
1 770 PRO n 
1 771 VAL n 
1 772 GLU n 
1 773 THR n 
1 774 LYS n 
1 775 PHE n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   775 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 SLC26A3 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            HEk293 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                             ?         'C3 H7 N O2'        89.093 
ARG 'L-peptide linking' y ARGININE                                                            ?         'C6 H15 N4 O2 1'    
175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                          ?         'C4 H8 N2 O3'       
132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                     ?         'C4 H7 N O4'        
133.103 
CL  non-polymer         . 'CHLORIDE ION'                                                      ?         'Cl -1'             35.453 
CYS 'L-peptide linking' y CYSTEINE                                                            ?         'C3 H7 N O2 S'      
121.158 
GLN 'L-peptide linking' y GLUTAMINE                                                           ?         'C5 H10 N2 O3'      
146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                     ?         'C5 H9 N O4'        
147.129 
GLY 'peptide linking'   y GLYCINE                                                             ?         'C2 H5 N O2'        75.067 
HIS 'L-peptide linking' y HISTIDINE                                                           ?         'C6 H10 N3 O2 1'    
156.162 
I2U non-polymer         . 5-chloranyl-2-oxidanyl-3-thiophen-2-ylcarbonyl-indole-1-carboxamide tenidap   'C14 H9 Cl N2 O3 S' 
320.751 
ILE 'L-peptide linking' y ISOLEUCINE                                                          ?         'C6 H13 N O2'       
131.173 
LEU 'L-peptide linking' y LEUCINE                                                             ?         'C6 H13 N O2'       
131.173 
LPE non-polymer         . 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE                           LPC-ETHER 'C26 H57 N O6 P 1'  
510.708 
LYS 'L-peptide linking' y LYSINE                                                              ?         'C6 H15 N2 O2 1'    
147.195 
MET 'L-peptide linking' y METHIONINE                                                          ?         'C5 H11 N O2 S'     
149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                                       ?         'C9 H11 N O2'       
165.189 
PRO 'L-peptide linking' y PROLINE                                                             ?         'C5 H9 N O2'        
115.130 
SER 'L-peptide linking' y SERINE                                                              ?         'C3 H7 N O3'        
105.093 
THR 'L-peptide linking' y THREONINE                                                           ?         'C4 H9 N O3'        
119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                          ?         'C11 H12 N2 O2'     
204.225 
TYR 'L-peptide linking' y TYROSINE                                                            ?         'C9 H11 N O3'       
181.189 
VAL 'L-peptide linking' y VALINE                                                              ?         'C5 H11 N O2'       
117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -10 ?   ?   ?   A . n 
A 1 2   ASP 2   -9  ?   ?   ?   A . n 
A 1 3   TYR 3   -8  ?   ?   ?   A . n 
A 1 4   LYS 4   -7  ?   ?   ?   A . n 
A 1 5   ASP 5   -6  ?   ?   ?   A . n 
A 1 6   ASP 6   -5  ?   ?   ?   A . n 
A 1 7   ASP 7   -4  ?   ?   ?   A . n 
A 1 8   ASP 8   -3  ?   ?   ?   A . n 
A 1 9   LYS 9   -2  ?   ?   ?   A . n 
A 1 10  GLY 10  -1  ?   ?   ?   A . n 
A 1 11  THR 11  0   ?   ?   ?   A . n 
A 1 12  MET 12  1   ?   ?   ?   A . n 
A 1 13  ILE 13  2   ?   ?   ?   A . n 
A 1 14  GLU 14  3   ?   ?   ?   A . n 
A 1 15  PRO 15  4   ?   ?   ?   A . n 
A 1 16  PHE 16  5   ?   ?   ?   A . n 
A 1 17  GLY 17  6   ?   ?   ?   A . n 
A 1 18  ASN 18  7   7   ASN ASN A . n 
A 1 19  GLN 19  8   8   GLN GLN A . n 
A 1 20  TYR 20  9   9   TYR TYR A . n 
A 1 21  ILE 21  10  10  ILE ILE A . n 
A 1 22  VAL 22  11  11  VAL VAL A . n 
A 1 23  ALA 23  12  12  ALA ALA A . n 
A 1 24  ARG 24  13  13  ARG ARG A . n 
A 1 25  PRO 25  14  14  PRO PRO A . n 
A 1 26  VAL 26  15  15  VAL VAL A . n 
A 1 27  TYR 27  16  16  TYR TYR A . n 
A 1 28  SER 28  17  17  SER SER A . n 
A 1 29  THR 29  18  18  THR THR A . n 
A 1 30  ASN 30  19  19  ASN ASN A . n 
A 1 31  ALA 31  20  20  ALA ALA A . n 
A 1 32  PHE 32  21  21  PHE PHE A . n 
A 1 33  GLU 33  22  22  GLU GLU A . n 
A 1 34  GLU 34  23  23  GLU GLU A . n 
A 1 35  ASN 35  24  24  ASN ASN A . n 
A 1 36  HIS 36  25  25  HIS HIS A . n 
A 1 37  LYS 37  26  26  LYS LYS A . n 
A 1 38  LYS 38  27  27  LYS LYS A . n 
A 1 39  THR 39  28  28  THR THR A . n 
A 1 40  GLY 40  29  29  GLY GLY A . n 
A 1 41  ARG 41  30  30  ARG ARG A . n 
A 1 42  HIS 42  31  31  HIS HIS A . n 
A 1 43  HIS 43  32  32  HIS HIS A . n 
A 1 44  LYS 44  33  33  LYS LYS A . n 
A 1 45  THR 45  34  34  THR THR A . n 
A 1 46  PHE 46  35  35  PHE PHE A . n 
A 1 47  LEU 47  36  36  LEU LEU A . n 
A 1 48  ASP 48  37  37  ASP ASP A . n 
A 1 49  HIS 49  38  38  HIS HIS A . n 
A 1 50  LEU 50  39  39  LEU LEU A . n 
A 1 51  LYS 51  40  40  LYS LYS A . n 
A 1 52  VAL 52  41  41  VAL VAL A . n 
A 1 53  CYS 53  42  42  CYS CYS A . n 
A 1 54  CYS 54  43  43  CYS CYS A . n 
A 1 55  SER 55  44  44  SER SER A . n 
A 1 56  CYS 56  45  45  CYS CYS A . n 
A 1 57  SER 57  46  46  SER SER A . n 
A 1 58  PRO 58  47  47  PRO PRO A . n 
A 1 59  GLN 59  48  48  GLN GLN A . n 
A 1 60  LYS 60  49  49  LYS LYS A . n 
A 1 61  ALA 61  50  50  ALA ALA A . n 
A 1 62  LYS 62  51  51  LYS LYS A . n 
A 1 63  ARG 63  52  52  ARG ARG A . n 
A 1 64  ILE 64  53  53  ILE ILE A . n 
A 1 65  VAL 65  54  54  VAL VAL A . n 
A 1 66  LEU 66  55  55  LEU LEU A . n 
A 1 67  SER 67  56  56  SER SER A . n 
A 1 68  LEU 68  57  57  LEU LEU A . n 
A 1 69  PHE 69  58  58  PHE PHE A . n 
A 1 70  PRO 70  59  59  PRO PRO A . n 
A 1 71  ILE 71  60  60  ILE ILE A . n 
A 1 72  ALA 72  61  61  ALA ALA A . n 
A 1 73  SER 73  62  62  SER SER A . n 
A 1 74  TRP 74  63  63  TRP TRP A . n 
A 1 75  LEU 75  64  64  LEU LEU A . n 
A 1 76  PRO 76  65  65  PRO PRO A . n 
A 1 77  ALA 77  66  66  ALA ALA A . n 
A 1 78  TYR 78  67  67  TYR TYR A . n 
A 1 79  ARG 79  68  68  ARG ARG A . n 
A 1 80  LEU 80  69  69  LEU LEU A . n 
A 1 81  LYS 81  70  70  LYS LYS A . n 
A 1 82  GLU 82  71  71  GLU GLU A . n 
A 1 83  TRP 83  72  72  TRP TRP A . n 
A 1 84  LEU 84  73  73  LEU LEU A . n 
A 1 85  LEU 85  74  74  LEU LEU A . n 
A 1 86  SER 86  75  75  SER SER A . n 
A 1 87  ASP 87  76  76  ASP ASP A . n 
A 1 88  ILE 88  77  77  ILE ILE A . n 
A 1 89  VAL 89  78  78  VAL VAL A . n 
A 1 90  SER 90  79  79  SER SER A . n 
A 1 91  GLY 91  80  80  GLY GLY A . n 
A 1 92  ILE 92  81  81  ILE ILE A . n 
A 1 93  SER 93  82  82  SER SER A . n 
A 1 94  THR 94  83  83  THR THR A . n 
A 1 95  GLY 95  84  84  GLY GLY A . n 
A 1 96  ILE 96  85  85  ILE ILE A . n 
A 1 97  VAL 97  86  86  VAL VAL A . n 
A 1 98  ALA 98  87  87  ALA ALA A . n 
A 1 99  VAL 99  88  88  VAL VAL A . n 
A 1 100 LEU 100 89  89  LEU LEU A . n 
A 1 101 GLN 101 90  90  GLN GLN A . n 
A 1 102 GLY 102 91  91  GLY GLY A . n 
A 1 103 LEU 103 92  92  LEU LEU A . n 
A 1 104 ALA 104 93  93  ALA ALA A . n 
A 1 105 PHE 105 94  94  PHE PHE A . n 
A 1 106 ALA 106 95  95  ALA ALA A . n 
A 1 107 LEU 107 96  96  LEU LEU A . n 
A 1 108 LEU 108 97  97  LEU LEU A . n 
A 1 109 VAL 109 98  98  VAL VAL A . n 
A 1 110 ASP 110 99  99  ASP ASP A . n 
A 1 111 ILE 111 100 100 ILE ILE A . n 
A 1 112 PRO 112 101 101 PRO PRO A . n 
A 1 113 PRO 113 102 102 PRO PRO A . n 
A 1 114 VAL 114 103 103 VAL VAL A . n 
A 1 115 TYR 115 104 104 TYR TYR A . n 
A 1 116 GLY 116 105 105 GLY GLY A . n 
A 1 117 LEU 117 106 106 LEU LEU A . n 
A 1 118 TYR 118 107 107 TYR TYR A . n 
A 1 119 ALA 119 108 108 ALA ALA A . n 
A 1 120 SER 120 109 109 SER SER A . n 
A 1 121 PHE 121 110 110 PHE PHE A . n 
A 1 122 PHE 122 111 111 PHE PHE A . n 
A 1 123 PRO 123 112 112 PRO PRO A . n 
A 1 124 ALA 124 113 113 ALA ALA A . n 
A 1 125 ILE 125 114 114 ILE ILE A . n 
A 1 126 ILE 126 115 115 ILE ILE A . n 
A 1 127 TYR 127 116 116 TYR TYR A . n 
A 1 128 LEU 128 117 117 LEU LEU A . n 
A 1 129 PHE 129 118 118 PHE PHE A . n 
A 1 130 PHE 130 119 119 PHE PHE A . n 
A 1 131 GLY 131 120 120 GLY GLY A . n 
A 1 132 THR 132 121 121 THR THR A . n 
A 1 133 SER 133 122 122 SER SER A . n 
A 1 134 ARG 134 123 123 ARG ARG A . n 
A 1 135 HIS 135 124 124 HIS HIS A . n 
A 1 136 ILE 136 125 125 ILE ILE A . n 
A 1 137 SER 137 126 126 SER SER A . n 
A 1 138 VAL 138 127 127 VAL VAL A . n 
A 1 139 GLY 139 128 128 GLY GLY A . n 
A 1 140 PRO 140 129 129 PRO PRO A . n 
A 1 141 PHE 141 130 130 PHE PHE A . n 
A 1 142 PRO 142 131 131 PRO PRO A . n 
A 1 143 ILE 143 132 132 ILE ILE A . n 
A 1 144 LEU 144 133 133 LEU LEU A . n 
A 1 145 SER 145 134 134 SER SER A . n 
A 1 146 MET 146 135 135 MET MET A . n 
A 1 147 MET 147 136 136 MET MET A . n 
A 1 148 VAL 148 137 137 VAL VAL A . n 
A 1 149 GLY 149 138 138 GLY GLY A . n 
A 1 150 LEU 150 139 139 LEU LEU A . n 
A 1 151 ALA 151 140 140 ALA ALA A . n 
A 1 152 VAL 152 141 141 VAL VAL A . n 
A 1 153 SER 153 142 142 SER SER A . n 
A 1 154 GLY 154 143 143 GLY GLY A . n 
A 1 155 ALA 155 144 144 ALA ALA A . n 
A 1 156 VAL 156 145 145 VAL VAL A . n 
A 1 157 SER 157 146 146 SER SER A . n 
A 1 158 LYS 158 147 147 LYS LYS A . n 
A 1 159 ALA 159 148 148 ALA ALA A . n 
A 1 160 VAL 160 149 149 VAL VAL A . n 
A 1 161 PRO 161 150 150 PRO PRO A . n 
A 1 162 ASP 162 151 ?   ?   ?   A . n 
A 1 163 ARG 163 152 ?   ?   ?   A . n 
A 1 164 ASN 164 153 ?   ?   ?   A . n 
A 1 165 ALA 165 154 ?   ?   ?   A . n 
A 1 166 THR 166 155 ?   ?   ?   A . n 
A 1 167 THR 167 156 ?   ?   ?   A . n 
A 1 168 LEU 168 157 ?   ?   ?   A . n 
A 1 169 GLY 169 158 ?   ?   ?   A . n 
A 1 170 LEU 170 159 ?   ?   ?   A . n 
A 1 171 PRO 171 160 ?   ?   ?   A . n 
A 1 172 ASN 172 161 ?   ?   ?   A . n 
A 1 173 ASN 173 162 ?   ?   ?   A . n 
A 1 174 SER 174 163 ?   ?   ?   A . n 
A 1 175 ASN 175 164 ?   ?   ?   A . n 
A 1 176 ASN 176 165 ?   ?   ?   A . n 
A 1 177 SER 177 166 ?   ?   ?   A . n 
A 1 178 SER 178 167 ?   ?   ?   A . n 
A 1 179 LEU 179 168 168 LEU LEU A . n 
A 1 180 LEU 180 169 169 LEU LEU A . n 
A 1 181 ASP 181 170 170 ASP ASP A . n 
A 1 182 ASP 182 171 171 ASP ASP A . n 
A 1 183 GLU 183 172 172 GLU GLU A . n 
A 1 184 ARG 184 173 173 ARG ARG A . n 
A 1 185 VAL 185 174 174 VAL VAL A . n 
A 1 186 ARG 186 175 175 ARG ARG A . n 
A 1 187 VAL 187 176 176 VAL VAL A . n 
A 1 188 ALA 188 177 177 ALA ALA A . n 
A 1 189 ALA 189 178 178 ALA ALA A . n 
A 1 190 ALA 190 179 179 ALA ALA A . n 
A 1 191 ALA 191 180 180 ALA ALA A . n 
A 1 192 SER 192 181 181 SER SER A . n 
A 1 193 VAL 193 182 182 VAL VAL A . n 
A 1 194 THR 194 183 183 THR THR A . n 
A 1 195 VAL 195 184 184 VAL VAL A . n 
A 1 196 LEU 196 185 185 LEU LEU A . n 
A 1 197 SER 197 186 186 SER SER A . n 
A 1 198 GLY 198 187 187 GLY GLY A . n 
A 1 199 ILE 199 188 188 ILE ILE A . n 
A 1 200 ILE 200 189 189 ILE ILE A . n 
A 1 201 GLN 201 190 190 GLN GLN A . n 
A 1 202 LEU 202 191 191 LEU LEU A . n 
A 1 203 ALA 203 192 192 ALA ALA A . n 
A 1 204 PHE 204 193 193 PHE PHE A . n 
A 1 205 GLY 205 194 194 GLY GLY A . n 
A 1 206 ILE 206 195 195 ILE ILE A . n 
A 1 207 LEU 207 196 196 LEU LEU A . n 
A 1 208 ARG 208 197 197 ARG ARG A . n 
A 1 209 ILE 209 198 198 ILE ILE A . n 
A 1 210 GLY 210 199 199 GLY GLY A . n 
A 1 211 PHE 211 200 200 PHE PHE A . n 
A 1 212 VAL 212 201 201 VAL VAL A . n 
A 1 213 VAL 213 202 202 VAL VAL A . n 
A 1 214 ILE 214 203 203 ILE ILE A . n 
A 1 215 TYR 215 204 204 TYR TYR A . n 
A 1 216 LEU 216 205 205 LEU LEU A . n 
A 1 217 SER 217 206 206 SER SER A . n 
A 1 218 GLU 218 207 207 GLU GLU A . n 
A 1 219 SER 219 208 208 SER SER A . n 
A 1 220 LEU 220 209 209 LEU LEU A . n 
A 1 221 ILE 221 210 210 ILE ILE A . n 
A 1 222 SER 222 211 211 SER SER A . n 
A 1 223 GLY 223 212 212 GLY GLY A . n 
A 1 224 PHE 224 213 213 PHE PHE A . n 
A 1 225 THR 225 214 214 THR THR A . n 
A 1 226 THR 226 215 215 THR THR A . n 
A 1 227 ALA 227 216 216 ALA ALA A . n 
A 1 228 ALA 228 217 217 ALA ALA A . n 
A 1 229 ALA 229 218 218 ALA ALA A . n 
A 1 230 VAL 230 219 219 VAL VAL A . n 
A 1 231 HIS 231 220 220 HIS HIS A . n 
A 1 232 VAL 232 221 221 VAL VAL A . n 
A 1 233 LEU 233 222 222 LEU LEU A . n 
A 1 234 VAL 234 223 223 VAL VAL A . n 
A 1 235 SER 235 224 224 SER SER A . n 
A 1 236 GLN 236 225 225 GLN GLN A . n 
A 1 237 LEU 237 226 226 LEU LEU A . n 
A 1 238 LYS 238 227 227 LYS LYS A . n 
A 1 239 PHE 239 228 228 PHE PHE A . n 
A 1 240 ILE 240 229 229 ILE ILE A . n 
A 1 241 PHE 241 230 230 PHE PHE A . n 
A 1 242 GLN 242 231 231 GLN GLN A . n 
A 1 243 LEU 243 232 232 LEU LEU A . n 
A 1 244 THR 244 233 233 THR THR A . n 
A 1 245 VAL 245 234 234 VAL VAL A . n 
A 1 246 PRO 246 235 235 PRO PRO A . n 
A 1 247 SER 247 236 236 SER SER A . n 
A 1 248 HIS 248 237 237 HIS HIS A . n 
A 1 249 THR 249 238 238 THR THR A . n 
A 1 250 ASP 250 239 239 ASP ASP A . n 
A 1 251 PRO 251 240 240 PRO PRO A . n 
A 1 252 VAL 252 241 241 VAL VAL A . n 
A 1 253 SER 253 242 242 SER SER A . n 
A 1 254 ILE 254 243 243 ILE ILE A . n 
A 1 255 PHE 255 244 244 PHE PHE A . n 
A 1 256 LYS 256 245 245 LYS LYS A . n 
A 1 257 VAL 257 246 246 VAL VAL A . n 
A 1 258 LEU 258 247 247 LEU LEU A . n 
A 1 259 TYR 259 248 248 TYR TYR A . n 
A 1 260 SER 260 249 249 SER SER A . n 
A 1 261 VAL 261 250 250 VAL VAL A . n 
A 1 262 PHE 262 251 251 PHE PHE A . n 
A 1 263 SER 263 252 252 SER SER A . n 
A 1 264 GLN 264 253 253 GLN GLN A . n 
A 1 265 ILE 265 254 254 ILE ILE A . n 
A 1 266 GLU 266 255 255 GLU GLU A . n 
A 1 267 LYS 267 256 256 LYS LYS A . n 
A 1 268 THR 268 257 257 THR THR A . n 
A 1 269 ASN 269 258 258 ASN ASN A . n 
A 1 270 ILE 270 259 259 ILE ILE A . n 
A 1 271 ALA 271 260 260 ALA ALA A . n 
A 1 272 ASP 272 261 261 ASP ASP A . n 
A 1 273 LEU 273 262 262 LEU LEU A . n 
A 1 274 VAL 274 263 263 VAL VAL A . n 
A 1 275 THR 275 264 264 THR THR A . n 
A 1 276 ALA 276 265 265 ALA ALA A . n 
A 1 277 LEU 277 266 266 LEU LEU A . n 
A 1 278 ILE 278 267 267 ILE ILE A . n 
A 1 279 VAL 279 268 268 VAL VAL A . n 
A 1 280 LEU 280 269 269 LEU LEU A . n 
A 1 281 LEU 281 270 270 LEU LEU A . n 
A 1 282 VAL 282 271 271 VAL VAL A . n 
A 1 283 VAL 283 272 272 VAL VAL A . n 
A 1 284 SER 284 273 273 SER SER A . n 
A 1 285 ILE 285 274 274 ILE ILE A . n 
A 1 286 VAL 286 275 275 VAL VAL A . n 
A 1 287 LYS 287 276 276 LYS LYS A . n 
A 1 288 GLU 288 277 277 GLU GLU A . n 
A 1 289 ILE 289 278 278 ILE ILE A . n 
A 1 290 ASN 290 279 279 ASN ASN A . n 
A 1 291 GLN 291 280 280 GLN GLN A . n 
A 1 292 ARG 292 281 281 ARG ARG A . n 
A 1 293 PHE 293 282 282 PHE PHE A . n 
A 1 294 LYS 294 283 283 LYS LYS A . n 
A 1 295 ASP 295 284 284 ASP ASP A . n 
A 1 296 LYS 296 285 285 LYS LYS A . n 
A 1 297 LEU 297 286 286 LEU LEU A . n 
A 1 298 PRO 298 287 287 PRO PRO A . n 
A 1 299 VAL 299 288 288 VAL VAL A . n 
A 1 300 PRO 300 289 289 PRO PRO A . n 
A 1 301 ILE 301 290 290 ILE ILE A . n 
A 1 302 PRO 302 291 291 PRO PRO A . n 
A 1 303 ILE 303 292 292 ILE ILE A . n 
A 1 304 GLU 304 293 293 GLU GLU A . n 
A 1 305 PHE 305 294 294 PHE PHE A . n 
A 1 306 ILE 306 295 295 ILE ILE A . n 
A 1 307 MET 307 296 296 MET MET A . n 
A 1 308 THR 308 297 297 THR THR A . n 
A 1 309 VAL 309 298 298 VAL VAL A . n 
A 1 310 ILE 310 299 299 ILE ILE A . n 
A 1 311 ALA 311 300 300 ALA ALA A . n 
A 1 312 ALA 312 301 301 ALA ALA A . n 
A 1 313 GLY 313 302 302 GLY GLY A . n 
A 1 314 VAL 314 303 303 VAL VAL A . n 
A 1 315 SER 315 304 304 SER SER A . n 
A 1 316 TYR 316 305 305 TYR TYR A . n 
A 1 317 GLY 317 306 306 GLY GLY A . n 
A 1 318 CYS 318 307 307 CYS CYS A . n 
A 1 319 ASP 319 308 308 ASP ASP A . n 
A 1 320 PHE 320 309 309 PHE PHE A . n 
A 1 321 LYS 321 310 310 LYS LYS A . n 
A 1 322 ASN 322 311 311 ASN ASN A . n 
A 1 323 ARG 323 312 312 ARG ARG A . n 
A 1 324 PHE 324 313 313 PHE PHE A . n 
A 1 325 LYS 325 314 314 LYS LYS A . n 
A 1 326 VAL 326 315 315 VAL VAL A . n 
A 1 327 ALA 327 316 316 ALA ALA A . n 
A 1 328 VAL 328 317 317 VAL VAL A . n 
A 1 329 VAL 329 318 318 VAL VAL A . n 
A 1 330 GLY 330 319 319 GLY GLY A . n 
A 1 331 ASP 331 320 320 ASP ASP A . n 
A 1 332 MET 332 321 321 MET MET A . n 
A 1 333 ASN 333 322 322 ASN ASN A . n 
A 1 334 PRO 334 323 323 PRO PRO A . n 
A 1 335 GLY 335 324 324 GLY GLY A . n 
A 1 336 PHE 336 325 325 PHE PHE A . n 
A 1 337 GLN 337 326 326 GLN GLN A . n 
A 1 338 PRO 338 327 327 PRO PRO A . n 
A 1 339 PRO 339 328 328 PRO PRO A . n 
A 1 340 ILE 340 329 329 ILE ILE A . n 
A 1 341 THR 341 330 330 THR THR A . n 
A 1 342 PRO 342 331 331 PRO PRO A . n 
A 1 343 ASP 343 332 332 ASP ASP A . n 
A 1 344 VAL 344 333 333 VAL VAL A . n 
A 1 345 GLU 345 334 334 GLU GLU A . n 
A 1 346 THR 346 335 335 THR THR A . n 
A 1 347 PHE 347 336 336 PHE PHE A . n 
A 1 348 GLN 348 337 337 GLN GLN A . n 
A 1 349 ASN 349 338 338 ASN ASN A . n 
A 1 350 THR 350 339 339 THR THR A . n 
A 1 351 VAL 351 340 340 VAL VAL A . n 
A 1 352 GLY 352 341 341 GLY GLY A . n 
A 1 353 ASP 353 342 342 ASP ASP A . n 
A 1 354 CYS 354 343 343 CYS CYS A . n 
A 1 355 PHE 355 344 344 PHE PHE A . n 
A 1 356 GLY 356 345 345 GLY GLY A . n 
A 1 357 ILE 357 346 346 ILE ILE A . n 
A 1 358 ALA 358 347 347 ALA ALA A . n 
A 1 359 MET 359 348 348 MET MET A . n 
A 1 360 VAL 360 349 349 VAL VAL A . n 
A 1 361 ALA 361 350 350 ALA ALA A . n 
A 1 362 PHE 362 351 351 PHE PHE A . n 
A 1 363 ALA 363 352 352 ALA ALA A . n 
A 1 364 VAL 364 353 353 VAL VAL A . n 
A 1 365 ALA 365 354 354 ALA ALA A . n 
A 1 366 PHE 366 355 355 PHE PHE A . n 
A 1 367 SER 367 356 356 SER SER A . n 
A 1 368 VAL 368 357 357 VAL VAL A . n 
A 1 369 ALA 369 358 358 ALA ALA A . n 
A 1 370 SER 370 359 359 SER SER A . n 
A 1 371 VAL 371 360 360 VAL VAL A . n 
A 1 372 TYR 372 361 361 TYR TYR A . n 
A 1 373 SER 373 362 362 SER SER A . n 
A 1 374 LEU 374 363 363 LEU LEU A . n 
A 1 375 LYS 375 364 364 LYS LYS A . n 
A 1 376 TYR 376 365 365 TYR TYR A . n 
A 1 377 ASP 377 366 366 ASP ASP A . n 
A 1 378 TYR 378 367 367 TYR TYR A . n 
A 1 379 PRO 379 368 368 PRO PRO A . n 
A 1 380 LEU 380 369 369 LEU LEU A . n 
A 1 381 ASP 381 370 370 ASP ASP A . n 
A 1 382 GLY 382 371 371 GLY GLY A . n 
A 1 383 ASN 383 372 372 ASN ASN A . n 
A 1 384 GLN 384 373 373 GLN GLN A . n 
A 1 385 GLU 385 374 374 GLU GLU A . n 
A 1 386 LEU 386 375 375 LEU LEU A . n 
A 1 387 ILE 387 376 376 ILE ILE A . n 
A 1 388 ALA 388 377 377 ALA ALA A . n 
A 1 389 LEU 389 378 378 LEU LEU A . n 
A 1 390 GLY 390 379 379 GLY GLY A . n 
A 1 391 LEU 391 380 380 LEU LEU A . n 
A 1 392 GLY 392 381 381 GLY GLY A . n 
A 1 393 ASN 393 382 382 ASN ASN A . n 
A 1 394 ILE 394 383 383 ILE ILE A . n 
A 1 395 VAL 395 384 384 VAL VAL A . n 
A 1 396 CYS 396 385 385 CYS CYS A . n 
A 1 397 GLY 397 386 386 GLY GLY A . n 
A 1 398 VAL 398 387 387 VAL VAL A . n 
A 1 399 PHE 399 388 388 PHE PHE A . n 
A 1 400 ARG 400 389 389 ARG ARG A . n 
A 1 401 GLY 401 390 390 GLY GLY A . n 
A 1 402 PHE 402 391 391 PHE PHE A . n 
A 1 403 ALA 403 392 392 ALA ALA A . n 
A 1 404 GLY 404 393 393 GLY GLY A . n 
A 1 405 SER 405 394 394 SER SER A . n 
A 1 406 THR 406 395 395 THR THR A . n 
A 1 407 ALA 407 396 396 ALA ALA A . n 
A 1 408 LEU 408 397 397 LEU LEU A . n 
A 1 409 SER 409 398 398 SER SER A . n 
A 1 410 ARG 410 399 399 ARG ARG A . n 
A 1 411 SER 411 400 400 SER SER A . n 
A 1 412 ALA 412 401 401 ALA ALA A . n 
A 1 413 VAL 413 402 402 VAL VAL A . n 
A 1 414 GLN 414 403 403 GLN GLN A . n 
A 1 415 GLU 415 404 404 GLU GLU A . n 
A 1 416 SER 416 405 405 SER SER A . n 
A 1 417 THR 417 406 406 THR THR A . n 
A 1 418 GLY 418 407 407 GLY GLY A . n 
A 1 419 GLY 419 408 408 GLY GLY A . n 
A 1 420 LYS 420 409 409 LYS LYS A . n 
A 1 421 THR 421 410 410 THR THR A . n 
A 1 422 GLN 422 411 411 GLN GLN A . n 
A 1 423 ILE 423 412 412 ILE ILE A . n 
A 1 424 ALA 424 413 413 ALA ALA A . n 
A 1 425 GLY 425 414 414 GLY GLY A . n 
A 1 426 LEU 426 415 415 LEU LEU A . n 
A 1 427 ILE 427 416 416 ILE ILE A . n 
A 1 428 GLY 428 417 417 GLY GLY A . n 
A 1 429 ALA 429 418 418 ALA ALA A . n 
A 1 430 ILE 430 419 419 ILE ILE A . n 
A 1 431 ILE 431 420 420 ILE ILE A . n 
A 1 432 VAL 432 421 421 VAL VAL A . n 
A 1 433 LEU 433 422 422 LEU LEU A . n 
A 1 434 ILE 434 423 423 ILE ILE A . n 
A 1 435 VAL 435 424 424 VAL VAL A . n 
A 1 436 VAL 436 425 425 VAL VAL A . n 
A 1 437 LEU 437 426 426 LEU LEU A . n 
A 1 438 ALA 438 427 427 ALA ALA A . n 
A 1 439 ILE 439 428 428 ILE ILE A . n 
A 1 440 GLY 440 429 429 GLY GLY A . n 
A 1 441 PHE 441 430 430 PHE PHE A . n 
A 1 442 LEU 442 431 431 LEU LEU A . n 
A 1 443 LEU 443 432 432 LEU LEU A . n 
A 1 444 ALA 444 433 433 ALA ALA A . n 
A 1 445 PRO 445 434 434 PRO PRO A . n 
A 1 446 LEU 446 435 435 LEU LEU A . n 
A 1 447 GLN 447 436 436 GLN GLN A . n 
A 1 448 LYS 448 437 437 LYS LYS A . n 
A 1 449 SER 449 438 438 SER SER A . n 
A 1 450 VAL 450 439 439 VAL VAL A . n 
A 1 451 LEU 451 440 440 LEU LEU A . n 
A 1 452 ALA 452 441 441 ALA ALA A . n 
A 1 453 ALA 453 442 442 ALA ALA A . n 
A 1 454 LEU 454 443 443 LEU LEU A . n 
A 1 455 ALA 455 444 444 ALA ALA A . n 
A 1 456 LEU 456 445 445 LEU LEU A . n 
A 1 457 GLY 457 446 446 GLY GLY A . n 
A 1 458 ASN 458 447 447 ASN ASN A . n 
A 1 459 LEU 459 448 448 LEU LEU A . n 
A 1 460 LYS 460 449 449 LYS LYS A . n 
A 1 461 GLY 461 450 450 GLY GLY A . n 
A 1 462 MET 462 451 451 MET MET A . n 
A 1 463 LEU 463 452 452 LEU LEU A . n 
A 1 464 MET 464 453 453 MET MET A . n 
A 1 465 GLN 465 454 454 GLN GLN A . n 
A 1 466 PHE 466 455 455 PHE PHE A . n 
A 1 467 ALA 467 456 456 ALA ALA A . n 
A 1 468 GLU 468 457 457 GLU GLU A . n 
A 1 469 ILE 469 458 458 ILE ILE A . n 
A 1 470 GLY 470 459 459 GLY GLY A . n 
A 1 471 ARG 471 460 460 ARG ARG A . n 
A 1 472 LEU 472 461 461 LEU LEU A . n 
A 1 473 TRP 473 462 462 TRP TRP A . n 
A 1 474 ARG 474 463 463 ARG ARG A . n 
A 1 475 LYS 475 464 464 LYS LYS A . n 
A 1 476 ASP 476 465 465 ASP ASP A . n 
A 1 477 LYS 477 466 466 LYS LYS A . n 
A 1 478 TYR 478 467 467 TYR TYR A . n 
A 1 479 ASP 479 468 468 ASP ASP A . n 
A 1 480 CYS 480 469 469 CYS CYS A . n 
A 1 481 LEU 481 470 470 LEU LEU A . n 
A 1 482 ILE 482 471 471 ILE ILE A . n 
A 1 483 TRP 483 472 472 TRP TRP A . n 
A 1 484 ILE 484 473 473 ILE ILE A . n 
A 1 485 MET 485 474 474 MET MET A . n 
A 1 486 THR 486 475 475 THR THR A . n 
A 1 487 PHE 487 476 476 PHE PHE A . n 
A 1 488 ILE 488 477 477 ILE ILE A . n 
A 1 489 PHE 489 478 478 PHE PHE A . n 
A 1 490 THR 490 479 479 THR THR A . n 
A 1 491 ILE 491 480 480 ILE ILE A . n 
A 1 492 VAL 492 481 481 VAL VAL A . n 
A 1 493 LEU 493 482 482 LEU LEU A . n 
A 1 494 GLY 494 483 483 GLY GLY A . n 
A 1 495 LEU 495 484 484 LEU LEU A . n 
A 1 496 GLY 496 485 485 GLY GLY A . n 
A 1 497 LEU 497 486 486 LEU LEU A . n 
A 1 498 GLY 498 487 487 GLY GLY A . n 
A 1 499 LEU 499 488 488 LEU LEU A . n 
A 1 500 ALA 500 489 489 ALA ALA A . n 
A 1 501 ALA 501 490 490 ALA ALA A . n 
A 1 502 SER 502 491 491 SER SER A . n 
A 1 503 VAL 503 492 492 VAL VAL A . n 
A 1 504 ALA 504 493 493 ALA ALA A . n 
A 1 505 PHE 505 494 494 PHE PHE A . n 
A 1 506 GLN 506 495 495 GLN GLN A . n 
A 1 507 LEU 507 496 496 LEU LEU A . n 
A 1 508 LEU 508 497 497 LEU LEU A . n 
A 1 509 THR 509 498 498 THR THR A . n 
A 1 510 ILE 510 499 499 ILE ILE A . n 
A 1 511 VAL 511 500 500 VAL VAL A . n 
A 1 512 PHE 512 501 501 PHE PHE A . n 
A 1 513 ARG 513 502 502 ARG ARG A . n 
A 1 514 THR 514 503 503 THR THR A . n 
A 1 515 GLN 515 504 504 GLN GLN A . n 
A 1 516 PHE 516 505 505 PHE PHE A . n 
A 1 517 PRO 517 506 506 PRO PRO A . n 
A 1 518 LYS 518 507 507 LYS LYS A . n 
A 1 519 CYS 519 508 508 CYS CYS A . n 
A 1 520 SER 520 509 509 SER SER A . n 
A 1 521 THR 521 510 510 THR THR A . n 
A 1 522 LEU 522 511 511 LEU LEU A . n 
A 1 523 ALA 523 512 512 ALA ALA A . n 
A 1 524 ASN 524 513 513 ASN ASN A . n 
A 1 525 ILE 525 514 514 ILE ILE A . n 
A 1 526 GLY 526 515 515 GLY GLY A . n 
A 1 527 ARG 527 516 516 ARG ARG A . n 
A 1 528 THR 528 517 517 THR THR A . n 
A 1 529 ASN 529 518 518 ASN ASN A . n 
A 1 530 ILE 530 519 519 ILE ILE A . n 
A 1 531 TYR 531 520 520 TYR TYR A . n 
A 1 532 LYS 532 521 521 LYS LYS A . n 
A 1 533 ASN 533 522 522 ASN ASN A . n 
A 1 534 LYS 534 523 523 LYS LYS A . n 
A 1 535 LYS 535 524 524 LYS LYS A . n 
A 1 536 ASP 536 525 525 ASP ASP A . n 
A 1 537 TYR 537 526 526 TYR TYR A . n 
A 1 538 TYR 538 527 527 TYR TYR A . n 
A 1 539 ASP 539 528 528 ASP ASP A . n 
A 1 540 MET 540 529 529 MET MET A . n 
A 1 541 TYR 541 530 530 TYR TYR A . n 
A 1 542 GLU 542 531 531 GLU GLU A . n 
A 1 543 PRO 543 532 532 PRO PRO A . n 
A 1 544 GLU 544 533 533 GLU GLU A . n 
A 1 545 GLY 545 534 534 GLY GLY A . n 
A 1 546 VAL 546 535 535 VAL VAL A . n 
A 1 547 LYS 547 536 536 LYS LYS A . n 
A 1 548 ILE 548 537 537 ILE ILE A . n 
A 1 549 PHE 549 538 538 PHE PHE A . n 
A 1 550 ARG 550 539 539 ARG ARG A . n 
A 1 551 CYS 551 540 540 CYS CYS A . n 
A 1 552 PRO 552 541 541 PRO PRO A . n 
A 1 553 SER 553 542 542 SER SER A . n 
A 1 554 PRO 554 543 543 PRO PRO A . n 
A 1 555 ILE 555 544 544 ILE ILE A . n 
A 1 556 TYR 556 545 545 TYR TYR A . n 
A 1 557 PHE 557 546 546 PHE PHE A . n 
A 1 558 ALA 558 547 547 ALA ALA A . n 
A 1 559 ASN 559 548 548 ASN ASN A . n 
A 1 560 ILE 560 549 549 ILE ILE A . n 
A 1 561 GLY 561 550 550 GLY GLY A . n 
A 1 562 PHE 562 551 551 PHE PHE A . n 
A 1 563 PHE 563 552 552 PHE PHE A . n 
A 1 564 ARG 564 553 553 ARG ARG A . n 
A 1 565 ARG 565 554 554 ARG ARG A . n 
A 1 566 LYS 566 555 555 LYS LYS A . n 
A 1 567 LEU 567 556 556 LEU LEU A . n 
A 1 568 ILE 568 557 557 ILE ILE A . n 
A 1 569 ASP 569 558 558 ASP ASP A . n 
A 1 570 ALA 570 559 559 ALA ALA A . n 
A 1 571 VAL 571 560 560 VAL VAL A . n 
A 1 572 GLY 572 561 561 GLY GLY A . n 
A 1 573 PHE 573 562 562 PHE PHE A . n 
A 1 574 SER 574 563 563 SER SER A . n 
A 1 575 PRO 575 564 564 PRO PRO A . n 
A 1 576 LEU 576 565 565 LEU LEU A . n 
A 1 577 ARG 577 566 566 ARG ARG A . n 
A 1 578 ILE 578 567 567 ILE ILE A . n 
A 1 579 LEU 579 568 568 LEU LEU A . n 
A 1 580 ARG 580 569 569 ARG ARG A . n 
A 1 581 LYS 581 570 570 LYS LYS A . n 
A 1 582 ARG 582 571 571 ARG ARG A . n 
A 1 583 ASN 583 572 572 ASN ASN A . n 
A 1 584 LYS 584 573 573 LYS LYS A . n 
A 1 585 ALA 585 574 574 ALA ALA A . n 
A 1 586 LEU 586 575 575 LEU LEU A . n 
A 1 587 ARG 587 576 576 ARG ARG A . n 
A 1 588 LYS 588 577 577 LYS LYS A . n 
A 1 589 ILE 589 578 578 ILE ILE A . n 
A 1 590 ARG 590 579 579 ARG ARG A . n 
A 1 591 LYS 591 580 580 LYS LYS A . n 
A 1 592 LEU 592 581 581 LEU LEU A . n 
A 1 593 GLN 593 582 582 GLN GLN A . n 
A 1 594 LYS 594 583 583 LYS LYS A . n 
A 1 595 GLN 595 584 584 GLN GLN A . n 
A 1 596 GLY 596 585 585 GLY GLY A . n 
A 1 597 LEU 597 586 586 LEU LEU A . n 
A 1 598 LEU 598 587 587 LEU LEU A . n 
A 1 599 GLN 599 588 588 GLN GLN A . n 
A 1 600 VAL 600 589 589 VAL VAL A . n 
A 1 601 THR 601 590 590 THR THR A . n 
A 1 602 PRO 602 591 591 PRO PRO A . n 
A 1 603 LYS 603 592 592 LYS LYS A . n 
A 1 604 GLY 604 593 593 GLY GLY A . n 
A 1 605 PHE 605 594 594 PHE PHE A . n 
A 1 606 ILE 606 595 595 ILE ILE A . n 
A 1 607 CYS 607 596 596 CYS CYS A . n 
A 1 608 THR 608 597 597 THR THR A . n 
A 1 609 VAL 609 598 598 VAL VAL A . n 
A 1 610 ASP 610 599 599 ASP ASP A . n 
A 1 611 THR 611 600 600 THR THR A . n 
A 1 612 ILE 612 601 601 ILE ILE A . n 
A 1 613 LYS 613 602 602 LYS LYS A . n 
A 1 614 ASP 614 603 603 ASP ASP A . n 
A 1 615 SER 615 604 604 SER SER A . n 
A 1 616 ASP 616 605 605 ASP ASP A . n 
A 1 617 GLU 617 606 606 GLU GLU A . n 
A 1 618 GLU 618 607 607 GLU GLU A . n 
A 1 619 LEU 619 608 608 LEU LEU A . n 
A 1 620 ASP 620 609 609 ASP ASP A . n 
A 1 621 ASN 621 610 610 ASN ASN A . n 
A 1 622 ASN 622 611 611 ASN ASN A . n 
A 1 623 GLN 623 612 612 GLN GLN A . n 
A 1 624 ILE 624 613 613 ILE ILE A . n 
A 1 625 GLU 625 614 614 GLU GLU A . n 
A 1 626 VAL 626 615 615 VAL VAL A . n 
A 1 627 LEU 627 616 616 LEU LEU A . n 
A 1 628 ASP 628 617 617 ASP ASP A . n 
A 1 629 GLN 629 618 618 GLN GLN A . n 
A 1 630 PRO 630 619 619 PRO PRO A . n 
A 1 631 ILE 631 620 620 ILE ILE A . n 
A 1 632 ASN 632 621 621 ASN ASN A . n 
A 1 633 THR 633 622 622 THR THR A . n 
A 1 634 THR 634 623 623 THR THR A . n 
A 1 635 ASP 635 624 624 ASP ASP A . n 
A 1 636 LEU 636 625 625 LEU LEU A . n 
A 1 637 PRO 637 626 626 PRO PRO A . n 
A 1 638 PHE 638 627 627 PHE PHE A . n 
A 1 639 HIS 639 628 628 HIS HIS A . n 
A 1 640 ILE 640 629 629 ILE ILE A . n 
A 1 641 ASP 641 630 630 ASP ASP A . n 
A 1 642 TRP 642 631 631 TRP TRP A . n 
A 1 643 ASN 643 632 632 ASN ASN A . n 
A 1 644 ASP 644 633 633 ASP ASP A . n 
A 1 645 ASP 645 634 634 ASP ASP A . n 
A 1 646 LEU 646 635 635 LEU LEU A . n 
A 1 647 PRO 647 636 636 PRO PRO A . n 
A 1 648 LEU 648 637 637 LEU LEU A . n 
A 1 649 ASN 649 638 638 ASN ASN A . n 
A 1 650 ILE 650 639 639 ILE ILE A . n 
A 1 651 GLU 651 640 640 GLU GLU A . n 
A 1 652 VAL 652 641 641 VAL VAL A . n 
A 1 653 PRO 653 642 642 PRO PRO A . n 
A 1 654 LYS 654 643 643 LYS LYS A . n 
A 1 655 ILE 655 644 644 ILE ILE A . n 
A 1 656 SER 656 645 645 SER SER A . n 
A 1 657 LEU 657 646 646 LEU LEU A . n 
A 1 658 HIS 658 647 647 HIS HIS A . n 
A 1 659 SER 659 648 648 SER SER A . n 
A 1 660 LEU 660 649 649 LEU LEU A . n 
A 1 661 ILE 661 650 650 ILE ILE A . n 
A 1 662 LEU 662 651 651 LEU LEU A . n 
A 1 663 ASP 663 652 652 ASP ASP A . n 
A 1 664 PHE 664 653 653 PHE PHE A . n 
A 1 665 SER 665 654 654 SER SER A . n 
A 1 666 ALA 666 655 655 ALA ALA A . n 
A 1 667 VAL 667 656 656 VAL VAL A . n 
A 1 668 SER 668 657 657 SER SER A . n 
A 1 669 PHE 669 658 658 PHE PHE A . n 
A 1 670 LEU 670 659 659 LEU LEU A . n 
A 1 671 ASP 671 660 660 ASP ASP A . n 
A 1 672 VAL 672 661 661 VAL VAL A . n 
A 1 673 SER 673 662 662 SER SER A . n 
A 1 674 SER 674 663 663 SER SER A . n 
A 1 675 VAL 675 664 664 VAL VAL A . n 
A 1 676 ARG 676 665 665 ARG ARG A . n 
A 1 677 GLY 677 666 666 GLY GLY A . n 
A 1 678 LEU 678 667 667 LEU LEU A . n 
A 1 679 LYS 679 668 668 LYS LYS A . n 
A 1 680 SER 680 669 669 SER SER A . n 
A 1 681 ILE 681 670 670 ILE ILE A . n 
A 1 682 LEU 682 671 671 LEU LEU A . n 
A 1 683 GLN 683 672 672 GLN GLN A . n 
A 1 684 GLU 684 673 673 GLU GLU A . n 
A 1 685 PHE 685 674 674 PHE PHE A . n 
A 1 686 ILE 686 675 675 ILE ILE A . n 
A 1 687 ARG 687 676 676 ARG ARG A . n 
A 1 688 ILE 688 677 677 ILE ILE A . n 
A 1 689 LYS 689 678 678 LYS LYS A . n 
A 1 690 VAL 690 679 679 VAL VAL A . n 
A 1 691 ASP 691 680 680 ASP ASP A . n 
A 1 692 VAL 692 681 681 VAL VAL A . n 
A 1 693 TYR 693 682 682 TYR TYR A . n 
A 1 694 ILE 694 683 683 ILE ILE A . n 
A 1 695 VAL 695 684 684 VAL VAL A . n 
A 1 696 GLY 696 685 685 GLY GLY A . n 
A 1 697 THR 697 686 686 THR THR A . n 
A 1 698 ASP 698 687 687 ASP ASP A . n 
A 1 699 ASP 699 688 688 ASP ASP A . n 
A 1 700 ASP 700 689 689 ASP ASP A . n 
A 1 701 PHE 701 690 690 PHE PHE A . n 
A 1 702 ILE 702 691 691 ILE ILE A . n 
A 1 703 GLU 703 692 692 GLU GLU A . n 
A 1 704 LYS 704 693 693 LYS LYS A . n 
A 1 705 LEU 705 694 694 LEU LEU A . n 
A 1 706 ASN 706 695 695 ASN ASN A . n 
A 1 707 ARG 707 696 696 ARG ARG A . n 
A 1 708 TYR 708 697 697 TYR TYR A . n 
A 1 709 GLU 709 698 698 GLU GLU A . n 
A 1 710 PHE 710 699 699 PHE PHE A . n 
A 1 711 PHE 711 700 700 PHE PHE A . n 
A 1 712 ASP 712 701 701 ASP ASP A . n 
A 1 713 GLY 713 702 702 GLY GLY A . n 
A 1 714 GLU 714 703 703 GLU GLU A . n 
A 1 715 VAL 715 704 704 VAL VAL A . n 
A 1 716 LYS 716 705 705 LYS LYS A . n 
A 1 717 SER 717 706 706 SER SER A . n 
A 1 718 SER 718 707 707 SER SER A . n 
A 1 719 ILE 719 708 708 ILE ILE A . n 
A 1 720 PHE 720 709 709 PHE PHE A . n 
A 1 721 PHE 721 710 710 PHE PHE A . n 
A 1 722 LEU 722 711 711 LEU LEU A . n 
A 1 723 THR 723 712 712 THR THR A . n 
A 1 724 ILE 724 713 713 ILE ILE A . n 
A 1 725 HIS 725 714 714 HIS HIS A . n 
A 1 726 ASP 726 715 715 ASP ASP A . n 
A 1 727 ALA 727 716 716 ALA ALA A . n 
A 1 728 VAL 728 717 717 VAL VAL A . n 
A 1 729 LEU 729 718 718 LEU LEU A . n 
A 1 730 HIS 730 719 719 HIS HIS A . n 
A 1 731 ILE 731 720 720 ILE ILE A . n 
A 1 732 LEU 732 721 721 LEU LEU A . n 
A 1 733 MET 733 722 722 MET MET A . n 
A 1 734 LYS 734 723 723 LYS LYS A . n 
A 1 735 LYS 735 724 724 LYS LYS A . n 
A 1 736 ASP 736 725 725 ASP ASP A . n 
A 1 737 TYR 737 726 ?   ?   ?   A . n 
A 1 738 SER 738 727 ?   ?   ?   A . n 
A 1 739 THR 739 728 ?   ?   ?   A . n 
A 1 740 SER 740 729 ?   ?   ?   A . n 
A 1 741 LYS 741 730 ?   ?   ?   A . n 
A 1 742 PHE 742 731 ?   ?   ?   A . n 
A 1 743 ASN 743 732 ?   ?   ?   A . n 
A 1 744 PRO 744 733 ?   ?   ?   A . n 
A 1 745 SER 745 734 ?   ?   ?   A . n 
A 1 746 GLN 746 735 ?   ?   ?   A . n 
A 1 747 GLU 747 736 ?   ?   ?   A . n 
A 1 748 LYS 748 737 ?   ?   ?   A . n 
A 1 749 ASP 749 738 ?   ?   ?   A . n 
A 1 750 GLY 750 739 ?   ?   ?   A . n 
A 1 751 LYS 751 740 ?   ?   ?   A . n 
A 1 752 ILE 752 741 ?   ?   ?   A . n 
A 1 753 ASP 753 742 ?   ?   ?   A . n 
A 1 754 PHE 754 743 ?   ?   ?   A . n 
A 1 755 THR 755 744 ?   ?   ?   A . n 
A 1 756 ILE 756 745 ?   ?   ?   A . n 
A 1 757 ASN 757 746 ?   ?   ?   A . n 
A 1 758 THR 758 747 ?   ?   ?   A . n 
A 1 759 ASN 759 748 ?   ?   ?   A . n 
A 1 760 GLY 760 749 ?   ?   ?   A . n 
A 1 761 GLY 761 750 ?   ?   ?   A . n 
A 1 762 LEU 762 751 ?   ?   ?   A . n 
A 1 763 ARG 763 752 ?   ?   ?   A . n 
A 1 764 ASN 764 753 ?   ?   ?   A . n 
A 1 765 ARG 765 754 ?   ?   ?   A . n 
A 1 766 VAL 766 755 ?   ?   ?   A . n 
A 1 767 TYR 767 756 ?   ?   ?   A . n 
A 1 768 GLU 768 757 ?   ?   ?   A . n 
A 1 769 VAL 769 758 ?   ?   ?   A . n 
A 1 770 PRO 770 759 ?   ?   ?   A . n 
A 1 771 VAL 771 760 ?   ?   ?   A . n 
A 1 772 GLU 772 761 ?   ?   ?   A . n 
A 1 773 THR 773 762 ?   ?   ?   A . n 
A 1 774 LYS 774 763 ?   ?   ?   A . n 
A 1 775 PHE 775 764 ?   ?   ?   A . n 
B 1 1   MET 1   -10 ?   ?   ?   B . n 
B 1 2   ASP 2   -9  ?   ?   ?   B . n 
B 1 3   TYR 3   -8  ?   ?   ?   B . n 
B 1 4   LYS 4   -7  ?   ?   ?   B . n 
B 1 5   ASP 5   -6  ?   ?   ?   B . n 
B 1 6   ASP 6   -5  ?   ?   ?   B . n 
B 1 7   ASP 7   -4  ?   ?   ?   B . n 
B 1 8   ASP 8   -3  ?   ?   ?   B . n 
B 1 9   LYS 9   -2  ?   ?   ?   B . n 
B 1 10  GLY 10  -1  ?   ?   ?   B . n 
B 1 11  THR 11  0   ?   ?   ?   B . n 
B 1 12  MET 12  1   ?   ?   ?   B . n 
B 1 13  ILE 13  2   ?   ?   ?   B . n 
B 1 14  GLU 14  3   ?   ?   ?   B . n 
B 1 15  PRO 15  4   ?   ?   ?   B . n 
B 1 16  PHE 16  5   ?   ?   ?   B . n 
B 1 17  GLY 17  6   ?   ?   ?   B . n 
B 1 18  ASN 18  7   7   ASN ASN B . n 
B 1 19  GLN 19  8   8   GLN GLN B . n 
B 1 20  TYR 20  9   9   TYR TYR B . n 
B 1 21  ILE 21  10  10  ILE ILE B . n 
B 1 22  VAL 22  11  11  VAL VAL B . n 
B 1 23  ALA 23  12  12  ALA ALA B . n 
B 1 24  ARG 24  13  13  ARG ARG B . n 
B 1 25  PRO 25  14  14  PRO PRO B . n 
B 1 26  VAL 26  15  15  VAL VAL B . n 
B 1 27  TYR 27  16  16  TYR TYR B . n 
B 1 28  SER 28  17  17  SER SER B . n 
B 1 29  THR 29  18  18  THR THR B . n 
B 1 30  ASN 30  19  19  ASN ASN B . n 
B 1 31  ALA 31  20  20  ALA ALA B . n 
B 1 32  PHE 32  21  21  PHE PHE B . n 
B 1 33  GLU 33  22  22  GLU GLU B . n 
B 1 34  GLU 34  23  23  GLU GLU B . n 
B 1 35  ASN 35  24  24  ASN ASN B . n 
B 1 36  HIS 36  25  25  HIS HIS B . n 
B 1 37  LYS 37  26  26  LYS LYS B . n 
B 1 38  LYS 38  27  27  LYS LYS B . n 
B 1 39  THR 39  28  28  THR THR B . n 
B 1 40  GLY 40  29  29  GLY GLY B . n 
B 1 41  ARG 41  30  30  ARG ARG B . n 
B 1 42  HIS 42  31  31  HIS HIS B . n 
B 1 43  HIS 43  32  32  HIS HIS B . n 
B 1 44  LYS 44  33  33  LYS LYS B . n 
B 1 45  THR 45  34  34  THR THR B . n 
B 1 46  PHE 46  35  35  PHE PHE B . n 
B 1 47  LEU 47  36  36  LEU LEU B . n 
B 1 48  ASP 48  37  37  ASP ASP B . n 
B 1 49  HIS 49  38  38  HIS HIS B . n 
B 1 50  LEU 50  39  39  LEU LEU B . n 
B 1 51  LYS 51  40  40  LYS LYS B . n 
B 1 52  VAL 52  41  41  VAL VAL B . n 
B 1 53  CYS 53  42  42  CYS CYS B . n 
B 1 54  CYS 54  43  43  CYS CYS B . n 
B 1 55  SER 55  44  44  SER SER B . n 
B 1 56  CYS 56  45  45  CYS CYS B . n 
B 1 57  SER 57  46  46  SER SER B . n 
B 1 58  PRO 58  47  47  PRO PRO B . n 
B 1 59  GLN 59  48  48  GLN GLN B . n 
B 1 60  LYS 60  49  49  LYS LYS B . n 
B 1 61  ALA 61  50  50  ALA ALA B . n 
B 1 62  LYS 62  51  51  LYS LYS B . n 
B 1 63  ARG 63  52  52  ARG ARG B . n 
B 1 64  ILE 64  53  53  ILE ILE B . n 
B 1 65  VAL 65  54  54  VAL VAL B . n 
B 1 66  LEU 66  55  55  LEU LEU B . n 
B 1 67  SER 67  56  56  SER SER B . n 
B 1 68  LEU 68  57  57  LEU LEU B . n 
B 1 69  PHE 69  58  58  PHE PHE B . n 
B 1 70  PRO 70  59  59  PRO PRO B . n 
B 1 71  ILE 71  60  60  ILE ILE B . n 
B 1 72  ALA 72  61  61  ALA ALA B . n 
B 1 73  SER 73  62  62  SER SER B . n 
B 1 74  TRP 74  63  63  TRP TRP B . n 
B 1 75  LEU 75  64  64  LEU LEU B . n 
B 1 76  PRO 76  65  65  PRO PRO B . n 
B 1 77  ALA 77  66  66  ALA ALA B . n 
B 1 78  TYR 78  67  67  TYR TYR B . n 
B 1 79  ARG 79  68  68  ARG ARG B . n 
B 1 80  LEU 80  69  69  LEU LEU B . n 
B 1 81  LYS 81  70  70  LYS LYS B . n 
B 1 82  GLU 82  71  71  GLU GLU B . n 
B 1 83  TRP 83  72  72  TRP TRP B . n 
B 1 84  LEU 84  73  73  LEU LEU B . n 
B 1 85  LEU 85  74  74  LEU LEU B . n 
B 1 86  SER 86  75  75  SER SER B . n 
B 1 87  ASP 87  76  76  ASP ASP B . n 
B 1 88  ILE 88  77  77  ILE ILE B . n 
B 1 89  VAL 89  78  78  VAL VAL B . n 
B 1 90  SER 90  79  79  SER SER B . n 
B 1 91  GLY 91  80  80  GLY GLY B . n 
B 1 92  ILE 92  81  81  ILE ILE B . n 
B 1 93  SER 93  82  82  SER SER B . n 
B 1 94  THR 94  83  83  THR THR B . n 
B 1 95  GLY 95  84  84  GLY GLY B . n 
B 1 96  ILE 96  85  85  ILE ILE B . n 
B 1 97  VAL 97  86  86  VAL VAL B . n 
B 1 98  ALA 98  87  87  ALA ALA B . n 
B 1 99  VAL 99  88  88  VAL VAL B . n 
B 1 100 LEU 100 89  89  LEU LEU B . n 
B 1 101 GLN 101 90  90  GLN GLN B . n 
B 1 102 GLY 102 91  91  GLY GLY B . n 
B 1 103 LEU 103 92  92  LEU LEU B . n 
B 1 104 ALA 104 93  93  ALA ALA B . n 
B 1 105 PHE 105 94  94  PHE PHE B . n 
B 1 106 ALA 106 95  95  ALA ALA B . n 
B 1 107 LEU 107 96  96  LEU LEU B . n 
B 1 108 LEU 108 97  97  LEU LEU B . n 
B 1 109 VAL 109 98  98  VAL VAL B . n 
B 1 110 ASP 110 99  99  ASP ASP B . n 
B 1 111 ILE 111 100 100 ILE ILE B . n 
B 1 112 PRO 112 101 101 PRO PRO B . n 
B 1 113 PRO 113 102 102 PRO PRO B . n 
B 1 114 VAL 114 103 103 VAL VAL B . n 
B 1 115 TYR 115 104 104 TYR TYR B . n 
B 1 116 GLY 116 105 105 GLY GLY B . n 
B 1 117 LEU 117 106 106 LEU LEU B . n 
B 1 118 TYR 118 107 107 TYR TYR B . n 
B 1 119 ALA 119 108 108 ALA ALA B . n 
B 1 120 SER 120 109 109 SER SER B . n 
B 1 121 PHE 121 110 110 PHE PHE B . n 
B 1 122 PHE 122 111 111 PHE PHE B . n 
B 1 123 PRO 123 112 112 PRO PRO B . n 
B 1 124 ALA 124 113 113 ALA ALA B . n 
B 1 125 ILE 125 114 114 ILE ILE B . n 
B 1 126 ILE 126 115 115 ILE ILE B . n 
B 1 127 TYR 127 116 116 TYR TYR B . n 
B 1 128 LEU 128 117 117 LEU LEU B . n 
B 1 129 PHE 129 118 118 PHE PHE B . n 
B 1 130 PHE 130 119 119 PHE PHE B . n 
B 1 131 GLY 131 120 120 GLY GLY B . n 
B 1 132 THR 132 121 121 THR THR B . n 
B 1 133 SER 133 122 122 SER SER B . n 
B 1 134 ARG 134 123 123 ARG ARG B . n 
B 1 135 HIS 135 124 124 HIS HIS B . n 
B 1 136 ILE 136 125 125 ILE ILE B . n 
B 1 137 SER 137 126 126 SER SER B . n 
B 1 138 VAL 138 127 127 VAL VAL B . n 
B 1 139 GLY 139 128 128 GLY GLY B . n 
B 1 140 PRO 140 129 129 PRO PRO B . n 
B 1 141 PHE 141 130 130 PHE PHE B . n 
B 1 142 PRO 142 131 131 PRO PRO B . n 
B 1 143 ILE 143 132 132 ILE ILE B . n 
B 1 144 LEU 144 133 133 LEU LEU B . n 
B 1 145 SER 145 134 134 SER SER B . n 
B 1 146 MET 146 135 135 MET MET B . n 
B 1 147 MET 147 136 136 MET MET B . n 
B 1 148 VAL 148 137 137 VAL VAL B . n 
B 1 149 GLY 149 138 138 GLY GLY B . n 
B 1 150 LEU 150 139 139 LEU LEU B . n 
B 1 151 ALA 151 140 140 ALA ALA B . n 
B 1 152 VAL 152 141 141 VAL VAL B . n 
B 1 153 SER 153 142 142 SER SER B . n 
B 1 154 GLY 154 143 143 GLY GLY B . n 
B 1 155 ALA 155 144 144 ALA ALA B . n 
B 1 156 VAL 156 145 145 VAL VAL B . n 
B 1 157 SER 157 146 146 SER SER B . n 
B 1 158 LYS 158 147 147 LYS LYS B . n 
B 1 159 ALA 159 148 148 ALA ALA B . n 
B 1 160 VAL 160 149 149 VAL VAL B . n 
B 1 161 PRO 161 150 150 PRO PRO B . n 
B 1 162 ASP 162 151 ?   ?   ?   B . n 
B 1 163 ARG 163 152 ?   ?   ?   B . n 
B 1 164 ASN 164 153 ?   ?   ?   B . n 
B 1 165 ALA 165 154 ?   ?   ?   B . n 
B 1 166 THR 166 155 ?   ?   ?   B . n 
B 1 167 THR 167 156 ?   ?   ?   B . n 
B 1 168 LEU 168 157 ?   ?   ?   B . n 
B 1 169 GLY 169 158 ?   ?   ?   B . n 
B 1 170 LEU 170 159 ?   ?   ?   B . n 
B 1 171 PRO 171 160 ?   ?   ?   B . n 
B 1 172 ASN 172 161 ?   ?   ?   B . n 
B 1 173 ASN 173 162 ?   ?   ?   B . n 
B 1 174 SER 174 163 ?   ?   ?   B . n 
B 1 175 ASN 175 164 ?   ?   ?   B . n 
B 1 176 ASN 176 165 ?   ?   ?   B . n 
B 1 177 SER 177 166 ?   ?   ?   B . n 
B 1 178 SER 178 167 ?   ?   ?   B . n 
B 1 179 LEU 179 168 168 LEU LEU B . n 
B 1 180 LEU 180 169 169 LEU LEU B . n 
B 1 181 ASP 181 170 170 ASP ASP B . n 
B 1 182 ASP 182 171 171 ASP ASP B . n 
B 1 183 GLU 183 172 172 GLU GLU B . n 
B 1 184 ARG 184 173 173 ARG ARG B . n 
B 1 185 VAL 185 174 174 VAL VAL B . n 
B 1 186 ARG 186 175 175 ARG ARG B . n 
B 1 187 VAL 187 176 176 VAL VAL B . n 
B 1 188 ALA 188 177 177 ALA ALA B . n 
B 1 189 ALA 189 178 178 ALA ALA B . n 
B 1 190 ALA 190 179 179 ALA ALA B . n 
B 1 191 ALA 191 180 180 ALA ALA B . n 
B 1 192 SER 192 181 181 SER SER B . n 
B 1 193 VAL 193 182 182 VAL VAL B . n 
B 1 194 THR 194 183 183 THR THR B . n 
B 1 195 VAL 195 184 184 VAL VAL B . n 
B 1 196 LEU 196 185 185 LEU LEU B . n 
B 1 197 SER 197 186 186 SER SER B . n 
B 1 198 GLY 198 187 187 GLY GLY B . n 
B 1 199 ILE 199 188 188 ILE ILE B . n 
B 1 200 ILE 200 189 189 ILE ILE B . n 
B 1 201 GLN 201 190 190 GLN GLN B . n 
B 1 202 LEU 202 191 191 LEU LEU B . n 
B 1 203 ALA 203 192 192 ALA ALA B . n 
B 1 204 PHE 204 193 193 PHE PHE B . n 
B 1 205 GLY 205 194 194 GLY GLY B . n 
B 1 206 ILE 206 195 195 ILE ILE B . n 
B 1 207 LEU 207 196 196 LEU LEU B . n 
B 1 208 ARG 208 197 197 ARG ARG B . n 
B 1 209 ILE 209 198 198 ILE ILE B . n 
B 1 210 GLY 210 199 199 GLY GLY B . n 
B 1 211 PHE 211 200 200 PHE PHE B . n 
B 1 212 VAL 212 201 201 VAL VAL B . n 
B 1 213 VAL 213 202 202 VAL VAL B . n 
B 1 214 ILE 214 203 203 ILE ILE B . n 
B 1 215 TYR 215 204 204 TYR TYR B . n 
B 1 216 LEU 216 205 205 LEU LEU B . n 
B 1 217 SER 217 206 206 SER SER B . n 
B 1 218 GLU 218 207 207 GLU GLU B . n 
B 1 219 SER 219 208 208 SER SER B . n 
B 1 220 LEU 220 209 209 LEU LEU B . n 
B 1 221 ILE 221 210 210 ILE ILE B . n 
B 1 222 SER 222 211 211 SER SER B . n 
B 1 223 GLY 223 212 212 GLY GLY B . n 
B 1 224 PHE 224 213 213 PHE PHE B . n 
B 1 225 THR 225 214 214 THR THR B . n 
B 1 226 THR 226 215 215 THR THR B . n 
B 1 227 ALA 227 216 216 ALA ALA B . n 
B 1 228 ALA 228 217 217 ALA ALA B . n 
B 1 229 ALA 229 218 218 ALA ALA B . n 
B 1 230 VAL 230 219 219 VAL VAL B . n 
B 1 231 HIS 231 220 220 HIS HIS B . n 
B 1 232 VAL 232 221 221 VAL VAL B . n 
B 1 233 LEU 233 222 222 LEU LEU B . n 
B 1 234 VAL 234 223 223 VAL VAL B . n 
B 1 235 SER 235 224 224 SER SER B . n 
B 1 236 GLN 236 225 225 GLN GLN B . n 
B 1 237 LEU 237 226 226 LEU LEU B . n 
B 1 238 LYS 238 227 227 LYS LYS B . n 
B 1 239 PHE 239 228 228 PHE PHE B . n 
B 1 240 ILE 240 229 229 ILE ILE B . n 
B 1 241 PHE 241 230 230 PHE PHE B . n 
B 1 242 GLN 242 231 231 GLN GLN B . n 
B 1 243 LEU 243 232 232 LEU LEU B . n 
B 1 244 THR 244 233 233 THR THR B . n 
B 1 245 VAL 245 234 234 VAL VAL B . n 
B 1 246 PRO 246 235 235 PRO PRO B . n 
B 1 247 SER 247 236 236 SER SER B . n 
B 1 248 HIS 248 237 237 HIS HIS B . n 
B 1 249 THR 249 238 238 THR THR B . n 
B 1 250 ASP 250 239 239 ASP ASP B . n 
B 1 251 PRO 251 240 240 PRO PRO B . n 
B 1 252 VAL 252 241 241 VAL VAL B . n 
B 1 253 SER 253 242 242 SER SER B . n 
B 1 254 ILE 254 243 243 ILE ILE B . n 
B 1 255 PHE 255 244 244 PHE PHE B . n 
B 1 256 LYS 256 245 245 LYS LYS B . n 
B 1 257 VAL 257 246 246 VAL VAL B . n 
B 1 258 LEU 258 247 247 LEU LEU B . n 
B 1 259 TYR 259 248 248 TYR TYR B . n 
B 1 260 SER 260 249 249 SER SER B . n 
B 1 261 VAL 261 250 250 VAL VAL B . n 
B 1 262 PHE 262 251 251 PHE PHE B . n 
B 1 263 SER 263 252 252 SER SER B . n 
B 1 264 GLN 264 253 253 GLN GLN B . n 
B 1 265 ILE 265 254 254 ILE ILE B . n 
B 1 266 GLU 266 255 255 GLU GLU B . n 
B 1 267 LYS 267 256 256 LYS LYS B . n 
B 1 268 THR 268 257 257 THR THR B . n 
B 1 269 ASN 269 258 258 ASN ASN B . n 
B 1 270 ILE 270 259 259 ILE ILE B . n 
B 1 271 ALA 271 260 260 ALA ALA B . n 
B 1 272 ASP 272 261 261 ASP ASP B . n 
B 1 273 LEU 273 262 262 LEU LEU B . n 
B 1 274 VAL 274 263 263 VAL VAL B . n 
B 1 275 THR 275 264 264 THR THR B . n 
B 1 276 ALA 276 265 265 ALA ALA B . n 
B 1 277 LEU 277 266 266 LEU LEU B . n 
B 1 278 ILE 278 267 267 ILE ILE B . n 
B 1 279 VAL 279 268 268 VAL VAL B . n 
B 1 280 LEU 280 269 269 LEU LEU B . n 
B 1 281 LEU 281 270 270 LEU LEU B . n 
B 1 282 VAL 282 271 271 VAL VAL B . n 
B 1 283 VAL 283 272 272 VAL VAL B . n 
B 1 284 SER 284 273 273 SER SER B . n 
B 1 285 ILE 285 274 274 ILE ILE B . n 
B 1 286 VAL 286 275 275 VAL VAL B . n 
B 1 287 LYS 287 276 276 LYS LYS B . n 
B 1 288 GLU 288 277 277 GLU GLU B . n 
B 1 289 ILE 289 278 278 ILE ILE B . n 
B 1 290 ASN 290 279 279 ASN ASN B . n 
B 1 291 GLN 291 280 280 GLN GLN B . n 
B 1 292 ARG 292 281 281 ARG ARG B . n 
B 1 293 PHE 293 282 282 PHE PHE B . n 
B 1 294 LYS 294 283 283 LYS LYS B . n 
B 1 295 ASP 295 284 284 ASP ASP B . n 
B 1 296 LYS 296 285 285 LYS LYS B . n 
B 1 297 LEU 297 286 286 LEU LEU B . n 
B 1 298 PRO 298 287 287 PRO PRO B . n 
B 1 299 VAL 299 288 288 VAL VAL B . n 
B 1 300 PRO 300 289 289 PRO PRO B . n 
B 1 301 ILE 301 290 290 ILE ILE B . n 
B 1 302 PRO 302 291 291 PRO PRO B . n 
B 1 303 ILE 303 292 292 ILE ILE B . n 
B 1 304 GLU 304 293 293 GLU GLU B . n 
B 1 305 PHE 305 294 294 PHE PHE B . n 
B 1 306 ILE 306 295 295 ILE ILE B . n 
B 1 307 MET 307 296 296 MET MET B . n 
B 1 308 THR 308 297 297 THR THR B . n 
B 1 309 VAL 309 298 298 VAL VAL B . n 
B 1 310 ILE 310 299 299 ILE ILE B . n 
B 1 311 ALA 311 300 300 ALA ALA B . n 
B 1 312 ALA 312 301 301 ALA ALA B . n 
B 1 313 GLY 313 302 302 GLY GLY B . n 
B 1 314 VAL 314 303 303 VAL VAL B . n 
B 1 315 SER 315 304 304 SER SER B . n 
B 1 316 TYR 316 305 305 TYR TYR B . n 
B 1 317 GLY 317 306 306 GLY GLY B . n 
B 1 318 CYS 318 307 307 CYS CYS B . n 
B 1 319 ASP 319 308 308 ASP ASP B . n 
B 1 320 PHE 320 309 309 PHE PHE B . n 
B 1 321 LYS 321 310 310 LYS LYS B . n 
B 1 322 ASN 322 311 311 ASN ASN B . n 
B 1 323 ARG 323 312 312 ARG ARG B . n 
B 1 324 PHE 324 313 313 PHE PHE B . n 
B 1 325 LYS 325 314 314 LYS LYS B . n 
B 1 326 VAL 326 315 315 VAL VAL B . n 
B 1 327 ALA 327 316 316 ALA ALA B . n 
B 1 328 VAL 328 317 317 VAL VAL B . n 
B 1 329 VAL 329 318 318 VAL VAL B . n 
B 1 330 GLY 330 319 319 GLY GLY B . n 
B 1 331 ASP 331 320 320 ASP ASP B . n 
B 1 332 MET 332 321 321 MET MET B . n 
B 1 333 ASN 333 322 322 ASN ASN B . n 
B 1 334 PRO 334 323 323 PRO PRO B . n 
B 1 335 GLY 335 324 324 GLY GLY B . n 
B 1 336 PHE 336 325 325 PHE PHE B . n 
B 1 337 GLN 337 326 326 GLN GLN B . n 
B 1 338 PRO 338 327 327 PRO PRO B . n 
B 1 339 PRO 339 328 328 PRO PRO B . n 
B 1 340 ILE 340 329 329 ILE ILE B . n 
B 1 341 THR 341 330 330 THR THR B . n 
B 1 342 PRO 342 331 331 PRO PRO B . n 
B 1 343 ASP 343 332 332 ASP ASP B . n 
B 1 344 VAL 344 333 333 VAL VAL B . n 
B 1 345 GLU 345 334 334 GLU GLU B . n 
B 1 346 THR 346 335 335 THR THR B . n 
B 1 347 PHE 347 336 336 PHE PHE B . n 
B 1 348 GLN 348 337 337 GLN GLN B . n 
B 1 349 ASN 349 338 338 ASN ASN B . n 
B 1 350 THR 350 339 339 THR THR B . n 
B 1 351 VAL 351 340 340 VAL VAL B . n 
B 1 352 GLY 352 341 341 GLY GLY B . n 
B 1 353 ASP 353 342 342 ASP ASP B . n 
B 1 354 CYS 354 343 343 CYS CYS B . n 
B 1 355 PHE 355 344 344 PHE PHE B . n 
B 1 356 GLY 356 345 345 GLY GLY B . n 
B 1 357 ILE 357 346 346 ILE ILE B . n 
B 1 358 ALA 358 347 347 ALA ALA B . n 
B 1 359 MET 359 348 348 MET MET B . n 
B 1 360 VAL 360 349 349 VAL VAL B . n 
B 1 361 ALA 361 350 350 ALA ALA B . n 
B 1 362 PHE 362 351 351 PHE PHE B . n 
B 1 363 ALA 363 352 352 ALA ALA B . n 
B 1 364 VAL 364 353 353 VAL VAL B . n 
B 1 365 ALA 365 354 354 ALA ALA B . n 
B 1 366 PHE 366 355 355 PHE PHE B . n 
B 1 367 SER 367 356 356 SER SER B . n 
B 1 368 VAL 368 357 357 VAL VAL B . n 
B 1 369 ALA 369 358 358 ALA ALA B . n 
B 1 370 SER 370 359 359 SER SER B . n 
B 1 371 VAL 371 360 360 VAL VAL B . n 
B 1 372 TYR 372 361 361 TYR TYR B . n 
B 1 373 SER 373 362 362 SER SER B . n 
B 1 374 LEU 374 363 363 LEU LEU B . n 
B 1 375 LYS 375 364 364 LYS LYS B . n 
B 1 376 TYR 376 365 365 TYR TYR B . n 
B 1 377 ASP 377 366 366 ASP ASP B . n 
B 1 378 TYR 378 367 367 TYR TYR B . n 
B 1 379 PRO 379 368 368 PRO PRO B . n 
B 1 380 LEU 380 369 369 LEU LEU B . n 
B 1 381 ASP 381 370 370 ASP ASP B . n 
B 1 382 GLY 382 371 371 GLY GLY B . n 
B 1 383 ASN 383 372 372 ASN ASN B . n 
B 1 384 GLN 384 373 373 GLN GLN B . n 
B 1 385 GLU 385 374 374 GLU GLU B . n 
B 1 386 LEU 386 375 375 LEU LEU B . n 
B 1 387 ILE 387 376 376 ILE ILE B . n 
B 1 388 ALA 388 377 377 ALA ALA B . n 
B 1 389 LEU 389 378 378 LEU LEU B . n 
B 1 390 GLY 390 379 379 GLY GLY B . n 
B 1 391 LEU 391 380 380 LEU LEU B . n 
B 1 392 GLY 392 381 381 GLY GLY B . n 
B 1 393 ASN 393 382 382 ASN ASN B . n 
B 1 394 ILE 394 383 383 ILE ILE B . n 
B 1 395 VAL 395 384 384 VAL VAL B . n 
B 1 396 CYS 396 385 385 CYS CYS B . n 
B 1 397 GLY 397 386 386 GLY GLY B . n 
B 1 398 VAL 398 387 387 VAL VAL B . n 
B 1 399 PHE 399 388 388 PHE PHE B . n 
B 1 400 ARG 400 389 389 ARG ARG B . n 
B 1 401 GLY 401 390 390 GLY GLY B . n 
B 1 402 PHE 402 391 391 PHE PHE B . n 
B 1 403 ALA 403 392 392 ALA ALA B . n 
B 1 404 GLY 404 393 393 GLY GLY B . n 
B 1 405 SER 405 394 394 SER SER B . n 
B 1 406 THR 406 395 395 THR THR B . n 
B 1 407 ALA 407 396 396 ALA ALA B . n 
B 1 408 LEU 408 397 397 LEU LEU B . n 
B 1 409 SER 409 398 398 SER SER B . n 
B 1 410 ARG 410 399 399 ARG ARG B . n 
B 1 411 SER 411 400 400 SER SER B . n 
B 1 412 ALA 412 401 401 ALA ALA B . n 
B 1 413 VAL 413 402 402 VAL VAL B . n 
B 1 414 GLN 414 403 403 GLN GLN B . n 
B 1 415 GLU 415 404 404 GLU GLU B . n 
B 1 416 SER 416 405 405 SER SER B . n 
B 1 417 THR 417 406 406 THR THR B . n 
B 1 418 GLY 418 407 407 GLY GLY B . n 
B 1 419 GLY 419 408 408 GLY GLY B . n 
B 1 420 LYS 420 409 409 LYS LYS B . n 
B 1 421 THR 421 410 410 THR THR B . n 
B 1 422 GLN 422 411 411 GLN GLN B . n 
B 1 423 ILE 423 412 412 ILE ILE B . n 
B 1 424 ALA 424 413 413 ALA ALA B . n 
B 1 425 GLY 425 414 414 GLY GLY B . n 
B 1 426 LEU 426 415 415 LEU LEU B . n 
B 1 427 ILE 427 416 416 ILE ILE B . n 
B 1 428 GLY 428 417 417 GLY GLY B . n 
B 1 429 ALA 429 418 418 ALA ALA B . n 
B 1 430 ILE 430 419 419 ILE ILE B . n 
B 1 431 ILE 431 420 420 ILE ILE B . n 
B 1 432 VAL 432 421 421 VAL VAL B . n 
B 1 433 LEU 433 422 422 LEU LEU B . n 
B 1 434 ILE 434 423 423 ILE ILE B . n 
B 1 435 VAL 435 424 424 VAL VAL B . n 
B 1 436 VAL 436 425 425 VAL VAL B . n 
B 1 437 LEU 437 426 426 LEU LEU B . n 
B 1 438 ALA 438 427 427 ALA ALA B . n 
B 1 439 ILE 439 428 428 ILE ILE B . n 
B 1 440 GLY 440 429 429 GLY GLY B . n 
B 1 441 PHE 441 430 430 PHE PHE B . n 
B 1 442 LEU 442 431 431 LEU LEU B . n 
B 1 443 LEU 443 432 432 LEU LEU B . n 
B 1 444 ALA 444 433 433 ALA ALA B . n 
B 1 445 PRO 445 434 434 PRO PRO B . n 
B 1 446 LEU 446 435 435 LEU LEU B . n 
B 1 447 GLN 447 436 436 GLN GLN B . n 
B 1 448 LYS 448 437 437 LYS LYS B . n 
B 1 449 SER 449 438 438 SER SER B . n 
B 1 450 VAL 450 439 439 VAL VAL B . n 
B 1 451 LEU 451 440 440 LEU LEU B . n 
B 1 452 ALA 452 441 441 ALA ALA B . n 
B 1 453 ALA 453 442 442 ALA ALA B . n 
B 1 454 LEU 454 443 443 LEU LEU B . n 
B 1 455 ALA 455 444 444 ALA ALA B . n 
B 1 456 LEU 456 445 445 LEU LEU B . n 
B 1 457 GLY 457 446 446 GLY GLY B . n 
B 1 458 ASN 458 447 447 ASN ASN B . n 
B 1 459 LEU 459 448 448 LEU LEU B . n 
B 1 460 LYS 460 449 449 LYS LYS B . n 
B 1 461 GLY 461 450 450 GLY GLY B . n 
B 1 462 MET 462 451 451 MET MET B . n 
B 1 463 LEU 463 452 452 LEU LEU B . n 
B 1 464 MET 464 453 453 MET MET B . n 
B 1 465 GLN 465 454 454 GLN GLN B . n 
B 1 466 PHE 466 455 455 PHE PHE B . n 
B 1 467 ALA 467 456 456 ALA ALA B . n 
B 1 468 GLU 468 457 457 GLU GLU B . n 
B 1 469 ILE 469 458 458 ILE ILE B . n 
B 1 470 GLY 470 459 459 GLY GLY B . n 
B 1 471 ARG 471 460 460 ARG ARG B . n 
B 1 472 LEU 472 461 461 LEU LEU B . n 
B 1 473 TRP 473 462 462 TRP TRP B . n 
B 1 474 ARG 474 463 463 ARG ARG B . n 
B 1 475 LYS 475 464 464 LYS LYS B . n 
B 1 476 ASP 476 465 465 ASP ASP B . n 
B 1 477 LYS 477 466 466 LYS LYS B . n 
B 1 478 TYR 478 467 467 TYR TYR B . n 
B 1 479 ASP 479 468 468 ASP ASP B . n 
B 1 480 CYS 480 469 469 CYS CYS B . n 
B 1 481 LEU 481 470 470 LEU LEU B . n 
B 1 482 ILE 482 471 471 ILE ILE B . n 
B 1 483 TRP 483 472 472 TRP TRP B . n 
B 1 484 ILE 484 473 473 ILE ILE B . n 
B 1 485 MET 485 474 474 MET MET B . n 
B 1 486 THR 486 475 475 THR THR B . n 
B 1 487 PHE 487 476 476 PHE PHE B . n 
B 1 488 ILE 488 477 477 ILE ILE B . n 
B 1 489 PHE 489 478 478 PHE PHE B . n 
B 1 490 THR 490 479 479 THR THR B . n 
B 1 491 ILE 491 480 480 ILE ILE B . n 
B 1 492 VAL 492 481 481 VAL VAL B . n 
B 1 493 LEU 493 482 482 LEU LEU B . n 
B 1 494 GLY 494 483 483 GLY GLY B . n 
B 1 495 LEU 495 484 484 LEU LEU B . n 
B 1 496 GLY 496 485 485 GLY GLY B . n 
B 1 497 LEU 497 486 486 LEU LEU B . n 
B 1 498 GLY 498 487 487 GLY GLY B . n 
B 1 499 LEU 499 488 488 LEU LEU B . n 
B 1 500 ALA 500 489 489 ALA ALA B . n 
B 1 501 ALA 501 490 490 ALA ALA B . n 
B 1 502 SER 502 491 491 SER SER B . n 
B 1 503 VAL 503 492 492 VAL VAL B . n 
B 1 504 ALA 504 493 493 ALA ALA B . n 
B 1 505 PHE 505 494 494 PHE PHE B . n 
B 1 506 GLN 506 495 495 GLN GLN B . n 
B 1 507 LEU 507 496 496 LEU LEU B . n 
B 1 508 LEU 508 497 497 LEU LEU B . n 
B 1 509 THR 509 498 498 THR THR B . n 
B 1 510 ILE 510 499 499 ILE ILE B . n 
B 1 511 VAL 511 500 500 VAL VAL B . n 
B 1 512 PHE 512 501 501 PHE PHE B . n 
B 1 513 ARG 513 502 502 ARG ARG B . n 
B 1 514 THR 514 503 503 THR THR B . n 
B 1 515 GLN 515 504 504 GLN GLN B . n 
B 1 516 PHE 516 505 505 PHE PHE B . n 
B 1 517 PRO 517 506 506 PRO PRO B . n 
B 1 518 LYS 518 507 507 LYS LYS B . n 
B 1 519 CYS 519 508 508 CYS CYS B . n 
B 1 520 SER 520 509 509 SER SER B . n 
B 1 521 THR 521 510 510 THR THR B . n 
B 1 522 LEU 522 511 511 LEU LEU B . n 
B 1 523 ALA 523 512 512 ALA ALA B . n 
B 1 524 ASN 524 513 513 ASN ASN B . n 
B 1 525 ILE 525 514 514 ILE ILE B . n 
B 1 526 GLY 526 515 515 GLY GLY B . n 
B 1 527 ARG 527 516 516 ARG ARG B . n 
B 1 528 THR 528 517 517 THR THR B . n 
B 1 529 ASN 529 518 518 ASN ASN B . n 
B 1 530 ILE 530 519 519 ILE ILE B . n 
B 1 531 TYR 531 520 520 TYR TYR B . n 
B 1 532 LYS 532 521 521 LYS LYS B . n 
B 1 533 ASN 533 522 522 ASN ASN B . n 
B 1 534 LYS 534 523 523 LYS LYS B . n 
B 1 535 LYS 535 524 524 LYS LYS B . n 
B 1 536 ASP 536 525 525 ASP ASP B . n 
B 1 537 TYR 537 526 526 TYR TYR B . n 
B 1 538 TYR 538 527 527 TYR TYR B . n 
B 1 539 ASP 539 528 528 ASP ASP B . n 
B 1 540 MET 540 529 529 MET MET B . n 
B 1 541 TYR 541 530 530 TYR TYR B . n 
B 1 542 GLU 542 531 531 GLU GLU B . n 
B 1 543 PRO 543 532 532 PRO PRO B . n 
B 1 544 GLU 544 533 533 GLU GLU B . n 
B 1 545 GLY 545 534 534 GLY GLY B . n 
B 1 546 VAL 546 535 535 VAL VAL B . n 
B 1 547 LYS 547 536 536 LYS LYS B . n 
B 1 548 ILE 548 537 537 ILE ILE B . n 
B 1 549 PHE 549 538 538 PHE PHE B . n 
B 1 550 ARG 550 539 539 ARG ARG B . n 
B 1 551 CYS 551 540 540 CYS CYS B . n 
B 1 552 PRO 552 541 541 PRO PRO B . n 
B 1 553 SER 553 542 542 SER SER B . n 
B 1 554 PRO 554 543 543 PRO PRO B . n 
B 1 555 ILE 555 544 544 ILE ILE B . n 
B 1 556 TYR 556 545 545 TYR TYR B . n 
B 1 557 PHE 557 546 546 PHE PHE B . n 
B 1 558 ALA 558 547 547 ALA ALA B . n 
B 1 559 ASN 559 548 548 ASN ASN B . n 
B 1 560 ILE 560 549 549 ILE ILE B . n 
B 1 561 GLY 561 550 550 GLY GLY B . n 
B 1 562 PHE 562 551 551 PHE PHE B . n 
B 1 563 PHE 563 552 552 PHE PHE B . n 
B 1 564 ARG 564 553 553 ARG ARG B . n 
B 1 565 ARG 565 554 554 ARG ARG B . n 
B 1 566 LYS 566 555 555 LYS LYS B . n 
B 1 567 LEU 567 556 556 LEU LEU B . n 
B 1 568 ILE 568 557 557 ILE ILE B . n 
B 1 569 ASP 569 558 558 ASP ASP B . n 
B 1 570 ALA 570 559 559 ALA ALA B . n 
B 1 571 VAL 571 560 560 VAL VAL B . n 
B 1 572 GLY 572 561 561 GLY GLY B . n 
B 1 573 PHE 573 562 562 PHE PHE B . n 
B 1 574 SER 574 563 563 SER SER B . n 
B 1 575 PRO 575 564 564 PRO PRO B . n 
B 1 576 LEU 576 565 565 LEU LEU B . n 
B 1 577 ARG 577 566 566 ARG ARG B . n 
B 1 578 ILE 578 567 567 ILE ILE B . n 
B 1 579 LEU 579 568 568 LEU LEU B . n 
B 1 580 ARG 580 569 569 ARG ARG B . n 
B 1 581 LYS 581 570 570 LYS LYS B . n 
B 1 582 ARG 582 571 571 ARG ARG B . n 
B 1 583 ASN 583 572 572 ASN ASN B . n 
B 1 584 LYS 584 573 573 LYS LYS B . n 
B 1 585 ALA 585 574 574 ALA ALA B . n 
B 1 586 LEU 586 575 575 LEU LEU B . n 
B 1 587 ARG 587 576 576 ARG ARG B . n 
B 1 588 LYS 588 577 577 LYS LYS B . n 
B 1 589 ILE 589 578 578 ILE ILE B . n 
B 1 590 ARG 590 579 579 ARG ARG B . n 
B 1 591 LYS 591 580 580 LYS LYS B . n 
B 1 592 LEU 592 581 581 LEU LEU B . n 
B 1 593 GLN 593 582 582 GLN GLN B . n 
B 1 594 LYS 594 583 583 LYS LYS B . n 
B 1 595 GLN 595 584 584 GLN GLN B . n 
B 1 596 GLY 596 585 585 GLY GLY B . n 
B 1 597 LEU 597 586 586 LEU LEU B . n 
B 1 598 LEU 598 587 587 LEU LEU B . n 
B 1 599 GLN 599 588 588 GLN GLN B . n 
B 1 600 VAL 600 589 589 VAL VAL B . n 
B 1 601 THR 601 590 590 THR THR B . n 
B 1 602 PRO 602 591 591 PRO PRO B . n 
B 1 603 LYS 603 592 592 LYS LYS B . n 
B 1 604 GLY 604 593 593 GLY GLY B . n 
B 1 605 PHE 605 594 594 PHE PHE B . n 
B 1 606 ILE 606 595 595 ILE ILE B . n 
B 1 607 CYS 607 596 596 CYS CYS B . n 
B 1 608 THR 608 597 597 THR THR B . n 
B 1 609 VAL 609 598 598 VAL VAL B . n 
B 1 610 ASP 610 599 599 ASP ASP B . n 
B 1 611 THR 611 600 600 THR THR B . n 
B 1 612 ILE 612 601 601 ILE ILE B . n 
B 1 613 LYS 613 602 602 LYS LYS B . n 
B 1 614 ASP 614 603 603 ASP ASP B . n 
B 1 615 SER 615 604 604 SER SER B . n 
B 1 616 ASP 616 605 605 ASP ASP B . n 
B 1 617 GLU 617 606 606 GLU GLU B . n 
B 1 618 GLU 618 607 607 GLU GLU B . n 
B 1 619 LEU 619 608 608 LEU LEU B . n 
B 1 620 ASP 620 609 609 ASP ASP B . n 
B 1 621 ASN 621 610 610 ASN ASN B . n 
B 1 622 ASN 622 611 611 ASN ASN B . n 
B 1 623 GLN 623 612 612 GLN GLN B . n 
B 1 624 ILE 624 613 613 ILE ILE B . n 
B 1 625 GLU 625 614 614 GLU GLU B . n 
B 1 626 VAL 626 615 615 VAL VAL B . n 
B 1 627 LEU 627 616 616 LEU LEU B . n 
B 1 628 ASP 628 617 617 ASP ASP B . n 
B 1 629 GLN 629 618 618 GLN GLN B . n 
B 1 630 PRO 630 619 619 PRO PRO B . n 
B 1 631 ILE 631 620 620 ILE ILE B . n 
B 1 632 ASN 632 621 621 ASN ASN B . n 
B 1 633 THR 633 622 622 THR THR B . n 
B 1 634 THR 634 623 623 THR THR B . n 
B 1 635 ASP 635 624 624 ASP ASP B . n 
B 1 636 LEU 636 625 625 LEU LEU B . n 
B 1 637 PRO 637 626 626 PRO PRO B . n 
B 1 638 PHE 638 627 627 PHE PHE B . n 
B 1 639 HIS 639 628 628 HIS HIS B . n 
B 1 640 ILE 640 629 629 ILE ILE B . n 
B 1 641 ASP 641 630 630 ASP ASP B . n 
B 1 642 TRP 642 631 631 TRP TRP B . n 
B 1 643 ASN 643 632 632 ASN ASN B . n 
B 1 644 ASP 644 633 633 ASP ASP B . n 
B 1 645 ASP 645 634 634 ASP ASP B . n 
B 1 646 LEU 646 635 635 LEU LEU B . n 
B 1 647 PRO 647 636 636 PRO PRO B . n 
B 1 648 LEU 648 637 637 LEU LEU B . n 
B 1 649 ASN 649 638 638 ASN ASN B . n 
B 1 650 ILE 650 639 639 ILE ILE B . n 
B 1 651 GLU 651 640 640 GLU GLU B . n 
B 1 652 VAL 652 641 641 VAL VAL B . n 
B 1 653 PRO 653 642 642 PRO PRO B . n 
B 1 654 LYS 654 643 643 LYS LYS B . n 
B 1 655 ILE 655 644 644 ILE ILE B . n 
B 1 656 SER 656 645 645 SER SER B . n 
B 1 657 LEU 657 646 646 LEU LEU B . n 
B 1 658 HIS 658 647 647 HIS HIS B . n 
B 1 659 SER 659 648 648 SER SER B . n 
B 1 660 LEU 660 649 649 LEU LEU B . n 
B 1 661 ILE 661 650 650 ILE ILE B . n 
B 1 662 LEU 662 651 651 LEU LEU B . n 
B 1 663 ASP 663 652 652 ASP ASP B . n 
B 1 664 PHE 664 653 653 PHE PHE B . n 
B 1 665 SER 665 654 654 SER SER B . n 
B 1 666 ALA 666 655 655 ALA ALA B . n 
B 1 667 VAL 667 656 656 VAL VAL B . n 
B 1 668 SER 668 657 657 SER SER B . n 
B 1 669 PHE 669 658 658 PHE PHE B . n 
B 1 670 LEU 670 659 659 LEU LEU B . n 
B 1 671 ASP 671 660 660 ASP ASP B . n 
B 1 672 VAL 672 661 661 VAL VAL B . n 
B 1 673 SER 673 662 662 SER SER B . n 
B 1 674 SER 674 663 663 SER SER B . n 
B 1 675 VAL 675 664 664 VAL VAL B . n 
B 1 676 ARG 676 665 665 ARG ARG B . n 
B 1 677 GLY 677 666 666 GLY GLY B . n 
B 1 678 LEU 678 667 667 LEU LEU B . n 
B 1 679 LYS 679 668 668 LYS LYS B . n 
B 1 680 SER 680 669 669 SER SER B . n 
B 1 681 ILE 681 670 670 ILE ILE B . n 
B 1 682 LEU 682 671 671 LEU LEU B . n 
B 1 683 GLN 683 672 672 GLN GLN B . n 
B 1 684 GLU 684 673 673 GLU GLU B . n 
B 1 685 PHE 685 674 674 PHE PHE B . n 
B 1 686 ILE 686 675 675 ILE ILE B . n 
B 1 687 ARG 687 676 676 ARG ARG B . n 
B 1 688 ILE 688 677 677 ILE ILE B . n 
B 1 689 LYS 689 678 678 LYS LYS B . n 
B 1 690 VAL 690 679 679 VAL VAL B . n 
B 1 691 ASP 691 680 680 ASP ASP B . n 
B 1 692 VAL 692 681 681 VAL VAL B . n 
B 1 693 TYR 693 682 682 TYR TYR B . n 
B 1 694 ILE 694 683 683 ILE ILE B . n 
B 1 695 VAL 695 684 684 VAL VAL B . n 
B 1 696 GLY 696 685 685 GLY GLY B . n 
B 1 697 THR 697 686 686 THR THR B . n 
B 1 698 ASP 698 687 687 ASP ASP B . n 
B 1 699 ASP 699 688 688 ASP ASP B . n 
B 1 700 ASP 700 689 689 ASP ASP B . n 
B 1 701 PHE 701 690 690 PHE PHE B . n 
B 1 702 ILE 702 691 691 ILE ILE B . n 
B 1 703 GLU 703 692 692 GLU GLU B . n 
B 1 704 LYS 704 693 693 LYS LYS B . n 
B 1 705 LEU 705 694 694 LEU LEU B . n 
B 1 706 ASN 706 695 695 ASN ASN B . n 
B 1 707 ARG 707 696 696 ARG ARG B . n 
B 1 708 TYR 708 697 697 TYR TYR B . n 
B 1 709 GLU 709 698 698 GLU GLU B . n 
B 1 710 PHE 710 699 699 PHE PHE B . n 
B 1 711 PHE 711 700 700 PHE PHE B . n 
B 1 712 ASP 712 701 701 ASP ASP B . n 
B 1 713 GLY 713 702 702 GLY GLY B . n 
B 1 714 GLU 714 703 703 GLU GLU B . n 
B 1 715 VAL 715 704 704 VAL VAL B . n 
B 1 716 LYS 716 705 705 LYS LYS B . n 
B 1 717 SER 717 706 706 SER SER B . n 
B 1 718 SER 718 707 707 SER SER B . n 
B 1 719 ILE 719 708 708 ILE ILE B . n 
B 1 720 PHE 720 709 709 PHE PHE B . n 
B 1 721 PHE 721 710 710 PHE PHE B . n 
B 1 722 LEU 722 711 711 LEU LEU B . n 
B 1 723 THR 723 712 712 THR THR B . n 
B 1 724 ILE 724 713 713 ILE ILE B . n 
B 1 725 HIS 725 714 714 HIS HIS B . n 
B 1 726 ASP 726 715 715 ASP ASP B . n 
B 1 727 ALA 727 716 716 ALA ALA B . n 
B 1 728 VAL 728 717 717 VAL VAL B . n 
B 1 729 LEU 729 718 718 LEU LEU B . n 
B 1 730 HIS 730 719 719 HIS HIS B . n 
B 1 731 ILE 731 720 720 ILE ILE B . n 
B 1 732 LEU 732 721 721 LEU LEU B . n 
B 1 733 MET 733 722 722 MET MET B . n 
B 1 734 LYS 734 723 723 LYS LYS B . n 
B 1 735 LYS 735 724 724 LYS LYS B . n 
B 1 736 ASP 736 725 725 ASP ASP B . n 
B 1 737 TYR 737 726 ?   ?   ?   B . n 
B 1 738 SER 738 727 ?   ?   ?   B . n 
B 1 739 THR 739 728 ?   ?   ?   B . n 
B 1 740 SER 740 729 ?   ?   ?   B . n 
B 1 741 LYS 741 730 ?   ?   ?   B . n 
B 1 742 PHE 742 731 ?   ?   ?   B . n 
B 1 743 ASN 743 732 ?   ?   ?   B . n 
B 1 744 PRO 744 733 ?   ?   ?   B . n 
B 1 745 SER 745 734 ?   ?   ?   B . n 
B 1 746 GLN 746 735 ?   ?   ?   B . n 
B 1 747 GLU 747 736 ?   ?   ?   B . n 
B 1 748 LYS 748 737 ?   ?   ?   B . n 
B 1 749 ASP 749 738 ?   ?   ?   B . n 
B 1 750 GLY 750 739 ?   ?   ?   B . n 
B 1 751 LYS 751 740 ?   ?   ?   B . n 
B 1 752 ILE 752 741 ?   ?   ?   B . n 
B 1 753 ASP 753 742 ?   ?   ?   B . n 
B 1 754 PHE 754 743 ?   ?   ?   B . n 
B 1 755 THR 755 744 ?   ?   ?   B . n 
B 1 756 ILE 756 745 ?   ?   ?   B . n 
B 1 757 ASN 757 746 ?   ?   ?   B . n 
B 1 758 THR 758 747 ?   ?   ?   B . n 
B 1 759 ASN 759 748 ?   ?   ?   B . n 
B 1 760 GLY 760 749 ?   ?   ?   B . n 
B 1 761 GLY 761 750 ?   ?   ?   B . n 
B 1 762 LEU 762 751 ?   ?   ?   B . n 
B 1 763 ARG 763 752 ?   ?   ?   B . n 
B 1 764 ASN 764 753 ?   ?   ?   B . n 
B 1 765 ARG 765 754 ?   ?   ?   B . n 
B 1 766 VAL 766 755 ?   ?   ?   B . n 
B 1 767 TYR 767 756 ?   ?   ?   B . n 
B 1 768 GLU 768 757 ?   ?   ?   B . n 
B 1 769 VAL 769 758 ?   ?   ?   B . n 
B 1 770 PRO 770 759 ?   ?   ?   B . n 
B 1 771 VAL 771 760 ?   ?   ?   B . n 
B 1 772 GLU 772 761 ?   ?   ?   B . n 
B 1 773 THR 773 762 ?   ?   ?   B . n 
B 1 774 LYS 774 763 ?   ?   ?   B . n 
B 1 775 PHE 775 764 ?   ?   ?   B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 CL  ? ? CL  ? ? 'SUBJECT OF INVESTIGATION' ? 
2 LPE ? ? LPE ? ? 'SUBJECT OF INVESTIGATION' ? 
3 I2U ? ? I2U ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 CL  1 801 815 CL  CL  A . 
D 3 LPE 1 802 901 LPE LPE A . 
E 4 I2U 1 803 2   I2U TEN A . 
F 2 CL  1 801 815 CL  CL  B . 
G 3 LPE 1 802 901 LPE LPE B . 
H 4 I2U 1 803 1   I2U TEN B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ARG 30  ? CG  ? A ARG 41  CG  
2  1 Y 1 A ARG 30  ? CD  ? A ARG 41  CD  
3  1 Y 1 A ARG 30  ? NE  ? A ARG 41  NE  
4  1 Y 1 A ARG 30  ? CZ  ? A ARG 41  CZ  
5  1 Y 1 A ARG 30  ? NH1 ? A ARG 41  NH1 
6  1 Y 1 A ARG 30  ? NH2 ? A ARG 41  NH2 
7  1 Y 1 A LYS 33  ? CG  ? A LYS 44  CG  
8  1 Y 1 A LYS 33  ? CD  ? A LYS 44  CD  
9  1 Y 1 A LYS 33  ? CE  ? A LYS 44  CE  
10 1 Y 1 A LYS 33  ? NZ  ? A LYS 44  NZ  
11 1 Y 1 A ASP 284 ? CG  ? A ASP 295 CG  
12 1 Y 1 A ASP 284 ? OD1 ? A ASP 295 OD1 
13 1 Y 1 A ASP 284 ? OD2 ? A ASP 295 OD2 
14 1 Y 1 A LYS 285 ? CG  ? A LYS 296 CG  
15 1 Y 1 A LYS 285 ? CD  ? A LYS 296 CD  
16 1 Y 1 A LYS 285 ? CE  ? A LYS 296 CE  
17 1 Y 1 A LYS 285 ? NZ  ? A LYS 296 NZ  
18 1 Y 1 A ILE 601 ? CG1 ? A ILE 612 CG1 
19 1 Y 1 A ILE 601 ? CG2 ? A ILE 612 CG2 
20 1 Y 1 A ILE 601 ? CD1 ? A ILE 612 CD1 
21 1 Y 1 B ARG 30  ? CG  ? B ARG 41  CG  
22 1 Y 1 B ARG 30  ? CD  ? B ARG 41  CD  
23 1 Y 1 B ARG 30  ? NE  ? B ARG 41  NE  
24 1 Y 1 B ARG 30  ? CZ  ? B ARG 41  CZ  
25 1 Y 1 B ARG 30  ? NH1 ? B ARG 41  NH1 
26 1 Y 1 B ARG 30  ? NH2 ? B ARG 41  NH2 
27 1 Y 1 B LYS 33  ? CG  ? B LYS 44  CG  
28 1 Y 1 B LYS 33  ? CD  ? B LYS 44  CD  
29 1 Y 1 B LYS 33  ? CE  ? B LYS 44  CE  
30 1 Y 1 B LYS 33  ? NZ  ? B LYS 44  NZ  
31 1 Y 1 B ASP 284 ? CG  ? B ASP 295 CG  
32 1 Y 1 B ASP 284 ? OD1 ? B ASP 295 OD1 
33 1 Y 1 B ASP 284 ? OD2 ? B ASP 295 OD2 
34 1 Y 1 B LYS 285 ? CG  ? B LYS 296 CG  
35 1 Y 1 B LYS 285 ? CD  ? B LYS 296 CD  
36 1 Y 1 B LYS 285 ? CE  ? B LYS 296 CE  
37 1 Y 1 B LYS 285 ? NZ  ? B LYS 296 NZ  
38 1 N 1 A LPE 802 ? C19 ? D LPE 1   C19 
39 1 N 1 A LPE 802 ? C20 ? D LPE 1   C20 
40 1 N 1 A LPE 802 ? C21 ? D LPE 1   C21 
41 1 N 1 A LPE 802 ? C22 ? D LPE 1   C22 
42 1 N 1 A LPE 802 ? C23 ? D LPE 1   C23 
43 1 N 1 A LPE 802 ? C24 ? D LPE 1   C24 
44 1 N 1 A LPE 802 ? C25 ? D LPE 1   C25 
45 1 N 1 A LPE 802 ? C26 ? D LPE 1   C26 
46 1 N 1 A LPE 802 ? C27 ? D LPE 1   C27 
47 1 N 1 A LPE 802 ? C28 ? D LPE 1   C28 
48 1 N 1 B LPE 802 ? C19 ? G LPE 1   C19 
49 1 N 1 B LPE 802 ? C20 ? G LPE 1   C20 
50 1 N 1 B LPE 802 ? C21 ? G LPE 1   C21 
51 1 N 1 B LPE 802 ? C22 ? G LPE 1   C22 
52 1 N 1 B LPE 802 ? C23 ? G LPE 1   C23 
53 1 N 1 B LPE 802 ? C24 ? G LPE 1   C24 
54 1 N 1 B LPE 802 ? C25 ? G LPE 1   C25 
55 1 N 1 B LPE 802 ? C26 ? G LPE 1   C26 
56 1 N 1 B LPE 802 ? C27 ? G LPE 1   C27 
57 1 N 1 B LPE 802 ? C28 ? G LPE 1   C28 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8X1S 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8X1S 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8X1S 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8X1S 
_struct.title                        'Cryo-EM structure of human DRA (SLC26A3) bound with tenidap' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8X1S 
_struct_keywords.text            'DRA, SLC26A3, tenidap, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
F N N 2 ? 
G N N 3 ? 
H N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    S26A3_HUMAN 
_struct_ref.pdbx_db_accession          P40879 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSG
ISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLP
NNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDP
VSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRFKVAVVGD
MNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRS
AVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTI
VLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAV
GFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIE
VPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHI
LMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8X1S A 12 ? 775 ? P40879 1 ? 764 ? 1 764 
2 1 8X1S B 12 ? 775 ? P40879 1 ? 764 ? 1 764 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8X1S MET A 1  ? UNP P40879 ? ? 'initiating methionine' -10 1  
1 8X1S ASP A 2  ? UNP P40879 ? ? 'expression tag'        -9  2  
1 8X1S TYR A 3  ? UNP P40879 ? ? 'expression tag'        -8  3  
1 8X1S LYS A 4  ? UNP P40879 ? ? 'expression tag'        -7  4  
1 8X1S ASP A 5  ? UNP P40879 ? ? 'expression tag'        -6  5  
1 8X1S ASP A 6  ? UNP P40879 ? ? 'expression tag'        -5  6  
1 8X1S ASP A 7  ? UNP P40879 ? ? 'expression tag'        -4  7  
1 8X1S ASP A 8  ? UNP P40879 ? ? 'expression tag'        -3  8  
1 8X1S LYS A 9  ? UNP P40879 ? ? 'expression tag'        -2  9  
1 8X1S GLY A 10 ? UNP P40879 ? ? 'expression tag'        -1  10 
1 8X1S THR A 11 ? UNP P40879 ? ? 'expression tag'        0   11 
2 8X1S MET B 1  ? UNP P40879 ? ? 'initiating methionine' -10 12 
2 8X1S ASP B 2  ? UNP P40879 ? ? 'expression tag'        -9  13 
2 8X1S TYR B 3  ? UNP P40879 ? ? 'expression tag'        -8  14 
2 8X1S LYS B 4  ? UNP P40879 ? ? 'expression tag'        -7  15 
2 8X1S ASP B 5  ? UNP P40879 ? ? 'expression tag'        -6  16 
2 8X1S ASP B 6  ? UNP P40879 ? ? 'expression tag'        -5  17 
2 8X1S ASP B 7  ? UNP P40879 ? ? 'expression tag'        -4  18 
2 8X1S ASP B 8  ? UNP P40879 ? ? 'expression tag'        -3  19 
2 8X1S LYS B 9  ? UNP P40879 ? ? 'expression tag'        -2  20 
2 8X1S GLY B 10 ? UNP P40879 ? ? 'expression tag'        -1  21 
2 8X1S THR B 11 ? UNP P40879 ? ? 'expression tag'        0   22 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 28  ? HIS A 36  ? SER A 17  HIS A 25  1 ? 9  
HELX_P HELX_P2  AA2 THR A 45  ? CYS A 54  ? THR A 34  CYS A 43  1 ? 10 
HELX_P HELX_P3  AA3 SER A 57  ? PHE A 69  ? SER A 46  PHE A 58  1 ? 13 
HELX_P HELX_P4  AA4 PRO A 70  ? LEU A 75  ? PRO A 59  LEU A 64  1 ? 6  
HELX_P HELX_P5  AA5 ARG A 79  ? ASP A 110 ? ARG A 68  ASP A 99  1 ? 32 
HELX_P HELX_P6  AA6 PRO A 113 ? GLY A 131 ? PRO A 102 GLY A 120 1 ? 19 
HELX_P HELX_P7  AA7 PHE A 141 ? LYS A 158 ? PHE A 130 LYS A 147 1 ? 18 
HELX_P HELX_P8  AA8 LEU A 180 ? LEU A 207 ? LEU A 169 LEU A 196 1 ? 28 
HELX_P HELX_P9  AA9 ILE A 209 ? LEU A 216 ? ILE A 198 LEU A 205 5 ? 8  
HELX_P HELX_P10 AB1 SER A 217 ? GLN A 236 ? SER A 206 GLN A 225 1 ? 20 
HELX_P HELX_P11 AB2 GLN A 236 ? PHE A 241 ? GLN A 225 PHE A 230 1 ? 6  
HELX_P HELX_P12 AB3 VAL A 252 ? GLN A 264 ? VAL A 241 GLN A 253 1 ? 13 
HELX_P HELX_P13 AB4 ILE A 265 ? THR A 268 ? ILE A 254 THR A 257 5 ? 4  
HELX_P HELX_P14 AB5 ASN A 269 ? PHE A 293 ? ASN A 258 PHE A 282 1 ? 25 
HELX_P HELX_P15 AB6 PRO A 302 ? CYS A 318 ? PRO A 291 CYS A 307 1 ? 17 
HELX_P HELX_P16 AB7 ASP A 319 ? LYS A 325 ? ASP A 308 LYS A 314 1 ? 7  
HELX_P HELX_P17 AB8 ASP A 343 ? ASP A 377 ? ASP A 332 ASP A 366 1 ? 35 
HELX_P HELX_P18 AB9 ASP A 381 ? PHE A 399 ? ASP A 370 PHE A 388 1 ? 19 
HELX_P HELX_P19 AC1 ALA A 407 ? THR A 417 ? ALA A 396 THR A 406 1 ? 11 
HELX_P HELX_P20 AC2 GLN A 422 ? ALA A 438 ? GLN A 411 ALA A 427 1 ? 17 
HELX_P HELX_P21 AC3 ILE A 439 ? ALA A 444 ? ILE A 428 ALA A 433 5 ? 6  
HELX_P HELX_P22 AC4 GLN A 447 ? ASN A 458 ? GLN A 436 ASN A 447 1 ? 12 
HELX_P HELX_P23 AC5 ASN A 458 ? MET A 464 ? ASN A 447 MET A 453 1 ? 7  
HELX_P HELX_P24 AC6 ALA A 467 ? ASP A 476 ? ALA A 456 ASP A 465 1 ? 10 
HELX_P HELX_P25 AC7 ASP A 476 ? LEU A 493 ? ASP A 465 LEU A 482 1 ? 18 
HELX_P HELX_P26 AC8 GLY A 494 ? GLN A 515 ? GLY A 483 GLN A 504 1 ? 22 
HELX_P HELX_P27 AC9 ASN A 559 ? GLY A 572 ? ASN A 548 GLY A 561 1 ? 14 
HELX_P HELX_P28 AD1 SER A 574 ? GLY A 596 ? SER A 563 GLY A 585 1 ? 23 
HELX_P HELX_P29 AD2 GLN A 623 ? GLN A 629 ? GLN A 612 GLN A 618 5 ? 7  
HELX_P HELX_P30 AD3 LEU A 646 ? ILE A 650 ? LEU A 635 ILE A 639 5 ? 5  
HELX_P HELX_P31 AD4 ASP A 671 ? ILE A 688 ? ASP A 660 ILE A 677 1 ? 18 
HELX_P HELX_P32 AD5 ASP A 698 ? TYR A 708 ? ASP A 687 TYR A 697 1 ? 11 
HELX_P HELX_P33 AD6 LYS A 716 ? SER A 718 ? LYS A 705 SER A 707 5 ? 3  
HELX_P HELX_P34 AD7 THR A 723 ? ASP A 736 ? THR A 712 ASP A 725 1 ? 14 
HELX_P HELX_P35 AD8 SER B 28  ? HIS B 36  ? SER B 17  HIS B 25  1 ? 9  
HELX_P HELX_P36 AD9 THR B 45  ? CYS B 54  ? THR B 34  CYS B 43  1 ? 10 
HELX_P HELX_P37 AE1 SER B 57  ? PHE B 69  ? SER B 46  PHE B 58  1 ? 13 
HELX_P HELX_P38 AE2 PRO B 70  ? LEU B 75  ? PRO B 59  LEU B 64  1 ? 6  
HELX_P HELX_P39 AE3 ARG B 79  ? ASP B 110 ? ARG B 68  ASP B 99  1 ? 32 
HELX_P HELX_P40 AE4 PRO B 113 ? GLY B 131 ? PRO B 102 GLY B 120 1 ? 19 
HELX_P HELX_P41 AE5 PHE B 141 ? ALA B 159 ? PHE B 130 ALA B 148 1 ? 19 
HELX_P HELX_P42 AE6 LEU B 180 ? LEU B 207 ? LEU B 169 LEU B 196 1 ? 28 
HELX_P HELX_P43 AE7 ILE B 209 ? LEU B 216 ? ILE B 198 LEU B 205 5 ? 8  
HELX_P HELX_P44 AE8 SER B 217 ? GLN B 236 ? SER B 206 GLN B 225 1 ? 20 
HELX_P HELX_P45 AE9 GLN B 236 ? PHE B 241 ? GLN B 225 PHE B 230 1 ? 6  
HELX_P HELX_P46 AF1 VAL B 252 ? GLN B 264 ? VAL B 241 GLN B 253 1 ? 13 
HELX_P HELX_P47 AF2 ILE B 265 ? THR B 268 ? ILE B 254 THR B 257 5 ? 4  
HELX_P HELX_P48 AF3 ASN B 269 ? PHE B 293 ? ASN B 258 PHE B 282 1 ? 25 
HELX_P HELX_P49 AF4 PRO B 302 ? CYS B 318 ? PRO B 291 CYS B 307 1 ? 17 
HELX_P HELX_P50 AF5 ASP B 319 ? PHE B 324 ? ASP B 308 PHE B 313 1 ? 6  
HELX_P HELX_P51 AF6 ASP B 343 ? ASP B 377 ? ASP B 332 ASP B 366 1 ? 35 
HELX_P HELX_P52 AF7 ASP B 381 ? PHE B 399 ? ASP B 370 PHE B 388 1 ? 19 
HELX_P HELX_P53 AF8 ALA B 407 ? THR B 417 ? ALA B 396 THR B 406 1 ? 11 
HELX_P HELX_P54 AF9 GLN B 422 ? ALA B 438 ? GLN B 411 ALA B 427 1 ? 17 
HELX_P HELX_P55 AG1 ILE B 439 ? ALA B 444 ? ILE B 428 ALA B 433 5 ? 6  
HELX_P HELX_P56 AG2 GLN B 447 ? ASN B 458 ? GLN B 436 ASN B 447 1 ? 12 
HELX_P HELX_P57 AG3 LEU B 459 ? MET B 464 ? LEU B 448 MET B 453 1 ? 6  
HELX_P HELX_P58 AG4 ALA B 467 ? ASP B 476 ? ALA B 456 ASP B 465 1 ? 10 
HELX_P HELX_P59 AG5 ASP B 476 ? LEU B 493 ? ASP B 465 LEU B 482 1 ? 18 
HELX_P HELX_P60 AG6 GLY B 494 ? GLN B 515 ? GLY B 483 GLN B 504 1 ? 22 
HELX_P HELX_P61 AG7 ASN B 559 ? GLY B 572 ? ASN B 548 GLY B 561 1 ? 14 
HELX_P HELX_P62 AG8 SER B 574 ? GLY B 596 ? SER B 563 GLY B 585 1 ? 23 
HELX_P HELX_P63 AG9 GLN B 623 ? GLN B 629 ? GLN B 612 GLN B 618 5 ? 7  
HELX_P HELX_P64 AH1 ASN B 632 ? LEU B 636 ? ASN B 621 LEU B 625 5 ? 5  
HELX_P HELX_P65 AH2 LEU B 646 ? ILE B 650 ? LEU B 635 ILE B 639 5 ? 5  
HELX_P HELX_P66 AH3 ASP B 671 ? ILE B 688 ? ASP B 660 ILE B 677 1 ? 18 
HELX_P HELX_P67 AH4 ASP B 698 ? TYR B 708 ? ASP B 687 TYR B 697 1 ? 11 
HELX_P HELX_P68 AH5 LYS B 716 ? SER B 718 ? LYS B 705 SER B 707 5 ? 3  
HELX_P HELX_P69 AH6 THR B 723 ? ASP B 736 ? THR B 712 ASP B 725 1 ? 14 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ASP 250 A . ? ASP 239 A PRO 251 A ? PRO 240 A 1 20.99 
2 ASP 250 B . ? ASP 239 B PRO 251 B ? PRO 240 B 1 19.68 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 6 ? 
AA3 ? 2 ? 
AA4 ? 6 ? 
AA5 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA2 5 6 ? parallel      
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
AA4 5 6 ? parallel      
AA5 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 19  ? ARG A 24  ? GLN A 8   ARG A 13  
AA1 2 TYR B 20  ? PRO B 25  ? TYR B 9   PRO B 14  
AA2 1 TYR A 531 ? ASN A 533 ? TYR A 520 ASN A 522 
AA2 2 SER A 520 ? ASN A 524 ? SER A 509 ASN A 513 
AA2 3 VAL A 546 ? ARG A 550 ? VAL A 535 ARG A 539 
AA2 4 SER A 659 ? ASP A 663 ? SER A 648 ASP A 652 
AA2 5 ASP A 691 ? VAL A 695 ? ASP A 680 VAL A 684 
AA2 6 PHE A 720 ? PHE A 721 ? PHE A 709 PHE A 710 
AA3 1 GLN A 599 ? VAL A 600 ? GLN A 588 VAL A 589 
AA3 2 PHE A 605 ? ILE A 606 ? PHE A 594 ILE A 595 
AA4 1 TYR B 531 ? ASN B 533 ? TYR B 520 ASN B 522 
AA4 2 SER B 520 ? ASN B 524 ? SER B 509 ASN B 513 
AA4 3 VAL B 546 ? ARG B 550 ? VAL B 535 ARG B 539 
AA4 4 SER B 659 ? ASP B 663 ? SER B 648 ASP B 652 
AA4 5 ASP B 691 ? VAL B 695 ? ASP B 680 VAL B 684 
AA4 6 PHE B 720 ? PHE B 721 ? PHE B 709 PHE B 710 
AA5 1 GLN B 599 ? THR B 601 ? GLN B 588 THR B 590 
AA5 2 GLY B 604 ? ILE B 606 ? GLY B 593 ILE B 595 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ARG A 24  ? N ARG A 13  O TYR B 20  ? O TYR B 9   
AA2 1 2 O LYS A 532 ? O LYS A 521 N ALA A 523 ? N ALA A 512 
AA2 2 3 N SER A 520 ? N SER A 509 O ARG A 550 ? O ARG A 539 
AA2 3 4 N LYS A 547 ? N LYS A 536 O ILE A 661 ? O ILE A 650 
AA2 4 5 N LEU A 662 ? N LEU A 651 O TYR A 693 ? O TYR A 682 
AA2 5 6 N ILE A 694 ? N ILE A 683 O PHE A 721 ? O PHE A 710 
AA3 1 2 N GLN A 599 ? N GLN A 588 O ILE A 606 ? O ILE A 595 
AA4 1 2 O LYS B 532 ? O LYS B 521 N ALA B 523 ? N ALA B 512 
AA4 2 3 N LEU B 522 ? N LEU B 511 O ILE B 548 ? O ILE B 537 
AA4 3 4 N LYS B 547 ? N LYS B 536 O ILE B 661 ? O ILE B 650 
AA4 4 5 N LEU B 662 ? N LEU B 651 O TYR B 693 ? O TYR B 682 
AA4 5 6 N ILE B 694 ? N ILE B 683 O PHE B 721 ? O PHE B 710 
AA5 1 2 N THR B 601 ? N THR B 590 O GLY B 604 ? O GLY B 593 
# 
_pdbx_entry_details.entry_id                   8X1S 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER A 44  ? ? -94.63  -68.19  
2  1 PHE A 110 ? ? -90.46  -63.44  
3  1 PHE A 282 ? ? -107.33 43.28   
4  1 SER A 394 ? ? -120.47 -70.64  
5  1 THR A 517 ? ? -142.24 -159.30 
6  1 PRO A 541 ? ? -80.32  44.27   
7  1 THR A 600 ? ? 34.37   61.08   
8  1 ASN A 638 ? ? 72.47   -0.20   
9  1 ASP A 701 ? ? -161.42 -166.02 
10 1 PHE B 282 ? ? -99.40  37.05   
11 1 THR B 395 ? ? -170.04 147.43  
12 1 ASN B 518 ? ? -76.83  24.83   
13 1 PRO B 541 ? ? -89.80  48.38   
14 1 TYR B 545 ? ? -134.92 -151.81 
15 1 LEU B 586 ? ? -49.97  -13.35  
16 1 THR B 600 ? ? 33.81   58.30   
17 1 GLU B 607 ? ? 36.16   62.12   
18 1 ASP B 630 ? ? -61.44  98.12   
19 1 ASP B 701 ? ? -161.42 -166.06 
20 1 GLU B 703 ? ? 73.74   -4.34   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8X1S 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8X1S 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.37 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               215033 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 DRA 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8X1S 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             900 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           130000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_vitrification.entry_id              8X1S 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   281 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8X1S 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET -10 ? A MET 1   
2   1 Y 1 A ASP -9  ? A ASP 2   
3   1 Y 1 A TYR -8  ? A TYR 3   
4   1 Y 1 A LYS -7  ? A LYS 4   
5   1 Y 1 A ASP -6  ? A ASP 5   
6   1 Y 1 A ASP -5  ? A ASP 6   
7   1 Y 1 A ASP -4  ? A ASP 7   
8   1 Y 1 A ASP -3  ? A ASP 8   
9   1 Y 1 A LYS -2  ? A LYS 9   
10  1 Y 1 A GLY -1  ? A GLY 10  
11  1 Y 1 A THR 0   ? A THR 11  
12  1 Y 1 A MET 1   ? A MET 12  
13  1 Y 1 A ILE 2   ? A ILE 13  
14  1 Y 1 A GLU 3   ? A GLU 14  
15  1 Y 1 A PRO 4   ? A PRO 15  
16  1 Y 1 A PHE 5   ? A PHE 16  
17  1 Y 1 A GLY 6   ? A GLY 17  
18  1 Y 1 A ASP 151 ? A ASP 162 
19  1 Y 1 A ARG 152 ? A ARG 163 
20  1 Y 1 A ASN 153 ? A ASN 164 
21  1 Y 1 A ALA 154 ? A ALA 165 
22  1 Y 1 A THR 155 ? A THR 166 
23  1 Y 1 A THR 156 ? A THR 167 
24  1 Y 1 A LEU 157 ? A LEU 168 
25  1 Y 1 A GLY 158 ? A GLY 169 
26  1 Y 1 A LEU 159 ? A LEU 170 
27  1 Y 1 A PRO 160 ? A PRO 171 
28  1 Y 1 A ASN 161 ? A ASN 172 
29  1 Y 1 A ASN 162 ? A ASN 173 
30  1 Y 1 A SER 163 ? A SER 174 
31  1 Y 1 A ASN 164 ? A ASN 175 
32  1 Y 1 A ASN 165 ? A ASN 176 
33  1 Y 1 A SER 166 ? A SER 177 
34  1 Y 1 A SER 167 ? A SER 178 
35  1 Y 1 A TYR 726 ? A TYR 737 
36  1 Y 1 A SER 727 ? A SER 738 
37  1 Y 1 A THR 728 ? A THR 739 
38  1 Y 1 A SER 729 ? A SER 740 
39  1 Y 1 A LYS 730 ? A LYS 741 
40  1 Y 1 A PHE 731 ? A PHE 742 
41  1 Y 1 A ASN 732 ? A ASN 743 
42  1 Y 1 A PRO 733 ? A PRO 744 
43  1 Y 1 A SER 734 ? A SER 745 
44  1 Y 1 A GLN 735 ? A GLN 746 
45  1 Y 1 A GLU 736 ? A GLU 747 
46  1 Y 1 A LYS 737 ? A LYS 748 
47  1 Y 1 A ASP 738 ? A ASP 749 
48  1 Y 1 A GLY 739 ? A GLY 750 
49  1 Y 1 A LYS 740 ? A LYS 751 
50  1 Y 1 A ILE 741 ? A ILE 752 
51  1 Y 1 A ASP 742 ? A ASP 753 
52  1 Y 1 A PHE 743 ? A PHE 754 
53  1 Y 1 A THR 744 ? A THR 755 
54  1 Y 1 A ILE 745 ? A ILE 756 
55  1 Y 1 A ASN 746 ? A ASN 757 
56  1 Y 1 A THR 747 ? A THR 758 
57  1 Y 1 A ASN 748 ? A ASN 759 
58  1 Y 1 A GLY 749 ? A GLY 760 
59  1 Y 1 A GLY 750 ? A GLY 761 
60  1 Y 1 A LEU 751 ? A LEU 762 
61  1 Y 1 A ARG 752 ? A ARG 763 
62  1 Y 1 A ASN 753 ? A ASN 764 
63  1 Y 1 A ARG 754 ? A ARG 765 
64  1 Y 1 A VAL 755 ? A VAL 766 
65  1 Y 1 A TYR 756 ? A TYR 767 
66  1 Y 1 A GLU 757 ? A GLU 768 
67  1 Y 1 A VAL 758 ? A VAL 769 
68  1 Y 1 A PRO 759 ? A PRO 770 
69  1 Y 1 A VAL 760 ? A VAL 771 
70  1 Y 1 A GLU 761 ? A GLU 772 
71  1 Y 1 A THR 762 ? A THR 773 
72  1 Y 1 A LYS 763 ? A LYS 774 
73  1 Y 1 A PHE 764 ? A PHE 775 
74  1 Y 1 B MET -10 ? B MET 1   
75  1 Y 1 B ASP -9  ? B ASP 2   
76  1 Y 1 B TYR -8  ? B TYR 3   
77  1 Y 1 B LYS -7  ? B LYS 4   
78  1 Y 1 B ASP -6  ? B ASP 5   
79  1 Y 1 B ASP -5  ? B ASP 6   
80  1 Y 1 B ASP -4  ? B ASP 7   
81  1 Y 1 B ASP -3  ? B ASP 8   
82  1 Y 1 B LYS -2  ? B LYS 9   
83  1 Y 1 B GLY -1  ? B GLY 10  
84  1 Y 1 B THR 0   ? B THR 11  
85  1 Y 1 B MET 1   ? B MET 12  
86  1 Y 1 B ILE 2   ? B ILE 13  
87  1 Y 1 B GLU 3   ? B GLU 14  
88  1 Y 1 B PRO 4   ? B PRO 15  
89  1 Y 1 B PHE 5   ? B PHE 16  
90  1 Y 1 B GLY 6   ? B GLY 17  
91  1 Y 1 B ASP 151 ? B ASP 162 
92  1 Y 1 B ARG 152 ? B ARG 163 
93  1 Y 1 B ASN 153 ? B ASN 164 
94  1 Y 1 B ALA 154 ? B ALA 165 
95  1 Y 1 B THR 155 ? B THR 166 
96  1 Y 1 B THR 156 ? B THR 167 
97  1 Y 1 B LEU 157 ? B LEU 168 
98  1 Y 1 B GLY 158 ? B GLY 169 
99  1 Y 1 B LEU 159 ? B LEU 170 
100 1 Y 1 B PRO 160 ? B PRO 171 
101 1 Y 1 B ASN 161 ? B ASN 172 
102 1 Y 1 B ASN 162 ? B ASN 173 
103 1 Y 1 B SER 163 ? B SER 174 
104 1 Y 1 B ASN 164 ? B ASN 175 
105 1 Y 1 B ASN 165 ? B ASN 176 
106 1 Y 1 B SER 166 ? B SER 177 
107 1 Y 1 B SER 167 ? B SER 178 
108 1 Y 1 B TYR 726 ? B TYR 737 
109 1 Y 1 B SER 727 ? B SER 738 
110 1 Y 1 B THR 728 ? B THR 739 
111 1 Y 1 B SER 729 ? B SER 740 
112 1 Y 1 B LYS 730 ? B LYS 741 
113 1 Y 1 B PHE 731 ? B PHE 742 
114 1 Y 1 B ASN 732 ? B ASN 743 
115 1 Y 1 B PRO 733 ? B PRO 744 
116 1 Y 1 B SER 734 ? B SER 745 
117 1 Y 1 B GLN 735 ? B GLN 746 
118 1 Y 1 B GLU 736 ? B GLU 747 
119 1 Y 1 B LYS 737 ? B LYS 748 
120 1 Y 1 B ASP 738 ? B ASP 749 
121 1 Y 1 B GLY 739 ? B GLY 750 
122 1 Y 1 B LYS 740 ? B LYS 751 
123 1 Y 1 B ILE 741 ? B ILE 752 
124 1 Y 1 B ASP 742 ? B ASP 753 
125 1 Y 1 B PHE 743 ? B PHE 754 
126 1 Y 1 B THR 744 ? B THR 755 
127 1 Y 1 B ILE 745 ? B ILE 756 
128 1 Y 1 B ASN 746 ? B ASN 757 
129 1 Y 1 B THR 747 ? B THR 758 
130 1 Y 1 B ASN 748 ? B ASN 759 
131 1 Y 1 B GLY 749 ? B GLY 760 
132 1 Y 1 B GLY 750 ? B GLY 761 
133 1 Y 1 B LEU 751 ? B LEU 762 
134 1 Y 1 B ARG 752 ? B ARG 763 
135 1 Y 1 B ASN 753 ? B ASN 764 
136 1 Y 1 B ARG 754 ? B ARG 765 
137 1 Y 1 B VAL 755 ? B VAL 766 
138 1 Y 1 B TYR 756 ? B TYR 767 
139 1 Y 1 B GLU 757 ? B GLU 768 
140 1 Y 1 B VAL 758 ? B VAL 769 
141 1 Y 1 B PRO 759 ? B PRO 770 
142 1 Y 1 B VAL 760 ? B VAL 771 
143 1 Y 1 B GLU 761 ? B GLU 772 
144 1 Y 1 B THR 762 ? B THR 773 
145 1 Y 1 B LYS 763 ? B LYS 774 
146 1 Y 1 B PHE 764 ? B PHE 775 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CL  CL   CL N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
I2U C10  C  Y N 159 
I2U C13  C  Y N 160 
I2U C15  C  Y N 161 
I2U C17  C  N N 162 
I2U C20  C  Y N 163 
I2U C21  C  Y N 164 
I2U C8   C  Y N 165 
I2U C9   C  Y N 166 
I2U C11  C  Y N 167 
I2U C12  C  Y N 168 
I2U C14  C  N N 169 
I2U C16  C  Y N 170 
I2U C18  C  Y N 171 
I2U C19  C  Y N 172 
I2U N6   N  Y N 173 
I2U N7   N  N N 174 
I2U O3   O  N N 175 
I2U O4   O  N N 176 
I2U O5   O  N N 177 
I2U S2   S  Y N 178 
I2U CL1  CL N N 179 
I2U H2   H  N N 180 
I2U H3   H  N N 181 
I2U H4   H  N N 182 
I2U H5   H  N N 183 
I2U H6   H  N N 184 
I2U H7   H  N N 185 
I2U H8   H  N N 186 
I2U H9   H  N N 187 
I2U H1   H  N N 188 
ILE N    N  N N 189 
ILE CA   C  N S 190 
ILE C    C  N N 191 
ILE O    O  N N 192 
ILE CB   C  N S 193 
ILE CG1  C  N N 194 
ILE CG2  C  N N 195 
ILE CD1  C  N N 196 
ILE OXT  O  N N 197 
ILE H    H  N N 198 
ILE H2   H  N N 199 
ILE HA   H  N N 200 
ILE HB   H  N N 201 
ILE HG12 H  N N 202 
ILE HG13 H  N N 203 
ILE HG21 H  N N 204 
ILE HG22 H  N N 205 
ILE HG23 H  N N 206 
ILE HD11 H  N N 207 
ILE HD12 H  N N 208 
ILE HD13 H  N N 209 
ILE HXT  H  N N 210 
LEU N    N  N N 211 
LEU CA   C  N S 212 
LEU C    C  N N 213 
LEU O    O  N N 214 
LEU CB   C  N N 215 
LEU CG   C  N N 216 
LEU CD1  C  N N 217 
LEU CD2  C  N N 218 
LEU OXT  O  N N 219 
LEU H    H  N N 220 
LEU H2   H  N N 221 
LEU HA   H  N N 222 
LEU HB2  H  N N 223 
LEU HB3  H  N N 224 
LEU HG   H  N N 225 
LEU HD11 H  N N 226 
LEU HD12 H  N N 227 
LEU HD13 H  N N 228 
LEU HD21 H  N N 229 
LEU HD22 H  N N 230 
LEU HD23 H  N N 231 
LEU HXT  H  N N 232 
LPE C1   C  N N 233 
LPE O1   O  N N 234 
LPE C2   C  N R 235 
LPE O2H  O  N N 236 
LPE C3   C  N N 237 
LPE C11  C  N N 238 
LPE C12  C  N N 239 
LPE O3   O  N N 240 
LPE P    P  N R 241 
LPE O31  O  N N 242 
LPE O32  O  N N 243 
LPE O33  O  N N 244 
LPE C31  C  N N 245 
LPE C32  C  N N 246 
LPE N    N  N N 247 
LPE C1N  C  N N 248 
LPE C2N  C  N N 249 
LPE C3N  C  N N 250 
LPE C13  C  N N 251 
LPE C14  C  N N 252 
LPE C15  C  N N 253 
LPE C16  C  N N 254 
LPE C17  C  N N 255 
LPE C18  C  N N 256 
LPE C19  C  N N 257 
LPE C20  C  N N 258 
LPE C21  C  N N 259 
LPE C22  C  N N 260 
LPE C23  C  N N 261 
LPE C24  C  N N 262 
LPE C25  C  N N 263 
LPE C26  C  N N 264 
LPE C27  C  N N 265 
LPE C28  C  N N 266 
LPE H11  H  N N 267 
LPE H12  H  N N 268 
LPE H21  H  N N 269 
LPE HO21 H  N N 270 
LPE H31  H  N N 271 
LPE H32  H  N N 272 
LPE H111 H  N N 273 
LPE H112 H  N N 274 
LPE H121 H  N N 275 
LPE H122 H  N N 276 
LPE HO31 H  N N 277 
LPE H311 H  N N 278 
LPE H312 H  N N 279 
LPE H321 H  N N 280 
LPE H322 H  N N 281 
LPE H1N1 H  N N 282 
LPE H1N2 H  N N 283 
LPE H1N3 H  N N 284 
LPE H2N1 H  N N 285 
LPE H2N2 H  N N 286 
LPE H2N3 H  N N 287 
LPE H3N1 H  N N 288 
LPE H3N2 H  N N 289 
LPE H3N3 H  N N 290 
LPE H131 H  N N 291 
LPE H132 H  N N 292 
LPE H141 H  N N 293 
LPE H142 H  N N 294 
LPE H151 H  N N 295 
LPE H152 H  N N 296 
LPE H161 H  N N 297 
LPE H162 H  N N 298 
LPE H171 H  N N 299 
LPE H172 H  N N 300 
LPE H181 H  N N 301 
LPE H182 H  N N 302 
LPE H191 H  N N 303 
LPE H192 H  N N 304 
LPE H201 H  N N 305 
LPE H202 H  N N 306 
LPE H211 H  N N 307 
LPE H212 H  N N 308 
LPE H221 H  N N 309 
LPE H222 H  N N 310 
LPE H231 H  N N 311 
LPE H232 H  N N 312 
LPE H241 H  N N 313 
LPE H242 H  N N 314 
LPE H251 H  N N 315 
LPE H252 H  N N 316 
LPE H261 H  N N 317 
LPE H262 H  N N 318 
LPE H271 H  N N 319 
LPE H272 H  N N 320 
LPE H281 H  N N 321 
LPE H282 H  N N 322 
LPE H283 H  N N 323 
LYS N    N  N N 324 
LYS CA   C  N S 325 
LYS C    C  N N 326 
LYS O    O  N N 327 
LYS CB   C  N N 328 
LYS CG   C  N N 329 
LYS CD   C  N N 330 
LYS CE   C  N N 331 
LYS NZ   N  N N 332 
LYS OXT  O  N N 333 
LYS H    H  N N 334 
LYS H2   H  N N 335 
LYS HA   H  N N 336 
LYS HB2  H  N N 337 
LYS HB3  H  N N 338 
LYS HG2  H  N N 339 
LYS HG3  H  N N 340 
LYS HD2  H  N N 341 
LYS HD3  H  N N 342 
LYS HE2  H  N N 343 
LYS HE3  H  N N 344 
LYS HZ1  H  N N 345 
LYS HZ2  H  N N 346 
LYS HZ3  H  N N 347 
LYS HXT  H  N N 348 
MET N    N  N N 349 
MET CA   C  N S 350 
MET C    C  N N 351 
MET O    O  N N 352 
MET CB   C  N N 353 
MET CG   C  N N 354 
MET SD   S  N N 355 
MET CE   C  N N 356 
MET OXT  O  N N 357 
MET H    H  N N 358 
MET H2   H  N N 359 
MET HA   H  N N 360 
MET HB2  H  N N 361 
MET HB3  H  N N 362 
MET HG2  H  N N 363 
MET HG3  H  N N 364 
MET HE1  H  N N 365 
MET HE2  H  N N 366 
MET HE3  H  N N 367 
MET HXT  H  N N 368 
PHE N    N  N N 369 
PHE CA   C  N S 370 
PHE C    C  N N 371 
PHE O    O  N N 372 
PHE CB   C  N N 373 
PHE CG   C  Y N 374 
PHE CD1  C  Y N 375 
PHE CD2  C  Y N 376 
PHE CE1  C  Y N 377 
PHE CE2  C  Y N 378 
PHE CZ   C  Y N 379 
PHE OXT  O  N N 380 
PHE H    H  N N 381 
PHE H2   H  N N 382 
PHE HA   H  N N 383 
PHE HB2  H  N N 384 
PHE HB3  H  N N 385 
PHE HD1  H  N N 386 
PHE HD2  H  N N 387 
PHE HE1  H  N N 388 
PHE HE2  H  N N 389 
PHE HZ   H  N N 390 
PHE HXT  H  N N 391 
PRO N    N  N N 392 
PRO CA   C  N S 393 
PRO C    C  N N 394 
PRO O    O  N N 395 
PRO CB   C  N N 396 
PRO CG   C  N N 397 
PRO CD   C  N N 398 
PRO OXT  O  N N 399 
PRO H    H  N N 400 
PRO HA   H  N N 401 
PRO HB2  H  N N 402 
PRO HB3  H  N N 403 
PRO HG2  H  N N 404 
PRO HG3  H  N N 405 
PRO HD2  H  N N 406 
PRO HD3  H  N N 407 
PRO HXT  H  N N 408 
SER N    N  N N 409 
SER CA   C  N S 410 
SER C    C  N N 411 
SER O    O  N N 412 
SER CB   C  N N 413 
SER OG   O  N N 414 
SER OXT  O  N N 415 
SER H    H  N N 416 
SER H2   H  N N 417 
SER HA   H  N N 418 
SER HB2  H  N N 419 
SER HB3  H  N N 420 
SER HG   H  N N 421 
SER HXT  H  N N 422 
THR N    N  N N 423 
THR CA   C  N S 424 
THR C    C  N N 425 
THR O    O  N N 426 
THR CB   C  N R 427 
THR OG1  O  N N 428 
THR CG2  C  N N 429 
THR OXT  O  N N 430 
THR H    H  N N 431 
THR H2   H  N N 432 
THR HA   H  N N 433 
THR HB   H  N N 434 
THR HG1  H  N N 435 
THR HG21 H  N N 436 
THR HG22 H  N N 437 
THR HG23 H  N N 438 
THR HXT  H  N N 439 
TRP N    N  N N 440 
TRP CA   C  N S 441 
TRP C    C  N N 442 
TRP O    O  N N 443 
TRP CB   C  N N 444 
TRP CG   C  Y N 445 
TRP CD1  C  Y N 446 
TRP CD2  C  Y N 447 
TRP NE1  N  Y N 448 
TRP CE2  C  Y N 449 
TRP CE3  C  Y N 450 
TRP CZ2  C  Y N 451 
TRP CZ3  C  Y N 452 
TRP CH2  C  Y N 453 
TRP OXT  O  N N 454 
TRP H    H  N N 455 
TRP H2   H  N N 456 
TRP HA   H  N N 457 
TRP HB2  H  N N 458 
TRP HB3  H  N N 459 
TRP HD1  H  N N 460 
TRP HE1  H  N N 461 
TRP HE3  H  N N 462 
TRP HZ2  H  N N 463 
TRP HZ3  H  N N 464 
TRP HH2  H  N N 465 
TRP HXT  H  N N 466 
TYR N    N  N N 467 
TYR CA   C  N S 468 
TYR C    C  N N 469 
TYR O    O  N N 470 
TYR CB   C  N N 471 
TYR CG   C  Y N 472 
TYR CD1  C  Y N 473 
TYR CD2  C  Y N 474 
TYR CE1  C  Y N 475 
TYR CE2  C  Y N 476 
TYR CZ   C  Y N 477 
TYR OH   O  N N 478 
TYR OXT  O  N N 479 
TYR H    H  N N 480 
TYR H2   H  N N 481 
TYR HA   H  N N 482 
TYR HB2  H  N N 483 
TYR HB3  H  N N 484 
TYR HD1  H  N N 485 
TYR HD2  H  N N 486 
TYR HE1  H  N N 487 
TYR HE2  H  N N 488 
TYR HH   H  N N 489 
TYR HXT  H  N N 490 
VAL N    N  N N 491 
VAL CA   C  N S 492 
VAL C    C  N N 493 
VAL O    O  N N 494 
VAL CB   C  N N 495 
VAL CG1  C  N N 496 
VAL CG2  C  N N 497 
VAL OXT  O  N N 498 
VAL H    H  N N 499 
VAL H2   H  N N 500 
VAL HA   H  N N 501 
VAL HB   H  N N 502 
VAL HG11 H  N N 503 
VAL HG12 H  N N 504 
VAL HG13 H  N N 505 
VAL HG21 H  N N 506 
VAL HG22 H  N N 507 
VAL HG23 H  N N 508 
VAL HXT  H  N N 509 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
I2U N7  C17  sing N N 150 
I2U O3  C11  sing N N 151 
I2U C17 O5   doub N N 152 
I2U C17 N6   sing N N 153 
I2U C11 N6   sing Y N 154 
I2U C11 C10  doub Y N 155 
I2U C21 S2   sing Y N 156 
I2U C21 C20  doub Y N 157 
I2U N6  C9   sing Y N 158 
I2U S2  C18  sing Y N 159 
I2U C20 C19  sing Y N 160 
I2U C18 C19  doub Y N 161 
I2U C18 C14  sing N N 162 
I2U C10 C14  sing N N 163 
I2U C10 C8   sing Y N 164 
I2U C14 O4   doub N N 165 
I2U C9  C8   doub Y N 166 
I2U C9  C13  sing Y N 167 
I2U C8  C12  sing Y N 168 
I2U C13 C16  doub Y N 169 
I2U C12 C15  doub Y N 170 
I2U C16 C15  sing Y N 171 
I2U C15 CL1  sing N N 172 
I2U C13 H2   sing N N 173 
I2U C20 H3   sing N N 174 
I2U C21 H4   sing N N 175 
I2U C12 H5   sing N N 176 
I2U C16 H6   sing N N 177 
I2U C19 H7   sing N N 178 
I2U N7  H8   sing N N 179 
I2U N7  H9   sing N N 180 
I2U O3  H1   sing N N 181 
ILE N   CA   sing N N 182 
ILE N   H    sing N N 183 
ILE N   H2   sing N N 184 
ILE CA  C    sing N N 185 
ILE CA  CB   sing N N 186 
ILE CA  HA   sing N N 187 
ILE C   O    doub N N 188 
ILE C   OXT  sing N N 189 
ILE CB  CG1  sing N N 190 
ILE CB  CG2  sing N N 191 
ILE CB  HB   sing N N 192 
ILE CG1 CD1  sing N N 193 
ILE CG1 HG12 sing N N 194 
ILE CG1 HG13 sing N N 195 
ILE CG2 HG21 sing N N 196 
ILE CG2 HG22 sing N N 197 
ILE CG2 HG23 sing N N 198 
ILE CD1 HD11 sing N N 199 
ILE CD1 HD12 sing N N 200 
ILE CD1 HD13 sing N N 201 
ILE OXT HXT  sing N N 202 
LEU N   CA   sing N N 203 
LEU N   H    sing N N 204 
LEU N   H2   sing N N 205 
LEU CA  C    sing N N 206 
LEU CA  CB   sing N N 207 
LEU CA  HA   sing N N 208 
LEU C   O    doub N N 209 
LEU C   OXT  sing N N 210 
LEU CB  CG   sing N N 211 
LEU CB  HB2  sing N N 212 
LEU CB  HB3  sing N N 213 
LEU CG  CD1  sing N N 214 
LEU CG  CD2  sing N N 215 
LEU CG  HG   sing N N 216 
LEU CD1 HD11 sing N N 217 
LEU CD1 HD12 sing N N 218 
LEU CD1 HD13 sing N N 219 
LEU CD2 HD21 sing N N 220 
LEU CD2 HD22 sing N N 221 
LEU CD2 HD23 sing N N 222 
LEU OXT HXT  sing N N 223 
LPE C1  O1   sing N N 224 
LPE C1  C2   sing N N 225 
LPE C1  H11  sing N N 226 
LPE C1  H12  sing N N 227 
LPE O1  C11  sing N N 228 
LPE C2  O2H  sing N N 229 
LPE C2  C3   sing N N 230 
LPE C2  H21  sing N N 231 
LPE O2H HO21 sing N N 232 
LPE C3  O3   sing N N 233 
LPE C3  H31  sing N N 234 
LPE C3  H32  sing N N 235 
LPE C11 C12  sing N N 236 
LPE C11 H111 sing N N 237 
LPE C11 H112 sing N N 238 
LPE C12 C13  sing N N 239 
LPE C12 H121 sing N N 240 
LPE C12 H122 sing N N 241 
LPE O3  P    sing N N 242 
LPE P   O31  doub N N 243 
LPE P   O32  sing N N 244 
LPE P   O33  sing N N 245 
LPE O32 HO31 sing N N 246 
LPE O33 C31  sing N N 247 
LPE C31 C32  sing N N 248 
LPE C31 H311 sing N N 249 
LPE C31 H312 sing N N 250 
LPE C32 N    sing N N 251 
LPE C32 H321 sing N N 252 
LPE C32 H322 sing N N 253 
LPE N   C1N  sing N N 254 
LPE N   C2N  sing N N 255 
LPE N   C3N  sing N N 256 
LPE C1N H1N1 sing N N 257 
LPE C1N H1N2 sing N N 258 
LPE C1N H1N3 sing N N 259 
LPE C2N H2N1 sing N N 260 
LPE C2N H2N2 sing N N 261 
LPE C2N H2N3 sing N N 262 
LPE C3N H3N1 sing N N 263 
LPE C3N H3N2 sing N N 264 
LPE C3N H3N3 sing N N 265 
LPE C13 C14  sing N N 266 
LPE C13 H131 sing N N 267 
LPE C13 H132 sing N N 268 
LPE C14 C15  sing N N 269 
LPE C14 H141 sing N N 270 
LPE C14 H142 sing N N 271 
LPE C15 C16  sing N N 272 
LPE C15 H151 sing N N 273 
LPE C15 H152 sing N N 274 
LPE C16 C17  sing N N 275 
LPE C16 H161 sing N N 276 
LPE C16 H162 sing N N 277 
LPE C17 C18  sing N N 278 
LPE C17 H171 sing N N 279 
LPE C17 H172 sing N N 280 
LPE C18 C19  sing N N 281 
LPE C18 H181 sing N N 282 
LPE C18 H182 sing N N 283 
LPE C19 C20  sing N N 284 
LPE C19 H191 sing N N 285 
LPE C19 H192 sing N N 286 
LPE C20 C21  sing N N 287 
LPE C20 H201 sing N N 288 
LPE C20 H202 sing N N 289 
LPE C21 C22  sing N N 290 
LPE C21 H211 sing N N 291 
LPE C21 H212 sing N N 292 
LPE C22 C23  sing N N 293 
LPE C22 H221 sing N N 294 
LPE C22 H222 sing N N 295 
LPE C23 C24  sing N N 296 
LPE C23 H231 sing N N 297 
LPE C23 H232 sing N N 298 
LPE C24 C25  sing N N 299 
LPE C24 H241 sing N N 300 
LPE C24 H242 sing N N 301 
LPE C25 C26  sing N N 302 
LPE C25 H251 sing N N 303 
LPE C25 H252 sing N N 304 
LPE C26 C27  sing N N 305 
LPE C26 H261 sing N N 306 
LPE C26 H262 sing N N 307 
LPE C27 C28  sing N N 308 
LPE C27 H271 sing N N 309 
LPE C27 H272 sing N N 310 
LPE C28 H281 sing N N 311 
LPE C28 H282 sing N N 312 
LPE C28 H283 sing N N 313 
LYS N   CA   sing N N 314 
LYS N   H    sing N N 315 
LYS N   H2   sing N N 316 
LYS CA  C    sing N N 317 
LYS CA  CB   sing N N 318 
LYS CA  HA   sing N N 319 
LYS C   O    doub N N 320 
LYS C   OXT  sing N N 321 
LYS CB  CG   sing N N 322 
LYS CB  HB2  sing N N 323 
LYS CB  HB3  sing N N 324 
LYS CG  CD   sing N N 325 
LYS CG  HG2  sing N N 326 
LYS CG  HG3  sing N N 327 
LYS CD  CE   sing N N 328 
LYS CD  HD2  sing N N 329 
LYS CD  HD3  sing N N 330 
LYS CE  NZ   sing N N 331 
LYS CE  HE2  sing N N 332 
LYS CE  HE3  sing N N 333 
LYS NZ  HZ1  sing N N 334 
LYS NZ  HZ2  sing N N 335 
LYS NZ  HZ3  sing N N 336 
LYS OXT HXT  sing N N 337 
MET N   CA   sing N N 338 
MET N   H    sing N N 339 
MET N   H2   sing N N 340 
MET CA  C    sing N N 341 
MET CA  CB   sing N N 342 
MET CA  HA   sing N N 343 
MET C   O    doub N N 344 
MET C   OXT  sing N N 345 
MET CB  CG   sing N N 346 
MET CB  HB2  sing N N 347 
MET CB  HB3  sing N N 348 
MET CG  SD   sing N N 349 
MET CG  HG2  sing N N 350 
MET CG  HG3  sing N N 351 
MET SD  CE   sing N N 352 
MET CE  HE1  sing N N 353 
MET CE  HE2  sing N N 354 
MET CE  HE3  sing N N 355 
MET OXT HXT  sing N N 356 
PHE N   CA   sing N N 357 
PHE N   H    sing N N 358 
PHE N   H2   sing N N 359 
PHE CA  C    sing N N 360 
PHE CA  CB   sing N N 361 
PHE CA  HA   sing N N 362 
PHE C   O    doub N N 363 
PHE C   OXT  sing N N 364 
PHE CB  CG   sing N N 365 
PHE CB  HB2  sing N N 366 
PHE CB  HB3  sing N N 367 
PHE CG  CD1  doub Y N 368 
PHE CG  CD2  sing Y N 369 
PHE CD1 CE1  sing Y N 370 
PHE CD1 HD1  sing N N 371 
PHE CD2 CE2  doub Y N 372 
PHE CD2 HD2  sing N N 373 
PHE CE1 CZ   doub Y N 374 
PHE CE1 HE1  sing N N 375 
PHE CE2 CZ   sing Y N 376 
PHE CE2 HE2  sing N N 377 
PHE CZ  HZ   sing N N 378 
PHE OXT HXT  sing N N 379 
PRO N   CA   sing N N 380 
PRO N   CD   sing N N 381 
PRO N   H    sing N N 382 
PRO CA  C    sing N N 383 
PRO CA  CB   sing N N 384 
PRO CA  HA   sing N N 385 
PRO C   O    doub N N 386 
PRO C   OXT  sing N N 387 
PRO CB  CG   sing N N 388 
PRO CB  HB2  sing N N 389 
PRO CB  HB3  sing N N 390 
PRO CG  CD   sing N N 391 
PRO CG  HG2  sing N N 392 
PRO CG  HG3  sing N N 393 
PRO CD  HD2  sing N N 394 
PRO CD  HD3  sing N N 395 
PRO OXT HXT  sing N N 396 
SER N   CA   sing N N 397 
SER N   H    sing N N 398 
SER N   H2   sing N N 399 
SER CA  C    sing N N 400 
SER CA  CB   sing N N 401 
SER CA  HA   sing N N 402 
SER C   O    doub N N 403 
SER C   OXT  sing N N 404 
SER CB  OG   sing N N 405 
SER CB  HB2  sing N N 406 
SER CB  HB3  sing N N 407 
SER OG  HG   sing N N 408 
SER OXT HXT  sing N N 409 
THR N   CA   sing N N 410 
THR N   H    sing N N 411 
THR N   H2   sing N N 412 
THR CA  C    sing N N 413 
THR CA  CB   sing N N 414 
THR CA  HA   sing N N 415 
THR C   O    doub N N 416 
THR C   OXT  sing N N 417 
THR CB  OG1  sing N N 418 
THR CB  CG2  sing N N 419 
THR CB  HB   sing N N 420 
THR OG1 HG1  sing N N 421 
THR CG2 HG21 sing N N 422 
THR CG2 HG22 sing N N 423 
THR CG2 HG23 sing N N 424 
THR OXT HXT  sing N N 425 
TRP N   CA   sing N N 426 
TRP N   H    sing N N 427 
TRP N   H2   sing N N 428 
TRP CA  C    sing N N 429 
TRP CA  CB   sing N N 430 
TRP CA  HA   sing N N 431 
TRP C   O    doub N N 432 
TRP C   OXT  sing N N 433 
TRP CB  CG   sing N N 434 
TRP CB  HB2  sing N N 435 
TRP CB  HB3  sing N N 436 
TRP CG  CD1  doub Y N 437 
TRP CG  CD2  sing Y N 438 
TRP CD1 NE1  sing Y N 439 
TRP CD1 HD1  sing N N 440 
TRP CD2 CE2  doub Y N 441 
TRP CD2 CE3  sing Y N 442 
TRP NE1 CE2  sing Y N 443 
TRP NE1 HE1  sing N N 444 
TRP CE2 CZ2  sing Y N 445 
TRP CE3 CZ3  doub Y N 446 
TRP CE3 HE3  sing N N 447 
TRP CZ2 CH2  doub Y N 448 
TRP CZ2 HZ2  sing N N 449 
TRP CZ3 CH2  sing Y N 450 
TRP CZ3 HZ3  sing N N 451 
TRP CH2 HH2  sing N N 452 
TRP OXT HXT  sing N N 453 
TYR N   CA   sing N N 454 
TYR N   H    sing N N 455 
TYR N   H2   sing N N 456 
TYR CA  C    sing N N 457 
TYR CA  CB   sing N N 458 
TYR CA  HA   sing N N 459 
TYR C   O    doub N N 460 
TYR C   OXT  sing N N 461 
TYR CB  CG   sing N N 462 
TYR CB  HB2  sing N N 463 
TYR CB  HB3  sing N N 464 
TYR CG  CD1  doub Y N 465 
TYR CG  CD2  sing Y N 466 
TYR CD1 CE1  sing Y N 467 
TYR CD1 HD1  sing N N 468 
TYR CD2 CE2  doub Y N 469 
TYR CD2 HD2  sing N N 470 
TYR CE1 CZ   doub Y N 471 
TYR CE1 HE1  sing N N 472 
TYR CE2 CZ   sing Y N 473 
TYR CE2 HE2  sing N N 474 
TYR CZ  OH   sing N N 475 
TYR OH  HH   sing N N 476 
TYR OXT HXT  sing N N 477 
VAL N   CA   sing N N 478 
VAL N   H    sing N N 479 
VAL N   H2   sing N N 480 
VAL CA  C    sing N N 481 
VAL CA  CB   sing N N 482 
VAL CA  HA   sing N N 483 
VAL C   O    doub N N 484 
VAL C   OXT  sing N N 485 
VAL CB  CG1  sing N N 486 
VAL CB  CG2  sing N N 487 
VAL CB  HB   sing N N 488 
VAL CG1 HG11 sing N N 489 
VAL CG1 HG12 sing N N 490 
VAL CG1 HG13 sing N N 491 
VAL CG2 HG21 sing N N 492 
VAL CG2 HG22 sing N N 493 
VAL CG2 HG23 sing N N 494 
VAL OXT HXT  sing N N 495 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-11-08 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8X1S 
_em_admin.last_update        2025-05-14 
_em_admin.map_release_date   2025-05-14 
_em_admin.title              'Cryo-EM structure of human DRA (SLC26A3) bound with tenidap' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               3.89 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         49.6 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'TFS FALCON 4i (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     2838 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'TFS Selectris X' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?   ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 EPU ? 
MASKING                         ? 3  ? ? ? ?   ? 
'CTF CORRECTION'                ? 4  1 ? ? ?   ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?   ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?   ? 
'MODEL FITTING'                 ? 7  ? ? ? ?   ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ?   ? 
OTHER                           ? 9  ? ? ? ?   ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?   ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?   ? 
CLASSIFICATION                  ? 12 1 ? ? ?   ? 
RECONSTRUCTION                  ? 13 1 ? ? ?   ? 
'VOLUME SELECTION'              ? 14 1 1 1 ?   ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ?   ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?   ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?   ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?   ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?   ? 
# 
_em_specimen.concentration           12 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8X1S 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
N  
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . ASN A 1 18  ? 146.108 127.479 95.955  1.00 55.71  ?  7   ASN A N   1 
ATOM   2     C  CA  . ASN A 1 18  ? 145.417 128.278 96.970  1.00 55.71  ?  7   ASN A CA  1 
ATOM   3     C  C   . ASN A 1 18  ? 145.367 129.768 96.713  1.00 55.71  ?  7   ASN A C   1 
ATOM   4     O  O   . ASN A 1 18  ? 146.379 130.453 96.822  1.00 55.71  ?  7   ASN A O   1 
ATOM   5     C  CB  . ASN A 1 18  ? 146.086 128.045 98.326  1.00 55.71  ?  7   ASN A CB  1 
ATOM   6     C  CG  . ASN A 1 18  ? 147.552 128.427 98.332  1.00 55.71  ?  7   ASN A CG  1 
ATOM   7     O  OD1 . ASN A 1 18  ? 148.222 128.386 97.300  1.00 55.71  ?  7   ASN A OD1 1 
ATOM   8     N  ND2 . ASN A 1 18  ? 148.059 128.798 99.501  1.00 55.71  ?  7   ASN A ND2 1 
ATOM   9     N  N   . GLN A 1 19  ? 144.188 130.289 96.397  1.00 46.84  ?  8   GLN A N   1 
ATOM   10    C  CA  . GLN A 1 19  ? 144.091 131.737 96.245  1.00 46.84  ?  8   GLN A CA  1 
ATOM   11    C  C   . GLN A 1 19  ? 142.947 132.356 97.025  1.00 46.84  ?  8   GLN A C   1 
ATOM   12    O  O   . GLN A 1 19  ? 141.801 131.942 96.894  1.00 46.84  ?  8   GLN A O   1 
ATOM   13    C  CB  . GLN A 1 19  ? 144.012 132.130 94.769  1.00 46.84  ?  8   GLN A CB  1 
ATOM   14    C  CG  . GLN A 1 19  ? 144.566 133.514 94.473  1.00 46.84  ?  8   GLN A CG  1 
ATOM   15    C  CD  . GLN A 1 19  ? 146.072 133.596 94.636  1.00 46.84  ?  8   GLN A CD  1 
ATOM   16    O  OE1 . GLN A 1 19  ? 146.653 134.680 94.581  1.00 46.84  ?  8   GLN A OE1 1 
ATOM   17    N  NE2 . GLN A 1 19  ? 146.713 132.451 94.832  1.00 46.84  ?  8   GLN A NE2 1 
ATOM   18    N  N   . TYR A 1 20  ? 143.266 133.341 97.849  1.00 38.75  ?  9   TYR A N   1 
ATOM   19    C  CA  . TYR A 1 20  ? 142.260 134.053 98.598  1.00 38.75  ?  9   TYR A CA  1 
ATOM   20    C  C   . TYR A 1 20  ? 141.858 135.195 97.701  1.00 38.75  ?  9   TYR A C   1 
ATOM   21    O  O   . TYR A 1 20  ? 142.589 136.166 97.573  1.00 38.75  ?  9   TYR A O   1 
ATOM   22    C  CB  . TYR A 1 20  ? 142.883 134.530 99.903  1.00 38.75  ?  9   TYR A CB  1 
ATOM   23    C  CG  . TYR A 1 20  ? 142.050 135.368 100.840 1.00 38.75  ?  9   TYR A CG  1 
ATOM   24    C  CD1 . TYR A 1 20  ? 141.665 134.871 102.075 1.00 38.75  ?  9   TYR A CD1 1 
ATOM   25    C  CD2 . TYR A 1 20  ? 141.704 136.673 100.524 1.00 38.75  ?  9   TYR A CD2 1 
ATOM   26    C  CE1 . TYR A 1 20  ? 140.929 135.634 102.954 1.00 38.75  ?  9   TYR A CE1 1 
ATOM   27    C  CE2 . TYR A 1 20  ? 140.965 137.443 101.398 1.00 38.75  ?  9   TYR A CE2 1 
ATOM   28    C  CZ  . TYR A 1 20  ? 140.583 136.917 102.611 1.00 38.75  ?  9   TYR A CZ  1 
ATOM   29    O  OH  . TYR A 1 20  ? 139.848 137.674 103.489 1.00 38.75  ?  9   TYR A OH  1 
ATOM   30    N  N   . ILE A 1 21  ? 140.716 135.072 97.042  1.00 40.10  ?  10  ILE A N   1 
ATOM   31    C  CA  . ILE A 1 21  ? 140.255 136.105 96.129  1.00 40.10  ?  10  ILE A CA  1 
ATOM   32    C  C   . ILE A 1 21  ? 138.919 136.670 96.582  1.00 40.10  ?  10  ILE A C   1 
ATOM   33    O  O   . ILE A 1 21  ? 137.943 135.940 96.691  1.00 40.10  ?  10  ILE A O   1 
ATOM   34    C  CB  . ILE A 1 21  ? 140.141 135.561 94.693  1.00 40.10  ?  10  ILE A CB  1 
ATOM   35    C  CG1 . ILE A 1 21  ? 141.489 135.020 94.228  1.00 40.10  ?  10  ILE A CG1 1 
ATOM   36    C  CG2 . ILE A 1 21  ? 139.647 136.646 93.751  1.00 40.10  ?  10  ILE A CG2 1 
ATOM   37    C  CD1 . ILE A 1 21  ? 141.453 134.401 92.851  1.00 40.10  ?  10  ILE A CD1 1 
ATOM   38    N  N   . VAL A 1 22  ? 138.871 137.969 96.840  1.00 39.24  ?  11  VAL A N   1 
ATOM   39    C  CA  . VAL A 1 22  ? 137.645 138.588 97.318  1.00 39.24  ?  11  VAL A CA  1 
ATOM   40    C  C   . VAL A 1 22  ? 137.298 139.859 96.570  1.00 39.24  ?  11  VAL A C   1 
ATOM   41    O  O   . VAL A 1 22  ? 138.167 140.685 96.326  1.00 39.24  ?  11  VAL A O   1 
ATOM   42    C  CB  . VAL A 1 22  ? 137.749 138.919 98.823  1.00 39.24  ?  11  VAL A CB  1 
ATOM   43    C  CG1 . VAL A 1 22  ? 136.547 139.726 99.285  1.00 39.24  ?  11  VAL A CG1 1 
ATOM   44    C  CG2 . VAL A 1 22  ? 137.894 137.649 99.645  1.00 39.24  ?  11  VAL A CG2 1 
ATOM   45    N  N   . ALA A 1 23  ? 136.038 140.021 96.190  1.00 41.84  ?  12  ALA A N   1 
ATOM   46    C  CA  . ALA A 1 23  ? 135.605 141.259 95.547  1.00 41.84  ?  12  ALA A CA  1 
ATOM   47    C  C   . ALA A 1 23  ? 134.254 141.617 96.151  1.00 41.84  ?  12  ALA A C   1 
ATOM   48    O  O   . ALA A 1 23  ? 133.239 141.012 95.808  1.00 41.84  ?  12  ALA A O   1 
ATOM   49    C  CB  . ALA A 1 23  ? 135.520 141.113 94.037  1.00 41.84  ?  12  ALA A CB  1 
ATOM   50    N  N   . ARG A 1 24  ? 134.247 142.582 97.050  1.00 39.99  ?  13  ARG A N   1 
ATOM   51    C  CA  . ARG A 1 24  ? 133.017 142.977 97.715  1.00 39.99  ?  13  ARG A CA  1 
ATOM   52    C  C   . ARG A 1 24  ? 133.024 144.477 97.954  1.00 39.99  ?  13  ARG A C   1 
ATOM   53    O  O   . ARG A 1 24  ? 134.041 145.131 97.718  1.00 39.99  ?  13  ARG A O   1 
ATOM   54    C  CB  . ARG A 1 24  ? 132.856 142.214 99.025  1.00 39.99  ?  13  ARG A CB  1 
ATOM   55    C  CG  . ARG A 1 24  ? 133.965 142.396 100.016 1.00 39.99  ?  13  ARG A CG  1 
ATOM   56    C  CD  . ARG A 1 24  ? 133.461 141.984 101.347 1.00 39.99  ?  13  ARG A CD  1 
ATOM   57    N  NE  . ARG A 1 24  ? 134.453 142.002 102.407 1.00 39.99  ?  13  ARG A NE  1 
ATOM   58    C  CZ  . ARG A 1 24  ? 134.675 143.038 103.197 1.00 39.99  ?  13  ARG A CZ  1 
ATOM   59    N  NH1 . ARG A 1 24  ? 133.998 144.154 103.029 1.00 39.99  1  13  ARG A NH1 1 
ATOM   60    N  NH2 . ARG A 1 24  ? 135.576 142.957 104.152 1.00 39.99  ?  13  ARG A NH2 1 
ATOM   61    N  N   . PRO A 1 25  ? 131.917 145.067 98.386  1.00 42.30  ?  14  PRO A N   1 
ATOM   62    C  CA  . PRO A 1 25  ? 131.944 146.481 98.754  1.00 42.30  ?  14  PRO A CA  1 
ATOM   63    C  C   . PRO A 1 25  ? 132.696 146.719 100.052 1.00 42.30  ?  14  PRO A C   1 
ATOM   64    O  O   . PRO A 1 25  ? 132.886 145.825 100.874 1.00 42.30  ?  14  PRO A O   1 
ATOM   65    C  CB  . PRO A 1 25  ? 130.464 146.841 98.898  1.00 42.30  ?  14  PRO A CB  1 
ATOM   66    C  CG  . PRO A 1 25  ? 129.761 145.583 98.981  1.00 42.30  ?  14  PRO A CG  1 
ATOM   67    C  CD  . PRO A 1 25  ? 130.540 144.575 98.253  1.00 42.30  ?  14  PRO A CD  1 
ATOM   68    N  N   . VAL A 1 26  ? 133.149 147.952 100.239 1.00 43.41  ?  15  VAL A N   1 
ATOM   69    C  CA  . VAL A 1 26  ? 133.787 148.306 101.493 1.00 43.41  ?  15  VAL A CA  1 
ATOM   70    C  C   . VAL A 1 26  ? 132.636 148.515 102.436 1.00 43.41  ?  15  VAL A C   1 
ATOM   71    O  O   . VAL A 1 26  ? 131.712 149.255 102.125 1.00 43.41  ?  15  VAL A O   1 
ATOM   72    C  CB  . VAL A 1 26  ? 134.654 149.568 101.370 1.00 43.41  ?  15  VAL A CB  1 
ATOM   73    C  CG1 . VAL A 1 26  ? 135.119 150.033 102.739 1.00 43.41  ?  15  VAL A CG1 1 
ATOM   74    C  CG2 . VAL A 1 26  ? 135.836 149.308 100.451 1.00 43.41  ?  15  VAL A CG2 1 
ATOM   75    N  N   . TYR A 1 27  ? 132.668 147.871 103.588 1.00 44.13  ?  16  TYR A N   1 
ATOM   76    C  CA  . TYR A 1 27  ? 131.525 147.938 104.475 1.00 44.13  ?  16  TYR A CA  1 
ATOM   77    C  C   . TYR A 1 27  ? 131.747 148.569 105.812 1.00 44.13  ?  16  TYR A C   1 
ATOM   78    O  O   . TYR A 1 27  ? 132.649 148.182 106.542 1.00 44.13  ?  16  TYR A O   1 
ATOM   79    C  CB  . TYR A 1 27  ? 131.011 146.521 104.745 1.00 44.13  ?  16  TYR A CB  1 
ATOM   80    C  CG  . TYR A 1 27  ? 130.069 145.956 103.718 1.00 44.13  ?  16  TYR A CG  1 
ATOM   81    C  CD1 . TYR A 1 27  ? 128.848 146.560 103.464 1.00 44.13  ?  16  TYR A CD1 1 
ATOM   82    C  CD2 . TYR A 1 27  ? 130.381 144.792 103.033 1.00 44.13  ?  16  TYR A CD2 1 
ATOM   83    C  CE1 . TYR A 1 27  ? 127.975 146.037 102.535 1.00 44.13  ?  16  TYR A CE1 1 
ATOM   84    C  CE2 . TYR A 1 27  ? 129.513 144.260 102.105 1.00 44.13  ?  16  TYR A CE2 1 
ATOM   85    C  CZ  . TYR A 1 27  ? 128.311 144.888 101.861 1.00 44.13  ?  16  TYR A CZ  1 
ATOM   86    O  OH  . TYR A 1 27  ? 127.441 144.367 100.936 1.00 44.13  ?  16  TYR A OH  1 
ATOM   87    N  N   . SER A 1 28  ? 130.922 149.546 106.146 1.00 47.37  ?  17  SER A N   1 
ATOM   88    C  CA  . SER A 1 28  ? 130.957 150.106 107.467 1.00 47.37  ?  17  SER A CA  1 
ATOM   89    C  C   . SER A 1 28  ? 129.946 149.233 108.164 1.00 47.37  ?  17  SER A C   1 
ATOM   90    O  O   . SER A 1 28  ? 129.112 148.622 107.509 1.00 47.37  ?  17  SER A O   1 
ATOM   91    C  CB  . SER A 1 28  ? 130.492 151.536 107.444 1.00 47.37  ?  17  SER A CB  1 
ATOM   92    O  OG  . SER A 1 28  ? 130.540 152.104 108.737 1.00 47.37  ?  17  SER A OG  1 
ATOM   93    N  N   . THR A 1 29  ? 129.998 149.144 109.479 1.00 49.47  ?  18  THR A N   1 
ATOM   94    C  CA  . THR A 1 29  ? 129.093 148.248 110.175 1.00 49.47  ?  18  THR A CA  1 
ATOM   95    C  C   . THR A 1 29  ? 127.637 148.647 109.922 1.00 49.47  ?  18  THR A C   1 
ATOM   96    O  O   . THR A 1 29  ? 126.783 147.786 109.762 1.00 49.47  ?  18  THR A O   1 
ATOM   97    C  CB  . THR A 1 29  ? 129.391 148.195 111.680 1.00 49.47  ?  18  THR A CB  1 
ATOM   98    O  OG1 . THR A 1 29  ? 129.181 149.490 112.253 1.00 49.47  ?  18  THR A OG1 1 
ATOM   99    C  CG2 . THR A 1 29  ? 130.825 147.764 111.916 1.00 49.47  ?  18  THR A CG2 1 
ATOM   100   N  N   . ASN A 1 30  ? 127.349 149.940 109.873 1.00 51.07  ?  19  ASN A N   1 
ATOM   101   C  CA  . ASN A 1 30  ? 125.997 150.404 109.574 1.00 51.07  ?  19  ASN A CA  1 
ATOM   102   C  C   . ASN A 1 30  ? 125.585 150.059 108.156 1.00 51.07  ?  19  ASN A C   1 
ATOM   103   O  O   . ASN A 1 30  ? 124.453 149.657 107.922 1.00 51.07  ?  19  ASN A O   1 
ATOM   104   C  CB  . ASN A 1 30  ? 125.894 151.916 109.786 1.00 51.07  ?  19  ASN A CB  1 
ATOM   105   C  CG  . ASN A 1 30  ? 125.943 152.307 111.248 1.00 51.07  ?  19  ASN A CG  1 
ATOM   106   O  OD1 . ASN A 1 30  ? 125.888 151.457 112.134 1.00 51.07  ?  19  ASN A OD1 1 
ATOM   107   N  ND2 . ASN A 1 30  ? 126.037 153.604 111.506 1.00 51.07  ?  19  ASN A ND2 1 
ATOM   108   N  N   . ALA A 1 31  ? 126.495 150.222 107.208 1.00 51.06  ?  20  ALA A N   1 
ATOM   109   C  CA  . ALA A 1 31  ? 126.211 149.893 105.819 1.00 51.06  ?  20  ALA A CA  1 
ATOM   110   C  C   . ALA A 1 31  ? 125.934 148.417 105.668 1.00 51.06  ?  20  ALA A C   1 
ATOM   111   O  O   . ALA A 1 31  ? 125.086 148.019 104.880 1.00 51.06  ?  20  ALA A O   1 
ATOM   112   C  CB  . ALA A 1 31  ? 127.378 150.288 104.943 1.00 51.06  ?  20  ALA A CB  1 
ATOM   113   N  N   . PHE A 1 32  ? 126.662 147.596 106.408 1.00 49.66  ?  21  PHE A N   1 
ATOM   114   C  CA  . PHE A 1 32  ? 126.425 146.170 106.361 1.00 49.66  ?  21  PHE A CA  1 
ATOM   115   C  C   . PHE A 1 32  ? 125.039 145.849 106.915 1.00 49.66  ?  21  PHE A C   1 
ATOM   116   O  O   . PHE A 1 32  ? 124.310 145.073 106.316 1.00 49.66  ?  21  PHE A O   1 
ATOM   117   C  CB  . PHE A 1 32  ? 127.511 145.407 107.127 1.00 49.66  ?  21  PHE A CB  1 
ATOM   118   C  CG  . PHE A 1 32  ? 127.469 143.924 106.917 1.00 49.66  ?  21  PHE A CG  1 
ATOM   119   C  CD1 . PHE A 1 32  ? 128.147 143.346 105.860 1.00 49.66  ?  21  PHE A CD1 1 
ATOM   120   C  CD2 . PHE A 1 32  ? 126.749 143.108 107.773 1.00 49.66  ?  21  PHE A CD2 1 
ATOM   121   C  CE1 . PHE A 1 32  ? 128.111 141.982 105.659 1.00 49.66  ?  21  PHE A CE1 1 
ATOM   122   C  CE2 . PHE A 1 32  ? 126.707 141.742 107.577 1.00 49.66  ?  21  PHE A CE2 1 
ATOM   123   C  CZ  . PHE A 1 32  ? 127.390 141.178 106.519 1.00 49.66  ?  21  PHE A CZ  1 
ATOM   124   N  N   . GLU A 1 33  ? 124.660 146.450 108.039 1.00 55.41  ?  22  GLU A N   1 
ATOM   125   C  CA  . GLU A 1 33  ? 123.314 146.209 108.544 1.00 55.41  ?  22  GLU A CA  1 
ATOM   126   C  C   . GLU A 1 33  ? 122.250 146.697 107.572 1.00 55.41  ?  22  GLU A C   1 
ATOM   127   O  O   . GLU A 1 33  ? 121.172 146.104 107.489 1.00 55.41  ?  22  GLU A O   1 
ATOM   128   C  CB  . GLU A 1 33  ? 123.104 146.885 109.897 1.00 55.41  ?  22  GLU A CB  1 
ATOM   129   C  CG  . GLU A 1 33  ? 124.140 146.587 110.965 1.00 55.41  ?  22  GLU A CG  1 
ATOM   130   C  CD  . GLU A 1 33  ? 124.624 145.155 110.963 1.00 55.41  ?  22  GLU A CD  1 
ATOM   131   O  OE1 . GLU A 1 33  ? 125.847 144.939 110.832 1.00 55.41  ?  22  GLU A OE1 1 
ATOM   132   O  OE2 . GLU A 1 33  ? 123.777 144.244 111.092 1.00 55.41  -1 22  GLU A OE2 1 
ATOM   133   N  N   . GLU A 1 34  ? 122.521 147.781 106.850 1.00 56.84  ?  23  GLU A N   1 
ATOM   134   C  CA  . GLU A 1 34  ? 121.549 148.283 105.889 1.00 56.84  ?  23  GLU A CA  1 
ATOM   135   C  C   . GLU A 1 34  ? 121.376 147.324 104.725 1.00 56.84  ?  23  GLU A C   1 
ATOM   136   O  O   . GLU A 1 34  ? 120.273 147.185 104.189 1.00 56.84  ?  23  GLU A O   1 
ATOM   137   C  CB  . GLU A 1 34  ? 121.970 149.656 105.374 1.00 56.84  ?  23  GLU A CB  1 
ATOM   138   C  CG  . GLU A 1 34  ? 121.844 150.774 106.388 1.00 56.84  ?  23  GLU A CG  1 
ATOM   139   C  CD  . GLU A 1 34  ? 122.678 151.987 106.024 1.00 56.84  ?  23  GLU A CD  1 
ATOM   140   O  OE1 . GLU A 1 34  ? 123.111 152.087 104.859 1.00 56.84  ?  23  GLU A OE1 1 
ATOM   141   O  OE2 . GLU A 1 34  ? 122.916 152.838 106.906 1.00 56.84  -1 23  GLU A OE2 1 
ATOM   142   N  N   . ASN A 1 35  ? 122.452 146.663 104.309 1.00 55.04  ?  24  ASN A N   1 
ATOM   143   C  CA  . ASN A 1 35  ? 122.371 145.843 103.108 1.00 55.04  ?  24  ASN A CA  1 
ATOM   144   C  C   . ASN A 1 35  ? 121.984 144.405 103.419 1.00 55.04  ?  24  ASN A C   1 
ATOM   145   O  O   . ASN A 1 35  ? 121.588 143.661 102.519 1.00 55.04  ?  24  ASN A O   1 
ATOM   146   C  CB  . ASN A 1 35  ? 123.698 145.884 102.360 1.00 55.04  ?  24  ASN A CB  1 
ATOM   147   C  CG  . ASN A 1 35  ? 123.873 147.158 101.577 1.00 55.04  ?  24  ASN A CG  1 
ATOM   148   O  OD1 . ASN A 1 35  ? 123.435 147.255 100.434 1.00 55.04  ?  24  ASN A OD1 1 
ATOM   149   N  ND2 . ASN A 1 35  ? 124.511 148.149 102.186 1.00 55.04  ?  24  ASN A ND2 1 
ATOM   150   N  N   . HIS A 1 36  ? 122.102 143.989 104.669 1.00 54.62  ?  25  HIS A N   1 
ATOM   151   C  CA  . HIS A 1 36  ? 121.819 142.617 105.051 1.00 54.62  ?  25  HIS A CA  1 
ATOM   152   C  C   . HIS A 1 36  ? 120.789 142.595 106.160 1.00 54.62  ?  25  HIS A C   1 
ATOM   153   O  O   . HIS A 1 36  ? 121.049 143.057 107.272 1.00 54.62  ?  25  HIS A O   1 
ATOM   154   C  CB  . HIS A 1 36  ? 123.091 141.903 105.495 1.00 54.62  ?  25  HIS A CB  1 
ATOM   155   C  CG  . HIS A 1 36  ? 124.108 141.784 104.411 1.00 54.62  ?  25  HIS A CG  1 
ATOM   156   N  ND1 . HIS A 1 36  ? 125.009 142.783 104.126 1.00 54.62  ?  25  HIS A ND1 1 
ATOM   157   C  CD2 . HIS A 1 36  ? 124.335 140.804 103.510 1.00 54.62  ?  25  HIS A CD2 1 
ATOM   158   C  CE1 . HIS A 1 36  ? 125.763 142.414 103.110 1.00 54.62  ?  25  HIS A CE1 1 
ATOM   159   N  NE2 . HIS A 1 36  ? 125.375 141.216 102.717 1.00 54.62  ?  25  HIS A NE2 1 
ATOM   160   N  N   . LYS A 1 37  ? 119.618 142.052 105.853 1.00 64.16  ?  26  LYS A N   1 
ATOM   161   C  CA  . LYS A 1 37  ? 118.526 142.108 106.799 1.00 64.16  ?  26  LYS A CA  1 
ATOM   162   C  C   . LYS A 1 37  ? 118.838 141.243 108.015 1.00 64.16  ?  26  LYS A C   1 
ATOM   163   O  O   . LYS A 1 37  ? 119.341 140.126 107.911 1.00 64.16  ?  26  LYS A O   1 
ATOM   164   C  CB  . LYS A 1 37  ? 117.226 141.664 106.140 1.00 64.16  ?  26  LYS A CB  1 
ATOM   165   C  CG  . LYS A 1 37  ? 115.999 142.164 106.867 1.00 64.16  ?  26  LYS A CG  1 
ATOM   166   C  CD  . LYS A 1 37  ? 114.728 141.551 106.321 1.00 64.16  ?  26  LYS A CD  1 
ATOM   167   C  CE  . LYS A 1 37  ? 113.790 141.180 107.453 1.00 64.16  ?  26  LYS A CE  1 
ATOM   168   N  NZ  . LYS A 1 37  ? 113.744 142.242 108.500 1.00 64.16  1  26  LYS A NZ  1 
ATOM   169   N  N   . LYS A 1 38  ? 118.546 141.766 109.197 1.00 64.44  ?  27  LYS A N   1 
ATOM   170   C  CA  . LYS A 1 38  ? 118.783 141.007 110.415 1.00 64.44  ?  27  LYS A CA  1 
ATOM   171   C  C   . LYS A 1 38  ? 117.637 140.070 110.688 1.00 64.44  ?  27  LYS A C   1 
ATOM   172   O  O   . LYS A 1 38  ? 116.669 140.026 109.936 1.00 64.44  ?  27  LYS A O   1 
ATOM   173   C  CB  . LYS A 1 38  ? 118.947 141.947 111.600 1.00 64.44  ?  27  LYS A CB  1 
ATOM   174   C  CG  . LYS A 1 38  ? 120.340 142.527 111.773 1.00 64.44  ?  27  LYS A CG  1 
ATOM   175   C  CD  . LYS A 1 38  ? 121.209 141.605 112.610 1.00 64.44  ?  27  LYS A CD  1 
ATOM   176   C  CE  . LYS A 1 38  ? 122.400 142.349 113.188 1.00 64.44  ?  27  LYS A CE  1 
ATOM   177   N  NZ  . LYS A 1 38  ? 123.151 141.517 114.168 1.00 64.44  1  27  LYS A NZ  1 
ATOM   178   N  N   . THR A 1 39  ? 117.740 139.315 111.768 1.00 68.73  ?  28  THR A N   1 
ATOM   179   C  CA  . THR A 1 39  ? 116.679 138.402 112.134 1.00 68.73  ?  28  THR A CA  1 
ATOM   180   C  C   . THR A 1 39  ? 115.998 138.950 113.370 1.00 68.73  ?  28  THR A C   1 
ATOM   181   O  O   . THR A 1 39  ? 116.577 139.758 114.094 1.00 68.73  ?  28  THR A O   1 
ATOM   182   C  CB  . THR A 1 39  ? 117.217 136.991 112.405 1.00 68.73  ?  28  THR A CB  1 
ATOM   183   O  OG1 . THR A 1 39  ? 118.223 137.050 113.423 1.00 68.73  ?  28  THR A OG1 1 
ATOM   184   C  CG2 . THR A 1 39  ? 117.814 136.402 111.140 1.00 68.73  ?  28  THR A CG2 1 
ATOM   185   N  N   . GLY A 1 40  ? 114.766 138.529 113.612 1.00 80.26  ?  29  GLY A N   1 
ATOM   186   C  CA  . GLY A 1 40  ? 114.058 138.979 114.791 1.00 80.26  ?  29  GLY A CA  1 
ATOM   187   C  C   . GLY A 1 40  ? 114.767 138.547 116.053 1.00 80.26  ?  29  GLY A C   1 
ATOM   188   O  O   . GLY A 1 40  ? 115.215 137.404 116.159 1.00 80.26  ?  29  GLY A O   1 
ATOM   189   N  N   . ARG A 1 41  ? 114.881 139.460 117.009 1.00 89.08  ?  30  ARG A N   1 
ATOM   190   C  CA  . ARG A 1 41  ? 115.536 139.140 118.268 1.00 89.08  ?  30  ARG A CA  1 
ATOM   191   C  C   . ARG A 1 41  ? 114.599 139.338 119.444 1.00 89.08  ?  30  ARG A C   1 
ATOM   192   O  O   . ARG A 1 41  ? 113.705 140.181 119.395 1.00 89.08  ?  30  ARG A O   1 
ATOM   193   C  CB  . ARG A 1 41  ? 116.770 140.015 118.459 1.00 89.08  ?  30  ARG A CB  1 
ATOM   194   N  N   . HIS A 1 42  ? 114.795 138.565 120.505 1.00 107.08 ?  31  HIS A N   1 
ATOM   195   C  CA  . HIS A 1 42  ? 113.986 138.743 121.707 1.00 107.08 ?  31  HIS A CA  1 
ATOM   196   C  C   . HIS A 1 42  ? 114.857 139.153 122.882 1.00 107.08 ?  31  HIS A C   1 
ATOM   197   O  O   . HIS A 1 42  ? 115.972 138.654 123.037 1.00 107.08 ?  31  HIS A O   1 
ATOM   198   C  CB  . HIS A 1 42  ? 113.215 137.465 122.040 1.00 107.08 ?  31  HIS A CB  1 
ATOM   199   C  CG  . HIS A 1 42  ? 114.073 136.376 122.603 1.00 107.08 ?  31  HIS A CG  1 
ATOM   200   N  ND1 . HIS A 1 42  ? 114.868 135.571 121.816 1.00 107.08 ?  31  HIS A ND1 1 
ATOM   201   C  CD2 . HIS A 1 42  ? 114.263 135.962 123.879 1.00 107.08 ?  31  HIS A CD2 1 
ATOM   202   C  CE1 . HIS A 1 42  ? 115.510 134.708 122.582 1.00 107.08 ?  31  HIS A CE1 1 
ATOM   203   N  NE2 . HIS A 1 42  ? 115.161 134.924 123.837 1.00 107.08 ?  31  HIS A NE2 1 
ATOM   204   N  N   . HIS A 1 43  ? 114.333 140.021 123.741 1.00 116.25 ?  32  HIS A N   1 
ATOM   205   C  CA  . HIS A 1 43  ? 115.083 140.476 124.909 1.00 116.25 ?  32  HIS A CA  1 
ATOM   206   C  C   . HIS A 1 43  ? 115.216 139.406 125.990 1.00 116.25 ?  32  HIS A C   1 
ATOM   207   O  O   . HIS A 1 43  ? 116.077 139.513 126.863 1.00 116.25 ?  32  HIS A O   1 
ATOM   208   C  CB  . HIS A 1 43  ? 114.410 141.718 125.497 1.00 116.25 ?  32  HIS A CB  1 
ATOM   209   C  CG  . HIS A 1 43  ? 115.009 142.177 126.789 1.00 116.25 ?  32  HIS A CG  1 
ATOM   210   N  ND1 . HIS A 1 43  ? 116.206 142.857 126.853 1.00 116.25 ?  32  HIS A ND1 1 
ATOM   211   C  CD2 . HIS A 1 43  ? 114.576 142.058 128.066 1.00 116.25 ?  32  HIS A CD2 1 
ATOM   212   C  CE1 . HIS A 1 43  ? 116.485 143.134 128.114 1.00 116.25 ?  32  HIS A CE1 1 
ATOM   213   N  NE2 . HIS A 1 43  ? 115.513 142.660 128.870 1.00 116.25 ?  32  HIS A NE2 1 
ATOM   214   N  N   . LYS A 1 44  ? 114.372 138.380 125.942 1.00 122.11 ?  33  LYS A N   1 
ATOM   215   C  CA  . LYS A 1 44  ? 114.395 137.350 126.976 1.00 122.11 ?  33  LYS A CA  1 
ATOM   216   C  C   . LYS A 1 44  ? 114.290 138.020 128.332 1.00 122.11 ?  33  LYS A C   1 
ATOM   217   O  O   . LYS A 1 44  ? 115.075 137.737 129.236 1.00 122.11 ?  33  LYS A O   1 
ATOM   218   C  CB  . LYS A 1 44  ? 115.662 136.503 126.878 1.00 122.11 ?  33  LYS A CB  1 
ATOM   219   N  N   . THR A 1 45  ? 113.321 138.916 128.473 1.00 132.28 ?  34  THR A N   1 
ATOM   220   C  CA  . THR A 1 45  ? 113.163 139.657 129.722 1.00 132.28 ?  34  THR A CA  1 
ATOM   221   C  C   . THR A 1 45  ? 113.306 138.792 130.961 1.00 132.28 ?  34  THR A C   1 
ATOM   222   O  O   . THR A 1 45  ? 112.833 137.660 130.995 1.00 132.28 ?  34  THR A O   1 
ATOM   223   C  CB  . THR A 1 45  ? 111.792 140.360 129.771 1.00 132.28 ?  34  THR A CB  1 
ATOM   224   O  OG1 . THR A 1 45  ? 111.639 141.190 128.613 1.00 132.28 ?  34  THR A OG1 1 
ATOM   225   C  CG2 . THR A 1 45  ? 111.676 141.219 131.016 1.00 132.28 ?  34  THR A CG2 1 
ATOM   226   N  N   . PHE A 1 46  ? 113.964 139.321 131.984 1.00 134.86 ?  35  PHE A N   1 
ATOM   227   C  CA  . PHE A 1 46  ? 114.092 138.590 133.232 1.00 134.86 ?  35  PHE A CA  1 
ATOM   228   C  C   . PHE A 1 46  ? 112.714 138.167 133.692 1.00 134.86 ?  35  PHE A C   1 
ATOM   229   O  O   . PHE A 1 46  ? 112.550 137.094 134.268 1.00 134.86 ?  35  PHE A O   1 
ATOM   230   C  CB  . PHE A 1 46  ? 114.762 139.464 134.286 1.00 134.86 ?  35  PHE A CB  1 
ATOM   231   C  CG  . PHE A 1 46  ? 115.043 138.752 135.574 1.00 134.86 ?  35  PHE A CG  1 
ATOM   232   C  CD1 . PHE A 1 46  ? 116.005 137.760 135.635 1.00 134.86 ?  35  PHE A CD1 1 
ATOM   233   C  CD2 . PHE A 1 46  ? 114.355 139.085 136.728 1.00 134.86 ?  35  PHE A CD2 1 
ATOM   234   C  CE1 . PHE A 1 46  ? 116.271 137.105 136.821 1.00 134.86 ?  35  PHE A CE1 1 
ATOM   235   C  CE2 . PHE A 1 46  ? 114.616 138.436 137.918 1.00 134.86 ?  35  PHE A CE2 1 
ATOM   236   C  CZ  . PHE A 1 46  ? 115.575 137.444 137.965 1.00 134.86 ?  35  PHE A CZ  1 
ATOM   237   N  N   . LEU A 1 47  ? 111.716 138.999 133.419 1.00 135.66 ?  36  LEU A N   1 
ATOM   238   C  CA  . LEU A 1 47  ? 110.350 138.642 133.766 1.00 135.66 ?  36  LEU A CA  1 
ATOM   239   C  C   . LEU A 1 47  ? 109.984 137.367 133.041 1.00 135.66 ?  36  LEU A C   1 
ATOM   240   O  O   . LEU A 1 47  ? 109.226 136.554 133.557 1.00 135.66 ?  36  LEU A O   1 
ATOM   241   C  CB  . LEU A 1 47  ? 109.387 139.764 133.388 1.00 135.66 ?  36  LEU A CB  1 
ATOM   242   C  CG  . LEU A 1 47  ? 107.924 139.594 133.805 1.00 135.66 ?  36  LEU A CG  1 
ATOM   243   C  CD1 . LEU A 1 47  ? 107.136 138.753 132.813 1.00 135.66 ?  36  LEU A CD1 1 
ATOM   244   C  CD2 . LEU A 1 47  ? 107.825 139.032 135.215 1.00 135.66 ?  36  LEU A CD2 1 
ATOM   245   N  N   . ASP A 1 48  ? 110.510 137.192 131.835 1.00 135.83 ?  37  ASP A N   1 
ATOM   246   C  CA  . ASP A 1 48  ? 110.260 135.968 131.092 1.00 135.83 ?  37  ASP A CA  1 
ATOM   247   C  C   . ASP A 1 48  ? 110.900 134.818 131.834 1.00 135.83 ?  37  ASP A C   1 
ATOM   248   O  O   . ASP A 1 48  ? 110.342 133.726 131.897 1.00 135.83 ?  37  ASP A O   1 
ATOM   249   C  CB  . ASP A 1 48  ? 110.831 136.063 129.682 1.00 135.83 ?  37  ASP A CB  1 
ATOM   250   C  CG  . ASP A 1 48  ? 110.420 137.336 128.971 1.00 135.83 ?  37  ASP A CG  1 
ATOM   251   O  OD1 . ASP A 1 48  ? 109.554 138.064 129.502 1.00 135.83 ?  37  ASP A OD1 1 
ATOM   252   O  OD2 . ASP A 1 48  ? 110.963 137.609 127.881 1.00 135.83 -1 37  ASP A OD2 1 
ATOM   253   N  N   . HIS A 1 49  ? 112.083 135.053 132.389 1.00 135.29 ?  38  HIS A N   1 
ATOM   254   C  CA  . HIS A 1 49  ? 112.734 134.019 133.173 1.00 135.29 ?  38  HIS A CA  1 
ATOM   255   C  C   . HIS A 1 49  ? 111.862 133.717 134.368 1.00 135.29 ?  38  HIS A C   1 
ATOM   256   O  O   . HIS A 1 49  ? 111.671 132.559 134.731 1.00 135.29 ?  38  HIS A O   1 
ATOM   257   C  CB  . HIS A 1 49  ? 114.116 134.475 133.623 1.00 135.29 ?  38  HIS A CB  1 
ATOM   258   C  CG  . HIS A 1 49  ? 115.037 134.805 132.491 1.00 135.29 ?  38  HIS A CG  1 
ATOM   259   N  ND1 . HIS A 1 49  ? 115.883 133.876 131.925 1.00 135.29 ?  38  HIS A ND1 1 
ATOM   260   C  CD2 . HIS A 1 49  ? 115.240 135.959 131.814 1.00 135.29 ?  38  HIS A CD2 1 
ATOM   261   C  CE1 . HIS A 1 49  ? 116.571 134.445 130.951 1.00 135.29 ?  38  HIS A CE1 1 
ATOM   262   N  NE2 . HIS A 1 49  ? 116.199 135.709 130.863 1.00 135.29 ?  38  HIS A NE2 1 
ATOM   263   N  N   . LEU A 1 50  ? 111.319 134.758 134.983 1.00 134.81 ?  39  LEU A N   1 
ATOM   264   C  CA  . LEU A 1 50  ? 110.425 134.556 136.109 1.00 134.81 ?  39  LEU A CA  1 
ATOM   265   C  C   . LEU A 1 50  ? 109.193 133.825 135.623 1.00 134.81 ?  39  LEU A C   1 
ATOM   266   O  O   . LEU A 1 50  ? 108.622 133.005 136.340 1.00 134.81 ?  39  LEU A O   1 
ATOM   267   C  CB  . LEU A 1 50  ? 110.046 135.893 136.734 1.00 134.81 ?  39  LEU A CB  1 
ATOM   268   C  CG  . LEU A 1 50  ? 111.243 136.779 137.076 1.00 134.81 ?  39  LEU A CG  1 
ATOM   269   C  CD1 . LEU A 1 50  ? 110.794 138.099 137.681 1.00 134.81 ?  39  LEU A CD1 1 
ATOM   270   C  CD2 . LEU A 1 50  ? 112.190 136.044 138.011 1.00 134.81 ?  39  LEU A CD2 1 
ATOM   271   N  N   . LYS A 1 51  ? 108.778 134.122 134.400 1.00 134.23 ?  40  LYS A N   1 
ATOM   272   C  CA  . LYS A 1 51  ? 107.601 133.480 133.839 1.00 134.23 ?  40  LYS A CA  1 
ATOM   273   C  C   . LYS A 1 51  ? 107.831 131.992 133.634 1.00 134.23 ?  40  LYS A C   1 
ATOM   274   O  O   . LYS A 1 51  ? 106.975 131.174 133.970 1.00 134.23 ?  40  LYS A O   1 
ATOM   275   C  CB  . LYS A 1 51  ? 107.217 134.141 132.514 1.00 134.23 ?  40  LYS A CB  1 
ATOM   276   C  CG  . LYS A 1 51  ? 105.951 133.591 131.874 1.00 134.23 ?  40  LYS A CG  1 
ATOM   277   C  CD  . LYS A 1 51  ? 105.589 134.315 130.585 1.00 134.23 ?  40  LYS A CD  1 
ATOM   278   C  CE  . LYS A 1 51  ? 104.337 133.750 129.932 1.00 134.23 ?  40  LYS A CE  1 
ATOM   279   N  NZ  . LYS A 1 51  ? 103.994 134.466 128.673 1.00 134.23 1  40  LYS A NZ  1 
ATOM   280   N  N   . VAL A 1 52  ? 108.988 131.637 133.084 1.00 132.91 ?  41  VAL A N   1 
ATOM   281   C  CA  . VAL A 1 52  ? 109.280 130.231 132.827 1.00 132.91 ?  41  VAL A CA  1 
ATOM   282   C  C   . VAL A 1 52  ? 109.400 129.465 134.138 1.00 132.91 ?  41  VAL A C   1 
ATOM   283   O  O   . VAL A 1 52  ? 108.994 128.307 134.224 1.00 132.91 ?  41  VAL A O   1 
ATOM   284   C  CB  . VAL A 1 52  ? 110.558 130.040 131.983 1.00 132.91 ?  41  VAL A CB  1 
ATOM   285   C  CG1 . VAL A 1 52  ? 110.469 130.849 130.698 1.00 132.91 ?  41  VAL A CG1 1 
ATOM   286   C  CG2 . VAL A 1 52  ? 111.801 130.415 132.771 1.00 132.91 ?  41  VAL A CG2 1 
ATOM   287   N  N   . CYS A 1 53  ? 109.948 130.111 135.160 1.00 132.79 ?  42  CYS A N   1 
ATOM   288   C  CA  . CYS A 1 53  ? 110.076 129.462 136.456 1.00 132.79 ?  42  CYS A CA  1 
ATOM   289   C  C   . CYS A 1 53  ? 108.701 129.075 136.965 1.00 132.79 ?  42  CYS A C   1 
ATOM   290   O  O   . CYS A 1 53  ? 108.544 128.049 137.623 1.00 132.79 ?  42  CYS A O   1 
ATOM   291   C  CB  . CYS A 1 53  ? 110.785 130.377 137.452 1.00 132.79 ?  42  CYS A CB  1 
ATOM   292   S  SG  . CYS A 1 53  ? 112.522 130.681 137.057 1.00 132.79 ?  42  CYS A SG  1 
ATOM   293   N  N   . CYS A 1 54  ? 107.702 129.892 136.660 1.00 129.42 ?  43  CYS A N   1 
ATOM   294   C  CA  . CYS A 1 54  ? 106.345 129.575 137.066 1.00 129.42 ?  43  CYS A CA  1 
ATOM   295   C  C   . CYS A 1 54  ? 105.734 128.608 136.071 1.00 129.42 ?  43  CYS A C   1 
ATOM   296   O  O   . CYS A 1 54  ? 104.743 128.921 135.415 1.00 129.42 ?  43  CYS A O   1 
ATOM   297   C  CB  . CYS A 1 54  ? 105.501 130.844 137.160 1.00 129.42 ?  43  CYS A CB  1 
ATOM   298   S  SG  . CYS A 1 54  ? 103.854 130.592 137.861 1.00 129.42 ?  43  CYS A SG  1 
ATOM   299   N  N   . SER A 1 55  ? 106.273 127.395 136.004 1.00 123.06 ?  44  SER A N   1 
ATOM   300   C  CA  . SER A 1 55  ? 105.719 126.380 135.107 1.00 123.06 ?  44  SER A CA  1 
ATOM   301   C  C   . SER A 1 55  ? 104.721 125.463 135.804 1.00 123.06 ?  44  SER A C   1 
ATOM   302   O  O   . SER A 1 55  ? 103.532 125.496 135.491 1.00 123.06 ?  44  SER A O   1 
ATOM   303   C  CB  . SER A 1 55  ? 106.843 125.543 134.498 1.00 123.06 ?  44  SER A CB  1 
ATOM   304   O  OG  . SER A 1 55  ? 106.320 124.443 133.774 1.00 123.06 ?  44  SER A OG  1 
ATOM   305   N  N   . CYS A 1 56  ? 105.201 124.634 136.727 1.00 118.59 ?  45  CYS A N   1 
ATOM   306   C  CA  . CYS A 1 56  ? 104.334 123.706 137.466 1.00 118.59 ?  45  CYS A CA  1 
ATOM   307   C  C   . CYS A 1 56  ? 103.801 122.579 136.586 1.00 118.59 ?  45  CYS A C   1 
ATOM   308   O  O   . CYS A 1 56  ? 102.832 121.911 136.945 1.00 118.59 ?  45  CYS A O   1 
ATOM   309   C  CB  . CYS A 1 56  ? 103.179 124.448 138.149 1.00 118.59 ?  45  CYS A CB  1 
ATOM   310   S  SG  . CYS A 1 56  ? 102.254 123.465 139.354 1.00 118.59 ?  45  CYS A SG  1 
ATOM   311   N  N   . SER A 1 57  ? 104.428 122.355 135.438 1.00 111.75 ?  46  SER A N   1 
ATOM   312   C  CA  . SER A 1 57  ? 104.017 121.236 134.606 1.00 111.75 ?  46  SER A CA  1 
ATOM   313   C  C   . SER A 1 57  ? 104.335 119.948 135.349 1.00 111.75 ?  46  SER A C   1 
ATOM   314   O  O   . SER A 1 57  ? 105.399 119.824 135.953 1.00 111.75 ?  46  SER A O   1 
ATOM   315   C  CB  . SER A 1 57  ? 104.719 121.272 133.252 1.00 111.75 ?  46  SER A CB  1 
ATOM   316   O  OG  . SER A 1 57  ? 106.123 121.200 133.400 1.00 111.75 ?  46  SER A OG  1 
ATOM   317   N  N   . PRO A 1 58  ? 103.415 118.977 135.313 1.00 108.81 ?  47  PRO A N   1 
ATOM   318   C  CA  . PRO A 1 58  ? 103.644 117.756 136.094 1.00 108.81 ?  47  PRO A CA  1 
ATOM   319   C  C   . PRO A 1 58  ? 104.967 117.125 135.715 1.00 108.81 ?  47  PRO A C   1 
ATOM   320   O  O   . PRO A 1 58  ? 105.651 116.578 136.575 1.00 108.81 ?  47  PRO A O   1 
ATOM   321   C  CB  . PRO A 1 58  ? 102.485 116.850 135.679 1.00 108.81 ?  47  PRO A CB  1 
ATOM   322   C  CG  . PRO A 1 58  ? 101.425 117.785 135.194 1.00 108.81 ?  47  PRO A CG  1 
ATOM   323   C  CD  . PRO A 1 58  ? 102.152 118.934 134.560 1.00 108.81 ?  47  PRO A CD  1 
ATOM   324   N  N   . GLN A 1 59  ? 105.329 117.200 134.445 1.00 106.24 ?  48  GLN A N   1 
ATOM   325   C  CA  . GLN A 1 59  ? 106.611 116.676 134.011 1.00 106.24 ?  48  GLN A CA  1 
ATOM   326   C  C   . GLN A 1 59  ? 107.745 117.434 134.681 1.00 106.24 ?  48  GLN A C   1 
ATOM   327   O  O   . GLN A 1 59  ? 108.754 116.843 135.059 1.00 106.24 ?  48  GLN A O   1 
ATOM   328   C  CB  . GLN A 1 59  ? 106.734 116.774 132.493 1.00 106.24 ?  48  GLN A CB  1 
ATOM   329   C  CG  . GLN A 1 59  ? 106.437 118.159 131.944 1.00 106.24 ?  48  GLN A CG  1 
ATOM   330   C  CD  . GLN A 1 59  ? 106.638 118.247 130.445 1.00 106.24 ?  48  GLN A CD  1 
ATOM   331   O  OE1 . GLN A 1 59  ? 106.414 119.293 129.837 1.00 106.24 ?  48  GLN A OE1 1 
ATOM   332   N  NE2 . GLN A 1 59  ? 107.065 117.144 129.840 1.00 106.24 ?  48  GLN A NE2 1 
ATOM   333   N  N   . LYS A 1 60  ? 107.587 118.744 134.832 1.00 104.73 ?  49  LYS A N   1 
ATOM   334   C  CA  . LYS A 1 60  ? 108.612 119.529 135.504 1.00 104.73 ?  49  LYS A CA  1 
ATOM   335   C  C   . LYS A 1 60  ? 108.690 119.131 136.967 1.00 104.73 ?  49  LYS A C   1 
ATOM   336   O  O   . LYS A 1 60  ? 109.777 118.970 137.512 1.00 104.73 ?  49  LYS A O   1 
ATOM   337   C  CB  . LYS A 1 60  ? 108.349 121.028 135.385 1.00 104.73 ?  49  LYS A CB  1 
ATOM   338   C  CG  . LYS A 1 60  ? 109.526 121.877 135.828 1.00 104.73 ?  49  LYS A CG  1 
ATOM   339   C  CD  . LYS A 1 60  ? 109.136 123.331 136.025 1.00 104.73 ?  49  LYS A CD  1 
ATOM   340   C  CE  . LYS A 1 60  ? 108.206 123.491 137.215 1.00 104.73 ?  49  LYS A CE  1 
ATOM   341   N  NZ  . LYS A 1 60  ? 107.985 124.926 137.544 1.00 104.73 1  49  LYS A NZ  1 
ATOM   342   N  N   . ALA A 1 61  ? 107.542 118.960 137.608 1.00 98.22  ?  50  ALA A N   1 
ATOM   343   C  CA  . ALA A 1 61  ? 107.544 118.529 138.995 1.00 98.22  ?  50  ALA A CA  1 
ATOM   344   C  C   . ALA A 1 61  ? 108.250 117.195 139.100 1.00 98.22  ?  50  ALA A C   1 
ATOM   345   O  O   . ALA A 1 61  ? 109.060 116.981 140.000 1.00 98.22  ?  50  ALA A O   1 
ATOM   346   C  CB  . ALA A 1 61  ? 106.129 118.423 139.528 1.00 98.22  ?  50  ALA A CB  1 
ATOM   347   N  N   . LYS A 1 62  ? 107.961 116.299 138.167 1.00 94.69  ?  51  LYS A N   1 
ATOM   348   C  CA  . LYS A 1 62  ? 108.585 114.991 138.186 1.00 94.69  ?  51  LYS A CA  1 
ATOM   349   C  C   . LYS A 1 62  ? 110.088 115.118 138.088 1.00 94.69  ?  51  LYS A C   1 
ATOM   350   O  O   . LYS A 1 62  ? 110.817 114.519 138.872 1.00 94.69  ?  51  LYS A O   1 
ATOM   351   C  CB  . LYS A 1 62  ? 108.078 114.140 137.031 1.00 94.69  ?  51  LYS A CB  1 
ATOM   352   C  CG  . LYS A 1 62  ? 108.769 112.792 136.927 1.00 94.69  ?  51  LYS A CG  1 
ATOM   353   C  CD  . LYS A 1 62  ? 108.372 112.058 135.658 1.00 94.69  ?  51  LYS A CD  1 
ATOM   354   C  CE  . LYS A 1 62  ? 109.105 110.731 135.541 1.00 94.69  ?  51  LYS A CE  1 
ATOM   355   N  NZ  . LYS A 1 62  ? 108.768 110.021 134.277 1.00 94.69  1  51  LYS A NZ  1 
ATOM   356   N  N   . ARG A 1 63  ? 110.562 115.905 137.133 1.00 93.68  ?  52  ARG A N   1 
ATOM   357   C  CA  . ARG A 1 63  ? 111.998 116.017 136.943 1.00 93.68  ?  52  ARG A CA  1 
ATOM   358   C  C   . ARG A 1 63  ? 112.643 116.628 138.176 1.00 93.68  ?  52  ARG A C   1 
ATOM   359   O  O   . ARG A 1 63  ? 113.726 116.218 138.577 1.00 93.68  ?  52  ARG A O   1 
ATOM   360   C  CB  . ARG A 1 63  ? 112.338 116.825 135.690 1.00 93.68  ?  52  ARG A CB  1 
ATOM   361   C  CG  . ARG A 1 63  ? 111.989 118.298 135.771 1.00 93.68  ?  52  ARG A CG  1 
ATOM   362   C  CD  . ARG A 1 63  ? 112.498 119.054 134.558 1.00 93.68  ?  52  ARG A CD  1 
ATOM   363   N  NE  . ARG A 1 63  ? 112.275 120.490 134.687 1.00 93.68  ?  52  ARG A NE  1 
ATOM   364   C  CZ  . ARG A 1 63  ? 113.099 121.317 135.321 1.00 93.68  ?  52  ARG A CZ  1 
ATOM   365   N  NH1 . ARG A 1 63  ? 112.819 122.611 135.391 1.00 93.68  1  52  ARG A NH1 1 
ATOM   366   N  NH2 . ARG A 1 63  ? 114.202 120.850 135.888 1.00 93.68  ?  52  ARG A NH2 1 
ATOM   367   N  N   . ILE A 1 64  ? 111.973 117.597 138.789 1.00 87.83  ?  53  ILE A N   1 
ATOM   368   C  CA  . ILE A 1 64  ? 112.519 118.241 139.973 1.00 87.83  ?  53  ILE A CA  1 
ATOM   369   C  C   . ILE A 1 64  ? 112.685 117.260 141.124 1.00 87.83  ?  53  ILE A C   1 
ATOM   370   O  O   . ILE A 1 64  ? 113.761 117.156 141.706 1.00 87.83  ?  53  ILE A O   1 
ATOM   371   C  CB  . ILE A 1 64  ? 111.627 119.398 140.449 1.00 87.83  ?  53  ILE A CB  1 
ATOM   372   C  CG1 . ILE A 1 64  ? 111.572 120.496 139.387 1.00 87.83  ?  53  ILE A CG1 1 
ATOM   373   C  CG2 . ILE A 1 64  ? 112.140 119.959 141.764 1.00 87.83  ?  53  ILE A CG2 1 
ATOM   374   C  CD1 . ILE A 1 64  ? 112.927 121.059 139.024 1.00 87.83  ?  53  ILE A CD1 1 
ATOM   375   N  N   . VAL A 1 65  ? 111.627 116.531 141.450 1.00 83.22  ?  54  VAL A N   1 
ATOM   376   C  CA  . VAL A 1 65  ? 111.697 115.606 142.567 1.00 83.22  ?  54  VAL A CA  1 
ATOM   377   C  C   . VAL A 1 65  ? 112.719 114.526 142.260 1.00 83.22  ?  54  VAL A C   1 
ATOM   378   O  O   . VAL A 1 65  ? 113.489 114.132 143.128 1.00 83.22  ?  54  VAL A O   1 
ATOM   379   C  CB  . VAL A 1 65  ? 110.327 114.984 142.889 1.00 83.22  ?  54  VAL A CB  1 
ATOM   380   C  CG1 . VAL A 1 65  ? 109.384 116.045 143.433 1.00 83.22  ?  54  VAL A CG1 1 
ATOM   381   C  CG2 . VAL A 1 65  ? 109.734 114.310 141.666 1.00 83.22  ?  54  VAL A CG2 1 
ATOM   382   N  N   . LEU A 1 66  ? 112.738 114.056 141.024 1.00 79.82  ?  55  LEU A N   1 
ATOM   383   C  CA  . LEU A 1 66  ? 113.712 113.059 140.642 1.00 79.82  ?  55  LEU A CA  1 
ATOM   384   C  C   . LEU A 1 66  ? 115.092 113.671 140.702 1.00 79.82  ?  55  LEU A C   1 
ATOM   385   O  O   . LEU A 1 66  ? 116.069 112.977 140.977 1.00 79.82  ?  55  LEU A O   1 
ATOM   386   C  CB  . LEU A 1 66  ? 113.425 112.536 139.241 1.00 79.82  ?  55  LEU A CB  1 
ATOM   387   C  CG  . LEU A 1 66  ? 112.474 111.345 139.125 1.00 79.82  ?  55  LEU A CG  1 
ATOM   388   C  CD1 . LEU A 1 66  ? 111.187 111.570 139.901 1.00 79.82  ?  55  LEU A CD1 1 
ATOM   389   C  CD2 . LEU A 1 66  ? 112.181 111.039 137.665 1.00 79.82  ?  55  LEU A CD2 1 
ATOM   390   N  N   . SER A 1 67  ? 115.188 114.969 140.438 1.00 73.96  ?  56  SER A N   1 
ATOM   391   C  CA  . SER A 1 67  ? 116.480 115.625 140.563 1.00 73.96  ?  56  SER A CA  1 
ATOM   392   C  C   . SER A 1 67  ? 116.919 115.692 142.016 1.00 73.96  ?  56  SER A C   1 
ATOM   393   O  O   . SER A 1 67  ? 118.104 115.533 142.319 1.00 73.96  ?  56  SER A O   1 
ATOM   394   C  CB  . SER A 1 67  ? 116.406 117.022 139.959 1.00 73.96  ?  56  SER A CB  1 
ATOM   395   O  OG  . SER A 1 67  ? 117.690 117.506 139.630 1.00 73.96  ?  56  SER A OG  1 
ATOM   396   N  N   . LEU A 1 68  ? 115.979 115.930 142.926 1.00 67.53  ?  57  LEU A N   1 
ATOM   397   C  CA  . LEU A 1 68  ? 116.301 116.044 144.340 1.00 67.53  ?  57  LEU A CA  1 
ATOM   398   C  C   . LEU A 1 68  ? 116.508 114.702 145.014 1.00 67.53  ?  57  LEU A C   1 
ATOM   399   O  O   . LEU A 1 68  ? 117.125 114.651 146.079 1.00 67.53  ?  57  LEU A O   1 
ATOM   400   C  CB  . LEU A 1 68  ? 115.199 116.798 145.075 1.00 67.53  ?  57  LEU A CB  1 
ATOM   401   C  CG  . LEU A 1 68  ? 115.115 118.298 144.836 1.00 67.53  ?  57  LEU A CG  1 
ATOM   402   C  CD1 . LEU A 1 68  ? 114.001 118.886 145.667 1.00 67.53  ?  57  LEU A CD1 1 
ATOM   403   C  CD2 . LEU A 1 68  ? 116.434 118.952 145.169 1.00 67.53  ?  57  LEU A CD2 1 
ATOM   404   N  N   . PHE A 1 69  ? 116.009 113.623 144.427 1.00 63.63  ?  58  PHE A N   1 
ATOM   405   C  CA  . PHE A 1 69  ? 116.077 112.288 145.015 1.00 63.63  ?  58  PHE A CA  1 
ATOM   406   C  C   . PHE A 1 69  ? 116.642 111.347 143.966 1.00 63.63  ?  58  PHE A C   1 
ATOM   407   O  O   . PHE A 1 69  ? 115.919 110.522 143.399 1.00 63.63  ?  58  PHE A O   1 
ATOM   408   C  CB  . PHE A 1 69  ? 114.696 111.838 145.484 1.00 63.63  ?  58  PHE A CB  1 
ATOM   409   C  CG  . PHE A 1 69  ? 114.716 111.001 146.715 1.00 63.63  ?  58  PHE A CG  1 
ATOM   410   C  CD1 . PHE A 1 69  ? 114.168 109.732 146.711 1.00 63.63  ?  58  PHE A CD1 1 
ATOM   411   C  CD2 . PHE A 1 69  ? 115.271 111.480 147.882 1.00 63.63  ?  58  PHE A CD2 1 
ATOM   412   C  CE1 . PHE A 1 69  ? 114.179 108.955 147.847 1.00 63.63  ?  58  PHE A CE1 1 
ATOM   413   C  CE2 . PHE A 1 69  ? 115.288 110.708 149.019 1.00 63.63  ?  58  PHE A CE2 1 
ATOM   414   C  CZ  . PHE A 1 69  ? 114.741 109.444 149.003 1.00 63.63  ?  58  PHE A CZ  1 
ATOM   415   N  N   . PRO A 1 70  ? 117.954 111.477 143.677 1.00 58.42  ?  59  PRO A N   1 
ATOM   416   C  CA  . PRO A 1 70  ? 118.530 110.695 142.573 1.00 58.42  ?  59  PRO A CA  1 
ATOM   417   C  C   . PRO A 1 70  ? 118.462 109.168 142.700 1.00 58.42  ?  59  PRO A C   1 
ATOM   418   O  O   . PRO A 1 70  ? 118.565 108.490 141.683 1.00 58.42  ?  59  PRO A O   1 
ATOM   419   C  CB  . PRO A 1 70  ? 119.996 111.156 142.563 1.00 58.42  ?  59  PRO A CB  1 
ATOM   420   C  CG  . PRO A 1 70  ? 120.016 112.451 143.297 1.00 58.42  ?  59  PRO A CG  1 
ATOM   421   C  CD  . PRO A 1 70  ? 118.986 112.279 144.360 1.00 58.42  ?  59  PRO A CD  1 
ATOM   422   N  N   . ILE A 1 71  ? 118.296 108.636 143.902 1.00 58.56  ?  60  ILE A N   1 
ATOM   423   C  CA  . ILE A 1 71  ? 118.278 107.192 144.080 1.00 58.56  ?  60  ILE A CA  1 
ATOM   424   C  C   . ILE A 1 71  ? 117.080 106.566 143.378 1.00 58.56  ?  60  ILE A C   1 
ATOM   425   O  O   . ILE A 1 71  ? 117.156 105.429 142.924 1.00 58.56  ?  60  ILE A O   1 
ATOM   426   C  CB  . ILE A 1 71  ? 118.294 106.808 145.575 1.00 58.56  ?  60  ILE A CB  1 
ATOM   427   C  CG1 . ILE A 1 71  ? 118.544 105.308 145.740 1.00 58.56  ?  60  ILE A CG1 1 
ATOM   428   C  CG2 . ILE A 1 71  ? 117.002 107.238 146.254 1.00 58.56  ?  60  ILE A CG2 1 
ATOM   429   C  CD1 . ILE A 1 71  ? 118.767 104.886 147.174 1.00 58.56  ?  60  ILE A CD1 1 
ATOM   430   N  N   . ALA A 1 72  ? 115.984 107.308 143.268 1.00 60.98  ?  61  ALA A N   1 
ATOM   431   C  CA  . ALA A 1 72  ? 114.774 106.799 142.622 1.00 60.98  ?  61  ALA A CA  1 
ATOM   432   C  C   . ALA A 1 72  ? 114.964 106.561 141.136 1.00 60.98  ?  61  ALA A C   1 
ATOM   433   O  O   . ALA A 1 72  ? 114.126 105.941 140.495 1.00 60.98  ?  61  ALA A O   1 
ATOM   434   C  CB  . ALA A 1 72  ? 113.624 107.757 142.847 1.00 60.98  ?  61  ALA A CB  1 
ATOM   435   N  N   . SER A 1 73  ? 116.057 107.062 140.584 1.00 62.08  ?  62  SER A N   1 
ATOM   436   C  CA  . SER A 1 73  ? 116.332 106.869 139.174 1.00 62.08  ?  62  SER A CA  1 
ATOM   437   C  C   . SER A 1 73  ? 117.433 105.837 138.915 1.00 62.08  ?  62  SER A C   1 
ATOM   438   O  O   . SER A 1 73  ? 117.385 105.132 137.910 1.00 62.08  ?  62  SER A O   1 
ATOM   439   C  CB  . SER A 1 73  ? 116.705 108.205 138.539 1.00 62.08  ?  62  SER A CB  1 
ATOM   440   O  OG  . SER A 1 73  ? 117.878 108.739 139.122 1.00 62.08  ?  62  SER A OG  1 
ATOM   441   N  N   . TRP A 1 74  ? 118.418 105.737 139.802 1.00 59.29  ?  63  TRP A N   1 
ATOM   442   C  CA  . TRP A 1 74  ? 119.534 104.824 139.553 1.00 59.29  ?  63  TRP A CA  1 
ATOM   443   C  C   . TRP A 1 74  ? 119.331 103.454 140.183 1.00 59.29  ?  63  TRP A C   1 
ATOM   444   O  O   . TRP A 1 74  ? 119.820 102.453 139.668 1.00 59.29  ?  63  TRP A O   1 
ATOM   445   C  CB  . TRP A 1 74  ? 120.878 105.424 140.001 1.00 59.29  ?  63  TRP A CB  1 
ATOM   446   C  CG  . TRP A 1 74  ? 121.092 105.572 141.482 1.00 59.29  ?  63  TRP A CG  1 
ATOM   447   C  CD1 . TRP A 1 74  ? 120.950 106.711 142.216 1.00 59.29  ?  63  TRP A CD1 1 
ATOM   448   C  CD2 . TRP A 1 74  ? 121.532 104.559 142.398 1.00 59.29  ?  63  TRP A CD2 1 
ATOM   449   N  NE1 . TRP A 1 74  ? 121.253 106.469 143.532 1.00 59.29  ?  63  TRP A NE1 1 
ATOM   450   C  CE2 . TRP A 1 74  ? 121.612 105.155 143.670 1.00 59.29  ?  63  TRP A CE2 1 
ATOM   451   C  CE3 . TRP A 1 74  ? 121.855 103.206 142.266 1.00 59.29  ?  63  TRP A CE3 1 
ATOM   452   C  CZ2 . TRP A 1 74  ? 122.002 104.445 144.803 1.00 59.29  ?  63  TRP A CZ2 1 
ATOM   453   C  CZ3 . TRP A 1 74  ? 122.239 102.504 143.391 1.00 59.29  ?  63  TRP A CZ3 1 
ATOM   454   C  CH2 . TRP A 1 74  ? 122.310 103.124 144.643 1.00 59.29  ?  63  TRP A CH2 1 
ATOM   455   N  N   . LEU A 1 75  ? 118.618 103.407 141.296 1.00 61.94  ?  64  LEU A N   1 
ATOM   456   C  CA  . LEU A 1 75  ? 118.385 102.138 141.961 1.00 61.94  ?  64  LEU A CA  1 
ATOM   457   C  C   . LEU A 1 75  ? 117.530 101.209 141.104 1.00 61.94  ?  64  LEU A C   1 
ATOM   458   O  O   . LEU A 1 75  ? 117.868 100.041 140.930 1.00 61.94  ?  64  LEU A O   1 
ATOM   459   C  CB  . LEU A 1 75  ? 117.738 102.346 143.331 1.00 61.94  ?  64  LEU A CB  1 
ATOM   460   C  CG  . LEU A 1 75  ? 117.681 101.099 144.210 1.00 61.94  ?  64  LEU A CG  1 
ATOM   461   C  CD1 . LEU A 1 75  ? 119.072 100.508 144.372 1.00 61.94  ?  64  LEU A CD1 1 
ATOM   462   C  CD2 . LEU A 1 75  ? 117.075 101.430 145.562 1.00 61.94  ?  64  LEU A CD2 1 
ATOM   463   N  N   . PRO A 1 76  ? 116.422 101.727 140.554 1.00 63.55  ?  65  PRO A N   1 
ATOM   464   C  CA  . PRO A 1 76  ? 115.544 100.886 139.736 1.00 63.55  ?  65  PRO A CA  1 
ATOM   465   C  C   . PRO A 1 76  ? 116.252 100.332 138.509 1.00 63.55  ?  65  PRO A C   1 
ATOM   466   O  O   . PRO A 1 76  ? 115.856 99.288  138.006 1.00 63.55  ?  65  PRO A O   1 
ATOM   467   C  CB  . PRO A 1 76  ? 114.444 101.857 139.311 1.00 63.55  ?  65  PRO A CB  1 
ATOM   468   C  CG  . PRO A 1 76  ? 114.410 102.877 140.389 1.00 63.55  ?  65  PRO A CG  1 
ATOM   469   C  CD  . PRO A 1 76  ? 115.847 103.067 140.766 1.00 63.55  ?  65  PRO A CD  1 
ATOM   470   N  N   . ALA A 1 77  ? 117.285 101.012 138.039 1.00 65.10  ?  66  ALA A N   1 
ATOM   471   C  CA  . ALA A 1 77  ? 118.005 100.568 136.856 1.00 65.10  ?  66  ALA A CA  1 
ATOM   472   C  C   . ALA A 1 77  ? 119.280 99.832  137.216 1.00 65.10  ?  66  ALA A C   1 
ATOM   473   O  O   . ALA A 1 77  ? 120.240 99.845  136.451 1.00 65.10  ?  66  ALA A O   1 
ATOM   474   C  CB  . ALA A 1 77  ? 118.331 101.758 135.979 1.00 65.10  ?  66  ALA A CB  1 
ATOM   475   N  N   . TYR A 1 78  ? 119.299 99.188  138.374 1.00 65.09  ?  67  TYR A N   1 
ATOM   476   C  CA  . TYR A 1 78  ? 120.506 98.513  138.824 1.00 65.09  ?  67  TYR A CA  1 
ATOM   477   C  C   . TYR A 1 78  ? 120.718 97.201  138.102 1.00 65.09  ?  67  TYR A C   1 
ATOM   478   O  O   . TYR A 1 78  ? 119.788 96.414  137.957 1.00 65.09  ?  67  TYR A O   1 
ATOM   479   C  CB  . TYR A 1 78  ? 120.436 98.265  140.329 1.00 65.09  ?  67  TYR A CB  1 
ATOM   480   C  CG  . TYR A 1 78  ? 121.749 97.850  140.949 1.00 65.09  ?  67  TYR A CG  1 
ATOM   481   C  CD1 . TYR A 1 78  ? 122.650 98.799  141.410 1.00 65.09  ?  67  TYR A CD1 1 
ATOM   482   C  CD2 . TYR A 1 78  ? 122.084 96.511  141.080 1.00 65.09  ?  67  TYR A CD2 1 
ATOM   483   C  CE1 . TYR A 1 78  ? 123.850 98.425  141.979 1.00 65.09  ?  67  TYR A CE1 1 
ATOM   484   C  CE2 . TYR A 1 78  ? 123.281 96.128  141.649 1.00 65.09  ?  67  TYR A CE2 1 
ATOM   485   C  CZ  . TYR A 1 78  ? 124.158 97.090  142.097 1.00 65.09  ?  67  TYR A CZ  1 
ATOM   486   O  OH  . TYR A 1 78  ? 125.349 96.713  142.665 1.00 65.09  ?  67  TYR A OH  1 
ATOM   487   N  N   . ARG A 1 79  ? 121.939 96.958  137.649 1.00 70.32  ?  68  ARG A N   1 
ATOM   488   C  CA  . ARG A 1 79  ? 122.253 95.707  136.985 1.00 70.32  ?  68  ARG A CA  1 
ATOM   489   C  C   . ARG A 1 79  ? 122.780 94.719  138.002 1.00 70.32  ?  68  ARG A C   1 
ATOM   490   O  O   . ARG A 1 79  ? 123.987 94.567  138.144 1.00 70.32  ?  68  ARG A O   1 
ATOM   491   C  CB  . ARG A 1 79  ? 123.292 95.945  135.901 1.00 70.32  ?  68  ARG A CB  1 
ATOM   492   C  CG  . ARG A 1 79  ? 122.983 97.130  135.006 1.00 70.32  ?  68  ARG A CG  1 
ATOM   493   C  CD  . ARG A 1 79  ? 123.945 97.163  133.837 1.00 70.32  ?  68  ARG A CD  1 
ATOM   494   N  NE  . ARG A 1 79  ? 125.299 96.843  134.271 1.00 70.32  ?  68  ARG A NE  1 
ATOM   495   C  CZ  . ARG A 1 79  ? 126.342 96.748  133.456 1.00 70.32  ?  68  ARG A CZ  1 
ATOM   496   N  NH1 . ARG A 1 79  ? 127.537 96.450  133.943 1.00 70.32  1  68  ARG A NH1 1 
ATOM   497   N  NH2 . ARG A 1 79  ? 126.190 96.950  132.155 1.00 70.32  ?  68  ARG A NH2 1 
ATOM   498   N  N   . LEU A 1 80  ? 121.889 94.022  138.692 1.00 69.79  ?  69  LEU A N   1 
ATOM   499   C  CA  . LEU A 1 80  ? 122.314 93.116  139.763 1.00 69.79  ?  69  LEU A CA  1 
ATOM   500   C  C   . LEU A 1 80  ? 123.381 92.120  139.358 1.00 69.79  ?  69  LEU A C   1 
ATOM   501   O  O   . LEU A 1 80  ? 124.376 91.968  140.054 1.00 69.79  ?  69  LEU A O   1 
ATOM   502   C  CB  . LEU A 1 80  ? 121.110 92.350  140.313 1.00 69.79  ?  69  LEU A CB  1 
ATOM   503   C  CG  . LEU A 1 80  ? 120.230 93.128  141.288 1.00 69.79  ?  69  LEU A CG  1 
ATOM   504   C  CD1 . LEU A 1 80  ? 119.011 92.307  141.678 1.00 69.79  ?  69  LEU A CD1 1 
ATOM   505   C  CD2 . LEU A 1 80  ? 121.035 93.509  142.520 1.00 69.79  ?  69  LEU A CD2 1 
ATOM   506   N  N   . LYS A 1 81  ? 123.186 91.439  138.242 1.00 73.86  ?  70  LYS A N   1 
ATOM   507   C  CA  . LYS A 1 81  ? 124.131 90.411  137.829 1.00 73.86  ?  70  LYS A CA  1 
ATOM   508   C  C   . LYS A 1 81  ? 125.512 90.970  137.540 1.00 73.86  ?  70  LYS A C   1 
ATOM   509   O  O   . LYS A 1 81  ? 126.515 90.311  137.799 1.00 73.86  ?  70  LYS A O   1 
ATOM   510   C  CB  . LYS A 1 81  ? 123.605 89.682  136.595 1.00 73.86  ?  70  LYS A CB  1 
ATOM   511   C  CG  . LYS A 1 81  ? 122.209 89.112  136.773 1.00 73.86  ?  70  LYS A CG  1 
ATOM   512   C  CD  . LYS A 1 81  ? 122.127 88.226  138.006 1.00 73.86  ?  70  LYS A CD  1 
ATOM   513   C  CE  . LYS A 1 81  ? 120.712 87.713  138.221 1.00 73.86  ?  70  LYS A CE  1 
ATOM   514   N  NZ  . LYS A 1 81  ? 120.597 86.887  139.454 1.00 73.86  1  70  LYS A NZ  1 
ATOM   515   N  N   . GLU A 1 82  ? 125.578 92.179  137.003 1.00 73.52  ?  71  GLU A N   1 
ATOM   516   C  CA  . GLU A 1 82  ? 126.865 92.739  136.624 1.00 73.52  ?  71  GLU A CA  1 
ATOM   517   C  C   . GLU A 1 82  ? 127.411 93.717  137.639 1.00 73.52  ?  71  GLU A C   1 
ATOM   518   O  O   . GLU A 1 82  ? 128.543 94.176  137.505 1.00 73.52  ?  71  GLU A O   1 
ATOM   519   C  CB  . GLU A 1 82  ? 126.740 93.460  135.282 1.00 73.52  ?  71  GLU A CB  1 
ATOM   520   C  CG  . GLU A 1 82  ? 126.016 92.674  134.201 1.00 73.52  ?  71  GLU A CG  1 
ATOM   521   C  CD  . GLU A 1 82  ? 124.521 92.927  134.187 1.00 73.52  ?  71  GLU A CD  1 
ATOM   522   O  OE1 . GLU A 1 82  ? 123.883 92.835  135.256 1.00 73.52  ?  71  GLU A OE1 1 
ATOM   523   O  OE2 . GLU A 1 82  ? 123.981 93.211  133.098 1.00 73.52  -1 71  GLU A OE2 1 
ATOM   524   N  N   . TRP A 1 83  ? 126.632 94.078  138.652 1.00 65.28  ?  72  TRP A N   1 
ATOM   525   C  CA  . TRP A 1 83  ? 127.090 95.114  139.583 1.00 65.28  ?  72  TRP A CA  1 
ATOM   526   C  C   . TRP A 1 83  ? 127.109 94.735  141.052 1.00 65.28  ?  72  TRP A C   1 
ATOM   527   O  O   . TRP A 1 83  ? 127.907 95.278  141.808 1.00 65.28  ?  72  TRP A O   1 
ATOM   528   C  CB  . TRP A 1 83  ? 126.221 96.361  139.436 1.00 65.28  ?  72  TRP A CB  1 
ATOM   529   C  CG  . TRP A 1 83  ? 126.486 97.169  138.227 1.00 65.28  ?  72  TRP A CG  1 
ATOM   530   C  CD1 . TRP A 1 83  ? 127.480 96.987  137.316 1.00 65.28  ?  72  TRP A CD1 1 
ATOM   531   C  CD2 . TRP A 1 83  ? 125.748 98.312  137.798 1.00 65.28  ?  72  TRP A CD2 1 
ATOM   532   N  NE1 . TRP A 1 83  ? 127.403 97.947  136.339 1.00 65.28  ?  72  TRP A NE1 1 
ATOM   533   C  CE2 . TRP A 1 83  ? 126.346 98.773  136.612 1.00 65.28  ?  72  TRP A CE2 1 
ATOM   534   C  CE3 . TRP A 1 83  ? 124.635 98.990  138.300 1.00 65.28  ?  72  TRP A CE3 1 
ATOM   535   C  CZ2 . TRP A 1 83  ? 125.870 99.881  135.921 1.00 65.28  ?  72  TRP A CZ2 1 
ATOM   536   C  CZ3 . TRP A 1 83  ? 124.163 100.087 137.613 1.00 65.28  ?  72  TRP A CZ3 1 
ATOM   537   C  CH2 . TRP A 1 83  ? 124.780 100.523 136.436 1.00 65.28  ?  72  TRP A CH2 1 
ATOM   538   N  N   . LEU A 1 84  ? 126.254 93.817  141.475 1.00 62.82  ?  73  LEU A N   1 
ATOM   539   C  CA  . LEU A 1 84  ? 126.167 93.508  142.905 1.00 62.82  ?  73  LEU A CA  1 
ATOM   540   C  C   . LEU A 1 84  ? 127.483 93.045  143.530 1.00 62.82  ?  73  LEU A C   1 
ATOM   541   O  O   . LEU A 1 84  ? 127.912 93.597  144.535 1.00 62.82  ?  73  LEU A O   1 
ATOM   542   C  CB  . LEU A 1 84  ? 125.082 92.464  143.165 1.00 62.82  ?  73  LEU A CB  1 
ATOM   543   C  CG  . LEU A 1 84  ? 124.714 92.293  144.637 1.00 62.82  ?  73  LEU A CG  1 
ATOM   544   C  CD1 . LEU A 1 84  ? 124.390 93.641  145.259 1.00 62.82  ?  73  LEU A CD1 1 
ATOM   545   C  CD2 . LEU A 1 84  ? 123.548 91.331  144.791 1.00 62.82  ?  73  LEU A CD2 1 
ATOM   546   N  N   . LEU A 1 85  ? 128.130 92.051  142.943 1.00 60.50  ?  74  LEU A N   1 
ATOM   547   C  CA  . LEU A 1 85  ? 129.355 91.522  143.532 1.00 60.50  ?  74  LEU A CA  1 
ATOM   548   C  C   . LEU A 1 85  ? 130.445 92.572  143.557 1.00 60.50  ?  74  LEU A C   1 
ATOM   549   O  O   . LEU A 1 85  ? 131.216 92.645  144.511 1.00 60.50  ?  74  LEU A O   1 
ATOM   550   C  CB  . LEU A 1 85  ? 129.843 90.290  142.774 1.00 60.50  ?  74  LEU A CB  1 
ATOM   551   C  CG  . LEU A 1 85  ? 131.035 89.581  143.413 1.00 60.50  ?  74  LEU A CG  1 
ATOM   552   C  CD1 . LEU A 1 85  ? 130.683 89.131  144.821 1.00 60.50  ?  74  LEU A CD1 1 
ATOM   553   C  CD2 . LEU A 1 85  ? 131.479 88.401  142.566 1.00 60.50  ?  74  LEU A CD2 1 
ATOM   554   N  N   . SER A 1 86  ? 130.515 93.386  142.512 1.00 58.66  ?  75  SER A N   1 
ATOM   555   C  CA  . SER A 1 86  ? 131.536 94.421  142.439 1.00 58.66  ?  75  SER A CA  1 
ATOM   556   C  C   . SER A 1 86  ? 131.337 95.433  143.543 1.00 58.66  ?  75  SER A C   1 
ATOM   557   O  O   . SER A 1 86  ? 132.283 95.808  144.228 1.00 58.66  ?  75  SER A O   1 
ATOM   558   C  CB  . SER A 1 86  ? 131.494 95.112  141.081 1.00 58.66  ?  75  SER A CB  1 
ATOM   559   O  OG  . SER A 1 86  ? 131.769 94.196  140.039 1.00 58.66  ?  75  SER A OG  1 
ATOM   560   N  N   . ASP A 1 87  ? 130.102 95.865  143.729 1.00 56.06  ?  76  ASP A N   1 
ATOM   561   C  CA  . ASP A 1 87  ? 129.804 96.838  144.765 1.00 56.06  ?  76  ASP A CA  1 
ATOM   562   C  C   . ASP A 1 87  ? 130.021 96.245  146.150 1.00 56.06  ?  76  ASP A C   1 
ATOM   563   O  O   . ASP A 1 87  ? 130.506 96.926  147.045 1.00 56.06  ?  76  ASP A O   1 
ATOM   564   C  CB  . ASP A 1 87  ? 128.375 97.358  144.603 1.00 56.06  ?  76  ASP A CB  1 
ATOM   565   C  CG  . ASP A 1 87  ? 128.282 98.505  143.628 1.00 56.06  ?  76  ASP A CG  1 
ATOM   566   O  OD1 . ASP A 1 87  ? 129.320 99.132  143.349 1.00 56.06  ?  76  ASP A OD1 1 
ATOM   567   O  OD2 . ASP A 1 87  ? 127.169 98.789  143.150 1.00 56.06  -1 76  ASP A OD2 1 
ATOM   568   N  N   . ILE A 1 88  ? 129.677 94.976  146.328 1.00 54.77  ?  77  ILE A N   1 
ATOM   569   C  CA  . ILE A 1 88  ? 129.893 94.321  147.614 1.00 54.77  ?  77  ILE A CA  1 
ATOM   570   C  C   . ILE A 1 88  ? 131.371 94.266  147.968 1.00 54.77  ?  77  ILE A C   1 
ATOM   571   O  O   . ILE A 1 88  ? 131.761 94.632  149.072 1.00 54.77  ?  77  ILE A O   1 
ATOM   572   C  CB  . ILE A 1 88  ? 129.327 92.896  147.627 1.00 54.77  ?  77  ILE A CB  1 
ATOM   573   C  CG1 . ILE A 1 88  ? 127.808 92.929  147.472 1.00 54.77  ?  77  ILE A CG1 1 
ATOM   574   C  CG2 . ILE A 1 88  ? 129.708 92.186  148.914 1.00 54.77  ?  77  ILE A CG2 1 
ATOM   575   C  CD1 . ILE A 1 88  ? 127.177 91.558  147.387 1.00 54.77  ?  77  ILE A CD1 1 
ATOM   576   N  N   . VAL A 1 89  ? 132.198 93.835  147.027 1.00 53.70  ?  78  VAL A N   1 
ATOM   577   C  CA  . VAL A 1 89  ? 133.629 93.744  147.276 1.00 53.70  ?  78  VAL A CA  1 
ATOM   578   C  C   . VAL A 1 89  ? 134.246 95.115  147.472 1.00 53.70  ?  78  VAL A C   1 
ATOM   579   O  O   . VAL A 1 89  ? 135.069 95.305  148.361 1.00 53.70  ?  78  VAL A O   1 
ATOM   580   C  CB  . VAL A 1 89  ? 134.345 93.021  146.125 1.00 53.70  ?  78  VAL A CB  1 
ATOM   581   C  CG1 . VAL A 1 89  ? 135.852 93.104  146.291 1.00 53.70  ?  78  VAL A CG1 1 
ATOM   582   C  CG2 . VAL A 1 89  ? 133.883 91.576  146.040 1.00 53.70  ?  78  VAL A CG2 1 
ATOM   583   N  N   . SER A 1 90  ? 133.860 96.076  146.648 1.00 52.32  ?  79  SER A N   1 
ATOM   584   C  CA  . SER A 1 90  ? 134.379 97.423  146.777 1.00 52.32  ?  79  SER A CA  1 
ATOM   585   C  C   . SER A 1 90  ? 133.938 98.045  148.088 1.00 52.32  ?  79  SER A C   1 
ATOM   586   O  O   . SER A 1 90  ? 134.689 98.796  148.698 1.00 52.32  ?  79  SER A O   1 
ATOM   587   C  CB  . SER A 1 90  ? 133.915 98.276  145.605 1.00 52.32  ?  79  SER A CB  1 
ATOM   588   O  OG  . SER A 1 90  ? 134.259 99.633  145.794 1.00 52.32  ?  79  SER A OG  1 
ATOM   589   N  N   . GLY A 1 91  ? 132.723 97.741  148.524 1.00 50.83  ?  80  GLY A N   1 
ATOM   590   C  CA  . GLY A 1 91  ? 132.210 98.291  149.760 1.00 50.83  ?  80  GLY A CA  1 
ATOM   591   C  C   . GLY A 1 91  ? 132.929 97.790  150.984 1.00 50.83  ?  80  GLY A C   1 
ATOM   592   O  O   . GLY A 1 91  ? 133.207 98.553  151.899 1.00 50.83  ?  80  GLY A O   1 
ATOM   593   N  N   . ILE A 1 92  ? 133.237 96.504  151.010 1.00 50.73  ?  81  ILE A N   1 
ATOM   594   C  CA  . ILE A 1 92  ? 133.962 95.943  152.130 1.00 50.73  ?  81  ILE A CA  1 
ATOM   595   C  C   . ILE A 1 92  ? 135.326 96.584  152.203 1.00 50.73  ?  81  ILE A C   1 
ATOM   596   O  O   . ILE A 1 92  ? 135.797 96.943  153.281 1.00 50.73  ?  81  ILE A O   1 
ATOM   597   C  CB  . ILE A 1 92  ? 134.131 94.426  151.994 1.00 50.73  ?  81  ILE A CB  1 
ATOM   598   C  CG1 . ILE A 1 92  ? 132.779 93.748  151.782 1.00 50.73  ?  81  ILE A CG1 1 
ATOM   599   C  CG2 . ILE A 1 92  ? 134.821 93.860  153.224 1.00 50.73  ?  81  ILE A CG2 1 
ATOM   600   C  CD1 . ILE A 1 92  ? 131.812 93.941  152.926 1.00 50.73  ?  81  ILE A CD1 1 
ATOM   601   N  N   . SER A 1 93  ? 135.960 96.748  151.054 1.00 51.12  ?  82  SER A N   1 
ATOM   602   C  CA  . SER A 1 93  ? 137.282 97.336  151.024 1.00 51.12  ?  82  SER A CA  1 
ATOM   603   C  C   . SER A 1 93  ? 137.258 98.772  151.509 1.00 51.12  ?  82  SER A C   1 
ATOM   604   O  O   . SER A 1 93  ? 138.057 99.160  152.356 1.00 51.12  ?  82  SER A O   1 
ATOM   605   C  CB  . SER A 1 93  ? 137.837 97.270  149.605 1.00 51.12  ?  82  SER A CB  1 
ATOM   606   O  OG  . SER A 1 93  ? 137.832 95.942  149.119 1.00 51.12  ?  82  SER A OG  1 
ATOM   607   N  N   . THR A 1 94  ? 136.335 99.560  150.986 1.00 49.89  ?  83  THR A N   1 
ATOM   608   C  CA  . THR A 1 94  ? 136.256 100.959 151.361 1.00 49.89  ?  83  THR A CA  1 
ATOM   609   C  C   . THR A 1 94  ? 135.795 101.095 152.798 1.00 49.89  ?  83  THR A C   1 
ATOM   610   O  O   . THR A 1 94  ? 136.182 102.031 153.484 1.00 49.89  ?  83  THR A O   1 
ATOM   611   C  CB  . THR A 1 94  ? 135.314 101.726 150.414 1.00 49.89  ?  83  THR A CB  1 
ATOM   612   O  OG1 . THR A 1 94  ? 135.506 101.261 149.074 1.00 49.89  ?  83  THR A OG1 1 
ATOM   613   C  CG2 . THR A 1 94  ? 135.597 103.213 150.476 1.00 49.89  ?  83  THR A CG2 1 
ATOM   614   N  N   . GLY A 1 95  ? 134.973 100.162 153.259 1.00 49.21  ?  84  GLY A N   1 
ATOM   615   C  CA  . GLY A 1 95  ? 134.496 100.193 154.627 1.00 49.21  ?  84  GLY A CA  1 
ATOM   616   C  C   . GLY A 1 95  ? 135.615 100.078 155.626 1.00 49.21  ?  84  GLY A C   1 
ATOM   617   O  O   . GLY A 1 95  ? 135.627 100.792 156.623 1.00 49.21  ?  84  GLY A O   1 
ATOM   618   N  N   . ILE A 1 96  ? 136.563 99.190  155.371 1.00 49.77  ?  85  ILE A N   1 
ATOM   619   C  CA  . ILE A 1 96  ? 137.714 99.053  156.247 1.00 49.77  ?  85  ILE A CA  1 
ATOM   620   C  C   . ILE A 1 96  ? 138.550 100.322 156.260 1.00 49.77  ?  85  ILE A C   1 
ATOM   621   O  O   . ILE A 1 96  ? 138.942 100.801 157.320 1.00 49.77  ?  85  ILE A O   1 
ATOM   622   C  CB  . ILE A 1 96  ? 138.594 97.873  155.811 1.00 49.77  ?  85  ILE A CB  1 
ATOM   623   C  CG1 . ILE A 1 96  ? 137.794 96.573  155.871 1.00 49.77  ?  85  ILE A CG1 1 
ATOM   624   C  CG2 . ILE A 1 96  ? 139.834 97.781  156.684 1.00 49.77  ?  85  ILE A CG2 1 
ATOM   625   C  CD1 . ILE A 1 96  ? 138.568 95.360  155.409 1.00 49.77  ?  85  ILE A CD1 1 
ATOM   626   N  N   . VAL A 1 97  ? 138.809 100.879 155.087 1.00 49.45  ?  86  VAL A N   1 
ATOM   627   C  CA  . VAL A 1 97  ? 139.594 102.097 155.003 1.00 49.45  ?  86  VAL A CA  1 
ATOM   628   C  C   . VAL A 1 97  ? 138.886 103.211 155.739 1.00 49.45  ?  86  VAL A C   1 
ATOM   629   O  O   . VAL A 1 97  ? 139.523 103.998 156.425 1.00 49.45  ?  86  VAL A O   1 
ATOM   630   C  CB  . VAL A 1 97  ? 139.837 102.508 153.540 1.00 49.45  ?  86  VAL A CB  1 
ATOM   631   C  CG1 . VAL A 1 97  ? 140.627 103.804 153.470 1.00 49.45  ?  86  VAL A CG1 1 
ATOM   632   C  CG2 . VAL A 1 97  ? 140.562 101.401 152.794 1.00 49.45  ?  86  VAL A CG2 1 
ATOM   633   N  N   . ALA A 1 98  ? 137.569 103.272 155.618 1.00 48.60  ?  87  ALA A N   1 
ATOM   634   C  CA  . ALA A 1 98  ? 136.798 104.317 156.269 1.00 48.60  ?  87  ALA A CA  1 
ATOM   635   C  C   . ALA A 1 98  ? 136.928 104.236 157.774 1.00 48.60  ?  87  ALA A C   1 
ATOM   636   O  O   . ALA A 1 98  ? 137.055 105.253 158.445 1.00 48.60  ?  87  ALA A O   1 
ATOM   637   C  CB  . ALA A 1 98  ? 135.345 104.214 155.857 1.00 48.60  ?  87  ALA A CB  1 
ATOM   638   N  N   . VAL A 1 99  ? 136.904 103.026 158.306 1.00 47.31  ?  88  VAL A N   1 
ATOM   639   C  CA  . VAL A 1 99  ? 137.022 102.843 159.739 1.00 47.31  ?  88  VAL A CA  1 
ATOM   640   C  C   . VAL A 1 99  ? 138.363 103.343 160.235 1.00 47.31  ?  88  VAL A C   1 
ATOM   641   O  O   . VAL A 1 99  ? 138.430 104.080 161.212 1.00 47.31  ?  88  VAL A O   1 
ATOM   642   C  CB  . VAL A 1 99  ? 136.856 101.367 160.135 1.00 47.31  ?  88  VAL A CB  1 
ATOM   643   C  CG1 . VAL A 1 99  ? 137.244 101.151 161.589 1.00 47.31  ?  88  VAL A CG1 1 
ATOM   644   C  CG2 . VAL A 1 99  ? 135.432 100.904 159.872 1.00 47.31  ?  88  VAL A CG2 1 
ATOM   645   N  N   . LEU A 1 100 ? 139.433 102.954 159.558 1.00 48.87  ?  89  LEU A N   1 
ATOM   646   C  CA  . LEU A 1 100 ? 140.763 103.350 159.993 1.00 48.87  ?  89  LEU A CA  1 
ATOM   647   C  C   . LEU A 1 100 ? 141.008 104.825 159.760 1.00 48.87  ?  89  LEU A C   1 
ATOM   648   O  O   . LEU A 1 100 ? 141.586 105.498 160.602 1.00 48.87  ?  89  LEU A O   1 
ATOM   649   C  CB  . LEU A 1 100 ? 141.821 102.510 159.286 1.00 48.87  ?  89  LEU A CB  1 
ATOM   650   C  CG  . LEU A 1 100 ? 141.858 101.043 159.708 1.00 48.87  ?  89  LEU A CG  1 
ATOM   651   C  CD1 . LEU A 1 100 ? 142.738 100.225 158.778 1.00 48.87  ?  89  LEU A CD1 1 
ATOM   652   C  CD2 . LEU A 1 100 ? 142.325 100.923 161.150 1.00 48.87  ?  89  LEU A CD2 1 
ATOM   653   N  N   . GLN A 1 101 ? 140.572 105.330 158.618 1.00 49.02  ?  90  GLN A N   1 
ATOM   654   C  CA  . GLN A 1 101 ? 140.730 106.740 158.330 1.00 49.02  ?  90  GLN A CA  1 
ATOM   655   C  C   . GLN A 1 101 ? 139.841 107.572 159.242 1.00 49.02  ?  90  GLN A C   1 
ATOM   656   O  O   . GLN A 1 101 ? 140.223 108.667 159.618 1.00 49.02  ?  90  GLN A O   1 
ATOM   657   C  CB  . GLN A 1 101 ? 140.446 107.031 156.861 1.00 49.02  ?  90  GLN A CB  1 
ATOM   658   C  CG  . GLN A 1 101 ? 141.528 106.570 155.906 1.00 49.02  ?  90  GLN A CG  1 
ATOM   659   C  CD  . GLN A 1 101 ? 141.308 107.090 154.502 1.00 49.02  ?  90  GLN A CD  1 
ATOM   660   O  OE1 . GLN A 1 101 ? 140.265 107.663 154.201 1.00 49.02  ?  90  GLN A OE1 1 
ATOM   661   N  NE2 . GLN A 1 101 ? 142.289 106.891 153.635 1.00 49.02  ?  90  GLN A NE2 1 
ATOM   662   N  N   . GLY A 1 102 ? 138.663 107.071 159.608 1.00 47.83  ?  91  GLY A N   1 
ATOM   663   C  CA  . GLY A 1 102 ? 137.856 107.799 160.565 1.00 47.83  ?  91  GLY A CA  1 
ATOM   664   C  C   . GLY A 1 102 ? 138.545 107.950 161.901 1.00 47.83  ?  91  GLY A C   1 
ATOM   665   O  O   . GLY A 1 102 ? 138.555 109.034 162.481 1.00 47.83  ?  91  GLY A O   1 
ATOM   666   N  N   . LEU A 1 103 ? 139.146 106.869 162.398 1.00 48.51  ?  92  LEU A N   1 
ATOM   667   C  CA  . LEU A 1 103 ? 139.900 106.959 163.646 1.00 48.51  ?  92  LEU A CA  1 
ATOM   668   C  C   . LEU A 1 103 ? 141.044 107.967 163.538 1.00 48.51  ?  92  LEU A C   1 
ATOM   669   O  O   . LEU A 1 103 ? 141.212 108.840 164.405 1.00 48.51  ?  92  LEU A O   1 
ATOM   670   C  CB  . LEU A 1 103 ? 140.431 105.584 164.034 1.00 48.51  ?  92  LEU A CB  1 
ATOM   671   C  CG  . LEU A 1 103 ? 139.422 104.470 164.281 1.00 48.51  ?  92  LEU A CG  1 
ATOM   672   C  CD1 . LEU A 1 103 ? 140.146 103.172 164.506 1.00 48.51  ?  92  LEU A CD1 1 
ATOM   673   C  CD2 . LEU A 1 103 ? 138.547 104.790 165.455 1.00 48.51  ?  92  LEU A CD2 1 
ATOM   674   N  N   . ALA A 1 104 ? 141.834 107.873 162.468 1.00 48.18  ?  93  ALA A N   1 
ATOM   675   C  CA  . ALA A 1 104 ? 142.974 108.772 162.310 1.00 48.18  ?  93  ALA A CA  1 
ATOM   676   C  C   . ALA A 1 104 ? 142.535 110.227 162.186 1.00 48.18  ?  93  ALA A C   1 
ATOM   677   O  O   . ALA A 1 104 ? 143.139 111.130 162.780 1.00 48.18  ?  93  ALA A O   1 
ATOM   678   C  CB  . ALA A 1 104 ? 143.793 108.354 161.095 1.00 48.18  ?  93  ALA A CB  1 
ATOM   679   N  N   . PHE A 1 105 ? 141.483 110.486 161.427 1.00 47.27  ?  94  PHE A N   1 
ATOM   680   C  CA  . PHE A 1 105 ? 141.102 111.870 161.218 1.00 47.27  ?  94  PHE A CA  1 
ATOM   681   C  C   . PHE A 1 105 ? 140.380 112.433 162.431 1.00 47.27  ?  94  PHE A C   1 
ATOM   682   O  O   . PHE A 1 105 ? 140.401 113.648 162.648 1.00 47.27  ?  94  PHE A O   1 
ATOM   683   C  CB  . PHE A 1 105 ? 140.266 111.989 159.946 1.00 47.27  ?  94  PHE A CB  1 
ATOM   684   C  CG  . PHE A 1 105 ? 140.937 111.424 158.722 1.00 47.27  ?  94  PHE A CG  1 
ATOM   685   C  CD1 . PHE A 1 105 ? 142.302 111.209 158.691 1.00 47.27  ?  94  PHE A CD1 1 
ATOM   686   C  CD2 . PHE A 1 105 ? 140.202 111.104 157.604 1.00 47.27  ?  94  PHE A CD2 1 
ATOM   687   C  CE1 . PHE A 1 105 ? 142.907 110.681 157.582 1.00 47.27  ?  94  PHE A CE1 1 
ATOM   688   C  CE2 . PHE A 1 105 ? 140.807 110.587 156.492 1.00 47.27  ?  94  PHE A CE2 1 
ATOM   689   C  CZ  . PHE A 1 105 ? 142.158 110.374 156.481 1.00 47.27  ?  94  PHE A CZ  1 
ATOM   690   N  N   . ALA A 1 106 ? 139.773 111.576 163.253 1.00 47.94  ?  95  ALA A N   1 
ATOM   691   C  CA  . ALA A 1 106 ? 139.299 112.027 164.553 1.00 47.94  ?  95  ALA A CA  1 
ATOM   692   C  C   . ALA A 1 106 ? 140.463 112.428 165.440 1.00 47.94  ?  95  ALA A C   1 
ATOM   693   O  O   . ALA A 1 106 ? 140.349 113.366 166.234 1.00 47.94  ?  95  ALA A O   1 
ATOM   694   C  CB  . ALA A 1 106 ? 138.470 110.939 165.224 1.00 47.94  ?  95  ALA A CB  1 
ATOM   695   N  N   . LEU A 1 107 ? 141.589 111.719 165.335 1.00 50.17  ?  96  LEU A N   1 
ATOM   696   C  CA  . LEU A 1 107 ? 142.806 112.209 165.978 1.00 50.17  ?  96  LEU A CA  1 
ATOM   697   C  C   . LEU A 1 107 ? 143.158 113.607 165.490 1.00 50.17  ?  96  LEU A C   1 
ATOM   698   O  O   . LEU A 1 107 ? 143.551 114.469 166.279 1.00 50.17  ?  96  LEU A O   1 
ATOM   699   C  CB  . LEU A 1 107 ? 143.976 111.269 165.718 1.00 50.17  ?  96  LEU A CB  1 
ATOM   700   C  CG  . LEU A 1 107 ? 144.012 109.915 166.403 1.00 50.17  ?  96  LEU A CG  1 
ATOM   701   C  CD1 . LEU A 1 107 ? 145.372 109.314 166.192 1.00 50.17  ?  96  LEU A CD1 1 
ATOM   702   C  CD2 . LEU A 1 107 ? 143.704 110.066 167.863 1.00 50.17  ?  96  LEU A CD2 1 
ATOM   703   N  N   . LEU A 1 108 ? 143.033 113.846 164.186 1.00 50.89  ?  97  LEU A N   1 
ATOM   704   C  CA  . LEU A 1 108 ? 143.334 115.175 163.652 1.00 50.89  ?  97  LEU A CA  1 
ATOM   705   C  C   . LEU A 1 108 ? 142.383 116.247 164.175 1.00 50.89  ?  97  LEU A C   1 
ATOM   706   O  O   . LEU A 1 108 ? 142.761 117.417 164.257 1.00 50.89  ?  97  LEU A O   1 
ATOM   707   C  CB  . LEU A 1 108 ? 143.291 115.158 162.129 1.00 50.89  ?  97  LEU A CB  1 
ATOM   708   C  CG  . LEU A 1 108 ? 144.528 114.628 161.426 1.00 50.89  ?  97  LEU A CG  1 
ATOM   709   C  CD1 . LEU A 1 108 ? 144.393 114.835 159.945 1.00 50.89  ?  97  LEU A CD1 1 
ATOM   710   C  CD2 . LEU A 1 108 ? 145.759 115.317 161.956 1.00 50.89  ?  97  LEU A CD2 1 
ATOM   711   N  N   . VAL A 1 109 ? 141.135 115.887 164.489 1.00 51.89  ?  98  VAL A N   1 
ATOM   712   C  CA  . VAL A 1 109 ? 140.204 116.836 165.096 1.00 51.89  ?  98  VAL A CA  1 
ATOM   713   C  C   . VAL A 1 109 ? 140.443 116.992 166.592 1.00 51.89  ?  98  VAL A C   1 
ATOM   714   O  O   . VAL A 1 109 ? 139.914 117.929 167.202 1.00 51.89  ?  98  VAL A O   1 
ATOM   715   C  CB  . VAL A 1 109 ? 138.744 116.414 164.812 1.00 51.89  ?  98  VAL A CB  1 
ATOM   716   C  CG1 . VAL A 1 109 ? 137.772 117.492 165.213 1.00 51.89  ?  98  VAL A CG1 1 
ATOM   717   C  CG2 . VAL A 1 109 ? 138.559 116.118 163.359 1.00 51.89  ?  98  VAL A CG2 1 
ATOM   718   N  N   . ASP A 1 110 ? 141.245 116.115 167.193 1.00 56.61  ?  99  ASP A N   1 
ATOM   719   C  CA  . ASP A 1 110 ? 141.562 116.144 168.621 1.00 56.61  ?  99  ASP A CA  1 
ATOM   720   C  C   . ASP A 1 110 ? 140.318 115.870 169.461 1.00 56.61  ?  99  ASP A C   1 
ATOM   721   O  O   . ASP A 1 110 ? 140.032 116.558 170.438 1.00 56.61  ?  99  ASP A O   1 
ATOM   722   C  CB  . ASP A 1 110 ? 142.225 117.465 169.017 1.00 56.61  ?  99  ASP A CB  1 
ATOM   723   C  CG  . ASP A 1 110 ? 142.791 117.442 170.419 1.00 56.61  ?  99  ASP A CG  1 
ATOM   724   O  OD1 . ASP A 1 110 ? 142.992 116.338 170.959 1.00 56.61  ?  99  ASP A OD1 1 
ATOM   725   O  OD2 . ASP A 1 110 ? 143.044 118.528 170.980 1.00 56.61  -1 99  ASP A OD2 1 
ATOM   726   N  N   . ILE A 1 111 ? 139.570 114.849 169.062 1.00 53.54  ?  100 ILE A N   1 
ATOM   727   C  CA  . ILE A 1 111 ? 138.455 114.321 169.844 1.00 53.54  ?  100 ILE A CA  1 
ATOM   728   C  C   . ILE A 1 111 ? 138.615 112.818 169.926 1.00 53.54  ?  100 ILE A C   1 
ATOM   729   O  O   . ILE A 1 111 ? 139.454 112.235 169.217 1.00 53.54  ?  100 ILE A O   1 
ATOM   730   C  CB  . ILE A 1 111 ? 137.091 114.701 169.224 1.00 53.54  ?  100 ILE A CB  1 
ATOM   731   C  CG1 . ILE A 1 111 ? 136.975 114.173 167.799 1.00 53.54  ?  100 ILE A CG1 1 
ATOM   732   C  CG2 . ILE A 1 111 ? 136.891 116.198 169.260 1.00 53.54  ?  100 ILE A CG2 1 
ATOM   733   C  CD1 . ILE A 1 111 ? 135.724 114.590 167.113 1.00 53.54  ?  100 ILE A CD1 1 
ATOM   734   N  N   . PRO A 1 112 ? 137.876 112.151 170.808 1.00 53.57  ?  101 PRO A N   1 
ATOM   735   C  CA  . PRO A 1 112 ? 137.940 110.690 170.881 1.00 53.57  ?  101 PRO A CA  1 
ATOM   736   C  C   . PRO A 1 112 ? 137.679 110.057 169.526 1.00 53.57  ?  101 PRO A C   1 
ATOM   737   O  O   . PRO A 1 112 ? 136.858 110.556 168.745 1.00 53.57  ?  101 PRO A O   1 
ATOM   738   C  CB  . PRO A 1 112 ? 136.837 110.345 171.884 1.00 53.57  ?  101 PRO A CB  1 
ATOM   739   C  CG  . PRO A 1 112 ? 136.806 111.504 172.774 1.00 53.57  ?  101 PRO A CG  1 
ATOM   740   C  CD  . PRO A 1 112 ? 137.117 112.708 171.942 1.00 53.57  ?  101 PRO A CD  1 
ATOM   741   N  N   . PRO A 1 113 ? 138.359 108.951 169.210 1.00 53.32  ?  102 PRO A N   1 
ATOM   742   C  CA  . PRO A 1 113 ? 138.336 108.430 167.835 1.00 53.32  ?  102 PRO A CA  1 
ATOM   743   C  C   . PRO A 1 113 ? 137.026 107.800 167.377 1.00 53.32  ?  102 PRO A C   1 
ATOM   744   O  O   . PRO A 1 113 ? 136.899 107.524 166.180 1.00 53.32  ?  102 PRO A O   1 
ATOM   745   C  CB  . PRO A 1 113 ? 139.465 107.389 167.846 1.00 53.32  ?  102 PRO A CB  1 
ATOM   746   C  CG  . PRO A 1 113 ? 139.666 107.050 169.251 1.00 53.32  ?  102 PRO A CG  1 
ATOM   747   C  CD  . PRO A 1 113 ? 139.379 108.283 170.029 1.00 53.32  ?  102 PRO A CD  1 
ATOM   748   N  N   . VAL A 1 114 ? 136.051 107.568 168.254 1.00 51.93  ?  103 VAL A N   1 
ATOM   749   C  CA  . VAL A 1 114 ? 134.786 106.991 167.806 1.00 51.93  ?  103 VAL A CA  1 
ATOM   750   C  C   . VAL A 1 114 ? 133.949 107.993 167.016 1.00 51.93  ?  103 VAL A C   1 
ATOM   751   O  O   . VAL A 1 114 ? 133.128 107.601 166.170 1.00 51.93  ?  103 VAL A O   1 
ATOM   752   C  CB  . VAL A 1 114 ? 134.007 106.439 169.012 1.00 51.93  ?  103 VAL A CB  1 
ATOM   753   C  CG1 . VAL A 1 114 ? 133.528 107.560 169.902 1.00 51.93  ?  103 VAL A CG1 1 
ATOM   754   C  CG2 . VAL A 1 114 ? 132.851 105.576 168.561 1.00 51.93  ?  103 VAL A CG2 1 
ATOM   755   N  N   . TYR A 1 115 ? 134.153 109.284 167.244 1.00 51.66  ?  104 TYR A N   1 
ATOM   756   C  CA  . TYR A 1 115 ? 133.432 110.282 166.481 1.00 51.66  ?  104 TYR A CA  1 
ATOM   757   C  C   . TYR A 1 115 ? 133.877 110.307 165.030 1.00 51.66  ?  104 TYR A C   1 
ATOM   758   O  O   . TYR A 1 115 ? 133.098 110.702 164.159 1.00 51.66  ?  104 TYR A O   1 
ATOM   759   C  CB  . TYR A 1 115 ? 133.595 111.635 167.162 1.00 51.66  ?  104 TYR A CB  1 
ATOM   760   C  CG  . TYR A 1 115 ? 133.113 111.590 168.591 1.00 51.66  ?  104 TYR A CG  1 
ATOM   761   C  CD1 . TYR A 1 115 ? 131.771 111.726 168.892 1.00 51.66  ?  104 TYR A CD1 1 
ATOM   762   C  CD2 . TYR A 1 115 ? 133.989 111.369 169.633 1.00 51.66  ?  104 TYR A CD2 1 
ATOM   763   C  CE1 . TYR A 1 115 ? 131.324 111.666 170.178 1.00 51.66  ?  104 TYR A CE1 1 
ATOM   764   C  CE2 . TYR A 1 115 ? 133.547 111.306 170.926 1.00 51.66  ?  104 TYR A CE2 1 
ATOM   765   C  CZ  . TYR A 1 115 ? 132.213 111.455 171.191 1.00 51.66  ?  104 TYR A CZ  1 
ATOM   766   O  OH  . TYR A 1 115 ? 131.761 111.397 172.483 1.00 51.66  ?  104 TYR A OH  1 
ATOM   767   N  N   . GLY A 1 116 ? 135.089 109.838 164.741 1.00 49.30  ?  105 GLY A N   1 
ATOM   768   C  CA  . GLY A 1 116 ? 135.473 109.610 163.364 1.00 49.30  ?  105 GLY A CA  1 
ATOM   769   C  C   . GLY A 1 116 ? 134.693 108.487 162.724 1.00 49.30  ?  105 GLY A C   1 
ATOM   770   O  O   . GLY A 1 116 ? 134.404 108.531 161.528 1.00 49.30  ?  105 GLY A O   1 
ATOM   771   N  N   . LEU A 1 117 ? 134.321 107.480 163.508 1.00 48.09  ?  106 LEU A N   1 
ATOM   772   C  CA  . LEU A 1 117 ? 133.438 106.441 163.002 1.00 48.09  ?  106 LEU A CA  1 
ATOM   773   C  C   . LEU A 1 117 ? 132.057 106.997 162.698 1.00 48.09  ?  106 LEU A C   1 
ATOM   774   O  O   . LEU A 1 117 ? 131.445 106.642 161.685 1.00 48.09  ?  106 LEU A O   1 
ATOM   775   C  CB  . LEU A 1 117 ? 133.352 105.301 164.008 1.00 48.09  ?  106 LEU A CB  1 
ATOM   776   C  CG  . LEU A 1 117 ? 134.650 104.559 164.299 1.00 48.09  ?  106 LEU A CG  1 
ATOM   777   C  CD1 . LEU A 1 117 ? 134.405 103.456 165.294 1.00 48.09  ?  106 LEU A CD1 1 
ATOM   778   C  CD2 . LEU A 1 117 ? 135.233 104.003 163.027 1.00 48.09  ?  106 LEU A CD2 1 
ATOM   779   N  N   . TYR A 1 118 ? 131.548 107.878 163.560 1.00 49.61  ?  107 TYR A N   1 
ATOM   780   C  CA  . TYR A 1 118 ? 130.282 108.542 163.253 1.00 49.61  ?  107 TYR A CA  1 
ATOM   781   C  C   . TYR A 1 118 ? 130.380 109.348 161.964 1.00 49.61  ?  107 TYR A C   1 
ATOM   782   O  O   . TYR A 1 118 ? 129.435 109.385 161.161 1.00 49.61  ?  107 TYR A O   1 
ATOM   783   C  CB  . TYR A 1 118 ? 129.871 109.454 164.403 1.00 49.61  ?  107 TYR A CB  1 
ATOM   784   C  CG  . TYR A 1 118 ? 129.719 108.764 165.723 1.00 49.61  ?  107 TYR A CG  1 
ATOM   785   C  CD1 . TYR A 1 118 ? 129.407 107.423 165.793 1.00 49.61  ?  107 TYR A CD1 1 
ATOM   786   C  CD2 . TYR A 1 118 ? 129.886 109.457 166.904 1.00 49.61  ?  107 TYR A CD2 1 
ATOM   787   C  CE1 . TYR A 1 118 ? 129.270 106.796 166.994 1.00 49.61  ?  107 TYR A CE1 1 
ATOM   788   C  CE2 . TYR A 1 118 ? 129.750 108.836 168.109 1.00 49.61  ?  107 TYR A CE2 1 
ATOM   789   C  CZ  . TYR A 1 118 ? 129.439 107.508 168.149 1.00 49.61  ?  107 TYR A CZ  1 
ATOM   790   O  OH  . TYR A 1 118 ? 129.300 106.877 169.356 1.00 49.61  ?  107 TYR A OH  1 
ATOM   791   N  N   . ALA A 1 119 ? 131.512 110.025 161.769 1.00 48.37  ?  108 ALA A N   1 
ATOM   792   C  CA  . ALA A 1 119 ? 131.724 110.823 160.570 1.00 48.37  ?  108 ALA A CA  1 
ATOM   793   C  C   . ALA A 1 119 ? 131.851 109.959 159.326 1.00 48.37  ?  108 ALA A C   1 
ATOM   794   O  O   . ALA A 1 119 ? 131.535 110.415 158.226 1.00 48.37  ?  108 ALA A O   1 
ATOM   795   C  CB  . ALA A 1 119 ? 132.961 111.696 160.740 1.00 48.37  ?  108 ALA A CB  1 
ATOM   796   N  N   . SER A 1 120 ? 132.333 108.730 159.470 1.00 48.13  ?  109 SER A N   1 
ATOM   797   C  CA  . SER A 1 120 ? 132.349 107.804 158.347 1.00 48.13  ?  109 SER A CA  1 
ATOM   798   C  C   . SER A 1 120 ? 131.002 107.147 158.101 1.00 48.13  ?  109 SER A C   1 
ATOM   799   O  O   . SER A 1 120 ? 130.787 106.601 157.017 1.00 48.13  ?  109 SER A O   1 
ATOM   800   C  CB  . SER A 1 120 ? 133.393 106.715 158.565 1.00 48.13  ?  109 SER A CB  1 
ATOM   801   O  OG  . SER A 1 120 ? 134.563 107.246 159.132 1.00 48.13  ?  109 SER A OG  1 
ATOM   802   N  N   . PHE A 1 121 ? 130.107 107.156 159.082 1.00 47.19  ?  110 PHE A N   1 
ATOM   803   C  CA  . PHE A 1 121 ? 128.825 106.490 158.898 1.00 47.19  ?  110 PHE A CA  1 
ATOM   804   C  C   . PHE A 1 121 ? 127.745 107.402 158.325 1.00 47.19  ?  110 PHE A C   1 
ATOM   805   O  O   . PHE A 1 121 ? 127.151 107.082 157.296 1.00 47.19  ?  110 PHE A O   1 
ATOM   806   C  CB  . PHE A 1 121 ? 128.344 105.899 160.221 1.00 47.19  ?  110 PHE A CB  1 
ATOM   807   C  CG  . PHE A 1 121 ? 127.038 105.185 160.118 1.00 47.19  ?  110 PHE A CG  1 
ATOM   808   C  CD1 . PHE A 1 121 ? 126.950 103.976 159.468 1.00 47.19  ?  110 PHE A CD1 1 
ATOM   809   C  CD2 . PHE A 1 121 ? 125.899 105.720 160.670 1.00 47.19  ?  110 PHE A CD2 1 
ATOM   810   C  CE1 . PHE A 1 121 ? 125.756 103.320 159.370 1.00 47.19  ?  110 PHE A CE1 1 
ATOM   811   C  CE2 . PHE A 1 121 ? 124.703 105.064 160.574 1.00 47.19  ?  110 PHE A CE2 1 
ATOM   812   C  CZ  . PHE A 1 121 ? 124.634 103.863 159.923 1.00 47.19  ?  110 PHE A CZ  1 
ATOM   813   N  N   . PHE A 1 122 ? 127.359 108.446 159.041 1.00 47.44  ?  111 PHE A N   1 
ATOM   814   C  CA  . PHE A 1 122 ? 126.192 109.254 158.625 1.00 47.44  ?  111 PHE A CA  1 
ATOM   815   C  C   . PHE A 1 122 ? 126.215 109.959 157.263 1.00 47.44  ?  111 PHE A C   1 
ATOM   816   O  O   . PHE A 1 122 ? 125.253 109.852 156.503 1.00 47.44  ?  111 PHE A O   1 
ATOM   817   C  CB  . PHE A 1 122 ? 125.853 110.264 159.734 1.00 47.44  ?  111 PHE A CB  1 
ATOM   818   C  CG  . PHE A 1 122 ? 125.390 109.621 161.007 1.00 47.44  ?  111 PHE A CG  1 
ATOM   819   C  CD1 . PHE A 1 122 ? 124.115 109.098 161.105 1.00 47.44  ?  111 PHE A CD1 1 
ATOM   820   C  CD2 . PHE A 1 122 ? 126.230 109.530 162.099 1.00 47.44  ?  111 PHE A CD2 1 
ATOM   821   C  CE1 . PHE A 1 122 ? 123.684 108.495 162.268 1.00 47.44  ?  111 PHE A CE1 1 
ATOM   822   C  CE2 . PHE A 1 122 ? 125.808 108.928 163.269 1.00 47.44  ?  111 PHE A CE2 1 
ATOM   823   C  CZ  . PHE A 1 122 ? 124.531 108.409 163.354 1.00 47.44  ?  111 PHE A CZ  1 
ATOM   824   N  N   . PRO A 1 123 ? 127.284 110.689 156.957 1.00 46.52  ?  112 PRO A N   1 
ATOM   825   C  CA  . PRO A 1 123 ? 127.234 111.362 155.662 1.00 46.52  ?  112 PRO A CA  1 
ATOM   826   C  C   . PRO A 1 123 ? 127.033 110.375 154.510 1.00 46.52  ?  112 PRO A C   1 
ATOM   827   O  O   . PRO A 1 123 ? 126.300 110.683 153.581 1.00 46.52  ?  112 PRO A O   1 
ATOM   828   C  CB  . PRO A 1 123 ? 128.601 112.032 155.575 1.00 46.52  ?  112 PRO A CB  1 
ATOM   829   C  CG  . PRO A 1 123 ? 128.999 112.252 156.995 1.00 46.52  ?  112 PRO A CG  1 
ATOM   830   C  CD  . PRO A 1 123 ? 128.469 111.069 157.744 1.00 46.52  ?  112 PRO A CD  1 
ATOM   831   N  N   . ALA A 1 124 ? 127.659 109.206 154.574 1.00 46.48  ?  113 ALA A N   1 
ATOM   832   C  CA  . ALA A 1 124 ? 127.549 108.219 153.506 1.00 46.48  ?  113 ALA A CA  1 
ATOM   833   C  C   . ALA A 1 124 ? 126.133 107.697 153.299 1.00 46.48  ?  113 ALA A C   1 
ATOM   834   O  O   . ALA A 1 124 ? 125.692 107.523 152.168 1.00 46.48  ?  113 ALA A O   1 
ATOM   835   C  CB  . ALA A 1 124 ? 128.497 107.063 153.778 1.00 46.48  ?  113 ALA A CB  1 
ATOM   836   N  N   . ILE A 1 125 ? 125.422 107.433 154.382 1.00 48.11  ?  114 ILE A N   1 
ATOM   837   C  CA  . ILE A 1 125 ? 124.057 106.951 154.287 1.00 48.11  ?  114 ILE A CA  1 
ATOM   838   C  C   . ILE A 1 125 ? 123.161 107.986 153.631 1.00 48.11  ?  114 ILE A C   1 
ATOM   839   O  O   . ILE A 1 125 ? 122.326 107.648 152.799 1.00 48.11  ?  114 ILE A O   1 
ATOM   840   C  CB  . ILE A 1 125 ? 123.509 106.590 155.678 1.00 48.11  ?  114 ILE A CB  1 
ATOM   841   C  CG1 . ILE A 1 125 ? 124.306 105.433 156.275 1.00 48.11  ?  114 ILE A CG1 1 
ATOM   842   C  CG2 . ILE A 1 125 ? 122.032 106.235 155.602 1.00 48.11  ?  114 ILE A CG2 1 
ATOM   843   C  CD1 . ILE A 1 125 ? 124.181 104.150 155.490 1.00 48.11  ?  114 ILE A CD1 1 
ATOM   844   N  N   . ILE A 1 126 ? 123.384 109.250 153.942 1.00 47.36  ?  115 ILE A N   1 
ATOM   845   C  CA  . ILE A 1 126 ? 122.605 110.319 153.358 1.00 47.36  ?  115 ILE A CA  1 
ATOM   846   C  C   . ILE A 1 126 ? 122.906 110.471 151.882 1.00 47.36  ?  115 ILE A C   1 
ATOM   847   O  O   . ILE A 1 126 ? 122.009 110.635 151.084 1.00 47.36  ?  115 ILE A O   1 
ATOM   848   C  CB  . ILE A 1 126 ? 122.843 111.660 154.072 1.00 47.36  ?  115 ILE A CB  1 
ATOM   849   C  CG1 . ILE A 1 126 ? 122.353 111.586 155.512 1.00 47.36  ?  115 ILE A CG1 1 
ATOM   850   C  CG2 . ILE A 1 126 ? 122.134 112.784 153.345 1.00 47.36  ?  115 ILE A CG2 1 
ATOM   851   C  CD1 . ILE A 1 126 ? 120.987 110.968 155.660 1.00 47.36  ?  115 ILE A CD1 1 
ATOM   852   N  N   . TYR A 1 127 ? 124.174 110.354 151.515 1.00 46.55  ?  116 TYR A N   1 
ATOM   853   C  CA  . TYR A 1 127 ? 124.620 110.490 150.138 1.00 46.55  ?  116 TYR A CA  1 
ATOM   854   C  C   . TYR A 1 127 ? 124.013 109.437 149.232 1.00 46.55  ?  116 TYR A C   1 
ATOM   855   O  O   . TYR A 1 127 ? 123.770 109.690 148.071 1.00 46.55  ?  116 TYR A O   1 
ATOM   856   C  CB  . TYR A 1 127 ? 126.142 110.482 150.042 1.00 46.55  ?  116 TYR A CB  1 
ATOM   857   C  CG  . TYR A 1 127 ? 126.631 111.061 148.752 1.00 46.55  ?  116 TYR A CG  1 
ATOM   858   C  CD1 . TYR A 1 127 ? 126.816 112.418 148.617 1.00 46.55  ?  116 TYR A CD1 1 
ATOM   859   C  CD2 . TYR A 1 127 ? 126.854 110.255 147.650 1.00 46.55  ?  116 TYR A CD2 1 
ATOM   860   C  CE1 . TYR A 1 127 ? 127.245 112.955 147.436 1.00 46.55  ?  116 TYR A CE1 1 
ATOM   861   C  CE2 . TYR A 1 127 ? 127.280 110.787 146.458 1.00 46.55  ?  116 TYR A CE2 1 
ATOM   862   C  CZ  . TYR A 1 127 ? 127.477 112.136 146.367 1.00 46.55  ?  116 TYR A CZ  1 
ATOM   863   O  OH  . TYR A 1 127 ? 127.885 112.682 145.195 1.00 46.55  ?  116 TYR A OH  1 
ATOM   864   N  N   . LEU A 1 128 ? 123.863 108.231 149.751 1.00 49.89  ?  117 LEU A N   1 
ATOM   865   C  CA  . LEU A 1 128 ? 123.230 107.151 149.041 1.00 49.89  ?  117 LEU A CA  1 
ATOM   866   C  C   . LEU A 1 128 ? 121.865 107.599 148.552 1.00 49.89  ?  117 LEU A C   1 
ATOM   867   O  O   . LEU A 1 128 ? 121.450 107.231 147.469 1.00 49.89  ?  117 LEU A O   1 
ATOM   868   C  CB  . LEU A 1 128 ? 123.070 105.955 149.968 1.00 49.89  ?  117 LEU A CB  1 
ATOM   869   C  CG  . LEU A 1 128 ? 122.207 104.800 149.484 1.00 49.89  ?  117 LEU A CG  1 
ATOM   870   C  CD1 . LEU A 1 128 ? 122.966 103.952 148.483 1.00 49.89  ?  117 LEU A CD1 1 
ATOM   871   C  CD2 . LEU A 1 128 ? 121.767 103.978 150.672 1.00 49.89  ?  117 LEU A CD2 1 
ATOM   872   N  N   . PHE A 1 129 ? 121.153 108.400 149.339 1.00 51.89  ?  118 PHE A N   1 
ATOM   873   C  CA  . PHE A 1 129 ? 119.845 108.831 148.872 1.00 51.89  ?  118 PHE A CA  1 
ATOM   874   C  C   . PHE A 1 129 ? 119.899 110.107 148.053 1.00 51.89  ?  118 PHE A C   1 
ATOM   875   O  O   . PHE A 1 129 ? 119.163 110.239 147.073 1.00 51.89  ?  118 PHE A O   1 
ATOM   876   C  CB  . PHE A 1 129 ? 118.906 109.044 150.056 1.00 51.89  ?  118 PHE A CB  1 
ATOM   877   C  CG  . PHE A 1 129 ? 118.577 107.797 150.791 1.00 51.89  ?  118 PHE A CG  1 
ATOM   878   C  CD1 . PHE A 1 129 ? 117.670 106.903 150.276 1.00 51.89  ?  118 PHE A CD1 1 
ATOM   879   C  CD2 . PHE A 1 129 ? 119.169 107.519 152.001 1.00 51.89  ?  118 PHE A CD2 1 
ATOM   880   C  CE1 . PHE A 1 129 ? 117.364 105.757 150.950 1.00 51.89  ?  118 PHE A CE1 1 
ATOM   881   C  CE2 . PHE A 1 129 ? 118.865 106.374 152.678 1.00 51.89  ?  118 PHE A CE2 1 
ATOM   882   C  CZ  . PHE A 1 129 ? 117.962 105.491 152.152 1.00 51.89  ?  118 PHE A CZ  1 
ATOM   883   N  N   . PHE A 1 130 ? 120.790 111.039 148.341 1.00 52.18  ?  119 PHE A N   1 
ATOM   884   C  CA  . PHE A 1 130 ? 120.768 112.283 147.579 1.00 52.18  ?  119 PHE A CA  1 
ATOM   885   C  C   . PHE A 1 130 ? 121.892 112.588 146.607 1.00 52.18  ?  119 PHE A C   1 
ATOM   886   O  O   . PHE A 1 130 ? 121.806 113.549 145.881 1.00 52.18  ?  119 PHE A O   1 
ATOM   887   C  CB  . PHE A 1 130 ? 120.609 113.465 148.539 1.00 52.18  ?  119 PHE A CB  1 
ATOM   888   C  CG  . PHE A 1 130 ? 119.413 113.360 149.429 1.00 52.18  ?  119 PHE A CG  1 
ATOM   889   C  CD1 . PHE A 1 130 ? 118.197 113.865 149.031 1.00 52.18  ?  119 PHE A CD1 1 
ATOM   890   C  CD2 . PHE A 1 130 ? 119.501 112.741 150.657 1.00 52.18  ?  119 PHE A CD2 1 
ATOM   891   C  CE1 . PHE A 1 130 ? 117.096 113.767 149.846 1.00 52.18  ?  119 PHE A CE1 1 
ATOM   892   C  CE2 . PHE A 1 130 ? 118.403 112.636 151.473 1.00 52.18  ?  119 PHE A CE2 1 
ATOM   893   C  CZ  . PHE A 1 130 ? 117.197 113.149 151.067 1.00 52.18  ?  119 PHE A CZ  1 
ATOM   894   N  N   . GLY A 1 131 ? 122.960 111.813 146.620 1.00 50.25  ?  120 GLY A N   1 
ATOM   895   C  CA  . GLY A 1 131 ? 124.081 112.072 145.743 1.00 50.25  ?  120 GLY A CA  1 
ATOM   896   C  C   . GLY A 1 131 ? 123.941 111.676 144.298 1.00 50.25  ?  120 GLY A C   1 
ATOM   897   O  O   . GLY A 1 131 ? 123.218 110.751 143.988 1.00 50.25  ?  120 GLY A O   1 
ATOM   898   N  N   . THR A 1 132 ? 124.608 112.390 143.403 1.00 52.04  ?  121 THR A N   1 
ATOM   899   C  CA  . THR A 1 132 ? 124.564 112.027 141.991 1.00 52.04  ?  121 THR A CA  1 
ATOM   900   C  C   . THR A 1 132 ? 125.827 111.313 141.527 1.00 52.04  ?  121 THR A C   1 
ATOM   901   O  O   . THR A 1 132 ? 125.852 110.750 140.451 1.00 52.04  ?  121 THR A O   1 
ATOM   902   C  CB  . THR A 1 132 ? 124.225 113.209 141.058 1.00 52.04  ?  121 THR A CB  1 
ATOM   903   O  OG1 . THR A 1 132 ? 125.378 114.023 140.854 1.00 52.04  ?  121 THR A OG1 1 
ATOM   904   C  CG2 . THR A 1 132 ? 123.116 114.038 141.636 1.00 52.04  ?  121 THR A CG2 1 
ATOM   905   N  N   . SER A 1 133 ? 126.878 111.361 142.331 1.00 49.99  ?  122 SER A N   1 
ATOM   906   C  CA  . SER A 1 133 ? 128.113 110.677 142.005 1.00 49.99  ?  122 SER A CA  1 
ATOM   907   C  C   . SER A 1 133 ? 127.957 109.216 142.332 1.00 49.99  ?  122 SER A C   1 
ATOM   908   O  O   . SER A 1 133 ? 127.248 108.861 143.248 1.00 49.99  ?  122 SER A O   1 
ATOM   909   C  CB  . SER A 1 133 ? 129.284 111.259 142.773 1.00 49.99  ?  122 SER A CB  1 
ATOM   910   O  OG  . SER A 1 133 ? 130.432 110.466 142.607 1.00 49.99  ?  122 SER A OG  1 
ATOM   911   N  N   . ARG A 1 134 ? 128.637 108.361 141.594 1.00 51.20  ?  123 ARG A N   1 
ATOM   912   C  CA  . ARG A 1 134 ? 128.521 106.940 141.836 1.00 51.20  ?  123 ARG A CA  1 
ATOM   913   C  C   . ARG A 1 134 ? 129.805 106.326 142.305 1.00 51.20  ?  123 ARG A C   1 
ATOM   914   O  O   . ARG A 1 134 ? 129.881 105.133 142.452 1.00 51.20  ?  123 ARG A O   1 
ATOM   915   C  CB  . ARG A 1 134 ? 128.158 106.256 140.527 1.00 51.20  ?  123 ARG A CB  1 
ATOM   916   C  CG  . ARG A 1 134 ? 126.852 106.719 139.929 1.00 51.20  ?  123 ARG A CG  1 
ATOM   917   C  CD  . ARG A 1 134 ? 126.773 106.364 138.470 1.00 51.20  ?  123 ARG A CD  1 
ATOM   918   N  NE  . ARG A 1 134 ? 127.565 105.185 138.184 1.00 51.20  ?  123 ARG A NE  1 
ATOM   919   C  CZ  . ARG A 1 134 ? 127.716 104.671 136.970 1.00 51.20  ?  123 ARG A CZ  1 
ATOM   920   N  NH1 . ARG A 1 134 ? 128.455 103.588 136.794 1.00 51.20  1  123 ARG A NH1 1 
ATOM   921   N  NH2 . ARG A 1 134 ? 127.124 105.240 135.933 1.00 51.20  ?  123 ARG A NH2 1 
ATOM   922   N  N   . HIS A 1 135 ? 130.832 107.127 142.558 1.00 49.22  ?  124 HIS A N   1 
ATOM   923   C  CA  . HIS A 1 135 ? 132.140 106.555 142.809 1.00 49.22  ?  124 HIS A CA  1 
ATOM   924   C  C   . HIS A 1 135 ? 132.889 107.137 143.995 1.00 49.22  ?  124 HIS A C   1 
ATOM   925   O  O   . HIS A 1 135 ? 133.890 106.546 144.401 1.00 49.22  ?  124 HIS A O   1 
ATOM   926   C  CB  . HIS A 1 135 ? 133.012 106.684 141.553 1.00 49.22  ?  124 HIS A CB  1 
ATOM   927   C  CG  . HIS A 1 135 ? 132.546 105.831 140.420 1.00 49.22  ?  124 HIS A CG  1 
ATOM   928   N  ND1 . HIS A 1 135 ? 131.753 106.313 139.405 1.00 49.22  ?  124 HIS A ND1 1 
ATOM   929   C  CD2 . HIS A 1 135 ? 132.733 104.519 140.160 1.00 49.22  ?  124 HIS A CD2 1 
ATOM   930   C  CE1 . HIS A 1 135 ? 131.477 105.334 138.565 1.00 49.22  ?  124 HIS A CE1 1 
ATOM   931   N  NE2 . HIS A 1 135 ? 132.062 104.237 138.999 1.00 49.22  ?  124 HIS A NE2 1 
ATOM   932   N  N   . ILE A 1 136 ? 132.461 108.244 144.561 1.00 45.88  ?  125 ILE A N   1 
ATOM   933   C  CA  . ILE A 1 136 ? 133.189 108.827 145.680 1.00 45.88  ?  125 ILE A CA  1 
ATOM   934   C  C   . ILE A 1 136 ? 132.755 108.152 146.968 1.00 45.88  ?  125 ILE A C   1 
ATOM   935   O  O   . ILE A 1 136 ? 131.601 107.748 147.125 1.00 45.88  ?  125 ILE A O   1 
ATOM   936   C  CB  . ILE A 1 136 ? 132.997 110.352 145.757 1.00 45.88  ?  125 ILE A CB  1 
ATOM   937   C  CG1 . ILE A 1 136 ? 131.538 110.718 146.006 1.00 45.88  ?  125 ILE A CG1 1 
ATOM   938   C  CG2 . ILE A 1 136 ? 133.549 111.016 144.518 1.00 45.88  ?  125 ILE A CG2 1 
ATOM   939   C  CD1 . ILE A 1 136 ? 131.353 112.121 146.492 1.00 45.88  ?  125 ILE A CD1 1 
ATOM   940   N  N   . SER A 1 137 ? 133.698 108.005 147.883 1.00 47.06  ?  126 SER A N   1 
ATOM   941   C  CA  . SER A 1 137 ? 133.435 107.483 149.210 1.00 47.06  ?  126 SER A CA  1 
ATOM   942   C  C   . SER A 1 137 ? 133.297 108.663 150.158 1.00 47.06  ?  126 SER A C   1 
ATOM   943   O  O   . SER A 1 137 ? 134.269 109.381 150.401 1.00 47.06  ?  126 SER A O   1 
ATOM   944   C  CB  . SER A 1 137 ? 134.553 106.548 149.653 1.00 47.06  ?  126 SER A CB  1 
ATOM   945   O  OG  . SER A 1 137 ? 134.492 106.324 151.041 1.00 47.06  ?  126 SER A OG  1 
ATOM   946   N  N   . VAL A 1 138 ? 132.100 108.868 150.677 1.00 45.73  ?  127 VAL A N   1 
ATOM   947   C  CA  . VAL A 1 138 ? 131.777 110.059 151.448 1.00 45.73  ?  127 VAL A CA  1 
ATOM   948   C  C   . VAL A 1 138 ? 132.168 109.846 152.901 1.00 45.73  ?  127 VAL A C   1 
ATOM   949   O  O   . VAL A 1 138 ? 131.864 108.809 153.497 1.00 45.73  ?  127 VAL A O   1 
ATOM   950   C  CB  . VAL A 1 138 ? 130.287 110.410 151.309 1.00 45.73  ?  127 VAL A CB  1 
ATOM   951   C  CG1 . VAL A 1 138 ? 129.937 111.594 152.167 1.00 45.73  ?  127 VAL A CG1 1 
ATOM   952   C  CG2 . VAL A 1 138 ? 129.974 110.712 149.872 1.00 45.73  ?  127 VAL A CG2 1 
ATOM   953   N  N   . GLY A 1 139 ? 132.850 110.831 153.469 1.00 45.17  ?  128 GLY A N   1 
ATOM   954   C  CA  . GLY A 1 139 ? 133.353 110.748 154.813 1.00 45.17  ?  128 GLY A CA  1 
ATOM   955   C  C   . GLY A 1 139 ? 134.436 111.775 155.042 1.00 45.17  ?  128 GLY A C   1 
ATOM   956   O  O   . GLY A 1 139 ? 134.618 112.697 154.248 1.00 45.17  ?  128 GLY A O   1 
ATOM   957   N  N   . PRO A 1 140 ? 135.188 111.630 156.123 1.00 45.27  ?  129 PRO A N   1 
ATOM   958   C  CA  . PRO A 1 140 ? 136.211 112.622 156.459 1.00 45.27  ?  129 PRO A CA  1 
ATOM   959   C  C   . PRO A 1 140 ? 137.482 112.468 155.634 1.00 45.27  ?  129 PRO A C   1 
ATOM   960   O  O   . PRO A 1 140 ? 137.784 111.408 155.091 1.00 45.27  ?  129 PRO A O   1 
ATOM   961   C  CB  . PRO A 1 140 ? 136.480 112.339 157.942 1.00 45.27  ?  129 PRO A CB  1 
ATOM   962   C  CG  . PRO A 1 140 ? 136.140 110.919 158.120 1.00 45.27  ?  129 PRO A CG  1 
ATOM   963   C  CD  . PRO A 1 140 ? 135.084 110.567 157.132 1.00 45.27  ?  129 PRO A CD  1 
ATOM   964   N  N   . PHE A 1 141 ? 138.218 113.564 155.534 1.00 44.75  ?  130 PHE A N   1 
ATOM   965   C  CA  . PHE A 1 141 ? 139.541 113.570 154.931 1.00 44.75  ?  130 PHE A CA  1 
ATOM   966   C  C   . PHE A 1 141 ? 140.427 114.514 155.722 1.00 44.75  ?  130 PHE A C   1 
ATOM   967   O  O   . PHE A 1 141 ? 139.927 115.340 156.494 1.00 44.75  ?  130 PHE A O   1 
ATOM   968   C  CB  . PHE A 1 141 ? 139.488 113.933 153.436 1.00 44.75  ?  130 PHE A CB  1 
ATOM   969   C  CG  . PHE A 1 141 ? 138.955 115.297 153.126 1.00 44.75  ?  130 PHE A CG  1 
ATOM   970   C  CD1 . PHE A 1 141 ? 139.806 116.298 152.708 1.00 44.75  ?  130 PHE A CD1 1 
ATOM   971   C  CD2 . PHE A 1 141 ? 137.603 115.560 153.175 1.00 44.75  ?  130 PHE A CD2 1 
ATOM   972   C  CE1 . PHE A 1 141 ? 139.333 117.541 152.392 1.00 44.75  ?  130 PHE A CE1 1 
ATOM   973   C  CE2 . PHE A 1 141 ? 137.124 116.806 152.854 1.00 44.75  ?  130 PHE A CE2 1 
ATOM   974   C  CZ  . PHE A 1 141 ? 137.990 117.798 152.462 1.00 44.75  ?  130 PHE A CZ  1 
ATOM   975   N  N   . PRO A 1 142 ? 141.758 114.395 155.594 1.00 46.42  ?  131 PRO A N   1 
ATOM   976   C  CA  . PRO A 1 142 ? 142.651 115.067 156.556 1.00 46.42  ?  131 PRO A CA  1 
ATOM   977   C  C   . PRO A 1 142 ? 142.574 116.583 156.569 1.00 46.42  ?  131 PRO A C   1 
ATOM   978   O  O   . PRO A 1 142 ? 142.622 117.184 157.648 1.00 46.42  ?  131 PRO A O   1 
ATOM   979   C  CB  . PRO A 1 142 ? 144.039 114.591 156.118 1.00 46.42  ?  131 PRO A CB  1 
ATOM   980   C  CG  . PRO A 1 142 ? 143.803 113.358 155.402 1.00 46.42  ?  131 PRO A CG  1 
ATOM   981   C  CD  . PRO A 1 142 ? 142.517 113.508 154.699 1.00 46.42  ?  131 PRO A CD  1 
ATOM   982   N  N   . ILE A 1 143 ? 142.485 117.224 155.407 1.00 47.70  ?  132 ILE A N   1 
ATOM   983   C  CA  . ILE A 1 143 ? 142.471 118.682 155.375 1.00 47.70  ?  132 ILE A CA  1 
ATOM   984   C  C   . ILE A 1 143 ? 141.248 119.219 156.099 1.00 47.70  ?  132 ILE A C   1 
ATOM   985   O  O   . ILE A 1 143 ? 141.338 120.169 156.887 1.00 47.70  ?  132 ILE A O   1 
ATOM   986   C  CB  . ILE A 1 143 ? 142.540 119.184 153.924 1.00 47.70  ?  132 ILE A CB  1 
ATOM   987   C  CG1 . ILE A 1 143 ? 143.909 118.878 153.328 1.00 47.70  ?  132 ILE A CG1 1 
ATOM   988   C  CG2 . ILE A 1 143 ? 142.260 120.667 153.855 1.00 47.70  ?  132 ILE A CG2 1 
ATOM   989   C  CD1 . ILE A 1 143 ? 143.978 119.104 151.845 1.00 47.70  ?  132 ILE A CD1 1 
ATOM   990   N  N   . LEU A 1 144 ? 140.089 118.607 155.867 1.00 45.73  ?  133 LEU A N   1 
ATOM   991   C  CA  . LEU A 1 144 ? 138.884 119.075 156.529 1.00 45.73  ?  133 LEU A CA  1 
ATOM   992   C  C   . LEU A 1 144 ? 138.902 118.777 158.015 1.00 45.73  ?  133 LEU A C   1 
ATOM   993   O  O   . LEU A 1 144 ? 138.366 119.557 158.798 1.00 45.73  ?  133 LEU A O   1 
ATOM   994   C  CB  . LEU A 1 144 ? 137.649 118.462 155.888 1.00 45.73  ?  133 LEU A CB  1 
ATOM   995   C  CG  . LEU A 1 144 ? 136.441 119.387 155.947 1.00 45.73  ?  133 LEU A CG  1 
ATOM   996   C  CD1 . LEU A 1 144 ? 136.706 120.633 155.135 1.00 45.73  ?  133 LEU A CD1 1 
ATOM   997   C  CD2 . LEU A 1 144 ? 135.229 118.676 155.453 1.00 45.73  ?  133 LEU A CD2 1 
ATOM   998   N  N   . SER A 1 145 ? 139.498 117.662 158.425 1.00 46.56  ?  134 SER A N   1 
ATOM   999   C  CA  . SER A 1 145 ? 139.595 117.374 159.849 1.00 46.56  ?  134 SER A CA  1 
ATOM   1000  C  C   . SER A 1 145 ? 140.489 118.384 160.550 1.00 46.56  ?  134 SER A C   1 
ATOM   1001  O  O   . SER A 1 145 ? 140.184 118.826 161.662 1.00 46.56  ?  134 SER A O   1 
ATOM   1002  C  CB  . SER A 1 145 ? 140.105 115.957 160.060 1.00 46.56  ?  134 SER A CB  1 
ATOM   1003  O  OG  . SER A 1 145 ? 139.501 115.078 159.140 1.00 46.56  ?  134 SER A OG  1 
ATOM   1004  N  N   . MET A 1 146 ? 141.584 118.785 159.903 1.00 49.36  ?  135 MET A N   1 
ATOM   1005  C  CA  . MET A 1 146 ? 142.416 119.840 160.464 1.00 49.36  ?  135 MET A CA  1 
ATOM   1006  C  C   . MET A 1 146 ? 141.663 121.160 160.548 1.00 49.36  ?  135 MET A C   1 
ATOM   1007  O  O   . MET A 1 146 ? 141.766 121.881 161.545 1.00 49.36  ?  135 MET A O   1 
ATOM   1008  C  CB  . MET A 1 146 ? 143.674 120.003 159.629 1.00 49.36  ?  135 MET A CB  1 
ATOM   1009  C  CG  . MET A 1 146 ? 144.686 118.917 159.829 1.00 49.36  ?  135 MET A CG  1 
ATOM   1010  S  SD  . MET A 1 146 ? 146.293 119.502 159.333 1.00 49.36  ?  135 MET A SD  1 
ATOM   1011  C  CE  . MET A 1 146 ? 146.358 121.029 160.249 1.00 49.36  ?  135 MET A CE  1 
ATOM   1012  N  N   . MET A 1 147 ? 140.912 121.503 159.502 1.00 49.58  ?  136 MET A N   1 
ATOM   1013  C  CA  . MET A 1 147 ? 140.144 122.743 159.526 1.00 49.58  ?  136 MET A CA  1 
ATOM   1014  C  C   . MET A 1 147 ? 139.086 122.724 160.623 1.00 49.58  ?  136 MET A C   1 
ATOM   1015  O  O   . MET A 1 147 ? 138.871 123.732 161.303 1.00 49.58  ?  136 MET A O   1 
ATOM   1016  C  CB  . MET A 1 147 ? 139.504 122.984 158.166 1.00 49.58  ?  136 MET A CB  1 
ATOM   1017  C  CG  . MET A 1 147 ? 140.500 123.260 157.070 1.00 49.58  ?  136 MET A CG  1 
ATOM   1018  S  SD  . MET A 1 147 ? 139.743 123.572 155.478 1.00 49.58  ?  136 MET A SD  1 
ATOM   1019  C  CE  . MET A 1 147 ? 139.100 125.210 155.734 1.00 49.58  ?  136 MET A CE  1 
ATOM   1020  N  N   . VAL A 1 148 ? 138.416 121.590 160.810 1.00 49.63  ?  137 VAL A N   1 
ATOM   1021  C  CA  . VAL A 1 148 ? 137.421 121.480 161.868 1.00 49.63  ?  137 VAL A CA  1 
ATOM   1022  C  C   . VAL A 1 148 ? 138.081 121.574 163.234 1.00 49.63  ?  137 VAL A C   1 
ATOM   1023  O  O   . VAL A 1 148 ? 137.549 122.207 164.147 1.00 49.63  ?  137 VAL A O   1 
ATOM   1024  C  CB  . VAL A 1 148 ? 136.611 120.178 161.716 1.00 49.63  ?  137 VAL A CB  1 
ATOM   1025  C  CG1 . VAL A 1 148 ? 135.739 119.943 162.924 1.00 49.63  ?  137 VAL A CG1 1 
ATOM   1026  C  CG2 . VAL A 1 148 ? 135.761 120.230 160.479 1.00 49.63  ?  137 VAL A CG2 1 
ATOM   1027  N  N   . GLY A 1 149 ? 139.248 120.952 163.403 1.00 50.72  ?  138 GLY A N   1 
ATOM   1028  C  CA  . GLY A 1 149 ? 139.949 121.058 164.670 1.00 50.72  ?  138 GLY A CA  1 
ATOM   1029  C  C   . GLY A 1 149 ? 140.366 122.479 164.996 1.00 50.72  ?  138 GLY A C   1 
ATOM   1030  O  O   . GLY A 1 149 ? 140.285 122.912 166.147 1.00 50.72  ?  138 GLY A O   1 
ATOM   1031  N  N   . LEU A 1 150 ? 140.809 123.227 163.988 1.00 52.01  ?  139 LEU A N   1 
ATOM   1032  C  CA  . LEU A 1 150 ? 141.154 124.626 164.214 1.00 52.01  ?  139 LEU A CA  1 
ATOM   1033  C  C   . LEU A 1 150 ? 139.919 125.461 164.531 1.00 52.01  ?  139 LEU A C   1 
ATOM   1034  O  O   . LEU A 1 150 ? 139.961 126.332 165.410 1.00 52.01  ?  139 LEU A O   1 
ATOM   1035  C  CB  . LEU A 1 150 ? 141.887 125.186 163.000 1.00 52.01  ?  139 LEU A CB  1 
ATOM   1036  C  CG  . LEU A 1 150 ? 143.318 124.686 162.832 1.00 52.01  ?  139 LEU A CG  1 
ATOM   1037  C  CD1 . LEU A 1 150 ? 143.749 124.753 161.383 1.00 52.01  ?  139 LEU A CD1 1 
ATOM   1038  C  CD2 . LEU A 1 150 ? 144.255 125.478 163.707 1.00 52.01  ?  139 LEU A CD2 1 
ATOM   1039  N  N   . ALA A 1 151 ? 138.814 125.218 163.826 1.00 52.29  ?  140 ALA A N   1 
ATOM   1040  C  CA  . ALA A 1 151 ? 137.571 125.913 164.139 1.00 52.29  ?  140 ALA A CA  1 
ATOM   1041  C  C   . ALA A 1 151 ? 137.122 125.624 165.562 1.00 52.29  ?  140 ALA A C   1 
ATOM   1042  O  O   . ALA A 1 151 ? 136.630 126.513 166.259 1.00 52.29  ?  140 ALA A O   1 
ATOM   1043  C  CB  . ALA A 1 151 ? 136.482 125.517 163.148 1.00 52.29  ?  140 ALA A CB  1 
ATOM   1044  N  N   . VAL A 1 152 ? 137.317 124.404 166.036 1.00 54.84  ?  141 VAL A N   1 
ATOM   1045  C  CA  . VAL A 1 152 ? 136.925 124.048 167.397 1.00 54.84  ?  141 VAL A CA  1 
ATOM   1046  C  C   . VAL A 1 152 ? 137.771 124.766 168.438 1.00 54.84  ?  141 VAL A C   1 
ATOM   1047  O  O   . VAL A 1 152 ? 137.249 125.261 169.429 1.00 54.84  ?  141 VAL A O   1 
ATOM   1048  C  CB  . VAL A 1 152 ? 137.007 122.526 167.632 1.00 54.84  ?  141 VAL A CB  1 
ATOM   1049  C  CG1 . VAL A 1 152 ? 136.810 122.200 169.103 1.00 54.84  ?  141 VAL A CG1 1 
ATOM   1050  C  CG2 . VAL A 1 152 ? 135.976 121.807 166.780 1.00 54.84  ?  141 VAL A CG2 1 
ATOM   1051  N  N   . SER A 1 153 ? 139.074 124.832 168.213 1.00 58.25  ?  142 SER A N   1 
ATOM   1052  C  CA  . SER A 1 153 ? 139.964 125.497 169.153 1.00 58.25  ?  142 SER A CA  1 
ATOM   1053  C  C   . SER A 1 153 ? 139.562 126.953 169.317 1.00 58.25  ?  142 SER A C   1 
ATOM   1054  O  O   . SER A 1 153 ? 139.503 127.463 170.432 1.00 58.25  ?  142 SER A O   1 
ATOM   1055  C  CB  . SER A 1 153 ? 141.411 125.377 168.687 1.00 58.25  ?  142 SER A CB  1 
ATOM   1056  O  OG  . SER A 1 153 ? 141.826 124.024 168.674 1.00 58.25  ?  142 SER A OG  1 
ATOM   1057  N  N   . GLY A 1 154 ? 139.259 127.619 168.214 1.00 61.28  ?  143 GLY A N   1 
ATOM   1058  C  CA  . GLY A 1 154 ? 138.811 128.992 168.284 1.00 61.28  ?  143 GLY A CA  1 
ATOM   1059  C  C   . GLY A 1 154 ? 137.478 129.150 168.981 1.00 61.28  ?  143 GLY A C   1 
ATOM   1060  O  O   . GLY A 1 154 ? 137.300 130.052 169.791 1.00 61.28  ?  143 GLY A O   1 
ATOM   1061  N  N   . ALA A 1 155 ? 136.535 128.271 168.682 1.00 61.88  ?  144 ALA A N   1 
ATOM   1062  C  CA  . ALA A 1 155 ? 135.225 128.345 169.303 1.00 61.88  ?  144 ALA A CA  1 
ATOM   1063  C  C   . ALA A 1 155 ? 135.335 128.209 170.807 1.00 61.88  ?  144 ALA A C   1 
ATOM   1064  O  O   . ALA A 1 155 ? 134.691 128.942 171.548 1.00 61.88  ?  144 ALA A O   1 
ATOM   1065  C  CB  . ALA A 1 155 ? 134.315 127.269 168.744 1.00 61.88  ?  144 ALA A CB  1 
ATOM   1066  N  N   . VAL A 1 156 ? 136.149 127.269 171.260 1.00 64.76  ?  145 VAL A N   1 
ATOM   1067  C  CA  . VAL A 1 156 ? 136.305 127.049 172.688 1.00 64.76  ?  145 VAL A CA  1 
ATOM   1068  C  C   . VAL A 1 156 ? 136.965 128.248 173.346 1.00 64.76  ?  145 VAL A C   1 
ATOM   1069  O  O   . VAL A 1 156 ? 136.569 128.665 174.432 1.00 64.76  ?  145 VAL A O   1 
ATOM   1070  C  CB  . VAL A 1 156 ? 137.134 125.785 172.967 1.00 64.76  ?  145 VAL A CB  1 
ATOM   1071  C  CG1 . VAL A 1 156 ? 137.461 125.678 174.447 1.00 64.76  ?  145 VAL A CG1 1 
ATOM   1072  C  CG2 . VAL A 1 156 ? 136.389 124.550 172.485 1.00 64.76  ?  145 VAL A CG2 1 
ATOM   1073  N  N   . SER A 1 157 ? 137.967 128.810 172.686 1.00 66.97  ?  146 SER A N   1 
ATOM   1074  C  CA  . SER A 1 157 ? 138.669 129.956 173.236 1.00 66.97  ?  146 SER A CA  1 
ATOM   1075  C  C   . SER A 1 157 ? 137.755 131.163 173.375 1.00 66.97  ?  146 SER A C   1 
ATOM   1076  O  O   . SER A 1 157 ? 137.932 131.972 174.281 1.00 66.97  ?  146 SER A O   1 
ATOM   1077  C  CB  . SER A 1 157 ? 139.869 130.309 172.355 1.00 66.97  ?  146 SER A CB  1 
ATOM   1078  O  OG  . SER A 1 157 ? 139.457 130.739 171.071 1.00 66.97  ?  146 SER A OG  1 
ATOM   1079  N  N   . LYS A 1 158 ? 136.783 131.296 172.484 1.00 69.97  ?  147 LYS A N   1 
ATOM   1080  C  CA  . LYS A 1 158 ? 135.894 132.456 172.512 1.00 69.97  ?  147 LYS A CA  1 
ATOM   1081  C  C   . LYS A 1 158 ? 134.648 132.242 173.358 1.00 69.97  ?  147 LYS A C   1 
ATOM   1082  O  O   . LYS A 1 158 ? 133.780 133.109 173.408 1.00 69.97  ?  147 LYS A O   1 
ATOM   1083  C  CB  . LYS A 1 158 ? 135.469 132.821 171.092 1.00 69.97  ?  147 LYS A CB  1 
ATOM   1084  C  CG  . LYS A 1 158 ? 136.623 133.051 170.136 1.00 69.97  ?  147 LYS A CG  1 
ATOM   1085  C  CD  . LYS A 1 158 ? 136.111 133.173 168.712 1.00 69.97  ?  147 LYS A CD  1 
ATOM   1086  C  CE  . LYS A 1 158 ? 137.254 133.262 167.717 1.00 69.97  ?  147 LYS A CE  1 
ATOM   1087  N  NZ  . LYS A 1 158 ? 136.745 133.331 166.320 1.00 69.97  1  147 LYS A NZ  1 
ATOM   1088  N  N   . ALA A 1 159 ? 134.553 131.102 174.028 1.00 73.97  ?  148 ALA A N   1 
ATOM   1089  C  CA  . ALA A 1 159 ? 133.354 130.797 174.807 1.00 73.97  ?  148 ALA A CA  1 
ATOM   1090  C  C   . ALA A 1 159 ? 133.350 131.436 176.187 1.00 73.97  ?  148 ALA A C   1 
ATOM   1091  O  O   . ALA A 1 159 ? 134.086 131.002 177.072 1.00 73.97  ?  148 ALA A O   1 
ATOM   1092  C  CB  . ALA A 1 159 ? 133.187 129.295 174.941 1.00 73.97  ?  148 ALA A CB  1 
ATOM   1093  N  N   . VAL A 1 160 ? 132.526 132.460 176.381 1.00 80.22  ?  149 VAL A N   1 
ATOM   1094  C  CA  . VAL A 1 160 ? 132.393 133.089 177.691 1.00 80.22  ?  149 VAL A CA  1 
ATOM   1095  C  C   . VAL A 1 160 ? 132.138 132.002 178.728 1.00 80.22  ?  149 VAL A C   1 
ATOM   1096  O  O   . VAL A 1 160 ? 131.374 131.061 178.472 1.00 80.22  ?  149 VAL A O   1 
ATOM   1097  C  CB  . VAL A 1 160 ? 131.290 134.162 177.689 1.00 80.22  ?  149 VAL A CB  1 
ATOM   1098  C  CG1 . VAL A 1 160 ? 131.539 135.167 176.578 1.00 80.22  ?  149 VAL A CG1 1 
ATOM   1099  C  CG2 . VAL A 1 160 ? 129.914 133.538 177.522 1.00 80.22  ?  149 VAL A CG2 1 
ATOM   1100  N  N   . PRO A 1 161 ? 132.785 132.066 179.898 1.00 82.01  ?  150 PRO A N   1 
ATOM   1101  C  CA  . PRO A 1 161 ? 132.621 131.049 180.939 1.00 82.01  ?  150 PRO A CA  1 
ATOM   1102  C  C   . PRO A 1 161 ? 131.249 131.115 181.597 1.00 82.01  ?  150 PRO A C   1 
ATOM   1103  O  O   . PRO A 1 161 ? 130.535 132.089 181.367 1.00 82.01  ?  150 PRO A O   1 
ATOM   1104  C  CB  . PRO A 1 161 ? 133.730 131.389 181.943 1.00 82.01  ?  150 PRO A CB  1 
ATOM   1105  C  CG  . PRO A 1 161 ? 134.676 132.279 181.199 1.00 82.01  ?  150 PRO A CG  1 
ATOM   1106  C  CD  . PRO A 1 161 ? 133.825 133.044 180.248 1.00 82.01  ?  150 PRO A CD  1 
ATOM   1107  N  N   . LEU A 1 179 ? 139.713 116.804 181.639 1.00 84.47  ?  168 LEU A N   1 
ATOM   1108  C  CA  . LEU A 1 179 ? 140.015 115.914 180.524 1.00 84.47  ?  168 LEU A CA  1 
ATOM   1109  C  C   . LEU A 1 179 ? 138.754 115.535 179.775 1.00 84.47  ?  168 LEU A C   1 
ATOM   1110  O  O   . LEU A 1 179 ? 138.560 115.942 178.633 1.00 84.47  ?  168 LEU A O   1 
ATOM   1111  C  CB  . LEU A 1 179 ? 140.724 114.651 181.010 1.00 84.47  ?  168 LEU A CB  1 
ATOM   1112  C  CG  . LEU A 1 179 ? 142.225 114.756 181.286 1.00 84.47  ?  168 LEU A CG  1 
ATOM   1113  C  CD1 . LEU A 1 179 ? 142.963 115.180 180.027 1.00 84.47  ?  168 LEU A CD1 1 
ATOM   1114  C  CD2 . LEU A 1 179 ? 142.516 115.712 182.432 1.00 84.47  ?  168 LEU A CD2 1 
ATOM   1115  N  N   . LEU A 1 180 ? 137.897 114.751 180.413 1.00 83.84  ?  169 LEU A N   1 
ATOM   1116  C  CA  . LEU A 1 180 ? 136.641 114.373 179.788 1.00 83.84  ?  169 LEU A CA  1 
ATOM   1117  C  C   . LEU A 1 180 ? 135.793 115.605 179.543 1.00 83.84  ?  169 LEU A C   1 
ATOM   1118  O  O   . LEU A 1 180 ? 135.101 115.693 178.532 1.00 83.84  ?  169 LEU A O   1 
ATOM   1119  C  CB  . LEU A 1 180 ? 135.881 113.374 180.655 1.00 83.84  ?  169 LEU A CB  1 
ATOM   1120  C  CG  . LEU A 1 180 ? 134.541 112.922 180.072 1.00 83.84  ?  169 LEU A CG  1 
ATOM   1121  C  CD1 . LEU A 1 180 ? 134.732 112.340 178.680 1.00 83.84  ?  169 LEU A CD1 1 
ATOM   1122  C  CD2 . LEU A 1 180 ? 133.854 111.923 180.989 1.00 83.84  ?  169 LEU A CD2 1 
ATOM   1123  N  N   . ASP A 1 181 ? 135.841 116.561 180.460 1.00 82.76  ?  170 ASP A N   1 
ATOM   1124  C  CA  . ASP A 1 181 ? 135.102 117.796 180.265 1.00 82.76  ?  170 ASP A CA  1 
ATOM   1125  C  C   . ASP A 1 181 ? 135.593 118.508 179.024 1.00 82.76  ?  170 ASP A C   1 
ATOM   1126  O  O   . ASP A 1 181 ? 134.791 118.983 178.220 1.00 82.76  ?  170 ASP A O   1 
ATOM   1127  C  CB  . ASP A 1 181 ? 135.254 118.709 181.477 1.00 82.76  ?  170 ASP A CB  1 
ATOM   1128  C  CG  . ASP A 1 181 ? 134.529 118.182 182.694 1.00 82.76  ?  170 ASP A CG  1 
ATOM   1129  O  OD1 . ASP A 1 181 ? 134.804 118.674 183.808 1.00 82.76  ?  170 ASP A OD1 1 
ATOM   1130  O  OD2 . ASP A 1 181 ? 133.685 117.274 182.538 1.00 82.76  -1 170 ASP A OD2 1 
ATOM   1131  N  N   . ASP A 1 182 ? 136.907 118.583 178.860 1.00 79.05  ?  171 ASP A N   1 
ATOM   1132  C  CA  . ASP A 1 182 ? 137.472 119.233 177.685 1.00 79.05  ?  171 ASP A CA  1 
ATOM   1133  C  C   . ASP A 1 182 ? 137.057 118.490 176.430 1.00 79.05  ?  171 ASP A C   1 
ATOM   1134  O  O   . ASP A 1 182 ? 136.717 119.108 175.424 1.00 79.05  ?  171 ASP A O   1 
ATOM   1135  C  CB  . ASP A 1 182 ? 138.992 119.296 177.784 1.00 79.05  ?  171 ASP A CB  1 
ATOM   1136  C  CG  . ASP A 1 182 ? 139.464 120.027 179.023 1.00 79.05  ?  171 ASP A CG  1 
ATOM   1137  O  OD1 . ASP A 1 182 ? 140.690 120.078 179.254 1.00 79.05  ?  171 ASP A OD1 1 
ATOM   1138  O  OD2 . ASP A 1 182 ? 138.609 120.551 179.768 1.00 79.05  -1 171 ASP A OD2 1 
ATOM   1139  N  N   . GLU A 1 183 ? 137.072 117.163 176.488 1.00 74.71  ?  172 GLU A N   1 
ATOM   1140  C  CA  . GLU A 1 183 ? 136.650 116.368 175.349 1.00 74.71  ?  172 GLU A CA  1 
ATOM   1141  C  C   . GLU A 1 183 ? 135.193 116.635 175.033 1.00 74.71  ?  172 GLU A C   1 
ATOM   1142  O  O   . GLU A 1 183 ? 134.824 116.758 173.874 1.00 74.71  ?  172 GLU A O   1 
ATOM   1143  C  CB  . GLU A 1 183 ? 136.863 114.887 175.628 1.00 74.71  ?  172 GLU A CB  1 
ATOM   1144  C  CG  . GLU A 1 183 ? 138.323 114.475 175.661 1.00 74.71  ?  172 GLU A CG  1 
ATOM   1145  C  CD  . GLU A 1 183 ? 138.504 113.005 175.975 1.00 74.71  ?  172 GLU A CD  1 
ATOM   1146  O  OE1 . GLU A 1 183 ? 139.637 112.502 175.832 1.00 74.71  ?  172 GLU A OE1 1 
ATOM   1147  O  OE2 . GLU A 1 183 ? 137.512 112.353 176.360 1.00 74.71  -1 172 GLU A OE2 1 
ATOM   1148  N  N   . ARG A 1 184 ? 134.367 116.743 176.060 1.00 72.90  ?  173 ARG A N   1 
ATOM   1149  C  CA  . ARG A 1 184 ? 132.952 117.016 175.859 1.00 72.90  ?  173 ARG A CA  1 
ATOM   1150  C  C   . ARG A 1 184 ? 132.746 118.329 175.128 1.00 72.90  ?  173 ARG A C   1 
ATOM   1151  O  O   . ARG A 1 184 ? 131.944 118.409 174.202 1.00 72.90  ?  173 ARG A O   1 
ATOM   1152  C  CB  . ARG A 1 184 ? 132.243 117.046 177.204 1.00 72.90  ?  173 ARG A CB  1 
ATOM   1153  C  CG  . ARG A 1 184 ? 130.839 117.616 177.170 1.00 72.90  ?  173 ARG A CG  1 
ATOM   1154  C  CD  . ARG A 1 184 ? 130.330 117.828 178.584 1.00 72.90  ?  173 ARG A CD  1 
ATOM   1155  N  NE  . ARG A 1 184 ? 131.346 118.457 179.422 1.00 72.90  ?  173 ARG A NE  1 
ATOM   1156  C  CZ  . ARG A 1 184 ? 131.554 119.768 179.486 1.00 72.90  ?  173 ARG A CZ  1 
ATOM   1157  N  NH1 . ARG A 1 184 ? 132.503 120.253 180.274 1.00 72.90  1  173 ARG A NH1 1 
ATOM   1158  N  NH2 . ARG A 1 184 ? 130.815 120.593 178.758 1.00 72.90  ?  173 ARG A NH2 1 
ATOM   1159  N  N   . VAL A 1 185 ? 133.482 119.355 175.524 1.00 66.71  ?  174 VAL A N   1 
ATOM   1160  C  CA  . VAL A 1 185 ? 133.331 120.661 174.903 1.00 66.71  ?  174 VAL A CA  1 
ATOM   1161  C  C   . VAL A 1 185 ? 133.789 120.629 173.459 1.00 66.71  ?  174 VAL A C   1 
ATOM   1162  O  O   . VAL A 1 185 ? 133.143 121.203 172.588 1.00 66.71  ?  174 VAL A O   1 
ATOM   1163  C  CB  . VAL A 1 185 ? 134.122 121.741 175.668 1.00 66.71  ?  174 VAL A CB  1 
ATOM   1164  C  CG1 . VAL A 1 185 ? 133.979 123.092 174.989 1.00 66.71  ?  174 VAL A CG1 1 
ATOM   1165  C  CG2 . VAL A 1 185 ? 133.652 121.811 177.112 1.00 66.71  ?  174 VAL A CG2 1 
ATOM   1166  N  N   . ARG A 1 186 ? 134.906 119.961 173.202 1.00 59.09  ?  175 ARG A N   1 
ATOM   1167  C  CA  . ARG A 1 186 ? 135.417 119.877 171.845 1.00 59.09  ?  175 ARG A CA  1 
ATOM   1168  C  C   . ARG A 1 186 ? 134.463 119.087 170.971 1.00 59.09  ?  175 ARG A C   1 
ATOM   1169  O  O   . ARG A 1 186 ? 134.193 119.470 169.838 1.00 59.09  ?  175 ARG A O   1 
ATOM   1170  C  CB  . ARG A 1 186 ? 136.810 119.249 171.827 1.00 59.09  ?  175 ARG A CB  1 
ATOM   1171  C  CG  . ARG A 1 186 ? 137.905 120.155 172.358 1.00 59.09  ?  175 ARG A CG  1 
ATOM   1172  C  CD  . ARG A 1 186 ? 139.284 119.596 172.048 1.00 59.09  ?  175 ARG A CD  1 
ATOM   1173  N  NE  . ARG A 1 186 ? 139.542 119.528 170.613 1.00 59.09  ?  175 ARG A NE  1 
ATOM   1174  C  CZ  . ARG A 1 186 ? 140.073 120.517 169.901 1.00 59.09  ?  175 ARG A CZ  1 
ATOM   1175  N  NH1 . ARG A 1 186 ? 140.402 121.656 170.489 1.00 59.09  1  175 ARG A NH1 1 
ATOM   1176  N  NH2 . ARG A 1 186 ? 140.272 120.369 168.600 1.00 59.09  ?  175 ARG A NH2 1 
ATOM   1177  N  N   . VAL A 1 187 ? 133.941 117.991 171.501 1.00 57.52  ?  176 VAL A N   1 
ATOM   1178  C  CA  . VAL A 1 187 ? 133.023 117.164 170.739 1.00 57.52  ?  176 VAL A CA  1 
ATOM   1179  C  C   . VAL A 1 187 ? 131.773 117.955 170.414 1.00 57.52  ?  176 VAL A C   1 
ATOM   1180  O  O   . VAL A 1 187 ? 131.212 117.814 169.334 1.00 57.52  ?  176 VAL A O   1 
ATOM   1181  C  CB  . VAL A 1 187 ? 132.664 115.871 171.497 1.00 57.52  ?  176 VAL A CB  1 
ATOM   1182  C  CG1 . VAL A 1 187 ? 131.492 115.168 170.832 1.00 57.52  ?  176 VAL A CG1 1 
ATOM   1183  C  CG2 . VAL A 1 187 ? 133.871 114.950 171.571 1.00 57.52  ?  176 VAL A CG2 1 
ATOM   1184  N  N   . ALA A 1 188 ? 131.340 118.798 171.341 1.00 56.44  ?  177 ALA A N   1 
ATOM   1185  C  CA  . ALA A 1 188 ? 130.159 119.620 171.110 1.00 56.44  ?  177 ALA A CA  1 
ATOM   1186  C  C   . ALA A 1 188 ? 130.436 120.718 170.102 1.00 56.44  ?  177 ALA A C   1 
ATOM   1187  O  O   . ALA A 1 188 ? 129.602 121.004 169.252 1.00 56.44  ?  177 ALA A O   1 
ATOM   1188  C  CB  . ALA A 1 188 ? 129.667 120.211 172.416 1.00 56.44  ?  177 ALA A CB  1 
ATOM   1189  N  N   . ALA A 1 189 ? 131.600 121.346 170.199 1.00 54.88  ?  178 ALA A N   1 
ATOM   1190  C  CA  . ALA A 1 189 ? 131.970 122.380 169.242 1.00 54.88  ?  178 ALA A CA  1 
ATOM   1191  C  C   . ALA A 1 189 ? 132.174 121.802 167.851 1.00 54.88  ?  178 ALA A C   1 
ATOM   1192  O  O   . ALA A 1 189 ? 131.813 122.434 166.855 1.00 54.88  ?  178 ALA A O   1 
ATOM   1193  C  CB  . ALA A 1 189 ? 133.225 123.104 169.715 1.00 54.88  ?  178 ALA A CB  1 
ATOM   1194  N  N   . ALA A 1 190 ? 132.746 120.600 167.757 1.00 52.65  ?  179 ALA A N   1 
ATOM   1195  C  CA  . ALA A 1 190 ? 132.922 119.967 166.456 1.00 52.65  ?  179 ALA A CA  1 
ATOM   1196  C  C   . ALA A 1 190 ? 131.584 119.639 165.818 1.00 52.65  ?  179 ALA A C   1 
ATOM   1197  O  O   . ALA A 1 190 ? 131.390 119.857 164.618 1.00 52.65  ?  179 ALA A O   1 
ATOM   1198  C  CB  . ALA A 1 190 ? 133.770 118.707 166.596 1.00 52.65  ?  179 ALA A CB  1 
ATOM   1199  N  N   . ALA A 1 191 ? 130.645 119.119 166.607 1.00 51.79  ?  180 ALA A N   1 
ATOM   1200  C  CA  . ALA A 1 191 ? 129.321 118.827 166.079 1.00 51.79  ?  180 ALA A CA  1 
ATOM   1201  C  C   . ALA A 1 191 ? 128.618 120.096 165.605 1.00 51.79  ?  180 ALA A C   1 
ATOM   1202  O  O   . ALA A 1 191 ? 127.962 120.096 164.555 1.00 51.79  ?  180 ALA A O   1 
ATOM   1203  C  CB  . ALA A 1 191 ? 128.495 118.108 167.139 1.00 51.79  ?  180 ALA A CB  1 
ATOM   1204  N  N   . SER A 1 192 ? 128.755 121.194 166.351 1.00 54.45  ?  181 SER A N   1 
ATOM   1205  C  CA  . SER A 1 192 ? 128.114 122.437 165.934 1.00 54.45  ?  181 SER A CA  1 
ATOM   1206  C  C   . SER A 1 192 ? 128.748 122.998 164.670 1.00 54.45  ?  181 SER A C   1 
ATOM   1207  O  O   . SER A 1 192 ? 128.042 123.499 163.784 1.00 54.45  ?  181 SER A O   1 
ATOM   1208  C  CB  . SER A 1 192 ? 128.172 123.464 167.057 1.00 54.45  ?  181 SER A CB  1 
ATOM   1209  O  OG  . SER A 1 192 ? 127.510 122.985 168.208 1.00 54.45  ?  181 SER A OG  1 
ATOM   1210  N  N   . VAL A 1 193 ? 130.077 122.949 164.580 1.00 49.65  ?  182 VAL A N   1 
ATOM   1211  C  CA  . VAL A 1 193 ? 130.763 123.400 163.376 1.00 49.65  ?  182 VAL A CA  1 
ATOM   1212  C  C   . VAL A 1 193 ? 130.305 122.587 162.175 1.00 49.65  ?  182 VAL A C   1 
ATOM   1213  O  O   . VAL A 1 193 ? 130.079 123.127 161.086 1.00 49.65  ?  182 VAL A O   1 
ATOM   1214  C  CB  . VAL A 1 193 ? 132.285 123.314 163.579 1.00 49.65  ?  182 VAL A CB  1 
ATOM   1215  C  CG1 . VAL A 1 193 ? 133.009 123.361 162.261 1.00 49.65  ?  182 VAL A CG1 1 
ATOM   1216  C  CG2 . VAL A 1 193 ? 132.756 124.427 164.483 1.00 49.65  ?  182 VAL A CG2 1 
ATOM   1217  N  N   . THR A 1 194 ? 130.136 121.280 162.364 1.00 49.58  ?  183 THR A N   1 
ATOM   1218  C  CA  . THR A 1 194 ? 129.660 120.420 161.290 1.00 49.58  ?  183 THR A CA  1 
ATOM   1219  C  C   . THR A 1 194 ? 128.258 120.801 160.847 1.00 49.58  ?  183 THR A C   1 
ATOM   1220  O  O   . THR A 1 194 ? 127.977 120.870 159.646 1.00 49.58  ?  183 THR A O   1 
ATOM   1221  C  CB  . THR A 1 194 ? 129.695 118.975 161.757 1.00 49.58  ?  183 THR A CB  1 
ATOM   1222  O  OG1 . THR A 1 194 ? 130.973 118.718 162.336 1.00 49.58  ?  183 THR A OG1 1 
ATOM   1223  C  CG2 . THR A 1 194 ? 129.453 118.037 160.614 1.00 49.58  ?  183 THR A CG2 1 
ATOM   1224  N  N   . VAL A 1 195 ? 127.359 121.043 161.801 1.00 49.98  ?  184 VAL A N   1 
ATOM   1225  C  CA  . VAL A 1 195 ? 125.993 121.406 161.437 1.00 49.98  ?  184 VAL A CA  1 
ATOM   1226  C  C   . VAL A 1 195 ? 125.969 122.728 160.681 1.00 49.98  ?  184 VAL A C   1 
ATOM   1227  O  O   . VAL A 1 195 ? 125.242 122.876 159.695 1.00 49.98  ?  184 VAL A O   1 
ATOM   1228  C  CB  . VAL A 1 195 ? 125.090 121.448 162.679 1.00 49.98  ?  184 VAL A CB  1 
ATOM   1229  C  CG1 . VAL A 1 195 ? 123.719 121.936 162.299 1.00 49.98  ?  184 VAL A CG1 1 
ATOM   1230  C  CG2 . VAL A 1 195 ? 124.983 120.087 163.291 1.00 49.98  ?  184 VAL A CG2 1 
ATOM   1231  N  N   . LEU A 1 196 ? 126.765 123.707 161.112 1.00 50.49  ?  185 LEU A N   1 
ATOM   1232  C  CA  . LEU A 1 196 ? 126.739 124.989 160.417 1.00 50.49  ?  185 LEU A CA  1 
ATOM   1233  C  C   . LEU A 1 196 ? 127.354 124.886 159.026 1.00 50.49  ?  185 LEU A C   1 
ATOM   1234  O  O   . LEU A 1 196 ? 126.875 125.523 158.080 1.00 50.49  ?  185 LEU A O   1 
ATOM   1235  C  CB  . LEU A 1 196 ? 127.443 126.058 161.242 1.00 50.49  ?  185 LEU A CB  1 
ATOM   1236  C  CG  . LEU A 1 196 ? 127.361 127.466 160.656 1.00 50.49  ?  185 LEU A CG  1 
ATOM   1237  C  CD1 . LEU A 1 196 ? 125.926 127.860 160.399 1.00 50.49  ?  185 LEU A CD1 1 
ATOM   1238  C  CD2 . LEU A 1 196 ? 128.033 128.459 161.558 1.00 50.49  ?  185 LEU A CD2 1 
ATOM   1239  N  N   . SER A 1 197 ? 128.411 124.087 158.872 1.00 49.42  ?  186 SER A N   1 
ATOM   1240  C  CA  . SER A 1 197 ? 128.970 123.854 157.545 1.00 49.42  ?  186 SER A CA  1 
ATOM   1241  C  C   . SER A 1 197 ? 127.949 123.194 156.632 1.00 49.42  ?  186 SER A C   1 
ATOM   1242  O  O   . SER A 1 197 ? 127.816 123.568 155.463 1.00 49.42  ?  186 SER A O   1 
ATOM   1243  C  CB  . SER A 1 197 ? 130.221 122.990 157.647 1.00 49.42  ?  186 SER A CB  1 
ATOM   1244  O  OG  . SER A 1 197 ? 131.136 123.556 158.554 1.00 49.42  ?  186 SER A OG  1 
ATOM   1245  N  N   . GLY A 1 198 ? 127.211 122.214 157.151 1.00 47.69  ?  187 GLY A N   1 
ATOM   1246  C  CA  . GLY A 1 198 ? 126.181 121.581 156.350 1.00 47.69  ?  187 GLY A CA  1 
ATOM   1247  C  C   . GLY A 1 198 ? 125.061 122.530 155.983 1.00 47.69  ?  187 GLY A C   1 
ATOM   1248  O  O   . GLY A 1 198 ? 124.523 122.465 154.880 1.00 47.69  ?  187 GLY A O   1 
ATOM   1249  N  N   . ILE A 1 199 ? 124.693 123.422 156.901 1.00 47.63  ?  188 ILE A N   1 
ATOM   1250  C  CA  . ILE A 1 199 ? 123.668 124.416 156.606 1.00 47.63  ?  188 ILE A CA  1 
ATOM   1251  C  C   . ILE A 1 199 ? 124.124 125.336 155.485 1.00 47.63  ?  188 ILE A C   1 
ATOM   1252  O  O   . ILE A 1 199 ? 123.355 125.657 154.575 1.00 47.63  ?  188 ILE A O   1 
ATOM   1253  C  CB  . ILE A 1 199 ? 123.310 125.205 157.876 1.00 47.63  ?  188 ILE A CB  1 
ATOM   1254  C  CG1 . ILE A 1 199 ? 122.472 124.352 158.816 1.00 47.63  ?  188 ILE A CG1 1 
ATOM   1255  C  CG2 . ILE A 1 199 ? 122.557 126.461 157.529 1.00 47.63  ?  188 ILE A CG2 1 
ATOM   1256  C  CD1 . ILE A 1 199 ? 122.318 124.946 160.169 1.00 47.63  ?  188 ILE A CD1 1 
ATOM   1257  N  N   . ILE A 1 200 ? 125.383 125.767 155.524 1.00 48.58  ?  189 ILE A N   1 
ATOM   1258  C  CA  . ILE A 1 200 ? 125.897 126.639 154.473 1.00 48.58  ?  189 ILE A CA  1 
ATOM   1259  C  C   . ILE A 1 200 ? 125.928 125.911 153.135 1.00 48.58  ?  189 ILE A C   1 
ATOM   1260  O  O   . ILE A 1 200 ? 125.565 126.476 152.096 1.00 48.58  ?  189 ILE A O   1 
ATOM   1261  C  CB  . ILE A 1 200 ? 127.284 127.177 154.864 1.00 48.58  ?  189 ILE A CB  1 
ATOM   1262  C  CG1 . ILE A 1 200 ? 127.165 128.098 156.071 1.00 48.58  ?  189 ILE A CG1 1 
ATOM   1263  C  CG2 . ILE A 1 200 ? 127.926 127.904 153.708 1.00 48.58  ?  189 ILE A CG2 1 
ATOM   1264  C  CD1 . ILE A 1 200 ? 128.473 128.428 156.704 1.00 48.58  ?  189 ILE A CD1 1 
ATOM   1265  N  N   . GLN A 1 201 ? 126.350 124.646 153.135 1.00 47.94  ?  190 GLN A N   1 
ATOM   1266  C  CA  . GLN A 1 201 ? 126.371 123.874 151.895 1.00 47.94  ?  190 GLN A CA  1 
ATOM   1267  C  C   . GLN A 1 201 ? 124.970 123.689 151.332 1.00 47.94  ?  190 GLN A C   1 
ATOM   1268  O  O   . GLN A 1 201 ? 124.750 123.841 150.127 1.00 47.94  ?  190 GLN A O   1 
ATOM   1269  C  CB  . GLN A 1 201 ? 127.022 122.517 152.134 1.00 47.94  ?  190 GLN A CB  1 
ATOM   1270  C  CG  . GLN A 1 201 ? 128.516 122.544 152.125 1.00 47.94  ?  190 GLN A CG  1 
ATOM   1271  C  CD  . GLN A 1 201 ? 129.116 121.235 152.547 1.00 47.94  ?  190 GLN A CD  1 
ATOM   1272  O  OE1 . GLN A 1 201 ? 128.751 120.677 153.572 1.00 47.94  ?  190 GLN A OE1 1 
ATOM   1273  N  NE2 . GLN A 1 201 ? 130.048 120.737 151.760 1.00 47.94  ?  190 GLN A NE2 1 
ATOM   1274  N  N   . LEU A 1 202 ? 124.011 123.352 152.190 1.00 48.60  ?  191 LEU A N   1 
ATOM   1275  C  CA  . LEU A 1 202 ? 122.640 123.165 151.744 1.00 48.60  ?  191 LEU A CA  1 
ATOM   1276  C  C   . LEU A 1 202 ? 122.055 124.458 151.199 1.00 48.60  ?  191 LEU A C   1 
ATOM   1277  O  O   . LEU A 1 202 ? 121.333 124.445 150.197 1.00 48.60  ?  191 LEU A O   1 
ATOM   1278  C  CB  . LEU A 1 202 ? 121.798 122.636 152.899 1.00 48.60  ?  191 LEU A CB  1 
ATOM   1279  C  CG  . LEU A 1 202 ? 120.317 122.407 152.653 1.00 48.60  ?  191 LEU A CG  1 
ATOM   1280  C  CD1 . LEU A 1 202 ? 120.116 121.345 151.603 1.00 48.60  ?  191 LEU A CD1 1 
ATOM   1281  C  CD2 . LEU A 1 202 ? 119.659 122.006 153.942 1.00 48.60  ?  191 LEU A CD2 1 
ATOM   1282  N  N   . ALA A 1 203 ? 122.355 125.587 151.840 1.00 48.89  ?  192 ALA A N   1 
ATOM   1283  C  CA  . ALA A 1 203 ? 121.872 126.867 151.339 1.00 48.89  ?  192 ALA A CA  1 
ATOM   1284  C  C   . ALA A 1 203 ? 122.455 127.170 149.970 1.00 48.89  ?  192 ALA A C   1 
ATOM   1285  O  O   . ALA A 1 203 ? 121.738 127.586 149.058 1.00 48.89  ?  192 ALA A O   1 
ATOM   1286  C  CB  . ALA A 1 203 ? 122.212 127.979 152.325 1.00 48.89  ?  192 ALA A CB  1 
ATOM   1287  N  N   . PHE A 1 204 ? 123.761 126.959 149.804 1.00 51.03  ?  193 PHE A N   1 
ATOM   1288  C  CA  . PHE A 1 204 ? 124.382 127.188 148.505 1.00 51.03  ?  193 PHE A CA  1 
ATOM   1289  C  C   . PHE A 1 204 ? 123.822 126.264 147.439 1.00 51.03  ?  193 PHE A C   1 
ATOM   1290  O  O   . PHE A 1 204 ? 123.772 126.634 146.265 1.00 51.03  ?  193 PHE A O   1 
ATOM   1291  C  CB  . PHE A 1 204 ? 125.891 127.006 148.608 1.00 51.03  ?  193 PHE A CB  1 
ATOM   1292  C  CG  . PHE A 1 204 ? 126.636 128.277 148.832 1.00 51.03  ?  193 PHE A CG  1 
ATOM   1293  C  CD1 . PHE A 1 204 ? 126.545 128.939 150.039 1.00 51.03  ?  193 PHE A CD1 1 
ATOM   1294  C  CD2 . PHE A 1 204 ? 127.424 128.812 147.837 1.00 51.03  ?  193 PHE A CD2 1 
ATOM   1295  C  CE1 . PHE A 1 204 ? 127.227 130.105 150.251 1.00 51.03  ?  193 PHE A CE1 1 
ATOM   1296  C  CE2 . PHE A 1 204 ? 128.110 129.983 148.044 1.00 51.03  ?  193 PHE A CE2 1 
ATOM   1297  C  CZ  . PHE A 1 204 ? 128.012 130.630 149.255 1.00 51.03  ?  193 PHE A CZ  1 
ATOM   1298  N  N   . GLY A 1 205 ? 123.418 125.053 147.819 1.00 50.43  ?  194 GLY A N   1 
ATOM   1299  C  CA  . GLY A 1 205 ? 122.848 124.137 146.851 1.00 50.43  ?  194 GLY A CA  1 
ATOM   1300  C  C   . GLY A 1 205 ? 121.425 124.463 146.473 1.00 50.43  ?  194 GLY A C   1 
ATOM   1301  O  O   . GLY A 1 205 ? 121.017 124.226 145.335 1.00 50.43  ?  194 GLY A O   1 
ATOM   1302  N  N   . ILE A 1 206 ? 120.650 125.000 147.411 1.00 50.79  ?  195 ILE A N   1 
ATOM   1303  C  CA  . ILE A 1 206 ? 119.285 125.411 147.102 1.00 50.79  ?  195 ILE A CA  1 
ATOM   1304  C  C   . ILE A 1 206 ? 119.289 126.674 146.248 1.00 50.79  ?  195 ILE A C   1 
ATOM   1305  O  O   . ILE A 1 206 ? 118.438 126.848 145.370 1.00 50.79  ?  195 ILE A O   1 
ATOM   1306  C  CB  . ILE A 1 206 ? 118.487 125.593 148.404 1.00 50.79  ?  195 ILE A CB  1 
ATOM   1307  C  CG1 . ILE A 1 206 ? 118.198 124.236 149.038 1.00 50.79  ?  195 ILE A CG1 1 
ATOM   1308  C  CG2 . ILE A 1 206 ? 117.201 126.342 148.156 1.00 50.79  ?  195 ILE A CG2 1 
ATOM   1309  C  CD1 . ILE A 1 206 ? 117.853 124.319 150.495 1.00 50.79  ?  195 ILE A CD1 1 
ATOM   1310  N  N   . LEU A 1 207 ? 120.250 127.565 146.477 1.00 50.37  ?  196 LEU A N   1 
ATOM   1311  C  CA  . LEU A 1 207 ? 120.379 128.785 145.693 1.00 50.37  ?  196 LEU A CA  1 
ATOM   1312  C  C   . LEU A 1 207 ? 121.054 128.567 144.348 1.00 50.37  ?  196 LEU A C   1 
ATOM   1313  O  O   . LEU A 1 207 ? 121.287 129.543 143.634 1.00 50.37  ?  196 LEU A O   1 
ATOM   1314  C  CB  . LEU A 1 207 ? 121.156 129.839 146.477 1.00 50.37  ?  196 LEU A CB  1 
ATOM   1315  C  CG  . LEU A 1 207 ? 120.543 130.334 147.782 1.00 50.37  ?  196 LEU A CG  1 
ATOM   1316  C  CD1 . LEU A 1 207 ? 121.481 131.296 148.466 1.00 50.37  ?  196 LEU A CD1 1 
ATOM   1317  C  CD2 . LEU A 1 207 ? 119.211 130.988 147.525 1.00 50.37  ?  196 LEU A CD2 1 
ATOM   1318  N  N   . ARG A 1 208 ? 121.382 127.325 143.998 1.00 50.33  ?  197 ARG A N   1 
ATOM   1319  C  CA  . ARG A 1 208 ? 121.927 126.961 142.688 1.00 50.33  ?  197 ARG A CA  1 
ATOM   1320  C  C   . ARG A 1 208 ? 123.249 127.671 142.407 1.00 50.33  ?  197 ARG A C   1 
ATOM   1321  O  O   . ARG A 1 208 ? 123.483 128.181 141.312 1.00 50.33  ?  197 ARG A O   1 
ATOM   1322  C  CB  . ARG A 1 208 ? 120.925 127.225 141.559 1.00 50.33  ?  197 ARG A CB  1 
ATOM   1323  C  CG  . ARG A 1 208 ? 119.463 126.972 141.874 1.00 50.33  ?  197 ARG A CG  1 
ATOM   1324  C  CD  . ARG A 1 208 ? 119.222 125.652 142.564 1.00 50.33  ?  197 ARG A CD  1 
ATOM   1325  N  NE  . ARG A 1 208 ? 119.352 124.505 141.684 1.00 50.33  ?  197 ARG A NE  1 
ATOM   1326  C  CZ  . ARG A 1 208 ? 119.334 123.252 142.115 1.00 50.33  ?  197 ARG A CZ  1 
ATOM   1327  N  NH1 . ARG A 1 208 ? 119.196 123.001 143.405 1.00 50.33  1  197 ARG A NH1 1 
ATOM   1328  N  NH2 . ARG A 1 208 ? 119.460 122.254 141.259 1.00 50.33  ?  197 ARG A NH2 1 
ATOM   1329  N  N   . ILE A 1 209 ? 124.142 127.674 143.391 1.00 50.88  ?  198 ILE A N   1 
ATOM   1330  C  CA  . ILE A 1 209 ? 125.445 128.307 143.214 1.00 50.88  ?  198 ILE A CA  1 
ATOM   1331  C  C   . ILE A 1 209 ? 126.563 127.277 143.259 1.00 50.88  ?  198 ILE A C   1 
ATOM   1332  O  O   . ILE A 1 209 ? 127.595 127.509 143.877 1.00 50.88  ?  198 ILE A O   1 
ATOM   1333  C  CB  . ILE A 1 209 ? 125.707 129.374 144.292 1.00 50.88  ?  198 ILE A CB  1 
ATOM   1334  C  CG1 . ILE A 1 209 ? 124.398 130.016 144.746 1.00 50.88  ?  198 ILE A CG1 1 
ATOM   1335  C  CG2 . ILE A 1 209 ? 126.670 130.430 143.773 1.00 50.88  ?  198 ILE A CG2 1 
ATOM   1336  C  CD1 . ILE A 1 209 ? 124.569 130.963 145.911 1.00 50.88  ?  198 ILE A CD1 1 
ATOM   1337  N  N   . GLY A 1 210 ? 126.369 126.146 142.592 1.00 51.30  ?  199 GLY A N   1 
ATOM   1338  C  CA  . GLY A 1 210 ? 127.373 125.100 142.573 1.00 51.30  ?  199 GLY A CA  1 
ATOM   1339  C  C   . GLY A 1 210 ? 128.498 125.393 141.611 1.00 51.30  ?  199 GLY A C   1 
ATOM   1340  O  O   . GLY A 1 210 ? 129.405 124.585 141.452 1.00 51.30  ?  199 GLY A O   1 
ATOM   1341  N  N   . PHE A 1 211 ? 128.449 126.548 140.964 1.00 48.69  ?  200 PHE A N   1 
ATOM   1342  C  CA  . PHE A 1 211 ? 129.484 126.926 140.015 1.00 48.69  ?  200 PHE A CA  1 
ATOM   1343  C  C   . PHE A 1 211 ? 130.611 127.665 140.710 1.00 48.69  ?  200 PHE A C   1 
ATOM   1344  O  O   . PHE A 1 211 ? 131.510 128.171 140.060 1.00 48.69  ?  200 PHE A O   1 
ATOM   1345  C  CB  . PHE A 1 211 ? 128.889 127.795 138.909 1.00 48.69  ?  200 PHE A CB  1 
ATOM   1346  C  CG  . PHE A 1 211 ? 128.277 129.070 139.403 1.00 48.69  ?  200 PHE A CG  1 
ATOM   1347  C  CD1 . PHE A 1 211 ? 126.928 129.133 139.699 1.00 48.69  ?  200 PHE A CD1 1 
ATOM   1348  C  CD2 . PHE A 1 211 ? 129.049 130.207 139.569 1.00 48.69  ?  200 PHE A CD2 1 
ATOM   1349  C  CE1 . PHE A 1 211 ? 126.359 130.305 140.152 1.00 48.69  ?  200 PHE A CE1 1 
ATOM   1350  C  CE2 . PHE A 1 211 ? 128.488 131.381 140.025 1.00 48.69  ?  200 PHE A CE2 1 
ATOM   1351  C  CZ  . PHE A 1 211 ? 127.140 131.431 140.316 1.00 48.69  ?  200 PHE A CZ  1 
ATOM   1352  N  N   . VAL A 1 212 ? 130.564 127.735 142.031 1.00 50.35  ?  201 VAL A N   1 
ATOM   1353  C  CA  . VAL A 1 212 ? 131.595 128.439 142.786 1.00 50.35  ?  201 VAL A CA  1 
ATOM   1354  C  C   . VAL A 1 212 ? 132.954 127.764 142.660 1.00 50.35  ?  201 VAL A C   1 
ATOM   1355  O  O   . VAL A 1 212 ? 133.983 128.407 142.817 1.00 50.35  ?  201 VAL A O   1 
ATOM   1356  C  CB  . VAL A 1 212 ? 131.217 128.558 144.275 1.00 50.35  ?  201 VAL A CB  1 
ATOM   1357  C  CG1 . VAL A 1 212 ? 130.099 129.569 144.455 1.00 50.35  ?  201 VAL A CG1 1 
ATOM   1358  C  CG2 . VAL A 1 212 ? 130.820 127.202 144.836 1.00 50.35  ?  201 VAL A CG2 1 
ATOM   1359  N  N   . VAL A 1 213 ? 132.960 126.472 142.375 1.00 49.50  ?  202 VAL A N   1 
ATOM   1360  C  CA  . VAL A 1 213 ? 134.207 125.735 142.231 1.00 49.50  ?  202 VAL A CA  1 
ATOM   1361  C  C   . VAL A 1 213 ? 135.058 126.252 141.080 1.00 49.50  ?  202 VAL A C   1 
ATOM   1362  O  O   . VAL A 1 213 ? 136.252 125.983 141.027 1.00 49.50  ?  202 VAL A O   1 
ATOM   1363  C  CB  . VAL A 1 213 ? 133.933 124.232 142.020 1.00 49.50  ?  202 VAL A CB  1 
ATOM   1364  C  CG1 . VAL A 1 213 ? 133.601 123.558 143.341 1.00 49.50  ?  202 VAL A CG1 1 
ATOM   1365  C  CG2 . VAL A 1 213 ? 132.816 124.033 141.008 1.00 49.50  ?  202 VAL A CG2 1 
ATOM   1366  N  N   . ILE A 1 214 ? 134.452 126.989 140.159 1.00 47.78  ?  203 ILE A N   1 
ATOM   1367  C  CA  . ILE A 1 214 ? 135.183 127.530 139.020 1.00 47.78  ?  203 ILE A CA  1 
ATOM   1368  C  C   . ILE A 1 214 ? 136.122 128.657 139.423 1.00 47.78  ?  203 ILE A C   1 
ATOM   1369  O  O   . ILE A 1 214 ? 137.036 128.994 138.680 1.00 47.78  ?  203 ILE A O   1 
ATOM   1370  C  CB  . ILE A 1 214 ? 134.227 128.051 137.933 1.00 47.78  ?  203 ILE A CB  1 
ATOM   1371  C  CG1 . ILE A 1 214 ? 133.608 129.383 138.368 1.00 47.78  ?  203 ILE A CG1 1 
ATOM   1372  C  CG2 . ILE A 1 214 ? 133.157 127.016 137.623 1.00 47.78  ?  203 ILE A CG2 1 
ATOM   1373  C  CD1 . ILE A 1 214 ? 132.613 129.949 137.383 1.00 47.78  ?  203 ILE A CD1 1 
ATOM   1374  N  N   . TYR A 1 215 ? 135.913 129.232 140.599 1.00 48.05  ?  204 TYR A N   1 
ATOM   1375  C  CA  . TYR A 1 215 ? 136.744 130.337 141.054 1.00 48.05  ?  204 TYR A CA  1 
ATOM   1376  C  C   . TYR A 1 215 ? 138.068 129.855 141.615 1.00 48.05  ?  204 TYR A C   1 
ATOM   1377  O  O   . TYR A 1 215 ? 138.865 130.653 142.088 1.00 48.05  ?  204 TYR A O   1 
ATOM   1378  C  CB  . TYR A 1 215 ? 136.005 131.162 142.102 1.00 48.05  ?  204 TYR A CB  1 
ATOM   1379  C  CG  . TYR A 1 215 ? 134.706 131.751 141.615 1.00 48.05  ?  204 TYR A CG  1 
ATOM   1380  C  CD1 . TYR A 1 215 ? 133.493 131.298 142.108 1.00 48.05  ?  204 TYR A CD1 1 
ATOM   1381  C  CD2 . TYR A 1 215 ? 134.690 132.757 140.660 1.00 48.05  ?  204 TYR A CD2 1 
ATOM   1382  C  CE1 . TYR A 1 215 ? 132.300 131.833 141.669 1.00 48.05  ?  204 TYR A CE1 1 
ATOM   1383  C  CE2 . TYR A 1 215 ? 133.501 133.298 140.215 1.00 48.05  ?  204 TYR A CE2 1 
ATOM   1384  C  CZ  . TYR A 1 215 ? 132.310 132.831 140.725 1.00 48.05  ?  204 TYR A CZ  1 
ATOM   1385  O  OH  . TYR A 1 215 ? 131.122 133.361 140.291 1.00 48.05  ?  204 TYR A OH  1 
ATOM   1386  N  N   . LEU A 1 216 ? 138.307 128.553 141.568 1.00 47.53  ?  205 LEU A N   1 
ATOM   1387  C  CA  . LEU A 1 216 ? 139.569 128.002 142.043 1.00 47.53  ?  205 LEU A CA  1 
ATOM   1388  C  C   . LEU A 1 216 ? 140.396 127.457 140.894 1.00 47.53  ?  205 LEU A C   1 
ATOM   1389  O  O   . LEU A 1 216 ? 140.009 126.477 140.271 1.00 47.53  ?  205 LEU A O   1 
ATOM   1390  C  CB  . LEU A 1 216 ? 139.304 126.905 143.071 1.00 47.53  ?  205 LEU A CB  1 
ATOM   1391  C  CG  . LEU A 1 216 ? 138.466 127.297 144.288 1.00 47.53  ?  205 LEU A CG  1 
ATOM   1392  C  CD1 . LEU A 1 216 ? 138.289 126.108 145.217 1.00 47.53  ?  205 LEU A CD1 1 
ATOM   1393  C  CD2 . LEU A 1 216 ? 139.100 128.463 145.026 1.00 47.53  ?  205 LEU A CD2 1 
ATOM   1394  N  N   . SER A 1 217 ? 141.534 128.080 140.617 1.00 45.65  ?  206 SER A N   1 
ATOM   1395  C  CA  . SER A 1 217 ? 142.401 127.641 139.530 1.00 45.65  ?  206 SER A CA  1 
ATOM   1396  C  C   . SER A 1 217 ? 143.170 126.395 139.912 1.00 45.65  ?  206 SER A C   1 
ATOM   1397  O  O   . SER A 1 217 ? 143.211 126.022 141.077 1.00 45.65  ?  206 SER A O   1 
ATOM   1398  C  CB  . SER A 1 217 ? 143.381 128.747 139.147 1.00 45.65  ?  206 SER A CB  1 
ATOM   1399  O  OG  . SER A 1 217 ? 144.187 129.128 140.243 1.00 45.65  ?  206 SER A OG  1 
ATOM   1400  N  N   . GLU A 1 218 ? 143.797 125.753 138.936 1.00 49.37  ?  207 GLU A N   1 
ATOM   1401  C  CA  . GLU A 1 218 ? 144.597 124.579 139.250 1.00 49.37  ?  207 GLU A CA  1 
ATOM   1402  C  C   . GLU A 1 218 ? 145.858 124.946 140.012 1.00 49.37  ?  207 GLU A C   1 
ATOM   1403  O  O   . GLU A 1 218 ? 146.316 124.166 140.847 1.00 49.37  ?  207 GLU A O   1 
ATOM   1404  C  CB  . GLU A 1 218 ? 144.950 123.826 137.972 1.00 49.37  ?  207 GLU A CB  1 
ATOM   1405  C  CG  . GLU A 1 218 ? 143.759 123.235 137.263 1.00 49.37  ?  207 GLU A CG  1 
ATOM   1406  C  CD  . GLU A 1 218 ? 144.092 122.780 135.863 1.00 49.37  ?  207 GLU A CD  1 
ATOM   1407  O  OE1 . GLU A 1 218 ? 143.202 122.223 135.189 1.00 49.37  ?  207 GLU A OE1 1 
ATOM   1408  O  OE2 . GLU A 1 218 ? 145.250 122.980 135.437 1.00 49.37  -1 207 GLU A OE2 1 
ATOM   1409  N  N   . SER A 1 219 ? 146.433 126.116 139.739 1.00 46.63  ?  208 SER A N   1 
ATOM   1410  C  CA  . SER A 1 219 ? 147.610 126.552 140.481 1.00 46.63  ?  208 SER A CA  1 
ATOM   1411  C  C   . SER A 1 219 ? 147.269 126.824 141.934 1.00 46.63  ?  208 SER A C   1 
ATOM   1412  O  O   . SER A 1 219 ? 148.036 126.471 142.836 1.00 46.63  ?  208 SER A O   1 
ATOM   1413  C  CB  . SER A 1 219 ? 148.203 127.799 139.841 1.00 46.63  ?  208 SER A CB  1 
ATOM   1414  O  OG  . SER A 1 219 ? 148.174 127.693 138.440 1.00 46.63  ?  208 SER A OG  1 
ATOM   1415  N  N   . LEU A 1 220 ? 146.123 127.455 142.177 1.00 44.44  ?  209 LEU A N   1 
ATOM   1416  C  CA  . LEU A 1 220 ? 145.680 127.676 143.543 1.00 44.44  ?  209 LEU A CA  1 
ATOM   1417  C  C   . LEU A 1 220 ? 145.465 126.358 144.264 1.00 44.44  ?  209 LEU A C   1 
ATOM   1418  O  O   . LEU A 1 220 ? 145.880 126.201 145.413 1.00 44.44  ?  209 LEU A O   1 
ATOM   1419  C  CB  . LEU A 1 220 ? 144.402 128.508 143.555 1.00 44.44  ?  209 LEU A CB  1 
ATOM   1420  C  CG  . LEU A 1 220 ? 143.870 128.918 144.924 1.00 44.44  ?  209 LEU A CG  1 
ATOM   1421  C  CD1 . LEU A 1 220 ? 143.343 130.315 144.874 1.00 44.44  ?  209 LEU A CD1 1 
ATOM   1422  C  CD2 . LEU A 1 220 ? 142.787 127.979 145.380 1.00 44.44  ?  209 LEU A CD2 1 
ATOM   1423  N  N   . ILE A 1 221 ? 144.819 125.399 143.607 1.00 44.31  ?  210 ILE A N   1 
ATOM   1424  C  CA  . ILE A 1 221 ? 144.547 124.121 144.251 1.00 44.31  ?  210 ILE A CA  1 
ATOM   1425  C  C   . ILE A 1 221 ? 145.845 123.382 144.536 1.00 44.31  ?  210 ILE A C   1 
ATOM   1426  O  O   . ILE A 1 221 ? 146.013 122.793 145.606 1.00 44.31  ?  210 ILE A O   1 
ATOM   1427  C  CB  . ILE A 1 221 ? 143.587 123.287 143.387 1.00 44.31  ?  210 ILE A CB  1 
ATOM   1428  C  CG1 . ILE A 1 221 ? 142.189 123.887 143.437 1.00 44.31  ?  210 ILE A CG1 1 
ATOM   1429  C  CG2 . ILE A 1 221 ? 143.544 121.861 143.863 1.00 44.31  ?  210 ILE A CG2 1 
ATOM   1430  C  CD1 . ILE A 1 221 ? 141.302 123.433 142.323 1.00 44.31  ?  210 ILE A CD1 1 
ATOM   1431  N  N   . SER A 1 222 ? 146.790 123.423 143.602 1.00 44.60  ?  211 SER A N   1 
ATOM   1432  C  CA  . SER A 1 222 ? 148.069 122.754 143.801 1.00 44.60  ?  211 SER A CA  1 
ATOM   1433  C  C   . SER A 1 222 ? 148.837 123.358 144.971 1.00 44.60  ?  211 SER A C   1 
ATOM   1434  O  O   . SER A 1 222 ? 149.322 122.635 145.850 1.00 44.60  ?  211 SER A O   1 
ATOM   1435  C  CB  . SER A 1 222 ? 148.887 122.829 142.517 1.00 44.60  ?  211 SER A CB  1 
ATOM   1436  O  OG  . SER A 1 222 ? 149.909 121.861 142.500 1.00 44.60  ?  211 SER A OG  1 
ATOM   1437  N  N   . GLY A 1 223 ? 148.956 124.686 145.003 1.00 43.60  ?  212 GLY A N   1 
ATOM   1438  C  CA  . GLY A 1 223 ? 149.668 125.323 146.096 1.00 43.60  ?  212 GLY A CA  1 
ATOM   1439  C  C   . GLY A 1 223 ? 148.984 125.116 147.430 1.00 43.60  ?  212 GLY A C   1 
ATOM   1440  O  O   . GLY A 1 223 ? 149.638 124.848 148.441 1.00 43.60  ?  212 GLY A O   1 
ATOM   1441  N  N   . PHE A 1 224 ? 147.655 125.199 147.442 1.00 44.22  ?  213 PHE A N   1 
ATOM   1442  C  CA  . PHE A 1 224 ? 146.908 125.017 148.673 1.00 44.22  ?  213 PHE A CA  1 
ATOM   1443  C  C   . PHE A 1 224 ? 147.043 123.599 149.197 1.00 44.22  ?  213 PHE A C   1 
ATOM   1444  O  O   . PHE A 1 224 ? 147.208 123.398 150.399 1.00 44.22  ?  213 PHE A O   1 
ATOM   1445  C  CB  . PHE A 1 224 ? 145.441 125.371 148.447 1.00 44.22  ?  213 PHE A CB  1 
ATOM   1446  C  CG  . PHE A 1 224 ? 144.565 125.080 149.621 1.00 44.22  ?  213 PHE A CG  1 
ATOM   1447  C  CD1 . PHE A 1 224 ? 144.491 125.961 150.675 1.00 44.22  ?  213 PHE A CD1 1 
ATOM   1448  C  CD2 . PHE A 1 224 ? 143.822 123.919 149.675 1.00 44.22  ?  213 PHE A CD2 1 
ATOM   1449  C  CE1 . PHE A 1 224 ? 143.698 125.689 151.754 1.00 44.22  ?  213 PHE A CE1 1 
ATOM   1450  C  CE2 . PHE A 1 224 ? 143.033 123.647 150.754 1.00 44.22  ?  213 PHE A CE2 1 
ATOM   1451  C  CZ  . PHE A 1 224 ? 142.966 124.533 151.793 1.00 44.22  ?  213 PHE A CZ  1 
ATOM   1452  N  N   . THR A 1 225 ? 146.988 122.601 148.319 1.00 46.22  ?  214 THR A N   1 
ATOM   1453  C  CA  . THR A 1 225 ? 147.065 121.229 148.796 1.00 46.22  ?  214 THR A CA  1 
ATOM   1454  C  C   . THR A 1 225 ? 148.480 120.835 149.186 1.00 46.22  ?  214 THR A C   1 
ATOM   1455  O  O   . THR A 1 225 ? 148.653 120.012 150.084 1.00 46.22  ?  214 THR A O   1 
ATOM   1456  C  CB  . THR A 1 225 ? 146.508 120.258 147.756 1.00 46.22  ?  214 THR A CB  1 
ATOM   1457  O  OG1 . THR A 1 225 ? 147.102 120.512 146.484 1.00 46.22  ?  214 THR A OG1 1 
ATOM   1458  C  CG2 . THR A 1 225 ? 145.016 120.414 147.648 1.00 46.22  ?  214 THR A CG2 1 
ATOM   1459  N  N   . THR A 1 226 ? 149.502 121.433 148.577 1.00 46.74  ?  215 THR A N   1 
ATOM   1460  C  CA  . THR A 1 226 ? 150.857 121.200 149.063 1.00 46.74  ?  215 THR A CA  1 
ATOM   1461  C  C   . THR A 1 226 ? 151.055 121.808 150.449 1.00 46.74  ?  215 THR A C   1 
ATOM   1462  O  O   . THR A 1 226 ? 151.616 121.167 151.350 1.00 46.74  ?  215 THR A O   1 
ATOM   1463  C  CB  . THR A 1 226 ? 151.874 121.759 148.073 1.00 46.74  ?  215 THR A CB  1 
ATOM   1464  O  OG1 . THR A 1 226 ? 151.395 121.557 146.743 1.00 46.74  ?  215 THR A OG1 1 
ATOM   1465  C  CG2 . THR A 1 226 ? 153.195 121.058 148.225 1.00 46.74  ?  215 THR A CG2 1 
ATOM   1466  N  N   . ALA A 1 227 ? 150.587 123.042 150.646 1.00 45.85  ?  216 ALA A N   1 
ATOM   1467  C  CA  . ALA A 1 227 ? 150.698 123.652 151.965 1.00 45.85  ?  216 ALA A CA  1 
ATOM   1468  C  C   . ALA A 1 227 ? 149.877 122.890 152.996 1.00 45.85  ?  216 ALA A C   1 
ATOM   1469  O  O   . ALA A 1 227 ? 150.285 122.757 154.154 1.00 45.85  ?  216 ALA A O   1 
ATOM   1470  C  CB  . ALA A 1 227 ? 150.271 125.112 151.898 1.00 45.85  ?  216 ALA A CB  1 
ATOM   1471  N  N   . ALA A 1 228 ? 148.732 122.353 152.585 1.00 46.53  ?  217 ALA A N   1 
ATOM   1472  C  CA  . ALA A 1 228 ? 147.905 121.572 153.490 1.00 46.53  ?  217 ALA A CA  1 
ATOM   1473  C  C   . ALA A 1 228 ? 148.540 120.233 153.823 1.00 46.53  ?  217 ALA A C   1 
ATOM   1474  O  O   . ALA A 1 228 ? 148.364 119.729 154.931 1.00 46.53  ?  217 ALA A O   1 
ATOM   1475  C  CB  . ALA A 1 228 ? 146.526 121.374 152.879 1.00 46.53  ?  217 ALA A CB  1 
ATOM   1476  N  N   . ALA A 1 229 ? 149.277 119.641 152.885 1.00 47.52  ?  218 ALA A N   1 
ATOM   1477  C  CA  . ALA A 1 229 ? 150.033 118.437 153.200 1.00 47.52  ?  218 ALA A CA  1 
ATOM   1478  C  C   . ALA A 1 229 ? 151.126 118.727 154.216 1.00 47.52  ?  218 ALA A C   1 
ATOM   1479  O  O   . ALA A 1 229 ? 151.393 117.906 155.097 1.00 47.52  ?  218 ALA A O   1 
ATOM   1480  C  CB  . ALA A 1 229 ? 150.628 117.843 151.928 1.00 47.52  ?  218 ALA A CB  1 
ATOM   1481  N  N   . VAL A 1 230 ? 151.774 119.885 154.109 1.00 47.37  ?  219 VAL A N   1 
ATOM   1482  C  CA  . VAL A 1 230 ? 152.754 120.265 155.125 1.00 47.37  ?  219 VAL A CA  1 
ATOM   1483  C  C   . VAL A 1 230 ? 152.077 120.450 156.481 1.00 47.37  ?  219 VAL A C   1 
ATOM   1484  O  O   . VAL A 1 230 ? 152.609 120.043 157.522 1.00 47.37  ?  219 VAL A O   1 
ATOM   1485  C  CB  . VAL A 1 230 ? 153.514 121.529 154.687 1.00 47.37  ?  219 VAL A CB  1 
ATOM   1486  C  CG1 . VAL A 1 230 ? 154.510 121.941 155.742 1.00 47.37  ?  219 VAL A CG1 1 
ATOM   1487  C  CG2 . VAL A 1 230 ? 154.217 121.282 153.380 1.00 47.37  ?  219 VAL A CG2 1 
ATOM   1488  N  N   . HIS A 1 231 ? 150.890 121.056 156.485 1.00 48.51  ?  220 HIS A N   1 
ATOM   1489  C  CA  . HIS A 1 231 ? 150.111 121.187 157.714 1.00 48.51  ?  220 HIS A CA  1 
ATOM   1490  C  C   . HIS A 1 231 ? 149.805 119.829 158.330 1.00 48.51  ?  220 HIS A C   1 
ATOM   1491  O  O   . HIS A 1 231 ? 149.928 119.644 159.543 1.00 48.51  ?  220 HIS A O   1 
ATOM   1492  C  CB  . HIS A 1 231 ? 148.808 121.927 157.428 1.00 48.51  ?  220 HIS A CB  1 
ATOM   1493  C  CG  . HIS A 1 231 ? 148.909 123.410 157.548 1.00 48.51  ?  220 HIS A CG  1 
ATOM   1494  N  ND1 . HIS A 1 231 ? 148.743 124.071 158.742 1.00 48.51  ?  220 HIS A ND1 1 
ATOM   1495  C  CD2 . HIS A 1 231 ? 149.141 124.363 156.619 1.00 48.51  ?  220 HIS A CD2 1 
ATOM   1496  C  CE1 . HIS A 1 231 ? 148.878 125.368 158.545 1.00 48.51  ?  220 HIS A CE1 1 
ATOM   1497  N  NE2 . HIS A 1 231 ? 149.120 125.572 157.266 1.00 48.51  ?  220 HIS A NE2 1 
ATOM   1498  N  N   . VAL A 1 232 ? 149.374 118.873 157.509 1.00 49.23  ?  221 VAL A N   1 
ATOM   1499  C  CA  . VAL A 1 232 ? 149.036 117.546 158.011 1.00 49.23  ?  221 VAL A CA  1 
ATOM   1500  C  C   . VAL A 1 232 ? 150.273 116.851 158.560 1.00 49.23  ?  221 VAL A C   1 
ATOM   1501  O  O   . VAL A 1 232 ? 150.225 116.207 159.615 1.00 49.23  ?  221 VAL A O   1 
ATOM   1502  C  CB  . VAL A 1 232 ? 148.365 116.712 156.904 1.00 49.23  ?  221 VAL A CB  1 
ATOM   1503  C  CG1 . VAL A 1 232 ? 148.294 115.259 157.302 1.00 49.23  ?  221 VAL A CG1 1 
ATOM   1504  C  CG2 . VAL A 1 232 ? 146.984 117.237 156.604 1.00 49.23  ?  221 VAL A CG2 1 
ATOM   1505  N  N   . LEU A 1 233 ? 151.393 116.959 157.848 1.00 51.12  ?  222 LEU A N   1 
ATOM   1506  C  CA  . LEU A 1 233 ? 152.646 116.396 158.330 1.00 51.12  ?  222 LEU A CA  1 
ATOM   1507  C  C   . LEU A 1 233 ? 152.985 116.927 159.713 1.00 51.12  ?  222 LEU A C   1 
ATOM   1508  O  O   . LEU A 1 233 ? 153.332 116.162 160.615 1.00 51.12  ?  222 LEU A O   1 
ATOM   1509  C  CB  . LEU A 1 233 ? 153.765 116.716 157.344 1.00 51.12  ?  222 LEU A CB  1 
ATOM   1510  C  CG  . LEU A 1 233 ? 154.998 115.821 157.279 1.00 51.12  ?  222 LEU A CG  1 
ATOM   1511  C  CD1 . LEU A 1 233 ? 155.748 116.117 156.012 1.00 51.12  ?  222 LEU A CD1 1 
ATOM   1512  C  CD2 . LEU A 1 233 ? 155.896 116.031 158.468 1.00 51.12  ?  222 LEU A CD2 1 
ATOM   1513  N  N   . VAL A 1 234 ? 152.903 118.244 159.895 1.00 51.70  ?  223 VAL A N   1 
ATOM   1514  C  CA  . VAL A 1 234 ? 153.228 118.810 161.197 1.00 51.70  ?  223 VAL A CA  1 
ATOM   1515  C  C   . VAL A 1 234 ? 152.213 118.372 162.242 1.00 51.70  ?  223 VAL A C   1 
ATOM   1516  O  O   . VAL A 1 234 ? 152.561 118.169 163.408 1.00 51.70  ?  223 VAL A O   1 
ATOM   1517  C  CB  . VAL A 1 234 ? 153.332 120.340 161.095 1.00 51.70  ?  223 VAL A CB  1 
ATOM   1518  C  CG1 . VAL A 1 234 ? 153.396 120.967 162.464 1.00 51.70  ?  223 VAL A CG1 1 
ATOM   1519  C  CG2 . VAL A 1 234 ? 154.553 120.719 160.298 1.00 51.70  ?  223 VAL A CG2 1 
ATOM   1520  N  N   . SER A 1 235 ? 150.958 118.187 161.848 1.00 52.94  ?  224 SER A N   1 
ATOM   1521  C  CA  . SER A 1 235 ? 149.928 117.750 162.778 1.00 52.94  ?  224 SER A CA  1 
ATOM   1522  C  C   . SER A 1 235 ? 150.131 116.332 163.278 1.00 52.94  ?  224 SER A C   1 
ATOM   1523  O  O   . SER A 1 235 ? 149.648 116.004 164.361 1.00 52.94  ?  224 SER A O   1 
ATOM   1524  C  CB  . SER A 1 235 ? 148.560 117.850 162.122 1.00 52.94  ?  224 SER A CB  1 
ATOM   1525  O  OG  . SER A 1 235 ? 148.128 119.188 162.094 1.00 52.94  ?  224 SER A OG  1 
ATOM   1526  N  N   . GLN A 1 236 ? 150.807 115.485 162.517 1.00 54.12  ?  225 GLN A N   1 
ATOM   1527  C  CA  . GLN A 1 236 ? 151.021 114.112 162.949 1.00 54.12  ?  225 GLN A CA  1 
ATOM   1528  C  C   . GLN A 1 236 ? 152.197 113.948 163.896 1.00 54.12  ?  225 GLN A C   1 
ATOM   1529  O  O   . GLN A 1 236 ? 152.367 112.862 164.456 1.00 54.12  ?  225 GLN A O   1 
ATOM   1530  C  CB  . GLN A 1 236 ? 151.229 113.198 161.743 1.00 54.12  ?  225 GLN A CB  1 
ATOM   1531  C  CG  . GLN A 1 236 ? 150.156 113.298 160.694 1.00 54.12  ?  225 GLN A CG  1 
ATOM   1532  C  CD  . GLN A 1 236 ? 148.842 112.725 161.140 1.00 54.12  ?  225 GLN A CD  1 
ATOM   1533  O  OE1 . GLN A 1 236 ? 148.703 112.244 162.257 1.00 54.12  ?  225 GLN A OE1 1 
ATOM   1534  N  NE2 . GLN A 1 236 ? 147.862 112.772 160.262 1.00 54.12  ?  225 GLN A NE2 1 
ATOM   1535  N  N   . LEU A 1 237 ? 153.001 114.988 164.095 1.00 54.94  ?  226 LEU A N   1 
ATOM   1536  C  CA  . LEU A 1 237 ? 154.227 114.842 164.868 1.00 54.94  ?  226 LEU A CA  1 
ATOM   1537  C  C   . LEU A 1 237 ? 153.950 114.599 166.341 1.00 54.94  ?  226 LEU A C   1 
ATOM   1538  O  O   . LEU A 1 237 ? 154.710 113.886 166.997 1.00 54.94  ?  226 LEU A O   1 
ATOM   1539  C  CB  . LEU A 1 237 ? 155.102 116.076 164.694 1.00 54.94  ?  226 LEU A CB  1 
ATOM   1540  C  CG  . LEU A 1 237 ? 155.643 116.297 163.289 1.00 54.94  ?  226 LEU A CG  1 
ATOM   1541  C  CD1 . LEU A 1 237 ? 156.583 117.472 163.281 1.00 54.94  ?  226 LEU A CD1 1 
ATOM   1542  C  CD2 . LEU A 1 237 ? 156.328 115.047 162.778 1.00 54.94  ?  226 LEU A CD2 1 
ATOM   1543  N  N   . LYS A 1 238 ? 152.879 115.175 166.881 1.00 55.56  ?  227 LYS A N   1 
ATOM   1544  C  CA  . LYS A 1 238 ? 152.551 114.939 168.278 1.00 55.56  ?  227 LYS A CA  1 
ATOM   1545  C  C   . LYS A 1 238 ? 152.139 113.502 168.542 1.00 55.56  ?  227 LYS A C   1 
ATOM   1546  O  O   . LYS A 1 238 ? 152.166 113.074 169.696 1.00 55.56  ?  227 LYS A O   1 
ATOM   1547  C  CB  . LYS A 1 238 ? 151.441 115.882 168.730 1.00 55.56  ?  227 LYS A CB  1 
ATOM   1548  C  CG  . LYS A 1 238 ? 150.157 115.710 167.976 1.00 55.56  ?  227 LYS A CG  1 
ATOM   1549  C  CD  . LYS A 1 238 ? 149.168 116.793 168.308 1.00 55.56  ?  227 LYS A CD  1 
ATOM   1550  C  CE  . LYS A 1 238 ? 148.604 116.598 169.689 1.00 55.56  ?  227 LYS A CE  1 
ATOM   1551  N  NZ  . LYS A 1 238 ? 147.596 117.638 170.018 1.00 55.56  1  227 LYS A NZ  1 
ATOM   1552  N  N   . PHE A 1 239 ? 151.753 112.752 167.515 1.00 54.29  ?  228 PHE A N   1 
ATOM   1553  C  CA  . PHE A 1 239 ? 151.431 111.341 167.680 1.00 54.29  ?  228 PHE A CA  1 
ATOM   1554  C  C   . PHE A 1 239 ? 152.596 110.435 167.333 1.00 54.29  ?  228 PHE A C   1 
ATOM   1555  O  O   . PHE A 1 239 ? 152.739 109.372 167.937 1.00 54.29  ?  228 PHE A O   1 
ATOM   1556  C  CB  . PHE A 1 239 ? 150.225 110.967 166.821 1.00 54.29  ?  228 PHE A CB  1 
ATOM   1557  C  CG  . PHE A 1 239 ? 149.022 111.796 167.094 1.00 54.29  ?  228 PHE A CG  1 
ATOM   1558  C  CD1 . PHE A 1 239 ? 148.314 111.638 168.263 1.00 54.29  ?  228 PHE A CD1 1 
ATOM   1559  C  CD2 . PHE A 1 239 ? 148.607 112.749 166.192 1.00 54.29  ?  228 PHE A CD2 1 
ATOM   1560  C  CE1 . PHE A 1 239 ? 147.215 112.406 168.520 1.00 54.29  ?  228 PHE A CE1 1 
ATOM   1561  C  CE2 . PHE A 1 239 ? 147.511 113.517 166.446 1.00 54.29  ?  228 PHE A CE2 1 
ATOM   1562  C  CZ  . PHE A 1 239 ? 146.814 113.346 167.612 1.00 54.29  ?  228 PHE A CZ  1 
ATOM   1563  N  N   . ILE A 1 240 ? 153.430 110.832 166.374 1.00 57.04  ?  229 ILE A N   1 
ATOM   1564  C  CA  . ILE A 1 240 ? 154.639 110.069 166.092 1.00 57.04  ?  229 ILE A CA  1 
ATOM   1565  C  C   . ILE A 1 240 ? 155.556 110.052 167.306 1.00 57.04  ?  229 ILE A C   1 
ATOM   1566  O  O   . ILE A 1 240 ? 156.136 109.017 167.642 1.00 57.04  ?  229 ILE A O   1 
ATOM   1567  C  CB  . ILE A 1 240 ? 155.355 110.646 164.859 1.00 57.04  ?  229 ILE A CB  1 
ATOM   1568  C  CG1 . ILE A 1 240 ? 154.445 110.590 163.640 1.00 57.04  ?  229 ILE A CG1 1 
ATOM   1569  C  CG2 . ILE A 1 240 ? 156.630 109.899 164.587 1.00 57.04  ?  229 ILE A CG2 1 
ATOM   1570  C  CD1 . ILE A 1 240 ? 153.863 109.254 163.397 1.00 57.04  ?  229 ILE A CD1 1 
ATOM   1571  N  N   . PHE A 1 241 ? 155.703 111.192 167.981 1.00 59.20  ?  230 PHE A N   1 
ATOM   1572  C  CA  . PHE A 1 241 ? 156.548 111.307 169.157 1.00 59.20  ?  230 PHE A CA  1 
ATOM   1573  C  C   . PHE A 1 241 ? 155.797 111.115 170.464 1.00 59.20  ?  230 PHE A C   1 
ATOM   1574  O  O   . PHE A 1 241 ? 156.437 110.931 171.500 1.00 59.20  ?  230 PHE A O   1 
ATOM   1575  C  CB  . PHE A 1 241 ? 157.233 112.679 169.187 1.00 59.20  ?  230 PHE A CB  1 
ATOM   1576  C  CG  . PHE A 1 241 ? 158.015 112.997 167.952 1.00 59.20  ?  230 PHE A CG  1 
ATOM   1577  C  CD1 . PHE A 1 241 ? 158.903 112.087 167.427 1.00 59.20  ?  230 PHE A CD1 1 
ATOM   1578  C  CD2 . PHE A 1 241 ? 157.866 114.211 167.320 1.00 59.20  ?  230 PHE A CD2 1 
ATOM   1579  C  CE1 . PHE A 1 241 ? 159.614 112.379 166.299 1.00 59.20  ?  230 PHE A CE1 1 
ATOM   1580  C  CE2 . PHE A 1 241 ? 158.579 114.503 166.191 1.00 59.20  ?  230 PHE A CE2 1 
ATOM   1581  C  CZ  . PHE A 1 241 ? 159.451 113.587 165.682 1.00 59.20  ?  230 PHE A CZ  1 
ATOM   1582  N  N   . GLN A 1 242 ? 154.467 111.153 170.435 1.00 59.71  ?  231 GLN A N   1 
ATOM   1583  C  CA  . GLN A 1 242 ? 153.627 111.108 171.629 1.00 59.71  ?  231 GLN A CA  1 
ATOM   1584  C  C   . GLN A 1 242 ? 153.923 112.266 172.573 1.00 59.71  ?  231 GLN A C   1 
ATOM   1585  O  O   . GLN A 1 242 ? 154.270 112.071 173.737 1.00 59.71  ?  231 GLN A O   1 
ATOM   1586  C  CB  . GLN A 1 242 ? 153.747 109.773 172.358 1.00 59.71  ?  231 GLN A CB  1 
ATOM   1587  C  CG  . GLN A 1 242 ? 152.522 109.443 173.162 1.00 59.71  ?  231 GLN A CG  1 
ATOM   1588  C  CD  . GLN A 1 242 ? 152.821 108.563 174.335 1.00 59.71  ?  231 GLN A CD  1 
ATOM   1589  O  OE1 . GLN A 1 242 ? 153.584 107.613 174.229 1.00 59.71  ?  231 GLN A OE1 1 
ATOM   1590  N  NE2 . GLN A 1 242 ? 152.226 108.877 175.472 1.00 59.71  ?  231 GLN A NE2 1 
ATOM   1591  N  N   . LEU A 1 243 ? 153.772 113.480 172.069 1.00 59.74  ?  232 LEU A N   1 
ATOM   1592  C  CA  . LEU A 1 243 ? 153.977 114.685 172.849 1.00 59.74  ?  232 LEU A CA  1 
ATOM   1593  C  C   . LEU A 1 243 ? 152.652 115.400 173.057 1.00 59.74  ?  232 LEU A C   1 
ATOM   1594  O  O   . LEU A 1 243 ? 151.717 115.255 172.272 1.00 59.74  ?  232 LEU A O   1 
ATOM   1595  C  CB  . LEU A 1 243 ? 154.968 115.614 172.151 1.00 59.74  ?  232 LEU A CB  1 
ATOM   1596  C  CG  . LEU A 1 243 ? 156.367 115.047 171.934 1.00 59.74  ?  232 LEU A CG  1 
ATOM   1597  C  CD1 . LEU A 1 243 ? 157.155 115.954 171.038 1.00 59.74  ?  232 LEU A CD1 1 
ATOM   1598  C  CD2 . LEU A 1 243 ? 157.076 114.861 173.252 1.00 59.74  ?  232 LEU A CD2 1 
ATOM   1599  N  N   . THR A 1 244 ? 152.579 116.176 174.131 1.00 61.55  ?  233 THR A N   1 
ATOM   1600  C  CA  . THR A 1 244 ? 151.395 116.965 174.438 1.00 61.55  ?  233 THR A CA  1 
ATOM   1601  C  C   . THR A 1 244 ? 151.588 118.363 173.870 1.00 61.55  ?  233 THR A C   1 
ATOM   1602  O  O   . THR A 1 244 ? 152.527 119.067 174.247 1.00 61.55  ?  233 THR A O   1 
ATOM   1603  C  CB  . THR A 1 244 ? 151.148 117.021 175.941 1.00 61.55  ?  233 THR A CB  1 
ATOM   1604  O  OG1 . THR A 1 244 ? 151.188 115.697 176.476 1.00 61.55  ?  233 THR A OG1 1 
ATOM   1605  C  CG2 . THR A 1 244 ? 149.793 117.632 176.227 1.00 61.55  ?  233 THR A CG2 1 
ATOM   1606  N  N   . VAL A 1 245 ? 150.704 118.760 172.968 1.00 58.66  ?  234 VAL A N   1 
ATOM   1607  C  CA  . VAL A 1 245 ? 150.826 120.016 172.237 1.00 58.66  ?  234 VAL A CA  1 
ATOM   1608  C  C   . VAL A 1 245 ? 149.575 120.843 172.503 1.00 58.66  ?  234 VAL A C   1 
ATOM   1609  O  O   . VAL A 1 245 ? 148.468 120.297 172.474 1.00 58.66  ?  234 VAL A O   1 
ATOM   1610  C  CB  . VAL A 1 245 ? 151.026 119.766 170.733 1.00 58.66  ?  234 VAL A CB  1 
ATOM   1611  C  CG1 . VAL A 1 245 ? 150.869 121.040 169.941 1.00 58.66  ?  234 VAL A CG1 1 
ATOM   1612  C  CG2 . VAL A 1 245 ? 152.386 119.161 170.489 1.00 58.66  ?  234 VAL A CG2 1 
ATOM   1613  N  N   . PRO A 1 246 ? 149.701 122.132 172.794 1.00 59.23  ?  235 PRO A N   1 
ATOM   1614  C  CA  . PRO A 1 246 ? 148.515 122.959 173.029 1.00 59.23  ?  235 PRO A CA  1 
ATOM   1615  C  C   . PRO A 1 246 ? 147.660 123.092 171.780 1.00 59.23  ?  235 PRO A C   1 
ATOM   1616  O  O   . PRO A 1 246 ? 148.065 122.760 170.667 1.00 59.23  ?  235 PRO A O   1 
ATOM   1617  C  CB  . PRO A 1 246 ? 149.099 124.311 173.443 1.00 59.23  ?  235 PRO A CB  1 
ATOM   1618  C  CG  . PRO A 1 246 ? 150.455 124.008 173.910 1.00 59.23  ?  235 PRO A CG  1 
ATOM   1619  C  CD  . PRO A 1 246 ? 150.940 122.857 173.105 1.00 59.23  ?  235 PRO A CD  1 
ATOM   1620  N  N   . SER A 1 247 ? 146.448 123.601 171.987 1.00 58.96  ?  236 SER A N   1 
ATOM   1621  C  CA  . SER A 1 247 ? 145.482 123.781 170.906 1.00 58.96  ?  236 SER A CA  1 
ATOM   1622  C  C   . SER A 1 247 ? 145.696 125.153 170.278 1.00 58.96  ?  236 SER A C   1 
ATOM   1623  O  O   . SER A 1 247 ? 144.939 126.100 170.492 1.00 58.96  ?  236 SER A O   1 
ATOM   1624  C  CB  . SER A 1 247 ? 144.065 123.618 171.431 1.00 58.96  ?  236 SER A CB  1 
ATOM   1625  O  OG  . SER A 1 247 ? 143.684 122.256 171.434 1.00 58.96  ?  236 SER A OG  1 
ATOM   1626  N  N   . HIS A 1 248 ? 146.724 125.220 169.442 1.00 58.53  ?  237 HIS A N   1 
ATOM   1627  C  CA  . HIS A 1 248 ? 147.105 126.435 168.741 1.00 58.53  ?  237 HIS A CA  1 
ATOM   1628  C  C   . HIS A 1 248 ? 146.104 126.785 167.667 1.00 58.53  ?  237 HIS A C   1 
ATOM   1629  O  O   . HIS A 1 248 ? 145.427 125.924 167.126 1.00 58.53  ?  237 HIS A O   1 
ATOM   1630  C  CB  . HIS A 1 248 ? 148.477 126.272 168.096 1.00 58.53  ?  237 HIS A CB  1 
ATOM   1631  C  CG  . HIS A 1 248 ? 149.586 126.053 169.075 1.00 58.53  ?  237 HIS A CG  1 
ATOM   1632  N  ND1 . HIS A 1 248 ? 149.919 126.978 170.037 1.00 58.53  ?  237 HIS A ND1 1 
ATOM   1633  C  CD2 . HIS A 1 248 ? 150.448 125.025 169.228 1.00 58.53  ?  237 HIS A CD2 1 
ATOM   1634  C  CE1 . HIS A 1 248 ? 150.935 126.527 170.743 1.00 58.53  ?  237 HIS A CE1 1 
ATOM   1635  N  NE2 . HIS A 1 248 ? 151.275 125.345 170.272 1.00 58.53  ?  237 HIS A NE2 1 
ATOM   1636  N  N   . THR A 1 249 ? 146.024 128.066 167.352 1.00 60.02  ?  238 THR A N   1 
ATOM   1637  C  CA  . THR A 1 249 ? 145.129 128.546 166.320 1.00 60.02  ?  238 THR A CA  1 
ATOM   1638  C  C   . THR A 1 249 ? 145.915 129.392 165.335 1.00 60.02  ?  238 THR A C   1 
ATOM   1639  O  O   . THR A 1 249 ? 147.073 129.688 165.555 1.00 60.02  ?  238 THR A O   1 
ATOM   1640  C  CB  . THR A 1 249 ? 143.975 129.376 166.899 1.00 60.02  ?  238 THR A CB  1 
ATOM   1641  O  OG1 . THR A 1 249 ? 144.500 130.369 167.783 1.00 60.02  ?  238 THR A OG1 1 
ATOM   1642  C  CG2 . THR A 1 249 ? 143.016 128.496 167.662 1.00 60.02  ?  238 THR A CG2 1 
ATOM   1643  N  N   . ASP A 1 250 ? 145.271 129.785 164.251 1.00 59.88  ?  239 ASP A N   1 
ATOM   1644  C  CA  . ASP A 1 250 ? 145.916 130.584 163.227 1.00 59.88  ?  239 ASP A CA  1 
ATOM   1645  C  C   . ASP A 1 250 ? 145.785 132.060 163.525 1.00 59.88  ?  239 ASP A C   1 
ATOM   1646  O  O   . ASP A 1 250 ? 144.827 132.472 164.159 1.00 59.88  ?  239 ASP A O   1 
ATOM   1647  C  CB  . ASP A 1 250 ? 145.325 130.242 161.865 1.00 59.88  ?  239 ASP A CB  1 
ATOM   1648  C  CG  . ASP A 1 250 ? 146.000 129.052 161.229 1.00 59.88  ?  239 ASP A CG  1 
ATOM   1649  O  OD1 . ASP A 1 250 ? 147.238 129.044 161.161 1.00 59.88  ?  239 ASP A OD1 1 
ATOM   1650  O  OD2 . ASP A 1 250 ? 145.297 128.127 160.791 1.00 59.88  -1 239 ASP A OD2 1 
ATOM   1651  N  N   . PRO A 1 251 ? 146.761 132.869 163.089 1.00 59.12  ?  240 PRO A N   1 
ATOM   1652  C  CA  . PRO A 1 251 ? 147.730 132.631 162.023 1.00 59.12  ?  240 PRO A CA  1 
ATOM   1653  C  C   . PRO A 1 251 ? 148.977 131.975 162.549 1.00 59.12  ?  240 PRO A C   1 
ATOM   1654  O  O   . PRO A 1 251 ? 149.138 131.885 163.746 1.00 59.12  ?  240 PRO A O   1 
ATOM   1655  C  CB  . PRO A 1 251 ? 148.049 134.039 161.537 1.00 59.12  ?  240 PRO A CB  1 
ATOM   1656  C  CG  . PRO A 1 251 ? 147.886 134.891 162.741 1.00 59.12  ?  240 PRO A CG  1 
ATOM   1657  C  CD  . PRO A 1 251 ? 146.916 134.214 163.666 1.00 59.12  ?  240 PRO A CD  1 
ATOM   1658  N  N   . VAL A 1 252 ? 149.776 131.425 161.647 1.00 55.12  ?  241 VAL A N   1 
ATOM   1659  C  CA  . VAL A 1 252 ? 151.057 130.767 161.926 1.00 55.12  ?  241 VAL A CA  1 
ATOM   1660  C  C   . VAL A 1 252 ? 151.008 129.646 162.950 1.00 55.12  ?  241 VAL A C   1 
ATOM   1661  O  O   . VAL A 1 252 ? 151.963 129.421 163.664 1.00 55.12  ?  241 VAL A O   1 
ATOM   1662  C  CB  . VAL A 1 252 ? 152.241 131.749 162.166 1.00 55.12  ?  241 VAL A CB  1 
ATOM   1663  C  CG1 . VAL A 1 252 ? 152.181 132.911 161.199 1.00 55.12  ?  241 VAL A CG1 1 
ATOM   1664  C  CG2 . VAL A 1 252 ? 152.324 132.238 163.601 1.00 55.12  ?  241 VAL A CG2 1 
ATOM   1665  N  N   . SER A 1 253 ? 149.909 128.904 162.958 1.00 55.48  ?  242 SER A N   1 
ATOM   1666  C  CA  . SER A 1 253 ? 149.705 127.777 163.846 1.00 55.48  ?  242 SER A CA  1 
ATOM   1667  C  C   . SER A 1 253 ? 150.671 126.650 163.540 1.00 55.48  ?  242 SER A C   1 
ATOM   1668  O  O   . SER A 1 253 ? 151.048 125.911 164.426 1.00 55.48  ?  242 SER A O   1 
ATOM   1669  C  CB  . SER A 1 253 ? 148.255 127.309 163.848 1.00 55.48  ?  242 SER A CB  1 
ATOM   1670  O  OG  . SER A 1 253 ? 147.941 126.618 162.671 1.00 55.48  ?  242 SER A OG  1 
ATOM   1671  N  N   . ILE A 1 254 ? 151.032 126.483 162.275 1.00 52.48  ?  243 ILE A N   1 
ATOM   1672  C  CA  . ILE A 1 254 ? 151.968 125.443 161.896 1.00 52.48  ?  243 ILE A CA  1 
ATOM   1673  C  C   . ILE A 1 254 ? 153.320 125.666 162.583 1.00 52.48  ?  243 ILE A C   1 
ATOM   1674  O  O   . ILE A 1 254 ? 153.938 124.721 163.029 1.00 52.48  ?  243 ILE A O   1 
ATOM   1675  C  CB  . ILE A 1 254 ? 152.059 125.285 160.350 1.00 52.48  ?  243 ILE A CB  1 
ATOM   1676  C  CG1 . ILE A 1 254 ? 152.870 124.054 159.959 1.00 52.48  ?  243 ILE A CG1 1 
ATOM   1677  C  CG2 . ILE A 1 254 ? 152.598 126.529 159.655 1.00 52.48  ?  243 ILE A CG2 1 
ATOM   1678  C  CD1 . ILE A 1 254 ? 152.841 123.779 158.478 1.00 52.48  ?  243 ILE A CD1 1 
ATOM   1679  N  N   . PHE A 1 255 ? 153.779 126.910 162.644 1.00 53.27  ?  244 PHE A N   1 
ATOM   1680  C  CA  . PHE A 1 255 ? 155.015 127.272 163.325 1.00 53.27  ?  244 PHE A CA  1 
ATOM   1681  C  C   . PHE A 1 255 ? 154.901 127.114 164.824 1.00 53.27  ?  244 PHE A C   1 
ATOM   1682  O  O   . PHE A 1 255 ? 155.839 126.714 165.477 1.00 53.27  ?  244 PHE A O   1 
ATOM   1683  C  CB  . PHE A 1 255 ? 155.464 128.673 162.942 1.00 53.27  ?  244 PHE A CB  1 
ATOM   1684  C  CG  . PHE A 1 255 ? 155.804 128.803 161.499 1.00 53.27  ?  244 PHE A CG  1 
ATOM   1685  C  CD1 . PHE A 1 255 ? 156.875 128.121 160.977 1.00 53.27  ?  244 PHE A CD1 1 
ATOM   1686  C  CD2 . PHE A 1 255 ? 155.041 129.578 160.661 1.00 53.27  ?  244 PHE A CD2 1 
ATOM   1687  C  CE1 . PHE A 1 255 ? 157.194 128.223 159.644 1.00 53.27  ?  244 PHE A CE1 1 
ATOM   1688  C  CE2 . PHE A 1 255 ? 155.354 129.681 159.326 1.00 53.27  ?  244 PHE A CE2 1 
ATOM   1689  C  CZ  . PHE A 1 255 ? 156.433 129.005 158.817 1.00 53.27  ?  244 PHE A CZ  1 
ATOM   1690  N  N   . LYS A 1 256 ? 153.742 127.474 165.357 1.00 54.34  ?  245 LYS A N   1 
ATOM   1691  C  CA  . LYS A 1 256 ? 153.465 127.352 166.772 1.00 54.34  ?  245 LYS A CA  1 
ATOM   1692  C  C   . LYS A 1 256 ? 153.507 125.903 167.197 1.00 54.34  ?  245 LYS A C   1 
ATOM   1693  O  O   . LYS A 1 256 ? 154.006 125.594 168.259 1.00 54.34  ?  245 LYS A O   1 
ATOM   1694  C  CB  . LYS A 1 256 ? 152.094 127.907 167.094 1.00 54.34  ?  245 LYS A CB  1 
ATOM   1695  C  CG  . LYS A 1 256 ? 151.934 129.395 166.917 1.00 54.34  ?  245 LYS A CG  1 
ATOM   1696  C  CD  . LYS A 1 256 ? 150.503 129.760 167.229 1.00 54.34  ?  245 LYS A CD  1 
ATOM   1697  C  CE  . LYS A 1 256 ? 150.185 131.176 166.827 1.00 54.34  ?  245 LYS A CE  1 
ATOM   1698  N  NZ  . LYS A 1 256 ? 148.741 131.452 167.012 1.00 54.34  1  245 LYS A NZ  1 
ATOM   1699  N  N   . VAL A 1 257 ? 152.964 125.018 166.373 1.00 54.72  ?  246 VAL A N   1 
ATOM   1700  C  CA  . VAL A 1 257 ? 152.953 123.594 166.664 1.00 54.72  ?  246 VAL A CA  1 
ATOM   1701  C  C   . VAL A 1 257 ? 154.341 123.009 166.538 1.00 54.72  ?  246 VAL A C   1 
ATOM   1702  O  O   . VAL A 1 257 ? 154.724 122.153 167.309 1.00 54.72  ?  246 VAL A O   1 
ATOM   1703  C  CB  . VAL A 1 257 ? 152.024 122.812 165.718 1.00 54.72  ?  246 VAL A CB  1 
ATOM   1704  C  CG1 . VAL A 1 257 ? 152.269 121.325 165.850 1.00 54.72  ?  246 VAL A CG1 1 
ATOM   1705  C  CG2 . VAL A 1 257 ? 150.574 123.139 165.988 1.00 54.72  ?  246 VAL A CG2 1 
ATOM   1706  N  N   . LEU A 1 258 ? 155.082 123.449 165.535 1.00 54.69  ?  247 LEU A N   1 
ATOM   1707  C  CA  . LEU A 1 258 ? 156.438 122.968 165.334 1.00 54.69  ?  247 LEU A CA  1 
ATOM   1708  C  C   . LEU A 1 258 ? 157.308 123.330 166.512 1.00 54.69  ?  247 LEU A C   1 
ATOM   1709  O  O   . LEU A 1 258 ? 158.161 122.564 166.916 1.00 54.69  ?  247 LEU A O   1 
ATOM   1710  C  CB  . LEU A 1 258 ? 157.040 123.565 164.072 1.00 54.69  ?  247 LEU A CB  1 
ATOM   1711  C  CG  . LEU A 1 258 ? 156.894 122.829 162.752 1.00 54.69  ?  247 LEU A CG  1 
ATOM   1712  C  CD1 . LEU A 1 258 ? 157.474 123.685 161.645 1.00 54.69  ?  247 LEU A CD1 1 
ATOM   1713  C  CD2 . LEU A 1 258 ? 157.599 121.490 162.819 1.00 54.69  ?  247 LEU A CD2 1 
ATOM   1714  N  N   . TYR A 1 259 ? 157.134 124.540 167.022 1.00 58.53  ?  248 TYR A N   1 
ATOM   1715  C  CA  . TYR A 1 259 ? 157.882 124.950 168.174 1.00 58.53  ?  248 TYR A CA  1 
ATOM   1716  C  C   . TYR A 1 259 ? 157.516 124.092 169.368 1.00 58.53  ?  248 TYR A C   1 
ATOM   1717  O  O   . TYR A 1 259 ? 158.383 123.654 170.090 1.00 58.53  ?  248 TYR A O   1 
ATOM   1718  C  CB  . TYR A 1 259 ? 157.642 126.411 168.521 1.00 58.53  ?  248 TYR A CB  1 
ATOM   1719  C  CG  . TYR A 1 259 ? 158.307 126.747 169.823 1.00 58.53  ?  248 TYR A CG  1 
ATOM   1720  C  CD1 . TYR A 1 259 ? 157.573 126.880 170.982 1.00 58.53  ?  248 TYR A CD1 1 
ATOM   1721  C  CD2 . TYR A 1 259 ? 159.680 126.858 169.903 1.00 58.53  ?  248 TYR A CD2 1 
ATOM   1722  C  CE1 . TYR A 1 259 ? 158.186 127.156 172.178 1.00 58.53  ?  248 TYR A CE1 1 
ATOM   1723  C  CE2 . TYR A 1 259 ? 160.302 127.130 171.096 1.00 58.53  ?  248 TYR A CE2 1 
ATOM   1724  C  CZ  . TYR A 1 259 ? 159.547 127.281 172.227 1.00 58.53  ?  248 TYR A CZ  1 
ATOM   1725  O  OH  . TYR A 1 259 ? 160.163 127.555 173.420 1.00 58.53  ?  248 TYR A OH  1 
ATOM   1726  N  N   . SER A 1 260 ? 156.229 123.833 169.555 1.00 57.79  ?  249 SER A N   1 
ATOM   1727  C  CA  . SER A 1 260 ? 155.786 123.024 170.672 1.00 57.79  ?  249 SER A CA  1 
ATOM   1728  C  C   . SER A 1 260 ? 156.340 121.629 170.574 1.00 57.79  ?  249 SER A C   1 
ATOM   1729  O  O   . SER A 1 260 ? 156.775 121.076 171.555 1.00 57.79  ?  249 SER A O   1 
ATOM   1730  C  CB  . SER A 1 260 ? 154.272 122.934 170.704 1.00 57.79  ?  249 SER A CB  1 
ATOM   1731  O  OG  . SER A 1 260 ? 153.692 124.207 170.767 1.00 57.79  ?  249 SER A OG  1 
ATOM   1732  N  N   . VAL A 1 261 ? 156.302 121.047 169.389 1.00 57.48  ?  250 VAL A N   1 
ATOM   1733  C  CA  . VAL A 1 261 ? 156.836 119.713 169.205 1.00 57.48  ?  250 VAL A CA  1 
ATOM   1734  C  C   . VAL A 1 261 ? 158.344 119.616 169.412 1.00 57.48  ?  250 VAL A C   1 
ATOM   1735  O  O   . VAL A 1 261 ? 158.814 118.716 170.067 1.00 57.48  ?  250 VAL A O   1 
ATOM   1736  C  CB  . VAL A 1 261 ? 156.498 119.171 167.801 1.00 57.48  ?  250 VAL A CB  1 
ATOM   1737  C  CG1 . VAL A 1 261 ? 157.483 118.097 167.386 1.00 57.48  ?  250 VAL A CG1 1 
ATOM   1738  C  CG2 . VAL A 1 261 ? 155.077 118.647 167.756 1.00 57.48  ?  250 VAL A CG2 1 
ATOM   1739  N  N   . PHE A 1 262 ? 159.101 120.545 168.846 1.00 59.34  ?  251 PHE A N   1 
ATOM   1740  C  CA  . PHE A 1 262 ? 160.562 120.517 168.975 1.00 59.34  ?  251 PHE A CA  1 
ATOM   1741  C  C   . PHE A 1 262 ? 161.197 121.013 170.262 1.00 59.34  ?  251 PHE A C   1 
ATOM   1742  O  O   . PHE A 1 262 ? 162.296 120.615 170.598 1.00 59.34  ?  251 PHE A O   1 
ATOM   1743  C  CB  . PHE A 1 262 ? 161.251 121.006 167.709 1.00 59.34  ?  251 PHE A CB  1 
ATOM   1744  C  CG  . PHE A 1 262 ? 161.009 120.105 166.549 1.00 59.34  ?  251 PHE A CG  1 
ATOM   1745  C  CD1 . PHE A 1 262 ? 161.535 118.837 166.537 1.00 59.34  ?  251 PHE A CD1 1 
ATOM   1746  C  CD2 . PHE A 1 262 ? 160.189 120.491 165.520 1.00 59.34  ?  251 PHE A CD2 1 
ATOM   1747  C  CE1 . PHE A 1 262 ? 161.284 117.980 165.491 1.00 59.34  ?  251 PHE A CE1 1 
ATOM   1748  C  CE2 . PHE A 1 262 ? 159.931 119.645 164.470 1.00 59.34  ?  251 PHE A CE2 1 
ATOM   1749  C  CZ  . PHE A 1 262 ? 160.480 118.384 164.454 1.00 59.34  ?  251 PHE A CZ  1 
ATOM   1750  N  N   . SER A 1 263 ? 160.510 121.896 170.973 1.00 60.76  ?  252 SER A N   1 
ATOM   1751  C  CA  . SER A 1 263 ? 161.004 122.377 172.248 1.00 60.76  ?  252 SER A CA  1 
ATOM   1752  C  C   . SER A 1 263 ? 161.065 121.243 173.267 1.00 60.76  ?  252 SER A C   1 
ATOM   1753  O  O   . SER A 1 263 ? 161.981 121.171 174.074 1.00 60.76  ?  252 SER A O   1 
ATOM   1754  C  CB  . SER A 1 263 ? 160.153 123.521 172.770 1.00 60.76  ?  252 SER A CB  1 
ATOM   1755  O  OG  . SER A 1 263 ? 158.942 123.048 173.302 1.00 60.76  ?  252 SER A OG  1 
ATOM   1756  N  N   . GLN A 1 264 ? 160.072 120.365 173.226 1.00 62.14  ?  253 GLN A N   1 
ATOM   1757  C  CA  . GLN A 1 264 ? 159.970 119.230 174.126 1.00 62.14  ?  253 GLN A CA  1 
ATOM   1758  C  C   . GLN A 1 264 ? 160.283 117.914 173.447 1.00 62.14  ?  253 GLN A C   1 
ATOM   1759  O  O   . GLN A 1 264 ? 159.740 116.902 173.817 1.00 62.14  ?  253 GLN A O   1 
ATOM   1760  C  CB  . GLN A 1 264 ? 158.591 119.162 174.748 1.00 62.14  ?  253 GLN A CB  1 
ATOM   1761  C  CG  . GLN A 1 264 ? 157.519 118.849 173.750 1.00 62.14  ?  253 GLN A CG  1 
ATOM   1762  C  CD  . GLN A 1 264 ? 156.152 119.155 174.273 1.00 62.14  ?  253 GLN A CD  1 
ATOM   1763  O  OE1 . GLN A 1 264 ? 155.217 119.352 173.513 1.00 62.14  ?  253 GLN A OE1 1 
ATOM   1764  N  NE2 . GLN A 1 264 ? 156.024 119.190 175.579 1.00 62.14  ?  253 GLN A NE2 1 
ATOM   1765  N  N   . ILE A 1 265 ? 161.159 117.930 172.453 1.00 62.13  ?  254 ILE A N   1 
ATOM   1766  C  CA  . ILE A 1 265 ? 161.528 116.725 171.713 1.00 62.13  ?  254 ILE A CA  1 
ATOM   1767  C  C   . ILE A 1 265 ? 162.189 115.622 172.543 1.00 62.13  ?  254 ILE A C   1 
ATOM   1768  O  O   . ILE A 1 265 ? 162.107 114.470 172.179 1.00 62.13  ?  254 ILE A O   1 
ATOM   1769  C  CB  . ILE A 1 265 ? 162.369 117.024 170.460 1.00 62.13  ?  254 ILE A CB  1 
ATOM   1770  C  CG1 . ILE A 1 265 ? 162.384 115.811 169.533 1.00 62.13  ?  254 ILE A CG1 1 
ATOM   1771  C  CG2 . ILE A 1 265 ? 163.784 117.424 170.831 1.00 62.13  ?  254 ILE A CG2 1 
ATOM   1772  C  CD1 . ILE A 1 265 ? 161.103 115.607 168.757 1.00 62.13  ?  254 ILE A CD1 1 
ATOM   1773  N  N   . GLU A 1 266 ? 162.864 115.963 173.637 1.00 64.54  ?  255 GLU A N   1 
ATOM   1774  C  CA  . GLU A 1 266 ? 163.501 114.976 174.523 1.00 64.54  ?  255 GLU A CA  1 
ATOM   1775  C  C   . GLU A 1 266 ? 162.529 114.040 175.279 1.00 64.54  ?  255 GLU A C   1 
ATOM   1776  O  O   . GLU A 1 266 ? 162.924 112.975 175.731 1.00 64.54  ?  255 GLU A O   1 
ATOM   1777  C  CB  . GLU A 1 266 ? 164.496 115.637 175.479 1.00 64.54  ?  255 GLU A CB  1 
ATOM   1778  C  CG  . GLU A 1 266 ? 163.869 116.464 176.584 1.00 64.54  ?  255 GLU A CG  1 
ATOM   1779  C  CD  . GLU A 1 266 ? 163.142 117.675 176.052 1.00 64.54  ?  255 GLU A CD  1 
ATOM   1780  O  OE1 . GLU A 1 266 ? 163.338 118.002 174.868 1.00 64.54  ?  255 GLU A OE1 1 
ATOM   1781  O  OE2 . GLU A 1 266 ? 162.375 118.295 176.817 1.00 64.54  -1 255 GLU A OE2 1 
ATOM   1782  N  N   . LYS A 1 267 ? 161.263 114.439 175.405 1.00 64.51  ?  256 LYS A N   1 
ATOM   1783  C  CA  . LYS A 1 267 ? 160.203 113.666 176.059 1.00 64.51  ?  256 LYS A CA  1 
ATOM   1784  C  C   . LYS A 1 267 ? 159.546 112.630 175.139 1.00 64.51  ?  256 LYS A C   1 
ATOM   1785  O  O   . LYS A 1 267 ? 158.620 111.945 175.539 1.00 64.51  ?  256 LYS A O   1 
ATOM   1786  C  CB  . LYS A 1 267 ? 159.092 114.587 176.536 1.00 64.51  ?  256 LYS A CB  1 
ATOM   1787  C  CG  . LYS A 1 267 ? 159.469 115.605 177.581 1.00 64.51  ?  256 LYS A CG  1 
ATOM   1788  C  CD  . LYS A 1 267 ? 158.219 116.339 178.028 1.00 64.51  ?  256 LYS A CD  1 
ATOM   1789  C  CE  . LYS A 1 267 ? 158.508 117.788 178.365 1.00 64.51  ?  256 LYS A CE  1 
ATOM   1790  N  NZ  . LYS A 1 267 ? 157.263 118.596 178.357 1.00 64.51  1  256 LYS A NZ  1 
ATOM   1791  N  N   . THR A 1 268 ? 160.025 112.535 173.908 1.00 62.95  ?  257 THR A N   1 
ATOM   1792  C  CA  . THR A 1 268 ? 159.509 111.646 172.893 1.00 62.95  ?  257 THR A CA  1 
ATOM   1793  C  C   . THR A 1 268 ? 159.520 110.204 173.334 1.00 62.95  ?  257 THR A C   1 
ATOM   1794  O  O   . THR A 1 268 ? 160.485 109.743 173.914 1.00 62.95  ?  257 THR A O   1 
ATOM   1795  C  CB  . THR A 1 268 ? 160.428 111.773 171.662 1.00 62.95  ?  257 THR A CB  1 
ATOM   1796  O  OG1 . THR A 1 268 ? 160.278 113.078 171.102 1.00 62.95  ?  257 THR A OG1 1 
ATOM   1797  C  CG2 . THR A 1 268 ? 160.145 110.734 170.599 1.00 62.95  ?  257 THR A CG2 1 
ATOM   1798  N  N   . ASN A 1 269 ? 158.430 109.496 173.055 1.00 62.31  ?  258 ASN A N   1 
ATOM   1799  C  CA  . ASN A 1 269 ? 158.316 108.091 173.377 1.00 62.31  ?  258 ASN A CA  1 
ATOM   1800  C  C   . ASN A 1 269 ? 159.001 107.351 172.246 1.00 62.31  ?  258 ASN A C   1 
ATOM   1801  O  O   . ASN A 1 269 ? 158.612 107.481 171.104 1.00 62.31  ?  258 ASN A O   1 
ATOM   1802  C  CB  . ASN A 1 269 ? 156.838 107.714 173.439 1.00 62.31  ?  258 ASN A CB  1 
ATOM   1803  C  CG  . ASN A 1 269 ? 156.603 106.334 174.001 1.00 62.31  ?  258 ASN A CG  1 
ATOM   1804  O  OD1 . ASN A 1 269 ? 156.728 105.347 173.304 1.00 62.31  ?  258 ASN A OD1 1 
ATOM   1805  N  ND2 . ASN A 1 269 ? 156.236 106.267 175.263 1.00 62.31  ?  258 ASN A ND2 1 
ATOM   1806  N  N   . ILE A 1 270 ? 160.050 106.608 172.561 1.00 62.98  ?  259 ILE A N   1 
ATOM   1807  C  CA  . ILE A 1 270 ? 160.798 105.867 171.553 1.00 62.98  ?  259 ILE A CA  1 
ATOM   1808  C  C   . ILE A 1 270 ? 160.030 104.752 170.892 1.00 62.98  ?  259 ILE A C   1 
ATOM   1809  O  O   . ILE A 1 270 ? 160.152 104.524 169.701 1.00 62.98  ?  259 ILE A O   1 
ATOM   1810  C  CB  . ILE A 1 270 ? 162.116 105.306 172.112 1.00 62.98  ?  259 ILE A CB  1 
ATOM   1811  C  CG1 . ILE A 1 270 ? 163.023 106.451 172.531 1.00 62.98  ?  259 ILE A CG1 1 
ATOM   1812  C  CG2 . ILE A 1 270 ? 162.824 104.464 171.069 1.00 62.98  ?  259 ILE A CG2 1 
ATOM   1813  C  CD1 . ILE A 1 270 ? 163.165 107.497 171.456 1.00 62.98  ?  259 ILE A CD1 1 
ATOM   1814  N  N   . ALA A 1 271 ? 159.244 104.042 171.689 1.00 63.74  ?  260 ALA A N   1 
ATOM   1815  C  CA  . ALA A 1 271 ? 158.463 102.929 171.198 1.00 63.74  ?  260 ALA A CA  1 
ATOM   1816  C  C   . ALA A 1 271 ? 157.457 103.402 170.169 1.00 63.74  ?  260 ALA A C   1 
ATOM   1817  O  O   . ALA A 1 271 ? 157.218 102.715 169.190 1.00 63.74  ?  260 ALA A O   1 
ATOM   1818  C  CB  . ALA A 1 271 ? 157.778 102.232 172.344 1.00 63.74  ?  260 ALA A CB  1 
ATOM   1819  N  N   . ASP A 1 272 ? 156.830 104.548 170.413 1.00 62.35  ?  261 ASP A N   1 
ATOM   1820  C  CA  . ASP A 1 272 ? 155.891 105.112 169.461 1.00 62.35  ?  261 ASP A CA  1 
ATOM   1821  C  C   . ASP A 1 272 ? 156.565 105.500 168.171 1.00 62.35  ?  261 ASP A C   1 
ATOM   1822  O  O   . ASP A 1 272 ? 156.056 105.239 167.096 1.00 62.35  ?  261 ASP A O   1 
ATOM   1823  C  CB  . ASP A 1 272 ? 155.215 106.342 170.043 1.00 62.35  ?  261 ASP A CB  1 
ATOM   1824  C  CG  . ASP A 1 272 ? 153.948 106.006 170.768 1.00 62.35  ?  261 ASP A CG  1 
ATOM   1825  O  OD1 . ASP A 1 272 ? 153.611 106.689 171.747 1.00 62.35  ?  261 ASP A OD1 1 
ATOM   1826  O  OD2 . ASP A 1 272 ? 153.290 105.037 170.361 1.00 62.35  -1 261 ASP A OD2 1 
ATOM   1827  N  N   . LEU A 1 273 ? 157.718 106.136 168.290 1.00 61.81  ?  262 LEU A N   1 
ATOM   1828  C  CA  . LEU A 1 273 ? 158.479 106.584 167.141 1.00 61.81  ?  262 LEU A CA  1 
ATOM   1829  C  C   . LEU A 1 273 ? 158.987 105.449 166.277 1.00 61.81  ?  262 LEU A C   1 
ATOM   1830  O  O   . LEU A 1 273 ? 158.907 105.516 165.065 1.00 61.81  ?  262 LEU A O   1 
ATOM   1831  C  CB  . LEU A 1 273 ? 159.652 107.434 167.609 1.00 61.81  ?  262 LEU A CB  1 
ATOM   1832  C  CG  . LEU A 1 273 ? 160.653 107.924 166.564 1.00 61.81  ?  262 LEU A CG  1 
ATOM   1833  C  CD1 . LEU A 1 273 ? 160.079 109.042 165.718 1.00 61.81  ?  262 LEU A CD1 1 
ATOM   1834  C  CD2 . LEU A 1 273 ? 161.915 108.386 167.254 1.00 61.81  ?  262 LEU A CD2 1 
ATOM   1835  N  N   . VAL A 1 274 ? 159.509 104.407 166.900 1.00 62.03  ?  263 VAL A N   1 
ATOM   1836  C  CA  . VAL A 1 274 ? 160.027 103.280 166.146 1.00 62.03  ?  263 VAL A CA  1 
ATOM   1837  C  C   . VAL A 1 274 ? 158.930 102.568 165.385 1.00 62.03  ?  263 VAL A C   1 
ATOM   1838  O  O   . VAL A 1 274 ? 159.098 102.225 164.233 1.00 62.03  ?  263 VAL A O   1 
ATOM   1839  C  CB  . VAL A 1 274 ? 160.785 102.288 167.039 1.00 62.03  ?  263 VAL A CB  1 
ATOM   1840  C  CG1 . VAL A 1 274 ? 161.161 101.045 166.255 1.00 62.03  ?  263 VAL A CG1 1 
ATOM   1841  C  CG2 . VAL A 1 274 ? 162.025 102.947 167.613 1.00 62.03  ?  263 VAL A CG2 1 
ATOM   1842  N  N   . THR A 1 275 ? 157.791 102.379 166.034 1.00 63.13  ?  264 THR A N   1 
ATOM   1843  C  CA  . THR A 1 275 ? 156.662 101.710 165.420 1.00 63.13  ?  264 THR A CA  1 
ATOM   1844  C  C   . THR A 1 275 ? 156.162 102.501 164.243 1.00 63.13  ?  264 THR A C   1 
ATOM   1845  O  O   . THR A 1 275 ? 155.827 101.942 163.211 1.00 63.13  ?  264 THR A O   1 
ATOM   1846  C  CB  . THR A 1 275 ? 155.498 101.590 166.403 1.00 63.13  ?  264 THR A CB  1 
ATOM   1847  O  OG1 . THR A 1 275 ? 155.987 101.114 167.655 1.00 63.13  ?  264 THR A OG1 1 
ATOM   1848  C  CG2 . THR A 1 275 ? 154.462 100.633 165.873 1.00 63.13  ?  264 THR A CG2 1 
ATOM   1849  N  N   . ALA A 1 276 ? 156.088 103.810 164.417 1.00 61.88  ?  265 ALA A N   1 
ATOM   1850  C  CA  . ALA A 1 276 ? 155.642 104.687 163.367 1.00 61.88  ?  265 ALA A CA  1 
ATOM   1851  C  C   . ALA A 1 276 ? 156.600 104.641 162.198 1.00 61.88  ?  265 ALA A C   1 
ATOM   1852  O  O   . ALA A 1 276 ? 156.175 104.598 161.068 1.00 61.88  ?  265 ALA A O   1 
ATOM   1853  C  CB  . ALA A 1 276 ? 155.518 106.104 163.893 1.00 61.88  ?  265 ALA A CB  1 
ATOM   1854  N  N   . LEU A 1 277 ? 157.899 104.651 162.467 1.00 62.57  ?  266 LEU A N   1 
ATOM   1855  C  CA  . LEU A 1 277 ? 158.884 104.619 161.396 1.00 62.57  ?  266 LEU A CA  1 
ATOM   1856  C  C   . LEU A 1 277 ? 158.842 103.340 160.598 1.00 62.57  ?  266 LEU A C   1 
ATOM   1857  O  O   . LEU A 1 277 ? 158.918 103.365 159.385 1.00 62.57  ?  266 LEU A O   1 
ATOM   1858  C  CB  . LEU A 1 277 ? 160.287 104.832 161.952 1.00 62.57  ?  266 LEU A CB  1 
ATOM   1859  C  CG  . LEU A 1 277 ? 160.637 106.268 162.327 1.00 62.57  ?  266 LEU A CG  1 
ATOM   1860  C  CD1 . LEU A 1 277 ? 162.077 106.342 162.793 1.00 62.57  ?  266 LEU A CD1 1 
ATOM   1861  C  CD2 . LEU A 1 277 ? 160.386 107.212 161.165 1.00 62.57  ?  266 LEU A CD2 1 
ATOM   1862  N  N   . ILE A 1 278 ? 158.724 102.220 161.293 1.00 63.24  ?  267 ILE A N   1 
ATOM   1863  C  CA  . ILE A 1 278 ? 158.663 100.929 160.645 1.00 63.24  ?  267 ILE A CA  1 
ATOM   1864  C  C   . ILE A 1 278 ? 157.426 100.787 159.788 1.00 63.24  ?  267 ILE A C   1 
ATOM   1865  O  O   . ILE A 1 278 ? 157.493 100.281 158.679 1.00 63.24  ?  267 ILE A O   1 
ATOM   1866  C  CB  . ILE A 1 278 ? 158.672 99.808  161.682 1.00 63.24  ?  267 ILE A CB  1 
ATOM   1867  C  CG1 . ILE A 1 278 ? 160.060 99.676  162.292 1.00 63.24  ?  267 ILE A CG1 1 
ATOM   1868  C  CG2 . ILE A 1 278 ? 158.226 98.504  161.053 1.00 63.24  ?  267 ILE A CG2 1 
ATOM   1869  C  CD1 . ILE A 1 278 ? 160.057 99.005  163.641 1.00 63.24  ?  267 ILE A CD1 1 
ATOM   1870  N  N   . VAL A 1 279 ? 156.288 101.220 160.307 1.00 62.98  ?  268 VAL A N   1 
ATOM   1871  C  CA  . VAL A 1 279 ? 155.059 101.137 159.545 1.00 62.98  ?  268 VAL A CA  1 
ATOM   1872  C  C   . VAL A 1 279 ? 155.122 102.025 158.326 1.00 62.98  ?  268 VAL A C   1 
ATOM   1873  O  O   . VAL A 1 279 ? 154.712 101.636 157.249 1.00 62.98  ?  268 VAL A O   1 
ATOM   1874  C  CB  . VAL A 1 279 ? 153.830 101.511 160.395 1.00 62.98  ?  268 VAL A CB  1 
ATOM   1875  C  CG1 . VAL A 1 279 ? 152.682 101.950 159.504 1.00 62.98  ?  268 VAL A CG1 1 
ATOM   1876  C  CG2 . VAL A 1 279 ? 153.417 100.340 161.266 1.00 62.98  ?  268 VAL A CG2 1 
ATOM   1877  N  N   . LEU A 1 280 ? 155.633 103.231 158.512 1.00 63.64  ?  269 LEU A N   1 
ATOM   1878  C  CA  . LEU A 1 280 ? 155.757 104.191 157.431 1.00 63.64  ?  269 LEU A CA  1 
ATOM   1879  C  C   . LEU A 1 280 ? 156.730 103.713 156.364 1.00 63.64  ?  269 LEU A C   1 
ATOM   1880  O  O   . LEU A 1 280 ? 156.481 103.857 155.183 1.00 63.64  ?  269 LEU A O   1 
ATOM   1881  C  CB  . LEU A 1 280 ? 156.184 105.542 157.994 1.00 63.64  ?  269 LEU A CB  1 
ATOM   1882  C  CG  . LEU A 1 280 ? 156.502 106.706 157.068 1.00 63.64  ?  269 LEU A CG  1 
ATOM   1883  C  CD1 . LEU A 1 280 ? 155.256 107.135 156.326 1.00 63.64  ?  269 LEU A CD1 1 
ATOM   1884  C  CD2 . LEU A 1 280 ? 157.040 107.853 157.893 1.00 63.64  ?  269 LEU A CD2 1 
ATOM   1885  N  N   . LEU A 1 281 ? 157.853 103.159 156.790 1.00 66.24  ?  270 LEU A N   1 
ATOM   1886  C  CA  . LEU A 1 281 ? 158.838 102.654 155.857 1.00 66.24  ?  270 LEU A CA  1 
ATOM   1887  C  C   . LEU A 1 281 ? 158.317 101.487 155.044 1.00 66.24  ?  270 LEU A C   1 
ATOM   1888  O  O   . LEU A 1 281 ? 158.483 101.442 153.838 1.00 66.24  ?  270 LEU A O   1 
ATOM   1889  C  CB  . LEU A 1 281 ? 160.080 102.203 156.618 1.00 66.24  ?  270 LEU A CB  1 
ATOM   1890  C  CG  . LEU A 1 281 ? 161.061 101.343 155.827 1.00 66.24  ?  270 LEU A CG  1 
ATOM   1891  C  CD1 . LEU A 1 281 ? 162.096 102.226 155.150 1.00 66.24  ?  270 LEU A CD1 1 
ATOM   1892  C  CD2 . LEU A 1 281 ? 161.730 100.317 156.725 1.00 66.24  ?  270 LEU A CD2 1 
ATOM   1893  N  N   . VAL A 1 282 ? 157.678 100.541 155.716 1.00 66.66  ?  271 VAL A N   1 
ATOM   1894  C  CA  . VAL A 1 282 ? 157.130 99.376  155.047 1.00 66.66  ?  271 VAL A CA  1 
ATOM   1895  C  C   . VAL A 1 282 ? 155.986 99.687  154.112 1.00 66.66  ?  271 VAL A C   1 
ATOM   1896  O  O   . VAL A 1 282 ? 155.930 99.177  153.007 1.00 66.66  ?  271 VAL A O   1 
ATOM   1897  C  CB  . VAL A 1 282 ? 156.635 98.335  156.053 1.00 66.66  ?  271 VAL A CB  1 
ATOM   1898  C  CG1 . VAL A 1 282 ? 155.747 97.323  155.363 1.00 66.66  ?  271 VAL A CG1 1 
ATOM   1899  C  CG2 . VAL A 1 282 ? 157.808 97.657  156.721 1.00 66.66  ?  271 VAL A CG2 1 
ATOM   1900  N  N   . VAL A 1 283 ? 155.074 100.541 154.550 1.00 68.26  ?  272 VAL A N   1 
ATOM   1901  C  CA  . VAL A 1 283 ? 153.931 100.858 153.727 1.00 68.26  ?  272 VAL A CA  1 
ATOM   1902  C  C   . VAL A 1 283 ? 154.350 101.537 152.446 1.00 68.26  ?  272 VAL A C   1 
ATOM   1903  O  O   . VAL A 1 283 ? 153.856 101.204 151.387 1.00 68.26  ?  272 VAL A O   1 
ATOM   1904  C  CB  . VAL A 1 283 ? 152.890 101.699 154.487 1.00 68.26  ?  272 VAL A CB  1 
ATOM   1905  C  CG1 . VAL A 1 283 ? 152.019 102.475 153.520 1.00 68.26  ?  272 VAL A CG1 1 
ATOM   1906  C  CG2 . VAL A 1 283 ? 152.033 100.798 155.354 1.00 68.26  ?  272 VAL A CG2 1 
ATOM   1907  N  N   . SER A 1 284 ? 155.281 102.470 152.540 1.00 71.30  ?  273 SER A N   1 
ATOM   1908  C  CA  . SER A 1 284 ? 155.764 103.180 151.367 1.00 71.30  ?  273 SER A CA  1 
ATOM   1909  C  C   . SER A 1 284 ? 156.474 102.268 150.379 1.00 71.30  ?  273 SER A C   1 
ATOM   1910  O  O   . SER A 1 284 ? 156.308 102.414 149.180 1.00 71.30  ?  273 SER A O   1 
ATOM   1911  C  CB  . SER A 1 284 ? 156.704 104.298 151.781 1.00 71.30  ?  273 SER A CB  1 
ATOM   1912  O  OG  . SER A 1 284 ? 157.970 103.757 152.077 1.00 71.30  ?  273 SER A OG  1 
ATOM   1913  N  N   . ILE A 1 285 ? 157.293 101.346 150.871 1.00 73.88  ?  274 ILE A N   1 
ATOM   1914  C  CA  . ILE A 1 285 ? 157.989 100.446 149.975 1.00 73.88  ?  274 ILE A CA  1 
ATOM   1915  C  C   . ILE A 1 285 ? 157.000 99.575  149.224 1.00 73.88  ?  274 ILE A C   1 
ATOM   1916  O  O   . ILE A 1 285 ? 157.100 99.400  148.020 1.00 73.88  ?  274 ILE A O   1 
ATOM   1917  C  CB  . ILE A 1 285 ? 158.933 99.519  150.750 1.00 73.88  ?  274 ILE A CB  1 
ATOM   1918  C  CG1 . ILE A 1 285 ? 160.166 100.275 151.220 1.00 73.88  ?  274 ILE A CG1 1 
ATOM   1919  C  CG2 . ILE A 1 285 ? 159.351 98.346  149.887 1.00 73.88  ?  274 ILE A CG2 1 
ATOM   1920  C  CD1 . ILE A 1 285 ? 161.076 99.438  152.084 1.00 73.88  ?  274 ILE A CD1 1 
ATOM   1921  N  N   . VAL A 1 286 ? 156.038 99.026  149.948 1.00 74.81  ?  275 VAL A N   1 
ATOM   1922  C  CA  . VAL A 1 286 ? 155.010 98.200  149.351 1.00 74.81  ?  275 VAL A CA  1 
ATOM   1923  C  C   . VAL A 1 286 ? 154.073 98.989  148.448 1.00 74.81  ?  275 VAL A C   1 
ATOM   1924  O  O   . VAL A 1 286 ? 153.607 98.470  147.454 1.00 74.81  ?  275 VAL A O   1 
ATOM   1925  C  CB  . VAL A 1 286 ? 154.263 97.336  150.379 1.00 74.81  ?  275 VAL A CB  1 
ATOM   1926  C  CG1 . VAL A 1 286 ? 153.147 96.564  149.702 1.00 74.81  ?  275 VAL A CG1 1 
ATOM   1927  C  CG2 . VAL A 1 286 ? 155.230 96.370  151.034 1.00 74.81  ?  275 VAL A CG2 1 
ATOM   1928  N  N   . LYS A 1 287 ? 153.768 100.229 148.818 1.00 74.91  ?  276 LYS A N   1 
ATOM   1929  C  CA  . LYS A 1 287 ? 152.872 101.058 148.014 1.00 74.91  ?  276 LYS A CA  1 
ATOM   1930  C  C   . LYS A 1 287 ? 153.440 101.304 146.637 1.00 74.91  ?  276 LYS A C   1 
ATOM   1931  O  O   . LYS A 1 287 ? 152.708 101.310 145.657 1.00 74.91  ?  276 LYS A O   1 
ATOM   1932  C  CB  . LYS A 1 287 ? 152.588 102.400 148.684 1.00 74.91  ?  276 LYS A CB  1 
ATOM   1933  C  CG  . LYS A 1 287 ? 151.206 102.505 149.291 1.00 74.91  ?  276 LYS A CG  1 
ATOM   1934  C  CD  . LYS A 1 287 ? 151.034 103.789 150.080 1.00 74.91  ?  276 LYS A CD  1 
ATOM   1935  C  CE  . LYS A 1 287 ? 149.624 104.335 149.926 1.00 74.91  ?  276 LYS A CE  1 
ATOM   1936  N  NZ  . LYS A 1 287 ? 149.186 105.155 151.085 1.00 74.91  1  276 LYS A NZ  1 
ATOM   1937  N  N   . GLU A 1 288 ? 154.741 101.554 146.564 1.00 81.53  ?  277 GLU A N   1 
ATOM   1938  C  CA  . GLU A 1 288 ? 155.390 101.770 145.281 1.00 81.53  ?  277 GLU A CA  1 
ATOM   1939  C  C   . GLU A 1 288 ? 155.353 100.502 144.431 1.00 81.53  ?  277 GLU A C   1 
ATOM   1940  O  O   . GLU A 1 288 ? 155.149 100.568 143.230 1.00 81.53  ?  277 GLU A O   1 
ATOM   1941  C  CB  . GLU A 1 288 ? 156.790 102.376 145.419 1.00 81.53  ?  277 GLU A CB  1 
ATOM   1942  C  CG  . GLU A 1 288 ? 157.929 101.405 145.645 1.00 81.53  ?  277 GLU A CG  1 
ATOM   1943  C  CD  . GLU A 1 288 ? 159.226 102.124 145.950 1.00 81.53  ?  277 GLU A CD  1 
ATOM   1944  O  OE1 . GLU A 1 288 ? 159.157 103.257 146.471 1.00 81.53  ?  277 GLU A OE1 1 
ATOM   1945  O  OE2 . GLU A 1 288 ? 160.305 101.557 145.669 1.00 81.53  -1 277 GLU A OE2 1 
ATOM   1946  N  N   . ILE A 1 289 ? 155.496 99.342  145.068 1.00 82.18  ?  278 ILE A N   1 
ATOM   1947  C  CA  . ILE A 1 289 ? 155.475 98.065  144.370 1.00 82.18  ?  278 ILE A CA  1 
ATOM   1948  C  C   . ILE A 1 289 ? 154.140 97.848  143.670 1.00 82.18  ?  278 ILE A C   1 
ATOM   1949  O  O   . ILE A 1 289 ? 154.091 97.303  142.579 1.00 82.18  ?  278 ILE A O   1 
ATOM   1950  C  CB  . ILE A 1 289 ? 155.748 96.901  145.330 1.00 82.18  ?  278 ILE A CB  1 
ATOM   1951  C  CG1 . ILE A 1 289 ? 157.194 96.946  145.807 1.00 82.18  ?  278 ILE A CG1 1 
ATOM   1952  C  CG2 . ILE A 1 289 ? 155.452 95.571  144.661 1.00 82.18  ?  278 ILE A CG2 1 
ATOM   1953  C  CD1 . ILE A 1 289 ? 157.528 95.883  146.822 1.00 82.18  ?  278 ILE A CD1 1 
ATOM   1954  N  N   . ASN A 1 290 ? 153.049 98.235  144.312 1.00 85.13  ?  279 ASN A N   1 
ATOM   1955  C  CA  . ASN A 1 290 ? 151.753 98.106  143.690 1.00 85.13  ?  279 ASN A CA  1 
ATOM   1956  C  C   . ASN A 1 290 ? 151.654 98.964  142.440 1.00 85.13  ?  279 ASN A C   1 
ATOM   1957  O  O   . ASN A 1 290 ? 151.127 98.522  141.427 1.00 85.13  ?  279 ASN A O   1 
ATOM   1958  C  CB  . ASN A 1 290 ? 150.671 98.496  144.681 1.00 85.13  ?  279 ASN A CB  1 
ATOM   1959  C  CG  . ASN A 1 290 ? 150.652 97.593  145.877 1.00 85.13  ?  279 ASN A CG  1 
ATOM   1960  O  OD1 . ASN A 1 290 ? 149.985 97.866  146.861 1.00 85.13  ?  279 ASN A OD1 1 
ATOM   1961  N  ND2 . ASN A 1 290 ? 151.397 96.505  145.798 1.00 85.13  ?  279 ASN A ND2 1 
ATOM   1962  N  N   . GLN A 1 291 ? 152.136 100.199 142.508 1.00 88.50  ?  280 GLN A N   1 
ATOM   1963  C  CA  . GLN A 1 291 ? 152.117 101.061 141.331 1.00 88.50  ?  280 GLN A CA  1 
ATOM   1964  C  C   . GLN A 1 291 ? 153.034 100.570 140.210 1.00 88.50  ?  280 GLN A C   1 
ATOM   1965  O  O   . GLN A 1 291 ? 152.662 100.596 139.042 1.00 88.50  ?  280 GLN A O   1 
ATOM   1966  C  CB  . GLN A 1 291 ? 152.445 102.505 141.702 1.00 88.50  ?  280 GLN A CB  1 
ATOM   1967  C  CG  . GLN A 1 291 ? 151.234 103.302 142.158 1.00 88.50  ?  280 GLN A CG  1 
ATOM   1968  C  CD  . GLN A 1 291 ? 151.613 104.541 142.941 1.00 88.50  ?  280 GLN A CD  1 
ATOM   1969  O  OE1 . GLN A 1 291 ? 152.497 105.300 142.540 1.00 88.50  ?  280 GLN A OE1 1 
ATOM   1970  N  NE2 . GLN A 1 291 ? 150.948 104.751 144.071 1.00 88.50  ?  280 GLN A NE2 1 
ATOM   1971  N  N   . ARG A 1 292 ? 154.243 100.144 140.556 1.00 91.31  ?  281 ARG A N   1 
ATOM   1972  C  CA  . ARG A 1 292 ? 155.169 99.652  139.541 1.00 91.31  ?  281 ARG A CA  1 
ATOM   1973  C  C   . ARG A 1 292 ? 154.771 98.337  138.870 1.00 91.31  ?  281 ARG A C   1 
ATOM   1974  O  O   . ARG A 1 292 ? 154.899 98.181  137.659 1.00 91.31  ?  281 ARG A O   1 
ATOM   1975  C  CB  . ARG A 1 292 ? 156.597 99.538  140.083 1.00 91.31  ?  281 ARG A CB  1 
ATOM   1976  C  CG  . ARG A 1 292 ? 157.153 100.796 140.728 1.00 91.31  ?  281 ARG A CG  1 
ATOM   1977  C  CD  . ARG A 1 292 ? 156.930 102.033 139.882 1.00 91.31  ?  281 ARG A CD  1 
ATOM   1978  N  NE  . ARG A 1 292 ? 157.211 103.244 140.646 1.00 91.31  ?  281 ARG A NE  1 
ATOM   1979  C  CZ  . ARG A 1 292 ? 157.558 104.406 140.106 1.00 91.31  ?  281 ARG A CZ  1 
ATOM   1980  N  NH1 . ARG A 1 292 ? 157.785 105.456 140.881 1.00 91.31  1  281 ARG A NH1 1 
ATOM   1981  N  NH2 . ARG A 1 292 ? 157.679 104.520 138.792 1.00 91.31  ?  281 ARG A NH2 1 
ATOM   1982  N  N   . PHE A 1 293 ? 154.267 97.403  139.668 1.00 92.45  ?  282 PHE A N   1 
ATOM   1983  C  CA  . PHE A 1 293 ? 153.934 96.063  139.190 1.00 92.45  ?  282 PHE A CA  1 
ATOM   1984  C  C   . PHE A 1 293 ? 152.453 95.750  139.055 1.00 92.45  ?  282 PHE A C   1 
ATOM   1985  O  O   . PHE A 1 293 ? 152.015 94.671  139.434 1.00 92.45  ?  282 PHE A O   1 
ATOM   1986  C  CB  . PHE A 1 293 ? 154.589 94.999  140.073 1.00 92.45  ?  282 PHE A CB  1 
ATOM   1987  C  CG  . PHE A 1 293 ? 156.081 95.082  140.117 1.00 92.45  ?  282 PHE A CG  1 
ATOM   1988  C  CD1 . PHE A 1 293 ? 156.708 96.192  140.645 1.00 92.45  ?  282 PHE A CD1 1 
ATOM   1989  C  CD2 . PHE A 1 293 ? 156.860 94.038  139.657 1.00 92.45  ?  282 PHE A CD2 1 
ATOM   1990  C  CE1 . PHE A 1 293 ? 158.084 96.279  140.693 1.00 92.45  ?  282 PHE A CE1 1 
ATOM   1991  C  CE2 . PHE A 1 293 ? 158.238 94.112  139.702 1.00 92.45  ?  282 PHE A CE2 1 
ATOM   1992  C  CZ  . PHE A 1 293 ? 158.852 95.234  140.224 1.00 92.45  ?  282 PHE A CZ  1 
ATOM   1993  N  N   . LYS A 1 294 ? 151.681 96.679  138.516 1.00 94.07  ?  283 LYS A N   1 
ATOM   1994  C  CA  . LYS A 1 294 ? 150.250 96.446  138.376 1.00 94.07  ?  283 LYS A CA  1 
ATOM   1995  C  C   . LYS A 1 294 ? 149.958 95.226  137.509 1.00 94.07  ?  283 LYS A C   1 
ATOM   1996  O  O   . LYS A 1 294 ? 149.064 94.450  137.824 1.00 94.07  ?  283 LYS A O   1 
ATOM   1997  C  CB  . LYS A 1 294 ? 149.578 97.665  137.753 1.00 94.07  ?  283 LYS A CB  1 
ATOM   1998  C  CG  . LYS A 1 294 ? 149.605 98.909  138.617 1.00 94.07  ?  283 LYS A CG  1 
ATOM   1999  C  CD  . LYS A 1 294 ? 148.478 98.871  139.632 1.00 94.07  ?  283 LYS A CD  1 
ATOM   2000  C  CE  . LYS A 1 294 ? 147.125 98.851  138.949 1.00 94.07  ?  283 LYS A CE  1 
ATOM   2001  N  NZ  . LYS A 1 294 ? 146.854 100.134 138.251 1.00 94.07  1  283 LYS A NZ  1 
ATOM   2002  N  N   . ASP A 1 295 ? 150.672 95.065  136.401 1.00 98.41  ?  284 ASP A N   1 
ATOM   2003  C  CA  . ASP A 1 295 ? 150.453 93.900  135.548 1.00 98.41  ?  284 ASP A CA  1 
ATOM   2004  C  C   . ASP A 1 295 ? 150.843 92.571  136.201 1.00 98.41  ?  284 ASP A C   1 
ATOM   2005  O  O   . ASP A 1 295 ? 150.110 91.586  136.120 1.00 98.41  ?  284 ASP A O   1 
ATOM   2006  C  CB  . ASP A 1 295 ? 151.186 94.062  134.219 1.00 98.41  ?  284 ASP A CB  1 
ATOM   2007  N  N   . LYS A 1 296 ? 151.989 92.558  136.868 1.00 97.95  ?  285 LYS A N   1 
ATOM   2008  C  CA  . LYS A 1 296 ? 152.500 91.358  137.519 1.00 97.95  ?  285 LYS A CA  1 
ATOM   2009  C  C   . LYS A 1 296 ? 151.609 90.857  138.646 1.00 97.95  ?  285 LYS A C   1 
ATOM   2010  O  O   . LYS A 1 296 ? 151.469 89.652  138.850 1.00 97.95  ?  285 LYS A O   1 
ATOM   2011  C  CB  . LYS A 1 296 ? 153.918 91.589  138.036 1.00 97.95  ?  285 LYS A CB  1 
ATOM   2012  N  N   . LEU A 1 297 ? 151.043 91.794  139.400 1.00 94.52  ?  286 LEU A N   1 
ATOM   2013  C  CA  . LEU A 1 297 ? 150.185 91.464  140.529 1.00 94.52  ?  286 LEU A CA  1 
ATOM   2014  C  C   . LEU A 1 297 ? 148.745 91.219  140.123 1.00 94.52  ?  286 LEU A C   1 
ATOM   2015  O  O   . LEU A 1 297 ? 148.164 91.996  139.370 1.00 94.52  ?  286 LEU A O   1 
ATOM   2016  C  CB  . LEU A 1 297 ? 150.250 92.575  141.578 1.00 94.52  ?  286 LEU A CB  1 
ATOM   2017  C  CG  . LEU A 1 297 ? 151.601 92.719  142.280 1.00 94.52  ?  286 LEU A CG  1 
ATOM   2018  C  CD1 . LEU A 1 297 ? 151.814 94.138  142.776 1.00 94.52  ?  286 LEU A CD1 1 
ATOM   2019  C  CD2 . LEU A 1 297 ? 151.750 91.707  143.405 1.00 94.52  ?  286 LEU A CD2 1 
ATOM   2020  N  N   . PRO A 1 298 ? 148.158 90.129  140.633 1.00 93.62  ?  287 PRO A N   1 
ATOM   2021  C  CA  . PRO A 1 298 ? 146.765 89.765  140.355 1.00 93.62  ?  287 PRO A CA  1 
ATOM   2022  C  C   . PRO A 1 298 ? 145.831 90.714  141.089 1.00 93.62  ?  287 PRO A C   1 
ATOM   2023  O  O   . PRO A 1 298 ? 144.731 91.012  140.632 1.00 93.62  ?  287 PRO A O   1 
ATOM   2024  C  CB  . PRO A 1 298 ? 146.650 88.353  140.926 1.00 93.62  ?  287 PRO A CB  1 
ATOM   2025  C  CG  . PRO A 1 298 ? 147.715 88.268  141.964 1.00 93.62  ?  287 PRO A CG  1 
ATOM   2026  C  CD  . PRO A 1 298 ? 148.833 89.157  141.507 1.00 93.62  ?  287 PRO A CD  1 
ATOM   2027  N  N   . VAL A 1 299 ? 146.286 91.173  142.244 1.00 90.44  ?  288 VAL A N   1 
ATOM   2028  C  CA  . VAL A 1 299 ? 145.547 92.116  143.059 1.00 90.44  ?  288 VAL A CA  1 
ATOM   2029  C  C   . VAL A 1 299 ? 146.591 92.807  143.911 1.00 90.44  ?  288 VAL A C   1 
ATOM   2030  O  O   . VAL A 1 299 ? 147.522 92.165  144.394 1.00 90.44  ?  288 VAL A O   1 
ATOM   2031  C  CB  . VAL A 1 299 ? 144.472 91.438  143.932 1.00 90.44  ?  288 VAL A CB  1 
ATOM   2032  C  CG1 . VAL A 1 299 ? 145.081 90.377  144.828 1.00 90.44  ?  288 VAL A CG1 1 
ATOM   2033  C  CG2 . VAL A 1 299 ? 143.725 92.474  144.750 1.00 90.44  ?  288 VAL A CG2 1 
ATOM   2034  N  N   . PRO A 1 300 ? 146.447 94.122  144.095 1.00 86.59  ?  289 PRO A N   1 
ATOM   2035  C  CA  . PRO A 1 300 ? 147.417 94.890  144.878 1.00 86.59  ?  289 PRO A CA  1 
ATOM   2036  C  C   . PRO A 1 300 ? 147.509 94.410  146.319 1.00 86.59  ?  289 PRO A C   1 
ATOM   2037  O  O   . PRO A 1 300 ? 146.508 93.999  146.899 1.00 86.59  ?  289 PRO A O   1 
ATOM   2038  C  CB  . PRO A 1 300 ? 146.849 96.307  144.833 1.00 86.59  ?  289 PRO A CB  1 
ATOM   2039  C  CG  . PRO A 1 300 ? 145.385 96.115  144.639 1.00 86.59  ?  289 PRO A CG  1 
ATOM   2040  C  CD  . PRO A 1 300 ? 145.254 94.912  143.759 1.00 86.59  ?  289 PRO A CD  1 
ATOM   2041  N  N   . ILE A 1 301 ? 148.708 94.459  146.885 1.00 80.82  ?  290 ILE A N   1 
ATOM   2042  C  CA  . ILE A 1 301 ? 148.910 94.060  148.266 1.00 80.82  ?  290 ILE A CA  1 
ATOM   2043  C  C   . ILE A 1 301 ? 148.284 95.110  149.171 1.00 80.82  ?  290 ILE A C   1 
ATOM   2044  O  O   . ILE A 1 301 ? 148.570 96.289  149.038 1.00 80.82  ?  290 ILE A O   1 
ATOM   2045  C  CB  . ILE A 1 301 ? 150.403 93.972  148.606 1.00 80.82  ?  290 ILE A CB  1 
ATOM   2046  C  CG1 . ILE A 1 301 ? 151.143 93.165  147.548 1.00 80.82  ?  290 ILE A CG1 1 
ATOM   2047  C  CG2 . ILE A 1 301 ? 150.600 93.353  149.979 1.00 80.82  ?  290 ILE A CG2 1 
ATOM   2048  C  CD1 . ILE A 1 301 ? 150.605 91.766  147.378 1.00 80.82  ?  290 ILE A CD1 1 
ATOM   2049  N  N   . PRO A 1 302 ? 147.415 94.694  150.095 1.00 75.33  ?  291 PRO A N   1 
ATOM   2050  C  CA  . PRO A 1 302 ? 146.823 95.698  150.979 1.00 75.33  ?  291 PRO A CA  1 
ATOM   2051  C  C   . PRO A 1 302 ? 147.744 95.928  152.166 1.00 75.33  ?  291 PRO A C   1 
ATOM   2052  O  O   . PRO A 1 302 ? 147.508 95.404  153.239 1.00 75.33  ?  291 PRO A O   1 
ATOM   2053  C  CB  . PRO A 1 302 ? 145.515 95.046  151.426 1.00 75.33  ?  291 PRO A CB  1 
ATOM   2054  C  CG  . PRO A 1 302 ? 145.631 93.599  151.079 1.00 75.33  ?  291 PRO A CG  1 
ATOM   2055  C  CD  . PRO A 1 302 ? 146.944 93.341  150.405 1.00 75.33  ?  291 PRO A CD  1 
ATOM   2056  N  N   . ILE A 1 303 ? 148.803 96.693  151.955 1.00 70.63  ?  292 ILE A N   1 
ATOM   2057  C  CA  . ILE A 1 303 ? 149.778 96.953  152.998 1.00 70.63  ?  292 ILE A CA  1 
ATOM   2058  C  C   . ILE A 1 303 ? 149.278 97.731  154.220 1.00 70.63  ?  292 ILE A C   1 
ATOM   2059  O  O   . ILE A 1 303 ? 149.669 97.425  155.335 1.00 70.63  ?  292 ILE A O   1 
ATOM   2060  C  CB  . ILE A 1 303 ? 151.099 97.512  152.419 1.00 70.63  ?  292 ILE A CB  1 
ATOM   2061  C  CG1 . ILE A 1 303 ? 152.244 97.263  153.393 1.00 70.63  ?  292 ILE A CG1 1 
ATOM   2062  C  CG2 . ILE A 1 303 ? 150.967 98.970  152.002 1.00 70.63  ?  292 ILE A CG2 1 
ATOM   2063  C  CD1 . ILE A 1 303 ? 152.311 95.834  153.875 1.00 70.63  ?  292 ILE A CD1 1 
ATOM   2064  N  N   . GLU A 1 304 ? 148.436 98.735  154.016 1.00 67.85  ?  293 GLU A N   1 
ATOM   2065  C  CA  . GLU A 1 304 ? 147.930 99.513  155.130 1.00 67.85  ?  293 GLU A CA  1 
ATOM   2066  C  C   . GLU A 1 304 ? 147.094 98.658  156.061 1.00 67.85  ?  293 GLU A C   1 
ATOM   2067  O  O   . GLU A 1 304 ? 147.159 98.810  157.267 1.00 67.85  ?  293 GLU A O   1 
ATOM   2068  C  CB  . GLU A 1 304 ? 147.111 100.702 154.644 1.00 67.85  ?  293 GLU A CB  1 
ATOM   2069  C  CG  . GLU A 1 304 ? 147.834 101.616 153.678 1.00 67.85  ?  293 GLU A CG  1 
ATOM   2070  C  CD  . GLU A 1 304 ? 147.769 101.111 152.258 1.00 67.85  ?  293 GLU A CD  1 
ATOM   2071  O  OE1 . GLU A 1 304 ? 148.203 101.834 151.354 1.00 67.85  ?  293 GLU A OE1 1 
ATOM   2072  O  OE2 . GLU A 1 304 ? 147.276 99.990  152.042 1.00 67.85  -1 293 GLU A OE2 1 
ATOM   2073  N  N   . PHE A 1 305 ? 146.256 97.799  155.500 1.00 66.48  ?  294 PHE A N   1 
ATOM   2074  C  CA  . PHE A 1 305 ? 145.447 96.916  156.317 1.00 66.48  ?  294 PHE A CA  1 
ATOM   2075  C  C   . PHE A 1 305 ? 146.302 95.893  157.050 1.00 66.48  ?  294 PHE A C   1 
ATOM   2076  O  O   . PHE A 1 305 ? 146.103 95.632  158.221 1.00 66.48  ?  294 PHE A O   1 
ATOM   2077  C  CB  . PHE A 1 305 ? 144.380 96.222  155.479 1.00 66.48  ?  294 PHE A CB  1 
ATOM   2078  C  CG  . PHE A 1 305 ? 143.446 95.378  156.280 1.00 66.48  ?  294 PHE A CG  1 
ATOM   2079  C  CD1 . PHE A 1 305 ? 142.589 95.954  157.193 1.00 66.48  ?  294 PHE A CD1 1 
ATOM   2080  C  CD2 . PHE A 1 305 ? 143.430 94.013  156.130 1.00 66.48  ?  294 PHE A CD2 1 
ATOM   2081  C  CE1 . PHE A 1 305 ? 141.725 95.182  157.937 1.00 66.48  ?  294 PHE A CE1 1 
ATOM   2082  C  CE2 . PHE A 1 305 ? 142.569 93.234  156.870 1.00 66.48  ?  294 PHE A CE2 1 
ATOM   2083  C  CZ  . PHE A 1 305 ? 141.712 93.822  157.772 1.00 66.48  ?  294 PHE A CZ  1 
ATOM   2084  N  N   . ILE A 1 306 ? 147.277 95.331  156.352 1.00 67.65  ?  295 ILE A N   1 
ATOM   2085  C  CA  . ILE A 1 306 ? 148.154 94.333  156.943 1.00 67.65  ?  295 ILE A CA  1 
ATOM   2086  C  C   . ILE A 1 306 ? 148.951 94.930  158.088 1.00 67.65  ?  295 ILE A C   1 
ATOM   2087  O  O   . ILE A 1 306 ? 149.141 94.292  159.107 1.00 67.65  ?  295 ILE A O   1 
ATOM   2088  C  CB  . ILE A 1 306 ? 149.104 93.735  155.899 1.00 67.65  ?  295 ILE A CB  1 
ATOM   2089  C  CG1 . ILE A 1 306 ? 148.352 92.734  155.024 1.00 67.65  ?  295 ILE A CG1 1 
ATOM   2090  C  CG2 . ILE A 1 306 ? 150.283 93.056  156.573 1.00 67.65  ?  295 ILE A CG2 1 
ATOM   2091  C  CD1 . ILE A 1 306 ? 149.132 92.271  153.818 1.00 67.65  ?  295 ILE A CD1 1 
ATOM   2092  N  N   . MET A 1 307 ? 149.422 96.156  157.909 1.00 67.52  ?  296 MET A N   1 
ATOM   2093  C  CA  . MET A 1 307 ? 150.185 96.829  158.939 1.00 67.52  ?  296 MET A CA  1 
ATOM   2094  C  C   . MET A 1 307 ? 149.391 97.088  160.202 1.00 67.52  ?  296 MET A C   1 
ATOM   2095  O  O   . MET A 1 307 ? 149.906 96.891  161.278 1.00 67.52  ?  296 MET A O   1 
ATOM   2096  C  CB  . MET A 1 307 ? 150.750 98.145  158.415 1.00 67.52  ?  296 MET A CB  1 
ATOM   2097  C  CG  . MET A 1 307 ? 152.013 97.995  157.587 1.00 67.52  ?  296 MET A CG  1 
ATOM   2098  S  SD  . MET A 1 307 ? 153.230 96.947  158.389 1.00 67.52  ?  296 MET A SD  1 
ATOM   2099  C  CE  . MET A 1 307 ? 152.944 95.396  157.562 1.00 67.52  ?  296 MET A CE  1 
ATOM   2100  N  N   . THR A 1 308 ? 148.151 97.547  160.081 1.00 63.93  ?  297 THR A N   1 
ATOM   2101  C  CA  . THR A 1 308 ? 147.337 97.803  161.263 1.00 63.93  ?  297 THR A CA  1 
ATOM   2102  C  C   . THR A 1 308 ? 146.995 96.558  162.039 1.00 63.93  ?  297 THR A C   1 
ATOM   2103  O  O   . THR A 1 308 ? 146.993 96.578  163.253 1.00 63.93  ?  297 THR A O   1 
ATOM   2104  C  CB  . THR A 1 308 ? 146.033 98.546  160.955 1.00 63.93  ?  297 THR A CB  1 
ATOM   2105  O  OG1 . THR A 1 308 ? 145.187 97.714  160.166 1.00 63.93  ?  297 THR A OG1 1 
ATOM   2106  C  CG2 . THR A 1 308 ? 146.314 99.786  160.212 1.00 63.93  ?  297 THR A CG2 1 
ATOM   2107  N  N   . VAL A 1 309 ? 146.661 95.484  161.341 1.00 63.85  ?  298 VAL A N   1 
ATOM   2108  C  CA  . VAL A 1 309 ? 146.319 94.245  162.016 1.00 63.85  ?  298 VAL A CA  1 
ATOM   2109  C  C   . VAL A 1 309 ? 147.528 93.727  162.772 1.00 63.85  ?  298 VAL A C   1 
ATOM   2110  O  O   . VAL A 1 309 ? 147.409 93.266  163.897 1.00 63.85  ?  298 VAL A O   1 
ATOM   2111  C  CB  . VAL A 1 309 ? 145.815 93.175  161.032 1.00 63.85  ?  298 VAL A CB  1 
ATOM   2112  C  CG1 . VAL A 1 309 ? 145.477 91.898  161.768 1.00 63.85  ?  298 VAL A CG1 1 
ATOM   2113  C  CG2 . VAL A 1 309 ? 144.598 93.674  160.285 1.00 63.85  ?  298 VAL A CG2 1 
ATOM   2114  N  N   . ILE A 1 310 ? 148.687 93.779  162.126 1.00 65.51  ?  299 ILE A N   1 
ATOM   2115  C  CA  . ILE A 1 310 ? 149.936 93.365  162.745 1.00 65.51  ?  299 ILE A CA  1 
ATOM   2116  C  C   . ILE A 1 310 ? 150.325 94.287  163.887 1.00 65.51  ?  299 ILE A C   1 
ATOM   2117  O  O   . ILE A 1 310 ? 150.787 93.834  164.916 1.00 65.51  ?  299 ILE A O   1 
ATOM   2118  C  CB  . ILE A 1 310 ? 151.096 93.335  161.742 1.00 65.51  ?  299 ILE A CB  1 
ATOM   2119  C  CG1 . ILE A 1 310 ? 150.931 92.185  160.757 1.00 65.51  ?  299 ILE A CG1 1 
ATOM   2120  C  CG2 . ILE A 1 310 ? 152.419 93.189  162.466 1.00 65.51  ?  299 ILE A CG2 1 
ATOM   2121  C  CD1 . ILE A 1 310 ? 152.176 91.931  159.949 1.00 65.51  ?  299 ILE A CD1 1 
ATOM   2122  N  N   . ALA A 1 311 ? 150.165 95.590  163.697 1.00 64.23  ?  300 ALA A N   1 
ATOM   2123  C  CA  . ALA A 1 311 ? 150.516 96.525  164.751 1.00 64.23  ?  300 ALA A CA  1 
ATOM   2124  C  C   . ALA A 1 311 ? 149.633 96.336  165.961 1.00 64.23  ?  300 ALA A C   1 
ATOM   2125  O  O   . ALA A 1 311 ? 150.107 96.368  167.077 1.00 64.23  ?  300 ALA A O   1 
ATOM   2126  C  CB  . ALA A 1 311 ? 150.440 97.955  164.260 1.00 64.23  ?  300 ALA A CB  1 
ATOM   2127  N  N   . ALA A 1 312 ? 148.340 96.170  165.730 1.00 63.56  ?  301 ALA A N   1 
ATOM   2128  C  CA  . ALA A 1 312 ? 147.382 95.965  166.799 1.00 63.56  ?  301 ALA A CA  1 
ATOM   2129  C  C   . ALA A 1 312 ? 147.606 94.647  167.510 1.00 63.56  ?  301 ALA A C   1 
ATOM   2130  O  O   . ALA A 1 312 ? 147.441 94.555  168.713 1.00 63.56  ?  301 ALA A O   1 
ATOM   2131  C  CB  . ALA A 1 312 ? 145.968 96.051  166.268 1.00 63.56  ?  301 ALA A CB  1 
ATOM   2132  N  N   . GLY A 1 313 ? 147.914 93.609  166.741 1.00 64.36  ?  302 GLY A N   1 
ATOM   2133  C  CA  . GLY A 1 313 ? 148.155 92.298  167.303 1.00 64.36  ?  302 GLY A CA  1 
ATOM   2134  C  C   . GLY A 1 313 ? 149.377 92.264  168.178 1.00 64.36  ?  302 GLY A C   1 
ATOM   2135  O  O   . GLY A 1 313 ? 149.369 91.673  169.241 1.00 64.36  ?  302 GLY A O   1 
ATOM   2136  N  N   . VAL A 1 314 ? 150.447 92.875  167.700 1.00 65.83  ?  303 VAL A N   1 
ATOM   2137  C  CA  . VAL A 1 314 ? 151.683 92.961  168.451 1.00 65.83  ?  303 VAL A CA  1 
ATOM   2138  C  C   . VAL A 1 314 ? 151.550 93.850  169.674 1.00 65.83  ?  303 VAL A C   1 
ATOM   2139  O  O   . VAL A 1 314 ? 152.086 93.552  170.723 1.00 65.83  ?  303 VAL A O   1 
ATOM   2140  C  CB  . VAL A 1 314 ? 152.854 93.413  167.573 1.00 65.83  ?  303 VAL A CB  1 
ATOM   2141  C  CG1 . VAL A 1 314 ? 154.075 93.665  168.429 1.00 65.83  ?  303 VAL A CG1 1 
ATOM   2142  C  CG2 . VAL A 1 314 ? 153.150 92.359  166.526 1.00 65.83  ?  303 VAL A CG2 1 
ATOM   2143  N  N   . SER A 1 315 ? 150.845 94.961  169.529 1.00 65.76  ?  304 SER A N   1 
ATOM   2144  C  CA  . SER A 1 315 ? 150.659 95.865  170.647 1.00 65.76  ?  304 SER A CA  1 
ATOM   2145  C  C   . SER A 1 315 ? 149.900 95.163  171.752 1.00 65.76  ?  304 SER A C   1 
ATOM   2146  O  O   . SER A 1 315 ? 150.230 95.296  172.915 1.00 65.76  ?  304 SER A O   1 
ATOM   2147  C  CB  . SER A 1 315 ? 149.878 97.091  170.206 1.00 65.76  ?  304 SER A CB  1 
ATOM   2148  O  OG  . SER A 1 315 ? 149.513 97.881  171.312 1.00 65.76  ?  304 SER A OG  1 
ATOM   2149  N  N   . TYR A 1 316 ? 148.850 94.449  171.376 1.00 66.44  ?  305 TYR A N   1 
ATOM   2150  C  CA  . TYR A 1 316 ? 148.058 93.685  172.314 1.00 66.44  ?  305 TYR A CA  1 
ATOM   2151  C  C   . TYR A 1 316 ? 148.821 92.503  172.893 1.00 66.44  ?  305 TYR A C   1 
ATOM   2152  O  O   . TYR A 1 316 ? 148.785 92.250  174.085 1.00 66.44  ?  305 TYR A O   1 
ATOM   2153  C  CB  . TYR A 1 316 ? 146.782 93.210  171.626 1.00 66.44  ?  305 TYR A CB  1 
ATOM   2154  C  CG  . TYR A 1 316 ? 145.895 92.369  172.496 1.00 66.44  ?  305 TYR A CG  1 
ATOM   2155  C  CD1 . TYR A 1 316 ? 145.723 91.026  172.241 1.00 66.44  ?  305 TYR A CD1 1 
ATOM   2156  C  CD2 . TYR A 1 316 ? 145.246 92.913  173.578 1.00 66.44  ?  305 TYR A CD2 1 
ATOM   2157  C  CE1 . TYR A 1 316 ? 144.920 90.247  173.038 1.00 66.44  ?  305 TYR A CE1 1 
ATOM   2158  C  CE2 . TYR A 1 316 ? 144.440 92.141  174.383 1.00 66.44  ?  305 TYR A CE2 1 
ATOM   2159  C  CZ  . TYR A 1 316 ? 144.285 90.806  174.103 1.00 66.44  ?  305 TYR A CZ  1 
ATOM   2160  O  OH  . TYR A 1 316 ? 143.480 90.025  174.887 1.00 66.44  ?  305 TYR A OH  1 
ATOM   2161  N  N   . GLY A 1 317 ? 149.531 91.795  172.030 1.00 69.02  ?  306 GLY A N   1 
ATOM   2162  C  CA  . GLY A 1 317 ? 150.290 90.625  172.419 1.00 69.02  ?  306 GLY A CA  1 
ATOM   2163  C  C   . GLY A 1 317 ? 151.421 90.884  173.378 1.00 69.02  ?  306 GLY A C   1 
ATOM   2164  O  O   . GLY A 1 317 ? 151.643 90.118  174.300 1.00 69.02  ?  306 GLY A O   1 
ATOM   2165  N  N   . CYS A 1 318 ? 152.141 91.972  173.153 1.00 71.41  ?  307 CYS A N   1 
ATOM   2166  C  CA  . CYS A 1 318 ? 153.275 92.340  173.982 1.00 71.41  ?  307 CYS A CA  1 
ATOM   2167  C  C   . CYS A 1 318 ? 152.924 93.378  175.034 1.00 71.41  ?  307 CYS A C   1 
ATOM   2168  O  O   . CYS A 1 318 ? 153.807 93.908  175.696 1.00 71.41  ?  307 CYS A O   1 
ATOM   2169  C  CB  . CYS A 1 318 ? 154.421 92.842  173.118 1.00 71.41  ?  307 CYS A CB  1 
ATOM   2170  S  SG  . CYS A 1 318 ? 154.827 91.773  171.728 1.00 71.41  ?  307 CYS A SG  1 
ATOM   2171  N  N   . ASP A 1 319 ? 151.639 93.693  175.146 1.00 73.17  ?  308 ASP A N   1 
ATOM   2172  C  CA  . ASP A 1 319 ? 151.144 94.655  176.123 1.00 73.17  ?  308 ASP A CA  1 
ATOM   2173  C  C   . ASP A 1 319 ? 151.892 95.966  176.052 1.00 73.17  ?  308 ASP A C   1 
ATOM   2174  O  O   . ASP A 1 319 ? 152.324 96.481  177.068 1.00 73.17  ?  308 ASP A O   1 
ATOM   2175  C  CB  . ASP A 1 319 ? 151.182 94.092  177.539 1.00 73.17  ?  308 ASP A CB  1 
ATOM   2176  C  CG  . ASP A 1 319 ? 150.226 94.804  178.471 1.00 73.17  ?  308 ASP A CG  1 
ATOM   2177  O  OD1 . ASP A 1 319 ? 149.514 95.724  178.015 1.00 73.17  ?  308 ASP A OD1 1 
ATOM   2178  O  OD2 . ASP A 1 319 ? 150.180 94.436  179.662 1.00 73.17  -1 308 ASP A OD2 1 
ATOM   2179  N  N   . PHE A 1 320 ? 151.990 96.528  174.855 1.00 69.15  ?  309 PHE A N   1 
ATOM   2180  C  CA  . PHE A 1 320 ? 152.738 97.755  174.618 1.00 69.15  ?  309 PHE A CA  1 
ATOM   2181  C  C   . PHE A 1 320 ? 152.251 98.931  175.440 1.00 69.15  ?  309 PHE A C   1 
ATOM   2182  O  O   . PHE A 1 320 ? 153.050 99.741  175.862 1.00 69.15  ?  309 PHE A O   1 
ATOM   2183  C  CB  . PHE A 1 320 ? 152.681 98.138  173.145 1.00 69.15  ?  309 PHE A CB  1 
ATOM   2184  C  CG  . PHE A 1 320 ? 153.748 97.510  172.306 1.00 69.15  ?  309 PHE A CG  1 
ATOM   2185  C  CD1 . PHE A 1 320 ? 154.485 96.449  172.772 1.00 69.15  ?  309 PHE A CD1 1 
ATOM   2186  C  CD2 . PHE A 1 320 ? 153.989 97.973  171.035 1.00 69.15  ?  309 PHE A CD2 1 
ATOM   2187  C  CE1 . PHE A 1 320 ? 155.459 95.872  171.992 1.00 69.15  ?  309 PHE A CE1 1 
ATOM   2188  C  CE2 . PHE A 1 320 ? 154.956 97.398  170.245 1.00 69.15  ?  309 PHE A CE2 1 
ATOM   2189  C  CZ  . PHE A 1 320 ? 155.692 96.342  170.724 1.00 69.15  ?  309 PHE A CZ  1 
ATOM   2190  N  N   . LYS A 1 321 ? 150.955 99.048  175.664 1.00 71.26  ?  310 LYS A N   1 
ATOM   2191  C  CA  . LYS A 1 321 ? 150.457 100.171 176.425 1.00 71.26  ?  310 LYS A CA  1 
ATOM   2192  C  C   . LYS A 1 321 ? 151.047 100.194 177.823 1.00 71.26  ?  310 LYS A C   1 
ATOM   2193  O  O   . LYS A 1 321 ? 151.415 101.241 178.311 1.00 71.26  ?  310 LYS A O   1 
ATOM   2194  C  CB  . LYS A 1 321 ? 148.944 100.043 176.549 1.00 71.26  ?  310 LYS A CB  1 
ATOM   2195  C  CG  . LYS A 1 321 ? 148.239 101.303 177.004 1.00 71.26  ?  310 LYS A CG  1 
ATOM   2196  C  CD  . LYS A 1 321 ? 146.971 100.964 177.761 1.00 71.26  ?  310 LYS A CD  1 
ATOM   2197  C  CE  . LYS A 1 321 ? 146.378 99.662  177.258 1.00 71.26  ?  310 LYS A CE  1 
ATOM   2198  N  NZ  . LYS A 1 321 ? 145.378 99.121  178.212 1.00 71.26  1  310 LYS A NZ  1 
ATOM   2199  N  N   . ASN A 1 322 ? 151.061 99.063  178.513 1.00 73.06  ?  311 ASN A N   1 
ATOM   2200  C  CA  . ASN A 1 322 ? 151.679 99.006  179.834 1.00 73.06  ?  311 ASN A CA  1 
ATOM   2201  C  C   . ASN A 1 322 ? 153.201 99.030  179.854 1.00 73.06  ?  311 ASN A C   1 
ATOM   2202  O  O   . ASN A 1 322 ? 153.814 99.717  180.654 1.00 73.06  ?  311 ASN A O   1 
ATOM   2203  C  CB  . ASN A 1 322 ? 151.152 97.818  180.623 1.00 73.06  ?  311 ASN A CB  1 
ATOM   2204  C  CG  . ASN A 1 322 ? 149.665 97.899  180.846 1.00 73.06  ?  311 ASN A CG  1 
ATOM   2205  O  OD1 . ASN A 1 322 ? 148.997 96.888  181.003 1.00 73.06  ?  311 ASN A OD1 1 
ATOM   2206  N  ND2 . ASN A 1 322 ? 149.137 99.112  180.849 1.00 73.06  ?  311 ASN A ND2 1 
ATOM   2207  N  N   . ARG A 1 323 ? 153.793 98.240  178.970 1.00 73.67  ?  312 ARG A N   1 
ATOM   2208  C  CA  . ARG A 1 323 ? 155.236 98.109  178.867 1.00 73.67  ?  312 ARG A CA  1 
ATOM   2209  C  C   . ARG A 1 323 ? 156.039 99.322  178.389 1.00 73.67  ?  312 ARG A C   1 
ATOM   2210  O  O   . ARG A 1 323 ? 157.060 99.656  178.971 1.00 73.67  ?  312 ARG A O   1 
ATOM   2211  C  CB  . ARG A 1 323 ? 155.542 96.906  177.985 1.00 73.67  ?  312 ARG A CB  1 
ATOM   2212  C  CG  . ARG A 1 323 ? 157.009 96.676  177.707 1.00 73.67  ?  312 ARG A CG  1 
ATOM   2213  C  CD  . ARG A 1 323 ? 157.206 95.300  177.115 1.00 73.67  ?  312 ARG A CD  1 
ATOM   2214  N  NE  . ARG A 1 323 ? 156.636 94.296  178.003 1.00 73.67  ?  312 ARG A NE  1 
ATOM   2215  C  CZ  . ARG A 1 323 ? 156.494 93.012  177.698 1.00 73.67  ?  312 ARG A CZ  1 
ATOM   2216  N  NH1 . ARG A 1 323 ? 155.962 92.185  178.583 1.00 73.67  1  312 ARG A NH1 1 
ATOM   2217  N  NH2 . ARG A 1 323 ? 156.879 92.554  176.515 1.00 73.67  ?  312 ARG A NH2 1 
ATOM   2218  N  N   . PHE A 1 324 ? 155.571 99.983  177.338 1.00 70.31  ?  313 PHE A N   1 
ATOM   2219  C  CA  . PHE A 1 324 ? 156.279 101.129 176.782 1.00 70.31  ?  313 PHE A CA  1 
ATOM   2220  C  C   . PHE A 1 324 ? 155.541 102.439 176.891 1.00 70.31  ?  313 PHE A C   1 
ATOM   2221  O  O   . PHE A 1 324 ? 155.983 103.429 176.335 1.00 70.31  ?  313 PHE A O   1 
ATOM   2222  C  CB  . PHE A 1 324 ? 156.610 100.883 175.314 1.00 70.31  ?  313 PHE A CB  1 
ATOM   2223  C  CG  . PHE A 1 324 ? 157.546 99.745  175.092 1.00 70.31  ?  313 PHE A CG  1 
ATOM   2224  C  CD1 . PHE A 1 324 ? 158.732 99.669  175.786 1.00 70.31  ?  313 PHE A CD1 1 
ATOM   2225  C  CD2 . PHE A 1 324 ? 157.249 98.764  174.176 1.00 70.31  ?  313 PHE A CD2 1 
ATOM   2226  C  CE1 . PHE A 1 324 ? 159.601 98.627  175.578 1.00 70.31  ?  313 PHE A CE1 1 
ATOM   2227  C  CE2 . PHE A 1 324 ? 158.112 97.715  173.961 1.00 70.31  ?  313 PHE A CE2 1 
ATOM   2228  C  CZ  . PHE A 1 324 ? 159.292 97.649  174.659 1.00 70.31  ?  313 PHE A CZ  1 
ATOM   2229  N  N   . LYS A 1 325 ? 154.395 102.417 177.558 1.00 69.43  ?  314 LYS A N   1 
ATOM   2230  C  CA  . LYS A 1 325 ? 153.535 103.589 177.759 1.00 69.43  ?  314 LYS A CA  1 
ATOM   2231  C  C   . LYS A 1 325 ? 153.066 104.249 176.464 1.00 69.43  ?  314 LYS A C   1 
ATOM   2232  O  O   . LYS A 1 325 ? 152.925 105.462 176.398 1.00 69.43  ?  314 LYS A O   1 
ATOM   2233  C  CB  . LYS A 1 325 ? 154.172 104.617 178.701 1.00 69.43  ?  314 LYS A CB  1 
ATOM   2234  C  CG  . LYS A 1 325 ? 154.424 104.097 180.099 1.00 69.43  ?  314 LYS A CG  1 
ATOM   2235  C  CD  . LYS A 1 325 ? 155.723 103.323 180.167 1.00 69.43  ?  314 LYS A CD  1 
ATOM   2236  C  CE  . LYS A 1 325 ? 155.709 102.342 181.322 1.00 69.43  ?  314 LYS A CE  1 
ATOM   2237  N  NZ  . LYS A 1 325 ? 156.821 101.360 181.211 1.00 69.43  1  314 LYS A NZ  1 
ATOM   2238  N  N   . VAL A 1 326 ? 152.816 103.443 175.444 1.00 64.96  ?  315 VAL A N   1 
ATOM   2239  C  CA  . VAL A 1 326 ? 152.377 103.954 174.158 1.00 64.96  ?  315 VAL A CA  1 
ATOM   2240  C  C   . VAL A 1 326 ? 150.920 104.369 174.150 1.00 64.96  ?  315 VAL A C   1 
ATOM   2241  O  O   . VAL A 1 326 ? 150.104 103.773 174.832 1.00 64.96  ?  315 VAL A O   1 
ATOM   2242  C  CB  . VAL A 1 326 ? 152.639 102.937 173.040 1.00 64.96  ?  315 VAL A CB  1 
ATOM   2243  C  CG1 . VAL A 1 326 ? 154.093 102.506 173.058 1.00 64.96  ?  315 VAL A CG1 1 
ATOM   2244  C  CG2 . VAL A 1 326 ? 151.719 101.739 173.167 1.00 64.96  ?  315 VAL A CG2 1 
ATOM   2245  N  N   . ALA A 1 327 ? 150.601 105.422 173.411 1.00 61.54  ?  316 ALA A N   1 
ATOM   2246  C  CA  . ALA A 1 327 ? 149.223 105.859 173.288 1.00 61.54  ?  316 ALA A CA  1 
ATOM   2247  C  C   . ALA A 1 327 ? 148.516 104.869 172.371 1.00 61.54  ?  316 ALA A C   1 
ATOM   2248  O  O   . ALA A 1 327 ? 149.051 104.475 171.354 1.00 61.54  ?  316 ALA A O   1 
ATOM   2249  C  CB  . ALA A 1 327 ? 149.157 107.257 172.722 1.00 61.54  ?  316 ALA A CB  1 
ATOM   2250  N  N   . VAL A 1 328 ? 147.304 104.486 172.718 1.00 60.33  ?  317 VAL A N   1 
ATOM   2251  C  CA  . VAL A 1 328 ? 146.549 103.526 171.938 1.00 60.33  ?  317 VAL A CA  1 
ATOM   2252  C  C   . VAL A 1 328 ? 145.179 104.094 171.665 1.00 60.33  ?  317 VAL A C   1 
ATOM   2253  O  O   . VAL A 1 328 ? 144.763 105.047 172.309 1.00 60.33  ?  317 VAL A O   1 
ATOM   2254  C  CB  . VAL A 1 328 ? 146.409 102.180 172.664 1.00 60.33  ?  317 VAL A CB  1 
ATOM   2255  C  CG1 . VAL A 1 328 ? 147.693 101.388 172.570 1.00 60.33  ?  317 VAL A CG1 1 
ATOM   2256  C  CG2 . VAL A 1 328 ? 146.006 102.384 174.105 1.00 60.33  ?  317 VAL A CG2 1 
ATOM   2257  N  N   . VAL A 1 329 ? 144.460 103.507 170.714 1.00 59.46  ?  318 VAL A N   1 
ATOM   2258  C  CA  . VAL A 1 329 ? 143.120 103.983 170.383 1.00 59.46  ?  318 VAL A CA  1 
ATOM   2259  C  C   . VAL A 1 329 ? 142.220 103.873 171.609 1.00 59.46  ?  318 VAL A C   1 
ATOM   2260  O  O   . VAL A 1 329 ? 141.460 104.781 171.896 1.00 59.46  ?  318 VAL A O   1 
ATOM   2261  C  CB  . VAL A 1 329 ? 142.531 103.215 169.185 1.00 59.46  ?  318 VAL A CB  1 
ATOM   2262  C  CG1 . VAL A 1 329 ? 141.035 103.441 169.070 1.00 59.46  ?  318 VAL A CG1 1 
ATOM   2263  C  CG2 . VAL A 1 329 ? 143.233 103.628 167.905 1.00 59.46  ?  318 VAL A CG2 1 
ATOM   2264  N  N   . GLY A 1 330 ? 142.315 102.768 172.337 1.00 63.18  ?  319 GLY A N   1 
ATOM   2265  C  CA  . GLY A 1 330 ? 141.574 102.599 173.561 1.00 63.18  ?  319 GLY A CA  1 
ATOM   2266  C  C   . GLY A 1 330 ? 140.160 102.132 173.409 1.00 63.18  ?  319 GLY A C   1 
ATOM   2267  O  O   . GLY A 1 330 ? 139.677 101.900 172.312 1.00 63.18  ?  319 GLY A O   1 
ATOM   2268  N  N   . ASP A 1 331 ? 139.487 101.994 174.538 1.00 67.63  ?  320 ASP A N   1 
ATOM   2269  C  CA  . ASP A 1 331 ? 138.117 101.547 174.546 1.00 67.63  ?  320 ASP A CA  1 
ATOM   2270  C  C   . ASP A 1 331 ? 137.185 102.608 174.013 1.00 67.63  ?  320 ASP A C   1 
ATOM   2271  O  O   . ASP A 1 331 ? 137.253 103.764 174.397 1.00 67.63  ?  320 ASP A O   1 
ATOM   2272  C  CB  . ASP A 1 331 ? 137.707 101.155 175.958 1.00 67.63  ?  320 ASP A CB  1 
ATOM   2273  C  CG  . ASP A 1 331 ? 137.980 99.706  176.255 1.00 67.63  ?  320 ASP A CG  1 
ATOM   2274  O  OD1 . ASP A 1 331 ? 138.023 98.903  175.304 1.00 67.63  ?  320 ASP A OD1 1 
ATOM   2275  O  OD2 . ASP A 1 331 ? 138.138 99.360  177.440 1.00 67.63  -1 320 ASP A OD2 1 
ATOM   2276  N  N   . MET A 1 332 ? 136.301 102.184 173.125 1.00 65.81  ?  321 MET A N   1 
ATOM   2277  C  CA  . MET A 1 332 ? 135.306 103.048 172.529 1.00 65.81  ?  321 MET A CA  1 
ATOM   2278  C  C   . MET A 1 332 ? 134.008 102.455 172.987 1.00 65.81  ?  321 MET A C   1 
ATOM   2279  O  O   . MET A 1 332 ? 133.848 101.245 172.952 1.00 65.81  ?  321 MET A O   1 
ATOM   2280  C  CB  . MET A 1 332 ? 135.361 102.988 171.005 1.00 65.81  ?  321 MET A CB  1 
ATOM   2281  C  CG  . MET A 1 332 ? 136.649 103.492 170.396 1.00 65.81  ?  321 MET A CG  1 
ATOM   2282  S  SD  . MET A 1 332 ? 136.637 103.571 168.598 1.00 65.81  ?  321 MET A SD  1 
ATOM   2283  C  CE  . MET A 1 332 ? 137.013 101.889 168.138 1.00 65.81  ?  321 MET A CE  1 
ATOM   2284  N  N   . ASN A 1 333 ? 133.088 103.271 173.469 1.00 67.45  ?  322 ASN A N   1 
ATOM   2285  C  CA  . ASN A 1 333 ? 131.820 102.705 173.873 1.00 67.45  ?  322 ASN A CA  1 
ATOM   2286  C  C   . ASN A 1 333 ? 131.075 102.380 172.600 1.00 67.45  ?  322 ASN A C   1 
ATOM   2287  O  O   . ASN A 1 333 ? 131.062 103.182 171.671 1.00 67.45  ?  322 ASN A O   1 
ATOM   2288  C  CB  . ASN A 1 333 ? 131.026 103.652 174.775 1.00 67.45  ?  322 ASN A CB  1 
ATOM   2289  C  CG  . ASN A 1 333 ? 130.893 105.048 174.198 1.00 67.45  ?  322 ASN A CG  1 
ATOM   2290  O  OD1 . ASN A 1 333 ? 130.457 105.233 173.061 1.00 67.45  ?  322 ASN A OD1 1 
ATOM   2291  N  ND2 . ASN A 1 333 ? 131.254 106.045 174.997 1.00 67.45  ?  322 ASN A ND2 1 
ATOM   2292  N  N   . PRO A 1 334 ? 130.495 101.178 172.530 1.00 61.99  ?  323 PRO A N   1 
ATOM   2293  C  CA  . PRO A 1 334 ? 129.759 100.784 171.333 1.00 61.99  ?  323 PRO A CA  1 
ATOM   2294  C  C   . PRO A 1 334 ? 128.450 101.530 171.218 1.00 61.99  ?  323 PRO A C   1 
ATOM   2295  O  O   . PRO A 1 334 ? 127.906 101.969 172.210 1.00 61.99  ?  323 PRO A O   1 
ATOM   2296  C  CB  . PRO A 1 334 ? 129.507 99.296  171.554 1.00 61.99  ?  323 PRO A CB  1 
ATOM   2297  C  CG  . PRO A 1 334 ? 129.564 99.113  173.019 1.00 61.99  ?  323 PRO A CG  1 
ATOM   2298  C  CD  . PRO A 1 334 ? 130.578 100.090 173.513 1.00 61.99  ?  323 PRO A CD  1 
ATOM   2299  N  N   . GLY A 1 335 ? 127.952 101.674 170.007 1.00 55.16  ?  324 GLY A N   1 
ATOM   2300  C  CA  . GLY A 1 335 ? 126.704 102.358 169.778 1.00 55.16  ?  324 GLY A CA  1 
ATOM   2301  C  C   . GLY A 1 335 ? 126.871 103.813 169.457 1.00 55.16  ?  324 GLY A C   1 
ATOM   2302  O  O   . GLY A 1 335 ? 127.913 104.387 169.671 1.00 55.16  ?  324 GLY A O   1 
ATOM   2303  N  N   . PHE A 1 336 ? 125.833 104.388 168.881 1.00 53.77  ?  325 PHE A N   1 
ATOM   2304  C  CA  . PHE A 1 336 ? 125.814 105.786 168.521 1.00 53.77  ?  325 PHE A CA  1 
ATOM   2305  C  C   . PHE A 1 336 ? 125.434 106.674 169.689 1.00 53.77  ?  325 PHE A C   1 
ATOM   2306  O  O   . PHE A 1 336 ? 124.889 106.213 170.679 1.00 53.77  ?  325 PHE A O   1 
ATOM   2307  C  CB  . PHE A 1 336 ? 124.848 106.009 167.368 1.00 53.77  ?  325 PHE A CB  1 
ATOM   2308  C  CG  . PHE A 1 336 ? 125.218 105.273 166.119 1.00 53.77  ?  325 PHE A CG  1 
ATOM   2309  C  CD1 . PHE A 1 336 ? 126.003 105.872 165.161 1.00 53.77  ?  325 PHE A CD1 1 
ATOM   2310  C  CD2 . PHE A 1 336 ? 124.777 103.988 165.907 1.00 53.77  ?  325 PHE A CD2 1 
ATOM   2311  C  CE1 . PHE A 1 336 ? 126.343 105.206 164.009 1.00 53.77  ?  325 PHE A CE1 1 
ATOM   2312  C  CE2 . PHE A 1 336 ? 125.106 103.316 164.757 1.00 53.77  ?  325 PHE A CE2 1 
ATOM   2313  C  CZ  . PHE A 1 336 ? 125.891 103.927 163.804 1.00 53.77  ?  325 PHE A CZ  1 
ATOM   2314  N  N   . GLN A 1 337 ? 125.751 107.953 169.575 1.00 56.94  ?  326 GLN A N   1 
ATOM   2315  C  CA  . GLN A 1 337 ? 125.401 108.922 170.590 1.00 56.94  ?  326 GLN A CA  1 
ATOM   2316  C  C   . GLN A 1 337 ? 123.988 109.406 170.308 1.00 56.94  ?  326 GLN A C   1 
ATOM   2317  O  O   . GLN A 1 337 ? 123.487 109.248 169.204 1.00 56.94  ?  326 GLN A O   1 
ATOM   2318  C  CB  . GLN A 1 337 ? 126.326 110.129 170.495 1.00 56.94  ?  326 GLN A CB  1 
ATOM   2319  C  CG  . GLN A 1 337 ? 127.797 109.833 170.627 1.00 56.94  ?  326 GLN A CG  1 
ATOM   2320  C  CD  . GLN A 1 337 ? 128.188 109.533 172.045 1.00 56.94  ?  326 GLN A CD  1 
ATOM   2321  O  OE1 . GLN A 1 337 ? 129.183 108.868 172.295 1.00 56.94  ?  326 GLN A OE1 1 
ATOM   2322  N  NE2 . GLN A 1 337 ? 127.404 110.021 172.985 1.00 56.94  ?  326 GLN A NE2 1 
ATOM   2323  N  N   . PRO A 1 338 ? 123.325 109.992 171.308 1.00 58.39  ?  327 PRO A N   1 
ATOM   2324  C  CA  . PRO A 1 338 ? 121.993 110.536 171.046 1.00 58.39  ?  327 PRO A CA  1 
ATOM   2325  C  C   . PRO A 1 338 ? 122.130 111.873 170.329 1.00 58.39  ?  327 PRO A C   1 
ATOM   2326  O  O   . PRO A 1 338 ? 123.164 112.511 170.441 1.00 58.39  ?  327 PRO A O   1 
ATOM   2327  C  CB  . PRO A 1 338 ? 121.424 110.758 172.446 1.00 58.39  ?  327 PRO A CB  1 
ATOM   2328  C  CG  . PRO A 1 338 ? 122.242 109.901 173.344 1.00 58.39  ?  327 PRO A CG  1 
ATOM   2329  C  CD  . PRO A 1 338 ? 123.608 109.889 172.745 1.00 58.39  ?  327 PRO A CD  1 
ATOM   2330  N  N   . PRO A 1 339 ? 121.093 112.303 169.606 1.00 57.64  ?  328 PRO A N   1 
ATOM   2331  C  CA  . PRO A 1 339 ? 121.137 113.575 168.884 1.00 57.64  ?  328 PRO A CA  1 
ATOM   2332  C  C   . PRO A 1 339 ? 121.501 114.736 169.796 1.00 57.64  ?  328 PRO A C   1 
ATOM   2333  O  O   . PRO A 1 339 ? 121.019 114.834 170.913 1.00 57.64  ?  328 PRO A O   1 
ATOM   2334  C  CB  . PRO A 1 339 ? 119.715 113.739 168.376 1.00 57.64  ?  328 PRO A CB  1 
ATOM   2335  C  CG  . PRO A 1 339 ? 119.172 112.362 168.306 1.00 57.64  ?  328 PRO A CG  1 
ATOM   2336  C  CD  . PRO A 1 339 ? 119.834 111.580 169.392 1.00 57.64  ?  328 PRO A CD  1 
ATOM   2337  N  N   . ILE A 1 340 ? 122.337 115.628 169.295 1.00 59.47  ?  329 ILE A N   1 
ATOM   2338  C  CA  . ILE A 1 340 ? 122.796 116.777 170.046 1.00 59.47  ?  329 ILE A CA  1 
ATOM   2339  C  C   . ILE A 1 340 ? 122.265 118.031 169.385 1.00 59.47  ?  329 ILE A C   1 
ATOM   2340  O  O   . ILE A 1 340 ? 122.205 118.115 168.172 1.00 59.47  ?  329 ILE A O   1 
ATOM   2341  C  CB  . ILE A 1 340 ? 124.335 116.832 170.066 1.00 59.47  ?  329 ILE A CB  1 
ATOM   2342  C  CG1 . ILE A 1 340 ? 124.847 117.522 171.321 1.00 59.47  ?  329 ILE A CG1 1 
ATOM   2343  C  CG2 . ILE A 1 340 ? 124.872 117.527 168.828 1.00 59.47  ?  329 ILE A CG2 1 
ATOM   2344  C  CD1 . ILE A 1 340 ? 126.355 117.531 171.420 1.00 59.47  ?  329 ILE A CD1 1 
ATOM   2345  N  N   . THR A 1 341 ? 121.836 118.993 170.182 1.00 63.31  ?  330 THR A N   1 
ATOM   2346  C  CA  . THR A 1 341 ? 121.330 120.238 169.632 1.00 63.31  ?  330 THR A CA  1 
ATOM   2347  C  C   . THR A 1 341 ? 122.495 121.147 169.319 1.00 63.31  ?  330 THR A C   1 
ATOM   2348  O  O   . THR A 1 341 ? 123.360 121.347 170.150 1.00 63.31  ?  330 THR A O   1 
ATOM   2349  C  CB  . THR A 1 341 ? 120.392 120.960 170.614 1.00 63.31  ?  330 THR A CB  1 
ATOM   2350  O  OG1 . THR A 1 341 ? 119.182 120.214 170.752 1.00 63.31  ?  330 THR A OG1 1 
ATOM   2351  C  CG2 . THR A 1 341 ? 120.054 122.334 170.107 1.00 63.31  ?  330 THR A CG2 1 
ATOM   2352  N  N   . PRO A 1 342 ? 122.529 121.694 168.104 1.00 63.75  ?  331 PRO A N   1 
ATOM   2353  C  CA  . PRO A 1 342 ? 123.596 122.610 167.688 1.00 63.75  ?  331 PRO A CA  1 
ATOM   2354  C  C   . PRO A 1 342 ? 123.650 123.832 168.593 1.00 63.75  ?  331 PRO A C   1 
ATOM   2355  O  O   . PRO A 1 342 ? 122.610 124.340 168.978 1.00 63.75  ?  331 PRO A O   1 
ATOM   2356  C  CB  . PRO A 1 342 ? 123.160 123.035 166.288 1.00 63.75  ?  331 PRO A CB  1 
ATOM   2357  C  CG  . PRO A 1 342 ? 122.286 121.940 165.805 1.00 63.75  ?  331 PRO A CG  1 
ATOM   2358  C  CD  . PRO A 1 342 ? 121.626 121.340 167.000 1.00 63.75  ?  331 PRO A CD  1 
ATOM   2359  N  N   . ASP A 1 343 ? 124.836 124.327 168.910 1.00 66.86  ?  332 ASP A N   1 
ATOM   2360  C  CA  . ASP A 1 343 ? 124.923 125.491 169.769 1.00 66.86  ?  332 ASP A CA  1 
ATOM   2361  C  C   . ASP A 1 343 ? 124.989 126.749 168.947 1.00 66.86  ?  332 ASP A C   1 
ATOM   2362  O  O   . ASP A 1 343 ? 125.884 126.922 168.144 1.00 66.86  ?  332 ASP A O   1 
ATOM   2363  C  CB  . ASP A 1 343 ? 126.178 125.450 170.624 1.00 66.86  ?  332 ASP A CB  1 
ATOM   2364  C  CG  . ASP A 1 343 ? 126.168 124.336 171.626 1.00 66.86  ?  332 ASP A CG  1 
ATOM   2365  O  OD1 . ASP A 1 343 ? 126.923 124.430 172.615 1.00 66.86  ?  332 ASP A OD1 1 
ATOM   2366  O  OD2 . ASP A 1 343 ? 125.424 123.361 171.434 1.00 66.86  -1 332 ASP A OD2 1 
ATOM   2367  N  N   . VAL A 1 344 ? 124.050 127.648 169.190 1.00 66.63  ?  333 VAL A N   1 
ATOM   2368  C  CA  . VAL A 1 344 ? 123.999 128.926 168.502 1.00 66.63  ?  333 VAL A CA  1 
ATOM   2369  C  C   . VAL A 1 344 ? 125.225 129.783 168.815 1.00 66.63  ?  333 VAL A C   1 
ATOM   2370  O  O   . VAL A 1 344 ? 125.699 130.519 167.965 1.00 66.63  ?  333 VAL A O   1 
ATOM   2371  C  CB  . VAL A 1 344 ? 122.687 129.674 168.775 1.00 66.63  ?  333 VAL A CB  1 
ATOM   2372  C  CG1 . VAL A 1 344 ? 121.790 129.600 167.557 1.00 66.63  ?  333 VAL A CG1 1 
ATOM   2373  C  CG2 . VAL A 1 344 ? 121.990 129.089 169.989 1.00 66.63  ?  333 VAL A CG2 1 
ATOM   2374  N  N   . GLU A 1 345 ? 125.725 129.714 170.043 1.00 68.63  ?  334 GLU A N   1 
ATOM   2375  C  CA  . GLU A 1 345 ? 126.908 130.487 170.398 1.00 68.63  ?  334 GLU A CA  1 
ATOM   2376  C  C   . GLU A 1 345 ? 128.106 130.056 169.558 1.00 68.63  ?  334 GLU A C   1 
ATOM   2377  O  O   . GLU A 1 345 ? 128.870 130.887 169.098 1.00 68.63  ?  334 GLU A O   1 
ATOM   2378  C  CB  . GLU A 1 345 ? 127.237 130.357 171.880 1.00 68.63  ?  334 GLU A CB  1 
ATOM   2379  C  CG  . GLU A 1 345 ? 128.255 131.379 172.344 1.00 68.63  ?  334 GLU A CG  1 
ATOM   2380  C  CD  . GLU A 1 345 ? 129.070 130.895 173.515 1.00 68.63  ?  334 GLU A CD  1 
ATOM   2381  O  OE1 . GLU A 1 345 ? 129.147 129.664 173.707 1.00 68.63  ?  334 GLU A OE1 1 
ATOM   2382  O  OE2 . GLU A 1 345 ? 129.636 131.740 174.237 1.00 68.63  -1 334 GLU A OE2 1 
ATOM   2383  N  N   . THR A 1 346 ? 128.252 128.750 169.352 1.00 64.55  ?  335 THR A N   1 
ATOM   2384  C  CA  . THR A 1 346 ? 129.314 128.196 168.522 1.00 64.55  ?  335 THR A CA  1 
ATOM   2385  C  C   . THR A 1 346 ? 129.157 128.659 167.081 1.00 64.55  ?  335 THR A C   1 
ATOM   2386  O  O   . THR A 1 346 ? 130.143 128.919 166.417 1.00 64.55  ?  335 THR A O   1 
ATOM   2387  C  CB  . THR A 1 346 ? 129.351 126.663 168.581 1.00 64.55  ?  335 THR A CB  1 
ATOM   2388  O  OG1 . THR A 1 346 ? 129.576 126.254 169.926 1.00 64.55  ?  335 THR A OG1 1 
ATOM   2389  C  CG2 . THR A 1 346 ? 130.463 126.109 167.706 1.00 64.55  ?  335 THR A CG2 1 
ATOM   2390  N  N   . PHE A 1 347 ? 127.920 128.746 166.598 1.00 62.83  ?  336 PHE A N   1 
ATOM   2391  C  CA  . PHE A 1 347 ? 127.664 129.201 165.242 1.00 62.83  ?  336 PHE A CA  1 
ATOM   2392  C  C   . PHE A 1 347 ? 128.169 130.610 165.031 1.00 62.83  ?  336 PHE A C   1 
ATOM   2393  O  O   . PHE A 1 347 ? 128.765 130.893 164.007 1.00 62.83  ?  336 PHE A O   1 
ATOM   2394  C  CB  . PHE A 1 347 ? 126.165 129.226 164.965 1.00 62.83  ?  336 PHE A CB  1 
ATOM   2395  C  CG  . PHE A 1 347 ? 125.595 127.903 164.587 1.00 62.83  ?  336 PHE A CG  1 
ATOM   2396  C  CD1 . PHE A 1 347 ? 126.231 126.741 164.949 1.00 62.83  ?  336 PHE A CD1 1 
ATOM   2397  C  CD2 . PHE A 1 347 ? 124.406 127.824 163.902 1.00 62.83  ?  336 PHE A CD2 1 
ATOM   2398  C  CE1 . PHE A 1 347 ? 125.707 125.519 164.615 1.00 62.83  ?  336 PHE A CE1 1 
ATOM   2399  C  CE2 . PHE A 1 347 ? 123.871 126.599 163.565 1.00 62.83  ?  336 PHE A CE2 1 
ATOM   2400  C  CZ  . PHE A 1 347 ? 124.529 125.445 163.922 1.00 62.83  ?  336 PHE A CZ  1 
ATOM   2401  N  N   . GLN A 1 348 ? 127.927 131.495 165.994 1.00 67.15  ?  337 GLN A N   1 
ATOM   2402  C  CA  . GLN A 1 348 ? 128.377 132.879 165.886 1.00 67.15  ?  337 GLN A CA  1 
ATOM   2403  C  C   . GLN A 1 348 ? 129.879 132.983 165.856 1.00 67.15  ?  337 GLN A C   1 
ATOM   2404  O  O   . GLN A 1 348 ? 130.446 133.721 165.066 1.00 67.15  ?  337 GLN A O   1 
ATOM   2405  C  CB  . GLN A 1 348 ? 127.894 133.686 167.082 1.00 67.15  ?  337 GLN A CB  1 
ATOM   2406  C  CG  . GLN A 1 348 ? 126.410 133.600 167.361 1.00 67.15  ?  337 GLN A CG  1 
ATOM   2407  C  CD  . GLN A 1 348 ? 126.086 134.015 168.776 1.00 67.15  ?  337 GLN A CD  1 
ATOM   2408  O  OE1 . GLN A 1 348 ? 124.933 133.975 169.200 1.00 67.15  ?  337 GLN A OE1 1 
ATOM   2409  N  NE2 . GLN A 1 348 ? 127.109 134.404 169.521 1.00 67.15  ?  337 GLN A NE2 1 
ATOM   2410  N  N   . ASN A 1 349 ? 130.518 132.230 166.737 1.00 66.47  ?  338 ASN A N   1 
ATOM   2411  C  CA  . ASN A 1 349 ? 131.965 132.216 166.849 1.00 66.47  ?  338 ASN A CA  1 
ATOM   2412  C  C   . ASN A 1 349 ? 132.705 131.672 165.631 1.00 66.47  ?  338 ASN A C   1 
ATOM   2413  O  O   . ASN A 1 349 ? 133.745 132.186 165.251 1.00 66.47  ?  338 ASN A O   1 
ATOM   2414  C  CB  . ASN A 1 349 ? 132.386 131.467 168.113 1.00 66.47  ?  338 ASN A CB  1 
ATOM   2415  C  CG  . ASN A 1 349 ? 131.981 132.195 169.383 1.00 66.47  ?  338 ASN A CG  1 
ATOM   2416  O  OD1 . ASN A 1 349 ? 131.968 133.418 169.423 1.00 66.47  ?  338 ASN A OD1 1 
ATOM   2417  N  ND2 . ASN A 1 349 ? 131.651 131.442 170.425 1.00 66.47  ?  338 ASN A ND2 1 
ATOM   2418  N  N   . THR A 1 350 ? 132.159 130.627 165.028 1.00 61.81  ?  339 THR A N   1 
ATOM   2419  C  CA  . THR A 1 350 ? 132.782 129.963 163.890 1.00 61.81  ?  339 THR A CA  1 
ATOM   2420  C  C   . THR A 1 350 ? 132.210 130.169 162.496 1.00 61.81  ?  339 THR A C   1 
ATOM   2421  O  O   . THR A 1 350 ? 132.599 129.457 161.607 1.00 61.81  ?  339 THR A O   1 
ATOM   2422  C  CB  . THR A 1 350 ? 132.818 128.442 164.112 1.00 61.81  ?  339 THR A CB  1 
ATOM   2423  O  OG1 . THR A 1 350 ? 131.483 127.956 164.268 1.00 61.81  ?  339 THR A OG1 1 
ATOM   2424  C  CG2 . THR A 1 350 ? 133.615 128.099 165.343 1.00 61.81  ?  339 THR A CG2 1 
ATOM   2425  N  N   . VAL A 1 351 ? 131.353 131.149 162.261 1.00 60.10  ?  340 VAL A N   1 
ATOM   2426  C  CA  . VAL A 1 351 ? 130.742 131.263 160.934 1.00 60.10  ?  340 VAL A CA  1 
ATOM   2427  C  C   . VAL A 1 351 ? 131.725 131.432 159.766 1.00 60.10  ?  340 VAL A C   1 
ATOM   2428  O  O   . VAL A 1 351 ? 131.525 130.847 158.711 1.00 60.10  ?  340 VAL A O   1 
ATOM   2429  C  CB  . VAL A 1 351 ? 129.639 132.341 160.904 1.00 60.10  ?  340 VAL A CB  1 
ATOM   2430  C  CG1 . VAL A 1 351 ? 130.158 133.657 161.437 1.00 60.10  ?  340 VAL A CG1 1 
ATOM   2431  C  CG2 . VAL A 1 351 ? 129.066 132.500 159.508 1.00 60.10  ?  340 VAL A CG2 1 
ATOM   2432  N  N   . GLY A 1 352 ? 132.774 132.222 159.942 1.00 57.65  ?  341 GLY A N   1 
ATOM   2433  C  CA  . GLY A 1 352 ? 133.775 132.389 158.906 1.00 57.65  ?  341 GLY A CA  1 
ATOM   2434  C  C   . GLY A 1 352 ? 134.511 131.095 158.606 1.00 57.65  ?  341 GLY A C   1 
ATOM   2435  O  O   . GLY A 1 352 ? 134.836 130.807 157.464 1.00 57.65  ?  341 GLY A O   1 
ATOM   2436  N  N   . ASP A 1 353 ? 134.815 130.333 159.653 1.00 58.69  ?  342 ASP A N   1 
ATOM   2437  C  CA  . ASP A 1 353 ? 135.499 129.055 159.526 1.00 58.69  ?  342 ASP A CA  1 
ATOM   2438  C  C   . ASP A 1 353 ? 134.659 128.071 158.748 1.00 58.69  ?  342 ASP A C   1 
ATOM   2439  O  O   . ASP A 1 353 ? 135.163 127.321 157.935 1.00 58.69  ?  342 ASP A O   1 
ATOM   2440  C  CB  . ASP A 1 353 ? 135.731 128.440 160.899 1.00 58.69  ?  342 ASP A CB  1 
ATOM   2441  C  CG  . ASP A 1 353 ? 136.735 129.188 161.711 1.00 58.69  ?  342 ASP A CG  1 
ATOM   2442  O  OD1 . ASP A 1 353 ? 136.479 129.392 162.910 1.00 58.69  ?  342 ASP A OD1 1 
ATOM   2443  O  OD2 . ASP A 1 353 ? 137.782 129.567 161.163 1.00 58.69  -1 342 ASP A OD2 1 
ATOM   2444  N  N   . CYS A 1 354 ? 133.368 128.077 159.037 1.00 55.64  ?  343 CYS A N   1 
ATOM   2445  C  CA  . CYS A 1 354 ? 132.408 127.199 158.403 1.00 55.64  ?  343 CYS A CA  1 
ATOM   2446  C  C   . CYS A 1 354 ? 132.275 127.434 156.925 1.00 55.64  ?  343 CYS A C   1 
ATOM   2447  O  O   . CYS A 1 354 ? 132.080 126.495 156.185 1.00 55.64  ?  343 CYS A O   1 
ATOM   2448  C  CB  . CYS A 1 354 ? 131.067 127.279 159.100 1.00 55.64  ?  343 CYS A CB  1 
ATOM   2449  S  SG  . CYS A 1 354 ? 131.184 126.592 160.742 1.00 55.64  ?  343 CYS A SG  1 
ATOM   2450  N  N   . PHE A 1 355 ? 132.332 128.686 156.492 1.00 53.25  ?  344 PHE A N   1 
ATOM   2451  C  CA  . PHE A 1 355 ? 132.272 128.967 155.070 1.00 53.25  ?  344 PHE A CA  1 
ATOM   2452  C  C   . PHE A 1 355 ? 133.477 128.351 154.389 1.00 53.25  ?  344 PHE A C   1 
ATOM   2453  O  O   . PHE A 1 355 ? 133.348 127.745 153.347 1.00 53.25  ?  344 PHE A O   1 
ATOM   2454  C  CB  . PHE A 1 355 ? 132.226 130.468 154.795 1.00 53.25  ?  344 PHE A CB  1 
ATOM   2455  C  CG  . PHE A 1 355 ? 130.838 131.009 154.670 1.00 53.25  ?  344 PHE A CG  1 
ATOM   2456  C  CD1 . PHE A 1 355 ? 130.161 130.935 153.468 1.00 53.25  ?  344 PHE A CD1 1 
ATOM   2457  C  CD2 . PHE A 1 355 ? 130.201 131.572 155.758 1.00 53.25  ?  344 PHE A CD2 1 
ATOM   2458  C  CE1 . PHE A 1 355 ? 128.878 131.422 153.354 1.00 53.25  ?  344 PHE A CE1 1 
ATOM   2459  C  CE2 . PHE A 1 355 ? 128.917 132.059 155.651 1.00 53.25  ?  344 PHE A CE2 1 
ATOM   2460  C  CZ  . PHE A 1 355 ? 128.253 131.984 154.448 1.00 53.25  ?  344 PHE A CZ  1 
ATOM   2461  N  N   . GLY A 1 356 ? 134.648 128.492 154.993 1.00 50.89  ?  345 GLY A N   1 
ATOM   2462  C  CA  . GLY A 1 356 ? 135.845 127.896 154.459 1.00 50.89  ?  345 GLY A CA  1 
ATOM   2463  C  C   . GLY A 1 356 ? 135.718 126.393 154.464 1.00 50.89  ?  345 GLY A C   1 
ATOM   2464  O  O   . GLY A 1 356 ? 136.113 125.747 153.523 1.00 50.89  ?  345 GLY A O   1 
ATOM   2465  N  N   . ILE A 1 357 ? 135.179 125.831 155.533 1.00 48.68  ?  346 ILE A N   1 
ATOM   2466  C  CA  . ILE A 1 357 ? 135.001 124.394 155.593 1.00 48.68  ?  346 ILE A CA  1 
ATOM   2467  C  C   . ILE A 1 357 ? 134.014 123.896 154.544 1.00 48.68  ?  346 ILE A C   1 
ATOM   2468  O  O   . ILE A 1 357 ? 134.258 122.899 153.895 1.00 48.68  ?  346 ILE A O   1 
ATOM   2469  C  CB  . ILE A 1 357 ? 134.553 123.921 156.981 1.00 48.68  ?  346 ILE A CB  1 
ATOM   2470  C  CG1 . ILE A 1 357 ? 135.701 124.009 157.975 1.00 48.68  ?  346 ILE A CG1 1 
ATOM   2471  C  CG2 . ILE A 1 357 ? 134.064 122.494 156.915 1.00 48.68  ?  346 ILE A CG2 1 
ATOM   2472  C  CD1 . ILE A 1 357 ? 135.262 123.932 159.412 1.00 48.68  ?  346 ILE A CD1 1 
ATOM   2473  N  N   . ALA A 1 358 ? 132.905 124.600 154.371 1.00 47.87  ?  347 ALA A N   1 
ATOM   2474  C  CA  . ALA A 1 358 ? 131.911 124.209 153.388 1.00 47.87  ?  347 ALA A CA  1 
ATOM   2475  C  C   . ALA A 1 358 ? 132.432 124.276 151.960 1.00 47.87  ?  347 ALA A C   1 
ATOM   2476  O  O   . ALA A 1 358 ? 132.159 123.406 151.160 1.00 47.87  ?  347 ALA A O   1 
ATOM   2477  C  CB  . ALA A 1 358 ? 130.661 125.052 153.537 1.00 47.87  ?  347 ALA A CB  1 
ATOM   2478  N  N   . MET A 1 359 ? 133.150 125.337 151.628 1.00 49.95  ?  348 MET A N   1 
ATOM   2479  C  CA  . MET A 1 359 ? 133.717 125.473 150.300 1.00 49.95  ?  348 MET A CA  1 
ATOM   2480  C  C   . MET A 1 359 ? 134.811 124.449 150.022 1.00 49.95  ?  348 MET A C   1 
ATOM   2481  O  O   . MET A 1 359 ? 134.892 123.916 148.935 1.00 49.95  ?  348 MET A O   1 
ATOM   2482  C  CB  . MET A 1 359 ? 134.191 126.903 150.036 1.00 49.95  ?  348 MET A CB  1 
ATOM   2483  C  CG  . MET A 1 359 ? 133.101 127.971 150.150 1.00 49.95  ?  348 MET A CG  1 
ATOM   2484  S  SD  . MET A 1 359 ? 131.647 127.903 149.068 1.00 49.95  ?  348 MET A SD  1 
ATOM   2485  C  CE  . MET A 1 359 ? 130.485 126.887 149.974 1.00 49.95  ?  348 MET A CE  1 
ATOM   2486  N  N   . VAL A 1 360 ? 135.677 124.201 150.994 1.00 46.42  ?  349 VAL A N   1 
ATOM   2487  C  CA  . VAL A 1 360 ? 136.716 123.212 150.813 1.00 46.42  ?  349 VAL A CA  1 
ATOM   2488  C  C   . VAL A 1 360 ? 136.103 121.831 150.677 1.00 46.42  ?  349 VAL A C   1 
ATOM   2489  O  O   . VAL A 1 360 ? 136.527 121.049 149.856 1.00 46.42  ?  349 VAL A O   1 
ATOM   2490  C  CB  . VAL A 1 360 ? 137.780 123.238 151.930 1.00 46.42  ?  349 VAL A CB  1 
ATOM   2491  C  CG1 . VAL A 1 360 ? 138.671 122.016 151.840 1.00 46.42  ?  349 VAL A CG1 1 
ATOM   2492  C  CG2 . VAL A 1 360 ? 138.624 124.493 151.832 1.00 46.42  ?  349 VAL A CG2 1 
ATOM   2493  N  N   . ALA A 1 361 ? 135.089 121.534 151.475 1.00 44.60  ?  350 ALA A N   1 
ATOM   2494  C  CA  . ALA A 1 361 ? 134.466 120.238 151.395 1.00 44.60  ?  350 ALA A CA  1 
ATOM   2495  C  C   . ALA A 1 361 ? 133.845 120.037 150.027 1.00 44.60  ?  350 ALA A C   1 
ATOM   2496  O  O   . ALA A 1 361 ? 134.036 119.003 149.420 1.00 44.60  ?  350 ALA A O   1 
ATOM   2497  C  CB  . ALA A 1 361 ? 133.422 120.092 152.481 1.00 44.60  ?  350 ALA A CB  1 
ATOM   2498  N  N   . PHE A 1 362 ? 133.126 121.035 149.530 1.00 45.22  ?  351 PHE A N   1 
ATOM   2499  C  CA  . PHE A 1 362 ? 132.501 120.940 148.224 1.00 45.22  ?  351 PHE A CA  1 
ATOM   2500  C  C   . PHE A 1 362 ? 133.481 120.898 147.074 1.00 45.22  ?  351 PHE A C   1 
ATOM   2501  O  O   . PHE A 1 362 ? 133.318 120.132 146.149 1.00 45.22  ?  351 PHE A O   1 
ATOM   2502  C  CB  . PHE A 1 362 ? 131.477 122.048 147.994 1.00 45.22  ?  351 PHE A CB  1 
ATOM   2503  C  CG  . PHE A 1 362 ? 130.886 122.033 146.615 1.00 45.22  ?  351 PHE A CG  1 
ATOM   2504  C  CD1 . PHE A 1 362 ? 130.177 120.933 146.166 1.00 45.22  ?  351 PHE A CD1 1 
ATOM   2505  C  CD2 . PHE A 1 362 ? 131.061 123.098 145.764 1.00 45.22  ?  351 PHE A CD2 1 
ATOM   2506  C  CE1 . PHE A 1 362 ? 129.642 120.905 144.900 1.00 45.22  ?  351 PHE A CE1 1 
ATOM   2507  C  CE2 . PHE A 1 362 ? 130.528 123.075 144.498 1.00 45.22  ?  351 PHE A CE2 1 
ATOM   2508  C  CZ  . PHE A 1 362 ? 129.819 121.981 144.065 1.00 45.22  ?  351 PHE A CZ  1 
ATOM   2509  N  N   . ALA A 1 363 ? 134.511 121.723 147.143 1.00 44.65  ?  352 ALA A N   1 
ATOM   2510  C  CA  . ALA A 1 363 ? 135.490 121.774 146.080 1.00 44.65  ?  352 ALA A CA  1 
ATOM   2511  C  C   . ALA A 1 363 ? 136.223 120.465 145.899 1.00 44.65  ?  352 ALA A C   1 
ATOM   2512  O  O   . ALA A 1 363 ? 136.406 120.022 144.785 1.00 44.65  ?  352 ALA A O   1 
ATOM   2513  C  CB  . ALA A 1 363 ? 136.479 122.894 146.327 1.00 44.65  ?  352 ALA A CB  1 
ATOM   2514  N  N   . VAL A 1 364 ? 136.652 119.853 146.992 1.00 43.85  ?  353 VAL A N   1 
ATOM   2515  C  CA  . VAL A 1 364 ? 137.349 118.585 146.918 1.00 43.85  ?  353 VAL A CA  1 
ATOM   2516  C  C   . VAL A 1 364 ? 136.465 117.473 146.399 1.00 43.85  ?  353 VAL A C   1 
ATOM   2517  O  O   . VAL A 1 364 ? 136.876 116.685 145.566 1.00 43.85  ?  353 VAL A O   1 
ATOM   2518  C  CB  . VAL A 1 364 ? 137.889 118.160 148.296 1.00 43.85  ?  353 VAL A CB  1 
ATOM   2519  C  CG1 . VAL A 1 364 ? 138.437 116.749 148.248 1.00 43.85  ?  353 VAL A CG1 1 
ATOM   2520  C  CG2 . VAL A 1 364 ? 138.941 119.134 148.779 1.00 43.85  ?  353 VAL A CG2 1 
ATOM   2521  N  N   . ALA A 1 365 ? 135.242 117.420 146.899 1.00 43.55  ?  354 ALA A N   1 
ATOM   2522  C  CA  . ALA A 1 365 ? 134.316 116.387 146.494 1.00 43.55  ?  354 ALA A CA  1 
ATOM   2523  C  C   . ALA A 1 365 ? 133.950 116.478 145.040 1.00 43.55  ?  354 ALA A C   1 
ATOM   2524  O  O   . ALA A 1 365 ? 133.884 115.478 144.363 1.00 43.55  ?  354 ALA A O   1 
ATOM   2525  C  CB  . ALA A 1 365 ? 133.070 116.422 147.350 1.00 43.55  ?  354 ALA A CB  1 
ATOM   2526  N  N   . PHE A 1 366 ? 133.696 117.691 144.575 1.00 44.97  ?  355 PHE A N   1 
ATOM   2527  C  CA  . PHE A 1 366 ? 133.336 117.922 143.198 1.00 44.97  ?  355 PHE A CA  1 
ATOM   2528  C  C   . PHE A 1 366 ? 134.470 117.557 142.255 1.00 44.97  ?  355 PHE A C   1 
ATOM   2529  O  O   . PHE A 1 366 ? 134.236 117.037 141.187 1.00 44.97  ?  355 PHE A O   1 
ATOM   2530  C  CB  . PHE A 1 366 ? 132.860 119.357 142.971 1.00 44.97  ?  355 PHE A CB  1 
ATOM   2531  C  CG  . PHE A 1 366 ? 132.278 119.578 141.615 1.00 44.97  ?  355 PHE A CG  1 
ATOM   2532  C  CD1 . PHE A 1 366 ? 133.017 120.186 140.624 1.00 44.97  ?  355 PHE A CD1 1 
ATOM   2533  C  CD2 . PHE A 1 366 ? 131.005 119.138 141.319 1.00 44.97  ?  355 PHE A CD2 1 
ATOM   2534  C  CE1 . PHE A 1 366 ? 132.490 120.364 139.366 1.00 44.97  ?  355 PHE A CE1 1 
ATOM   2535  C  CE2 . PHE A 1 366 ? 130.472 119.313 140.062 1.00 44.97  ?  355 PHE A CE2 1 
ATOM   2536  C  CZ  . PHE A 1 366 ? 131.216 119.931 139.087 1.00 44.97  ?  355 PHE A CZ  1 
ATOM   2537  N  N   . SER A 1 367 ? 135.697 117.878 142.637 1.00 44.58  ?  356 SER A N   1 
ATOM   2538  C  CA  . SER A 1 367 ? 136.854 117.554 141.821 1.00 44.58  ?  356 SER A CA  1 
ATOM   2539  C  C   . SER A 1 367 ? 137.048 116.065 141.681 1.00 44.58  ?  356 SER A C   1 
ATOM   2540  O  O   . SER A 1 367 ? 137.323 115.578 140.602 1.00 44.58  ?  356 SER A O   1 
ATOM   2541  C  CB  . SER A 1 367 ? 138.112 118.154 142.428 1.00 44.58  ?  356 SER A CB  1 
ATOM   2542  O  OG  . SER A 1 367 ? 138.022 119.555 142.494 1.00 44.58  ?  356 SER A OG  1 
ATOM   2543  N  N   . VAL A 1 368 ? 136.924 115.347 142.786 1.00 44.34  ?  357 VAL A N   1 
ATOM   2544  C  CA  . VAL A 1 368 ? 137.061 113.902 142.790 1.00 44.34  ?  357 VAL A CA  1 
ATOM   2545  C  C   . VAL A 1 368 ? 135.947 113.253 141.990 1.00 44.34  ?  357 VAL A C   1 
ATOM   2546  O  O   . VAL A 1 368 ? 136.176 112.338 141.232 1.00 44.34  ?  357 VAL A O   1 
ATOM   2547  C  CB  . VAL A 1 368 ? 137.110 113.352 144.228 1.00 44.34  ?  357 VAL A CB  1 
ATOM   2548  C  CG1 . VAL A 1 368 ? 137.022 111.842 144.252 1.00 44.34  ?  357 VAL A CG1 1 
ATOM   2549  C  CG2 . VAL A 1 368 ? 138.371 113.817 144.923 1.00 44.34  ?  357 VAL A CG2 1 
ATOM   2550  N  N   . ALA A 1 369 ? 134.737 113.754 142.162 1.00 45.42  ?  358 ALA A N   1 
ATOM   2551  C  CA  . ALA A 1 369 ? 133.578 113.247 141.460 1.00 45.42  ?  358 ALA A CA  1 
ATOM   2552  C  C   . ALA A 1 369 ? 133.683 113.468 139.961 1.00 45.42  ?  358 ALA A C   1 
ATOM   2553  O  O   . ALA A 1 369 ? 133.250 112.640 139.186 1.00 45.42  ?  358 ALA A O   1 
ATOM   2554  C  CB  . ALA A 1 369 ? 132.306 113.854 142.016 1.00 45.42  ?  358 ALA A CB  1 
ATOM   2555  N  N   . SER A 1 370 ? 134.237 114.609 139.572 1.00 46.62  ?  359 SER A N   1 
ATOM   2556  C  CA  . SER A 1 370 ? 134.409 114.985 138.177 1.00 46.62  ?  359 SER A CA  1 
ATOM   2557  C  C   . SER A 1 370 ? 135.311 114.045 137.422 1.00 46.62  ?  359 SER A C   1 
ATOM   2558  O  O   . SER A 1 370 ? 135.093 113.780 136.257 1.00 46.62  ?  359 SER A O   1 
ATOM   2559  C  CB  . SER A 1 370 ? 134.971 116.390 138.065 1.00 46.62  ?  359 SER A CB  1 
ATOM   2560  O  OG  . SER A 1 370 ? 133.944 117.340 138.147 1.00 46.62  ?  359 SER A OG  1 
ATOM   2561  N  N   . VAL A 1 371 ? 136.358 113.577 138.075 1.00 46.07  ?  360 VAL A N   1 
ATOM   2562  C  CA  . VAL A 1 371 ? 137.275 112.673 137.437 1.00 46.07  ?  360 VAL A CA  1 
ATOM   2563  C  C   . VAL A 1 371 ? 136.548 111.405 137.055 1.00 46.07  ?  360 VAL A C   1 
ATOM   2564  O  O   . VAL A 1 371 ? 136.704 110.904 135.959 1.00 46.07  ?  360 VAL A O   1 
ATOM   2565  C  CB  . VAL A 1 371 ? 138.414 112.308 138.403 1.00 46.07  ?  360 VAL A CB  1 
ATOM   2566  C  CG1 . VAL A 1 371 ? 139.227 111.145 137.880 1.00 46.07  ?  360 VAL A CG1 1 
ATOM   2567  C  CG2 . VAL A 1 371 ? 139.282 113.511 138.698 1.00 46.07  ?  360 VAL A CG2 1 
ATOM   2568  N  N   . TYR A 1 372 ? 135.768 110.878 137.981 1.00 46.69  ?  361 TYR A N   1 
ATOM   2569  C  CA  . TYR A 1 372 ? 134.981 109.683 137.740 1.00 46.69  ?  361 TYR A CA  1 
ATOM   2570  C  C   . TYR A 1 372 ? 133.823 109.840 136.786 1.00 46.69  ?  361 TYR A C   1 
ATOM   2571  O  O   . TYR A 1 372 ? 133.533 108.949 136.027 1.00 46.69  ?  361 TYR A O   1 
ATOM   2572  C  CB  . TYR A 1 372 ? 134.562 109.024 139.040 1.00 46.69  ?  361 TYR A CB  1 
ATOM   2573  C  CG  . TYR A 1 372 ? 135.750 108.631 139.835 1.00 46.69  ?  361 TYR A CG  1 
ATOM   2574  C  CD1 . TYR A 1 372 ? 136.722 107.828 139.277 1.00 46.69  ?  361 TYR A CD1 1 
ATOM   2575  C  CD2 . TYR A 1 372 ? 135.929 109.085 141.125 1.00 46.69  ?  361 TYR A CD2 1 
ATOM   2576  C  CE1 . TYR A 1 372 ? 137.840 107.483 139.984 1.00 46.69  ?  361 TYR A CE1 1 
ATOM   2577  C  CE2 . TYR A 1 372 ? 137.044 108.734 141.842 1.00 46.69  ?  361 TYR A CE2 1 
ATOM   2578  C  CZ  . TYR A 1 372 ? 137.989 107.932 141.258 1.00 46.69  ?  361 TYR A CZ  1 
ATOM   2579  O  OH  . TYR A 1 372 ? 139.099 107.569 141.942 1.00 46.69  ?  361 TYR A OH  1 
ATOM   2580  N  N   . SER A 1 373 ? 133.115 110.953 136.854 1.00 49.71  ?  362 SER A N   1 
ATOM   2581  C  CA  . SER A 1 373 ? 131.999 111.146 135.946 1.00 49.71  ?  362 SER A CA  1 
ATOM   2582  C  C   . SER A 1 373 ? 132.482 111.236 134.510 1.00 49.71  ?  362 SER A C   1 
ATOM   2583  O  O   . SER A 1 373 ? 131.851 110.732 133.602 1.00 49.71  ?  362 SER A O   1 
ATOM   2584  C  CB  . SER A 1 373 ? 131.149 112.348 136.334 1.00 49.71  ?  362 SER A CB  1 
ATOM   2585  O  OG  . SER A 1 373 ? 131.838 113.551 136.123 1.00 49.71  ?  362 SER A OG  1 
ATOM   2586  N  N   . LEU A 1 374 ? 133.592 111.925 134.312 1.00 50.18  ?  363 LEU A N   1 
ATOM   2587  C  CA  . LEU A 1 374 ? 134.187 112.056 133.005 1.00 50.18  ?  363 LEU A CA  1 
ATOM   2588  C  C   . LEU A 1 374 ? 134.659 110.708 132.487 1.00 50.18  ?  363 LEU A C   1 
ATOM   2589  O  O   . LEU A 1 374 ? 134.452 110.361 131.334 1.00 50.18  ?  363 LEU A O   1 
ATOM   2590  C  CB  . LEU A 1 374 ? 135.353 113.026 133.085 1.00 50.18  ?  363 LEU A CB  1 
ATOM   2591  C  CG  . LEU A 1 374 ? 136.202 113.226 131.836 1.00 50.18  ?  363 LEU A CG  1 
ATOM   2592  C  CD1 . LEU A 1 374 ? 135.375 113.851 130.734 1.00 50.18  ?  363 LEU A CD1 1 
ATOM   2593  C  CD2 . LEU A 1 374 ? 137.408 114.081 132.164 1.00 50.18  ?  363 LEU A CD2 1 
ATOM   2594  N  N   . LYS A 1 375 ? 135.283 109.947 133.368 1.00 51.95  ?  364 LYS A N   1 
ATOM   2595  C  CA  . LYS A 1 375 ? 135.798 108.626 133.064 1.00 51.95  ?  364 LYS A CA  1 
ATOM   2596  C  C   . LYS A 1 375 ? 134.718 107.619 132.716 1.00 51.95  ?  364 LYS A C   1 
ATOM   2597  O  O   . LYS A 1 375 ? 134.918 106.752 131.891 1.00 51.95  ?  364 LYS A O   1 
ATOM   2598  C  CB  . LYS A 1 375 ? 136.632 108.110 134.227 1.00 51.95  ?  364 LYS A CB  1 
ATOM   2599  C  CG  . LYS A 1 375 ? 137.066 106.680 134.057 1.00 51.95  ?  364 LYS A CG  1 
ATOM   2600  C  CD  . LYS A 1 375 ? 137.985 106.244 135.166 1.00 51.95  ?  364 LYS A CD  1 
ATOM   2601  C  CE  . LYS A 1 375 ? 138.599 104.905 134.836 1.00 51.95  ?  364 LYS A CE  1 
ATOM   2602  N  NZ  . LYS A 1 375 ? 139.134 104.236 136.041 1.00 51.95  1  364 LYS A NZ  1 
ATOM   2603  N  N   . TYR A 1 376 ? 133.596 107.692 133.413 1.00 51.21  ?  365 TYR A N   1 
ATOM   2604  C  CA  . TYR A 1 376 ? 132.495 106.776 133.193 1.00 51.21  ?  365 TYR A CA  1 
ATOM   2605  C  C   . TYR A 1 376 ? 131.336 107.358 132.413 1.00 51.21  ?  365 TYR A C   1 
ATOM   2606  O  O   . TYR A 1 376 ? 130.298 106.737 132.286 1.00 51.21  ?  365 TYR A O   1 
ATOM   2607  C  CB  . TYR A 1 376 ? 132.058 106.142 134.504 1.00 51.21  ?  365 TYR A CB  1 
ATOM   2608  C  CG  . TYR A 1 376 ? 133.149 105.301 135.077 1.00 51.21  ?  365 TYR A CG  1 
ATOM   2609  C  CD1 . TYR A 1 376 ? 133.934 105.763 136.114 1.00 51.21  ?  365 TYR A CD1 1 
ATOM   2610  C  CD2 . TYR A 1 376 ? 133.431 104.068 134.543 1.00 51.21  ?  365 TYR A CD2 1 
ATOM   2611  C  CE1 . TYR A 1 376 ? 134.952 105.006 136.622 1.00 51.21  ?  365 TYR A CE1 1 
ATOM   2612  C  CE2 . TYR A 1 376 ? 134.448 103.303 135.043 1.00 51.21  ?  365 TYR A CE2 1 
ATOM   2613  C  CZ  . TYR A 1 376 ? 135.195 103.781 136.080 1.00 51.21  ?  365 TYR A CZ  1 
ATOM   2614  O  OH  . TYR A 1 376 ? 136.200 103.029 136.569 1.00 51.21  ?  365 TYR A OH  1 
ATOM   2615  N  N   . ASP A 1 377 ? 131.522 108.565 131.908 1.00 54.82  ?  366 ASP A N   1 
ATOM   2616  C  CA  . ASP A 1 377 ? 130.523 109.227 131.084 1.00 54.82  ?  366 ASP A CA  1 
ATOM   2617  C  C   . ASP A 1 377 ? 129.106 109.363 131.631 1.00 54.82  ?  366 ASP A C   1 
ATOM   2618  O  O   . ASP A 1 377 ? 128.157 108.949 130.994 1.00 54.82  ?  366 ASP A O   1 
ATOM   2619  C  CB  . ASP A 1 377 ? 130.503 108.618 129.681 1.00 54.82  ?  366 ASP A CB  1 
ATOM   2620  C  CG  . ASP A 1 377 ? 129.792 109.492 128.670 1.00 54.82  ?  366 ASP A CG  1 
ATOM   2621  O  OD1 . ASP A 1 377 ? 129.484 108.997 127.574 1.00 54.82  ?  366 ASP A OD1 1 
ATOM   2622  O  OD2 . ASP A 1 377 ? 129.539 110.671 128.957 1.00 54.82  -1 366 ASP A OD2 1 
ATOM   2623  N  N   . TYR A 1 378 ? 128.964 109.886 132.837 1.00 52.01  ?  367 TYR A N   1 
ATOM   2624  C  CA  . TYR A 1 378 ? 127.643 110.108 133.390 1.00 52.01  ?  367 TYR A CA  1 
ATOM   2625  C  C   . TYR A 1 378 ? 127.599 111.524 133.927 1.00 52.01  ?  367 TYR A C   1 
ATOM   2626  O  O   . TYR A 1 378 ? 128.624 112.089 134.250 1.00 52.01  ?  367 TYR A O   1 
ATOM   2627  C  CB  . TYR A 1 378 ? 127.270 109.066 134.445 1.00 52.01  ?  367 TYR A CB  1 
ATOM   2628  C  CG  . TYR A 1 378 ? 128.180 109.000 135.638 1.00 52.01  ?  367 TYR A CG  1 
ATOM   2629  C  CD1 . TYR A 1 378 ? 129.238 108.109 135.673 1.00 52.01  ?  367 TYR A CD1 1 
ATOM   2630  C  CD2 . TYR A 1 378 ? 127.970 109.814 136.737 1.00 52.01  ?  367 TYR A CD2 1 
ATOM   2631  C  CE1 . TYR A 1 378 ? 130.061 108.038 136.761 1.00 52.01  ?  367 TYR A CE1 1 
ATOM   2632  C  CE2 . TYR A 1 378 ? 128.797 109.752 137.826 1.00 52.01  ?  367 TYR A CE2 1 
ATOM   2633  C  CZ  . TYR A 1 378 ? 129.835 108.858 137.830 1.00 52.01  ?  367 TYR A CZ  1 
ATOM   2634  O  OH  . TYR A 1 378 ? 130.665 108.790 138.908 1.00 52.01  ?  367 TYR A OH  1 
ATOM   2635  N  N   . PRO A 1 379 ? 126.409 112.119 133.977 1.00 53.93  ?  368 PRO A N   1 
ATOM   2636  C  CA  . PRO A 1 379 ? 126.291 113.499 134.449 1.00 53.93  ?  368 PRO A CA  1 
ATOM   2637  C  C   . PRO A 1 379 ? 126.389 113.700 135.963 1.00 53.93  ?  368 PRO A C   1 
ATOM   2638  O  O   . PRO A 1 379 ? 125.766 113.010 136.764 1.00 53.93  ?  368 PRO A O   1 
ATOM   2639  C  CB  . PRO A 1 379 ? 124.915 113.928 133.942 1.00 53.93  ?  368 PRO A CB  1 
ATOM   2640  C  CG  . PRO A 1 379 ? 124.165 112.667 133.728 1.00 53.93  ?  368 PRO A CG  1 
ATOM   2641  C  CD  . PRO A 1 379 ? 125.166 111.623 133.367 1.00 53.93  ?  368 PRO A CD  1 
ATOM   2642  N  N   . LEU A 1 380 ? 127.180 114.687 136.339 1.00 52.23  ?  369 LEU A N   1 
ATOM   2643  C  CA  . LEU A 1 380 ? 127.367 115.031 137.723 1.00 52.23  ?  369 LEU A CA  1 
ATOM   2644  C  C   . LEU A 1 380 ? 126.702 116.379 137.920 1.00 52.23  ?  369 LEU A C   1 
ATOM   2645  O  O   . LEU A 1 380 ? 127.047 117.340 137.260 1.00 52.23  ?  369 LEU A O   1 
ATOM   2646  C  CB  . LEU A 1 380 ? 128.852 115.147 137.992 1.00 52.23  ?  369 LEU A CB  1 
ATOM   2647  C  CG  . LEU A 1 380 ? 129.323 115.035 139.424 1.00 52.23  ?  369 LEU A CG  1 
ATOM   2648  C  CD1 . LEU A 1 380 ? 129.170 113.598 139.884 1.00 52.23  ?  369 LEU A CD1 1 
ATOM   2649  C  CD2 . LEU A 1 380 ? 130.766 115.488 139.464 1.00 52.23  ?  369 LEU A CD2 1 
ATOM   2650  N  N   . ASP A 1 381 ? 125.762 116.460 138.846 1.00 53.88  ?  370 ASP A N   1 
ATOM   2651  C  CA  . ASP A 1 381 ? 125.045 117.700 139.086 1.00 53.88  ?  370 ASP A CA  1 
ATOM   2652  C  C   . ASP A 1 381 ? 125.650 118.403 140.284 1.00 53.88  ?  370 ASP A C   1 
ATOM   2653  O  O   . ASP A 1 381 ? 125.505 117.949 141.398 1.00 53.88  ?  370 ASP A O   1 
ATOM   2654  C  CB  . ASP A 1 381 ? 123.584 117.360 139.354 1.00 53.88  ?  370 ASP A CB  1 
ATOM   2655  C  CG  . ASP A 1 381 ? 122.717 118.575 139.559 1.00 53.88  ?  370 ASP A CG  1 
ATOM   2656  O  OD1 . ASP A 1 381 ? 123.240 119.697 139.631 1.00 53.88  ?  370 ASP A OD1 1 
ATOM   2657  O  OD2 . ASP A 1 381 ? 121.490 118.404 139.650 1.00 53.88  -1 370 ASP A OD2 1 
ATOM   2658  N  N   . GLY A 1 382 ? 126.280 119.544 140.048 1.00 51.55  ?  371 GLY A N   1 
ATOM   2659  C  CA  . GLY A 1 382 ? 126.933 120.300 141.096 1.00 51.55  ?  371 GLY A CA  1 
ATOM   2660  C  C   . GLY A 1 382 ? 126.020 120.813 142.175 1.00 51.55  ?  371 GLY A C   1 
ATOM   2661  O  O   . GLY A 1 382 ? 126.385 120.846 143.330 1.00 51.55  ?  371 GLY A O   1 
ATOM   2662  N  N   . ASN A 1 383 ? 124.850 121.278 141.781 1.00 51.25  ?  372 ASN A N   1 
ATOM   2663  C  CA  . ASN A 1 383 ? 123.871 121.769 142.728 1.00 51.25  ?  372 ASN A CA  1 
ATOM   2664  C  C   . ASN A 1 383 ? 123.347 120.685 143.635 1.00 51.25  ?  372 ASN A C   1 
ATOM   2665  O  O   . ASN A 1 383 ? 123.110 120.924 144.796 1.00 51.25  ?  372 ASN A O   1 
ATOM   2666  C  CB  . ASN A 1 383 ? 122.746 122.476 142.002 1.00 51.25  ?  372 ASN A CB  1 
ATOM   2667  C  CG  . ASN A 1 383 ? 123.215 123.720 141.314 1.00 51.25  ?  372 ASN A CG  1 
ATOM   2668  O  OD1 . ASN A 1 383 ? 124.006 124.460 141.856 1.00 51.25  ?  372 ASN A OD1 1 
ATOM   2669  N  ND2 . ASN A 1 383 ? 122.748 123.941 140.110 1.00 51.25  ?  372 ASN A ND2 1 
ATOM   2670  N  N   . GLN A 1 384 ? 123.153 119.494 143.088 1.00 52.41  ?  373 GLN A N   1 
ATOM   2671  C  CA  . GLN A 1 384 ? 122.665 118.367 143.849 1.00 52.41  ?  373 GLN A CA  1 
ATOM   2672  C  C   . GLN A 1 384 ? 123.739 117.877 144.793 1.00 52.41  ?  373 GLN A C   1 
ATOM   2673  O  O   . GLN A 1 384 ? 123.442 117.404 145.869 1.00 52.41  ?  373 GLN A O   1 
ATOM   2674  C  CB  . GLN A 1 384 ? 122.189 117.242 142.931 1.00 52.41  ?  373 GLN A CB  1 
ATOM   2675  C  CG  . GLN A 1 384 ? 121.490 116.098 143.651 1.00 52.41  ?  373 GLN A CG  1 
ATOM   2676  C  CD  . GLN A 1 384 ? 120.363 116.576 144.540 1.00 52.41  ?  373 GLN A CD  1 
ATOM   2677  O  OE1 . GLN A 1 384 ? 119.901 117.686 144.404 1.00 52.41  ?  373 GLN A OE1 1 
ATOM   2678  N  NE2 . GLN A 1 384 ? 119.933 115.744 145.455 1.00 52.41  ?  373 GLN A NE2 1 
ATOM   2679  N  N   . GLU A 1 385 ? 124.994 117.992 144.387 1.00 51.16  ?  374 GLU A N   1 
ATOM   2680  C  CA  . GLU A 1 385 ? 126.104 117.594 145.228 1.00 51.16  ?  374 GLU A CA  1 
ATOM   2681  C  C   . GLU A 1 385 ? 126.139 118.455 146.469 1.00 51.16  ?  374 GLU A C   1 
ATOM   2682  O  O   . GLU A 1 385 ? 126.396 117.962 147.541 1.00 51.16  ?  374 GLU A O   1 
ATOM   2683  C  CB  . GLU A 1 385 ? 127.424 117.722 144.483 1.00 51.16  ?  374 GLU A CB  1 
ATOM   2684  C  CG  . GLU A 1 385 ? 127.499 116.879 143.235 1.00 51.16  ?  374 GLU A CG  1 
ATOM   2685  C  CD  . GLU A 1 385 ? 127.422 115.409 143.550 1.00 51.16  ?  374 GLU A CD  1 
ATOM   2686  O  OE1 . GLU A 1 385 ? 128.423 114.876 144.059 1.00 51.16  ?  374 GLU A OE1 1 
ATOM   2687  O  OE2 . GLU A 1 385 ? 126.372 114.790 143.297 1.00 51.16  -1 374 GLU A OE2 1 
ATOM   2688  N  N   . LEU A 1 386 ? 125.904 119.751 146.319 1.00 47.99  ?  375 LEU A N   1 
ATOM   2689  C  CA  . LEU A 1 386 ? 125.884 120.644 147.457 1.00 47.99  ?  375 LEU A CA  1 
ATOM   2690  C  C   . LEU A 1 386 ? 124.759 120.282 148.402 1.00 47.99  ?  375 LEU A C   1 
ATOM   2691  O  O   . LEU A 1 386 ? 124.923 120.297 149.596 1.00 47.99  ?  375 LEU A O   1 
ATOM   2692  C  CB  . LEU A 1 386 ? 125.744 122.089 147.008 1.00 47.99  ?  375 LEU A CB  1 
ATOM   2693  C  CG  . LEU A 1 386 ? 127.035 122.820 146.687 1.00 47.99  ?  375 LEU A CG  1 
ATOM   2694  C  CD1 . LEU A 1 386 ? 126.768 124.094 145.922 1.00 47.99  ?  375 LEU A CD1 1 
ATOM   2695  C  CD2 . LEU A 1 386 ? 127.804 123.097 147.954 1.00 47.99  ?  375 LEU A CD2 1 
ATOM   2696  N  N   . ILE A 1 387 ? 123.608 119.952 147.850 1.00 48.79  ?  376 ILE A N   1 
ATOM   2697  C  CA  . ILE A 1 387 ? 122.470 119.557 148.643 1.00 48.79  ?  376 ILE A CA  1 
ATOM   2698  C  C   . ILE A 1 387 ? 122.747 118.265 149.382 1.00 48.79  ?  376 ILE A C   1 
ATOM   2699  O  O   . ILE A 1 387 ? 122.476 118.167 150.555 1.00 48.79  ?  376 ILE A O   1 
ATOM   2700  C  CB  . ILE A 1 387 ? 121.215 119.395 147.769 1.00 48.79  ?  376 ILE A CB  1 
ATOM   2701  C  CG1 . ILE A 1 387 ? 120.657 120.761 147.400 1.00 48.79  ?  376 ILE A CG1 1 
ATOM   2702  C  CG2 . ILE A 1 387 ? 120.154 118.581 148.484 1.00 48.79  ?  376 ILE A CG2 1 
ATOM   2703  C  CD1 . ILE A 1 387 ? 119.840 120.758 146.136 1.00 48.79  ?  376 ILE A CD1 1 
ATOM   2704  N  N   . ALA A 1 388 ? 123.281 117.275 148.680 1.00 47.69  ?  377 ALA A N   1 
ATOM   2705  C  CA  . ALA A 1 388 ? 123.590 115.977 149.261 1.00 47.69  ?  377 ALA A CA  1 
ATOM   2706  C  C   . ALA A 1 388 ? 124.679 116.041 150.309 1.00 47.69  ?  377 ALA A C   1 
ATOM   2707  O  O   . ALA A 1 388 ? 124.569 115.436 151.351 1.00 47.69  ?  377 ALA A O   1 
ATOM   2708  C  CB  . ALA A 1 388 ? 123.976 115.005 148.173 1.00 47.69  ?  377 ALA A CB  1 
ATOM   2709  N  N   . LEU A 1 389 ? 125.746 116.763 150.014 1.00 47.09  ?  378 LEU A N   1 
ATOM   2710  C  CA  . LEU A 1 389 ? 126.832 116.915 150.961 1.00 47.09  ?  378 LEU A CA  1 
ATOM   2711  C  C   . LEU A 1 389 ? 126.379 117.689 152.174 1.00 47.09  ?  378 LEU A C   1 
ATOM   2712  O  O   . LEU A 1 389 ? 126.768 117.380 153.275 1.00 47.09  ?  378 LEU A O   1 
ATOM   2713  C  CB  . LEU A 1 389 ? 128.055 117.543 150.315 1.00 47.09  ?  378 LEU A CB  1 
ATOM   2714  C  CG  . LEU A 1 389 ? 128.771 116.639 149.317 1.00 47.09  ?  378 LEU A CG  1 
ATOM   2715  C  CD1 . LEU A 1 389 ? 129.896 117.411 148.658 1.00 47.09  ?  378 LEU A CD1 1 
ATOM   2716  C  CD2 . LEU A 1 389 ? 129.283 115.364 149.962 1.00 47.09  ?  378 LEU A CD2 1 
ATOM   2717  N  N   . GLY A 1 390 ? 125.575 118.720 151.955 1.00 47.09  ?  379 GLY A N   1 
ATOM   2718  C  CA  . GLY A 1 390 ? 125.037 119.517 153.033 1.00 47.09  ?  379 GLY A CA  1 
ATOM   2719  C  C   . GLY A 1 390 ? 124.118 118.764 153.970 1.00 47.09  ?  379 GLY A C   1 
ATOM   2720  O  O   . GLY A 1 390 ? 124.221 118.907 155.164 1.00 47.09  ?  379 GLY A O   1 
ATOM   2721  N  N   . LEU A 1 391 ? 123.216 117.959 153.434 1.00 47.04  ?  380 LEU A N   1 
ATOM   2722  C  CA  . LEU A 1 391 ? 122.320 117.155 154.253 1.00 47.04  ?  380 LEU A CA  1 
ATOM   2723  C  C   . LEU A 1 391 ? 123.089 116.125 155.048 1.00 47.04  ?  380 LEU A C   1 
ATOM   2724  O  O   . LEU A 1 391 ? 122.738 115.815 156.169 1.00 47.04  ?  380 LEU A O   1 
ATOM   2725  C  CB  . LEU A 1 391 ? 121.254 116.463 153.414 1.00 47.04  ?  380 LEU A CB  1 
ATOM   2726  C  CG  . LEU A 1 391 ? 120.204 117.347 152.757 1.00 47.04  ?  380 LEU A CG  1 
ATOM   2727  C  CD1 . LEU A 1 391 ? 119.303 116.532 151.849 1.00 47.04  ?  380 LEU A CD1 1 
ATOM   2728  C  CD2 . LEU A 1 391 ? 119.397 118.100 153.801 1.00 47.04  ?  380 LEU A CD2 1 
ATOM   2729  N  N   . GLY A 1 392 ? 124.107 115.548 154.426 1.00 47.08  ?  381 GLY A N   1 
ATOM   2730  C  CA  . GLY A 1 392 ? 124.931 114.552 155.066 1.00 47.08  ?  381 GLY A CA  1 
ATOM   2731  C  C   . GLY A 1 392 ? 125.660 115.130 156.244 1.00 47.08  ?  381 GLY A C   1 
ATOM   2732  O  O   . GLY A 1 392 ? 125.785 114.486 157.255 1.00 47.08  ?  381 GLY A O   1 
ATOM   2733  N  N   . ASN A 1 393 ? 126.177 116.337 156.084 1.00 46.79  ?  382 ASN A N   1 
ATOM   2734  C  CA  . ASN A 1 393 ? 126.866 117.041 157.148 1.00 46.79  ?  382 ASN A CA  1 
ATOM   2735  C  C   . ASN A 1 393 ? 125.984 117.445 158.307 1.00 46.79  ?  382 ASN A C   1 
ATOM   2736  O  O   . ASN A 1 393 ? 126.400 117.387 159.446 1.00 46.79  ?  382 ASN A O   1 
ATOM   2737  C  CB  . ASN A 1 393 ? 127.649 118.229 156.611 1.00 46.79  ?  382 ASN A CB  1 
ATOM   2738  C  CG  . ASN A 1 393 ? 129.028 117.840 156.158 1.00 46.79  ?  382 ASN A CG  1 
ATOM   2739  O  OD1 . ASN A 1 393 ? 129.573 116.843 156.602 1.00 46.79  ?  382 ASN A OD1 1 
ATOM   2740  N  ND2 . ASN A 1 393 ? 129.595 118.618 155.269 1.00 46.79  ?  382 ASN A ND2 1 
ATOM   2741  N  N   . ILE A 1 394 ? 124.778 117.899 158.005 1.00 46.92  ?  383 ILE A N   1 
ATOM   2742  C  CA  . ILE A 1 394 ? 123.834 118.293 159.022 1.00 46.92  ?  383 ILE A CA  1 
ATOM   2743  C  C   . ILE A 1 394 ? 123.464 117.091 159.864 1.00 46.92  ?  383 ILE A C   1 
ATOM   2744  O  O   . ILE A 1 394 ? 123.422 117.179 161.069 1.00 46.92  ?  383 ILE A O   1 
ATOM   2745  C  CB  . ILE A 1 394 ? 122.565 118.895 158.390 1.00 46.92  ?  383 ILE A CB  1 
ATOM   2746  C  CG1 . ILE A 1 394 ? 122.878 120.266 157.796 1.00 46.92  ?  383 ILE A CG1 1 
ATOM   2747  C  CG2 . ILE A 1 394 ? 121.451 119.000 159.414 1.00 46.92  ?  383 ILE A CG2 1 
ATOM   2748  C  CD1 . ILE A 1 394 ? 121.857 120.775 156.810 1.00 46.92  ?  383 ILE A CD1 1 
ATOM   2749  N  N   . VAL A 1 395 ? 123.201 115.965 159.221 1.00 48.24  ?  384 VAL A N   1 
ATOM   2750  C  CA  . VAL A 1 395 ? 122.866 114.735 159.917 1.00 48.24  ?  384 VAL A CA  1 
ATOM   2751  C  C   . VAL A 1 395 ? 124.039 114.211 160.726 1.00 48.24  ?  384 VAL A C   1 
ATOM   2752  O  O   . VAL A 1 395 ? 123.869 113.693 161.807 1.00 48.24  ?  384 VAL A O   1 
ATOM   2753  C  CB  . VAL A 1 395 ? 122.338 113.653 158.955 1.00 48.24  ?  384 VAL A CB  1 
ATOM   2754  C  CG1 . VAL A 1 395 ? 122.118 112.342 159.678 1.00 48.24  ?  384 VAL A CG1 1 
ATOM   2755  C  CG2 . VAL A 1 395 ? 121.047 114.108 158.311 1.00 48.24  ?  384 VAL A CG2 1 
ATOM   2756  N  N   . CYS A 1 396 ? 125.230 114.300 160.160 1.00 50.53  ?  385 CYS A N   1 
ATOM   2757  C  CA  . CYS A 1 396 ? 126.427 113.862 160.834 1.00 50.53  ?  385 CYS A CA  1 
ATOM   2758  C  C   . CYS A 1 396 ? 126.702 114.709 162.067 1.00 50.53  ?  385 CYS A C   1 
ATOM   2759  O  O   . CYS A 1 396 ? 126.970 114.183 163.122 1.00 50.53  ?  385 CYS A O   1 
ATOM   2760  C  CB  . CYS A 1 396 ? 127.591 113.953 159.858 1.00 50.53  ?  385 CYS A CB  1 
ATOM   2761  S  SG  . CYS A 1 396 ? 129.163 113.321 160.419 1.00 50.53  ?  385 CYS A SG  1 
ATOM   2762  N  N   . GLY A 1 397 ? 126.570 116.021 161.933 1.00 51.43  ?  386 GLY A N   1 
ATOM   2763  C  CA  . GLY A 1 397 ? 126.799 116.941 163.023 1.00 51.43  ?  386 GLY A CA  1 
ATOM   2764  C  C   . GLY A 1 397 ? 125.833 116.723 164.162 1.00 51.43  ?  386 GLY A C   1 
ATOM   2765  O  O   . GLY A 1 397 ? 126.207 116.766 165.313 1.00 51.43  ?  386 GLY A O   1 
ATOM   2766  N  N   . VAL A 1 398 ? 124.582 116.459 163.834 1.00 51.46  ?  387 VAL A N   1 
ATOM   2767  C  CA  . VAL A 1 398 ? 123.550 116.207 164.823 1.00 51.46  ?  387 VAL A CA  1 
ATOM   2768  C  C   . VAL A 1 398 ? 123.842 114.961 165.648 1.00 51.46  ?  387 VAL A C   1 
ATOM   2769  O  O   . VAL A 1 398 ? 123.585 114.922 166.836 1.00 51.46  ?  387 VAL A O   1 
ATOM   2770  C  CB  . VAL A 1 398 ? 122.162 116.124 164.170 1.00 51.46  ?  387 VAL A CB  1 
ATOM   2771  C  CG1 . VAL A 1 398 ? 121.166 115.461 165.097 1.00 51.46  ?  387 VAL A CG1 1 
ATOM   2772  C  CG2 . VAL A 1 398 ? 121.683 117.507 163.785 1.00 51.46  ?  387 VAL A CG2 1 
ATOM   2773  N  N   . PHE A 1 399 ? 124.398 113.947 165.006 1.00 51.66  ?  388 PHE A N   1 
ATOM   2774  C  CA  . PHE A 1 399 ? 124.720 112.694 165.651 1.00 51.66  ?  388 PHE A CA  1 
ATOM   2775  C  C   . PHE A 1 399 ? 126.145 112.592 166.166 1.00 51.66  ?  388 PHE A C   1 
ATOM   2776  O  O   . PHE A 1 399 ? 126.629 111.500 166.438 1.00 51.66  ?  388 PHE A O   1 
ATOM   2777  C  CB  . PHE A 1 399 ? 124.331 111.532 164.767 1.00 51.66  ?  388 PHE A CB  1 
ATOM   2778  C  CG  . PHE A 1 399 ? 122.860 111.298 164.727 1.00 51.66  ?  388 PHE A CG  1 
ATOM   2779  C  CD1 . PHE A 1 399 ? 122.109 111.742 163.664 1.00 51.66  ?  388 PHE A CD1 1 
ATOM   2780  C  CD2 . PHE A 1 399 ? 122.224 110.677 165.775 1.00 51.66  ?  388 PHE A CD2 1 
ATOM   2781  C  CE1 . PHE A 1 399 ? 120.749 111.544 163.630 1.00 51.66  ?  388 PHE A CE1 1 
ATOM   2782  C  CE2 . PHE A 1 399 ? 120.864 110.471 165.750 1.00 51.66  ?  388 PHE A CE2 1 
ATOM   2783  C  CZ  . PHE A 1 399 ? 120.124 110.906 164.675 1.00 51.66  ?  388 PHE A CZ  1 
ATOM   2784  N  N   . ARG A 1 400 ? 126.799 113.751 166.224 1.00 56.62  ?  389 ARG A N   1 
ATOM   2785  C  CA  . ARG A 1 400 ? 128.157 113.992 166.740 1.00 56.62  ?  389 ARG A CA  1 
ATOM   2786  C  C   . ARG A 1 400 ? 129.384 113.654 165.913 1.00 56.62  ?  389 ARG A C   1 
ATOM   2787  O  O   . ARG A 1 400 ? 130.479 113.615 166.437 1.00 56.62  ?  389 ARG A O   1 
ATOM   2788  C  CB  . ARG A 1 400 ? 128.317 113.571 168.201 1.00 56.62  ?  389 ARG A CB  1 
ATOM   2789  C  CG  . ARG A 1 400 ? 127.227 114.136 169.077 1.00 56.62  ?  389 ARG A CG  1 
ATOM   2790  C  CD  . ARG A 1 400 ? 127.382 113.688 170.504 1.00 56.62  ?  389 ARG A CD  1 
ATOM   2791  N  NE  . ARG A 1 400 ? 126.081 113.525 171.125 1.00 56.62  ?  389 ARG A NE  1 
ATOM   2792  C  CZ  . ARG A 1 400 ? 125.877 113.568 172.430 1.00 56.62  ?  389 ARG A CZ  1 
ATOM   2793  N  NH1 . ARG A 1 400 ? 124.664 113.402 172.914 1.00 56.62  1  389 ARG A NH1 1 
ATOM   2794  N  NH2 . ARG A 1 400 ? 126.890 113.784 173.246 1.00 56.62  ?  389 ARG A NH2 1 
ATOM   2795  N  N   . GLY A 1 401 ? 129.200 113.406 164.630 1.00 51.68  ?  390 GLY A N   1 
ATOM   2796  C  CA  . GLY A 1 401 ? 130.303 113.168 163.724 1.00 51.68  ?  390 GLY A CA  1 
ATOM   2797  C  C   . GLY A 1 401 ? 130.860 114.496 163.244 1.00 51.68  ?  390 GLY A C   1 
ATOM   2798  O  O   . GLY A 1 401 ? 130.289 115.540 163.480 1.00 51.68  ?  390 GLY A O   1 
ATOM   2799  N  N   . PHE A 1 402 ? 132.005 114.480 162.594 1.00 47.37  ?  391 PHE A N   1 
ATOM   2800  C  CA  . PHE A 1 402 ? 132.563 115.719 162.070 1.00 47.37  ?  391 PHE A CA  1 
ATOM   2801  C  C   . PHE A 1 402 ? 132.412 115.812 160.555 1.00 47.37  ?  391 PHE A C   1 
ATOM   2802  O  O   . PHE A 1 402 ? 132.213 114.826 159.888 1.00 47.37  ?  391 PHE A O   1 
ATOM   2803  C  CB  . PHE A 1 402 ? 134.002 115.992 162.554 1.00 47.37  ?  391 PHE A CB  1 
ATOM   2804  C  CG  . PHE A 1 402 ? 134.950 114.849 162.371 1.00 47.37  ?  391 PHE A CG  1 
ATOM   2805  C  CD1 . PHE A 1 402 ? 135.725 114.753 161.237 1.00 47.37  ?  391 PHE A CD1 1 
ATOM   2806  C  CD2 . PHE A 1 402 ? 135.091 113.896 163.350 1.00 47.37  ?  391 PHE A CD2 1 
ATOM   2807  C  CE1 . PHE A 1 402 ? 136.604 113.713 161.079 1.00 47.37  ?  391 PHE A CE1 1 
ATOM   2808  C  CE2 . PHE A 1 402 ? 135.971 112.855 163.197 1.00 47.37  ?  391 PHE A CE2 1 
ATOM   2809  C  CZ  . PHE A 1 402 ? 136.723 112.761 162.056 1.00 47.37  ?  391 PHE A CZ  1 
ATOM   2810  N  N   . ALA A 1 403 ? 132.491 117.022 160.033 1.00 47.03  ?  392 ALA A N   1 
ATOM   2811  C  CA  . ALA A 1 403 ? 132.330 117.284 158.614 1.00 47.03  ?  392 ALA A CA  1 
ATOM   2812  C  C   . ALA A 1 403 ? 133.360 116.630 157.720 1.00 47.03  ?  392 ALA A C   1 
ATOM   2813  O  O   . ALA A 1 403 ? 134.532 116.577 158.038 1.00 47.03  ?  392 ALA A O   1 
ATOM   2814  C  CB  . ALA A 1 403 ? 132.333 118.781 158.372 1.00 47.03  ?  392 ALA A CB  1 
ATOM   2815  N  N   . GLY A 1 404 ? 132.896 116.079 156.613 1.00 47.03  ?  393 GLY A N   1 
ATOM   2816  C  CA  . GLY A 1 404 ? 133.771 115.488 155.633 1.00 47.03  ?  393 GLY A CA  1 
ATOM   2817  C  C   . GLY A 1 404 ? 133.029 115.347 154.337 1.00 47.03  ?  393 GLY A C   1 
ATOM   2818  O  O   . GLY A 1 404 ? 131.824 115.252 154.347 1.00 47.03  ?  393 GLY A O   1 
ATOM   2819  N  N   . SER A 1 405 ? 133.723 115.290 153.217 1.00 46.09  ?  394 SER A N   1 
ATOM   2820  C  CA  . SER A 1 405 ? 133.032 115.088 151.957 1.00 46.09  ?  394 SER A CA  1 
ATOM   2821  C  C   . SER A 1 405 ? 133.538 113.823 151.302 1.00 46.09  ?  394 SER A C   1 
ATOM   2822  O  O   . SER A 1 405 ? 132.840 112.840 151.229 1.00 46.09  ?  394 SER A O   1 
ATOM   2823  C  CB  . SER A 1 405 ? 133.202 116.282 151.032 1.00 46.09  ?  394 SER A CB  1 
ATOM   2824  O  OG  . SER A 1 405 ? 134.559 116.551 150.822 1.00 46.09  ?  394 SER A OG  1 
ATOM   2825  N  N   . THR A 1 406 ? 134.764 113.855 150.821 1.00 46.22  ?  395 THR A N   1 
ATOM   2826  C  CA  . THR A 1 406 ? 135.359 112.679 150.221 1.00 46.22  ?  395 THR A CA  1 
ATOM   2827  C  C   . THR A 1 406 ? 136.864 112.731 150.362 1.00 46.22  ?  395 THR A C   1 
ATOM   2828  O  O   . THR A 1 406 ? 137.450 113.789 150.304 1.00 46.22  ?  395 THR A O   1 
ATOM   2829  C  CB  . THR A 1 406 ? 134.961 112.522 148.732 1.00 46.22  ?  395 THR A CB  1 
ATOM   2830  O  OG1 . THR A 1 406 ? 135.306 111.216 148.286 1.00 46.22  ?  395 THR A OG1 1 
ATOM   2831  C  CG2 . THR A 1 406 ? 135.659 113.532 147.855 1.00 46.22  ?  395 THR A CG2 1 
ATOM   2832  N  N   . ALA A 1 407 ? 137.492 111.577 150.511 1.00 47.07  ?  396 ALA A N   1 
ATOM   2833  C  CA  . ALA A 1 407 ? 138.934 111.499 150.584 1.00 47.07  ?  396 ALA A CA  1 
ATOM   2834  C  C   . ALA A 1 407 ? 139.317 110.926 149.248 1.00 47.07  ?  396 ALA A C   1 
ATOM   2835  O  O   . ALA A 1 407 ? 138.741 109.950 148.819 1.00 47.07  ?  396 ALA A O   1 
ATOM   2836  C  CB  . ALA A 1 407 ? 139.392 110.586 151.702 1.00 47.07  ?  396 ALA A CB  1 
ATOM   2837  N  N   . LEU A 1 408 ? 140.291 111.533 148.590 1.00 49.67  ?  397 LEU A N   1 
ATOM   2838  C  CA  . LEU A 1 408 ? 140.733 111.081 147.287 1.00 49.67  ?  397 LEU A CA  1 
ATOM   2839  C  C   . LEU A 1 408 ? 141.260 109.662 147.339 1.00 49.67  ?  397 LEU A C   1 
ATOM   2840  O  O   . LEU A 1 408 ? 140.998 108.880 146.449 1.00 49.67  ?  397 LEU A O   1 
ATOM   2841  C  CB  . LEU A 1 408 ? 141.828 112.009 146.774 1.00 49.67  ?  397 LEU A CB  1 
ATOM   2842  C  CG  . LEU A 1 408 ? 142.566 111.611 145.502 1.00 49.67  ?  397 LEU A CG  1 
ATOM   2843  C  CD1 . LEU A 1 408 ? 141.711 111.846 144.277 1.00 49.67  ?  397 LEU A CD1 1 
ATOM   2844  C  CD2 . LEU A 1 408 ? 143.858 112.383 145.399 1.00 49.67  ?  397 LEU A CD2 1 
ATOM   2845  N  N   . SER A 1 409 ? 142.013 109.337 148.376 1.00 51.19  ?  398 SER A N   1 
ATOM   2846  C  CA  . SER A 1 409 ? 142.551 108.001 148.530 1.00 51.19  ?  398 SER A CA  1 
ATOM   2847  C  C   . SER A 1 409 ? 141.470 106.946 148.716 1.00 51.19  ?  398 SER A C   1 
ATOM   2848  O  O   . SER A 1 409 ? 141.568 105.877 148.155 1.00 51.19  ?  398 SER A O   1 
ATOM   2849  C  CB  . SER A 1 409 ? 143.550 107.954 149.682 1.00 51.19  ?  398 SER A CB  1 
ATOM   2850  O  OG  . SER A 1 409 ? 142.900 108.064 150.925 1.00 51.19  ?  398 SER A OG  1 
ATOM   2851  N  N   . ARG A 1 410 ? 140.466 107.239 149.534 1.00 47.12  ?  399 ARG A N   1 
ATOM   2852  C  CA  . ARG A 1 410 ? 139.342 106.336 149.773 1.00 47.12  ?  399 ARG A CA  1 
ATOM   2853  C  C   . ARG A 1 410 ? 138.479 106.167 148.529 1.00 47.12  ?  399 ARG A C   1 
ATOM   2854  O  O   . ARG A 1 410 ? 138.001 105.092 148.241 1.00 47.12  ?  399 ARG A O   1 
ATOM   2855  C  CB  . ARG A 1 410 ? 138.514 106.815 150.970 1.00 47.12  ?  399 ARG A CB  1 
ATOM   2856  C  CG  . ARG A 1 410 ? 137.726 105.738 151.696 1.00 47.12  ?  399 ARG A CG  1 
ATOM   2857  C  CD  . ARG A 1 410 ? 136.954 106.292 152.886 1.00 47.12  ?  399 ARG A CD  1 
ATOM   2858  N  NE  . ARG A 1 410 ? 136.256 107.533 152.566 1.00 47.12  ?  399 ARG A NE  1 
ATOM   2859  C  CZ  . ARG A 1 410 ? 136.535 108.719 153.085 1.00 47.12  ?  399 ARG A CZ  1 
ATOM   2860  N  NH1 . ARG A 1 410 ? 135.866 109.772 152.700 1.00 47.12  1  399 ARG A NH1 1 
ATOM   2861  N  NH2 . ARG A 1 410 ? 137.485 108.854 153.983 1.00 47.12  ?  399 ARG A NH2 1 
ATOM   2862  N  N   . SER A 1 411 ? 138.253 107.257 147.812 1.00 47.53  ?  400 SER A N   1 
ATOM   2863  C  CA  . SER A 1 411 ? 137.470 107.226 146.586 1.00 47.53  ?  400 SER A CA  1 
ATOM   2864  C  C   . SER A 1 411 ? 138.143 106.384 145.528 1.00 47.53  ?  400 SER A C   1 
ATOM   2865  O  O   . SER A 1 411 ? 137.499 105.652 144.798 1.00 47.53  ?  400 SER A O   1 
ATOM   2866  C  CB  . SER A 1 411 ? 137.224 108.625 146.066 1.00 47.53  ?  400 SER A CB  1 
ATOM   2867  O  OG  . SER A 1 411 ? 136.078 109.156 146.656 1.00 47.53  ?  400 SER A OG  1 
ATOM   2868  N  N   . ALA A 1 412 ? 139.460 106.503 145.455 1.00 47.94  ?  401 ALA A N   1 
ATOM   2869  C  CA  . ALA A 1 412 ? 140.249 105.740 144.523 1.00 47.94  ?  401 ALA A CA  1 
ATOM   2870  C  C   . ALA A 1 412 ? 140.101 104.273 144.850 1.00 47.94  ?  401 ALA A C   1 
ATOM   2871  O  O   . ALA A 1 412 ? 139.894 103.494 143.959 1.00 47.94  ?  401 ALA A O   1 
ATOM   2872  C  CB  . ALA A 1 412 ? 141.699 106.167 144.573 1.00 47.94  ?  401 ALA A CB  1 
ATOM   2873  N  N   . VAL A 1 413 ? 140.136 103.904 146.126 1.00 49.55  ?  402 VAL A N   1 
ATOM   2874  C  CA  . VAL A 1 413 ? 139.968 102.520 146.531 1.00 49.55  ?  402 VAL A CA  1 
ATOM   2875  C  C   . VAL A 1 413 ? 138.604 101.973 146.146 1.00 49.55  ?  402 VAL A C   1 
ATOM   2876  O  O   . VAL A 1 413 ? 138.519 100.889 145.628 1.00 49.55  ?  402 VAL A O   1 
ATOM   2877  C  CB  . VAL A 1 413 ? 140.160 102.346 148.055 1.00 49.55  ?  402 VAL A CB  1 
ATOM   2878  C  CG1 . VAL A 1 413 ? 139.672 100.986 148.515 1.00 49.55  ?  402 VAL A CG1 1 
ATOM   2879  C  CG2 . VAL A 1 413 ? 141.609 102.548 148.444 1.00 49.55  ?  402 VAL A CG2 1 
ATOM   2880  N  N   . GLN A 1 414 ? 137.540 102.737 146.338 1.00 49.10  ?  403 GLN A N   1 
ATOM   2881  C  CA  . GLN A 1 414 ? 136.210 102.261 145.998 1.00 49.10  ?  403 GLN A CA  1 
ATOM   2882  C  C   . GLN A 1 414 ? 136.134 101.987 144.505 1.00 49.10  ?  403 GLN A C   1 
ATOM   2883  O  O   . GLN A 1 414 ? 135.590 100.990 144.080 1.00 49.10  ?  403 GLN A O   1 
ATOM   2884  C  CB  . GLN A 1 414 ? 135.139 103.281 146.429 1.00 49.10  ?  403 GLN A CB  1 
ATOM   2885  C  CG  . GLN A 1 414 ? 133.697 102.832 146.238 1.00 49.10  ?  403 GLN A CG  1 
ATOM   2886  C  CD  . GLN A 1 414 ? 132.680 103.706 146.952 1.00 49.10  ?  403 GLN A CD  1 
ATOM   2887  O  OE1 . GLN A 1 414 ? 132.715 103.843 148.158 1.00 49.10  ?  403 GLN A OE1 1 
ATOM   2888  N  NE2 . GLN A 1 414 ? 131.752 104.276 146.206 1.00 49.10  ?  403 GLN A NE2 1 
ATOM   2889  N  N   . GLU A 1 415 ? 136.666 102.905 143.716 1.00 52.66  ?  404 GLU A N   1 
ATOM   2890  C  CA  . GLU A 1 415 ? 136.710 102.791 142.273 1.00 52.66  ?  404 GLU A CA  1 
ATOM   2891  C  C   . GLU A 1 415 ? 137.644 101.709 141.711 1.00 52.66  ?  404 GLU A C   1 
ATOM   2892  O  O   . GLU A 1 415 ? 137.271 100.965 140.818 1.00 52.66  ?  404 GLU A O   1 
ATOM   2893  C  CB  . GLU A 1 415 ? 137.000 104.167 141.681 1.00 52.66  ?  404 GLU A CB  1 
ATOM   2894  C  CG  . GLU A 1 415 ? 136.806 104.256 140.191 1.00 52.66  ?  404 GLU A CG  1 
ATOM   2895  C  CD  . GLU A 1 415 ? 138.063 103.908 139.436 1.00 52.66  ?  404 GLU A CD  1 
ATOM   2896  O  OE1 . GLU A 1 415 ? 139.162 104.243 139.906 1.00 52.66  ?  404 GLU A OE1 1 
ATOM   2897  O  OE2 . GLU A 1 415 ? 137.956 103.303 138.371 1.00 52.66  -1 404 GLU A OE2 1 
ATOM   2898  N  N   . SER A 1 416 ? 138.844 101.611 142.275 1.00 52.51  ?  405 SER A N   1 
ATOM   2899  C  CA  . SER A 1 416 ? 139.871 100.643 141.880 1.00 52.51  ?  405 SER A CA  1 
ATOM   2900  C  C   . SER A 1 416 ? 139.532 99.207  142.209 1.00 52.51  ?  405 SER A C   1 
ATOM   2901  O  O   . SER A 1 416 ? 140.038 98.287  141.591 1.00 52.51  ?  405 SER A O   1 
ATOM   2902  C  CB  . SER A 1 416 ? 141.231 101.004 142.458 1.00 52.51  ?  405 SER A CB  1 
ATOM   2903  O  OG  . SER A 1 416 ? 142.058 99.877  142.578 1.00 52.51  ?  405 SER A OG  1 
ATOM   2904  N  N   . THR A 1 417 ? 138.668 99.016  143.194 1.00 52.03  ?  406 THR A N   1 
ATOM   2905  C  CA  . THR A 1 417 ? 138.238 97.695  143.625 1.00 52.03  ?  406 THR A CA  1 
ATOM   2906  C  C   . THR A 1 417 ? 136.959 97.256  142.934 1.00 52.03  ?  406 THR A C   1 
ATOM   2907  O  O   . THR A 1 417 ? 136.359 96.260  143.308 1.00 52.03  ?  406 THR A O   1 
ATOM   2908  C  CB  . THR A 1 417 ? 138.108 97.587  145.150 1.00 52.03  ?  406 THR A CB  1 
ATOM   2909  O  OG1 . THR A 1 417 ? 137.310 98.662  145.631 1.00 52.03  ?  406 THR A OG1 1 
ATOM   2910  C  CG2 . THR A 1 417 ? 139.465 97.669  145.789 1.00 52.03  ?  406 THR A CG2 1 
ATOM   2911  N  N   . GLY A 1 418 ? 136.544 98.008  141.927 1.00 53.36  ?  407 GLY A N   1 
ATOM   2912  C  CA  . GLY A 1 418 ? 135.370 97.675  141.166 1.00 53.36  ?  407 GLY A CA  1 
ATOM   2913  C  C   . GLY A 1 418 ? 134.040 98.268  141.509 1.00 53.36  ?  407 GLY A C   1 
ATOM   2914  O  O   . GLY A 1 418 ? 133.050 97.795  141.001 1.00 53.36  ?  407 GLY A O   1 
ATOM   2915  N  N   . GLY A 1 419 ? 133.987 99.286  142.351 1.00 53.99  ?  408 GLY A N   1 
ATOM   2916  C  CA  . GLY A 1 419 ? 132.700 99.850  142.701 1.00 53.99  ?  408 GLY A CA  1 
ATOM   2917  C  C   . GLY A 1 419 ? 131.982 100.380 141.488 1.00 53.99  ?  408 GLY A C   1 
ATOM   2918  O  O   . GLY A 1 419 ? 132.563 101.032 140.653 1.00 53.99  ?  408 GLY A O   1 
ATOM   2919  N  N   . LYS A 1 420 ? 130.702 100.068 141.380 1.00 55.48  ?  409 LYS A N   1 
ATOM   2920  C  CA  . LYS A 1 420 ? 129.900 100.497 140.247 1.00 55.48  ?  409 LYS A CA  1 
ATOM   2921  C  C   . LYS A 1 420 ? 128.951 101.635 140.550 1.00 55.48  ?  409 LYS A C   1 
ATOM   2922  O  O   . LYS A 1 420 ? 128.821 102.571 139.784 1.00 55.48  ?  409 LYS A O   1 
ATOM   2923  C  CB  . LYS A 1 420 ? 129.098 99.309  139.733 1.00 55.48  ?  409 LYS A CB  1 
ATOM   2924  C  CG  . LYS A 1 420 ? 129.953 98.229  139.122 1.00 55.48  ?  409 LYS A CG  1 
ATOM   2925  C  CD  . LYS A 1 420 ? 130.595 98.743  137.856 1.00 55.48  ?  409 LYS A CD  1 
ATOM   2926  C  CE  . LYS A 1 420 ? 131.495 97.699  137.235 1.00 55.48  ?  409 LYS A CE  1 
ATOM   2927  N  NZ  . LYS A 1 420 ? 132.843 97.709  137.846 1.00 55.48  1  409 LYS A NZ  1 
ATOM   2928  N  N   . THR A 1 421 ? 128.290 101.538 141.687 1.00 54.96  ?  410 THR A N   1 
ATOM   2929  C  CA  . THR A 1 421 ? 127.321 102.523 142.108 1.00 54.96  ?  410 THR A CA  1 
ATOM   2930  C  C   . THR A 1 421 ? 127.605 102.938 143.519 1.00 54.96  ?  410 THR A C   1 
ATOM   2931  O  O   . THR A 1 421 ? 128.637 102.617 144.086 1.00 54.96  ?  410 THR A O   1 
ATOM   2932  C  CB  . THR A 1 421 ? 125.881 101.980 142.077 1.00 54.96  ?  410 THR A CB  1 
ATOM   2933  O  OG1 . THR A 1 421 ? 125.805 100.796 142.860 1.00 54.96  ?  410 THR A OG1 1 
ATOM   2934  C  CG2 . THR A 1 421 ? 125.451 101.659 140.679 1.00 54.96  ?  410 THR A CG2 1 
ATOM   2935  N  N   . GLN A 1 422 ? 126.622 103.614 144.100 1.00 51.18  ?  411 GLN A N   1 
ATOM   2936  C  CA  . GLN A 1 422 ? 126.657 104.112 145.468 1.00 51.18  ?  411 GLN A CA  1 
ATOM   2937  C  C   . GLN A 1 422 ? 126.196 103.065 146.492 1.00 51.18  ?  411 GLN A C   1 
ATOM   2938  O  O   . GLN A 1 422 ? 126.059 103.361 147.652 1.00 51.18  ?  411 GLN A O   1 
ATOM   2939  C  CB  . GLN A 1 422 ? 125.897 105.428 145.593 1.00 51.18  ?  411 GLN A CB  1 
ATOM   2940  C  CG  . GLN A 1 422 ? 126.634 106.516 146.354 1.00 51.18  ?  411 GLN A CG  1 
ATOM   2941  C  CD  . GLN A 1 422 ? 128.133 106.536 146.105 1.00 51.18  ?  411 GLN A CD  1 
ATOM   2942  O  OE1 . GLN A 1 422 ? 128.638 107.345 145.358 1.00 51.18  ?  411 GLN A OE1 1 
ATOM   2943  N  NE2 . GLN A 1 422 ? 128.841 105.654 146.755 1.00 51.18  ?  411 GLN A NE2 1 
ATOM   2944  N  N   . ILE A 1 423 ? 125.875 101.865 146.009 1.00 52.03  ?  412 ILE A N   1 
ATOM   2945  C  CA  . ILE A 1 423 ? 125.590 100.656 146.769 1.00 52.03  ?  412 ILE A CA  1 
ATOM   2946  C  C   . ILE A 1 423 ? 126.890 100.233 147.463 1.00 52.03  ?  412 ILE A C   1 
ATOM   2947  O  O   . ILE A 1 423 ? 126.861 99.684  148.542 1.00 52.03  ?  412 ILE A O   1 
ATOM   2948  C  CB  . ILE A 1 423 ? 125.058 99.514  145.880 1.00 52.03  ?  412 ILE A CB  1 
ATOM   2949  C  CG1 . ILE A 1 423 ? 123.606 99.765  145.483 1.00 52.03  ?  412 ILE A CG1 1 
ATOM   2950  C  CG2 . ILE A 1 423 ? 125.168 98.176  146.582 1.00 52.03  ?  412 ILE A CG2 1 
ATOM   2951  C  CD1 . ILE A 1 423 ? 122.669 99.912  146.654 1.00 52.03  ?  412 ILE A CD1 1 
ATOM   2952  N  N   . ALA A 1 424 ? 128.029 100.427 146.803 1.00 49.97  ?  413 ALA A N   1 
ATOM   2953  C  CA  . ALA A 1 424 ? 129.341 100.156 147.380 1.00 49.97  ?  413 ALA A CA  1 
ATOM   2954  C  C   . ALA A 1 424 ? 129.568 101.071 148.585 1.00 49.97  ?  413 ALA A C   1 
ATOM   2955  O  O   . ALA A 1 424 ? 130.167 100.673 149.569 1.00 49.97  ?  413 ALA A O   1 
ATOM   2956  C  CB  . ALA A 1 424 ? 130.428 100.370 146.349 1.00 49.97  ?  413 ALA A CB  1 
ATOM   2957  N  N   . GLY A 1 425 ? 129.150 102.324 148.470 1.00 48.89  ?  414 GLY A N   1 
ATOM   2958  C  CA  . GLY A 1 425 ? 129.230 103.268 149.558 1.00 48.89  ?  414 GLY A CA  1 
ATOM   2959  C  C   . GLY A 1 425 ? 128.354 102.832 150.717 1.00 48.89  ?  414 GLY A C   1 
ATOM   2960  O  O   . GLY A 1 425 ? 128.713 103.016 151.862 1.00 48.89  ?  414 GLY A O   1 
ATOM   2961  N  N   . LEU A 1 426 ? 127.170 102.315 150.413 1.00 49.67  ?  415 LEU A N   1 
ATOM   2962  C  CA  . LEU A 1 426 ? 126.260 101.817 151.431 1.00 49.67  ?  415 LEU A CA  1 
ATOM   2963  C  C   . LEU A 1 426 ? 126.841 100.624 152.169 1.00 49.67  ?  415 LEU A C   1 
ATOM   2964  O  O   . LEU A 1 426 ? 126.715 100.523 153.370 1.00 49.67  ?  415 LEU A O   1 
ATOM   2965  C  CB  . LEU A 1 426 ? 124.916 101.431 150.822 1.00 49.67  ?  415 LEU A CB  1 
ATOM   2966  C  CG  . LEU A 1 426 ? 124.032 100.466 151.615 1.00 49.67  ?  415 LEU A CG  1 
ATOM   2967  C  CD1 . LEU A 1 426 ? 123.527 101.070 152.910 1.00 49.67  ?  415 LEU A CD1 1 
ATOM   2968  C  CD2 . LEU A 1 426 ? 122.865 99.978  150.783 1.00 49.67  ?  415 LEU A CD2 1 
ATOM   2969  N  N   . ILE A 1 427 ? 127.466 99.714  151.438 1.00 50.31  ?  416 ILE A N   1 
ATOM   2970  C  CA  . ILE A 1 427 ? 128.088 98.535  152.021 1.00 50.31  ?  416 ILE A CA  1 
ATOM   2971  C  C   . ILE A 1 427 ? 129.249 98.928  152.921 1.00 50.31  ?  416 ILE A C   1 
ATOM   2972  O  O   . ILE A 1 427 ? 129.476 98.317  153.939 1.00 50.31  ?  416 ILE A O   1 
ATOM   2973  C  CB  . ILE A 1 427 ? 128.464 97.486  150.953 1.00 50.31  ?  416 ILE A CB  1 
ATOM   2974  C  CG1 . ILE A 1 427 ? 127.208 96.737  150.520 1.00 50.31  ?  416 ILE A CG1 1 
ATOM   2975  C  CG2 . ILE A 1 427 ? 129.487 96.496  151.478 1.00 50.31  ?  416 ILE A CG2 1 
ATOM   2976  C  CD1 . ILE A 1 427 ? 127.415 95.800  149.364 1.00 50.31  ?  416 ILE A CD1 1 
ATOM   2977  N  N   . GLY A 1 428 ? 129.998 99.939  152.512 1.00 49.68  ?  417 GLY A N   1 
ATOM   2978  C  CA  . GLY A 1 428 ? 131.105 100.444 153.285 1.00 49.68  ?  417 GLY A CA  1 
ATOM   2979  C  C   . GLY A 1 428 ? 130.634 101.000 154.607 1.00 49.68  ?  417 GLY A C   1 
ATOM   2980  O  O   . GLY A 1 428 ? 131.281 100.798 155.618 1.00 49.68  ?  417 GLY A O   1 
ATOM   2981  N  N   . ALA A 1 429 ? 129.508 101.707 154.585 1.00 48.77  ?  418 ALA A N   1 
ATOM   2982  C  CA  . ALA A 1 429 ? 128.894 102.291 155.772 1.00 48.77  ?  418 ALA A CA  1 
ATOM   2983  C  C   . ALA A 1 429 ? 128.461 101.203 156.737 1.00 48.77  ?  418 ALA A C   1 
ATOM   2984  O  O   . ALA A 1 429 ? 128.536 101.376 157.927 1.00 48.77  ?  418 ALA A O   1 
ATOM   2985  C  CB  . ALA A 1 429 ? 127.735 103.203 155.405 1.00 48.77  ?  418 ALA A CB  1 
ATOM   2986  N  N   . ILE A 1 430 ? 127.957 100.101 156.210 1.00 50.11  ?  419 ILE A N   1 
ATOM   2987  C  CA  . ILE A 1 430 ? 127.555 98.947  157.006 1.00 50.11  ?  419 ILE A CA  1 
ATOM   2988  C  C   . ILE A 1 430 ? 128.747 98.329  157.721 1.00 50.11  ?  419 ILE A C   1 
ATOM   2989  O  O   . ILE A 1 430 ? 128.608 97.806  158.803 1.00 50.11  ?  419 ILE A O   1 
ATOM   2990  C  CB  . ILE A 1 430 ? 126.829 97.875  156.187 1.00 50.11  ?  419 ILE A CB  1 
ATOM   2991  C  CG1 . ILE A 1 430 ? 125.521 98.428  155.648 1.00 50.11  ?  419 ILE A CG1 1 
ATOM   2992  C  CG2 . ILE A 1 430 ? 126.549 96.659  157.046 1.00 50.11  ?  419 ILE A CG2 1 
ATOM   2993  C  CD1 . ILE A 1 430 ? 124.857 97.521  154.645 1.00 50.11  ?  419 ILE A CD1 1 
ATOM   2994  N  N   . ILE A 1 431 ? 129.908 98.319  157.079 1.00 50.83  ?  420 ILE A N   1 
ATOM   2995  C  CA  . ILE A 1 431 ? 131.127 97.823  157.704 1.00 50.83  ?  420 ILE A CA  1 
ATOM   2996  C  C   . ILE A 1 431 ? 131.465 98.718  158.892 1.00 50.83  ?  420 ILE A C   1 
ATOM   2997  O  O   . ILE A 1 431 ? 131.837 98.242  159.947 1.00 50.83  ?  420 ILE A O   1 
ATOM   2998  C  CB  . ILE A 1 431 ? 132.323 97.853  156.737 1.00 50.83  ?  420 ILE A CB  1 
ATOM   2999  C  CG1 . ILE A 1 431 ? 132.122 96.880  155.582 1.00 50.83  ?  420 ILE A CG1 1 
ATOM   3000  C  CG2 . ILE A 1 431 ? 133.613 97.558  157.480 1.00 50.83  ?  420 ILE A CG2 1 
ATOM   3001  C  CD1 . ILE A 1 431 ? 132.213 95.433  155.975 1.00 50.83  ?  420 ILE A CD1 1 
ATOM   3002  N  N   . VAL A 1 432 ? 131.320 100.023 158.705 1.00 48.79  ?  421 VAL A N   1 
ATOM   3003  C  CA  . VAL A 1 432 ? 131.557 101.000 159.739 1.00 48.79  ?  421 VAL A CA  1 
ATOM   3004  C  C   . VAL A 1 432 ? 130.589 100.794 160.892 1.00 48.79  ?  421 VAL A C   1 
ATOM   3005  O  O   . VAL A 1 432 ? 130.966 100.890 162.041 1.00 48.79  ?  421 VAL A O   1 
ATOM   3006  C  CB  . VAL A 1 432 ? 131.396 102.419 159.187 1.00 48.79  ?  421 VAL A CB  1 
ATOM   3007  C  CG1 . VAL A 1 432 ? 131.467 103.440 160.302 1.00 48.79  ?  421 VAL A CG1 1 
ATOM   3008  C  CG2 . VAL A 1 432 ? 132.445 102.691 158.130 1.00 48.79  ?  421 VAL A CG2 1 
ATOM   3009  N  N   . LEU A 1 433 ? 129.341 100.504 160.563 1.00 49.58  ?  422 LEU A N   1 
ATOM   3010  C  CA  . LEU A 1 433 ? 128.308 100.249 161.531 1.00 49.58  ?  422 LEU A CA  1 
ATOM   3011  C  C   . LEU A 1 433 ? 128.639 99.042  162.374 1.00 49.58  ?  422 LEU A C   1 
ATOM   3012  O  O   . LEU A 1 433 ? 128.443 99.057  163.563 1.00 49.58  ?  422 LEU A O   1 
ATOM   3013  C  CB  . LEU A 1 433 ? 127.003 99.963  160.797 1.00 49.58  ?  422 LEU A CB  1 
ATOM   3014  C  CG  . LEU A 1 433 ? 125.783 99.655  161.651 1.00 49.58  ?  422 LEU A CG  1 
ATOM   3015  C  CD1 . LEU A 1 433 ? 125.091 100.934 162.068 1.00 49.58  ?  422 LEU A CD1 1 
ATOM   3016  C  CD2 . LEU A 1 433 ? 124.819 98.764  160.908 1.00 49.58  ?  422 LEU A CD2 1 
ATOM   3017  N  N   . ILE A 1 434 ? 129.148 97.993  161.751 1.00 51.73  ?  423 ILE A N   1 
ATOM   3018  C  CA  . ILE A 1 434 ? 129.494 96.774  162.457 1.00 51.73  ?  423 ILE A CA  1 
ATOM   3019  C  C   . ILE A 1 434 ? 130.589 97.051  163.465 1.00 51.73  ?  423 ILE A C   1 
ATOM   3020  O  O   . ILE A 1 434 ? 130.548 96.552  164.569 1.00 51.73  ?  423 ILE A O   1 
ATOM   3021  C  CB  . ILE A 1 434 ? 129.894 95.652  161.472 1.00 51.73  ?  423 ILE A CB  1 
ATOM   3022  C  CG1 . ILE A 1 434 ? 128.666 95.179  160.700 1.00 51.73  ?  423 ILE A CG1 1 
ATOM   3023  C  CG2 . ILE A 1 434 ? 130.543 94.482  162.194 1.00 51.73  ?  423 ILE A CG2 1 
ATOM   3024  C  CD1 . ILE A 1 434 ? 128.954 94.151  159.635 1.00 51.73  ?  423 ILE A CD1 1 
ATOM   3025  N  N   . VAL A 1 435 ? 131.577 97.844  163.074 1.00 51.52  ?  424 VAL A N   1 
ATOM   3026  C  CA  . VAL A 1 435 ? 132.655 98.219  163.972 1.00 51.52  ?  424 VAL A CA  1 
ATOM   3027  C  C   . VAL A 1 435 ? 132.122 99.054  165.118 1.00 51.52  ?  424 VAL A C   1 
ATOM   3028  O  O   . VAL A 1 435 ? 132.434 98.815  166.252 1.00 51.52  ?  424 VAL A O   1 
ATOM   3029  C  CB  . VAL A 1 435 ? 133.768 98.982  163.231 1.00 51.52  ?  424 VAL A CB  1 
ATOM   3030  C  CG1 . VAL A 1 435 ? 134.757 99.593  164.207 1.00 51.52  ?  424 VAL A CG1 1 
ATOM   3031  C  CG2 . VAL A 1 435 ? 134.477 98.063  162.261 1.00 51.52  ?  424 VAL A CG2 1 
ATOM   3032  N  N   . VAL A 1 436 ? 131.256 100.002 164.817 1.00 51.77  ?  425 VAL A N   1 
ATOM   3033  C  CA  . VAL A 1 436 ? 130.668 100.862 165.834 1.00 51.77  ?  425 VAL A CA  1 
ATOM   3034  C  C   . VAL A 1 436 ? 129.811 100.093 166.833 1.00 51.77  ?  425 VAL A C   1 
ATOM   3035  O  O   . VAL A 1 436 ? 129.810 100.402 168.010 1.00 51.77  ?  425 VAL A O   1 
ATOM   3036  C  CB  . VAL A 1 436 ? 129.821 101.977 165.198 1.00 51.77  ?  425 VAL A CB  1 
ATOM   3037  C  CG1 . VAL A 1 436 ? 128.899 102.607 166.219 1.00 51.77  ?  425 VAL A CG1 1 
ATOM   3038  C  CG2 . VAL A 1 436 ? 130.702 103.015 164.542 1.00 51.77  ?  425 VAL A CG2 1 
ATOM   3039  N  N   . LEU A 1 437 ? 129.030 99.140  166.350 1.00 53.59  ?  426 LEU A N   1 
ATOM   3040  C  CA  . LEU A 1 437 ? 128.186 98.337  167.213 1.00 53.59  ?  426 LEU A CA  1 
ATOM   3041  C  C   . LEU A 1 437 ? 128.776 97.084  167.850 1.00 53.59  ?  426 LEU A C   1 
ATOM   3042  O  O   . LEU A 1 437 ? 128.518 96.817  169.006 1.00 53.59  ?  426 LEU A O   1 
ATOM   3043  C  CB  . LEU A 1 437 ? 126.900 97.951  166.483 1.00 53.59  ?  426 LEU A CB  1 
ATOM   3044  C  CG  . LEU A 1 437 ? 125.948 99.089  166.137 1.00 53.59  ?  426 LEU A CG  1 
ATOM   3045  C  CD1 . LEU A 1 437 ? 124.654 98.551  165.574 1.00 53.59  ?  426 LEU A CD1 1 
ATOM   3046  C  CD2 . LEU A 1 437 ? 125.681 99.960  167.346 1.00 53.59  ?  426 LEU A CD2 1 
ATOM   3047  N  N   . ALA A 1 438 ? 129.561 96.310  167.114 1.00 54.35  ?  427 ALA A N   1 
ATOM   3048  C  CA  . ALA A 1 438 ? 130.052 95.051  167.669 1.00 54.35  ?  427 ALA A CA  1 
ATOM   3049  C  C   . ALA A 1 438 ? 131.543 94.753  167.771 1.00 54.35  ?  427 ALA A C   1 
ATOM   3050  O  O   . ALA A 1 438 ? 131.965 94.095  168.706 1.00 54.35  ?  427 ALA A O   1 
ATOM   3051  C  CB  . ALA A 1 438 ? 129.373 93.902  166.939 1.00 54.35  ?  427 ALA A CB  1 
ATOM   3052  N  N   . ILE A 1 439 ? 132.335 95.216  166.818 1.00 54.38  ?  428 ILE A N   1 
ATOM   3053  C  CA  . ILE A 1 439 ? 133.765 94.912  166.805 1.00 54.38  ?  428 ILE A CA  1 
ATOM   3054  C  C   . ILE A 1 439 ? 134.698 96.073  167.088 1.00 54.38  ?  428 ILE A C   1 
ATOM   3055  O  O   . ILE A 1 439 ? 135.847 96.053  166.707 1.00 54.38  ?  428 ILE A O   1 
ATOM   3056  C  CB  . ILE A 1 439 ? 134.203 94.129  165.549 1.00 54.38  ?  428 ILE A CB  1 
ATOM   3057  C  CG1 . ILE A 1 439 ? 134.173 95.005  164.306 1.00 54.38  ?  428 ILE A CG1 1 
ATOM   3058  C  CG2 . ILE A 1 439 ? 133.335 92.901  165.357 1.00 54.38  ?  428 ILE A CG2 1 
ATOM   3059  C  CD1 . ILE A 1 439 ? 134.801 94.335  163.107 1.00 54.38  ?  428 ILE A CD1 1 
ATOM   3060  N  N   . GLY A 1 440 ? 134.194 97.087  167.768 1.00 55.50  ?  429 GLY A N   1 
ATOM   3061  C  CA  . GLY A 1 440 ? 134.980 98.251  168.127 1.00 55.50  ?  429 GLY A CA  1 
ATOM   3062  C  C   . GLY A 1 440 ? 136.158 97.948  169.026 1.00 55.50  ?  429 GLY A C   1 
ATOM   3063  O  O   . GLY A 1 440 ? 137.187 98.582  168.922 1.00 55.50  ?  429 GLY A O   1 
ATOM   3064  N  N   . PHE A 1 441 ? 135.993 96.975  169.916 1.00 56.92  ?  430 PHE A N   1 
ATOM   3065  C  CA  . PHE A 1 441 ? 137.009 96.544  170.866 1.00 56.92  ?  430 PHE A CA  1 
ATOM   3066  C  C   . PHE A 1 441 ? 138.296 95.992  170.242 1.00 56.92  ?  430 PHE A C   1 
ATOM   3067  O  O   . PHE A 1 441 ? 139.336 96.013  170.875 1.00 56.92  ?  430 PHE A O   1 
ATOM   3068  C  CB  . PHE A 1 441 ? 136.414 95.526  171.833 1.00 56.92  ?  430 PHE A CB  1 
ATOM   3069  C  CG  . PHE A 1 441 ? 136.220 94.175  171.233 1.00 56.92  ?  430 PHE A CG  1 
ATOM   3070  C  CD1 . PHE A 1 441 ? 135.097 93.890  170.489 1.00 56.92  ?  430 PHE A CD1 1 
ATOM   3071  C  CD2 . PHE A 1 441 ? 137.176 93.201  171.391 1.00 56.92  ?  430 PHE A CD2 1 
ATOM   3072  C  CE1 . PHE A 1 441 ? 134.927 92.650  169.922 1.00 56.92  ?  430 PHE A CE1 1 
ATOM   3073  C  CE2 . PHE A 1 441 ? 137.014 91.959  170.823 1.00 56.92  ?  430 PHE A CE2 1 
ATOM   3074  C  CZ  . PHE A 1 441 ? 135.886 91.682  170.091 1.00 56.92  ?  430 PHE A CZ  1 
ATOM   3075  N  N   . LEU A 1 442 ? 138.224 95.457  169.029 1.00 57.59  ?  431 LEU A N   1 
ATOM   3076  C  CA  . LEU A 1 442 ? 139.382 94.925  168.333 1.00 57.59  ?  431 LEU A CA  1 
ATOM   3077  C  C   . LEU A 1 442 ? 140.433 96.002  168.079 1.00 57.59  ?  431 LEU A C   1 
ATOM   3078  O  O   . LEU A 1 442 ? 141.620 95.723  168.098 1.00 57.59  ?  431 LEU A O   1 
ATOM   3079  C  CB  . LEU A 1 442 ? 138.956 94.306  167.005 1.00 57.59  ?  431 LEU A CB  1 
ATOM   3080  C  CG  . LEU A 1 442 ? 138.273 92.944  166.995 1.00 57.59  ?  431 LEU A CG  1 
ATOM   3081  C  CD1 . LEU A 1 442 ? 137.863 92.592  165.581 1.00 57.59  ?  431 LEU A CD1 1 
ATOM   3082  C  CD2 . LEU A 1 442 ? 139.195 91.876  167.548 1.00 57.59  ?  431 LEU A CD2 1 
ATOM   3083  N  N   . LEU A 1 443 ? 139.992 97.210  167.762 1.00 59.01  ?  432 LEU A N   1 
ATOM   3084  C  CA  . LEU A 1 443 ? 140.879 98.332  167.514 1.00 59.01  ?  432 LEU A CA  1 
ATOM   3085  C  C   . LEU A 1 443 ? 141.476 98.969  168.767 1.00 59.01  ?  432 LEU A C   1 
ATOM   3086  O  O   . LEU A 1 443 ? 142.393 99.769  168.674 1.00 59.01  ?  432 LEU A O   1 
ATOM   3087  C  CB  . LEU A 1 443 ? 140.161 99.391  166.690 1.00 59.01  ?  432 LEU A CB  1 
ATOM   3088  C  CG  . LEU A 1 443 ? 139.624 98.899  165.349 1.00 59.01  ?  432 LEU A CG  1 
ATOM   3089  C  CD1 . LEU A 1 443 ? 138.478 99.782  164.906 1.00 59.01  ?  432 LEU A CD1 1 
ATOM   3090  C  CD2 . LEU A 1 443 ? 140.725 98.850  164.305 1.00 59.01  ?  432 LEU A CD2 1 
ATOM   3091  N  N   . ALA A 1 444 ? 140.944 98.633  169.932 1.00 60.19  ?  433 ALA A N   1 
ATOM   3092  C  CA  . ALA A 1 444 ? 141.415 99.187  171.199 1.00 60.19  ?  433 ALA A CA  1 
ATOM   3093  C  C   . ALA A 1 444 ? 142.922 99.207  171.417 1.00 60.19  ?  433 ALA A C   1 
ATOM   3094  O  O   . ALA A 1 444 ? 143.459 100.201 171.883 1.00 60.19  ?  433 ALA A O   1 
ATOM   3095  C  CB  . ALA A 1 444 ? 140.730 98.502  172.364 1.00 60.19  ?  433 ALA A CB  1 
ATOM   3096  N  N   . PRO A 1 445 ? 143.625 98.119  171.081 1.00 60.35  ?  434 PRO A N   1 
ATOM   3097  C  CA  . PRO A 1 445 ? 145.066 98.178  171.342 1.00 60.35  ?  434 PRO A CA  1 
ATOM   3098  C  C   . PRO A 1 445 ? 145.912 98.805  170.245 1.00 60.35  ?  434 PRO A C   1 
ATOM   3099  O  O   . PRO A 1 445 ? 147.119 98.745  170.342 1.00 60.35  ?  434 PRO A O   1 
ATOM   3100  C  CB  . PRO A 1 445 ? 145.439 96.712  171.507 1.00 60.35  ?  434 PRO A CB  1 
ATOM   3101  C  CG  . PRO A 1 445 ? 144.453 95.985  170.673 1.00 60.35  ?  434 PRO A CG  1 
ATOM   3102  C  CD  . PRO A 1 445 ? 143.182 96.768  170.712 1.00 60.35  ?  434 PRO A CD  1 
ATOM   3103  N  N   . LEU A 1 446 ? 145.309 99.404  169.232 1.00 58.88  ?  435 LEU A N   1 
ATOM   3104  C  CA  . LEU A 1 446 ? 146.084 100.002 168.171 1.00 58.88  ?  435 LEU A CA  1 
ATOM   3105  C  C   . LEU A 1 446 ? 146.657 101.348 168.564 1.00 58.88  ?  435 LEU A C   1 
ATOM   3106  O  O   . LEU A 1 446 ? 145.953 102.226 169.011 1.00 58.88  ?  435 LEU A O   1 
ATOM   3107  C  CB  . LEU A 1 446 ? 145.228 100.144 166.927 1.00 58.88  ?  435 LEU A CB  1 
ATOM   3108  C  CG  . LEU A 1 446 ? 145.865 100.833 165.734 1.00 58.88  ?  435 LEU A CG  1 
ATOM   3109  C  CD1 . LEU A 1 446 ? 146.866 99.915  165.055 1.00 58.88  ?  435 LEU A CD1 1 
ATOM   3110  C  CD2 . LEU A 1 446 ? 144.780 101.266 164.775 1.00 58.88  ?  435 LEU A CD2 1 
ATOM   3111  N  N   . GLN A 1 447 ? 147.957 101.498 168.364 1.00 58.97  ?  436 GLN A N   1 
ATOM   3112  C  CA  . GLN A 1 447 ? 148.662 102.720 168.685 1.00 58.97  ?  436 GLN A CA  1 
ATOM   3113  C  C   . GLN A 1 447 ? 148.295 103.882 167.791 1.00 58.97  ?  436 GLN A C   1 
ATOM   3114  O  O   . GLN A 1 447 ? 148.131 103.729 166.599 1.00 58.97  ?  436 GLN A O   1 
ATOM   3115  C  CB  . GLN A 1 447 ? 150.157 102.498 168.581 1.00 58.97  ?  436 GLN A CB  1 
ATOM   3116  C  CG  . GLN A 1 447 ? 150.683 101.408 169.477 1.00 58.97  ?  436 GLN A CG  1 
ATOM   3117  C  CD  . GLN A 1 447 ? 152.067 100.976 169.069 1.00 58.97  ?  436 GLN A CD  1 
ATOM   3118  O  OE1 . GLN A 1 447 ? 153.034 101.710 169.239 1.00 58.97  ?  436 GLN A OE1 1 
ATOM   3119  N  NE2 . GLN A 1 447 ? 152.169 99.777  168.523 1.00 58.97  ?  436 GLN A NE2 1 
ATOM   3120  N  N   . LYS A 1 448 ? 148.221 105.060 168.387 1.00 55.79  ?  437 LYS A N   1 
ATOM   3121  C  CA  . LYS A 1 448 ? 147.917 106.287 167.679 1.00 55.79  ?  437 LYS A CA  1 
ATOM   3122  C  C   . LYS A 1 448 ? 148.986 106.641 166.659 1.00 55.79  ?  437 LYS A C   1 
ATOM   3123  O  O   . LYS A 1 448 ? 148.685 107.218 165.636 1.00 55.79  ?  437 LYS A O   1 
ATOM   3124  C  CB  . LYS A 1 448 ? 147.667 107.434 168.641 1.00 55.79  ?  437 LYS A CB  1 
ATOM   3125  C  CG  . LYS A 1 448 ? 146.470 107.216 169.529 1.00 55.79  ?  437 LYS A CG  1 
ATOM   3126  C  CD  . LYS A 1 448 ? 146.127 108.495 170.247 1.00 55.79  ?  437 LYS A CD  1 
ATOM   3127  C  CE  . LYS A 1 448 ? 144.982 108.290 171.203 1.00 55.79  ?  437 LYS A CE  1 
ATOM   3128  N  NZ  . LYS A 1 448 ? 144.490 109.602 171.690 1.00 55.79  1  437 LYS A NZ  1 
ATOM   3129  N  N   . SER A 1 449 ? 150.240 106.341 166.973 1.00 56.48  ?  438 SER A N   1 
ATOM   3130  C  CA  . SER A 1 449 ? 151.361 106.600 166.085 1.00 56.48  ?  438 SER A CA  1 
ATOM   3131  C  C   . SER A 1 449 ? 151.242 105.825 164.790 1.00 56.48  ?  438 SER A C   1 
ATOM   3132  O  O   . SER A 1 449 ? 151.670 106.304 163.757 1.00 56.48  ?  438 SER A O   1 
ATOM   3133  C  CB  . SER A 1 449 ? 152.684 106.299 166.768 1.00 56.48  ?  438 SER A CB  1 
ATOM   3134  O  OG  . SER A 1 449 ? 152.823 104.923 166.985 1.00 56.48  ?  438 SER A OG  1 
ATOM   3135  N  N   . VAL A 1 450 ? 150.745 104.598 164.861 1.00 55.92  ?  439 VAL A N   1 
ATOM   3136  C  CA  . VAL A 1 450 ? 150.528 103.780 163.682 1.00 55.92  ?  439 VAL A CA  1 
ATOM   3137  C  C   . VAL A 1 450 ? 149.496 104.417 162.763 1.00 55.92  ?  439 VAL A C   1 
ATOM   3138  O  O   . VAL A 1 450 ? 149.663 104.420 161.562 1.00 55.92  ?  439 VAL A O   1 
ATOM   3139  C  CB  . VAL A 1 450 ? 150.044 102.378 164.053 1.00 55.92  ?  439 VAL A CB  1 
ATOM   3140  C  CG1 . VAL A 1 450 ? 149.623 101.619 162.813 1.00 55.92  ?  439 VAL A CG1 1 
ATOM   3141  C  CG2 . VAL A 1 450 ? 151.122 101.624 164.799 1.00 55.92  ?  439 VAL A CG2 1 
ATOM   3142  N  N   . LEU A 1 451 ? 148.425 104.949 163.335 1.00 55.02  ?  440 LEU A N   1 
ATOM   3143  C  CA  . LEU A 1 451 ? 147.383 105.623 162.570 1.00 55.02  ?  440 LEU A CA  1 
ATOM   3144  C  C   . LEU A 1 451 ? 147.937 106.863 161.908 1.00 55.02  ?  440 LEU A C   1 
ATOM   3145  O  O   . LEU A 1 451 ? 147.563 107.196 160.799 1.00 55.02  ?  440 LEU A O   1 
ATOM   3146  C  CB  . LEU A 1 451 ? 146.211 106.014 163.458 1.00 55.02  ?  440 LEU A CB  1 
ATOM   3147  C  CG  . LEU A 1 451 ? 145.232 104.930 163.881 1.00 55.02  ?  440 LEU A CG  1 
ATOM   3148  C  CD1 . LEU A 1 451 ? 144.241 105.488 164.876 1.00 55.02  ?  440 LEU A CD1 1 
ATOM   3149  C  CD2 . LEU A 1 451 ? 144.515 104.338 162.682 1.00 55.02  ?  440 LEU A CD2 1 
ATOM   3150  N  N   . ALA A 1 452 ? 148.773 107.579 162.647 1.00 55.00  ?  441 ALA A N   1 
ATOM   3151  C  CA  . ALA A 1 452 ? 149.442 108.770 162.175 1.00 55.00  ?  441 ALA A CA  1 
ATOM   3152  C  C   . ALA A 1 452 ? 150.403 108.442 161.041 1.00 55.00  ?  441 ALA A C   1 
ATOM   3153  O  O   . ALA A 1 452 ? 150.505 109.187 160.090 1.00 55.00  ?  441 ALA A O   1 
ATOM   3154  C  CB  . ALA A 1 452 ? 150.160 109.453 163.318 1.00 55.00  ?  441 ALA A CB  1 
ATOM   3155  N  N   . ALA A 1 453 ? 151.113 107.329 161.155 1.00 56.15  ?  442 ALA A N   1 
ATOM   3156  C  CA  . ALA A 1 453 ? 152.044 106.882 160.125 1.00 56.15  ?  442 ALA A CA  1 
ATOM   3157  C  C   . ALA A 1 453 ? 151.346 106.554 158.807 1.00 56.15  ?  442 ALA A C   1 
ATOM   3158  O  O   . ALA A 1 453 ? 151.906 106.765 157.749 1.00 56.15  ?  442 ALA A O   1 
ATOM   3159  C  CB  . ALA A 1 453 ? 152.868 105.708 160.603 1.00 56.15  ?  442 ALA A CB  1 
ATOM   3160  N  N   . LEU A 1 454 ? 150.160 105.967 158.872 1.00 56.82  ?  443 LEU A N   1 
ATOM   3161  C  CA  . LEU A 1 454 ? 149.392 105.654 157.675 1.00 56.82  ?  443 LEU A CA  1 
ATOM   3162  C  C   . LEU A 1 454 ? 148.986 106.912 156.937 1.00 56.82  ?  443 LEU A C   1 
ATOM   3163  O  O   . LEU A 1 454 ? 149.032 106.968 155.722 1.00 56.82  ?  443 LEU A O   1 
ATOM   3164  C  CB  . LEU A 1 454 ? 148.161 104.846 158.026 1.00 56.82  ?  443 LEU A CB  1 
ATOM   3165  C  CG  . LEU A 1 454 ? 148.444 103.463 158.582 1.00 56.82  ?  443 LEU A CG  1 
ATOM   3166  C  CD1 . LEU A 1 454 ? 147.154 102.878 159.104 1.00 56.82  ?  443 LEU A CD1 1 
ATOM   3167  C  CD2 . LEU A 1 454 ? 149.082 102.561 157.543 1.00 56.82  ?  443 LEU A CD2 1 
ATOM   3168  N  N   . ALA A 1 455 ? 148.587 107.926 157.689 1.00 56.51  ?  444 ALA A N   1 
ATOM   3169  C  CA  . ALA A 1 455 ? 148.198 109.211 157.139 1.00 56.51  ?  444 ALA A CA  1 
ATOM   3170  C  C   . ALA A 1 455 ? 149.381 109.879 156.439 1.00 56.51  ?  444 ALA A C   1 
ATOM   3171  O  O   . ALA A 1 455 ? 149.215 110.526 155.416 1.00 56.51  ?  444 ALA A O   1 
ATOM   3172  C  CB  . ALA A 1 455 ? 147.621 110.103 158.218 1.00 56.51  ?  444 ALA A CB  1 
ATOM   3173  N  N   . LEU A 1 456 ? 150.574 109.733 157.009 1.00 57.38  ?  445 LEU A N   1 
ATOM   3174  C  CA  . LEU A 1 456 ? 151.804 110.252 156.435 1.00 57.38  ?  445 LEU A CA  1 
ATOM   3175  C  C   . LEU A 1 456 ? 152.107 109.612 155.090 1.00 57.38  ?  445 LEU A C   1 
ATOM   3176  O  O   . LEU A 1 456 ? 152.618 110.268 154.196 1.00 57.38  ?  445 LEU A O   1 
ATOM   3177  C  CB  . LEU A 1 456 ? 152.981 110.072 157.384 1.00 57.38  ?  445 LEU A CB  1 
ATOM   3178  C  CG  . LEU A 1 456 ? 152.965 110.961 158.620 1.00 57.38  ?  445 LEU A CG  1 
ATOM   3179  C  CD1 . LEU A 1 456 ? 154.203 110.720 159.455 1.00 57.38  ?  445 LEU A CD1 1 
ATOM   3180  C  CD2 . LEU A 1 456 ? 152.819 112.428 158.270 1.00 57.38  ?  445 LEU A CD2 1 
ATOM   3181  N  N   . GLY A 1 457 ? 151.804 108.328 154.954 1.00 58.15  ?  446 GLY A N   1 
ATOM   3182  C  CA  . GLY A 1 457 ? 152.011 107.588 153.728 1.00 58.15  ?  446 GLY A CA  1 
ATOM   3183  C  C   . GLY A 1 457 ? 151.224 108.164 152.571 1.00 58.15  ?  446 GLY A C   1 
ATOM   3184  O  O   . GLY A 1 457 ? 151.704 108.170 151.455 1.00 58.15  ?  446 GLY A O   1 
ATOM   3185  N  N   . ASN A 1 458 ? 150.046 108.713 152.826 1.00 59.00  ?  447 ASN A N   1 
ATOM   3186  C  CA  . ASN A 1 458 ? 149.231 109.284 151.754 1.00 59.00  ?  447 ASN A CA  1 
ATOM   3187  C  C   . ASN A 1 458 ? 149.626 110.646 151.287 1.00 59.00  ?  447 ASN A C   1 
ATOM   3188  O  O   . ASN A 1 458 ? 149.138 111.143 150.289 1.00 59.00  ?  447 ASN A O   1 
ATOM   3189  C  CB  . ASN A 1 458 ? 147.793 109.353 152.174 1.00 59.00  ?  447 ASN A CB  1 
ATOM   3190  C  CG  . ASN A 1 458 ? 147.190 108.011 152.277 1.00 59.00  ?  447 ASN A CG  1 
ATOM   3191  O  OD1 . ASN A 1 458 ? 147.896 107.015 152.317 1.00 59.00  ?  447 ASN A OD1 1 
ATOM   3192  N  ND2 . ASN A 1 458 ? 145.882 107.956 152.317 1.00 59.00  ?  447 ASN A ND2 1 
ATOM   3193  N  N   . LEU A 1 459 ? 150.465 111.272 152.071 1.00 56.88  ?  448 LEU A N   1 
ATOM   3194  C  CA  . LEU A 1 459 ? 151.000 112.591 151.771 1.00 56.88  ?  448 LEU A CA  1 
ATOM   3195  C  C   . LEU A 1 459 ? 151.896 112.718 150.550 1.00 56.88  ?  448 LEU A C   1 
ATOM   3196  O  O   . LEU A 1 459 ? 152.031 113.800 150.009 1.00 56.88  ?  448 LEU A O   1 
ATOM   3197  C  CB  . LEU A 1 459 ? 151.756 113.122 152.980 1.00 56.88  ?  448 LEU A CB  1 
ATOM   3198  C  CG  . LEU A 1 459 ? 150.898 113.615 154.131 1.00 56.88  ?  448 LEU A CG  1 
ATOM   3199  C  CD1 . LEU A 1 459 ? 151.783 114.118 155.244 1.00 56.88  ?  448 LEU A CD1 1 
ATOM   3200  C  CD2 . LEU A 1 459 ? 149.949 114.691 153.661 1.00 56.88  ?  448 LEU A CD2 1 
ATOM   3201  N  N   . LYS A 1 460 ? 152.495 111.622 150.110 1.00 60.33  ?  449 LYS A N   1 
ATOM   3202  C  CA  . LYS A 1 460 ? 153.440 111.667 149.005 1.00 60.33  ?  449 LYS A CA  1 
ATOM   3203  C  C   . LYS A 1 460 ? 152.903 112.218 147.698 1.00 60.33  ?  449 LYS A C   1 
ATOM   3204  O  O   . LYS A 1 460 ? 153.617 112.913 147.005 1.00 60.33  ?  449 LYS A O   1 
ATOM   3205  C  CB  . LYS A 1 460 ? 154.014 110.282 148.740 1.00 60.33  ?  449 LYS A CB  1 
ATOM   3206  C  CG  . LYS A 1 460 ? 154.825 110.205 147.462 1.00 60.33  ?  449 LYS A CG  1 
ATOM   3207  C  CD  . LYS A 1 460 ? 154.686 108.846 146.814 1.00 60.33  ?  449 LYS A CD  1 
ATOM   3208  C  CE  . LYS A 1 460 ? 155.302 108.829 145.429 1.00 60.33  ?  449 LYS A CE  1 
ATOM   3209  N  NZ  . LYS A 1 460 ? 156.774 109.023 145.474 1.00 60.33  1  449 LYS A NZ  1 
ATOM   3210  N  N   . GLY A 1 461 ? 151.677 111.897 147.325 1.00 59.90  ?  450 GLY A N   1 
ATOM   3211  C  CA  . GLY A 1 461 ? 151.179 112.443 146.083 1.00 59.90  ?  450 GLY A CA  1 
ATOM   3212  C  C   . GLY A 1 461 ? 151.115 113.952 146.156 1.00 59.90  ?  450 GLY A C   1 
ATOM   3213  O  O   . GLY A 1 461 ? 151.530 114.636 145.240 1.00 59.90  ?  450 GLY A O   1 
ATOM   3214  N  N   . MET A 1 462 ? 150.600 114.468 147.262 1.00 59.76  ?  451 MET A N   1 
ATOM   3215  C  CA  . MET A 1 462 ? 150.509 115.905 147.485 1.00 59.76  ?  451 MET A CA  1 
ATOM   3216  C  C   . MET A 1 462 ? 151.864 116.580 147.632 1.00 59.76  ?  451 MET A C   1 
ATOM   3217  O  O   . MET A 1 462 ? 152.049 117.691 147.193 1.00 59.76  ?  451 MET A O   1 
ATOM   3218  C  CB  . MET A 1 462 ? 149.622 116.214 148.679 1.00 59.76  ?  451 MET A CB  1 
ATOM   3219  C  CG  . MET A 1 462 ? 148.158 116.388 148.343 1.00 59.76  ?  451 MET A CG  1 
ATOM   3220  S  SD  . MET A 1 462 ? 147.202 116.625 149.849 1.00 59.76  ?  451 MET A SD  1 
ATOM   3221  C  CE  . MET A 1 462 ? 147.600 115.112 150.711 1.00 59.76  ?  451 MET A CE  1 
ATOM   3222  N  N   . LEU A 1 463 ? 152.790 115.907 148.299 1.00 57.20  ?  452 LEU A N   1 
ATOM   3223  C  CA  . LEU A 1 463 ? 154.145 116.407 148.524 1.00 57.20  ?  452 LEU A CA  1 
ATOM   3224  C  C   . LEU A 1 463 ? 154.970 116.567 147.257 1.00 57.20  ?  452 LEU A C   1 
ATOM   3225  O  O   . LEU A 1 463 ? 155.819 117.438 147.170 1.00 57.20  ?  452 LEU A O   1 
ATOM   3226  C  CB  . LEU A 1 463 ? 154.876 115.592 149.583 1.00 57.20  ?  452 LEU A CB  1 
ATOM   3227  C  CG  . LEU A 1 463 ? 154.451 115.972 151.000 1.00 57.20  ?  452 LEU A CG  1 
ATOM   3228  C  CD1 . LEU A 1 463 ? 155.207 115.162 152.030 1.00 57.20  ?  452 LEU A CD1 1 
ATOM   3229  C  CD2 . LEU A 1 463 ? 154.624 117.457 151.248 1.00 57.20  ?  452 LEU A CD2 1 
ATOM   3230  N  N   . MET A 1 464 ? 154.675 115.749 146.248 1.00 59.93  ?  453 MET A N   1 
ATOM   3231  C  CA  . MET A 1 464 ? 155.330 115.763 144.933 1.00 59.93  ?  453 MET A CA  1 
ATOM   3232  C  C   . MET A 1 464 ? 154.974 116.949 144.028 1.00 59.93  ?  453 MET A C   1 
ATOM   3233  O  O   . MET A 1 464 ? 155.594 117.144 142.996 1.00 59.93  ?  453 MET A O   1 
ATOM   3234  C  CB  . MET A 1 464 ? 155.102 114.452 144.193 1.00 59.93  ?  453 MET A CB  1 
ATOM   3235  C  CG  . MET A 1 464 ? 156.044 113.344 144.617 1.00 59.93  ?  453 MET A CG  1 
ATOM   3236  S  SD  . MET A 1 464 ? 155.965 111.942 143.496 1.00 59.93  ?  453 MET A SD  1 
ATOM   3237  C  CE  . MET A 1 464 ? 154.197 111.698 143.387 1.00 59.93  ?  453 MET A CE  1 
ATOM   3238  N  N   . GLN A 1 465 ? 153.993 117.752 144.439 1.00 54.10  ?  454 GLN A N   1 
ATOM   3239  C  CA  . GLN A 1 465 ? 153.514 118.956 143.776 1.00 54.10  ?  454 GLN A CA  1 
ATOM   3240  C  C   . GLN A 1 465 ? 154.462 120.158 143.838 1.00 54.10  ?  454 GLN A C   1 
ATOM   3241  O  O   . GLN A 1 465 ? 154.168 121.179 143.269 1.00 54.10  ?  454 GLN A O   1 
ATOM   3242  C  CB  . GLN A 1 465 ? 152.149 119.339 144.306 1.00 54.10  ?  454 GLN A CB  1 
ATOM   3243  C  CG  . GLN A 1 465 ? 151.119 118.251 144.125 1.00 54.10  ?  454 GLN A CG  1 
ATOM   3244  C  CD  . GLN A 1 465 ? 149.719 118.761 144.301 1.00 54.10  ?  454 GLN A CD  1 
ATOM   3245  O  OE1 . GLN A 1 465 ? 148.997 118.931 143.336 1.00 54.10  ?  454 GLN A OE1 1 
ATOM   3246  N  NE2 . GLN A 1 465 ? 149.332 119.023 145.528 1.00 54.10  ?  454 GLN A NE2 1 
ATOM   3247  N  N   . PHE A 1 466 ? 155.565 120.063 144.581 1.00 52.20  ?  455 PHE A N   1 
ATOM   3248  C  CA  . PHE A 1 466 ? 156.622 121.078 144.646 1.00 52.20  ?  455 PHE A CA  1 
ATOM   3249  C  C   . PHE A 1 466 ? 157.316 121.268 143.283 1.00 52.20  ?  455 PHE A C   1 
ATOM   3250  O  O   . PHE A 1 466 ? 157.776 122.349 142.973 1.00 52.20  ?  455 PHE A O   1 
ATOM   3251  C  CB  . PHE A 1 466 ? 157.639 120.758 145.733 1.00 52.20  ?  455 PHE A CB  1 
ATOM   3252  C  CG  . PHE A 1 466 ? 157.238 121.231 147.091 1.00 52.20  ?  455 PHE A CG  1 
ATOM   3253  C  CD1 . PHE A 1 466 ? 157.138 122.576 147.364 1.00 52.20  ?  455 PHE A CD1 1 
ATOM   3254  C  CD2 . PHE A 1 466 ? 156.966 120.328 148.097 1.00 52.20  ?  455 PHE A CD2 1 
ATOM   3255  C  CE1 . PHE A 1 466 ? 156.762 123.012 148.613 1.00 52.20  ?  455 PHE A CE1 1 
ATOM   3256  C  CE2 . PHE A 1 466 ? 156.599 120.757 149.348 1.00 52.20  ?  455 PHE A CE2 1 
ATOM   3257  C  CZ  . PHE A 1 466 ? 156.500 122.101 149.608 1.00 52.20  ?  455 PHE A CZ  1 
ATOM   3258  N  N   . ALA A 1 467 ? 157.366 120.209 142.468 1.00 54.20  ?  456 ALA A N   1 
ATOM   3259  C  CA  . ALA A 1 467 ? 157.896 120.179 141.106 1.00 54.20  ?  456 ALA A CA  1 
ATOM   3260  C  C   . ALA A 1 467 ? 157.129 121.087 140.129 1.00 54.20  ?  456 ALA A C   1 
ATOM   3261  O  O   . ALA A 1 467 ? 157.670 121.525 139.131 1.00 54.20  ?  456 ALA A O   1 
ATOM   3262  C  CB  . ALA A 1 467 ? 157.913 118.757 140.595 1.00 54.20  ?  456 ALA A CB  1 
ATOM   3263  N  N   . GLU A 1 468 ? 155.861 121.345 140.422 1.00 55.40  ?  457 GLU A N   1 
ATOM   3264  C  CA  . GLU A 1 468 ? 154.991 122.223 139.670 1.00 55.40  ?  457 GLU A CA  1 
ATOM   3265  C  C   . GLU A 1 468 ? 155.519 123.643 139.611 1.00 55.40  ?  457 GLU A C   1 
ATOM   3266  O  O   . GLU A 1 468 ? 155.321 124.307 138.617 1.00 55.40  ?  457 GLU A O   1 
ATOM   3267  C  CB  . GLU A 1 468 ? 153.603 122.255 140.296 1.00 55.40  ?  457 GLU A CB  1 
ATOM   3268  C  CG  . GLU A 1 468 ? 152.615 121.303 139.664 1.00 55.40  ?  457 GLU A CG  1 
ATOM   3269  C  CD  . GLU A 1 468 ? 151.925 121.904 138.460 1.00 55.40  ?  457 GLU A CD  1 
ATOM   3270  O  OE1 . GLU A 1 468 ? 151.027 122.749 138.651 1.00 55.40  ?  457 GLU A OE1 1 
ATOM   3271  O  OE2 . GLU A 1 468 ? 152.273 121.524 137.328 1.00 55.40  -1 457 GLU A OE2 1 
ATOM   3272  N  N   . ILE A 1 469 ? 156.171 124.131 140.661 1.00 52.73  ?  458 ILE A N   1 
ATOM   3273  C  CA  . ILE A 1 469 ? 156.682 125.487 140.646 1.00 52.73  ?  458 ILE A CA  1 
ATOM   3274  C  C   . ILE A 1 469 ? 157.641 125.686 139.489 1.00 52.73  ?  458 ILE A C   1 
ATOM   3275  O  O   . ILE A 1 469 ? 157.555 126.678 138.790 1.00 52.73  ?  458 ILE A O   1 
ATOM   3276  C  CB  . ILE A 1 469 ? 157.510 125.769 141.907 1.00 52.73  ?  458 ILE A CB  1 
ATOM   3277  C  CG1 . ILE A 1 469 ? 156.658 125.629 143.162 1.00 52.73  ?  458 ILE A CG1 1 
ATOM   3278  C  CG2 . ILE A 1 469 ? 158.160 127.138 141.825 1.00 52.73  ?  458 ILE A CG2 1 
ATOM   3279  C  CD1 . ILE A 1 469 ? 157.455 125.726 144.440 1.00 52.73  ?  458 ILE A CD1 1 
ATOM   3280  N  N   . GLY A 1 470 ? 158.551 124.744 139.290 1.00 54.09  ?  459 GLY A N   1 
ATOM   3281  C  CA  . GLY A 1 470 ? 159.482 124.798 138.189 1.00 54.09  ?  459 GLY A CA  1 
ATOM   3282  C  C   . GLY A 1 470 ? 158.777 124.673 136.861 1.00 54.09  ?  459 GLY A C   1 
ATOM   3283  O  O   . GLY A 1 470 ? 159.149 125.313 135.904 1.00 54.09  ?  459 GLY A O   1 
ATOM   3284  N  N   . ARG A 1 471 ? 157.794 123.787 136.790 1.00 54.82  ?  460 ARG A N   1 
ATOM   3285  C  CA  . ARG A 1 471 ? 157.025 123.590 135.573 1.00 54.82  ?  460 ARG A CA  1 
ATOM   3286  C  C   . ARG A 1 471 ? 156.241 124.831 135.213 1.00 54.82  ?  460 ARG A C   1 
ATOM   3287  O  O   . ARG A 1 471 ? 156.220 125.251 134.075 1.00 54.82  ?  460 ARG A O   1 
ATOM   3288  C  CB  . ARG A 1 471 ? 156.047 122.438 135.749 1.00 54.82  ?  460 ARG A CB  1 
ATOM   3289  C  CG  . ARG A 1 471 ? 156.692 121.075 135.731 1.00 54.82  ?  460 ARG A CG  1 
ATOM   3290  C  CD  . ARG A 1 471 ? 155.655 119.990 135.544 1.00 54.82  ?  460 ARG A CD  1 
ATOM   3291  N  NE  . ARG A 1 471 ? 155.101 119.544 136.813 1.00 54.82  ?  460 ARG A NE  1 
ATOM   3292  C  CZ  . ARG A 1 471 ? 155.596 118.544 137.523 1.00 54.82  ?  460 ARG A CZ  1 
ATOM   3293  N  NH1 . ARG A 1 471 ? 155.033 118.211 138.669 1.00 54.82  1  460 ARG A NH1 1 
ATOM   3294  N  NH2 . ARG A 1 471 ? 156.655 117.886 137.087 1.00 54.82  ?  460 ARG A NH2 1 
ATOM   3295  N  N   . LEU A 1 472 ? 155.602 125.415 136.213 1.00 52.59  ?  461 LEU A N   1 
ATOM   3296  C  CA  . LEU A 1 472 ? 154.815 126.616 136.051 1.00 52.59  ?  461 LEU A CA  1 
ATOM   3297  C  C   . LEU A 1 472 ? 155.682 127.781 135.682 1.00 52.59  ?  461 LEU A C   1 
ATOM   3298  O  O   . LEU A 1 472 ? 155.295 128.613 134.905 1.00 52.59  ?  461 LEU A O   1 
ATOM   3299  C  CB  . LEU A 1 472 ? 153.995 126.926 137.296 1.00 52.59  ?  461 LEU A CB  1 
ATOM   3300  C  CG  . LEU A 1 472 ? 152.741 126.096 137.510 1.00 52.59  ?  461 LEU A CG  1 
ATOM   3301  C  CD1 . LEU A 1 472 ? 151.952 126.632 138.686 1.00 52.59  ?  461 LEU A CD1 1 
ATOM   3302  C  CD2 . LEU A 1 472 ? 151.893 126.059 136.256 1.00 52.59  ?  461 LEU A CD2 1 
ATOM   3303  N  N   . TRP A 1 473 ? 156.873 127.840 136.243 1.00 52.44  ?  462 TRP A N   1 
ATOM   3304  C  CA  . TRP A 1 473 ? 157.762 128.941 135.975 1.00 52.44  ?  462 TRP A CA  1 
ATOM   3305  C  C   . TRP A 1 473 ? 158.088 129.030 134.490 1.00 52.44  ?  462 TRP A C   1 
ATOM   3306  O  O   . TRP A 1 473 ? 158.120 130.120 133.932 1.00 52.44  ?  462 TRP A O   1 
ATOM   3307  C  CB  . TRP A 1 473 ? 159.035 128.766 136.791 1.00 52.44  ?  462 TRP A CB  1 
ATOM   3308  C  CG  . TRP A 1 473 ? 160.102 129.720 136.422 1.00 52.44  ?  462 TRP A CG  1 
ATOM   3309  C  CD1 . TRP A 1 473 ? 161.106 129.513 135.537 1.00 52.44  ?  462 TRP A CD1 1 
ATOM   3310  C  CD2 . TRP A 1 473 ? 160.274 131.043 136.923 1.00 52.44  ?  462 TRP A CD2 1 
ATOM   3311  N  NE1 . TRP A 1 473 ? 161.894 130.621 135.451 1.00 52.44  ?  462 TRP A NE1 1 
ATOM   3312  C  CE2 . TRP A 1 473 ? 161.405 131.579 136.295 1.00 52.44  ?  462 TRP A CE2 1 
ATOM   3313  C  CE3 . TRP A 1 473 ? 159.580 131.828 137.843 1.00 52.44  ?  462 TRP A CE3 1 
ATOM   3314  C  CZ2 . TRP A 1 473 ? 161.863 132.860 136.556 1.00 52.44  ?  462 TRP A CZ2 1 
ATOM   3315  C  CZ3 . TRP A 1 473 ? 160.034 133.096 138.099 1.00 52.44  ?  462 TRP A CZ3 1 
ATOM   3316  C  CH2 . TRP A 1 473 ? 161.164 133.602 137.458 1.00 52.44  ?  462 TRP A CH2 1 
ATOM   3317  N  N   . ARG A 1 474 ? 158.364 127.901 133.850 1.00 56.22  ?  463 ARG A N   1 
ATOM   3318  C  CA  . ARG A 1 474 ? 158.616 127.922 132.422 1.00 56.22  ?  463 ARG A CA  1 
ATOM   3319  C  C   . ARG A 1 474 ? 157.390 128.267 131.577 1.00 56.22  ?  463 ARG A C   1 
ATOM   3320  O  O   . ARG A 1 474 ? 157.481 129.042 130.647 1.00 56.22  ?  463 ARG A O   1 
ATOM   3321  C  CB  . ARG A 1 474 ? 159.189 126.590 131.970 1.00 56.22  ?  463 ARG A CB  1 
ATOM   3322  C  CG  . ARG A 1 474 ? 160.601 126.352 132.438 1.00 56.22  ?  463 ARG A CG  1 
ATOM   3323  C  CD  . ARG A 1 474 ? 161.142 125.043 131.898 1.00 56.22  ?  463 ARG A CD  1 
ATOM   3324  N  NE  . ARG A 1 474 ? 160.377 123.891 132.357 1.00 56.22  ?  463 ARG A NE  1 
ATOM   3325  C  CZ  . ARG A 1 474 ? 160.519 123.341 133.555 1.00 56.22  ?  463 ARG A CZ  1 
ATOM   3326  N  NH1 . ARG A 1 474 ? 159.794 122.291 133.897 1.00 56.22  1  463 ARG A NH1 1 
ATOM   3327  N  NH2 . ARG A 1 474 ? 161.390 123.847 134.413 1.00 56.22  ?  463 ARG A NH2 1 
ATOM   3328  N  N   . LYS A 1 475 ? 156.255 127.649 131.879 1.00 54.88  ?  464 LYS A N   1 
ATOM   3329  C  CA  . LYS A 1 475 ? 155.020 127.896 131.145 1.00 54.88  ?  464 LYS A CA  1 
ATOM   3330  C  C   . LYS A 1 475 ? 154.312 129.223 131.308 1.00 54.88  ?  464 LYS A C   1 
ATOM   3331  O  O   . LYS A 1 475 ? 153.890 129.816 130.334 1.00 54.88  ?  464 LYS A O   1 
ATOM   3332  C  CB  . LYS A 1 475 ? 153.990 126.831 131.482 1.00 54.88  ?  464 LYS A CB  1 
ATOM   3333  C  CG  . LYS A 1 475 ? 154.316 125.440 131.025 1.00 54.88  ?  464 LYS A CG  1 
ATOM   3334  C  CD  . LYS A 1 475 ? 153.200 124.535 131.482 1.00 54.88  ?  464 LYS A CD  1 
ATOM   3335  C  CE  . LYS A 1 475 ? 153.713 123.172 131.881 1.00 54.88  ?  464 LYS A CE  1 
ATOM   3336  N  NZ  . LYS A 1 475 ? 152.786 122.593 132.887 1.00 54.88  1  464 LYS A NZ  1 
ATOM   3337  N  N   . ASP A 1 476 ? 154.146 129.661 132.548 1.00 52.33  ?  465 ASP A N   1 
ATOM   3338  C  CA  . ASP A 1 476 ? 153.407 130.882 132.823 1.00 52.33  ?  465 ASP A CA  1 
ATOM   3339  C  C   . ASP A 1 476 ? 153.781 131.520 134.148 1.00 52.33  ?  465 ASP A C   1 
ATOM   3340  O  O   . ASP A 1 476 ? 153.452 131.001 135.189 1.00 52.33  ?  465 ASP A O   1 
ATOM   3341  C  CB  . ASP A 1 476 ? 151.922 130.530 132.819 1.00 52.33  ?  465 ASP A CB  1 
ATOM   3342  C  CG  . ASP A 1 476 ? 151.029 131.737 132.785 1.00 52.33  ?  465 ASP A CG  1 
ATOM   3343  O  OD1 . ASP A 1 476 ? 151.450 132.802 132.315 1.00 52.33  ?  465 ASP A OD1 1 
ATOM   3344  O  OD2 . ASP A 1 476 ? 149.882 131.620 133.217 1.00 52.33  -1 465 ASP A OD2 1 
ATOM   3345  N  N   . LYS A 1 477 ? 154.375 132.695 134.118 1.00 48.39  ?  466 LYS A N   1 
ATOM   3346  C  CA  . LYS A 1 477 ? 154.784 133.363 135.343 1.00 48.39  ?  466 LYS A CA  1 
ATOM   3347  C  C   . LYS A 1 477 ? 153.633 133.708 136.275 1.00 48.39  ?  466 LYS A C   1 
ATOM   3348  O  O   . LYS A 1 477 ? 153.807 133.680 137.469 1.00 48.39  ?  466 LYS A O   1 
ATOM   3349  C  CB  . LYS A 1 477 ? 155.613 134.604 135.042 1.00 48.39  ?  466 LYS A CB  1 
ATOM   3350  C  CG  . LYS A 1 477 ? 156.865 134.329 134.241 1.00 48.39  ?  466 LYS A CG  1 
ATOM   3351  C  CD  . LYS A 1 477 ? 157.963 133.763 135.107 1.00 48.39  ?  466 LYS A CD  1 
ATOM   3352  C  CE  . LYS A 1 477 ? 159.312 133.918 134.432 1.00 48.39  ?  466 LYS A CE  1 
ATOM   3353  N  NZ  . LYS A 1 477 ? 159.435 133.090 133.210 1.00 48.39  1  466 LYS A NZ  1 
ATOM   3354  N  N   . TYR A 1 478 ? 152.489 134.113 135.742 1.00 46.89  ?  467 TYR A N   1 
ATOM   3355  C  CA  . TYR A 1 478 ? 151.334 134.420 136.576 1.00 46.89  ?  467 TYR A CA  1 
ATOM   3356  C  C   . TYR A 1 478 ? 150.812 133.196 137.325 1.00 46.89  ?  467 TYR A C   1 
ATOM   3357  O  O   . TYR A 1 478 ? 150.385 133.310 138.452 1.00 46.89  ?  467 TYR A O   1 
ATOM   3358  C  CB  . TYR A 1 478 ? 150.210 135.064 135.775 1.00 46.89  ?  467 TYR A CB  1 
ATOM   3359  C  CG  . TYR A 1 478 ? 150.583 136.369 135.137 1.00 46.89  ?  467 TYR A CG  1 
ATOM   3360  C  CD1 . TYR A 1 478 ? 150.663 137.534 135.883 1.00 46.89  ?  467 TYR A CD1 1 
ATOM   3361  C  CD2 . TYR A 1 478 ? 150.858 136.438 133.790 1.00 46.89  ?  467 TYR A CD2 1 
ATOM   3362  C  CE1 . TYR A 1 478 ? 151.005 138.729 135.299 1.00 46.89  ?  467 TYR A CE1 1 
ATOM   3363  C  CE2 . TYR A 1 478 ? 151.192 137.628 133.199 1.00 46.89  ?  467 TYR A CE2 1 
ATOM   3364  C  CZ  . TYR A 1 478 ? 151.266 138.766 133.962 1.00 46.89  ?  467 TYR A CZ  1 
ATOM   3365  O  OH  . TYR A 1 478 ? 151.610 139.946 133.369 1.00 46.89  ?  467 TYR A OH  1 
ATOM   3366  N  N   . ASP A 1 479 ? 150.770 132.048 136.668 1.00 49.10  ?  468 ASP A N   1 
ATOM   3367  C  CA  . ASP A 1 479 ? 150.350 130.808 137.309 1.00 49.10  ?  468 ASP A CA  1 
ATOM   3368  C  C   . ASP A 1 479 ? 151.345 130.385 138.381 1.00 49.10  ?  468 ASP A C   1 
ATOM   3369  O  O   . ASP A 1 479 ? 150.970 129.841 139.396 1.00 49.10  ?  468 ASP A O   1 
ATOM   3370  C  CB  . ASP A 1 479 ? 150.086 129.698 136.298 1.00 49.10  ?  468 ASP A CB  1 
ATOM   3371  C  CG  . ASP A 1 479 ? 148.673 129.739 135.760 1.00 49.10  ?  468 ASP A CG  1 
ATOM   3372  O  OD1 . ASP A 1 479 ? 147.765 130.181 136.482 1.00 49.10  ?  468 ASP A OD1 1 
ATOM   3373  O  OD2 . ASP A 1 479 ? 148.452 129.335 134.609 1.00 49.10  -1 468 ASP A OD2 1 
ATOM   3374  N  N   . CYS A 1 480 ? 152.627 130.590 138.107 1.00 48.89  ?  469 CYS A N   1 
ATOM   3375  C  CA  . CYS A 1 480 ? 153.693 130.294 139.048 1.00 48.89  ?  469 CYS A CA  1 
ATOM   3376  C  C   . CYS A 1 480 ? 153.559 131.175 140.282 1.00 48.89  ?  469 CYS A C   1 
ATOM   3377  O  O   . CYS A 1 480 ? 153.780 130.735 141.389 1.00 48.89  ?  469 CYS A O   1 
ATOM   3378  C  CB  . CYS A 1 480 ? 155.059 130.491 138.399 1.00 48.89  ?  469 CYS A CB  1 
ATOM   3379  S  SG  . CYS A 1 480 ? 156.452 130.082 139.459 1.00 48.89  ?  469 CYS A SG  1 
ATOM   3380  N  N   . LEU A 1 481 ? 153.212 132.434 140.065 1.00 45.54  ?  470 LEU A N   1 
ATOM   3381  C  CA  . LEU A 1 481 ? 152.997 133.388 141.125 1.00 45.54  ?  470 LEU A CA  1 
ATOM   3382  C  C   . LEU A 1 481 ? 151.821 132.967 141.982 1.00 45.54  ?  470 LEU A C   1 
ATOM   3383  O  O   . LEU A 1 481 ? 151.840 133.154 143.179 1.00 45.54  ?  470 LEU A O   1 
ATOM   3384  C  CB  . LEU A 1 481 ? 152.774 134.780 140.546 1.00 45.54  ?  470 LEU A CB  1 
ATOM   3385  C  CG  . LEU A 1 481 ? 152.611 135.941 141.523 1.00 45.54  ?  470 LEU A CG  1 
ATOM   3386  C  CD1 . LEU A 1 481 ? 153.857 136.147 142.362 1.00 45.54  ?  470 LEU A CD1 1 
ATOM   3387  C  CD2 . LEU A 1 481 ? 152.227 137.203 140.781 1.00 45.54  ?  470 LEU A CD2 1 
ATOM   3388  N  N   . ILE A 1 482 ? 150.774 132.457 141.348 1.00 44.88  ?  471 ILE A N   1 
ATOM   3389  C  CA  . ILE A 1 482 ? 149.599 131.967 142.039 1.00 44.88  ?  471 ILE A CA  1 
ATOM   3390  C  C   . ILE A 1 482 ? 149.917 130.757 142.898 1.00 44.88  ?  471 ILE A C   1 
ATOM   3391  O  O   . ILE A 1 482 ? 149.411 130.650 143.985 1.00 44.88  ?  471 ILE A O   1 
ATOM   3392  C  CB  . ILE A 1 482 ? 148.461 131.590 141.068 1.00 44.88  ?  471 ILE A CB  1 
ATOM   3393  C  CG1 . ILE A 1 482 ? 147.858 132.828 140.419 1.00 44.88  ?  471 ILE A CG1 1 
ATOM   3394  C  CG2 . ILE A 1 482 ? 147.370 130.810 141.779 1.00 44.88  ?  471 ILE A CG2 1 
ATOM   3395  C  CD1 . ILE A 1 482 ? 146.948 132.494 139.262 1.00 44.88  ?  471 ILE A CD1 1 
ATOM   3396  N  N   . TRP A 1 483 ? 150.725 129.832 142.397 1.00 45.85  ?  472 TRP A N   1 
ATOM   3397  C  CA  . TRP A 1 483 ? 151.077 128.657 143.162 1.00 45.85  ?  472 TRP A CA  1 
ATOM   3398  C  C   . TRP A 1 483 ? 151.854 129.065 144.398 1.00 45.85  ?  472 TRP A C   1 
ATOM   3399  O  O   . TRP A 1 483 ? 151.583 128.596 145.479 1.00 45.85  ?  472 TRP A O   1 
ATOM   3400  C  CB  . TRP A 1 483 ? 151.926 127.709 142.311 1.00 45.85  ?  472 TRP A CB  1 
ATOM   3401  C  CG  . TRP A 1 483 ? 152.132 126.334 142.886 1.00 45.85  ?  472 TRP A CG  1 
ATOM   3402  C  CD1 . TRP A 1 483 ? 151.596 125.186 142.439 1.00 45.85  ?  472 TRP A CD1 1 
ATOM   3403  C  CD2 . TRP A 1 483 ? 152.946 125.981 144.009 1.00 45.85  ?  472 TRP A CD2 1 
ATOM   3404  N  NE1 . TRP A 1 483 ? 152.005 124.137 143.204 1.00 45.85  ?  472 TRP A NE1 1 
ATOM   3405  C  CE2 . TRP A 1 483 ? 152.839 124.598 144.180 1.00 45.85  ?  472 TRP A CE2 1 
ATOM   3406  C  CE3 . TRP A 1 483 ? 153.746 126.705 144.895 1.00 45.85  ?  472 TRP A CE3 1 
ATOM   3407  C  CZ2 . TRP A 1 483 ? 153.502 123.921 145.190 1.00 45.85  ?  472 TRP A CZ2 1 
ATOM   3408  C  CZ3 . TRP A 1 483 ? 154.397 126.033 145.891 1.00 45.85  ?  472 TRP A CZ3 1 
ATOM   3409  C  CH2 . TRP A 1 483 ? 154.272 124.657 146.034 1.00 45.85  ?  472 TRP A CH2 1 
ATOM   3410  N  N   . ILE A 1 484 ? 152.819 129.952 144.225 1.00 46.79  ?  473 ILE A N   1 
ATOM   3411  C  CA  . ILE A 1 484 ? 153.635 130.431 145.326 1.00 46.79  ?  473 ILE A CA  1 
ATOM   3412  C  C   . ILE A 1 484 ? 152.901 131.263 146.366 1.00 46.79  ?  473 ILE A C   1 
ATOM   3413  O  O   . ILE A 1 484 ? 153.095 131.066 147.537 1.00 46.79  ?  473 ILE A O   1 
ATOM   3414  C  CB  . ILE A 1 484 ? 154.879 131.163 144.805 1.00 46.79  ?  473 ILE A CB  1 
ATOM   3415  C  CG1 . ILE A 1 484 ? 155.748 130.183 144.023 1.00 46.79  ?  473 ILE A CG1 1 
ATOM   3416  C  CG2 . ILE A 1 484 ? 155.664 131.768 145.951 1.00 46.79  ?  473 ILE A CG2 1 
ATOM   3417  C  CD1 . ILE A 1 484 ? 156.797 130.830 143.162 1.00 46.79  ?  473 ILE A CD1 1 
ATOM   3418  N  N   . MET A 1 485 ? 152.054 132.188 145.943 1.00 47.59  ?  474 MET A N   1 
ATOM   3419  C  CA  . MET A 1 485 ? 151.313 132.990 146.893 1.00 47.59  ?  474 MET A CA  1 
ATOM   3420  C  C   . MET A 1 485 ? 150.358 132.135 147.675 1.00 47.59  ?  474 MET A C   1 
ATOM   3421  O  O   . MET A 1 485 ? 150.196 132.323 148.855 1.00 47.59  ?  474 MET A O   1 
ATOM   3422  C  CB  . MET A 1 485 ? 150.572 134.136 146.220 1.00 47.59  ?  474 MET A CB  1 
ATOM   3423  C  CG  . MET A 1 485 ? 151.485 135.210 145.675 1.00 47.59  ?  474 MET A CG  1 
ATOM   3424  S  SD  . MET A 1 485 ? 152.972 135.433 146.658 1.00 47.59  ?  474 MET A SD  1 
ATOM   3425  C  CE  . MET A 1 485 ? 152.327 136.188 148.140 1.00 47.59  ?  474 MET A CE  1 
ATOM   3426  N  N   . THR A 1 486 ? 149.715 131.198 146.996 1.00 46.29  ?  475 THR A N   1 
ATOM   3427  C  CA  . THR A 1 486 ? 148.780 130.310 147.640 1.00 46.29  ?  475 THR A CA  1 
ATOM   3428  C  C   . THR A 1 486 ? 149.499 129.474 148.662 1.00 46.29  ?  475 THR A C   1 
ATOM   3429  O  O   . THR A 1 486 ? 149.020 129.300 149.756 1.00 46.29  ?  475 THR A O   1 
ATOM   3430  C  CB  . THR A 1 486 ? 148.103 129.369 146.632 1.00 46.29  ?  475 THR A CB  1 
ATOM   3431  O  OG1 . THR A 1 486 ? 147.474 130.139 145.611 1.00 46.29  ?  475 THR A OG1 1 
ATOM   3432  C  CG2 . THR A 1 486 ? 147.066 128.542 147.309 1.00 46.29  ?  475 THR A CG2 1 
ATOM   3433  N  N   . PHE A 1 487 ? 150.664 128.961 148.307 1.00 45.31  ?  476 PHE A N   1 
ATOM   3434  C  CA  . PHE A 1 487 ? 151.415 128.169 149.241 1.00 45.31  ?  476 PHE A CA  1 
ATOM   3435  C  C   . PHE A 1 487 ? 151.840 128.999 150.443 1.00 45.31  ?  476 PHE A C   1 
ATOM   3436  O  O   . PHE A 1 487 ? 151.710 128.566 151.561 1.00 45.31  ?  476 PHE A O   1 
ATOM   3437  C  CB  . PHE A 1 487 ? 152.629 127.560 148.564 1.00 45.31  ?  476 PHE A CB  1 
ATOM   3438  C  CG  . PHE A 1 487 ? 153.419 126.667 149.453 1.00 45.31  ?  476 PHE A CG  1 
ATOM   3439  C  CD1 . PHE A 1 487 ? 153.133 125.328 149.530 1.00 45.31  ?  476 PHE A CD1 1 
ATOM   3440  C  CD2 . PHE A 1 487 ? 154.442 127.172 150.225 1.00 45.31  ?  476 PHE A CD2 1 
ATOM   3441  C  CE1 . PHE A 1 487 ? 153.851 124.504 150.356 1.00 45.31  ?  476 PHE A CE1 1 
ATOM   3442  C  CE2 . PHE A 1 487 ? 155.166 126.355 151.057 1.00 45.31  ?  476 PHE A CE2 1 
ATOM   3443  C  CZ  . PHE A 1 487 ? 154.869 125.016 151.120 1.00 45.31  ?  476 PHE A CZ  1 
ATOM   3444  N  N   . ILE A 1 488 ? 152.328 130.207 150.211 1.00 45.98  ?  477 ILE A N   1 
ATOM   3445  C  CA  . ILE A 1 488 ? 152.743 131.064 151.306 1.00 45.98  ?  477 ILE A CA  1 
ATOM   3446  C  C   . ILE A 1 488 ? 151.572 131.461 152.198 1.00 45.98  ?  477 ILE A C   1 
ATOM   3447  O  O   . ILE A 1 488 ? 151.690 131.434 153.398 1.00 45.98  ?  477 ILE A O   1 
ATOM   3448  C  CB  . ILE A 1 488 ? 153.480 132.330 150.813 1.00 45.98  ?  477 ILE A CB  1 
ATOM   3449  C  CG1 . ILE A 1 488 ? 154.795 131.969 150.134 1.00 45.98  ?  477 ILE A CG1 1 
ATOM   3450  C  CG2 . ILE A 1 488 ? 153.755 133.274 151.965 1.00 45.98  ?  477 ILE A CG2 1 
ATOM   3451  C  CD1 . ILE A 1 488 ? 155.374 133.090 149.306 1.00 45.98  ?  477 ILE A CD1 1 
ATOM   3452  N  N   . PHE A 1 489 ? 150.442 131.813 151.602 1.00 46.92  ?  478 PHE A N   1 
ATOM   3453  C  CA  . PHE A 1 489 ? 149.258 132.218 152.350 1.00 46.92  ?  478 PHE A CA  1 
ATOM   3454  C  C   . PHE A 1 489 ? 148.712 131.095 153.201 1.00 46.92  ?  478 PHE A C   1 
ATOM   3455  O  O   . PHE A 1 489 ? 148.225 131.327 154.273 1.00 46.92  ?  478 PHE A O   1 
ATOM   3456  C  CB  . PHE A 1 489 ? 148.147 132.717 151.434 1.00 46.92  ?  478 PHE A CB  1 
ATOM   3457  C  CG  . PHE A 1 489 ? 148.373 134.085 150.889 1.00 46.92  ?  478 PHE A CG  1 
ATOM   3458  C  CD1 . PHE A 1 489 ? 149.053 135.034 151.626 1.00 46.92  ?  478 PHE A CD1 1 
ATOM   3459  C  CD2 . PHE A 1 489 ? 147.894 134.429 149.639 1.00 46.92  ?  478 PHE A CD2 1 
ATOM   3460  C  CE1 . PHE A 1 489 ? 149.256 136.297 151.118 1.00 46.92  ?  478 PHE A CE1 1 
ATOM   3461  C  CE2 . PHE A 1 489 ? 148.093 135.686 149.126 1.00 46.92  ?  478 PHE A CE2 1 
ATOM   3462  C  CZ  . PHE A 1 489 ? 148.771 136.623 149.867 1.00 46.92  ?  478 PHE A CZ  1 
ATOM   3463  N  N   . THR A 1 490 ? 148.711 129.889 152.659 1.00 47.12  ?  479 THR A N   1 
ATOM   3464  C  CA  . THR A 1 490 ? 148.260 128.698 153.355 1.00 47.12  ?  479 THR A CA  1 
ATOM   3465  C  C   . THR A 1 490 ? 149.171 128.337 154.522 1.00 47.12  ?  479 THR A C   1 
ATOM   3466  O  O   . THR A 1 490 ? 148.763 127.611 155.397 1.00 47.12  ?  479 THR A O   1 
ATOM   3467  C  CB  . THR A 1 490 ? 148.028 127.518 152.400 1.00 47.12  ?  479 THR A CB  1 
ATOM   3468  O  OG1 . THR A 1 490 ? 147.258 127.973 151.291 1.00 47.12  ?  479 THR A OG1 1 
ATOM   3469  C  CG2 . THR A 1 490 ? 147.269 126.422 153.088 1.00 47.12  ?  479 THR A CG2 1 
ATOM   3470  N  N   . ILE A 1 491 ? 150.461 128.576 154.374 1.00 47.11  ?  480 ILE A N   1 
ATOM   3471  C  CA  . ILE A 1 491 ? 151.413 128.386 155.463 1.00 47.11  ?  480 ILE A CA  1 
ATOM   3472  C  C   . ILE A 1 491 ? 151.429 129.417 156.618 1.00 47.11  ?  480 ILE A C   1 
ATOM   3473  O  O   . ILE A 1 491 ? 151.460 129.034 157.769 1.00 47.11  ?  480 ILE A O   1 
ATOM   3474  C  CB  . ILE A 1 491 ? 152.845 128.173 154.934 1.00 47.11  ?  480 ILE A CB  1 
ATOM   3475  C  CG1 . ILE A 1 491 ? 152.922 126.928 154.047 1.00 47.11  ?  480 ILE A CG1 1 
ATOM   3476  C  CG2 . ILE A 1 491 ? 153.824 128.076 156.084 1.00 47.11  ?  480 ILE A CG2 1 
ATOM   3477  C  CD1 . ILE A 1 491 ? 152.843 125.619 154.785 1.00 47.11  ?  480 ILE A CD1 1 
ATOM   3478  N  N   . VAL A 1 492 ? 151.362 130.712 156.296 1.00 49.53  ?  481 VAL A N   1 
ATOM   3479  C  CA  . VAL A 1 492 ? 151.472 131.823 157.268 1.00 49.53  ?  481 VAL A CA  1 
ATOM   3480  C  C   . VAL A 1 492 ? 150.172 132.121 157.975 1.00 49.53  ?  481 VAL A C   1 
ATOM   3481  O  O   . VAL A 1 492 ? 150.094 132.180 159.184 1.00 49.53  ?  481 VAL A O   1 
ATOM   3482  C  CB  . VAL A 1 492 ? 152.029 133.073 156.602 1.00 49.53  ?  481 VAL A CB  1 
ATOM   3483  C  CG1 . VAL A 1 492 ? 151.961 134.243 157.559 1.00 49.53  ?  481 VAL A CG1 1 
ATOM   3484  C  CG2 . VAL A 1 492 ? 153.455 132.802 156.174 1.00 49.53  ?  481 VAL A CG2 1 
ATOM   3485  N  N   . LEU A 1 493 ? 149.116 132.226 157.168 1.00 50.82  ?  482 LEU A N   1 
ATOM   3486  C  CA  . LEU A 1 493 ? 147.755 132.300 157.636 1.00 50.82  ?  482 LEU A CA  1 
ATOM   3487  C  C   . LEU A 1 493 ? 147.332 130.864 157.578 1.00 50.82  ?  482 LEU A C   1 
ATOM   3488  O  O   . LEU A 1 493 ? 148.038 130.036 157.011 1.00 50.82  ?  482 LEU A O   1 
ATOM   3489  C  CB  . LEU A 1 493 ? 146.900 133.144 156.712 1.00 50.82  ?  482 LEU A CB  1 
ATOM   3490  C  CG  . LEU A 1 493 ? 147.463 134.501 156.309 1.00 50.82  ?  482 LEU A CG  1 
ATOM   3491  C  CD1 . LEU A 1 493 ? 146.588 135.144 155.245 1.00 50.82  ?  482 LEU A CD1 1 
ATOM   3492  C  CD2 . LEU A 1 493 ? 147.593 135.396 157.529 1.00 50.82  ?  482 LEU A CD2 1 
ATOM   3493  N  N   . GLY A 1 494 ? 146.203 130.517 158.154 1.00 52.86  ?  483 GLY A N   1 
ATOM   3494  C  CA  . GLY A 1 494 ? 145.858 129.114 158.161 1.00 52.86  ?  483 GLY A CA  1 
ATOM   3495  C  C   . GLY A 1 494 ? 145.316 128.582 156.861 1.00 52.86  ?  483 GLY A C   1 
ATOM   3496  O  O   . GLY A 1 494 ? 145.348 129.264 155.846 1.00 52.86  ?  483 GLY A O   1 
ATOM   3497  N  N   . LEU A 1 495 ? 144.818 127.356 156.885 1.00 51.45  ?  484 LEU A N   1 
ATOM   3498  C  CA  . LEU A 1 495 ? 144.223 126.767 155.702 1.00 51.45  ?  484 LEU A CA  1 
ATOM   3499  C  C   . LEU A 1 495 ? 143.005 127.561 155.258 1.00 51.45  ?  484 LEU A C   1 
ATOM   3500  O  O   . LEU A 1 495 ? 142.820 127.797 154.068 1.00 51.45  ?  484 LEU A O   1 
ATOM   3501  C  CB  . LEU A 1 495 ? 143.826 125.322 155.993 1.00 51.45  ?  484 LEU A CB  1 
ATOM   3502  C  CG  . LEU A 1 495 ? 144.906 124.400 156.558 1.00 51.45  ?  484 LEU A CG  1 
ATOM   3503  C  CD1 . LEU A 1 495 ? 144.286 123.172 157.204 1.00 51.45  ?  484 LEU A CD1 1 
ATOM   3504  C  CD2 . LEU A 1 495 ? 145.894 124.005 155.474 1.00 51.45  ?  484 LEU A CD2 1 
ATOM   3505  N  N   . GLY A 1 496 ? 142.172 127.976 156.203 1.00 52.21  ?  485 GLY A N   1 
ATOM   3506  C  CA  . GLY A 1 496 ? 140.971 128.718 155.866 1.00 52.21  ?  485 GLY A CA  1 
ATOM   3507  C  C   . GLY A 1 496 ? 141.190 130.155 155.461 1.00 52.21  ?  485 GLY A C   1 
ATOM   3508  O  O   . GLY A 1 496 ? 140.753 130.566 154.392 1.00 52.21  ?  485 GLY A O   1 
ATOM   3509  N  N   . LEU A 1 497 ? 141.862 130.930 156.302 1.00 53.32  ?  486 LEU A N   1 
ATOM   3510  C  CA  . LEU A 1 497 ? 142.161 132.317 155.967 1.00 53.32  ?  486 LEU A CA  1 
ATOM   3511  C  C   . LEU A 1 497 ? 143.119 132.384 154.800 1.00 53.32  ?  486 LEU A C   1 
ATOM   3512  O  O   . LEU A 1 497 ? 143.014 133.272 153.961 1.00 53.32  ?  486 LEU A O   1 
ATOM   3513  C  CB  . LEU A 1 497 ? 142.745 133.054 157.167 1.00 53.32  ?  486 LEU A CB  1 
ATOM   3514  C  CG  . LEU A 1 497 ? 141.841 134.106 157.803 1.00 53.32  ?  486 LEU A CG  1 
ATOM   3515  C  CD1 . LEU A 1 497 ? 142.571 134.791 158.946 1.00 53.32  ?  486 LEU A CD1 1 
ATOM   3516  C  CD2 . LEU A 1 497 ? 141.411 135.121 156.757 1.00 53.32  ?  486 LEU A CD2 1 
ATOM   3517  N  N   . GLY A 1 498 ? 144.058 131.452 154.742 1.00 49.44  ?  487 GLY A N   1 
ATOM   3518  C  CA  . GLY A 1 498 ? 144.980 131.412 153.632 1.00 49.44  ?  487 GLY A CA  1 
ATOM   3519  C  C   . GLY A 1 498 ? 144.263 131.196 152.326 1.00 49.44  ?  487 GLY A C   1 
ATOM   3520  O  O   . GLY A 1 498 ? 144.635 131.778 151.318 1.00 49.44  ?  487 GLY A O   1 
ATOM   3521  N  N   . LEU A 1 499 ? 143.230 130.366 152.337 1.00 47.37  ?  488 LEU A N   1 
ATOM   3522  C  CA  . LEU A 1 499 ? 142.458 130.117 151.132 1.00 47.37  ?  488 LEU A CA  1 
ATOM   3523  C  C   . LEU A 1 499 ? 141.737 131.368 150.665 1.00 47.37  ?  488 LEU A C   1 
ATOM   3524  O  O   . LEU A 1 499 ? 141.768 131.690 149.484 1.00 47.37  ?  488 LEU A O   1 
ATOM   3525  C  CB  . LEU A 1 499 ? 141.447 128.994 151.355 1.00 47.37  ?  488 LEU A CB  1 
ATOM   3526  C  CG  . LEU A 1 499 ? 140.659 128.571 150.117 1.00 47.37  ?  488 LEU A CG  1 
ATOM   3527  C  CD1 . LEU A 1 499 ? 141.596 128.036 149.045 1.00 47.37  ?  488 LEU A CD1 1 
ATOM   3528  C  CD2 . LEU A 1 499 ? 139.615 127.532 150.486 1.00 47.37  ?  488 LEU A CD2 1 
ATOM   3529  N  N   . ALA A 1 500 ? 141.089 132.078 151.580 1.00 45.32  ?  489 ALA A N   1 
ATOM   3530  C  CA  . ALA A 1 500 ? 140.440 133.326 151.198 1.00 45.32  ?  489 ALA A CA  1 
ATOM   3531  C  C   . ALA A 1 500 ? 141.440 134.313 150.612 1.00 45.32  ?  489 ALA A C   1 
ATOM   3532  O  O   . ALA A 1 500 ? 141.190 134.910 149.555 1.00 45.32  ?  489 ALA A O   1 
ATOM   3533  C  CB  . ALA A 1 500 ? 139.729 133.930 152.405 1.00 45.32  ?  489 ALA A CB  1 
ATOM   3534  N  N   . ALA A 1 501 ? 142.581 134.491 151.279 1.00 45.01  ?  490 ALA A N   1 
ATOM   3535  C  CA  . ALA A 1 501 ? 143.607 135.382 150.751 1.00 45.01  ?  490 ALA A CA  1 
ATOM   3536  C  C   . ALA A 1 501 ? 144.111 134.904 149.396 1.00 45.01  ?  490 ALA A C   1 
ATOM   3537  O  O   . ALA A 1 501 ? 144.402 135.716 148.512 1.00 45.01  ?  490 ALA A O   1 
ATOM   3538  C  CB  . ALA A 1 501 ? 144.760 135.499 151.742 1.00 45.01  ?  490 ALA A CB  1 
ATOM   3539  N  N   . SER A 1 502 ? 144.194 133.588 149.202 1.00 45.36  ?  491 SER A N   1 
ATOM   3540  C  CA  . SER A 1 502 ? 144.700 133.051 147.948 1.00 45.36  ?  491 SER A CA  1 
ATOM   3541  C  C   . SER A 1 502 ? 143.716 133.270 146.811 1.00 45.36  ?  491 SER A C   1 
ATOM   3542  O  O   . SER A 1 502 ? 144.120 133.574 145.687 1.00 45.36  ?  491 SER A O   1 
ATOM   3543  C  CB  . SER A 1 502 ? 144.999 131.571 148.116 1.00 45.36  ?  491 SER A CB  1 
ATOM   3544  O  OG  . SER A 1 502 ? 145.904 131.375 149.179 1.00 45.36  ?  491 SER A OG  1 
ATOM   3545  N  N   . VAL A 1 503 ? 142.422 133.114 147.081 1.00 43.79  ?  492 VAL A N   1 
ATOM   3546  C  CA  . VAL A 1 503 ? 141.419 133.374 146.056 1.00 43.79  ?  492 VAL A CA  1 
ATOM   3547  C  C   . VAL A 1 503 ? 141.420 134.848 145.677 1.00 43.79  ?  492 VAL A C   1 
ATOM   3548  O  O   . VAL A 1 503 ? 141.324 135.201 144.495 1.00 43.79  ?  492 VAL A O   1 
ATOM   3549  C  CB  . VAL A 1 503 ? 140.034 132.904 146.533 1.00 43.79  ?  492 VAL A CB  1 
ATOM   3550  C  CG1 . VAL A 1 503 ? 138.977 133.276 145.529 1.00 43.79  ?  492 VAL A CG1 1 
ATOM   3551  C  CG2 . VAL A 1 503 ? 140.036 131.416 146.750 1.00 43.79  ?  492 VAL A CG2 1 
ATOM   3552  N  N   . ALA A 1 504 ? 141.560 135.731 146.667 1.00 42.65  ?  493 ALA A N   1 
ATOM   3553  C  CA  . ALA A 1 504 ? 141.646 137.156 146.363 1.00 42.65  ?  493 ALA A CA  1 
ATOM   3554  C  C   . ALA A 1 504 ? 142.869 137.475 145.509 1.00 42.65  ?  493 ALA A C   1 
ATOM   3555  O  O   . ALA A 1 504 ? 142.778 138.228 144.531 1.00 42.65  ?  493 ALA A O   1 
ATOM   3556  C  CB  . ALA A 1 504 ? 141.669 137.966 147.656 1.00 42.65  ?  493 ALA A CB  1 
ATOM   3557  N  N   . PHE A 1 505 ? 144.026 136.911 145.857 1.00 43.54  ?  494 PHE A N   1 
ATOM   3558  C  CA  . PHE A 1 505 ? 145.224 137.186 145.076 1.00 43.54  ?  494 PHE A CA  1 
ATOM   3559  C  C   . PHE A 1 505 ? 145.129 136.610 143.670 1.00 43.54  ?  494 PHE A C   1 
ATOM   3560  O  O   . PHE A 1 505 ? 145.634 137.209 142.713 1.00 43.54  ?  494 PHE A O   1 
ATOM   3561  C  CB  . PHE A 1 505 ? 146.455 136.636 145.784 1.00 43.54  ?  494 PHE A CB  1 
ATOM   3562  C  CG  . PHE A 1 505 ? 147.725 136.928 145.065 1.00 43.54  ?  494 PHE A CG  1 
ATOM   3563  C  CD1 . PHE A 1 505 ? 148.305 135.984 144.246 1.00 43.54  ?  494 PHE A CD1 1 
ATOM   3564  C  CD2 . PHE A 1 505 ? 148.328 138.161 145.185 1.00 43.54  ?  494 PHE A CD2 1 
ATOM   3565  C  CE1 . PHE A 1 505 ? 149.459 136.263 143.574 1.00 43.54  ?  494 PHE A CE1 1 
ATOM   3566  C  CE2 . PHE A 1 505 ? 149.483 138.439 144.517 1.00 43.54  ?  494 PHE A CE2 1 
ATOM   3567  C  CZ  . PHE A 1 505 ? 150.050 137.492 143.713 1.00 43.54  ?  494 PHE A CZ  1 
ATOM   3568  N  N   . GLN A 1 506 ? 144.494 135.454 143.523 1.00 43.50  ?  495 GLN A N   1 
ATOM   3569  C  CA  . GLN A 1 506 ? 144.338 134.867 142.204 1.00 43.50  ?  495 GLN A CA  1 
ATOM   3570  C  C   . GLN A 1 506 ? 143.405 135.704 141.340 1.00 43.50  ?  495 GLN A C   1 
ATOM   3571  O  O   . GLN A 1 506 ? 143.592 135.790 140.124 1.00 43.50  ?  495 GLN A O   1 
ATOM   3572  C  CB  . GLN A 1 506 ? 143.844 133.435 142.353 1.00 43.50  ?  495 GLN A CB  1 
ATOM   3573  C  CG  . GLN A 1 506 ? 143.116 132.878 141.183 1.00 43.50  ?  495 GLN A CG  1 
ATOM   3574  C  CD  . GLN A 1 506 ? 142.047 131.926 141.613 1.00 43.50  ?  495 GLN A CD  1 
ATOM   3575  O  OE1 . GLN A 1 506 ? 141.037 132.328 142.172 1.00 43.50  ?  495 GLN A OE1 1 
ATOM   3576  N  NE2 . GLN A 1 506 ? 142.263 130.654 141.368 1.00 43.50  ?  495 GLN A NE2 1 
ATOM   3577  N  N   . LEU A 1 507 ? 142.408 136.347 141.950 1.00 43.81  ?  496 LEU A N   1 
ATOM   3578  C  CA  . LEU A 1 507 ? 141.608 137.315 141.206 1.00 43.81  ?  496 LEU A CA  1 
ATOM   3579  C  C   . LEU A 1 507 ? 142.432 138.533 140.816 1.00 43.81  ?  496 LEU A C   1 
ATOM   3580  O  O   . LEU A 1 507 ? 142.239 139.098 139.738 1.00 43.81  ?  496 LEU A O   1 
ATOM   3581  C  CB  . LEU A 1 507 ? 140.397 137.753 142.021 1.00 43.81  ?  496 LEU A CB  1 
ATOM   3582  C  CG  . LEU A 1 507 ? 139.349 136.711 142.371 1.00 43.81  ?  496 LEU A CG  1 
ATOM   3583  C  CD1 . LEU A 1 507 ? 138.199 137.386 143.067 1.00 43.81  ?  496 LEU A CD1 1 
ATOM   3584  C  CD2 . LEU A 1 507 ? 138.884 135.975 141.142 1.00 43.81  ?  496 LEU A CD2 1 
ATOM   3585  N  N   . LEU A 1 508 ? 143.336 138.965 141.689 1.00 42.58  ?  497 LEU A N   1 
ATOM   3586  C  CA  . LEU A 1 508 ? 144.181 140.112 141.371 1.00 42.58  ?  497 LEU A CA  1 
ATOM   3587  C  C   . LEU A 1 508 ? 145.140 139.818 140.219 1.00 42.58  ?  497 LEU A C   1 
ATOM   3588  O  O   . LEU A 1 508 ? 145.520 140.729 139.478 1.00 42.58  ?  497 LEU A O   1 
ATOM   3589  C  CB  . LEU A 1 508 ? 144.949 140.537 142.618 1.00 42.58  ?  497 LEU A CB  1 
ATOM   3590  C  CG  . LEU A 1 508 ? 145.833 141.774 142.574 1.00 42.58  ?  497 LEU A CG  1 
ATOM   3591  C  CD1 . LEU A 1 508 ? 145.010 143.018 142.347 1.00 42.58  ?  497 LEU A CD1 1 
ATOM   3592  C  CD2 . LEU A 1 508 ? 146.603 141.880 143.861 1.00 42.58  ?  497 LEU A CD2 1 
ATOM   3593  N  N   . THR A 1 509 ? 145.558 138.565 140.062 1.00 43.18  ?  498 THR A N   1 
ATOM   3594  C  CA  . THR A 1 509 ? 146.444 138.230 138.948 1.00 43.18  ?  498 THR A CA  1 
ATOM   3595  C  C   . THR A 1 509 ? 145.769 138.396 137.592 1.00 43.18  ?  498 THR A C   1 
ATOM   3596  O  O   . THR A 1 509 ? 146.458 138.610 136.592 1.00 43.18  ?  498 THR A O   1 
ATOM   3597  C  CB  . THR A 1 509 ? 146.965 136.804 139.074 1.00 43.18  ?  498 THR A CB  1 
ATOM   3598  O  OG1 . THR A 1 509 ? 145.860 135.899 139.162 1.00 43.18  ?  498 THR A OG1 1 
ATOM   3599  C  CG2 . THR A 1 509 ? 147.841 136.665 140.287 1.00 43.18  ?  498 THR A CG2 1 
ATOM   3600  N  N   . ILE A 1 510 ? 144.441 138.283 137.529 1.00 44.11  ?  499 ILE A N   1 
ATOM   3601  C  CA  . ILE A 1 510 ? 143.736 138.544 136.279 1.00 44.11  ?  499 ILE A CA  1 
ATOM   3602  C  C   . ILE A 1 510 ? 143.925 139.994 135.865 1.00 44.11  ?  499 ILE A C   1 
ATOM   3603  O  O   . ILE A 1 510 ? 144.085 140.303 134.681 1.00 44.11  ?  499 ILE A O   1 
ATOM   3604  C  CB  . ILE A 1 510 ? 142.245 138.190 136.414 1.00 44.11  ?  499 ILE A CB  1 
ATOM   3605  C  CG1 . ILE A 1 510 ? 142.061 136.706 136.719 1.00 44.11  ?  499 ILE A CG1 1 
ATOM   3606  C  CG2 . ILE A 1 510 ? 141.500 138.548 135.151 1.00 44.11  ?  499 ILE A CG2 1 
ATOM   3607  C  CD1 . ILE A 1 510 ? 142.521 135.803 135.613 1.00 44.11  ?  499 ILE A CD1 1 
ATOM   3608  N  N   . VAL A 1 511 ? 143.910 140.905 136.834 1.00 42.86  ?  500 VAL A N   1 
ATOM   3609  C  CA  . VAL A 1 511 ? 144.205 142.300 136.545 1.00 42.86  ?  500 VAL A CA  1 
ATOM   3610  C  C   . VAL A 1 511 ? 145.672 142.468 136.189 1.00 42.86  ?  500 VAL A C   1 
ATOM   3611  O  O   . VAL A 1 511 ? 146.017 143.226 135.281 1.00 42.86  ?  500 VAL A O   1 
ATOM   3612  C  CB  . VAL A 1 511 ? 143.799 143.186 137.735 1.00 42.86  ?  500 VAL A CB  1 
ATOM   3613  C  CG1 . VAL A 1 511 ? 144.217 144.612 137.498 1.00 42.86  ?  500 VAL A CG1 1 
ATOM   3614  C  CG2 . VAL A 1 511 ? 142.319 143.111 137.946 1.00 42.86  ?  500 VAL A CG2 1 
ATOM   3615  N  N   . PHE A 1 512 ? 146.558 141.758 136.889 1.00 42.70  ?  501 PHE A N   1 
ATOM   3616  C  CA  . PHE A 1 512 ? 147.978 141.803 136.545 1.00 42.70  ?  501 PHE A CA  1 
ATOM   3617  C  C   . PHE A 1 512 ? 148.210 141.441 135.084 1.00 42.70  ?  501 PHE A C   1 
ATOM   3618  O  O   . PHE A 1 512 ? 149.089 142.009 134.431 1.00 42.70  ?  501 PHE A O   1 
ATOM   3619  C  CB  . PHE A 1 512 ? 148.784 140.858 137.432 1.00 42.70  ?  501 PHE A CB  1 
ATOM   3620  C  CG  . PHE A 1 512 ? 148.954 141.330 138.833 1.00 42.70  ?  501 PHE A CG  1 
ATOM   3621  C  CD1 . PHE A 1 512 ? 148.602 142.607 139.198 1.00 42.70  ?  501 PHE A CD1 1 
ATOM   3622  C  CD2 . PHE A 1 512 ? 149.466 140.484 139.793 1.00 42.70  ?  501 PHE A CD2 1 
ATOM   3623  C  CE1 . PHE A 1 512 ? 148.755 143.029 140.488 1.00 42.70  ?  501 PHE A CE1 1 
ATOM   3624  C  CE2 . PHE A 1 512 ? 149.620 140.903 141.081 1.00 42.70  ?  501 PHE A CE2 1 
ATOM   3625  C  CZ  . PHE A 1 512 ? 149.266 142.176 141.429 1.00 42.70  ?  501 PHE A CZ  1 
ATOM   3626  N  N   . ARG A 1 513 ? 147.437 140.491 134.558 1.00 44.67  ?  502 ARG A N   1 
ATOM   3627  C  CA  . ARG A 1 513 ? 147.617 140.045 133.180 1.00 44.67  ?  502 ARG A CA  1 
ATOM   3628  C  C   . ARG A 1 513 ? 147.238 141.126 132.180 1.00 44.67  ?  502 ARG A C   1 
ATOM   3629  O  O   . ARG A 1 513 ? 147.865 141.253 131.125 1.00 44.67  ?  502 ARG A O   1 
ATOM   3630  C  CB  . ARG A 1 513 ? 146.781 138.799 132.919 1.00 44.67  ?  502 ARG A CB  1 
ATOM   3631  C  CG  . ARG A 1 513 ? 147.319 137.546 133.509 1.00 44.67  ?  502 ARG A CG  1 
ATOM   3632  C  CD  . ARG A 1 513 ? 146.388 136.415 133.208 1.00 44.67  ?  502 ARG A CD  1 
ATOM   3633  N  NE  . ARG A 1 513 ? 146.763 135.199 133.910 1.00 44.67  ?  502 ARG A NE  1 
ATOM   3634  C  CZ  . ARG A 1 513 ? 147.584 134.283 133.421 1.00 44.67  ?  502 ARG A CZ  1 
ATOM   3635  N  NH1 . ARG A 1 513 ? 147.867 133.206 134.131 1.00 44.67  1  502 ARG A NH1 1 
ATOM   3636  N  NH2 . ARG A 1 513 ? 148.122 134.444 132.225 1.00 44.67  ?  502 ARG A NH2 1 
ATOM   3637  N  N   . THR A 1 514 ? 146.193 141.891 132.473 1.00 43.99  ?  503 THR A N   1 
ATOM   3638  C  CA  . THR A 1 514 ? 145.605 142.815 131.518 1.00 43.99  ?  503 THR A CA  1 
ATOM   3639  C  C   . THR A 1 514 ? 145.906 144.266 131.839 1.00 43.99  ?  503 THR A C   1 
ATOM   3640  O  O   . THR A 1 514 ? 145.330 145.158 131.221 1.00 43.99  ?  503 THR A O   1 
ATOM   3641  C  CB  . THR A 1 514 ? 144.096 142.599 131.455 1.00 43.99  ?  503 THR A CB  1 
ATOM   3642  O  OG1 . THR A 1 514 ? 143.544 142.733 132.765 1.00 43.99  ?  503 THR A OG1 1 
ATOM   3643  C  CG2 . THR A 1 514 ? 143.790 141.226 130.946 1.00 43.99  ?  503 THR A CG2 1 
ATOM   3644  N  N   . GLN A 1 515 ? 146.812 144.513 132.772 1.00 44.27  ?  504 GLN A N   1 
ATOM   3645  C  CA  . GLN A 1 515 ? 147.107 145.814 133.353 1.00 44.27  ?  504 GLN A CA  1 
ATOM   3646  C  C   . GLN A 1 515 ? 147.922 146.698 132.419 1.00 44.27  ?  504 GLN A C   1 
ATOM   3647  O  O   . GLN A 1 515 ? 147.624 147.882 132.259 1.00 44.27  ?  504 GLN A O   1 
ATOM   3648  C  CB  . GLN A 1 515 ? 147.864 145.584 134.653 1.00 44.27  ?  504 GLN A CB  1 
ATOM   3649  C  CG  . GLN A 1 515 ? 147.875 146.672 135.646 1.00 44.27  ?  504 GLN A CG  1 
ATOM   3650  C  CD  . GLN A 1 515 ? 148.726 146.276 136.810 1.00 44.27  ?  504 GLN A CD  1 
ATOM   3651  O  OE1 . GLN A 1 515 ? 149.443 145.291 136.739 1.00 44.27  ?  504 GLN A OE1 1 
ATOM   3652  N  NE2 . GLN A 1 515 ? 148.663 147.031 137.885 1.00 44.27  ?  504 GLN A NE2 1 
ATOM   3653  N  N   . PHE A 1 516 ? 148.964 146.135 131.810 1.00 43.26  ?  505 PHE A N   1 
ATOM   3654  C  CA  . PHE A 1 516 ? 149.855 146.846 130.900 1.00 43.26  ?  505 PHE A CA  1 
ATOM   3655  C  C   . PHE A 1 516 ? 149.857 146.108 129.570 1.00 43.26  ?  505 PHE A C   1 
ATOM   3656  O  O   . PHE A 1 516 ? 150.839 145.434 129.231 1.00 43.26  ?  505 PHE A O   1 
ATOM   3657  C  CB  . PHE A 1 516 ? 151.271 146.938 131.460 1.00 43.26  ?  505 PHE A CB  1 
ATOM   3658  C  CG  . PHE A 1 516 ? 151.346 147.514 132.838 1.00 43.26  ?  505 PHE A CG  1 
ATOM   3659  C  CD1 . PHE A 1 516 ? 150.680 148.679 133.155 1.00 43.26  ?  505 PHE A CD1 1 
ATOM   3660  C  CD2 . PHE A 1 516 ? 152.089 146.893 133.818 1.00 43.26  ?  505 PHE A CD2 1 
ATOM   3661  C  CE1 . PHE A 1 516 ? 150.749 149.207 134.418 1.00 43.26  ?  505 PHE A CE1 1 
ATOM   3662  C  CE2 . PHE A 1 516 ? 152.163 147.422 135.082 1.00 43.26  ?  505 PHE A CE2 1 
ATOM   3663  C  CZ  . PHE A 1 516 ? 151.492 148.579 135.382 1.00 43.26  ?  505 PHE A CZ  1 
ATOM   3664  N  N   . PRO A 1 517 ? 148.787 146.216 128.788 1.00 45.07  ?  506 PRO A N   1 
ATOM   3665  C  CA  . PRO A 1 517 ? 148.716 145.470 127.529 1.00 45.07  ?  506 PRO A CA  1 
ATOM   3666  C  C   . PRO A 1 517 ? 149.826 145.869 126.572 1.00 45.07  ?  506 PRO A C   1 
ATOM   3667  O  O   . PRO A 1 517 ? 150.218 147.032 126.495 1.00 45.07  ?  506 PRO A O   1 
ATOM   3668  C  CB  . PRO A 1 517 ? 147.341 145.849 126.971 1.00 45.07  ?  506 PRO A CB  1 
ATOM   3669  C  CG  . PRO A 1 517 ? 146.616 146.446 128.092 1.00 45.07  ?  506 PRO A CG  1 
ATOM   3670  C  CD  . PRO A 1 517 ? 147.608 147.067 128.981 1.00 45.07  ?  506 PRO A CD  1 
ATOM   3671  N  N   . LYS A 1 518 ? 150.302 144.913 125.794 1.00 48.91  ?  507 LYS A N   1 
ATOM   3672  C  CA  . LYS A 1 518 ? 151.338 145.208 124.824 1.00 48.91  ?  507 LYS A CA  1 
ATOM   3673  C  C   . LYS A 1 518 ? 150.715 145.805 123.583 1.00 48.91  ?  507 LYS A C   1 
ATOM   3674  O  O   . LYS A 1 518 ? 150.548 145.124 122.582 1.00 48.91  ?  507 LYS A O   1 
ATOM   3675  C  CB  . LYS A 1 518 ? 152.132 143.951 124.492 1.00 48.91  ?  507 LYS A CB  1 
ATOM   3676  C  CG  . LYS A 1 518 ? 152.748 143.267 125.703 1.00 48.91  ?  507 LYS A CG  1 
ATOM   3677  C  CD  . LYS A 1 518 ? 151.746 142.366 126.410 1.00 48.91  ?  507 LYS A CD  1 
ATOM   3678  C  CE  . LYS A 1 518 ? 152.268 141.896 127.758 1.00 48.91  ?  507 LYS A CE  1 
ATOM   3679  N  NZ  . LYS A 1 518 ? 152.381 143.018 128.731 1.00 48.91  1  507 LYS A NZ  1 
ATOM   3680  N  N   . CYS A 1 519 ? 150.369 147.082 123.651 1.00 47.53  ?  508 CYS A N   1 
ATOM   3681  C  CA  . CYS A 1 519 ? 149.738 147.762 122.529 1.00 47.53  ?  508 CYS A CA  1 
ATOM   3682  C  C   . CYS A 1 519 ? 150.682 147.900 121.353 1.00 47.53  ?  508 CYS A C   1 
ATOM   3683  O  O   . CYS A 1 519 ? 151.896 147.894 121.523 1.00 47.53  ?  508 CYS A O   1 
ATOM   3684  C  CB  . CYS A 1 519 ? 149.234 149.130 122.974 1.00 47.53  ?  508 CYS A CB  1 
ATOM   3685  S  SG  . CYS A 1 519 ? 148.037 149.075 124.325 1.00 47.53  ?  508 CYS A SG  1 
ATOM   3686  N  N   . SER A 1 520 ? 150.132 148.020 120.154 1.00 42.72  ?  509 SER A N   1 
ATOM   3687  C  CA  . SER A 1 520 ? 150.982 148.058 118.973 1.00 42.72  ?  509 SER A CA  1 
ATOM   3688  C  C   . SER A 1 520 ? 150.455 148.891 117.835 1.00 42.72  ?  509 SER A C   1 
ATOM   3689  O  O   . SER A 1 520 ? 149.266 149.171 117.758 1.00 42.72  ?  509 SER A O   1 
ATOM   3690  C  CB  . SER A 1 520 ? 151.199 146.630 118.460 1.00 42.72  ?  509 SER A CB  1 
ATOM   3691  O  OG  . SER A 1 520 ? 149.967 145.991 118.190 1.00 42.72  ?  509 SER A OG  1 
ATOM   3692  N  N   . THR A 1 521 ? 151.345 149.285 116.943 1.00 41.82  ?  510 THR A N   1 
ATOM   3693  C  CA  . THR A 1 521 ? 150.942 150.012 115.763 1.00 41.82  ?  510 THR A CA  1 
ATOM   3694  C  C   . THR A 1 521 ? 151.049 148.998 114.657 1.00 41.82  ?  510 THR A C   1 
ATOM   3695  O  O   . THR A 1 521 ? 152.036 148.279 114.575 1.00 41.82  ?  510 THR A O   1 
ATOM   3696  C  CB  . THR A 1 521 ? 151.857 151.209 115.486 1.00 41.82  ?  510 THR A CB  1 
ATOM   3697  O  OG1 . THR A 1 521 ? 151.827 152.100 116.606 1.00 41.82  ?  510 THR A OG1 1 
ATOM   3698  C  CG2 . THR A 1 521 ? 151.400 151.953 114.242 1.00 41.82  ?  510 THR A CG2 1 
ATOM   3699  N  N   . LEU A 1 522 ? 150.035 148.910 113.813 1.00 39.96  ?  511 LEU A N   1 
ATOM   3700  C  CA  . LEU A 1 522 ? 150.035 147.891 112.781 1.00 39.96  ?  511 LEU A CA  1 
ATOM   3701  C  C   . LEU A 1 522 ? 150.360 148.454 111.421 1.00 39.96  ?  511 LEU A C   1 
ATOM   3702  O  O   . LEU A 1 522 ? 150.160 149.636 111.172 1.00 39.96  ?  511 LEU A O   1 
ATOM   3703  C  CB  . LEU A 1 522 ? 148.680 147.185 112.745 1.00 39.96  ?  511 LEU A CB  1 
ATOM   3704  C  CG  . LEU A 1 522 ? 148.163 146.651 114.078 1.00 39.96  ?  511 LEU A CG  1 
ATOM   3705  C  CD1 . LEU A 1 522 ? 146.826 145.957 113.881 1.00 39.96  ?  511 LEU A CD1 1 
ATOM   3706  C  CD2 . LEU A 1 522 ? 149.174 145.710 114.709 1.00 39.96  ?  511 LEU A CD2 1 
ATOM   3707  N  N   . ALA A 1 523 ? 150.879 147.608 110.541 1.00 43.40  ?  512 ALA A N   1 
ATOM   3708  C  CA  . ALA A 1 523 ? 151.216 148.034 109.191 1.00 43.40  ?  512 ALA A CA  1 
ATOM   3709  C  C   . ALA A 1 523 ? 150.814 146.966 108.193 1.00 43.40  ?  512 ALA A C   1 
ATOM   3710  O  O   . ALA A 1 523 ? 150.637 145.816 108.563 1.00 43.40  ?  512 ALA A O   1 
ATOM   3711  C  CB  . ALA A 1 523 ? 152.700 148.330 109.083 1.00 43.40  ?  512 ALA A CB  1 
ATOM   3712  N  N   . ASN A 1 524 ? 150.667 147.343 106.931 1.00 44.65  ?  513 ASN A N   1 
ATOM   3713  C  CA  . ASN A 1 524 ? 150.266 146.401 105.899 1.00 44.65  ?  513 ASN A CA  1 
ATOM   3714  C  C   . ASN A 1 524 ? 151.442 145.584 105.404 1.00 44.65  ?  513 ASN A C   1 
ATOM   3715  O  O   . ASN A 1 524 ? 152.535 146.106 105.241 1.00 44.65  ?  513 ASN A O   1 
ATOM   3716  C  CB  . ASN A 1 524 ? 149.620 147.153 104.732 1.00 44.65  ?  513 ASN A CB  1 
ATOM   3717  C  CG  . ASN A 1 524 ? 148.830 146.249 103.812 1.00 44.65  ?  513 ASN A CG  1 
ATOM   3718  O  OD1 . ASN A 1 524 ? 148.747 146.483 102.611 1.00 44.65  ?  513 ASN A OD1 1 
ATOM   3719  N  ND2 . ASN A 1 524 ? 148.264 145.193 104.372 1.00 44.65  ?  513 ASN A ND2 1 
ATOM   3720  N  N   . ILE A 1 525 ? 151.238 144.295 105.221 1.00 48.62  ?  514 ILE A N   1 
ATOM   3721  C  CA  . ILE A 1 525 ? 152.284 143.415 104.757 1.00 48.62  ?  514 ILE A CA  1 
ATOM   3722  C  C   . ILE A 1 525 ? 151.818 142.775 103.476 1.00 48.62  ?  514 ILE A C   1 
ATOM   3723  O  O   . ILE A 1 525 ? 150.721 142.246 103.416 1.00 48.62  ?  514 ILE A O   1 
ATOM   3724  C  CB  . ILE A 1 525 ? 152.550 142.291 105.770 1.00 48.62  ?  514 ILE A CB  1 
ATOM   3725  C  CG1 . ILE A 1 525 ? 152.177 142.745 107.175 1.00 48.62  ?  514 ILE A CG1 1 
ATOM   3726  C  CG2 . ILE A 1 525 ? 153.994 141.828 105.705 1.00 48.62  ?  514 ILE A CG2 1 
ATOM   3727  C  CD1 . ILE A 1 525 ? 151.961 141.622 108.158 1.00 48.62  ?  514 ILE A CD1 1 
ATOM   3728  N  N   . GLY A 1 526 ? 152.633 142.868 102.439 1.00 50.45  ?  515 GLY A N   1 
ATOM   3729  C  CA  . GLY A 1 526 ? 152.321 142.262 101.167 1.00 50.45  ?  515 GLY A CA  1 
ATOM   3730  C  C   . GLY A 1 526 ? 151.338 142.963 100.271 1.00 50.45  ?  515 GLY A C   1 
ATOM   3731  O  O   . GLY A 1 526 ? 150.910 142.374 99.299  1.00 50.45  ?  515 GLY A O   1 
ATOM   3732  N  N   . ARG A 1 527 ? 151.029 144.226 100.580 1.00 51.57  ?  516 ARG A N   1 
ATOM   3733  C  CA  . ARG A 1 527 ? 150.063 145.026 99.821  1.00 51.57  ?  516 ARG A CA  1 
ATOM   3734  C  C   . ARG A 1 527 ? 148.786 144.214 99.666  1.00 51.57  ?  516 ARG A C   1 
ATOM   3735  O  O   . ARG A 1 527 ? 148.210 144.112 98.584  1.00 51.57  ?  516 ARG A O   1 
ATOM   3736  C  CB  . ARG A 1 527 ? 150.620 145.462 98.461  1.00 51.57  ?  516 ARG A CB  1 
ATOM   3737  C  CG  . ARG A 1 527 ? 151.770 146.451 98.549  1.00 51.57  ?  516 ARG A CG  1 
ATOM   3738  C  CD  . ARG A 1 527 ? 151.347 147.723 99.266  1.00 51.57  ?  516 ARG A CD  1 
ATOM   3739  N  NE  . ARG A 1 527 ? 152.417 148.716 99.298  1.00 51.57  ?  516 ARG A NE  1 
ATOM   3740  C  CZ  . ARG A 1 527 ? 152.592 149.656 98.375  1.00 51.57  ?  516 ARG A CZ  1 
ATOM   3741  N  NH1 . ARG A 1 527 ? 151.765 149.734 97.341  1.00 51.57  1  516 ARG A NH1 1 
ATOM   3742  N  NH2 . ARG A 1 527 ? 153.594 150.518 98.484  1.00 51.57  ?  516 ARG A NH2 1 
ATOM   3743  N  N   . THR A 1 528 ? 148.252 143.645 100.731 1.00 44.44  ?  517 THR A N   1 
ATOM   3744  C  CA  . THR A 1 528 ? 146.984 142.930 100.601 1.00 44.44  ?  517 THR A CA  1 
ATOM   3745  C  C   . THR A 1 528 ? 146.300 143.289 101.895 1.00 44.44  ?  517 THR A C   1 
ATOM   3746  O  O   . THR A 1 528 ? 146.651 144.264 102.505 1.00 44.44  ?  517 THR A O   1 
ATOM   3747  C  CB  . THR A 1 528 ? 147.134 141.392 100.626 1.00 44.44  ?  517 THR A CB  1 
ATOM   3748  O  OG1 . THR A 1 528 ? 148.145 141.007 101.563 1.00 44.44  ?  517 THR A OG1 1 
ATOM   3749  C  CG2 . THR A 1 528 ? 147.517 140.882 99.263  1.00 44.44  ?  517 THR A CG2 1 
ATOM   3750  N  N   . ASN A 1 529 ? 145.321 142.503 102.312 1.00 38.72  ?  518 ASN A N   1 
ATOM   3751  C  CA  . ASN A 1 529 ? 144.463 142.865 103.424 1.00 38.72  ?  518 ASN A CA  1 
ATOM   3752  C  C   . ASN A 1 529 ? 145.007 142.473 104.797 1.00 38.72  ?  518 ASN A C   1 
ATOM   3753  O  O   . ASN A 1 529 ? 144.289 142.522 105.764 1.00 38.72  ?  518 ASN A O   1 
ATOM   3754  C  CB  . ASN A 1 529 ? 143.006 142.425 103.213 1.00 38.72  ?  518 ASN A CB  1 
ATOM   3755  C  CG  . ASN A 1 529 ? 142.840 140.931 103.042 1.00 38.72  ?  518 ASN A CG  1 
ATOM   3756  O  OD1 . ASN A 1 529 ? 143.730 140.241 102.595 1.00 38.72  ?  518 ASN A OD1 1 
ATOM   3757  N  ND2 . ASN A 1 529 ? 141.677 140.439 103.382 1.00 38.72  ?  518 ASN A ND2 1 
ATOM   3758  N  N   . ILE A 1 530 ? 146.273 142.071 104.862 1.00 38.94  ?  519 ILE A N   1 
ATOM   3759  C  CA  . ILE A 1 530 ? 146.931 141.646 106.099 1.00 38.94  ?  519 ILE A CA  1 
ATOM   3760  C  C   . ILE A 1 530 ? 147.665 142.793 106.811 1.00 38.94  ?  519 ILE A C   1 
ATOM   3761  O  O   . ILE A 1 530 ? 148.450 143.495 106.211 1.00 38.94  ?  519 ILE A O   1 
ATOM   3762  C  CB  . ILE A 1 530 ? 147.883 140.455 105.817 1.00 38.94  ?  519 ILE A CB  1 
ATOM   3763  C  CG1 . ILE A 1 530 ? 147.129 139.330 105.110 1.00 38.94  ?  519 ILE A CG1 1 
ATOM   3764  C  CG2 . ILE A 1 530 ? 148.534 139.936 107.087 1.00 38.94  ?  519 ILE A CG2 1 
ATOM   3765  C  CD1 . ILE A 1 530 ? 148.008 138.368 104.357 1.00 38.94  ?  519 ILE A CD1 1 
ATOM   3766  N  N   . TYR A 1 531 ? 147.375 142.995 108.092 1.00 38.75  ?  520 TYR A N   1 
ATOM   3767  C  CA  . TYR A 1 531 ? 148.007 144.045 108.883 1.00 38.75  ?  520 TYR A CA  1 
ATOM   3768  C  C   . TYR A 1 531 ? 148.604 143.411 110.125 1.00 38.75  ?  520 TYR A C   1 
ATOM   3769  O  O   . TYR A 1 531 ? 147.914 142.697 110.853 1.00 38.75  ?  520 TYR A O   1 
ATOM   3770  C  CB  . TYR A 1 531 ? 147.005 145.136 109.256 1.00 38.75  ?  520 TYR A CB  1 
ATOM   3771  C  CG  . TYR A 1 531 ? 146.459 145.857 108.063 1.00 38.75  ?  520 TYR A CG  1 
ATOM   3772  C  CD1 . TYR A 1 531 ? 145.423 145.321 107.324 1.00 38.75  ?  520 TYR A CD1 1 
ATOM   3773  C  CD2 . TYR A 1 531 ? 146.985 147.063 107.664 1.00 38.75  ?  520 TYR A CD2 1 
ATOM   3774  C  CE1 . TYR A 1 531 ? 144.935 145.957 106.235 1.00 38.75  ?  520 TYR A CE1 1 
ATOM   3775  C  CE2 . TYR A 1 531 ? 146.497 147.710 106.574 1.00 38.75  ?  520 TYR A CE2 1 
ATOM   3776  C  CZ  . TYR A 1 531 ? 145.472 147.150 105.861 1.00 38.75  ?  520 TYR A CZ  1 
ATOM   3777  O  OH  . TYR A 1 531 ? 144.975 147.793 104.770 1.00 38.75  ?  520 TYR A OH  1 
ATOM   3778  N  N   . LYS A 1 532 ? 149.877 143.666 110.370 1.00 43.78  ?  521 LYS A N   1 
ATOM   3779  C  CA  . LYS A 1 532 ? 150.575 143.065 111.496 1.00 43.78  ?  521 LYS A CA  1 
ATOM   3780  C  C   . LYS A 1 532 ? 151.417 144.112 112.202 1.00 43.78  ?  521 LYS A C   1 
ATOM   3781  O  O   . LYS A 1 532 ? 151.497 145.255 111.781 1.00 43.78  ?  521 LYS A O   1 
ATOM   3782  C  CB  . LYS A 1 532 ? 151.437 141.888 111.042 1.00 43.78  ?  521 LYS A CB  1 
ATOM   3783  C  CG  . LYS A 1 532 ? 150.648 140.767 110.420 1.00 43.78  ?  521 LYS A CG  1 
ATOM   3784  C  CD  . LYS A 1 532 ? 151.124 139.432 110.882 1.00 43.78  ?  521 LYS A CD  1 
ATOM   3785  C  CE  . LYS A 1 532 ? 150.047 138.395 110.728 1.00 43.78  ?  521 LYS A CE  1 
ATOM   3786  N  NZ  . LYS A 1 532 ? 148.815 138.791 111.457 1.00 43.78  1  521 LYS A NZ  1 
ATOM   3787  N  N   . ASN A 1 533 ? 152.056 143.698 113.288 1.00 48.83  ?  522 ASN A N   1 
ATOM   3788  C  CA  . ASN A 1 533 ? 152.857 144.609 114.089 1.00 48.83  ?  522 ASN A CA  1 
ATOM   3789  C  C   . ASN A 1 533 ? 153.925 145.279 113.239 1.00 48.83  ?  522 ASN A C   1 
ATOM   3790  O  O   . ASN A 1 533 ? 154.732 144.615 112.590 1.00 48.83  ?  522 ASN A O   1 
ATOM   3791  C  CB  . ASN A 1 533 ? 153.492 143.854 115.246 1.00 48.83  ?  522 ASN A CB  1 
ATOM   3792  C  CG  . ASN A 1 533 ? 154.033 144.765 116.314 1.00 48.83  ?  522 ASN A CG  1 
ATOM   3793  O  OD1 . ASN A 1 533 ? 154.382 145.908 116.059 1.00 48.83  ?  522 ASN A OD1 1 
ATOM   3794  N  ND2 . ASN A 1 533 ? 154.113 144.255 117.525 1.00 48.83  ?  522 ASN A ND2 1 
ATOM   3795  N  N   . LYS A 1 534 ? 153.921 146.608 113.258 1.00 50.38  ?  523 LYS A N   1 
ATOM   3796  C  CA  . LYS A 1 534 ? 154.798 147.416 112.424 1.00 50.38  ?  523 LYS A CA  1 
ATOM   3797  C  C   . LYS A 1 534 ? 156.273 147.146 112.686 1.00 50.38  ?  523 LYS A C   1 
ATOM   3798  O  O   . LYS A 1 534 ? 157.111 147.453 111.836 1.00 50.38  ?  523 LYS A O   1 
ATOM   3799  C  CB  . LYS A 1 534 ? 154.454 148.880 112.664 1.00 50.38  ?  523 LYS A CB  1 
ATOM   3800  C  CG  . LYS A 1 534 ? 155.268 149.883 111.931 1.00 50.38  ?  523 LYS A CG  1 
ATOM   3801  C  CD  . LYS A 1 534 ? 155.214 151.202 112.657 1.00 50.38  ?  523 LYS A CD  1 
ATOM   3802  C  CE  . LYS A 1 534 ? 156.308 152.127 112.186 1.00 50.38  ?  523 LYS A CE  1 
ATOM   3803  N  NZ  . LYS A 1 534 ? 156.190 153.460 112.823 1.00 50.38  1  523 LYS A NZ  1 
ATOM   3804  N  N   . LYS A 1 535 ? 156.606 146.556 113.827 1.00 58.83  ?  524 LYS A N   1 
ATOM   3805  C  CA  . LYS A 1 535 ? 157.983 146.303 114.212 1.00 58.83  ?  524 LYS A CA  1 
ATOM   3806  C  C   . LYS A 1 535 ? 158.441 144.882 113.930 1.00 58.83  ?  524 LYS A C   1 
ATOM   3807  O  O   . LYS A 1 535 ? 159.591 144.554 114.217 1.00 58.83  ?  524 LYS A O   1 
ATOM   3808  C  CB  . LYS A 1 535 ? 158.165 146.599 115.698 1.00 58.83  ?  524 LYS A CB  1 
ATOM   3809  C  CG  . LYS A 1 535 ? 158.064 148.053 116.045 1.00 58.83  ?  524 LYS A CG  1 
ATOM   3810  C  CD  . LYS A 1 535 ? 158.739 148.339 117.359 1.00 58.83  ?  524 LYS A CD  1 
ATOM   3811  C  CE  . LYS A 1 535 ? 157.903 147.854 118.514 1.00 58.83  ?  524 LYS A CE  1 
ATOM   3812  N  NZ  . LYS A 1 535 ? 158.244 148.589 119.755 1.00 58.83  1  524 LYS A NZ  1 
ATOM   3813  N  N   . ASP A 1 536 ? 157.587 144.036 113.365 1.00 58.90  ?  525 ASP A N   1 
ATOM   3814  C  CA  . ASP A 1 536 ? 157.867 142.610 113.298 1.00 58.90  ?  525 ASP A CA  1 
ATOM   3815  C  C   . ASP A 1 536 ? 158.386 142.143 111.951 1.00 58.90  ?  525 ASP A C   1 
ATOM   3816  O  O   . ASP A 1 536 ? 159.112 141.151 111.901 1.00 58.90  ?  525 ASP A O   1 
ATOM   3817  C  CB  . ASP A 1 536 ? 156.612 141.810 113.646 1.00 58.90  ?  525 ASP A CB  1 
ATOM   3818  C  CG  . ASP A 1 536 ? 156.354 141.749 115.127 1.00 58.90  ?  525 ASP A CG  1 
ATOM   3819  O  OD1 . ASP A 1 536 ? 157.147 142.323 115.892 1.00 58.90  ?  525 ASP A OD1 1 
ATOM   3820  O  OD2 . ASP A 1 536 ? 155.356 141.123 115.533 1.00 58.90  -1 525 ASP A OD2 1 
ATOM   3821  N  N   . TYR A 1 537 ? 158.042 142.814 110.861 1.00 57.22  ?  526 TYR A N   1 
ATOM   3822  C  CA  . TYR A 1 537 ? 158.399 142.342 109.535 1.00 57.22  ?  526 TYR A CA  1 
ATOM   3823  C  C   . TYR A 1 537 ? 159.111 143.438 108.764 1.00 57.22  ?  526 TYR A C   1 
ATOM   3824  O  O   . TYR A 1 537 ? 159.055 144.615 109.118 1.00 57.22  ?  526 TYR A O   1 
ATOM   3825  C  CB  . TYR A 1 537 ? 157.168 141.877 108.747 1.00 57.22  ?  526 TYR A CB  1 
ATOM   3826  C  CG  . TYR A 1 537 ? 156.364 140.819 109.444 1.00 57.22  ?  526 TYR A CG  1 
ATOM   3827  C  CD1 . TYR A 1 537 ? 156.558 139.483 109.166 1.00 57.22  ?  526 TYR A CD1 1 
ATOM   3828  C  CD2 . TYR A 1 537 ? 155.416 141.156 110.389 1.00 57.22  ?  526 TYR A CD2 1 
ATOM   3829  C  CE1 . TYR A 1 537 ? 155.832 138.518 109.808 1.00 57.22  ?  526 TYR A CE1 1 
ATOM   3830  C  CE2 . TYR A 1 537 ? 154.694 140.201 111.036 1.00 57.22  ?  526 TYR A CE2 1 
ATOM   3831  C  CZ  . TYR A 1 537 ? 154.900 138.884 110.741 1.00 57.22  ?  526 TYR A CZ  1 
ATOM   3832  O  OH  . TYR A 1 537 ? 154.169 137.925 111.390 1.00 57.22  ?  526 TYR A OH  1 
ATOM   3833  N  N   . TYR A 1 538 ? 159.786 143.032 107.700 1.00 64.79  ?  527 TYR A N   1 
ATOM   3834  C  CA  . TYR A 1 538 ? 160.414 143.975 106.793 1.00 64.79  ?  527 TYR A CA  1 
ATOM   3835  C  C   . TYR A 1 538 ? 159.460 144.337 105.664 1.00 64.79  ?  527 TYR A C   1 
ATOM   3836  O  O   . TYR A 1 538 ? 158.553 143.580 105.317 1.00 64.79  ?  527 TYR A O   1 
ATOM   3837  C  CB  . TYR A 1 538 ? 161.695 143.392 106.204 1.00 64.79  ?  527 TYR A CB  1 
ATOM   3838  C  CG  . TYR A 1 538 ? 162.830 143.258 107.180 1.00 64.79  ?  527 TYR A CG  1 
ATOM   3839  C  CD1 . TYR A 1 538 ? 163.520 144.372 107.625 1.00 64.79  ?  527 TYR A CD1 1 
ATOM   3840  C  CD2 . TYR A 1 538 ? 163.226 142.016 107.643 1.00 64.79  ?  527 TYR A CD2 1 
ATOM   3841  C  CE1 . TYR A 1 538 ? 164.562 144.254 108.514 1.00 64.79  ?  527 TYR A CE1 1 
ATOM   3842  C  CE2 . TYR A 1 538 ? 164.266 141.888 108.530 1.00 64.79  ?  527 TYR A CE2 1 
ATOM   3843  C  CZ  . TYR A 1 538 ? 164.932 143.011 108.963 1.00 64.79  ?  527 TYR A CZ  1 
ATOM   3844  O  OH  . TYR A 1 538 ? 165.974 142.890 109.850 1.00 64.79  ?  527 TYR A OH  1 
ATOM   3845  N  N   . ASP A 1 539 ? 159.686 145.513 105.085 1.00 62.93  ?  528 ASP A N   1 
ATOM   3846  C  CA  . ASP A 1 539 ? 158.946 145.977 103.916 1.00 62.93  ?  528 ASP A CA  1 
ATOM   3847  C  C   . ASP A 1 539 ? 157.455 146.115 104.200 1.00 62.93  ?  528 ASP A C   1 
ATOM   3848  O  O   . ASP A 1 539 ? 156.618 145.795 103.358 1.00 62.93  ?  528 ASP A O   1 
ATOM   3849  C  CB  . ASP A 1 539 ? 159.184 145.057 102.716 1.00 62.93  ?  528 ASP A CB  1 
ATOM   3850  C  CG  . ASP A 1 539 ? 160.618 145.096 102.236 1.00 62.93  ?  528 ASP A CG  1 
ATOM   3851  O  OD1 . ASP A 1 539 ? 160.880 144.664 101.097 1.00 62.93  ?  528 ASP A OD1 1 
ATOM   3852  O  OD2 . ASP A 1 539 ? 161.486 145.568 102.997 1.00 62.93  -1 528 ASP A OD2 1 
ATOM   3853  N  N   . MET A 1 540 ? 157.109 146.586 105.389 1.00 54.74  ?  529 MET A N   1 
ATOM   3854  C  CA  . MET A 1 540 ? 155.728 146.900 105.704 1.00 54.74  ?  529 MET A CA  1 
ATOM   3855  C  C   . MET A 1 540 ? 155.388 148.292 105.192 1.00 54.74  ?  529 MET A C   1 
ATOM   3856  O  O   . MET A 1 540 ? 156.258 149.054 104.775 1.00 54.74  ?  529 MET A O   1 
ATOM   3857  C  CB  . MET A 1 540 ? 155.489 146.801 107.204 1.00 54.74  ?  529 MET A CB  1 
ATOM   3858  C  CG  . MET A 1 540 ? 156.025 145.526 107.800 1.00 54.74  ?  529 MET A CG  1 
ATOM   3859  S  SD  . MET A 1 540 ? 155.582 145.295 109.517 1.00 54.74  ?  529 MET A SD  1 
ATOM   3860  C  CE  . MET A 1 540 ? 153.869 144.859 109.349 1.00 54.74  ?  529 MET A CE  1 
ATOM   3861  N  N   . TYR A 1 541 ? 154.104 148.619 105.219 1.00 51.22  ?  530 TYR A N   1 
ATOM   3862  C  CA  . TYR A 1 541 ? 153.616 149.840 104.592 1.00 51.22  ?  530 TYR A CA  1 
ATOM   3863  C  C   . TYR A 1 541 ? 152.516 150.440 105.451 1.00 51.22  ?  530 TYR A C   1 
ATOM   3864  O  O   . TYR A 1 541 ? 151.524 149.774 105.745 1.00 51.22  ?  530 TYR A O   1 
ATOM   3865  C  CB  . TYR A 1 541 ? 153.111 149.552 103.182 1.00 51.22  ?  530 TYR A CB  1 
ATOM   3866  C  CG  . TYR A 1 541 ? 152.321 150.670 102.561 1.00 51.22  ?  530 TYR A CG  1 
ATOM   3867  C  CD1 . TYR A 1 541 ? 150.951 150.577 102.416 1.00 51.22  ?  530 TYR A CD1 1 
ATOM   3868  C  CD2 . TYR A 1 541 ? 152.948 151.811 102.107 1.00 51.22  ?  530 TYR A CD2 1 
ATOM   3869  C  CE1 . TYR A 1 541 ? 150.231 151.589 101.848 1.00 51.22  ?  530 TYR A CE1 1 
ATOM   3870  C  CE2 . TYR A 1 541 ? 152.234 152.830 101.537 1.00 51.22  ?  530 TYR A CE2 1 
ATOM   3871  C  CZ  . TYR A 1 541 ? 150.877 152.715 101.408 1.00 51.22  ?  530 TYR A CZ  1 
ATOM   3872  O  OH  . TYR A 1 541 ? 150.163 153.736 100.835 1.00 51.22  ?  530 TYR A OH  1 
ATOM   3873  N  N   . GLU A 1 542 ? 152.696 151.690 105.862 1.00 52.45  ?  531 GLU A N   1 
ATOM   3874  C  CA  . GLU A 1 542 ? 151.617 152.458 106.455 1.00 52.45  ?  531 GLU A CA  1 
ATOM   3875  C  C   . GLU A 1 542 ? 151.125 153.466 105.438 1.00 52.45  ?  531 GLU A C   1 
ATOM   3876  O  O   . GLU A 1 542 ? 151.936 154.255 104.939 1.00 52.45  ?  531 GLU A O   1 
ATOM   3877  C  CB  . GLU A 1 542 ? 152.080 153.183 107.709 1.00 52.45  ?  531 GLU A CB  1 
ATOM   3878  C  CG  . GLU A 1 542 ? 152.788 152.343 108.732 1.00 52.45  ?  531 GLU A CG  1 
ATOM   3879  C  CD  . GLU A 1 542 ? 152.928 153.069 110.050 1.00 52.45  ?  531 GLU A CD  1 
ATOM   3880  O  OE1 . GLU A 1 542 ? 151.897 153.394 110.670 1.00 52.45  ?  531 GLU A OE1 1 
ATOM   3881  O  OE2 . GLU A 1 542 ? 154.069 153.337 110.463 1.00 52.45  -1 531 GLU A OE2 1 
ATOM   3882  N  N   . PRO A 1 543 ? 149.842 153.485 105.093 1.00 51.80  ?  532 PRO A N   1 
ATOM   3883  C  CA  . PRO A 1 543 ? 149.341 154.557 104.233 1.00 51.80  ?  532 PRO A CA  1 
ATOM   3884  C  C   . PRO A 1 543 ? 149.560 155.902 104.900 1.00 51.80  ?  532 PRO A C   1 
ATOM   3885  O  O   . PRO A 1 543 ? 149.429 156.045 106.115 1.00 51.80  ?  532 PRO A O   1 
ATOM   3886  C  CB  . PRO A 1 543 ? 147.854 154.231 104.077 1.00 51.80  ?  532 PRO A CB  1 
ATOM   3887  C  CG  . PRO A 1 543 ? 147.554 153.247 105.137 1.00 51.80  ?  532 PRO A CG  1 
ATOM   3888  C  CD  . PRO A 1 543 ? 148.798 152.511 105.432 1.00 51.80  ?  532 PRO A CD  1 
ATOM   3889  N  N   . GLU A 1 544 ? 149.919 156.888 104.093 1.00 57.05  ?  533 GLU A N   1 
ATOM   3890  C  CA  . GLU A 1 544 ? 150.453 158.132 104.628 1.00 57.05  ?  533 GLU A CA  1 
ATOM   3891  C  C   . GLU A 1 544 ? 149.357 158.882 105.372 1.00 57.05  ?  533 GLU A C   1 
ATOM   3892  O  O   . GLU A 1 544 ? 148.277 159.117 104.826 1.00 57.05  ?  533 GLU A O   1 
ATOM   3893  C  CB  . GLU A 1 544 ? 151.026 158.975 103.494 1.00 57.05  ?  533 GLU A CB  1 
ATOM   3894  C  CG  . GLU A 1 544 ? 152.154 159.912 103.892 1.00 57.05  ?  533 GLU A CG  1 
ATOM   3895  C  CD  . GLU A 1 544 ? 151.680 161.193 104.533 1.00 57.05  ?  533 GLU A CD  1 
ATOM   3896  O  OE1 . GLU A 1 544 ? 150.790 161.851 103.955 1.00 57.05  ?  533 GLU A OE1 1 
ATOM   3897  O  OE2 . GLU A 1 544 ? 152.206 161.549 105.611 1.00 57.05  -1 533 GLU A OE2 1 
ATOM   3898  N  N   . GLY A 1 545 ? 149.628 159.247 106.619 1.00 49.82  ?  534 GLY A N   1 
ATOM   3899  C  CA  . GLY A 1 545 ? 148.665 159.943 107.438 1.00 49.82  ?  534 GLY A CA  1 
ATOM   3900  C  C   . GLY A 1 545 ? 147.694 159.063 108.182 1.00 49.82  ?  534 GLY A C   1 
ATOM   3901  O  O   . GLY A 1 545 ? 146.755 159.583 108.785 1.00 49.82  ?  534 GLY A O   1 
ATOM   3902  N  N   . VAL A 1 546 ? 147.888 157.753 108.162 1.00 47.71  ?  535 VAL A N   1 
ATOM   3903  C  CA  . VAL A 1 546 ? 147.008 156.802 108.822 1.00 47.71  ?  535 VAL A CA  1 
ATOM   3904  C  C   . VAL A 1 546 ? 147.796 156.076 109.897 1.00 47.71  ?  535 VAL A C   1 
ATOM   3905  O  O   . VAL A 1 546 ? 148.911 155.609 109.651 1.00 47.71  ?  535 VAL A O   1 
ATOM   3906  C  CB  . VAL A 1 546 ? 146.411 155.801 107.813 1.00 47.71  ?  535 VAL A CB  1 
ATOM   3907  C  CG1 . VAL A 1 546 ? 145.495 154.829 108.510 1.00 47.71  ?  535 VAL A CG1 1 
ATOM   3908  C  CG2 . VAL A 1 546 ? 145.678 156.531 106.722 1.00 47.71  ?  535 VAL A CG2 1 
ATOM   3909  N  N   . LYS A 1 547 ? 147.222 155.988 111.091 1.00 44.79  ?  536 LYS A N   1 
ATOM   3910  C  CA  . LYS A 1 547 ? 147.781 155.209 112.185 1.00 44.79  ?  536 LYS A CA  1 
ATOM   3911  C  C   . LYS A 1 547 ? 146.799 154.109 112.544 1.00 44.79  ?  536 LYS A C   1 
ATOM   3912  O  O   . LYS A 1 547 ? 145.603 154.364 112.673 1.00 44.79  ?  536 LYS A O   1 
ATOM   3913  C  CB  . LYS A 1 547 ? 148.060 156.081 113.408 1.00 44.79  ?  536 LYS A CB  1 
ATOM   3914  C  CG  . LYS A 1 547 ? 149.352 156.846 113.345 1.00 44.79  ?  536 LYS A CG  1 
ATOM   3915  C  CD  . LYS A 1 547 ? 150.529 155.958 113.589 1.00 44.79  ?  536 LYS A CD  1 
ATOM   3916  C  CE  . LYS A 1 547 ? 151.812 156.685 113.304 1.00 44.79  ?  536 LYS A CE  1 
ATOM   3917  N  NZ  . LYS A 1 547 ? 152.973 155.780 113.475 1.00 44.79  1  536 LYS A NZ  1 
ATOM   3918  N  N   . ILE A 1 548 ? 147.300 152.893 112.700 1.00 38.44  ?  537 ILE A N   1 
ATOM   3919  C  CA  . ILE A 1 548 ? 146.488 151.752 113.100 1.00 38.44  ?  537 ILE A CA  1 
ATOM   3920  C  C   . ILE A 1 548 ? 147.009 151.275 114.444 1.00 38.44  ?  537 ILE A C   1 
ATOM   3921  O  O   . ILE A 1 548 ? 148.143 150.805 114.548 1.00 38.44  ?  537 ILE A O   1 
ATOM   3922  C  CB  . ILE A 1 548 ? 146.516 150.632 112.055 1.00 38.44  ?  537 ILE A CB  1 
ATOM   3923  C  CG1 . ILE A 1 548 ? 146.045 151.162 110.708 1.00 38.44  ?  537 ILE A CG1 1 
ATOM   3924  C  CG2 . ILE A 1 548 ? 145.647 149.488 112.495 1.00 38.44  ?  537 ILE A CG2 1 
ATOM   3925  C  CD1 . ILE A 1 548 ? 146.647 150.467 109.553 1.00 38.44  ?  537 ILE A CD1 1 
ATOM   3926  N  N   . PHE A 1 549 ? 146.186 151.390 115.474 1.00 39.65  ?  538 PHE A N   1 
ATOM   3927  C  CA  . PHE A 1 549 ? 146.584 151.079 116.836 1.00 39.65  ?  538 PHE A CA  1 
ATOM   3928  C  C   . PHE A 1 549 ? 145.789 149.885 117.337 1.00 39.65  ?  538 PHE A C   1 
ATOM   3929  O  O   . PHE A 1 549 ? 144.572 149.830 117.162 1.00 39.65  ?  538 PHE A O   1 
ATOM   3930  C  CB  . PHE A 1 549 ? 146.367 152.289 117.741 1.00 39.65  ?  538 PHE A CB  1 
ATOM   3931  C  CG  . PHE A 1 549 ? 146.925 152.128 119.113 1.00 39.65  ?  538 PHE A CG  1 
ATOM   3932  C  CD1 . PHE A 1 549 ? 148.282 152.078 119.320 1.00 39.65  ?  538 PHE A CD1 1 
ATOM   3933  C  CD2 . PHE A 1 549 ? 146.090 152.032 120.201 1.00 39.65  ?  538 PHE A CD2 1 
ATOM   3934  C  CE1 . PHE A 1 549 ? 148.784 151.932 120.573 1.00 39.65  ?  538 PHE A CE1 1 
ATOM   3935  C  CE2 . PHE A 1 549 ? 146.596 151.887 121.452 1.00 39.65  ?  538 PHE A CE2 1 
ATOM   3936  C  CZ  . PHE A 1 549 ? 147.941 151.839 121.636 1.00 39.65  ?  538 PHE A CZ  1 
ATOM   3937  N  N   . ARG A 1 550 ? 146.473 148.940 117.966 1.00 43.93  ?  539 ARG A N   1 
ATOM   3938  C  CA  . ARG A 1 550 ? 145.850 147.734 118.486 1.00 43.93  ?  539 ARG A CA  1 
ATOM   3939  C  C   . ARG A 1 550 ? 146.123 147.624 119.978 1.00 43.93  ?  539 ARG A C   1 
ATOM   3940  O  O   . ARG A 1 550 ? 147.271 147.751 120.413 1.00 43.93  ?  539 ARG A O   1 
ATOM   3941  C  CB  . ARG A 1 550 ? 146.371 146.503 117.756 1.00 43.93  ?  539 ARG A CB  1 
ATOM   3942  C  CG  . ARG A 1 550 ? 145.868 145.214 118.310 1.00 43.93  ?  539 ARG A CG  1 
ATOM   3943  C  CD  . ARG A 1 550 ? 146.513 144.051 117.623 1.00 43.93  ?  539 ARG A CD  1 
ATOM   3944  N  NE  . ARG A 1 550 ? 146.301 142.814 118.360 1.00 43.93  ?  539 ARG A NE  1 
ATOM   3945  C  CZ  . ARG A 1 550 ? 145.246 142.025 118.206 1.00 43.93  ?  539 ARG A CZ  1 
ATOM   3946  N  NH1 . ARG A 1 550 ? 145.138 140.920 118.919 1.00 43.93  1  539 ARG A NH1 1 
ATOM   3947  N  NH2 . ARG A 1 550 ? 144.301 142.341 117.339 1.00 43.93  ?  539 ARG A NH2 1 
ATOM   3948  N  N   . CYS A 1 551 ? 145.063 147.403 120.753 1.00 48.32  ?  540 CYS A N   1 
ATOM   3949  C  CA  . CYS A 1 551 ? 145.154 147.022 122.154 1.00 48.32  ?  540 CYS A CA  1 
ATOM   3950  C  C   . CYS A 1 551 ? 144.653 145.596 122.292 1.00 48.32  ?  540 CYS A C   1 
ATOM   3951  O  O   . CYS A 1 551 ? 143.473 145.337 122.036 1.00 48.32  ?  540 CYS A O   1 
ATOM   3952  C  CB  . CYS A 1 551 ? 144.339 147.958 123.041 1.00 48.32  ?  540 CYS A CB  1 
ATOM   3953  S  SG  . CYS A 1 551 ? 144.483 147.623 124.805 1.00 48.32  ?  540 CYS A SG  1 
ATOM   3954  N  N   . PRO A 1 552 ? 145.561 144.648 122.506 1.00 47.48  ?  541 PRO A N   1 
ATOM   3955  C  CA  . PRO A 1 552 ? 145.168 143.239 122.503 1.00 47.48  ?  541 PRO A CA  1 
ATOM   3956  C  C   . PRO A 1 552 ? 144.538 142.771 123.790 1.00 47.48  ?  541 PRO A C   1 
ATOM   3957  O  O   . PRO A 1 552 ? 144.821 141.682 124.242 1.00 47.48  ?  541 PRO A O   1 
ATOM   3958  C  CB  . PRO A 1 552 ? 146.501 142.545 122.309 1.00 47.48  ?  541 PRO A CB  1 
ATOM   3959  C  CG  . PRO A 1 552 ? 147.455 143.419 123.044 1.00 47.48  ?  541 PRO A CG  1 
ATOM   3960  C  CD  . PRO A 1 552 ? 146.945 144.825 122.970 1.00 47.48  ?  541 PRO A CD  1 
ATOM   3961  N  N   . SER A 1 553 ? 143.641 143.562 124.335 1.00 45.56  ?  542 SER A N   1 
ATOM   3962  C  CA  . SER A 1 553 ? 143.057 143.233 125.600 1.00 45.56  ?  542 SER A CA  1 
ATOM   3963  C  C   . SER A 1 553 ? 141.766 143.985 125.777 1.00 45.56  ?  542 SER A C   1 
ATOM   3964  O  O   . SER A 1 553 ? 141.524 144.948 125.074 1.00 45.56  ?  542 SER A O   1 
ATOM   3965  C  CB  . SER A 1 553 ? 144.071 143.673 126.659 1.00 45.56  ?  542 SER A CB  1 
ATOM   3966  O  OG  . SER A 1 553 ? 143.670 143.406 127.974 1.00 45.56  ?  542 SER A OG  1 
ATOM   3967  N  N   . PRO A 1 554 ? 140.895 143.518 126.679 1.00 44.61  ?  543 PRO A N   1 
ATOM   3968  C  CA  . PRO A 1 554 ? 139.696 144.307 126.954 1.00 44.61  ?  543 PRO A CA  1 
ATOM   3969  C  C   . PRO A 1 554 ? 140.126 145.553 127.719 1.00 44.61  ?  543 PRO A C   1 
ATOM   3970  O  O   . PRO A 1 554 ? 141.042 145.504 128.515 1.00 44.61  ?  543 PRO A O   1 
ATOM   3971  C  CB  . PRO A 1 554 ? 138.869 143.399 127.859 1.00 44.61  ?  543 PRO A CB  1 
ATOM   3972  C  CG  . PRO A 1 554 ? 139.813 142.376 128.368 1.00 44.61  ?  543 PRO A CG  1 
ATOM   3973  C  CD  . PRO A 1 554 ? 140.835 142.190 127.302 1.00 44.61  ?  543 PRO A CD  1 
ATOM   3974  N  N   . ILE A 1 555 ? 139.454 146.660 127.489 1.00 45.37  ?  544 ILE A N   1 
ATOM   3975  C  CA  . ILE A 1 555 ? 139.798 147.898 128.139 1.00 45.37  ?  544 ILE A CA  1 
ATOM   3976  C  C   . ILE A 1 555 ? 138.765 148.192 129.206 1.00 45.37  ?  544 ILE A C   1 
ATOM   3977  O  O   . ILE A 1 555 ? 137.587 148.212 128.946 1.00 45.37  ?  544 ILE A O   1 
ATOM   3978  C  CB  . ILE A 1 555 ? 139.920 149.018 127.099 1.00 45.37  ?  544 ILE A CB  1 
ATOM   3979  C  CG1 . ILE A 1 555 ? 140.751 148.507 125.922 1.00 45.37  ?  544 ILE A CG1 1 
ATOM   3980  C  CG2 . ILE A 1 555 ? 140.562 150.252 127.703 1.00 45.37  ?  544 ILE A CG2 1 
ATOM   3981  C  CD1 . ILE A 1 555 ? 140.686 149.360 124.684 1.00 45.37  ?  544 ILE A CD1 1 
ATOM   3982  N  N   . TYR A 1 556 ? 139.237 148.408 130.422 1.00 43.50  ?  545 TYR A N   1 
ATOM   3983  C  CA  . TYR A 1 556 ? 138.386 148.658 131.574 1.00 43.50  ?  545 TYR A CA  1 
ATOM   3984  C  C   . TYR A 1 556 ? 139.118 149.543 132.569 1.00 43.50  ?  545 TYR A C   1 
ATOM   3985  O  O   . TYR A 1 556 ? 140.165 150.042 132.271 1.00 43.50  ?  545 TYR A O   1 
ATOM   3986  C  CB  . TYR A 1 556 ? 137.926 147.347 132.210 1.00 43.50  ?  545 TYR A CB  1 
ATOM   3987  C  CG  . TYR A 1 556 ? 139.062 146.521 132.709 1.00 43.50  ?  545 TYR A CG  1 
ATOM   3988  C  CD1 . TYR A 1 556 ? 139.933 145.924 131.827 1.00 43.50  ?  545 TYR A CD1 1 
ATOM   3989  C  CD2 . TYR A 1 556 ? 139.287 146.366 134.062 1.00 43.50  ?  545 TYR A CD2 1 
ATOM   3990  C  CE1 . TYR A 1 556 ? 140.992 145.193 132.274 1.00 43.50  ?  545 TYR A CE1 1 
ATOM   3991  C  CE2 . TYR A 1 556 ? 140.342 145.624 134.520 1.00 43.50  ?  545 TYR A CE2 1 
ATOM   3992  C  CZ  . TYR A 1 556 ? 141.190 145.041 133.618 1.00 43.50  ?  545 TYR A CZ  1 
ATOM   3993  O  OH  . TYR A 1 556 ? 142.255 144.301 134.055 1.00 43.50  ?  545 TYR A OH  1 
ATOM   3994  N  N   . PHE A 1 557 ? 138.515 149.801 133.716 1.00 43.57  ?  546 PHE A N   1 
ATOM   3995  C  CA  . PHE A 1 557 ? 139.093 150.641 134.762 1.00 43.57  ?  546 PHE A CA  1 
ATOM   3996  C  C   . PHE A 1 557 ? 140.600 150.521 135.034 1.00 43.57  ?  546 PHE A C   1 
ATOM   3997  O  O   . PHE A 1 557 ? 141.261 151.533 135.190 1.00 43.57  ?  546 PHE A O   1 
ATOM   3998  C  CB  . PHE A 1 557 ? 138.269 150.556 136.079 1.00 43.57  ?  546 PHE A CB  1 
ATOM   3999  C  CG  . PHE A 1 557 ? 138.491 149.299 136.876 1.00 43.57  ?  546 PHE A CG  1 
ATOM   4000  C  CD1 . PHE A 1 557 ? 137.685 148.208 136.682 1.00 43.57  ?  546 PHE A CD1 1 
ATOM   4001  C  CD2 . PHE A 1 557 ? 139.503 149.217 137.817 1.00 43.57  ?  546 PHE A CD2 1 
ATOM   4002  C  CE1 . PHE A 1 557 ? 137.886 147.054 137.387 1.00 43.57  ?  546 PHE A CE1 1 
ATOM   4003  C  CE2 . PHE A 1 557 ? 139.729 148.060 138.501 1.00 43.57  ?  546 PHE A CE2 1 
ATOM   4004  C  CZ  . PHE A 1 557 ? 138.910 146.979 138.291 1.00 43.57  ?  546 PHE A CZ  1 
ATOM   4005  N  N   . ALA A 1 558 ? 141.160 149.318 135.053 1.00 43.16  ?  547 ALA A N   1 
ATOM   4006  C  CA  . ALA A 1 558 ? 142.570 149.190 135.387 1.00 43.16  ?  547 ALA A CA  1 
ATOM   4007  C  C   . ALA A 1 558 ? 143.465 149.340 134.177 1.00 43.16  ?  547 ALA A C   1 
ATOM   4008  O  O   . ALA A 1 558 ? 144.664 149.089 134.268 1.00 43.16  ?  547 ALA A O   1 
ATOM   4009  C  CB  . ALA A 1 558 ? 142.831 147.846 136.058 1.00 43.16  ?  547 ALA A CB  1 
ATOM   4010  N  N   . ASN A 1 559 ? 142.902 149.779 133.065 1.00 43.51  ?  548 ASN A N   1 
ATOM   4011  C  CA  . ASN A 1 559 ? 143.520 149.667 131.760 1.00 43.51  ?  548 ASN A CA  1 
ATOM   4012  C  C   . ASN A 1 559 ? 143.545 150.956 130.975 1.00 43.51  ?  548 ASN A C   1 
ATOM   4013  O  O   . ASN A 1 559 ? 144.473 151.150 130.189 1.00 43.51  ?  548 ASN A O   1 
ATOM   4014  C  CB  . ASN A 1 559 ? 142.764 148.625 130.925 1.00 43.51  ?  548 ASN A CB  1 
ATOM   4015  C  CG  . ASN A 1 559 ? 143.647 147.584 130.399 1.00 43.51  ?  548 ASN A CG  1 
ATOM   4016  O  OD1 . ASN A 1 559 ? 144.854 147.716 130.467 1.00 43.51  ?  548 ASN A OD1 1 
ATOM   4017  N  ND2 . ASN A 1 559 ? 143.072 146.524 129.878 1.00 43.51  ?  548 ASN A ND2 1 
ATOM   4018  N  N   . ILE A 1 560 ? 142.567 151.838 131.154 1.00 43.64  ?  549 ILE A N   1 
ATOM   4019  C  CA  . ILE A 1 560 ? 142.288 152.852 130.152 1.00 43.64  ?  549 ILE A CA  1 
ATOM   4020  C  C   . ILE A 1 560 ? 143.298 153.993 130.197 1.00 43.64  ?  549 ILE A C   1 
ATOM   4021  O  O   . ILE A 1 560 ? 143.591 154.601 129.164 1.00 43.64  ?  549 ILE A O   1 
ATOM   4022  C  CB  . ILE A 1 560 ? 140.836 153.334 130.318 1.00 43.64  ?  549 ILE A CB  1 
ATOM   4023  C  CG1 . ILE A 1 560 ? 140.523 154.455 129.337 1.00 43.64  ?  549 ILE A CG1 1 
ATOM   4024  C  CG2 . ILE A 1 560 ? 140.545 153.721 131.755 1.00 43.64  ?  549 ILE A CG2 1 
ATOM   4025  C  CD1 . ILE A 1 560 ? 140.259 154.002 127.951 1.00 43.64  ?  549 ILE A CD1 1 
ATOM   4026  N  N   . GLY A 1 561 ? 143.868 154.290 131.363 1.00 42.89  ?  550 GLY A N   1 
ATOM   4027  C  CA  . GLY A 1 561 ? 144.933 155.276 131.414 1.00 42.89  ?  550 GLY A CA  1 
ATOM   4028  C  C   . GLY A 1 561 ? 146.173 154.822 130.674 1.00 42.89  ?  550 GLY A C   1 
ATOM   4029  O  O   . GLY A 1 561 ? 146.791 155.597 129.940 1.00 42.89  ?  550 GLY A O   1 
ATOM   4030  N  N   . PHE A 1 562 ? 146.547 153.558 130.852 1.00 41.96  ?  551 PHE A N   1 
ATOM   4031  C  CA  . PHE A 1 562 ? 147.651 152.984 130.098 1.00 41.96  ?  551 PHE A CA  1 
ATOM   4032  C  C   . PHE A 1 562 ? 147.360 152.996 128.605 1.00 41.96  ?  551 PHE A C   1 
ATOM   4033  O  O   . PHE A 1 562 ? 148.246 153.282 127.794 1.00 41.96  ?  551 PHE A O   1 
ATOM   4034  C  CB  . PHE A 1 562 ? 147.911 151.563 130.589 1.00 41.96  ?  551 PHE A CB  1 
ATOM   4035  C  CG  . PHE A 1 562 ? 149.150 150.946 130.039 1.00 41.96  ?  551 PHE A CG  1 
ATOM   4036  C  CD1 . PHE A 1 562 ? 149.104 150.175 128.900 1.00 41.96  ?  551 PHE A CD1 1 
ATOM   4037  C  CD2 . PHE A 1 562 ? 150.359 151.126 130.663 1.00 41.96  ?  551 PHE A CD2 1 
ATOM   4038  C  CE1 . PHE A 1 562 ? 150.232 149.609 128.398 1.00 41.96  ?  551 PHE A CE1 1 
ATOM   4039  C  CE2 . PHE A 1 562 ? 151.491 150.555 130.158 1.00 41.96  ?  551 PHE A CE2 1 
ATOM   4040  C  CZ  . PHE A 1 562 ? 151.425 149.797 129.026 1.00 41.96  ?  551 PHE A CZ  1 
ATOM   4041  N  N   . PHE A 1 563 ? 146.124 152.680 128.227 1.00 42.66  ?  552 PHE A N   1 
ATOM   4042  C  CA  . PHE A 1 563 ? 145.732 152.700 126.825 1.00 42.66  ?  552 PHE A CA  1 
ATOM   4043  C  C   . PHE A 1 563 ? 145.876 154.092 126.230 1.00 42.66  ?  552 PHE A C   1 
ATOM   4044  O  O   . PHE A 1 563 ? 146.377 154.247 125.113 1.00 42.66  ?  552 PHE A O   1 
ATOM   4045  C  CB  . PHE A 1 563 ? 144.296 152.193 126.693 1.00 42.66  ?  552 PHE A CB  1 
ATOM   4046  C  CG  . PHE A 1 563 ? 143.714 152.345 125.322 1.00 42.66  ?  552 PHE A CG  1 
ATOM   4047  C  CD1 . PHE A 1 563 ? 142.902 153.413 125.015 1.00 42.66  ?  552 PHE A CD1 1 
ATOM   4048  C  CD2 . PHE A 1 563 ? 143.965 151.411 124.346 1.00 42.66  ?  552 PHE A CD2 1 
ATOM   4049  C  CE1 . PHE A 1 563 ? 142.372 153.549 123.762 1.00 42.66  ?  552 PHE A CE1 1 
ATOM   4050  C  CE2 . PHE A 1 563 ? 143.433 151.547 123.096 1.00 42.66  ?  552 PHE A CE2 1 
ATOM   4051  C  CZ  . PHE A 1 563 ? 142.637 152.617 122.804 1.00 42.66  ?  552 PHE A CZ  1 
ATOM   4052  N  N   . ARG A 1 564 ? 145.450 155.119 126.963 1.00 47.06  ?  553 ARG A N   1 
ATOM   4053  C  CA  . ARG A 1 564 ? 145.577 156.485 126.470 1.00 47.06  ?  553 ARG A CA  1 
ATOM   4054  C  C   . ARG A 1 564 ? 147.035 156.897 126.339 1.00 47.06  ?  553 ARG A C   1 
ATOM   4055  O  O   . ARG A 1 564 ? 147.426 157.529 125.350 1.00 47.06  ?  553 ARG A O   1 
ATOM   4056  C  CB  . ARG A 1 564 ? 144.833 157.439 127.393 1.00 47.06  ?  553 ARG A CB  1 
ATOM   4057  C  CG  . ARG A 1 564 ? 144.726 158.841 126.857 1.00 47.06  ?  553 ARG A CG  1 
ATOM   4058  C  CD  . ARG A 1 564 ? 144.362 159.829 127.939 1.00 47.06  ?  553 ARG A CD  1 
ATOM   4059  N  NE  . ARG A 1 564 ? 143.565 160.932 127.415 1.00 47.06  ?  553 ARG A NE  1 
ATOM   4060  C  CZ  . ARG A 1 564 ? 142.238 160.978 127.448 1.00 47.06  ?  553 ARG A CZ  1 
ATOM   4061  N  NH1 . ARG A 1 564 ? 141.603 162.021 126.945 1.00 47.06  1  553 ARG A NH1 1 
ATOM   4062  N  NH2 . ARG A 1 564 ? 141.546 159.985 127.986 1.00 47.06  ?  553 ARG A NH2 1 
ATOM   4063  N  N   . ARG A 1 565 ? 147.857 156.551 127.329 1.00 45.31  ?  554 ARG A N   1 
ATOM   4064  C  CA  . ARG A 1 565 ? 149.283 156.841 127.243 1.00 45.31  ?  554 ARG A CA  1 
ATOM   4065  C  C   . ARG A 1 565 ? 149.908 156.190 126.019 1.00 45.31  ?  554 ARG A C   1 
ATOM   4066  O  O   . ARG A 1 565 ? 150.677 156.825 125.290 1.00 45.31  ?  554 ARG A O   1 
ATOM   4067  C  CB  . ARG A 1 565 ? 149.985 156.362 128.506 1.00 45.31  ?  554 ARG A CB  1 
ATOM   4068  C  CG  . ARG A 1 565 ? 150.390 157.453 129.446 1.00 45.31  ?  554 ARG A CG  1 
ATOM   4069  C  CD  . ARG A 1 565 ? 151.030 156.877 130.691 1.00 45.31  ?  554 ARG A CD  1 
ATOM   4070  N  NE  . ARG A 1 565 ? 150.031 156.499 131.684 1.00 45.31  ?  554 ARG A NE  1 
ATOM   4071  C  CZ  . ARG A 1 565 ? 149.971 155.309 132.267 1.00 45.31  ?  554 ARG A CZ  1 
ATOM   4072  N  NH1 . ARG A 1 565 ? 149.026 155.054 133.159 1.00 45.31  1  554 ARG A NH1 1 
ATOM   4073  N  NH2 . ARG A 1 565 ? 150.863 154.379 131.964 1.00 45.31  ?  554 ARG A NH2 1 
ATOM   4074  N  N   . LYS A 1 566 ? 149.583 154.924 125.772 1.00 43.15  ?  555 LYS A N   1 
ATOM   4075  C  CA  . LYS A 1 566 ? 150.180 154.210 124.652 1.00 43.15  ?  555 LYS A CA  1 
ATOM   4076  C  C   . LYS A 1 566 ? 149.685 154.745 123.319 1.00 43.15  ?  555 LYS A C   1 
ATOM   4077  O  O   . LYS A 1 566 ? 150.451 154.820 122.358 1.00 43.15  ?  555 LYS A O   1 
ATOM   4078  C  CB  . LYS A 1 566 ? 149.888 152.722 124.772 1.00 43.15  ?  555 LYS A CB  1 
ATOM   4079  C  CG  . LYS A 1 566 ? 150.616 152.069 125.899 1.00 43.15  ?  555 LYS A CG  1 
ATOM   4080  C  CD  . LYS A 1 566 ? 152.095 152.211 125.723 1.00 43.15  ?  555 LYS A CD  1 
ATOM   4081  C  CE  . LYS A 1 566 ? 152.781 152.392 127.045 1.00 43.15  ?  555 LYS A CE  1 
ATOM   4082  N  NZ  . LYS A 1 566 ? 154.245 152.222 126.909 1.00 43.15  1  555 LYS A NZ  1 
ATOM   4083  N  N   . LEU A 1 567 ? 148.416 155.131 123.239 1.00 43.53  ?  556 LEU A N   1 
ATOM   4084  C  CA  . LEU A 1 567 ? 147.902 155.692 121.998 1.00 43.53  ?  556 LEU A CA  1 
ATOM   4085  C  C   . LEU A 1 567 ? 148.545 157.035 121.696 1.00 43.53  ?  556 LEU A C   1 
ATOM   4086  O  O   . LEU A 1 567 ? 148.856 157.337 120.539 1.00 43.53  ?  556 LEU A O   1 
ATOM   4087  C  CB  . LEU A 1 567 ? 146.386 155.820 122.080 1.00 43.53  ?  556 LEU A CB  1 
ATOM   4088  C  CG  . LEU A 1 567 ? 145.639 156.438 120.905 1.00 43.53  ?  556 LEU A CG  1 
ATOM   4089  C  CD1 . LEU A 1 567 ? 145.905 155.660 119.646 1.00 43.53  ?  556 LEU A CD1 1 
ATOM   4090  C  CD2 . LEU A 1 567 ? 144.169 156.475 121.204 1.00 43.53  ?  556 LEU A CD2 1 
ATOM   4091  N  N   . ILE A 1 568 ? 148.762 157.852 122.725 1.00 44.87  ?  557 ILE A N   1 
ATOM   4092  C  CA  . ILE A 1 568 ? 149.407 159.141 122.516 1.00 44.87  ?  557 ILE A CA  1 
ATOM   4093  C  C   . ILE A 1 568 ? 150.872 158.955 122.143 1.00 44.87  ?  557 ILE A C   1 
ATOM   4094  O  O   . ILE A 1 568 ? 151.427 159.727 121.357 1.00 44.87  ?  557 ILE A O   1 
ATOM   4095  C  CB  . ILE A 1 568 ? 149.219 160.021 123.762 1.00 44.87  ?  557 ILE A CB  1 
ATOM   4096  C  CG1 . ILE A 1 568 ? 147.834 160.655 123.731 1.00 44.87  ?  557 ILE A CG1 1 
ATOM   4097  C  CG2 . ILE A 1 568 ? 150.271 161.091 123.849 1.00 44.87  ?  557 ILE A CG2 1 
ATOM   4098  C  CD1 . ILE A 1 568 ? 147.443 161.301 125.013 1.00 44.87  ?  557 ILE A CD1 1 
ATOM   4099  N  N   . ASP A 1 569 ? 151.517 157.915 122.671 1.00 48.20  ?  558 ASP A N   1 
ATOM   4100  C  CA  . ASP A 1 569 ? 152.878 157.611 122.239 1.00 48.20  ?  558 ASP A CA  1 
ATOM   4101  C  C   . ASP A 1 569 ? 152.907 157.089 120.810 1.00 48.20  ?  558 ASP A C   1 
ATOM   4102  O  O   . ASP A 1 569 ? 153.886 157.295 120.087 1.00 48.20  ?  558 ASP A O   1 
ATOM   4103  C  CB  . ASP A 1 569 ? 153.516 156.597 123.180 1.00 48.20  ?  558 ASP A CB  1 
ATOM   4104  C  CG  . ASP A 1 569 ? 153.782 157.165 124.546 1.00 48.20  ?  558 ASP A CG  1 
ATOM   4105  O  OD1 . ASP A 1 569 ? 153.911 156.372 125.501 1.00 48.20  ?  558 ASP A OD1 1 
ATOM   4106  O  OD2 . ASP A 1 569 ? 153.864 158.404 124.673 1.00 48.20  -1 558 ASP A OD2 1 
ATOM   4107  N  N   . ALA A 1 570 ? 151.851 156.396 120.389 1.00 45.45  ?  559 ALA A N   1 
ATOM   4108  C  CA  . ALA A 1 570 ? 151.820 155.827 119.049 1.00 45.45  ?  559 ALA A CA  1 
ATOM   4109  C  C   . ALA A 1 570 ? 151.578 156.891 117.989 1.00 45.45  ?  559 ALA A C   1 
ATOM   4110  O  O   . ALA A 1 570 ? 152.226 156.876 116.940 1.00 45.45  ?  559 ALA A O   1 
ATOM   4111  C  CB  . ALA A 1 570 ? 150.752 154.742 118.966 1.00 45.45  ?  559 ALA A CB  1 
ATOM   4112  N  N   . VAL A 1 571 ? 150.645 157.813 118.228 1.00 45.46  ?  560 VAL A N   1 
ATOM   4113  C  CA  . VAL A 1 571 ? 150.398 158.833 117.214 1.00 45.46  ?  560 VAL A CA  1 
ATOM   4114  C  C   . VAL A 1 571 ? 151.470 159.911 117.234 1.00 45.46  ?  560 VAL A C   1 
ATOM   4115  O  O   . VAL A 1 571 ? 151.656 160.611 116.236 1.00 45.46  ?  560 VAL A O   1 
ATOM   4116  C  CB  . VAL A 1 571 ? 149.000 159.457 117.356 1.00 45.46  ?  560 VAL A CB  1 
ATOM   4117  C  CG1 . VAL A 1 571 ? 147.941 158.392 117.268 1.00 45.46  ?  560 VAL A CG1 1 
ATOM   4118  C  CG2 . VAL A 1 571 ? 148.878 160.236 118.641 1.00 45.46  ?  560 VAL A CG2 1 
ATOM   4119  N  N   . GLY A 1 572 ? 152.188 160.066 118.340 1.00 46.44  ?  561 GLY A N   1 
ATOM   4120  C  CA  . GLY A 1 572 ? 153.294 160.990 118.413 1.00 46.44  ?  561 GLY A CA  1 
ATOM   4121  C  C   . GLY A 1 572 ? 152.968 162.359 118.957 1.00 46.44  ?  561 GLY A C   1 
ATOM   4122  O  O   . GLY A 1 572 ? 153.853 163.217 118.988 1.00 46.44  ?  561 GLY A O   1 
ATOM   4123  N  N   . PHE A 1 573 ? 151.734 162.596 119.379 1.00 48.44  ?  562 PHE A N   1 
ATOM   4124  C  CA  . PHE A 1 573 ? 151.343 163.876 119.944 1.00 48.44  ?  562 PHE A CA  1 
ATOM   4125  C  C   . PHE A 1 573 ? 150.145 163.645 120.845 1.00 48.44  ?  562 PHE A C   1 
ATOM   4126  O  O   . PHE A 1 573 ? 149.532 162.580 120.833 1.00 48.44  ?  562 PHE A O   1 
ATOM   4127  C  CB  . PHE A 1 573 ? 151.014 164.900 118.854 1.00 48.44  ?  562 PHE A CB  1 
ATOM   4128  C  CG  . PHE A 1 573 ? 149.957 164.445 117.903 1.00 48.44  ?  562 PHE A CG  1 
ATOM   4129  C  CD1 . PHE A 1 573 ? 148.626 164.641 118.183 1.00 48.44  ?  562 PHE A CD1 1 
ATOM   4130  C  CD2 . PHE A 1 573 ? 150.295 163.803 116.736 1.00 48.44  ?  562 PHE A CD2 1 
ATOM   4131  C  CE1 . PHE A 1 573 ? 147.669 164.204 117.325 1.00 48.44  ?  562 PHE A CE1 1 
ATOM   4132  C  CE2 . PHE A 1 573 ? 149.334 163.376 115.875 1.00 48.44  ?  562 PHE A CE2 1 
ATOM   4133  C  CZ  . PHE A 1 573 ? 148.019 163.579 116.167 1.00 48.44  ?  562 PHE A CZ  1 
ATOM   4134  N  N   . SER A 1 574 ? 149.809 164.664 121.623 1.00 50.52  ?  563 SER A N   1 
ATOM   4135  C  CA  . SER A 1 574 ? 148.603 164.648 122.426 1.00 50.52  ?  563 SER A CA  1 
ATOM   4136  C  C   . SER A 1 574 ? 147.553 165.497 121.738 1.00 50.52  ?  563 SER A C   1 
ATOM   4137  O  O   . SER A 1 574 ? 147.794 166.689 121.518 1.00 50.52  ?  563 SER A O   1 
ATOM   4138  C  CB  . SER A 1 574 ? 148.879 165.177 123.824 1.00 50.52  ?  563 SER A CB  1 
ATOM   4139  O  OG  . SER A 1 574 ? 147.694 165.255 124.586 1.00 50.52  ?  563 SER A OG  1 
ATOM   4140  N  N   . PRO A 1 575 ? 146.398 164.944 121.363 1.00 50.92  ?  564 PRO A N   1 
ATOM   4141  C  CA  . PRO A 1 575 ? 145.399 165.748 120.645 1.00 50.92  ?  564 PRO A CA  1 
ATOM   4142  C  C   . PRO A 1 575 ? 144.832 166.902 121.449 1.00 50.92  ?  564 PRO A C   1 
ATOM   4143  O  O   . PRO A 1 575 ? 144.463 167.919 120.852 1.00 50.92  ?  564 PRO A O   1 
ATOM   4144  C  CB  . PRO A 1 575 ? 144.314 164.724 120.286 1.00 50.92  ?  564 PRO A CB  1 
ATOM   4145  C  CG  . PRO A 1 575 ? 144.559 163.574 121.157 1.00 50.92  ?  564 PRO A CG  1 
ATOM   4146  C  CD  . PRO A 1 575 ? 146.014 163.529 121.426 1.00 50.92  ?  564 PRO A CD  1 
ATOM   4147  N  N   . LEU A 1 576 ? 144.754 166.792 122.770 1.00 54.13  ?  565 LEU A N   1 
ATOM   4148  C  CA  . LEU A 1 576 ? 144.292 167.900 123.591 1.00 54.13  ?  565 LEU A CA  1 
ATOM   4149  C  C   . LEU A 1 576 ? 145.287 169.051 123.613 1.00 54.13  ?  565 LEU A C   1 
ATOM   4150  O  O   . LEU A 1 576 ? 144.886 170.216 123.591 1.00 54.13  ?  565 LEU A O   1 
ATOM   4151  C  CB  . LEU A 1 576 ? 144.018 167.415 125.013 1.00 54.13  ?  565 LEU A CB  1 
ATOM   4152  C  CG  . LEU A 1 576 ? 143.312 168.383 125.954 1.00 54.13  ?  565 LEU A CG  1 
ATOM   4153  C  CD1 . LEU A 1 576 ? 142.011 168.860 125.364 1.00 54.13  ?  565 LEU A CD1 1 
ATOM   4154  C  CD2 . LEU A 1 576 ? 143.075 167.711 127.275 1.00 54.13  ?  565 LEU A CD2 1 
ATOM   4155  N  N   . ARG A 1 577 ? 146.581 168.744 123.638 1.00 54.78  ?  566 ARG A N   1 
ATOM   4156  C  CA  . ARG A 1 577 ? 147.593 169.788 123.547 1.00 54.78  ?  566 ARG A CA  1 
ATOM   4157  C  C   . ARG A 1 577 ? 147.514 170.521 122.217 1.00 54.78  ?  566 ARG A C   1 
ATOM   4158  O  O   . ARG A 1 577 ? 147.626 171.751 122.166 1.00 54.78  ?  566 ARG A O   1 
ATOM   4159  C  CB  . ARG A 1 577 ? 148.973 169.176 123.742 1.00 54.78  ?  566 ARG A CB  1 
ATOM   4160  C  CG  . ARG A 1 577 ? 150.079 170.178 123.879 1.00 54.78  ?  566 ARG A CG  1 
ATOM   4161  C  CD  . ARG A 1 577 ? 151.290 169.531 124.479 1.00 54.78  ?  566 ARG A CD  1 
ATOM   4162  N  NE  . ARG A 1 577 ? 150.912 168.604 125.534 1.00 54.78  ?  566 ARG A NE  1 
ATOM   4163  C  CZ  . ARG A 1 577 ? 151.678 167.612 125.965 1.00 54.78  ?  566 ARG A CZ  1 
ATOM   4164  N  NH1 . ARG A 1 577 ? 152.868 167.413 125.425 1.00 54.78  1  566 ARG A NH1 1 
ATOM   4165  N  NH2 . ARG A 1 577 ? 151.253 166.818 126.933 1.00 54.78  ?  566 ARG A NH2 1 
ATOM   4166  N  N   . ILE A 1 578 ? 147.314 169.780 121.128 1.00 55.34  ?  567 ILE A N   1 
ATOM   4167  C  CA  . ILE A 1 578 ? 147.181 170.398 119.816 1.00 55.34  ?  567 ILE A CA  1 
ATOM   4168  C  C   . ILE A 1 578 ? 145.939 171.270 119.761 1.00 55.34  ?  567 ILE A C   1 
ATOM   4169  O  O   . ILE A 1 578 ? 145.966 172.375 119.212 1.00 55.34  ?  567 ILE A O   1 
ATOM   4170  C  CB  . ILE A 1 578 ? 147.162 169.320 118.717 1.00 55.34  ?  567 ILE A CB  1 
ATOM   4171  C  CG1 . ILE A 1 578 ? 148.395 168.433 118.817 1.00 55.34  ?  567 ILE A CG1 1 
ATOM   4172  C  CG2 . ILE A 1 578 ? 147.100 169.962 117.356 1.00 55.34  ?  567 ILE A CG2 1 
ATOM   4173  C  CD1 . ILE A 1 578 ? 149.639 169.082 118.324 1.00 55.34  ?  567 ILE A CD1 1 
ATOM   4174  N  N   . LEU A 1 579 ? 144.832 170.791 120.325 1.00 56.10  ?  568 LEU A N   1 
ATOM   4175  C  CA  . LEU A 1 579 ? 143.613 171.587 120.325 1.00 56.10  ?  568 LEU A CA  1 
ATOM   4176  C  C   . LEU A 1 579 ? 143.784 172.865 121.129 1.00 56.10  ?  568 LEU A C   1 
ATOM   4177  O  O   . LEU A 1 579 ? 143.301 173.925 120.725 1.00 56.10  ?  568 LEU A O   1 
ATOM   4178  C  CB  . LEU A 1 579 ? 142.454 170.769 120.871 1.00 56.10  ?  568 LEU A CB  1 
ATOM   4179  C  CG  . LEU A 1 579 ? 141.148 171.532 121.035 1.00 56.10  ?  568 LEU A CG  1 
ATOM   4180  C  CD1 . LEU A 1 579 ? 140.534 171.846 119.694 1.00 56.10  ?  568 LEU A CD1 1 
ATOM   4181  C  CD2 . LEU A 1 579 ? 140.205 170.741 121.888 1.00 56.10  ?  568 LEU A CD2 1 
ATOM   4182  N  N   . ARG A 1 580 ? 144.481 172.790 122.261 1.00 57.00  ?  569 ARG A N   1 
ATOM   4183  C  CA  . ARG A 1 580 ? 144.685 173.979 123.077 1.00 57.00  ?  569 ARG A CA  1 
ATOM   4184  C  C   . ARG A 1 580 ? 145.588 174.982 122.379 1.00 57.00  ?  569 ARG A C   1 
ATOM   4185  O  O   . ARG A 1 580 ? 145.335 176.189 122.430 1.00 57.00  ?  569 ARG A O   1 
ATOM   4186  C  CB  . ARG A 1 580 ? 145.259 173.589 124.432 1.00 57.00  ?  569 ARG A CB  1 
ATOM   4187  C  CG  . ARG A 1 580 ? 144.244 172.964 125.336 1.00 57.00  ?  569 ARG A CG  1 
ATOM   4188  C  CD  . ARG A 1 580 ? 144.882 172.332 126.529 1.00 57.00  ?  569 ARG A CD  1 
ATOM   4189  N  NE  . ARG A 1 580 ? 143.871 171.860 127.460 1.00 57.00  ?  569 ARG A NE  1 
ATOM   4190  C  CZ  . ARG A 1 580 ? 144.118 171.062 128.486 1.00 57.00  ?  569 ARG A CZ  1 
ATOM   4191  N  NH1 . ARG A 1 580 ? 145.348 170.645 128.716 1.00 57.00  1  569 ARG A NH1 1 
ATOM   4192  N  NH2 . ARG A 1 580 ? 143.135 170.679 129.279 1.00 57.00  ?  569 ARG A NH2 1 
ATOM   4193  N  N   . LYS A 1 581 ? 146.638 174.508 121.711 1.00 59.48  ?  570 LYS A N   1 
ATOM   4194  C  CA  . LYS A 1 581 ? 147.499 175.428 120.979 1.00 59.48  ?  570 LYS A CA  1 
ATOM   4195  C  C   . LYS A 1 581 ? 146.784 176.045 119.786 1.00 59.48  ?  570 LYS A C   1 
ATOM   4196  O  O   . LYS A 1 581 ? 146.996 177.222 119.480 1.00 59.48  ?  570 LYS A O   1 
ATOM   4197  C  CB  . LYS A 1 581 ? 148.772 174.716 120.550 1.00 59.48  ?  570 LYS A CB  1 
ATOM   4198  C  CG  . LYS A 1 581 ? 149.814 174.709 121.634 1.00 59.48  ?  570 LYS A CG  1 
ATOM   4199  C  CD  . LYS A 1 581 ? 150.847 173.643 121.424 1.00 59.48  ?  570 LYS A CD  1 
ATOM   4200  C  CE  . LYS A 1 581 ? 151.911 173.708 122.501 1.00 59.48  ?  570 LYS A CE  1 
ATOM   4201  N  NZ  . LYS A 1 581 ? 152.830 172.541 122.445 1.00 59.48  1  570 LYS A NZ  1 
ATOM   4202  N  N   . ARG A 1 582 ? 145.905 175.294 119.127 1.00 60.77  ?  571 ARG A N   1 
ATOM   4203  C  CA  . ARG A 1 582 ? 145.129 175.873 118.038 1.00 60.77  ?  571 ARG A CA  1 
ATOM   4204  C  C   . ARG A 1 582 ? 144.116 176.881 118.549 1.00 60.77  ?  571 ARG A C   1 
ATOM   4205  O  O   . ARG A 1 582 ? 143.839 177.877 117.880 1.00 60.77  ?  571 ARG A O   1 
ATOM   4206  C  CB  . ARG A 1 582 ? 144.424 174.780 117.257 1.00 60.77  ?  571 ARG A CB  1 
ATOM   4207  C  CG  . ARG A 1 582 ? 145.328 173.958 116.420 1.00 60.77  ?  571 ARG A CG  1 
ATOM   4208  C  CD  . ARG A 1 582 ? 144.540 172.873 115.803 1.00 60.77  ?  571 ARG A CD  1 
ATOM   4209  N  NE  . ARG A 1 582 ? 145.372 171.976 115.031 1.00 60.77  ?  571 ARG A NE  1 
ATOM   4210  C  CZ  . ARG A 1 582 ? 144.882 171.077 114.200 1.00 60.77  ?  571 ARG A CZ  1 
ATOM   4211  N  NH1 . ARG A 1 582 ? 143.578 170.985 114.054 1.00 60.77  1  571 ARG A NH1 1 
ATOM   4212  N  NH2 . ARG A 1 582 ? 145.688 170.287 113.526 1.00 60.77  ?  571 ARG A NH2 1 
ATOM   4213  N  N   . ASN A 1 583 ? 143.530 176.641 119.710 1.00 62.20  ?  572 ASN A N   1 
ATOM   4214  C  CA  . ASN A 1 583 ? 142.519 177.550 120.219 1.00 62.20  ?  572 ASN A CA  1 
ATOM   4215  C  C   . ASN A 1 583 ? 143.176 178.860 120.610 1.00 62.20  ?  572 ASN A C   1 
ATOM   4216  O  O   . ASN A 1 583 ? 142.599 179.925 120.412 1.00 62.20  ?  572 ASN A O   1 
ATOM   4217  C  CB  . ASN A 1 583 ? 141.769 176.937 121.394 1.00 62.20  ?  572 ASN A CB  1 
ATOM   4218  C  CG  . ASN A 1 583 ? 140.493 176.244 120.974 1.00 62.20  ?  572 ASN A CG  1 
ATOM   4219  O  OD1 . ASN A 1 583 ? 139.720 176.776 120.181 1.00 62.20  ?  572 ASN A OD1 1 
ATOM   4220  N  ND2 . ASN A 1 583 ? 140.255 175.058 121.517 1.00 62.20  ?  572 ASN A ND2 1 
ATOM   4221  N  N   . LYS A 1 584 ? 144.390 178.792 121.143 1.00 65.56  ?  573 LYS A N   1 
ATOM   4222  C  CA  . LYS A 1 584 ? 145.115 180.006 121.485 1.00 65.56  ?  573 LYS A CA  1 
ATOM   4223  C  C   . LYS A 1 584 ? 145.445 180.810 120.249 1.00 65.56  ?  573 LYS A C   1 
ATOM   4224  O  O   . LYS A 1 584 ? 145.279 182.025 120.228 1.00 65.56  ?  573 LYS A O   1 
ATOM   4225  C  CB  . LYS A 1 584 ? 146.407 179.674 122.222 1.00 65.56  ?  573 LYS A CB  1 
ATOM   4226  C  CG  . LYS A 1 584 ? 146.206 179.128 123.622 1.00 65.56  ?  573 LYS A CG  1 
ATOM   4227  C  CD  . LYS A 1 584 ? 147.535 178.957 124.337 1.00 65.56  ?  573 LYS A CD  1 
ATOM   4228  C  CE  . LYS A 1 584 ? 148.341 177.812 123.748 1.00 65.56  ?  573 LYS A CE  1 
ATOM   4229  N  NZ  . LYS A 1 584 ? 147.744 176.490 124.080 1.00 65.56  1  573 LYS A NZ  1 
ATOM   4230  N  N   . ALA A 1 585 ? 145.922 180.136 119.215 1.00 70.85  ?  574 ALA A N   1 
ATOM   4231  C  CA  . ALA A 1 585 ? 146.277 180.815 117.985 1.00 70.85  ?  574 ALA A CA  1 
ATOM   4232  C  C   . ALA A 1 585 ? 145.056 181.470 117.388 1.00 70.85  ?  574 ALA A C   1 
ATOM   4233  O  O   . ALA A 1 585 ? 145.122 182.598 116.917 1.00 70.85  ?  574 ALA A O   1 
ATOM   4234  C  CB  . ALA A 1 585 ? 146.884 179.830 117.010 1.00 70.85  ?  574 ALA A CB  1 
ATOM   4235  N  N   . LEU A 1 586 ? 143.933 180.773 117.419 1.00 75.47  ?  575 LEU A N   1 
ATOM   4236  C  CA  . LEU A 1 586 ? 142.700 181.331 116.893 1.00 75.47  ?  575 LEU A CA  1 
ATOM   4237  C  C   . LEU A 1 586 ? 142.344 182.597 117.641 1.00 75.47  ?  575 LEU A C   1 
ATOM   4238  O  O   . LEU A 1 586 ? 141.871 183.560 117.047 1.00 75.47  ?  575 LEU A O   1 
ATOM   4239  C  CB  . LEU A 1 586 ? 141.567 180.317 117.004 1.00 75.47  ?  575 LEU A CB  1 
ATOM   4240  C  CG  . LEU A 1 586 ? 140.227 180.710 116.387 1.00 75.47  ?  575 LEU A CG  1 
ATOM   4241  C  CD1 . LEU A 1 586 ? 140.406 181.129 114.937 1.00 75.47  ?  575 LEU A CD1 1 
ATOM   4242  C  CD2 . LEU A 1 586 ? 139.243 179.559 116.500 1.00 75.47  ?  575 LEU A CD2 1 
ATOM   4243  N  N   . ARG A 1 587 ? 142.571 182.604 118.947 1.00 78.73  ?  576 ARG A N   1 
ATOM   4244  C  CA  . ARG A 1 587 ? 142.295 183.789 119.752 1.00 78.73  ?  576 ARG A CA  1 
ATOM   4245  C  C   . ARG A 1 587 ? 143.162 184.971 119.343 1.00 78.73  ?  576 ARG A C   1 
ATOM   4246  O  O   . ARG A 1 587 ? 142.664 186.079 119.180 1.00 78.73  ?  576 ARG A O   1 
ATOM   4247  C  CB  . ARG A 1 587 ? 142.513 183.491 121.230 1.00 78.73  ?  576 ARG A CB  1 
ATOM   4248  C  CG  . ARG A 1 587 ? 141.434 182.627 121.853 1.00 78.73  ?  576 ARG A CG  1 
ATOM   4249  C  CD  . ARG A 1 587 ? 141.712 182.390 123.325 1.00 78.73  ?  576 ARG A CD  1 
ATOM   4250  N  NE  . ARG A 1 587 ? 140.476 182.312 124.093 1.00 78.73  ?  576 ARG A NE  1 
ATOM   4251  C  CZ  . ARG A 1 587 ? 139.897 183.352 124.683 1.00 78.73  ?  576 ARG A CZ  1 
ATOM   4252  N  NH1 . ARG A 1 587 ? 140.445 184.555 124.601 1.00 78.73  1  576 ARG A NH1 1 
ATOM   4253  N  NH2 . ARG A 1 587 ? 138.769 183.189 125.358 1.00 78.73  ?  576 ARG A NH2 1 
ATOM   4254  N  N   . LYS A 1 588 ? 144.456 184.742 119.181 1.00 83.34  ?  577 LYS A N   1 
ATOM   4255  C  CA  . LYS A 1 588 ? 145.342 185.815 118.764 1.00 83.34  ?  577 LYS A CA  1 
ATOM   4256  C  C   . LYS A 1 588 ? 144.935 186.318 117.398 1.00 83.34  ?  577 LYS A C   1 
ATOM   4257  O  O   . LYS A 1 588 ? 144.964 187.515 117.137 1.00 83.34  ?  577 LYS A O   1 
ATOM   4258  C  CB  . LYS A 1 588 ? 146.788 185.345 118.727 1.00 83.34  ?  577 LYS A CB  1 
ATOM   4259  C  CG  . LYS A 1 588 ? 147.758 186.397 118.222 1.00 83.34  ?  577 LYS A CG  1 
ATOM   4260  C  CD  . LYS A 1 588 ? 149.174 185.855 118.167 1.00 83.34  ?  577 LYS A CD  1 
ATOM   4261  C  CE  . LYS A 1 588 ? 149.625 185.360 119.530 1.00 83.34  ?  577 LYS A CE  1 
ATOM   4262  N  NZ  . LYS A 1 588 ? 151.006 184.807 119.486 1.00 83.34  1  577 LYS A NZ  1 
ATOM   4263  N  N   . ILE A 1 589 ? 144.562 185.401 116.518 1.00 86.69  ?  578 ILE A N   1 
ATOM   4264  C  CA  . ILE A 1 589 ? 144.170 185.785 115.179 1.00 86.69  ?  578 ILE A CA  1 
ATOM   4265  C  C   . ILE A 1 589 ? 142.955 186.675 115.260 1.00 86.69  ?  578 ILE A C   1 
ATOM   4266  O  O   . ILE A 1 589 ? 142.901 187.715 114.617 1.00 86.69  ?  578 ILE A O   1 
ATOM   4267  C  CB  . ILE A 1 589 ? 143.848 184.554 114.313 1.00 86.69  ?  578 ILE A CB  1 
ATOM   4268  C  CG1 . ILE A 1 589 ? 145.118 183.753 114.030 1.00 86.69  ?  578 ILE A CG1 1 
ATOM   4269  C  CG2 . ILE A 1 589 ? 143.189 184.972 113.009 1.00 86.69  ?  578 ILE A CG2 1 
ATOM   4270  C  CD1 . ILE A 1 589 ? 144.871 182.480 113.252 1.00 86.69  ?  578 ILE A CD1 1 
ATOM   4271  N  N   . ARG A 1 590 ? 141.980 186.276 116.061 1.00 89.55  ?  579 ARG A N   1 
ATOM   4272  C  CA  . ARG A 1 590 ? 140.770 187.068 116.209 1.00 89.55  ?  579 ARG A CA  1 
ATOM   4273  C  C   . ARG A 1 590 ? 141.104 188.411 116.830 1.00 89.55  ?  579 ARG A C   1 
ATOM   4274  O  O   . ARG A 1 590 ? 140.525 189.430 116.465 1.00 89.55  ?  579 ARG A O   1 
ATOM   4275  C  CB  . ARG A 1 590 ? 139.737 186.305 117.033 1.00 89.55  ?  579 ARG A CB  1 
ATOM   4276  C  CG  . ARG A 1 590 ? 139.125 185.145 116.268 1.00 89.55  ?  579 ARG A CG  1 
ATOM   4277  C  CD  . ARG A 1 590 ? 138.313 184.220 117.157 1.00 89.55  ?  579 ARG A CD  1 
ATOM   4278  N  NE  . ARG A 1 590 ? 137.625 183.202 116.367 1.00 89.55  ?  579 ARG A NE  1 
ATOM   4279  C  CZ  . ARG A 1 590 ? 136.929 182.196 116.883 1.00 89.55  ?  579 ARG A CZ  1 
ATOM   4280  N  NH1 . ARG A 1 590 ? 136.832 182.060 118.198 1.00 89.55  1  579 ARG A NH1 1 
ATOM   4281  N  NH2 . ARG A 1 590 ? 136.334 181.320 116.085 1.00 89.55  ?  579 ARG A NH2 1 
ATOM   4282  N  N   . LYS A 1 591 ? 142.045 188.421 117.760 1.00 94.60  ?  580 LYS A N   1 
ATOM   4283  C  CA  . LYS A 1 591 ? 142.465 189.670 118.368 1.00 94.60  ?  580 LYS A CA  1 
ATOM   4284  C  C   . LYS A 1 591 ? 143.061 190.595 117.324 1.00 94.60  ?  580 LYS A C   1 
ATOM   4285  O  O   . LYS A 1 591 ? 142.647 191.746 117.202 1.00 94.60  ?  580 LYS A O   1 
ATOM   4286  C  CB  . LYS A 1 591 ? 143.491 189.401 119.463 1.00 94.60  ?  580 LYS A CB  1 
ATOM   4287  C  CG  . LYS A 1 591 ? 144.416 190.570 119.746 1.00 94.60  ?  580 LYS A CG  1 
ATOM   4288  C  CD  . LYS A 1 591 ? 145.545 190.158 120.674 1.00 94.60  ?  580 LYS A CD  1 
ATOM   4289  C  CE  . LYS A 1 591 ? 146.567 191.272 120.813 1.00 94.60  ?  580 LYS A CE  1 
ATOM   4290  N  NZ  . LYS A 1 591 ? 147.141 191.644 119.491 1.00 94.60  1  580 LYS A NZ  1 
ATOM   4291  N  N   . LEU A 1 592 ? 144.020 190.095 116.556 1.00 97.53  ?  581 LEU A N   1 
ATOM   4292  C  CA  . LEU A 1 592 ? 144.651 190.905 115.527 1.00 97.53  ?  581 LEU A CA  1 
ATOM   4293  C  C   . LEU A 1 592 ? 143.633 191.292 114.479 1.00 97.53  ?  581 LEU A C   1 
ATOM   4294  O  O   . LEU A 1 592 ? 143.701 192.378 113.911 1.00 97.53  ?  581 LEU A O   1 
ATOM   4295  C  CB  . LEU A 1 592 ? 145.800 190.138 114.880 1.00 97.53  ?  581 LEU A CB  1 
ATOM   4296  C  CG  . LEU A 1 592 ? 146.937 189.734 115.816 1.00 97.53  ?  581 LEU A CG  1 
ATOM   4297  C  CD1 . LEU A 1 592 ? 147.860 188.732 115.142 1.00 97.53  ?  581 LEU A CD1 1 
ATOM   4298  C  CD2 . LEU A 1 592 ? 147.704 190.961 116.282 1.00 97.53  ?  581 LEU A CD2 1 
ATOM   4299  N  N   . GLN A 1 593 ? 142.689 190.403 114.214 1.00 99.74  ?  582 GLN A N   1 
ATOM   4300  C  CA  . GLN A 1 593 ? 141.660 190.685 113.230 1.00 99.74  ?  582 GLN A CA  1 
ATOM   4301  C  C   . GLN A 1 593 ? 140.811 191.857 113.663 1.00 99.74  ?  582 GLN A C   1 
ATOM   4302  O  O   . GLN A 1 593 ? 140.497 192.731 112.860 1.00 99.74  ?  582 GLN A O   1 
ATOM   4303  C  CB  . GLN A 1 593 ? 140.766 189.463 113.030 1.00 99.74  ?  582 GLN A CB  1 
ATOM   4304  C  CG  . GLN A 1 593 ? 139.608 189.693 112.078 1.00 99.74  ?  582 GLN A CG  1 
ATOM   4305  C  CD  . GLN A 1 593 ? 138.633 188.536 112.067 1.00 99.74  ?  582 GLN A CD  1 
ATOM   4306  O  OE1 . GLN A 1 593 ? 138.693 187.652 112.922 1.00 99.74  ?  582 GLN A OE1 1 
ATOM   4307  N  NE2 . GLN A 1 593 ? 137.723 188.537 111.100 1.00 99.74  ?  582 GLN A NE2 1 
ATOM   4308  N  N   . LYS A 1 594 ? 140.442 191.885 114.935 1.00 100.55 ?  583 LYS A N   1 
ATOM   4309  C  CA  . LYS A 1 594 ? 139.607 192.961 115.435 1.00 100.55 ?  583 LYS A CA  1 
ATOM   4310  C  C   . LYS A 1 594 ? 140.419 194.242 115.524 1.00 100.55 ?  583 LYS A C   1 
ATOM   4311  O  O   . LYS A 1 594 ? 139.922 195.319 115.199 1.00 100.55 ?  583 LYS A O   1 
ATOM   4312  C  CB  . LYS A 1 594 ? 139.027 192.594 116.798 1.00 100.55 ?  583 LYS A CB  1 
ATOM   4313  C  CG  . LYS A 1 594 ? 137.918 193.520 117.264 1.00 100.55 ?  583 LYS A CG  1 
ATOM   4314  C  CD  . LYS A 1 594 ? 137.362 193.080 118.607 1.00 100.55 ?  583 LYS A CD  1 
ATOM   4315  C  CE  . LYS A 1 594 ? 136.166 193.929 119.005 1.00 100.55 ?  583 LYS A CE  1 
ATOM   4316  N  NZ  . LYS A 1 594 ? 136.500 195.379 119.028 1.00 100.55 1  583 LYS A NZ  1 
ATOM   4317  N  N   . GLN A 1 595 ? 141.668 194.131 115.959 1.00 103.04 ?  584 GLN A N   1 
ATOM   4318  C  CA  . GLN A 1 595 ? 142.532 195.299 116.028 1.00 103.04 ?  584 GLN A CA  1 
ATOM   4319  C  C   . GLN A 1 595 ? 142.734 195.900 114.646 1.00 103.04 ?  584 GLN A C   1 
ATOM   4320  O  O   . GLN A 1 595 ? 142.661 197.116 114.479 1.00 103.04 ?  584 GLN A O   1 
ATOM   4321  C  CB  . GLN A 1 595 ? 143.882 194.930 116.629 1.00 103.04 ?  584 GLN A CB  1 
ATOM   4322  C  CG  . GLN A 1 595 ? 143.829 194.552 118.096 1.00 103.04 ?  584 GLN A CG  1 
ATOM   4323  C  CD  . GLN A 1 595 ? 145.158 194.031 118.598 1.00 103.04 ?  584 GLN A CD  1 
ATOM   4324  O  OE1 . GLN A 1 595 ? 145.398 193.966 119.803 1.00 103.04 ?  584 GLN A OE1 1 
ATOM   4325  N  NE2 . GLN A 1 595 ? 146.035 193.662 117.672 1.00 103.04 ?  584 GLN A NE2 1 
ATOM   4326  N  N   . GLY A 1 596 ? 142.983 195.055 113.651 1.00 107.86 ?  585 GLY A N   1 
ATOM   4327  C  CA  . GLY A 1 596 ? 143.156 195.535 112.291 1.00 107.86 ?  585 GLY A CA  1 
ATOM   4328  C  C   . GLY A 1 596 ? 144.432 195.060 111.634 1.00 107.86 ?  585 GLY A C   1 
ATOM   4329  O  O   . GLY A 1 596 ? 144.533 195.048 110.408 1.00 107.86 ?  585 GLY A O   1 
ATOM   4330  N  N   . LEU A 1 597 ? 145.404 194.646 112.437 1.00 110.14 ?  586 LEU A N   1 
ATOM   4331  C  CA  . LEU A 1 597 ? 146.680 194.189 111.902 1.00 110.14 ?  586 LEU A CA  1 
ATOM   4332  C  C   . LEU A 1 597 ? 146.483 193.028 110.937 1.00 110.14 ?  586 LEU A C   1 
ATOM   4333  O  O   . LEU A 1 597 ? 147.342 192.764 110.095 1.00 110.14 ?  586 LEU A O   1 
ATOM   4334  C  CB  . LEU A 1 597 ? 147.614 193.772 113.037 1.00 110.14 ?  586 LEU A CB  1 
ATOM   4335  C  CG  . LEU A 1 597 ? 148.045 194.831 114.057 1.00 110.14 ?  586 LEU A CG  1 
ATOM   4336  C  CD1 . LEU A 1 597 ? 146.874 195.326 114.892 1.00 110.14 ?  586 LEU A CD1 1 
ATOM   4337  C  CD2 . LEU A 1 597 ? 149.140 194.286 114.960 1.00 110.14 ?  586 LEU A CD2 1 
ATOM   4338  N  N   . LEU A 1 598 ? 145.363 192.327 111.061 1.00 108.64 ?  587 LEU A N   1 
ATOM   4339  C  CA  . LEU A 1 598 ? 145.069 191.214 110.167 1.00 108.64 ?  587 LEU A CA  1 
ATOM   4340  C  C   . LEU A 1 598 ? 143.721 191.421 109.504 1.00 108.64 ?  587 LEU A C   1 
ATOM   4341  O  O   . LEU A 1 598 ? 142.751 191.795 110.163 1.00 108.64 ?  587 LEU A O   1 
ATOM   4342  C  CB  . LEU A 1 598 ? 145.074 189.895 110.936 1.00 108.64 ?  587 LEU A CB  1 
ATOM   4343  C  CG  . LEU A 1 598 ? 144.501 188.678 110.212 1.00 108.64 ?  587 LEU A CG  1 
ATOM   4344  C  CD1 . LEU A 1 598 ? 145.284 188.389 108.943 1.00 108.64 ?  587 LEU A CD1 1 
ATOM   4345  C  CD2 . LEU A 1 598 ? 144.514 187.472 111.135 1.00 108.64 ?  587 LEU A CD2 1 
ATOM   4346  N  N   . GLN A 1 599 ? 143.653 191.184 108.200 1.00 115.35 ?  588 GLN A N   1 
ATOM   4347  C  CA  . GLN A 1 599 ? 142.402 191.370 107.480 1.00 115.35 ?  588 GLN A CA  1 
ATOM   4348  C  C   . GLN A 1 599 ? 141.947 190.089 106.807 1.00 115.35 ?  588 GLN A C   1 
ATOM   4349  O  O   . GLN A 1 599 ? 142.691 189.487 106.037 1.00 115.35 ?  588 GLN A O   1 
ATOM   4350  C  CB  . GLN A 1 599 ? 142.544 192.485 106.447 1.00 115.35 ?  588 GLN A CB  1 
ATOM   4351  C  CG  . GLN A 1 599 ? 142.810 193.852 107.052 1.00 115.35 ?  588 GLN A CG  1 
ATOM   4352  C  CD  . GLN A 1 599 ? 143.092 194.907 106.002 1.00 115.35 ?  588 GLN A CD  1 
ATOM   4353  O  OE1 . GLN A 1 599 ? 143.059 194.631 104.803 1.00 115.35 ?  588 GLN A OE1 1 
ATOM   4354  N  NE2 . GLN A 1 599 ? 143.377 196.124 106.449 1.00 115.35 ?  588 GLN A NE2 1 
ATOM   4355  N  N   . VAL A 1 600 ? 140.720 189.674 107.095 1.00 116.17 ?  589 VAL A N   1 
ATOM   4356  C  CA  . VAL A 1 600 ? 140.202 188.439 106.523 1.00 116.17 ?  589 VAL A CA  1 
ATOM   4357  C  C   . VAL A 1 600 ? 139.987 188.588 105.024 1.00 116.17 ?  589 VAL A C   1 
ATOM   4358  O  O   . VAL A 1 600 ? 139.747 189.690 104.534 1.00 116.17 ?  589 VAL A O   1 
ATOM   4359  C  CB  . VAL A 1 600 ? 138.891 188.013 107.205 1.00 116.17 ?  589 VAL A CB  1 
ATOM   4360  C  CG1 . VAL A 1 600 ? 137.734 188.874 106.724 1.00 116.17 ?  589 VAL A CG1 1 
ATOM   4361  C  CG2 . VAL A 1 600 ? 138.617 186.543 106.942 1.00 116.17 ?  589 VAL A CG2 1 
ATOM   4362  N  N   . THR A 1 601 ? 140.077 187.487 104.290 1.00 118.14 ?  590 THR A N   1 
ATOM   4363  C  CA  . THR A 1 601 ? 139.957 187.557 102.843 1.00 118.14 ?  590 THR A CA  1 
ATOM   4364  C  C   . THR A 1 601 ? 139.573 186.205 102.281 1.00 118.14 ?  590 THR A C   1 
ATOM   4365  O  O   . THR A 1 601 ? 140.045 185.175 102.762 1.00 118.14 ?  590 THR A O   1 
ATOM   4366  C  CB  . THR A 1 601 ? 141.290 187.999 102.212 1.00 118.14 ?  590 THR A CB  1 
ATOM   4367  O  OG1 . THR A 1 601 ? 141.629 189.311 102.677 1.00 118.14 ?  590 THR A OG1 1 
ATOM   4368  C  CG2 . THR A 1 601 ? 141.199 188.017 100.693 1.00 118.14 ?  590 THR A CG2 1 
ATOM   4369  N  N   . PRO A 1 602 ? 138.721 186.194 101.249 1.00 118.10 ?  591 PRO A N   1 
ATOM   4370  C  CA  . PRO A 1 602 ? 138.404 184.914 100.623 1.00 118.10 ?  591 PRO A CA  1 
ATOM   4371  C  C   . PRO A 1 602 ? 139.688 184.146 100.425 1.00 118.10 ?  591 PRO A C   1 
ATOM   4372  O  O   . PRO A 1 602 ? 139.721 182.937 100.652 1.00 118.10 ?  591 PRO A O   1 
ATOM   4373  C  CB  . PRO A 1 602 ? 137.832 185.330 99.276  1.00 118.10 ?  591 PRO A CB  1 
ATOM   4374  C  CG  . PRO A 1 602 ? 137.208 186.663 99.530  1.00 118.10 ?  591 PRO A CG  1 
ATOM   4375  C  CD  . PRO A 1 602 ? 137.938 187.304 100.680 1.00 118.10 ?  591 PRO A CD  1 
ATOM   4376  N  N   . LYS A 1 603 ? 140.742 184.837 100.007 1.00 118.93 ?  592 LYS A N   1 
ATOM   4377  C  CA  . LYS A 1 603 ? 142.034 184.196 99.861  1.00 118.93 ?  592 LYS A CA  1 
ATOM   4378  C  C   . LYS A 1 603 ? 142.822 184.349 101.145 1.00 118.93 ?  592 LYS A C   1 
ATOM   4379  O  O   . LYS A 1 603 ? 143.499 185.359 101.340 1.00 118.93 ?  592 LYS A O   1 
ATOM   4380  C  CB  . LYS A 1 603 ? 142.809 184.816 98.707  1.00 118.93 ?  592 LYS A CB  1 
ATOM   4381  C  CG  . LYS A 1 603 ? 142.194 184.552 97.342  1.00 118.93 ?  592 LYS A CG  1 
ATOM   4382  C  CD  . LYS A 1 603 ? 142.993 185.214 96.232  1.00 118.93 ?  592 LYS A CD  1 
ATOM   4383  C  CE  . LYS A 1 603 ? 142.394 184.932 94.860  1.00 118.93 ?  592 LYS A CE  1 
ATOM   4384  N  NZ  . LYS A 1 603 ? 143.132 185.581 93.740  1.00 118.93 1  592 LYS A NZ  1 
ATOM   4385  N  N   . GLY A 1 604 ? 142.726 183.368 102.035 1.00 116.29 ?  593 GLY A N   1 
ATOM   4386  C  CA  . GLY A 1 604 ? 143.503 183.402 103.263 1.00 116.29 ?  593 GLY A CA  1 
ATOM   4387  C  C   . GLY A 1 604 ? 143.418 184.664 104.090 1.00 116.29 ?  593 GLY A C   1 
ATOM   4388  O  O   . GLY A 1 604 ? 142.328 185.185 104.321 1.00 116.29 ?  593 GLY A O   1 
ATOM   4389  N  N   . PHE A 1 605 ? 144.564 185.176 104.532 1.00 112.92 ?  594 PHE A N   1 
ATOM   4390  C  CA  . PHE A 1 605 ? 144.564 186.342 105.415 1.00 112.92 ?  594 PHE A CA  1 
ATOM   4391  C  C   . PHE A 1 605 ? 145.441 187.490 104.943 1.00 112.92 ?  594 PHE A C   1 
ATOM   4392  O  O   . PHE A 1 605 ? 146.301 187.308 104.083 1.00 112.92 ?  594 PHE A O   1 
ATOM   4393  C  CB  . PHE A 1 605 ? 145.019 185.922 106.815 1.00 112.92 ?  594 PHE A CB  1 
ATOM   4394  C  CG  . PHE A 1 605 ? 143.895 185.519 107.724 1.00 112.92 ?  594 PHE A CG  1 
ATOM   4395  C  CD1 . PHE A 1 605 ? 142.759 186.305 107.831 1.00 112.92 ?  594 PHE A CD1 1 
ATOM   4396  C  CD2 . PHE A 1 605 ? 143.983 184.370 108.490 1.00 112.92 ?  594 PHE A CD2 1 
ATOM   4397  C  CE1 . PHE A 1 605 ? 141.725 185.943 108.673 1.00 112.92 ?  594 PHE A CE1 1 
ATOM   4398  C  CE2 . PHE A 1 605 ? 142.954 184.003 109.336 1.00 112.92 ?  594 PHE A CE2 1 
ATOM   4399  C  CZ  . PHE A 1 605 ? 141.823 184.790 109.427 1.00 112.92 ?  594 PHE A CZ  1 
ATOM   4400  N  N   . ILE A 1 606 ? 145.229 188.675 105.509 1.00 115.79 ?  595 ILE A N   1 
ATOM   4401  C  CA  . ILE A 1 606 ? 146.039 189.833 105.151 1.00 115.79 ?  595 ILE A CA  1 
ATOM   4402  C  C   . ILE A 1 606 ? 146.899 190.291 106.319 1.00 115.79 ?  595 ILE A C   1 
ATOM   4403  O  O   . ILE A 1 606 ? 146.380 190.813 107.305 1.00 115.79 ?  595 ILE A O   1 
ATOM   4404  C  CB  . ILE A 1 606 ? 145.160 191.016 104.714 1.00 115.79 ?  595 ILE A CB  1 
ATOM   4405  C  CG1 . ILE A 1 606 ? 144.391 190.669 103.441 1.00 115.79 ?  595 ILE A CG1 1 
ATOM   4406  C  CG2 . ILE A 1 606 ? 146.008 192.260 104.499 1.00 115.79 ?  595 ILE A CG2 1 
ATOM   4407  C  CD1 . ILE A 1 606 ? 143.529 191.803 102.932 1.00 115.79 ?  595 ILE A CD1 1 
ATOM   4408  N  N   . CYS A 1 607 ? 148.211 190.109 106.212 1.00 118.09 ?  596 CYS A N   1 
ATOM   4409  C  CA  . CYS A 1 607 ? 149.113 190.570 107.263 1.00 118.09 ?  596 CYS A CA  1 
ATOM   4410  C  C   . CYS A 1 607 ? 149.279 192.074 107.171 1.00 118.09 ?  596 CYS A C   1 
ATOM   4411  O  O   . CYS A 1 607 ? 150.389 192.569 106.984 1.00 118.09 ?  596 CYS A O   1 
ATOM   4412  C  CB  . CYS A 1 607 ? 150.474 189.888 107.147 1.00 118.09 ?  596 CYS A CB  1 
ATOM   4413  S  SG  . CYS A 1 607 ? 150.413 188.083 107.213 1.00 118.09 ?  596 CYS A SG  1 
ATOM   4414  N  N   . THR A 1 608 ? 148.182 192.809 107.301 1.00 118.01 ?  597 THR A N   1 
ATOM   4415  C  CA  . THR A 1 608 ? 148.233 194.257 107.171 1.00 118.01 ?  597 THR A CA  1 
ATOM   4416  C  C   . THR A 1 608 ? 149.438 194.807 107.904 1.00 118.01 ?  597 THR A C   1 
ATOM   4417  O  O   . THR A 1 608 ? 150.161 195.650 107.377 1.00 118.01 ?  597 THR A O   1 
ATOM   4418  C  CB  . THR A 1 608 ? 146.963 194.908 107.739 1.00 118.01 ?  597 THR A CB  1 
ATOM   4419  O  OG1 . THR A 1 608 ? 145.823 194.440 107.010 1.00 118.01 ?  597 THR A OG1 1 
ATOM   4420  C  CG2 . THR A 1 608 ? 147.044 196.421 107.628 1.00 118.01 ?  597 THR A CG2 1 
ATOM   4421  N  N   . VAL A 1 609 ? 149.667 194.321 109.116 1.00 119.32 ?  598 VAL A N   1 
ATOM   4422  C  CA  . VAL A 1 609 ? 150.805 194.781 109.895 1.00 119.32 ?  598 VAL A CA  1 
ATOM   4423  C  C   . VAL A 1 609 ? 151.829 193.675 110.050 1.00 119.32 ?  598 VAL A C   1 
ATOM   4424  O  O   . VAL A 1 609 ? 151.517 192.604 110.561 1.00 119.32 ?  598 VAL A O   1 
ATOM   4425  C  CB  . VAL A 1 609 ? 150.372 195.251 111.289 1.00 119.32 ?  598 VAL A CB  1 
ATOM   4426  C  CG1 . VAL A 1 609 ? 151.587 195.551 112.152 1.00 119.32 ?  598 VAL A CG1 1 
ATOM   4427  C  CG2 . VAL A 1 609 ? 149.471 196.471 111.175 1.00 119.32 ?  598 VAL A CG2 1 
ATOM   4428  N  N   . ASP A 1 610 ? 153.051 193.929 109.606 1.00 120.99 ?  599 ASP A N   1 
ATOM   4429  C  CA  . ASP A 1 610 ? 154.107 192.942 109.749 1.00 120.99 ?  599 ASP A CA  1 
ATOM   4430  C  C   . ASP A 1 610 ? 154.739 193.078 111.122 1.00 120.99 ?  599 ASP A C   1 
ATOM   4431  O  O   . ASP A 1 610 ? 154.421 194.011 111.858 1.00 120.99 ?  599 ASP A O   1 
ATOM   4432  C  CB  . ASP A 1 610 ? 155.150 193.126 108.653 1.00 120.99 ?  599 ASP A CB  1 
ATOM   4433  C  CG  . ASP A 1 610 ? 154.532 193.185 107.271 1.00 120.99 ?  599 ASP A CG  1 
ATOM   4434  O  OD1 . ASP A 1 610 ? 153.317 192.919 107.150 1.00 120.99 ?  599 ASP A OD1 1 
ATOM   4435  O  OD2 . ASP A 1 610 ? 155.260 193.497 106.306 1.00 120.99 -1 599 ASP A OD2 1 
ATOM   4436  N  N   . THR A 1 611 ? 155.619 192.148 111.478 1.00 119.04 ?  600 THR A N   1 
ATOM   4437  C  CA  . THR A 1 611 ? 156.286 192.194 112.782 1.00 119.04 ?  600 THR A CA  1 
ATOM   4438  C  C   . THR A 1 611 ? 155.349 192.757 113.846 1.00 119.04 ?  600 THR A C   1 
ATOM   4439  O  O   . THR A 1 611 ? 155.616 193.805 114.432 1.00 119.04 ?  600 THR A O   1 
ATOM   4440  C  CB  . THR A 1 611 ? 157.616 192.989 112.738 1.00 119.04 ?  600 THR A CB  1 
ATOM   4441  O  OG1 . THR A 1 611 ? 158.142 193.113 114.066 1.00 119.04 ?  600 THR A OG1 1 
ATOM   4442  C  CG2 . THR A 1 611 ? 157.419 194.380 112.142 1.00 119.04 ?  600 THR A CG2 1 
ATOM   4443  N  N   . ILE A 1 612 ? 154.233 192.081 114.075 1.00 116.32 ?  601 ILE A N   1 
ATOM   4444  C  CA  . ILE A 1 612 ? 153.250 192.577 115.032 1.00 116.32 ?  601 ILE A CA  1 
ATOM   4445  C  C   . ILE A 1 612 ? 153.676 192.385 116.472 1.00 116.32 ?  601 ILE A C   1 
ATOM   4446  O  O   . ILE A 1 612 ? 154.775 191.906 116.747 1.00 116.32 ?  601 ILE A O   1 
ATOM   4447  C  CB  . ILE A 1 612 ? 151.949 191.774 114.934 1.00 116.32 ?  601 ILE A CB  1 
ATOM   4448  N  N   . LYS A 1 613 ? 152.796 192.751 117.396 1.00 113.63 ?  602 LYS A N   1 
ATOM   4449  C  CA  . LYS A 1 613 ? 153.121 192.662 118.812 1.00 113.63 ?  602 LYS A CA  1 
ATOM   4450  C  C   . LYS A 1 613 ? 153.248 191.210 119.238 1.00 113.63 ?  602 LYS A C   1 
ATOM   4451  O  O   . LYS A 1 613 ? 152.809 190.309 118.525 1.00 113.63 ?  602 LYS A O   1 
ATOM   4452  C  CB  . LYS A 1 613 ? 152.039 193.353 119.633 1.00 113.63 ?  602 LYS A CB  1 
ATOM   4453  C  CG  . LYS A 1 613 ? 151.723 194.762 119.165 1.00 113.63 ?  602 LYS A CG  1 
ATOM   4454  C  CD  . LYS A 1 613 ? 150.395 195.236 119.727 1.00 113.63 ?  602 LYS A CD  1 
ATOM   4455  C  CE  . LYS A 1 613 ? 149.260 194.336 119.268 1.00 113.63 ?  602 LYS A CE  1 
ATOM   4456  N  NZ  . LYS A 1 613 ? 147.950 194.772 119.822 1.00 113.63 1  602 LYS A NZ  1 
ATOM   4457  N  N   . ASP A 1 614 ? 153.850 190.977 120.397 1.00 113.39 ?  603 ASP A N   1 
ATOM   4458  C  CA  . ASP A 1 614 ? 154.002 189.617 120.898 1.00 113.39 ?  603 ASP A CA  1 
ATOM   4459  C  C   . ASP A 1 614 ? 153.539 189.525 122.344 1.00 113.39 ?  603 ASP A C   1 
ATOM   4460  O  O   . ASP A 1 614 ? 154.358 189.425 123.258 1.00 113.39 ?  603 ASP A O   1 
ATOM   4461  C  CB  . ASP A 1 614 ? 155.458 189.163 120.777 1.00 113.39 ?  603 ASP A CB  1 
ATOM   4462  C  CG  . ASP A 1 614 ? 155.640 187.692 121.103 1.00 113.39 ?  603 ASP A CG  1 
ATOM   4463  O  OD1 . ASP A 1 614 ? 156.800 187.252 121.236 1.00 113.39 ?  603 ASP A OD1 1 
ATOM   4464  O  OD2 . ASP A 1 614 ? 154.624 186.975 121.228 1.00 113.39 -1 603 ASP A OD2 1 
ATOM   4465  N  N   . SER A 1 615 ? 152.229 189.559 122.557 1.00 108.90 ?  604 SER A N   1 
ATOM   4466  C  CA  . SER A 1 615 ? 151.694 189.508 123.913 1.00 108.90 ?  604 SER A CA  1 
ATOM   4467  C  C   . SER A 1 615 ? 150.705 188.361 124.090 1.00 108.90 ?  604 SER A C   1 
ATOM   4468  O  O   . SER A 1 615 ? 149.672 188.318 123.423 1.00 108.90 ?  604 SER A O   1 
ATOM   4469  C  CB  . SER A 1 615 ? 151.024 190.838 124.259 1.00 108.90 ?  604 SER A CB  1 
ATOM   4470  O  OG  . SER A 1 615 ? 149.975 191.130 123.352 1.00 108.90 ?  604 SER A OG  1 
ATOM   4471  N  N   . ASP A 1 616 ? 151.014 187.434 124.993 1.00 102.38 ?  605 ASP A N   1 
ATOM   4472  C  CA  . ASP A 1 616 ? 150.120 186.306 125.241 1.00 102.38 ?  605 ASP A CA  1 
ATOM   4473  C  C   . ASP A 1 616 ? 148.947 186.719 126.114 1.00 102.38 ?  605 ASP A C   1 
ATOM   4474  O  O   . ASP A 1 616 ? 149.071 187.622 126.939 1.00 102.38 ?  605 ASP A O   1 
ATOM   4475  C  CB  . ASP A 1 616 ? 150.879 185.152 125.895 1.00 102.38 ?  605 ASP A CB  1 
ATOM   4476  C  CG  . ASP A 1 616 ? 152.006 184.634 125.028 1.00 102.38 ?  605 ASP A CG  1 
ATOM   4477  O  OD1 . ASP A 1 616 ? 152.631 183.622 125.409 1.00 102.38 ?  605 ASP A OD1 1 
ATOM   4478  O  OD2 . ASP A 1 616 ? 152.267 185.236 123.965 1.00 102.38 -1 605 ASP A OD2 1 
ATOM   4479  N  N   . GLU A 1 617 ? 147.809 186.061 125.936 1.00 90.52  ?  606 GLU A N   1 
ATOM   4480  C  CA  . GLU A 1 617 ? 146.623 186.400 126.714 1.00 90.52  ?  606 GLU A CA  1 
ATOM   4481  C  C   . GLU A 1 617 ? 146.807 186.113 128.199 1.00 90.52  ?  606 GLU A C   1 
ATOM   4482  O  O   . GLU A 1 617 ? 146.280 186.843 129.038 1.00 90.52  ?  606 GLU A O   1 
ATOM   4483  C  CB  . GLU A 1 617 ? 145.397 185.650 126.188 1.00 90.52  ?  606 GLU A CB  1 
ATOM   4484  C  CG  . GLU A 1 617 ? 144.901 186.141 124.840 1.00 90.52  ?  606 GLU A CG  1 
ATOM   4485  C  CD  . GLU A 1 617 ? 143.572 185.525 124.453 1.00 90.52  ?  606 GLU A CD  1 
ATOM   4486  O  OE1 . GLU A 1 617 ? 143.133 184.580 125.141 1.00 90.52  ?  606 GLU A OE1 1 
ATOM   4487  O  OE2 . GLU A 1 617 ? 142.968 185.987 123.462 1.00 90.52  -1 606 GLU A OE2 1 
ATOM   4488  N  N   . GLU A 1 618 ? 147.542 185.055 128.530 1.00 85.66  ?  607 GLU A N   1 
ATOM   4489  C  CA  . GLU A 1 618 ? 147.719 184.683 129.931 1.00 85.66  ?  607 GLU A CA  1 
ATOM   4490  C  C   . GLU A 1 618 ? 146.369 184.497 130.600 1.00 85.66  ?  607 GLU A C   1 
ATOM   4491  O  O   . GLU A 1 618 ? 146.037 185.218 131.536 1.00 85.66  ?  607 GLU A O   1 
ATOM   4492  C  CB  . GLU A 1 618 ? 148.536 185.741 130.670 1.00 85.66  ?  607 GLU A CB  1 
ATOM   4493  C  CG  . GLU A 1 618 ? 149.983 185.848 130.216 1.00 85.66  ?  607 GLU A CG  1 
ATOM   4494  C  CD  . GLU A 1 618 ? 150.869 184.775 130.820 1.00 85.66  ?  607 GLU A CD  1 
ATOM   4495  O  OE1 . GLU A 1 618 ? 150.380 184.010 131.678 1.00 85.66  ?  607 GLU A OE1 1 
ATOM   4496  O  OE2 . GLU A 1 618 ? 152.057 184.700 130.443 1.00 85.66  -1 607 GLU A OE2 1 
ATOM   4497  N  N   . LEU A 1 619 ? 145.588 183.537 130.123 1.00 77.15  ?  608 LEU A N   1 
ATOM   4498  C  CA  . LEU A 1 619 ? 144.255 183.309 130.668 1.00 77.15  ?  608 LEU A CA  1 
ATOM   4499  C  C   . LEU A 1 619 ? 144.313 182.875 132.122 1.00 77.15  ?  608 LEU A C   1 
ATOM   4500  O  O   . LEU A 1 619 ? 145.265 182.221 132.538 1.00 77.15  ?  608 LEU A O   1 
ATOM   4501  C  CB  . LEU A 1 619 ? 143.511 182.259 129.838 1.00 77.15  ?  608 LEU A CB  1 
ATOM   4502  C  CG  . LEU A 1 619 ? 143.180 182.568 128.376 1.00 77.15  ?  608 LEU A CG  1 
ATOM   4503  C  CD1 . LEU A 1 619 ? 144.426 182.494 127.510 1.00 77.15  ?  608 LEU A CD1 1 
ATOM   4504  C  CD2 . LEU A 1 619 ? 142.139 181.583 127.872 1.00 77.15  ?  608 LEU A CD2 1 
ATOM   4505  N  N   . ASP A 1 620 ? 143.298 183.240 132.896 1.00 70.87  ?  609 ASP A N   1 
ATOM   4506  C  CA  . ASP A 1 620 ? 143.310 182.921 134.320 1.00 70.87  ?  609 ASP A CA  1 
ATOM   4507  C  C   . ASP A 1 620 ? 142.854 181.500 134.592 1.00 70.87  ?  609 ASP A C   1 
ATOM   4508  O  O   . ASP A 1 620 ? 142.483 180.777 133.673 1.00 70.87  ?  609 ASP A O   1 
ATOM   4509  C  CB  . ASP A 1 620 ? 142.462 183.927 135.114 1.00 70.87  ?  609 ASP A CB  1 
ATOM   4510  C  CG  . ASP A 1 620 ? 140.980 183.816 134.819 1.00 70.87  ?  609 ASP A CG  1 
ATOM   4511  O  OD1 . ASP A 1 620 ? 140.231 184.737 135.203 1.00 70.87  ?  609 ASP A OD1 1 
ATOM   4512  O  OD2 . ASP A 1 620 ? 140.557 182.819 134.209 1.00 70.87  -1 609 ASP A OD2 1 
ATOM   4513  N  N   . ASN A 1 621 ? 142.884 181.099 135.855 1.00 61.92  ?  610 ASN A N   1 
ATOM   4514  C  CA  . ASN A 1 621 ? 142.514 179.739 136.212 1.00 61.92  ?  610 ASN A CA  1 
ATOM   4515  C  C   . ASN A 1 621 ? 141.059 179.468 135.902 1.00 61.92  ?  610 ASN A C   1 
ATOM   4516  O  O   . ASN A 1 621 ? 140.669 178.323 135.707 1.00 61.92  ?  610 ASN A O   1 
ATOM   4517  C  CB  . ASN A 1 621 ? 142.787 179.487 137.695 1.00 61.92  ?  610 ASN A CB  1 
ATOM   4518  C  CG  . ASN A 1 621 ? 144.263 179.464 138.024 1.00 61.92  ?  610 ASN A CG  1 
ATOM   4519  O  OD1 . ASN A 1 621 ? 145.096 179.907 137.236 1.00 61.92  ?  610 ASN A OD1 1 
ATOM   4520  N  ND2 . ASN A 1 621 ? 144.595 178.947 139.200 1.00 61.92  ?  610 ASN A ND2 1 
ATOM   4521  N  N   . ASN A 1 622 ? 140.250 180.515 135.850 1.00 67.05  ?  611 ASN A N   1 
ATOM   4522  C  CA  . ASN A 1 622 ? 138.822 180.330 135.626 1.00 67.05  ?  611 ASN A CA  1 
ATOM   4523  C  C   . ASN A 1 622 ? 138.396 180.561 134.180 1.00 67.05  ?  611 ASN A C   1 
ATOM   4524  O  O   . ASN A 1 622 ? 137.206 180.594 133.888 1.00 67.05  ?  611 ASN A O   1 
ATOM   4525  C  CB  . ASN A 1 622 ? 138.034 181.248 136.559 1.00 67.05  ?  611 ASN A CB  1 
ATOM   4526  C  CG  . ASN A 1 622 ? 138.213 180.887 138.021 1.00 67.05  ?  611 ASN A CG  1 
ATOM   4527  O  OD1 . ASN A 1 622 ? 137.905 181.679 138.910 1.00 67.05  ?  611 ASN A OD1 1 
ATOM   4528  N  ND2 . ASN A 1 622 ? 138.718 179.686 138.278 1.00 67.05  ?  611 ASN A ND2 1 
ATOM   4529  N  N   . GLN A 1 623 ? 139.354 180.718 133.278 1.00 70.81  ?  612 GLN A N   1 
ATOM   4530  C  CA  . GLN A 1 623 ? 139.038 180.918 131.870 1.00 70.81  ?  612 GLN A CA  1 
ATOM   4531  C  C   . GLN A 1 623 ? 139.826 179.995 130.959 1.00 70.81  ?  612 GLN A C   1 
ATOM   4532  O  O   . GLN A 1 623 ? 139.520 179.890 129.777 1.00 70.81  ?  612 GLN A O   1 
ATOM   4533  C  CB  . GLN A 1 623 ? 139.331 182.360 131.470 1.00 70.81  ?  612 GLN A CB  1 
ATOM   4534  C  CG  . GLN A 1 623 ? 138.464 183.394 132.163 1.00 70.81  ?  612 GLN A CG  1 
ATOM   4535  C  CD  . GLN A 1 623 ? 139.095 184.770 132.152 1.00 70.81  ?  612 GLN A CD  1 
ATOM   4536  O  OE1 . GLN A 1 623 ? 138.469 185.756 132.540 1.00 70.81  ?  612 GLN A OE1 1 
ATOM   4537  N  NE2 . GLN A 1 623 ? 140.346 184.843 131.709 1.00 70.81  ?  612 GLN A NE2 1 
ATOM   4538  N  N   . ILE A 1 624 ? 140.831 179.317 131.491 1.00 66.53  ?  613 ILE A N   1 
ATOM   4539  C  CA  . ILE A 1 624 ? 141.691 178.480 130.660 1.00 66.53  ?  613 ILE A CA  1 
ATOM   4540  C  C   . ILE A 1 624 ? 140.943 177.320 130.006 1.00 66.53  ?  613 ILE A C   1 
ATOM   4541  O  O   . ILE A 1 624 ? 141.440 176.717 129.061 1.00 66.53  ?  613 ILE A O   1 
ATOM   4542  C  CB  . ILE A 1 624 ? 142.884 177.946 131.484 1.00 66.53  ?  613 ILE A CB  1 
ATOM   4543  C  CG1 . ILE A 1 624 ? 143.976 177.400 130.564 1.00 66.53  ?  613 ILE A CG1 1 
ATOM   4544  C  CG2 . ILE A 1 624 ? 142.416 176.893 132.479 1.00 66.53  ?  613 ILE A CG2 1 
ATOM   4545  C  CD1 . ILE A 1 624 ? 145.185 176.877 131.305 1.00 66.53  ?  613 ILE A CD1 1 
ATOM   4546  N  N   . GLU A 1 625 ? 139.748 177.016 130.490 1.00 68.36  ?  614 GLU A N   1 
ATOM   4547  C  CA  . GLU A 1 625 ? 138.983 175.893 129.954 1.00 68.36  ?  614 GLU A CA  1 
ATOM   4548  C  C   . GLU A 1 625 ? 138.437 176.163 128.562 1.00 68.36  ?  614 GLU A C   1 
ATOM   4549  O  O   . GLU A 1 625 ? 137.997 175.243 127.877 1.00 68.36  ?  614 GLU A O   1 
ATOM   4550  C  CB  . GLU A 1 625 ? 137.824 175.549 130.890 1.00 68.36  ?  614 GLU A CB  1 
ATOM   4551  C  CG  . GLU A 1 625 ? 138.204 175.463 132.361 1.00 68.36  ?  614 GLU A CG  1 
ATOM   4552  C  CD  . GLU A 1 625 ? 138.327 176.824 133.025 1.00 68.36  ?  614 GLU A CD  1 
ATOM   4553  O  OE1 . GLU A 1 625 ? 138.012 177.840 132.371 1.00 68.36  ?  614 GLU A OE1 1 
ATOM   4554  O  OE2 . GLU A 1 625 ? 138.734 176.878 134.203 1.00 68.36  -1 614 GLU A OE2 1 
ATOM   4555  N  N   . VAL A 1 626 ? 138.451 177.420 128.142 1.00 66.15  ?  615 VAL A N   1 
ATOM   4556  C  CA  . VAL A 1 626 ? 137.939 177.780 126.827 1.00 66.15  ?  615 VAL A CA  1 
ATOM   4557  C  C   . VAL A 1 626 ? 138.826 177.226 125.717 1.00 66.15  ?  615 VAL A C   1 
ATOM   4558  O  O   . VAL A 1 626 ? 138.370 177.044 124.590 1.00 66.15  ?  615 VAL A O   1 
ATOM   4559  C  CB  . VAL A 1 626 ? 137.823 179.307 126.688 1.00 66.15  ?  615 VAL A CB  1 
ATOM   4560  C  CG1 . VAL A 1 626 ? 139.202 179.943 126.631 1.00 66.15  ?  615 VAL A CG1 1 
ATOM   4561  C  CG2 . VAL A 1 626 ? 137.011 179.671 125.457 1.00 66.15  ?  615 VAL A CG2 1 
ATOM   4562  N  N   . LEU A 1 627 ? 140.083 176.943 126.030 1.00 61.93  ?  616 LEU A N   1 
ATOM   4563  C  CA  . LEU A 1 627 ? 141.018 176.451 125.028 1.00 61.93  ?  616 LEU A CA  1 
ATOM   4564  C  C   . LEU A 1 627 ? 140.802 174.980 124.726 1.00 61.93  ?  616 LEU A C   1 
ATOM   4565  O  O   . LEU A 1 627 ? 141.554 174.386 123.960 1.00 61.93  ?  616 LEU A O   1 
ATOM   4566  C  CB  . LEU A 1 627 ? 142.453 176.688 125.498 1.00 61.93  ?  616 LEU A CB  1 
ATOM   4567  C  CG  . LEU A 1 627 ? 142.833 178.134 125.796 1.00 61.93  ?  616 LEU A CG  1 
ATOM   4568  C  CD1 . LEU A 1 627 ? 144.257 178.198 126.319 1.00 61.93  ?  616 LEU A CD1 1 
ATOM   4569  C  CD2 . LEU A 1 627 ? 142.670 178.993 124.552 1.00 61.93  ?  616 LEU A CD2 1 
ATOM   4570  N  N   . ASP A 1 628 ? 139.776 174.391 125.321 1.00 65.84  ?  617 ASP A N   1 
ATOM   4571  C  CA  . ASP A 1 628 ? 139.499 172.980 125.110 1.00 65.84  ?  617 ASP A CA  1 
ATOM   4572  C  C   . ASP A 1 628 ? 138.220 172.785 124.333 1.00 65.84  ?  617 ASP A C   1 
ATOM   4573  O  O   . ASP A 1 628 ? 137.792 171.657 124.111 1.00 65.84  ?  617 ASP A O   1 
ATOM   4574  C  CB  . ASP A 1 628 ? 139.383 172.263 126.452 1.00 65.84  ?  617 ASP A CB  1 
ATOM   4575  C  CG  . ASP A 1 628 ? 140.656 172.338 127.269 1.00 65.84  ?  617 ASP A CG  1 
ATOM   4576  O  OD1 . ASP A 1 628 ? 141.510 173.200 126.980 1.00 65.84  ?  617 ASP A OD1 1 
ATOM   4577  O  OD2 . ASP A 1 628 ? 140.798 171.534 128.212 1.00 65.84  -1 617 ASP A OD2 1 
ATOM   4578  N  N   . GLN A 1 629 ? 137.606 173.879 123.911 1.00 67.59  ?  618 GLN A N   1 
ATOM   4579  C  CA  . GLN A 1 629 ? 136.340 173.794 123.203 1.00 67.59  ?  618 GLN A CA  1 
ATOM   4580  C  C   . GLN A 1 629 ? 136.535 173.583 121.708 1.00 67.59  ?  618 GLN A C   1 
ATOM   4581  O  O   . GLN A 1 629 ? 137.534 174.023 121.148 1.00 67.59  ?  618 GLN A O   1 
ATOM   4582  C  CB  . GLN A 1 629 ? 135.532 175.062 123.467 1.00 67.59  ?  618 GLN A CB  1 
ATOM   4583  C  CG  . GLN A 1 629 ? 135.264 175.317 124.939 1.00 67.59  ?  618 GLN A CG  1 
ATOM   4584  C  CD  . GLN A 1 629 ? 134.552 176.632 125.182 1.00 67.59  ?  618 GLN A CD  1 
ATOM   4585  O  OE1 . GLN A 1 629 ? 134.304 177.398 124.250 1.00 67.59  ?  618 GLN A OE1 1 
ATOM   4586  N  NE2 . GLN A 1 629 ? 134.221 176.903 126.439 1.00 67.59  ?  618 GLN A NE2 1 
ATOM   4587  N  N   . PRO A 1 630 ? 135.593 172.876 121.058 1.00 66.90  ?  619 PRO A N   1 
ATOM   4588  C  CA  . PRO A 1 630 ? 135.712 172.661 119.618 1.00 66.90  ?  619 PRO A CA  1 
ATOM   4589  C  C   . PRO A 1 630 ? 135.935 173.966 118.880 1.00 66.90  ?  619 PRO A C   1 
ATOM   4590  O  O   . PRO A 1 630 ? 135.241 174.940 119.151 1.00 66.90  ?  619 PRO A O   1 
ATOM   4591  C  CB  . PRO A 1 630 ? 134.356 172.077 119.246 1.00 66.90  ?  619 PRO A CB  1 
ATOM   4592  C  CG  . PRO A 1 630 ? 133.910 171.370 120.472 1.00 66.90  ?  619 PRO A CG  1 
ATOM   4593  C  CD  . PRO A 1 630 ? 134.380 172.231 121.602 1.00 66.90  ?  619 PRO A CD  1 
ATOM   4594  N  N   . ILE A 1 631 ? 136.890 173.989 117.962 1.00 70.53  ?  620 ILE A N   1 
ATOM   4595  C  CA  . ILE A 1 631 ? 137.173 175.194 117.202 1.00 70.53  ?  620 ILE A CA  1 
ATOM   4596  C  C   . ILE A 1 631 ? 136.116 175.429 116.146 1.00 70.53  ?  620 ILE A C   1 
ATOM   4597  O  O   . ILE A 1 631 ? 135.828 174.544 115.345 1.00 70.53  ?  620 ILE A O   1 
ATOM   4598  C  CB  . ILE A 1 631 ? 138.553 175.123 116.518 1.00 70.53  ?  620 ILE A CB  1 
ATOM   4599  C  CG1 . ILE A 1 631 ? 139.665 175.124 117.566 1.00 70.53  ?  620 ILE A CG1 1 
ATOM   4600  C  CG2 . ILE A 1 631 ? 138.732 176.278 115.548 1.00 70.53  ?  620 ILE A CG2 1 
ATOM   4601  C  CD1 . ILE A 1 631 ? 141.055 175.186 116.977 1.00 70.53  ?  620 ILE A CD1 1 
ATOM   4602  N  N   . ASN A 1 632 ? 135.521 176.612 116.142 1.00 86.69  ?  621 ASN A N   1 
ATOM   4603  C  CA  . ASN A 1 632 ? 134.553 176.950 115.110 1.00 86.69  ?  621 ASN A CA  1 
ATOM   4604  C  C   . ASN A 1 632 ? 135.025 178.212 114.424 1.00 86.69  ?  621 ASN A C   1 
ATOM   4605  O  O   . ASN A 1 632 ? 135.073 179.271 115.040 1.00 86.69  ?  621 ASN A O   1 
ATOM   4606  C  CB  . ASN A 1 632 ? 133.171 177.158 115.708 1.00 86.69  ?  621 ASN A CB  1 
ATOM   4607  C  CG  . ASN A 1 632 ? 132.150 177.592 114.677 1.00 86.69  ?  621 ASN A CG  1 
ATOM   4608  O  OD1 . ASN A 1 632 ? 132.418 177.578 113.477 1.00 86.69  ?  621 ASN A OD1 1 
ATOM   4609  N  ND2 . ASN A 1 632 ? 130.968 177.977 115.141 1.00 86.69  ?  621 ASN A ND2 1 
ATOM   4610  N  N   . THR A 1 633 ? 135.380 178.112 113.151 1.00 93.17  ?  622 THR A N   1 
ATOM   4611  C  CA  . THR A 1 633 ? 135.913 179.271 112.442 1.00 93.17  ?  622 THR A CA  1 
ATOM   4612  C  C   . THR A 1 633 ? 134.965 179.754 111.359 1.00 93.17  ?  622 THR A C   1 
ATOM   4613  O  O   . THR A 1 633 ? 135.383 180.435 110.427 1.00 93.17  ?  622 THR A O   1 
ATOM   4614  C  CB  . THR A 1 633 ? 137.288 178.967 111.814 1.00 93.17  ?  622 THR A CB  1 
ATOM   4615  O  OG1 . THR A 1 633 ? 137.192 177.797 110.992 1.00 93.17  ?  622 THR A OG1 1 
ATOM   4616  C  CG2 . THR A 1 633 ? 138.329 178.735 112.895 1.00 93.17  ?  622 THR A CG2 1 
ATOM   4617  N  N   . THR A 1 634 ? 133.689 179.414 111.484 1.00 98.78  ?  623 THR A N   1 
ATOM   4618  C  CA  . THR A 1 634 ? 132.700 179.852 110.507 1.00 98.78  ?  623 THR A CA  1 
ATOM   4619  C  C   . THR A 1 634 ? 132.753 181.355 110.351 1.00 98.78  ?  623 THR A C   1 
ATOM   4620  O  O   . THR A 1 634 ? 132.647 181.871 109.240 1.00 98.78  ?  623 THR A O   1 
ATOM   4621  C  CB  . THR A 1 634 ? 131.279 179.457 110.927 1.00 98.78  ?  623 THR A CB  1 
ATOM   4622  O  OG1 . THR A 1 634 ? 131.067 179.829 112.294 1.00 98.78  ?  623 THR A OG1 1 
ATOM   4623  C  CG2 . THR A 1 634 ? 131.078 177.958 110.780 1.00 98.78  ?  623 THR A CG2 1 
ATOM   4624  N  N   . ASP A 1 635 ? 132.924 182.065 111.459 1.00 104.51 ?  624 ASP A N   1 
ATOM   4625  C  CA  . ASP A 1 635 ? 133.030 183.511 111.399 1.00 104.51 ?  624 ASP A CA  1 
ATOM   4626  C  C   . ASP A 1 635 ? 133.899 183.885 110.228 1.00 104.51 ?  624 ASP A C   1 
ATOM   4627  O  O   . ASP A 1 635 ? 133.475 184.627 109.345 1.00 104.51 ?  624 ASP A O   1 
ATOM   4628  C  CB  . ASP A 1 635 ? 133.651 184.041 112.683 1.00 104.51 ?  624 ASP A CB  1 
ATOM   4629  C  CG  . ASP A 1 635 ? 134.112 185.476 112.554 1.00 104.51 ?  624 ASP A CG  1 
ATOM   4630  O  OD1 . ASP A 1 635 ? 133.250 186.376 112.474 1.00 104.51 ?  624 ASP A OD1 1 
ATOM   4631  O  OD2 . ASP A 1 635 ? 135.340 185.704 112.535 1.00 104.51 -1 624 ASP A OD2 1 
ATOM   4632  N  N   . LEU A 1 636 ? 135.120 183.369 110.210 1.00 105.49 ?  625 LEU A N   1 
ATOM   4633  C  CA  . LEU A 1 636 ? 136.008 183.623 109.091 1.00 105.49 ?  625 LEU A CA  1 
ATOM   4634  C  C   . LEU A 1 636 ? 135.489 182.854 107.891 1.00 105.49 ?  625 LEU A C   1 
ATOM   4635  O  O   . LEU A 1 636 ? 135.210 181.662 107.990 1.00 105.49 ?  625 LEU A O   1 
ATOM   4636  C  CB  . LEU A 1 636 ? 137.424 183.190 109.441 1.00 105.49 ?  625 LEU A CB  1 
ATOM   4637  C  CG  . LEU A 1 636 ? 137.959 183.760 110.753 1.00 105.49 ?  625 LEU A CG  1 
ATOM   4638  C  CD1 . LEU A 1 636 ? 139.264 183.088 111.147 1.00 105.49 ?  625 LEU A CD1 1 
ATOM   4639  C  CD2 . LEU A 1 636 ? 138.131 185.266 110.645 1.00 105.49 ?  625 LEU A CD2 1 
ATOM   4640  N  N   . PRO A 1 637 ? 135.355 183.530 106.745 1.00 110.51 ?  626 PRO A N   1 
ATOM   4641  C  CA  . PRO A 1 637 ? 134.773 182.860 105.569 1.00 110.51 ?  626 PRO A CA  1 
ATOM   4642  C  C   . PRO A 1 637 ? 135.517 181.611 105.122 1.00 110.51 ?  626 PRO A C   1 
ATOM   4643  O  O   . PRO A 1 637 ? 134.873 180.637 104.709 1.00 110.51 ?  626 PRO A O   1 
ATOM   4644  C  CB  . PRO A 1 637 ? 134.815 183.947 104.483 1.00 110.51 ?  626 PRO A CB  1 
ATOM   4645  C  CG  . PRO A 1 637 ? 135.045 185.234 105.220 1.00 110.51 ?  626 PRO A CG  1 
ATOM   4646  C  CD  . PRO A 1 637 ? 135.848 184.872 106.419 1.00 110.51 ?  626 PRO A CD  1 
ATOM   4647  N  N   . PHE A 1 638 ? 136.842 181.596 105.197 1.00 110.76 ?  627 PHE A N   1 
ATOM   4648  C  CA  . PHE A 1 638 ? 137.640 180.537 104.596 1.00 110.76 ?  627 PHE A CA  1 
ATOM   4649  C  C   . PHE A 1 638 ? 138.098 179.537 105.648 1.00 110.76 ?  627 PHE A C   1 
ATOM   4650  O  O   . PHE A 1 638 ? 138.041 179.811 106.851 1.00 110.76 ?  627 PHE A O   1 
ATOM   4651  C  CB  . PHE A 1 638 ? 138.859 181.116 103.880 1.00 110.76 ?  627 PHE A CB  1 
ATOM   4652  C  CG  . PHE A 1 638 ? 139.821 181.800 104.798 1.00 110.76 ?  627 PHE A CG  1 
ATOM   4653  C  CD1 . PHE A 1 638 ? 139.579 183.084 105.244 1.00 110.76 ?  627 PHE A CD1 1 
ATOM   4654  C  CD2 . PHE A 1 638 ? 140.964 181.151 105.223 1.00 110.76 ?  627 PHE A CD2 1 
ATOM   4655  C  CE1 . PHE A 1 638 ? 140.461 183.710 106.089 1.00 110.76 ?  627 PHE A CE1 1 
ATOM   4656  C  CE2 . PHE A 1 638 ? 141.848 181.770 106.067 1.00 110.76 ?  627 PHE A CE2 1 
ATOM   4657  C  CZ  . PHE A 1 638 ? 141.596 183.053 106.500 1.00 110.76 ?  627 PHE A CZ  1 
ATOM   4658  N  N   . HIS A 1 639 ? 138.550 178.376 105.183 1.00 105.22 ?  628 HIS A N   1 
ATOM   4659  C  CA  . HIS A 1 639 ? 139.076 177.359 106.081 1.00 105.22 ?  628 HIS A CA  1 
ATOM   4660  C  C   . HIS A 1 639 ? 140.531 177.646 106.431 1.00 105.22 ?  628 HIS A C   1 
ATOM   4661  O  O   . HIS A 1 639 ? 141.327 178.036 105.575 1.00 105.22 ?  628 HIS A O   1 
ATOM   4662  C  CB  . HIS A 1 639 ? 138.961 175.980 105.443 1.00 105.22 ?  628 HIS A CB  1 
ATOM   4663  C  CG  . HIS A 1 639 ? 137.599 175.379 105.562 1.00 105.22 ?  628 HIS A CG  1 
ATOM   4664  N  ND1 . HIS A 1 639 ? 137.165 174.742 106.703 1.00 105.22 ?  628 HIS A ND1 1 
ATOM   4665  C  CD2 . HIS A 1 639 ? 136.566 175.331 104.689 1.00 105.22 ?  628 HIS A CD2 1 
ATOM   4666  C  CE1 . HIS A 1 639 ? 135.927 174.319 106.525 1.00 105.22 ?  628 HIS A CE1 1 
ATOM   4667  N  NE2 . HIS A 1 639 ? 135.540 174.663 105.310 1.00 105.22 ?  628 HIS A NE2 1 
ATOM   4668  N  N   . ILE A 1 640 ? 140.873 177.448 107.699 1.00 90.22  ?  629 ILE A N   1 
ATOM   4669  C  CA  . ILE A 1 640 ? 142.246 177.599 108.165 1.00 90.22  ?  629 ILE A CA  1 
ATOM   4670  C  C   . ILE A 1 640 ? 142.908 176.230 108.122 1.00 90.22  ?  629 ILE A C   1 
ATOM   4671  O  O   . ILE A 1 640 ? 142.594 175.354 108.932 1.00 90.22  ?  629 ILE A O   1 
ATOM   4672  C  CB  . ILE A 1 640 ? 142.303 178.193 109.575 1.00 90.22  ?  629 ILE A CB  1 
ATOM   4673  C  CG1 . ILE A 1 640 ? 141.584 179.534 109.617 1.00 90.22  ?  629 ILE A CG1 1 
ATOM   4674  C  CG2 . ILE A 1 640 ? 143.735 178.360 110.019 1.00 90.22  ?  629 ILE A CG2 1 
ATOM   4675  C  CD1 . ILE A 1 640 ? 141.516 180.129 110.995 1.00 90.22  ?  629 ILE A CD1 1 
ATOM   4676  N  N   . ASP A 1 641 ? 143.825 176.041 107.182 1.00 83.70  ?  630 ASP A N   1 
ATOM   4677  C  CA  . ASP A 1 641 ? 144.636 174.831 107.165 1.00 83.70  ?  630 ASP A CA  1 
ATOM   4678  C  C   . ASP A 1 641 ? 145.604 174.943 108.333 1.00 83.70  ?  630 ASP A C   1 
ATOM   4679  O  O   . ASP A 1 641 ? 146.564 175.714 108.289 1.00 83.70  ?  630 ASP A O   1 
ATOM   4680  C  CB  . ASP A 1 641 ? 145.372 174.693 105.839 1.00 83.70  ?  630 ASP A CB  1 
ATOM   4681  C  CG  . ASP A 1 641 ? 145.973 173.306 105.635 1.00 83.70  ?  630 ASP A CG  1 
ATOM   4682  O  OD1 . ASP A 1 641 ? 146.038 172.862 104.476 1.00 83.70  ?  630 ASP A OD1 1 
ATOM   4683  O  OD2 . ASP A 1 641 ? 146.354 172.646 106.623 1.00 83.70  -1 630 ASP A OD2 1 
ATOM   4684  N  N   . TRP A 1 642 ? 145.336 174.201 109.404 1.00 72.29  ?  631 TRP A N   1 
ATOM   4685  C  CA  . TRP A 1 642 ? 146.144 174.321 110.606 1.00 72.29  ?  631 TRP A CA  1 
ATOM   4686  C  C   . TRP A 1 642 ? 147.544 173.770 110.425 1.00 72.29  ?  631 TRP A C   1 
ATOM   4687  O  O   . TRP A 1 642 ? 148.419 174.069 111.242 1.00 72.29  ?  631 TRP A O   1 
ATOM   4688  C  CB  . TRP A 1 642 ? 145.453 173.617 111.764 1.00 72.29  ?  631 TRP A CB  1 
ATOM   4689  C  CG  . TRP A 1 642 ? 144.344 174.404 112.332 1.00 72.29  ?  631 TRP A CG  1 
ATOM   4690  C  CD1 . TRP A 1 642 ? 143.026 174.108 112.279 1.00 72.29  ?  631 TRP A CD1 1 
ATOM   4691  C  CD2 . TRP A 1 642 ? 144.453 175.635 113.040 1.00 72.29  ?  631 TRP A CD2 1 
ATOM   4692  N  NE1 . TRP A 1 642 ? 142.298 175.075 112.913 1.00 72.29  ?  631 TRP A NE1 1 
ATOM   4693  C  CE2 . TRP A 1 642 ? 143.155 176.028 113.390 1.00 72.29  ?  631 TRP A CE2 1 
ATOM   4694  C  CE3 . TRP A 1 642 ? 145.524 176.446 113.413 1.00 72.29  ?  631 TRP A CE3 1 
ATOM   4695  C  CZ2 . TRP A 1 642 ? 142.897 177.191 114.094 1.00 72.29  ?  631 TRP A CZ2 1 
ATOM   4696  C  CZ3 . TRP A 1 642 ? 145.264 177.598 114.109 1.00 72.29  ?  631 TRP A CZ3 1 
ATOM   4697  C  CH2 . TRP A 1 642 ? 143.963 177.963 114.440 1.00 72.29  ?  631 TRP A CH2 1 
ATOM   4698  N  N   . ASN A 1 643 ? 147.778 172.990 109.379 1.00 75.78  ?  632 ASN A N   1 
ATOM   4699  C  CA  . ASN A 1 643 ? 149.084 172.406 109.130 1.00 75.78  ?  632 ASN A CA  1 
ATOM   4700  C  C   . ASN A 1 643 ? 149.900 173.195 108.121 1.00 75.78  ?  632 ASN A C   1 
ATOM   4701  O  O   . ASN A 1 643 ? 151.047 172.830 107.856 1.00 75.78  ?  632 ASN A O   1 
ATOM   4702  C  CB  . ASN A 1 643 ? 148.923 170.961 108.665 1.00 75.78  ?  632 ASN A CB  1 
ATOM   4703  C  CG  . ASN A 1 643 ? 148.140 170.124 109.652 1.00 75.78  ?  632 ASN A CG  1 
ATOM   4704  O  OD1 . ASN A 1 643 ? 148.357 170.202 110.856 1.00 75.78  ?  632 ASN A OD1 1 
ATOM   4705  N  ND2 . ASN A 1 643 ? 147.211 169.331 109.146 1.00 75.78  ?  632 ASN A ND2 1 
ATOM   4706  N  N   . ASP A 1 644 ? 149.353 174.311 107.659 1.00 83.56  ?  633 ASP A N   1 
ATOM   4707  C  CA  . ASP A 1 644 ? 150.101 175.192 106.787 1.00 83.56  ?  633 ASP A CA  1 
ATOM   4708  C  C   . ASP A 1 644 ? 150.485 176.391 107.645 1.00 83.56  ?  633 ASP A C   1 
ATOM   4709  O  O   . ASP A 1 644 ? 150.082 176.470 108.804 1.00 83.56  ?  633 ASP A O   1 
ATOM   4710  C  CB  . ASP A 1 644 ? 149.254 175.612 105.597 1.00 83.56  ?  633 ASP A CB  1 
ATOM   4711  C  CG  . ASP A 1 644 ? 150.065 176.303 104.519 1.00 83.56  ?  633 ASP A CG  1 
ATOM   4712  O  OD1 . ASP A 1 644 ? 149.461 176.778 103.535 1.00 83.56  ?  633 ASP A OD1 1 
ATOM   4713  O  OD2 . ASP A 1 644 ? 151.305 176.370 104.653 1.00 83.56  -1 633 ASP A OD2 1 
ATOM   4714  N  N   . ASP A 1 645 ? 151.255 177.326 107.102 1.00 88.77  ?  634 ASP A N   1 
ATOM   4715  C  CA  . ASP A 1 645 ? 151.726 178.465 107.897 1.00 88.77  ?  634 ASP A CA  1 
ATOM   4716  C  C   . ASP A 1 645 ? 150.604 179.394 108.341 1.00 88.77  ?  634 ASP A C   1 
ATOM   4717  O  O   . ASP A 1 645 ? 149.626 179.587 107.620 1.00 88.77  ?  634 ASP A O   1 
ATOM   4718  C  CB  . ASP A 1 645 ? 152.775 179.259 107.119 1.00 88.77  ?  634 ASP A CB  1 
ATOM   4719  C  CG  . ASP A 1 645 ? 154.016 178.441 106.822 1.00 88.77  ?  634 ASP A CG  1 
ATOM   4720  O  OD1 . ASP A 1 645 ? 154.878 178.920 106.056 1.00 88.77  ?  634 ASP A OD1 1 
ATOM   4721  O  OD2 . ASP A 1 645 ? 154.128 177.315 107.353 1.00 88.77  -1 634 ASP A OD2 1 
ATOM   4722  N  N   . LEU A 1 646 ? 150.747 179.971 109.529 1.00 92.17  ?  635 LEU A N   1 
ATOM   4723  C  CA  . LEU A 1 646 ? 149.721 180.864 110.052 1.00 92.17  ?  635 LEU A CA  1 
ATOM   4724  C  C   . LEU A 1 646 ? 150.143 182.317 109.913 1.00 92.17  ?  635 LEU A C   1 
ATOM   4725  O  O   . LEU A 1 646 ? 151.336 182.617 109.877 1.00 92.17  ?  635 LEU A O   1 
ATOM   4726  C  CB  . LEU A 1 646 ? 149.422 180.528 111.511 1.00 92.17  ?  635 LEU A CB  1 
ATOM   4727  C  CG  . LEU A 1 646 ? 148.935 179.108 111.795 1.00 92.17  ?  635 LEU A CG  1 
ATOM   4728  C  CD1 . LEU A 1 646 ? 148.863 178.861 113.294 1.00 92.17  ?  635 LEU A CD1 1 
ATOM   4729  C  CD2 . LEU A 1 646 ? 147.584 178.872 111.137 1.00 92.17  ?  635 LEU A CD2 1 
ATOM   4730  N  N   . PRO A 1 647 ? 149.167 183.233 109.843 1.00 98.63  ?  636 PRO A N   1 
ATOM   4731  C  CA  . PRO A 1 647 ? 149.493 184.648 109.625 1.00 98.63  ?  636 PRO A CA  1 
ATOM   4732  C  C   . PRO A 1 647 ? 150.231 185.319 110.769 1.00 98.63  ?  636 PRO A C   1 
ATOM   4733  O  O   . PRO A 1 647 ? 149.926 185.043 111.926 1.00 98.63  ?  636 PRO A O   1 
ATOM   4734  C  CB  . PRO A 1 647 ? 148.111 185.300 109.478 1.00 98.63  ?  636 PRO A CB  1 
ATOM   4735  C  CG  . PRO A 1 647 ? 147.178 184.387 110.197 1.00 98.63  ?  636 PRO A CG  1 
ATOM   4736  C  CD  . PRO A 1 647 ? 147.717 183.007 109.959 1.00 98.63  ?  636 PRO A CD  1 
ATOM   4737  N  N   . LEU A 1 648 ? 151.189 186.183 110.453 1.00 103.13 ?  637 LEU A N   1 
ATOM   4738  C  CA  . LEU A 1 648 ? 151.891 186.953 111.485 1.00 103.13 ?  637 LEU A CA  1 
ATOM   4739  C  C   . LEU A 1 648 ? 152.726 186.123 112.449 1.00 103.13 ?  637 LEU A C   1 
ATOM   4740  O  O   . LEU A 1 648 ? 152.814 186.460 113.629 1.00 103.13 ?  637 LEU A O   1 
ATOM   4741  C  CB  . LEU A 1 648 ? 150.882 187.819 112.253 1.00 103.13 ?  637 LEU A CB  1 
ATOM   4742  C  CG  . LEU A 1 648 ? 150.100 188.748 111.323 1.00 103.13 ?  637 LEU A CG  1 
ATOM   4743  C  CD1 . LEU A 1 648 ? 149.062 189.574 112.064 1.00 103.13 ?  637 LEU A CD1 1 
ATOM   4744  C  CD2 . LEU A 1 648 ? 151.061 189.643 110.560 1.00 103.13 ?  637 LEU A CD2 1 
ATOM   4745  N  N   . ASN A 1 649 ? 153.324 185.042 111.964 1.00 99.33  ?  638 ASN A N   1 
ATOM   4746  C  CA  . ASN A 1 649 ? 154.224 184.229 112.798 1.00 99.33  ?  638 ASN A CA  1 
ATOM   4747  C  C   . ASN A 1 649 ? 153.509 183.399 113.863 1.00 99.33  ?  638 ASN A C   1 
ATOM   4748  O  O   . ASN A 1 649 ? 154.154 182.667 114.612 1.00 99.33  ?  638 ASN A O   1 
ATOM   4749  C  CB  . ASN A 1 649 ? 155.296 185.114 113.452 1.00 99.33  ?  638 ASN A CB  1 
ATOM   4750  C  CG  . ASN A 1 649 ? 156.457 184.312 114.010 1.00 99.33  ?  638 ASN A CG  1 
ATOM   4751  O  OD1 . ASN A 1 649 ? 156.674 183.162 113.629 1.00 99.33  ?  638 ASN A OD1 1 
ATOM   4752  N  ND2 . ASN A 1 649 ? 157.216 184.923 114.911 1.00 99.33  ?  638 ASN A ND2 1 
ATOM   4753  N  N   . ILE A 1 650 ? 152.188 183.492 113.933 1.00 92.95  ?  639 ILE A N   1 
ATOM   4754  C  CA  . ILE A 1 650 ? 151.455 182.656 114.873 1.00 92.95  ?  639 ILE A CA  1 
ATOM   4755  C  C   . ILE A 1 650 ? 151.832 181.217 114.573 1.00 92.95  ?  639 ILE A C   1 
ATOM   4756  O  O   . ILE A 1 650 ? 151.799 180.801 113.418 1.00 92.95  ?  639 ILE A O   1 
ATOM   4757  C  CB  . ILE A 1 650 ? 149.944 182.879 114.748 1.00 92.95  ?  639 ILE A CB  1 
ATOM   4758  C  CG1 . ILE A 1 650 ? 149.626 184.364 114.929 1.00 92.95  ?  639 ILE A CG1 1 
ATOM   4759  C  CG2 . ILE A 1 650 ? 149.196 182.039 115.769 1.00 92.95  ?  639 ILE A CG2 1 
ATOM   4760  C  CD1 . ILE A 1 650 ? 148.169 184.710 114.737 1.00 92.95  ?  639 ILE A CD1 1 
ATOM   4761  N  N   . GLU A 1 651 ? 152.208 180.449 115.588 1.00 88.46  ?  640 GLU A N   1 
ATOM   4762  C  CA  . GLU A 1 651 ? 152.690 179.088 115.325 1.00 88.46  ?  640 GLU A CA  1 
ATOM   4763  C  C   . GLU A 1 651 ? 152.027 177.986 116.139 1.00 88.46  ?  640 GLU A C   1 
ATOM   4764  O  O   . GLU A 1 651 ? 151.825 178.135 117.341 1.00 88.46  ?  640 GLU A O   1 
ATOM   4765  C  CB  . GLU A 1 651 ? 154.205 179.034 115.537 1.00 88.46  ?  640 GLU A CB  1 
ATOM   4766  C  CG  . GLU A 1 651 ? 154.665 179.627 116.857 1.00 88.46  ?  640 GLU A CG  1 
ATOM   4767  C  CD  . GLU A 1 651 ? 156.172 179.765 116.937 1.00 88.46  ?  640 GLU A CD  1 
ATOM   4768  O  OE1 . GLU A 1 651 ? 156.672 180.290 117.954 1.00 88.46  ?  640 GLU A OE1 1 
ATOM   4769  O  OE2 . GLU A 1 651 ? 156.858 179.352 115.979 1.00 88.46  -1 640 GLU A OE2 1 
ATOM   4770  N  N   . VAL A 1 652 ? 151.700 176.875 115.485 1.00 77.47  ?  641 VAL A N   1 
ATOM   4771  C  CA  . VAL A 1 652 ? 151.076 175.747 116.164 1.00 77.47  ?  641 VAL A CA  1 
ATOM   4772  C  C   . VAL A 1 652 ? 151.699 174.463 115.645 1.00 77.47  ?  641 VAL A C   1 
ATOM   4773  O  O   . VAL A 1 652 ? 151.937 174.339 114.448 1.00 77.47  ?  641 VAL A O   1 
ATOM   4774  C  CB  . VAL A 1 652 ? 149.559 175.718 115.915 1.00 77.47  ?  641 VAL A CB  1 
ATOM   4775  C  CG1 . VAL A 1 652 ? 148.939 174.446 116.469 1.00 77.47  ?  641 VAL A CG1 1 
ATOM   4776  C  CG2 . VAL A 1 652 ? 148.890 176.945 116.512 1.00 77.47  ?  641 VAL A CG2 1 
ATOM   4777  N  N   . PRO A 1 653 ? 151.977 173.497 116.533 1.00 72.70  ?  642 PRO A N   1 
ATOM   4778  C  CA  . PRO A 1 653 ? 152.494 172.207 116.070 1.00 72.70  ?  642 PRO A CA  1 
ATOM   4779  C  C   . PRO A 1 653 ? 151.664 171.658 114.923 1.00 72.70  ?  642 PRO A C   1 
ATOM   4780  O  O   . PRO A 1 653 ? 150.435 171.703 114.944 1.00 72.70  ?  642 PRO A O   1 
ATOM   4781  C  CB  . PRO A 1 653 ? 152.383 171.320 117.310 1.00 72.70  ?  642 PRO A CB  1 
ATOM   4782  C  CG  . PRO A 1 653 ? 152.404 172.253 118.433 1.00 72.70  ?  642 PRO A CG  1 
ATOM   4783  C  CD  . PRO A 1 653 ? 151.704 173.483 117.975 1.00 72.70  ?  642 PRO A CD  1 
ATOM   4784  N  N   . LYS A 1 654 ? 152.350 171.143 113.914 1.00 72.39  ?  643 LYS A N   1 
ATOM   4785  C  CA  . LYS A 1 654 ? 151.691 170.513 112.785 1.00 72.39  ?  643 LYS A CA  1 
ATOM   4786  C  C   . LYS A 1 654 ? 151.698 169.003 112.951 1.00 72.39  ?  643 LYS A C   1 
ATOM   4787  O  O   . LYS A 1 654 ? 152.650 168.420 113.472 1.00 72.39  ?  643 LYS A O   1 
ATOM   4788  C  CB  . LYS A 1 654 ? 152.378 170.897 111.478 1.00 72.39  ?  643 LYS A CB  1 
ATOM   4789  C  CG  . LYS A 1 654 ? 152.261 172.361 111.141 1.00 72.39  ?  643 LYS A CG  1 
ATOM   4790  C  CD  . LYS A 1 654 ? 153.347 172.786 110.182 1.00 72.39  ?  643 LYS A CD  1 
ATOM   4791  C  CE  . LYS A 1 654 ? 153.326 174.286 109.971 1.00 72.39  ?  643 LYS A CE  1 
ATOM   4792  N  NZ  . LYS A 1 654 ? 154.601 174.782 109.392 1.00 72.39  1  643 LYS A NZ  1 
ATOM   4793  N  N   . ILE A 1 655 ? 150.622 168.370 112.504 1.00 61.91  ?  644 ILE A N   1 
ATOM   4794  C  CA  . ILE A 1 655 ? 150.491 166.924 112.572 1.00 61.91  ?  644 ILE A CA  1 
ATOM   4795  C  C   . ILE A 1 655 ? 150.180 166.401 111.181 1.00 61.91  ?  644 ILE A C   1 
ATOM   4796  O  O   . ILE A 1 655 ? 149.468 167.047 110.407 1.00 61.91  ?  644 ILE A O   1 
ATOM   4797  C  CB  . ILE A 1 655 ? 149.407 166.494 113.581 1.00 61.91  ?  644 ILE A CB  1 
ATOM   4798  C  CG1 . ILE A 1 655 ? 148.035 166.959 113.131 1.00 61.91  ?  644 ILE A CG1 1 
ATOM   4799  C  CG2 . ILE A 1 655 ? 149.698 167.062 114.950 1.00 61.91  ?  644 ILE A CG2 1 
ATOM   4800  C  CD1 . ILE A 1 655 ? 146.975 166.581 114.071 1.00 61.91  ?  644 ILE A CD1 1 
ATOM   4801  N  N   . SER A 1 656 ? 150.738 165.238 110.856 1.00 58.31  ?  645 SER A N   1 
ATOM   4802  C  CA  . SER A 1 656 ? 150.467 164.608 109.574 1.00 58.31  ?  645 SER A CA  1 
ATOM   4803  C  C   . SER A 1 656 ? 149.318 163.619 109.644 1.00 58.31  ?  645 SER A C   1 
ATOM   4804  O  O   . SER A 1 656 ? 148.834 163.177 108.600 1.00 58.31  ?  645 SER A O   1 
ATOM   4805  C  CB  . SER A 1 656 ? 151.717 163.902 109.065 1.00 58.31  ?  645 SER A CB  1 
ATOM   4806  O  OG  . SER A 1 656 ? 152.197 162.987 110.028 1.00 58.31  ?  645 SER A OG  1 
ATOM   4807  N  N   . LEU A 1 657 ? 148.868 163.276 110.842 1.00 50.89  ?  646 LEU A N   1 
ATOM   4808  C  CA  . LEU A 1 657 ? 147.798 162.309 111.004 1.00 50.89  ?  646 LEU A CA  1 
ATOM   4809  C  C   . LEU A 1 657 ? 146.471 162.898 110.562 1.00 50.89  ?  646 LEU A C   1 
ATOM   4810  O  O   . LEU A 1 657 ? 146.095 163.989 110.990 1.00 50.89  ?  646 LEU A O   1 
ATOM   4811  C  CB  . LEU A 1 657 ? 147.715 161.877 112.462 1.00 50.89  ?  646 LEU A CB  1 
ATOM   4812  C  CG  . LEU A 1 657 ? 146.764 160.738 112.784 1.00 50.89  ?  646 LEU A CG  1 
ATOM   4813  C  CD1 . LEU A 1 657 ? 147.331 159.478 112.232 1.00 50.89  ?  646 LEU A CD1 1 
ATOM   4814  C  CD2 . LEU A 1 657 ? 146.561 160.624 114.268 1.00 50.89  ?  646 LEU A CD2 1 
ATOM   4815  N  N   . HIS A 1 658 ? 145.750 162.173 109.715 1.00 50.12  ?  647 HIS A N   1 
ATOM   4816  C  CA  . HIS A 1 658 ? 144.381 162.538 109.408 1.00 50.12  ?  647 HIS A CA  1 
ATOM   4817  C  C   . HIS A 1 658 ? 143.392 161.424 109.693 1.00 50.12  ?  647 HIS A C   1 
ATOM   4818  O  O   . HIS A 1 658 ? 142.188 161.681 109.691 1.00 50.12  ?  647 HIS A O   1 
ATOM   4819  C  CB  . HIS A 1 658 ? 144.240 162.997 107.946 1.00 50.12  ?  647 HIS A CB  1 
ATOM   4820  C  CG  . HIS A 1 658 ? 144.662 161.982 106.931 1.00 50.12  ?  647 HIS A CG  1 
ATOM   4821  N  ND1 . HIS A 1 658 ? 143.928 160.850 106.658 1.00 50.12  ?  647 HIS A ND1 1 
ATOM   4822  C  CD2 . HIS A 1 658 ? 145.723 161.950 106.095 1.00 50.12  ?  647 HIS A CD2 1 
ATOM   4823  C  CE1 . HIS A 1 658 ? 144.530 160.154 105.715 1.00 50.12  ?  647 HIS A CE1 1 
ATOM   4824  N  NE2 . HIS A 1 658 ? 145.621 160.800 105.354 1.00 50.12  ?  647 HIS A NE2 1 
ATOM   4825  N  N   . SER A 1 659 ? 143.855 160.209 109.955 1.00 46.74  ?  648 SER A N   1 
ATOM   4826  C  CA  . SER A 1 659 ? 142.965 159.086 110.202 1.00 46.74  ?  648 SER A CA  1 
ATOM   4827  C  C   . SER A 1 659 ? 143.594 158.171 111.233 1.00 46.74  ?  648 SER A C   1 
ATOM   4828  O  O   . SER A 1 659 ? 144.773 157.837 111.129 1.00 46.74  ?  648 SER A O   1 
ATOM   4829  C  CB  . SER A 1 659 ? 142.683 158.308 108.921 1.00 46.74  ?  648 SER A CB  1 
ATOM   4830  O  OG  . SER A 1 659 ? 142.009 159.106 107.977 1.00 46.74  ?  648 SER A OG  1 
ATOM   4831  N  N   . LEU A 1 660 ? 142.808 157.771 112.220 1.00 42.19  ?  649 LEU A N   1 
ATOM   4832  C  CA  . LEU A 1 660 ? 143.251 156.850 113.253 1.00 42.19  ?  649 LEU A CA  1 
ATOM   4833  C  C   . LEU A 1 660 ? 142.314 155.656 113.261 1.00 42.19  ?  649 LEU A C   1 
ATOM   4834  O  O   . LEU A 1 660 ? 141.101 155.819 113.396 1.00 42.19  ?  649 LEU A O   1 
ATOM   4835  C  CB  . LEU A 1 660 ? 143.283 157.536 114.617 1.00 42.19  ?  649 LEU A CB  1 
ATOM   4836  C  CG  . LEU A 1 660 ? 143.503 156.664 115.845 1.00 42.19  ?  649 LEU A CG  1 
ATOM   4837  C  CD1 . LEU A 1 660 ? 144.904 156.116 115.876 1.00 42.19  ?  649 LEU A CD1 1 
ATOM   4838  C  CD2 . LEU A 1 660 ? 143.209 157.456 117.089 1.00 42.19  ?  649 LEU A CD2 1 
ATOM   4839  N  N   . ILE A 1 661 ? 142.872 154.466 113.098 1.00 39.18  ?  650 ILE A N   1 
ATOM   4840  C  CA  . ILE A 1 661 ? 142.112 153.227 113.138 1.00 39.18  ?  650 ILE A CA  1 
ATOM   4841  C  C   . ILE A 1 661 ? 142.436 152.521 114.440 1.00 39.18  ?  650 ILE A C   1 
ATOM   4842  O  O   . ILE A 1 661 ? 143.606 152.306 114.762 1.00 39.18  ?  650 ILE A O   1 
ATOM   4843  C  CB  . ILE A 1 661 ? 142.427 152.333 111.931 1.00 39.18  ?  650 ILE A CB  1 
ATOM   4844  C  CG1 . ILE A 1 661 ? 142.107 153.062 110.632 1.00 39.18  ?  650 ILE A CG1 1 
ATOM   4845  C  CG2 . ILE A 1 661 ? 141.659 151.041 112.017 1.00 39.18  ?  650 ILE A CG2 1 
ATOM   4846  C  CD1 . ILE A 1 661 ? 142.565 152.341 109.423 1.00 39.18  ?  650 ILE A CD1 1 
ATOM   4847  N  N   . LEU A 1 662 ? 141.407 152.176 115.196 1.00 38.91  ?  651 LEU A N   1 
ATOM   4848  C  CA  . LEU A 1 662 ? 141.556 151.430 116.436 1.00 38.91  ?  651 LEU A CA  1 
ATOM   4849  C  C   . LEU A 1 662 ? 141.108 150.000 116.187 1.00 38.91  ?  651 LEU A C   1 
ATOM   4850  O  O   . LEU A 1 662 ? 139.925 149.745 115.963 1.00 38.91  ?  651 LEU A O   1 
ATOM   4851  C  CB  . LEU A 1 662 ? 140.751 152.073 117.560 1.00 38.91  ?  651 LEU A CB  1 
ATOM   4852  C  CG  . LEU A 1 662 ? 141.182 153.475 117.979 1.00 38.91  ?  651 LEU A CG  1 
ATOM   4853  C  CD1 . LEU A 1 662 ? 140.298 153.981 119.084 1.00 38.91  ?  651 LEU A CD1 1 
ATOM   4854  C  CD2 . LEU A 1 662 ? 142.627 153.488 118.409 1.00 38.91  ?  651 LEU A CD2 1 
ATOM   4855  N  N   . ASP A 1 663 ? 142.055 149.073 116.220 1.00 42.19  ?  652 ASP A N   1 
ATOM   4856  C  CA  . ASP A 1 663 ? 141.767 147.655 116.040 1.00 42.19  ?  652 ASP A CA  1 
ATOM   4857  C  C   . ASP A 1 663 ? 141.265 147.096 117.362 1.00 42.19  ?  652 ASP A C   1 
ATOM   4858  O  O   . ASP A 1 663 ? 142.041 146.862 118.287 1.00 42.19  ?  652 ASP A O   1 
ATOM   4859  C  CB  . ASP A 1 663 ? 143.007 146.919 115.555 1.00 42.19  ?  652 ASP A CB  1 
ATOM   4860  C  CG  . ASP A 1 663 ? 142.803 145.431 115.479 1.00 42.19  ?  652 ASP A CG  1 
ATOM   4861  O  OD1 . ASP A 1 663 ? 141.709 144.999 115.074 1.00 42.19  ?  652 ASP A OD1 1 
ATOM   4862  O  OD2 . ASP A 1 663 ? 143.739 144.687 115.815 1.00 42.19  -1 652 ASP A OD2 1 
ATOM   4863  N  N   . PHE A 1 664 ? 139.956 146.877 117.453 1.00 41.56  ?  653 PHE A N   1 
ATOM   4864  C  CA  . PHE A 1 664 ? 139.309 146.474 118.693 1.00 41.56  ?  653 PHE A CA  1 
ATOM   4865  C  C   . PHE A 1 664 ? 138.869 145.018 118.675 1.00 41.56  ?  653 PHE A C   1 
ATOM   4866  O  O   . PHE A 1 664 ? 137.910 144.657 119.357 1.00 41.56  ?  653 PHE A O   1 
ATOM   4867  C  CB  . PHE A 1 664 ? 138.110 147.376 118.971 1.00 41.56  ?  653 PHE A CB  1 
ATOM   4868  C  CG  . PHE A 1 664 ? 138.407 148.532 119.867 1.00 41.56  ?  653 PHE A CG  1 
ATOM   4869  C  CD1 . PHE A 1 664 ? 139.661 149.095 119.903 1.00 41.56  ?  653 PHE A CD1 1 
ATOM   4870  C  CD2 . PHE A 1 664 ? 137.426 149.057 120.677 1.00 41.56  ?  653 PHE A CD2 1 
ATOM   4871  C  CE1 . PHE A 1 664 ? 139.927 150.153 120.723 1.00 41.56  ?  653 PHE A CE1 1 
ATOM   4872  C  CE2 . PHE A 1 664 ? 137.692 150.115 121.498 1.00 41.56  ?  653 PHE A CE2 1 
ATOM   4873  C  CZ  . PHE A 1 664 ? 138.942 150.663 121.520 1.00 41.56  ?  653 PHE A CZ  1 
ATOM   4874  N  N   . SER A 1 665 ? 139.552 144.169 117.911 1.00 44.18  ?  654 SER A N   1 
ATOM   4875  C  CA  . SER A 1 665 ? 139.119 142.782 117.797 1.00 44.18  ?  654 SER A CA  1 
ATOM   4876  C  C   . SER A 1 665 ? 139.334 142.018 119.094 1.00 44.18  ?  654 SER A C   1 
ATOM   4877  O  O   . SER A 1 665 ? 138.510 141.179 119.466 1.00 44.18  ?  654 SER A O   1 
ATOM   4878  C  CB  . SER A 1 665 ? 139.846 142.096 116.649 1.00 44.18  ?  654 SER A CB  1 
ATOM   4879  O  OG  . SER A 1 665 ? 141.173 142.552 116.555 1.00 44.18  ?  654 SER A OG  1 
ATOM   4880  N  N   . ALA A 1 666 ? 140.426 142.291 119.795 1.00 43.30  ?  655 ALA A N   1 
ATOM   4881  C  CA  . ALA A 1 666 ? 140.739 141.608 121.038 1.00 43.30  ?  655 ALA A CA  1 
ATOM   4882  C  C   . ALA A 1 666 ? 140.206 142.329 122.264 1.00 43.30  ?  655 ALA A C   1 
ATOM   4883  O  O   . ALA A 1 666 ? 140.420 141.854 123.379 1.00 43.30  ?  655 ALA A O   1 
ATOM   4884  C  CB  . ALA A 1 666 ? 142.248 141.420 121.170 1.00 43.30  ?  655 ALA A CB  1 
ATOM   4885  N  N   . VAL A 1 667 ? 139.521 143.455 122.091 1.00 44.46  ?  656 VAL A N   1 
ATOM   4886  C  CA  . VAL A 1 667 ? 138.907 144.177 123.201 1.00 44.46  ?  656 VAL A CA  1 
ATOM   4887  C  C   . VAL A 1 667 ? 137.596 143.469 123.520 1.00 44.46  ?  656 VAL A C   1 
ATOM   4888  O  O   . VAL A 1 667 ? 136.575 143.718 122.888 1.00 44.46  ?  656 VAL A O   1 
ATOM   4889  C  CB  . VAL A 1 667 ? 138.694 145.655 122.872 1.00 44.46  ?  656 VAL A CB  1 
ATOM   4890  C  CG1 . VAL A 1 667 ? 138.054 146.369 124.037 1.00 44.46  ?  656 VAL A CG1 1 
ATOM   4891  C  CG2 . VAL A 1 667 ? 140.011 146.301 122.515 1.00 44.46  ?  656 VAL A CG2 1 
ATOM   4892  N  N   . SER A 1 668 ? 137.629 142.579 124.508 1.00 46.58  ?  657 SER A N   1 
ATOM   4893  C  CA  . SER A 1 668 ? 136.493 141.713 124.800 1.00 46.58  ?  657 SER A CA  1 
ATOM   4894  C  C   . SER A 1 668 ? 135.313 142.501 125.354 1.00 46.58  ?  657 SER A C   1 
ATOM   4895  O  O   . SER A 1 668 ? 134.177 142.331 124.909 1.00 46.58  ?  657 SER A O   1 
ATOM   4896  C  CB  . SER A 1 668 ? 136.915 140.624 125.784 1.00 46.58  ?  657 SER A CB  1 
ATOM   4897  O  OG  . SER A 1 668 ? 137.965 139.847 125.250 1.00 46.58  ?  657 SER A OG  1 
ATOM   4898  N  N   . PHE A 1 669 ? 135.582 143.318 126.339 1.00 44.41  ?  658 PHE A N   1 
ATOM   4899  C  CA  . PHE A 1 669 ? 134.548 144.102 126.924 1.00 44.41  ?  658 PHE A CA  1 
ATOM   4900  C  C   . PHE A 1 669 ? 135.084 145.468 127.223 1.00 44.41  ?  658 PHE A C   1 
ATOM   4901  O  O   . PHE A 1 669 ? 136.256 145.745 127.097 1.00 44.41  ?  658 PHE A O   1 
ATOM   4902  C  CB  . PHE A 1 669 ? 134.017 143.437 128.209 1.00 44.41  ?  658 PHE A CB  1 
ATOM   4903  C  CG  . PHE A 1 669 ? 135.048 143.269 129.290 1.00 44.41  ?  658 PHE A CG  1 
ATOM   4904  C  CD1 . PHE A 1 669 ? 135.290 144.284 130.195 1.00 44.41  ?  658 PHE A CD1 1 
ATOM   4905  C  CD2 . PHE A 1 669 ? 135.763 142.095 129.406 1.00 44.41  ?  658 PHE A CD2 1 
ATOM   4906  C  CE1 . PHE A 1 669 ? 136.235 144.136 131.178 1.00 44.41  ?  658 PHE A CE1 1 
ATOM   4907  C  CE2 . PHE A 1 669 ? 136.707 141.938 130.395 1.00 44.41  ?  658 PHE A CE2 1 
ATOM   4908  C  CZ  . PHE A 1 669 ? 136.943 142.961 131.285 1.00 44.41  ?  658 PHE A CZ  1 
ATOM   4909  N  N   . LEU A 1 670 ? 134.164 146.320 127.606 1.00 46.60  ?  659 LEU A N   1 
ATOM   4910  C  CA  . LEU A 1 670 ? 134.429 147.667 128.030 1.00 46.60  ?  659 LEU A CA  1 
ATOM   4911  C  C   . LEU A 1 670 ? 133.626 147.871 129.311 1.00 46.60  ?  659 LEU A C   1 
ATOM   4912  O  O   . LEU A 1 670 ? 132.666 147.171 129.578 1.00 46.60  ?  659 LEU A O   1 
ATOM   4913  C  CB  . LEU A 1 670 ? 134.013 148.676 126.963 1.00 46.60  ?  659 LEU A CB  1 
ATOM   4914  C  CG  . LEU A 1 670 ? 134.789 148.800 125.654 1.00 46.60  ?  659 LEU A CG  1 
ATOM   4915  C  CD1 . LEU A 1 670 ? 134.130 149.802 124.734 1.00 46.60  ?  659 LEU A CD1 1 
ATOM   4916  C  CD2 . LEU A 1 670 ? 136.247 149.159 125.858 1.00 46.60  ?  659 LEU A CD2 1 
ATOM   4917  N  N   . ASP A 1 671 ? 134.037 148.810 130.132 1.00 45.81  ?  660 ASP A N   1 
ATOM   4918  C  CA  . ASP A 1 671 ? 133.303 149.119 131.356 1.00 45.81  ?  660 ASP A CA  1 
ATOM   4919  C  C   . ASP A 1 671 ? 133.020 150.619 131.406 1.00 45.81  ?  660 ASP A C   1 
ATOM   4920  O  O   . ASP A 1 671 ? 133.473 151.338 130.537 1.00 45.81  ?  660 ASP A O   1 
ATOM   4921  C  CB  . ASP A 1 671 ? 133.976 148.535 132.606 1.00 45.81  ?  660 ASP A CB  1 
ATOM   4922  C  CG  . ASP A 1 671 ? 135.146 149.350 133.108 1.00 45.81  ?  660 ASP A CG  1 
ATOM   4923  O  OD1 . ASP A 1 671 ? 135.854 149.991 132.320 1.00 45.81  ?  660 ASP A OD1 1 
ATOM   4924  O  OD2 . ASP A 1 671 ? 135.368 149.336 134.324 1.00 45.81  -1 660 ASP A OD2 1 
ATOM   4925  N  N   . VAL A 1 672 ? 132.285 151.135 132.381 1.00 45.61  ?  661 VAL A N   1 
ATOM   4926  C  CA  . VAL A 1 672 ? 132.019 152.581 132.369 1.00 45.61  ?  661 VAL A CA  1 
ATOM   4927  C  C   . VAL A 1 672 ? 133.258 153.482 132.355 1.00 45.61  ?  661 VAL A C   1 
ATOM   4928  O  O   . VAL A 1 672 ? 133.255 154.508 131.700 1.00 45.61  ?  661 VAL A O   1 
ATOM   4929  C  CB  . VAL A 1 672 ? 131.017 153.049 133.448 1.00 45.61  ?  661 VAL A CB  1 
ATOM   4930  C  CG1 . VAL A 1 672 ? 129.648 152.457 133.206 1.00 45.61  ?  661 VAL A CG1 1 
ATOM   4931  C  CG2 . VAL A 1 672 ? 131.521 152.733 134.836 1.00 45.61  ?  661 VAL A CG2 1 
ATOM   4932  N  N   . SER A 1 673 ? 134.304 153.100 133.073 1.00 46.19  ?  662 SER A N   1 
ATOM   4933  C  CA  . SER A 1 673 ? 135.526 153.880 133.068 1.00 46.19  ?  662 SER A CA  1 
ATOM   4934  C  C   . SER A 1 673 ? 136.176 153.900 131.697 1.00 46.19  ?  662 SER A C   1 
ATOM   4935  O  O   . SER A 1 673 ? 136.651 154.928 131.256 1.00 46.19  ?  662 SER A O   1 
ATOM   4936  C  CB  . SER A 1 673 ? 136.531 153.328 134.073 1.00 46.19  ?  662 SER A CB  1 
ATOM   4937  O  OG  . SER A 1 673 ? 135.925 153.060 135.313 1.00 46.19  ?  662 SER A OG  1 
ATOM   4938  N  N   . SER A 1 674 ? 136.238 152.748 131.046 1.00 45.21  ?  663 SER A N   1 
ATOM   4939  C  CA  . SER A 1 674 ? 136.837 152.662 129.724 1.00 45.21  ?  663 SER A CA  1 
ATOM   4940  C  C   . SER A 1 674 ? 136.050 153.420 128.664 1.00 45.21  ?  663 SER A C   1 
ATOM   4941  O  O   . SER A 1 674 ? 136.636 153.978 127.759 1.00 45.21  ?  663 SER A O   1 
ATOM   4942  C  CB  . SER A 1 674 ? 137.169 151.229 129.312 1.00 45.21  ?  663 SER A CB  1 
ATOM   4943  O  OG  . SER A 1 674 ? 136.058 150.376 129.391 1.00 45.21  ?  663 SER A OG  1 
ATOM   4944  N  N   . VAL A 1 675 ? 134.727 153.388 128.739 1.00 48.82  ?  664 VAL A N   1 
ATOM   4945  C  CA  . VAL A 1 675 ? 133.932 154.118 127.772 1.00 48.82  ?  664 VAL A CA  1 
ATOM   4946  C  C   . VAL A 1 675 ? 134.023 155.612 128.065 1.00 48.82  ?  664 VAL A C   1 
ATOM   4947  O  O   . VAL A 1 675 ? 134.034 156.400 127.140 1.00 48.82  ?  664 VAL A O   1 
ATOM   4948  C  CB  . VAL A 1 675 ? 132.475 153.602 127.616 1.00 48.82  ?  664 VAL A CB  1 
ATOM   4949  C  CG1 . VAL A 1 675 ? 132.435 152.090 127.576 1.00 48.82  ?  664 VAL A CG1 1 
ATOM   4950  C  CG2 . VAL A 1 675 ? 131.566 154.116 128.705 1.00 48.82  ?  664 VAL A CG2 1 
ATOM   4951  N  N   . ARG A 1 676 ? 134.121 156.012 129.335 1.00 49.14  ?  665 ARG A N   1 
ATOM   4952  C  CA  . ARG A 1 676 ? 134.255 157.424 129.614 1.00 49.14  ?  665 ARG A CA  1 
ATOM   4953  C  C   . ARG A 1 676 ? 135.588 157.895 129.098 1.00 49.14  ?  665 ARG A C   1 
ATOM   4954  O  O   . ARG A 1 676 ? 135.667 158.909 128.449 1.00 49.14  ?  665 ARG A O   1 
ATOM   4955  C  CB  . ARG A 1 676 ? 134.121 157.700 131.102 1.00 49.14  ?  665 ARG A CB  1 
ATOM   4956  C  CG  . ARG A 1 676 ? 132.687 157.757 131.561 1.00 49.14  ?  665 ARG A CG  1 
ATOM   4957  C  CD  . ARG A 1 676 ? 132.584 157.707 133.071 1.00 49.14  ?  665 ARG A CD  1 
ATOM   4958  N  NE  . ARG A 1 676 ? 131.201 157.598 133.512 1.00 49.14  ?  665 ARG A NE  1 
ATOM   4959  C  CZ  . ARG A 1 676 ? 130.839 157.187 134.723 1.00 49.14  ?  665 ARG A CZ  1 
ATOM   4960  N  NH1 . ARG A 1 676 ? 131.761 156.842 135.605 1.00 49.14  1  665 ARG A NH1 1 
ATOM   4961  N  NH2 . ARG A 1 676 ? 129.556 157.117 135.047 1.00 49.14  ?  665 ARG A NH2 1 
ATOM   4962  N  N   . GLY A 1 677 ? 136.634 157.142 129.393 1.00 48.18  ?  666 GLY A N   1 
ATOM   4963  C  CA  . GLY A 1 677 ? 137.963 157.453 128.924 1.00 48.18  ?  666 GLY A CA  1 
ATOM   4964  C  C   . GLY A 1 677 ? 138.031 157.389 127.416 1.00 48.18  ?  666 GLY A C   1 
ATOM   4965  O  O   . GLY A 1 677 ? 138.688 158.203 126.795 1.00 48.18  ?  666 GLY A O   1 
ATOM   4966  N  N   . LEU A 1 678 ? 137.363 156.403 126.834 1.00 50.28  ?  667 LEU A N   1 
ATOM   4967  C  CA  . LEU A 1 678 ? 137.327 156.218 125.396 1.00 50.28  ?  667 LEU A CA  1 
ATOM   4968  C  C   . LEU A 1 678 ? 136.618 157.370 124.700 1.00 50.28  ?  667 LEU A C   1 
ATOM   4969  O  O   . LEU A 1 678 ? 137.131 157.912 123.751 1.00 50.28  ?  667 LEU A O   1 
ATOM   4970  C  CB  . LEU A 1 678 ? 136.638 154.906 125.052 1.00 50.28  ?  667 LEU A CB  1 
ATOM   4971  C  CG  . LEU A 1 678 ? 136.412 154.510 123.597 1.00 50.28  ?  667 LEU A CG  1 
ATOM   4972  C  CD1 . LEU A 1 678 ? 137.747 154.341 122.906 1.00 50.28  ?  667 LEU A CD1 1 
ATOM   4973  C  CD2 . LEU A 1 678 ? 135.580 153.251 123.441 1.00 50.28  ?  667 LEU A CD2 1 
ATOM   4974  N  N   . LYS A 1 679 ? 135.428 157.715 125.168 1.00 50.49  ?  668 LYS A N   1 
ATOM   4975  C  CA  . LYS A 1 679 ? 134.637 158.804 124.624 1.00 50.49  ?  668 LYS A CA  1 
ATOM   4976  C  C   . LYS A 1 679 ? 135.426 160.093 124.662 1.00 50.49  ?  668 LYS A C   1 
ATOM   4977  O  O   . LYS A 1 679 ? 135.389 160.871 123.719 1.00 50.49  ?  668 LYS A O   1 
ATOM   4978  C  CB  . LYS A 1 679 ? 133.349 158.965 125.427 1.00 30.00  ?  668 LYS A CB  1 
ATOM   4979  C  CG  . LYS A 1 679 ? 132.454 160.102 124.975 1.00 30.00  ?  668 LYS A CG  1 
ATOM   4980  C  CD  . LYS A 1 679 ? 131.870 159.837 123.601 1.00 30.00  ?  668 LYS A CD  1 
ATOM   4981  C  CE  . LYS A 1 679 ? 130.784 160.845 123.271 1.00 30.00  ?  668 LYS A CE  1 
ATOM   4982  N  NZ  . LYS A 1 679 ? 129.637 160.747 124.213 1.00 30.00  1  668 LYS A NZ  1 
ATOM   4983  N  N   . SER A 1 680 ? 136.153 160.277 125.748 1.00 50.49  ?  669 SER A N   1 
ATOM   4984  C  CA  . SER A 1 680 ? 136.982 161.436 125.955 1.00 50.49  ?  669 SER A CA  1 
ATOM   4985  C  C   . SER A 1 680 ? 138.075 161.523 124.886 1.00 50.49  ?  669 SER A C   1 
ATOM   4986  O  O   . SER A 1 680 ? 138.190 162.526 124.215 1.00 50.49  ?  669 SER A O   1 
ATOM   4987  C  CB  . SER A 1 680 ? 137.564 161.355 127.355 1.00 50.49  ?  669 SER A CB  1 
ATOM   4988  O  OG  . SER A 1 680 ? 138.267 162.519 127.677 1.00 50.49  ?  669 SER A OG  1 
ATOM   4989  N  N   . ILE A 1 681 ? 138.862 160.465 124.723 1.00 50.84  ?  670 ILE A N   1 
ATOM   4990  C  CA  . ILE A 1 681 ? 139.921 160.397 123.722 1.00 50.84  ?  670 ILE A CA  1 
ATOM   4991  C  C   . ILE A 1 681 ? 139.398 160.654 122.319 1.00 50.84  ?  670 ILE A C   1 
ATOM   4992  O  O   . ILE A 1 681 ? 139.974 161.438 121.577 1.00 50.84  ?  670 ILE A O   1 
ATOM   4993  C  CB  . ILE A 1 681 ? 140.609 159.016 123.730 1.00 50.84  ?  670 ILE A CB  1 
ATOM   4994  C  CG1 . ILE A 1 681 ? 141.014 158.622 125.148 1.00 50.84  ?  670 ILE A CG1 1 
ATOM   4995  C  CG2 . ILE A 1 681 ? 141.820 159.018 122.812 1.00 50.84  ?  670 ILE A CG2 1 
ATOM   4996  C  CD1 . ILE A 1 681 ? 141.530 157.205 125.263 1.00 50.84  ?  670 ILE A CD1 1 
ATOM   4997  N  N   . LEU A 1 682 ? 138.309 159.994 121.950 1.00 52.77  ?  671 LEU A N   1 
ATOM   4998  C  CA  . LEU A 1 682 ? 137.756 160.139 120.608 1.00 52.77  ?  671 LEU A CA  1 
ATOM   4999  C  C   . LEU A 1 682 ? 137.255 161.544 120.317 1.00 52.77  ?  671 LEU A C   1 
ATOM   5000  O  O   . LEU A 1 682 ? 137.489 162.071 119.238 1.00 52.77  ?  671 LEU A O   1 
ATOM   5001  C  CB  . LEU A 1 682 ? 136.634 159.121 120.389 1.00 52.77  ?  671 LEU A CB  1 
ATOM   5002  C  CG  . LEU A 1 682 ? 137.021 157.735 119.873 1.00 52.77  ?  671 LEU A CG  1 
ATOM   5003  C  CD1 . LEU A 1 682 ? 138.278 157.221 120.552 1.00 52.77  ?  671 LEU A CD1 1 
ATOM   5004  C  CD2 . LEU A 1 682 ? 135.868 156.770 120.085 1.00 52.77  ?  671 LEU A CD2 1 
ATOM   5005  N  N   . GLN A 1 683 ? 136.569 162.156 121.272 1.00 54.22  ?  672 GLN A N   1 
ATOM   5006  C  CA  . GLN A 1 683 ? 136.110 163.526 121.094 1.00 54.22  ?  672 GLN A CA  1 
ATOM   5007  C  C   . GLN A 1 683 ? 137.266 164.470 120.819 1.00 54.22  ?  672 GLN A C   1 
ATOM   5008  O  O   . GLN A 1 683 ? 137.155 165.366 119.997 1.00 54.22  ?  672 GLN A O   1 
ATOM   5009  C  CB  . GLN A 1 683 ? 135.338 163.997 122.320 1.00 54.22  ?  672 GLN A CB  1 
ATOM   5010  C  CG  . GLN A 1 683 ? 133.949 163.405 122.442 1.00 54.22  ?  672 GLN A CG  1 
ATOM   5011  C  CD  . GLN A 1 683 ? 133.253 163.829 123.718 1.00 54.22  ?  672 GLN A CD  1 
ATOM   5012  O  OE1 . GLN A 1 683 ? 132.027 163.821 123.801 1.00 54.22  ?  672 GLN A OE1 1 
ATOM   5013  N  NE2 . GLN A 1 683 ? 134.036 164.210 124.718 1.00 54.22  ?  672 GLN A NE2 1 
ATOM   5014  N  N   . GLU A 1 684 ? 138.386 164.256 121.488 1.00 51.30  ?  673 GLU A N   1 
ATOM   5015  C  CA  . GLU A 1 684 ? 139.542 165.116 121.286 1.00 51.30  ?  673 GLU A CA  1 
ATOM   5016  C  C   . GLU A 1 684 ? 140.156 164.968 119.901 1.00 51.30  ?  673 GLU A C   1 
ATOM   5017  O  O   . GLU A 1 684 ? 140.551 165.955 119.296 1.00 51.30  ?  673 GLU A O   1 
ATOM   5018  C  CB  . GLU A 1 684 ? 140.587 164.843 122.360 1.00 51.30  ?  673 GLU A CB  1 
ATOM   5019  C  CG  . GLU A 1 684 ? 140.066 165.072 123.763 1.00 51.30  ?  673 GLU A CG  1 
ATOM   5020  C  CD  . GLU A 1 684 ? 140.906 164.386 124.815 1.00 51.30  ?  673 GLU A CD  1 
ATOM   5021  O  OE1 . GLU A 1 684 ? 142.016 163.924 124.482 1.00 51.30  ?  673 GLU A OE1 1 
ATOM   5022  O  OE2 . GLU A 1 684 ? 140.453 164.306 125.975 1.00 51.30  -1 673 GLU A OE2 1 
ATOM   5023  N  N   . PHE A 1 685 ? 140.246 163.745 119.400 1.00 56.25  ?  674 PHE A N   1 
ATOM   5024  C  CA  . PHE A 1 685 ? 140.779 163.529 118.066 1.00 56.25  ?  674 PHE A CA  1 
ATOM   5025  C  C   . PHE A 1 685 ? 139.847 164.130 117.037 1.00 56.25  ?  674 PHE A C   1 
ATOM   5026  O  O   . PHE A 1 685 ? 140.287 164.751 116.077 1.00 56.25  ?  674 PHE A O   1 
ATOM   5027  C  CB  . PHE A 1 685 ? 140.995 162.044 117.795 1.00 56.25  ?  674 PHE A CB  1 
ATOM   5028  C  CG  . PHE A 1 685 ? 142.282 161.505 118.342 1.00 56.25  ?  674 PHE A CG  1 
ATOM   5029  C  CD1 . PHE A 1 685 ? 143.490 161.840 117.757 1.00 56.25  ?  674 PHE A CD1 1 
ATOM   5030  C  CD2 . PHE A 1 685 ? 142.282 160.652 119.431 1.00 56.25  ?  674 PHE A CD2 1 
ATOM   5031  C  CE1 . PHE A 1 685 ? 144.678 161.341 118.256 1.00 56.25  ?  674 PHE A CE1 1 
ATOM   5032  C  CE2 . PHE A 1 685 ? 143.465 160.149 119.933 1.00 56.25  ?  674 PHE A CE2 1 
ATOM   5033  C  CZ  . PHE A 1 685 ? 144.666 160.494 119.344 1.00 56.25  ?  674 PHE A CZ  1 
ATOM   5034  N  N   . ILE A 1 686 ? 138.552 163.972 117.251 1.00 59.21  ?  675 ILE A N   1 
ATOM   5035  C  CA  . ILE A 1 686 ? 137.573 164.502 116.309 1.00 59.21  ?  675 ILE A CA  1 
ATOM   5036  C  C   . ILE A 1 686 ? 137.571 166.026 116.281 1.00 59.21  ?  675 ILE A C   1 
ATOM   5037  O  O   . ILE A 1 686 ? 137.419 166.623 115.220 1.00 59.21  ?  675 ILE A O   1 
ATOM   5038  C  CB  . ILE A 1 686 ? 136.163 163.957 116.600 1.00 59.21  ?  675 ILE A CB  1 
ATOM   5039  C  CG1 . ILE A 1 686 ? 136.156 162.439 116.423 1.00 59.21  ?  675 ILE A CG1 1 
ATOM   5040  C  CG2 . ILE A 1 686 ? 135.141 164.606 115.687 1.00 59.21  ?  675 ILE A CG2 1 
ATOM   5041  C  CD1 . ILE A 1 686 ? 134.955 161.748 117.020 1.00 59.21  ?  675 ILE A CD1 1 
ATOM   5042  N  N   . ARG A 1 687 ? 137.769 166.660 117.428 1.00 61.33  ?  676 ARG A N   1 
ATOM   5043  C  CA  . ARG A 1 687 ? 137.820 168.121 117.477 1.00 61.33  ?  676 ARG A CA  1 
ATOM   5044  C  C   . ARG A 1 687 ? 139.082 168.695 116.840 1.00 61.33  ?  676 ARG A C   1 
ATOM   5045  O  O   . ARG A 1 687 ? 139.141 169.886 116.565 1.00 61.33  ?  676 ARG A O   1 
ATOM   5046  C  CB  . ARG A 1 687 ? 137.666 168.610 118.915 1.00 61.33  ?  676 ARG A CB  1 
ATOM   5047  C  CG  . ARG A 1 687 ? 136.286 168.360 119.482 1.00 61.33  ?  676 ARG A CG  1 
ATOM   5048  C  CD  . ARG A 1 687 ? 136.228 168.660 120.965 1.00 61.33  ?  676 ARG A CD  1 
ATOM   5049  N  NE  . ARG A 1 687 ? 134.972 168.186 121.531 1.00 61.33  ?  676 ARG A NE  1 
ATOM   5050  C  CZ  . ARG A 1 687 ? 134.643 168.290 122.811 1.00 61.33  ?  676 ARG A CZ  1 
ATOM   5051  N  NH1 . ARG A 1 687 ? 133.476 167.825 123.231 1.00 61.33  1  676 ARG A NH1 1 
ATOM   5052  N  NH2 . ARG A 1 687 ? 135.479 168.856 123.670 1.00 61.33  ?  676 ARG A NH2 1 
ATOM   5053  N  N   . ILE A 1 688 ? 140.081 167.862 116.592 1.00 63.26  ?  677 ILE A N   1 
ATOM   5054  C  CA  . ILE A 1 688 ? 141.279 168.329 115.904 1.00 63.26  ?  677 ILE A CA  1 
ATOM   5055  C  C   . ILE A 1 688 ? 141.245 167.820 114.474 1.00 63.26  ?  677 ILE A C   1 
ATOM   5056  O  O   . ILE A 1 688 ? 142.282 167.719 113.828 1.00 63.26  ?  677 ILE A O   1 
ATOM   5057  C  CB  . ILE A 1 688 ? 142.573 167.908 116.628 1.00 63.26  ?  677 ILE A CB  1 
ATOM   5058  C  CG1 . ILE A 1 688 ? 142.724 166.387 116.633 1.00 63.26  ?  677 ILE A CG1 1 
ATOM   5059  C  CG2 . ILE A 1 688 ? 142.589 168.459 118.044 1.00 63.26  ?  677 ILE A CG2 1 
ATOM   5060  C  CD1 . ILE A 1 688 ? 144.061 165.907 117.149 1.00 63.26  ?  677 ILE A CD1 1 
ATOM   5061  N  N   . LYS A 1 689 ? 140.070 167.518 113.946 1.00 62.53  ?  678 LYS A N   1 
ATOM   5062  C  CA  . LYS A 1 689 ? 139.869 167.048 112.560 1.00 62.53  ?  678 LYS A CA  1 
ATOM   5063  C  C   . LYS A 1 689 ? 140.570 165.769 112.084 1.00 62.53  ?  678 LYS A C   1 
ATOM   5064  O  O   . LYS A 1 689 ? 140.947 165.672 110.930 1.00 62.53  ?  678 LYS A O   1 
ATOM   5065  C  CB  . LYS A 1 689 ? 140.082 168.179 111.534 1.00 30.00  ?  678 LYS A CB  1 
ATOM   5066  C  CG  . LYS A 1 689 ? 139.350 169.475 111.843 1.00 30.00  ?  678 LYS A CG  1 
ATOM   5067  C  CD  . LYS A 1 689 ? 137.926 169.221 112.293 1.00 30.00  ?  678 LYS A CD  1 
ATOM   5068  C  CE  . LYS A 1 689 ? 137.066 170.470 112.213 1.00 30.00  ?  678 LYS A CE  1 
ATOM   5069  N  NZ  . LYS A 1 689 ? 137.535 171.565 113.105 1.00 30.00  1  678 LYS A NZ  1 
ATOM   5070  N  N   . VAL A 1 690 ? 140.709 164.788 112.965 1.00 53.88  ?  679 VAL A N   1 
ATOM   5071  C  CA  . VAL A 1 690 ? 141.308 163.507 112.629 1.00 53.88  ?  679 VAL A CA  1 
ATOM   5072  C  C   . VAL A 1 690 ? 140.174 162.499 112.624 1.00 53.88  ?  679 VAL A C   1 
ATOM   5073  O  O   . VAL A 1 690 ? 139.422 162.406 113.580 1.00 53.88  ?  679 VAL A O   1 
ATOM   5074  C  CB  . VAL A 1 690 ? 142.360 163.074 113.667 1.00 53.88  ?  679 VAL A CB  1 
ATOM   5075  C  CG1 . VAL A 1 690 ? 142.639 161.584 113.595 1.00 53.88  ?  679 VAL A CG1 1 
ATOM   5076  C  CG2 . VAL A 1 690 ? 143.636 163.877 113.519 1.00 53.88  ?  679 VAL A CG2 1 
ATOM   5077  N  N   . ASP A 1 691 ? 140.011 161.775 111.528 1.00 51.06  ?  680 ASP A N   1 
ATOM   5078  C  CA  . ASP A 1 691 ? 138.957 160.775 111.450 1.00 51.06  ?  680 ASP A CA  1 
ATOM   5079  C  C   . ASP A 1 691 ? 139.356 159.546 112.228 1.00 51.06  ?  680 ASP A C   1 
ATOM   5080  O  O   . ASP A 1 691 ? 140.468 159.098 112.130 1.00 51.06  ?  680 ASP A O   1 
ATOM   5081  C  CB  . ASP A 1 691 ? 138.641 160.451 110.007 1.00 51.06  ?  680 ASP A CB  1 
ATOM   5082  C  CG  . ASP A 1 691 ? 137.903 161.568 109.321 1.00 51.06  ?  680 ASP A CG  1 
ATOM   5083  O  OD1 . ASP A 1 691 ? 138.192 161.854 108.150 1.00 51.06  ?  680 ASP A OD1 1 
ATOM   5084  O  OD2 . ASP A 1 691 ? 137.033 162.183 109.953 1.00 51.06  -1 680 ASP A OD2 1 
ATOM   5085  N  N   . VAL A 1 692 ? 138.429 159.014 113.000 1.00 47.73  ?  681 VAL A N   1 
ATOM   5086  C  CA  . VAL A 1 692 ? 138.664 157.861 113.851 1.00 47.73  ?  681 VAL A CA  1 
ATOM   5087  C  C   . VAL A 1 692 ? 137.795 156.685 113.427 1.00 47.73  ?  681 VAL A C   1 
ATOM   5088  O  O   . VAL A 1 692 ? 136.657 156.862 113.058 1.00 47.73  ?  681 VAL A O   1 
ATOM   5089  C  CB  . VAL A 1 692 ? 138.411 158.215 115.330 1.00 47.73  ?  681 VAL A CB  1 
ATOM   5090  C  CG1 . VAL A 1 692 ? 138.682 157.016 116.230 1.00 47.73  ?  681 VAL A CG1 1 
ATOM   5091  C  CG2 . VAL A 1 692 ? 139.284 159.385 115.743 1.00 47.73  ?  681 VAL A CG2 1 
ATOM   5092  N  N   . TYR A 1 693 ? 138.378 155.492 113.381 1.00 43.55  ?  682 TYR A N   1 
ATOM   5093  C  CA  . TYR A 1 693 ? 137.669 154.282 112.986 1.00 43.55  ?  682 TYR A CA  1 
ATOM   5094  C  C   . TYR A 1 693 ? 137.901 153.177 113.963 1.00 43.55  ?  682 TYR A C   1 
ATOM   5095  O  O   . TYR A 1 693 ? 139.010 152.943 114.382 1.00 43.55  ?  682 TYR A O   1 
ATOM   5096  C  CB  . TYR A 1 693 ? 138.121 153.801 111.606 1.00 43.55  ?  682 TYR A CB  1 
ATOM   5097  C  CG  . TYR A 1 693 ? 138.038 154.867 110.573 1.00 43.55  ?  682 TYR A CG  1 
ATOM   5098  C  CD1 . TYR A 1 693 ? 136.919 155.001 109.785 1.00 43.55  ?  682 TYR A CD1 1 
ATOM   5099  C  CD2 . TYR A 1 693 ? 139.064 155.777 110.417 1.00 43.55  ?  682 TYR A CD2 1 
ATOM   5100  C  CE1 . TYR A 1 693 ? 136.831 156.004 108.857 1.00 43.55  ?  682 TYR A CE1 1 
ATOM   5101  C  CE2 . TYR A 1 693 ? 138.979 156.792 109.516 1.00 43.55  ?  682 TYR A CE2 1 
ATOM   5102  C  CZ  . TYR A 1 693 ? 137.864 156.896 108.732 1.00 43.55  ?  682 TYR A CZ  1 
ATOM   5103  O  OH  . TYR A 1 693 ? 137.793 157.894 107.808 1.00 43.55  ?  682 TYR A OH  1 
ATOM   5104  N  N   . ILE A 1 694 ? 136.832 152.515 114.354 1.00 41.19  ?  683 ILE A N   1 
ATOM   5105  C  CA  . ILE A 1 694 ? 136.929 151.367 115.239 1.00 41.19  ?  683 ILE A CA  1 
ATOM   5106  C  C   . ILE A 1 694 ? 136.514 150.145 114.442 1.00 41.19  ?  683 ILE A C   1 
ATOM   5107  O  O   . ILE A 1 694 ? 135.392 150.082 113.935 1.00 41.19  ?  683 ILE A O   1 
ATOM   5108  C  CB  . ILE A 1 694 ? 136.070 151.544 116.497 1.00 41.19  ?  683 ILE A CB  1 
ATOM   5109  C  CG1 . ILE A 1 694 ? 136.471 152.830 117.214 1.00 41.19  ?  683 ILE A CG1 1 
ATOM   5110  C  CG2 . ILE A 1 694 ? 136.250 150.373 117.421 1.00 41.19  ?  683 ILE A CG2 1 
ATOM   5111  C  CD1 . ILE A 1 694 ? 135.755 153.063 118.499 1.00 41.19  ?  683 ILE A CD1 1 
ATOM   5112  N  N   . VAL A 1 695 ? 137.421 149.186 114.315 1.00 40.65  ?  684 VAL A N   1 
ATOM   5113  C  CA  . VAL A 1 695 ? 137.212 148.033 113.456 1.00 40.65  ?  684 VAL A CA  1 
ATOM   5114  C  C   . VAL A 1 695 ? 137.344 146.765 114.280 1.00 40.65  ?  684 VAL A C   1 
ATOM   5115  O  O   . VAL A 1 695 ? 137.903 146.759 115.375 1.00 40.65  ?  684 VAL A O   1 
ATOM   5116  C  CB  . VAL A 1 695 ? 138.195 148.010 112.274 1.00 40.65  ?  684 VAL A CB  1 
ATOM   5117  C  CG1 . VAL A 1 695 ? 138.090 149.286 111.481 1.00 40.65  ?  684 VAL A CG1 1 
ATOM   5118  C  CG2 . VAL A 1 695 ? 139.602 147.811 112.773 1.00 40.65  ?  684 VAL A CG2 1 
ATOM   5119  N  N   . GLY A 1 696 ? 136.799 145.683 113.741 1.00 46.79  ?  685 GLY A N   1 
ATOM   5120  C  CA  . GLY A 1 696 ? 137.028 144.364 114.283 1.00 46.79  ?  685 GLY A CA  1 
ATOM   5121  C  C   . GLY A 1 696 ? 136.153 143.955 115.441 1.00 46.79  ?  685 GLY A C   1 
ATOM   5122  O  O   . GLY A 1 696 ? 136.438 142.936 116.071 1.00 46.79  ?  685 GLY A O   1 
ATOM   5123  N  N   . THR A 1 697 ? 135.104 144.702 115.744 1.00 52.15  ?  686 THR A N   1 
ATOM   5124  C  CA  . THR A 1 697 ? 134.204 144.351 116.828 1.00 52.15  ?  686 THR A CA  1 
ATOM   5125  C  C   . THR A 1 697 ? 133.015 143.570 116.288 1.00 52.15  ?  686 THR A C   1 
ATOM   5126  O  O   . THR A 1 697 ? 132.728 143.591 115.090 1.00 52.15  ?  686 THR A O   1 
ATOM   5127  C  CB  . THR A 1 697 ? 133.721 145.604 117.554 1.00 52.15  ?  686 THR A CB  1 
ATOM   5128  O  OG1 . THR A 1 697 ? 132.873 146.359 116.689 1.00 52.15  ?  686 THR A OG1 1 
ATOM   5129  C  CG2 . THR A 1 697 ? 134.888 146.460 117.940 1.00 52.15  ?  686 THR A CG2 1 
ATOM   5130  N  N   . ASP A 1 698 ? 132.337 142.856 117.181 1.00 60.01  ?  687 ASP A N   1 
ATOM   5131  C  CA  . ASP A 1 698 ? 131.113 142.166 116.810 1.00 60.01  ?  687 ASP A CA  1 
ATOM   5132  C  C   . ASP A 1 698 ? 129.896 143.024 117.156 1.00 60.01  ?  687 ASP A C   1 
ATOM   5133  O  O   . ASP A 1 698 ? 130.010 144.143 117.657 1.00 60.01  ?  687 ASP A O   1 
ATOM   5134  C  CB  . ASP A 1 698 ? 131.045 140.796 117.478 1.00 60.01  ?  687 ASP A CB  1 
ATOM   5135  C  CG  . ASP A 1 698 ? 131.183 140.871 118.976 1.00 60.01  ?  687 ASP A CG  1 
ATOM   5136  O  OD1 . ASP A 1 698 ? 130.472 140.126 119.681 1.00 60.01  ?  687 ASP A OD1 1 
ATOM   5137  O  OD2 . ASP A 1 698 ? 132.006 141.677 119.453 1.00 60.01  -1 687 ASP A OD2 1 
ATOM   5138  N  N   . ASP A 1 699 ? 128.709 142.487 116.884 1.00 62.25  ?  688 ASP A N   1 
ATOM   5139  C  CA  . ASP A 1 699 ? 127.474 143.253 116.997 1.00 62.25  ?  688 ASP A CA  1 
ATOM   5140  C  C   . ASP A 1 699 ? 127.045 143.455 118.443 1.00 62.25  ?  688 ASP A C   1 
ATOM   5141  O  O   . ASP A 1 699 ? 126.518 144.522 118.791 1.00 62.25  ?  688 ASP A O   1 
ATOM   5142  C  CB  . ASP A 1 699 ? 126.378 142.544 116.211 1.00 62.25  ?  688 ASP A CB  1 
ATOM   5143  C  CG  . ASP A 1 699 ? 126.695 142.456 114.732 1.00 62.25  ?  688 ASP A CG  1 
ATOM   5144  O  OD1 . ASP A 1 699 ? 127.883 142.608 114.373 1.00 62.25  ?  688 ASP A OD1 1 
ATOM   5145  O  OD2 . ASP A 1 699 ? 125.779 142.194 113.930 1.00 62.25  -1 688 ASP A OD2 1 
ATOM   5146  N  N   . ASP A 1 700 ? 127.252 142.443 119.287 1.00 64.01  ?  689 ASP A N   1 
ATOM   5147  C  CA  . ASP A 1 700 ? 127.014 142.592 120.715 1.00 64.01  ?  689 ASP A CA  1 
ATOM   5148  C  C   . ASP A 1 700 ? 127.791 143.764 121.284 1.00 64.01  ?  689 ASP A C   1 
ATOM   5149  O  O   . ASP A 1 700 ? 127.298 144.464 122.172 1.00 64.01  ?  689 ASP A O   1 
ATOM   5150  C  CB  . ASP A 1 700 ? 127.415 141.314 121.438 1.00 64.01  ?  689 ASP A CB  1 
ATOM   5151  C  CG  . ASP A 1 700 ? 126.660 140.108 120.948 1.00 64.01  ?  689 ASP A CG  1 
ATOM   5152  O  OD1 . ASP A 1 700 ? 125.474 139.952 121.297 1.00 64.01  ?  689 ASP A OD1 1 
ATOM   5153  O  OD2 . ASP A 1 700 ? 127.255 139.308 120.200 1.00 64.01  -1 689 ASP A OD2 1 
ATOM   5154  N  N   . PHE A 1 701 ? 129.001 143.992 120.775 1.00 57.29  ?  690 PHE A N   1 
ATOM   5155  C  CA  . PHE A 1 701 ? 129.833 145.087 121.251 1.00 57.29  ?  690 PHE A CA  1 
ATOM   5156  C  C   . PHE A 1 701 ? 129.165 146.433 121.008 1.00 57.29  ?  690 PHE A C   1 
ATOM   5157  O  O   . PHE A 1 701 ? 129.129 147.291 121.896 1.00 57.29  ?  690 PHE A O   1 
ATOM   5158  C  CB  . PHE A 1 701 ? 131.193 145.015 120.559 1.00 57.29  ?  690 PHE A CB  1 
ATOM   5159  C  CG  . PHE A 1 701 ? 132.243 145.886 121.173 1.00 57.29  ?  690 PHE A CG  1 
ATOM   5160  C  CD1 . PHE A 1 701 ? 132.411 147.188 120.754 1.00 57.29  ?  690 PHE A CD1 1 
ATOM   5161  C  CD2 . PHE A 1 701 ? 133.077 145.393 122.156 1.00 57.29  ?  690 PHE A CD2 1 
ATOM   5162  C  CE1 . PHE A 1 701 ? 133.372 147.981 121.311 1.00 57.29  ?  690 PHE A CE1 1 
ATOM   5163  C  CE2 . PHE A 1 701 ? 134.044 146.186 122.715 1.00 57.29  ?  690 PHE A CE2 1 
ATOM   5164  C  CZ  . PHE A 1 701 ? 134.192 147.478 122.288 1.00 57.29  ?  690 PHE A CZ  1 
ATOM   5165  N  N   . ILE A 1 702 ? 128.630 146.642 119.806 1.00 58.97  ?  691 ILE A N   1 
ATOM   5166  C  CA  . ILE A 1 702 ? 128.042 147.937 119.489 1.00 58.97  ?  691 ILE A CA  1 
ATOM   5167  C  C   . ILE A 1 702 ? 126.693 148.116 120.172 1.00 58.97  ?  691 ILE A C   1 
ATOM   5168  O  O   . ILE A 1 702 ? 126.351 149.229 120.587 1.00 58.97  ?  691 ILE A O   1 
ATOM   5169  C  CB  . ILE A 1 702 ? 127.948 148.110 117.967 1.00 58.97  ?  691 ILE A CB  1 
ATOM   5170  C  CG1 . ILE A 1 702 ? 129.298 147.774 117.341 1.00 58.97  ?  691 ILE A CG1 1 
ATOM   5171  C  CG2 . ILE A 1 702 ? 127.547 149.524 117.614 1.00 58.97  ?  691 ILE A CG2 1 
ATOM   5172  C  CD1 . ILE A 1 702 ? 129.262 147.574 115.856 1.00 58.97  ?  691 ILE A CD1 1 
ATOM   5173  N  N   . GLU A 1 703 ? 126.030 146.996 120.399 1.00 62.56  ?  692 GLU A N   1 
ATOM   5174  C  CA  . GLU A 1 703 ? 124.784 146.974 121.110 1.00 62.56  ?  692 GLU A CA  1 
ATOM   5175  C  C   . GLU A 1 703 ? 125.081 147.468 122.524 1.00 62.56  ?  692 GLU A C   1 
ATOM   5176  O  O   . GLU A 1 703 ? 124.389 148.330 123.028 1.00 62.56  ?  692 GLU A O   1 
ATOM   5177  C  CB  . GLU A 1 703 ? 124.250 145.547 121.126 1.00 62.56  ?  692 GLU A CB  1 
ATOM   5178  C  CG  . GLU A 1 703 ? 122.898 145.372 121.772 1.00 62.56  ?  692 GLU A CG  1 
ATOM   5179  C  CD  . GLU A 1 703 ? 122.778 144.036 122.470 1.00 62.56  ?  692 GLU A CD  1 
ATOM   5180  O  OE1 . GLU A 1 703 ? 123.832 143.429 122.767 1.00 62.56  ?  692 GLU A OE1 1 
ATOM   5181  O  OE2 . GLU A 1 703 ? 121.636 143.591 122.728 1.00 62.56  -1 692 GLU A OE2 1 
ATOM   5182  N  N   . LYS A 1 704 ? 126.129 146.936 123.147 1.00 59.89  ?  693 LYS A N   1 
ATOM   5183  C  CA  . LYS A 1 704 ? 126.529 147.327 124.492 1.00 59.89  ?  693 LYS A CA  1 
ATOM   5184  C  C   . LYS A 1 704 ? 126.945 148.788 124.534 1.00 59.89  ?  693 LYS A C   1 
ATOM   5185  O  O   . LYS A 1 704 ? 126.576 149.514 125.458 1.00 59.89  ?  693 LYS A O   1 
ATOM   5186  C  CB  . LYS A 1 704 ? 127.655 146.434 124.992 1.00 59.89  ?  693 LYS A CB  1 
ATOM   5187  C  CG  . LYS A 1 704 ? 127.206 145.058 125.396 1.00 59.89  ?  693 LYS A CG  1 
ATOM   5188  C  CD  . LYS A 1 704 ? 128.293 144.341 126.157 1.00 59.89  ?  693 LYS A CD  1 
ATOM   5189  C  CE  . LYS A 1 704 ? 127.811 143.013 126.702 1.00 59.89  ?  693 LYS A CE  1 
ATOM   5190  N  NZ  . LYS A 1 704 ? 127.555 142.034 125.619 1.00 59.89  1  693 LYS A NZ  1 
ATOM   5191  N  N   . LEU A 1 705 ? 127.704 149.236 123.538 1.00 57.27  ?  694 LEU A N   1 
ATOM   5192  C  CA  . LEU A 1 705 ? 128.149 150.622 123.484 1.00 57.27  ?  694 LEU A CA  1 
ATOM   5193  C  C   . LEU A 1 705 ? 126.998 151.601 123.302 1.00 57.27  ?  694 LEU A C   1 
ATOM   5194  O  O   . LEU A 1 705 ? 127.146 152.779 123.630 1.00 57.27  ?  694 LEU A O   1 
ATOM   5195  C  CB  . LEU A 1 705 ? 129.162 150.783 122.355 1.00 57.27  ?  694 LEU A CB  1 
ATOM   5196  C  CG  . LEU A 1 705 ? 130.275 151.811 122.504 1.00 57.27  ?  694 LEU A CG  1 
ATOM   5197  C  CD1 . LEU A 1 705 ? 130.921 151.730 123.862 1.00 57.27  ?  694 LEU A CD1 1 
ATOM   5198  C  CD2 . LEU A 1 705 ? 131.297 151.574 121.436 1.00 57.27  ?  694 LEU A CD2 1 
ATOM   5199  N  N   . ASN A 1 706 ? 125.867 151.149 122.765 1.00 60.66  ?  695 ASN A N   1 
ATOM   5200  C  CA  . ASN A 1 706 ? 124.717 152.037 122.627 1.00 60.66  ?  695 ASN A CA  1 
ATOM   5201  C  C   . ASN A 1 706 ? 124.063 152.341 123.968 1.00 60.66  ?  695 ASN A C   1 
ATOM   5202  O  O   . ASN A 1 706 ? 123.423 153.386 124.116 1.00 60.66  ?  695 ASN A O   1 
ATOM   5203  C  CB  . ASN A 1 706 ? 123.691 151.426 121.683 1.00 60.66  ?  695 ASN A CB  1 
ATOM   5204  C  CG  . ASN A 1 706 ? 124.035 151.647 120.242 1.00 60.66  ?  695 ASN A CG  1 
ATOM   5205  O  OD1 . ASN A 1 706 ? 123.995 152.771 119.750 1.00 60.66  ?  695 ASN A OD1 1 
ATOM   5206  N  ND2 . ASN A 1 706 ? 124.387 150.576 119.549 1.00 60.66  ?  695 ASN A ND2 1 
ATOM   5207  N  N   . ARG A 1 707 ? 124.192 151.443 124.945 1.00 59.87  ?  696 ARG A N   1 
ATOM   5208  C  CA  . ARG A 1 707 ? 123.586 151.681 126.248 1.00 59.87  ?  696 ARG A CA  1 
ATOM   5209  C  C   . ARG A 1 707 ? 124.362 152.705 127.056 1.00 59.87  ?  696 ARG A C   1 
ATOM   5210  O  O   . ARG A 1 707 ? 123.791 153.360 127.931 1.00 59.87  ?  696 ARG A O   1 
ATOM   5211  C  CB  . ARG A 1 707 ? 123.492 150.382 127.035 1.00 59.87  ?  696 ARG A CB  1 
ATOM   5212  C  CG  . ARG A 1 707 ? 122.713 149.299 126.354 1.00 59.87  ?  696 ARG A CG  1 
ATOM   5213  C  CD  . ARG A 1 707 ? 122.870 148.004 127.105 1.00 59.87  ?  696 ARG A CD  1 
ATOM   5214  N  NE  . ARG A 1 707 ? 122.757 146.848 126.226 1.00 59.87  ?  696 ARG A NE  1 
ATOM   5215  C  CZ  . ARG A 1 707 ? 123.315 145.670 126.475 1.00 59.87  ?  696 ARG A CZ  1 
ATOM   5216  N  NH1 . ARG A 1 707 ? 123.165 144.669 125.620 1.00 59.87  1  696 ARG A NH1 1 
ATOM   5217  N  NH2 . ARG A 1 707 ? 124.027 145.494 127.579 1.00 59.87  ?  696 ARG A NH2 1 
ATOM   5218  N  N   . TYR A 1 708 ? 125.654 152.854 126.789 1.00 55.82  ?  697 TYR A N   1 
ATOM   5219  C  CA  . TYR A 1 708 ? 126.489 153.758 127.560 1.00 55.82  ?  697 TYR A CA  1 
ATOM   5220  C  C   . TYR A 1 708 ? 126.291 155.214 127.202 1.00 55.82  ?  697 TYR A C   1 
ATOM   5221  O  O   . TYR A 1 708 ? 127.021 156.048 127.740 1.00 55.82  ?  697 TYR A O   1 
ATOM   5222  C  CB  . TYR A 1 708 ? 127.957 153.408 127.365 1.00 55.82  ?  697 TYR A CB  1 
ATOM   5223  C  CG  . TYR A 1 708 ? 128.409 152.171 128.078 1.00 55.82  ?  697 TYR A CG  1 
ATOM   5224  C  CD1 . TYR A 1 708 ? 128.399 150.950 127.444 1.00 55.82  ?  697 TYR A CD1 1 
ATOM   5225  C  CD2 . TYR A 1 708 ? 128.876 152.228 129.378 1.00 55.82  ?  697 TYR A CD2 1 
ATOM   5226  C  CE1 . TYR A 1 708 ? 128.825 149.817 128.084 1.00 55.82  ?  697 TYR A CE1 1 
ATOM   5227  C  CE2 . TYR A 1 708 ? 129.302 151.100 130.024 1.00 55.82  ?  697 TYR A CE2 1 
ATOM   5228  C  CZ  . TYR A 1 708 ? 129.276 149.897 129.372 1.00 55.82  ?  697 TYR A CZ  1 
ATOM   5229  O  OH  . TYR A 1 708 ? 129.700 148.763 130.010 1.00 55.82  ?  697 TYR A OH  1 
ATOM   5230  N  N   . GLU A 1 709 ? 125.343 155.543 126.332 1.00 59.69  ?  698 GLU A N   1 
ATOM   5231  C  CA  . GLU A 1 709 ? 125.217 156.884 125.768 1.00 59.69  ?  698 GLU A CA  1 
ATOM   5232  C  C   . GLU A 1 709 ? 126.568 157.363 125.238 1.00 59.69  ?  698 GLU A C   1 
ATOM   5233  O  O   . GLU A 1 709 ? 127.051 158.449 125.555 1.00 59.69  ?  698 GLU A O   1 
ATOM   5234  C  CB  . GLU A 1 709 ? 124.651 157.875 126.786 1.00 59.69  ?  698 GLU A CB  1 
ATOM   5235  C  CG  . GLU A 1 709 ? 123.198 157.660 127.169 1.00 59.69  ?  698 GLU A CG  1 
ATOM   5236  C  CD  . GLU A 1 709 ? 123.008 157.457 128.659 1.00 59.69  ?  698 GLU A CD  1 
ATOM   5237  O  OE1 . GLU A 1 709 ? 123.901 156.851 129.289 1.00 59.69  ?  698 GLU A OE1 1 
ATOM   5238  O  OE2 . GLU A 1 709 ? 121.984 157.924 129.202 1.00 59.69  -1 698 GLU A OE2 1 
ATOM   5239  N  N   . PHE A 1 710 ? 127.184 156.502 124.435 1.00 55.73  ?  699 PHE A N   1 
ATOM   5240  C  CA  . PHE A 1 710 ? 128.475 156.767 123.822 1.00 55.73  ?  699 PHE A CA  1 
ATOM   5241  C  C   . PHE A 1 710 ? 128.333 157.594 122.556 1.00 55.73  ?  699 PHE A C   1 
ATOM   5242  O  O   . PHE A 1 710 ? 129.084 158.549 122.350 1.00 55.73  ?  699 PHE A O   1 
ATOM   5243  C  CB  . PHE A 1 710 ? 129.168 155.439 123.523 1.00 55.73  ?  699 PHE A CB  1 
ATOM   5244  C  CG  . PHE A 1 710 ? 130.533 155.569 122.926 1.00 55.73  ?  699 PHE A CG  1 
ATOM   5245  C  CD1 . PHE A 1 710 ? 130.729 155.366 121.582 1.00 55.73  ?  699 PHE A CD1 1 
ATOM   5246  C  CD2 . PHE A 1 710 ? 131.625 155.844 123.718 1.00 55.73  ?  699 PHE A CD2 1 
ATOM   5247  C  CE1 . PHE A 1 710 ? 131.978 155.460 121.038 1.00 55.73  ?  699 PHE A CE1 1 
ATOM   5248  C  CE2 . PHE A 1 710 ? 132.873 155.938 123.174 1.00 55.73  ?  699 PHE A CE2 1 
ATOM   5249  C  CZ  . PHE A 1 710 ? 133.050 155.748 121.834 1.00 55.73  ?  699 PHE A CZ  1 
ATOM   5250  N  N   . PHE A 1 711 ? 127.366 157.257 121.718 1.00 56.12  ?  700 PHE A N   1 
ATOM   5251  C  CA  . PHE A 1 711 ? 127.165 157.952 120.463 1.00 56.12  ?  700 PHE A CA  1 
ATOM   5252  C  C   . PHE A 1 711 ? 126.314 159.190 120.668 1.00 56.12  ?  700 PHE A C   1 
ATOM   5253  O  O   . PHE A 1 711 ? 125.387 159.210 121.478 1.00 56.12  ?  700 PHE A O   1 
ATOM   5254  C  CB  . PHE A 1 711 ? 126.509 157.034 119.439 1.00 56.12  ?  700 PHE A CB  1 
ATOM   5255  C  CG  . PHE A 1 711 ? 127.282 155.798 119.180 1.00 56.12  ?  700 PHE A CG  1 
ATOM   5256  C  CD1 . PHE A 1 711 ? 128.528 155.864 118.598 1.00 56.12  ?  700 PHE A CD1 1 
ATOM   5257  C  CD2 . PHE A 1 711 ? 126.781 154.569 119.537 1.00 56.12  ?  700 PHE A CD2 1 
ATOM   5258  C  CE1 . PHE A 1 711 ? 129.245 154.731 118.368 1.00 56.12  ?  700 PHE A CE1 1 
ATOM   5259  C  CE2 . PHE A 1 711 ? 127.496 153.434 119.305 1.00 56.12  ?  700 PHE A CE2 1 
ATOM   5260  C  CZ  . PHE A 1 711 ? 128.729 153.514 118.722 1.00 56.12  ?  700 PHE A CZ  1 
ATOM   5261  N  N   . ASP A 1 712 ? 126.640 160.221 119.917 1.00 60.67  ?  701 ASP A N   1 
ATOM   5262  C  CA  . ASP A 1 712 ? 125.950 161.502 119.944 1.00 60.67  ?  701 ASP A CA  1 
ATOM   5263  C  C   . ASP A 1 712 ? 126.318 162.208 118.650 1.00 60.67  ?  701 ASP A C   1 
ATOM   5264  O  O   . ASP A 1 712 ? 126.822 161.583 117.711 1.00 60.67  ?  701 ASP A O   1 
ATOM   5265  C  CB  . ASP A 1 712 ? 126.332 162.314 121.182 1.00 60.67  ?  701 ASP A CB  1 
ATOM   5266  C  CG  . ASP A 1 712 ? 127.812 162.614 121.246 1.00 60.67  ?  701 ASP A CG  1 
ATOM   5267  O  OD1 . ASP A 1 712 ? 128.606 161.789 120.768 1.00 60.67  ?  701 ASP A OD1 1 
ATOM   5268  O  OD2 . ASP A 1 712 ? 128.186 163.678 121.772 1.00 60.67  -1 701 ASP A OD2 1 
ATOM   5269  N  N   . GLY A 1 713 ? 126.040 163.504 118.577 1.00 61.86  ?  702 GLY A N   1 
ATOM   5270  C  CA  . GLY A 1 713 ? 126.719 164.316 117.589 1.00 61.86  ?  702 GLY A CA  1 
ATOM   5271  C  C   . GLY A 1 713 ? 128.202 164.366 117.900 1.00 61.86  ?  702 GLY A C   1 
ATOM   5272  O  O   . GLY A 1 713 ? 128.610 164.384 119.062 1.00 61.86  ?  702 GLY A O   1 
ATOM   5273  N  N   . GLU A 1 714 ? 129.012 164.363 116.850 1.00 61.41  ?  703 GLU A N   1 
ATOM   5274  C  CA  . GLU A 1 714 ? 130.469 164.382 116.854 1.00 61.41  ?  703 GLU A CA  1 
ATOM   5275  C  C   . GLU A 1 714 ? 131.096 163.095 117.397 1.00 61.41  ?  703 GLU A C   1 
ATOM   5276  O  O   . GLU A 1 714 ? 132.314 163.031 117.499 1.00 61.41  ?  703 GLU A O   1 
ATOM   5277  C  CB  . GLU A 1 714 ? 131.041 165.428 117.833 1.00 61.41  ?  703 GLU A CB  1 
ATOM   5278  C  CG  . GLU A 1 714 ? 132.517 165.686 117.734 1.00 61.41  ?  703 GLU A CG  1 
ATOM   5279  C  CD  . GLU A 1 714 ? 133.128 165.981 119.077 1.00 61.41  ?  703 GLU A CD  1 
ATOM   5280  O  OE1 . GLU A 1 714 ? 132.798 167.025 119.670 1.00 61.41  ?  703 GLU A OE1 1 
ATOM   5281  O  OE2 . GLU A 1 714 ? 133.935 165.159 119.544 1.00 61.41  -1 703 GLU A OE2 1 
ATOM   5282  N  N   . VAL A 1 715 ? 130.331 162.042 117.658 1.00 57.52  ?  704 VAL A N   1 
ATOM   5283  C  CA  . VAL A 1 715 ? 130.827 160.673 117.754 1.00 57.52  ?  704 VAL A CA  1 
ATOM   5284  C  C   . VAL A 1 715 ? 129.696 159.770 117.305 1.00 57.52  ?  704 VAL A C   1 
ATOM   5285  O  O   . VAL A 1 715 ? 128.757 159.511 118.061 1.00 57.52  ?  704 VAL A O   1 
ATOM   5286  C  CB  . VAL A 1 715 ? 131.307 160.308 119.170 1.00 57.52  ?  704 VAL A CB  1 
ATOM   5287  C  CG1 . VAL A 1 715 ? 131.541 158.819 119.284 1.00 57.52  ?  704 VAL A CG1 1 
ATOM   5288  C  CG2 . VAL A 1 715 ? 132.581 161.026 119.494 1.00 57.52  ?  704 VAL A CG2 1 
ATOM   5289  N  N   . LYS A 1 716 ? 129.767 159.301 116.072 1.00 54.53  ?  705 LYS A N   1 
ATOM   5290  C  CA  . LYS A 1 716 ? 128.665 158.608 115.435 1.00 54.53  ?  705 LYS A CA  1 
ATOM   5291  C  C   . LYS A 1 716 ? 129.012 157.144 115.230 1.00 54.53  ?  705 LYS A C   1 
ATOM   5292  O  O   . LYS A 1 716 ? 130.176 156.753 115.234 1.00 54.53  ?  705 LYS A O   1 
ATOM   5293  C  CB  . LYS A 1 716 ? 128.329 159.277 114.104 1.00 54.53  ?  705 LYS A CB  1 
ATOM   5294  C  CG  . LYS A 1 716 ? 128.205 160.781 114.196 1.00 54.53  ?  705 LYS A CG  1 
ATOM   5295  C  CD  . LYS A 1 716 ? 128.412 161.416 112.848 1.00 54.53  ?  705 LYS A CD  1 
ATOM   5296  C  CE  . LYS A 1 716 ? 127.363 162.468 112.572 1.00 54.53  ?  705 LYS A CE  1 
ATOM   5297  N  NZ  . LYS A 1 716 ? 127.140 162.644 111.110 1.00 54.53  1  705 LYS A NZ  1 
ATOM   5298  N  N   . SER A 1 717 ? 127.979 156.329 115.046 1.00 51.91  ?  706 SER A N   1 
ATOM   5299  C  CA  . SER A 1 717 ? 128.187 154.920 114.752 1.00 51.91  ?  706 SER A CA  1 
ATOM   5300  C  C   . SER A 1 717 ? 128.784 154.692 113.371 1.00 51.91  ?  706 SER A C   1 
ATOM   5301  O  O   . SER A 1 717 ? 129.047 153.543 113.008 1.00 51.91  ?  706 SER A O   1 
ATOM   5302  C  CB  . SER A 1 717 ? 126.876 154.152 114.857 1.00 51.91  ?  706 SER A CB  1 
ATOM   5303  O  OG  . SER A 1 717 ? 125.942 154.583 113.892 1.00 51.91  ?  706 SER A OG  1 
ATOM   5304  N  N   . SER A 1 718 ? 128.977 155.747 112.586 1.00 48.08  ?  707 SER A N   1 
ATOM   5305  C  CA  . SER A 1 718 ? 129.673 155.647 111.319 1.00 48.08  ?  707 SER A CA  1 
ATOM   5306  C  C   . SER A 1 718 ? 131.150 155.331 111.481 1.00 48.08  ?  707 SER A C   1 
ATOM   5307  O  O   . SER A 1 718 ? 131.803 155.007 110.489 1.00 48.08  ?  707 SER A O   1 
ATOM   5308  C  CB  . SER A 1 718 ? 129.515 156.948 110.552 1.00 48.08  ?  707 SER A CB  1 
ATOM   5309  O  OG  . SER A 1 718 ? 128.249 157.514 110.795 1.00 48.08  ?  707 SER A OG  1 
ATOM   5310  N  N   . ILE A 1 719 ? 131.692 155.427 112.695 1.00 44.56  ?  708 ILE A N   1 
ATOM   5311  C  CA  . ILE A 1 719 ? 133.113 155.172 112.906 1.00 44.56  ?  708 ILE A CA  1 
ATOM   5312  C  C   . ILE A 1 719 ? 133.439 153.695 112.980 1.00 44.56  ?  708 ILE A C   1 
ATOM   5313  O  O   . ILE A 1 719 ? 134.615 153.336 113.020 1.00 44.56  ?  708 ILE A O   1 
ATOM   5314  C  CB  . ILE A 1 719 ? 133.622 155.856 114.186 1.00 44.56  ?  708 ILE A CB  1 
ATOM   5315  C  CG1 . ILE A 1 719 ? 133.091 155.145 115.421 1.00 44.56  ?  708 ILE A CG1 1 
ATOM   5316  C  CG2 . ILE A 1 719 ? 133.221 157.302 114.205 1.00 44.56  ?  708 ILE A CG2 1 
ATOM   5317  C  CD1 . ILE A 1 719 ? 133.696 155.630 116.682 1.00 44.56  ?  708 ILE A CD1 1 
ATOM   5318  N  N   . PHE A 1 720 ? 132.438 152.831 112.990 1.00 44.15  ?  709 PHE A N   1 
ATOM   5319  C  CA  . PHE A 1 720 ? 132.653 151.398 113.067 1.00 44.15  ?  709 PHE A CA  1 
ATOM   5320  C  C   . PHE A 1 720 ? 132.699 150.816 111.667 1.00 44.15  ?  709 PHE A C   1 
ATOM   5321  O  O   . PHE A 1 720 ? 131.802 151.059 110.859 1.00 44.15  ?  709 PHE A O   1 
ATOM   5322  C  CB  . PHE A 1 720 ? 131.566 150.735 113.901 1.00 44.15  ?  709 PHE A CB  1 
ATOM   5323  C  CG  . PHE A 1 720 ? 131.764 150.907 115.359 1.00 44.15  ?  709 PHE A CG  1 
ATOM   5324  C  CD1 . PHE A 1 720 ? 132.450 149.968 116.090 1.00 44.15  ?  709 PHE A CD1 1 
ATOM   5325  C  CD2 . PHE A 1 720 ? 131.292 152.026 115.999 1.00 44.15  ?  709 PHE A CD2 1 
ATOM   5326  C  CE1 . PHE A 1 720 ? 132.643 150.136 117.429 1.00 44.15  ?  709 PHE A CE1 1 
ATOM   5327  C  CE2 . PHE A 1 720 ? 131.489 152.196 117.331 1.00 44.15  ?  709 PHE A CE2 1 
ATOM   5328  C  CZ  . PHE A 1 720 ? 132.162 151.249 118.048 1.00 44.15  ?  709 PHE A CZ  1 
ATOM   5329  N  N   . PHE A 1 721 ? 133.756 150.074 111.380 1.00 40.91  ?  710 PHE A N   1 
ATOM   5330  C  CA  . PHE A 1 721 ? 133.933 149.372 110.126 1.00 40.91  ?  710 PHE A CA  1 
ATOM   5331  C  C   . PHE A 1 721 ? 134.150 147.901 110.420 1.00 40.91  ?  710 PHE A C   1 
ATOM   5332  O  O   . PHE A 1 721 ? 134.387 147.503 111.558 1.00 40.91  ?  710 PHE A O   1 
ATOM   5333  C  CB  . PHE A 1 721 ? 135.100 149.956 109.326 1.00 40.91  ?  710 PHE A CB  1 
ATOM   5334  C  CG  . PHE A 1 721 ? 134.713 151.120 108.493 1.00 40.91  ?  710 PHE A CG  1 
ATOM   5335  C  CD1 . PHE A 1 721 ? 134.596 150.999 107.136 1.00 40.91  ?  710 PHE A CD1 1 
ATOM   5336  C  CD2 . PHE A 1 721 ? 134.430 152.331 109.075 1.00 40.91  ?  710 PHE A CD2 1 
ATOM   5337  C  CE1 . PHE A 1 721 ? 134.219 152.059 106.380 1.00 40.91  ?  710 PHE A CE1 1 
ATOM   5338  C  CE2 . PHE A 1 721 ? 134.050 153.390 108.320 1.00 40.91  ?  710 PHE A CE2 1 
ATOM   5339  C  CZ  . PHE A 1 721 ? 133.946 153.255 106.973 1.00 40.91  ?  710 PHE A CZ  1 
ATOM   5340  N  N   . LEU A 1 722 ? 134.052 147.084 109.379 1.00 40.87  ?  711 LEU A N   1 
ATOM   5341  C  CA  . LEU A 1 722 ? 134.149 145.645 109.571 1.00 40.87  ?  711 LEU A CA  1 
ATOM   5342  C  C   . LEU A 1 722 ? 135.565 145.231 109.938 1.00 40.87  ?  711 LEU A C   1 
ATOM   5343  O  O   . LEU A 1 722 ? 135.786 144.572 110.956 1.00 40.87  ?  711 LEU A O   1 
ATOM   5344  C  CB  . LEU A 1 722 ? 133.679 144.916 108.318 1.00 40.87  ?  711 LEU A CB  1 
ATOM   5345  C  CG  . LEU A 1 722 ? 132.178 144.881 108.053 1.00 40.87  ?  711 LEU A CG  1 
ATOM   5346  C  CD1 . LEU A 1 722 ? 131.865 143.788 107.074 1.00 40.87  ?  711 LEU A CD1 1 
ATOM   5347  C  CD2 . LEU A 1 722 ? 131.412 144.676 109.331 1.00 40.87  ?  711 LEU A CD2 1 
ATOM   5348  N  N   . THR A 1 723 ? 136.538 145.601 109.117 1.00 38.92  ?  712 THR A N   1 
ATOM   5349  C  CA  . THR A 1 723 ? 137.916 145.166 109.275 1.00 38.92  ?  712 THR A CA  1 
ATOM   5350  C  C   . THR A 1 723 ? 138.837 146.366 109.127 1.00 38.92  ?  712 THR A C   1 
ATOM   5351  O  O   . THR A 1 723 ? 138.397 147.473 108.827 1.00 38.92  ?  712 THR A O   1 
ATOM   5352  C  CB  . THR A 1 723 ? 138.273 144.072 108.260 1.00 38.92  ?  712 THR A CB  1 
ATOM   5353  O  OG1 . THR A 1 723 ? 138.006 144.531 106.935 1.00 38.92  ?  712 THR A OG1 1 
ATOM   5354  C  CG2 . THR A 1 723 ? 137.462 142.832 108.510 1.00 38.92  ?  712 THR A CG2 1 
ATOM   5355  N  N   . ILE A 1 724 ? 140.132 146.140 109.347 1.00 36.63  ?  713 ILE A N   1 
ATOM   5356  C  CA  . ILE A 1 724 ? 141.117 147.193 109.136 1.00 36.63  ?  713 ILE A CA  1 
ATOM   5357  C  C   . ILE A 1 724 ? 141.166 147.591 107.673 1.00 36.63  ?  713 ILE A C   1 
ATOM   5358  O  O   . ILE A 1 724 ? 141.313 148.770 107.346 1.00 36.63  ?  713 ILE A O   1 
ATOM   5359  C  CB  . ILE A 1 724 ? 142.505 146.748 109.631 1.00 36.63  ?  713 ILE A CB  1 
ATOM   5360  C  CG1 . ILE A 1 724 ? 142.467 146.367 111.100 1.00 36.63  ?  713 ILE A CG1 1 
ATOM   5361  C  CG2 . ILE A 1 724 ? 143.522 147.836 109.418 1.00 36.63  ?  713 ILE A CG2 1 
ATOM   5362  C  CD1 . ILE A 1 724 ? 143.742 145.776 111.588 1.00 36.63  ?  713 ILE A CD1 1 
ATOM   5363  N  N   . HIS A 1 725 ? 141.051 146.624 106.769 1.00 37.38  ?  714 HIS A N   1 
ATOM   5364  C  CA  . HIS A 1 725 ? 141.153 146.938 105.354 1.00 37.38  ?  714 HIS A CA  1 
ATOM   5365  C  C   . HIS A 1 725 ? 139.942 147.711 104.858 1.00 37.38  ?  714 HIS A C   1 
ATOM   5366  O  O   . HIS A 1 725 ? 140.077 148.551 103.970 1.00 37.38  ?  714 HIS A O   1 
ATOM   5367  C  CB  . HIS A 1 725 ? 141.349 145.662 104.546 1.00 37.38  ?  714 HIS A CB  1 
ATOM   5368  C  CG  . HIS A 1 725 ? 141.994 145.891 103.221 1.00 37.38  ?  714 HIS A CG  1 
ATOM   5369  N  ND1 . HIS A 1 725 ? 141.454 145.432 102.044 1.00 37.38  ?  714 HIS A ND1 1 
ATOM   5370  C  CD2 . HIS A 1 725 ? 143.123 146.553 102.884 1.00 37.38  ?  714 HIS A CD2 1 
ATOM   5371  C  CE1 . HIS A 1 725 ? 142.228 145.793 101.039 1.00 37.38  ?  714 HIS A CE1 1 
ATOM   5372  N  NE2 . HIS A 1 725 ? 143.248 146.473 101.523 1.00 37.38  ?  714 HIS A NE2 1 
ATOM   5373  N  N   . ASP A 1 726 ? 138.764 147.455 105.421 1.00 40.57  ?  715 ASP A N   1 
ATOM   5374  C  CA  . ASP A 1 726 ? 137.593 148.263 105.102 1.00 40.57  ?  715 ASP A CA  1 
ATOM   5375  C  C   . ASP A 1 726 ? 137.833 149.724 105.437 1.00 40.57  ?  715 ASP A C   1 
ATOM   5376  O  O   . ASP A 1 726 ? 137.572 150.612 104.621 1.00 40.57  ?  715 ASP A O   1 
ATOM   5377  C  CB  . ASP A 1 726 ? 136.373 147.750 105.865 1.00 40.57  ?  715 ASP A CB  1 
ATOM   5378  C  CG  . ASP A 1 726 ? 135.832 146.467 105.309 1.00 40.57  ?  715 ASP A CG  1 
ATOM   5379  O  OD1 . ASP A 1 726 ? 136.219 145.400 105.810 1.00 40.57  ?  715 ASP A OD1 1 
ATOM   5380  O  OD2 . ASP A 1 726 ? 135.016 146.517 104.376 1.00 40.57  -1 715 ASP A OD2 1 
ATOM   5381  N  N   . ALA A 1 727 ? 138.333 149.990 106.641 1.00 40.04  ?  716 ALA A N   1 
ATOM   5382  C  CA  . ALA A 1 727 ? 138.600 151.359 107.051 1.00 40.04  ?  716 ALA A CA  1 
ATOM   5383  C  C   . ALA A 1 727 ? 139.697 151.986 106.208 1.00 40.04  ?  716 ALA A C   1 
ATOM   5384  O  O   . ALA A 1 727 ? 139.599 153.153 105.833 1.00 40.04  ?  716 ALA A O   1 
ATOM   5385  C  CB  . ALA A 1 727 ? 138.969 151.399 108.527 1.00 40.04  ?  716 ALA A CB  1 
ATOM   5386  N  N   . VAL A 1 728 ? 140.739 151.224 105.883 1.00 39.57  ?  717 VAL A N   1 
ATOM   5387  C  CA  . VAL A 1 728 ? 141.832 151.768 105.087 1.00 39.57  ?  717 VAL A CA  1 
ATOM   5388  C  C   . VAL A 1 728 ? 141.350 152.132 103.691 1.00 39.57  ?  717 VAL A C   1 
ATOM   5389  O  O   . VAL A 1 728 ? 141.691 153.193 103.166 1.00 39.57  ?  717 VAL A O   1 
ATOM   5390  C  CB  . VAL A 1 728 ? 143.008 150.775 105.046 1.00 39.57  ?  717 VAL A CB  1 
ATOM   5391  C  CG1 . VAL A 1 728 ? 143.974 151.143 103.957 1.00 39.57  ?  717 VAL A CG1 1 
ATOM   5392  C  CG2 . VAL A 1 728 ? 143.716 150.753 106.367 1.00 39.57  ?  717 VAL A CG2 1 
ATOM   5393  N  N   . LEU A 1 729 ? 140.542 151.273 103.073 1.00 41.84  ?  718 LEU A N   1 
ATOM   5394  C  CA  . LEU A 1 729 ? 140.049 151.564 101.734 1.00 41.84  ?  718 LEU A CA  1 
ATOM   5395  C  C   . LEU A 1 729 ? 139.074 152.729 101.746 1.00 41.84  ?  718 LEU A C   1 
ATOM   5396  O  O   . LEU A 1 729 ? 139.084 153.560 100.833 1.00 41.84  ?  718 LEU A O   1 
ATOM   5397  C  CB  . LEU A 1 729 ? 139.399 150.324 101.132 1.00 41.84  ?  718 LEU A CB  1 
ATOM   5398  C  CG  . LEU A 1 729 ? 140.346 149.173 100.816 1.00 41.84  ?  718 LEU A CG  1 
ATOM   5399  C  CD1 . LEU A 1 729 ? 139.570 147.989 100.317 1.00 41.84  ?  718 LEU A CD1 1 
ATOM   5400  C  CD2 . LEU A 1 729 ? 141.375 149.596 99.810  1.00 41.84  ?  718 LEU A CD2 1 
ATOM   5401  N  N   . HIS A 1 730 ? 138.237 152.817 102.779 1.00 44.21  ?  719 HIS A N   1 
ATOM   5402  C  CA  . HIS A 1 730 ? 137.361 153.972 102.926 1.00 44.21  ?  719 HIS A CA  1 
ATOM   5403  C  C   . HIS A 1 730 ? 138.163 155.259 103.058 1.00 44.21  ?  719 HIS A C   1 
ATOM   5404  O  O   . HIS A 1 730 ? 137.839 156.269 102.424 1.00 44.21  ?  719 HIS A O   1 
ATOM   5405  C  CB  . HIS A 1 730 ? 136.454 153.770 104.136 1.00 44.21  ?  719 HIS A CB  1 
ATOM   5406  C  CG  . HIS A 1 730 ? 135.588 154.945 104.450 1.00 44.21  ?  719 HIS A CG  1 
ATOM   5407  N  ND1 . HIS A 1 730 ? 134.381 155.162 103.828 1.00 44.21  ?  719 HIS A ND1 1 
ATOM   5408  C  CD2 . HIS A 1 730 ? 135.749 155.964 105.323 1.00 44.21  ?  719 HIS A CD2 1 
ATOM   5409  C  CE1 . HIS A 1 730 ? 133.837 156.266 104.303 1.00 44.21  ?  719 HIS A CE1 1 
ATOM   5410  N  NE2 . HIS A 1 730 ? 134.648 156.773 105.210 1.00 44.21  ?  719 HIS A NE2 1 
ATOM   5411  N  N   . ILE A 1 731 ? 139.219 155.236 103.867 1.00 46.27  ?  720 ILE A N   1 
ATOM   5412  C  CA  . ILE A 1 731 ? 140.072 156.406 104.038 1.00 46.27  ?  720 ILE A CA  1 
ATOM   5413  C  C   . ILE A 1 731 ? 140.716 156.793 102.717 1.00 46.27  ?  720 ILE A C   1 
ATOM   5414  O  O   . ILE A 1 731 ? 140.786 157.972 102.366 1.00 46.27  ?  720 ILE A O   1 
ATOM   5415  C  CB  . ILE A 1 731 ? 141.136 156.140 105.115 1.00 46.27  ?  720 ILE A CB  1 
ATOM   5416  C  CG1 . ILE A 1 731 ? 140.507 156.114 106.500 1.00 46.27  ?  720 ILE A CG1 1 
ATOM   5417  C  CG2 . ILE A 1 731 ? 142.227 157.165 105.041 1.00 46.27  ?  720 ILE A CG2 1 
ATOM   5418  C  CD1 . ILE A 1 731 ? 141.279 155.310 107.481 1.00 46.27  ?  720 ILE A CD1 1 
ATOM   5419  N  N   . LEU A 1 732 ? 141.214 155.807 101.975 1.00 51.62  ?  721 LEU A N   1 
ATOM   5420  C  CA  . LEU A 1 732 ? 141.879 156.110 100.716 1.00 51.62  ?  721 LEU A CA  1 
ATOM   5421  C  C   . LEU A 1 732 ? 140.913 156.693 99.702  1.00 51.62  ?  721 LEU A C   1 
ATOM   5422  O  O   . LEU A 1 732 ? 141.287 157.566 98.921  1.00 51.62  ?  721 LEU A O   1 
ATOM   5423  C  CB  . LEU A 1 732 ? 142.547 154.864 100.149 1.00 51.62  ?  721 LEU A CB  1 
ATOM   5424  C  CG  . LEU A 1 732 ? 143.690 154.292 100.975 1.00 51.62  ?  721 LEU A CG  1 
ATOM   5425  C  CD1 . LEU A 1 732 ? 144.216 153.032 100.339 1.00 51.62  ?  721 LEU A CD1 1 
ATOM   5426  C  CD2 . LEU A 1 732 ? 144.783 155.310 101.135 1.00 51.62  ?  721 LEU A CD2 1 
ATOM   5427  N  N   . MET A 1 733 ? 139.666 156.237 99.698  1.00 58.22  ?  722 MET A N   1 
ATOM   5428  C  CA  . MET A 1 733 ? 138.693 156.830 98.790  1.00 58.22  ?  722 MET A CA  1 
ATOM   5429  C  C   . MET A 1 733 ? 138.353 158.257 99.206  1.00 58.22  ?  722 MET A C   1 
ATOM   5430  O  O   . MET A 1 733 ? 138.228 159.151 98.359  1.00 58.22  ?  722 MET A O   1 
ATOM   5431  C  CB  . MET A 1 733 ? 137.449 155.951 98.725  1.00 58.22  ?  722 MET A CB  1 
ATOM   5432  C  CG  . MET A 1 733 ? 137.762 154.570 98.174  1.00 58.22  ?  722 MET A CG  1 
ATOM   5433  S  SD  . MET A 1 733 ? 136.496 153.293 98.346  1.00 58.22  ?  722 MET A SD  1 
ATOM   5434  C  CE  . MET A 1 733 ? 135.572 153.842 99.774  1.00 58.22  ?  722 MET A CE  1 
ATOM   5435  N  N   . LYS A 1 734 ? 138.217 158.494 100.510 1.00 61.33  ?  723 LYS A N   1 
ATOM   5436  C  CA  . LYS A 1 734 ? 138.008 159.852 101.002 1.00 61.33  ?  723 LYS A CA  1 
ATOM   5437  C  C   . LYS A 1 734 ? 139.147 160.776 100.590 1.00 61.33  ?  723 LYS A C   1 
ATOM   5438  O  O   . LYS A 1 734 ? 138.919 161.922 100.193 1.00 61.33  ?  723 LYS A O   1 
ATOM   5439  C  CB  . LYS A 1 734 ? 137.870 159.838 102.518 1.00 61.33  ?  723 LYS A CB  1 
ATOM   5440  C  CG  . LYS A 1 734 ? 136.487 159.542 103.007 1.00 61.33  ?  723 LYS A CG  1 
ATOM   5441  C  CD  . LYS A 1 734 ? 136.355 159.899 104.465 1.00 61.33  ?  723 LYS A CD  1 
ATOM   5442  C  CE  . LYS A 1 734 ? 136.769 161.330 104.706 1.00 61.33  ?  723 LYS A CE  1 
ATOM   5443  N  NZ  . LYS A 1 734 ? 136.415 161.784 106.072 1.00 61.33  1  723 LYS A NZ  1 
ATOM   5444  N  N   . LYS A 1 735 ? 140.384 160.294 100.671 1.00 66.80  ?  724 LYS A N   1 
ATOM   5445  C  CA  . LYS A 1 735 ? 141.516 161.148 100.337 1.00 66.80  ?  724 LYS A CA  1 
ATOM   5446  C  C   . LYS A 1 735 ? 141.660 161.307 98.830  1.00 66.80  ?  724 LYS A C   1 
ATOM   5447  O  O   . LYS A 1 735 ? 142.113 162.350 98.350  1.00 66.80  ?  724 LYS A O   1 
ATOM   5448  C  CB  . LYS A 1 735 ? 142.794 160.596 100.958 1.00 66.80  ?  724 LYS A CB  1 
ATOM   5449  C  CG  . LYS A 1 735 ? 142.759 160.607 102.463 1.00 66.80  ?  724 LYS A CG  1 
ATOM   5450  C  CD  . LYS A 1 735 ? 142.130 161.886 102.985 1.00 66.80  ?  724 LYS A CD  1 
ATOM   5451  C  CE  . LYS A 1 735 ? 141.395 161.643 104.289 1.00 66.80  ?  724 LYS A CE  1 
ATOM   5452  N  NZ  . LYS A 1 735 ? 141.010 162.902 104.982 1.00 66.80  1  724 LYS A NZ  1 
ATOM   5453  N  N   . ASP A 1 736 ? 141.260 160.294 98.062  1.00 75.61  ?  725 ASP A N   1 
ATOM   5454  C  CA  . ASP A 1 736 ? 141.178 160.478 96.620  1.00 75.61  ?  725 ASP A CA  1 
ATOM   5455  C  C   . ASP A 1 736 ? 140.193 161.576 96.268  1.00 75.61  ?  725 ASP A C   1 
ATOM   5456  O  O   . ASP A 1 736 ? 140.454 162.383 95.369  1.00 75.61  ?  725 ASP A O   1 
ATOM   5457  C  CB  . ASP A 1 736 ? 140.771 159.181 95.927  1.00 75.61  ?  725 ASP A CB  1 
ATOM   5458  C  CG  . ASP A 1 736 ? 141.941 158.245 95.697  1.00 75.61  ?  725 ASP A CG  1 
ATOM   5459  O  OD1 . ASP A 1 736 ? 141.861 157.066 96.100  1.00 75.61  ?  725 ASP A OD1 1 
ATOM   5460  O  OD2 . ASP A 1 736 ? 142.943 158.686 95.101  1.00 75.61  -1 725 ASP A OD2 1 
ATOM   5461  N  N   . ASN B 1 18  ? 133.307 152.182 95.974  1.00 56.06  ?  7   ASN B N   1 
ATOM   5462  C  CA  . ASN B 1 18  ? 133.961 151.388 97.003  1.00 56.06  ?  7   ASN B CA  1 
ATOM   5463  C  C   . ASN B 1 18  ? 134.010 149.918 96.626  1.00 56.06  ?  7   ASN B C   1 
ATOM   5464  O  O   . ASN B 1 18  ? 132.976 149.259 96.496  1.00 56.06  ?  7   ASN B O   1 
ATOM   5465  C  CB  . ASN B 1 18  ? 133.249 151.544 98.349  1.00 56.06  ?  7   ASN B CB  1 
ATOM   5466  C  CG  . ASN B 1 18  ? 131.760 151.255 98.277  1.00 56.06  ?  7   ASN B CG  1 
ATOM   5467  O  OD1 . ASN B 1 18  ? 131.201 151.048 97.202  1.00 56.06  ?  7   ASN B OD1 1 
ATOM   5468  N  ND2 . ASN B 1 18  ? 131.116 151.204 99.438  1.00 56.06  ?  7   ASN B ND2 1 
ATOM   5469  N  N   . GLN B 1 19  ? 135.215 149.371 96.493  1.00 47.27  ?  8   GLN B N   1 
ATOM   5470  C  CA  . GLN B 1 19  ? 135.314 147.935 96.243  1.00 47.27  ?  8   GLN B CA  1 
ATOM   5471  C  C   . GLN B 1 19  ? 136.483 147.304 96.977  1.00 47.27  ?  8   GLN B C   1 
ATOM   5472  O  O   . GLN B 1 19  ? 137.621 147.732 96.819  1.00 47.27  ?  8   GLN B O   1 
ATOM   5473  C  CB  . GLN B 1 19  ? 135.378 147.633 94.747  1.00 47.27  ?  8   GLN B CB  1 
ATOM   5474  C  CG  . GLN B 1 19  ? 134.997 146.206 94.389  1.00 47.27  ?  8   GLN B CG  1 
ATOM   5475  C  CD  . GLN B 1 19  ? 133.517 145.922 94.574  1.00 47.27  ?  8   GLN B CD  1 
ATOM   5476  O  OE1 . GLN B 1 19  ? 133.069 144.786 94.417  1.00 47.27  ?  8   GLN B OE1 1 
ATOM   5477  N  NE2 . GLN B 1 19  ? 132.750 146.956 94.902  1.00 47.27  ?  8   GLN B NE2 1 
ATOM   5478  N  N   . TYR B 1 20  ? 136.199 146.301 97.797  1.00 39.88  ?  9   TYR B N   1 
ATOM   5479  C  CA  . TYR B 1 20  ? 137.228 145.591 98.528  1.00 39.88  ?  9   TYR B CA  1 
ATOM   5480  C  C   . TYR B 1 20  ? 137.663 144.480 97.615  1.00 39.88  ?  9   TYR B C   1 
ATOM   5481  O  O   . TYR B 1 20  ? 136.926 143.524 97.408  1.00 39.88  ?  9   TYR B O   1 
ATOM   5482  C  CB  . TYR B 1 20  ? 136.620 145.087 99.827  1.00 39.88  ?  9   TYR B CB  1 
ATOM   5483  C  CG  . TYR B 1 20  ? 137.475 144.269 100.760 1.00 39.88  ?  9   TYR B CG  1 
ATOM   5484  C  CD1 . TYR B 1 20  ? 137.809 144.754 102.016 1.00 39.88  ?  9   TYR B CD1 1 
ATOM   5485  C  CD2 . TYR B 1 20  ? 137.886 142.989 100.422 1.00 39.88  ?  9   TYR B CD2 1 
ATOM   5486  C  CE1 . TYR B 1 20  ? 138.560 144.004 102.892 1.00 39.88  ?  9   TYR B CE1 1 
ATOM   5487  C  CE2 . TYR B 1 20  ? 138.641 142.233 101.293 1.00 39.88  ?  9   TYR B CE2 1 
ATOM   5488  C  CZ  . TYR B 1 20  ? 138.974 142.746 102.525 1.00 39.88  ?  9   TYR B CZ  1 
ATOM   5489  O  OH  . TYR B 1 20  ? 139.724 141.999 103.397 1.00 39.88  ?  9   TYR B OH  1 
ATOM   5490  N  N   . ILE B 1 21  ? 138.850 144.598 97.043  1.00 40.92  ?  10  ILE B N   1 
ATOM   5491  C  CA  . ILE B 1 21  ? 139.335 143.625 96.073  1.00 40.92  ?  10  ILE B CA  1 
ATOM   5492  C  C   . ILE B 1 21  ? 140.666 143.089 96.567  1.00 40.92  ?  10  ILE B C   1 
ATOM   5493  O  O   . ILE B 1 21  ? 141.643 143.835 96.679  1.00 40.92  ?  10  ILE B O   1 
ATOM   5494  C  CB  . ILE B 1 21  ? 139.467 144.234 94.675  1.00 40.92  ?  10  ILE B CB  1 
ATOM   5495  C  CG1 . ILE B 1 21  ? 138.099 144.633 94.154  1.00 40.92  ?  10  ILE B CG1 1 
ATOM   5496  C  CG2 . ILE B 1 21  ? 140.097 143.251 93.733  1.00 40.92  ?  10  ILE B CG2 1 
ATOM   5497  C  CD1 . ILE B 1 21  ? 138.156 145.413 92.899  1.00 40.92  ?  10  ILE B CD1 1 
ATOM   5498  N  N   . VAL B 1 22  ? 140.716 141.795 96.853  1.00 39.71  ?  11  VAL B N   1 
ATOM   5499  C  CA  . VAL B 1 22  ? 141.909 141.145 97.374  1.00 39.71  ?  11  VAL B CA  1 
ATOM   5500  C  C   . VAL B 1 22  ? 142.173 139.899 96.550  1.00 39.71  ?  11  VAL B C   1 
ATOM   5501  O  O   . VAL B 1 22  ? 141.244 139.158 96.225  1.00 39.71  ?  11  VAL B O   1 
ATOM   5502  C  CB  . VAL B 1 22  ? 141.754 140.786 98.863  1.00 39.71  ?  11  VAL B CB  1 
ATOM   5503  C  CG1 . VAL B 1 22  ? 142.936 139.995 99.345  1.00 39.71  ?  11  VAL B CG1 1 
ATOM   5504  C  CG2 . VAL B 1 22  ? 141.602 142.036 99.686  1.00 39.71  ?  11  VAL B CG2 1 
ATOM   5505  N  N   . ALA B 1 23  ? 143.434 139.677 96.199  1.00 41.12  ?  12  ALA B N   1 
ATOM   5506  C  CA  . ALA B 1 23  ? 143.867 138.440 95.554  1.00 41.12  ?  12  ALA B CA  1 
ATOM   5507  C  C   . ALA B 1 23  ? 145.220 138.083 96.155  1.00 41.12  ?  12  ALA B C   1 
ATOM   5508  O  O   . ALA B 1 23  ? 146.234 138.689 95.811  1.00 41.12  ?  12  ALA B O   1 
ATOM   5509  C  CB  . ALA B 1 23  ? 143.949 138.588 94.044  1.00 41.12  ?  12  ALA B CB  1 
ATOM   5510  N  N   . ARG B 1 24  ? 145.231 137.117 97.054  1.00 38.85  ?  13  ARG B N   1 
ATOM   5511  C  CA  . ARG B 1 24  ? 146.461 136.724 97.715  1.00 38.85  ?  13  ARG B CA  1 
ATOM   5512  C  C   . ARG B 1 24  ? 146.458 135.224 97.954  1.00 38.85  ?  13  ARG B C   1 
ATOM   5513  O  O   . ARG B 1 24  ? 145.441 134.568 97.719  1.00 38.85  ?  13  ARG B O   1 
ATOM   5514  C  CB  . ARG B 1 24  ? 146.625 137.487 99.026  1.00 38.85  ?  13  ARG B CB  1 
ATOM   5515  C  CG  . ARG B 1 24  ? 145.518 137.302 100.019 1.00 38.85  ?  13  ARG B CG  1 
ATOM   5516  C  CD  . ARG B 1 24  ? 146.025 137.714 101.350 1.00 38.85  ?  13  ARG B CD  1 
ATOM   5517  N  NE  . ARG B 1 24  ? 145.035 137.694 102.411 1.00 38.85  ?  13  ARG B NE  1 
ATOM   5518  C  CZ  . ARG B 1 24  ? 144.815 136.657 103.201 1.00 38.85  ?  13  ARG B CZ  1 
ATOM   5519  N  NH1 . ARG B 1 24  ? 145.493 135.542 103.032 1.00 38.85  1  13  ARG B NH1 1 
ATOM   5520  N  NH2 . ARG B 1 24  ? 143.916 136.737 104.158 1.00 38.85  ?  13  ARG B NH2 1 
ATOM   5521  N  N   . PRO B 1 25  ? 147.566 134.635 98.384  1.00 42.31  ?  14  PRO B N   1 
ATOM   5522  C  CA  . PRO B 1 25  ? 147.542 133.221 98.751  1.00 42.31  ?  14  PRO B CA  1 
ATOM   5523  C  C   . PRO B 1 25  ? 146.793 132.981 100.049 1.00 42.31  ?  14  PRO B C   1 
ATOM   5524  O  O   . PRO B 1 25  ? 146.603 133.874 100.872 1.00 42.31  ?  14  PRO B O   1 
ATOM   5525  C  CB  . PRO B 1 25  ? 149.022 132.863 98.892  1.00 42.31  ?  14  PRO B CB  1 
ATOM   5526  C  CG  . PRO B 1 25  ? 149.724 134.121 98.974  1.00 42.31  ?  14  PRO B CG  1 
ATOM   5527  C  CD  . PRO B 1 25  ? 148.942 135.129 98.248  1.00 42.31  ?  14  PRO B CD  1 
ATOM   5528  N  N   . VAL B 1 26  ? 146.355 131.745 100.245 1.00 43.57  ?  15  VAL B N   1 
ATOM   5529  C  CA  . VAL B 1 26  ? 145.728 131.394 101.502 1.00 43.57  ?  15  VAL B CA  1 
ATOM   5530  C  C   . VAL B 1 26  ? 146.889 131.185 102.439 1.00 43.57  ?  15  VAL B C   1 
ATOM   5531  O  O   . VAL B 1 26  ? 147.821 130.460 102.113 1.00 43.57  ?  15  VAL B O   1 
ATOM   5532  C  CB  . VAL B 1 26  ? 144.863 130.135 101.381 1.00 43.57  ?  15  VAL B CB  1 
ATOM   5533  C  CG1 . VAL B 1 26  ? 144.441 129.637 102.753 1.00 43.57  ?  15  VAL B CG1 1 
ATOM   5534  C  CG2 . VAL B 1 26  ? 143.657 130.405 100.499 1.00 43.57  ?  15  VAL B CG2 1 
ATOM   5535  N  N   . TYR B 1 27  ? 146.857 131.812 103.602 1.00 44.86  ?  16  TYR B N   1 
ATOM   5536  C  CA  . TYR B 1 27  ? 148.005 131.749 104.489 1.00 44.86  ?  16  TYR B CA  1 
ATOM   5537  C  C   . TYR B 1 27  ? 147.790 131.100 105.826 1.00 44.86  ?  16  TYR B C   1 
ATOM   5538  O  O   . TYR B 1 27  ? 146.902 131.488 106.571 1.00 44.86  ?  16  TYR B O   1 
ATOM   5539  C  CB  . TYR B 1 27  ? 148.505 133.168 104.767 1.00 44.86  ?  16  TYR B CB  1 
ATOM   5540  C  CG  . TYR B 1 27  ? 149.419 133.758 103.731 1.00 44.86  ?  16  TYR B CG  1 
ATOM   5541  C  CD1 . TYR B 1 27  ? 150.625 133.155 103.417 1.00 44.86  ?  16  TYR B CD1 1 
ATOM   5542  C  CD2 . TYR B 1 27  ? 149.096 134.948 103.098 1.00 44.86  ?  16  TYR B CD2 1 
ATOM   5543  C  CE1 . TYR B 1 27  ? 151.473 133.706 102.480 1.00 44.86  ?  16  TYR B CE1 1 
ATOM   5544  C  CE2 . TYR B 1 27  ? 149.937 135.507 102.162 1.00 44.86  ?  16  TYR B CE2 1 
ATOM   5545  C  CZ  . TYR B 1 27  ? 151.124 134.882 101.858 1.00 44.86  ?  16  TYR B CZ  1 
ATOM   5546  O  OH  . TYR B 1 27  ? 151.964 135.438 100.922 1.00 44.86  ?  16  TYR B OH  1 
ATOM   5547  N  N   . SER B 1 28  ? 148.603 130.107 106.140 1.00 47.64  ?  17  SER B N   1 
ATOM   5548  C  CA  . SER B 1 28  ? 148.566 129.530 107.453 1.00 47.64  ?  17  SER B CA  1 
ATOM   5549  C  C   . SER B 1 28  ? 149.564 130.403 108.161 1.00 47.64  ?  17  SER B C   1 
ATOM   5550  O  O   . SER B 1 28  ? 150.420 130.996 107.515 1.00 47.64  ?  17  SER B O   1 
ATOM   5551  C  CB  . SER B 1 28  ? 149.046 128.099 107.415 1.00 47.64  ?  17  SER B CB  1 
ATOM   5552  O  OG  . SER B 1 28  ? 149.091 127.545 108.715 1.00 47.64  ?  17  SER B OG  1 
ATOM   5553  N  N   . THR B 1 29  ? 149.488 130.516 109.474 1.00 49.54  ?  18  THR B N   1 
ATOM   5554  C  CA  . THR B 1 29  ? 150.390 131.425 110.168 1.00 49.54  ?  18  THR B CA  1 
ATOM   5555  C  C   . THR B 1 29  ? 151.847 131.046 109.892 1.00 49.54  ?  18  THR B C   1 
ATOM   5556  O  O   . THR B 1 29  ? 152.687 131.916 109.700 1.00 49.54  ?  18  THR B O   1 
ATOM   5557  C  CB  . THR B 1 29  ? 150.116 131.460 111.681 1.00 49.54  ?  18  THR B CB  1 
ATOM   5558  O  OG1 . THR B 1 29  ? 150.339 130.161 112.237 1.00 49.54  ?  18  THR B OG1 1 
ATOM   5559  C  CG2 . THR B 1 29  ? 148.687 131.886 111.947 1.00 49.54  ?  18  THR B CG2 1 
ATOM   5560  N  N   . ASN B 1 30  ? 152.147 129.754 109.851 1.00 51.74  ?  19  ASN B N   1 
ATOM   5561  C  CA  . ASN B 1 30  ? 153.501 129.295 109.543 1.00 51.74  ?  19  ASN B CA  1 
ATOM   5562  C  C   . ASN B 1 30  ? 153.924 129.652 108.129 1.00 51.74  ?  19  ASN B C   1 
ATOM   5563  O  O   . ASN B 1 30  ? 155.051 130.069 107.910 1.00 51.74  ?  19  ASN B O   1 
ATOM   5564  C  CB  . ASN B 1 30  ? 153.607 127.782 109.742 1.00 51.74  ?  19  ASN B CB  1 
ATOM   5565  C  CG  . ASN B 1 30  ? 153.556 127.378 111.199 1.00 51.74  ?  19  ASN B CG  1 
ATOM   5566  O  OD1 . ASN B 1 30  ? 153.580 128.222 112.091 1.00 51.74  ?  19  ASN B OD1 1 
ATOM   5567  N  ND2 . ASN B 1 30  ? 153.493 126.078 111.445 1.00 51.74  ?  19  ASN B ND2 1 
ATOM   5568  N  N   . ALA B 1 31  ? 153.025 129.492 107.169 1.00 51.04  ?  20  ALA B N   1 
ATOM   5569  C  CA  . ALA B 1 31  ? 153.327 129.834 105.786 1.00 51.04  ?  20  ALA B CA  1 
ATOM   5570  C  C   . ALA B 1 31  ? 153.585 131.322 105.609 1.00 51.04  ?  20  ALA B C   1 
ATOM   5571  O  O   . ALA B 1 31  ? 154.480 131.711 104.871 1.00 51.04  ?  20  ALA B O   1 
ATOM   5572  C  CB  . ALA B 1 31  ? 152.194 129.394 104.887 1.00 51.04  ?  20  ALA B CB  1 
ATOM   5573  N  N   . PHE B 1 32  ? 152.800 132.157 106.279 1.00 49.77  ?  21  PHE B N   1 
ATOM   5574  C  CA  . PHE B 1 32  ? 152.984 133.592 106.174 1.00 49.77  ?  21  PHE B CA  1 
ATOM   5575  C  C   . PHE B 1 32  ? 154.359 133.967 106.674 1.00 49.77  ?  21  PHE B C   1 
ATOM   5576  O  O   . PHE B 1 32  ? 155.026 134.810 106.089 1.00 49.77  ?  21  PHE B O   1 
ATOM   5577  C  CB  . PHE B 1 32  ? 151.921 134.343 106.970 1.00 49.77  ?  21  PHE B CB  1 
ATOM   5578  C  CG  . PHE B 1 32  ? 152.028 135.831 106.856 1.00 49.77  ?  21  PHE B CG  1 
ATOM   5579  C  CD1 . PHE B 1 32  ? 151.474 136.493 105.777 1.00 49.77  ?  21  PHE B CD1 1 
ATOM   5580  C  CD2 . PHE B 1 32  ? 152.692 136.567 107.822 1.00 49.77  ?  21  PHE B CD2 1 
ATOM   5581  C  CE1 . PHE B 1 32  ? 151.575 137.864 105.662 1.00 49.77  ?  21  PHE B CE1 1 
ATOM   5582  C  CE2 . PHE B 1 32  ? 152.796 137.939 107.714 1.00 49.77  ?  21  PHE B CE2 1 
ATOM   5583  C  CZ  . PHE B 1 32  ? 152.235 138.587 106.632 1.00 49.77  ?  21  PHE B CZ  1 
ATOM   5584  N  N   . GLU B 1 33  ? 154.783 133.339 107.762 1.00 56.20  ?  22  GLU B N   1 
ATOM   5585  C  CA  . GLU B 1 33  ? 156.094 133.625 108.314 1.00 56.20  ?  22  GLU B CA  1 
ATOM   5586  C  C   . GLU B 1 33  ? 157.176 133.114 107.386 1.00 56.20  ?  22  GLU B C   1 
ATOM   5587  O  O   . GLU B 1 33  ? 158.175 133.788 107.171 1.00 56.20  ?  22  GLU B O   1 
ATOM   5588  C  CB  . GLU B 1 33  ? 156.246 133.002 109.694 1.00 56.20  ?  22  GLU B CB  1 
ATOM   5589  C  CG  . GLU B 1 33  ? 155.109 133.320 110.650 1.00 56.20  ?  22  GLU B CG  1 
ATOM   5590  C  CD  . GLU B 1 33  ? 154.889 134.807 110.839 1.00 56.20  ?  22  GLU B CD  1 
ATOM   5591  O  OE1 . GLU B 1 33  ? 153.745 135.202 111.144 1.00 56.20  ?  22  GLU B OE1 1 
ATOM   5592  O  OE2 . GLU B 1 33  ? 155.854 135.582 110.679 1.00 56.20  -1 22  GLU B OE2 1 
ATOM   5593  N  N   . GLU B 1 34  ? 156.983 131.927 106.826 1.00 57.24  ?  23  GLU B N   1 
ATOM   5594  C  CA  . GLU B 1 34  ? 157.954 131.427 105.863 1.00 57.24  ?  23  GLU B CA  1 
ATOM   5595  C  C   . GLU B 1 34  ? 158.123 132.387 104.699 1.00 57.24  ?  23  GLU B C   1 
ATOM   5596  O  O   . GLU B 1 34  ? 159.225 132.528 104.161 1.00 57.24  ?  23  GLU B O   1 
ATOM   5597  C  CB  . GLU B 1 34  ? 157.533 130.054 105.348 1.00 57.24  ?  23  GLU B CB  1 
ATOM   5598  C  CG  . GLU B 1 34  ? 157.664 128.936 106.360 1.00 57.24  ?  23  GLU B CG  1 
ATOM   5599  C  CD  . GLU B 1 34  ? 156.829 127.722 105.998 1.00 57.24  ?  23  GLU B CD  1 
ATOM   5600  O  OE1 . GLU B 1 34  ? 156.394 127.622 104.833 1.00 57.24  ?  23  GLU B OE1 1 
ATOM   5601  O  OE2 . GLU B 1 34  ? 156.595 126.870 106.880 1.00 57.24  -1 23  GLU B OE2 1 
ATOM   5602  N  N   . ASN B 1 35  ? 157.045 133.047 104.286 1.00 55.92  ?  24  ASN B N   1 
ATOM   5603  C  CA  . ASN B 1 35  ? 157.123 133.868 103.085 1.00 55.92  ?  24  ASN B CA  1 
ATOM   5604  C  C   . ASN B 1 35  ? 157.509 135.306 103.396 1.00 55.92  ?  24  ASN B C   1 
ATOM   5605  O  O   . ASN B 1 35  ? 157.902 136.052 102.496 1.00 55.92  ?  24  ASN B O   1 
ATOM   5606  C  CB  . ASN B 1 35  ? 155.795 133.825 102.340 1.00 55.92  ?  24  ASN B CB  1 
ATOM   5607  C  CG  . ASN B 1 35  ? 155.620 132.552 101.556 1.00 55.92  ?  24  ASN B CG  1 
ATOM   5608  O  OD1 . ASN B 1 35  ? 156.055 132.456 100.412 1.00 55.92  ?  24  ASN B OD1 1 
ATOM   5609  N  ND2 . ASN B 1 35  ? 154.983 131.560 102.167 1.00 55.92  ?  24  ASN B ND2 1 
ATOM   5610  N  N   . HIS B 1 36  ? 157.393 135.721 104.647 1.00 55.14  ?  25  HIS B N   1 
ATOM   5611  C  CA  . HIS B 1 36  ? 157.675 137.093 105.029 1.00 55.14  ?  25  HIS B CA  1 
ATOM   5612  C  C   . HIS B 1 36  ? 158.707 137.116 106.136 1.00 55.14  ?  25  HIS B C   1 
ATOM   5613  O  O   . HIS B 1 36  ? 158.450 136.653 107.248 1.00 55.14  ?  25  HIS B O   1 
ATOM   5614  C  CB  . HIS B 1 36  ? 156.403 137.806 105.476 1.00 55.14  ?  25  HIS B CB  1 
ATOM   5615  C  CG  . HIS B 1 36  ? 155.384 137.924 104.394 1.00 55.14  ?  25  HIS B CG  1 
ATOM   5616  N  ND1 . HIS B 1 36  ? 154.483 136.924 104.110 1.00 55.14  ?  25  HIS B ND1 1 
ATOM   5617  C  CD2 . HIS B 1 36  ? 155.153 138.904 103.495 1.00 55.14  ?  25  HIS B CD2 1 
ATOM   5618  C  CE1 . HIS B 1 36  ? 153.726 137.293 103.096 1.00 55.14  ?  25  HIS B CE1 1 
ATOM   5619  N  NE2 . HIS B 1 36  ? 154.112 138.491 102.703 1.00 55.14  ?  25  HIS B NE2 1 
ATOM   5620  N  N   . LYS B 1 37  ? 159.876 137.660 105.826 1.00 63.84  ?  26  LYS B N   1 
ATOM   5621  C  CA  . LYS B 1 37  ? 160.971 137.605 106.771 1.00 63.84  ?  26  LYS B CA  1 
ATOM   5622  C  C   . LYS B 1 37  ? 160.660 138.469 107.988 1.00 63.84  ?  26  LYS B C   1 
ATOM   5623  O  O   . LYS B 1 37  ? 160.155 139.585 107.886 1.00 63.84  ?  26  LYS B O   1 
ATOM   5624  C  CB  . LYS B 1 37  ? 162.269 138.051 106.110 1.00 63.84  ?  26  LYS B CB  1 
ATOM   5625  C  CG  . LYS B 1 37  ? 163.498 137.552 106.834 1.00 63.84  ?  26  LYS B CG  1 
ATOM   5626  C  CD  . LYS B 1 37  ? 164.767 138.167 106.285 1.00 63.84  ?  26  LYS B CD  1 
ATOM   5627  C  CE  . LYS B 1 37  ? 165.706 138.539 107.415 1.00 63.84  ?  26  LYS B CE  1 
ATOM   5628  N  NZ  . LYS B 1 37  ? 165.756 137.477 108.461 1.00 63.84  1  26  LYS B NZ  1 
ATOM   5629  N  N   . LYS B 1 38  ? 160.985 137.931 109.156 1.00 64.44  ?  27  LYS B N   1 
ATOM   5630  C  CA  . LYS B 1 38  ? 160.680 138.564 110.431 1.00 64.44  ?  27  LYS B CA  1 
ATOM   5631  C  C   . LYS B 1 38  ? 161.899 139.368 110.843 1.00 64.44  ?  27  LYS B C   1 
ATOM   5632  O  O   . LYS B 1 38  ? 163.026 138.978 110.534 1.00 64.44  ?  27  LYS B O   1 
ATOM   5633  C  CB  . LYS B 1 38  ? 160.343 137.514 111.487 1.00 64.44  ?  27  LYS B CB  1 
ATOM   5634  C  CG  . LYS B 1 38  ? 159.470 138.004 112.614 1.00 64.44  ?  27  LYS B CG  1 
ATOM   5635  C  CD  . LYS B 1 38  ? 158.134 137.289 112.622 1.00 64.44  ?  27  LYS B CD  1 
ATOM   5636  C  CE  . LYS B 1 38  ? 157.329 137.663 113.850 1.00 64.44  ?  27  LYS B CE  1 
ATOM   5637  N  NZ  . LYS B 1 38  ? 156.118 136.819 113.980 1.00 64.44  1  27  LYS B NZ  1 
ATOM   5638  N  N   . THR B 1 39  ? 161.683 140.495 111.501 1.00 68.49  ?  28  THR B N   1 
ATOM   5639  C  CA  . THR B 1 39  ? 162.788 141.347 111.902 1.00 68.49  ?  28  THR B CA  1 
ATOM   5640  C  C   . THR B 1 39  ? 163.514 140.742 113.089 1.00 68.49  ?  28  THR B C   1 
ATOM   5641  O  O   . THR B 1 39  ? 163.168 139.659 113.549 1.00 68.49  ?  28  THR B O   1 
ATOM   5642  C  CB  . THR B 1 39  ? 162.301 142.762 112.256 1.00 68.49  ?  28  THR B CB  1 
ATOM   5643  O  OG1 . THR B 1 39  ? 161.341 142.687 113.314 1.00 68.49  ?  28  THR B OG1 1 
ATOM   5644  C  CG2 . THR B 1 39  ? 161.663 143.419 111.045 1.00 68.49  ?  28  THR B CG2 1 
ATOM   5645  N  N   . GLY B 1 40  ? 164.524 141.437 113.589 1.00 77.97  ?  29  GLY B N   1 
ATOM   5646  C  CA  . GLY B 1 40  ? 165.293 140.916 114.703 1.00 77.97  ?  29  GLY B CA  1 
ATOM   5647  C  C   . GLY B 1 40  ? 164.477 140.800 115.968 1.00 77.97  ?  29  GLY B C   1 
ATOM   5648  O  O   . GLY B 1 40  ? 163.986 141.798 116.493 1.00 77.97  ?  29  GLY B O   1 
ATOM   5649  N  N   . ARG B 1 41  ? 164.321 139.580 116.461 1.00 86.30  ?  30  ARG B N   1 
ATOM   5650  C  CA  . ARG B 1 41  ? 163.577 139.365 117.694 1.00 86.30  ?  30  ARG B CA  1 
ATOM   5651  C  C   . ARG B 1 41  ? 164.498 139.553 118.883 1.00 86.30  ?  30  ARG B C   1 
ATOM   5652  O  O   . ARG B 1 41  ? 164.941 138.580 119.489 1.00 86.30  ?  30  ARG B O   1 
ATOM   5653  C  CB  . ARG B 1 41  ? 162.973 137.964 117.715 1.00 86.30  ?  30  ARG B CB  1 
ATOM   5654  N  N   . HIS B 1 42  ? 164.797 140.803 119.218 1.00 105.03 ?  31  HIS B N   1 
ATOM   5655  C  CA  . HIS B 1 42  ? 165.697 141.081 120.326 1.00 105.03 ?  31  HIS B CA  1 
ATOM   5656  C  C   . HIS B 1 42  ? 165.007 140.903 121.666 1.00 105.03 ?  31  HIS B C   1 
ATOM   5657  O  O   . HIS B 1 42  ? 164.115 141.674 122.018 1.00 105.03 ?  31  HIS B O   1 
ATOM   5658  C  CB  . HIS B 1 42  ? 166.245 142.503 120.222 1.00 105.03 ?  31  HIS B CB  1 
ATOM   5659  C  CG  . HIS B 1 42  ? 166.916 142.978 121.473 1.00 105.03 ?  31  HIS B CG  1 
ATOM   5660  N  ND1 . HIS B 1 42  ? 166.258 143.710 122.437 1.00 105.03 ?  31  HIS B ND1 1 
ATOM   5661  C  CD2 . HIS B 1 42  ? 168.182 142.815 121.923 1.00 105.03 ?  31  HIS B CD2 1 
ATOM   5662  C  CE1 . HIS B 1 42  ? 167.091 143.984 123.425 1.00 105.03 ?  31  HIS B CE1 1 
ATOM   5663  N  NE2 . HIS B 1 42  ? 168.266 143.452 123.137 1.00 105.03 ?  31  HIS B NE2 1 
ATOM   5664  N  N   . HIS B 1 43  ? 165.422 139.892 122.417 1.00 114.83 ?  32  HIS B N   1 
ATOM   5665  C  CA  . HIS B 1 43  ? 164.844 139.661 123.735 1.00 114.83 ?  32  HIS B CA  1 
ATOM   5666  C  C   . HIS B 1 43  ? 165.358 140.675 124.741 1.00 114.83 ?  32  HIS B C   1 
ATOM   5667  O  O   . HIS B 1 43  ? 166.470 141.179 124.608 1.00 114.83 ?  32  HIS B O   1 
ATOM   5668  C  CB  . HIS B 1 43  ? 165.160 138.247 124.222 1.00 114.83 ?  32  HIS B CB  1 
ATOM   5669  C  CG  . HIS B 1 43  ? 165.017 138.077 125.702 1.00 114.83 ?  32  HIS B CG  1 
ATOM   5670  N  ND1 . HIS B 1 43  ? 163.793 137.940 126.320 1.00 114.83 ?  32  HIS B ND1 1 
ATOM   5671  C  CD2 . HIS B 1 43  ? 165.944 138.038 126.688 1.00 114.83 ?  32  HIS B CD2 1 
ATOM   5672  C  CE1 . HIS B 1 43  ? 163.972 137.816 127.623 1.00 114.83 ?  32  HIS B CE1 1 
ATOM   5673  N  NE2 . HIS B 1 43  ? 165.268 137.872 127.873 1.00 114.83 ?  32  HIS B NE2 1 
ATOM   5674  N  N   . LYS B 1 44  ? 164.552 140.975 125.753 1.00 120.44 ?  33  LYS B N   1 
ATOM   5675  C  CA  . LYS B 1 44  ? 164.973 141.916 126.786 1.00 120.44 ?  33  LYS B CA  1 
ATOM   5676  C  C   . LYS B 1 44  ? 165.312 141.165 128.061 1.00 120.44 ?  33  LYS B C   1 
ATOM   5677  O  O   . LYS B 1 44  ? 164.418 140.730 128.785 1.00 120.44 ?  33  LYS B O   1 
ATOM   5678  C  CB  . LYS B 1 44  ? 163.888 142.961 127.042 1.00 120.44 ?  33  LYS B CB  1 
ATOM   5679  N  N   . THR B 1 45  ? 166.601 141.011 128.341 1.00 130.75 ?  34  THR B N   1 
ATOM   5680  C  CA  . THR B 1 45  ? 167.025 140.247 129.513 1.00 130.75 ?  34  THR B CA  1 
ATOM   5681  C  C   . THR B 1 45  ? 166.813 141.001 130.815 1.00 130.75 ?  34  THR B C   1 
ATOM   5682  O  O   . THR B 1 45  ? 167.116 142.190 130.907 1.00 130.75 ?  34  THR B O   1 
ATOM   5683  C  CB  . THR B 1 45  ? 168.509 139.851 129.406 1.00 130.75 ?  34  THR B CB  1 
ATOM   5684  O  OG1 . THR B 1 45  ? 168.697 138.999 128.270 1.00 130.75 ?  34  THR B OG1 1 
ATOM   5685  C  CG2 . THR B 1 45  ? 168.963 139.123 130.661 1.00 130.75 ?  34  THR B CG2 1 
ATOM   5686  N  N   . PHE B 1 46  ? 166.302 140.306 131.825 1.00 133.01 ?  35  PHE B N   1 
ATOM   5687  C  CA  . PHE B 1 46  ? 166.080 140.933 133.118 1.00 133.01 ?  35  PHE B CA  1 
ATOM   5688  C  C   . PHE B 1 46  ? 167.383 141.482 133.663 1.00 133.01 ?  35  PHE B C   1 
ATOM   5689  O  O   . PHE B 1 46  ? 167.408 142.570 134.233 1.00 133.01 ?  35  PHE B O   1 
ATOM   5690  C  CB  . PHE B 1 46  ? 165.483 139.931 134.102 1.00 133.01 ?  35  PHE B CB  1 
ATOM   5691  C  CG  . PHE B 1 46  ? 165.369 140.456 135.502 1.00 133.01 ?  35  PHE B CG  1 
ATOM   5692  C  CD1 . PHE B 1 46  ? 164.270 141.203 135.887 1.00 133.01 ?  35  PHE B CD1 1 
ATOM   5693  C  CD2 . PHE B 1 46  ? 166.364 140.208 136.432 1.00 133.01 ?  35  PHE B CD2 1 
ATOM   5694  C  CE1 . PHE B 1 46  ? 164.162 141.691 137.175 1.00 133.01 ?  35  PHE B CE1 1 
ATOM   5695  C  CE2 . PHE B 1 46  ? 166.262 140.691 137.722 1.00 133.01 ?  35  PHE B CE2 1 
ATOM   5696  C  CZ  . PHE B 1 46  ? 165.160 141.434 138.094 1.00 133.01 ?  35  PHE B CZ  1 
ATOM   5697  N  N   . LEU B 1 47  ? 168.472 140.743 133.480 1.00 134.09 ?  36  LEU B N   1 
ATOM   5698  C  CA  . LEU B 1 47  ? 169.770 141.243 133.907 1.00 134.09 ?  36  LEU B CA  1 
ATOM   5699  C  C   . LEU B 1 47  ? 170.069 142.524 133.152 1.00 134.09 ?  36  LEU B C   1 
ATOM   5700  O  O   . LEU B 1 47  ? 170.639 143.460 133.708 1.00 134.09 ?  36  LEU B O   1 
ATOM   5701  C  CB  . LEU B 1 47  ? 170.864 140.204 133.658 1.00 134.09 ?  36  LEU B CB  1 
ATOM   5702  C  CG  . LEU B 1 47  ? 172.309 140.582 133.995 1.00 134.09 ?  36  LEU B CG  1 
ATOM   5703  C  CD1 . LEU B 1 47  ? 172.974 141.392 132.891 1.00 134.09 ?  36  LEU B CD1 1 
ATOM   5704  C  CD2 . LEU B 1 47  ? 172.406 141.287 135.339 1.00 134.09 ?  36  LEU B CD2 1 
ATOM   5705  N  N   . ASP B 1 48  ? 169.687 142.570 131.881 1.00 134.26 ?  37  ASP B N   1 
ATOM   5706  C  CA  . ASP B 1 48  ? 169.894 143.777 131.093 1.00 134.26 ?  37  ASP B CA  1 
ATOM   5707  C  C   . ASP B 1 48  ? 169.093 144.924 131.680 1.00 134.26 ?  37  ASP B C   1 
ATOM   5708  O  O   . ASP B 1 48  ? 169.562 146.060 131.708 1.00 134.26 ?  37  ASP B O   1 
ATOM   5709  C  CB  . ASP B 1 48  ? 169.501 143.548 129.636 1.00 134.26 ?  37  ASP B CB  1 
ATOM   5710  C  CG  . ASP B 1 48  ? 170.315 142.452 128.982 1.00 134.26 ?  37  ASP B CG  1 
ATOM   5711  O  OD1 . ASP B 1 48  ? 171.137 141.823 129.681 1.00 134.26 ?  37  ASP B OD1 1 
ATOM   5712  O  OD2 . ASP B 1 48  ? 170.130 142.215 127.770 1.00 134.26 -1 37  ASP B OD2 1 
ATOM   5713  N  N   . HIS B 1 49  ? 167.882 144.642 132.144 1.00 133.26 ?  38  HIS B N   1 
ATOM   5714  C  CA  . HIS B 1 49  ? 167.100 145.680 132.790 1.00 133.26 ?  38  HIS B CA  1 
ATOM   5715  C  C   . HIS B 1 49  ? 167.887 146.177 133.980 1.00 133.26 ?  38  HIS B C   1 
ATOM   5716  O  O   . HIS B 1 49  ? 167.966 147.375 134.229 1.00 133.26 ?  38  HIS B O   1 
ATOM   5717  C  CB  . HIS B 1 49  ? 165.750 145.145 133.254 1.00 133.26 ?  38  HIS B CB  1 
ATOM   5718  C  CG  . HIS B 1 49  ? 164.842 144.737 132.138 1.00 133.26 ?  38  HIS B CG  1 
ATOM   5719  N  ND1 . HIS B 1 49  ? 163.897 145.585 131.601 1.00 133.26 ?  38  HIS B ND1 1 
ATOM   5720  C  CD2 . HIS B 1 49  ? 164.729 143.570 131.462 1.00 133.26 ?  38  HIS B CD2 1 
ATOM   5721  C  CE1 . HIS B 1 49  ? 163.243 144.958 130.641 1.00 133.26 ?  38  HIS B CE1 1 
ATOM   5722  N  NE2 . HIS B 1 49  ? 163.729 143.734 130.534 1.00 133.26 ?  38  HIS B NE2 1 
ATOM   5723  N  N   . LEU B 1 50  ? 168.483 145.251 134.718 1.00 133.23 ?  39  LEU B N   1 
ATOM   5724  C  CA  . LEU B 1 50  ? 169.271 145.630 135.877 1.00 133.23 ?  39  LEU B CA  1 
ATOM   5725  C  C   . LEU B 1 50  ? 170.419 146.503 135.427 1.00 133.23 ?  39  LEU B C   1 
ATOM   5726  O  O   . LEU B 1 50  ? 170.758 147.480 136.089 1.00 133.23 ?  39  LEU B O   1 
ATOM   5727  C  CB  . LEU B 1 50  ? 169.798 144.391 136.591 1.00 133.23 ?  39  LEU B CB  1 
ATOM   5728  C  CG  . LEU B 1 50  ? 168.755 143.318 136.893 1.00 133.23 ?  39  LEU B CG  1 
ATOM   5729  C  CD1 . LEU B 1 50  ? 169.391 142.151 137.630 1.00 133.23 ?  39  LEU B CD1 1 
ATOM   5730  C  CD2 . LEU B 1 50  ? 167.602 143.905 137.691 1.00 133.23 ?  39  LEU B CD2 1 
ATOM   5731  N  N   . LYS B 1 51  ? 171.016 146.160 134.293 1.00 132.45 ?  40  LYS B N   1 
ATOM   5732  C  CA  . LYS B 1 51  ? 172.121 146.945 133.768 1.00 132.45 ?  40  LYS B CA  1 
ATOM   5733  C  C   . LYS B 1 51  ? 171.696 148.371 133.449 1.00 132.45 ?  40  LYS B C   1 
ATOM   5734  O  O   . LYS B 1 51  ? 172.381 149.326 133.811 1.00 132.45 ?  40  LYS B O   1 
ATOM   5735  C  CB  . LYS B 1 51  ? 172.681 146.285 132.509 1.00 132.45 ?  40  LYS B CB  1 
ATOM   5736  C  CG  . LYS B 1 51  ? 173.842 147.041 131.886 1.00 132.45 ?  40  LYS B CG  1 
ATOM   5737  C  CD  . LYS B 1 51  ? 174.976 147.217 132.882 1.00 132.45 ?  40  LYS B CD  1 
ATOM   5738  C  CE  . LYS B 1 51  ? 175.501 145.873 133.361 1.00 132.45 ?  40  LYS B CE  1 
ATOM   5739  N  NZ  . LYS B 1 51  ? 176.009 145.043 132.235 1.00 132.45 1  40  LYS B NZ  1 
ATOM   5740  N  N   . VAL B 1 52  ? 170.566 148.520 132.769 1.00 130.58 ?  41  VAL B N   1 
ATOM   5741  C  CA  . VAL B 1 52  ? 170.093 149.851 132.415 1.00 130.58 ?  41  VAL B CA  1 
ATOM   5742  C  C   . VAL B 1 52  ? 169.705 150.601 133.678 1.00 130.58 ?  41  VAL B C   1 
ATOM   5743  O  O   . VAL B 1 52  ? 169.939 151.803 133.784 1.00 130.58 ?  41  VAL B O   1 
ATOM   5744  C  CB  . VAL B 1 52  ? 168.913 149.811 131.421 1.00 130.58 ?  41  VAL B CB  1 
ATOM   5745  C  CG1 . VAL B 1 52  ? 169.255 148.929 130.231 1.00 130.58 ?  41  VAL B CG1 1 
ATOM   5746  C  CG2 . VAL B 1 52  ? 167.639 149.331 132.094 1.00 130.58 ?  41  VAL B CG2 1 
ATOM   5747  N  N   . CYS B 1 53  ? 169.119 149.897 134.641 1.00 130.88 ?  42  CYS B N   1 
ATOM   5748  C  CA  . CYS B 1 53  ? 168.765 150.527 135.903 1.00 130.88 ?  42  CYS B CA  1 
ATOM   5749  C  C   . CYS B 1 53  ? 170.030 150.931 136.629 1.00 130.88 ?  42  CYS B C   1 
ATOM   5750  O  O   . CYS B 1 53  ? 170.038 151.900 137.385 1.00 130.88 ?  42  CYS B O   1 
ATOM   5751  C  CB  . CYS B 1 53  ? 167.937 149.583 136.772 1.00 130.88 ?  42  CYS B CB  1 
ATOM   5752  S  SG  . CYS B 1 53  ? 166.329 149.142 136.078 1.00 130.88 ?  42  CYS B SG  1 
ATOM   5753  N  N   . CYS B 1 54  ? 171.103 150.185 136.404 1.00 127.49 ?  43  CYS B N   1 
ATOM   5754  C  CA  . CYS B 1 54  ? 172.361 150.485 137.066 1.00 127.49 ?  43  CYS B CA  1 
ATOM   5755  C  C   . CYS B 1 54  ? 173.261 151.253 136.125 1.00 127.49 ?  43  CYS B C   1 
ATOM   5756  O  O   . CYS B 1 54  ? 174.270 150.731 135.655 1.00 127.49 ?  43  CYS B O   1 
ATOM   5757  C  CB  . CYS B 1 54  ? 173.046 149.200 137.530 1.00 127.49 ?  43  CYS B CB  1 
ATOM   5758  S  SG  . CYS B 1 54  ? 174.515 149.470 138.548 1.00 127.49 ?  43  CYS B SG  1 
ATOM   5759  N  N   . SER B 1 55  ? 172.894 152.493 135.839 1.00 121.55 ?  44  SER B N   1 
ATOM   5760  C  CA  . SER B 1 55  ? 173.692 153.317 134.942 1.00 121.55 ?  44  SER B CA  1 
ATOM   5761  C  C   . SER B 1 55  ? 174.510 154.340 135.714 1.00 121.55 ?  44  SER B C   1 
ATOM   5762  O  O   . SER B 1 55  ? 175.626 154.670 135.316 1.00 121.55 ?  44  SER B O   1 
ATOM   5763  C  CB  . SER B 1 55  ? 172.796 154.027 133.929 1.00 121.55 ?  44  SER B CB  1 
ATOM   5764  O  OG  . SER B 1 55  ? 173.512 155.030 133.230 1.00 121.55 ?  44  SER B OG  1 
ATOM   5765  N  N   . CYS B 1 56  ? 173.947 154.898 136.775 1.00 117.51 ?  45  CYS B N   1 
ATOM   5766  C  CA  . CYS B 1 56  ? 174.650 155.907 137.572 1.00 117.51 ?  45  CYS B CA  1 
ATOM   5767  C  C   . CYS B 1 56  ? 175.438 156.923 136.745 1.00 117.51 ?  45  CYS B C   1 
ATOM   5768  O  O   . CYS B 1 56  ? 176.569 157.258 137.092 1.00 117.51 ?  45  CYS B O   1 
ATOM   5769  C  CB  . CYS B 1 56  ? 175.585 155.224 138.575 1.00 117.51 ?  45  CYS B CB  1 
ATOM   5770  S  SG  . CYS B 1 56  ? 176.213 156.309 139.879 1.00 117.51 ?  45  CYS B SG  1 
ATOM   5771  N  N   . SER B 1 57  ? 174.862 157.419 135.656 1.00 111.96 ?  46  SER B N   1 
ATOM   5772  C  CA  . SER B 1 57  ? 175.537 158.463 134.888 1.00 111.96 ?  46  SER B CA  1 
ATOM   5773  C  C   . SER B 1 57  ? 175.346 159.812 135.580 1.00 111.96 ?  46  SER B C   1 
ATOM   5774  O  O   . SER B 1 57  ? 174.363 160.014 136.293 1.00 111.96 ?  46  SER B O   1 
ATOM   5775  C  CB  . SER B 1 57  ? 175.015 158.522 133.455 1.00 111.96 ?  46  SER B CB  1 
ATOM   5776  O  OG  . SER B 1 57  ? 173.710 159.067 133.409 1.00 111.96 ?  46  SER B OG  1 
ATOM   5777  N  N   . PRO B 1 58  ? 176.287 160.743 135.376 1.00 109.85 ?  47  PRO B N   1 
ATOM   5778  C  CA  . PRO B 1 58  ? 176.191 162.035 136.066 1.00 109.85 ?  47  PRO B CA  1 
ATOM   5779  C  C   . PRO B 1 58  ? 174.872 162.717 135.757 1.00 109.85 ?  47  PRO B C   1 
ATOM   5780  O  O   . PRO B 1 58  ? 174.218 163.227 136.668 1.00 109.85 ?  47  PRO B O   1 
ATOM   5781  C  CB  . PRO B 1 58  ? 177.347 162.840 135.469 1.00 109.85 ?  47  PRO B CB  1 
ATOM   5782  C  CG  . PRO B 1 58  ? 178.311 161.815 134.974 1.00 109.85 ?  47  PRO B CG  1 
ATOM   5783  C  CD  . PRO B 1 58  ? 177.477 160.656 134.515 1.00 109.85 ?  47  PRO B CD  1 
ATOM   5784  N  N   . GLN B 1 59  ? 174.474 162.717 134.492 1.00 107.17 ?  48  GLN B N   1 
ATOM   5785  C  CA  . GLN B 1 59  ? 173.193 163.298 134.124 1.00 107.17 ?  48  GLN B CA  1 
ATOM   5786  C  C   . GLN B 1 59  ? 172.048 162.533 134.777 1.00 107.17 ?  48  GLN B C   1 
ATOM   5787  O  O   . GLN B 1 59  ? 171.064 163.131 135.208 1.00 107.17 ?  48  GLN B O   1 
ATOM   5788  C  CB  . GLN B 1 59  ? 173.018 163.306 132.608 1.00 107.17 ?  48  GLN B CB  1 
ATOM   5789  C  CG  . GLN B 1 59  ? 173.066 161.926 131.975 1.00 107.17 ?  48  GLN B CG  1 
ATOM   5790  C  CD  . GLN B 1 59  ? 172.669 161.943 130.513 1.00 107.17 ?  48  GLN B CD  1 
ATOM   5791  O  OE1 . GLN B 1 59  ? 172.604 160.900 129.864 1.00 107.17 ?  48  GLN B OE1 1 
ATOM   5792  N  NE2 . GLN B 1 59  ? 172.395 163.132 129.988 1.00 107.17 ?  48  GLN B NE2 1 
ATOM   5793  N  N   . LYS B 1 60  ? 172.173 161.212 134.852 1.00 105.09 ?  49  LYS B N   1 
ATOM   5794  C  CA  . LYS B 1 60  ? 171.118 160.410 135.445 1.00 105.09 ?  49  LYS B CA  1 
ATOM   5795  C  C   . LYS B 1 60  ? 170.970 160.792 136.903 1.00 105.09 ?  49  LYS B C   1 
ATOM   5796  O  O   . LYS B 1 60  ? 169.863 160.899 137.416 1.00 105.09 ?  49  LYS B O   1 
ATOM   5797  C  CB  . LYS B 1 60  ? 171.414 158.917 135.321 1.00 105.09 ?  49  LYS B CB  1 
ATOM   5798  C  CG  . LYS B 1 60  ? 170.175 158.048 135.443 1.00 105.09 ?  49  LYS B CG  1 
ATOM   5799  C  CD  . LYS B 1 60  ? 170.509 156.567 135.498 1.00 105.09 ?  49  LYS B CD  1 
ATOM   5800  C  CE  . LYS B 1 60  ? 171.026 156.173 136.871 1.00 105.09 ?  49  LYS B CE  1 
ATOM   5801  N  NZ  . LYS B 1 60  ? 171.065 154.695 137.037 1.00 105.09 1  49  LYS B NZ  1 
ATOM   5802  N  N   . ALA B 1 61  ? 172.091 161.003 137.577 1.00 98.88  ?  50  ALA B N   1 
ATOM   5803  C  CA  . ALA B 1 61  ? 172.040 161.388 138.974 1.00 98.88  ?  50  ALA B CA  1 
ATOM   5804  C  C   . ALA B 1 61  ? 171.278 162.692 139.115 1.00 98.88  ?  50  ALA B C   1 
ATOM   5805  O  O   . ALA B 1 61  ? 170.431 162.834 139.993 1.00 98.88  ?  50  ALA B O   1 
ATOM   5806  C  CB  . ALA B 1 61  ? 173.441 161.526 139.536 1.00 98.88  ?  50  ALA B CB  1 
ATOM   5807  N  N   . LYS B 1 62  ? 171.569 163.644 138.240 1.00 95.35  ?  51  LYS B N   1 
ATOM   5808  C  CA  . LYS B 1 62  ? 170.894 164.926 138.311 1.00 95.35  ?  51  LYS B CA  1 
ATOM   5809  C  C   . LYS B 1 62  ? 169.400 164.737 138.145 1.00 95.35  ?  51  LYS B C   1 
ATOM   5810  O  O   . LYS B 1 62  ? 168.608 165.332 138.873 1.00 95.35  ?  51  LYS B O   1 
ATOM   5811  C  CB  . LYS B 1 62  ? 171.415 165.873 137.238 1.00 95.35  ?  51  LYS B CB  1 
ATOM   5812  C  CG  . LYS B 1 62  ? 170.690 167.207 137.198 1.00 95.35  ?  51  LYS B CG  1 
ATOM   5813  C  CD  . LYS B 1 62  ? 171.157 168.057 136.030 1.00 95.35  ?  51  LYS B CD  1 
ATOM   5814  C  CE  . LYS B 1 62  ? 170.410 169.378 135.980 1.00 95.35  ?  51  LYS B CE  1 
ATOM   5815  N  NZ  . LYS B 1 62  ? 170.815 170.203 134.809 1.00 95.35  1  51  LYS B NZ  1 
ATOM   5816  N  N   . ARG B 1 63  ? 169.006 163.902 137.193 1.00 94.17  ?  52  ARG B N   1 
ATOM   5817  C  CA  . ARG B 1 63  ? 167.589 163.712 136.942 1.00 94.17  ?  52  ARG B CA  1 
ATOM   5818  C  C   . ARG B 1 63  ? 166.924 163.090 138.161 1.00 94.17  ?  52  ARG B C   1 
ATOM   5819  O  O   . ARG B 1 63  ? 165.829 163.492 138.542 1.00 94.17  ?  52  ARG B O   1 
ATOM   5820  C  CB  . ARG B 1 63  ? 167.350 162.871 135.685 1.00 94.17  ?  52  ARG B CB  1 
ATOM   5821  C  CG  . ARG B 1 63  ? 167.517 161.375 135.854 1.00 94.17  ?  52  ARG B CG  1 
ATOM   5822  C  CD  . ARG B 1 63  ? 167.090 160.641 134.595 1.00 94.17  ?  52  ARG B CD  1 
ATOM   5823  N  NE  . ARG B 1 63  ? 167.365 159.212 134.681 1.00 94.17  ?  52  ARG B NE  1 
ATOM   5824  C  CZ  . ARG B 1 63  ? 166.531 158.321 135.203 1.00 94.17  ?  52  ARG B CZ  1 
ATOM   5825  N  NH1 . ARG B 1 63  ? 166.867 157.039 135.240 1.00 94.17  1  52  ARG B NH1 1 
ATOM   5826  N  NH2 . ARG B 1 63  ? 165.361 158.711 135.689 1.00 94.17  ?  52  ARG B NH2 1 
ATOM   5827  N  N   . ILE B 1 64  ? 167.594 162.134 138.792 1.00 88.16  ?  53  ILE B N   1 
ATOM   5828  C  CA  . ILE B 1 64  ? 167.028 161.478 139.964 1.00 88.16  ?  53  ILE B CA  1 
ATOM   5829  C  C   . ILE B 1 64  ? 166.842 162.439 141.128 1.00 88.16  ?  53  ILE B C   1 
ATOM   5830  O  O   . ILE B 1 64  ? 165.788 162.454 141.757 1.00 88.16  ?  53  ILE B O   1 
ATOM   5831  C  CB  . ILE B 1 64  ? 167.905 160.308 140.436 1.00 88.16  ?  53  ILE B CB  1 
ATOM   5832  C  CG1 . ILE B 1 64  ? 168.083 159.295 139.306 1.00 88.16  ?  53  ILE B CG1 1 
ATOM   5833  C  CG2 . ILE B 1 64  ? 167.296 159.645 141.661 1.00 88.16  ?  53  ILE B CG2 1 
ATOM   5834  C  CD1 . ILE B 1 64  ? 166.779 158.810 138.715 1.00 88.16  ?  53  ILE B CD1 1 
ATOM   5835  N  N   . VAL B 1 65  ? 167.861 163.239 141.420 1.00 83.65  ?  54  VAL B N   1 
ATOM   5836  C  CA  . VAL B 1 65  ? 167.779 164.166 142.544 1.00 83.65  ?  54  VAL B CA  1 
ATOM   5837  C  C   . VAL B 1 65  ? 166.757 165.256 142.270 1.00 83.65  ?  54  VAL B C   1 
ATOM   5838  O  O   . VAL B 1 65  ? 166.028 165.662 143.166 1.00 83.65  ?  54  VAL B O   1 
ATOM   5839  C  CB  . VAL B 1 65  ? 169.145 164.795 142.877 1.00 83.65  ?  54  VAL B CB  1 
ATOM   5840  C  CG1 . VAL B 1 65  ? 170.149 163.712 143.235 1.00 83.65  ?  54  VAL B CG1 1 
ATOM   5841  C  CG2 . VAL B 1 65  ? 169.653 165.634 141.717 1.00 83.65  ?  54  VAL B CG2 1 
ATOM   5842  N  N   . LEU B 1 66  ? 166.694 165.727 141.033 1.00 80.39  ?  55  LEU B N   1 
ATOM   5843  C  CA  . LEU B 1 66  ? 165.707 166.733 140.682 1.00 80.39  ?  55  LEU B CA  1 
ATOM   5844  C  C   . LEU B 1 66  ? 164.323 166.127 140.750 1.00 80.39  ?  55  LEU B C   1 
ATOM   5845  O  O   . LEU B 1 66  ? 163.347 166.825 141.009 1.00 80.39  ?  55  LEU B O   1 
ATOM   5846  C  CB  . LEU B 1 66  ? 165.973 167.291 139.285 1.00 80.39  ?  55  LEU B CB  1 
ATOM   5847  C  CG  . LEU B 1 66  ? 166.860 168.533 139.204 1.00 80.39  ?  55  LEU B CG  1 
ATOM   5848  C  CD1 . LEU B 1 66  ? 168.128 168.372 140.027 1.00 80.39  ?  55  LEU B CD1 1 
ATOM   5849  C  CD2 . LEU B 1 66  ? 167.186 168.863 137.757 1.00 80.39  ?  55  LEU B CD2 1 
ATOM   5850  N  N   . SER B 1 67  ? 164.235 164.822 140.549 1.00 74.04  ?  56  SER B N   1 
ATOM   5851  C  CA  . SER B 1 67  ? 162.952 164.153 140.633 1.00 74.04  ?  56  SER B CA  1 
ATOM   5852  C  C   . SER B 1 67  ? 162.498 164.054 142.075 1.00 74.04  ?  56  SER B C   1 
ATOM   5853  O  O   . SER B 1 67  ? 161.303 164.099 142.351 1.00 74.04  ?  56  SER B O   1 
ATOM   5854  C  CB  . SER B 1 67  ? 163.042 162.763 140.016 1.00 74.04  ?  56  SER B CB  1 
ATOM   5855  O  OG  . SER B 1 67  ? 161.802 162.087 140.092 1.00 74.04  ?  56  SER B OG  1 
ATOM   5856  N  N   . LEU B 1 68  ? 163.441 163.922 142.998 1.00 67.25  ?  57  LEU B N   1 
ATOM   5857  C  CA  . LEU B 1 68  ? 163.103 163.774 144.406 1.00 67.25  ?  57  LEU B CA  1 
ATOM   5858  C  C   . LEU B 1 68  ? 162.978 165.111 145.098 1.00 67.25  ?  57  LEU B C   1 
ATOM   5859  O  O   . LEU B 1 68  ? 162.471 165.185 146.212 1.00 67.25  ?  57  LEU B O   1 
ATOM   5860  C  CB  . LEU B 1 68  ? 164.160 162.929 145.101 1.00 67.25  ?  57  LEU B CB  1 
ATOM   5861  C  CG  . LEU B 1 68  ? 164.360 161.530 144.526 1.00 67.25  ?  57  LEU B CG  1 
ATOM   5862  C  CD1 . LEU B 1 68  ? 165.504 160.825 145.236 1.00 67.25  ?  57  LEU B CD1 1 
ATOM   5863  C  CD2 . LEU B 1 68  ? 163.075 160.725 144.633 1.00 67.25  ?  57  LEU B CD2 1 
ATOM   5864  N  N   . PHE B 1 69  ? 163.436 166.169 144.444 1.00 63.89  ?  58  PHE B N   1 
ATOM   5865  C  CA  . PHE B 1 69  ? 163.321 167.508 144.998 1.00 63.89  ?  58  PHE B CA  1 
ATOM   5866  C  C   . PHE B 1 69  ? 162.798 168.398 143.906 1.00 63.89  ?  58  PHE B C   1 
ATOM   5867  O  O   . PHE B 1 69  ? 163.539 169.199 143.353 1.00 63.89  ?  58  PHE B O   1 
ATOM   5868  C  CB  . PHE B 1 69  ? 164.664 168.015 145.500 1.00 63.89  ?  58  PHE B CB  1 
ATOM   5869  C  CG  . PHE B 1 69  ? 165.198 167.255 146.673 1.00 63.89  ?  58  PHE B CG  1 
ATOM   5870  C  CD1 . PHE B 1 69  ? 165.982 166.131 146.486 1.00 63.89  ?  58  PHE B CD1 1 
ATOM   5871  C  CD2 . PHE B 1 69  ? 164.919 167.667 147.963 1.00 63.89  ?  58  PHE B CD2 1 
ATOM   5872  C  CE1 . PHE B 1 69  ? 166.477 165.428 147.567 1.00 63.89  ?  58  PHE B CE1 1 
ATOM   5873  C  CE2 . PHE B 1 69  ? 165.412 166.971 149.048 1.00 63.89  ?  58  PHE B CE2 1 
ATOM   5874  C  CZ  . PHE B 1 69  ? 166.191 165.849 148.851 1.00 63.89  ?  58  PHE B CZ  1 
ATOM   5875  N  N   . PRO B 1 70  ? 161.510 168.268 143.591 1.00 59.92  ?  59  PRO B N   1 
ATOM   5876  C  CA  . PRO B 1 70  ? 160.949 169.028 142.473 1.00 59.92  ?  59  PRO B CA  1 
ATOM   5877  C  C   . PRO B 1 70  ? 161.145 170.526 142.616 1.00 59.92  ?  59  PRO B C   1 
ATOM   5878  O  O   . PRO B 1 70  ? 161.225 171.216 141.606 1.00 59.92  ?  59  PRO B O   1 
ATOM   5879  C  CB  . PRO B 1 70  ? 159.461 168.683 142.545 1.00 59.92  ?  59  PRO B CB  1 
ATOM   5880  C  CG  . PRO B 1 70  ? 159.407 167.357 143.224 1.00 59.92  ?  59  PRO B CG  1 
ATOM   5881  C  CD  . PRO B 1 70  ? 160.510 167.399 144.234 1.00 59.92  ?  59  PRO B CD  1 
ATOM   5882  N  N   . ILE B 1 71  ? 161.219 171.026 143.838 1.00 58.88  ?  60  ILE B N   1 
ATOM   5883  C  CA  . ILE B 1 71  ? 161.331 172.462 144.055 1.00 58.88  ?  60  ILE B CA  1 
ATOM   5884  C  C   . ILE B 1 71  ? 162.571 173.033 143.387 1.00 58.88  ?  60  ILE B C   1 
ATOM   5885  O  O   . ILE B 1 71  ? 162.555 174.160 142.904 1.00 58.88  ?  60  ILE B O   1 
ATOM   5886  C  CB  . ILE B 1 71  ? 161.324 172.797 145.563 1.00 58.88  ?  60  ILE B CB  1 
ATOM   5887  C  CG1 . ILE B 1 71  ? 161.159 174.305 145.773 1.00 58.88  ?  60  ILE B CG1 1 
ATOM   5888  C  CG2 . ILE B 1 71  ? 162.582 172.276 146.242 1.00 58.88  ?  60  ILE B CG2 1 
ATOM   5889  C  CD1 . ILE B 1 71  ? 160.853 174.689 147.203 1.00 58.88  ?  60  ILE B CD1 1 
ATOM   5890  N  N   . ALA B 1 72  ? 163.642 172.254 143.345 1.00 61.87  ?  61  ALA B N   1 
ATOM   5891  C  CA  . ALA B 1 72  ? 164.876 172.710 142.726 1.00 61.87  ?  61  ALA B CA  1 
ATOM   5892  C  C   . ALA B 1 72  ? 164.682 172.906 141.241 1.00 61.87  ?  61  ALA B C   1 
ATOM   5893  O  O   . ALA B 1 72  ? 165.535 173.472 140.568 1.00 61.87  ?  61  ALA B O   1 
ATOM   5894  C  CB  . ALA B 1 72  ? 165.987 171.715 142.987 1.00 61.87  ?  61  ALA B CB  1 
ATOM   5895  N  N   . SER B 1 73  ? 163.560 172.433 140.724 1.00 63.13  ?  62  SER B N   1 
ATOM   5896  C  CA  . SER B 1 73  ? 163.277 172.580 139.309 1.00 63.13  ?  62  SER B CA  1 
ATOM   5897  C  C   . SER B 1 73  ? 162.260 173.671 139.023 1.00 63.13  ?  62  SER B C   1 
ATOM   5898  O  O   . SER B 1 73  ? 162.440 174.452 138.093 1.00 63.13  ?  62  SER B O   1 
ATOM   5899  C  CB  . SER B 1 73  ? 162.766 171.257 138.747 1.00 63.13  ?  62  SER B CB  1 
ATOM   5900  O  OG  . SER B 1 73  ? 163.695 170.213 138.978 1.00 63.13  ?  62  SER B OG  1 
ATOM   5901  N  N   . TRP B 1 74  ? 161.196 173.743 139.814 1.00 58.98  ?  63  TRP B N   1 
ATOM   5902  C  CA  . TRP B 1 74  ? 160.137 174.706 139.523 1.00 58.98  ?  63  TRP B CA  1 
ATOM   5903  C  C   . TRP B 1 74  ? 160.329 176.081 140.150 1.00 58.98  ?  63  TRP B C   1 
ATOM   5904  O  O   . TRP B 1 74  ? 159.761 177.060 139.675 1.00 58.98  ?  63  TRP B O   1 
ATOM   5905  C  CB  . TRP B 1 74  ? 158.768 174.137 139.915 1.00 58.98  ?  63  TRP B CB  1 
ATOM   5906  C  CG  . TRP B 1 74  ? 158.526 173.923 141.380 1.00 58.98  ?  63  TRP B CG  1 
ATOM   5907  C  CD1 . TRP B 1 74  ? 158.635 172.749 142.063 1.00 58.98  ?  63  TRP B CD1 1 
ATOM   5908  C  CD2 . TRP B 1 74  ? 158.089 174.900 142.333 1.00 58.98  ?  63  TRP B CD2 1 
ATOM   5909  N  NE1 . TRP B 1 74  ? 158.313 172.937 143.383 1.00 58.98  ?  63  TRP B NE1 1 
ATOM   5910  C  CE2 . TRP B 1 74  ? 157.974 174.250 143.575 1.00 58.98  ?  63  TRP B CE2 1 
ATOM   5911  C  CE3 . TRP B 1 74  ? 157.792 176.264 142.257 1.00 58.98  ?  63  TRP B CE3 1 
ATOM   5912  C  CZ2 . TRP B 1 74  ? 157.578 174.915 144.732 1.00 58.98  ?  63  TRP B CZ2 1 
ATOM   5913  C  CZ3 . TRP B 1 74  ? 157.402 176.921 143.405 1.00 58.98  ?  63  TRP B CZ3 1 
ATOM   5914  C  CH2 . TRP B 1 74  ? 157.298 176.247 144.626 1.00 58.98  ?  63  TRP B CH2 1 
ATOM   5915  N  N   . LEU B 1 75  ? 161.110 176.165 141.214 1.00 61.28  ?  64  LEU B N   1 
ATOM   5916  C  CA  . LEU B 1 75  ? 161.281 177.445 141.884 1.00 61.28  ?  64  LEU B CA  1 
ATOM   5917  C  C   . LEU B 1 75  ? 162.074 178.434 141.029 1.00 61.28  ?  64  LEU B C   1 
ATOM   5918  O  O   . LEU B 1 75  ? 161.659 179.576 140.860 1.00 61.28  ?  64  LEU B O   1 
ATOM   5919  C  CB  . LEU B 1 75  ? 161.950 177.272 143.246 1.00 61.28  ?  64  LEU B CB  1 
ATOM   5920  C  CG  . LEU B 1 75  ? 161.988 178.525 144.116 1.00 61.28  ?  64  LEU B CG  1 
ATOM   5921  C  CD1 . LEU B 1 75  ? 160.576 179.041 144.346 1.00 61.28  ?  64  LEU B CD1 1 
ATOM   5922  C  CD2 . LEU B 1 75  ? 162.677 178.229 145.437 1.00 61.28  ?  64  LEU B CD2 1 
ATOM   5923  N  N   . PRO B 1 76  ? 163.215 177.993 140.477 1.00 63.39  ?  65  PRO B N   1 
ATOM   5924  C  CA  . PRO B 1 76  ? 164.030 178.881 139.645 1.00 63.39  ?  65  PRO B CA  1 
ATOM   5925  C  C   . PRO B 1 76  ? 163.261 179.392 138.433 1.00 63.39  ?  65  PRO B C   1 
ATOM   5926  O  O   . PRO B 1 76  ? 163.564 180.469 137.928 1.00 63.39  ?  65  PRO B O   1 
ATOM   5927  C  CB  . PRO B 1 76  ? 165.168 177.973 139.195 1.00 63.39  ?  65  PRO B CB  1 
ATOM   5928  C  CG  . PRO B 1 76  ? 165.279 176.948 140.267 1.00 63.39  ?  65  PRO B CG  1 
ATOM   5929  C  CD  . PRO B 1 76  ? 163.865 176.685 140.675 1.00 63.39  ?  65  PRO B CD  1 
ATOM   5930  N  N   . ALA B 1 77  ? 162.280 178.632 137.975 1.00 64.49  ?  66  ALA B N   1 
ATOM   5931  C  CA  . ALA B 1 77  ? 161.495 179.034 136.821 1.00 64.49  ?  66  ALA B CA  1 
ATOM   5932  C  C   . ALA B 1 77  ? 160.259 179.814 137.226 1.00 64.49  ?  66  ALA B C   1 
ATOM   5933  O  O   . ALA B 1 77  ? 159.310 179.909 136.455 1.00 64.49  ?  66  ALA B O   1 
ATOM   5934  C  CB  . ALA B 1 77  ? 161.094 177.807 136.030 1.00 64.49  ?  66  ALA B CB  1 
ATOM   5935  N  N   . TYR B 1 78  ? 160.261 180.378 138.428 1.00 64.83  ?  67  TYR B N   1 
ATOM   5936  C  CA  . TYR B 1 78  ? 159.075 181.076 138.916 1.00 64.83  ?  67  TYR B CA  1 
ATOM   5937  C  C   . TYR B 1 78  ? 158.872 182.401 138.212 1.00 64.83  ?  67  TYR B C   1 
ATOM   5938  O  O   . TYR B 1 78  ? 159.800 183.193 138.093 1.00 64.83  ?  67  TYR B O   1 
ATOM   5939  C  CB  . TYR B 1 78  ? 159.160 181.303 140.423 1.00 64.83  ?  67  TYR B CB  1 
ATOM   5940  C  CG  . TYR B 1 78  ? 157.853 181.733 141.046 1.00 64.83  ?  67  TYR B CG  1 
ATOM   5941  C  CD1 . TYR B 1 78  ? 156.975 180.799 141.574 1.00 64.83  ?  67  TYR B CD1 1 
ATOM   5942  C  CD2 . TYR B 1 78  ? 157.496 183.072 141.102 1.00 64.83  ?  67  TYR B CD2 1 
ATOM   5943  C  CE1 . TYR B 1 78  ? 155.779 181.188 142.142 1.00 64.83  ?  67  TYR B CE1 1 
ATOM   5944  C  CE2 . TYR B 1 78  ? 156.302 183.469 141.667 1.00 64.83  ?  67  TYR B CE2 1 
ATOM   5945  C  CZ  . TYR B 1 78  ? 155.449 182.522 142.187 1.00 64.83  ?  67  TYR B CZ  1 
ATOM   5946  O  OH  . TYR B 1 78  ? 154.261 182.914 142.752 1.00 64.83  ?  67  TYR B OH  1 
ATOM   5947  N  N   . ARG B 1 79  ? 157.656 182.646 137.749 1.00 70.95  ?  68  ARG B N   1 
ATOM   5948  C  CA  . ARG B 1 79  ? 157.360 183.895 137.077 1.00 70.95  ?  68  ARG B CA  1 
ATOM   5949  C  C   . ARG B 1 79  ? 156.806 184.894 138.077 1.00 70.95  ?  68  ARG B C   1 
ATOM   5950  O  O   . ARG B 1 79  ? 155.594 185.051 138.198 1.00 70.95  ?  68  ARG B O   1 
ATOM   5951  C  CB  . ARG B 1 79  ? 156.385 183.643 135.936 1.00 70.95  ?  68  ARG B CB  1 
ATOM   5952  C  CG  . ARG B 1 79  ? 156.850 182.533 135.006 1.00 70.95  ?  68  ARG B CG  1 
ATOM   5953  C  CD  . ARG B 1 79  ? 156.027 182.457 133.732 1.00 70.95  ?  68  ARG B CD  1 
ATOM   5954  N  NE  . ARG B 1 79  ? 154.656 182.025 133.981 1.00 70.95  ?  68  ARG B NE  1 
ATOM   5955  C  CZ  . ARG B 1 79  ? 153.745 181.847 133.031 1.00 70.95  ?  68  ARG B CZ  1 
ATOM   5956  N  NH1 . ARG B 1 79  ? 152.520 181.452 133.348 1.00 70.95  1  68  ARG B NH1 1 
ATOM   5957  N  NH2 . ARG B 1 79  ? 154.057 182.071 131.762 1.00 70.95  ?  68  ARG B NH2 1 
ATOM   5958  N  N   . LEU B 1 80  ? 157.691 185.589 138.782 1.00 70.91  ?  69  LEU B N   1 
ATOM   5959  C  CA  . LEU B 1 80  ? 157.260 186.524 139.820 1.00 70.91  ?  69  LEU B CA  1 
ATOM   5960  C  C   . LEU B 1 80  ? 156.249 187.542 139.340 1.00 70.91  ?  69  LEU B C   1 
ATOM   5961  O  O   . LEU B 1 80  ? 155.279 187.825 140.034 1.00 70.91  ?  69  LEU B O   1 
ATOM   5962  C  CB  . LEU B 1 80  ? 158.471 187.263 140.390 1.00 70.91  ?  69  LEU B CB  1 
ATOM   5963  C  CG  . LEU B 1 80  ? 159.376 186.458 141.319 1.00 70.91  ?  69  LEU B CG  1 
ATOM   5964  C  CD1 . LEU B 1 80  ? 160.638 187.243 141.638 1.00 70.91  ?  69  LEU B CD1 1 
ATOM   5965  C  CD2 . LEU B 1 80  ? 158.628 186.099 142.593 1.00 70.91  ?  69  LEU B CD2 1 
ATOM   5966  N  N   . LYS B 1 81  ? 156.466 188.100 138.162 1.00 75.41  ?  70  LYS B N   1 
ATOM   5967  C  CA  . LYS B 1 81  ? 155.574 189.128 137.651 1.00 75.41  ?  70  LYS B CA  1 
ATOM   5968  C  C   . LYS B 1 81  ? 154.169 188.619 137.435 1.00 75.41  ?  70  LYS B C   1 
ATOM   5969  O  O   . LYS B 1 81  ? 153.208 189.339 137.685 1.00 75.41  ?  70  LYS B O   1 
ATOM   5970  C  CB  . LYS B 1 81  ? 156.111 189.658 136.327 1.00 75.41  ?  70  LYS B CB  1 
ATOM   5971  C  CG  . LYS B 1 81  ? 157.527 190.202 136.406 1.00 75.41  ?  70  LYS B CG  1 
ATOM   5972  C  CD  . LYS B 1 81  ? 158.249 190.020 135.081 1.00 75.41  ?  70  LYS B CD  1 
ATOM   5973  C  CE  . LYS B 1 81  ? 157.394 190.498 133.919 1.00 75.41  ?  70  LYS B CE  1 
ATOM   5974  N  NZ  . LYS B 1 81  ? 158.038 190.210 132.608 1.00 75.41  1  70  LYS B NZ  1 
ATOM   5975  N  N   . GLU B 1 82  ? 154.034 187.383 136.980 1.00 74.66  ?  71  GLU B N   1 
ATOM   5976  C  CA  . GLU B 1 82  ? 152.712 186.861 136.650 1.00 74.66  ?  71  GLU B CA  1 
ATOM   5977  C  C   . GLU B 1 82  ? 152.060 185.982 137.714 1.00 74.66  ?  71  GLU B C   1 
ATOM   5978  O  O   . GLU B 1 82  ? 150.866 185.703 137.630 1.00 74.66  ?  71  GLU B O   1 
ATOM   5979  C  CB  . GLU B 1 82  ? 152.833 186.072 135.352 1.00 74.66  ?  71  GLU B CB  1 
ATOM   5980  C  CG  . GLU B 1 82  ? 153.693 186.784 134.321 1.00 74.66  ?  71  GLU B CG  1 
ATOM   5981  C  CD  . GLU B 1 82  ? 154.248 185.845 133.274 1.00 74.66  ?  71  GLU B CD  1 
ATOM   5982  O  OE1 . GLU B 1 82  ? 153.958 184.637 133.353 1.00 74.66  ?  71  GLU B OE1 1 
ATOM   5983  O  OE2 . GLU B 1 82  ? 154.971 186.316 132.372 1.00 74.66  -1 71  GLU B OE2 1 
ATOM   5984  N  N   . TRP B 1 83  ? 152.821 185.542 138.710 1.00 66.39  ?  72  TRP B N   1 
ATOM   5985  C  CA  . TRP B 1 83  ? 152.269 184.614 139.694 1.00 66.39  ?  72  TRP B CA  1 
ATOM   5986  C  C   . TRP B 1 83  ? 152.285 185.090 141.132 1.00 66.39  ?  72  TRP B C   1 
ATOM   5987  O  O   . TRP B 1 83  ? 151.360 184.798 141.880 1.00 66.39  ?  72  TRP B O   1 
ATOM   5988  C  CB  . TRP B 1 83  ? 153.052 183.308 139.656 1.00 66.39  ?  72  TRP B CB  1 
ATOM   5989  C  CG  . TRP B 1 83  ? 152.981 182.554 138.383 1.00 66.39  ?  72  TRP B CG  1 
ATOM   5990  C  CD1 . TRP B 1 83  ? 152.073 182.708 137.379 1.00 66.39  ?  72  TRP B CD1 1 
ATOM   5991  C  CD2 . TRP B 1 83  ? 153.850 181.495 137.981 1.00 66.39  ?  72  TRP B CD2 1 
ATOM   5992  N  NE1 . TRP B 1 83  ? 152.331 181.814 136.371 1.00 66.39  ?  72  TRP B NE1 1 
ATOM   5993  C  CE2 . TRP B 1 83  ? 153.418 181.057 136.718 1.00 66.39  ?  72  TRP B CE2 1 
ATOM   5994  C  CE3 . TRP B 1 83  ? 154.957 180.877 138.568 1.00 66.39  ?  72  TRP B CE3 1 
ATOM   5995  C  CZ2 . TRP B 1 83  ? 154.053 180.027 136.031 1.00 66.39  ?  72  TRP B CZ2 1 
ATOM   5996  C  CZ3 . TRP B 1 83  ? 155.587 179.860 137.885 1.00 66.39  ?  72  TRP B CZ3 1 
ATOM   5997  C  CH2 . TRP B 1 83  ? 155.135 179.445 136.630 1.00 66.39  ?  72  TRP B CH2 1 
ATOM   5998  N  N   . LEU B 1 84  ? 153.320 185.810 141.538 1.00 63.56  ?  73  LEU B N   1 
ATOM   5999  C  CA  . LEU B 1 84  ? 153.439 186.179 142.951 1.00 63.56  ?  73  LEU B CA  1 
ATOM   6000  C  C   . LEU B 1 84  ? 152.125 186.635 143.569 1.00 63.56  ?  73  LEU B C   1 
ATOM   6001  O  O   . LEU B 1 84  ? 151.661 186.032 144.529 1.00 63.56  ?  73  LEU B O   1 
ATOM   6002  C  CB  . LEU B 1 84  ? 154.508 187.253 143.145 1.00 63.56  ?  73  LEU B CB  1 
ATOM   6003  C  CG  . LEU B 1 84  ? 154.899 187.493 144.599 1.00 63.56  ?  73  LEU B CG  1 
ATOM   6004  C  CD1 . LEU B 1 84  ? 155.367 186.193 145.234 1.00 63.56  ?  73  LEU B CD1 1 
ATOM   6005  C  CD2 . LEU B 1 84  ? 155.979 188.556 144.688 1.00 63.56  ?  73  LEU B CD2 1 
ATOM   6006  N  N   . LEU B 1 85  ? 151.513 187.674 143.022 1.00 59.74  ?  74  LEU B N   1 
ATOM   6007  C  CA  . LEU B 1 85  ? 150.288 188.202 143.606 1.00 59.74  ?  74  LEU B CA  1 
ATOM   6008  C  C   . LEU B 1 85  ? 149.182 187.167 143.620 1.00 59.74  ?  74  LEU B C   1 
ATOM   6009  O  O   . LEU B 1 85  ? 148.446 187.061 144.596 1.00 59.74  ?  74  LEU B O   1 
ATOM   6010  C  CB  . LEU B 1 85  ? 149.823 189.449 142.857 1.00 59.74  ?  74  LEU B CB  1 
ATOM   6011  C  CG  . LEU B 1 85  ? 148.557 190.095 143.415 1.00 59.74  ?  74  LEU B CG  1 
ATOM   6012  C  CD1 . LEU B 1 85  ? 148.772 190.510 144.861 1.00 59.74  ?  74  LEU B CD1 1 
ATOM   6013  C  CD2 . LEU B 1 85  ? 148.142 191.286 142.567 1.00 59.74  ?  74  LEU B CD2 1 
ATOM   6014  N  N   . SER B 1 86  ? 149.060 186.400 142.545 1.00 56.85  ?  75  SER B N   1 
ATOM   6015  C  CA  . SER B 1 86  ? 148.017 185.389 142.462 1.00 56.85  ?  75  SER B CA  1 
ATOM   6016  C  C   . SER B 1 86  ? 148.205 184.341 143.537 1.00 56.85  ?  75  SER B C   1 
ATOM   6017  O  O   . SER B 1 86  ? 147.253 183.961 144.209 1.00 56.85  ?  75  SER B O   1 
ATOM   6018  C  CB  . SER B 1 86  ? 148.027 184.732 141.085 1.00 56.85  ?  75  SER B CB  1 
ATOM   6019  O  OG  . SER B 1 86  ? 147.812 185.685 140.062 1.00 56.85  ?  75  SER B OG  1 
ATOM   6020  N  N   . ASP B 1 87  ? 149.433 183.875 143.707 1.00 55.69  ?  76  ASP B N   1 
ATOM   6021  C  CA  . ASP B 1 87  ? 149.727 182.888 144.742 1.00 55.69  ?  76  ASP B CA  1 
ATOM   6022  C  C   . ASP B 1 87  ? 149.491 183.449 146.137 1.00 55.69  ?  76  ASP B C   1 
ATOM   6023  O  O   . ASP B 1 87  ? 149.053 182.736 147.031 1.00 55.69  ?  76  ASP B O   1 
ATOM   6024  C  CB  . ASP B 1 87  ? 151.162 182.385 144.604 1.00 55.69  ?  76  ASP B CB  1 
ATOM   6025  C  CG  . ASP B 1 87  ? 151.282 181.238 143.630 1.00 55.69  ?  76  ASP B CG  1 
ATOM   6026  O  OD1 . ASP B 1 87  ? 150.249 180.615 143.320 1.00 55.69  ?  76  ASP B OD1 1 
ATOM   6027  O  OD2 . ASP B 1 87  ? 152.408 180.951 143.182 1.00 55.69  -1 76  ASP B OD2 1 
ATOM   6028  N  N   . ILE B 1 88  ? 149.776 184.727 146.322 1.00 54.08  ?  77  ILE B N   1 
ATOM   6029  C  CA  . ILE B 1 88  ? 149.550 185.356 147.611 1.00 54.08  ?  77  ILE B CA  1 
ATOM   6030  C  C   . ILE B 1 88  ? 148.069 185.388 147.959 1.00 54.08  ?  77  ILE B C   1 
ATOM   6031  O  O   . ILE B 1 88  ? 147.688 185.042 149.070 1.00 54.08  ?  77  ILE B O   1 
ATOM   6032  C  CB  . ILE B 1 88  ? 150.130 186.779 147.639 1.00 54.08  ?  77  ILE B CB  1 
ATOM   6033  C  CG1 . ILE B 1 88  ? 151.642 186.736 147.430 1.00 54.08  ?  77  ILE B CG1 1 
ATOM   6034  C  CG2 . ILE B 1 88  ? 149.801 187.466 148.954 1.00 54.08  ?  77  ILE B CG2 1 
ATOM   6035  C  CD1 . ILE B 1 88  ? 152.278 188.102 147.309 1.00 54.08  ?  77  ILE B CD1 1 
ATOM   6036  N  N   . VAL B 1 89  ? 147.233 185.786 147.012 1.00 52.56  ?  78  VAL B N   1 
ATOM   6037  C  CA  . VAL B 1 89  ? 145.791 185.827 147.244 1.00 52.56  ?  78  VAL B CA  1 
ATOM   6038  C  C   . VAL B 1 89  ? 145.225 184.434 147.452 1.00 52.56  ?  78  VAL B C   1 
ATOM   6039  O  O   . VAL B 1 89  ? 144.413 184.219 148.347 1.00 52.56  ?  78  VAL B O   1 
ATOM   6040  C  CB  . VAL B 1 89  ? 145.064 186.500 146.069 1.00 52.56  ?  78  VAL B CB  1 
ATOM   6041  C  CG1 . VAL B 1 89  ? 143.561 186.484 146.292 1.00 52.56  ?  78  VAL B CG1 1 
ATOM   6042  C  CG2 . VAL B 1 89  ? 145.570 187.919 145.880 1.00 52.56  ?  78  VAL B CG2 1 
ATOM   6043  N  N   . SER B 1 90  ? 145.639 183.484 146.627 1.00 51.39  ?  79  SER B N   1 
ATOM   6044  C  CA  . SER B 1 90  ? 145.194 182.114 146.788 1.00 51.39  ?  79  SER B CA  1 
ATOM   6045  C  C   . SER B 1 90  ? 145.652 181.567 148.123 1.00 51.39  ?  79  SER B C   1 
ATOM   6046  O  O   . SER B 1 90  ? 144.923 180.829 148.773 1.00 51.39  ?  79  SER B O   1 
ATOM   6047  C  CB  . SER B 1 90  ? 145.738 181.253 145.657 1.00 51.39  ?  79  SER B CB  1 
ATOM   6048  O  OG  . SER B 1 90  ? 145.442 179.888 145.869 1.00 51.39  ?  79  SER B OG  1 
ATOM   6049  N  N   . GLY B 1 91  ? 146.859 181.923 148.538 1.00 50.34  ?  80  GLY B N   1 
ATOM   6050  C  CA  . GLY B 1 91  ? 147.394 181.434 149.789 1.00 50.34  ?  80  GLY B CA  1 
ATOM   6051  C  C   . GLY B 1 91  ? 146.636 181.909 150.995 1.00 50.34  ?  80  GLY B C   1 
ATOM   6052  O  O   . GLY B 1 91  ? 146.325 181.125 151.882 1.00 50.34  ?  80  GLY B O   1 
ATOM   6053  N  N   . ILE B 1 92  ? 146.319 183.196 151.043 1.00 49.92  ?  81  ILE B N   1 
ATOM   6054  C  CA  . ILE B 1 92  ? 145.570 183.764 152.149 1.00 49.92  ?  81  ILE B CA  1 
ATOM   6055  C  C   . ILE B 1 92  ? 144.189 183.134 152.213 1.00 49.92  ?  81  ILE B C   1 
ATOM   6056  O  O   . ILE B 1 92  ? 143.701 182.812 153.282 1.00 49.92  ?  81  ILE B O   1 
ATOM   6057  C  CB  . ILE B 1 92  ? 145.388 185.279 152.003 1.00 49.92  ?  81  ILE B CB  1 
ATOM   6058  C  CG1 . ILE B 1 92  ? 146.711 185.970 151.688 1.00 49.92  ?  81  ILE B CG1 1 
ATOM   6059  C  CG2 . ILE B 1 92  ? 144.785 185.864 153.265 1.00 49.92  ?  81  ILE B CG2 1 
ATOM   6060  C  CD1 . ILE B 1 92  ? 147.279 186.770 152.827 1.00 49.92  ?  81  ILE B CD1 1 
ATOM   6061  N  N   . SER B 1 93  ? 143.557 182.955 151.061 1.00 50.51  ?  82  SER B N   1 
ATOM   6062  C  CA  . SER B 1 93  ? 142.238 182.352 151.018 1.00 50.51  ?  82  SER B CA  1 
ATOM   6063  C  C   . SER B 1 93  ? 142.272 180.909 151.488 1.00 50.51  ?  82  SER B C   1 
ATOM   6064  O  O   . SER B 1 93  ? 141.441 180.493 152.292 1.00 50.51  ?  82  SER B O   1 
ATOM   6065  C  CB  . SER B 1 93  ? 141.690 182.425 149.598 1.00 50.51  ?  82  SER B CB  1 
ATOM   6066  O  OG  . SER B 1 93  ? 141.749 183.747 149.096 1.00 50.51  ?  82  SER B OG  1 
ATOM   6067  N  N   . THR B 1 94  ? 143.234 180.144 150.995 1.00 49.73  ?  83  THR B N   1 
ATOM   6068  C  CA  . THR B 1 94  ? 143.347 178.744 151.373 1.00 49.73  ?  83  THR B CA  1 
ATOM   6069  C  C   . THR B 1 94  ? 143.781 178.616 152.823 1.00 49.73  ?  83  THR B C   1 
ATOM   6070  O  O   . THR B 1 94  ? 143.349 177.709 153.521 1.00 49.73  ?  83  THR B O   1 
ATOM   6071  C  CB  . THR B 1 94  ? 144.331 177.998 150.453 1.00 49.73  ?  83  THR B CB  1 
ATOM   6072  O  OG1 . THR B 1 94  ? 144.126 178.415 149.100 1.00 49.73  ?  83  THR B OG1 1 
ATOM   6073  C  CG2 . THR B 1 94  ? 144.119 176.502 150.553 1.00 49.73  ?  83  THR B CG2 1 
ATOM   6074  N  N   . GLY B 1 95  ? 144.633 179.521 153.282 1.00 48.44  ?  84  GLY B N   1 
ATOM   6075  C  CA  . GLY B 1 95  ? 145.085 179.496 154.658 1.00 48.44  ?  84  GLY B CA  1 
ATOM   6076  C  C   . GLY B 1 95  ? 143.956 179.666 155.638 1.00 48.44  ?  84  GLY B C   1 
ATOM   6077  O  O   . GLY B 1 95  ? 143.946 179.023 156.680 1.00 48.44  ?  84  GLY B O   1 
ATOM   6078  N  N   . ILE B 1 96  ? 143.005 180.530 155.317 1.00 49.35  ?  85  ILE B N   1 
ATOM   6079  C  CA  . ILE B 1 96  ? 141.860 180.746 156.180 1.00 49.35  ?  85  ILE B CA  1 
ATOM   6080  C  C   . ILE B 1 96  ? 140.970 179.515 156.209 1.00 49.35  ?  85  ILE B C   1 
ATOM   6081  O  O   . ILE B 1 96  ? 140.514 179.102 157.268 1.00 49.35  ?  85  ILE B O   1 
ATOM   6082  C  CB  . ILE B 1 96  ? 141.057 181.965 155.709 1.00 49.35  ?  85  ILE B CB  1 
ATOM   6083  C  CG1 . ILE B 1 96  ? 141.918 183.226 155.782 1.00 49.35  ?  85  ILE B CG1 1 
ATOM   6084  C  CG2 . ILE B 1 96  ? 139.796 182.126 156.541 1.00 49.35  ?  85  ILE B CG2 1 
ATOM   6085  C  CD1 . ILE B 1 96  ? 141.238 184.459 155.234 1.00 49.35  ?  85  ILE B CD1 1 
ATOM   6086  N  N   . VAL B 1 97  ? 140.732 178.918 155.049 1.00 49.22  ?  86  VAL B N   1 
ATOM   6087  C  CA  . VAL B 1 97  ? 139.925 177.710 154.979 1.00 49.22  ?  86  VAL B CA  1 
ATOM   6088  C  C   . VAL B 1 97  ? 140.637 176.582 155.694 1.00 49.22  ?  86  VAL B C   1 
ATOM   6089  O  O   . VAL B 1 97  ? 139.999 175.738 156.310 1.00 49.22  ?  86  VAL B O   1 
ATOM   6090  C  CB  . VAL B 1 97  ? 139.642 177.308 153.520 1.00 49.22  ?  86  VAL B CB  1 
ATOM   6091  C  CG1 . VAL B 1 97  ? 138.926 175.969 153.454 1.00 49.22  ?  86  VAL B CG1 1 
ATOM   6092  C  CG2 . VAL B 1 97  ? 138.835 178.386 152.819 1.00 49.22  ?  86  VAL B CG2 1 
ATOM   6093  N  N   . ALA B 1 98  ? 141.961 176.568 155.625 1.00 48.01  ?  87  ALA B N   1 
ATOM   6094  C  CA  . ALA B 1 98  ? 142.738 175.515 156.259 1.00 48.01  ?  87  ALA B CA  1 
ATOM   6095  C  C   . ALA B 1 98  ? 142.652 175.580 157.772 1.00 48.01  ?  87  ALA B C   1 
ATOM   6096  O  O   . ALA B 1 98  ? 142.593 174.549 158.432 1.00 48.01  ?  87  ALA B O   1 
ATOM   6097  C  CB  . ALA B 1 98  ? 144.184 175.586 155.807 1.00 48.01  ?  87  ALA B CB  1 
ATOM   6098  N  N   . VAL B 1 99  ? 142.639 176.784 158.328 1.00 46.81  ?  88  VAL B N   1 
ATOM   6099  C  CA  . VAL B 1 99  ? 142.490 176.910 159.776 1.00 46.81  ?  88  VAL B CA  1 
ATOM   6100  C  C   . VAL B 1 99  ? 141.171 176.296 160.236 1.00 46.81  ?  88  VAL B C   1 
ATOM   6101  O  O   . VAL B 1 99  ? 141.133 175.440 161.134 1.00 46.81  ?  88  VAL B O   1 
ATOM   6102  C  CB  . VAL B 1 99  ? 142.602 178.385 160.193 1.00 46.81  ?  88  VAL B CB  1 
ATOM   6103  C  CG1 . VAL B 1 99  ? 142.118 178.574 161.612 1.00 46.81  ?  88  VAL B CG1 1 
ATOM   6104  C  CG2 . VAL B 1 99  ? 144.022 178.860 160.040 1.00 46.81  ?  88  VAL B CG2 1 
ATOM   6105  N  N   . LEU B 1 100 ? 140.069 176.716 159.618 1.00 48.20  ?  89  LEU B N   1 
ATOM   6106  C  CA  . LEU B 1 100 ? 138.755 176.262 160.049 1.00 48.20  ?  89  LEU B CA  1 
ATOM   6107  C  C   . LEU B 1 100 ? 138.555 174.784 159.765 1.00 48.20  ?  89  LEU B C   1 
ATOM   6108  O  O   . LEU B 1 100 ? 138.004 174.053 160.597 1.00 48.20  ?  89  LEU B O   1 
ATOM   6109  C  CB  . LEU B 1 100 ? 137.678 177.093 159.366 1.00 48.20  ?  89  LEU B CB  1 
ATOM   6110  C  CG  . LEU B 1 100 ? 137.674 178.540 159.837 1.00 48.20  ?  89  LEU B CG  1 
ATOM   6111  C  CD1 . LEU B 1 100 ? 136.774 179.381 158.975 1.00 48.20  ?  89  LEU B CD1 1 
ATOM   6112  C  CD2 . LEU B 1 100 ? 137.247 178.606 161.279 1.00 48.20  ?  89  LEU B CD2 1 
ATOM   6113  N  N   . GLN B 1 101 ? 138.994 174.322 158.597 1.00 48.79  ?  90  GLN B N   1 
ATOM   6114  C  CA  . GLN B 1 101 ? 138.877 172.908 158.298 1.00 48.79  ?  90  GLN B CA  1 
ATOM   6115  C  C   . GLN B 1 101 ? 139.741 172.069 159.223 1.00 48.79  ?  90  GLN B C   1 
ATOM   6116  O  O   . GLN B 1 101 ? 139.346 170.964 159.589 1.00 48.79  ?  90  GLN B O   1 
ATOM   6117  C  CB  . GLN B 1 101 ? 139.235 172.657 156.844 1.00 48.79  ?  90  GLN B CB  1 
ATOM   6118  C  CG  . GLN B 1 101 ? 138.146 173.043 155.891 1.00 48.79  ?  90  GLN B CG  1 
ATOM   6119  C  CD  . GLN B 1 101 ? 138.357 172.464 154.533 1.00 48.79  ?  90  GLN B CD  1 
ATOM   6120  O  OE1 . GLN B 1 101 ? 139.408 171.912 154.248 1.00 48.79  ?  90  GLN B OE1 1 
ATOM   6121  N  NE2 . GLN B 1 101 ? 137.364 172.583 153.679 1.00 48.79  ?  90  GLN B NE2 1 
ATOM   6122  N  N   . GLY B 1 102 ? 140.898 172.581 159.644 1.00 46.55  ?  91  GLY B N   1 
ATOM   6123  C  CA  . GLY B 1 102 ? 141.708 171.854 160.599 1.00 46.55  ?  91  GLY B CA  1 
ATOM   6124  C  C   . GLY B 1 102 ? 141.022 171.701 161.937 1.00 46.55  ?  91  GLY B C   1 
ATOM   6125  O  O   . GLY B 1 102 ? 141.015 170.616 162.516 1.00 46.55  ?  91  GLY B O   1 
ATOM   6126  N  N   . LEU B 1 103 ? 140.421 172.781 162.435 1.00 47.21  ?  92  LEU B N   1 
ATOM   6127  C  CA  . LEU B 1 103 ? 139.669 172.689 163.685 1.00 47.21  ?  92  LEU B CA  1 
ATOM   6128  C  C   . LEU B 1 103 ? 138.526 171.679 163.579 1.00 47.21  ?  92  LEU B C   1 
ATOM   6129  O  O   . LEU B 1 103 ? 138.361 170.805 164.444 1.00 47.21  ?  92  LEU B O   1 
ATOM   6130  C  CB  . LEU B 1 103 ? 139.137 174.063 164.075 1.00 47.21  ?  92  LEU B CB  1 
ATOM   6131  C  CG  . LEU B 1 103 ? 140.145 175.178 164.321 1.00 47.21  ?  92  LEU B CG  1 
ATOM   6132  C  CD1 . LEU B 1 103 ? 139.420 176.475 164.548 1.00 47.21  ?  92  LEU B CD1 1 
ATOM   6133  C  CD2 . LEU B 1 103 ? 141.023 174.858 165.492 1.00 47.21  ?  92  LEU B CD2 1 
ATOM   6134  N  N   . ALA B 1 104 ? 137.733 171.773 162.510 1.00 47.04  ?  93  ALA B N   1 
ATOM   6135  C  CA  . ALA B 1 104 ? 136.595 170.873 162.355 1.00 47.04  ?  93  ALA B CA  1 
ATOM   6136  C  C   . ALA B 1 104 ? 137.035 169.418 162.229 1.00 47.04  ?  93  ALA B C   1 
ATOM   6137  O  O   . ALA B 1 104 ? 136.433 168.514 162.823 1.00 47.04  ?  93  ALA B O   1 
ATOM   6138  C  CB  . ALA B 1 104 ? 135.773 171.291 161.141 1.00 47.04  ?  93  ALA B CB  1 
ATOM   6139  N  N   . PHE B 1 105 ? 138.086 169.162 161.467 1.00 45.99  ?  94  PHE B N   1 
ATOM   6140  C  CA  . PHE B 1 105 ? 138.468 167.778 161.256 1.00 45.99  ?  94  PHE B CA  1 
ATOM   6141  C  C   . PHE B 1 105 ? 139.194 167.215 162.468 1.00 45.99  ?  94  PHE B C   1 
ATOM   6142  O  O   . PHE B 1 105 ? 139.175 166.000 162.683 1.00 45.99  ?  94  PHE B O   1 
ATOM   6143  C  CB  . PHE B 1 105 ? 139.302 167.661 159.983 1.00 45.99  ?  94  PHE B CB  1 
ATOM   6144  C  CG  . PHE B 1 105 ? 138.627 168.226 158.760 1.00 45.99  ?  94  PHE B CG  1 
ATOM   6145  C  CD1 . PHE B 1 105 ? 137.262 168.439 158.732 1.00 45.99  ?  94  PHE B CD1 1 
ATOM   6146  C  CD2 . PHE B 1 105 ? 139.360 168.547 157.640 1.00 45.99  ?  94  PHE B CD2 1 
ATOM   6147  C  CE1 . PHE B 1 105 ? 136.654 168.968 157.626 1.00 45.99  ?  94  PHE B CE1 1 
ATOM   6148  C  CE2 . PHE B 1 105 ? 138.752 169.065 156.531 1.00 45.99  ?  94  PHE B CE2 1 
ATOM   6149  C  CZ  . PHE B 1 105 ? 137.400 169.276 156.523 1.00 45.99  ?  94  PHE B CZ  1 
ATOM   6150  N  N   . ALA B 1 106 ? 139.801 168.073 163.289 1.00 47.48  ?  95  ALA B N   1 
ATOM   6151  C  CA  . ALA B 1 106 ? 140.278 167.622 164.588 1.00 47.48  ?  95  ALA B CA  1 
ATOM   6152  C  C   . ALA B 1 106 ? 139.117 167.218 165.477 1.00 47.48  ?  95  ALA B C   1 
ATOM   6153  O  O   . ALA B 1 106 ? 139.233 166.280 166.270 1.00 47.48  ?  95  ALA B O   1 
ATOM   6154  C  CB  . ALA B 1 106 ? 141.108 168.710 165.258 1.00 47.48  ?  95  ALA B CB  1 
ATOM   6155  N  N   . LEU B 1 107 ? 137.990 167.926 165.374 1.00 49.27  ?  96  LEU B N   1 
ATOM   6156  C  CA  . LEU B 1 107 ? 136.774 167.433 166.020 1.00 49.27  ?  96  LEU B CA  1 
ATOM   6157  C  C   . LEU B 1 107 ? 136.424 166.035 165.531 1.00 49.27  ?  96  LEU B C   1 
ATOM   6158  O  O   . LEU B 1 107 ? 136.033 165.173 166.321 1.00 49.27  ?  96  LEU B O   1 
ATOM   6159  C  CB  . LEU B 1 107 ? 135.603 168.373 165.763 1.00 49.27  ?  96  LEU B CB  1 
ATOM   6160  C  CG  . LEU B 1 107 ? 135.566 169.725 166.448 1.00 49.27  ?  96  LEU B CG  1 
ATOM   6161  C  CD1 . LEU B 1 107 ? 134.205 170.325 166.240 1.00 49.27  ?  96  LEU B CD1 1 
ATOM   6162  C  CD2 . LEU B 1 107 ? 135.878 169.574 167.908 1.00 49.27  ?  96  LEU B CD2 1 
ATOM   6163  N  N   . LEU B 1 108 ? 136.546 165.798 164.227 1.00 48.84  ?  97  LEU B N   1 
ATOM   6164  C  CA  . LEU B 1 108 ? 136.246 164.469 163.692 1.00 48.84  ?  97  LEU B CA  1 
ATOM   6165  C  C   . LEU B 1 108 ? 137.199 163.398 164.213 1.00 48.84  ?  97  LEU B C   1 
ATOM   6166  O  O   . LEU B 1 108 ? 136.823 162.226 164.295 1.00 48.84  ?  97  LEU B O   1 
ATOM   6167  C  CB  . LEU B 1 108 ? 136.286 164.486 162.169 1.00 48.84  ?  97  LEU B CB  1 
ATOM   6168  C  CG  . LEU B 1 108 ? 135.046 165.016 161.470 1.00 48.84  ?  97  LEU B CG  1 
ATOM   6169  C  CD1 . LEU B 1 108 ? 135.179 164.810 159.988 1.00 48.84  ?  97  LEU B CD1 1 
ATOM   6170  C  CD2 . LEU B 1 108 ? 133.817 164.324 162.001 1.00 48.84  ?  97  LEU B CD2 1 
ATOM   6171  N  N   . VAL B 1 109 ? 138.447 163.759 164.525 1.00 50.02  ?  98  VAL B N   1 
ATOM   6172  C  CA  . VAL B 1 109 ? 139.381 162.810 165.129 1.00 50.02  ?  98  VAL B CA  1 
ATOM   6173  C  C   . VAL B 1 109 ? 139.145 162.653 166.625 1.00 50.02  ?  98  VAL B C   1 
ATOM   6174  O  O   . VAL B 1 109 ? 139.676 161.716 167.234 1.00 50.02  ?  98  VAL B O   1 
ATOM   6175  C  CB  . VAL B 1 109 ? 140.840 163.235 164.842 1.00 50.02  ?  98  VAL B CB  1 
ATOM   6176  C  CG1 . VAL B 1 109 ? 141.814 162.158 165.241 1.00 50.02  ?  98  VAL B CG1 1 
ATOM   6177  C  CG2 . VAL B 1 109 ? 141.021 163.531 163.389 1.00 50.02  ?  98  VAL B CG2 1 
ATOM   6178  N  N   . ASP B 1 110 ? 138.343 163.529 167.229 1.00 55.06  ?  99  ASP B N   1 
ATOM   6179  C  CA  . ASP B 1 110 ? 138.029 163.498 168.657 1.00 55.06  ?  99  ASP B CA  1 
ATOM   6180  C  C   . ASP B 1 110 ? 139.274 163.774 169.495 1.00 55.06  ?  99  ASP B C   1 
ATOM   6181  O  O   . ASP B 1 110 ? 139.563 163.085 170.471 1.00 55.06  ?  99  ASP B O   1 
ATOM   6182  C  CB  . ASP B 1 110 ? 137.369 162.176 169.054 1.00 55.06  ?  99  ASP B CB  1 
ATOM   6183  C  CG  . ASP B 1 110 ? 136.806 162.198 170.457 1.00 55.06  ?  99  ASP B CG  1 
ATOM   6184  O  OD1 . ASP B 1 110 ? 136.604 163.301 170.998 1.00 55.06  ?  99  ASP B OD1 1 
ATOM   6185  O  OD2 . ASP B 1 110 ? 136.555 161.111 171.017 1.00 55.06  -1 99  ASP B OD2 1 
ATOM   6186  N  N   . ILE B 1 111 ? 140.020 164.796 169.095 1.00 52.91  ?  100 ILE B N   1 
ATOM   6187  C  CA  . ILE B 1 111 ? 141.136 165.325 169.875 1.00 52.91  ?  100 ILE B CA  1 
ATOM   6188  C  C   . ILE B 1 111 ? 140.974 166.827 169.958 1.00 52.91  ?  100 ILE B C   1 
ATOM   6189  O  O   . ILE B 1 111 ? 140.133 167.410 169.252 1.00 52.91  ?  100 ILE B O   1 
ATOM   6190  C  CB  . ILE B 1 111 ? 142.500 164.947 169.252 1.00 52.91  ?  100 ILE B CB  1 
ATOM   6191  C  CG1 . ILE B 1 111 ? 142.612 165.476 167.827 1.00 52.91  ?  100 ILE B CG1 1 
ATOM   6192  C  CG2 . ILE B 1 111 ? 142.701 163.450 169.287 1.00 52.91  ?  100 ILE B CG2 1 
ATOM   6193  C  CD1 . ILE B 1 111 ? 143.862 165.061 167.139 1.00 52.91  ?  100 ILE B CD1 1 
ATOM   6194  N  N   . PRO B 1 112 ? 141.714 167.495 170.840 1.00 54.08  ?  101 PRO B N   1 
ATOM   6195  C  CA  . PRO B 1 112 ? 141.648 168.955 170.914 1.00 54.08  ?  101 PRO B CA  1 
ATOM   6196  C  C   . PRO B 1 112 ? 141.906 169.590 169.559 1.00 54.08  ?  101 PRO B C   1 
ATOM   6197  O  O   . PRO B 1 112 ? 142.726 169.093 168.775 1.00 54.08  ?  101 PRO B O   1 
ATOM   6198  C  CB  . PRO B 1 112 ? 142.753 169.301 171.915 1.00 54.08  ?  101 PRO B CB  1 
ATOM   6199  C  CG  . PRO B 1 112 ? 142.787 168.142 172.803 1.00 54.08  ?  101 PRO B CG  1 
ATOM   6200  C  CD  . PRO B 1 112 ? 142.477 166.938 171.972 1.00 54.08  ?  101 PRO B CD  1 
ATOM   6201  N  N   . PRO B 1 113 ? 141.224 170.695 169.244 1.00 53.22  ?  102 PRO B N   1 
ATOM   6202  C  CA  . PRO B 1 113 ? 141.243 171.218 167.870 1.00 53.22  ?  102 PRO B CA  1 
ATOM   6203  C  C   . PRO B 1 113 ? 142.551 171.849 167.409 1.00 53.22  ?  102 PRO B C   1 
ATOM   6204  O  O   . PRO B 1 113 ? 142.676 172.126 166.212 1.00 53.22  ?  102 PRO B O   1 
ATOM   6205  C  CB  . PRO B 1 113 ? 140.114 172.257 167.884 1.00 53.22  ?  102 PRO B CB  1 
ATOM   6206  C  CG  . PRO B 1 113 ? 139.914 172.595 169.290 1.00 53.22  ?  102 PRO B CG  1 
ATOM   6207  C  CD  . PRO B 1 113 ? 140.205 171.361 170.066 1.00 53.22  ?  102 PRO B CD  1 
ATOM   6208  N  N   . VAL B 1 114 ? 143.529 172.082 168.285 1.00 51.63  ?  103 VAL B N   1 
ATOM   6209  C  CA  . VAL B 1 114 ? 144.792 172.661 167.834 1.00 51.63  ?  103 VAL B CA  1 
ATOM   6210  C  C   . VAL B 1 114 ? 145.628 171.660 167.042 1.00 51.63  ?  103 VAL B C   1 
ATOM   6211  O  O   . VAL B 1 114 ? 146.447 172.054 166.195 1.00 51.63  ?  103 VAL B O   1 
ATOM   6212  C  CB  . VAL B 1 114 ? 145.572 173.213 169.040 1.00 51.63  ?  103 VAL B CB  1 
ATOM   6213  C  CG1 . VAL B 1 114 ? 146.055 172.092 169.928 1.00 51.63  ?  103 VAL B CG1 1 
ATOM   6214  C  CG2 . VAL B 1 114 ? 146.726 174.078 168.587 1.00 51.63  ?  103 VAL B CG2 1 
ATOM   6215  N  N   . TYR B 1 115 ? 145.427 170.369 167.270 1.00 50.69  ?  104 TYR B N   1 
ATOM   6216  C  CA  . TYR B 1 115 ? 146.147 169.372 166.504 1.00 50.69  ?  104 TYR B CA  1 
ATOM   6217  C  C   . TYR B 1 115 ? 145.699 169.348 165.054 1.00 50.69  ?  104 TYR B C   1 
ATOM   6218  O  O   . TYR B 1 115 ? 146.477 168.955 164.182 1.00 50.69  ?  104 TYR B O   1 
ATOM   6219  C  CB  . TYR B 1 115 ? 145.987 168.019 167.185 1.00 50.69  ?  104 TYR B CB  1 
ATOM   6220  C  CG  . TYR B 1 115 ? 146.472 168.063 168.613 1.00 50.69  ?  104 TYR B CG  1 
ATOM   6221  C  CD1 . TYR B 1 115 ? 147.814 167.929 168.911 1.00 50.69  ?  104 TYR B CD1 1 
ATOM   6222  C  CD2 . TYR B 1 115 ? 145.598 168.282 169.657 1.00 50.69  ?  104 TYR B CD2 1 
ATOM   6223  C  CE1 . TYR B 1 115 ? 148.265 167.988 170.196 1.00 50.69  ?  104 TYR B CE1 1 
ATOM   6224  C  CE2 . TYR B 1 115 ? 146.043 168.345 170.949 1.00 50.69  ?  104 TYR B CE2 1 
ATOM   6225  C  CZ  . TYR B 1 115 ? 147.378 168.197 171.211 1.00 50.69  ?  104 TYR B CZ  1 
ATOM   6226  O  OH  . TYR B 1 115 ? 147.832 168.256 172.502 1.00 50.69  ?  104 TYR B OH  1 
ATOM   6227  N  N   . GLY B 1 116 ? 144.486 169.816 164.769 1.00 48.08  ?  105 GLY B N   1 
ATOM   6228  C  CA  . GLY B 1 116 ? 144.098 170.043 163.392 1.00 48.08  ?  105 GLY B CA  1 
ATOM   6229  C  C   . GLY B 1 116 ? 144.876 171.167 162.751 1.00 48.08  ?  105 GLY B C   1 
ATOM   6230  O  O   . GLY B 1 116 ? 145.163 171.126 161.555 1.00 48.08  ?  105 GLY B O   1 
ATOM   6231  N  N   . LEU B 1 117 ? 145.248 172.175 163.535 1.00 47.72  ?  106 LEU B N   1 
ATOM   6232  C  CA  . LEU B 1 117 ? 146.129 173.216 163.028 1.00 47.72  ?  106 LEU B CA  1 
ATOM   6233  C  C   . LEU B 1 117 ? 147.510 172.661 162.721 1.00 47.72  ?  106 LEU B C   1 
ATOM   6234  O  O   . LEU B 1 117 ? 148.119 173.018 161.707 1.00 47.72  ?  106 LEU B O   1 
ATOM   6235  C  CB  . LEU B 1 117 ? 146.215 174.355 164.034 1.00 47.72  ?  106 LEU B CB  1 
ATOM   6236  C  CG  . LEU B 1 117 ? 144.917 175.095 164.329 1.00 47.72  ?  106 LEU B CG  1 
ATOM   6237  C  CD1 . LEU B 1 117 ? 145.163 176.198 165.324 1.00 47.72  ?  106 LEU B CD1 1 
ATOM   6238  C  CD2 . LEU B 1 117 ? 144.331 175.651 163.058 1.00 47.72  ?  106 LEU B CD2 1 
ATOM   6239  N  N   . TYR B 1 118 ? 148.022 171.781 163.582 1.00 49.06  ?  107 TYR B N   1 
ATOM   6240  C  CA  . TYR B 1 118 ? 149.288 171.118 163.271 1.00 49.06  ?  107 TYR B CA  1 
ATOM   6241  C  C   . TYR B 1 118 ? 149.188 170.313 161.982 1.00 49.06  ?  107 TYR B C   1 
ATOM   6242  O  O   . TYR B 1 118 ? 150.132 170.278 161.177 1.00 49.06  ?  107 TYR B O   1 
ATOM   6243  C  CB  . TYR B 1 118 ? 149.703 170.206 164.419 1.00 49.06  ?  107 TYR B CB  1 
ATOM   6244  C  CG  . TYR B 1 118 ? 149.856 170.896 165.740 1.00 49.06  ?  107 TYR B CG  1 
ATOM   6245  C  CD1 . TYR B 1 118 ? 150.167 172.237 165.810 1.00 49.06  ?  107 TYR B CD1 1 
ATOM   6246  C  CD2 . TYR B 1 118 ? 149.693 170.202 166.921 1.00 49.06  ?  107 TYR B CD2 1 
ATOM   6247  C  CE1 . TYR B 1 118 ? 150.305 172.864 167.012 1.00 49.06  ?  107 TYR B CE1 1 
ATOM   6248  C  CE2 . TYR B 1 118 ? 149.831 170.822 168.125 1.00 49.06  ?  107 TYR B CE2 1 
ATOM   6249  C  CZ  . TYR B 1 118 ? 150.140 172.151 168.167 1.00 49.06  ?  107 TYR B CZ  1 
ATOM   6250  O  OH  . TYR B 1 118 ? 150.280 172.780 169.373 1.00 49.06  ?  107 TYR B OH  1 
ATOM   6251  N  N   . ALA B 1 119 ? 148.057 169.635 161.788 1.00 46.72  ?  108 ALA B N   1 
ATOM   6252  C  CA  . ALA B 1 119 ? 147.844 168.837 160.590 1.00 46.72  ?  108 ALA B CA  1 
ATOM   6253  C  C   . ALA B 1 119 ? 147.712 169.702 159.347 1.00 46.72  ?  108 ALA B C   1 
ATOM   6254  O  O   . ALA B 1 119 ? 148.027 169.248 158.245 1.00 46.72  ?  108 ALA B O   1 
ATOM   6255  C  CB  . ALA B 1 119 ? 146.608 167.963 160.762 1.00 46.72  ?  108 ALA B CB  1 
ATOM   6256  N  N   . SER B 1 120 ? 147.230 170.930 159.492 1.00 47.48  ?  109 SER B N   1 
ATOM   6257  C  CA  . SER B 1 120 ? 147.210 171.858 158.370 1.00 47.48  ?  109 SER B CA  1 
ATOM   6258  C  C   . SER B 1 120 ? 148.556 172.518 158.122 1.00 47.48  ?  109 SER B C   1 
ATOM   6259  O  O   . SER B 1 120 ? 148.768 173.063 157.037 1.00 47.48  ?  109 SER B O   1 
ATOM   6260  C  CB  . SER B 1 120 ? 146.166 172.945 158.591 1.00 47.48  ?  109 SER B CB  1 
ATOM   6261  O  OG  . SER B 1 120 ? 144.997 172.411 159.160 1.00 47.48  ?  109 SER B OG  1 
ATOM   6262  N  N   . PHE B 1 121 ? 149.453 172.508 159.101 1.00 47.02  ?  110 PHE B N   1 
ATOM   6263  C  CA  . PHE B 1 121 ? 150.734 173.176 158.914 1.00 47.02  ?  110 PHE B CA  1 
ATOM   6264  C  C   . PHE B 1 121 ? 151.813 172.265 158.339 1.00 47.02  ?  110 PHE B C   1 
ATOM   6265  O  O   . PHE B 1 121 ? 152.405 172.586 157.308 1.00 47.02  ?  110 PHE B O   1 
ATOM   6266  C  CB  . PHE B 1 121 ? 151.217 173.766 160.237 1.00 47.02  ?  110 PHE B CB  1 
ATOM   6267  C  CG  . PHE B 1 121 ? 152.521 174.482 160.132 1.00 47.02  ?  110 PHE B CG  1 
ATOM   6268  C  CD1 . PHE B 1 121 ? 152.606 175.691 159.482 1.00 47.02  ?  110 PHE B CD1 1 
ATOM   6269  C  CD2 . PHE B 1 121 ? 153.662 173.948 160.681 1.00 47.02  ?  110 PHE B CD2 1 
ATOM   6270  C  CE1 . PHE B 1 121 ? 153.799 176.349 159.382 1.00 47.02  ?  110 PHE B CE1 1 
ATOM   6271  C  CE2 . PHE B 1 121 ? 154.857 174.605 160.583 1.00 47.02  ?  110 PHE B CE2 1 
ATOM   6272  C  CZ  . PHE B 1 121 ? 154.923 175.807 159.933 1.00 47.02  ?  110 PHE B CZ  1 
ATOM   6273  N  N   . PHE B 1 122 ? 152.093 171.133 158.989 1.00 47.09  ?  111 PHE B N   1 
ATOM   6274  C  CA  . PHE B 1 122 ? 153.340 170.427 158.687 1.00 47.09  ?  111 PHE B CA  1 
ATOM   6275  C  C   . PHE B 1 122 ? 153.352 169.760 157.312 1.00 47.09  ?  111 PHE B C   1 
ATOM   6276  O  O   . PHE B 1 122 ? 154.343 169.928 156.574 1.00 47.09  ?  111 PHE B O   1 
ATOM   6277  C  CB  . PHE B 1 122 ? 153.658 169.430 159.803 1.00 47.09  ?  111 PHE B CB  1 
ATOM   6278  C  CG  . PHE B 1 122 ? 154.168 170.074 161.050 1.00 47.09  ?  111 PHE B CG  1 
ATOM   6279  C  CD1 . PHE B 1 122 ? 155.435 170.607 161.097 1.00 47.09  ?  111 PHE B CD1 1 
ATOM   6280  C  CD2 . PHE B 1 122 ? 153.374 170.162 162.172 1.00 47.09  ?  111 PHE B CD2 1 
ATOM   6281  C  CE1 . PHE B 1 122 ? 155.898 171.206 162.235 1.00 47.09  ?  111 PHE B CE1 1 
ATOM   6282  C  CE2 . PHE B 1 122 ? 153.836 170.764 163.308 1.00 47.09  ?  111 PHE B CE2 1 
ATOM   6283  C  CZ  . PHE B 1 122 ? 155.100 171.284 163.339 1.00 47.09  ?  111 PHE B CZ  1 
ATOM   6284  N  N   . PRO B 1 123 ? 152.335 168.992 156.912 1.00 46.78  ?  112 PRO B N   1 
ATOM   6285  C  CA  . PRO B 1 123 ? 152.405 168.350 155.594 1.00 46.78  ?  112 PRO B CA  1 
ATOM   6286  C  C   . PRO B 1 123 ? 152.494 169.331 154.444 1.00 46.78  ?  112 PRO B C   1 
ATOM   6287  O  O   . PRO B 1 123 ? 153.132 169.019 153.438 1.00 46.78  ?  112 PRO B O   1 
ATOM   6288  C  CB  . PRO B 1 123 ? 151.113 167.527 155.541 1.00 46.78  ?  112 PRO B CB  1 
ATOM   6289  C  CG  . PRO B 1 123 ? 150.727 167.344 156.936 1.00 46.78  ?  112 PRO B CG  1 
ATOM   6290  C  CD  . PRO B 1 123 ? 151.118 168.587 157.631 1.00 46.78  ?  112 PRO B CD  1 
ATOM   6291  N  N   . ALA B 1 124 ? 151.887 170.511 154.559 1.00 47.02  ?  113 ALA B N   1 
ATOM   6292  C  CA  . ALA B 1 124 ? 151.995 171.504 153.498 1.00 47.02  ?  113 ALA B CA  1 
ATOM   6293  C  C   . ALA B 1 124 ? 153.424 172.008 153.351 1.00 47.02  ?  113 ALA B C   1 
ATOM   6294  O  O   . ALA B 1 124 ? 153.916 172.191 152.232 1.00 47.02  ?  113 ALA B O   1 
ATOM   6295  C  CB  . ALA B 1 124 ? 151.045 172.666 153.773 1.00 47.02  ?  113 ALA B CB  1 
ATOM   6296  N  N   . ILE B 1 125 ? 154.109 172.233 154.470 1.00 48.31  ?  114 ILE B N   1 
ATOM   6297  C  CA  . ILE B 1 125 ? 155.487 172.695 154.408 1.00 48.31  ?  114 ILE B CA  1 
ATOM   6298  C  C   . ILE B 1 125 ? 156.381 171.629 153.796 1.00 48.31  ?  114 ILE B C   1 
ATOM   6299  O  O   . ILE B 1 125 ? 157.306 171.943 153.042 1.00 48.31  ?  114 ILE B O   1 
ATOM   6300  C  CB  . ILE B 1 125 ? 155.981 173.114 155.802 1.00 48.31  ?  114 ILE B CB  1 
ATOM   6301  C  CG1 . ILE B 1 125 ? 155.205 174.324 156.295 1.00 48.31  ?  114 ILE B CG1 1 
ATOM   6302  C  CG2 . ILE B 1 125 ? 157.448 173.460 155.760 1.00 48.31  ?  114 ILE B CG2 1 
ATOM   6303  C  CD1 . ILE B 1 125 ? 155.443 175.549 155.483 1.00 48.31  ?  114 ILE B CD1 1 
ATOM   6304  N  N   . ILE B 1 126 ? 156.132 170.355 154.099 1.00 46.46  ?  115 ILE B N   1 
ATOM   6305  C  CA  . ILE B 1 126 ? 156.977 169.326 153.496 1.00 46.46  ?  115 ILE B CA  1 
ATOM   6306  C  C   . ILE B 1 126 ? 156.659 169.172 152.010 1.00 46.46  ?  115 ILE B C   1 
ATOM   6307  O  O   . ILE B 1 126 ? 157.561 169.010 151.174 1.00 46.46  ?  115 ILE B O   1 
ATOM   6308  C  CB  . ILE B 1 126 ? 156.840 167.996 154.258 1.00 46.46  ?  115 ILE B CB  1 
ATOM   6309  C  CG1 . ILE B 1 126 ? 157.187 168.179 155.731 1.00 46.46  ?  115 ILE B CG1 1 
ATOM   6310  C  CG2 . ILE B 1 126 ? 157.788 166.968 153.705 1.00 46.46  ?  115 ILE B CG2 1 
ATOM   6311  C  CD1 . ILE B 1 126 ? 158.562 168.682 155.991 1.00 46.46  ?  115 ILE B CD1 1 
ATOM   6312  N  N   . TYR B 1 127 ? 155.378 169.245 151.653 1.00 46.18  ?  116 TYR B N   1 
ATOM   6313  C  CA  . TYR B 1 127 ? 154.973 169.092 150.264 1.00 46.18  ?  116 TYR B CA  1 
ATOM   6314  C  C   . TYR B 1 127 ? 155.485 170.228 149.399 1.00 46.18  ?  116 TYR B C   1 
ATOM   6315  O  O   . TYR B 1 127 ? 155.691 170.040 148.198 1.00 46.18  ?  116 TYR B O   1 
ATOM   6316  C  CB  . TYR B 1 127 ? 153.454 169.009 150.176 1.00 46.18  ?  116 TYR B CB  1 
ATOM   6317  C  CG  . TYR B 1 127 ? 152.957 168.460 148.873 1.00 46.18  ?  116 TYR B CG  1 
ATOM   6318  C  CD1 . TYR B 1 127 ? 152.769 167.108 148.705 1.00 46.18  ?  116 TYR B CD1 1 
ATOM   6319  C  CD2 . TYR B 1 127 ? 152.681 169.297 147.809 1.00 46.18  ?  116 TYR B CD2 1 
ATOM   6320  C  CE1 . TYR B 1 127 ? 152.325 166.606 147.526 1.00 46.18  ?  116 TYR B CE1 1 
ATOM   6321  C  CE2 . TYR B 1 127 ? 152.239 168.803 146.625 1.00 46.18  ?  116 TYR B CE2 1 
ATOM   6322  C  CZ  . TYR B 1 127 ? 152.060 167.458 146.489 1.00 46.18  ?  116 TYR B CZ  1 
ATOM   6323  O  OH  . TYR B 1 127 ? 151.613 166.953 145.305 1.00 46.18  ?  116 TYR B OH  1 
ATOM   6324  N  N   . LEU B 1 128 ? 155.673 171.412 149.978 1.00 49.51  ?  117 LEU B N   1 
ATOM   6325  C  CA  . LEU B 1 128 ? 156.284 172.505 149.235 1.00 49.51  ?  117 LEU B CA  1 
ATOM   6326  C  C   . LEU B 1 128 ? 157.617 172.097 148.630 1.00 49.51  ?  117 LEU B C   1 
ATOM   6327  O  O   . LEU B 1 128 ? 157.941 172.499 147.511 1.00 49.51  ?  117 LEU B O   1 
ATOM   6328  C  CB  . LEU B 1 128 ? 156.466 173.711 150.149 1.00 49.51  ?  117 LEU B CB  1 
ATOM   6329  C  CG  . LEU B 1 128 ? 157.406 174.805 149.663 1.00 49.51  ?  117 LEU B CG  1 
ATOM   6330  C  CD1 . LEU B 1 128 ? 156.704 175.707 148.683 1.00 49.51  ?  117 LEU B CD1 1 
ATOM   6331  C  CD2 . LEU B 1 128 ? 157.925 175.591 150.835 1.00 49.51  ?  117 LEU B CD2 1 
ATOM   6332  N  N   . PHE B 1 129 ? 158.388 171.281 149.338 1.00 52.03  ?  118 PHE B N   1 
ATOM   6333  C  CA  . PHE B 1 129 ? 159.696 170.853 148.869 1.00 52.03  ?  118 PHE B CA  1 
ATOM   6334  C  C   . PHE B 1 129 ? 159.642 169.577 148.048 1.00 52.03  ?  118 PHE B C   1 
ATOM   6335  O  O   . PHE B 1 129 ? 160.376 169.447 147.067 1.00 52.03  ?  118 PHE B O   1 
ATOM   6336  C  CB  . PHE B 1 129 ? 160.637 170.640 150.050 1.00 52.03  ?  118 PHE B CB  1 
ATOM   6337  C  CG  . PHE B 1 129 ? 160.966 171.887 150.785 1.00 52.03  ?  118 PHE B CG  1 
ATOM   6338  C  CD1 . PHE B 1 129 ? 161.871 172.783 150.270 1.00 52.03  ?  118 PHE B CD1 1 
ATOM   6339  C  CD2 . PHE B 1 129 ? 160.376 172.164 151.997 1.00 52.03  ?  118 PHE B CD2 1 
ATOM   6340  C  CE1 . PHE B 1 129 ? 162.177 173.928 150.944 1.00 52.03  ?  118 PHE B CE1 1 
ATOM   6341  C  CE2 . PHE B 1 129 ? 160.681 173.308 152.674 1.00 52.03  ?  118 PHE B CE2 1 
ATOM   6342  C  CZ  . PHE B 1 129 ? 161.581 174.193 152.147 1.00 52.03  ?  118 PHE B CZ  1 
ATOM   6343  N  N   . PHE B 1 130 ? 158.782 168.623 148.358 1.00 51.60  ?  119 PHE B N   1 
ATOM   6344  C  CA  . PHE B 1 130 ? 158.814 167.375 147.598 1.00 51.60  ?  119 PHE B CA  1 
ATOM   6345  C  C   . PHE B 1 130 ? 157.702 167.060 146.616 1.00 51.60  ?  119 PHE B C   1 
ATOM   6346  O  O   . PHE B 1 130 ? 157.807 166.104 145.888 1.00 51.60  ?  119 PHE B O   1 
ATOM   6347  C  CB  . PHE B 1 130 ? 158.958 166.193 148.561 1.00 51.60  ?  119 PHE B CB  1 
ATOM   6348  C  CG  . PHE B 1 130 ? 160.168 166.271 149.436 1.00 51.60  ?  119 PHE B CG  1 
ATOM   6349  C  CD1 . PHE B 1 130 ? 161.370 165.751 149.016 1.00 51.60  ?  119 PHE B CD1 1 
ATOM   6350  C  CD2 . PHE B 1 130 ? 160.106 166.876 150.672 1.00 51.60  ?  119 PHE B CD2 1 
ATOM   6351  C  CE1 . PHE B 1 130 ? 162.484 165.824 149.816 1.00 51.60  ?  119 PHE B CE1 1 
ATOM   6352  C  CE2 . PHE B 1 130 ? 161.217 166.957 151.474 1.00 51.60  ?  119 PHE B CE2 1 
ATOM   6353  C  CZ  . PHE B 1 130 ? 162.409 166.430 151.046 1.00 51.60  ?  119 PHE B CZ  1 
ATOM   6354  N  N   . GLY B 1 131 ? 156.622 167.818 146.627 1.00 49.65  ?  120 GLY B N   1 
ATOM   6355  C  CA  . GLY B 1 131 ? 155.508 167.549 145.744 1.00 49.65  ?  120 GLY B CA  1 
ATOM   6356  C  C   . GLY B 1 131 ? 155.648 167.923 144.294 1.00 49.65  ?  120 GLY B C   1 
ATOM   6357  O  O   . GLY B 1 131 ? 156.384 168.832 143.966 1.00 49.65  ?  120 GLY B O   1 
ATOM   6358  N  N   . THR B 1 132 ? 154.960 167.208 143.416 1.00 51.94  ?  121 THR B N   1 
ATOM   6359  C  CA  . THR B 1 132 ? 154.994 167.540 141.997 1.00 51.94  ?  121 THR B CA  1 
ATOM   6360  C  C   . THR B 1 132 ? 153.747 168.281 141.531 1.00 51.94  ?  121 THR B C   1 
ATOM   6361  O  O   . THR B 1 132 ? 153.737 168.847 140.456 1.00 51.94  ?  121 THR B O   1 
ATOM   6362  C  CB  . THR B 1 132 ? 155.275 166.322 141.089 1.00 51.94  ?  121 THR B CB  1 
ATOM   6363  O  OG1 . THR B 1 132 ? 154.132 165.470 141.032 1.00 51.94  ?  121 THR B OG1 1 
ATOM   6364  C  CG2 . THR B 1 132 ? 156.457 165.550 141.597 1.00 51.94  ?  121 THR B CG2 1 
ATOM   6365  N  N   . SER B 1 133 ? 152.695 168.254 142.334 1.00 48.75  ?  122 SER B N   1 
ATOM   6366  C  CA  . SER B 1 133 ? 151.468 168.954 142.009 1.00 48.75  ?  122 SER B CA  1 
ATOM   6367  C  C   . SER B 1 133 ? 151.622 170.418 142.333 1.00 48.75  ?  122 SER B C   1 
ATOM   6368  O  O   . SER B 1 133 ? 152.354 170.776 143.231 1.00 48.75  ?  122 SER B O   1 
ATOM   6369  C  CB  . SER B 1 133 ? 150.292 168.372 142.770 1.00 48.75  ?  122 SER B CB  1 
ATOM   6370  O  OG  . SER B 1 133 ? 149.146 169.166 142.603 1.00 48.75  ?  122 SER B OG  1 
ATOM   6371  N  N   . ARG B 1 134 ? 150.914 171.269 141.616 1.00 49.98  ?  123 ARG B N   1 
ATOM   6372  C  CA  . ARG B 1 134 ? 151.016 172.695 141.852 1.00 49.98  ?  123 ARG B CA  1 
ATOM   6373  C  C   . ARG B 1 134 ? 149.730 173.331 142.314 1.00 49.98  ?  123 ARG B C   1 
ATOM   6374  O  O   . ARG B 1 134 ? 149.672 174.524 142.456 1.00 49.98  ?  123 ARG B O   1 
ATOM   6375  C  CB  . ARG B 1 134 ? 151.400 173.370 140.545 1.00 49.98  ?  123 ARG B CB  1 
ATOM   6376  C  CG  . ARG B 1 134 ? 152.701 172.883 139.957 1.00 49.98  ?  123 ARG B CG  1 
ATOM   6377  C  CD  . ARG B 1 134 ? 152.804 173.233 138.498 1.00 49.98  ?  123 ARG B CD  1 
ATOM   6378  N  NE  . ARG B 1 134 ? 152.026 174.417 138.197 1.00 49.98  ?  123 ARG B NE  1 
ATOM   6379  C  CZ  . ARG B 1 134 ? 151.893 174.927 136.979 1.00 49.98  ?  123 ARG B CZ  1 
ATOM   6380  N  NH1 . ARG B 1 134 ? 151.165 176.015 136.789 1.00 49.98  1  123 ARG B NH1 1 
ATOM   6381  N  NH2 . ARG B 1 134 ? 152.492 174.348 135.951 1.00 49.98  ?  123 ARG B NH2 1 
ATOM   6382  N  N   . HIS B 1 135 ? 148.693 172.547 142.578 1.00 48.90  ?  124 HIS B N   1 
ATOM   6383  C  CA  . HIS B 1 135 ? 147.386 173.117 142.832 1.00 48.90  ?  124 HIS B CA  1 
ATOM   6384  C  C   . HIS B 1 135 ? 146.640 172.533 144.019 1.00 48.90  ?  124 HIS B C   1 
ATOM   6385  O  O   . HIS B 1 135 ? 145.639 173.122 144.428 1.00 48.90  ?  124 HIS B O   1 
ATOM   6386  C  CB  . HIS B 1 135 ? 146.511 172.988 141.578 1.00 48.90  ?  124 HIS B CB  1 
ATOM   6387  C  CG  . HIS B 1 135 ? 146.973 173.842 140.444 1.00 48.90  ?  124 HIS B CG  1 
ATOM   6388  N  ND1 . HIS B 1 135 ? 147.765 173.362 139.428 1.00 48.90  ?  124 HIS B ND1 1 
ATOM   6389  C  CD2 . HIS B 1 135 ? 146.784 175.154 140.186 1.00 48.90  ?  124 HIS B CD2 1 
ATOM   6390  C  CE1 . HIS B 1 135 ? 148.038 174.340 138.588 1.00 48.90  ?  124 HIS B CE1 1 
ATOM   6391  N  NE2 . HIS B 1 135 ? 147.452 175.438 139.024 1.00 48.90  ?  124 HIS B NE2 1 
ATOM   6392  N  N   . ILE B 1 136 ? 147.070 171.426 144.584 1.00 46.10  ?  125 ILE B N   1 
ATOM   6393  C  CA  . ILE B 1 136 ? 146.345 170.842 145.704 1.00 46.10  ?  125 ILE B CA  1 
ATOM   6394  C  C   . ILE B 1 136 ? 146.781 171.516 146.991 1.00 46.10  ?  125 ILE B C   1 
ATOM   6395  O  O   . ILE B 1 136 ? 147.935 171.922 147.146 1.00 46.10  ?  125 ILE B O   1 
ATOM   6396  C  CB  . ILE B 1 136 ? 146.539 169.316 145.780 1.00 46.10  ?  125 ILE B CB  1 
ATOM   6397  C  CG1 . ILE B 1 136 ? 147.999 168.953 146.025 1.00 46.10  ?  125 ILE B CG1 1 
ATOM   6398  C  CG2 . ILE B 1 136 ? 145.985 168.652 144.541 1.00 46.10  ?  125 ILE B CG2 1 
ATOM   6399  C  CD1 . ILE B 1 136 ? 148.187 167.550 146.510 1.00 46.10  ?  125 ILE B CD1 1 
ATOM   6400  N  N   . SER B 1 137 ? 145.839 171.661 147.908 1.00 46.58  ?  126 SER B N   1 
ATOM   6401  C  CA  . SER B 1 137 ? 146.105 172.183 149.236 1.00 46.58  ?  126 SER B CA  1 
ATOM   6402  C  C   . SER B 1 137 ? 146.246 171.002 150.182 1.00 46.58  ?  126 SER B C   1 
ATOM   6403  O  O   . SER B 1 137 ? 145.276 170.283 150.426 1.00 46.58  ?  126 SER B O   1 
ATOM   6404  C  CB  . SER B 1 137 ? 144.986 173.116 149.681 1.00 46.58  ?  126 SER B CB  1 
ATOM   6405  O  OG  . SER B 1 137 ? 145.050 173.340 151.069 1.00 46.58  ?  126 SER B OG  1 
ATOM   6406  N  N   . VAL B 1 138 ? 147.445 170.799 150.698 1.00 45.63  ?  127 VAL B N   1 
ATOM   6407  C  CA  . VAL B 1 138 ? 147.770 169.607 151.468 1.00 45.63  ?  127 VAL B CA  1 
ATOM   6408  C  C   . VAL B 1 138 ? 147.383 169.819 152.922 1.00 45.63  ?  127 VAL B C   1 
ATOM   6409  O  O   . VAL B 1 138 ? 147.686 170.856 153.518 1.00 45.63  ?  127 VAL B O   1 
ATOM   6410  C  CB  . VAL B 1 138 ? 149.261 169.259 151.326 1.00 45.63  ?  127 VAL B CB  1 
ATOM   6411  C  CG1 . VAL B 1 138 ? 149.614 168.074 152.183 1.00 45.63  ?  127 VAL B CG1 1 
ATOM   6412  C  CG2 . VAL B 1 138 ? 149.571 168.958 149.888 1.00 45.63  ?  127 VAL B CG2 1 
ATOM   6413  N  N   . GLY B 1 139 ? 146.703 168.833 153.491 1.00 45.49  ?  128 GLY B N   1 
ATOM   6414  C  CA  . GLY B 1 139 ? 146.202 168.914 154.837 1.00 45.49  ?  128 GLY B CA  1 
ATOM   6415  C  C   . GLY B 1 139 ? 145.121 167.886 155.066 1.00 45.49  ?  128 GLY B C   1 
ATOM   6416  O  O   . GLY B 1 139 ? 144.939 166.964 154.273 1.00 45.49  ?  128 GLY B O   1 
ATOM   6417  N  N   . PRO B 1 140 ? 144.371 168.029 156.149 1.00 45.06  ?  129 PRO B N   1 
ATOM   6418  C  CA  . PRO B 1 140 ? 143.351 167.035 156.487 1.00 45.06  ?  129 PRO B CA  1 
ATOM   6419  C  C   . PRO B 1 140 ? 142.077 167.189 155.664 1.00 45.06  ?  129 PRO B C   1 
ATOM   6420  O  O   . PRO B 1 140 ? 141.772 168.249 155.122 1.00 45.06  ?  129 PRO B O   1 
ATOM   6421  C  CB  . PRO B 1 140 ? 143.084 167.317 157.970 1.00 45.06  ?  129 PRO B CB  1 
ATOM   6422  C  CG  . PRO B 1 140 ? 143.422 168.738 158.148 1.00 45.06  ?  129 PRO B CG  1 
ATOM   6423  C  CD  . PRO B 1 140 ? 144.476 169.092 157.159 1.00 45.06  ?  129 PRO B CD  1 
ATOM   6424  N  N   . PHE B 1 141 ? 141.342 166.091 155.565 1.00 44.09  ?  130 PHE B N   1 
ATOM   6425  C  CA  . PHE B 1 141 ? 140.018 166.084 154.965 1.00 44.09  ?  130 PHE B CA  1 
ATOM   6426  C  C   . PHE B 1 141 ? 139.135 165.139 155.758 1.00 44.09  ?  130 PHE B C   1 
ATOM   6427  O  O   . PHE B 1 141 ? 139.638 164.313 156.528 1.00 44.09  ?  130 PHE B O   1 
ATOM   6428  C  CB  . PHE B 1 141 ? 140.068 165.723 153.470 1.00 44.09  ?  130 PHE B CB  1 
ATOM   6429  C  CG  . PHE B 1 141 ? 140.603 164.360 153.158 1.00 44.09  ?  130 PHE B CG  1 
ATOM   6430  C  CD1 . PHE B 1 141 ? 139.752 163.358 152.741 1.00 44.09  ?  130 PHE B CD1 1 
ATOM   6431  C  CD2 . PHE B 1 141 ? 141.955 164.098 153.203 1.00 44.09  ?  130 PHE B CD2 1 
ATOM   6432  C  CE1 . PHE B 1 141 ? 140.227 162.115 152.423 1.00 44.09  ?  130 PHE B CE1 1 
ATOM   6433  C  CE2 . PHE B 1 141 ? 142.436 162.853 152.881 1.00 44.09  ?  130 PHE B CE2 1 
ATOM   6434  C  CZ  . PHE B 1 141 ? 141.570 161.860 152.490 1.00 44.09  ?  130 PHE B CZ  1 
ATOM   6435  N  N   . PRO B 1 142 ? 137.804 165.256 155.632 1.00 46.34  ?  131 PRO B N   1 
ATOM   6436  C  CA  . PRO B 1 142 ? 136.914 164.582 156.595 1.00 46.34  ?  131 PRO B CA  1 
ATOM   6437  C  C   . PRO B 1 142 ? 136.992 163.066 156.608 1.00 46.34  ?  131 PRO B C   1 
ATOM   6438  O  O   . PRO B 1 142 ? 136.947 162.465 157.686 1.00 46.34  ?  131 PRO B O   1 
ATOM   6439  C  CB  . PRO B 1 142 ? 135.525 165.057 156.160 1.00 46.34  ?  131 PRO B CB  1 
ATOM   6440  C  CG  . PRO B 1 142 ? 135.757 166.290 155.445 1.00 46.34  ?  131 PRO B CG  1 
ATOM   6441  C  CD  . PRO B 1 142 ? 137.042 166.142 154.739 1.00 46.34  ?  131 PRO B CD  1 
ATOM   6442  N  N   . ILE B 1 143 ? 137.080 162.426 155.445 1.00 46.74  ?  132 ILE B N   1 
ATOM   6443  C  CA  . ILE B 1 143 ? 137.095 160.968 155.411 1.00 46.74  ?  132 ILE B CA  1 
ATOM   6444  C  C   . ILE B 1 143 ? 138.321 160.432 156.132 1.00 46.74  ?  132 ILE B C   1 
ATOM   6445  O  O   . ILE B 1 143 ? 138.234 159.482 156.920 1.00 46.74  ?  132 ILE B O   1 
ATOM   6446  C  CB  . ILE B 1 143 ? 137.024 160.467 153.960 1.00 46.74  ?  132 ILE B CB  1 
ATOM   6447  C  CG1 . ILE B 1 143 ? 135.654 160.771 153.368 1.00 46.74  ?  132 ILE B CG1 1 
ATOM   6448  C  CG2 . ILE B 1 143 ? 137.306 158.985 153.890 1.00 46.74  ?  132 ILE B CG2 1 
ATOM   6449  C  CD1 . ILE B 1 143 ? 135.582 160.547 151.884 1.00 46.74  ?  132 ILE B CD1 1 
ATOM   6450  N  N   . LEU B 1 144 ? 139.479 161.046 155.899 1.00 44.86  ?  133 LEU B N   1 
ATOM   6451  C  CA  . LEU B 1 144 ? 140.686 160.579 156.558 1.00 44.86  ?  133 LEU B CA  1 
ATOM   6452  C  C   . LEU B 1 144 ? 140.671 160.876 158.045 1.00 44.86  ?  133 LEU B C   1 
ATOM   6453  O  O   . LEU B 1 144 ? 141.209 160.096 158.826 1.00 44.86  ?  133 LEU B O   1 
ATOM   6454  C  CB  . LEU B 1 144 ? 141.918 161.194 155.915 1.00 44.86  ?  133 LEU B CB  1 
ATOM   6455  C  CG  . LEU B 1 144 ? 143.128 160.271 155.971 1.00 44.86  ?  133 LEU B CG  1 
ATOM   6456  C  CD1 . LEU B 1 144 ? 142.863 159.024 155.158 1.00 44.86  ?  133 LEU B CD1 1 
ATOM   6457  C  CD2 . LEU B 1 144 ? 144.338 160.983 155.475 1.00 44.86  ?  133 LEU B CD2 1 
ATOM   6458  N  N   . SER B 1 145 ? 140.074 161.990 158.457 1.00 45.92  ?  134 SER B N   1 
ATOM   6459  C  CA  . SER B 1 145 ? 139.980 162.277 159.880 1.00 45.92  ?  134 SER B CA  1 
ATOM   6460  C  C   . SER B 1 145 ? 139.088 161.265 160.582 1.00 45.92  ?  134 SER B C   1 
ATOM   6461  O  O   . SER B 1 145 ? 139.396 160.823 161.694 1.00 45.92  ?  134 SER B O   1 
ATOM   6462  C  CB  . SER B 1 145 ? 139.468 163.693 160.093 1.00 45.92  ?  134 SER B CB  1 
ATOM   6463  O  OG  . SER B 1 145 ? 140.069 164.573 159.173 1.00 45.92  ?  134 SER B OG  1 
ATOM   6464  N  N   . MET B 1 146 ? 137.992 160.864 159.937 1.00 48.65  ?  135 MET B N   1 
ATOM   6465  C  CA  . MET B 1 146 ? 137.163 159.807 160.500 1.00 48.65  ?  135 MET B CA  1 
ATOM   6466  C  C   . MET B 1 146 ? 137.918 158.488 160.581 1.00 48.65  ?  135 MET B C   1 
ATOM   6467  O  O   . MET B 1 146 ? 137.817 157.766 161.578 1.00 48.65  ?  135 MET B O   1 
ATOM   6468  C  CB  . MET B 1 146 ? 135.903 159.643 159.667 1.00 48.65  ?  135 MET B CB  1 
ATOM   6469  C  CG  . MET B 1 146 ? 134.890 160.728 159.870 1.00 48.65  ?  135 MET B CG  1 
ATOM   6470  S  SD  . MET B 1 146 ? 133.283 160.141 159.376 1.00 48.65  ?  135 MET B SD  1 
ATOM   6471  C  CE  . MET B 1 146 ? 133.222 158.613 160.292 1.00 48.65  ?  135 MET B CE  1 
ATOM   6472  N  N   . MET B 1 147 ? 138.667 158.146 159.534 1.00 48.91  ?  136 MET B N   1 
ATOM   6473  C  CA  . MET B 1 147 ? 139.436 156.908 159.556 1.00 48.91  ?  136 MET B CA  1 
ATOM   6474  C  C   . MET B 1 147 ? 140.497 156.927 160.649 1.00 48.91  ?  136 MET B C   1 
ATOM   6475  O  O   . MET B 1 147 ? 140.715 155.919 161.329 1.00 48.91  ?  136 MET B O   1 
ATOM   6476  C  CB  . MET B 1 147 ? 140.075 156.668 158.192 1.00 48.91  ?  136 MET B CB  1 
ATOM   6477  C  CG  . MET B 1 147 ? 139.077 156.392 157.100 1.00 48.91  ?  136 MET B CG  1 
ATOM   6478  S  SD  . MET B 1 147 ? 139.830 156.082 155.505 1.00 48.91  ?  136 MET B SD  1 
ATOM   6479  C  CE  . MET B 1 147 ? 140.476 154.444 155.759 1.00 48.91  ?  136 MET B CE  1 
ATOM   6480  N  N   . VAL B 1 148 ? 141.166 158.061 160.836 1.00 48.43  ?  137 VAL B N   1 
ATOM   6481  C  CA  . VAL B 1 148 ? 142.164 158.172 161.892 1.00 48.43  ?  137 VAL B CA  1 
ATOM   6482  C  C   . VAL B 1 148 ? 141.505 158.076 163.260 1.00 48.43  ?  137 VAL B C   1 
ATOM   6483  O  O   . VAL B 1 148 ? 142.041 157.443 164.171 1.00 48.43  ?  137 VAL B O   1 
ATOM   6484  C  CB  . VAL B 1 148 ? 142.971 159.476 161.739 1.00 48.43  ?  137 VAL B CB  1 
ATOM   6485  C  CG1 . VAL B 1 148 ? 143.845 159.711 162.946 1.00 48.43  ?  137 VAL B CG1 1 
ATOM   6486  C  CG2 . VAL B 1 148 ? 143.819 159.426 160.501 1.00 48.43  ?  137 VAL B CG2 1 
ATOM   6487  N  N   . GLY B 1 149 ? 140.339 158.697 163.431 1.00 50.60  ?  138 GLY B N   1 
ATOM   6488  C  CA  . GLY B 1 149 ? 139.640 158.589 164.700 1.00 50.60  ?  138 GLY B CA  1 
ATOM   6489  C  C   . GLY B 1 149 ? 139.226 157.168 165.026 1.00 50.60  ?  138 GLY B C   1 
ATOM   6490  O  O   . GLY B 1 149 ? 139.309 156.734 166.176 1.00 50.60  ?  138 GLY B O   1 
ATOM   6491  N  N   . LEU B 1 150 ? 138.781 156.419 164.018 1.00 52.08  ?  139 LEU B N   1 
ATOM   6492  C  CA  . LEU B 1 150 ? 138.439 155.020 164.244 1.00 52.08  ?  139 LEU B CA  1 
ATOM   6493  C  C   . LEU B 1 150 ? 139.675 154.186 164.558 1.00 52.08  ?  139 LEU B C   1 
ATOM   6494  O  O   . LEU B 1 150 ? 139.637 153.315 165.436 1.00 52.08  ?  139 LEU B O   1 
ATOM   6495  C  CB  . LEU B 1 150 ? 137.704 154.460 163.031 1.00 52.08  ?  139 LEU B CB  1 
ATOM   6496  C  CG  . LEU B 1 150 ? 136.272 154.959 162.866 1.00 52.08  ?  139 LEU B CG  1 
ATOM   6497  C  CD1 . LEU B 1 150 ? 135.838 154.892 161.418 1.00 52.08  ?  139 LEU B CD1 1 
ATOM   6498  C  CD2 . LEU B 1 150 ? 135.338 154.164 163.742 1.00 52.08  ?  139 LEU B CD2 1 
ATOM   6499  N  N   . ALA B 1 151 ? 140.795 154.461 163.905 1.00 52.41  ?  140 ALA B N   1 
ATOM   6500  C  CA  . ALA B 1 151 ? 142.026 153.740 164.218 1.00 52.41  ?  140 ALA B CA  1 
ATOM   6501  C  C   . ALA B 1 151 ? 142.464 153.971 165.655 1.00 52.41  ?  140 ALA B C   1 
ATOM   6502  O  O   . ALA B 1 151 ? 142.850 153.034 166.344 1.00 52.41  ?  140 ALA B O   1 
ATOM   6503  C  CB  . ALA B 1 151 ? 143.138 154.127 163.257 1.00 52.41  ?  140 ALA B CB  1 
ATOM   6504  N  N   . VAL B 1 152 ? 142.399 155.211 166.115 1.00 54.58  ?  141 VAL B N   1 
ATOM   6505  C  CA  . VAL B 1 152 ? 142.783 155.536 167.483 1.00 54.58  ?  141 VAL B CA  1 
ATOM   6506  C  C   . VAL B 1 152 ? 141.908 154.821 168.496 1.00 54.58  ?  141 VAL B C   1 
ATOM   6507  O  O   . VAL B 1 152 ? 142.406 154.282 169.476 1.00 54.58  ?  141 VAL B O   1 
ATOM   6508  C  CB  . VAL B 1 152 ? 142.709 157.054 167.739 1.00 54.58  ?  141 VAL B CB  1 
ATOM   6509  C  CG1 . VAL B 1 152 ? 142.937 157.367 169.208 1.00 54.58  ?  141 VAL B CG1 1 
ATOM   6510  C  CG2 . VAL B 1 152 ? 143.711 157.787 166.864 1.00 54.58  ?  141 VAL B CG2 1 
ATOM   6511  N  N   . SER B 1 153 ? 140.606 154.804 168.259 1.00 58.59  ?  142 SER B N   1 
ATOM   6512  C  CA  . SER B 1 153 ? 139.694 154.167 169.188 1.00 58.59  ?  142 SER B CA  1 
ATOM   6513  C  C   . SER B 1 153 ? 140.072 152.710 169.366 1.00 58.59  ?  142 SER B C   1 
ATOM   6514  O  O   . SER B 1 153 ? 140.145 152.215 170.488 1.00 58.59  ?  142 SER B O   1 
ATOM   6515  C  CB  . SER B 1 153 ? 138.261 154.296 168.688 1.00 58.59  ?  142 SER B CB  1 
ATOM   6516  O  OG  . SER B 1 153 ? 137.847 155.649 168.674 1.00 58.59  ?  142 SER B OG  1 
ATOM   6517  N  N   . GLY B 1 154 ? 140.340 152.025 168.264 1.00 61.35  ?  143 GLY B N   1 
ATOM   6518  C  CA  . GLY B 1 154 ? 140.731 150.633 168.336 1.00 61.35  ?  143 GLY B CA  1 
ATOM   6519  C  C   . GLY B 1 154 ? 142.063 150.432 169.018 1.00 61.35  ?  143 GLY B C   1 
ATOM   6520  O  O   . GLY B 1 154 ? 142.208 149.543 169.848 1.00 61.35  ?  143 GLY B O   1 
ATOM   6521  N  N   . ALA B 1 155 ? 143.042 151.258 168.680 1.00 62.16  ?  144 ALA B N   1 
ATOM   6522  C  CA  . ALA B 1 155 ? 144.353 151.148 169.292 1.00 62.16  ?  144 ALA B CA  1 
ATOM   6523  C  C   . ALA B 1 155 ? 144.245 151.315 170.785 1.00 62.16  ?  144 ALA B C   1 
ATOM   6524  O  O   . ALA B 1 155 ? 144.882 150.591 171.543 1.00 62.16  ?  144 ALA B O   1 
ATOM   6525  C  CB  . ALA B 1 155 ? 145.288 152.196 168.719 1.00 62.16  ?  144 ALA B CB  1 
ATOM   6526  N  N   . VAL B 1 156 ? 143.438 152.271 171.218 1.00 64.93  ?  145 VAL B N   1 
ATOM   6527  C  CA  . VAL B 1 156 ? 143.297 152.531 172.638 1.00 64.93  ?  145 VAL B CA  1 
ATOM   6528  C  C   . VAL B 1 156 ? 142.711 151.321 173.339 1.00 64.93  ?  145 VAL B C   1 
ATOM   6529  O  O   . VAL B 1 156 ? 143.178 150.930 174.407 1.00 64.93  ?  145 VAL B O   1 
ATOM   6530  C  CB  . VAL B 1 156 ? 142.412 153.763 172.894 1.00 64.93  ?  145 VAL B CB  1 
ATOM   6531  C  CG1 . VAL B 1 156 ? 142.058 153.869 174.368 1.00 64.93  ?  145 VAL B CG1 1 
ATOM   6532  C  CG2 . VAL B 1 156 ? 143.115 155.024 172.417 1.00 64.93  ?  145 VAL B CG2 1 
ATOM   6533  N  N   . SER B 1 157 ? 141.697 150.716 172.736 1.00 66.37  ?  146 SER B N   1 
ATOM   6534  C  CA  . SER B 1 157 ? 141.066 149.553 173.335 1.00 66.37  ?  146 SER B CA  1 
ATOM   6535  C  C   . SER B 1 157 ? 142.029 148.386 173.433 1.00 66.37  ?  146 SER B C   1 
ATOM   6536  O  O   . SER B 1 157 ? 142.094 147.721 174.461 1.00 66.37  ?  146 SER B O   1 
ATOM   6537  C  CB  . SER B 1 157 ? 139.850 149.138 172.512 1.00 66.37  ?  146 SER B CB  1 
ATOM   6538  O  OG  . SER B 1 157 ? 140.238 148.642 171.245 1.00 66.37  ?  146 SER B OG  1 
ATOM   6539  N  N   . LYS B 1 158 ? 142.786 148.137 172.375 1.00 67.80  ?  147 LYS B N   1 
ATOM   6540  C  CA  . LYS B 1 158 ? 143.689 146.991 172.353 1.00 67.80  ?  147 LYS B CA  1 
ATOM   6541  C  C   . LYS B 1 158 ? 144.944 147.194 173.187 1.00 67.80  ?  147 LYS B C   1 
ATOM   6542  O  O   . LYS B 1 158 ? 145.712 146.258 173.392 1.00 67.80  ?  147 LYS B O   1 
ATOM   6543  C  CB  . LYS B 1 158 ? 144.091 146.666 170.918 1.00 67.80  ?  147 LYS B CB  1 
ATOM   6544  C  CG  . LYS B 1 158 ? 142.921 146.493 169.968 1.00 67.80  ?  147 LYS B CG  1 
ATOM   6545  C  CD  . LYS B 1 158 ? 143.412 146.314 168.543 1.00 67.80  ?  147 LYS B CD  1 
ATOM   6546  C  CE  . LYS B 1 158 ? 142.251 146.176 167.575 1.00 67.80  ?  147 LYS B CE  1 
ATOM   6547  N  NZ  . LYS B 1 158 ? 142.725 145.914 166.189 1.00 67.80  1  147 LYS B NZ  1 
ATOM   6548  N  N   . ALA B 1 159 ? 145.166 148.411 173.661 1.00 73.16  ?  148 ALA B N   1 
ATOM   6549  C  CA  . ALA B 1 159 ? 146.327 148.669 174.493 1.00 73.16  ?  148 ALA B CA  1 
ATOM   6550  C  C   . ALA B 1 159 ? 146.175 147.970 175.827 1.00 73.16  ?  148 ALA B C   1 
ATOM   6551  O  O   . ALA B 1 159 ? 145.074 147.898 176.371 1.00 73.16  ?  148 ALA B O   1 
ATOM   6552  C  CB  . ALA B 1 159 ? 146.527 150.157 174.694 1.00 73.16  ?  148 ALA B CB  1 
ATOM   6553  N  N   . VAL B 1 160 ? 147.276 147.452 176.359 1.00 80.28  ?  149 VAL B N   1 
ATOM   6554  C  CA  . VAL B 1 160 ? 147.238 146.767 177.643 1.00 80.28  ?  149 VAL B CA  1 
ATOM   6555  C  C   . VAL B 1 160 ? 147.497 147.768 178.749 1.00 80.28  ?  149 VAL B C   1 
ATOM   6556  O  O   . VAL B 1 160 ? 148.263 148.710 178.567 1.00 80.28  ?  149 VAL B O   1 
ATOM   6557  C  CB  . VAL B 1 160 ? 148.278 145.634 177.706 1.00 80.28  ?  149 VAL B CB  1 
ATOM   6558  C  CG1 . VAL B 1 160 ? 147.973 144.581 176.652 1.00 80.28  ?  149 VAL B CG1 1 
ATOM   6559  C  CG2 . VAL B 1 160 ? 149.681 146.188 177.513 1.00 80.28  ?  149 VAL B CG2 1 
ATOM   6560  N  N   . PRO B 1 161 ? 146.849 147.581 179.905 1.00 82.09  ?  150 PRO B N   1 
ATOM   6561  C  CA  . PRO B 1 161 ? 147.014 148.597 180.946 1.00 82.09  ?  150 PRO B CA  1 
ATOM   6562  C  C   . PRO B 1 161 ? 148.388 148.532 181.602 1.00 82.09  ?  150 PRO B C   1 
ATOM   6563  O  O   . PRO B 1 161 ? 149.103 147.559 181.369 1.00 82.09  ?  150 PRO B O   1 
ATOM   6564  C  CB  . PRO B 1 161 ? 145.908 148.254 181.953 1.00 82.09  ?  150 PRO B CB  1 
ATOM   6565  C  CG  . PRO B 1 161 ? 144.962 147.364 181.211 1.00 82.09  ?  150 PRO B CG  1 
ATOM   6566  C  CD  . PRO B 1 161 ? 145.812 146.601 180.257 1.00 82.09  ?  150 PRO B CD  1 
ATOM   6567  N  N   . LEU B 1 179 ? 139.781 163.874 182.239 1.00 86.10  ?  168 LEU B N   1 
ATOM   6568  C  CA  . LEU B 1 179 ? 139.613 163.523 180.834 1.00 86.10  ?  168 LEU B CA  1 
ATOM   6569  C  C   . LEU B 1 179 ? 140.834 163.908 180.009 1.00 86.10  ?  168 LEU B C   1 
ATOM   6570  O  O   . LEU B 1 179 ? 140.949 163.520 178.845 1.00 86.10  ?  168 LEU B O   1 
ATOM   6571  C  CB  . LEU B 1 179 ? 138.360 164.192 180.274 1.00 86.10  ?  168 LEU B CB  1 
ATOM   6572  C  CG  . LEU B 1 179 ? 137.043 163.678 180.854 1.00 86.10  ?  168 LEU B CG  1 
ATOM   6573  C  CD1 . LEU B 1 179 ? 135.862 164.414 180.241 1.00 86.10  ?  168 LEU B CD1 1 
ATOM   6574  C  CD2 . LEU B 1 179 ? 136.921 162.179 180.625 1.00 86.10  ?  168 LEU B CD2 1 
ATOM   6575  N  N   . LEU B 1 180 ? 141.750 164.660 180.607 1.00 84.23  ?  169 LEU B N   1 
ATOM   6576  C  CA  . LEU B 1 180 ? 142.962 165.049 179.903 1.00 84.23  ?  169 LEU B CA  1 
ATOM   6577  C  C   . LEU B 1 180 ? 143.747 163.825 179.495 1.00 84.23  ?  169 LEU B C   1 
ATOM   6578  O  O   . LEU B 1 180 ? 144.312 163.785 178.409 1.00 84.23  ?  169 LEU B O   1 
ATOM   6579  C  CB  . LEU B 1 180 ? 143.835 165.941 180.779 1.00 84.23  ?  169 LEU B CB  1 
ATOM   6580  C  CG  . LEU B 1 180 ? 145.149 166.389 180.138 1.00 84.23  ?  169 LEU B CG  1 
ATOM   6581  C  CD1 . LEU B 1 180 ? 144.886 167.106 178.822 1.00 84.23  ?  169 LEU B CD1 1 
ATOM   6582  C  CD2 . LEU B 1 180 ? 145.943 167.273 181.087 1.00 84.23  ?  169 LEU B CD2 1 
ATOM   6583  N  N   . ASP B 1 181 ? 143.795 162.827 180.366 1.00 83.08  ?  170 ASP B N   1 
ATOM   6584  C  CA  . ASP B 1 181 ? 144.549 161.616 180.073 1.00 83.08  ?  170 ASP B CA  1 
ATOM   6585  C  C   . ASP B 1 181 ? 143.968 160.907 178.869 1.00 83.08  ?  170 ASP B C   1 
ATOM   6586  O  O   . ASP B 1 181 ? 144.706 160.375 178.048 1.00 83.08  ?  170 ASP B O   1 
ATOM   6587  C  CB  . ASP B 1 181 ? 144.562 160.688 181.282 1.00 83.08  ?  170 ASP B CB  1 
ATOM   6588  C  CG  . ASP B 1 181 ? 145.304 161.283 182.458 1.00 83.08  ?  170 ASP B CG  1 
ATOM   6589  O  OD1 . ASP B 1 181 ? 145.444 160.592 183.488 1.00 83.08  ?  170 ASP B OD1 1 
ATOM   6590  O  OD2 . ASP B 1 181 ? 145.751 162.444 182.351 1.00 83.08  -1 170 ASP B OD2 1 
ATOM   6591  N  N   . ASP B 1 182 ? 142.647 160.893 178.756 1.00 79.84  ?  171 ASP B N   1 
ATOM   6592  C  CA  . ASP B 1 182 ? 142.022 160.294 177.589 1.00 79.84  ?  171 ASP B CA  1 
ATOM   6593  C  C   . ASP B 1 182 ? 142.435 161.053 176.342 1.00 79.84  ?  171 ASP B C   1 
ATOM   6594  O  O   . ASP B 1 182 ? 142.798 160.448 175.338 1.00 79.84  ?  171 ASP B O   1 
ATOM   6595  C  CB  . ASP B 1 182 ? 140.505 160.304 177.730 1.00 79.84  ?  171 ASP B CB  1 
ATOM   6596  C  CG  . ASP B 1 182 ? 140.029 159.520 178.933 1.00 79.84  ?  171 ASP B CG  1 
ATOM   6597  O  OD1 . ASP B 1 182 ? 138.799 159.401 179.117 1.00 79.84  ?  171 ASP B OD1 1 
ATOM   6598  O  OD2 . ASP B 1 182 ? 140.883 159.019 179.694 1.00 79.84  -1 171 ASP B OD2 1 
ATOM   6599  N  N   . GLU B 1 183 ? 142.392 162.378 176.405 1.00 74.79  ?  172 GLU B N   1 
ATOM   6600  C  CA  . GLU B 1 183 ? 142.808 163.188 175.274 1.00 74.79  ?  172 GLU B CA  1 
ATOM   6601  C  C   . GLU B 1 183 ? 144.267 162.959 174.990 1.00 74.79  ?  172 GLU B C   1 
ATOM   6602  O  O   . GLU B 1 183 ? 144.671 162.873 173.837 1.00 74.79  ?  172 GLU B O   1 
ATOM   6603  C  CB  . GLU B 1 183 ? 142.590 164.663 175.572 1.00 74.79  ?  172 GLU B CB  1 
ATOM   6604  C  CG  . GLU B 1 183 ? 141.138 165.070 175.728 1.00 74.79  ?  172 GLU B CG  1 
ATOM   6605  C  CD  . GLU B 1 183 ? 140.994 166.538 176.067 1.00 74.79  ?  172 GLU B CD  1 
ATOM   6606  O  OE1 . GLU B 1 183 ? 139.856 167.048 176.049 1.00 74.79  ?  172 GLU B OE1 1 
ATOM   6607  O  OE2 . GLU B 1 183 ? 142.025 167.183 176.349 1.00 74.79  -1 172 GLU B OE2 1 
ATOM   6608  N  N   . ARG B 1 184 ? 145.066 162.863 176.039 1.00 72.79  ?  173 ARG B N   1 
ATOM   6609  C  CA  . ARG B 1 184 ? 146.489 162.652 175.875 1.00 72.79  ?  173 ARG B CA  1 
ATOM   6610  C  C   . ARG B 1 184 ? 146.760 161.316 175.214 1.00 72.79  ?  173 ARG B C   1 
ATOM   6611  O  O   . ARG B 1 184 ? 147.627 161.210 174.351 1.00 72.79  ?  173 ARG B O   1 
ATOM   6612  C  CB  . ARG B 1 184 ? 147.165 162.725 177.236 1.00 72.79  ?  173 ARG B CB  1 
ATOM   6613  C  CG  . ARG B 1 184 ? 148.661 162.484 177.212 1.00 72.79  ?  173 ARG B CG  1 
ATOM   6614  C  CD  . ARG B 1 184 ? 149.208 162.452 178.627 1.00 72.79  ?  173 ARG B CD  1 
ATOM   6615  N  NE  . ARG B 1 184 ? 148.376 161.628 179.499 1.00 72.79  ?  173 ARG B NE  1 
ATOM   6616  C  CZ  . ARG B 1 184 ? 148.466 160.305 179.582 1.00 72.79  ?  173 ARG B CZ  1 
ATOM   6617  N  NH1 . ARG B 1 184 ? 147.671 159.634 180.404 1.00 72.79  1  173 ARG B NH1 1 
ATOM   6618  N  NH2 . ARG B 1 184 ? 149.347 159.652 178.838 1.00 72.79  ?  173 ARG B NH2 1 
ATOM   6619  N  N   . VAL B 1 185 ? 146.023 160.293 175.613 1.00 65.38  ?  174 VAL B N   1 
ATOM   6620  C  CA  . VAL B 1 185 ? 146.187 158.976 175.023 1.00 65.38  ?  174 VAL B CA  1 
ATOM   6621  C  C   . VAL B 1 185 ? 145.725 158.980 173.578 1.00 65.38  ?  174 VAL B C   1 
ATOM   6622  O  O   . VAL B 1 185 ? 146.334 158.337 172.727 1.00 65.38  ?  174 VAL B O   1 
ATOM   6623  C  CB  . VAL B 1 185 ? 145.404 157.914 175.814 1.00 65.38  ?  174 VAL B CB  1 
ATOM   6624  C  CG1 . VAL B 1 185 ? 145.362 156.599 175.056 1.00 65.38  ?  174 VAL B CG1 1 
ATOM   6625  C  CG2 . VAL B 1 185 ? 146.018 157.727 177.192 1.00 65.38  ?  174 VAL B CG2 1 
ATOM   6626  N  N   . ARG B 1 186 ? 144.651 159.703 173.296 1.00 58.15  ?  175 ARG B N   1 
ATOM   6627  C  CA  . ARG B 1 186 ? 144.147 159.780 171.935 1.00 58.15  ?  175 ARG B CA  1 
ATOM   6628  C  C   . ARG B 1 186 ? 145.077 160.589 171.040 1.00 58.15  ?  175 ARG B C   1 
ATOM   6629  O  O   . ARG B 1 186 ? 145.263 160.254 169.877 1.00 58.15  ?  175 ARG B O   1 
ATOM   6630  C  CB  . ARG B 1 186 ? 142.740 160.375 171.911 1.00 58.15  ?  175 ARG B CB  1 
ATOM   6631  C  CG  . ARG B 1 186 ? 141.662 159.447 172.435 1.00 58.15  ?  175 ARG B CG  1 
ATOM   6632  C  CD  . ARG B 1 186 ? 140.281 159.973 172.086 1.00 58.15  ?  175 ARG B CD  1 
ATOM   6633  N  NE  . ARG B 1 186 ? 140.098 160.097 170.644 1.00 58.15  ?  175 ARG B NE  1 
ATOM   6634  C  CZ  . ARG B 1 186 ? 139.655 159.120 169.860 1.00 58.15  ?  175 ARG B CZ  1 
ATOM   6635  N  NH1 . ARG B 1 186 ? 139.348 157.940 170.377 1.00 58.15  1  175 ARG B NH1 1 
ATOM   6636  N  NH2 . ARG B 1 186 ? 139.521 159.322 168.559 1.00 58.15  ?  175 ARG B NH2 1 
ATOM   6637  N  N   . VAL B 1 187 ? 145.669 161.648 171.581 1.00 56.35  ?  176 VAL B N   1 
ATOM   6638  C  CA  . VAL B 1 187 ? 146.610 162.432 170.792 1.00 56.35  ?  176 VAL B CA  1 
ATOM   6639  C  C   . VAL B 1 187 ? 147.832 161.599 170.442 1.00 56.35  ?  176 VAL B C   1 
ATOM   6640  O  O   . VAL B 1 187 ? 148.312 161.623 169.302 1.00 56.35  ?  176 VAL B O   1 
ATOM   6641  C  CB  . VAL B 1 187 ? 146.991 163.713 171.551 1.00 56.35  ?  176 VAL B CB  1 
ATOM   6642  C  CG1 . VAL B 1 187 ? 148.239 164.325 170.966 1.00 56.35  ?  176 VAL B CG1 1 
ATOM   6643  C  CG2 . VAL B 1 187 ? 145.856 164.695 171.506 1.00 56.35  ?  176 VAL B CG2 1 
ATOM   6644  N  N   . ALA B 1 188 ? 148.349 160.841 171.409 1.00 55.18  ?  177 ALA B N   1 
ATOM   6645  C  CA  . ALA B 1 188 ? 149.503 159.993 171.136 1.00 55.18  ?  177 ALA B CA  1 
ATOM   6646  C  C   . ALA B 1 188 ? 149.176 158.929 170.101 1.00 55.18  ?  177 ALA B C   1 
ATOM   6647  O  O   . ALA B 1 188 ? 149.974 158.668 169.193 1.00 55.18  ?  177 ALA B O   1 
ATOM   6648  C  CB  . ALA B 1 188 ? 149.998 159.353 172.427 1.00 55.18  ?  177 ALA B CB  1 
ATOM   6649  N  N   . ALA B 1 189 ? 148.001 158.309 170.211 1.00 53.61  ?  178 ALA B N   1 
ATOM   6650  C  CA  . ALA B 1 189 ? 147.630 157.274 169.256 1.00 53.61  ?  178 ALA B CA  1 
ATOM   6651  C  C   . ALA B 1 189 ? 147.422 157.853 167.864 1.00 53.61  ?  178 ALA B C   1 
ATOM   6652  O  O   . ALA B 1 189 ? 147.782 157.222 166.867 1.00 53.61  ?  178 ALA B O   1 
ATOM   6653  C  CB  . ALA B 1 189 ? 146.378 156.548 169.729 1.00 53.61  ?  178 ALA B CB  1 
ATOM   6654  N  N   . ALA B 1 190 ? 146.849 159.054 167.773 1.00 50.77  ?  179 ALA B N   1 
ATOM   6655  C  CA  . ALA B 1 190 ? 146.669 159.688 166.472 1.00 50.77  ?  179 ALA B CA  1 
ATOM   6656  C  C   . ALA B 1 190 ? 148.006 160.018 165.832 1.00 50.77  ?  179 ALA B C   1 
ATOM   6657  O  O   . ALA B 1 190 ? 148.197 159.801 164.631 1.00 50.77  ?  179 ALA B O   1 
ATOM   6658  C  CB  . ALA B 1 190 ? 145.820 160.947 166.615 1.00 50.77  ?  179 ALA B CB  1 
ATOM   6659  N  N   . ALA B 1 191 ? 148.945 160.539 166.619 1.00 50.05  ?  180 ALA B N   1 
ATOM   6660  C  CA  . ALA B 1 191 ? 150.269 160.833 166.089 1.00 50.05  ?  180 ALA B CA  1 
ATOM   6661  C  C   . ALA B 1 191 ? 150.972 159.566 165.612 1.00 50.05  ?  180 ALA B C   1 
ATOM   6662  O  O   . ALA B 1 191 ? 151.625 159.566 164.560 1.00 50.05  ?  180 ALA B O   1 
ATOM   6663  C  CB  . ALA B 1 191 ? 151.096 161.552 167.147 1.00 50.05  ?  180 ALA B CB  1 
ATOM   6664  N  N   . SER B 1 192 ? 150.837 158.466 166.358 1.00 52.49  ?  181 SER B N   1 
ATOM   6665  C  CA  . SER B 1 192 ? 151.480 157.224 165.938 1.00 52.49  ?  181 SER B CA  1 
ATOM   6666  C  C   . SER B 1 192 ? 150.844 156.664 164.675 1.00 52.49  ?  181 SER B C   1 
ATOM   6667  O  O   . SER B 1 192 ? 151.548 156.164 163.787 1.00 52.49  ?  181 SER B O   1 
ATOM   6668  C  CB  . SER B 1 192 ? 151.425 156.196 167.061 1.00 52.49  ?  181 SER B CB  1 
ATOM   6669  O  OG  . SER B 1 192 ? 152.089 156.675 168.211 1.00 52.49  ?  181 SER B OG  1 
ATOM   6670  N  N   . VAL B 1 193 ? 149.514 156.711 164.588 1.00 48.11  ?  182 VAL B N   1 
ATOM   6671  C  CA  . VAL B 1 193 ? 148.827 156.260 163.385 1.00 48.11  ?  182 VAL B CA  1 
ATOM   6672  C  C   . VAL B 1 193 ? 149.281 157.074 162.184 1.00 48.11  ?  182 VAL B C   1 
ATOM   6673  O  O   . VAL B 1 193 ? 149.506 156.535 161.094 1.00 48.11  ?  182 VAL B O   1 
ATOM   6674  C  CB  . VAL B 1 193 ? 147.304 156.344 163.592 1.00 48.11  ?  182 VAL B CB  1 
ATOM   6675  C  CG1 . VAL B 1 193 ? 146.578 156.297 162.275 1.00 48.11  ?  182 VAL B CG1 1 
ATOM   6676  C  CG2 . VAL B 1 193 ? 146.837 155.230 164.496 1.00 48.11  ?  182 VAL B CG2 1 
ATOM   6677  N  N   . THR B 1 194 ? 149.448 158.381 162.373 1.00 47.33  ?  183 THR B N   1 
ATOM   6678  C  CA  . THR B 1 194 ? 149.921 159.243 161.299 1.00 47.33  ?  183 THR B CA  1 
ATOM   6679  C  C   . THR B 1 194 ? 151.323 158.864 160.853 1.00 47.33  ?  183 THR B C   1 
ATOM   6680  O  O   . THR B 1 194 ? 151.602 158.796 159.651 1.00 47.33  ?  183 THR B O   1 
ATOM   6681  C  CB  . THR B 1 194 ? 149.885 160.687 161.767 1.00 47.33  ?  183 THR B CB  1 
ATOM   6682  O  OG1 . THR B 1 194 ? 148.608 160.943 162.349 1.00 47.33  ?  183 THR B OG1 1 
ATOM   6683  C  CG2 . THR B 1 194 ? 150.124 161.626 160.624 1.00 47.33  ?  183 THR B CG2 1 
ATOM   6684  N  N   . VAL B 1 195 ? 152.224 158.623 161.804 1.00 47.96  ?  184 VAL B N   1 
ATOM   6685  C  CA  . VAL B 1 195 ? 153.589 158.262 161.438 1.00 47.96  ?  184 VAL B CA  1 
ATOM   6686  C  C   . VAL B 1 195 ? 153.614 156.940 160.681 1.00 47.96  ?  184 VAL B C   1 
ATOM   6687  O  O   . VAL B 1 195 ? 154.340 156.794 159.694 1.00 47.96  ?  184 VAL B O   1 
ATOM   6688  C  CB  . VAL B 1 195 ? 154.496 158.220 162.678 1.00 47.96  ?  184 VAL B CB  1 
ATOM   6689  C  CG1 . VAL B 1 195 ? 155.867 157.734 162.295 1.00 47.96  ?  184 VAL B CG1 1 
ATOM   6690  C  CG2 . VAL B 1 195 ? 154.602 159.580 163.291 1.00 47.96  ?  184 VAL B CG2 1 
ATOM   6691  N  N   . LEU B 1 196 ? 152.821 155.960 161.113 1.00 48.52  ?  185 LEU B N   1 
ATOM   6692  C  CA  . LEU B 1 196 ? 152.847 154.678 160.417 1.00 48.52  ?  185 LEU B CA  1 
ATOM   6693  C  C   . LEU B 1 196 ? 152.228 154.781 159.027 1.00 48.52  ?  185 LEU B C   1 
ATOM   6694  O  O   . LEU B 1 196 ? 152.706 154.146 158.080 1.00 48.52  ?  185 LEU B O   1 
ATOM   6695  C  CB  . LEU B 1 196 ? 152.146 153.608 161.243 1.00 48.52  ?  185 LEU B CB  1 
ATOM   6696  C  CG  . LEU B 1 196 ? 152.229 152.200 160.655 1.00 48.52  ?  185 LEU B CG  1 
ATOM   6697  C  CD1 . LEU B 1 196 ? 153.663 151.809 160.395 1.00 48.52  ?  185 LEU B CD1 1 
ATOM   6698  C  CD2 . LEU B 1 196 ? 151.559 151.205 161.559 1.00 48.52  ?  185 LEU B CD2 1 
ATOM   6699  N  N   . SER B 1 197 ? 151.170 155.579 158.876 1.00 46.83  ?  186 SER B N   1 
ATOM   6700  C  CA  . SER B 1 197 ? 150.608 155.812 157.550 1.00 46.83  ?  186 SER B CA  1 
ATOM   6701  C  C   . SER B 1 197 ? 151.626 156.474 156.636 1.00 46.83  ?  186 SER B C   1 
ATOM   6702  O  O   . SER B 1 197 ? 151.757 156.101 155.466 1.00 46.83  ?  186 SER B O   1 
ATOM   6703  C  CB  . SER B 1 197 ? 149.356 156.674 157.655 1.00 46.83  ?  186 SER B CB  1 
ATOM   6704  O  OG  . SER B 1 197 ? 148.443 156.106 158.564 1.00 46.83  ?  186 SER B OG  1 
ATOM   6705  N  N   . GLY B 1 198 ? 152.365 157.455 157.154 1.00 45.24  ?  187 GLY B N   1 
ATOM   6706  C  CA  . GLY B 1 198 ? 153.391 158.090 156.351 1.00 45.24  ?  187 GLY B CA  1 
ATOM   6707  C  C   . GLY B 1 198 ? 154.512 157.142 155.981 1.00 45.24  ?  187 GLY B C   1 
ATOM   6708  O  O   . GLY B 1 198 ? 155.047 157.209 154.877 1.00 45.24  ?  187 GLY B O   1 
ATOM   6709  N  N   . ILE B 1 199 ? 154.883 156.250 156.898 1.00 45.52  ?  188 ILE B N   1 
ATOM   6710  C  CA  . ILE B 1 199 ? 155.909 155.258 156.600 1.00 45.52  ?  188 ILE B CA  1 
ATOM   6711  C  C   . ILE B 1 199 ? 155.451 154.337 155.480 1.00 45.52  ?  188 ILE B C   1 
ATOM   6712  O  O   . ILE B 1 199 ? 156.220 154.018 154.568 1.00 45.52  ?  188 ILE B O   1 
ATOM   6713  C  CB  . ILE B 1 199 ? 156.270 154.468 157.869 1.00 45.52  ?  188 ILE B CB  1 
ATOM   6714  C  CG1 . ILE B 1 199 ? 157.109 155.321 158.808 1.00 45.52  ?  188 ILE B CG1 1 
ATOM   6715  C  CG2 . ILE B 1 199 ? 157.024 153.214 157.519 1.00 45.52  ?  188 ILE B CG2 1 
ATOM   6716  C  CD1 . ILE B 1 199 ? 157.267 154.727 160.160 1.00 45.52  ?  188 ILE B CD1 1 
ATOM   6717  N  N   . ILE B 1 200 ? 154.193 153.905 155.521 1.00 46.90  ?  189 ILE B N   1 
ATOM   6718  C  CA  . ILE B 1 200 ? 153.678 153.033 154.470 1.00 46.90  ?  189 ILE B CA  1 
ATOM   6719  C  C   . ILE B 1 200 ? 153.643 153.762 153.132 1.00 46.90  ?  189 ILE B C   1 
ATOM   6720  O  O   . ILE B 1 200 ? 154.006 153.199 152.093 1.00 46.90  ?  189 ILE B O   1 
ATOM   6721  C  CB  . ILE B 1 200 ? 152.293 152.493 154.864 1.00 46.90  ?  189 ILE B CB  1 
ATOM   6722  C  CG1 . ILE B 1 200 ? 152.415 151.572 156.070 1.00 46.90  ?  189 ILE B CG1 1 
ATOM   6723  C  CG2 . ILE B 1 200 ? 151.649 151.766 153.708 1.00 46.90  ?  189 ILE B CG2 1 
ATOM   6724  C  CD1 . ILE B 1 200 ? 151.109 151.240 156.705 1.00 46.90  ?  189 ILE B CD1 1 
ATOM   6725  N  N   . GLN B 1 201 ? 153.220 155.027 153.134 1.00 45.55  ?  190 GLN B N   1 
ATOM   6726  C  CA  . GLN B 1 201 ? 153.196 155.799 151.895 1.00 45.55  ?  190 GLN B CA  1 
ATOM   6727  C  C   . GLN B 1 201 ? 154.595 155.987 151.329 1.00 45.55  ?  190 GLN B C   1 
ATOM   6728  O  O   . GLN B 1 201 ? 154.813 155.835 150.124 1.00 45.55  ?  190 GLN B O   1 
ATOM   6729  C  CB  . GLN B 1 201 ? 152.543 157.156 152.136 1.00 45.55  ?  190 GLN B CB  1 
ATOM   6730  C  CG  . GLN B 1 201 ? 151.049 157.126 152.130 1.00 45.55  ?  190 GLN B CG  1 
ATOM   6731  C  CD  . GLN B 1 201 ? 150.448 158.434 152.554 1.00 45.55  ?  190 GLN B CD  1 
ATOM   6732  O  OE1 . GLN B 1 201 ? 150.815 158.992 153.579 1.00 45.55  ?  190 GLN B OE1 1 
ATOM   6733  N  NE2 . GLN B 1 201 ? 149.514 158.932 151.770 1.00 45.55  ?  190 GLN B NE2 1 
ATOM   6734  N  N   . LEU B 1 202 ? 155.555 156.324 152.185 1.00 47.22  ?  191 LEU B N   1 
ATOM   6735  C  CA  . LEU B 1 202 ? 156.925 156.513 151.737 1.00 47.22  ?  191 LEU B CA  1 
ATOM   6736  C  C   . LEU B 1 202 ? 157.511 155.221 151.189 1.00 47.22  ?  191 LEU B C   1 
ATOM   6737  O  O   . LEU B 1 202 ? 158.231 155.236 150.186 1.00 47.22  ?  191 LEU B O   1 
ATOM   6738  C  CB  . LEU B 1 202 ? 157.769 157.043 152.891 1.00 47.22  ?  191 LEU B CB  1 
ATOM   6739  C  CG  . LEU B 1 202 ? 159.249 157.274 152.642 1.00 47.22  ?  191 LEU B CG  1 
ATOM   6740  C  CD1 . LEU B 1 202 ? 159.446 158.337 151.592 1.00 47.22  ?  191 LEU B CD1 1 
ATOM   6741  C  CD2 . LEU B 1 202 ? 159.909 157.674 153.929 1.00 47.22  ?  191 LEU B CD2 1 
ATOM   6742  N  N   . ALA B 1 203 ? 157.213 154.092 151.831 1.00 47.67  ?  192 ALA B N   1 
ATOM   6743  C  CA  . ALA B 1 203 ? 157.697 152.813 151.328 1.00 47.67  ?  192 ALA B CA  1 
ATOM   6744  C  C   . ALA B 1 203 ? 157.111 152.510 149.960 1.00 47.67  ?  192 ALA B C   1 
ATOM   6745  O  O   . ALA B 1 203 ? 157.828 152.095 149.046 1.00 47.67  ?  192 ALA B O   1 
ATOM   6746  C  CB  . ALA B 1 203 ? 157.360 151.699 152.313 1.00 47.67  ?  192 ALA B CB  1 
ATOM   6747  N  N   . PHE B 1 204 ? 155.805 152.719 149.797 1.00 50.08  ?  193 PHE B N   1 
ATOM   6748  C  CA  . PHE B 1 204 ? 155.181 152.490 148.499 1.00 50.08  ?  193 PHE B CA  1 
ATOM   6749  C  C   . PHE B 1 204 ? 155.738 153.416 147.432 1.00 50.08  ?  193 PHE B C   1 
ATOM   6750  O  O   . PHE B 1 204 ? 155.787 153.046 146.257 1.00 50.08  ?  193 PHE B O   1 
ATOM   6751  C  CB  . PHE B 1 204 ? 153.673 152.670 148.604 1.00 50.08  ?  193 PHE B CB  1 
ATOM   6752  C  CG  . PHE B 1 204 ? 152.931 151.398 148.829 1.00 50.08  ?  193 PHE B CG  1 
ATOM   6753  C  CD1 . PHE B 1 204 ? 153.024 150.735 150.035 1.00 50.08  ?  193 PHE B CD1 1 
ATOM   6754  C  CD2 . PHE B 1 204 ? 152.141 150.863 147.835 1.00 50.08  ?  193 PHE B CD2 1 
ATOM   6755  C  CE1 . PHE B 1 204 ? 152.344 149.568 150.248 1.00 50.08  ?  193 PHE B CE1 1 
ATOM   6756  C  CE2 . PHE B 1 204 ? 151.456 149.690 148.044 1.00 50.08  ?  193 PHE B CE2 1 
ATOM   6757  C  CZ  . PHE B 1 204 ? 151.559 149.043 149.254 1.00 50.08  ?  193 PHE B CZ  1 
ATOM   6758  N  N   . GLY B 1 205 ? 156.141 154.627 147.812 1.00 50.39  ?  194 GLY B N   1 
ATOM   6759  C  CA  . GLY B 1 205 ? 156.708 155.544 146.843 1.00 50.39  ?  194 GLY B CA  1 
ATOM   6760  C  C   . GLY B 1 205 ? 158.131 155.221 146.462 1.00 50.39  ?  194 GLY B C   1 
ATOM   6761  O  O   . GLY B 1 205 ? 158.537 155.459 145.323 1.00 50.39  ?  194 GLY B O   1 
ATOM   6762  N  N   . ILE B 1 206 ? 158.910 154.684 147.398 1.00 50.96  ?  195 ILE B N   1 
ATOM   6763  C  CA  . ILE B 1 206 ? 160.273 154.275 147.085 1.00 50.96  ?  195 ILE B CA  1 
ATOM   6764  C  C   . ILE B 1 206 ? 160.269 153.012 146.231 1.00 50.96  ?  195 ILE B C   1 
ATOM   6765  O  O   . ILE B 1 206 ? 161.119 152.840 145.352 1.00 50.96  ?  195 ILE B O   1 
ATOM   6766  C  CB  . ILE B 1 206 ? 161.074 154.092 148.386 1.00 50.96  ?  195 ILE B CB  1 
ATOM   6767  C  CG1 . ILE B 1 206 ? 161.363 155.449 149.021 1.00 50.96  ?  195 ILE B CG1 1 
ATOM   6768  C  CG2 . ILE B 1 206 ? 162.360 153.346 148.135 1.00 50.96  ?  195 ILE B CG2 1 
ATOM   6769  C  CD1 . ILE B 1 206 ? 161.711 155.366 150.477 1.00 50.96  ?  195 ILE B CD1 1 
ATOM   6770  N  N   . LEU B 1 207 ? 159.310 152.120 146.461 1.00 50.84  ?  196 LEU B N   1 
ATOM   6771  C  CA  . LEU B 1 207 ? 159.181 150.900 145.677 1.00 50.84  ?  196 LEU B CA  1 
ATOM   6772  C  C   . LEU B 1 207 ? 158.503 151.118 144.334 1.00 50.84  ?  196 LEU B C   1 
ATOM   6773  O  O   . LEU B 1 207 ? 158.269 150.142 143.620 1.00 50.84  ?  196 LEU B O   1 
ATOM   6774  C  CB  . LEU B 1 207 ? 158.406 149.845 146.462 1.00 50.84  ?  196 LEU B CB  1 
ATOM   6775  C  CG  . LEU B 1 207 ? 159.023 149.350 147.765 1.00 50.84  ?  196 LEU B CG  1 
ATOM   6776  C  CD1 . LEU B 1 207 ? 158.087 148.386 148.451 1.00 50.84  ?  196 LEU B CD1 1 
ATOM   6777  C  CD2 . LEU B 1 207 ? 160.355 148.697 147.506 1.00 50.84  ?  196 LEU B CD2 1 
ATOM   6778  N  N   . ARG B 1 208 ? 158.172 152.360 143.986 1.00 50.57  ?  197 ARG B N   1 
ATOM   6779  C  CA  . ARG B 1 208 ? 157.625 152.724 142.677 1.00 50.57  ?  197 ARG B CA  1 
ATOM   6780  C  C   . ARG B 1 208 ? 156.303 152.013 142.397 1.00 50.57  ?  197 ARG B C   1 
ATOM   6781  O  O   . ARG B 1 208 ? 156.067 151.503 141.303 1.00 50.57  ?  197 ARG B O   1 
ATOM   6782  C  CB  . ARG B 1 208 ? 158.624 152.462 141.546 1.00 50.57  ?  197 ARG B CB  1 
ATOM   6783  C  CG  . ARG B 1 208 ? 160.087 152.717 141.857 1.00 50.57  ?  197 ARG B CG  1 
ATOM   6784  C  CD  . ARG B 1 208 ? 160.327 154.037 142.548 1.00 50.57  ?  197 ARG B CD  1 
ATOM   6785  N  NE  . ARG B 1 208 ? 160.194 155.184 141.669 1.00 50.57  ?  197 ARG B NE  1 
ATOM   6786  C  CZ  . ARG B 1 208 ? 160.211 156.437 142.100 1.00 50.57  ?  197 ARG B CZ  1 
ATOM   6787  N  NH1 . ARG B 1 208 ? 160.351 156.688 143.391 1.00 50.57  1  197 ARG B NH1 1 
ATOM   6788  N  NH2 . ARG B 1 208 ? 160.083 157.436 141.245 1.00 50.57  ?  197 ARG B NH2 1 
ATOM   6789  N  N   . ILE B 1 209 ? 155.420 152.000 143.392 1.00 51.23  ?  198 ILE B N   1 
ATOM   6790  C  CA  . ILE B 1 209 ? 154.117 151.364 143.230 1.00 51.23  ?  198 ILE B CA  1 
ATOM   6791  C  C   . ILE B 1 209 ? 152.996 152.386 143.270 1.00 51.23  ?  198 ILE B C   1 
ATOM   6792  O  O   . ILE B 1 209 ? 151.986 152.169 143.925 1.00 51.23  ?  198 ILE B O   1 
ATOM   6793  C  CB  . ILE B 1 209 ? 153.855 150.332 144.338 1.00 51.23  ?  198 ILE B CB  1 
ATOM   6794  C  CG1 . ILE B 1 209 ? 155.167 149.767 144.876 1.00 51.23  ?  198 ILE B CG1 1 
ATOM   6795  C  CG2 . ILE B 1 209 ? 152.960 149.215 143.822 1.00 51.23  ?  198 ILE B CG2 1 
ATOM   6796  C  CD1 . ILE B 1 209 ? 154.973 148.794 146.016 1.00 51.23  ?  198 ILE B CD1 1 
ATOM   6797  N  N   . GLY B 1 210 ? 153.159 153.495 142.564 1.00 50.98  ?  199 GLY B N   1 
ATOM   6798  C  CA  . GLY B 1 210 ? 152.160 154.546 142.578 1.00 50.98  ?  199 GLY B CA  1 
ATOM   6799  C  C   . GLY B 1 210 ? 151.029 154.295 141.614 1.00 50.98  ?  199 GLY B C   1 
ATOM   6800  O  O   . GLY B 1 210 ? 150.133 155.121 141.479 1.00 50.98  ?  199 GLY B O   1 
ATOM   6801  N  N   . PHE B 1 211 ? 151.063 153.158 140.940 1.00 47.32  ?  200 PHE B N   1 
ATOM   6802  C  CA  . PHE B 1 211 ? 150.023 152.815 139.989 1.00 47.32  ?  200 PHE B CA  1 
ATOM   6803  C  C   . PHE B 1 211 ? 148.887 152.069 140.667 1.00 47.32  ?  200 PHE B C   1 
ATOM   6804  O  O   . PHE B 1 211 ? 147.922 151.694 140.020 1.00 47.32  ?  200 PHE B O   1 
ATOM   6805  C  CB  . PHE B 1 211 ? 150.611 151.971 138.858 1.00 47.32  ?  200 PHE B CB  1 
ATOM   6806  C  CG  . PHE B 1 211 ? 151.279 150.713 139.325 1.00 47.32  ?  200 PHE B CG  1 
ATOM   6807  C  CD1 . PHE B 1 211 ? 152.647 150.676 139.523 1.00 47.32  ?  200 PHE B CD1 1 
ATOM   6808  C  CD2 . PHE B 1 211 ? 150.541 149.569 139.566 1.00 47.32  ?  200 PHE B CD2 1 
ATOM   6809  C  CE1 . PHE B 1 211 ? 153.267 149.521 139.951 1.00 47.32  ?  200 PHE B CE1 1 
ATOM   6810  C  CE2 . PHE B 1 211 ? 151.153 148.411 139.997 1.00 47.32  ?  200 PHE B CE2 1 
ATOM   6811  C  CZ  . PHE B 1 211 ? 152.519 148.387 140.189 1.00 47.32  ?  200 PHE B CZ  1 
ATOM   6812  N  N   . VAL B 1 212 ? 148.992 151.862 141.972 1.00 48.72  ?  201 VAL B N   1 
ATOM   6813  C  CA  . VAL B 1 212 ? 147.942 151.170 142.715 1.00 48.72  ?  201 VAL B CA  1 
ATOM   6814  C  C   . VAL B 1 212 ? 146.622 151.911 142.615 1.00 48.72  ?  201 VAL B C   1 
ATOM   6815  O  O   . VAL B 1 212 ? 145.565 151.332 142.832 1.00 48.72  ?  201 VAL B O   1 
ATOM   6816  C  CB  . VAL B 1 212 ? 148.316 151.003 144.197 1.00 48.72  ?  201 VAL B CB  1 
ATOM   6817  C  CG1 . VAL B 1 212 ? 149.456 150.010 144.341 1.00 48.72  ?  201 VAL B CG1 1 
ATOM   6818  C  CG2 . VAL B 1 212 ? 148.682 152.346 144.809 1.00 48.72  ?  201 VAL B CG2 1 
ATOM   6819  N  N   . VAL B 1 213 ? 146.677 153.191 142.287 1.00 47.49  ?  202 VAL B N   1 
ATOM   6820  C  CA  . VAL B 1 213 ? 145.465 153.976 142.120 1.00 47.49  ?  202 VAL B CA  1 
ATOM   6821  C  C   . VAL B 1 213 ? 144.560 153.416 141.032 1.00 47.49  ?  202 VAL B C   1 
ATOM   6822  O  O   . VAL B 1 213 ? 143.362 153.673 141.036 1.00 47.49  ?  202 VAL B O   1 
ATOM   6823  C  CB  . VAL B 1 213 ? 145.815 155.432 141.774 1.00 47.49  ?  202 VAL B CB  1 
ATOM   6824  C  CG1 . VAL B 1 213 ? 146.223 156.195 143.023 1.00 47.49  ?  202 VAL B CG1 1 
ATOM   6825  C  CG2 . VAL B 1 213 ? 146.902 155.485 140.714 1.00 47.49  ?  202 VAL B CG2 1 
ATOM   6826  N  N   . ILE B 1 214 ? 145.126 152.663 140.098 1.00 46.29  ?  203 ILE B N   1 
ATOM   6827  C  CA  . ILE B 1 214 ? 144.351 152.105 138.992 1.00 46.29  ?  203 ILE B CA  1 
ATOM   6828  C  C   . ILE B 1 214 ? 143.412 151.005 139.440 1.00 46.29  ?  203 ILE B C   1 
ATOM   6829  O  O   . ILE B 1 214 ? 142.470 150.672 138.733 1.00 46.29  ?  203 ILE B O   1 
ATOM   6830  C  CB  . ILE B 1 214 ? 145.272 151.530 137.899 1.00 46.29  ?  203 ILE B CB  1 
ATOM   6831  C  CG1 . ILE B 1 214 ? 145.925 150.235 138.390 1.00 46.29  ?  203 ILE B CG1 1 
ATOM   6832  C  CG2 . ILE B 1 214 ? 146.314 152.556 137.484 1.00 46.29  ?  203 ILE B CG2 1 
ATOM   6833  C  CD1 . ILE B 1 214 ? 146.874 149.612 137.395 1.00 46.29  ?  203 ILE B CD1 1 
ATOM   6834  N  N   . TYR B 1 215 ? 143.655 150.445 140.616 1.00 46.12  ?  204 TYR B N   1 
ATOM   6835  C  CA  . TYR B 1 215 ? 142.838 149.347 141.105 1.00 46.12  ?  204 TYR B CA  1 
ATOM   6836  C  C   . TYR B 1 215 ? 141.524 149.839 141.670 1.00 46.12  ?  204 TYR B C   1 
ATOM   6837  O  O   . TYR B 1 215 ? 140.723 149.050 142.152 1.00 46.12  ?  204 TYR B O   1 
ATOM   6838  C  CB  . TYR B 1 215 ? 143.607 148.555 142.154 1.00 46.12  ?  204 TYR B CB  1 
ATOM   6839  C  CG  . TYR B 1 215 ? 144.884 147.942 141.637 1.00 46.12  ?  204 TYR B CG  1 
ATOM   6840  C  CD1 . TYR B 1 215 ? 146.115 148.356 142.114 1.00 46.12  ?  204 TYR B CD1 1 
ATOM   6841  C  CD2 . TYR B 1 215 ? 144.857 146.952 140.668 1.00 46.12  ?  204 TYR B CD2 1 
ATOM   6842  C  CE1 . TYR B 1 215 ? 147.286 147.800 141.646 1.00 46.12  ?  204 TYR B CE1 1 
ATOM   6843  C  CE2 . TYR B 1 215 ? 146.023 146.388 140.193 1.00 46.12  ?  204 TYR B CE2 1 
ATOM   6844  C  CZ  . TYR B 1 215 ? 147.233 146.818 140.687 1.00 46.12  ?  204 TYR B CZ  1 
ATOM   6845  O  OH  . TYR B 1 215 ? 148.397 146.261 140.220 1.00 46.12  ?  204 TYR B OH  1 
ATOM   6846  N  N   . LEU B 1 216 ? 141.292 151.139 141.609 1.00 46.38  ?  205 LEU B N   1 
ATOM   6847  C  CA  . LEU B 1 216 ? 140.036 151.697 142.078 1.00 46.38  ?  205 LEU B CA  1 
ATOM   6848  C  C   . LEU B 1 216 ? 139.221 152.232 140.915 1.00 46.38  ?  205 LEU B C   1 
ATOM   6849  O  O   . LEU B 1 216 ? 139.633 153.179 140.259 1.00 46.38  ?  205 LEU B O   1 
ATOM   6850  C  CB  . LEU B 1 216 ? 140.308 152.806 143.089 1.00 46.38  ?  205 LEU B CB  1 
ATOM   6851  C  CG  . LEU B 1 216 ? 141.207 152.449 144.271 1.00 46.38  ?  205 LEU B CG  1 
ATOM   6852  C  CD1 . LEU B 1 216 ? 141.534 153.695 145.076 1.00 46.38  ?  205 LEU B CD1 1 
ATOM   6853  C  CD2 . LEU B 1 216 ? 140.557 151.390 145.146 1.00 46.38  ?  205 LEU B CD2 1 
ATOM   6854  N  N   . SER B 1 217 ? 138.068 151.634 140.656 1.00 46.42  ?  206 SER B N   1 
ATOM   6855  C  CA  . SER B 1 217 ? 137.213 152.068 139.557 1.00 46.42  ?  206 SER B CA  1 
ATOM   6856  C  C   . SER B 1 217 ? 136.447 153.322 139.931 1.00 46.42  ?  206 SER B C   1 
ATOM   6857  O  O   . SER B 1 217 ? 136.481 153.751 141.078 1.00 46.42  ?  206 SER B O   1 
ATOM   6858  C  CB  . SER B 1 217 ? 136.231 150.964 139.174 1.00 46.42  ?  206 SER B CB  1 
ATOM   6859  O  OG  . SER B 1 217 ? 135.378 150.635 140.253 1.00 46.42  ?  206 SER B OG  1 
ATOM   6860  N  N   . GLU B 1 218 ? 135.745 153.907 138.971 1.00 49.49  ?  207 GLU B N   1 
ATOM   6861  C  CA  . GLU B 1 218 ? 134.945 155.079 139.287 1.00 49.49  ?  207 GLU B CA  1 
ATOM   6862  C  C   . GLU B 1 218 ? 133.686 154.710 140.051 1.00 49.49  ?  207 GLU B C   1 
ATOM   6863  O  O   . GLU B 1 218 ? 133.228 155.489 140.888 1.00 49.49  ?  207 GLU B O   1 
ATOM   6864  C  CB  . GLU B 1 218 ? 134.588 155.832 138.010 1.00 49.49  ?  207 GLU B CB  1 
ATOM   6865  C  CG  . GLU B 1 218 ? 135.776 156.426 137.299 1.00 49.49  ?  207 GLU B CG  1 
ATOM   6866  C  CD  . GLU B 1 218 ? 135.440 156.881 135.900 1.00 49.49  ?  207 GLU B CD  1 
ATOM   6867  O  OE1 . GLU B 1 218 ? 136.327 157.440 135.225 1.00 49.49  ?  207 GLU B OE1 1 
ATOM   6868  O  OE2 . GLU B 1 218 ? 134.282 156.680 135.477 1.00 49.49  -1 207 GLU B OE2 1 
ATOM   6869  N  N   . SER B 1 219 ? 133.111 153.539 139.779 1.00 46.62  ?  208 SER B N   1 
ATOM   6870  C  CA  . SER B 1 219 ? 131.936 153.102 140.523 1.00 46.62  ?  208 SER B CA  1 
ATOM   6871  C  C   . SER B 1 219 ? 132.280 152.829 141.975 1.00 46.62  ?  208 SER B C   1 
ATOM   6872  O  O   . SER B 1 219 ? 131.515 153.181 142.879 1.00 46.62  ?  208 SER B O   1 
ATOM   6873  C  CB  . SER B 1 219 ? 131.343 151.854 139.883 1.00 46.62  ?  208 SER B CB  1 
ATOM   6874  O  OG  . SER B 1 219 ? 131.370 151.961 138.482 1.00 46.62  ?  208 SER B OG  1 
ATOM   6875  N  N   . LEU B 1 220 ? 133.428 152.199 142.215 1.00 45.31  ?  209 LEU B N   1 
ATOM   6876  C  CA  . LEU B 1 220 ? 133.874 151.978 143.580 1.00 45.31  ?  209 LEU B CA  1 
ATOM   6877  C  C   . LEU B 1 220 ? 134.088 153.296 144.301 1.00 45.31  ?  209 LEU B C   1 
ATOM   6878  O  O   . LEU B 1 220 ? 133.676 153.451 145.451 1.00 45.31  ?  209 LEU B O   1 
ATOM   6879  C  CB  . LEU B 1 220 ? 135.153 151.148 143.589 1.00 45.31  ?  209 LEU B CB  1 
ATOM   6880  C  CG  . LEU B 1 220 ? 135.688 150.737 144.956 1.00 45.31  ?  209 LEU B CG  1 
ATOM   6881  C  CD1 . LEU B 1 220 ? 136.218 149.341 144.905 1.00 45.31  ?  209 LEU B CD1 1 
ATOM   6882  C  CD2 . LEU B 1 220 ? 136.771 151.678 145.411 1.00 45.31  ?  209 LEU B CD2 1 
ATOM   6883  N  N   . ILE B 1 221 ? 134.733 154.256 143.644 1.00 44.36  ?  210 ILE B N   1 
ATOM   6884  C  CA  . ILE B 1 221 ? 135.003 155.534 144.288 1.00 44.36  ?  210 ILE B CA  1 
ATOM   6885  C  C   . ILE B 1 221 ? 133.706 156.271 144.577 1.00 44.36  ?  210 ILE B C   1 
ATOM   6886  O  O   . ILE B 1 221 ? 133.539 156.859 145.647 1.00 44.36  ?  210 ILE B O   1 
ATOM   6887  C  CB  . ILE B 1 221 ? 135.961 156.370 143.423 1.00 44.36  ?  210 ILE B CB  1 
ATOM   6888  C  CG1 . ILE B 1 221 ? 137.360 155.771 143.469 1.00 44.36  ?  210 ILE B CG1 1 
ATOM   6889  C  CG2 . ILE B 1 221 ? 136.003 157.795 143.900 1.00 44.36  ?  210 ILE B CG2 1 
ATOM   6890  C  CD1 . ILE B 1 221 ? 138.244 156.228 142.354 1.00 44.36  ?  210 ILE B CD1 1 
ATOM   6891  N  N   . SER B 1 222 ? 132.758 156.230 143.644 1.00 45.19  ?  211 SER B N   1 
ATOM   6892  C  CA  . SER B 1 222 ? 131.479 156.897 143.847 1.00 45.19  ?  211 SER B CA  1 
ATOM   6893  C  C   . SER B 1 222 ? 130.715 156.291 145.018 1.00 45.19  ?  211 SER B C   1 
ATOM   6894  O  O   . SER B 1 222 ? 130.230 157.012 145.898 1.00 45.19  ?  211 SER B O   1 
ATOM   6895  C  CB  . SER B 1 222 ? 130.659 156.822 142.564 1.00 45.19  ?  211 SER B CB  1 
ATOM   6896  O  OG  . SER B 1 222 ? 129.635 157.788 142.549 1.00 45.19  ?  211 SER B OG  1 
ATOM   6897  N  N   . GLY B 1 223 ? 130.597 154.963 145.049 1.00 44.07  ?  212 GLY B N   1 
ATOM   6898  C  CA  . GLY B 1 223 ? 129.889 154.324 146.143 1.00 44.07  ?  212 GLY B CA  1 
ATOM   6899  C  C   . GLY B 1 223 ? 130.574 154.531 147.475 1.00 44.07  ?  212 GLY B C   1 
ATOM   6900  O  O   . GLY B 1 223 ? 129.923 154.798 148.489 1.00 44.07  ?  212 GLY B O   1 
ATOM   6901  N  N   . PHE B 1 224 ? 131.903 154.449 147.485 1.00 44.75  ?  213 PHE B N   1 
ATOM   6902  C  CA  . PHE B 1 224 ? 132.653 154.632 148.714 1.00 44.75  ?  213 PHE B CA  1 
ATOM   6903  C  C   . PHE B 1 224 ? 132.518 156.049 149.240 1.00 44.75  ?  213 PHE B C   1 
ATOM   6904  O  O   . PHE B 1 224 ? 132.355 156.249 150.442 1.00 44.75  ?  213 PHE B O   1 
ATOM   6905  C  CB  . PHE B 1 224 ? 134.120 154.280 148.485 1.00 44.75  ?  213 PHE B CB  1 
ATOM   6906  C  CG  . PHE B 1 224 ? 134.998 154.571 149.657 1.00 44.75  ?  213 PHE B CG  1 
ATOM   6907  C  CD1 . PHE B 1 224 ? 135.076 153.690 150.711 1.00 44.75  ?  213 PHE B CD1 1 
ATOM   6908  C  CD2 . PHE B 1 224 ? 135.740 155.733 149.711 1.00 44.75  ?  213 PHE B CD2 1 
ATOM   6909  C  CE1 . PHE B 1 224 ? 135.871 153.963 151.788 1.00 44.75  ?  213 PHE B CE1 1 
ATOM   6910  C  CE2 . PHE B 1 224 ? 136.532 156.006 150.788 1.00 44.75  ?  213 PHE B CE2 1 
ATOM   6911  C  CZ  . PHE B 1 224 ? 136.601 155.119 151.826 1.00 44.75  ?  213 PHE B CZ  1 
ATOM   6912  N  N   . THR B 1 225 ? 132.569 157.048 148.362 1.00 46.04  ?  214 THR B N   1 
ATOM   6913  C  CA  . THR B 1 225 ? 132.492 158.420 148.841 1.00 46.04  ?  214 THR B CA  1 
ATOM   6914  C  C   . THR B 1 225 ? 131.077 158.811 149.234 1.00 46.04  ?  214 THR B C   1 
ATOM   6915  O  O   . THR B 1 225 ? 130.905 159.634 150.132 1.00 46.04  ?  214 THR B O   1 
ATOM   6916  C  CB  . THR B 1 225 ? 133.045 159.392 147.801 1.00 46.04  ?  214 THR B CB  1 
ATOM   6917  O  OG1 . THR B 1 225 ? 132.449 159.138 146.529 1.00 46.04  ?  214 THR B OG1 1 
ATOM   6918  C  CG2 . THR B 1 225 ? 134.538 159.238 147.688 1.00 46.04  ?  214 THR B CG2 1 
ATOM   6919  N  N   . THR B 1 226 ? 130.054 158.213 148.626 1.00 46.76  ?  215 THR B N   1 
ATOM   6920  C  CA  . THR B 1 226 ? 128.700 158.444 149.116 1.00 46.76  ?  215 THR B CA  1 
ATOM   6921  C  C   . THR B 1 226 ? 128.506 157.835 150.501 1.00 46.76  ?  215 THR B C   1 
ATOM   6922  O  O   . THR B 1 226 ? 127.946 158.474 151.404 1.00 46.76  ?  215 THR B O   1 
ATOM   6923  C  CB  . THR B 1 226 ? 127.682 157.884 148.127 1.00 46.76  ?  215 THR B CB  1 
ATOM   6924  O  OG1 . THR B 1 226 ? 128.157 158.088 146.796 1.00 46.76  ?  215 THR B OG1 1 
ATOM   6925  C  CG2 . THR B 1 226 ? 126.360 158.583 148.282 1.00 46.76  ?  215 THR B CG2 1 
ATOM   6926  N  N   . ALA B 1 227 ? 128.976 156.601 150.697 1.00 45.37  ?  216 ALA B N   1 
ATOM   6927  C  CA  . ALA B 1 227 ? 128.868 155.990 152.015 1.00 45.37  ?  216 ALA B CA  1 
ATOM   6928  C  C   . ALA B 1 227 ? 129.690 156.752 153.045 1.00 45.37  ?  216 ALA B C   1 
ATOM   6929  O  O   . ALA B 1 227 ? 129.285 156.884 154.204 1.00 45.37  ?  216 ALA B O   1 
ATOM   6930  C  CB  . ALA B 1 227 ? 129.297 154.530 151.946 1.00 45.37  ?  216 ALA B CB  1 
ATOM   6931  N  N   . ALA B 1 228 ? 130.834 157.291 152.632 1.00 46.26  ?  217 ALA B N   1 
ATOM   6932  C  CA  . ALA B 1 228 ? 131.662 158.072 153.536 1.00 46.26  ?  217 ALA B CA  1 
ATOM   6933  C  C   . ALA B 1 228 ? 131.026 159.411 153.870 1.00 46.26  ?  217 ALA B C   1 
ATOM   6934  O  O   . ALA B 1 228 ? 131.204 159.914 154.979 1.00 46.26  ?  217 ALA B O   1 
ATOM   6935  C  CB  . ALA B 1 228 ? 133.039 158.273 152.922 1.00 46.26  ?  217 ALA B CB  1 
ATOM   6936  N  N   . ALA B 1 229 ? 130.286 160.002 152.935 1.00 46.85  ?  218 ALA B N   1 
ATOM   6937  C  CA  . ALA B 1 229 ? 129.529 161.205 153.252 1.00 46.85  ?  218 ALA B CA  1 
ATOM   6938  C  C   . ALA B 1 229 ? 128.439 160.913 154.271 1.00 46.85  ?  218 ALA B C   1 
ATOM   6939  O  O   . ALA B 1 229 ? 128.173 161.733 155.152 1.00 46.85  ?  218 ALA B O   1 
ATOM   6940  C  CB  . ALA B 1 229 ? 128.931 161.799 151.982 1.00 46.85  ?  218 ALA B CB  1 
ATOM   6941  N  N   . VAL B 1 230 ? 127.791 159.754 154.164 1.00 46.26  ?  219 VAL B N   1 
ATOM   6942  C  CA  . VAL B 1 230 ? 126.814 159.372 155.182 1.00 46.26  ?  219 VAL B CA  1 
ATOM   6943  C  C   . VAL B 1 230 ? 127.495 159.188 156.536 1.00 46.26  ?  219 VAL B C   1 
ATOM   6944  O  O   . VAL B 1 230 ? 126.964 159.593 157.579 1.00 46.26  ?  219 VAL B O   1 
ATOM   6945  C  CB  . VAL B 1 230 ? 126.056 158.108 154.744 1.00 46.26  ?  219 VAL B CB  1 
ATOM   6946  C  CG1 . VAL B 1 230 ? 125.062 157.694 155.802 1.00 46.26  ?  219 VAL B CG1 1 
ATOM   6947  C  CG2 . VAL B 1 230 ? 125.349 158.354 153.439 1.00 46.26  ?  219 VAL B CG2 1 
ATOM   6948  N  N   . HIS B 1 231 ? 128.683 158.583 156.538 1.00 47.86  ?  220 HIS B N   1 
ATOM   6949  C  CA  . HIS B 1 231 ? 129.464 158.451 157.765 1.00 47.86  ?  220 HIS B CA  1 
ATOM   6950  C  C   . HIS B 1 231 ? 129.770 159.810 158.381 1.00 47.86  ?  220 HIS B C   1 
ATOM   6951  O  O   . HIS B 1 231 ? 129.648 159.994 159.595 1.00 47.86  ?  220 HIS B O   1 
ATOM   6952  C  CB  . HIS B 1 231 ? 130.767 157.714 157.476 1.00 47.86  ?  220 HIS B CB  1 
ATOM   6953  C  CG  . HIS B 1 231 ? 130.668 156.229 157.595 1.00 47.86  ?  220 HIS B CG  1 
ATOM   6954  N  ND1 . HIS B 1 231 ? 130.838 155.569 158.788 1.00 47.86  ?  220 HIS B ND1 1 
ATOM   6955  C  CD2 . HIS B 1 231 ? 130.436 155.277 156.666 1.00 47.86  ?  220 HIS B CD2 1 
ATOM   6956  C  CE1 . HIS B 1 231 ? 130.704 154.272 158.591 1.00 47.86  ?  220 HIS B CE1 1 
ATOM   6957  N  NE2 . HIS B 1 231 ? 130.460 154.068 157.311 1.00 47.86  ?  220 HIS B NE2 1 
ATOM   6958  N  N   . VAL B 1 232 ? 130.197 160.767 157.560 1.00 49.09  ?  221 VAL B N   1 
ATOM   6959  C  CA  . VAL B 1 232 ? 130.535 162.094 158.062 1.00 49.09  ?  221 VAL B CA  1 
ATOM   6960  C  C   . VAL B 1 232 ? 129.299 162.787 158.614 1.00 49.09  ?  221 VAL B C   1 
ATOM   6961  O  O   . VAL B 1 232 ? 129.347 163.431 159.669 1.00 49.09  ?  221 VAL B O   1 
ATOM   6962  C  CB  . VAL B 1 232 ? 131.203 162.929 156.954 1.00 49.09  ?  221 VAL B CB  1 
ATOM   6963  C  CG1 . VAL B 1 232 ? 131.272 164.382 157.352 1.00 49.09  ?  221 VAL B CG1 1 
ATOM   6964  C  CG2 . VAL B 1 232 ? 132.583 162.406 156.650 1.00 49.09  ?  221 VAL B CG2 1 
ATOM   6965  N  N   . LEU B 1 233 ? 128.177 162.678 157.904 1.00 50.53  ?  222 LEU B N   1 
ATOM   6966  C  CA  . LEU B 1 233 ? 126.924 163.239 158.390 1.00 50.53  ?  222 LEU B CA  1 
ATOM   6967  C  C   . LEU B 1 233 ? 126.588 162.706 159.772 1.00 50.53  ?  222 LEU B C   1 
ATOM   6968  O  O   . LEU B 1 233 ? 126.242 163.471 160.675 1.00 50.53  ?  222 LEU B O   1 
ATOM   6969  C  CB  . LEU B 1 233 ? 125.803 162.918 157.405 1.00 50.53  ?  222 LEU B CB  1 
ATOM   6970  C  CG  . LEU B 1 233 ? 124.569 163.811 157.344 1.00 50.53  ?  222 LEU B CG  1 
ATOM   6971  C  CD1 . LEU B 1 233 ? 123.817 163.516 156.077 1.00 50.53  ?  222 LEU B CD1 1 
ATOM   6972  C  CD2 . LEU B 1 233 ? 123.674 163.599 158.534 1.00 50.53  ?  222 LEU B CD2 1 
ATOM   6973  N  N   . VAL B 1 234 ? 126.672 161.389 159.953 1.00 51.59  ?  223 VAL B N   1 
ATOM   6974  C  CA  . VAL B 1 234 ? 126.351 160.823 161.256 1.00 51.59  ?  223 VAL B CA  1 
ATOM   6975  C  C   . VAL B 1 234 ? 127.368 161.261 162.299 1.00 51.59  ?  223 VAL B C   1 
ATOM   6976  O  O   . VAL B 1 234 ? 127.022 161.463 163.466 1.00 51.59  ?  223 VAL B O   1 
ATOM   6977  C  CB  . VAL B 1 234 ? 126.248 159.292 161.153 1.00 51.59  ?  223 VAL B CB  1 
ATOM   6978  C  CG1 . VAL B 1 234 ? 126.188 158.664 162.522 1.00 51.59  ?  223 VAL B CG1 1 
ATOM   6979  C  CG2 . VAL B 1 234 ? 125.027 158.913 160.358 1.00 51.59  ?  223 VAL B CG2 1 
ATOM   6980  N  N   . SER B 1 235 ? 128.622 161.448 161.903 1.00 53.64  ?  224 SER B N   1 
ATOM   6981  C  CA  . SER B 1 235 ? 129.653 161.886 162.831 1.00 53.64  ?  224 SER B CA  1 
ATOM   6982  C  C   . SER B 1 235 ? 129.450 163.303 163.332 1.00 53.64  ?  224 SER B C   1 
ATOM   6983  O  O   . SER B 1 235 ? 129.934 163.631 164.415 1.00 53.64  ?  224 SER B O   1 
ATOM   6984  C  CB  . SER B 1 235 ? 131.020 161.787 162.172 1.00 53.64  ?  224 SER B CB  1 
ATOM   6985  O  OG  . SER B 1 235 ? 131.454 160.450 162.142 1.00 53.64  ?  224 SER B OG  1 
ATOM   6986  N  N   . GLN B 1 236 ? 128.770 164.150 162.573 1.00 54.30  ?  225 GLN B N   1 
ATOM   6987  C  CA  . GLN B 1 236 ? 128.556 165.522 163.006 1.00 54.30  ?  225 GLN B CA  1 
ATOM   6988  C  C   . GLN B 1 236 ? 127.381 165.684 163.955 1.00 54.30  ?  225 GLN B C   1 
ATOM   6989  O  O   . GLN B 1 236 ? 127.211 166.768 164.517 1.00 54.30  ?  225 GLN B O   1 
ATOM   6990  C  CB  . GLN B 1 236 ? 128.344 166.436 161.801 1.00 54.30  ?  225 GLN B CB  1 
ATOM   6991  C  CG  . GLN B 1 236 ? 129.415 166.339 160.750 1.00 54.30  ?  225 GLN B CG  1 
ATOM   6992  C  CD  . GLN B 1 236 ? 130.729 166.913 161.193 1.00 54.30  ?  225 GLN B CD  1 
ATOM   6993  O  OE1 . GLN B 1 236 ? 130.870 167.393 162.310 1.00 54.30  ?  225 GLN B OE1 1 
ATOM   6994  N  NE2 . GLN B 1 236 ? 131.707 166.868 160.314 1.00 54.30  ?  225 GLN B NE2 1 
ATOM   6995  N  N   . LEU B 1 237 ? 126.579 164.642 164.156 1.00 54.54  ?  226 LEU B N   1 
ATOM   6996  C  CA  . LEU B 1 237 ? 125.354 164.787 164.932 1.00 54.54  ?  226 LEU B CA  1 
ATOM   6997  C  C   . LEU B 1 237 ? 125.634 165.029 166.404 1.00 54.54  ?  226 LEU B C   1 
ATOM   6998  O  O   . LEU B 1 237 ? 124.875 165.741 167.062 1.00 54.54  ?  226 LEU B O   1 
ATOM   6999  C  CB  . LEU B 1 237 ? 124.481 163.552 164.760 1.00 54.54  ?  226 LEU B CB  1 
ATOM   7000  C  CG  . LEU B 1 237 ? 123.937 163.331 163.354 1.00 54.54  ?  226 LEU B CG  1 
ATOM   7001  C  CD1 . LEU B 1 237 ? 122.999 162.155 163.348 1.00 54.54  ?  226 LEU B CD1 1 
ATOM   7002  C  CD2 . LEU B 1 237 ? 123.250 164.580 162.846 1.00 54.54  ?  226 LEU B CD2 1 
ATOM   7003  N  N   . LYS B 1 238 ? 126.707 164.454 166.941 1.00 56.23  ?  227 LYS B N   1 
ATOM   7004  C  CA  . LYS B 1 238 ? 127.037 164.689 168.338 1.00 56.23  ?  227 LYS B CA  1 
ATOM   7005  C  C   . LYS B 1 238 ? 127.449 166.127 168.602 1.00 56.23  ?  227 LYS B C   1 
ATOM   7006  O  O   . LYS B 1 238 ? 127.424 166.554 169.756 1.00 56.23  ?  227 LYS B O   1 
ATOM   7007  C  CB  . LYS B 1 238 ? 128.150 163.748 168.787 1.00 56.23  ?  227 LYS B CB  1 
ATOM   7008  C  CG  . LYS B 1 238 ? 129.432 163.922 168.031 1.00 56.23  ?  227 LYS B CG  1 
ATOM   7009  C  CD  . LYS B 1 238 ? 130.423 162.840 168.360 1.00 56.23  ?  227 LYS B CD  1 
ATOM   7010  C  CE  . LYS B 1 238 ? 130.990 163.034 169.740 1.00 56.23  ?  227 LYS B CE  1 
ATOM   7011  N  NZ  . LYS B 1 238 ? 132.000 161.995 170.066 1.00 56.23  1  227 LYS B NZ  1 
ATOM   7012  N  N   . PHE B 1 239 ? 127.831 166.878 167.575 1.00 54.36  ?  228 PHE B N   1 
ATOM   7013  C  CA  . PHE B 1 239 ? 128.152 168.289 167.739 1.00 54.36  ?  228 PHE B CA  1 
ATOM   7014  C  C   . PHE B 1 239 ? 126.985 169.194 167.396 1.00 54.36  ?  228 PHE B C   1 
ATOM   7015  O  O   . PHE B 1 239 ? 126.842 170.257 168.001 1.00 54.36  ?  228 PHE B O   1 
ATOM   7016  C  CB  . PHE B 1 239 ? 129.355 168.666 166.878 1.00 54.36  ?  228 PHE B CB  1 
ATOM   7017  C  CG  . PHE B 1 239 ? 130.560 167.838 167.149 1.00 54.36  ?  228 PHE B CG  1 
ATOM   7018  C  CD1 . PHE B 1 239 ? 131.270 167.996 168.316 1.00 54.36  ?  228 PHE B CD1 1 
ATOM   7019  C  CD2 . PHE B 1 239 ? 130.974 166.886 166.245 1.00 54.36  ?  228 PHE B CD2 1 
ATOM   7020  C  CE1 . PHE B 1 239 ? 132.371 167.230 168.570 1.00 54.36  ?  228 PHE B CE1 1 
ATOM   7021  C  CE2 . PHE B 1 239 ? 132.073 166.119 166.497 1.00 54.36  ?  228 PHE B CE2 1 
ATOM   7022  C  CZ  . PHE B 1 239 ? 132.772 166.290 167.661 1.00 54.36  ?  228 PHE B CZ  1 
ATOM   7023  N  N   . ILE B 1 240 ? 126.150 168.796 166.439 1.00 56.74  ?  229 ILE B N   1 
ATOM   7024  C  CA  . ILE B 1 240 ? 124.939 169.558 166.159 1.00 56.74  ?  229 ILE B CA  1 
ATOM   7025  C  C   . ILE B 1 240 ? 124.024 169.573 167.375 1.00 56.74  ?  229 ILE B C   1 
ATOM   7026  O  O   . ILE B 1 240 ? 123.444 170.607 167.714 1.00 56.74  ?  229 ILE B O   1 
ATOM   7027  C  CB  . ILE B 1 240 ? 124.222 168.981 164.928 1.00 56.74  ?  229 ILE B CB  1 
ATOM   7028  C  CG1 . ILE B 1 240 ? 125.130 169.039 163.707 1.00 56.74  ?  229 ILE B CG1 1 
ATOM   7029  C  CG2 . ILE B 1 240 ? 122.944 169.727 164.659 1.00 56.74  ?  229 ILE B CG2 1 
ATOM   7030  C  CD1 . ILE B 1 240 ? 125.708 170.376 163.463 1.00 56.74  ?  229 ILE B CD1 1 
ATOM   7031  N  N   . PHE B 1 241 ? 123.880 168.433 168.050 1.00 58.50  ?  230 PHE B N   1 
ATOM   7032  C  CA  . PHE B 1 241 ? 123.038 168.316 169.228 1.00 58.50  ?  230 PHE B CA  1 
ATOM   7033  C  C   . PHE B 1 241 ? 123.791 168.508 170.533 1.00 58.50  ?  230 PHE B C   1 
ATOM   7034  O  O   . PHE B 1 241 ? 123.154 168.690 171.571 1.00 58.50  ?  230 PHE B O   1 
ATOM   7035  C  CB  . PHE B 1 241 ? 122.355 166.943 169.258 1.00 58.50  ?  230 PHE B CB  1 
ATOM   7036  C  CG  . PHE B 1 241 ? 121.571 166.625 168.024 1.00 58.50  ?  230 PHE B CG  1 
ATOM   7037  C  CD1 . PHE B 1 241 ? 120.680 167.534 167.502 1.00 58.50  ?  230 PHE B CD1 1 
ATOM   7038  C  CD2 . PHE B 1 241 ? 121.720 165.411 167.391 1.00 58.50  ?  230 PHE B CD2 1 
ATOM   7039  C  CE1 . PHE B 1 241 ? 119.967 167.242 166.376 1.00 58.50  ?  230 PHE B CE1 1 
ATOM   7040  C  CE2 . PHE B 1 241 ? 121.005 165.119 166.264 1.00 58.50  ?  230 PHE B CE2 1 
ATOM   7041  C  CZ  . PHE B 1 241 ? 120.130 166.034 165.757 1.00 58.50  ?  230 PHE B CZ  1 
ATOM   7042  N  N   . GLN B 1 242 ? 125.120 168.472 170.502 1.00 60.29  ?  231 GLN B N   1 
ATOM   7043  C  CA  . GLN B 1 242 ? 125.964 168.517 171.694 1.00 60.29  ?  231 GLN B CA  1 
ATOM   7044  C  C   . GLN B 1 242 ? 125.671 167.358 172.638 1.00 60.29  ?  231 GLN B C   1 
ATOM   7045  O  O   . GLN B 1 242 ? 125.326 167.552 173.802 1.00 60.29  ?  231 GLN B O   1 
ATOM   7046  C  CB  . GLN B 1 242 ? 125.843 169.852 172.424 1.00 60.29  ?  231 GLN B CB  1 
ATOM   7047  C  CG  . GLN B 1 242 ? 127.070 170.183 173.226 1.00 60.29  ?  231 GLN B CG  1 
ATOM   7048  C  CD  . GLN B 1 242 ? 126.772 171.061 174.399 1.00 60.29  ?  231 GLN B CD  1 
ATOM   7049  O  OE1 . GLN B 1 242 ? 126.008 172.010 174.295 1.00 60.29  ?  231 GLN B OE1 1 
ATOM   7050  N  NE2 . GLN B 1 242 ? 127.370 170.748 175.535 1.00 60.29  ?  231 GLN B NE2 1 
ATOM   7051  N  N   . LEU B 1 243 ? 125.822 166.145 172.132 1.00 59.13  ?  232 LEU B N   1 
ATOM   7052  C  CA  . LEU B 1 243 ? 125.621 164.939 172.911 1.00 59.13  ?  232 LEU B CA  1 
ATOM   7053  C  C   . LEU B 1 243 ? 126.947 164.225 173.117 1.00 59.13  ?  232 LEU B C   1 
ATOM   7054  O  O   . LEU B 1 243 ? 127.881 164.372 172.329 1.00 59.13  ?  232 LEU B O   1 
ATOM   7055  C  CB  . LEU B 1 243 ? 124.630 164.009 172.216 1.00 59.13  ?  232 LEU B CB  1 
ATOM   7056  C  CG  . LEU B 1 243 ? 123.230 164.574 172.002 1.00 59.13  ?  232 LEU B CG  1 
ATOM   7057  C  CD1 . LEU B 1 243 ? 122.441 163.666 171.106 1.00 59.13  ?  232 LEU B CD1 1 
ATOM   7058  C  CD2 . LEU B 1 243 ? 122.523 164.758 173.321 1.00 59.13  ?  232 LEU B CD2 1 
ATOM   7059  N  N   . THR B 1 244 ? 127.024 163.449 174.190 1.00 59.49  ?  233 THR B N   1 
ATOM   7060  C  CA  . THR B 1 244 ? 128.209 162.661 174.494 1.00 59.49  ?  233 THR B CA  1 
ATOM   7061  C  C   . THR B 1 244 ? 128.017 161.263 173.926 1.00 59.49  ?  233 THR B C   1 
ATOM   7062  O  O   . THR B 1 244 ? 127.079 160.557 174.304 1.00 59.49  ?  233 THR B O   1 
ATOM   7063  C  CB  . THR B 1 244 ? 128.459 162.604 175.996 1.00 59.49  ?  233 THR B CB  1 
ATOM   7064  O  OG1 . THR B 1 244 ? 128.419 163.927 176.533 1.00 59.49  ?  233 THR B OG1 1 
ATOM   7065  C  CG2 . THR B 1 244 ? 129.815 161.994 176.279 1.00 59.49  ?  233 THR B CG2 1 
ATOM   7066  N  N   . VAL B 1 245 ? 128.899 160.868 173.022 1.00 56.65  ?  234 VAL B N   1 
ATOM   7067  C  CA  . VAL B 1 245 ? 128.778 159.612 172.290 1.00 56.65  ?  234 VAL B CA  1 
ATOM   7068  C  C   . VAL B 1 245 ? 130.030 158.787 172.553 1.00 56.65  ?  234 VAL B C   1 
ATOM   7069  O  O   . VAL B 1 245 ? 131.136 159.334 172.522 1.00 56.65  ?  234 VAL B O   1 
ATOM   7070  C  CB  . VAL B 1 245 ? 128.574 159.862 170.786 1.00 56.65  ?  234 VAL B CB  1 
ATOM   7071  C  CG1 . VAL B 1 245 ? 128.731 158.590 169.993 1.00 56.65  ?  234 VAL B CG1 1 
ATOM   7072  C  CG2 . VAL B 1 245 ? 127.213 160.466 170.546 1.00 56.65  ?  234 VAL B CG2 1 
ATOM   7073  N  N   . PRO B 1 246 ? 129.906 157.496 172.844 1.00 57.02  ?  235 PRO B N   1 
ATOM   7074  C  CA  . PRO B 1 246 ? 131.094 156.672 173.075 1.00 57.02  ?  235 PRO B CA  1 
ATOM   7075  C  C   . PRO B 1 246 ? 131.947 156.540 171.824 1.00 57.02  ?  235 PRO B C   1 
ATOM   7076  O  O   . PRO B 1 246 ? 131.539 156.873 170.712 1.00 57.02  ?  235 PRO B O   1 
ATOM   7077  C  CB  . PRO B 1 246 ? 130.513 155.319 173.489 1.00 57.02  ?  235 PRO B CB  1 
ATOM   7078  C  CG  . PRO B 1 246 ? 129.157 155.619 173.959 1.00 57.02  ?  235 PRO B CG  1 
ATOM   7079  C  CD  . PRO B 1 246 ? 128.669 156.770 173.156 1.00 57.02  ?  235 PRO B CD  1 
ATOM   7080  N  N   . SER B 1 247 ? 133.141 155.985 171.988 1.00 58.30  ?  236 SER B N   1 
ATOM   7081  C  CA  . SER B 1 247 ? 134.025 155.769 170.850 1.00 58.30  ?  236 SER B CA  1 
ATOM   7082  C  C   . SER B 1 247 ? 133.759 154.419 170.210 1.00 58.30  ?  236 SER B C   1 
ATOM   7083  O  O   . SER B 1 247 ? 134.529 153.483 170.400 1.00 58.30  ?  236 SER B O   1 
ATOM   7084  C  CB  . SER B 1 247 ? 135.482 155.846 171.300 1.00 58.30  ?  236 SER B CB  1 
ATOM   7085  O  OG  . SER B 1 247 ? 135.789 157.127 171.816 1.00 58.30  ?  236 SER B OG  1 
ATOM   7086  N  N   . HIS B 1 248 ? 132.691 154.317 169.421 1.00 56.75  ?  237 HIS B N   1 
ATOM   7087  C  CA  . HIS B 1 248 ? 132.301 153.069 168.758 1.00 56.75  ?  237 HIS B CA  1 
ATOM   7088  C  C   . HIS B 1 248 ? 133.255 152.679 167.639 1.00 56.75  ?  237 HIS B C   1 
ATOM   7089  O  O   . HIS B 1 248 ? 133.823 153.529 166.979 1.00 56.75  ?  237 HIS B O   1 
ATOM   7090  C  CB  . HIS B 1 248 ? 130.888 153.180 168.180 1.00 56.75  ?  237 HIS B CB  1 
ATOM   7091  C  CG  . HIS B 1 248 ? 129.852 153.633 169.157 1.00 56.75  ?  237 HIS B CG  1 
ATOM   7092  N  ND1 . HIS B 1 248 ? 129.345 152.820 170.143 1.00 56.75  ?  237 HIS B ND1 1 
ATOM   7093  C  CD2 . HIS B 1 248 ? 129.197 154.813 169.274 1.00 56.75  ?  237 HIS B CD2 1 
ATOM   7094  C  CE1 . HIS B 1 248 ? 128.431 153.480 170.832 1.00 56.75  ?  237 HIS B CE1 1 
ATOM   7095  N  NE2 . HIS B 1 248 ? 128.328 154.691 170.318 1.00 56.75  ?  237 HIS B NE2 1 
ATOM   7096  N  N   . THR B 1 249 ? 133.479 151.392 167.452 1.00 59.43  ?  238 THR B N   1 
ATOM   7097  C  CA  . THR B 1 249 ? 134.368 150.959 166.392 1.00 59.43  ?  238 THR B CA  1 
ATOM   7098  C  C   . THR B 1 249 ? 133.596 150.127 165.391 1.00 59.43  ?  238 THR B C   1 
ATOM   7099  O  O   . THR B 1 249 ? 132.411 149.905 165.551 1.00 59.43  ?  238 THR B O   1 
ATOM   7100  C  CB  . THR B 1 249 ? 135.561 150.152 166.925 1.00 59.43  ?  238 THR B CB  1 
ATOM   7101  O  OG1 . THR B 1 249 ? 135.092 149.135 167.814 1.00 59.43  ?  238 THR B OG1 1 
ATOM   7102  C  CG2 . THR B 1 249 ? 136.524 151.052 167.665 1.00 59.43  ?  238 THR B CG2 1 
ATOM   7103  N  N   . ASP B 1 250 ? 134.285 149.654 164.369 1.00 59.04  ?  239 ASP B N   1 
ATOM   7104  C  CA  . ASP B 1 250 ? 133.660 148.866 163.327 1.00 59.04  ?  239 ASP B CA  1 
ATOM   7105  C  C   . ASP B 1 250 ? 133.763 147.376 163.570 1.00 59.04  ?  239 ASP B C   1 
ATOM   7106  O  O   . ASP B 1 250 ? 134.700 146.925 164.212 1.00 59.04  ?  239 ASP B O   1 
ATOM   7107  C  CB  . ASP B 1 250 ? 134.276 149.246 161.995 1.00 59.04  ?  239 ASP B CB  1 
ATOM   7108  C  CG  . ASP B 1 250 ? 133.639 150.471 161.410 1.00 59.04  ?  239 ASP B CG  1 
ATOM   7109  O  OD1 . ASP B 1 250 ? 134.360 151.438 161.122 1.00 59.04  ?  239 ASP B OD1 1 
ATOM   7110  O  OD2 . ASP B 1 250 ? 132.415 150.470 161.215 1.00 59.04  -1 239 ASP B OD2 1 
ATOM   7111  N  N   . PRO B 1 251 ? 132.788 146.597 163.074 1.00 59.13  ?  240 PRO B N   1 
ATOM   7112  C  CA  . PRO B 1 251 ? 131.834 146.897 162.008 1.00 59.13  ?  240 PRO B CA  1 
ATOM   7113  C  C   . PRO B 1 251 ? 130.608 147.595 162.535 1.00 59.13  ?  240 PRO B C   1 
ATOM   7114  O  O   . PRO B 1 251 ? 130.472 147.725 163.731 1.00 59.13  ?  240 PRO B O   1 
ATOM   7115  C  CB  . PRO B 1 251 ? 131.461 145.516 161.491 1.00 59.13  ?  240 PRO B CB  1 
ATOM   7116  C  CG  . PRO B 1 251 ? 131.550 144.650 162.690 1.00 59.13  ?  240 PRO B CG  1 
ATOM   7117  C  CD  . PRO B 1 251 ? 132.631 145.217 163.562 1.00 59.13  ?  240 PRO B CD  1 
ATOM   7118  N  N   . VAL B 1 252 ? 129.807 148.138 161.633 1.00 54.80  ?  241 VAL B N   1 
ATOM   7119  C  CA  . VAL B 1 252 ? 128.542 148.818 161.921 1.00 54.80  ?  241 VAL B CA  1 
ATOM   7120  C  C   . VAL B 1 252 ? 128.619 149.946 162.934 1.00 54.80  ?  241 VAL B C   1 
ATOM   7121  O  O   . VAL B 1 252 ? 127.680 150.182 163.666 1.00 54.80  ?  241 VAL B O   1 
ATOM   7122  C  CB  . VAL B 1 252 ? 127.345 147.857 162.178 1.00 54.80  ?  241 VAL B CB  1 
ATOM   7123  C  CG1 . VAL B 1 252 ? 127.364 146.704 161.199 1.00 54.80  ?  241 VAL B CG1 1 
ATOM   7124  C  CG2 . VAL B 1 252 ? 127.288 147.353 163.609 1.00 54.80  ?  241 VAL B CG2 1 
ATOM   7125  N  N   . SER B 1 253 ? 129.720 150.685 162.910 1.00 55.06  ?  242 SER B N   1 
ATOM   7126  C  CA  . SER B 1 253 ? 129.944 151.819 163.782 1.00 55.06  ?  242 SER B CA  1 
ATOM   7127  C  C   . SER B 1 253 ? 128.951 152.921 163.492 1.00 55.06  ?  242 SER B C   1 
ATOM   7128  O  O   . SER B 1 253 ? 128.536 153.609 164.389 1.00 55.06  ?  242 SER B O   1 
ATOM   7129  C  CB  . SER B 1 253 ? 131.378 152.329 163.710 1.00 55.06  ?  242 SER B CB  1 
ATOM   7130  O  OG  . SER B 1 253 ? 131.616 153.040 162.528 1.00 55.06  ?  242 SER B OG  1 
ATOM   7131  N  N   . ILE B 1 254 ? 128.577 153.102 162.234 1.00 52.08  ?  243 ILE B N   1 
ATOM   7132  C  CA  . ILE B 1 254 ? 127.629 154.141 161.883 1.00 52.08  ?  243 ILE B CA  1 
ATOM   7133  C  C   . ILE B 1 254 ? 126.287 153.926 162.595 1.00 52.08  ?  243 ILE B C   1 
ATOM   7134  O  O   . ILE B 1 254 ? 125.680 154.878 163.043 1.00 52.08  ?  243 ILE B O   1 
ATOM   7135  C  CB  . ILE B 1 254 ? 127.511 154.301 160.339 1.00 52.08  ?  243 ILE B CB  1 
ATOM   7136  C  CG1 . ILE B 1 254 ? 126.721 155.548 159.960 1.00 52.08  ?  243 ILE B CG1 1 
ATOM   7137  C  CG2 . ILE B 1 254 ? 126.938 153.064 159.658 1.00 52.08  ?  243 ILE B CG2 1 
ATOM   7138  C  CD1 . ILE B 1 254 ? 126.751 155.833 158.482 1.00 52.08  ?  243 ILE B CD1 1 
ATOM   7139  N  N   . PHE B 1 255 ? 125.821 152.686 162.673 1.00 53.58  ?  244 PHE B N   1 
ATOM   7140  C  CA  . PHE B 1 255 ? 124.595 152.336 163.378 1.00 53.58  ?  244 PHE B CA  1 
ATOM   7141  C  C   . PHE B 1 255 ? 124.695 152.490 164.886 1.00 53.58  ?  244 PHE B C   1 
ATOM   7142  O  O   . PHE B 1 255 ? 123.749 152.893 165.526 1.00 53.58  ?  244 PHE B O   1 
ATOM   7143  C  CB  . PHE B 1 255 ? 124.126 150.940 162.992 1.00 53.58  ?  244 PHE B CB  1 
ATOM   7144  C  CG  . PHE B 1 255 ? 123.797 150.811 161.546 1.00 53.58  ?  244 PHE B CG  1 
ATOM   7145  C  CD1 . PHE B 1 255 ? 122.732 151.496 161.014 1.00 53.58  ?  244 PHE B CD1 1 
ATOM   7146  C  CD2 . PHE B 1 255 ? 124.560 150.028 160.714 1.00 53.58  ?  244 PHE B CD2 1 
ATOM   7147  C  CE1 . PHE B 1 255 ? 122.422 151.393 159.678 1.00 53.58  ?  244 PHE B CE1 1 
ATOM   7148  C  CE2 . PHE B 1 255 ? 124.257 149.923 159.377 1.00 53.58  ?  244 PHE B CE2 1 
ATOM   7149  C  CZ  . PHE B 1 255 ? 123.185 150.604 158.858 1.00 53.58  ?  244 PHE B CZ  1 
ATOM   7150  N  N   . LYS B 1 256 ? 125.843 152.123 165.441 1.00 53.93  ?  245 LYS B N   1 
ATOM   7151  C  CA  . LYS B 1 256 ? 126.100 152.221 166.869 1.00 53.93  ?  245 LYS B CA  1 
ATOM   7152  C  C   . LYS B 1 256 ? 125.981 153.649 167.363 1.00 53.93  ?  245 LYS B C   1 
ATOM   7153  O  O   . LYS B 1 256 ? 125.393 153.907 168.396 1.00 53.93  ?  245 LYS B O   1 
ATOM   7154  C  CB  . LYS B 1 256 ? 127.484 151.700 167.181 1.00 53.93  ?  245 LYS B CB  1 
ATOM   7155  C  CG  . LYS B 1 256 ? 127.680 150.225 166.934 1.00 53.93  ?  245 LYS B CG  1 
ATOM   7156  C  CD  . LYS B 1 256 ? 129.121 149.869 167.211 1.00 53.93  ?  245 LYS B CD  1 
ATOM   7157  C  CE  . LYS B 1 256 ? 129.423 148.443 166.834 1.00 53.93  ?  245 LYS B CE  1 
ATOM   7158  N  NZ  . LYS B 1 256 ? 130.866 148.157 167.013 1.00 53.93  1  245 LYS B NZ  1 
ATOM   7159  N  N   . VAL B 1 257 ? 126.591 154.560 166.628 1.00 53.89  ?  246 VAL B N   1 
ATOM   7160  C  CA  . VAL B 1 257 ? 126.570 155.995 166.896 1.00 53.89  ?  246 VAL B CA  1 
ATOM   7161  C  C   . VAL B 1 257 ? 125.177 156.594 166.783 1.00 53.89  ?  246 VAL B C   1 
ATOM   7162  O  O   . VAL B 1 257 ? 124.784 157.406 167.613 1.00 53.89  ?  246 VAL B O   1 
ATOM   7163  C  CB  . VAL B 1 257 ? 127.520 156.751 165.942 1.00 53.89  ?  246 VAL B CB  1 
ATOM   7164  C  CG1 . VAL B 1 257 ? 127.417 158.251 166.160 1.00 53.89  ?  246 VAL B CG1 1 
ATOM   7165  C  CG2 . VAL B 1 257 ? 128.948 156.271 166.129 1.00 53.89  ?  246 VAL B CG2 1 
ATOM   7166  N  N   . LEU B 1 258 ? 124.431 156.203 165.760 1.00 54.77  ?  247 LEU B N   1 
ATOM   7167  C  CA  . LEU B 1 258 ? 123.086 156.727 165.570 1.00 54.77  ?  247 LEU B CA  1 
ATOM   7168  C  C   . LEU B 1 258 ? 122.204 156.354 166.739 1.00 54.77  ?  247 LEU B C   1 
ATOM   7169  O  O   . LEU B 1 258 ? 121.385 157.153 167.181 1.00 54.77  ?  247 LEU B O   1 
ATOM   7170  C  CB  . LEU B 1 258 ? 122.488 156.204 164.272 1.00 54.77  ?  247 LEU B CB  1 
ATOM   7171  C  CG  . LEU B 1 258 ? 122.973 156.843 162.976 1.00 54.77  ?  247 LEU B CG  1 
ATOM   7172  C  CD1 . LEU B 1 258 ? 122.465 156.054 161.781 1.00 54.77  ?  247 LEU B CD1 1 
ATOM   7173  C  CD2 . LEU B 1 258 ? 122.500 158.286 162.913 1.00 54.77  ?  247 LEU B CD2 1 
ATOM   7174  N  N   . TYR B 1 259 ? 122.364 155.142 167.246 1.00 57.46  ?  248 TYR B N   1 
ATOM   7175  C  CA  . TYR B 1 259 ? 121.611 154.738 168.413 1.00 57.46  ?  248 TYR B CA  1 
ATOM   7176  C  C   . TYR B 1 259 ? 121.981 155.603 169.594 1.00 57.46  ?  248 TYR B C   1 
ATOM   7177  O  O   . TYR B 1 259 ? 121.110 156.088 170.305 1.00 57.46  ?  248 TYR B O   1 
ATOM   7178  C  CB  . TYR B 1 259 ? 121.891 153.285 168.755 1.00 57.46  ?  248 TYR B CB  1 
ATOM   7179  C  CG  . TYR B 1 259 ? 121.276 152.877 170.069 1.00 57.46  ?  248 TYR B CG  1 
ATOM   7180  C  CD1 . TYR B 1 259 ? 122.055 152.725 171.205 1.00 57.46  ?  248 TYR B CD1 1 
ATOM   7181  C  CD2 . TYR B 1 259 ? 119.909 152.675 170.179 1.00 57.46  ?  248 TYR B CD2 1 
ATOM   7182  C  CE1 . TYR B 1 259 ? 121.492 152.364 172.412 1.00 57.46  ?  248 TYR B CE1 1 
ATOM   7183  C  CE2 . TYR B 1 259 ? 119.338 152.314 171.382 1.00 57.46  ?  248 TYR B CE2 1 
ATOM   7184  C  CZ  . TYR B 1 259 ? 120.134 152.160 172.493 1.00 57.46  ?  248 TYR B CZ  1 
ATOM   7185  O  OH  . TYR B 1 259 ? 119.568 151.801 173.693 1.00 57.46  ?  248 TYR B OH  1 
ATOM   7186  N  N   . SER B 1 260 ? 123.275 155.800 169.803 1.00 57.87  ?  249 SER B N   1 
ATOM   7187  C  CA  . SER B 1 260 ? 123.742 156.618 170.911 1.00 57.87  ?  249 SER B CA  1 
ATOM   7188  C  C   . SER B 1 260 ? 123.244 158.051 170.805 1.00 57.87  ?  249 SER B C   1 
ATOM   7189  O  O   . SER B 1 260 ? 122.918 158.668 171.808 1.00 57.87  ?  249 SER B O   1 
ATOM   7190  C  CB  . SER B 1 260 ? 125.267 156.601 170.969 1.00 57.87  ?  249 SER B CB  1 
ATOM   7191  O  OG  . SER B 1 260 ? 125.763 155.276 170.987 1.00 57.87  ?  249 SER B OG  1 
ATOM   7192  N  N   . VAL B 1 261 ? 123.189 158.584 169.593 1.00 57.84  ?  250 VAL B N   1 
ATOM   7193  C  CA  . VAL B 1 261 ? 122.743 159.959 169.400 1.00 57.84  ?  250 VAL B CA  1 
ATOM   7194  C  C   . VAL B 1 261 ? 121.267 160.147 169.687 1.00 57.84  ?  250 VAL B C   1 
ATOM   7195  O  O   . VAL B 1 261 ? 120.890 161.067 170.404 1.00 57.84  ?  250 VAL B O   1 
ATOM   7196  C  CB  . VAL B 1 261 ? 123.023 160.442 167.960 1.00 57.84  ?  250 VAL B CB  1 
ATOM   7197  C  CG1 . VAL B 1 261 ? 122.235 161.706 167.654 1.00 57.84  ?  250 VAL B CG1 1 
ATOM   7198  C  CG2 . VAL B 1 261 ? 124.512 160.666 167.756 1.00 57.84  ?  250 VAL B CG2 1 
ATOM   7199  N  N   . PHE B 1 262 ? 120.427 159.275 169.150 1.00 59.90  ?  251 PHE B N   1 
ATOM   7200  C  CA  . PHE B 1 262 ? 118.982 159.457 169.304 1.00 59.90  ?  251 PHE B CA  1 
ATOM   7201  C  C   . PHE B 1 262 ? 118.455 158.870 170.596 1.00 59.90  ?  251 PHE B C   1 
ATOM   7202  O  O   . PHE B 1 262 ? 117.347 159.194 171.012 1.00 59.90  ?  251 PHE B O   1 
ATOM   7203  C  CB  . PHE B 1 262 ? 118.262 158.897 168.082 1.00 59.90  ?  251 PHE B CB  1 
ATOM   7204  C  CG  . PHE B 1 262 ? 118.624 159.607 166.814 1.00 59.90  ?  251 PHE B CG  1 
ATOM   7205  C  CD1 . PHE B 1 262 ? 118.123 160.868 166.550 1.00 59.90  ?  251 PHE B CD1 1 
ATOM   7206  C  CD2 . PHE B 1 262 ? 119.491 159.032 165.904 1.00 59.90  ?  251 PHE B CD2 1 
ATOM   7207  C  CE1 . PHE B 1 262 ? 118.464 161.536 165.393 1.00 59.90  ?  251 PHE B CE1 1 
ATOM   7208  C  CE2 . PHE B 1 262 ? 119.837 159.694 164.744 1.00 59.90  ?  251 PHE B CE2 1 
ATOM   7209  C  CZ  . PHE B 1 262 ? 119.323 160.948 164.487 1.00 59.90  ?  251 PHE B CZ  1 
ATOM   7210  N  N   . SER B 1 263 ? 119.240 158.022 171.242 1.00 60.57  ?  252 SER B N   1 
ATOM   7211  C  CA  . SER B 1 263 ? 118.844 157.514 172.538 1.00 60.57  ?  252 SER B CA  1 
ATOM   7212  C  C   . SER B 1 263 ? 118.881 158.661 173.531 1.00 60.57  ?  252 SER B C   1 
ATOM   7213  O  O   . SER B 1 263 ? 118.114 158.675 174.490 1.00 60.57  ?  252 SER B O   1 
ATOM   7214  C  CB  . SER B 1 263 ? 119.787 156.404 172.977 1.00 60.57  ?  252 SER B CB  1 
ATOM   7215  O  OG  . SER B 1 263 ? 119.483 155.964 174.287 1.00 60.57  ?  252 SER B OG  1 
ATOM   7216  N  N   . GLN B 1 264 ? 119.769 159.629 173.311 1.00 60.81  ?  253 GLN B N   1 
ATOM   7217  C  CA  . GLN B 1 264 ? 119.905 160.766 174.215 1.00 60.81  ?  253 GLN B CA  1 
ATOM   7218  C  C   . GLN B 1 264 ? 119.349 162.024 173.603 1.00 60.81  ?  253 GLN B C   1 
ATOM   7219  O  O   . GLN B 1 264 ? 119.573 163.109 174.123 1.00 60.81  ?  253 GLN B O   1 
ATOM   7220  C  CB  . GLN B 1 264 ? 121.373 161.010 174.518 1.00 60.81  ?  253 GLN B CB  1 
ATOM   7221  C  CG  . GLN B 1 264 ? 122.231 159.763 174.561 1.00 60.81  ?  253 GLN B CG  1 
ATOM   7222  C  CD  . GLN B 1 264 ? 123.706 160.083 174.434 1.00 60.81  ?  253 GLN B CD  1 
ATOM   7223  O  OE1 . GLN B 1 264 ? 124.526 159.200 174.191 1.00 60.81  ?  253 GLN B OE1 1 
ATOM   7224  N  NE2 . GLN B 1 264 ? 124.051 161.355 174.586 1.00 60.81  ?  253 GLN B NE2 1 
ATOM   7225  N  N   . ILE B 1 265 ? 118.607 161.900 172.515 1.00 62.58  ?  254 ILE B N   1 
ATOM   7226  C  CA  . ILE B 1 265 ? 118.131 163.084 171.809 1.00 62.58  ?  254 ILE B CA  1 
ATOM   7227  C  C   . ILE B 1 265 ? 117.403 164.067 172.714 1.00 62.58  ?  254 ILE B C   1 
ATOM   7228  O  O   . ILE B 1 265 ? 117.350 165.256 172.420 1.00 62.58  ?  254 ILE B O   1 
ATOM   7229  C  CB  . ILE B 1 265 ? 117.210 162.703 170.637 1.00 62.58  ?  254 ILE B CB  1 
ATOM   7230  C  CG1 . ILE B 1 265 ? 117.199 163.818 169.590 1.00 62.58  ?  254 ILE B CG1 1 
ATOM   7231  C  CG2 . ILE B 1 265 ? 115.806 162.391 171.136 1.00 62.58  ?  254 ILE B CG2 1 
ATOM   7232  C  CD1 . ILE B 1 265 ? 118.561 164.096 168.993 1.00 62.58  ?  254 ILE B CD1 1 
ATOM   7233  N  N   . GLU B 1 266 ? 116.844 163.581 173.812 1.00 64.58  ?  255 GLU B N   1 
ATOM   7234  C  CA  . GLU B 1 266 ? 116.136 164.456 174.735 1.00 64.58  ?  255 GLU B CA  1 
ATOM   7235  C  C   . GLU B 1 266 ? 117.095 165.444 175.399 1.00 64.58  ?  255 GLU B C   1 
ATOM   7236  O  O   . GLU B 1 266 ? 116.705 166.558 175.734 1.00 64.58  ?  255 GLU B O   1 
ATOM   7237  C  CB  . GLU B 1 266 ? 115.385 163.638 175.788 1.00 64.58  ?  255 GLU B CB  1 
ATOM   7238  C  CG  . GLU B 1 266 ? 116.275 162.899 176.775 1.00 64.58  ?  255 GLU B CG  1 
ATOM   7239  C  CD  . GLU B 1 266 ? 116.909 161.653 176.188 1.00 64.58  ?  255 GLU B CD  1 
ATOM   7240  O  OE1 . GLU B 1 266 ? 116.514 161.242 175.077 1.00 64.58  ?  255 GLU B OE1 1 
ATOM   7241  O  OE2 . GLU B 1 266 ? 117.799 161.077 176.848 1.00 64.58  -1 255 GLU B OE2 1 
ATOM   7242  N  N   . LYS B 1 267 ? 118.348 165.045 175.581 1.00 64.38  ?  256 LYS B N   1 
ATOM   7243  C  CA  . LYS B 1 267 ? 119.333 165.920 176.200 1.00 64.38  ?  256 LYS B CA  1 
ATOM   7244  C  C   . LYS B 1 267 ? 119.912 166.936 175.227 1.00 64.38  ?  256 LYS B C   1 
ATOM   7245  O  O   . LYS B 1 267 ? 120.940 167.547 175.527 1.00 64.38  ?  256 LYS B O   1 
ATOM   7246  C  CB  . LYS B 1 267 ? 120.474 165.102 176.798 1.00 64.38  ?  256 LYS B CB  1 
ATOM   7247  C  CG  . LYS B 1 267 ? 120.056 163.977 177.700 1.00 64.38  ?  256 LYS B CG  1 
ATOM   7248  C  CD  . LYS B 1 267 ? 121.279 163.352 178.338 1.00 64.38  ?  256 LYS B CD  1 
ATOM   7249  C  CE  . LYS B 1 267 ? 121.062 161.886 178.643 1.00 64.38  ?  256 LYS B CE  1 
ATOM   7250  N  NZ  . LYS B 1 267 ? 122.352 161.166 178.800 1.00 64.38  1  256 LYS B NZ  1 
ATOM   7251  N  N   . THR B 1 268 ? 119.282 167.125 174.074 1.00 62.49  ?  257 THR B N   1 
ATOM   7252  C  CA  . THR B 1 268 ? 119.825 167.983 173.032 1.00 62.49  ?  257 THR B CA  1 
ATOM   7253  C  C   . THR B 1 268 ? 119.923 169.425 173.500 1.00 62.49  ?  257 THR B C   1 
ATOM   7254  O  O   . THR B 1 268 ? 118.946 169.991 173.994 1.00 62.49  ?  257 THR B O   1 
ATOM   7255  C  CB  . THR B 1 268 ? 118.953 167.897 171.784 1.00 62.49  ?  257 THR B CB  1 
ATOM   7256  O  OG1 . THR B 1 268 ? 119.170 166.638 171.143 1.00 62.49  ?  257 THR B OG1 1 
ATOM   7257  C  CG2 . THR B 1 268 ? 119.276 169.013 170.818 1.00 62.49  ?  257 THR B CG2 1 
ATOM   7258  N  N   . ASN B 1 269 ? 121.066 170.059 173.242 1.00 62.43  ?  258 ASN B N   1 
ATOM   7259  C  CA  . ASN B 1 269 ? 121.212 171.478 173.533 1.00 62.43  ?  258 ASN B CA  1 
ATOM   7260  C  C   . ASN B 1 269 ? 120.592 172.212 172.371 1.00 62.43  ?  258 ASN B C   1 
ATOM   7261  O  O   . ASN B 1 269 ? 121.073 172.102 171.250 1.00 62.43  ?  258 ASN B O   1 
ATOM   7262  C  CB  . ASN B 1 269 ? 122.682 171.850 173.666 1.00 62.43  ?  258 ASN B CB  1 
ATOM   7263  C  CG  . ASN B 1 269 ? 122.899 173.323 173.962 1.00 62.43  ?  258 ASN B CG  1 
ATOM   7264  O  OD1 . ASN B 1 269 ? 122.279 174.194 173.355 1.00 62.43  ?  258 ASN B OD1 1 
ATOM   7265  N  ND2 . ASN B 1 269 ? 123.803 173.607 174.890 1.00 62.43  ?  258 ASN B ND2 1 
ATOM   7266  N  N   . ILE B 1 270 ? 119.522 172.953 172.617 1.00 62.23  ?  259 ILE B N   1 
ATOM   7267  C  CA  . ILE B 1 270 ? 118.813 173.629 171.531 1.00 62.23  ?  259 ILE B CA  1 
ATOM   7268  C  C   . ILE B 1 270 ? 119.601 174.767 170.913 1.00 62.23  ?  259 ILE B C   1 
ATOM   7269  O  O   . ILE B 1 270 ? 119.551 174.976 169.707 1.00 62.23  ?  259 ILE B O   1 
ATOM   7270  C  CB  . ILE B 1 270 ? 117.453 174.176 172.013 1.00 62.23  ?  259 ILE B CB  1 
ATOM   7271  C  CG1 . ILE B 1 270 ? 116.599 173.037 172.567 1.00 62.23  ?  259 ILE B CG1 1 
ATOM   7272  C  CG2 . ILE B 1 270 ? 116.726 174.888 170.885 1.00 62.23  ?  259 ILE B CG2 1 
ATOM   7273  C  CD1 . ILE B 1 270 ? 116.405 171.900 171.589 1.00 62.23  ?  259 ILE B CD1 1 
ATOM   7274  N  N   . ALA B 1 271 ? 120.324 175.507 171.736 1.00 62.50  ?  260 ALA B N   1 
ATOM   7275  C  CA  . ALA B 1 271 ? 121.078 176.642 171.233 1.00 62.50  ?  260 ALA B CA  1 
ATOM   7276  C  C   . ALA B 1 271 ? 122.081 176.176 170.197 1.00 62.50  ?  260 ALA B C   1 
ATOM   7277  O  O   . ALA B 1 271 ? 122.247 176.818 169.161 1.00 62.50  ?  260 ALA B O   1 
ATOM   7278  C  CB  . ALA B 1 271 ? 121.770 177.350 172.372 1.00 62.50  ?  260 ALA B CB  1 
ATOM   7279  N  N   . ASP B 1 272 ? 122.741 175.053 170.459 1.00 62.29  ?  261 ASP B N   1 
ATOM   7280  C  CA  . ASP B 1 272 ? 123.689 174.506 169.498 1.00 62.29  ?  261 ASP B CA  1 
ATOM   7281  C  C   . ASP B 1 272 ? 122.987 174.136 168.221 1.00 62.29  ?  261 ASP B C   1 
ATOM   7282  O  O   . ASP B 1 272 ? 123.446 174.475 167.134 1.00 62.29  ?  261 ASP B O   1 
ATOM   7283  C  CB  . ASP B 1 272 ? 124.384 173.278 170.071 1.00 62.29  ?  261 ASP B CB  1 
ATOM   7284  C  CG  . ASP B 1 272 ? 125.319 173.621 171.206 1.00 62.29  ?  261 ASP B CG  1 
ATOM   7285  O  OD1 . ASP B 1 272 ? 126.180 172.787 171.545 1.00 62.29  ?  261 ASP B OD1 1 
ATOM   7286  O  OD2 . ASP B 1 272 ? 125.200 174.734 171.753 1.00 62.29  -1 261 ASP B OD2 1 
ATOM   7287  N  N   . LEU B 1 273 ? 121.863 173.450 168.346 1.00 61.36  ?  262 LEU B N   1 
ATOM   7288  C  CA  . LEU B 1 273 ? 121.111 173.027 167.180 1.00 61.36  ?  262 LEU B CA  1 
ATOM   7289  C  C   . LEU B 1 273 ? 120.665 174.207 166.347 1.00 61.36  ?  262 LEU B C   1 
ATOM   7290  O  O   . LEU B 1 273 ? 120.838 174.211 165.134 1.00 61.36  ?  262 LEU B O   1 
ATOM   7291  C  CB  . LEU B 1 273 ? 119.894 172.226 167.630 1.00 61.36  ?  262 LEU B CB  1 
ATOM   7292  C  CG  . LEU B 1 273 ? 118.985 171.643 166.551 1.00 61.36  ?  262 LEU B CG  1 
ATOM   7293  C  CD1 . LEU B 1 273 ? 119.787 170.814 165.562 1.00 61.36  ?  262 LEU B CD1 1 
ATOM   7294  C  CD2 . LEU B 1 273 ? 117.899 170.801 167.198 1.00 61.36  ?  262 LEU B CD2 1 
ATOM   7295  N  N   . VAL B 1 274 ? 120.041 175.193 166.964 1.00 61.54  ?  263 VAL B N   1 
ATOM   7296  C  CA  . VAL B 1 274 ? 119.545 176.328 166.206 1.00 61.54  ?  263 VAL B CA  1 
ATOM   7297  C  C   . VAL B 1 274 ? 120.650 177.027 165.442 1.00 61.54  ?  263 VAL B C   1 
ATOM   7298  O  O   . VAL B 1 274 ? 120.492 177.349 164.283 1.00 61.54  ?  263 VAL B O   1 
ATOM   7299  C  CB  . VAL B 1 274 ? 118.799 177.330 167.094 1.00 61.54  ?  263 VAL B CB  1 
ATOM   7300  C  CG1 . VAL B 1 274 ? 118.392 178.551 166.291 1.00 61.54  ?  263 VAL B CG1 1 
ATOM   7301  C  CG2 . VAL B 1 274 ? 117.584 176.666 167.714 1.00 61.54  ?  263 VAL B CG2 1 
ATOM   7302  N  N   . THR B 1 275 ? 121.780 177.229 166.096 1.00 62.83  ?  264 THR B N   1 
ATOM   7303  C  CA  . THR B 1 275 ? 122.911 177.893 165.486 1.00 62.83  ?  264 THR B CA  1 
ATOM   7304  C  C   . THR B 1 275 ? 123.418 177.112 164.302 1.00 62.83  ?  264 THR B C   1 
ATOM   7305  O  O   . THR B 1 275 ? 123.759 177.683 163.279 1.00 62.83  ?  264 THR B O   1 
ATOM   7306  C  CB  . THR B 1 275 ? 124.061 177.989 166.484 1.00 62.83  ?  264 THR B CB  1 
ATOM   7307  O  OG1 . THR B 1 275 ? 123.533 178.294 167.776 1.00 62.83  ?  264 THR B OG1 1 
ATOM   7308  C  CG2 . THR B 1 275 ? 125.036 179.055 166.062 1.00 62.83  ?  264 THR B CG2 1 
ATOM   7309  N  N   . ALA B 1 276 ? 123.491 175.800 164.456 1.00 61.06  ?  265 ALA B N   1 
ATOM   7310  C  CA  . ALA B 1 276 ? 123.943 174.934 163.393 1.00 61.06  ?  265 ALA B CA  1 
ATOM   7311  C  C   . ALA B 1 276 ? 122.998 174.980 162.209 1.00 61.06  ?  265 ALA B C   1 
ATOM   7312  O  O   . ALA B 1 276 ? 123.437 175.016 161.082 1.00 61.06  ?  265 ALA B O   1 
ATOM   7313  C  CB  . ALA B 1 276 ? 124.079 173.513 163.904 1.00 61.06  ?  265 ALA B CB  1 
ATOM   7314  N  N   . LEU B 1 277 ? 121.696 174.970 162.462 1.00 62.59  ?  266 LEU B N   1 
ATOM   7315  C  CA  . LEU B 1 277 ? 120.719 174.999 161.383 1.00 62.59  ?  266 LEU B CA  1 
ATOM   7316  C  C   . LEU B 1 277 ? 120.766 176.275 160.578 1.00 62.59  ?  266 LEU B C   1 
ATOM   7317  O  O   . LEU B 1 277 ? 120.682 176.245 159.364 1.00 62.59  ?  266 LEU B O   1 
ATOM   7318  C  CB  . LEU B 1 277 ? 119.312 174.785 161.929 1.00 62.59  ?  266 LEU B CB  1 
ATOM   7319  C  CG  . LEU B 1 277 ? 118.968 173.354 162.321 1.00 62.59  ?  266 LEU B CG  1 
ATOM   7320  C  CD1 . LEU B 1 277 ? 117.533 173.279 162.802 1.00 62.59  ?  266 LEU B CD1 1 
ATOM   7321  C  CD2 . LEU B 1 277 ? 119.212 172.397 161.168 1.00 62.59  ?  266 LEU B CD2 1 
ATOM   7322  N  N   . ILE B 1 278 ? 120.889 177.398 161.267 1.00 63.60  ?  267 ILE B N   1 
ATOM   7323  C  CA  . ILE B 1 278 ? 120.957 178.686 160.615 1.00 63.60  ?  267 ILE B CA  1 
ATOM   7324  C  C   . ILE B 1 278 ? 122.194 178.813 159.754 1.00 63.60  ?  267 ILE B C   1 
ATOM   7325  O  O   . ILE B 1 278 ? 122.132 179.315 158.644 1.00 63.60  ?  267 ILE B O   1 
ATOM   7326  C  CB  . ILE B 1 278 ? 120.957 179.808 161.650 1.00 63.60  ?  267 ILE B CB  1 
ATOM   7327  C  CG1 . ILE B 1 278 ? 119.576 179.936 162.275 1.00 63.60  ?  267 ILE B CG1 1 
ATOM   7328  C  CG2 . ILE B 1 278 ? 121.394 181.113 161.017 1.00 63.60  ?  267 ILE B CG2 1 
ATOM   7329  C  CD1 . ILE B 1 278 ? 119.584 180.633 163.611 1.00 63.60  ?  267 ILE B CD1 1 
ATOM   7330  N  N   . VAL B 1 279 ? 123.327 178.368 160.276 1.00 64.21  ?  268 VAL B N   1 
ATOM   7331  C  CA  . VAL B 1 279 ? 124.563 178.425 159.521 1.00 64.21  ?  268 VAL B CA  1 
ATOM   7332  C  C   . VAL B 1 279 ? 124.496 177.524 158.311 1.00 64.21  ?  268 VAL B C   1 
ATOM   7333  O  O   . VAL B 1 279 ? 124.927 177.892 157.235 1.00 64.21  ?  268 VAL B O   1 
ATOM   7334  C  CB  . VAL B 1 279 ? 125.783 178.056 160.384 1.00 64.21  ?  268 VAL B CB  1 
ATOM   7335  C  CG1 . VAL B 1 279 ? 126.940 177.620 159.505 1.00 64.21  ?  268 VAL B CG1 1 
ATOM   7336  C  CG2 . VAL B 1 279 ? 126.184 179.232 161.256 1.00 64.21  ?  268 VAL B CG2 1 
ATOM   7337  N  N   . LEU B 1 280 ? 123.934 176.341 158.499 1.00 64.12  ?  269 LEU B N   1 
ATOM   7338  C  CA  . LEU B 1 280 ? 123.806 175.357 157.438 1.00 64.12  ?  269 LEU B CA  1 
ATOM   7339  C  C   . LEU B 1 280 ? 122.856 175.861 156.365 1.00 64.12  ?  269 LEU B C   1 
ATOM   7340  O  O   . LEU B 1 280 ? 123.086 175.671 155.186 1.00 64.12  ?  269 LEU B O   1 
ATOM   7341  C  CB  . LEU B 1 280 ? 123.328 174.034 158.021 1.00 64.12  ?  269 LEU B CB  1 
ATOM   7342  C  CG  . LEU B 1 280 ? 123.064 172.843 157.111 1.00 64.12  ?  269 LEU B CG  1 
ATOM   7343  C  CD1 . LEU B 1 280 ? 124.320 172.479 156.353 1.00 64.12  ?  269 LEU B CD1 1 
ATOM   7344  C  CD2 . LEU B 1 280 ? 122.601 171.673 157.953 1.00 64.12  ?  269 LEU B CD2 1 
ATOM   7345  N  N   . LEU B 1 281 ? 121.781 176.505 156.785 1.00 67.36  ?  270 LEU B N   1 
ATOM   7346  C  CA  . LEU B 1 281 ? 120.820 177.068 155.855 1.00 67.36  ?  270 LEU B CA  1 
ATOM   7347  C  C   . LEU B 1 281 ? 121.395 178.220 155.063 1.00 67.36  ?  270 LEU B C   1 
ATOM   7348  O  O   . LEU B 1 281 ? 121.334 178.229 153.835 1.00 67.36  ?  270 LEU B O   1 
ATOM   7349  C  CB  . LEU B 1 281 ? 119.605 177.561 156.628 1.00 67.36  ?  270 LEU B CB  1 
ATOM   7350  C  CG  . LEU B 1 281 ? 118.562 178.335 155.824 1.00 67.36  ?  270 LEU B CG  1 
ATOM   7351  C  CD1 . LEU B 1 281 ? 117.950 177.446 154.753 1.00 67.36  ?  270 LEU B CD1 1 
ATOM   7352  C  CD2 . LEU B 1 281 ? 117.486 178.884 156.746 1.00 67.36  ?  270 LEU B CD2 1 
ATOM   7353  N  N   . VAL B 1 282 ? 121.972 179.189 155.757 1.00 68.03  ?  271 VAL B N   1 
ATOM   7354  C  CA  . VAL B 1 282 ? 122.511 180.353 155.079 1.00 68.03  ?  271 VAL B CA  1 
ATOM   7355  C  C   . VAL B 1 282 ? 123.621 179.945 154.134 1.00 68.03  ?  271 VAL B C   1 
ATOM   7356  O  O   . VAL B 1 282 ? 123.640 180.362 152.978 1.00 68.03  ?  271 VAL B O   1 
ATOM   7357  C  CB  . VAL B 1 282 ? 123.049 181.384 156.078 1.00 68.03  ?  271 VAL B CB  1 
ATOM   7358  C  CG1 . VAL B 1 282 ? 123.791 182.493 155.352 1.00 68.03  ?  271 VAL B CG1 1 
ATOM   7359  C  CG2 . VAL B 1 282 ? 121.916 181.945 156.919 1.00 68.03  ?  271 VAL B CG2 1 
ATOM   7360  N  N   . VAL B 1 283 ? 124.534 179.110 154.607 1.00 69.11  ?  272 VAL B N   1 
ATOM   7361  C  CA  . VAL B 1 283 ? 125.666 178.728 153.781 1.00 69.11  ?  272 VAL B CA  1 
ATOM   7362  C  C   . VAL B 1 283 ? 125.188 178.026 152.524 1.00 69.11  ?  272 VAL B C   1 
ATOM   7363  O  O   . VAL B 1 283 ? 125.652 178.332 151.430 1.00 69.11  ?  272 VAL B O   1 
ATOM   7364  C  CB  . VAL B 1 283 ? 126.653 177.833 154.552 1.00 69.11  ?  272 VAL B CB  1 
ATOM   7365  C  CG1 . VAL B 1 283 ? 127.614 177.145 153.598 1.00 69.11  ?  272 VAL B CG1 1 
ATOM   7366  C  CG2 . VAL B 1 283 ? 127.407 178.653 155.587 1.00 69.11  ?  272 VAL B CG2 1 
ATOM   7367  N  N   . SER B 1 284 ? 124.243 177.108 152.668 1.00 72.30  ?  273 SER B N   1 
ATOM   7368  C  CA  . SER B 1 284 ? 123.750 176.362 151.519 1.00 72.30  ?  273 SER B CA  1 
ATOM   7369  C  C   . SER B 1 284 ? 123.151 177.287 150.477 1.00 72.30  ?  273 SER B C   1 
ATOM   7370  O  O   . SER B 1 284 ? 123.479 177.194 149.298 1.00 72.30  ?  273 SER B O   1 
ATOM   7371  C  CB  . SER B 1 284 ? 122.700 175.352 151.959 1.00 72.30  ?  273 SER B CB  1 
ATOM   7372  O  OG  . SER B 1 284 ? 121.563 176.007 152.492 1.00 72.30  ?  273 SER B OG  1 
ATOM   7373  N  N   . ILE B 1 285 ? 122.287 178.194 150.912 1.00 74.70  ?  274 ILE B N   1 
ATOM   7374  C  CA  . ILE B 1 285 ? 121.646 179.108 149.983 1.00 74.70  ?  274 ILE B CA  1 
ATOM   7375  C  C   . ILE B 1 285 ? 122.667 179.976 149.261 1.00 74.70  ?  274 ILE B C   1 
ATOM   7376  O  O   . ILE B 1 285 ? 122.622 180.109 148.039 1.00 74.70  ?  274 ILE B O   1 
ATOM   7377  C  CB  . ILE B 1 285 ? 120.638 180.012 150.710 1.00 74.70  ?  274 ILE B CB  1 
ATOM   7378  C  CG1 . ILE B 1 285 ? 119.534 179.169 151.345 1.00 74.70  ?  274 ILE B CG1 1 
ATOM   7379  C  CG2 . ILE B 1 285 ? 120.049 181.033 149.750 1.00 74.70  ?  274 ILE B CG2 1 
ATOM   7380  C  CD1 . ILE B 1 285 ? 118.524 179.984 152.120 1.00 74.70  ?  274 ILE B CD1 1 
ATOM   7381  N  N   . VAL B 1 286 ? 123.597 180.562 150.007 1.00 75.59  ?  275 VAL B N   1 
ATOM   7382  C  CA  . VAL B 1 286 ? 124.586 181.439 149.400 1.00 75.59  ?  275 VAL B CA  1 
ATOM   7383  C  C   . VAL B 1 286 ? 125.545 180.652 148.524 1.00 75.59  ?  275 VAL B C   1 
ATOM   7384  O  O   . VAL B 1 286 ? 126.007 181.156 147.507 1.00 75.59  ?  275 VAL B O   1 
ATOM   7385  C  CB  . VAL B 1 286 ? 125.363 182.234 150.459 1.00 75.59  ?  275 VAL B CB  1 
ATOM   7386  C  CG1 . VAL B 1 286 ? 126.460 183.062 149.808 1.00 75.59  ?  275 VAL B CG1 1 
ATOM   7387  C  CG2 . VAL B 1 286 ? 124.416 183.122 151.248 1.00 75.59  ?  275 VAL B CG2 1 
ATOM   7388  N  N   . LYS B 1 287 ? 125.842 179.416 148.906 1.00 75.78  ?  276 LYS B N   1 
ATOM   7389  C  CA  . LYS B 1 287 ? 126.704 178.581 148.079 1.00 75.78  ?  276 LYS B CA  1 
ATOM   7390  C  C   . LYS B 1 287 ? 126.058 178.420 146.726 1.00 75.78  ?  276 LYS B C   1 
ATOM   7391  O  O   . LYS B 1 287 ? 126.732 178.462 145.702 1.00 75.78  ?  276 LYS B O   1 
ATOM   7392  C  CB  . LYS B 1 287 ? 126.932 177.214 148.710 1.00 75.78  ?  276 LYS B CB  1 
ATOM   7393  C  CG  . LYS B 1 287 ? 128.135 177.133 149.633 1.00 75.78  ?  276 LYS B CG  1 
ATOM   7394  C  CD  . LYS B 1 287 ? 128.323 175.715 150.147 1.00 75.78  ?  276 LYS B CD  1 
ATOM   7395  C  CE  . LYS B 1 287 ? 129.722 175.504 150.703 1.00 75.78  ?  276 LYS B CE  1 
ATOM   7396  N  NZ  . LYS B 1 287 ? 129.901 174.152 151.297 1.00 75.78  1  276 LYS B NZ  1 
ATOM   7397  N  N   . GLU B 1 288 ? 124.748 178.196 146.706 1.00 82.59  ?  277 GLU B N   1 
ATOM   7398  C  CA  . GLU B 1 288 ? 124.017 178.016 145.456 1.00 82.59  ?  277 GLU B CA  1 
ATOM   7399  C  C   . GLU B 1 288 ? 124.122 179.241 144.577 1.00 82.59  ?  277 GLU B C   1 
ATOM   7400  O  O   . GLU B 1 288 ? 124.313 179.137 143.375 1.00 82.59  ?  277 GLU B O   1 
ATOM   7401  C  CB  . GLU B 1 288 ? 122.544 177.741 145.724 1.00 82.59  ?  277 GLU B CB  1 
ATOM   7402  C  CG  . GLU B 1 288 ? 122.215 176.289 146.014 1.00 82.59  ?  277 GLU B CG  1 
ATOM   7403  C  CD  . GLU B 1 288 ? 120.836 176.137 146.613 1.00 82.59  ?  277 GLU B CD  1 
ATOM   7404  O  OE1 . GLU B 1 288 ? 119.974 176.992 146.329 1.00 82.59  ?  277 GLU B OE1 1 
ATOM   7405  O  OE2 . GLU B 1 288 ? 120.614 175.174 147.374 1.00 82.59  -1 277 GLU B OE2 1 
ATOM   7406  N  N   . ILE B 1 289 ? 124.032 180.411 145.192 1.00 82.96  ?  278 ILE B N   1 
ATOM   7407  C  CA  . ILE B 1 289 ? 124.107 181.669 144.471 1.00 82.96  ?  278 ILE B CA  1 
ATOM   7408  C  C   . ILE B 1 289 ? 125.452 181.829 143.779 1.00 82.96  ?  278 ILE B C   1 
ATOM   7409  O  O   . ILE B 1 289 ? 125.525 182.344 142.679 1.00 82.96  ?  278 ILE B O   1 
ATOM   7410  C  CB  . ILE B 1 289 ? 123.833 182.856 145.400 1.00 82.96  ?  278 ILE B CB  1 
ATOM   7411  C  CG1 . ILE B 1 289 ? 122.390 182.799 145.889 1.00 82.96  ?  278 ILE B CG1 1 
ATOM   7412  C  CG2 . ILE B 1 289 ? 124.110 184.169 144.692 1.00 82.96  ?  278 ILE B CG2 1 
ATOM   7413  C  CD1 . ILE B 1 289 ? 122.071 183.806 146.962 1.00 82.96  ?  278 ILE B CD1 1 
ATOM   7414  N  N   . ASN B 1 290 ? 126.524 181.405 144.424 1.00 85.48  ?  279 ASN B N   1 
ATOM   7415  C  CA  . ASN B 1 290 ? 127.823 181.513 143.803 1.00 85.48  ?  279 ASN B CA  1 
ATOM   7416  C  C   . ASN B 1 290 ? 127.891 180.695 142.525 1.00 85.48  ?  279 ASN B C   1 
ATOM   7417  O  O   . ASN B 1 290 ? 128.443 181.149 141.532 1.00 85.48  ?  279 ASN B O   1 
ATOM   7418  C  CB  . ASN B 1 290 ? 128.898 181.081 144.786 1.00 85.48  ?  279 ASN B CB  1 
ATOM   7419  C  CG  . ASN B 1 290 ? 128.989 182.009 145.961 1.00 85.48  ?  279 ASN B CG  1 
ATOM   7420  O  OD1 . ASN B 1 290 ? 129.675 181.737 146.933 1.00 85.48  ?  279 ASN B OD1 1 
ATOM   7421  N  ND2 . ASN B 1 290 ? 128.280 183.119 145.877 1.00 85.48  ?  279 ASN B ND2 1 
ATOM   7422  N  N   . GLN B 1 291 ? 127.365 179.478 142.546 1.00 89.76  ?  280 GLN B N   1 
ATOM   7423  C  CA  . GLN B 1 291 ? 127.347 178.678 141.327 1.00 89.76  ?  280 GLN B CA  1 
ATOM   7424  C  C   . GLN B 1 291 ? 126.424 179.247 140.245 1.00 89.76  ?  280 GLN B C   1 
ATOM   7425  O  O   . GLN B 1 291 ? 126.776 179.260 139.069 1.00 89.76  ?  280 GLN B O   1 
ATOM   7426  C  CB  . GLN B 1 291 ? 126.997 177.230 141.632 1.00 89.76  ?  280 GLN B CB  1 
ATOM   7427  C  CG  . GLN B 1 291 ? 127.915 176.613 142.668 1.00 89.76  ?  280 GLN B CG  1 
ATOM   7428  C  CD  . GLN B 1 291 ? 128.491 175.295 142.214 1.00 89.76  ?  280 GLN B CD  1 
ATOM   7429  O  OE1 . GLN B 1 291 ? 128.705 175.082 141.021 1.00 89.76  ?  280 GLN B OE1 1 
ATOM   7430  N  NE2 . GLN B 1 291 ? 128.755 174.404 143.162 1.00 89.76  ?  280 GLN B NE2 1 
ATOM   7431  N  N   . ARG B 1 292 ? 125.224 179.671 140.632 1.00 91.63  ?  281 ARG B N   1 
ATOM   7432  C  CA  . ARG B 1 292 ? 124.293 180.255 139.671 1.00 91.63  ?  281 ARG B CA  1 
ATOM   7433  C  C   . ARG B 1 292 ? 124.699 181.620 139.129 1.00 91.63  ?  281 ARG B C   1 
ATOM   7434  O  O   . ARG B 1 292 ? 124.630 181.874 137.930 1.00 91.63  ?  281 ARG B O   1 
ATOM   7435  C  CB  . ARG B 1 292 ? 122.882 180.361 140.257 1.00 91.63  ?  281 ARG B CB  1 
ATOM   7436  C  CG  . ARG B 1 292 ? 122.336 179.071 140.839 1.00 91.63  ?  281 ARG B CG  1 
ATOM   7437  C  CD  . ARG B 1 292 ? 122.640 177.875 139.959 1.00 91.63  ?  281 ARG B CD  1 
ATOM   7438  N  NE  . ARG B 1 292 ? 122.520 176.625 140.701 1.00 91.63  ?  281 ARG B NE  1 
ATOM   7439  C  CZ  . ARG B 1 292 ? 122.057 175.489 140.188 1.00 91.63  ?  281 ARG B CZ  1 
ATOM   7440  N  NH1 . ARG B 1 292 ? 121.991 174.399 140.938 1.00 91.63  1  281 ARG B NH1 1 
ATOM   7441  N  NH2 . ARG B 1 292 ? 121.651 175.445 138.928 1.00 91.63  ?  281 ARG B NH2 1 
ATOM   7442  N  N   . PHE B 1 293 ? 125.162 182.509 139.995 1.00 93.38  ?  282 PHE B N   1 
ATOM   7443  C  CA  . PHE B 1 293 ? 125.524 183.853 139.549 1.00 93.38  ?  282 PHE B CA  1 
ATOM   7444  C  C   . PHE B 1 293 ? 126.994 184.171 139.292 1.00 93.38  ?  282 PHE B C   1 
ATOM   7445  O  O   . PHE B 1 293 ? 127.415 185.290 139.534 1.00 93.38  ?  282 PHE B O   1 
ATOM   7446  C  CB  . PHE B 1 293 ? 124.964 184.888 140.517 1.00 93.38  ?  282 PHE B CB  1 
ATOM   7447  C  CG  . PHE B 1 293 ? 123.529 185.204 140.286 1.00 93.38  ?  282 PHE B CG  1 
ATOM   7448  C  CD1 . PHE B 1 293 ? 123.066 186.501 140.414 1.00 93.38  ?  282 PHE B CD1 1 
ATOM   7449  C  CD2 . PHE B 1 293 ? 122.644 184.207 139.921 1.00 93.38  ?  282 PHE B CD2 1 
ATOM   7450  C  CE1 . PHE B 1 293 ? 121.738 186.798 140.197 1.00 93.38  ?  282 PHE B CE1 1 
ATOM   7451  C  CE2 . PHE B 1 293 ? 121.313 184.496 139.702 1.00 93.38  ?  282 PHE B CE2 1 
ATOM   7452  C  CZ  . PHE B 1 293 ? 120.861 185.794 139.838 1.00 93.38  ?  282 PHE B CZ  1 
ATOM   7453  N  N   . LYS B 1 294 ? 127.755 183.226 138.754 1.00 94.86  ?  283 LYS B N   1 
ATOM   7454  C  CA  . LYS B 1 294 ? 129.173 183.475 138.473 1.00 94.86  ?  283 LYS B CA  1 
ATOM   7455  C  C   . LYS B 1 294 ? 129.374 184.582 137.436 1.00 94.86  ?  283 LYS B C   1 
ATOM   7456  O  O   . LYS B 1 294 ? 130.316 185.365 137.518 1.00 94.86  ?  283 LYS B O   1 
ATOM   7457  C  CB  . LYS B 1 294 ? 129.864 182.203 137.990 1.00 94.86  ?  283 LYS B CB  1 
ATOM   7458  C  CG  . LYS B 1 294 ? 129.646 180.997 138.880 1.00 94.86  ?  283 LYS B CG  1 
ATOM   7459  C  CD  . LYS B 1 294 ? 130.725 179.961 138.635 1.00 94.86  ?  283 LYS B CD  1 
ATOM   7460  C  CE  . LYS B 1 294 ? 132.102 180.540 138.900 1.00 94.86  ?  283 LYS B CE  1 
ATOM   7461  N  NZ  . LYS B 1 294 ? 133.170 179.584 138.505 1.00 94.86  1  283 LYS B NZ  1 
ATOM   7462  N  N   . ASP B 1 295 ? 128.494 184.628 136.448 1.00 99.46  ?  284 ASP B N   1 
ATOM   7463  C  CA  . ASP B 1 295 ? 128.564 185.635 135.409 1.00 99.46  ?  284 ASP B CA  1 
ATOM   7464  C  C   . ASP B 1 295 ? 128.322 187.024 136.000 1.00 99.46  ?  284 ASP B C   1 
ATOM   7465  O  O   . ASP B 1 295 ? 129.016 187.977 135.665 1.00 99.46  ?  284 ASP B O   1 
ATOM   7466  C  CB  . ASP B 1 295 ? 127.501 185.352 134.350 1.00 99.46  ?  284 ASP B CB  1 
ATOM   7467  N  N   . LYS B 1 296 ? 127.351 187.134 136.897 1.00 98.64  ?  285 LYS B N   1 
ATOM   7468  C  CA  . LYS B 1 296 ? 127.017 188.415 137.508 1.00 98.64  ?  285 LYS B CA  1 
ATOM   7469  C  C   . LYS B 1 296 ? 127.854 188.787 138.730 1.00 98.64  ?  285 LYS B C   1 
ATOM   7470  O  O   . LYS B 1 296 ? 127.753 189.907 139.227 1.00 98.64  ?  285 LYS B O   1 
ATOM   7471  C  CB  . LYS B 1 296 ? 125.531 188.460 137.865 1.00 98.64  ?  285 LYS B CB  1 
ATOM   7472  N  N   . LEU B 1 297 ? 128.671 187.855 139.218 1.00 95.71  ?  286 LEU B N   1 
ATOM   7473  C  CA  . LEU B 1 297 ? 129.495 188.123 140.396 1.00 95.71  ?  286 LEU B CA  1 
ATOM   7474  C  C   . LEU B 1 297 ? 130.960 188.334 140.060 1.00 95.71  ?  286 LEU B C   1 
ATOM   7475  O  O   . LEU B 1 297 ? 131.561 187.544 139.335 1.00 95.71  ?  286 LEU B O   1 
ATOM   7476  C  CB  . LEU B 1 297 ? 129.352 187.012 141.439 1.00 95.71  ?  286 LEU B CB  1 
ATOM   7477  C  CG  . LEU B 1 297 ? 128.028 186.977 142.206 1.00 95.71  ?  286 LEU B CG  1 
ATOM   7478  C  CD1 . LEU B 1 297 ? 127.746 185.584 142.739 1.00 95.71  ?  286 LEU B CD1 1 
ATOM   7479  C  CD2 . LEU B 1 297 ? 127.995 188.011 143.319 1.00 95.71  ?  286 LEU B CD2 1 
ATOM   7480  N  N   . PRO B 1 298 ? 131.540 189.409 140.601 1.00 94.71  ?  287 PRO B N   1 
ATOM   7481  C  CA  . PRO B 1 298 ? 132.944 189.768 140.388 1.00 94.71  ?  287 PRO B CA  1 
ATOM   7482  C  C   . PRO B 1 298 ? 133.837 188.837 141.188 1.00 94.71  ?  287 PRO B C   1 
ATOM   7483  O  O   . PRO B 1 298 ? 134.950 188.519 140.776 1.00 94.71  ?  287 PRO B O   1 
ATOM   7484  C  CB  . PRO B 1 298 ? 133.029 191.193 140.931 1.00 94.71  ?  287 PRO B CB  1 
ATOM   7485  C  CG  . PRO B 1 298 ? 131.915 191.298 141.914 1.00 94.71  ?  287 PRO B CG  1 
ATOM   7486  C  CD  . PRO B 1 298 ? 130.822 190.395 141.426 1.00 94.71  ?  287 PRO B CD  1 
ATOM   7487  N  N   . VAL B 1 299 ? 133.335 188.407 142.336 1.00 90.81  ?  288 VAL B N   1 
ATOM   7488  C  CA  . VAL B 1 299 ? 134.058 187.494 143.202 1.00 90.81  ?  288 VAL B CA  1 
ATOM   7489  C  C   . VAL B 1 299 ? 133.041 186.795 144.091 1.00 90.81  ?  288 VAL B C   1 
ATOM   7490  O  O   . VAL B 1 299 ? 132.071 187.408 144.531 1.00 90.81  ?  288 VAL B O   1 
ATOM   7491  C  CB  . VAL B 1 299 ? 135.139 188.208 144.041 1.00 90.81  ?  288 VAL B CB  1 
ATOM   7492  C  CG1 . VAL B 1 299 ? 134.521 189.215 144.992 1.00 90.81  ?  288 VAL B CG1 1 
ATOM   7493  C  CG2 . VAL B 1 299 ? 135.983 187.197 144.795 1.00 90.81  ?  288 VAL B CG2 1 
ATOM   7494  N  N   . PRO B 1 300 ? 133.254 185.499 144.331 1.00 86.21  ?  289 PRO B N   1 
ATOM   7495  C  CA  . PRO B 1 300 ? 132.417 184.609 145.134 1.00 86.21  ?  289 PRO B CA  1 
ATOM   7496  C  C   . PRO B 1 300 ? 132.241 185.140 146.547 1.00 86.21  ?  289 PRO B C   1 
ATOM   7497  O  O   . PRO B 1 300 ? 133.205 185.617 147.139 1.00 86.21  ?  289 PRO B O   1 
ATOM   7498  C  CB  . PRO B 1 300 ? 133.218 183.298 145.158 1.00 86.21  ?  289 PRO B CB  1 
ATOM   7499  C  CG  . PRO B 1 300 ? 134.578 183.637 144.642 1.00 86.21  ?  289 PRO B CG  1 
ATOM   7500  C  CD  . PRO B 1 300 ? 134.374 184.783 143.706 1.00 86.21  ?  289 PRO B CD  1 
ATOM   7501  N  N   . ILE B 1 301 ? 131.029 185.063 147.081 1.00 80.93  ?  290 ILE B N   1 
ATOM   7502  C  CA  . ILE B 1 301 ? 130.787 185.496 148.449 1.00 80.93  ?  290 ILE B CA  1 
ATOM   7503  C  C   . ILE B 1 301 ? 131.342 184.475 149.428 1.00 80.93  ?  290 ILE B C   1 
ATOM   7504  O  O   . ILE B 1 301 ? 131.032 183.293 149.329 1.00 80.93  ?  290 ILE B O   1 
ATOM   7505  C  CB  . ILE B 1 301 ? 129.284 185.677 148.715 1.00 80.93  ?  290 ILE B CB  1 
ATOM   7506  C  CG1 . ILE B 1 301 ? 128.667 186.606 147.670 1.00 80.93  ?  290 ILE B CG1 1 
ATOM   7507  C  CG2 . ILE B 1 301 ? 129.053 186.210 150.121 1.00 80.93  ?  290 ILE B CG2 1 
ATOM   7508  C  CD1 . ILE B 1 301 ? 127.168 186.749 147.799 1.00 80.93  ?  290 ILE B CD1 1 
ATOM   7509  N  N   . PRO B 1 302 ? 132.167 184.924 150.379 1.00 74.90  ?  291 PRO B N   1 
ATOM   7510  C  CA  . PRO B 1 302 ? 132.726 184.011 151.380 1.00 74.90  ?  291 PRO B CA  1 
ATOM   7511  C  C   . PRO B 1 302 ? 131.741 183.770 152.514 1.00 74.90  ?  291 PRO B C   1 
ATOM   7512  O  O   . PRO B 1 302 ? 131.912 184.324 153.596 1.00 74.90  ?  291 PRO B O   1 
ATOM   7513  C  CB  . PRO B 1 302 ? 133.952 184.765 151.883 1.00 74.90  ?  291 PRO B CB  1 
ATOM   7514  C  CG  . PRO B 1 302 ? 133.603 186.204 151.706 1.00 74.90  ?  291 PRO B CG  1 
ATOM   7515  C  CD  . PRO B 1 302 ? 132.663 186.301 150.537 1.00 74.90  ?  291 PRO B CD  1 
ATOM   7516  N  N   . ILE B 1 303 ? 130.727 182.949 152.276 1.00 70.54  ?  292 ILE B N   1 
ATOM   7517  C  CA  . ILE B 1 303 ? 129.699 182.721 153.285 1.00 70.54  ?  292 ILE B CA  1 
ATOM   7518  C  C   . ILE B 1 303 ? 130.221 181.932 154.482 1.00 70.54  ?  292 ILE B C   1 
ATOM   7519  O  O   . ILE B 1 303 ? 129.799 182.164 155.610 1.00 70.54  ?  292 ILE B O   1 
ATOM   7520  C  CB  . ILE B 1 303 ? 128.466 182.008 152.685 1.00 70.54  ?  292 ILE B CB  1 
ATOM   7521  C  CG1 . ILE B 1 303 ? 127.317 182.008 153.693 1.00 70.54  ?  292 ILE B CG1 1 
ATOM   7522  C  CG2 . ILE B 1 303 ? 128.813 180.595 152.243 1.00 70.54  ?  292 ILE B CG2 1 
ATOM   7523  C  CD1 . ILE B 1 303 ? 126.946 183.393 154.175 1.00 70.54  ?  292 ILE B CD1 1 
ATOM   7524  N  N   . GLU B 1 304 ? 131.227 181.066 154.293 1.00 67.31  ?  293 GLU B N   1 
ATOM   7525  C  CA  . GLU B 1 304 ? 131.733 180.199 155.353 1.00 67.31  ?  293 GLU B CA  1 
ATOM   7526  C  C   . GLU B 1 304 ? 132.587 180.965 156.326 1.00 67.31  ?  293 GLU B C   1 
ATOM   7527  O  O   . GLU B 1 304 ? 132.586 180.695 157.519 1.00 67.31  ?  293 GLU B O   1 
ATOM   7528  C  CB  . GLU B 1 304 ? 132.506 179.017 154.778 1.00 67.31  ?  293 GLU B CB  1 
ATOM   7529  C  CG  . GLU B 1 304 ? 131.678 178.035 153.973 1.00 67.31  ?  293 GLU B CG  1 
ATOM   7530  C  CD  . GLU B 1 304 ? 131.675 178.352 152.494 1.00 67.31  ?  293 GLU B CD  1 
ATOM   7531  O  OE1 . GLU B 1 304 ? 131.241 177.496 151.704 1.00 67.31  ?  293 GLU B OE1 1 
ATOM   7532  O  OE2 . GLU B 1 304 ? 132.111 179.455 152.118 1.00 67.31  -1 293 GLU B OE2 1 
ATOM   7533  N  N   . PHE B 1 305 ? 133.368 181.887 155.797 1.00 65.33  ?  294 PHE B N   1 
ATOM   7534  C  CA  . PHE B 1 305 ? 134.151 182.768 156.650 1.00 65.33  ?  294 PHE B CA  1 
ATOM   7535  C  C   . PHE B 1 305 ? 133.266 183.786 157.353 1.00 65.33  ?  294 PHE B C   1 
ATOM   7536  O  O   . PHE B 1 305 ? 133.441 184.047 158.548 1.00 65.33  ?  294 PHE B O   1 
ATOM   7537  C  CB  . PHE B 1 305 ? 135.222 183.467 155.817 1.00 65.33  ?  294 PHE B CB  1 
ATOM   7538  C  CG  . PHE B 1 305 ? 136.180 184.276 156.623 1.00 65.33  ?  294 PHE B CG  1 
ATOM   7539  C  CD1 . PHE B 1 305 ? 136.925 183.690 157.622 1.00 65.33  ?  294 PHE B CD1 1 
ATOM   7540  C  CD2 . PHE B 1 305 ? 136.339 185.622 156.384 1.00 65.33  ?  294 PHE B CD2 1 
ATOM   7541  C  CE1 . PHE B 1 305 ? 137.809 184.430 158.363 1.00 65.33  ?  294 PHE B CE1 1 
ATOM   7542  C  CE2 . PHE B 1 305 ? 137.221 186.364 157.124 1.00 65.33  ?  294 PHE B CE2 1 
ATOM   7543  C  CZ  . PHE B 1 305 ? 137.958 185.766 158.112 1.00 65.33  ?  294 PHE B CZ  1 
ATOM   7544  N  N   . ILE B 1 306 ? 132.316 184.372 156.627 1.00 67.49  ?  295 ILE B N   1 
ATOM   7545  C  CA  . ILE B 1 306 ? 131.402 185.335 157.230 1.00 67.49  ?  295 ILE B CA  1 
ATOM   7546  C  C   . ILE B 1 306 ? 130.603 184.679 158.343 1.00 67.49  ?  295 ILE B C   1 
ATOM   7547  O  O   . ILE B 1 306 ? 130.406 185.263 159.413 1.00 67.49  ?  295 ILE B O   1 
ATOM   7548  C  CB  . ILE B 1 306 ? 130.483 185.939 156.155 1.00 67.49  ?  295 ILE B CB  1 
ATOM   7549  C  CG1 . ILE B 1 306 ? 131.263 186.914 155.280 1.00 67.49  ?  295 ILE B CG1 1 
ATOM   7550  C  CG2 . ILE B 1 306 ? 129.295 186.632 156.787 1.00 67.49  ?  295 ILE B CG2 1 
ATOM   7551  C  CD1 . ILE B 1 306 ? 130.505 187.360 154.066 1.00 67.49  ?  295 ILE B CD1 1 
ATOM   7552  N  N   . MET B 1 307 ? 130.147 183.449 158.117 1.00 68.17  ?  296 MET B N   1 
ATOM   7553  C  CA  . MET B 1 307 ? 129.356 182.759 159.125 1.00 68.17  ?  296 MET B CA  1 
ATOM   7554  C  C   . MET B 1 307 ? 130.181 182.458 160.365 1.00 68.17  ?  296 MET B C   1 
ATOM   7555  O  O   . MET B 1 307 ? 129.692 182.608 161.484 1.00 68.17  ?  296 MET B O   1 
ATOM   7556  C  CB  . MET B 1 307 ? 128.764 181.479 158.545 1.00 68.17  ?  296 MET B CB  1 
ATOM   7557  C  CG  . MET B 1 307 ? 127.395 181.667 157.919 1.00 68.17  ?  296 MET B CG  1 
ATOM   7558  S  SD  . MET B 1 307 ? 126.252 182.548 158.989 1.00 68.17  ?  296 MET B SD  1 
ATOM   7559  C  CE  . MET B 1 307 ? 126.088 184.079 158.091 1.00 68.17  ?  296 MET B CE  1 
ATOM   7560  N  N   . THR B 1 308 ? 131.439 182.095 160.173 1.00 64.11  ?  297 THR B N   1 
ATOM   7561  C  CA  . THR B 1 308 ? 132.335 181.794 161.277 1.00 64.11  ?  297 THR B CA  1 
ATOM   7562  C  C   . THR B 1 308 ? 132.641 183.030 162.099 1.00 64.11  ?  297 THR B C   1 
ATOM   7563  O  O   . THR B 1 308 ? 132.691 182.966 163.311 1.00 64.11  ?  297 THR B O   1 
ATOM   7564  C  CB  . THR B 1 308 ? 133.641 181.182 160.769 1.00 64.11  ?  297 THR B CB  1 
ATOM   7565  O  OG1 . THR B 1 308 ? 133.332 180.087 159.910 1.00 64.11  ?  297 THR B OG1 1 
ATOM   7566  C  CG2 . THR B 1 308 ? 134.477 180.678 161.915 1.00 64.11  ?  297 THR B CG2 1 
ATOM   7567  N  N   . VAL B 1 309 ? 132.861 184.154 161.434 1.00 63.78  ?  298 VAL B N   1 
ATOM   7568  C  CA  . VAL B 1 309 ? 133.143 185.407 162.128 1.00 63.78  ?  298 VAL B CA  1 
ATOM   7569  C  C   . VAL B 1 309 ? 131.915 185.883 162.892 1.00 63.78  ?  298 VAL B C   1 
ATOM   7570  O  O   . VAL B 1 309 ? 132.006 186.272 164.060 1.00 63.78  ?  298 VAL B O   1 
ATOM   7571  C  CB  . VAL B 1 309 ? 133.652 186.475 161.144 1.00 63.78  ?  298 VAL B CB  1 
ATOM   7572  C  CG1 . VAL B 1 309 ? 133.916 187.765 161.874 1.00 63.78  ?  298 VAL B CG1 1 
ATOM   7573  C  CG2 . VAL B 1 309 ? 134.925 186.009 160.496 1.00 63.78  ?  298 VAL B CG2 1 
ATOM   7574  N  N   . ILE B 1 310 ? 130.764 185.910 162.240 1.00 65.10  ?  299 ILE B N   1 
ATOM   7575  C  CA  . ILE B 1 310 ? 129.543 186.331 162.916 1.00 65.10  ?  299 ILE B CA  1 
ATOM   7576  C  C   . ILE B 1 310 ? 129.205 185.396 164.064 1.00 65.10  ?  299 ILE B C   1 
ATOM   7577  O  O   . ILE B 1 310 ? 128.831 185.840 165.145 1.00 65.10  ?  299 ILE B O   1 
ATOM   7578  C  CB  . ILE B 1 310 ? 128.349 186.383 161.951 1.00 65.10  ?  299 ILE B CB  1 
ATOM   7579  C  CG1 . ILE B 1 310 ? 128.621 187.378 160.824 1.00 65.10  ?  299 ILE B CG1 1 
ATOM   7580  C  CG2 . ILE B 1 310 ? 127.078 186.759 162.694 1.00 65.10  ?  299 ILE B CG2 1 
ATOM   7581  C  CD1 . ILE B 1 310 ? 127.495 187.478 159.822 1.00 65.10  ?  299 ILE B CD1 1 
ATOM   7582  N  N   . ALA B 1 311 ? 129.345 184.099 163.838 1.00 64.98  ?  300 ALA B N   1 
ATOM   7583  C  CA  . ALA B 1 311 ? 129.005 183.132 164.866 1.00 64.98  ?  300 ALA B CA  1 
ATOM   7584  C  C   . ALA B 1 311 ? 129.855 183.321 166.101 1.00 64.98  ?  300 ALA B C   1 
ATOM   7585  O  O   . ALA B 1 311 ? 129.337 183.372 167.212 1.00 64.98  ?  300 ALA B O   1 
ATOM   7586  C  CB  . ALA B 1 311 ? 129.173 181.724 164.327 1.00 64.98  ?  300 ALA B CB  1 
ATOM   7587  N  N   . ALA B 1 312 ? 131.160 183.437 165.915 1.00 62.75  ?  301 ALA B N   1 
ATOM   7588  C  CA  . ALA B 1 312 ? 132.057 183.583 167.045 1.00 62.75  ?  301 ALA B CA  1 
ATOM   7589  C  C   . ALA B 1 312 ? 131.792 184.882 167.770 1.00 62.75  ?  301 ALA B C   1 
ATOM   7590  O  O   . ALA B 1 312 ? 131.868 184.938 168.992 1.00 62.75  ?  301 ALA B O   1 
ATOM   7591  C  CB  . ALA B 1 312 ? 133.494 183.521 166.577 1.00 62.75  ?  301 ALA B CB  1 
ATOM   7592  N  N   . GLY B 1 313 ? 131.480 185.930 167.021 1.00 64.29  ?  302 GLY B N   1 
ATOM   7593  C  CA  . GLY B 1 313 ? 131.240 187.225 167.623 1.00 64.29  ?  302 GLY B CA  1 
ATOM   7594  C  C   . GLY B 1 313 ? 130.035 187.217 168.521 1.00 64.29  ?  302 GLY B C   1 
ATOM   7595  O  O   . GLY B 1 313 ? 130.101 187.686 169.652 1.00 64.29  ?  302 GLY B O   1 
ATOM   7596  N  N   . VAL B 1 314 ? 128.932 186.669 168.030 1.00 65.66  ?  303 VAL B N   1 
ATOM   7597  C  CA  . VAL B 1 314 ? 127.720 186.602 168.821 1.00 65.66  ?  303 VAL B CA  1 
ATOM   7598  C  C   . VAL B 1 314 ? 127.932 185.710 170.034 1.00 65.66  ?  303 VAL B C   1 
ATOM   7599  O  O   . VAL B 1 314 ? 127.470 186.024 171.126 1.00 65.66  ?  303 VAL B O   1 
ATOM   7600  C  CB  . VAL B 1 314 ? 126.545 186.083 167.984 1.00 65.66  ?  303 VAL B CB  1 
ATOM   7601  C  CG1 . VAL B 1 314 ? 125.291 185.970 168.836 1.00 65.66  ?  303 VAL B CG1 1 
ATOM   7602  C  CG2 . VAL B 1 314 ? 126.309 186.992 166.790 1.00 65.66  ?  303 VAL B CG2 1 
ATOM   7603  N  N   . SER B 1 315 ? 128.642 184.605 169.850 1.00 66.23  ?  304 SER B N   1 
ATOM   7604  C  CA  . SER B 1 315 ? 128.911 183.704 170.963 1.00 66.23  ?  304 SER B CA  1 
ATOM   7605  C  C   . SER B 1 315 ? 129.657 184.427 172.067 1.00 66.23  ?  304 SER B C   1 
ATOM   7606  O  O   . SER B 1 315 ? 129.322 184.289 173.238 1.00 66.23  ?  304 SER B O   1 
ATOM   7607  C  CB  . SER B 1 315 ? 129.721 182.498 170.496 1.00 66.23  ?  304 SER B CB  1 
ATOM   7608  O  OG  . SER B 1 315 ? 130.048 181.653 171.584 1.00 66.23  ?  304 SER B OG  1 
ATOM   7609  N  N   . TYR B 1 316 ? 130.673 185.195 171.700 1.00 67.65  ?  305 TYR B N   1 
ATOM   7610  C  CA  . TYR B 1 316 ? 131.439 185.948 172.682 1.00 67.65  ?  305 TYR B CA  1 
ATOM   7611  C  C   . TYR B 1 316 ? 130.637 187.109 173.249 1.00 67.65  ?  305 TYR B C   1 
ATOM   7612  O  O   . TYR B 1 316 ? 130.604 187.309 174.460 1.00 67.65  ?  305 TYR B O   1 
ATOM   7613  C  CB  . TYR B 1 316 ? 132.731 186.453 172.041 1.00 67.65  ?  305 TYR B CB  1 
ATOM   7614  C  CG  . TYR B 1 316 ? 133.620 187.259 172.951 1.00 67.65  ?  305 TYR B CG  1 
ATOM   7615  C  CD1 . TYR B 1 316 ? 133.694 188.638 172.834 1.00 67.65  ?  305 TYR B CD1 1 
ATOM   7616  C  CD2 . TYR B 1 316 ? 134.394 186.641 173.919 1.00 67.65  ?  305 TYR B CD2 1 
ATOM   7617  C  CE1 . TYR B 1 316 ? 134.511 189.382 173.660 1.00 67.65  ?  305 TYR B CE1 1 
ATOM   7618  C  CE2 . TYR B 1 316 ? 135.214 187.376 174.752 1.00 67.65  ?  305 TYR B CE2 1 
ATOM   7619  C  CZ  . TYR B 1 316 ? 135.268 188.745 174.617 1.00 67.65  ?  305 TYR B CZ  1 
ATOM   7620  O  OH  . TYR B 1 316 ? 136.083 189.482 175.444 1.00 67.65  ?  305 TYR B OH  1 
ATOM   7621  N  N   . GLY B 1 317 ? 130.047 187.878 172.344 1.00 69.81  ?  306 GLY B N   1 
ATOM   7622  C  CA  . GLY B 1 317 ? 129.252 189.038 172.680 1.00 69.81  ?  306 GLY B CA  1 
ATOM   7623  C  C   . GLY B 1 317 ? 128.097 188.709 173.584 1.00 69.81  ?  306 GLY B C   1 
ATOM   7624  O  O   . GLY B 1 317 ? 127.798 189.458 174.498 1.00 69.81  ?  306 GLY B O   1 
ATOM   7625  N  N   . CYS B 1 318 ? 127.416 187.612 173.300 1.00 72.80  ?  307 CYS B N   1 
ATOM   7626  C  CA  . CYS B 1 318 ? 126.267 187.218 174.090 1.00 72.80  ?  307 CYS B CA  1 
ATOM   7627  C  C   . CYS B 1 318 ? 126.619 186.152 175.108 1.00 72.80  ?  307 CYS B C   1 
ATOM   7628  O  O   . CYS B 1 318 ? 125.740 185.607 175.761 1.00 72.80  ?  307 CYS B O   1 
ATOM   7629  C  CB  . CYS B 1 318 ? 125.151 186.723 173.183 1.00 72.80  ?  307 CYS B CB  1 
ATOM   7630  S  SG  . CYS B 1 318 ? 124.793 187.795 171.781 1.00 72.80  ?  307 CYS B SG  1 
ATOM   7631  N  N   . ASP B 1 319 ? 127.907 185.855 175.225 1.00 73.85  ?  308 ASP B N   1 
ATOM   7632  C  CA  . ASP B 1 319 ? 128.399 184.867 176.173 1.00 73.85  ?  308 ASP B CA  1 
ATOM   7633  C  C   . ASP B 1 319 ? 127.664 183.551 176.060 1.00 73.85  ?  308 ASP B C   1 
ATOM   7634  O  O   . ASP B 1 319 ? 127.206 183.018 177.057 1.00 73.85  ?  308 ASP B O   1 
ATOM   7635  C  CB  . ASP B 1 319 ? 128.363 185.379 177.608 1.00 73.85  ?  308 ASP B CB  1 
ATOM   7636  C  CG  . ASP B 1 319 ? 129.356 184.661 178.501 1.00 73.85  ?  308 ASP B CG  1 
ATOM   7637  O  OD1 . ASP B 1 319 ? 130.125 183.823 177.985 1.00 73.85  ?  308 ASP B OD1 1 
ATOM   7638  O  OD2 . ASP B 1 319 ? 129.377 184.934 179.718 1.00 73.85  -1 308 ASP B OD2 1 
ATOM   7639  N  N   . PHE B 1 320 ? 127.597 183.002 174.854 1.00 69.60  ?  309 PHE B N   1 
ATOM   7640  C  CA  . PHE B 1 320 ? 126.867 181.766 174.589 1.00 69.60  ?  309 PHE B CA  1 
ATOM   7641  C  C   . PHE B 1 320 ? 127.353 180.585 175.411 1.00 69.60  ?  309 PHE B C   1 
ATOM   7642  O  O   . PHE B 1 320 ? 126.557 179.763 175.814 1.00 69.60  ?  309 PHE B O   1 
ATOM   7643  C  CB  . PHE B 1 320 ? 126.933 181.410 173.110 1.00 69.60  ?  309 PHE B CB  1 
ATOM   7644  C  CG  . PHE B 1 320 ? 125.868 182.053 172.278 1.00 69.60  ?  309 PHE B CG  1 
ATOM   7645  C  CD1 . PHE B 1 320 ? 125.137 183.113 172.758 1.00 69.60  ?  309 PHE B CD1 1 
ATOM   7646  C  CD2 . PHE B 1 320 ? 125.620 181.605 171.003 1.00 69.60  ?  309 PHE B CD2 1 
ATOM   7647  C  CE1 . PHE B 1 320 ? 124.164 183.704 171.986 1.00 69.60  ?  309 PHE B CE1 1 
ATOM   7648  C  CE2 . PHE B 1 320 ? 124.655 182.193 170.222 1.00 69.60  ?  309 PHE B CE2 1 
ATOM   7649  C  CZ  . PHE B 1 320 ? 123.925 183.249 170.713 1.00 69.60  ?  309 PHE B CZ  1 
ATOM   7650  N  N   . LYS B 1 321 ? 128.646 180.494 175.667 1.00 70.51  ?  310 LYS B N   1 
ATOM   7651  C  CA  . LYS B 1 321 ? 129.195 179.400 176.438 1.00 70.51  ?  310 LYS B CA  1 
ATOM   7652  C  C   . LYS B 1 321 ? 128.596 179.337 177.834 1.00 70.51  ?  310 LYS B C   1 
ATOM   7653  O  O   . LYS B 1 321 ? 128.380 178.260 178.352 1.00 70.51  ?  310 LYS B O   1 
ATOM   7654  C  CB  . LYS B 1 321 ? 130.700 179.590 176.571 1.00 70.51  ?  310 LYS B CB  1 
ATOM   7655  C  CG  . LYS B 1 321 ? 131.450 178.346 176.999 1.00 70.51  ?  310 LYS B CG  1 
ATOM   7656  C  CD  . LYS B 1 321 ? 132.705 178.712 177.766 1.00 70.51  ?  310 LYS B CD  1 
ATOM   7657  C  CE  . LYS B 1 321 ? 133.271 180.026 177.268 1.00 70.51  ?  310 LYS B CE  1 
ATOM   7658  N  NZ  . LYS B 1 321 ? 134.234 180.601 178.242 1.00 70.51  1  310 LYS B NZ  1 
ATOM   7659  N  N   . ASN B 1 322 ? 128.400 180.479 178.482 1.00 72.82  ?  311 ASN B N   1 
ATOM   7660  C  CA  . ASN B 1 322 ? 127.802 180.495 179.812 1.00 72.82  ?  311 ASN B CA  1 
ATOM   7661  C  C   . ASN B 1 322 ? 126.290 180.616 179.826 1.00 72.82  ?  311 ASN B C   1 
ATOM   7662  O  O   . ASN B 1 322 ? 125.622 179.986 180.626 1.00 72.82  ?  311 ASN B O   1 
ATOM   7663  C  CB  . ASN B 1 322 ? 128.408 181.609 180.652 1.00 72.82  ?  311 ASN B CB  1 
ATOM   7664  C  CG  . ASN B 1 322 ? 129.892 181.447 180.831 1.00 72.82  ?  311 ASN B CG  1 
ATOM   7665  O  OD1 . ASN B 1 322 ? 130.629 182.421 180.877 1.00 72.82  ?  311 ASN B OD1 1 
ATOM   7666  N  ND2 . ASN B 1 322 ? 130.340 180.205 180.920 1.00 72.82  ?  311 ASN B ND2 1 
ATOM   7667  N  N   . ARG B 1 323 ? 125.763 181.464 178.958 1.00 73.52  ?  312 ARG B N   1 
ATOM   7668  C  CA  . ARG B 1 323 ? 124.333 181.683 178.869 1.00 73.52  ?  312 ARG B CA  1 
ATOM   7669  C  C   . ARG B 1 323 ? 123.515 180.486 178.393 1.00 73.52  ?  312 ARG B C   1 
ATOM   7670  O  O   . ARG B 1 323 ? 122.483 180.166 178.963 1.00 73.52  ?  312 ARG B O   1 
ATOM   7671  C  CB  . ARG B 1 323 ? 124.074 182.879 177.966 1.00 73.52  ?  312 ARG B CB  1 
ATOM   7672  C  CG  . ARG B 1 323 ? 122.628 183.083 177.579 1.00 73.52  ?  312 ARG B CG  1 
ATOM   7673  C  CD  . ARG B 1 323 ? 122.433 184.493 177.075 1.00 73.52  ?  312 ARG B CD  1 
ATOM   7674  N  NE  . ARG B 1 323 ? 122.784 185.442 178.121 1.00 73.52  ?  312 ARG B NE  1 
ATOM   7675  C  CZ  . ARG B 1 323 ? 123.003 186.735 177.922 1.00 73.52  ?  312 ARG B CZ  1 
ATOM   7676  N  NH1 . ARG B 1 323 ? 123.314 187.510 178.946 1.00 73.52  1  312 ARG B NH1 1 
ATOM   7677  N  NH2 . ARG B 1 323 ? 122.914 187.251 176.704 1.00 73.52  ?  312 ARG B NH2 1 
ATOM   7678  N  N   . PHE B 1 324 ? 124.003 179.799 177.371 1.00 71.10  ?  313 PHE B N   1 
ATOM   7679  C  CA  . PHE B 1 324 ? 123.278 178.672 176.809 1.00 71.10  ?  313 PHE B CA  1 
ATOM   7680  C  C   . PHE B 1 324 ? 124.021 177.378 176.953 1.00 71.10  ?  313 PHE B C   1 
ATOM   7681  O  O   . PHE B 1 324 ? 123.628 176.391 176.358 1.00 71.10  ?  313 PHE B O   1 
ATOM   7682  C  CB  . PHE B 1 324 ? 122.990 178.900 175.330 1.00 71.10  ?  313 PHE B CB  1 
ATOM   7683  C  CG  . PHE B 1 324 ? 122.004 179.984 175.074 1.00 71.10  ?  313 PHE B CG  1 
ATOM   7684  C  CD1 . PHE B 1 324 ? 120.796 179.999 175.733 1.00 71.10  ?  313 PHE B CD1 1 
ATOM   7685  C  CD2 . PHE B 1 324 ? 122.278 180.982 174.166 1.00 71.10  ?  313 PHE B CD2 1 
ATOM   7686  C  CE1 . PHE B 1 324 ? 119.881 180.994 175.496 1.00 71.10  ?  313 PHE B CE1 1 
ATOM   7687  C  CE2 . PHE B 1 324 ? 121.368 181.981 173.922 1.00 71.10  ?  313 PHE B CE2 1 
ATOM   7688  C  CZ  . PHE B 1 324 ? 120.165 181.986 174.585 1.00 71.10  ?  313 PHE B CZ  1 
ATOM   7689  N  N   . LYS B 1 325 ? 125.101 177.405 177.720 1.00 69.80  ?  314 LYS B N   1 
ATOM   7690  C  CA  . LYS B 1 325 ? 125.924 176.224 177.974 1.00 69.80  ?  314 LYS B CA  1 
ATOM   7691  C  C   . LYS B 1 325 ? 126.305 175.524 176.680 1.00 69.80  ?  314 LYS B C   1 
ATOM   7692  O  O   . LYS B 1 325 ? 126.172 174.309 176.565 1.00 69.80  ?  314 LYS B O   1 
ATOM   7693  C  CB  . LYS B 1 325 ? 125.203 175.258 178.916 1.00 69.80  ?  314 LYS B CB  1 
ATOM   7694  C  CG  . LYS B 1 325 ? 124.949 175.815 180.309 1.00 69.80  ?  314 LYS B CG  1 
ATOM   7695  C  CD  . LYS B 1 325 ? 123.846 176.862 180.308 1.00 69.80  ?  314 LYS B CD  1 
ATOM   7696  C  CE  . LYS B 1 325 ? 123.745 177.576 181.645 1.00 69.80  ?  314 LYS B CE  1 
ATOM   7697  N  NZ  . LYS B 1 325 ? 122.793 178.719 181.580 1.00 69.80  1  314 LYS B NZ  1 
ATOM   7698  N  N   . VAL B 1 326 ? 126.781 176.287 175.708 1.00 65.73  ?  315 VAL B N   1 
ATOM   7699  C  CA  . VAL B 1 326 ? 127.146 175.718 174.418 1.00 65.73  ?  315 VAL B CA  1 
ATOM   7700  C  C   . VAL B 1 326 ? 128.580 175.227 174.418 1.00 65.73  ?  315 VAL B C   1 
ATOM   7701  O  O   . VAL B 1 326 ? 129.385 175.665 175.236 1.00 65.73  ?  315 VAL B O   1 
ATOM   7702  C  CB  . VAL B 1 326 ? 126.966 176.753 173.299 1.00 65.73  ?  315 VAL B CB  1 
ATOM   7703  C  CG1 . VAL B 1 326 ? 125.571 177.354 173.359 1.00 65.73  ?  315 VAL B CG1 1 
ATOM   7704  C  CG2 . VAL B 1 326 ? 128.018 177.845 173.409 1.00 65.73  ?  315 VAL B CG2 1 
ATOM   7705  N  N   . ALA B 1 327 ? 128.905 174.315 173.509 1.00 62.28  ?  316 ALA B N   1 
ATOM   7706  C  CA  . ALA B 1 327 ? 130.270 173.807 173.412 1.00 62.28  ?  316 ALA B CA  1 
ATOM   7707  C  C   . ALA B 1 327 ? 131.092 174.685 172.493 1.00 62.28  ?  316 ALA B C   1 
ATOM   7708  O  O   . ALA B 1 327 ? 130.776 174.818 171.315 1.00 62.28  ?  316 ALA B O   1 
ATOM   7709  C  CB  . ALA B 1 327 ? 130.274 172.376 172.921 1.00 62.28  ?  316 ALA B CB  1 
ATOM   7710  N  N   . VAL B 1 328 ? 132.146 175.287 173.024 1.00 60.37  ?  317 VAL B N   1 
ATOM   7711  C  CA  . VAL B 1 328 ? 132.972 176.182 172.236 1.00 60.37  ?  317 VAL B CA  1 
ATOM   7712  C  C   . VAL B 1 328 ? 134.319 175.546 171.936 1.00 60.37  ?  317 VAL B C   1 
ATOM   7713  O  O   . VAL B 1 328 ? 134.681 174.544 172.543 1.00 60.37  ?  317 VAL B O   1 
ATOM   7714  C  CB  . VAL B 1 328 ? 133.185 177.513 172.972 1.00 60.37  ?  317 VAL B CB  1 
ATOM   7715  C  CG1 . VAL B 1 328 ? 131.881 178.290 173.048 1.00 60.37  ?  317 VAL B CG1 1 
ATOM   7716  C  CG2 . VAL B 1 328 ? 133.755 177.268 174.358 1.00 60.37  ?  317 VAL B CG2 1 
ATOM   7717  N  N   . VAL B 1 329 ? 135.062 176.126 171.002 1.00 59.56  ?  318 VAL B N   1 
ATOM   7718  C  CA  . VAL B 1 329 ? 136.384 175.604 170.661 1.00 59.56  ?  318 VAL B CA  1 
ATOM   7719  C  C   . VAL B 1 329 ? 137.309 175.688 171.866 1.00 59.56  ?  318 VAL B C   1 
ATOM   7720  O  O   . VAL B 1 329 ? 138.129 174.794 172.104 1.00 59.56  ?  318 VAL B O   1 
ATOM   7721  C  CB  . VAL B 1 329 ? 136.950 176.352 169.441 1.00 59.56  ?  318 VAL B CB  1 
ATOM   7722  C  CG1 . VAL B 1 329 ? 138.460 176.359 169.455 1.00 59.56  ?  318 VAL B CG1 1 
ATOM   7723  C  CG2 . VAL B 1 329 ? 136.446 175.718 168.168 1.00 59.56  ?  318 VAL B CG2 1 
ATOM   7724  N  N   . GLY B 1 330 ? 137.177 176.737 172.652 1.00 62.70  ?  319 GLY B N   1 
ATOM   7725  C  CA  . GLY B 1 330 ? 137.918 176.843 173.883 1.00 62.70  ?  319 GLY B CA  1 
ATOM   7726  C  C   . GLY B 1 330 ? 139.300 177.416 173.686 1.00 62.70  ?  319 GLY B C   1 
ATOM   7727  O  O   . GLY B 1 330 ? 139.721 177.783 172.588 1.00 62.70  ?  319 GLY B O   1 
ATOM   7728  N  N   . ASP B 1 331 ? 140.024 177.483 174.793 1.00 67.37  ?  320 ASP B N   1 
ATOM   7729  C  CA  . ASP B 1 331 ? 141.361 178.054 174.795 1.00 67.37  ?  320 ASP B CA  1 
ATOM   7730  C  C   . ASP B 1 331 ? 142.358 177.028 174.278 1.00 67.37  ?  320 ASP B C   1 
ATOM   7731  O  O   . ASP B 1 331 ? 142.499 175.947 174.856 1.00 67.37  ?  320 ASP B O   1 
ATOM   7732  C  CB  . ASP B 1 331 ? 141.741 178.505 176.200 1.00 67.37  ?  320 ASP B CB  1 
ATOM   7733  C  CG  . ASP B 1 331 ? 141.339 179.932 176.478 1.00 67.37  ?  320 ASP B CG  1 
ATOM   7734  O  OD1 . ASP B 1 331 ? 141.026 180.659 175.515 1.00 67.37  ?  320 ASP B OD1 1 
ATOM   7735  O  OD2 . ASP B 1 331 ? 141.336 180.332 177.658 1.00 67.37  -1 320 ASP B OD2 1 
ATOM   7736  N  N   . MET B 1 332 ? 143.036 177.361 173.188 1.00 65.70  ?  321 MET B N   1 
ATOM   7737  C  CA  . MET B 1 332 ? 144.174 176.597 172.707 1.00 65.70  ?  321 MET B CA  1 
ATOM   7738  C  C   . MET B 1 332 ? 145.441 177.269 173.201 1.00 65.70  ?  321 MET B C   1 
ATOM   7739  O  O   . MET B 1 332 ? 145.555 178.495 173.155 1.00 65.70  ?  321 MET B O   1 
ATOM   7740  C  CB  . MET B 1 332 ? 144.193 176.520 171.181 1.00 65.70  ?  321 MET B CB  1 
ATOM   7741  C  CG  . MET B 1 332 ? 142.911 176.029 170.561 1.00 65.70  ?  321 MET B CG  1 
ATOM   7742  S  SD  . MET B 1 332 ? 143.028 175.842 168.778 1.00 65.70  ?  321 MET B SD  1 
ATOM   7743  C  CE  . MET B 1 332 ? 142.505 177.459 168.236 1.00 65.70  ?  321 MET B CE  1 
ATOM   7744  N  N   . ASN B 1 333 ? 146.378 176.480 173.687 1.00 65.57  ?  322 ASN B N   1 
ATOM   7745  C  CA  . ASN B 1 333 ? 147.634 177.085 174.100 1.00 65.57  ?  322 ASN B CA  1 
ATOM   7746  C  C   . ASN B 1 333 ? 148.478 177.389 172.870 1.00 65.57  ?  322 ASN B C   1 
ATOM   7747  O  O   . ASN B 1 333 ? 148.575 176.551 171.970 1.00 65.57  ?  322 ASN B O   1 
ATOM   7748  C  CB  . ASN B 1 333 ? 148.397 176.191 175.076 1.00 65.57  ?  322 ASN B CB  1 
ATOM   7749  C  CG  . ASN B 1 333 ? 148.434 174.737 174.650 1.00 65.57  ?  322 ASN B CG  1 
ATOM   7750  O  OD1 . ASN B 1 333 ? 148.704 174.413 173.495 1.00 65.57  ?  322 ASN B OD1 1 
ATOM   7751  N  ND2 . ASN B 1 333 ? 148.165 173.845 175.597 1.00 65.57  ?  322 ASN B ND2 1 
ATOM   7752  N  N   . PRO B 1 334 ? 149.061 178.577 172.776 1.00 61.47  ?  323 PRO B N   1 
ATOM   7753  C  CA  . PRO B 1 334 ? 149.840 178.918 171.588 1.00 61.47  ?  323 PRO B CA  1 
ATOM   7754  C  C   . PRO B 1 334 ? 151.117 178.106 171.513 1.00 61.47  ?  323 PRO B C   1 
ATOM   7755  O  O   . PRO B 1 334 ? 151.683 177.694 172.526 1.00 61.47  ?  323 PRO B O   1 
ATOM   7756  C  CB  . PRO B 1 334 ? 150.138 180.407 171.775 1.00 61.47  ?  323 PRO B CB  1 
ATOM   7757  C  CG  . PRO B 1 334 ? 150.011 180.637 173.219 1.00 61.47  ?  323 PRO B CG  1 
ATOM   7758  C  CD  . PRO B 1 334 ? 148.961 179.705 173.710 1.00 61.47  ?  323 PRO B CD  1 
ATOM   7759  N  N   . GLY B 1 335 ? 151.561 177.865 170.292 1.00 53.24  ?  324 GLY B N   1 
ATOM   7760  C  CA  . GLY B 1 335 ? 152.816 177.189 170.060 1.00 53.24  ?  324 GLY B CA  1 
ATOM   7761  C  C   . GLY B 1 335 ? 152.626 175.755 169.617 1.00 53.24  ?  324 GLY B C   1 
ATOM   7762  O  O   . GLY B 1 335 ? 151.524 175.209 169.595 1.00 53.24  ?  324 GLY B O   1 
ATOM   7763  N  N   . PHE B 1 336 ? 153.740 175.145 169.256 1.00 52.80  ?  325 PHE B N   1 
ATOM   7764  C  CA  . PHE B 1 336 ? 153.748 173.771 168.797 1.00 52.80  ?  325 PHE B CA  1 
ATOM   7765  C  C   . PHE B 1 336 ? 154.105 172.832 169.939 1.00 52.80  ?  325 PHE B C   1 
ATOM   7766  O  O   . PHE B 1 336 ? 154.582 173.246 170.995 1.00 52.80  ?  325 PHE B O   1 
ATOM   7767  C  CB  . PHE B 1 336 ? 154.734 173.601 167.646 1.00 52.80  ?  325 PHE B CB  1 
ATOM   7768  C  CG  . PHE B 1 336 ? 154.355 174.354 166.412 1.00 52.80  ?  325 PHE B CG  1 
ATOM   7769  C  CD1 . PHE B 1 336 ? 153.548 173.776 165.458 1.00 52.80  ?  325 PHE B CD1 1 
ATOM   7770  C  CD2 . PHE B 1 336 ? 154.809 175.636 166.203 1.00 52.80  ?  325 PHE B CD2 1 
ATOM   7771  C  CE1 . PHE B 1 336 ? 153.200 174.460 164.325 1.00 52.80  ?  325 PHE B CE1 1 
ATOM   7772  C  CE2 . PHE B 1 336 ? 154.464 176.321 165.071 1.00 52.80  ?  325 PHE B CE2 1 
ATOM   7773  C  CZ  . PHE B 1 336 ? 153.659 175.732 164.131 1.00 52.80  ?  325 PHE B CZ  1 
ATOM   7774  N  N   . GLN B 1 337 ? 153.866 171.633 169.732 1.00 55.37  ?  326 GLN B N   1 
ATOM   7775  C  CA  . GLN B 1 337 ? 154.233 170.659 170.739 1.00 55.37  ?  326 GLN B CA  1 
ATOM   7776  C  C   . GLN B 1 337 ? 155.643 170.149 170.480 1.00 55.37  ?  326 GLN B C   1 
ATOM   7777  O  O   . GLN B 1 337 ? 156.113 170.164 169.341 1.00 55.37  ?  326 GLN B O   1 
ATOM   7778  C  CB  . GLN B 1 337 ? 153.263 169.485 170.725 1.00 55.37  ?  326 GLN B CB  1 
ATOM   7779  C  CG  . GLN B 1 337 ? 151.818 169.860 170.897 1.00 55.37  ?  326 GLN B CG  1 
ATOM   7780  C  CD  . GLN B 1 337 ? 151.476 170.212 172.316 1.00 55.37  ?  326 GLN B CD  1 
ATOM   7781  O  OE1 . GLN B 1 337 ? 150.599 171.032 172.568 1.00 55.37  ?  326 GLN B OE1 1 
ATOM   7782  N  NE2 . GLN B 1 337 ? 152.164 169.592 173.258 1.00 55.37  ?  326 GLN B NE2 1 
ATOM   7783  N  N   . PRO B 1 338 ? 156.329 169.680 171.538 1.00 57.14  ?  327 PRO B N   1 
ATOM   7784  C  CA  . PRO B 1 338 ? 157.641 169.091 171.274 1.00 57.14  ?  327 PRO B CA  1 
ATOM   7785  C  C   . PRO B 1 338 ? 157.479 167.784 170.510 1.00 57.14  ?  327 PRO B C   1 
ATOM   7786  O  O   . PRO B 1 338 ? 156.426 167.157 170.589 1.00 57.14  ?  327 PRO B O   1 
ATOM   7787  C  CB  . PRO B 1 338 ? 158.187 168.813 172.673 1.00 57.14  ?  327 PRO B CB  1 
ATOM   7788  C  CG  . PRO B 1 338 ? 157.391 169.675 173.592 1.00 57.14  ?  327 PRO B CG  1 
ATOM   7789  C  CD  . PRO B 1 338 ? 156.030 169.719 172.980 1.00 57.14  ?  327 PRO B CD  1 
ATOM   7790  N  N   . PRO B 1 339 ? 158.518 167.375 169.774 1.00 56.62  ?  328 PRO B N   1 
ATOM   7791  C  CA  . PRO B 1 339 ? 158.436 166.135 169.004 1.00 56.62  ?  328 PRO B CA  1 
ATOM   7792  C  C   . PRO B 1 339 ? 158.139 164.952 169.906 1.00 56.62  ?  328 PRO B C   1 
ATOM   7793  O  O   . PRO B 1 339 ? 158.722 164.845 170.979 1.00 56.62  ?  328 PRO B O   1 
ATOM   7794  C  CB  . PRO B 1 339 ? 159.832 166.002 168.408 1.00 56.62  ?  328 PRO B CB  1 
ATOM   7795  C  CG  . PRO B 1 339 ? 160.374 167.388 168.383 1.00 56.62  ?  328 PRO B CG  1 
ATOM   7796  C  CD  . PRO B 1 339 ? 159.803 168.065 169.589 1.00 56.62  ?  328 PRO B CD  1 
ATOM   7797  N  N   . ILE B 1 340 ? 157.242 164.076 169.482 1.00 59.00  ?  329 ILE B N   1 
ATOM   7798  C  CA  . ILE B 1 340 ? 156.884 162.915 170.274 1.00 59.00  ?  329 ILE B CA  1 
ATOM   7799  C  C   . ILE B 1 340 ? 157.405 161.673 169.587 1.00 59.00  ?  329 ILE B C   1 
ATOM   7800  O  O   . ILE B 1 340 ? 157.611 161.672 168.379 1.00 59.00  ?  329 ILE B O   1 
ATOM   7801  C  CB  . ILE B 1 340 ? 155.359 162.807 170.446 1.00 59.00  ?  329 ILE B CB  1 
ATOM   7802  C  CG1 . ILE B 1 340 ? 154.997 161.683 171.417 1.00 59.00  ?  329 ILE B CG1 1 
ATOM   7803  C  CG2 . ILE B 1 340 ? 154.683 162.585 169.101 1.00 59.00  ?  329 ILE B CG2 1 
ATOM   7804  C  CD1 . ILE B 1 340 ? 153.507 161.461 171.553 1.00 59.00  ?  329 ILE B CD1 1 
ATOM   7805  N  N   . THR B 1 341 ? 157.627 160.612 170.350 1.00 63.05  ?  330 THR B N   1 
ATOM   7806  C  CA  . THR B 1 341 ? 158.161 159.382 169.781 1.00 63.05  ?  330 THR B CA  1 
ATOM   7807  C  C   . THR B 1 341 ? 157.054 158.419 169.426 1.00 63.05  ?  330 THR B C   1 
ATOM   7808  O  O   . THR B 1 341 ? 156.172 158.159 170.236 1.00 63.05  ?  330 THR B O   1 
ATOM   7809  C  CB  . THR B 1 341 ? 159.133 158.685 170.749 1.00 63.05  ?  330 THR B CB  1 
ATOM   7810  O  OG1 . THR B 1 341 ? 160.322 159.472 170.877 1.00 63.05  ?  330 THR B OG1 1 
ATOM   7811  C  CG2 . THR B 1 341 ? 159.503 157.304 170.238 1.00 63.05  ?  330 THR B CG2 1 
ATOM   7812  N  N   . PRO B 1 342 ? 157.095 157.886 168.204 1.00 63.67  ?  331 PRO B N   1 
ATOM   7813  C  CA  . PRO B 1 342 ? 156.081 156.923 167.776 1.00 63.67  ?  331 PRO B CA  1 
ATOM   7814  C  C   . PRO B 1 342 ? 156.021 155.731 168.717 1.00 63.67  ?  331 PRO B C   1 
ATOM   7815  O  O   . PRO B 1 342 ? 157.049 155.326 169.248 1.00 63.67  ?  331 PRO B O   1 
ATOM   7816  C  CB  . PRO B 1 342 ? 156.586 156.488 166.403 1.00 63.67  ?  331 PRO B CB  1 
ATOM   7817  C  CG  . PRO B 1 342 ? 157.359 157.658 165.903 1.00 63.67  ?  331 PRO B CG  1 
ATOM   7818  C  CD  . PRO B 1 342 ? 158.016 158.249 167.114 1.00 63.67  ?  331 PRO B CD  1 
ATOM   7819  N  N   . ASP B 1 343 ? 154.834 155.181 168.930 1.00 66.02  ?  332 ASP B N   1 
ATOM   7820  C  CA  . ASP B 1 343 ? 154.682 154.046 169.826 1.00 66.02  ?  332 ASP B CA  1 
ATOM   7821  C  C   . ASP B 1 343 ? 154.547 152.764 169.033 1.00 66.02  ?  332 ASP B C   1 
ATOM   7822  O  O   . ASP B 1 343 ? 153.618 152.612 168.246 1.00 66.02  ?  332 ASP B O   1 
ATOM   7823  C  CB  . ASP B 1 343 ? 153.461 154.235 170.717 1.00 66.02  ?  332 ASP B CB  1 
ATOM   7824  C  CG  . ASP B 1 343 ? 153.499 155.534 171.489 1.00 66.02  ?  332 ASP B CG  1 
ATOM   7825  O  OD1 . ASP B 1 343 ? 152.470 155.893 172.097 1.00 66.02  ?  332 ASP B OD1 1 
ATOM   7826  O  OD2 . ASP B 1 343 ? 154.553 156.201 171.487 1.00 66.02  -1 332 ASP B OD2 1 
ATOM   7827  N  N   . VAL B 1 344 ? 155.465 151.834 169.242 1.00 65.61  ?  333 VAL B N   1 
ATOM   7828  C  CA  . VAL B 1 344 ? 155.446 150.585 168.491 1.00 65.61  ?  333 VAL B CA  1 
ATOM   7829  C  C   . VAL B 1 344 ? 154.235 149.734 168.835 1.00 65.61  ?  333 VAL B C   1 
ATOM   7830  O  O   . VAL B 1 344 ? 153.759 148.971 168.002 1.00 65.61  ?  333 VAL B O   1 
ATOM   7831  C  CB  . VAL B 1 344 ? 156.739 149.784 168.727 1.00 65.61  ?  333 VAL B CB  1 
ATOM   7832  C  CG1 . VAL B 1 344 ? 157.929 150.531 168.151 1.00 65.61  ?  333 VAL B CG1 1 
ATOM   7833  C  CG2 . VAL B 1 344 ? 156.936 149.520 170.211 1.00 65.61  ?  333 VAL B CG2 1 
ATOM   7834  N  N   . GLU B 1 345 ? 153.732 149.854 170.054 1.00 67.42  ?  334 GLU B N   1 
ATOM   7835  C  CA  . GLU B 1 345 ? 152.523 149.126 170.416 1.00 67.42  ?  334 GLU B CA  1 
ATOM   7836  C  C   . GLU B 1 345 ? 151.337 149.593 169.584 1.00 67.42  ?  334 GLU B C   1 
ATOM   7837  O  O   . GLU B 1 345 ? 150.542 148.775 169.102 1.00 67.42  ?  334 GLU B O   1 
ATOM   7838  C  CB  . GLU B 1 345 ? 152.238 149.295 171.904 1.00 67.42  ?  334 GLU B CB  1 
ATOM   7839  C  CG  . GLU B 1 345 ? 151.146 148.387 172.414 1.00 67.42  ?  334 GLU B CG  1 
ATOM   7840  C  CD  . GLU B 1 345 ? 150.583 148.850 173.731 1.00 67.42  ?  334 GLU B CD  1 
ATOM   7841  O  OE1 . GLU B 1 345 ? 150.660 150.062 174.014 1.00 67.42  ?  334 GLU B OE1 1 
ATOM   7842  O  OE2 . GLU B 1 345 ? 150.062 148.002 174.485 1.00 67.42  -1 334 GLU B OE2 1 
ATOM   7843  N  N   . THR B 1 346 ? 151.205 150.907 169.400 1.00 63.79  ?  335 THR B N   1 
ATOM   7844  C  CA  . THR B 1 346 ? 150.176 151.430 168.512 1.00 63.79  ?  335 THR B CA  1 
ATOM   7845  C  C   . THR B 1 346 ? 150.392 150.953 167.084 1.00 63.79  ?  335 THR B C   1 
ATOM   7846  O  O   . THR B 1 346 ? 149.424 150.664 166.373 1.00 63.79  ?  335 THR B O   1 
ATOM   7847  C  CB  . THR B 1 346 ? 150.157 152.954 168.574 1.00 63.79  ?  335 THR B CB  1 
ATOM   7848  O  OG1 . THR B 1 346 ? 150.067 153.374 169.939 1.00 63.79  ?  335 THR B OG1 1 
ATOM   7849  C  CG2 . THR B 1 346 ? 148.971 153.506 167.811 1.00 63.79  ?  335 THR B CG2 1 
ATOM   7850  N  N   . PHE B 1 347 ? 151.650 150.858 166.650 1.00 61.07  ?  336 PHE B N   1 
ATOM   7851  C  CA  . PHE B 1 347 ? 151.940 150.302 165.333 1.00 61.07  ?  336 PHE B CA  1 
ATOM   7852  C  C   . PHE B 1 347 ? 151.382 148.895 165.205 1.00 61.07  ?  336 PHE B C   1 
ATOM   7853  O  O   . PHE B 1 347 ? 150.661 148.581 164.249 1.00 61.07  ?  336 PHE B O   1 
ATOM   7854  C  CB  . PHE B 1 347 ? 153.447 150.283 165.082 1.00 61.07  ?  336 PHE B CB  1 
ATOM   7855  C  CG  . PHE B 1 347 ? 154.032 151.615 164.729 1.00 61.07  ?  336 PHE B CG  1 
ATOM   7856  C  CD1 . PHE B 1 347 ? 153.386 152.788 165.049 1.00 61.07  ?  336 PHE B CD1 1 
ATOM   7857  C  CD2 . PHE B 1 347 ? 155.245 151.689 164.083 1.00 61.07  ?  336 PHE B CD2 1 
ATOM   7858  C  CE1 . PHE B 1 347 ? 153.936 153.999 164.730 1.00 61.07  ?  336 PHE B CE1 1 
ATOM   7859  C  CE2 . PHE B 1 347 ? 155.795 152.903 163.762 1.00 61.07  ?  336 PHE B CE2 1 
ATOM   7860  C  CZ  . PHE B 1 347 ? 155.137 154.058 164.086 1.00 61.07  ?  336 PHE B CZ  1 
ATOM   7861  N  N   . GLN B 1 348 ? 151.719 148.028 166.165 1.00 65.82  ?  337 GLN B N   1 
ATOM   7862  C  CA  . GLN B 1 348 ? 151.223 146.657 166.144 1.00 65.82  ?  337 GLN B CA  1 
ATOM   7863  C  C   . GLN B 1 348 ? 149.706 146.620 166.116 1.00 65.82  ?  337 GLN B C   1 
ATOM   7864  O  O   . GLN B 1 348 ? 149.111 145.816 165.391 1.00 65.82  ?  337 GLN B O   1 
ATOM   7865  C  CB  . GLN B 1 348 ? 151.733 145.888 167.359 1.00 65.82  ?  337 GLN B CB  1 
ATOM   7866  C  CG  . GLN B 1 348 ? 153.235 145.843 167.500 1.00 65.82  ?  337 GLN B CG  1 
ATOM   7867  C  CD  . GLN B 1 348 ? 153.663 145.550 168.920 1.00 65.82  ?  337 GLN B CD  1 
ATOM   7868  O  OE1 . GLN B 1 348 ? 154.841 145.651 169.258 1.00 65.82  ?  337 GLN B OE1 1 
ATOM   7869  N  NE2 . GLN B 1 348 ? 152.705 145.186 169.762 1.00 65.82  ?  337 GLN B NE2 1 
ATOM   7870  N  N   . ASN B 1 349 ? 149.061 147.480 166.895 1.00 64.75  ?  338 ASN B N   1 
ATOM   7871  C  CA  . ASN B 1 349 ? 147.614 147.411 167.003 1.00 64.75  ?  338 ASN B CA  1 
ATOM   7872  C  C   . ASN B 1 349 ? 146.888 148.048 165.825 1.00 64.75  ?  338 ASN B C   1 
ATOM   7873  O  O   . ASN B 1 349 ? 145.699 147.775 165.639 1.00 64.75  ?  338 ASN B O   1 
ATOM   7874  C  CB  . ASN B 1 349 ? 147.159 148.069 168.302 1.00 64.75  ?  338 ASN B CB  1 
ATOM   7875  C  CG  . ASN B 1 349 ? 147.602 147.300 169.523 1.00 64.75  ?  338 ASN B CG  1 
ATOM   7876  O  OD1 . ASN B 1 349 ? 147.657 146.073 169.505 1.00 64.75  ?  338 ASN B OD1 1 
ATOM   7877  N  ND2 . ASN B 1 349 ? 147.923 148.015 170.591 1.00 64.75  ?  338 ASN B ND2 1 
ATOM   7878  N  N   . THR B 1 350 ? 147.555 148.883 165.026 1.00 60.60  ?  339 THR B N   1 
ATOM   7879  C  CA  . THR B 1 350 ? 146.857 149.626 163.988 1.00 60.60  ?  339 THR B CA  1 
ATOM   7880  C  C   . THR B 1 350 ? 147.384 149.439 162.574 1.00 60.60  ?  339 THR B C   1 
ATOM   7881  O  O   . THR B 1 350 ? 146.864 150.098 161.674 1.00 60.60  ?  339 THR B O   1 
ATOM   7882  C  CB  . THR B 1 350 ? 146.877 151.124 164.310 1.00 60.60  ?  339 THR B CB  1 
ATOM   7883  O  OG1 . THR B 1 350 ? 148.192 151.505 164.719 1.00 60.60  ?  339 THR B OG1 1 
ATOM   7884  C  CG2 . THR B 1 350 ? 145.901 151.441 165.417 1.00 60.60  ?  339 THR B CG2 1 
ATOM   7885  N  N   . VAL B 1 351 ? 148.366 148.560 162.346 1.00 58.50  ?  340 VAL B N   1 
ATOM   7886  C  CA  . VAL B 1 351 ? 148.984 148.421 161.022 1.00 58.50  ?  340 VAL B CA  1 
ATOM   7887  C  C   . VAL B 1 351 ? 147.953 148.317 159.892 1.00 58.50  ?  340 VAL B C   1 
ATOM   7888  O  O   . VAL B 1 351 ? 148.144 148.886 158.807 1.00 58.50  ?  340 VAL B O   1 
ATOM   7889  C  CB  . VAL B 1 351 ? 149.958 147.226 161.026 1.00 58.50  ?  340 VAL B CB  1 
ATOM   7890  C  CG1 . VAL B 1 351 ? 149.234 145.945 161.348 1.00 58.50  ?  340 VAL B CG1 1 
ATOM   7891  C  CG2 . VAL B 1 351 ? 150.673 147.114 159.697 1.00 58.50  ?  340 VAL B CG2 1 
ATOM   7892  N  N   . GLY B 1 352 ? 146.839 147.620 160.119 1.00 56.36  ?  341 GLY B N   1 
ATOM   7893  C  CA  . GLY B 1 352 ? 145.858 147.466 159.051 1.00 56.36  ?  341 GLY B CA  1 
ATOM   7894  C  C   . GLY B 1 352 ? 145.096 148.747 158.758 1.00 56.36  ?  341 GLY B C   1 
ATOM   7895  O  O   . GLY B 1 352 ? 144.910 149.127 157.594 1.00 56.36  ?  341 GLY B O   1 
ATOM   7896  N  N   . ASP B 1 353 ? 144.638 149.428 159.808 1.00 56.88  ?  342 ASP B N   1 
ATOM   7897  C  CA  . ASP B 1 353 ? 144.020 150.733 159.631 1.00 56.88  ?  342 ASP B CA  1 
ATOM   7898  C  C   . ASP B 1 353 ? 144.982 151.704 158.975 1.00 56.88  ?  342 ASP B C   1 
ATOM   7899  O  O   . ASP B 1 353 ? 144.570 152.564 158.198 1.00 56.88  ?  342 ASP B O   1 
ATOM   7900  C  CB  . ASP B 1 353 ? 143.561 151.281 160.976 1.00 56.88  ?  342 ASP B CB  1 
ATOM   7901  C  CG  . ASP B 1 353 ? 142.868 150.246 161.812 1.00 56.88  ?  342 ASP B CG  1 
ATOM   7902  O  OD1 . ASP B 1 353 ? 142.725 150.465 163.031 1.00 56.88  ?  342 ASP B OD1 1 
ATOM   7903  O  OD2 . ASP B 1 353 ? 142.472 149.204 161.254 1.00 56.88  -1 342 ASP B OD2 1 
ATOM   7904  N  N   . CYS B 1 354 ? 146.270 151.581 159.281 1.00 53.37  ?  343 CYS B N   1 
ATOM   7905  C  CA  . CYS B 1 354 ? 147.251 152.493 158.711 1.00 53.37  ?  343 CYS B CA  1 
ATOM   7906  C  C   . CYS B 1 354 ? 147.462 152.215 157.232 1.00 53.37  ?  343 CYS B C   1 
ATOM   7907  O  O   . CYS B 1 354 ? 147.669 153.144 156.449 1.00 53.37  ?  343 CYS B O   1 
ATOM   7908  C  CB  . CYS B 1 354 ? 148.559 152.395 159.484 1.00 53.37  ?  343 CYS B CB  1 
ATOM   7909  S  SG  . CYS B 1 354 ? 148.457 153.090 161.133 1.00 53.37  ?  343 CYS B SG  1 
ATOM   7910  N  N   . PHE B 1 355 ? 147.401 150.948 156.825 1.00 51.99  ?  344 PHE B N   1 
ATOM   7911  C  CA  . PHE B 1 355 ? 147.428 150.641 155.398 1.00 51.99  ?  344 PHE B CA  1 
ATOM   7912  C  C   . PHE B 1 355 ? 146.224 151.247 154.691 1.00 51.99  ?  344 PHE B C   1 
ATOM   7913  O  O   . PHE B 1 355 ? 146.353 151.860 153.623 1.00 51.99  ?  344 PHE B O   1 
ATOM   7914  C  CB  . PHE B 1 355 ? 147.477 149.131 155.181 1.00 51.99  ?  344 PHE B CB  1 
ATOM   7915  C  CG  . PHE B 1 355 ? 148.853 148.608 154.947 1.00 51.99  ?  344 PHE B CG  1 
ATOM   7916  C  CD1 . PHE B 1 355 ? 149.446 148.716 153.706 1.00 51.99  ?  344 PHE B CD1 1 
ATOM   7917  C  CD2 . PHE B 1 355 ? 149.565 148.022 155.974 1.00 51.99  ?  344 PHE B CD2 1 
ATOM   7918  C  CE1 . PHE B 1 355 ? 150.718 148.241 153.496 1.00 51.99  ?  344 PHE B CE1 1 
ATOM   7919  C  CE2 . PHE B 1 355 ? 150.837 147.549 155.768 1.00 51.99  ?  344 PHE B CE2 1 
ATOM   7920  C  CZ  . PHE B 1 355 ? 151.414 147.657 154.529 1.00 51.99  ?  344 PHE B CZ  1 
ATOM   7921  N  N   . GLY B 1 356 ? 145.041 151.092 155.282 1.00 49.35  ?  345 GLY B N   1 
ATOM   7922  C  CA  . GLY B 1 356 ? 143.856 151.700 154.696 1.00 49.35  ?  345 GLY B CA  1 
ATOM   7923  C  C   . GLY B 1 356 ? 143.945 153.212 154.618 1.00 49.35  ?  345 GLY B C   1 
ATOM   7924  O  O   . GLY B 1 356 ? 143.548 153.817 153.621 1.00 49.35  ?  345 GLY B O   1 
ATOM   7925  N  N   . ILE B 1 357 ? 144.475 153.839 155.666 1.00 47.05  ?  346 ILE B N   1 
ATOM   7926  C  CA  . ILE B 1 357 ? 144.605 155.291 155.703 1.00 47.05  ?  346 ILE B CA  1 
ATOM   7927  C  C   . ILE B 1 357 ? 145.587 155.769 154.646 1.00 47.05  ?  346 ILE B C   1 
ATOM   7928  O  O   . ILE B 1 357 ? 145.332 156.750 153.944 1.00 47.05  ?  346 ILE B O   1 
ATOM   7929  C  CB  . ILE B 1 357 ? 145.023 155.748 157.111 1.00 47.05  ?  346 ILE B CB  1 
ATOM   7930  C  CG1 . ILE B 1 357 ? 143.840 155.681 158.069 1.00 47.05  ?  346 ILE B CG1 1 
ATOM   7931  C  CG2 . ILE B 1 357 ? 145.582 157.144 157.076 1.00 47.05  ?  346 ILE B CG2 1 
ATOM   7932  C  CD1 . ILE B 1 357 ? 144.236 155.678 159.505 1.00 47.05  ?  346 ILE B CD1 1 
ATOM   7933  N  N   . ALA B 1 358 ? 146.722 155.084 154.514 1.00 46.65  ?  347 ALA B N   1 
ATOM   7934  C  CA  . ALA B 1 358 ? 147.700 155.443 153.495 1.00 46.65  ?  347 ALA B CA  1 
ATOM   7935  C  C   . ALA B 1 358 ? 147.102 155.344 152.101 1.00 46.65  ?  347 ALA B C   1 
ATOM   7936  O  O   . ALA B 1 358 ? 147.273 156.246 151.271 1.00 46.65  ?  347 ALA B O   1 
ATOM   7937  C  CB  . ALA B 1 358 ? 148.926 154.545 153.618 1.00 46.65  ?  347 ALA B CB  1 
ATOM   7938  N  N   . MET B 1 359 ? 146.377 154.259 151.829 1.00 49.58  ?  348 MET B N   1 
ATOM   7939  C  CA  . MET B 1 359 ? 145.809 154.086 150.499 1.00 49.58  ?  348 MET B CA  1 
ATOM   7940  C  C   . MET B 1 359 ? 144.740 155.129 150.204 1.00 49.58  ?  348 MET B C   1 
ATOM   7941  O  O   . MET B 1 359 ? 144.704 155.685 149.103 1.00 49.58  ?  348 MET B O   1 
ATOM   7942  C  CB  . MET B 1 359 ? 145.248 152.677 150.348 1.00 49.58  ?  348 MET B CB  1 
ATOM   7943  C  CG  . MET B 1 359 ? 146.311 151.592 150.417 1.00 49.58  ?  348 MET B CG  1 
ATOM   7944  S  SD  . MET B 1 359 ? 147.496 151.618 149.054 1.00 49.58  ?  348 MET B SD  1 
ATOM   7945  C  CE  . MET B 1 359 ? 148.945 152.323 149.839 1.00 49.58  ?  348 MET B CE  1 
ATOM   7946  N  N   . VAL B 1 360 ? 143.869 155.423 151.170 1.00 45.88  ?  349 VAL B N   1 
ATOM   7947  C  CA  . VAL B 1 360 ? 142.824 156.409 150.928 1.00 45.88  ?  349 VAL B CA  1 
ATOM   7948  C  C   . VAL B 1 360 ? 143.424 157.795 150.745 1.00 45.88  ?  349 VAL B C   1 
ATOM   7949  O  O   . VAL B 1 360 ? 143.012 158.553 149.858 1.00 45.88  ?  349 VAL B O   1 
ATOM   7950  C  CB  . VAL B 1 360 ? 141.788 156.384 152.064 1.00 45.88  ?  349 VAL B CB  1 
ATOM   7951  C  CG1 . VAL B 1 360 ? 140.866 157.570 151.965 1.00 45.88  ?  349 VAL B CG1 1 
ATOM   7952  C  CG2 . VAL B 1 360 ? 140.988 155.119 152.004 1.00 45.88  ?  349 VAL B CG2 1 
ATOM   7953  N  N   . ALA B 1 361 ? 144.404 158.151 151.576 1.00 44.32  ?  350 ALA B N   1 
ATOM   7954  C  CA  . ALA B 1 361 ? 145.052 159.448 151.448 1.00 44.32  ?  350 ALA B CA  1 
ATOM   7955  C  C   . ALA B 1 361 ? 145.673 159.612 150.072 1.00 44.32  ?  350 ALA B C   1 
ATOM   7956  O  O   . ALA B 1 361 ? 145.460 160.628 149.399 1.00 44.32  ?  350 ALA B O   1 
ATOM   7957  C  CB  . ALA B 1 361 ? 146.103 159.614 152.539 1.00 44.32  ?  350 ALA B CB  1 
ATOM   7958  N  N   . PHE B 1 362 ? 146.430 158.607 149.624 1.00 45.22  ?  351 PHE B N   1 
ATOM   7959  C  CA  . PHE B 1 362 ? 147.067 158.719 148.320 1.00 45.22  ?  351 PHE B CA  1 
ATOM   7960  C  C   . PHE B 1 362 ? 146.041 158.761 147.198 1.00 45.22  ?  351 PHE B C   1 
ATOM   7961  O  O   . PHE B 1 362 ? 146.196 159.533 146.251 1.00 45.22  ?  351 PHE B O   1 
ATOM   7962  C  CB  . PHE B 1 362 ? 148.044 157.573 148.092 1.00 45.22  ?  351 PHE B CB  1 
ATOM   7963  C  CG  . PHE B 1 362 ? 148.651 157.579 146.725 1.00 45.22  ?  351 PHE B CG  1 
ATOM   7964  C  CD1 . PHE B 1 362 ? 149.326 158.693 146.262 1.00 45.22  ?  351 PHE B CD1 1 
ATOM   7965  C  CD2 . PHE B 1 362 ? 148.528 156.490 145.894 1.00 45.22  ?  351 PHE B CD2 1 
ATOM   7966  C  CE1 . PHE B 1 362 ? 149.871 158.710 145.008 1.00 45.22  ?  351 PHE B CE1 1 
ATOM   7967  C  CE2 . PHE B 1 362 ? 149.075 156.508 144.641 1.00 45.22  ?  351 PHE B CE2 1 
ATOM   7968  C  CZ  . PHE B 1 362 ? 149.745 157.617 144.198 1.00 45.22  ?  351 PHE B CZ  1 
ATOM   7969  N  N   . ALA B 1 363 ? 144.995 157.940 147.275 1.00 44.34  ?  352 ALA B N   1 
ATOM   7970  C  CA  . ALA B 1 363 ? 143.992 157.925 146.218 1.00 44.34  ?  352 ALA B CA  1 
ATOM   7971  C  C   . ALA B 1 363 ? 143.316 159.280 146.079 1.00 44.34  ?  352 ALA B C   1 
ATOM   7972  O  O   . ALA B 1 363 ? 143.170 159.802 144.968 1.00 44.34  ?  352 ALA B O   1 
ATOM   7973  C  CB  . ALA B 1 363 ? 142.960 156.838 146.494 1.00 44.34  ?  352 ALA B CB  1 
ATOM   7974  N  N   . VAL B 1 364 ? 142.905 159.874 147.199 1.00 43.73  ?  353 VAL B N   1 
ATOM   7975  C  CA  . VAL B 1 364 ? 142.242 161.173 147.146 1.00 43.73  ?  353 VAL B CA  1 
ATOM   7976  C  C   . VAL B 1 364 ? 143.185 162.233 146.596 1.00 43.73  ?  353 VAL B C   1 
ATOM   7977  O  O   . VAL B 1 364 ? 142.826 163.001 145.689 1.00 43.73  ?  353 VAL B O   1 
ATOM   7978  C  CB  . VAL B 1 364 ? 141.712 161.558 148.538 1.00 43.73  ?  353 VAL B CB  1 
ATOM   7979  C  CG1 . VAL B 1 364 ? 141.209 162.978 148.538 1.00 43.73  ?  353 VAL B CG1 1 
ATOM   7980  C  CG2 . VAL B 1 364 ? 140.617 160.617 148.954 1.00 43.73  ?  353 VAL B CG2 1 
ATOM   7981  N  N   . ALA B 1 365 ? 144.403 162.297 147.139 1.00 43.81  ?  354 ALA B N   1 
ATOM   7982  C  CA  . ALA B 1 365 ? 145.339 163.323 146.702 1.00 43.81  ?  354 ALA B CA  1 
ATOM   7983  C  C   . ALA B 1 365 ? 145.664 163.180 145.227 1.00 43.81  ?  354 ALA B C   1 
ATOM   7984  O  O   . ALA B 1 365 ? 145.730 164.177 144.503 1.00 43.81  ?  354 ALA B O   1 
ATOM   7985  C  CB  . ALA B 1 365 ? 146.610 163.267 147.539 1.00 43.81  ?  354 ALA B CB  1 
ATOM   7986  N  N   . PHE B 1 366 ? 145.846 161.947 144.755 1.00 45.64  ?  355 PHE B N   1 
ATOM   7987  C  CA  . PHE B 1 366 ? 146.196 161.738 143.361 1.00 45.64  ?  355 PHE B CA  1 
ATOM   7988  C  C   . PHE B 1 366 ? 145.031 162.043 142.435 1.00 45.64  ?  355 PHE B C   1 
ATOM   7989  O  O   . PHE B 1 366 ? 145.245 162.572 141.347 1.00 45.64  ?  355 PHE B O   1 
ATOM   7990  C  CB  . PHE B 1 366 ? 146.690 160.311 143.143 1.00 45.64  ?  355 PHE B CB  1 
ATOM   7991  C  CG  . PHE B 1 366 ? 147.351 160.107 141.819 1.00 45.64  ?  355 PHE B CG  1 
ATOM   7992  C  CD1 . PHE B 1 366 ? 146.702 159.442 140.801 1.00 45.64  ?  355 PHE B CD1 1 
ATOM   7993  C  CD2 . PHE B 1 366 ? 148.613 160.610 141.580 1.00 45.64  ?  355 PHE B CD2 1 
ATOM   7994  C  CE1 . PHE B 1 366 ? 147.305 159.271 139.583 1.00 45.64  ?  355 PHE B CE1 1 
ATOM   7995  C  CE2 . PHE B 1 366 ? 149.216 160.439 140.362 1.00 45.64  ?  355 PHE B CE2 1 
ATOM   7996  C  CZ  . PHE B 1 366 ? 148.562 159.770 139.365 1.00 45.64  ?  355 PHE B CZ  1 
ATOM   7997  N  N   . SER B 1 367 ? 143.798 161.754 142.848 1.00 45.80  ?  356 SER B N   1 
ATOM   7998  C  CA  . SER B 1 367 ? 142.652 162.109 142.020 1.00 45.80  ?  356 SER B CA  1 
ATOM   7999  C  C   . SER B 1 367 ? 142.538 163.617 141.852 1.00 45.80  ?  356 SER B C   1 
ATOM   8000  O  O   . SER B 1 367 ? 142.358 164.121 140.733 1.00 45.80  ?  356 SER B O   1 
ATOM   8001  C  CB  . SER B 1 367 ? 141.376 161.542 142.628 1.00 45.80  ?  356 SER B CB  1 
ATOM   8002  O  OG  . SER B 1 367 ? 141.412 160.133 142.637 1.00 45.80  ?  356 SER B OG  1 
ATOM   8003  N  N   . VAL B 1 368 ? 142.647 164.359 142.954 1.00 44.95  ?  357 VAL B N   1 
ATOM   8004  C  CA  . VAL B 1 368 ? 142.525 165.814 142.872 1.00 44.95  ?  357 VAL B CA  1 
ATOM   8005  C  C   . VAL B 1 368 ? 143.671 166.401 142.051 1.00 44.95  ?  357 VAL B C   1 
ATOM   8006  O  O   . VAL B 1 368 ? 143.472 167.245 141.159 1.00 44.95  ?  357 VAL B O   1 
ATOM   8007  C  CB  . VAL B 1 368 ? 142.460 166.415 144.285 1.00 44.95  ?  357 VAL B CB  1 
ATOM   8008  C  CG1 . VAL B 1 368 ? 142.354 167.908 144.224 1.00 44.95  ?  357 VAL B CG1 1 
ATOM   8009  C  CG2 . VAL B 1 368 ? 141.285 165.838 145.038 1.00 44.95  ?  357 VAL B CG2 1 
ATOM   8010  N  N   . ALA B 1 369 ? 144.891 165.944 142.326 1.00 46.43  ?  358 ALA B N   1 
ATOM   8011  C  CA  . ALA B 1 369 ? 146.042 166.438 141.595 1.00 46.43  ?  358 ALA B CA  1 
ATOM   8012  C  C   . ALA B 1 369 ? 145.963 166.090 140.121 1.00 46.43  ?  358 ALA B C   1 
ATOM   8013  O  O   . ALA B 1 369 ? 146.441 166.858 139.290 1.00 46.43  ?  358 ALA B O   1 
ATOM   8014  C  CB  . ALA B 1 369 ? 147.319 165.882 142.213 1.00 46.43  ?  358 ALA B CB  1 
ATOM   8015  N  N   . SER B 1 370 ? 145.366 164.947 139.776 1.00 47.04  ?  359 SER B N   1 
ATOM   8016  C  CA  . SER B 1 370 ? 145.235 164.571 138.376 1.00 47.04  ?  359 SER B CA  1 
ATOM   8017  C  C   . SER B 1 370 ? 144.244 165.468 137.664 1.00 47.04  ?  359 SER B C   1 
ATOM   8018  O  O   . SER B 1 370 ? 144.475 165.865 136.520 1.00 47.04  ?  359 SER B O   1 
ATOM   8019  C  CB  . SER B 1 370 ? 144.808 163.115 138.260 1.00 47.04  ?  359 SER B CB  1 
ATOM   8020  O  OG  . SER B 1 370 ? 145.687 162.285 138.979 1.00 47.04  ?  359 SER B OG  1 
ATOM   8021  N  N   . VAL B 1 371 ? 143.138 165.804 138.327 1.00 45.85  ?  360 VAL B N   1 
ATOM   8022  C  CA  . VAL B 1 371 ? 142.229 166.805 137.773 1.00 45.85  ?  360 VAL B CA  1 
ATOM   8023  C  C   . VAL B 1 371 ? 143.004 168.058 137.396 1.00 45.85  ?  360 VAL B C   1 
ATOM   8024  O  O   . VAL B 1 371 ? 142.943 168.536 136.257 1.00 45.85  ?  360 VAL B O   1 
ATOM   8025  C  CB  . VAL B 1 371 ? 141.100 167.123 138.768 1.00 45.85  ?  360 VAL B CB  1 
ATOM   8026  C  CG1 . VAL B 1 371 ? 140.337 168.346 138.317 1.00 45.85  ?  360 VAL B CG1 1 
ATOM   8027  C  CG2 . VAL B 1 371 ? 140.174 165.950 138.905 1.00 45.85  ?  360 VAL B CG2 1 
ATOM   8028  N  N   . TYR B 1 372 ? 143.776 168.591 138.340 1.00 46.70  ?  361 TYR B N   1 
ATOM   8029  C  CA  . TYR B 1 372 ? 144.399 169.886 138.071 1.00 46.70  ?  361 TYR B CA  1 
ATOM   8030  C  C   . TYR B 1 372 ? 145.572 169.787 137.102 1.00 46.70  ?  361 TYR B C   1 
ATOM   8031  O  O   . TYR B 1 372 ? 145.816 170.722 136.335 1.00 46.70  ?  361 TYR B O   1 
ATOM   8032  C  CB  . TYR B 1 372 ? 144.817 170.547 139.377 1.00 46.70  ?  361 TYR B CB  1 
ATOM   8033  C  CG  . TYR B 1 372 ? 143.616 171.005 140.137 1.00 46.70  ?  361 TYR B CG  1 
ATOM   8034  C  CD1 . TYR B 1 372 ? 142.676 171.817 139.535 1.00 46.70  ?  361 TYR B CD1 1 
ATOM   8035  C  CD2 . TYR B 1 372 ? 143.388 170.588 141.433 1.00 46.70  ?  361 TYR B CD2 1 
ATOM   8036  C  CE1 . TYR B 1 372 ? 141.562 172.217 140.204 1.00 46.70  ?  361 TYR B CE1 1 
ATOM   8037  C  CE2 . TYR B 1 372 ? 142.271 170.992 142.112 1.00 46.70  ?  361 TYR B CE2 1 
ATOM   8038  C  CZ  . TYR B 1 372 ? 141.364 171.806 141.490 1.00 46.70  ?  361 TYR B CZ  1 
ATOM   8039  O  OH  . TYR B 1 372 ? 140.244 172.215 142.154 1.00 46.70  ?  361 TYR B OH  1 
ATOM   8040  N  N   . SER B 1 373 ? 146.293 168.669 137.099 1.00 49.68  ?  362 SER B N   1 
ATOM   8041  C  CA  . SER B 1 373 ? 147.416 168.521 136.185 1.00 49.68  ?  362 SER B CA  1 
ATOM   8042  C  C   . SER B 1 373 ? 146.945 168.289 134.763 1.00 49.68  ?  362 SER B C   1 
ATOM   8043  O  O   . SER B 1 373 ? 147.623 168.692 133.816 1.00 49.68  ?  362 SER B O   1 
ATOM   8044  C  CB  . SER B 1 373 ? 148.317 167.378 136.636 1.00 49.68  ?  362 SER B CB  1 
ATOM   8045  O  OG  . SER B 1 373 ? 147.750 166.132 136.304 1.00 49.68  ?  362 SER B OG  1 
ATOM   8046  N  N   . LEU B 1 374 ? 145.795 167.642 134.589 1.00 51.02  ?  363 LEU B N   1 
ATOM   8047  C  CA  . LEU B 1 374 ? 145.198 167.570 133.267 1.00 51.02  ?  363 LEU B CA  1 
ATOM   8048  C  C   . LEU B 1 374 ? 144.684 168.932 132.830 1.00 51.02  ?  363 LEU B C   1 
ATOM   8049  O  O   . LEU B 1 374 ? 144.823 169.306 131.663 1.00 51.02  ?  363 LEU B O   1 
ATOM   8050  C  CB  . LEU B 1 374 ? 144.075 166.540 133.263 1.00 51.02  ?  363 LEU B CB  1 
ATOM   8051  C  CG  . LEU B 1 374 ? 143.258 166.402 131.986 1.00 51.02  ?  363 LEU B CG  1 
ATOM   8052  C  CD1 . LEU B 1 374 ? 144.103 165.796 130.897 1.00 51.02  ?  363 LEU B CD1 1 
ATOM   8053  C  CD2 . LEU B 1 374 ? 142.041 165.554 132.249 1.00 51.02  ?  363 LEU B CD2 1 
ATOM   8054  N  N   . LYS B 1 375 ? 144.102 169.694 133.755 1.00 52.15  ?  364 LYS B N   1 
ATOM   8055  C  CA  . LYS B 1 375 ? 143.597 171.014 133.399 1.00 52.15  ?  364 LYS B CA  1 
ATOM   8056  C  C   . LYS B 1 375 ? 144.712 171.951 132.958 1.00 52.15  ?  364 LYS B C   1 
ATOM   8057  O  O   . LYS B 1 375 ? 144.528 172.741 132.030 1.00 52.15  ?  364 LYS B O   1 
ATOM   8058  C  CB  . LYS B 1 375 ? 142.836 171.613 134.574 1.00 52.15  ?  364 LYS B CB  1 
ATOM   8059  C  CG  . LYS B 1 375 ? 142.288 172.979 134.303 1.00 52.15  ?  364 LYS B CG  1 
ATOM   8060  C  CD  . LYS B 1 375 ? 141.480 173.464 135.467 1.00 52.15  ?  364 LYS B CD  1 
ATOM   8061  C  CE  . LYS B 1 375 ? 140.871 174.806 135.183 1.00 52.15  ?  364 LYS B CE  1 
ATOM   8062  N  NZ  . LYS B 1 375 ? 141.026 175.718 136.333 1.00 52.15  1  364 LYS B NZ  1 
ATOM   8063  N  N   . TYR B 1 376 ? 145.870 171.898 133.612 1.00 51.34  ?  365 TYR B N   1 
ATOM   8064  C  CA  . TYR B 1 376 ? 146.937 172.846 133.320 1.00 51.34  ?  365 TYR B CA  1 
ATOM   8065  C  C   . TYR B 1 376 ? 148.116 172.219 132.595 1.00 51.34  ?  365 TYR B C   1 
ATOM   8066  O  O   . TYR B 1 376 ? 149.125 172.893 132.385 1.00 51.34  ?  365 TYR B O   1 
ATOM   8067  C  CB  . TYR B 1 376 ? 147.403 173.527 134.604 1.00 51.34  ?  365 TYR B CB  1 
ATOM   8068  C  CG  . TYR B 1 376 ? 146.311 174.325 135.252 1.00 51.34  ?  365 TYR B CG  1 
ATOM   8069  C  CD1 . TYR B 1 376 ? 145.590 173.808 136.308 1.00 51.34  ?  365 TYR B CD1 1 
ATOM   8070  C  CD2 . TYR B 1 376 ? 145.976 175.581 134.786 1.00 51.34  ?  365 TYR B CD2 1 
ATOM   8071  C  CE1 . TYR B 1 376 ? 144.587 174.519 136.891 1.00 51.34  ?  365 TYR B CE1 1 
ATOM   8072  C  CE2 . TYR B 1 376 ? 144.968 176.301 135.367 1.00 51.34  ?  365 TYR B CE2 1 
ATOM   8073  C  CZ  . TYR B 1 376 ? 144.279 175.762 136.419 1.00 51.34  ?  365 TYR B CZ  1 
ATOM   8074  O  OH  . TYR B 1 376 ? 143.271 176.468 137.006 1.00 51.34  ?  365 TYR B OH  1 
ATOM   8075  N  N   . ASP B 1 377 ? 148.013 170.950 132.211 1.00 54.56  ?  366 ASP B N   1 
ATOM   8076  C  CA  . ASP B 1 377 ? 148.971 170.304 131.318 1.00 54.56  ?  366 ASP B CA  1 
ATOM   8077  C  C   . ASP B 1 377 ? 150.393 170.359 131.876 1.00 54.56  ?  366 ASP B C   1 
ATOM   8078  O  O   . ASP B 1 377 ? 151.290 170.980 131.309 1.00 54.56  ?  366 ASP B O   1 
ATOM   8079  C  CB  . ASP B 1 377 ? 148.900 170.927 129.922 1.00 54.56  ?  366 ASP B CB  1 
ATOM   8080  C  CG  . ASP B 1 377 ? 149.634 170.113 128.880 1.00 54.56  ?  366 ASP B CG  1 
ATOM   8081  O  OD1 . ASP B 1 377 ? 149.854 170.634 127.771 1.00 54.56  ?  366 ASP B OD1 1 
ATOM   8082  O  OD2 . ASP B 1 377 ? 149.990 168.954 129.162 1.00 54.56  -1 366 ASP B OD2 1 
ATOM   8083  N  N   . TYR B 1 378 ? 150.585 169.699 133.011 1.00 51.03  ?  367 TYR B N   1 
ATOM   8084  C  CA  . TYR B 1 378 ? 151.915 169.483 133.551 1.00 51.03  ?  367 TYR B CA  1 
ATOM   8085  C  C   . TYR B 1 378 ? 151.981 168.072 134.114 1.00 51.03  ?  367 TYR B C   1 
ATOM   8086  O  O   . TYR B 1 378 ? 150.958 167.522 134.525 1.00 51.03  ?  367 TYR B O   1 
ATOM   8087  C  CB  . TYR B 1 378 ? 152.292 170.512 134.631 1.00 51.03  ?  367 TYR B CB  1 
ATOM   8088  C  CG  . TYR B 1 378 ? 151.356 170.617 135.809 1.00 51.03  ?  367 TYR B CG  1 
ATOM   8089  C  CD1 . TYR B 1 378 ? 150.328 171.541 135.818 1.00 51.03  ?  367 TYR B CD1 1 
ATOM   8090  C  CD2 . TYR B 1 378 ? 151.521 169.818 136.924 1.00 51.03  ?  367 TYR B CD2 1 
ATOM   8091  C  CE1 . TYR B 1 378 ? 149.489 171.648 136.884 1.00 51.03  ?  367 TYR B CE1 1 
ATOM   8092  C  CE2 . TYR B 1 378 ? 150.681 169.920 137.993 1.00 51.03  ?  367 TYR B CE2 1 
ATOM   8093  C  CZ  . TYR B 1 378 ? 149.669 170.838 137.969 1.00 51.03  ?  367 TYR B CZ  1 
ATOM   8094  O  OH  . TYR B 1 378 ? 148.823 170.946 139.039 1.00 51.03  ?  367 TYR B OH  1 
ATOM   8095  N  N   . PRO B 1 379 ? 153.158 167.460 134.112 1.00 51.86  ?  368 PRO B N   1 
ATOM   8096  C  CA  . PRO B 1 379 ? 153.260 166.064 134.541 1.00 51.86  ?  368 PRO B CA  1 
ATOM   8097  C  C   . PRO B 1 379 ? 153.163 165.901 136.048 1.00 51.86  ?  368 PRO B C   1 
ATOM   8098  O  O   . PRO B 1 379 ? 153.651 166.718 136.830 1.00 51.86  ?  368 PRO B O   1 
ATOM   8099  C  CB  . PRO B 1 379 ? 154.643 165.647 134.032 1.00 51.86  ?  368 PRO B CB  1 
ATOM   8100  C  CG  . PRO B 1 379 ? 155.402 166.900 133.973 1.00 51.86  ?  368 PRO B CG  1 
ATOM   8101  C  CD  . PRO B 1 379 ? 154.436 167.967 133.595 1.00 51.86  ?  368 PRO B CD  1 
ATOM   8102  N  N   . LEU B 1 380 ? 152.537 164.803 136.446 1.00 51.16  ?  369 LEU B N   1 
ATOM   8103  C  CA  . LEU B 1 380 ? 152.276 164.489 137.843 1.00 51.16  ?  369 LEU B CA  1 
ATOM   8104  C  C   . LEU B 1 380 ? 152.859 163.116 138.141 1.00 51.16  ?  369 LEU B C   1 
ATOM   8105  O  O   . LEU B 1 380 ? 152.385 162.109 137.610 1.00 51.16  ?  369 LEU B O   1 
ATOM   8106  C  CB  . LEU B 1 380 ? 150.779 164.524 138.117 1.00 51.16  ?  369 LEU B CB  1 
ATOM   8107  C  CG  . LEU B 1 380 ? 150.315 164.557 139.559 1.00 51.16  ?  369 LEU B CG  1 
ATOM   8108  C  CD1 . LEU B 1 380 ? 150.384 165.968 140.083 1.00 51.16  ?  369 LEU B CD1 1 
ATOM   8109  C  CD2 . LEU B 1 380 ? 148.913 164.018 139.615 1.00 51.16  ?  369 LEU B CD2 1 
ATOM   8110  N  N   . ASP B 1 381 ? 153.883 163.075 138.984 1.00 53.65  ?  370 ASP B N   1 
ATOM   8111  C  CA  . ASP B 1 381 ? 154.576 161.834 139.302 1.00 53.65  ?  370 ASP B CA  1 
ATOM   8112  C  C   . ASP B 1 381 ? 153.942 161.184 140.524 1.00 53.65  ?  370 ASP B C   1 
ATOM   8113  O  O   . ASP B 1 381 ? 154.044 161.714 141.631 1.00 53.65  ?  370 ASP B O   1 
ATOM   8114  C  CB  . ASP B 1 381 ? 156.053 162.120 139.548 1.00 53.65  ?  370 ASP B CB  1 
ATOM   8115  C  CG  . ASP B 1 381 ? 156.881 160.867 139.656 1.00 53.65  ?  370 ASP B CG  1 
ATOM   8116  O  OD1 . ASP B 1 381 ? 156.339 159.770 139.428 1.00 53.65  ?  370 ASP B OD1 1 
ATOM   8117  O  OD2 . ASP B 1 381 ? 158.081 160.978 139.969 1.00 53.65  -1 370 ASP B OD2 1 
ATOM   8118  N  N   . GLY B 1 382 ? 153.306 160.028 140.331 1.00 50.01  ?  371 GLY B N   1 
ATOM   8119  C  CA  . GLY B 1 382 ? 152.601 159.392 141.432 1.00 50.01  ?  371 GLY B CA  1 
ATOM   8120  C  C   . GLY B 1 382 ? 153.526 158.866 142.511 1.00 50.01  ?  371 GLY B C   1 
ATOM   8121  O  O   . GLY B 1 382 ? 153.197 158.909 143.698 1.00 50.01  ?  371 GLY B O   1 
ATOM   8122  N  N   . ASN B 1 383 ? 154.695 158.368 142.118 1.00 50.99  ?  372 ASN B N   1 
ATOM   8123  C  CA  . ASN B 1 383 ? 155.656 157.886 143.101 1.00 50.99  ?  372 ASN B CA  1 
ATOM   8124  C  C   . ASN B 1 383 ? 156.202 159.027 143.940 1.00 50.99  ?  372 ASN B C   1 
ATOM   8125  O  O   . ASN B 1 383 ? 156.374 158.887 145.155 1.00 50.99  ?  372 ASN B O   1 
ATOM   8126  C  CB  . ASN B 1 383 ? 156.787 157.149 142.398 1.00 50.99  ?  372 ASN B CB  1 
ATOM   8127  C  CG  . ASN B 1 383 ? 156.298 155.979 141.602 1.00 50.99  ?  372 ASN B CG  1 
ATOM   8128  O  OD1 . ASN B 1 383 ? 155.521 155.175 142.089 1.00 50.99  ?  372 ASN B OD1 1 
ATOM   8129  N  ND2 . ASN B 1 383 ? 156.746 155.878 140.366 1.00 50.99  ?  372 ASN B ND2 1 
ATOM   8130  N  N   . GLN B 1 384 ? 156.488 160.138 143.280 1.00 52.10  ?  373 GLN B N   1 
ATOM   8131  C  CA  . GLN B 1 384 ? 156.981 161.306 143.957 1.00 52.10  ?  373 GLN B CA  1 
ATOM   8132  C  C   . GLN B 1 384 ? 155.888 161.783 144.880 1.00 52.10  ?  373 GLN B C   1 
ATOM   8133  O  O   . GLN B 1 384 ? 156.160 162.241 145.969 1.00 52.10  ?  373 GLN B O   1 
ATOM   8134  C  CB  . GLN B 1 384 ? 157.393 162.398 142.976 1.00 52.10  ?  373 GLN B CB  1 
ATOM   8135  C  CG  . GLN B 1 384 ? 158.147 163.545 143.628 1.00 52.10  ?  373 GLN B CG  1 
ATOM   8136  C  CD  . GLN B 1 384 ? 159.249 163.057 144.542 1.00 52.10  ?  373 GLN B CD  1 
ATOM   8137  O  OE1 . GLN B 1 384 ? 159.686 161.934 144.430 1.00 52.10  ?  373 GLN B OE1 1 
ATOM   8138  N  NE2 . GLN B 1 384 ? 159.686 163.893 145.450 1.00 52.10  ?  373 GLN B NE2 1 
ATOM   8139  N  N   . GLU B 1 385 ? 154.644 161.655 144.442 1.00 50.33  ?  374 GLU B N   1 
ATOM   8140  C  CA  . GLU B 1 385 ? 153.507 162.035 145.255 1.00 50.33  ?  374 GLU B CA  1 
ATOM   8141  C  C   . GLU B 1 385 ? 153.445 161.174 146.497 1.00 50.33  ?  374 GLU B C   1 
ATOM   8142  O  O   . GLU B 1 385 ? 153.144 161.665 147.559 1.00 50.33  ?  374 GLU B O   1 
ATOM   8143  C  CB  . GLU B 1 385 ? 152.205 161.899 144.476 1.00 50.33  ?  374 GLU B CB  1 
ATOM   8144  C  CG  . GLU B 1 385 ? 152.136 162.768 143.243 1.00 50.33  ?  374 GLU B CG  1 
ATOM   8145  C  CD  . GLU B 1 385 ? 152.218 164.233 143.583 1.00 50.33  ?  374 GLU B CD  1 
ATOM   8146  O  OE1 . GLU B 1 385 ? 151.223 164.762 144.104 1.00 50.33  ?  374 GLU B OE1 1 
ATOM   8147  O  OE2 . GLU B 1 385 ? 153.269 164.852 143.333 1.00 50.33  -1 374 GLU B OE2 1 
ATOM   8148  N  N   . LEU B 1 386 ? 153.713 159.884 146.359 1.00 46.74  ?  375 LEU B N   1 
ATOM   8149  C  CA  . LEU B 1 386 ? 153.699 158.988 147.496 1.00 46.74  ?  375 LEU B CA  1 
ATOM   8150  C  C   . LEU B 1 386 ? 154.794 159.331 148.485 1.00 46.74  ?  375 LEU B C   1 
ATOM   8151  O  O   . LEU B 1 386 ? 154.599 159.280 149.674 1.00 46.74  ?  375 LEU B O   1 
ATOM   8152  C  CB  . LEU B 1 386 ? 153.848 157.546 147.041 1.00 46.74  ?  375 LEU B CB  1 
ATOM   8153  C  CG  . LEU B 1 386 ? 152.568 156.802 146.704 1.00 46.74  ?  375 LEU B CG  1 
ATOM   8154  C  CD1 . LEU B 1 386 ? 152.849 155.538 145.926 1.00 46.74  ?  375 LEU B CD1 1 
ATOM   8155  C  CD2 . LEU B 1 386 ? 151.791 156.504 147.961 1.00 46.74  ?  375 LEU B CD2 1 
ATOM   8156  N  N   . ILE B 1 387 ? 155.952 159.688 147.973 1.00 46.92  ?  376 ILE B N   1 
ATOM   8157  C  CA  . ILE B 1 387 ? 157.099 160.059 148.800 1.00 46.92  ?  376 ILE B CA  1 
ATOM   8158  C  C   . ILE B 1 387 ? 156.812 161.338 149.579 1.00 46.92  ?  376 ILE B C   1 
ATOM   8159  O  O   . ILE B 1 387 ? 157.066 161.421 150.785 1.00 46.92  ?  376 ILE B O   1 
ATOM   8160  C  CB  . ILE B 1 387 ? 158.360 160.202 147.931 1.00 46.92  ?  376 ILE B CB  1 
ATOM   8161  C  CG1 . ILE B 1 387 ? 158.886 158.831 147.531 1.00 46.92  ?  376 ILE B CG1 1 
ATOM   8162  C  CG2 . ILE B 1 387 ? 159.434 160.966 148.665 1.00 46.92  ?  376 ILE B CG2 1 
ATOM   8163  C  CD1 . ILE B 1 387 ? 159.829 158.874 146.375 1.00 46.92  ?  376 ILE B CD1 1 
ATOM   8164  N  N   . ALA B 1 388 ? 156.273 162.351 148.900 1.00 45.43  ?  377 ALA B N   1 
ATOM   8165  C  CA  . ALA B 1 388 ? 156.031 163.640 149.537 1.00 45.43  ?  377 ALA B CA  1 
ATOM   8166  C  C   . ALA B 1 388 ? 154.954 163.543 150.603 1.00 45.43  ?  377 ALA B C   1 
ATOM   8167  O  O   . ALA B 1 388 ? 155.100 164.103 151.693 1.00 45.43  ?  377 ALA B O   1 
ATOM   8168  C  CB  . ALA B 1 388 ? 155.643 164.671 148.488 1.00 45.43  ?  377 ALA B CB  1 
ATOM   8169  N  N   . LEU B 1 389 ? 153.864 162.834 150.311 1.00 43.99  ?  378 LEU B N   1 
ATOM   8170  C  CA  . LEU B 1 389 ? 152.801 162.685 151.293 1.00 43.99  ?  378 LEU B CA  1 
ATOM   8171  C  C   . LEU B 1 389 ? 153.255 161.848 152.475 1.00 43.99  ?  378 LEU B C   1 
ATOM   8172  O  O   . LEU B 1 389 ? 152.881 162.132 153.614 1.00 43.99  ?  378 LEU B O   1 
ATOM   8173  C  CB  . LEU B 1 389 ? 151.568 162.073 150.642 1.00 43.99  ?  378 LEU B CB  1 
ATOM   8174  C  CG  . LEU B 1 389 ? 150.867 162.923 149.586 1.00 43.99  ?  378 LEU B CG  1 
ATOM   8175  C  CD1 . LEU B 1 389 ? 149.760 162.123 148.944 1.00 43.99  ?  378 LEU B CD1 1 
ATOM   8176  C  CD2 . LEU B 1 389 ? 150.332 164.211 150.172 1.00 43.99  ?  378 LEU B CD2 1 
ATOM   8177  N  N   . GLY B 1 390 ? 154.078 160.827 152.235 1.00 43.39  ?  379 GLY B N   1 
ATOM   8178  C  CA  . GLY B 1 390 ? 154.617 160.055 153.336 1.00 43.39  ?  379 GLY B CA  1 
ATOM   8179  C  C   . GLY B 1 390 ? 155.523 160.868 154.234 1.00 43.39  ?  379 GLY B C   1 
ATOM   8180  O  O   . GLY B 1 390 ? 155.425 160.785 155.457 1.00 43.39  ?  379 GLY B O   1 
ATOM   8181  N  N   . LEU B 1 391 ? 156.419 161.660 153.648 1.00 44.22  ?  380 LEU B N   1 
ATOM   8182  C  CA  . LEU B 1 391 ? 157.281 162.508 154.464 1.00 44.22  ?  380 LEU B CA  1 
ATOM   8183  C  C   . LEU B 1 391 ? 156.470 163.530 155.243 1.00 44.22  ?  380 LEU B C   1 
ATOM   8184  O  O   . LEU B 1 391 ? 156.750 163.791 156.419 1.00 44.22  ?  380 LEU B O   1 
ATOM   8185  C  CB  . LEU B 1 391 ? 158.317 163.206 153.590 1.00 44.22  ?  380 LEU B CB  1 
ATOM   8186  C  CG  . LEU B 1 391 ? 159.404 162.312 153.009 1.00 44.22  ?  380 LEU B CG  1 
ATOM   8187  C  CD1 . LEU B 1 391 ? 160.285 163.090 152.062 1.00 44.22  ?  380 LEU B CD1 1 
ATOM   8188  C  CD2 . LEU B 1 391 ? 160.218 161.696 154.121 1.00 44.22  ?  380 LEU B CD2 1 
ATOM   8189  N  N   . GLY B 1 392 ? 155.458 164.118 154.605 1.00 44.21  ?  381 GLY B N   1 
ATOM   8190  C  CA  . GLY B 1 392 ? 154.620 165.075 155.301 1.00 44.21  ?  381 GLY B CA  1 
ATOM   8191  C  C   . GLY B 1 392 ? 153.863 164.453 156.451 1.00 44.21  ?  381 GLY B C   1 
ATOM   8192  O  O   . GLY B 1 392 ? 153.751 165.047 157.521 1.00 44.21  ?  381 GLY B O   1 
ATOM   8193  N  N   . ASN B 1 393 ? 153.350 163.241 156.256 1.00 44.47  ?  382 ASN B N   1 
ATOM   8194  C  CA  . ASN B 1 393 ? 152.627 162.573 157.327 1.00 44.47  ?  382 ASN B CA  1 
ATOM   8195  C  C   . ASN B 1 393 ? 153.561 162.150 158.448 1.00 44.47  ?  382 ASN B C   1 
ATOM   8196  O  O   . ASN B 1 393 ? 153.188 162.211 159.619 1.00 44.47  ?  382 ASN B O   1 
ATOM   8197  C  CB  . ASN B 1 393 ? 151.863 161.376 156.780 1.00 44.47  ?  382 ASN B CB  1 
ATOM   8198  C  CG  . ASN B 1 393 ? 150.500 161.750 156.279 1.00 44.47  ?  382 ASN B CG  1 
ATOM   8199  O  OD1 . ASN B 1 393 ? 149.929 162.748 156.703 1.00 44.47  ?  382 ASN B OD1 1 
ATOM   8200  N  ND2 . ASN B 1 393 ? 149.966 160.957 155.370 1.00 44.47  ?  382 ASN B ND2 1 
ATOM   8201  N  N   . ILE B 1 394 ? 154.782 161.736 158.119 1.00 44.56  ?  383 ILE B N   1 
ATOM   8202  C  CA  . ILE B 1 394 ? 155.747 161.387 159.157 1.00 44.56  ?  383 ILE B CA  1 
ATOM   8203  C  C   . ILE B 1 394 ? 156.071 162.604 160.010 1.00 44.56  ?  383 ILE B C   1 
ATOM   8204  O  O   . ILE B 1 394 ? 156.055 162.539 161.242 1.00 44.56  ?  383 ILE B O   1 
ATOM   8205  C  CB  . ILE B 1 394 ? 157.016 160.783 158.534 1.00 44.56  ?  383 ILE B CB  1 
ATOM   8206  C  CG1 . ILE B 1 394 ? 156.747 159.372 158.027 1.00 44.56  ?  383 ILE B CG1 1 
ATOM   8207  C  CG2 . ILE B 1 394 ? 158.134 160.756 159.543 1.00 44.56  ?  383 ILE B CG2 1 
ATOM   8208  C  CD1 . ILE B 1 394 ? 157.776 158.875 157.061 1.00 44.56  ?  383 ILE B CD1 1 
ATOM   8209  N  N   . VAL B 1 395 ? 156.364 163.735 159.370 1.00 45.73  ?  384 VAL B N   1 
ATOM   8210  C  CA  . VAL B 1 395 ? 156.698 164.935 160.133 1.00 45.73  ?  384 VAL B CA  1 
ATOM   8211  C  C   . VAL B 1 395 ? 155.498 165.427 160.934 1.00 45.73  ?  384 VAL B C   1 
ATOM   8212  O  O   . VAL B 1 395 ? 155.635 165.820 162.102 1.00 45.73  ?  384 VAL B O   1 
ATOM   8213  C  CB  . VAL B 1 395 ? 157.240 166.020 159.188 1.00 45.73  ?  384 VAL B CB  1 
ATOM   8214  C  CG1 . VAL B 1 395 ? 157.489 167.299 159.934 1.00 45.73  ?  384 VAL B CG1 1 
ATOM   8215  C  CG2 . VAL B 1 395 ? 158.510 165.547 158.535 1.00 45.73  ?  384 VAL B CG2 1 
ATOM   8216  N  N   . CYS B 1 396 ? 154.307 165.397 160.339 1.00 47.95  ?  385 CYS B N   1 
ATOM   8217  C  CA  . CYS B 1 396 ? 153.103 165.806 161.046 1.00 47.95  ?  385 CYS B CA  1 
ATOM   8218  C  C   . CYS B 1 396 ? 152.856 164.934 162.268 1.00 47.95  ?  385 CYS B C   1 
ATOM   8219  O  O   . CYS B 1 396 ? 152.571 165.444 163.353 1.00 47.95  ?  385 CYS B O   1 
ATOM   8220  C  CB  . CYS B 1 396 ? 151.911 165.753 160.094 1.00 47.95  ?  385 CYS B CB  1 
ATOM   8221  S  SG  . CYS B 1 396 ? 150.406 166.433 160.742 1.00 47.95  ?  385 CYS B SG  1 
ATOM   8222  N  N   . GLY B 1 397 ? 152.954 163.616 162.111 1.00 48.47  ?  386 GLY B N   1 
ATOM   8223  C  CA  . GLY B 1 397 ? 152.751 162.732 163.238 1.00 48.47  ?  386 GLY B CA  1 
ATOM   8224  C  C   . GLY B 1 397 ? 153.807 162.882 164.310 1.00 48.47  ?  386 GLY B C   1 
ATOM   8225  O  O   . GLY B 1 397 ? 153.510 162.760 165.496 1.00 48.47  ?  386 GLY B O   1 
ATOM   8226  N  N   . VAL B 1 398 ? 155.051 163.150 163.916 1.00 49.37  ?  387 VAL B N   1 
ATOM   8227  C  CA  . VAL B 1 398 ? 156.086 163.381 164.913 1.00 49.37  ?  387 VAL B CA  1 
ATOM   8228  C  C   . VAL B 1 398 ? 155.777 164.630 165.715 1.00 49.37  ?  387 VAL B C   1 
ATOM   8229  O  O   . VAL B 1 398 ? 156.035 164.681 166.922 1.00 49.37  ?  387 VAL B O   1 
ATOM   8230  C  CB  . VAL B 1 398 ? 157.469 163.461 164.242 1.00 49.37  ?  387 VAL B CB  1 
ATOM   8231  C  CG1 . VAL B 1 398 ? 158.478 164.087 165.168 1.00 49.37  ?  387 VAL B CG1 1 
ATOM   8232  C  CG2 . VAL B 1 398 ? 157.928 162.085 163.834 1.00 49.37  ?  387 VAL B CG2 1 
ATOM   8233  N  N   . PHE B 1 399 ? 155.193 165.645 165.082 1.00 50.25  ?  388 PHE B N   1 
ATOM   8234  C  CA  . PHE B 1 399 ? 154.876 166.881 165.783 1.00 50.25  ?  388 PHE B CA  1 
ATOM   8235  C  C   . PHE B 1 399 ? 153.419 166.956 166.224 1.00 50.25  ?  388 PHE B C   1 
ATOM   8236  O  O   . PHE B 1 399 ? 152.889 168.050 166.427 1.00 50.25  ?  388 PHE B O   1 
ATOM   8237  C  CB  . PHE B 1 399 ? 155.252 168.076 164.921 1.00 50.25  ?  388 PHE B CB  1 
ATOM   8238  C  CG  . PHE B 1 399 ? 156.718 168.329 164.879 1.00 50.25  ?  388 PHE B CG  1 
ATOM   8239  C  CD1 . PHE B 1 399 ? 157.477 167.885 163.820 1.00 50.25  ?  388 PHE B CD1 1 
ATOM   8240  C  CD2 . PHE B 1 399 ? 157.344 168.985 165.915 1.00 50.25  ?  388 PHE B CD2 1 
ATOM   8241  C  CE1 . PHE B 1 399 ? 158.827 168.106 163.787 1.00 50.25  ?  388 PHE B CE1 1 
ATOM   8242  C  CE2 . PHE B 1 399 ? 158.692 169.208 165.885 1.00 50.25  ?  388 PHE B CE2 1 
ATOM   8243  C  CZ  . PHE B 1 399 ? 159.435 168.767 164.820 1.00 50.25  ?  388 PHE B CZ  1 
ATOM   8244  N  N   . ARG B 1 400 ? 152.776 165.800 166.392 1.00 54.43  ?  389 ARG B N   1 
ATOM   8245  C  CA  . ARG B 1 400 ? 151.479 165.619 167.049 1.00 54.43  ?  389 ARG B CA  1 
ATOM   8246  C  C   . ARG B 1 400 ? 150.301 166.110 166.213 1.00 54.43  ?  389 ARG B C   1 
ATOM   8247  O  O   . ARG B 1 400 ? 149.263 166.468 166.754 1.00 54.43  ?  389 ARG B O   1 
ATOM   8248  C  CB  . ARG B 1 400 ? 151.441 166.285 168.428 1.00 54.43  ?  389 ARG B CB  1 
ATOM   8249  C  CG  . ARG B 1 400 ? 152.678 166.074 169.261 1.00 54.43  ?  389 ARG B CG  1 
ATOM   8250  C  CD  . ARG B 1 400 ? 152.358 165.535 170.620 1.00 54.43  ?  389 ARG B CD  1 
ATOM   8251  N  NE  . ARG B 1 400 ? 153.547 165.547 171.458 1.00 54.43  ?  389 ARG B NE  1 
ATOM   8252  C  CZ  . ARG B 1 400 ? 153.597 166.069 172.673 1.00 54.43  ?  389 ARG B CZ  1 
ATOM   8253  N  NH1 . ARG B 1 400 ? 154.725 166.041 173.360 1.00 54.43  1  389 ARG B NH1 1 
ATOM   8254  N  NH2 . ARG B 1 400 ? 152.513 166.604 173.208 1.00 54.43  ?  389 ARG B NH2 1 
ATOM   8255  N  N   . GLY B 1 401 ? 150.436 166.104 164.895 1.00 48.67  ?  390 GLY B N   1 
ATOM   8256  C  CA  . GLY B 1 401 ? 149.297 166.287 164.022 1.00 48.67  ?  390 GLY B CA  1 
ATOM   8257  C  C   . GLY B 1 401 ? 148.735 164.942 163.616 1.00 48.67  ?  390 GLY B C   1 
ATOM   8258  O  O   . GLY B 1 401 ? 149.199 163.896 164.066 1.00 48.67  ?  390 GLY B O   1 
ATOM   8259  N  N   . PHE B 1 402 ? 147.723 164.958 162.759 1.00 45.36  ?  391 PHE B N   1 
ATOM   8260  C  CA  . PHE B 1 402 ? 147.169 163.710 162.259 1.00 45.36  ?  391 PHE B CA  1 
ATOM   8261  C  C   . PHE B 1 402 ? 147.204 163.702 160.740 1.00 45.36  ?  391 PHE B C   1 
ATOM   8262  O  O   . PHE B 1 402 ? 147.516 164.701 160.095 1.00 45.36  ?  391 PHE B O   1 
ATOM   8263  C  CB  . PHE B 1 402 ? 145.751 163.443 162.789 1.00 45.36  ?  391 PHE B CB  1 
ATOM   8264  C  CG  . PHE B 1 402 ? 144.794 164.573 162.600 1.00 45.36  ?  391 PHE B CG  1 
ATOM   8265  C  CD1 . PHE B 1 402 ? 144.020 164.658 161.465 1.00 45.36  ?  391 PHE B CD1 1 
ATOM   8266  C  CD2 . PHE B 1 402 ? 144.641 165.529 163.575 1.00 45.36  ?  391 PHE B CD2 1 
ATOM   8267  C  CE1 . PHE B 1 402 ? 143.137 165.684 161.299 1.00 45.36  ?  391 PHE B CE1 1 
ATOM   8268  C  CE2 . PHE B 1 402 ? 143.757 166.552 163.410 1.00 45.36  ?  391 PHE B CE2 1 
ATOM   8269  C  CZ  . PHE B 1 402 ? 143.007 166.632 162.271 1.00 45.36  ?  391 PHE B CZ  1 
ATOM   8270  N  N   . ALA B 1 403 ? 146.886 162.543 160.178 1.00 46.20  ?  392 ALA B N   1 
ATOM   8271  C  CA  . ALA B 1 403 ? 147.119 162.299 158.765 1.00 46.20  ?  392 ALA B CA  1 
ATOM   8272  C  C   . ALA B 1 403 ? 146.205 163.148 157.898 1.00 46.20  ?  392 ALA B C   1 
ATOM   8273  O  O   . ALA B 1 403 ? 145.082 163.476 158.279 1.00 46.20  ?  392 ALA B O   1 
ATOM   8274  C  CB  . ALA B 1 403 ? 146.916 160.821 158.448 1.00 46.20  ?  392 ALA B CB  1 
ATOM   8275  N  N   . GLY B 1 404 ? 146.701 163.503 156.722 1.00 47.33  ?  393 GLY B N   1 
ATOM   8276  C  CA  . GLY B 1 404 ? 145.906 164.230 155.757 1.00 47.33  ?  393 GLY B CA  1 
ATOM   8277  C  C   . GLY B 1 404 ? 146.652 164.367 154.456 1.00 47.33  ?  393 GLY B C   1 
ATOM   8278  O  O   . GLY B 1 404 ? 147.871 164.549 154.444 1.00 47.33  ?  393 GLY B O   1 
ATOM   8279  N  N   . SER B 1 405 ? 145.921 164.285 153.349 1.00 46.56  ?  394 SER B N   1 
ATOM   8280  C  CA  . SER B 1 405 ? 146.536 164.456 152.040 1.00 46.56  ?  394 SER B CA  1 
ATOM   8281  C  C   . SER B 1 405 ? 146.044 165.727 151.366 1.00 46.56  ?  394 SER B C   1 
ATOM   8282  O  O   . SER B 1 405 ? 146.848 166.613 151.089 1.00 46.56  ?  394 SER B O   1 
ATOM   8283  C  CB  . SER B 1 405 ? 146.263 163.234 151.170 1.00 46.56  ?  394 SER B CB  1 
ATOM   8284  O  OG  . SER B 1 405 ? 144.896 163.150 150.842 1.00 46.56  ?  394 SER B OG  1 
ATOM   8285  N  N   . THR B 1 406 ? 144.746 165.819 151.118 1.00 46.34  ?  395 THR B N   1 
ATOM   8286  C  CA  . THR B 1 406 ? 144.181 167.031 150.544 1.00 46.34  ?  395 THR B CA  1 
ATOM   8287  C  C   . THR B 1 406 ? 142.673 167.009 150.571 1.00 46.34  ?  395 THR B C   1 
ATOM   8288  O  O   . THR B 1 406 ? 142.062 165.952 150.460 1.00 46.34  ?  395 THR B O   1 
ATOM   8289  C  CB  . THR B 1 406 ? 144.636 167.252 149.085 1.00 46.34  ?  395 THR B CB  1 
ATOM   8290  O  OG1 . THR B 1 406 ? 144.186 168.533 148.634 1.00 46.34  ?  395 THR B OG1 1 
ATOM   8291  C  CG2 . THR B 1 406 ? 144.076 166.176 148.174 1.00 46.34  ?  395 THR B CG2 1 
ATOM   8292  N  N   . ALA B 1 407 ? 142.062 168.175 150.726 1.00 46.89  ?  396 ALA B N   1 
ATOM   8293  C  CA  . ALA B 1 407 ? 140.613 168.260 150.662 1.00 46.89  ?  396 ALA B CA  1 
ATOM   8294  C  C   . ALA B 1 407 ? 140.250 168.850 149.319 1.00 46.89  ?  396 ALA B C   1 
ATOM   8295  O  O   . ALA B 1 407 ? 140.825 169.849 148.911 1.00 46.89  ?  396 ALA B O   1 
ATOM   8296  C  CB  . ALA B 1 407 ? 140.066 169.111 151.787 1.00 46.89  ?  396 ALA B CB  1 
ATOM   8297  N  N   . LEU B 1 408 ? 139.306 168.235 148.621 1.00 48.52  ?  397 LEU B N   1 
ATOM   8298  C  CA  . LEU B 1 408 ? 138.874 168.740 147.327 1.00 48.52  ?  397 LEU B CA  1 
ATOM   8299  C  C   . LEU B 1 408 ? 138.336 170.148 147.457 1.00 48.52  ?  397 LEU B C   1 
ATOM   8300  O  O   . LEU B 1 408 ? 138.602 170.993 146.613 1.00 48.52  ?  397 LEU B O   1 
ATOM   8301  C  CB  . LEU B 1 408 ? 137.806 167.828 146.733 1.00 48.52  ?  397 LEU B CB  1 
ATOM   8302  C  CG  . LEU B 1 408 ? 137.192 168.285 145.411 1.00 48.52  ?  397 LEU B CG  1 
ATOM   8303  C  CD1 . LEU B 1 408 ? 138.250 168.339 144.321 1.00 48.52  ?  397 LEU B CD1 1 
ATOM   8304  C  CD2 . LEU B 1 408 ? 136.052 167.364 145.012 1.00 48.52  ?  397 LEU B CD2 1 
ATOM   8305  N  N   . SER B 1 409 ? 137.608 170.403 148.531 1.00 49.84  ?  398 SER B N   1 
ATOM   8306  C  CA  . SER B 1 409 ? 137.039 171.716 148.773 1.00 49.84  ?  398 SER B CA  1 
ATOM   8307  C  C   . SER B 1 409 ? 138.095 172.796 148.962 1.00 49.84  ?  398 SER B C   1 
ATOM   8308  O  O   . SER B 1 409 ? 137.917 173.905 148.491 1.00 49.84  ?  398 SER B O   1 
ATOM   8309  C  CB  . SER B 1 409 ? 136.082 171.684 149.959 1.00 49.84  ?  398 SER B CB  1 
ATOM   8310  O  OG  . SER B 1 409 ? 136.776 171.493 151.170 1.00 49.84  ?  398 SER B OG  1 
ATOM   8311  N  N   . ARG B 1 410 ? 139.183 172.479 149.658 1.00 46.10  ?  399 ARG B N   1 
ATOM   8312  C  CA  . ARG B 1 410 ? 140.264 173.431 149.871 1.00 46.10  ?  399 ARG B CA  1 
ATOM   8313  C  C   . ARG B 1 410 ? 141.153 173.576 148.644 1.00 46.10  ?  399 ARG B C   1 
ATOM   8314  O  O   . ARG B 1 410 ? 141.615 174.668 148.335 1.00 46.10  ?  399 ARG B O   1 
ATOM   8315  C  CB  . ARG B 1 410 ? 141.082 172.992 151.084 1.00 46.10  ?  399 ARG B CB  1 
ATOM   8316  C  CG  . ARG B 1 410 ? 141.899 174.081 151.750 1.00 46.10  ?  399 ARG B CG  1 
ATOM   8317  C  CD  . ARG B 1 410 ? 142.594 173.556 152.996 1.00 46.10  ?  399 ARG B CD  1 
ATOM   8318  N  NE  . ARG B 1 410 ? 143.339 172.326 152.736 1.00 46.10  ?  399 ARG B NE  1 
ATOM   8319  C  CZ  . ARG B 1 410 ? 142.993 171.124 153.186 1.00 46.10  ?  399 ARG B CZ  1 
ATOM   8320  N  NH1 . ARG B 1 410 ? 143.731 170.067 152.888 1.00 46.10  1  399 ARG B NH1 1 
ATOM   8321  N  NH2 . ARG B 1 410 ? 141.918 170.979 153.944 1.00 46.10  ?  399 ARG B NH2 1 
ATOM   8322  N  N   . SER B 1 411 ? 141.399 172.477 147.945 1.00 46.49  ?  400 SER B N   1 
ATOM   8323  C  CA  . SER B 1 411 ? 142.219 172.524 146.742 1.00 46.49  ?  400 SER B CA  1 
ATOM   8324  C  C   . SER B 1 411 ? 141.526 173.350 145.680 1.00 46.49  ?  400 SER B C   1 
ATOM   8325  O  O   . SER B 1 411 ? 142.172 174.113 144.966 1.00 46.49  ?  400 SER B O   1 
ATOM   8326  C  CB  . SER B 1 411 ? 142.509 171.114 146.241 1.00 46.49  ?  400 SER B CB  1 
ATOM   8327  O  OG  . SER B 1 411 ? 143.142 170.345 147.242 1.00 46.49  ?  400 SER B OG  1 
ATOM   8328  N  N   . ALA B 1 412 ? 140.212 173.214 145.584 1.00 46.65  ?  401 ALA B N   1 
ATOM   8329  C  CA  . ALA B 1 412 ? 139.441 173.997 144.632 1.00 46.65  ?  401 ALA B CA  1 
ATOM   8330  C  C   . ALA B 1 412 ? 139.537 175.469 144.959 1.00 46.65  ?  401 ALA B C   1 
ATOM   8331  O  O   . ALA B 1 412 ? 139.658 176.286 144.060 1.00 46.65  ?  401 ALA B O   1 
ATOM   8332  C  CB  . ALA B 1 412 ? 137.996 173.542 144.631 1.00 46.65  ?  401 ALA B CB  1 
ATOM   8333  N  N   . VAL B 1 413 ? 139.498 175.816 146.237 1.00 47.79  ?  402 VAL B N   1 
ATOM   8334  C  CA  . VAL B 1 413 ? 139.650 177.206 146.640 1.00 47.79  ?  402 VAL B CA  1 
ATOM   8335  C  C   . VAL B 1 413 ? 140.996 177.762 146.204 1.00 47.79  ?  402 VAL B C   1 
ATOM   8336  O  O   . VAL B 1 413 ? 141.066 178.842 145.638 1.00 47.79  ?  402 VAL B O   1 
ATOM   8337  C  CB  . VAL B 1 413 ? 139.498 177.366 148.166 1.00 47.79  ?  402 VAL B CB  1 
ATOM   8338  C  CG1 . VAL B 1 413 ? 139.882 178.769 148.607 1.00 47.79  ?  402 VAL B CG1 1 
ATOM   8339  C  CG2 . VAL B 1 413 ? 138.087 177.020 148.606 1.00 47.79  ?  402 VAL B CG2 1 
ATOM   8340  N  N   . GLN B 1 414 ? 142.062 177.015 146.439 1.00 48.37  ?  403 GLN B N   1 
ATOM   8341  C  CA  . GLN B 1 414 ? 143.395 177.473 146.071 1.00 48.37  ?  403 GLN B CA  1 
ATOM   8342  C  C   . GLN B 1 414 ? 143.489 177.698 144.575 1.00 48.37  ?  403 GLN B C   1 
ATOM   8343  O  O   . GLN B 1 414 ? 144.076 178.675 144.131 1.00 48.37  ?  403 GLN B O   1 
ATOM   8344  C  CB  . GLN B 1 414 ? 144.456 176.472 146.539 1.00 48.37  ?  403 GLN B CB  1 
ATOM   8345  C  CG  . GLN B 1 414 ? 145.882 176.826 146.158 1.00 48.37  ?  403 GLN B CG  1 
ATOM   8346  C  CD  . GLN B 1 414 ? 146.902 175.957 146.865 1.00 48.37  ?  403 GLN B CD  1 
ATOM   8347  O  OE1 . GLN B 1 414 ? 146.691 175.534 147.998 1.00 48.37  ?  403 GLN B OE1 1 
ATOM   8348  N  NE2 . GLN B 1 414 ? 148.021 175.696 146.202 1.00 48.37  ?  403 GLN B NE2 1 
ATOM   8349  N  N   . GLU B 1 415 ? 142.913 176.799 143.794 1.00 50.90  ?  404 GLU B N   1 
ATOM   8350  C  CA  . GLU B 1 415 ? 142.935 176.940 142.349 1.00 50.90  ?  404 GLU B CA  1 
ATOM   8351  C  C   . GLU B 1 415 ? 141.978 178.030 141.881 1.00 50.90  ?  404 GLU B C   1 
ATOM   8352  O  O   . GLU B 1 415 ? 142.321 178.833 141.023 1.00 50.90  ?  404 GLU B O   1 
ATOM   8353  C  CB  . GLU B 1 415 ? 142.623 175.591 141.686 1.00 50.90  ?  404 GLU B CB  1 
ATOM   8354  C  CG  . GLU B 1 415 ? 142.599 175.624 140.170 1.00 50.90  ?  404 GLU B CG  1 
ATOM   8355  C  CD  . GLU B 1 415 ? 141.253 176.050 139.629 1.00 50.90  ?  404 GLU B CD  1 
ATOM   8356  O  OE1 . GLU B 1 415 ? 140.227 175.679 140.233 1.00 50.90  ?  404 GLU B OE1 1 
ATOM   8357  O  OE2 . GLU B 1 415 ? 141.219 176.754 138.602 1.00 50.90  -1 404 GLU B OE2 1 
ATOM   8358  N  N   . SER B 1 416 ? 140.787 178.074 142.456 1.00 50.95  ?  405 SER B N   1 
ATOM   8359  C  CA  . SER B 1 416 ? 139.792 179.061 142.058 1.00 50.95  ?  405 SER B CA  1 
ATOM   8360  C  C   . SER B 1 416 ? 140.180 180.474 142.446 1.00 50.95  ?  405 SER B C   1 
ATOM   8361  O  O   . SER B 1 416 ? 139.765 181.430 141.798 1.00 50.95  ?  405 SER B O   1 
ATOM   8362  C  CB  . SER B 1 416 ? 138.445 178.720 142.676 1.00 50.95  ?  405 SER B CB  1 
ATOM   8363  O  OG  . SER B 1 416 ? 137.488 179.721 142.391 1.00 50.95  ?  405 SER B OG  1 
ATOM   8364  N  N   . THR B 1 417 ? 140.973 180.616 143.498 1.00 51.34  ?  406 THR B N   1 
ATOM   8365  C  CA  . THR B 1 417 ? 141.395 181.936 143.950 1.00 51.34  ?  406 THR B CA  1 
ATOM   8366  C  C   . THR B 1 417 ? 142.617 182.399 143.192 1.00 51.34  ?  406 THR B C   1 
ATOM   8367  O  O   . THR B 1 417 ? 143.170 183.453 143.488 1.00 51.34  ?  406 THR B O   1 
ATOM   8368  C  CB  . THR B 1 417 ? 141.679 181.947 145.457 1.00 51.34  ?  406 THR B CB  1 
ATOM   8369  O  OG1 . THR B 1 417 ? 142.528 180.843 145.789 1.00 51.34  ?  406 THR B OG1 1 
ATOM   8370  C  CG2 . THR B 1 417 ? 140.383 181.829 146.235 1.00 51.34  ?  406 THR B CG2 1 
ATOM   8371  N  N   . GLY B 1 418 ? 143.054 181.613 142.220 1.00 51.74  ?  407 GLY B N   1 
ATOM   8372  C  CA  . GLY B 1 418 ? 144.167 182.031 141.392 1.00 51.74  ?  407 GLY B CA  1 
ATOM   8373  C  C   . GLY B 1 418 ? 145.494 181.390 141.678 1.00 51.74  ?  407 GLY B C   1 
ATOM   8374  O  O   . GLY B 1 418 ? 146.529 181.907 141.280 1.00 51.74  ?  407 GLY B O   1 
ATOM   8375  N  N   . GLY B 1 419 ? 145.476 180.261 142.362 1.00 52.76  ?  408 GLY B N   1 
ATOM   8376  C  CA  . GLY B 1 419 ? 146.709 179.591 142.712 1.00 52.76  ?  408 GLY B CA  1 
ATOM   8377  C  C   . GLY B 1 419 ? 147.495 179.108 141.518 1.00 52.76  ?  408 GLY B C   1 
ATOM   8378  O  O   . GLY B 1 419 ? 146.956 178.431 140.645 1.00 52.76  ?  408 GLY B O   1 
ATOM   8379  N  N   . LYS B 1 420 ? 148.773 179.449 141.471 1.00 54.60  ?  409 LYS B N   1 
ATOM   8380  C  CA  . LYS B 1 420 ? 149.644 179.062 140.373 1.00 54.60  ?  409 LYS B CA  1 
ATOM   8381  C  C   . LYS B 1 420 ? 150.631 177.974 140.746 1.00 54.60  ?  409 LYS B C   1 
ATOM   8382  O  O   . LYS B 1 420 ? 150.709 176.961 140.058 1.00 54.60  ?  409 LYS B O   1 
ATOM   8383  C  CB  . LYS B 1 420 ? 150.410 180.283 139.864 1.00 54.60  ?  409 LYS B CB  1 
ATOM   8384  C  CG  . LYS B 1 420 ? 149.520 181.358 139.299 1.00 54.60  ?  409 LYS B CG  1 
ATOM   8385  C  CD  . LYS B 1 420 ? 148.824 180.872 138.054 1.00 54.60  ?  409 LYS B CD  1 
ATOM   8386  C  CE  . LYS B 1 420 ? 148.040 181.978 137.393 1.00 54.60  ?  409 LYS B CE  1 
ATOM   8387  N  NZ  . LYS B 1 420 ? 146.748 182.223 138.065 1.00 54.60  1  409 LYS B NZ  1 
ATOM   8388  N  N   . THR B 1 421 ? 151.386 178.157 141.824 1.00 54.33  ?  410 THR B N   1 
ATOM   8389  C  CA  . THR B 1 421 ? 152.336 177.152 142.275 1.00 54.33  ?  410 THR B CA  1 
ATOM   8390  C  C   . THR B 1 421 ? 152.020 176.732 143.698 1.00 54.33  ?  410 THR B C   1 
ATOM   8391  O  O   . THR B 1 421 ? 150.995 177.128 144.256 1.00 54.33  ?  410 THR B O   1 
ATOM   8392  C  CB  . THR B 1 421 ? 153.766 177.676 142.211 1.00 54.33  ?  410 THR B CB  1 
ATOM   8393  O  OG1 . THR B 1 421 ? 153.871 178.855 143.008 1.00 54.33  ?  410 THR B OG1 1 
ATOM   8394  C  CG2 . THR B 1 421 ? 154.146 178.009 140.801 1.00 54.33  ?  410 THR B CG2 1 
ATOM   8395  N  N   . GLN B 1 422 ? 152.897 175.932 144.289 1.00 50.28  ?  411 GLN B N   1 
ATOM   8396  C  CA  . GLN B 1 422 ? 152.786 175.559 145.687 1.00 50.28  ?  411 GLN B CA  1 
ATOM   8397  C  C   . GLN B 1 422 ? 153.339 176.627 146.618 1.00 50.28  ?  411 GLN B C   1 
ATOM   8398  O  O   . GLN B 1 422 ? 153.588 176.340 147.788 1.00 50.28  ?  411 GLN B O   1 
ATOM   8399  C  CB  . GLN B 1 422 ? 153.486 174.221 145.924 1.00 50.28  ?  411 GLN B CB  1 
ATOM   8400  C  CG  . GLN B 1 422 ? 152.720 173.288 146.824 1.00 50.28  ?  411 GLN B CG  1 
ATOM   8401  C  CD  . GLN B 1 422 ? 151.341 172.962 146.307 1.00 50.28  ?  411 GLN B CD  1 
ATOM   8402  O  OE1 . GLN B 1 422 ? 151.185 172.411 145.234 1.00 50.28  ?  411 GLN B OE1 1 
ATOM   8403  N  NE2 . GLN B 1 422 ? 150.330 173.323 147.068 1.00 50.28  ?  411 GLN B NE2 1 
ATOM   8404  N  N   . ILE B 1 423 ? 153.552 177.843 146.117 1.00 51.83  ?  412 ILE B N   1 
ATOM   8405  C  CA  . ILE B 1 423 ? 153.805 178.991 146.981 1.00 51.83  ?  412 ILE B CA  1 
ATOM   8406  C  C   . ILE B 1 423 ? 152.517 179.425 147.666 1.00 51.83  ?  412 ILE B C   1 
ATOM   8407  O  O   . ILE B 1 423 ? 152.543 179.954 148.784 1.00 51.83  ?  412 ILE B O   1 
ATOM   8408  C  CB  . ILE B 1 423 ? 154.437 180.133 146.162 1.00 51.83  ?  412 ILE B CB  1 
ATOM   8409  C  CG1 . ILE B 1 423 ? 155.851 179.758 145.723 1.00 51.83  ?  412 ILE B CG1 1 
ATOM   8410  C  CG2 . ILE B 1 423 ? 154.471 181.423 146.941 1.00 51.83  ?  412 ILE B CG2 1 
ATOM   8411  C  CD1 . ILE B 1 423 ? 156.817 179.614 146.850 1.00 51.83  ?  412 ILE B CD1 1 
ATOM   8412  N  N   . ALA B 1 424 ? 151.373 179.190 147.029 1.00 49.58  ?  413 ALA B N   1 
ATOM   8413  C  CA  . ALA B 1 424 ? 150.099 179.413 147.698 1.00 49.58  ?  413 ALA B CA  1 
ATOM   8414  C  C   . ALA B 1 424 ? 149.944 178.491 148.900 1.00 49.58  ?  413 ALA B C   1 
ATOM   8415  O  O   . ALA B 1 424 ? 149.402 178.892 149.935 1.00 49.58  ?  413 ALA B O   1 
ATOM   8416  C  CB  . ALA B 1 424 ? 148.953 179.219 146.712 1.00 49.58  ?  413 ALA B CB  1 
ATOM   8417  N  N   . GLY B 1 425 ? 150.435 177.258 148.793 1.00 48.86  ?  414 GLY B N   1 
ATOM   8418  C  CA  . GLY B 1 425 ? 150.433 176.373 149.943 1.00 48.86  ?  414 GLY B CA  1 
ATOM   8419  C  C   . GLY B 1 425 ? 151.337 176.859 151.058 1.00 48.86  ?  414 GLY B C   1 
ATOM   8420  O  O   . GLY B 1 425 ? 151.004 176.731 152.237 1.00 48.86  ?  414 GLY B O   1 
ATOM   8421  N  N   . LEU B 1 426 ? 152.485 177.433 150.704 1.00 49.27  ?  415 LEU B N   1 
ATOM   8422  C  CA  . LEU B 1 426 ? 153.374 177.990 151.714 1.00 49.27  ?  415 LEU B CA  1 
ATOM   8423  C  C   . LEU B 1 426 ? 152.725 179.163 152.434 1.00 49.27  ?  415 LEU B C   1 
ATOM   8424  O  O   . LEU B 1 426 ? 152.819 179.277 153.660 1.00 49.27  ?  415 LEU B O   1 
ATOM   8425  C  CB  . LEU B 1 426 ? 154.689 178.418 151.073 1.00 49.27  ?  415 LEU B CB  1 
ATOM   8426  C  CG  . LEU B 1 426 ? 155.620 179.275 151.926 1.00 49.27  ?  415 LEU B CG  1 
ATOM   8427  C  CD1 . LEU B 1 426 ? 156.092 178.500 153.130 1.00 49.27  ?  415 LEU B CD1 1 
ATOM   8428  C  CD2 . LEU B 1 426 ? 156.794 179.746 151.111 1.00 49.27  ?  415 LEU B CD2 1 
ATOM   8429  N  N   . ILE B 1 427 ? 152.053 180.041 151.695 1.00 49.17  ?  416 ILE B N   1 
ATOM   8430  C  CA  . ILE B 1 427 ? 151.413 181.182 152.337 1.00 49.17  ?  416 ILE B CA  1 
ATOM   8431  C  C   . ILE B 1 427 ? 150.231 180.734 153.188 1.00 49.17  ?  416 ILE B C   1 
ATOM   8432  O  O   . ILE B 1 427 ? 149.979 181.295 154.261 1.00 49.17  ?  416 ILE B O   1 
ATOM   8433  C  CB  . ILE B 1 427 ? 151.026 182.215 151.266 1.00 49.17  ?  416 ILE B CB  1 
ATOM   8434  C  CG1 . ILE B 1 427 ? 152.296 182.862 150.724 1.00 49.17  ?  416 ILE B CG1 1 
ATOM   8435  C  CG2 . ILE B 1 427 ? 150.095 183.265 151.821 1.00 49.17  ?  416 ILE B CG2 1 
ATOM   8436  C  CD1 . ILE B 1 427 ? 152.080 183.754 149.573 1.00 49.17  ?  416 ILE B CD1 1 
ATOM   8437  N  N   . GLY B 1 428 ? 149.510 179.702 152.755 1.00 48.25  ?  417 GLY B N   1 
ATOM   8438  C  CA  . GLY B 1 428 ? 148.459 179.155 153.594 1.00 48.25  ?  417 GLY B CA  1 
ATOM   8439  C  C   . GLY B 1 428 ? 148.988 178.566 154.886 1.00 48.25  ?  417 GLY B C   1 
ATOM   8440  O  O   . GLY B 1 428 ? 148.404 178.760 155.956 1.00 48.25  ?  417 GLY B O   1 
ATOM   8441  N  N   . ALA B 1 429 ? 150.101 177.838 154.806 1.00 47.88  ?  418 ALA B N   1 
ATOM   8442  C  CA  . ALA B 1 429 ? 150.726 177.318 156.014 1.00 47.88  ?  418 ALA B CA  1 
ATOM   8443  C  C   . ALA B 1 429 ? 151.243 178.437 156.906 1.00 47.88  ?  418 ALA B C   1 
ATOM   8444  O  O   . ALA B 1 429 ? 151.262 178.288 158.127 1.00 47.88  ?  418 ALA B O   1 
ATOM   8445  C  CB  . ALA B 1 429 ? 151.852 176.355 155.648 1.00 47.88  ?  418 ALA B CB  1 
ATOM   8446  N  N   . ILE B 1 430 ? 151.647 179.565 156.330 1.00 49.05  ?  419 ILE B N   1 
ATOM   8447  C  CA  . ILE B 1 430 ? 152.054 180.698 157.158 1.00 49.05  ?  419 ILE B CA  1 
ATOM   8448  C  C   . ILE B 1 430 ? 150.854 181.300 157.877 1.00 49.05  ?  419 ILE B C   1 
ATOM   8449  O  O   . ILE B 1 430 ? 150.964 181.751 159.020 1.00 49.05  ?  419 ILE B O   1 
ATOM   8450  C  CB  . ILE B 1 430 ? 152.792 181.748 156.310 1.00 49.05  ?  419 ILE B CB  1 
ATOM   8451  C  CG1 . ILE B 1 430 ? 154.156 181.223 155.887 1.00 49.05  ?  419 ILE B CG1 1 
ATOM   8452  C  CG2 . ILE B 1 430 ? 152.970 183.033 157.078 1.00 49.05  ?  419 ILE B CG2 1 
ATOM   8453  C  CD1 . ILE B 1 430 ? 154.846 182.108 154.898 1.00 49.05  ?  419 ILE B CD1 1 
ATOM   8454  N  N   . ILE B 1 431 ? 149.693 181.327 157.228 1.00 49.77  ?  420 ILE B N   1 
ATOM   8455  C  CA  . ILE B 1 431 ? 148.485 181.771 157.922 1.00 49.77  ?  420 ILE B CA  1 
ATOM   8456  C  C   . ILE B 1 431 ? 148.158 180.833 159.080 1.00 49.77  ?  420 ILE B C   1 
ATOM   8457  O  O   . ILE B 1 431 ? 147.816 181.273 160.188 1.00 49.77  ?  420 ILE B O   1 
ATOM   8458  C  CB  . ILE B 1 431 ? 147.310 181.878 156.935 1.00 49.77  ?  420 ILE B CB  1 
ATOM   8459  C  CG1 . ILE B 1 431 ? 147.621 182.902 155.848 1.00 49.77  ?  420 ILE B CG1 1 
ATOM   8460  C  CG2 . ILE B 1 431 ? 146.027 182.207 157.666 1.00 49.77  ?  420 ILE B CG2 1 
ATOM   8461  C  CD1 . ILE B 1 431 ? 147.185 184.280 156.174 1.00 49.77  ?  420 ILE B CD1 1 
ATOM   8462  N  N   . VAL B 1 432 ? 148.257 179.527 158.840 1.00 48.67  ?  421 VAL B N   1 
ATOM   8463  C  CA  . VAL B 1 432 ? 148.031 178.555 159.904 1.00 48.67  ?  421 VAL B CA  1 
ATOM   8464  C  C   . VAL B 1 432 ? 149.024 178.766 161.040 1.00 48.67  ?  421 VAL B C   1 
ATOM   8465  O  O   . VAL B 1 432 ? 148.678 178.650 162.218 1.00 48.67  ?  421 VAL B O   1 
ATOM   8466  C  CB  . VAL B 1 432 ? 148.109 177.129 159.337 1.00 48.67  ?  421 VAL B CB  1 
ATOM   8467  C  CG1 . VAL B 1 432 ? 148.004 176.116 160.443 1.00 48.67  ?  421 VAL B CG1 1 
ATOM   8468  C  CG2 . VAL B 1 432 ? 147.022 176.914 158.314 1.00 48.67  ?  421 VAL B CG2 1 
ATOM   8469  N  N   . LEU B 1 433 ? 150.269 179.086 160.701 1.00 49.33  ?  422 LEU B N   1 
ATOM   8470  C  CA  . LEU B 1 433 ? 151.289 179.358 161.706 1.00 49.33  ?  422 LEU B CA  1 
ATOM   8471  C  C   . LEU B 1 433 ? 150.936 180.582 162.534 1.00 49.33  ?  422 LEU B C   1 
ATOM   8472  O  O   . LEU B 1 433 ? 151.111 180.588 163.755 1.00 49.33  ?  422 LEU B O   1 
ATOM   8473  C  CB  . LEU B 1 433 ? 152.637 179.547 161.017 1.00 49.33  ?  422 LEU B CB  1 
ATOM   8474  C  CG  . LEU B 1 433 ? 153.822 180.022 161.841 1.00 49.33  ?  422 LEU B CG  1 
ATOM   8475  C  CD1 . LEU B 1 433 ? 154.463 178.846 162.514 1.00 49.33  ?  422 LEU B CD1 1 
ATOM   8476  C  CD2 . LEU B 1 433 ? 154.817 180.715 160.960 1.00 49.33  ?  422 LEU B CD2 1 
ATOM   8477  N  N   . ILE B 1 434 ? 150.462 181.639 161.880 1.00 51.88  ?  423 ILE B N   1 
ATOM   8478  C  CA  . ILE B 1 434 ? 150.078 182.856 162.589 1.00 51.88  ?  423 ILE B CA  1 
ATOM   8479  C  C   . ILE B 1 434 ? 148.959 182.560 163.575 1.00 51.88  ?  423 ILE B C   1 
ATOM   8480  O  O   . ILE B 1 434 ? 148.939 183.084 164.695 1.00 51.88  ?  423 ILE B O   1 
ATOM   8481  C  CB  . ILE B 1 434 ? 149.677 183.952 161.586 1.00 51.88  ?  423 ILE B CB  1 
ATOM   8482  C  CG1 . ILE B 1 434 ? 150.914 184.495 160.881 1.00 51.88  ?  423 ILE B CG1 1 
ATOM   8483  C  CG2 . ILE B 1 434 ? 148.931 185.078 162.272 1.00 51.88  ?  423 ILE B CG2 1 
ATOM   8484  C  CD1 . ILE B 1 434 ? 150.605 185.439 159.763 1.00 51.88  ?  423 ILE B CD1 1 
ATOM   8485  N  N   . VAL B 1 435 ? 148.010 181.712 163.175 1.00 52.25  ?  424 VAL B N   1 
ATOM   8486  C  CA  . VAL B 1 435 ? 146.944 181.335 164.102 1.00 52.25  ?  424 VAL B CA  1 
ATOM   8487  C  C   . VAL B 1 435 ? 147.493 180.520 165.266 1.00 52.25  ?  424 VAL B C   1 
ATOM   8488  O  O   . VAL B 1 435 ? 147.151 180.766 166.424 1.00 52.25  ?  424 VAL B O   1 
ATOM   8489  C  CB  . VAL B 1 435 ? 145.827 180.576 163.367 1.00 52.25  ?  424 VAL B CB  1 
ATOM   8490  C  CG1 . VAL B 1 435 ? 144.803 180.076 164.354 1.00 52.25  ?  424 VAL B CG1 1 
ATOM   8491  C  CG2 . VAL B 1 435 ? 145.163 181.480 162.364 1.00 52.25  ?  424 VAL B CG2 1 
ATOM   8492  N  N   . VAL B 1 436 ? 148.347 179.541 164.982 1.00 51.34  ?  425 VAL B N   1 
ATOM   8493  C  CA  . VAL B 1 436 ? 148.894 178.688 166.034 1.00 51.34  ?  425 VAL B CA  1 
ATOM   8494  C  C   . VAL B 1 436 ? 149.690 179.505 167.043 1.00 51.34  ?  425 VAL B C   1 
ATOM   8495  O  O   . VAL B 1 436 ? 149.633 179.248 168.249 1.00 51.34  ?  425 VAL B O   1 
ATOM   8496  C  CB  . VAL B 1 436 ? 149.753 177.571 165.413 1.00 51.34  ?  425 VAL B CB  1 
ATOM   8497  C  CG1 . VAL B 1 436 ? 150.599 176.899 166.459 1.00 51.34  ?  425 VAL B CG1 1 
ATOM   8498  C  CG2 . VAL B 1 436 ? 148.881 176.568 164.722 1.00 51.34  ?  425 VAL B CG2 1 
ATOM   8499  N  N   . LEU B 1 437 ? 150.433 180.507 166.578 1.00 53.28  ?  426 LEU B N   1 
ATOM   8500  C  CA  . LEU B 1 437 ? 151.341 181.237 167.451 1.00 53.28  ?  426 LEU B CA  1 
ATOM   8501  C  C   . LEU B 1 437 ? 150.724 182.478 168.078 1.00 53.28  ?  426 LEU B C   1 
ATOM   8502  O  O   . LEU B 1 437 ? 151.009 182.771 169.241 1.00 53.28  ?  426 LEU B O   1 
ATOM   8503  C  CB  . LEU B 1 437 ? 152.598 181.649 166.685 1.00 53.28  ?  426 LEU B CB  1 
ATOM   8504  C  CG  . LEU B 1 437 ? 153.575 180.550 166.280 1.00 53.28  ?  426 LEU B CG  1 
ATOM   8505  C  CD1 . LEU B 1 437 ? 154.804 181.161 165.668 1.00 53.28  ?  426 LEU B CD1 1 
ATOM   8506  C  CD2 . LEU B 1 437 ? 153.946 179.692 167.461 1.00 53.28  ?  426 LEU B CD2 1 
ATOM   8507  N  N   . ALA B 1 438 ? 149.905 183.224 167.352 1.00 56.20  ?  427 ALA B N   1 
ATOM   8508  C  CA  . ALA B 1 438 ? 149.556 184.569 167.791 1.00 56.20  ?  427 ALA B CA  1 
ATOM   8509  C  C   . ALA B 1 438 ? 148.075 184.793 168.038 1.00 56.20  ?  427 ALA B C   1 
ATOM   8510  O  O   . ALA B 1 438 ? 147.713 185.350 169.073 1.00 56.20  ?  427 ALA B O   1 
ATOM   8511  C  CB  . ALA B 1 438 ? 150.049 185.594 166.765 1.00 56.20  ?  427 ALA B CB  1 
ATOM   8512  N  N   . ILE B 1 439 ? 147.204 184.389 167.120 1.00 56.44  ?  428 ILE B N   1 
ATOM   8513  C  CA  . ILE B 1 439 ? 145.815 184.827 167.161 1.00 56.44  ?  428 ILE B CA  1 
ATOM   8514  C  C   . ILE B 1 439 ? 144.866 183.648 167.292 1.00 56.44  ?  428 ILE B C   1 
ATOM   8515  O  O   . ILE B 1 439 ? 143.724 183.708 166.831 1.00 56.44  ?  428 ILE B O   1 
ATOM   8516  C  CB  . ILE B 1 439 ? 145.465 185.661 165.917 1.00 56.44  ?  428 ILE B CB  1 
ATOM   8517  C  CG1 . ILE B 1 439 ? 145.666 184.840 164.649 1.00 56.44  ?  428 ILE B CG1 1 
ATOM   8518  C  CG2 . ILE B 1 439 ? 146.309 186.908 165.859 1.00 56.44  ?  428 ILE B CG2 1 
ATOM   8519  C  CD1 . ILE B 1 439 ? 144.860 185.329 163.487 1.00 56.44  ?  428 ILE B CD1 1 
ATOM   8520  N  N   . GLY B 1 440 ? 145.317 182.570 167.925 1.00 57.60  ?  429 GLY B N   1 
ATOM   8521  C  CA  . GLY B 1 440 ? 144.409 181.469 168.183 1.00 57.60  ?  429 GLY B CA  1 
ATOM   8522  C  C   . GLY B 1 440 ? 143.311 181.794 169.170 1.00 57.60  ?  429 GLY B C   1 
ATOM   8523  O  O   . GLY B 1 440 ? 142.218 181.229 169.068 1.00 57.60  ?  429 GLY B O   1 
ATOM   8524  N  N   . PHE B 1 441 ? 143.571 182.704 170.109 1.00 59.04  ?  430 PHE B N   1 
ATOM   8525  C  CA  . PHE B 1 441 ? 142.570 183.104 171.089 1.00 59.04  ?  430 PHE B CA  1 
ATOM   8526  C  C   . PHE B 1 441 ? 141.310 183.661 170.447 1.00 59.04  ?  430 PHE B C   1 
ATOM   8527  O  O   . PHE B 1 441 ? 140.257 183.662 171.086 1.00 59.04  ?  430 PHE B O   1 
ATOM   8528  C  CB  . PHE B 1 441 ? 143.155 184.146 172.036 1.00 59.04  ?  430 PHE B CB  1 
ATOM   8529  C  CG  . PHE B 1 441 ? 143.405 185.472 171.390 1.00 59.04  ?  430 PHE B CG  1 
ATOM   8530  C  CD1 . PHE B 1 441 ? 144.570 185.704 170.690 1.00 59.04  ?  430 PHE B CD1 1 
ATOM   8531  C  CD2 . PHE B 1 441 ? 142.475 186.486 171.478 1.00 59.04  ?  430 PHE B CD2 1 
ATOM   8532  C  CE1 . PHE B 1 441 ? 144.799 186.915 170.092 1.00 59.04  ?  430 PHE B CE1 1 
ATOM   8533  C  CE2 . PHE B 1 441 ? 142.703 187.698 170.877 1.00 59.04  ?  430 PHE B CE2 1 
ATOM   8534  C  CZ  . PHE B 1 441 ? 143.867 187.911 170.186 1.00 59.04  ?  430 PHE B CZ  1 
ATOM   8535  N  N   . LEU B 1 442 ? 141.399 184.155 169.214 1.00 59.99  ?  431 LEU B N   1 
ATOM   8536  C  CA  . LEU B 1 442 ? 140.219 184.670 168.537 1.00 59.99  ?  431 LEU B CA  1 
ATOM   8537  C  C   . LEU B 1 442 ? 139.202 183.575 168.271 1.00 59.99  ?  431 LEU B C   1 
ATOM   8538  O  O   . LEU B 1 442 ? 138.007 183.859 168.153 1.00 59.99  ?  431 LEU B O   1 
ATOM   8539  C  CB  . LEU B 1 442 ? 140.614 185.334 167.224 1.00 59.99  ?  431 LEU B CB  1 
ATOM   8540  C  CG  . LEU B 1 442 ? 141.258 186.712 167.258 1.00 59.99  ?  431 LEU B CG  1 
ATOM   8541  C  CD1 . LEU B 1 442 ? 141.737 187.062 165.876 1.00 59.99  ?  431 LEU B CD1 1 
ATOM   8542  C  CD2 . LEU B 1 442 ? 140.274 187.743 167.749 1.00 59.99  ?  431 LEU B CD2 1 
ATOM   8543  N  N   . LEU B 1 443 ? 139.646 182.328 168.166 1.00 59.85  ?  432 LEU B N   1 
ATOM   8544  C  CA  . LEU B 1 443 ? 138.757 181.226 167.843 1.00 59.85  ?  432 LEU B CA  1 
ATOM   8545  C  C   . LEU B 1 443 ? 138.222 180.523 169.075 1.00 59.85  ?  432 LEU B C   1 
ATOM   8546  O  O   . LEU B 1 443 ? 137.540 179.506 168.943 1.00 59.85  ?  432 LEU B O   1 
ATOM   8547  C  CB  . LEU B 1 443 ? 139.475 180.221 166.947 1.00 59.85  ?  432 LEU B CB  1 
ATOM   8548  C  CG  . LEU B 1 443 ? 139.919 180.750 165.589 1.00 59.85  ?  432 LEU B CG  1 
ATOM   8549  C  CD1 . LEU B 1 443 ? 141.076 179.935 165.082 1.00 59.85  ?  432 LEU B CD1 1 
ATOM   8550  C  CD2 . LEU B 1 443 ? 138.766 180.715 164.611 1.00 59.85  ?  432 LEU B CD2 1 
ATOM   8551  N  N   . ALA B 1 444 ? 138.505 181.039 170.257 1.00 61.29  ?  433 ALA B N   1 
ATOM   8552  C  CA  . ALA B 1 444 ? 138.068 180.415 171.496 1.00 61.29  ?  433 ALA B CA  1 
ATOM   8553  C  C   . ALA B 1 444 ? 136.549 180.385 171.638 1.00 61.29  ?  433 ALA B C   1 
ATOM   8554  O  O   . ALA B 1 444 ? 136.005 179.342 172.017 1.00 61.29  ?  433 ALA B O   1 
ATOM   8555  C  CB  . ALA B 1 444 ? 138.696 181.121 172.697 1.00 61.29  ?  433 ALA B CB  1 
ATOM   8556  N  N   . PRO B 1 445 ? 135.817 181.468 171.367 1.00 61.10  ?  434 PRO B N   1 
ATOM   8557  C  CA  . PRO B 1 445 ? 134.366 181.433 171.558 1.00 61.10  ?  434 PRO B CA  1 
ATOM   8558  C  C   . PRO B 1 445 ? 133.583 180.790 170.426 1.00 61.10  ?  434 PRO B C   1 
ATOM   8559  O  O   . PRO B 1 445 ? 132.354 180.871 170.435 1.00 61.10  ?  434 PRO B O   1 
ATOM   8560  C  CB  . PRO B 1 445 ? 134.015 182.919 171.679 1.00 61.10  ?  434 PRO B CB  1 
ATOM   8561  C  CG  . PRO B 1 445 ? 134.992 183.573 170.837 1.00 61.10  ?  434 PRO B CG  1 
ATOM   8562  C  CD  . PRO B 1 445 ? 136.262 182.832 171.026 1.00 61.10  ?  434 PRO B CD  1 
ATOM   8563  N  N   . LEU B 1 446 ? 134.231 180.157 169.459 1.00 58.77  ?  435 LEU B N   1 
ATOM   8564  C  CA  . LEU B 1 446 ? 133.511 179.554 168.351 1.00 58.77  ?  435 LEU B CA  1 
ATOM   8565  C  C   . LEU B 1 446 ? 132.928 178.209 168.755 1.00 58.77  ?  435 LEU B C   1 
ATOM   8566  O  O   . LEU B 1 446 ? 133.630 177.345 169.279 1.00 58.77  ?  435 LEU B O   1 
ATOM   8567  C  CB  . LEU B 1 446 ? 134.435 179.385 167.151 1.00 58.77  ?  435 LEU B CB  1 
ATOM   8568  C  CG  . LEU B 1 446 ? 133.832 178.694 165.935 1.00 58.77  ?  435 LEU B CG  1 
ATOM   8569  C  CD1 . LEU B 1 446 ? 132.702 179.519 165.370 1.00 58.77  ?  435 LEU B CD1 1 
ATOM   8570  C  CD2 . LEU B 1 446 ? 134.897 178.465 164.899 1.00 58.77  ?  435 LEU B CD2 1 
ATOM   8571  N  N   . GLN B 1 447 ? 131.636 178.035 168.499 1.00 58.88  ?  436 GLN B N   1 
ATOM   8572  C  CA  . GLN B 1 447 ? 130.931 176.814 168.844 1.00 58.88  ?  436 GLN B CA  1 
ATOM   8573  C  C   . GLN B 1 447 ? 131.319 175.671 167.916 1.00 58.88  ?  436 GLN B C   1 
ATOM   8574  O  O   . GLN B 1 447 ? 131.552 175.855 166.723 1.00 58.88  ?  436 GLN B O   1 
ATOM   8575  C  CB  . GLN B 1 447 ? 129.424 177.021 168.771 1.00 58.88  ?  436 GLN B CB  1 
ATOM   8576  C  CG  . GLN B 1 447 ? 128.898 178.143 169.613 1.00 58.88  ?  436 GLN B CG  1 
ATOM   8577  C  CD  . GLN B 1 447 ? 127.472 178.483 169.265 1.00 58.88  ?  436 GLN B CD  1 
ATOM   8578  O  OE1 . GLN B 1 447 ? 126.575 177.657 169.403 1.00 58.88  ?  436 GLN B OE1 1 
ATOM   8579  N  NE2 . GLN B 1 447 ? 127.254 179.701 168.798 1.00 58.88  ?  436 GLN B NE2 1 
ATOM   8580  N  N   . LYS B 1 448 ? 131.363 174.470 168.479 1.00 54.54  ?  437 LYS B N   1 
ATOM   8581  C  CA  . LYS B 1 448 ? 131.639 173.286 167.683 1.00 54.54  ?  437 LYS B CA  1 
ATOM   8582  C  C   . LYS B 1 448 ? 130.497 172.939 166.745 1.00 54.54  ?  437 LYS B C   1 
ATOM   8583  O  O   . LYS B 1 448 ? 130.728 172.302 165.711 1.00 54.54  ?  437 LYS B O   1 
ATOM   8584  C  CB  . LYS B 1 448 ? 131.931 172.103 168.596 1.00 54.54  ?  437 LYS B CB  1 
ATOM   8585  C  CG  . LYS B 1 448 ? 133.000 172.375 169.612 1.00 54.54  ?  437 LYS B CG  1 
ATOM   8586  C  CD  . LYS B 1 448 ? 133.382 171.114 170.330 1.00 54.54  ?  437 LYS B CD  1 
ATOM   8587  C  CE  . LYS B 1 448 ? 134.529 171.351 171.266 1.00 54.54  ?  437 LYS B CE  1 
ATOM   8588  N  NZ  . LYS B 1 448 ? 135.004 170.079 171.857 1.00 54.54  1  437 LYS B NZ  1 
ATOM   8589  N  N   . SER B 1 449 ? 129.275 173.349 167.081 1.00 55.50  ?  438 SER B N   1 
ATOM   8590  C  CA  . SER B 1 449 ? 128.146 173.098 166.200 1.00 55.50  ?  438 SER B CA  1 
ATOM   8591  C  C   . SER B 1 449 ? 128.289 173.864 164.896 1.00 55.50  ?  438 SER B C   1 
ATOM   8592  O  O   . SER B 1 449 ? 127.830 173.402 163.852 1.00 55.50  ?  438 SER B O   1 
ATOM   8593  C  CB  . SER B 1 449 ? 126.845 173.467 166.899 1.00 55.50  ?  438 SER B CB  1 
ATOM   8594  O  OG  . SER B 1 449 ? 126.873 174.809 167.324 1.00 55.50  ?  438 SER B OG  1 
ATOM   8595  N  N   . VAL B 1 450 ? 128.953 175.018 164.930 1.00 56.17  ?  439 VAL B N   1 
ATOM   8596  C  CA  . VAL B 1 450 ? 129.149 175.802 163.716 1.00 56.17  ?  439 VAL B CA  1 
ATOM   8597  C  C   . VAL B 1 450 ? 130.139 175.115 162.786 1.00 56.17  ?  439 VAL B C   1 
ATOM   8598  O  O   . VAL B 1 450 ? 129.926 175.045 161.571 1.00 56.17  ?  439 VAL B O   1 
ATOM   8599  C  CB  . VAL B 1 450 ? 129.601 177.224 164.080 1.00 56.17  ?  439 VAL B CB  1 
ATOM   8600  C  CG1 . VAL B 1 450 ? 129.989 177.992 162.841 1.00 56.17  ?  439 VAL B CG1 1 
ATOM   8601  C  CG2 . VAL B 1 450 ? 128.501 177.937 164.821 1.00 56.17  ?  439 VAL B CG2 1 
ATOM   8602  N  N   . LEU B 1 451 ? 131.233 174.595 163.338 1.00 53.95  ?  440 LEU B N   1 
ATOM   8603  C  CA  . LEU B 1 451 ? 132.185 173.839 162.532 1.00 53.95  ?  440 LEU B CA  1 
ATOM   8604  C  C   . LEU B 1 451 ? 131.535 172.596 161.943 1.00 53.95  ?  440 LEU B C   1 
ATOM   8605  O  O   . LEU B 1 451 ? 131.743 172.263 160.765 1.00 53.95  ?  440 LEU B O   1 
ATOM   8606  C  CB  . LEU B 1 451 ? 133.391 173.459 163.383 1.00 53.95  ?  440 LEU B CB  1 
ATOM   8607  C  CG  . LEU B 1 451 ? 134.211 174.603 163.966 1.00 53.95  ?  440 LEU B CG  1 
ATOM   8608  C  CD1 . LEU B 1 451 ? 135.197 174.063 164.964 1.00 53.95  ?  440 LEU B CD1 1 
ATOM   8609  C  CD2 . LEU B 1 451 ? 134.925 175.350 162.867 1.00 53.95  ?  440 LEU B CD2 1 
ATOM   8610  N  N   . ALA B 1 452 ? 130.740 171.900 162.755 1.00 54.09  ?  441 ALA B N   1 
ATOM   8611  C  CA  . ALA B 1 452 ? 130.012 170.741 162.261 1.00 54.09  ?  441 ALA B CA  1 
ATOM   8612  C  C   . ALA B 1 452 ? 129.049 171.121 161.143 1.00 54.09  ?  441 ALA B C   1 
ATOM   8613  O  O   . ALA B 1 452 ? 128.934 170.403 160.146 1.00 54.09  ?  441 ALA B O   1 
ATOM   8614  C  CB  . ALA B 1 452 ? 129.275 170.071 163.415 1.00 54.09  ?  441 ALA B CB  1 
ATOM   8615  N  N   . ALA B 1 453 ? 128.361 172.254 161.281 1.00 55.08  ?  442 ALA B N   1 
ATOM   8616  C  CA  . ALA B 1 453 ? 127.428 172.694 160.252 1.00 55.08  ?  442 ALA B CA  1 
ATOM   8617  C  C   . ALA B 1 453 ? 128.149 173.068 158.964 1.00 55.08  ?  442 ALA B C   1 
ATOM   8618  O  O   . ALA B 1 453 ? 127.621 172.854 157.870 1.00 55.08  ?  442 ALA B O   1 
ATOM   8619  C  CB  . ALA B 1 453 ? 126.603 173.869 160.763 1.00 55.08  ?  442 ALA B CB  1 
ATOM   8620  N  N   . LEU B 1 454 ? 129.370 173.584 159.055 1.00 55.78  ?  443 LEU B N   1 
ATOM   8621  C  CA  . LEU B 1 454 ? 130.146 173.950 157.865 1.00 55.78  ?  443 LEU B CA  1 
ATOM   8622  C  C   . LEU B 1 454 ? 130.586 172.728 157.076 1.00 55.78  ?  443 LEU B C   1 
ATOM   8623  O  O   . LEU B 1 454 ? 130.550 172.721 155.860 1.00 55.78  ?  443 LEU B O   1 
ATOM   8624  C  CB  . LEU B 1 454 ? 131.359 174.798 158.230 1.00 55.78  ?  443 LEU B CB  1 
ATOM   8625  C  CG  . LEU B 1 454 ? 131.089 176.247 158.622 1.00 55.78  ?  443 LEU B CG  1 
ATOM   8626  C  CD1 . LEU B 1 454 ? 132.343 176.914 159.151 1.00 55.78  ?  443 LEU B CD1 1 
ATOM   8627  C  CD2 . LEU B 1 454 ? 130.488 177.036 157.476 1.00 55.78  ?  443 LEU B CD2 1 
ATOM   8628  N  N   . ALA B 1 455 ? 131.003 171.689 157.784 1.00 55.84  ?  444 ALA B N   1 
ATOM   8629  C  CA  . ALA B 1 455 ? 131.412 170.428 157.186 1.00 55.84  ?  444 ALA B CA  1 
ATOM   8630  C  C   . ALA B 1 455 ? 130.239 169.761 156.463 1.00 55.84  ?  444 ALA B C   1 
ATOM   8631  O  O   . ALA B 1 455 ? 130.417 169.136 155.429 1.00 55.84  ?  444 ALA B O   1 
ATOM   8632  C  CB  . ALA B 1 455 ? 132.009 169.508 158.229 1.00 55.84  ?  444 ALA B CB  1 
ATOM   8633  N  N   . LEU B 1 456 ? 129.041 169.882 157.030 1.00 56.24  ?  445 LEU B N   1 
ATOM   8634  C  CA  . LEU B 1 456 ? 127.815 169.360 156.447 1.00 56.24  ?  445 LEU B CA  1 
ATOM   8635  C  C   . LEU B 1 456 ? 127.505 170.004 155.104 1.00 56.24  ?  445 LEU B C   1 
ATOM   8636  O  O   . LEU B 1 456 ? 126.980 169.353 154.217 1.00 56.24  ?  445 LEU B O   1 
ATOM   8637  C  CB  . LEU B 1 456 ? 126.634 169.524 157.393 1.00 56.24  ?  445 LEU B CB  1 
ATOM   8638  C  CG  . LEU B 1 456 ? 126.645 168.627 158.623 1.00 56.24  ?  445 LEU B CG  1 
ATOM   8639  C  CD1 . LEU B 1 456 ? 125.406 168.866 159.455 1.00 56.24  ?  445 LEU B CD1 1 
ATOM   8640  C  CD2 . LEU B 1 456 ? 126.787 167.161 158.262 1.00 56.24  ?  445 LEU B CD2 1 
ATOM   8641  N  N   . GLY B 1 457 ? 127.810 171.288 154.964 1.00 57.00  ?  446 GLY B N   1 
ATOM   8642  C  CA  . GLY B 1 457 ? 127.598 172.022 153.735 1.00 57.00  ?  446 GLY B CA  1 
ATOM   8643  C  C   . GLY B 1 457 ? 128.376 171.439 152.575 1.00 57.00  ?  446 GLY B C   1 
ATOM   8644  O  O   . GLY B 1 457 ? 127.890 171.433 151.461 1.00 57.00  ?  446 GLY B O   1 
ATOM   8645  N  N   . ASN B 1 458 ? 129.551 170.896 152.840 1.00 58.77  ?  447 ASN B N   1 
ATOM   8646  C  CA  . ASN B 1 458 ? 130.357 170.311 151.785 1.00 58.77  ?  447 ASN B CA  1 
ATOM   8647  C  C   . ASN B 1 458 ? 129.928 168.926 151.358 1.00 58.77  ?  447 ASN B C   1 
ATOM   8648  O  O   . ASN B 1 458 ? 130.474 168.368 150.427 1.00 58.77  ?  447 ASN B O   1 
ATOM   8649  C  CB  . ASN B 1 458 ? 131.812 170.265 152.207 1.00 58.77  ?  447 ASN B CB  1 
ATOM   8650  C  CG  . ASN B 1 458 ? 132.494 171.591 152.060 1.00 58.77  ?  447 ASN B CG  1 
ATOM   8651  O  OD1 . ASN B 1 458 ? 131.866 172.635 152.113 1.00 58.77  ?  447 ASN B OD1 1 
ATOM   8652  N  ND2 . ASN B 1 458 ? 133.786 171.554 151.867 1.00 58.77  ?  447 ASN B ND2 1 
ATOM   8653  N  N   . LEU B 1 459 ? 128.952 168.363 152.049 1.00 56.71  ?  448 LEU B N   1 
ATOM   8654  C  CA  . LEU B 1 459 ? 128.487 167.015 151.759 1.00 56.71  ?  448 LEU B CA  1 
ATOM   8655  C  C   . LEU B 1 459 ? 127.655 166.881 150.499 1.00 56.71  ?  448 LEU B C   1 
ATOM   8656  O  O   . LEU B 1 459 ? 127.647 165.834 149.881 1.00 56.71  ?  448 LEU B O   1 
ATOM   8657  C  CB  . LEU B 1 459 ? 127.724 166.455 152.949 1.00 56.71  ?  448 LEU B CB  1 
ATOM   8658  C  CG  . LEU B 1 459 ? 128.604 166.008 154.107 1.00 56.71  ?  448 LEU B CG  1 
ATOM   8659  C  CD1 . LEU B 1 459 ? 127.745 165.520 155.247 1.00 56.71  ?  448 LEU B CD1 1 
ATOM   8660  C  CD2 . LEU B 1 459 ? 129.583 164.944 153.667 1.00 56.71  ?  448 LEU B CD2 1 
ATOM   8661  N  N   . LYS B 1 460 ? 126.939 167.936 150.142 1.00 60.57  ?  449 LYS B N   1 
ATOM   8662  C  CA  . LYS B 1 460 ? 126.111 167.959 148.937 1.00 60.57  ?  449 LYS B CA  1 
ATOM   8663  C  C   . LYS B 1 460 ? 126.649 167.317 147.663 1.00 60.57  ?  449 LYS B C   1 
ATOM   8664  O  O   . LYS B 1 460 ? 125.907 166.659 146.965 1.00 60.57  ?  449 LYS B O   1 
ATOM   8665  C  CB  . LYS B 1 460 ? 125.680 169.385 148.613 1.00 60.57  ?  449 LYS B CB  1 
ATOM   8666  C  CG  . LYS B 1 460 ? 124.789 169.472 147.390 1.00 60.57  ?  449 LYS B CG  1 
ATOM   8667  C  CD  . LYS B 1 460 ? 124.980 170.791 146.675 1.00 60.57  ?  449 LYS B CD  1 
ATOM   8668  C  CE  . LYS B 1 460 ? 124.267 170.798 145.338 1.00 60.57  ?  449 LYS B CE  1 
ATOM   8669  N  NZ  . LYS B 1 460 ? 122.804 170.598 145.493 1.00 60.57  1  449 LYS B NZ  1 
ATOM   8670  N  N   . GLY B 1 461 ? 127.912 167.528 147.329 1.00 60.03  ?  450 GLY B N   1 
ATOM   8671  C  CA  . GLY B 1 461 ? 128.435 166.936 146.118 1.00 60.03  ?  450 GLY B CA  1 
ATOM   8672  C  C   . GLY B 1 461 ? 128.502 165.420 146.132 1.00 60.03  ?  450 GLY B C   1 
ATOM   8673  O  O   . GLY B 1 461 ? 128.242 164.787 145.128 1.00 60.03  ?  450 GLY B O   1 
ATOM   8674  N  N   . MET B 1 462 ? 128.841 164.847 147.280 1.00 59.29  ?  451 MET B N   1 
ATOM   8675  C  CA  . MET B 1 462 ? 128.995 163.416 147.473 1.00 59.29  ?  451 MET B CA  1 
ATOM   8676  C  C   . MET B 1 462 ? 127.654 162.744 147.708 1.00 59.29  ?  451 MET B C   1 
ATOM   8677  O  O   . MET B 1 462 ? 127.478 161.581 147.374 1.00 59.29  ?  451 MET B O   1 
ATOM   8678  C  CB  . MET B 1 462 ? 129.940 163.134 148.635 1.00 59.29  ?  451 MET B CB  1 
ATOM   8679  C  CG  . MET B 1 462 ? 131.392 163.471 148.358 1.00 59.29  ?  451 MET B CG  1 
ATOM   8680  S  SD  . MET B 1 462 ? 132.450 163.066 149.759 1.00 59.29  ?  451 MET B SD  1 
ATOM   8681  C  CE  . MET B 1 462 ? 131.713 164.083 151.035 1.00 59.29  ?  451 MET B CE  1 
ATOM   8682  N  N   . LEU B 1 463 ? 126.709 163.473 148.283 1.00 56.35  ?  452 LEU B N   1 
ATOM   8683  C  CA  . LEU B 1 463 ? 125.395 162.908 148.559 1.00 56.35  ?  452 LEU B CA  1 
ATOM   8684  C  C   . LEU B 1 463 ? 124.534 162.848 147.308 1.00 56.35  ?  452 LEU B C   1 
ATOM   8685  O  O   . LEU B 1 463 ? 123.602 162.057 147.234 1.00 56.35  ?  452 LEU B O   1 
ATOM   8686  C  CB  . LEU B 1 463 ? 124.697 163.696 149.665 1.00 56.35  ?  452 LEU B CB  1 
ATOM   8687  C  CG  . LEU B 1 463 ? 125.272 163.459 151.061 1.00 56.35  ?  452 LEU B CG  1 
ATOM   8688  C  CD1 . LEU B 1 463 ? 124.587 164.341 152.092 1.00 56.35  ?  452 LEU B CD1 1 
ATOM   8689  C  CD2 . LEU B 1 463 ? 125.158 161.992 151.442 1.00 56.35  ?  452 LEU B CD2 1 
ATOM   8690  N  N   . MET B 1 464 ? 124.854 163.669 146.320 1.00 59.69  ?  453 MET B N   1 
ATOM   8691  C  CA  . MET B 1 464 ? 124.108 163.655 145.072 1.00 59.69  ?  453 MET B CA  1 
ATOM   8692  C  C   . MET B 1 464 ? 124.554 162.507 144.192 1.00 59.69  ?  453 MET B C   1 
ATOM   8693  O  O   . MET B 1 464 ? 123.953 162.253 143.155 1.00 59.69  ?  453 MET B O   1 
ATOM   8694  C  CB  . MET B 1 464 ? 124.283 164.978 144.337 1.00 59.69  ?  453 MET B CB  1 
ATOM   8695  C  CG  . MET B 1 464 ? 123.590 166.152 145.001 1.00 59.69  ?  453 MET B CG  1 
ATOM   8696  S  SD  . MET B 1 464 ? 123.711 167.650 144.008 1.00 59.69  ?  453 MET B SD  1 
ATOM   8697  C  CE  . MET B 1 464 ? 125.488 167.829 143.892 1.00 59.69  ?  453 MET B CE  1 
ATOM   8698  N  N   . GLN B 1 465 ? 125.601 161.806 144.603 1.00 53.89  ?  454 GLN B N   1 
ATOM   8699  C  CA  . GLN B 1 465 ? 126.086 160.663 143.843 1.00 53.89  ?  454 GLN B CA  1 
ATOM   8700  C  C   . GLN B 1 465 ? 125.139 159.480 143.933 1.00 53.89  ?  454 GLN B C   1 
ATOM   8701  O  O   . GLN B 1 465 ? 125.358 158.470 143.280 1.00 53.89  ?  454 GLN B O   1 
ATOM   8702  C  CB  . GLN B 1 465 ? 127.467 160.261 144.338 1.00 53.89  ?  454 GLN B CB  1 
ATOM   8703  C  CG  . GLN B 1 465 ? 128.513 161.351 144.204 1.00 53.89  ?  454 GLN B CG  1 
ATOM   8704  C  CD  . GLN B 1 465 ? 129.817 160.986 144.880 1.00 53.89  ?  454 GLN B CD  1 
ATOM   8705  O  OE1 . GLN B 1 465 ? 130.829 161.658 144.704 1.00 53.89  ?  454 GLN B OE1 1 
ATOM   8706  N  NE2 . GLN B 1 465 ? 129.798 159.915 145.658 1.00 53.89  ?  454 GLN B NE2 1 
ATOM   8707  N  N   . PHE B 1 466 ? 124.095 159.588 144.743 1.00 50.96  ?  455 PHE B N   1 
ATOM   8708  C  CA  . PHE B 1 466 ? 123.102 158.523 144.821 1.00 50.96  ?  455 PHE B CA  1 
ATOM   8709  C  C   . PHE B 1 466 ? 122.411 158.369 143.477 1.00 50.96  ?  455 PHE B C   1 
ATOM   8710  O  O   . PHE B 1 466 ? 121.886 157.306 143.166 1.00 50.96  ?  455 PHE B O   1 
ATOM   8711  C  CB  . PHE B 1 466 ? 122.074 158.807 145.912 1.00 50.96  ?  455 PHE B CB  1 
ATOM   8712  C  CG  . PHE B 1 466 ? 122.485 158.339 147.275 1.00 50.96  ?  455 PHE B CG  1 
ATOM   8713  C  CD1 . PHE B 1 466 ? 122.636 156.992 147.541 1.00 50.96  ?  455 PHE B CD1 1 
ATOM   8714  C  CD2 . PHE B 1 466 ? 122.695 159.247 148.298 1.00 50.96  ?  455 PHE B CD2 1 
ATOM   8715  C  CE1 . PHE B 1 466 ? 123.006 156.557 148.797 1.00 50.96  ?  455 PHE B CE1 1 
ATOM   8716  C  CE2 . PHE B 1 466 ? 123.063 158.820 149.556 1.00 50.96  ?  455 PHE B CE2 1 
ATOM   8717  C  CZ  . PHE B 1 466 ? 123.219 157.472 149.807 1.00 50.96  ?  455 PHE B CZ  1 
ATOM   8718  N  N   . ALA B 1 467 ? 122.412 159.427 142.678 1.00 53.67  ?  456 ALA B N   1 
ATOM   8719  C  CA  . ALA B 1 467 ? 121.805 159.379 141.357 1.00 53.67  ?  456 ALA B CA  1 
ATOM   8720  C  C   . ALA B 1 467 ? 122.549 158.435 140.438 1.00 53.67  ?  456 ALA B C   1 
ATOM   8721  O  O   . ALA B 1 467 ? 122.002 157.969 139.446 1.00 53.67  ?  456 ALA B O   1 
ATOM   8722  C  CB  . ALA B 1 467 ? 121.776 160.769 140.761 1.00 53.67  ?  456 ALA B CB  1 
ATOM   8723  N  N   . GLU B 1 468 ? 123.798 158.149 140.764 1.00 55.93  ?  457 GLU B N   1 
ATOM   8724  C  CA  . GLU B 1 468 ? 124.610 157.271 139.935 1.00 55.93  ?  457 GLU B CA  1 
ATOM   8725  C  C   . GLU B 1 468 ? 124.019 155.881 139.808 1.00 55.93  ?  457 GLU B C   1 
ATOM   8726  O  O   . GLU B 1 468 ? 124.141 155.252 138.769 1.00 55.93  ?  457 GLU B O   1 
ATOM   8727  C  CB  . GLU B 1 468 ? 126.023 157.180 140.504 1.00 55.93  ?  457 GLU B CB  1 
ATOM   8728  C  CG  . GLU B 1 468 ? 126.869 158.404 140.218 1.00 55.93  ?  457 GLU B CG  1 
ATOM   8729  C  CD  . GLU B 1 468 ? 127.094 158.615 138.733 1.00 55.93  ?  457 GLU B CD  1 
ATOM   8730  O  OE1 . GLU B 1 468 ? 127.054 157.624 137.974 1.00 55.93  ?  457 GLU B OE1 1 
ATOM   8731  O  OE2 . GLU B 1 468 ? 127.320 159.773 138.324 1.00 55.93  -1 457 GLU B OE2 1 
ATOM   8732  N  N   . ILE B 1 469 ? 123.383 155.396 140.862 1.00 54.21  ?  458 ILE B N   1 
ATOM   8733  C  CA  . ILE B 1 469 ? 122.830 154.057 140.832 1.00 54.21  ?  458 ILE B CA  1 
ATOM   8734  C  C   . ILE B 1 469 ? 121.924 153.872 139.627 1.00 54.21  ?  458 ILE B C   1 
ATOM   8735  O  O   . ILE B 1 469 ? 122.105 152.939 138.852 1.00 54.21  ?  458 ILE B O   1 
ATOM   8736  C  CB  . ILE B 1 469 ? 122.031 153.758 142.109 1.00 54.21  ?  458 ILE B CB  1 
ATOM   8737  C  CG1 . ILE B 1 469 ? 122.861 154.109 143.344 1.00 54.21  ?  458 ILE B CG1 1 
ATOM   8738  C  CG2 . ILE B 1 469 ? 121.602 152.300 142.136 1.00 54.21  ?  458 ILE B CG2 1 
ATOM   8739  C  CD1 . ILE B 1 469 ? 122.103 153.962 144.644 1.00 54.21  ?  458 ILE B CD1 1 
ATOM   8740  N  N   . GLY B 1 470 ? 120.962 154.769 139.452 1.00 55.31  ?  459 GLY B N   1 
ATOM   8741  C  CA  . GLY B 1 470 ? 120.051 154.676 138.330 1.00 55.31  ?  459 GLY B CA  1 
ATOM   8742  C  C   . GLY B 1 470 ? 120.746 154.843 137.003 1.00 55.31  ?  459 GLY B C   1 
ATOM   8743  O  O   . GLY B 1 470 ? 120.419 154.163 136.038 1.00 55.31  ?  459 GLY B O   1 
ATOM   8744  N  N   . ARG B 1 471 ? 121.700 155.757 136.941 1.00 55.29  ?  460 ARG B N   1 
ATOM   8745  C  CA  . ARG B 1 471 ? 122.461 155.953 135.719 1.00 55.29  ?  460 ARG B CA  1 
ATOM   8746  C  C   . ARG B 1 471 ? 123.253 154.715 135.352 1.00 55.29  ?  460 ARG B C   1 
ATOM   8747  O  O   . ARG B 1 471 ? 123.223 154.276 134.208 1.00 55.29  ?  460 ARG B O   1 
ATOM   8748  C  CB  . ARG B 1 471 ? 123.414 157.134 135.878 1.00 55.29  ?  460 ARG B CB  1 
ATOM   8749  C  CG  . ARG B 1 471 ? 122.725 158.479 136.010 1.00 55.29  ?  460 ARG B CG  1 
ATOM   8750  C  CD  . ARG B 1 471 ? 123.733 159.612 135.924 1.00 55.29  ?  460 ARG B CD  1 
ATOM   8751  N  NE  . ARG B 1 471 ? 124.452 159.817 137.176 1.00 55.29  ?  460 ARG B NE  1 
ATOM   8752  C  CZ  . ARG B 1 471 ? 124.123 160.735 138.078 1.00 55.29  ?  460 ARG B CZ  1 
ATOM   8753  N  NH1 . ARG B 1 471 ? 124.830 160.859 139.193 1.00 55.29  1  460 ARG B NH1 1 
ATOM   8754  N  NH2 . ARG B 1 471 ? 123.089 161.535 137.861 1.00 55.29  ?  460 ARG B NH2 1 
ATOM   8755  N  N   . LEU B 1 472 ? 123.958 154.146 136.318 1.00 53.03  ?  461 LEU B N   1 
ATOM   8756  C  CA  . LEU B 1 472 ? 124.779 152.977 136.063 1.00 53.03  ?  461 LEU B CA  1 
ATOM   8757  C  C   . LEU B 1 472 ? 123.917 151.775 135.775 1.00 53.03  ?  461 LEU B C   1 
ATOM   8758  O  O   . LEU B 1 472 ? 124.325 150.878 135.050 1.00 53.03  ?  461 LEU B O   1 
ATOM   8759  C  CB  . LEU B 1 472 ? 125.691 152.703 137.255 1.00 53.03  ?  461 LEU B CB  1 
ATOM   8760  C  CG  . LEU B 1 472 ? 126.791 153.718 137.547 1.00 53.03  ?  461 LEU B CG  1 
ATOM   8761  C  CD1 . LEU B 1 472 ? 127.532 153.333 138.817 1.00 53.03  ?  461 LEU B CD1 1 
ATOM   8762  C  CD2 . LEU B 1 472 ? 127.746 153.802 136.369 1.00 53.03  ?  461 LEU B CD2 1 
ATOM   8763  N  N   . TRP B 1 473 ? 122.720 151.750 136.338 1.00 53.85  ?  462 TRP B N   1 
ATOM   8764  C  CA  . TRP B 1 473 ? 121.808 150.651 136.092 1.00 53.85  ?  462 TRP B CA  1 
ATOM   8765  C  C   . TRP B 1 473 ? 121.466 150.602 134.625 1.00 53.85  ?  462 TRP B C   1 
ATOM   8766  O  O   . TRP B 1 473 ? 121.447 149.531 134.023 1.00 53.85  ?  462 TRP B O   1 
ATOM   8767  C  CB  . TRP B 1 473 ? 120.540 150.821 136.913 1.00 53.85  ?  462 TRP B CB  1 
ATOM   8768  C  CG  . TRP B 1 473 ? 119.516 149.782 136.621 1.00 53.85  ?  462 TRP B CG  1 
ATOM   8769  C  CD1 . TRP B 1 473 ? 118.465 149.887 135.761 1.00 53.85  ?  462 TRP B CD1 1 
ATOM   8770  C  CD2 . TRP B 1 473 ? 119.449 148.468 137.181 1.00 53.85  ?  462 TRP B CD2 1 
ATOM   8771  N  NE1 . TRP B 1 473 ? 117.743 148.720 135.754 1.00 53.85  ?  462 TRP B NE1 1 
ATOM   8772  C  CE2 . TRP B 1 473 ? 118.327 147.833 136.619 1.00 53.85  ?  462 TRP B CE2 1 
ATOM   8773  C  CE3 . TRP B 1 473 ? 120.227 147.769 138.106 1.00 53.85  ?  462 TRP B CE3 1 
ATOM   8774  C  CZ2 . TRP B 1 473 ? 117.963 146.532 136.950 1.00 53.85  ?  462 TRP B CZ2 1 
ATOM   8775  C  CZ3 . TRP B 1 473 ? 119.864 146.479 138.434 1.00 53.85  ?  462 TRP B CZ3 1 
ATOM   8776  C  CH2 . TRP B 1 473 ? 118.743 145.873 137.858 1.00 53.85  ?  462 TRP B CH2 1 
ATOM   8777  N  N   . ARG B 1 474 ? 121.187 151.758 134.040 1.00 56.35  ?  463 ARG B N   1 
ATOM   8778  C  CA  . ARG B 1 474 ? 120.913 151.819 132.610 1.00 56.35  ?  463 ARG B CA  1 
ATOM   8779  C  C   . ARG B 1 474 ? 122.144 151.458 131.788 1.00 56.35  ?  463 ARG B C   1 
ATOM   8780  O  O   . ARG B 1 474 ? 122.038 150.743 130.789 1.00 56.35  ?  463 ARG B O   1 
ATOM   8781  C  CB  . ARG B 1 474 ? 120.404 153.203 132.232 1.00 56.35  ?  463 ARG B CB  1 
ATOM   8782  C  CG  . ARG B 1 474 ? 118.993 153.465 132.681 1.00 56.35  ?  463 ARG B CG  1 
ATOM   8783  C  CD  . ARG B 1 474 ? 118.478 154.780 132.138 1.00 56.35  ?  463 ARG B CD  1 
ATOM   8784  N  NE  . ARG B 1 474 ? 119.168 155.923 132.722 1.00 56.35  ?  463 ARG B NE  1 
ATOM   8785  C  CZ  . ARG B 1 474 ? 118.883 156.435 133.913 1.00 56.35  ?  463 ARG B CZ  1 
ATOM   8786  N  NH1 . ARG B 1 474 ? 119.558 157.481 134.367 1.00 56.35  1  463 ARG B NH1 1 
ATOM   8787  N  NH2 . ARG B 1 474 ? 117.924 155.899 134.653 1.00 56.35  ?  463 ARG B NH2 1 
ATOM   8788  N  N   . LYS B 1 475 ? 123.321 151.932 132.194 1.00 54.81  ?  464 LYS B N   1 
ATOM   8789  C  CA  . LYS B 1 475 ? 124.521 151.747 131.383 1.00 54.81  ?  464 LYS B CA  1 
ATOM   8790  C  C   . LYS B 1 475 ? 125.108 150.350 131.527 1.00 54.81  ?  464 LYS B C   1 
ATOM   8791  O  O   . LYS B 1 475 ? 125.282 149.634 130.539 1.00 54.81  ?  464 LYS B O   1 
ATOM   8792  C  CB  . LYS B 1 475 ? 125.577 152.782 131.758 1.00 54.81  ?  464 LYS B CB  1 
ATOM   8793  C  CG  . LYS B 1 475 ? 125.291 154.174 131.308 1.00 54.81  ?  464 LYS B CG  1 
ATOM   8794  C  CD  . LYS B 1 475 ? 126.267 155.106 131.968 1.00 54.81  ?  464 LYS B CD  1 
ATOM   8795  C  CE  . LYS B 1 475 ? 125.879 156.545 131.775 1.00 54.81  ?  464 LYS B CE  1 
ATOM   8796  N  NZ  . LYS B 1 475 ? 126.732 157.423 132.611 1.00 54.81  1  464 LYS B NZ  1 
ATOM   8797  N  N   . ASP B 1 476 ? 125.452 149.957 132.750 1.00 53.34  ?  465 ASP B N   1 
ATOM   8798  C  CA  . ASP B 1 476 ? 126.235 148.751 132.990 1.00 53.34  ?  465 ASP B CA  1 
ATOM   8799  C  C   . ASP B 1 476 ? 125.893 148.203 134.363 1.00 53.34  ?  465 ASP B C   1 
ATOM   8800  O  O   . ASP B 1 476 ? 126.216 148.827 135.374 1.00 53.34  ?  465 ASP B O   1 
ATOM   8801  C  CB  . ASP B 1 476 ? 127.731 149.053 132.895 1.00 53.34  ?  465 ASP B CB  1 
ATOM   8802  C  CG  . ASP B 1 476 ? 128.580 147.810 132.925 1.00 53.34  ?  465 ASP B CG  1 
ATOM   8803  O  OD1 . ASP B 1 476 ? 128.035 146.707 132.745 1.00 53.34  ?  465 ASP B OD1 1 
ATOM   8804  O  OD2 . ASP B 1 476 ? 129.798 147.932 133.125 1.00 53.34  -1 465 ASP B OD2 1 
ATOM   8805  N  N   . LYS B 1 477 ? 125.264 147.033 134.403 1.00 50.34  ?  466 LYS B N   1 
ATOM   8806  C  CA  . LYS B 1 477 ? 124.803 146.480 135.667 1.00 50.34  ?  466 LYS B CA  1 
ATOM   8807  C  C   . LYS B 1 477 ? 125.934 145.954 136.536 1.00 50.34  ?  466 LYS B C   1 
ATOM   8808  O  O   . LYS B 1 477 ? 125.759 145.857 137.752 1.00 50.34  ?  466 LYS B O   1 
ATOM   8809  C  CB  . LYS B 1 477 ? 123.786 145.371 135.415 1.00 50.34  ?  466 LYS B CB  1 
ATOM   8810  C  CG  . LYS B 1 477 ? 122.664 145.784 134.501 1.00 50.34  ?  466 LYS B CG  1 
ATOM   8811  C  CD  . LYS B 1 477 ? 121.332 145.714 135.194 1.00 50.34  ?  466 LYS B CD  1 
ATOM   8812  C  CE  . LYS B 1 477 ? 120.195 145.783 134.200 1.00 50.34  ?  466 LYS B CE  1 
ATOM   8813  N  NZ  . LYS B 1 477 ? 120.315 146.952 133.301 1.00 50.34  1  466 LYS B NZ  1 
ATOM   8814  N  N   . TYR B 1 478 ? 127.085 145.621 135.957 1.00 48.92  ?  467 TYR B N   1 
ATOM   8815  C  CA  . TYR B 1 478 ? 128.228 145.244 136.780 1.00 48.92  ?  467 TYR B CA  1 
ATOM   8816  C  C   . TYR B 1 478 ? 128.766 146.440 137.550 1.00 48.92  ?  467 TYR B C   1 
ATOM   8817  O  O   . TYR B 1 478 ? 129.150 146.316 138.716 1.00 48.92  ?  467 TYR B O   1 
ATOM   8818  C  CB  . TYR B 1 478 ? 129.324 144.627 135.920 1.00 48.92  ?  467 TYR B CB  1 
ATOM   8819  C  CG  . TYR B 1 478 ? 128.952 143.303 135.315 1.00 48.92  ?  467 TYR B CG  1 
ATOM   8820  C  CD1 . TYR B 1 478 ? 128.900 142.159 136.086 1.00 48.92  ?  467 TYR B CD1 1 
ATOM   8821  C  CD2 . TYR B 1 478 ? 128.645 143.201 133.973 1.00 48.92  ?  467 TYR B CD2 1 
ATOM   8822  C  CE1 . TYR B 1 478 ? 128.553 140.955 135.536 1.00 48.92  ?  467 TYR B CE1 1 
ATOM   8823  C  CE2 . TYR B 1 478 ? 128.303 142.004 133.417 1.00 48.92  ?  467 TYR B CE2 1 
ATOM   8824  C  CZ  . TYR B 1 478 ? 128.256 140.884 134.201 1.00 48.92  ?  467 TYR B CZ  1 
ATOM   8825  O  OH  . TYR B 1 478 ? 127.912 139.684 133.638 1.00 48.92  ?  467 TYR B OH  1 
ATOM   8826  N  N   . ASP B 1 479 ? 128.773 147.616 136.929 1.00 50.27  ?  468 ASP B N   1 
ATOM   8827  C  CA  . ASP B 1 479 ? 129.218 148.809 137.634 1.00 50.27  ?  468 ASP B CA  1 
ATOM   8828  C  C   . ASP B 1 479 ? 128.177 149.282 138.640 1.00 50.27  ?  468 ASP B C   1 
ATOM   8829  O  O   . ASP B 1 479 ? 128.528 149.812 139.696 1.00 50.27  ?  468 ASP B O   1 
ATOM   8830  C  CB  . ASP B 1 479 ? 129.555 149.908 136.634 1.00 50.27  ?  468 ASP B CB  1 
ATOM   8831  C  CG  . ASP B 1 479 ? 130.939 149.750 136.050 1.00 50.27  ?  468 ASP B CG  1 
ATOM   8832  O  OD1 . ASP B 1 479 ? 131.915 149.699 136.822 1.00 50.27  ?  468 ASP B OD1 1 
ATOM   8833  O  OD2 . ASP B 1 479 ? 131.060 149.671 134.815 1.00 50.27  -1 468 ASP B OD2 1 
ATOM   8834  N  N   . CYS B 1 480 ? 126.894 149.092 138.339 1.00 49.31  ?  469 CYS B N   1 
ATOM   8835  C  CA  . CYS B 1 480 ? 125.862 149.357 139.334 1.00 49.31  ?  469 CYS B CA  1 
ATOM   8836  C  C   . CYS B 1 480 ? 126.019 148.435 140.533 1.00 49.31  ?  469 CYS B C   1 
ATOM   8837  O  O   . CYS B 1 480 ? 125.852 148.858 141.682 1.00 49.31  ?  469 CYS B O   1 
ATOM   8838  C  CB  . CYS B 1 480 ? 124.480 149.196 138.708 1.00 49.31  ?  469 CYS B CB  1 
ATOM   8839  S  SG  . CYS B 1 480 ? 123.113 149.637 139.776 1.00 49.31  ?  469 CYS B SG  1 
ATOM   8840  N  N   . LEU B 1 481 ? 126.353 147.173 140.283 1.00 46.98  ?  470 LEU B N   1 
ATOM   8841  C  CA  . LEU B 1 481 ? 126.607 146.240 141.368 1.00 46.98  ?  470 LEU B CA  1 
ATOM   8842  C  C   . LEU B 1 481 ? 127.819 146.660 142.183 1.00 46.98  ?  470 LEU B C   1 
ATOM   8843  O  O   . LEU B 1 481 ? 127.810 146.562 143.411 1.00 46.98  ?  470 LEU B O   1 
ATOM   8844  C  CB  . LEU B 1 481 ? 126.796 144.838 140.800 1.00 46.98  ?  470 LEU B CB  1 
ATOM   8845  C  CG  . LEU B 1 481 ? 126.937 143.682 141.780 1.00 46.98  ?  470 LEU B CG  1 
ATOM   8846  C  CD1 . LEU B 1 481 ? 125.657 143.480 142.555 1.00 46.98  ?  470 LEU B CD1 1 
ATOM   8847  C  CD2 . LEU B 1 481 ? 127.314 142.432 141.030 1.00 46.98  ?  470 LEU B CD2 1 
ATOM   8848  N  N   . ILE B 1 482 ? 128.874 147.125 141.515 1.00 45.55  ?  471 ILE B N   1 
ATOM   8849  C  CA  . ILE B 1 482 ? 130.054 147.608 142.227 1.00 45.55  ?  471 ILE B CA  1 
ATOM   8850  C  C   . ILE B 1 482 ? 129.691 148.789 143.115 1.00 45.55  ?  471 ILE B C   1 
ATOM   8851  O  O   . ILE B 1 482 ? 130.083 148.849 144.281 1.00 45.55  ?  471 ILE B O   1 
ATOM   8852  C  CB  . ILE B 1 482 ? 131.171 147.975 141.236 1.00 45.55  ?  471 ILE B CB  1 
ATOM   8853  C  CG1 . ILE B 1 482 ? 131.766 146.723 140.607 1.00 45.55  ?  471 ILE B CG1 1 
ATOM   8854  C  CG2 . ILE B 1 482 ? 132.256 148.758 141.929 1.00 45.55  ?  471 ILE B CG2 1 
ATOM   8855  C  CD1 . ILE B 1 482 ? 132.728 147.022 139.498 1.00 45.55  ?  471 ILE B CD1 1 
ATOM   8856  N  N   . TRP B 1 483 ? 128.933 149.743 142.574 1.00 45.57  ?  472 TRP B N   1 
ATOM   8857  C  CA  . TRP B 1 483 ? 128.487 150.892 143.354 1.00 45.57  ?  472 TRP B CA  1 
ATOM   8858  C  C   . TRP B 1 483 ? 127.723 150.457 144.595 1.00 45.57  ?  472 TRP B C   1 
ATOM   8859  O  O   . TRP B 1 483 ? 128.044 150.869 145.715 1.00 45.57  ?  472 TRP B O   1 
ATOM   8860  C  CB  . TRP B 1 483 ? 127.612 151.796 142.488 1.00 45.57  ?  472 TRP B CB  1 
ATOM   8861  C  CG  . TRP B 1 483 ? 127.478 153.205 142.974 1.00 45.57  ?  472 TRP B CG  1 
ATOM   8862  C  CD1 . TRP B 1 483 ? 128.064 154.296 142.439 1.00 45.57  ?  472 TRP B CD1 1 
ATOM   8863  C  CD2 . TRP B 1 483 ? 126.693 153.673 144.076 1.00 45.57  ?  472 TRP B CD2 1 
ATOM   8864  N  NE1 . TRP B 1 483 ? 127.708 155.415 143.132 1.00 45.57  ?  472 TRP B NE1 1 
ATOM   8865  C  CE2 . TRP B 1 483 ? 126.867 155.059 144.147 1.00 45.57  ?  472 TRP B CE2 1 
ATOM   8866  C  CE3 . TRP B 1 483 ? 125.866 153.053 145.013 1.00 45.57  ?  472 TRP B CE3 1 
ATOM   8867  C  CZ2 . TRP B 1 483 ? 126.248 155.836 145.110 1.00 45.57  ?  472 TRP B CZ2 1 
ATOM   8868  C  CZ3 . TRP B 1 483 ? 125.259 153.824 145.968 1.00 45.57  ?  472 TRP B CZ3 1 
ATOM   8869  C  CH2 . TRP B 1 483 ? 125.450 155.199 146.011 1.00 45.57  ?  472 TRP B CH2 1 
ATOM   8870  N  N   . ILE B 1 484 ? 126.699 149.627 144.410 1.00 47.14  ?  473 ILE B N   1 
ATOM   8871  C  CA  . ILE B 1 484 ? 125.824 149.255 145.515 1.00 47.14  ?  473 ILE B CA  1 
ATOM   8872  C  C   . ILE B 1 484 ? 126.579 148.446 146.559 1.00 47.14  ?  473 ILE B C   1 
ATOM   8873  O  O   . ILE B 1 484 ? 126.420 148.668 147.764 1.00 47.14  ?  473 ILE B O   1 
ATOM   8874  C  CB  . ILE B 1 484 ? 124.598 148.499 144.977 1.00 47.14  ?  473 ILE B CB  1 
ATOM   8875  C  CG1 . ILE B 1 484 ? 123.719 149.444 144.165 1.00 47.14  ?  473 ILE B CG1 1 
ATOM   8876  C  CG2 . ILE B 1 484 ? 123.810 147.883 146.105 1.00 47.14  ?  473 ILE B CG2 1 
ATOM   8877  C  CD1 . ILE B 1 484 ? 122.658 148.749 143.375 1.00 47.14  ?  473 ILE B CD1 1 
ATOM   8878  N  N   . MET B 1 485 ? 127.417 147.505 146.127 1.00 49.24  ?  474 MET B N   1 
ATOM   8879  C  CA  . MET B 1 485 ? 128.146 146.697 147.091 1.00 49.24  ?  474 MET B CA  1 
ATOM   8880  C  C   . MET B 1 485 ? 129.207 147.505 147.814 1.00 49.24  ?  474 MET B C   1 
ATOM   8881  O  O   . MET B 1 485 ? 129.445 147.270 148.996 1.00 49.24  ?  474 MET B O   1 
ATOM   8882  C  CB  . MET B 1 485 ? 128.776 145.486 146.411 1.00 49.24  ?  474 MET B CB  1 
ATOM   8883  C  CG  . MET B 1 485 ? 127.774 144.452 145.943 1.00 49.24  ?  474 MET B CG  1 
ATOM   8884  S  SD  . MET B 1 485 ? 126.466 144.088 147.120 1.00 49.24  ?  474 MET B SD  1 
ATOM   8885  C  CE  . MET B 1 485 ? 127.388 143.290 148.421 1.00 49.24  ?  474 MET B CE  1 
ATOM   8886  N  N   . THR B 1 486 ? 129.848 148.460 147.139 1.00 46.33  ?  475 THR B N   1 
ATOM   8887  C  CA  . THR B 1 486 ? 130.783 149.342 147.823 1.00 46.33  ?  475 THR B CA  1 
ATOM   8888  C  C   . THR B 1 486 ? 130.069 150.167 148.879 1.00 46.33  ?  475 THR B C   1 
ATOM   8889  O  O   . THR B 1 486 ? 130.555 150.308 150.005 1.00 46.33  ?  475 THR B O   1 
ATOM   8890  C  CB  . THR B 1 486 ? 131.477 150.254 146.816 1.00 46.33  ?  475 THR B CB  1 
ATOM   8891  O  OG1 . THR B 1 486 ? 132.061 149.460 145.783 1.00 46.33  ?  475 THR B OG1 1 
ATOM   8892  C  CG2 . THR B 1 486 ? 132.554 151.055 147.487 1.00 46.33  ?  475 THR B CG2 1 
ATOM   8893  N  N   . PHE B 1 487 ? 128.909 150.720 148.531 1.00 45.34  ?  476 PHE B N   1 
ATOM   8894  C  CA  . PHE B 1 487 ? 128.142 151.489 149.499 1.00 45.34  ?  476 PHE B CA  1 
ATOM   8895  C  C   . PHE B 1 487 ? 127.778 150.638 150.707 1.00 45.34  ?  476 PHE B C   1 
ATOM   8896  O  O   . PHE B 1 487 ? 127.946 151.063 151.852 1.00 45.34  ?  476 PHE B O   1 
ATOM   8897  C  CB  . PHE B 1 487 ? 126.891 152.058 148.838 1.00 45.34  ?  476 PHE B CB  1 
ATOM   8898  C  CG  . PHE B 1 487 ? 126.084 152.937 149.736 1.00 45.34  ?  476 PHE B CG  1 
ATOM   8899  C  CD1 . PHE B 1 487 ? 126.336 154.283 149.808 1.00 45.34  ?  476 PHE B CD1 1 
ATOM   8900  C  CD2 . PHE B 1 487 ? 125.072 152.414 150.511 1.00 45.34  ?  476 PHE B CD2 1 
ATOM   8901  C  CE1 . PHE B 1 487 ? 125.603 155.086 150.631 1.00 45.34  ?  476 PHE B CE1 1 
ATOM   8902  C  CE2 . PHE B 1 487 ? 124.339 153.218 151.336 1.00 45.34  ?  476 PHE B CE2 1 
ATOM   8903  C  CZ  . PHE B 1 487 ? 124.605 154.554 151.394 1.00 45.34  ?  476 PHE B CZ  1 
ATOM   8904  N  N   . ILE B 1 488 ? 127.286 149.423 150.470 1.00 47.07  ?  477 ILE B N   1 
ATOM   8905  C  CA  . ILE B 1 488 ? 126.863 148.567 151.572 1.00 47.07  ?  477 ILE B CA  1 
ATOM   8906  C  C   . ILE B 1 488 ? 128.055 148.152 152.426 1.00 47.07  ?  477 ILE B C   1 
ATOM   8907  O  O   . ILE B 1 488 ? 127.976 148.150 153.656 1.00 47.07  ?  477 ILE B O   1 
ATOM   8908  C  CB  . ILE B 1 488 ? 126.095 147.348 151.035 1.00 47.07  ?  477 ILE B CB  1 
ATOM   8909  C  CG1 . ILE B 1 488 ? 124.747 147.779 150.473 1.00 47.07  ?  477 ILE B CG1 1 
ATOM   8910  C  CG2 . ILE B 1 488 ? 125.883 146.327 152.120 1.00 47.07  ?  477 ILE B CG2 1 
ATOM   8911  C  CD1 . ILE B 1 488 ? 124.081 146.729 149.649 1.00 47.07  ?  477 ILE B CD1 1 
ATOM   8912  N  N   . PHE B 1 489 ? 129.175 147.796 151.798 1.00 48.20  ?  478 PHE B N   1 
ATOM   8913  C  CA  . PHE B 1 489 ? 130.352 147.387 152.553 1.00 48.20  ?  478 PHE B CA  1 
ATOM   8914  C  C   . PHE B 1 489 ? 130.896 148.531 153.392 1.00 48.20  ?  478 PHE B C   1 
ATOM   8915  O  O   . PHE B 1 489 ? 131.373 148.318 154.508 1.00 48.20  ?  478 PHE B O   1 
ATOM   8916  C  CB  . PHE B 1 489 ? 131.437 146.879 151.609 1.00 48.20  ?  478 PHE B CB  1 
ATOM   8917  C  CG  . PHE B 1 489 ? 131.203 145.502 151.100 1.00 48.20  ?  478 PHE B CG  1 
ATOM   8918  C  CD1 . PHE B 1 489 ? 130.471 144.594 151.832 1.00 48.20  ?  478 PHE B CD1 1 
ATOM   8919  C  CD2 . PHE B 1 489 ? 131.721 145.111 149.881 1.00 48.20  ?  478 PHE B CD2 1 
ATOM   8920  C  CE1 . PHE B 1 489 ? 130.262 143.326 151.357 1.00 48.20  ?  478 PHE B CE1 1 
ATOM   8921  C  CE2 . PHE B 1 489 ? 131.513 143.850 149.404 1.00 48.20  ?  478 PHE B CE2 1 
ATOM   8922  C  CZ  . PHE B 1 489 ? 130.786 142.955 150.141 1.00 48.20  ?  478 PHE B CZ  1 
ATOM   8923  N  N   . THR B 1 490 ? 130.851 149.751 152.869 1.00 47.47  ?  479 THR B N   1 
ATOM   8924  C  CA  . THR B 1 490 ? 131.364 150.885 153.618 1.00 47.47  ?  479 THR B CA  1 
ATOM   8925  C  C   . THR B 1 490 ? 130.407 151.334 154.712 1.00 47.47  ?  479 THR B C   1 
ATOM   8926  O  O   . THR B 1 490 ? 130.854 151.845 155.739 1.00 47.47  ?  479 THR B O   1 
ATOM   8927  C  CB  . THR B 1 490 ? 131.669 152.037 152.664 1.00 47.47  ?  479 THR B CB  1 
ATOM   8928  O  OG1 . THR B 1 490 ? 132.370 151.533 151.526 1.00 47.47  ?  479 THR B OG1 1 
ATOM   8929  C  CG2 . THR B 1 490 ? 132.514 153.086 153.335 1.00 47.47  ?  479 THR B CG2 1 
ATOM   8930  N  N   . ILE B 1 491 ? 129.106 151.151 154.528 1.00 48.50  ?  480 ILE B N   1 
ATOM   8931  C  CA  . ILE B 1 491 ? 128.157 151.490 155.579 1.00 48.50  ?  480 ILE B CA  1 
ATOM   8932  C  C   . ILE B 1 491 ? 128.193 150.460 156.697 1.00 48.50  ?  480 ILE B C   1 
ATOM   8933  O  O   . ILE B 1 491 ? 128.223 150.808 157.880 1.00 48.50  ?  480 ILE B O   1 
ATOM   8934  C  CB  . ILE B 1 491 ? 126.741 151.637 154.992 1.00 48.50  ?  480 ILE B CB  1 
ATOM   8935  C  CG1 . ILE B 1 491 ? 126.609 152.955 154.236 1.00 48.50  ?  480 ILE B CG1 1 
ATOM   8936  C  CG2 . ILE B 1 491 ? 125.706 151.553 156.084 1.00 48.50  ?  480 ILE B CG2 1 
ATOM   8937  C  CD1 . ILE B 1 491 ? 126.705 154.159 155.103 1.00 48.50  ?  480 ILE B CD1 1 
ATOM   8938  N  N   . VAL B 1 492 ? 128.208 149.179 156.348 1.00 50.55  ?  481 VAL B N   1 
ATOM   8939  C  CA  . VAL B 1 492 ? 128.170 148.129 157.356 1.00 50.55  ?  481 VAL B CA  1 
ATOM   8940  C  C   . VAL B 1 492 ? 129.536 147.964 158.001 1.00 50.55  ?  481 VAL B C   1 
ATOM   8941  O  O   . VAL B 1 492 ? 129.694 148.186 159.203 1.00 50.55  ?  481 VAL B O   1 
ATOM   8942  C  CB  . VAL B 1 492 ? 127.672 146.810 156.747 1.00 50.55  ?  481 VAL B CB  1 
ATOM   8943  C  CG1 . VAL B 1 492 ? 127.863 145.682 157.722 1.00 50.55  ?  481 VAL B CG1 1 
ATOM   8944  C  CG2 . VAL B 1 492 ? 126.218 146.937 156.377 1.00 50.55  ?  481 VAL B CG2 1 
ATOM   8945  N  N   . LEU B 1 493 ? 130.519 147.570 157.213 1.00 51.57  ?  482 LEU B N   1 
ATOM   8946  C  CA  . LEU B 1 493 ? 131.860 147.523 157.731 1.00 51.57  ?  482 LEU B CA  1 
ATOM   8947  C  C   . LEU B 1 493 ? 132.218 148.982 157.684 1.00 51.57  ?  482 LEU B C   1 
ATOM   8948  O  O   . LEU B 1 493 ? 131.385 149.809 157.337 1.00 51.57  ?  482 LEU B O   1 
ATOM   8949  C  CB  . LEU B 1 493 ? 132.762 146.706 156.832 1.00 51.57  ?  482 LEU B CB  1 
ATOM   8950  C  CG  . LEU B 1 493 ? 132.200 145.370 156.348 1.00 51.57  ?  482 LEU B CG  1 
ATOM   8951  C  CD1 . LEU B 1 493 ? 133.147 144.709 155.359 1.00 51.57  ?  482 LEU B CD1 1 
ATOM   8952  C  CD2 . LEU B 1 493 ? 131.909 144.452 157.522 1.00 51.57  ?  482 LEU B CD2 1 
ATOM   8953  N  N   . GLY B 1 494 ? 133.433 149.346 158.017 1.00 53.63  ?  483 GLY B N   1 
ATOM   8954  C  CA  . GLY B 1 494 ? 133.728 150.758 158.042 1.00 53.63  ?  483 GLY B CA  1 
ATOM   8955  C  C   . GLY B 1 494 ? 134.341 151.285 156.780 1.00 53.63  ?  483 GLY B C   1 
ATOM   8956  O  O   . GLY B 1 494 ? 134.223 150.677 155.723 1.00 53.63  ?  483 GLY B O   1 
ATOM   8957  N  N   . LEU B 1 495 ? 135.002 152.426 156.886 1.00 51.44  ?  484 LEU B N   1 
ATOM   8958  C  CA  . LEU B 1 495 ? 135.660 153.010 155.737 1.00 51.44  ?  484 LEU B CA  1 
ATOM   8959  C  C   . LEU B 1 495 ? 136.852 152.170 155.299 1.00 51.44  ?  484 LEU B C   1 
ATOM   8960  O  O   . LEU B 1 495 ? 137.024 151.916 154.113 1.00 51.44  ?  484 LEU B O   1 
ATOM   8961  C  CB  . LEU B 1 495 ? 136.083 154.440 156.064 1.00 51.44  ?  484 LEU B CB  1 
ATOM   8962  C  CG  . LEU B 1 495 ? 134.945 155.387 156.451 1.00 51.44  ?  484 LEU B CG  1 
ATOM   8963  C  CD1 . LEU B 1 495 ? 135.473 156.716 156.964 1.00 51.44  ?  484 LEU B CD1 1 
ATOM   8964  C  CD2 . LEU B 1 495 ? 134.005 155.598 155.278 1.00 51.44  ?  484 LEU B CD2 1 
ATOM   8965  N  N   . GLY B 1 496 ? 137.671 151.734 156.246 1.00 52.78  ?  485 GLY B N   1 
ATOM   8966  C  CA  . GLY B 1 496 ? 138.837 150.938 155.912 1.00 52.78  ?  485 GLY B CA  1 
ATOM   8967  C  C   . GLY B 1 496 ? 138.532 149.526 155.464 1.00 52.78  ?  485 GLY B C   1 
ATOM   8968  O  O   . GLY B 1 496 ? 138.970 149.099 154.398 1.00 52.78  ?  485 GLY B O   1 
ATOM   8969  N  N   . LEU B 1 497 ? 137.767 148.799 156.265 1.00 54.07  ?  486 LEU B N   1 
ATOM   8970  C  CA  . LEU B 1 497 ? 137.416 147.430 155.920 1.00 54.07  ?  486 LEU B CA  1 
ATOM   8971  C  C   . LEU B 1 497 ? 136.454 147.394 154.749 1.00 54.07  ?  486 LEU B C   1 
ATOM   8972  O  O   . LEU B 1 497 ? 136.536 146.509 153.904 1.00 54.07  ?  486 LEU B O   1 
ATOM   8973  C  CB  . LEU B 1 497 ? 136.819 146.709 157.123 1.00 54.07  ?  486 LEU B CB  1 
ATOM   8974  C  CG  . LEU B 1 497 ? 137.671 145.583 157.700 1.00 54.07  ?  486 LEU B CG  1 
ATOM   8975  C  CD1 . LEU B 1 497 ? 136.886 144.840 158.768 1.00 54.07  ?  486 LEU B CD1 1 
ATOM   8976  C  CD2 . LEU B 1 497 ? 138.089 144.632 156.590 1.00 54.07  ?  486 LEU B CD2 1 
ATOM   8977  N  N   . GLY B 1 498 ? 135.545 148.354 154.691 1.00 50.43  ?  487 GLY B N   1 
ATOM   8978  C  CA  . GLY B 1 498 ? 134.624 148.418 153.580 1.00 50.43  ?  487 GLY B CA  1 
ATOM   8979  C  C   . GLY B 1 498 ? 135.370 148.563 152.278 1.00 50.43  ?  487 GLY B C   1 
ATOM   8980  O  O   . GLY B 1 498 ? 135.016 147.935 151.292 1.00 50.43  ?  487 GLY B O   1 
ATOM   8981  N  N   . LEU B 1 499 ? 136.414 149.380 152.272 1.00 48.97  ?  488 LEU B N   1 
ATOM   8982  C  CA  . LEU B 1 499 ? 137.191 149.594 151.063 1.00 48.97  ?  488 LEU B CA  1 
ATOM   8983  C  C   . LEU B 1 499 ? 137.887 148.321 150.629 1.00 48.97  ?  488 LEU B C   1 
ATOM   8984  O  O   . LEU B 1 499 ? 137.895 147.988 149.452 1.00 48.97  ?  488 LEU B O   1 
ATOM   8985  C  CB  . LEU B 1 499 ? 138.222 150.702 151.273 1.00 48.97  ?  488 LEU B CB  1 
ATOM   8986  C  CG  . LEU B 1 499 ? 138.968 151.129 150.011 1.00 48.97  ?  488 LEU B CG  1 
ATOM   8987  C  CD1 . LEU B 1 499 ? 138.008 151.798 149.041 1.00 48.97  ?  488 LEU B CD1 1 
ATOM   8988  C  CD2 . LEU B 1 499 ? 140.117 152.060 150.358 1.00 48.97  ?  488 LEU B CD2 1 
ATOM   8989  N  N   . ALA B 1 500 ? 138.473 147.609 151.578 1.00 47.92  ?  489 ALA B N   1 
ATOM   8990  C  CA  . ALA B 1 500 ? 139.147 146.364 151.257 1.00 47.92  ?  489 ALA B CA  1 
ATOM   8991  C  C   . ALA B 1 500 ? 138.176 145.357 150.672 1.00 47.92  ?  489 ALA B C   1 
ATOM   8992  O  O   . ALA B 1 500 ? 138.497 144.673 149.708 1.00 47.92  ?  489 ALA B O   1 
ATOM   8993  C  CB  . ALA B 1 500 ? 139.812 145.801 152.497 1.00 47.92  ?  489 ALA B CB  1 
ATOM   8994  N  N   . ALA B 1 501 ? 136.990 145.262 151.252 1.00 47.17  ?  490 ALA B N   1 
ATOM   8995  C  CA  . ALA B 1 501 ? 135.992 144.322 150.772 1.00 47.17  ?  490 ALA B CA  1 
ATOM   8996  C  C   . ALA B 1 501 ? 135.461 144.760 149.432 1.00 47.17  ?  490 ALA B C   1 
ATOM   8997  O  O   . ALA B 1 501 ? 135.129 143.936 148.589 1.00 47.17  ?  490 ALA B O   1 
ATOM   8998  C  CB  . ALA B 1 501 ? 134.858 144.219 151.773 1.00 47.17  ?  490 ALA B CB  1 
ATOM   8999  N  N   . SER B 1 502 ? 135.380 146.064 149.233 1.00 46.75  ?  491 SER B N   1 
ATOM   9000  C  CA  . SER B 1 502 ? 134.870 146.602 147.980 1.00 46.75  ?  491 SER B CA  1 
ATOM   9001  C  C   . SER B 1 502 ? 135.852 146.384 146.841 1.00 46.75  ?  491 SER B C   1 
ATOM   9002  O  O   . SER B 1 502 ? 135.446 146.080 145.718 1.00 46.75  ?  491 SER B O   1 
ATOM   9003  C  CB  . SER B 1 502 ? 134.569 148.081 148.150 1.00 46.75  ?  491 SER B CB  1 
ATOM   9004  O  OG  . SER B 1 502 ? 133.666 148.275 149.214 1.00 46.75  ?  491 SER B OG  1 
ATOM   9005  N  N   . VAL B 1 503 ? 137.146 146.542 147.107 1.00 46.05  ?  492 VAL B N   1 
ATOM   9006  C  CA  . VAL B 1 503 ? 138.148 146.284 146.080 1.00 46.05  ?  492 VAL B CA  1 
ATOM   9007  C  C   . VAL B 1 503 ? 138.148 144.810 145.701 1.00 46.05  ?  492 VAL B C   1 
ATOM   9008  O  O   . VAL B 1 503 ? 138.241 144.458 144.518 1.00 46.05  ?  492 VAL B O   1 
ATOM   9009  C  CB  . VAL B 1 503 ? 139.533 146.755 146.555 1.00 46.05  ?  492 VAL B CB  1 
ATOM   9010  C  CG1 . VAL B 1 503 ? 140.588 146.385 145.549 1.00 46.05  ?  492 VAL B CG1 1 
ATOM   9011  C  CG2 . VAL B 1 503 ? 139.529 148.243 146.773 1.00 46.05  ?  492 VAL B CG2 1 
ATOM   9012  N  N   . ALA B 1 504 ? 138.011 143.926 146.690 1.00 44.98  ?  493 ALA B N   1 
ATOM   9013  C  CA  . ALA B 1 504 ? 137.926 142.501 146.386 1.00 44.98  ?  493 ALA B CA  1 
ATOM   9014  C  C   . ALA B 1 504 ? 136.701 142.181 145.534 1.00 44.98  ?  493 ALA B C   1 
ATOM   9015  O  O   . ALA B 1 504 ? 136.792 141.429 144.555 1.00 44.98  ?  493 ALA B O   1 
ATOM   9016  C  CB  . ALA B 1 504 ? 137.907 141.690 147.678 1.00 44.98  ?  493 ALA B CB  1 
ATOM   9017  N  N   . PHE B 1 505 ? 135.545 142.743 145.885 1.00 44.77  ?  494 PHE B N   1 
ATOM   9018  C  CA  . PHE B 1 505 ? 134.345 142.468 145.106 1.00 44.77  ?  494 PHE B CA  1 
ATOM   9019  C  C   . PHE B 1 505 ? 134.437 143.045 143.700 1.00 44.77  ?  494 PHE B C   1 
ATOM   9020  O  O   . PHE B 1 505 ? 133.930 142.446 142.744 1.00 44.77  ?  494 PHE B O   1 
ATOM   9021  C  CB  . PHE B 1 505 ? 133.115 143.015 145.816 1.00 44.77  ?  494 PHE B CB  1 
ATOM   9022  C  CG  . PHE B 1 505 ? 131.843 142.722 145.101 1.00 44.77  ?  494 PHE B CG  1 
ATOM   9023  C  CD1 . PHE B 1 505 ? 131.261 143.666 144.283 1.00 44.77  ?  494 PHE B CD1 1 
ATOM   9024  C  CD2 . PHE B 1 505 ? 131.244 141.489 145.221 1.00 44.77  ?  494 PHE B CD2 1 
ATOM   9025  C  CE1 . PHE B 1 505 ? 130.106 143.386 143.614 1.00 44.77  ?  494 PHE B CE1 1 
ATOM   9026  C  CE2 . PHE B 1 505 ? 130.087 141.210 144.555 1.00 44.77  ?  494 PHE B CE2 1 
ATOM   9027  C  CZ  . PHE B 1 505 ? 129.517 142.157 143.753 1.00 44.77  ?  494 PHE B CZ  1 
ATOM   9028  N  N   . GLN B 1 506 ? 135.070 144.201 143.553 1.00 45.55  ?  495 GLN B N   1 
ATOM   9029  C  CA  . GLN B 1 506 ? 135.223 144.789 142.234 1.00 45.55  ?  495 GLN B CA  1 
ATOM   9030  C  C   . GLN B 1 506 ? 136.155 143.955 141.367 1.00 45.55  ?  495 GLN B C   1 
ATOM   9031  O  O   . GLN B 1 506 ? 135.965 143.869 140.151 1.00 45.55  ?  495 GLN B O   1 
ATOM   9032  C  CB  . GLN B 1 506 ? 135.715 146.222 142.382 1.00 45.55  ?  495 GLN B CB  1 
ATOM   9033  C  CG  . GLN B 1 506 ? 136.440 146.781 141.211 1.00 45.55  ?  495 GLN B CG  1 
ATOM   9034  C  CD  . GLN B 1 506 ? 137.509 147.734 141.640 1.00 45.55  ?  495 GLN B CD  1 
ATOM   9035  O  OE1 . GLN B 1 506 ? 138.520 147.333 142.197 1.00 45.55  ?  495 GLN B OE1 1 
ATOM   9036  N  NE2 . GLN B 1 506 ? 137.291 149.006 141.396 1.00 45.55  ?  495 GLN B NE2 1 
ATOM   9037  N  N   . LEU B 1 507 ? 137.154 143.313 141.975 1.00 45.62  ?  496 LEU B N   1 
ATOM   9038  C  CA  . LEU B 1 507 ? 137.954 142.346 141.228 1.00 45.62  ?  496 LEU B CA  1 
ATOM   9039  C  C   . LEU B 1 507 ? 137.131 141.127 140.839 1.00 45.62  ?  496 LEU B C   1 
ATOM   9040  O  O   . LEU B 1 507 ? 137.322 140.563 139.760 1.00 45.62  ?  496 LEU B O   1 
ATOM   9041  C  CB  . LEU B 1 507 ? 139.167 141.909 142.040 1.00 45.62  ?  496 LEU B CB  1 
ATOM   9042  C  CG  . LEU B 1 507 ? 140.215 142.952 142.389 1.00 45.62  ?  496 LEU B CG  1 
ATOM   9043  C  CD1 . LEU B 1 507 ? 141.367 142.278 143.082 1.00 45.62  ?  496 LEU B CD1 1 
ATOM   9044  C  CD2 . LEU B 1 507 ? 140.676 143.689 141.159 1.00 45.62  ?  496 LEU B CD2 1 
ATOM   9045  N  N   . LEU B 1 508 ? 136.228 140.693 141.714 1.00 44.58  ?  497 LEU B N   1 
ATOM   9046  C  CA  . LEU B 1 508 ? 135.385 139.545 141.396 1.00 44.58  ?  497 LEU B CA  1 
ATOM   9047  C  C   . LEU B 1 508 ? 134.423 139.839 140.247 1.00 44.58  ?  497 LEU B C   1 
ATOM   9048  O  O   . LEU B 1 508 ? 134.042 138.927 139.506 1.00 44.58  ?  497 LEU B O   1 
ATOM   9049  C  CB  . LEU B 1 508 ? 134.620 139.119 142.646 1.00 44.58  ?  497 LEU B CB  1 
ATOM   9050  C  CG  . LEU B 1 508 ? 133.737 137.880 142.602 1.00 44.58  ?  497 LEU B CG  1 
ATOM   9051  C  CD1 . LEU B 1 508 ? 134.562 136.638 142.372 1.00 44.58  ?  497 LEU B CD1 1 
ATOM   9052  C  CD2 . LEU B 1 508 ? 132.970 137.773 143.890 1.00 44.58  ?  497 LEU B CD2 1 
ATOM   9053  N  N   . THR B 1 509 ? 134.003 141.092 140.092 1.00 44.73  ?  498 THR B N   1 
ATOM   9054  C  CA  . THR B 1 509 ? 133.114 141.426 138.980 1.00 44.73  ?  498 THR B CA  1 
ATOM   9055  C  C   . THR B 1 509 ? 133.787 141.262 137.623 1.00 44.73  ?  498 THR B C   1 
ATOM   9056  O  O   . THR B 1 509 ? 133.095 141.048 136.624 1.00 44.73  ?  498 THR B O   1 
ATOM   9057  C  CB  . THR B 1 509 ? 132.591 142.851 139.108 1.00 44.73  ?  498 THR B CB  1 
ATOM   9058  O  OG1 . THR B 1 509 ? 133.695 143.756 139.194 1.00 44.73  ?  498 THR B OG1 1 
ATOM   9059  C  CG2 . THR B 1 509 ? 131.718 142.988 140.323 1.00 44.73  ?  498 THR B CG2 1 
ATOM   9060  N  N   . ILE B 1 510 ? 135.114 141.377 137.556 1.00 44.79  ?  499 ILE B N   1 
ATOM   9061  C  CA  . ILE B 1 510 ? 135.817 141.117 136.305 1.00 44.79  ?  499 ILE B CA  1 
ATOM   9062  C  C   . ILE B 1 510 ? 135.629 139.668 135.890 1.00 44.79  ?  499 ILE B C   1 
ATOM   9063  O  O   . ILE B 1 510 ? 135.467 139.359 134.707 1.00 44.79  ?  499 ILE B O   1 
ATOM   9064  C  CB  . ILE B 1 510 ? 137.308 141.473 136.437 1.00 44.79  ?  499 ILE B CB  1 
ATOM   9065  C  CG1 . ILE B 1 510 ? 137.490 142.957 136.743 1.00 44.79  ?  499 ILE B CG1 1 
ATOM   9066  C  CG2 . ILE B 1 510 ? 138.050 141.117 135.172 1.00 44.79  ?  499 ILE B CG2 1 
ATOM   9067  C  CD1 . ILE B 1 510 ? 137.027 143.861 135.639 1.00 44.79  ?  499 ILE B CD1 1 
ATOM   9068  N  N   . VAL B 1 511 ? 135.647 138.756 136.858 1.00 43.60  ?  500 VAL B N   1 
ATOM   9069  C  CA  . VAL B 1 511 ? 135.354 137.360 136.569 1.00 43.60  ?  500 VAL B CA  1 
ATOM   9070  C  C   . VAL B 1 511 ? 133.885 137.191 136.216 1.00 43.60  ?  500 VAL B C   1 
ATOM   9071  O  O   . VAL B 1 511 ? 133.540 136.433 135.308 1.00 43.60  ?  500 VAL B O   1 
ATOM   9072  C  CB  . VAL B 1 511 ? 135.763 136.474 137.758 1.00 43.60  ?  500 VAL B CB  1 
ATOM   9073  C  CG1 . VAL B 1 511 ? 135.346 135.048 137.521 1.00 43.60  ?  500 VAL B CG1 1 
ATOM   9074  C  CG2 . VAL B 1 511 ? 137.243 136.551 137.966 1.00 43.60  ?  500 VAL B CG2 1 
ATOM   9075  N  N   . PHE B 1 512 ? 133.001 137.899 136.919 1.00 43.63  ?  501 PHE B N   1 
ATOM   9076  C  CA  . PHE B 1 512 ? 131.580 137.853 136.577 1.00 43.63  ?  501 PHE B CA  1 
ATOM   9077  C  C   . PHE B 1 512 ? 131.344 138.215 135.117 1.00 43.63  ?  501 PHE B C   1 
ATOM   9078  O  O   . PHE B 1 512 ? 130.465 137.646 134.466 1.00 43.63  ?  501 PHE B O   1 
ATOM   9079  C  CB  . PHE B 1 512 ? 130.775 138.796 137.467 1.00 43.63  ?  501 PHE B CB  1 
ATOM   9080  C  CG  . PHE B 1 512 ? 130.608 138.323 138.868 1.00 43.63  ?  501 PHE B CG  1 
ATOM   9081  C  CD1 . PHE B 1 512 ? 130.962 137.046 139.232 1.00 43.63  ?  501 PHE B CD1 1 
ATOM   9082  C  CD2 . PHE B 1 512 ? 130.096 139.168 139.829 1.00 43.63  ?  501 PHE B CD2 1 
ATOM   9083  C  CE1 . PHE B 1 512 ? 130.812 136.623 140.521 1.00 43.63  ?  501 PHE B CE1 1 
ATOM   9084  C  CE2 . PHE B 1 512 ? 129.946 138.748 141.117 1.00 43.63  ?  501 PHE B CE2 1 
ATOM   9085  C  CZ  . PHE B 1 512 ? 130.302 137.475 141.464 1.00 43.63  ?  501 PHE B CZ  1 
ATOM   9086  N  N   . ARG B 1 513 ? 132.115 139.167 134.591 1.00 45.64  ?  502 ARG B N   1 
ATOM   9087  C  CA  . ARG B 1 513 ? 131.931 139.614 133.213 1.00 45.64  ?  502 ARG B CA  1 
ATOM   9088  C  C   . ARG B 1 513 ? 132.310 138.534 132.211 1.00 45.64  ?  502 ARG B C   1 
ATOM   9089  O  O   . ARG B 1 513 ? 131.681 138.406 131.157 1.00 45.64  ?  502 ARG B O   1 
ATOM   9090  C  CB  . ARG B 1 513 ? 132.765 140.861 132.951 1.00 45.64  ?  502 ARG B CB  1 
ATOM   9091  C  CG  . ARG B 1 513 ? 132.227 142.113 133.543 1.00 45.64  ?  502 ARG B CG  1 
ATOM   9092  C  CD  . ARG B 1 513 ? 133.156 143.245 133.240 1.00 45.64  ?  502 ARG B CD  1 
ATOM   9093  N  NE  . ARG B 1 513 ? 132.781 144.460 133.944 1.00 45.64  ?  502 ARG B NE  1 
ATOM   9094  C  CZ  . ARG B 1 513 ? 131.957 145.376 133.457 1.00 45.64  ?  502 ARG B CZ  1 
ATOM   9095  N  NH1 . ARG B 1 513 ? 131.675 146.451 134.169 1.00 45.64  1  502 ARG B NH1 1 
ATOM   9096  N  NH2 . ARG B 1 513 ? 131.417 145.214 132.262 1.00 45.64  ?  502 ARG B NH2 1 
ATOM   9097  N  N   . THR B 1 514 ? 133.357 137.769 132.502 1.00 43.88  ?  503 THR B N   1 
ATOM   9098  C  CA  . THR B 1 514 ? 133.943 136.847 131.545 1.00 43.88  ?  503 THR B CA  1 
ATOM   9099  C  C   . THR B 1 514 ? 133.645 135.395 131.866 1.00 43.88  ?  503 THR B C   1 
ATOM   9100  O  O   . THR B 1 514 ? 134.221 134.505 131.246 1.00 43.88  ?  503 THR B O   1 
ATOM   9101  C  CB  . THR B 1 514 ? 135.452 137.065 131.479 1.00 43.88  ?  503 THR B CB  1 
ATOM   9102  O  OG1 . THR B 1 514 ? 136.007 136.931 132.787 1.00 43.88  ?  503 THR B OG1 1 
ATOM   9103  C  CG2 . THR B 1 514 ? 135.755 138.439 130.971 1.00 43.88  ?  503 THR B CG2 1 
ATOM   9104  N  N   . GLN B 1 515 ? 132.742 135.146 132.800 1.00 44.62  ?  504 GLN B N   1 
ATOM   9105  C  CA  . GLN B 1 515 ? 132.450 133.844 133.381 1.00 44.62  ?  504 GLN B CA  1 
ATOM   9106  C  C   . GLN B 1 515 ? 131.634 132.961 132.448 1.00 44.62  ?  504 GLN B C   1 
ATOM   9107  O  O   . GLN B 1 515 ? 131.933 131.777 132.287 1.00 44.62  ?  504 GLN B O   1 
ATOM   9108  C  CB  . GLN B 1 515 ? 131.695 134.073 134.683 1.00 44.62  ?  504 GLN B CB  1 
ATOM   9109  C  CG  . GLN B 1 515 ? 131.687 132.985 135.675 1.00 44.62  ?  504 GLN B CG  1 
ATOM   9110  C  CD  . GLN B 1 515 ? 130.838 133.379 136.841 1.00 44.62  ?  504 GLN B CD  1 
ATOM   9111  O  OE1 . GLN B 1 515 ? 130.120 134.361 136.772 1.00 44.62  ?  504 GLN B OE1 1 
ATOM   9112  N  NE2 . GLN B 1 515 ? 130.904 132.623 137.915 1.00 44.62  ?  504 GLN B NE2 1 
ATOM   9113  N  N   . PHE B 1 516 ? 130.589 133.522 131.841 1.00 43.07  ?  505 PHE B N   1 
ATOM   9114  C  CA  . PHE B 1 516 ? 129.698 132.811 130.933 1.00 43.07  ?  505 PHE B CA  1 
ATOM   9115  C  C   . PHE B 1 516 ? 129.691 133.550 129.603 1.00 43.07  ?  505 PHE B C   1 
ATOM   9116  O  O   . PHE B 1 516 ? 128.708 134.223 129.267 1.00 43.07  ?  505 PHE B O   1 
ATOM   9117  C  CB  . PHE B 1 516 ? 128.282 132.716 131.496 1.00 43.07  ?  505 PHE B CB  1 
ATOM   9118  C  CG  . PHE B 1 516 ? 128.211 132.139 132.874 1.00 43.07  ?  505 PHE B CG  1 
ATOM   9119  C  CD1 . PHE B 1 516 ? 128.880 130.976 133.188 1.00 43.07  ?  505 PHE B CD1 1 
ATOM   9120  C  CD2 . PHE B 1 516 ? 127.470 132.760 133.855 1.00 43.07  ?  505 PHE B CD2 1 
ATOM   9121  C  CE1 . PHE B 1 516 ? 128.813 130.447 134.452 1.00 43.07  ?  505 PHE B CE1 1 
ATOM   9122  C  CE2 . PHE B 1 516 ? 127.399 132.230 135.119 1.00 43.07  ?  505 PHE B CE2 1 
ATOM   9123  C  CZ  . PHE B 1 516 ? 128.072 131.073 135.417 1.00 43.07  ?  505 PHE B CZ  1 
ATOM   9124  N  N   . PRO B 1 517 ? 130.761 133.443 128.819 1.00 45.64  ?  506 PRO B N   1 
ATOM   9125  C  CA  . PRO B 1 517 ? 130.828 134.191 127.560 1.00 45.64  ?  506 PRO B CA  1 
ATOM   9126  C  C   . PRO B 1 517 ? 129.716 133.791 126.606 1.00 45.64  ?  506 PRO B C   1 
ATOM   9127  O  O   . PRO B 1 517 ? 129.326 132.628 126.529 1.00 45.64  ?  506 PRO B O   1 
ATOM   9128  C  CB  . PRO B 1 517 ? 132.202 133.814 127.000 1.00 45.64  ?  506 PRO B CB  1 
ATOM   9129  C  CG  . PRO B 1 517 ? 132.930 133.217 128.118 1.00 45.64  ?  506 PRO B CG  1 
ATOM   9130  C  CD  . PRO B 1 517 ? 131.941 132.595 129.009 1.00 45.64  ?  506 PRO B CD  1 
ATOM   9131  N  N   . LYS B 1 518 ? 129.231 134.755 125.841 1.00 49.07  ?  507 LYS B N   1 
ATOM   9132  C  CA  . LYS B 1 518 ? 128.213 134.457 124.852 1.00 49.07  ?  507 LYS B CA  1 
ATOM   9133  C  C   . LYS B 1 518 ? 128.876 133.896 123.614 1.00 49.07  ?  507 LYS B C   1 
ATOM   9134  O  O   . LYS B 1 518 ? 129.101 134.611 122.648 1.00 49.07  ?  507 LYS B O   1 
ATOM   9135  C  CB  . LYS B 1 518 ? 127.407 135.708 124.527 1.00 49.07  ?  507 LYS B CB  1 
ATOM   9136  C  CG  . LYS B 1 518 ? 126.671 136.284 125.723 1.00 49.07  ?  507 LYS B CG  1 
ATOM   9137  C  CD  . LYS B 1 518 ? 127.120 137.705 126.017 1.00 49.07  ?  507 LYS B CD  1 
ATOM   9138  C  CE  . LYS B 1 518 ? 126.504 138.220 127.308 1.00 49.07  ?  507 LYS B CE  1 
ATOM   9139  N  NZ  . LYS B 1 518 ? 126.911 137.395 128.479 1.00 49.07  1  507 LYS B NZ  1 
ATOM   9140  N  N   . CYS B 1 519 ? 129.200 132.613 123.646 1.00 47.61  ?  508 CYS B N   1 
ATOM   9141  C  CA  . CYS B 1 519 ? 129.861 131.968 122.523 1.00 47.61  ?  508 CYS B CA  1 
ATOM   9142  C  C   . CYS B 1 519 ? 128.902 131.779 121.369 1.00 47.61  ?  508 CYS B C   1 
ATOM   9143  O  O   . CYS B 1 519 ? 127.692 131.744 121.565 1.00 47.61  ?  508 CYS B O   1 
ATOM   9144  C  CB  . CYS B 1 519 ? 130.439 130.632 122.968 1.00 47.61  ?  508 CYS B CB  1 
ATOM   9145  S  SG  . CYS B 1 519 ? 131.645 130.747 124.304 1.00 47.61  ?  508 CYS B SG  1 
ATOM   9146  N  N   . SER B 1 520 ? 129.427 131.654 120.160 1.00 43.21  ?  509 SER B N   1 
ATOM   9147  C  CA  . SER B 1 520 ? 128.548 131.584 119.004 1.00 43.21  ?  509 SER B CA  1 
ATOM   9148  C  C   . SER B 1 520 ? 129.082 130.767 117.861 1.00 43.21  ?  509 SER B C   1 
ATOM   9149  O  O   . SER B 1 520 ? 130.269 130.486 117.799 1.00 43.21  ?  509 SER B O   1 
ATOM   9150  C  CB  . SER B 1 520 ? 128.270 133.001 118.497 1.00 43.21  ?  509 SER B CB  1 
ATOM   9151  O  OG  . SER B 1 520 ? 129.473 133.676 118.181 1.00 43.21  ?  509 SER B OG  1 
ATOM   9152  N  N   . THR B 1 521 ? 128.200 130.385 116.954 1.00 42.73  ?  510 THR B N   1 
ATOM   9153  C  CA  . THR B 1 521 ? 128.611 129.669 115.772 1.00 42.73  ?  510 THR B CA  1 
ATOM   9154  C  C   . THR B 1 521 ? 128.534 130.678 114.660 1.00 42.73  ?  510 THR B C   1 
ATOM   9155  O  O   . THR B 1 521 ? 127.591 131.452 114.596 1.00 42.73  ?  510 THR B O   1 
ATOM   9156  C  CB  . THR B 1 521 ? 127.686 128.485 115.465 1.00 42.73  ?  510 THR B CB  1 
ATOM   9157  O  OG1 . THR B 1 521 ? 127.706 127.568 116.564 1.00 42.73  ?  510 THR B OG1 1 
ATOM   9158  C  CG2 . THR B 1 521 ? 128.138 127.765 114.207 1.00 42.73  ?  510 THR B CG2 1 
ATOM   9159  N  N   . LEU B 1 522 ? 129.528 130.698 113.789 1.00 41.44  ?  511 LEU B N   1 
ATOM   9160  C  CA  . LEU B 1 522 ? 129.552 131.706 112.744 1.00 41.44  ?  511 LEU B CA  1 
ATOM   9161  C  C   . LEU B 1 522 ? 129.225 131.135 111.388 1.00 41.44  ?  511 LEU B C   1 
ATOM   9162  O  O   . LEU B 1 522 ? 129.452 129.960 111.130 1.00 41.44  ?  511 LEU B O   1 
ATOM   9163  C  CB  . LEU B 1 522 ? 130.910 132.413 112.705 1.00 41.44  ?  511 LEU B CB  1 
ATOM   9164  C  CG  . LEU B 1 522 ? 131.403 133.014 114.019 1.00 41.44  ?  511 LEU B CG  1 
ATOM   9165  C  CD1 . LEU B 1 522 ? 132.750 133.685 113.815 1.00 41.44  ?  511 LEU B CD1 1 
ATOM   9166  C  CD2 . LEU B 1 522 ? 130.390 133.996 114.581 1.00 41.44  ?  511 LEU B CD2 1 
ATOM   9167  N  N   . ALA B 1 523 ? 128.641 131.948 110.525 1.00 43.80  ?  512 ALA B N   1 
ATOM   9168  C  CA  . ALA B 1 523 ? 128.337 131.506 109.176 1.00 43.80  ?  512 ALA B CA  1 
ATOM   9169  C  C   . ALA B 1 523 ? 128.719 132.590 108.195 1.00 43.80  ?  512 ALA B C   1 
ATOM   9170  O  O   . ALA B 1 523 ? 128.934 133.726 108.589 1.00 43.80  ?  512 ALA B O   1 
ATOM   9171  C  CB  . ALA B 1 523 ? 126.869 131.153 109.044 1.00 43.80  ?  512 ALA B CB  1 
ATOM   9172  N  N   . ASN B 1 524 ? 128.802 132.250 106.920 1.00 45.32  ?  513 ASN B N   1 
ATOM   9173  C  CA  . ASN B 1 524 ? 129.210 133.210 105.908 1.00 45.32  ?  513 ASN B CA  1 
ATOM   9174  C  C   . ASN B 1 524 ? 128.056 134.039 105.399 1.00 45.32  ?  513 ASN B C   1 
ATOM   9175  O  O   . ASN B 1 524 ? 126.999 133.505 105.095 1.00 45.32  ?  513 ASN B O   1 
ATOM   9176  C  CB  . ASN B 1 524 ? 129.857 132.472 104.738 1.00 45.32  ?  513 ASN B CB  1 
ATOM   9177  C  CG  . ASN B 1 524 ? 130.648 133.386 103.830 1.00 45.32  ?  513 ASN B CG  1 
ATOM   9178  O  OD1 . ASN B 1 524 ? 131.344 134.288 104.287 1.00 45.32  ?  513 ASN B OD1 1 
ATOM   9179  N  ND2 . ASN B 1 524 ? 130.563 133.139 102.534 1.00 45.32  ?  513 ASN B ND2 1 
ATOM   9180  N  N   . ILE B 1 525 ? 128.246 135.348 105.316 1.00 48.64  ?  514 ILE B N   1 
ATOM   9181  C  CA  . ILE B 1 525 ? 127.228 136.214 104.759 1.00 48.64  ?  514 ILE B CA  1 
ATOM   9182  C  C   . ILE B 1 525 ? 127.794 136.875 103.523 1.00 48.64  ?  514 ILE B C   1 
ATOM   9183  O  O   . ILE B 1 525 ? 128.886 137.433 103.569 1.00 48.64  ?  514 ILE B O   1 
ATOM   9184  C  CB  . ILE B 1 525 ? 126.818 137.326 105.727 1.00 48.64  ?  514 ILE B CB  1 
ATOM   9185  C  CG1 . ILE B 1 525 ? 127.000 136.883 107.175 1.00 48.64  ?  514 ILE B CG1 1 
ATOM   9186  C  CG2 . ILE B 1 525 ? 125.380 137.757 105.470 1.00 48.64  ?  514 ILE B CG2 1 
ATOM   9187  C  CD1 . ILE B 1 525 ? 126.562 137.938 108.160 1.00 48.64  ?  514 ILE B CD1 1 
ATOM   9188  N  N   . GLY B 1 526 ? 127.076 136.806 102.411 1.00 50.13  ?  515 GLY B N   1 
ATOM   9189  C  CA  . GLY B 1 526 ? 127.515 137.468 101.199 1.00 50.13  ?  515 GLY B CA  1 
ATOM   9190  C  C   . GLY B 1 526 ? 128.440 136.677 100.312 1.00 50.13  ?  515 GLY B C   1 
ATOM   9191  O  O   . GLY B 1 526 ? 128.886 137.183 99.290  1.00 50.13  ?  515 GLY B O   1 
ATOM   9192  N  N   . ARG B 1 527 ? 128.730 135.442 100.686 1.00 52.42  ?  516 ARG B N   1 
ATOM   9193  C  CA  . ARG B 1 527 ? 129.661 134.618 99.915  1.00 52.42  ?  516 ARG B CA  1 
ATOM   9194  C  C   . ARG B 1 527 ? 131.012 135.292 99.724  1.00 52.42  ?  516 ARG B C   1 
ATOM   9195  O  O   . ARG B 1 527 ? 131.567 135.265 98.633  1.00 52.42  ?  516 ARG B O   1 
ATOM   9196  C  CB  . ARG B 1 527 ? 129.053 134.227 98.568  1.00 52.42  ?  516 ARG B CB  1 
ATOM   9197  C  CG  . ARG B 1 527 ? 127.937 133.205 98.686  1.00 52.42  ?  516 ARG B CG  1 
ATOM   9198  C  CD  . ARG B 1 527 ? 128.301 132.123 99.690  1.00 52.42  ?  516 ARG B CD  1 
ATOM   9199  N  NE  . ARG B 1 527 ? 127.328 131.035 99.697  1.00 52.42  ?  516 ARG B NE  1 
ATOM   9200  C  CZ  . ARG B 1 527 ? 127.473 129.904 99.016  1.00 52.42  ?  516 ARG B CZ  1 
ATOM   9201  N  NH1 . ARG B 1 527 ? 128.557 129.706 98.281  1.00 52.42  1  516 ARG B NH1 1 
ATOM   9202  N  NH2 . ARG B 1 527 ? 126.537 128.967 99.075  1.00 52.42  ?  516 ARG B NH2 1 
ATOM   9203  N  N   . THR B 1 528 ? 131.543 135.891 100.783 1.00 45.31  ?  517 THR B N   1 
ATOM   9204  C  CA  . THR B 1 528 ? 132.844 136.538 100.722 1.00 45.31  ?  517 THR B CA  1 
ATOM   9205  C  C   . THR B 1 528 ? 133.361 136.375 102.133 1.00 45.31  ?  517 THR B C   1 
ATOM   9206  O  O   . THR B 1 528 ? 132.761 135.664 102.928 1.00 45.31  ?  517 THR B O   1 
ATOM   9207  C  CB  . THR B 1 528 ? 132.710 138.066 100.706 1.00 45.31  ?  517 THR B CB  1 
ATOM   9208  O  OG1 . THR B 1 528 ? 131.820 138.479 101.750 1.00 45.31  ?  517 THR B OG1 1 
ATOM   9209  C  CG2 . THR B 1 528 ? 132.158 138.537 99.373  1.00 45.31  ?  517 THR B CG2 1 
ATOM   9210  N  N   . ASN B 1 529 ? 134.460 137.042 102.458 1.00 38.38  ?  518 ASN B N   1 
ATOM   9211  C  CA  . ASN B 1 529 ? 135.242 136.743 103.647 1.00 38.38  ?  518 ASN B CA  1 
ATOM   9212  C  C   . ASN B 1 529 ? 134.614 137.271 104.932 1.00 38.38  ?  518 ASN B C   1 
ATOM   9213  O  O   . ASN B 1 529 ? 135.331 137.482 105.911 1.00 38.38  ?  518 ASN B O   1 
ATOM   9214  C  CB  . ASN B 1 529 ? 136.657 137.290 103.480 1.00 38.38  ?  518 ASN B CB  1 
ATOM   9215  C  CG  . ASN B 1 529 ? 136.686 138.762 103.197 1.00 38.38  ?  518 ASN B CG  1 
ATOM   9216  O  OD1 . ASN B 1 529 ? 135.693 139.346 102.798 1.00 38.38  ?  518 ASN B OD1 1 
ATOM   9217  N  ND2 . ASN B 1 529 ? 137.831 139.374 103.404 1.00 38.38  ?  518 ASN B ND2 1 
ATOM   9218  N  N   . ILE B 1 530 ? 133.300 137.469 104.976 1.00 39.00  ?  519 ILE B N   1 
ATOM   9219  C  CA  . ILE B 1 530 ? 132.622 138.005 106.153 1.00 39.00  ?  519 ILE B CA  1 
ATOM   9220  C  C   . ILE B 1 530 ? 131.861 136.877 106.835 1.00 39.00  ?  519 ILE B C   1 
ATOM   9221  O  O   . ILE B 1 530 ? 131.039 136.203 106.208 1.00 39.00  ?  519 ILE B O   1 
ATOM   9222  C  CB  . ILE B 1 530 ? 131.677 139.159 105.790 1.00 39.00  ?  519 ILE B CB  1 
ATOM   9223  C  CG1 . ILE B 1 530 ? 132.456 140.316 105.182 1.00 39.00  ?  519 ILE B CG1 1 
ATOM   9224  C  CG2 . ILE B 1 530 ? 130.920 139.629 107.007 1.00 39.00  ?  519 ILE B CG2 1 
ATOM   9225  C  CD1 . ILE B 1 530 ? 131.603 141.274 104.443 1.00 39.00  ?  519 ILE B CD1 1 
ATOM   9226  N  N   . TYR B 1 531 ? 132.126 136.681 108.123 1.00 38.96  ?  520 TYR B N   1 
ATOM   9227  C  CA  . TYR B 1 531 ? 131.497 135.629 108.914 1.00 38.96  ?  520 TYR B CA  1 
ATOM   9228  C  C   . TYR B 1 531 ? 130.901 136.262 110.158 1.00 38.96  ?  520 TYR B C   1 
ATOM   9229  O  O   . TYR B 1 531 ? 131.592 136.976 110.884 1.00 38.96  ?  520 TYR B O   1 
ATOM   9230  C  CB  . TYR B 1 531 ? 132.500 134.539 109.285 1.00 38.96  ?  520 TYR B CB  1 
ATOM   9231  C  CG  . TYR B 1 531 ? 133.045 133.819 108.089 1.00 38.96  ?  520 TYR B CG  1 
ATOM   9232  C  CD1 . TYR B 1 531 ? 134.079 134.358 107.349 1.00 38.96  ?  520 TYR B CD1 1 
ATOM   9233  C  CD2 . TYR B 1 531 ? 132.520 132.613 107.691 1.00 38.96  ?  520 TYR B CD2 1 
ATOM   9234  C  CE1 . TYR B 1 531 ? 134.566 133.723 106.258 1.00 38.96  ?  520 TYR B CE1 1 
ATOM   9235  C  CE2 . TYR B 1 531 ? 133.007 131.968 106.599 1.00 38.96  ?  520 TYR B CE2 1 
ATOM   9236  C  CZ  . TYR B 1 531 ? 134.029 132.530 105.885 1.00 38.96  ?  520 TYR B CZ  1 
ATOM   9237  O  OH  . TYR B 1 531 ? 134.526 131.888 104.792 1.00 38.96  ?  520 TYR B OH  1 
ATOM   9238  N  N   . LYS B 1 532 ? 129.629 136.005 110.405 1.00 44.85  ?  521 LYS B N   1 
ATOM   9239  C  CA  . LYS B 1 532 ? 128.932 136.604 111.533 1.00 44.85  ?  521 LYS B CA  1 
ATOM   9240  C  C   . LYS B 1 532 ? 128.093 135.556 112.240 1.00 44.85  ?  521 LYS B C   1 
ATOM   9241  O  O   . LYS B 1 532 ? 128.014 134.412 111.818 1.00 44.85  ?  521 LYS B O   1 
ATOM   9242  C  CB  . LYS B 1 532 ? 128.068 137.780 111.081 1.00 44.85  ?  521 LYS B CB  1 
ATOM   9243  C  CG  . LYS B 1 532 ? 128.855 138.903 110.459 1.00 44.85  ?  521 LYS B CG  1 
ATOM   9244  C  CD  . LYS B 1 532 ? 128.378 140.237 110.923 1.00 44.85  ?  521 LYS B CD  1 
ATOM   9245  C  CE  . LYS B 1 532 ? 129.453 141.275 110.767 1.00 44.85  ?  521 LYS B CE  1 
ATOM   9246  N  NZ  . LYS B 1 532 ? 130.687 140.881 111.494 1.00 44.85  1  521 LYS B NZ  1 
ATOM   9247  N  N   . ASN B 1 533 ? 127.456 135.968 113.327 1.00 49.96  ?  522 ASN B N   1 
ATOM   9248  C  CA  . ASN B 1 533 ? 126.658 135.055 114.129 1.00 49.96  ?  522 ASN B CA  1 
ATOM   9249  C  C   . ASN B 1 533 ? 125.589 134.385 113.281 1.00 49.96  ?  522 ASN B C   1 
ATOM   9250  O  O   . ASN B 1 533 ? 124.780 135.048 112.634 1.00 49.96  ?  522 ASN B O   1 
ATOM   9251  C  CB  . ASN B 1 533 ? 126.024 135.808 115.289 1.00 49.96  ?  522 ASN B CB  1 
ATOM   9252  C  CG  . ASN B 1 533 ? 125.487 134.896 116.357 1.00 49.96  ?  522 ASN B CG  1 
ATOM   9253  O  OD1 . ASN B 1 533 ? 125.140 133.753 116.102 1.00 49.96  ?  522 ASN B OD1 1 
ATOM   9254  N  ND2 . ASN B 1 533 ? 125.409 135.405 117.569 1.00 49.96  ?  522 ASN B ND2 1 
ATOM   9255  N  N   . LYS B 1 534 ? 125.595 133.055 113.300 1.00 51.64  ?  523 LYS B N   1 
ATOM   9256  C  CA  . LYS B 1 534 ? 124.717 132.247 112.467 1.00 51.64  ?  523 LYS B CA  1 
ATOM   9257  C  C   . LYS B 1 534 ? 123.242 132.515 112.732 1.00 51.64  ?  523 LYS B C   1 
ATOM   9258  O  O   . LYS B 1 534 ? 122.403 132.208 111.883 1.00 51.64  ?  523 LYS B O   1 
ATOM   9259  C  CB  . LYS B 1 534 ? 125.064 130.783 112.706 1.00 51.64  ?  523 LYS B CB  1 
ATOM   9260  C  CG  . LYS B 1 534 ? 124.249 129.779 111.974 1.00 51.64  ?  523 LYS B CG  1 
ATOM   9261  C  CD  . LYS B 1 534 ? 124.307 128.460 112.698 1.00 51.64  ?  523 LYS B CD  1 
ATOM   9262  C  CE  . LYS B 1 534 ? 123.212 127.534 112.229 1.00 51.64  ?  523 LYS B CE  1 
ATOM   9263  N  NZ  . LYS B 1 534 ? 123.334 126.201 112.865 1.00 51.64  1  523 LYS B NZ  1 
ATOM   9264  N  N   . LYS B 1 535 ? 122.911 133.104 113.874 1.00 60.23  ?  524 LYS B N   1 
ATOM   9265  C  CA  . LYS B 1 535 ? 121.535 133.355 114.262 1.00 60.23  ?  524 LYS B CA  1 
ATOM   9266  C  C   . LYS B 1 535 ? 121.074 134.776 113.982 1.00 60.23  ?  524 LYS B C   1 
ATOM   9267  O  O   . LYS B 1 535 ? 119.925 135.101 114.272 1.00 60.23  ?  524 LYS B O   1 
ATOM   9268  C  CB  . LYS B 1 535 ? 121.356 133.058 115.749 1.00 60.23  ?  524 LYS B CB  1 
ATOM   9269  C  CG  . LYS B 1 535 ? 121.459 131.603 116.095 1.00 60.23  ?  524 LYS B CG  1 
ATOM   9270  C  CD  . LYS B 1 535 ? 120.788 131.316 117.410 1.00 60.23  ?  524 LYS B CD  1 
ATOM   9271  C  CE  . LYS B 1 535 ? 121.626 131.801 118.563 1.00 60.23  ?  524 LYS B CE  1 
ATOM   9272  N  NZ  . LYS B 1 535 ? 121.288 131.064 119.805 1.00 60.23  1  524 LYS B NZ  1 
ATOM   9273  N  N   . ASP B 1 536 ? 121.926 135.623 113.416 1.00 59.90  ?  525 ASP B N   1 
ATOM   9274  C  CA  . ASP B 1 536 ? 121.643 137.048 113.350 1.00 59.90  ?  525 ASP B CA  1 
ATOM   9275  C  C   . ASP B 1 536 ? 121.121 137.515 112.005 1.00 59.90  ?  525 ASP B C   1 
ATOM   9276  O  O   . ASP B 1 536 ? 120.394 138.506 111.957 1.00 59.90  ?  525 ASP B O   1 
ATOM   9277  C  CB  . ASP B 1 536 ? 122.898 137.850 113.696 1.00 59.90  ?  525 ASP B CB  1 
ATOM   9278  C  CG  . ASP B 1 536 ? 123.158 137.910 115.177 1.00 59.90  ?  525 ASP B CG  1 
ATOM   9279  O  OD1 . ASP B 1 536 ? 122.368 137.334 115.943 1.00 59.90  ?  525 ASP B OD1 1 
ATOM   9280  O  OD2 . ASP B 1 536 ? 124.157 138.538 115.581 1.00 59.90  -1 525 ASP B OD2 1 
ATOM   9281  N  N   . TYR B 1 537 ? 121.464 136.846 110.913 1.00 57.33  ?  526 TYR B N   1 
ATOM   9282  C  CA  . TYR B 1 537 ? 121.104 137.319 109.588 1.00 57.33  ?  526 TYR B CA  1 
ATOM   9283  C  C   . TYR B 1 537 ? 120.391 136.222 108.819 1.00 57.33  ?  526 TYR B C   1 
ATOM   9284  O  O   . TYR B 1 537 ? 120.449 135.045 109.172 1.00 57.33  ?  526 TYR B O   1 
ATOM   9285  C  CB  . TYR B 1 537 ? 122.333 137.785 108.798 1.00 57.33  ?  526 TYR B CB  1 
ATOM   9286  C  CG  . TYR B 1 537 ? 123.137 138.844 109.495 1.00 57.33  ?  526 TYR B CG  1 
ATOM   9287  C  CD1 . TYR B 1 537 ? 122.940 140.180 109.218 1.00 57.33  ?  526 TYR B CD1 1 
ATOM   9288  C  CD2 . TYR B 1 537 ? 124.087 138.507 110.438 1.00 57.33  ?  526 TYR B CD2 1 
ATOM   9289  C  CE1 . TYR B 1 537 ? 123.666 141.146 109.859 1.00 57.33  ?  526 TYR B CE1 1 
ATOM   9290  C  CE2 . TYR B 1 537 ? 124.810 139.463 111.084 1.00 57.33  ?  526 TYR B CE2 1 
ATOM   9291  C  CZ  . TYR B 1 537 ? 124.601 140.780 110.789 1.00 57.33  ?  526 TYR B CZ  1 
ATOM   9292  O  OH  . TYR B 1 537 ? 125.332 141.740 111.438 1.00 57.33  ?  526 TYR B OH  1 
ATOM   9293  N  N   . TYR B 1 538 ? 119.714 136.628 107.755 1.00 63.57  ?  527 TYR B N   1 
ATOM   9294  C  CA  . TYR B 1 538 ? 119.085 135.685 106.850 1.00 63.57  ?  527 TYR B CA  1 
ATOM   9295  C  C   . TYR B 1 538 ? 120.037 135.325 105.719 1.00 63.57  ?  527 TYR B C   1 
ATOM   9296  O  O   . TYR B 1 538 ? 120.943 136.083 105.370 1.00 63.57  ?  527 TYR B O   1 
ATOM   9297  C  CB  . TYR B 1 538 ? 117.802 136.266 106.264 1.00 63.57  ?  527 TYR B CB  1 
ATOM   9298  C  CG  . TYR B 1 538 ? 116.669 136.398 107.242 1.00 63.57  ?  527 TYR B CG  1 
ATOM   9299  C  CD1 . TYR B 1 538 ? 115.982 135.283 107.688 1.00 63.57  ?  527 TYR B CD1 1 
ATOM   9300  C  CD2 . TYR B 1 538 ? 116.273 137.640 107.707 1.00 63.57  ?  527 TYR B CD2 1 
ATOM   9301  C  CE1 . TYR B 1 538 ? 114.941 135.399 108.579 1.00 63.57  ?  527 TYR B CE1 1 
ATOM   9302  C  CE2 . TYR B 1 538 ? 115.234 137.766 108.596 1.00 63.57  ?  527 TYR B CE2 1 
ATOM   9303  C  CZ  . TYR B 1 538 ? 114.570 136.642 109.029 1.00 63.57  ?  527 TYR B CZ  1 
ATOM   9304  O  OH  . TYR B 1 538 ? 113.530 136.760 109.919 1.00 63.57  ?  527 TYR B OH  1 
ATOM   9305  N  N   . ASP B 1 539 ? 119.811 134.149 105.140 1.00 63.22  ?  528 ASP B N   1 
ATOM   9306  C  CA  . ASP B 1 539 ? 120.550 133.686 103.968 1.00 63.22  ?  528 ASP B CA  1 
ATOM   9307  C  C   . ASP B 1 539 ? 122.041 133.550 104.250 1.00 63.22  ?  528 ASP B C   1 
ATOM   9308  O  O   . ASP B 1 539 ? 122.876 133.871 103.406 1.00 63.22  ?  528 ASP B O   1 
ATOM   9309  C  CB  . ASP B 1 539 ? 120.308 134.607 102.770 1.00 63.22  ?  528 ASP B CB  1 
ATOM   9310  C  CG  . ASP B 1 539 ? 118.873 134.566 102.292 1.00 63.22  ?  528 ASP B CG  1 
ATOM   9311  O  OD1 . ASP B 1 539 ? 118.608 134.999 101.154 1.00 63.22  ?  528 ASP B OD1 1 
ATOM   9312  O  OD2 . ASP B 1 539 ? 118.007 134.092 103.055 1.00 63.22  -1 528 ASP B OD2 1 
ATOM   9313  N  N   . MET B 1 540 ? 122.391 133.078 105.437 1.00 56.00  ?  529 MET B N   1 
ATOM   9314  C  CA  . MET B 1 540 ? 123.773 132.766 105.749 1.00 56.00  ?  529 MET B CA  1 
ATOM   9315  C  C   . MET B 1 540 ? 124.113 131.375 105.236 1.00 56.00  ?  529 MET B C   1 
ATOM   9316  O  O   . MET B 1 540 ? 123.244 130.613 104.820 1.00 56.00  ?  529 MET B O   1 
ATOM   9317  C  CB  . MET B 1 540 ? 124.014 132.864 107.249 1.00 56.00  ?  529 MET B CB  1 
ATOM   9318  C  CG  . MET B 1 540 ? 123.478 134.138 107.846 1.00 56.00  ?  529 MET B CG  1 
ATOM   9319  S  SD  . MET B 1 540 ? 123.924 134.369 109.562 1.00 56.00  ?  529 MET B SD  1 
ATOM   9320  C  CE  . MET B 1 540 ? 125.636 134.807 109.392 1.00 56.00  ?  529 MET B CE  1 
ATOM   9321  N  N   . TYR B 1 541 ? 125.398 131.050 105.260 1.00 51.83  ?  530 TYR B N   1 
ATOM   9322  C  CA  . TYR B 1 541 ? 125.886 129.829 104.631 1.00 51.83  ?  530 TYR B CA  1 
ATOM   9323  C  C   . TYR B 1 541 ? 126.988 129.230 105.488 1.00 51.83  ?  530 TYR B C   1 
ATOM   9324  O  O   . TYR B 1 541 ? 127.980 129.897 105.780 1.00 51.83  ?  530 TYR B O   1 
ATOM   9325  C  CB  . TYR B 1 541 ? 126.388 130.119 103.221 1.00 51.83  ?  530 TYR B CB  1 
ATOM   9326  C  CG  . TYR B 1 541 ? 127.178 129.003 102.597 1.00 51.83  ?  530 TYR B CG  1 
ATOM   9327  C  CD1 . TYR B 1 541 ? 128.547 129.098 102.449 1.00 51.83  ?  530 TYR B CD1 1 
ATOM   9328  C  CD2 . TYR B 1 541 ? 126.552 127.861 102.143 1.00 51.83  ?  530 TYR B CD2 1 
ATOM   9329  C  CE1 . TYR B 1 541 ? 129.268 128.087 101.878 1.00 51.83  ?  530 TYR B CE1 1 
ATOM   9330  C  CE2 . TYR B 1 541 ? 127.266 126.843 101.571 1.00 51.83  ?  530 TYR B CE2 1 
ATOM   9331  C  CZ  . TYR B 1 541 ? 128.622 126.961 101.439 1.00 51.83  ?  530 TYR B CZ  1 
ATOM   9332  O  OH  . TYR B 1 541 ? 129.337 125.941 100.864 1.00 51.83  ?  530 TYR B OH  1 
ATOM   9333  N  N   . GLU B 1 542 ? 126.811 127.980 105.898 1.00 52.57  ?  531 GLU B N   1 
ATOM   9334  C  CA  . GLU B 1 542 ? 127.892 127.213 106.488 1.00 52.57  ?  531 GLU B CA  1 
ATOM   9335  C  C   . GLU B 1 542 ? 128.384 126.207 105.469 1.00 52.57  ?  531 GLU B C   1 
ATOM   9336  O  O   . GLU B 1 542 ? 127.573 125.417 104.971 1.00 52.57  ?  531 GLU B O   1 
ATOM   9337  C  CB  . GLU B 1 542 ? 127.433 126.487 107.742 1.00 52.57  ?  531 GLU B CB  1 
ATOM   9338  C  CG  . GLU B 1 542 ? 126.725 127.326 108.768 1.00 52.57  ?  531 GLU B CG  1 
ATOM   9339  C  CD  . GLU B 1 542 ? 126.590 126.598 110.086 1.00 52.57  ?  531 GLU B CD  1 
ATOM   9340  O  OE1 . GLU B 1 542 ? 127.622 126.274 110.703 1.00 52.57  ?  531 GLU B OE1 1 
ATOM   9341  O  OE2 . GLU B 1 542 ? 125.450 126.328 110.500 1.00 52.57  -1 531 GLU B OE2 1 
ATOM   9342  N  N   . PRO B 1 543 ? 129.666 126.189 105.121 1.00 51.66  ?  532 PRO B N   1 
ATOM   9343  C  CA  . PRO B 1 543 ? 130.166 125.118 104.260 1.00 51.66  ?  532 PRO B CA  1 
ATOM   9344  C  C   . PRO B 1 543 ? 129.950 123.773 104.927 1.00 51.66  ?  532 PRO B C   1 
ATOM   9345  O  O   . PRO B 1 543 ? 130.084 123.629 106.141 1.00 51.66  ?  532 PRO B O   1 
ATOM   9346  C  CB  . PRO B 1 543 ? 131.653 125.447 104.101 1.00 51.66  ?  532 PRO B CB  1 
ATOM   9347  C  CG  . PRO B 1 543 ? 131.953 126.431 105.161 1.00 51.66  ?  532 PRO B CG  1 
ATOM   9348  C  CD  . PRO B 1 543 ? 130.710 127.165 105.459 1.00 51.66  ?  532 PRO B CD  1 
ATOM   9349  N  N   . GLU B 1 544 ? 129.591 122.786 104.120 1.00 57.86  ?  533 GLU B N   1 
ATOM   9350  C  CA  . GLU B 1 544 ? 129.060 121.542 104.654 1.00 57.86  ?  533 GLU B CA  1 
ATOM   9351  C  C   . GLU B 1 544 ? 130.158 120.792 105.396 1.00 57.86  ?  533 GLU B C   1 
ATOM   9352  O  O   . GLU B 1 544 ? 131.237 120.560 104.848 1.00 57.86  ?  533 GLU B O   1 
ATOM   9353  C  CB  . GLU B 1 544 ? 128.485 120.698 103.521 1.00 57.86  ?  533 GLU B CB  1 
ATOM   9354  C  CG  . GLU B 1 544 ? 127.360 119.760 103.921 1.00 57.86  ?  533 GLU B CG  1 
ATOM   9355  C  CD  . GLU B 1 544 ? 127.837 118.479 104.560 1.00 57.86  ?  533 GLU B CD  1 
ATOM   9356  O  OE1 . GLU B 1 544 ? 128.726 117.823 103.979 1.00 57.86  ?  533 GLU B OE1 1 
ATOM   9357  O  OE2 . GLU B 1 544 ? 127.313 118.122 105.639 1.00 57.86  -1 533 GLU B OE2 1 
ATOM   9358  N  N   . GLY B 1 545 ? 129.890 120.426 106.643 1.00 49.73  ?  534 GLY B N   1 
ATOM   9359  C  CA  . GLY B 1 545 ? 130.856 119.731 107.460 1.00 49.73  ?  534 GLY B CA  1 
ATOM   9360  C  C   . GLY B 1 545 ? 131.827 120.612 108.202 1.00 49.73  ?  534 GLY B C   1 
ATOM   9361  O  O   . GLY B 1 545 ? 132.768 120.093 108.803 1.00 49.73  ?  534 GLY B O   1 
ATOM   9362  N  N   . VAL B 1 546 ? 131.631 121.922 108.184 1.00 46.85  ?  535 VAL B N   1 
ATOM   9363  C  CA  . VAL B 1 546 ? 132.512 122.873 108.842 1.00 46.85  ?  535 VAL B CA  1 
ATOM   9364  C  C   . VAL B 1 546 ? 131.726 123.598 109.920 1.00 46.85  ?  535 VAL B C   1 
ATOM   9365  O  O   . VAL B 1 546 ? 130.609 124.063 109.676 1.00 46.85  ?  535 VAL B O   1 
ATOM   9366  C  CB  . VAL B 1 546 ? 133.105 123.876 107.833 1.00 46.85  ?  535 VAL B CB  1 
ATOM   9367  C  CG1 . VAL B 1 546 ? 134.022 124.849 108.528 1.00 46.85  ?  535 VAL B CG1 1 
ATOM   9368  C  CG2 . VAL B 1 546 ? 133.837 123.147 106.740 1.00 46.85  ?  535 VAL B CG2 1 
ATOM   9369  N  N   . LYS B 1 547 ? 132.301 123.686 111.112 1.00 43.07  ?  536 LYS B N   1 
ATOM   9370  C  CA  . LYS B 1 547 ? 131.744 124.464 112.208 1.00 43.07  ?  536 LYS B CA  1 
ATOM   9371  C  C   . LYS B 1 547 ? 132.725 125.565 112.566 1.00 43.07  ?  536 LYS B C   1 
ATOM   9372  O  O   . LYS B 1 547 ? 133.922 125.311 112.692 1.00 43.07  ?  536 LYS B O   1 
ATOM   9373  C  CB  . LYS B 1 547 ? 131.468 123.590 113.431 1.00 43.07  ?  536 LYS B CB  1 
ATOM   9374  C  CG  . LYS B 1 547 ? 130.177 122.823 113.371 1.00 43.07  ?  536 LYS B CG  1 
ATOM   9375  C  CD  . LYS B 1 547 ? 129.000 123.710 113.617 1.00 43.07  ?  536 LYS B CD  1 
ATOM   9376  C  CE  . LYS B 1 547 ? 127.717 122.981 113.334 1.00 43.07  ?  536 LYS B CE  1 
ATOM   9377  N  NZ  . LYS B 1 547 ? 126.555 123.885 113.508 1.00 43.07  1  536 LYS B NZ  1 
ATOM   9378  N  N   . ILE B 1 548 ? 132.222 126.780 112.723 1.00 38.02  ?  537 ILE B N   1 
ATOM   9379  C  CA  . ILE B 1 548 ? 133.034 127.921 113.123 1.00 38.02  ?  537 ILE B CA  1 
ATOM   9380  C  C   . ILE B 1 548 ? 132.515 128.397 114.468 1.00 38.02  ?  537 ILE B C   1 
ATOM   9381  O  O   . ILE B 1 548 ? 131.381 128.865 114.574 1.00 38.02  ?  537 ILE B O   1 
ATOM   9382  C  CB  . ILE B 1 548 ? 133.002 129.042 112.078 1.00 38.02  ?  537 ILE B CB  1 
ATOM   9383  C  CG1 . ILE B 1 548 ? 133.472 128.513 110.730 1.00 38.02  ?  537 ILE B CG1 1 
ATOM   9384  C  CG2 . ILE B 1 548 ? 133.871 130.186 112.517 1.00 38.02  ?  537 ILE B CG2 1 
ATOM   9385  C  CD1 . ILE B 1 548 ? 132.866 129.209 109.577 1.00 38.02  ?  537 ILE B CD1 1 
ATOM   9386  N  N   . PHE B 1 549 ? 133.340 128.282 115.496 1.00 39.61  ?  538 PHE B N   1 
ATOM   9387  C  CA  . PHE B 1 549 ? 132.945 128.592 116.859 1.00 39.61  ?  538 PHE B CA  1 
ATOM   9388  C  C   . PHE B 1 549 ? 133.740 129.786 117.360 1.00 39.61  ?  538 PHE B C   1 
ATOM   9389  O  O   . PHE B 1 549 ? 134.956 129.843 117.182 1.00 39.61  ?  538 PHE B O   1 
ATOM   9390  C  CB  . PHE B 1 549 ? 133.167 127.381 117.763 1.00 39.61  ?  538 PHE B CB  1 
ATOM   9391  C  CG  . PHE B 1 549 ? 132.610 127.540 119.137 1.00 39.61  ?  538 PHE B CG  1 
ATOM   9392  C  CD1 . PHE B 1 549 ? 131.254 127.588 119.346 1.00 39.61  ?  538 PHE B CD1 1 
ATOM   9393  C  CD2 . PHE B 1 549 ? 133.448 127.637 120.222 1.00 39.61  ?  538 PHE B CD2 1 
ATOM   9394  C  CE1 . PHE B 1 549 ? 130.754 127.734 120.601 1.00 39.61  ?  538 PHE B CE1 1 
ATOM   9395  C  CE2 . PHE B 1 549 ? 132.944 127.781 121.475 1.00 39.61  ?  538 PHE B CE2 1 
ATOM   9396  C  CZ  . PHE B 1 549 ? 131.599 127.827 121.662 1.00 39.61  ?  538 PHE B CZ  1 
ATOM   9397  N  N   . ARG B 1 550 ? 133.056 130.730 117.990 1.00 44.02  ?  539 ARG B N   1 
ATOM   9398  C  CA  . ARG B 1 550 ? 133.678 131.936 118.511 1.00 44.02  ?  539 ARG B CA  1 
ATOM   9399  C  C   . ARG B 1 550 ? 133.408 132.045 120.003 1.00 44.02  ?  539 ARG B C   1 
ATOM   9400  O  O   . ARG B 1 550 ? 132.261 131.916 120.441 1.00 44.02  ?  539 ARG B O   1 
ATOM   9401  C  CB  . ARG B 1 550 ? 133.154 133.168 117.782 1.00 44.02  ?  539 ARG B CB  1 
ATOM   9402  C  CG  . ARG B 1 550 ? 133.656 134.456 118.336 1.00 44.02  ?  539 ARG B CG  1 
ATOM   9403  C  CD  . ARG B 1 550 ? 133.008 135.619 117.651 1.00 44.02  ?  539 ARG B CD  1 
ATOM   9404  N  NE  . ARG B 1 550 ? 133.221 136.856 118.388 1.00 44.02  ?  539 ARG B NE  1 
ATOM   9405  C  CZ  . ARG B 1 550 ? 134.274 137.646 118.232 1.00 44.02  ?  539 ARG B CZ  1 
ATOM   9406  N  NH1 . ARG B 1 550 ? 134.382 138.751 118.947 1.00 44.02  1  539 ARG B NH1 1 
ATOM   9407  N  NH2 . ARG B 1 550 ? 135.218 137.332 117.364 1.00 44.02  ?  539 ARG B NH2 1 
ATOM   9408  N  N   . CYS B 1 551 ? 134.469 132.267 120.776 1.00 48.12  ?  540 CYS B N   1 
ATOM   9409  C  CA  . CYS B 1 551 ? 134.381 132.647 122.177 1.00 48.12  ?  540 CYS B CA  1 
ATOM   9410  C  C   . CYS B 1 551 ? 134.880 134.073 122.316 1.00 48.12  ?  540 CYS B C   1 
ATOM   9411  O  O   . CYS B 1 551 ? 136.059 134.335 122.056 1.00 48.12  ?  540 CYS B O   1 
ATOM   9412  C  CB  . CYS B 1 551 ? 135.199 131.712 123.062 1.00 48.12  ?  540 CYS B CB  1 
ATOM   9413  S  SG  . CYS B 1 551 ? 135.058 132.045 124.827 1.00 48.12  ?  540 CYS B SG  1 
ATOM   9414  N  N   . PRO B 1 552 ? 134.037 135.007 122.692 1.00 46.83  ?  541 PRO B N   1 
ATOM   9415  C  CA  . PRO B 1 552 ? 134.423 136.426 122.695 1.00 46.83  ?  541 PRO B CA  1 
ATOM   9416  C  C   . PRO B 1 552 ? 135.036 136.895 124.005 1.00 46.83  ?  541 PRO B C   1 
ATOM   9417  O  O   . PRO B 1 552 ? 134.651 137.921 124.564 1.00 46.83  ?  541 PRO B O   1 
ATOM   9418  C  CB  . PRO B 1 552 ? 133.069 137.119 122.442 1.00 46.83  ?  541 PRO B CB  1 
ATOM   9419  C  CG  . PRO B 1 552 ? 132.110 136.234 123.154 1.00 46.83  ?  541 PRO B CG  1 
ATOM   9420  C  CD  . PRO B 1 552 ? 132.643 134.826 123.107 1.00 46.83  ?  541 PRO B CD  1 
ATOM   9421  N  N   . SER B 1 553 ? 135.982 136.118 124.480 1.00 45.92  ?  542 SER B N   1 
ATOM   9422  C  CA  . SER B 1 553 ? 136.578 136.388 125.746 1.00 45.92  ?  542 SER B CA  1 
ATOM   9423  C  C   . SER B 1 553 ? 137.878 135.657 125.850 1.00 45.92  ?  542 SER B C   1 
ATOM   9424  O  O   . SER B 1 553 ? 138.127 134.728 125.104 1.00 45.92  ?  542 SER B O   1 
ATOM   9425  C  CB  . SER B 1 553 ? 135.622 135.842 126.810 1.00 45.92  ?  542 SER B CB  1 
ATOM   9426  O  OG  . SER B 1 553 ? 135.991 136.200 128.111 1.00 45.92  ?  542 SER B OG  1 
ATOM   9427  N  N   . PRO B 1 554 ? 138.744 136.101 126.762 1.00 44.88  ?  543 PRO B N   1 
ATOM   9428  C  CA  . PRO B 1 554 ? 139.952 135.318 126.991 1.00 44.88  ?  543 PRO B CA  1 
ATOM   9429  C  C   . PRO B 1 554 ? 139.517 134.071 127.748 1.00 44.88  ?  543 PRO B C   1 
ATOM   9430  O  O   . PRO B 1 554 ? 138.622 134.122 128.569 1.00 44.88  ?  543 PRO B O   1 
ATOM   9431  C  CB  . PRO B 1 554 ? 140.786 136.213 127.901 1.00 44.88  ?  543 PRO B CB  1 
ATOM   9432  C  CG  . PRO B 1 554 ? 139.843 137.215 128.452 1.00 44.88  ?  543 PRO B CG  1 
ATOM   9433  C  CD  . PRO B 1 554 ? 138.811 137.420 127.401 1.00 44.88  ?  543 PRO B CD  1 
ATOM   9434  N  N   . ILE B 1 555 ? 140.149 132.951 127.480 1.00 45.87  ?  544 ILE B N   1 
ATOM   9435  C  CA  . ILE B 1 555 ? 139.786 131.730 128.141 1.00 45.87  ?  544 ILE B CA  1 
ATOM   9436  C  C   . ILE B 1 555 ? 140.825 131.463 129.207 1.00 45.87  ?  544 ILE B C   1 
ATOM   9437  O  O   . ILE B 1 555 ? 141.991 131.332 128.921 1.00 45.87  ?  544 ILE B O   1 
ATOM   9438  C  CB  . ILE B 1 555 ? 139.675 130.599 127.111 1.00 45.87  ?  544 ILE B CB  1 
ATOM   9439  C  CG1 . ILE B 1 555 ? 138.848 131.096 125.925 1.00 45.87  ?  544 ILE B CG1 1 
ATOM   9440  C  CG2 . ILE B 1 555 ? 139.035 129.366 127.720 1.00 45.87  ?  544 ILE B CG2 1 
ATOM   9441  C  CD1 . ILE B 1 555 ? 138.920 130.233 124.694 1.00 45.87  ?  544 ILE B CD1 1 
ATOM   9442  N  N   . TYR B 1 556 ? 140.384 131.415 130.454 1.00 43.81  ?  545 TYR B N   1 
ATOM   9443  C  CA  . TYR B 1 556 ? 141.270 131.185 131.579 1.00 43.81  ?  545 TYR B CA  1 
ATOM   9444  C  C   . TYR B 1 556 ? 140.649 130.167 132.510 1.00 43.81  ?  545 TYR B C   1 
ATOM   9445  O  O   . TYR B 1 556 ? 139.827 129.405 132.070 1.00 43.81  ?  545 TYR B O   1 
ATOM   9446  C  CB  . TYR B 1 556 ? 141.639 132.475 132.293 1.00 43.81  ?  545 TYR B CB  1 
ATOM   9447  C  CG  . TYR B 1 556 ? 140.452 133.233 132.762 1.00 43.81  ?  545 TYR B CG  1 
ATOM   9448  C  CD1 . TYR B 1 556 ? 139.587 133.804 131.859 1.00 43.81  ?  545 TYR B CD1 1 
ATOM   9449  C  CD2 . TYR B 1 556 ? 140.182 133.359 134.108 1.00 43.81  ?  545 TYR B CD2 1 
ATOM   9450  C  CE1 . TYR B 1 556 ? 138.486 134.481 132.281 1.00 43.81  ?  545 TYR B CE1 1 
ATOM   9451  C  CE2 . TYR B 1 556 ? 139.085 134.052 134.542 1.00 43.81  ?  545 TYR B CE2 1 
ATOM   9452  C  CZ  . TYR B 1 556 ? 138.241 134.609 133.620 1.00 43.81  ?  545 TYR B CZ  1 
ATOM   9453  O  OH  . TYR B 1 556 ? 137.135 135.296 134.032 1.00 43.81  ?  545 TYR B OH  1 
ATOM   9454  N  N   . PHE B 1 557 ? 140.941 130.198 133.804 1.00 42.72  ?  546 PHE B N   1 
ATOM   9455  C  CA  . PHE B 1 557 ? 140.452 129.084 134.614 1.00 42.72  ?  546 PHE B CA  1 
ATOM   9456  C  C   . PHE B 1 557 ? 138.959 129.156 134.903 1.00 42.72  ?  546 PHE B C   1 
ATOM   9457  O  O   . PHE B 1 557 ? 138.306 128.116 135.017 1.00 42.72  ?  546 PHE B O   1 
ATOM   9458  C  CB  . PHE B 1 557 ? 141.230 129.021 135.932 1.00 42.72  ?  546 PHE B CB  1 
ATOM   9459  C  CG  . PHE B 1 557 ? 141.089 130.250 136.785 1.00 42.72  ?  546 PHE B CG  1 
ATOM   9460  C  CD1 . PHE B 1 557 ? 141.991 131.285 136.682 1.00 42.72  ?  546 PHE B CD1 1 
ATOM   9461  C  CD2 . PHE B 1 557 ? 140.061 130.364 137.697 1.00 42.72  ?  546 PHE B CD2 1 
ATOM   9462  C  CE1 . PHE B 1 557 ? 141.859 132.404 137.455 1.00 42.72  ?  546 PHE B CE1 1 
ATOM   9463  C  CE2 . PHE B 1 557 ? 139.926 131.482 138.461 1.00 42.72  ?  546 PHE B CE2 1 
ATOM   9464  C  CZ  . PHE B 1 557 ? 140.825 132.502 138.342 1.00 42.72  ?  546 PHE B CZ  1 
ATOM   9465  N  N   . ALA B 1 558 ? 138.404 130.348 135.067 1.00 43.19  ?  547 ALA B N   1 
ATOM   9466  C  CA  . ALA B 1 558 ? 136.995 130.473 135.403 1.00 43.19  ?  547 ALA B CA  1 
ATOM   9467  C  C   . ALA B 1 558 ? 136.098 130.323 134.196 1.00 43.19  ?  547 ALA B C   1 
ATOM   9468  O  O   . ALA B 1 558 ? 134.898 130.572 134.289 1.00 43.19  ?  547 ALA B O   1 
ATOM   9469  C  CB  . ALA B 1 558 ? 136.733 131.817 136.076 1.00 43.19  ?  547 ALA B CB  1 
ATOM   9470  N  N   . ASN B 1 559 ? 136.659 129.886 133.082 1.00 43.62  ?  548 ASN B N   1 
ATOM   9471  C  CA  . ASN B 1 559 ? 136.038 129.998 131.778 1.00 43.62  ?  548 ASN B CA  1 
ATOM   9472  C  C   . ASN B 1 559 ? 136.013 128.709 130.992 1.00 43.62  ?  548 ASN B C   1 
ATOM   9473  O  O   . ASN B 1 559 ? 135.084 128.515 130.208 1.00 43.62  ?  548 ASN B O   1 
ATOM   9474  C  CB  . ASN B 1 559 ? 136.791 131.041 130.943 1.00 43.62  ?  548 ASN B CB  1 
ATOM   9475  C  CG  . ASN B 1 559 ? 135.905 132.081 130.418 1.00 43.62  ?  548 ASN B CG  1 
ATOM   9476  O  OD1 . ASN B 1 559 ? 134.699 131.948 130.489 1.00 43.62  ?  548 ASN B OD1 1 
ATOM   9477  N  ND2 . ASN B 1 559 ? 136.478 133.143 129.897 1.00 43.62  ?  548 ASN B ND2 1 
ATOM   9478  N  N   . ILE B 1 560 ? 136.992 127.829 131.169 1.00 43.83  ?  549 ILE B N   1 
ATOM   9479  C  CA  . ILE B 1 560 ? 137.270 126.816 130.166 1.00 43.83  ?  549 ILE B CA  1 
ATOM   9480  C  C   . ILE B 1 560 ? 136.262 125.673 130.212 1.00 43.83  ?  549 ILE B C   1 
ATOM   9481  O  O   . ILE B 1 560 ? 135.968 125.065 129.179 1.00 43.83  ?  549 ILE B O   1 
ATOM   9482  C  CB  . ILE B 1 560 ? 138.723 126.335 130.328 1.00 43.83  ?  549 ILE B CB  1 
ATOM   9483  C  CG1 . ILE B 1 560 ? 139.036 125.215 129.346 1.00 43.83  ?  549 ILE B CG1 1 
ATOM   9484  C  CG2 . ILE B 1 560 ? 139.018 125.948 131.764 1.00 43.83  ?  549 ILE B CG2 1 
ATOM   9485  C  CD1 . ILE B 1 560 ? 139.297 125.670 127.959 1.00 43.83  ?  549 ILE B CD1 1 
ATOM   9486  N  N   . GLY B 1 561 ? 135.695 125.374 131.379 1.00 42.53  ?  550 GLY B N   1 
ATOM   9487  C  CA  . GLY B 1 561 ? 134.632 124.387 131.431 1.00 42.53  ?  550 GLY B CA  1 
ATOM   9488  C  C   . GLY B 1 561 ? 133.389 124.840 130.694 1.00 42.53  ?  550 GLY B C   1 
ATOM   9489  O  O   . GLY B 1 561 ? 132.771 124.065 129.961 1.00 42.53  ?  550 GLY B O   1 
ATOM   9490  N  N   . PHE B 1 562 ? 133.014 126.103 130.874 1.00 42.14  ?  551 PHE B N   1 
ATOM   9491  C  CA  . PHE B 1 562 ? 131.908 126.677 130.122 1.00 42.14  ?  551 PHE B CA  1 
ATOM   9492  C  C   . PHE B 1 562 ? 132.195 126.666 128.628 1.00 42.14  ?  551 PHE B C   1 
ATOM   9493  O  O   . PHE B 1 562 ? 131.308 126.379 127.819 1.00 42.14  ?  551 PHE B O   1 
ATOM   9494  C  CB  . PHE B 1 562 ? 131.647 128.097 130.615 1.00 42.14  ?  551 PHE B CB  1 
ATOM   9495  C  CG  . PHE B 1 562 ? 130.406 128.712 130.068 1.00 42.14  ?  551 PHE B CG  1 
ATOM   9496  C  CD1 . PHE B 1 562 ? 130.449 129.484 128.931 1.00 42.14  ?  551 PHE B CD1 1 
ATOM   9497  C  CD2 . PHE B 1 562 ? 129.198 128.530 130.695 1.00 42.14  ?  551 PHE B CD2 1 
ATOM   9498  C  CE1 . PHE B 1 562 ? 129.320 130.049 128.430 1.00 42.14  ?  551 PHE B CE1 1 
ATOM   9499  C  CE2 . PHE B 1 562 ? 128.065 129.101 130.192 1.00 42.14  ?  551 PHE B CE2 1 
ATOM   9500  C  CZ  . PHE B 1 562 ? 128.127 129.859 129.061 1.00 42.14  ?  551 PHE B CZ  1 
ATOM   9501  N  N   . PHE B 1 563 ? 133.431 126.983 128.248 1.00 43.26  ?  552 PHE B N   1 
ATOM   9502  C  CA  . PHE B 1 563 ? 133.820 126.965 126.845 1.00 43.26  ?  552 PHE B CA  1 
ATOM   9503  C  C   . PHE B 1 563 ? 133.676 125.573 126.250 1.00 43.26  ?  552 PHE B C   1 
ATOM   9504  O  O   . PHE B 1 563 ? 133.173 125.419 125.134 1.00 43.26  ?  552 PHE B O   1 
ATOM   9505  C  CB  . PHE B 1 563 ? 135.255 127.474 126.711 1.00 43.26  ?  552 PHE B CB  1 
ATOM   9506  C  CG  . PHE B 1 563 ? 135.834 127.323 125.339 1.00 43.26  ?  552 PHE B CG  1 
ATOM   9507  C  CD1 . PHE B 1 563 ? 136.647 126.257 125.029 1.00 43.26  ?  552 PHE B CD1 1 
ATOM   9508  C  CD2 . PHE B 1 563 ? 135.580 128.258 124.364 1.00 43.26  ?  552 PHE B CD2 1 
ATOM   9509  C  CE1 . PHE B 1 563 ? 137.175 126.123 123.775 1.00 43.26  ?  552 PHE B CE1 1 
ATOM   9510  C  CE2 . PHE B 1 563 ? 136.110 128.124 123.113 1.00 43.26  ?  552 PHE B CE2 1 
ATOM   9511  C  CZ  . PHE B 1 563 ? 136.907 127.055 122.818 1.00 43.26  ?  552 PHE B CZ  1 
ATOM   9512  N  N   . ARG B 1 564 ? 134.105 124.546 126.982 1.00 46.33  ?  553 ARG B N   1 
ATOM   9513  C  CA  . ARG B 1 564 ? 133.979 123.181 126.488 1.00 46.33  ?  553 ARG B CA  1 
ATOM   9514  C  C   . ARG B 1 564 ? 132.521 122.767 126.359 1.00 46.33  ?  553 ARG B C   1 
ATOM   9515  O  O   . ARG B 1 564 ? 132.129 122.135 125.371 1.00 46.33  ?  553 ARG B O   1 
ATOM   9516  C  CB  . ARG B 1 564 ? 134.726 122.227 127.409 1.00 46.33  ?  553 ARG B CB  1 
ATOM   9517  C  CG  . ARG B 1 564 ? 134.833 120.825 126.871 1.00 46.33  ?  553 ARG B CG  1 
ATOM   9518  C  CD  . ARG B 1 564 ? 135.202 119.837 127.953 1.00 46.33  ?  553 ARG B CD  1 
ATOM   9519  N  NE  . ARG B 1 564 ? 135.998 118.736 127.425 1.00 46.33  ?  553 ARG B NE  1 
ATOM   9520  C  CZ  . ARG B 1 564 ? 137.325 118.691 127.456 1.00 46.33  ?  553 ARG B CZ  1 
ATOM   9521  N  NH1 . ARG B 1 564 ? 137.961 117.650 126.951 1.00 46.33  1  553 ARG B NH1 1 
ATOM   9522  N  NH2 . ARG B 1 564 ? 138.017 119.684 127.993 1.00 46.33  ?  553 ARG B NH2 1 
ATOM   9523  N  N   . ARG B 1 565 ? 131.701 123.111 127.352 1.00 44.86  ?  554 ARG B N   1 
ATOM   9524  C  CA  . ARG B 1 565 ? 130.275 122.820 127.268 1.00 44.86  ?  554 ARG B CA  1 
ATOM   9525  C  C   . ARG B 1 565 ? 129.646 123.471 126.046 1.00 44.86  ?  554 ARG B C   1 
ATOM   9526  O  O   . ARG B 1 565 ? 128.877 122.835 125.318 1.00 44.86  ?  554 ARG B O   1 
ATOM   9527  C  CB  . ARG B 1 565 ? 129.575 123.297 128.533 1.00 44.86  ?  554 ARG B CB  1 
ATOM   9528  C  CG  . ARG B 1 565 ? 129.173 122.204 129.473 1.00 44.86  ?  554 ARG B CG  1 
ATOM   9529  C  CD  . ARG B 1 565 ? 128.535 122.778 130.720 1.00 44.86  ?  554 ARG B CD  1 
ATOM   9530  N  NE  . ARG B 1 565 ? 129.536 123.157 131.711 1.00 44.86  ?  554 ARG B NE  1 
ATOM   9531  C  CZ  . ARG B 1 565 ? 129.595 124.347 132.295 1.00 44.86  ?  554 ARG B CZ  1 
ATOM   9532  N  NH1 . ARG B 1 565 ? 130.542 124.603 133.184 1.00 44.86  1  554 ARG B NH1 1 
ATOM   9533  N  NH2 . ARG B 1 565 ? 128.702 125.276 131.994 1.00 44.86  ?  554 ARG B NH2 1 
ATOM   9534  N  N   . LYS B 1 566 ? 129.969 124.737 125.799 1.00 43.08  ?  555 LYS B N   1 
ATOM   9535  C  CA  . LYS B 1 566 ? 129.369 125.451 124.681 1.00 43.08  ?  555 LYS B CA  1 
ATOM   9536  C  C   . LYS B 1 566 ? 129.862 124.917 123.347 1.00 43.08  ?  555 LYS B C   1 
ATOM   9537  O  O   . LYS B 1 566 ? 129.094 124.842 122.387 1.00 43.08  ?  555 LYS B O   1 
ATOM   9538  C  CB  . LYS B 1 566 ? 129.660 126.939 124.802 1.00 43.08  ?  555 LYS B CB  1 
ATOM   9539  C  CG  . LYS B 1 566 ? 128.934 127.591 125.930 1.00 43.08  ?  555 LYS B CG  1 
ATOM   9540  C  CD  . LYS B 1 566 ? 127.454 127.447 125.757 1.00 43.08  ?  555 LYS B CD  1 
ATOM   9541  C  CE  . LYS B 1 566 ? 126.771 127.264 127.080 1.00 43.08  ?  555 LYS B CE  1 
ATOM   9542  N  NZ  . LYS B 1 566 ? 125.307 127.433 126.948 1.00 43.08  1  555 LYS B NZ  1 
ATOM   9543  N  N   . LEU B 1 567 ? 131.131 124.533 123.263 1.00 42.49  ?  556 LEU B N   1 
ATOM   9544  C  CA  . LEU B 1 567 ? 131.643 123.974 122.021 1.00 42.49  ?  556 LEU B CA  1 
ATOM   9545  C  C   . LEU B 1 567 ? 131.001 122.630 121.720 1.00 42.49  ?  556 LEU B C   1 
ATOM   9546  O  O   . LEU B 1 567 ? 130.689 122.328 120.563 1.00 42.49  ?  556 LEU B O   1 
ATOM   9547  C  CB  . LEU B 1 567 ? 133.160 123.848 122.100 1.00 42.49  ?  556 LEU B CB  1 
ATOM   9548  C  CG  . LEU B 1 567 ? 133.905 123.232 120.922 1.00 42.49  ?  556 LEU B CG  1 
ATOM   9549  C  CD1 . LEU B 1 567 ? 133.636 124.010 119.665 1.00 42.49  ?  556 LEU B CD1 1 
ATOM   9550  C  CD2 . LEU B 1 567 ? 135.376 123.195 121.219 1.00 42.49  ?  556 LEU B CD2 1 
ATOM   9551  N  N   . ILE B 1 568 ? 130.788 121.812 122.748 1.00 44.39  ?  557 ILE B N   1 
ATOM   9552  C  CA  . ILE B 1 568 ? 130.144 120.522 122.540 1.00 44.39  ?  557 ILE B CA  1 
ATOM   9553  C  C   . ILE B 1 568 ? 128.678 120.707 122.170 1.00 44.39  ?  557 ILE B C   1 
ATOM   9554  O  O   . ILE B 1 568 ? 128.123 119.935 121.384 1.00 44.39  ?  557 ILE B O   1 
ATOM   9555  C  CB  . ILE B 1 568 ? 130.336 119.641 123.785 1.00 44.39  ?  557 ILE B CB  1 
ATOM   9556  C  CG1 . ILE B 1 568 ? 131.721 119.009 123.750 1.00 44.39  ?  557 ILE B CG1 1 
ATOM   9557  C  CG2 . ILE B 1 568 ? 129.285 118.570 123.873 1.00 44.39  ?  557 ILE B CG2 1 
ATOM   9558  C  CD1 . ILE B 1 568 ? 132.116 118.363 125.031 1.00 44.39  ?  557 ILE B CD1 1 
ATOM   9559  N  N   . ASP B 1 569 ? 128.033 121.745 122.700 1.00 47.88  ?  558 ASP B N   1 
ATOM   9560  C  CA  . ASP B 1 569 ? 126.671 122.048 122.271 1.00 47.88  ?  558 ASP B CA  1 
ATOM   9561  C  C   . ASP B 1 569 ? 126.638 122.571 120.842 1.00 47.88  ?  558 ASP B C   1 
ATOM   9562  O  O   . ASP B 1 569 ? 125.658 122.364 120.121 1.00 47.88  ?  558 ASP B O   1 
ATOM   9563  C  CB  . ASP B 1 569 ? 126.033 123.060 123.214 1.00 47.88  ?  558 ASP B CB  1 
ATOM   9564  C  CG  . ASP B 1 569 ? 125.770 122.492 124.580 1.00 47.88  ?  558 ASP B CG  1 
ATOM   9565  O  OD1 . ASP B 1 569 ? 125.642 123.283 125.536 1.00 47.88  ?  558 ASP B OD1 1 
ATOM   9566  O  OD2 . ASP B 1 569 ? 125.690 121.252 124.707 1.00 47.88  -1 558 ASP B OD2 1 
ATOM   9567  N  N   . ALA B 1 570 ? 127.692 123.266 120.420 1.00 44.37  ?  559 ALA B N   1 
ATOM   9568  C  CA  . ALA B 1 570 ? 127.720 123.836 119.080 1.00 44.37  ?  559 ALA B CA  1 
ATOM   9569  C  C   . ALA B 1 570 ? 127.961 122.773 118.019 1.00 44.37  ?  559 ALA B C   1 
ATOM   9570  O  O   . ALA B 1 570 ? 127.311 122.786 116.971 1.00 44.37  ?  559 ALA B O   1 
ATOM   9571  C  CB  . ALA B 1 570 ? 128.786 124.922 118.995 1.00 44.37  ?  559 ALA B CB  1 
ATOM   9572  N  N   . VAL B 1 571 ? 128.896 121.852 118.255 1.00 44.61  ?  560 VAL B N   1 
ATOM   9573  C  CA  . VAL B 1 571 ? 129.141 120.833 117.240 1.00 44.61  ?  560 VAL B CA  1 
ATOM   9574  C  C   . VAL B 1 571 ? 128.071 119.753 117.262 1.00 44.61  ?  560 VAL B C   1 
ATOM   9575  O  O   . VAL B 1 571 ? 127.884 119.054 116.263 1.00 44.61  ?  560 VAL B O   1 
ATOM   9576  C  CB  . VAL B 1 571 ? 130.540 120.211 117.379 1.00 44.61  ?  560 VAL B CB  1 
ATOM   9577  C  CG1 . VAL B 1 571 ? 131.598 121.277 117.289 1.00 44.61  ?  560 VAL B CG1 1 
ATOM   9578  C  CG2 . VAL B 1 571 ? 130.667 119.431 118.663 1.00 44.61  ?  560 VAL B CG2 1 
ATOM   9579  N  N   . GLY B 1 572 ? 127.355 119.597 118.369 1.00 45.74  ?  561 GLY B N   1 
ATOM   9580  C  CA  . GLY B 1 572 ? 126.250 118.671 118.443 1.00 45.74  ?  561 GLY B CA  1 
ATOM   9581  C  C   . GLY B 1 572 ? 126.580 117.302 118.986 1.00 45.74  ?  561 GLY B C   1 
ATOM   9582  O  O   . GLY B 1 572 ? 125.696 116.443 119.018 1.00 45.74  ?  561 GLY B O   1 
ATOM   9583  N  N   . PHE B 1 573 ? 127.815 117.066 119.406 1.00 47.18  ?  562 PHE B N   1 
ATOM   9584  C  CA  . PHE B 1 573 ? 128.209 115.786 119.969 1.00 47.18  ?  562 PHE B CA  1 
ATOM   9585  C  C   . PHE B 1 573 ? 129.409 116.018 120.868 1.00 47.18  ?  562 PHE B C   1 
ATOM   9586  O  O   . PHE B 1 573 ? 130.020 117.085 120.855 1.00 47.18  ?  562 PHE B O   1 
ATOM   9587  C  CB  . PHE B 1 573 ? 128.537 114.763 118.878 1.00 47.18  ?  562 PHE B CB  1 
ATOM   9588  C  CG  . PHE B 1 573 ? 129.592 115.221 117.924 1.00 47.18  ?  562 PHE B CG  1 
ATOM   9589  C  CD1 . PHE B 1 573 ? 130.923 115.026 118.201 1.00 47.18  ?  562 PHE B CD1 1 
ATOM   9590  C  CD2 . PHE B 1 573 ? 129.250 115.863 116.759 1.00 47.18  ?  562 PHE B CD2 1 
ATOM   9591  C  CE1 . PHE B 1 573 ? 131.878 115.464 117.342 1.00 47.18  ?  562 PHE B CE1 1 
ATOM   9592  C  CE2 . PHE B 1 573 ? 130.209 116.292 115.896 1.00 47.18  ?  562 PHE B CE2 1 
ATOM   9593  C  CZ  . PHE B 1 573 ? 131.524 116.090 116.185 1.00 47.18  ?  562 PHE B CZ  1 
ATOM   9594  N  N   . SER B 1 574 ? 129.747 114.999 121.644 1.00 49.45  ?  563 SER B N   1 
ATOM   9595  C  CA  . SER B 1 574 ? 130.955 115.017 122.444 1.00 49.45  ?  563 SER B CA  1 
ATOM   9596  C  C   . SER B 1 574 ? 132.005 114.169 121.754 1.00 49.45  ?  563 SER B C   1 
ATOM   9597  O  O   . SER B 1 574 ? 131.765 112.977 121.533 1.00 49.45  ?  563 SER B O   1 
ATOM   9598  C  CB  . SER B 1 574 ? 130.682 114.486 123.843 1.00 49.45  ?  563 SER B CB  1 
ATOM   9599  O  OG  . SER B 1 574 ? 131.868 114.409 124.603 1.00 49.45  ?  563 SER B OG  1 
ATOM   9600  N  N   . PRO B 1 575 ? 133.158 114.724 121.377 1.00 50.31  ?  564 PRO B N   1 
ATOM   9601  C  CA  . PRO B 1 575 ? 134.156 113.922 120.656 1.00 50.31  ?  564 PRO B CA  1 
ATOM   9602  C  C   . PRO B 1 575 ? 134.727 112.768 121.458 1.00 50.31  ?  564 PRO B C   1 
ATOM   9603  O  O   . PRO B 1 575 ? 135.096 111.752 120.860 1.00 50.31  ?  564 PRO B O   1 
ATOM   9604  C  CB  . PRO B 1 575 ? 135.240 114.947 120.296 1.00 50.31  ?  564 PRO B CB  1 
ATOM   9605  C  CG  . PRO B 1 575 ? 134.995 116.096 121.168 1.00 50.31  ?  564 PRO B CG  1 
ATOM   9606  C  CD  . PRO B 1 575 ? 133.541 116.139 121.440 1.00 50.31  ?  564 PRO B CD  1 
ATOM   9607  N  N   . LEU B 1 576 ? 134.807 112.877 122.779 1.00 52.57  ?  565 LEU B N   1 
ATOM   9608  C  CA  . LEU B 1 576 ? 135.272 111.769 123.599 1.00 52.57  ?  565 LEU B CA  1 
ATOM   9609  C  C   . LEU B 1 576 ? 134.279 110.617 123.622 1.00 52.57  ?  565 LEU B C   1 
ATOM   9610  O  O   . LEU B 1 576 ? 134.681 109.452 123.598 1.00 52.57  ?  565 LEU B O   1 
ATOM   9611  C  CB  . LEU B 1 576 ? 135.549 112.254 125.020 1.00 52.57  ?  565 LEU B CB  1 
ATOM   9612  C  CG  . LEU B 1 576 ? 136.258 111.286 125.959 1.00 52.57  ?  565 LEU B CG  1 
ATOM   9613  C  CD1 . LEU B 1 576 ? 137.559 110.810 125.366 1.00 52.57  ?  565 LEU B CD1 1 
ATOM   9614  C  CD2 . LEU B 1 576 ? 136.496 111.957 127.280 1.00 52.57  ?  565 LEU B CD2 1 
ATOM   9615  N  N   . ARG B 1 577 ? 132.985 110.922 123.649 1.00 54.08  ?  566 ARG B N   1 
ATOM   9616  C  CA  . ARG B 1 577 ? 131.974 109.877 123.560 1.00 54.08  ?  566 ARG B CA  1 
ATOM   9617  C  C   . ARG B 1 577 ? 132.051 109.145 122.229 1.00 54.08  ?  566 ARG B C   1 
ATOM   9618  O  O   . ARG B 1 577 ? 131.940 107.915 122.178 1.00 54.08  ?  566 ARG B O   1 
ATOM   9619  C  CB  . ARG B 1 577 ? 130.594 110.487 123.758 1.00 54.08  ?  566 ARG B CB  1 
ATOM   9620  C  CG  . ARG B 1 577 ? 129.489 109.483 123.897 1.00 54.08  ?  566 ARG B CG  1 
ATOM   9621  C  CD  . ARG B 1 577 ? 128.278 110.129 124.500 1.00 54.08  ?  566 ARG B CD  1 
ATOM   9622  N  NE  . ARG B 1 577 ? 128.657 111.055 125.555 1.00 54.08  ?  566 ARG B NE  1 
ATOM   9623  C  CZ  . ARG B 1 577 ? 127.891 112.046 125.988 1.00 54.08  ?  566 ARG B CZ  1 
ATOM   9624  N  NH1 . ARG B 1 577 ? 126.700 112.243 125.451 1.00 54.08  1  566 ARG B NH1 1 
ATOM   9625  N  NH2 . ARG B 1 577 ? 128.317 112.840 126.955 1.00 54.08  ?  566 ARG B NH2 1 
ATOM   9626  N  N   . ILE B 1 578 ? 132.248 109.887 121.141 1.00 53.84  ?  567 ILE B N   1 
ATOM   9627  C  CA  . ILE B 1 578 ? 132.378 109.270 119.827 1.00 53.84  ?  567 ILE B CA  1 
ATOM   9628  C  C   . ILE B 1 578 ? 133.622 108.399 119.770 1.00 53.84  ?  567 ILE B C   1 
ATOM   9629  O  O   . ILE B 1 578 ? 133.596 107.295 119.220 1.00 53.84  ?  567 ILE B O   1 
ATOM   9630  C  CB  . ILE B 1 578 ? 132.395 110.348 118.729 1.00 53.84  ?  567 ILE B CB  1 
ATOM   9631  C  CG1 . ILE B 1 578 ? 131.161 111.234 118.832 1.00 53.84  ?  567 ILE B CG1 1 
ATOM   9632  C  CG2 . ILE B 1 578 ? 132.454 109.708 117.368 1.00 53.84  ?  567 ILE B CG2 1 
ATOM   9633  C  CD1 . ILE B 1 578 ? 129.916 110.582 118.342 1.00 53.84  ?  567 ILE B CD1 1 
ATOM   9634  N  N   . LEU B 1 579 ? 134.729 108.879 120.331 1.00 55.51  ?  568 LEU B N   1 
ATOM   9635  C  CA  . LEU B 1 579 ? 135.950 108.085 120.328 1.00 55.51  ?  568 LEU B CA  1 
ATOM   9636  C  C   . LEU B 1 579 ? 135.782 106.807 121.132 1.00 55.51  ?  568 LEU B C   1 
ATOM   9637  O  O   . LEU B 1 579 ? 136.265 105.747 120.726 1.00 55.51  ?  568 LEU B O   1 
ATOM   9638  C  CB  . LEU B 1 579 ? 137.109 108.905 120.872 1.00 55.51  ?  568 LEU B CB  1 
ATOM   9639  C  CG  . LEU B 1 579 ? 138.416 108.143 121.033 1.00 55.51  ?  568 LEU B CG  1 
ATOM   9640  C  CD1 . LEU B 1 579 ? 139.028 107.831 119.691 1.00 55.51  ?  568 LEU B CD1 1 
ATOM   9641  C  CD2 . LEU B 1 579 ? 139.360 108.935 121.885 1.00 55.51  ?  568 LEU B CD2 1 
ATOM   9642  N  N   . ARG B 1 580 ? 135.097 106.873 122.260 1.00 56.03  ?  569 ARG B N   1 
ATOM   9643  C  CA  . ARG B 1 580 ? 134.943 105.695 123.097 1.00 56.03  ?  569 ARG B CA  1 
ATOM   9644  C  C   . ARG B 1 580 ? 134.087 104.652 122.399 1.00 56.03  ?  569 ARG B C   1 
ATOM   9645  O  O   . ARG B 1 580 ? 134.404 103.468 122.433 1.00 56.03  ?  569 ARG B O   1 
ATOM   9646  C  CB  . ARG B 1 580 ? 134.362 106.088 124.454 1.00 56.03  ?  569 ARG B CB  1 
ATOM   9647  C  CG  . ARG B 1 580 ? 135.349 106.844 125.323 1.00 56.03  ?  569 ARG B CG  1 
ATOM   9648  C  CD  . ARG B 1 580 ? 134.680 107.453 126.539 1.00 56.03  ?  569 ARG B CD  1 
ATOM   9649  N  NE  . ARG B 1 580 ? 135.658 108.044 127.444 1.00 56.03  ?  569 ARG B NE  1 
ATOM   9650  C  CZ  . ARG B 1 580 ? 135.346 108.693 128.560 1.00 56.03  ?  569 ARG B CZ  1 
ATOM   9651  N  NH1 . ARG B 1 580 ? 134.077 108.843 128.906 1.00 56.03  1  569 ARG B NH1 1 
ATOM   9652  N  NH2 . ARG B 1 580 ? 136.303 109.197 129.325 1.00 56.03  ?  569 ARG B NH2 1 
ATOM   9653  N  N   . LYS B 1 581 ? 133.016 105.086 121.748 1.00 59.26  ?  570 LYS B N   1 
ATOM   9654  C  CA  . LYS B 1 581 ? 132.142 104.164 121.026 1.00 59.26  ?  570 LYS B CA  1 
ATOM   9655  C  C   . LYS B 1 581 ? 132.826 103.523 119.825 1.00 59.26  ?  570 LYS B C   1 
ATOM   9656  O  O   . LYS B 1 581 ? 132.587 102.358 119.523 1.00 59.26  ?  570 LYS B O   1 
ATOM   9657  C  CB  . LYS B 1 581 ? 130.866 104.875 120.591 1.00 59.26  ?  570 LYS B CB  1 
ATOM   9658  C  CG  . LYS B 1 581 ? 130.026 105.358 121.757 1.00 59.26  ?  570 LYS B CG  1 
ATOM   9659  C  CD  . LYS B 1 581 ? 128.808 106.126 121.283 1.00 59.26  ?  570 LYS B CD  1 
ATOM   9660  C  CE  . LYS B 1 581 ? 127.929 106.532 122.453 1.00 59.26  ?  570 LYS B CE  1 
ATOM   9661  N  NZ  . LYS B 1 581 ? 126.738 107.307 122.010 1.00 59.26  1  570 LYS B NZ  1 
ATOM   9662  N  N   . ARG B 1 582 ? 133.674 104.273 119.138 1.00 60.89  ?  571 ARG B N   1 
ATOM   9663  C  CA  . ARG B 1 582 ? 134.412 103.720 118.010 1.00 60.89  ?  571 ARG B CA  1 
ATOM   9664  C  C   . ARG B 1 582 ? 135.426 102.700 118.472 1.00 60.89  ?  571 ARG B C   1 
ATOM   9665  O  O   . ARG B 1 582 ? 135.651 101.699 117.803 1.00 60.89  ?  571 ARG B O   1 
ATOM   9666  C  CB  . ARG B 1 582 ? 135.116 104.827 117.239 1.00 60.89  ?  571 ARG B CB  1 
ATOM   9667  C  CG  . ARG B 1 582 ? 134.186 105.771 116.511 1.00 60.89  ?  571 ARG B CG  1 
ATOM   9668  C  CD  . ARG B 1 582 ? 134.999 106.746 115.690 1.00 60.89  ?  571 ARG B CD  1 
ATOM   9669  N  NE  . ARG B 1 582 ? 134.158 107.691 114.973 1.00 60.89  ?  571 ARG B NE  1 
ATOM   9670  C  CZ  . ARG B 1 582 ? 134.632 108.626 114.163 1.00 60.89  ?  571 ARG B CZ  1 
ATOM   9671  N  NH1 . ARG B 1 582 ? 135.937 108.726 113.973 1.00 60.89  1  571 ARG B NH1 1 
ATOM   9672  N  NH2 . ARG B 1 582 ? 133.806 109.453 113.546 1.00 60.89  ?  571 ARG B NH2 1 
ATOM   9673  N  N   . ASN B 1 583 ? 136.052 102.954 119.611 1.00 61.87  ?  572 ASN B N   1 
ATOM   9674  C  CA  . ASN B 1 583 ? 137.014 102.013 120.160 1.00 61.87  ?  572 ASN B CA  1 
ATOM   9675  C  C   . ASN B 1 583 ? 136.300 100.736 120.564 1.00 61.87  ?  572 ASN B C   1 
ATOM   9676  O  O   . ASN B 1 583 ? 136.827 99.646  120.375 1.00 61.87  ?  572 ASN B O   1 
ATOM   9677  C  CB  . ASN B 1 583 ? 137.750 102.630 121.344 1.00 61.87  ?  572 ASN B CB  1 
ATOM   9678  C  CG  . ASN B 1 583 ? 139.015 103.349 120.933 1.00 61.87  ?  572 ASN B CG  1 
ATOM   9679  O  OD1 . ASN B 1 583 ? 139.763 102.870 120.085 1.00 61.87  ?  572 ASN B OD1 1 
ATOM   9680  N  ND2 . ASN B 1 583 ? 139.270 104.497 121.546 1.00 61.87  ?  572 ASN B ND2 1 
ATOM   9681  N  N   . LYS B 1 584 ? 135.098 100.859 121.107 1.00 64.39  ?  573 LYS B N   1 
ATOM   9682  C  CA  . LYS B 1 584 ? 134.325 99.679  121.448 1.00 64.39  ?  573 LYS B CA  1 
ATOM   9683  C  C   . LYS B 1 584 ? 133.986 98.888  120.205 1.00 64.39  ?  573 LYS B C   1 
ATOM   9684  O  O   . LYS B 1 584 ? 134.109 97.667  120.190 1.00 64.39  ?  573 LYS B O   1 
ATOM   9685  C  CB  . LYS B 1 584 ? 133.045 100.069 122.178 1.00 64.39  ?  573 LYS B CB  1 
ATOM   9686  C  CG  . LYS B 1 584 ? 133.256 100.477 123.623 1.00 64.39  ?  573 LYS B CG  1 
ATOM   9687  C  CD  . LYS B 1 584 ? 131.935 100.784 124.307 1.00 64.39  ?  573 LYS B CD  1 
ATOM   9688  C  CE  . LYS B 1 584 ? 131.393 102.142 123.895 1.00 64.39  ?  573 LYS B CE  1 
ATOM   9689  N  NZ  . LYS B 1 584 ? 132.213 103.256 124.445 1.00 64.39  1  573 LYS B NZ  1 
ATOM   9690  N  N   . ALA B 1 585 ? 133.564 99.576  119.154 1.00 69.31  ?  574 ALA B N   1 
ATOM   9691  C  CA  . ALA B 1 585 ? 133.248 98.905  117.908 1.00 69.31  ?  574 ALA B CA  1 
ATOM   9692  C  C   . ALA B 1 585 ? 134.466 98.190  117.377 1.00 69.31  ?  574 ALA B C   1 
ATOM   9693  O  O   . ALA B 1 585 ? 134.379 97.045  116.958 1.00 69.31  ?  574 ALA B O   1 
ATOM   9694  C  CB  . ALA B 1 585 ? 132.753 99.909  116.897 1.00 69.31  ?  574 ALA B CB  1 
ATOM   9695  N  N   . LEU B 1 586 ? 135.608 98.859  117.400 1.00 74.84  ?  575 LEU B N   1 
ATOM   9696  C  CA  . LEU B 1 586 ? 136.818 98.266  116.864 1.00 74.84  ?  575 LEU B CA  1 
ATOM   9697  C  C   . LEU B 1 586 ? 137.187 97.033  117.662 1.00 74.84  ?  575 LEU B C   1 
ATOM   9698  O  O   . LEU B 1 586 ? 137.633 96.037  117.101 1.00 74.84  ?  575 LEU B O   1 
ATOM   9699  C  CB  . LEU B 1 586 ? 137.963 99.272  116.875 1.00 74.84  ?  575 LEU B CB  1 
ATOM   9700  C  CG  . LEU B 1 586 ? 139.277 98.772  116.279 1.00 74.84  ?  575 LEU B CG  1 
ATOM   9701  C  CD1 . LEU B 1 586 ? 139.057 98.280  114.857 1.00 74.84  ?  575 LEU B CD1 1 
ATOM   9702  C  CD2 . LEU B 1 586 ? 140.335 99.863  116.319 1.00 74.84  ?  575 LEU B CD2 1 
ATOM   9703  N  N   . ARG B 1 587 ? 136.997 97.088  118.973 1.00 78.02  ?  576 ARG B N   1 
ATOM   9704  C  CA  . ARG B 1 587 ? 137.289 95.936  119.810 1.00 78.02  ?  576 ARG B CA  1 
ATOM   9705  C  C   . ARG B 1 587 ? 136.420 94.750  119.427 1.00 78.02  ?  576 ARG B C   1 
ATOM   9706  O  O   . ARG B 1 587 ? 136.917 93.637  119.287 1.00 78.02  ?  576 ARG B O   1 
ATOM   9707  C  CB  . ARG B 1 587 ? 137.092 96.279  121.283 1.00 78.02  ?  576 ARG B CB  1 
ATOM   9708  C  CG  . ARG B 1 587 ? 138.241 97.062  121.887 1.00 78.02  ?  576 ARG B CG  1 
ATOM   9709  C  CD  . ARG B 1 587 ? 138.028 97.291  123.372 1.00 78.02  ?  576 ARG B CD  1 
ATOM   9710  N  NE  . ARG B 1 587 ? 139.295 97.278  124.093 1.00 78.02  ?  576 ARG B NE  1 
ATOM   9711  C  CZ  . ARG B 1 587 ? 139.821 96.194  124.655 1.00 78.02  ?  576 ARG B CZ  1 
ATOM   9712  N  NH1 . ARG B 1 587 ? 139.182 95.035  124.588 1.00 78.02  1  576 ARG B NH1 1 
ATOM   9713  N  NH2 . ARG B 1 587 ? 140.982 96.269  125.287 1.00 78.02  ?  576 ARG B NH2 1 
ATOM   9714  N  N   . LYS B 1 588 ? 135.130 94.984  119.244 1.00 82.06  ?  577 LYS B N   1 
ATOM   9715  C  CA  . LYS B 1 588 ? 134.241 93.909  118.840 1.00 82.06  ?  577 LYS B CA  1 
ATOM   9716  C  C   . LYS B 1 588 ? 134.689 93.351  117.508 1.00 82.06  ?  577 LYS B C   1 
ATOM   9717  O  O   . LYS B 1 588 ? 134.730 92.140  117.320 1.00 82.06  ?  577 LYS B O   1 
ATOM   9718  C  CB  . LYS B 1 588 ? 132.798 94.397  118.743 1.00 82.06  ?  577 LYS B CB  1 
ATOM   9719  C  CG  . LYS B 1 588 ? 131.839 93.366  118.175 1.00 82.06  ?  577 LYS B CG  1 
ATOM   9720  C  CD  . LYS B 1 588 ? 130.399 93.830  118.295 1.00 82.06  ?  577 LYS B CD  1 
ATOM   9721  C  CE  . LYS B 1 588 ? 130.008 94.019  119.751 1.00 82.06  ?  577 LYS B CE  1 
ATOM   9722  N  NZ  . LYS B 1 588 ? 128.581 94.417  119.898 1.00 82.06  1  577 LYS B NZ  1 
ATOM   9723  N  N   . ILE B 1 589 ? 135.042 94.231  116.584 1.00 85.38  ?  578 ILE B N   1 
ATOM   9724  C  CA  . ILE B 1 589 ? 135.463 93.796  115.267 1.00 85.38  ?  578 ILE B CA  1 
ATOM   9725  C  C   . ILE B 1 589 ? 136.660 92.885  115.367 1.00 85.38  ?  578 ILE B C   1 
ATOM   9726  O  O   . ILE B 1 589 ? 136.662 91.795  114.806 1.00 85.38  ?  578 ILE B O   1 
ATOM   9727  C  CB  . ILE B 1 589 ? 135.845 94.999  114.389 1.00 85.38  ?  578 ILE B CB  1 
ATOM   9728  C  CG1 . ILE B 1 589 ? 134.603 95.828  114.060 1.00 85.38  ?  578 ILE B CG1 1 
ATOM   9729  C  CG2 . ILE B 1 589 ? 136.536 94.538  113.116 1.00 85.38  ?  578 ILE B CG2 1 
ATOM   9730  C  CD1 . ILE B 1 589 ? 134.909 97.147  113.389 1.00 85.38  ?  578 ILE B CD1 1 
ATOM   9731  N  N   . ARG B 1 590 ? 137.678 93.321  116.094 1.00 87.72  ?  579 ARG B N   1 
ATOM   9732  C  CA  . ARG B 1 590 ? 138.892 92.535  116.199 1.00 87.72  ?  579 ARG B CA  1 
ATOM   9733  C  C   . ARG B 1 590 ? 138.589 91.194  116.845 1.00 87.72  ?  579 ARG B C   1 
ATOM   9734  O  O   . ARG B 1 590 ? 139.158 90.177  116.459 1.00 87.72  ?  579 ARG B O   1 
ATOM   9735  C  CB  . ARG B 1 590 ? 139.953 93.315  116.968 1.00 87.72  ?  579 ARG B CB  1 
ATOM   9736  C  CG  . ARG B 1 590 ? 140.353 94.599  116.264 1.00 87.72  ?  579 ARG B CG  1 
ATOM   9737  C  CD  . ARG B 1 590 ? 141.471 95.333  116.980 1.00 87.72  ?  579 ARG B CD  1 
ATOM   9738  N  NE  . ARG B 1 590 ? 141.995 96.418  116.158 1.00 87.72  ?  579 ARG B NE  1 
ATOM   9739  C  CZ  . ARG B 1 590 ? 142.976 97.234  116.527 1.00 87.72  ?  579 ARG B CZ  1 
ATOM   9740  N  NH1 . ARG B 1 590 ? 143.548 97.094  117.714 1.00 87.72  1  579 ARG B NH1 1 
ATOM   9741  N  NH2 . ARG B 1 590 ? 143.386 98.192  115.707 1.00 87.72  ?  579 ARG B NH2 1 
ATOM   9742  N  N   . LYS B 1 591 ? 137.686 91.181  117.816 1.00 93.11  ?  580 LYS B N   1 
ATOM   9743  C  CA  . LYS B 1 591 ? 137.286 89.927  118.444 1.00 93.11  ?  580 LYS B CA  1 
ATOM   9744  C  C   . LYS B 1 591 ? 136.622 88.992  117.443 1.00 93.11  ?  580 LYS B C   1 
ATOM   9745  O  O   . LYS B 1 591 ? 136.973 87.821  117.365 1.00 93.11  ?  580 LYS B O   1 
ATOM   9746  C  CB  . LYS B 1 591 ? 136.344 90.214  119.609 1.00 93.11  ?  580 LYS B CB  1 
ATOM   9747  C  CG  . LYS B 1 591 ? 135.370 89.095  119.934 1.00 93.11  ?  580 LYS B CG  1 
ATOM   9748  C  CD  . LYS B 1 591 ? 134.398 89.532  121.017 1.00 93.11  ?  580 LYS B CD  1 
ATOM   9749  C  CE  . LYS B 1 591 ? 133.253 88.545  121.169 1.00 93.11  ?  580 LYS B CE  1 
ATOM   9750  N  NZ  . LYS B 1 591 ? 132.464 88.422  119.913 1.00 93.11  1  580 LYS B NZ  1 
ATOM   9751  N  N   . LEU B 1 592 ? 135.669 89.504  116.670 1.00 97.01  ?  581 LEU B N   1 
ATOM   9752  C  CA  . LEU B 1 592 ? 135.000 88.693  115.660 1.00 97.01  ?  581 LEU B CA  1 
ATOM   9753  C  C   . LEU B 1 592 ? 135.991 88.218  114.619 1.00 97.01  ?  581 LEU B C   1 
ATOM   9754  O  O   . LEU B 1 592 ? 135.890 87.099  114.124 1.00 97.01  ?  581 LEU B O   1 
ATOM   9755  C  CB  . LEU B 1 592 ? 133.893 89.493  114.988 1.00 97.01  ?  581 LEU B CB  1 
ATOM   9756  C  CG  . LEU B 1 592 ? 132.815 90.037  115.922 1.00 97.01  ?  581 LEU B CG  1 
ATOM   9757  C  CD1 . LEU B 1 592 ? 131.886 90.984  115.179 1.00 97.01  ?  581 LEU B CD1 1 
ATOM   9758  C  CD2 . LEU B 1 592 ? 132.040 88.897  116.561 1.00 97.01  ?  581 LEU B CD2 1 
ATOM   9759  N  N   . GLN B 1 593 ? 136.944 89.069  114.271 1.00 99.73  ?  582 GLN B N   1 
ATOM   9760  C  CA  . GLN B 1 593 ? 137.966 88.685  113.316 1.00 99.73  ?  582 GLN B CA  1 
ATOM   9761  C  C   . GLN B 1 593 ? 138.795 87.553  113.889 1.00 99.73  ?  582 GLN B C   1 
ATOM   9762  O  O   . GLN B 1 593 ? 139.186 86.639  113.166 1.00 99.73  ?  582 GLN B O   1 
ATOM   9763  C  CB  . GLN B 1 593 ? 138.857 89.877  112.990 1.00 99.73  ?  582 GLN B CB  1 
ATOM   9764  C  CG  . GLN B 1 593 ? 139.806 89.656  111.828 1.00 99.73  ?  582 GLN B CG  1 
ATOM   9765  C  CD  . GLN B 1 593 ? 140.639 90.884  111.530 1.00 99.73  ?  582 GLN B CD  1 
ATOM   9766  O  OE1 . GLN B 1 593 ? 140.702 91.813  112.335 1.00 99.73  ?  582 GLN B OE1 1 
ATOM   9767  N  NE2 . GLN B 1 593 ? 141.285 90.896  110.371 1.00 99.73  ?  582 GLN B NE2 1 
ATOM   9768  N  N   . LYS B 1 594 ? 139.074 87.610  115.186 1.00 101.96 ?  583 LYS B N   1 
ATOM   9769  C  CA  . LYS B 1 594 ? 139.821 86.538  115.830 1.00 101.96 ?  583 LYS B CA  1 
ATOM   9770  C  C   . LYS B 1 594 ? 139.007 85.267  115.773 1.00 101.96 ?  583 LYS B C   1 
ATOM   9771  O  O   . LYS B 1 594 ? 139.539 84.191  115.511 1.00 101.96 ?  583 LYS B O   1 
ATOM   9772  C  CB  . LYS B 1 594 ? 140.138 86.890  117.278 1.00 101.96 ?  583 LYS B CB  1 
ATOM   9773  C  CG  . LYS B 1 594 ? 141.622 87.038  117.566 1.00 101.96 ?  583 LYS B CG  1 
ATOM   9774  C  CD  . LYS B 1 594 ? 141.869 87.269  119.047 1.00 101.96 ?  583 LYS B CD  1 
ATOM   9775  C  CE  . LYS B 1 594 ? 143.355 87.355  119.351 1.00 101.96 ?  583 LYS B CE  1 
ATOM   9776  N  NZ  . LYS B 1 594 ? 144.066 86.103  118.974 1.00 101.96 1  583 LYS B NZ  1 
ATOM   9777  N  N   . GLN B 1 595 ? 137.709 85.387  116.012 1.00 103.28 ?  584 GLN B N   1 
ATOM   9778  C  CA  . GLN B 1 595 ? 136.835 84.231  115.938 1.00 103.28 ?  584 GLN B CA  1 
ATOM   9779  C  C   . GLN B 1 595 ? 136.743 83.744  114.504 1.00 103.28 ?  584 GLN B C   1 
ATOM   9780  O  O   . GLN B 1 595 ? 136.327 82.616  114.252 1.00 103.28 ?  584 GLN B O   1 
ATOM   9781  C  CB  . GLN B 1 595 ? 135.451 84.593  116.455 1.00 103.28 ?  584 GLN B CB  1 
ATOM   9782  C  CG  . GLN B 1 595 ? 135.445 85.118  117.878 1.00 103.28 ?  584 GLN B CG  1 
ATOM   9783  C  CD  . GLN B 1 595 ? 134.115 85.731  118.256 1.00 103.28 ?  584 GLN B CD  1 
ATOM   9784  O  OE1 . GLN B 1 595 ? 133.875 86.055  119.417 1.00 103.28 ?  584 GLN B OE1 1 
ATOM   9785  N  NE2 . GLN B 1 595 ? 133.238 85.890  117.272 1.00 103.28 ?  584 GLN B NE2 1 
ATOM   9786  N  N   . GLY B 1 596 ? 137.126 84.594  113.560 1.00 106.79 ?  585 GLY B N   1 
ATOM   9787  C  CA  . GLY B 1 596 ? 137.065 84.220  112.162 1.00 106.79 ?  585 GLY B CA  1 
ATOM   9788  C  C   . GLY B 1 596 ? 135.746 84.627  111.553 1.00 106.79 ?  585 GLY B C   1 
ATOM   9789  O  O   . GLY B 1 596 ? 135.648 84.793  110.337 1.00 106.79 ?  585 GLY B O   1 
ATOM   9790  N  N   . LEU B 1 597 ? 134.722 84.791  112.383 1.00 109.34 ?  586 LEU B N   1 
ATOM   9791  C  CA  . LEU B 1 597 ? 133.405 85.184  111.887 1.00 109.34 ?  586 LEU B CA  1 
ATOM   9792  C  C   . LEU B 1 597 ? 133.511 86.392  110.973 1.00 109.34 ?  586 LEU B C   1 
ATOM   9793  O  O   . LEU B 1 597 ? 132.562 86.729  110.268 1.00 109.34 ?  586 LEU B O   1 
ATOM   9794  C  CB  . LEU B 1 597 ? 132.454 85.488  113.043 1.00 109.34 ?  586 LEU B CB  1 
ATOM   9795  C  CG  . LEU B 1 597 ? 131.871 84.313  113.831 1.00 109.34 ?  586 LEU B CG  1 
ATOM   9796  C  CD1 . LEU B 1 597 ? 132.955 83.424  114.419 1.00 109.34 ?  586 LEU B CD1 1 
ATOM   9797  C  CD2 . LEU B 1 597 ? 130.941 84.819  114.923 1.00 109.34 ?  586 LEU B CD2 1 
ATOM   9798  N  N   . LEU B 1 598 ? 134.663 87.048  110.985 1.00 108.04 ?  587 LEU B N   1 
ATOM   9799  C  CA  . LEU B 1 598 ? 134.866 88.208  110.131 1.00 108.04 ?  587 LEU B CA  1 
ATOM   9800  C  C   . LEU B 1 598 ? 136.165 88.085  109.365 1.00 108.04 ?  587 LEU B C   1 
ATOM   9801  O  O   . LEU B 1 598 ? 137.184 87.678  109.922 1.00 108.04 ?  587 LEU B O   1 
ATOM   9802  C  CB  . LEU B 1 598 ? 134.878 89.491  110.959 1.00 108.04 ?  587 LEU B CB  1 
ATOM   9803  C  CG  . LEU B 1 598 ? 134.813 90.803  110.178 1.00 108.04 ?  587 LEU B CG  1 
ATOM   9804  C  CD1 . LEU B 1 598 ? 133.498 90.897  109.423 1.00 108.04 ?  587 LEU B CD1 1 
ATOM   9805  C  CD2 . LEU B 1 598 ? 134.971 91.985  111.120 1.00 108.04 ?  587 LEU B CD2 1 
ATOM   9806  N  N   . GLN B 1 599 ? 136.139 88.439  108.087 1.00 114.12 ?  588 GLN B N   1 
ATOM   9807  C  CA  . GLN B 1 599 ? 137.353 88.410  107.288 1.00 114.12 ?  588 GLN B CA  1 
ATOM   9808  C  C   . GLN B 1 599 ? 137.651 89.812  106.789 1.00 114.12 ?  588 GLN B C   1 
ATOM   9809  O  O   . GLN B 1 599 ? 136.792 90.688  106.852 1.00 114.12 ?  588 GLN B O   1 
ATOM   9810  C  CB  . GLN B 1 599 ? 137.212 87.445  106.113 1.00 114.12 ?  588 GLN B CB  1 
ATOM   9811  C  CG  . GLN B 1 599 ? 137.222 85.975  106.493 1.00 114.12 ?  588 GLN B CG  1 
ATOM   9812  C  CD  . GLN B 1 599 ? 135.941 85.525  107.167 1.00 114.12 ?  588 GLN B CD  1 
ATOM   9813  O  OE1 . GLN B 1 599 ? 134.953 86.258  107.208 1.00 114.12 ?  588 GLN B OE1 1 
ATOM   9814  N  NE2 . GLN B 1 599 ? 135.951 84.307  107.694 1.00 114.12 ?  588 GLN B NE2 1 
ATOM   9815  N  N   . VAL B 1 600 ? 138.859 90.032  106.288 1.00 114.63 ?  589 VAL B N   1 
ATOM   9816  C  CA  . VAL B 1 600 ? 139.233 91.371  105.848 1.00 114.63 ?  589 VAL B CA  1 
ATOM   9817  C  C   . VAL B 1 600 ? 139.493 91.450  104.350 1.00 114.63 ?  589 VAL B C   1 
ATOM   9818  O  O   . VAL B 1 600 ? 140.221 90.628  103.794 1.00 114.63 ?  589 VAL B O   1 
ATOM   9819  C  CB  . VAL B 1 600 ? 140.477 91.885  106.600 1.00 114.63 ?  589 VAL B CB  1 
ATOM   9820  C  CG1 . VAL B 1 600 ? 141.631 90.904  106.470 1.00 114.63 ?  589 VAL B CG1 1 
ATOM   9821  C  CG2 . VAL B 1 600 ? 140.870 93.258  106.088 1.00 114.63 ?  589 VAL B CG2 1 
ATOM   9822  N  N   . THR B 1 601 ? 138.892 92.434  103.692 1.00 117.04 ?  590 THR B N   1 
ATOM   9823  C  CA  . THR B 1 601 ? 139.115 92.623  102.266 1.00 117.04 ?  590 THR B CA  1 
ATOM   9824  C  C   . THR B 1 601 ? 139.409 94.084  102.006 1.00 117.04 ?  590 THR B C   1 
ATOM   9825  O  O   . THR B 1 601 ? 138.929 94.956  102.727 1.00 117.04 ?  590 THR B O   1 
ATOM   9826  C  CB  . THR B 1 601 ? 137.893 92.208  101.431 1.00 117.04 ?  590 THR B CB  1 
ATOM   9827  O  OG1 . THR B 1 601 ? 136.771 93.026  101.783 1.00 117.04 ?  590 THR B OG1 1 
ATOM   9828  C  CG2 . THR B 1 601 ? 137.548 90.753  101.681 1.00 117.04 ?  590 THR B CG2 1 
ATOM   9829  N  N   . PRO B 1 602 ? 140.197 94.366  100.964 1.00 117.23 ?  591 PRO B N   1 
ATOM   9830  C  CA  . PRO B 1 602 ? 140.459 95.762  100.619 1.00 117.23 ?  591 PRO B CA  1 
ATOM   9831  C  C   . PRO B 1 602 ? 139.151 96.422  100.246 1.00 117.23 ?  591 PRO B C   1 
ATOM   9832  O  O   . PRO B 1 602 ? 139.079 97.646  100.169 1.00 117.23 ?  591 PRO B O   1 
ATOM   9833  C  CB  . PRO B 1 602 ? 141.376 95.657  99.403  1.00 117.23 ?  591 PRO B CB  1 
ATOM   9834  C  CG  . PRO B 1 602 ? 141.989 94.300  99.496  1.00 117.23 ?  591 PRO B CG  1 
ATOM   9835  C  CD  . PRO B 1 602 ? 140.929 93.430  100.096 1.00 117.23 ?  591 PRO B CD  1 
ATOM   9836  N  N   . LYS B 1 603 ? 138.124 95.615  100.008 1.00 117.95 ?  592 LYS B N   1 
ATOM   9837  C  CA  . LYS B 1 603 ? 136.816 96.145  99.660  1.00 117.95 ?  592 LYS B CA  1 
ATOM   9838  C  C   . LYS B 1 603 ? 135.864 96.120  100.851 1.00 117.95 ?  592 LYS B C   1 
ATOM   9839  O  O   . LYS B 1 603 ? 134.674 96.384  100.696 1.00 117.95 ?  592 LYS B O   1 
ATOM   9840  C  CB  . LYS B 1 603 ? 136.228 95.343  98.503  1.00 117.95 ?  592 LYS B CB  1 
ATOM   9841  C  CG  . LYS B 1 603 ? 136.169 93.850  98.770  1.00 117.95 ?  592 LYS B CG  1 
ATOM   9842  C  CD  . LYS B 1 603 ? 135.629 93.088  97.573  1.00 117.95 ?  592 LYS B CD  1 
ATOM   9843  C  CE  . LYS B 1 603 ? 135.692 91.588  97.810  1.00 117.95 ?  592 LYS B CE  1 
ATOM   9844  N  NZ  . LYS B 1 603 ? 137.085 91.133  98.078  1.00 117.95 1  592 LYS B NZ  1 
ATOM   9845  N  N   . GLY B 1 604 ? 136.377 95.799  102.037 1.00 115.21 ?  593 GLY B N   1 
ATOM   9846  C  CA  . GLY B 1 604 ? 135.544 95.795  103.229 1.00 115.21 ?  593 GLY B CA  1 
ATOM   9847  C  C   . GLY B 1 604 ? 135.772 94.625  104.163 1.00 115.21 ?  593 GLY B C   1 
ATOM   9848  O  O   . GLY B 1 604 ? 136.876 94.087  104.236 1.00 115.21 ?  593 GLY B O   1 
ATOM   9849  N  N   . PHE B 1 605 ? 134.733 94.229  104.888 1.00 110.97 ?  594 PHE B N   1 
ATOM   9850  C  CA  . PHE B 1 605 ? 134.853 93.117  105.821 1.00 110.97 ?  594 PHE B CA  1 
ATOM   9851  C  C   . PHE B 1 605 ? 133.932 91.966  105.442 1.00 110.97 ?  594 PHE B C   1 
ATOM   9852  O  O   . PHE B 1 605 ? 132.759 92.183  105.145 1.00 110.97 ?  594 PHE B O   1 
ATOM   9853  C  CB  . PHE B 1 605 ? 134.538 93.582  107.245 1.00 110.97 ?  594 PHE B CB  1 
ATOM   9854  C  CG  . PHE B 1 605 ? 135.732 94.089  108.000 1.00 110.97 ?  594 PHE B CG  1 
ATOM   9855  C  CD1 . PHE B 1 605 ? 136.875 93.316  108.115 1.00 110.97 ?  594 PHE B CD1 1 
ATOM   9856  C  CD2 . PHE B 1 605 ? 135.703 95.327  108.617 1.00 110.97 ?  594 PHE B CD2 1 
ATOM   9857  C  CE1 . PHE B 1 605 ? 137.973 93.774  108.816 1.00 110.97 ?  594 PHE B CE1 1 
ATOM   9858  C  CE2 . PHE B 1 605 ? 136.797 95.791  109.322 1.00 110.97 ?  594 PHE B CE2 1 
ATOM   9859  C  CZ  . PHE B 1 605 ? 137.934 95.014  109.421 1.00 110.97 ?  594 PHE B CZ  1 
ATOM   9860  N  N   . ILE B 1 606 ? 134.463 90.748  105.442 1.00 114.99 ?  595 ILE B N   1 
ATOM   9861  C  CA  . ILE B 1 606 ? 133.655 89.581  105.106 1.00 114.99 ?  595 ILE B CA  1 
ATOM   9862  C  C   . ILE B 1 606 ? 132.931 89.028  106.323 1.00 114.99 ?  595 ILE B C   1 
ATOM   9863  O  O   . ILE B 1 606 ? 133.563 88.635  107.300 1.00 114.99 ?  595 ILE B O   1 
ATOM   9864  C  CB  . ILE B 1 606 ? 134.512 88.455  104.511 1.00 114.99 ?  595 ILE B CB  1 
ATOM   9865  C  CG1 . ILE B 1 606 ? 135.116 88.889  103.178 1.00 114.99 ?  595 ILE B CG1 1 
ATOM   9866  C  CG2 . ILE B 1 606 ? 133.682 87.193  104.329 1.00 114.99 ?  595 ILE B CG2 1 
ATOM   9867  C  CD1 . ILE B 1 606 ? 135.938 87.808  102.512 1.00 114.99 ?  595 ILE B CD1 1 
ATOM   9868  N  N   . CYS B 1 607 ? 131.606 88.996  106.266 1.00 116.96 ?  596 CYS B N   1 
ATOM   9869  C  CA  . CYS B 1 607 ? 130.833 88.454  107.374 1.00 116.96 ?  596 CYS B CA  1 
ATOM   9870  C  C   . CYS B 1 607 ? 130.521 86.982  107.153 1.00 116.96 ?  596 CYS B C   1 
ATOM   9871  O  O   . CYS B 1 607 ? 129.377 86.619  106.888 1.00 116.96 ?  596 CYS B O   1 
ATOM   9872  C  CB  . CYS B 1 607 ? 129.541 89.246  107.556 1.00 116.96 ?  596 CYS B CB  1 
ATOM   9873  S  SG  . CYS B 1 607 ? 129.792 91.033  107.637 1.00 116.96 ?  596 CYS B SG  1 
ATOM   9874  N  N   . THR B 1 608 ? 131.533 86.131  107.274 1.00 117.09 ?  597 THR B N   1 
ATOM   9875  C  CA  . THR B 1 608 ? 131.321 84.701  107.099 1.00 117.09 ?  597 THR B CA  1 
ATOM   9876  C  C   . THR B 1 608 ? 130.147 84.260  107.949 1.00 117.09 ?  597 THR B C   1 
ATOM   9877  O  O   . THR B 1 608 ? 129.302 83.489  107.497 1.00 117.09 ?  597 THR B O   1 
ATOM   9878  C  CB  . THR B 1 608 ? 132.571 83.899  107.485 1.00 117.09 ?  597 THR B CB  1 
ATOM   9879  O  OG1 . THR B 1 608 ? 133.566 84.058  106.468 1.00 117.09 ?  597 THR B OG1 1 
ATOM   9880  C  CG2 . THR B 1 608 ? 132.239 82.425  107.623 1.00 117.09 ?  597 THR B CG2 1 
ATOM   9881  N  N   . VAL B 1 609 ? 130.081 84.753  109.177 1.00 119.11 ?  598 VAL B N   1 
ATOM   9882  C  CA  . VAL B 1 609 ? 128.952 84.435  110.035 1.00 119.11 ?  598 VAL B CA  1 
ATOM   9883  C  C   . VAL B 1 609 ? 128.205 85.711  110.369 1.00 119.11 ?  598 VAL B C   1 
ATOM   9884  O  O   . VAL B 1 609 ? 128.789 86.648  110.912 1.00 119.11 ?  598 VAL B O   1 
ATOM   9885  C  CB  . VAL B 1 609 ? 129.405 83.763  111.337 1.00 119.11 ?  598 VAL B CB  1 
ATOM   9886  C  CG1 . VAL B 1 609 ? 128.210 83.497  112.239 1.00 119.11 ?  598 VAL B CG1 1 
ATOM   9887  C  CG2 . VAL B 1 609 ? 130.158 82.477  111.035 1.00 119.11 ?  598 VAL B CG2 1 
ATOM   9888  N  N   . ASP B 1 610 ? 126.915 85.752  110.053 1.00 121.08 ?  599 ASP B N   1 
ATOM   9889  C  CA  . ASP B 1 610 ? 126.113 86.938  110.341 1.00 121.08 ?  599 ASP B CA  1 
ATOM   9890  C  C   . ASP B 1 610 ? 125.486 86.883  111.730 1.00 121.08 ?  599 ASP B C   1 
ATOM   9891  O  O   . ASP B 1 610 ? 125.919 86.096  112.572 1.00 121.08 ?  599 ASP B O   1 
ATOM   9892  C  CB  . ASP B 1 610 ? 125.025 87.114  109.280 1.00 121.08 ?  599 ASP B CB  1 
ATOM   9893  C  CG  . ASP B 1 610 ? 125.596 87.344  107.898 1.00 121.08 ?  599 ASP B CG  1 
ATOM   9894  O  OD1 . ASP B 1 610 ? 126.834 87.297  107.753 1.00 121.08 ?  599 ASP B OD1 1 
ATOM   9895  O  OD2 . ASP B 1 610 ? 124.807 87.571  106.959 1.00 121.08 -1 599 ASP B OD2 1 
ATOM   9896  N  N   . THR B 1 611 ? 124.485 87.727  111.977 1.00 119.59 ?  600 THR B N   1 
ATOM   9897  C  CA  . THR B 1 611 ? 123.791 87.741  113.274 1.00 119.59 ?  600 THR B CA  1 
ATOM   9898  C  C   . THR B 1 611 ? 124.726 87.411  114.437 1.00 119.59 ?  600 THR B C   1 
ATOM   9899  O  O   . THR B 1 611 ? 124.487 86.465  115.188 1.00 119.59 ?  600 THR B O   1 
ATOM   9900  C  CB  . THR B 1 611 ? 122.566 86.794  113.288 1.00 119.59 ?  600 THR B CB  1 
ATOM   9901  O  OG1 . THR B 1 611 ? 121.982 86.782  114.597 1.00 119.59 ?  600 THR B OG1 1 
ATOM   9902  C  CG2 . THR B 1 611 ? 122.956 85.372  112.896 1.00 119.59 ?  600 THR B CG2 1 
ATOM   9903  N  N   . ILE B 1 612 ? 125.782 88.199  114.599 1.00 115.95 ?  601 ILE B N   1 
ATOM   9904  C  CA  . ILE B 1 612 ? 126.750 87.918  115.651 1.00 115.95 ?  601 ILE B CA  1 
ATOM   9905  C  C   . ILE B 1 612 ? 126.128 87.965  117.033 1.00 115.95 ?  601 ILE B C   1 
ATOM   9906  O  O   . ILE B 1 612 ? 125.122 88.639  117.249 1.00 115.95 ?  601 ILE B O   1 
ATOM   9907  C  CB  . ILE B 1 612 ? 127.925 88.910  115.619 1.00 115.95 ?  601 ILE B CB  1 
ATOM   9908  C  CG1 . ILE B 1 612 ? 127.403 90.347  115.687 1.00 115.95 ?  601 ILE B CG1 1 
ATOM   9909  C  CG2 . ILE B 1 612 ? 128.762 88.694  114.371 1.00 115.95 ?  601 ILE B CG2 1 
ATOM   9910  C  CD1 . ILE B 1 612 ? 128.492 91.391  115.778 1.00 115.95 ?  601 ILE B CD1 1 
ATOM   9911  N  N   . LYS B 1 613 ? 126.726 87.244  117.973 1.00 113.69 ?  602 LYS B N   1 
ATOM   9912  C  CA  . LYS B 1 613 ? 126.230 87.256  119.337 1.00 113.69 ?  602 LYS B CA  1 
ATOM   9913  C  C   . LYS B 1 613 ? 126.729 88.507  120.027 1.00 113.69 ?  602 LYS B C   1 
ATOM   9914  O  O   . LYS B 1 613 ? 127.906 88.603  120.371 1.00 113.69 ?  602 LYS B O   1 
ATOM   9915  C  CB  . LYS B 1 613 ? 126.720 86.024  120.090 1.00 113.69 ?  602 LYS B CB  1 
ATOM   9916  C  CG  . LYS B 1 613 ? 126.141 84.716  119.579 1.00 113.69 ?  602 LYS B CG  1 
ATOM   9917  C  CD  . LYS B 1 613 ? 126.692 83.532  120.359 1.00 113.69 ?  602 LYS B CD  1 
ATOM   9918  C  CE  . LYS B 1 613 ? 126.100 82.219  119.871 1.00 113.69 ?  602 LYS B CE  1 
ATOM   9919  N  NZ  . LYS B 1 613 ? 126.646 81.046  120.608 1.00 113.69 1  602 LYS B NZ  1 
ATOM   9920  N  N   . ASP B 1 614 ? 125.839 89.471  120.230 1.00 113.33 ?  603 ASP B N   1 
ATOM   9921  C  CA  . ASP B 1 614 ? 126.228 90.697  120.907 1.00 113.33 ?  603 ASP B CA  1 
ATOM   9922  C  C   . ASP B 1 614 ? 126.768 90.351  122.280 1.00 113.33 ?  603 ASP B C   1 
ATOM   9923  O  O   . ASP B 1 614 ? 126.118 89.642  123.047 1.00 113.33 ?  603 ASP B O   1 
ATOM   9924  C  CB  . ASP B 1 614 ? 125.047 91.659  121.025 1.00 113.33 ?  603 ASP B CB  1 
ATOM   9925  C  CG  . ASP B 1 614 ? 125.431 92.978  121.674 1.00 113.33 ?  603 ASP B CG  1 
ATOM   9926  O  OD1 . ASP B 1 614 ? 124.521 93.769  121.999 1.00 113.33 ?  603 ASP B OD1 1 
ATOM   9927  O  OD2 . ASP B 1 614 ? 126.641 93.224  121.863 1.00 113.33 -1 603 ASP B OD2 1 
ATOM   9928  N  N   . SER B 1 615 ? 127.960 90.843  122.592 1.00 108.25 ?  604 SER B N   1 
ATOM   9929  C  CA  . SER B 1 615 ? 128.573 90.536  123.875 1.00 108.25 ?  604 SER B CA  1 
ATOM   9930  C  C   . SER B 1 615 ? 129.432 91.692  124.355 1.00 108.25 ?  604 SER B C   1 
ATOM   9931  O  O   . SER B 1 615 ? 130.644 91.705  124.144 1.00 108.25 ?  604 SER B O   1 
ATOM   9932  C  CB  . SER B 1 615 ? 129.411 89.261  123.769 1.00 108.25 ?  604 SER B CB  1 
ATOM   9933  O  OG  . SER B 1 615 ? 130.326 89.343  122.691 1.00 108.25 ?  604 SER B OG  1 
ATOM   9934  N  N   . ASP B 1 616 ? 128.807 92.666  125.005 1.00 101.50 ?  605 ASP B N   1 
ATOM   9935  C  CA  . ASP B 1 616 ? 129.555 93.798  125.521 1.00 101.50 ?  605 ASP B CA  1 
ATOM   9936  C  C   . ASP B 1 616 ? 130.657 93.292  126.430 1.00 101.50 ?  605 ASP B C   1 
ATOM   9937  O  O   . ASP B 1 616 ? 130.420 92.435  127.278 1.00 101.50 ?  605 ASP B O   1 
ATOM   9938  C  CB  . ASP B 1 616 ? 128.633 94.753  126.268 1.00 101.50 ?  605 ASP B CB  1 
ATOM   9939  C  CG  . ASP B 1 616 ? 127.548 95.323  125.378 1.00 101.50 ?  605 ASP B CG  1 
ATOM   9940  O  OD1 . ASP B 1 616 ? 126.732 96.128  125.873 1.00 101.50 ?  605 ASP B OD1 1 
ATOM   9941  O  OD2 . ASP B 1 616 ? 127.512 94.967  124.181 1.00 101.50 -1 605 ASP B OD2 1 
ATOM   9942  N  N   . GLU B 1 617 ? 131.862 93.820  126.261 1.00 90.16  ?  606 GLU B N   1 
ATOM   9943  C  CA  . GLU B 1 617 ? 132.987 93.353  127.051 1.00 90.16  ?  606 GLU B CA  1 
ATOM   9944  C  C   . GLU B 1 617 ? 132.832 93.733  128.515 1.00 90.16  ?  606 GLU B C   1 
ATOM   9945  O  O   . GLU B 1 617 ? 133.580 93.247  129.362 1.00 90.16  ?  606 GLU B O   1 
ATOM   9946  C  CB  . GLU B 1 617 ? 134.290 93.922  126.495 1.00 90.16  ?  606 GLU B CB  1 
ATOM   9947  C  CG  . GLU B 1 617 ? 134.577 93.523  125.059 1.00 90.16  ?  606 GLU B CG  1 
ATOM   9948  C  CD  . GLU B 1 617 ? 135.871 94.115  124.538 1.00 90.16  ?  606 GLU B CD  1 
ATOM   9949  O  OE1 . GLU B 1 617 ? 136.512 94.891  125.278 1.00 90.16  ?  606 GLU B OE1 1 
ATOM   9950  O  OE2 . GLU B 1 617 ? 136.246 93.803  123.387 1.00 90.16  -1 606 GLU B OE2 1 
ATOM   9951  N  N   . GLU B 1 618 ? 131.870 94.598  128.821 1.00 86.87  ?  607 GLU B N   1 
ATOM   9952  C  CA  . GLU B 1 618 ? 131.698 95.068  130.194 1.00 86.87  ?  607 GLU B CA  1 
ATOM   9953  C  C   . GLU B 1 618 ? 133.052 95.220  130.856 1.00 86.87  ?  607 GLU B C   1 
ATOM   9954  O  O   . GLU B 1 618 ? 133.345 94.546  131.841 1.00 86.87  ?  607 GLU B O   1 
ATOM   9955  C  CB  . GLU B 1 618 ? 130.799 94.124  130.990 1.00 86.87  ?  607 GLU B CB  1 
ATOM   9956  C  CG  . GLU B 1 618 ? 129.350 94.133  130.532 1.00 86.87  ?  607 GLU B CG  1 
ATOM   9957  C  CD  . GLU B 1 618 ? 128.679 95.480  130.735 1.00 86.87  ?  607 GLU B CD  1 
ATOM   9958  O  OE1 . GLU B 1 618 ? 127.647 95.737  130.080 1.00 86.87  ?  607 GLU B OE1 1 
ATOM   9959  O  OE2 . GLU B 1 618 ? 129.182 96.285  131.547 1.00 86.87  -1 607 GLU B OE2 1 
ATOM   9960  N  N   . LEU B 1 619 ? 133.882 96.100  130.319 1.00 76.77  ?  608 LEU B N   1 
ATOM   9961  C  CA  . LEU B 1 619 ? 135.205 96.340  130.872 1.00 76.77  ?  608 LEU B CA  1 
ATOM   9962  C  C   . LEU B 1 619 ? 135.103 96.863  132.296 1.00 76.77  ?  608 LEU B C   1 
ATOM   9963  O  O   . LEU B 1 619 ? 134.246 97.686  132.622 1.00 76.77  ?  608 LEU B O   1 
ATOM   9964  C  CB  . LEU B 1 619 ? 135.971 97.341  130.014 1.00 76.77  ?  608 LEU B CB  1 
ATOM   9965  C  CG  . LEU B 1 619 ? 136.211 96.978  128.555 1.00 76.77  ?  608 LEU B CG  1 
ATOM   9966  C  CD1 . LEU B 1 619 ? 135.112 97.543  127.690 1.00 76.77  ?  608 LEU B CD1 1 
ATOM   9967  C  CD2 . LEU B 1 619 ? 137.544 97.512  128.111 1.00 76.77  ?  608 LEU B CD2 1 
ATOM   9968  N  N   . ASP B 1 620 ? 135.995 96.380  133.149 1.00 69.99  ?  609 ASP B N   1 
ATOM   9969  C  CA  . ASP B 1 620 ? 135.965 96.786  134.541 1.00 69.99  ?  609 ASP B CA  1 
ATOM   9970  C  C   . ASP B 1 620 ? 136.651 98.134  134.722 1.00 69.99  ?  609 ASP B C   1 
ATOM   9971  O  O   . ASP B 1 620 ? 137.158 98.735  133.776 1.00 69.99  ?  609 ASP B O   1 
ATOM   9972  C  CB  . ASP B 1 620 ? 136.612 95.732  135.435 1.00 69.99  ?  609 ASP B CB  1 
ATOM   9973  C  CG  . ASP B 1 620 ? 138.056 95.483  135.094 1.00 69.99  ?  609 ASP B CG  1 
ATOM   9974  O  OD1 . ASP B 1 620 ? 138.340 94.450  134.463 1.00 69.99  ?  609 ASP B OD1 1 
ATOM   9975  O  OD2 . ASP B 1 620 ? 138.910 96.310  135.463 1.00 69.99  -1 609 ASP B OD2 1 
ATOM   9976  N  N   . ASN B 1 621 ? 136.655 98.604  135.969 1.00 61.11  ?  610 ASN B N   1 
ATOM   9977  C  CA  . ASN B 1 621 ? 137.107 99.952  136.283 1.00 61.11  ?  610 ASN B CA  1 
ATOM   9978  C  C   . ASN B 1 621 ? 138.555 100.196 135.900 1.00 61.11  ?  610 ASN B C   1 
ATOM   9979  O  O   . ASN B 1 621 ? 138.927 101.343 135.640 1.00 61.11  ?  610 ASN B O   1 
ATOM   9980  C  CB  . ASN B 1 621 ? 136.919 100.220 137.774 1.00 61.11  ?  610 ASN B CB  1 
ATOM   9981  C  CG  . ASN B 1 621 ? 135.470 100.319 138.168 1.00 61.11  ?  610 ASN B CG  1 
ATOM   9982  O  OD1 . ASN B 1 621 ? 134.596 99.812  137.479 1.00 61.11  ?  610 ASN B OD1 1 
ATOM   9983  N  ND2 . ASN B 1 621 ? 135.206 100.972 139.284 1.00 61.11  ?  610 ASN B ND2 1 
ATOM   9984  N  N   . ASN B 1 622 ? 139.377 99.153  135.851 1.00 66.76  ?  611 ASN B N   1 
ATOM   9985  C  CA  . ASN B 1 622 ? 140.802 99.306  135.617 1.00 66.76  ?  611 ASN B CA  1 
ATOM   9986  C  C   . ASN B 1 622 ? 141.205 99.098  134.165 1.00 66.76  ?  611 ASN B C   1 
ATOM   9987  O  O   . ASN B 1 622 ? 142.378 99.283  133.836 1.00 66.76  ?  611 ASN B O   1 
ATOM   9988  C  CB  . ASN B 1 622 ? 141.585 98.344  136.514 1.00 66.76  ?  611 ASN B CB  1 
ATOM   9989  C  CG  . ASN B 1 622 ? 141.596 98.780  137.964 1.00 66.76  ?  611 ASN B CG  1 
ATOM   9990  O  OD1 . ASN B 1 622 ? 141.238 98.015  138.856 1.00 66.76  ?  611 ASN B OD1 1 
ATOM   9991  N  ND2 . ASN B 1 622 ? 142.012 100.015 138.207 1.00 66.76  ?  611 ASN B ND2 1 
ATOM   9992  N  N   . GLN B 1 623 ? 140.248 98.793  133.297 1.00 69.74  ?  612 GLN B N   1 
ATOM   9993  C  CA  . GLN B 1 623 ? 140.543 98.580  131.887 1.00 69.74  ?  612 GLN B CA  1 
ATOM   9994  C  C   . GLN B 1 623 ? 139.769 99.506  130.974 1.00 69.74  ?  612 GLN B C   1 
ATOM   9995  O  O   . GLN B 1 623 ? 140.005 99.517  129.773 1.00 69.74  ?  612 GLN B O   1 
ATOM   9996  C  CB  . GLN B 1 623 ? 140.202 97.145  131.511 1.00 69.74  ?  612 GLN B CB  1 
ATOM   9997  C  CG  . GLN B 1 623 ? 140.861 96.099  132.388 1.00 69.74  ?  612 GLN B CG  1 
ATOM   9998  C  CD  . GLN B 1 623 ? 140.177 94.754  132.282 1.00 69.74  ?  612 GLN B CD  1 
ATOM   9999  O  OE1 . GLN B 1 623 ? 140.701 93.739  132.739 1.00 69.74  ?  612 GLN B OE1 1 
ATOM   10000 N  NE2 . GLN B 1 623 ? 138.994 94.739  131.678 1.00 69.74  ?  612 GLN B NE2 1 
ATOM   10001 N  N   . ILE B 1 624 ? 138.851 100.289 131.522 1.00 64.44  ?  613 ILE B N   1 
ATOM   10002 C  CA  . ILE B 1 624 ? 137.995 101.136 130.690 1.00 64.44  ?  613 ILE B CA  1 
ATOM   10003 C  C   . ILE B 1 624 ? 138.728 102.272 129.976 1.00 64.44  ?  613 ILE B C   1 
ATOM   10004 O  O   . ILE B 1 624 ? 138.266 102.748 128.947 1.00 64.44  ?  613 ILE B O   1 
ATOM   10005 C  CB  . ILE B 1 624 ? 136.824 101.706 131.523 1.00 64.44  ?  613 ILE B CB  1 
ATOM   10006 C  CG1 . ILE B 1 624 ? 135.688 102.161 130.605 1.00 64.44  ?  613 ILE B CG1 1 
ATOM   10007 C  CG2 . ILE B 1 624 ? 137.299 102.838 132.421 1.00 64.44  ?  613 ILE B CG2 1 
ATOM   10008 C  CD1 . ILE B 1 624 ? 134.471 102.659 131.352 1.00 64.44  ?  613 ILE B CD1 1 
ATOM   10009 N  N   . GLU B 1 625 ? 139.868 102.699 130.499 1.00 66.19  ?  614 GLU B N   1 
ATOM   10010 C  CA  . GLU B 1 625 ? 140.584 103.829 129.908 1.00 66.19  ?  614 GLU B CA  1 
ATOM   10011 C  C   . GLU B 1 625 ? 141.132 103.527 128.517 1.00 66.19  ?  614 GLU B C   1 
ATOM   10012 O  O   . GLU B 1 625 ? 141.544 104.436 127.798 1.00 66.19  ?  614 GLU B O   1 
ATOM   10013 C  CB  . GLU B 1 625 ? 141.716 104.277 130.830 1.00 66.19  ?  614 GLU B CB  1 
ATOM   10014 C  CG  . GLU B 1 625 ? 142.345 105.605 130.438 1.00 66.19  ?  614 GLU B CG  1 
ATOM   10015 C  CD  . GLU B 1 625 ? 141.344 106.746 130.405 1.00 66.19  ?  614 GLU B CD  1 
ATOM   10016 O  OE1 . GLU B 1 625 ? 140.329 106.678 131.132 1.00 66.19  ?  614 GLU B OE1 1 
ATOM   10017 O  OE2 . GLU B 1 625 ? 141.578 107.720 129.658 1.00 66.19  -1 614 GLU B OE2 1 
ATOM   10018 N  N   . VAL B 1 626 ? 141.124 102.261 128.128 1.00 65.37  ?  615 VAL B N   1 
ATOM   10019 C  CA  . VAL B 1 626 ? 141.616 101.874 126.813 1.00 65.37  ?  615 VAL B CA  1 
ATOM   10020 C  C   . VAL B 1 626 ? 140.724 102.422 125.712 1.00 65.37  ?  615 VAL B C   1 
ATOM   10021 O  O   . VAL B 1 626 ? 141.169 102.596 124.583 1.00 65.37  ?  615 VAL B O   1 
ATOM   10022 C  CB  . VAL B 1 626 ? 141.692 100.343 126.688 1.00 65.37  ?  615 VAL B CB  1 
ATOM   10023 C  CG1 . VAL B 1 626 ? 140.296 99.740  126.644 1.00 65.37  ?  615 VAL B CG1 1 
ATOM   10024 C  CG2 . VAL B 1 626 ? 142.483 99.948  125.452 1.00 65.37  ?  615 VAL B CG2 1 
ATOM   10025 N  N   . LEU B 1 627 ? 139.472 102.709 126.036 1.00 61.82  ?  616 LEU B N   1 
ATOM   10026 C  CA  . LEU B 1 627 ? 138.530 103.200 125.043 1.00 61.82  ?  616 LEU B CA  1 
ATOM   10027 C  C   . LEU B 1 627 ? 138.685 104.690 124.789 1.00 61.82  ?  616 LEU B C   1 
ATOM   10028 O  O   . LEU B 1 627 ? 137.920 105.273 124.029 1.00 61.82  ?  616 LEU B O   1 
ATOM   10029 C  CB  . LEU B 1 627 ? 137.102 102.897 125.490 1.00 61.82  ?  616 LEU B CB  1 
ATOM   10030 C  CG  . LEU B 1 627 ? 136.736 101.430 125.687 1.00 61.82  ?  616 LEU B CG  1 
ATOM   10031 C  CD1 . LEU B 1 627 ? 135.326 101.324 126.242 1.00 61.82  ?  616 LEU B CD1 1 
ATOM   10032 C  CD2 . LEU B 1 627 ? 136.865 100.665 124.380 1.00 61.82  ?  616 LEU B CD2 1 
ATOM   10033 N  N   . ASP B 1 628 ? 139.671 105.310 125.420 1.00 63.71  ?  617 ASP B N   1 
ATOM   10034 C  CA  . ASP B 1 628 ? 139.906 106.732 125.230 1.00 63.71  ?  617 ASP B CA  1 
ATOM   10035 C  C   . ASP B 1 628 ? 141.196 106.946 124.475 1.00 63.71  ?  617 ASP B C   1 
ATOM   10036 O  O   . ASP B 1 628 ? 141.735 108.049 124.469 1.00 63.71  ?  617 ASP B O   1 
ATOM   10037 C  CB  . ASP B 1 628 ? 139.988 107.453 126.575 1.00 63.71  ?  617 ASP B CB  1 
ATOM   10038 C  CG  . ASP B 1 628 ? 138.650 107.550 127.280 1.00 63.71  ?  617 ASP B CG  1 
ATOM   10039 O  OD1 . ASP B 1 628 ? 137.603 107.325 126.640 1.00 63.71  ?  617 ASP B OD1 1 
ATOM   10040 O  OD2 . ASP B 1 628 ? 138.649 107.845 128.492 1.00 63.71  -1 617 ASP B OD2 1 
ATOM   10041 N  N   . GLN B 1 629 ? 141.699 105.904 123.829 1.00 66.65  ?  618 GLN B N   1 
ATOM   10042 C  CA  . GLN B 1 629 ? 142.988 106.001 123.150 1.00 66.65  ?  618 GLN B CA  1 
ATOM   10043 C  C   . GLN B 1 629 ? 142.882 106.198 121.645 1.00 66.65  ?  618 GLN B C   1 
ATOM   10044 O  O   . GLN B 1 629 ? 141.899 105.791 121.035 1.00 66.65  ?  618 GLN B O   1 
ATOM   10045 C  CB  . GLN B 1 629 ? 143.805 104.742 123.441 1.00 66.65  ?  618 GLN B CB  1 
ATOM   10046 C  CG  . GLN B 1 629 ? 143.994 104.454 124.918 1.00 66.65  ?  618 GLN B CG  1 
ATOM   10047 C  CD  . GLN B 1 629 ? 144.648 103.111 125.160 1.00 66.65  ?  618 GLN B CD  1 
ATOM   10048 O  OE1 . GLN B 1 629 ? 144.950 102.378 124.218 1.00 66.65  ?  618 GLN B OE1 1 
ATOM   10049 N  NE2 . GLN B 1 629 ? 144.868 102.778 126.426 1.00 66.65  ?  618 GLN B NE2 1 
ATOM   10050 N  N   . PRO B 1 630 ? 143.901 106.824 121.040 1.00 66.31  ?  619 PRO B N   1 
ATOM   10051 C  CA  . PRO B 1 630 ? 143.911 107.027 119.588 1.00 66.31  ?  619 PRO B CA  1 
ATOM   10052 C  C   . PRO B 1 630 ? 143.746 105.717 118.846 1.00 66.31  ?  619 PRO B C   1 
ATOM   10053 O  O   . PRO B 1 630 ? 144.424 104.754 119.184 1.00 66.31  ?  619 PRO B O   1 
ATOM   10054 C  CB  . PRO B 1 630 ? 145.305 107.585 119.334 1.00 66.31  ?  619 PRO B CB  1 
ATOM   10055 C  CG  . PRO B 1 630 ? 145.673 108.268 120.603 1.00 66.31  ?  619 PRO B CG  1 
ATOM   10056 C  CD  . PRO B 1 630 ? 145.062 107.445 121.698 1.00 66.31  ?  619 PRO B CD  1 
ATOM   10057 N  N   . ILE B 1 631 ? 142.856 105.677 117.863 1.00 69.49  ?  620 ILE B N   1 
ATOM   10058 C  CA  . ILE B 1 631 ? 142.590 104.449 117.133 1.00 69.49  ?  620 ILE B CA  1 
ATOM   10059 C  C   . ILE B 1 631 ? 143.643 104.203 116.071 1.00 69.49  ?  620 ILE B C   1 
ATOM   10060 O  O   . ILE B 1 631 ? 143.950 105.088 115.279 1.00 69.49  ?  620 ILE B O   1 
ATOM   10061 C  CB  . ILE B 1 631 ? 141.200 104.481 116.476 1.00 69.49  ?  620 ILE B CB  1 
ATOM   10062 C  CG1 . ILE B 1 631 ? 140.115 104.622 117.544 1.00 69.49  ?  620 ILE B CG1 1 
ATOM   10063 C  CG2 . ILE B 1 631 ? 140.972 103.232 115.643 1.00 69.49  ?  620 ILE B CG2 1 
ATOM   10064 C  CD1 . ILE B 1 631 ? 138.707 104.540 117.001 1.00 69.49  ?  620 ILE B CD1 1 
ATOM   10065 N  N   . ASN B 1 632 ? 144.202 103.000 116.056 1.00 84.48  ?  621 ASN B N   1 
ATOM   10066 C  CA  . ASN B 1 632 ? 145.215 102.659 115.077 1.00 84.48  ?  621 ASN B CA  1 
ATOM   10067 C  C   . ASN B 1 632 ? 144.797 101.403 114.348 1.00 84.48  ?  621 ASN B C   1 
ATOM   10068 O  O   . ASN B 1 632 ? 145.272 100.315 114.664 1.00 84.48  ?  621 ASN B O   1 
ATOM   10069 C  CB  . ASN B 1 632 ? 146.555 102.439 115.764 1.00 84.48  ?  621 ASN B CB  1 
ATOM   10070 C  CG  . ASN B 1 632 ? 147.694 102.278 114.782 1.00 84.48  ?  621 ASN B CG  1 
ATOM   10071 O  OD1 . ASN B 1 632 ? 147.587 102.673 113.623 1.00 84.48  ?  621 ASN B OD1 1 
ATOM   10072 N  ND2 . ASN B 1 632 ? 148.798 101.706 115.245 1.00 84.48  ?  621 ASN B ND2 1 
ATOM   10073 N  N   . THR B 1 633 ? 143.914 101.541 113.368 1.00 91.22  ?  622 THR B N   1 
ATOM   10074 C  CA  . THR B 1 633 ? 143.418 100.380 112.637 1.00 91.22  ?  622 THR B CA  1 
ATOM   10075 C  C   . THR B 1 633 ? 144.358 99.974  111.513 1.00 91.22  ?  622 THR B C   1 
ATOM   10076 O  O   . THR B 1 633 ? 143.927 99.385  110.524 1.00 91.22  ?  622 THR B O   1 
ATOM   10077 C  CB  . THR B 1 633 ? 142.027 100.645 112.034 1.00 91.22  ?  622 THR B CB  1 
ATOM   10078 O  OG1 . THR B 1 633 ? 142.071 101.835 111.238 1.00 91.22  ?  622 THR B OG1 1 
ATOM   10079 C  CG2 . THR B 1 633 ? 140.998 100.820 113.126 1.00 91.22  ?  622 THR B CG2 1 
ATOM   10080 N  N   . THR B 1 634 ? 145.642 100.283 111.660 1.00 96.13  ?  623 THR B N   1 
ATOM   10081 C  CA  . THR B 1 634 ? 146.614 99.961  110.621 1.00 96.13  ?  623 THR B CA  1 
ATOM   10082 C  C   . THR B 1 634 ? 146.701 98.465  110.387 1.00 96.13  ?  623 THR B C   1 
ATOM   10083 O  O   . THR B 1 634 ? 147.081 98.028  109.303 1.00 96.13  ?  623 THR B O   1 
ATOM   10084 C  CB  . THR B 1 634 ? 148.012 100.501 110.967 1.00 96.13  ?  623 THR B CB  1 
ATOM   10085 O  OG1 . THR B 1 634 ? 148.297 100.236 112.346 1.00 96.13  ?  623 THR B OG1 1 
ATOM   10086 C  CG2 . THR B 1 634 ? 148.075 101.997 110.719 1.00 96.13  ?  623 THR B CG2 1 
ATOM   10087 N  N   . ASP B 1 635 ? 146.349 97.674  111.392 1.00 102.00 ?  624 ASP B N   1 
ATOM   10088 C  CA  . ASP B 1 635 ? 146.344 96.234  111.213 1.00 102.00 ?  624 ASP B CA  1 
ATOM   10089 C  C   . ASP B 1 635 ? 145.543 95.929  109.972 1.00 102.00 ?  624 ASP B C   1 
ATOM   10090 O  O   . ASP B 1 635 ? 145.990 95.184  109.103 1.00 102.00 ?  624 ASP B O   1 
ATOM   10091 C  CB  . ASP B 1 635 ? 145.721 95.541  112.420 1.00 102.00 ?  624 ASP B CB  1 
ATOM   10092 C  CG  . ASP B 1 635 ? 145.648 94.039  112.255 1.00 102.00 ?  624 ASP B CG  1 
ATOM   10093 O  OD1 . ASP B 1 635 ? 146.457 93.484  111.483 1.00 102.00 ?  624 ASP B OD1 1 
ATOM   10094 O  OD2 . ASP B 1 635 ? 144.785 93.412  112.903 1.00 102.00 -1 624 ASP B OD2 1 
ATOM   10095 N  N   . LEU B 1 636 ? 144.360 96.516  109.874 1.00 102.93 ?  625 LEU B N   1 
ATOM   10096 C  CA  . LEU B 1 636 ? 143.528 96.314  108.705 1.00 102.93 ?  625 LEU B CA  1 
ATOM   10097 C  C   . LEU B 1 636 ? 144.139 97.014  107.507 1.00 102.93 ?  625 LEU B C   1 
ATOM   10098 O  O   . LEU B 1 636 ? 144.667 98.116  107.636 1.00 102.93 ?  625 LEU B O   1 
ATOM   10099 C  CB  . LEU B 1 636 ? 142.130 96.859  108.965 1.00 102.93 ?  625 LEU B CB  1 
ATOM   10100 C  CG  . LEU B 1 636 ? 141.527 96.457  110.311 1.00 102.93 ?  625 LEU B CG  1 
ATOM   10101 C  CD1 . LEU B 1 636 ? 140.238 97.216  110.576 1.00 102.93 ?  625 LEU B CD1 1 
ATOM   10102 C  CD2 . LEU B 1 636 ? 141.307 94.955  110.381 1.00 102.93 ?  625 LEU B CD2 1 
ATOM   10103 N  N   . PRO B 1 637 ? 144.074 96.377  106.330 1.00 107.70 ?  626 PRO B N   1 
ATOM   10104 C  CA  . PRO B 1 637 ? 144.612 96.985  105.107 1.00 107.70 ?  626 PRO B CA  1 
ATOM   10105 C  C   . PRO B 1 637 ? 143.885 98.259  104.704 1.00 107.70 ?  626 PRO B C   1 
ATOM   10106 O  O   . PRO B 1 637 ? 144.536 99.254  104.387 1.00 107.70 ?  626 PRO B O   1 
ATOM   10107 C  CB  . PRO B 1 637 ? 144.360 95.910  104.047 1.00 107.70 ?  626 PRO B CB  1 
ATOM   10108 C  CG  . PRO B 1 637 ? 144.259 94.632  104.810 1.00 107.70 ?  626 PRO B CG  1 
ATOM   10109 C  CD  . PRO B 1 637 ? 143.618 94.996  106.114 1.00 107.70 ?  626 PRO B CD  1 
ATOM   10110 N  N   . PHE B 1 638 ? 142.559 98.238  104.716 1.00 108.31 ?  627 PHE B N   1 
ATOM   10111 C  CA  . PHE B 1 638 ? 141.785 99.400  104.284 1.00 108.31 ?  627 PHE B CA  1 
ATOM   10112 C  C   . PHE B 1 638 ? 141.489 100.363 105.421 1.00 108.31 ?  627 PHE B C   1 
ATOM   10113 O  O   . PHE B 1 638 ? 142.048 100.238 106.509 1.00 108.31 ?  627 PHE B O   1 
ATOM   10114 C  CB  . PHE B 1 638 ? 140.471 98.938  103.658 1.00 108.31 ?  627 PHE B CB  1 
ATOM   10115 C  CG  . PHE B 1 638 ? 139.592 98.171  104.602 1.00 108.31 ?  627 PHE B CG  1 
ATOM   10116 C  CD1 . PHE B 1 638 ? 139.850 96.840  104.883 1.00 108.31 ?  627 PHE B CD1 1 
ATOM   10117 C  CD2 . PHE B 1 638 ? 138.509 98.781  105.212 1.00 108.31 ?  627 PHE B CD2 1 
ATOM   10118 C  CE1 . PHE B 1 638 ? 139.044 96.132  105.751 1.00 108.31 ?  627 PHE B CE1 1 
ATOM   10119 C  CE2 . PHE B 1 638 ? 137.699 98.079  106.081 1.00 108.31 ?  627 PHE B CE2 1 
ATOM   10120 C  CZ  . PHE B 1 638 ? 137.967 96.751  106.350 1.00 108.31 ?  627 PHE B CZ  1 
ATOM   10121 N  N   . HIS B 1 639 ? 140.608 101.325 105.170 1.00 102.84 ?  628 HIS B N   1 
ATOM   10122 C  CA  . HIS B 1 639 ? 140.239 102.289 106.198 1.00 102.84 ?  628 HIS B CA  1 
ATOM   10123 C  C   . HIS B 1 639 ? 138.762 102.165 106.533 1.00 102.84 ?  628 HIS B C   1 
ATOM   10124 O  O   . HIS B 1 639 ? 137.926 102.062 105.636 1.00 102.84 ?  628 HIS B O   1 
ATOM   10125 C  CB  . HIS B 1 639 ? 140.548 103.707 105.728 1.00 102.84 ?  628 HIS B CB  1 
ATOM   10126 C  CG  . HIS B 1 639 ? 141.989 103.931 105.395 1.00 102.84 ?  628 HIS B CG  1 
ATOM   10127 N  ND1 . HIS B 1 639 ? 142.879 104.493 106.284 1.00 102.84 ?  628 HIS B ND1 1 
ATOM   10128 C  CD2 . HIS B 1 639 ? 142.697 103.662 104.273 1.00 102.84 ?  628 HIS B CD2 1 
ATOM   10129 C  CE1 . HIS B 1 639 ? 144.072 104.565 105.723 1.00 102.84 ?  628 HIS B CE1 1 
ATOM   10130 N  NE2 . HIS B 1 639 ? 143.989 104.067 104.502 1.00 102.84 ?  628 HIS B NE2 1 
ATOM   10131 N  N   . ILE B 1 640 ? 138.434 102.178 107.820 1.00 87.93  ?  629 ILE B N   1 
ATOM   10132 C  CA  . ILE B 1 640 ? 137.044 102.056 108.232 1.00 87.93  ?  629 ILE B CA  1 
ATOM   10133 C  C   . ILE B 1 640 ? 136.335 103.395 108.212 1.00 87.93  ?  629 ILE B C   1 
ATOM   10134 O  O   . ILE B 1 640 ? 136.508 104.202 109.121 1.00 87.93  ?  629 ILE B O   1 
ATOM   10135 C  CB  . ILE B 1 640 ? 136.925 101.467 109.649 1.00 87.93  ?  629 ILE B CB  1 
ATOM   10136 C  CG1 . ILE B 1 640 ? 137.529 100.063 109.696 1.00 87.93  ?  629 ILE B CG1 1 
ATOM   10137 C  CG2 . ILE B 1 640 ? 135.473 101.439 110.097 1.00 87.93  ?  629 ILE B CG2 1 
ATOM   10138 C  CD1 . ILE B 1 640 ? 137.439 99.411  111.058 1.00 87.93  ?  629 ILE B CD1 1 
ATOM   10139 N  N   . ASP B 1 641 ? 135.549 103.649 107.174 1.00 82.05  ?  630 ASP B N   1 
ATOM   10140 C  CA  . ASP B 1 641 ? 134.768 104.872 107.138 1.00 82.05  ?  630 ASP B CA  1 
ATOM   10141 C  C   . ASP B 1 641 ? 133.839 104.817 108.322 1.00 82.05  ?  630 ASP B C   1 
ATOM   10142 O  O   . ASP B 1 641 ? 132.793 104.180 108.259 1.00 82.05  ?  630 ASP B O   1 
ATOM   10143 C  CB  . ASP B 1 641 ? 133.972 104.969 105.844 1.00 82.05  ?  630 ASP B CB  1 
ATOM   10144 C  CG  . ASP B 1 641 ? 133.144 106.242 105.760 1.00 82.05  ?  630 ASP B CG  1 
ATOM   10145 O  OD1 . ASP B 1 641 ? 132.302 106.343 104.843 1.00 82.05  ?  630 ASP B OD1 1 
ATOM   10146 O  OD2 . ASP B 1 641 ? 133.331 107.141 106.607 1.00 82.05  -1 630 ASP B OD2 1 
ATOM   10147 N  N   . TRP B 1 642 ? 134.208 105.476 109.410 1.00 71.82  ?  631 TRP B N   1 
ATOM   10148 C  CA  . TRP B 1 642 ? 133.402 105.354 110.613 1.00 71.82  ?  631 TRP B CA  1 
ATOM   10149 C  C   . TRP B 1 642 ? 132.001 105.903 110.435 1.00 71.82  ?  631 TRP B C   1 
ATOM   10150 O  O   . TRP B 1 642 ? 131.128 105.603 111.254 1.00 71.82  ?  631 TRP B O   1 
ATOM   10151 C  CB  . TRP B 1 642 ? 134.094 106.059 111.770 1.00 71.82  ?  631 TRP B CB  1 
ATOM   10152 C  CG  . TRP B 1 642 ? 135.205 105.273 112.335 1.00 71.82  ?  631 TRP B CG  1 
ATOM   10153 C  CD1 . TRP B 1 642 ? 136.523 105.571 112.279 1.00 71.82  ?  631 TRP B CD1 1 
ATOM   10154 C  CD2 . TRP B 1 642 ? 135.100 104.040 113.042 1.00 71.82  ?  631 TRP B CD2 1 
ATOM   10155 N  NE1 . TRP B 1 642 ? 137.254 104.603 112.911 1.00 71.82  ?  631 TRP B NE1 1 
ATOM   10156 C  CE2 . TRP B 1 642 ? 136.399 103.650 113.389 1.00 71.82  ?  631 TRP B CE2 1 
ATOM   10157 C  CE3 . TRP B 1 642 ? 134.031 103.229 113.417 1.00 71.82  ?  631 TRP B CE3 1 
ATOM   10158 C  CZ2 . TRP B 1 642 ? 136.660 102.486 114.092 1.00 71.82  ?  631 TRP B CZ2 1 
ATOM   10159 C  CZ3 . TRP B 1 642 ? 134.294 102.076 114.112 1.00 71.82  ?  631 TRP B CZ3 1 
ATOM   10160 C  CH2 . TRP B 1 642 ? 135.596 101.713 114.441 1.00 71.82  ?  631 TRP B CH2 1 
ATOM   10161 N  N   . ASN B 1 643 ? 131.764 106.683 109.391 1.00 74.00  ?  632 ASN B N   1 
ATOM   10162 C  CA  . ASN B 1 643 ? 130.457 107.267 109.144 1.00 74.00  ?  632 ASN B CA  1 
ATOM   10163 C  C   . ASN B 1 643 ? 129.640 106.477 108.137 1.00 74.00  ?  632 ASN B C   1 
ATOM   10164 O  O   . ASN B 1 643 ? 128.491 106.841 107.874 1.00 74.00  ?  632 ASN B O   1 
ATOM   10165 C  CB  . ASN B 1 643 ? 130.614 108.712 108.680 1.00 74.00  ?  632 ASN B CB  1 
ATOM   10166 C  CG  . ASN B 1 643 ? 131.399 109.549 109.666 1.00 74.00  ?  632 ASN B CG  1 
ATOM   10167 O  OD1 . ASN B 1 643 ? 131.184 109.471 110.871 1.00 74.00  ?  632 ASN B OD1 1 
ATOM   10168 N  ND2 . ASN B 1 643 ? 132.325 110.344 109.159 1.00 74.00  ?  632 ASN B ND2 1 
ATOM   10169 N  N   . ASP B 1 644 ? 130.197 105.417 107.572 1.00 82.61  ?  633 ASP B N   1 
ATOM   10170 C  CA  . ASP B 1 644 ? 129.423 104.473 106.787 1.00 82.61  ?  633 ASP B CA  1 
ATOM   10171 C  C   . ASP B 1 644 ? 128.972 103.334 107.702 1.00 82.61  ?  633 ASP B C   1 
ATOM   10172 O  O   . ASP B 1 644 ? 129.270 103.329 108.898 1.00 82.61  ?  633 ASP B O   1 
ATOM   10173 C  CB  . ASP B 1 644 ? 130.244 103.987 105.591 1.00 82.61  ?  633 ASP B CB  1 
ATOM   10174 C  CG  . ASP B 1 644 ? 129.380 103.680 104.386 1.00 82.61  ?  633 ASP B CG  1 
ATOM   10175 O  OD1 . ASP B 1 644 ? 129.935 103.466 103.288 1.00 82.61  ?  633 ASP B OD1 1 
ATOM   10176 O  OD2 . ASP B 1 644 ? 128.141 103.659 104.538 1.00 82.61  -1 633 ASP B OD2 1 
ATOM   10177 N  N   . ASP B 1 645 ? 128.266 102.356 107.151 1.00 89.08  ?  634 ASP B N   1 
ATOM   10178 C  CA  . ASP B 1 645 ? 127.653 101.299 107.942 1.00 89.08  ?  634 ASP B CA  1 
ATOM   10179 C  C   . ASP B 1 645 ? 128.691 100.234 108.266 1.00 89.08  ?  634 ASP B C   1 
ATOM   10180 O  O   . ASP B 1 645 ? 129.518 99.886  107.418 1.00 89.08  ?  634 ASP B O   1 
ATOM   10181 C  CB  . ASP B 1 645 ? 126.467 100.685 107.203 1.00 89.08  ?  634 ASP B CB  1 
ATOM   10182 C  CG  . ASP B 1 645 ? 125.153 101.357 107.555 1.00 89.08  ?  634 ASP B CG  1 
ATOM   10183 O  OD1 . ASP B 1 645 ? 124.393 101.711 106.629 1.00 89.08  ?  634 ASP B OD1 1 
ATOM   10184 O  OD2 . ASP B 1 645 ? 124.880 101.533 108.760 1.00 89.08  -1 634 ASP B OD2 1 
ATOM   10185 N  N   . LEU B 1 646 ? 128.679 99.758  109.509 1.00 92.26  ?  635 LEU B N   1 
ATOM   10186 C  CA  . LEU B 1 646 ? 129.683 98.794  109.947 1.00 92.26  ?  635 LEU B CA  1 
ATOM   10187 C  C   . LEU B 1 646 ? 129.181 97.361  109.900 1.00 92.26  ?  635 LEU B C   1 
ATOM   10188 O  O   . LEU B 1 646 ? 127.975 97.125  109.884 1.00 92.26  ?  635 LEU B O   1 
ATOM   10189 C  CB  . LEU B 1 646 ? 130.148 99.142  111.364 1.00 92.26  ?  635 LEU B CB  1 
ATOM   10190 C  CG  . LEU B 1 646 ? 130.887 100.465 111.544 1.00 92.26  ?  635 LEU B CG  1 
ATOM   10191 C  CD1 . LEU B 1 646 ? 131.173 100.714 113.016 1.00 92.26  ?  635 LEU B CD1 1 
ATOM   10192 C  CD2 . LEU B 1 646 ? 132.175 100.456 110.738 1.00 92.26  ?  635 LEU B CD2 1 
ATOM   10193 N  N   . PRO B 1 647 ? 130.107 96.395  109.896 1.00 98.26  ?  636 PRO B N   1 
ATOM   10194 C  CA  . PRO B 1 647 ? 129.709 94.986  109.763 1.00 98.26  ?  636 PRO B CA  1 
ATOM   10195 C  C   . PRO B 1 647 ? 128.889 94.417  110.909 1.00 98.26  ?  636 PRO B C   1 
ATOM   10196 O  O   . PRO B 1 647 ? 129.046 94.854  112.046 1.00 98.26  ?  636 PRO B O   1 
ATOM   10197 C  CB  . PRO B 1 647 ? 131.060 94.253  109.712 1.00 98.26  ?  636 PRO B CB  1 
ATOM   10198 C  CG  . PRO B 1 647 ? 132.030 95.180  110.359 1.00 98.26  ?  636 PRO B CG  1 
ATOM   10199 C  CD  . PRO B 1 647 ? 131.568 96.553  109.979 1.00 98.26  ?  636 PRO B CD  1 
ATOM   10200 N  N   . LEU B 1 648 ? 128.014 93.466  110.612 1.00 102.36 ?  637 LEU B N   1 
ATOM   10201 C  CA  . LEU B 1 648 ? 127.256 92.781  111.663 1.00 102.36 ?  637 LEU B CA  1 
ATOM   10202 C  C   . LEU B 1 648 ? 126.533 93.705  112.629 1.00 102.36 ?  637 LEU B C   1 
ATOM   10203 O  O   . LEU B 1 648 ? 126.556 93.473  113.838 1.00 102.36 ?  637 LEU B O   1 
ATOM   10204 C  CB  . LEU B 1 648 ? 128.199 91.844  112.422 1.00 102.36 ?  637 LEU B CB  1 
ATOM   10205 C  CG  . LEU B 1 648 ? 129.017 90.960  111.475 1.00 102.36 ?  637 LEU B CG  1 
ATOM   10206 C  CD1 . LEU B 1 648 ? 130.355 90.539  112.058 1.00 102.36 ?  637 LEU B CD1 1 
ATOM   10207 C  CD2 . LEU B 1 648 ? 128.215 89.768  110.979 1.00 102.36 ?  637 LEU B CD2 1 
ATOM   10208 N  N   . ASN B 1 649 ? 125.906 94.754  112.110 1.00 98.51  ?  638 ASN B N   1 
ATOM   10209 C  CA  . ASN B 1 649 ? 125.113 95.651  112.956 1.00 98.51  ?  638 ASN B CA  1 
ATOM   10210 C  C   . ASN B 1 649 ? 125.922 96.390  114.029 1.00 98.51  ?  638 ASN B C   1 
ATOM   10211 O  O   . ASN B 1 649 ? 125.342 97.003  114.925 1.00 98.51  ?  638 ASN B O   1 
ATOM   10212 C  CB  . ASN B 1 649 ? 123.965 94.870  113.605 1.00 98.51  ?  638 ASN B CB  1 
ATOM   10213 C  CG  . ASN B 1 649 ? 122.874 95.772  114.144 1.00 98.51  ?  638 ASN B CG  1 
ATOM   10214 O  OD1 . ASN B 1 649 ? 122.770 96.938  113.765 1.00 98.51  ?  638 ASN B OD1 1 
ATOM   10215 N  ND2 . ASN B 1 649 ? 122.046 95.231  115.030 1.00 98.51  ?  638 ASN B ND2 1 
ATOM   10216 N  N   . ILE B 1 650 ? 127.250 96.352  113.949 1.00 92.44  ?  639 ILE B N   1 
ATOM   10217 C  CA  . ILE B 1 650 ? 128.049 97.118  114.898 1.00 92.44  ?  639 ILE B CA  1 
ATOM   10218 C  C   . ILE B 1 650 ? 127.697 98.569  114.669 1.00 92.44  ?  639 ILE B C   1 
ATOM   10219 O  O   . ILE B 1 650 ? 127.758 99.045  113.539 1.00 92.44  ?  639 ILE B O   1 
ATOM   10220 C  CB  . ILE B 1 650 ? 129.552 96.882  114.716 1.00 92.44  ?  639 ILE B CB  1 
ATOM   10221 C  CG1 . ILE B 1 650 ? 129.878 95.404  114.933 1.00 92.44  ?  639 ILE B CG1 1 
ATOM   10222 C  CG2 . ILE B 1 650 ? 130.345 97.747  115.679 1.00 92.44  ?  639 ILE B CG2 1 
ATOM   10223 C  CD1 . ILE B 1 650 ? 131.333 95.058  114.721 1.00 92.44  ?  639 ILE B CD1 1 
ATOM   10224 N  N   . GLU B 1 651 ? 127.320 99.284  115.723 1.00 88.19  ?  640 GLU B N   1 
ATOM   10225 C  CA  . GLU B 1 651 ? 126.855 100.659 115.532 1.00 88.19  ?  640 GLU B CA  1 
ATOM   10226 C  C   . GLU B 1 651 ? 127.651 101.727 116.263 1.00 88.19  ?  640 GLU B C   1 
ATOM   10227 O  O   . GLU B 1 651 ? 128.052 101.539 117.409 1.00 88.19  ?  640 GLU B O   1 
ATOM   10228 C  CB  . GLU B 1 651 ? 125.383 100.762 115.937 1.00 88.19  ?  640 GLU B CB  1 
ATOM   10229 C  CG  . GLU B 1 651 ? 125.108 100.418 117.390 1.00 88.19  ?  640 GLU B CG  1 
ATOM   10230 C  CD  . GLU B 1 651 ? 123.646 100.577 117.753 1.00 88.19  ?  640 GLU B CD  1 
ATOM   10231 O  OE1 . GLU B 1 651 ? 123.316 100.482 118.953 1.00 88.19  ?  640 GLU B OE1 1 
ATOM   10232 O  OE2 . GLU B 1 651 ? 122.826 100.804 116.838 1.00 88.19  -1 640 GLU B OE2 1 
ATOM   10233 N  N   . VAL B 1 652 ? 127.883 102.850 115.595 1.00 76.37  ?  641 VAL B N   1 
ATOM   10234 C  CA  . VAL B 1 652 ? 128.592 103.959 116.213 1.00 76.37  ?  641 VAL B CA  1 
ATOM   10235 C  C   . VAL B 1 652 ? 127.917 105.237 115.767 1.00 76.37  ?  641 VAL B C   1 
ATOM   10236 O  O   . VAL B 1 652 ? 127.560 105.372 114.600 1.00 76.37  ?  641 VAL B O   1 
ATOM   10237 C  CB  . VAL B 1 652 ? 130.072 104.000 115.807 1.00 76.37  ?  641 VAL B CB  1 
ATOM   10238 C  CG1 . VAL B 1 652 ? 130.724 105.284 116.292 1.00 76.37  ?  641 VAL B CG1 1 
ATOM   10239 C  CG2 . VAL B 1 652 ? 130.810 102.786 116.345 1.00 76.37  ?  641 VAL B CG2 1 
ATOM   10240 N  N   . PRO B 1 653 ? 127.727 106.183 116.692 1.00 70.91  ?  642 PRO B N   1 
ATOM   10241 C  CA  . PRO B 1 653 ? 127.157 107.474 116.305 1.00 70.91  ?  642 PRO B CA  1 
ATOM   10242 C  C   . PRO B 1 653 ? 127.930 108.079 115.148 1.00 70.91  ?  642 PRO B C   1 
ATOM   10243 O  O   . PRO B 1 653 ? 129.157 108.073 115.163 1.00 70.91  ?  642 PRO B O   1 
ATOM   10244 C  CB  . PRO B 1 653 ? 127.358 108.309 117.555 1.00 70.91  ?  642 PRO B CB  1 
ATOM   10245 C  CG  . PRO B 1 653 ? 127.268 107.326 118.664 1.00 70.91  ?  642 PRO B CG  1 
ATOM   10246 C  CD  . PRO B 1 653 ? 127.903 106.069 118.147 1.00 70.91  ?  642 PRO B CD  1 
ATOM   10247 N  N   . LYS B 1 654 ? 127.224 108.587 114.148 1.00 69.70  ?  643 LYS B N   1 
ATOM   10248 C  CA  . LYS B 1 654 ? 127.883 109.166 112.983 1.00 69.70  ?  643 LYS B CA  1 
ATOM   10249 C  C   . LYS B 1 654 ? 127.880 110.677 113.053 1.00 69.70  ?  643 LYS B C   1 
ATOM   10250 O  O   . LYS B 1 654 ? 126.949 111.275 113.585 1.00 69.70  ?  643 LYS B O   1 
ATOM   10251 C  CB  . LYS B 1 654 ? 127.227 108.677 111.695 1.00 69.70  ?  643 LYS B CB  1 
ATOM   10252 C  CG  . LYS B 1 654 ? 127.383 107.181 111.482 1.00 69.70  ?  643 LYS B CG  1 
ATOM   10253 C  CD  . LYS B 1 654 ? 126.655 106.707 110.238 1.00 69.70  ?  643 LYS B CD  1 
ATOM   10254 C  CE  . LYS B 1 654 ? 126.858 105.215 110.027 1.00 69.70  ?  643 LYS B CE  1 
ATOM   10255 N  NZ  . LYS B 1 654 ? 126.309 104.752 108.723 1.00 69.70  1  643 LYS B NZ  1 
ATOM   10256 N  N   . ILE B 1 655 ? 128.920 111.298 112.525 1.00 59.67  ?  644 ILE B N   1 
ATOM   10257 C  CA  . ILE B 1 655 ? 129.050 112.744 112.593 1.00 59.67  ?  644 ILE B CA  1 
ATOM   10258 C  C   . ILE B 1 655 ? 129.357 113.269 111.202 1.00 59.67  ?  644 ILE B C   1 
ATOM   10259 O  O   . ILE B 1 655 ? 130.068 112.625 110.426 1.00 59.67  ?  644 ILE B O   1 
ATOM   10260 C  CB  . ILE B 1 655 ? 130.135 113.175 113.600 1.00 59.67  ?  644 ILE B CB  1 
ATOM   10261 C  CG1 . ILE B 1 655 ? 131.507 112.713 113.147 1.00 59.67  ?  644 ILE B CG1 1 
ATOM   10262 C  CG2 . ILE B 1 655 ? 129.848 112.606 114.969 1.00 59.67  ?  644 ILE B CG2 1 
ATOM   10263 C  CD1 . ILE B 1 655 ? 132.569 113.091 114.085 1.00 59.67  ?  644 ILE B CD1 1 
ATOM   10264 N  N   . SER B 1 656 ? 128.797 114.432 110.878 1.00 56.44  ?  645 SER B N   1 
ATOM   10265 C  CA  . SER B 1 656 ? 129.064 115.063 109.596 1.00 56.44  ?  645 SER B CA  1 
ATOM   10266 C  C   . SER B 1 656 ? 130.213 116.053 109.664 1.00 56.44  ?  645 SER B C   1 
ATOM   10267 O  O   . SER B 1 656 ? 130.693 116.496 108.620 1.00 56.44  ?  645 SER B O   1 
ATOM   10268 C  CB  . SER B 1 656 ? 127.812 115.767 109.090 1.00 56.44  ?  645 SER B CB  1 
ATOM   10269 O  OG  . SER B 1 656 ? 127.333 116.681 110.055 1.00 56.44  ?  645 SER B OG  1 
ATOM   10270 N  N   . LEU B 1 657 ? 130.664 116.396 110.862 1.00 50.48  ?  646 LEU B N   1 
ATOM   10271 C  CA  . LEU B 1 657 ? 131.734 117.364 111.023 1.00 50.48  ?  646 LEU B CA  1 
ATOM   10272 C  C   . LEU B 1 657 ? 133.061 116.777 110.577 1.00 50.48  ?  646 LEU B C   1 
ATOM   10273 O  O   . LEU B 1 657 ? 133.439 115.686 111.004 1.00 50.48  ?  646 LEU B O   1 
ATOM   10274 C  CB  . LEU B 1 657 ? 131.819 117.795 112.480 1.00 50.48  ?  646 LEU B CB  1 
ATOM   10275 C  CG  . LEU B 1 657 ? 132.769 118.935 112.801 1.00 50.48  ?  646 LEU B CG  1 
ATOM   10276 C  CD1 . LEU B 1 657 ? 132.200 120.195 112.251 1.00 50.48  ?  646 LEU B CD1 1 
ATOM   10277 C  CD2 . LEU B 1 657 ? 132.975 119.048 114.285 1.00 50.48  ?  646 LEU B CD2 1 
ATOM   10278 N  N   . HIS B 1 658 ? 133.779 117.503 109.729 1.00 50.17  ?  647 HIS B N   1 
ATOM   10279 C  CA  . HIS B 1 658 ? 135.147 117.140 109.419 1.00 50.17  ?  647 HIS B CA  1 
ATOM   10280 C  C   . HIS B 1 658 ? 136.136 118.256 109.703 1.00 50.17  ?  647 HIS B C   1 
ATOM   10281 O  O   . HIS B 1 658 ? 137.340 118.000 109.698 1.00 50.17  ?  647 HIS B O   1 
ATOM   10282 C  CB  . HIS B 1 658 ? 135.285 116.683 107.956 1.00 50.17  ?  647 HIS B CB  1 
ATOM   10283 C  CG  . HIS B 1 658 ? 134.861 117.698 106.943 1.00 50.17  ?  647 HIS B CG  1 
ATOM   10284 N  ND1 . HIS B 1 658 ? 135.593 118.830 106.670 1.00 50.17  ?  647 HIS B ND1 1 
ATOM   10285 C  CD2 . HIS B 1 658 ? 133.798 117.729 106.109 1.00 50.17  ?  647 HIS B CD2 1 
ATOM   10286 C  CE1 . HIS B 1 658 ? 134.988 119.527 105.729 1.00 50.17  ?  647 HIS B CE1 1 
ATOM   10287 N  NE2 . HIS B 1 658 ? 133.897 118.879 105.369 1.00 50.17  ?  647 HIS B NE2 1 
ATOM   10288 N  N   . SER B 1 659 ? 135.671 119.470 109.967 1.00 47.25  ?  648 SER B N   1 
ATOM   10289 C  CA  . SER B 1 659 ? 136.560 120.594 110.213 1.00 47.25  ?  648 SER B CA  1 
ATOM   10290 C  C   . SER B 1 659 ? 135.933 121.507 111.246 1.00 47.25  ?  648 SER B C   1 
ATOM   10291 O  O   . SER B 1 659 ? 134.753 121.839 111.144 1.00 47.25  ?  648 SER B O   1 
ATOM   10292 C  CB  . SER B 1 659 ? 136.838 121.373 108.931 1.00 47.25  ?  648 SER B CB  1 
ATOM   10293 O  OG  . SER B 1 659 ? 137.512 120.576 107.986 1.00 47.25  ?  648 SER B OG  1 
ATOM   10294 N  N   . LEU B 1 660 ? 136.720 121.908 112.231 1.00 42.61  ?  649 LEU B N   1 
ATOM   10295 C  CA  . LEU B 1 660 ? 136.278 122.827 113.266 1.00 42.61  ?  649 LEU B CA  1 
ATOM   10296 C  C   . LEU B 1 660 ? 137.214 124.022 113.273 1.00 42.61  ?  649 LEU B C   1 
ATOM   10297 O  O   . LEU B 1 660 ? 138.427 123.861 113.405 1.00 42.61  ?  649 LEU B O   1 
ATOM   10298 C  CB  . LEU B 1 660 ? 136.250 122.140 114.629 1.00 42.61  ?  649 LEU B CB  1 
ATOM   10299 C  CG  . LEU B 1 660 ? 136.031 123.011 115.859 1.00 42.61  ?  649 LEU B CG  1 
ATOM   10300 C  CD1 . LEU B 1 660 ? 134.629 123.557 115.892 1.00 42.61  ?  649 LEU B CD1 1 
ATOM   10301 C  CD2 . LEU B 1 660 ? 136.328 122.219 117.101 1.00 42.61  ?  649 LEU B CD2 1 
ATOM   10302 N  N   . ILE B 1 661 ? 136.653 125.212 113.112 1.00 39.26  ?  650 ILE B N   1 
ATOM   10303 C  CA  . ILE B 1 661 ? 137.412 126.451 113.150 1.00 39.26  ?  650 ILE B CA  1 
ATOM   10304 C  C   . ILE B 1 661 ? 137.090 127.156 114.454 1.00 39.26  ?  650 ILE B C   1 
ATOM   10305 O  O   . ILE B 1 661 ? 135.920 127.370 114.778 1.00 39.26  ?  650 ILE B O   1 
ATOM   10306 C  CB  . ILE B 1 661 ? 137.093 127.346 111.945 1.00 39.26  ?  650 ILE B CB  1 
ATOM   10307 C  CG1 . ILE B 1 661 ? 137.412 126.618 110.645 1.00 39.26  ?  650 ILE B CG1 1 
ATOM   10308 C  CG2 . ILE B 1 661 ? 137.860 128.639 112.030 1.00 39.26  ?  650 ILE B CG2 1 
ATOM   10309 C  CD1 . ILE B 1 661 ? 136.950 127.340 109.437 1.00 39.26  ?  650 ILE B CD1 1 
ATOM   10310 N  N   . LEU B 1 662 ? 138.120 127.502 115.208 1.00 40.17  ?  651 LEU B N   1 
ATOM   10311 C  CA  . LEU B 1 662 ? 137.972 128.247 116.449 1.00 40.17  ?  651 LEU B CA  1 
ATOM   10312 C  C   . LEU B 1 662 ? 138.418 129.678 116.200 1.00 40.17  ?  651 LEU B C   1 
ATOM   10313 O  O   . LEU B 1 662 ? 139.600 129.935 115.974 1.00 40.17  ?  651 LEU B O   1 
ATOM   10314 C  CB  . LEU B 1 662 ? 138.781 127.605 117.570 1.00 40.17  ?  651 LEU B CB  1 
ATOM   10315 C  CG  . LEU B 1 662 ? 138.352 126.202 117.990 1.00 40.17  ?  651 LEU B CG  1 
ATOM   10316 C  CD1 . LEU B 1 662 ? 139.239 125.696 119.093 1.00 40.17  ?  651 LEU B CD1 1 
ATOM   10317 C  CD2 . LEU B 1 662 ? 136.908 126.187 118.423 1.00 40.17  ?  651 LEU B CD2 1 
ATOM   10318 N  N   . ASP B 1 663 ? 137.470 130.604 116.235 1.00 44.14  ?  652 ASP B N   1 
ATOM   10319 C  CA  . ASP B 1 663 ? 137.756 132.022 116.056 1.00 44.14  ?  652 ASP B CA  1 
ATOM   10320 C  C   . ASP B 1 663 ? 138.260 132.581 117.377 1.00 44.14  ?  652 ASP B C   1 
ATOM   10321 O  O   . ASP B 1 663 ? 137.486 132.814 118.304 1.00 44.14  ?  652 ASP B O   1 
ATOM   10322 C  CB  . ASP B 1 663 ? 136.514 132.757 115.574 1.00 44.14  ?  652 ASP B CB  1 
ATOM   10323 C  CG  . ASP B 1 663 ? 136.716 134.245 115.498 1.00 44.14  ?  652 ASP B CG  1 
ATOM   10324 O  OD1 . ASP B 1 663 ? 137.809 134.679 115.092 1.00 44.14  ?  652 ASP B OD1 1 
ATOM   10325 O  OD2 . ASP B 1 663 ? 135.780 134.988 115.837 1.00 44.14  -1 652 ASP B OD2 1 
ATOM   10326 N  N   . PHE B 1 664 ? 139.569 132.802 117.466 1.00 42.68  ?  653 PHE B N   1 
ATOM   10327 C  CA  . PHE B 1 664 ? 140.218 133.204 118.704 1.00 42.68  ?  653 PHE B CA  1 
ATOM   10328 C  C   . PHE B 1 664 ? 140.656 134.662 118.687 1.00 42.68  ?  653 PHE B C   1 
ATOM   10329 O  O   . PHE B 1 664 ? 141.616 135.023 119.367 1.00 42.68  ?  653 PHE B O   1 
ATOM   10330 C  CB  . PHE B 1 664 ? 141.419 132.304 118.979 1.00 42.68  ?  653 PHE B CB  1 
ATOM   10331 C  CG  . PHE B 1 664 ? 141.125 131.147 119.875 1.00 42.68  ?  653 PHE B CG  1 
ATOM   10332 C  CD1 . PHE B 1 664 ? 139.872 130.583 119.914 1.00 42.68  ?  653 PHE B CD1 1 
ATOM   10333 C  CD2 . PHE B 1 664 ? 142.108 130.623 120.681 1.00 42.68  ?  653 PHE B CD2 1 
ATOM   10334 C  CE1 . PHE B 1 664 ? 139.609 129.523 120.734 1.00 42.68  ?  653 PHE B CE1 1 
ATOM   10335 C  CE2 . PHE B 1 664 ? 141.846 129.564 121.504 1.00 42.68  ?  653 PHE B CE2 1 
ATOM   10336 C  CZ  . PHE B 1 664 ? 140.596 129.015 121.528 1.00 42.68  ?  653 PHE B CZ  1 
ATOM   10337 N  N   . SER B 1 665 ? 139.971 135.510 117.925 1.00 44.90  ?  654 SER B N   1 
ATOM   10338 C  CA  . SER B 1 665 ? 140.401 136.898 117.811 1.00 44.90  ?  654 SER B CA  1 
ATOM   10339 C  C   . SER B 1 665 ? 140.188 137.661 119.109 1.00 44.90  ?  654 SER B C   1 
ATOM   10340 O  O   . SER B 1 665 ? 141.012 138.501 119.479 1.00 44.90  ?  654 SER B O   1 
ATOM   10341 C  CB  . SER B 1 665 ? 139.671 137.584 116.665 1.00 44.90  ?  654 SER B CB  1 
ATOM   10342 O  OG  . SER B 1 665 ? 138.345 137.126 116.573 1.00 44.90  ?  654 SER B OG  1 
ATOM   10343 N  N   . ALA B 1 666 ? 139.098 137.385 119.812 1.00 45.03  ?  655 ALA B N   1 
ATOM   10344 C  CA  . ALA B 1 666 ? 138.787 138.067 121.056 1.00 45.03  ?  655 ALA B CA  1 
ATOM   10345 C  C   . ALA B 1 666 ? 139.323 137.347 122.281 1.00 45.03  ?  655 ALA B C   1 
ATOM   10346 O  O   . ALA B 1 666 ? 139.110 137.820 123.396 1.00 45.03  ?  655 ALA B O   1 
ATOM   10347 C  CB  . ALA B 1 666 ? 137.277 138.253 121.191 1.00 45.03  ?  655 ALA B CB  1 
ATOM   10348 N  N   . VAL B 1 667 ? 140.009 136.221 122.105 1.00 45.79  ?  656 VAL B N   1 
ATOM   10349 C  CA  . VAL B 1 667 ? 140.626 135.499 123.213 1.00 45.79  ?  656 VAL B CA  1 
ATOM   10350 C  C   . VAL B 1 667 ? 141.937 136.209 123.530 1.00 45.79  ?  656 VAL B C   1 
ATOM   10351 O  O   . VAL B 1 667 ? 142.958 135.962 122.896 1.00 45.79  ?  656 VAL B O   1 
ATOM   10352 C  CB  . VAL B 1 667 ? 140.841 134.022 122.883 1.00 45.79  ?  656 VAL B CB  1 
ATOM   10353 C  CG1 . VAL B 1 667 ? 141.483 133.308 124.046 1.00 45.79  ?  656 VAL B CG1 1 
ATOM   10354 C  CG2 . VAL B 1 667 ? 139.524 133.374 122.528 1.00 45.79  ?  656 VAL B CG2 1 
ATOM   10355 N  N   . SER B 1 668 ? 141.890 137.169 124.429 1.00 47.00  ?  657 SER B N   1 
ATOM   10356 C  CA  . SER B 1 668 ? 143.067 137.957 124.747 1.00 47.00  ?  657 SER B CA  1 
ATOM   10357 C  C   . SER B 1 668 ? 144.248 137.163 125.281 1.00 47.00  ?  657 SER B C   1 
ATOM   10358 O  O   . SER B 1 668 ? 145.362 137.309 124.818 1.00 47.00  ?  657 SER B O   1 
ATOM   10359 C  CB  . SER B 1 668 ? 142.689 139.069 125.715 1.00 47.00  ?  657 SER B CB  1 
ATOM   10360 O  OG  . SER B 1 668 ? 141.601 139.795 125.199 1.00 47.00  ?  657 SER B OG  1 
ATOM   10361 N  N   . PHE B 1 669 ? 143.989 136.328 126.267 1.00 45.38  ?  658 PHE B N   1 
ATOM   10362 C  CA  . PHE B 1 669 ? 145.017 135.536 126.894 1.00 45.38  ?  658 PHE B CA  1 
ATOM   10363 C  C   . PHE B 1 669 ? 144.488 134.171 127.242 1.00 45.38  ?  658 PHE B C   1 
ATOM   10364 O  O   . PHE B 1 669 ? 143.309 133.924 127.168 1.00 45.38  ?  658 PHE B O   1 
ATOM   10365 C  CB  . PHE B 1 669 ? 145.551 136.232 128.162 1.00 45.38  ?  658 PHE B CB  1 
ATOM   10366 C  CG  . PHE B 1 669 ? 144.539 136.366 129.266 1.00 45.38  ?  658 PHE B CG  1 
ATOM   10367 C  CD1 . PHE B 1 669 ? 144.330 135.331 130.158 1.00 45.38  ?  658 PHE B CD1 1 
ATOM   10368 C  CD2 . PHE B 1 669 ? 143.807 137.526 129.416 1.00 45.38  ?  658 PHE B CD2 1 
ATOM   10369 C  CE1 . PHE B 1 669 ? 143.400 135.445 131.160 1.00 45.38  ?  658 PHE B CE1 1 
ATOM   10370 C  CE2 . PHE B 1 669 ? 142.879 137.649 130.425 1.00 45.38  ?  658 PHE B CE2 1 
ATOM   10371 C  CZ  . PHE B 1 669 ? 142.676 136.607 131.301 1.00 45.38  ?  658 PHE B CZ  1 
ATOM   10372 N  N   . LEU B 1 670 ? 145.407 133.282 127.570 1.00 47.68  ?  659 LEU B N   1 
ATOM   10373 C  CA  . LEU B 1 670 ? 145.124 131.935 128.026 1.00 47.68  ?  659 LEU B CA  1 
ATOM   10374 C  C   . LEU B 1 670 ? 145.928 131.724 129.314 1.00 47.68  ?  659 LEU B C   1 
ATOM   10375 O  O   . LEU B 1 670 ? 146.904 132.406 129.541 1.00 47.68  ?  659 LEU B O   1 
ATOM   10376 C  CB  . LEU B 1 670 ? 145.529 130.906 126.975 1.00 47.68  ?  659 LEU B CB  1 
ATOM   10377 C  CG  . LEU B 1 670 ? 144.773 130.797 125.655 1.00 47.68  ?  659 LEU B CG  1 
ATOM   10378 C  CD1 . LEU B 1 670 ? 145.451 129.806 124.736 1.00 47.68  ?  659 LEU B CD1 1 
ATOM   10379 C  CD2 . LEU B 1 670 ? 143.314 130.429 125.841 1.00 47.68  ?  659 LEU B CD2 1 
ATOM   10380 N  N   . ASP B 1 671 ? 145.503 130.818 130.170 1.00 44.51  ?  660 ASP B N   1 
ATOM   10381 C  CA  . ASP B 1 671 ? 146.290 130.509 131.360 1.00 44.51  ?  660 ASP B CA  1 
ATOM   10382 C  C   . ASP B 1 671 ? 146.604 129.010 131.373 1.00 44.51  ?  660 ASP B C   1 
ATOM   10383 O  O   . ASP B 1 671 ? 146.248 128.317 130.444 1.00 44.51  ?  660 ASP B O   1 
ATOM   10384 C  CB  . ASP B 1 671 ? 145.651 131.054 132.644 1.00 44.51  ?  660 ASP B CB  1 
ATOM   10385 C  CG  . ASP B 1 671 ? 144.462 130.252 133.122 1.00 44.51  ?  660 ASP B CG  1 
ATOM   10386 O  OD1 . ASP B 1 671 ? 144.236 130.242 134.337 1.00 44.51  ?  660 ASP B OD1 1 
ATOM   10387 O  OD2 . ASP B 1 671 ? 143.748 129.639 132.317 1.00 44.51  -1 660 ASP B OD2 1 
ATOM   10388 N  N   . VAL B 1 672 ? 147.282 128.488 132.382 1.00 45.25  ?  661 VAL B N   1 
ATOM   10389 C  CA  . VAL B 1 672 ? 147.588 127.060 132.337 1.00 45.25  ?  661 VAL B CA  1 
ATOM   10390 C  C   . VAL B 1 672 ? 146.351 126.170 132.325 1.00 45.25  ?  661 VAL B C   1 
ATOM   10391 O  O   . VAL B 1 672 ? 146.337 125.163 131.642 1.00 45.25  ?  661 VAL B O   1 
ATOM   10392 C  CB  . VAL B 1 672 ? 148.588 126.584 133.416 1.00 45.25  ?  661 VAL B CB  1 
ATOM   10393 C  CG1 . VAL B 1 672 ? 149.954 127.191 133.194 1.00 45.25  ?  661 VAL B CG1 1 
ATOM   10394 C  CG2 . VAL B 1 672 ? 148.073 126.871 134.806 1.00 45.25  ?  661 VAL B CG2 1 
ATOM   10395 N  N   . SER B 1 673 ? 145.332 126.521 133.095 1.00 45.50  ?  662 SER B N   1 
ATOM   10396 C  CA  . SER B 1 673 ? 144.123 125.725 133.107 1.00 45.50  ?  662 SER B CA  1 
ATOM   10397 C  C   . SER B 1 673 ? 143.459 125.734 131.750 1.00 45.50  ?  662 SER B C   1 
ATOM   10398 O  O   . SER B 1 673 ? 142.992 124.713 131.285 1.00 45.50  ?  662 SER B O   1 
ATOM   10399 C  CB  . SER B 1 673 ? 143.122 126.257 134.127 1.00 45.50  ?  662 SER B CB  1 
ATOM   10400 O  OG  . SER B 1 673 ? 143.747 126.601 135.339 1.00 45.50  ?  662 SER B OG  1 
ATOM   10401 N  N   . SER B 1 674 ? 143.379 126.899 131.130 1.00 43.51  ?  663 SER B N   1 
ATOM   10402 C  CA  . SER B 1 674 ? 142.755 126.975 129.827 1.00 43.51  ?  663 SER B CA  1 
ATOM   10403 C  C   . SER B 1 674 ? 143.531 126.224 128.764 1.00 43.51  ?  663 SER B C   1 
ATOM   10404 O  O   . SER B 1 674 ? 142.930 125.574 127.968 1.00 43.51  ?  663 SER B O   1 
ATOM   10405 C  CB  . SER B 1 674 ? 142.413 128.404 129.406 1.00 43.51  ?  663 SER B CB  1 
ATOM   10406 O  OG  . SER B 1 674 ? 143.543 129.233 129.352 1.00 43.51  ?  663 SER B OG  1 
ATOM   10407 N  N   . VAL B 1 675 ? 144.854 126.314 128.761 1.00 47.95  ?  664 VAL B N   1 
ATOM   10408 C  CA  . VAL B 1 675 ? 145.678 125.621 127.778 1.00 47.95  ?  664 VAL B CA  1 
ATOM   10409 C  C   . VAL B 1 675 ? 145.538 124.112 127.908 1.00 47.95  ?  664 VAL B C   1 
ATOM   10410 O  O   . VAL B 1 675 ? 145.489 123.407 126.917 1.00 47.95  ?  664 VAL B O   1 
ATOM   10411 C  CB  . VAL B 1 675 ? 147.157 126.048 127.868 1.00 47.95  ?  664 VAL B CB  1 
ATOM   10412 C  CG1 . VAL B 1 675 ? 148.031 125.203 126.963 1.00 47.95  ?  664 VAL B CG1 1 
ATOM   10413 C  CG2 . VAL B 1 675 ? 147.302 127.511 127.513 1.00 47.95  ?  664 VAL B CG2 1 
ATOM   10414 N  N   . ARG B 1 676 ? 145.498 123.621 129.137 1.00 47.56  ?  665 ARG B N   1 
ATOM   10415 C  CA  . ARG B 1 676 ? 145.326 122.206 129.386 1.00 47.56  ?  665 ARG B CA  1 
ATOM   10416 C  C   . ARG B 1 676 ? 143.976 121.742 128.898 1.00 47.56  ?  665 ARG B C   1 
ATOM   10417 O  O   . ARG B 1 676 ? 143.858 120.677 128.329 1.00 47.56  ?  665 ARG B O   1 
ATOM   10418 C  CB  . ARG B 1 676 ? 145.467 121.891 130.868 1.00 47.56  ?  665 ARG B CB  1 
ATOM   10419 C  CG  . ARG B 1 676 ? 146.900 121.728 131.319 1.00 47.56  ?  665 ARG B CG  1 
ATOM   10420 C  CD  . ARG B 1 676 ? 147.020 121.719 132.830 1.00 47.56  ?  665 ARG B CD  1 
ATOM   10421 N  NE  . ARG B 1 676 ? 148.395 121.943 133.267 1.00 47.56  ?  665 ARG B NE  1 
ATOM   10422 C  CZ  . ARG B 1 676 ? 148.753 122.135 134.531 1.00 47.56  ?  665 ARG B CZ  1 
ATOM   10423 N  NH1 . ARG B 1 676 ? 147.837 122.136 135.485 1.00 47.56  1  665 ARG B NH1 1 
ATOM   10424 N  NH2 . ARG B 1 676 ? 150.025 122.329 134.842 1.00 47.56  ?  665 ARG B NH2 1 
ATOM   10425 N  N   . GLY B 1 677 ? 142.959 122.555 129.146 1.00 46.93  ?  666 GLY B N   1 
ATOM   10426 C  CA  . GLY B 1 677 ? 141.607 122.263 128.748 1.00 46.93  ?  666 GLY B CA  1 
ATOM   10427 C  C   . GLY B 1 677 ? 141.508 122.386 127.261 1.00 46.93  ?  666 GLY B C   1 
ATOM   10428 O  O   . GLY B 1 677 ? 140.815 121.625 126.629 1.00 46.93  ?  666 GLY B O   1 
ATOM   10429 N  N   . LEU B 1 678 ? 142.166 123.388 126.704 1.00 48.42  ?  667 LEU B N   1 
ATOM   10430 C  CA  . LEU B 1 678 ? 142.186 123.529 125.262 1.00 48.42  ?  667 LEU B CA  1 
ATOM   10431 C  C   . LEU B 1 678 ? 142.886 122.355 124.589 1.00 48.42  ?  667 LEU B C   1 
ATOM   10432 O  O   . LEU B 1 678 ? 142.402 121.834 123.596 1.00 48.42  ?  667 LEU B O   1 
ATOM   10433 C  CB  . LEU B 1 678 ? 142.847 124.844 124.863 1.00 48.42  ?  667 LEU B CB  1 
ATOM   10434 C  CG  . LEU B 1 678 ? 142.896 125.133 123.362 1.00 48.42  ?  667 LEU B CG  1 
ATOM   10435 C  CD1 . LEU B 1 678 ? 141.496 125.141 122.769 1.00 48.42  ?  667 LEU B CD1 1 
ATOM   10436 C  CD2 . LEU B 1 678 ? 143.606 126.450 123.094 1.00 48.42  ?  667 LEU B CD2 1 
ATOM   10437 N  N   . LYS B 1 679 ? 143.992 121.921 125.126 1.00 48.82  ?  668 LYS B N   1 
ATOM   10438 C  CA  . LYS B 1 679 ? 144.751 120.841 124.522 1.00 48.82  ?  668 LYS B CA  1 
ATOM   10439 C  C   . LYS B 1 679 ? 143.948 119.555 124.547 1.00 48.82  ?  668 LYS B C   1 
ATOM   10440 O  O   . LYS B 1 679 ? 143.898 118.837 123.555 1.00 48.82  ?  668 LYS B O   1 
ATOM   10441 C  CB  . LYS B 1 679 ? 146.090 120.649 125.229 1.00 48.82  ?  668 LYS B CB  1 
ATOM   10442 C  CG  . LYS B 1 679 ? 147.010 119.699 124.485 1.00 48.82  ?  668 LYS B CG  1 
ATOM   10443 C  CD  . LYS B 1 679 ? 148.429 119.745 125.016 1.00 48.82  ?  668 LYS B CD  1 
ATOM   10444 C  CE  . LYS B 1 679 ? 149.332 118.835 124.204 1.00 48.82  ?  668 LYS B CE  1 
ATOM   10445 N  NZ  . LYS B 1 679 ? 150.738 118.882 124.686 1.00 48.82  1  668 LYS B NZ  1 
ATOM   10446 N  N   . SER B 1 680 ? 143.291 119.287 125.669 1.00 49.16  ?  669 SER B N   1 
ATOM   10447 C  CA  . SER B 1 680 ? 142.454 118.108 125.796 1.00 49.16  ?  669 SER B CA  1 
ATOM   10448 C  C   . SER B 1 680 ? 141.379 118.118 124.730 1.00 49.16  ?  669 SER B C   1 
ATOM   10449 O  O   . SER B 1 680 ? 141.163 117.123 124.061 1.00 49.16  ?  669 SER B O   1 
ATOM   10450 C  CB  . SER B 1 680 ? 141.782 118.064 127.159 1.00 49.16  ?  669 SER B CB  1 
ATOM   10451 O  OG  . SER B 1 680 ? 142.722 117.842 128.174 1.00 49.16  ?  669 SER B OG  1 
ATOM   10452 N  N   . ILE B 1 681 ? 140.696 119.245 124.584 1.00 49.73  ?  670 ILE B N   1 
ATOM   10453 C  CA  . ILE B 1 681 ? 139.642 119.365 123.586 1.00 49.73  ?  670 ILE B CA  1 
ATOM   10454 C  C   . ILE B 1 681 ? 140.174 119.086 122.198 1.00 49.73  ?  670 ILE B C   1 
ATOM   10455 O  O   . ILE B 1 681 ? 139.618 118.283 121.462 1.00 49.73  ?  670 ILE B O   1 
ATOM   10456 C  CB  . ILE B 1 681 ? 139.049 120.789 123.550 1.00 49.73  ?  670 ILE B CB  1 
ATOM   10457 C  CG1 . ILE B 1 681 ? 138.497 121.194 124.910 1.00 49.73  ?  670 ILE B CG1 1 
ATOM   10458 C  CG2 . ILE B 1 681 ? 137.961 120.888 122.491 1.00 49.73  ?  670 ILE B CG2 1 
ATOM   10459 C  CD1 . ILE B 1 681 ? 138.218 122.677 124.999 1.00 49.73  ?  670 ILE B CD1 1 
ATOM   10460 N  N   . LEU B 1 682 ? 141.261 119.745 121.839 1.00 51.38  ?  671 LEU B N   1 
ATOM   10461 C  CA  . LEU B 1 682 ? 141.829 119.576 120.515 1.00 51.38  ?  671 LEU B CA  1 
ATOM   10462 C  C   . LEU B 1 682 ? 142.287 118.151 120.266 1.00 51.38  ?  671 LEU B C   1 
ATOM   10463 O  O   . LEU B 1 682 ? 142.054 117.610 119.194 1.00 51.38  ?  671 LEU B O   1 
ATOM   10464 C  CB  . LEU B 1 682 ? 142.991 120.548 120.321 1.00 51.38  ?  671 LEU B CB  1 
ATOM   10465 C  CG  . LEU B 1 682 ? 142.646 122.027 120.485 1.00 51.38  ?  671 LEU B CG  1 
ATOM   10466 C  CD1 . LEU B 1 682 ? 143.763 122.892 119.929 1.00 51.38  ?  671 LEU B CD1 1 
ATOM   10467 C  CD2 . LEU B 1 682 ? 141.332 122.346 119.793 1.00 51.38  ?  671 LEU B CD2 1 
ATOM   10468 N  N   . GLN B 1 683 ? 142.918 117.536 121.257 1.00 53.32  ?  672 GLN B N   1 
ATOM   10469 C  CA  . GLN B 1 683 ? 143.402 116.171 121.101 1.00 53.32  ?  672 GLN B CA  1 
ATOM   10470 C  C   . GLN B 1 683 ? 142.254 115.226 120.798 1.00 53.32  ?  672 GLN B C   1 
ATOM   10471 O  O   . GLN B 1 683 ? 142.375 114.367 119.936 1.00 53.32  ?  672 GLN B O   1 
ATOM   10472 C  CB  . GLN B 1 683 ? 144.160 115.708 122.347 1.00 53.32  ?  672 GLN B CB  1 
ATOM   10473 C  CG  . GLN B 1 683 ? 145.546 116.305 122.493 1.00 53.32  ?  672 GLN B CG  1 
ATOM   10474 C  CD  . GLN B 1 683 ? 146.141 116.047 123.861 1.00 53.32  ?  672 GLN B CD  1 
ATOM   10475 O  OE1 . GLN B 1 683 ? 145.302 116.083 124.888 1.00 53.32  ?  672 GLN B OE1 1 
ATOM   10476 N  NE2 . GLN B 1 683 ? 147.339 115.809 123.993 1.00 53.32  ?  672 GLN B NE2 1 
ATOM   10477 N  N   . GLU B 1 684 ? 141.145 115.402 121.497 1.00 50.67  ?  673 GLU B N   1 
ATOM   10478 C  CA  . GLU B 1 684 ? 139.968 114.579 121.304 1.00 50.67  ?  673 GLU B CA  1 
ATOM   10479 C  C   . GLU B 1 684 ? 139.363 114.752 119.924 1.00 50.67  ?  673 GLU B C   1 
ATOM   10480 O  O   . GLU B 1 684 ? 138.901 113.791 119.336 1.00 50.67  ?  673 GLU B O   1 
ATOM   10481 C  CB  . GLU B 1 684 ? 138.930 114.881 122.378 1.00 50.67  ?  673 GLU B CB  1 
ATOM   10482 C  CG  . GLU B 1 684 ? 139.232 114.218 123.706 1.00 50.67  ?  673 GLU B CG  1 
ATOM   10483 C  CD  . GLU B 1 684 ? 138.765 115.039 124.886 1.00 50.67  ?  673 GLU B CD  1 
ATOM   10484 O  OE1 . GLU B 1 684 ? 139.284 114.829 125.999 1.00 50.67  ?  673 GLU B OE1 1 
ATOM   10485 O  OE2 . GLU B 1 684 ? 137.888 115.902 124.697 1.00 50.67  -1 673 GLU B OE2 1 
ATOM   10486 N  N   . PHE B 1 685 ? 139.358 115.973 119.407 1.00 54.54  ?  674 PHE B N   1 
ATOM   10487 C  CA  . PHE B 1 685 ? 138.808 116.222 118.073 1.00 54.54  ?  674 PHE B CA  1 
ATOM   10488 C  C   . PHE B 1 685 ? 139.740 115.665 117.009 1.00 54.54  ?  674 PHE B C   1 
ATOM   10489 O  O   . PHE B 1 685 ? 139.287 115.135 116.003 1.00 54.54  ?  674 PHE B O   1 
ATOM   10490 C  CB  . PHE B 1 685 ? 138.568 117.709 117.830 1.00 54.54  ?  674 PHE B CB  1 
ATOM   10491 C  CG  . PHE B 1 685 ? 137.245 118.207 118.326 1.00 54.54  ?  674 PHE B CG  1 
ATOM   10492 C  CD1 . PHE B 1 685 ? 137.175 119.059 119.413 1.00 54.54  ?  674 PHE B CD1 1 
ATOM   10493 C  CD2 . PHE B 1 685 ? 136.072 117.833 117.697 1.00 54.54  ?  674 PHE B CD2 1 
ATOM   10494 C  CE1 . PHE B 1 685 ? 135.959 119.523 119.868 1.00 54.54  ?  674 PHE B CE1 1 
ATOM   10495 C  CE2 . PHE B 1 685 ? 134.851 118.293 118.148 1.00 54.54  ?  674 PHE B CE2 1 
ATOM   10496 C  CZ  . PHE B 1 685 ? 134.794 119.140 119.235 1.00 54.54  ?  674 PHE B CZ  1 
ATOM   10497 N  N   . ILE B 1 686 ? 141.036 115.755 117.238 1.00 57.16  ?  675 ILE B N   1 
ATOM   10498 C  CA  . ILE B 1 686 ? 141.988 115.213 116.296 1.00 57.16  ?  675 ILE B CA  1 
ATOM   10499 C  C   . ILE B 1 686 ? 141.936 113.691 116.275 1.00 57.16  ?  675 ILE B C   1 
ATOM   10500 O  O   . ILE B 1 686 ? 142.097 113.082 115.222 1.00 57.16  ?  675 ILE B O   1 
ATOM   10501 C  CB  . ILE B 1 686 ? 143.403 115.712 116.624 1.00 57.16  ?  675 ILE B CB  1 
ATOM   10502 C  CG1 . ILE B 1 686 ? 143.466 117.223 116.396 1.00 57.16  ?  675 ILE B CG1 1 
ATOM   10503 C  CG2 . ILE B 1 686 ? 144.443 115.000 115.780 1.00 57.16  ?  675 ILE B CG2 1 
ATOM   10504 C  CD1 . ILE B 1 686 ? 144.673 117.896 116.999 1.00 57.16  ?  675 ILE B CD1 1 
ATOM   10505 N  N   . ARG B 1 687 ? 141.688 113.076 117.424 1.00 58.20  ?  676 ARG B N   1 
ATOM   10506 C  CA  . ARG B 1 687 ? 141.648 111.617 117.507 1.00 58.20  ?  676 ARG B CA  1 
ATOM   10507 C  C   . ARG B 1 687 ? 140.423 111.016 116.825 1.00 58.20  ?  676 ARG B C   1 
ATOM   10508 O  O   . ARG B 1 687 ? 140.434 109.845 116.474 1.00 58.20  ?  676 ARG B O   1 
ATOM   10509 C  CB  . ARG B 1 687 ? 141.775 111.169 118.963 1.00 58.20  ?  676 ARG B CB  1 
ATOM   10510 C  CG  . ARG B 1 687 ? 143.196 111.317 119.472 1.00 58.20  ?  676 ARG B CG  1 
ATOM   10511 C  CD  . ARG B 1 687 ? 143.284 111.307 120.982 1.00 58.20  ?  676 ARG B CD  1 
ATOM   10512 N  NE  . ARG B 1 687 ? 144.640 111.626 121.407 1.00 58.20  ?  676 ARG B NE  1 
ATOM   10513 C  CZ  . ARG B 1 687 ? 145.023 111.738 122.672 1.00 58.20  ?  676 ARG B CZ  1 
ATOM   10514 N  NH1 . ARG B 1 687 ? 144.148 111.558 123.649 1.00 58.20  1  676 ARG B NH1 1 
ATOM   10515 N  NH2 . ARG B 1 687 ? 146.281 112.034 122.958 1.00 58.20  ?  676 ARG B NH2 1 
ATOM   10516 N  N   . ILE B 1 688 ? 139.389 111.818 116.625 1.00 63.26  ?  677 ILE B N   1 
ATOM   10517 C  CA  . ILE B 1 688 ? 138.211 111.356 115.907 1.00 63.26  ?  677 ILE B CA  1 
ATOM   10518 C  C   . ILE B 1 688 ? 138.278 111.854 114.473 1.00 63.26  ?  677 ILE B C   1 
ATOM   10519 O  O   . ILE B 1 688 ? 137.278 111.833 113.768 1.00 63.26  ?  677 ILE B O   1 
ATOM   10520 C  CB  . ILE B 1 688 ? 136.912 111.807 116.596 1.00 63.26  ?  677 ILE B CB  1 
ATOM   10521 C  CG1 . ILE B 1 688 ? 136.860 113.330 116.704 1.00 63.26  ?  677 ILE B CG1 1 
ATOM   10522 C  CG2 . ILE B 1 688 ? 136.795 111.163 117.968 1.00 63.26  ?  677 ILE B CG2 1 
ATOM   10523 C  CD1 . ILE B 1 688 ? 135.522 113.854 117.171 1.00 63.26  ?  677 ILE B CD1 1 
ATOM   10524 N  N   . LYS B 1 689 ? 139.463 112.273 114.042 1.00 60.40  ?  678 LYS B N   1 
ATOM   10525 C  CA  . LYS B 1 689 ? 139.752 112.799 112.695 1.00 60.40  ?  678 LYS B CA  1 
ATOM   10526 C  C   . LYS B 1 689 ? 139.064 114.104 112.306 1.00 60.40  ?  678 LYS B C   1 
ATOM   10527 O  O   . LYS B 1 689 ? 138.709 114.294 111.158 1.00 60.40  ?  678 LYS B O   1 
ATOM   10528 C  CB  . LYS B 1 689 ? 139.596 111.754 111.571 1.00 30.00  ?  678 LYS B CB  1 
ATOM   10529 C  CG  . LYS B 1 689 ? 140.232 110.424 111.880 1.00 30.00  ?  678 LYS B CG  1 
ATOM   10530 C  CD  . LYS B 1 689 ? 141.674 110.636 112.276 1.00 30.00  ?  678 LYS B CD  1 
ATOM   10531 C  CE  . LYS B 1 689 ? 142.307 109.350 112.755 1.00 30.00  ?  678 LYS B CE  1 
ATOM   10532 N  NZ  . LYS B 1 689 ? 143.725 109.582 113.128 1.00 30.00  1  678 LYS B NZ  1 
ATOM   10533 N  N   . VAL B 1 690 ? 138.850 115.026 113.219 1.00 53.57  ?  679 VAL B N   1 
ATOM   10534 C  CA  . VAL B 1 690 ? 138.260 116.286 112.815 1.00 53.57  ?  679 VAL B CA  1 
ATOM   10535 C  C   . VAL B 1 690 ? 139.423 117.249 112.739 1.00 53.57  ?  679 VAL B C   1 
ATOM   10536 O  O   . VAL B 1 690 ? 140.195 117.359 113.678 1.00 53.57  ?  679 VAL B O   1 
ATOM   10537 C  CB  . VAL B 1 690 ? 137.171 116.761 113.787 1.00 53.57  ?  679 VAL B CB  1 
ATOM   10538 C  CG1 . VAL B 1 690 ? 136.852 118.228 113.596 1.00 53.57  ?  679 VAL B CG1 1 
ATOM   10539 C  CG2 . VAL B 1 690 ? 135.928 115.905 113.641 1.00 53.57  ?  679 VAL B CG2 1 
ATOM   10540 N  N   . ASP B 1 691 ? 139.617 117.875 111.589 1.00 51.13  ?  680 ASP B N   1 
ATOM   10541 C  CA  . ASP B 1 691 ? 140.694 118.839 111.462 1.00 51.13  ?  680 ASP B CA  1 
ATOM   10542 C  C   . ASP B 1 691 ? 140.291 120.065 112.238 1.00 51.13  ?  680 ASP B C   1 
ATOM   10543 O  O   . ASP B 1 691 ? 139.172 120.497 112.149 1.00 51.13  ?  680 ASP B O   1 
ATOM   10544 C  CB  . ASP B 1 691 ? 140.956 119.154 110.006 1.00 51.13  ?  680 ASP B CB  1 
ATOM   10545 C  CG  . ASP B 1 691 ? 141.674 118.035 109.302 1.00 51.13  ?  680 ASP B CG  1 
ATOM   10546 O  OD1 . ASP B 1 691 ? 142.531 117.395 109.927 1.00 51.13  ?  680 ASP B OD1 1 
ATOM   10547 O  OD2 . ASP B 1 691 ? 141.390 117.781 108.123 1.00 51.13  -1 680 ASP B OD2 1 
ATOM   10548 N  N   . VAL B 1 692 ? 141.216 120.614 112.998 1.00 47.03  ?  681 VAL B N   1 
ATOM   10549 C  CA  . VAL B 1 692 ? 140.965 121.767 113.843 1.00 47.03  ?  681 VAL B CA  1 
ATOM   10550 C  C   . VAL B 1 692 ? 141.828 122.948 113.428 1.00 47.03  ?  681 VAL B C   1 
ATOM   10551 O  O   . VAL B 1 692 ? 142.971 122.778 113.078 1.00 47.03  ?  681 VAL B O   1 
ATOM   10552 C  CB  . VAL B 1 692 ? 141.203 121.419 115.325 1.00 47.03  ?  681 VAL B CB  1 
ATOM   10553 C  CG1 . VAL B 1 692 ? 140.915 122.622 116.214 1.00 47.03  ?  681 VAL B CG1 1 
ATOM   10554 C  CG2 . VAL B 1 692 ? 140.332 120.245 115.732 1.00 47.03  ?  681 VAL B CG2 1 
ATOM   10555 N  N   . TYR B 1 693 ? 141.231 124.132 113.357 1.00 42.91  ?  682 TYR B N   1 
ATOM   10556 C  CA  . TYR B 1 693 ? 141.929 125.351 112.970 1.00 42.91  ?  682 TYR B CA  1 
ATOM   10557 C  C   . TYR B 1 693 ? 141.698 126.447 113.962 1.00 42.91  ?  682 TYR B C   1 
ATOM   10558 O  O   . TYR B 1 693 ? 140.599 126.631 114.433 1.00 42.91  ?  682 TYR B O   1 
ATOM   10559 C  CB  . TYR B 1 693 ? 141.476 125.829 111.592 1.00 42.91  ?  682 TYR B CB  1 
ATOM   10560 C  CG  . TYR B 1 693 ? 141.558 124.754 110.568 1.00 42.91  ?  682 TYR B CG  1 
ATOM   10561 C  CD1 . TYR B 1 693 ? 142.676 124.613 109.781 1.00 42.91  ?  682 TYR B CD1 1 
ATOM   10562 C  CD2 . TYR B 1 693 ? 140.533 123.840 110.423 1.00 42.91  ?  682 TYR B CD2 1 
ATOM   10563 C  CE1 . TYR B 1 693 ? 142.765 123.603 108.861 1.00 42.91  ?  682 TYR B CE1 1 
ATOM   10564 C  CE2 . TYR B 1 693 ? 140.619 122.818 109.530 1.00 42.91  ?  682 TYR B CE2 1 
ATOM   10565 C  CZ  . TYR B 1 693 ? 141.733 122.709 108.745 1.00 42.91  ?  682 TYR B CZ  1 
ATOM   10566 O  OH  . TYR B 1 693 ? 141.807 121.703 107.830 1.00 42.91  ?  682 TYR B OH  1 
ATOM   10567 N  N   . ILE B 1 694 ? 142.749 127.167 114.298 1.00 41.89  ?  683 ILE B N   1 
ATOM   10568 C  CA  . ILE B 1 694 ? 142.640 128.294 115.200 1.00 41.89  ?  683 ILE B CA  1 
ATOM   10569 C  C   . ILE B 1 694 ? 142.983 129.506 114.359 1.00 41.89  ?  683 ILE B C   1 
ATOM   10570 O  O   . ILE B 1 694 ? 144.005 129.530 113.717 1.00 41.89  ?  683 ILE B O   1 
ATOM   10571 C  CB  . ILE B 1 694 ? 143.543 128.127 116.429 1.00 41.89  ?  683 ILE B CB  1 
ATOM   10572 C  CG1 . ILE B 1 694 ? 143.180 126.831 117.153 1.00 41.89  ?  683 ILE B CG1 1 
ATOM   10573 C  CG2 . ILE B 1 694 ? 143.400 129.317 117.360 1.00 41.89  ?  683 ILE B CG2 1 
ATOM   10574 C  CD1 . ILE B 1 694 ? 143.819 126.659 118.502 1.00 41.89  ?  683 ILE B CD1 1 
ATOM   10575 N  N   . VAL B 1 695 ? 142.102 130.498 114.320 1.00 41.51  ?  684 VAL B N   1 
ATOM   10576 C  CA  . VAL B 1 695 ? 142.306 131.652 113.462 1.00 41.51  ?  684 VAL B CA  1 
ATOM   10577 C  C   . VAL B 1 695 ? 142.174 132.919 114.287 1.00 41.51  ?  684 VAL B C   1 
ATOM   10578 O  O   . VAL B 1 695 ? 141.617 132.924 115.383 1.00 41.51  ?  684 VAL B O   1 
ATOM   10579 C  CB  . VAL B 1 695 ? 141.320 131.674 112.282 1.00 41.51  ?  684 VAL B CB  1 
ATOM   10580 C  CG1 . VAL B 1 695 ? 141.426 130.399 111.489 1.00 41.51  ?  684 VAL B CG1 1 
ATOM   10581 C  CG2 . VAL B 1 695 ? 139.914 131.871 112.784 1.00 41.51  ?  684 VAL B CG2 1 
ATOM   10582 N  N   . GLY B 1 696 ? 142.716 134.003 113.748 1.00 45.86  ?  685 GLY B N   1 
ATOM   10583 C  CA  . GLY B 1 696 ? 142.487 135.320 114.291 1.00 45.86  ?  685 GLY B CA  1 
ATOM   10584 C  C   . GLY B 1 696 ? 143.363 135.730 115.447 1.00 45.86  ?  685 GLY B C   1 
ATOM   10585 O  O   . GLY B 1 696 ? 143.079 136.748 116.079 1.00 45.86  ?  685 GLY B O   1 
ATOM   10586 N  N   . THR B 1 697 ? 144.415 134.985 115.748 1.00 50.77  ?  686 THR B N   1 
ATOM   10587 C  CA  . THR B 1 697 ? 145.317 135.336 116.830 1.00 50.77  ?  686 THR B CA  1 
ATOM   10588 C  C   . THR B 1 697 ? 146.504 136.119 116.288 1.00 50.77  ?  686 THR B C   1 
ATOM   10589 O  O   . THR B 1 697 ? 146.788 136.099 115.090 1.00 50.77  ?  686 THR B O   1 
ATOM   10590 C  CB  . THR B 1 697 ? 145.802 134.083 117.554 1.00 50.77  ?  686 THR B CB  1 
ATOM   10591 O  OG1 . THR B 1 697 ? 146.649 133.330 116.687 1.00 50.77  ?  686 THR B OG1 1 
ATOM   10592 C  CG2 . THR B 1 697 ? 144.638 133.225 117.942 1.00 50.77  ?  686 THR B CG2 1 
ATOM   10593 N  N   . ASP B 1 698 ? 147.182 136.833 117.180 1.00 58.02  ?  687 ASP B N   1 
ATOM   10594 C  CA  . ASP B 1 698 ? 148.405 137.524 116.807 1.00 58.02  ?  687 ASP B CA  1 
ATOM   10595 C  C   . ASP B 1 698 ? 149.623 136.668 117.151 1.00 58.02  ?  687 ASP B C   1 
ATOM   10596 O  O   . ASP B 1 698 ? 149.512 135.548 117.651 1.00 58.02  ?  687 ASP B O   1 
ATOM   10597 C  CB  . ASP B 1 698 ? 148.472 138.894 117.476 1.00 58.02  ?  687 ASP B CB  1 
ATOM   10598 C  CG  . ASP B 1 698 ? 148.338 138.818 118.975 1.00 58.02  ?  687 ASP B CG  1 
ATOM   10599 O  OD1 . ASP B 1 698 ? 149.049 139.563 119.678 1.00 58.02  ?  687 ASP B OD1 1 
ATOM   10600 O  OD2 . ASP B 1 698 ? 147.516 138.010 119.452 1.00 58.02  -1 687 ASP B OD2 1 
ATOM   10601 N  N   . ASP B 1 699 ? 150.809 137.207 116.876 1.00 61.71  ?  688 ASP B N   1 
ATOM   10602 C  CA  . ASP B 1 699 ? 152.045 136.442 116.986 1.00 61.71  ?  688 ASP B CA  1 
ATOM   10603 C  C   . ASP B 1 699 ? 152.477 136.240 118.432 1.00 61.71  ?  688 ASP B C   1 
ATOM   10604 O  O   . ASP B 1 699 ? 153.006 135.173 118.778 1.00 61.71  ?  688 ASP B O   1 
ATOM   10605 C  CB  . ASP B 1 699 ? 153.139 137.153 116.198 1.00 61.71  ?  688 ASP B CB  1 
ATOM   10606 C  CG  . ASP B 1 699 ? 152.818 137.242 114.720 1.00 61.71  ?  688 ASP B CG  1 
ATOM   10607 O  OD1 . ASP B 1 699 ? 151.630 137.088 114.364 1.00 61.71  ?  688 ASP B OD1 1 
ATOM   10608 O  OD2 . ASP B 1 699 ? 153.732 137.505 113.916 1.00 61.71  -1 688 ASP B OD2 1 
ATOM   10609 N  N   . ASP B 1 700 ? 152.271 137.251 119.276 1.00 61.99  ?  689 ASP B N   1 
ATOM   10610 C  CA  . ASP B 1 700 ? 152.512 137.101 120.703 1.00 61.99  ?  689 ASP B CA  1 
ATOM   10611 C  C   . ASP B 1 700 ? 151.738 135.928 121.273 1.00 61.99  ?  689 ASP B C   1 
ATOM   10612 O  O   . ASP B 1 700 ? 152.234 135.228 122.160 1.00 61.99  ?  689 ASP B O   1 
ATOM   10613 C  CB  . ASP B 1 700 ? 152.111 138.378 121.429 1.00 61.99  ?  689 ASP B CB  1 
ATOM   10614 C  CG  . ASP B 1 700 ? 152.864 139.586 120.938 1.00 61.99  ?  689 ASP B CG  1 
ATOM   10615 O  OD1 . ASP B 1 700 ? 154.050 139.742 121.284 1.00 61.99  ?  689 ASP B OD1 1 
ATOM   10616 O  OD2 . ASP B 1 700 ? 152.266 140.386 120.191 1.00 61.99  -1 689 ASP B OD2 1 
ATOM   10617 N  N   . PHE B 1 701 ? 150.527 135.698 120.767 1.00 55.83  ?  690 PHE B N   1 
ATOM   10618 C  CA  . PHE B 1 701 ? 149.697 134.602 121.244 1.00 55.83  ?  690 PHE B CA  1 
ATOM   10619 C  C   . PHE B 1 701 ? 150.367 133.257 120.999 1.00 55.83  ?  690 PHE B C   1 
ATOM   10620 O  O   . PHE B 1 701 ? 150.405 132.399 121.886 1.00 55.83  ?  690 PHE B O   1 
ATOM   10621 C  CB  . PHE B 1 701 ? 148.336 134.673 120.555 1.00 55.83  ?  690 PHE B CB  1 
ATOM   10622 C  CG  . PHE B 1 701 ? 147.288 133.801 121.171 1.00 55.83  ?  690 PHE B CG  1 
ATOM   10623 C  CD1 . PHE B 1 701 ? 147.121 132.498 120.751 1.00 55.83  ?  690 PHE B CD1 1 
ATOM   10624 C  CD2 . PHE B 1 701 ? 146.455 134.292 122.156 1.00 55.83  ?  690 PHE B CD2 1 
ATOM   10625 C  CE1 . PHE B 1 701 ? 146.162 131.704 121.309 1.00 55.83  ?  690 PHE B CE1 1 
ATOM   10626 C  CE2 . PHE B 1 701 ? 145.491 133.497 122.716 1.00 55.83  ?  690 PHE B CE2 1 
ATOM   10627 C  CZ  . PHE B 1 701 ? 145.344 132.205 122.288 1.00 55.83  ?  690 PHE B CZ  1 
ATOM   10628 N  N   . ILE B 1 702 ? 150.899 133.050 119.795 1.00 57.87  ?  691 ILE B N   1 
ATOM   10629 C  CA  . ILE B 1 702 ? 151.489 131.756 119.476 1.00 57.87  ?  691 ILE B CA  1 
ATOM   10630 C  C   . ILE B 1 702 ? 152.839 131.578 120.156 1.00 57.87  ?  691 ILE B C   1 
ATOM   10631 O  O   . ILE B 1 702 ? 153.184 130.465 120.570 1.00 57.87  ?  691 ILE B O   1 
ATOM   10632 C  CB  . ILE B 1 702 ? 151.579 131.584 117.954 1.00 57.87  ?  691 ILE B CB  1 
ATOM   10633 C  CG1 . ILE B 1 702 ? 150.228 131.919 117.331 1.00 57.87  ?  691 ILE B CG1 1 
ATOM   10634 C  CG2 . ILE B 1 702 ? 151.981 130.171 117.599 1.00 57.87  ?  691 ILE B CG2 1 
ATOM   10635 C  CD1 . ILE B 1 702 ? 150.260 132.120 115.846 1.00 57.87  ?  691 ILE B CD1 1 
ATOM   10636 N  N   . GLU B 1 703 ? 153.510 132.692 120.385 1.00 61.59  ?  692 GLU B N   1 
ATOM   10637 C  CA  . GLU B 1 703 ? 154.754 132.694 121.098 1.00 61.59  ?  692 GLU B CA  1 
ATOM   10638 C  C   . GLU B 1 703 ? 154.441 132.199 122.507 1.00 61.59  ?  692 GLU B C   1 
ATOM   10639 O  O   . GLU B 1 703 ? 155.107 131.315 123.008 1.00 61.59  ?  692 GLU B O   1 
ATOM   10640 C  CB  . GLU B 1 703 ? 155.304 134.113 121.136 1.00 61.59  ?  692 GLU B CB  1 
ATOM   10641 C  CG  . GLU B 1 703 ? 156.792 134.215 121.362 1.00 61.59  ?  692 GLU B CG  1 
ATOM   10642 C  CD  . GLU B 1 703 ? 157.308 135.616 121.123 1.00 61.59  ?  692 GLU B CD  1 
ATOM   10643 O  OE1 . GLU B 1 703 ? 158.540 135.780 120.971 1.00 61.59  ?  692 GLU B OE1 1 
ATOM   10644 O  OE2 . GLU B 1 703 ? 156.484 136.558 121.079 1.00 61.59  -1 692 GLU B OE2 1 
ATOM   10645 N  N   . LYS B 1 704 ? 153.407 132.757 123.131 1.00 59.24  ?  693 LYS B N   1 
ATOM   10646 C  CA  . LYS B 1 704 ? 153.011 132.364 124.476 1.00 59.24  ?  693 LYS B CA  1 
ATOM   10647 C  C   . LYS B 1 704 ? 152.597 130.903 124.518 1.00 59.24  ?  693 LYS B C   1 
ATOM   10648 O  O   . LYS B 1 704 ? 152.968 130.177 125.442 1.00 59.24  ?  693 LYS B O   1 
ATOM   10649 C  CB  . LYS B 1 704 ? 151.885 133.255 124.979 1.00 59.24  ?  693 LYS B CB  1 
ATOM   10650 C  CG  . LYS B 1 704 ? 152.332 134.632 125.383 1.00 59.24  ?  693 LYS B CG  1 
ATOM   10651 C  CD  . LYS B 1 704 ? 151.246 135.347 126.147 1.00 59.24  ?  693 LYS B CD  1 
ATOM   10652 C  CE  . LYS B 1 704 ? 151.728 136.675 126.692 1.00 59.24  ?  693 LYS B CE  1 
ATOM   10653 N  NZ  . LYS B 1 704 ? 151.981 137.656 125.610 1.00 59.24  1  693 LYS B NZ  1 
ATOM   10654 N  N   . LEU B 1 705 ? 151.837 130.454 123.524 1.00 57.34  ?  694 LEU B N   1 
ATOM   10655 C  CA  . LEU B 1 705 ? 151.393 129.068 123.470 1.00 57.34  ?  694 LEU B CA  1 
ATOM   10656 C  C   . LEU B 1 705 ? 152.545 128.091 123.285 1.00 57.34  ?  694 LEU B C   1 
ATOM   10657 O  O   . LEU B 1 705 ? 152.399 126.912 123.613 1.00 57.34  ?  694 LEU B O   1 
ATOM   10658 C  CB  . LEU B 1 705 ? 150.378 128.906 122.343 1.00 57.34  ?  694 LEU B CB  1 
ATOM   10659 C  CG  . LEU B 1 705 ? 149.266 127.877 122.493 1.00 57.34  ?  694 LEU B CG  1 
ATOM   10660 C  CD1 . LEU B 1 705 ? 148.623 127.957 123.852 1.00 57.34  ?  694 LEU B CD1 1 
ATOM   10661 C  CD2 . LEU B 1 705 ? 148.242 128.113 121.427 1.00 57.34  ?  694 LEU B CD2 1 
ATOM   10662 N  N   . ASN B 1 706 ? 153.674 128.544 122.745 1.00 61.10  ?  695 ASN B N   1 
ATOM   10663 C  CA  . ASN B 1 706 ? 154.825 127.658 122.605 1.00 61.10  ?  695 ASN B CA  1 
ATOM   10664 C  C   . ASN B 1 706 ? 155.482 127.354 123.944 1.00 61.10  ?  695 ASN B C   1 
ATOM   10665 O  O   . ASN B 1 706 ? 156.124 126.310 124.090 1.00 61.10  ?  695 ASN B O   1 
ATOM   10666 C  CB  . ASN B 1 706 ? 155.848 128.271 121.659 1.00 61.10  ?  695 ASN B CB  1 
ATOM   10667 C  CG  . ASN B 1 706 ? 155.502 128.050 120.218 1.00 61.10  ?  695 ASN B CG  1 
ATOM   10668 O  OD1 . ASN B 1 706 ? 155.542 126.927 119.725 1.00 61.10  ?  695 ASN B OD1 1 
ATOM   10669 N  ND2 . ASN B 1 706 ? 155.147 129.121 119.527 1.00 61.10  ?  695 ASN B ND2 1 
ATOM   10670 N  N   . ARG B 1 707 ? 155.354 128.251 124.922 1.00 60.80  ?  696 ARG B N   1 
ATOM   10671 C  CA  . ARG B 1 707 ? 155.963 128.013 126.224 1.00 60.80  ?  696 ARG B CA  1 
ATOM   10672 C  C   . ARG B 1 707 ? 155.190 126.987 127.033 1.00 60.80  ?  696 ARG B C   1 
ATOM   10673 O  O   . ARG B 1 707 ? 155.763 126.333 127.906 1.00 60.80  ?  696 ARG B O   1 
ATOM   10674 C  CB  . ARG B 1 707 ? 156.057 129.312 127.011 1.00 60.80  ?  696 ARG B CB  1 
ATOM   10675 C  CG  . ARG B 1 707 ? 156.833 130.396 126.329 1.00 60.80  ?  696 ARG B CG  1 
ATOM   10676 C  CD  . ARG B 1 707 ? 156.676 131.690 127.082 1.00 60.80  ?  696 ARG B CD  1 
ATOM   10677 N  NE  . ARG B 1 707 ? 156.786 132.847 126.203 1.00 60.80  ?  696 ARG B NE  1 
ATOM   10678 C  CZ  . ARG B 1 707 ? 156.226 134.025 126.454 1.00 60.80  ?  696 ARG B CZ  1 
ATOM   10679 N  NH1 . ARG B 1 707 ? 156.375 135.026 125.599 1.00 60.80  1  696 ARG B NH1 1 
ATOM   10680 N  NH2 . ARG B 1 707 ? 155.517 134.198 127.559 1.00 60.80  ?  696 ARG B NH2 1 
ATOM   10681 N  N   . TYR B 1 708 ? 153.898 126.837 126.768 1.00 56.77  ?  697 TYR B N   1 
ATOM   10682 C  CA  . TYR B 1 708 ? 153.065 125.931 127.541 1.00 56.77  ?  697 TYR B CA  1 
ATOM   10683 C  C   . TYR B 1 708 ? 153.264 124.476 127.181 1.00 56.77  ?  697 TYR B C   1 
ATOM   10684 O  O   . TYR B 1 708 ? 152.537 123.640 127.720 1.00 56.77  ?  697 TYR B O   1 
ATOM   10685 C  CB  . TYR B 1 708 ? 151.597 126.279 127.349 1.00 56.77  ?  697 TYR B CB  1 
ATOM   10686 C  CG  . TYR B 1 708 ? 151.144 127.515 128.064 1.00 56.77  ?  697 TYR B CG  1 
ATOM   10687 C  CD1 . TYR B 1 708 ? 151.152 128.737 127.430 1.00 56.77  ?  697 TYR B CD1 1 
ATOM   10688 C  CD2 . TYR B 1 708 ? 150.681 127.457 129.364 1.00 56.77  ?  697 TYR B CD2 1 
ATOM   10689 C  CE1 . TYR B 1 708 ? 150.726 129.868 128.070 1.00 56.77  ?  697 TYR B CE1 1 
ATOM   10690 C  CE2 . TYR B 1 708 ? 150.254 128.584 130.012 1.00 56.77  ?  697 TYR B CE2 1 
ATOM   10691 C  CZ  . TYR B 1 708 ? 150.277 129.787 129.361 1.00 56.77  ?  697 TYR B CZ  1 
ATOM   10692 O  OH  . TYR B 1 708 ? 149.853 130.920 130.001 1.00 56.77  ?  697 TYR B OH  1 
ATOM   10693 N  N   . GLU B 1 709 ? 154.212 124.148 126.308 1.00 60.86  ?  698 GLU B N   1 
ATOM   10694 C  CA  . GLU B 1 709 ? 154.338 122.808 125.743 1.00 60.86  ?  698 GLU B CA  1 
ATOM   10695 C  C   . GLU B 1 709 ? 152.987 122.328 125.216 1.00 60.86  ?  698 GLU B C   1 
ATOM   10696 O  O   . GLU B 1 709 ? 152.506 121.241 125.533 1.00 60.86  ?  698 GLU B O   1 
ATOM   10697 C  CB  . GLU B 1 709 ? 154.907 121.817 126.759 1.00 60.86  ?  698 GLU B CB  1 
ATOM   10698 C  CG  . GLU B 1 709 ? 156.361 122.034 127.140 1.00 60.86  ?  698 GLU B CG  1 
ATOM   10699 C  CD  . GLU B 1 709 ? 156.553 122.236 128.629 1.00 60.86  ?  698 GLU B CD  1 
ATOM   10700 O  OE1 . GLU B 1 709 ? 155.661 122.841 129.262 1.00 60.86  ?  698 GLU B OE1 1 
ATOM   10701 O  OE2 . GLU B 1 709 ? 157.579 121.770 129.170 1.00 60.86  -1 698 GLU B OE2 1 
ATOM   10702 N  N   . PHE B 1 710 ? 152.368 123.188 124.415 1.00 55.63  ?  699 PHE B N   1 
ATOM   10703 C  CA  . PHE B 1 710 ? 151.075 122.922 123.805 1.00 55.63  ?  699 PHE B CA  1 
ATOM   10704 C  C   . PHE B 1 710 ? 151.216 122.097 122.538 1.00 55.63  ?  699 PHE B C   1 
ATOM   10705 O  O   . PHE B 1 710 ? 150.466 121.140 122.332 1.00 55.63  ?  699 PHE B O   1 
ATOM   10706 C  CB  . PHE B 1 710 ? 150.380 124.249 123.507 1.00 55.63  ?  699 PHE B CB  1 
ATOM   10707 C  CG  . PHE B 1 710 ? 149.015 124.118 122.914 1.00 55.63  ?  699 PHE B CG  1 
ATOM   10708 C  CD1 . PHE B 1 710 ? 148.815 124.322 121.570 1.00 55.63  ?  699 PHE B CD1 1 
ATOM   10709 C  CD2 . PHE B 1 710 ? 147.924 123.841 123.707 1.00 55.63  ?  699 PHE B CD2 1 
ATOM   10710 C  CE1 . PHE B 1 710 ? 147.565 124.226 121.028 1.00 55.63  ?  699 PHE B CE1 1 
ATOM   10711 C  CE2 . PHE B 1 710 ? 146.675 123.746 123.165 1.00 55.63  ?  699 PHE B CE2 1 
ATOM   10712 C  CZ  . PHE B 1 710 ? 146.495 123.937 121.827 1.00 55.63  ?  699 PHE B CZ  1 
ATOM   10713 N  N   . PHE B 1 711 ? 152.181 122.435 121.698 1.00 56.28  ?  700 PHE B N   1 
ATOM   10714 C  CA  . PHE B 1 711 ? 152.381 121.741 120.442 1.00 56.28  ?  700 PHE B CA  1 
ATOM   10715 C  C   . PHE B 1 711 ? 153.233 120.504 120.644 1.00 56.28  ?  700 PHE B C   1 
ATOM   10716 O  O   . PHE B 1 711 ? 154.162 120.485 121.452 1.00 56.28  ?  700 PHE B O   1 
ATOM   10717 C  CB  . PHE B 1 711 ? 153.033 122.661 119.417 1.00 56.28  ?  700 PHE B CB  1 
ATOM   10718 C  CG  . PHE B 1 711 ? 152.258 123.896 119.160 1.00 56.28  ?  700 PHE B CG  1 
ATOM   10719 C  CD1 . PHE B 1 711 ? 151.011 123.829 118.581 1.00 56.28  ?  700 PHE B CD1 1 
ATOM   10720 C  CD2 . PHE B 1 711 ? 152.758 125.125 119.517 1.00 56.28  ?  700 PHE B CD2 1 
ATOM   10721 C  CE1 . PHE B 1 711 ? 150.291 124.961 118.353 1.00 56.28  ?  700 PHE B CE1 1 
ATOM   10722 C  CE2 . PHE B 1 711 ? 152.041 126.260 119.288 1.00 56.28  ?  700 PHE B CE2 1 
ATOM   10723 C  CZ  . PHE B 1 711 ? 150.807 126.179 118.707 1.00 56.28  ?  700 PHE B CZ  1 
ATOM   10724 N  N   . ASP B 1 712 ? 152.907 119.473 119.893 1.00 59.50  ?  701 ASP B N   1 
ATOM   10725 C  CA  . ASP B 1 712 ? 153.598 118.193 119.918 1.00 59.50  ?  701 ASP B CA  1 
ATOM   10726 C  C   . ASP B 1 712 ? 153.229 117.487 118.624 1.00 59.50  ?  701 ASP B C   1 
ATOM   10727 O  O   . ASP B 1 712 ? 152.723 118.113 117.687 1.00 59.50  ?  701 ASP B O   1 
ATOM   10728 C  CB  . ASP B 1 712 ? 153.221 117.380 121.156 1.00 59.50  ?  701 ASP B CB  1 
ATOM   10729 C  CG  . ASP B 1 712 ? 151.742 117.078 121.223 1.00 59.50  ?  701 ASP B CG  1 
ATOM   10730 O  OD1 . ASP B 1 712 ? 150.945 117.902 120.747 1.00 59.50  ?  701 ASP B OD1 1 
ATOM   10731 O  OD2 . ASP B 1 712 ? 151.369 116.013 121.749 1.00 59.50  -1 701 ASP B OD2 1 
ATOM   10732 N  N   . GLY B 1 713 ? 153.509 116.192 118.550 1.00 61.42  ?  702 GLY B N   1 
ATOM   10733 C  CA  . GLY B 1 713 ? 152.829 115.379 117.563 1.00 61.42  ?  702 GLY B CA  1 
ATOM   10734 C  C   . GLY B 1 713 ? 151.346 115.328 117.876 1.00 61.42  ?  702 GLY B C   1 
ATOM   10735 O  O   . GLY B 1 713 ? 150.941 115.308 119.039 1.00 61.42  ?  702 GLY B O   1 
ATOM   10736 N  N   . GLU B 1 714 ? 150.534 115.330 116.828 1.00 61.54  ?  703 GLU B N   1 
ATOM   10737 C  CA  . GLU B 1 714 ? 149.077 115.309 116.835 1.00 61.54  ?  703 GLU B CA  1 
ATOM   10738 C  C   . GLU B 1 714 ? 148.445 116.641 117.248 1.00 61.54  ?  703 GLU B C   1 
ATOM   10739 O  O   . GLU B 1 714 ? 147.235 116.782 117.121 1.00 61.54  ?  703 GLU B O   1 
ATOM   10740 C  CB  . GLU B 1 714 ? 148.508 114.262 117.814 1.00 61.54  ?  703 GLU B CB  1 
ATOM   10741 C  CG  . GLU B 1 714 ? 147.032 114.002 117.719 1.00 61.54  ?  703 GLU B CG  1 
ATOM   10742 C  CD  . GLU B 1 714 ? 146.424 113.705 119.063 1.00 61.54  ?  703 GLU B CD  1 
ATOM   10743 O  OE1 . GLU B 1 714 ? 146.758 112.661 119.655 1.00 61.54  ?  703 GLU B OE1 1 
ATOM   10744 O  OE2 . GLU B 1 714 ? 145.618 114.526 119.532 1.00 61.54  -1 703 GLU B OE2 1 
ATOM   10745 N  N   . VAL B 1 715 ? 149.214 117.649 117.640 1.00 57.03  ?  704 VAL B N   1 
ATOM   10746 C  CA  . VAL B 1 715 ? 148.716 119.017 117.738 1.00 57.03  ?  704 VAL B CA  1 
ATOM   10747 C  C   . VAL B 1 715 ? 149.845 119.922 117.288 1.00 57.03  ?  704 VAL B C   1 
ATOM   10748 O  O   . VAL B 1 715 ? 150.785 120.182 118.042 1.00 57.03  ?  704 VAL B O   1 
ATOM   10749 C  CB  . VAL B 1 715 ? 148.239 119.381 119.156 1.00 57.03  ?  704 VAL B CB  1 
ATOM   10750 C  CG1 . VAL B 1 715 ? 148.003 120.870 119.271 1.00 57.03  ?  704 VAL B CG1 1 
ATOM   10751 C  CG2 . VAL B 1 715 ? 146.966 118.661 119.482 1.00 57.03  ?  704 VAL B CG2 1 
ATOM   10752 N  N   . LYS B 1 716 ? 149.771 120.392 116.055 1.00 54.03  ?  705 LYS B N   1 
ATOM   10753 C  CA  . LYS B 1 716 ? 150.870 121.086 115.416 1.00 54.03  ?  705 LYS B CA  1 
ATOM   10754 C  C   . LYS B 1 716 ? 150.522 122.550 115.213 1.00 54.03  ?  705 LYS B C   1 
ATOM   10755 O  O   . LYS B 1 716 ? 149.357 122.940 115.219 1.00 54.03  ?  705 LYS B O   1 
ATOM   10756 C  CB  . LYS B 1 716 ? 151.205 120.418 114.084 1.00 54.03  ?  705 LYS B CB  1 
ATOM   10757 C  CG  . LYS B 1 716 ? 151.331 118.915 114.175 1.00 54.03  ?  705 LYS B CG  1 
ATOM   10758 C  CD  . LYS B 1 716 ? 151.122 118.280 112.827 1.00 54.03  ?  705 LYS B CD  1 
ATOM   10759 C  CE  . LYS B 1 716 ? 152.172 117.230 112.548 1.00 54.03  ?  705 LYS B CE  1 
ATOM   10760 N  NZ  . LYS B 1 716 ? 152.392 117.055 111.085 1.00 54.03  1  705 LYS B NZ  1 
ATOM   10761 N  N   . SER B 1 717 ? 151.553 123.366 115.027 1.00 52.64  ?  706 SER B N   1 
ATOM   10762 C  CA  . SER B 1 717 ? 151.342 124.776 114.735 1.00 52.64  ?  706 SER B CA  1 
ATOM   10763 C  C   . SER B 1 717 ? 150.743 125.004 113.355 1.00 52.64  ?  706 SER B C   1 
ATOM   10764 O  O   . SER B 1 717 ? 150.478 126.153 112.994 1.00 52.64  ?  706 SER B O   1 
ATOM   10765 C  CB  . SER B 1 717 ? 152.653 125.544 114.838 1.00 52.64  ?  706 SER B CB  1 
ATOM   10766 O  OG  . SER B 1 717 ? 153.586 125.117 113.870 1.00 52.64  ?  706 SER B OG  1 
ATOM   10767 N  N   . SER B 1 718 ? 150.549 123.949 112.570 1.00 49.75  ?  707 SER B N   1 
ATOM   10768 C  CA  . SER B 1 718 ? 149.850 124.049 111.304 1.00 49.75  ?  707 SER B CA  1 
ATOM   10769 C  C   . SER B 1 718 ? 148.374 124.363 111.469 1.00 49.75  ?  707 SER B C   1 
ATOM   10770 O  O   . SER B 1 718 ? 147.718 124.687 110.480 1.00 49.75  ?  707 SER B O   1 
ATOM   10771 C  CB  . SER B 1 718 ? 150.009 122.748 110.536 1.00 49.75  ?  707 SER B CB  1 
ATOM   10772 O  OG  . SER B 1 718 ? 151.276 122.185 110.776 1.00 49.75  ?  707 SER B OG  1 
ATOM   10773 N  N   . ILE B 1 719 ? 147.834 124.266 112.685 1.00 45.40  ?  708 ILE B N   1 
ATOM   10774 C  CA  . ILE B 1 719 ? 146.413 124.518 112.898 1.00 45.40  ?  708 ILE B CA  1 
ATOM   10775 C  C   . ILE B 1 719 ? 146.085 125.995 112.975 1.00 45.40  ?  708 ILE B C   1 
ATOM   10776 O  O   . ILE B 1 719 ? 144.909 126.352 113.017 1.00 45.40  ?  708 ILE B O   1 
ATOM   10777 C  CB  . ILE B 1 719 ? 145.908 123.833 114.180 1.00 45.40  ?  708 ILE B CB  1 
ATOM   10778 C  CG1 . ILE B 1 719 ? 146.440 124.544 115.414 1.00 45.40  ?  708 ILE B CG1 1 
ATOM   10779 C  CG2 . ILE B 1 719 ? 146.311 122.388 114.196 1.00 45.40  ?  708 ILE B CG2 1 
ATOM   10780 C  CD1 . ILE B 1 719 ? 145.838 124.058 116.676 1.00 45.40  ?  708 ILE B CD1 1 
ATOM   10781 N  N   . PHE B 1 720 ? 147.085 126.860 112.983 1.00 44.94  ?  709 PHE B N   1 
ATOM   10782 C  CA  . PHE B 1 720 ? 146.868 128.293 113.062 1.00 44.94  ?  709 PHE B CA  1 
ATOM   10783 C  C   . PHE B 1 720 ? 146.819 128.876 111.661 1.00 44.94  ?  709 PHE B C   1 
ATOM   10784 O  O   . PHE B 1 720 ? 147.715 128.635 110.852 1.00 44.94  ?  709 PHE B O   1 
ATOM   10785 C  CB  . PHE B 1 720 ? 147.956 128.957 113.893 1.00 44.94  ?  709 PHE B CB  1 
ATOM   10786 C  CG  . PHE B 1 720 ? 147.762 128.784 115.352 1.00 44.94  ?  709 PHE B CG  1 
ATOM   10787 C  CD1 . PHE B 1 720 ? 147.076 129.722 116.085 1.00 44.94  ?  709 PHE B CD1 1 
ATOM   10788 C  CD2 . PHE B 1 720 ? 148.236 127.665 115.990 1.00 44.94  ?  709 PHE B CD2 1 
ATOM   10789 C  CE1 . PHE B 1 720 ? 146.887 129.552 117.424 1.00 44.94  ?  709 PHE B CE1 1 
ATOM   10790 C  CE2 . PHE B 1 720 ? 148.042 127.494 117.322 1.00 44.94  ?  709 PHE B CE2 1 
ATOM   10791 C  CZ  . PHE B 1 720 ? 147.369 128.439 118.041 1.00 44.94  ?  709 PHE B CZ  1 
ATOM   10792 N  N   . PHE B 1 721 ? 145.760 129.617 111.378 1.00 41.22  ?  710 PHE B N   1 
ATOM   10793 C  CA  . PHE B 1 721 ? 145.579 130.320 110.125 1.00 41.22  ?  710 PHE B CA  1 
ATOM   10794 C  C   . PHE B 1 721 ? 145.361 131.790 110.420 1.00 41.22  ?  710 PHE B C   1 
ATOM   10795 O  O   . PHE B 1 721 ? 145.127 132.187 111.558 1.00 41.22  ?  710 PHE B O   1 
ATOM   10796 C  CB  . PHE B 1 721 ? 144.412 129.735 109.326 1.00 41.22  ?  710 PHE B CB  1 
ATOM   10797 C  CG  . PHE B 1 721 ? 144.798 128.571 108.492 1.00 41.22  ?  710 PHE B CG  1 
ATOM   10798 C  CD1 . PHE B 1 721 ? 144.913 128.693 107.135 1.00 41.22  ?  710 PHE B CD1 1 
ATOM   10799 C  CD2 . PHE B 1 721 ? 145.084 127.360 109.073 1.00 41.22  ?  710 PHE B CD2 1 
ATOM   10800 C  CE1 . PHE B 1 721 ? 145.289 127.634 106.378 1.00 41.22  ?  710 PHE B CE1 1 
ATOM   10801 C  CE2 . PHE B 1 721 ? 145.464 126.302 108.316 1.00 41.22  ?  710 PHE B CE2 1 
ATOM   10802 C  CZ  . PHE B 1 721 ? 145.565 126.438 106.969 1.00 41.22  ?  710 PHE B CZ  1 
ATOM   10803 N  N   . LEU B 1 722 ? 145.456 132.608 109.380 1.00 41.72  ?  711 LEU B N   1 
ATOM   10804 C  CA  . LEU B 1 722 ? 145.358 134.046 109.573 1.00 41.72  ?  711 LEU B CA  1 
ATOM   10805 C  C   . LEU B 1 722 ? 143.942 134.459 109.943 1.00 41.72  ?  711 LEU B C   1 
ATOM   10806 O  O   . LEU B 1 722 ? 143.722 135.117 110.962 1.00 41.72  ?  711 LEU B O   1 
ATOM   10807 C  CB  . LEU B 1 722 ? 145.825 134.777 108.318 1.00 41.72  ?  711 LEU B CB  1 
ATOM   10808 C  CG  . LEU B 1 722 ? 147.325 134.814 108.051 1.00 41.72  ?  711 LEU B CG  1 
ATOM   10809 C  CD1 . LEU B 1 722 ? 147.635 135.908 107.072 1.00 41.72  ?  711 LEU B CD1 1 
ATOM   10810 C  CD2 . LEU B 1 722 ? 148.093 135.020 109.327 1.00 41.72  ?  711 LEU B CD2 1 
ATOM   10811 N  N   . THR B 1 723 ? 142.967 134.087 109.123 1.00 39.55  ?  712 THR B N   1 
ATOM   10812 C  CA  . THR B 1 723 ? 141.590 134.520 109.285 1.00 39.55  ?  712 THR B CA  1 
ATOM   10813 C  C   . THR B 1 723 ? 140.670 133.320 109.137 1.00 39.55  ?  712 THR B C   1 
ATOM   10814 O  O   . THR B 1 723 ? 141.110 132.214 108.836 1.00 39.55  ?  712 THR B O   1 
ATOM   10815 C  CB  . THR B 1 723 ? 141.229 135.615 108.271 1.00 39.55  ?  712 THR B CB  1 
ATOM   10816 O  OG1 . THR B 1 723 ? 141.494 135.157 106.945 1.00 39.55  ?  712 THR B OG1 1 
ATOM   10817 C  CG2 . THR B 1 723 ? 142.039 136.856 108.520 1.00 39.55  ?  712 THR B CG2 1 
ATOM   10818 N  N   . ILE B 1 724 ? 139.375 133.544 109.360 1.00 36.94  ?  713 ILE B N   1 
ATOM   10819 C  CA  . ILE B 1 724 ? 138.391 132.490 109.151 1.00 36.94  ?  713 ILE B CA  1 
ATOM   10820 C  C   . ILE B 1 724 ? 138.339 132.093 107.688 1.00 36.94  ?  713 ILE B C   1 
ATOM   10821 O  O   . ILE B 1 724 ? 138.193 130.914 107.360 1.00 36.94  ?  713 ILE B O   1 
ATOM   10822 C  CB  . ILE B 1 724 ? 137.004 132.933 109.649 1.00 36.94  ?  713 ILE B CB  1 
ATOM   10823 C  CG1 . ILE B 1 724 ? 137.044 133.313 111.119 1.00 36.94  ?  713 ILE B CG1 1 
ATOM   10824 C  CG2 . ILE B 1 724 ? 135.987 131.844 109.438 1.00 36.94  ?  713 ILE B CG2 1 
ATOM   10825 C  CD1 . ILE B 1 724 ? 135.769 133.902 111.610 1.00 36.94  ?  713 ILE B CD1 1 
ATOM   10826 N  N   . HIS B 1 725 ? 138.451 133.060 106.784 1.00 36.55  ?  714 HIS B N   1 
ATOM   10827 C  CA  . HIS B 1 725 ? 138.347 132.747 105.369 1.00 36.55  ?  714 HIS B CA  1 
ATOM   10828 C  C   . HIS B 1 725 ? 139.558 131.977 104.870 1.00 36.55  ?  714 HIS B C   1 
ATOM   10829 O  O   . HIS B 1 725 ? 139.422 131.135 103.981 1.00 36.55  ?  714 HIS B O   1 
ATOM   10830 C  CB  . HIS B 1 725 ? 138.147 134.024 104.563 1.00 36.55  ?  714 HIS B CB  1 
ATOM   10831 C  CG  . HIS B 1 725 ? 137.501 133.795 103.238 1.00 36.55  ?  714 HIS B CG  1 
ATOM   10832 N  ND1 . HIS B 1 725 ? 138.037 134.255 102.060 1.00 36.55  ?  714 HIS B ND1 1 
ATOM   10833 C  CD2 . HIS B 1 725 ? 136.372 133.132 102.903 1.00 36.55  ?  714 HIS B CD2 1 
ATOM   10834 C  CE1 . HIS B 1 725 ? 137.262 133.894 101.057 1.00 36.55  ?  714 HIS B CE1 1 
ATOM   10835 N  NE2 . HIS B 1 725 ? 136.243 133.213 101.542 1.00 36.55  ?  714 HIS B NE2 1 
ATOM   10836 N  N   . ASP B 1 726 ? 140.737 132.233 105.431 1.00 39.70  ?  715 ASP B N   1 
ATOM   10837 C  CA  . ASP B 1 726 ? 141.908 131.428 105.109 1.00 39.70  ?  715 ASP B CA  1 
ATOM   10838 C  C   . ASP B 1 726 ? 141.670 129.966 105.443 1.00 39.70  ?  715 ASP B C   1 
ATOM   10839 O  O   . ASP B 1 726 ? 141.931 129.078 104.626 1.00 39.70  ?  715 ASP B O   1 
ATOM   10840 C  CB  . ASP B 1 726 ? 143.129 131.941 105.870 1.00 39.70  ?  715 ASP B CB  1 
ATOM   10841 C  CG  . ASP B 1 726 ? 143.667 133.225 105.313 1.00 39.70  ?  715 ASP B CG  1 
ATOM   10842 O  OD1 . ASP B 1 726 ? 143.280 134.292 105.816 1.00 39.70  ?  715 ASP B OD1 1 
ATOM   10843 O  OD2 . ASP B 1 726 ? 144.482 133.177 104.378 1.00 39.70  -1 715 ASP B OD2 1 
ATOM   10844 N  N   . ALA B 1 727 ? 141.174 129.699 106.648 1.00 39.36  ?  716 ALA B N   1 
ATOM   10845 C  CA  . ALA B 1 727 ? 140.910 128.328 107.058 1.00 39.36  ?  716 ALA B CA  1 
ATOM   10846 C  C   . ALA B 1 727 ? 139.811 127.701 106.217 1.00 39.36  ?  716 ALA B C   1 
ATOM   10847 O  O   . ALA B 1 727 ? 139.910 126.534 105.841 1.00 39.36  ?  716 ALA B O   1 
ATOM   10848 C  CB  . ALA B 1 727 ? 140.543 128.287 108.535 1.00 39.36  ?  716 ALA B CB  1 
ATOM   10849 N  N   . VAL B 1 728 ? 138.767 128.461 105.895 1.00 38.70  ?  717 VAL B N   1 
ATOM   10850 C  CA  . VAL B 1 728 ? 137.673 127.917 105.100 1.00 38.70  ?  717 VAL B CA  1 
ATOM   10851 C  C   . VAL B 1 728 ? 138.153 127.554 103.703 1.00 38.70  ?  717 VAL B C   1 
ATOM   10852 O  O   . VAL B 1 728 ? 137.812 126.493 103.178 1.00 38.70  ?  717 VAL B O   1 
ATOM   10853 C  CB  . VAL B 1 728 ? 136.496 128.908 105.062 1.00 38.70  ?  717 VAL B CB  1 
ATOM   10854 C  CG1 . VAL B 1 728 ? 135.528 128.539 103.975 1.00 38.70  ?  717 VAL B CG1 1 
ATOM   10855 C  CG2 . VAL B 1 728 ? 135.790 128.929 106.385 1.00 38.70  ?  717 VAL B CG2 1 
ATOM   10856 N  N   . LEU B 1 729 ? 138.959 128.415 103.084 1.00 40.61  ?  718 LEU B N   1 
ATOM   10857 C  CA  . LEU B 1 729 ? 139.449 128.125 101.742 1.00 40.61  ?  718 LEU B CA  1 
ATOM   10858 C  C   . LEU B 1 729 ? 140.426 126.962 101.753 1.00 40.61  ?  718 LEU B C   1 
ATOM   10859 O  O   . LEU B 1 729 ? 140.415 126.131 100.839 1.00 40.61  ?  718 LEU B O   1 
ATOM   10860 C  CB  . LEU B 1 729 ? 140.096 129.366 101.141 1.00 40.61  ?  718 LEU B CB  1 
ATOM   10861 C  CG  . LEU B 1 729 ? 139.147 130.516 100.828 1.00 40.61  ?  718 LEU B CG  1 
ATOM   10862 C  CD1 . LEU B 1 729 ? 139.921 131.701 100.328 1.00 40.61  ?  718 LEU B CD1 1 
ATOM   10863 C  CD2 . LEU B 1 729 ? 138.117 130.092 99.824  1.00 40.61  ?  718 LEU B CD2 1 
ATOM   10864 N  N   . HIS B 1 730 ? 141.265 126.873 102.784 1.00 43.27  ?  719 HIS B N   1 
ATOM   10865 C  CA  . HIS B 1 730 ? 142.142 125.720 102.929 1.00 43.27  ?  719 HIS B CA  1 
ATOM   10866 C  C   . HIS B 1 730 ? 141.343 124.431 103.061 1.00 43.27  ?  719 HIS B C   1 
ATOM   10867 O  O   . HIS B 1 730 ? 141.667 123.422 102.426 1.00 43.27  ?  719 HIS B O   1 
ATOM   10868 C  CB  . HIS B 1 730 ? 143.052 125.922 104.137 1.00 43.27  ?  719 HIS B CB  1 
ATOM   10869 C  CG  . HIS B 1 730 ? 143.920 124.748 104.448 1.00 43.27  ?  719 HIS B CG  1 
ATOM   10870 N  ND1 . HIS B 1 730 ? 145.127 124.533 103.824 1.00 43.27  ?  719 HIS B ND1 1 
ATOM   10871 C  CD2 . HIS B 1 730 ? 143.762 123.728 105.321 1.00 43.27  ?  719 HIS B CD2 1 
ATOM   10872 C  CE1 . HIS B 1 730 ? 145.673 123.430 104.297 1.00 43.27  ?  719 HIS B CE1 1 
ATOM   10873 N  NE2 . HIS B 1 730 ? 144.864 122.921 105.205 1.00 43.27  ?  719 HIS B NE2 1 
ATOM   10874 N  N   . ILE B 1 731 ? 140.288 124.453 103.874 1.00 45.01  ?  720 ILE B N   1 
ATOM   10875 C  CA  . ILE B 1 731 ? 139.437 123.281 104.044 1.00 45.01  ?  720 ILE B CA  1 
ATOM   10876 C  C   . ILE B 1 731 ? 138.791 122.895 102.725 1.00 45.01  ?  720 ILE B C   1 
ATOM   10877 O  O   . ILE B 1 731 ? 138.721 121.716 102.373 1.00 45.01  ?  720 ILE B O   1 
ATOM   10878 C  CB  . ILE B 1 731 ? 138.375 123.546 105.124 1.00 45.01  ?  720 ILE B CB  1 
ATOM   10879 C  CG1 . ILE B 1 731 ? 139.007 123.572 106.508 1.00 45.01  ?  720 ILE B CG1 1 
ATOM   10880 C  CG2 . ILE B 1 731 ? 137.286 122.519 105.051 1.00 45.01  ?  720 ILE B CG2 1 
ATOM   10881 C  CD1 . ILE B 1 731 ? 138.236 124.374 107.491 1.00 45.01  ?  720 ILE B CD1 1 
ATOM   10882 N  N   . LEU B 1 732 ? 138.291 123.881 101.984 1.00 49.99  ?  721 LEU B N   1 
ATOM   10883 C  CA  . LEU B 1 732 ? 137.623 123.578 100.726 1.00 49.99  ?  721 LEU B CA  1 
ATOM   10884 C  C   . LEU B 1 732 ? 138.588 122.997 99.710  1.00 49.99  ?  721 LEU B C   1 
ATOM   10885 O  O   . LEU B 1 732 ? 138.213 122.123 98.929  1.00 49.99  ?  721 LEU B O   1 
ATOM   10886 C  CB  . LEU B 1 732 ? 136.953 124.823 100.162 1.00 49.99  ?  721 LEU B CB  1 
ATOM   10887 C  CG  . LEU B 1 732 ? 135.809 125.393 100.991 1.00 49.99  ?  721 LEU B CG  1 
ATOM   10888 C  CD1 . LEU B 1 732 ? 135.281 126.653 100.356 1.00 49.99  ?  721 LEU B CD1 1 
ATOM   10889 C  CD2 . LEU B 1 732 ? 134.719 124.373 101.152 1.00 49.99  ?  721 LEU B CD2 1 
ATOM   10890 N  N   . MET B 1 733 ? 139.834 123.454 99.704  1.00 56.38  ?  722 MET B N   1 
ATOM   10891 C  CA  . MET B 1 733 ? 140.806 122.862 98.793  1.00 56.38  ?  722 MET B CA  1 
ATOM   10892 C  C   . MET B 1 733 ? 141.148 121.436 99.207  1.00 56.38  ?  722 MET B C   1 
ATOM   10893 O  O   . MET B 1 733 ? 141.273 120.542 98.360  1.00 56.38  ?  722 MET B O   1 
ATOM   10894 C  CB  . MET B 1 733 ? 142.048 123.743 98.726  1.00 56.38  ?  722 MET B CB  1 
ATOM   10895 C  CG  . MET B 1 733 ? 141.733 125.124 98.177  1.00 56.38  ?  722 MET B CG  1 
ATOM   10896 S  SD  . MET B 1 733 ? 142.998 126.403 98.347  1.00 56.38  ?  722 MET B SD  1 
ATOM   10897 C  CE  . MET B 1 733 ? 143.925 125.854 99.773  1.00 56.38  ?  722 MET B CE  1 
ATOM   10898 N  N   . LYS B 1 734 ? 141.288 121.199 100.512 1.00 60.38  ?  723 LYS B N   1 
ATOM   10899 C  CA  . LYS B 1 734 ? 141.499 119.840 101.002 1.00 60.38  ?  723 LYS B CA  1 
ATOM   10900 C  C   . LYS B 1 734 ? 140.361 118.915 100.592 1.00 60.38  ?  723 LYS B C   1 
ATOM   10901 O  O   . LYS B 1 734 ? 140.590 117.769 100.193 1.00 60.38  ?  723 LYS B O   1 
ATOM   10902 C  CB  . LYS B 1 734 ? 141.640 119.854 102.518 1.00 60.38  ?  723 LYS B CB  1 
ATOM   10903 C  CG  . LYS B 1 734 ? 143.024 120.151 103.004 1.00 60.38  ?  723 LYS B CG  1 
ATOM   10904 C  CD  . LYS B 1 734 ? 143.160 119.793 104.462 1.00 60.38  ?  723 LYS B CD  1 
ATOM   10905 C  CE  . LYS B 1 734 ? 142.748 118.362 104.703 1.00 60.38  ?  723 LYS B CE  1 
ATOM   10906 N  NZ  . LYS B 1 734 ? 143.105 117.907 106.067 1.00 60.38  1  723 LYS B NZ  1 
ATOM   10907 N  N   . LYS B 1 735 ? 139.124 119.396 100.675 1.00 65.83  ?  724 LYS B N   1 
ATOM   10908 C  CA  . LYS B 1 735 ? 137.991 118.540 100.343 1.00 65.83  ?  724 LYS B CA  1 
ATOM   10909 C  C   . LYS B 1 735 ? 137.845 118.382 98.837  1.00 65.83  ?  724 LYS B C   1 
ATOM   10910 O  O   . LYS B 1 735 ? 137.392 117.339 98.356  1.00 65.83  ?  724 LYS B O   1 
ATOM   10911 C  CB  . LYS B 1 735 ? 136.715 119.090 100.967 1.00 65.83  ?  724 LYS B CB  1 
ATOM   10912 C  CG  . LYS B 1 735 ? 136.753 119.078 102.472 1.00 65.83  ?  724 LYS B CG  1 
ATOM   10913 C  CD  . LYS B 1 735 ? 137.384 117.800 102.992 1.00 65.83  ?  724 LYS B CD  1 
ATOM   10914 C  CE  . LYS B 1 735 ? 138.122 118.043 104.295 1.00 65.83  ?  724 LYS B CE  1 
ATOM   10915 N  NZ  . LYS B 1 735 ? 138.510 116.784 104.986 1.00 65.83  1  724 LYS B NZ  1 
ATOM   10916 N  N   . ASP B 1 736 ? 138.242 119.396 98.068  1.00 73.58  ?  725 ASP B N   1 
ATOM   10917 C  CA  . ASP B 1 736 ? 138.322 119.213 96.626  1.00 73.58  ?  725 ASP B CA  1 
ATOM   10918 C  C   . ASP B 1 736 ? 139.307 118.115 96.271  1.00 73.58  ?  725 ASP B C   1 
ATOM   10919 O  O   . ASP B 1 736 ? 139.045 117.310 95.372  1.00 73.58  ?  725 ASP B O   1 
ATOM   10920 C  CB  . ASP B 1 736 ? 138.725 120.511 95.933  1.00 73.58  ?  725 ASP B CB  1 
ATOM   10921 C  CG  . ASP B 1 736 ? 137.553 121.446 95.706  1.00 73.58  ?  725 ASP B CG  1 
ATOM   10922 O  OD1 . ASP B 1 736 ? 137.633 122.625 96.110  1.00 73.58  ?  725 ASP B OD1 1 
ATOM   10923 O  OD2 . ASP B 1 736 ? 136.551 121.004 95.112  1.00 73.58  -1 725 ASP B OD2 1 
HETATM 10924 CL CL  . CL  C 2 .   ? 143.178 111.577 150.993 1.00 30.00  ?  801 CL  A CL  1 
HETATM 10925 C  C1  . LPE D 3 .   ? 143.661 98.686  148.244 1.00 20.00  ?  802 LPE A C1  1 
HETATM 10926 O  O1  . LPE D 3 .   ? 142.512 97.942  148.624 1.00 20.00  ?  802 LPE A O1  1 
HETATM 10927 C  C2  . LPE D 3 .   ? 143.692 98.798  146.728 1.00 20.00  ?  802 LPE A C2  1 
HETATM 10928 O  O2H . LPE D 3 .   ? 142.543 99.514  146.271 1.00 20.00  ?  802 LPE A O2H 1 
HETATM 10929 C  C3  . LPE D 3 .   ? 144.954 99.533  146.294 1.00 20.00  ?  802 LPE A C3  1 
HETATM 10930 C  C11 . LPE D 3 .   ? 142.685 97.292  149.873 1.00 20.00  ?  802 LPE A C11 1 
HETATM 10931 C  C12 . LPE D 3 .   ? 141.585 97.727  150.825 1.00 20.00  ?  802 LPE A C12 1 
HETATM 10932 O  O3  . LPE D 3 .   ? 144.760 100.930 146.456 1.00 20.00  ?  802 LPE A O3  1 
HETATM 10933 P  P   . LPE D 3 .   ? 145.289 101.924 145.319 1.00 20.00  ?  802 LPE A P   1 
HETATM 10934 O  O31 . LPE D 3 .   ? 145.738 101.071 144.164 1.00 20.00  -1 802 LPE A O31 1 
HETATM 10935 O  O32 . LPE D 3 .   ? 144.249 103.001 145.098 1.00 20.00  ?  802 LPE A O32 1 
HETATM 10936 O  O33 . LPE D 3 .   ? 146.611 102.592 145.949 1.00 20.00  ?  802 LPE A O33 1 
HETATM 10937 C  C31 . LPE D 3 .   ? 146.938 103.941 145.632 1.00 20.00  ?  802 LPE A C31 1 
HETATM 10938 C  C32 . LPE D 3 .   ? 147.574 104.629 146.831 1.00 20.00  ?  802 LPE A C32 1 
HETATM 10939 N  N   . LPE D 3 .   ? 147.480 106.087 146.701 1.00 20.00  ?  802 LPE A N   1 
HETATM 10940 C  C1N . LPE D 3 .   ? 148.672 106.547 145.991 1.00 20.00  ?  802 LPE A C1N 1 
HETATM 10941 C  C2N . LPE D 3 .   ? 146.283 106.476 145.937 1.00 20.00  ?  802 LPE A C2N 1 
HETATM 10942 C  C3N . LPE D 3 .   ? 147.437 106.714 148.028 1.00 20.00  ?  802 LPE A C3N 1 
HETATM 10943 C  C13 . LPE D 3 .   ? 141.670 96.935  152.120 1.00 20.00  ?  802 LPE A C13 1 
HETATM 10944 C  C14 . LPE D 3 .   ? 140.844 95.663  152.029 1.00 20.00  ?  802 LPE A C14 1 
HETATM 10945 C  C15 . LPE D 3 .   ? 141.550 94.505  152.715 1.00 20.00  ?  802 LPE A C15 1 
HETATM 10946 C  C16 . LPE D 3 .   ? 140.566 93.694  153.543 1.00 20.00  ?  802 LPE A C16 1 
HETATM 10947 C  C17 . LPE D 3 .   ? 140.977 92.232  153.632 1.00 20.00  ?  802 LPE A C17 1 
HETATM 10948 C  C18 . LPE D 3 .   ? 140.260 91.410  152.570 1.00 20.00  ?  802 LPE A C18 1 
HETATM 10949 C  C10 . I2U E 4 .   ? 144.654 104.177 153.811 1.00 20.00  ?  803 I2U A C10 1 
HETATM 10950 C  C13 . I2U E 4 .   ? 143.910 100.914 152.390 1.00 20.00  ?  803 I2U A C13 1 
HETATM 10951 C  C15 . I2U E 4 .   ? 143.441 100.676 154.697 1.00 20.00  ?  803 I2U A C15 1 
HETATM 10952 C  C17 . I2U E 4 .   ? 144.880 102.957 150.352 1.00 20.00  ?  803 I2U A C17 1 
HETATM 10953 C  C20 . I2U E 4 .   ? 144.411 105.246 158.436 1.00 20.00  ?  803 I2U A C20 1 
HETATM 10954 C  C21 . I2U E 4 .   ? 144.781 106.537 158.358 1.00 20.00  ?  803 I2U A C21 1 
HETATM 10955 C  C8  . I2U E 4 .   ? 144.230 102.826 153.934 1.00 20.00  ?  803 I2U A C8  1 
HETATM 10956 C  C9  . I2U E 4 .   ? 144.272 102.228 152.643 1.00 20.00  ?  803 I2U A C9  1 
HETATM 10957 C  C11 . I2U E 4 .   ? 144.927 104.323 152.483 1.00 20.00  ?  803 I2U A C11 1 
HETATM 10958 C  C12 . I2U E 4 .   ? 143.795 101.998 154.970 1.00 20.00  ?  803 I2U A C12 1 
HETATM 10959 C  C14 . I2U E 4 .   ? 144.859 105.304 154.721 1.00 20.00  ?  803 I2U A C14 1 
HETATM 10960 C  C16 . I2U E 4 .   ? 143.489 100.121 153.438 1.00 20.00  ?  803 I2U A C16 1 
HETATM 10961 C  C18 . I2U E 4 .   ? 144.723 105.421 156.167 1.00 20.00  ?  803 I2U A C18 1 
HETATM 10962 C  C19 . I2U E 4 .   ? 144.370 104.600 157.188 1.00 20.00  ?  803 I2U A C19 1 
HETATM 10963 N  N6  . I2U E 4 .   ? 144.693 103.156 151.758 1.00 20.00  ?  803 I2U A N6  1 
HETATM 10964 N  N7  . I2U E 4 .   ? 144.604 101.778 149.853 1.00 20.00  ?  803 I2U A N7  1 
HETATM 10965 O  O3  . I2U E 4 .   ? 145.373 105.406 151.831 1.00 20.00  ?  803 I2U A O3  1 
HETATM 10966 O  O4  . I2U E 4 .   ? 145.232 106.340 154.202 1.00 20.00  ?  803 I2U A O4  1 
HETATM 10967 O  O5  . I2U E 4 .   ? 145.280 103.863 149.641 1.00 20.00  ?  803 I2U A O5  1 
HETATM 10968 S  S2  . I2U E 4 .   ? 145.113 107.009 156.742 1.00 20.00  ?  803 I2U A S2  1 
HETATM 10969 CL CL1 . I2U E 4 .   ? 142.904 99.626  155.900 1.00 20.00  ?  803 I2U A CL1 1 
HETATM 10970 CL CL  . CL  F 2 .   ? 136.364 168.056 151.073 1.00 30.00  ?  801 CL  B CL  1 
HETATM 10971 C  C1  . LPE G 3 .   ? 135.896 180.606 148.513 1.00 20.00  ?  802 LPE B C1  1 
HETATM 10972 O  O1  . LPE G 3 .   ? 136.570 181.748 149.042 1.00 20.00  ?  802 LPE B O1  1 
HETATM 10973 C  C2  . LPE G 3 .   ? 135.494 180.846 147.066 1.00 20.00  ?  802 LPE B C2  1 
HETATM 10974 O  O2H . LPE G 3 .   ? 136.601 180.527 146.222 1.00 20.00  ?  802 LPE B O2H 1 
HETATM 10975 C  C3  . LPE G 3 .   ? 134.323 179.951 146.684 1.00 20.00  ?  802 LPE B C3  1 
HETATM 10976 C  C11 . LPE G 3 .   ? 137.646 181.337 149.877 1.00 20.00  ?  802 LPE B C11 1 
HETATM 10977 C  C12 . LPE G 3 .   ? 137.595 182.013 151.238 1.00 20.00  ?  802 LPE B C12 1 
HETATM 10978 O  O3  . LPE G 3 .   ? 134.800 178.622 146.525 1.00 20.00  ?  802 LPE B O3  1 
HETATM 10979 P  P   . LPE G 3 .   ? 134.199 177.677 145.378 1.00 20.00  ?  802 LPE B P   1 
HETATM 10980 O  O31 . LPE G 3 .   ? 133.665 178.579 144.296 1.00 20.00  -1 802 LPE B O31 1 
HETATM 10981 O  O32 . LPE G 3 .   ? 135.240 176.634 145.043 1.00 20.00  ?  802 LPE B O32 1 
HETATM 10982 O  O33 . LPE G 3 .   ? 132.936 176.953 146.064 1.00 20.00  ?  802 LPE B O33 1 
HETATM 10983 C  C31 . LPE G 3 .   ? 132.734 175.559 145.856 1.00 20.00  ?  802 LPE B C31 1 
HETATM 10984 C  C32 . LPE G 3 .   ? 131.960 174.960 147.022 1.00 20.00  ?  802 LPE B C32 1 
HETATM 10985 N  N   . LPE G 3 .   ? 132.016 173.493 146.977 1.00 20.00  ?  802 LPE B N   1 
HETATM 10986 C  C1N . LPE G 3 .   ? 130.881 173.018 146.184 1.00 20.00  ?  802 LPE B C1N 1 
HETATM 10987 C  C2N . LPE G 3 .   ? 133.266 173.026 146.358 1.00 20.00  ?  802 LPE B C2N 1 
HETATM 10988 C  C3N . LPE G 3 .   ? 131.923 172.943 148.334 1.00 20.00  ?  802 LPE B C3N 1 
HETATM 10989 C  C13 . LPE G 3 .   ? 138.041 183.459 151.146 1.00 20.00  ?  802 LPE B C13 1 
HETATM 10990 C  C14 . LPE G 3 .   ? 138.326 184.032 152.524 1.00 20.00  ?  802 LPE B C14 1 
HETATM 10991 C  C15 . LPE G 3 .   ? 138.640 185.514 152.397 1.00 20.00  ?  802 LPE B C15 1 
HETATM 10992 C  C16 . LPE G 3 .   ? 138.551 186.222 153.740 1.00 20.00  ?  802 LPE B C16 1 
HETATM 10993 C  C17 . LPE G 3 .   ? 138.616 187.730 153.549 1.00 20.00  ?  802 LPE B C17 1 
HETATM 10994 C  C18 . LPE G 3 .   ? 139.769 188.111 152.631 1.00 20.00  ?  802 LPE B C18 1 
HETATM 10995 C  C10 . I2U H 4 .   ? 134.868 175.234 153.583 1.00 20.00  ?  803 I2U B C10 1 
HETATM 10996 C  C13 . I2U H 4 .   ? 135.552 178.480 152.057 1.00 20.00  ?  803 I2U B C13 1 
HETATM 10997 C  C15 . I2U H 4 .   ? 136.054 178.808 154.373 1.00 20.00  ?  803 I2U B C15 1 
HETATM 10998 C  C17 . I2U H 4 .   ? 134.531 176.204 150.039 1.00 20.00  ?  803 I2U B C17 1 
HETATM 10999 C  C20 . I2U H 4 .   ? 135.217 174.612 158.280 1.00 20.00  ?  803 I2U B C20 1 
HETATM 11000 C  C21 . I2U H 4 .   ? 134.868 173.301 158.344 1.00 20.00  ?  803 I2U B C21 1 
HETATM 11001 C  C8  . I2U H 4 .   ? 135.273 176.608 153.646 1.00 20.00  ?  803 I2U B C8  1 
HETATM 11002 C  C9  . I2U H 4 .   ? 135.206 177.153 152.324 1.00 20.00  ?  803 I2U B C9  1 
HETATM 11003 C  C11 . I2U H 4 .   ? 134.572 175.017 152.263 1.00 20.00  ?  803 I2U B C11 1 
HETATM 11004 C  C12 . I2U H 4 .   ? 135.713 177.479 154.664 1.00 20.00  ?  803 I2U B C12 1 
HETATM 11005 C  C14 . I2U H 4 .   ? 134.704 174.165 154.580 1.00 20.00  ?  803 I2U B C14 1 
HETATM 11006 C  C16 . I2U H 4 .   ? 135.979 179.315 153.084 1.00 20.00  ?  803 I2U B C16 1 
HETATM 11007 C  C18 . I2U H 4 .   ? 134.868 174.202 156.031 1.00 20.00  ?  803 I2U B C18 1 
HETATM 11008 C  C19 . I2U H 4 .   ? 135.225 175.134 156.962 1.00 20.00  ?  803 I2U B C19 1 
HETATM 11009 N  N6  . I2U H 4 .   ? 134.776 176.158 151.471 1.00 20.00  ?  803 I2U B N6  1 
HETATM 11010 N  N7  . I2U H 4 .   ? 134.728 177.294 149.322 1.00 20.00  ?  803 I2U B N7  1 
HETATM 11011 O  O3  . I2U H 4 .   ? 134.134 173.886 151.679 1.00 20.00  ?  803 I2U B O3  1 
HETATM 11012 O  O4  . I2U H 4 .   ? 134.353 173.064 154.174 1.00 20.00  ?  803 I2U B O4  1 
HETATM 11013 O  O5  . I2U H 4 .   ? 134.141 175.192 149.480 1.00 20.00  ?  803 I2U B O5  1 
HETATM 11014 S  S2  . I2U H 4 .   ? 134.516 172.666 156.776 1.00 20.00  ?  803 I2U B S2  1 
HETATM 11015 CL CL1 . I2U H 4 .   ? 136.591 179.888 155.575 1.00 20.00  ?  803 I2U B CL1 1 
# 
