data_8X0D
# 
_entry.id   8X0D 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8X0D         pdb_00008x0d 10.2210/pdb8x0d/pdb 
WWPDB D_1300042380 ?            ?                   
EMDB  EMD-37975    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-06 
2 'Structure model' 1 1 2024-11-27 
3 'Structure model' 1 2 2025-01-29 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 3 'Structure model' 'Data collection'     
3 3 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' em_admin        
2 3 'Structure model' citation        
3 3 'Structure model' citation_author 
4 3 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_em_admin.last_update'             
2  3 'Structure model' '_citation.country'                 
3  3 'Structure model' '_citation.journal_abbrev'          
4  3 'Structure model' '_citation.journal_id_CSD'          
5  3 'Structure model' '_citation.journal_id_ISSN'         
6  3 'Structure model' '_citation.journal_volume'          
7  3 'Structure model' '_citation.page_first'              
8  3 'Structure model' '_citation.page_last'               
9  3 'Structure model' '_citation.pdbx_database_id_DOI'    
10 3 'Structure model' '_citation.pdbx_database_id_PubMed' 
11 3 'Structure model' '_citation.title'                   
12 3 'Structure model' '_citation.year'                    
13 3 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8X0D 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-04 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'Conformer 1 of the same data set'                                                                 EMD-37974 
'other EM volume'      
EMDB 'Receptor with same ligand collected with K3'                                                      EMD-37973 
'other EM volume'      
EMDB 'W785A mutant of the receptor with same ligand'                                                    EMD-37976 
'other EM volume'      
EMDB 'Receptor with different PAM'                                                                      EMD-37977 
'other EM volume'      
EMDB 'Receptor with different PAM'                                                                      EMD-37978 
'other EM volume'      
EMDB 'Human FL Metabotropic glutamate receptor 5, mGlu5-5M with quisqualate and VU0424465, conformer 2' EMD-37975 
'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              vkumar@ncbs.res.in 
_pdbx_contact_author.name_first         Vinothkumar 
_pdbx_contact_author.name_last          'Ragunath Kutti' 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6746-5684 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lebon, G.'         1 0000-0003-1162-5148 
'Cannone, G.'       2 0000-0002-4381-2522 
'Vinothkumar, K.R.' 3 0000-0002-6746-5684 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                619 
_citation.page_last                 619 
_citation.title                     'Conformational diversity in class C GPCR positive allosteric modulation.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-55439-9 
_citation.pdbx_database_id_PubMed   39805839 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Cannone, G.'     1  ?                   
primary 'Berto, L.'       2  ?                   
primary 'Malhaire, F.'    3  ?                   
primary 'Ferguson, G.'    4  0000-0003-2551-5994 
primary 'Fouillen, A.'    5  0000-0002-0326-9932 
primary 'Balor, S.'       6  ?                   
primary 'Font-Ingles, J.' 7  ?                   
primary 'Llebaria, A.'    8  0000-0002-8200-4827 
primary 'Goudet, C.'      9  0000-0002-8255-3535 
primary 'Kotecha, A.'     10 0000-0002-4480-5439 
primary 'K R, V.'         11 0000-0002-6746-5684 
primary 'Lebon, G.'       12 0000-0003-1162-5148 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Metabotropic glutamate receptor 5'                                  93691.492 2 ? 
T742A,S753A,T777A,I799A,A813L,N445A,H350L ? 
;The construct has tags and protease cleavage site at its N-term (DYKDDDDKHHHHHHHHHHLEVLFQGP) and when compared to uniprot it starts at 21 and ends at 856. For CryoEM, the tag is cleaved and the protein used for experiment starts at QSSE but residues starting RR have been modeled. There are 5 thermostabilising mutations (T742A, S753A, T777A, I799A, A813L). Residue N445 is mutated to remove glycosylation. An additional mutation H350L is engineered for a nanobody to bind. Each monomer has one sugar modeled and 10 disulfide bonds.
;
2 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose                             221.208   2 ? ? ? ? 
3 non-polymer syn '(S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID' 189.126   2 ? ? ? ? 
4 non-polymer syn VU0424465                                                            326.365   2 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;QSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCW
HSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLS
DKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKL
LKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDY
YLKLRPETNLRNPWFQEFWQHRFQCRLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP
GYAGLCDAMKPIDGRKLLESLMKTAFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDDDEVW
SKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEP
IAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYS
ALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVYLICNTTNLGV
VAPLGYNGLLILACTFYAFKTRNVPANFNEAKYIAFAMYTTCIIWLAFVPIYFGSNYKAITMCFSVSLSATVLLGCMFVP
KVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;QSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCW
HSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLS
DKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKL
LKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDY
YLKLRPETNLRNPWFQEFWQHRFQCRLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP
GYAGLCDAMKPIDGRKLLESLMKTAFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDDDEVW
SKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEP
IAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYS
ALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVYLICNTTNLGV
VAPLGYNGLLILACTFYAFKTRNVPANFNEAKYIAFAMYTTCIIWLAFVPIYFGSNYKAITMCFSVSLSATVLLGCMFVP
KVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAA
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 2-acetamido-2-deoxy-beta-D-glucopyranose                             NAG 
3 '(S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID' QUS 
4 VU0424465                                                            XQT 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLN n 
1 2   SER n 
1 3   SER n 
1 4   GLU n 
1 5   ARG n 
1 6   ARG n 
1 7   VAL n 
1 8   VAL n 
1 9   ALA n 
1 10  HIS n 
1 11  MET n 
1 12  PRO n 
1 13  GLY n 
1 14  ASP n 
1 15  ILE n 
1 16  ILE n 
1 17  ILE n 
1 18  GLY n 
1 19  ALA n 
1 20  LEU n 
1 21  PHE n 
1 22  SER n 
1 23  VAL n 
1 24  HIS n 
1 25  HIS n 
1 26  GLN n 
1 27  PRO n 
1 28  THR n 
1 29  VAL n 
1 30  ASP n 
1 31  LYS n 
1 32  VAL n 
1 33  HIS n 
1 34  GLU n 
1 35  ARG n 
1 36  LYS n 
1 37  CYS n 
1 38  GLY n 
1 39  ALA n 
1 40  VAL n 
1 41  ARG n 
1 42  GLU n 
1 43  GLN n 
1 44  TYR n 
1 45  GLY n 
1 46  ILE n 
1 47  GLN n 
1 48  ARG n 
1 49  VAL n 
1 50  GLU n 
1 51  ALA n 
1 52  MET n 
1 53  LEU n 
1 54  HIS n 
1 55  THR n 
1 56  LEU n 
1 57  GLU n 
1 58  ARG n 
1 59  ILE n 
1 60  ASN n 
1 61  SER n 
1 62  ASP n 
1 63  PRO n 
1 64  THR n 
1 65  LEU n 
1 66  LEU n 
1 67  PRO n 
1 68  ASN n 
1 69  ILE n 
1 70  THR n 
1 71  LEU n 
1 72  GLY n 
1 73  CYS n 
1 74  GLU n 
1 75  ILE n 
1 76  ARG n 
1 77  ASP n 
1 78  SER n 
1 79  CYS n 
1 80  TRP n 
1 81  HIS n 
1 82  SER n 
1 83  ALA n 
1 84  VAL n 
1 85  ALA n 
1 86  LEU n 
1 87  GLU n 
1 88  GLN n 
1 89  SER n 
1 90  ILE n 
1 91  GLU n 
1 92  PHE n 
1 93  ILE n 
1 94  ARG n 
1 95  ASP n 
1 96  SER n 
1 97  LEU n 
1 98  ILE n 
1 99  SER n 
1 100 SER n 
1 101 GLU n 
1 102 GLU n 
1 103 GLU n 
1 104 GLU n 
1 105 GLY n 
1 106 LEU n 
1 107 VAL n 
1 108 ARG n 
1 109 CYS n 
1 110 VAL n 
1 111 ASP n 
1 112 GLY n 
1 113 SER n 
1 114 SER n 
1 115 SER n 
1 116 SER n 
1 117 PHE n 
1 118 ARG n 
1 119 SER n 
1 120 LYS n 
1 121 LYS n 
1 122 PRO n 
1 123 ILE n 
1 124 VAL n 
1 125 GLY n 
1 126 VAL n 
1 127 ILE n 
1 128 GLY n 
1 129 PRO n 
1 130 GLY n 
1 131 SER n 
1 132 SER n 
1 133 SER n 
1 134 VAL n 
1 135 ALA n 
1 136 ILE n 
1 137 GLN n 
1 138 VAL n 
1 139 GLN n 
1 140 ASN n 
1 141 LEU n 
1 142 LEU n 
1 143 GLN n 
1 144 LEU n 
1 145 PHE n 
1 146 ASN n 
1 147 ILE n 
1 148 PRO n 
1 149 GLN n 
1 150 ILE n 
1 151 ALA n 
1 152 TYR n 
1 153 SER n 
1 154 ALA n 
1 155 THR n 
1 156 SER n 
1 157 MET n 
1 158 ASP n 
1 159 LEU n 
1 160 SER n 
1 161 ASP n 
1 162 LYS n 
1 163 THR n 
1 164 LEU n 
1 165 PHE n 
1 166 LYS n 
1 167 TYR n 
1 168 PHE n 
1 169 MET n 
1 170 ARG n 
1 171 VAL n 
1 172 VAL n 
1 173 PRO n 
1 174 SER n 
1 175 ASP n 
1 176 ALA n 
1 177 GLN n 
1 178 GLN n 
1 179 ALA n 
1 180 ARG n 
1 181 ALA n 
1 182 MET n 
1 183 VAL n 
1 184 ASP n 
1 185 ILE n 
1 186 VAL n 
1 187 LYS n 
1 188 ARG n 
1 189 TYR n 
1 190 ASN n 
1 191 TRP n 
1 192 THR n 
1 193 TYR n 
1 194 VAL n 
1 195 SER n 
1 196 ALA n 
1 197 VAL n 
1 198 HIS n 
1 199 THR n 
1 200 GLU n 
1 201 GLY n 
1 202 ASN n 
1 203 TYR n 
1 204 GLY n 
1 205 GLU n 
1 206 SER n 
1 207 GLY n 
1 208 MET n 
1 209 GLU n 
1 210 ALA n 
1 211 PHE n 
1 212 LYS n 
1 213 ASP n 
1 214 MET n 
1 215 SER n 
1 216 ALA n 
1 217 LYS n 
1 218 GLU n 
1 219 GLY n 
1 220 ILE n 
1 221 CYS n 
1 222 ILE n 
1 223 ALA n 
1 224 HIS n 
1 225 SER n 
1 226 TYR n 
1 227 LYS n 
1 228 ILE n 
1 229 TYR n 
1 230 SER n 
1 231 ASN n 
1 232 ALA n 
1 233 GLY n 
1 234 GLU n 
1 235 GLN n 
1 236 SER n 
1 237 PHE n 
1 238 ASP n 
1 239 LYS n 
1 240 LEU n 
1 241 LEU n 
1 242 LYS n 
1 243 LYS n 
1 244 LEU n 
1 245 THR n 
1 246 SER n 
1 247 HIS n 
1 248 LEU n 
1 249 PRO n 
1 250 LYS n 
1 251 ALA n 
1 252 ARG n 
1 253 VAL n 
1 254 VAL n 
1 255 ALA n 
1 256 CYS n 
1 257 PHE n 
1 258 CYS n 
1 259 GLU n 
1 260 GLY n 
1 261 MET n 
1 262 THR n 
1 263 VAL n 
1 264 ARG n 
1 265 GLY n 
1 266 LEU n 
1 267 LEU n 
1 268 MET n 
1 269 ALA n 
1 270 MET n 
1 271 ARG n 
1 272 ARG n 
1 273 LEU n 
1 274 GLY n 
1 275 LEU n 
1 276 ALA n 
1 277 GLY n 
1 278 GLU n 
1 279 PHE n 
1 280 LEU n 
1 281 LEU n 
1 282 LEU n 
1 283 GLY n 
1 284 SER n 
1 285 ASP n 
1 286 GLY n 
1 287 TRP n 
1 288 ALA n 
1 289 ASP n 
1 290 ARG n 
1 291 TYR n 
1 292 ASP n 
1 293 VAL n 
1 294 THR n 
1 295 ASP n 
1 296 GLY n 
1 297 TYR n 
1 298 GLN n 
1 299 ARG n 
1 300 GLU n 
1 301 ALA n 
1 302 VAL n 
1 303 GLY n 
1 304 GLY n 
1 305 ILE n 
1 306 THR n 
1 307 ILE n 
1 308 LYS n 
1 309 LEU n 
1 310 GLN n 
1 311 SER n 
1 312 PRO n 
1 313 ASP n 
1 314 VAL n 
1 315 LYS n 
1 316 TRP n 
1 317 PHE n 
1 318 ASP n 
1 319 ASP n 
1 320 TYR n 
1 321 TYR n 
1 322 LEU n 
1 323 LYS n 
1 324 LEU n 
1 325 ARG n 
1 326 PRO n 
1 327 GLU n 
1 328 THR n 
1 329 ASN n 
1 330 LEU n 
1 331 ARG n 
1 332 ASN n 
1 333 PRO n 
1 334 TRP n 
1 335 PHE n 
1 336 GLN n 
1 337 GLU n 
1 338 PHE n 
1 339 TRP n 
1 340 GLN n 
1 341 HIS n 
1 342 ARG n 
1 343 PHE n 
1 344 GLN n 
1 345 CYS n 
1 346 ARG n 
1 347 LEU n 
1 348 GLU n 
1 349 GLY n 
1 350 PHE n 
1 351 PRO n 
1 352 GLN n 
1 353 GLU n 
1 354 ASN n 
1 355 SER n 
1 356 LYS n 
1 357 TYR n 
1 358 ASN n 
1 359 LYS n 
1 360 THR n 
1 361 CYS n 
1 362 ASN n 
1 363 SER n 
1 364 SER n 
1 365 LEU n 
1 366 THR n 
1 367 LEU n 
1 368 LYS n 
1 369 THR n 
1 370 HIS n 
1 371 HIS n 
1 372 VAL n 
1 373 GLN n 
1 374 ASP n 
1 375 SER n 
1 376 LYS n 
1 377 MET n 
1 378 GLY n 
1 379 PHE n 
1 380 VAL n 
1 381 ILE n 
1 382 ASN n 
1 383 ALA n 
1 384 ILE n 
1 385 TYR n 
1 386 SER n 
1 387 MET n 
1 388 ALA n 
1 389 TYR n 
1 390 GLY n 
1 391 LEU n 
1 392 HIS n 
1 393 ASN n 
1 394 MET n 
1 395 GLN n 
1 396 MET n 
1 397 SER n 
1 398 LEU n 
1 399 CYS n 
1 400 PRO n 
1 401 GLY n 
1 402 TYR n 
1 403 ALA n 
1 404 GLY n 
1 405 LEU n 
1 406 CYS n 
1 407 ASP n 
1 408 ALA n 
1 409 MET n 
1 410 LYS n 
1 411 PRO n 
1 412 ILE n 
1 413 ASP n 
1 414 GLY n 
1 415 ARG n 
1 416 LYS n 
1 417 LEU n 
1 418 LEU n 
1 419 GLU n 
1 420 SER n 
1 421 LEU n 
1 422 MET n 
1 423 LYS n 
1 424 THR n 
1 425 ALA n 
1 426 PHE n 
1 427 THR n 
1 428 GLY n 
1 429 VAL n 
1 430 SER n 
1 431 GLY n 
1 432 ASP n 
1 433 THR n 
1 434 ILE n 
1 435 LEU n 
1 436 PHE n 
1 437 ASP n 
1 438 GLU n 
1 439 ASN n 
1 440 GLY n 
1 441 ASP n 
1 442 SER n 
1 443 PRO n 
1 444 GLY n 
1 445 ARG n 
1 446 TYR n 
1 447 GLU n 
1 448 ILE n 
1 449 MET n 
1 450 ASN n 
1 451 PHE n 
1 452 LYS n 
1 453 GLU n 
1 454 MET n 
1 455 GLY n 
1 456 LYS n 
1 457 ASP n 
1 458 TYR n 
1 459 PHE n 
1 460 ASP n 
1 461 TYR n 
1 462 ILE n 
1 463 ASN n 
1 464 VAL n 
1 465 GLY n 
1 466 SER n 
1 467 TRP n 
1 468 ASP n 
1 469 ASN n 
1 470 GLY n 
1 471 GLU n 
1 472 LEU n 
1 473 LYS n 
1 474 MET n 
1 475 ASP n 
1 476 ASP n 
1 477 ASP n 
1 478 GLU n 
1 479 VAL n 
1 480 TRP n 
1 481 SER n 
1 482 LYS n 
1 483 LYS n 
1 484 SER n 
1 485 ASN n 
1 486 ILE n 
1 487 ILE n 
1 488 ARG n 
1 489 SER n 
1 490 VAL n 
1 491 CYS n 
1 492 SER n 
1 493 GLU n 
1 494 PRO n 
1 495 CYS n 
1 496 GLU n 
1 497 LYS n 
1 498 GLY n 
1 499 GLN n 
1 500 ILE n 
1 501 LYS n 
1 502 VAL n 
1 503 ILE n 
1 504 ARG n 
1 505 LYS n 
1 506 GLY n 
1 507 GLU n 
1 508 VAL n 
1 509 SER n 
1 510 CYS n 
1 511 CYS n 
1 512 TRP n 
1 513 THR n 
1 514 CYS n 
1 515 THR n 
1 516 PRO n 
1 517 CYS n 
1 518 LYS n 
1 519 GLU n 
1 520 ASN n 
1 521 GLU n 
1 522 TYR n 
1 523 VAL n 
1 524 PHE n 
1 525 ASP n 
1 526 GLU n 
1 527 TYR n 
1 528 THR n 
1 529 CYS n 
1 530 LYS n 
1 531 ALA n 
1 532 CYS n 
1 533 GLN n 
1 534 LEU n 
1 535 GLY n 
1 536 SER n 
1 537 TRP n 
1 538 PRO n 
1 539 THR n 
1 540 ASP n 
1 541 ASP n 
1 542 LEU n 
1 543 THR n 
1 544 GLY n 
1 545 CYS n 
1 546 ASP n 
1 547 LEU n 
1 548 ILE n 
1 549 PRO n 
1 550 VAL n 
1 551 GLN n 
1 552 TYR n 
1 553 LEU n 
1 554 ARG n 
1 555 TRP n 
1 556 GLY n 
1 557 ASP n 
1 558 PRO n 
1 559 GLU n 
1 560 PRO n 
1 561 ILE n 
1 562 ALA n 
1 563 ALA n 
1 564 VAL n 
1 565 VAL n 
1 566 PHE n 
1 567 ALA n 
1 568 CYS n 
1 569 LEU n 
1 570 GLY n 
1 571 LEU n 
1 572 LEU n 
1 573 ALA n 
1 574 THR n 
1 575 LEU n 
1 576 PHE n 
1 577 VAL n 
1 578 THR n 
1 579 VAL n 
1 580 VAL n 
1 581 PHE n 
1 582 ILE n 
1 583 ILE n 
1 584 TYR n 
1 585 ARG n 
1 586 ASP n 
1 587 THR n 
1 588 PRO n 
1 589 VAL n 
1 590 VAL n 
1 591 LYS n 
1 592 SER n 
1 593 SER n 
1 594 SER n 
1 595 ARG n 
1 596 GLU n 
1 597 LEU n 
1 598 CYS n 
1 599 TYR n 
1 600 ILE n 
1 601 ILE n 
1 602 LEU n 
1 603 ALA n 
1 604 GLY n 
1 605 ILE n 
1 606 CYS n 
1 607 LEU n 
1 608 GLY n 
1 609 TYR n 
1 610 LEU n 
1 611 CYS n 
1 612 THR n 
1 613 PHE n 
1 614 CYS n 
1 615 LEU n 
1 616 ILE n 
1 617 ALA n 
1 618 LYS n 
1 619 PRO n 
1 620 LYS n 
1 621 GLN n 
1 622 ILE n 
1 623 TYR n 
1 624 CYS n 
1 625 TYR n 
1 626 LEU n 
1 627 GLN n 
1 628 ARG n 
1 629 ILE n 
1 630 GLY n 
1 631 ILE n 
1 632 GLY n 
1 633 LEU n 
1 634 SER n 
1 635 PRO n 
1 636 ALA n 
1 637 MET n 
1 638 SER n 
1 639 TYR n 
1 640 SER n 
1 641 ALA n 
1 642 LEU n 
1 643 VAL n 
1 644 THR n 
1 645 LYS n 
1 646 THR n 
1 647 ASN n 
1 648 ARG n 
1 649 ILE n 
1 650 ALA n 
1 651 ARG n 
1 652 ILE n 
1 653 LEU n 
1 654 ALA n 
1 655 GLY n 
1 656 SER n 
1 657 LYS n 
1 658 LYS n 
1 659 LYS n 
1 660 ILE n 
1 661 CYS n 
1 662 THR n 
1 663 LYS n 
1 664 LYS n 
1 665 PRO n 
1 666 ARG n 
1 667 PHE n 
1 668 MET n 
1 669 SER n 
1 670 ALA n 
1 671 CYS n 
1 672 ALA n 
1 673 GLN n 
1 674 LEU n 
1 675 VAL n 
1 676 ILE n 
1 677 ALA n 
1 678 PHE n 
1 679 ILE n 
1 680 LEU n 
1 681 ILE n 
1 682 CYS n 
1 683 ILE n 
1 684 GLN n 
1 685 LEU n 
1 686 GLY n 
1 687 ILE n 
1 688 ILE n 
1 689 VAL n 
1 690 ALA n 
1 691 LEU n 
1 692 PHE n 
1 693 ILE n 
1 694 MET n 
1 695 GLU n 
1 696 PRO n 
1 697 PRO n 
1 698 ASP n 
1 699 ILE n 
1 700 MET n 
1 701 HIS n 
1 702 ASP n 
1 703 TYR n 
1 704 PRO n 
1 705 SER n 
1 706 ILE n 
1 707 ARG n 
1 708 GLU n 
1 709 VAL n 
1 710 TYR n 
1 711 LEU n 
1 712 ILE n 
1 713 CYS n 
1 714 ASN n 
1 715 THR n 
1 716 THR n 
1 717 ASN n 
1 718 LEU n 
1 719 GLY n 
1 720 VAL n 
1 721 VAL n 
1 722 ALA n 
1 723 PRO n 
1 724 LEU n 
1 725 GLY n 
1 726 TYR n 
1 727 ASN n 
1 728 GLY n 
1 729 LEU n 
1 730 LEU n 
1 731 ILE n 
1 732 LEU n 
1 733 ALA n 
1 734 CYS n 
1 735 THR n 
1 736 PHE n 
1 737 TYR n 
1 738 ALA n 
1 739 PHE n 
1 740 LYS n 
1 741 THR n 
1 742 ARG n 
1 743 ASN n 
1 744 VAL n 
1 745 PRO n 
1 746 ALA n 
1 747 ASN n 
1 748 PHE n 
1 749 ASN n 
1 750 GLU n 
1 751 ALA n 
1 752 LYS n 
1 753 TYR n 
1 754 ILE n 
1 755 ALA n 
1 756 PHE n 
1 757 ALA n 
1 758 MET n 
1 759 TYR n 
1 760 THR n 
1 761 THR n 
1 762 CYS n 
1 763 ILE n 
1 764 ILE n 
1 765 TRP n 
1 766 LEU n 
1 767 ALA n 
1 768 PHE n 
1 769 VAL n 
1 770 PRO n 
1 771 ILE n 
1 772 TYR n 
1 773 PHE n 
1 774 GLY n 
1 775 SER n 
1 776 ASN n 
1 777 TYR n 
1 778 LYS n 
1 779 ALA n 
1 780 ILE n 
1 781 THR n 
1 782 MET n 
1 783 CYS n 
1 784 PHE n 
1 785 SER n 
1 786 VAL n 
1 787 SER n 
1 788 LEU n 
1 789 SER n 
1 790 ALA n 
1 791 THR n 
1 792 VAL n 
1 793 LEU n 
1 794 LEU n 
1 795 GLY n 
1 796 CYS n 
1 797 MET n 
1 798 PHE n 
1 799 VAL n 
1 800 PRO n 
1 801 LYS n 
1 802 VAL n 
1 803 TYR n 
1 804 ILE n 
1 805 ILE n 
1 806 LEU n 
1 807 ALA n 
1 808 LYS n 
1 809 PRO n 
1 810 GLU n 
1 811 ARG n 
1 812 ASN n 
1 813 VAL n 
1 814 ARG n 
1 815 SER n 
1 816 ALA n 
1 817 PHE n 
1 818 THR n 
1 819 THR n 
1 820 SER n 
1 821 THR n 
1 822 VAL n 
1 823 VAL n 
1 824 ARG n 
1 825 MET n 
1 826 HIS n 
1 827 VAL n 
1 828 GLY n 
1 829 ASP n 
1 830 GLY n 
1 831 LYS n 
1 832 SER n 
1 833 SER n 
1 834 SER n 
1 835 ALA n 
1 836 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   836 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 GRM5 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            'HEK293S GnTI-' 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          plasmid 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       BacMam 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                                              ? 'C3 H7 N O2'      89.093 
ARG 'L-peptide linking'          y ARGININE                                                             ? 'C6 H15 N4 O2 1'  
175.209 
ASN 'L-peptide linking'          y ASPARAGINE                                                           ? 'C4 H8 N2 O3'     
132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                                                      ? 'C4 H7 N O4'      
133.103 
CYS 'L-peptide linking'          y CYSTEINE                                                             ? 'C3 H7 N O2 S'    
121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                                            ? 'C5 H10 N2 O3'    
146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                                                      ? 'C5 H9 N O4'      
147.129 
GLY 'peptide linking'            y GLYCINE                                                              ? 'C2 H5 N O2'      75.067 
HIS 'L-peptide linking'          y HISTIDINE                                                            ? 'C6 H10 N3 O2 1'  
156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                                                           ? 'C6 H13 N O2'     
131.173 
LEU 'L-peptide linking'          y LEUCINE                                                              ? 'C6 H13 N O2'     
131.173 
LYS 'L-peptide linking'          y LYSINE                                                               ? 'C6 H15 N2 O2 1'  
147.195 
MET 'L-peptide linking'          y METHIONINE                                                           ? 'C5 H11 N O2 S'   
149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose                             
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'     221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                                                        ? 'C9 H11 N O2'     
165.189 
PRO 'L-peptide linking'          y PROLINE                                                              ? 'C5 H9 N O2'      
115.130 
QUS non-polymer                  . '(S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID' QUISQUALATE 'C5 H7 N3 O5' 
189.126 
SER 'L-peptide linking'          y SERINE                                                               ? 'C3 H7 N O3'      
105.093 
THR 'L-peptide linking'          y THREONINE                                                            ? 'C4 H9 N O3'      
119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                                                           ? 'C11 H12 N2 O2'   
204.225 
TYR 'L-peptide linking'          y TYROSINE                                                             ? 'C9 H11 N O3'     
181.189 
VAL 'L-peptide linking'          y VALINE                                                               ? 'C5 H11 N O2'     
117.146 
XQT non-polymer                  . VU0424465                                                            
'5-[2-(3-fluorophenyl)ethynyl]-~{N}-[(2~{R})-3-methyl-3-oxidanyl-butan-2-yl]pyridine-2-carboxamide' 'C19 H19 F N2 O2' 326.365 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLN 1   21  ?   ?   ?   A . n 
A 1 2   SER 2   22  ?   ?   ?   A . n 
A 1 3   SER 3   23  ?   ?   ?   A . n 
A 1 4   GLU 4   24  ?   ?   ?   A . n 
A 1 5   ARG 5   25  25  ARG ARG A . n 
A 1 6   ARG 6   26  26  ARG ARG A . n 
A 1 7   VAL 7   27  27  VAL VAL A . n 
A 1 8   VAL 8   28  28  VAL VAL A . n 
A 1 9   ALA 9   29  29  ALA ALA A . n 
A 1 10  HIS 10  30  30  HIS HIS A . n 
A 1 11  MET 11  31  31  MET MET A . n 
A 1 12  PRO 12  32  32  PRO PRO A . n 
A 1 13  GLY 13  33  33  GLY GLY A . n 
A 1 14  ASP 14  34  34  ASP ASP A . n 
A 1 15  ILE 15  35  35  ILE ILE A . n 
A 1 16  ILE 16  36  36  ILE ILE A . n 
A 1 17  ILE 17  37  37  ILE ILE A . n 
A 1 18  GLY 18  38  38  GLY GLY A . n 
A 1 19  ALA 19  39  39  ALA ALA A . n 
A 1 20  LEU 20  40  40  LEU LEU A . n 
A 1 21  PHE 21  41  41  PHE PHE A . n 
A 1 22  SER 22  42  42  SER SER A . n 
A 1 23  VAL 23  43  43  VAL VAL A . n 
A 1 24  HIS 24  44  44  HIS HIS A . n 
A 1 25  HIS 25  45  45  HIS HIS A . n 
A 1 26  GLN 26  46  46  GLN GLN A . n 
A 1 27  PRO 27  47  47  PRO PRO A . n 
A 1 28  THR 28  48  48  THR THR A . n 
A 1 29  VAL 29  49  49  VAL VAL A . n 
A 1 30  ASP 30  50  50  ASP ASP A . n 
A 1 31  LYS 31  51  51  LYS LYS A . n 
A 1 32  VAL 32  52  52  VAL VAL A . n 
A 1 33  HIS 33  53  53  HIS HIS A . n 
A 1 34  GLU 34  54  54  GLU GLU A . n 
A 1 35  ARG 35  55  55  ARG ARG A . n 
A 1 36  LYS 36  56  56  LYS LYS A . n 
A 1 37  CYS 37  57  57  CYS CYS A . n 
A 1 38  GLY 38  58  58  GLY GLY A . n 
A 1 39  ALA 39  59  59  ALA ALA A . n 
A 1 40  VAL 40  60  60  VAL VAL A . n 
A 1 41  ARG 41  61  61  ARG ARG A . n 
A 1 42  GLU 42  62  62  GLU GLU A . n 
A 1 43  GLN 43  63  63  GLN GLN A . n 
A 1 44  TYR 44  64  64  TYR TYR A . n 
A 1 45  GLY 45  65  65  GLY GLY A . n 
A 1 46  ILE 46  66  66  ILE ILE A . n 
A 1 47  GLN 47  67  67  GLN GLN A . n 
A 1 48  ARG 48  68  68  ARG ARG A . n 
A 1 49  VAL 49  69  69  VAL VAL A . n 
A 1 50  GLU 50  70  70  GLU GLU A . n 
A 1 51  ALA 51  71  71  ALA ALA A . n 
A 1 52  MET 52  72  72  MET MET A . n 
A 1 53  LEU 53  73  73  LEU LEU A . n 
A 1 54  HIS 54  74  74  HIS HIS A . n 
A 1 55  THR 55  75  75  THR THR A . n 
A 1 56  LEU 56  76  76  LEU LEU A . n 
A 1 57  GLU 57  77  77  GLU GLU A . n 
A 1 58  ARG 58  78  78  ARG ARG A . n 
A 1 59  ILE 59  79  79  ILE ILE A . n 
A 1 60  ASN 60  80  80  ASN ASN A . n 
A 1 61  SER 61  81  81  SER SER A . n 
A 1 62  ASP 62  82  82  ASP ASP A . n 
A 1 63  PRO 63  83  83  PRO PRO A . n 
A 1 64  THR 64  84  84  THR THR A . n 
A 1 65  LEU 65  85  85  LEU LEU A . n 
A 1 66  LEU 66  86  86  LEU LEU A . n 
A 1 67  PRO 67  87  87  PRO PRO A . n 
A 1 68  ASN 68  88  88  ASN ASN A . n 
A 1 69  ILE 69  89  89  ILE ILE A . n 
A 1 70  THR 70  90  90  THR THR A . n 
A 1 71  LEU 71  91  91  LEU LEU A . n 
A 1 72  GLY 72  92  92  GLY GLY A . n 
A 1 73  CYS 73  93  93  CYS CYS A . n 
A 1 74  GLU 74  94  94  GLU GLU A . n 
A 1 75  ILE 75  95  95  ILE ILE A . n 
A 1 76  ARG 76  96  96  ARG ARG A . n 
A 1 77  ASP 77  97  97  ASP ASP A . n 
A 1 78  SER 78  98  98  SER SER A . n 
A 1 79  CYS 79  99  99  CYS CYS A . n 
A 1 80  TRP 80  100 100 TRP TRP A . n 
A 1 81  HIS 81  101 101 HIS HIS A . n 
A 1 82  SER 82  102 102 SER SER A . n 
A 1 83  ALA 83  103 103 ALA ALA A . n 
A 1 84  VAL 84  104 104 VAL VAL A . n 
A 1 85  ALA 85  105 105 ALA ALA A . n 
A 1 86  LEU 86  106 106 LEU LEU A . n 
A 1 87  GLU 87  107 107 GLU GLU A . n 
A 1 88  GLN 88  108 108 GLN GLN A . n 
A 1 89  SER 89  109 109 SER SER A . n 
A 1 90  ILE 90  110 110 ILE ILE A . n 
A 1 91  GLU 91  111 111 GLU GLU A . n 
A 1 92  PHE 92  112 112 PHE PHE A . n 
A 1 93  ILE 93  113 113 ILE ILE A . n 
A 1 94  ARG 94  114 114 ARG ARG A . n 
A 1 95  ASP 95  115 115 ASP ASP A . n 
A 1 96  SER 96  116 116 SER SER A . n 
A 1 97  LEU 97  117 117 LEU LEU A . n 
A 1 98  ILE 98  118 ?   ?   ?   A . n 
A 1 99  SER 99  119 ?   ?   ?   A . n 
A 1 100 SER 100 120 ?   ?   ?   A . n 
A 1 101 GLU 101 121 ?   ?   ?   A . n 
A 1 102 GLU 102 122 ?   ?   ?   A . n 
A 1 103 GLU 103 123 ?   ?   ?   A . n 
A 1 104 GLU 104 124 ?   ?   ?   A . n 
A 1 105 GLY 105 125 ?   ?   ?   A . n 
A 1 106 LEU 106 126 ?   ?   ?   A . n 
A 1 107 VAL 107 127 ?   ?   ?   A . n 
A 1 108 ARG 108 128 ?   ?   ?   A . n 
A 1 109 CYS 109 129 ?   ?   ?   A . n 
A 1 110 VAL 110 130 ?   ?   ?   A . n 
A 1 111 ASP 111 131 ?   ?   ?   A . n 
A 1 112 GLY 112 132 ?   ?   ?   A . n 
A 1 113 SER 113 133 ?   ?   ?   A . n 
A 1 114 SER 114 134 ?   ?   ?   A . n 
A 1 115 SER 115 135 ?   ?   ?   A . n 
A 1 116 SER 116 136 ?   ?   ?   A . n 
A 1 117 PHE 117 137 ?   ?   ?   A . n 
A 1 118 ARG 118 138 ?   ?   ?   A . n 
A 1 119 SER 119 139 ?   ?   ?   A . n 
A 1 120 LYS 120 140 ?   ?   ?   A . n 
A 1 121 LYS 121 141 141 LYS LYS A . n 
A 1 122 PRO 122 142 142 PRO PRO A . n 
A 1 123 ILE 123 143 143 ILE ILE A . n 
A 1 124 VAL 124 144 144 VAL VAL A . n 
A 1 125 GLY 125 145 145 GLY GLY A . n 
A 1 126 VAL 126 146 146 VAL VAL A . n 
A 1 127 ILE 127 147 147 ILE ILE A . n 
A 1 128 GLY 128 148 148 GLY GLY A . n 
A 1 129 PRO 129 149 149 PRO PRO A . n 
A 1 130 GLY 130 150 150 GLY GLY A . n 
A 1 131 SER 131 151 151 SER SER A . n 
A 1 132 SER 132 152 152 SER SER A . n 
A 1 133 SER 133 153 153 SER SER A . n 
A 1 134 VAL 134 154 154 VAL VAL A . n 
A 1 135 ALA 135 155 155 ALA ALA A . n 
A 1 136 ILE 136 156 156 ILE ILE A . n 
A 1 137 GLN 137 157 157 GLN GLN A . n 
A 1 138 VAL 138 158 158 VAL VAL A . n 
A 1 139 GLN 139 159 159 GLN GLN A . n 
A 1 140 ASN 140 160 160 ASN ASN A . n 
A 1 141 LEU 141 161 161 LEU LEU A . n 
A 1 142 LEU 142 162 162 LEU LEU A . n 
A 1 143 GLN 143 163 163 GLN GLN A . n 
A 1 144 LEU 144 164 164 LEU LEU A . n 
A 1 145 PHE 145 165 165 PHE PHE A . n 
A 1 146 ASN 146 166 166 ASN ASN A . n 
A 1 147 ILE 147 167 167 ILE ILE A . n 
A 1 148 PRO 148 168 168 PRO PRO A . n 
A 1 149 GLN 149 169 169 GLN GLN A . n 
A 1 150 ILE 150 170 170 ILE ILE A . n 
A 1 151 ALA 151 171 171 ALA ALA A . n 
A 1 152 TYR 152 172 172 TYR TYR A . n 
A 1 153 SER 153 173 173 SER SER A . n 
A 1 154 ALA 154 174 174 ALA ALA A . n 
A 1 155 THR 155 175 175 THR THR A . n 
A 1 156 SER 156 176 176 SER SER A . n 
A 1 157 MET 157 177 177 MET MET A . n 
A 1 158 ASP 158 178 178 ASP ASP A . n 
A 1 159 LEU 159 179 179 LEU LEU A . n 
A 1 160 SER 160 180 180 SER SER A . n 
A 1 161 ASP 161 181 181 ASP ASP A . n 
A 1 162 LYS 162 182 182 LYS LYS A . n 
A 1 163 THR 163 183 183 THR THR A . n 
A 1 164 LEU 164 184 184 LEU LEU A . n 
A 1 165 PHE 165 185 185 PHE PHE A . n 
A 1 166 LYS 166 186 186 LYS LYS A . n 
A 1 167 TYR 167 187 187 TYR TYR A . n 
A 1 168 PHE 168 188 188 PHE PHE A . n 
A 1 169 MET 169 189 189 MET MET A . n 
A 1 170 ARG 170 190 190 ARG ARG A . n 
A 1 171 VAL 171 191 191 VAL VAL A . n 
A 1 172 VAL 172 192 192 VAL VAL A . n 
A 1 173 PRO 173 193 193 PRO PRO A . n 
A 1 174 SER 174 194 194 SER SER A . n 
A 1 175 ASP 175 195 195 ASP ASP A . n 
A 1 176 ALA 176 196 196 ALA ALA A . n 
A 1 177 GLN 177 197 197 GLN GLN A . n 
A 1 178 GLN 178 198 198 GLN GLN A . n 
A 1 179 ALA 179 199 199 ALA ALA A . n 
A 1 180 ARG 180 200 200 ARG ARG A . n 
A 1 181 ALA 181 201 201 ALA ALA A . n 
A 1 182 MET 182 202 202 MET MET A . n 
A 1 183 VAL 183 203 203 VAL VAL A . n 
A 1 184 ASP 184 204 204 ASP ASP A . n 
A 1 185 ILE 185 205 205 ILE ILE A . n 
A 1 186 VAL 186 206 206 VAL VAL A . n 
A 1 187 LYS 187 207 207 LYS LYS A . n 
A 1 188 ARG 188 208 208 ARG ARG A . n 
A 1 189 TYR 189 209 209 TYR TYR A . n 
A 1 190 ASN 190 210 210 ASN ASN A . n 
A 1 191 TRP 191 211 211 TRP TRP A . n 
A 1 192 THR 192 212 212 THR THR A . n 
A 1 193 TYR 193 213 213 TYR TYR A . n 
A 1 194 VAL 194 214 214 VAL VAL A . n 
A 1 195 SER 195 215 215 SER SER A . n 
A 1 196 ALA 196 216 216 ALA ALA A . n 
A 1 197 VAL 197 217 217 VAL VAL A . n 
A 1 198 HIS 198 218 218 HIS HIS A . n 
A 1 199 THR 199 219 219 THR THR A . n 
A 1 200 GLU 200 220 220 GLU GLU A . n 
A 1 201 GLY 201 221 221 GLY GLY A . n 
A 1 202 ASN 202 222 222 ASN ASN A . n 
A 1 203 TYR 203 223 223 TYR TYR A . n 
A 1 204 GLY 204 224 224 GLY GLY A . n 
A 1 205 GLU 205 225 225 GLU GLU A . n 
A 1 206 SER 206 226 226 SER SER A . n 
A 1 207 GLY 207 227 227 GLY GLY A . n 
A 1 208 MET 208 228 228 MET MET A . n 
A 1 209 GLU 209 229 229 GLU GLU A . n 
A 1 210 ALA 210 230 230 ALA ALA A . n 
A 1 211 PHE 211 231 231 PHE PHE A . n 
A 1 212 LYS 212 232 232 LYS LYS A . n 
A 1 213 ASP 213 233 233 ASP ASP A . n 
A 1 214 MET 214 234 234 MET MET A . n 
A 1 215 SER 215 235 235 SER SER A . n 
A 1 216 ALA 216 236 236 ALA ALA A . n 
A 1 217 LYS 217 237 237 LYS LYS A . n 
A 1 218 GLU 218 238 238 GLU GLU A . n 
A 1 219 GLY 219 239 239 GLY GLY A . n 
A 1 220 ILE 220 240 240 ILE ILE A . n 
A 1 221 CYS 221 241 241 CYS CYS A . n 
A 1 222 ILE 222 242 242 ILE ILE A . n 
A 1 223 ALA 223 243 243 ALA ALA A . n 
A 1 224 HIS 224 244 244 HIS HIS A . n 
A 1 225 SER 225 245 245 SER SER A . n 
A 1 226 TYR 226 246 246 TYR TYR A . n 
A 1 227 LYS 227 247 247 LYS LYS A . n 
A 1 228 ILE 228 248 248 ILE ILE A . n 
A 1 229 TYR 229 249 249 TYR TYR A . n 
A 1 230 SER 230 250 250 SER SER A . n 
A 1 231 ASN 231 251 251 ASN ASN A . n 
A 1 232 ALA 232 252 252 ALA ALA A . n 
A 1 233 GLY 233 253 253 GLY GLY A . n 
A 1 234 GLU 234 254 254 GLU GLU A . n 
A 1 235 GLN 235 255 255 GLN GLN A . n 
A 1 236 SER 236 256 256 SER SER A . n 
A 1 237 PHE 237 257 257 PHE PHE A . n 
A 1 238 ASP 238 258 258 ASP ASP A . n 
A 1 239 LYS 239 259 259 LYS LYS A . n 
A 1 240 LEU 240 260 260 LEU LEU A . n 
A 1 241 LEU 241 261 261 LEU LEU A . n 
A 1 242 LYS 242 262 262 LYS LYS A . n 
A 1 243 LYS 243 263 263 LYS LYS A . n 
A 1 244 LEU 244 264 264 LEU LEU A . n 
A 1 245 THR 245 265 265 THR THR A . n 
A 1 246 SER 246 266 266 SER SER A . n 
A 1 247 HIS 247 267 267 HIS HIS A . n 
A 1 248 LEU 248 268 268 LEU LEU A . n 
A 1 249 PRO 249 269 269 PRO PRO A . n 
A 1 250 LYS 250 270 270 LYS LYS A . n 
A 1 251 ALA 251 271 271 ALA ALA A . n 
A 1 252 ARG 252 272 272 ARG ARG A . n 
A 1 253 VAL 253 273 273 VAL VAL A . n 
A 1 254 VAL 254 274 274 VAL VAL A . n 
A 1 255 ALA 255 275 275 ALA ALA A . n 
A 1 256 CYS 256 276 276 CYS CYS A . n 
A 1 257 PHE 257 277 277 PHE PHE A . n 
A 1 258 CYS 258 278 278 CYS CYS A . n 
A 1 259 GLU 259 279 279 GLU GLU A . n 
A 1 260 GLY 260 280 280 GLY GLY A . n 
A 1 261 MET 261 281 281 MET MET A . n 
A 1 262 THR 262 282 282 THR THR A . n 
A 1 263 VAL 263 283 283 VAL VAL A . n 
A 1 264 ARG 264 284 284 ARG ARG A . n 
A 1 265 GLY 265 285 285 GLY GLY A . n 
A 1 266 LEU 266 286 286 LEU LEU A . n 
A 1 267 LEU 267 287 287 LEU LEU A . n 
A 1 268 MET 268 288 288 MET MET A . n 
A 1 269 ALA 269 289 289 ALA ALA A . n 
A 1 270 MET 270 290 290 MET MET A . n 
A 1 271 ARG 271 291 291 ARG ARG A . n 
A 1 272 ARG 272 292 292 ARG ARG A . n 
A 1 273 LEU 273 293 293 LEU LEU A . n 
A 1 274 GLY 274 294 294 GLY GLY A . n 
A 1 275 LEU 275 295 295 LEU LEU A . n 
A 1 276 ALA 276 296 296 ALA ALA A . n 
A 1 277 GLY 277 297 297 GLY GLY A . n 
A 1 278 GLU 278 298 298 GLU GLU A . n 
A 1 279 PHE 279 299 299 PHE PHE A . n 
A 1 280 LEU 280 300 300 LEU LEU A . n 
A 1 281 LEU 281 301 301 LEU LEU A . n 
A 1 282 LEU 282 302 302 LEU LEU A . n 
A 1 283 GLY 283 303 303 GLY GLY A . n 
A 1 284 SER 284 304 304 SER SER A . n 
A 1 285 ASP 285 305 305 ASP ASP A . n 
A 1 286 GLY 286 306 306 GLY GLY A . n 
A 1 287 TRP 287 307 307 TRP TRP A . n 
A 1 288 ALA 288 308 308 ALA ALA A . n 
A 1 289 ASP 289 309 309 ASP ASP A . n 
A 1 290 ARG 290 310 310 ARG ARG A . n 
A 1 291 TYR 291 311 311 TYR TYR A . n 
A 1 292 ASP 292 312 312 ASP ASP A . n 
A 1 293 VAL 293 313 313 VAL VAL A . n 
A 1 294 THR 294 314 314 THR THR A . n 
A 1 295 ASP 295 315 315 ASP ASP A . n 
A 1 296 GLY 296 316 316 GLY GLY A . n 
A 1 297 TYR 297 317 317 TYR TYR A . n 
A 1 298 GLN 298 318 318 GLN GLN A . n 
A 1 299 ARG 299 319 319 ARG ARG A . n 
A 1 300 GLU 300 320 320 GLU GLU A . n 
A 1 301 ALA 301 321 321 ALA ALA A . n 
A 1 302 VAL 302 322 322 VAL VAL A . n 
A 1 303 GLY 303 323 323 GLY GLY A . n 
A 1 304 GLY 304 324 324 GLY GLY A . n 
A 1 305 ILE 305 325 325 ILE ILE A . n 
A 1 306 THR 306 326 326 THR THR A . n 
A 1 307 ILE 307 327 327 ILE ILE A . n 
A 1 308 LYS 308 328 328 LYS LYS A . n 
A 1 309 LEU 309 329 329 LEU LEU A . n 
A 1 310 GLN 310 330 330 GLN GLN A . n 
A 1 311 SER 311 331 331 SER SER A . n 
A 1 312 PRO 312 332 332 PRO PRO A . n 
A 1 313 ASP 313 333 333 ASP ASP A . n 
A 1 314 VAL 314 334 334 VAL VAL A . n 
A 1 315 LYS 315 335 335 LYS LYS A . n 
A 1 316 TRP 316 336 336 TRP TRP A . n 
A 1 317 PHE 317 337 337 PHE PHE A . n 
A 1 318 ASP 318 338 338 ASP ASP A . n 
A 1 319 ASP 319 339 339 ASP ASP A . n 
A 1 320 TYR 320 340 340 TYR TYR A . n 
A 1 321 TYR 321 341 341 TYR TYR A . n 
A 1 322 LEU 322 342 342 LEU LEU A . n 
A 1 323 LYS 323 343 343 LYS LYS A . n 
A 1 324 LEU 324 344 344 LEU LEU A . n 
A 1 325 ARG 325 345 345 ARG ARG A . n 
A 1 326 PRO 326 346 346 PRO PRO A . n 
A 1 327 GLU 327 347 347 GLU GLU A . n 
A 1 328 THR 328 348 348 THR THR A . n 
A 1 329 ASN 329 349 349 ASN ASN A . n 
A 1 330 LEU 330 350 350 LEU LEU A . n 
A 1 331 ARG 331 351 351 ARG ARG A . n 
A 1 332 ASN 332 352 352 ASN ASN A . n 
A 1 333 PRO 333 353 353 PRO PRO A . n 
A 1 334 TRP 334 354 354 TRP TRP A . n 
A 1 335 PHE 335 355 355 PHE PHE A . n 
A 1 336 GLN 336 356 356 GLN GLN A . n 
A 1 337 GLU 337 357 357 GLU GLU A . n 
A 1 338 PHE 338 358 358 PHE PHE A . n 
A 1 339 TRP 339 359 359 TRP TRP A . n 
A 1 340 GLN 340 360 360 GLN GLN A . n 
A 1 341 HIS 341 361 361 HIS HIS A . n 
A 1 342 ARG 342 362 362 ARG ARG A . n 
A 1 343 PHE 343 363 363 PHE PHE A . n 
A 1 344 GLN 344 364 364 GLN GLN A . n 
A 1 345 CYS 345 365 365 CYS CYS A . n 
A 1 346 ARG 346 366 366 ARG ARG A . n 
A 1 347 LEU 347 367 367 LEU LEU A . n 
A 1 348 GLU 348 368 368 GLU GLU A . n 
A 1 349 GLY 349 369 369 GLY GLY A . n 
A 1 350 PHE 350 370 370 PHE PHE A . n 
A 1 351 PRO 351 371 371 PRO PRO A . n 
A 1 352 GLN 352 372 372 GLN GLN A . n 
A 1 353 GLU 353 373 373 GLU GLU A . n 
A 1 354 ASN 354 374 374 ASN ASN A . n 
A 1 355 SER 355 375 375 SER SER A . n 
A 1 356 LYS 356 376 376 LYS LYS A . n 
A 1 357 TYR 357 377 377 TYR TYR A . n 
A 1 358 ASN 358 378 378 ASN ASN A . n 
A 1 359 LYS 359 379 379 LYS LYS A . n 
A 1 360 THR 360 380 380 THR THR A . n 
A 1 361 CYS 361 381 381 CYS CYS A . n 
A 1 362 ASN 362 382 382 ASN ASN A . n 
A 1 363 SER 363 383 383 SER SER A . n 
A 1 364 SER 364 384 384 SER SER A . n 
A 1 365 LEU 365 385 385 LEU LEU A . n 
A 1 366 THR 366 386 386 THR THR A . n 
A 1 367 LEU 367 387 387 LEU LEU A . n 
A 1 368 LYS 368 388 388 LYS LYS A . n 
A 1 369 THR 369 389 389 THR THR A . n 
A 1 370 HIS 370 390 390 HIS HIS A . n 
A 1 371 HIS 371 391 391 HIS HIS A . n 
A 1 372 VAL 372 392 392 VAL VAL A . n 
A 1 373 GLN 373 393 393 GLN GLN A . n 
A 1 374 ASP 374 394 394 ASP ASP A . n 
A 1 375 SER 375 395 395 SER SER A . n 
A 1 376 LYS 376 396 396 LYS LYS A . n 
A 1 377 MET 377 397 397 MET MET A . n 
A 1 378 GLY 378 398 398 GLY GLY A . n 
A 1 379 PHE 379 399 399 PHE PHE A . n 
A 1 380 VAL 380 400 400 VAL VAL A . n 
A 1 381 ILE 381 401 401 ILE ILE A . n 
A 1 382 ASN 382 402 402 ASN ASN A . n 
A 1 383 ALA 383 403 403 ALA ALA A . n 
A 1 384 ILE 384 404 404 ILE ILE A . n 
A 1 385 TYR 385 405 405 TYR TYR A . n 
A 1 386 SER 386 406 406 SER SER A . n 
A 1 387 MET 387 407 407 MET MET A . n 
A 1 388 ALA 388 408 408 ALA ALA A . n 
A 1 389 TYR 389 409 409 TYR TYR A . n 
A 1 390 GLY 390 410 410 GLY GLY A . n 
A 1 391 LEU 391 411 411 LEU LEU A . n 
A 1 392 HIS 392 412 412 HIS HIS A . n 
A 1 393 ASN 393 413 413 ASN ASN A . n 
A 1 394 MET 394 414 414 MET MET A . n 
A 1 395 GLN 395 415 415 GLN GLN A . n 
A 1 396 MET 396 416 416 MET MET A . n 
A 1 397 SER 397 417 417 SER SER A . n 
A 1 398 LEU 398 418 418 LEU LEU A . n 
A 1 399 CYS 399 419 419 CYS CYS A . n 
A 1 400 PRO 400 420 420 PRO PRO A . n 
A 1 401 GLY 401 421 421 GLY GLY A . n 
A 1 402 TYR 402 422 422 TYR TYR A . n 
A 1 403 ALA 403 423 423 ALA ALA A . n 
A 1 404 GLY 404 424 424 GLY GLY A . n 
A 1 405 LEU 405 425 425 LEU LEU A . n 
A 1 406 CYS 406 426 426 CYS CYS A . n 
A 1 407 ASP 407 427 427 ASP ASP A . n 
A 1 408 ALA 408 428 428 ALA ALA A . n 
A 1 409 MET 409 429 429 MET MET A . n 
A 1 410 LYS 410 430 430 LYS LYS A . n 
A 1 411 PRO 411 431 431 PRO PRO A . n 
A 1 412 ILE 412 432 432 ILE ILE A . n 
A 1 413 ASP 413 433 433 ASP ASP A . n 
A 1 414 GLY 414 434 434 GLY GLY A . n 
A 1 415 ARG 415 435 435 ARG ARG A . n 
A 1 416 LYS 416 436 436 LYS LYS A . n 
A 1 417 LEU 417 437 437 LEU LEU A . n 
A 1 418 LEU 418 438 438 LEU LEU A . n 
A 1 419 GLU 419 439 439 GLU GLU A . n 
A 1 420 SER 420 440 440 SER SER A . n 
A 1 421 LEU 421 441 441 LEU LEU A . n 
A 1 422 MET 422 442 442 MET MET A . n 
A 1 423 LYS 423 443 443 LYS LYS A . n 
A 1 424 THR 424 444 444 THR THR A . n 
A 1 425 ALA 425 445 445 ALA ALA A . n 
A 1 426 PHE 426 446 446 PHE PHE A . n 
A 1 427 THR 427 447 447 THR THR A . n 
A 1 428 GLY 428 448 448 GLY GLY A . n 
A 1 429 VAL 429 449 449 VAL VAL A . n 
A 1 430 SER 430 450 450 SER SER A . n 
A 1 431 GLY 431 451 451 GLY GLY A . n 
A 1 432 ASP 432 452 452 ASP ASP A . n 
A 1 433 THR 433 453 453 THR THR A . n 
A 1 434 ILE 434 454 454 ILE ILE A . n 
A 1 435 LEU 435 455 455 LEU LEU A . n 
A 1 436 PHE 436 456 456 PHE PHE A . n 
A 1 437 ASP 437 457 457 ASP ASP A . n 
A 1 438 GLU 438 458 458 GLU GLU A . n 
A 1 439 ASN 439 459 459 ASN ASN A . n 
A 1 440 GLY 440 460 460 GLY GLY A . n 
A 1 441 ASP 441 461 461 ASP ASP A . n 
A 1 442 SER 442 462 462 SER SER A . n 
A 1 443 PRO 443 463 463 PRO PRO A . n 
A 1 444 GLY 444 464 464 GLY GLY A . n 
A 1 445 ARG 445 465 465 ARG ARG A . n 
A 1 446 TYR 446 466 466 TYR TYR A . n 
A 1 447 GLU 447 467 467 GLU GLU A . n 
A 1 448 ILE 448 468 468 ILE ILE A . n 
A 1 449 MET 449 469 469 MET MET A . n 
A 1 450 ASN 450 470 470 ASN ASN A . n 
A 1 451 PHE 451 471 471 PHE PHE A . n 
A 1 452 LYS 452 472 472 LYS LYS A . n 
A 1 453 GLU 453 473 473 GLU GLU A . n 
A 1 454 MET 454 474 474 MET MET A . n 
A 1 455 GLY 455 475 475 GLY GLY A . n 
A 1 456 LYS 456 476 476 LYS LYS A . n 
A 1 457 ASP 457 477 477 ASP ASP A . n 
A 1 458 TYR 458 478 478 TYR TYR A . n 
A 1 459 PHE 459 479 479 PHE PHE A . n 
A 1 460 ASP 460 480 480 ASP ASP A . n 
A 1 461 TYR 461 481 481 TYR TYR A . n 
A 1 462 ILE 462 482 482 ILE ILE A . n 
A 1 463 ASN 463 483 483 ASN ASN A . n 
A 1 464 VAL 464 484 484 VAL VAL A . n 
A 1 465 GLY 465 485 485 GLY GLY A . n 
A 1 466 SER 466 486 486 SER SER A . n 
A 1 467 TRP 467 487 487 TRP TRP A . n 
A 1 468 ASP 468 488 488 ASP ASP A . n 
A 1 469 ASN 469 489 489 ASN ASN A . n 
A 1 470 GLY 470 490 490 GLY GLY A . n 
A 1 471 GLU 471 491 491 GLU GLU A . n 
A 1 472 LEU 472 492 492 LEU LEU A . n 
A 1 473 LYS 473 493 493 LYS LYS A . n 
A 1 474 MET 474 494 494 MET MET A . n 
A 1 475 ASP 475 495 495 ASP ASP A . n 
A 1 476 ASP 476 496 496 ASP ASP A . n 
A 1 477 ASP 477 497 497 ASP ASP A . n 
A 1 478 GLU 478 498 498 GLU GLU A . n 
A 1 479 VAL 479 499 499 VAL VAL A . n 
A 1 480 TRP 480 500 500 TRP TRP A . n 
A 1 481 SER 481 501 501 SER SER A . n 
A 1 482 LYS 482 502 502 LYS LYS A . n 
A 1 483 LYS 483 503 503 LYS LYS A . n 
A 1 484 SER 484 504 504 SER SER A . n 
A 1 485 ASN 485 505 505 ASN ASN A . n 
A 1 486 ILE 486 506 506 ILE ILE A . n 
A 1 487 ILE 487 507 507 ILE ILE A . n 
A 1 488 ARG 488 508 508 ARG ARG A . n 
A 1 489 SER 489 509 509 SER SER A . n 
A 1 490 VAL 490 510 510 VAL VAL A . n 
A 1 491 CYS 491 511 511 CYS CYS A . n 
A 1 492 SER 492 512 512 SER SER A . n 
A 1 493 GLU 493 513 513 GLU GLU A . n 
A 1 494 PRO 494 514 514 PRO PRO A . n 
A 1 495 CYS 495 515 515 CYS CYS A . n 
A 1 496 GLU 496 516 516 GLU GLU A . n 
A 1 497 LYS 497 517 517 LYS LYS A . n 
A 1 498 GLY 498 518 518 GLY GLY A . n 
A 1 499 GLN 499 519 519 GLN GLN A . n 
A 1 500 ILE 500 520 520 ILE ILE A . n 
A 1 501 LYS 501 521 521 LYS LYS A . n 
A 1 502 VAL 502 522 522 VAL VAL A . n 
A 1 503 ILE 503 523 523 ILE ILE A . n 
A 1 504 ARG 504 524 524 ARG ARG A . n 
A 1 505 LYS 505 525 525 LYS LYS A . n 
A 1 506 GLY 506 526 526 GLY GLY A . n 
A 1 507 GLU 507 527 527 GLU GLU A . n 
A 1 508 VAL 508 528 528 VAL VAL A . n 
A 1 509 SER 509 529 529 SER SER A . n 
A 1 510 CYS 510 530 530 CYS CYS A . n 
A 1 511 CYS 511 531 531 CYS CYS A . n 
A 1 512 TRP 512 532 532 TRP TRP A . n 
A 1 513 THR 513 533 533 THR THR A . n 
A 1 514 CYS 514 534 534 CYS CYS A . n 
A 1 515 THR 515 535 535 THR THR A . n 
A 1 516 PRO 516 536 536 PRO PRO A . n 
A 1 517 CYS 517 537 537 CYS CYS A . n 
A 1 518 LYS 518 538 538 LYS LYS A . n 
A 1 519 GLU 519 539 539 GLU GLU A . n 
A 1 520 ASN 520 540 540 ASN ASN A . n 
A 1 521 GLU 521 541 541 GLU GLU A . n 
A 1 522 TYR 522 542 542 TYR TYR A . n 
A 1 523 VAL 523 543 543 VAL VAL A . n 
A 1 524 PHE 524 544 544 PHE PHE A . n 
A 1 525 ASP 525 545 545 ASP ASP A . n 
A 1 526 GLU 526 546 546 GLU GLU A . n 
A 1 527 TYR 527 547 547 TYR TYR A . n 
A 1 528 THR 528 548 548 THR THR A . n 
A 1 529 CYS 529 549 549 CYS CYS A . n 
A 1 530 LYS 530 550 550 LYS LYS A . n 
A 1 531 ALA 531 551 551 ALA ALA A . n 
A 1 532 CYS 532 552 552 CYS CYS A . n 
A 1 533 GLN 533 553 553 GLN GLN A . n 
A 1 534 LEU 534 554 554 LEU LEU A . n 
A 1 535 GLY 535 555 555 GLY GLY A . n 
A 1 536 SER 536 556 556 SER SER A . n 
A 1 537 TRP 537 557 557 TRP TRP A . n 
A 1 538 PRO 538 558 558 PRO PRO A . n 
A 1 539 THR 539 559 559 THR THR A . n 
A 1 540 ASP 540 560 560 ASP ASP A . n 
A 1 541 ASP 541 561 561 ASP ASP A . n 
A 1 542 LEU 542 562 562 LEU LEU A . n 
A 1 543 THR 543 563 563 THR THR A . n 
A 1 544 GLY 544 564 564 GLY GLY A . n 
A 1 545 CYS 545 565 565 CYS CYS A . n 
A 1 546 ASP 546 566 566 ASP ASP A . n 
A 1 547 LEU 547 567 567 LEU LEU A . n 
A 1 548 ILE 548 568 568 ILE ILE A . n 
A 1 549 PRO 549 569 569 PRO PRO A . n 
A 1 550 VAL 550 570 570 VAL VAL A . n 
A 1 551 GLN 551 571 571 GLN GLN A . n 
A 1 552 TYR 552 572 572 TYR TYR A . n 
A 1 553 LEU 553 573 573 LEU LEU A . n 
A 1 554 ARG 554 574 574 ARG ARG A . n 
A 1 555 TRP 555 575 575 TRP TRP A . n 
A 1 556 GLY 556 576 576 GLY GLY A . n 
A 1 557 ASP 557 577 577 ASP ASP A . n 
A 1 558 PRO 558 578 578 PRO PRO A . n 
A 1 559 GLU 559 579 579 GLU GLU A . n 
A 1 560 PRO 560 580 580 PRO PRO A . n 
A 1 561 ILE 561 581 581 ILE ILE A . n 
A 1 562 ALA 562 582 582 ALA ALA A . n 
A 1 563 ALA 563 583 583 ALA ALA A . n 
A 1 564 VAL 564 584 584 VAL VAL A . n 
A 1 565 VAL 565 585 585 VAL VAL A . n 
A 1 566 PHE 566 586 586 PHE PHE A . n 
A 1 567 ALA 567 587 587 ALA ALA A . n 
A 1 568 CYS 568 588 588 CYS CYS A . n 
A 1 569 LEU 569 589 589 LEU LEU A . n 
A 1 570 GLY 570 590 590 GLY GLY A . n 
A 1 571 LEU 571 591 591 LEU LEU A . n 
A 1 572 LEU 572 592 592 LEU LEU A . n 
A 1 573 ALA 573 593 593 ALA ALA A . n 
A 1 574 THR 574 594 594 THR THR A . n 
A 1 575 LEU 575 595 595 LEU LEU A . n 
A 1 576 PHE 576 596 596 PHE PHE A . n 
A 1 577 VAL 577 597 597 VAL VAL A . n 
A 1 578 THR 578 598 598 THR THR A . n 
A 1 579 VAL 579 599 599 VAL VAL A . n 
A 1 580 VAL 580 600 600 VAL VAL A . n 
A 1 581 PHE 581 601 601 PHE PHE A . n 
A 1 582 ILE 582 602 602 ILE ILE A . n 
A 1 583 ILE 583 603 603 ILE ILE A . n 
A 1 584 TYR 584 604 604 TYR TYR A . n 
A 1 585 ARG 585 605 605 ARG ARG A . n 
A 1 586 ASP 586 606 606 ASP ASP A . n 
A 1 587 THR 587 607 607 THR THR A . n 
A 1 588 PRO 588 608 608 PRO PRO A . n 
A 1 589 VAL 589 609 609 VAL VAL A . n 
A 1 590 VAL 590 610 610 VAL VAL A . n 
A 1 591 LYS 591 611 611 LYS LYS A . n 
A 1 592 SER 592 612 612 SER SER A . n 
A 1 593 SER 593 613 613 SER SER A . n 
A 1 594 SER 594 614 614 SER SER A . n 
A 1 595 ARG 595 615 615 ARG ARG A . n 
A 1 596 GLU 596 616 616 GLU GLU A . n 
A 1 597 LEU 597 617 617 LEU LEU A . n 
A 1 598 CYS 598 618 618 CYS CYS A . n 
A 1 599 TYR 599 619 619 TYR TYR A . n 
A 1 600 ILE 600 620 620 ILE ILE A . n 
A 1 601 ILE 601 621 621 ILE ILE A . n 
A 1 602 LEU 602 622 622 LEU LEU A . n 
A 1 603 ALA 603 623 623 ALA ALA A . n 
A 1 604 GLY 604 624 624 GLY GLY A . n 
A 1 605 ILE 605 625 625 ILE ILE A . n 
A 1 606 CYS 606 626 626 CYS CYS A . n 
A 1 607 LEU 607 627 627 LEU LEU A . n 
A 1 608 GLY 608 628 628 GLY GLY A . n 
A 1 609 TYR 609 629 629 TYR TYR A . n 
A 1 610 LEU 610 630 630 LEU LEU A . n 
A 1 611 CYS 611 631 631 CYS CYS A . n 
A 1 612 THR 612 632 632 THR THR A . n 
A 1 613 PHE 613 633 633 PHE PHE A . n 
A 1 614 CYS 614 634 634 CYS CYS A . n 
A 1 615 LEU 615 635 635 LEU LEU A . n 
A 1 616 ILE 616 636 636 ILE ILE A . n 
A 1 617 ALA 617 637 637 ALA ALA A . n 
A 1 618 LYS 618 638 638 LYS LYS A . n 
A 1 619 PRO 619 639 639 PRO PRO A . n 
A 1 620 LYS 620 640 640 LYS LYS A . n 
A 1 621 GLN 621 641 641 GLN GLN A . n 
A 1 622 ILE 622 642 642 ILE ILE A . n 
A 1 623 TYR 623 643 643 TYR TYR A . n 
A 1 624 CYS 624 644 644 CYS CYS A . n 
A 1 625 TYR 625 645 645 TYR TYR A . n 
A 1 626 LEU 626 646 646 LEU LEU A . n 
A 1 627 GLN 627 647 647 GLN GLN A . n 
A 1 628 ARG 628 648 648 ARG ARG A . n 
A 1 629 ILE 629 649 649 ILE ILE A . n 
A 1 630 GLY 630 650 650 GLY GLY A . n 
A 1 631 ILE 631 651 651 ILE ILE A . n 
A 1 632 GLY 632 652 652 GLY GLY A . n 
A 1 633 LEU 633 653 653 LEU LEU A . n 
A 1 634 SER 634 654 654 SER SER A . n 
A 1 635 PRO 635 655 655 PRO PRO A . n 
A 1 636 ALA 636 656 656 ALA ALA A . n 
A 1 637 MET 637 657 657 MET MET A . n 
A 1 638 SER 638 658 658 SER SER A . n 
A 1 639 TYR 639 659 659 TYR TYR A . n 
A 1 640 SER 640 660 660 SER SER A . n 
A 1 641 ALA 641 661 661 ALA ALA A . n 
A 1 642 LEU 642 662 662 LEU LEU A . n 
A 1 643 VAL 643 663 663 VAL VAL A . n 
A 1 644 THR 644 664 664 THR THR A . n 
A 1 645 LYS 645 665 665 LYS LYS A . n 
A 1 646 THR 646 666 666 THR THR A . n 
A 1 647 ASN 647 667 667 ASN ASN A . n 
A 1 648 ARG 648 668 668 ARG ARG A . n 
A 1 649 ILE 649 669 669 ILE ILE A . n 
A 1 650 ALA 650 670 670 ALA ALA A . n 
A 1 651 ARG 651 671 671 ARG ARG A . n 
A 1 652 ILE 652 672 672 ILE ILE A . n 
A 1 653 LEU 653 673 673 LEU LEU A . n 
A 1 654 ALA 654 674 674 ALA ALA A . n 
A 1 655 GLY 655 675 675 GLY GLY A . n 
A 1 656 SER 656 676 ?   ?   ?   A . n 
A 1 657 LYS 657 677 ?   ?   ?   A . n 
A 1 658 LYS 658 678 ?   ?   ?   A . n 
A 1 659 LYS 659 679 ?   ?   ?   A . n 
A 1 660 ILE 660 680 ?   ?   ?   A . n 
A 1 661 CYS 661 681 ?   ?   ?   A . n 
A 1 662 THR 662 682 ?   ?   ?   A . n 
A 1 663 LYS 663 683 ?   ?   ?   A . n 
A 1 664 LYS 664 684 ?   ?   ?   A . n 
A 1 665 PRO 665 685 ?   ?   ?   A . n 
A 1 666 ARG 666 686 ?   ?   ?   A . n 
A 1 667 PHE 667 687 ?   ?   ?   A . n 
A 1 668 MET 668 688 688 MET MET A . n 
A 1 669 SER 669 689 689 SER SER A . n 
A 1 670 ALA 670 690 690 ALA ALA A . n 
A 1 671 CYS 671 691 691 CYS CYS A . n 
A 1 672 ALA 672 692 692 ALA ALA A . n 
A 1 673 GLN 673 693 693 GLN GLN A . n 
A 1 674 LEU 674 694 694 LEU LEU A . n 
A 1 675 VAL 675 695 695 VAL VAL A . n 
A 1 676 ILE 676 696 696 ILE ILE A . n 
A 1 677 ALA 677 697 697 ALA ALA A . n 
A 1 678 PHE 678 698 698 PHE PHE A . n 
A 1 679 ILE 679 699 699 ILE ILE A . n 
A 1 680 LEU 680 700 700 LEU LEU A . n 
A 1 681 ILE 681 701 701 ILE ILE A . n 
A 1 682 CYS 682 702 702 CYS CYS A . n 
A 1 683 ILE 683 703 703 ILE ILE A . n 
A 1 684 GLN 684 704 704 GLN GLN A . n 
A 1 685 LEU 685 705 705 LEU LEU A . n 
A 1 686 GLY 686 706 706 GLY GLY A . n 
A 1 687 ILE 687 707 707 ILE ILE A . n 
A 1 688 ILE 688 708 708 ILE ILE A . n 
A 1 689 VAL 689 709 709 VAL VAL A . n 
A 1 690 ALA 690 710 710 ALA ALA A . n 
A 1 691 LEU 691 711 711 LEU LEU A . n 
A 1 692 PHE 692 712 712 PHE PHE A . n 
A 1 693 ILE 693 713 713 ILE ILE A . n 
A 1 694 MET 694 714 714 MET MET A . n 
A 1 695 GLU 695 715 715 GLU GLU A . n 
A 1 696 PRO 696 716 716 PRO PRO A . n 
A 1 697 PRO 697 717 717 PRO PRO A . n 
A 1 698 ASP 698 718 718 ASP ASP A . n 
A 1 699 ILE 699 719 719 ILE ILE A . n 
A 1 700 MET 700 720 720 MET MET A . n 
A 1 701 HIS 701 721 721 HIS HIS A . n 
A 1 702 ASP 702 722 722 ASP ASP A . n 
A 1 703 TYR 703 723 723 TYR TYR A . n 
A 1 704 PRO 704 724 724 PRO PRO A . n 
A 1 705 SER 705 725 725 SER SER A . n 
A 1 706 ILE 706 726 726 ILE ILE A . n 
A 1 707 ARG 707 727 727 ARG ARG A . n 
A 1 708 GLU 708 728 728 GLU GLU A . n 
A 1 709 VAL 709 729 729 VAL VAL A . n 
A 1 710 TYR 710 730 730 TYR TYR A . n 
A 1 711 LEU 711 731 731 LEU LEU A . n 
A 1 712 ILE 712 732 732 ILE ILE A . n 
A 1 713 CYS 713 733 733 CYS CYS A . n 
A 1 714 ASN 714 734 734 ASN ASN A . n 
A 1 715 THR 715 735 735 THR THR A . n 
A 1 716 THR 716 736 736 THR THR A . n 
A 1 717 ASN 717 737 737 ASN ASN A . n 
A 1 718 LEU 718 738 738 LEU LEU A . n 
A 1 719 GLY 719 739 739 GLY GLY A . n 
A 1 720 VAL 720 740 740 VAL VAL A . n 
A 1 721 VAL 721 741 741 VAL VAL A . n 
A 1 722 ALA 722 742 742 ALA ALA A . n 
A 1 723 PRO 723 743 743 PRO PRO A . n 
A 1 724 LEU 724 744 744 LEU LEU A . n 
A 1 725 GLY 725 745 745 GLY GLY A . n 
A 1 726 TYR 726 746 746 TYR TYR A . n 
A 1 727 ASN 727 747 747 ASN ASN A . n 
A 1 728 GLY 728 748 748 GLY GLY A . n 
A 1 729 LEU 729 749 749 LEU LEU A . n 
A 1 730 LEU 730 750 750 LEU LEU A . n 
A 1 731 ILE 731 751 751 ILE ILE A . n 
A 1 732 LEU 732 752 752 LEU LEU A . n 
A 1 733 ALA 733 753 753 ALA ALA A . n 
A 1 734 CYS 734 754 754 CYS CYS A . n 
A 1 735 THR 735 755 755 THR THR A . n 
A 1 736 PHE 736 756 756 PHE PHE A . n 
A 1 737 TYR 737 757 757 TYR TYR A . n 
A 1 738 ALA 738 758 758 ALA ALA A . n 
A 1 739 PHE 739 759 759 PHE PHE A . n 
A 1 740 LYS 740 760 760 LYS LYS A . n 
A 1 741 THR 741 761 761 THR THR A . n 
A 1 742 ARG 742 762 762 ARG ARG A . n 
A 1 743 ASN 743 763 763 ASN ASN A . n 
A 1 744 VAL 744 764 764 VAL VAL A . n 
A 1 745 PRO 745 765 765 PRO PRO A . n 
A 1 746 ALA 746 766 766 ALA ALA A . n 
A 1 747 ASN 747 767 767 ASN ASN A . n 
A 1 748 PHE 748 768 768 PHE PHE A . n 
A 1 749 ASN 749 769 769 ASN ASN A . n 
A 1 750 GLU 750 770 770 GLU GLU A . n 
A 1 751 ALA 751 771 771 ALA ALA A . n 
A 1 752 LYS 752 772 772 LYS LYS A . n 
A 1 753 TYR 753 773 773 TYR TYR A . n 
A 1 754 ILE 754 774 774 ILE ILE A . n 
A 1 755 ALA 755 775 775 ALA ALA A . n 
A 1 756 PHE 756 776 776 PHE PHE A . n 
A 1 757 ALA 757 777 777 ALA ALA A . n 
A 1 758 MET 758 778 778 MET MET A . n 
A 1 759 TYR 759 779 779 TYR TYR A . n 
A 1 760 THR 760 780 780 THR THR A . n 
A 1 761 THR 761 781 781 THR THR A . n 
A 1 762 CYS 762 782 782 CYS CYS A . n 
A 1 763 ILE 763 783 783 ILE ILE A . n 
A 1 764 ILE 764 784 784 ILE ILE A . n 
A 1 765 TRP 765 785 785 TRP TRP A . n 
A 1 766 LEU 766 786 786 LEU LEU A . n 
A 1 767 ALA 767 787 787 ALA ALA A . n 
A 1 768 PHE 768 788 788 PHE PHE A . n 
A 1 769 VAL 769 789 789 VAL VAL A . n 
A 1 770 PRO 770 790 790 PRO PRO A . n 
A 1 771 ILE 771 791 791 ILE ILE A . n 
A 1 772 TYR 772 792 792 TYR TYR A . n 
A 1 773 PHE 773 793 793 PHE PHE A . n 
A 1 774 GLY 774 794 794 GLY GLY A . n 
A 1 775 SER 775 795 795 SER SER A . n 
A 1 776 ASN 776 796 796 ASN ASN A . n 
A 1 777 TYR 777 797 797 TYR TYR A . n 
A 1 778 LYS 778 798 798 LYS LYS A . n 
A 1 779 ALA 779 799 799 ALA ALA A . n 
A 1 780 ILE 780 800 800 ILE ILE A . n 
A 1 781 THR 781 801 801 THR THR A . n 
A 1 782 MET 782 802 802 MET MET A . n 
A 1 783 CYS 783 803 803 CYS CYS A . n 
A 1 784 PHE 784 804 804 PHE PHE A . n 
A 1 785 SER 785 805 805 SER SER A . n 
A 1 786 VAL 786 806 806 VAL VAL A . n 
A 1 787 SER 787 807 807 SER SER A . n 
A 1 788 LEU 788 808 808 LEU LEU A . n 
A 1 789 SER 789 809 809 SER SER A . n 
A 1 790 ALA 790 810 810 ALA ALA A . n 
A 1 791 THR 791 811 811 THR THR A . n 
A 1 792 VAL 792 812 812 VAL VAL A . n 
A 1 793 LEU 793 813 813 LEU LEU A . n 
A 1 794 LEU 794 814 814 LEU LEU A . n 
A 1 795 GLY 795 815 815 GLY GLY A . n 
A 1 796 CYS 796 816 816 CYS CYS A . n 
A 1 797 MET 797 817 817 MET MET A . n 
A 1 798 PHE 798 818 818 PHE PHE A . n 
A 1 799 VAL 799 819 819 VAL VAL A . n 
A 1 800 PRO 800 820 820 PRO PRO A . n 
A 1 801 LYS 801 821 821 LYS LYS A . n 
A 1 802 VAL 802 822 822 VAL VAL A . n 
A 1 803 TYR 803 823 823 TYR TYR A . n 
A 1 804 ILE 804 824 824 ILE ILE A . n 
A 1 805 ILE 805 825 825 ILE ILE A . n 
A 1 806 LEU 806 826 826 LEU LEU A . n 
A 1 807 ALA 807 827 827 ALA ALA A . n 
A 1 808 LYS 808 828 ?   ?   ?   A . n 
A 1 809 PRO 809 829 ?   ?   ?   A . n 
A 1 810 GLU 810 830 ?   ?   ?   A . n 
A 1 811 ARG 811 831 ?   ?   ?   A . n 
A 1 812 ASN 812 832 ?   ?   ?   A . n 
A 1 813 VAL 813 833 ?   ?   ?   A . n 
A 1 814 ARG 814 834 ?   ?   ?   A . n 
A 1 815 SER 815 835 ?   ?   ?   A . n 
A 1 816 ALA 816 836 ?   ?   ?   A . n 
A 1 817 PHE 817 837 ?   ?   ?   A . n 
A 1 818 THR 818 838 ?   ?   ?   A . n 
A 1 819 THR 819 839 ?   ?   ?   A . n 
A 1 820 SER 820 840 ?   ?   ?   A . n 
A 1 821 THR 821 841 ?   ?   ?   A . n 
A 1 822 VAL 822 842 ?   ?   ?   A . n 
A 1 823 VAL 823 843 ?   ?   ?   A . n 
A 1 824 ARG 824 844 ?   ?   ?   A . n 
A 1 825 MET 825 845 ?   ?   ?   A . n 
A 1 826 HIS 826 846 ?   ?   ?   A . n 
A 1 827 VAL 827 847 ?   ?   ?   A . n 
A 1 828 GLY 828 848 ?   ?   ?   A . n 
A 1 829 ASP 829 849 ?   ?   ?   A . n 
A 1 830 GLY 830 850 ?   ?   ?   A . n 
A 1 831 LYS 831 851 ?   ?   ?   A . n 
A 1 832 SER 832 852 ?   ?   ?   A . n 
A 1 833 SER 833 853 ?   ?   ?   A . n 
A 1 834 SER 834 854 ?   ?   ?   A . n 
A 1 835 ALA 835 855 ?   ?   ?   A . n 
A 1 836 ALA 836 856 ?   ?   ?   A . n 
B 1 1   GLN 1   21  ?   ?   ?   B . n 
B 1 2   SER 2   22  ?   ?   ?   B . n 
B 1 3   SER 3   23  ?   ?   ?   B . n 
B 1 4   GLU 4   24  ?   ?   ?   B . n 
B 1 5   ARG 5   25  25  ARG ARG B . n 
B 1 6   ARG 6   26  26  ARG ARG B . n 
B 1 7   VAL 7   27  27  VAL VAL B . n 
B 1 8   VAL 8   28  28  VAL VAL B . n 
B 1 9   ALA 9   29  29  ALA ALA B . n 
B 1 10  HIS 10  30  30  HIS HIS B . n 
B 1 11  MET 11  31  31  MET MET B . n 
B 1 12  PRO 12  32  32  PRO PRO B . n 
B 1 13  GLY 13  33  33  GLY GLY B . n 
B 1 14  ASP 14  34  34  ASP ASP B . n 
B 1 15  ILE 15  35  35  ILE ILE B . n 
B 1 16  ILE 16  36  36  ILE ILE B . n 
B 1 17  ILE 17  37  37  ILE ILE B . n 
B 1 18  GLY 18  38  38  GLY GLY B . n 
B 1 19  ALA 19  39  39  ALA ALA B . n 
B 1 20  LEU 20  40  40  LEU LEU B . n 
B 1 21  PHE 21  41  41  PHE PHE B . n 
B 1 22  SER 22  42  42  SER SER B . n 
B 1 23  VAL 23  43  43  VAL VAL B . n 
B 1 24  HIS 24  44  44  HIS HIS B . n 
B 1 25  HIS 25  45  45  HIS HIS B . n 
B 1 26  GLN 26  46  46  GLN GLN B . n 
B 1 27  PRO 27  47  47  PRO PRO B . n 
B 1 28  THR 28  48  48  THR THR B . n 
B 1 29  VAL 29  49  49  VAL VAL B . n 
B 1 30  ASP 30  50  50  ASP ASP B . n 
B 1 31  LYS 31  51  51  LYS LYS B . n 
B 1 32  VAL 32  52  52  VAL VAL B . n 
B 1 33  HIS 33  53  53  HIS HIS B . n 
B 1 34  GLU 34  54  54  GLU GLU B . n 
B 1 35  ARG 35  55  55  ARG ARG B . n 
B 1 36  LYS 36  56  56  LYS LYS B . n 
B 1 37  CYS 37  57  57  CYS CYS B . n 
B 1 38  GLY 38  58  58  GLY GLY B . n 
B 1 39  ALA 39  59  59  ALA ALA B . n 
B 1 40  VAL 40  60  60  VAL VAL B . n 
B 1 41  ARG 41  61  61  ARG ARG B . n 
B 1 42  GLU 42  62  62  GLU GLU B . n 
B 1 43  GLN 43  63  63  GLN GLN B . n 
B 1 44  TYR 44  64  64  TYR TYR B . n 
B 1 45  GLY 45  65  65  GLY GLY B . n 
B 1 46  ILE 46  66  66  ILE ILE B . n 
B 1 47  GLN 47  67  67  GLN GLN B . n 
B 1 48  ARG 48  68  68  ARG ARG B . n 
B 1 49  VAL 49  69  69  VAL VAL B . n 
B 1 50  GLU 50  70  70  GLU GLU B . n 
B 1 51  ALA 51  71  71  ALA ALA B . n 
B 1 52  MET 52  72  72  MET MET B . n 
B 1 53  LEU 53  73  73  LEU LEU B . n 
B 1 54  HIS 54  74  74  HIS HIS B . n 
B 1 55  THR 55  75  75  THR THR B . n 
B 1 56  LEU 56  76  76  LEU LEU B . n 
B 1 57  GLU 57  77  77  GLU GLU B . n 
B 1 58  ARG 58  78  78  ARG ARG B . n 
B 1 59  ILE 59  79  79  ILE ILE B . n 
B 1 60  ASN 60  80  80  ASN ASN B . n 
B 1 61  SER 61  81  81  SER SER B . n 
B 1 62  ASP 62  82  82  ASP ASP B . n 
B 1 63  PRO 63  83  83  PRO PRO B . n 
B 1 64  THR 64  84  84  THR THR B . n 
B 1 65  LEU 65  85  85  LEU LEU B . n 
B 1 66  LEU 66  86  86  LEU LEU B . n 
B 1 67  PRO 67  87  87  PRO PRO B . n 
B 1 68  ASN 68  88  88  ASN ASN B . n 
B 1 69  ILE 69  89  89  ILE ILE B . n 
B 1 70  THR 70  90  90  THR THR B . n 
B 1 71  LEU 71  91  91  LEU LEU B . n 
B 1 72  GLY 72  92  92  GLY GLY B . n 
B 1 73  CYS 73  93  93  CYS CYS B . n 
B 1 74  GLU 74  94  94  GLU GLU B . n 
B 1 75  ILE 75  95  95  ILE ILE B . n 
B 1 76  ARG 76  96  96  ARG ARG B . n 
B 1 77  ASP 77  97  97  ASP ASP B . n 
B 1 78  SER 78  98  98  SER SER B . n 
B 1 79  CYS 79  99  99  CYS CYS B . n 
B 1 80  TRP 80  100 100 TRP TRP B . n 
B 1 81  HIS 81  101 101 HIS HIS B . n 
B 1 82  SER 82  102 102 SER SER B . n 
B 1 83  ALA 83  103 103 ALA ALA B . n 
B 1 84  VAL 84  104 104 VAL VAL B . n 
B 1 85  ALA 85  105 105 ALA ALA B . n 
B 1 86  LEU 86  106 106 LEU LEU B . n 
B 1 87  GLU 87  107 107 GLU GLU B . n 
B 1 88  GLN 88  108 108 GLN GLN B . n 
B 1 89  SER 89  109 109 SER SER B . n 
B 1 90  ILE 90  110 110 ILE ILE B . n 
B 1 91  GLU 91  111 111 GLU GLU B . n 
B 1 92  PHE 92  112 112 PHE PHE B . n 
B 1 93  ILE 93  113 113 ILE ILE B . n 
B 1 94  ARG 94  114 114 ARG ARG B . n 
B 1 95  ASP 95  115 115 ASP ASP B . n 
B 1 96  SER 96  116 116 SER SER B . n 
B 1 97  LEU 97  117 117 LEU LEU B . n 
B 1 98  ILE 98  118 ?   ?   ?   B . n 
B 1 99  SER 99  119 ?   ?   ?   B . n 
B 1 100 SER 100 120 ?   ?   ?   B . n 
B 1 101 GLU 101 121 ?   ?   ?   B . n 
B 1 102 GLU 102 122 ?   ?   ?   B . n 
B 1 103 GLU 103 123 ?   ?   ?   B . n 
B 1 104 GLU 104 124 ?   ?   ?   B . n 
B 1 105 GLY 105 125 ?   ?   ?   B . n 
B 1 106 LEU 106 126 ?   ?   ?   B . n 
B 1 107 VAL 107 127 ?   ?   ?   B . n 
B 1 108 ARG 108 128 ?   ?   ?   B . n 
B 1 109 CYS 109 129 ?   ?   ?   B . n 
B 1 110 VAL 110 130 ?   ?   ?   B . n 
B 1 111 ASP 111 131 ?   ?   ?   B . n 
B 1 112 GLY 112 132 ?   ?   ?   B . n 
B 1 113 SER 113 133 ?   ?   ?   B . n 
B 1 114 SER 114 134 ?   ?   ?   B . n 
B 1 115 SER 115 135 ?   ?   ?   B . n 
B 1 116 SER 116 136 ?   ?   ?   B . n 
B 1 117 PHE 117 137 ?   ?   ?   B . n 
B 1 118 ARG 118 138 ?   ?   ?   B . n 
B 1 119 SER 119 139 ?   ?   ?   B . n 
B 1 120 LYS 120 140 ?   ?   ?   B . n 
B 1 121 LYS 121 141 141 LYS LYS B . n 
B 1 122 PRO 122 142 142 PRO PRO B . n 
B 1 123 ILE 123 143 143 ILE ILE B . n 
B 1 124 VAL 124 144 144 VAL VAL B . n 
B 1 125 GLY 125 145 145 GLY GLY B . n 
B 1 126 VAL 126 146 146 VAL VAL B . n 
B 1 127 ILE 127 147 147 ILE ILE B . n 
B 1 128 GLY 128 148 148 GLY GLY B . n 
B 1 129 PRO 129 149 149 PRO PRO B . n 
B 1 130 GLY 130 150 150 GLY GLY B . n 
B 1 131 SER 131 151 151 SER SER B . n 
B 1 132 SER 132 152 152 SER SER B . n 
B 1 133 SER 133 153 153 SER SER B . n 
B 1 134 VAL 134 154 154 VAL VAL B . n 
B 1 135 ALA 135 155 155 ALA ALA B . n 
B 1 136 ILE 136 156 156 ILE ILE B . n 
B 1 137 GLN 137 157 157 GLN GLN B . n 
B 1 138 VAL 138 158 158 VAL VAL B . n 
B 1 139 GLN 139 159 159 GLN GLN B . n 
B 1 140 ASN 140 160 160 ASN ASN B . n 
B 1 141 LEU 141 161 161 LEU LEU B . n 
B 1 142 LEU 142 162 162 LEU LEU B . n 
B 1 143 GLN 143 163 163 GLN GLN B . n 
B 1 144 LEU 144 164 164 LEU LEU B . n 
B 1 145 PHE 145 165 165 PHE PHE B . n 
B 1 146 ASN 146 166 166 ASN ASN B . n 
B 1 147 ILE 147 167 167 ILE ILE B . n 
B 1 148 PRO 148 168 168 PRO PRO B . n 
B 1 149 GLN 149 169 169 GLN GLN B . n 
B 1 150 ILE 150 170 170 ILE ILE B . n 
B 1 151 ALA 151 171 171 ALA ALA B . n 
B 1 152 TYR 152 172 172 TYR TYR B . n 
B 1 153 SER 153 173 173 SER SER B . n 
B 1 154 ALA 154 174 174 ALA ALA B . n 
B 1 155 THR 155 175 175 THR THR B . n 
B 1 156 SER 156 176 176 SER SER B . n 
B 1 157 MET 157 177 177 MET MET B . n 
B 1 158 ASP 158 178 178 ASP ASP B . n 
B 1 159 LEU 159 179 179 LEU LEU B . n 
B 1 160 SER 160 180 180 SER SER B . n 
B 1 161 ASP 161 181 181 ASP ASP B . n 
B 1 162 LYS 162 182 182 LYS LYS B . n 
B 1 163 THR 163 183 183 THR THR B . n 
B 1 164 LEU 164 184 184 LEU LEU B . n 
B 1 165 PHE 165 185 185 PHE PHE B . n 
B 1 166 LYS 166 186 186 LYS LYS B . n 
B 1 167 TYR 167 187 187 TYR TYR B . n 
B 1 168 PHE 168 188 188 PHE PHE B . n 
B 1 169 MET 169 189 189 MET MET B . n 
B 1 170 ARG 170 190 190 ARG ARG B . n 
B 1 171 VAL 171 191 191 VAL VAL B . n 
B 1 172 VAL 172 192 192 VAL VAL B . n 
B 1 173 PRO 173 193 193 PRO PRO B . n 
B 1 174 SER 174 194 194 SER SER B . n 
B 1 175 ASP 175 195 195 ASP ASP B . n 
B 1 176 ALA 176 196 196 ALA ALA B . n 
B 1 177 GLN 177 197 197 GLN GLN B . n 
B 1 178 GLN 178 198 198 GLN GLN B . n 
B 1 179 ALA 179 199 199 ALA ALA B . n 
B 1 180 ARG 180 200 200 ARG ARG B . n 
B 1 181 ALA 181 201 201 ALA ALA B . n 
B 1 182 MET 182 202 202 MET MET B . n 
B 1 183 VAL 183 203 203 VAL VAL B . n 
B 1 184 ASP 184 204 204 ASP ASP B . n 
B 1 185 ILE 185 205 205 ILE ILE B . n 
B 1 186 VAL 186 206 206 VAL VAL B . n 
B 1 187 LYS 187 207 207 LYS LYS B . n 
B 1 188 ARG 188 208 208 ARG ARG B . n 
B 1 189 TYR 189 209 209 TYR TYR B . n 
B 1 190 ASN 190 210 210 ASN ASN B . n 
B 1 191 TRP 191 211 211 TRP TRP B . n 
B 1 192 THR 192 212 212 THR THR B . n 
B 1 193 TYR 193 213 213 TYR TYR B . n 
B 1 194 VAL 194 214 214 VAL VAL B . n 
B 1 195 SER 195 215 215 SER SER B . n 
B 1 196 ALA 196 216 216 ALA ALA B . n 
B 1 197 VAL 197 217 217 VAL VAL B . n 
B 1 198 HIS 198 218 218 HIS HIS B . n 
B 1 199 THR 199 219 219 THR THR B . n 
B 1 200 GLU 200 220 220 GLU GLU B . n 
B 1 201 GLY 201 221 221 GLY GLY B . n 
B 1 202 ASN 202 222 222 ASN ASN B . n 
B 1 203 TYR 203 223 223 TYR TYR B . n 
B 1 204 GLY 204 224 224 GLY GLY B . n 
B 1 205 GLU 205 225 225 GLU GLU B . n 
B 1 206 SER 206 226 226 SER SER B . n 
B 1 207 GLY 207 227 227 GLY GLY B . n 
B 1 208 MET 208 228 228 MET MET B . n 
B 1 209 GLU 209 229 229 GLU GLU B . n 
B 1 210 ALA 210 230 230 ALA ALA B . n 
B 1 211 PHE 211 231 231 PHE PHE B . n 
B 1 212 LYS 212 232 232 LYS LYS B . n 
B 1 213 ASP 213 233 233 ASP ASP B . n 
B 1 214 MET 214 234 234 MET MET B . n 
B 1 215 SER 215 235 235 SER SER B . n 
B 1 216 ALA 216 236 236 ALA ALA B . n 
B 1 217 LYS 217 237 237 LYS LYS B . n 
B 1 218 GLU 218 238 238 GLU GLU B . n 
B 1 219 GLY 219 239 239 GLY GLY B . n 
B 1 220 ILE 220 240 240 ILE ILE B . n 
B 1 221 CYS 221 241 241 CYS CYS B . n 
B 1 222 ILE 222 242 242 ILE ILE B . n 
B 1 223 ALA 223 243 243 ALA ALA B . n 
B 1 224 HIS 224 244 244 HIS HIS B . n 
B 1 225 SER 225 245 245 SER SER B . n 
B 1 226 TYR 226 246 246 TYR TYR B . n 
B 1 227 LYS 227 247 247 LYS LYS B . n 
B 1 228 ILE 228 248 248 ILE ILE B . n 
B 1 229 TYR 229 249 249 TYR TYR B . n 
B 1 230 SER 230 250 250 SER SER B . n 
B 1 231 ASN 231 251 251 ASN ASN B . n 
B 1 232 ALA 232 252 252 ALA ALA B . n 
B 1 233 GLY 233 253 253 GLY GLY B . n 
B 1 234 GLU 234 254 254 GLU GLU B . n 
B 1 235 GLN 235 255 255 GLN GLN B . n 
B 1 236 SER 236 256 256 SER SER B . n 
B 1 237 PHE 237 257 257 PHE PHE B . n 
B 1 238 ASP 238 258 258 ASP ASP B . n 
B 1 239 LYS 239 259 259 LYS LYS B . n 
B 1 240 LEU 240 260 260 LEU LEU B . n 
B 1 241 LEU 241 261 261 LEU LEU B . n 
B 1 242 LYS 242 262 262 LYS LYS B . n 
B 1 243 LYS 243 263 263 LYS LYS B . n 
B 1 244 LEU 244 264 264 LEU LEU B . n 
B 1 245 THR 245 265 265 THR THR B . n 
B 1 246 SER 246 266 266 SER SER B . n 
B 1 247 HIS 247 267 267 HIS HIS B . n 
B 1 248 LEU 248 268 268 LEU LEU B . n 
B 1 249 PRO 249 269 269 PRO PRO B . n 
B 1 250 LYS 250 270 270 LYS LYS B . n 
B 1 251 ALA 251 271 271 ALA ALA B . n 
B 1 252 ARG 252 272 272 ARG ARG B . n 
B 1 253 VAL 253 273 273 VAL VAL B . n 
B 1 254 VAL 254 274 274 VAL VAL B . n 
B 1 255 ALA 255 275 275 ALA ALA B . n 
B 1 256 CYS 256 276 276 CYS CYS B . n 
B 1 257 PHE 257 277 277 PHE PHE B . n 
B 1 258 CYS 258 278 278 CYS CYS B . n 
B 1 259 GLU 259 279 279 GLU GLU B . n 
B 1 260 GLY 260 280 280 GLY GLY B . n 
B 1 261 MET 261 281 281 MET MET B . n 
B 1 262 THR 262 282 282 THR THR B . n 
B 1 263 VAL 263 283 283 VAL VAL B . n 
B 1 264 ARG 264 284 284 ARG ARG B . n 
B 1 265 GLY 265 285 285 GLY GLY B . n 
B 1 266 LEU 266 286 286 LEU LEU B . n 
B 1 267 LEU 267 287 287 LEU LEU B . n 
B 1 268 MET 268 288 288 MET MET B . n 
B 1 269 ALA 269 289 289 ALA ALA B . n 
B 1 270 MET 270 290 290 MET MET B . n 
B 1 271 ARG 271 291 291 ARG ARG B . n 
B 1 272 ARG 272 292 292 ARG ARG B . n 
B 1 273 LEU 273 293 293 LEU LEU B . n 
B 1 274 GLY 274 294 294 GLY GLY B . n 
B 1 275 LEU 275 295 295 LEU LEU B . n 
B 1 276 ALA 276 296 296 ALA ALA B . n 
B 1 277 GLY 277 297 297 GLY GLY B . n 
B 1 278 GLU 278 298 298 GLU GLU B . n 
B 1 279 PHE 279 299 299 PHE PHE B . n 
B 1 280 LEU 280 300 300 LEU LEU B . n 
B 1 281 LEU 281 301 301 LEU LEU B . n 
B 1 282 LEU 282 302 302 LEU LEU B . n 
B 1 283 GLY 283 303 303 GLY GLY B . n 
B 1 284 SER 284 304 304 SER SER B . n 
B 1 285 ASP 285 305 305 ASP ASP B . n 
B 1 286 GLY 286 306 306 GLY GLY B . n 
B 1 287 TRP 287 307 307 TRP TRP B . n 
B 1 288 ALA 288 308 308 ALA ALA B . n 
B 1 289 ASP 289 309 309 ASP ASP B . n 
B 1 290 ARG 290 310 310 ARG ARG B . n 
B 1 291 TYR 291 311 311 TYR TYR B . n 
B 1 292 ASP 292 312 312 ASP ASP B . n 
B 1 293 VAL 293 313 313 VAL VAL B . n 
B 1 294 THR 294 314 314 THR THR B . n 
B 1 295 ASP 295 315 315 ASP ASP B . n 
B 1 296 GLY 296 316 316 GLY GLY B . n 
B 1 297 TYR 297 317 317 TYR TYR B . n 
B 1 298 GLN 298 318 318 GLN GLN B . n 
B 1 299 ARG 299 319 319 ARG ARG B . n 
B 1 300 GLU 300 320 320 GLU GLU B . n 
B 1 301 ALA 301 321 321 ALA ALA B . n 
B 1 302 VAL 302 322 322 VAL VAL B . n 
B 1 303 GLY 303 323 323 GLY GLY B . n 
B 1 304 GLY 304 324 324 GLY GLY B . n 
B 1 305 ILE 305 325 325 ILE ILE B . n 
B 1 306 THR 306 326 326 THR THR B . n 
B 1 307 ILE 307 327 327 ILE ILE B . n 
B 1 308 LYS 308 328 328 LYS LYS B . n 
B 1 309 LEU 309 329 329 LEU LEU B . n 
B 1 310 GLN 310 330 330 GLN GLN B . n 
B 1 311 SER 311 331 331 SER SER B . n 
B 1 312 PRO 312 332 332 PRO PRO B . n 
B 1 313 ASP 313 333 333 ASP ASP B . n 
B 1 314 VAL 314 334 334 VAL VAL B . n 
B 1 315 LYS 315 335 335 LYS LYS B . n 
B 1 316 TRP 316 336 336 TRP TRP B . n 
B 1 317 PHE 317 337 337 PHE PHE B . n 
B 1 318 ASP 318 338 338 ASP ASP B . n 
B 1 319 ASP 319 339 339 ASP ASP B . n 
B 1 320 TYR 320 340 340 TYR TYR B . n 
B 1 321 TYR 321 341 341 TYR TYR B . n 
B 1 322 LEU 322 342 342 LEU LEU B . n 
B 1 323 LYS 323 343 343 LYS LYS B . n 
B 1 324 LEU 324 344 344 LEU LEU B . n 
B 1 325 ARG 325 345 345 ARG ARG B . n 
B 1 326 PRO 326 346 346 PRO PRO B . n 
B 1 327 GLU 327 347 347 GLU GLU B . n 
B 1 328 THR 328 348 348 THR THR B . n 
B 1 329 ASN 329 349 349 ASN ASN B . n 
B 1 330 LEU 330 350 350 LEU LEU B . n 
B 1 331 ARG 331 351 351 ARG ARG B . n 
B 1 332 ASN 332 352 352 ASN ASN B . n 
B 1 333 PRO 333 353 353 PRO PRO B . n 
B 1 334 TRP 334 354 354 TRP TRP B . n 
B 1 335 PHE 335 355 355 PHE PHE B . n 
B 1 336 GLN 336 356 356 GLN GLN B . n 
B 1 337 GLU 337 357 357 GLU GLU B . n 
B 1 338 PHE 338 358 358 PHE PHE B . n 
B 1 339 TRP 339 359 359 TRP TRP B . n 
B 1 340 GLN 340 360 360 GLN GLN B . n 
B 1 341 HIS 341 361 361 HIS HIS B . n 
B 1 342 ARG 342 362 362 ARG ARG B . n 
B 1 343 PHE 343 363 363 PHE PHE B . n 
B 1 344 GLN 344 364 364 GLN GLN B . n 
B 1 345 CYS 345 365 365 CYS CYS B . n 
B 1 346 ARG 346 366 366 ARG ARG B . n 
B 1 347 LEU 347 367 367 LEU LEU B . n 
B 1 348 GLU 348 368 368 GLU GLU B . n 
B 1 349 GLY 349 369 369 GLY GLY B . n 
B 1 350 PHE 350 370 370 PHE PHE B . n 
B 1 351 PRO 351 371 371 PRO PRO B . n 
B 1 352 GLN 352 372 372 GLN GLN B . n 
B 1 353 GLU 353 373 373 GLU GLU B . n 
B 1 354 ASN 354 374 374 ASN ASN B . n 
B 1 355 SER 355 375 375 SER SER B . n 
B 1 356 LYS 356 376 376 LYS LYS B . n 
B 1 357 TYR 357 377 377 TYR TYR B . n 
B 1 358 ASN 358 378 378 ASN ASN B . n 
B 1 359 LYS 359 379 379 LYS LYS B . n 
B 1 360 THR 360 380 380 THR THR B . n 
B 1 361 CYS 361 381 381 CYS CYS B . n 
B 1 362 ASN 362 382 382 ASN ASN B . n 
B 1 363 SER 363 383 383 SER SER B . n 
B 1 364 SER 364 384 384 SER SER B . n 
B 1 365 LEU 365 385 385 LEU LEU B . n 
B 1 366 THR 366 386 386 THR THR B . n 
B 1 367 LEU 367 387 387 LEU LEU B . n 
B 1 368 LYS 368 388 388 LYS LYS B . n 
B 1 369 THR 369 389 389 THR THR B . n 
B 1 370 HIS 370 390 390 HIS HIS B . n 
B 1 371 HIS 371 391 391 HIS HIS B . n 
B 1 372 VAL 372 392 392 VAL VAL B . n 
B 1 373 GLN 373 393 393 GLN GLN B . n 
B 1 374 ASP 374 394 394 ASP ASP B . n 
B 1 375 SER 375 395 395 SER SER B . n 
B 1 376 LYS 376 396 396 LYS LYS B . n 
B 1 377 MET 377 397 397 MET MET B . n 
B 1 378 GLY 378 398 398 GLY GLY B . n 
B 1 379 PHE 379 399 399 PHE PHE B . n 
B 1 380 VAL 380 400 400 VAL VAL B . n 
B 1 381 ILE 381 401 401 ILE ILE B . n 
B 1 382 ASN 382 402 402 ASN ASN B . n 
B 1 383 ALA 383 403 403 ALA ALA B . n 
B 1 384 ILE 384 404 404 ILE ILE B . n 
B 1 385 TYR 385 405 405 TYR TYR B . n 
B 1 386 SER 386 406 406 SER SER B . n 
B 1 387 MET 387 407 407 MET MET B . n 
B 1 388 ALA 388 408 408 ALA ALA B . n 
B 1 389 TYR 389 409 409 TYR TYR B . n 
B 1 390 GLY 390 410 410 GLY GLY B . n 
B 1 391 LEU 391 411 411 LEU LEU B . n 
B 1 392 HIS 392 412 412 HIS HIS B . n 
B 1 393 ASN 393 413 413 ASN ASN B . n 
B 1 394 MET 394 414 414 MET MET B . n 
B 1 395 GLN 395 415 415 GLN GLN B . n 
B 1 396 MET 396 416 416 MET MET B . n 
B 1 397 SER 397 417 417 SER SER B . n 
B 1 398 LEU 398 418 418 LEU LEU B . n 
B 1 399 CYS 399 419 419 CYS CYS B . n 
B 1 400 PRO 400 420 420 PRO PRO B . n 
B 1 401 GLY 401 421 421 GLY GLY B . n 
B 1 402 TYR 402 422 422 TYR TYR B . n 
B 1 403 ALA 403 423 423 ALA ALA B . n 
B 1 404 GLY 404 424 424 GLY GLY B . n 
B 1 405 LEU 405 425 425 LEU LEU B . n 
B 1 406 CYS 406 426 426 CYS CYS B . n 
B 1 407 ASP 407 427 427 ASP ASP B . n 
B 1 408 ALA 408 428 428 ALA ALA B . n 
B 1 409 MET 409 429 429 MET MET B . n 
B 1 410 LYS 410 430 430 LYS LYS B . n 
B 1 411 PRO 411 431 431 PRO PRO B . n 
B 1 412 ILE 412 432 432 ILE ILE B . n 
B 1 413 ASP 413 433 433 ASP ASP B . n 
B 1 414 GLY 414 434 434 GLY GLY B . n 
B 1 415 ARG 415 435 435 ARG ARG B . n 
B 1 416 LYS 416 436 436 LYS LYS B . n 
B 1 417 LEU 417 437 437 LEU LEU B . n 
B 1 418 LEU 418 438 438 LEU LEU B . n 
B 1 419 GLU 419 439 439 GLU GLU B . n 
B 1 420 SER 420 440 440 SER SER B . n 
B 1 421 LEU 421 441 441 LEU LEU B . n 
B 1 422 MET 422 442 442 MET MET B . n 
B 1 423 LYS 423 443 443 LYS LYS B . n 
B 1 424 THR 424 444 444 THR THR B . n 
B 1 425 ALA 425 445 445 ALA ALA B . n 
B 1 426 PHE 426 446 446 PHE PHE B . n 
B 1 427 THR 427 447 447 THR THR B . n 
B 1 428 GLY 428 448 448 GLY GLY B . n 
B 1 429 VAL 429 449 449 VAL VAL B . n 
B 1 430 SER 430 450 450 SER SER B . n 
B 1 431 GLY 431 451 451 GLY GLY B . n 
B 1 432 ASP 432 452 452 ASP ASP B . n 
B 1 433 THR 433 453 453 THR THR B . n 
B 1 434 ILE 434 454 454 ILE ILE B . n 
B 1 435 LEU 435 455 455 LEU LEU B . n 
B 1 436 PHE 436 456 456 PHE PHE B . n 
B 1 437 ASP 437 457 457 ASP ASP B . n 
B 1 438 GLU 438 458 458 GLU GLU B . n 
B 1 439 ASN 439 459 459 ASN ASN B . n 
B 1 440 GLY 440 460 460 GLY GLY B . n 
B 1 441 ASP 441 461 461 ASP ASP B . n 
B 1 442 SER 442 462 462 SER SER B . n 
B 1 443 PRO 443 463 463 PRO PRO B . n 
B 1 444 GLY 444 464 464 GLY GLY B . n 
B 1 445 ARG 445 465 465 ARG ARG B . n 
B 1 446 TYR 446 466 466 TYR TYR B . n 
B 1 447 GLU 447 467 467 GLU GLU B . n 
B 1 448 ILE 448 468 468 ILE ILE B . n 
B 1 449 MET 449 469 469 MET MET B . n 
B 1 450 ASN 450 470 470 ASN ASN B . n 
B 1 451 PHE 451 471 471 PHE PHE B . n 
B 1 452 LYS 452 472 472 LYS LYS B . n 
B 1 453 GLU 453 473 473 GLU GLU B . n 
B 1 454 MET 454 474 474 MET MET B . n 
B 1 455 GLY 455 475 475 GLY GLY B . n 
B 1 456 LYS 456 476 476 LYS LYS B . n 
B 1 457 ASP 457 477 477 ASP ASP B . n 
B 1 458 TYR 458 478 478 TYR TYR B . n 
B 1 459 PHE 459 479 479 PHE PHE B . n 
B 1 460 ASP 460 480 480 ASP ASP B . n 
B 1 461 TYR 461 481 481 TYR TYR B . n 
B 1 462 ILE 462 482 482 ILE ILE B . n 
B 1 463 ASN 463 483 483 ASN ASN B . n 
B 1 464 VAL 464 484 484 VAL VAL B . n 
B 1 465 GLY 465 485 485 GLY GLY B . n 
B 1 466 SER 466 486 486 SER SER B . n 
B 1 467 TRP 467 487 487 TRP TRP B . n 
B 1 468 ASP 468 488 488 ASP ASP B . n 
B 1 469 ASN 469 489 489 ASN ASN B . n 
B 1 470 GLY 470 490 490 GLY GLY B . n 
B 1 471 GLU 471 491 491 GLU GLU B . n 
B 1 472 LEU 472 492 492 LEU LEU B . n 
B 1 473 LYS 473 493 493 LYS LYS B . n 
B 1 474 MET 474 494 494 MET MET B . n 
B 1 475 ASP 475 495 495 ASP ASP B . n 
B 1 476 ASP 476 496 496 ASP ASP B . n 
B 1 477 ASP 477 497 497 ASP ASP B . n 
B 1 478 GLU 478 498 498 GLU GLU B . n 
B 1 479 VAL 479 499 499 VAL VAL B . n 
B 1 480 TRP 480 500 500 TRP TRP B . n 
B 1 481 SER 481 501 501 SER SER B . n 
B 1 482 LYS 482 502 502 LYS LYS B . n 
B 1 483 LYS 483 503 503 LYS LYS B . n 
B 1 484 SER 484 504 504 SER SER B . n 
B 1 485 ASN 485 505 505 ASN ASN B . n 
B 1 486 ILE 486 506 506 ILE ILE B . n 
B 1 487 ILE 487 507 507 ILE ILE B . n 
B 1 488 ARG 488 508 508 ARG ARG B . n 
B 1 489 SER 489 509 509 SER SER B . n 
B 1 490 VAL 490 510 510 VAL VAL B . n 
B 1 491 CYS 491 511 511 CYS CYS B . n 
B 1 492 SER 492 512 512 SER SER B . n 
B 1 493 GLU 493 513 513 GLU GLU B . n 
B 1 494 PRO 494 514 514 PRO PRO B . n 
B 1 495 CYS 495 515 515 CYS CYS B . n 
B 1 496 GLU 496 516 516 GLU GLU B . n 
B 1 497 LYS 497 517 517 LYS LYS B . n 
B 1 498 GLY 498 518 518 GLY GLY B . n 
B 1 499 GLN 499 519 519 GLN GLN B . n 
B 1 500 ILE 500 520 520 ILE ILE B . n 
B 1 501 LYS 501 521 521 LYS LYS B . n 
B 1 502 VAL 502 522 522 VAL VAL B . n 
B 1 503 ILE 503 523 523 ILE ILE B . n 
B 1 504 ARG 504 524 524 ARG ARG B . n 
B 1 505 LYS 505 525 525 LYS LYS B . n 
B 1 506 GLY 506 526 526 GLY GLY B . n 
B 1 507 GLU 507 527 527 GLU GLU B . n 
B 1 508 VAL 508 528 528 VAL VAL B . n 
B 1 509 SER 509 529 529 SER SER B . n 
B 1 510 CYS 510 530 530 CYS CYS B . n 
B 1 511 CYS 511 531 531 CYS CYS B . n 
B 1 512 TRP 512 532 532 TRP TRP B . n 
B 1 513 THR 513 533 533 THR THR B . n 
B 1 514 CYS 514 534 534 CYS CYS B . n 
B 1 515 THR 515 535 535 THR THR B . n 
B 1 516 PRO 516 536 536 PRO PRO B . n 
B 1 517 CYS 517 537 537 CYS CYS B . n 
B 1 518 LYS 518 538 538 LYS LYS B . n 
B 1 519 GLU 519 539 539 GLU GLU B . n 
B 1 520 ASN 520 540 540 ASN ASN B . n 
B 1 521 GLU 521 541 541 GLU GLU B . n 
B 1 522 TYR 522 542 542 TYR TYR B . n 
B 1 523 VAL 523 543 543 VAL VAL B . n 
B 1 524 PHE 524 544 544 PHE PHE B . n 
B 1 525 ASP 525 545 545 ASP ASP B . n 
B 1 526 GLU 526 546 546 GLU GLU B . n 
B 1 527 TYR 527 547 547 TYR TYR B . n 
B 1 528 THR 528 548 548 THR THR B . n 
B 1 529 CYS 529 549 549 CYS CYS B . n 
B 1 530 LYS 530 550 550 LYS LYS B . n 
B 1 531 ALA 531 551 551 ALA ALA B . n 
B 1 532 CYS 532 552 552 CYS CYS B . n 
B 1 533 GLN 533 553 553 GLN GLN B . n 
B 1 534 LEU 534 554 554 LEU LEU B . n 
B 1 535 GLY 535 555 555 GLY GLY B . n 
B 1 536 SER 536 556 556 SER SER B . n 
B 1 537 TRP 537 557 557 TRP TRP B . n 
B 1 538 PRO 538 558 558 PRO PRO B . n 
B 1 539 THR 539 559 559 THR THR B . n 
B 1 540 ASP 540 560 560 ASP ASP B . n 
B 1 541 ASP 541 561 561 ASP ASP B . n 
B 1 542 LEU 542 562 562 LEU LEU B . n 
B 1 543 THR 543 563 563 THR THR B . n 
B 1 544 GLY 544 564 564 GLY GLY B . n 
B 1 545 CYS 545 565 565 CYS CYS B . n 
B 1 546 ASP 546 566 566 ASP ASP B . n 
B 1 547 LEU 547 567 567 LEU LEU B . n 
B 1 548 ILE 548 568 568 ILE ILE B . n 
B 1 549 PRO 549 569 569 PRO PRO B . n 
B 1 550 VAL 550 570 570 VAL VAL B . n 
B 1 551 GLN 551 571 571 GLN GLN B . n 
B 1 552 TYR 552 572 572 TYR TYR B . n 
B 1 553 LEU 553 573 573 LEU LEU B . n 
B 1 554 ARG 554 574 574 ARG ARG B . n 
B 1 555 TRP 555 575 575 TRP TRP B . n 
B 1 556 GLY 556 576 576 GLY GLY B . n 
B 1 557 ASP 557 577 577 ASP ASP B . n 
B 1 558 PRO 558 578 578 PRO PRO B . n 
B 1 559 GLU 559 579 579 GLU GLU B . n 
B 1 560 PRO 560 580 580 PRO PRO B . n 
B 1 561 ILE 561 581 581 ILE ILE B . n 
B 1 562 ALA 562 582 582 ALA ALA B . n 
B 1 563 ALA 563 583 583 ALA ALA B . n 
B 1 564 VAL 564 584 584 VAL VAL B . n 
B 1 565 VAL 565 585 585 VAL VAL B . n 
B 1 566 PHE 566 586 586 PHE PHE B . n 
B 1 567 ALA 567 587 587 ALA ALA B . n 
B 1 568 CYS 568 588 588 CYS CYS B . n 
B 1 569 LEU 569 589 589 LEU LEU B . n 
B 1 570 GLY 570 590 590 GLY GLY B . n 
B 1 571 LEU 571 591 591 LEU LEU B . n 
B 1 572 LEU 572 592 592 LEU LEU B . n 
B 1 573 ALA 573 593 593 ALA ALA B . n 
B 1 574 THR 574 594 594 THR THR B . n 
B 1 575 LEU 575 595 595 LEU LEU B . n 
B 1 576 PHE 576 596 596 PHE PHE B . n 
B 1 577 VAL 577 597 597 VAL VAL B . n 
B 1 578 THR 578 598 598 THR THR B . n 
B 1 579 VAL 579 599 599 VAL VAL B . n 
B 1 580 VAL 580 600 600 VAL VAL B . n 
B 1 581 PHE 581 601 601 PHE PHE B . n 
B 1 582 ILE 582 602 602 ILE ILE B . n 
B 1 583 ILE 583 603 603 ILE ILE B . n 
B 1 584 TYR 584 604 604 TYR TYR B . n 
B 1 585 ARG 585 605 605 ARG ARG B . n 
B 1 586 ASP 586 606 606 ASP ASP B . n 
B 1 587 THR 587 607 607 THR THR B . n 
B 1 588 PRO 588 608 608 PRO PRO B . n 
B 1 589 VAL 589 609 609 VAL VAL B . n 
B 1 590 VAL 590 610 610 VAL VAL B . n 
B 1 591 LYS 591 611 611 LYS LYS B . n 
B 1 592 SER 592 612 612 SER SER B . n 
B 1 593 SER 593 613 613 SER SER B . n 
B 1 594 SER 594 614 614 SER SER B . n 
B 1 595 ARG 595 615 615 ARG ARG B . n 
B 1 596 GLU 596 616 616 GLU GLU B . n 
B 1 597 LEU 597 617 617 LEU LEU B . n 
B 1 598 CYS 598 618 618 CYS CYS B . n 
B 1 599 TYR 599 619 619 TYR TYR B . n 
B 1 600 ILE 600 620 620 ILE ILE B . n 
B 1 601 ILE 601 621 621 ILE ILE B . n 
B 1 602 LEU 602 622 622 LEU LEU B . n 
B 1 603 ALA 603 623 623 ALA ALA B . n 
B 1 604 GLY 604 624 624 GLY GLY B . n 
B 1 605 ILE 605 625 625 ILE ILE B . n 
B 1 606 CYS 606 626 626 CYS CYS B . n 
B 1 607 LEU 607 627 627 LEU LEU B . n 
B 1 608 GLY 608 628 628 GLY GLY B . n 
B 1 609 TYR 609 629 629 TYR TYR B . n 
B 1 610 LEU 610 630 630 LEU LEU B . n 
B 1 611 CYS 611 631 631 CYS CYS B . n 
B 1 612 THR 612 632 632 THR THR B . n 
B 1 613 PHE 613 633 633 PHE PHE B . n 
B 1 614 CYS 614 634 634 CYS CYS B . n 
B 1 615 LEU 615 635 635 LEU LEU B . n 
B 1 616 ILE 616 636 636 ILE ILE B . n 
B 1 617 ALA 617 637 637 ALA ALA B . n 
B 1 618 LYS 618 638 638 LYS LYS B . n 
B 1 619 PRO 619 639 639 PRO PRO B . n 
B 1 620 LYS 620 640 640 LYS LYS B . n 
B 1 621 GLN 621 641 641 GLN GLN B . n 
B 1 622 ILE 622 642 642 ILE ILE B . n 
B 1 623 TYR 623 643 643 TYR TYR B . n 
B 1 624 CYS 624 644 644 CYS CYS B . n 
B 1 625 TYR 625 645 645 TYR TYR B . n 
B 1 626 LEU 626 646 646 LEU LEU B . n 
B 1 627 GLN 627 647 647 GLN GLN B . n 
B 1 628 ARG 628 648 648 ARG ARG B . n 
B 1 629 ILE 629 649 649 ILE ILE B . n 
B 1 630 GLY 630 650 650 GLY GLY B . n 
B 1 631 ILE 631 651 651 ILE ILE B . n 
B 1 632 GLY 632 652 652 GLY GLY B . n 
B 1 633 LEU 633 653 653 LEU LEU B . n 
B 1 634 SER 634 654 654 SER SER B . n 
B 1 635 PRO 635 655 655 PRO PRO B . n 
B 1 636 ALA 636 656 656 ALA ALA B . n 
B 1 637 MET 637 657 657 MET MET B . n 
B 1 638 SER 638 658 658 SER SER B . n 
B 1 639 TYR 639 659 659 TYR TYR B . n 
B 1 640 SER 640 660 660 SER SER B . n 
B 1 641 ALA 641 661 661 ALA ALA B . n 
B 1 642 LEU 642 662 662 LEU LEU B . n 
B 1 643 VAL 643 663 663 VAL VAL B . n 
B 1 644 THR 644 664 664 THR THR B . n 
B 1 645 LYS 645 665 665 LYS LYS B . n 
B 1 646 THR 646 666 666 THR THR B . n 
B 1 647 ASN 647 667 667 ASN ASN B . n 
B 1 648 ARG 648 668 668 ARG ARG B . n 
B 1 649 ILE 649 669 669 ILE ILE B . n 
B 1 650 ALA 650 670 670 ALA ALA B . n 
B 1 651 ARG 651 671 671 ARG ARG B . n 
B 1 652 ILE 652 672 672 ILE ILE B . n 
B 1 653 LEU 653 673 673 LEU LEU B . n 
B 1 654 ALA 654 674 674 ALA ALA B . n 
B 1 655 GLY 655 675 675 GLY GLY B . n 
B 1 656 SER 656 676 ?   ?   ?   B . n 
B 1 657 LYS 657 677 ?   ?   ?   B . n 
B 1 658 LYS 658 678 ?   ?   ?   B . n 
B 1 659 LYS 659 679 ?   ?   ?   B . n 
B 1 660 ILE 660 680 ?   ?   ?   B . n 
B 1 661 CYS 661 681 ?   ?   ?   B . n 
B 1 662 THR 662 682 ?   ?   ?   B . n 
B 1 663 LYS 663 683 ?   ?   ?   B . n 
B 1 664 LYS 664 684 ?   ?   ?   B . n 
B 1 665 PRO 665 685 ?   ?   ?   B . n 
B 1 666 ARG 666 686 ?   ?   ?   B . n 
B 1 667 PHE 667 687 ?   ?   ?   B . n 
B 1 668 MET 668 688 688 MET MET B . n 
B 1 669 SER 669 689 689 SER SER B . n 
B 1 670 ALA 670 690 690 ALA ALA B . n 
B 1 671 CYS 671 691 691 CYS CYS B . n 
B 1 672 ALA 672 692 692 ALA ALA B . n 
B 1 673 GLN 673 693 693 GLN GLN B . n 
B 1 674 LEU 674 694 694 LEU LEU B . n 
B 1 675 VAL 675 695 695 VAL VAL B . n 
B 1 676 ILE 676 696 696 ILE ILE B . n 
B 1 677 ALA 677 697 697 ALA ALA B . n 
B 1 678 PHE 678 698 698 PHE PHE B . n 
B 1 679 ILE 679 699 699 ILE ILE B . n 
B 1 680 LEU 680 700 700 LEU LEU B . n 
B 1 681 ILE 681 701 701 ILE ILE B . n 
B 1 682 CYS 682 702 702 CYS CYS B . n 
B 1 683 ILE 683 703 703 ILE ILE B . n 
B 1 684 GLN 684 704 704 GLN GLN B . n 
B 1 685 LEU 685 705 705 LEU LEU B . n 
B 1 686 GLY 686 706 706 GLY GLY B . n 
B 1 687 ILE 687 707 707 ILE ILE B . n 
B 1 688 ILE 688 708 708 ILE ILE B . n 
B 1 689 VAL 689 709 709 VAL VAL B . n 
B 1 690 ALA 690 710 710 ALA ALA B . n 
B 1 691 LEU 691 711 711 LEU LEU B . n 
B 1 692 PHE 692 712 712 PHE PHE B . n 
B 1 693 ILE 693 713 713 ILE ILE B . n 
B 1 694 MET 694 714 714 MET MET B . n 
B 1 695 GLU 695 715 715 GLU GLU B . n 
B 1 696 PRO 696 716 716 PRO PRO B . n 
B 1 697 PRO 697 717 717 PRO PRO B . n 
B 1 698 ASP 698 718 718 ASP ASP B . n 
B 1 699 ILE 699 719 719 ILE ILE B . n 
B 1 700 MET 700 720 720 MET MET B . n 
B 1 701 HIS 701 721 721 HIS HIS B . n 
B 1 702 ASP 702 722 722 ASP ASP B . n 
B 1 703 TYR 703 723 723 TYR TYR B . n 
B 1 704 PRO 704 724 724 PRO PRO B . n 
B 1 705 SER 705 725 725 SER SER B . n 
B 1 706 ILE 706 726 726 ILE ILE B . n 
B 1 707 ARG 707 727 727 ARG ARG B . n 
B 1 708 GLU 708 728 728 GLU GLU B . n 
B 1 709 VAL 709 729 729 VAL VAL B . n 
B 1 710 TYR 710 730 730 TYR TYR B . n 
B 1 711 LEU 711 731 731 LEU LEU B . n 
B 1 712 ILE 712 732 732 ILE ILE B . n 
B 1 713 CYS 713 733 733 CYS CYS B . n 
B 1 714 ASN 714 734 734 ASN ASN B . n 
B 1 715 THR 715 735 735 THR THR B . n 
B 1 716 THR 716 736 736 THR THR B . n 
B 1 717 ASN 717 737 737 ASN ASN B . n 
B 1 718 LEU 718 738 738 LEU LEU B . n 
B 1 719 GLY 719 739 739 GLY GLY B . n 
B 1 720 VAL 720 740 740 VAL VAL B . n 
B 1 721 VAL 721 741 741 VAL VAL B . n 
B 1 722 ALA 722 742 742 ALA ALA B . n 
B 1 723 PRO 723 743 743 PRO PRO B . n 
B 1 724 LEU 724 744 744 LEU LEU B . n 
B 1 725 GLY 725 745 745 GLY GLY B . n 
B 1 726 TYR 726 746 746 TYR TYR B . n 
B 1 727 ASN 727 747 747 ASN ASN B . n 
B 1 728 GLY 728 748 748 GLY GLY B . n 
B 1 729 LEU 729 749 749 LEU LEU B . n 
B 1 730 LEU 730 750 750 LEU LEU B . n 
B 1 731 ILE 731 751 751 ILE ILE B . n 
B 1 732 LEU 732 752 752 LEU LEU B . n 
B 1 733 ALA 733 753 753 ALA ALA B . n 
B 1 734 CYS 734 754 754 CYS CYS B . n 
B 1 735 THR 735 755 755 THR THR B . n 
B 1 736 PHE 736 756 756 PHE PHE B . n 
B 1 737 TYR 737 757 757 TYR TYR B . n 
B 1 738 ALA 738 758 758 ALA ALA B . n 
B 1 739 PHE 739 759 759 PHE PHE B . n 
B 1 740 LYS 740 760 760 LYS LYS B . n 
B 1 741 THR 741 761 761 THR THR B . n 
B 1 742 ARG 742 762 762 ARG ARG B . n 
B 1 743 ASN 743 763 763 ASN ASN B . n 
B 1 744 VAL 744 764 764 VAL VAL B . n 
B 1 745 PRO 745 765 765 PRO PRO B . n 
B 1 746 ALA 746 766 766 ALA ALA B . n 
B 1 747 ASN 747 767 767 ASN ASN B . n 
B 1 748 PHE 748 768 768 PHE PHE B . n 
B 1 749 ASN 749 769 769 ASN ASN B . n 
B 1 750 GLU 750 770 770 GLU GLU B . n 
B 1 751 ALA 751 771 771 ALA ALA B . n 
B 1 752 LYS 752 772 772 LYS LYS B . n 
B 1 753 TYR 753 773 773 TYR TYR B . n 
B 1 754 ILE 754 774 774 ILE ILE B . n 
B 1 755 ALA 755 775 775 ALA ALA B . n 
B 1 756 PHE 756 776 776 PHE PHE B . n 
B 1 757 ALA 757 777 777 ALA ALA B . n 
B 1 758 MET 758 778 778 MET MET B . n 
B 1 759 TYR 759 779 779 TYR TYR B . n 
B 1 760 THR 760 780 780 THR THR B . n 
B 1 761 THR 761 781 781 THR THR B . n 
B 1 762 CYS 762 782 782 CYS CYS B . n 
B 1 763 ILE 763 783 783 ILE ILE B . n 
B 1 764 ILE 764 784 784 ILE ILE B . n 
B 1 765 TRP 765 785 785 TRP TRP B . n 
B 1 766 LEU 766 786 786 LEU LEU B . n 
B 1 767 ALA 767 787 787 ALA ALA B . n 
B 1 768 PHE 768 788 788 PHE PHE B . n 
B 1 769 VAL 769 789 789 VAL VAL B . n 
B 1 770 PRO 770 790 790 PRO PRO B . n 
B 1 771 ILE 771 791 791 ILE ILE B . n 
B 1 772 TYR 772 792 792 TYR TYR B . n 
B 1 773 PHE 773 793 793 PHE PHE B . n 
B 1 774 GLY 774 794 794 GLY GLY B . n 
B 1 775 SER 775 795 795 SER SER B . n 
B 1 776 ASN 776 796 796 ASN ASN B . n 
B 1 777 TYR 777 797 797 TYR TYR B . n 
B 1 778 LYS 778 798 798 LYS LYS B . n 
B 1 779 ALA 779 799 799 ALA ALA B . n 
B 1 780 ILE 780 800 800 ILE ILE B . n 
B 1 781 THR 781 801 801 THR THR B . n 
B 1 782 MET 782 802 802 MET MET B . n 
B 1 783 CYS 783 803 803 CYS CYS B . n 
B 1 784 PHE 784 804 804 PHE PHE B . n 
B 1 785 SER 785 805 805 SER SER B . n 
B 1 786 VAL 786 806 806 VAL VAL B . n 
B 1 787 SER 787 807 807 SER SER B . n 
B 1 788 LEU 788 808 808 LEU LEU B . n 
B 1 789 SER 789 809 809 SER SER B . n 
B 1 790 ALA 790 810 810 ALA ALA B . n 
B 1 791 THR 791 811 811 THR THR B . n 
B 1 792 VAL 792 812 812 VAL VAL B . n 
B 1 793 LEU 793 813 813 LEU LEU B . n 
B 1 794 LEU 794 814 814 LEU LEU B . n 
B 1 795 GLY 795 815 815 GLY GLY B . n 
B 1 796 CYS 796 816 816 CYS CYS B . n 
B 1 797 MET 797 817 817 MET MET B . n 
B 1 798 PHE 798 818 818 PHE PHE B . n 
B 1 799 VAL 799 819 819 VAL VAL B . n 
B 1 800 PRO 800 820 820 PRO PRO B . n 
B 1 801 LYS 801 821 821 LYS LYS B . n 
B 1 802 VAL 802 822 822 VAL VAL B . n 
B 1 803 TYR 803 823 823 TYR TYR B . n 
B 1 804 ILE 804 824 824 ILE ILE B . n 
B 1 805 ILE 805 825 825 ILE ILE B . n 
B 1 806 LEU 806 826 826 LEU LEU B . n 
B 1 807 ALA 807 827 827 ALA ALA B . n 
B 1 808 LYS 808 828 ?   ?   ?   B . n 
B 1 809 PRO 809 829 ?   ?   ?   B . n 
B 1 810 GLU 810 830 ?   ?   ?   B . n 
B 1 811 ARG 811 831 ?   ?   ?   B . n 
B 1 812 ASN 812 832 ?   ?   ?   B . n 
B 1 813 VAL 813 833 ?   ?   ?   B . n 
B 1 814 ARG 814 834 ?   ?   ?   B . n 
B 1 815 SER 815 835 ?   ?   ?   B . n 
B 1 816 ALA 816 836 ?   ?   ?   B . n 
B 1 817 PHE 817 837 ?   ?   ?   B . n 
B 1 818 THR 818 838 ?   ?   ?   B . n 
B 1 819 THR 819 839 ?   ?   ?   B . n 
B 1 820 SER 820 840 ?   ?   ?   B . n 
B 1 821 THR 821 841 ?   ?   ?   B . n 
B 1 822 VAL 822 842 ?   ?   ?   B . n 
B 1 823 VAL 823 843 ?   ?   ?   B . n 
B 1 824 ARG 824 844 ?   ?   ?   B . n 
B 1 825 MET 825 845 ?   ?   ?   B . n 
B 1 826 HIS 826 846 ?   ?   ?   B . n 
B 1 827 VAL 827 847 ?   ?   ?   B . n 
B 1 828 GLY 828 848 ?   ?   ?   B . n 
B 1 829 ASP 829 849 ?   ?   ?   B . n 
B 1 830 GLY 830 850 ?   ?   ?   B . n 
B 1 831 LYS 831 851 ?   ?   ?   B . n 
B 1 832 SER 832 852 ?   ?   ?   B . n 
B 1 833 SER 833 853 ?   ?   ?   B . n 
B 1 834 SER 834 854 ?   ?   ?   B . n 
B 1 835 ALA 835 855 ?   ?   ?   B . n 
B 1 836 ALA 836 856 ?   ?   ?   B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 QUS ? ? QUS ? ? 'SUBJECT OF INVESTIGATION' ? 
2 XQT ? ? XQT ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 NAG 1 901 901 NAG NAG A . 
D 3 QUS 1 902 902 QUS QUS A . 
E 4 XQT 1 903 903 XQT XQT A . 
F 2 NAG 1 901 901 NAG NAG B . 
G 3 QUS 1 902 902 QUS QUS B . 
H 4 XQT 1 903 903 XQT XQT B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8X0D 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8X0D 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8X0D 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               97.269 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.901 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  'HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8X0D 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.50 
_refine.ls_d_res_low                             184.07 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     82470 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    100.00 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.32671 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.32671 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'PARAMETERS FOR MASK CACLULATION' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD WITH PHASES' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.687 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             31.609 
_refine.overall_SU_ML                            0.484 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       . 
_refine_hist.d_res_low                        . 
_refine_hist.number_atoms_solvent             ? 
_refine_hist.number_atoms_total               12176 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        ? 
_refine_hist.pdbx_number_atoms_nucleic_acid   ? 
_refine_hist.pdbx_number_atoms_ligand         ? 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003  0.012  12475 ? r_bond_refined_d             ? ? 
'ELECTRON MICROSCOPY' ? 0.000  0.016  11828 ? r_bond_other_d               ? ? 
'ELECTRON MICROSCOPY' ? 0.909  1.640  16924 ? r_angle_refined_deg          ? ? 
'ELECTRON MICROSCOPY' ? 0.357  1.564  27238 ? r_angle_other_deg            ? ? 
'ELECTRON MICROSCOPY' ? 5.465  5.000  1530  ? r_dihedral_angle_1_deg       ? ? 
'ELECTRON MICROSCOPY' ? 4.012  5.286  70    ? r_dihedral_angle_2_deg       ? ? 
'ELECTRON MICROSCOPY' ? 16.522 10.000 2126  ? r_dihedral_angle_3_deg       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'ELECTRON MICROSCOPY' ? 0.050  0.200  1894  ? r_chiral_restr               ? ? 
'ELECTRON MICROSCOPY' ? 0.004  0.020  14306 ? r_gen_planes_refined         ? ? 
'ELECTRON MICROSCOPY' ? 0.001  0.020  2866  ? r_gen_planes_other           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'ELECTRON MICROSCOPY' ? 3.335  9.616  6138  ? r_mcbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 3.335  9.616  6138  ? r_mcbond_other               ? ? 
'ELECTRON MICROSCOPY' ? 6.105  17.263 7662  ? r_mcangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 6.105  17.266 7663  ? r_mcangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 2.741  9.936  6337  ? r_scbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 2.741  9.936  6338  ? r_scbond_other               ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 5.303  18.286 9263  ? r_scangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 16.044 110.45 51411 ? r_long_range_B_refined       ? ? 
'ELECTRON MICROSCOPY' ? 16.044 110.45 51412 ? r_long_range_B_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_ls_shell.d_res_high                       3.500 
_refine_ls_shell.d_res_low                        3.591 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             0 
_refine_ls_shell.number_reflns_R_work             6140 
_refine_ls_shell.percent_reflns_obs               100.00 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.773 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.000 
# 
_struct.entry_id                     8X0D 
_struct.title                        
'Human FL Metabotropic glutamate receptor 5, mGlu5-5M with quisqualate and VU0424465, conformer 2' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8X0D 
_struct_keywords.text            
'G-PROTEIN COUPLED RECEPTORS, SIGNAL TRANSDUCTION, METABOTROPIC GLUTAMATE RECEPTOR, Agonist, active state, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
F N N 2 ? 
G N N 3 ? 
H N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    GRM5_HUMAN 
_struct_ref.pdbx_db_accession          P41594 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;QSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCW
HSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLS
DKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKL
LKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDY
YLKLRPETNHRNPWFQEFWQHRFQCRLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP
GYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDDDEVW
SKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEP
IAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYS
ALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVYLICNTTNLGV
VTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVP
KVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAA
;
_struct_ref.pdbx_align_begin           21 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8X0D A 1 ? 836 ? P41594 21 ? 856 ? 21 856 
2 1 8X0D B 1 ? 836 ? P41594 21 ? 856 ? 21 856 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8X0D LEU A 330 ? UNP P41594 HIS 350 'engineered mutation' 350 1  
1 8X0D ALA A 425 ? UNP P41594 ASN 445 'engineered mutation' 445 2  
1 8X0D ALA A 722 ? UNP P41594 THR 742 'engineered mutation' 742 3  
1 8X0D ALA A 733 ? UNP P41594 SER 753 'engineered mutation' 753 4  
1 8X0D ALA A 757 ? UNP P41594 THR 777 'engineered mutation' 777 5  
1 8X0D ALA A 779 ? UNP P41594 ILE 799 'engineered mutation' 799 6  
1 8X0D LEU A 793 ? UNP P41594 ALA 813 'engineered mutation' 813 7  
2 8X0D LEU B 330 ? UNP P41594 HIS 350 'engineered mutation' 350 8  
2 8X0D ALA B 425 ? UNP P41594 ASN 445 'engineered mutation' 445 9  
2 8X0D ALA B 722 ? UNP P41594 THR 742 'engineered mutation' 742 10 
2 8X0D ALA B 733 ? UNP P41594 SER 753 'engineered mutation' 753 11 
2 8X0D ALA B 757 ? UNP P41594 THR 777 'engineered mutation' 777 12 
2 8X0D ALA B 779 ? UNP P41594 ILE 799 'engineered mutation' 799 13 
2 8X0D LEU B 793 ? UNP P41594 ALA 813 'engineered mutation' 813 14 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 45  ? ASP A 62  ? GLY A 65  ASP A 82  1 ? 18 
HELX_P HELX_P2  AA2 HIS A 81  ? ARG A 94  ? HIS A 101 ARG A 114 1 ? 14 
HELX_P HELX_P3  AA3 SER A 131 ? GLN A 143 ? SER A 151 GLN A 163 1 ? 13 
HELX_P HELX_P4  AA4 LEU A 144 ? ASN A 146 ? LEU A 164 ASN A 166 5 ? 3  
HELX_P HELX_P5  AA5 SER A 156 ? ASP A 161 ? SER A 176 ASP A 181 5 ? 6  
HELX_P HELX_P6  AA6 SER A 174 ? TYR A 189 ? SER A 194 TYR A 209 1 ? 16 
HELX_P HELX_P7  AA7 ASN A 202 ? GLU A 218 ? ASN A 222 GLU A 238 1 ? 17 
HELX_P HELX_P8  AA8 GLY A 233 ? SER A 246 ? GLY A 253 SER A 266 1 ? 14 
HELX_P HELX_P9  AA9 GLU A 259 ? LEU A 273 ? GLU A 279 LEU A 293 1 ? 15 
HELX_P HELX_P10 AB1 TYR A 297 ? ALA A 301 ? TYR A 317 ALA A 321 5 ? 5  
HELX_P HELX_P11 AB2 VAL A 314 ? LEU A 322 ? VAL A 334 LEU A 342 1 ? 9  
HELX_P HELX_P12 AB3 TRP A 334 ? PHE A 343 ? TRP A 354 PHE A 363 1 ? 10 
HELX_P HELX_P13 AB4 LYS A 376 ? CYS A 399 ? LYS A 396 CYS A 419 1 ? 24 
HELX_P HELX_P14 AB5 CYS A 406 ? LYS A 410 ? CYS A 426 LYS A 430 5 ? 5  
HELX_P HELX_P15 AB6 ASP A 413 ? THR A 424 ? ASP A 433 THR A 444 1 ? 12 
HELX_P HELX_P16 AB7 ASP A 557 ? TYR A 584 ? ASP A 577 TYR A 604 1 ? 28 
HELX_P HELX_P17 AB8 THR A 587 ? LYS A 591 ? THR A 607 LYS A 611 5 ? 5  
HELX_P HELX_P18 AB9 SER A 594 ? ILE A 616 ? SER A 614 ILE A 636 1 ? 23 
HELX_P HELX_P19 AC1 LYS A 620 ? GLY A 655 ? LYS A 640 GLY A 675 1 ? 36 
HELX_P HELX_P20 AC2 ALA A 670 ? GLU A 695 ? ALA A 690 GLU A 715 1 ? 26 
HELX_P HELX_P21 AC3 THR A 716 ? ARG A 742 ? THR A 736 ARG A 762 1 ? 27 
HELX_P HELX_P22 AC4 ASN A 749 ? PHE A 768 ? ASN A 769 PHE A 788 1 ? 20 
HELX_P HELX_P23 AC5 PHE A 768 ? GLY A 774 ? PHE A 788 GLY A 794 1 ? 7  
HELX_P HELX_P24 AC6 TYR A 777 ? MET A 797 ? TYR A 797 MET A 817 1 ? 21 
HELX_P HELX_P25 AC7 PHE A 798 ? ALA A 807 ? PHE A 818 ALA A 827 1 ? 10 
HELX_P HELX_P26 AC8 GLY B 45  ? ASP B 62  ? GLY B 65  ASP B 82  1 ? 18 
HELX_P HELX_P27 AC9 HIS B 81  ? ARG B 94  ? HIS B 101 ARG B 114 1 ? 14 
HELX_P HELX_P28 AD1 SER B 131 ? GLN B 143 ? SER B 151 GLN B 163 1 ? 13 
HELX_P HELX_P29 AD2 LEU B 144 ? ASN B 146 ? LEU B 164 ASN B 166 5 ? 3  
HELX_P HELX_P30 AD3 SER B 156 ? ASP B 161 ? SER B 176 ASP B 181 5 ? 6  
HELX_P HELX_P31 AD4 SER B 174 ? TYR B 189 ? SER B 194 TYR B 209 1 ? 16 
HELX_P HELX_P32 AD5 ASN B 202 ? GLY B 219 ? ASN B 222 GLY B 239 1 ? 18 
HELX_P HELX_P33 AD6 GLY B 233 ? SER B 246 ? GLY B 253 SER B 266 1 ? 14 
HELX_P HELX_P34 AD7 GLU B 259 ? LEU B 273 ? GLU B 279 LEU B 293 1 ? 15 
HELX_P HELX_P35 AD8 TYR B 297 ? ALA B 301 ? TYR B 317 ALA B 321 5 ? 5  
HELX_P HELX_P36 AD9 VAL B 314 ? LEU B 322 ? VAL B 334 LEU B 342 1 ? 9  
HELX_P HELX_P37 AE1 TRP B 334 ? PHE B 343 ? TRP B 354 PHE B 363 1 ? 10 
HELX_P HELX_P38 AE2 LYS B 376 ? CYS B 399 ? LYS B 396 CYS B 419 1 ? 24 
HELX_P HELX_P39 AE3 CYS B 406 ? LYS B 410 ? CYS B 426 LYS B 430 5 ? 5  
HELX_P HELX_P40 AE4 ASP B 413 ? THR B 424 ? ASP B 433 THR B 444 1 ? 12 
HELX_P HELX_P41 AE5 ASP B 540 ? THR B 543 ? ASP B 560 THR B 563 5 ? 4  
HELX_P HELX_P42 AE6 ASP B 557 ? TYR B 584 ? ASP B 577 TYR B 604 1 ? 28 
HELX_P HELX_P43 AE7 GLU B 596 ? ILE B 616 ? GLU B 616 ILE B 636 1 ? 21 
HELX_P HELX_P44 AE8 LYS B 620 ? GLY B 655 ? LYS B 640 GLY B 675 1 ? 36 
HELX_P HELX_P45 AE9 CYS B 671 ? GLU B 695 ? CYS B 691 GLU B 715 1 ? 25 
HELX_P HELX_P46 AF1 THR B 716 ? THR B 741 ? THR B 736 THR B 761 1 ? 26 
HELX_P HELX_P47 AF2 ASN B 749 ? PHE B 768 ? ASN B 769 PHE B 788 1 ? 20 
HELX_P HELX_P48 AF3 PHE B 768 ? PHE B 773 ? PHE B 788 PHE B 793 1 ? 6  
HELX_P HELX_P49 AF4 TYR B 777 ? MET B 797 ? TYR B 797 MET B 817 1 ? 21 
HELX_P HELX_P50 AF5 PHE B 798 ? ALA B 807 ? PHE B 818 ALA B 827 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?   ? A CYS 37  SG  ? ? ? 1_555 A CYS 79  SG ? ? A CYS 57  A CYS 99  1_555 ? ? ? ? ? ? ? 2.053 ? ?               
disulf2  disulf ?   ? A CYS 221 SG  ? ? ? 1_555 A CYS 510 SG ? ? A CYS 241 A CYS 530 1_555 ? ? ? ? ? ? ? 2.039 ? ?               
disulf3  disulf ?   ? A CYS 256 SG  ? ? ? 1_555 A CYS 258 SG ? ? A CYS 276 A CYS 278 1_555 ? ? ? ? ? ? ? 2.038 ? ?               
disulf4  disulf ?   ? A CYS 345 SG  ? ? ? 1_555 A CYS 361 SG ? ? A CYS 365 A CYS 381 1_555 ? ? ? ? ? ? ? 2.044 ? ?               
disulf5  disulf ?   ? A CYS 399 SG  ? ? ? 1_555 A CYS 406 SG ? ? A CYS 419 A CYS 426 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf6  disulf ?   ? A CYS 491 SG  ? ? ? 1_555 A CYS 511 SG ? ? A CYS 511 A CYS 531 1_555 ? ? ? ? ? ? ? 2.042 ? ?               
disulf7  disulf ?   ? A CYS 495 SG  ? ? ? 1_555 A CYS 514 SG ? ? A CYS 515 A CYS 534 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf8  disulf ?   ? A CYS 517 SG  ? ? ? 1_555 A CYS 529 SG ? ? A CYS 537 A CYS 549 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf9  disulf ?   ? A CYS 532 SG  ? ? ? 1_555 A CYS 545 SG ? ? A CYS 552 A CYS 565 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf10 disulf ?   ? A CYS 624 SG  ? ? ? 1_555 A CYS 713 SG ? ? A CYS 644 A CYS 733 1_555 ? ? ? ? ? ? ? 2.017 ? ?               
disulf11 disulf ?   ? B CYS 37  SG  ? ? ? 1_555 B CYS 79  SG ? ? B CYS 57  B CYS 99  1_555 ? ? ? ? ? ? ? 2.054 ? ?               
disulf12 disulf ?   ? B CYS 221 SG  ? ? ? 1_555 B CYS 510 SG ? ? B CYS 241 B CYS 530 1_555 ? ? ? ? ? ? ? 2.023 ? ?               
disulf13 disulf ?   ? B CYS 256 SG  ? ? ? 1_555 B CYS 258 SG ? ? B CYS 276 B CYS 278 1_555 ? ? ? ? ? ? ? 2.047 ? ?               
disulf14 disulf ?   ? B CYS 345 SG  ? ? ? 1_555 B CYS 361 SG ? ? B CYS 365 B CYS 381 1_555 ? ? ? ? ? ? ? 2.038 ? ?               
disulf15 disulf ?   ? B CYS 399 SG  ? ? ? 1_555 B CYS 406 SG ? ? B CYS 419 B CYS 426 1_555 ? ? ? ? ? ? ? 2.027 ? ?               
disulf16 disulf ?   ? B CYS 491 SG  ? ? ? 1_555 B CYS 511 SG ? ? B CYS 511 B CYS 531 1_555 ? ? ? ? ? ? ? 2.025 ? ?               
disulf17 disulf ?   ? B CYS 495 SG  ? ? ? 1_555 B CYS 514 SG ? ? B CYS 515 B CYS 534 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf18 disulf ?   ? B CYS 517 SG  ? ? ? 1_555 B CYS 529 SG ? ? B CYS 537 B CYS 549 1_555 ? ? ? ? ? ? ? 2.044 ? ?               
disulf19 disulf ?   ? B CYS 532 SG  ? ? ? 1_555 B CYS 545 SG ? ? B CYS 552 B CYS 565 1_555 ? ? ? ? ? ? ? 2.038 ? ?               
disulf20 disulf ?   ? B CYS 624 SG  ? ? ? 1_555 B CYS 713 SG ? ? B CYS 644 B CYS 733 1_555 ? ? ? ? ? ? ? 2.047 ? ?               
covale1  covale one ? A ASN 190 ND2 ? ? ? 1_555 C NAG .   C1 ? ? A ASN 210 A NAG 901 1_555 ? ? ? ? ? ? ? 1.451 ? N-Glycosylation 
covale2  covale one ? B ASN 190 ND2 ? ? ? 1_555 F NAG .   C1 ? ? B ASN 210 B NAG 901 1_555 ? ? ? ? ? ? ? 1.461 ? N-Glycosylation 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG C .   ? ASN A 190 ? NAG A 901 ? 1_555 ASN A 210 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG F .   ? ASN B 190 ? NAG B 901 ? 1_555 ASN B 210 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  CYS A 37  ? CYS A 79  ? CYS A 57  ? 1_555 CYS A 99  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
4  CYS A 221 ? CYS A 510 ? CYS A 241 ? 1_555 CYS A 530 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
5  CYS A 256 ? CYS A 258 ? CYS A 276 ? 1_555 CYS A 278 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6  CYS A 345 ? CYS A 361 ? CYS A 365 ? 1_555 CYS A 381 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7  CYS A 399 ? CYS A 406 ? CYS A 419 ? 1_555 CYS A 426 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
8  CYS A 491 ? CYS A 511 ? CYS A 511 ? 1_555 CYS A 531 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
9  CYS A 495 ? CYS A 514 ? CYS A 515 ? 1_555 CYS A 534 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
10 CYS A 517 ? CYS A 529 ? CYS A 537 ? 1_555 CYS A 549 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
11 CYS A 532 ? CYS A 545 ? CYS A 552 ? 1_555 CYS A 565 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
12 CYS A 624 ? CYS A 713 ? CYS A 644 ? 1_555 CYS A 733 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
13 CYS B 37  ? CYS B 79  ? CYS B 57  ? 1_555 CYS B 99  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
14 CYS B 221 ? CYS B 510 ? CYS B 241 ? 1_555 CYS B 530 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
15 CYS B 256 ? CYS B 258 ? CYS B 276 ? 1_555 CYS B 278 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
16 CYS B 345 ? CYS B 361 ? CYS B 365 ? 1_555 CYS B 381 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
17 CYS B 399 ? CYS B 406 ? CYS B 419 ? 1_555 CYS B 426 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
18 CYS B 491 ? CYS B 511 ? CYS B 511 ? 1_555 CYS B 531 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
19 CYS B 495 ? CYS B 514 ? CYS B 515 ? 1_555 CYS B 534 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
20 CYS B 517 ? CYS B 529 ? CYS B 537 ? 1_555 CYS B 549 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
21 CYS B 532 ? CYS B 545 ? CYS B 552 ? 1_555 CYS B 565 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
22 CYS B 624 ? CYS B 713 ? CYS B 644 ? 1_555 CYS B 733 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
AA7 ? 2 ? 
AA8 ? 2 ? 
AA9 ? 6 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 2 ? 
AB4 ? 2 ? 
AB5 ? 2 ? 
AB6 ? 2 ? 
AB7 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA2 1 2 ? parallel      
AA2 2 3 ? parallel      
AA2 3 4 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? parallel      
AA9 3 4 ? parallel      
AA9 4 5 ? parallel      
AA9 5 6 ? parallel      
AB1 1 2 ? parallel      
AB1 2 3 ? parallel      
AB1 3 4 ? parallel      
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB7 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 71  ? ASP A 77  ? LEU A 91  ASP A 97  
AA1 2 ILE A 15  ? PHE A 21  ? ILE A 35  PHE A 41  
AA1 3 ILE A 123 ? ILE A 127 ? ILE A 143 ILE A 147 
AA1 4 GLN A 149 ? ALA A 151 ? GLN A 169 ALA A 171 
AA1 5 PHE A 168 ? ARG A 170 ? PHE A 188 ARG A 190 
AA2 1 CYS A 221 ? ILE A 228 ? CYS A 241 ILE A 248 
AA2 2 TYR A 193 ? THR A 199 ? TYR A 213 THR A 219 
AA2 3 VAL A 253 ? PHE A 257 ? VAL A 273 PHE A 277 
AA2 4 LEU A 280 ? LEU A 282 ? LEU A 300 LEU A 302 
AA3 1 ILE A 305 ? LEU A 309 ? ILE A 325 LEU A 329 
AA3 2 TYR A 446 ? GLY A 455 ? TYR A 466 GLY A 475 
AA3 3 TYR A 458 ? ASP A 468 ? TYR A 478 ASP A 488 
AA3 4 GLU A 471 ? MET A 474 ? GLU A 491 MET A 494 
AA4 1 ALA A 425 ? THR A 427 ? ALA A 445 THR A 447 
AA4 2 THR A 433 ? LEU A 435 ? THR A 453 LEU A 455 
AA5 1 ILE A 500 ? VAL A 508 ? ILE A 520 VAL A 528 
AA5 2 CYS A 511 ? PRO A 516 ? CYS A 531 PRO A 536 
AA6 1 GLU A 521 ? ASP A 525 ? GLU A 541 ASP A 545 
AA6 2 THR A 528 ? ALA A 531 ? THR A 548 ALA A 551 
AA7 1 SER A 536 ? PRO A 538 ? SER A 556 PRO A 558 
AA7 2 CYS A 545 ? LEU A 547 ? CYS A 565 LEU A 567 
AA8 1 ILE A 699 ? ASP A 702 ? ILE A 719 ASP A 722 
AA8 2 TYR A 710 ? CYS A 713 ? TYR A 730 CYS A 733 
AA9 1 ALA B 9   ? MET B 11  ? ALA B 29  MET B 31  
AA9 2 LEU B 71  ? ASP B 77  ? LEU B 91  ASP B 97  
AA9 3 ILE B 15  ? PHE B 21  ? ILE B 35  PHE B 41  
AA9 4 ILE B 123 ? ILE B 127 ? ILE B 143 ILE B 147 
AA9 5 GLN B 149 ? ALA B 151 ? GLN B 169 ALA B 171 
AA9 6 PHE B 168 ? ARG B 170 ? PHE B 188 ARG B 190 
AB1 1 CYS B 221 ? ILE B 228 ? CYS B 241 ILE B 248 
AB1 2 TYR B 193 ? THR B 199 ? TYR B 213 THR B 219 
AB1 3 VAL B 253 ? PHE B 257 ? VAL B 273 PHE B 277 
AB1 4 LEU B 280 ? LEU B 282 ? LEU B 300 LEU B 302 
AB2 1 ILE B 305 ? LEU B 309 ? ILE B 325 LEU B 329 
AB2 2 TYR B 446 ? GLY B 455 ? TYR B 466 GLY B 475 
AB2 3 TYR B 458 ? ASP B 468 ? TYR B 478 ASP B 488 
AB2 4 GLU B 471 ? MET B 474 ? GLU B 491 MET B 494 
AB3 1 ALA B 425 ? THR B 427 ? ALA B 445 THR B 447 
AB3 2 THR B 433 ? LEU B 435 ? THR B 453 LEU B 455 
AB4 1 ILE B 500 ? ILE B 503 ? ILE B 520 ILE B 523 
AB4 2 THR B 513 ? PRO B 516 ? THR B 533 PRO B 536 
AB5 1 GLU B 521 ? ASP B 525 ? GLU B 541 ASP B 545 
AB5 2 THR B 528 ? ALA B 531 ? THR B 548 ALA B 551 
AB6 1 SER B 536 ? PRO B 538 ? SER B 556 PRO B 558 
AB6 2 CYS B 545 ? LEU B 547 ? CYS B 565 LEU B 567 
AB7 1 ILE B 699 ? ASP B 702 ? ILE B 719 ASP B 722 
AB7 2 TYR B 710 ? CYS B 713 ? TYR B 730 CYS B 733 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O GLY A 72  ? O GLY A 92  N ILE A 17  ? N ILE A 37  
AA1 2 3 N GLY A 18  ? N GLY A 38  O GLY A 125 ? O GLY A 145 
AA1 3 4 N VAL A 126 ? N VAL A 146 O ILE A 150 ? O ILE A 170 
AA1 4 5 N ALA A 151 ? N ALA A 171 O MET A 169 ? O MET A 189 
AA2 1 2 O ALA A 223 ? O ALA A 243 N VAL A 194 ? N VAL A 214 
AA2 2 3 N VAL A 197 ? N VAL A 217 O ALA A 255 ? O ALA A 275 
AA2 3 4 N CYS A 256 ? N CYS A 276 O LEU A 282 ? O LEU A 302 
AA3 1 2 N LYS A 308 ? N LYS A 328 O GLU A 447 ? O GLU A 467 
AA3 2 3 N ASN A 450 ? N ASN A 470 O ILE A 462 ? O ILE A 482 
AA3 3 4 N SER A 466 ? N SER A 486 O LYS A 473 ? O LYS A 493 
AA4 1 2 N PHE A 426 ? N PHE A 446 O ILE A 434 ? O ILE A 454 
AA5 1 2 N LYS A 501 ? N LYS A 521 O THR A 515 ? O THR A 535 
AA6 1 2 N TYR A 522 ? N TYR A 542 O LYS A 530 ? O LYS A 550 
AA7 1 2 N TRP A 537 ? N TRP A 557 O ASP A 546 ? O ASP A 566 
AA8 1 2 N MET A 700 ? N MET A 720 O ILE A 712 ? O ILE A 732 
AA9 1 2 N ALA B 9   ? N ALA B 29  O ILE B 75  ? O ILE B 95  
AA9 2 3 O ARG B 76  ? O ARG B 96  N ALA B 19  ? N ALA B 39  
AA9 3 4 N GLY B 18  ? N GLY B 38  O GLY B 125 ? O GLY B 145 
AA9 4 5 N VAL B 126 ? N VAL B 146 O ILE B 150 ? O ILE B 170 
AA9 5 6 N ALA B 151 ? N ALA B 171 O MET B 169 ? O MET B 189 
AB1 1 2 O ALA B 223 ? O ALA B 243 N VAL B 194 ? N VAL B 214 
AB1 2 3 N VAL B 197 ? N VAL B 217 O ALA B 255 ? O ALA B 275 
AB1 3 4 N CYS B 256 ? N CYS B 276 O LEU B 282 ? O LEU B 302 
AB2 1 2 N LYS B 308 ? N LYS B 328 O GLU B 447 ? O GLU B 467 
AB2 2 3 N TYR B 446 ? N TYR B 466 O TRP B 467 ? O TRP B 487 
AB2 3 4 N SER B 466 ? N SER B 486 O LYS B 473 ? O LYS B 493 
AB3 1 2 N PHE B 426 ? N PHE B 446 O ILE B 434 ? O ILE B 454 
AB4 1 2 N LYS B 501 ? N LYS B 521 O THR B 515 ? O THR B 535 
AB5 1 2 N ASP B 525 ? N ASP B 545 O THR B 528 ? O THR B 548 
AB6 1 2 N TRP B 537 ? N TRP B 557 O ASP B 546 ? O ASP B 566 
AB7 1 2 N MET B 700 ? N MET B 720 O ILE B 712 ? O ILE B 732 
# 
_pdbx_entry_details.entry_id                   8X0D 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TYR A 187 ? ? -90.90  51.63   
2  1 PHE A 277 ? ? -92.52  58.09   
3  1 ALA A 308 ? ? 52.83   -121.72 
4  1 GLN A 364 ? ? -57.48  105.19  
5  1 ASN A 374 ? ? 61.65   68.69   
6  1 SER A 384 ? ? -140.02 13.35   
7  1 ASP A 457 ? ? -79.55  -167.25 
8  1 TRP A 500 ? ? 57.23   70.03   
9  1 LYS A 502 ? ? 177.77  165.10  
10 1 ASN A 505 ? ? -78.52  -168.69 
11 1 THR A 533 ? ? -110.47 -168.02 
12 1 TYR A 547 ? ? 71.10   -9.24   
13 1 GLN A 553 ? ? -68.18  -76.30  
14 1 LEU A 554 ? ? -150.97 -39.84  
15 1 TYR A 572 ? ? -149.06 -159.60 
16 1 ARG A 574 ? ? 60.70   85.32   
17 1 ASP A 577 ? ? 72.21   151.76  
18 1 LYS A 611 ? ? -126.17 -54.38  
19 1 SER A 689 ? ? 89.97   -168.87 
20 1 ALA A 690 ? ? 50.73   -100.88 
21 1 ARG A 762 ? ? 59.89   -110.63 
22 1 ALA A 766 ? ? -145.58 -159.62 
23 1 ASN A 767 ? ? -68.11  78.56   
24 1 CYS A 816 ? ? -66.53  7.59    
25 1 PHE A 818 ? ? 67.05   -50.75  
26 1 ASN B 88  ? ? 75.79   -0.18   
27 1 TYR B 187 ? ? -90.76  52.83   
28 1 PHE B 277 ? ? -93.34  54.21   
29 1 ALA B 308 ? ? 53.36   -126.90 
30 1 GLN B 364 ? ? -57.52  105.32  
31 1 SER B 383 ? ? -82.88  49.54   
32 1 SER B 384 ? ? -140.71 15.48   
33 1 ASP B 457 ? ? -77.92  -169.77 
34 1 MET B 474 ? ? -97.58  -60.32  
35 1 LYS B 502 ? ? 176.97  167.92  
36 1 CYS B 515 ? ? -101.57 42.44   
37 1 LYS B 525 ? ? -158.62 49.63   
38 1 GLU B 527 ? ? -110.79 -168.92 
39 1 SER B 529 ? ? -65.94  50.65   
40 1 CYS B 530 ? ? -142.16 -29.41  
41 1 ASP B 577 ? ? 70.74   147.26  
42 1 THR B 607 ? ? -28.97  130.41  
43 1 SER B 689 ? ? 26.55   -120.47 
44 1 ALA B 690 ? ? 60.48   -113.69 
45 1 ASN B 767 ? ? -69.03  95.50   
46 1 SER B 795 ? ? -79.77  21.51   
47 1 ASN B 796 ? ? 55.37   -129.12 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8X0D 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   95.3 
_em_3d_fitting.ref_space         RECIPROCAL 
_em_3d_fitting.ref_protocol      OTHER 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       'The model which is being curated was used as initial template' 
_em_3d_fitting_list.chain_id                      A 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   Other 
_em_3d_fitting_list.type                          other 
_em_3d_fitting_list.accession_code                D_1300042377 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    8X0D 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   'BACK PROJECTION' 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.5 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               41886 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          1 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Human FL Metabotropic glutamate receptor 5, mGlu5-5M' 
_em_entity_assembly.details              'Receptor purified in detergent micelles with agonist quisqualate and PAM' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_image_scans.entry_id                8X0D 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           14 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        4096 
_em_image_scans.dimension_width         4096 
_em_image_scans.frames_per_image        ? 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        8X0D 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         
'Images were collected with Aberration-free image shift and Fringe-free imaging with a Selectris energy filter in EFTEM mode' 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             1200 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           165000 
_em_imaging.calibrated_magnification        192572 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            50 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R0.6/1' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8X0D 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   283 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               'Blotting time of 5 seconds and blot force of 10' 
# 
_em_experiment.entry_id                8X0D 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              8X0D 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A GLN 21  ? A GLN 1   
2   1 Y 1 A SER 22  ? A SER 2   
3   1 Y 1 A SER 23  ? A SER 3   
4   1 Y 1 A GLU 24  ? A GLU 4   
5   1 Y 1 A ILE 118 ? A ILE 98  
6   1 Y 1 A SER 119 ? A SER 99  
7   1 Y 1 A SER 120 ? A SER 100 
8   1 Y 1 A GLU 121 ? A GLU 101 
9   1 Y 1 A GLU 122 ? A GLU 102 
10  1 Y 1 A GLU 123 ? A GLU 103 
11  1 Y 1 A GLU 124 ? A GLU 104 
12  1 Y 1 A GLY 125 ? A GLY 105 
13  1 Y 1 A LEU 126 ? A LEU 106 
14  1 Y 1 A VAL 127 ? A VAL 107 
15  1 Y 1 A ARG 128 ? A ARG 108 
16  1 Y 1 A CYS 129 ? A CYS 109 
17  1 Y 1 A VAL 130 ? A VAL 110 
18  1 Y 1 A ASP 131 ? A ASP 111 
19  1 Y 1 A GLY 132 ? A GLY 112 
20  1 Y 1 A SER 133 ? A SER 113 
21  1 Y 1 A SER 134 ? A SER 114 
22  1 Y 1 A SER 135 ? A SER 115 
23  1 Y 1 A SER 136 ? A SER 116 
24  1 Y 1 A PHE 137 ? A PHE 117 
25  1 Y 1 A ARG 138 ? A ARG 118 
26  1 Y 1 A SER 139 ? A SER 119 
27  1 Y 1 A LYS 140 ? A LYS 120 
28  1 Y 1 A SER 676 ? A SER 656 
29  1 Y 1 A LYS 677 ? A LYS 657 
30  1 Y 1 A LYS 678 ? A LYS 658 
31  1 Y 1 A LYS 679 ? A LYS 659 
32  1 Y 1 A ILE 680 ? A ILE 660 
33  1 Y 1 A CYS 681 ? A CYS 661 
34  1 Y 1 A THR 682 ? A THR 662 
35  1 Y 1 A LYS 683 ? A LYS 663 
36  1 Y 1 A LYS 684 ? A LYS 664 
37  1 Y 1 A PRO 685 ? A PRO 665 
38  1 Y 1 A ARG 686 ? A ARG 666 
39  1 Y 1 A PHE 687 ? A PHE 667 
40  1 Y 1 A LYS 828 ? A LYS 808 
41  1 Y 1 A PRO 829 ? A PRO 809 
42  1 Y 1 A GLU 830 ? A GLU 810 
43  1 Y 1 A ARG 831 ? A ARG 811 
44  1 Y 1 A ASN 832 ? A ASN 812 
45  1 Y 1 A VAL 833 ? A VAL 813 
46  1 Y 1 A ARG 834 ? A ARG 814 
47  1 Y 1 A SER 835 ? A SER 815 
48  1 Y 1 A ALA 836 ? A ALA 816 
49  1 Y 1 A PHE 837 ? A PHE 817 
50  1 Y 1 A THR 838 ? A THR 818 
51  1 Y 1 A THR 839 ? A THR 819 
52  1 Y 1 A SER 840 ? A SER 820 
53  1 Y 1 A THR 841 ? A THR 821 
54  1 Y 1 A VAL 842 ? A VAL 822 
55  1 Y 1 A VAL 843 ? A VAL 823 
56  1 Y 1 A ARG 844 ? A ARG 824 
57  1 Y 1 A MET 845 ? A MET 825 
58  1 Y 1 A HIS 846 ? A HIS 826 
59  1 Y 1 A VAL 847 ? A VAL 827 
60  1 Y 1 A GLY 848 ? A GLY 828 
61  1 Y 1 A ASP 849 ? A ASP 829 
62  1 Y 1 A GLY 850 ? A GLY 830 
63  1 Y 1 A LYS 851 ? A LYS 831 
64  1 Y 1 A SER 852 ? A SER 832 
65  1 Y 1 A SER 853 ? A SER 833 
66  1 Y 1 A SER 854 ? A SER 834 
67  1 Y 1 A ALA 855 ? A ALA 835 
68  1 Y 1 A ALA 856 ? A ALA 836 
69  1 Y 1 B GLN 21  ? B GLN 1   
70  1 Y 1 B SER 22  ? B SER 2   
71  1 Y 1 B SER 23  ? B SER 3   
72  1 Y 1 B GLU 24  ? B GLU 4   
73  1 Y 1 B ILE 118 ? B ILE 98  
74  1 Y 1 B SER 119 ? B SER 99  
75  1 Y 1 B SER 120 ? B SER 100 
76  1 Y 1 B GLU 121 ? B GLU 101 
77  1 Y 1 B GLU 122 ? B GLU 102 
78  1 Y 1 B GLU 123 ? B GLU 103 
79  1 Y 1 B GLU 124 ? B GLU 104 
80  1 Y 1 B GLY 125 ? B GLY 105 
81  1 Y 1 B LEU 126 ? B LEU 106 
82  1 Y 1 B VAL 127 ? B VAL 107 
83  1 Y 1 B ARG 128 ? B ARG 108 
84  1 Y 1 B CYS 129 ? B CYS 109 
85  1 Y 1 B VAL 130 ? B VAL 110 
86  1 Y 1 B ASP 131 ? B ASP 111 
87  1 Y 1 B GLY 132 ? B GLY 112 
88  1 Y 1 B SER 133 ? B SER 113 
89  1 Y 1 B SER 134 ? B SER 114 
90  1 Y 1 B SER 135 ? B SER 115 
91  1 Y 1 B SER 136 ? B SER 116 
92  1 Y 1 B PHE 137 ? B PHE 117 
93  1 Y 1 B ARG 138 ? B ARG 118 
94  1 Y 1 B SER 139 ? B SER 119 
95  1 Y 1 B LYS 140 ? B LYS 120 
96  1 Y 1 B SER 676 ? B SER 656 
97  1 Y 1 B LYS 677 ? B LYS 657 
98  1 Y 1 B LYS 678 ? B LYS 658 
99  1 Y 1 B LYS 679 ? B LYS 659 
100 1 Y 1 B ILE 680 ? B ILE 660 
101 1 Y 1 B CYS 681 ? B CYS 661 
102 1 Y 1 B THR 682 ? B THR 662 
103 1 Y 1 B LYS 683 ? B LYS 663 
104 1 Y 1 B LYS 684 ? B LYS 664 
105 1 Y 1 B PRO 685 ? B PRO 665 
106 1 Y 1 B ARG 686 ? B ARG 666 
107 1 Y 1 B PHE 687 ? B PHE 667 
108 1 Y 1 B LYS 828 ? B LYS 808 
109 1 Y 1 B PRO 829 ? B PRO 809 
110 1 Y 1 B GLU 830 ? B GLU 810 
111 1 Y 1 B ARG 831 ? B ARG 811 
112 1 Y 1 B ASN 832 ? B ASN 812 
113 1 Y 1 B VAL 833 ? B VAL 813 
114 1 Y 1 B ARG 834 ? B ARG 814 
115 1 Y 1 B SER 835 ? B SER 815 
116 1 Y 1 B ALA 836 ? B ALA 816 
117 1 Y 1 B PHE 837 ? B PHE 817 
118 1 Y 1 B THR 838 ? B THR 818 
119 1 Y 1 B THR 839 ? B THR 819 
120 1 Y 1 B SER 840 ? B SER 820 
121 1 Y 1 B THR 841 ? B THR 821 
122 1 Y 1 B VAL 842 ? B VAL 822 
123 1 Y 1 B VAL 843 ? B VAL 823 
124 1 Y 1 B ARG 844 ? B ARG 824 
125 1 Y 1 B MET 845 ? B MET 825 
126 1 Y 1 B HIS 846 ? B HIS 826 
127 1 Y 1 B VAL 847 ? B VAL 827 
128 1 Y 1 B GLY 848 ? B GLY 828 
129 1 Y 1 B ASP 849 ? B ASP 829 
130 1 Y 1 B GLY 850 ? B GLY 830 
131 1 Y 1 B LYS 851 ? B LYS 831 
132 1 Y 1 B SER 852 ? B SER 832 
133 1 Y 1 B SER 853 ? B SER 833 
134 1 Y 1 B SER 854 ? B SER 834 
135 1 Y 1 B ALA 855 ? B ALA 835 
136 1 Y 1 B ALA 856 ? B ALA 836 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
NAG C1   C N R 247 
NAG C2   C N R 248 
NAG C3   C N R 249 
NAG C4   C N S 250 
NAG C5   C N R 251 
NAG C6   C N N 252 
NAG C7   C N N 253 
NAG C8   C N N 254 
NAG N2   N N N 255 
NAG O1   O N N 256 
NAG O3   O N N 257 
NAG O4   O N N 258 
NAG O5   O N N 259 
NAG O6   O N N 260 
NAG O7   O N N 261 
NAG H1   H N N 262 
NAG H2   H N N 263 
NAG H3   H N N 264 
NAG H4   H N N 265 
NAG H5   H N N 266 
NAG H61  H N N 267 
NAG H62  H N N 268 
NAG H81  H N N 269 
NAG H82  H N N 270 
NAG H83  H N N 271 
NAG HN2  H N N 272 
NAG HO1  H N N 273 
NAG HO3  H N N 274 
NAG HO4  H N N 275 
NAG HO6  H N N 276 
PHE N    N N N 277 
PHE CA   C N S 278 
PHE C    C N N 279 
PHE O    O N N 280 
PHE CB   C N N 281 
PHE CG   C Y N 282 
PHE CD1  C Y N 283 
PHE CD2  C Y N 284 
PHE CE1  C Y N 285 
PHE CE2  C Y N 286 
PHE CZ   C Y N 287 
PHE OXT  O N N 288 
PHE H    H N N 289 
PHE H2   H N N 290 
PHE HA   H N N 291 
PHE HB2  H N N 292 
PHE HB3  H N N 293 
PHE HD1  H N N 294 
PHE HD2  H N N 295 
PHE HE1  H N N 296 
PHE HE2  H N N 297 
PHE HZ   H N N 298 
PHE HXT  H N N 299 
PRO N    N N N 300 
PRO CA   C N S 301 
PRO C    C N N 302 
PRO O    O N N 303 
PRO CB   C N N 304 
PRO CG   C N N 305 
PRO CD   C N N 306 
PRO OXT  O N N 307 
PRO H    H N N 308 
PRO HA   H N N 309 
PRO HB2  H N N 310 
PRO HB3  H N N 311 
PRO HG2  H N N 312 
PRO HG3  H N N 313 
PRO HD2  H N N 314 
PRO HD3  H N N 315 
PRO HXT  H N N 316 
QUS C01  C N N 317 
QUS C02  C N S 318 
QUS C03  C N N 319 
QUS C04  C Y N 320 
QUS C05  C Y N 321 
QUS NP3  N N N 322 
QUS N14  N Y N 323 
QUS N15  N Y N 324 
QUS O16  O N N 325 
QUS O17  O N N 326 
QUS O18  O N N 327 
QUS O19  O N N 328 
QUS O20  O Y N 329 
QUS H02  H N N 330 
QUS H031 H N N 331 
QUS H032 H N N 332 
QUS HP31 H N N 333 
QUS HP32 H N N 334 
QUS H15  H N N 335 
QUS H17  H N N 336 
SER N    N N N 337 
SER CA   C N S 338 
SER C    C N N 339 
SER O    O N N 340 
SER CB   C N N 341 
SER OG   O N N 342 
SER OXT  O N N 343 
SER H    H N N 344 
SER H2   H N N 345 
SER HA   H N N 346 
SER HB2  H N N 347 
SER HB3  H N N 348 
SER HG   H N N 349 
SER HXT  H N N 350 
THR N    N N N 351 
THR CA   C N S 352 
THR C    C N N 353 
THR O    O N N 354 
THR CB   C N R 355 
THR OG1  O N N 356 
THR CG2  C N N 357 
THR OXT  O N N 358 
THR H    H N N 359 
THR H2   H N N 360 
THR HA   H N N 361 
THR HB   H N N 362 
THR HG1  H N N 363 
THR HG21 H N N 364 
THR HG22 H N N 365 
THR HG23 H N N 366 
THR HXT  H N N 367 
TRP N    N N N 368 
TRP CA   C N S 369 
TRP C    C N N 370 
TRP O    O N N 371 
TRP CB   C N N 372 
TRP CG   C Y N 373 
TRP CD1  C Y N 374 
TRP CD2  C Y N 375 
TRP NE1  N Y N 376 
TRP CE2  C Y N 377 
TRP CE3  C Y N 378 
TRP CZ2  C Y N 379 
TRP CZ3  C Y N 380 
TRP CH2  C Y N 381 
TRP OXT  O N N 382 
TRP H    H N N 383 
TRP H2   H N N 384 
TRP HA   H N N 385 
TRP HB2  H N N 386 
TRP HB3  H N N 387 
TRP HD1  H N N 388 
TRP HE1  H N N 389 
TRP HE3  H N N 390 
TRP HZ2  H N N 391 
TRP HZ3  H N N 392 
TRP HH2  H N N 393 
TRP HXT  H N N 394 
TYR N    N N N 395 
TYR CA   C N S 396 
TYR C    C N N 397 
TYR O    O N N 398 
TYR CB   C N N 399 
TYR CG   C Y N 400 
TYR CD1  C Y N 401 
TYR CD2  C Y N 402 
TYR CE1  C Y N 403 
TYR CE2  C Y N 404 
TYR CZ   C Y N 405 
TYR OH   O N N 406 
TYR OXT  O N N 407 
TYR H    H N N 408 
TYR H2   H N N 409 
TYR HA   H N N 410 
TYR HB2  H N N 411 
TYR HB3  H N N 412 
TYR HD1  H N N 413 
TYR HD2  H N N 414 
TYR HE1  H N N 415 
TYR HE2  H N N 416 
TYR HH   H N N 417 
TYR HXT  H N N 418 
VAL N    N N N 419 
VAL CA   C N S 420 
VAL C    C N N 421 
VAL O    O N N 422 
VAL CB   C N N 423 
VAL CG1  C N N 424 
VAL CG2  C N N 425 
VAL OXT  O N N 426 
VAL H    H N N 427 
VAL H2   H N N 428 
VAL HA   H N N 429 
VAL HB   H N N 430 
VAL HG11 H N N 431 
VAL HG12 H N N 432 
VAL HG13 H N N 433 
VAL HG21 H N N 434 
VAL HG22 H N N 435 
VAL HG23 H N N 436 
VAL HXT  H N N 437 
XQT O1   O N N 438 
XQT C1   C N N 439 
XQT C2   C N R 440 
XQT C3   C N N 441 
XQT C4   C N N 442 
XQT C5   C N N 443 
XQT N1   N N N 444 
XQT C6   C N N 445 
XQT C7   C Y N 446 
XQT C8   C Y N 447 
XQT C9   C Y N 448 
XQT C10  C Y N 449 
XQT C11  C N N 450 
XQT C12  C N N 451 
XQT C13  C Y N 452 
XQT C14  C Y N 453 
XQT C15  C Y N 454 
XQT F1   F N N 455 
XQT C16  C Y N 456 
XQT C17  C Y N 457 
XQT C18  C Y N 458 
XQT C19  C Y N 459 
XQT N2   N Y N 460 
XQT O2   O N N 461 
XQT H1   H N N 462 
XQT H2   H N N 463 
XQT H3   H N N 464 
XQT H4   H N N 465 
XQT H5   H N N 466 
XQT H6   H N N 467 
XQT H7   H N N 468 
XQT H8   H N N 469 
XQT H9   H N N 470 
XQT H10  H N N 471 
XQT H11  H N N 472 
XQT H12  H N N 473 
XQT H13  H N N 474 
XQT H14  H N N 475 
XQT H15  H N N 476 
XQT H16  H N N 477 
XQT H17  H N N 478 
XQT H18  H N N 479 
XQT H19  H N N 480 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAG C1  C2   sing N N 235 
NAG C1  O1   sing N N 236 
NAG C1  O5   sing N N 237 
NAG C1  H1   sing N N 238 
NAG C2  C3   sing N N 239 
NAG C2  N2   sing N N 240 
NAG C2  H2   sing N N 241 
NAG C3  C4   sing N N 242 
NAG C3  O3   sing N N 243 
NAG C3  H3   sing N N 244 
NAG C4  C5   sing N N 245 
NAG C4  O4   sing N N 246 
NAG C4  H4   sing N N 247 
NAG C5  C6   sing N N 248 
NAG C5  O5   sing N N 249 
NAG C5  H5   sing N N 250 
NAG C6  O6   sing N N 251 
NAG C6  H61  sing N N 252 
NAG C6  H62  sing N N 253 
NAG C7  C8   sing N N 254 
NAG C7  N2   sing N N 255 
NAG C7  O7   doub N N 256 
NAG C8  H81  sing N N 257 
NAG C8  H82  sing N N 258 
NAG C8  H83  sing N N 259 
NAG N2  HN2  sing N N 260 
NAG O1  HO1  sing N N 261 
NAG O3  HO3  sing N N 262 
NAG O4  HO4  sing N N 263 
NAG O6  HO6  sing N N 264 
PHE N   CA   sing N N 265 
PHE N   H    sing N N 266 
PHE N   H2   sing N N 267 
PHE CA  C    sing N N 268 
PHE CA  CB   sing N N 269 
PHE CA  HA   sing N N 270 
PHE C   O    doub N N 271 
PHE C   OXT  sing N N 272 
PHE CB  CG   sing N N 273 
PHE CB  HB2  sing N N 274 
PHE CB  HB3  sing N N 275 
PHE CG  CD1  doub Y N 276 
PHE CG  CD2  sing Y N 277 
PHE CD1 CE1  sing Y N 278 
PHE CD1 HD1  sing N N 279 
PHE CD2 CE2  doub Y N 280 
PHE CD2 HD2  sing N N 281 
PHE CE1 CZ   doub Y N 282 
PHE CE1 HE1  sing N N 283 
PHE CE2 CZ   sing Y N 284 
PHE CE2 HE2  sing N N 285 
PHE CZ  HZ   sing N N 286 
PHE OXT HXT  sing N N 287 
PRO N   CA   sing N N 288 
PRO N   CD   sing N N 289 
PRO N   H    sing N N 290 
PRO CA  C    sing N N 291 
PRO CA  CB   sing N N 292 
PRO CA  HA   sing N N 293 
PRO C   O    doub N N 294 
PRO C   OXT  sing N N 295 
PRO CB  CG   sing N N 296 
PRO CB  HB2  sing N N 297 
PRO CB  HB3  sing N N 298 
PRO CG  CD   sing N N 299 
PRO CG  HG2  sing N N 300 
PRO CG  HG3  sing N N 301 
PRO CD  HD2  sing N N 302 
PRO CD  HD3  sing N N 303 
PRO OXT HXT  sing N N 304 
QUS C01 C02  sing N N 305 
QUS C01 O16  doub N N 306 
QUS C01 O17  sing N N 307 
QUS C02 C03  sing N N 308 
QUS C02 NP3  sing N N 309 
QUS C02 H02  sing N N 310 
QUS C03 N14  sing N N 311 
QUS C03 H031 sing N N 312 
QUS C03 H032 sing N N 313 
QUS C04 N14  sing Y N 314 
QUS C04 N15  sing Y N 315 
QUS C04 O18  doub N N 316 
QUS C05 N15  sing Y N 317 
QUS C05 O19  doub N N 318 
QUS C05 O20  sing Y N 319 
QUS NP3 HP31 sing N N 320 
QUS NP3 HP32 sing N N 321 
QUS N14 O20  sing Y N 322 
QUS N15 H15  sing N N 323 
QUS O17 H17  sing N N 324 
SER N   CA   sing N N 325 
SER N   H    sing N N 326 
SER N   H2   sing N N 327 
SER CA  C    sing N N 328 
SER CA  CB   sing N N 329 
SER CA  HA   sing N N 330 
SER C   O    doub N N 331 
SER C   OXT  sing N N 332 
SER CB  OG   sing N N 333 
SER CB  HB2  sing N N 334 
SER CB  HB3  sing N N 335 
SER OG  HG   sing N N 336 
SER OXT HXT  sing N N 337 
THR N   CA   sing N N 338 
THR N   H    sing N N 339 
THR N   H2   sing N N 340 
THR CA  C    sing N N 341 
THR CA  CB   sing N N 342 
THR CA  HA   sing N N 343 
THR C   O    doub N N 344 
THR C   OXT  sing N N 345 
THR CB  OG1  sing N N 346 
THR CB  CG2  sing N N 347 
THR CB  HB   sing N N 348 
THR OG1 HG1  sing N N 349 
THR CG2 HG21 sing N N 350 
THR CG2 HG22 sing N N 351 
THR CG2 HG23 sing N N 352 
THR OXT HXT  sing N N 353 
TRP N   CA   sing N N 354 
TRP N   H    sing N N 355 
TRP N   H2   sing N N 356 
TRP CA  C    sing N N 357 
TRP CA  CB   sing N N 358 
TRP CA  HA   sing N N 359 
TRP C   O    doub N N 360 
TRP C   OXT  sing N N 361 
TRP CB  CG   sing N N 362 
TRP CB  HB2  sing N N 363 
TRP CB  HB3  sing N N 364 
TRP CG  CD1  doub Y N 365 
TRP CG  CD2  sing Y N 366 
TRP CD1 NE1  sing Y N 367 
TRP CD1 HD1  sing N N 368 
TRP CD2 CE2  doub Y N 369 
TRP CD2 CE3  sing Y N 370 
TRP NE1 CE2  sing Y N 371 
TRP NE1 HE1  sing N N 372 
TRP CE2 CZ2  sing Y N 373 
TRP CE3 CZ3  doub Y N 374 
TRP CE3 HE3  sing N N 375 
TRP CZ2 CH2  doub Y N 376 
TRP CZ2 HZ2  sing N N 377 
TRP CZ3 CH2  sing Y N 378 
TRP CZ3 HZ3  sing N N 379 
TRP CH2 HH2  sing N N 380 
TRP OXT HXT  sing N N 381 
TYR N   CA   sing N N 382 
TYR N   H    sing N N 383 
TYR N   H2   sing N N 384 
TYR CA  C    sing N N 385 
TYR CA  CB   sing N N 386 
TYR CA  HA   sing N N 387 
TYR C   O    doub N N 388 
TYR C   OXT  sing N N 389 
TYR CB  CG   sing N N 390 
TYR CB  HB2  sing N N 391 
TYR CB  HB3  sing N N 392 
TYR CG  CD1  doub Y N 393 
TYR CG  CD2  sing Y N 394 
TYR CD1 CE1  sing Y N 395 
TYR CD1 HD1  sing N N 396 
TYR CD2 CE2  doub Y N 397 
TYR CD2 HD2  sing N N 398 
TYR CE1 CZ   doub Y N 399 
TYR CE1 HE1  sing N N 400 
TYR CE2 CZ   sing Y N 401 
TYR CE2 HE2  sing N N 402 
TYR CZ  OH   sing N N 403 
TYR OH  HH   sing N N 404 
TYR OXT HXT  sing N N 405 
VAL N   CA   sing N N 406 
VAL N   H    sing N N 407 
VAL N   H2   sing N N 408 
VAL CA  C    sing N N 409 
VAL CA  CB   sing N N 410 
VAL CA  HA   sing N N 411 
VAL C   O    doub N N 412 
VAL C   OXT  sing N N 413 
VAL CB  CG1  sing N N 414 
VAL CB  CG2  sing N N 415 
VAL CB  HB   sing N N 416 
VAL CG1 HG11 sing N N 417 
VAL CG1 HG12 sing N N 418 
VAL CG1 HG13 sing N N 419 
VAL CG2 HG21 sing N N 420 
VAL CG2 HG22 sing N N 421 
VAL CG2 HG23 sing N N 422 
VAL OXT HXT  sing N N 423 
XQT C1  C2   sing N N 424 
XQT C4  C3   sing N N 425 
XQT C2  C3   sing N N 426 
XQT C2  N1   sing N N 427 
XQT O2  C6   doub N N 428 
XQT C3  O1   sing N N 429 
XQT C3  C5   sing N N 430 
XQT N1  C6   sing N N 431 
XQT C6  C7   sing N N 432 
XQT C7  C8   doub Y N 433 
XQT C7  N2   sing Y N 434 
XQT C8  C9   sing Y N 435 
XQT N2  C19  doub Y N 436 
XQT C9  C10  doub Y N 437 
XQT C19 C10  sing Y N 438 
XQT C10 C11  sing N N 439 
XQT C11 C12  trip N N 440 
XQT C12 C13  sing N N 441 
XQT C14 C13  doub Y N 442 
XQT C14 C15  sing Y N 443 
XQT C13 C18  sing Y N 444 
XQT F1  C15  sing N N 445 
XQT C15 C16  doub Y N 446 
XQT C18 C17  doub Y N 447 
XQT C16 C17  sing Y N 448 
XQT O1  H1   sing N N 449 
XQT C1  H2   sing N N 450 
XQT C1  H3   sing N N 451 
XQT C1  H4   sing N N 452 
XQT C2  H5   sing N N 453 
XQT C4  H6   sing N N 454 
XQT C4  H7   sing N N 455 
XQT C4  H8   sing N N 456 
XQT C5  H9   sing N N 457 
XQT C5  H10  sing N N 458 
XQT C5  H11  sing N N 459 
XQT N1  H12  sing N N 460 
XQT C8  H13  sing N N 461 
XQT C9  H14  sing N N 462 
XQT C14 H15  sing N N 463 
XQT C16 H16  sing N N 464 
XQT C17 H17  sing N N 465 
XQT C18 H18  sing N N 466 
XQT C19 H19  sing N N 467 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-11-04 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8X0D 
_em_admin.last_update        2025-01-29 
_em_admin.map_release_date   2024-11-06 
_em_admin.title              'Human FL Metabotropic glutamate receptor 5, mGlu5-5M with quisqualate and VU0424465, conformer 2' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 25    mM ? 1 HEPES                       
1 150   mM ? 2 'sodium chloride'           
1 0.03  %  ? 3 'dodecyl maltpside'         
1 0.006 %  ? 4 'cholesterol hemisuccinate' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.2 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 'HEK293S GnTI-' 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              BAcMaM 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               4.9 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             'Electron flux was 5.4 /e/A2/s. No. of frames 1566' 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     19115 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   4481289 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? Topaz          ?           
'IMAGE ACQUISITION'             ? 2  ? ? 1 EPU            ?           
MASKING                         ? 3  ? ? ? ?              ?           
'CTF CORRECTION'                ? 4  1 ? ? CTFFIND        4.1.14      
'CTF CORRECTION'                ? 5  1 ? ? RELION         4.0         
'CTF CORRECTION'                ? 6  1 ? ? cryoSPARC      ?           
'LAYERLINE INDEXING'            ? 7  ? ? ? ?              ?           
'DIFFRACTION INDEXING'          ? 8  ? ? ? ?              ?           
'MODEL FITTING'                 ? 9  ? 1 ? 'UCSF Chimera' 1.15        
'MODEL FITTING'                 ? 10 ? 1 ? Coot           0.9.8.7     
OTHER                           ? 11 ? ? ? ?              ?           
'INITIAL EULER ASSIGNMENT'      ? 12 1 ? ? ?              ?           
'FINAL EULER ASSIGNMENT'        ? 13 1 ? ? ?              ?           
CLASSIFICATION                  ? 14 1 ? ? ?              ?           
RECONSTRUCTION                  ? 15 1 ? ? cryoSPARC      ?           
'VOLUME SELECTION'              ? 16 1 1 1 ?              ?           
'SERIES ALIGNMENT'              ? 17 1 1 1 ?              ?           
'MOLECULAR REPLACEMENT'         ? 18 1 1 1 ?              ?           
'LATTICE DISTORTION CORRECTION' ? 19 1 1 1 ?              ?           
'SYMMETRY DETERMINATION'        ? 20 1 1 1 ?              ?           
'CRYSTALLOGRAPHY MERGING'       ? 21 1 1 1 ?              ?           
'MODEL REFINEMENT'              ? 22 ? 1 ? PHENIX         1.20.1-4487 
'MODEL REFINEMENT'              ? 23 ? 1 ? REFMAC         5.8.0411    
# 
_em_specimen.concentration           6 
_em_specimen.details                 
;Receptor is purified in detergent micelles and monodisperse. The receptor is purified with 10 uM Quisqualate and 10 uM PAM VU0424465
;
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Department of Biotechnology (DBT, India)' India  DBT/PR12422/MED/31/287/204 1 
'Other government'                         ?      RTI4006                    2 
'Agence Nationale de la Recherche (ANR)'   France ANR-20-CE11-0019           3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             other 
_pdbx_initial_refinement_model.source_name      Other 
_pdbx_initial_refinement_model.accession_code   D_1300042377 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8X0D 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
F 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . ARG A 1 5   ? 115.732 137.670 50.512  1.00 115.82 ? 25  ARG A N   1 
ATOM   2     C CA  . ARG A 1 5   ? 117.055 138.020 51.101  1.00 115.95 ? 25  ARG A CA  1 
ATOM   3     C C   . ARG A 1 5   ? 116.972 139.403 51.742  1.00 109.32 ? 25  ARG A C   1 
ATOM   4     O O   . ARG A 1 5   ? 116.144 140.224 51.351  1.00 110.81 ? 25  ARG A O   1 
ATOM   5     C CB  . ARG A 1 5   ? 118.167 137.978 50.044  1.00 120.12 ? 25  ARG A CB  1 
ATOM   6     C CG  . ARG A 1 5   ? 117.899 138.811 48.797  1.00 125.00 ? 25  ARG A CG  1 
ATOM   7     C CD  . ARG A 1 5   ? 119.032 138.724 47.793  1.00 129.97 ? 25  ARG A CD  1 
ATOM   8     N NE  . ARG A 1 5   ? 118.690 139.355 46.524  1.00 135.05 ? 25  ARG A NE  1 
ATOM   9     C CZ  . ARG A 1 5   ? 119.477 139.392 45.451  1.00 139.11 ? 25  ARG A CZ  1 
ATOM   10    N NH1 . ARG A 1 5   ? 120.680 138.843 45.479  1.00 138.85 ? 25  ARG A NH1 1 
ATOM   11    N NH2 . ARG A 1 5   ? 119.054 139.983 44.345  1.00 139.90 ? 25  ARG A NH2 1 
ATOM   12    N N   . ARG A 1 6   ? 117.850 139.650 52.721  1.00 99.14  ? 26  ARG A N   1 
ATOM   13    C CA  . ARG A 1 6   ? 117.897 140.936 53.401  1.00 92.30  ? 26  ARG A CA  1 
ATOM   14    C C   . ARG A 1 6   ? 118.522 141.984 52.485  1.00 88.44  ? 26  ARG A C   1 
ATOM   15    O O   . ARG A 1 6   ? 119.367 141.669 51.647  1.00 88.69  ? 26  ARG A O   1 
ATOM   16    C CB  . ARG A 1 6   ? 118.690 140.846 54.707  1.00 90.04  ? 26  ARG A CB  1 
ATOM   17    C CG  . ARG A 1 6   ? 117.917 140.230 55.861  1.00 87.59  ? 26  ARG A CG  1 
ATOM   18    C CD  . ARG A 1 6   ? 118.684 140.375 57.160  1.00 85.32  ? 26  ARG A CD  1 
ATOM   19    N NE  . ARG A 1 6   ? 117.898 139.994 58.319  1.00 83.92  ? 26  ARG A NE  1 
ATOM   20    C CZ  . ARG A 1 6   ? 117.473 138.765 58.590  1.00 83.57  ? 26  ARG A CZ  1 
ATOM   21    N NH1 . ARG A 1 6   ? 117.795 137.754 57.804  1.00 83.56  ? 26  ARG A NH1 1 
ATOM   22    N NH2 . ARG A 1 6   ? 116.724 138.547 59.659  1.00 82.69  ? 26  ARG A NH2 1 
ATOM   23    N N   . VAL A 1 7   ? 118.092 143.236 52.669  1.00 83.02  ? 27  VAL A N   1 
ATOM   24    C CA  . VAL A 1 7   ? 118.583 144.356 51.883  1.00 79.39  ? 27  VAL A CA  1 
ATOM   25    C C   . VAL A 1 7   ? 119.853 144.892 52.541  1.00 75.63  ? 27  VAL A C   1 
ATOM   26    O O   . VAL A 1 7   ? 120.002 144.810 53.758  1.00 74.58  ? 27  VAL A O   1 
ATOM   27    C CB  . VAL A 1 7   ? 117.509 145.452 51.733  1.00 79.85  ? 27  VAL A CB  1 
ATOM   28    C CG1 . VAL A 1 7   ? 117.182 146.132 53.055  1.00 79.35  ? 27  VAL A CG1 1 
ATOM   29    C CG2 . VAL A 1 7   ? 117.898 146.485 50.686  1.00 80.40  ? 27  VAL A CG2 1 
ATOM   30    N N   . VAL A 1 8   ? 120.753 145.449 51.720  1.00 73.44  ? 28  VAL A N   1 
ATOM   31    C CA  . VAL A 1 8   ? 122.029 145.955 52.198  1.00 71.94  ? 28  VAL A CA  1 
ATOM   32    C C   . VAL A 1 8   ? 122.297 147.325 51.584  1.00 71.46  ? 28  VAL A C   1 
ATOM   33    O O   . VAL A 1 8   ? 121.778 147.649 50.515  1.00 72.02  ? 28  VAL A O   1 
ATOM   34    C CB  . VAL A 1 8   ? 123.184 144.984 51.885  1.00 71.03  ? 28  VAL A CB  1 
ATOM   35    C CG1 . VAL A 1 8   ? 122.826 143.546 52.220  1.00 70.71  ? 28  VAL A CG1 1 
ATOM   36    C CG2 . VAL A 1 8   ? 123.661 145.086 50.443  1.00 70.64  ? 28  VAL A CG2 1 
ATOM   37    N N   . ALA A 1 9   ? 123.171 148.097 52.240  1.00 72.18  ? 29  ALA A N   1 
ATOM   38    C CA  . ALA A 1 9   ? 123.618 149.369 51.697  1.00 74.57  ? 29  ALA A CA  1 
ATOM   39    C C   . ALA A 1 9   ? 124.808 149.146 50.766  1.00 79.67  ? 29  ALA A C   1 
ATOM   40    O O   . ALA A 1 9   ? 125.540 148.162 50.877  1.00 80.44  ? 29  ALA A O   1 
ATOM   41    C CB  . ALA A 1 9   ? 123.950 150.333 52.809  1.00 73.47  ? 29  ALA A CB  1 
ATOM   42    N N   . HIS A 1 10  ? 124.983 150.070 49.820  1.00 85.63  ? 30  HIS A N   1 
ATOM   43    C CA  . HIS A 1 10  ? 126.098 150.002 48.889  1.00 90.38  ? 30  HIS A CA  1 
ATOM   44    C C   . HIS A 1 10  ? 126.737 151.375 48.755  1.00 90.91  ? 30  HIS A C   1 
ATOM   45    O O   . HIS A 1 10  ? 126.064 152.397 48.872  1.00 92.83  ? 30  HIS A O   1 
ATOM   46    C CB  . HIS A 1 10  ? 125.659 149.500 47.508  1.00 95.19  ? 30  HIS A CB  1 
ATOM   47    C CG  . HIS A 1 10  ? 125.448 148.024 47.450  1.00 102.22 ? 30  HIS A CG  1 
ATOM   48    N ND1 . HIS A 1 10  ? 126.333 147.129 48.012  1.00 105.69 ? 30  HIS A ND1 1 
ATOM   49    C CD2 . HIS A 1 10  ? 124.454 147.290 46.937  1.00 106.65 ? 30  HIS A CD2 1 
ATOM   50    C CE1 . HIS A 1 10  ? 125.889 145.896 47.817  1.00 107.67 ? 30  HIS A CE1 1 
ATOM   51    N NE2 . HIS A 1 10  ? 124.752 145.970 47.158  1.00 108.19 ? 30  HIS A NE2 1 
ATOM   52    N N   . MET A 1 11  ? 128.048 151.372 48.503  1.00 90.74  ? 31  MET A N   1 
ATOM   53    C CA  . MET A 1 11  ? 128.750 152.581 48.116  1.00 91.61  ? 31  MET A CA  1 
ATOM   54    C C   . MET A 1 11  ? 129.975 152.179 47.301  1.00 92.26  ? 31  MET A C   1 
ATOM   55    O O   . MET A 1 11  ? 130.813 151.419 47.780  1.00 92.07  ? 31  MET A O   1 
ATOM   56    C CB  . MET A 1 11  ? 129.180 153.380 49.347  1.00 91.78  ? 31  MET A CB  1 
ATOM   57    C CG  . MET A 1 11  ? 129.889 154.678 49.026  1.00 94.77  ? 31  MET A CG  1 
ATOM   58    S SD  . MET A 1 11  ? 129.962 155.729 50.506  1.00 98.97  ? 31  MET A SD  1 
ATOM   59    C CE  . MET A 1 11  ? 129.962 157.366 49.775  1.00 99.93  ? 31  MET A CE  1 
ATOM   60    N N   . PRO A 1 12  ? 130.091 152.639 46.035  1.00 93.59  ? 32  PRO A N   1 
ATOM   61    C CA  . PRO A 1 12  ? 131.170 152.189 45.156  1.00 94.02  ? 32  PRO A CA  1 
ATOM   62    C C   . PRO A 1 12  ? 132.527 152.676 45.652  1.00 94.13  ? 32  PRO A C   1 
ATOM   63    O O   . PRO A 1 12  ? 132.618 153.717 46.301  1.00 94.36  ? 32  PRO A O   1 
ATOM   64    C CB  . PRO A 1 12  ? 130.818 152.799 43.792  1.00 95.37  ? 32  PRO A CB  1 
ATOM   65    C CG  . PRO A 1 12  ? 129.963 154.005 44.133  1.00 95.97  ? 32  PRO A CG  1 
ATOM   66    C CD  . PRO A 1 12  ? 129.206 153.621 45.386  1.00 95.04  ? 32  PRO A CD  1 
ATOM   67    N N   . GLY A 1 13  ? 133.569 151.899 45.348  1.00 94.73  ? 33  GLY A N   1 
ATOM   68    C CA  . GLY A 1 13  ? 134.924 152.256 45.725  1.00 95.57  ? 33  GLY A CA  1 
ATOM   69    C C   . GLY A 1 13  ? 135.938 151.222 45.245  1.00 95.77  ? 33  GLY A C   1 
ATOM   70    O O   . GLY A 1 13  ? 135.566 150.136 44.814  1.00 95.93  ? 33  GLY A O   1 
ATOM   71    N N   . ASP A 1 14  ? 137.219 151.590 45.328  1.00 94.69  ? 34  ASP A N   1 
ATOM   72    C CA  . ASP A 1 14  ? 138.313 150.727 44.916  1.00 94.00  ? 34  ASP A CA  1 
ATOM   73    C C   . ASP A 1 14  ? 138.535 149.641 45.965  1.00 86.68  ? 34  ASP A C   1 
ATOM   74    O O   . ASP A 1 14  ? 138.771 148.486 45.612  1.00 85.70  ? 34  ASP A O   1 
ATOM   75    C CB  . ASP A 1 14  ? 139.596 151.527 44.680  1.00 98.96  ? 34  ASP A CB  1 
ATOM   76    C CG  . ASP A 1 14  ? 139.907 151.784 43.215  1.00 103.50 ? 34  ASP A CG  1 
ATOM   77    O OD1 . ASP A 1 14  ? 139.123 151.325 42.362  1.00 104.68 ? 34  ASP A OD1 1 
ATOM   78    O OD2 . ASP A 1 14  ? 140.942 152.420 42.943  1.00 105.10 ? 34  ASP A OD2 1 
ATOM   79    N N   . ILE A 1 15  ? 138.467 150.028 47.246  1.00 79.64  ? 35  ILE A N   1 
ATOM   80    C CA  . ILE A 1 15  ? 138.568 149.088 48.352  1.00 73.25  ? 35  ILE A CA  1 
ATOM   81    C C   . ILE A 1 15  ? 137.230 149.077 49.087  1.00 67.71  ? 35  ILE A C   1 
ATOM   82    O O   . ILE A 1 15  ? 136.729 150.134 49.464  1.00 68.93  ? 35  ILE A O   1 
ATOM   83    C CB  . ILE A 1 15  ? 139.733 149.463 49.292  1.00 71.93  ? 35  ILE A CB  1 
ATOM   84    C CG1 . ILE A 1 15  ? 141.011 149.785 48.512  1.00 73.05  ? 35  ILE A CG1 1 
ATOM   85    C CG2 . ILE A 1 15  ? 139.966 148.372 50.326  1.00 70.49  ? 35  ILE A CG2 1 
ATOM   86    C CD1 . ILE A 1 15  ? 142.154 150.280 49.370  1.00 74.16  ? 35  ILE A CD1 1 
ATOM   87    N N   . ILE A 1 16  ? 136.666 147.878 49.282  1.00 60.50  ? 36  ILE A N   1 
ATOM   88    C CA  . ILE A 1 16  ? 135.353 147.742 49.886  1.00 55.97  ? 36  ILE A CA  1 
ATOM   89    C C   . ILE A 1 16  ? 135.501 147.231 51.316  1.00 51.27  ? 36  ILE A C   1 
ATOM   90    O O   . ILE A 1 16  ? 136.045 146.156 51.551  1.00 51.33  ? 36  ILE A O   1 
ATOM   91    C CB  . ILE A 1 16  ? 134.440 146.836 49.037  1.00 56.72  ? 36  ILE A CB  1 
ATOM   92    C CG1 . ILE A 1 16  ? 134.328 147.360 47.601  1.00 58.24  ? 36  ILE A CG1 1 
ATOM   93    C CG2 . ILE A 1 16  ? 133.081 146.670 49.707  1.00 56.74  ? 36  ILE A CG2 1 
ATOM   94    C CD1 . ILE A 1 16  ? 133.169 146.793 46.805  1.00 59.61  ? 36  ILE A CD1 1 
ATOM   95    N N   . ILE A 1 17  ? 134.973 148.021 52.257  1.00 47.06  ? 37  ILE A N   1 
ATOM   96    C CA  . ILE A 1 17  ? 134.963 147.690 53.671  1.00 43.78  ? 37  ILE A CA  1 
ATOM   97    C C   . ILE A 1 17  ? 133.556 147.225 54.040  1.00 40.67  ? 37  ILE A C   1 
ATOM   98    O O   . ILE A 1 17  ? 132.578 147.720 53.484  1.00 41.13  ? 37  ILE A O   1 
ATOM   99    C CB  . ILE A 1 17  ? 135.415 148.910 54.501  1.00 44.01  ? 37  ILE A CB  1 
ATOM   100   C CG1 . ILE A 1 17  ? 135.747 148.520 55.944  1.00 44.28  ? 37  ILE A CG1 1 
ATOM   101   C CG2 . ILE A 1 17  ? 134.396 150.043 54.434  1.00 44.31  ? 37  ILE A CG2 1 
ATOM   102   C CD1 . ILE A 1 17  ? 136.101 149.692 56.833  1.00 44.25  ? 37  ILE A CD1 1 
ATOM   103   N N   . GLY A 1 18  ? 133.455 146.264 54.960  1.00 37.76  ? 38  GLY A N   1 
ATOM   104   C CA  . GLY A 1 18  ? 132.164 145.753 55.395  1.00 35.46  ? 38  GLY A CA  1 
ATOM   105   C C   . GLY A 1 18  ? 131.774 146.332 56.749  1.00 33.13  ? 38  GLY A C   1 
ATOM   106   O O   . GLY A 1 18  ? 132.620 146.850 57.467  1.00 33.12  ? 38  GLY A O   1 
ATOM   107   N N   . ALA A 1 19  ? 130.485 146.248 57.092  1.00 30.57  ? 39  ALA A N   1 
ATOM   108   C CA  . ALA A 1 19  ? 130.029 146.682 58.400  1.00 28.64  ? 39  ALA A CA  1 
ATOM   109   C C   . ALA A 1 19  ? 128.783 145.911 58.809  1.00 27.18  ? 39  ALA A C   1 
ATOM   110   O O   . ALA A 1 19  ? 127.993 145.521 57.960  1.00 27.52  ? 39  ALA A O   1 
ATOM   111   C CB  . ALA A 1 19  ? 129.768 148.160 58.376  1.00 28.83  ? 39  ALA A CB  1 
ATOM   112   N N   . LEU A 1 20  ? 128.629 145.703 60.119  1.00 26.23  ? 40  LEU A N   1 
ATOM   113   C CA  . LEU A 1 20  ? 127.468 145.024 60.669  1.00 25.78  ? 40  LEU A CA  1 
ATOM   114   C C   . LEU A 1 20  ? 126.845 145.906 61.743  1.00 25.43  ? 40  LEU A C   1 
ATOM   115   O O   . LEU A 1 20  ? 127.395 146.027 62.832  1.00 25.59  ? 40  LEU A O   1 
ATOM   116   C CB  . LEU A 1 20  ? 127.895 143.674 61.254  1.00 25.75  ? 40  LEU A CB  1 
ATOM   117   C CG  . LEU A 1 20  ? 128.018 142.518 60.263  1.00 25.76  ? 40  LEU A CG  1 
ATOM   118   C CD1 . LEU A 1 20  ? 128.632 141.306 60.934  1.00 25.66  ? 40  LEU A CD1 1 
ATOM   119   C CD2 . LEU A 1 20  ? 126.670 142.147 59.669  1.00 25.79  ? 40  LEU A CD2 1 
ATOM   120   N N   . PHE A 1 21  ? 125.706 146.521 61.415  1.00 25.16  ? 41  PHE A N   1 
ATOM   121   C CA  . PHE A 1 21  ? 125.002 147.376 62.355  1.00 25.12  ? 41  PHE A CA  1 
ATOM   122   C C   . PHE A 1 21  ? 123.640 146.768 62.668  1.00 26.03  ? 41  PHE A C   1 
ATOM   123   O O   . PHE A 1 21  ? 122.969 146.240 61.785  1.00 26.77  ? 41  PHE A O   1 
ATOM   124   C CB  . PHE A 1 21  ? 124.867 148.790 61.790  1.00 24.57  ? 41  PHE A CB  1 
ATOM   125   C CG  . PHE A 1 21  ? 126.182 149.478 61.531  1.00 24.08  ? 41  PHE A CG  1 
ATOM   126   C CD1 . PHE A 1 21  ? 127.097 149.670 62.553  1.00 23.78  ? 41  PHE A CD1 1 
ATOM   127   C CD2 . PHE A 1 21  ? 126.506 149.937 60.266  1.00 23.97  ? 41  PHE A CD2 1 
ATOM   128   C CE1 . PHE A 1 21  ? 128.308 150.300 62.315  1.00 23.54  ? 41  PHE A CE1 1 
ATOM   129   C CE2 . PHE A 1 21  ? 127.716 150.567 60.027  1.00 23.79  ? 41  PHE A CE2 1 
ATOM   130   C CZ  . PHE A 1 21  ? 128.614 150.750 61.052  1.00 23.58  ? 41  PHE A CZ  1 
ATOM   131   N N   . SER A 1 22  ? 123.245 146.848 63.943  1.00 26.41  ? 42  SER A N   1 
ATOM   132   C CA  . SER A 1 22  ? 121.957 146.342 64.384  1.00 26.56  ? 42  SER A CA  1 
ATOM   133   C C   . SER A 1 22  ? 120.872 147.334 63.994  1.00 26.58  ? 42  SER A C   1 
ATOM   134   O O   . SER A 1 22  ? 120.403 148.104 64.825  1.00 26.93  ? 42  SER A O   1 
ATOM   135   C CB  . SER A 1 22  ? 121.947 146.085 65.864  1.00 26.99  ? 42  SER A CB  1 
ATOM   136   O OG  . SER A 1 22  ? 122.112 147.290 66.592  1.00 27.31  ? 42  SER A OG  1 
ATOM   137   N N   . VAL A 1 23  ? 120.479 147.296 62.723  1.00 27.36  ? 43  VAL A N   1 
ATOM   138   C CA  . VAL A 1 23  ? 119.493 148.228 62.210  1.00 28.53  ? 43  VAL A CA  1 
ATOM   139   C C   . VAL A 1 23  ? 118.137 147.913 62.837  1.00 29.99  ? 43  VAL A C   1 
ATOM   140   O O   . VAL A 1 23  ? 117.390 148.828 63.175  1.00 30.57  ? 43  VAL A O   1 
ATOM   141   C CB  . VAL A 1 23  ? 119.423 148.176 60.675  1.00 28.99  ? 43  VAL A CB  1 
ATOM   142   C CG1 . VAL A 1 23  ? 118.511 149.265 60.143  1.00 29.35  ? 43  VAL A CG1 1 
ATOM   143   C CG2 . VAL A 1 23  ? 120.798 148.273 60.034  1.00 29.19  ? 43  VAL A CG2 1 
ATOM   144   N N   . HIS A 1 24  ? 117.833 146.614 62.980  1.00 31.49  ? 44  HIS A N   1 
ATOM   145   C CA  . HIS A 1 24  ? 116.572 146.162 63.546  1.00 32.54  ? 44  HIS A CA  1 
ATOM   146   C C   . HIS A 1 24  ? 116.807 145.585 64.937  1.00 33.46  ? 44  HIS A C   1 
ATOM   147   O O   . HIS A 1 24  ? 117.942 145.335 65.329  1.00 33.89  ? 44  HIS A O   1 
ATOM   148   C CB  . HIS A 1 24  ? 115.900 145.139 62.625  1.00 33.13  ? 44  HIS A CB  1 
ATOM   149   C CG  . HIS A 1 24  ? 115.459 145.731 61.328  1.00 34.52  ? 44  HIS A CG  1 
ATOM   150   N ND1 . HIS A 1 24  ? 115.929 145.314 60.101  1.00 35.36  ? 44  HIS A ND1 1 
ATOM   151   C CD2 . HIS A 1 24  ? 114.629 146.752 61.074  1.00 35.35  ? 44  HIS A CD2 1 
ATOM   152   C CE1 . HIS A 1 24  ? 115.379 146.052 59.145  1.00 35.88  ? 44  HIS A CE1 1 
ATOM   153   N NE2 . HIS A 1 24  ? 114.587 146.931 59.714  1.00 35.66  ? 44  HIS A NE2 1 
ATOM   154   N N   . HIS A 1 25  ? 115.716 145.372 65.677  1.00 35.50  ? 45  HIS A N   1 
ATOM   155   C CA  . HIS A 1 25  ? 115.802 144.821 67.018  1.00 37.48  ? 45  HIS A CA  1 
ATOM   156   C C   . HIS A 1 25  ? 116.093 143.326 66.949  1.00 38.13  ? 45  HIS A C   1 
ATOM   157   O O   . HIS A 1 25  ? 116.055 142.720 65.885  1.00 37.90  ? 45  HIS A O   1 
ATOM   158   C CB  . HIS A 1 25  ? 114.536 145.120 67.829  1.00 38.71  ? 45  HIS A CB  1 
ATOM   159   C CG  . HIS A 1 25  ? 114.629 146.359 68.653  1.00 39.72  ? 45  HIS A CG  1 
ATOM   160   N ND1 . HIS A 1 25  ? 114.363 147.623 68.177  1.00 40.31  ? 45  HIS A ND1 1 
ATOM   161   C CD2 . HIS A 1 25  ? 114.935 146.506 69.952  1.00 40.27  ? 45  HIS A CD2 1 
ATOM   162   C CE1 . HIS A 1 25  ? 114.517 148.500 69.159  1.00 41.00  ? 45  HIS A CE1 1 
ATOM   163   N NE2 . HIS A 1 25  ? 114.868 147.843 70.246  1.00 40.98  ? 45  HIS A NE2 1 
ATOM   164   N N   . GLN A 1 26  ? 116.393 142.747 68.112  1.00 40.04  ? 46  GLN A N   1 
ATOM   165   C CA  . GLN A 1 26  ? 116.645 141.324 68.223  1.00 41.83  ? 46  GLN A CA  1 
ATOM   166   C C   . GLN A 1 26  ? 115.355 140.572 67.912  1.00 44.79  ? 46  GLN A C   1 
ATOM   167   O O   . GLN A 1 26  ? 114.275 141.023 68.290  1.00 46.27  ? 46  GLN A O   1 
ATOM   168   C CB  . GLN A 1 26  ? 117.163 141.020 69.627  1.00 42.02  ? 46  GLN A CB  1 
ATOM   169   C CG  . GLN A 1 26  ? 117.688 139.607 69.809  1.00 42.10  ? 46  GLN A CG  1 
ATOM   170   C CD  . GLN A 1 26  ? 118.365 139.466 71.151  1.00 42.68  ? 46  GLN A CD  1 
ATOM   171   O OE1 . GLN A 1 26  ? 118.391 140.398 71.954  1.00 42.40  ? 46  GLN A OE1 1 
ATOM   172   N NE2 . GLN A 1 26  ? 118.932 138.297 71.403  1.00 43.11  ? 46  GLN A NE2 1 
ATOM   173   N N   . PRO A 1 27  ? 115.417 139.432 67.186  1.00 47.91  ? 47  PRO A N   1 
ATOM   174   C CA  . PRO A 1 27  ? 114.232 138.614 66.931  1.00 49.99  ? 47  PRO A CA  1 
ATOM   175   C C   . PRO A 1 27  ? 113.546 138.173 68.218  1.00 53.77  ? 47  PRO A C   1 
ATOM   176   O O   . PRO A 1 27  ? 114.209 137.903 69.218  1.00 53.89  ? 47  PRO A O   1 
ATOM   177   C CB  . PRO A 1 27  ? 114.777 137.399 66.167  1.00 49.62  ? 47  PRO A CB  1 
ATOM   178   C CG  . PRO A 1 27  ? 116.040 137.913 65.521  1.00 49.39  ? 47  PRO A CG  1 
ATOM   179   C CD  . PRO A 1 27  ? 116.615 138.890 66.528  1.00 48.74  ? 47  PRO A CD  1 
ATOM   180   N N   . THR A 1 28  ? 112.212 138.106 68.168  1.00 59.19  ? 48  THR A N   1 
ATOM   181   C CA  . THR A 1 28  ? 111.405 137.758 69.325  1.00 64.79  ? 48  THR A CA  1 
ATOM   182   C C   . THR A 1 28  ? 111.627 136.288 69.673  1.00 69.27  ? 48  THR A C   1 
ATOM   183   O O   . THR A 1 28  ? 111.998 135.489 68.816  1.00 70.11  ? 48  THR A O   1 
ATOM   184   C CB  . THR A 1 28  ? 109.919 138.051 69.074  1.00 66.49  ? 48  THR A CB  1 
ATOM   185   O OG1 . THR A 1 28  ? 109.748 139.442 68.795  1.00 66.17  ? 48  THR A OG1 1 
ATOM   186   C CG2 . THR A 1 28  ? 109.032 137.683 70.243  1.00 67.61  ? 48  THR A CG2 1 
ATOM   187   N N   . VAL A 1 29  ? 111.362 135.946 70.939  1.00 73.51  ? 49  VAL A N   1 
ATOM   188   C CA  . VAL A 1 29  ? 111.680 134.637 71.486  1.00 77.98  ? 49  VAL A CA  1 
ATOM   189   C C   . VAL A 1 29  ? 110.956 133.539 70.706  1.00 80.25  ? 49  VAL A C   1 
ATOM   190   O O   . VAL A 1 29  ? 111.425 132.403 70.680  1.00 79.74  ? 49  VAL A O   1 
ATOM   191   C CB  . VAL A 1 29  ? 111.347 134.573 72.990  1.00 80.77  ? 49  VAL A CB  1 
ATOM   192   C CG1 . VAL A 1 29  ? 109.855 134.407 73.247  1.00 81.49  ? 49  VAL A CG1 1 
ATOM   193   C CG2 . VAL A 1 29  ? 112.136 133.482 73.695  1.00 82.15  ? 49  VAL A CG2 1 
ATOM   194   N N   . ASP A 1 30  ? 109.815 133.873 70.089  1.00 83.18  ? 50  ASP A N   1 
ATOM   195   C CA  . ASP A 1 30  ? 109.032 132.885 69.365  1.00 86.39  ? 50  ASP A CA  1 
ATOM   196   C C   . ASP A 1 30  ? 109.449 132.820 67.897  1.00 87.23  ? 50  ASP A C   1 
ATOM   197   O O   . ASP A 1 30  ? 108.968 131.945 67.183  1.00 88.80  ? 50  ASP A O   1 
ATOM   198   C CB  . ASP A 1 30  ? 107.532 133.179 69.471  1.00 89.49  ? 50  ASP A CB  1 
ATOM   199   C CG  . ASP A 1 30  ? 107.111 134.487 68.825  1.00 91.45  ? 50  ASP A CG  1 
ATOM   200   O OD1 . ASP A 1 30  ? 107.666 135.527 69.218  1.00 91.48  ? 50  ASP A OD1 1 
ATOM   201   O OD2 . ASP A 1 30  ? 106.238 134.449 67.934  1.00 92.32  ? 50  ASP A OD2 1 
ATOM   202   N N   . LYS A 1 31  ? 110.272 133.768 67.428  1.00 86.86  ? 51  LYS A N   1 
ATOM   203   C CA  . LYS A 1 31  ? 110.549 133.906 66.006  1.00 87.62  ? 51  LYS A CA  1 
ATOM   204   C C   . LYS A 1 31  ? 112.055 133.898 65.752  1.00 84.85  ? 51  LYS A C   1 
ATOM   205   O O   . LYS A 1 31  ? 112.511 134.404 64.726  1.00 85.60  ? 51  LYS A O   1 
ATOM   206   C CB  . LYS A 1 31  ? 109.915 135.200 65.482  1.00 91.14  ? 51  LYS A CB  1 
ATOM   207   C CG  . LYS A 1 31  ? 109.271 135.093 64.107  1.00 94.95  ? 51  LYS A CG  1 
ATOM   208   C CD  . LYS A 1 31  ? 108.318 136.234 63.779  1.00 98.15  ? 51  LYS A CD  1 
ATOM   209   C CE  . LYS A 1 31  ? 107.186 136.427 64.770  1.00 99.88  ? 51  LYS A CE  1 
ATOM   210   N NZ  . LYS A 1 31  ? 106.353 135.210 64.933  1.00 100.40 ? 51  LYS A NZ  1 
ATOM   211   N N   . VAL A 1 32  ? 112.826 133.302 66.669  1.00 82.20  ? 52  VAL A N   1 
ATOM   212   C CA  . VAL A 1 32  ? 114.270 133.233 66.517  1.00 81.22  ? 52  VAL A CA  1 
ATOM   213   C C   . VAL A 1 32  ? 114.618 132.291 65.367  1.00 81.76  ? 52  VAL A C   1 
ATOM   214   O O   . VAL A 1 32  ? 115.532 132.578 64.605  1.00 82.44  ? 52  VAL A O   1 
ATOM   215   C CB  . VAL A 1 32  ? 114.973 132.816 67.823  1.00 81.74  ? 52  VAL A CB  1 
ATOM   216   C CG1 . VAL A 1 32  ? 114.745 133.843 68.920  1.00 81.55  ? 52  VAL A CG1 1 
ATOM   217   C CG2 . VAL A 1 32  ? 114.573 131.424 68.294  1.00 83.13  ? 52  VAL A CG2 1 
ATOM   218   N N   . HIS A 1 33  ? 113.879 131.182 65.238  1.00 82.45  ? 53  HIS A N   1 
ATOM   219   C CA  . HIS A 1 33  ? 114.183 130.155 64.253  1.00 83.15  ? 53  HIS A CA  1 
ATOM   220   C C   . HIS A 1 33  ? 113.963 130.683 62.836  1.00 83.97  ? 53  HIS A C   1 
ATOM   221   O O   . HIS A 1 33  ? 114.730 130.362 61.930  1.00 84.82  ? 53  HIS A O   1 
ATOM   222   C CB  . HIS A 1 33  ? 113.357 128.893 64.520  1.00 83.93  ? 53  HIS A CB  1 
ATOM   223   C CG  . HIS A 1 33  ? 113.562 128.351 65.892  1.00 84.96  ? 53  HIS A CG  1 
ATOM   224   N ND1 . HIS A 1 33  ? 114.801 127.967 66.356  1.00 84.54  ? 53  HIS A ND1 1 
ATOM   225   C CD2 . HIS A 1 33  ? 112.707 128.159 66.904  1.00 86.35  ? 53  HIS A CD2 1 
ATOM   226   C CE1 . HIS A 1 33  ? 114.684 127.545 67.606  1.00 84.89  ? 53  HIS A CE1 1 
ATOM   227   N NE2 . HIS A 1 33  ? 113.421 127.652 67.960  1.00 86.27  ? 53  HIS A NE2 1 
ATOM   228   N N   . GLU A 1 34  ? 112.917 131.495 62.653  1.00 85.47  ? 54  GLU A N   1 
ATOM   229   C CA  . GLU A 1 34  ? 112.625 132.090 61.358  1.00 87.77  ? 54  GLU A CA  1 
ATOM   230   C C   . GLU A 1 34  ? 113.727 133.085 60.991  1.00 83.90  ? 54  GLU A C   1 
ATOM   231   O O   . GLU A 1 34  ? 113.977 133.318 59.810  1.00 83.15  ? 54  GLU A O   1 
ATOM   232   C CB  . GLU A 1 34  ? 111.264 132.794 61.362  1.00 93.87  ? 54  GLU A CB  1 
ATOM   233   C CG  . GLU A 1 34  ? 110.101 131.904 61.766  1.00 98.18  ? 54  GLU A CG  1 
ATOM   234   C CD  . GLU A 1 34  ? 108.740 132.583 61.752  1.00 101.88 ? 54  GLU A CD  1 
ATOM   235   O OE1 . GLU A 1 34  ? 108.645 133.718 61.240  1.00 101.74 ? 54  GLU A OE1 1 
ATOM   236   O OE2 . GLU A 1 34  ? 107.776 131.978 62.264  1.00 103.57 ? 54  GLU A OE2 1 
ATOM   237   N N   . ARG A 1 35  ? 114.377 133.660 62.015  1.00 79.78  ? 55  ARG A N   1 
ATOM   238   C CA  . ARG A 1 35  ? 115.437 134.645 61.851  1.00 76.08  ? 55  ARG A CA  1 
ATOM   239   C C   . ARG A 1 35  ? 114.898 135.866 61.109  1.00 76.06  ? 55  ARG A C   1 
ATOM   240   O O   . ARG A 1 35  ? 115.487 136.311 60.124  1.00 77.41  ? 55  ARG A O   1 
ATOM   241   C CB  . ARG A 1 35  ? 116.665 134.044 61.154  1.00 73.59  ? 55  ARG A CB  1 
ATOM   242   C CG  . ARG A 1 35  ? 117.633 133.346 62.099  1.00 72.34  ? 55  ARG A CG  1 
ATOM   243   C CD  . ARG A 1 35  ? 118.808 132.706 61.386  1.00 71.99  ? 55  ARG A CD  1 
ATOM   244   N NE  . ARG A 1 35  ? 118.424 131.498 60.665  1.00 71.28  ? 55  ARG A NE  1 
ATOM   245   C CZ  . ARG A 1 35  ? 118.440 131.353 59.342  1.00 71.95  ? 55  ARG A CZ  1 
ATOM   246   N NH1 . ARG A 1 35  ? 118.780 132.358 58.554  1.00 71.03  ? 55  ARG A NH1 1 
ATOM   247   N NH2 . ARG A 1 35  ? 118.100 130.192 58.805  1.00 73.10  ? 55  ARG A NH2 1 
ATOM   248   N N   . LYS A 1 36  ? 113.774 136.405 61.600  1.00 75.17  ? 56  LYS A N   1 
ATOM   249   C CA  . LYS A 1 36  ? 113.312 137.721 61.188  1.00 75.83  ? 56  LYS A CA  1 
ATOM   250   C C   . LYS A 1 36  ? 113.334 138.631 62.413  1.00 70.53  ? 56  LYS A C   1 
ATOM   251   O O   . LYS A 1 36  ? 112.912 138.230 63.496  1.00 70.14  ? 56  LYS A O   1 
ATOM   252   C CB  . LYS A 1 36  ? 111.927 137.655 60.533  1.00 80.41  ? 56  LYS A CB  1 
ATOM   253   C CG  . LYS A 1 36  ? 110.728 137.703 61.474  1.00 84.55  ? 56  LYS A CG  1 
ATOM   254   C CD  . LYS A 1 36  ? 109.402 137.815 60.746  1.00 88.65  ? 56  LYS A CD  1 
ATOM   255   C CE  . LYS A 1 36  ? 109.253 139.102 59.961  1.00 90.96  ? 56  LYS A CE  1 
ATOM   256   N NZ  . LYS A 1 36  ? 107.902 139.227 59.366  1.00 91.93  ? 56  LYS A NZ  1 
ATOM   257   N N   . CYS A 1 37  ? 113.833 139.856 62.225  1.00 64.21  ? 57  CYS A N   1 
ATOM   258   C CA  . CYS A 1 37  ? 114.057 140.769 63.333  1.00 59.12  ? 57  CYS A CA  1 
ATOM   259   C C   . CYS A 1 37  ? 113.028 141.897 63.309  1.00 56.16  ? 57  CYS A C   1 
ATOM   260   O O   . CYS A 1 37  ? 112.466 142.217 62.264  1.00 55.61  ? 57  CYS A O   1 
ATOM   261   C CB  . CYS A 1 37  ? 115.486 141.299 63.320  1.00 58.04  ? 57  CYS A CB  1 
ATOM   262   S SG  . CYS A 1 37  ? 116.116 141.733 61.678  1.00 56.25  ? 57  CYS A SG  1 
ATOM   263   N N   . GLY A 1 38  ? 112.810 142.494 64.486  1.00 54.36  ? 58  GLY A N   1 
ATOM   264   C CA  . GLY A 1 38  ? 111.653 143.339 64.735  1.00 53.51  ? 58  GLY A CA  1 
ATOM   265   C C   . GLY A 1 38  ? 111.858 144.786 64.291  1.00 51.65  ? 58  GLY A C   1 
ATOM   266   O O   . GLY A 1 38  ? 112.247 145.045 63.154  1.00 51.12  ? 58  GLY A O   1 
ATOM   267   N N   . ALA A 1 39  ? 111.577 145.718 65.209  1.00 50.15  ? 59  ALA A N   1 
ATOM   268   C CA  . ALA A 1 39  ? 111.466 147.130 64.880  1.00 49.64  ? 59  ALA A CA  1 
ATOM   269   C C   . ALA A 1 39  ? 112.835 147.714 64.544  1.00 45.95  ? 59  ALA A C   1 
ATOM   270   O O   . ALA A 1 39  ? 113.854 147.246 65.045  1.00 45.22  ? 59  ALA A O   1 
ATOM   271   C CB  . ALA A 1 39  ? 110.826 147.870 66.032  1.00 51.31  ? 59  ALA A CB  1 
ATOM   272   N N   . VAL A 1 40  ? 112.827 148.752 63.701  1.00 42.64  ? 60  VAL A N   1 
ATOM   273   C CA  . VAL A 1 40  ? 114.035 149.456 63.301  1.00 40.48  ? 60  VAL A CA  1 
ATOM   274   C C   . VAL A 1 40  ? 114.520 150.322 64.462  1.00 38.31  ? 60  VAL A C   1 
ATOM   275   O O   . VAL A 1 40  ? 113.713 150.866 65.211  1.00 38.09  ? 60  VAL A O   1 
ATOM   276   C CB  . VAL A 1 40  ? 113.797 150.294 62.029  1.00 41.01  ? 60  VAL A CB  1 
ATOM   277   C CG1 . VAL A 1 40  ? 112.644 151.274 62.183  1.00 41.33  ? 60  VAL A CG1 1 
ATOM   278   C CG2 . VAL A 1 40  ? 115.053 151.031 61.589  1.00 41.20  ? 60  VAL A CG2 1 
ATOM   279   N N   . ARG A 1 41  ? 115.848 150.456 64.579  1.00 36.21  ? 61  ARG A N   1 
ATOM   280   C CA  . ARG A 1 41  ? 116.476 151.224 65.643  1.00 34.65  ? 61  ARG A CA  1 
ATOM   281   C C   . ARG A 1 41  ? 117.071 152.503 65.061  1.00 35.09  ? 61  ARG A C   1 
ATOM   282   O O   . ARG A 1 41  ? 117.570 152.501 63.937  1.00 34.85  ? 61  ARG A O   1 
ATOM   283   C CB  . ARG A 1 41  ? 117.570 150.394 66.319  1.00 33.14  ? 61  ARG A CB  1 
ATOM   284   C CG  . ARG A 1 41  ? 117.153 148.965 66.626  1.00 32.37  ? 61  ARG A CG  1 
ATOM   285   C CD  . ARG A 1 41  ? 118.240 148.174 67.322  1.00 31.66  ? 61  ARG A CD  1 
ATOM   286   N NE  . ARG A 1 41  ? 118.415 148.593 68.702  1.00 31.02  ? 61  ARG A NE  1 
ATOM   287   C CZ  . ARG A 1 41  ? 119.181 147.969 69.590  1.00 30.68  ? 61  ARG A CZ  1 
ATOM   288   N NH1 . ARG A 1 41  ? 119.916 146.932 69.229  1.00 30.88  ? 61  ARG A NH1 1 
ATOM   289   N NH2 . ARG A 1 41  ? 119.208 148.387 70.844  1.00 30.77  ? 61  ARG A NH2 1 
ATOM   290   N N   . GLU A 1 42  ? 117.038 153.586 65.849  1.00 35.92  ? 62  GLU A N   1 
ATOM   291   C CA  . GLU A 1 42  ? 117.553 154.873 65.411  1.00 36.58  ? 62  GLU A CA  1 
ATOM   292   C C   . GLU A 1 42  ? 118.993 155.051 65.883  1.00 35.50  ? 62  GLU A C   1 
ATOM   293   O O   . GLU A 1 42  ? 119.891 155.244 65.068  1.00 36.07  ? 62  GLU A O   1 
ATOM   294   C CB  . GLU A 1 42  ? 116.700 156.026 65.938  1.00 38.61  ? 62  GLU A CB  1 
ATOM   295   C CG  . GLU A 1 42  ? 117.265 157.384 65.561  1.00 40.42  ? 62  GLU A CG  1 
ATOM   296   C CD  . GLU A 1 42  ? 116.534 158.584 66.135  1.00 42.44  ? 62  GLU A CD  1 
ATOM   297   O OE1 . GLU A 1 42  ? 115.289 158.615 66.060  1.00 43.76  ? 62  GLU A OE1 1 
ATOM   298   O OE2 . GLU A 1 42  ? 117.217 159.482 66.670  1.00 43.62  ? 62  GLU A OE2 1 
ATOM   299   N N   . GLN A 1 43  ? 119.198 155.012 67.203  1.00 34.05  ? 63  GLN A N   1 
ATOM   300   C CA  . GLN A 1 43  ? 120.513 155.246 67.781  1.00 33.02  ? 63  GLN A CA  1 
ATOM   301   C C   . GLN A 1 43  ? 121.481 154.161 67.313  1.00 31.50  ? 63  GLN A C   1 
ATOM   302   O O   . GLN A 1 43  ? 122.579 154.469 66.865  1.00 31.77  ? 63  GLN A O   1 
ATOM   303   C CB  . GLN A 1 43  ? 120.438 155.297 69.310  1.00 34.03  ? 63  GLN A CB  1 
ATOM   304   C CG  . GLN A 1 43  ? 120.167 156.687 69.884  1.00 34.82  ? 63  GLN A CG  1 
ATOM   305   C CD  . GLN A 1 43  ? 118.894 157.330 69.387  1.00 35.32  ? 63  GLN A CD  1 
ATOM   306   O OE1 . GLN A 1 43  ? 117.794 156.820 69.595  1.00 35.79  ? 63  GLN A OE1 1 
ATOM   307   N NE2 . GLN A 1 43  ? 119.028 158.483 68.749  1.00 35.32  ? 63  GLN A NE2 1 
ATOM   308   N N   . TYR A 1 44  ? 121.047 152.901 67.395  1.00 30.36  ? 64  TYR A N   1 
ATOM   309   C CA  . TYR A 1 44  ? 121.888 151.762 67.073  1.00 29.36  ? 64  TYR A CA  1 
ATOM   310   C C   . TYR A 1 44  ? 121.836 151.400 65.595  1.00 28.53  ? 64  TYR A C   1 
ATOM   311   O O   . TYR A 1 44  ? 122.630 150.581 65.142  1.00 28.23  ? 64  TYR A O   1 
ATOM   312   C CB  . TYR A 1 44  ? 121.472 150.573 67.937  1.00 29.43  ? 64  TYR A CB  1 
ATOM   313   C CG  . TYR A 1 44  ? 122.218 150.520 69.239  1.00 29.81  ? 64  TYR A CG  1 
ATOM   314   C CD1 . TYR A 1 44  ? 122.894 151.631 69.714  1.00 30.31  ? 64  TYR A CD1 1 
ATOM   315   C CD2 . TYR A 1 44  ? 122.330 149.337 69.944  1.00 30.31  ? 64  TYR A CD2 1 
ATOM   316   C CE1 . TYR A 1 44  ? 123.633 151.573 70.881  1.00 30.86  ? 64  TYR A CE1 1 
ATOM   317   C CE2 . TYR A 1 44  ? 123.050 149.268 71.123  1.00 30.68  ? 64  TYR A CE2 1 
ATOM   318   C CZ  . TYR A 1 44  ? 123.710 150.387 71.586  1.00 30.84  ? 64  TYR A CZ  1 
ATOM   319   O OH  . TYR A 1 44  ? 124.437 150.330 72.742  1.00 31.43  ? 64  TYR A OH  1 
ATOM   320   N N   . GLY A 1 45  ? 120.904 151.994 64.854  1.00 28.74  ? 65  GLY A N   1 
ATOM   321   C CA  . GLY A 1 45  ? 120.666 151.584 63.482  1.00 29.22  ? 65  GLY A CA  1 
ATOM   322   C C   . GLY A 1 45  ? 121.018 152.691 62.497  1.00 29.54  ? 65  GLY A C   1 
ATOM   323   O O   . GLY A 1 45  ? 122.162 152.817 62.071  1.00 29.69  ? 65  GLY A O   1 
ATOM   324   N N   . ILE A 1 46  ? 120.020 153.513 62.183  1.00 30.39  ? 66  ILE A N   1 
ATOM   325   C CA  . ILE A 1 46  ? 120.114 154.461 61.089  1.00 31.44  ? 66  ILE A CA  1 
ATOM   326   C C   . ILE A 1 46  ? 121.241 155.454 61.352  1.00 32.00  ? 66  ILE A C   1 
ATOM   327   O O   . ILE A 1 46  ? 121.920 155.868 60.416  1.00 32.90  ? 66  ILE A O   1 
ATOM   328   C CB  . ILE A 1 46  ? 118.755 155.153 60.878  1.00 32.29  ? 66  ILE A CB  1 
ATOM   329   C CG1 . ILE A 1 46  ? 117.635 154.126 60.696  1.00 33.35  ? 66  ILE A CG1 1 
ATOM   330   C CG2 . ILE A 1 46  ? 118.807 156.136 59.719  1.00 32.53  ? 66  ILE A CG2 1 
ATOM   331   C CD1 . ILE A 1 46  ? 117.890 153.103 59.611  1.00 33.75  ? 66  ILE A CD1 1 
ATOM   332   N N   . GLN A 1 47  ? 121.453 155.828 62.619  1.00 31.62  ? 67  GLN A N   1 
ATOM   333   C CA  . GLN A 1 47  ? 122.470 156.818 62.928  1.00 31.29  ? 67  GLN A CA  1 
ATOM   334   C C   . GLN A 1 47  ? 123.848 156.274 62.565  1.00 30.16  ? 67  GLN A C   1 
ATOM   335   O O   . GLN A 1 47  ? 124.630 156.979 61.936  1.00 30.69  ? 67  GLN A O   1 
ATOM   336   C CB  . GLN A 1 47  ? 122.393 157.270 64.386  1.00 31.98  ? 67  GLN A CB  1 
ATOM   337   C CG  . GLN A 1 47  ? 121.241 158.234 64.639  1.00 33.01  ? 67  GLN A CG  1 
ATOM   338   C CD  . GLN A 1 47  ? 121.368 158.971 65.949  1.00 34.14  ? 67  GLN A CD  1 
ATOM   339   O OE1 . GLN A 1 47  ? 122.341 158.818 66.683  1.00 34.94  ? 67  GLN A OE1 1 
ATOM   340   N NE2 . GLN A 1 47  ? 120.382 159.802 66.243  1.00 35.11  ? 67  GLN A NE2 1 
ATOM   341   N N   . ARG A 1 48  ? 124.134 155.024 62.940  1.00 28.96  ? 68  ARG A N   1 
ATOM   342   C CA  . ARG A 1 48  ? 125.433 154.430 62.670  1.00 27.98  ? 68  ARG A CA  1 
ATOM   343   C C   . ARG A 1 48  ? 125.627 154.218 61.170  1.00 29.27  ? 68  ARG A C   1 
ATOM   344   O O   . ARG A 1 48  ? 126.719 154.443 60.660  1.00 30.27  ? 68  ARG A O   1 
ATOM   345   C CB  . ARG A 1 48  ? 125.595 153.121 63.443  1.00 26.08  ? 68  ARG A CB  1 
ATOM   346   C CG  . ARG A 1 48  ? 125.730 153.330 64.940  1.00 25.02  ? 68  ARG A CG  1 
ATOM   347   C CD  . ARG A 1 48  ? 125.845 152.024 65.685  1.00 24.43  ? 68  ARG A CD  1 
ATOM   348   N NE  . ARG A 1 48  ? 126.005 152.250 67.110  1.00 23.99  ? 68  ARG A NE  1 
ATOM   349   C CZ  . ARG A 1 48  ? 126.065 151.293 68.024  1.00 23.98  ? 68  ARG A CZ  1 
ATOM   350   N NH1 . ARG A 1 48  ? 125.851 150.033 67.690  1.00 24.01  ? 68  ARG A NH1 1 
ATOM   351   N NH2 . ARG A 1 48  ? 126.359 151.598 69.273  1.00 24.23  ? 68  ARG A NH2 1 
ATOM   352   N N   . VAL A 1 49  ? 124.570 153.794 60.470  1.00 30.17  ? 69  VAL A N   1 
ATOM   353   C CA  . VAL A 1 49  ? 124.649 153.568 59.036  1.00 31.14  ? 69  VAL A CA  1 
ATOM   354   C C   . VAL A 1 49  ? 124.957 154.886 58.328  1.00 32.87  ? 69  VAL A C   1 
ATOM   355   O O   . VAL A 1 49  ? 125.831 154.937 57.464  1.00 33.55  ? 69  VAL A O   1 
ATOM   356   C CB  . VAL A 1 49  ? 123.361 152.922 58.495  1.00 31.00  ? 69  VAL A CB  1 
ATOM   357   C CG1 . VAL A 1 49  ? 123.306 152.945 56.974  1.00 30.85  ? 69  VAL A CG1 1 
ATOM   358   C CG2 . VAL A 1 49  ? 123.199 151.502 59.017  1.00 31.23  ? 69  VAL A CG2 1 
ATOM   359   N N   . GLU A 1 50  ? 124.227 155.946 58.694  1.00 34.55  ? 70  GLU A N   1 
ATOM   360   C CA  . GLU A 1 50  ? 124.440 157.251 58.090  1.00 36.37  ? 70  GLU A CA  1 
ATOM   361   C C   . GLU A 1 50  ? 125.825 157.782 58.450  1.00 36.71  ? 70  GLU A C   1 
ATOM   362   O O   . GLU A 1 50  ? 126.462 158.439 57.630  1.00 37.25  ? 70  GLU A O   1 
ATOM   363   C CB  . GLU A 1 50  ? 123.357 158.248 58.513  1.00 37.89  ? 70  GLU A CB  1 
ATOM   364   C CG  . GLU A 1 50  ? 122.006 158.007 57.864  1.00 39.53  ? 70  GLU A CG  1 
ATOM   365   C CD  . GLU A 1 50  ? 122.005 157.758 56.366  1.00 40.98  ? 70  GLU A CD  1 
ATOM   366   O OE1 . GLU A 1 50  ? 121.016 157.191 55.888  1.00 41.83  ? 70  GLU A OE1 1 
ATOM   367   O OE2 . GLU A 1 50  ? 122.993 158.107 55.692  1.00 41.58  ? 70  GLU A OE2 1 
ATOM   368   N N   . ALA A 1 51  ? 126.282 157.492 59.673  1.00 36.58  ? 71  ALA A N   1 
ATOM   369   C CA  . ALA A 1 51  ? 127.587 157.940 60.129  1.00 36.55  ? 71  ALA A CA  1 
ATOM   370   C C   . ALA A 1 51  ? 128.681 157.326 59.262  1.00 37.94  ? 71  ALA A C   1 
ATOM   371   O O   . ALA A 1 51  ? 129.607 158.024 58.855  1.00 38.72  ? 71  ALA A O   1 
ATOM   372   C CB  . ALA A 1 51  ? 127.780 157.588 61.578  1.00 35.84  ? 71  ALA A CB  1 
ATOM   373   N N   . MET A 1 52  ? 128.561 156.020 58.988  1.00 39.38  ? 72  MET A N   1 
ATOM   374   C CA  . MET A 1 52  ? 129.531 155.318 58.162  1.00 40.55  ? 72  MET A CA  1 
ATOM   375   C C   . MET A 1 52  ? 129.488 155.882 56.743  1.00 41.98  ? 72  MET A C   1 
ATOM   376   O O   . MET A 1 52  ? 130.528 156.155 56.153  1.00 42.77  ? 72  MET A O   1 
ATOM   377   C CB  . MET A 1 52  ? 129.257 153.810 58.132  1.00 40.42  ? 72  MET A CB  1 
ATOM   378   C CG  . MET A 1 52  ? 129.930 153.086 56.980  1.00 41.12  ? 72  MET A CG  1 
ATOM   379   S SD  . MET A 1 52  ? 130.318 151.378 57.382  1.00 42.02  ? 72  MET A SD  1 
ATOM   380   C CE  . MET A 1 52  ? 131.927 151.199 56.608  1.00 42.78  ? 72  MET A CE  1 
ATOM   381   N N   . LEU A 1 53  ? 128.279 156.055 56.204  1.00 43.83  ? 73  LEU A N   1 
ATOM   382   C CA  . LEU A 1 53  ? 128.121 156.514 54.835  1.00 45.79  ? 73  LEU A CA  1 
ATOM   383   C C   . LEU A 1 53  ? 128.682 157.925 54.664  1.00 48.68  ? 73  LEU A C   1 
ATOM   384   O O   . LEU A 1 53  ? 129.128 158.277 53.575  1.00 50.05  ? 73  LEU A O   1 
ATOM   385   C CB  . LEU A 1 53  ? 126.639 156.444 54.451  1.00 45.50  ? 73  LEU A CB  1 
ATOM   386   C CG  . LEU A 1 53  ? 126.139 155.047 54.080  1.00 45.37  ? 73  LEU A CG  1 
ATOM   387   C CD1 . LEU A 1 53  ? 124.625 155.015 53.957  1.00 45.60  ? 73  LEU A CD1 1 
ATOM   388   C CD2 . LEU A 1 53  ? 126.776 154.577 52.778  1.00 45.54  ? 73  LEU A CD2 1 
ATOM   389   N N   . HIS A 1 54  ? 128.650 158.736 55.728  1.00 51.00  ? 74  HIS A N   1 
ATOM   390   C CA  . HIS A 1 54  ? 129.138 160.102 55.637  1.00 53.49  ? 74  HIS A CA  1 
ATOM   391   C C   . HIS A 1 54  ? 130.639 160.167 55.898  1.00 53.95  ? 74  HIS A C   1 
ATOM   392   O O   . HIS A 1 54  ? 131.337 160.966 55.277  1.00 55.85  ? 74  HIS A O   1 
ATOM   393   C CB  . HIS A 1 54  ? 128.404 161.034 56.603  1.00 56.11  ? 74  HIS A CB  1 
ATOM   394   C CG  . HIS A 1 54  ? 128.750 162.467 56.380  1.00 58.87  ? 74  HIS A CG  1 
ATOM   395   N ND1 . HIS A 1 54  ? 129.322 163.263 57.347  1.00 60.79  ? 74  HIS A ND1 1 
ATOM   396   C CD2 . HIS A 1 54  ? 128.585 163.251 55.303  1.00 60.41  ? 74  HIS A CD2 1 
ATOM   397   C CE1 . HIS A 1 54  ? 129.495 164.484 56.861  1.00 62.45  ? 74  HIS A CE1 1 
ATOM   398   N NE2 . HIS A 1 54  ? 129.055 164.499 55.621  1.00 61.94  ? 74  HIS A NE2 1 
ATOM   399   N N   . THR A 1 55  ? 131.135 159.349 56.834  1.00 52.90  ? 75  THR A N   1 
ATOM   400   C CA  . THR A 1 55  ? 132.551 159.383 57.162  1.00 52.57  ? 75  THR A CA  1 
ATOM   401   C C   . THR A 1 55  ? 133.369 158.842 55.991  1.00 54.25  ? 75  THR A C   1 
ATOM   402   O O   . THR A 1 55  ? 134.482 159.300 55.768  1.00 55.74  ? 75  THR A O   1 
ATOM   403   C CB  . THR A 1 55  ? 132.863 158.655 58.472  1.00 50.96  ? 75  THR A CB  1 
ATOM   404   O OG1 . THR A 1 55  ? 134.190 159.014 58.867  1.00 50.76  ? 75  THR A OG1 1 
ATOM   405   C CG2 . THR A 1 55  ? 132.750 157.156 58.344  1.00 50.62  ? 75  THR A CG2 1 
ATOM   406   N N   . LEU A 1 56  ? 132.819 157.878 55.242  1.00 56.71  ? 76  LEU A N   1 
ATOM   407   C CA  . LEU A 1 56  ? 133.470 157.383 54.037  1.00 59.11  ? 76  LEU A CA  1 
ATOM   408   C C   . LEU A 1 56  ? 133.629 158.512 53.019  1.00 63.55  ? 76  LEU A C   1 
ATOM   409   O O   . LEU A 1 56  ? 134.681 158.644 52.405  1.00 65.44  ? 76  LEU A O   1 
ATOM   410   C CB  . LEU A 1 56  ? 132.658 156.229 53.439  1.00 58.27  ? 76  LEU A CB  1 
ATOM   411   C CG  . LEU A 1 56  ? 133.086 154.823 53.853  1.00 57.99  ? 76  LEU A CG  1 
ATOM   412   C CD1 . LEU A 1 56  ? 134.473 154.507 53.328  1.00 58.84  ? 76  LEU A CD1 1 
ATOM   413   C CD2 . LEU A 1 56  ? 133.059 154.652 55.357  1.00 57.36  ? 76  LEU A CD2 1 
ATOM   414   N N   . GLU A 1 57  ? 132.575 159.315 52.841  1.00 67.78  ? 77  GLU A N   1 
ATOM   415   C CA  . GLU A 1 57  ? 132.587 160.421 51.898  1.00 71.90  ? 77  GLU A CA  1 
ATOM   416   C C   . GLU A 1 57  ? 133.569 161.491 52.371  1.00 70.41  ? 77  GLU A C   1 
ATOM   417   O O   . GLU A 1 57  ? 134.241 162.117 51.555  1.00 71.08  ? 77  GLU A O   1 
ATOM   418   C CB  . GLU A 1 57  ? 131.173 160.994 51.783  1.00 77.80  ? 77  GLU A CB  1 
ATOM   419   C CG  . GLU A 1 57  ? 130.843 161.622 50.441  1.00 83.44  ? 77  GLU A CG  1 
ATOM   420   C CD  . GLU A 1 57  ? 129.398 162.084 50.354  1.00 88.84  ? 77  GLU A CD  1 
ATOM   421   O OE1 . GLU A 1 57  ? 128.533 161.367 50.902  1.00 90.88  ? 77  GLU A OE1 1 
ATOM   422   O OE2 . GLU A 1 57  ? 129.137 163.143 49.735  1.00 90.54  ? 77  GLU A OE2 1 
ATOM   423   N N   . ARG A 1 58  ? 133.639 161.692 53.695  1.00 69.80  ? 78  ARG A N   1 
ATOM   424   C CA  . ARG A 1 58  ? 134.572 162.644 54.281  1.00 71.47  ? 78  ARG A CA  1 
ATOM   425   C C   . ARG A 1 58  ? 136.011 162.210 54.000  1.00 71.80  ? 78  ARG A C   1 
ATOM   426   O O   . ARG A 1 58  ? 136.851 163.048 53.684  1.00 73.63  ? 78  ARG A O   1 
ATOM   427   C CB  . ARG A 1 58  ? 134.342 162.806 55.788  1.00 73.05  ? 78  ARG A CB  1 
ATOM   428   C CG  . ARG A 1 58  ? 133.653 164.103 56.187  1.00 75.60  ? 78  ARG A CG  1 
ATOM   429   C CD  . ARG A 1 58  ? 133.566 164.269 57.693  1.00 77.19  ? 78  ARG A CD  1 
ATOM   430   N NE  . ARG A 1 58  ? 134.873 164.353 58.333  1.00 79.09  ? 78  ARG A NE  1 
ATOM   431   C CZ  . ARG A 1 58  ? 135.463 165.484 58.704  1.00 82.09  ? 78  ARG A CZ  1 
ATOM   432   N NH1 . ARG A 1 58  ? 134.933 166.650 58.374  1.00 82.50  ? 78  ARG A NH1 1 
ATOM   433   N NH2 . ARG A 1 58  ? 136.602 165.448 59.376  1.00 83.31  ? 78  ARG A NH2 1 
ATOM   434   N N   . ILE A 1 59  ? 136.286 160.906 54.133  1.00 70.46  ? 79  ILE A N   1 
ATOM   435   C CA  . ILE A 1 59  ? 137.603 160.353 53.853  1.00 68.51  ? 79  ILE A CA  1 
ATOM   436   C C   . ILE A 1 59  ? 137.938 160.546 52.376  1.00 71.42  ? 79  ILE A C   1 
ATOM   437   O O   . ILE A 1 59  ? 139.055 160.941 52.043  1.00 71.89  ? 79  ILE A O   1 
ATOM   438   C CB  . ILE A 1 59  ? 137.680 158.869 54.269  1.00 64.79  ? 79  ILE A CB  1 
ATOM   439   C CG1 . ILE A 1 59  ? 137.829 158.732 55.783  1.00 63.16  ? 79  ILE A CG1 1 
ATOM   440   C CG2 . ILE A 1 59  ? 138.803 158.148 53.539  1.00 64.32  ? 79  ILE A CG2 1 
ATOM   441   C CD1 . ILE A 1 59  ? 137.507 157.364 56.324  1.00 63.48  ? 79  ILE A CD1 1 
ATOM   442   N N   . ASN A 1 60  ? 136.964 160.256 51.505  1.00 75.76  ? 80  ASN A N   1 
ATOM   443   C CA  . ASN A 1 60  ? 137.169 160.340 50.068  1.00 80.29  ? 80  ASN A CA  1 
ATOM   444   C C   . ASN A 1 60  ? 137.493 161.777 49.665  1.00 84.69  ? 80  ASN A C   1 
ATOM   445   O O   . ASN A 1 60  ? 138.367 161.999 48.828  1.00 85.88  ? 80  ASN A O   1 
ATOM   446   C CB  . ASN A 1 60  ? 135.961 159.802 49.298  1.00 80.12  ? 80  ASN A CB  1 
ATOM   447   C CG  . ASN A 1 60  ? 135.773 158.310 49.479  1.00 79.83  ? 80  ASN A CG  1 
ATOM   448   O OD1 . ASN A 1 60  ? 136.554 157.657 50.170  1.00 78.62  ? 80  ASN A OD1 1 
ATOM   449   N ND2 . ASN A 1 60  ? 134.737 157.757 48.869  1.00 80.10  ? 80  ASN A ND2 1 
ATOM   450   N N   . SER A 1 61  ? 136.784 162.745 50.261  1.00 89.83  ? 81  SER A N   1 
ATOM   451   C CA  . SER A 1 61  ? 136.999 164.152 49.961  1.00 95.13  ? 81  SER A CA  1 
ATOM   452   C C   . SER A 1 61  ? 138.357 164.616 50.488  1.00 99.11  ? 81  SER A C   1 
ATOM   453   O O   . SER A 1 61  ? 139.009 165.444 49.855  1.00 100.06 ? 81  SER A O   1 
ATOM   454   C CB  . SER A 1 61  ? 135.884 165.006 50.514  1.00 96.37  ? 81  SER A CB  1 
ATOM   455   O OG  . SER A 1 61  ? 134.637 164.665 49.925  1.00 96.70  ? 81  SER A OG  1 
ATOM   456   N N   . ASP A 1 62  ? 138.774 164.081 51.644  1.00 102.61 ? 82  ASP A N   1 
ATOM   457   C CA  . ASP A 1 62  ? 140.005 164.510 52.288  1.00 106.65 ? 82  ASP A CA  1 
ATOM   458   C C   . ASP A 1 62  ? 141.196 163.952 51.510  1.00 107.66 ? 82  ASP A C   1 
ATOM   459   O O   . ASP A 1 62  ? 141.353 162.736 51.412  1.00 107.09 ? 82  ASP A O   1 
ATOM   460   C CB  . ASP A 1 62  ? 140.043 164.079 53.757  1.00 109.60 ? 82  ASP A CB  1 
ATOM   461   C CG  . ASP A 1 62  ? 141.005 164.882 54.617  1.00 112.20 ? 82  ASP A CG  1 
ATOM   462   O OD1 . ASP A 1 62  ? 141.601 165.844 54.092  1.00 112.20 ? 82  ASP A OD1 1 
ATOM   463   O OD2 . ASP A 1 62  ? 141.146 164.542 55.809  1.00 114.31 ? 82  ASP A OD2 1 
ATOM   464   N N   . PRO A 1 63  ? 142.072 164.807 50.929  1.00 110.18 ? 83  PRO A N   1 
ATOM   465   C CA  . PRO A 1 63  ? 143.197 164.325 50.128  1.00 109.83 ? 83  PRO A CA  1 
ATOM   466   C C   . PRO A 1 63  ? 144.391 163.835 50.946  1.00 106.79 ? 83  PRO A C   1 
ATOM   467   O O   . PRO A 1 63  ? 145.226 163.096 50.431  1.00 104.17 ? 83  PRO A O   1 
ATOM   468   C CB  . PRO A 1 63  ? 143.622 165.539 49.281  1.00 112.37 ? 83  PRO A CB  1 
ATOM   469   C CG  . PRO A 1 63  ? 142.718 166.694 49.703  1.00 112.49 ? 83  PRO A CG  1 
ATOM   470   C CD  . PRO A 1 63  ? 142.031 166.276 50.987  1.00 111.82 ? 83  PRO A CD  1 
ATOM   471   N N   . THR A 1 64  ? 144.470 164.254 52.217  1.00 106.84 ? 84  THR A N   1 
ATOM   472   C CA  . THR A 1 64  ? 145.610 163.938 53.064  1.00 107.65 ? 84  THR A CA  1 
ATOM   473   C C   . THR A 1 64  ? 145.570 162.480 53.517  1.00 106.47 ? 84  THR A C   1 
ATOM   474   O O   . THR A 1 64  ? 146.592 161.957 53.955  1.00 106.95 ? 84  THR A O   1 
ATOM   475   C CB  . THR A 1 64  ? 145.683 164.860 54.289  1.00 109.84 ? 84  THR A CB  1 
ATOM   476   O OG1 . THR A 1 64  ? 146.958 164.665 54.902  1.00 110.13 ? 84  THR A OG1 1 
ATOM   477   C CG2 . THR A 1 64  ? 144.588 164.603 55.303  1.00 110.18 ? 84  THR A CG2 1 
ATOM   478   N N   . LEU A 1 65  ? 144.390 161.845 53.448  1.00 103.39 ? 85  LEU A N   1 
ATOM   479   C CA  . LEU A 1 65  ? 144.240 160.460 53.872  1.00 99.77  ? 85  LEU A CA  1 
ATOM   480   C C   . LEU A 1 65  ? 143.716 159.616 52.715  1.00 97.65  ? 85  LEU A C   1 
ATOM   481   O O   . LEU A 1 65  ? 142.712 159.968 52.099  1.00 98.26  ? 85  LEU A O   1 
ATOM   482   C CB  . LEU A 1 65  ? 143.272 160.386 55.054  1.00 97.54  ? 85  LEU A CB  1 
ATOM   483   C CG  . LEU A 1 65  ? 143.217 159.016 55.725  1.00 94.29  ? 85  LEU A CG  1 
ATOM   484   C CD1 . LEU A 1 65  ? 144.352 158.885 56.728  1.00 91.89  ? 85  LEU A CD1 1 
ATOM   485   C CD2 . LEU A 1 65  ? 141.871 158.778 56.395  1.00 93.69  ? 85  LEU A CD2 1 
ATOM   486   N N   . LEU A 1 66  ? 144.390 158.483 52.471  1.00 95.91  ? 86  LEU A N   1 
ATOM   487   C CA  . LEU A 1 66  ? 144.086 157.578 51.370  1.00 96.76  ? 86  LEU A CA  1 
ATOM   488   C C   . LEU A 1 66  ? 143.908 158.353 50.067  1.00 100.08 ? 86  LEU A C   1 
ATOM   489   O O   . LEU A 1 66  ? 142.808 158.409 49.519  1.00 100.27 ? 86  LEU A O   1 
ATOM   490   C CB  . LEU A 1 66  ? 142.829 156.762 51.692  1.00 95.71  ? 86  LEU A CB  1 
ATOM   491   C CG  . LEU A 1 66  ? 143.062 155.363 52.261  1.00 94.14  ? 86  LEU A CG  1 
ATOM   492   C CD1 . LEU A 1 66  ? 141.740 154.627 52.411  1.00 93.53  ? 86  LEU A CD1 1 
ATOM   493   C CD2 . LEU A 1 66  ? 144.014 154.550 51.392  1.00 94.09  ? 86  LEU A CD2 1 
ATOM   494   N N   . PRO A 1 67  ? 144.983 158.959 49.519  1.00 105.52 ? 87  PRO A N   1 
ATOM   495   C CA  . PRO A 1 67  ? 144.859 159.818 48.343  1.00 109.27 ? 87  PRO A CA  1 
ATOM   496   C C   . PRO A 1 67  ? 144.641 159.027 47.056  1.00 111.27 ? 87  PRO A C   1 
ATOM   497   O O   . PRO A 1 67  ? 145.187 157.936 46.895  1.00 108.64 ? 87  PRO A O   1 
ATOM   498   C CB  . PRO A 1 67  ? 146.202 160.564 48.314  1.00 109.33 ? 87  PRO A CB  1 
ATOM   499   C CG  . PRO A 1 67  ? 147.176 159.596 48.954  1.00 108.01 ? 87  PRO A CG  1 
ATOM   500   C CD  . PRO A 1 67  ? 146.371 158.839 49.988  1.00 106.30 ? 87  PRO A CD  1 
ATOM   501   N N   . ASN A 1 68  ? 143.791 159.586 46.181  1.00 115.71 ? 88  ASN A N   1 
ATOM   502   C CA  . ASN A 1 68  ? 143.647 159.174 44.789  1.00 119.48 ? 88  ASN A CA  1 
ATOM   503   C C   . ASN A 1 68  ? 142.889 157.853 44.641  1.00 114.56 ? 88  ASN A C   1 
ATOM   504   O O   . ASN A 1 68  ? 142.739 157.365 43.522  1.00 113.40 ? 88  ASN A O   1 
ATOM   505   C CB  . ASN A 1 68  ? 144.997 159.111 44.061  1.00 126.00 ? 88  ASN A CB  1 
ATOM   506   C CG  . ASN A 1 68  ? 145.169 160.221 43.043  1.00 130.46 ? 88  ASN A CG  1 
ATOM   507   O OD1 . ASN A 1 68  ? 144.319 160.394 42.172  1.00 130.71 ? 88  ASN A OD1 1 
ATOM   508   N ND2 . ASN A 1 68  ? 146.256 160.973 43.137  1.00 131.82 ? 88  ASN A ND2 1 
ATOM   509   N N   . ILE A 1 69  ? 142.414 157.272 45.753  1.00 110.25 ? 89  ILE A N   1 
ATOM   510   C CA  . ILE A 1 69  ? 141.611 156.059 45.696  1.00 106.53 ? 89  ILE A CA  1 
ATOM   511   C C   . ILE A 1 69  ? 140.377 156.245 46.574  1.00 101.47 ? 89  ILE A C   1 
ATOM   512   O O   . ILE A 1 69  ? 140.457 156.844 47.644  1.00 102.21 ? 89  ILE A O   1 
ATOM   513   C CB  . ILE A 1 69  ? 142.417 154.802 46.092  1.00 106.65 ? 89  ILE A CB  1 
ATOM   514   C CG1 . ILE A 1 69  ? 142.768 154.746 47.583  1.00 105.22 ? 89  ILE A CG1 1 
ATOM   515   C CG2 . ILE A 1 69  ? 143.659 154.660 45.225  1.00 108.47 ? 89  ILE A CG2 1 
ATOM   516   C CD1 . ILE A 1 69  ? 143.301 153.400 48.025  1.00 105.27 ? 89  ILE A CD1 1 
ATOM   517   N N   . THR A 1 70  ? 139.249 155.701 46.107  1.00 95.13  ? 90  THR A N   1 
ATOM   518   C CA  . THR A 1 70  ? 137.989 155.798 46.822  1.00 90.17  ? 90  THR A CA  1 
ATOM   519   C C   . THR A 1 70  ? 137.814 154.575 47.718  1.00 84.06  ? 90  THR A C   1 
ATOM   520   O O   . THR A 1 70  ? 138.365 153.506 47.452  1.00 84.75  ? 90  THR A O   1 
ATOM   521   C CB  . THR A 1 70  ? 136.814 155.942 45.847  1.00 91.03  ? 90  THR A CB  1 
ATOM   522   O OG1 . THR A 1 70  ? 136.780 154.783 45.016  1.00 90.40  ? 90  THR A OG1 1 
ATOM   523   C CG2 . THR A 1 70  ? 136.915 157.185 44.990  1.00 92.15  ? 90  THR A CG2 1 
ATOM   524   N N   . LEU A 1 71  ? 137.031 154.764 48.783  1.00 76.24  ? 91  LEU A N   1 
ATOM   525   C CA  . LEU A 1 71  ? 136.761 153.722 49.759  1.00 70.20  ? 91  LEU A CA  1 
ATOM   526   C C   . LEU A 1 71  ? 135.256 153.473 49.780  1.00 67.67  ? 91  LEU A C   1 
ATOM   527   O O   . LEU A 1 71  ? 134.488 154.357 50.162  1.00 68.74  ? 91  LEU A O   1 
ATOM   528   C CB  . LEU A 1 71  ? 137.289 154.185 51.124  1.00 68.80  ? 91  LEU A CB  1 
ATOM   529   C CG  . LEU A 1 71  ? 137.678 153.079 52.104  1.00 68.55  ? 91  LEU A CG  1 
ATOM   530   C CD1 . LEU A 1 71  ? 138.867 152.283 51.588  1.00 69.11  ? 91  LEU A CD1 1 
ATOM   531   C CD2 . LEU A 1 71  ? 137.997 153.658 53.477  1.00 67.83  ? 91  LEU A CD2 1 
ATOM   532   N N   . GLY A 1 72  ? 134.851 152.285 49.317  1.00 64.03  ? 92  GLY A N   1 
ATOM   533   C CA  . GLY A 1 72  ? 133.447 151.901 49.285  1.00 61.07  ? 92  GLY A CA  1 
ATOM   534   C C   . GLY A 1 72  ? 133.077 151.070 50.509  1.00 57.79  ? 92  GLY A C   1 
ATOM   535   O O   . GLY A 1 72  ? 133.959 150.599 51.225  1.00 56.85  ? 92  GLY A O   1 
ATOM   536   N N   . CYS A 1 73  ? 131.774 150.867 50.730  1.00 55.59  ? 93  CYS A N   1 
ATOM   537   C CA  . CYS A 1 73  ? 131.321 150.156 51.914  1.00 53.76  ? 93  CYS A CA  1 
ATOM   538   C C   . CYS A 1 73  ? 130.102 149.293 51.598  1.00 51.00  ? 93  CYS A C   1 
ATOM   539   O O   . CYS A 1 73  ? 129.370 149.541 50.639  1.00 51.63  ? 93  CYS A O   1 
ATOM   540   C CB  . CYS A 1 73  ? 131.000 151.115 53.055  1.00 54.77  ? 93  CYS A CB  1 
ATOM   541   S SG  . CYS A 1 73  ? 129.742 152.352 52.641  1.00 57.82  ? 93  CYS A SG  1 
ATOM   542   N N   . GLU A 1 74  ? 129.935 148.264 52.435  1.00 48.30  ? 94  GLU A N   1 
ATOM   543   C CA  . GLU A 1 74  ? 128.847 147.309 52.345  1.00 46.21  ? 94  GLU A CA  1 
ATOM   544   C C   . GLU A 1 74  ? 128.304 147.090 53.755  1.00 43.25  ? 94  GLU A C   1 
ATOM   545   O O   . GLU A 1 74  ? 128.898 146.369 54.557  1.00 42.96  ? 94  GLU A O   1 
ATOM   546   C CB  . GLU A 1 74  ? 129.329 146.010 51.700  1.00 47.37  ? 94  GLU A CB  1 
ATOM   547   C CG  . GLU A 1 74  ? 128.222 144.985 51.540  1.00 49.07  ? 94  GLU A CG  1 
ATOM   548   C CD  . GLU A 1 74  ? 128.570 143.784 50.678  1.00 51.00  ? 94  GLU A CD  1 
ATOM   549   O OE1 . GLU A 1 74  ? 129.547 143.865 49.905  1.00 51.77  ? 94  GLU A OE1 1 
ATOM   550   O OE2 . GLU A 1 74  ? 127.857 142.766 50.776  1.00 51.45  ? 94  GLU A OE2 1 
ATOM   551   N N   . ILE A 1 75  ? 127.169 147.735 54.044  1.00 40.36  ? 95  ILE A N   1 
ATOM   552   C CA  . ILE A 1 75  ? 126.565 147.682 55.362  1.00 37.99  ? 95  ILE A CA  1 
ATOM   553   C C   . ILE A 1 75  ? 125.463 146.631 55.356  1.00 36.63  ? 95  ILE A C   1 
ATOM   554   O O   . ILE A 1 75  ? 124.620 146.607 54.463  1.00 37.44  ? 95  ILE A O   1 
ATOM   555   C CB  . ILE A 1 75  ? 126.038 149.070 55.775  1.00 37.28  ? 95  ILE A CB  1 
ATOM   556   C CG1 . ILE A 1 75  ? 127.156 150.115 55.819  1.00 37.01  ? 95  ILE A CG1 1 
ATOM   557   C CG2 . ILE A 1 75  ? 125.285 149.007 57.091  1.00 36.94  ? 95  ILE A CG2 1 
ATOM   558   C CD1 . ILE A 1 75  ? 127.164 151.054 54.641  1.00 37.12  ? 95  ILE A CD1 1 
ATOM   559   N N   . ARG A 1 76  ? 125.488 145.773 56.380  1.00 35.84  ? 96  ARG A N   1 
ATOM   560   C CA  . ARG A 1 76  ? 124.478 144.748 56.561  1.00 35.61  ? 96  ARG A CA  1 
ATOM   561   C C   . ARG A 1 76  ? 123.907 144.848 57.971  1.00 34.73  ? 96  ARG A C   1 
ATOM   562   O O   . ARG A 1 76  ? 124.477 145.490 58.853  1.00 34.67  ? 96  ARG A O   1 
ATOM   563   C CB  . ARG A 1 76  ? 125.069 143.359 56.309  1.00 36.34  ? 96  ARG A CB  1 
ATOM   564   C CG  . ARG A 1 76  ? 125.525 143.143 54.877  1.00 37.39  ? 96  ARG A CG  1 
ATOM   565   C CD  . ARG A 1 76  ? 125.897 141.706 54.588  1.00 38.21  ? 96  ARG A CD  1 
ATOM   566   N NE  . ARG A 1 76  ? 126.148 141.541 53.166  1.00 39.25  ? 96  ARG A NE  1 
ATOM   567   C CZ  . ARG A 1 76  ? 125.283 141.048 52.285  1.00 40.67  ? 96  ARG A CZ  1 
ATOM   568   N NH1 . ARG A 1 76  ? 124.095 140.612 52.669  1.00 40.85  ? 96  ARG A NH1 1 
ATOM   569   N NH2 . ARG A 1 76  ? 125.617 140.983 51.007  1.00 41.09  ? 96  ARG A NH2 1 
ATOM   570   N N   . ASP A 1 77  ? 122.765 144.186 58.157  1.00 33.69  ? 97  ASP A N   1 
ATOM   571   C CA  . ASP A 1 77  ? 122.014 144.253 59.393  1.00 33.18  ? 97  ASP A CA  1 
ATOM   572   C C   . ASP A 1 77  ? 122.209 142.946 60.152  1.00 32.48  ? 97  ASP A C   1 
ATOM   573   O O   . ASP A 1 77  ? 121.887 141.881 59.635  1.00 32.82  ? 97  ASP A O   1 
ATOM   574   C CB  . ASP A 1 77  ? 120.545 144.535 59.082  1.00 33.71  ? 97  ASP A CB  1 
ATOM   575   C CG  . ASP A 1 77  ? 119.594 144.321 60.241  1.00 33.81  ? 97  ASP A CG  1 
ATOM   576   O OD1 . ASP A 1 77  ? 120.054 144.295 61.389  1.00 33.83  ? 97  ASP A OD1 1 
ATOM   577   O OD2 . ASP A 1 77  ? 118.406 144.104 59.954  1.00 33.91  ? 97  ASP A OD2 1 
ATOM   578   N N   . SER A 1 78  ? 122.687 143.053 61.395  1.00 31.59  ? 98  SER A N   1 
ATOM   579   C CA  . SER A 1 78  ? 122.907 141.890 62.238  1.00 30.93  ? 98  SER A CA  1 
ATOM   580   C C   . SER A 1 78  ? 121.710 141.637 63.154  1.00 31.64  ? 98  SER A C   1 
ATOM   581   O O   . SER A 1 78  ? 121.641 140.591 63.789  1.00 32.21  ? 98  SER A O   1 
ATOM   582   C CB  . SER A 1 78  ? 124.175 142.041 63.033  1.00 30.42  ? 98  SER A CB  1 
ATOM   583   O OG  . SER A 1 78  ? 124.097 143.154 63.909  1.00 30.17  ? 98  SER A OG  1 
ATOM   584   N N   . CYS A 1 79  ? 120.784 142.600 63.245  1.00 32.25  ? 99  CYS A N   1 
ATOM   585   C CA  . CYS A 1 79  ? 119.610 142.502 64.102  1.00 33.26  ? 99  CYS A CA  1 
ATOM   586   C C   . CYS A 1 79  ? 119.994 142.132 65.534  1.00 31.25  ? 99  CYS A C   1 
ATOM   587   O O   . CYS A 1 79  ? 119.170 141.588 66.264  1.00 31.96  ? 99  CYS A O   1 
ATOM   588   C CB  . CYS A 1 79  ? 118.605 141.479 63.582  1.00 36.77  ? 99  CYS A CB  1 
ATOM   589   S SG  . CYS A 1 79  ? 118.162 141.700 61.839  1.00 43.77  ? 99  CYS A SG  1 
ATOM   590   N N   . TRP A 1 80  ? 121.236 142.432 65.933  1.00 29.47  ? 100 TRP A N   1 
ATOM   591   C CA  . TRP A 1 80  ? 121.728 142.144 67.272  1.00 28.44  ? 100 TRP A CA  1 
ATOM   592   C C   . TRP A 1 80  ? 121.551 140.667 67.616  1.00 27.72  ? 100 TRP A C   1 
ATOM   593   O O   . TRP A 1 80  ? 121.253 140.318 68.755  1.00 27.45  ? 100 TRP A O   1 
ATOM   594   C CB  . TRP A 1 80  ? 121.034 143.046 68.299  1.00 28.43  ? 100 TRP A CB  1 
ATOM   595   C CG  . TRP A 1 80  ? 121.805 143.200 69.573  1.00 28.78  ? 100 TRP A CG  1 
ATOM   596   C CD1 . TRP A 1 80  ? 121.802 142.377 70.662  1.00 29.23  ? 100 TRP A CD1 1 
ATOM   597   C CD2 . TRP A 1 80  ? 122.749 144.241 69.865  1.00 28.65  ? 100 TRP A CD2 1 
ATOM   598   N NE1 . TRP A 1 80  ? 122.664 142.845 71.616  1.00 29.05  ? 100 TRP A NE1 1 
ATOM   599   C CE2 . TRP A 1 80  ? 123.262 143.987 71.154  1.00 28.81  ? 100 TRP A CE2 1 
ATOM   600   C CE3 . TRP A 1 80  ? 123.205 145.358 69.161  1.00 28.62  ? 100 TRP A CE3 1 
ATOM   601   C CZ2 . TRP A 1 80  ? 124.192 144.827 71.760  1.00 29.12  ? 100 TRP A CZ2 1 
ATOM   602   C CZ3 . TRP A 1 80  ? 124.132 146.182 69.755  1.00 29.00  ? 100 TRP A CZ3 1 
ATOM   603   C CH2 . TRP A 1 80  ? 124.623 145.914 71.034  1.00 29.33  ? 100 TRP A CH2 1 
ATOM   604   N N   . HIS A 1 81  ? 121.756 139.798 66.625  1.00 27.67  ? 101 HIS A N   1 
ATOM   605   C CA  . HIS A 1 81  ? 121.591 138.371 66.824  1.00 27.87  ? 101 HIS A CA  1 
ATOM   606   C C   . HIS A 1 81  ? 122.773 137.655 66.185  1.00 28.03  ? 101 HIS A C   1 
ATOM   607   O O   . HIS A 1 81  ? 123.217 138.044 65.109  1.00 28.43  ? 101 HIS A O   1 
ATOM   608   C CB  . HIS A 1 81  ? 120.259 137.907 66.229  1.00 28.26  ? 101 HIS A CB  1 
ATOM   609   C CG  . HIS A 1 81  ? 119.839 136.559 66.700  1.00 28.87  ? 101 HIS A CG  1 
ATOM   610   N ND1 . HIS A 1 81  ? 119.583 135.512 65.844  1.00 29.36  ? 101 HIS A ND1 1 
ATOM   611   C CD2 . HIS A 1 81  ? 119.625 136.093 67.936  1.00 29.25  ? 101 HIS A CD2 1 
ATOM   612   C CE1 . HIS A 1 81  ? 119.229 134.451 66.554  1.00 29.73  ? 101 HIS A CE1 1 
ATOM   613   N NE2 . HIS A 1 81  ? 119.249 134.781 67.827  1.00 29.59  ? 101 HIS A NE2 1 
ATOM   614   N N   . SER A 1 82  ? 123.257 136.602 66.846  1.00 28.00  ? 102 SER A N   1 
ATOM   615   C CA  . SER A 1 82  ? 124.453 135.907 66.399  1.00 28.33  ? 102 SER A CA  1 
ATOM   616   C C   . SER A 1 82  ? 124.197 135.168 65.085  1.00 28.37  ? 102 SER A C   1 
ATOM   617   O O   . SER A 1 82  ? 125.086 135.104 64.240  1.00 28.88  ? 102 SER A O   1 
ATOM   618   C CB  . SER A 1 82  ? 124.965 134.977 67.464  1.00 28.93  ? 102 SER A CB  1 
ATOM   619   O OG  . SER A 1 82  ? 123.933 134.120 67.922  1.00 30.04  ? 102 SER A OG  1 
ATOM   620   N N   . ALA A 1 83  ? 122.985 134.623 64.911  1.00 28.32  ? 103 ALA A N   1 
ATOM   621   C CA  . ALA A 1 83  ? 122.664 133.830 63.733  1.00 28.56  ? 103 ALA A CA  1 
ATOM   622   C C   . ALA A 1 83  ? 122.533 134.724 62.501  1.00 28.91  ? 103 ALA A C   1 
ATOM   623   O O   . ALA A 1 83  ? 123.045 134.393 61.432  1.00 29.53  ? 103 ALA A O   1 
ATOM   624   C CB  . ALA A 1 83  ? 121.404 133.039 63.965  1.00 28.82  ? 103 ALA A CB  1 
ATOM   625   N N   . VAL A 1 84  ? 121.843 135.857 62.661  1.00 29.11  ? 104 VAL A N   1 
ATOM   626   C CA  . VAL A 1 84  ? 121.652 136.787 61.561  1.00 29.50  ? 104 VAL A CA  1 
ATOM   627   C C   . VAL A 1 84  ? 123.011 137.357 61.157  1.00 29.91  ? 104 VAL A C   1 
ATOM   628   O O   . VAL A 1 84  ? 123.305 137.498 59.970  1.00 30.60  ? 104 VAL A O   1 
ATOM   629   C CB  . VAL A 1 84  ? 120.659 137.908 61.918  1.00 29.58  ? 104 VAL A CB  1 
ATOM   630   C CG1 . VAL A 1 84  ? 120.375 138.797 60.716  1.00 30.08  ? 104 VAL A CG1 1 
ATOM   631   C CG2 . VAL A 1 84  ? 119.359 137.363 62.490  1.00 29.71  ? 104 VAL A CG2 1 
ATOM   632   N N   . ALA A 1 85  ? 123.841 137.671 62.157  1.00 30.00  ? 105 ALA A N   1 
ATOM   633   C CA  . ALA A 1 85  ? 125.169 138.202 61.905  1.00 30.53  ? 105 ALA A CA  1 
ATOM   634   C C   . ALA A 1 85  ? 126.017 137.170 61.168  1.00 31.15  ? 105 ALA A C   1 
ATOM   635   O O   . ALA A 1 85  ? 126.799 137.532 60.294  1.00 31.53  ? 105 ALA A O   1 
ATOM   636   C CB  . ALA A 1 85  ? 125.817 138.615 63.201  1.00 30.55  ? 105 ALA A CB  1 
ATOM   637   N N   . LEU A 1 86  ? 125.864 135.891 61.527  1.00 32.12  ? 106 LEU A N   1 
ATOM   638   C CA  . LEU A 1 86  ? 126.656 134.842 60.908  1.00 33.52  ? 106 LEU A CA  1 
ATOM   639   C C   . LEU A 1 86  ? 126.270 134.695 59.436  1.00 35.18  ? 106 LEU A C   1 
ATOM   640   O O   . LEU A 1 86  ? 127.143 134.532 58.589  1.00 35.58  ? 106 LEU A O   1 
ATOM   641   C CB  . LEU A 1 86  ? 126.477 133.532 61.683  1.00 33.28  ? 106 LEU A CB  1 
ATOM   642   C CG  . LEU A 1 86  ? 127.364 132.369 61.238  1.00 33.56  ? 106 LEU A CG  1 
ATOM   643   C CD1 . LEU A 1 86  ? 128.840 132.692 61.427  1.00 34.14  ? 106 LEU A CD1 1 
ATOM   644   C CD2 . LEU A 1 86  ? 127.007 131.102 61.996  1.00 33.54  ? 106 LEU A CD2 1 
ATOM   645   N N   . GLU A 1 87  ? 124.971 134.786 59.129  1.00 37.50  ? 107 GLU A N   1 
ATOM   646   C CA  . GLU A 1 87  ? 124.497 134.683 57.757  1.00 40.20  ? 107 GLU A CA  1 
ATOM   647   C C   . GLU A 1 87  ? 125.022 135.861 56.931  1.00 40.48  ? 107 GLU A C   1 
ATOM   648   O O   . GLU A 1 87  ? 125.453 135.693 55.787  1.00 41.56  ? 107 GLU A O   1 
ATOM   649   C CB  . GLU A 1 87  ? 122.967 134.656 57.750  1.00 43.26  ? 107 GLU A CB  1 
ATOM   650   C CG  . GLU A 1 87  ? 122.347 134.059 56.501  1.00 46.90  ? 107 GLU A CG  1 
ATOM   651   C CD  . GLU A 1 87  ? 120.827 134.084 56.505  1.00 50.44  ? 107 GLU A CD  1 
ATOM   652   O OE1 . GLU A 1 87  ? 120.224 133.572 55.537  1.00 52.09  ? 107 GLU A OE1 1 
ATOM   653   O OE2 . GLU A 1 87  ? 120.247 134.612 57.479  1.00 51.23  ? 107 GLU A OE2 1 
ATOM   654   N N   . GLN A 1 88  ? 124.996 137.063 57.525  1.00 39.61  ? 108 GLN A N   1 
ATOM   655   C CA  . GLN A 1 88  ? 125.460 138.257 56.837  1.00 38.77  ? 108 GLN A CA  1 
ATOM   656   C C   . GLN A 1 88  ? 126.971 138.184 56.620  1.00 38.82  ? 108 GLN A C   1 
ATOM   657   O O   . GLN A 1 88  ? 127.467 138.643 55.594  1.00 39.43  ? 108 GLN A O   1 
ATOM   658   C CB  . GLN A 1 88  ? 125.065 139.511 57.618  1.00 38.56  ? 108 GLN A CB  1 
ATOM   659   C CG  . GLN A 1 88  ? 123.561 139.686 57.776  1.00 38.39  ? 108 GLN A CG  1 
ATOM   660   C CD  . GLN A 1 88  ? 122.836 139.703 56.452  1.00 38.60  ? 108 GLN A CD  1 
ATOM   661   O OE1 . GLN A 1 88  ? 122.936 140.658 55.684  1.00 38.45  ? 108 GLN A OE1 1 
ATOM   662   N NE2 . GLN A 1 88  ? 122.089 138.644 56.180  1.00 38.98  ? 108 GLN A NE2 1 
ATOM   663   N N   . SER A 1 89  ? 127.701 137.598 57.575  1.00 38.95  ? 109 SER A N   1 
ATOM   664   C CA  . SER A 1 89  ? 129.140 137.445 57.433  1.00 39.69  ? 109 SER A CA  1 
ATOM   665   C C   . SER A 1 89  ? 129.458 136.442 56.325  1.00 41.31  ? 109 SER A C   1 
ATOM   666   O O   . SER A 1 89  ? 130.446 136.600 55.611  1.00 42.73  ? 109 SER A O   1 
ATOM   667   C CB  . SER A 1 89  ? 129.767 137.040 58.738  1.00 39.30  ? 109 SER A CB  1 
ATOM   668   O OG  . SER A 1 89  ? 129.372 137.919 59.776  1.00 38.81  ? 109 SER A OG  1 
ATOM   669   N N   . ILE A 1 90  ? 128.619 135.408 56.191  1.00 42.80  ? 110 ILE A N   1 
ATOM   670   C CA  . ILE A 1 90  ? 128.759 134.459 55.099  1.00 44.62  ? 110 ILE A CA  1 
ATOM   671   C C   . ILE A 1 90  ? 128.583 135.196 53.773  1.00 46.65  ? 110 ILE A C   1 
ATOM   672   O O   . ILE A 1 90  ? 129.297 134.918 52.809  1.00 48.01  ? 110 ILE A O   1 
ATOM   673   C CB  . ILE A 1 90  ? 127.786 133.273 55.254  1.00 44.90  ? 110 ILE A CB  1 
ATOM   674   C CG1 . ILE A 1 90  ? 128.305 132.273 56.290  1.00 45.06  ? 110 ILE A CG1 1 
ATOM   675   C CG2 . ILE A 1 90  ? 127.521 132.600 53.914  1.00 45.05  ? 110 ILE A CG2 1 
ATOM   676   C CD1 . ILE A 1 90  ? 127.302 131.213 56.679  1.00 45.63  ? 110 ILE A CD1 1 
ATOM   677   N N   . GLU A 1 91  ? 127.638 136.141 53.740  1.00 48.93  ? 111 GLU A N   1 
ATOM   678   C CA  . GLU A 1 91  ? 127.421 136.960 52.559  1.00 51.39  ? 111 GLU A CA  1 
ATOM   679   C C   . GLU A 1 91  ? 128.646 137.833 52.280  1.00 51.78  ? 111 GLU A C   1 
ATOM   680   O O   . GLU A 1 91  ? 128.955 138.106 51.124  1.00 51.97  ? 111 GLU A O   1 
ATOM   681   C CB  . GLU A 1 91  ? 126.162 137.808 52.732  1.00 53.49  ? 111 GLU A CB  1 
ATOM   682   C CG  . GLU A 1 91  ? 124.893 136.986 52.802  1.00 55.74  ? 111 GLU A CG  1 
ATOM   683   C CD  . GLU A 1 91  ? 124.510 136.312 51.494  1.00 58.83  ? 111 GLU A CD  1 
ATOM   684   O OE1 . GLU A 1 91  ? 125.063 136.673 50.431  1.00 59.00  ? 111 GLU A OE1 1 
ATOM   685   O OE2 . GLU A 1 91  ? 123.663 135.405 51.539  1.00 61.62  ? 111 GLU A OE2 1 
ATOM   686   N N   . PHE A 1 92  ? 129.334 138.282 53.337  1.00 52.62  ? 112 PHE A N   1 
ATOM   687   C CA  . PHE A 1 92  ? 130.572 139.028 53.174  1.00 53.78  ? 112 PHE A CA  1 
ATOM   688   C C   . PHE A 1 92  ? 131.640 138.169 52.502  1.00 59.24  ? 112 PHE A C   1 
ATOM   689   O O   . PHE A 1 92  ? 132.266 138.610 51.543  1.00 60.95  ? 112 PHE A O   1 
ATOM   690   C CB  . PHE A 1 92  ? 131.076 139.556 54.520  1.00 51.26  ? 112 PHE A CB  1 
ATOM   691   C CG  . PHE A 1 92  ? 130.425 140.832 54.988  1.00 49.49  ? 112 PHE A CG  1 
ATOM   692   C CD1 . PHE A 1 92  ? 129.829 141.712 54.092  1.00 49.07  ? 112 PHE A CD1 1 
ATOM   693   C CD2 . PHE A 1 92  ? 130.391 141.142 56.338  1.00 48.08  ? 112 PHE A CD2 1 
ATOM   694   C CE1 . PHE A 1 92  ? 129.234 142.881 54.535  1.00 48.27  ? 112 PHE A CE1 1 
ATOM   695   C CE2 . PHE A 1 92  ? 129.787 142.308 56.779  1.00 47.57  ? 112 PHE A CE2 1 
ATOM   696   C CZ  . PHE A 1 92  ? 129.212 143.175 55.877  1.00 47.75  ? 112 PHE A CZ  1 
ATOM   697   N N   . ILE A 1 93  ? 131.829 136.943 53.005  1.00 63.72  ? 113 ILE A N   1 
ATOM   698   C CA  . ILE A 1 93  ? 132.950 136.102 52.605  1.00 67.09  ? 113 ILE A CA  1 
ATOM   699   C C   . ILE A 1 93  ? 132.628 135.310 51.339  1.00 74.09  ? 113 ILE A C   1 
ATOM   700   O O   . ILE A 1 93  ? 133.487 134.580 50.844  1.00 75.11  ? 113 ILE A O   1 
ATOM   701   C CB  . ILE A 1 93  ? 133.333 135.122 53.727  1.00 66.31  ? 113 ILE A CB  1 
ATOM   702   C CG1 . ILE A 1 93  ? 132.270 134.030 53.878  1.00 66.87  ? 113 ILE A CG1 1 
ATOM   703   C CG2 . ILE A 1 93  ? 133.599 135.856 55.033  1.00 66.18  ? 113 ILE A CG2 1 
ATOM   704   C CD1 . ILE A 1 93  ? 132.780 132.749 54.462  1.00 66.96  ? 113 ILE A CD1 1 
ATOM   705   N N   . ARG A 1 94  ? 131.383 135.395 50.850  1.00 82.59  ? 114 ARG A N   1 
ATOM   706   C CA  . ARG A 1 94  ? 130.963 134.650 49.670  1.00 90.95  ? 114 ARG A CA  1 
ATOM   707   C C   . ARG A 1 94  ? 131.889 134.946 48.487  1.00 99.51  ? 114 ARG A C   1 
ATOM   708   O O   . ARG A 1 94  ? 132.136 134.064 47.667  1.00 99.14  ? 114 ARG A O   1 
ATOM   709   C CB  . ARG A 1 94  ? 129.507 134.975 49.323  1.00 92.83  ? 114 ARG A CB  1 
ATOM   710   C CG  . ARG A 1 94  ? 128.928 134.140 48.189  1.00 95.88  ? 114 ARG A CG  1 
ATOM   711   C CD  . ARG A 1 94  ? 127.569 134.624 47.723  1.00 99.23  ? 114 ARG A CD  1 
ATOM   712   N NE  . ARG A 1 94  ? 126.530 134.409 48.724  1.00 101.98 ? 114 ARG A NE  1 
ATOM   713   C CZ  . ARG A 1 94  ? 125.526 133.542 48.620  1.00 104.48 ? 114 ARG A CZ  1 
ATOM   714   N NH1 . ARG A 1 94  ? 125.439 132.723 47.585  1.00 104.62 ? 114 ARG A NH1 1 
ATOM   715   N NH2 . ARG A 1 94  ? 124.609 133.488 49.571  1.00 104.13 ? 114 ARG A NH2 1 
ATOM   716   N N   . ASP A 1 95  ? 132.404 136.178 48.408  1.00 109.66 ? 115 ASP A N   1 
ATOM   717   C CA  . ASP A 1 95  ? 133.260 136.598 47.309  1.00 118.66 ? 115 ASP A CA  1 
ATOM   718   C C   . ASP A 1 95  ? 134.577 135.819 47.325  1.00 119.87 ? 115 ASP A C   1 
ATOM   719   O O   . ASP A 1 95  ? 135.101 135.488 46.264  1.00 120.41 ? 115 ASP A O   1 
ATOM   720   C CB  . ASP A 1 95  ? 133.525 138.107 47.347  1.00 124.70 ? 115 ASP A CB  1 
ATOM   721   C CG  . ASP A 1 95  ? 132.262 138.951 47.318  1.00 129.49 ? 115 ASP A CG  1 
ATOM   722   O OD1 . ASP A 1 95  ? 131.303 138.532 46.640  1.00 130.76 ? 115 ASP A OD1 1 
ATOM   723   O OD2 . ASP A 1 95  ? 132.250 140.017 47.969  1.00 131.02 ? 115 ASP A OD2 1 
ATOM   724   N N   . SER A 1 96  ? 135.101 135.529 48.524  1.00 120.21 ? 116 SER A N   1 
ATOM   725   C CA  . SER A 1 96  ? 136.365 134.821 48.662  1.00 120.41 ? 116 SER A CA  1 
ATOM   726   C C   . SER A 1 96  ? 136.241 133.383 48.158  1.00 119.87 ? 116 SER A C   1 
ATOM   727   O O   . SER A 1 96  ? 137.206 132.839 47.622  1.00 119.09 ? 116 SER A O   1 
ATOM   728   C CB  . SER A 1 96  ? 136.865 134.845 50.086  1.00 119.00 ? 116 SER A CB  1 
ATOM   729   O OG  . SER A 1 96  ? 137.052 136.173 50.545  1.00 119.37 ? 116 SER A OG  1 
ATOM   730   N N   . LEU A 1 97  ? 135.063 132.771 48.340  1.00 117.30 ? 117 LEU A N   1 
ATOM   731   C CA  . LEU A 1 97  ? 134.848 131.392 47.925  1.00 115.58 ? 117 LEU A CA  1 
ATOM   732   C C   . LEU A 1 97  ? 134.727 131.326 46.397  1.00 116.30 ? 117 LEU A C   1 
ATOM   733   O O   . LEU A 1 97  ? 133.868 132.050 45.856  1.00 116.91 ? 117 LEU A O   1 
ATOM   734   C CB  . LEU A 1 97  ? 133.590 130.831 48.602  1.00 113.39 ? 117 LEU A CB  1 
ATOM   735   C CG  . LEU A 1 97  ? 133.643 130.669 50.123  1.00 110.81 ? 117 LEU A CG  1 
ATOM   736   C CD1 . LEU A 1 97  ? 132.391 129.971 50.631  1.00 110.03 ? 117 LEU A CD1 1 
ATOM   737   C CD2 . LEU A 1 97  ? 134.885 129.909 50.574  1.00 108.45 ? 117 LEU A CD2 1 
ATOM   738   N N   . LYS A 1 121 ? 133.930 141.945 44.473  1.00 87.55  ? 141 LYS A N   1 
ATOM   739   C CA  . LYS A 1 121 ? 135.090 142.639 45.094  1.00 87.17  ? 141 LYS A CA  1 
ATOM   740   C C   . LYS A 1 121 ? 135.238 142.166 46.538  1.00 82.59  ? 141 LYS A C   1 
ATOM   741   O O   . LYS A 1 121 ? 134.267 142.150 47.291  1.00 82.93  ? 141 LYS A O   1 
ATOM   742   C CB  . LYS A 1 121 ? 134.910 144.161 45.042  1.00 89.45  ? 141 LYS A CB  1 
ATOM   743   C CG  . LYS A 1 121 ? 134.612 144.726 43.658  1.00 92.20  ? 141 LYS A CG  1 
ATOM   744   C CD  . LYS A 1 121 ? 134.744 146.232 43.544  1.00 94.53  ? 141 LYS A CD  1 
ATOM   745   C CE  . LYS A 1 121 ? 136.176 146.718 43.627  1.00 95.86  ? 141 LYS A CE  1 
ATOM   746   N NZ  . LYS A 1 121 ? 136.290 148.147 43.247  1.00 95.91  ? 141 LYS A NZ  1 
ATOM   747   N N   . PRO A 1 122 ? 136.459 141.790 46.979  1.00 76.43  ? 142 PRO A N   1 
ATOM   748   C CA  . PRO A 1 122 ? 136.655 141.248 48.324  1.00 72.34  ? 142 PRO A CA  1 
ATOM   749   C C   . PRO A 1 122 ? 136.441 142.288 49.423  1.00 65.92  ? 142 PRO A C   1 
ATOM   750   O O   . PRO A 1 122 ? 136.762 143.460 49.246  1.00 65.65  ? 142 PRO A O   1 
ATOM   751   C CB  . PRO A 1 122 ? 138.113 140.763 48.303  1.00 74.59  ? 142 PRO A CB  1 
ATOM   752   C CG  . PRO A 1 122 ? 138.782 141.646 47.270  1.00 75.75  ? 142 PRO A CG  1 
ATOM   753   C CD  . PRO A 1 122 ? 137.717 141.900 46.224  1.00 76.30  ? 142 PRO A CD  1 
ATOM   754   N N   . ILE A 1 123 ? 135.874 141.837 50.547  1.00 59.77  ? 143 ILE A N   1 
ATOM   755   C CA  . ILE A 1 123 ? 135.715 142.666 51.729  1.00 55.29  ? 143 ILE A CA  1 
ATOM   756   C C   . ILE A 1 123 ? 137.024 142.629 52.507  1.00 51.32  ? 143 ILE A C   1 
ATOM   757   O O   . ILE A 1 123 ? 137.367 141.601 53.083  1.00 51.07  ? 143 ILE A O   1 
ATOM   758   C CB  . ILE A 1 123 ? 134.530 142.167 52.581  1.00 55.07  ? 143 ILE A CB  1 
ATOM   759   C CG1 . ILE A 1 123 ? 133.206 142.214 51.811  1.00 55.08  ? 143 ILE A CG1 1 
ATOM   760   C CG2 . ILE A 1 123 ? 134.441 142.932 53.891  1.00 54.81  ? 143 ILE A CG2 1 
ATOM   761   C CD1 . ILE A 1 123 ? 132.737 143.615 51.457  1.00 55.23  ? 143 ILE A CD1 1 
ATOM   762   N N   . VAL A 1 124 ? 137.741 143.754 52.530  1.00 48.02  ? 144 VAL A N   1 
ATOM   763   C CA  . VAL A 1 124 ? 139.052 143.808 53.159  1.00 46.07  ? 144 VAL A CA  1 
ATOM   764   C C   . VAL A 1 124 ? 138.908 143.724 54.677  1.00 42.79  ? 144 VAL A C   1 
ATOM   765   O O   . VAL A 1 124 ? 139.740 143.104 55.338  1.00 42.75  ? 144 VAL A O   1 
ATOM   766   C CB  . VAL A 1 124 ? 139.837 145.063 52.732  1.00 47.56  ? 144 VAL A CB  1 
ATOM   767   C CG1 . VAL A 1 124 ? 140.115 145.042 51.239  1.00 48.40  ? 144 VAL A CG1 1 
ATOM   768   C CG2 . VAL A 1 124 ? 139.145 146.361 53.132  1.00 47.93  ? 144 VAL A CG2 1 
ATOM   769   N N   . GLY A 1 125 ? 137.856 144.351 55.217  1.00 38.88  ? 145 GLY A N   1 
ATOM   770   C CA  . GLY A 1 125 ? 137.643 144.377 56.653  1.00 36.13  ? 145 GLY A CA  1 
ATOM   771   C C   . GLY A 1 125 ? 136.184 144.634 57.011  1.00 33.86  ? 145 GLY A C   1 
ATOM   772   O O   . GLY A 1 125 ? 135.391 145.003 56.155  1.00 34.15  ? 145 GLY A O   1 
ATOM   773   N N   . VAL A 1 126 ? 135.845 144.392 58.279  1.00 31.30  ? 146 VAL A N   1 
ATOM   774   C CA  . VAL A 1 126 ? 134.489 144.561 58.768  1.00 29.36  ? 146 VAL A CA  1 
ATOM   775   C C   . VAL A 1 126 ? 134.534 145.441 60.011  1.00 28.29  ? 146 VAL A C   1 
ATOM   776   O O   . VAL A 1 126 ? 135.393 145.245 60.865  1.00 28.17  ? 146 VAL A O   1 
ATOM   777   C CB  . VAL A 1 126 ? 133.866 143.194 59.099  1.00 29.05  ? 146 VAL A CB  1 
ATOM   778   C CG1 . VAL A 1 126 ? 132.533 143.334 59.815  1.00 29.09  ? 146 VAL A CG1 1 
ATOM   779   C CG2 . VAL A 1 126 ? 133.734 142.316 57.865  1.00 29.31  ? 146 VAL A CG2 1 
ATOM   780   N N   . ILE A 1 127 ? 133.575 146.367 60.125  1.00 27.10  ? 147 ILE A N   1 
ATOM   781   C CA  . ILE A 1 127 ? 133.410 147.155 61.333  1.00 26.02  ? 147 ILE A CA  1 
ATOM   782   C C   . ILE A 1 127 ? 132.486 146.379 62.263  1.00 25.26  ? 147 ILE A C   1 
ATOM   783   O O   . ILE A 1 127 ? 131.275 146.326 62.054  1.00 24.81  ? 147 ILE A O   1 
ATOM   784   C CB  . ILE A 1 127 ? 132.878 148.562 61.015  1.00 26.04  ? 147 ILE A CB  1 
ATOM   785   C CG1 . ILE A 1 127 ? 133.709 149.239 59.921  1.00 26.20  ? 147 ILE A CG1 1 
ATOM   786   C CG2 . ILE A 1 127 ? 132.792 149.404 62.281  1.00 26.17  ? 147 ILE A CG2 1 
ATOM   787   C CD1 . ILE A 1 127 ? 135.162 149.418 60.277  1.00 26.31  ? 147 ILE A CD1 1 
ATOM   788   N N   . GLY A 1 128 ? 133.101 145.782 63.287  1.00 25.19  ? 148 GLY A N   1 
ATOM   789   C CA  . GLY A 1 128 ? 132.520 144.674 64.021  1.00 24.87  ? 148 GLY A CA  1 
ATOM   790   C C   . GLY A 1 128 ? 131.158 145.017 64.607  1.00 24.56  ? 148 GLY A C   1 
ATOM   791   O O   . GLY A 1 128 ? 130.859 146.178 64.879  1.00 24.73  ? 148 GLY A O   1 
ATOM   792   N N   . PRO A 1 129 ? 130.304 143.999 64.841  1.00 23.90  ? 149 PRO A N   1 
ATOM   793   C CA  . PRO A 1 129 ? 128.981 144.224 65.419  1.00 23.58  ? 149 PRO A CA  1 
ATOM   794   C C   . PRO A 1 129 ? 129.063 144.750 66.848  1.00 23.31  ? 149 PRO A C   1 
ATOM   795   O O   . PRO A 1 129 ? 130.122 144.726 67.475  1.00 23.30  ? 149 PRO A O   1 
ATOM   796   C CB  . PRO A 1 129 ? 128.322 142.840 65.353  1.00 23.61  ? 149 PRO A CB  1 
ATOM   797   C CG  . PRO A 1 129 ? 129.485 141.878 65.341  1.00 23.64  ? 149 PRO A CG  1 
ATOM   798   C CD  . PRO A 1 129 ? 130.578 142.582 64.571  1.00 23.72  ? 149 PRO A CD  1 
ATOM   799   N N   . GLY A 1 130 ? 127.925 145.240 67.344  1.00 23.12  ? 150 GLY A N   1 
ATOM   800   C CA  . GLY A 1 130 ? 127.854 145.859 68.656  1.00 22.83  ? 150 GLY A CA  1 
ATOM   801   C C   . GLY A 1 130 ? 128.078 144.861 69.789  1.00 22.25  ? 150 GLY A C   1 
ATOM   802   O O   . GLY A 1 130 ? 128.827 145.137 70.720  1.00 22.63  ? 150 GLY A O   1 
ATOM   803   N N   . SER A 1 131 ? 127.439 143.694 69.693  1.00 21.78  ? 151 SER A N   1 
ATOM   804   C CA  . SER A 1 131 ? 127.435 142.736 70.781  1.00 21.75  ? 151 SER A CA  1 
ATOM   805   C C   . SER A 1 131 ? 128.755 141.976 70.820  1.00 21.45  ? 151 SER A C   1 
ATOM   806   O O   . SER A 1 131 ? 129.388 141.790 69.786  1.00 21.50  ? 151 SER A O   1 
ATOM   807   C CB  . SER A 1 131 ? 126.267 141.805 70.641  1.00 22.18  ? 151 SER A CB  1 
ATOM   808   O OG  . SER A 1 131 ? 126.173 140.946 71.761  1.00 22.44  ? 151 SER A OG  1 
ATOM   809   N N   . SER A 1 132 ? 129.152 141.521 72.011  1.00 21.49  ? 152 SER A N   1 
ATOM   810   C CA  . SER A 1 132 ? 130.390 140.776 72.167  1.00 21.51  ? 152 SER A CA  1 
ATOM   811   C C   . SER A 1 132 ? 130.225 139.352 71.645  1.00 21.66  ? 152 SER A C   1 
ATOM   812   O O   . SER A 1 132 ? 131.116 138.828 70.984  1.00 22.15  ? 152 SER A O   1 
ATOM   813   C CB  . SER A 1 132 ? 130.842 140.755 73.592  1.00 21.78  ? 152 SER A CB  1 
ATOM   814   O OG  . SER A 1 132 ? 131.092 142.063 74.066  1.00 22.28  ? 152 SER A OG  1 
ATOM   815   N N   . SER A 1 133 ? 129.089 138.723 71.962  1.00 21.52  ? 153 SER A N   1 
ATOM   816   C CA  . SER A 1 133 ? 128.837 137.352 71.549  1.00 21.47  ? 153 SER A CA  1 
ATOM   817   C C   . SER A 1 133 ? 128.681 137.283 70.031  1.00 20.81  ? 153 SER A C   1 
ATOM   818   O O   . SER A 1 133 ? 129.208 136.375 69.385  1.00 21.23  ? 153 SER A O   1 
ATOM   819   C CB  . SER A 1 133 ? 127.639 136.791 72.268  1.00 21.96  ? 153 SER A CB  1 
ATOM   820   O OG  . SER A 1 133 ? 126.529 137.671 72.176  1.00 22.14  ? 153 SER A OG  1 
ATOM   821   N N   . VAL A 1 134 ? 127.969 138.263 69.471  1.00 20.16  ? 154 VAL A N   1 
ATOM   822   C CA  . VAL A 1 134 ? 127.805 138.364 68.033  1.00 20.14  ? 154 VAL A CA  1 
ATOM   823   C C   . VAL A 1 134 ? 129.171 138.566 67.381  1.00 20.18  ? 154 VAL A C   1 
ATOM   824   O O   . VAL A 1 134 ? 129.464 137.969 66.348  1.00 20.49  ? 154 VAL A O   1 
ATOM   825   C CB  . VAL A 1 134 ? 126.828 139.496 67.668  1.00 20.35  ? 154 VAL A CB  1 
ATOM   826   C CG1 . VAL A 1 134 ? 126.804 139.756 66.173  1.00 20.32  ? 154 VAL A CG1 1 
ATOM   827   C CG2 . VAL A 1 134 ? 125.424 139.206 68.176  1.00 20.68  ? 154 VAL A CG2 1 
ATOM   828   N N   . ALA A 1 135 ? 130.001 139.418 67.991  1.00 20.19  ? 155 ALA A N   1 
ATOM   829   C CA  . ALA A 1 135 ? 131.334 139.692 67.482  1.00 20.11  ? 155 ALA A CA  1 
ATOM   830   C C   . ALA A 1 135 ? 132.176 138.423 67.511  1.00 20.14  ? 155 ALA A C   1 
ATOM   831   O O   . ALA A 1 135 ? 132.978 138.211 66.611  1.00 20.49  ? 155 ALA A O   1 
ATOM   832   C CB  . ALA A 1 135 ? 131.994 140.792 68.273  1.00 20.15  ? 155 ALA A CB  1 
ATOM   833   N N   . ILE A 1 136 ? 131.990 137.588 68.538  1.00 20.32  ? 156 ILE A N   1 
ATOM   834   C CA  . ILE A 1 136 ? 132.750 136.355 68.655  1.00 20.57  ? 156 ILE A CA  1 
ATOM   835   C C   . ILE A 1 136 ? 132.390 135.410 67.513  1.00 20.93  ? 156 ILE A C   1 
ATOM   836   O O   . ILE A 1 136 ? 133.282 134.820 66.912  1.00 21.24  ? 156 ILE A O   1 
ATOM   837   C CB  . ILE A 1 136 ? 132.547 135.707 70.036  1.00 20.72  ? 156 ILE A CB  1 
ATOM   838   C CG1 . ILE A 1 136 ? 133.351 136.456 71.101  1.00 20.89  ? 156 ILE A CG1 1 
ATOM   839   C CG2 . ILE A 1 136 ? 132.897 134.229 70.001  1.00 20.90  ? 156 ILE A CG2 1 
ATOM   840   C CD1 . ILE A 1 136 ? 133.269 135.850 72.479  1.00 21.02  ? 156 ILE A CD1 1 
ATOM   841   N N   . GLN A 1 137 ? 131.095 135.259 67.224  1.00 21.69  ? 157 GLN A N   1 
ATOM   842   C CA  . GLN A 1 137 ? 130.656 134.392 66.141  1.00 22.67  ? 157 GLN A CA  1 
ATOM   843   C C   . GLN A 1 137 ? 131.223 134.893 64.813  1.00 22.84  ? 157 GLN A C   1 
ATOM   844   O O   . GLN A 1 137 ? 131.783 134.117 64.037  1.00 23.48  ? 157 GLN A O   1 
ATOM   845   C CB  . GLN A 1 137 ? 129.130 134.308 66.073  1.00 23.71  ? 157 GLN A CB  1 
ATOM   846   C CG  . GLN A 1 137 ? 128.564 132.948 66.466  1.00 24.92  ? 157 GLN A CG  1 
ATOM   847   C CD  . GLN A 1 137 ? 128.949 132.519 67.863  1.00 26.11  ? 157 GLN A CD  1 
ATOM   848   O OE1 . GLN A 1 137 ? 128.714 133.233 68.837  1.00 26.61  ? 157 GLN A OE1 1 
ATOM   849   N NE2 . GLN A 1 137 ? 129.553 131.345 67.972  1.00 26.38  ? 157 GLN A NE2 1 
ATOM   850   N N   . VAL A 1 138 ? 131.076 136.196 64.567  1.00 22.58  ? 158 VAL A N   1 
ATOM   851   C CA  . VAL A 1 138 ? 131.515 136.794 63.318  1.00 22.41  ? 158 VAL A CA  1 
ATOM   852   C C   . VAL A 1 138 ? 133.031 136.651 63.183  1.00 21.99  ? 158 VAL A C   1 
ATOM   853   O O   . VAL A 1 138 ? 133.531 136.412 62.089  1.00 22.17  ? 158 VAL A O   1 
ATOM   854   C CB  . VAL A 1 138 ? 131.066 138.264 63.224  1.00 22.75  ? 158 VAL A CB  1 
ATOM   855   C CG1 . VAL A 1 138 ? 131.712 138.992 62.055  1.00 22.87  ? 158 VAL A CG1 1 
ATOM   856   C CG2 . VAL A 1 138 ? 129.552 138.369 63.146  1.00 22.88  ? 158 VAL A CG2 1 
ATOM   857   N N   . GLN A 1 139 ? 133.754 136.793 64.298  1.00 21.89  ? 159 GLN A N   1 
ATOM   858   C CA  . GLN A 1 139 ? 135.205 136.709 64.282  1.00 22.07  ? 159 GLN A CA  1 
ATOM   859   C C   . GLN A 1 139 ? 135.634 135.277 63.981  1.00 22.33  ? 159 GLN A C   1 
ATOM   860   O O   . GLN A 1 139 ? 136.584 135.071 63.230  1.00 22.70  ? 159 GLN A O   1 
ATOM   861   C CB  . GLN A 1 139 ? 135.787 137.197 65.610  1.00 22.00  ? 159 GLN A CB  1 
ATOM   862   C CG  . GLN A 1 139 ? 137.280 136.971 65.766  1.00 22.02  ? 159 GLN A CG  1 
ATOM   863   C CD  . GLN A 1 139 ? 138.160 137.603 64.716  1.00 22.19  ? 159 GLN A CD  1 
ATOM   864   O OE1 . GLN A 1 139 ? 137.723 138.042 63.656  1.00 22.08  ? 159 GLN A OE1 1 
ATOM   865   N NE2 . GLN A 1 139 ? 139.449 137.621 65.007  1.00 22.80  ? 159 GLN A NE2 1 
ATOM   866   N N   . ASN A 1 140 ? 134.950 134.299 64.582  1.00 22.44  ? 160 ASN A N   1 
ATOM   867   C CA  . ASN A 1 140 ? 135.247 132.903 64.312  1.00 22.72  ? 160 ASN A CA  1 
ATOM   868   C C   . ASN A 1 140 ? 135.144 132.642 62.813  1.00 23.39  ? 160 ASN A C   1 
ATOM   869   O O   . ASN A 1 140 ? 135.947 131.895 62.265  1.00 23.81  ? 160 ASN A O   1 
ATOM   870   C CB  . ASN A 1 140 ? 134.349 131.949 65.098  1.00 22.67  ? 160 ASN A CB  1 
ATOM   871   C CG  . ASN A 1 140 ? 134.656 131.952 66.580  1.00 22.94  ? 160 ASN A CG  1 
ATOM   872   O OD1 . ASN A 1 140 ? 135.820 131.931 66.973  1.00 23.19  ? 160 ASN A OD1 1 
ATOM   873   N ND2 . ASN A 1 140 ? 133.627 131.994 67.410  1.00 23.13  ? 160 ASN A ND2 1 
ATOM   874   N N   . LEU A 1 141 ? 134.168 133.260 62.144  1.00 24.07  ? 161 LEU A N   1 
ATOM   875   C CA  . LEU A 1 141 ? 134.038 133.034 60.716  1.00 24.50  ? 161 LEU A CA  1 
ATOM   876   C C   . LEU A 1 141 ? 135.087 133.831 59.948  1.00 24.60  ? 161 LEU A C   1 
ATOM   877   O O   . LEU A 1 141 ? 135.617 133.320 58.971  1.00 25.00  ? 161 LEU A O   1 
ATOM   878   C CB  . LEU A 1 141 ? 132.640 133.396 60.215  1.00 25.16  ? 161 LEU A CB  1 
ATOM   879   C CG  . LEU A 1 141 ? 132.424 133.041 58.744  1.00 25.86  ? 161 LEU A CG  1 
ATOM   880   C CD1 . LEU A 1 141 ? 132.084 131.570 58.593  1.00 26.26  ? 161 LEU A CD1 1 
ATOM   881   C CD2 . LEU A 1 141 ? 131.348 133.900 58.116  1.00 26.36  ? 161 LEU A CD2 1 
ATOM   882   N N   . LEU A 1 142 ? 135.364 135.073 60.366  1.00 25.09  ? 162 LEU A N   1 
ATOM   883   C CA  . LEU A 1 142 ? 136.174 135.985 59.566  1.00 25.48  ? 162 LEU A CA  1 
ATOM   884   C C   . LEU A 1 142 ? 137.653 135.600 59.606  1.00 26.16  ? 162 LEU A C   1 
ATOM   885   O O   . LEU A 1 142 ? 138.339 135.704 58.591  1.00 26.58  ? 162 LEU A O   1 
ATOM   886   C CB  . LEU A 1 142 ? 135.987 137.428 60.054  1.00 25.19  ? 162 LEU A CB  1 
ATOM   887   C CG  . LEU A 1 142 ? 134.665 138.109 59.691  1.00 24.87  ? 162 LEU A CG  1 
ATOM   888   C CD1 . LEU A 1 142 ? 134.753 139.609 59.917  1.00 24.62  ? 162 LEU A CD1 1 
ATOM   889   C CD2 . LEU A 1 142 ? 134.259 137.828 58.252  1.00 24.98  ? 162 LEU A CD2 1 
ATOM   890   N N   . GLN A 1 143 ? 138.146 135.161 60.771  1.00 26.56  ? 163 GLN A N   1 
ATOM   891   C CA  . GLN A 1 143 ? 139.571 134.915 60.937  1.00 27.04  ? 163 GLN A CA  1 
ATOM   892   C C   . GLN A 1 143 ? 140.059 133.823 59.987  1.00 27.97  ? 163 GLN A C   1 
ATOM   893   O O   . GLN A 1 143 ? 141.254 133.740 59.723  1.00 28.70  ? 163 GLN A O   1 
ATOM   894   C CB  . GLN A 1 143 ? 139.908 134.540 62.379  1.00 26.78  ? 163 GLN A CB  1 
ATOM   895   C CG  . GLN A 1 143 ? 139.359 133.193 62.816  1.00 26.94  ? 163 GLN A CG  1 
ATOM   896   C CD  . GLN A 1 143 ? 139.673 132.909 64.263  1.00 27.29  ? 163 GLN A CD  1 
ATOM   897   O OE1 . GLN A 1 143 ? 140.366 133.675 64.926  1.00 27.06  ? 163 GLN A OE1 1 
ATOM   898   N NE2 . GLN A 1 143 ? 139.173 131.790 64.764  1.00 27.72  ? 163 GLN A NE2 1 
ATOM   899   N N   . LEU A 1 144 ? 139.147 132.984 59.483  1.00 28.72  ? 164 LEU A N   1 
ATOM   900   C CA  . LEU A 1 144 ? 139.520 131.941 58.540  1.00 29.78  ? 164 LEU A CA  1 
ATOM   901   C C   . LEU A 1 144 ? 139.927 132.553 57.201  1.00 31.40  ? 164 LEU A C   1 
ATOM   902   O O   . LEU A 1 144 ? 140.684 131.934 56.458  1.00 32.30  ? 164 LEU A O   1 
ATOM   903   C CB  . LEU A 1 144 ? 138.351 130.971 58.347  1.00 29.94  ? 164 LEU A CB  1 
ATOM   904   C CG  . LEU A 1 144 ? 137.819 130.289 59.606  1.00 30.36  ? 164 LEU A CG  1 
ATOM   905   C CD1 . LEU A 1 144 ? 136.786 129.235 59.240  1.00 30.51  ? 164 LEU A CD1 1 
ATOM   906   C CD2 . LEU A 1 144 ? 138.942 129.670 60.425  1.00 30.62  ? 164 LEU A CD2 1 
ATOM   907   N N   . PHE A 1 145 ? 139.423 133.756 56.894  1.00 32.88  ? 165 PHE A N   1 
ATOM   908   C CA  . PHE A 1 145 ? 139.663 134.381 55.601  1.00 34.27  ? 165 PHE A CA  1 
ATOM   909   C C   . PHE A 1 145 ? 140.588 135.591 55.727  1.00 33.88  ? 165 PHE A C   1 
ATOM   910   O O   . PHE A 1 145 ? 140.791 136.306 54.748  1.00 33.95  ? 165 PHE A O   1 
ATOM   911   C CB  . PHE A 1 145 ? 138.334 134.777 54.955  1.00 35.65  ? 165 PHE A CB  1 
ATOM   912   C CG  . PHE A 1 145 ? 137.469 133.611 54.554  1.00 37.36  ? 165 PHE A CG  1 
ATOM   913   C CD1 . PHE A 1 145 ? 136.814 132.849 55.507  1.00 37.57  ? 165 PHE A CD1 1 
ATOM   914   C CD2 . PHE A 1 145 ? 137.320 133.269 53.219  1.00 39.26  ? 165 PHE A CD2 1 
ATOM   915   C CE1 . PHE A 1 145 ? 136.026 131.771 55.136  1.00 38.40  ? 165 PHE A CE1 1 
ATOM   916   C CE2 . PHE A 1 145 ? 136.528 132.191 52.849  1.00 40.06  ? 165 PHE A CE2 1 
ATOM   917   C CZ  . PHE A 1 145 ? 135.885 131.443 53.809  1.00 39.57  ? 165 PHE A CZ  1 
ATOM   918   N N   . ASN A 1 146 ? 141.154 135.809 56.923  1.00 34.00  ? 166 ASN A N   1 
ATOM   919   C CA  . ASN A 1 146 ? 142.072 136.912 57.170  1.00 34.45  ? 166 ASN A CA  1 
ATOM   920   C C   . ASN A 1 146 ? 141.381 138.235 56.848  1.00 33.66  ? 166 ASN A C   1 
ATOM   921   O O   . ASN A 1 146 ? 141.829 138.986 55.982  1.00 34.21  ? 166 ASN A O   1 
ATOM   922   C CB  . ASN A 1 146 ? 143.377 136.753 56.383  1.00 35.85  ? 166 ASN A CB  1 
ATOM   923   C CG  . ASN A 1 146 ? 144.083 135.447 56.679  1.00 36.95  ? 166 ASN A CG  1 
ATOM   924   O OD1 . ASN A 1 146 ? 144.359 135.139 57.836  1.00 37.05  ? 166 ASN A OD1 1 
ATOM   925   N ND2 . ASN A 1 146 ? 144.372 134.671 55.647  1.00 37.64  ? 166 ASN A ND2 1 
ATOM   926   N N   . ILE A 1 147 ? 140.285 138.508 57.562  1.00 32.29  ? 167 ILE A N   1 
ATOM   927   C CA  . ILE A 1 147 ? 139.557 139.756 57.420  1.00 31.13  ? 167 ILE A CA  1 
ATOM   928   C C   . ILE A 1 147 ? 139.567 140.454 58.773  1.00 29.83  ? 167 ILE A C   1 
ATOM   929   O O   . ILE A 1 147 ? 138.848 140.047 59.681  1.00 29.80  ? 167 ILE A O   1 
ATOM   930   C CB  . ILE A 1 147 ? 138.126 139.509 56.907  1.00 31.36  ? 167 ILE A CB  1 
ATOM   931   C CG1 . ILE A 1 147 ? 138.136 138.789 55.558  1.00 31.76  ? 167 ILE A CG1 1 
ATOM   932   C CG2 . ILE A 1 147 ? 137.341 140.810 56.848  1.00 31.51  ? 167 ILE A CG2 1 
ATOM   933   C CD1 . ILE A 1 147 ? 136.762 138.497 55.003  1.00 32.33  ? 167 ILE A CD1 1 
ATOM   934   N N   . PRO A 1 148 ? 140.389 141.511 58.953  1.00 28.89  ? 168 PRO A N   1 
ATOM   935   C CA  . PRO A 1 148 ? 140.412 142.256 60.210  1.00 28.22  ? 168 PRO A CA  1 
ATOM   936   C C   . PRO A 1 148 ? 139.035 142.807 60.564  1.00 27.02  ? 168 PRO A C   1 
ATOM   937   O O   . PRO A 1 148 ? 138.283 143.219 59.687  1.00 27.28  ? 168 PRO A O   1 
ATOM   938   C CB  . PRO A 1 148 ? 141.408 143.390 59.942  1.00 28.89  ? 168 PRO A CB  1 
ATOM   939   C CG  . PRO A 1 148 ? 142.288 142.856 58.840  1.00 29.22  ? 168 PRO A CG  1 
ATOM   940   C CD  . PRO A 1 148 ? 141.359 142.032 57.977  1.00 29.11  ? 168 PRO A CD  1 
ATOM   941   N N   . GLN A 1 149 ? 138.723 142.793 61.859  1.00 25.79  ? 169 GLN A N   1 
ATOM   942   C CA  . GLN A 1 149 ? 137.426 143.210 62.355  1.00 24.95  ? 169 GLN A CA  1 
ATOM   943   C C   . GLN A 1 149 ? 137.642 144.205 63.485  1.00 24.56  ? 169 GLN A C   1 
ATOM   944   O O   . GLN A 1 149 ? 138.164 143.835 64.531  1.00 25.27  ? 169 GLN A O   1 
ATOM   945   C CB  . GLN A 1 149 ? 136.656 141.989 62.856  1.00 24.78  ? 169 GLN A CB  1 
ATOM   946   C CG  . GLN A 1 149 ? 135.322 142.322 63.503  1.00 24.71  ? 169 GLN A CG  1 
ATOM   947   C CD  . GLN A 1 149 ? 134.686 141.102 64.126  1.00 24.58  ? 169 GLN A CD  1 
ATOM   948   O OE1 . GLN A 1 149 ? 134.796 139.991 63.615  1.00 24.68  ? 169 GLN A OE1 1 
ATOM   949   N NE2 . GLN A 1 149 ? 134.024 141.295 65.254  1.00 24.71  ? 169 GLN A NE2 1 
ATOM   950   N N   . ILE A 1 150 ? 137.238 145.459 63.269  1.00 24.01  ? 170 ILE A N   1 
ATOM   951   C CA  . ILE A 1 150 ? 137.379 146.484 64.287  1.00 23.94  ? 170 ILE A CA  1 
ATOM   952   C C   . ILE A 1 150 ? 136.002 146.771 64.870  1.00 23.55  ? 170 ILE A C   1 
ATOM   953   O O   . ILE A 1 150 ? 135.127 147.277 64.171  1.00 23.93  ? 170 ILE A O   1 
ATOM   954   C CB  . ILE A 1 150 ? 138.050 147.754 63.730  1.00 24.47  ? 170 ILE A CB  1 
ATOM   955   C CG1 . ILE A 1 150 ? 139.374 147.434 63.036  1.00 25.07  ? 170 ILE A CG1 1 
ATOM   956   C CG2 . ILE A 1 150 ? 138.246 148.784 64.826  1.00 24.62  ? 170 ILE A CG2 1 
ATOM   957   C CD1 . ILE A 1 150 ? 139.227 147.038 61.596  1.00 25.59  ? 170 ILE A CD1 1 
ATOM   958   N N   . ALA A 1 151 ? 135.827 146.430 66.152  1.00 23.32  ? 171 ALA A N   1 
ATOM   959   C CA  . ALA A 1 151 ? 134.582 146.680 66.856  1.00 23.57  ? 171 ALA A CA  1 
ATOM   960   C C   . ALA A 1 151 ? 134.582 148.093 67.430  1.00 23.67  ? 171 ALA A C   1 
ATOM   961   O O   . ALA A 1 151 ? 135.599 148.780 67.418  1.00 23.99  ? 171 ALA A O   1 
ATOM   962   C CB  . ALA A 1 151 ? 134.392 145.654 67.941  1.00 23.81  ? 171 ALA A CB  1 
ATOM   963   N N   . TYR A 1 152 ? 133.413 148.523 67.911  1.00 23.85  ? 172 TYR A N   1 
ATOM   964   C CA  . TYR A 1 152 ? 133.259 149.835 68.517  1.00 23.95  ? 172 TYR A CA  1 
ATOM   965   C C   . TYR A 1 152 ? 132.556 149.738 69.869  1.00 24.33  ? 172 TYR A C   1 
ATOM   966   O O   . TYR A 1 152 ? 132.604 150.694 70.639  1.00 24.46  ? 172 TYR A O   1 
ATOM   967   C CB  . TYR A 1 152 ? 132.508 150.771 67.568  1.00 24.11  ? 172 TYR A CB  1 
ATOM   968   C CG  . TYR A 1 152 ? 131.292 150.156 66.928  1.00 24.47  ? 172 TYR A CG  1 
ATOM   969   C CD1 . TYR A 1 152 ? 130.138 149.942 67.659  1.00 24.59  ? 172 TYR A CD1 1 
ATOM   970   C CD2 . TYR A 1 152 ? 131.310 149.747 65.604  1.00 24.69  ? 172 TYR A CD2 1 
ATOM   971   C CE1 . TYR A 1 152 ? 129.016 149.368 67.084  1.00 24.83  ? 172 TYR A CE1 1 
ATOM   972   C CE2 . TYR A 1 152 ? 130.199 149.170 65.012  1.00 24.73  ? 172 TYR A CE2 1 
ATOM   973   C CZ  . TYR A 1 152 ? 129.050 148.972 65.758  1.00 24.80  ? 172 TYR A CZ  1 
ATOM   974   O OH  . TYR A 1 152 ? 127.943 148.386 65.198  1.00 24.86  ? 172 TYR A OH  1 
ATOM   975   N N   . SER A 1 153 ? 131.884 148.612 70.156  1.00 24.88  ? 173 SER A N   1 
ATOM   976   C CA  . SER A 1 153 ? 131.203 148.447 71.433  1.00 25.16  ? 173 SER A CA  1 
ATOM   977   C C   . SER A 1 153 ? 131.406 147.060 72.046  1.00 24.90  ? 173 SER A C   1 
ATOM   978   O O   . SER A 1 153 ? 130.999 146.850 73.184  1.00 25.37  ? 173 SER A O   1 
ATOM   979   C CB  . SER A 1 153 ? 129.737 148.776 71.308  1.00 25.77  ? 173 SER A CB  1 
ATOM   980   O OG  . SER A 1 153 ? 129.186 148.227 70.123  1.00 26.09  ? 173 SER A OG  1 
ATOM   981   N N   . ALA A 1 154 ? 132.028 146.118 71.327  1.00 24.80  ? 174 ALA A N   1 
ATOM   982   C CA  . ALA A 1 154 ? 132.352 144.829 71.922  1.00 25.17  ? 174 ALA A CA  1 
ATOM   983   C C   . ALA A 1 154 ? 133.363 145.040 73.047  1.00 26.35  ? 174 ALA A C   1 
ATOM   984   O O   . ALA A 1 154 ? 134.431 145.595 72.809  1.00 27.07  ? 174 ALA A O   1 
ATOM   985   C CB  . ALA A 1 154 ? 132.889 143.889 70.875  1.00 24.91  ? 174 ALA A CB  1 
ATOM   986   N N   . THR A 1 155 ? 133.020 144.608 74.268  1.00 27.54  ? 175 THR A N   1 
ATOM   987   C CA  . THR A 1 155 ? 133.768 145.008 75.450  1.00 28.76  ? 175 THR A CA  1 
ATOM   988   C C   . THR A 1 155 ? 134.228 143.814 76.290  1.00 29.83  ? 175 THR A C   1 
ATOM   989   O O   . THR A 1 155 ? 135.042 143.998 77.191  1.00 30.85  ? 175 THR A O   1 
ATOM   990   C CB  . THR A 1 155 ? 132.940 145.972 76.310  1.00 29.58  ? 175 THR A CB  1 
ATOM   991   O OG1 . THR A 1 155 ? 132.259 146.877 75.441  1.00 29.89  ? 175 THR A OG1 1 
ATOM   992   C CG2 . THR A 1 155 ? 133.767 146.779 77.287  1.00 30.48  ? 175 THR A CG2 1 
ATOM   993   N N   . SER A 1 156 ? 133.741 142.601 76.004  1.00 30.84  ? 176 SER A N   1 
ATOM   994   C CA  . SER A 1 156 ? 134.087 141.450 76.825  1.00 32.29  ? 176 SER A CA  1 
ATOM   995   C C   . SER A 1 156 ? 135.589 141.186 76.759  1.00 34.05  ? 176 SER A C   1 
ATOM   996   O O   . SER A 1 156 ? 136.224 141.439 75.739  1.00 34.26  ? 176 SER A O   1 
ATOM   997   C CB  . SER A 1 156 ? 133.307 140.229 76.425  1.00 32.41  ? 176 SER A CB  1 
ATOM   998   O OG  . SER A 1 156 ? 133.637 139.838 75.101  1.00 32.44  ? 176 SER A OG  1 
ATOM   999   N N   . MET A 1 157 ? 136.136 140.651 77.856  1.00 36.66  ? 177 MET A N   1 
ATOM   1000  C CA  . MET A 1 157 ? 137.558 140.372 77.967  1.00 39.53  ? 177 MET A CA  1 
ATOM   1001  C C   . MET A 1 157 ? 137.939 139.178 77.096  1.00 39.81  ? 177 MET A C   1 
ATOM   1002  O O   . MET A 1 157 ? 139.109 139.013 76.759  1.00 40.51  ? 177 MET A O   1 
ATOM   1003  C CB  . MET A 1 157 ? 137.926 140.032 79.412  1.00 42.41  ? 177 MET A CB  1 
ATOM   1004  C CG  . MET A 1 157 ? 137.927 141.228 80.338  1.00 44.98  ? 177 MET A CG  1 
ATOM   1005  S SD  . MET A 1 157 ? 138.133 140.767 82.086  1.00 48.52  ? 177 MET A SD  1 
ATOM   1006  C CE  . MET A 1 157 ? 137.058 139.339 82.241  1.00 49.50  ? 177 MET A CE  1 
ATOM   1007  N N   . ASP A 1 158 ? 136.954 138.338 76.761  1.00 39.57  ? 178 ASP A N   1 
ATOM   1008  C CA  . ASP A 1 158 ? 137.203 137.131 75.992  1.00 39.53  ? 178 ASP A CA  1 
ATOM   1009  C C   . ASP A 1 158 ? 137.820 137.478 74.641  1.00 37.77  ? 178 ASP A C   1 
ATOM   1010  O O   . ASP A 1 158 ? 138.626 136.712 74.123  1.00 38.11  ? 178 ASP A O   1 
ATOM   1011  C CB  . ASP A 1 158 ? 135.919 136.317 75.829  1.00 41.12  ? 178 ASP A CB  1 
ATOM   1012  C CG  . ASP A 1 158 ? 135.396 135.790 77.151  1.00 42.98  ? 178 ASP A CG  1 
ATOM   1013  O OD1 . ASP A 1 158 ? 135.971 136.167 78.198  1.00 43.66  ? 178 ASP A OD1 1 
ATOM   1014  O OD2 . ASP A 1 158 ? 134.430 135.003 77.126  1.00 44.01  ? 178 ASP A OD2 1 
ATOM   1015  N N   . LEU A 1 159 ? 137.452 138.637 74.088  1.00 36.34  ? 179 LEU A N   1 
ATOM   1016  C CA  . LEU A 1 159 ? 137.936 139.051 72.781  1.00 35.61  ? 179 LEU A CA  1 
ATOM   1017  C C   . LEU A 1 159 ? 139.377 139.562 72.848  1.00 36.52  ? 179 LEU A C   1 
ATOM   1018  O O   . LEU A 1 159 ? 139.989 139.780 71.805  1.00 36.61  ? 179 LEU A O   1 
ATOM   1019  C CB  . LEU A 1 159 ? 136.990 140.124 72.239  1.00 34.42  ? 179 LEU A CB  1 
ATOM   1020  C CG  . LEU A 1 159 ? 135.666 139.601 71.685  1.00 33.82  ? 179 LEU A CG  1 
ATOM   1021  C CD1 . LEU A 1 159 ? 134.632 140.709 71.614  1.00 34.10  ? 179 LEU A CD1 1 
ATOM   1022  C CD2 . LEU A 1 159 ? 135.864 138.985 70.310  1.00 33.67  ? 179 LEU A CD2 1 
ATOM   1023  N N   . SER A 1 160 ? 139.918 139.756 74.059  1.00 37.90  ? 180 SER A N   1 
ATOM   1024  C CA  . SER A 1 160 ? 141.278 140.252 74.224  1.00 39.36  ? 180 SER A CA  1 
ATOM   1025  C C   . SER A 1 160 ? 142.305 139.154 73.940  1.00 41.17  ? 180 SER A C   1 
ATOM   1026  O O   . SER A 1 160 ? 143.458 139.451 73.642  1.00 41.70  ? 180 SER A O   1 
ATOM   1027  C CB  . SER A 1 160 ? 141.489 140.832 75.602  1.00 39.39  ? 180 SER A CB  1 
ATOM   1028  O OG  . SER A 1 160 ? 140.737 142.020 75.785  1.00 39.04  ? 180 SER A OG  1 
ATOM   1029  N N   . ASP A 1 161 ? 141.894 137.885 74.050  1.00 43.11  ? 181 ASP A N   1 
ATOM   1030  C CA  . ASP A 1 161 ? 142.774 136.754 73.798  1.00 44.71  ? 181 ASP A CA  1 
ATOM   1031  C C   . ASP A 1 161 ? 143.072 136.674 72.300  1.00 43.38  ? 181 ASP A C   1 
ATOM   1032  O O   . ASP A 1 161 ? 142.200 136.307 71.519  1.00 43.09  ? 181 ASP A O   1 
ATOM   1033  C CB  . ASP A 1 161 ? 142.143 135.464 74.336  1.00 47.18  ? 181 ASP A CB  1 
ATOM   1034  C CG  . ASP A 1 161 ? 142.927 134.194 74.048  1.00 49.95  ? 181 ASP A CG  1 
ATOM   1035  O OD1 . ASP A 1 161 ? 143.382 134.050 72.897  1.00 50.07  ? 181 ASP A OD1 1 
ATOM   1036  O OD2 . ASP A 1 161 ? 143.064 133.355 74.972  1.00 51.76  ? 181 ASP A OD2 1 
ATOM   1037  N N   . LYS A 1 162 ? 144.322 136.957 71.920  1.00 42.51  ? 182 LYS A N   1 
ATOM   1038  C CA  . LYS A 1 162 ? 144.695 137.021 70.514  1.00 41.94  ? 182 LYS A CA  1 
ATOM   1039  C C   . LYS A 1 162 ? 145.071 135.656 69.949  1.00 42.07  ? 182 LYS A C   1 
ATOM   1040  O O   . LYS A 1 162 ? 145.301 135.545 68.746  1.00 42.52  ? 182 LYS A O   1 
ATOM   1041  C CB  . LYS A 1 162 ? 145.810 138.044 70.287  1.00 41.81  ? 182 LYS A CB  1 
ATOM   1042  C CG  . LYS A 1 162 ? 145.310 139.388 69.779  1.00 41.90  ? 182 LYS A CG  1 
ATOM   1043  C CD  . LYS A 1 162 ? 144.028 139.827 70.438  1.00 41.26  ? 182 LYS A CD  1 
ATOM   1044  C CE  . LYS A 1 162 ? 143.218 140.781 69.596  1.00 40.83  ? 182 LYS A CE  1 
ATOM   1045  N NZ  . LYS A 1 162 ? 141.892 140.999 70.219  1.00 40.90  ? 182 LYS A NZ  1 
ATOM   1046  N N   . THR A 1 163 ? 145.110 134.622 70.792  1.00 41.41  ? 183 THR A N   1 
ATOM   1047  C CA  . THR A 1 163 ? 145.322 133.267 70.308  1.00 40.47  ? 183 THR A CA  1 
ATOM   1048  C C   . THR A 1 163 ? 144.047 132.768 69.631  1.00 39.46  ? 183 THR A C   1 
ATOM   1049  O O   . THR A 1 163 ? 144.113 132.121 68.589  1.00 39.54  ? 183 THR A O   1 
ATOM   1050  C CB  . THR A 1 163 ? 145.762 132.327 71.437  1.00 40.81  ? 183 THR A CB  1 
ATOM   1051  O OG1 . THR A 1 163 ? 146.840 132.948 72.138  1.00 40.80  ? 183 THR A OG1 1 
ATOM   1052  C CG2 . THR A 1 163 ? 146.183 130.964 70.936  1.00 41.35  ? 183 THR A CG2 1 
ATOM   1053  N N   . LEU A 1 164 ? 142.891 133.081 70.231  1.00 38.38  ? 184 LEU A N   1 
ATOM   1054  C CA  . LEU A 1 164 ? 141.605 132.648 69.708  1.00 37.68  ? 184 LEU A CA  1 
ATOM   1055  C C   . LEU A 1 164 ? 141.060 133.665 68.707  1.00 36.45  ? 184 LEU A C   1 
ATOM   1056  O O   . LEU A 1 164 ? 140.438 133.283 67.720  1.00 36.37  ? 184 LEU A O   1 
ATOM   1057  C CB  . LEU A 1 164 ? 140.626 132.465 70.871  1.00 38.59  ? 184 LEU A CB  1 
ATOM   1058  C CG  . LEU A 1 164 ? 141.074 131.523 71.988  1.00 39.62  ? 184 LEU A CG  1 
ATOM   1059  C CD1 . LEU A 1 164 ? 140.014 131.444 73.070  1.00 40.44  ? 184 LEU A CD1 1 
ATOM   1060  C CD2 . LEU A 1 164 ? 141.394 130.132 71.457  1.00 39.92  ? 184 LEU A CD2 1 
ATOM   1061  N N   . PHE A 1 165 ? 141.263 134.958 68.987  1.00 34.77  ? 185 PHE A N   1 
ATOM   1062  C CA  . PHE A 1 165 ? 140.729 136.027 68.159  1.00 33.03  ? 185 PHE A CA  1 
ATOM   1063  C C   . PHE A 1 165 ? 141.872 136.912 67.673  1.00 32.87  ? 185 PHE A C   1 
ATOM   1064  O O   . PHE A 1 165 ? 142.189 137.924 68.296  1.00 33.29  ? 185 PHE A O   1 
ATOM   1065  C CB  . PHE A 1 165 ? 139.701 136.838 68.950  1.00 32.23  ? 185 PHE A CB  1 
ATOM   1066  C CG  . PHE A 1 165 ? 138.618 136.013 69.594  1.00 31.27  ? 185 PHE A CG  1 
ATOM   1067  C CD1 . PHE A 1 165 ? 137.669 135.351 68.829  1.00 30.93  ? 185 PHE A CD1 1 
ATOM   1068  C CD2 . PHE A 1 165 ? 138.556 135.886 70.970  1.00 30.84  ? 185 PHE A CD2 1 
ATOM   1069  C CE1 . PHE A 1 165 ? 136.678 134.592 69.428  1.00 30.67  ? 185 PHE A CE1 1 
ATOM   1070  C CE2 . PHE A 1 165 ? 137.559 135.133 71.569  1.00 30.77  ? 185 PHE A CE2 1 
ATOM   1071  C CZ  . PHE A 1 165 ? 136.626 134.482 70.797  1.00 30.70  ? 185 PHE A CZ  1 
ATOM   1072  N N   . LYS A 1 166 ? 142.497 136.516 66.563  1.00 33.65  ? 186 LYS A N   1 
ATOM   1073  C CA  . LYS A 1 166 ? 143.688 137.195 66.081  1.00 34.96  ? 186 LYS A CA  1 
ATOM   1074  C C   . LYS A 1 166 ? 143.297 138.442 65.297  1.00 34.34  ? 186 LYS A C   1 
ATOM   1075  O O   . LYS A 1 166 ? 143.896 139.496 65.487  1.00 35.19  ? 186 LYS A O   1 
ATOM   1076  C CB  . LYS A 1 166 ? 144.530 136.255 65.217  1.00 37.06  ? 186 LYS A CB  1 
ATOM   1077  C CG  . LYS A 1 166 ? 145.859 136.824 64.742  1.00 38.86  ? 186 LYS A CG  1 
ATOM   1078  C CD  . LYS A 1 166 ? 146.601 135.888 63.821  1.00 40.85  ? 186 LYS A CD  1 
ATOM   1079  C CE  . LYS A 1 166 ? 147.827 136.513 63.193  1.00 42.44  ? 186 LYS A CE  1 
ATOM   1080  N NZ  . LYS A 1 166 ? 148.453 135.603 62.202  1.00 43.02  ? 186 LYS A NZ  1 
ATOM   1081  N N   . TYR A 1 167 ? 142.316 138.308 64.398  1.00 33.22  ? 187 TYR A N   1 
ATOM   1082  C CA  . TYR A 1 167 ? 141.916 139.405 63.535  1.00 32.74  ? 187 TYR A CA  1 
ATOM   1083  C C   . TYR A 1 167 ? 140.802 140.223 64.174  1.00 30.81  ? 187 TYR A C   1 
ATOM   1084  O O   . TYR A 1 167 ? 139.797 140.504 63.533  1.00 30.80  ? 187 TYR A O   1 
ATOM   1085  C CB  . TYR A 1 167 ? 141.482 138.871 62.170  1.00 34.27  ? 187 TYR A CB  1 
ATOM   1086  C CG  . TYR A 1 167 ? 142.622 138.364 61.329  1.00 36.74  ? 187 TYR A CG  1 
ATOM   1087  C CD1 . TYR A 1 167 ? 143.268 137.182 61.647  1.00 38.16  ? 187 TYR A CD1 1 
ATOM   1088  C CD2 . TYR A 1 167 ? 143.081 139.083 60.236  1.00 38.51  ? 187 TYR A CD2 1 
ATOM   1089  C CE1 . TYR A 1 167 ? 144.327 136.712 60.888  1.00 39.62  ? 187 TYR A CE1 1 
ATOM   1090  C CE2 . TYR A 1 167 ? 144.129 138.621 59.457  1.00 39.57  ? 187 TYR A CE2 1 
ATOM   1091  C CZ  . TYR A 1 167 ? 144.762 137.437 59.792  1.00 40.14  ? 187 TYR A CZ  1 
ATOM   1092  O OH  . TYR A 1 167 ? 145.800 136.970 59.024  1.00 41.06  ? 187 TYR A OH  1 
ATOM   1093  N N   . PHE A 1 168 ? 141.008 140.651 65.420  1.00 29.05  ? 188 PHE A N   1 
ATOM   1094  C CA  . PHE A 1 168 ? 140.005 141.445 66.104  1.00 27.85  ? 188 PHE A CA  1 
ATOM   1095  C C   . PHE A 1 168 ? 140.677 142.602 66.827  1.00 27.70  ? 188 PHE A C   1 
ATOM   1096  O O   . PHE A 1 168 ? 141.621 142.388 67.575  1.00 28.20  ? 188 PHE A O   1 
ATOM   1097  C CB  . PHE A 1 168 ? 139.225 140.592 67.102  1.00 27.49  ? 188 PHE A CB  1 
ATOM   1098  C CG  . PHE A 1 168 ? 138.100 141.335 67.774  1.00 27.06  ? 188 PHE A CG  1 
ATOM   1099  C CD1 . PHE A 1 168 ? 136.921 141.597 67.095  1.00 26.65  ? 188 PHE A CD1 1 
ATOM   1100  C CD2 . PHE A 1 168 ? 138.239 141.819 69.064  1.00 27.30  ? 188 PHE A CD2 1 
ATOM   1101  C CE1 . PHE A 1 168 ? 135.891 142.294 67.708  1.00 26.35  ? 188 PHE A CE1 1 
ATOM   1102  C CE2 . PHE A 1 168 ? 137.209 142.520 69.674  1.00 27.04  ? 188 PHE A CE2 1 
ATOM   1103  C CZ  . PHE A 1 168 ? 136.036 142.752 68.995  1.00 26.52  ? 188 PHE A CZ  1 
ATOM   1104  N N   . MET A 1 169 ? 140.176 143.817 66.605  1.00 27.76  ? 189 MET A N   1 
ATOM   1105  C CA  . MET A 1 169 ? 140.594 144.965 67.386  1.00 28.26  ? 189 MET A CA  1 
ATOM   1106  C C   . MET A 1 169 ? 139.355 145.725 67.825  1.00 27.25  ? 189 MET A C   1 
ATOM   1107  O O   . MET A 1 169 ? 138.279 145.538 67.270  1.00 27.86  ? 189 MET A O   1 
ATOM   1108  C CB  . MET A 1 169 ? 141.472 145.899 66.552  1.00 29.99  ? 189 MET A CB  1 
ATOM   1109  C CG  . MET A 1 169 ? 142.770 145.264 66.132  1.00 31.68  ? 189 MET A CG  1 
ATOM   1110  S SD  . MET A 1 169 ? 143.194 145.770 64.462  1.00 34.92  ? 189 MET A SD  1 
ATOM   1111  C CE  . MET A 1 169 ? 142.411 144.433 63.559  1.00 35.74  ? 189 MET A CE  1 
ATOM   1112  N N   . ARG A 1 170 ? 139.520 146.594 68.817  1.00 26.18  ? 190 ARG A N   1 
ATOM   1113  C CA  . ARG A 1 170 ? 138.428 147.444 69.241  1.00 25.71  ? 190 ARG A CA  1 
ATOM   1114  C C   . ARG A 1 170 ? 138.998 148.780 69.689  1.00 25.28  ? 190 ARG A C   1 
ATOM   1115  O O   . ARG A 1 170 ? 140.123 148.851 70.175  1.00 25.82  ? 190 ARG A O   1 
ATOM   1116  C CB  . ARG A 1 170 ? 137.615 146.767 70.345  1.00 25.93  ? 190 ARG A CB  1 
ATOM   1117  C CG  . ARG A 1 170 ? 138.459 146.117 71.426  1.00 26.22  ? 190 ARG A CG  1 
ATOM   1118  C CD  . ARG A 1 170 ? 137.577 145.519 72.493  1.00 26.45  ? 190 ARG A CD  1 
ATOM   1119  N NE  . ARG A 1 170 ? 138.322 144.677 73.411  1.00 27.34  ? 190 ARG A NE  1 
ATOM   1120  C CZ  . ARG A 1 170 ? 137.821 143.619 74.035  1.00 28.44  ? 190 ARG A CZ  1 
ATOM   1121  N NH1 . ARG A 1 170 ? 136.525 143.367 73.979  1.00 28.50  ? 190 ARG A NH1 1 
ATOM   1122  N NH2 . ARG A 1 170 ? 138.617 142.839 74.750  1.00 29.40  ? 190 ARG A NH2 1 
ATOM   1123  N N   . VAL A 1 171 ? 138.187 149.821 69.522  1.00 24.53  ? 191 VAL A N   1 
ATOM   1124  C CA  . VAL A 1 171 ? 138.577 151.178 69.848  1.00 24.13  ? 191 VAL A CA  1 
ATOM   1125  C C   . VAL A 1 171 ? 138.004 151.536 71.215  1.00 24.35  ? 191 VAL A C   1 
ATOM   1126  O O   . VAL A 1 171 ? 137.894 152.710 71.559  1.00 24.68  ? 191 VAL A O   1 
ATOM   1127  C CB  . VAL A 1 171 ? 138.108 152.143 68.746  1.00 24.08  ? 191 VAL A CB  1 
ATOM   1128  C CG1 . VAL A 1 171 ? 138.909 151.956 67.471  1.00 24.16  ? 191 VAL A CG1 1 
ATOM   1129  C CG2 . VAL A 1 171 ? 136.624 151.997 68.464  1.00 24.28  ? 191 VAL A CG2 1 
ATOM   1130  N N   . VAL A 1 172 ? 137.670 150.505 71.996  1.00 24.86  ? 192 VAL A N   1 
ATOM   1131  C CA  . VAL A 1 172 ? 137.134 150.679 73.333  1.00 25.53  ? 192 VAL A CA  1 
ATOM   1132  C C   . VAL A 1 172 ? 137.901 149.766 74.279  1.00 26.33  ? 192 VAL A C   1 
ATOM   1133  O O   . VAL A 1 172 ? 138.366 148.705 73.875  1.00 26.63  ? 192 VAL A O   1 
ATOM   1134  C CB  . VAL A 1 172 ? 135.627 150.369 73.373  1.00 25.81  ? 192 VAL A CB  1 
ATOM   1135  C CG1 . VAL A 1 172 ? 134.807 151.516 72.811  1.00 26.12  ? 192 VAL A CG1 1 
ATOM   1136  C CG2 . VAL A 1 172 ? 135.285 149.064 72.667  1.00 25.65  ? 192 VAL A CG2 1 
ATOM   1137  N N   . PRO A 1 173 ? 138.052 150.131 75.569  1.00 27.80  ? 193 PRO A N   1 
ATOM   1138  C CA  . PRO A 1 173 ? 138.681 149.234 76.535  1.00 28.85  ? 193 PRO A CA  1 
ATOM   1139  C C   . PRO A 1 173 ? 137.797 148.024 76.829  1.00 29.89  ? 193 PRO A C   1 
ATOM   1140  O O   . PRO A 1 173 ? 136.598 148.043 76.555  1.00 29.99  ? 193 PRO A O   1 
ATOM   1141  C CB  . PRO A 1 173 ? 138.865 150.116 77.778  1.00 29.06  ? 193 PRO A CB  1 
ATOM   1142  C CG  . PRO A 1 173 ? 137.788 151.171 77.651  1.00 28.87  ? 193 PRO A CG  1 
ATOM   1143  C CD  . PRO A 1 173 ? 137.645 151.415 76.161  1.00 28.42  ? 193 PRO A CD  1 
ATOM   1144  N N   . SER A 1 174 ? 138.405 146.971 77.386  1.00 31.55  ? 194 SER A N   1 
ATOM   1145  C CA  . SER A 1 174 ? 137.673 145.774 77.769  1.00 33.11  ? 194 SER A CA  1 
ATOM   1146  C C   . SER A 1 174 ? 136.829 146.060 79.008  1.00 34.36  ? 194 SER A C   1 
ATOM   1147  O O   . SER A 1 174 ? 136.922 147.130 79.603  1.00 34.78  ? 194 SER A O   1 
ATOM   1148  C CB  . SER A 1 174 ? 138.598 144.619 78.013  1.00 33.91  ? 194 SER A CB  1 
ATOM   1149  O OG  . SER A 1 174 ? 139.476 144.910 79.086  1.00 34.62  ? 194 SER A OG  1 
ATOM   1150  N N   . ASP A 1 175 ? 135.983 145.100 79.389  1.00 36.16  ? 195 ASP A N   1 
ATOM   1151  C CA  . ASP A 1 175 ? 135.076 145.299 80.508  1.00 38.00  ? 195 ASP A CA  1 
ATOM   1152  C C   . ASP A 1 175 ? 135.762 144.934 81.827  1.00 38.73  ? 195 ASP A C   1 
ATOM   1153  O O   . ASP A 1 175 ? 135.116 144.972 82.869  1.00 39.44  ? 195 ASP A O   1 
ATOM   1154  C CB  . ASP A 1 175 ? 133.764 144.536 80.312  1.00 39.41  ? 195 ASP A CB  1 
ATOM   1155  C CG  . ASP A 1 175 ? 133.958 143.042 80.144  1.00 41.94  ? 195 ASP A CG  1 
ATOM   1156  O OD1 . ASP A 1 175 ? 135.127 142.613 80.124  1.00 42.93  ? 195 ASP A OD1 1 
ATOM   1157  O OD2 . ASP A 1 175 ? 132.948 142.327 80.015  1.00 42.55  ? 195 ASP A OD2 1 
ATOM   1158  N N   . ALA A 1 176 ? 137.062 144.617 81.804  1.00 38.65  ? 196 ALA A N   1 
ATOM   1159  C CA  . ALA A 1 176 ? 137.841 144.512 83.030  1.00 39.25  ? 196 ALA A CA  1 
ATOM   1160  C C   . ALA A 1 176 ? 137.821 145.848 83.769  1.00 39.10  ? 196 ALA A C   1 
ATOM   1161  O O   . ALA A 1 176 ? 137.607 145.895 84.981  1.00 39.74  ? 196 ALA A O   1 
ATOM   1162  C CB  . ALA A 1 176 ? 139.254 144.088 82.717  1.00 39.57  ? 196 ALA A CB  1 
ATOM   1163  N N   . GLN A 1 177 ? 138.036 146.934 83.022  1.00 38.56  ? 197 GLN A N   1 
ATOM   1164  C CA  . GLN A 1 177 ? 138.065 148.264 83.604  1.00 38.66  ? 197 GLN A CA  1 
ATOM   1165  C C   . GLN A 1 177 ? 136.672 148.638 84.100  1.00 37.58  ? 197 GLN A C   1 
ATOM   1166  O O   . GLN A 1 177 ? 136.541 149.285 85.135  1.00 38.24  ? 197 GLN A O   1 
ATOM   1167  C CB  . GLN A 1 177 ? 138.593 149.284 82.598  1.00 39.61  ? 197 GLN A CB  1 
ATOM   1168  C CG  . GLN A 1 177 ? 139.995 148.967 82.102  1.00 40.73  ? 197 GLN A CG  1 
ATOM   1169  C CD  . GLN A 1 177 ? 140.599 150.099 81.307  1.00 42.15  ? 197 GLN A CD  1 
ATOM   1170  O OE1 . GLN A 1 177 ? 140.104 151.225 81.308  1.00 42.89  ? 197 GLN A OE1 1 
ATOM   1171  N NE2 . GLN A 1 177 ? 141.692 149.805 80.622  1.00 42.92  ? 197 GLN A NE2 1 
ATOM   1172  N N   . GLN A 1 178 ? 135.635 148.208 83.377  1.00 36.57  ? 198 GLN A N   1 
ATOM   1173  C CA  . GLN A 1 178 ? 134.271 148.511 83.769  1.00 36.30  ? 198 GLN A CA  1 
ATOM   1174  C C   . GLN A 1 178 ? 133.910 147.766 85.056  1.00 35.85  ? 198 GLN A C   1 
ATOM   1175  O O   . GLN A 1 178 ? 133.231 148.319 85.915  1.00 36.15  ? 198 GLN A O   1 
ATOM   1176  C CB  . GLN A 1 178 ? 133.312 148.176 82.630  1.00 36.84  ? 198 GLN A CB  1 
ATOM   1177  C CG  . GLN A 1 178 ? 131.877 148.586 82.921  1.00 37.16  ? 198 GLN A CG  1 
ATOM   1178  C CD  . GLN A 1 178 ? 131.034 148.629 81.677  1.00 37.72  ? 198 GLN A CD  1 
ATOM   1179  O OE1 . GLN A 1 178 ? 130.180 149.501 81.519  1.00 38.00  ? 198 GLN A OE1 1 
ATOM   1180  N NE2 . GLN A 1 178 ? 131.242 147.658 80.802  1.00 38.45  ? 198 GLN A NE2 1 
ATOM   1181  N N   . ALA A 1 179 ? 134.354 146.513 85.191  1.00 36.28  ? 199 ALA A N   1 
ATOM   1182  C CA  . ALA A 1 179 ? 134.104 145.753 86.405  1.00 37.27  ? 199 ALA A CA  1 
ATOM   1183  C C   . ALA A 1 179 ? 134.817 146.410 87.583  1.00 38.65  ? 199 ALA A C   1 
ATOM   1184  O O   . ALA A 1 179 ? 134.263 146.478 88.681  1.00 39.62  ? 199 ALA A O   1 
ATOM   1185  C CB  . ALA A 1 179 ? 134.549 144.326 86.231  1.00 37.17  ? 199 ALA A CB  1 
ATOM   1186  N N   . ARG A 1 180 ? 136.042 146.895 87.344  1.00 39.24  ? 200 ARG A N   1 
ATOM   1187  C CA  . ARG A 1 180 ? 136.798 147.605 88.363  1.00 39.64  ? 200 ARG A CA  1 
ATOM   1188  C C   . ARG A 1 180 ? 136.045 148.871 88.771  1.00 38.96  ? 200 ARG A C   1 
ATOM   1189  O O   . ARG A 1 180 ? 135.979 149.193 89.956  1.00 40.09  ? 200 ARG A O   1 
ATOM   1190  C CB  . ARG A 1 180 ? 138.211 147.928 87.869  1.00 41.66  ? 200 ARG A CB  1 
ATOM   1191  C CG  . ARG A 1 180 ? 139.254 146.856 88.150  1.00 44.25  ? 200 ARG A CG  1 
ATOM   1192  C CD  . ARG A 1 180 ? 140.182 147.209 89.300  1.00 46.48  ? 200 ARG A CD  1 
ATOM   1193  N NE  . ARG A 1 180 ? 139.503 147.355 90.581  1.00 48.00  ? 200 ARG A NE  1 
ATOM   1194  C CZ  . ARG A 1 180 ? 139.399 146.397 91.497  1.00 49.77  ? 200 ARG A CZ  1 
ATOM   1195  N NH1 . ARG A 1 180 ? 139.810 145.168 91.230  1.00 50.21  ? 200 ARG A NH1 1 
ATOM   1196  N NH2 . ARG A 1 180 ? 138.845 146.663 92.668  1.00 49.91  ? 200 ARG A NH2 1 
ATOM   1197  N N   . ALA A 1 181 ? 135.468 149.577 87.793  1.00 37.49  ? 201 ALA A N   1 
ATOM   1198  C CA  . ALA A 1 181 ? 134.732 150.798 88.076  1.00 36.80  ? 201 ALA A CA  1 
ATOM   1199  C C   . ALA A 1 181 ? 133.519 150.491 88.949  1.00 36.94  ? 201 ALA A C   1 
ATOM   1200  O O   . ALA A 1 181 ? 133.246 151.216 89.904  1.00 37.98  ? 201 ALA A O   1 
ATOM   1201  C CB  . ALA A 1 181 ? 134.330 151.482 86.795  1.00 36.65  ? 201 ALA A CB  1 
ATOM   1202  N N   . MET A 1 182 ? 132.800 149.412 88.622  1.00 37.45  ? 202 MET A N   1 
ATOM   1203  C CA  . MET A 1 182 ? 131.592 149.061 89.350  1.00 38.65  ? 202 MET A CA  1 
ATOM   1204  C C   . MET A 1 182 ? 131.955 148.702 90.787  1.00 39.77  ? 202 MET A C   1 
ATOM   1205  O O   . MET A 1 182 ? 131.264 149.114 91.714  1.00 40.42  ? 202 MET A O   1 
ATOM   1206  C CB  . MET A 1 182 ? 130.850 147.884 88.706  1.00 39.08  ? 202 MET A CB  1 
ATOM   1207  C CG  . MET A 1 182 ? 130.238 148.223 87.358  1.00 39.68  ? 202 MET A CG  1 
ATOM   1208  S SD  . MET A 1 182 ? 128.847 147.173 86.840  1.00 41.52  ? 202 MET A SD  1 
ATOM   1209  C CE  . MET A 1 182 ? 129.077 145.707 87.842  1.00 41.91  ? 202 MET A CE  1 
ATOM   1210  N N   . VAL A 1 183 ? 133.047 147.952 90.971  1.00 40.35  ? 203 VAL A N   1 
ATOM   1211  C CA  . VAL A 1 183 ? 133.425 147.524 92.308  1.00 40.93  ? 203 VAL A CA  1 
ATOM   1212  C C   . VAL A 1 183 ? 133.902 148.729 93.116  1.00 41.34  ? 203 VAL A C   1 
ATOM   1213  O O   . VAL A 1 183 ? 133.639 148.790 94.314  1.00 42.82  ? 203 VAL A O   1 
ATOM   1214  C CB  . VAL A 1 183 ? 134.454 146.380 92.302  1.00 41.62  ? 203 VAL A CB  1 
ATOM   1215  C CG1 . VAL A 1 183 ? 135.799 146.818 91.771  1.00 42.10  ? 203 VAL A CG1 1 
ATOM   1216  C CG2 . VAL A 1 183 ? 134.617 145.771 93.684  1.00 42.48  ? 203 VAL A CG2 1 
ATOM   1217  N N   . ASP A 1 184 ? 134.575 149.690 92.472  1.00 40.92  ? 204 ASP A N   1 
ATOM   1218  C CA  . ASP A 1 184 ? 134.989 150.901 93.164  1.00 41.49  ? 204 ASP A CA  1 
ATOM   1219  C C   . ASP A 1 184 ? 133.766 151.693 93.624  1.00 41.64  ? 204 ASP A C   1 
ATOM   1220  O O   . ASP A 1 184 ? 133.752 152.210 94.737  1.00 42.81  ? 204 ASP A O   1 
ATOM   1221  C CB  . ASP A 1 184 ? 135.912 151.759 92.300  1.00 42.58  ? 204 ASP A CB  1 
ATOM   1222  C CG  . ASP A 1 184 ? 137.256 151.107 92.037  1.00 44.52  ? 204 ASP A CG  1 
ATOM   1223  O OD1 . ASP A 1 184 ? 137.476 149.985 92.543  1.00 45.62  ? 204 ASP A OD1 1 
ATOM   1224  O OD2 . ASP A 1 184 ? 138.063 151.714 91.313  1.00 44.91  ? 204 ASP A OD2 1 
ATOM   1225  N N   . ILE A 1 185 ? 132.742 151.787 92.770  1.00 41.31  ? 205 ILE A N   1 
ATOM   1226  C CA  . ILE A 1 185 ? 131.535 152.519 93.122  1.00 41.31  ? 205 ILE A CA  1 
ATOM   1227  C C   . ILE A 1 185 ? 130.840 151.822 94.289  1.00 42.36  ? 205 ILE A C   1 
ATOM   1228  O O   . ILE A 1 185 ? 130.354 152.487 95.197  1.00 43.99  ? 205 ILE A O   1 
ATOM   1229  C CB  . ILE A 1 185 ? 130.598 152.685 91.910  1.00 40.98  ? 205 ILE A CB  1 
ATOM   1230  C CG1 . ILE A 1 185 ? 131.267 153.513 90.810  1.00 41.24  ? 205 ILE A CG1 1 
ATOM   1231  C CG2 . ILE A 1 185 ? 129.262 153.285 92.329  1.00 40.59  ? 205 ILE A CG2 1 
ATOM   1232  C CD1 . ILE A 1 185 ? 130.540 153.493 89.490  1.00 41.36  ? 205 ILE A CD1 1 
ATOM   1233  N N   . VAL A 1 186 ? 130.787 150.487 94.259  1.00 43.11  ? 206 VAL A N   1 
ATOM   1234  C CA  . VAL A 1 186 ? 130.121 149.724 95.302  1.00 44.60  ? 206 VAL A CA  1 
ATOM   1235  C C   . VAL A 1 186 ? 130.853 149.897 96.632  1.00 46.89  ? 206 VAL A C   1 
ATOM   1236  O O   . VAL A 1 186 ? 130.219 150.034 97.675  1.00 48.29  ? 206 VAL A O   1 
ATOM   1237  C CB  . VAL A 1 186 ? 130.016 148.236 94.913  1.00 45.27  ? 206 VAL A CB  1 
ATOM   1238  C CG1 . VAL A 1 186 ? 129.751 147.335 96.106  1.00 45.96  ? 206 VAL A CG1 1 
ATOM   1239  C CG2 . VAL A 1 186 ? 128.963 148.017 93.840  1.00 45.71  ? 206 VAL A CG2 1 
ATOM   1240  N N   . LYS A 1 187 ? 132.189 149.871 96.599  1.00 49.15  ? 207 LYS A N   1 
ATOM   1241  C CA  . LYS A 1 187 ? 132.961 149.926 97.828  1.00 51.39  ? 207 LYS A CA  1 
ATOM   1242  C C   . LYS A 1 187 ? 132.987 151.350 98.383  1.00 52.55  ? 207 LYS A C   1 
ATOM   1243  O O   . LYS A 1 187 ? 133.145 151.521 99.588  1.00 53.91  ? 207 LYS A O   1 
ATOM   1244  C CB  . LYS A 1 187 ? 134.389 149.419 97.618  1.00 53.11  ? 207 LYS A CB  1 
ATOM   1245  C CG  . LYS A 1 187 ? 135.352 150.416 96.986  1.00 55.25  ? 207 LYS A CG  1 
ATOM   1246  C CD  . LYS A 1 187 ? 136.812 150.089 97.236  1.00 57.37  ? 207 LYS A CD  1 
ATOM   1247  C CE  . LYS A 1 187 ? 137.210 148.689 96.811  1.00 59.08  ? 207 LYS A CE  1 
ATOM   1248  N NZ  . LYS A 1 187 ? 138.600 148.370 97.212  1.00 59.86  ? 207 LYS A NZ  1 
ATOM   1249  N N   . ARG A 1 188 ? 132.842 152.365 97.519  1.00 52.25  ? 208 ARG A N   1 
ATOM   1250  C CA  . ARG A 1 188 ? 132.870 153.754 97.961  1.00 52.91  ? 208 ARG A CA  1 
ATOM   1251  C C   . ARG A 1 188 ? 131.689 154.043 98.887  1.00 54.02  ? 208 ARG A C   1 
ATOM   1252  O O   . ARG A 1 188 ? 131.813 154.856 99.801  1.00 55.50  ? 208 ARG A O   1 
ATOM   1253  C CB  . ARG A 1 188 ? 132.875 154.716 96.768  1.00 53.02  ? 208 ARG A CB  1 
ATOM   1254  C CG  . ARG A 1 188 ? 132.625 156.173 97.131  1.00 54.33  ? 208 ARG A CG  1 
ATOM   1255  C CD  . ARG A 1 188 ? 132.875 157.121 95.980  1.00 55.89  ? 208 ARG A CD  1 
ATOM   1256  N NE  . ARG A 1 188 ? 134.284 157.478 95.866  1.00 57.44  ? 208 ARG A NE  1 
ATOM   1257  C CZ  . ARG A 1 188 ? 134.757 158.723 95.834  1.00 58.93  ? 208 ARG A CZ  1 
ATOM   1258  N NH1 . ARG A 1 188 ? 133.936 159.758 95.885  1.00 59.01  ? 208 ARG A NH1 1 
ATOM   1259  N NH2 . ARG A 1 188 ? 136.060 158.932 95.745  1.00 59.64  ? 208 ARG A NH2 1 
ATOM   1260  N N   . TYR A 1 189 ? 130.548 153.382 98.649  1.00 54.69  ? 209 TYR A N   1 
ATOM   1261  C CA  . TYR A 1 189 ? 129.374 153.560 99.492  1.00 56.15  ? 209 TYR A CA  1 
ATOM   1262  C C   . TYR A 1 189 ? 129.173 152.377 100.438 1.00 59.25  ? 209 TYR A C   1 
ATOM   1263  O O   . TYR A 1 189 ? 128.097 152.229 101.015 1.00 58.93  ? 209 TYR A O   1 
ATOM   1264  C CB  . TYR A 1 189 ? 128.131 153.775 98.631  1.00 55.51  ? 209 TYR A CB  1 
ATOM   1265  C CG  . TYR A 1 189 ? 128.326 154.751 97.504  1.00 56.10  ? 209 TYR A CG  1 
ATOM   1266  C CD1 . TYR A 1 189 ? 129.040 155.923 97.688  1.00 57.11  ? 209 TYR A CD1 1 
ATOM   1267  C CD2 . TYR A 1 189 ? 127.814 154.492 96.248  1.00 57.50  ? 209 TYR A CD2 1 
ATOM   1268  C CE1 . TYR A 1 189 ? 129.228 156.822 96.653  1.00 57.98  ? 209 TYR A CE1 1 
ATOM   1269  C CE2 . TYR A 1 189 ? 127.992 155.379 95.198  1.00 58.30  ? 209 TYR A CE2 1 
ATOM   1270  C CZ  . TYR A 1 189 ? 128.699 156.551 95.405  1.00 58.24  ? 209 TYR A CZ  1 
ATOM   1271  O OH  . TYR A 1 189 ? 128.887 157.445 94.381  1.00 58.67  ? 209 TYR A OH  1 
ATOM   1272  N N   . ASN A 1 190 ? 130.213 151.551 100.604 1.00 63.35  ? 210 ASN A N   1 
ATOM   1273  C CA  . ASN A 1 190 ? 130.256 150.529 101.640 1.00 67.81  ? 210 ASN A CA  1 
ATOM   1274  C C   . ASN A 1 190 ? 129.098 149.550 101.455 1.00 65.09  ? 210 ASN A C   1 
ATOM   1275  O O   . ASN A 1 190 ? 128.632 148.948 102.423 1.00 66.70  ? 210 ASN A O   1 
ATOM   1276  C CB  . ASN A 1 190 ? 130.275 151.157 103.039 1.00 74.25  ? 210 ASN A CB  1 
ATOM   1277  C CG  . ASN A 1 190 ? 131.101 152.428 103.088 1.00 81.76  ? 210 ASN A CG  1 
ATOM   1278  O OD1 . ASN A 1 190 ? 132.183 152.483 102.504 1.00 82.09  ? 210 ASN A OD1 1 
ATOM   1279  N ND2 . ASN A 1 190 ? 130.600 153.460 103.753 1.00 90.97  ? 210 ASN A ND2 1 
ATOM   1280  N N   . TRP A 1 191 ? 128.646 149.395 100.207 1.00 60.99  ? 211 TRP A N   1 
ATOM   1281  C CA  . TRP A 1 191 ? 127.667 148.377 99.880  1.00 58.37  ? 211 TRP A CA  1 
ATOM   1282  C C   . TRP A 1 191 ? 128.314 147.002 99.991  1.00 56.61  ? 211 TRP A C   1 
ATOM   1283  O O   . TRP A 1 191 ? 129.256 146.693 99.270  1.00 57.07  ? 211 TRP A O   1 
ATOM   1284  C CB  . TRP A 1 191 ? 127.076 148.616 98.490  1.00 57.89  ? 211 TRP A CB  1 
ATOM   1285  C CG  . TRP A 1 191 ? 126.234 149.851 98.403  1.00 58.19  ? 211 TRP A CG  1 
ATOM   1286  C CD1 . TRP A 1 191 ? 125.465 150.400 99.388  1.00 59.21  ? 211 TRP A CD1 1 
ATOM   1287  C CD2 . TRP A 1 191 ? 126.050 150.676 97.242  1.00 57.56  ? 211 TRP A CD2 1 
ATOM   1288  N NE1 . TRP A 1 191 ? 124.827 151.518 98.922  1.00 58.64  ? 211 TRP A NE1 1 
ATOM   1289  C CE2 . TRP A 1 191 ? 125.166 151.711 97.609  1.00 57.73  ? 211 TRP A CE2 1 
ATOM   1290  C CE3 . TRP A 1 191 ? 126.555 150.648 95.938  1.00 57.38  ? 211 TRP A CE3 1 
ATOM   1291  C CZ2 . TRP A 1 191 ? 124.777 152.703 96.713  1.00 58.13  ? 211 TRP A CZ2 1 
ATOM   1292  C CZ3 . TRP A 1 191 ? 126.162 151.622 95.049  1.00 57.53  ? 211 TRP A CZ3 1 
ATOM   1293  C CH2 . TRP A 1 191 ? 125.282 152.633 95.433  1.00 58.08  ? 211 TRP A CH2 1 
ATOM   1294  N N   . THR A 1 192 ? 127.786 146.179 100.897 1.00 55.45  ? 212 THR A N   1 
ATOM   1295  C CA  . THR A 1 192 ? 128.371 144.884 101.196 1.00 55.06  ? 212 THR A CA  1 
ATOM   1296  C C   . THR A 1 192 ? 127.529 143.762 100.595 1.00 51.34  ? 212 THR A C   1 
ATOM   1297  O O   . THR A 1 192 ? 128.061 142.845 99.989  1.00 51.53  ? 212 THR A O   1 
ATOM   1298  C CB  . THR A 1 192 ? 128.531 144.727 102.713 1.00 59.04  ? 212 THR A CB  1 
ATOM   1299  O OG1 . THR A 1 192 ? 129.686 145.471 103.104 1.00 60.55  ? 212 THR A OG1 1 
ATOM   1300  C CG2 . THR A 1 192 ? 128.672 143.290 103.165 1.00 60.37  ? 212 THR A CG2 1 
ATOM   1301  N N   . TYR A 1 193 ? 126.219 143.811 100.822 1.00 49.66  ? 213 TYR A N   1 
ATOM   1302  C CA  . TYR A 1 193 ? 125.325 142.735 100.434 1.00 49.19  ? 213 TYR A CA  1 
ATOM   1303  C C   . TYR A 1 193 ? 124.494 143.178 99.237  1.00 48.42  ? 213 TYR A C   1 
ATOM   1304  O O   . TYR A 1 193 ? 123.386 143.681 99.398  1.00 49.49  ? 213 TYR A O   1 
ATOM   1305  C CB  . TYR A 1 193 ? 124.446 142.347 101.621 1.00 49.76  ? 213 TYR A CB  1 
ATOM   1306  C CG  . TYR A 1 193 ? 123.668 141.067 101.457 1.00 50.01  ? 213 TYR A CG  1 
ATOM   1307  C CD1 . TYR A 1 193 ? 124.312 139.845 101.340 1.00 50.34  ? 213 TYR A CD1 1 
ATOM   1308  C CD2 . TYR A 1 193 ? 122.283 141.079 101.440 1.00 51.45  ? 213 TYR A CD2 1 
ATOM   1309  C CE1 . TYR A 1 193 ? 123.599 138.664 101.217 1.00 51.34  ? 213 TYR A CE1 1 
ATOM   1310  C CE2 . TYR A 1 193 ? 121.554 139.907 101.308 1.00 52.25  ? 213 TYR A CE2 1 
ATOM   1311  C CZ  . TYR A 1 193 ? 122.215 138.695 101.201 1.00 52.43  ? 213 TYR A CZ  1 
ATOM   1312  O OH  . TYR A 1 193 ? 121.500 137.530 101.059 1.00 53.03  ? 213 TYR A OH  1 
ATOM   1313  N N   . VAL A 1 194 ? 125.035 142.966 98.032  1.00 45.88  ? 214 VAL A N   1 
ATOM   1314  C CA  . VAL A 1 194 ? 124.351 143.350 96.805  1.00 43.10  ? 214 VAL A CA  1 
ATOM   1315  C C   . VAL A 1 194 ? 123.833 142.097 96.105  1.00 42.11  ? 214 VAL A C   1 
ATOM   1316  O O   . VAL A 1 194 ? 124.284 140.989 96.385  1.00 42.52  ? 214 VAL A O   1 
ATOM   1317  C CB  . VAL A 1 194 ? 125.267 144.166 95.874  1.00 41.40  ? 214 VAL A CB  1 
ATOM   1318  C CG1 . VAL A 1 194 ? 125.743 145.444 96.545  1.00 41.11  ? 214 VAL A CG1 1 
ATOM   1319  C CG2 . VAL A 1 194 ? 126.447 143.354 95.369  1.00 41.36  ? 214 VAL A CG2 1 
ATOM   1320  N N   . SER A 1 195 ? 122.876 142.305 95.196  1.00 40.77  ? 215 SER A N   1 
ATOM   1321  C CA  . SER A 1 195 ? 122.374 141.256 94.326  1.00 40.17  ? 215 SER A CA  1 
ATOM   1322  C C   . SER A 1 195 ? 122.847 141.532 92.903  1.00 39.51  ? 215 SER A C   1 
ATOM   1323  O O   . SER A 1 195 ? 122.890 142.686 92.487  1.00 40.30  ? 215 SER A O   1 
ATOM   1324  C CB  . SER A 1 195 ? 120.880 141.190 94.405  1.00 40.40  ? 215 SER A CB  1 
ATOM   1325  O OG  . SER A 1 195 ? 120.399 140.054 93.715  1.00 41.09  ? 215 SER A OG  1 
ATOM   1326  N N   . ALA A 1 196 ? 123.223 140.478 92.172  1.00 38.13  ? 216 ALA A N   1 
ATOM   1327  C CA  . ALA A 1 196 ? 123.841 140.642 90.864  1.00 36.84  ? 216 ALA A CA  1 
ATOM   1328  C C   . ALA A 1 196 ? 122.936 140.064 89.781  1.00 35.20  ? 216 ALA A C   1 
ATOM   1329  O O   . ALA A 1 196 ? 122.403 138.968 89.929  1.00 36.07  ? 216 ALA A O   1 
ATOM   1330  C CB  . ALA A 1 196 ? 125.199 139.983 90.851  1.00 37.29  ? 216 ALA A CB  1 
ATOM   1331  N N   . VAL A 1 197 ? 122.770 140.822 88.693  1.00 33.58  ? 217 VAL A N   1 
ATOM   1332  C CA  . VAL A 1 197 ? 122.063 140.360 87.509  1.00 32.43  ? 217 VAL A CA  1 
ATOM   1333  C C   . VAL A 1 197 ? 122.960 140.625 86.307  1.00 32.27  ? 217 VAL A C   1 
ATOM   1334  O O   . VAL A 1 197 ? 123.568 141.688 86.218  1.00 32.76  ? 217 VAL A O   1 
ATOM   1335  C CB  . VAL A 1 197 ? 120.708 141.074 87.348  1.00 31.71  ? 217 VAL A CB  1 
ATOM   1336  C CG1 . VAL A 1 197 ? 120.033 140.734 86.028  1.00 31.27  ? 217 VAL A CG1 1 
ATOM   1337  C CG2 . VAL A 1 197 ? 119.779 140.784 88.515  1.00 32.09  ? 217 VAL A CG2 1 
ATOM   1338  N N   . HIS A 1 198 ? 123.030 139.664 85.382  1.00 31.90  ? 218 HIS A N   1 
ATOM   1339  C CA  . HIS A 1 198 ? 123.784 139.858 84.154  1.00 31.66  ? 218 HIS A CA  1 
ATOM   1340  C C   . HIS A 1 198 ? 123.038 139.198 83.005  1.00 31.13  ? 218 HIS A C   1 
ATOM   1341  O O   . HIS A 1 198 ? 122.416 138.154 83.186  1.00 32.08  ? 218 HIS A O   1 
ATOM   1342  C CB  . HIS A 1 198 ? 125.206 139.304 84.284  1.00 31.92  ? 218 HIS A CB  1 
ATOM   1343  C CG  . HIS A 1 198 ? 125.287 137.815 84.289  1.00 31.83  ? 218 HIS A CG  1 
ATOM   1344  N ND1 . HIS A 1 198 ? 125.299 137.062 83.136  1.00 31.78  ? 218 HIS A ND1 1 
ATOM   1345  C CD2 . HIS A 1 198 ? 125.396 136.949 85.303  1.00 32.29  ? 218 HIS A CD2 1 
ATOM   1346  C CE1 . HIS A 1 198 ? 125.398 135.781 83.457  1.00 32.21  ? 218 HIS A CE1 1 
ATOM   1347  N NE2 . HIS A 1 198 ? 125.462 135.691 84.767  1.00 32.47  ? 218 HIS A NE2 1 
ATOM   1348  N N   . THR A 1 199 ? 123.124 139.811 81.821  1.00 31.14  ? 219 THR A N   1 
ATOM   1349  C CA  . THR A 1 199 ? 122.460 139.276 80.647  1.00 31.67  ? 219 THR A CA  1 
ATOM   1350  C C   . THR A 1 199 ? 123.181 138.017 80.184  1.00 33.23  ? 219 THR A C   1 
ATOM   1351  O O   . THR A 1 199 ? 124.409 137.958 80.211  1.00 34.03  ? 219 THR A O   1 
ATOM   1352  C CB  . THR A 1 199 ? 122.414 140.301 79.510  1.00 31.66  ? 219 THR A CB  1 
ATOM   1353  O OG1 . THR A 1 199 ? 121.811 141.486 80.025  1.00 32.07  ? 219 THR A OG1 1 
ATOM   1354  C CG2 . THR A 1 199 ? 121.637 139.807 78.309  1.00 31.83  ? 219 THR A CG2 1 
ATOM   1355  N N   . GLU A 1 200 ? 122.403 137.019 79.752  1.00 35.38  ? 220 GLU A N   1 
ATOM   1356  C CA  . GLU A 1 200 ? 122.964 135.819 79.157  1.00 37.16  ? 220 GLU A CA  1 
ATOM   1357  C C   . GLU A 1 200 ? 123.728 136.212 77.899  1.00 37.46  ? 220 GLU A C   1 
ATOM   1358  O O   . GLU A 1 200 ? 123.233 137.002 77.097  1.00 37.96  ? 220 GLU A O   1 
ATOM   1359  C CB  . GLU A 1 200 ? 121.857 134.823 78.814  1.00 39.35  ? 220 GLU A CB  1 
ATOM   1360  C CG  . GLU A 1 200 ? 121.445 133.951 79.983  1.00 41.69  ? 220 GLU A CG  1 
ATOM   1361  C CD  . GLU A 1 200 ? 122.276 132.688 80.127  1.00 44.28  ? 220 GLU A CD  1 
ATOM   1362  O OE1 . GLU A 1 200 ? 123.511 132.772 79.961  1.00 45.51  ? 220 GLU A OE1 1 
ATOM   1363  O OE2 . GLU A 1 200 ? 121.689 131.625 80.427  1.00 44.89  ? 220 GLU A OE2 1 
ATOM   1364  N N   . GLY A 1 201 ? 124.926 135.649 77.728  1.00 37.35  ? 221 GLY A N   1 
ATOM   1365  C CA  . GLY A 1 201 ? 125.742 135.965 76.570  1.00 37.43  ? 221 GLY A CA  1 
ATOM   1366  C C   . GLY A 1 201 ? 127.222 135.922 76.916  1.00 36.92  ? 221 GLY A C   1 
ATOM   1367  O O   . GLY A 1 201 ? 127.657 135.024 77.624  1.00 37.51  ? 221 GLY A O   1 
ATOM   1368  N N   . ASN A 1 202 ? 127.982 136.887 76.395  1.00 35.96  ? 222 ASN A N   1 
ATOM   1369  C CA  . ASN A 1 202 ? 129.413 136.943 76.635  1.00 35.11  ? 222 ASN A CA  1 
ATOM   1370  C C   . ASN A 1 202 ? 129.772 138.230 77.373  1.00 34.22  ? 222 ASN A C   1 
ATOM   1371  O O   . ASN A 1 202 ? 130.643 138.232 78.235  1.00 34.58  ? 222 ASN A O   1 
ATOM   1372  C CB  . ASN A 1 202 ? 130.214 136.835 75.338  1.00 35.45  ? 222 ASN A CB  1 
ATOM   1373  C CG  . ASN A 1 202 ? 131.647 136.439 75.616  1.00 36.07  ? 222 ASN A CG  1 
ATOM   1374  O OD1 . ASN A 1 202 ? 132.581 137.202 75.374  1.00 36.15  ? 222 ASN A OD1 1 
ATOM   1375  N ND2 . ASN A 1 202 ? 131.823 135.236 76.136  1.00 36.35  ? 222 ASN A ND2 1 
ATOM   1376  N N   . TYR A 1 203 ? 129.147 139.341 76.980  1.00 33.64  ? 223 TYR A N   1 
ATOM   1377  C CA  . TYR A 1 203 ? 129.330 140.611 77.662  1.00 33.25  ? 223 TYR A CA  1 
ATOM   1378  C C   . TYR A 1 203 ? 128.950 140.459 79.131  1.00 33.40  ? 223 TYR A C   1 
ATOM   1379  O O   . TYR A 1 203 ? 129.748 140.745 80.019  1.00 33.72  ? 223 TYR A O   1 
ATOM   1380  C CB  . TYR A 1 203 ? 128.483 141.685 76.982  1.00 33.40  ? 223 TYR A CB  1 
ATOM   1381  C CG  . TYR A 1 203 ? 128.361 142.971 77.753  1.00 33.87  ? 223 TYR A CG  1 
ATOM   1382  C CD1 . TYR A 1 203 ? 129.477 143.740 78.032  1.00 34.55  ? 223 TYR A CD1 1 
ATOM   1383  C CD2 . TYR A 1 203 ? 127.131 143.426 78.198  1.00 33.92  ? 223 TYR A CD2 1 
ATOM   1384  C CE1 . TYR A 1 203 ? 129.373 144.942 78.714  1.00 34.68  ? 223 TYR A CE1 1 
ATOM   1385  C CE2 . TYR A 1 203 ? 127.011 144.619 78.889  1.00 33.83  ? 223 TYR A CE2 1 
ATOM   1386  C CZ  . TYR A 1 203 ? 128.137 145.377 79.153  1.00 34.27  ? 223 TYR A CZ  1 
ATOM   1387  O OH  . TYR A 1 203 ? 128.018 146.562 79.832  1.00 35.01  ? 223 TYR A OH  1 
ATOM   1388  N N   . GLY A 1 204 ? 127.719 139.997 79.366  1.00 33.78  ? 224 GLY A N   1 
ATOM   1389  C CA  . GLY A 1 204 ? 127.190 139.860 80.711  1.00 34.51  ? 224 GLY A CA  1 
ATOM   1390  C C   . GLY A 1 204 ? 127.991 138.864 81.542  1.00 35.37  ? 224 GLY A C   1 
ATOM   1391  O O   . GLY A 1 204 ? 128.346 139.154 82.681  1.00 35.99  ? 224 GLY A O   1 
ATOM   1392  N N   . GLU A 1 205 ? 128.276 137.696 80.956  1.00 36.71  ? 225 GLU A N   1 
ATOM   1393  C CA  . GLU A 1 205 ? 128.898 136.606 81.690  1.00 38.49  ? 225 GLU A CA  1 
ATOM   1394  C C   . GLU A 1 205 ? 130.308 136.999 82.119  1.00 37.85  ? 225 GLU A C   1 
ATOM   1395  O O   . GLU A 1 205 ? 130.645 136.859 83.287  1.00 38.47  ? 225 GLU A O   1 
ATOM   1396  C CB  . GLU A 1 205 ? 128.885 135.326 80.858  1.00 41.34  ? 225 GLU A CB  1 
ATOM   1397  C CG  . GLU A 1 205 ? 127.495 134.732 80.731  1.00 44.13  ? 225 GLU A CG  1 
ATOM   1398  C CD  . GLU A 1 205 ? 127.475 133.216 80.657  1.00 46.81  ? 225 GLU A CD  1 
ATOM   1399  O OE1 . GLU A 1 205 ? 126.903 132.673 79.688  1.00 47.68  ? 225 GLU A OE1 1 
ATOM   1400  O OE2 . GLU A 1 205 ? 128.043 132.587 81.572  1.00 48.45  ? 225 GLU A OE2 1 
ATOM   1401  N N   . SER A 1 206 ? 131.116 137.495 81.178  1.00 37.65  ? 226 SER A N   1 
ATOM   1402  C CA  . SER A 1 206 ? 132.487 137.888 81.461  1.00 37.90  ? 226 SER A CA  1 
ATOM   1403  C C   . SER A 1 206 ? 132.520 139.049 82.448  1.00 37.96  ? 226 SER A C   1 
ATOM   1404  O O   . SER A 1 206 ? 133.320 139.048 83.381  1.00 38.93  ? 226 SER A O   1 
ATOM   1405  C CB  . SER A 1 206 ? 133.218 138.251 80.199  1.00 38.54  ? 226 SER A CB  1 
ATOM   1406  O OG  . SER A 1 206 ? 133.071 137.227 79.234  1.00 38.85  ? 226 SER A OG  1 
ATOM   1407  N N   . GLY A 1 207 ? 131.655 140.044 82.217  1.00 37.47  ? 227 GLY A N   1 
ATOM   1408  C CA  . GLY A 1 207 ? 131.551 141.198 83.094  1.00 37.18  ? 227 GLY A CA  1 
ATOM   1409  C C   . GLY A 1 207 ? 131.269 140.781 84.535  1.00 37.43  ? 227 GLY A C   1 
ATOM   1410  O O   . GLY A 1 207 ? 131.915 141.250 85.468  1.00 37.84  ? 227 GLY A O   1 
ATOM   1411  N N   . MET A 1 208 ? 130.299 139.881 84.703  1.00 38.52  ? 228 MET A N   1 
ATOM   1412  C CA  . MET A 1 208 ? 129.857 139.501 86.031  1.00 39.97  ? 228 MET A CA  1 
ATOM   1413  C C   . MET A 1 208 ? 130.875 138.566 86.682  1.00 40.90  ? 228 MET A C   1 
ATOM   1414  O O   . MET A 1 208 ? 131.006 138.572 87.898  1.00 42.59  ? 228 MET A O   1 
ATOM   1415  C CB  . MET A 1 208 ? 128.478 138.841 85.976  1.00 41.08  ? 228 MET A CB  1 
ATOM   1416  C CG  . MET A 1 208 ? 127.825 138.639 87.336  1.00 42.53  ? 228 MET A CG  1 
ATOM   1417  S SD  . MET A 1 208 ? 128.032 139.997 88.535  1.00 45.28  ? 228 MET A SD  1 
ATOM   1418  C CE  . MET A 1 208 ? 127.530 141.455 87.620  1.00 44.74  ? 228 MET A CE  1 
ATOM   1419  N N   . GLU A 1 209 ? 131.620 137.788 85.891  1.00 41.57  ? 229 GLU A N   1 
ATOM   1420  C CA  . GLU A 1 209 ? 132.682 136.959 86.447  1.00 42.57  ? 229 GLU A CA  1 
ATOM   1421  C C   . GLU A 1 209 ? 133.777 137.864 87.014  1.00 41.15  ? 229 GLU A C   1 
ATOM   1422  O O   . GLU A 1 209 ? 134.273 137.628 88.115  1.00 41.85  ? 229 GLU A O   1 
ATOM   1423  C CB  . GLU A 1 209 ? 133.240 136.006 85.387  1.00 45.50  ? 229 GLU A CB  1 
ATOM   1424  C CG  . GLU A 1 209 ? 133.324 134.557 85.839  1.00 48.34  ? 229 GLU A CG  1 
ATOM   1425  C CD  . GLU A 1 209 ? 133.335 133.553 84.697  1.00 50.76  ? 229 GLU A CD  1 
ATOM   1426  O OE1 . GLU A 1 209 ? 134.260 133.618 83.860  1.00 51.95  ? 229 GLU A OE1 1 
ATOM   1427  O OE2 . GLU A 1 209 ? 132.411 132.710 84.638  1.00 51.79  ? 229 GLU A OE2 1 
ATOM   1428  N N   . ALA A 1 210 ? 134.142 138.909 86.264  1.00 39.72  ? 230 ALA A N   1 
ATOM   1429  C CA  . ALA A 1 210 ? 135.158 139.847 86.714  1.00 38.79  ? 230 ALA A CA  1 
ATOM   1430  C C   . ALA A 1 210 ? 134.681 140.563 87.974  1.00 38.12  ? 230 ALA A C   1 
ATOM   1431  O O   . ALA A 1 210 ? 135.438 140.700 88.928  1.00 38.65  ? 230 ALA A O   1 
ATOM   1432  C CB  . ALA A 1 210 ? 135.486 140.824 85.616  1.00 39.20  ? 230 ALA A CB  1 
ATOM   1433  N N   . PHE A 1 211 ? 133.421 141.013 87.965  1.00 38.28  ? 231 PHE A N   1 
ATOM   1434  C CA  . PHE A 1 211 ? 132.848 141.720 89.098  1.00 38.99  ? 231 PHE A CA  1 
ATOM   1435  C C   . PHE A 1 211 ? 132.837 140.822 90.333  1.00 40.72  ? 231 PHE A C   1 
ATOM   1436  O O   . PHE A 1 211 ? 133.174 141.261 91.427  1.00 41.57  ? 231 PHE A O   1 
ATOM   1437  C CB  . PHE A 1 211 ? 131.428 142.201 88.791  1.00 38.29  ? 231 PHE A CB  1 
ATOM   1438  C CG  . PHE A 1 211 ? 130.763 142.898 89.950  1.00 38.31  ? 231 PHE A CG  1 
ATOM   1439  C CD1 . PHE A 1 211 ? 131.119 144.193 90.295  1.00 38.59  ? 231 PHE A CD1 1 
ATOM   1440  C CD2 . PHE A 1 211 ? 129.804 142.254 90.715  1.00 38.19  ? 231 PHE A CD2 1 
ATOM   1441  C CE1 . PHE A 1 211 ? 130.508 144.839 91.358  1.00 38.18  ? 231 PHE A CE1 1 
ATOM   1442  C CE2 . PHE A 1 211 ? 129.206 142.897 91.789  1.00 37.98  ? 231 PHE A CE2 1 
ATOM   1443  C CZ  . PHE A 1 211 ? 129.564 144.186 92.113  1.00 37.79  ? 231 PHE A CZ  1 
ATOM   1444  N N   . LYS A 1 212 ? 132.439 139.563 90.146  1.00 42.88  ? 232 LYS A N   1 
ATOM   1445  C CA  . LYS A 1 212 ? 132.367 138.602 91.233  1.00 45.13  ? 232 LYS A CA  1 
ATOM   1446  C C   . LYS A 1 212 ? 133.755 138.394 91.834  1.00 47.54  ? 232 LYS A C   1 
ATOM   1447  O O   . LYS A 1 212 ? 133.906 138.409 93.049  1.00 49.29  ? 232 LYS A O   1 
ATOM   1448  C CB  . LYS A 1 212 ? 131.779 137.284 90.727  1.00 46.27  ? 232 LYS A CB  1 
ATOM   1449  C CG  . LYS A 1 212 ? 131.107 136.428 91.788  1.00 48.24  ? 232 LYS A CG  1 
ATOM   1450  C CD  . LYS A 1 212 ? 130.292 135.280 91.219  1.00 49.51  ? 232 LYS A CD  1 
ATOM   1451  C CE  . LYS A 1 212 ? 129.314 135.675 90.128  1.00 49.44  ? 232 LYS A CE  1 
ATOM   1452  N NZ  . LYS A 1 212 ? 128.423 136.787 90.535  1.00 48.57  ? 232 LYS A NZ  1 
ATOM   1453  N N   . ASP A 1 213 ? 134.766 138.212 90.980  1.00 49.68  ? 233 ASP A N   1 
ATOM   1454  C CA  . ASP A 1 213 ? 136.128 138.001 91.448  1.00 51.72  ? 233 ASP A CA  1 
ATOM   1455  C C   . ASP A 1 213 ? 136.586 139.184 92.300  1.00 51.60  ? 233 ASP A C   1 
ATOM   1456  O O   . ASP A 1 213 ? 136.947 139.012 93.459  1.00 52.66  ? 233 ASP A O   1 
ATOM   1457  C CB  . ASP A 1 213 ? 137.077 137.749 90.275  1.00 53.82  ? 233 ASP A CB  1 
ATOM   1458  C CG  . ASP A 1 213 ? 136.874 136.400 89.607  1.00 55.93  ? 233 ASP A CG  1 
ATOM   1459  O OD1 . ASP A 1 213 ? 136.069 135.593 90.122  1.00 56.41  ? 233 ASP A OD1 1 
ATOM   1460  O OD2 . ASP A 1 213 ? 137.529 136.163 88.578  1.00 56.95  ? 233 ASP A OD2 1 
ATOM   1461  N N   . MET A 1 214 ? 136.548 140.387 91.724  1.00 51.72  ? 234 MET A N   1 
ATOM   1462  C CA  . MET A 1 214 ? 137.107 141.572 92.354  1.00 52.42  ? 234 MET A CA  1 
ATOM   1463  C C   . MET A 1 214 ? 136.281 141.996 93.571  1.00 53.71  ? 234 MET A C   1 
ATOM   1464  O O   . MET A 1 214 ? 136.796 142.694 94.437  1.00 54.76  ? 234 MET A O   1 
ATOM   1465  C CB  . MET A 1 214 ? 137.136 142.719 91.337  1.00 51.78  ? 234 MET A CB  1 
ATOM   1466  C CG  . MET A 1 214 ? 138.066 142.463 90.174  1.00 51.84  ? 234 MET A CG  1 
ATOM   1467  S SD  . MET A 1 214 ? 137.513 143.293 88.661  1.00 52.24  ? 234 MET A SD  1 
ATOM   1468  C CE  . MET A 1 214 ? 138.856 142.876 87.550  1.00 52.57  ? 234 MET A CE  1 
ATOM   1469  N N   . SER A 1 215 ? 134.987 141.656 93.597  1.00 54.36  ? 235 SER A N   1 
ATOM   1470  C CA  . SER A 1 215 ? 134.121 142.026 94.702  1.00 55.23  ? 235 SER A CA  1 
ATOM   1471  C C   . SER A 1 215 ? 134.334 141.081 95.881  1.00 58.03  ? 235 SER A C   1 
ATOM   1472  O O   . SER A 1 215 ? 134.478 141.527 97.014  1.00 59.96  ? 235 SER A O   1 
ATOM   1473  C CB  . SER A 1 215 ? 132.680 142.069 94.266  1.00 55.08  ? 235 SER A CB  1 
ATOM   1474  O OG  . SER A 1 215 ? 132.215 140.772 93.931  1.00 55.11  ? 235 SER A OG  1 
ATOM   1475  N N   . ALA A 1 216 ? 134.346 139.771 95.612  1.00 60.64  ? 236 ALA A N   1 
ATOM   1476  C CA  . ALA A 1 216 ? 134.592 138.778 96.647  1.00 63.86  ? 236 ALA A CA  1 
ATOM   1477  C C   . ALA A 1 216 ? 135.990 138.964 97.236  1.00 65.81  ? 236 ALA A C   1 
ATOM   1478  O O   . ALA A 1 216 ? 136.212 138.660 98.406  1.00 66.06  ? 236 ALA A O   1 
ATOM   1479  C CB  . ALA A 1 216 ? 134.409 137.384 96.098  1.00 64.95  ? 236 ALA A CB  1 
ATOM   1480  N N   . LYS A 1 217 ? 136.922 139.464 96.417  1.00 68.34  ? 237 LYS A N   1 
ATOM   1481  C CA  . LYS A 1 217 ? 138.277 139.726 96.872  1.00 71.95  ? 237 LYS A CA  1 
ATOM   1482  C C   . LYS A 1 217 ? 138.281 140.868 97.888  1.00 70.95  ? 237 LYS A C   1 
ATOM   1483  O O   . LYS A 1 217 ? 138.985 140.790 98.889  1.00 71.86  ? 237 LYS A O   1 
ATOM   1484  C CB  . LYS A 1 217 ? 139.183 140.048 95.680  1.00 75.84  ? 237 LYS A CB  1 
ATOM   1485  C CG  . LYS A 1 217 ? 140.667 140.158 96.003  1.00 79.37  ? 237 LYS A CG  1 
ATOM   1486  C CD  . LYS A 1 217 ? 141.544 140.436 94.796  1.00 82.55  ? 237 LYS A CD  1 
ATOM   1487  C CE  . LYS A 1 217 ? 141.412 139.415 93.683  1.00 83.99  ? 237 LYS A CE  1 
ATOM   1488  N NZ  . LYS A 1 217 ? 141.536 138.024 94.184  1.00 84.52  ? 237 LYS A NZ  1 
ATOM   1489  N N   . GLU A 1 218 ? 137.491 141.921 97.632  1.00 69.58  ? 238 GLU A N   1 
ATOM   1490  C CA  . GLU A 1 218 ? 137.565 143.152 98.405  1.00 69.11  ? 238 GLU A CA  1 
ATOM   1491  C C   . GLU A 1 218 ? 136.325 143.352 99.279  1.00 65.81  ? 238 GLU A C   1 
ATOM   1492  O O   . GLU A 1 218 ? 135.901 144.485 99.490  1.00 64.88  ? 238 GLU A O   1 
ATOM   1493  C CB  . GLU A 1 218 ? 137.746 144.347 97.467  1.00 71.68  ? 238 GLU A CB  1 
ATOM   1494  C CG  . GLU A 1 218 ? 139.181 144.551 97.028  1.00 74.65  ? 238 GLU A CG  1 
ATOM   1495  C CD  . GLU A 1 218 ? 139.351 145.512 95.865  1.00 77.05  ? 238 GLU A CD  1 
ATOM   1496  O OE1 . GLU A 1 218 ? 140.442 145.513 95.257  1.00 78.04  ? 238 GLU A OE1 1 
ATOM   1497  O OE2 . GLU A 1 218 ? 138.400 146.269 95.577  1.00 77.18  ? 238 GLU A OE2 1 
ATOM   1498  N N   . GLY A 1 219 ? 135.738 142.256 99.777  1.00 63.22  ? 239 GLY A N   1 
ATOM   1499  C CA  . GLY A 1 219 ? 134.824 142.318 100.907 1.00 62.02  ? 239 GLY A CA  1 
ATOM   1500  C C   . GLY A 1 219 ? 133.351 142.353 100.506 1.00 60.47  ? 239 GLY A C   1 
ATOM   1501  O O   . GLY A 1 219 ? 132.483 142.153 101.356 1.00 60.83  ? 239 GLY A O   1 
ATOM   1502  N N   . ILE A 1 220 ? 133.068 142.614 99.223  1.00 57.90  ? 240 ILE A N   1 
ATOM   1503  C CA  . ILE A 1 220 ? 131.690 142.685 98.762  1.00 55.16  ? 240 ILE A CA  1 
ATOM   1504  C C   . ILE A 1 220 ? 131.164 141.255 98.676  1.00 54.19  ? 240 ILE A C   1 
ATOM   1505  O O   . ILE A 1 220 ? 131.866 140.367 98.191  1.00 53.51  ? 240 ILE A O   1 
ATOM   1506  C CB  . ILE A 1 220 ? 131.574 143.419 97.408  1.00 53.74  ? 240 ILE A CB  1 
ATOM   1507  C CG1 . ILE A 1 220 ? 132.477 144.652 97.310  1.00 53.78  ? 240 ILE A CG1 1 
ATOM   1508  C CG2 . ILE A 1 220 ? 130.134 143.768 97.085  1.00 53.04  ? 240 ILE A CG2 1 
ATOM   1509  C CD1 . ILE A 1 220 ? 132.218 145.697 98.364  1.00 54.64  ? 240 ILE A CD1 1 
ATOM   1510  N N   . CYS A 1 221 ? 129.917 141.048 99.122  1.00 55.88  ? 241 CYS A N   1 
ATOM   1511  C CA  . CYS A 1 221 ? 129.284 139.740 99.063  1.00 58.75  ? 241 CYS A CA  1 
ATOM   1512  C C   . CYS A 1 221 ? 128.027 139.819 98.203  1.00 57.06  ? 241 CYS A C   1 
ATOM   1513  O O   . CYS A 1 221 ? 127.237 140.740 98.344  1.00 57.98  ? 241 CYS A O   1 
ATOM   1514  C CB  . CYS A 1 221 ? 128.923 139.234 100.453 1.00 63.62  ? 241 CYS A CB  1 
ATOM   1515  S SG  . CYS A 1 221 ? 130.360 138.867 101.492 1.00 73.70  ? 241 CYS A SG  1 
ATOM   1516  N N   . ILE A 1 222 ? 127.840 138.834 97.323  1.00 55.42  ? 242 ILE A N   1 
ATOM   1517  C CA  . ILE A 1 222 ? 126.710 138.829 96.410  1.00 54.22  ? 242 ILE A CA  1 
ATOM   1518  C C   . ILE A 1 222 ? 125.611 137.942 96.987  1.00 54.49  ? 242 ILE A C   1 
ATOM   1519  O O   . ILE A 1 222 ? 125.847 136.766 97.260  1.00 54.61  ? 242 ILE A O   1 
ATOM   1520  C CB  . ILE A 1 222 ? 127.160 138.369 95.011  1.00 53.43  ? 242 ILE A CB  1 
ATOM   1521  C CG1 . ILE A 1 222 ? 128.098 139.397 94.371  1.00 53.04  ? 242 ILE A CG1 1 
ATOM   1522  C CG2 . ILE A 1 222 ? 125.954 138.072 94.128  1.00 53.37  ? 242 ILE A CG2 1 
ATOM   1523  C CD1 . ILE A 1 222 ? 128.571 139.023 92.985  1.00 53.71  ? 242 ILE A CD1 1 
ATOM   1524  N N   . ALA A 1 223 ? 124.417 138.523 97.158  1.00 55.10  ? 243 ALA A N   1 
ATOM   1525  C CA  . ALA A 1 223 ? 123.272 137.801 97.683  1.00 56.72  ? 243 ALA A CA  1 
ATOM   1526  C C   . ALA A 1 223 ? 122.948 136.614 96.782  1.00 58.35  ? 243 ALA A C   1 
ATOM   1527  O O   . ALA A 1 223 ? 122.866 135.480 97.252  1.00 59.16  ? 243 ALA A O   1 
ATOM   1528  C CB  . ALA A 1 223 ? 122.092 138.731 97.816  1.00 57.25  ? 243 ALA A CB  1 
ATOM   1529  N N   . HIS A 1 224 ? 122.765 136.894 95.487  1.00 60.00  ? 244 HIS A N   1 
ATOM   1530  C CA  . HIS A 1 224 ? 122.539 135.849 94.505  1.00 61.90  ? 244 HIS A CA  1 
ATOM   1531  C C   . HIS A 1 224 ? 122.777 136.422 93.111  1.00 58.33  ? 244 HIS A C   1 
ATOM   1532  O O   . HIS A 1 224 ? 122.318 137.518 92.810  1.00 57.09  ? 244 HIS A O   1 
ATOM   1533  C CB  . HIS A 1 224 ? 121.120 135.289 94.637  1.00 65.76  ? 244 HIS A CB  1 
ATOM   1534  C CG  . HIS A 1 224 ? 120.980 133.859 94.237  1.00 70.67  ? 244 HIS A CG  1 
ATOM   1535  N ND1 . HIS A 1 224 ? 119.741 133.284 94.060  1.00 73.74  ? 244 HIS A ND1 1 
ATOM   1536  C CD2 . HIS A 1 224 ? 121.876 132.893 93.978  1.00 73.50  ? 244 HIS A CD2 1 
ATOM   1537  C CE1 . HIS A 1 224 ? 119.892 132.017 93.704  1.00 76.24  ? 244 HIS A CE1 1 
ATOM   1538  N NE2 . HIS A 1 224 ? 121.182 131.757 93.651  1.00 75.90  ? 244 HIS A NE2 1 
ATOM   1539  N N   . SER A 1 225 ? 123.520 135.680 92.282  1.00 55.61  ? 245 SER A N   1 
ATOM   1540  C CA  . SER A 1 225 ? 123.800 136.088 90.916  1.00 53.06  ? 245 SER A CA  1 
ATOM   1541  C C   . SER A 1 225 ? 122.769 135.463 89.983  1.00 51.23  ? 245 SER A C   1 
ATOM   1542  O O   . SER A 1 225 ? 122.627 134.244 89.945  1.00 51.57  ? 245 SER A O   1 
ATOM   1543  C CB  . SER A 1 225 ? 125.197 135.707 90.514  1.00 53.19  ? 245 SER A CB  1 
ATOM   1544  O OG  . SER A 1 225 ? 125.536 136.277 89.257  1.00 52.97  ? 245 SER A OG  1 
ATOM   1545  N N   . TYR A 1 226 ? 122.042 136.312 89.246  1.00 49.26  ? 246 TYR A N   1 
ATOM   1546  C CA  . TYR A 1 226 ? 121.001 135.851 88.339  1.00 47.85  ? 246 TYR A CA  1 
ATOM   1547  C C   . TYR A 1 226 ? 121.413 136.128 86.897  1.00 45.78  ? 246 TYR A C   1 
ATOM   1548  O O   . TYR A 1 226 ? 122.237 137.002 86.627  1.00 45.03  ? 246 TYR A O   1 
ATOM   1549  C CB  . TYR A 1 226 ? 119.658 136.524 88.636  1.00 48.99  ? 246 TYR A CB  1 
ATOM   1550  C CG  . TYR A 1 226 ? 119.251 136.507 90.086  1.00 51.14  ? 246 TYR A CG  1 
ATOM   1551  C CD1 . TYR A 1 226 ? 118.724 135.375 90.687  1.00 52.83  ? 246 TYR A CD1 1 
ATOM   1552  C CD2 . TYR A 1 226 ? 119.440 137.631 90.870  1.00 52.60  ? 246 TYR A CD2 1 
ATOM   1553  C CE1 . TYR A 1 226 ? 118.367 135.371 92.027  1.00 54.08  ? 246 TYR A CE1 1 
ATOM   1554  C CE2 . TYR A 1 226 ? 119.118 137.634 92.216  1.00 54.09  ? 246 TYR A CE2 1 
ATOM   1555  C CZ  . TYR A 1 226 ? 118.564 136.508 92.793  1.00 55.31  ? 246 TYR A CZ  1 
ATOM   1556  O OH  . TYR A 1 226 ? 118.240 136.534 94.128  1.00 57.42  ? 246 TYR A OH  1 
ATOM   1557  N N   . LYS A 1 227 ? 120.798 135.376 85.981  1.00 44.37  ? 247 LYS A N   1 
ATOM   1558  C CA  . LYS A 1 227 ? 121.018 135.532 84.557  1.00 43.27  ? 247 LYS A CA  1 
ATOM   1559  C C   . LYS A 1 227 ? 119.660 135.581 83.868  1.00 42.11  ? 247 LYS A C   1 
ATOM   1560  O O   . LYS A 1 227 ? 118.703 134.962 84.334  1.00 43.16  ? 247 LYS A O   1 
ATOM   1561  C CB  . LYS A 1 227 ? 121.805 134.345 83.994  1.00 44.27  ? 247 LYS A CB  1 
ATOM   1562  C CG  . LYS A 1 227 ? 122.752 133.639 84.957  1.00 46.31  ? 247 LYS A CG  1 
ATOM   1563  C CD  . LYS A 1 227 ? 122.866 132.149 84.699  1.00 47.83  ? 247 LYS A CD  1 
ATOM   1564  C CE  . LYS A 1 227 ? 123.227 131.818 83.267  1.00 48.83  ? 247 LYS A CE  1 
ATOM   1565  N NZ  . LYS A 1 227 ? 123.104 130.367 82.994  1.00 49.52  ? 247 LYS A NZ  1 
ATOM   1566  N N   . ILE A 1 228 ? 119.594 136.299 82.746  1.00 41.21  ? 248 ILE A N   1 
ATOM   1567  C CA  . ILE A 1 228 ? 118.375 136.356 81.964  1.00 41.10  ? 248 ILE A CA  1 
ATOM   1568  C C   . ILE A 1 228 ? 118.722 136.784 80.546  1.00 41.55  ? 248 ILE A C   1 
ATOM   1569  O O   . ILE A 1 228 ? 119.616 137.598 80.346  1.00 41.50  ? 248 ILE A O   1 
ATOM   1570  C CB  . ILE A 1 228 ? 117.349 137.302 82.613  1.00 40.79  ? 248 ILE A CB  1 
ATOM   1571  C CG1 . ILE A 1 228 ? 116.039 137.319 81.827  1.00 41.15  ? 248 ILE A CG1 1 
ATOM   1572  C CG2 . ILE A 1 228 ? 117.923 138.699 82.788  1.00 40.63  ? 248 ILE A CG2 1 
ATOM   1573  C CD1 . ILE A 1 228 ? 114.861 137.806 82.628  1.00 41.60  ? 248 ILE A CD1 1 
ATOM   1574  N N   . TYR A 1 229 ? 118.002 136.220 79.575  1.00 42.95  ? 249 TYR A N   1 
ATOM   1575  C CA  . TYR A 1 229 ? 118.164 136.589 78.179  1.00 44.61  ? 249 TYR A CA  1 
ATOM   1576  C C   . TYR A 1 229 ? 117.473 137.928 77.940  1.00 45.19  ? 249 TYR A C   1 
ATOM   1577  O O   . TYR A 1 229 ? 116.482 138.244 78.592  1.00 45.82  ? 249 TYR A O   1 
ATOM   1578  C CB  . TYR A 1 229 ? 117.594 135.503 77.265  1.00 46.40  ? 249 TYR A CB  1 
ATOM   1579  C CG  . TYR A 1 229 ? 118.512 134.329 77.043  1.00 48.16  ? 249 TYR A CG  1 
ATOM   1580  C CD1 . TYR A 1 229 ? 119.508 134.377 76.083  1.00 49.79  ? 249 TYR A CD1 1 
ATOM   1581  C CD2 . TYR A 1 229 ? 118.408 133.180 77.812  1.00 49.30  ? 249 TYR A CD2 1 
ATOM   1582  C CE1 . TYR A 1 229 ? 120.364 133.307 75.874  1.00 50.86  ? 249 TYR A CE1 1 
ATOM   1583  C CE2 . TYR A 1 229 ? 119.266 132.108 77.628  1.00 50.82  ? 249 TYR A CE2 1 
ATOM   1584  C CZ  . TYR A 1 229 ? 120.242 132.167 76.648  1.00 51.38  ? 249 TYR A CZ  1 
ATOM   1585  O OH  . TYR A 1 229 ? 121.089 131.103 76.458  1.00 51.53  ? 249 TYR A OH  1 
ATOM   1586  N N   . SER A 1 230 ? 118.011 138.706 76.997  1.00 45.97  ? 250 SER A N   1 
ATOM   1587  C CA  . SER A 1 230 ? 117.474 140.018 76.681  1.00 47.06  ? 250 SER A CA  1 
ATOM   1588  C C   . SER A 1 230 ? 116.057 139.899 76.125  1.00 48.61  ? 250 SER A C   1 
ATOM   1589  O O   . SER A 1 230 ? 115.207 140.733 76.421  1.00 48.98  ? 250 SER A O   1 
ATOM   1590  C CB  . SER A 1 230 ? 118.378 140.748 75.720  1.00 48.05  ? 250 SER A CB  1 
ATOM   1591  O OG  . SER A 1 230 ? 118.673 139.942 74.592  1.00 48.81  ? 250 SER A OG  1 
ATOM   1592  N N   . ASN A 1 231 ? 115.808 138.846 75.336  1.00 50.98  ? 251 ASN A N   1 
ATOM   1593  C CA  . ASN A 1 231 ? 114.541 138.672 74.644  1.00 52.62  ? 251 ASN A CA  1 
ATOM   1594  C C   . ASN A 1 231 ? 113.629 137.714 75.412  1.00 55.20  ? 251 ASN A C   1 
ATOM   1595  O O   . ASN A 1 231 ? 112.725 137.123 74.824  1.00 56.55  ? 251 ASN A O   1 
ATOM   1596  C CB  . ASN A 1 231 ? 114.770 138.179 73.213  1.00 52.08  ? 251 ASN A CB  1 
ATOM   1597  C CG  . ASN A 1 231 ? 115.560 136.888 73.155  1.00 52.01  ? 251 ASN A CG  1 
ATOM   1598  O OD1 . ASN A 1 231 ? 115.897 136.313 74.187  1.00 51.51  ? 251 ASN A OD1 1 
ATOM   1599  N ND2 . ASN A 1 231 ? 115.873 136.433 71.954  1.00 52.67  ? 251 ASN A ND2 1 
ATOM   1600  N N   . ALA A 1 232 ? 113.857 137.562 76.723  1.00 57.04  ? 252 ALA A N   1 
ATOM   1601  C CA  . ALA A 1 232 ? 112.999 136.724 77.545  1.00 58.53  ? 252 ALA A CA  1 
ATOM   1602  C C   . ALA A 1 232 ? 111.622 137.372 77.671  1.00 61.63  ? 252 ALA A C   1 
ATOM   1603  O O   . ALA A 1 232 ? 111.492 138.594 77.607  1.00 61.73  ? 252 ALA A O   1 
ATOM   1604  C CB  . ALA A 1 232 ? 113.624 136.495 78.898  1.00 57.64  ? 252 ALA A CB  1 
ATOM   1605  N N   . GLY A 1 233 ? 110.598 136.534 77.857  1.00 64.98  ? 253 GLY A N   1 
ATOM   1606  C CA  . GLY A 1 233 ? 109.227 137.003 77.970  1.00 67.13  ? 253 GLY A CA  1 
ATOM   1607  C C   . GLY A 1 233 ? 108.976 137.751 79.276  1.00 68.51  ? 253 GLY A C   1 
ATOM   1608  O O   . GLY A 1 233 ? 109.853 137.837 80.138  1.00 68.54  ? 253 GLY A O   1 
ATOM   1609  N N   . GLU A 1 234 ? 107.748 138.260 79.414  1.00 70.73  ? 254 GLU A N   1 
ATOM   1610  C CA  . GLU A 1 234 ? 107.352 139.060 80.563  1.00 73.09  ? 254 GLU A CA  1 
ATOM   1611  C C   . GLU A 1 234 ? 107.429 138.207 81.829  1.00 72.59  ? 254 GLU A C   1 
ATOM   1612  O O   . GLU A 1 234 ? 107.812 138.691 82.891  1.00 71.63  ? 254 GLU A O   1 
ATOM   1613  C CB  . GLU A 1 234 ? 105.922 139.596 80.414  1.00 75.91  ? 254 GLU A CB  1 
ATOM   1614  C CG  . GLU A 1 234 ? 105.585 140.207 79.059  1.00 78.47  ? 254 GLU A CG  1 
ATOM   1615  C CD  . GLU A 1 234 ? 105.766 141.709 78.896  1.00 80.68  ? 254 GLU A CD  1 
ATOM   1616  O OE1 . GLU A 1 234 ? 106.483 142.333 79.703  1.00 80.92  ? 254 GLU A OE1 1 
ATOM   1617  O OE2 . GLU A 1 234 ? 105.161 142.259 77.959  1.00 82.23  ? 254 GLU A OE2 1 
ATOM   1618  N N   . GLN A 1 235 ? 107.067 136.925 81.699  1.00 73.39  ? 255 GLN A N   1 
ATOM   1619  C CA  . GLN A 1 235 ? 106.966 136.043 82.847  1.00 74.51  ? 255 GLN A CA  1 
ATOM   1620  C C   . GLN A 1 235 ? 108.354 135.796 83.430  1.00 69.85  ? 255 GLN A C   1 
ATOM   1621  O O   . GLN A 1 235 ? 108.500 135.733 84.649  1.00 68.01  ? 255 GLN A O   1 
ATOM   1622  C CB  . GLN A 1 235 ? 106.262 134.741 82.456  1.00 79.39  ? 255 GLN A CB  1 
ATOM   1623  C CG  . GLN A 1 235 ? 105.439 134.130 83.584  1.00 84.32  ? 255 GLN A CG  1 
ATOM   1624  C CD  . GLN A 1 235 ? 104.637 135.166 84.340  1.00 88.06  ? 255 GLN A CD  1 
ATOM   1625  O OE1 . GLN A 1 235 ? 104.017 136.050 83.750  1.00 89.12  ? 255 GLN A OE1 1 
ATOM   1626  N NE2 . GLN A 1 235 ? 104.670 135.088 85.661  1.00 88.65  ? 255 GLN A NE2 1 
ATOM   1627  N N   . SER A 1 236 ? 109.365 135.668 82.561  1.00 65.49  ? 256 SER A N   1 
ATOM   1628  C CA  . SER A 1 236 ? 110.724 135.402 83.006  1.00 62.38  ? 256 SER A CA  1 
ATOM   1629  C C   . SER A 1 236 ? 111.254 136.581 83.822  1.00 59.94  ? 256 SER A C   1 
ATOM   1630  O O   . SER A 1 236 ? 111.860 136.381 84.874  1.00 60.12  ? 256 SER A O   1 
ATOM   1631  C CB  . SER A 1 236 ? 111.625 135.083 81.842  1.00 62.52  ? 256 SER A CB  1 
ATOM   1632  O OG  . SER A 1 236 ? 112.870 134.567 82.294  1.00 63.20  ? 256 SER A OG  1 
ATOM   1633  N N   . PHE A 1 237 ? 111.007 137.806 83.338  1.00 57.29  ? 257 PHE A N   1 
ATOM   1634  C CA  . PHE A 1 237 ? 111.415 139.009 84.048  1.00 55.10  ? 257 PHE A CA  1 
ATOM   1635  C C   . PHE A 1 237 ? 110.664 139.138 85.370  1.00 56.56  ? 257 PHE A C   1 
ATOM   1636  O O   . PHE A 1 237 ? 111.238 139.585 86.360  1.00 55.98  ? 257 PHE A O   1 
ATOM   1637  C CB  . PHE A 1 237 ? 111.213 140.247 83.171  1.00 53.77  ? 257 PHE A CB  1 
ATOM   1638  C CG  . PHE A 1 237 ? 112.351 140.499 82.219  1.00 53.03  ? 257 PHE A CG  1 
ATOM   1639  C CD1 . PHE A 1 237 ? 113.548 141.029 82.677  1.00 52.42  ? 257 PHE A CD1 1 
ATOM   1640  C CD2 . PHE A 1 237 ? 112.243 140.169 80.878  1.00 52.67  ? 257 PHE A CD2 1 
ATOM   1641  C CE1 . PHE A 1 237 ? 114.607 141.246 81.810  1.00 51.36  ? 257 PHE A CE1 1 
ATOM   1642  C CE2 . PHE A 1 237 ? 113.301 140.391 80.011  1.00 52.35  ? 257 PHE A CE2 1 
ATOM   1643  C CZ  . PHE A 1 237 ? 114.481 140.928 80.478  1.00 51.74  ? 257 PHE A CZ  1 
ATOM   1644  N N   . ASP A 1 238 ? 109.383 138.751 85.376  1.00 59.47  ? 258 ASP A N   1 
ATOM   1645  C CA  . ASP A 1 238 ? 108.573 138.791 86.584  1.00 61.22  ? 258 ASP A CA  1 
ATOM   1646  C C   . ASP A 1 238 ? 109.167 137.855 87.634  1.00 59.84  ? 258 ASP A C   1 
ATOM   1647  O O   . ASP A 1 238 ? 109.288 138.229 88.796  1.00 59.58  ? 258 ASP A O   1 
ATOM   1648  C CB  . ASP A 1 238 ? 107.110 138.444 86.294  1.00 64.00  ? 258 ASP A CB  1 
ATOM   1649  C CG  . ASP A 1 238 ? 106.346 139.562 85.606  1.00 66.35  ? 258 ASP A CG  1 
ATOM   1650  O OD1 . ASP A 1 238 ? 106.414 140.696 86.108  1.00 67.36  ? 258 ASP A OD1 1 
ATOM   1651  O OD2 . ASP A 1 238 ? 105.688 139.292 84.572  1.00 67.22  ? 258 ASP A OD2 1 
ATOM   1652  N N   . LYS A 1 239 ? 109.545 136.644 87.214  1.00 59.53  ? 259 LYS A N   1 
ATOM   1653  C CA  . LYS A 1 239 ? 110.110 135.658 88.120  1.00 60.72  ? 259 LYS A CA  1 
ATOM   1654  C C   . LYS A 1 239 ? 111.461 136.141 88.643  1.00 58.94  ? 259 LYS A C   1 
ATOM   1655  O O   . LYS A 1 239 ? 111.766 135.968 89.822  1.00 59.15  ? 259 LYS A O   1 
ATOM   1656  C CB  . LYS A 1 239 ? 110.228 134.299 87.424  1.00 64.11  ? 259 LYS A CB  1 
ATOM   1657  C CG  . LYS A 1 239 ? 108.898 133.663 87.036  1.00 67.21  ? 259 LYS A CG  1 
ATOM   1658  C CD  . LYS A 1 239 ? 108.989 132.184 86.742  1.00 69.94  ? 259 LYS A CD  1 
ATOM   1659  C CE  . LYS A 1 239 ? 109.523 131.875 85.360  1.00 71.76  ? 259 LYS A CE  1 
ATOM   1660  N NZ  . LYS A 1 239 ? 108.447 131.896 84.344  1.00 71.97  ? 259 LYS A NZ  1 
ATOM   1661  N N   . LEU A 1 240 ? 112.266 136.748 87.764  1.00 57.99  ? 260 LEU A N   1 
ATOM   1662  C CA  . LEU A 1 240 ? 113.564 137.274 88.158  1.00 57.15  ? 260 LEU A CA  1 
ATOM   1663  C C   . LEU A 1 240 ? 113.386 138.362 89.214  1.00 56.71  ? 260 LEU A C   1 
ATOM   1664  O O   . LEU A 1 240 ? 114.142 138.421 90.182  1.00 57.65  ? 260 LEU A O   1 
ATOM   1665  C CB  . LEU A 1 240 ? 114.301 137.819 86.930  1.00 56.22  ? 260 LEU A CB  1 
ATOM   1666  C CG  . LEU A 1 240 ? 115.475 138.754 87.228  1.00 54.51  ? 260 LEU A CG  1 
ATOM   1667  C CD1 . LEU A 1 240 ? 116.583 138.032 87.985  1.00 54.17  ? 260 LEU A CD1 1 
ATOM   1668  C CD2 . LEU A 1 240 ? 116.015 139.359 85.944  1.00 54.06  ? 260 LEU A CD2 1 
ATOM   1669  N N   . LEU A 1 241 ? 112.391 139.231 89.022  1.00 56.63  ? 261 LEU A N   1 
ATOM   1670  C CA  . LEU A 1 241 ? 112.190 140.331 89.948  1.00 57.04  ? 261 LEU A CA  1 
ATOM   1671  C C   . LEU A 1 241 ? 111.642 139.815 91.278  1.00 59.25  ? 261 LEU A C   1 
ATOM   1672  O O   . LEU A 1 241 ? 111.964 140.370 92.318  1.00 59.71  ? 261 LEU A O   1 
ATOM   1673  C CB  . LEU A 1 241 ? 111.263 141.379 89.329  1.00 56.61  ? 261 LEU A CB  1 
ATOM   1674  C CG  . LEU A 1 241 ? 111.244 142.718 90.062  1.00 56.82  ? 261 LEU A CG  1 
ATOM   1675  C CD1 . LEU A 1 241 ? 112.580 143.435 89.917  1.00 56.19  ? 261 LEU A CD1 1 
ATOM   1676  C CD2 . LEU A 1 241 ? 110.122 143.589 89.536  1.00 57.38  ? 261 LEU A CD2 1 
ATOM   1677  N N   . LYS A 1 242 ? 110.830 138.751 91.247  1.00 61.96  ? 262 LYS A N   1 
ATOM   1678  C CA  . LYS A 1 242 ? 110.359 138.122 92.473  1.00 64.62  ? 262 LYS A CA  1 
ATOM   1679  C C   . LYS A 1 242 ? 111.544 137.567 93.263  1.00 64.64  ? 262 LYS A C   1 
ATOM   1680  O O   . LYS A 1 242 ? 111.604 137.720 94.479  1.00 64.81  ? 262 LYS A O   1 
ATOM   1681  C CB  . LYS A 1 242 ? 109.323 137.041 92.159  1.00 67.22  ? 262 LYS A CB  1 
ATOM   1682  C CG  . LYS A 1 242 ? 107.938 137.590 91.841  1.00 69.67  ? 262 LYS A CG  1 
ATOM   1683  C CD  . LYS A 1 242 ? 107.100 136.674 90.980  1.00 72.16  ? 262 LYS A CD  1 
ATOM   1684  C CE  . LYS A 1 242 ? 105.730 137.243 90.671  1.00 73.89  ? 262 LYS A CE  1 
ATOM   1685  N NZ  . LYS A 1 242 ? 104.952 137.509 91.904  1.00 74.79  ? 262 LYS A NZ  1 
ATOM   1686  N N   . LYS A 1 243 ? 112.489 136.927 92.565  1.00 64.75  ? 263 LYS A N   1 
ATOM   1687  C CA  . LYS A 1 243 ? 113.690 136.411 93.205  1.00 65.11  ? 263 LYS A CA  1 
ATOM   1688  C C   . LYS A 1 243 ? 114.524 137.561 93.772  1.00 63.34  ? 263 LYS A C   1 
ATOM   1689  O O   . LYS A 1 243 ? 115.115 137.422 94.840  1.00 63.79  ? 263 LYS A O   1 
ATOM   1690  C CB  . LYS A 1 243 ? 114.523 135.573 92.230  1.00 66.91  ? 263 LYS A CB  1 
ATOM   1691  C CG  . LYS A 1 243 ? 113.909 134.240 91.833  1.00 69.31  ? 263 LYS A CG  1 
ATOM   1692  C CD  . LYS A 1 243 ? 114.580 133.615 90.633  1.00 71.46  ? 263 LYS A CD  1 
ATOM   1693  C CE  . LYS A 1 243 ? 113.765 132.495 90.023  1.00 73.75  ? 263 LYS A CE  1 
ATOM   1694  N NZ  . LYS A 1 243 ? 114.435 131.922 88.832  1.00 75.08  ? 263 LYS A NZ  1 
ATOM   1695  N N   . LEU A 1 244 ? 114.573 138.694 93.059  1.00 62.45  ? 264 LEU A N   1 
ATOM   1696  C CA  . LEU A 1 244 ? 115.293 139.863 93.544  1.00 61.57  ? 264 LEU A CA  1 
ATOM   1697  C C   . LEU A 1 244 ? 114.649 140.375 94.832  1.00 64.92  ? 264 LEU A C   1 
ATOM   1698  O O   . LEU A 1 244 ? 115.355 140.781 95.751  1.00 67.17  ? 264 LEU A O   1 
ATOM   1699  C CB  . LEU A 1 244 ? 115.308 140.961 92.474  1.00 59.03  ? 264 LEU A CB  1 
ATOM   1700  C CG  . LEU A 1 244 ? 116.362 140.839 91.376  1.00 56.66  ? 264 LEU A CG  1 
ATOM   1701  C CD1 . LEU A 1 244 ? 116.255 142.003 90.407  1.00 55.72  ? 264 LEU A CD1 1 
ATOM   1702  C CD2 . LEU A 1 244 ? 117.760 140.792 91.961  1.00 55.68  ? 264 LEU A CD2 1 
ATOM   1703  N N   . THR A 1 245 ? 113.312 140.355 94.892  1.00 67.34  ? 265 THR A N   1 
ATOM   1704  C CA  . THR A 1 245 ? 112.580 140.837 96.053  1.00 70.20  ? 265 THR A CA  1 
ATOM   1705  C C   . THR A 1 245 ? 112.674 139.855 97.219  1.00 72.50  ? 265 THR A C   1 
ATOM   1706  O O   . THR A 1 245 ? 112.408 140.238 98.355  1.00 72.65  ? 265 THR A O   1 
ATOM   1707  C CB  . THR A 1 245 ? 111.109 141.103 95.718  1.00 71.82  ? 265 THR A CB  1 
ATOM   1708  O OG1 . THR A 1 245 ? 110.520 139.887 95.259  1.00 72.91  ? 265 THR A OG1 1 
ATOM   1709  C CG2 . THR A 1 245 ? 110.930 142.177 94.671  1.00 72.53  ? 265 THR A CG2 1 
ATOM   1710  N N   . SER A 1 246 ? 113.046 138.597 96.949  1.00 74.72  ? 266 SER A N   1 
ATOM   1711  C CA  . SER A 1 246 ? 113.199 137.609 98.007  1.00 76.68  ? 266 SER A CA  1 
ATOM   1712  C C   . SER A 1 246 ? 114.280 138.029 99.007  1.00 78.01  ? 266 SER A C   1 
ATOM   1713  O O   . SER A 1 246 ? 114.304 137.526 100.128 1.00 79.08  ? 266 SER A O   1 
ATOM   1714  C CB  . SER A 1 246 ? 113.483 136.239 97.444  1.00 77.73  ? 266 SER A CB  1 
ATOM   1715  O OG  . SER A 1 246 ? 114.816 136.144 96.962  1.00 78.45  ? 266 SER A OG  1 
ATOM   1716  N N   . HIS A 1 247 ? 115.188 138.925 98.588  1.00 80.94  ? 267 HIS A N   1 
ATOM   1717  C CA  . HIS A 1 247 ? 116.200 139.473 99.480  1.00 85.84  ? 267 HIS A CA  1 
ATOM   1718  C C   . HIS A 1 247 ? 116.064 140.993 99.563  1.00 87.19  ? 267 HIS A C   1 
ATOM   1719  O O   . HIS A 1 247 ? 117.069 141.698 99.604  1.00 86.61  ? 267 HIS A O   1 
ATOM   1720  C CB  . HIS A 1 247 ? 117.609 139.116 98.990  1.00 89.16  ? 267 HIS A CB  1 
ATOM   1721  C CG  . HIS A 1 247 ? 117.700 137.804 98.286  1.00 92.66  ? 267 HIS A CG  1 
ATOM   1722  N ND1 . HIS A 1 247 ? 117.665 136.571 98.898  1.00 96.11  ? 267 HIS A ND1 1 
ATOM   1723  C CD2 . HIS A 1 247 ? 117.805 137.571 96.978  1.00 93.75  ? 267 HIS A CD2 1 
ATOM   1724  C CE1 . HIS A 1 247 ? 117.761 135.627 97.972  1.00 97.39  ? 267 HIS A CE1 1 
ATOM   1725  N NE2 . HIS A 1 247 ? 117.843 136.212 96.798  1.00 95.91  ? 267 HIS A NE2 1 
ATOM   1726  N N   . LEU A 1 248 ? 114.826 141.497 99.613  1.00 90.50  ? 268 LEU A N   1 
ATOM   1727  C CA  . LEU A 1 248 ? 114.573 142.908 99.347  1.00 94.57  ? 268 LEU A CA  1 
ATOM   1728  C C   . LEU A 1 248 ? 115.066 143.785 100.500 1.00 96.16  ? 268 LEU A C   1 
ATOM   1729  O O   . LEU A 1 248 ? 115.839 144.710 100.265 1.00 95.96  ? 268 LEU A O   1 
ATOM   1730  C CB  . LEU A 1 248 ? 113.081 143.134 99.076  1.00 97.58  ? 268 LEU A CB  1 
ATOM   1731  C CG  . LEU A 1 248 ? 112.749 144.259 98.096  1.00 99.95  ? 268 LEU A CG  1 
ATOM   1732  C CD1 . LEU A 1 248 ? 111.264 144.264 97.770  1.00 102.87 ? 268 LEU A CD1 1 
ATOM   1733  C CD2 . LEU A 1 248 ? 113.172 145.616 98.636  1.00 99.33  ? 268 LEU A CD2 1 
ATOM   1734  N N   . PRO A 1 249 ? 114.654 143.558 101.771 1.00 96.66  ? 269 PRO A N   1 
ATOM   1735  C CA  . PRO A 1 249 ? 114.978 144.496 102.847 1.00 95.80  ? 269 PRO A CA  1 
ATOM   1736  C C   . PRO A 1 249 ? 116.476 144.739 103.027 1.00 92.93  ? 269 PRO A C   1 
ATOM   1737  O O   . PRO A 1 249 ? 116.875 145.831 103.427 1.00 91.96  ? 269 PRO A O   1 
ATOM   1738  C CB  . PRO A 1 249 ? 114.389 143.837 104.106 1.00 97.55  ? 269 PRO A CB  1 
ATOM   1739  C CG  . PRO A 1 249 ? 113.331 142.893 103.575 1.00 97.83  ? 269 PRO A CG  1 
ATOM   1740  C CD  . PRO A 1 249 ? 113.889 142.399 102.258 1.00 97.33  ? 269 PRO A CD  1 
ATOM   1741  N N   . LYS A 1 250 ? 117.294 143.723 102.712 1.00 90.13  ? 270 LYS A N   1 
ATOM   1742  C CA  . LYS A 1 250 ? 118.724 143.769 102.980 1.00 88.27  ? 270 LYS A CA  1 
ATOM   1743  C C   . LYS A 1 250 ? 119.502 144.121 101.712 1.00 83.00  ? 270 LYS A C   1 
ATOM   1744  O O   . LYS A 1 250 ? 120.244 145.096 101.703 1.00 83.30  ? 270 LYS A O   1 
ATOM   1745  C CB  . LYS A 1 250 ? 119.185 142.434 103.573 1.00 91.52  ? 270 LYS A CB  1 
ATOM   1746  C CG  . LYS A 1 250 ? 118.883 142.260 105.056 1.00 93.74  ? 270 LYS A CG  1 
ATOM   1747  C CD  . LYS A 1 250 ? 119.791 143.092 105.943 1.00 94.82  ? 270 LYS A CD  1 
ATOM   1748  C CE  . LYS A 1 250 ? 119.467 142.984 107.417 1.00 94.65  ? 270 LYS A CE  1 
ATOM   1749  N NZ  . LYS A 1 250 ? 120.556 143.547 108.250 1.00 93.90  ? 270 LYS A NZ  1 
ATOM   1750  N N   . ALA A 1 251 ? 119.313 143.337 100.644 1.00 77.21  ? 271 ALA A N   1 
ATOM   1751  C CA  . ALA A 1 251 ? 120.024 143.555 99.392  1.00 71.42  ? 271 ALA A CA  1 
ATOM   1752  C C   . ALA A 1 251 ? 119.250 144.535 98.511  1.00 66.75  ? 271 ALA A C   1 
ATOM   1753  O O   . ALA A 1 251 ? 118.361 144.134 97.763  1.00 66.27  ? 271 ALA A O   1 
ATOM   1754  C CB  . ALA A 1 251 ? 120.232 142.241 98.697  1.00 70.98  ? 271 ALA A CB  1 
ATOM   1755  N N   . ARG A 1 252 ? 119.595 145.822 98.620  1.00 63.85  ? 272 ARG A N   1 
ATOM   1756  C CA  . ARG A 1 252 ? 118.814 146.880 97.998  1.00 63.05  ? 272 ARG A CA  1 
ATOM   1757  C C   . ARG A 1 252 ? 119.482 147.367 96.714  1.00 57.43  ? 272 ARG A C   1 
ATOM   1758  O O   . ARG A 1 252 ? 118.854 148.072 95.923  1.00 57.09  ? 272 ARG A O   1 
ATOM   1759  C CB  . ARG A 1 252 ? 118.630 148.031 98.989  1.00 68.44  ? 272 ARG A CB  1 
ATOM   1760  C CG  . ARG A 1 252 ? 117.507 148.987 98.615  1.00 73.17  ? 272 ARG A CG  1 
ATOM   1761  C CD  . ARG A 1 252 ? 117.019 149.832 99.777  1.00 77.06  ? 272 ARG A CD  1 
ATOM   1762  N NE  . ARG A 1 252 ? 116.617 149.007 100.911 1.00 81.12  ? 272 ARG A NE  1 
ATOM   1763  C CZ  . ARG A 1 252 ? 115.364 148.696 101.233 1.00 85.20  ? 272 ARG A CZ  1 
ATOM   1764  N NH1 . ARG A 1 252 ? 114.348 149.170 100.532 1.00 85.81  ? 272 ARG A NH1 1 
ATOM   1765  N NH2 . ARG A 1 252 ? 115.130 147.911 102.273 1.00 86.32  ? 272 ARG A NH2 1 
ATOM   1766  N N   . VAL A 1 253 ? 120.755 146.998 96.515  1.00 52.27  ? 273 VAL A N   1 
ATOM   1767  C CA  . VAL A 1 253 ? 121.483 147.388 95.319  1.00 47.93  ? 273 VAL A CA  1 
ATOM   1768  C C   . VAL A 1 253 ? 121.640 146.165 94.422  1.00 45.16  ? 273 VAL A C   1 
ATOM   1769  O O   . VAL A 1 253 ? 122.167 145.138 94.852  1.00 44.19  ? 273 VAL A O   1 
ATOM   1770  C CB  . VAL A 1 253 ? 122.850 148.010 95.657  1.00 46.90  ? 273 VAL A CB  1 
ATOM   1771  C CG1 . VAL A 1 253 ? 123.666 148.267 94.400  1.00 46.90  ? 273 VAL A CG1 1 
ATOM   1772  C CG2 . VAL A 1 253 ? 122.704 149.287 96.466  1.00 46.37  ? 273 VAL A CG2 1 
ATOM   1773  N N   . VAL A 1 254 ? 121.196 146.309 93.168  1.00 44.05  ? 274 VAL A N   1 
ATOM   1774  C CA  . VAL A 1 254 ? 121.352 145.276 92.163  1.00 43.13  ? 274 VAL A CA  1 
ATOM   1775  C C   . VAL A 1 254 ? 122.389 145.741 91.145  1.00 42.15  ? 274 VAL A C   1 
ATOM   1776  O O   . VAL A 1 254 ? 122.120 146.638 90.348  1.00 42.74  ? 274 VAL A O   1 
ATOM   1777  C CB  . VAL A 1 254 ? 120.002 144.943 91.503  1.00 43.12  ? 274 VAL A CB  1 
ATOM   1778  C CG1 . VAL A 1 254 ? 120.147 144.110 90.238  1.00 43.32  ? 274 VAL A CG1 1 
ATOM   1779  C CG2 . VAL A 1 254 ? 119.077 144.249 92.487  1.00 43.77  ? 274 VAL A CG2 1 
ATOM   1780  N N   . ALA A 1 255 ? 123.570 145.116 91.187  1.00 40.67  ? 275 ALA A N   1 
ATOM   1781  C CA  . ALA A 1 255 ? 124.595 145.352 90.188  1.00 40.11  ? 275 ALA A CA  1 
ATOM   1782  C C   . ALA A 1 255 ? 124.187 144.648 88.900  1.00 39.82  ? 275 ALA A C   1 
ATOM   1783  O O   . ALA A 1 255 ? 124.106 143.422 88.860  1.00 40.34  ? 275 ALA A O   1 
ATOM   1784  C CB  . ALA A 1 255 ? 125.929 144.867 90.686  1.00 40.61  ? 275 ALA A CB  1 
ATOM   1785  N N   . CYS A 1 256 ? 123.913 145.443 87.862  1.00 39.29  ? 276 CYS A N   1 
ATOM   1786  C CA  . CYS A 1 256 ? 123.434 144.919 86.595  1.00 38.63  ? 276 CYS A CA  1 
ATOM   1787  C C   . CYS A 1 256 ? 124.558 145.034 85.571  1.00 37.92  ? 276 CYS A C   1 
ATOM   1788  O O   . CYS A 1 256 ? 124.883 146.137 85.131  1.00 38.16  ? 276 CYS A O   1 
ATOM   1789  C CB  . CYS A 1 256 ? 122.205 145.692 86.125  1.00 39.37  ? 276 CYS A CB  1 
ATOM   1790  S SG  . CYS A 1 256 ? 120.957 144.739 85.215  1.00 42.12  ? 276 CYS A SG  1 
ATOM   1791  N N   . PHE A 1 257 ? 125.162 143.892 85.217  1.00 36.81  ? 277 PHE A N   1 
ATOM   1792  C CA  . PHE A 1 257 ? 126.056 143.833 84.073  1.00 35.66  ? 277 PHE A CA  1 
ATOM   1793  C C   . PHE A 1 257 ? 125.245 143.426 82.848  1.00 34.81  ? 277 PHE A C   1 
ATOM   1794  O O   . PHE A 1 257 ? 125.532 142.436 82.184  1.00 34.59  ? 277 PHE A O   1 
ATOM   1795  C CB  . PHE A 1 257 ? 127.236 142.902 84.343  1.00 35.65  ? 277 PHE A CB  1 
ATOM   1796  C CG  . PHE A 1 257 ? 128.543 143.493 83.886  1.00 36.53  ? 277 PHE A CG  1 
ATOM   1797  C CD1 . PHE A 1 257 ? 128.819 143.648 82.534  1.00 37.06  ? 277 PHE A CD1 1 
ATOM   1798  C CD2 . PHE A 1 257 ? 129.457 143.981 84.805  1.00 36.48  ? 277 PHE A CD2 1 
ATOM   1799  C CE1 . PHE A 1 257 ? 130.017 144.208 82.114  1.00 36.86  ? 277 PHE A CE1 1 
ATOM   1800  C CE2 . PHE A 1 257 ? 130.657 144.534 84.384  1.00 36.52  ? 277 PHE A CE2 1 
ATOM   1801  C CZ  . PHE A 1 257 ? 130.928 144.661 83.041  1.00 36.66  ? 277 PHE A CZ  1 
ATOM   1802  N N   . CYS A 1 258 ? 124.229 144.236 82.559  1.00 34.79  ? 278 CYS A N   1 
ATOM   1803  C CA  . CYS A 1 258 ? 123.160 143.853 81.659  1.00 34.64  ? 278 CYS A CA  1 
ATOM   1804  C C   . CYS A 1 258 ? 123.164 144.778 80.451  1.00 33.65  ? 278 CYS A C   1 
ATOM   1805  O O   . CYS A 1 258 ? 123.762 145.851 80.486  1.00 33.47  ? 278 CYS A O   1 
ATOM   1806  C CB  . CYS A 1 258 ? 121.817 143.932 82.372  1.00 35.72  ? 278 CYS A CB  1 
ATOM   1807  S SG  . CYS A 1 258 ? 121.893 143.330 84.079  1.00 38.91  ? 278 CYS A SG  1 
ATOM   1808  N N   . GLU A 1 259 ? 122.466 144.346 79.399  1.00 33.18  ? 279 GLU A N   1 
ATOM   1809  C CA  . GLU A 1 259 ? 122.263 145.155 78.212  1.00 33.15  ? 279 GLU A CA  1 
ATOM   1810  C C   . GLU A 1 259 ? 121.131 146.141 78.469  1.00 32.91  ? 279 GLU A C   1 
ATOM   1811  O O   . GLU A 1 259 ? 120.543 146.154 79.547  1.00 33.43  ? 279 GLU A O   1 
ATOM   1812  C CB  . GLU A 1 259 ? 121.953 144.253 77.021  1.00 34.03  ? 279 GLU A CB  1 
ATOM   1813  C CG  . GLU A 1 259 ? 123.057 143.259 76.736  1.00 35.45  ? 279 GLU A CG  1 
ATOM   1814  C CD  . GLU A 1 259 ? 122.985 142.598 75.372  1.00 36.89  ? 279 GLU A CD  1 
ATOM   1815  O OE1 . GLU A 1 259 ? 122.069 142.931 74.588  1.00 37.37  ? 279 GLU A OE1 1 
ATOM   1816  O OE2 . GLU A 1 259 ? 123.853 141.755 75.097  1.00 37.42  ? 279 GLU A OE2 1 
ATOM   1817  N N   . GLY A 1 260 ? 120.835 146.971 77.466  1.00 33.14  ? 280 GLY A N   1 
ATOM   1818  C CA  . GLY A 1 260 ? 119.738 147.918 77.562  1.00 33.43  ? 280 GLY A CA  1 
ATOM   1819  C C   . GLY A 1 260 ? 118.395 147.214 77.729  1.00 33.93  ? 280 GLY A C   1 
ATOM   1820  O O   . GLY A 1 260 ? 117.568 147.637 78.529  1.00 34.61  ? 280 GLY A O   1 
ATOM   1821  N N   . MET A 1 261 ? 118.189 146.131 76.973  1.00 34.29  ? 281 MET A N   1 
ATOM   1822  C CA  . MET A 1 261 ? 116.899 145.467 76.935  1.00 34.61  ? 281 MET A CA  1 
ATOM   1823  C C   . MET A 1 261 ? 116.664 144.681 78.223  1.00 33.05  ? 281 MET A C   1 
ATOM   1824  O O   . MET A 1 261 ? 115.525 144.563 78.666  1.00 33.46  ? 281 MET A O   1 
ATOM   1825  C CB  . MET A 1 261 ? 116.796 144.534 75.725  1.00 36.54  ? 281 MET A CB  1 
ATOM   1826  C CG  . MET A 1 261 ? 116.619 145.277 74.410  1.00 38.60  ? 281 MET A CG  1 
ATOM   1827  S SD  . MET A 1 261 ? 115.427 146.643 74.514  1.00 41.49  ? 281 MET A SD  1 
ATOM   1828  C CE  . MET A 1 261 ? 116.517 148.060 74.664  1.00 41.52  ? 281 MET A CE  1 
ATOM   1829  N N   . THR A 1 262 ? 117.730 144.152 78.832  1.00 31.28  ? 282 THR A N   1 
ATOM   1830  C CA  . THR A 1 262 ? 117.589 143.458 80.101  1.00 30.45  ? 282 THR A CA  1 
ATOM   1831  C C   . THR A 1 262 ? 117.147 144.444 81.178  1.00 30.22  ? 282 THR A C   1 
ATOM   1832  O O   . THR A 1 262 ? 116.259 144.140 81.972  1.00 31.35  ? 282 THR A O   1 
ATOM   1833  C CB  . THR A 1 262 ? 118.892 142.765 80.512  1.00 30.23  ? 282 THR A CB  1 
ATOM   1834  O OG1 . THR A 1 262 ? 119.226 141.837 79.482  1.00 29.94  ? 282 THR A OG1 1 
ATOM   1835  C CG2 . THR A 1 262 ? 118.788 142.056 81.845  1.00 30.41  ? 282 THR A CG2 1 
ATOM   1836  N N   . VAL A 1 263 ? 117.785 145.618 81.209  1.00 29.20  ? 283 VAL A N   1 
ATOM   1837  C CA  . VAL A 1 263 ? 117.437 146.634 82.185  1.00 28.55  ? 283 VAL A CA  1 
ATOM   1838  C C   . VAL A 1 263 ? 115.998 147.079 81.945  1.00 28.89  ? 283 VAL A C   1 
ATOM   1839  O O   . VAL A 1 263 ? 115.245 147.256 82.901  1.00 29.80  ? 283 VAL A O   1 
ATOM   1840  C CB  . VAL A 1 263 ? 118.409 147.827 82.143  1.00 28.22  ? 283 VAL A CB  1 
ATOM   1841  C CG1 . VAL A 1 263 ? 117.854 149.034 82.885  1.00 28.33  ? 283 VAL A CG1 1 
ATOM   1842  C CG2 . VAL A 1 263 ? 119.778 147.451 82.680  1.00 28.13  ? 283 VAL A CG2 1 
ATOM   1843  N N   . ARG A 1 264 ? 115.626 147.264 80.673  1.00 29.04  ? 284 ARG A N   1 
ATOM   1844  C CA  . ARG A 1 264 ? 114.289 147.724 80.341  1.00 29.43  ? 284 ARG A CA  1 
ATOM   1845  C C   . ARG A 1 264 ? 113.270 146.676 80.773  1.00 30.02  ? 284 ARG A C   1 
ATOM   1846  O O   . ARG A 1 264 ? 112.205 147.033 81.262  1.00 31.13  ? 284 ARG A O   1 
ATOM   1847  C CB  . ARG A 1 264 ? 114.157 148.039 78.849  1.00 30.13  ? 284 ARG A CB  1 
ATOM   1848  C CG  . ARG A 1 264 ? 112.795 148.600 78.468  1.00 31.13  ? 284 ARG A CG  1 
ATOM   1849  C CD  . ARG A 1 264 ? 112.798 149.343 77.148  1.00 32.03  ? 284 ARG A CD  1 
ATOM   1850  N NE  . ARG A 1 264 ? 111.498 149.929 76.848  1.00 32.77  ? 284 ARG A NE  1 
ATOM   1851  C CZ  . ARG A 1 264 ? 110.974 151.000 77.442  1.00 33.75  ? 284 ARG A CZ  1 
ATOM   1852  N NH1 . ARG A 1 264 ? 111.641 151.660 78.377  1.00 33.87  ? 284 ARG A NH1 1 
ATOM   1853  N NH2 . ARG A 1 264 ? 109.781 151.433 77.067  1.00 34.50  ? 284 ARG A NH2 1 
ATOM   1854  N N   . GLY A 1 265 ? 113.604 145.392 80.595  1.00 30.81  ? 285 GLY A N   1 
ATOM   1855  C CA  . GLY A 1 265 ? 112.742 144.306 81.030  1.00 31.64  ? 285 GLY A CA  1 
ATOM   1856  C C   . GLY A 1 265 ? 112.522 144.323 82.539  1.00 31.99  ? 285 GLY A C   1 
ATOM   1857  O O   . GLY A 1 265 ? 111.406 144.121 83.004  1.00 32.40  ? 285 GLY A O   1 
ATOM   1858  N N   . LEU A 1 266 ? 113.594 144.579 83.295  1.00 32.69  ? 286 LEU A N   1 
ATOM   1859  C CA  . LEU A 1 266 ? 113.492 144.700 84.739  1.00 33.46  ? 286 LEU A CA  1 
ATOM   1860  C C   . LEU A 1 266 ? 112.620 145.892 85.127  1.00 33.90  ? 286 LEU A C   1 
ATOM   1861  O O   . LEU A 1 266 ? 111.841 145.795 86.073  1.00 35.27  ? 286 LEU A O   1 
ATOM   1862  C CB  . LEU A 1 266 ? 114.896 144.815 85.340  1.00 34.62  ? 286 LEU A CB  1 
ATOM   1863  C CG  . LEU A 1 266 ? 115.548 143.485 85.710  1.00 35.51  ? 286 LEU A CG  1 
ATOM   1864  C CD1 . LEU A 1 266 ? 116.960 143.698 86.235  1.00 35.48  ? 286 LEU A CD1 1 
ATOM   1865  C CD2 . LEU A 1 266 ? 114.705 142.748 86.741  1.00 36.19  ? 286 LEU A CD2 1 
ATOM   1866  N N   . LEU A 1 267 ? 112.732 147.005 84.391  1.00 33.77  ? 287 LEU A N   1 
ATOM   1867  C CA  . LEU A 1 267 ? 111.928 148.183 84.681  1.00 33.98  ? 287 LEU A CA  1 
ATOM   1868  C C   . LEU A 1 267 ? 110.451 147.901 84.409  1.00 35.89  ? 287 LEU A C   1 
ATOM   1869  O O   . LEU A 1 267 ? 109.587 148.302 85.185  1.00 37.17  ? 287 LEU A O   1 
ATOM   1870  C CB  . LEU A 1 267 ? 112.429 149.362 83.844  1.00 33.14  ? 287 LEU A CB  1 
ATOM   1871  C CG  . LEU A 1 267 ? 113.857 149.821 84.135  1.00 32.72  ? 287 LEU A CG  1 
ATOM   1872  C CD1 . LEU A 1 267 ? 114.147 151.146 83.451  1.00 32.89  ? 287 LEU A CD1 1 
ATOM   1873  C CD2 . LEU A 1 267 ? 114.114 149.929 85.629  1.00 32.70  ? 287 LEU A CD2 1 
ATOM   1874  N N   . MET A 1 268 ? 110.157 147.202 83.311  1.00 37.83  ? 288 MET A N   1 
ATOM   1875  C CA  . MET A 1 268 ? 108.782 146.869 82.979  1.00 40.10  ? 288 MET A CA  1 
ATOM   1876  C C   . MET A 1 268 ? 108.218 145.902 84.022  1.00 41.32  ? 288 MET A C   1 
ATOM   1877  O O   . MET A 1 268 ? 107.049 146.000 84.391  1.00 42.92  ? 288 MET A O   1 
ATOM   1878  C CB  . MET A 1 268 ? 108.695 146.258 81.577  1.00 41.96  ? 288 MET A CB  1 
ATOM   1879  C CG  . MET A 1 268 ? 109.300 147.159 80.510  1.00 43.63  ? 288 MET A CG  1 
ATOM   1880  S SD  . MET A 1 268 ? 108.534 147.012 78.883  1.00 47.00  ? 288 MET A SD  1 
ATOM   1881  C CE  . MET A 1 268 ? 108.616 145.236 78.655  1.00 47.24  ? 288 MET A CE  1 
ATOM   1882  N N   . ALA A 1 269 ? 109.056 144.987 84.523  1.00 41.91  ? 289 ALA A N   1 
ATOM   1883  C CA  . ALA A 1 269 ? 108.634 144.077 85.576  1.00 42.87  ? 289 ALA A CA  1 
ATOM   1884  C C   . ALA A 1 269 ? 108.301 144.867 86.837  1.00 43.96  ? 289 ALA A C   1 
ATOM   1885  O O   . ALA A 1 269 ? 107.323 144.557 87.506  1.00 46.10  ? 289 ALA A O   1 
ATOM   1886  C CB  . ALA A 1 269 ? 109.688 143.029 85.843  1.00 43.56  ? 289 ALA A CB  1 
ATOM   1887  N N   . MET A 1 270 ? 109.112 145.883 87.155  1.00 44.42  ? 290 MET A N   1 
ATOM   1888  C CA  . MET A 1 270 ? 108.865 146.701 88.330  1.00 45.70  ? 290 MET A CA  1 
ATOM   1889  C C   . MET A 1 270 ? 107.531 147.429 88.178  1.00 48.68  ? 290 MET A C   1 
ATOM   1890  O O   . MET A 1 270 ? 106.802 147.583 89.157  1.00 50.67  ? 290 MET A O   1 
ATOM   1891  C CB  . MET A 1 270 ? 109.984 147.721 88.550  1.00 45.63  ? 290 MET A CB  1 
ATOM   1892  C CG  . MET A 1 270 ? 111.281 147.108 89.019  1.00 46.55  ? 290 MET A CG  1 
ATOM   1893  S SD  . MET A 1 270 ? 112.625 148.322 88.980  1.00 47.96  ? 290 MET A SD  1 
ATOM   1894  C CE  . MET A 1 270 ? 113.954 147.382 89.728  1.00 48.28  ? 290 MET A CE  1 
ATOM   1895  N N   . ARG A 1 271 ? 107.208 147.850 86.947  1.00 51.52  ? 291 ARG A N   1 
ATOM   1896  C CA  . ARG A 1 271 ? 105.935 148.501 86.676  1.00 54.19  ? 291 ARG A CA  1 
ATOM   1897  C C   . ARG A 1 271 ? 104.788 147.528 86.933  1.00 55.54  ? 291 ARG A C   1 
ATOM   1898  O O   . ARG A 1 271 ? 103.790 147.901 87.544  1.00 56.96  ? 291 ARG A O   1 
ATOM   1899  C CB  . ARG A 1 271 ? 105.868 149.018 85.233  1.00 55.83  ? 291 ARG A CB  1 
ATOM   1900  C CG  . ARG A 1 271 ? 104.497 149.522 84.804  1.00 57.81  ? 291 ARG A CG  1 
ATOM   1901  C CD  . ARG A 1 271 ? 104.029 150.722 85.606  1.00 59.36  ? 291 ARG A CD  1 
ATOM   1902  N NE  . ARG A 1 271 ? 104.905 151.875 85.442  1.00 60.55  ? 291 ARG A NE  1 
ATOM   1903  C CZ  . ARG A 1 271 ? 105.062 152.566 84.314  1.00 62.82  ? 291 ARG A CZ  1 
ATOM   1904  N NH1 . ARG A 1 271 ? 104.376 152.251 83.227  1.00 63.33  ? 291 ARG A NH1 1 
ATOM   1905  N NH2 . ARG A 1 271 ? 105.905 153.585 84.278  1.00 63.54  ? 291 ARG A NH2 1 
ATOM   1906  N N   . ARG A 1 272 ? 104.933 146.291 86.448  1.00 56.98  ? 292 ARG A N   1 
ATOM   1907  C CA  . ARG A 1 272 ? 103.834 145.339 86.455  1.00 59.80  ? 292 ARG A CA  1 
ATOM   1908  C C   . ARG A 1 272 ? 103.453 144.957 87.884  1.00 62.10  ? 292 ARG A C   1 
ATOM   1909  O O   . ARG A 1 272 ? 102.269 144.905 88.212  1.00 63.33  ? 292 ARG A O   1 
ATOM   1910  C CB  . ARG A 1 272 ? 104.187 144.086 85.651  1.00 60.66  ? 292 ARG A CB  1 
ATOM   1911  C CG  . ARG A 1 272 ? 103.981 144.226 84.150  1.00 61.43  ? 292 ARG A CG  1 
ATOM   1912  C CD  . ARG A 1 272 ? 103.981 142.872 83.465  1.00 61.64  ? 292 ARG A CD  1 
ATOM   1913  N NE  . ARG A 1 272 ? 105.288 142.232 83.488  1.00 61.60  ? 292 ARG A NE  1 
ATOM   1914  C CZ  . ARG A 1 272 ? 106.308 142.535 82.690  1.00 61.48  ? 292 ARG A CZ  1 
ATOM   1915  N NH1 . ARG A 1 272 ? 106.160 143.404 81.705  1.00 61.28  ? 292 ARG A NH1 1 
ATOM   1916  N NH2 . ARG A 1 272 ? 107.478 141.947 82.869  1.00 61.47  ? 292 ARG A NH2 1 
ATOM   1917  N N   . LEU A 1 273 ? 104.465 144.706 88.724  1.00 64.25  ? 293 LEU A N   1 
ATOM   1918  C CA  . LEU A 1 273 ? 104.284 144.146 90.053  1.00 67.34  ? 293 LEU A CA  1 
ATOM   1919  C C   . LEU A 1 273 ? 104.394 145.230 91.127  1.00 68.82  ? 293 LEU A C   1 
ATOM   1920  O O   . LEU A 1 273 ? 104.437 144.903 92.311  1.00 69.44  ? 293 LEU A O   1 
ATOM   1921  C CB  . LEU A 1 273 ? 105.359 143.072 90.269  1.00 68.64  ? 293 LEU A CB  1 
ATOM   1922  C CG  . LEU A 1 273 ? 105.593 142.095 89.113  1.00 70.01  ? 293 LEU A CG  1 
ATOM   1923  C CD1 . LEU A 1 273 ? 106.707 141.110 89.443  1.00 69.86  ? 293 LEU A CD1 1 
ATOM   1924  C CD2 . LEU A 1 273 ? 104.316 141.346 88.758  1.00 71.28  ? 293 LEU A CD2 1 
ATOM   1925  N N   . GLY A 1 274 ? 104.443 146.506 90.711  1.00 70.15  ? 294 GLY A N   1 
ATOM   1926  C CA  . GLY A 1 274 ? 104.433 147.639 91.625  1.00 72.02  ? 294 GLY A CA  1 
ATOM   1927  C C   . GLY A 1 274 ? 105.647 147.666 92.550  1.00 73.61  ? 294 GLY A C   1 
ATOM   1928  O O   . GLY A 1 274 ? 105.492 147.524 93.762  1.00 74.57  ? 294 GLY A O   1 
ATOM   1929  N N   . LEU A 1 275 ? 106.844 147.803 91.961  1.00 75.07  ? 295 LEU A N   1 
ATOM   1930  C CA  . LEU A 1 275 ? 108.093 147.853 92.705  1.00 75.66  ? 295 LEU A CA  1 
ATOM   1931  C C   . LEU A 1 275 ? 108.881 149.090 92.284  1.00 75.20  ? 295 LEU A C   1 
ATOM   1932  O O   . LEU A 1 275 ? 110.107 149.053 92.213  1.00 74.45  ? 295 LEU A O   1 
ATOM   1933  C CB  . LEU A 1 275 ? 108.908 146.586 92.421  1.00 76.87  ? 295 LEU A CB  1 
ATOM   1934  C CG  . LEU A 1 275 ? 108.362 145.275 92.984  1.00 78.52  ? 295 LEU A CG  1 
ATOM   1935  C CD1 . LEU A 1 275 ? 109.252 144.114 92.581  1.00 79.16  ? 295 LEU A CD1 1 
ATOM   1936  C CD2 . LEU A 1 275 ? 108.222 145.330 94.498  1.00 79.51  ? 295 LEU A CD2 1 
ATOM   1937  N N   . ALA A 1 276 ? 108.170 150.188 92.014  1.00 75.99  ? 296 ALA A N   1 
ATOM   1938  C CA  . ALA A 1 276 ? 108.800 151.414 91.551  1.00 77.19  ? 296 ALA A CA  1 
ATOM   1939  C C   . ALA A 1 276 ? 109.417 152.167 92.730  1.00 76.83  ? 296 ALA A C   1 
ATOM   1940  O O   . ALA A 1 276 ? 108.723 152.937 93.390  1.00 76.66  ? 296 ALA A O   1 
ATOM   1941  C CB  . ALA A 1 276 ? 107.781 152.257 90.823  1.00 77.65  ? 296 ALA A CB  1 
ATOM   1942  N N   . GLY A 1 277 ? 110.711 151.925 92.984  1.00 75.97  ? 297 GLY A N   1 
ATOM   1943  C CA  . GLY A 1 277 ? 111.533 152.842 93.757  1.00 75.58  ? 297 GLY A CA  1 
ATOM   1944  C C   . GLY A 1 277 ? 111.962 152.285 95.113  1.00 75.22  ? 297 GLY A C   1 
ATOM   1945  O O   . GLY A 1 277 ? 111.946 153.013 96.105  1.00 76.40  ? 297 GLY A O   1 
ATOM   1946  N N   . GLU A 1 278 ? 112.341 151.003 95.151  1.00 73.62  ? 298 GLU A N   1 
ATOM   1947  C CA  . GLU A 1 278 ? 112.999 150.449 96.326  1.00 72.63  ? 298 GLU A CA  1 
ATOM   1948  C C   . GLU A 1 278 ? 114.191 149.584 95.923  1.00 68.17  ? 298 GLU A C   1 
ATOM   1949  O O   . GLU A 1 278 ? 114.812 148.995 96.801  1.00 68.06  ? 298 GLU A O   1 
ATOM   1950  C CB  . GLU A 1 278 ? 112.027 149.665 97.215  1.00 75.82  ? 298 GLU A CB  1 
ATOM   1951  C CG  . GLU A 1 278 ? 111.577 148.342 96.627  1.00 78.06  ? 298 GLU A CG  1 
ATOM   1952  C CD  . GLU A 1 278 ? 110.878 148.483 95.288  1.00 80.08  ? 298 GLU A CD  1 
ATOM   1953  O OE1 . GLU A 1 278 ? 110.822 147.484 94.557  1.00 80.84  ? 298 GLU A OE1 1 
ATOM   1954  O OE2 . GLU A 1 278 ? 110.400 149.598 94.984  1.00 80.10  ? 298 GLU A OE2 1 
ATOM   1955  N N   . PHE A 1 279 ? 114.500 149.506 94.621  1.00 64.68  ? 299 PHE A N   1 
ATOM   1956  C CA  . PHE A 1 279 ? 115.768 148.955 94.166  1.00 61.77  ? 299 PHE A CA  1 
ATOM   1957  C C   . PHE A 1 279 ? 116.622 150.054 93.544  1.00 56.82  ? 299 PHE A C   1 
ATOM   1958  O O   . PHE A 1 279 ? 116.105 150.938 92.864  1.00 55.09  ? 299 PHE A O   1 
ATOM   1959  C CB  . PHE A 1 279 ? 115.558 147.811 93.168  1.00 62.80  ? 299 PHE A CB  1 
ATOM   1960  C CG  . PHE A 1 279 ? 115.346 146.452 93.785  1.00 63.93  ? 299 PHE A CG  1 
ATOM   1961  C CD1 . PHE A 1 279 ? 115.699 146.187 95.103  1.00 66.75  ? 299 PHE A CD1 1 
ATOM   1962  C CD2 . PHE A 1 279 ? 114.777 145.430 93.043  1.00 64.46  ? 299 PHE A CD2 1 
ATOM   1963  C CE1 . PHE A 1 279 ? 115.499 144.930 95.654  1.00 69.08  ? 299 PHE A CE1 1 
ATOM   1964  C CE2 . PHE A 1 279 ? 114.575 144.174 93.596  1.00 66.75  ? 299 PHE A CE2 1 
ATOM   1965  C CZ  . PHE A 1 279 ? 114.935 143.932 94.899  1.00 68.59  ? 299 PHE A CZ  1 
ATOM   1966  N N   . LEU A 1 280 ? 117.930 149.983 93.811  1.00 53.22  ? 300 LEU A N   1 
ATOM   1967  C CA  . LEU A 1 280 ? 118.908 150.804 93.122  1.00 51.19  ? 300 LEU A CA  1 
ATOM   1968  C C   . LEU A 1 280 ? 119.626 149.933 92.095  1.00 49.64  ? 300 LEU A C   1 
ATOM   1969  O O   . LEU A 1 280 ? 120.250 148.938 92.457  1.00 49.25  ? 300 LEU A O   1 
ATOM   1970  C CB  . LEU A 1 280 ? 119.884 151.403 94.142  1.00 50.61  ? 300 LEU A CB  1 
ATOM   1971  C CG  . LEU A 1 280 ? 121.104 152.121 93.566  1.00 49.95  ? 300 LEU A CG  1 
ATOM   1972  C CD1 . LEU A 1 280 ? 120.694 153.164 92.546  1.00 49.10  ? 300 LEU A CD1 1 
ATOM   1973  C CD2 . LEU A 1 280 ? 121.919 152.776 94.665  1.00 50.81  ? 300 LEU A CD2 1 
ATOM   1974  N N   . LEU A 1 281 ? 119.510 150.313 90.818  1.00 47.73  ? 301 LEU A N   1 
ATOM   1975  C CA  . LEU A 1 281 ? 120.121 149.561 89.735  1.00 46.31  ? 301 LEU A CA  1 
ATOM   1976  C C   . LEU A 1 281 ? 121.461 150.191 89.374  1.00 43.83  ? 301 LEU A C   1 
ATOM   1977  O O   . LEU A 1 281 ? 121.500 151.288 88.821  1.00 43.84  ? 301 LEU A O   1 
ATOM   1978  C CB  . LEU A 1 281 ? 119.178 149.553 88.527  1.00 47.10  ? 301 LEU A CB  1 
ATOM   1979  C CG  . LEU A 1 281 ? 117.884 148.753 88.677  1.00 48.13  ? 301 LEU A CG  1 
ATOM   1980  C CD1 . LEU A 1 281 ? 117.149 148.682 87.347  1.00 48.25  ? 301 LEU A CD1 1 
ATOM   1981  C CD2 . LEU A 1 281 ? 118.151 147.349 89.211  1.00 48.02  ? 301 LEU A CD2 1 
ATOM   1982  N N   . LEU A 1 282 ? 122.554 149.489 89.696  1.00 41.29  ? 302 LEU A N   1 
ATOM   1983  C CA  . LEU A 1 282 ? 123.877 149.898 89.252  1.00 39.64  ? 302 LEU A CA  1 
ATOM   1984  C C   . LEU A 1 282 ? 124.150 149.261 87.892  1.00 38.09  ? 302 LEU A C   1 
ATOM   1985  O O   . LEU A 1 282 ? 124.484 148.081 87.808  1.00 38.53  ? 302 LEU A O   1 
ATOM   1986  C CB  . LEU A 1 282 ? 124.921 149.484 90.293  1.00 39.76  ? 302 LEU A CB  1 
ATOM   1987  C CG  . LEU A 1 282 ? 126.364 149.872 89.976  1.00 39.44  ? 302 LEU A CG  1 
ATOM   1988  C CD1 . LEU A 1 282 ? 126.612 151.349 90.239  1.00 39.29  ? 302 LEU A CD1 1 
ATOM   1989  C CD2 . LEU A 1 282 ? 127.328 149.021 90.784  1.00 39.31  ? 302 LEU A CD2 1 
ATOM   1990  N N   . GLY A 1 283 ? 124.004 150.065 86.834  1.00 36.36  ? 303 GLY A N   1 
ATOM   1991  C CA  . GLY A 1 283 ? 124.075 149.572 85.469  1.00 35.10  ? 303 GLY A CA  1 
ATOM   1992  C C   . GLY A 1 283 ? 125.510 149.436 84.966  1.00 33.68  ? 303 GLY A C   1 
ATOM   1993  O O   . GLY A 1 283 ? 126.458 149.477 85.742  1.00 33.29  ? 303 GLY A O   1 
ATOM   1994  N N   . SER A 1 284 ? 125.633 149.273 83.646  1.00 32.89  ? 304 SER A N   1 
ATOM   1995  C CA  . SER A 1 284 ? 126.911 149.190 82.959  1.00 32.20  ? 304 SER A CA  1 
ATOM   1996  C C   . SER A 1 284 ? 126.803 149.933 81.629  1.00 32.18  ? 304 SER A C   1 
ATOM   1997  O O   . SER A 1 284 ? 125.907 150.750 81.451  1.00 32.54  ? 304 SER A O   1 
ATOM   1998  C CB  . SER A 1 284 ? 127.314 147.756 82.765  1.00 32.00  ? 304 SER A CB  1 
ATOM   1999  O OG  . SER A 1 284 ? 127.354 147.073 84.003  1.00 32.47  ? 304 SER A OG  1 
ATOM   2000  N N   . ASP A 1 285 ? 127.704 149.641 80.687  1.00 32.17  ? 305 ASP A N   1 
ATOM   2001  C CA  . ASP A 1 285 ? 127.706 150.332 79.410  1.00 32.61  ? 305 ASP A CA  1 
ATOM   2002  C C   . ASP A 1 285 ? 126.476 149.957 78.588  1.00 31.83  ? 305 ASP A C   1 
ATOM   2003  O O   . ASP A 1 285 ? 126.149 150.651 77.627  1.00 32.50  ? 305 ASP A O   1 
ATOM   2004  C CB  . ASP A 1 285 ? 128.986 150.058 78.619  1.00 34.50  ? 305 ASP A CB  1 
ATOM   2005  C CG  . ASP A 1 285 ? 129.328 151.158 77.625  1.00 36.23  ? 305 ASP A CG  1 
ATOM   2006  O OD1 . ASP A 1 285 ? 128.591 152.173 77.578  1.00 36.25  ? 305 ASP A OD1 1 
ATOM   2007  O OD2 . ASP A 1 285 ? 130.323 150.991 76.892  1.00 37.36  ? 305 ASP A OD2 1 
ATOM   2008  N N   . GLY A 1 286 ? 125.828 148.833 78.910  1.00 30.57  ? 306 GLY A N   1 
ATOM   2009  C CA  . GLY A 1 286 ? 124.571 148.480 78.267  1.00 29.60  ? 306 GLY A CA  1 
ATOM   2010  C C   . GLY A 1 286 ? 123.507 149.548 78.498  1.00 28.84  ? 306 GLY A C   1 
ATOM   2011  O O   . GLY A 1 286 ? 122.804 149.953 77.573  1.00 29.39  ? 306 GLY A O   1 
ATOM   2012  N N   . TRP A 1 287 ? 123.388 149.991 79.751  1.00 27.99  ? 307 TRP A N   1 
ATOM   2013  C CA  . TRP A 1 287 ? 122.417 151.008 80.111  1.00 27.71  ? 307 TRP A CA  1 
ATOM   2014  C C   . TRP A 1 287 ? 122.958 152.385 79.731  1.00 28.19  ? 307 TRP A C   1 
ATOM   2015  O O   . TRP A 1 287 ? 122.352 153.084 78.925  1.00 28.50  ? 307 TRP A O   1 
ATOM   2016  C CB  . TRP A 1 287 ? 122.073 150.893 81.598  1.00 27.43  ? 307 TRP A CB  1 
ATOM   2017  C CG  . TRP A 1 287 ? 121.017 151.837 82.083  1.00 27.60  ? 307 TRP A CG  1 
ATOM   2018  C CD1 . TRP A 1 287 ? 120.405 152.843 81.393  1.00 27.64  ? 307 TRP A CD1 1 
ATOM   2019  C CD2 . TRP A 1 287 ? 120.451 151.860 83.401  1.00 28.01  ? 307 TRP A CD2 1 
ATOM   2020  N NE1 . TRP A 1 287 ? 119.499 153.487 82.188  1.00 27.81  ? 307 TRP A NE1 1 
ATOM   2021  C CE2 . TRP A 1 287 ? 119.503 152.905 83.426  1.00 28.10  ? 307 TRP A CE2 1 
ATOM   2022  C CE3 . TRP A 1 287 ? 120.657 151.101 84.557  1.00 28.48  ? 307 TRP A CE3 1 
ATOM   2023  C CZ2 . TRP A 1 287 ? 118.759 153.204 84.566  1.00 28.65  ? 307 TRP A CZ2 1 
ATOM   2024  C CZ3 . TRP A 1 287 ? 119.918 151.394 85.681  1.00 28.93  ? 307 TRP A CZ3 1 
ATOM   2025  C CH2 . TRP A 1 287 ? 118.985 152.433 85.684  1.00 29.02  ? 307 TRP A CH2 1 
ATOM   2026  N N   . ALA A 1 288 ? 124.093 152.774 80.326  1.00 28.58  ? 308 ALA A N   1 
ATOM   2027  C CA  . ALA A 1 288 ? 124.777 154.012 79.986  1.00 29.27  ? 308 ALA A CA  1 
ATOM   2028  C C   . ALA A 1 288 ? 123.815 155.200 80.066  1.00 30.64  ? 308 ALA A C   1 
ATOM   2029  O O   . ALA A 1 288 ? 123.225 155.433 81.113  1.00 30.83  ? 308 ALA A O   1 
ATOM   2030  C CB  . ALA A 1 288 ? 125.430 153.869 78.632  1.00 29.52  ? 308 ALA A CB  1 
ATOM   2031  N N   . ASP A 1 289 ? 123.653 155.926 78.950  1.00 32.97  ? 309 ASP A N   1 
ATOM   2032  C CA  . ASP A 1 289 ? 122.961 157.200 78.886  1.00 34.79  ? 309 ASP A CA  1 
ATOM   2033  C C   . ASP A 1 289 ? 121.611 157.032 78.181  1.00 36.73  ? 309 ASP A C   1 
ATOM   2034  O O   . ASP A 1 289 ? 120.879 157.998 78.001  1.00 37.17  ? 309 ASP A O   1 
ATOM   2035  C CB  . ASP A 1 289 ? 123.900 158.160 78.154  1.00 36.03  ? 309 ASP A CB  1 
ATOM   2036  C CG  . ASP A 1 289 ? 123.354 159.532 77.824  1.00 38.58  ? 309 ASP A CG  1 
ATOM   2037  O OD1 . ASP A 1 289 ? 122.522 159.628 76.899  1.00 40.19  ? 309 ASP A OD1 1 
ATOM   2038  O OD2 . ASP A 1 289 ? 123.786 160.492 78.480  1.00 40.15  ? 309 ASP A OD2 1 
ATOM   2039  N N   . ARG A 1 290 ? 121.249 155.792 77.830  1.00 39.44  ? 310 ARG A N   1 
ATOM   2040  C CA  . ARG A 1 290 ? 120.174 155.544 76.881  1.00 42.10  ? 310 ARG A CA  1 
ATOM   2041  C C   . ARG A 1 290 ? 118.841 156.057 77.412  1.00 43.96  ? 310 ARG A C   1 
ATOM   2042  O O   . ARG A 1 290 ? 118.464 155.766 78.544  1.00 44.50  ? 310 ARG A O   1 
ATOM   2043  C CB  . ARG A 1 290 ? 120.031 154.051 76.599  1.00 43.51  ? 310 ARG A CB  1 
ATOM   2044  C CG  . ARG A 1 290 ? 121.319 153.432 76.106  1.00 45.28  ? 310 ARG A CG  1 
ATOM   2045  C CD  . ARG A 1 290 ? 121.115 152.161 75.327  1.00 48.19  ? 310 ARG A CD  1 
ATOM   2046  N NE  . ARG A 1 290 ? 122.423 151.874 74.780  1.00 52.89  ? 310 ARG A NE  1 
ATOM   2047  C CZ  . ARG A 1 290 ? 123.108 152.708 73.995  1.00 57.85  ? 310 ARG A CZ  1 
ATOM   2048  N NH1 . ARG A 1 290 ? 122.514 153.749 73.430  1.00 59.33  ? 310 ARG A NH1 1 
ATOM   2049  N NH2 . ARG A 1 290 ? 124.387 152.485 73.746  1.00 57.24  ? 310 ARG A NH2 1 
ATOM   2050  N N   . TYR A 1 291 ? 118.126 156.800 76.561  1.00 45.51  ? 311 TYR A N   1 
ATOM   2051  C CA  . TYR A 1 291 ? 116.784 157.255 76.873  1.00 47.70  ? 311 TYR A CA  1 
ATOM   2052  C C   . TYR A 1 291 ? 115.753 156.198 76.485  1.00 48.43  ? 311 TYR A C   1 
ATOM   2053  O O   . TYR A 1 291 ? 114.636 156.225 77.000  1.00 50.06  ? 311 TYR A O   1 
ATOM   2054  C CB  . TYR A 1 291 ? 116.520 158.606 76.203  1.00 49.92  ? 311 TYR A CB  1 
ATOM   2055  C CG  . TYR A 1 291 ? 117.135 159.761 76.953  1.00 53.01  ? 311 TYR A CG  1 
ATOM   2056  C CD1 . TYR A 1 291 ? 116.789 159.995 78.274  1.00 54.73  ? 311 TYR A CD1 1 
ATOM   2057  C CD2 . TYR A 1 291 ? 118.084 160.592 76.375  1.00 54.59  ? 311 TYR A CD2 1 
ATOM   2058  C CE1 . TYR A 1 291 ? 117.337 161.045 78.991  1.00 55.64  ? 311 TYR A CE1 1 
ATOM   2059  C CE2 . TYR A 1 291 ? 118.655 161.636 77.085  1.00 55.77  ? 311 TYR A CE2 1 
ATOM   2060  C CZ  . TYR A 1 291 ? 118.282 161.862 78.399  1.00 56.65  ? 311 TYR A CZ  1 
ATOM   2061  O OH  . TYR A 1 291 ? 118.826 162.887 79.130  1.00 58.31  ? 311 TYR A OH  1 
ATOM   2062  N N   . ASP A 1 292 ? 116.123 155.283 75.580  1.00 47.64  ? 312 ASP A N   1 
ATOM   2063  C CA  . ASP A 1 292 ? 115.178 154.311 75.057  1.00 47.19  ? 312 ASP A CA  1 
ATOM   2064  C C   . ASP A 1 292 ? 115.004 153.152 76.036  1.00 43.94  ? 312 ASP A C   1 
ATOM   2065  O O   . ASP A 1 292 ? 114.084 152.352 75.876  1.00 43.62  ? 312 ASP A O   1 
ATOM   2066  C CB  . ASP A 1 292 ? 115.607 153.800 73.682  1.00 49.32  ? 312 ASP A CB  1 
ATOM   2067  C CG  . ASP A 1 292 ? 116.888 152.989 73.715  1.00 50.91  ? 312 ASP A CG  1 
ATOM   2068  O OD1 . ASP A 1 292 ? 116.895 151.925 74.372  1.00 51.58  ? 312 ASP A OD1 1 
ATOM   2069  O OD2 . ASP A 1 292 ? 117.863 153.427 73.078  1.00 51.32  ? 312 ASP A OD2 1 
ATOM   2070  N N   . VAL A 1 293 ? 115.886 153.043 77.036  1.00 40.99  ? 313 VAL A N   1 
ATOM   2071  C CA  . VAL A 1 293 ? 115.747 152.000 78.041  1.00 40.02  ? 313 VAL A CA  1 
ATOM   2072  C C   . VAL A 1 293 ? 114.903 152.492 79.215  1.00 39.79  ? 313 VAL A C   1 
ATOM   2073  O O   . VAL A 1 293 ? 114.425 151.677 80.000  1.00 39.63  ? 313 VAL A O   1 
ATOM   2074  C CB  . VAL A 1 293 ? 117.110 151.485 78.537  1.00 39.48  ? 313 VAL A CB  1 
ATOM   2075  C CG1 . VAL A 1 293 ? 117.953 150.943 77.397  1.00 40.00  ? 313 VAL A CG1 1 
ATOM   2076  C CG2 . VAL A 1 293 ? 117.869 152.544 79.314  1.00 39.50  ? 313 VAL A CG2 1 
ATOM   2077  N N   . THR A 1 294 ? 114.735 153.813 79.352  1.00 40.07  ? 314 THR A N   1 
ATOM   2078  C CA  . THR A 1 294 ? 114.006 154.360 80.485  1.00 40.74  ? 314 THR A CA  1 
ATOM   2079  C C   . THR A 1 294 ? 112.848 155.258 80.052  1.00 44.54  ? 314 THR A C   1 
ATOM   2080  O O   . THR A 1 294 ? 112.178 155.836 80.908  1.00 46.17  ? 314 THR A O   1 
ATOM   2081  C CB  . THR A 1 294 ? 114.947 155.126 81.420  1.00 38.69  ? 314 THR A CB  1 
ATOM   2082  O OG1 . THR A 1 294 ? 115.711 156.037 80.632  1.00 38.55  ? 314 THR A OG1 1 
ATOM   2083  C CG2 . THR A 1 294 ? 115.858 154.207 82.200  1.00 37.60  ? 314 THR A CG2 1 
ATOM   2084  N N   . ASP A 1 295 ? 112.580 155.361 78.746  1.00 47.57  ? 315 ASP A N   1 
ATOM   2085  C CA  . ASP A 1 295 ? 111.412 156.107 78.297  1.00 51.19  ? 315 ASP A CA  1 
ATOM   2086  C C   . ASP A 1 295 ? 110.154 155.350 78.718  1.00 51.02  ? 315 ASP A C   1 
ATOM   2087  O O   . ASP A 1 295 ? 110.095 154.127 78.639  1.00 49.52  ? 315 ASP A O   1 
ATOM   2088  C CB  . ASP A 1 295 ? 111.429 156.386 76.790  1.00 54.79  ? 315 ASP A CB  1 
ATOM   2089  C CG  . ASP A 1 295 ? 111.027 155.217 75.903  1.00 58.20  ? 315 ASP A CG  1 
ATOM   2090  O OD1 . ASP A 1 295 ? 111.058 154.069 76.386  1.00 58.58  ? 315 ASP A OD1 1 
ATOM   2091  O OD2 . ASP A 1 295 ? 110.674 155.472 74.734  1.00 60.01  ? 315 ASP A OD2 1 
ATOM   2092  N N   . GLY A 1 296 ? 109.153 156.086 79.207  1.00 52.53  ? 316 GLY A N   1 
ATOM   2093  C CA  . GLY A 1 296 ? 107.931 155.488 79.723  1.00 53.85  ? 316 GLY A CA  1 
ATOM   2094  C C   . GLY A 1 296 ? 108.077 155.010 81.169  1.00 53.68  ? 316 GLY A C   1 
ATOM   2095  O O   . GLY A 1 296 ? 107.123 155.081 81.941  1.00 54.54  ? 316 GLY A O   1 
ATOM   2096  N N   . TYR A 1 297 ? 109.264 154.505 81.526  1.00 53.03  ? 317 TYR A N   1 
ATOM   2097  C CA  . TYR A 1 297 ? 109.477 153.901 82.832  1.00 53.72  ? 317 TYR A CA  1 
ATOM   2098  C C   . TYR A 1 297 ? 110.520 154.702 83.606  1.00 53.97  ? 317 TYR A C   1 
ATOM   2099  O O   . TYR A 1 297 ? 111.420 154.128 84.211  1.00 53.64  ? 317 TYR A O   1 
ATOM   2100  C CB  . TYR A 1 297 ? 109.902 152.435 82.695  1.00 54.01  ? 317 TYR A CB  1 
ATOM   2101  C CG  . TYR A 1 297 ? 108.916 151.558 81.967  1.00 55.05  ? 317 TYR A CG  1 
ATOM   2102  C CD1 . TYR A 1 297 ? 108.664 151.748 80.618  1.00 56.07  ? 317 TYR A CD1 1 
ATOM   2103  C CD2 . TYR A 1 297 ? 108.199 150.574 82.630  1.00 55.88  ? 317 TYR A CD2 1 
ATOM   2104  C CE1 . TYR A 1 297 ? 107.754 150.955 79.935  1.00 56.87  ? 317 TYR A CE1 1 
ATOM   2105  C CE2 . TYR A 1 297 ? 107.285 149.774 81.963  1.00 56.86  ? 317 TYR A CE2 1 
ATOM   2106  C CZ  . TYR A 1 297 ? 107.055 149.970 80.611  1.00 57.52  ? 317 TYR A CZ  1 
ATOM   2107  O OH  . TYR A 1 297 ? 106.147 149.186 79.940  1.00 58.49  ? 317 TYR A OH  1 
ATOM   2108  N N   . GLN A 1 298 ? 110.392 156.033 83.585  1.00 54.49  ? 318 GLN A N   1 
ATOM   2109  C CA  . GLN A 1 298 ? 111.361 156.890 84.248  1.00 55.15  ? 318 GLN A CA  1 
ATOM   2110  C C   . GLN A 1 298 ? 111.236 156.772 85.765  1.00 57.19  ? 318 GLN A C   1 
ATOM   2111  O O   . GLN A 1 298 ? 112.243 156.783 86.470  1.00 57.59  ? 318 GLN A O   1 
ATOM   2112  C CB  . GLN A 1 298 ? 111.203 158.351 83.825  1.00 55.25  ? 318 GLN A CB  1 
ATOM   2113  C CG  . GLN A 1 298 ? 111.806 158.658 82.463  1.00 56.16  ? 318 GLN A CG  1 
ATOM   2114  C CD  . GLN A 1 298 ? 110.818 158.572 81.327  1.00 57.48  ? 318 GLN A CD  1 
ATOM   2115  O OE1 . GLN A 1 298 ? 109.929 157.726 81.317  1.00 57.03  ? 318 GLN A OE1 1 
ATOM   2116  N NE2 . GLN A 1 298 ? 110.961 159.466 80.363  1.00 58.76  ? 318 GLN A NE2 1 
ATOM   2117  N N   . ARG A 1 299 ? 109.997 156.654 86.255  1.00 59.24  ? 319 ARG A N   1 
ATOM   2118  C CA  . ARG A 1 299 ? 109.712 156.692 87.682  1.00 60.28  ? 319 ARG A CA  1 
ATOM   2119  C C   . ARG A 1 299 ? 110.420 155.563 88.430  1.00 57.19  ? 319 ARG A C   1 
ATOM   2120  O O   . ARG A 1 299 ? 110.639 155.667 89.634  1.00 56.65  ? 319 ARG A O   1 
ATOM   2121  C CB  . ARG A 1 299 ? 108.199 156.598 87.920  1.00 63.99  ? 319 ARG A CB  1 
ATOM   2122  C CG  . ARG A 1 299 ? 107.450 157.920 87.806  1.00 66.50  ? 319 ARG A CG  1 
ATOM   2123  C CD  . ARG A 1 299 ? 107.930 158.967 88.803  1.00 68.54  ? 319 ARG A CD  1 
ATOM   2124  N NE  . ARG A 1 299 ? 108.176 158.425 90.138  1.00 70.08  ? 319 ARG A NE  1 
ATOM   2125  C CZ  . ARG A 1 299 ? 109.266 158.649 90.871  1.00 71.57  ? 319 ARG A CZ  1 
ATOM   2126  N NH1 . ARG A 1 299 ? 110.190 159.501 90.460  1.00 71.23  ? 319 ARG A NH1 1 
ATOM   2127  N NH2 . ARG A 1 299 ? 109.414 158.037 92.034  1.00 72.20  ? 319 ARG A NH2 1 
ATOM   2128  N N   . GLU A 1 300 ? 110.768 154.489 87.715  1.00 54.80  ? 320 GLU A N   1 
ATOM   2129  C CA  . GLU A 1 300 ? 111.191 153.247 88.339  1.00 53.70  ? 320 GLU A CA  1 
ATOM   2130  C C   . GLU A 1 300 ? 112.702 153.067 88.250  1.00 50.22  ? 320 GLU A C   1 
ATOM   2131  O O   . GLU A 1 300 ? 113.245 152.164 88.883  1.00 49.60  ? 320 GLU A O   1 
ATOM   2132  C CB  . GLU A 1 300 ? 110.461 152.102 87.649  1.00 55.70  ? 320 GLU A CB  1 
ATOM   2133  C CG  . GLU A 1 300 ? 109.059 152.515 87.258  1.00 58.62  ? 320 GLU A CG  1 
ATOM   2134  C CD  . GLU A 1 300 ? 108.194 151.372 86.786  1.00 61.71  ? 320 GLU A CD  1 
ATOM   2135  O OE1 . GLU A 1 300 ? 108.690 150.237 86.799  1.00 63.00  ? 320 GLU A OE1 1 
ATOM   2136  O OE2 . GLU A 1 300 ? 107.041 151.627 86.401  1.00 62.19  ? 320 GLU A OE2 1 
ATOM   2137  N N   . ALA A 1 301 ? 113.378 153.908 87.455  1.00 46.01  ? 321 ALA A N   1 
ATOM   2138  C CA  . ALA A 1 301 ? 114.825 153.834 87.311  1.00 42.54  ? 321 ALA A CA  1 
ATOM   2139  C C   . ALA A 1 301 ? 115.498 155.044 87.955  1.00 41.22  ? 321 ALA A C   1 
ATOM   2140  O O   . ALA A 1 301 ? 116.708 155.205 87.827  1.00 40.99  ? 321 ALA A O   1 
ATOM   2141  C CB  . ALA A 1 301 ? 115.198 153.720 85.852  1.00 41.71  ? 321 ALA A CB  1 
ATOM   2142  N N   . VAL A 1 302 ? 114.721 155.891 88.643  1.00 40.43  ? 322 VAL A N   1 
ATOM   2143  C CA  . VAL A 1 302 ? 115.280 157.053 89.315  1.00 39.89  ? 322 VAL A CA  1 
ATOM   2144  C C   . VAL A 1 302 ? 116.296 156.581 90.349  1.00 38.88  ? 322 VAL A C   1 
ATOM   2145  O O   . VAL A 1 302 ? 116.047 155.633 91.092  1.00 38.33  ? 322 VAL A O   1 
ATOM   2146  C CB  . VAL A 1 302 ? 114.201 157.938 89.967  1.00 40.83  ? 322 VAL A CB  1 
ATOM   2147  C CG1 . VAL A 1 302 ? 113.282 158.545 88.930  1.00 41.43  ? 322 VAL A CG1 1 
ATOM   2148  C CG2 . VAL A 1 302 ? 113.399 157.202 91.032  1.00 41.60  ? 322 VAL A CG2 1 
ATOM   2149  N N   . GLY A 1 303 ? 117.456 157.250 90.361  1.00 38.47  ? 323 GLY A N   1 
ATOM   2150  C CA  . GLY A 1 303 ? 118.508 156.956 91.317  1.00 38.04  ? 323 GLY A CA  1 
ATOM   2151  C C   . GLY A 1 303 ? 119.537 155.963 90.782  1.00 36.85  ? 323 GLY A C   1 
ATOM   2152  O O   . GLY A 1 303 ? 120.606 155.824 91.370  1.00 37.33  ? 323 GLY A O   1 
ATOM   2153  N N   . GLY A 1 304 ? 119.215 155.283 89.671  1.00 35.03  ? 324 GLY A N   1 
ATOM   2154  C CA  . GLY A 1 304 ? 120.103 154.293 89.083  1.00 33.92  ? 324 GLY A CA  1 
ATOM   2155  C C   . GLY A 1 304 ? 121.420 154.914 88.626  1.00 32.36  ? 324 GLY A C   1 
ATOM   2156  O O   . GLY A 1 304 ? 121.427 156.009 88.074  1.00 32.19  ? 324 GLY A O   1 
ATOM   2157  N N   . ILE A 1 305 ? 122.526 154.207 88.878  1.00 31.04  ? 325 ILE A N   1 
ATOM   2158  C CA  . ILE A 1 305 ? 123.855 154.699 88.557  1.00 30.31  ? 325 ILE A CA  1 
ATOM   2159  C C   . ILE A 1 305 ? 124.426 153.824 87.448  1.00 29.76  ? 325 ILE A C   1 
ATOM   2160  O O   . ILE A 1 305 ? 124.440 152.601 87.573  1.00 30.52  ? 325 ILE A O   1 
ATOM   2161  C CB  . ILE A 1 305 ? 124.760 154.699 89.805  1.00 30.69  ? 325 ILE A CB  1 
ATOM   2162  C CG1 . ILE A 1 305 ? 124.137 155.481 90.963  1.00 31.26  ? 325 ILE A CG1 1 
ATOM   2163  C CG2 . ILE A 1 305 ? 126.147 155.218 89.464  1.00 30.63  ? 325 ILE A CG2 1 
ATOM   2164  C CD1 . ILE A 1 305 ? 124.846 155.272 92.283  1.00 31.56  ? 325 ILE A CD1 1 
ATOM   2165  N N   . THR A 1 306 ? 124.906 154.467 86.378  1.00 28.62  ? 326 THR A N   1 
ATOM   2166  C CA  . THR A 1 306 ? 125.364 153.761 85.195  1.00 27.64  ? 326 THR A CA  1 
ATOM   2167  C C   . THR A 1 306 ? 126.777 154.208 84.848  1.00 26.82  ? 326 THR A C   1 
ATOM   2168  O O   . THR A 1 306 ? 127.241 155.241 85.323  1.00 27.16  ? 326 THR A O   1 
ATOM   2169  C CB  . THR A 1 306 ? 124.434 154.008 84.003  1.00 27.79  ? 326 THR A CB  1 
ATOM   2170  O OG1 . THR A 1 306 ? 124.673 155.322 83.495  1.00 27.80  ? 326 THR A OG1 1 
ATOM   2171  C CG2 . THR A 1 306 ? 122.973 153.853 84.359  1.00 27.97  ? 326 THR A CG2 1 
ATOM   2172  N N   . ILE A 1 307 ? 127.431 153.416 83.996  1.00 26.15  ? 327 ILE A N   1 
ATOM   2173  C CA  . ILE A 1 307 ? 128.796 153.672 83.572  1.00 25.73  ? 327 ILE A CA  1 
ATOM   2174  C C   . ILE A 1 307 ? 128.808 153.803 82.055  1.00 26.07  ? 327 ILE A C   1 
ATOM   2175  O O   . ILE A 1 307 ? 128.484 152.853 81.349  1.00 26.72  ? 327 ILE A O   1 
ATOM   2176  C CB  . ILE A 1 307 ? 129.728 152.544 84.046  1.00 25.53  ? 327 ILE A CB  1 
ATOM   2177  C CG1 . ILE A 1 307 ? 129.549 152.269 85.539  1.00 25.58  ? 327 ILE A CG1 1 
ATOM   2178  C CG2 . ILE A 1 307 ? 131.165 152.857 83.679  1.00 25.85  ? 327 ILE A CG2 1 
ATOM   2179  C CD1 . ILE A 1 307 ? 130.602 151.385 86.134  1.00 25.71  ? 327 ILE A CD1 1 
ATOM   2180  N N   . LYS A 1 308 ? 129.196 154.982 81.571  1.00 26.74  ? 328 LYS A N   1 
ATOM   2181  C CA  . LYS A 1 308 ? 129.163 155.283 80.151  1.00 27.88  ? 328 LYS A CA  1 
ATOM   2182  C C   . LYS A 1 308 ? 130.579 155.557 79.665  1.00 30.05  ? 328 LYS A C   1 
ATOM   2183  O O   . LYS A 1 308 ? 131.273 156.390 80.238  1.00 31.08  ? 328 LYS A O   1 
ATOM   2184  C CB  . LYS A 1 308 ? 128.275 156.504 79.903  1.00 27.56  ? 328 LYS A CB  1 
ATOM   2185  C CG  . LYS A 1 308 ? 128.540 157.244 78.601  1.00 27.86  ? 328 LYS A CG  1 
ATOM   2186  C CD  . LYS A 1 308 ? 127.877 158.595 78.558  1.00 28.46  ? 328 LYS A CD  1 
ATOM   2187  C CE  . LYS A 1 308 ? 128.057 159.307 77.235  1.00 28.90  ? 328 LYS A CE  1 
ATOM   2188  N NZ  . LYS A 1 308 ? 129.483 159.581 76.946  1.00 28.99  ? 328 LYS A NZ  1 
ATOM   2189  N N   . LEU A 1 309 ? 130.986 154.880 78.589  1.00 32.33  ? 329 LEU A N   1 
ATOM   2190  C CA  . LEU A 1 309 ? 132.269 155.154 77.963  1.00 34.09  ? 329 LEU A CA  1 
ATOM   2191  C C   . LEU A 1 309 ? 132.288 156.587 77.442  1.00 36.81  ? 329 LEU A C   1 
ATOM   2192  O O   . LEU A 1 309 ? 131.366 157.003 76.741  1.00 37.80  ? 329 LEU A O   1 
ATOM   2193  C CB  . LEU A 1 309 ? 132.508 154.147 76.836  1.00 34.18  ? 329 LEU A CB  1 
ATOM   2194  C CG  . LEU A 1 309 ? 133.296 152.908 77.247  1.00 34.65  ? 329 LEU A CG  1 
ATOM   2195  C CD1 . LEU A 1 309 ? 133.324 151.882 76.131  1.00 34.38  ? 329 LEU A CD1 1 
ATOM   2196  C CD2 . LEU A 1 309 ? 134.716 153.289 77.630  1.00 35.42  ? 329 LEU A CD2 1 
ATOM   2197  N N   . GLN A 1 310 ? 133.344 157.330 77.799  1.00 40.18  ? 330 GLN A N   1 
ATOM   2198  C CA  . GLN A 1 310 ? 133.435 158.745 77.478  1.00 43.77  ? 330 GLN A CA  1 
ATOM   2199  C C   . GLN A 1 310 ? 133.613 158.922 75.973  1.00 46.66  ? 330 GLN A C   1 
ATOM   2200  O O   . GLN A 1 310 ? 134.554 158.392 75.384  1.00 47.73  ? 330 GLN A O   1 
ATOM   2201  C CB  . GLN A 1 310 ? 134.591 159.421 78.219  1.00 45.10  ? 330 GLN A CB  1 
ATOM   2202  C CG  . GLN A 1 310 ? 134.991 160.761 77.612  1.00 46.71  ? 330 GLN A CG  1 
ATOM   2203  C CD  . GLN A 1 310 ? 135.892 161.570 78.510  1.00 48.75  ? 330 GLN A CD  1 
ATOM   2204  O OE1 . GLN A 1 310 ? 137.106 161.620 78.318  1.00 49.52  ? 330 GLN A OE1 1 
ATOM   2205  N NE2 . GLN A 1 310 ? 135.303 162.200 79.514  1.00 49.58  ? 330 GLN A NE2 1 
ATOM   2206  N N   . SER A 1 311 ? 132.705 159.702 75.378  1.00 49.06  ? 331 SER A N   1 
ATOM   2207  C CA  . SER A 1 311 ? 132.750 160.022 73.964  1.00 51.62  ? 331 SER A CA  1 
ATOM   2208  C C   . SER A 1 311 ? 131.998 161.327 73.726  1.00 53.62  ? 331 SER A C   1 
ATOM   2209  O O   . SER A 1 311 ? 130.783 161.388 73.907  1.00 54.59  ? 331 SER A O   1 
ATOM   2210  C CB  . SER A 1 311 ? 132.179 158.900 73.142  1.00 52.01  ? 331 SER A CB  1 
ATOM   2211  O OG  . SER A 1 311 ? 132.242 159.203 71.756  1.00 52.59  ? 331 SER A OG  1 
ATOM   2212  N N   . PRO A 1 312 ? 132.682 162.412 73.306  1.00 56.76  ? 332 PRO A N   1 
ATOM   2213  C CA  . PRO A 1 312 ? 132.001 163.677 73.047  1.00 59.14  ? 332 PRO A CA  1 
ATOM   2214  C C   . PRO A 1 312 ? 131.156 163.564 71.783  1.00 60.78  ? 332 PRO A C   1 
ATOM   2215  O O   . PRO A 1 312 ? 131.466 162.766 70.898  1.00 60.70  ? 332 PRO A O   1 
ATOM   2216  C CB  . PRO A 1 312 ? 133.119 164.716 72.886  1.00 59.76  ? 332 PRO A CB  1 
ATOM   2217  C CG  . PRO A 1 312 ? 134.414 163.926 72.744  1.00 59.45  ? 332 PRO A CG  1 
ATOM   2218  C CD  . PRO A 1 312 ? 134.119 162.464 73.010  1.00 58.16  ? 332 PRO A CD  1 
ATOM   2219  N N   . ASP A 1 313 ? 130.097 164.377 71.710  1.00 62.31  ? 333 ASP A N   1 
ATOM   2220  C CA  . ASP A 1 313 ? 129.234 164.410 70.542  1.00 64.21  ? 333 ASP A CA  1 
ATOM   2221  C C   . ASP A 1 313 ? 130.033 164.863 69.323  1.00 62.73  ? 333 ASP A C   1 
ATOM   2222  O O   . ASP A 1 313 ? 130.790 165.827 69.389  1.00 63.97  ? 333 ASP A O   1 
ATOM   2223  C CB  . ASP A 1 313 ? 128.016 165.310 70.762  1.00 68.08  ? 333 ASP A CB  1 
ATOM   2224  C CG  . ASP A 1 313 ? 126.920 164.676 71.604  1.00 72.66  ? 333 ASP A CG  1 
ATOM   2225  O OD1 . ASP A 1 313 ? 127.123 163.540 72.089  1.00 73.83  ? 333 ASP A OD1 1 
ATOM   2226  O OD2 . ASP A 1 313 ? 125.863 165.319 71.760  1.00 75.21  ? 333 ASP A OD2 1 
ATOM   2227  N N   . VAL A 1 314 ? 129.842 164.147 68.212  1.00 61.39  ? 334 VAL A N   1 
ATOM   2228  C CA  . VAL A 1 314 ? 130.461 164.484 66.943  1.00 61.26  ? 334 VAL A CA  1 
ATOM   2229  C C   . VAL A 1 314 ? 129.552 165.479 66.230  1.00 64.02  ? 334 VAL A C   1 
ATOM   2230  O O   . VAL A 1 314 ? 128.454 165.120 65.808  1.00 64.96  ? 334 VAL A O   1 
ATOM   2231  C CB  . VAL A 1 314 ? 130.686 163.221 66.093  1.00 59.33  ? 334 VAL A CB  1 
ATOM   2232  C CG1 . VAL A 1 314 ? 131.406 163.534 64.790  1.00 59.50  ? 334 VAL A CG1 1 
ATOM   2233  C CG2 . VAL A 1 314 ? 131.426 162.152 66.878  1.00 58.49  ? 334 VAL A CG2 1 
ATOM   2234  N N   . LYS A 1 315 ? 130.024 166.722 66.092  1.00 66.09  ? 335 LYS A N   1 
ATOM   2235  C CA  . LYS A 1 315 ? 129.161 167.820 65.692  1.00 68.82  ? 335 LYS A CA  1 
ATOM   2236  C C   . LYS A 1 315 ? 128.806 167.721 64.210  1.00 66.61  ? 335 LYS A C   1 
ATOM   2237  O O   . LYS A 1 315 ? 127.651 167.945 63.844  1.00 67.37  ? 335 LYS A O   1 
ATOM   2238  C CB  . LYS A 1 315 ? 129.819 169.170 65.991  1.00 74.27  ? 335 LYS A CB  1 
ATOM   2239  C CG  . LYS A 1 315 ? 128.940 170.374 65.678  1.00 78.87  ? 335 LYS A CG  1 
ATOM   2240  C CD  . LYS A 1 315 ? 129.595 171.708 65.958  1.00 81.83  ? 335 LYS A CD  1 
ATOM   2241  C CE  . LYS A 1 315 ? 128.688 172.881 65.646  1.00 83.83  ? 335 LYS A CE  1 
ATOM   2242  N NZ  . LYS A 1 315 ? 128.308 172.928 64.212  1.00 83.85  ? 335 LYS A NZ  1 
ATOM   2243  N N   . TRP A 1 316 ? 129.797 167.407 63.363  1.00 64.26  ? 336 TRP A N   1 
ATOM   2244  C CA  . TRP A 1 316 ? 129.576 167.393 61.924  1.00 63.45  ? 336 TRP A CA  1 
ATOM   2245  C C   . TRP A 1 316 ? 128.588 166.290 61.547  1.00 59.96  ? 336 TRP A C   1 
ATOM   2246  O O   . TRP A 1 316 ? 127.853 166.432 60.571  1.00 59.88  ? 336 TRP A O   1 
ATOM   2247  C CB  . TRP A 1 316 ? 130.894 167.277 61.144  1.00 65.14  ? 336 TRP A CB  1 
ATOM   2248  C CG  . TRP A 1 316 ? 131.760 166.114 61.520  1.00 64.77  ? 336 TRP A CG  1 
ATOM   2249  C CD1 . TRP A 1 316 ? 132.852 166.150 62.335  1.00 64.69  ? 336 TRP A CD1 1 
ATOM   2250  C CD2 . TRP A 1 316 ? 131.646 164.755 61.061  1.00 64.70  ? 336 TRP A CD2 1 
ATOM   2251  N NE1 . TRP A 1 316 ? 133.412 164.905 62.436  1.00 64.27  ? 336 TRP A NE1 1 
ATOM   2252  C CE2 . TRP A 1 316 ? 132.692 164.029 61.669  1.00 64.37  ? 336 TRP A CE2 1 
ATOM   2253  C CE3 . TRP A 1 316 ? 130.766 164.076 60.206  1.00 65.76  ? 336 TRP A CE3 1 
ATOM   2254  C CZ2 . TRP A 1 316 ? 132.874 162.665 61.453  1.00 65.13  ? 336 TRP A CZ2 1 
ATOM   2255  C CZ3 . TRP A 1 316 ? 130.945 162.724 60.000  1.00 65.38  ? 336 TRP A CZ3 1 
ATOM   2256  C CH2 . TRP A 1 316 ? 131.983 162.028 60.620  1.00 65.08  ? 336 TRP A CH2 1 
ATOM   2257  N N   . PHE A 1 317 ? 128.568 165.203 62.328  1.00 56.73  ? 337 PHE A N   1 
ATOM   2258  C CA  . PHE A 1 317 ? 127.597 164.147 62.111  1.00 55.19  ? 337 PHE A CA  1 
ATOM   2259  C C   . PHE A 1 317 ? 126.184 164.686 62.315  1.00 56.23  ? 337 PHE A C   1 
ATOM   2260  O O   . PHE A 1 317 ? 125.293 164.382 61.528  1.00 56.31  ? 337 PHE A O   1 
ATOM   2261  C CB  . PHE A 1 317 ? 127.846 162.952 63.031  1.00 53.46  ? 337 PHE A CB  1 
ATOM   2262  C CG  . PHE A 1 317 ? 126.722 161.952 62.997  1.00 51.17  ? 337 PHE A CG  1 
ATOM   2263  C CD1 . PHE A 1 317 ? 126.424 161.272 61.828  1.00 49.43  ? 337 PHE A CD1 1 
ATOM   2264  C CD2 . PHE A 1 317 ? 125.918 161.750 64.106  1.00 50.45  ? 337 PHE A CD2 1 
ATOM   2265  C CE1 . PHE A 1 317 ? 125.370 160.376 61.781  1.00 48.93  ? 337 PHE A CE1 1 
ATOM   2266  C CE2 . PHE A 1 317 ? 124.869 160.846 64.060  1.00 50.02  ? 337 PHE A CE2 1 
ATOM   2267  C CZ  . PHE A 1 317 ? 124.596 160.165 62.897  1.00 49.33  ? 337 PHE A CZ  1 
ATOM   2268  N N   . ASP A 1 318 ? 125.983 165.478 63.375  1.00 57.66  ? 338 ASP A N   1 
ATOM   2269  C CA  . ASP A 1 318 ? 124.685 166.078 63.637  1.00 59.14  ? 338 ASP A CA  1 
ATOM   2270  C C   . ASP A 1 318 ? 124.304 167.009 62.491  1.00 60.54  ? 338 ASP A C   1 
ATOM   2271  O O   . ASP A 1 318 ? 123.169 166.970 62.023  1.00 61.56  ? 338 ASP A O   1 
ATOM   2272  C CB  . ASP A 1 318 ? 124.663 166.813 64.978  1.00 60.22  ? 338 ASP A CB  1 
ATOM   2273  C CG  . ASP A 1 318 ? 124.659 165.870 66.167  1.00 60.82  ? 338 ASP A CG  1 
ATOM   2274  O OD1 . ASP A 1 318 ? 124.148 164.739 66.012  1.00 60.47  ? 338 ASP A OD1 1 
ATOM   2275  O OD2 . ASP A 1 318 ? 125.188 166.256 67.227  1.00 61.42  ? 338 ASP A OD2 1 
ATOM   2276  N N   . ASP A 1 319 ? 125.257 167.829 62.037  1.00 63.30  ? 339 ASP A N   1 
ATOM   2277  C CA  . ASP A 1 319 ? 124.986 168.789 60.979  1.00 66.58  ? 339 ASP A CA  1 
ATOM   2278  C C   . ASP A 1 319 ? 124.532 168.065 59.713  1.00 64.75  ? 339 ASP A C   1 
ATOM   2279  O O   . ASP A 1 319 ? 123.622 168.531 59.031  1.00 64.68  ? 339 ASP A O   1 
ATOM   2280  C CB  . ASP A 1 319 ? 126.202 169.685 60.730  1.00 71.06  ? 339 ASP A CB  1 
ATOM   2281  C CG  . ASP A 1 319 ? 126.531 170.587 61.908  1.00 75.60  ? 339 ASP A CG  1 
ATOM   2282  O OD1 . ASP A 1 319 ? 125.787 170.536 62.913  1.00 76.93  ? 339 ASP A OD1 1 
ATOM   2283  O OD2 . ASP A 1 319 ? 127.529 171.330 61.816  1.00 78.46  ? 339 ASP A OD2 1 
ATOM   2284  N N   . TYR A 1 320 ? 125.156 166.920 59.413  1.00 63.13  ? 340 TYR A N   1 
ATOM   2285  C CA  . TYR A 1 320 ? 124.810 166.143 58.233  1.00 61.46  ? 340 TYR A CA  1 
ATOM   2286  C C   . TYR A 1 320 ? 123.464 165.448 58.425  1.00 59.56  ? 340 TYR A C   1 
ATOM   2287  O O   . TYR A 1 320 ? 122.656 165.403 57.499  1.00 60.31  ? 340 TYR A O   1 
ATOM   2288  C CB  . TYR A 1 320 ? 125.907 165.121 57.918  1.00 61.83  ? 340 TYR A CB  1 
ATOM   2289  C CG  . TYR A 1 320 ? 125.478 164.012 56.991  1.00 61.91  ? 340 TYR A CG  1 
ATOM   2290  C CD1 . TYR A 1 320 ? 125.182 164.267 55.662  1.00 62.79  ? 340 TYR A CD1 1 
ATOM   2291  C CD2 . TYR A 1 320 ? 125.344 162.709 57.447  1.00 61.13  ? 340 TYR A CD2 1 
ATOM   2292  C CE1 . TYR A 1 320 ? 124.788 163.253 54.803  1.00 63.34  ? 340 TYR A CE1 1 
ATOM   2293  C CE2 . TYR A 1 320 ? 124.950 161.685 56.603  1.00 61.05  ? 340 TYR A CE2 1 
ATOM   2294  C CZ  . TYR A 1 320 ? 124.671 161.958 55.276  1.00 62.59  ? 340 TYR A CZ  1 
ATOM   2295  O OH  . TYR A 1 320 ? 124.272 160.956 54.425  1.00 63.14  ? 340 TYR A OH  1 
ATOM   2296  N N   . TYR A 1 321 ? 123.237 164.904 59.627  1.00 57.64  ? 341 TYR A N   1 
ATOM   2297  C CA  . TYR A 1 321 ? 122.128 163.996 59.879  1.00 57.03  ? 341 TYR A CA  1 
ATOM   2298  C C   . TYR A 1 321 ? 120.806 164.759 59.927  1.00 58.03  ? 341 TYR A C   1 
ATOM   2299  O O   . TYR A 1 321 ? 119.814 164.313 59.360  1.00 58.01  ? 341 TYR A O   1 
ATOM   2300  C CB  . TYR A 1 321 ? 122.368 163.231 61.183  1.00 56.57  ? 341 TYR A CB  1 
ATOM   2301  C CG  . TYR A 1 321 ? 121.338 162.183 61.524  1.00 55.97  ? 341 TYR A CG  1 
ATOM   2302  C CD1 . TYR A 1 321 ? 121.207 161.030 60.765  1.00 55.99  ? 341 TYR A CD1 1 
ATOM   2303  C CD2 . TYR A 1 321 ? 120.503 162.334 62.620  1.00 55.50  ? 341 TYR A CD2 1 
ATOM   2304  C CE1 . TYR A 1 321 ? 120.267 160.062 61.078  1.00 55.63  ? 341 TYR A CE1 1 
ATOM   2305  C CE2 . TYR A 1 321 ? 119.559 161.376 62.947  1.00 55.45  ? 341 TYR A CE2 1 
ATOM   2306  C CZ  . TYR A 1 321 ? 119.441 160.235 62.175  1.00 55.70  ? 341 TYR A CZ  1 
ATOM   2307  O OH  . TYR A 1 321 ? 118.505 159.287 62.504  1.00 56.24  ? 341 TYR A OH  1 
ATOM   2308  N N   . LEU A 1 322 ? 120.795 165.918 60.593  1.00 59.34  ? 342 LEU A N   1 
ATOM   2309  C CA  . LEU A 1 322 ? 119.548 166.608 60.881  1.00 59.70  ? 342 LEU A CA  1 
ATOM   2310  C C   . LEU A 1 322 ? 118.935 167.198 59.611  1.00 63.09  ? 342 LEU A C   1 
ATOM   2311  O O   . LEU A 1 322 ? 117.764 167.566 59.618  1.00 64.47  ? 342 LEU A O   1 
ATOM   2312  C CB  . LEU A 1 322 ? 119.809 167.689 61.933  1.00 58.23  ? 342 LEU A CB  1 
ATOM   2313  C CG  . LEU A 1 322 ? 120.437 167.189 63.235  1.00 57.72  ? 342 LEU A CG  1 
ATOM   2314  C CD1 . LEU A 1 322 ? 120.578 168.320 64.239  1.00 59.35  ? 342 LEU A CD1 1 
ATOM   2315  C CD2 . LEU A 1 322 ? 119.647 166.041 63.841  1.00 56.52  ? 342 LEU A CD2 1 
ATOM   2316  N N   . LYS A 1 323 ? 119.704 167.263 58.514  1.00 66.06  ? 343 LYS A N   1 
ATOM   2317  C CA  . LYS A 1 323 ? 119.201 167.813 57.264  1.00 69.47  ? 343 LYS A CA  1 
ATOM   2318  C C   . LYS A 1 323 ? 118.718 166.712 56.320  1.00 69.59  ? 343 LYS A C   1 
ATOM   2319  O O   . LYS A 1 323 ? 118.323 167.007 55.194  1.00 69.36  ? 343 LYS A O   1 
ATOM   2320  C CB  . LYS A 1 323 ? 120.287 168.653 56.584  1.00 72.48  ? 343 LYS A CB  1 
ATOM   2321  C CG  . LYS A 1 323 ? 120.666 169.926 57.328  1.00 75.53  ? 343 LYS A CG  1 
ATOM   2322  C CD  . LYS A 1 323 ? 121.482 170.902 56.499  1.00 78.01  ? 343 LYS A CD  1 
ATOM   2323  C CE  . LYS A 1 323 ? 122.822 170.357 56.050  1.00 79.15  ? 343 LYS A CE  1 
ATOM   2324  N NZ  . LYS A 1 323 ? 123.741 170.139 57.192  1.00 79.89  ? 343 LYS A NZ  1 
ATOM   2325  N N   . LEU A 1 324 ? 118.738 165.450 56.769  1.00 70.10  ? 344 LEU A N   1 
ATOM   2326  C CA  . LEU A 1 324 ? 118.331 164.339 55.921  1.00 71.66  ? 344 LEU A CA  1 
ATOM   2327  C C   . LEU A 1 324 ? 116.816 164.345 55.735  1.00 74.47  ? 344 LEU A C   1 
ATOM   2328  O O   . LEU A 1 324 ? 116.062 164.553 56.684  1.00 75.06  ? 344 LEU A O   1 
ATOM   2329  C CB  . LEU A 1 324 ? 118.790 163.013 56.535  1.00 70.68  ? 344 LEU A CB  1 
ATOM   2330  C CG  . LEU A 1 324 ? 120.255 162.647 56.311  1.00 70.23  ? 344 LEU A CG  1 
ATOM   2331  C CD1 . LEU A 1 324 ? 120.570 161.293 56.926  1.00 69.51  ? 344 LEU A CD1 1 
ATOM   2332  C CD2 . LEU A 1 324 ? 120.591 162.631 54.827  1.00 70.40  ? 344 LEU A CD2 1 
ATOM   2333  N N   . ARG A 1 325 ? 116.397 164.094 54.490  1.00 77.21  ? 345 ARG A N   1 
ATOM   2334  C CA  . ARG A 1 325 ? 114.995 163.968 54.139  1.00 79.97  ? 345 ARG A CA  1 
ATOM   2335  C C   . ARG A 1 325 ? 114.774 162.627 53.452  1.00 80.90  ? 345 ARG A C   1 
ATOM   2336  O O   . ARG A 1 325 ? 115.654 162.136 52.746  1.00 81.32  ? 345 ARG A O   1 
ATOM   2337  C CB  . ARG A 1 325 ? 114.590 165.104 53.201  1.00 81.86  ? 345 ARG A CB  1 
ATOM   2338  C CG  . ARG A 1 325 ? 114.932 166.490 53.730  1.00 82.82  ? 345 ARG A CG  1 
ATOM   2339  C CD  . ARG A 1 325 ? 114.205 166.808 55.026  1.00 82.86  ? 345 ARG A CD  1 
ATOM   2340  N NE  . ARG A 1 325 ? 112.764 166.657 54.882  1.00 82.39  ? 345 ARG A NE  1 
ATOM   2341  C CZ  . ARG A 1 325 ? 111.873 166.906 55.836  1.00 83.11  ? 345 ARG A CZ  1 
ATOM   2342  N NH1 . ARG A 1 325 ? 112.260 167.348 57.021  1.00 83.20  ? 345 ARG A NH1 1 
ATOM   2343  N NH2 . ARG A 1 325 ? 110.586 166.730 55.590  1.00 84.17  ? 345 ARG A NH2 1 
ATOM   2344  N N   . PRO A 1 326 ? 113.594 161.993 53.631  1.00 83.40  ? 346 PRO A N   1 
ATOM   2345  C CA  . PRO A 1 326 ? 113.312 160.708 52.991  1.00 86.56  ? 346 PRO A CA  1 
ATOM   2346  C C   . PRO A 1 326 ? 113.265 160.758 51.464  1.00 92.69  ? 346 PRO A C   1 
ATOM   2347  O O   . PRO A 1 326 ? 113.481 159.734 50.819  1.00 93.98  ? 346 PRO A O   1 
ATOM   2348  C CB  . PRO A 1 326 ? 111.948 160.302 53.568  1.00 84.69  ? 346 PRO A CB  1 
ATOM   2349  C CG  . PRO A 1 326 ? 111.319 161.602 54.010  1.00 83.81  ? 346 PRO A CG  1 
ATOM   2350  C CD  . PRO A 1 326 ? 112.476 162.466 54.464  1.00 83.19  ? 346 PRO A CD  1 
ATOM   2351  N N   . GLU A 1 327 ? 113.014 161.944 50.888  1.00 99.73  ? 347 GLU A N   1 
ATOM   2352  C CA  . GLU A 1 327 ? 112.936 162.066 49.438  1.00 106.87 ? 347 GLU A CA  1 
ATOM   2353  C C   . GLU A 1 327 ? 114.334 162.016 48.820  1.00 107.94 ? 347 GLU A C   1 
ATOM   2354  O O   . GLU A 1 327 ? 114.523 161.369 47.790  1.00 107.65 ? 347 GLU A O   1 
ATOM   2355  C CB  . GLU A 1 327 ? 112.212 163.339 48.995  1.00 111.47 ? 347 GLU A CB  1 
ATOM   2356  C CG  . GLU A 1 327 ? 110.852 163.539 49.631  1.00 114.61 ? 347 GLU A CG  1 
ATOM   2357  C CD  . GLU A 1 327 ? 110.846 164.304 50.942  1.00 116.60 ? 347 GLU A CD  1 
ATOM   2358  O OE1 . GLU A 1 327 ? 111.918 164.775 51.368  1.00 115.87 ? 347 GLU A OE1 1 
ATOM   2359  O OE2 . GLU A 1 327 ? 109.761 164.436 51.528  1.00 118.19 ? 347 GLU A OE2 1 
ATOM   2360  N N   . THR A 1 328 ? 115.306 162.677 49.460  1.00 109.61 ? 348 THR A N   1 
ATOM   2361  C CA  . THR A 1 328 ? 116.617 162.887 48.863  1.00 112.41 ? 348 THR A CA  1 
ATOM   2362  C C   . THR A 1 328 ? 117.658 161.933 49.452  1.00 110.39 ? 348 THR A C   1 
ATOM   2363  O O   . THR A 1 328 ? 118.851 162.098 49.203  1.00 110.40 ? 348 THR A O   1 
ATOM   2364  C CB  . THR A 1 328 ? 117.057 164.351 49.005  1.00 116.47 ? 348 THR A CB  1 
ATOM   2365  O OG1 . THR A 1 328 ? 118.412 164.449 48.565  1.00 118.09 ? 348 THR A OG1 1 
ATOM   2366  C CG2 . THR A 1 328 ? 116.939 164.883 50.417  1.00 117.52 ? 348 THR A CG2 1 
ATOM   2367  N N   . ASN A 1 329 ? 117.206 160.931 50.214  1.00 106.80 ? 349 ASN A N   1 
ATOM   2368  C CA  . ASN A 1 329 ? 118.099 159.943 50.801  1.00 103.60 ? 349 ASN A CA  1 
ATOM   2369  C C   . ASN A 1 329 ? 117.677 158.552 50.337  1.00 102.39 ? 349 ASN A C   1 
ATOM   2370  O O   . ASN A 1 329 ? 116.811 157.928 50.948  1.00 101.12 ? 349 ASN A O   1 
ATOM   2371  C CB  . ASN A 1 329 ? 118.121 160.047 52.328  1.00 102.49 ? 349 ASN A CB  1 
ATOM   2372  C CG  . ASN A 1 329 ? 119.061 159.049 52.971  1.00 100.82 ? 349 ASN A CG  1 
ATOM   2373  O OD1 . ASN A 1 329 ? 118.732 157.871 53.112  1.00 99.16  ? 349 ASN A OD1 1 
ATOM   2374  N ND2 . ASN A 1 329 ? 120.231 159.521 53.373  1.00 100.39 ? 349 ASN A ND2 1 
ATOM   2375  N N   . LEU A 1 330 ? 118.306 158.077 49.254  1.00 103.52 ? 350 LEU A N   1 
ATOM   2376  C CA  . LEU A 1 330 ? 117.937 156.815 48.631  1.00 104.41 ? 350 LEU A CA  1 
ATOM   2377  C C   . LEU A 1 330 ? 118.966 155.725 48.934  1.00 98.73  ? 350 LEU A C   1 
ATOM   2378  O O   . LEU A 1 330 ? 118.633 154.544 48.883  1.00 96.86  ? 350 LEU A O   1 
ATOM   2379  C CB  . LEU A 1 330 ? 117.796 157.034 47.121  1.00 108.07 ? 350 LEU A CB  1 
ATOM   2380  C CG  . LEU A 1 330 ? 117.309 155.831 46.313  1.00 111.54 ? 350 LEU A CG  1 
ATOM   2381  C CD1 . LEU A 1 330 ? 115.997 155.285 46.861  1.00 111.59 ? 350 LEU A CD1 1 
ATOM   2382  C CD2 . LEU A 1 330 ? 117.157 156.208 44.852  1.00 112.94 ? 350 LEU A CD2 1 
ATOM   2383  N N   . ARG A 1 331 ? 120.211 156.118 49.241  1.00 93.83  ? 351 ARG A N   1 
ATOM   2384  C CA  . ARG A 1 331 ? 121.309 155.171 49.389  1.00 90.24  ? 351 ARG A CA  1 
ATOM   2385  C C   . ARG A 1 331 ? 121.175 154.363 50.681  1.00 83.11  ? 351 ARG A C   1 
ATOM   2386  O O   . ARG A 1 331 ? 121.838 153.337 50.838  1.00 82.44  ? 351 ARG A O   1 
ATOM   2387  C CB  . ARG A 1 331 ? 122.661 155.891 49.330  1.00 93.35  ? 351 ARG A CB  1 
ATOM   2388  C CG  . ARG A 1 331 ? 122.863 156.968 50.386  1.00 96.17  ? 351 ARG A CG  1 
ATOM   2389  C CD  . ARG A 1 331 ? 124.285 157.484 50.374  1.00 99.16  ? 351 ARG A CD  1 
ATOM   2390  N NE  . ARG A 1 331 ? 124.415 158.735 51.109  1.00 102.57 ? 351 ARG A NE  1 
ATOM   2391  C CZ  . ARG A 1 331 ? 125.558 159.385 51.298  1.00 105.32 ? 351 ARG A CZ  1 
ATOM   2392  N NH1 . ARG A 1 331 ? 126.704 158.860 50.899  1.00 105.18 ? 351 ARG A NH1 1 
ATOM   2393  N NH2 . ARG A 1 331 ? 125.551 160.554 51.919  1.00 105.87 ? 351 ARG A NH2 1 
ATOM   2394  N N   . ASN A 1 332 ? 120.323 154.827 51.605  1.00 75.76  ? 352 ASN A N   1 
ATOM   2395  C CA  . ASN A 1 332 ? 120.021 154.088 52.820  1.00 70.11  ? 352 ASN A CA  1 
ATOM   2396  C C   . ASN A 1 332 ? 118.697 153.355 52.621  1.00 68.18  ? 352 ASN A C   1 
ATOM   2397  O O   . ASN A 1 332 ? 117.647 153.987 52.534  1.00 68.91  ? 352 ASN A O   1 
ATOM   2398  C CB  . ASN A 1 332 ? 119.991 155.014 54.037  1.00 68.10  ? 352 ASN A CB  1 
ATOM   2399  C CG  . ASN A 1 332 ? 119.896 154.279 55.360  1.00 67.24  ? 352 ASN A CG  1 
ATOM   2400  O OD1 . ASN A 1 332 ? 119.472 153.126 55.419  1.00 67.00  ? 352 ASN A OD1 1 
ATOM   2401  N ND2 . ASN A 1 332 ? 120.279 154.944 56.437  1.00 66.57  ? 352 ASN A ND2 1 
ATOM   2402  N N   . PRO A 1 333 ? 118.691 152.006 52.531  1.00 65.53  ? 353 PRO A N   1 
ATOM   2403  C CA  . PRO A 1 333 ? 117.453 151.276 52.263  1.00 64.40  ? 353 PRO A CA  1 
ATOM   2404  C C   . PRO A 1 333 ? 116.481 151.239 53.443  1.00 62.41  ? 353 PRO A C   1 
ATOM   2405  O O   . PRO A 1 333 ? 115.302 150.953 53.251  1.00 63.36  ? 353 PRO A O   1 
ATOM   2406  C CB  . PRO A 1 333 ? 117.949 149.868 51.906  1.00 64.82  ? 353 PRO A CB  1 
ATOM   2407  C CG  . PRO A 1 333 ? 119.247 149.726 52.665  1.00 64.62  ? 353 PRO A CG  1 
ATOM   2408  C CD  . PRO A 1 333 ? 119.853 151.115 52.686  1.00 65.00  ? 353 PRO A CD  1 
ATOM   2409  N N   . TRP A 1 334 ? 116.969 151.545 54.652  1.00 59.52  ? 354 TRP A N   1 
ATOM   2410  C CA  . TRP A 1 334 ? 116.136 151.509 55.844  1.00 57.83  ? 354 TRP A CA  1 
ATOM   2411  C C   . TRP A 1 334 ? 115.658 152.897 56.259  1.00 58.05  ? 354 TRP A C   1 
ATOM   2412  O O   . TRP A 1 334 ? 115.021 153.022 57.302  1.00 58.71  ? 354 TRP A O   1 
ATOM   2413  C CB  . TRP A 1 334 ? 116.900 150.878 57.006  1.00 56.80  ? 354 TRP A CB  1 
ATOM   2414  C CG  . TRP A 1 334 ? 117.427 149.511 56.726  1.00 56.02  ? 354 TRP A CG  1 
ATOM   2415  C CD1 . TRP A 1 334 ? 116.734 148.336 56.737  1.00 56.53  ? 354 TRP A CD1 1 
ATOM   2416  C CD2 . TRP A 1 334 ? 118.786 149.182 56.404  1.00 55.21  ? 354 TRP A CD2 1 
ATOM   2417  N NE1 . TRP A 1 334 ? 117.575 147.292 56.461  1.00 56.46  ? 354 TRP A NE1 1 
ATOM   2418  C CE2 . TRP A 1 334 ? 118.838 147.782 56.248  1.00 55.70  ? 354 TRP A CE2 1 
ATOM   2419  C CE3 . TRP A 1 334 ? 119.958 149.930 56.255  1.00 55.40  ? 354 TRP A CE3 1 
ATOM   2420  C CZ2 . TRP A 1 334 ? 120.020 147.119 55.924  1.00 55.55  ? 354 TRP A CZ2 1 
ATOM   2421  C CZ3 . TRP A 1 334 ? 121.127 149.271 55.940  1.00 55.28  ? 354 TRP A CZ3 1 
ATOM   2422  C CH2 . TRP A 1 334 ? 121.153 147.885 55.773  1.00 55.18  ? 354 TRP A CH2 1 
ATOM   2423  N N   . PHE A 1 335 ? 115.970 153.937 55.480  1.00 58.42  ? 355 PHE A N   1 
ATOM   2424  C CA  . PHE A 1 335 ? 115.712 155.293 55.937  1.00 59.37  ? 355 PHE A CA  1 
ATOM   2425  C C   . PHE A 1 335 ? 114.215 155.599 55.918  1.00 62.45  ? 355 PHE A C   1 
ATOM   2426  O O   . PHE A 1 335 ? 113.721 156.301 56.797  1.00 63.68  ? 355 PHE A O   1 
ATOM   2427  C CB  . PHE A 1 335 ? 116.486 156.319 55.110  1.00 58.68  ? 355 PHE A CB  1 
ATOM   2428  C CG  . PHE A 1 335 ? 116.453 157.700 55.710  1.00 58.23  ? 355 PHE A CG  1 
ATOM   2429  C CD1 . PHE A 1 335 ? 117.058 157.948 56.933  1.00 58.08  ? 355 PHE A CD1 1 
ATOM   2430  C CD2 . PHE A 1 335 ? 115.783 158.737 55.081  1.00 59.19  ? 355 PHE A CD2 1 
ATOM   2431  C CE1 . PHE A 1 335 ? 117.020 159.211 57.500  1.00 58.99  ? 355 PHE A CE1 1 
ATOM   2432  C CE2 . PHE A 1 335 ? 115.749 160.003 55.648  1.00 59.91  ? 355 PHE A CE2 1 
ATOM   2433  C CZ  . PHE A 1 335 ? 116.370 160.237 56.854  1.00 60.10  ? 355 PHE A CZ  1 
ATOM   2434  N N   . GLN A 1 336 ? 113.496 155.064 54.926  1.00 63.66  ? 356 GLN A N   1 
ATOM   2435  C CA  . GLN A 1 336 ? 112.072 155.328 54.783  1.00 64.26  ? 356 GLN A CA  1 
ATOM   2436  C C   . GLN A 1 336 ? 111.302 154.626 55.901  1.00 61.04  ? 356 GLN A C   1 
ATOM   2437  O O   . GLN A 1 336 ? 110.379 155.200 56.480  1.00 62.24  ? 356 GLN A O   1 
ATOM   2438  C CB  . GLN A 1 336 ? 111.582 154.881 53.405  1.00 68.12  ? 356 GLN A CB  1 
ATOM   2439  C CG  . GLN A 1 336 ? 112.369 155.488 52.248  1.00 72.43  ? 356 GLN A CG  1 
ATOM   2440  C CD  . GLN A 1 336 ? 111.983 154.882 50.922  1.00 77.92  ? 356 GLN A CD  1 
ATOM   2441  O OE1 . GLN A 1 336 ? 110.856 154.434 50.735  1.00 81.85  ? 356 GLN A OE1 1 
ATOM   2442  N NE2 . GLN A 1 336 ? 112.921 154.861 49.986  1.00 79.81  ? 356 GLN A NE2 1 
ATOM   2443  N N   . GLU A 1 337 ? 111.681 153.377 56.194  1.00 58.53  ? 357 GLU A N   1 
ATOM   2444  C CA  . GLU A 1 337 ? 111.075 152.627 57.283  1.00 58.03  ? 357 GLU A CA  1 
ATOM   2445  C C   . GLU A 1 337 ? 111.310 153.365 58.600  1.00 55.72  ? 357 GLU A C   1 
ATOM   2446  O O   . GLU A 1 337 ? 110.420 153.431 59.445  1.00 56.39  ? 357 GLU A O   1 
ATOM   2447  C CB  . GLU A 1 337 ? 111.644 151.208 57.343  1.00 59.91  ? 357 GLU A CB  1 
ATOM   2448  C CG  . GLU A 1 337 ? 111.095 150.384 58.497  1.00 61.67  ? 357 GLU A CG  1 
ATOM   2449  C CD  . GLU A 1 337 ? 111.666 148.983 58.628  1.00 63.20  ? 357 GLU A CD  1 
ATOM   2450  O OE1 . GLU A 1 337 ? 112.407 148.554 57.719  1.00 63.57  ? 357 GLU A OE1 1 
ATOM   2451  O OE2 . GLU A 1 337 ? 111.377 148.329 59.652  1.00 63.56  ? 357 GLU A OE2 1 
ATOM   2452  N N   . PHE A 1 338 ? 112.522 153.907 58.765  1.00 53.20  ? 358 PHE A N   1 
ATOM   2453  C CA  . PHE A 1 338 ? 112.869 154.670 59.952  1.00 51.21  ? 358 PHE A CA  1 
ATOM   2454  C C   . PHE A 1 338 ? 112.014 155.929 60.040  1.00 51.92  ? 358 PHE A C   1 
ATOM   2455  O O   . PHE A 1 338 ? 111.574 156.297 61.125  1.00 52.09  ? 358 PHE A O   1 
ATOM   2456  C CB  . PHE A 1 338 ? 114.353 155.032 59.948  1.00 49.12  ? 358 PHE A CB  1 
ATOM   2457  C CG  . PHE A 1 338 ? 114.708 156.206 60.824  1.00 47.04  ? 358 PHE A CG  1 
ATOM   2458  C CD1 . PHE A 1 338 ? 114.631 156.111 62.204  1.00 46.17  ? 358 PHE A CD1 1 
ATOM   2459  C CD2 . PHE A 1 338 ? 115.090 157.415 60.263  1.00 46.45  ? 358 PHE A CD2 1 
ATOM   2460  C CE1 . PHE A 1 338 ? 114.956 157.194 63.007  1.00 46.31  ? 358 PHE A CE1 1 
ATOM   2461  C CE2 . PHE A 1 338 ? 115.411 158.497 61.066  1.00 46.37  ? 358 PHE A CE2 1 
ATOM   2462  C CZ  . PHE A 1 338 ? 115.339 158.387 62.436  1.00 46.46  ? 358 PHE A CZ  1 
ATOM   2463  N N   . TRP A 1 339 ? 111.797 156.586 58.896  1.00 53.26  ? 359 TRP A N   1 
ATOM   2464  C CA  . TRP A 1 339 ? 111.005 157.803 58.848  1.00 55.31  ? 359 TRP A CA  1 
ATOM   2465  C C   . TRP A 1 339 ? 109.579 157.517 59.310  1.00 57.42  ? 359 TRP A C   1 
ATOM   2466  O O   . TRP A 1 339 ? 109.010 158.300 60.065  1.00 59.63  ? 359 TRP A O   1 
ATOM   2467  C CB  . TRP A 1 339 ? 111.022 158.412 57.442  1.00 56.11  ? 359 TRP A CB  1 
ATOM   2468  C CG  . TRP A 1 339 ? 110.625 159.855 57.414  1.00 57.88  ? 359 TRP A CG  1 
ATOM   2469  C CD1 . TRP A 1 339 ? 109.392 160.366 57.128  1.00 59.37  ? 359 TRP A CD1 1 
ATOM   2470  C CD2 . TRP A 1 339 ? 111.482 160.984 57.652  1.00 58.89  ? 359 TRP A CD2 1 
ATOM   2471  N NE1 . TRP A 1 339 ? 109.419 161.734 57.195  1.00 59.65  ? 359 TRP A NE1 1 
ATOM   2472  C CE2 . TRP A 1 339 ? 110.687 162.141 57.515  1.00 59.56  ? 359 TRP A CE2 1 
ATOM   2473  C CE3 . TRP A 1 339 ? 112.835 161.131 57.978  1.00 59.71  ? 359 TRP A CE3 1 
ATOM   2474  C CZ2 . TRP A 1 339 ? 111.207 163.422 57.690  1.00 60.56  ? 359 TRP A CZ2 1 
ATOM   2475  C CZ3 . TRP A 1 339 ? 113.347 162.398 58.150  1.00 59.63  ? 359 TRP A CZ3 1 
ATOM   2476  C CH2 . TRP A 1 339 ? 112.542 163.528 58.009  1.00 60.15  ? 359 TRP A CH2 1 
ATOM   2477  N N   . GLN A 1 340 ? 109.007 156.398 58.849  1.00 58.48  ? 360 GLN A N   1 
ATOM   2478  C CA  . GLN A 1 340 ? 107.659 156.024 59.247  1.00 59.85  ? 360 GLN A CA  1 
ATOM   2479  C C   . GLN A 1 340 ? 107.612 155.683 60.736  1.00 60.73  ? 360 GLN A C   1 
ATOM   2480  O O   . GLN A 1 340 ? 106.696 156.107 61.434  1.00 62.55  ? 360 GLN A O   1 
ATOM   2481  C CB  . GLN A 1 340 ? 107.129 154.844 58.431  1.00 62.05  ? 360 GLN A CB  1 
ATOM   2482  C CG  . GLN A 1 340 ? 106.448 155.239 57.127  1.00 63.79  ? 360 GLN A CG  1 
ATOM   2483  C CD  . GLN A 1 340 ? 107.403 155.239 55.962  1.00 65.22  ? 360 GLN A CD  1 
ATOM   2484  O OE1 . GLN A 1 340 ? 107.601 156.250 55.296  1.00 66.24  ? 360 GLN A OE1 1 
ATOM   2485  N NE2 . GLN A 1 340 ? 107.997 154.086 55.697  1.00 66.03  ? 360 GLN A NE2 1 
ATOM   2486  N N   . HIS A 1 341 ? 108.589 154.908 61.216  1.00 62.07  ? 361 HIS A N   1 
ATOM   2487  C CA  . HIS A 1 341 ? 108.559 154.436 62.591  1.00 63.75  ? 361 HIS A CA  1 
ATOM   2488  C C   . HIS A 1 341 ? 108.729 155.604 63.559  1.00 64.61  ? 361 HIS A C   1 
ATOM   2489  O O   . HIS A 1 341 ? 108.041 155.667 64.575  1.00 65.38  ? 361 HIS A O   1 
ATOM   2490  C CB  . HIS A 1 341 ? 109.624 153.365 62.840  1.00 65.07  ? 361 HIS A CB  1 
ATOM   2491  C CG  . HIS A 1 341 ? 109.679 152.926 64.265  1.00 66.73  ? 361 HIS A CG  1 
ATOM   2492  N ND1 . HIS A 1 341 ? 108.672 152.207 64.870  1.00 68.17  ? 361 HIS A ND1 1 
ATOM   2493  C CD2 . HIS A 1 341 ? 110.612 153.115 65.204  1.00 68.52  ? 361 HIS A CD2 1 
ATOM   2494  C CE1 . HIS A 1 341 ? 108.999 151.970 66.131  1.00 69.64  ? 361 HIS A CE1 1 
ATOM   2495  N NE2 . HIS A 1 341 ? 110.172 152.517 66.356  1.00 69.67  ? 361 HIS A NE2 1 
ATOM   2496  N N   . ARG A 1 342 ? 109.653 156.518 63.234  1.00 65.72  ? 362 ARG A N   1 
ATOM   2497  C CA  . ARG A 1 342 ? 109.976 157.642 64.101  1.00 67.08  ? 362 ARG A CA  1 
ATOM   2498  C C   . ARG A 1 342 ? 108.766 158.566 64.203  1.00 68.31  ? 362 ARG A C   1 
ATOM   2499  O O   . ARG A 1 342 ? 108.182 158.714 65.272  1.00 67.85  ? 362 ARG A O   1 
ATOM   2500  C CB  . ARG A 1 342 ? 111.214 158.370 63.565  1.00 66.83  ? 362 ARG A CB  1 
ATOM   2501  C CG  . ARG A 1 342 ? 111.529 159.697 64.237  1.00 67.64  ? 362 ARG A CG  1 
ATOM   2502  C CD  . ARG A 1 342 ? 112.139 159.527 65.613  1.00 68.56  ? 362 ARG A CD  1 
ATOM   2503  N NE  . ARG A 1 342 ? 112.384 160.809 66.257  1.00 70.59  ? 362 ARG A NE  1 
ATOM   2504  C CZ  . ARG A 1 342 ? 113.304 161.696 65.883  1.00 72.48  ? 362 ARG A CZ  1 
ATOM   2505  N NH1 . ARG A 1 342 ? 114.128 161.437 64.883  1.00 72.38  ? 362 ARG A NH1 1 
ATOM   2506  N NH2 . ARG A 1 342 ? 113.417 162.841 66.535  1.00 73.90  ? 362 ARG A NH2 1 
ATOM   2507  N N   . PHE A 1 343 ? 108.417 159.202 63.082  1.00 71.27  ? 363 PHE A N   1 
ATOM   2508  C CA  . PHE A 1 343 ? 107.213 160.005 62.991  1.00 75.72  ? 363 PHE A CA  1 
ATOM   2509  C C   . PHE A 1 343 ? 106.101 159.101 62.479  1.00 80.87  ? 363 PHE A C   1 
ATOM   2510  O O   . PHE A 1 343 ? 106.092 158.761 61.302  1.00 83.48  ? 363 PHE A O   1 
ATOM   2511  C CB  . PHE A 1 343 ? 107.431 161.196 62.054  1.00 76.14  ? 363 PHE A CB  1 
ATOM   2512  C CG  . PHE A 1 343 ? 108.747 161.907 62.240  1.00 77.66  ? 363 PHE A CG  1 
ATOM   2513  C CD1 . PHE A 1 343 ? 109.056 162.522 63.444  1.00 78.83  ? 363 PHE A CD1 1 
ATOM   2514  C CD2 . PHE A 1 343 ? 109.683 161.944 61.217  1.00 77.75  ? 363 PHE A CD2 1 
ATOM   2515  C CE1 . PHE A 1 343 ? 110.274 163.162 63.621  1.00 78.95  ? 363 PHE A CE1 1 
ATOM   2516  C CE2 . PHE A 1 343 ? 110.897 162.589 61.391  1.00 78.36  ? 363 PHE A CE2 1 
ATOM   2517  C CZ  . PHE A 1 343 ? 111.190 163.195 62.594  1.00 79.16  ? 363 PHE A CZ  1 
ATOM   2518  N N   . GLN A 1 344 ? 105.191 158.694 63.371  1.00 84.23  ? 364 GLN A N   1 
ATOM   2519  C CA  . GLN A 1 344 ? 104.149 157.738 63.021  1.00 86.65  ? 364 GLN A CA  1 
ATOM   2520  C C   . GLN A 1 344 ? 103.343 158.297 61.849  1.00 90.39  ? 364 GLN A C   1 
ATOM   2521  O O   . GLN A 1 344 ? 102.556 159.223 62.032  1.00 92.75  ? 364 GLN A O   1 
ATOM   2522  C CB  . GLN A 1 344 ? 103.220 157.460 64.207  1.00 87.23  ? 364 GLN A CB  1 
ATOM   2523  C CG  . GLN A 1 344 ? 103.926 157.151 65.523  1.00 88.46  ? 364 GLN A CG  1 
ATOM   2524  C CD  . GLN A 1 344 ? 104.680 155.843 65.531  1.00 90.01  ? 364 GLN A CD  1 
ATOM   2525  O OE1 . GLN A 1 344 ? 104.574 155.033 64.615  1.00 90.42  ? 364 GLN A OE1 1 
ATOM   2526  N NE2 . GLN A 1 344 ? 105.438 155.617 66.592  1.00 91.37  ? 364 GLN A NE2 1 
ATOM   2527  N N   . CYS A 1 345 ? 103.562 157.750 60.646  1.00 94.62  ? 365 CYS A N   1 
ATOM   2528  C CA  . CYS A 1 345 ? 102.973 158.309 59.441  1.00 100.89 ? 365 CYS A CA  1 
ATOM   2529  C C   . CYS A 1 345 ? 103.117 157.328 58.282  1.00 102.92 ? 365 CYS A C   1 
ATOM   2530  O O   . CYS A 1 345 ? 103.675 156.246 58.442  1.00 102.03 ? 365 CYS A O   1 
ATOM   2531  C CB  . CYS A 1 345 ? 103.625 159.644 59.084  1.00 106.67 ? 365 CYS A CB  1 
ATOM   2532  S SG  . CYS A 1 345 ? 105.129 159.520 58.072  1.00 116.88 ? 365 CYS A SG  1 
ATOM   2533  N N   . ARG A 1 346 ? 102.610 157.745 57.116  1.00 109.72 ? 366 ARG A N   1 
ATOM   2534  C CA  . ARG A 1 346 ? 102.779 156.994 55.888  1.00 117.43 ? 366 ARG A CA  1 
ATOM   2535  C C   . ARG A 1 346 ? 103.231 157.939 54.781  1.00 119.79 ? 366 ARG A C   1 
ATOM   2536  O O   . ARG A 1 346 ? 102.630 158.993 54.586  1.00 122.33 ? 366 ARG A O   1 
ATOM   2537  C CB  . ARG A 1 346 ? 101.463 156.315 55.505  1.00 123.90 ? 366 ARG A CB  1 
ATOM   2538  C CG  . ARG A 1 346 ? 101.430 155.775 54.080  1.00 129.12 ? 366 ARG A CG  1 
ATOM   2539  C CD  . ARG A 1 346 ? 100.032 155.645 53.496  1.00 132.79 ? 366 ARG A CD  1 
ATOM   2540  N NE  . ARG A 1 346 ? 99.053  155.077 54.417  1.00 137.26 ? 366 ARG A NE  1 
ATOM   2541  C CZ  . ARG A 1 346 ? 97.882  154.553 54.063  1.00 140.94 ? 366 ARG A CZ  1 
ATOM   2542  N NH1 . ARG A 1 346 ? 97.557  154.429 52.787  1.00 141.69 ? 366 ARG A NH1 1 
ATOM   2543  N NH2 . ARG A 1 346 ? 97.042  154.128 54.992  1.00 140.64 ? 366 ARG A NH2 1 
ATOM   2544  N N   . LEU A 1 347 ? 104.276 157.535 54.049  1.00 123.95 ? 367 LEU A N   1 
ATOM   2545  C CA  . LEU A 1 347 ? 104.688 158.256 52.854  1.00 131.47 ? 367 LEU A CA  1 
ATOM   2546  C C   . LEU A 1 347 ? 104.103 157.546 51.637  1.00 142.92 ? 367 LEU A C   1 
ATOM   2547  O O   . LEU A 1 347 ? 104.551 156.460 51.279  1.00 145.74 ? 367 LEU A O   1 
ATOM   2548  C CB  . LEU A 1 347 ? 106.217 158.317 52.791  1.00 131.20 ? 367 LEU A CB  1 
ATOM   2549  C CG  . LEU A 1 347 ? 106.884 159.257 53.796  1.00 131.53 ? 367 LEU A CG  1 
ATOM   2550  C CD1 . LEU A 1 347 ? 108.353 158.907 53.955  1.00 129.79 ? 367 LEU A CD1 1 
ATOM   2551  C CD2 . LEU A 1 347 ? 106.744 160.715 53.368  1.00 133.12 ? 367 LEU A CD2 1 
ATOM   2552  N N   . GLU A 1 348 ? 103.097 158.170 51.019  1.00 155.39 ? 368 GLU A N   1 
ATOM   2553  C CA  . GLU A 1 348 ? 102.359 157.570 49.919  1.00 166.69 ? 368 GLU A CA  1 
ATOM   2554  C C   . GLU A 1 348 ? 103.194 157.576 48.640  1.00 170.87 ? 368 GLU A C   1 
ATOM   2555  O O   . GLU A 1 348 ? 102.943 156.773 47.747  1.00 170.02 ? 368 GLU A O   1 
ATOM   2556  C CB  . GLU A 1 348 ? 101.025 158.289 49.691  1.00 173.08 ? 368 GLU A CB  1 
ATOM   2557  C CG  . GLU A 1 348 ? 101.138 159.677 49.076  1.00 178.18 ? 368 GLU A CG  1 
ATOM   2558  C CD  . GLU A 1 348 ? 101.673 160.769 49.989  1.00 182.35 ? 368 GLU A CD  1 
ATOM   2559  O OE1 . GLU A 1 348 ? 101.938 160.478 51.176  1.00 183.42 ? 368 GLU A OE1 1 
ATOM   2560  O OE2 . GLU A 1 348 ? 101.827 161.909 49.510  1.00 183.72 ? 368 GLU A OE2 1 
ATOM   2561  N N   . GLY A 1 349 ? 104.184 158.475 48.553  1.00 177.04 ? 369 GLY A N   1 
ATOM   2562  C CA  . GLY A 1 349 ? 104.981 158.633 47.346  1.00 183.74 ? 369 GLY A CA  1 
ATOM   2563  C C   . GLY A 1 349 ? 106.176 157.680 47.272  1.00 189.93 ? 369 GLY A C   1 
ATOM   2564  O O   . GLY A 1 349 ? 107.043 157.855 46.418  1.00 190.34 ? 369 GLY A O   1 
ATOM   2565  N N   . PHE A 1 350 ? 106.222 156.678 48.162  1.00 194.96 ? 370 PHE A N   1 
ATOM   2566  C CA  . PHE A 1 350 ? 107.319 155.722 48.186  1.00 199.10 ? 370 PHE A CA  1 
ATOM   2567  C C   . PHE A 1 350 ? 106.772 154.296 48.167  1.00 201.52 ? 370 PHE A C   1 
ATOM   2568  O O   . PHE A 1 350 ? 105.653 154.060 48.615  1.00 199.45 ? 370 PHE A O   1 
ATOM   2569  C CB  . PHE A 1 350 ? 108.201 155.950 49.415  1.00 200.18 ? 370 PHE A CB  1 
ATOM   2570  C CG  . PHE A 1 350 ? 108.907 157.283 49.442  1.00 201.61 ? 370 PHE A CG  1 
ATOM   2571  C CD1 . PHE A 1 350 ? 108.230 158.436 49.809  1.00 200.46 ? 370 PHE A CD1 1 
ATOM   2572  C CD2 . PHE A 1 350 ? 110.236 157.395 49.067  1.00 201.95 ? 370 PHE A CD2 1 
ATOM   2573  C CE1 . PHE A 1 350 ? 108.873 159.664 49.830  1.00 199.70 ? 370 PHE A CE1 1 
ATOM   2574  C CE2 . PHE A 1 350 ? 110.882 158.622 49.092  1.00 201.22 ? 370 PHE A CE2 1 
ATOM   2575  C CZ  . PHE A 1 350 ? 110.197 159.756 49.467  1.00 199.19 ? 370 PHE A CZ  1 
ATOM   2576  N N   . PRO A 1 351 ? 107.530 153.308 47.635  1.00 205.21 ? 371 PRO A N   1 
ATOM   2577  C CA  . PRO A 1 351 ? 107.035 151.932 47.526  1.00 206.09 ? 371 PRO A CA  1 
ATOM   2578  C C   . PRO A 1 351 ? 106.627 151.317 48.866  1.00 205.28 ? 371 PRO A C   1 
ATOM   2579  O O   . PRO A 1 351 ? 105.640 150.584 48.935  1.00 205.28 ? 371 PRO A O   1 
ATOM   2580  C CB  . PRO A 1 351 ? 108.209 151.163 46.897  1.00 206.88 ? 371 PRO A CB  1 
ATOM   2581  C CG  . PRO A 1 351 ? 109.028 152.231 46.194  1.00 206.87 ? 371 PRO A CG  1 
ATOM   2582  C CD  . PRO A 1 351 ? 108.879 153.464 47.063  1.00 205.99 ? 371 PRO A CD  1 
ATOM   2583  N N   . GLN A 1 352 ? 107.386 151.628 49.925  1.00 202.56 ? 372 GLN A N   1 
ATOM   2584  C CA  . GLN A 1 352 ? 107.063 151.143 51.259  1.00 200.18 ? 372 GLN A CA  1 
ATOM   2585  C C   . GLN A 1 352 ? 106.143 152.157 51.931  1.00 195.36 ? 372 GLN A C   1 
ATOM   2586  O O   . GLN A 1 352 ? 106.573 152.929 52.786  1.00 190.88 ? 372 GLN A O   1 
ATOM   2587  C CB  . GLN A 1 352 ? 108.300 150.826 52.112  1.00 201.46 ? 372 GLN A CB  1 
ATOM   2588  C CG  . GLN A 1 352 ? 109.445 151.827 52.025  1.00 201.38 ? 372 GLN A CG  1 
ATOM   2589  C CD  . GLN A 1 352 ? 110.394 151.463 50.909  1.00 200.67 ? 372 GLN A CD  1 
ATOM   2590  O OE1 . GLN A 1 352 ? 109.989 151.329 49.758  1.00 200.54 ? 372 GLN A OE1 1 
ATOM   2591  N NE2 . GLN A 1 352 ? 111.664 151.281 51.241  1.00 198.81 ? 372 GLN A NE2 1 
ATOM   2592  N N   . GLU A 1 353 ? 104.862 152.122 51.542  1.00 193.92 ? 373 GLU A N   1 
ATOM   2593  C CA  . GLU A 1 353 ? 103.852 153.000 52.113  1.00 193.37 ? 373 GLU A CA  1 
ATOM   2594  C C   . GLU A 1 353 ? 103.655 152.663 53.591  1.00 191.43 ? 373 GLU A C   1 
ATOM   2595  O O   . GLU A 1 353 ? 103.629 153.564 54.427  1.00 189.18 ? 373 GLU A O   1 
ATOM   2596  C CB  . GLU A 1 353 ? 102.526 152.872 51.358  1.00 195.52 ? 373 GLU A CB  1 
ATOM   2597  C CG  . GLU A 1 353 ? 102.600 153.311 49.904  1.00 197.39 ? 373 GLU A CG  1 
ATOM   2598  C CD  . GLU A 1 353 ? 101.289 153.219 49.142  1.00 198.64 ? 373 GLU A CD  1 
ATOM   2599  O OE1 . GLU A 1 353 ? 100.282 152.785 49.739  1.00 197.27 ? 373 GLU A OE1 1 
ATOM   2600  O OE2 . GLU A 1 353 ? 101.277 153.583 47.949  1.00 199.31 ? 373 GLU A OE2 1 
ATOM   2601  N N   . ASN A 1 354 ? 103.523 151.364 53.893  1.00 190.22 ? 374 ASN A N   1 
ATOM   2602  C CA  . ASN A 1 354 ? 103.367 150.883 55.257  1.00 188.85 ? 374 ASN A CA  1 
ATOM   2603  C C   . ASN A 1 354 ? 102.081 151.474 55.834  1.00 183.50 ? 374 ASN A C   1 
ATOM   2604  O O   . ASN A 1 354 ? 102.105 152.281 56.762  1.00 181.52 ? 374 ASN A O   1 
ATOM   2605  C CB  . ASN A 1 354 ? 104.610 151.176 56.104  1.00 191.32 ? 374 ASN A CB  1 
ATOM   2606  C CG  . ASN A 1 354 ? 104.693 150.331 57.358  1.00 193.16 ? 374 ASN A CG  1 
ATOM   2607  O OD1 . ASN A 1 354 ? 103.779 149.570 57.666  1.00 192.41 ? 374 ASN A OD1 1 
ATOM   2608  N ND2 . ASN A 1 354 ? 105.795 150.447 58.080  1.00 193.70 ? 374 ASN A ND2 1 
ATOM   2609  N N   . SER A 1 355 ? 100.951 151.013 55.288  1.00 178.59 ? 375 SER A N   1 
ATOM   2610  C CA  . SER A 1 355 ? 99.639  151.574 55.573  1.00 174.69 ? 375 SER A CA  1 
ATOM   2611  C C   . SER A 1 355 ? 99.155  151.238 56.985  1.00 168.87 ? 375 SER A C   1 
ATOM   2612  O O   . SER A 1 355 ? 98.008  151.531 57.317  1.00 168.57 ? 375 SER A O   1 
ATOM   2613  C CB  . SER A 1 355 ? 98.642  151.107 54.539  1.00 175.51 ? 375 SER A CB  1 
ATOM   2614  O OG  . SER A 1 355 ? 98.523  149.691 54.554  1.00 175.84 ? 375 SER A OG  1 
ATOM   2615  N N   . LYS A 1 356 ? 100.014 150.636 57.820  1.00 163.13 ? 376 LYS A N   1 
ATOM   2616  C CA  . LYS A 1 356 ? 99.654  150.333 59.199  1.00 159.86 ? 376 LYS A CA  1 
ATOM   2617  C C   . LYS A 1 356 ? 99.405  151.631 59.966  1.00 152.93 ? 376 LYS A C   1 
ATOM   2618  O O   . LYS A 1 356 ? 98.454  151.727 60.745  1.00 152.77 ? 376 LYS A O   1 
ATOM   2619  C CB  . LYS A 1 356 ? 100.744 149.483 59.865  1.00 161.95 ? 376 LYS A CB  1 
ATOM   2620  C CG  . LYS A 1 356 ? 100.676 149.383 61.384  1.00 163.49 ? 376 LYS A CG  1 
ATOM   2621  C CD  . LYS A 1 356 ? 99.328  148.929 61.913  1.00 165.23 ? 376 LYS A CD  1 
ATOM   2622  C CE  . LYS A 1 356 ? 99.159  149.170 63.399  1.00 166.67 ? 376 LYS A CE  1 
ATOM   2623  N NZ  . LYS A 1 356 ? 97.751  148.984 63.823  1.00 166.91 ? 376 LYS A NZ  1 
ATOM   2624  N N   . TYR A 1 357 ? 100.243 152.641 59.704  1.00 145.79 ? 377 TYR A N   1 
ATOM   2625  C CA  . TYR A 1 357 ? 100.121 153.929 60.367  1.00 141.51 ? 377 TYR A CA  1 
ATOM   2626  C C   . TYR A 1 357 ? 98.920  154.678 59.799  1.00 140.16 ? 377 TYR A C   1 
ATOM   2627  O O   . TYR A 1 357 ? 98.674  154.648 58.594  1.00 139.07 ? 377 TYR A O   1 
ATOM   2628  C CB  . TYR A 1 357 ? 101.408 154.738 60.208  1.00 141.39 ? 377 TYR A CB  1 
ATOM   2629  C CG  . TYR A 1 357 ? 102.651 154.002 60.633  1.00 140.87 ? 377 TYR A CG  1 
ATOM   2630  C CD1 . TYR A 1 357 ? 102.950 153.809 61.972  1.00 140.08 ? 377 TYR A CD1 1 
ATOM   2631  C CD2 . TYR A 1 357 ? 103.505 153.451 59.692  1.00 139.43 ? 377 TYR A CD2 1 
ATOM   2632  C CE1 . TYR A 1 357 ? 104.086 153.121 62.364  1.00 139.02 ? 377 TYR A CE1 1 
ATOM   2633  C CE2 . TYR A 1 357 ? 104.646 152.763 60.067  1.00 137.65 ? 377 TYR A CE2 1 
ATOM   2634  C CZ  . TYR A 1 357 ? 104.942 152.603 61.409  1.00 138.07 ? 377 TYR A CZ  1 
ATOM   2635  O OH  . TYR A 1 357 ? 106.068 151.912 61.779  1.00 137.57 ? 377 TYR A OH  1 
ATOM   2636  N N   . ASN A 1 358 ? 98.185  155.352 60.693  1.00 139.70 ? 378 ASN A N   1 
ATOM   2637  C CA  . ASN A 1 358 ? 96.910  155.963 60.356  1.00 138.82 ? 378 ASN A CA  1 
ATOM   2638  C C   . ASN A 1 358 ? 97.142  157.263 59.588  1.00 138.84 ? 378 ASN A C   1 
ATOM   2639  O O   . ASN A 1 358 ? 96.624  157.428 58.486  1.00 139.34 ? 378 ASN A O   1 
ATOM   2640  C CB  . ASN A 1 358 ? 96.059  156.198 61.608  1.00 139.07 ? 378 ASN A CB  1 
ATOM   2641  C CG  . ASN A 1 358 ? 96.023  154.997 62.531  1.00 139.78 ? 378 ASN A CG  1 
ATOM   2642  O OD1 . ASN A 1 358 ? 96.403  155.096 63.695  1.00 138.44 ? 378 ASN A OD1 1 
ATOM   2643  N ND2 . ASN A 1 358 ? 95.592  153.855 62.018  1.00 139.88 ? 378 ASN A ND2 1 
ATOM   2644  N N   . LYS A 1 359 ? 97.946  158.164 60.166  1.00 138.35 ? 379 LYS A N   1 
ATOM   2645  C CA  . LYS A 1 359 ? 98.102  159.509 59.638  1.00 138.47 ? 379 LYS A CA  1 
ATOM   2646  C C   . LYS A 1 359 ? 99.080  159.505 58.464  1.00 136.34 ? 379 LYS A C   1 
ATOM   2647  O O   . LYS A 1 359 ? 99.768  158.514 58.214  1.00 135.87 ? 379 LYS A O   1 
ATOM   2648  C CB  . LYS A 1 359 ? 98.593  160.471 60.726  1.00 140.60 ? 379 LYS A CB  1 
ATOM   2649  C CG  . LYS A 1 359 ? 97.686  160.629 61.941  1.00 143.70 ? 379 LYS A CG  1 
ATOM   2650  C CD  . LYS A 1 359 ? 97.920  159.601 63.033  1.00 145.10 ? 379 LYS A CD  1 
ATOM   2651  C CE  . LYS A 1 359 ? 97.099  159.861 64.279  1.00 146.05 ? 379 LYS A CE  1 
ATOM   2652  N NZ  . LYS A 1 359 ? 97.343  158.834 65.320  1.00 146.19 ? 379 LYS A NZ  1 
ATOM   2653  N N   . THR A 1 360 ? 99.095  160.626 57.732  1.00 135.40 ? 380 THR A N   1 
ATOM   2654  C CA  . THR A 1 360 ? 100.095 160.899 56.711  1.00 135.13 ? 380 THR A CA  1 
ATOM   2655  C C   . THR A 1 360 ? 100.925 162.091 57.180  1.00 134.52 ? 380 THR A C   1 
ATOM   2656  O O   . THR A 1 360 ? 100.381 163.036 57.751  1.00 135.73 ? 380 THR A O   1 
ATOM   2657  C CB  . THR A 1 360 ? 99.443  161.180 55.349  1.00 135.36 ? 380 THR A CB  1 
ATOM   2658  O OG1 . THR A 1 360 ? 98.632  160.058 54.995  1.00 134.14 ? 380 THR A OG1 1 
ATOM   2659  C CG2 . THR A 1 360 ? 100.453 161.457 54.257  1.00 135.05 ? 380 THR A CG2 1 
ATOM   2660  N N   . CYS A 1 361 ? 102.243 162.036 56.952  1.00 132.59 ? 381 CYS A N   1 
ATOM   2661  C CA  . CYS A 1 361 ? 103.146 163.054 57.477  1.00 132.55 ? 381 CYS A CA  1 
ATOM   2662  C C   . CYS A 1 361 ? 103.429 164.095 56.403  1.00 132.46 ? 381 CYS A C   1 
ATOM   2663  O O   . CYS A 1 361 ? 103.941 163.771 55.334  1.00 129.71 ? 381 CYS A O   1 
ATOM   2664  C CB  . CYS A 1 361 ? 104.468 162.493 57.995  1.00 131.82 ? 381 CYS A CB  1 
ATOM   2665  S SG  . CYS A 1 361 ? 105.216 161.222 56.943  1.00 129.00 ? 381 CYS A SG  1 
ATOM   2666  N N   . ASN A 1 362 ? 103.106 165.343 56.748  1.00 134.98 ? 382 ASN A N   1 
ATOM   2667  C CA  . ASN A 1 362 ? 103.360 166.528 55.947  1.00 136.83 ? 382 ASN A CA  1 
ATOM   2668  C C   . ASN A 1 362 ? 104.857 166.815 55.852  1.00 134.69 ? 382 ASN A C   1 
ATOM   2669  O O   . ASN A 1 362 ? 105.642 166.387 56.695  1.00 133.57 ? 382 ASN A O   1 
ATOM   2670  C CB  . ASN A 1 362 ? 102.619 167.737 56.531  1.00 138.85 ? 382 ASN A CB  1 
ATOM   2671  C CG  . ASN A 1 362 ? 102.810 167.904 58.026  1.00 139.34 ? 382 ASN A CG  1 
ATOM   2672  O OD1 . ASN A 1 362 ? 103.079 169.003 58.504  1.00 138.36 ? 382 ASN A OD1 1 
ATOM   2673  N ND2 . ASN A 1 362 ? 102.630 166.834 58.785  1.00 138.56 ? 382 ASN A ND2 1 
ATOM   2674  N N   . SER A 1 363 ? 105.238 167.575 54.820  1.00 133.31 ? 383 SER A N   1 
ATOM   2675  C CA  . SER A 1 363 ? 106.637 167.855 54.539  1.00 132.87 ? 383 SER A CA  1 
ATOM   2676  C C   . SER A 1 363 ? 107.128 169.018 55.400  1.00 129.69 ? 383 SER A C   1 
ATOM   2677  O O   . SER A 1 363 ? 107.715 169.972 54.891  1.00 130.01 ? 383 SER A O   1 
ATOM   2678  C CB  . SER A 1 363 ? 106.838 168.127 53.068  1.00 135.44 ? 383 SER A CB  1 
ATOM   2679  O OG  . SER A 1 363 ? 106.054 169.232 52.641  1.00 137.13 ? 383 SER A OG  1 
ATOM   2680  N N   . SER A 1 364 ? 106.896 168.921 56.715  1.00 125.72 ? 384 SER A N   1 
ATOM   2681  C CA  . SER A 1 364 ? 107.347 169.938 57.653  1.00 124.17 ? 384 SER A CA  1 
ATOM   2682  C C   . SER A 1 364 ? 107.876 169.308 58.942  1.00 117.86 ? 384 SER A C   1 
ATOM   2683  O O   . SER A 1 364 ? 108.070 170.011 59.932  1.00 117.14 ? 384 SER A O   1 
ATOM   2684  C CB  . SER A 1 364 ? 106.236 170.918 57.939  1.00 127.36 ? 384 SER A CB  1 
ATOM   2685  O OG  . SER A 1 364 ? 105.135 170.272 58.563  1.00 129.30 ? 384 SER A OG  1 
ATOM   2686  N N   . LEU A 1 365 ? 108.111 167.987 58.927  1.00 111.79 ? 385 LEU A N   1 
ATOM   2687  C CA  . LEU A 1 365 ? 108.632 167.277 60.084  1.00 107.99 ? 385 LEU A CA  1 
ATOM   2688  C C   . LEU A 1 365 ? 110.122 167.028 59.874  1.00 98.46  ? 385 LEU A C   1 
ATOM   2689  O O   . LEU A 1 365 ? 110.534 166.599 58.803  1.00 95.49  ? 385 LEU A O   1 
ATOM   2690  C CB  . LEU A 1 365 ? 107.851 165.972 60.282  1.00 112.40 ? 385 LEU A CB  1 
ATOM   2691  C CG  . LEU A 1 365 ? 106.595 166.096 61.148  1.00 119.33 ? 385 LEU A CG  1 
ATOM   2692  C CD1 . LEU A 1 365 ? 105.521 166.929 60.460  1.00 122.61 ? 385 LEU A CD1 1 
ATOM   2693  C CD2 . LEU A 1 365 ? 106.045 164.727 61.511  1.00 119.95 ? 385 LEU A CD2 1 
ATOM   2694  N N   . THR A 1 366 ? 110.914 167.298 60.917  1.00 91.22  ? 386 THR A N   1 
ATOM   2695  C CA  . THR A 1 366 ? 112.365 167.249 60.839  1.00 84.90  ? 386 THR A CA  1 
ATOM   2696  C C   . THR A 1 366 ? 112.915 166.414 61.991  1.00 78.25  ? 386 THR A C   1 
ATOM   2697  O O   . THR A 1 366 ? 112.283 166.310 63.039  1.00 77.77  ? 386 THR A O   1 
ATOM   2698  C CB  . THR A 1 366 ? 112.955 168.664 60.862  1.00 87.35  ? 386 THR A CB  1 
ATOM   2699  O OG1 . THR A 1 366 ? 114.366 168.575 60.664  1.00 87.91  ? 386 THR A OG1 1 
ATOM   2700  C CG2 . THR A 1 366 ? 112.678 169.401 62.156  1.00 88.53  ? 386 THR A CG2 1 
ATOM   2701  N N   . LEU A 1 367 ? 114.121 165.872 61.791  1.00 73.64  ? 387 LEU A N   1 
ATOM   2702  C CA  . LEU A 1 367 ? 114.760 164.996 62.761  1.00 71.72  ? 387 LEU A CA  1 
ATOM   2703  C C   . LEU A 1 367 ? 115.235 165.777 63.984  1.00 73.66  ? 387 LEU A C   1 
ATOM   2704  O O   . LEU A 1 367 ? 115.591 165.168 64.987  1.00 73.72  ? 387 LEU A O   1 
ATOM   2705  C CB  . LEU A 1 367 ? 115.937 164.278 62.091  1.00 70.07  ? 387 LEU A CB  1 
ATOM   2706  C CG  . LEU A 1 367 ? 115.572 163.194 61.077  1.00 69.50  ? 387 LEU A CG  1 
ATOM   2707  C CD1 . LEU A 1 367 ? 116.817 162.615 60.430  1.00 69.45  ? 387 LEU A CD1 1 
ATOM   2708  C CD2 . LEU A 1 367 ? 114.773 162.081 61.730  1.00 69.70  ? 387 LEU A CD2 1 
ATOM   2709  N N   . LYS A 1 368 ? 115.236 167.113 63.900  1.00 76.38  ? 388 LYS A N   1 
ATOM   2710  C CA  . LYS A 1 368 ? 115.744 167.951 64.976  1.00 78.42  ? 388 LYS A CA  1 
ATOM   2711  C C   . LYS A 1 368 ? 114.881 167.785 66.226  1.00 79.18  ? 388 LYS A C   1 
ATOM   2712  O O   . LYS A 1 368 ? 115.394 167.800 67.343  1.00 79.48  ? 388 LYS A O   1 
ATOM   2713  C CB  . LYS A 1 368 ? 115.777 169.417 64.535  1.00 80.01  ? 388 LYS A CB  1 
ATOM   2714  C CG  . LYS A 1 368 ? 116.588 169.694 63.276  1.00 82.32  ? 388 LYS A CG  1 
ATOM   2715  C CD  . LYS A 1 368 ? 116.435 171.106 62.751  1.00 85.92  ? 388 LYS A CD  1 
ATOM   2716  C CE  . LYS A 1 368 ? 116.810 172.173 63.759  1.00 88.23  ? 388 LYS A CE  1 
ATOM   2717  N NZ  . LYS A 1 368 ? 118.170 171.962 64.311  1.00 88.58  ? 388 LYS A NZ  1 
ATOM   2718  N N   . THR A 1 369 ? 113.570 167.616 66.024  1.00 79.24  ? 389 THR A N   1 
ATOM   2719  C CA  . THR A 1 369 ? 112.629 167.498 67.125  1.00 79.81  ? 389 THR A CA  1 
ATOM   2720  C C   . THR A 1 369 ? 112.917 166.215 67.901  1.00 79.11  ? 389 THR A C   1 
ATOM   2721  O O   . THR A 1 369 ? 112.817 165.126 67.344  1.00 78.78  ? 389 THR A O   1 
ATOM   2722  C CB  . THR A 1 369 ? 111.183 167.524 66.611  1.00 81.34  ? 389 THR A CB  1 
ATOM   2723  O OG1 . THR A 1 369 ? 110.965 166.350 65.827  1.00 81.89  ? 389 THR A OG1 1 
ATOM   2724  C CG2 . THR A 1 369 ? 110.870 168.750 65.782  1.00 82.45  ? 389 THR A CG2 1 
ATOM   2725  N N   . HIS A 1 370 ? 113.284 166.358 69.180  1.00 79.92  ? 390 HIS A N   1 
ATOM   2726  C CA  . HIS A 1 370 ? 113.555 165.228 70.056  1.00 81.13  ? 390 HIS A CA  1 
ATOM   2727  C C   . HIS A 1 370 ? 114.688 164.382 69.480  1.00 75.40  ? 390 HIS A C   1 
ATOM   2728  O O   . HIS A 1 370 ? 114.529 163.178 69.280  1.00 75.60  ? 390 HIS A O   1 
ATOM   2729  C CB  . HIS A 1 370 ? 112.297 164.377 70.275  1.00 87.43  ? 390 HIS A CB  1 
ATOM   2730  C CG  . HIS A 1 370 ? 111.033 165.159 70.369  1.00 96.00  ? 390 HIS A CG  1 
ATOM   2731  N ND1 . HIS A 1 370 ? 109.820 164.664 69.935  1.00 100.69 ? 390 HIS A ND1 1 
ATOM   2732  C CD2 . HIS A 1 370 ? 110.772 166.362 70.899  1.00 101.06 ? 390 HIS A CD2 1 
ATOM   2733  C CE1 . HIS A 1 370 ? 108.873 165.564 70.162  1.00 103.99 ? 390 HIS A CE1 1 
ATOM   2734  N NE2 . HIS A 1 370 ? 109.431 166.604 70.746  1.00 103.96 ? 390 HIS A NE2 1 
ATOM   2735  N N   . HIS A 1 371 ? 115.831 165.027 69.220  1.00 70.35  ? 391 HIS A N   1 
ATOM   2736  C CA  . HIS A 1 371 ? 116.992 164.348 68.668  1.00 66.25  ? 391 HIS A CA  1 
ATOM   2737  C C   . HIS A 1 371 ? 118.008 164.062 69.767  1.00 62.30  ? 391 HIS A C   1 
ATOM   2738  O O   . HIS A 1 371 ? 118.378 164.961 70.519  1.00 62.28  ? 391 HIS A O   1 
ATOM   2739  C CB  . HIS A 1 371 ? 117.665 165.199 67.588  1.00 66.15  ? 391 HIS A CB  1 
ATOM   2740  C CG  . HIS A 1 371 ? 118.952 164.620 67.102  1.00 66.42  ? 391 HIS A CG  1 
ATOM   2741  N ND1 . HIS A 1 371 ? 119.041 163.390 66.488  1.00 65.89  ? 391 HIS A ND1 1 
ATOM   2742  C CD2 . HIS A 1 371 ? 120.199 165.101 67.151  1.00 67.24  ? 391 HIS A CD2 1 
ATOM   2743  C CE1 . HIS A 1 371 ? 120.306 163.152 66.174  1.00 66.16  ? 391 HIS A CE1 1 
ATOM   2744  N NE2 . HIS A 1 371 ? 121.025 164.178 66.566  1.00 67.12  ? 391 HIS A NE2 1 
ATOM   2745  N N   . VAL A 1 372 ? 118.462 162.805 69.832  1.00 58.54  ? 392 VAL A N   1 
ATOM   2746  C CA  . VAL A 1 372 ? 119.596 162.438 70.660  1.00 55.63  ? 392 VAL A CA  1 
ATOM   2747  C C   . VAL A 1 372 ? 120.567 161.633 69.802  1.00 52.52  ? 392 VAL A C   1 
ATOM   2748  O O   . VAL A 1 372 ? 120.157 160.772 69.026  1.00 51.70  ? 392 VAL A O   1 
ATOM   2749  C CB  . VAL A 1 372 ? 119.159 161.659 71.915  1.00 56.10  ? 392 VAL A CB  1 
ATOM   2750  C CG1 . VAL A 1 372 ? 118.914 160.187 71.623  1.00 55.62  ? 392 VAL A CG1 1 
ATOM   2751  C CG2 . VAL A 1 372 ? 120.161 161.817 73.047  1.00 56.87  ? 392 VAL A CG2 1 
ATOM   2752  N N   . GLN A 1 373 ? 121.857 161.951 69.933  1.00 49.97  ? 393 GLN A N   1 
ATOM   2753  C CA  . GLN A 1 373 ? 122.903 161.218 69.242  1.00 47.84  ? 393 GLN A CA  1 
ATOM   2754  C C   . GLN A 1 373 ? 123.388 160.096 70.152  1.00 45.16  ? 393 GLN A C   1 
ATOM   2755  O O   . GLN A 1 373 ? 123.609 160.318 71.339  1.00 46.06  ? 393 GLN A O   1 
ATOM   2756  C CB  . GLN A 1 373 ? 124.059 162.145 68.874  1.00 48.48  ? 393 GLN A CB  1 
ATOM   2757  C CG  . GLN A 1 373 ? 125.208 161.421 68.191  1.00 49.08  ? 393 GLN A CG  1 
ATOM   2758  C CD  . GLN A 1 373 ? 126.374 162.332 67.905  1.00 49.83  ? 393 GLN A CD  1 
ATOM   2759  O OE1 . GLN A 1 373 ? 127.514 162.033 68.250  1.00 50.35  ? 393 GLN A OE1 1 
ATOM   2760  N NE2 . GLN A 1 373 ? 126.101 163.443 67.245  1.00 50.08  ? 393 GLN A NE2 1 
ATOM   2761  N N   . ASP A 1 374 ? 123.575 158.905 69.582  1.00 42.13  ? 394 ASP A N   1 
ATOM   2762  C CA  . ASP A 1 374 ? 123.954 157.738 70.360  1.00 41.27  ? 394 ASP A CA  1 
ATOM   2763  C C   . ASP A 1 374 ? 125.330 157.970 70.978  1.00 39.76  ? 394 ASP A C   1 
ATOM   2764  O O   . ASP A 1 374 ? 126.191 158.615 70.383  1.00 39.82  ? 394 ASP A O   1 
ATOM   2765  C CB  . ASP A 1 374 ? 123.941 156.483 69.485  1.00 41.94  ? 394 ASP A CB  1 
ATOM   2766  C CG  . ASP A 1 374 ? 124.820 156.655 68.261  1.00 42.27  ? 394 ASP A CG  1 
ATOM   2767  O OD1 . ASP A 1 374 ? 124.703 157.719 67.621  1.00 41.85  ? 394 ASP A OD1 1 
ATOM   2768  O OD2 . ASP A 1 374 ? 125.566 155.713 67.927  1.00 42.23  ? 394 ASP A OD2 1 
ATOM   2769  N N   . SER A 1 375 ? 125.526 157.431 72.183  1.00 38.95  ? 395 SER A N   1 
ATOM   2770  C CA  . SER A 1 375 ? 126.693 157.763 72.983  1.00 38.34  ? 395 SER A CA  1 
ATOM   2771  C C   . SER A 1 375 ? 127.965 157.199 72.357  1.00 36.76  ? 395 SER A C   1 
ATOM   2772  O O   . SER A 1 375 ? 129.041 157.755 72.556  1.00 37.81  ? 395 SER A O   1 
ATOM   2773  C CB  . SER A 1 375 ? 126.527 157.300 74.406  1.00 39.14  ? 395 SER A CB  1 
ATOM   2774  O OG  . SER A 1 375 ? 126.062 155.962 74.455  1.00 39.85  ? 395 SER A OG  1 
ATOM   2775  N N   . LYS A 1 376 ? 127.842 156.108 71.590  1.00 35.08  ? 396 LYS A N   1 
ATOM   2776  C CA  . LYS A 1 376 ? 129.014 155.418 71.069  1.00 33.73  ? 396 LYS A CA  1 
ATOM   2777  C C   . LYS A 1 376 ? 129.218 155.741 69.588  1.00 32.39  ? 396 LYS A C   1 
ATOM   2778  O O   . LYS A 1 376 ? 129.747 154.921 68.840  1.00 32.04  ? 396 LYS A O   1 
ATOM   2779  C CB  . LYS A 1 376 ? 128.885 153.904 71.260  1.00 33.60  ? 396 LYS A CB  1 
ATOM   2780  C CG  . LYS A 1 376 ? 128.336 153.457 72.607  1.00 34.33  ? 396 LYS A CG  1 
ATOM   2781  C CD  . LYS A 1 376 ? 128.434 151.976 72.855  1.00 34.71  ? 396 LYS A CD  1 
ATOM   2782  C CE  . LYS A 1 376 ? 129.809 151.548 73.316  1.00 35.29  ? 396 LYS A CE  1 
ATOM   2783  N NZ  . LYS A 1 376 ? 130.183 152.207 74.588  1.00 35.68  ? 396 LYS A NZ  1 
ATOM   2784  N N   . MET A 1 377 ? 128.804 156.943 69.169  1.00 31.57  ? 397 MET A N   1 
ATOM   2785  C CA  . MET A 1 377 ? 128.944 157.378 67.791  1.00 31.13  ? 397 MET A CA  1 
ATOM   2786  C C   . MET A 1 377 ? 130.419 157.629 67.496  1.00 30.34  ? 397 MET A C   1 
ATOM   2787  O O   . MET A 1 377 ? 130.922 157.214 66.454  1.00 30.40  ? 397 MET A O   1 
ATOM   2788  C CB  . MET A 1 377 ? 128.153 158.670 67.558  1.00 32.06  ? 397 MET A CB  1 
ATOM   2789  C CG  . MET A 1 377 ? 128.435 159.358 66.228  1.00 32.53  ? 397 MET A CG  1 
ATOM   2790  S SD  . MET A 1 377 ? 128.096 158.314 64.798  1.00 33.58  ? 397 MET A SD  1 
ATOM   2791  C CE  . MET A 1 377 ? 126.507 157.631 65.253  1.00 33.46  ? 397 MET A CE  1 
ATOM   2792  N N   . GLY A 1 378 ? 131.096 158.326 68.418  1.00 29.43  ? 398 GLY A N   1 
ATOM   2793  C CA  . GLY A 1 378 ? 132.503 158.648 68.257  1.00 28.52  ? 398 GLY A CA  1 
ATOM   2794  C C   . GLY A 1 378 ? 133.321 157.405 67.930  1.00 27.72  ? 398 GLY A C   1 
ATOM   2795  O O   . GLY A 1 378 ? 134.057 157.381 66.939  1.00 27.85  ? 398 GLY A O   1 
ATOM   2796  N N   . PHE A 1 379 ? 133.113 156.349 68.727  1.00 26.83  ? 399 PHE A N   1 
ATOM   2797  C CA  . PHE A 1 379 ? 133.846 155.106 68.559  1.00 26.14  ? 399 PHE A CA  1 
ATOM   2798  C C   . PHE A 1 379 ? 133.635 154.549 67.157  1.00 25.14  ? 399 PHE A C   1 
ATOM   2799  O O   . PHE A 1 379 ? 134.607 154.180 66.511  1.00 25.90  ? 399 PHE A O   1 
ATOM   2800  C CB  . PHE A 1 379 ? 133.436 154.079 69.611  1.00 26.81  ? 399 PHE A CB  1 
ATOM   2801  C CG  . PHE A 1 379 ? 133.704 154.522 71.024  1.00 28.04  ? 399 PHE A CG  1 
ATOM   2802  C CD1 . PHE A 1 379 ? 134.987 154.849 71.427  1.00 28.83  ? 399 PHE A CD1 1 
ATOM   2803  C CD2 . PHE A 1 379 ? 132.673 154.633 71.943  1.00 29.09  ? 399 PHE A CD2 1 
ATOM   2804  C CE1 . PHE A 1 379 ? 135.238 155.260 72.727  1.00 29.77  ? 399 PHE A CE1 1 
ATOM   2805  C CE2 . PHE A 1 379 ? 132.925 155.042 73.244  1.00 29.93  ? 399 PHE A CE2 1 
ATOM   2806  C CZ  . PHE A 1 379 ? 134.206 155.359 73.631  1.00 30.25  ? 399 PHE A CZ  1 
ATOM   2807  N N   . VAL A 1 380 ? 132.394 154.574 66.667  1.00 24.51  ? 400 VAL A N   1 
ATOM   2808  C CA  . VAL A 1 380 ? 132.105 154.065 65.338  1.00 24.24  ? 400 VAL A CA  1 
ATOM   2809  C C   . VAL A 1 380 ? 132.958 154.806 64.313  1.00 24.59  ? 400 VAL A C   1 
ATOM   2810  O O   . VAL A 1 380 ? 133.631 154.175 63.497  1.00 25.15  ? 400 VAL A O   1 
ATOM   2811  C CB  . VAL A 1 380 ? 130.604 154.163 65.007  1.00 24.05  ? 400 VAL A CB  1 
ATOM   2812  C CG1 . VAL A 1 380 ? 130.326 153.911 63.532  1.00 23.83  ? 400 VAL A CG1 1 
ATOM   2813  C CG2 . VAL A 1 380 ? 129.782 153.228 65.879  1.00 24.06  ? 400 VAL A CG2 1 
ATOM   2814  N N   . ILE A 1 381 ? 132.961 156.139 64.381  1.00 25.07  ? 401 ILE A N   1 
ATOM   2815  C CA  . ILE A 1 381 ? 133.729 156.922 63.429  1.00 25.77  ? 401 ILE A CA  1 
ATOM   2816  C C   . ILE A 1 381 ? 135.207 156.567 63.574  1.00 25.85  ? 401 ILE A C   1 
ATOM   2817  O O   . ILE A 1 381 ? 135.882 156.294 62.585  1.00 26.54  ? 401 ILE A O   1 
ATOM   2818  C CB  . ILE A 1 381 ? 133.494 158.433 63.594  1.00 27.04  ? 401 ILE A CB  1 
ATOM   2819  C CG1 . ILE A 1 381 ? 132.008 158.795 63.623  1.00 27.71  ? 401 ILE A CG1 1 
ATOM   2820  C CG2 . ILE A 1 381 ? 134.223 159.190 62.496  1.00 27.56  ? 401 ILE A CG2 1 
ATOM   2821  C CD1 . ILE A 1 381 ? 131.292 158.585 62.307  1.00 28.32  ? 401 ILE A CD1 1 
ATOM   2822  N N   . ASN A 1 382 ? 135.684 156.498 64.821  1.00 25.82  ? 402 ASN A N   1 
ATOM   2823  C CA  . ASN A 1 382 ? 137.064 156.130 65.087  1.00 25.85  ? 402 ASN A CA  1 
ATOM   2824  C C   . ASN A 1 382 ? 137.395 154.801 64.413  1.00 25.98  ? 402 ASN A C   1 
ATOM   2825  O O   . ASN A 1 382 ? 138.377 154.716 63.685  1.00 26.94  ? 402 ASN A O   1 
ATOM   2826  C CB  . ASN A 1 382 ? 137.368 156.081 66.583  1.00 26.07  ? 402 ASN A CB  1 
ATOM   2827  C CG  . ASN A 1 382 ? 137.592 157.457 67.170  1.00 26.67  ? 402 ASN A CG  1 
ATOM   2828  O OD1 . ASN A 1 382 ? 137.565 158.459 66.455  1.00 27.46  ? 402 ASN A OD1 1 
ATOM   2829  N ND2 . ASN A 1 382 ? 137.832 157.511 68.470  1.00 26.96  ? 402 ASN A ND2 1 
ATOM   2830  N N   . ALA A 1 383 ? 136.530 153.799 64.590  1.00 25.83  ? 403 ALA A N   1 
ATOM   2831  C CA  . ALA A 1 383 ? 136.764 152.482 64.027  1.00 25.93  ? 403 ALA A CA  1 
ATOM   2832  C C   . ALA A 1 383 ? 136.947 152.573 62.516  1.00 26.70  ? 403 ALA A C   1 
ATOM   2833  O O   . ALA A 1 383 ? 137.894 152.005 61.974  1.00 27.97  ? 403 ALA A O   1 
ATOM   2834  C CB  . ALA A 1 383 ? 135.641 151.544 64.393  1.00 25.94  ? 403 ALA A CB  1 
ATOM   2835  N N   . ILE A 1 384 ? 136.070 153.316 61.841  1.00 27.48  ? 404 ILE A N   1 
ATOM   2836  C CA  . ILE A 1 384 ? 136.170 153.420 60.398  1.00 28.99  ? 404 ILE A CA  1 
ATOM   2837  C C   . ILE A 1 384 ? 137.476 154.124 60.035  1.00 30.43  ? 404 ILE A C   1 
ATOM   2838  O O   . ILE A 1 384 ? 138.192 153.664 59.147  1.00 30.92  ? 404 ILE A O   1 
ATOM   2839  C CB  . ILE A 1 384 ? 134.935 154.119 59.809  1.00 29.88  ? 404 ILE A CB  1 
ATOM   2840  C CG1 . ILE A 1 384 ? 133.668 153.301 60.071  1.00 30.71  ? 404 ILE A CG1 1 
ATOM   2841  C CG2 . ILE A 1 384 ? 135.129 154.399 58.327  1.00 29.98  ? 404 ILE A CG2 1 
ATOM   2842  C CD1 . ILE A 1 384 ? 132.410 154.124 60.136  1.00 31.51  ? 404 ILE A CD1 1 
ATOM   2843  N N   . TYR A 1 385 ? 137.791 155.224 60.732  1.00 32.30  ? 405 TYR A N   1 
ATOM   2844  C CA  . TYR A 1 385 ? 139.061 155.903 60.523  1.00 33.98  ? 405 TYR A CA  1 
ATOM   2845  C C   . TYR A 1 385 ? 140.225 154.954 60.800  1.00 34.69  ? 405 TYR A C   1 
ATOM   2846  O O   . TYR A 1 385 ? 141.196 154.919 60.053  1.00 35.57  ? 405 TYR A O   1 
ATOM   2847  C CB  . TYR A 1 385 ? 139.195 157.154 61.396  1.00 35.11  ? 405 TYR A CB  1 
ATOM   2848  C CG  . TYR A 1 385 ? 138.626 158.412 60.794  1.00 36.80  ? 405 TYR A CG  1 
ATOM   2849  C CD1 . TYR A 1 385 ? 138.826 158.722 59.460  1.00 37.75  ? 405 TYR A CD1 1 
ATOM   2850  C CD2 . TYR A 1 385 ? 137.929 159.325 61.569  1.00 38.67  ? 405 TYR A CD2 1 
ATOM   2851  C CE1 . TYR A 1 385 ? 138.320 159.885 58.903  1.00 38.87  ? 405 TYR A CE1 1 
ATOM   2852  C CE2 . TYR A 1 385 ? 137.412 160.490 61.028  1.00 39.67  ? 405 TYR A CE2 1 
ATOM   2853  C CZ  . TYR A 1 385 ? 137.601 160.768 59.687  1.00 39.79  ? 405 TYR A CZ  1 
ATOM   2854  O OH  . TYR A 1 385 ? 137.093 161.922 59.144  1.00 40.49  ? 405 TYR A OH  1 
ATOM   2855  N N   . SER A 1 386 ? 140.097 154.150 61.857  1.00 35.18  ? 406 SER A N   1 
ATOM   2856  C CA  . SER A 1 386 ? 141.135 153.211 62.240  1.00 35.68  ? 406 SER A CA  1 
ATOM   2857  C C   . SER A 1 386 ? 141.442 152.261 61.088  1.00 36.31  ? 406 SER A C   1 
ATOM   2858  O O   . SER A 1 386 ? 142.599 151.914 60.877  1.00 37.30  ? 406 SER A O   1 
ATOM   2859  C CB  . SER A 1 386 ? 140.759 152.482 63.499  1.00 35.77  ? 406 SER A CB  1 
ATOM   2860  O OG  . SER A 1 386 ? 141.594 151.356 63.708  1.00 36.37  ? 406 SER A OG  1 
ATOM   2861  N N   . MET A 1 387 ? 140.415 151.875 60.327  1.00 37.70  ? 407 MET A N   1 
ATOM   2862  C CA  . MET A 1 387 ? 140.638 151.051 59.154  1.00 39.43  ? 407 MET A CA  1 
ATOM   2863  C C   . MET A 1 387 ? 141.337 151.877 58.074  1.00 41.07  ? 407 MET A C   1 
ATOM   2864  O O   . MET A 1 387 ? 142.319 151.421 57.493  1.00 41.82  ? 407 MET A O   1 
ATOM   2865  C CB  . MET A 1 387 ? 139.331 150.481 58.592  1.00 40.04  ? 407 MET A CB  1 
ATOM   2866  C CG  . MET A 1 387 ? 139.546 149.566 57.394  1.00 40.70  ? 407 MET A CG  1 
ATOM   2867  S SD  . MET A 1 387 ? 140.163 147.940 57.881  1.00 41.44  ? 407 MET A SD  1 
ATOM   2868  C CE  . MET A 1 387 ? 138.588 147.167 58.223  1.00 40.54  ? 407 MET A CE  1 
ATOM   2869  N N   . ALA A 1 388 ? 140.792 153.058 57.764  1.00 43.04  ? 408 ALA A N   1 
ATOM   2870  C CA  . ALA A 1 388 ? 141.265 153.841 56.633  1.00 44.73  ? 408 ALA A CA  1 
ATOM   2871  C C   . ALA A 1 388 ? 142.742 154.180 56.821  1.00 46.92  ? 408 ALA A C   1 
ATOM   2872  O O   . ALA A 1 388 ? 143.562 153.902 55.952  1.00 47.60  ? 408 ALA A O   1 
ATOM   2873  C CB  . ALA A 1 388 ? 140.425 155.081 56.474  1.00 44.70  ? 408 ALA A CB  1 
ATOM   2874  N N   . TYR A 1 389 ? 143.089 154.739 57.987  1.00 49.48  ? 409 TYR A N   1 
ATOM   2875  C CA  . TYR A 1 389 ? 144.479 155.029 58.300  1.00 52.51  ? 409 TYR A CA  1 
ATOM   2876  C C   . TYR A 1 389 ? 145.343 153.784 58.125  1.00 53.79  ? 409 TYR A C   1 
ATOM   2877  O O   . TYR A 1 389 ? 146.430 153.871 57.561  1.00 55.72  ? 409 TYR A O   1 
ATOM   2878  C CB  . TYR A 1 389 ? 144.639 155.572 59.719  1.00 54.78  ? 409 TYR A CB  1 
ATOM   2879  C CG  . TYR A 1 389 ? 144.535 157.069 59.822  1.00 58.59  ? 409 TYR A CG  1 
ATOM   2880  C CD1 . TYR A 1 389 ? 143.303 157.697 59.829  1.00 61.35  ? 409 TYR A CD1 1 
ATOM   2881  C CD2 . TYR A 1 389 ? 145.670 157.862 59.883  1.00 61.45  ? 409 TYR A CD2 1 
ATOM   2882  C CE1 . TYR A 1 389 ? 143.198 159.074 59.944  1.00 63.76  ? 409 TYR A CE1 1 
ATOM   2883  C CE2 . TYR A 1 389 ? 145.584 159.240 59.983  1.00 63.70  ? 409 TYR A CE2 1 
ATOM   2884  C CZ  . TYR A 1 389 ? 144.342 159.849 60.014  1.00 65.13  ? 409 TYR A CZ  1 
ATOM   2885  O OH  . TYR A 1 389 ? 144.248 161.218 60.101  1.00 66.67  ? 409 TYR A OH  1 
ATOM   2886  N N   . GLY A 1 390 ? 144.845 152.639 58.602  1.00 53.97  ? 410 GLY A N   1 
ATOM   2887  C CA  . GLY A 1 390 ? 145.526 151.370 58.429  1.00 54.17  ? 410 GLY A CA  1 
ATOM   2888  C C   . GLY A 1 390 ? 145.881 151.090 56.976  1.00 54.91  ? 410 GLY A C   1 
ATOM   2889  O O   . GLY A 1 390 ? 147.046 150.903 56.646  1.00 56.39  ? 410 GLY A O   1 
ATOM   2890  N N   . LEU A 1 391 ? 144.869 151.099 56.108  1.00 56.27  ? 411 LEU A N   1 
ATOM   2891  C CA  . LEU A 1 391 ? 145.086 150.951 54.679  1.00 57.95  ? 411 LEU A CA  1 
ATOM   2892  C C   . LEU A 1 391 ? 146.111 151.983 54.213  1.00 60.63  ? 411 LEU A C   1 
ATOM   2893  O O   . LEU A 1 391 ? 147.070 151.625 53.536  1.00 62.13  ? 411 LEU A O   1 
ATOM   2894  C CB  . LEU A 1 391 ? 143.755 151.103 53.936  1.00 58.28  ? 411 LEU A CB  1 
ATOM   2895  C CG  . LEU A 1 391 ? 142.828 149.889 53.987  1.00 58.20  ? 411 LEU A CG  1 
ATOM   2896  C CD1 . LEU A 1 391 ? 141.441 150.236 53.477  1.00 58.44  ? 411 LEU A CD1 1 
ATOM   2897  C CD2 . LEU A 1 391 ? 143.405 148.735 53.183  1.00 58.78  ? 411 LEU A CD2 1 
ATOM   2898  N N   . HIS A 1 392 ? 145.950 153.237 54.651  1.00 63.27  ? 412 HIS A N   1 
ATOM   2899  C CA  . HIS A 1 392 ? 146.858 154.312 54.289  1.00 66.65  ? 412 HIS A CA  1 
ATOM   2900  C C   . HIS A 1 392 ? 148.302 153.969 54.651  1.00 67.94  ? 412 HIS A C   1 
ATOM   2901  O O   . HIS A 1 392 ? 149.200 154.130 53.830  1.00 70.53  ? 412 HIS A O   1 
ATOM   2902  C CB  . HIS A 1 392 ? 146.456 155.631 54.957  1.00 69.32  ? 412 HIS A CB  1 
ATOM   2903  C CG  . HIS A 1 392 ? 147.323 156.782 54.568  1.00 72.27  ? 412 HIS A CG  1 
ATOM   2904  N ND1 . HIS A 1 392 ? 147.345 157.286 53.286  1.00 74.16  ? 412 HIS A ND1 1 
ATOM   2905  C CD2 . HIS A 1 392 ? 148.189 157.521 55.276  1.00 73.91  ? 412 HIS A CD2 1 
ATOM   2906  C CE1 . HIS A 1 392 ? 148.205 158.293 53.230  1.00 75.85  ? 412 HIS A CE1 1 
ATOM   2907  N NE2 . HIS A 1 392 ? 148.726 158.454 54.428  1.00 75.51  ? 412 HIS A NE2 1 
ATOM   2908  N N   . ASN A 1 393 ? 148.525 153.497 55.880  1.00 67.93  ? 413 ASN A N   1 
ATOM   2909  C CA  . ASN A 1 393 ? 149.864 153.147 56.324  1.00 67.87  ? 413 ASN A CA  1 
ATOM   2910  C C   . ASN A 1 393 ? 150.412 152.017 55.459  1.00 69.65  ? 413 ASN A C   1 
ATOM   2911  O O   . ASN A 1 393 ? 151.555 152.082 55.022  1.00 71.88  ? 413 ASN A O   1 
ATOM   2912  C CB  . ASN A 1 393 ? 149.891 152.819 57.817  1.00 67.17  ? 413 ASN A CB  1 
ATOM   2913  C CG  . ASN A 1 393 ? 149.662 154.047 58.672  1.00 67.68  ? 413 ASN A CG  1 
ATOM   2914  O OD1 . ASN A 1 393 ? 149.297 155.105 58.163  1.00 67.70  ? 413 ASN A OD1 1 
ATOM   2915  N ND2 . ASN A 1 393 ? 149.879 153.920 59.972  1.00 67.92  ? 413 ASN A ND2 1 
ATOM   2916  N N   . MET A 1 394 ? 149.589 151.000 55.189  1.00 72.95  ? 414 MET A N   1 
ATOM   2917  C CA  . MET A 1 394 ? 149.983 149.927 54.289  1.00 77.24  ? 414 MET A CA  1 
ATOM   2918  C C   . MET A 1 394 ? 150.351 150.519 52.928  1.00 82.19  ? 414 MET A C   1 
ATOM   2919  O O   . MET A 1 394 ? 151.366 150.147 52.355  1.00 85.14  ? 414 MET A O   1 
ATOM   2920  C CB  . MET A 1 394 ? 148.873 148.880 54.132  1.00 77.27  ? 414 MET A CB  1 
ATOM   2921  C CG  . MET A 1 394 ? 148.941 148.082 52.836  1.00 77.75  ? 414 MET A CG  1 
ATOM   2922  S SD  . MET A 1 394 ? 147.441 147.112 52.505  1.00 77.99  ? 414 MET A SD  1 
ATOM   2923  C CE  . MET A 1 394 ? 147.539 145.831 53.755  1.00 77.31  ? 414 MET A CE  1 
ATOM   2924  N N   . GLN A 1 395 ? 149.537 151.457 52.432  1.00 86.69  ? 415 GLN A N   1 
ATOM   2925  C CA  . GLN A 1 395 ? 149.765 152.093 51.144  1.00 92.07  ? 415 GLN A CA  1 
ATOM   2926  C C   . GLN A 1 395 ? 151.134 152.768 51.131  1.00 95.25  ? 415 GLN A C   1 
ATOM   2927  O O   . GLN A 1 395 ? 151.846 152.705 50.136  1.00 95.23  ? 415 GLN A O   1 
ATOM   2928  C CB  . GLN A 1 395 ? 148.632 153.080 50.839  1.00 95.48  ? 415 GLN A CB  1 
ATOM   2929  C CG  . GLN A 1 395 ? 148.813 153.848 49.538  1.00 97.88  ? 415 GLN A CG  1 
ATOM   2930  C CD  . GLN A 1 395 ? 149.174 152.923 48.403  1.00 101.15 ? 415 GLN A CD  1 
ATOM   2931  O OE1 . GLN A 1 395 ? 148.310 152.292 47.796  1.00 102.10 ? 415 GLN A OE1 1 
ATOM   2932  N NE2 . GLN A 1 395 ? 150.455 152.858 48.079  1.00 103.51 ? 415 GLN A NE2 1 
ATOM   2933  N N   . MET A 1 396 ? 151.496 153.417 52.241  1.00 100.24 ? 416 MET A N   1 
ATOM   2934  C CA  . MET A 1 396 ? 152.761 154.123 52.321  1.00 106.09 ? 416 MET A CA  1 
ATOM   2935  C C   . MET A 1 396 ? 153.917 153.126 52.411  1.00 109.69 ? 416 MET A C   1 
ATOM   2936  O O   . MET A 1 396 ? 154.982 153.391 51.860  1.00 111.49 ? 416 MET A O   1 
ATOM   2937  C CB  . MET A 1 396 ? 152.784 155.073 53.524  1.00 109.76 ? 416 MET A CB  1 
ATOM   2938  C CG  . MET A 1 396 ? 152.092 156.397 53.247  1.00 112.20 ? 416 MET A CG  1 
ATOM   2939  S SD  . MET A 1 396 ? 152.529 157.693 54.438  1.00 115.91 ? 416 MET A SD  1 
ATOM   2940  C CE  . MET A 1 396 ? 152.472 156.776 55.977  1.00 116.04 ? 416 MET A CE  1 
ATOM   2941  N N   . SER A 1 397 ? 153.706 151.990 53.090  1.00 113.58 ? 417 SER A N   1 
ATOM   2942  C CA  . SER A 1 397 ? 154.787 151.069 53.405  1.00 117.43 ? 417 SER A CA  1 
ATOM   2943  C C   . SER A 1 397 ? 155.026 150.049 52.291  1.00 121.08 ? 417 SER A C   1 
ATOM   2944  O O   . SER A 1 397 ? 156.142 149.540 52.176  1.00 121.92 ? 417 SER A O   1 
ATOM   2945  C CB  . SER A 1 397 ? 154.529 150.379 54.721  1.00 117.67 ? 417 SER A CB  1 
ATOM   2946  O OG  . SER A 1 397 ? 154.573 151.313 55.790  1.00 118.30 ? 417 SER A OG  1 
ATOM   2947  N N   . LEU A 1 398 ? 153.992 149.725 51.497  1.00 125.18 ? 418 LEU A N   1 
ATOM   2948  C CA  . LEU A 1 398 ? 154.092 148.636 50.531  1.00 129.79 ? 418 LEU A CA  1 
ATOM   2949  C C   . LEU A 1 398 ? 154.556 149.154 49.168  1.00 134.09 ? 418 LEU A C   1 
ATOM   2950  O O   . LEU A 1 398 ? 155.340 148.492 48.492  1.00 134.45 ? 418 LEU A O   1 
ATOM   2951  C CB  . LEU A 1 398 ? 152.741 147.916 50.431  1.00 131.18 ? 418 LEU A CB  1 
ATOM   2952  C CG  . LEU A 1 398 ? 152.778 146.496 49.866  1.00 131.69 ? 418 LEU A CG  1 
ATOM   2953  C CD1 . LEU A 1 398 ? 153.651 145.591 50.720  1.00 131.91 ? 418 LEU A CD1 1 
ATOM   2954  C CD2 . LEU A 1 398 ? 151.374 145.916 49.751  1.00 130.86 ? 418 LEU A CD2 1 
ATOM   2955  N N   . CYS A 1 399 ? 154.044 150.317 48.750  1.00 140.04 ? 419 CYS A N   1 
ATOM   2956  C CA  . CYS A 1 399 ? 154.491 150.970 47.528  1.00 147.50 ? 419 CYS A CA  1 
ATOM   2957  C C   . CYS A 1 399 ? 154.491 152.476 47.757  1.00 153.42 ? 419 CYS A C   1 
ATOM   2958  O O   . CYS A 1 399 ? 153.531 153.162 47.405  1.00 153.51 ? 419 CYS A O   1 
ATOM   2959  C CB  . CYS A 1 399 ? 153.632 150.610 46.321  1.00 149.86 ? 419 CYS A CB  1 
ATOM   2960  S SG  . CYS A 1 399 ? 151.882 150.375 46.716  1.00 153.27 ? 419 CYS A SG  1 
ATOM   2961  N N   . PRO A 1 400 ? 155.577 153.032 48.339  1.00 161.37 ? 420 PRO A N   1 
ATOM   2962  C CA  . PRO A 1 400 ? 155.645 154.458 48.666  1.00 166.07 ? 420 PRO A CA  1 
ATOM   2963  C C   . PRO A 1 400 ? 155.461 155.388 47.467  1.00 171.34 ? 420 PRO A C   1 
ATOM   2964  O O   . PRO A 1 400 ? 154.796 156.411 47.589  1.00 172.96 ? 420 PRO A O   1 
ATOM   2965  C CB  . PRO A 1 400 ? 157.058 154.638 49.251  1.00 164.55 ? 420 PRO A CB  1 
ATOM   2966  C CG  . PRO A 1 400 ? 157.477 153.250 49.685  1.00 163.20 ? 420 PRO A CG  1 
ATOM   2967  C CD  . PRO A 1 400 ? 156.812 152.320 48.696  1.00 162.16 ? 420 PRO A CD  1 
ATOM   2968  N N   . GLY A 1 401 ? 156.048 155.016 46.321  1.00 175.55 ? 421 GLY A N   1 
ATOM   2969  C CA  . GLY A 1 401 ? 156.103 155.879 45.153  1.00 180.81 ? 421 GLY A CA  1 
ATOM   2970  C C   . GLY A 1 401 ? 154.726 156.202 44.576  1.00 185.67 ? 421 GLY A C   1 
ATOM   2971  O O   . GLY A 1 401 ? 154.400 157.372 44.381  1.00 184.36 ? 421 GLY A O   1 
ATOM   2972  N N   . TYR A 1 402 ? 153.933 155.160 44.301  1.00 191.06 ? 422 TYR A N   1 
ATOM   2973  C CA  . TYR A 1 402 ? 152.660 155.323 43.617  1.00 194.77 ? 422 TYR A CA  1 
ATOM   2974  C C   . TYR A 1 402 ? 151.625 155.929 44.562  1.00 191.31 ? 422 TYR A C   1 
ATOM   2975  O O   . TYR A 1 402 ? 151.435 155.441 45.674  1.00 190.36 ? 422 TYR A O   1 
ATOM   2976  C CB  . TYR A 1 402 ? 152.170 153.981 43.065  1.00 201.04 ? 422 TYR A CB  1 
ATOM   2977  C CG  . TYR A 1 402 ? 153.002 153.429 41.937  1.00 211.10 ? 422 TYR A CG  1 
ATOM   2978  C CD1 . TYR A 1 402 ? 152.787 153.822 40.624  1.00 216.03 ? 422 TYR A CD1 1 
ATOM   2979  C CD2 . TYR A 1 402 ? 154.025 152.529 42.184  1.00 217.70 ? 422 TYR A CD2 1 
ATOM   2980  C CE1 . TYR A 1 402 ? 153.553 153.319 39.584  1.00 220.71 ? 422 TYR A CE1 1 
ATOM   2981  C CE2 . TYR A 1 402 ? 154.801 152.016 41.156  1.00 221.74 ? 422 TYR A CE2 1 
ATOM   2982  C CZ  . TYR A 1 402 ? 154.565 152.413 39.851  1.00 223.20 ? 422 TYR A CZ  1 
ATOM   2983  O OH  . TYR A 1 402 ? 155.331 151.911 38.826  1.00 224.10 ? 422 TYR A OH  1 
ATOM   2984  N N   . ALA A 1 403 ? 150.959 156.992 44.094  1.00 187.37 ? 423 ALA A N   1 
ATOM   2985  C CA  . ALA A 1 403 ? 149.842 157.592 44.805  1.00 183.96 ? 423 ALA A CA  1 
ATOM   2986  C C   . ALA A 1 403 ? 148.543 156.976 44.292  1.00 177.37 ? 423 ALA A C   1 
ATOM   2987  O O   . ALA A 1 403 ? 147.780 157.623 43.577  1.00 175.22 ? 423 ALA A O   1 
ATOM   2988  C CB  . ALA A 1 403 ? 149.862 159.091 44.627  1.00 184.88 ? 423 ALA A CB  1 
ATOM   2989  N N   . GLY A 1 404 ? 148.319 155.710 44.665  1.00 170.91 ? 424 GLY A N   1 
ATOM   2990  C CA  . GLY A 1 404 ? 147.167 154.951 44.210  1.00 166.32 ? 424 GLY A CA  1 
ATOM   2991  C C   . GLY A 1 404 ? 147.368 153.452 44.416  1.00 161.55 ? 424 GLY A C   1 
ATOM   2992  O O   . GLY A 1 404 ? 148.369 153.028 44.989  1.00 158.99 ? 424 GLY A O   1 
ATOM   2993  N N   . LEU A 1 405 ? 146.405 152.660 43.926  1.00 159.38 ? 425 LEU A N   1 
ATOM   2994  C CA  . LEU A 1 405 ? 146.428 151.216 44.104  1.00 158.51 ? 425 LEU A CA  1 
ATOM   2995  C C   . LEU A 1 405 ? 147.493 150.601 43.200  1.00 157.93 ? 425 LEU A C   1 
ATOM   2996  O O   . LEU A 1 405 ? 147.264 150.395 42.010  1.00 157.32 ? 425 LEU A O   1 
ATOM   2997  C CB  . LEU A 1 405 ? 145.047 150.618 43.802  1.00 158.81 ? 425 LEU A CB  1 
ATOM   2998  C CG  . LEU A 1 405 ? 144.122 150.377 44.998  1.00 159.17 ? 425 LEU A CG  1 
ATOM   2999  C CD1 . LEU A 1 405 ? 143.038 149.378 44.628  1.00 160.74 ? 425 LEU A CD1 1 
ATOM   3000  C CD2 . LEU A 1 405 ? 144.892 149.887 46.216  1.00 156.92 ? 425 LEU A CD2 1 
ATOM   3001  N N   . CYS A 1 406 ? 148.657 150.324 43.793  1.00 157.62 ? 426 CYS A N   1 
ATOM   3002  C CA  . CYS A 1 406 ? 149.792 149.787 43.063  1.00 157.53 ? 426 CYS A CA  1 
ATOM   3003  C C   . CYS A 1 406 ? 149.565 148.301 42.782  1.00 155.90 ? 426 CYS A C   1 
ATOM   3004  O O   . CYS A 1 406 ? 148.616 147.693 43.284  1.00 153.66 ? 426 CYS A O   1 
ATOM   3005  C CB  . CYS A 1 406 ? 151.096 150.027 43.821  1.00 158.13 ? 426 CYS A CB  1 
ATOM   3006  S SG  . CYS A 1 406 ? 151.286 149.026 45.321  1.00 158.06 ? 426 CYS A SG  1 
ATOM   3007  N N   . ASP A 1 407 ? 150.456 147.734 41.960  1.00 155.51 ? 427 ASP A N   1 
ATOM   3008  C CA  . ASP A 1 407 ? 150.357 146.352 41.518  1.00 154.99 ? 427 ASP A CA  1 
ATOM   3009  C C   . ASP A 1 407 ? 150.482 145.400 42.708  1.00 149.05 ? 427 ASP A C   1 
ATOM   3010  O O   . ASP A 1 407 ? 149.841 144.355 42.731  1.00 146.68 ? 427 ASP A O   1 
ATOM   3011  C CB  . ASP A 1 407 ? 151.427 146.044 40.466  1.00 157.98 ? 427 ASP A CB  1 
ATOM   3012  C CG  . ASP A 1 407 ? 151.216 144.734 39.725  1.00 160.43 ? 427 ASP A CG  1 
ATOM   3013  O OD1 . ASP A 1 407 ? 150.124 144.147 39.862  1.00 160.42 ? 427 ASP A OD1 1 
ATOM   3014  O OD2 . ASP A 1 407 ? 152.151 144.309 39.020  1.00 162.09 ? 427 ASP A OD2 1 
ATOM   3015  N N   . ALA A 1 408 ? 151.316 145.769 43.689  1.00 144.48 ? 428 ALA A N   1 
ATOM   3016  C CA  . ALA A 1 408 ? 151.536 144.962 44.878  1.00 141.75 ? 428 ALA A CA  1 
ATOM   3017  C C   . ALA A 1 408 ? 150.321 144.983 45.808  1.00 138.36 ? 428 ALA A C   1 
ATOM   3018  O O   . ALA A 1 408 ? 150.309 144.248 46.795  1.00 137.14 ? 428 ALA A O   1 
ATOM   3019  C CB  . ALA A 1 408 ? 152.773 145.453 45.594  1.00 141.55 ? 428 ALA A CB  1 
ATOM   3020  N N   . MET A 1 409 ? 149.310 145.813 45.503  1.00 134.99 ? 429 MET A N   1 
ATOM   3021  C CA  . MET A 1 409 ? 148.209 146.024 46.428  1.00 131.22 ? 429 MET A CA  1 
ATOM   3022  C C   . MET A 1 409 ? 146.897 145.466 45.879  1.00 131.57 ? 429 MET A C   1 
ATOM   3023  O O   . MET A 1 409 ? 145.902 145.465 46.604  1.00 129.47 ? 429 MET A O   1 
ATOM   3024  C CB  . MET A 1 409 ? 148.014 147.512 46.732  1.00 128.13 ? 429 MET A CB  1 
ATOM   3025  C CG  . MET A 1 409 ? 147.187 147.754 47.978  1.00 124.72 ? 429 MET A CG  1 
ATOM   3026  S SD  . MET A 1 409 ? 148.213 147.673 49.458  1.00 119.26 ? 429 MET A SD  1 
ATOM   3027  C CE  . MET A 1 409 ? 148.932 149.311 49.393  1.00 116.68 ? 429 MET A CE  1 
ATOM   3028  N N   . LYS A 1 410 ? 146.877 144.996 44.622  1.00 133.31 ? 430 LYS A N   1 
ATOM   3029  C CA  . LYS A 1 410 ? 145.624 144.560 44.014  1.00 135.31 ? 430 LYS A CA  1 
ATOM   3030  C C   . LYS A 1 410 ? 144.985 143.460 44.870  1.00 130.96 ? 430 LYS A C   1 
ATOM   3031  O O   . LYS A 1 410 ? 143.806 143.556 45.204  1.00 131.49 ? 430 LYS A O   1 
ATOM   3032  C CB  . LYS A 1 410 ? 145.804 144.122 42.553  1.00 139.91 ? 430 LYS A CB  1 
ATOM   3033  C CG  . LYS A 1 410 ? 145.384 145.139 41.498  1.00 144.25 ? 430 LYS A CG  1 
ATOM   3034  C CD  . LYS A 1 410 ? 146.142 146.445 41.555  1.00 147.51 ? 430 LYS A CD  1 
ATOM   3035  C CE  . LYS A 1 410 ? 145.843 147.354 40.382  1.00 149.71 ? 430 LYS A CE  1 
ATOM   3036  N NZ  . LYS A 1 410 ? 146.811 148.473 40.292  1.00 150.57 ? 430 LYS A NZ  1 
ATOM   3037  N N   . PRO A 1 411 ? 145.712 142.384 45.255  1.00 123.82 ? 431 PRO A N   1 
ATOM   3038  C CA  . PRO A 1 411 ? 145.188 141.411 46.210  1.00 118.87 ? 431 PRO A CA  1 
ATOM   3039  C C   . PRO A 1 411 ? 145.573 141.820 47.630  1.00 112.85 ? 431 PRO A C   1 
ATOM   3040  O O   . PRO A 1 411 ? 146.598 141.383 48.150  1.00 113.84 ? 431 PRO A O   1 
ATOM   3041  C CB  . PRO A 1 411 ? 145.861 140.112 45.744  1.00 120.62 ? 431 PRO A CB  1 
ATOM   3042  C CG  . PRO A 1 411 ? 147.207 140.555 45.181  1.00 122.51 ? 431 PRO A CG  1 
ATOM   3043  C CD  . PRO A 1 411 ? 147.058 142.015 44.796  1.00 123.07 ? 431 PRO A CD  1 
ATOM   3044  N N   . ILE A 1 412 ? 144.745 142.676 48.243  1.00 105.22 ? 432 ILE A N   1 
ATOM   3045  C CA  . ILE A 1 412 ? 145.056 143.226 49.554  1.00 99.76  ? 432 ILE A CA  1 
ATOM   3046  C C   . ILE A 1 412 ? 145.184 142.072 50.547  1.00 95.97  ? 432 ILE A C   1 
ATOM   3047  O O   . ILE A 1 412 ? 144.244 141.302 50.732  1.00 94.46  ? 432 ILE A O   1 
ATOM   3048  C CB  . ILE A 1 412 ? 144.011 144.265 50.018  1.00 97.68  ? 432 ILE A CB  1 
ATOM   3049  C CG1 . ILE A 1 412 ? 143.823 145.395 49.002  1.00 97.91  ? 432 ILE A CG1 1 
ATOM   3050  C CG2 . ILE A 1 412 ? 144.370 144.808 51.396  1.00 96.86  ? 432 ILE A CG2 1 
ATOM   3051  C CD1 . ILE A 1 412 ? 142.704 145.166 48.011  1.00 98.37  ? 432 ILE A CD1 1 
ATOM   3052  N N   . ASP A 1 413 ? 146.366 141.963 51.164  1.00 92.85  ? 433 ASP A N   1 
ATOM   3053  C CA  . ASP A 1 413 ? 146.676 140.884 52.087  1.00 91.04  ? 433 ASP A CA  1 
ATOM   3054  C C   . ASP A 1 413 ? 146.135 141.236 53.469  1.00 86.09  ? 433 ASP A C   1 
ATOM   3055  O O   . ASP A 1 413 ? 146.504 142.260 54.035  1.00 85.55  ? 433 ASP A O   1 
ATOM   3056  C CB  . ASP A 1 413 ? 148.185 140.619 52.113  1.00 94.78  ? 433 ASP A CB  1 
ATOM   3057  C CG  . ASP A 1 413 ? 148.656 139.764 53.278  1.00 97.42  ? 433 ASP A CG  1 
ATOM   3058  O OD1 . ASP A 1 413 ? 148.694 140.287 54.409  1.00 96.94  ? 433 ASP A OD1 1 
ATOM   3059  O OD2 . ASP A 1 413 ? 148.987 138.585 53.043  1.00 98.39  ? 433 ASP A OD2 1 
ATOM   3060  N N   . GLY A 1 414 ? 145.277 140.363 54.005  1.00 83.06  ? 434 GLY A N   1 
ATOM   3061  C CA  . GLY A 1 414 ? 144.643 140.589 55.293  1.00 81.81  ? 434 GLY A CA  1 
ATOM   3062  C C   . GLY A 1 414 ? 145.645 140.589 56.447  1.00 81.88  ? 434 GLY A C   1 
ATOM   3063  O O   . GLY A 1 414 ? 145.430 141.252 57.460  1.00 80.65  ? 434 GLY A O   1 
ATOM   3064  N N   . ARG A 1 415 ? 146.731 139.823 56.293  1.00 84.50  ? 435 ARG A N   1 
ATOM   3065  C CA  . ARG A 1 415 ? 147.716 139.677 57.353  1.00 88.05  ? 435 ARG A CA  1 
ATOM   3066  C C   . ARG A 1 415 ? 148.496 140.981 57.510  1.00 85.48  ? 435 ARG A C   1 
ATOM   3067  O O   . ARG A 1 415 ? 148.681 141.460 58.625  1.00 85.10  ? 435 ARG A O   1 
ATOM   3068  C CB  . ARG A 1 415 ? 148.625 138.480 57.062  1.00 94.60  ? 435 ARG A CB  1 
ATOM   3069  C CG  . ARG A 1 415 ? 149.649 138.182 58.149  1.00 101.35 ? 435 ARG A CG  1 
ATOM   3070  C CD  . ARG A 1 415 ? 150.655 137.125 57.722  1.00 106.74 ? 435 ARG A CD  1 
ATOM   3071  N NE  . ARG A 1 415 ? 151.251 137.393 56.415  1.00 112.23 ? 435 ARG A NE  1 
ATOM   3072  C CZ  . ARG A 1 415 ? 152.039 138.427 56.123  1.00 117.46 ? 435 ARG A CZ  1 
ATOM   3073  N NH1 . ARG A 1 415 ? 152.447 139.252 57.072  1.00 118.81 ? 435 ARG A NH1 1 
ATOM   3074  N NH2 . ARG A 1 415 ? 152.430 138.626 54.874  1.00 117.66 ? 435 ARG A NH2 1 
ATOM   3075  N N   . LYS A 1 416 ? 148.947 141.550 56.388  1.00 83.06  ? 436 LYS A N   1 
ATOM   3076  C CA  . LYS A 1 416 ? 149.671 142.811 56.402  1.00 82.10  ? 436 LYS A CA  1 
ATOM   3077  C C   . LYS A 1 416 ? 148.762 143.937 56.894  1.00 76.63  ? 436 LYS A C   1 
ATOM   3078  O O   . LYS A 1 416 ? 149.211 144.832 57.609  1.00 75.43  ? 436 LYS A O   1 
ATOM   3079  C CB  . LYS A 1 416 ? 150.247 143.110 55.016  1.00 85.49  ? 436 LYS A CB  1 
ATOM   3080  C CG  . LYS A 1 416 ? 151.512 142.329 54.680  1.00 88.65  ? 436 LYS A CG  1 
ATOM   3081  C CD  . LYS A 1 416 ? 152.271 142.889 53.492  1.00 91.16  ? 436 LYS A CD  1 
ATOM   3082  C CE  . LYS A 1 416 ? 151.585 142.639 52.166  1.00 92.40  ? 436 LYS A CE  1 
ATOM   3083  N NZ  . LYS A 1 416 ? 151.583 141.198 51.824  1.00 92.07  ? 436 LYS A NZ  1 
ATOM   3084  N N   . LEU A 1 417 ? 147.482 143.890 56.504  1.00 70.81  ? 437 LEU A N   1 
ATOM   3085  C CA  . LEU A 1 417 ? 146.516 144.881 56.953  1.00 66.26  ? 437 LEU A CA  1 
ATOM   3086  C C   . LEU A 1 417 ? 146.339 144.770 58.464  1.00 64.01  ? 437 LEU A C   1 
ATOM   3087  O O   . LEU A 1 417 ? 146.259 145.784 59.140  1.00 64.43  ? 437 LEU A O   1 
ATOM   3088  C CB  . LEU A 1 417 ? 145.182 144.699 56.219  1.00 64.16  ? 437 LEU A CB  1 
ATOM   3089  C CG  . LEU A 1 417 ? 144.051 145.634 56.652  1.00 62.60  ? 437 LEU A CG  1 
ATOM   3090  C CD1 . LEU A 1 417 ? 144.437 147.098 56.462  1.00 62.14  ? 437 LEU A CD1 1 
ATOM   3091  C CD2 . LEU A 1 417 ? 142.768 145.311 55.899  1.00 62.41  ? 437 LEU A CD2 1 
ATOM   3092  N N   . LEU A 1 418 ? 146.285 143.544 58.986  1.00 63.14  ? 438 LEU A N   1 
ATOM   3093  C CA  . LEU A 1 418 ? 146.184 143.332 60.420  1.00 63.70  ? 438 LEU A CA  1 
ATOM   3094  C C   . LEU A 1 418 ? 147.388 143.949 61.132  1.00 66.79  ? 438 LEU A C   1 
ATOM   3095  O O   . LEU A 1 418 ? 147.235 144.586 62.171  1.00 68.33  ? 438 LEU A O   1 
ATOM   3096  C CB  . LEU A 1 418 ? 146.097 141.831 60.710  1.00 62.52  ? 438 LEU A CB  1 
ATOM   3097  C CG  . LEU A 1 418 ? 145.985 141.497 62.193  1.00 61.59  ? 438 LEU A CG  1 
ATOM   3098  C CD1 . LEU A 1 418 ? 144.584 141.806 62.674  1.00 60.54  ? 438 LEU A CD1 1 
ATOM   3099  C CD2 . LEU A 1 418 ? 146.335 140.043 62.474  1.00 62.13  ? 438 LEU A CD2 1 
ATOM   3100  N N   . GLU A 1 419 ? 148.585 143.746 60.571  1.00 69.58  ? 439 GLU A N   1 
ATOM   3101  C CA  . GLU A 1 419 ? 149.807 144.268 61.165  1.00 72.43  ? 439 GLU A CA  1 
ATOM   3102  C C   . GLU A 1 419 ? 149.762 145.795 61.214  1.00 69.91  ? 439 GLU A C   1 
ATOM   3103  O O   . GLU A 1 419 ? 149.987 146.389 62.268  1.00 70.59  ? 439 GLU A O   1 
ATOM   3104  C CB  . GLU A 1 419 ? 151.042 143.784 60.401  1.00 76.94  ? 439 GLU A CB  1 
ATOM   3105  C CG  . GLU A 1 419 ? 151.367 142.321 60.640  1.00 81.43  ? 439 GLU A CG  1 
ATOM   3106  C CD  . GLU A 1 419 ? 151.174 141.867 62.077  1.00 84.59  ? 439 GLU A CD  1 
ATOM   3107  O OE1 . GLU A 1 419 ? 151.879 142.394 62.962  1.00 85.85  ? 439 GLU A OE1 1 
ATOM   3108  O OE2 . GLU A 1 419 ? 150.300 141.008 62.308  1.00 85.39  ? 439 GLU A OE2 1 
ATOM   3109  N N   . SER A 1 420 ? 149.443 146.416 60.075  1.00 66.23  ? 440 SER A N   1 
ATOM   3110  C CA  . SER A 1 420 ? 149.381 147.867 59.988  1.00 64.24  ? 440 SER A CA  1 
ATOM   3111  C C   . SER A 1 420 ? 148.320 148.419 60.940  1.00 62.22  ? 440 SER A C   1 
ATOM   3112  O O   . SER A 1 420 ? 148.580 149.384 61.656  1.00 62.73  ? 440 SER A O   1 
ATOM   3113  C CB  . SER A 1 420 ? 149.156 148.315 58.573  1.00 64.20  ? 440 SER A CB  1 
ATOM   3114  O OG  . SER A 1 420 ? 147.919 147.833 58.079  1.00 64.90  ? 440 SER A OG  1 
ATOM   3115  N N   . LEU A 1 421 ? 147.136 147.793 60.952  1.00 60.71  ? 441 LEU A N   1 
ATOM   3116  C CA  . LEU A 1 421 ? 146.065 148.186 61.856  1.00 60.06  ? 441 LEU A CA  1 
ATOM   3117  C C   . LEU A 1 421 ? 146.538 148.097 63.301  1.00 63.02  ? 441 LEU A C   1 
ATOM   3118  O O   . LEU A 1 421 ? 146.106 148.888 64.130  1.00 65.41  ? 441 LEU A O   1 
ATOM   3119  C CB  . LEU A 1 421 ? 144.837 147.285 61.667  1.00 57.32  ? 441 LEU A CB  1 
ATOM   3120  C CG  . LEU A 1 421 ? 143.987 147.484 60.412  1.00 55.00  ? 441 LEU A CG  1 
ATOM   3121  C CD1 . LEU A 1 421 ? 142.642 146.799 60.562  1.00 53.39  ? 441 LEU A CD1 1 
ATOM   3122  C CD2 . LEU A 1 421 ? 143.771 148.943 60.094  1.00 54.94  ? 441 LEU A CD2 1 
ATOM   3123  N N   . MET A 1 422 ? 147.401 147.124 63.607  1.00 65.31  ? 442 MET A N   1 
ATOM   3124  C CA  . MET A 1 422 ? 147.860 146.939 64.973  1.00 69.11  ? 442 MET A CA  1 
ATOM   3125  C C   . MET A 1 422 ? 148.790 148.084 65.377  1.00 71.60  ? 442 MET A C   1 
ATOM   3126  O O   . MET A 1 422 ? 148.731 148.558 66.508  1.00 71.43  ? 442 MET A O   1 
ATOM   3127  C CB  . MET A 1 422 ? 148.577 145.596 65.142  1.00 72.22  ? 442 MET A CB  1 
ATOM   3128  C CG  . MET A 1 422 ? 147.641 144.444 65.403  1.00 75.56  ? 442 MET A CG  1 
ATOM   3129  S SD  . MET A 1 422 ? 147.193 144.274 67.142  1.00 81.50  ? 442 MET A SD  1 
ATOM   3130  C CE  . MET A 1 422 ? 147.599 142.543 67.360  1.00 83.18  ? 442 MET A CE  1 
ATOM   3131  N N   . LYS A 1 423 ? 149.624 148.554 64.444  1.00 74.79  ? 443 LYS A N   1 
ATOM   3132  C CA  . LYS A 1 423 ? 150.635 149.549 64.765  1.00 77.73  ? 443 LYS A CA  1 
ATOM   3133  C C   . LYS A 1 423 ? 150.173 150.963 64.406  1.00 76.39  ? 443 LYS A C   1 
ATOM   3134  O O   . LYS A 1 423 ? 150.934 151.913 64.588  1.00 77.36  ? 443 LYS A O   1 
ATOM   3135  C CB  . LYS A 1 423 ? 151.959 149.202 64.073  1.00 80.26  ? 443 LYS A CB  1 
ATOM   3136  C CG  . LYS A 1 423 ? 151.927 149.071 62.555  1.00 83.17  ? 443 LYS A CG  1 
ATOM   3137  C CD  . LYS A 1 423 ? 153.080 148.222 62.051  1.00 85.98  ? 443 LYS A CD  1 
ATOM   3138  C CE  . LYS A 1 423 ? 153.118 148.068 60.546  1.00 87.37  ? 443 LYS A CE  1 
ATOM   3139  N NZ  . LYS A 1 423 ? 153.245 149.381 59.870  1.00 87.70  ? 443 LYS A NZ  1 
ATOM   3140  N N   . THR A 1 424 ? 148.937 151.121 63.909  1.00 74.12  ? 444 THR A N   1 
ATOM   3141  C CA  . THR A 1 424 ? 148.441 152.435 63.517  1.00 73.01  ? 444 THR A CA  1 
ATOM   3142  C C   . THR A 1 424 ? 148.174 153.311 64.740  1.00 72.96  ? 444 THR A C   1 
ATOM   3143  O O   . THR A 1 424 ? 147.825 152.815 65.812  1.00 74.08  ? 444 THR A O   1 
ATOM   3144  C CB  . THR A 1 424 ? 147.151 152.351 62.693  1.00 72.46  ? 444 THR A CB  1 
ATOM   3145  O OG1 . THR A 1 424 ? 146.348 151.293 63.215  1.00 72.54  ? 444 THR A OG1 1 
ATOM   3146  C CG2 . THR A 1 424 ? 147.395 152.116 61.222  1.00 71.90  ? 444 THR A CG2 1 
ATOM   3147  N N   . ALA A 1 425 ? 148.351 154.624 64.546  1.00 72.17  ? 445 ALA A N   1 
ATOM   3148  C CA  . ALA A 1 425 ? 147.945 155.636 65.506  1.00 72.39  ? 445 ALA A CA  1 
ATOM   3149  C C   . ALA A 1 425 ? 147.604 156.920 64.754  1.00 73.33  ? 445 ALA A C   1 
ATOM   3150  O O   . ALA A 1 425 ? 148.185 157.191 63.706  1.00 74.13  ? 445 ALA A O   1 
ATOM   3151  C CB  . ALA A 1 425 ? 149.044 155.865 66.516  1.00 72.64  ? 445 ALA A CB  1 
ATOM   3152  N N   . PHE A 1 426 ? 146.650 157.690 65.290  1.00 73.91  ? 446 PHE A N   1 
ATOM   3153  C CA  . PHE A 1 426 ? 146.261 158.971 64.720  1.00 75.00  ? 446 PHE A CA  1 
ATOM   3154  C C   . PHE A 1 426 ? 145.389 159.717 65.727  1.00 78.42  ? 446 PHE A C   1 
ATOM   3155  O O   . PHE A 1 426 ? 145.211 159.262 66.858  1.00 78.65  ? 446 PHE A O   1 
ATOM   3156  C CB  . PHE A 1 426 ? 145.534 158.782 63.383  1.00 72.47  ? 446 PHE A CB  1 
ATOM   3157  C CG  . PHE A 1 426 ? 144.285 157.944 63.471  1.00 70.74  ? 446 PHE A CG  1 
ATOM   3158  C CD1 . PHE A 1 426 ? 143.086 158.480 63.912  1.00 70.23  ? 446 PHE A CD1 1 
ATOM   3159  C CD2 . PHE A 1 426 ? 144.326 156.597 63.149  1.00 69.44  ? 446 PHE A CD2 1 
ATOM   3160  C CE1 . PHE A 1 426 ? 141.944 157.696 63.990  1.00 69.20  ? 446 PHE A CE1 1 
ATOM   3161  C CE2 . PHE A 1 426 ? 143.188 155.813 63.243  1.00 68.10  ? 446 PHE A CE2 1 
ATOM   3162  C CZ  . PHE A 1 426 ? 142.003 156.360 63.674  1.00 67.33  ? 446 PHE A CZ  1 
ATOM   3163  N N   . THR A 1 427 ? 144.857 160.869 65.303  1.00 81.07  ? 447 THR A N   1 
ATOM   3164  C CA  . THR A 1 427 ? 143.989 161.679 66.138  1.00 83.20  ? 447 THR A CA  1 
ATOM   3165  C C   . THR A 1 427 ? 142.537 161.439 65.735  1.00 84.02  ? 447 THR A C   1 
ATOM   3166  O O   . THR A 1 427 ? 142.177 161.605 64.571  1.00 83.84  ? 447 THR A O   1 
ATOM   3167  C CB  . THR A 1 427 ? 144.372 163.158 66.034  1.00 84.87  ? 447 THR A CB  1 
ATOM   3168  O OG1 . THR A 1 427 ? 144.124 163.594 64.696  1.00 84.95  ? 447 THR A OG1 1 
ATOM   3169  C CG2 . THR A 1 427 ? 145.818 163.412 66.400  1.00 85.16  ? 447 THR A CG2 1 
ATOM   3170  N N   . GLY A 1 428 ? 141.718 161.038 66.716  1.00 85.18  ? 448 GLY A N   1 
ATOM   3171  C CA  . GLY A 1 428 ? 140.321 160.710 66.485  1.00 84.70  ? 448 GLY A CA  1 
ATOM   3172  C C   . GLY A 1 428 ? 139.465 161.963 66.330  1.00 84.51  ? 448 GLY A C   1 
ATOM   3173  O O   . GLY A 1 428 ? 139.961 163.084 66.444  1.00 86.02  ? 448 GLY A O   1 
ATOM   3174  N N   . VAL A 1 429 ? 138.174 161.749 66.068  1.00 83.13  ? 449 VAL A N   1 
ATOM   3175  C CA  . VAL A 1 429 ? 137.223 162.836 65.903  1.00 83.31  ? 449 VAL A CA  1 
ATOM   3176  C C   . VAL A 1 429 ? 137.085 163.614 67.212  1.00 87.32  ? 449 VAL A C   1 
ATOM   3177  O O   . VAL A 1 429 ? 136.910 164.832 67.190  1.00 87.12  ? 449 VAL A O   1 
ATOM   3178  C CB  . VAL A 1 429 ? 135.864 162.313 65.403  1.00 79.09  ? 449 VAL A CB  1 
ATOM   3179  C CG1 . VAL A 1 429 ? 135.927 161.951 63.930  1.00 76.62  ? 449 VAL A CG1 1 
ATOM   3180  C CG2 . VAL A 1 429 ? 135.356 161.136 66.222  1.00 78.35  ? 449 VAL A CG2 1 
ATOM   3181  N N   . SER A 1 430 ? 137.175 162.902 68.344  1.00 91.07  ? 450 SER A N   1 
ATOM   3182  C CA  . SER A 1 430 ? 137.089 163.521 69.657  1.00 95.05  ? 450 SER A CA  1 
ATOM   3183  C C   . SER A 1 430 ? 138.228 164.521 69.856  1.00 96.77  ? 450 SER A C   1 
ATOM   3184  O O   . SER A 1 430 ? 138.013 165.603 70.399  1.00 97.73  ? 450 SER A O   1 
ATOM   3185  C CB  . SER A 1 430 ? 137.076 162.477 70.744  1.00 96.33  ? 450 SER A CB  1 
ATOM   3186  O OG  . SER A 1 430 ? 138.220 161.638 70.663  1.00 96.95  ? 450 SER A OG  1 
ATOM   3187  N N   . GLY A 1 431 ? 139.433 164.149 69.408  1.00 97.48  ? 451 GLY A N   1 
ATOM   3188  C CA  . GLY A 1 431 ? 140.593 165.021 69.488  1.00 98.66  ? 451 GLY A CA  1 
ATOM   3189  C C   . GLY A 1 431 ? 141.818 164.283 70.019  1.00 99.91  ? 451 GLY A C   1 
ATOM   3190  O O   . GLY A 1 431 ? 142.937 164.541 69.578  1.00 100.85 ? 451 GLY A O   1 
ATOM   3191  N N   . ASP A 1 432 ? 141.590 163.375 70.976  1.00 99.98  ? 452 ASP A N   1 
ATOM   3192  C CA  . ASP A 1 432 ? 142.664 162.607 71.584  1.00 99.71  ? 452 ASP A CA  1 
ATOM   3193  C C   . ASP A 1 432 ? 143.235 161.625 70.565  1.00 96.05  ? 452 ASP A C   1 
ATOM   3194  O O   . ASP A 1 432 ? 142.586 161.297 69.576  1.00 94.81  ? 452 ASP A O   1 
ATOM   3195  C CB  . ASP A 1 432 ? 142.189 161.881 72.847  1.00 102.16 ? 452 ASP A CB  1 
ATOM   3196  C CG  . ASP A 1 432 ? 141.008 160.947 72.634  1.00 104.04 ? 452 ASP A CG  1 
ATOM   3197  O OD1 . ASP A 1 432 ? 140.705 160.615 71.477  1.00 104.53 ? 452 ASP A OD1 1 
ATOM   3198  O OD2 . ASP A 1 432 ? 140.361 160.598 73.634  1.00 104.83 ? 452 ASP A OD2 1 
ATOM   3199  N N   . THR A 1 433 ? 144.454 161.145 70.831  1.00 93.62  ? 453 THR A N   1 
ATOM   3200  C CA  . THR A 1 433 ? 145.069 160.119 70.004  1.00 90.94  ? 453 THR A CA  1 
ATOM   3201  C C   . THR A 1 433 ? 144.570 158.749 70.455  1.00 86.08  ? 453 THR A C   1 
ATOM   3202  O O   . THR A 1 433 ? 144.324 158.530 71.641  1.00 84.86  ? 453 THR A O   1 
ATOM   3203  C CB  . THR A 1 433 ? 146.601 160.194 70.057  1.00 93.12  ? 453 THR A CB  1 
ATOM   3204  O OG1 . THR A 1 433 ? 147.126 159.377 69.010  1.00 92.40  ? 453 THR A OG1 1 
ATOM   3205  C CG2 . THR A 1 433 ? 147.177 159.747 71.384  1.00 94.57  ? 453 THR A CG2 1 
ATOM   3206  N N   . ILE A 1 434 ? 144.436 157.833 69.492  1.00 82.09  ? 454 ILE A N   1 
ATOM   3207  C CA  . ILE A 1 434 ? 144.005 156.472 69.765  1.00 79.08  ? 454 ILE A CA  1 
ATOM   3208  C C   . ILE A 1 434 ? 145.037 155.517 69.179  1.00 76.34  ? 454 ILE A C   1 
ATOM   3209  O O   . ILE A 1 434 ? 145.541 155.739 68.083  1.00 76.48  ? 454 ILE A O   1 
ATOM   3210  C CB  . ILE A 1 434 ? 142.592 156.218 69.207  1.00 77.88  ? 454 ILE A CB  1 
ATOM   3211  C CG1 . ILE A 1 434 ? 142.520 156.511 67.707  1.00 76.11  ? 454 ILE A CG1 1 
ATOM   3212  C CG2 . ILE A 1 434 ? 141.576 157.023 70.005  1.00 78.89  ? 454 ILE A CG2 1 
ATOM   3213  C CD1 . ILE A 1 434 ? 141.173 156.221 67.082  1.00 75.63  ? 454 ILE A CD1 1 
ATOM   3214  N N   . LEU A 1 435 ? 145.314 154.442 69.924  1.00 73.14  ? 455 LEU A N   1 
ATOM   3215  C CA  . LEU A 1 435 ? 146.303 153.439 69.559  1.00 70.44  ? 455 LEU A CA  1 
ATOM   3216  C C   . LEU A 1 435 ? 145.790 152.066 69.984  1.00 66.42  ? 455 LEU A C   1 
ATOM   3217  O O   . LEU A 1 435 ? 144.842 151.978 70.757  1.00 67.20  ? 455 LEU A O   1 
ATOM   3218  C CB  . LEU A 1 435 ? 147.627 153.774 70.254  1.00 72.08  ? 455 LEU A CB  1 
ATOM   3219  C CG  . LEU A 1 435 ? 147.584 153.847 71.783  1.00 74.53  ? 455 LEU A CG  1 
ATOM   3220  C CD1 . LEU A 1 435 ? 148.002 152.531 72.426  1.00 74.10  ? 455 LEU A CD1 1 
ATOM   3221  C CD2 . LEU A 1 435 ? 148.455 154.985 72.296  1.00 75.96  ? 455 LEU A CD2 1 
ATOM   3222  N N   . PHE A 1 436 ? 146.429 151.002 69.489  1.00 62.00  ? 456 PHE A N   1 
ATOM   3223  C CA  . PHE A 1 436 ? 146.052 149.651 69.871  1.00 59.40  ? 456 PHE A CA  1 
ATOM   3224  C C   . PHE A 1 436 ? 147.174 148.992 70.667  1.00 59.90  ? 456 PHE A C   1 
ATOM   3225  O O   . PHE A 1 436 ? 148.332 149.030 70.257  1.00 61.51  ? 456 PHE A O   1 
ATOM   3226  C CB  . PHE A 1 436 ? 145.716 148.818 68.635  1.00 57.59  ? 456 PHE A CB  1 
ATOM   3227  C CG  . PHE A 1 436 ? 144.487 149.278 67.896  1.00 55.36  ? 456 PHE A CG  1 
ATOM   3228  C CD1 . PHE A 1 436 ? 143.250 149.284 68.516  1.00 54.73  ? 456 PHE A CD1 1 
ATOM   3229  C CD2 . PHE A 1 436 ? 144.566 149.700 66.580  1.00 54.32  ? 456 PHE A CD2 1 
ATOM   3230  C CE1 . PHE A 1 436 ? 142.120 149.705 67.836  1.00 54.37  ? 456 PHE A CE1 1 
ATOM   3231  C CE2 . PHE A 1 436 ? 143.433 150.116 65.900  1.00 54.23  ? 456 PHE A CE2 1 
ATOM   3232  C CZ  . PHE A 1 436 ? 142.213 150.115 66.530  1.00 54.23  ? 456 PHE A CZ  1 
ATOM   3233  N N   . ASP A 1 437 ? 146.814 148.377 71.801  1.00 59.77  ? 457 ASP A N   1 
ATOM   3234  C CA  . ASP A 1 437 ? 147.793 147.707 72.642  1.00 61.47  ? 457 ASP A CA  1 
ATOM   3235  C C   . ASP A 1 437 ? 148.102 146.341 72.032  1.00 61.96  ? 457 ASP A C   1 
ATOM   3236  O O   . ASP A 1 437 ? 147.759 146.088 70.882  1.00 61.76  ? 457 ASP A O   1 
ATOM   3237  C CB  . ASP A 1 437 ? 147.319 147.674 74.097  1.00 62.94  ? 457 ASP A CB  1 
ATOM   3238  C CG  . ASP A 1 437 ? 146.215 146.677 74.399  1.00 63.95  ? 457 ASP A CG  1 
ATOM   3239  O OD1 . ASP A 1 437 ? 145.980 145.791 73.564  1.00 64.24  ? 457 ASP A OD1 1 
ATOM   3240  O OD2 . ASP A 1 437 ? 145.596 146.797 75.472  1.00 64.72  ? 457 ASP A OD2 1 
ATOM   3241  N N   . GLU A 1 438 ? 148.777 145.477 72.798  1.00 62.87  ? 458 GLU A N   1 
ATOM   3242  C CA  . GLU A 1 438 ? 149.194 144.177 72.293  1.00 63.80  ? 458 GLU A CA  1 
ATOM   3243  C C   . GLU A 1 438 ? 147.982 143.269 72.083  1.00 61.03  ? 458 GLU A C   1 
ATOM   3244  O O   . GLU A 1 438 ? 148.025 142.379 71.239  1.00 60.90  ? 458 GLU A O   1 
ATOM   3245  C CB  . GLU A 1 438 ? 150.221 143.511 73.216  1.00 66.50  ? 458 GLU A CB  1 
ATOM   3246  C CG  . GLU A 1 438 ? 149.682 143.094 74.577  1.00 68.12  ? 458 GLU A CG  1 
ATOM   3247  C CD  . GLU A 1 438 ? 149.483 144.220 75.577  1.00 69.34  ? 458 GLU A CD  1 
ATOM   3248  O OE1 . GLU A 1 438 ? 149.751 145.384 75.217  1.00 68.96  ? 458 GLU A OE1 1 
ATOM   3249  O OE2 . GLU A 1 438 ? 149.070 143.930 76.718  1.00 70.61  ? 458 GLU A OE2 1 
ATOM   3250  N N   . ASN A 1 439 ? 146.910 143.490 72.854  1.00 58.48  ? 459 ASN A N   1 
ATOM   3251  C CA  . ASN A 1 439 ? 145.711 142.671 72.763  1.00 57.17  ? 459 ASN A CA  1 
ATOM   3252  C C   . ASN A 1 439 ? 144.660 143.316 71.858  1.00 55.46  ? 459 ASN A C   1 
ATOM   3253  O O   . ASN A 1 439 ? 143.514 142.879 71.844  1.00 56.38  ? 459 ASN A O   1 
ATOM   3254  C CB  . ASN A 1 439 ? 145.108 142.410 74.146  1.00 59.29  ? 459 ASN A CB  1 
ATOM   3255  C CG  . ASN A 1 439 ? 146.090 141.755 75.092  1.00 62.42  ? 459 ASN A CG  1 
ATOM   3256  O OD1 . ASN A 1 439 ? 146.630 140.691 74.795  1.00 63.14  ? 459 ASN A OD1 1 
ATOM   3257  N ND2 . ASN A 1 439 ? 146.339 142.388 76.228  1.00 64.08  ? 459 ASN A ND2 1 
ATOM   3258  N N   . GLY A 1 440 ? 145.027 144.383 71.139  1.00 52.84  ? 460 GLY A N   1 
ATOM   3259  C CA  . GLY A 1 440 ? 144.139 144.990 70.158  1.00 49.96  ? 460 GLY A CA  1 
ATOM   3260  C C   . GLY A 1 440 ? 143.095 145.923 70.773  1.00 47.82  ? 460 GLY A C   1 
ATOM   3261  O O   . GLY A 1 440 ? 142.234 146.431 70.061  1.00 47.91  ? 460 GLY A O   1 
ATOM   3262  N N   . ASP A 1 441 ? 143.185 146.175 72.084  1.00 46.21  ? 461 ASP A N   1 
ATOM   3263  C CA  . ASP A 1 441 ? 142.251 147.069 72.752  1.00 45.67  ? 461 ASP A CA  1 
ATOM   3264  C C   . ASP A 1 441 ? 142.702 148.509 72.520  1.00 45.10  ? 461 ASP A C   1 
ATOM   3265  O O   . ASP A 1 441 ? 143.623 148.763 71.750  1.00 46.41  ? 461 ASP A O   1 
ATOM   3266  C CB  . ASP A 1 441 ? 142.144 146.748 74.245  1.00 46.49  ? 461 ASP A CB  1 
ATOM   3267  C CG  . ASP A 1 441 ? 141.970 145.269 74.533  1.00 47.79  ? 461 ASP A CG  1 
ATOM   3268  O OD1 . ASP A 1 441 ? 141.460 144.567 73.639  1.00 47.67  ? 461 ASP A OD1 1 
ATOM   3269  O OD2 . ASP A 1 441 ? 142.428 144.820 75.606  1.00 49.02  ? 461 ASP A OD2 1 
ATOM   3270  N N   . SER A 1 442 ? 142.031 149.453 73.186  1.00 44.09  ? 462 SER A N   1 
ATOM   3271  C CA  . SER A 1 442 ? 142.405 150.853 73.124  1.00 43.53  ? 462 SER A CA  1 
ATOM   3272  C C   . SER A 1 442 ? 142.150 151.489 74.486  1.00 44.14  ? 462 SER A C   1 
ATOM   3273  O O   . SER A 1 442 ? 141.225 151.085 75.186  1.00 44.65  ? 462 SER A O   1 
ATOM   3274  C CB  . SER A 1 442 ? 141.652 151.554 72.024  1.00 43.13  ? 462 SER A CB  1 
ATOM   3275  O OG  . SER A 1 442 ? 142.007 152.929 71.951  1.00 43.32  ? 462 SER A OG  1 
ATOM   3276  N N   . PRO A 1 443 ? 142.963 152.479 74.920  1.00 45.06  ? 463 PRO A N   1 
ATOM   3277  C CA  . PRO A 1 443 ? 142.743 153.130 76.209  1.00 45.75  ? 463 PRO A CA  1 
ATOM   3278  C C   . PRO A 1 443 ? 141.449 153.940 76.195  1.00 45.56  ? 463 PRO A C   1 
ATOM   3279  O O   . PRO A 1 443 ? 141.070 154.498 75.166  1.00 45.71  ? 463 PRO A O   1 
ATOM   3280  C CB  . PRO A 1 443 ? 143.966 154.043 76.405  1.00 46.34  ? 463 PRO A CB  1 
ATOM   3281  C CG  . PRO A 1 443 ? 144.957 153.624 75.333  1.00 46.21  ? 463 PRO A CG  1 
ATOM   3282  C CD  . PRO A 1 443 ? 144.129 153.027 74.214  1.00 45.47  ? 463 PRO A CD  1 
ATOM   3283  N N   . GLY A 1 444 ? 140.772 153.977 77.346  1.00 45.10  ? 464 GLY A N   1 
ATOM   3284  C CA  . GLY A 1 444 ? 139.540 154.729 77.494  1.00 45.13  ? 464 GLY A CA  1 
ATOM   3285  C C   . GLY A 1 444 ? 139.256 155.048 78.958  1.00 45.27  ? 464 GLY A C   1 
ATOM   3286  O O   . GLY A 1 444 ? 139.843 154.440 79.854  1.00 45.94  ? 464 GLY A O   1 
ATOM   3287  N N   . ARG A 1 445 ? 138.344 156.001 79.177  1.00 44.39  ? 465 ARG A N   1 
ATOM   3288  C CA  . ARG A 1 445 ? 137.890 156.344 80.512  1.00 44.17  ? 465 ARG A CA  1 
ATOM   3289  C C   . ARG A 1 445 ? 136.371 156.251 80.565  1.00 40.77  ? 465 ARG A C   1 
ATOM   3290  O O   . ARG A 1 445 ? 135.708 156.287 79.532  1.00 41.08  ? 465 ARG A O   1 
ATOM   3291  C CB  . ARG A 1 445 ? 138.392 157.732 80.919  1.00 47.69  ? 465 ARG A CB  1 
ATOM   3292  C CG  . ARG A 1 445 ? 138.214 158.833 79.883  1.00 51.45  ? 465 ARG A CG  1 
ATOM   3293  C CD  . ARG A 1 445 ? 139.153 159.989 80.178  1.00 55.68  ? 465 ARG A CD  1 
ATOM   3294  N NE  . ARG A 1 445 ? 140.546 159.653 79.909  1.00 60.05  ? 465 ARG A NE  1 
ATOM   3295  C CZ  . ARG A 1 445 ? 141.059 159.430 78.700  1.00 64.50  ? 465 ARG A CZ  1 
ATOM   3296  N NH1 . ARG A 1 445 ? 140.323 159.600 77.613  1.00 64.90  ? 465 ARG A NH1 1 
ATOM   3297  N NH2 . ARG A 1 445 ? 142.322 159.054 78.580  1.00 66.04  ? 465 ARG A NH2 1 
ATOM   3298  N N   . TYR A 1 446 ? 135.846 156.153 81.786  1.00 37.90  ? 466 TYR A N   1 
ATOM   3299  C CA  . TYR A 1 446 ? 134.418 156.019 81.993  1.00 35.96  ? 466 TYR A CA  1 
ATOM   3300  C C   . TYR A 1 446 ? 133.869 157.267 82.671  1.00 35.60  ? 466 TYR A C   1 
ATOM   3301  O O   . TYR A 1 446 ? 134.580 157.945 83.409  1.00 36.41  ? 466 TYR A O   1 
ATOM   3302  C CB  . TYR A 1 446 ? 134.121 154.763 82.806  1.00 35.23  ? 466 TYR A CB  1 
ATOM   3303  C CG  . TYR A 1 446 ? 134.561 153.492 82.130  1.00 35.52  ? 466 TYR A CG  1 
ATOM   3304  C CD1 . TYR A 1 446 ? 135.874 153.063 82.202  1.00 36.04  ? 466 TYR A CD1 1 
ATOM   3305  C CD2 . TYR A 1 446 ? 133.675 152.742 81.376  1.00 36.26  ? 466 TYR A CD2 1 
ATOM   3306  C CE1 . TYR A 1 446 ? 136.287 151.896 81.581  1.00 36.49  ? 466 TYR A CE1 1 
ATOM   3307  C CE2 . TYR A 1 446 ? 134.071 151.576 80.743  1.00 36.83  ? 466 TYR A CE2 1 
ATOM   3308  C CZ  . TYR A 1 446 ? 135.382 151.148 80.850  1.00 36.73  ? 466 TYR A CZ  1 
ATOM   3309  O OH  . TYR A 1 446 ? 135.778 149.994 80.221  1.00 36.92  ? 466 TYR A OH  1 
ATOM   3310  N N   . GLU A 1 447 ? 132.592 157.548 82.389  1.00 35.27  ? 467 GLU A N   1 
ATOM   3311  C CA  . GLU A 1 447 ? 131.839 158.616 83.020  1.00 35.38  ? 467 GLU A CA  1 
ATOM   3312  C C   . GLU A 1 447 ? 130.711 157.986 83.826  1.00 33.98  ? 467 GLU A C   1 
ATOM   3313  O O   . GLU A 1 447 ? 129.925 157.216 83.282  1.00 34.77  ? 467 GLU A O   1 
ATOM   3314  C CB  . GLU A 1 447 ? 131.248 159.555 81.970  1.00 37.19  ? 467 GLU A CB  1 
ATOM   3315  C CG  . GLU A 1 447 ? 132.291 160.281 81.151  1.00 39.60  ? 467 GLU A CG  1 
ATOM   3316  C CD  . GLU A 1 447 ? 131.743 161.228 80.095  1.00 42.07  ? 467 GLU A CD  1 
ATOM   3317  O OE1 . GLU A 1 447 ? 130.554 161.098 79.735  1.00 42.58  ? 467 GLU A OE1 1 
ATOM   3318  O OE2 . GLU A 1 447 ? 132.505 162.109 79.645  1.00 42.87  ? 467 GLU A OE2 1 
ATOM   3319  N N   . ILE A 1 448 ? 130.666 158.275 85.128  1.00 33.09  ? 468 ILE A N   1 
ATOM   3320  C CA  . ILE A 1 448 ? 129.631 157.711 85.971  1.00 32.78  ? 468 ILE A CA  1 
ATOM   3321  C C   . ILE A 1 448 ? 128.449 158.673 85.967  1.00 33.09  ? 468 ILE A C   1 
ATOM   3322  O O   . ILE A 1 448 ? 128.594 159.856 86.279  1.00 34.31  ? 468 ILE A O   1 
ATOM   3323  C CB  . ILE A 1 448 ? 130.151 157.415 87.390  1.00 32.99  ? 468 ILE A CB  1 
ATOM   3324  C CG1 . ILE A 1 448 ? 131.491 156.677 87.359  1.00 33.21  ? 468 ILE A CG1 1 
ATOM   3325  C CG2 . ILE A 1 448 ? 129.107 156.648 88.187  1.00 33.29  ? 468 ILE A CG2 1 
ATOM   3326  C CD1 . ILE A 1 448 ? 131.478 155.398 86.542  1.00 33.54  ? 468 ILE A CD1 1 
ATOM   3327  N N   . MET A 1 449 ? 127.274 158.135 85.622  1.00 32.83  ? 469 MET A N   1 
ATOM   3328  C CA  . MET A 1 449 ? 126.084 158.944 85.434  1.00 32.79  ? 469 MET A CA  1 
ATOM   3329  C C   . MET A 1 449 ? 125.006 158.461 86.395  1.00 33.46  ? 469 MET A C   1 
ATOM   3330  O O   . MET A 1 449 ? 125.008 157.302 86.804  1.00 33.78  ? 469 MET A O   1 
ATOM   3331  C CB  . MET A 1 449 ? 125.560 158.828 84.002  1.00 32.54  ? 469 MET A CB  1 
ATOM   3332  C CG  . MET A 1 449 ? 126.639 158.921 82.967  1.00 33.05  ? 469 MET A CG  1 
ATOM   3333  S SD  . MET A 1 449 ? 126.043 159.653 81.445  1.00 34.69  ? 469 MET A SD  1 
ATOM   3334  C CE  . MET A 1 449 ? 126.599 161.334 81.710  1.00 35.06  ? 469 MET A CE  1 
ATOM   3335  N N   . ASN A 1 450 ? 124.086 159.368 86.732  1.00 33.98  ? 470 ASN A N   1 
ATOM   3336  C CA  . ASN A 1 450 ? 123.005 159.067 87.652  1.00 34.28  ? 470 ASN A CA  1 
ATOM   3337  C C   . ASN A 1 450 ? 121.699 159.553 87.038  1.00 34.19  ? 470 ASN A C   1 
ATOM   3338  O O   . ASN A 1 450 ? 121.642 160.645 86.483  1.00 34.59  ? 470 ASN A O   1 
ATOM   3339  C CB  . ASN A 1 450 ? 123.257 159.696 89.021  1.00 34.94  ? 470 ASN A CB  1 
ATOM   3340  C CG  . ASN A 1 450 ? 122.197 159.344 90.039  1.00 36.30  ? 470 ASN A CG  1 
ATOM   3341  O OD1 . ASN A 1 450 ? 121.751 158.203 90.093  1.00 36.28  ? 470 ASN A OD1 1 
ATOM   3342  N ND2 . ASN A 1 450 ? 121.786 160.313 90.843  1.00 37.63  ? 470 ASN A ND2 1 
ATOM   3343  N N   . PHE A 1 451 ? 120.659 158.723 87.137  1.00 34.31  ? 471 PHE A N   1 
ATOM   3344  C CA  . PHE A 1 451 ? 119.365 159.042 86.561  1.00 34.53  ? 471 PHE A CA  1 
ATOM   3345  C C   . PHE A 1 451 ? 118.534 159.764 87.615  1.00 38.06  ? 471 PHE A C   1 
ATOM   3346  O O   . PHE A 1 451 ? 118.181 159.177 88.634  1.00 39.00  ? 471 PHE A O   1 
ATOM   3347  C CB  . PHE A 1 451 ? 118.687 157.767 86.055  1.00 32.59  ? 471 PHE A CB  1 
ATOM   3348  C CG  . PHE A 1 451 ? 117.531 158.007 85.120  1.00 30.66  ? 471 PHE A CG  1 
ATOM   3349  C CD1 . PHE A 1 451 ? 117.683 158.823 84.013  1.00 30.17  ? 471 PHE A CD1 1 
ATOM   3350  C CD2 . PHE A 1 451 ? 116.295 157.423 85.342  1.00 29.88  ? 471 PHE A CD2 1 
ATOM   3351  C CE1 . PHE A 1 451 ? 116.625 159.049 83.148  1.00 29.69  ? 471 PHE A CE1 1 
ATOM   3352  C CE2 . PHE A 1 451 ? 115.241 157.651 84.474  1.00 29.47  ? 471 PHE A CE2 1 
ATOM   3353  C CZ  . PHE A 1 451 ? 115.406 158.465 83.381  1.00 29.28  ? 471 PHE A CZ  1 
ATOM   3354  N N   . LYS A 1 452 ? 118.241 161.043 87.366  1.00 42.62  ? 472 LYS A N   1 
ATOM   3355  C CA  . LYS A 1 452 ? 117.637 161.893 88.377  1.00 48.30  ? 472 LYS A CA  1 
ATOM   3356  C C   . LYS A 1 452 ? 116.368 162.539 87.833  1.00 53.57  ? 472 LYS A C   1 
ATOM   3357  O O   . LYS A 1 452 ? 116.143 162.576 86.626  1.00 53.73  ? 472 LYS A O   1 
ATOM   3358  C CB  . LYS A 1 452 ? 118.633 162.964 88.830  1.00 50.46  ? 472 LYS A CB  1 
ATOM   3359  C CG  . LYS A 1 452 ? 119.677 162.502 89.839  1.00 52.00  ? 472 LYS A CG  1 
ATOM   3360  C CD  . LYS A 1 452 ? 120.646 163.590 90.244  1.00 53.90  ? 472 LYS A CD  1 
ATOM   3361  C CE  . LYS A 1 452 ? 119.955 164.783 90.871  1.00 56.55  ? 472 LYS A CE  1 
ATOM   3362  N NZ  . LYS A 1 452 ? 120.769 166.014 90.751  1.00 57.67  ? 472 LYS A NZ  1 
ATOM   3363  N N   . GLU A 1 453 ? 115.549 163.043 88.762  1.00 61.99  ? 473 GLU A N   1 
ATOM   3364  C CA  . GLU A 1 453 ? 114.371 163.831 88.445  1.00 70.16  ? 473 GLU A CA  1 
ATOM   3365  C C   . GLU A 1 453 ? 114.666 165.294 88.762  1.00 76.37  ? 473 GLU A C   1 
ATOM   3366  O O   . GLU A 1 453 ? 114.940 165.635 89.910  1.00 79.08  ? 473 GLU A O   1 
ATOM   3367  C CB  . GLU A 1 453 ? 113.185 163.336 89.270  1.00 73.26  ? 473 GLU A CB  1 
ATOM   3368  C CG  . GLU A 1 453 ? 111.912 164.124 89.031  1.00 77.40  ? 473 GLU A CG  1 
ATOM   3369  C CD  . GLU A 1 453 ? 110.700 163.639 89.813  1.00 82.08  ? 473 GLU A CD  1 
ATOM   3370  O OE1 . GLU A 1 453 ? 110.855 162.721 90.650  1.00 82.84  ? 473 GLU A OE1 1 
ATOM   3371  O OE2 . GLU A 1 453 ? 109.594 164.169 89.577  1.00 84.43  ? 473 GLU A OE2 1 
ATOM   3372  N N   . MET A 1 454 ? 114.610 166.148 87.735  1.00 82.58  ? 474 MET A N   1 
ATOM   3373  C CA  . MET A 1 454 ? 115.017 167.538 87.857  1.00 89.43  ? 474 MET A CA  1 
ATOM   3374  C C   . MET A 1 454 ? 113.778 168.407 88.079  1.00 95.35  ? 474 MET A C   1 
ATOM   3375  O O   . MET A 1 454 ? 113.667 169.077 89.103  1.00 96.30  ? 474 MET A O   1 
ATOM   3376  C CB  . MET A 1 454 ? 115.751 167.990 86.590  1.00 90.79  ? 474 MET A CB  1 
ATOM   3377  C CG  . MET A 1 454 ? 116.815 167.006 86.122  1.00 91.52  ? 474 MET A CG  1 
ATOM   3378  S SD  . MET A 1 454 ? 118.043 166.553 87.383  1.00 95.29  ? 474 MET A SD  1 
ATOM   3379  C CE  . MET A 1 454 ? 118.679 168.161 87.857  1.00 97.72  ? 474 MET A CE  1 
ATOM   3380  N N   . GLY A 1 455 ? 112.845 168.375 87.119  1.00 100.75 ? 475 GLY A N   1 
ATOM   3381  C CA  . GLY A 1 455 ? 111.598 169.115 87.218  1.00 105.46 ? 475 GLY A CA  1 
ATOM   3382  C C   . GLY A 1 455 ? 110.427 168.195 87.555  1.00 110.24 ? 475 GLY A C   1 
ATOM   3383  O O   . GLY A 1 455 ? 110.620 167.053 87.971  1.00 109.34 ? 475 GLY A O   1 
ATOM   3384  N N   . LYS A 1 456 ? 109.208 168.714 87.386  1.00 115.87 ? 476 LYS A N   1 
ATOM   3385  C CA  . LYS A 1 456 ? 108.013 167.895 87.503  1.00 120.94 ? 476 LYS A CA  1 
ATOM   3386  C C   . LYS A 1 456 ? 107.802 167.166 86.178  1.00 119.06 ? 476 LYS A C   1 
ATOM   3387  O O   . LYS A 1 456 ? 107.713 167.797 85.126  1.00 117.54 ? 476 LYS A O   1 
ATOM   3388  C CB  . LYS A 1 456 ? 106.796 168.734 87.907  1.00 127.98 ? 476 LYS A CB  1 
ATOM   3389  C CG  . LYS A 1 456 ? 106.430 169.888 86.980  1.00 133.28 ? 476 LYS A CG  1 
ATOM   3390  C CD  . LYS A 1 456 ? 105.239 170.699 87.457  1.00 136.93 ? 476 LYS A CD  1 
ATOM   3391  C CE  . LYS A 1 456 ? 103.963 169.892 87.589  1.00 138.49 ? 476 LYS A CE  1 
ATOM   3392  N NZ  . LYS A 1 456 ? 103.598 169.215 86.321  1.00 138.77 ? 476 LYS A NZ  1 
ATOM   3393  N N   . ASP A 1 457 ? 107.759 165.829 86.249  1.00 117.62 ? 477 ASP A N   1 
ATOM   3394  C CA  . ASP A 1 457 ? 107.645 164.975 85.077  1.00 116.50 ? 477 ASP A CA  1 
ATOM   3395  C C   . ASP A 1 457 ? 108.764 165.317 84.095  1.00 110.73 ? 477 ASP A C   1 
ATOM   3396  O O   . ASP A 1 457 ? 108.509 165.686 82.949  1.00 111.17 ? 477 ASP A O   1 
ATOM   3397  C CB  . ASP A 1 457 ? 106.254 165.090 84.445  1.00 121.02 ? 477 ASP A CB  1 
ATOM   3398  C CG  . ASP A 1 457 ? 106.018 164.131 83.290  1.00 125.47 ? 477 ASP A CG  1 
ATOM   3399  O OD1 . ASP A 1 457 ? 106.860 163.231 83.093  1.00 127.55 ? 477 ASP A OD1 1 
ATOM   3400  O OD2 . ASP A 1 457 ? 105.023 164.322 82.573  1.00 127.46 ? 477 ASP A OD2 1 
ATOM   3401  N N   . TYR A 1 458 ? 110.007 165.210 84.575  1.00 102.97 ? 478 TYR A N   1 
ATOM   3402  C CA  . TYR A 1 458 ? 111.186 165.478 83.767  1.00 96.96  ? 478 TYR A CA  1 
ATOM   3403  C C   . TYR A 1 458 ? 112.370 164.723 84.365  1.00 86.57  ? 478 TYR A C   1 
ATOM   3404  O O   . TYR A 1 458 ? 112.813 165.050 85.462  1.00 88.03  ? 478 TYR A O   1 
ATOM   3405  C CB  . TYR A 1 458 ? 111.444 166.986 83.689  1.00 101.09 ? 478 TYR A CB  1 
ATOM   3406  C CG  . TYR A 1 458 ? 112.637 167.384 82.856  1.00 105.28 ? 478 TYR A CG  1 
ATOM   3407  C CD1 . TYR A 1 458 ? 112.783 166.948 81.548  1.00 107.35 ? 478 TYR A CD1 1 
ATOM   3408  C CD2 . TYR A 1 458 ? 113.639 168.176 83.390  1.00 108.09 ? 478 TYR A CD2 1 
ATOM   3409  C CE1 . TYR A 1 458 ? 113.882 167.308 80.785  1.00 110.37 ? 478 TYR A CE1 1 
ATOM   3410  C CE2 . TYR A 1 458 ? 114.743 168.550 82.640  1.00 109.84 ? 478 TYR A CE2 1 
ATOM   3411  C CZ  . TYR A 1 458 ? 114.867 168.112 81.333  1.00 111.28 ? 478 TYR A CZ  1 
ATOM   3412  O OH  . TYR A 1 458 ? 115.960 168.474 80.583  1.00 112.12 ? 478 TYR A OH  1 
ATOM   3413  N N   . PHE A 1 459 ? 112.866 163.707 83.648  1.00 75.50  ? 479 PHE A N   1 
ATOM   3414  C CA  . PHE A 1 459 ? 113.949 162.870 84.148  1.00 67.96  ? 479 PHE A CA  1 
ATOM   3415  C C   . PHE A 1 459 ? 115.102 162.893 83.153  1.00 61.59  ? 479 PHE A C   1 
ATOM   3416  O O   . PHE A 1 459 ? 114.879 162.962 81.948  1.00 62.79  ? 479 PHE A O   1 
ATOM   3417  C CB  . PHE A 1 459 ? 113.477 161.434 84.400  1.00 68.64  ? 479 PHE A CB  1 
ATOM   3418  C CG  . PHE A 1 459 ? 112.280 161.328 85.312  1.00 71.60  ? 479 PHE A CG  1 
ATOM   3419  C CD1 . PHE A 1 459 ? 111.011 161.624 84.840  1.00 75.10  ? 479 PHE A CD1 1 
ATOM   3420  C CD2 . PHE A 1 459 ? 112.420 160.989 86.650  1.00 72.87  ? 479 PHE A CD2 1 
ATOM   3421  C CE1 . PHE A 1 459 ? 109.905 161.543 85.673  1.00 77.65  ? 479 PHE A CE1 1 
ATOM   3422  C CE2 . PHE A 1 459 ? 111.315 160.927 87.485  1.00 75.21  ? 479 PHE A CE2 1 
ATOM   3423  C CZ  . PHE A 1 459 ? 110.059 161.197 86.994  1.00 77.49  ? 479 PHE A CZ  1 
ATOM   3424  N N   . ASP A 1 460 ? 116.334 162.827 83.668  1.00 54.77  ? 480 ASP A N   1 
ATOM   3425  C CA  . ASP A 1 460 ? 117.507 163.049 82.844  1.00 49.89  ? 480 ASP A CA  1 
ATOM   3426  C C   . ASP A 1 460 ? 118.711 162.347 83.466  1.00 44.43  ? 480 ASP A C   1 
ATOM   3427  O O   . ASP A 1 460 ? 118.746 162.104 84.667  1.00 44.08  ? 480 ASP A O   1 
ATOM   3428  C CB  . ASP A 1 460 ? 117.748 164.551 82.689  1.00 51.98  ? 480 ASP A CB  1 
ATOM   3429  C CG  . ASP A 1 460 ? 118.833 164.909 81.693  1.00 54.37  ? 480 ASP A CG  1 
ATOM   3430  O OD1 . ASP A 1 460 ? 119.377 163.972 81.072  1.00 55.20  ? 480 ASP A OD1 1 
ATOM   3431  O OD2 . ASP A 1 460 ? 119.153 166.107 81.578  1.00 56.38  ? 480 ASP A OD2 1 
ATOM   3432  N N   . TYR A 1 461 ? 119.701 162.038 82.624  1.00 40.96  ? 481 TYR A N   1 
ATOM   3433  C CA  . TYR A 1 461 ? 120.974 161.512 83.086  1.00 38.64  ? 481 TYR A CA  1 
ATOM   3434  C C   . TYR A 1 461 ? 121.903 162.666 83.448  1.00 39.34  ? 481 TYR A C   1 
ATOM   3435  O O   . TYR A 1 461 ? 122.080 163.595 82.666  1.00 40.25  ? 481 TYR A O   1 
ATOM   3436  C CB  . TYR A 1 461 ? 121.614 160.621 82.022  1.00 36.52  ? 481 TYR A CB  1 
ATOM   3437  C CG  . TYR A 1 461 ? 120.892 159.321 81.786  1.00 35.06  ? 481 TYR A CG  1 
ATOM   3438  C CD1 . TYR A 1 461 ? 119.841 159.229 80.886  1.00 34.50  ? 481 TYR A CD1 1 
ATOM   3439  C CD2 . TYR A 1 461 ? 121.238 158.182 82.492  1.00 34.62  ? 481 TYR A CD2 1 
ATOM   3440  C CE1 . TYR A 1 461 ? 119.171 158.034 80.681  1.00 34.07  ? 481 TYR A CE1 1 
ATOM   3441  C CE2 . TYR A 1 461 ? 120.583 156.978 82.294  1.00 33.92  ? 481 TYR A CE2 1 
ATOM   3442  C CZ  . TYR A 1 461 ? 119.542 156.904 81.389  1.00 33.62  ? 481 TYR A CZ  1 
ATOM   3443  O OH  . TYR A 1 461 ? 118.900 155.707 81.208  1.00 33.49  ? 481 TYR A OH  1 
ATOM   3444  N N   . ILE A 1 462 ? 122.512 162.571 84.631  1.00 39.24  ? 482 ILE A N   1 
ATOM   3445  C CA  . ILE A 1 462 ? 123.407 163.594 85.138  1.00 39.12  ? 482 ILE A CA  1 
ATOM   3446  C C   . ILE A 1 462 ? 124.780 162.977 85.374  1.00 38.37  ? 482 ILE A C   1 
ATOM   3447  O O   . ILE A 1 462 ? 124.898 161.952 86.041  1.00 37.69  ? 482 ILE A O   1 
ATOM   3448  C CB  . ILE A 1 462 ? 122.849 164.207 86.436  1.00 39.96  ? 482 ILE A CB  1 
ATOM   3449  C CG1 . ILE A 1 462 ? 121.548 164.984 86.203  1.00 39.91  ? 482 ILE A CG1 1 
ATOM   3450  C CG2 . ILE A 1 462 ? 123.926 165.028 87.138  1.00 40.68  ? 482 ILE A CG2 1 
ATOM   3451  C CD1 . ILE A 1 462 ? 121.524 165.825 84.944  1.00 39.97  ? 482 ILE A CD1 1 
ATOM   3452  N N   . ASN A 1 463 ? 125.812 163.634 84.841  1.00 38.68  ? 483 ASN A N   1 
ATOM   3453  C CA  . ASN A 1 463 ? 127.179 163.184 85.024  1.00 38.99  ? 483 ASN A CA  1 
ATOM   3454  C C   . ASN A 1 463 ? 127.602 163.467 86.462  1.00 38.58  ? 483 ASN A C   1 
ATOM   3455  O O   . ASN A 1 463 ? 127.693 164.627 86.864  1.00 38.87  ? 483 ASN A O   1 
ATOM   3456  C CB  . ASN A 1 463 ? 128.139 163.865 84.050  1.00 40.01  ? 483 ASN A CB  1 
ATOM   3457  C CG  . ASN A 1 463 ? 129.473 163.157 83.984  1.00 41.06  ? 483 ASN A CG  1 
ATOM   3458  O OD1 . ASN A 1 463 ? 129.995 162.702 84.998  1.00 41.52  ? 483 ASN A OD1 1 
ATOM   3459  N ND2 . ASN A 1 463 ? 130.025 163.033 82.788  1.00 41.58  ? 483 ASN A ND2 1 
ATOM   3460  N N   . VAL A 1 464 ? 127.860 162.400 87.227  1.00 38.15  ? 484 VAL A N   1 
ATOM   3461  C CA  . VAL A 1 464 ? 128.161 162.544 88.642  1.00 37.86  ? 484 VAL A CA  1 
ATOM   3462  C C   . VAL A 1 464 ? 129.566 162.042 88.949  1.00 38.06  ? 484 VAL A C   1 
ATOM   3463  O O   . VAL A 1 464 ? 129.924 161.915 90.121  1.00 40.23  ? 484 VAL A O   1 
ATOM   3464  C CB  . VAL A 1 464 ? 127.131 161.815 89.524  1.00 38.08  ? 484 VAL A CB  1 
ATOM   3465  C CG1 . VAL A 1 464 ? 125.732 162.374 89.317  1.00 38.39  ? 484 VAL A CG1 1 
ATOM   3466  C CG2 . VAL A 1 464 ? 127.165 160.309 89.310  1.00 38.05  ? 484 VAL A CG2 1 
ATOM   3467  N N   . GLY A 1 465 ? 130.366 161.758 87.918  1.00 38.00  ? 485 GLY A N   1 
ATOM   3468  C CA  . GLY A 1 465 ? 131.751 161.403 88.168  1.00 38.10  ? 485 GLY A CA  1 
ATOM   3469  C C   . GLY A 1 465 ? 132.448 160.806 86.953  1.00 37.43  ? 485 GLY A C   1 
ATOM   3470  O O   . GLY A 1 465 ? 131.902 160.783 85.856  1.00 37.53  ? 485 GLY A O   1 
ATOM   3471  N N   . SER A 1 466 ? 133.653 160.293 87.196  1.00 37.45  ? 486 SER A N   1 
ATOM   3472  C CA  . SER A 1 466 ? 134.501 159.727 86.168  1.00 37.82  ? 486 SER A CA  1 
ATOM   3473  C C   . SER A 1 466 ? 135.364 158.633 86.782  1.00 38.40  ? 486 SER A C   1 
ATOM   3474  O O   . SER A 1 466 ? 135.479 158.532 88.001  1.00 39.81  ? 486 SER A O   1 
ATOM   3475  C CB  . SER A 1 466 ? 135.343 160.799 85.529  1.00 38.25  ? 486 SER A CB  1 
ATOM   3476  O OG  . SER A 1 466 ? 136.441 160.239 84.816  1.00 38.47  ? 486 SER A OG  1 
ATOM   3477  N N   . TRP A 1 467 ? 135.978 157.838 85.907  1.00 39.38  ? 487 TRP A N   1 
ATOM   3478  C CA  . TRP A 1 467 ? 136.869 156.771 86.319  1.00 40.68  ? 487 TRP A CA  1 
ATOM   3479  C C   . TRP A 1 467 ? 137.933 156.599 85.245  1.00 43.41  ? 487 TRP A C   1 
ATOM   3480  O O   . TRP A 1 467 ? 137.592 156.402 84.079  1.00 44.01  ? 487 TRP A O   1 
ATOM   3481  C CB  . TRP A 1 467 ? 136.068 155.489 86.545  1.00 39.59  ? 487 TRP A CB  1 
ATOM   3482  C CG  . TRP A 1 467 ? 136.850 154.381 87.171  1.00 39.38  ? 487 TRP A CG  1 
ATOM   3483  C CD1 . TRP A 1 467 ? 136.801 153.989 88.475  1.00 40.24  ? 487 TRP A CD1 1 
ATOM   3484  C CD2 . TRP A 1 467 ? 137.767 153.489 86.517  1.00 39.30  ? 487 TRP A CD2 1 
ATOM   3485  N NE1 . TRP A 1 467 ? 137.627 152.920 88.684  1.00 40.26  ? 487 TRP A NE1 1 
ATOM   3486  C CE2 . TRP A 1 467 ? 138.233 152.590 87.501  1.00 40.21  ? 487 TRP A CE2 1 
ATOM   3487  C CE3 . TRP A 1 467 ? 138.241 153.358 85.208  1.00 39.56  ? 487 TRP A CE3 1 
ATOM   3488  C CZ2 . TRP A 1 467 ? 139.162 151.591 87.214  1.00 40.86  ? 487 TRP A CZ2 1 
ATOM   3489  C CZ3 . TRP A 1 467 ? 139.152 152.365 84.925  1.00 40.31  ? 487 TRP A CZ3 1 
ATOM   3490  C CH2 . TRP A 1 467 ? 139.601 151.491 85.914  1.00 40.88  ? 487 TRP A CH2 1 
ATOM   3491  N N   . ASP A 1 468 ? 139.210 156.684 85.634  1.00 47.66  ? 488 ASP A N   1 
ATOM   3492  C CA  . ASP A 1 468 ? 140.277 156.696 84.647  1.00 51.82  ? 488 ASP A CA  1 
ATOM   3493  C C   . ASP A 1 468 ? 141.539 156.067 85.228  1.00 56.13  ? 488 ASP A C   1 
ATOM   3494  O O   . ASP A 1 468 ? 142.218 156.677 86.044  1.00 57.88  ? 488 ASP A O   1 
ATOM   3495  C CB  . ASP A 1 468 ? 140.541 158.121 84.155  1.00 52.89  ? 488 ASP A CB  1 
ATOM   3496  C CG  . ASP A 1 468 ? 141.446 158.191 82.938  1.00 54.69  ? 488 ASP A CG  1 
ATOM   3497  O OD1 . ASP A 1 468 ? 141.793 157.119 82.402  1.00 55.60  ? 488 ASP A OD1 1 
ATOM   3498  O OD2 . ASP A 1 468 ? 141.791 159.318 82.532  1.00 56.07  ? 488 ASP A OD2 1 
ATOM   3499  N N   . ASN A 1 469 ? 141.860 154.859 84.755  1.00 60.34  ? 489 ASN A N   1 
ATOM   3500  C CA  . ASN A 1 469 ? 143.072 154.150 85.141  1.00 64.03  ? 489 ASN A CA  1 
ATOM   3501  C C   . ASN A 1 469 ? 143.132 153.986 86.660  1.00 64.20  ? 489 ASN A C   1 
ATOM   3502  O O   . ASN A 1 469 ? 144.169 154.231 87.276  1.00 64.79  ? 489 ASN A O   1 
ATOM   3503  C CB  . ASN A 1 469 ? 144.331 154.841 84.610  1.00 67.22  ? 489 ASN A CB  1 
ATOM   3504  C CG  . ASN A 1 469 ? 144.298 155.059 83.113  1.00 70.43  ? 489 ASN A CG  1 
ATOM   3505  O OD1 . ASN A 1 469 ? 143.293 154.779 82.462  1.00 70.51  ? 489 ASN A OD1 1 
ATOM   3506  N ND2 . ASN A 1 469 ? 145.379 155.588 82.565  1.00 72.13  ? 489 ASN A ND2 1 
ATOM   3507  N N   . GLY A 1 470 ? 142.017 153.545 87.252  1.00 63.72  ? 490 GLY A N   1 
ATOM   3508  C CA  . GLY A 1 470 ? 142.003 153.143 88.649  1.00 64.83  ? 490 GLY A CA  1 
ATOM   3509  C C   . GLY A 1 470 ? 141.408 154.205 89.570  1.00 66.05  ? 490 GLY A C   1 
ATOM   3510  O O   . GLY A 1 470 ? 140.838 153.872 90.608  1.00 66.51  ? 490 GLY A O   1 
ATOM   3511  N N   . GLU A 1 471 ? 141.532 155.482 89.196  1.00 66.64  ? 491 GLU A N   1 
ATOM   3512  C CA  . GLU A 1 471 ? 141.028 156.559 90.033  1.00 67.68  ? 491 GLU A CA  1 
ATOM   3513  C C   . GLU A 1 471 ? 139.553 156.800 89.719  1.00 64.11  ? 491 GLU A C   1 
ATOM   3514  O O   . GLU A 1 471 ? 139.173 157.051 88.573  1.00 63.43  ? 491 GLU A O   1 
ATOM   3515  C CB  . GLU A 1 471 ? 141.882 157.823 89.885  1.00 71.94  ? 491 GLU A CB  1 
ATOM   3516  C CG  . GLU A 1 471 ? 141.855 158.453 88.505  1.00 75.63  ? 491 GLU A CG  1 
ATOM   3517  C CD  . GLU A 1 471 ? 143.056 159.338 88.210  1.00 79.49  ? 491 GLU A CD  1 
ATOM   3518  O OE1 . GLU A 1 471 ? 143.882 158.947 87.362  1.00 80.54  ? 491 GLU A OE1 1 
ATOM   3519  O OE2 . GLU A 1 471 ? 143.168 160.414 88.835  1.00 81.58  ? 491 GLU A OE2 1 
ATOM   3520  N N   . LEU A 1 472 ? 138.737 156.711 90.778  1.00 62.23  ? 492 LEU A N   1 
ATOM   3521  C CA  . LEU A 1 472 ? 137.331 157.076 90.735  1.00 61.13  ? 492 LEU A CA  1 
ATOM   3522  C C   . LEU A 1 472 ? 137.160 158.462 91.354  1.00 62.96  ? 492 LEU A C   1 
ATOM   3523  O O   . LEU A 1 472 ? 137.418 158.665 92.541  1.00 64.91  ? 492 LEU A O   1 
ATOM   3524  C CB  . LEU A 1 472 ? 136.511 156.029 91.496  1.00 59.46  ? 492 LEU A CB  1 
ATOM   3525  C CG  . LEU A 1 472 ? 135.064 155.819 91.032  1.00 59.13  ? 492 LEU A CG  1 
ATOM   3526  C CD1 . LEU A 1 472 ? 134.339 154.865 91.966  1.00 58.23  ? 492 LEU A CD1 1 
ATOM   3527  C CD2 . LEU A 1 472 ? 134.281 157.118 90.928  1.00 59.76  ? 492 LEU A CD2 1 
ATOM   3528  N N   . LYS A 1 473 ? 136.748 159.418 90.523  1.00 65.02  ? 493 LYS A N   1 
ATOM   3529  C CA  . LYS A 1 473 ? 136.277 160.704 91.011  1.00 68.52  ? 493 LYS A CA  1 
ATOM   3530  C C   . LYS A 1 473 ? 134.753 160.704 90.951  1.00 70.10  ? 493 LYS A C   1 
ATOM   3531  O O   . LYS A 1 473 ? 134.178 160.314 89.943  1.00 71.23  ? 493 LYS A O   1 
ATOM   3532  C CB  . LYS A 1 473 ? 136.882 161.836 90.182  1.00 70.77  ? 493 LYS A CB  1 
ATOM   3533  C CG  . LYS A 1 473 ? 138.160 162.435 90.749  1.00 74.01  ? 493 LYS A CG  1 
ATOM   3534  C CD  . LYS A 1 473 ? 138.565 163.724 90.073  1.00 76.88  ? 493 LYS A CD  1 
ATOM   3535  C CE  . LYS A 1 473 ? 138.695 163.614 88.567  1.00 79.07  ? 493 LYS A CE  1 
ATOM   3536  N NZ  . LYS A 1 473 ? 139.608 162.518 88.163  1.00 79.98  ? 493 LYS A NZ  1 
ATOM   3537  N N   . MET A 1 474 ? 134.097 161.072 92.052  1.00 71.48  ? 494 MET A N   1 
ATOM   3538  C CA  . MET A 1 474 ? 132.643 161.120 92.060  1.00 71.84  ? 494 MET A CA  1 
ATOM   3539  C C   . MET A 1 474 ? 132.168 162.202 93.020  1.00 78.00  ? 494 MET A C   1 
ATOM   3540  O O   . MET A 1 474 ? 132.594 162.243 94.176  1.00 80.41  ? 494 MET A O   1 
ATOM   3541  C CB  . MET A 1 474 ? 132.038 159.777 92.481  1.00 68.92  ? 494 MET A CB  1 
ATOM   3542  C CG  . MET A 1 474 ? 131.442 158.991 91.333  1.00 68.26  ? 494 MET A CG  1 
ATOM   3543  S SD  . MET A 1 474 ? 130.525 157.540 91.907  1.00 67.71  ? 494 MET A SD  1 
ATOM   3544  C CE  . MET A 1 474 ? 128.849 158.037 91.508  1.00 67.98  ? 494 MET A CE  1 
ATOM   3545  N N   . ASP A 1 475 ? 131.254 163.058 92.543  1.00 84.00  ? 495 ASP A N   1 
ATOM   3546  C CA  . ASP A 1 475 ? 130.551 163.972 93.429  1.00 89.64  ? 495 ASP A CA  1 
ATOM   3547  C C   . ASP A 1 475 ? 129.501 163.170 94.198  1.00 95.83  ? 495 ASP A C   1 
ATOM   3548  O O   . ASP A 1 475 ? 128.872 162.272 93.641  1.00 95.47  ? 495 ASP A O   1 
ATOM   3549  C CB  . ASP A 1 475 ? 130.016 165.198 92.677  1.00 89.19  ? 495 ASP A CB  1 
ATOM   3550  C CG  . ASP A 1 475 ? 128.703 165.027 91.930  1.00 89.96  ? 495 ASP A CG  1 
ATOM   3551  O OD1 . ASP A 1 475 ? 127.987 164.046 92.201  1.00 89.54  ? 495 ASP A OD1 1 
ATOM   3552  O OD2 . ASP A 1 475 ? 128.417 165.879 91.068  1.00 91.48  ? 495 ASP A OD2 1 
ATOM   3553  N N   . ASP A 1 476 ? 129.349 163.483 95.489  1.00 104.06 ? 496 ASP A N   1 
ATOM   3554  C CA  . ASP A 1 476 ? 128.349 162.840 96.325  1.00 112.52 ? 496 ASP A CA  1 
ATOM   3555  C C   . ASP A 1 476 ? 127.284 163.852 96.749  1.00 114.85 ? 496 ASP A C   1 
ATOM   3556  O O   . ASP A 1 476 ? 126.491 163.568 97.644  1.00 115.39 ? 496 ASP A O   1 
ATOM   3557  C CB  . ASP A 1 476 ? 128.988 162.186 97.553  1.00 119.17 ? 496 ASP A CB  1 
ATOM   3558  C CG  . ASP A 1 476 ? 128.029 161.328 98.361  1.00 126.38 ? 496 ASP A CG  1 
ATOM   3559  O OD1 . ASP A 1 476 ? 126.870 161.161 97.919  1.00 128.67 ? 496 ASP A OD1 1 
ATOM   3560  O OD2 . ASP A 1 476 ? 128.439 160.849 99.434  1.00 129.32 ? 496 ASP A OD2 1 
ATOM   3561  N N   . ASP A 1 477 ? 127.263 165.028 96.108  1.00 117.05 ? 497 ASP A N   1 
ATOM   3562  C CA  . ASP A 1 477 ? 126.286 166.061 96.418  1.00 119.84 ? 497 ASP A CA  1 
ATOM   3563  C C   . ASP A 1 477 ? 125.110 165.960 95.448  1.00 117.76 ? 497 ASP A C   1 
ATOM   3564  O O   . ASP A 1 477 ? 123.954 166.007 95.866  1.00 119.33 ? 497 ASP A O   1 
ATOM   3565  C CB  . ASP A 1 477 ? 126.927 167.450 96.387  1.00 124.97 ? 497 ASP A CB  1 
ATOM   3566  C CG  . ASP A 1 477 ? 128.087 167.611 97.355  1.00 129.37 ? 497 ASP A CG  1 
ATOM   3567  O OD1 . ASP A 1 477 ? 128.378 166.653 98.104  1.00 129.31 ? 497 ASP A OD1 1 
ATOM   3568  O OD2 . ASP A 1 477 ? 128.694 168.694 97.349  1.00 132.27 ? 497 ASP A OD2 1 
ATOM   3569  N N   . GLU A 1 478 ? 125.416 165.836 94.150  1.00 114.71 ? 498 GLU A N   1 
ATOM   3570  C CA  . GLU A 1 478 ? 124.388 165.755 93.121  1.00 113.30 ? 498 GLU A CA  1 
ATOM   3571  C C   . GLU A 1 478 ? 123.563 164.485 93.319  1.00 109.93 ? 498 GLU A C   1 
ATOM   3572  O O   . GLU A 1 478 ? 122.341 164.517 93.203  1.00 109.15 ? 498 GLU A O   1 
ATOM   3573  C CB  . GLU A 1 478 ? 125.001 165.779 91.719  1.00 113.87 ? 498 GLU A CB  1 
ATOM   3574  C CG  . GLU A 1 478 ? 125.479 167.152 91.289  1.00 115.25 ? 498 GLU A CG  1 
ATOM   3575  C CD  . GLU A 1 478 ? 124.395 168.216 91.294  1.00 116.58 ? 498 GLU A CD  1 
ATOM   3576  O OE1 . GLU A 1 478 ? 123.483 168.133 90.450  1.00 115.66 ? 498 GLU A OE1 1 
ATOM   3577  O OE2 . GLU A 1 478 ? 124.457 169.115 92.155  1.00 117.79 ? 498 GLU A OE2 1 
ATOM   3578  N N   . VAL A 1 479 ? 124.241 163.371 93.613  1.00 106.98 ? 499 VAL A N   1 
ATOM   3579  C CA  . VAL A 1 479 ? 123.561 162.133 93.958  1.00 107.16 ? 499 VAL A CA  1 
ATOM   3580  C C   . VAL A 1 479 ? 123.324 162.132 95.467  1.00 111.65 ? 499 VAL A C   1 
ATOM   3581  O O   . VAL A 1 479 ? 124.247 162.377 96.239  1.00 111.55 ? 499 VAL A O   1 
ATOM   3582  C CB  . VAL A 1 479 ? 124.347 160.891 93.491  1.00 104.48 ? 499 VAL A CB  1 
ATOM   3583  C CG1 . VAL A 1 479 ? 125.809 160.915 93.918  1.00 105.10 ? 499 VAL A CG1 1 
ATOM   3584  C CG2 . VAL A 1 479 ? 123.676 159.605 93.950  1.00 103.71 ? 499 VAL A CG2 1 
ATOM   3585  N N   . TRP A 1 480 ? 122.076 161.858 95.871  1.00 116.60 ? 500 TRP A N   1 
ATOM   3586  C CA  . TRP A 1 480 ? 121.682 161.849 97.272  1.00 121.08 ? 500 TRP A CA  1 
ATOM   3587  C C   . TRP A 1 480 ? 121.976 163.193 97.931  1.00 130.15 ? 500 TRP A C   1 
ATOM   3588  O O   . TRP A 1 480 ? 122.849 163.286 98.792  1.00 132.98 ? 500 TRP A O   1 
ATOM   3589  C CB  . TRP A 1 480 ? 122.375 160.709 98.025  1.00 117.29 ? 500 TRP A CB  1 
ATOM   3590  C CG  . TRP A 1 480 ? 122.111 159.359 97.444  1.00 114.60 ? 500 TRP A CG  1 
ATOM   3591  C CD1 . TRP A 1 480 ? 120.903 158.840 97.079  1.00 114.85 ? 500 TRP A CD1 1 
ATOM   3592  C CD2 . TRP A 1 480 ? 123.083 158.332 97.192  1.00 110.93 ? 500 TRP A CD2 1 
ATOM   3593  N NE1 . TRP A 1 480 ? 121.059 157.566 96.601  1.00 112.56 ? 500 TRP A NE1 1 
ATOM   3594  C CE2 . TRP A 1 480 ? 122.385 157.227 96.661  1.00 110.35 ? 500 TRP A CE2 1 
ATOM   3595  C CE3 . TRP A 1 480 ? 124.469 158.246 97.358  1.00 108.33 ? 500 TRP A CE3 1 
ATOM   3596  C CZ2 . TRP A 1 480 ? 123.035 156.050 96.292  1.00 107.51 ? 500 TRP A CZ2 1 
ATOM   3597  C CZ3 . TRP A 1 480 ? 125.111 157.088 96.985  1.00 106.20 ? 500 TRP A CZ3 1 
ATOM   3598  C CH2 . TRP A 1 480 ? 124.400 156.012 96.458  1.00 106.13 ? 500 TRP A CH2 1 
ATOM   3599  N N   . SER A 1 481 ? 121.214 164.222 97.548  1.00 137.73 ? 501 SER A N   1 
ATOM   3600  C CA  . SER A 1 481 ? 121.352 165.550 98.130  1.00 145.93 ? 501 SER A CA  1 
ATOM   3601  C C   . SER A 1 481 ? 120.791 165.565 99.553  1.00 152.77 ? 501 SER A C   1 
ATOM   3602  O O   . SER A 1 481 ? 119.890 166.344 99.864  1.00 153.37 ? 501 SER A O   1 
ATOM   3603  C CB  . SER A 1 481 ? 120.690 166.587 97.256  1.00 147.48 ? 501 SER A CB  1 
ATOM   3604  O OG  . SER A 1 481 ? 120.827 167.887 97.811  1.00 147.92 ? 501 SER A OG  1 
ATOM   3605  N N   . LYS A 1 482 ? 121.368 164.711 100.408 1.00 158.39 ? 502 LYS A N   1 
ATOM   3606  C CA  . LYS A 1 482 ? 120.948 164.521 101.789 1.00 162.79 ? 502 LYS A CA  1 
ATOM   3607  C C   . LYS A 1 482 ? 121.817 163.428 102.406 1.00 164.99 ? 502 LYS A C   1 
ATOM   3608  O O   . LYS A 1 482 ? 122.491 162.688 101.691 1.00 164.74 ? 502 LYS A O   1 
ATOM   3609  C CB  . LYS A 1 482 ? 119.465 164.144 101.889 1.00 165.43 ? 502 LYS A CB  1 
ATOM   3610  C CG  . LYS A 1 482 ? 119.023 162.972 101.020 1.00 167.30 ? 502 LYS A CG  1 
ATOM   3611  C CD  . LYS A 1 482 ? 117.565 162.597 101.196 1.00 169.82 ? 502 LYS A CD  1 
ATOM   3612  C CE  . LYS A 1 482 ? 117.004 161.783 100.048 1.00 170.63 ? 502 LYS A CE  1 
ATOM   3613  N NZ  . LYS A 1 482 ? 116.879 162.583 98.806  1.00 170.39 ? 502 LYS A NZ  1 
ATOM   3614  N N   . LYS A 1 483 ? 121.791 163.328 103.739 1.00 169.13 ? 503 LYS A N   1 
ATOM   3615  C CA  . LYS A 1 483 ? 122.552 162.305 104.443 1.00 171.85 ? 503 LYS A CA  1 
ATOM   3616  C C   . LYS A 1 483 ? 121.799 160.976 104.429 1.00 167.51 ? 503 LYS A C   1 
ATOM   3617  O O   . LYS A 1 483 ? 122.383 159.937 104.734 1.00 163.75 ? 503 LYS A O   1 
ATOM   3618  C CB  . LYS A 1 483 ? 122.855 162.745 105.879 1.00 175.88 ? 503 LYS A CB  1 
ATOM   3619  C CG  . LYS A 1 483 ? 123.801 163.934 106.010 1.00 177.65 ? 503 LYS A CG  1 
ATOM   3620  C CD  . LYS A 1 483 ? 125.103 163.811 105.227 1.00 177.86 ? 503 LYS A CD  1 
ATOM   3621  C CE  . LYS A 1 483 ? 125.928 162.586 105.571 1.00 177.63 ? 503 LYS A CE  1 
ATOM   3622  N NZ  . LYS A 1 483 ? 126.495 162.659 106.939 1.00 177.77 ? 503 LYS A NZ  1 
ATOM   3623  N N   . SER A 1 484 ? 120.506 161.017 104.078 1.00 163.29 ? 504 SER A N   1 
ATOM   3624  C CA  . SER A 1 484 ? 119.694 159.815 103.967 1.00 159.05 ? 504 SER A CA  1 
ATOM   3625  C C   . SER A 1 484 ? 119.719 159.309 102.526 1.00 151.00 ? 504 SER A C   1 
ATOM   3626  O O   . SER A 1 484 ? 118.775 159.523 101.770 1.00 149.27 ? 504 SER A O   1 
ATOM   3627  C CB  . SER A 1 484 ? 118.287 160.066 104.446 1.00 161.06 ? 504 SER A CB  1 
ATOM   3628  O OG  . SER A 1 484 ? 118.278 160.413 105.823 1.00 162.42 ? 504 SER A OG  1 
ATOM   3629  N N   . ASN A 1 485 ? 120.818 158.632 102.168 1.00 141.11 ? 505 ASN A N   1 
ATOM   3630  C CA  . ASN A 1 485 ? 120.985 158.025 100.855 1.00 132.12 ? 505 ASN A CA  1 
ATOM   3631  C C   . ASN A 1 485 ? 120.201 156.715 100.808 1.00 130.20 ? 505 ASN A C   1 
ATOM   3632  O O   . ASN A 1 485 ? 119.411 156.436 101.708 1.00 130.79 ? 505 ASN A O   1 
ATOM   3633  C CB  . ASN A 1 485 ? 122.466 157.802 100.532 1.00 126.88 ? 505 ASN A CB  1 
ATOM   3634  C CG  . ASN A 1 485 ? 123.122 156.772 101.427 1.00 123.59 ? 505 ASN A CG  1 
ATOM   3635  O OD1 . ASN A 1 485 ? 122.666 156.530 102.542 1.00 124.51 ? 505 ASN A OD1 1 
ATOM   3636  N ND2 . ASN A 1 485 ? 124.203 156.172 100.957 1.00 121.63 ? 505 ASN A ND2 1 
ATOM   3637  N N   . ILE A 1 486 ? 120.427 155.907 99.761  1.00 126.63 ? 506 ILE A N   1 
ATOM   3638  C CA  . ILE A 1 486 ? 119.809 154.594 99.666  1.00 123.13 ? 506 ILE A CA  1 
ATOM   3639  C C   . ILE A 1 486 ? 120.267 153.754 100.854 1.00 123.08 ? 506 ILE A C   1 
ATOM   3640  O O   . ILE A 1 486 ? 121.407 153.878 101.308 1.00 120.03 ? 506 ILE A O   1 
ATOM   3641  C CB  . ILE A 1 486 ? 120.144 153.893 98.333  1.00 118.09 ? 506 ILE A CB  1 
ATOM   3642  C CG1 . ILE A 1 486 ? 119.177 152.745 98.027  1.00 119.02 ? 506 ILE A CG1 1 
ATOM   3643  C CG2 . ILE A 1 486 ? 121.591 153.418 98.313  1.00 114.31 ? 506 ILE A CG2 1 
ATOM   3644  C CD1 . ILE A 1 486 ? 117.749 153.179 97.773  1.00 120.48 ? 506 ILE A CD1 1 
ATOM   3645  N N   . ILE A 1 487 ? 119.364 152.892 101.336 1.00 124.82 ? 507 ILE A N   1 
ATOM   3646  C CA  . ILE A 1 487 ? 119.674 152.030 102.463 1.00 125.52 ? 507 ILE A CA  1 
ATOM   3647  C C   . ILE A 1 487 ? 120.867 151.169 102.065 1.00 119.12 ? 507 ILE A C   1 
ATOM   3648  O O   . ILE A 1 487 ? 120.817 150.447 101.067 1.00 115.39 ? 507 ILE A O   1 
ATOM   3649  C CB  . ILE A 1 487 ? 118.454 151.196 102.906 1.00 130.40 ? 507 ILE A CB  1 
ATOM   3650  C CG1 . ILE A 1 487 ? 117.319 152.106 103.392 1.00 132.20 ? 507 ILE A CG1 1 
ATOM   3651  C CG2 . ILE A 1 487 ? 118.850 150.163 103.959 1.00 131.93 ? 507 ILE A CG2 1 
ATOM   3652  C CD1 . ILE A 1 487 ? 116.034 151.393 103.760 1.00 133.00 ? 507 ILE A CD1 1 
ATOM   3653  N N   . ARG A 1 488 ? 121.943 151.299 102.850 1.00 115.93 ? 508 ARG A N   1 
ATOM   3654  C CA  . ARG A 1 488 ? 123.200 150.637 102.555 1.00 114.38 ? 508 ARG A CA  1 
ATOM   3655  C C   . ARG A 1 488 ? 122.921 149.147 102.414 1.00 104.49 ? 508 ARG A C   1 
ATOM   3656  O O   . ARG A 1 488 ? 122.310 148.542 103.295 1.00 105.91 ? 508 ARG A O   1 
ATOM   3657  C CB  . ARG A 1 488 ? 124.221 150.890 103.668 1.00 121.96 ? 508 ARG A CB  1 
ATOM   3658  C CG  . ARG A 1 488 ? 124.559 152.359 103.895 1.00 127.52 ? 508 ARG A CG  1 
ATOM   3659  C CD  . ARG A 1 488 ? 125.107 152.640 105.285 1.00 131.41 ? 508 ARG A CD  1 
ATOM   3660  N NE  . ARG A 1 488 ? 124.287 152.089 106.360 1.00 134.51 ? 508 ARG A NE  1 
ATOM   3661  C CZ  . ARG A 1 488 ? 123.027 152.432 106.618 1.00 137.71 ? 508 ARG A CZ  1 
ATOM   3662  N NH1 . ARG A 1 488 ? 122.453 153.430 105.969 1.00 137.91 ? 508 ARG A NH1 1 
ATOM   3663  N NH2 . ARG A 1 488 ? 122.349 151.790 107.555 1.00 139.15 ? 508 ARG A NH2 1 
ATOM   3664  N N   . SER A 1 489 ? 123.343 148.574 101.284 1.00 94.93  ? 509 SER A N   1 
ATOM   3665  C CA  . SER A 1 489 ? 123.195 147.154 101.049 1.00 90.13  ? 509 SER A CA  1 
ATOM   3666  C C   . SER A 1 489 ? 124.135 146.370 101.961 1.00 87.91  ? 509 SER A C   1 
ATOM   3667  O O   . SER A 1 489 ? 125.161 145.866 101.512 1.00 88.26  ? 509 SER A O   1 
ATOM   3668  C CB  . SER A 1 489 ? 123.416 146.835 99.596  1.00 89.05  ? 509 SER A CB  1 
ATOM   3669  O OG  . SER A 1 489 ? 122.309 147.247 98.821  1.00 88.69  ? 509 SER A OG  1 
ATOM   3670  N N   . VAL A 1 490 ? 123.752 146.247 103.237 1.00 85.23  ? 510 VAL A N   1 
ATOM   3671  C CA  . VAL A 1 490 ? 124.498 145.469 104.211 1.00 83.50  ? 510 VAL A CA  1 
ATOM   3672  C C   . VAL A 1 490 ? 123.553 144.433 104.812 1.00 86.07  ? 510 VAL A C   1 
ATOM   3673  O O   . VAL A 1 490 ? 122.382 144.724 105.042 1.00 86.06  ? 510 VAL A O   1 
ATOM   3674  C CB  . VAL A 1 490 ? 125.126 146.364 105.297 1.00 81.32  ? 510 VAL A CB  1 
ATOM   3675  C CG1 . VAL A 1 490 ? 126.297 147.171 104.758 1.00 80.72  ? 510 VAL A CG1 1 
ATOM   3676  C CG2 . VAL A 1 490 ? 124.103 147.281 105.954 1.00 81.30  ? 510 VAL A CG2 1 
ATOM   3677  N N   . CYS A 1 491 ? 124.075 143.223 105.050 1.00 88.93  ? 511 CYS A N   1 
ATOM   3678  C CA  . CYS A 1 491 ? 123.259 142.098 105.476 1.00 91.86  ? 511 CYS A CA  1 
ATOM   3679  C C   . CYS A 1 491 ? 123.151 142.037 106.998 1.00 97.41  ? 511 CYS A C   1 
ATOM   3680  O O   . CYS A 1 491 ? 122.332 141.291 107.526 1.00 99.02  ? 511 CYS A O   1 
ATOM   3681  C CB  . CYS A 1 491 ? 123.843 140.798 104.949 1.00 92.48  ? 511 CYS A CB  1 
ATOM   3682  S SG  . CYS A 1 491 ? 122.722 139.380 105.062 1.00 96.83  ? 511 CYS A SG  1 
ATOM   3683  N N   . SER A 1 492 ? 123.967 142.843 107.691 1.00 103.58 ? 512 SER A N   1 
ATOM   3684  C CA  . SER A 1 492 ? 123.934 142.926 109.141 1.00 108.49 ? 512 SER A CA  1 
ATOM   3685  C C   . SER A 1 492 ? 124.475 144.273 109.606 1.00 115.64 ? 512 SER A C   1 
ATOM   3686  O O   . SER A 1 492 ? 125.410 144.816 109.021 1.00 115.12 ? 512 SER A O   1 
ATOM   3687  C CB  . SER A 1 492 ? 124.701 141.793 109.762 1.00 107.59 ? 512 SER A CB  1 
ATOM   3688  O OG  . SER A 1 492 ? 123.984 140.579 109.588 1.00 106.83 ? 512 SER A OG  1 
ATOM   3689  N N   . GLU A 1 493 ? 123.880 144.790 110.687 1.00 123.94 ? 513 GLU A N   1 
ATOM   3690  C CA  . GLU A 1 493 ? 124.366 145.995 111.335 1.00 130.90 ? 513 GLU A CA  1 
ATOM   3691  C C   . GLU A 1 493 ? 125.738 145.709 111.946 1.00 130.95 ? 513 GLU A C   1 
ATOM   3692  O O   . GLU A 1 493 ? 126.029 144.584 112.354 1.00 128.34 ? 513 GLU A O   1 
ATOM   3693  C CB  . GLU A 1 493 ? 123.338 146.469 112.365 1.00 138.20 ? 513 GLU A CB  1 
ATOM   3694  C CG  . GLU A 1 493 ? 123.252 145.586 113.597 1.00 145.51 ? 513 GLU A CG  1 
ATOM   3695  C CD  . GLU A 1 493 ? 124.195 145.963 114.729 1.00 150.31 ? 513 GLU A CD  1 
ATOM   3696  O OE1 . GLU A 1 493 ? 124.708 147.102 114.726 1.00 151.04 ? 513 GLU A OE1 1 
ATOM   3697  O OE2 . GLU A 1 493 ? 124.409 145.115 115.624 1.00 151.33 ? 513 GLU A OE2 1 
ATOM   3698  N N   . PRO A 1 494 ? 126.589 146.741 112.130 1.00 135.72 ? 514 PRO A N   1 
ATOM   3699  C CA  . PRO A 1 494 ? 127.957 146.530 112.595 1.00 138.60 ? 514 PRO A CA  1 
ATOM   3700  C C   . PRO A 1 494 ? 127.913 146.194 114.082 1.00 142.15 ? 514 PRO A C   1 
ATOM   3701  O O   . PRO A 1 494 ? 127.631 147.059 114.908 1.00 142.50 ? 514 PRO A O   1 
ATOM   3702  C CB  . PRO A 1 494 ? 128.662 147.862 112.299 1.00 139.25 ? 514 PRO A CB  1 
ATOM   3703  C CG  . PRO A 1 494 ? 127.550 148.903 112.272 1.00 139.88 ? 514 PRO A CG  1 
ATOM   3704  C CD  . PRO A 1 494 ? 126.241 148.166 112.053 1.00 138.40 ? 514 PRO A CD  1 
ATOM   3705  N N   . CYS A 1 495 ? 128.198 144.927 114.401 1.00 147.92 ? 515 CYS A N   1 
ATOM   3706  C CA  . CYS A 1 495 ? 127.905 144.358 115.706 1.00 152.95 ? 515 CYS A CA  1 
ATOM   3707  C C   . CYS A 1 495 ? 129.064 144.516 116.686 1.00 163.61 ? 515 CYS A C   1 
ATOM   3708  O O   . CYS A 1 495 ? 129.007 143.940 117.762 1.00 165.88 ? 515 CYS A O   1 
ATOM   3709  C CB  . CYS A 1 495 ? 127.584 142.877 115.544 1.00 148.69 ? 515 CYS A CB  1 
ATOM   3710  S SG  . CYS A 1 495 ? 126.646 142.158 116.915 1.00 140.77 ? 515 CYS A SG  1 
ATOM   3711  N N   . GLU A 1 496 ? 130.090 145.308 116.341 1.00 175.14 ? 516 GLU A N   1 
ATOM   3712  C CA  . GLU A 1 496 ? 131.254 145.441 117.200 1.00 185.30 ? 516 GLU A CA  1 
ATOM   3713  C C   . GLU A 1 496 ? 130.995 146.522 118.246 1.00 189.32 ? 516 GLU A C   1 
ATOM   3714  O O   . GLU A 1 496 ? 131.755 147.479 118.359 1.00 191.02 ? 516 GLU A O   1 
ATOM   3715  C CB  . GLU A 1 496 ? 132.499 145.720 116.355 1.00 189.64 ? 516 GLU A CB  1 
ATOM   3716  C CG  . GLU A 1 496 ? 133.780 145.264 117.021 1.00 193.31 ? 516 GLU A CG  1 
ATOM   3717  C CD  . GLU A 1 496 ? 133.880 143.762 117.236 1.00 194.83 ? 516 GLU A CD  1 
ATOM   3718  O OE1 . GLU A 1 496 ? 133.028 143.015 116.702 1.00 192.79 ? 516 GLU A OE1 1 
ATOM   3719  O OE2 . GLU A 1 496 ? 134.802 143.342 117.953 1.00 195.66 ? 516 GLU A OE2 1 
ATOM   3720  N N   . LYS A 1 497 ? 129.927 146.331 119.031 1.00 188.69 ? 517 LYS A N   1 
ATOM   3721  C CA  . LYS A 1 497 ? 129.507 147.289 120.037 1.00 187.44 ? 517 LYS A CA  1 
ATOM   3722  C C   . LYS A 1 497 ? 129.531 146.606 121.402 1.00 179.65 ? 517 LYS A C   1 
ATOM   3723  O O   . LYS A 1 497 ? 128.503 146.113 121.865 1.00 178.14 ? 517 LYS A O   1 
ATOM   3724  C CB  . LYS A 1 497 ? 128.117 147.838 119.690 1.00 191.65 ? 517 LYS A CB  1 
ATOM   3725  C CG  . LYS A 1 497 ? 127.614 148.946 120.605 1.00 197.12 ? 517 LYS A CG  1 
ATOM   3726  C CD  . LYS A 1 497 ? 126.343 149.608 120.115 1.00 201.79 ? 517 LYS A CD  1 
ATOM   3727  C CE  . LYS A 1 497 ? 125.929 150.789 120.967 1.00 204.89 ? 517 LYS A CE  1 
ATOM   3728  N NZ  . LYS A 1 497 ? 124.731 151.468 120.417 1.00 206.51 ? 517 LYS A NZ  1 
ATOM   3729  N N   . GLY A 1 498 ? 130.712 146.591 122.034 1.00 172.23 ? 518 GLY A N   1 
ATOM   3730  C CA  . GLY A 1 498 ? 130.866 146.073 123.383 1.00 167.85 ? 518 GLY A CA  1 
ATOM   3731  C C   . GLY A 1 498 ? 131.259 144.599 123.387 1.00 164.39 ? 518 GLY A C   1 
ATOM   3732  O O   . GLY A 1 498 ? 132.195 144.203 122.694 1.00 160.74 ? 518 GLY A O   1 
ATOM   3733  N N   . GLN A 1 499 ? 130.523 143.801 124.171 1.00 163.72 ? 519 GLN A N   1 
ATOM   3734  C CA  . GLN A 1 499 ? 130.853 142.404 124.408 1.00 161.24 ? 519 GLN A CA  1 
ATOM   3735  C C   . GLN A 1 499 ? 130.334 141.503 123.289 1.00 151.49 ? 519 GLN A C   1 
ATOM   3736  O O   . GLN A 1 499 ? 130.673 140.325 123.262 1.00 150.16 ? 519 GLN A O   1 
ATOM   3737  C CB  . GLN A 1 499 ? 130.297 141.943 125.759 1.00 165.42 ? 519 GLN A CB  1 
ATOM   3738  C CG  . GLN A 1 499 ? 128.799 141.648 125.781 1.00 167.54 ? 519 GLN A CG  1 
ATOM   3739  C CD  . GLN A 1 499 ? 127.930 142.885 125.779 1.00 168.99 ? 519 GLN A CD  1 
ATOM   3740  O OE1 . GLN A 1 499 ? 128.410 144.014 125.696 1.00 170.25 ? 519 GLN A OE1 1 
ATOM   3741  N NE2 . GLN A 1 499 ? 126.627 142.675 125.869 1.00 168.64 ? 519 GLN A NE2 1 
ATOM   3742  N N   . ILE A 1 500 ? 129.479 142.032 122.405 1.00 141.23 ? 520 ILE A N   1 
ATOM   3743  C CA  . ILE A 1 500 ? 128.837 141.226 121.378 1.00 132.43 ? 520 ILE A CA  1 
ATOM   3744  C C   . ILE A 1 500 ? 129.884 140.876 120.320 1.00 124.45 ? 520 ILE A C   1 
ATOM   3745  O O   . ILE A 1 500 ? 130.685 141.726 119.928 1.00 122.45 ? 520 ILE A O   1 
ATOM   3746  C CB  . ILE A 1 500 ? 127.612 141.943 120.769 1.00 132.66 ? 520 ILE A CB  1 
ATOM   3747  C CG1 . ILE A 1 500 ? 126.920 142.911 121.735 1.00 133.67 ? 520 ILE A CG1 1 
ATOM   3748  C CG2 . ILE A 1 500 ? 126.621 140.926 120.229 1.00 131.74 ? 520 ILE A CG2 1 
ATOM   3749  C CD1 . ILE A 1 500 ? 125.935 143.835 121.066 1.00 133.11 ? 520 ILE A CD1 1 
ATOM   3750  N N   . LYS A 1 501 ? 129.883 139.609 119.884 1.00 118.50 ? 521 LYS A N   1 
ATOM   3751  C CA  . LYS A 1 501 ? 130.893 139.102 118.966 1.00 114.88 ? 521 LYS A CA  1 
ATOM   3752  C C   . LYS A 1 501 ? 130.208 138.636 117.684 1.00 117.15 ? 521 LYS A C   1 
ATOM   3753  O O   . LYS A 1 501 ? 129.057 138.204 117.719 1.00 119.03 ? 521 LYS A O   1 
ATOM   3754  C CB  . LYS A 1 501 ? 131.674 137.963 119.627 1.00 112.13 ? 521 LYS A CB  1 
ATOM   3755  C CG  . LYS A 1 501 ? 132.936 137.522 118.905 1.00 112.21 ? 521 LYS A CG  1 
ATOM   3756  C CD  . LYS A 1 501 ? 133.548 136.289 119.520 1.00 113.99 ? 521 LYS A CD  1 
ATOM   3757  C CE  . LYS A 1 501 ? 132.654 135.068 119.437 1.00 115.89 ? 521 LYS A CE  1 
ATOM   3758  N NZ  . LYS A 1 501 ? 132.259 134.778 118.038 1.00 116.42 ? 521 LYS A NZ  1 
ATOM   3759  N N   . VAL A 1 502 ? 130.937 138.693 116.559 1.00 116.26 ? 522 VAL A N   1 
ATOM   3760  C CA  . VAL A 1 502 ? 130.386 138.351 115.255 1.00 115.09 ? 522 VAL A CA  1 
ATOM   3761  C C   . VAL A 1 502 ? 130.530 136.846 115.030 1.00 111.60 ? 522 VAL A C   1 
ATOM   3762  O O   . VAL A 1 502 ? 131.647 136.333 115.003 1.00 110.16 ? 522 VAL A O   1 
ATOM   3763  C CB  . VAL A 1 502 ? 131.084 139.140 114.129 1.00 117.10 ? 522 VAL A CB  1 
ATOM   3764  C CG1 . VAL A 1 502 ? 130.619 138.671 112.762 1.00 116.89 ? 522 VAL A CG1 1 
ATOM   3765  C CG2 . VAL A 1 502 ? 130.897 140.645 114.269 1.00 118.79 ? 522 VAL A CG2 1 
ATOM   3766  N N   . ILE A 1 503 ? 129.398 136.147 114.843 1.00 111.33 ? 523 ILE A N   1 
ATOM   3767  C CA  . ILE A 1 503 ? 129.424 134.744 114.451 1.00 113.47 ? 523 ILE A CA  1 
ATOM   3768  C C   . ILE A 1 503 ? 128.841 134.605 113.043 1.00 116.84 ? 523 ILE A C   1 
ATOM   3769  O O   . ILE A 1 503 ? 127.748 135.099 112.768 1.00 116.84 ? 523 ILE A O   1 
ATOM   3770  C CB  . ILE A 1 503 ? 128.690 133.841 115.468 1.00 113.60 ? 523 ILE A CB  1 
ATOM   3771  C CG1 . ILE A 1 503 ? 127.191 134.138 115.564 1.00 113.90 ? 523 ILE A CG1 1 
ATOM   3772  C CG2 . ILE A 1 503 ? 129.350 133.904 116.836 1.00 114.43 ? 523 ILE A CG2 1 
ATOM   3773  C CD1 . ILE A 1 503 ? 126.395 133.035 116.230 1.00 113.97 ? 523 ILE A CD1 1 
ATOM   3774  N N   . ARG A 1 504 ? 129.584 133.916 112.166 1.00 119.93 ? 524 ARG A N   1 
ATOM   3775  C CA  . ARG A 1 504 ? 129.192 133.735 110.775 1.00 122.62 ? 524 ARG A CA  1 
ATOM   3776  C C   . ARG A 1 504 ? 128.500 132.382 110.631 1.00 124.86 ? 524 ARG A C   1 
ATOM   3777  O O   . ARG A 1 504 ? 129.049 131.364 111.041 1.00 124.94 ? 524 ARG A O   1 
ATOM   3778  C CB  . ARG A 1 504 ? 130.414 133.858 109.863 1.00 124.69 ? 524 ARG A CB  1 
ATOM   3779  C CG  . ARG A 1 504 ? 130.924 135.284 109.707 1.00 129.82 ? 524 ARG A CG  1 
ATOM   3780  C CD  . ARG A 1 504 ? 132.117 135.371 108.779 1.00 135.09 ? 524 ARG A CD  1 
ATOM   3781  N NE  . ARG A 1 504 ? 132.457 136.758 108.485 1.00 139.09 ? 524 ARG A NE  1 
ATOM   3782  C CZ  . ARG A 1 504 ? 133.466 137.149 107.712 1.00 141.46 ? 524 ARG A CZ  1 
ATOM   3783  N NH1 . ARG A 1 504 ? 134.398 136.288 107.341 1.00 141.31 ? 524 ARG A NH1 1 
ATOM   3784  N NH2 . ARG A 1 504 ? 133.540 138.407 107.314 1.00 141.66 ? 524 ARG A NH2 1 
ATOM   3785  N N   . LYS A 1 505 ? 127.288 132.399 110.059 1.00 128.04 ? 525 LYS A N   1 
ATOM   3786  C CA  . LYS A 1 505 ? 126.381 131.266 110.123 1.00 131.58 ? 525 LYS A CA  1 
ATOM   3787  C C   . LYS A 1 505 ? 126.545 130.358 108.907 1.00 134.60 ? 525 LYS A C   1 
ATOM   3788  O O   . LYS A 1 505 ? 125.758 129.435 108.737 1.00 135.43 ? 525 LYS A O   1 
ATOM   3789  C CB  . LYS A 1 505 ? 124.940 131.779 110.226 1.00 132.77 ? 525 LYS A CB  1 
ATOM   3790  C CG  . LYS A 1 505 ? 124.670 132.665 111.438 1.00 134.27 ? 525 LYS A CG  1 
ATOM   3791  C CD  . LYS A 1 505 ? 124.877 131.974 112.777 1.00 134.96 ? 525 LYS A CD  1 
ATOM   3792  C CE  . LYS A 1 505 ? 123.994 130.759 112.972 1.00 134.65 ? 525 LYS A CE  1 
ATOM   3793  N NZ  . LYS A 1 505 ? 124.148 130.186 114.330 1.00 133.99 ? 525 LYS A NZ  1 
ATOM   3794  N N   . GLY A 1 506 ? 127.540 130.635 108.049 1.00 137.09 ? 526 GLY A N   1 
ATOM   3795  C CA  . GLY A 1 506 ? 127.744 129.871 106.827 1.00 137.87 ? 526 GLY A CA  1 
ATOM   3796  C C   . GLY A 1 506 ? 127.029 130.480 105.620 1.00 137.28 ? 526 GLY A C   1 
ATOM   3797  O O   . GLY A 1 506 ? 127.436 130.246 104.482 1.00 135.64 ? 526 GLY A O   1 
ATOM   3798  N N   . GLU A 1 507 ? 125.969 131.257 105.883 1.00 136.01 ? 527 GLU A N   1 
ATOM   3799  C CA  . GLU A 1 507 ? 125.202 131.938 104.850 1.00 133.77 ? 527 GLU A CA  1 
ATOM   3800  C C   . GLU A 1 507 ? 126.177 132.570 103.854 1.00 126.01 ? 527 GLU A C   1 
ATOM   3801  O O   . GLU A 1 507 ? 126.260 132.152 102.700 1.00 126.97 ? 527 GLU A O   1 
ATOM   3802  C CB  . GLU A 1 507 ? 124.282 133.000 105.466 1.00 138.54 ? 527 GLU A CB  1 
ATOM   3803  C CG  . GLU A 1 507 ? 123.587 132.566 106.746 1.00 143.49 ? 527 GLU A CG  1 
ATOM   3804  C CD  . GLU A 1 507 ? 122.868 131.231 106.665 1.00 146.97 ? 527 GLU A CD  1 
ATOM   3805  O OE1 . GLU A 1 507 ? 121.962 131.102 105.816 1.00 149.21 ? 527 GLU A OE1 1 
ATOM   3806  O OE2 . GLU A 1 507 ? 123.212 130.327 107.447 1.00 146.73 ? 527 GLU A OE2 1 
ATOM   3807  N N   . VAL A 1 508 ? 126.921 133.575 104.335 1.00 115.94 ? 528 VAL A N   1 
ATOM   3808  C CA  . VAL A 1 508 ? 128.033 134.178 103.618 1.00 108.42 ? 528 VAL A CA  1 
ATOM   3809  C C   . VAL A 1 508 ? 128.834 134.978 104.646 1.00 103.66 ? 528 VAL A C   1 
ATOM   3810  O O   . VAL A 1 508 ? 128.355 135.193 105.757 1.00 103.61 ? 528 VAL A O   1 
ATOM   3811  C CB  . VAL A 1 508 ? 127.543 135.049 102.440 1.00 106.67 ? 528 VAL A CB  1 
ATOM   3812  C CG1 . VAL A 1 508 ? 126.844 136.319 102.906 1.00 106.70 ? 528 VAL A CG1 1 
ATOM   3813  C CG2 . VAL A 1 508 ? 128.663 135.382 101.466 1.00 106.45 ? 528 VAL A CG2 1 
ATOM   3814  N N   . SER A 1 509 ? 130.043 135.422 104.278 1.00 98.33  ? 529 SER A N   1 
ATOM   3815  C CA  . SER A 1 509 ? 130.917 136.170 105.172 1.00 94.94  ? 529 SER A CA  1 
ATOM   3816  C C   . SER A 1 509 ? 130.236 137.419 105.731 1.00 91.97  ? 529 SER A C   1 
ATOM   3817  O O   . SER A 1 509 ? 130.645 137.937 106.763 1.00 92.57  ? 529 SER A O   1 
ATOM   3818  C CB  . SER A 1 509 ? 132.189 136.559 104.464 1.00 96.16  ? 529 SER A CB  1 
ATOM   3819  O OG  . SER A 1 509 ? 131.924 137.467 103.404 1.00 96.90  ? 529 SER A OG  1 
ATOM   3820  N N   . CYS A 1 510 ? 129.187 137.878 105.035 1.00 90.03  ? 530 CYS A N   1 
ATOM   3821  C CA  . CYS A 1 510 ? 128.658 139.221 105.177 1.00 87.79  ? 530 CYS A CA  1 
ATOM   3822  C C   . CYS A 1 510 ? 127.283 139.221 105.853 1.00 88.51  ? 530 CYS A C   1 
ATOM   3823  O O   . CYS A 1 510 ? 126.756 140.292 106.158 1.00 89.42  ? 530 CYS A O   1 
ATOM   3824  C CB  . CYS A 1 510 ? 128.594 139.880 103.802 1.00 85.64  ? 530 CYS A CB  1 
ATOM   3825  S SG  . CYS A 1 510 ? 130.222 140.172 103.052 1.00 83.01  ? 530 CYS A SG  1 
ATOM   3826  N N   . CYS A 1 511 ? 126.714 138.026 106.089 1.00 90.10  ? 531 CYS A N   1 
ATOM   3827  C CA  . CYS A 1 511 ? 125.544 137.873 106.945 1.00 94.09  ? 531 CYS A CA  1 
ATOM   3828  C C   . CYS A 1 511 ? 125.937 137.145 108.232 1.00 97.76  ? 531 CYS A C   1 
ATOM   3829  O O   . CYS A 1 511 ? 126.217 135.946 108.210 1.00 100.10 ? 531 CYS A O   1 
ATOM   3830  C CB  . CYS A 1 511 ? 124.419 137.103 106.255 1.00 95.38  ? 531 CYS A CB  1 
ATOM   3831  S SG  . CYS A 1 511 ? 123.932 137.788 104.650 1.00 99.88  ? 531 CYS A SG  1 
ATOM   3832  N N   . TRP A 1 512 ? 125.929 137.868 109.364 1.00 99.78  ? 532 TRP A N   1 
ATOM   3833  C CA  . TRP A 1 512 ? 126.250 137.286 110.657 1.00 100.23 ? 532 TRP A CA  1 
ATOM   3834  C C   . TRP A 1 512 ? 125.098 137.509 111.637 1.00 103.17 ? 532 TRP A C   1 
ATOM   3835  O O   . TRP A 1 512 ? 124.235 138.355 111.404 1.00 104.08 ? 532 TRP A O   1 
ATOM   3836  C CB  . TRP A 1 512 ? 127.571 137.866 111.186 1.00 97.70  ? 532 TRP A CB  1 
ATOM   3837  C CG  . TRP A 1 512 ? 127.555 139.348 111.406 1.00 95.77  ? 532 TRP A CG  1 
ATOM   3838  C CD1 . TRP A 1 512 ? 126.818 140.031 112.330 1.00 95.66  ? 532 TRP A CD1 1 
ATOM   3839  C CD2 . TRP A 1 512 ? 128.330 140.333 110.704 1.00 96.11  ? 532 TRP A CD2 1 
ATOM   3840  N NE1 . TRP A 1 512 ? 127.069 141.373 112.240 1.00 96.55  ? 532 TRP A NE1 1 
ATOM   3841  C CE2 . TRP A 1 512 ? 127.995 141.589 111.255 1.00 96.79  ? 532 TRP A CE2 1 
ATOM   3842  C CE3 . TRP A 1 512 ? 129.275 140.276 109.675 1.00 98.06  ? 532 TRP A CE3 1 
ATOM   3843  C CZ2 . TRP A 1 512 ? 128.566 142.776 110.800 1.00 99.06  ? 532 TRP A CZ2 1 
ATOM   3844  C CZ3 . TRP A 1 512 ? 129.839 141.450 109.224 1.00 99.24  ? 532 TRP A CZ3 1 
ATOM   3845  C CH2 . TRP A 1 512 ? 129.490 142.681 109.783 1.00 99.90  ? 532 TRP A CH2 1 
ATOM   3846  N N   . THR A 1 513 ? 125.115 136.737 112.733 1.00 105.71 ? 533 THR A N   1 
ATOM   3847  C CA  . THR A 1 513 ? 124.339 137.030 113.927 1.00 108.32 ? 533 THR A CA  1 
ATOM   3848  C C   . THR A 1 513 ? 125.305 137.437 115.041 1.00 111.97 ? 533 THR A C   1 
ATOM   3849  O O   . THR A 1 513 ? 126.484 137.699 114.797 1.00 111.79 ? 533 THR A O   1 
ATOM   3850  C CB  . THR A 1 513 ? 123.440 135.846 114.311 1.00 110.15 ? 533 THR A CB  1 
ATOM   3851  O OG1 . THR A 1 513 ? 124.277 134.711 114.515 1.00 110.79 ? 533 THR A OG1 1 
ATOM   3852  C CG2 . THR A 1 513 ? 122.398 135.525 113.263 1.00 111.66 ? 533 THR A CG2 1 
ATOM   3853  N N   . CYS A 1 514 ? 124.805 137.506 116.279 1.00 118.78 ? 534 CYS A N   1 
ATOM   3854  C CA  . CYS A 1 514 ? 125.541 138.159 117.348 1.00 125.40 ? 534 CYS A CA  1 
ATOM   3855  C C   . CYS A 1 514 ? 125.331 137.436 118.675 1.00 128.42 ? 534 CYS A C   1 
ATOM   3856  O O   . CYS A 1 514 ? 124.198 137.165 119.064 1.00 129.75 ? 534 CYS A O   1 
ATOM   3857  C CB  . CYS A 1 514 ? 125.112 139.616 117.445 1.00 128.46 ? 534 CYS A CB  1 
ATOM   3858  S SG  . CYS A 1 514 ? 125.675 140.606 116.038 1.00 133.50 ? 534 CYS A SG  1 
ATOM   3859  N N   . THR A 1 515 ? 126.446 137.131 119.351 1.00 129.41 ? 535 THR A N   1 
ATOM   3860  C CA  . THR A 1 515 ? 126.416 136.513 120.667 1.00 130.64 ? 535 THR A CA  1 
ATOM   3861  C C   . THR A 1 515 ? 127.239 137.366 121.629 1.00 131.53 ? 535 THR A C   1 
ATOM   3862  O O   . THR A 1 515 ? 128.379 137.702 121.328 1.00 130.78 ? 535 THR A O   1 
ATOM   3863  C CB  . THR A 1 515 ? 126.949 135.073 120.639 1.00 129.95 ? 535 THR A CB  1 
ATOM   3864  O OG1 . THR A 1 515 ? 128.360 135.082 120.419 1.00 128.43 ? 535 THR A OG1 1 
ATOM   3865  C CG2 . THR A 1 515 ? 126.308 134.216 119.570 1.00 129.94 ? 535 THR A CG2 1 
ATOM   3866  N N   . PRO A 1 516 ? 126.711 137.720 122.822 1.00 132.40 ? 536 PRO A N   1 
ATOM   3867  C CA  . PRO A 1 516 ? 127.472 138.505 123.790 1.00 130.76 ? 536 PRO A CA  1 
ATOM   3868  C C   . PRO A 1 516 ? 128.541 137.637 124.447 1.00 127.69 ? 536 PRO A C   1 
ATOM   3869  O O   . PRO A 1 516 ? 128.256 136.518 124.868 1.00 126.73 ? 536 PRO A O   1 
ATOM   3870  C CB  . PRO A 1 516 ? 126.435 138.992 124.816 1.00 133.06 ? 536 PRO A CB  1 
ATOM   3871  C CG  . PRO A 1 516 ? 125.088 138.455 124.340 1.00 133.79 ? 536 PRO A CG  1 
ATOM   3872  C CD  . PRO A 1 516 ? 125.380 137.363 123.329 1.00 133.61 ? 536 PRO A CD  1 
ATOM   3873  N N   . CYS A 1 517 ? 129.773 138.154 124.496 1.00 126.83 ? 537 CYS A N   1 
ATOM   3874  C CA  . CYS A 1 517 ? 130.863 137.464 125.161 1.00 128.08 ? 537 CYS A CA  1 
ATOM   3875  C C   . CYS A 1 517 ? 130.835 137.833 126.643 1.00 128.58 ? 537 CYS A C   1 
ATOM   3876  O O   . CYS A 1 517 ? 130.523 138.968 127.003 1.00 129.29 ? 537 CYS A O   1 
ATOM   3877  C CB  . CYS A 1 517 ? 132.202 137.812 124.519 1.00 128.25 ? 537 CYS A CB  1 
ATOM   3878  S SG  . CYS A 1 517 ? 133.506 136.609 124.880 1.00 133.37 ? 537 CYS A SG  1 
ATOM   3879  N N   . LYS A 1 518 ? 131.214 136.886 127.504 1.00 125.55 ? 538 LYS A N   1 
ATOM   3880  C CA  . LYS A 1 518 ? 131.013 137.046 128.937 1.00 123.01 ? 538 LYS A CA  1 
ATOM   3881  C C   . LYS A 1 518 ? 132.125 137.914 129.518 1.00 120.45 ? 538 LYS A C   1 
ATOM   3882  O O   . LYS A 1 518 ? 133.105 138.216 128.838 1.00 119.57 ? 538 LYS A O   1 
ATOM   3883  C CB  . LYS A 1 518 ? 130.955 135.679 129.622 1.00 124.33 ? 538 LYS A CB  1 
ATOM   3884  C CG  . LYS A 1 518 ? 130.085 134.645 128.916 1.00 125.72 ? 538 LYS A CG  1 
ATOM   3885  C CD  . LYS A 1 518 ? 130.277 133.232 129.428 1.00 127.07 ? 538 LYS A CD  1 
ATOM   3886  C CE  . LYS A 1 518 ? 131.565 132.579 128.974 1.00 127.54 ? 538 LYS A CE  1 
ATOM   3887  N NZ  . LYS A 1 518 ? 131.558 132.294 127.518 1.00 127.75 ? 538 LYS A NZ  1 
ATOM   3888  N N   . GLU A 1 519 ? 131.967 138.283 130.793 1.00 117.60 ? 539 GLU A N   1 
ATOM   3889  C CA  . GLU A 1 519 ? 132.791 139.309 131.418 1.00 114.60 ? 539 GLU A CA  1 
ATOM   3890  C C   . GLU A 1 519 ? 134.200 138.777 131.683 1.00 106.76 ? 539 GLU A C   1 
ATOM   3891  O O   . GLU A 1 519 ? 135.153 139.549 131.737 1.00 105.42 ? 539 GLU A O   1 
ATOM   3892  C CB  . GLU A 1 519 ? 132.181 139.809 132.731 1.00 117.63 ? 539 GLU A CB  1 
ATOM   3893  C CG  . GLU A 1 519 ? 130.723 140.217 132.645 1.00 120.66 ? 539 GLU A CG  1 
ATOM   3894  C CD  . GLU A 1 519 ? 129.761 139.059 132.841 1.00 123.38 ? 539 GLU A CD  1 
ATOM   3895  O OE1 . GLU A 1 519 ? 129.709 138.177 131.960 1.00 123.97 ? 539 GLU A OE1 1 
ATOM   3896  O OE2 . GLU A 1 519 ? 129.086 139.028 133.890 1.00 125.12 ? 539 GLU A OE2 1 
ATOM   3897  N N   . ASN A 1 520 ? 134.326 137.457 131.866 1.00 101.42 ? 540 ASN A N   1 
ATOM   3898  C CA  . ASN A 1 520 ? 135.619 136.827 132.079 1.00 99.91  ? 540 ASN A CA  1 
ATOM   3899  C C   . ASN A 1 520 ? 136.520 137.039 130.863 1.00 101.13 ? 540 ASN A C   1 
ATOM   3900  O O   . ASN A 1 520 ? 137.724 137.240 131.007 1.00 100.15 ? 540 ASN A O   1 
ATOM   3901  C CB  . ASN A 1 520 ? 135.465 135.334 132.377 1.00 100.64 ? 540 ASN A CB  1 
ATOM   3902  C CG  . ASN A 1 520 ? 136.773 134.657 132.731 1.00 101.19 ? 540 ASN A CG  1 
ATOM   3903  O OD1 . ASN A 1 520 ? 137.782 135.319 132.968 1.00 100.88 ? 540 ASN A OD1 1 
ATOM   3904  N ND2 . ASN A 1 520 ? 136.762 133.337 132.767 1.00 101.66 ? 540 ASN A ND2 1 
ATOM   3905  N N   . GLU A 1 521 ? 135.921 137.000 129.664 1.00 103.92 ? 541 GLU A N   1 
ATOM   3906  C CA  . GLU A 1 521 ? 136.665 136.989 128.418 1.00 104.45 ? 541 GLU A CA  1 
ATOM   3907  C C   . GLU A 1 521 ? 136.759 138.389 127.818 1.00 104.24 ? 541 GLU A C   1 
ATOM   3908  O O   . GLU A 1 521 ? 136.060 139.310 128.231 1.00 103.81 ? 541 GLU A O   1 
ATOM   3909  C CB  . GLU A 1 521 ? 135.980 136.067 127.411 1.00 105.89 ? 541 GLU A CB  1 
ATOM   3910  C CG  . GLU A 1 521 ? 135.668 134.682 127.950 1.00 107.19 ? 541 GLU A CG  1 
ATOM   3911  C CD  . GLU A 1 521 ? 134.329 134.143 127.484 1.00 108.86 ? 541 GLU A CD  1 
ATOM   3912  O OE1 . GLU A 1 521 ? 133.326 134.864 127.653 1.00 108.51 ? 541 GLU A OE1 1 
ATOM   3913  O OE2 . GLU A 1 521 ? 134.291 133.016 126.949 1.00 109.42 ? 541 GLU A OE2 1 
ATOM   3914  N N   . TYR A 1 522 ? 137.626 138.503 126.808 1.00 105.32 ? 542 TYR A N   1 
ATOM   3915  C CA  . TYR A 1 522 ? 137.799 139.719 126.029 1.00 106.82 ? 542 TYR A CA  1 
ATOM   3916  C C   . TYR A 1 522 ? 137.851 139.346 124.550 1.00 110.73 ? 542 TYR A C   1 
ATOM   3917  O O   . TYR A 1 522 ? 138.267 138.240 124.196 1.00 112.12 ? 542 TYR A O   1 
ATOM   3918  C CB  . TYR A 1 522 ? 139.079 140.464 126.424 1.00 104.67 ? 542 TYR A CB  1 
ATOM   3919  C CG  . TYR A 1 522 ? 140.353 139.788 125.983 1.00 103.10 ? 542 TYR A CG  1 
ATOM   3920  C CD1 . TYR A 1 522 ? 140.709 138.548 126.485 1.00 103.12 ? 542 TYR A CD1 1 
ATOM   3921  C CD2 . TYR A 1 522 ? 141.188 140.361 125.039 1.00 103.82 ? 542 TYR A CD2 1 
ATOM   3922  C CE1 . TYR A 1 522 ? 141.869 137.906 126.084 1.00 104.14 ? 542 TYR A CE1 1 
ATOM   3923  C CE2 . TYR A 1 522 ? 142.348 139.730 124.618 1.00 104.59 ? 542 TYR A CE2 1 
ATOM   3924  C CZ  . TYR A 1 522 ? 142.693 138.499 125.145 1.00 104.30 ? 542 TYR A CZ  1 
ATOM   3925  O OH  . TYR A 1 522 ? 143.840 137.861 124.743 1.00 104.01 ? 542 TYR A OH  1 
ATOM   3926  N N   . VAL A 1 523 ? 137.414 140.293 123.713 1.00 111.44 ? 543 VAL A N   1 
ATOM   3927  C CA  . VAL A 1 523 ? 137.502 140.174 122.269 1.00 111.18 ? 543 VAL A CA  1 
ATOM   3928  C C   . VAL A 1 523 ? 138.836 140.777 121.833 1.00 113.44 ? 543 VAL A C   1 
ATOM   3929  O O   . VAL A 1 523 ? 139.171 141.897 122.211 1.00 115.26 ? 543 VAL A O   1 
ATOM   3930  C CB  . VAL A 1 523 ? 136.299 140.842 121.566 1.00 110.21 ? 543 VAL A CB  1 
ATOM   3931  C CG1 . VAL A 1 523 ? 136.333 142.364 121.625 1.00 109.64 ? 543 VAL A CG1 1 
ATOM   3932  C CG2 . VAL A 1 523 ? 136.171 140.374 120.125 1.00 110.97 ? 543 VAL A CG2 1 
ATOM   3933  N N   . PHE A 1 524 ? 139.601 140.011 121.049 1.00 116.48 ? 544 PHE A N   1 
ATOM   3934  C CA  . PHE A 1 524 ? 140.917 140.416 120.577 1.00 120.73 ? 544 PHE A CA  1 
ATOM   3935  C C   . PHE A 1 524 ? 140.895 140.516 119.052 1.00 123.51 ? 544 PHE A C   1 
ATOM   3936  O O   . PHE A 1 524 ? 141.277 141.540 118.490 1.00 123.40 ? 544 PHE A O   1 
ATOM   3937  C CB  . PHE A 1 524 ? 142.002 139.450 121.070 1.00 121.63 ? 544 PHE A CB  1 
ATOM   3938  C CG  . PHE A 1 524 ? 141.895 138.035 120.559 1.00 122.54 ? 544 PHE A CG  1 
ATOM   3939  C CD1 . PHE A 1 524 ? 140.848 137.214 120.950 1.00 123.89 ? 544 PHE A CD1 1 
ATOM   3940  C CD2 . PHE A 1 524 ? 142.825 137.536 119.660 1.00 121.86 ? 544 PHE A CD2 1 
ATOM   3941  C CE1 . PHE A 1 524 ? 140.745 135.918 120.469 1.00 124.28 ? 544 PHE A CE1 1 
ATOM   3942  C CE2 . PHE A 1 524 ? 142.722 136.239 119.182 1.00 122.53 ? 544 PHE A CE2 1 
ATOM   3943  C CZ  . PHE A 1 524 ? 141.686 135.430 119.590 1.00 123.39 ? 544 PHE A CZ  1 
ATOM   3944  N N   . ASP A 1 525 ? 140.451 139.431 118.399 1.00 125.58 ? 545 ASP A N   1 
ATOM   3945  C CA  . ASP A 1 525 ? 140.130 139.428 116.982 1.00 126.92 ? 545 ASP A CA  1 
ATOM   3946  C C   . ASP A 1 525 ? 138.639 139.138 116.844 1.00 123.86 ? 545 ASP A C   1 
ATOM   3947  O O   . ASP A 1 525 ? 138.070 138.462 117.689 1.00 123.30 ? 545 ASP A O   1 
ATOM   3948  C CB  . ASP A 1 525 ? 140.980 138.396 116.240 1.00 130.98 ? 545 ASP A CB  1 
ATOM   3949  C CG  . ASP A 1 525 ? 140.551 138.157 114.802 1.00 134.77 ? 545 ASP A CG  1 
ATOM   3950  O OD1 . ASP A 1 525 ? 140.473 139.142 114.040 1.00 136.40 ? 545 ASP A OD1 1 
ATOM   3951  O OD2 . ASP A 1 525 ? 140.281 136.991 114.464 1.00 135.92 ? 545 ASP A OD2 1 
ATOM   3952  N N   . GLU A 1 526 ? 138.015 139.640 115.773 1.00 122.25 ? 546 GLU A N   1 
ATOM   3953  C CA  . GLU A 1 526 ? 136.600 139.390 115.542 1.00 122.13 ? 546 GLU A CA  1 
ATOM   3954  C C   . GLU A 1 526 ? 136.369 137.883 115.462 1.00 120.65 ? 546 GLU A C   1 
ATOM   3955  O O   . GLU A 1 526 ? 137.311 137.121 115.260 1.00 120.96 ? 546 GLU A O   1 
ATOM   3956  C CB  . GLU A 1 526 ? 136.119 140.077 114.265 1.00 126.72 ? 546 GLU A CB  1 
ATOM   3957  C CG  . GLU A 1 526 ? 136.168 141.592 114.328 1.00 132.37 ? 546 GLU A CG  1 
ATOM   3958  C CD  . GLU A 1 526 ? 135.518 142.306 113.153 1.00 135.40 ? 546 GLU A CD  1 
ATOM   3959  O OE1 . GLU A 1 526 ? 134.955 141.618 112.274 1.00 136.36 ? 546 GLU A OE1 1 
ATOM   3960  O OE2 . GLU A 1 526 ? 135.577 143.552 113.117 1.00 135.56 ? 546 GLU A OE2 1 
ATOM   3961  N N   . TYR A 1 527 ? 135.110 137.463 115.651 1.00 121.07 ? 547 TYR A N   1 
ATOM   3962  C CA  . TYR A 1 527 ? 134.700 136.069 115.529 1.00 122.92 ? 547 TYR A CA  1 
ATOM   3963  C C   . TYR A 1 527 ? 135.233 135.215 116.685 1.00 122.29 ? 547 TYR A C   1 
ATOM   3964  O O   . TYR A 1 527 ? 134.832 134.064 116.839 1.00 122.82 ? 547 TYR A O   1 
ATOM   3965  C CB  . TYR A 1 527 ? 135.124 135.470 114.181 1.00 125.31 ? 547 TYR A CB  1 
ATOM   3966  C CG  . TYR A 1 527 ? 134.999 136.386 112.988 1.00 126.22 ? 547 TYR A CG  1 
ATOM   3967  C CD1 . TYR A 1 527 ? 133.778 136.915 112.598 1.00 126.90 ? 547 TYR A CD1 1 
ATOM   3968  C CD2 . TYR A 1 527 ? 136.119 136.743 112.255 1.00 126.39 ? 547 TYR A CD2 1 
ATOM   3969  C CE1 . TYR A 1 527 ? 133.674 137.769 111.512 1.00 126.15 ? 547 TYR A CE1 1 
ATOM   3970  C CE2 . TYR A 1 527 ? 136.031 137.589 111.160 1.00 126.47 ? 547 TYR A CE2 1 
ATOM   3971  C CZ  . TYR A 1 527 ? 134.803 138.106 110.787 1.00 126.44 ? 547 TYR A CZ  1 
ATOM   3972  O OH  . TYR A 1 527 ? 134.707 138.947 109.707 1.00 126.37 ? 547 TYR A OH  1 
ATOM   3973  N N   . THR A 1 528 ? 136.125 135.780 117.511 1.00 123.02 ? 548 THR A N   1 
ATOM   3974  C CA  . THR A 1 528 ? 136.850 135.028 118.528 1.00 124.43 ? 548 THR A CA  1 
ATOM   3975  C C   . THR A 1 528 ? 137.048 135.888 119.778 1.00 125.06 ? 548 THR A C   1 
ATOM   3976  O O   . THR A 1 528 ? 137.694 136.927 119.712 1.00 124.05 ? 548 THR A O   1 
ATOM   3977  C CB  . THR A 1 528 ? 138.220 134.576 117.998 1.00 125.19 ? 548 THR A CB  1 
ATOM   3978  O OG1 . THR A 1 528 ? 138.928 135.733 117.540 1.00 124.77 ? 548 THR A OG1 1 
ATOM   3979  C CG2 . THR A 1 528 ? 138.119 133.566 116.876 1.00 125.08 ? 548 THR A CG2 1 
ATOM   3980  N N   . CYS A 1 529 ? 136.494 135.463 120.920 1.00 125.27 ? 549 CYS A N   1 
ATOM   3981  C CA  . CYS A 1 529 ? 136.772 136.105 122.197 1.00 125.96 ? 549 CYS A CA  1 
ATOM   3982  C C   . CYS A 1 529 ? 137.191 135.025 123.189 1.00 125.43 ? 549 CYS A C   1 
ATOM   3983  O O   . CYS A 1 529 ? 136.549 133.978 123.264 1.00 123.88 ? 549 CYS A O   1 
ATOM   3984  C CB  . CYS A 1 529 ? 135.581 136.911 122.715 1.00 127.03 ? 549 CYS A CB  1 
ATOM   3985  S SG  . CYS A 1 529 ? 134.101 135.924 123.064 1.00 129.81 ? 549 CYS A SG  1 
ATOM   3986  N N   . LYS A 1 530 ? 138.271 135.281 123.940 1.00 128.37 ? 550 LYS A N   1 
ATOM   3987  C CA  . LYS A 1 530 ? 138.834 134.268 124.821 1.00 132.14 ? 550 LYS A CA  1 
ATOM   3988  C C   . LYS A 1 530 ? 138.982 134.816 126.236 1.00 133.86 ? 550 LYS A C   1 
ATOM   3989  O O   . LYS A 1 530 ? 139.017 136.019 126.443 1.00 131.89 ? 550 LYS A O   1 
ATOM   3990  C CB  . LYS A 1 530 ? 140.174 133.744 124.291 1.00 134.87 ? 550 LYS A CB  1 
ATOM   3991  C CG  . LYS A 1 530 ? 141.264 134.777 124.043 1.00 136.77 ? 550 LYS A CG  1 
ATOM   3992  C CD  . LYS A 1 530 ? 142.461 134.169 123.333 1.00 138.49 ? 550 LYS A CD  1 
ATOM   3993  C CE  . LYS A 1 530 ? 143.455 135.186 122.817 1.00 139.38 ? 550 LYS A CE  1 
ATOM   3994  N NZ  . LYS A 1 530 ? 144.487 134.552 121.964 1.00 140.89 ? 550 LYS A NZ  1 
ATOM   3995  N N   . ALA A 1 531 ? 139.065 133.892 127.199 1.00 136.95 ? 551 ALA A N   1 
ATOM   3996  C CA  . ALA A 1 531 ? 139.101 134.208 128.617 1.00 139.32 ? 551 ALA A CA  1 
ATOM   3997  C C   . ALA A 1 531 ? 140.525 134.544 129.050 1.00 142.16 ? 551 ALA A C   1 
ATOM   3998  O O   . ALA A 1 531 ? 141.486 133.939 128.576 1.00 142.02 ? 551 ALA A O   1 
ATOM   3999  C CB  . ALA A 1 531 ? 138.551 133.040 129.401 1.00 139.15 ? 551 ALA A CB  1 
ATOM   4000  N N   . CYS A 1 532 ? 140.642 135.487 129.990 1.00 145.24 ? 552 CYS A N   1 
ATOM   4001  C CA  . CYS A 1 532 ? 141.915 135.800 130.617 1.00 148.70 ? 552 CYS A CA  1 
ATOM   4002  C C   . CYS A 1 532 ? 142.214 134.783 131.716 1.00 150.12 ? 552 CYS A C   1 
ATOM   4003  O O   . CYS A 1 532 ? 141.321 134.065 132.161 1.00 149.66 ? 552 CYS A O   1 
ATOM   4004  C CB  . CYS A 1 532 ? 141.897 137.216 131.167 1.00 151.66 ? 552 CYS A CB  1 
ATOM   4005  S SG  . CYS A 1 532 ? 141.426 138.419 129.900 1.00 160.10 ? 552 CYS A SG  1 
ATOM   4006  N N   . GLN A 1 533 ? 143.477 134.752 132.159 1.00 152.44 ? 553 GLN A N   1 
ATOM   4007  C CA  . GLN A 1 533 ? 144.021 133.592 132.848 1.00 154.10 ? 553 GLN A CA  1 
ATOM   4008  C C   . GLN A 1 533 ? 143.365 133.412 134.216 1.00 150.98 ? 553 GLN A C   1 
ATOM   4009  O O   . GLN A 1 533 ? 142.534 132.519 134.374 1.00 153.17 ? 553 GLN A O   1 
ATOM   4010  C CB  . GLN A 1 533 ? 145.544 133.671 132.958 1.00 157.59 ? 553 GLN A CB  1 
ATOM   4011  C CG  . GLN A 1 533 ? 146.228 133.920 131.625 1.00 161.37 ? 553 GLN A CG  1 
ATOM   4012  C CD  . GLN A 1 533 ? 146.379 135.385 131.292 1.00 163.80 ? 553 GLN A CD  1 
ATOM   4013  O OE1 . GLN A 1 533 ? 145.930 136.267 132.021 1.00 163.08 ? 553 GLN A OE1 1 
ATOM   4014  N NE2 . GLN A 1 533 ? 147.037 135.656 130.177 1.00 164.70 ? 553 GLN A NE2 1 
ATOM   4015  N N   . LEU A 1 534 ? 143.747 134.227 135.208 1.00 144.28 ? 554 LEU A N   1 
ATOM   4016  C CA  . LEU A 1 534 ? 143.277 133.996 136.561 1.00 138.99 ? 554 LEU A CA  1 
ATOM   4017  C C   . LEU A 1 534 ? 143.189 135.289 137.360 1.00 132.61 ? 554 LEU A C   1 
ATOM   4018  O O   . LEU A 1 534 ? 142.251 135.443 138.137 1.00 133.01 ? 554 LEU A O   1 
ATOM   4019  C CB  . LEU A 1 534 ? 144.194 132.975 137.243 1.00 139.69 ? 554 LEU A CB  1 
ATOM   4020  C CG  . LEU A 1 534 ? 143.578 132.268 138.449 1.00 140.36 ? 554 LEU A CG  1 
ATOM   4021  C CD1 . LEU A 1 534 ? 142.184 131.751 138.124 1.00 139.81 ? 554 LEU A CD1 1 
ATOM   4022  C CD2 . LEU A 1 534 ? 144.468 131.125 138.915 1.00 141.69 ? 554 LEU A CD2 1 
ATOM   4023  N N   . GLY A 1 535 ? 144.168 136.189 137.195 1.00 126.03 ? 555 GLY A N   1 
ATOM   4024  C CA  . GLY A 1 535 ? 144.185 137.437 137.941 1.00 123.15 ? 555 GLY A CA  1 
ATOM   4025  C C   . GLY A 1 535 ? 144.185 138.676 137.050 1.00 120.92 ? 555 GLY A C   1 
ATOM   4026  O O   . GLY A 1 535 ? 144.889 139.634 137.348 1.00 121.27 ? 555 GLY A O   1 
ATOM   4027  N N   . SER A 1 536 ? 143.360 138.668 135.993 1.00 117.96 ? 556 SER A N   1 
ATOM   4028  C CA  . SER A 1 536 ? 143.236 139.788 135.073 1.00 116.13 ? 556 SER A CA  1 
ATOM   4029  C C   . SER A 1 536 ? 141.763 140.055 134.766 1.00 112.22 ? 556 SER A C   1 
ATOM   4030  O O   . SER A 1 536 ? 140.916 139.188 134.973 1.00 111.64 ? 556 SER A O   1 
ATOM   4031  C CB  . SER A 1 536 ? 144.006 139.515 133.812 1.00 118.07 ? 556 SER A CB  1 
ATOM   4032  O OG  . SER A 1 536 ? 145.388 139.359 134.089 1.00 118.71 ? 556 SER A OG  1 
ATOM   4033  N N   . TRP A 1 537 ? 141.479 141.262 134.259 1.00 108.84 ? 557 TRP A N   1 
ATOM   4034  C CA  . TRP A 1 537 ? 140.118 141.670 133.948 1.00 106.72 ? 557 TRP A CA  1 
ATOM   4035  C C   . TRP A 1 537 ? 140.105 142.543 132.698 1.00 111.99 ? 557 TRP A C   1 
ATOM   4036  O O   . TRP A 1 537 ? 140.992 143.379 132.524 1.00 113.75 ? 557 TRP A O   1 
ATOM   4037  C CB  . TRP A 1 537 ? 139.503 142.418 135.131 1.00 101.82 ? 557 TRP A CB  1 
ATOM   4038  C CG  . TRP A 1 537 ? 138.007 142.385 135.140 1.00 97.13  ? 557 TRP A CG  1 
ATOM   4039  C CD1 . TRP A 1 537 ? 137.146 143.430 134.969 1.00 95.80  ? 557 TRP A CD1 1 
ATOM   4040  C CD2 . TRP A 1 537 ? 137.189 141.221 135.340 1.00 94.21  ? 557 TRP A CD2 1 
ATOM   4041  N NE1 . TRP A 1 537 ? 135.849 142.994 135.058 1.00 95.72  ? 557 TRP A NE1 1 
ATOM   4042  C CE2 . TRP A 1 537 ? 135.844 141.641 135.279 1.00 94.56  ? 557 TRP A CE2 1 
ATOM   4043  C CE3 . TRP A 1 537 ? 137.465 139.867 135.558 1.00 92.13  ? 557 TRP A CE3 1 
ATOM   4044  C CZ2 . TRP A 1 537 ? 134.781 140.752 135.453 1.00 93.01  ? 557 TRP A CZ2 1 
ATOM   4045  C CZ3 . TRP A 1 537 ? 136.418 138.988 135.725 1.00 91.86  ? 557 TRP A CZ3 1 
ATOM   4046  C CH2 . TRP A 1 537 ? 135.096 139.425 135.649 1.00 92.44  ? 557 TRP A CH2 1 
ATOM   4047  N N   . PRO A 1 538 ? 139.113 142.372 131.792 1.00 116.62 ? 558 PRO A N   1 
ATOM   4048  C CA  . PRO A 1 538 ? 139.065 143.157 130.558 1.00 120.52 ? 558 PRO A CA  1 
ATOM   4049  C C   . PRO A 1 538 ? 138.864 144.646 130.822 1.00 126.51 ? 558 PRO A C   1 
ATOM   4050  O O   . PRO A 1 538 ? 138.198 145.026 131.783 1.00 127.64 ? 558 PRO A O   1 
ATOM   4051  C CB  . PRO A 1 538 ? 137.873 142.573 129.787 1.00 119.02 ? 558 PRO A CB  1 
ATOM   4052  C CG  . PRO A 1 538 ? 137.020 141.936 130.855 1.00 117.78 ? 558 PRO A CG  1 
ATOM   4053  C CD  . PRO A 1 538 ? 138.009 141.400 131.869 1.00 116.65 ? 558 PRO A CD  1 
ATOM   4054  N N   . THR A 1 539 ? 139.460 145.472 129.952 1.00 133.55 ? 559 THR A N   1 
ATOM   4055  C CA  . THR A 1 539 ? 139.362 146.922 130.032 1.00 141.53 ? 559 THR A CA  1 
ATOM   4056  C C   . THR A 1 539 ? 137.964 147.357 129.589 1.00 148.29 ? 559 THR A C   1 
ATOM   4057  O O   . THR A 1 539 ? 137.228 146.571 128.995 1.00 149.12 ? 559 THR A O   1 
ATOM   4058  C CB  . THR A 1 539 ? 140.485 147.562 129.200 1.00 143.82 ? 559 THR A CB  1 
ATOM   4059  O OG1 . THR A 1 539 ? 141.737 147.124 129.729 1.00 144.58 ? 559 THR A OG1 1 
ATOM   4060  C CG2 . THR A 1 539 ? 140.456 149.075 129.177 1.00 144.66 ? 559 THR A CG2 1 
ATOM   4061  N N   . ASP A 1 540 ? 137.595 148.605 129.903 1.00 156.20 ? 560 ASP A N   1 
ATOM   4062  C CA  . ASP A 1 540 ? 136.286 149.142 129.557 1.00 163.07 ? 560 ASP A CA  1 
ATOM   4063  C C   . ASP A 1 540 ? 136.040 149.058 128.048 1.00 162.61 ? 560 ASP A C   1 
ATOM   4064  O O   . ASP A 1 540 ? 134.907 148.855 127.623 1.00 162.51 ? 560 ASP A O   1 
ATOM   4065  C CB  . ASP A 1 540 ? 136.125 150.580 130.056 1.00 169.46 ? 560 ASP A CB  1 
ATOM   4066  C CG  . ASP A 1 540 ? 136.180 150.706 131.569 1.00 174.23 ? 560 ASP A CG  1 
ATOM   4067  O OD1 . ASP A 1 540 ? 135.320 150.098 132.240 1.00 175.42 ? 560 ASP A OD1 1 
ATOM   4068  O OD2 . ASP A 1 540 ? 137.089 151.400 132.065 1.00 176.08 ? 560 ASP A OD2 1 
ATOM   4069  N N   . ASP A 1 541 ? 137.102 149.213 127.251 1.00 161.79 ? 561 ASP A N   1 
ATOM   4070  C CA  . ASP A 1 541 ? 137.024 149.044 125.806 1.00 161.65 ? 561 ASP A CA  1 
ATOM   4071  C C   . ASP A 1 541 ? 136.809 147.575 125.430 1.00 156.31 ? 561 ASP A C   1 
ATOM   4072  O O   . ASP A 1 541 ? 136.526 147.287 124.270 1.00 154.30 ? 561 ASP A O   1 
ATOM   4073  C CB  . ASP A 1 541 ? 138.264 149.603 125.099 1.00 165.60 ? 561 ASP A CB  1 
ATOM   4074  C CG  . ASP A 1 541 ? 139.582 149.103 125.668 1.00 167.42 ? 561 ASP A CG  1 
ATOM   4075  O OD1 . ASP A 1 541 ? 139.603 147.949 126.134 1.00 165.91 ? 561 ASP A OD1 1 
ATOM   4076  O OD2 . ASP A 1 541 ? 140.576 149.862 125.626 1.00 167.89 ? 561 ASP A OD2 1 
ATOM   4077  N N   . LEU A 1 542 ? 137.011 146.657 126.387 1.00 152.51 ? 562 LEU A N   1 
ATOM   4078  C CA  . LEU A 1 542 ? 136.765 145.229 126.213 1.00 150.57 ? 562 LEU A CA  1 
ATOM   4079  C C   . LEU A 1 542 ? 137.715 144.614 125.181 1.00 148.61 ? 562 LEU A C   1 
ATOM   4080  O O   . LEU A 1 542 ? 137.401 143.578 124.596 1.00 146.61 ? 562 LEU A O   1 
ATOM   4081  C CB  . LEU A 1 542 ? 135.293 144.992 125.844 1.00 149.94 ? 562 LEU A CB  1 
ATOM   4082  C CG  . LEU A 1 542 ? 134.378 144.611 127.007 1.00 149.47 ? 562 LEU A CG  1 
ATOM   4083  C CD1 . LEU A 1 542 ? 134.237 145.753 127.998 1.00 149.39 ? 562 LEU A CD1 1 
ATOM   4084  C CD2 . LEU A 1 542 ? 133.013 144.188 126.498 1.00 149.00 ? 562 LEU A CD2 1 
ATOM   4085  N N   . THR A 1 543 ? 138.888 145.230 124.988 1.00 147.88 ? 563 THR A N   1 
ATOM   4086  C CA  . THR A 1 543 ? 139.969 144.629 124.222 1.00 148.55 ? 563 THR A CA  1 
ATOM   4087  C C   . THR A 1 543 ? 141.210 144.601 125.113 1.00 149.79 ? 563 THR A C   1 
ATOM   4088  O O   . THR A 1 543 ? 141.604 145.622 125.669 1.00 150.10 ? 563 THR A O   1 
ATOM   4089  C CB  . THR A 1 543 ? 140.194 145.356 122.886 1.00 149.60 ? 563 THR A CB  1 
ATOM   4090  O OG1 . THR A 1 543 ? 141.215 144.668 122.160 1.00 149.13 ? 563 THR A OG1 1 
ATOM   4091  C CG2 . THR A 1 543 ? 140.578 146.812 123.044 1.00 149.95 ? 563 THR A CG2 1 
ATOM   4092  N N   . GLY A 1 544 ? 141.815 143.418 125.249 1.00 150.77 ? 564 GLY A N   1 
ATOM   4093  C CA  . GLY A 1 544 ? 142.913 143.210 126.182 1.00 152.81 ? 564 GLY A CA  1 
ATOM   4094  C C   . GLY A 1 544 ? 142.445 143.296 127.632 1.00 154.14 ? 564 GLY A C   1 
ATOM   4095  O O   . GLY A 1 544 ? 141.581 144.109 127.958 1.00 154.78 ? 564 GLY A O   1 
ATOM   4096  N N   . CYS A 1 545 ? 143.015 142.450 128.501 1.00 155.25 ? 565 CYS A N   1 
ATOM   4097  C CA  . CYS A 1 545 ? 142.721 142.524 129.921 1.00 157.52 ? 565 CYS A CA  1 
ATOM   4098  C C   . CYS A 1 545 ? 143.944 142.988 130.699 1.00 159.52 ? 565 CYS A C   1 
ATOM   4099  O O   . CYS A 1 545 ? 145.057 142.516 130.472 1.00 160.17 ? 565 CYS A O   1 
ATOM   4100  C CB  . CYS A 1 545 ? 142.192 141.214 130.498 1.00 158.98 ? 565 CYS A CB  1 
ATOM   4101  S SG  . CYS A 1 545 ? 142.983 139.720 129.851 1.00 164.84 ? 565 CYS A SG  1 
ATOM   4102  N N   . ASP A 1 546 ? 143.690 143.891 131.655 1.00 158.97 ? 566 ASP A N   1 
ATOM   4103  C CA  . ASP A 1 546 ? 144.729 144.457 132.498 1.00 158.12 ? 566 ASP A CA  1 
ATOM   4104  C C   . ASP A 1 546 ? 144.713 143.772 133.863 1.00 154.44 ? 566 ASP A C   1 
ATOM   4105  O O   . ASP A 1 546 ? 143.875 142.910 134.129 1.00 151.95 ? 566 ASP A O   1 
ATOM   4106  C CB  . ASP A 1 546 ? 144.556 145.968 132.662 1.00 160.03 ? 566 ASP A CB  1 
ATOM   4107  C CG  . ASP A 1 546 ? 143.313 146.352 133.447 1.00 161.82 ? 566 ASP A CG  1 
ATOM   4108  O OD1 . ASP A 1 546 ? 142.240 146.443 132.819 1.00 162.16 ? 566 ASP A OD1 1 
ATOM   4109  O OD2 . ASP A 1 546 ? 143.422 146.532 134.679 1.00 161.66 ? 566 ASP A OD2 1 
ATOM   4110  N N   . LEU A 1 547 ? 145.663 144.164 134.719 1.00 152.02 ? 567 LEU A N   1 
ATOM   4111  C CA  . LEU A 1 547 ? 145.807 143.555 136.033 1.00 150.87 ? 567 LEU A CA  1 
ATOM   4112  C C   . LEU A 1 547 ? 144.795 144.164 136.997 1.00 147.84 ? 567 LEU A C   1 
ATOM   4113  O O   . LEU A 1 547 ? 144.719 145.381 137.154 1.00 146.48 ? 567 LEU A O   1 
ATOM   4114  C CB  . LEU A 1 547 ? 147.239 143.738 136.544 1.00 152.20 ? 567 LEU A CB  1 
ATOM   4115  C CG  . LEU A 1 547 ? 148.179 142.559 136.303 1.00 153.96 ? 567 LEU A CG  1 
ATOM   4116  C CD1 . LEU A 1 547 ? 149.569 142.854 136.845 1.00 155.05 ? 567 LEU A CD1 1 
ATOM   4117  C CD2 . LEU A 1 547 ? 147.623 141.292 136.935 1.00 153.81 ? 567 LEU A CD2 1 
ATOM   4118  N N   . ILE A 1 548 ? 143.985 143.294 137.606 1.00 143.06 ? 568 ILE A N   1 
ATOM   4119  C CA  . ILE A 1 548 ? 143.001 143.711 138.593 1.00 138.22 ? 568 ILE A CA  1 
ATOM   4120  C C   . ILE A 1 548 ? 143.746 144.166 139.844 1.00 136.68 ? 568 ILE A C   1 
ATOM   4121  O O   . ILE A 1 548 ? 144.686 143.497 140.265 1.00 134.36 ? 568 ILE A O   1 
ATOM   4122  C CB  . ILE A 1 548 ? 141.993 142.580 138.887 1.00 135.87 ? 568 ILE A CB  1 
ATOM   4123  C CG1 . ILE A 1 548 ? 140.954 143.000 139.932 1.00 135.86 ? 568 ILE A CG1 1 
ATOM   4124  C CG2 . ILE A 1 548 ? 142.692 141.279 139.265 1.00 133.62 ? 568 ILE A CG2 1 
ATOM   4125  C CD1 . ILE A 1 548 ? 139.858 143.886 139.382 1.00 136.13 ? 568 ILE A CD1 1 
ATOM   4126  N N   . PRO A 1 549 ? 143.380 145.319 140.454 1.00 138.10 ? 569 PRO A N   1 
ATOM   4127  C CA  . PRO A 1 549 ? 144.020 145.775 141.688 1.00 137.89 ? 569 PRO A CA  1 
ATOM   4128  C C   . PRO A 1 549 ? 143.847 144.768 142.820 1.00 135.41 ? 569 PRO A C   1 
ATOM   4129  O O   . PRO A 1 549 ? 142.813 144.113 142.922 1.00 136.10 ? 569 PRO A O   1 
ATOM   4130  C CB  . PRO A 1 549 ? 143.310 147.095 142.028 1.00 140.09 ? 569 PRO A CB  1 
ATOM   4131  C CG  . PRO A 1 549 ? 142.711 147.549 140.714 1.00 141.24 ? 569 PRO A CG  1 
ATOM   4132  C CD  . PRO A 1 549 ? 142.367 146.272 139.977 1.00 140.20 ? 569 PRO A CD  1 
ATOM   4133  N N   . VAL A 1 550 ? 144.882 144.654 143.656 1.00 131.96 ? 570 VAL A N   1 
ATOM   4134  C CA  . VAL A 1 550 ? 144.932 143.634 144.687 1.00 128.97 ? 570 VAL A CA  1 
ATOM   4135  C C   . VAL A 1 550 ? 144.430 144.252 145.988 1.00 129.77 ? 570 VAL A C   1 
ATOM   4136  O O   . VAL A 1 550 ? 144.873 145.330 146.379 1.00 128.91 ? 570 VAL A O   1 
ATOM   4137  C CB  . VAL A 1 550 ? 146.356 143.068 144.839 1.00 125.92 ? 570 VAL A CB  1 
ATOM   4138  C CG1 . VAL A 1 550 ? 146.375 141.852 145.748 1.00 124.19 ? 570 VAL A CG1 1 
ATOM   4139  C CG2 . VAL A 1 550 ? 146.986 142.732 143.495 1.00 126.06 ? 570 VAL A CG2 1 
ATOM   4140  N N   . GLN A 1 551 ? 143.491 143.557 146.641 1.00 131.86 ? 571 GLN A N   1 
ATOM   4141  C CA  . GLN A 1 551 ? 142.926 143.995 147.907 1.00 133.34 ? 571 GLN A CA  1 
ATOM   4142  C C   . GLN A 1 551 ? 143.576 143.186 149.029 1.00 131.07 ? 571 GLN A C   1 
ATOM   4143  O O   . GLN A 1 551 ? 143.935 142.025 148.836 1.00 127.47 ? 571 GLN A O   1 
ATOM   4144  C CB  . GLN A 1 551 ? 141.406 143.813 147.880 1.00 135.02 ? 571 GLN A CB  1 
ATOM   4145  C CG  . GLN A 1 551 ? 140.638 144.861 148.674 1.00 136.63 ? 571 GLN A CG  1 
ATOM   4146  C CD  . GLN A 1 551 ? 139.142 144.713 148.537 1.00 139.95 ? 571 GLN A CD  1 
ATOM   4147  O OE1 . GLN A 1 551 ? 138.642 143.801 147.881 1.00 140.01 ? 571 GLN A OE1 1 
ATOM   4148  N NE2 . GLN A 1 551 ? 138.407 145.618 149.163 1.00 141.60 ? 571 GLN A NE2 1 
ATOM   4149  N N   . TYR A 1 552 ? 143.675 143.802 150.211 1.00 130.59 ? 572 TYR A N   1 
ATOM   4150  C CA  . TYR A 1 552 ? 144.358 143.208 151.350 1.00 129.71 ? 572 TYR A CA  1 
ATOM   4151  C C   . TYR A 1 552 ? 143.695 143.689 152.639 1.00 129.26 ? 572 TYR A C   1 
ATOM   4152  O O   . TYR A 1 552 ? 142.554 144.135 152.606 1.00 130.03 ? 572 TYR A O   1 
ATOM   4153  C CB  . TYR A 1 552 ? 145.850 143.529 151.263 1.00 129.86 ? 572 TYR A CB  1 
ATOM   4154  C CG  . TYR A 1 552 ? 146.155 144.970 150.947 1.00 132.84 ? 572 TYR A CG  1 
ATOM   4155  C CD1 . TYR A 1 552 ? 145.980 145.973 151.888 1.00 134.87 ? 572 TYR A CD1 1 
ATOM   4156  C CD2 . TYR A 1 552 ? 146.583 145.336 149.683 1.00 134.35 ? 572 TYR A CD2 1 
ATOM   4157  C CE1 . TYR A 1 552 ? 146.246 147.300 151.589 1.00 135.21 ? 572 TYR A CE1 1 
ATOM   4158  C CE2 . TYR A 1 552 ? 146.860 146.657 149.367 1.00 135.65 ? 572 TYR A CE2 1 
ATOM   4159  C CZ  . TYR A 1 552 ? 146.694 147.642 150.325 1.00 135.80 ? 572 TYR A CZ  1 
ATOM   4160  O OH  . TYR A 1 552 ? 146.961 148.955 150.016 1.00 136.44 ? 572 TYR A OH  1 
ATOM   4161  N N   . LEU A 1 553 ? 144.408 143.603 153.770 1.00 127.56 ? 573 LEU A N   1 
ATOM   4162  C CA  . LEU A 1 553 ? 143.784 143.680 155.078 1.00 126.72 ? 573 LEU A CA  1 
ATOM   4163  C C   . LEU A 1 553 ? 143.297 145.086 155.425 1.00 128.42 ? 573 LEU A C   1 
ATOM   4164  O O   . LEU A 1 553 ? 142.500 145.213 156.342 1.00 130.06 ? 573 LEU A O   1 
ATOM   4165  C CB  . LEU A 1 553 ? 144.766 143.144 156.127 1.00 126.10 ? 573 LEU A CB  1 
ATOM   4166  C CG  . LEU A 1 553 ? 144.699 141.637 156.374 1.00 127.36 ? 573 LEU A CG  1 
ATOM   4167  C CD1 . LEU A 1 553 ? 143.256 141.184 156.568 1.00 127.80 ? 573 LEU A CD1 1 
ATOM   4168  C CD2 . LEU A 1 553 ? 145.360 140.861 155.244 1.00 127.07 ? 573 LEU A CD2 1 
ATOM   4169  N N   . ARG A 1 554 ? 143.772 146.122 154.719 1.00 130.81 ? 574 ARG A N   1 
ATOM   4170  C CA  . ARG A 1 554 ? 143.153 147.440 154.752 1.00 134.08 ? 574 ARG A CA  1 
ATOM   4171  C C   . ARG A 1 554 ? 143.159 148.031 156.163 1.00 132.99 ? 574 ARG A C   1 
ATOM   4172  O O   . ARG A 1 554 ? 142.157 147.956 156.876 1.00 132.09 ? 574 ARG A O   1 
ATOM   4173  C CB  . ARG A 1 554 ? 141.701 147.392 154.256 1.00 137.12 ? 574 ARG A CB  1 
ATOM   4174  C CG  . ARG A 1 554 ? 141.518 147.098 152.772 1.00 140.17 ? 574 ARG A CG  1 
ATOM   4175  C CD  . ARG A 1 554 ? 142.535 147.729 151.837 1.00 142.17 ? 574 ARG A CD  1 
ATOM   4176  N NE  . ARG A 1 554 ? 142.944 149.077 152.213 1.00 143.62 ? 574 ARG A NE  1 
ATOM   4177  C CZ  . ARG A 1 554 ? 143.847 149.805 151.565 1.00 144.50 ? 574 ARG A CZ  1 
ATOM   4178  N NH1 . ARG A 1 554 ? 144.262 149.443 150.363 1.00 143.03 ? 574 ARG A NH1 1 
ATOM   4179  N NH2 . ARG A 1 554 ? 144.294 150.930 152.099 1.00 145.14 ? 574 ARG A NH2 1 
ATOM   4180  N N   . TRP A 1 555 ? 144.270 148.685 156.528 1.00 130.91 ? 575 TRP A N   1 
ATOM   4181  C CA  . TRP A 1 555 ? 144.443 149.342 157.820 1.00 128.81 ? 575 TRP A CA  1 
ATOM   4182  C C   . TRP A 1 555 ? 143.219 150.171 158.220 1.00 130.17 ? 575 TRP A C   1 
ATOM   4183  O O   . TRP A 1 555 ? 142.952 150.337 159.408 1.00 128.80 ? 575 TRP A O   1 
ATOM   4184  C CB  . TRP A 1 555 ? 145.705 150.219 157.813 1.00 126.15 ? 575 TRP A CB  1 
ATOM   4185  C CG  . TRP A 1 555 ? 146.956 149.567 158.321 1.00 123.98 ? 575 TRP A CG  1 
ATOM   4186  C CD1 . TRP A 1 555 ? 148.046 149.187 157.592 1.00 122.76 ? 575 TRP A CD1 1 
ATOM   4187  C CD2 . TRP A 1 555 ? 147.277 149.281 159.694 1.00 121.78 ? 575 TRP A CD2 1 
ATOM   4188  N NE1 . TRP A 1 555 ? 149.012 148.671 158.412 1.00 120.88 ? 575 TRP A NE1 1 
ATOM   4189  C CE2 . TRP A 1 555 ? 148.562 148.696 159.706 1.00 120.86 ? 575 TRP A CE2 1 
ATOM   4190  C CE3 . TRP A 1 555 ? 146.592 149.439 160.905 1.00 121.78 ? 575 TRP A CE3 1 
ATOM   4191  C CZ2 . TRP A 1 555 ? 149.180 148.293 160.889 1.00 121.24 ? 575 TRP A CZ2 1 
ATOM   4192  C CZ3 . TRP A 1 555 ? 147.200 149.029 162.071 1.00 121.88 ? 575 TRP A CZ3 1 
ATOM   4193  C CH2 . TRP A 1 555 ? 148.476 148.463 162.061 1.00 121.92 ? 575 TRP A CH2 1 
ATOM   4194  N N   . GLY A 1 556 ? 142.509 150.720 157.227 1.00 131.60 ? 576 GLY A N   1 
ATOM   4195  C CA  . GLY A 1 556 ? 141.251 151.408 157.462 1.00 131.10 ? 576 GLY A CA  1 
ATOM   4196  C C   . GLY A 1 556 ? 140.120 150.426 157.756 1.00 134.06 ? 576 GLY A C   1 
ATOM   4197  O O   . GLY A 1 556 ? 140.358 149.374 158.339 1.00 135.40 ? 576 GLY A O   1 
ATOM   4198  N N   . ASP A 1 557 ? 138.892 150.798 157.356 1.00 139.53 ? 577 ASP A N   1 
ATOM   4199  C CA  . ASP A 1 557 ? 137.734 149.913 157.370 1.00 144.53 ? 577 ASP A CA  1 
ATOM   4200  C C   . ASP A 1 557 ? 137.274 149.674 158.809 1.00 142.38 ? 577 ASP A C   1 
ATOM   4201  O O   . ASP A 1 557 ? 138.082 149.702 159.730 1.00 141.65 ? 577 ASP A O   1 
ATOM   4202  C CB  . ASP A 1 557 ? 138.033 148.605 156.628 1.00 150.95 ? 577 ASP A CB  1 
ATOM   4203  C CG  . ASP A 1 557 ? 138.391 148.801 155.164 1.00 156.23 ? 577 ASP A CG  1 
ATOM   4204  O OD1 . ASP A 1 557 ? 138.517 149.968 154.738 1.00 158.75 ? 577 ASP A OD1 1 
ATOM   4205  O OD2 . ASP A 1 557 ? 138.532 147.784 154.459 1.00 159.06 ? 577 ASP A OD2 1 
ATOM   4206  N N   . PRO A 1 558 ? 135.973 149.400 159.059 1.00 143.81 ? 578 PRO A N   1 
ATOM   4207  C CA  . PRO A 1 558 ? 135.477 149.251 160.432 1.00 145.24 ? 578 PRO A CA  1 
ATOM   4208  C C   . PRO A 1 558 ? 136.065 148.067 161.202 1.00 143.78 ? 578 PRO A C   1 
ATOM   4209  O O   . PRO A 1 558 ? 136.445 148.203 162.367 1.00 141.84 ? 578 PRO A O   1 
ATOM   4210  C CB  . PRO A 1 558 ? 133.962 149.077 160.248 1.00 145.73 ? 578 PRO A CB  1 
ATOM   4211  C CG  . PRO A 1 558 ? 133.819 148.521 158.847 1.00 145.38 ? 578 PRO A CG  1 
ATOM   4212  C CD  . PRO A 1 558 ? 134.918 149.197 158.052 1.00 144.94 ? 578 PRO A CD  1 
ATOM   4213  N N   . GLU A 1 559 ? 136.144 146.902 160.545 1.00 142.40 ? 579 GLU A N   1 
ATOM   4214  C CA  . GLU A 1 559 ? 136.553 145.670 161.201 1.00 141.86 ? 579 GLU A CA  1 
ATOM   4215  C C   . GLU A 1 559 ? 137.989 145.783 161.721 1.00 135.43 ? 579 GLU A C   1 
ATOM   4216  O O   . GLU A 1 559 ? 138.230 145.507 162.895 1.00 134.92 ? 579 GLU A O   1 
ATOM   4217  C CB  . GLU A 1 559 ? 136.371 144.473 160.263 1.00 148.14 ? 579 GLU A CB  1 
ATOM   4218  C CG  . GLU A 1 559 ? 134.918 144.082 160.048 1.00 155.32 ? 579 GLU A CG  1 
ATOM   4219  C CD  . GLU A 1 559 ? 134.698 142.862 159.166 1.00 162.29 ? 579 GLU A CD  1 
ATOM   4220  O OE1 . GLU A 1 559 ? 135.698 142.236 158.752 1.00 165.26 ? 579 GLU A OE1 1 
ATOM   4221  O OE2 . GLU A 1 559 ? 133.524 142.540 158.892 1.00 163.24 ? 579 GLU A OE2 1 
ATOM   4222  N N   . PRO A 1 560 ? 138.993 146.178 160.902 1.00 129.78 ? 580 PRO A N   1 
ATOM   4223  C CA  . PRO A 1 560 ? 140.365 146.283 161.395 1.00 126.72 ? 580 PRO A CA  1 
ATOM   4224  C C   . PRO A 1 560 ? 140.542 147.351 162.474 1.00 124.97 ? 580 PRO A C   1 
ATOM   4225  O O   . PRO A 1 560 ? 141.317 147.154 163.408 1.00 123.62 ? 580 PRO A O   1 
ATOM   4226  C CB  . PRO A 1 560 ? 141.196 146.629 160.150 1.00 127.19 ? 580 PRO A CB  1 
ATOM   4227  C CG  . PRO A 1 560 ? 140.302 146.281 158.975 1.00 129.36 ? 580 PRO A CG  1 
ATOM   4228  C CD  . PRO A 1 560 ? 138.891 146.504 159.472 1.00 129.95 ? 580 PRO A CD  1 
ATOM   4229  N N   . ILE A 1 561 ? 139.818 148.474 162.357 1.00 124.64 ? 581 ILE A N   1 
ATOM   4230  C CA  . ILE A 1 561 ? 139.970 149.542 163.332 1.00 125.38 ? 581 ILE A CA  1 
ATOM   4231  C C   . ILE A 1 561 ? 139.390 149.078 164.666 1.00 121.45 ? 581 ILE A C   1 
ATOM   4232  O O   . ILE A 1 561 ? 139.976 149.363 165.708 1.00 121.44 ? 581 ILE A O   1 
ATOM   4233  C CB  . ILE A 1 561 ? 139.402 150.892 162.845 1.00 129.48 ? 581 ILE A CB  1 
ATOM   4234  C CG1 . ILE A 1 561 ? 137.879 150.899 162.710 1.00 132.16 ? 581 ILE A CG1 1 
ATOM   4235  C CG2 . ILE A 1 561 ? 140.094 151.331 161.562 1.00 129.62 ? 581 ILE A CG2 1 
ATOM   4236  C CD1 . ILE A 1 561 ? 137.153 151.467 163.913 1.00 132.96 ? 581 ILE A CD1 1 
ATOM   4237  N N   . ALA A 1 562 ? 138.279 148.330 164.637 1.00 118.01 ? 582 ALA A N   1 
ATOM   4238  C CA  . ALA A 1 562 ? 137.724 147.764 165.859 1.00 116.90 ? 582 ALA A CA  1 
ATOM   4239  C C   . ALA A 1 562 ? 138.715 146.776 166.478 1.00 115.12 ? 582 ALA A C   1 
ATOM   4240  O O   . ALA A 1 562 ? 138.904 146.765 167.695 1.00 114.78 ? 582 ALA A O   1 
ATOM   4241  C CB  . ALA A 1 562 ? 136.391 147.115 165.578 1.00 117.39 ? 582 ALA A CB  1 
ATOM   4242  N N   . ALA A 1 563 ? 139.351 145.957 165.629 1.00 113.06 ? 583 ALA A N   1 
ATOM   4243  C CA  . ALA A 1 563 ? 140.321 144.971 166.083 1.00 111.33 ? 583 ALA A CA  1 
ATOM   4244  C C   . ALA A 1 563 ? 141.481 145.666 166.792 1.00 109.99 ? 583 ALA A C   1 
ATOM   4245  O O   . ALA A 1 563 ? 141.896 145.226 167.862 1.00 110.06 ? 583 ALA A O   1 
ATOM   4246  C CB  . ALA A 1 563 ? 140.818 144.138 164.924 1.00 111.65 ? 583 ALA A CB  1 
ATOM   4247  N N   . VAL A 1 564 ? 141.988 146.756 166.199 1.00 109.64 ? 584 VAL A N   1 
ATOM   4248  C CA  . VAL A 1 564 ? 143.154 147.428 166.747 1.00 110.48 ? 584 VAL A CA  1 
ATOM   4249  C C   . VAL A 1 564 ? 142.755 148.171 168.020 1.00 111.87 ? 584 VAL A C   1 
ATOM   4250  O O   . VAL A 1 564 ? 143.566 148.270 168.937 1.00 112.55 ? 584 VAL A O   1 
ATOM   4251  C CB  . VAL A 1 564 ? 143.849 148.349 165.726 1.00 111.16 ? 584 VAL A CB  1 
ATOM   4252  C CG1 . VAL A 1 564 ? 144.286 147.588 164.484 1.00 112.03 ? 584 VAL A CG1 1 
ATOM   4253  C CG2 . VAL A 1 564 ? 143.004 149.549 165.349 1.00 111.36 ? 584 VAL A CG2 1 
ATOM   4254  N N   . VAL A 1 565 ? 141.515 148.672 168.086 1.00 114.78 ? 585 VAL A N   1 
ATOM   4255  C CA  . VAL A 1 565 ? 141.015 149.309 169.297 1.00 118.14 ? 585 VAL A CA  1 
ATOM   4256  C C   . VAL A 1 565 ? 141.044 148.298 170.441 1.00 119.25 ? 585 VAL A C   1 
ATOM   4257  O O   . VAL A 1 565 ? 141.520 148.611 171.534 1.00 121.14 ? 585 VAL A O   1 
ATOM   4258  C CB  . VAL A 1 565 ? 139.605 149.905 169.098 1.00 120.46 ? 585 VAL A CB  1 
ATOM   4259  C CG1 . VAL A 1 565 ? 138.847 150.058 170.410 1.00 120.47 ? 585 VAL A CG1 1 
ATOM   4260  C CG2 . VAL A 1 565 ? 139.660 151.236 168.363 1.00 121.62 ? 585 VAL A CG2 1 
ATOM   4261  N N   . PHE A 1 566 ? 140.532 147.091 170.179 1.00 118.95 ? 586 PHE A N   1 
ATOM   4262  C CA  . PHE A 1 566 ? 140.481 146.057 171.200 1.00 119.86 ? 586 PHE A CA  1 
ATOM   4263  C C   . PHE A 1 566 ? 141.897 145.651 171.610 1.00 116.67 ? 586 PHE A C   1 
ATOM   4264  O O   . PHE A 1 566 ? 142.162 145.443 172.792 1.00 117.07 ? 586 PHE A O   1 
ATOM   4265  C CB  . PHE A 1 566 ? 139.674 144.849 170.720 1.00 122.76 ? 586 PHE A CB  1 
ATOM   4266  C CG  . PHE A 1 566 ? 139.264 143.884 171.806 1.00 124.43 ? 586 PHE A CG  1 
ATOM   4267  C CD1 . PHE A 1 566 ? 139.347 144.230 173.149 1.00 127.43 ? 586 PHE A CD1 1 
ATOM   4268  C CD2 . PHE A 1 566 ? 138.793 142.621 171.482 1.00 124.06 ? 586 PHE A CD2 1 
ATOM   4269  C CE1 . PHE A 1 566 ? 138.966 143.338 174.138 1.00 129.42 ? 586 PHE A CE1 1 
ATOM   4270  C CE2 . PHE A 1 566 ? 138.417 141.730 172.476 1.00 126.39 ? 586 PHE A CE2 1 
ATOM   4271  C CZ  . PHE A 1 566 ? 138.504 142.088 173.801 1.00 129.42 ? 586 PHE A CZ  1 
ATOM   4272  N N   . ALA A 1 567 ? 142.805 145.563 170.632 1.00 115.74 ? 587 ALA A N   1 
ATOM   4273  C CA  . ALA A 1 567 ? 144.185 145.191 170.897 1.00 116.82 ? 587 ALA A CA  1 
ATOM   4274  C C   . ALA A 1 567 ? 144.857 146.234 171.785 1.00 119.26 ? 587 ALA A C   1 
ATOM   4275  O O   . ALA A 1 567 ? 145.601 145.872 172.691 1.00 119.62 ? 587 ALA A O   1 
ATOM   4276  C CB  . ALA A 1 567 ? 144.930 145.023 169.600 1.00 116.62 ? 587 ALA A CB  1 
ATOM   4277  N N   . CYS A 1 568 ? 144.591 147.521 171.524 1.00 123.09 ? 588 CYS A N   1 
ATOM   4278  C CA  . CYS A 1 568 ? 145.222 148.596 172.275 1.00 128.57 ? 588 CYS A CA  1 
ATOM   4279  C C   . CYS A 1 568 ? 144.696 148.626 173.709 1.00 130.38 ? 588 CYS A C   1 
ATOM   4280  O O   . CYS A 1 568 ? 145.470 148.834 174.637 1.00 129.93 ? 588 CYS A O   1 
ATOM   4281  C CB  . CYS A 1 568 ? 145.046 149.949 171.589 1.00 131.87 ? 588 CYS A CB  1 
ATOM   4282  S SG  . CYS A 1 568 ? 143.452 150.762 171.880 1.00 136.11 ? 588 CYS A SG  1 
ATOM   4283  N N   . LEU A 1 569 ? 143.387 148.410 173.889 1.00 132.42 ? 589 LEU A N   1 
ATOM   4284  C CA  . LEU A 1 569 ? 142.803 148.338 175.222 1.00 135.18 ? 589 LEU A CA  1 
ATOM   4285  C C   . LEU A 1 569 ? 143.419 147.166 175.988 1.00 132.51 ? 589 LEU A C   1 
ATOM   4286  O O   . LEU A 1 569 ? 143.725 147.274 177.176 1.00 130.81 ? 589 LEU A O   1 
ATOM   4287  C CB  . LEU A 1 569 ? 141.282 148.188 175.082 1.00 139.28 ? 589 LEU A CB  1 
ATOM   4288  C CG  . LEU A 1 569 ? 140.482 148.049 176.377 1.00 143.51 ? 589 LEU A CG  1 
ATOM   4289  C CD1 . LEU A 1 569 ? 140.498 149.343 177.177 1.00 145.20 ? 589 LEU A CD1 1 
ATOM   4290  C CD2 . LEU A 1 569 ? 139.053 147.626 176.077 1.00 143.93 ? 589 LEU A CD2 1 
ATOM   4291  N N   . GLY A 1 570 ? 143.601 146.043 175.285 1.00 132.64 ? 590 GLY A N   1 
ATOM   4292  C CA  . GLY A 1 570 ? 144.267 144.877 175.841 1.00 133.94 ? 590 GLY A CA  1 
ATOM   4293  C C   . GLY A 1 570 ? 145.688 145.196 176.300 1.00 135.38 ? 590 GLY A C   1 
ATOM   4294  O O   . GLY A 1 570 ? 146.098 144.795 177.385 1.00 137.53 ? 590 GLY A O   1 
ATOM   4295  N N   . LEU A 1 571 ? 146.431 145.938 175.473 1.00 134.46 ? 591 LEU A N   1 
ATOM   4296  C CA  . LEU A 1 571 ? 147.802 146.292 175.800 1.00 133.92 ? 591 LEU A CA  1 
ATOM   4297  C C   . LEU A 1 571 ? 147.840 147.175 177.043 1.00 134.23 ? 591 LEU A C   1 
ATOM   4298  O O   . LEU A 1 571 ? 148.701 146.982 177.894 1.00 133.28 ? 591 LEU A O   1 
ATOM   4299  C CB  . LEU A 1 571 ? 148.480 146.963 174.604 1.00 133.65 ? 591 LEU A CB  1 
ATOM   4300  C CG  . LEU A 1 571 ? 149.344 146.019 173.768 1.00 134.93 ? 591 LEU A CG  1 
ATOM   4301  C CD1 . LEU A 1 571 ? 149.960 146.755 172.590 1.00 135.63 ? 591 LEU A CD1 1 
ATOM   4302  C CD2 . LEU A 1 571 ? 150.429 145.389 174.635 1.00 134.98 ? 591 LEU A CD2 1 
ATOM   4303  N N   . LEU A 1 572 ? 146.914 148.134 177.142 1.00 137.56 ? 592 LEU A N   1 
ATOM   4304  C CA  . LEU A 1 572 ? 146.857 149.014 178.300 1.00 140.81 ? 592 LEU A CA  1 
ATOM   4305  C C   . LEU A 1 572 ? 146.593 148.189 179.559 1.00 136.82 ? 592 LEU A C   1 
ATOM   4306  O O   . LEU A 1 572 ? 147.231 148.403 180.585 1.00 135.80 ? 592 LEU A O   1 
ATOM   4307  C CB  . LEU A 1 572 ? 145.771 150.079 178.095 1.00 146.54 ? 592 LEU A CB  1 
ATOM   4308  C CG  . LEU A 1 572 ? 146.057 151.141 177.033 1.00 151.05 ? 592 LEU A CG  1 
ATOM   4309  C CD1 . LEU A 1 572 ? 144.932 152.163 176.980 1.00 152.43 ? 592 LEU A CD1 1 
ATOM   4310  C CD2 . LEU A 1 572 ? 147.390 151.835 177.282 1.00 152.09 ? 592 LEU A CD2 1 
ATOM   4311  N N   . ALA A 1 573 ? 145.660 147.237 179.469 1.00 134.17 ? 593 ALA A N   1 
ATOM   4312  C CA  . ALA A 1 573 ? 145.340 146.384 180.601 1.00 134.40 ? 593 ALA A CA  1 
ATOM   4313  C C   . ALA A 1 573 ? 146.565 145.560 181.003 1.00 135.34 ? 593 ALA A C   1 
ATOM   4314  O O   . ALA A 1 573 ? 146.842 145.401 182.188 1.00 136.81 ? 593 ALA A O   1 
ATOM   4315  C CB  . ALA A 1 573 ? 144.156 145.510 180.269 1.00 135.81 ? 593 ALA A CB  1 
ATOM   4316  N N   . THR A 1 574 ? 147.304 145.044 180.013 1.00 138.68 ? 594 THR A N   1 
ATOM   4317  C CA  . THR A 1 574 ? 148.467 144.212 180.281 1.00 143.13 ? 594 THR A CA  1 
ATOM   4318  C C   . THR A 1 574 ? 149.533 145.015 181.024 1.00 149.23 ? 594 THR A C   1 
ATOM   4319  O O   . THR A 1 574 ? 150.089 144.537 182.011 1.00 150.01 ? 594 THR A O   1 
ATOM   4320  C CB  . THR A 1 574 ? 149.057 143.617 178.996 1.00 141.80 ? 594 THR A CB  1 
ATOM   4321  O OG1 . THR A 1 574 ? 149.369 144.678 178.095 1.00 142.00 ? 594 THR A OG1 1 
ATOM   4322  C CG2 . THR A 1 574 ? 148.127 142.638 178.318 1.00 140.41 ? 594 THR A CG2 1 
ATOM   4323  N N   . LEU A 1 575 ? 149.821 146.233 180.546 1.00 154.25 ? 595 LEU A N   1 
ATOM   4324  C CA  . LEU A 1 575 ? 150.871 147.038 181.153 1.00 157.39 ? 595 LEU A CA  1 
ATOM   4325  C C   . LEU A 1 575 ? 150.440 147.487 182.550 1.00 155.69 ? 595 LEU A C   1 
ATOM   4326  O O   . LEU A 1 575 ? 151.267 147.524 183.452 1.00 155.82 ? 595 LEU A O   1 
ATOM   4327  C CB  . LEU A 1 575 ? 151.270 148.210 180.241 1.00 162.09 ? 595 LEU A CB  1 
ATOM   4328  C CG  . LEU A 1 575 ? 150.213 149.272 179.926 1.00 167.00 ? 595 LEU A CG  1 
ATOM   4329  C CD1 . LEU A 1 575 ? 150.251 150.423 180.924 1.00 170.07 ? 595 LEU A CD1 1 
ATOM   4330  C CD2 . LEU A 1 575 ? 150.399 149.808 178.514 1.00 168.22 ? 595 LEU A CD2 1 
ATOM   4331  N N   . PHE A 1 576 ? 149.149 147.788 182.737 1.00 152.34 ? 596 PHE A N   1 
ATOM   4332  C CA  . PHE A 1 576 ? 148.618 148.131 184.051 1.00 150.90 ? 596 PHE A CA  1 
ATOM   4333  C C   . PHE A 1 576 ? 148.834 146.970 185.024 1.00 148.49 ? 596 PHE A C   1 
ATOM   4334  O O   . PHE A 1 576 ? 149.286 147.182 186.148 1.00 148.46 ? 596 PHE A O   1 
ATOM   4335  C CB  . PHE A 1 576 ? 147.141 148.536 183.944 1.00 152.92 ? 596 PHE A CB  1 
ATOM   4336  C CG  . PHE A 1 576 ? 146.327 148.437 185.213 1.00 156.86 ? 596 PHE A CG  1 
ATOM   4337  C CD1 . PHE A 1 576 ? 146.802 148.956 186.409 1.00 158.92 ? 596 PHE A CD1 1 
ATOM   4338  C CD2 . PHE A 1 576 ? 145.083 147.822 185.213 1.00 159.32 ? 596 PHE A CD2 1 
ATOM   4339  C CE1 . PHE A 1 576 ? 146.059 148.852 187.575 1.00 160.50 ? 596 PHE A CE1 1 
ATOM   4340  C CE2 . PHE A 1 576 ? 144.338 147.723 186.379 1.00 161.18 ? 596 PHE A CE2 1 
ATOM   4341  C CZ  . PHE A 1 576 ? 144.824 148.242 187.557 1.00 161.79 ? 596 PHE A CZ  1 
ATOM   4342  N N   . VAL A 1 577 ? 148.500 145.752 184.582 1.00 146.41 ? 597 VAL A N   1 
ATOM   4343  C CA  . VAL A 1 577 ? 148.608 144.559 185.409 1.00 144.52 ? 597 VAL A CA  1 
ATOM   4344  C C   . VAL A 1 577 ? 150.071 144.327 185.788 1.00 143.85 ? 597 VAL A C   1 
ATOM   4345  O O   . VAL A 1 577 ? 150.360 144.010 186.941 1.00 144.30 ? 597 VAL A O   1 
ATOM   4346  C CB  . VAL A 1 577 ? 147.991 143.327 184.712 1.00 144.48 ? 597 VAL A CB  1 
ATOM   4347  C CG1 . VAL A 1 577 ? 148.524 142.008 185.261 1.00 143.35 ? 597 VAL A CG1 1 
ATOM   4348  C CG2 . VAL A 1 577 ? 146.472 143.354 184.777 1.00 144.83 ? 597 VAL A CG2 1 
ATOM   4349  N N   . THR A 1 578 ? 150.985 144.489 184.821 1.00 145.60 ? 598 THR A N   1 
ATOM   4350  C CA  . THR A 1 578 ? 152.395 144.223 185.063 1.00 149.08 ? 598 THR A CA  1 
ATOM   4351  C C   . THR A 1 578 ? 152.946 145.255 186.051 1.00 151.49 ? 598 THR A C   1 
ATOM   4352  O O   . THR A 1 578 ? 153.770 144.921 186.899 1.00 153.16 ? 598 THR A O   1 
ATOM   4353  C CB  . THR A 1 578 ? 153.222 144.193 183.766 1.00 149.86 ? 598 THR A CB  1 
ATOM   4354  O OG1 . THR A 1 578 ? 153.200 145.503 183.198 1.00 149.97 ? 598 THR A OG1 1 
ATOM   4355  C CG2 . THR A 1 578 ? 152.749 143.183 182.741 1.00 149.70 ? 598 THR A CG2 1 
ATOM   4356  N N   . VAL A 1 579 ? 152.476 146.505 185.945 1.00 152.73 ? 599 VAL A N   1 
ATOM   4357  C CA  . VAL A 1 579 ? 152.851 147.545 186.890 1.00 155.81 ? 599 VAL A CA  1 
ATOM   4358  C C   . VAL A 1 579 ? 152.435 147.106 188.290 1.00 153.98 ? 599 VAL A C   1 
ATOM   4359  O O   . VAL A 1 579 ? 153.271 147.056 189.183 1.00 152.17 ? 599 VAL A O   1 
ATOM   4360  C CB  . VAL A 1 579 ? 152.243 148.913 186.516 1.00 160.90 ? 599 VAL A CB  1 
ATOM   4361  C CG1 . VAL A 1 579 ? 152.215 149.884 187.690 1.00 161.70 ? 599 VAL A CG1 1 
ATOM   4362  C CG2 . VAL A 1 579 ? 152.970 149.537 185.333 1.00 163.22 ? 599 VAL A CG2 1 
ATOM   4363  N N   . VAL A 1 580 ? 151.150 146.774 188.468 1.00 155.13 ? 600 VAL A N   1 
ATOM   4364  C CA  . VAL A 1 580 ? 150.641 146.378 189.773 1.00 157.88 ? 600 VAL A CA  1 
ATOM   4365  C C   . VAL A 1 580 ? 151.478 145.221 190.322 1.00 161.71 ? 600 VAL A C   1 
ATOM   4366  O O   . VAL A 1 580 ? 151.804 145.202 191.504 1.00 163.43 ? 600 VAL A O   1 
ATOM   4367  C CB  . VAL A 1 580 ? 149.133 146.053 189.720 1.00 157.03 ? 600 VAL A CB  1 
ATOM   4368  C CG1 . VAL A 1 580 ? 148.681 145.143 190.857 1.00 157.25 ? 600 VAL A CG1 1 
ATOM   4369  C CG2 . VAL A 1 580 ? 148.301 147.327 189.711 1.00 154.90 ? 600 VAL A CG2 1 
ATOM   4370  N N   . PHE A 1 581 ? 151.816 144.254 189.465 1.00 166.91 ? 601 PHE A N   1 
ATOM   4371  C CA  . PHE A 1 581 ? 152.551 143.074 189.892 1.00 172.85 ? 601 PHE A CA  1 
ATOM   4372  C C   . PHE A 1 581 ? 153.932 143.457 190.436 1.00 174.01 ? 601 PHE A C   1 
ATOM   4373  O O   . PHE A 1 581 ? 154.368 142.930 191.461 1.00 174.45 ? 601 PHE A O   1 
ATOM   4374  C CB  . PHE A 1 581 ? 152.696 142.084 188.735 1.00 177.27 ? 601 PHE A CB  1 
ATOM   4375  C CG  . PHE A 1 581 ? 153.384 140.805 189.131 1.00 182.28 ? 601 PHE A CG  1 
ATOM   4376  C CD1 . PHE A 1 581 ? 152.667 139.778 189.721 1.00 184.86 ? 601 PHE A CD1 1 
ATOM   4377  C CD2 . PHE A 1 581 ? 154.758 140.664 188.993 1.00 185.65 ? 601 PHE A CD2 1 
ATOM   4378  C CE1 . PHE A 1 581 ? 153.300 138.608 190.111 1.00 188.79 ? 601 PHE A CE1 1 
ATOM   4379  C CE2 . PHE A 1 581 ? 155.390 139.495 189.387 1.00 189.58 ? 601 PHE A CE2 1 
ATOM   4380  C CZ  . PHE A 1 581 ? 154.660 138.472 189.947 1.00 191.26 ? 601 PHE A CZ  1 
ATOM   4381  N N   . ILE A 1 582 ? 154.614 144.373 189.741 1.00 174.70 ? 602 ILE A N   1 
ATOM   4382  C CA  . ILE A 1 582 ? 156.011 144.667 190.018 1.00 175.68 ? 602 ILE A CA  1 
ATOM   4383  C C   . ILE A 1 582 ? 156.146 145.643 191.185 1.00 174.87 ? 602 ILE A C   1 
ATOM   4384  O O   . ILE A 1 582 ? 157.233 145.745 191.747 1.00 175.32 ? 602 ILE A O   1 
ATOM   4385  C CB  . ILE A 1 582 ? 156.742 145.195 188.766 1.00 176.59 ? 602 ILE A CB  1 
ATOM   4386  C CG1 . ILE A 1 582 ? 156.187 146.541 188.287 1.00 176.42 ? 602 ILE A CG1 1 
ATOM   4387  C CG2 . ILE A 1 582 ? 156.745 144.131 187.676 1.00 176.37 ? 602 ILE A CG2 1 
ATOM   4388  C CD1 . ILE A 1 582 ? 156.895 147.129 187.088 1.00 176.95 ? 602 ILE A CD1 1 
ATOM   4389  N N   . ILE A 1 583 ? 155.086 146.397 191.522 1.00 173.86 ? 603 ILE A N   1 
ATOM   4390  C CA  . ILE A 1 583 ? 155.185 147.356 192.617 1.00 174.08 ? 603 ILE A CA  1 
ATOM   4391  C C   . ILE A 1 583 ? 154.670 146.744 193.924 1.00 174.45 ? 603 ILE A C   1 
ATOM   4392  O O   . ILE A 1 583 ? 154.973 147.269 194.991 1.00 174.59 ? 603 ILE A O   1 
ATOM   4393  C CB  . ILE A 1 583 ? 154.496 148.701 192.289 1.00 174.00 ? 603 ILE A CB  1 
ATOM   4394  C CG1 . ILE A 1 583 ? 152.995 148.671 192.577 1.00 172.32 ? 603 ILE A CG1 1 
ATOM   4395  C CG2 . ILE A 1 583 ? 154.796 149.137 190.862 1.00 174.90 ? 603 ILE A CG2 1 
ATOM   4396  C CD1 . ILE A 1 583 ? 152.287 149.988 192.394 1.00 172.44 ? 603 ILE A CD1 1 
ATOM   4397  N N   . TYR A 1 584 ? 153.872 145.668 193.850 1.00 176.07 ? 604 TYR A N   1 
ATOM   4398  C CA  . TYR A 1 584 ? 153.592 144.827 195.004 1.00 177.98 ? 604 TYR A CA  1 
ATOM   4399  C C   . TYR A 1 584 ? 154.204 143.446 194.765 1.00 180.16 ? 604 TYR A C   1 
ATOM   4400  O O   . TYR A 1 584 ? 153.551 142.576 194.192 1.00 181.20 ? 604 TYR A O   1 
ATOM   4401  C CB  . TYR A 1 584 ? 152.086 144.692 195.248 1.00 179.05 ? 604 TYR A CB  1 
ATOM   4402  C CG  . TYR A 1 584 ? 151.350 145.935 195.681 1.00 182.36 ? 604 TYR A CG  1 
ATOM   4403  C CD1 . TYR A 1 584 ? 151.279 147.050 194.866 1.00 182.97 ? 604 TYR A CD1 1 
ATOM   4404  C CD2 . TYR A 1 584 ? 150.677 145.981 196.892 1.00 184.55 ? 604 TYR A CD2 1 
ATOM   4405  C CE1 . TYR A 1 584 ? 150.586 148.190 195.246 1.00 183.27 ? 604 TYR A CE1 1 
ATOM   4406  C CE2 . TYR A 1 584 ? 149.978 147.111 197.291 1.00 185.72 ? 604 TYR A CE2 1 
ATOM   4407  C CZ  . TYR A 1 584 ? 149.935 148.222 196.467 1.00 185.26 ? 604 TYR A CZ  1 
ATOM   4408  O OH  . TYR A 1 584 ? 149.244 149.344 196.857 1.00 183.97 ? 604 TYR A OH  1 
ATOM   4409  N N   . ARG A 1 585 ? 155.458 143.256 195.199 1.00 184.36 ? 605 ARG A N   1 
ATOM   4410  C CA  . ARG A 1 585 ? 156.186 142.021 194.938 1.00 189.24 ? 605 ARG A CA  1 
ATOM   4411  C C   . ARG A 1 585 ? 156.099 141.085 196.143 1.00 196.67 ? 605 ARG A C   1 
ATOM   4412  O O   . ARG A 1 585 ? 155.765 139.909 195.998 1.00 198.75 ? 605 ARG A O   1 
ATOM   4413  C CB  . ARG A 1 585 ? 157.657 142.306 194.617 1.00 188.64 ? 605 ARG A CB  1 
ATOM   4414  C CG  . ARG A 1 585 ? 157.878 143.259 193.453 1.00 187.81 ? 605 ARG A CG  1 
ATOM   4415  C CD  . ARG A 1 585 ? 159.357 143.485 193.200 1.00 187.95 ? 605 ARG A CD  1 
ATOM   4416  N NE  . ARG A 1 585 ? 159.604 144.484 192.168 1.00 188.92 ? 605 ARG A NE  1 
ATOM   4417  C CZ  . ARG A 1 585 ? 160.807 144.902 191.779 1.00 188.94 ? 605 ARG A CZ  1 
ATOM   4418  N NH1 . ARG A 1 585 ? 161.902 144.402 192.326 1.00 187.52 ? 605 ARG A NH1 1 
ATOM   4419  N NH2 . ARG A 1 585 ? 160.909 145.825 190.836 1.00 188.68 ? 605 ARG A NH2 1 
ATOM   4420  N N   . ASP A 1 586 ? 156.432 141.606 197.332 1.00 202.30 ? 606 ASP A N   1 
ATOM   4421  C CA  . ASP A 1 586 ? 156.571 140.786 198.528 1.00 206.53 ? 606 ASP A CA  1 
ATOM   4422  C C   . ASP A 1 586 ? 155.270 140.755 199.335 1.00 206.34 ? 606 ASP A C   1 
ATOM   4423  O O   . ASP A 1 586 ? 155.274 140.309 200.478 1.00 204.39 ? 606 ASP A O   1 
ATOM   4424  C CB  . ASP A 1 586 ? 157.740 141.283 199.381 1.00 209.79 ? 606 ASP A CB  1 
ATOM   4425  C CG  . ASP A 1 586 ? 159.090 141.187 198.689 1.00 213.29 ? 606 ASP A CG  1 
ATOM   4426  O OD1 . ASP A 1 586 ? 159.487 140.058 198.336 1.00 213.37 ? 606 ASP A OD1 1 
ATOM   4427  O OD2 . ASP A 1 586 ? 159.732 142.241 198.508 1.00 214.17 ? 606 ASP A OD2 1 
ATOM   4428  N N   . THR A 1 587 ? 154.174 141.232 198.731 1.00 208.24 ? 607 THR A N   1 
ATOM   4429  C CA  . THR A 1 587 ? 152.851 141.137 199.324 1.00 209.99 ? 607 THR A CA  1 
ATOM   4430  C C   . THR A 1 587 ? 152.418 139.674 199.367 1.00 210.15 ? 607 THR A C   1 
ATOM   4431  O O   . THR A 1 587 ? 152.588 138.951 198.389 1.00 207.44 ? 607 THR A O   1 
ATOM   4432  C CB  . THR A 1 587 ? 151.855 141.994 198.536 1.00 211.94 ? 607 THR A CB  1 
ATOM   4433  O OG1 . THR A 1 587 ? 152.248 143.356 198.712 1.00 212.04 ? 607 THR A OG1 1 
ATOM   4434  C CG2 . THR A 1 587 ? 150.422 141.809 198.984 1.00 211.66 ? 607 THR A CG2 1 
ATOM   4435  N N   . PRO A 1 588 ? 151.807 139.196 200.478 1.00 212.17 ? 608 PRO A N   1 
ATOM   4436  C CA  . PRO A 1 588 ? 151.335 137.811 200.554 1.00 212.83 ? 608 PRO A CA  1 
ATOM   4437  C C   . PRO A 1 588 ? 150.354 137.408 199.452 1.00 212.82 ? 608 PRO A C   1 
ATOM   4438  O O   . PRO A 1 588 ? 150.152 136.218 199.229 1.00 211.43 ? 608 PRO A O   1 
ATOM   4439  C CB  . PRO A 1 588 ? 150.661 137.713 201.937 1.00 212.52 ? 608 PRO A CB  1 
ATOM   4440  C CG  . PRO A 1 588 ? 150.441 139.146 202.385 1.00 212.36 ? 608 PRO A CG  1 
ATOM   4441  C CD  . PRO A 1 588 ? 151.545 139.941 201.721 1.00 212.23 ? 608 PRO A CD  1 
ATOM   4442  N N   . VAL A 1 589 ? 149.726 138.391 198.788 1.00 212.04 ? 609 VAL A N   1 
ATOM   4443  C CA  . VAL A 1 589 ? 148.809 138.124 197.687 1.00 210.93 ? 609 VAL A CA  1 
ATOM   4444  C C   . VAL A 1 589 ? 149.532 137.315 196.610 1.00 213.00 ? 609 VAL A C   1 
ATOM   4445  O O   . VAL A 1 589 ? 149.032 136.277 196.173 1.00 212.42 ? 609 VAL A O   1 
ATOM   4446  C CB  . VAL A 1 589 ? 148.207 139.424 197.115 1.00 206.92 ? 609 VAL A CB  1 
ATOM   4447  C CG1 . VAL A 1 589 ? 147.430 139.183 195.828 1.00 205.80 ? 609 VAL A CG1 1 
ATOM   4448  C CG2 . VAL A 1 589 ? 147.333 140.135 198.139 1.00 205.31 ? 609 VAL A CG2 1 
ATOM   4449  N N   . VAL A 1 590 ? 150.692 137.819 196.171 1.00 215.26 ? 610 VAL A N   1 
ATOM   4450  C CA  . VAL A 1 590 ? 151.561 137.073 195.272 1.00 218.22 ? 610 VAL A CA  1 
ATOM   4451  C C   . VAL A 1 590 ? 152.721 136.533 196.104 1.00 223.12 ? 610 VAL A C   1 
ATOM   4452  O O   . VAL A 1 590 ? 153.769 137.166 196.209 1.00 220.04 ? 610 VAL A O   1 
ATOM   4453  C CB  . VAL A 1 590 ? 152.036 137.890 194.046 1.00 216.21 ? 610 VAL A CB  1 
ATOM   4454  C CG1 . VAL A 1 590 ? 152.593 139.257 194.414 1.00 214.46 ? 610 VAL A CG1 1 
ATOM   4455  C CG2 . VAL A 1 590 ? 153.040 137.119 193.199 1.00 216.04 ? 610 VAL A CG2 1 
ATOM   4456  N N   . LYS A 1 591 ? 152.518 135.355 196.704 1.00 231.80 ? 611 LYS A N   1 
ATOM   4457  C CA  . LYS A 1 591 ? 153.555 134.708 197.494 1.00 240.55 ? 611 LYS A CA  1 
ATOM   4458  C C   . LYS A 1 591 ? 153.784 133.284 196.995 1.00 243.15 ? 611 LYS A C   1 
ATOM   4459  O O   . LYS A 1 591 ? 154.919 132.919 196.710 1.00 242.33 ? 611 LYS A O   1 
ATOM   4460  C CB  . LYS A 1 591 ? 153.184 134.723 198.980 1.00 246.17 ? 611 LYS A CB  1 
ATOM   4461  C CG  . LYS A 1 591 ? 154.254 134.181 199.917 1.00 250.69 ? 611 LYS A CG  1 
ATOM   4462  C CD  . LYS A 1 591 ? 153.898 134.324 201.383 1.00 253.32 ? 611 LYS A CD  1 
ATOM   4463  C CE  . LYS A 1 591 ? 154.966 133.784 202.310 1.00 253.61 ? 611 LYS A CE  1 
ATOM   4464  N NZ  . LYS A 1 591 ? 154.585 133.942 203.734 1.00 252.47 ? 611 LYS A NZ  1 
ATOM   4465  N N   . SER A 1 592 ? 152.706 132.492 196.933 1.00 246.86 ? 612 SER A N   1 
ATOM   4466  C CA  . SER A 1 592 ? 152.759 131.099 196.520 1.00 249.85 ? 612 SER A CA  1 
ATOM   4467  C C   . SER A 1 592 ? 152.999 130.985 195.014 1.00 248.35 ? 612 SER A C   1 
ATOM   4468  O O   . SER A 1 592 ? 153.849 130.209 194.575 1.00 246.20 ? 612 SER A O   1 
ATOM   4469  C CB  . SER A 1 592 ? 151.490 130.387 196.924 1.00 251.24 ? 612 SER A CB  1 
ATOM   4470  O OG  . SER A 1 592 ? 150.342 131.052 196.413 1.00 251.61 ? 612 SER A OG  1 
ATOM   4471  N N   . SER A 1 593 ? 152.249 131.783 194.242 1.00 243.95 ? 613 SER A N   1 
ATOM   4472  C CA  . SER A 1 593 ? 152.409 131.851 192.798 1.00 238.88 ? 613 SER A CA  1 
ATOM   4473  C C   . SER A 1 593 ? 153.859 132.169 192.439 1.00 231.51 ? 613 SER A C   1 
ATOM   4474  O O   . SER A 1 593 ? 154.376 133.225 192.804 1.00 229.54 ? 613 SER A O   1 
ATOM   4475  C CB  . SER A 1 593 ? 151.470 132.866 192.197 1.00 238.85 ? 613 SER A CB  1 
ATOM   4476  O OG  . SER A 1 593 ? 151.682 134.155 192.750 1.00 238.78 ? 613 SER A OG  1 
ATOM   4477  N N   . SER A 1 594 ? 154.503 131.241 191.718 1.00 223.01 ? 614 SER A N   1 
ATOM   4478  C CA  . SER A 1 594 ? 155.857 131.443 191.232 1.00 216.33 ? 614 SER A CA  1 
ATOM   4479  C C   . SER A 1 594 ? 155.913 132.723 190.402 1.00 211.11 ? 614 SER A C   1 
ATOM   4480  O O   . SER A 1 594 ? 155.279 132.817 189.351 1.00 208.09 ? 614 SER A O   1 
ATOM   4481  C CB  . SER A 1 594 ? 156.335 130.254 190.436 1.00 214.56 ? 614 SER A CB  1 
ATOM   4482  O OG  . SER A 1 594 ? 157.683 130.428 190.017 1.00 213.82 ? 614 SER A OG  1 
ATOM   4483  N N   . ARG A 1 595 ? 156.688 133.700 190.889 1.00 207.24 ? 615 ARG A N   1 
ATOM   4484  C CA  . ARG A 1 595 ? 156.800 135.002 190.250 1.00 203.99 ? 615 ARG A CA  1 
ATOM   4485  C C   . ARG A 1 595 ? 157.259 134.838 188.801 1.00 195.44 ? 615 ARG A C   1 
ATOM   4486  O O   . ARG A 1 595 ? 156.843 135.594 187.924 1.00 190.49 ? 615 ARG A O   1 
ATOM   4487  C CB  . ARG A 1 595 ? 157.786 135.890 191.013 1.00 208.63 ? 615 ARG A CB  1 
ATOM   4488  C CG  . ARG A 1 595 ? 157.403 136.157 192.461 1.00 211.66 ? 615 ARG A CG  1 
ATOM   4489  C CD  . ARG A 1 595 ? 158.544 136.802 193.223 1.00 213.71 ? 615 ARG A CD  1 
ATOM   4490  N NE  . ARG A 1 595 ? 159.718 135.937 193.293 1.00 217.76 ? 615 ARG A NE  1 
ATOM   4491  C CZ  . ARG A 1 595 ? 160.907 136.292 193.775 1.00 220.78 ? 615 ARG A CZ  1 
ATOM   4492  N NH1 . ARG A 1 595 ? 161.098 137.502 194.274 1.00 220.59 ? 615 ARG A NH1 1 
ATOM   4493  N NH2 . ARG A 1 595 ? 161.909 135.428 193.758 1.00 220.77 ? 615 ARG A NH2 1 
ATOM   4494  N N   . GLU A 1 596 ? 158.094 133.820 188.560 1.00 191.24 ? 616 GLU A N   1 
ATOM   4495  C CA  . GLU A 1 596 ? 158.632 133.557 187.235 1.00 188.53 ? 616 GLU A CA  1 
ATOM   4496  C C   . GLU A 1 596 ? 157.503 133.108 186.307 1.00 179.85 ? 616 GLU A C   1 
ATOM   4497  O O   . GLU A 1 596 ? 157.419 133.578 185.174 1.00 177.76 ? 616 GLU A O   1 
ATOM   4498  C CB  . GLU A 1 596 ? 159.743 132.504 187.274 1.00 192.09 ? 616 GLU A CB  1 
ATOM   4499  C CG  . GLU A 1 596 ? 160.938 132.890 188.134 1.00 195.51 ? 616 GLU A CG  1 
ATOM   4500  C CD  . GLU A 1 596 ? 160.745 132.768 189.638 1.00 197.62 ? 616 GLU A CD  1 
ATOM   4501  O OE1 . GLU A 1 596 ? 159.657 132.328 190.063 1.00 197.28 ? 616 GLU A OE1 1 
ATOM   4502  O OE2 . GLU A 1 596 ? 161.684 133.116 190.384 1.00 197.47 ? 616 GLU A OE2 1 
ATOM   4503  N N   . LEU A 1 597 ? 156.632 132.217 186.804 1.00 170.03 ? 617 LEU A N   1 
ATOM   4504  C CA  . LEU A 1 597 ? 155.510 131.733 186.014 1.00 163.32 ? 617 LEU A CA  1 
ATOM   4505  C C   . LEU A 1 597 ? 154.596 132.900 185.651 1.00 161.41 ? 617 LEU A C   1 
ATOM   4506  O O   . LEU A 1 597 ? 154.132 132.989 184.514 1.00 160.34 ? 617 LEU A O   1 
ATOM   4507  C CB  . LEU A 1 597 ? 154.730 130.668 186.792 1.00 161.17 ? 617 LEU A CB  1 
ATOM   4508  C CG  . LEU A 1 597 ? 155.416 129.316 186.987 1.00 160.69 ? 617 LEU A CG  1 
ATOM   4509  C CD1 . LEU A 1 597 ? 154.394 128.272 187.413 1.00 159.45 ? 617 LEU A CD1 1 
ATOM   4510  C CD2 . LEU A 1 597 ? 156.145 128.860 185.729 1.00 159.75 ? 617 LEU A CD2 1 
ATOM   4511  N N   . CYS A 1 598 ? 154.351 133.796 186.615 1.00 162.12 ? 618 CYS A N   1 
ATOM   4512  C CA  . CYS A 1 598 ? 153.507 134.953 186.364 1.00 165.40 ? 618 CYS A CA  1 
ATOM   4513  C C   . CYS A 1 598 ? 154.135 135.808 185.266 1.00 163.58 ? 618 CYS A C   1 
ATOM   4514  O O   . CYS A 1 598 ? 153.444 136.194 184.324 1.00 163.71 ? 618 CYS A O   1 
ATOM   4515  C CB  . CYS A 1 598 ? 153.277 135.764 187.632 1.00 169.99 ? 618 CYS A CB  1 
ATOM   4516  S SG  . CYS A 1 598 ? 152.167 134.955 188.814 1.00 174.12 ? 618 CYS A SG  1 
ATOM   4517  N N   . TYR A 1 599 ? 155.453 136.030 185.364 1.00 160.24 ? 619 TYR A N   1 
ATOM   4518  C CA  . TYR A 1 599 ? 156.179 136.790 184.357 1.00 158.22 ? 619 TYR A CA  1 
ATOM   4519  C C   . TYR A 1 599 ? 155.978 136.174 182.973 1.00 146.16 ? 619 TYR A C   1 
ATOM   4520  O O   . TYR A 1 599 ? 155.792 136.906 182.000 1.00 143.45 ? 619 TYR A O   1 
ATOM   4521  C CB  . TYR A 1 599 ? 157.665 136.893 184.706 1.00 166.43 ? 619 TYR A CB  1 
ATOM   4522  C CG  . TYR A 1 599 ? 158.090 138.191 185.343 1.00 175.49 ? 619 TYR A CG  1 
ATOM   4523  C CD1 . TYR A 1 599 ? 157.475 138.684 186.485 1.00 178.61 ? 619 TYR A CD1 1 
ATOM   4524  C CD2 . TYR A 1 599 ? 159.126 138.932 184.797 1.00 180.68 ? 619 TYR A CD2 1 
ATOM   4525  C CE1 . TYR A 1 599 ? 157.874 139.880 187.061 1.00 182.46 ? 619 TYR A CE1 1 
ATOM   4526  C CE2 . TYR A 1 599 ? 159.541 140.127 185.362 1.00 183.07 ? 619 TYR A CE2 1 
ATOM   4527  C CZ  . TYR A 1 599 ? 158.912 140.604 186.499 1.00 184.34 ? 619 TYR A CZ  1 
ATOM   4528  O OH  . TYR A 1 599 ? 159.321 141.789 187.062 1.00 182.89 ? 619 TYR A OH  1 
ATOM   4529  N N   . ILE A 1 600 ? 156.038 134.839 182.895 1.00 134.89 ? 620 ILE A N   1 
ATOM   4530  C CA  . ILE A 1 600 ? 155.886 134.151 181.623 1.00 128.31 ? 620 ILE A CA  1 
ATOM   4531  C C   . ILE A 1 600 ? 154.484 134.422 181.079 1.00 124.38 ? 620 ILE A C   1 
ATOM   4532  O O   . ILE A 1 600 ? 154.331 134.686 179.887 1.00 125.45 ? 620 ILE A O   1 
ATOM   4533  C CB  . ILE A 1 600 ? 156.189 132.641 181.748 1.00 126.06 ? 620 ILE A CB  1 
ATOM   4534  C CG1 . ILE A 1 600 ? 157.562 132.364 182.370 1.00 125.78 ? 620 ILE A CG1 1 
ATOM   4535  C CG2 . ILE A 1 600 ? 156.056 131.945 180.405 1.00 124.93 ? 620 ILE A CG2 1 
ATOM   4536  C CD1 . ILE A 1 600 ? 158.718 133.065 181.689 1.00 125.66 ? 620 ILE A CD1 1 
ATOM   4537  N N   . ILE A 1 601 ? 153.470 134.376 181.954 1.00 120.01 ? 621 ILE A N   1 
ATOM   4538  C CA  . ILE A 1 601 ? 152.089 134.595 181.541 1.00 117.74 ? 621 ILE A CA  1 
ATOM   4539  C C   . ILE A 1 601 ? 151.933 136.011 180.984 1.00 116.66 ? 621 ILE A C   1 
ATOM   4540  O O   . ILE A 1 601 ? 151.304 136.192 179.942 1.00 117.75 ? 621 ILE A O   1 
ATOM   4541  C CB  . ILE A 1 601 ? 151.091 134.317 182.691 1.00 118.17 ? 621 ILE A CB  1 
ATOM   4542  C CG1 . ILE A 1 601 ? 150.615 132.861 182.722 1.00 118.16 ? 621 ILE A CG1 1 
ATOM   4543  C CG2 . ILE A 1 601 ? 149.885 135.245 182.624 1.00 117.14 ? 621 ILE A CG2 1 
ATOM   4544  C CD1 . ILE A 1 601 ? 151.714 131.839 182.786 1.00 117.56 ? 621 ILE A CD1 1 
ATOM   4545  N N   . LEU A 1 602 ? 152.489 137.004 181.690 1.00 117.84 ? 622 LEU A N   1 
ATOM   4546  C CA  . LEU A 1 602 ? 152.333 138.392 181.279 1.00 121.15 ? 622 LEU A CA  1 
ATOM   4547  C C   . LEU A 1 602 ? 153.000 138.595 179.922 1.00 117.03 ? 622 LEU A C   1 
ATOM   4548  O O   . LEU A 1 602 ? 152.421 139.245 179.053 1.00 115.26 ? 622 LEU A O   1 
ATOM   4549  C CB  . LEU A 1 602 ? 152.908 139.351 182.331 1.00 126.99 ? 622 LEU A CB  1 
ATOM   4550  C CG  . LEU A 1 602 ? 152.134 139.453 183.650 1.00 131.88 ? 622 LEU A CG  1 
ATOM   4551  C CD1 . LEU A 1 602 ? 152.839 140.380 184.637 1.00 134.12 ? 622 LEU A CD1 1 
ATOM   4552  C CD2 . LEU A 1 602 ? 150.696 139.916 183.434 1.00 133.23 ? 622 LEU A CD2 1 
ATOM   4553  N N   . ALA A 1 603 ? 154.201 138.024 179.741 1.00 113.26 ? 623 ALA A N   1 
ATOM   4554  C CA  . ALA A 1 603 ? 154.921 138.144 178.482 1.00 111.85 ? 623 ALA A CA  1 
ATOM   4555  C C   . ALA A 1 603 ? 154.108 137.520 177.349 1.00 109.13 ? 623 ALA A C   1 
ATOM   4556  O O   . ALA A 1 603 ? 154.035 138.073 176.252 1.00 107.30 ? 623 ALA A O   1 
ATOM   4557  C CB  . ALA A 1 603 ? 156.283 137.501 178.593 1.00 113.03 ? 623 ALA A CB  1 
ATOM   4558  N N   . GLY A 1 604 ? 153.507 136.359 177.635 1.00 109.05 ? 624 GLY A N   1 
ATOM   4559  C CA  . GLY A 1 604 ? 152.660 135.677 176.673 1.00 108.59 ? 624 GLY A CA  1 
ATOM   4560  C C   . GLY A 1 604 ? 151.491 136.551 176.227 1.00 105.74 ? 624 GLY A C   1 
ATOM   4561  O O   . GLY A 1 604 ? 151.216 136.661 175.033 1.00 105.21 ? 624 GLY A O   1 
ATOM   4562  N N   . ILE A 1 605 ? 150.823 137.180 177.200 1.00 103.82 ? 625 ILE A N   1 
ATOM   4563  C CA  . ILE A 1 605 ? 149.652 137.989 176.910 1.00 105.26 ? 625 ILE A CA  1 
ATOM   4564  C C   . ILE A 1 605 ? 150.074 139.198 176.076 1.00 106.41 ? 625 ILE A C   1 
ATOM   4565  O O   . ILE A 1 605 ? 149.382 139.567 175.127 1.00 105.76 ? 625 ILE A O   1 
ATOM   4566  C CB  . ILE A 1 605 ? 148.913 138.384 178.204 1.00 106.96 ? 625 ILE A CB  1 
ATOM   4567  C CG1 . ILE A 1 605 ? 148.431 137.143 178.965 1.00 109.58 ? 625 ILE A CG1 1 
ATOM   4568  C CG2 . ILE A 1 605 ? 147.763 139.327 177.892 1.00 106.91 ? 625 ILE A CG2 1 
ATOM   4569  C CD1 . ILE A 1 605 ? 147.550 137.433 180.164 1.00 110.69 ? 625 ILE A CD1 1 
ATOM   4570  N N   . CYS A 1 606 ? 151.213 139.805 176.428 1.00 108.69 ? 626 CYS A N   1 
ATOM   4571  C CA  . CYS A 1 606 ? 151.705 140.968 175.706 1.00 111.32 ? 626 CYS A CA  1 
ATOM   4572  C C   . CYS A 1 606 ? 151.957 140.610 174.243 1.00 107.02 ? 626 CYS A C   1 
ATOM   4573  O O   . CYS A 1 606 ? 151.481 141.308 173.353 1.00 105.17 ? 626 CYS A O   1 
ATOM   4574  C CB  . CYS A 1 606 ? 152.973 141.533 176.337 1.00 116.16 ? 626 CYS A CB  1 
ATOM   4575  S SG  . CYS A 1 606 ? 153.419 143.168 175.694 1.00 124.15 ? 626 CYS A SG  1 
ATOM   4576  N N   . LEU A 1 607 ? 152.693 139.519 173.996 1.00 103.42 ? 627 LEU A N   1 
ATOM   4577  C CA  . LEU A 1 607 ? 153.058 139.151 172.638 1.00 100.63 ? 627 LEU A CA  1 
ATOM   4578  C C   . LEU A 1 607 ? 151.826 138.709 171.852 1.00 96.46  ? 627 LEU A C   1 
ATOM   4579  O O   . LEU A 1 607 ? 151.755 138.929 170.644 1.00 96.48  ? 627 LEU A O   1 
ATOM   4580  C CB  . LEU A 1 607 ? 154.113 138.044 172.681 1.00 102.26 ? 627 LEU A CB  1 
ATOM   4581  C CG  . LEU A 1 607 ? 155.326 138.297 171.792 1.00 105.25 ? 627 LEU A CG  1 
ATOM   4582  C CD1 . LEU A 1 607 ? 156.031 139.591 172.177 1.00 106.85 ? 627 LEU A CD1 1 
ATOM   4583  C CD2 . LEU A 1 607 ? 156.297 137.138 171.881 1.00 105.73 ? 627 LEU A CD2 1 
ATOM   4584  N N   . GLY A 1 608 ? 150.862 138.097 172.552 1.00 93.31  ? 628 GLY A N   1 
ATOM   4585  C CA  . GLY A 1 608 ? 149.571 137.770 171.968 1.00 91.02  ? 628 GLY A CA  1 
ATOM   4586  C C   . GLY A 1 608 ? 148.867 139.009 171.410 1.00 90.71  ? 628 GLY A C   1 
ATOM   4587  O O   . GLY A 1 608 ? 148.355 138.998 170.290 1.00 91.35  ? 628 GLY A O   1 
ATOM   4588  N N   . TYR A 1 609 ? 148.851 140.084 172.204 1.00 90.10  ? 629 TYR A N   1 
ATOM   4589  C CA  . TYR A 1 609 ? 148.250 141.330 171.764 1.00 90.70  ? 629 TYR A CA  1 
ATOM   4590  C C   . TYR A 1 609 ? 149.068 141.951 170.636 1.00 89.73  ? 629 TYR A C   1 
ATOM   4591  O O   . TYR A 1 609 ? 148.485 142.508 169.713 1.00 88.49  ? 629 TYR A O   1 
ATOM   4592  C CB  . TYR A 1 609 ? 148.066 142.296 172.937 1.00 93.68  ? 629 TYR A CB  1 
ATOM   4593  C CG  . TYR A 1 609 ? 146.851 141.984 173.771 1.00 95.78  ? 629 TYR A CG  1 
ATOM   4594  C CD1 . TYR A 1 609 ? 145.592 141.964 173.194 1.00 97.02  ? 629 TYR A CD1 1 
ATOM   4595  C CD2 . TYR A 1 609 ? 146.951 141.702 175.123 1.00 96.30  ? 629 TYR A CD2 1 
ATOM   4596  C CE1 . TYR A 1 609 ? 144.460 141.675 173.938 1.00 97.43  ? 629 TYR A CE1 1 
ATOM   4597  C CE2 . TYR A 1 609 ? 145.833 141.399 175.881 1.00 97.10  ? 629 TYR A CE2 1 
ATOM   4598  C CZ  . TYR A 1 609 ? 144.583 141.392 175.287 1.00 97.54  ? 629 TYR A CZ  1 
ATOM   4599  O OH  . TYR A 1 609 ? 143.469 141.098 176.032 1.00 95.79  ? 629 TYR A OH  1 
ATOM   4600  N N   . LEU A 1 610 ? 150.402 141.853 170.709 1.00 91.10  ? 630 LEU A N   1 
ATOM   4601  C CA  . LEU A 1 610 ? 151.263 142.477 169.713 1.00 92.50  ? 630 LEU A CA  1 
ATOM   4602  C C   . LEU A 1 610 ? 151.047 141.842 168.338 1.00 88.53  ? 630 LEU A C   1 
ATOM   4603  O O   . LEU A 1 610 ? 151.034 142.546 167.320 1.00 88.29  ? 630 LEU A O   1 
ATOM   4604  C CB  . LEU A 1 610 ? 152.729 142.379 170.162 1.00 97.74  ? 630 LEU A CB  1 
ATOM   4605  C CG  . LEU A 1 610 ? 153.786 142.398 169.055 1.00 102.89 ? 630 LEU A CG  1 
ATOM   4606  C CD1 . LEU A 1 610 ? 153.799 143.729 168.315 1.00 104.54 ? 630 LEU A CD1 1 
ATOM   4607  C CD2 . LEU A 1 610 ? 155.165 142.095 169.623 1.00 105.19 ? 630 LEU A CD2 1 
ATOM   4608  N N   . CYS A 1 611 ? 150.843 140.518 168.300 1.00 85.54  ? 631 CYS A N   1 
ATOM   4609  C CA  . CYS A 1 611 ? 150.728 139.850 167.012 1.00 83.20  ? 631 CYS A CA  1 
ATOM   4610  C C   . CYS A 1 611 ? 149.416 140.226 166.319 1.00 79.26  ? 631 CYS A C   1 
ATOM   4611  O O   . CYS A 1 611 ? 149.270 139.979 165.127 1.00 79.38  ? 631 CYS A O   1 
ATOM   4612  C CB  . CYS A 1 611 ? 150.915 138.339 167.108 1.00 85.33  ? 631 CYS A CB  1 
ATOM   4613  S SG  . CYS A 1 611 ? 149.990 137.554 168.451 1.00 89.38  ? 631 CYS A SG  1 
ATOM   4614  N N   . THR A 1 612 ? 148.476 140.859 167.032 1.00 78.37  ? 632 THR A N   1 
ATOM   4615  C CA  . THR A 1 612 ? 147.291 141.399 166.381 1.00 79.32  ? 632 THR A CA  1 
ATOM   4616  C C   . THR A 1 612 ? 147.695 142.485 165.386 1.00 80.77  ? 632 THR A C   1 
ATOM   4617  O O   . THR A 1 612 ? 147.264 142.459 164.238 1.00 80.69  ? 632 THR A O   1 
ATOM   4618  C CB  . THR A 1 612 ? 146.263 141.937 167.381 1.00 79.01  ? 632 THR A CB  1 
ATOM   4619  O OG1 . THR A 1 612 ? 145.579 140.826 167.962 1.00 78.56  ? 632 THR A OG1 1 
ATOM   4620  C CG2 . THR A 1 612 ? 145.258 142.867 166.737 1.00 77.76  ? 632 THR A CG2 1 
ATOM   4621  N N   . PHE A 1 613 ? 148.502 143.451 165.838 1.00 83.78  ? 633 PHE A N   1 
ATOM   4622  C CA  . PHE A 1 613 ? 149.030 144.485 164.960 1.00 84.86  ? 633 PHE A CA  1 
ATOM   4623  C C   . PHE A 1 613 ? 149.926 143.856 163.896 1.00 84.17  ? 633 PHE A C   1 
ATOM   4624  O O   . PHE A 1 613 ? 149.899 144.274 162.743 1.00 84.39  ? 633 PHE A O   1 
ATOM   4625  C CB  . PHE A 1 613 ? 149.808 145.539 165.748 1.00 85.83  ? 633 PHE A CB  1 
ATOM   4626  C CG  . PHE A 1 613 ? 149.010 146.192 166.842 1.00 88.16  ? 633 PHE A CG  1 
ATOM   4627  C CD1 . PHE A 1 613 ? 147.861 146.910 166.548 1.00 89.18  ? 633 PHE A CD1 1 
ATOM   4628  C CD2 . PHE A 1 613 ? 149.399 146.072 168.165 1.00 91.53  ? 633 PHE A CD2 1 
ATOM   4629  C CE1 . PHE A 1 613 ? 147.125 147.512 167.558 1.00 91.68  ? 633 PHE A CE1 1 
ATOM   4630  C CE2 . PHE A 1 613 ? 148.665 146.679 169.174 1.00 94.56  ? 633 PHE A CE2 1 
ATOM   4631  C CZ  . PHE A 1 613 ? 147.522 147.387 168.871 1.00 93.79  ? 633 PHE A CZ  1 
ATOM   4632  N N   . CYS A 1 614 ? 150.687 142.824 164.282 1.00 83.53  ? 634 CYS A N   1 
ATOM   4633  C CA  . CYS A 1 614 ? 151.563 142.114 163.364 1.00 83.16  ? 634 CYS A CA  1 
ATOM   4634  C C   . CYS A 1 614 ? 150.774 141.421 162.248 1.00 81.47  ? 634 CYS A C   1 
ATOM   4635  O O   . CYS A 1 614 ? 151.344 141.105 161.210 1.00 82.12  ? 634 CYS A O   1 
ATOM   4636  C CB  . CYS A 1 614 ? 152.397 141.091 164.125 1.00 84.54  ? 634 CYS A CB  1 
ATOM   4637  S SG  . CYS A 1 614 ? 153.456 140.077 163.064 1.00 85.00  ? 634 CYS A SG  1 
ATOM   4638  N N   . LEU A 1 615 ? 149.467 141.197 162.458 1.00 80.26  ? 635 LEU A N   1 
ATOM   4639  C CA  . LEU A 1 615 ? 148.622 140.549 161.466 1.00 78.85  ? 635 LEU A CA  1 
ATOM   4640  C C   . LEU A 1 615 ? 147.973 141.577 160.540 1.00 78.86  ? 635 LEU A C   1 
ATOM   4641  O O   . LEU A 1 615 ? 148.142 141.506 159.324 1.00 78.73  ? 635 LEU A O   1 
ATOM   4642  C CB  . LEU A 1 615 ? 147.542 139.723 162.167 1.00 78.36  ? 635 LEU A CB  1 
ATOM   4643  C CG  . LEU A 1 615 ? 147.686 138.205 162.100 1.00 78.36  ? 635 LEU A CG  1 
ATOM   4644  C CD1 . LEU A 1 615 ? 148.900 137.733 162.876 1.00 79.86  ? 635 LEU A CD1 1 
ATOM   4645  C CD2 . LEU A 1 615 ? 146.427 137.539 162.630 1.00 77.78  ? 635 LEU A CD2 1 
ATOM   4646  N N   . ILE A 1 616 ? 147.220 142.517 161.124 1.00 81.91  ? 636 ILE A N   1 
ATOM   4647  C CA  . ILE A 1 616 ? 146.517 143.526 160.344 1.00 85.41  ? 636 ILE A CA  1 
ATOM   4648  C C   . ILE A 1 616 ? 147.530 144.562 159.860 1.00 89.14  ? 636 ILE A C   1 
ATOM   4649  O O   . ILE A 1 616 ? 147.870 145.489 160.585 1.00 89.84  ? 636 ILE A O   1 
ATOM   4650  C CB  . ILE A 1 616 ? 145.343 144.163 161.124 1.00 86.32  ? 636 ILE A CB  1 
ATOM   4651  C CG1 . ILE A 1 616 ? 144.799 145.409 160.421 1.00 88.04  ? 636 ILE A CG1 1 
ATOM   4652  C CG2 . ILE A 1 616 ? 145.693 144.486 162.571 1.00 86.70  ? 636 ILE A CG2 1 
ATOM   4653  C CD1 . ILE A 1 616 ? 144.360 145.176 159.001 1.00 90.39  ? 636 ILE A CD1 1 
ATOM   4654  N N   . ALA A 1 617 ? 148.006 144.387 158.624 1.00 94.50  ? 637 ALA A N   1 
ATOM   4655  C CA  . ALA A 1 617 ? 149.019 145.258 158.048 1.00 100.07 ? 637 ALA A CA  1 
ATOM   4656  C C   . ALA A 1 617 ? 149.240 144.883 156.584 1.00 104.32 ? 637 ALA A C   1 
ATOM   4657  O O   . ALA A 1 617 ? 148.601 143.964 156.073 1.00 106.07 ? 637 ALA A O   1 
ATOM   4658  C CB  . ALA A 1 617 ? 150.309 145.153 158.830 1.00 100.36 ? 637 ALA A CB  1 
ATOM   4659  N N   . LYS A 1 618 ? 150.125 145.633 155.918 1.00 106.49 ? 638 LYS A N   1 
ATOM   4660  C CA  . LYS A 1 618 ? 150.579 145.278 154.585 1.00 108.06 ? 638 LYS A CA  1 
ATOM   4661  C C   . LYS A 1 618 ? 151.433 144.017 154.677 1.00 106.77 ? 638 LYS A C   1 
ATOM   4662  O O   . LYS A 1 618 ? 152.460 144.021 155.353 1.00 108.77 ? 638 LYS A O   1 
ATOM   4663  C CB  . LYS A 1 618 ? 151.351 146.438 153.949 1.00 111.66 ? 638 LYS A CB  1 
ATOM   4664  C CG  . LYS A 1 618 ? 150.491 147.436 153.184 1.00 114.35 ? 638 LYS A CG  1 
ATOM   4665  C CD  . LYS A 1 618 ? 149.682 146.816 152.057 1.00 115.95 ? 638 LYS A CD  1 
ATOM   4666  C CE  . LYS A 1 618 ? 150.479 145.824 151.234 1.00 116.71 ? 638 LYS A CE  1 
ATOM   4667  N NZ  . LYS A 1 618 ? 149.759 145.413 150.008 1.00 116.54 ? 638 LYS A NZ  1 
ATOM   4668  N N   . PRO A 1 619 ? 151.032 142.901 154.025 1.00 103.74 ? 639 PRO A N   1 
ATOM   4669  C CA  . PRO A 1 619 ? 151.794 141.655 154.108 1.00 102.75 ? 639 PRO A CA  1 
ATOM   4670  C C   . PRO A 1 619 ? 153.200 141.788 153.527 1.00 104.28 ? 639 PRO A C   1 
ATOM   4671  O O   . PRO A 1 619 ? 153.371 141.964 152.321 1.00 104.66 ? 639 PRO A O   1 
ATOM   4672  C CB  . PRO A 1 619 ? 150.955 140.648 153.304 1.00 103.87 ? 639 PRO A CB  1 
ATOM   4673  C CG  . PRO A 1 619 ? 149.571 141.263 153.255 1.00 104.82 ? 639 PRO A CG  1 
ATOM   4674  C CD  . PRO A 1 619 ? 149.816 142.757 153.206 1.00 104.31 ? 639 PRO A CD  1 
ATOM   4675  N N   . LYS A 1 620 ? 154.199 141.717 154.413 1.00 109.12 ? 640 LYS A N   1 
ATOM   4676  C CA  . LYS A 1 620 ? 155.595 141.647 154.015 1.00 114.23 ? 640 LYS A CA  1 
ATOM   4677  C C   . LYS A 1 620 ? 156.225 140.403 154.632 1.00 118.70 ? 640 LYS A C   1 
ATOM   4678  O O   . LYS A 1 620 ? 155.639 139.790 155.520 1.00 121.00 ? 640 LYS A O   1 
ATOM   4679  C CB  . LYS A 1 620 ? 156.353 142.902 154.455 1.00 116.06 ? 640 LYS A CB  1 
ATOM   4680  C CG  . LYS A 1 620 ? 155.751 144.225 154.001 1.00 118.59 ? 640 LYS A CG  1 
ATOM   4681  C CD  . LYS A 1 620 ? 156.796 145.310 153.794 1.00 120.72 ? 640 LYS A CD  1 
ATOM   4682  C CE  . LYS A 1 620 ? 157.718 145.502 154.981 1.00 121.76 ? 640 LYS A CE  1 
ATOM   4683  N NZ  . LYS A 1 620 ? 158.987 146.150 154.580 1.00 121.38 ? 640 LYS A NZ  1 
ATOM   4684  N N   . GLN A 1 621 ? 157.424 140.046 154.159 1.00 123.19 ? 641 GLN A N   1 
ATOM   4685  C CA  . GLN A 1 621 ? 158.100 138.841 154.614 1.00 128.79 ? 641 GLN A CA  1 
ATOM   4686  C C   . GLN A 1 621 ? 158.395 138.944 156.107 1.00 131.62 ? 641 GLN A C   1 
ATOM   4687  O O   . GLN A 1 621 ? 158.109 138.021 156.868 1.00 132.84 ? 641 GLN A O   1 
ATOM   4688  C CB  . GLN A 1 621 ? 159.411 138.596 153.857 1.00 131.50 ? 641 GLN A CB  1 
ATOM   4689  C CG  . GLN A 1 621 ? 159.245 138.137 152.415 1.00 134.59 ? 641 GLN A CG  1 
ATOM   4690  C CD  . GLN A 1 621 ? 158.376 136.912 152.248 1.00 137.29 ? 641 GLN A CD  1 
ATOM   4691  O OE1 . GLN A 1 621 ? 158.147 136.452 151.132 1.00 139.05 ? 641 GLN A OE1 1 
ATOM   4692  N NE2 . GLN A 1 621 ? 157.866 136.378 153.348 1.00 136.13 ? 641 GLN A NE2 1 
ATOM   4693  N N   . ILE A 1 622 ? 158.965 140.087 156.508 1.00 133.64 ? 642 ILE A N   1 
ATOM   4694  C CA  . ILE A 1 622 ? 159.240 140.392 157.903 1.00 136.31 ? 642 ILE A CA  1 
ATOM   4695  C C   . ILE A 1 622 ? 157.954 140.314 158.727 1.00 133.50 ? 642 ILE A C   1 
ATOM   4696  O O   . ILE A 1 622 ? 157.979 139.867 159.870 1.00 134.73 ? 642 ILE A O   1 
ATOM   4697  C CB  . ILE A 1 622 ? 159.940 141.762 158.040 1.00 144.33 ? 642 ILE A CB  1 
ATOM   4698  C CG1 . ILE A 1 622 ? 160.143 142.147 159.510 1.00 149.13 ? 642 ILE A CG1 1 
ATOM   4699  C CG2 . ILE A 1 622 ? 159.202 142.855 157.273 1.00 146.45 ? 642 ILE A CG2 1 
ATOM   4700  C CD1 . ILE A 1 622 ? 161.147 143.260 159.728 1.00 151.11 ? 642 ILE A CD1 1 
ATOM   4701  N N   . TYR A 1 623 ? 156.824 140.720 158.139 1.00 129.60 ? 643 TYR A N   1 
ATOM   4702  C CA  . TYR A 1 623 ? 155.548 140.638 158.833 1.00 126.71 ? 643 TYR A CA  1 
ATOM   4703  C C   . TYR A 1 623 ? 155.049 139.195 158.895 1.00 126.33 ? 643 TYR A C   1 
ATOM   4704  O O   . TYR A 1 623 ? 154.564 138.773 159.941 1.00 128.16 ? 643 TYR A O   1 
ATOM   4705  C CB  . TYR A 1 623 ? 154.533 141.599 158.212 1.00 125.98 ? 643 TYR A CB  1 
ATOM   4706  C CG  . TYR A 1 623 ? 154.674 143.036 158.654 1.00 127.74 ? 643 TYR A CG  1 
ATOM   4707  C CD1 . TYR A 1 623 ? 155.774 143.465 159.386 1.00 128.98 ? 643 TYR A CD1 1 
ATOM   4708  C CD2 . TYR A 1 623 ? 153.690 143.970 158.367 1.00 129.64 ? 643 TYR A CD2 1 
ATOM   4709  C CE1 . TYR A 1 623 ? 155.906 144.783 159.793 1.00 132.30 ? 643 TYR A CE1 1 
ATOM   4710  C CE2 . TYR A 1 623 ? 153.808 145.292 158.767 1.00 131.42 ? 643 TYR A CE2 1 
ATOM   4711  C CZ  . TYR A 1 623 ? 154.918 145.701 159.485 1.00 134.66 ? 643 TYR A CZ  1 
ATOM   4712  O OH  . TYR A 1 623 ? 155.038 147.010 159.889 1.00 137.39 ? 643 TYR A OH  1 
ATOM   4713  N N   . CYS A 1 624 ? 155.178 138.434 157.801 1.00 127.15 ? 644 CYS A N   1 
ATOM   4714  C CA  . CYS A 1 624 ? 154.668 137.070 157.760 1.00 130.26 ? 644 CYS A CA  1 
ATOM   4715  C C   . CYS A 1 624 ? 155.342 136.207 158.819 1.00 129.68 ? 644 CYS A C   1 
ATOM   4716  O O   . CYS A 1 624 ? 154.683 135.614 159.665 1.00 127.04 ? 644 CYS A O   1 
ATOM   4717  C CB  . CYS A 1 624 ? 154.976 136.361 156.451 1.00 135.73 ? 644 CYS A CB  1 
ATOM   4718  S SG  . CYS A 1 624 ? 154.310 137.145 154.965 1.00 145.00 ? 644 CYS A SG  1 
ATOM   4719  N N   . TYR A 1 625 ? 156.675 136.141 158.747 1.00 134.68 ? 645 TYR A N   1 
ATOM   4720  C CA  . TYR A 1 625 ? 157.418 135.189 159.558 1.00 141.10 ? 645 TYR A CA  1 
ATOM   4721  C C   . TYR A 1 625 ? 157.194 135.507 161.035 1.00 133.66 ? 645 TYR A C   1 
ATOM   4722  O O   . TYR A 1 625 ? 156.980 134.599 161.836 1.00 132.67 ? 645 TYR A O   1 
ATOM   4723  C CB  . TYR A 1 625 ? 158.899 135.158 159.164 1.00 150.79 ? 645 TYR A CB  1 
ATOM   4724  C CG  . TYR A 1 625 ? 159.821 136.065 159.937 1.00 162.14 ? 645 TYR A CG  1 
ATOM   4725  C CD1 . TYR A 1 625 ? 159.902 137.416 159.644 1.00 167.94 ? 645 TYR A CD1 1 
ATOM   4726  C CD2 . TYR A 1 625 ? 160.608 135.578 160.969 1.00 168.96 ? 645 TYR A CD2 1 
ATOM   4727  C CE1 . TYR A 1 625 ? 160.749 138.260 160.347 1.00 172.34 ? 645 TYR A CE1 1 
ATOM   4728  C CE2 . TYR A 1 625 ? 161.461 136.406 161.682 1.00 172.40 ? 645 TYR A CE2 1 
ATOM   4729  C CZ  . TYR A 1 625 ? 161.533 137.753 161.371 1.00 173.11 ? 645 TYR A CZ  1 
ATOM   4730  O OH  . TYR A 1 625 ? 162.374 138.580 162.077 1.00 168.42 ? 645 TYR A OH  1 
ATOM   4731  N N   . LEU A 1 626 ? 157.140 136.807 161.356 1.00 126.59 ? 646 LEU A N   1 
ATOM   4732  C CA  . LEU A 1 626 ? 156.899 137.261 162.715 1.00 122.90 ? 646 LEU A CA  1 
ATOM   4733  C C   . LEU A 1 626 ? 155.484 136.909 163.180 1.00 119.00 ? 646 LEU A C   1 
ATOM   4734  O O   . LEU A 1 626 ? 155.316 136.517 164.332 1.00 119.23 ? 646 LEU A O   1 
ATOM   4735  C CB  . LEU A 1 626 ? 157.160 138.767 162.809 1.00 122.28 ? 646 LEU A CB  1 
ATOM   4736  C CG  . LEU A 1 626 ? 157.297 139.336 164.223 1.00 124.30 ? 646 LEU A CG  1 
ATOM   4737  C CD1 . LEU A 1 626 ? 158.500 138.744 164.944 1.00 126.80 ? 646 LEU A CD1 1 
ATOM   4738  C CD2 . LEU A 1 626 ? 157.408 140.852 164.187 1.00 124.33 ? 646 LEU A CD2 1 
ATOM   4739  N N   . GLN A 1 627 ? 154.482 136.994 162.295 1.00 113.16 ? 647 GLN A N   1 
ATOM   4740  C CA  . GLN A 1 627 ? 153.117 136.676 162.694 1.00 108.55 ? 647 GLN A CA  1 
ATOM   4741  C C   . GLN A 1 627 ? 153.013 135.187 163.010 1.00 107.03 ? 647 GLN A C   1 
ATOM   4742  O O   . GLN A 1 627 ? 152.342 134.812 163.968 1.00 107.54 ? 647 GLN A O   1 
ATOM   4743  C CB  . GLN A 1 627 ? 152.090 137.103 161.640 1.00 106.78 ? 647 GLN A CB  1 
ATOM   4744  C CG  . GLN A 1 627 ? 151.885 136.124 160.493 1.00 106.91 ? 647 GLN A CG  1 
ATOM   4745  C CD  . GLN A 1 627 ? 151.111 136.746 159.351 1.00 107.54 ? 647 GLN A CD  1 
ATOM   4746  O OE1 . GLN A 1 627 ? 150.449 137.773 159.497 1.00 105.15 ? 647 GLN A OE1 1 
ATOM   4747  N NE2 . GLN A 1 627 ? 151.169 136.106 158.194 1.00 108.30 ? 647 GLN A NE2 1 
ATOM   4748  N N   . ARG A 1 628 ? 153.702 134.347 162.232 1.00 107.01 ? 648 ARG A N   1 
ATOM   4749  C CA  . ARG A 1 628 ? 153.641 132.909 162.446 1.00 109.67 ? 648 ARG A CA  1 
ATOM   4750  C C   . ARG A 1 628 ? 154.241 132.584 163.814 1.00 108.36 ? 648 ARG A C   1 
ATOM   4751  O O   . ARG A 1 628 ? 153.657 131.824 164.587 1.00 108.18 ? 648 ARG A O   1 
ATOM   4752  C CB  . ARG A 1 628 ? 154.371 132.133 161.345 1.00 113.08 ? 648 ARG A CB  1 
ATOM   4753  C CG  . ARG A 1 628 ? 154.194 132.703 159.946 1.00 116.24 ? 648 ARG A CG  1 
ATOM   4754  C CD  . ARG A 1 628 ? 155.049 131.956 158.947 1.00 119.31 ? 648 ARG A CD  1 
ATOM   4755  N NE  . ARG A 1 628 ? 154.505 130.640 158.642 1.00 122.59 ? 648 ARG A NE  1 
ATOM   4756  C CZ  . ARG A 1 628 ? 155.147 129.686 157.974 1.00 124.73 ? 648 ARG A CZ  1 
ATOM   4757  N NH1 . ARG A 1 628 ? 156.424 129.829 157.662 1.00 125.00 ? 648 ARG A NH1 1 
ATOM   4758  N NH2 . ARG A 1 628 ? 154.511 128.572 157.651 1.00 124.51 ? 648 ARG A NH2 1 
ATOM   4759  N N   . ILE A 1 629 ? 155.398 133.186 164.118 1.00 107.54 ? 649 ILE A N   1 
ATOM   4760  C CA  . ILE A 1 629 ? 156.097 132.889 165.359 1.00 107.14 ? 649 ILE A CA  1 
ATOM   4761  C C   . ILE A 1 629 ? 155.227 133.350 166.528 1.00 103.34 ? 649 ILE A C   1 
ATOM   4762  O O   . ILE A 1 629 ? 155.042 132.610 167.487 1.00 101.99 ? 649 ILE A O   1 
ATOM   4763  C CB  . ILE A 1 629 ? 157.511 133.506 165.408 1.00 111.20 ? 649 ILE A CB  1 
ATOM   4764  C CG1 . ILE A 1 629 ? 158.278 133.343 164.093 1.00 113.34 ? 649 ILE A CG1 1 
ATOM   4765  C CG2 . ILE A 1 629 ? 158.305 132.909 166.559 1.00 112.70 ? 649 ILE A CG2 1 
ATOM   4766  C CD1 . ILE A 1 629 ? 159.454 134.284 163.947 1.00 114.56 ? 649 ILE A CD1 1 
ATOM   4767  N N   . GLY A 1 630 ? 154.675 134.565 166.430 1.00 99.12  ? 650 GLY A N   1 
ATOM   4768  C CA  . GLY A 1 630 ? 153.829 135.122 167.475 1.00 95.91  ? 650 GLY A CA  1 
ATOM   4769  C C   . GLY A 1 630 ? 152.628 134.232 167.780 1.00 91.60  ? 650 GLY A C   1 
ATOM   4770  O O   . GLY A 1 630 ? 152.397 133.879 168.931 1.00 90.83  ? 650 GLY A O   1 
ATOM   4771  N N   . ILE A 1 631 ? 151.884 133.859 166.732 1.00 87.70  ? 651 ILE A N   1 
ATOM   4772  C CA  . ILE A 1 631 ? 150.677 133.061 166.885 1.00 84.88  ? 651 ILE A CA  1 
ATOM   4773  C C   . ILE A 1 631 ? 151.023 131.696 167.472 1.00 84.85  ? 651 ILE A C   1 
ATOM   4774  O O   . ILE A 1 631 ? 150.275 131.188 168.300 1.00 83.21  ? 651 ILE A O   1 
ATOM   4775  C CB  . ILE A 1 631 ? 149.912 132.953 165.548 1.00 84.43  ? 651 ILE A CB  1 
ATOM   4776  C CG1 . ILE A 1 631 ? 148.912 134.099 165.386 1.00 83.05  ? 651 ILE A CG1 1 
ATOM   4777  C CG2 . ILE A 1 631 ? 149.206 131.608 165.405 1.00 83.96  ? 651 ILE A CG2 1 
ATOM   4778  C CD1 . ILE A 1 631 ? 149.491 135.476 165.551 1.00 82.56  ? 651 ILE A CD1 1 
ATOM   4779  N N   . GLY A 1 632 ? 152.139 131.105 167.031 1.00 88.22  ? 652 GLY A N   1 
ATOM   4780  C CA  . GLY A 1 632 ? 152.552 129.790 167.494 1.00 90.68  ? 652 GLY A CA  1 
ATOM   4781  C C   . GLY A 1 632 ? 153.091 129.790 168.927 1.00 91.52  ? 652 GLY A C   1 
ATOM   4782  O O   . GLY A 1 632 ? 152.985 128.779 169.616 1.00 92.17  ? 652 GLY A O   1 
ATOM   4783  N N   . LEU A 1 633 ? 153.657 130.923 169.374 1.00 90.17  ? 653 LEU A N   1 
ATOM   4784  C CA  . LEU A 1 633 ? 154.417 130.936 170.618 1.00 89.90  ? 653 LEU A CA  1 
ATOM   4785  C C   . LEU A 1 633 ? 153.570 131.459 171.780 1.00 89.96  ? 653 LEU A C   1 
ATOM   4786  O O   . LEU A 1 633 ? 153.615 130.886 172.867 1.00 90.53  ? 653 LEU A O   1 
ATOM   4787  C CB  . LEU A 1 633 ? 155.713 131.743 170.443 1.00 90.09  ? 653 LEU A CB  1 
ATOM   4788  C CG  . LEU A 1 633 ? 155.649 133.256 170.673 1.00 90.51  ? 653 LEU A CG  1 
ATOM   4789  C CD1 . LEU A 1 633 ? 155.888 133.617 172.135 1.00 90.73  ? 653 LEU A CD1 1 
ATOM   4790  C CD2 . LEU A 1 633 ? 156.658 133.987 169.804 1.00 91.04  ? 653 LEU A CD2 1 
ATOM   4791  N N   . SER A 1 634 ? 152.811 132.542 171.557 1.00 88.24  ? 654 SER A N   1 
ATOM   4792  C CA  . SER A 1 634 ? 152.158 133.246 172.652 1.00 86.78  ? 654 SER A CA  1 
ATOM   4793  C C   . SER A 1 634 ? 151.252 132.301 173.440 1.00 85.18  ? 654 SER A C   1 
ATOM   4794  O O   . SER A 1 634 ? 151.348 132.247 174.660 1.00 84.87  ? 654 SER A O   1 
ATOM   4795  C CB  . SER A 1 634 ? 151.422 134.480 172.173 1.00 86.64  ? 654 SER A CB  1 
ATOM   4796  O OG  . SER A 1 634 ? 152.289 135.313 171.415 1.00 86.77  ? 654 SER A OG  1 
ATOM   4797  N N   . PRO A 1 635 ? 150.361 131.503 172.812 1.00 87.04  ? 655 PRO A N   1 
ATOM   4798  C CA  . PRO A 1 635 ? 149.561 130.540 173.567 1.00 90.79  ? 655 PRO A CA  1 
ATOM   4799  C C   . PRO A 1 635 ? 150.454 129.548 174.309 1.00 95.65  ? 655 PRO A C   1 
ATOM   4800  O O   . PRO A 1 635 ? 150.185 129.177 175.451 1.00 97.80  ? 655 PRO A O   1 
ATOM   4801  C CB  . PRO A 1 635 ? 148.706 129.834 172.505 1.00 90.22  ? 655 PRO A CB  1 
ATOM   4802  C CG  . PRO A 1 635 ? 148.734 130.768 171.312 1.00 89.80  ? 655 PRO A CG  1 
ATOM   4803  C CD  . PRO A 1 635 ? 150.082 131.456 171.371 1.00 88.49  ? 655 PRO A CD  1 
ATOM   4804  N N   . ALA A 1 636 ? 151.537 129.133 173.646 1.00 97.33  ? 656 ALA A N   1 
ATOM   4805  C CA  . ALA A 1 636 ? 152.464 128.179 174.230 1.00 98.27  ? 656 ALA A CA  1 
ATOM   4806  C C   . ALA A 1 636 ? 153.086 128.785 175.484 1.00 97.12  ? 656 ALA A C   1 
ATOM   4807  O O   . ALA A 1 636 ? 153.071 128.157 176.536 1.00 95.28  ? 656 ALA A O   1 
ATOM   4808  C CB  . ALA A 1 636 ? 153.519 127.773 173.232 1.00 100.33 ? 656 ALA A CB  1 
ATOM   4809  N N   . MET A 1 637 ? 153.598 130.015 175.375 1.00 98.83  ? 657 MET A N   1 
ATOM   4810  C CA  . MET A 1 637 ? 154.317 130.644 176.470 1.00 101.65 ? 657 MET A CA  1 
ATOM   4811  C C   . MET A 1 637 ? 153.377 130.883 177.653 1.00 101.87 ? 657 MET A C   1 
ATOM   4812  O O   . MET A 1 637 ? 153.773 130.678 178.792 1.00 103.79 ? 657 MET A O   1 
ATOM   4813  C CB  . MET A 1 637 ? 154.955 131.963 176.016 1.00 102.33 ? 657 MET A CB  1 
ATOM   4814  C CG  . MET A 1 637 ? 155.332 132.894 177.152 1.00 104.47 ? 657 MET A CG  1 
ATOM   4815  S SD  . MET A 1 637 ? 156.170 134.396 176.588 1.00 108.33 ? 657 MET A SD  1 
ATOM   4816  C CE  . MET A 1 637 ? 157.306 133.709 175.385 1.00 109.50 ? 657 MET A CE  1 
ATOM   4817  N N   . SER A 1 638 ? 152.133 131.300 177.393 1.00 98.88  ? 658 SER A N   1 
ATOM   4818  C CA  . SER A 1 638 ? 151.190 131.512 178.477 1.00 96.77  ? 658 SER A CA  1 
ATOM   4819  C C   . SER A 1 638 ? 150.827 130.179 179.128 1.00 96.59  ? 658 SER A C   1 
ATOM   4820  O O   . SER A 1 638 ? 151.054 129.993 180.322 1.00 98.37  ? 658 SER A O   1 
ATOM   4821  C CB  . SER A 1 638 ? 149.977 132.263 178.003 1.00 97.08  ? 658 SER A CB  1 
ATOM   4822  O OG  . SER A 1 638 ? 150.313 133.612 177.735 1.00 97.03  ? 658 SER A OG  1 
ATOM   4823  N N   . TYR A 1 639 ? 150.272 129.257 178.336 1.00 96.04  ? 659 TYR A N   1 
ATOM   4824  C CA  . TYR A 1 639 ? 149.632 128.072 178.882 1.00 98.46  ? 659 TYR A CA  1 
ATOM   4825  C C   . TYR A 1 639 ? 150.659 127.058 179.393 1.00 101.48 ? 659 TYR A C   1 
ATOM   4826  O O   . TYR A 1 639 ? 150.318 126.242 180.246 1.00 103.18 ? 659 TYR A O   1 
ATOM   4827  C CB  . TYR A 1 639 ? 148.715 127.428 177.842 1.00 98.03  ? 659 TYR A CB  1 
ATOM   4828  C CG  . TYR A 1 639 ? 147.721 128.347 177.180 1.00 97.29  ? 659 TYR A CG  1 
ATOM   4829  C CD1 . TYR A 1 639 ? 147.242 129.499 177.786 1.00 96.75  ? 659 TYR A CD1 1 
ATOM   4830  C CD2 . TYR A 1 639 ? 147.295 128.070 175.895 1.00 98.63  ? 659 TYR A CD2 1 
ATOM   4831  C CE1 . TYR A 1 639 ? 146.334 130.327 177.145 1.00 95.78  ? 659 TYR A CE1 1 
ATOM   4832  C CE2 . TYR A 1 639 ? 146.369 128.874 175.248 1.00 98.61  ? 659 TYR A CE2 1 
ATOM   4833  C CZ  . TYR A 1 639 ? 145.901 130.017 175.867 1.00 96.14  ? 659 TYR A CZ  1 
ATOM   4834  O OH  . TYR A 1 639 ? 145.010 130.814 175.192 1.00 93.84  ? 659 TYR A OH  1 
ATOM   4835  N N   . SER A 1 640 ? 151.906 127.119 178.904 1.00 101.38 ? 660 SER A N   1 
ATOM   4836  C CA  . SER A 1 640 ? 152.945 126.209 179.358 1.00 102.15 ? 660 SER A CA  1 
ATOM   4837  C C   . SER A 1 640 ? 153.289 126.468 180.823 1.00 101.41 ? 660 SER A C   1 
ATOM   4838  O O   . SER A 1 640 ? 153.524 125.527 181.574 1.00 101.99 ? 660 SER A O   1 
ATOM   4839  C CB  . SER A 1 640 ? 154.174 126.310 178.496 1.00 104.38 ? 660 SER A CB  1 
ATOM   4840  O OG  . SER A 1 640 ? 154.710 127.623 178.536 1.00 103.72 ? 660 SER A OG  1 
ATOM   4841  N N   . ALA A 1 641 ? 153.378 127.745 181.202 1.00 102.07 ? 661 ALA A N   1 
ATOM   4842  C CA  . ALA A 1 641 ? 153.588 128.100 182.594 1.00 103.77 ? 661 ALA A CA  1 
ATOM   4843  C C   . ALA A 1 641 ? 152.291 127.915 183.380 1.00 103.52 ? 661 ALA A C   1 
ATOM   4844  O O   . ALA A 1 641 ? 152.330 127.565 184.555 1.00 104.69 ? 661 ALA A O   1 
ATOM   4845  C CB  . ALA A 1 641 ? 154.111 129.508 182.706 1.00 104.11 ? 661 ALA A CB  1 
ATOM   4846  N N   . LEU A 1 642 ? 151.145 128.171 182.745 1.00 102.92 ? 662 LEU A N   1 
ATOM   4847  C CA  . LEU A 1 642 ? 149.871 128.058 183.433 1.00 103.20 ? 662 LEU A CA  1 
ATOM   4848  C C   . LEU A 1 642 ? 149.623 126.618 183.873 1.00 107.30 ? 662 LEU A C   1 
ATOM   4849  O O   . LEU A 1 642 ? 149.176 126.393 184.997 1.00 108.82 ? 662 LEU A O   1 
ATOM   4850  C CB  . LEU A 1 642 ? 148.752 128.563 182.520 1.00 101.41 ? 662 LEU A CB  1 
ATOM   4851  C CG  . LEU A 1 642 ? 147.414 128.827 183.209 1.00 101.41 ? 662 LEU A CG  1 
ATOM   4852  C CD1 . LEU A 1 642 ? 147.590 129.651 184.477 1.00 101.16 ? 662 LEU A CD1 1 
ATOM   4853  C CD2 . LEU A 1 642 ? 146.463 129.539 182.257 1.00 101.71 ? 662 LEU A CD2 1 
ATOM   4854  N N   . VAL A 1 643 ? 149.942 125.651 182.998 1.00 111.67 ? 663 VAL A N   1 
ATOM   4855  C CA  . VAL A 1 643 ? 149.727 124.244 183.302 1.00 116.80 ? 663 VAL A CA  1 
ATOM   4856  C C   . VAL A 1 643 ? 150.581 123.827 184.499 1.00 118.50 ? 663 VAL A C   1 
ATOM   4857  O O   . VAL A 1 643 ? 150.095 123.131 185.390 1.00 119.28 ? 663 VAL A O   1 
ATOM   4858  C CB  . VAL A 1 643 ? 149.990 123.311 182.101 1.00 118.78 ? 663 VAL A CB  1 
ATOM   4859  C CG1 . VAL A 1 643 ? 148.862 123.355 181.089 1.00 120.45 ? 663 VAL A CG1 1 
ATOM   4860  C CG2 . VAL A 1 643 ? 151.334 123.551 181.429 1.00 117.75 ? 663 VAL A CG2 1 
ATOM   4861  N N   . THR A 1 644 ? 151.844 124.268 184.531 1.00 120.60 ? 664 THR A N   1 
ATOM   4862  C CA  . THR A 1 644 ? 152.735 123.872 185.610 1.00 124.74 ? 664 THR A CA  1 
ATOM   4863  C C   . THR A 1 644 ? 152.291 124.528 186.914 1.00 124.78 ? 664 THR A C   1 
ATOM   4864  O O   . THR A 1 644 ? 152.430 123.916 187.964 1.00 123.70 ? 664 THR A O   1 
ATOM   4865  C CB  . THR A 1 644 ? 154.210 124.151 185.288 1.00 127.74 ? 664 THR A CB  1 
ATOM   4866  O OG1 . THR A 1 644 ? 155.002 123.635 186.360 1.00 131.25 ? 664 THR A OG1 1 
ATOM   4867  C CG2 . THR A 1 644 ? 154.523 125.616 185.093 1.00 126.14 ? 664 THR A CG2 1 
ATOM   4868  N N   . LYS A 1 645 ? 151.766 125.758 186.847 1.00 126.47 ? 665 LYS A N   1 
ATOM   4869  C CA  . LYS A 1 645 ? 151.260 126.437 188.030 1.00 129.33 ? 665 LYS A CA  1 
ATOM   4870  C C   . LYS A 1 645 ? 150.091 125.638 188.608 1.00 132.44 ? 665 LYS A C   1 
ATOM   4871  O O   . LYS A 1 645 ? 150.056 125.345 189.811 1.00 134.19 ? 665 LYS A O   1 
ATOM   4872  C CB  . LYS A 1 645 ? 150.860 127.871 187.673 1.00 130.06 ? 665 LYS A CB  1 
ATOM   4873  C CG  . LYS A 1 645 ? 150.450 128.764 188.836 1.00 131.47 ? 665 LYS A CG  1 
ATOM   4874  C CD  . LYS A 1 645 ? 150.190 130.191 188.415 1.00 132.52 ? 665 LYS A CD  1 
ATOM   4875  C CE  . LYS A 1 645 ? 149.261 130.926 189.357 1.00 132.95 ? 665 LYS A CE  1 
ATOM   4876  N NZ  . LYS A 1 645 ? 149.558 132.376 189.390 1.00 132.72 ? 665 LYS A NZ  1 
ATOM   4877  N N   . THR A 1 646 ? 149.138 125.277 187.740 1.00 136.13 ? 666 THR A N   1 
ATOM   4878  C CA  . THR A 1 646 ? 147.970 124.530 188.180 1.00 140.88 ? 666 THR A CA  1 
ATOM   4879  C C   . THR A 1 646 ? 148.402 123.155 188.692 1.00 145.26 ? 666 THR A C   1 
ATOM   4880  O O   . THR A 1 646 ? 147.809 122.624 189.631 1.00 146.84 ? 666 THR A O   1 
ATOM   4881  C CB  . THR A 1 646 ? 146.916 124.428 187.070 1.00 141.50 ? 666 THR A CB  1 
ATOM   4882  O OG1 . THR A 1 646 ? 147.517 123.817 185.930 1.00 142.75 ? 666 THR A OG1 1 
ATOM   4883  C CG2 . THR A 1 646 ? 146.341 125.770 186.672 1.00 140.70 ? 666 THR A CG2 1 
ATOM   4884  N N   . ASN A 1 647 ? 149.448 122.592 188.074 1.00 148.50 ? 667 ASN A N   1 
ATOM   4885  C CA  . ASN A 1 647 ? 149.964 121.290 188.455 1.00 154.04 ? 667 ASN A CA  1 
ATOM   4886  C C   . ASN A 1 647 ? 150.571 121.354 189.851 1.00 157.12 ? 667 ASN A C   1 
ATOM   4887  O O   . ASN A 1 647 ? 150.350 120.444 190.636 1.00 158.73 ? 667 ASN A O   1 
ATOM   4888  C CB  . ASN A 1 647 ? 150.954 120.757 187.419 1.00 156.07 ? 667 ASN A CB  1 
ATOM   4889  C CG  . ASN A 1 647 ? 150.266 120.392 186.120 1.00 158.34 ? 667 ASN A CG  1 
ATOM   4890  O OD1 . ASN A 1 647 ? 149.065 120.602 185.967 1.00 158.21 ? 667 ASN A OD1 1 
ATOM   4891  N ND2 . ASN A 1 647 ? 151.003 119.826 185.179 1.00 160.36 ? 667 ASN A ND2 1 
ATOM   4892  N N   . ARG A 1 648 ? 151.324 122.417 190.162 1.00 158.14 ? 668 ARG A N   1 
ATOM   4893  C CA  . ARG A 1 648 ? 151.940 122.531 191.476 1.00 160.15 ? 668 ARG A CA  1 
ATOM   4894  C C   . ARG A 1 648 ? 150.843 122.632 192.532 1.00 159.03 ? 668 ARG A C   1 
ATOM   4895  O O   . ARG A 1 648 ? 150.937 121.995 193.582 1.00 160.66 ? 668 ARG A O   1 
ATOM   4896  C CB  . ARG A 1 648 ? 152.935 123.696 191.558 1.00 163.07 ? 668 ARG A CB  1 
ATOM   4897  C CG  . ARG A 1 648 ? 152.328 125.087 191.697 1.00 166.84 ? 668 ARG A CG  1 
ATOM   4898  C CD  . ARG A 1 648 ? 153.353 126.193 191.821 1.00 169.74 ? 668 ARG A CD  1 
ATOM   4899  N NE  . ARG A 1 648 ? 154.093 126.110 193.072 1.00 171.44 ? 668 ARG A NE  1 
ATOM   4900  C CZ  . ARG A 1 648 ? 155.289 125.549 193.223 1.00 172.19 ? 668 ARG A CZ  1 
ATOM   4901  N NH1 . ARG A 1 648 ? 155.871 124.914 192.221 1.00 171.89 ? 668 ARG A NH1 1 
ATOM   4902  N NH2 . ARG A 1 648 ? 155.892 125.596 194.400 1.00 172.77 ? 668 ARG A NH2 1 
ATOM   4903  N N   . ILE A 1 649 ? 149.797 123.413 192.234 1.00 158.36 ? 669 ILE A N   1 
ATOM   4904  C CA  . ILE A 1 649 ? 148.693 123.583 193.162 1.00 159.55 ? 669 ILE A CA  1 
ATOM   4905  C C   . ILE A 1 649 ? 147.995 122.237 193.366 1.00 160.89 ? 669 ILE A C   1 
ATOM   4906  O O   . ILE A 1 649 ? 147.714 121.847 194.499 1.00 161.36 ? 669 ILE A O   1 
ATOM   4907  C CB  . ILE A 1 649 ? 147.720 124.679 192.680 1.00 159.18 ? 669 ILE A CB  1 
ATOM   4908  C CG1 . ILE A 1 649 ? 148.405 126.043 192.543 1.00 158.65 ? 669 ILE A CG1 1 
ATOM   4909  C CG2 . ILE A 1 649 ? 146.509 124.753 193.596 1.00 159.22 ? 669 ILE A CG2 1 
ATOM   4910  C CD1 . ILE A 1 649 ? 149.135 126.504 193.784 1.00 158.45 ? 669 ILE A CD1 1 
ATOM   4911  N N   . ALA A 1 650 ? 147.737 121.525 192.263 1.00 162.39 ? 670 ALA A N   1 
ATOM   4912  C CA  . ALA A 1 650 ? 147.017 120.263 192.321 1.00 166.50 ? 670 ALA A CA  1 
ATOM   4913  C C   . ALA A 1 650 ? 147.840 119.198 193.047 1.00 171.99 ? 670 ALA A C   1 
ATOM   4914  O O   . ALA A 1 650 ? 147.267 118.331 193.706 1.00 172.54 ? 670 ALA A O   1 
ATOM   4915  C CB  . ALA A 1 650 ? 146.642 119.816 190.928 1.00 166.81 ? 670 ALA A CB  1 
ATOM   4916  N N   . ARG A 1 651 ? 149.173 119.260 192.923 1.00 178.19 ? 671 ARG A N   1 
ATOM   4917  C CA  . ARG A 1 651 ? 150.037 118.268 193.543 1.00 183.17 ? 671 ARG A CA  1 
ATOM   4918  C C   . ARG A 1 651 ? 150.096 118.506 195.049 1.00 184.77 ? 671 ARG A C   1 
ATOM   4919  O O   . ARG A 1 651 ? 150.015 117.552 195.824 1.00 185.25 ? 671 ARG A O   1 
ATOM   4920  C CB  . ARG A 1 651 ? 151.441 118.272 192.928 1.00 184.98 ? 671 ARG A CB  1 
ATOM   4921  C CG  . ARG A 1 651 ? 151.512 117.777 191.488 1.00 187.62 ? 671 ARG A CG  1 
ATOM   4922  C CD  . ARG A 1 651 ? 150.642 116.570 191.179 1.00 189.39 ? 671 ARG A CD  1 
ATOM   4923  N NE  . ARG A 1 651 ? 150.944 115.423 192.024 1.00 191.13 ? 671 ARG A NE  1 
ATOM   4924  C CZ  . ARG A 1 651 ? 152.041 114.674 191.937 1.00 192.15 ? 671 ARG A CZ  1 
ATOM   4925  N NH1 . ARG A 1 651 ? 152.957 114.923 191.017 1.00 191.22 ? 671 ARG A NH1 1 
ATOM   4926  N NH2 . ARG A 1 651 ? 152.214 113.662 192.772 1.00 192.66 ? 671 ARG A NH2 1 
ATOM   4927  N N   . ILE A 1 652 ? 150.232 119.769 195.467 1.00 187.16 ? 672 ILE A N   1 
ATOM   4928  C CA  . ILE A 1 652 ? 150.255 120.067 196.892 1.00 190.12 ? 672 ILE A CA  1 
ATOM   4929  C C   . ILE A 1 652 ? 148.891 119.728 197.493 1.00 194.50 ? 672 ILE A C   1 
ATOM   4930  O O   . ILE A 1 652 ? 148.827 119.368 198.666 1.00 193.11 ? 672 ILE A O   1 
ATOM   4931  C CB  . ILE A 1 652 ? 150.717 121.511 197.184 1.00 188.43 ? 672 ILE A CB  1 
ATOM   4932  C CG1 . ILE A 1 652 ? 149.758 122.568 196.634 1.00 186.63 ? 672 ILE A CG1 1 
ATOM   4933  C CG2 . ILE A 1 652 ? 152.142 121.728 196.694 1.00 188.81 ? 672 ILE A CG2 1 
ATOM   4934  C CD1 . ILE A 1 652 ? 148.723 123.039 197.632 1.00 186.67 ? 672 ILE A CD1 1 
ATOM   4935  N N   . LEU A 1 653 ? 147.816 119.803 196.693 1.00 199.80 ? 673 LEU A N   1 
ATOM   4936  C CA  . LEU A 1 653 ? 146.503 119.350 197.139 1.00 205.61 ? 673 LEU A CA  1 
ATOM   4937  C C   . LEU A 1 653 ? 146.470 117.825 197.242 1.00 209.88 ? 673 LEU A C   1 
ATOM   4938  O O   . LEU A 1 653 ? 145.909 117.285 198.196 1.00 208.29 ? 673 LEU A O   1 
ATOM   4939  C CB  . LEU A 1 653 ? 145.424 119.859 196.174 1.00 205.86 ? 673 LEU A CB  1 
ATOM   4940  C CG  . LEU A 1 653 ? 144.111 119.075 196.169 1.00 206.61 ? 673 LEU A CG  1 
ATOM   4941  C CD1 . LEU A 1 653 ? 143.210 119.506 197.317 1.00 205.34 ? 673 LEU A CD1 1 
ATOM   4942  C CD2 . LEU A 1 653 ? 143.405 119.214 194.829 1.00 206.78 ? 673 LEU A CD2 1 
ATOM   4943  N N   . ALA A 1 654 ? 147.055 117.138 196.250 1.00 214.87 ? 674 ALA A N   1 
ATOM   4944  C CA  . ALA A 1 654 ? 147.023 115.683 196.192 1.00 220.72 ? 674 ALA A CA  1 
ATOM   4945  C C   . ALA A 1 654 ? 147.757 115.085 197.391 1.00 227.53 ? 674 ALA A C   1 
ATOM   4946  O O   . ALA A 1 654 ? 147.412 113.995 197.847 1.00 229.89 ? 674 ALA A O   1 
ATOM   4947  C CB  . ALA A 1 654 ? 147.613 115.196 194.889 1.00 219.49 ? 674 ALA A CB  1 
ATOM   4948  N N   . GLY A 1 655 ? 148.774 115.799 197.890 1.00 229.68 ? 675 GLY A N   1 
ATOM   4949  C CA  . GLY A 1 655 ? 149.446 115.423 199.124 1.00 230.44 ? 675 GLY A CA  1 
ATOM   4950  C C   . GLY A 1 655 ? 148.501 115.435 200.316 1.00 230.27 ? 675 GLY A C   1 
ATOM   4951  O O   . GLY A 1 655 ? 148.524 114.442 201.079 1.00 228.37 ? 675 GLY A O   1 
ATOM   4952  N N   . MET A 1 668 ? 161.796 118.053 193.794 1.00 199.62 ? 688 MET A N   1 
ATOM   4953  C CA  . MET A 1 668 ? 161.341 118.634 192.500 1.00 200.17 ? 688 MET A CA  1 
ATOM   4954  C C   . MET A 1 668 ? 160.747 120.019 192.743 1.00 199.79 ? 688 MET A C   1 
ATOM   4955  O O   . MET A 1 668 ? 160.633 120.442 193.893 1.00 200.03 ? 688 MET A O   1 
ATOM   4956  C CB  . MET A 1 668 ? 160.282 117.754 191.828 1.00 199.94 ? 688 MET A CB  1 
ATOM   4957  C CG  . MET A 1 668 ? 160.572 117.476 190.365 1.00 200.48 ? 688 MET A CG  1 
ATOM   4958  S SD  . MET A 1 668 ? 159.170 116.694 189.528 1.00 198.66 ? 688 MET A SD  1 
ATOM   4959  C CE  . MET A 1 668 ? 159.942 116.134 188.010 1.00 197.25 ? 688 MET A CE  1 
ATOM   4960  N N   . SER A 1 669 ? 160.382 120.699 191.639 1.00 196.99 ? 689 SER A N   1 
ATOM   4961  C CA  . SER A 1 669 ? 159.648 121.967 191.610 1.00 194.57 ? 689 SER A CA  1 
ATOM   4962  C C   . SER A 1 669 ? 160.568 123.198 191.631 1.00 192.56 ? 689 SER A C   1 
ATOM   4963  O O   . SER A 1 669 ? 161.783 123.087 191.467 1.00 189.60 ? 689 SER A O   1 
ATOM   4964  C CB  . SER A 1 669 ? 158.586 122.052 192.700 1.00 193.78 ? 689 SER A CB  1 
ATOM   4965  O OG  . SER A 1 669 ? 159.026 122.811 193.821 1.00 192.09 ? 689 SER A OG  1 
ATOM   4966  N N   . ALA A 1 670 ? 159.947 124.372 191.841 1.00 191.82 ? 690 ALA A N   1 
ATOM   4967  C CA  . ALA A 1 670 ? 160.603 125.675 191.797 1.00 189.80 ? 690 ALA A CA  1 
ATOM   4968  C C   . ALA A 1 670 ? 161.408 125.820 190.505 1.00 188.68 ? 690 ALA A C   1 
ATOM   4969  O O   . ALA A 1 670 ? 160.834 126.075 189.448 1.00 185.37 ? 690 ALA A O   1 
ATOM   4970  C CB  . ALA A 1 670 ? 161.442 125.896 193.036 1.00 188.67 ? 690 ALA A CB  1 
ATOM   4971  N N   . CYS A 1 671 ? 162.731 125.628 190.596 1.00 189.64 ? 691 CYS A N   1 
ATOM   4972  C CA  . CYS A 1 671 ? 163.598 125.656 189.430 1.00 189.47 ? 691 CYS A CA  1 
ATOM   4973  C C   . CYS A 1 671 ? 163.194 124.548 188.459 1.00 187.39 ? 691 CYS A C   1 
ATOM   4974  O O   . CYS A 1 671 ? 163.153 124.763 187.249 1.00 185.65 ? 691 CYS A O   1 
ATOM   4975  C CB  . CYS A 1 671 ? 165.057 125.493 189.839 1.00 190.38 ? 691 CYS A CB  1 
ATOM   4976  S SG  . CYS A 1 671 ? 165.616 126.734 191.036 1.00 189.17 ? 691 CYS A SG  1 
ATOM   4977  N N   . ALA A 1 672 ? 162.871 123.368 189.009 1.00 187.02 ? 692 ALA A N   1 
ATOM   4978  C CA  . ALA A 1 672 ? 162.461 122.222 188.212 1.00 187.47 ? 692 ALA A CA  1 
ATOM   4979  C C   . ALA A 1 672 ? 161.158 122.526 187.471 1.00 187.61 ? 692 ALA A C   1 
ATOM   4980  O O   . ALA A 1 672 ? 160.997 122.139 186.318 1.00 190.03 ? 692 ALA A O   1 
ATOM   4981  C CB  . ALA A 1 672 ? 162.320 121.002 189.090 1.00 187.13 ? 692 ALA A CB  1 
ATOM   4982  N N   . GLN A 1 673 ? 160.248 123.250 188.133 1.00 182.66 ? 693 GLN A N   1 
ATOM   4983  C CA  . GLN A 1 673 ? 158.994 123.675 187.526 1.00 177.21 ? 693 GLN A CA  1 
ATOM   4984  C C   . GLN A 1 673 ? 159.282 124.546 186.302 1.00 171.47 ? 693 GLN A C   1 
ATOM   4985  O O   . GLN A 1 673 ? 158.656 124.395 185.244 1.00 169.08 ? 693 GLN A O   1 
ATOM   4986  C CB  . GLN A 1 673 ? 158.155 124.420 188.570 1.00 176.70 ? 693 GLN A CB  1 
ATOM   4987  C CG  . GLN A 1 673 ? 157.125 125.383 187.997 1.00 176.40 ? 693 GLN A CG  1 
ATOM   4988  C CD  . GLN A 1 673 ? 156.292 126.015 189.084 1.00 175.93 ? 693 GLN A CD  1 
ATOM   4989  O OE1 . GLN A 1 673 ? 155.110 125.714 189.235 1.00 175.71 ? 693 GLN A OE1 1 
ATOM   4990  N NE2 . GLN A 1 673 ? 156.907 126.890 189.866 1.00 175.01 ? 693 GLN A NE2 1 
ATOM   4991  N N   . LEU A 1 674 ? 160.217 125.490 186.468 1.00 168.81 ? 694 LEU A N   1 
ATOM   4992  C CA  . LEU A 1 674 ? 160.590 126.381 185.382 1.00 169.15 ? 694 LEU A CA  1 
ATOM   4993  C C   . LEU A 1 674 ? 161.176 125.576 184.224 1.00 170.77 ? 694 LEU A C   1 
ATOM   4994  O O   . LEU A 1 674 ? 160.885 125.895 183.074 1.00 170.89 ? 694 LEU A O   1 
ATOM   4995  C CB  . LEU A 1 674 ? 161.574 127.450 185.869 1.00 168.20 ? 694 LEU A CB  1 
ATOM   4996  C CG  . LEU A 1 674 ? 160.957 128.815 186.166 1.00 166.70 ? 694 LEU A CG  1 
ATOM   4997  C CD1 . LEU A 1 674 ? 160.249 128.812 187.509 1.00 166.56 ? 694 LEU A CD1 1 
ATOM   4998  C CD2 . LEU A 1 674 ? 162.015 129.906 186.112 1.00 166.51 ? 694 LEU A CD2 1 
ATOM   4999  N N   . VAL A 1 675 ? 161.975 124.540 184.521 1.00 175.05 ? 695 VAL A N   1 
ATOM   5000  C CA  . VAL A 1 675 ? 162.625 123.791 183.457 1.00 179.86 ? 695 VAL A CA  1 
ATOM   5001  C C   . VAL A 1 675 ? 161.593 122.935 182.725 1.00 179.43 ? 695 VAL A C   1 
ATOM   5002  O O   . VAL A 1 675 ? 161.742 122.731 181.526 1.00 179.66 ? 695 VAL A O   1 
ATOM   5003  C CB  . VAL A 1 675 ? 163.833 122.958 183.936 1.00 184.25 ? 695 VAL A CB  1 
ATOM   5004  C CG1 . VAL A 1 675 ? 164.807 123.792 184.756 1.00 185.41 ? 695 VAL A CG1 1 
ATOM   5005  C CG2 . VAL A 1 675 ? 163.432 121.699 184.687 1.00 185.12 ? 695 VAL A CG2 1 
ATOM   5006  N N   . ILE A 1 676 ? 160.542 122.467 183.411 1.00 178.88 ? 696 ILE A N   1 
ATOM   5007  C CA  . ILE A 1 676 ? 159.500 121.686 182.753 1.00 180.23 ? 696 ILE A CA  1 
ATOM   5008  C C   . ILE A 1 676 ? 158.747 122.598 181.785 1.00 176.93 ? 696 ILE A C   1 
ATOM   5009  O O   . ILE A 1 676 ? 158.498 122.224 180.637 1.00 176.37 ? 696 ILE A O   1 
ATOM   5010  C CB  . ILE A 1 676 ? 158.531 121.038 183.771 1.00 183.17 ? 696 ILE A CB  1 
ATOM   5011  C CG1 . ILE A 1 676 ? 159.248 120.205 184.838 1.00 183.90 ? 696 ILE A CG1 1 
ATOM   5012  C CG2 . ILE A 1 676 ? 157.466 120.200 183.076 1.00 183.20 ? 696 ILE A CG2 1 
ATOM   5013  C CD1 . ILE A 1 676 ? 158.438 120.030 186.105 1.00 183.04 ? 696 ILE A CD1 1 
ATOM   5014  N N   . ALA A 1 677 ? 158.396 123.805 182.250 1.00 175.59 ? 697 ALA A N   1 
ATOM   5015  C CA  . ALA A 1 677 ? 157.728 124.772 181.393 1.00 176.83 ? 697 ALA A CA  1 
ATOM   5016  C C   . ALA A 1 677 ? 158.618 125.101 180.193 1.00 177.72 ? 697 ALA A C   1 
ATOM   5017  O O   . ALA A 1 677 ? 158.133 125.215 179.067 1.00 175.03 ? 697 ALA A O   1 
ATOM   5018  C CB  . ALA A 1 677 ? 157.371 126.010 182.181 1.00 176.41 ? 697 ALA A CB  1 
ATOM   5019  N N   . PHE A 1 678 ? 159.928 125.223 180.444 1.00 179.15 ? 698 PHE A N   1 
ATOM   5020  C CA  . PHE A 1 678 ? 160.866 125.626 179.410 1.00 180.48 ? 698 PHE A CA  1 
ATOM   5021  C C   . PHE A 1 678 ? 161.050 124.524 178.372 1.00 179.19 ? 698 PHE A C   1 
ATOM   5022  O O   . PHE A 1 678 ? 161.181 124.837 177.193 1.00 178.23 ? 698 PHE A O   1 
ATOM   5023  C CB  . PHE A 1 678 ? 162.203 126.074 180.003 1.00 185.31 ? 698 PHE A CB  1 
ATOM   5024  C CG  . PHE A 1 678 ? 162.295 127.567 180.195 1.00 190.66 ? 698 PHE A CG  1 
ATOM   5025  C CD1 . PHE A 1 678 ? 162.169 128.427 179.111 1.00 191.30 ? 698 PHE A CD1 1 
ATOM   5026  C CD2 . PHE A 1 678 ? 162.483 128.115 181.454 1.00 194.00 ? 698 PHE A CD2 1 
ATOM   5027  C CE1 . PHE A 1 678 ? 162.248 129.801 179.284 1.00 191.71 ? 698 PHE A CE1 1 
ATOM   5028  C CE2 . PHE A 1 678 ? 162.563 129.489 181.624 1.00 194.44 ? 698 PHE A CE2 1 
ATOM   5029  C CZ  . PHE A 1 678 ? 162.444 130.330 180.540 1.00 192.89 ? 698 PHE A CZ  1 
ATOM   5030  N N   . ILE A 1 679 ? 161.062 123.254 178.792 1.00 179.89 ? 699 ILE A N   1 
ATOM   5031  C CA  . ILE A 1 679 ? 161.209 122.164 177.835 1.00 181.52 ? 699 ILE A CA  1 
ATOM   5032  C C   . ILE A 1 679 ? 159.936 122.048 177.000 1.00 180.05 ? 699 ILE A C   1 
ATOM   5033  O O   . ILE A 1 679 ? 160.015 121.714 175.819 1.00 178.45 ? 699 ILE A O   1 
ATOM   5034  C CB  . ILE A 1 679 ? 161.594 120.826 178.502 1.00 185.28 ? 699 ILE A CB  1 
ATOM   5035  C CG1 . ILE A 1 679 ? 160.537 120.337 179.499 1.00 185.96 ? 699 ILE A CG1 1 
ATOM   5036  C CG2 . ILE A 1 679 ? 162.977 120.934 179.129 1.00 186.93 ? 699 ILE A CG2 1 
ATOM   5037  C CD1 . ILE A 1 679 ? 160.847 119.006 180.148 1.00 185.40 ? 699 ILE A CD1 1 
ATOM   5038  N N   . LEU A 1 680 ? 158.775 122.341 177.606 1.00 179.58 ? 700 LEU A N   1 
ATOM   5039  C CA  . LEU A 1 680 ? 157.524 122.346 176.864 1.00 178.25 ? 700 LEU A CA  1 
ATOM   5040  C C   . LEU A 1 680 ? 157.584 123.418 175.777 1.00 176.29 ? 700 LEU A C   1 
ATOM   5041  O O   . LEU A 1 680 ? 157.282 123.142 174.614 1.00 175.03 ? 700 LEU A O   1 
ATOM   5042  C CB  . LEU A 1 680 ? 156.335 122.572 177.807 1.00 176.73 ? 700 LEU A CB  1 
ATOM   5043  C CG  . LEU A 1 680 ? 155.582 121.321 178.269 1.00 177.45 ? 700 LEU A CG  1 
ATOM   5044  C CD1 . LEU A 1 680 ? 154.873 120.638 177.107 1.00 177.04 ? 700 LEU A CD1 1 
ATOM   5045  C CD2 . LEU A 1 680 ? 156.512 120.342 178.970 1.00 178.47 ? 700 LEU A CD2 1 
ATOM   5046  N N   . ILE A 1 681 ? 158.001 124.634 176.148 1.00 174.51 ? 701 ILE A N   1 
ATOM   5047  C CA  . ILE A 1 681 ? 158.067 125.713 175.177 1.00 173.80 ? 701 ILE A CA  1 
ATOM   5048  C C   . ILE A 1 681 ? 159.158 125.409 174.152 1.00 177.34 ? 701 ILE A C   1 
ATOM   5049  O O   . ILE A 1 681 ? 159.026 125.801 172.994 1.00 174.84 ? 701 ILE A O   1 
ATOM   5050  C CB  . ILE A 1 681 ? 158.245 127.086 175.854 1.00 172.95 ? 701 ILE A CB  1 
ATOM   5051  C CG1 . ILE A 1 681 ? 157.920 128.224 174.884 1.00 172.28 ? 701 ILE A CG1 1 
ATOM   5052  C CG2 . ILE A 1 681 ? 159.628 127.248 176.463 1.00 174.52 ? 701 ILE A CG2 1 
ATOM   5053  C CD1 . ILE A 1 681 ? 157.557 129.516 175.570 1.00 170.94 ? 701 ILE A CD1 1 
ATOM   5054  N N   . CYS A 1 682 ? 160.212 124.697 174.574 1.00 184.30 ? 702 CYS A N   1 
ATOM   5055  C CA  . CYS A 1 682 ? 161.305 124.339 173.682 1.00 190.86 ? 702 CYS A CA  1 
ATOM   5056  C C   . CYS A 1 682 ? 160.821 123.401 172.579 1.00 188.34 ? 702 CYS A C   1 
ATOM   5057  O O   . CYS A 1 682 ? 161.158 123.603 171.414 1.00 189.56 ? 702 CYS A O   1 
ATOM   5058  C CB  . CYS A 1 682 ? 162.470 123.710 174.440 1.00 196.61 ? 702 CYS A CB  1 
ATOM   5059  S SG  . CYS A 1 682 ? 163.545 124.926 175.247 1.00 203.35 ? 702 CYS A SG  1 
ATOM   5060  N N   . ILE A 1 683 ? 160.036 122.379 172.941 1.00 182.56 ? 703 ILE A N   1 
ATOM   5061  C CA  . ILE A 1 683 ? 159.553 121.433 171.946 1.00 179.72 ? 703 ILE A CA  1 
ATOM   5062  C C   . ILE A 1 683 ? 158.576 122.150 171.017 1.00 175.50 ? 703 ILE A C   1 
ATOM   5063  O O   . ILE A 1 683 ? 158.562 121.889 169.817 1.00 174.53 ? 703 ILE A O   1 
ATOM   5064  C CB  . ILE A 1 683 ? 158.952 120.158 172.577 1.00 181.12 ? 703 ILE A CB  1 
ATOM   5065  C CG1 . ILE A 1 683 ? 157.733 120.437 173.461 1.00 179.34 ? 703 ILE A CG1 1 
ATOM   5066  C CG2 . ILE A 1 683 ? 160.029 119.384 173.328 1.00 182.93 ? 703 ILE A CG2 1 
ATOM   5067  C CD1 . ILE A 1 683 ? 156.980 119.191 173.877 1.00 179.20 ? 703 ILE A CD1 1 
ATOM   5068  N N   . GLN A 1 684 ? 157.784 123.074 171.568 1.00 172.59 ? 704 GLN A N   1 
ATOM   5069  C CA  . GLN A 1 684 ? 156.857 123.849 170.760 1.00 170.18 ? 704 GLN A CA  1 
ATOM   5070  C C   . GLN A 1 684 ? 157.630 124.673 169.728 1.00 168.10 ? 704 GLN A C   1 
ATOM   5071  O O   . GLN A 1 684 ? 157.284 124.674 168.549 1.00 165.82 ? 704 GLN A O   1 
ATOM   5072  C CB  . GLN A 1 684 ? 155.989 124.733 171.656 1.00 166.51 ? 704 GLN A CB  1 
ATOM   5073  C CG  . GLN A 1 684 ? 154.675 125.137 171.012 1.00 162.65 ? 704 GLN A CG  1 
ATOM   5074  C CD  . GLN A 1 684 ? 154.801 126.287 170.044 1.00 160.63 ? 704 GLN A CD  1 
ATOM   5075  O OE1 . GLN A 1 684 ? 155.676 127.148 170.150 1.00 159.80 ? 704 GLN A OE1 1 
ATOM   5076  N NE2 . GLN A 1 684 ? 153.849 126.357 169.130 1.00 158.47 ? 704 GLN A NE2 1 
ATOM   5077  N N   . LEU A 1 685 ? 158.686 125.363 170.177 1.00 167.41 ? 705 LEU A N   1 
ATOM   5078  C CA  . LEU A 1 685 ? 159.455 126.241 169.303 1.00 168.86 ? 705 LEU A CA  1 
ATOM   5079  C C   . LEU A 1 685 ? 160.188 125.419 168.242 1.00 166.84 ? 705 LEU A C   1 
ATOM   5080  O O   . LEU A 1 685 ? 160.304 125.842 167.095 1.00 164.09 ? 705 LEU A O   1 
ATOM   5081  C CB  . LEU A 1 685 ? 160.424 127.083 170.147 1.00 171.88 ? 705 LEU A CB  1 
ATOM   5082  C CG  . LEU A 1 685 ? 161.428 127.943 169.377 1.00 174.82 ? 705 LEU A CG  1 
ATOM   5083  C CD1 . LEU A 1 685 ? 160.742 128.771 168.300 1.00 175.02 ? 705 LEU A CD1 1 
ATOM   5084  C CD2 . LEU A 1 685 ? 162.193 128.847 170.329 1.00 175.73 ? 705 LEU A CD2 1 
ATOM   5085  N N   . GLY A 1 686 ? 160.675 124.236 168.635 1.00 169.50 ? 706 GLY A N   1 
ATOM   5086  C CA  . GLY A 1 686 ? 161.282 123.299 167.705 1.00 172.39 ? 706 GLY A CA  1 
ATOM   5087  C C   . GLY A 1 686 ? 160.323 122.917 166.581 1.00 173.91 ? 706 GLY A C   1 
ATOM   5088  O O   . GLY A 1 686 ? 160.702 122.928 165.414 1.00 172.10 ? 706 GLY A O   1 
ATOM   5089  N N   . ILE A 1 687 ? 159.076 122.593 166.947 1.00 176.99 ? 707 ILE A N   1 
ATOM   5090  C CA  . ILE A 1 687 ? 158.053 122.234 165.978 1.00 178.12 ? 707 ILE A CA  1 
ATOM   5091  C C   . ILE A 1 687 ? 157.803 123.413 165.038 1.00 176.28 ? 707 ILE A C   1 
ATOM   5092  O O   . ILE A 1 687 ? 157.740 123.222 163.830 1.00 174.72 ? 707 ILE A O   1 
ATOM   5093  C CB  . ILE A 1 687 ? 156.767 121.757 166.685 1.00 177.19 ? 707 ILE A CB  1 
ATOM   5094  C CG1 . ILE A 1 687 ? 156.974 120.394 167.354 1.00 178.45 ? 707 ILE A CG1 1 
ATOM   5095  C CG2 . ILE A 1 687 ? 155.588 121.737 165.721 1.00 175.19 ? 707 ILE A CG2 1 
ATOM   5096  C CD1 . ILE A 1 687 ? 155.883 120.001 168.325 1.00 179.40 ? 707 ILE A CD1 1 
ATOM   5097  N N   . ILE A 1 688 ? 157.680 124.623 165.597 1.00 174.42 ? 708 ILE A N   1 
ATOM   5098  C CA  . ILE A 1 688 ? 157.397 125.816 164.812 1.00 175.83 ? 708 ILE A CA  1 
ATOM   5099  C C   . ILE A 1 688 ? 158.505 126.075 163.792 1.00 175.55 ? 708 ILE A C   1 
ATOM   5100  O O   . ILE A 1 688 ? 158.222 126.374 162.632 1.00 174.88 ? 708 ILE A O   1 
ATOM   5101  C CB  . ILE A 1 688 ? 157.192 127.038 165.732 1.00 180.95 ? 708 ILE A CB  1 
ATOM   5102  C CG1 . ILE A 1 688 ? 155.990 126.840 166.656 1.00 184.03 ? 708 ILE A CG1 1 
ATOM   5103  C CG2 . ILE A 1 688 ? 157.065 128.328 164.932 1.00 181.44 ? 708 ILE A CG2 1 
ATOM   5104  C CD1 . ILE A 1 688 ? 154.723 126.494 165.923 1.00 184.85 ? 708 ILE A CD1 1 
ATOM   5105  N N   . VAL A 1 689 ? 159.762 125.996 164.243 1.00 176.10 ? 709 VAL A N   1 
ATOM   5106  C CA  . VAL A 1 689 ? 160.894 126.306 163.380 1.00 174.86 ? 709 VAL A CA  1 
ATOM   5107  C C   . VAL A 1 689 ? 161.039 125.220 162.312 1.00 170.95 ? 709 VAL A C   1 
ATOM   5108  O O   . VAL A 1 689 ? 161.410 125.523 161.177 1.00 166.87 ? 709 VAL A O   1 
ATOM   5109  C CB  . VAL A 1 689 ? 162.202 126.517 164.169 1.00 175.93 ? 709 VAL A CB  1 
ATOM   5110  C CG1 . VAL A 1 689 ? 162.683 125.257 164.871 1.00 176.76 ? 709 VAL A CG1 1 
ATOM   5111  C CG2 . VAL A 1 689 ? 163.301 127.074 163.276 1.00 175.21 ? 709 VAL A CG2 1 
ATOM   5112  N N   . ALA A 1 690 ? 160.734 123.964 162.667 1.00 170.12 ? 710 ALA A N   1 
ATOM   5113  C CA  . ALA A 1 690 ? 160.766 122.869 161.708 1.00 171.24 ? 710 ALA A CA  1 
ATOM   5114  C C   . ALA A 1 690 ? 159.762 123.123 160.583 1.00 171.69 ? 710 ALA A C   1 
ATOM   5115  O O   . ALA A 1 690 ? 160.095 122.961 159.411 1.00 171.80 ? 710 ALA A O   1 
ATOM   5116  C CB  . ALA A 1 690 ? 160.497 121.556 162.404 1.00 172.04 ? 710 ALA A CB  1 
ATOM   5117  N N   . LEU A 1 691 ? 158.538 123.526 160.949 1.00 170.81 ? 711 LEU A N   1 
ATOM   5118  C CA  . LEU A 1 691 ? 157.498 123.836 159.979 1.00 168.84 ? 711 LEU A CA  1 
ATOM   5119  C C   . LEU A 1 691 ? 157.906 125.056 159.157 1.00 164.22 ? 711 LEU A C   1 
ATOM   5120  O O   . LEU A 1 691 ? 157.654 125.095 157.954 1.00 162.02 ? 711 LEU A O   1 
ATOM   5121  C CB  . LEU A 1 691 ? 156.174 124.064 160.723 1.00 170.35 ? 711 LEU A CB  1 
ATOM   5122  C CG  . LEU A 1 691 ? 154.945 124.456 159.894 1.00 172.78 ? 711 LEU A CG  1 
ATOM   5123  C CD1 . LEU A 1 691 ? 154.885 125.960 159.654 1.00 171.20 ? 711 LEU A CD1 1 
ATOM   5124  C CD2 . LEU A 1 691 ? 154.887 123.697 158.571 1.00 175.58 ? 711 LEU A CD2 1 
ATOM   5125  N N   . PHE A 1 692 ? 158.542 126.036 159.811 1.00 162.31 ? 712 PHE A N   1 
ATOM   5126  C CA  . PHE A 1 692 ? 159.034 127.236 159.149 1.00 161.92 ? 712 PHE A CA  1 
ATOM   5127  C C   . PHE A 1 692 ? 160.002 126.855 158.027 1.00 164.56 ? 712 PHE A C   1 
ATOM   5128  O O   . PHE A 1 692 ? 159.918 127.396 156.923 1.00 161.52 ? 712 PHE A O   1 
ATOM   5129  C CB  . PHE A 1 692 ? 159.705 128.149 160.180 1.00 162.63 ? 712 PHE A CB  1 
ATOM   5130  C CG  . PHE A 1 692 ? 160.005 129.560 159.742 1.00 162.48 ? 712 PHE A CG  1 
ATOM   5131  C CD1 . PHE A 1 692 ? 160.946 129.822 158.754 1.00 161.80 ? 712 PHE A CD1 1 
ATOM   5132  C CD2 . PHE A 1 692 ? 159.368 130.633 160.344 1.00 160.03 ? 712 PHE A CD2 1 
ATOM   5133  C CE1 . PHE A 1 692 ? 161.226 131.123 158.368 1.00 159.92 ? 712 PHE A CE1 1 
ATOM   5134  C CE2 . PHE A 1 692 ? 159.656 131.936 159.964 1.00 157.66 ? 712 PHE A CE2 1 
ATOM   5135  C CZ  . PHE A 1 692 ? 160.579 132.176 158.970 1.00 158.25 ? 712 PHE A CZ  1 
ATOM   5136  N N   . ILE A 1 693 ? 160.925 125.933 158.327 1.00 170.56 ? 713 ILE A N   1 
ATOM   5137  C CA  . ILE A 1 693 ? 161.940 125.514 157.370 1.00 174.51 ? 713 ILE A CA  1 
ATOM   5138  C C   . ILE A 1 693 ? 161.297 124.698 156.247 1.00 173.28 ? 713 ILE A C   1 
ATOM   5139  O O   . ILE A 1 693 ? 161.610 124.907 155.077 1.00 170.12 ? 713 ILE A O   1 
ATOM   5140  C CB  . ILE A 1 693 ? 163.081 124.746 158.073 1.00 176.65 ? 713 ILE A CB  1 
ATOM   5141  C CG1 . ILE A 1 693 ? 163.941 125.686 158.925 1.00 176.99 ? 713 ILE A CG1 1 
ATOM   5142  C CG2 . ILE A 1 693 ? 163.924 123.977 157.062 1.00 176.78 ? 713 ILE A CG2 1 
ATOM   5143  C CD1 . ILE A 1 693 ? 165.026 124.996 159.727 1.00 176.91 ? 713 ILE A CD1 1 
ATOM   5144  N N   . MET A 1 694 ? 160.404 123.768 156.609 1.00 173.11 ? 714 MET A N   1 
ATOM   5145  C CA  . MET A 1 694 ? 159.802 122.861 155.642 1.00 173.04 ? 714 MET A CA  1 
ATOM   5146  C C   . MET A 1 694 ? 158.988 123.642 154.609 1.00 174.50 ? 714 MET A C   1 
ATOM   5147  O O   . MET A 1 694 ? 159.128 123.417 153.410 1.00 173.25 ? 714 MET A O   1 
ATOM   5148  C CB  . MET A 1 694 ? 158.902 121.834 156.335 1.00 171.51 ? 714 MET A CB  1 
ATOM   5149  C CG  . MET A 1 694 ? 159.671 120.705 157.000 1.00 170.36 ? 714 MET A CG  1 
ATOM   5150  S SD  . MET A 1 694 ? 158.661 119.231 157.332 1.00 170.99 ? 714 MET A SD  1 
ATOM   5151  C CE  . MET A 1 694 ? 157.076 119.962 157.741 1.00 170.80 ? 714 MET A CE  1 
ATOM   5152  N N   . GLU A 1 695 ? 158.154 124.573 155.080 1.00 175.49 ? 715 GLU A N   1 
ATOM   5153  C CA  . GLU A 1 695 ? 157.354 125.427 154.219 1.00 175.76 ? 715 GLU A CA  1 
ATOM   5154  C C   . GLU A 1 695 ? 157.866 126.859 154.345 1.00 172.75 ? 715 GLU A C   1 
ATOM   5155  O O   . GLU A 1 695 ? 157.596 127.524 155.342 1.00 171.25 ? 715 GLU A O   1 
ATOM   5156  C CB  . GLU A 1 695 ? 155.878 125.339 154.607 1.00 177.40 ? 715 GLU A CB  1 
ATOM   5157  C CG  . GLU A 1 695 ? 155.119 124.200 153.944 1.00 178.74 ? 715 GLU A CG  1 
ATOM   5158  C CD  . GLU A 1 695 ? 155.586 122.801 154.308 1.00 179.53 ? 715 GLU A CD  1 
ATOM   5159  O OE1 . GLU A 1 695 ? 155.777 122.540 155.511 1.00 179.84 ? 715 GLU A OE1 1 
ATOM   5160  O OE2 . GLU A 1 695 ? 155.744 121.974 153.389 1.00 179.67 ? 715 GLU A OE2 1 
ATOM   5161  N N   . PRO A 1 696 ? 158.588 127.391 153.331 1.00 171.74 ? 716 PRO A N   1 
ATOM   5162  C CA  . PRO A 1 696 ? 159.151 128.739 153.402 1.00 171.20 ? 716 PRO A CA  1 
ATOM   5163  C C   . PRO A 1 696 ? 158.066 129.812 153.360 1.00 169.22 ? 716 PRO A C   1 
ATOM   5164  O O   . PRO A 1 696 ? 157.100 129.677 152.613 1.00 168.82 ? 716 PRO A O   1 
ATOM   5165  C CB  . PRO A 1 696 ? 160.041 128.864 152.154 1.00 172.30 ? 716 PRO A CB  1 
ATOM   5166  C CG  . PRO A 1 696 ? 160.140 127.458 151.595 1.00 172.59 ? 716 PRO A CG  1 
ATOM   5167  C CD  . PRO A 1 696 ? 158.885 126.744 152.047 1.00 172.44 ? 716 PRO A CD  1 
ATOM   5168  N N   . PRO A 1 697 ? 158.161 130.873 154.194 1.00 165.46 ? 717 PRO A N   1 
ATOM   5169  C CA  . PRO A 1 697 ? 157.160 131.938 154.189 1.00 161.91 ? 717 PRO A CA  1 
ATOM   5170  C C   . PRO A 1 697 ? 157.408 132.886 153.019 1.00 158.40 ? 717 PRO A C   1 
ATOM   5171  O O   . PRO A 1 697 ? 158.511 133.408 152.865 1.00 156.30 ? 717 PRO A O   1 
ATOM   5172  C CB  . PRO A 1 697 ? 157.341 132.624 155.551 1.00 163.12 ? 717 PRO A CB  1 
ATOM   5173  C CG  . PRO A 1 697 ? 158.780 132.321 155.961 1.00 164.53 ? 717 PRO A CG  1 
ATOM   5174  C CD  . PRO A 1 697 ? 159.220 131.090 155.190 1.00 165.18 ? 717 PRO A CD  1 
ATOM   5175  N N   . ASP A 1 698 ? 156.376 133.088 152.192 1.00 158.10 ? 718 ASP A N   1 
ATOM   5176  C CA  . ASP A 1 698 ? 156.459 133.954 151.026 1.00 158.38 ? 718 ASP A CA  1 
ATOM   5177  C C   . ASP A 1 698 ? 155.108 134.629 150.816 1.00 149.87 ? 718 ASP A C   1 
ATOM   5178  O O   . ASP A 1 698 ? 154.074 134.089 151.202 1.00 147.59 ? 718 ASP A O   1 
ATOM   5179  C CB  . ASP A 1 698 ? 156.883 133.174 149.777 1.00 165.31 ? 718 ASP A CB  1 
ATOM   5180  C CG  . ASP A 1 698 ? 158.358 132.808 149.774 1.00 170.85 ? 718 ASP A CG  1 
ATOM   5181  O OD1 . ASP A 1 698 ? 159.184 133.740 149.814 1.00 172.16 ? 718 ASP A OD1 1 
ATOM   5182  O OD2 . ASP A 1 698 ? 158.669 131.600 149.752 1.00 173.50 ? 718 ASP A OD2 1 
ATOM   5183  N N   . ILE A 1 699 ? 155.123 135.793 150.152 1.00 143.21 ? 719 ILE A N   1 
ATOM   5184  C CA  . ILE A 1 699 ? 153.898 136.502 149.821 1.00 140.28 ? 719 ILE A CA  1 
ATOM   5185  C C   . ILE A 1 699 ? 153.249 135.811 148.623 1.00 139.16 ? 719 ILE A C   1 
ATOM   5186  O O   . ILE A 1 699 ? 153.858 135.699 147.562 1.00 139.45 ? 719 ILE A O   1 
ATOM   5187  C CB  . ILE A 1 699 ? 154.169 138.001 149.570 1.00 138.47 ? 719 ILE A CB  1 
ATOM   5188  C CG1 . ILE A 1 699 ? 154.217 138.792 150.881 1.00 136.94 ? 719 ILE A CG1 1 
ATOM   5189  C CG2 . ILE A 1 699 ? 153.141 138.604 148.621 1.00 138.33 ? 719 ILE A CG2 1 
ATOM   5190  C CD1 . ILE A 1 699 ? 155.333 138.403 151.819 1.00 136.19 ? 719 ILE A CD1 1 
ATOM   5191  N N   . MET A 1 700 ? 152.003 135.362 148.814 1.00 137.22 ? 720 MET A N   1 
ATOM   5192  C CA  . MET A 1 700 ? 151.263 134.640 147.795 1.00 136.01 ? 720 MET A CA  1 
ATOM   5193  C C   . MET A 1 700 ? 150.111 135.518 147.307 1.00 131.75 ? 720 MET A C   1 
ATOM   5194  O O   . MET A 1 700 ? 149.515 136.258 148.091 1.00 129.20 ? 720 MET A O   1 
ATOM   5195  C CB  . MET A 1 700 ? 150.732 133.324 148.382 1.00 137.36 ? 720 MET A CB  1 
ATOM   5196  C CG  . MET A 1 700 ? 149.770 132.533 147.489 1.00 140.03 ? 720 MET A CG  1 
ATOM   5197  S SD  . MET A 1 700 ? 150.617 131.517 146.244 1.00 145.70 ? 720 MET A SD  1 
ATOM   5198  C CE  . MET A 1 700 ? 149.242 131.053 145.193 1.00 146.72 ? 720 MET A CE  1 
ATOM   5199  N N   . HIS A 1 701 ? 149.824 135.433 146.002 1.00 127.38 ? 721 HIS A N   1 
ATOM   5200  C CA  . HIS A 1 701 ? 148.660 136.079 145.420 1.00 123.29 ? 721 HIS A CA  1 
ATOM   5201  C C   . HIS A 1 701 ? 147.559 135.041 145.219 1.00 122.18 ? 721 HIS A C   1 
ATOM   5202  O O   . HIS A 1 701 ? 147.513 134.382 144.186 1.00 123.60 ? 721 HIS A O   1 
ATOM   5203  C CB  . HIS A 1 701 ? 149.028 136.792 144.114 1.00 122.14 ? 721 HIS A CB  1 
ATOM   5204  C CG  . HIS A 1 701 ? 149.712 138.103 144.315 1.00 122.42 ? 721 HIS A CG  1 
ATOM   5205  N ND1 . HIS A 1 701 ? 151.060 138.249 144.565 1.00 124.30 ? 721 HIS A ND1 1 
ATOM   5206  C CD2 . HIS A 1 701 ? 149.210 139.341 144.267 1.00 121.75 ? 721 HIS A CD2 1 
ATOM   5207  C CE1 . HIS A 1 701 ? 151.346 139.538 144.682 1.00 124.03 ? 721 HIS A CE1 1 
ATOM   5208  N NE2 . HIS A 1 701 ? 150.236 140.220 144.504 1.00 122.73 ? 721 HIS A NE2 1 
ATOM   5209  N N   . ASP A 1 702 ? 146.689 134.902 146.226 1.00 121.44 ? 722 ASP A N   1 
ATOM   5210  C CA  . ASP A 1 702 ? 145.571 133.974 146.180 1.00 122.96 ? 722 ASP A CA  1 
ATOM   5211  C C   . ASP A 1 702 ? 144.505 134.531 145.241 1.00 120.42 ? 722 ASP A C   1 
ATOM   5212  O O   . ASP A 1 702 ? 144.274 135.736 145.201 1.00 118.64 ? 722 ASP A O   1 
ATOM   5213  C CB  . ASP A 1 702 ? 145.029 133.718 147.591 1.00 127.30 ? 722 ASP A CB  1 
ATOM   5214  C CG  . ASP A 1 702 ? 143.789 132.839 147.685 1.00 130.91 ? 722 ASP A CG  1 
ATOM   5215  O OD1 . ASP A 1 702 ? 142.988 132.821 146.737 1.00 130.86 ? 722 ASP A OD1 1 
ATOM   5216  O OD2 . ASP A 1 702 ? 143.643 132.158 148.716 1.00 133.57 ? 722 ASP A OD2 1 
ATOM   5217  N N   . TYR A 1 703 ? 143.842 133.622 144.514 1.00 118.66 ? 723 TYR A N   1 
ATOM   5218  C CA  . TYR A 1 703 ? 142.779 133.975 143.585 1.00 116.29 ? 723 TYR A CA  1 
ATOM   5219  C C   . TYR A 1 703 ? 141.531 133.163 143.934 1.00 116.32 ? 723 TYR A C   1 
ATOM   5220  O O   . TYR A 1 703 ? 141.288 132.110 143.346 1.00 115.34 ? 723 TYR A O   1 
ATOM   5221  C CB  . TYR A 1 703 ? 143.210 133.718 142.139 1.00 114.86 ? 723 TYR A CB  1 
ATOM   5222  C CG  . TYR A 1 703 ? 144.554 134.284 141.758 1.00 113.36 ? 723 TYR A CG  1 
ATOM   5223  C CD1 . TYR A 1 703 ? 144.807 135.644 141.826 1.00 112.22 ? 723 TYR A CD1 1 
ATOM   5224  C CD2 . TYR A 1 703 ? 145.580 133.456 141.327 1.00 114.11 ? 723 TYR A CD2 1 
ATOM   5225  C CE1 . TYR A 1 703 ? 146.044 136.165 141.480 1.00 113.24 ? 723 TYR A CE1 1 
ATOM   5226  C CE2 . TYR A 1 703 ? 146.822 133.962 140.978 1.00 114.45 ? 723 TYR A CE2 1 
ATOM   5227  C CZ  . TYR A 1 703 ? 147.058 135.322 141.062 1.00 114.19 ? 723 TYR A CZ  1 
ATOM   5228  O OH  . TYR A 1 703 ? 148.285 135.837 140.720 1.00 114.51 ? 723 TYR A OH  1 
ATOM   5229  N N   . PRO A 1 704 ? 140.703 133.615 144.905 1.00 118.83 ? 724 PRO A N   1 
ATOM   5230  C CA  . PRO A 1 704 ? 139.567 132.823 145.377 1.00 120.04 ? 724 PRO A CA  1 
ATOM   5231  C C   . PRO A 1 704 ? 138.489 132.681 144.307 1.00 118.62 ? 724 PRO A C   1 
ATOM   5232  O O   . PRO A 1 704 ? 137.976 131.585 144.091 1.00 118.70 ? 724 PRO A O   1 
ATOM   5233  C CB  . PRO A 1 704 ? 139.032 133.598 146.596 1.00 121.59 ? 724 PRO A CB  1 
ATOM   5234  C CG  . PRO A 1 704 ? 140.109 134.626 146.916 1.00 122.29 ? 724 PRO A CG  1 
ATOM   5235  C CD  . PRO A 1 704 ? 140.810 134.902 145.604 1.00 120.64 ? 724 PRO A CD  1 
ATOM   5236  N N   . SER A 1 705 ? 138.165 133.800 143.642 1.00 117.24 ? 725 SER A N   1 
ATOM   5237  C CA  . SER A 1 705 ? 137.206 133.800 142.548 1.00 116.33 ? 725 SER A CA  1 
ATOM   5238  C C   . SER A 1 705 ? 137.836 134.435 141.310 1.00 114.55 ? 725 SER A C   1 
ATOM   5239  O O   . SER A 1 705 ? 138.996 134.840 141.346 1.00 115.84 ? 725 SER A O   1 
ATOM   5240  C CB  . SER A 1 705 ? 135.934 134.495 142.957 1.00 116.53 ? 725 SER A CB  1 
ATOM   5241  O OG  . SER A 1 705 ? 136.145 135.887 143.131 1.00 116.94 ? 725 SER A OG  1 
ATOM   5242  N N   . ILE A 1 706 ? 137.063 134.516 140.221 1.00 111.81 ? 726 ILE A N   1 
ATOM   5243  C CA  . ILE A 1 706 ? 137.596 134.981 138.953 1.00 110.50 ? 726 ILE A CA  1 
ATOM   5244  C C   . ILE A 1 706 ? 137.752 136.500 138.963 1.00 108.14 ? 726 ILE A C   1 
ATOM   5245  O O   . ILE A 1 706 ? 138.496 137.033 138.146 1.00 108.35 ? 726 ILE A O   1 
ATOM   5246  C CB  . ILE A 1 706 ? 136.718 134.516 137.772 1.00 111.95 ? 726 ILE A CB  1 
ATOM   5247  C CG1 . ILE A 1 706 ? 137.542 134.394 136.487 1.00 112.71 ? 726 ILE A CG1 1 
ATOM   5248  C CG2 . ILE A 1 706 ? 135.497 135.410 137.585 1.00 112.02 ? 726 ILE A CG2 1 
ATOM   5249  C CD1 . ILE A 1 706 ? 138.478 133.202 136.473 1.00 113.70 ? 726 ILE A CD1 1 
ATOM   5250  N N   . ARG A 1 707 ? 137.049 137.190 139.872 1.00 106.58 ? 727 ARG A N   1 
ATOM   5251  C CA  . ARG A 1 707 ? 137.026 138.645 139.875 1.00 107.58 ? 727 ARG A CA  1 
ATOM   5252  C C   . ARG A 1 707 ? 138.090 139.204 140.816 1.00 109.20 ? 727 ARG A C   1 
ATOM   5253  O O   . ARG A 1 707 ? 138.967 139.945 140.382 1.00 109.48 ? 727 ARG A O   1 
ATOM   5254  C CB  . ARG A 1 707 ? 135.636 139.153 140.266 1.00 108.47 ? 727 ARG A CB  1 
ATOM   5255  C CG  . ARG A 1 707 ? 134.630 139.102 139.127 1.00 111.31 ? 727 ARG A CG  1 
ATOM   5256  C CD  . ARG A 1 707 ? 133.227 139.484 139.561 1.00 114.19 ? 727 ARG A CD  1 
ATOM   5257  N NE  . ARG A 1 707 ? 132.338 139.756 138.436 1.00 116.48 ? 727 ARG A NE  1 
ATOM   5258  C CZ  . ARG A 1 707 ? 132.006 138.877 137.493 1.00 117.41 ? 727 ARG A CZ  1 
ATOM   5259  N NH1 . ARG A 1 707 ? 132.456 137.635 137.548 1.00 117.47 ? 727 ARG A NH1 1 
ATOM   5260  N NH2 . ARG A 1 707 ? 131.208 139.239 136.502 1.00 116.94 ? 727 ARG A NH2 1 
ATOM   5261  N N   . GLU A 1 708 ? 138.005 138.847 142.103 1.00 111.35 ? 728 GLU A N   1 
ATOM   5262  C CA  . GLU A 1 708 ? 138.785 139.519 143.134 1.00 112.02 ? 728 GLU A CA  1 
ATOM   5263  C C   . GLU A 1 708 ? 140.088 138.764 143.389 1.00 110.01 ? 728 GLU A C   1 
ATOM   5264  O O   . GLU A 1 708 ? 140.137 137.540 143.271 1.00 108.97 ? 728 GLU A O   1 
ATOM   5265  C CB  . GLU A 1 708 ? 137.967 139.708 144.417 1.00 113.74 ? 728 GLU A CB  1 
ATOM   5266  C CG  . GLU A 1 708 ? 137.232 138.472 144.915 1.00 115.31 ? 728 GLU A CG  1 
ATOM   5267  C CD  . GLU A 1 708 ? 138.071 137.354 145.511 1.00 116.63 ? 728 GLU A CD  1 
ATOM   5268  O OE1 . GLU A 1 708 ? 139.208 137.615 145.932 1.00 115.25 ? 728 GLU A OE1 1 
ATOM   5269  O OE2 . GLU A 1 708 ? 137.579 136.219 145.556 1.00 117.40 ? 728 GLU A OE2 1 
ATOM   5270  N N   . VAL A 1 709 ? 141.130 139.527 143.744 1.00 109.62 ? 729 VAL A N   1 
ATOM   5271  C CA  . VAL A 1 709 ? 142.439 138.979 144.049 1.00 110.07 ? 729 VAL A CA  1 
ATOM   5272  C C   . VAL A 1 709 ? 142.882 139.496 145.416 1.00 112.77 ? 729 VAL A C   1 
ATOM   5273  O O   . VAL A 1 709 ? 142.711 140.677 145.710 1.00 115.19 ? 729 VAL A O   1 
ATOM   5274  C CB  . VAL A 1 709 ? 143.456 139.358 142.958 1.00 109.67 ? 729 VAL A CB  1 
ATOM   5275  C CG1 . VAL A 1 709 ? 143.485 140.859 142.698 1.00 110.35 ? 729 VAL A CG1 1 
ATOM   5276  C CG2 . VAL A 1 709 ? 144.852 138.869 143.294 1.00 109.87 ? 729 VAL A CG2 1 
ATOM   5277  N N   . TYR A 1 710 ? 143.444 138.595 146.229 1.00 113.32 ? 730 TYR A N   1 
ATOM   5278  C CA  . TYR A 1 710 ? 144.015 138.966 147.509 1.00 113.66 ? 730 TYR A CA  1 
ATOM   5279  C C   . TYR A 1 710 ? 145.456 138.483 147.594 1.00 113.89 ? 730 TYR A C   1 
ATOM   5280  O O   . TYR A 1 710 ? 145.847 137.567 146.872 1.00 115.21 ? 730 TYR A O   1 
ATOM   5281  C CB  . TYR A 1 710 ? 143.199 138.367 148.652 1.00 114.98 ? 730 TYR A CB  1 
ATOM   5282  C CG  . TYR A 1 710 ? 141.746 138.765 148.668 1.00 116.00 ? 730 TYR A CG  1 
ATOM   5283  C CD1 . TYR A 1 710 ? 141.354 140.085 148.512 1.00 116.68 ? 730 TYR A CD1 1 
ATOM   5284  C CD2 . TYR A 1 710 ? 140.759 137.817 148.880 1.00 117.02 ? 730 TYR A CD2 1 
ATOM   5285  C CE1 . TYR A 1 710 ? 140.018 140.448 148.557 1.00 118.85 ? 730 TYR A CE1 1 
ATOM   5286  C CE2 . TYR A 1 710 ? 139.419 138.165 148.935 1.00 118.21 ? 730 TYR A CE2 1 
ATOM   5287  C CZ  . TYR A 1 710 ? 139.045 139.487 148.765 1.00 119.85 ? 730 TYR A CZ  1 
ATOM   5288  O OH  . TYR A 1 710 ? 137.724 139.870 148.807 1.00 120.89 ? 730 TYR A OH  1 
ATOM   5289  N N   . LEU A 1 711 ? 146.227 139.126 148.479 1.00 112.84 ? 731 LEU A N   1 
ATOM   5290  C CA  . LEU A 1 711 ? 147.558 138.651 148.813 1.00 112.27 ? 731 LEU A CA  1 
ATOM   5291  C C   . LEU A 1 711 ? 147.587 138.254 150.287 1.00 112.85 ? 731 LEU A C   1 
ATOM   5292  O O   . LEU A 1 711 ? 147.207 139.023 151.167 1.00 111.28 ? 731 LEU A O   1 
ATOM   5293  C CB  . LEU A 1 711 ? 148.630 139.695 148.464 1.00 111.03 ? 731 LEU A CB  1 
ATOM   5294  C CG  . LEU A 1 711 ? 148.778 140.916 149.376 1.00 109.34 ? 731 LEU A CG  1 
ATOM   5295  C CD1 . LEU A 1 711 ? 150.233 141.365 149.437 1.00 109.10 ? 731 LEU A CD1 1 
ATOM   5296  C CD2 . LEU A 1 711 ? 147.913 142.075 148.904 1.00 109.31 ? 731 LEU A CD2 1 
ATOM   5297  N N   . ILE A 1 712 ? 148.022 137.016 150.523 1.00 116.54 ? 732 ILE A N   1 
ATOM   5298  C CA  . ILE A 1 712 ? 148.196 136.459 151.852 1.00 121.18 ? 732 ILE A CA  1 
ATOM   5299  C C   . ILE A 1 712 ? 149.512 135.689 151.841 1.00 127.50 ? 732 ILE A C   1 
ATOM   5300  O O   . ILE A 1 712 ? 150.036 135.397 150.769 1.00 132.40 ? 732 ILE A O   1 
ATOM   5301  C CB  . ILE A 1 712 ? 147.001 135.558 152.216 1.00 122.48 ? 732 ILE A CB  1 
ATOM   5302  C CG1 . ILE A 1 712 ? 146.671 134.579 151.085 1.00 122.10 ? 732 ILE A CG1 1 
ATOM   5303  C CG2 . ILE A 1 712 ? 145.794 136.400 152.604 1.00 124.75 ? 732 ILE A CG2 1 
ATOM   5304  C CD1 . ILE A 1 712 ? 145.795 133.424 151.503 1.00 123.87 ? 732 ILE A CD1 1 
ATOM   5305  N N   . CYS A 1 713 ? 150.041 135.374 153.028 1.00 131.12 ? 733 CYS A N   1 
ATOM   5306  C CA  . CYS A 1 713 ? 151.342 134.734 153.110 1.00 134.97 ? 733 CYS A CA  1 
ATOM   5307  C C   . CYS A 1 713 ? 151.167 133.219 153.150 1.00 131.39 ? 733 CYS A C   1 
ATOM   5308  O O   . CYS A 1 713 ? 150.297 132.716 153.860 1.00 127.87 ? 733 CYS A O   1 
ATOM   5309  C CB  . CYS A 1 713 ? 152.130 135.223 154.316 1.00 142.03 ? 733 CYS A CB  1 
ATOM   5310  S SG  . CYS A 1 713 ? 153.876 135.476 153.918 1.00 151.45 ? 733 CYS A SG  1 
ATOM   5311  N N   . ASN A 1 714 ? 152.009 132.509 152.390 1.00 132.94 ? 734 ASN A N   1 
ATOM   5312  C CA  . ASN A 1 714 ? 151.770 131.106 152.086 1.00 136.22 ? 734 ASN A CA  1 
ATOM   5313  C C   . ASN A 1 714 ? 151.873 130.277 153.365 1.00 135.24 ? 734 ASN A C   1 
ATOM   5314  O O   . ASN A 1 714 ? 152.966 130.045 153.874 1.00 135.06 ? 734 ASN A O   1 
ATOM   5315  C CB  . ASN A 1 714 ? 152.724 130.609 150.997 1.00 138.09 ? 734 ASN A CB  1 
ATOM   5316  C CG  . ASN A 1 714 ? 154.161 130.541 151.465 1.00 139.08 ? 734 ASN A CG  1 
ATOM   5317  O OD1 . ASN A 1 714 ? 154.719 131.537 151.919 1.00 138.89 ? 734 ASN A OD1 1 
ATOM   5318  N ND2 . ASN A 1 714 ? 154.757 129.364 151.398 1.00 140.61 ? 734 ASN A ND2 1 
ATOM   5319  N N   . THR A 1 715 ? 150.715 129.865 153.893 1.00 135.30 ? 735 THR A N   1 
ATOM   5320  C CA  . THR A 1 715 ? 150.659 129.033 155.081 1.00 136.16 ? 735 THR A CA  1 
ATOM   5321  C C   . THR A 1 715 ? 149.759 127.840 154.779 1.00 138.68 ? 735 THR A C   1 
ATOM   5322  O O   . THR A 1 715 ? 148.541 127.984 154.677 1.00 138.57 ? 735 THR A O   1 
ATOM   5323  C CB  . THR A 1 715 ? 150.170 129.828 156.300 1.00 136.38 ? 735 THR A CB  1 
ATOM   5324  O OG1 . THR A 1 715 ? 150.860 131.079 156.336 1.00 134.38 ? 735 THR A OG1 1 
ATOM   5325  C CG2 . THR A 1 715 ? 150.380 129.090 157.605 1.00 137.48 ? 735 THR A CG2 1 
ATOM   5326  N N   . THR A 1 716 ? 150.371 126.660 154.643 1.00 143.50 ? 736 THR A N   1 
ATOM   5327  C CA  . THR A 1 716 ? 149.639 125.466 154.253 1.00 148.20 ? 736 THR A CA  1 
ATOM   5328  C C   . THR A 1 716 ? 148.716 125.054 155.397 1.00 150.91 ? 736 THR A C   1 
ATOM   5329  O O   . THR A 1 716 ? 148.851 125.541 156.517 1.00 150.07 ? 736 THR A O   1 
ATOM   5330  C CB  . THR A 1 716 ? 150.579 124.319 153.856 1.00 151.08 ? 736 THR A CB  1 
ATOM   5331  O OG1 . THR A 1 716 ? 151.103 123.737 155.050 1.00 150.21 ? 736 THR A OG1 1 
ATOM   5332  C CG2 . THR A 1 716 ? 151.700 124.754 152.936 1.00 152.41 ? 736 THR A CG2 1 
ATOM   5333  N N   . ASN A 1 717 ? 147.780 124.149 155.097 1.00 155.77 ? 737 ASN A N   1 
ATOM   5334  C CA  . ASN A 1 717 ? 146.863 123.607 156.088 1.00 159.85 ? 737 ASN A CA  1 
ATOM   5335  C C   . ASN A 1 717 ? 147.646 123.014 157.258 1.00 159.97 ? 737 ASN A C   1 
ATOM   5336  O O   . ASN A 1 717 ? 147.308 123.271 158.413 1.00 157.79 ? 737 ASN A O   1 
ATOM   5337  C CB  . ASN A 1 717 ? 145.908 122.572 155.484 1.00 164.42 ? 737 ASN A CB  1 
ATOM   5338  C CG  . ASN A 1 717 ? 146.551 121.726 154.404 1.00 168.60 ? 737 ASN A CG  1 
ATOM   5339  O OD1 . ASN A 1 717 ? 147.756 121.481 154.427 1.00 168.95 ? 737 ASN A OD1 1 
ATOM   5340  N ND2 . ASN A 1 717 ? 145.767 121.332 153.415 1.00 169.87 ? 737 ASN A ND2 1 
ATOM   5341  N N   . LEU A 1 718 ? 148.686 122.223 156.957 1.00 162.26 ? 738 LEU A N   1 
ATOM   5342  C CA  . LEU A 1 718 ? 149.519 121.646 158.003 1.00 165.21 ? 738 LEU A CA  1 
ATOM   5343  C C   . LEU A 1 718 ? 150.230 122.767 158.760 1.00 158.25 ? 738 LEU A C   1 
ATOM   5344  O O   . LEU A 1 718 ? 150.328 122.726 159.989 1.00 156.29 ? 738 LEU A O   1 
ATOM   5345  C CB  . LEU A 1 718 ? 150.529 120.653 157.407 1.00 171.49 ? 738 LEU A CB  1 
ATOM   5346  C CG  . LEU A 1 718 ? 149.980 119.282 157.003 1.00 174.61 ? 738 LEU A CG  1 
ATOM   5347  C CD1 . LEU A 1 718 ? 149.747 119.199 155.501 1.00 175.07 ? 738 LEU A CD1 1 
ATOM   5348  C CD2 . LEU A 1 718 ? 150.909 118.158 157.452 1.00 175.05 ? 738 LEU A CD2 1 
ATOM   5349  N N   . GLY A 1 719 ? 150.686 123.781 158.009 1.00 152.87 ? 739 GLY A N   1 
ATOM   5350  C CA  . GLY A 1 719 ? 151.439 124.893 158.565 1.00 151.68 ? 739 GLY A CA  1 
ATOM   5351  C C   . GLY A 1 719 ? 150.659 125.683 159.612 1.00 151.84 ? 739 GLY A C   1 
ATOM   5352  O O   . GLY A 1 719 ? 151.266 126.302 160.480 1.00 151.35 ? 739 GLY A O   1 
ATOM   5353  N N   . VAL A 1 720 ? 149.322 125.662 159.526 1.00 150.81 ? 740 VAL A N   1 
ATOM   5354  C CA  . VAL A 1 720 ? 148.492 126.344 160.506 1.00 148.77 ? 740 VAL A CA  1 
ATOM   5355  C C   . VAL A 1 720 ? 148.050 125.364 161.593 1.00 146.42 ? 740 VAL A C   1 
ATOM   5356  O O   . VAL A 1 720 ? 148.029 125.731 162.768 1.00 143.20 ? 740 VAL A O   1 
ATOM   5357  C CB  . VAL A 1 720 ? 147.294 127.069 159.854 1.00 151.68 ? 740 VAL A CB  1 
ATOM   5358  C CG1 . VAL A 1 720 ? 146.480 126.175 158.930 1.00 154.36 ? 740 VAL A CG1 1 
ATOM   5359  C CG2 . VAL A 1 720 ? 146.390 127.714 160.895 1.00 151.90 ? 740 VAL A CG2 1 
ATOM   5360  N N   . VAL A 1 721 ? 147.704 124.126 161.212 1.00 149.56 ? 741 VAL A N   1 
ATOM   5361  C CA  . VAL A 1 721 ? 147.036 123.215 162.135 1.00 153.40 ? 741 VAL A CA  1 
ATOM   5362  C C   . VAL A 1 721 ? 148.032 122.590 163.111 1.00 152.86 ? 741 VAL A C   1 
ATOM   5363  O O   . VAL A 1 721 ? 147.618 122.093 164.154 1.00 153.33 ? 741 VAL A O   1 
ATOM   5364  C CB  . VAL A 1 721 ? 146.227 122.098 161.438 1.00 156.41 ? 741 VAL A CB  1 
ATOM   5365  C CG1 . VAL A 1 721 ? 145.110 122.630 160.548 1.00 157.42 ? 741 VAL A CG1 1 
ATOM   5366  C CG2 . VAL A 1 721 ? 147.119 121.118 160.686 1.00 156.31 ? 741 VAL A CG2 1 
ATOM   5367  N N   . ALA A 1 722 ? 149.330 122.586 162.776 1.00 150.45 ? 742 ALA A N   1 
ATOM   5368  C CA  . ALA A 1 722 ? 150.338 122.014 163.658 1.00 148.87 ? 742 ALA A CA  1 
ATOM   5369  C C   . ALA A 1 722 ? 150.449 122.809 164.964 1.00 144.84 ? 742 ALA A C   1 
ATOM   5370  O O   . ALA A 1 722 ? 150.278 122.225 166.034 1.00 144.42 ? 742 ALA A O   1 
ATOM   5371  C CB  . ALA A 1 722 ? 151.663 121.895 162.940 1.00 149.62 ? 742 ALA A CB  1 
ATOM   5372  N N   . PRO A 1 723 ? 150.714 124.141 164.947 1.00 141.65 ? 743 PRO A N   1 
ATOM   5373  C CA  . PRO A 1 723 ? 150.730 124.923 166.184 1.00 141.31 ? 743 PRO A CA  1 
ATOM   5374  C C   . PRO A 1 723 ? 149.402 124.833 166.935 1.00 140.63 ? 743 PRO A C   1 
ATOM   5375  O O   . PRO A 1 723 ? 149.394 124.705 168.158 1.00 137.67 ? 743 PRO A O   1 
ATOM   5376  C CB  . PRO A 1 723 ? 150.994 126.370 165.734 1.00 140.77 ? 743 PRO A CB  1 
ATOM   5377  C CG  . PRO A 1 723 ? 151.612 126.233 164.356 1.00 140.52 ? 743 PRO A CG  1 
ATOM   5378  C CD  . PRO A 1 723 ? 151.013 124.971 163.769 1.00 140.55 ? 743 PRO A CD  1 
ATOM   5379  N N   . LEU A 1 724 ? 148.293 124.899 166.185 1.00 143.12 ? 744 LEU A N   1 
ATOM   5380  C CA  . LEU A 1 724 ? 146.963 124.810 166.765 1.00 146.28 ? 744 LEU A CA  1 
ATOM   5381  C C   . LEU A 1 724 ? 146.790 123.449 167.431 1.00 148.80 ? 744 LEU A C   1 
ATOM   5382  O O   . LEU A 1 724 ? 146.236 123.370 168.525 1.00 147.13 ? 744 LEU A O   1 
ATOM   5383  C CB  . LEU A 1 724 ? 145.906 125.016 165.674 1.00 147.81 ? 744 LEU A CB  1 
ATOM   5384  C CG  . LEU A 1 724 ? 145.947 126.352 164.934 1.00 148.69 ? 744 LEU A CG  1 
ATOM   5385  C CD1 . LEU A 1 724 ? 144.689 126.536 164.098 1.00 149.96 ? 744 LEU A CD1 1 
ATOM   5386  C CD2 . LEU A 1 724 ? 146.129 127.517 165.894 1.00 148.46 ? 744 LEU A CD2 1 
ATOM   5387  N N   . GLY A 1 725 ? 147.266 122.390 166.761 1.00 153.87 ? 745 GLY A N   1 
ATOM   5388  C CA  . GLY A 1 725 ? 147.177 121.040 167.293 1.00 158.00 ? 745 GLY A CA  1 
ATOM   5389  C C   . GLY A 1 725 ? 147.890 120.917 168.638 1.00 160.55 ? 745 GLY A C   1 
ATOM   5390  O O   . GLY A 1 725 ? 147.332 120.395 169.607 1.00 160.98 ? 745 GLY A O   1 
ATOM   5391  N N   . TYR A 1 726 ? 149.129 121.421 168.678 1.00 162.34 ? 746 TYR A N   1 
ATOM   5392  C CA  . TYR A 1 726 ? 149.944 121.339 169.877 1.00 162.82 ? 746 TYR A CA  1 
ATOM   5393  C C   . TYR A 1 726 ? 149.272 122.119 171.004 1.00 154.67 ? 746 TYR A C   1 
ATOM   5394  O O   . TYR A 1 726 ? 149.119 121.610 172.114 1.00 153.24 ? 746 TYR A O   1 
ATOM   5395  C CB  . TYR A 1 726 ? 151.364 121.839 169.597 1.00 168.09 ? 746 TYR A CB  1 
ATOM   5396  C CG  . TYR A 1 726 ? 152.282 121.782 170.789 1.00 172.23 ? 746 TYR A CG  1 
ATOM   5397  C CD1 . TYR A 1 726 ? 152.235 122.746 171.784 1.00 173.05 ? 746 TYR A CD1 1 
ATOM   5398  C CD2 . TYR A 1 726 ? 153.190 120.745 170.931 1.00 175.87 ? 746 TYR A CD2 1 
ATOM   5399  C CE1 . TYR A 1 726 ? 153.076 122.689 172.884 1.00 174.67 ? 746 TYR A CE1 1 
ATOM   5400  C CE2 . TYR A 1 726 ? 154.034 120.670 172.025 1.00 176.77 ? 746 TYR A CE2 1 
ATOM   5401  C CZ  . TYR A 1 726 ? 153.976 121.644 173.005 1.00 176.54 ? 746 TYR A CZ  1 
ATOM   5402  O OH  . TYR A 1 726 ? 154.811 121.557 174.087 1.00 177.94 ? 746 TYR A OH  1 
ATOM   5403  N N   . ASN A 1 727 ? 148.847 123.348 170.696 1.00 146.18 ? 747 ASN A N   1 
ATOM   5404  C CA  . ASN A 1 727 ? 148.240 124.204 171.698 1.00 141.48 ? 747 ASN A CA  1 
ATOM   5405  C C   . ASN A 1 727 ? 146.944 123.574 172.198 1.00 140.33 ? 747 ASN A C   1 
ATOM   5406  O O   . ASN A 1 727 ? 146.612 123.714 173.369 1.00 139.23 ? 747 ASN A O   1 
ATOM   5407  C CB  . ASN A 1 727 ? 148.023 125.621 171.172 1.00 139.67 ? 747 ASN A CB  1 
ATOM   5408  C CG  . ASN A 1 727 ? 149.322 126.302 170.793 1.00 138.96 ? 747 ASN A CG  1 
ATOM   5409  O OD1 . ASN A 1 727 ? 150.366 126.026 171.379 1.00 139.22 ? 747 ASN A OD1 1 
ATOM   5410  N ND2 . ASN A 1 727 ? 149.274 127.177 169.802 1.00 137.84 ? 747 ASN A ND2 1 
ATOM   5411  N N   . GLY A 1 728 ? 146.225 122.881 171.309 1.00 141.23 ? 748 GLY A N   1 
ATOM   5412  C CA  . GLY A 1 728 ? 145.004 122.183 171.678 1.00 142.13 ? 748 GLY A CA  1 
ATOM   5413  C C   . GLY A 1 728 ? 145.267 121.074 172.691 1.00 141.53 ? 748 GLY A C   1 
ATOM   5414  O O   . GLY A 1 728 ? 144.527 120.933 173.663 1.00 140.84 ? 748 GLY A O   1 
ATOM   5415  N N   . LEU A 1 729 ? 146.327 120.293 172.454 1.00 142.93 ? 749 LEU A N   1 
ATOM   5416  C CA  . LEU A 1 729 ? 146.739 119.272 173.404 1.00 145.09 ? 749 LEU A CA  1 
ATOM   5417  C C   . LEU A 1 729 ? 147.071 119.929 174.744 1.00 142.51 ? 749 LEU A C   1 
ATOM   5418  O O   . LEU A 1 729 ? 146.716 119.406 175.798 1.00 141.10 ? 749 LEU A O   1 
ATOM   5419  C CB  . LEU A 1 729 ? 147.940 118.499 172.846 1.00 147.53 ? 749 LEU A CB  1 
ATOM   5420  C CG  . LEU A 1 729 ? 147.670 117.610 171.630 1.00 149.41 ? 749 LEU A CG  1 
ATOM   5421  C CD1 . LEU A 1 729 ? 148.935 116.877 171.209 1.00 150.30 ? 749 LEU A CD1 1 
ATOM   5422  C CD2 . LEU A 1 729 ? 146.552 116.610 171.900 1.00 149.23 ? 749 LEU A CD2 1 
ATOM   5423  N N   . LEU A 1 730 ? 147.729 121.092 174.688 1.00 141.17 ? 750 LEU A N   1 
ATOM   5424  C CA  . LEU A 1 730 ? 148.119 121.813 175.889 1.00 140.76 ? 750 LEU A CA  1 
ATOM   5425  C C   . LEU A 1 730 ? 146.885 122.257 176.675 1.00 141.69 ? 750 LEU A C   1 
ATOM   5426  O O   . LEU A 1 730 ? 146.839 122.087 177.892 1.00 139.50 ? 750 LEU A O   1 
ATOM   5427  C CB  . LEU A 1 730 ? 148.999 122.999 175.483 1.00 137.97 ? 750 LEU A CB  1 
ATOM   5428  C CG  . LEU A 1 730 ? 149.506 123.896 176.611 1.00 135.68 ? 750 LEU A CG  1 
ATOM   5429  C CD1 . LEU A 1 730 ? 150.102 123.084 177.751 1.00 135.24 ? 750 LEU A CD1 1 
ATOM   5430  C CD2 . LEU A 1 730 ? 150.540 124.868 176.068 1.00 134.67 ? 750 LEU A CD2 1 
ATOM   5431  N N   . ILE A 1 731 ? 145.877 122.796 175.978 1.00 144.23 ? 751 ILE A N   1 
ATOM   5432  C CA  . ILE A 1 731 ? 144.690 123.305 176.653 1.00 147.11 ? 751 ILE A CA  1 
ATOM   5433  C C   . ILE A 1 731 ? 143.880 122.134 177.206 1.00 153.60 ? 751 ILE A C   1 
ATOM   5434  O O   . ILE A 1 731 ? 143.260 122.264 178.258 1.00 153.51 ? 751 ILE A O   1 
ATOM   5435  C CB  . ILE A 1 731 ? 143.815 124.196 175.748 1.00 146.45 ? 751 ILE A CB  1 
ATOM   5436  C CG1 . ILE A 1 731 ? 144.623 125.243 174.980 1.00 145.97 ? 751 ILE A CG1 1 
ATOM   5437  C CG2 . ILE A 1 731 ? 142.711 124.859 176.565 1.00 145.77 ? 751 ILE A CG2 1 
ATOM   5438  C CD1 . ILE A 1 731 ? 143.960 125.682 173.696 1.00 145.26 ? 751 ILE A CD1 1 
ATOM   5439  N N   . LEU A 1 732 ? 143.901 120.988 176.513 1.00 163.00 ? 752 LEU A N   1 
ATOM   5440  C CA  . LEU A 1 732 ? 143.164 119.826 176.975 1.00 172.94 ? 752 LEU A CA  1 
ATOM   5441  C C   . LEU A 1 732 ? 143.789 119.317 178.272 1.00 175.26 ? 752 LEU A C   1 
ATOM   5442  O O   . LEU A 1 732 ? 143.074 118.975 179.208 1.00 177.09 ? 752 LEU A O   1 
ATOM   5443  C CB  . LEU A 1 732 ? 143.146 118.749 175.882 1.00 179.14 ? 752 LEU A CB  1 
ATOM   5444  C CG  . LEU A 1 732 ? 142.269 117.526 176.164 1.00 185.09 ? 752 LEU A CG  1 
ATOM   5445  C CD1 . LEU A 1 732 ? 140.793 117.900 176.204 1.00 187.14 ? 752 LEU A CD1 1 
ATOM   5446  C CD2 . LEU A 1 732 ? 142.512 116.437 175.130 1.00 185.98 ? 752 LEU A CD2 1 
ATOM   5447  N N   . ALA A 1 733 ? 145.125 119.282 178.335 1.00 174.31 ? 753 ALA A N   1 
ATOM   5448  C CA  . ALA A 1 733 ? 145.813 118.909 179.560 1.00 173.32 ? 753 ALA A CA  1 
ATOM   5449  C C   . ALA A 1 733 ? 145.485 119.912 180.666 1.00 168.19 ? 753 ALA A C   1 
ATOM   5450  O O   . ALA A 1 733 ? 145.259 119.520 181.808 1.00 170.79 ? 753 ALA A O   1 
ATOM   5451  C CB  . ALA A 1 733 ? 147.300 118.821 179.311 1.00 174.40 ? 753 ALA A CB  1 
ATOM   5452  N N   . CYS A 1 734 ? 145.437 121.199 180.300 1.00 160.44 ? 754 CYS A N   1 
ATOM   5453  C CA  . CYS A 1 734 ? 145.226 122.257 181.272 1.00 157.59 ? 754 CYS A CA  1 
ATOM   5454  C C   . CYS A 1 734 ? 143.824 122.155 181.869 1.00 160.89 ? 754 CYS A C   1 
ATOM   5455  O O   . CYS A 1 734 ? 143.649 122.354 183.070 1.00 161.10 ? 754 CYS A O   1 
ATOM   5456  C CB  . CYS A 1 734 ? 145.426 123.633 180.647 1.00 154.35 ? 754 CYS A CB  1 
ATOM   5457  S SG  . CYS A 1 734 ? 145.704 124.954 181.858 1.00 147.25 ? 754 CYS A SG  1 
ATOM   5458  N N   . THR A 1 735 ? 142.824 121.874 181.022 1.00 165.30 ? 755 THR A N   1 
ATOM   5459  C CA  . THR A 1 735 ? 141.458 121.748 181.501 1.00 169.47 ? 755 THR A CA  1 
ATOM   5460  C C   . THR A 1 735 ? 141.331 120.499 182.372 1.00 173.26 ? 755 THR A C   1 
ATOM   5461  O O   . THR A 1 735 ? 140.623 120.543 183.364 1.00 170.77 ? 755 THR A O   1 
ATOM   5462  C CB  . THR A 1 735 ? 140.422 121.798 180.367 1.00 170.19 ? 755 THR A CB  1 
ATOM   5463  O OG1 . THR A 1 735 ? 139.126 121.724 180.963 1.00 170.88 ? 755 THR A OG1 1 
ATOM   5464  C CG2 . THR A 1 735 ? 140.577 120.696 179.344 1.00 169.19 ? 755 THR A CG2 1 
ATOM   5465  N N   . PHE A 1 736 ? 142.039 119.417 182.023 1.00 182.22 ? 756 PHE A N   1 
ATOM   5466  C CA  . PHE A 1 736 ? 142.029 118.226 182.860 1.00 190.25 ? 756 PHE A CA  1 
ATOM   5467  C C   . PHE A 1 736 ? 142.552 118.554 184.257 1.00 194.41 ? 756 PHE A C   1 
ATOM   5468  O O   . PHE A 1 736 ? 141.921 118.188 185.248 1.00 196.26 ? 756 PHE A O   1 
ATOM   5469  C CB  . PHE A 1 736 ? 142.844 117.094 182.224 1.00 190.89 ? 756 PHE A CB  1 
ATOM   5470  C CG  . PHE A 1 736 ? 142.221 116.429 181.020 1.00 191.89 ? 756 PHE A CG  1 
ATOM   5471  C CD1 . PHE A 1 736 ? 140.868 116.560 180.734 1.00 193.14 ? 756 PHE A CD1 1 
ATOM   5472  C CD2 . PHE A 1 736 ? 143.003 115.676 180.156 1.00 190.91 ? 756 PHE A CD2 1 
ATOM   5473  C CE1 . PHE A 1 736 ? 140.314 115.941 179.622 1.00 193.25 ? 756 PHE A CE1 1 
ATOM   5474  C CE2 . PHE A 1 736 ? 142.448 115.061 179.044 1.00 191.16 ? 756 PHE A CE2 1 
ATOM   5475  C CZ  . PHE A 1 736 ? 141.105 115.196 178.778 1.00 192.53 ? 756 PHE A CZ  1 
ATOM   5476  N N   . TYR A 1 737 ? 143.694 119.250 184.332 1.00 196.84 ? 757 TYR A N   1 
ATOM   5477  C CA  . TYR A 1 737 ? 144.314 119.559 185.611 1.00 200.06 ? 757 TYR A CA  1 
ATOM   5478  C C   . TYR A 1 737 ? 143.480 120.565 186.400 1.00 196.95 ? 757 TYR A C   1 
ATOM   5479  O O   . TYR A 1 737 ? 143.362 120.439 187.618 1.00 198.14 ? 757 TYR A O   1 
ATOM   5480  C CB  . TYR A 1 737 ? 145.748 120.059 185.426 1.00 204.79 ? 757 TYR A CB  1 
ATOM   5481  C CG  . TYR A 1 737 ? 146.721 118.988 185.005 1.00 210.80 ? 757 TYR A CG  1 
ATOM   5482  C CD1 . TYR A 1 737 ? 146.870 117.822 185.741 1.00 213.64 ? 757 TYR A CD1 1 
ATOM   5483  C CD2 . TYR A 1 737 ? 147.503 119.139 183.871 1.00 213.68 ? 757 TYR A CD2 1 
ATOM   5484  C CE1 . TYR A 1 737 ? 147.767 116.836 185.362 1.00 216.27 ? 757 TYR A CE1 1 
ATOM   5485  C CE2 . TYR A 1 737 ? 148.400 118.160 183.473 1.00 215.18 ? 757 TYR A CE2 1 
ATOM   5486  C CZ  . TYR A 1 737 ? 148.539 117.006 184.225 1.00 217.20 ? 757 TYR A CZ  1 
ATOM   5487  O OH  . TYR A 1 737 ? 149.427 116.029 183.841 1.00 217.20 ? 757 TYR A OH  1 
ATOM   5488  N N   . ALA A 1 738 ? 142.884 121.547 185.709 1.00 192.96 ? 758 ALA A N   1 
ATOM   5489  C CA  . ALA A 1 738 ? 142.054 122.543 186.370 1.00 192.70 ? 758 ALA A CA  1 
ATOM   5490  C C   . ALA A 1 738 ? 140.796 121.880 186.934 1.00 194.36 ? 758 ALA A C   1 
ATOM   5491  O O   . ALA A 1 738 ? 140.393 122.180 188.057 1.00 192.18 ? 758 ALA A O   1 
ATOM   5492  C CB  . ALA A 1 738 ? 141.716 123.662 185.415 1.00 193.08 ? 758 ALA A CB  1 
ATOM   5493  N N   . PHE A 1 739 ? 140.213 120.951 186.164 1.00 199.55 ? 759 PHE A N   1 
ATOM   5494  C CA  . PHE A 1 739 ? 139.027 120.238 186.614 1.00 206.05 ? 759 PHE A CA  1 
ATOM   5495  C C   . PHE A 1 739 ? 139.376 119.387 187.833 1.00 205.80 ? 759 PHE A C   1 
ATOM   5496  O O   . PHE A 1 739 ? 138.543 119.211 188.722 1.00 203.22 ? 759 PHE A O   1 
ATOM   5497  C CB  . PHE A 1 739 ? 138.413 119.400 185.490 1.00 211.09 ? 759 PHE A CB  1 
ATOM   5498  C CG  . PHE A 1 739 ? 137.086 118.761 185.821 1.00 215.44 ? 759 PHE A CG  1 
ATOM   5499  C CD1 . PHE A 1 739 ? 135.949 119.529 186.021 1.00 218.11 ? 759 PHE A CD1 1 
ATOM   5500  C CD2 . PHE A 1 739 ? 136.989 117.387 185.983 1.00 218.66 ? 759 PHE A CD2 1 
ATOM   5501  C CE1 . PHE A 1 739 ? 134.737 118.934 186.338 1.00 221.03 ? 759 PHE A CE1 1 
ATOM   5502  C CE2 . PHE A 1 739 ? 135.776 116.793 186.299 1.00 220.79 ? 759 PHE A CE2 1 
ATOM   5503  C CZ  . PHE A 1 739 ? 134.653 117.567 186.478 1.00 221.60 ? 759 PHE A CZ  1 
ATOM   5504  N N   . LYS A 1 740 ? 140.610 118.862 187.861 1.00 206.36 ? 760 LYS A N   1 
ATOM   5505  C CA  . LYS A 1 740 ? 141.094 118.092 188.999 1.00 205.91 ? 760 LYS A CA  1 
ATOM   5506  C C   . LYS A 1 740 ? 141.177 118.985 190.236 1.00 203.65 ? 760 LYS A C   1 
ATOM   5507  O O   . LYS A 1 740 ? 140.857 118.530 191.334 1.00 204.07 ? 760 LYS A O   1 
ATOM   5508  C CB  . LYS A 1 740 ? 142.453 117.453 188.690 1.00 205.02 ? 760 LYS A CB  1 
ATOM   5509  C CG  . LYS A 1 740 ? 142.402 116.205 187.818 1.00 205.35 ? 760 LYS A CG  1 
ATOM   5510  C CD  . LYS A 1 740 ? 143.737 115.838 187.199 1.00 205.76 ? 760 LYS A CD  1 
ATOM   5511  C CE  . LYS A 1 740 ? 143.597 114.867 186.046 1.00 206.40 ? 760 LYS A CE  1 
ATOM   5512  N NZ  . LYS A 1 740 ? 144.894 114.631 185.369 1.00 206.11 ? 760 LYS A NZ  1 
ATOM   5513  N N   . THR A 1 741 ? 141.584 120.247 190.051 1.00 199.35 ? 761 THR A N   1 
ATOM   5514  C CA  . THR A 1 741 ? 141.686 121.180 191.162 1.00 196.64 ? 761 THR A CA  1 
ATOM   5515  C C   . THR A 1 741 ? 140.308 121.756 191.492 1.00 200.41 ? 761 THR A C   1 
ATOM   5516  O O   . THR A 1 741 ? 139.866 121.710 192.637 1.00 200.23 ? 761 THR A O   1 
ATOM   5517  C CB  . THR A 1 741 ? 142.670 122.309 190.849 1.00 192.15 ? 761 THR A CB  1 
ATOM   5518  O OG1 . THR A 1 741 ? 143.868 121.739 190.319 1.00 190.20 ? 761 THR A OG1 1 
ATOM   5519  C CG2 . THR A 1 741 ? 142.975 123.141 192.071 1.00 191.02 ? 761 THR A CG2 1 
ATOM   5520  N N   . ARG A 1 742 ? 139.649 122.295 190.463 1.00 205.00 ? 762 ARG A N   1 
ATOM   5521  C CA  . ARG A 1 742 ? 138.299 122.835 190.562 1.00 209.35 ? 762 ARG A CA  1 
ATOM   5522  C C   . ARG A 1 742 ? 138.256 123.976 191.583 1.00 205.74 ? 762 ARG A C   1 
ATOM   5523  O O   . ARG A 1 742 ? 138.782 125.056 191.318 1.00 201.94 ? 762 ARG A O   1 
ATOM   5524  C CB  . ARG A 1 742 ? 137.300 121.702 190.830 1.00 214.45 ? 762 ARG A CB  1 
ATOM   5525  C CG  . ARG A 1 742 ? 135.865 122.055 190.470 1.00 219.22 ? 762 ARG A CG  1 
ATOM   5526  C CD  . ARG A 1 742 ? 134.864 121.002 190.888 1.00 223.54 ? 762 ARG A CD  1 
ATOM   5527  N NE  . ARG A 1 742 ? 133.564 121.263 190.285 1.00 225.94 ? 762 ARG A NE  1 
ATOM   5528  C CZ  . ARG A 1 742 ? 132.562 121.913 190.872 1.00 226.73 ? 762 ARG A CZ  1 
ATOM   5529  N NH1 . ARG A 1 742 ? 132.706 122.420 192.085 1.00 226.37 ? 762 ARG A NH1 1 
ATOM   5530  N NH2 . ARG A 1 742 ? 131.415 122.070 190.232 1.00 225.77 ? 762 ARG A NH2 1 
ATOM   5531  N N   . ASN A 1 743 ? 137.595 123.756 192.731 1.00 205.26 ? 763 ASN A N   1 
ATOM   5532  C CA  . ASN A 1 743 ? 137.259 124.824 193.659 1.00 205.99 ? 763 ASN A CA  1 
ATOM   5533  C C   . ASN A 1 743 ? 137.968 124.629 194.997 1.00 204.09 ? 763 ASN A C   1 
ATOM   5534  O O   . ASN A 1 743 ? 137.366 124.818 196.054 1.00 203.93 ? 763 ASN A O   1 
ATOM   5535  C CB  . ASN A 1 743 ? 135.743 124.913 193.871 1.00 208.82 ? 763 ASN A CB  1 
ATOM   5536  C CG  . ASN A 1 743 ? 134.973 125.058 192.576 1.00 209.91 ? 763 ASN A CG  1 
ATOM   5537  O OD1 . ASN A 1 743 ? 135.558 125.056 191.495 1.00 208.68 ? 763 ASN A OD1 1 
ATOM   5538  N ND2 . ASN A 1 743 ? 133.658 125.180 192.674 1.00 209.78 ? 763 ASN A ND2 1 
ATOM   5539  N N   . VAL A 1 744 ? 139.258 124.287 194.963 1.00 203.30 ? 764 VAL A N   1 
ATOM   5540  C CA  . VAL A 1 744 ? 140.036 124.128 196.179 1.00 204.95 ? 764 VAL A CA  1 
ATOM   5541  C C   . VAL A 1 744 ? 140.312 125.510 196.766 1.00 204.15 ? 764 VAL A C   1 
ATOM   5542  O O   . VAL A 1 744 ? 140.695 126.419 196.036 1.00 203.58 ? 764 VAL A O   1 
ATOM   5543  C CB  . VAL A 1 744 ? 141.336 123.349 195.902 1.00 205.74 ? 764 VAL A CB  1 
ATOM   5544  C CG1 . VAL A 1 744 ? 142.380 123.533 196.997 1.00 205.03 ? 764 VAL A CG1 1 
ATOM   5545  C CG2 . VAL A 1 744 ? 141.047 121.874 195.683 1.00 205.91 ? 764 VAL A CG2 1 
ATOM   5546  N N   . PRO A 1 745 ? 140.155 125.707 198.096 1.00 203.63 ? 765 PRO A N   1 
ATOM   5547  C CA  . PRO A 1 745 ? 140.502 126.978 198.727 1.00 201.57 ? 765 PRO A CA  1 
ATOM   5548  C C   . PRO A 1 745 ? 141.958 127.360 198.459 1.00 199.07 ? 765 PRO A C   1 
ATOM   5549  O O   . PRO A 1 745 ? 142.857 126.527 198.558 1.00 199.26 ? 765 PRO A O   1 
ATOM   5550  C CB  . PRO A 1 745 ? 140.239 126.776 200.230 1.00 203.23 ? 765 PRO A CB  1 
ATOM   5551  C CG  . PRO A 1 745 ? 139.969 125.286 200.419 1.00 204.16 ? 765 PRO A CG  1 
ATOM   5552  C CD  . PRO A 1 745 ? 139.636 124.722 199.054 1.00 204.69 ? 765 PRO A CD  1 
ATOM   5553  N N   . ALA A 1 746 ? 142.164 128.626 198.087 1.00 197.09 ? 766 ALA A N   1 
ATOM   5554  C CA  . ALA A 1 746 ? 143.482 129.141 197.755 1.00 196.46 ? 766 ALA A CA  1 
ATOM   5555  C C   . ALA A 1 746 ? 143.574 130.599 198.202 1.00 195.54 ? 766 ALA A C   1 
ATOM   5556  O O   . ALA A 1 746 ? 142.790 131.033 199.047 1.00 195.05 ? 766 ALA A O   1 
ATOM   5557  C CB  . ALA A 1 746 ? 143.710 128.975 196.272 1.00 196.70 ? 766 ALA A CB  1 
ATOM   5558  N N   . ASN A 1 747 ? 144.520 131.351 197.624 1.00 193.98 ? 767 ASN A N   1 
ATOM   5559  C CA  . ASN A 1 747 ? 144.636 132.779 197.876 1.00 193.54 ? 767 ASN A CA  1 
ATOM   5560  C C   . ASN A 1 747 ? 143.431 133.500 197.271 1.00 194.96 ? 767 ASN A C   1 
ATOM   5561  O O   . ASN A 1 747 ? 143.530 134.084 196.199 1.00 194.99 ? 767 ASN A O   1 
ATOM   5562  C CB  . ASN A 1 747 ? 145.968 133.309 197.341 1.00 192.57 ? 767 ASN A CB  1 
ATOM   5563  C CG  . ASN A 1 747 ? 146.123 134.805 197.503 1.00 191.81 ? 767 ASN A CG  1 
ATOM   5564  O OD1 . ASN A 1 747 ? 146.167 135.536 196.516 1.00 192.25 ? 767 ASN A OD1 1 
ATOM   5565  N ND2 . ASN A 1 747 ? 146.187 135.265 198.741 1.00 191.34 ? 767 ASN A ND2 1 
ATOM   5566  N N   . PHE A 1 748 ? 142.294 133.438 197.974 1.00 197.86 ? 768 PHE A N   1 
ATOM   5567  C CA  . PHE A 1 748 ? 141.012 133.940 197.497 1.00 201.30 ? 768 PHE A CA  1 
ATOM   5568  C C   . PHE A 1 748 ? 140.509 133.117 196.308 1.00 201.02 ? 768 PHE A C   1 
ATOM   5569  O O   . PHE A 1 748 ? 139.738 133.609 195.481 1.00 198.16 ? 768 PHE A O   1 
ATOM   5570  C CB  . PHE A 1 748 ? 141.093 135.431 197.162 1.00 203.82 ? 768 PHE A CB  1 
ATOM   5571  C CG  . PHE A 1 748 ? 139.767 136.149 197.218 1.00 208.36 ? 768 PHE A CG  1 
ATOM   5572  C CD1 . PHE A 1 748 ? 139.135 136.379 198.432 1.00 209.77 ? 768 PHE A CD1 1 
ATOM   5573  C CD2 . PHE A 1 748 ? 139.135 136.570 196.057 1.00 210.83 ? 768 PHE A CD2 1 
ATOM   5574  C CE1 . PHE A 1 748 ? 137.912 137.031 198.484 1.00 210.70 ? 768 PHE A CE1 1 
ATOM   5575  C CE2 . PHE A 1 748 ? 137.911 137.222 196.111 1.00 210.95 ? 768 PHE A CE2 1 
ATOM   5576  C CZ  . PHE A 1 748 ? 137.302 137.451 197.324 1.00 210.81 ? 768 PHE A CZ  1 
ATOM   5577  N N   . ASN A 1 749 ? 140.910 131.840 196.270 1.00 203.54 ? 769 ASN A N   1 
ATOM   5578  C CA  . ASN A 1 749 ? 140.319 130.847 195.382 1.00 205.82 ? 769 ASN A CA  1 
ATOM   5579  C C   . ASN A 1 749 ? 140.462 131.282 193.922 1.00 201.12 ? 769 ASN A C   1 
ATOM   5580  O O   . ASN A 1 749 ? 139.471 131.558 193.245 1.00 202.11 ? 769 ASN A O   1 
ATOM   5581  C CB  . ASN A 1 749 ? 138.860 130.554 195.755 1.00 208.02 ? 769 ASN A CB  1 
ATOM   5582  C CG  . ASN A 1 749 ? 138.697 129.998 197.156 1.00 208.37 ? 769 ASN A CG  1 
ATOM   5583  O OD1 . ASN A 1 749 ? 139.540 130.221 198.022 1.00 208.23 ? 769 ASN A OD1 1 
ATOM   5584  N ND2 . ASN A 1 749 ? 137.600 129.298 197.398 1.00 208.00 ? 769 ASN A ND2 1 
ATOM   5585  N N   . GLU A 1 750 ? 141.707 131.297 193.429 1.00 191.20 ? 770 GLU A N   1 
ATOM   5586  C CA  . GLU A 1 750 ? 141.971 131.569 192.022 1.00 183.43 ? 770 GLU A CA  1 
ATOM   5587  C C   . GLU A 1 750 ? 141.430 130.442 191.141 1.00 176.71 ? 770 GLU A C   1 
ATOM   5588  O O   . GLU A 1 750 ? 140.936 130.706 190.051 1.00 174.14 ? 770 GLU A O   1 
ATOM   5589  C CB  . GLU A 1 750 ? 143.467 131.733 191.736 1.00 184.15 ? 770 GLU A CB  1 
ATOM   5590  C CG  . GLU A 1 750 ? 144.061 133.025 192.261 1.00 187.30 ? 770 GLU A CG  1 
ATOM   5591  C CD  . GLU A 1 750 ? 144.627 132.920 193.665 1.00 190.33 ? 770 GLU A CD  1 
ATOM   5592  O OE1 . GLU A 1 750 ? 145.685 133.529 193.925 1.00 189.91 ? 770 GLU A OE1 1 
ATOM   5593  O OE2 . GLU A 1 750 ? 144.024 132.203 194.484 1.00 191.70 ? 770 GLU A OE2 1 
ATOM   5594  N N   . ALA A 1 751 ? 141.534 129.197 191.624 1.00 173.53 ? 771 ALA A N   1 
ATOM   5595  C CA  . ALA A 1 751 ? 141.332 128.009 190.808 1.00 173.51 ? 771 ALA A CA  1 
ATOM   5596  C C   . ALA A 1 751 ? 139.988 128.039 190.079 1.00 170.38 ? 771 ALA A C   1 
ATOM   5597  O O   . ALA A 1 751 ? 139.912 127.646 188.913 1.00 169.53 ? 771 ALA A O   1 
ATOM   5598  C CB  . ALA A 1 751 ? 141.452 126.782 191.677 1.00 174.07 ? 771 ALA A CB  1 
ATOM   5599  N N   . LYS A 1 752 ? 138.932 128.488 190.768 1.00 165.79 ? 772 LYS A N   1 
ATOM   5600  C CA  . LYS A 1 752 ? 137.607 128.524 190.167 1.00 163.27 ? 772 LYS A CA  1 
ATOM   5601  C C   . LYS A 1 752 ? 137.593 129.517 189.004 1.00 157.70 ? 772 LYS A C   1 
ATOM   5602  O O   . LYS A 1 752 ? 137.039 129.219 187.948 1.00 157.55 ? 772 LYS A O   1 
ATOM   5603  C CB  . LYS A 1 752 ? 136.527 128.848 191.204 1.00 164.69 ? 772 LYS A CB  1 
ATOM   5604  C CG  . LYS A 1 752 ? 136.645 130.206 191.882 1.00 165.05 ? 772 LYS A CG  1 
ATOM   5605  C CD  . LYS A 1 752 ? 135.361 130.700 192.511 1.00 164.75 ? 772 LYS A CD  1 
ATOM   5606  C CE  . LYS A 1 752 ? 134.309 131.106 191.499 1.00 164.62 ? 772 LYS A CE  1 
ATOM   5607  N NZ  . LYS A 1 752 ? 133.065 131.568 192.160 1.00 164.44 ? 772 LYS A NZ  1 
ATOM   5608  N N   . TYR A 1 753 ? 138.227 130.681 189.190 1.00 150.00 ? 773 TYR A N   1 
ATOM   5609  C CA  . TYR A 1 753 ? 138.284 131.694 188.145 1.00 144.40 ? 773 TYR A CA  1 
ATOM   5610  C C   . TYR A 1 753 ? 139.098 131.185 186.958 1.00 136.35 ? 773 TYR A C   1 
ATOM   5611  O O   . TYR A 1 753 ? 138.728 131.426 185.814 1.00 133.55 ? 773 TYR A O   1 
ATOM   5612  C CB  . TYR A 1 753 ? 138.844 133.017 188.677 1.00 146.61 ? 773 TYR A CB  1 
ATOM   5613  C CG  . TYR A 1 753 ? 137.816 133.911 189.326 1.00 152.63 ? 773 TYR A CG  1 
ATOM   5614  C CD1 . TYR A 1 753 ? 136.980 133.430 190.320 1.00 156.01 ? 773 TYR A CD1 1 
ATOM   5615  C CD2 . TYR A 1 753 ? 137.670 135.237 188.944 1.00 157.47 ? 773 TYR A CD2 1 
ATOM   5616  C CE1 . TYR A 1 753 ? 136.031 134.239 190.924 1.00 160.47 ? 773 TYR A CE1 1 
ATOM   5617  C CE2 . TYR A 1 753 ? 136.723 136.059 189.535 1.00 160.81 ? 773 TYR A CE2 1 
ATOM   5618  C CZ  . TYR A 1 753 ? 135.900 135.560 190.529 1.00 161.68 ? 773 TYR A CZ  1 
ATOM   5619  O OH  . TYR A 1 753 ? 134.960 136.369 191.122 1.00 159.76 ? 773 TYR A OH  1 
ATOM   5620  N N   . ILE A 1 754 ? 140.186 130.460 187.234 1.00 131.63 ? 774 ILE A N   1 
ATOM   5621  C CA  . ILE A 1 754 ? 141.036 129.925 186.183 1.00 129.26 ? 774 ILE A CA  1 
ATOM   5622  C C   . ILE A 1 754 ? 140.249 128.888 185.383 1.00 126.68 ? 774 ILE A C   1 
ATOM   5623  O O   . ILE A 1 754 ? 140.383 128.816 184.162 1.00 126.46 ? 774 ILE A O   1 
ATOM   5624  C CB  . ILE A 1 754 ? 142.337 129.322 186.756 1.00 129.84 ? 774 ILE A CB  1 
ATOM   5625  C CG1 . ILE A 1 754 ? 143.055 130.278 187.712 1.00 130.23 ? 774 ILE A CG1 1 
ATOM   5626  C CG2 . ILE A 1 754 ? 143.260 128.875 185.636 1.00 130.05 ? 774 ILE A CG2 1 
ATOM   5627  C CD1 . ILE A 1 754 ? 143.205 131.673 187.173 1.00 129.03 ? 774 ILE A CD1 1 
ATOM   5628  N N   . ALA A 1 755 ? 139.438 128.083 186.082 1.00 124.66 ? 775 ALA A N   1 
ATOM   5629  C CA  . ALA A 1 755 ? 138.630 127.070 185.421 1.00 123.92 ? 775 ALA A CA  1 
ATOM   5630  C C   . ALA A 1 755 ? 137.603 127.737 184.505 1.00 122.51 ? 775 ALA A C   1 
ATOM   5631  O O   . ALA A 1 755 ? 137.381 127.284 183.381 1.00 121.43 ? 775 ALA A O   1 
ATOM   5632  C CB  . ALA A 1 755 ? 137.970 126.169 186.436 1.00 125.16 ? 775 ALA A CB  1 
ATOM   5633  N N   . PHE A 1 756 ? 136.976 128.813 184.996 1.00 123.29 ? 776 PHE A N   1 
ATOM   5634  C CA  . PHE A 1 756 ? 136.021 129.569 184.203 1.00 125.01 ? 776 PHE A CA  1 
ATOM   5635  C C   . PHE A 1 756 ? 136.699 130.063 182.926 1.00 117.84 ? 776 PHE A C   1 
ATOM   5636  O O   . PHE A 1 756 ? 136.173 129.876 181.832 1.00 116.09 ? 776 PHE A O   1 
ATOM   5637  C CB  . PHE A 1 756 ? 135.453 130.731 185.023 1.00 131.63 ? 776 PHE A CB  1 
ATOM   5638  C CG  . PHE A 1 756 ? 134.221 131.409 184.473 1.00 138.55 ? 776 PHE A CG  1 
ATOM   5639  C CD1 . PHE A 1 756 ? 133.518 130.897 183.388 1.00 142.71 ? 776 PHE A CD1 1 
ATOM   5640  C CD2 . PHE A 1 756 ? 133.755 132.574 185.062 1.00 141.13 ? 776 PHE A CD2 1 
ATOM   5641  C CE1 . PHE A 1 756 ? 132.385 131.537 182.909 1.00 144.11 ? 776 PHE A CE1 1 
ATOM   5642  C CE2 . PHE A 1 756 ? 132.623 133.214 184.581 1.00 144.52 ? 776 PHE A CE2 1 
ATOM   5643  C CZ  . PHE A 1 756 ? 131.940 132.695 183.505 1.00 145.57 ? 776 PHE A CZ  1 
ATOM   5644  N N   . ALA A 1 757 ? 137.875 130.682 183.087 1.00 112.98 ? 777 ALA A N   1 
ATOM   5645  C CA  . ALA A 1 757 ? 138.633 131.228 181.973 1.00 110.12 ? 777 ALA A CA  1 
ATOM   5646  C C   . ALA A 1 757 ? 138.967 130.131 180.968 1.00 107.05 ? 777 ALA A C   1 
ATOM   5647  O O   . ALA A 1 757 ? 138.884 130.363 179.764 1.00 106.35 ? 777 ALA A O   1 
ATOM   5648  C CB  . ALA A 1 757 ? 139.894 131.891 182.469 1.00 110.01 ? 777 ALA A CB  1 
ATOM   5649  N N   . MET A 1 758 ? 139.347 128.950 181.471 1.00 106.50 ? 778 MET A N   1 
ATOM   5650  C CA  . MET A 1 758 ? 139.784 127.867 180.608 1.00 109.50 ? 778 MET A CA  1 
ATOM   5651  C C   . MET A 1 758 ? 138.611 127.352 179.777 1.00 109.16 ? 778 MET A C   1 
ATOM   5652  O O   . MET A 1 758 ? 138.763 127.110 178.581 1.00 109.90 ? 778 MET A O   1 
ATOM   5653  C CB  . MET A 1 758 ? 140.395 126.709 181.407 1.00 114.17 ? 778 MET A CB  1 
ATOM   5654  C CG  . MET A 1 758 ? 141.766 127.010 181.986 1.00 116.94 ? 778 MET A CG  1 
ATOM   5655  S SD  . MET A 1 758 ? 142.753 128.206 181.044 1.00 120.38 ? 778 MET A SD  1 
ATOM   5656  C CE  . MET A 1 758 ? 143.166 127.260 179.576 1.00 122.35 ? 778 MET A CE  1 
ATOM   5657  N N   . TYR A 1 759 ? 137.440 127.204 180.409 1.00 108.40 ? 779 TYR A N   1 
ATOM   5658  C CA  . TYR A 1 759 ? 136.256 126.761 179.691 1.00 108.72 ? 779 TYR A CA  1 
ATOM   5659  C C   . TYR A 1 759 ? 135.904 127.770 178.597 1.00 104.37 ? 779 TYR A C   1 
ATOM   5660  O O   . TYR A 1 759 ? 135.642 127.383 177.456 1.00 103.92 ? 779 TYR A O   1 
ATOM   5661  C CB  . TYR A 1 759 ? 135.073 126.543 180.637 1.00 112.84 ? 779 TYR A CB  1 
ATOM   5662  C CG  . TYR A 1 759 ? 135.343 125.666 181.835 1.00 115.41 ? 779 TYR A CG  1 
ATOM   5663  C CD1 . TYR A 1 759 ? 136.247 124.612 181.788 1.00 117.12 ? 779 TYR A CD1 1 
ATOM   5664  C CD2 . TYR A 1 759 ? 134.673 125.888 183.025 1.00 117.22 ? 779 TYR A CD2 1 
ATOM   5665  C CE1 . TYR A 1 759 ? 136.487 123.819 182.898 1.00 119.94 ? 779 TYR A CE1 1 
ATOM   5666  C CE2 . TYR A 1 759 ? 134.897 125.101 184.144 1.00 119.59 ? 779 TYR A CE2 1 
ATOM   5667  C CZ  . TYR A 1 759 ? 135.810 124.063 184.081 1.00 121.70 ? 779 TYR A CZ  1 
ATOM   5668  O OH  . TYR A 1 759 ? 136.041 123.275 185.184 1.00 122.85 ? 779 TYR A OH  1 
ATOM   5669  N N   . THR A 1 760 ? 135.920 129.064 178.942 1.00 99.57  ? 780 THR A N   1 
ATOM   5670  C CA  . THR A 1 760 ? 135.487 130.076 177.991 1.00 95.65  ? 780 THR A CA  1 
ATOM   5671  C C   . THR A 1 760 ? 136.475 130.156 176.829 1.00 94.04  ? 780 THR A C   1 
ATOM   5672  O O   . THR A 1 760 ? 136.063 130.369 175.691 1.00 92.19  ? 780 THR A O   1 
ATOM   5673  C CB  . THR A 1 760 ? 135.271 131.455 178.625 1.00 96.18  ? 780 THR A CB  1 
ATOM   5674  O OG1 . THR A 1 760 ? 136.543 132.055 178.857 1.00 94.89  ? 780 THR A OG1 1 
ATOM   5675  C CG2 . THR A 1 760 ? 134.446 131.409 179.893 1.00 98.35  ? 780 THR A CG2 1 
ATOM   5676  N N   . THR A 1 761 ? 137.772 129.985 177.108 1.00 95.65  ? 781 THR A N   1 
ATOM   5677  C CA  . THR A 1 761 ? 138.774 130.097 176.058 1.00 97.27  ? 781 THR A CA  1 
ATOM   5678  C C   . THR A 1 761 ? 138.695 128.888 175.126 1.00 96.94  ? 781 THR A C   1 
ATOM   5679  O O   . THR A 1 761 ? 138.916 129.023 173.927 1.00 96.20  ? 781 THR A O   1 
ATOM   5680  C CB  . THR A 1 761 ? 140.184 130.295 176.628 1.00 98.80  ? 781 THR A CB  1 
ATOM   5681  O OG1 . THR A 1 761 ? 141.013 130.717 175.546 1.00 98.89  ? 781 THR A OG1 1 
ATOM   5682  C CG2 . THR A 1 761 ? 140.761 129.056 177.276 1.00 99.96  ? 781 THR A CG2 1 
ATOM   5683  N N   . CYS A 1 762 ? 138.391 127.707 175.672 1.00 97.48  ? 782 CYS A N   1 
ATOM   5684  C CA  . CYS A 1 762 ? 138.184 126.530 174.841 1.00 98.61  ? 782 CYS A CA  1 
ATOM   5685  C C   . CYS A 1 762 ? 136.994 126.766 173.910 1.00 96.84  ? 782 CYS A C   1 
ATOM   5686  O O   . CYS A 1 762 ? 137.071 126.466 172.722 1.00 96.58  ? 782 CYS A O   1 
ATOM   5687  C CB  . CYS A 1 762 ? 137.974 125.277 175.683 1.00 100.01 ? 782 CYS A CB  1 
ATOM   5688  S SG  . CYS A 1 762 ? 138.100 123.741 174.730 1.00 103.66 ? 782 CYS A SG  1 
ATOM   5689  N N   . ILE A 1 763 ? 135.904 127.321 174.456 1.00 93.98  ? 783 ILE A N   1 
ATOM   5690  C CA  . ILE A 1 763 ? 134.720 127.635 173.667 1.00 91.54  ? 783 ILE A CA  1 
ATOM   5691  C C   . ILE A 1 763 ? 135.089 128.613 172.549 1.00 83.71  ? 783 ILE A C   1 
ATOM   5692  O O   . ILE A 1 763 ? 134.671 128.428 171.410 1.00 81.80  ? 783 ILE A O   1 
ATOM   5693  C CB  . ILE A 1 763 ? 133.573 128.157 174.564 1.00 95.99  ? 783 ILE A CB  1 
ATOM   5694  C CG1 . ILE A 1 763 ? 132.776 126.997 175.172 1.00 99.99  ? 783 ILE A CG1 1 
ATOM   5695  C CG2 . ILE A 1 763 ? 132.655 129.120 173.814 1.00 96.22  ? 783 ILE A CG2 1 
ATOM   5696  C CD1 . ILE A 1 763 ? 131.681 127.419 176.133 1.00 102.24 ? 783 ILE A CD1 1 
ATOM   5697  N N   . ILE A 1 764 ? 135.852 129.657 172.889 1.00 76.44  ? 784 ILE A N   1 
ATOM   5698  C CA  . ILE A 1 764 ? 136.207 130.705 171.943 1.00 71.77  ? 784 ILE A CA  1 
ATOM   5699  C C   . ILE A 1 764 ? 137.013 130.110 170.789 1.00 71.15  ? 784 ILE A C   1 
ATOM   5700  O O   . ILE A 1 764 ? 136.769 130.423 169.625 1.00 71.69  ? 784 ILE A O   1 
ATOM   5701  C CB  . ILE A 1 764 ? 136.994 131.834 172.643 1.00 69.62  ? 784 ILE A CB  1 
ATOM   5702  C CG1 . ILE A 1 764 ? 136.111 132.657 173.583 1.00 70.09  ? 784 ILE A CG1 1 
ATOM   5703  C CG2 . ILE A 1 764 ? 137.690 132.730 171.628 1.00 69.04  ? 784 ILE A CG2 1 
ATOM   5704  C CD1 . ILE A 1 764 ? 136.889 133.526 174.550 1.00 70.65  ? 784 ILE A CD1 1 
ATOM   5705  N N   . TRP A 1 765 ? 138.005 129.285 171.135 1.00 72.82  ? 785 TRP A N   1 
ATOM   5706  C CA  . TRP A 1 765 ? 138.817 128.614 170.138 1.00 75.01  ? 785 TRP A CA  1 
ATOM   5707  C C   . TRP A 1 765 ? 137.937 127.807 169.188 1.00 74.50  ? 785 TRP A C   1 
ATOM   5708  O O   . TRP A 1 765 ? 138.134 127.851 167.975 1.00 73.81  ? 785 TRP A O   1 
ATOM   5709  C CB  . TRP A 1 765 ? 139.867 127.726 170.813 1.00 78.10  ? 785 TRP A CB  1 
ATOM   5710  C CG  . TRP A 1 765 ? 141.130 128.443 171.168 1.00 80.77  ? 785 TRP A CG  1 
ATOM   5711  C CD1 . TRP A 1 765 ? 141.269 129.626 171.834 1.00 81.22  ? 785 TRP A CD1 1 
ATOM   5712  C CD2 . TRP A 1 765 ? 142.460 128.004 170.849 1.00 82.44  ? 785 TRP A CD2 1 
ATOM   5713  N NE1 . TRP A 1 765 ? 142.595 129.948 171.955 1.00 80.65  ? 785 TRP A NE1 1 
ATOM   5714  C CE2 . TRP A 1 765 ? 143.349 128.974 171.359 1.00 81.84  ? 785 TRP A CE2 1 
ATOM   5715  C CE3 . TRP A 1 765 ? 142.983 126.886 170.190 1.00 83.76  ? 785 TRP A CE3 1 
ATOM   5716  C CZ2 . TRP A 1 765 ? 144.731 128.855 171.228 1.00 83.14  ? 785 TRP A CZ2 1 
ATOM   5717  C CZ3 . TRP A 1 765 ? 144.349 126.772 170.057 1.00 84.61  ? 785 TRP A CZ3 1 
ATOM   5718  C CH2 . TRP A 1 765 ? 145.208 127.744 170.570 1.00 84.94  ? 785 TRP A CH2 1 
ATOM   5719  N N   . LEU A 1 766 ? 136.973 127.068 169.747 1.00 75.31  ? 786 LEU A N   1 
ATOM   5720  C CA  . LEU A 1 766 ? 136.160 126.175 168.938 1.00 75.64  ? 786 LEU A CA  1 
ATOM   5721  C C   . LEU A 1 766 ? 135.173 126.972 168.089 1.00 70.54  ? 786 LEU A C   1 
ATOM   5722  O O   . LEU A 1 766 ? 134.728 126.469 167.060 1.00 70.16  ? 786 LEU A O   1 
ATOM   5723  C CB  . LEU A 1 766 ? 135.430 125.173 169.840 1.00 79.84  ? 786 LEU A CB  1 
ATOM   5724  C CG  . LEU A 1 766 ? 136.312 124.119 170.511 1.00 83.06  ? 786 LEU A CG  1 
ATOM   5725  C CD1 . LEU A 1 766 ? 135.466 123.143 171.316 1.00 85.03  ? 786 LEU A CD1 1 
ATOM   5726  C CD2 . LEU A 1 766 ? 137.158 123.368 169.491 1.00 83.55  ? 786 LEU A CD2 1 
ATOM   5727  N N   . ALA A 1 767 ? 134.845 128.205 168.500 1.00 65.95  ? 787 ALA A N   1 
ATOM   5728  C CA  . ALA A 1 767 ? 133.771 128.956 167.868 1.00 63.53  ? 787 ALA A CA  1 
ATOM   5729  C C   . ALA A 1 767 ? 134.138 129.389 166.448 1.00 61.45  ? 787 ALA A C   1 
ATOM   5730  O O   . ALA A 1 767 ? 133.277 129.394 165.572 1.00 62.13  ? 787 ALA A O   1 
ATOM   5731  C CB  . ALA A 1 767 ? 133.406 130.149 168.718 1.00 63.98  ? 787 ALA A CB  1 
ATOM   5732  N N   . PHE A 1 768 ? 135.405 129.762 166.223 1.00 60.31  ? 788 PHE A N   1 
ATOM   5733  C CA  . PHE A 1 768 ? 135.790 130.407 164.975 1.00 59.51  ? 788 PHE A CA  1 
ATOM   5734  C C   . PHE A 1 768 ? 136.188 129.392 163.901 1.00 62.53  ? 788 PHE A C   1 
ATOM   5735  O O   . PHE A 1 768 ? 136.639 129.797 162.833 1.00 63.37  ? 788 PHE A O   1 
ATOM   5736  C CB  . PHE A 1 768 ? 136.958 131.374 165.187 1.00 57.62  ? 788 PHE A CB  1 
ATOM   5737  C CG  . PHE A 1 768 ? 136.643 132.610 165.985 1.00 56.86  ? 788 PHE A CG  1 
ATOM   5738  C CD1 . PHE A 1 768 ? 136.555 132.561 167.367 1.00 57.10  ? 788 PHE A CD1 1 
ATOM   5739  C CD2 . PHE A 1 768 ? 136.424 133.823 165.355 1.00 57.76  ? 788 PHE A CD2 1 
ATOM   5740  C CE1 . PHE A 1 768 ? 136.270 133.701 168.103 1.00 57.97  ? 788 PHE A CE1 1 
ATOM   5741  C CE2 . PHE A 1 768 ? 136.137 134.963 166.091 1.00 58.66  ? 788 PHE A CE2 1 
ATOM   5742  C CZ  . PHE A 1 768 ? 136.059 134.901 167.465 1.00 58.54  ? 788 PHE A CZ  1 
ATOM   5743  N N   . VAL A 1 769 ? 136.037 128.086 164.169 1.00 64.74  ? 789 VAL A N   1 
ATOM   5744  C CA  . VAL A 1 769 ? 136.589 127.073 163.276 1.00 66.02  ? 789 VAL A CA  1 
ATOM   5745  C C   . VAL A 1 769 ? 135.886 127.121 161.917 1.00 68.50  ? 789 VAL A C   1 
ATOM   5746  O O   . VAL A 1 769 ? 136.557 127.164 160.886 1.00 69.08  ? 789 VAL A O   1 
ATOM   5747  C CB  . VAL A 1 769 ? 136.534 125.663 163.897 1.00 65.44  ? 789 VAL A CB  1 
ATOM   5748  C CG1 . VAL A 1 769 ? 136.945 124.587 162.903 1.00 65.56  ? 789 VAL A CG1 1 
ATOM   5749  C CG2 . VAL A 1 769 ? 137.376 125.574 165.157 1.00 65.90  ? 789 VAL A CG2 1 
ATOM   5750  N N   . PRO A 1 770 ? 134.532 127.093 161.849 1.00 72.70  ? 790 PRO A N   1 
ATOM   5751  C CA  . PRO A 1 770 ? 133.832 127.104 160.563 1.00 75.24  ? 790 PRO A CA  1 
ATOM   5752  C C   . PRO A 1 770 ? 134.076 128.357 159.724 1.00 76.60  ? 790 PRO A C   1 
ATOM   5753  O O   . PRO A 1 770 ? 134.214 128.260 158.506 1.00 75.94  ? 790 PRO A O   1 
ATOM   5754  C CB  . PRO A 1 770 ? 132.343 127.009 160.940 1.00 75.96  ? 790 PRO A CB  1 
ATOM   5755  C CG  . PRO A 1 770 ? 132.341 126.448 162.344 1.00 75.34  ? 790 PRO A CG  1 
ATOM   5756  C CD  . PRO A 1 770 ? 133.595 127.007 162.979 1.00 74.05  ? 790 PRO A CD  1 
ATOM   5757  N N   . ILE A 1 771 ? 134.140 129.530 160.376 1.00 78.39  ? 791 ILE A N   1 
ATOM   5758  C CA  . ILE A 1 771 ? 134.382 130.777 159.665 1.00 81.37  ? 791 ILE A CA  1 
ATOM   5759  C C   . ILE A 1 771 ? 135.828 130.818 159.171 1.00 86.11  ? 791 ILE A C   1 
ATOM   5760  O O   . ILE A 1 771 ? 136.111 131.475 158.175 1.00 87.90  ? 791 ILE A O   1 
ATOM   5761  C CB  . ILE A 1 771 ? 134.047 132.011 160.531 1.00 80.14  ? 791 ILE A CB  1 
ATOM   5762  C CG1 . ILE A 1 771 ? 133.957 133.282 159.679 1.00 81.28  ? 791 ILE A CG1 1 
ATOM   5763  C CG2 . ILE A 1 771 ? 135.033 132.179 161.679 1.00 78.96  ? 791 ILE A CG2 1 
ATOM   5764  C CD1 . ILE A 1 771 ? 133.461 134.500 160.425 1.00 82.64  ? 791 ILE A CD1 1 
ATOM   5765  N N   . TYR A 1 772 ? 136.732 130.121 159.870 1.00 89.42  ? 792 TYR A N   1 
ATOM   5766  C CA  . TYR A 1 772 ? 138.144 130.185 159.542 1.00 91.73  ? 792 TYR A CA  1 
ATOM   5767  C C   . TYR A 1 772 ? 138.479 129.243 158.390 1.00 96.33  ? 792 TYR A C   1 
ATOM   5768  O O   . TYR A 1 772 ? 138.879 129.694 157.321 1.00 95.27  ? 792 TYR A O   1 
ATOM   5769  C CB  . TYR A 1 772 ? 139.020 129.866 160.754 1.00 91.15  ? 792 TYR A CB  1 
ATOM   5770  C CG  . TYR A 1 772 ? 140.330 130.603 160.692 1.00 91.06  ? 792 TYR A CG  1 
ATOM   5771  C CD1 . TYR A 1 772 ? 141.161 130.509 159.587 1.00 92.55  ? 792 TYR A CD1 1 
ATOM   5772  C CD2 . TYR A 1 772 ? 140.697 131.467 161.707 1.00 89.46  ? 792 TYR A CD2 1 
ATOM   5773  C CE1 . TYR A 1 772 ? 142.341 131.229 159.510 1.00 92.04  ? 792 TYR A CE1 1 
ATOM   5774  C CE2 . TYR A 1 772 ? 141.875 132.191 161.650 1.00 89.53  ? 792 TYR A CE2 1 
ATOM   5775  C CZ  . TYR A 1 772 ? 142.703 132.070 160.546 1.00 90.58  ? 792 TYR A CZ  1 
ATOM   5776  O OH  . TYR A 1 772 ? 143.879 132.773 160.446 1.00 89.90  ? 792 TYR A OH  1 
ATOM   5777  N N   . PHE A 1 773 ? 138.296 127.936 158.613 1.00 104.59 ? 793 PHE A N   1 
ATOM   5778  C CA  . PHE A 1 773 ? 138.921 126.920 157.783 1.00 112.09 ? 793 PHE A CA  1 
ATOM   5779  C C   . PHE A 1 773 ? 138.237 126.776 156.425 1.00 118.86 ? 793 PHE A C   1 
ATOM   5780  O O   . PHE A 1 773 ? 138.709 125.998 155.598 1.00 118.37 ? 793 PHE A O   1 
ATOM   5781  C CB  . PHE A 1 773 ? 138.945 125.571 158.509 1.00 113.88 ? 793 PHE A CB  1 
ATOM   5782  C CG  . PHE A 1 773 ? 140.056 125.384 159.512 1.00 115.73 ? 793 PHE A CG  1 
ATOM   5783  C CD1 . PHE A 1 773 ? 141.121 126.271 159.609 1.00 116.03 ? 793 PHE A CD1 1 
ATOM   5784  C CD2 . PHE A 1 773 ? 140.023 124.306 160.384 1.00 118.48 ? 793 PHE A CD2 1 
ATOM   5785  C CE1 . PHE A 1 773 ? 142.126 126.076 160.544 1.00 118.07 ? 793 PHE A CE1 1 
ATOM   5786  C CE2 . PHE A 1 773 ? 141.029 124.111 161.318 1.00 119.88 ? 793 PHE A CE2 1 
ATOM   5787  C CZ  . PHE A 1 773 ? 142.078 124.997 161.397 1.00 120.55 ? 793 PHE A CZ  1 
ATOM   5788  N N   . GLY A 1 774 ? 137.145 127.518 156.194 1.00 126.11 ? 794 GLY A N   1 
ATOM   5789  C CA  . GLY A 1 774 ? 136.459 127.497 154.912 1.00 130.18 ? 794 GLY A CA  1 
ATOM   5790  C C   . GLY A 1 774 ? 136.123 128.899 154.407 1.00 131.04 ? 794 GLY A C   1 
ATOM   5791  O O   . GLY A 1 774 ? 135.031 129.125 153.885 1.00 133.16 ? 794 GLY A O   1 
ATOM   5792  N N   . SER A 1 775 ? 137.076 129.827 154.559 1.00 127.89 ? 795 SER A N   1 
ATOM   5793  C CA  . SER A 1 775 ? 136.911 131.196 154.098 1.00 126.47 ? 795 SER A CA  1 
ATOM   5794  C C   . SER A 1 775 ? 138.284 131.835 153.905 1.00 124.07 ? 795 SER A C   1 
ATOM   5795  O O   . SER A 1 775 ? 139.303 131.152 153.997 1.00 121.83 ? 795 SER A O   1 
ATOM   5796  C CB  . SER A 1 775 ? 136.060 131.994 155.059 1.00 127.38 ? 795 SER A CB  1 
ATOM   5797  O OG  . SER A 1 775 ? 135.801 133.298 154.560 1.00 126.72 ? 795 SER A OG  1 
ATOM   5798  N N   . ASN A 1 776 ? 138.292 133.154 153.682 1.00 123.49 ? 796 ASN A N   1 
ATOM   5799  C CA  . ASN A 1 776 ? 139.501 133.889 153.339 1.00 123.68 ? 796 ASN A CA  1 
ATOM   5800  C C   . ASN A 1 776 ? 139.631 135.148 154.197 1.00 123.77 ? 796 ASN A C   1 
ATOM   5801  O O   . ASN A 1 776 ? 140.371 136.063 153.843 1.00 124.26 ? 796 ASN A O   1 
ATOM   5802  C CB  . ASN A 1 776 ? 139.524 134.218 151.843 1.00 123.93 ? 796 ASN A CB  1 
ATOM   5803  C CG  . ASN A 1 776 ? 138.267 134.918 151.367 1.00 124.68 ? 796 ASN A CG  1 
ATOM   5804  O OD1 . ASN A 1 776 ? 137.418 135.301 152.169 1.00 125.66 ? 796 ASN A OD1 1 
ATOM   5805  N ND2 . ASN A 1 776 ? 138.135 135.090 150.063 1.00 124.63 ? 796 ASN A ND2 1 
ATOM   5806  N N   . TYR A 1 777 ? 138.912 135.191 155.327 1.00 122.99 ? 797 TYR A N   1 
ATOM   5807  C CA  . TYR A 1 777 ? 139.085 136.219 156.343 1.00 121.28 ? 797 TYR A CA  1 
ATOM   5808  C C   . TYR A 1 777 ? 140.014 135.675 157.429 1.00 112.09 ? 797 TYR A C   1 
ATOM   5809  O O   . TYR A 1 777 ? 139.611 135.530 158.576 1.00 110.77 ? 797 TYR A O   1 
ATOM   5810  C CB  . TYR A 1 777 ? 137.721 136.636 156.911 1.00 128.77 ? 797 TYR A CB  1 
ATOM   5811  C CG  . TYR A 1 777 ? 137.070 137.831 156.255 1.00 140.64 ? 797 TYR A CG  1 
ATOM   5812  C CD1 . TYR A 1 777 ? 137.124 138.020 154.884 1.00 146.54 ? 797 TYR A CD1 1 
ATOM   5813  C CD2 . TYR A 1 777 ? 136.383 138.772 157.010 1.00 147.65 ? 797 TYR A CD2 1 
ATOM   5814  C CE1 . TYR A 1 777 ? 136.527 139.116 154.280 1.00 151.62 ? 797 TYR A CE1 1 
ATOM   5815  C CE2 . TYR A 1 777 ? 135.778 139.872 156.422 1.00 150.77 ? 797 TYR A CE2 1 
ATOM   5816  C CZ  . TYR A 1 777 ? 135.849 140.046 155.051 1.00 152.32 ? 797 TYR A CZ  1 
ATOM   5817  O OH  . TYR A 1 777 ? 135.250 141.134 154.462 1.00 149.92 ? 797 TYR A OH  1 
ATOM   5818  N N   . LYS A 1 778 ? 141.259 135.370 157.052 1.00 103.14 ? 798 LYS A N   1 
ATOM   5819  C CA  . LYS A 1 778 ? 142.210 134.712 157.939 1.00 96.71  ? 798 LYS A CA  1 
ATOM   5820  C C   . LYS A 1 778 ? 142.620 135.657 159.069 1.00 89.62  ? 798 LYS A C   1 
ATOM   5821  O O   . LYS A 1 778 ? 142.390 135.382 160.248 1.00 89.12  ? 798 LYS A O   1 
ATOM   5822  C CB  . LYS A 1 778 ? 143.465 134.278 157.172 1.00 99.05  ? 798 LYS A CB  1 
ATOM   5823  C CG  . LYS A 1 778 ? 143.623 132.790 156.901 1.00 99.87  ? 798 LYS A CG  1 
ATOM   5824  C CD  . LYS A 1 778 ? 142.469 132.157 156.157 1.00 102.08 ? 798 LYS A CD  1 
ATOM   5825  C CE  . LYS A 1 778 ? 142.901 130.925 155.387 1.00 104.88 ? 798 LYS A CE  1 
ATOM   5826  N NZ  . LYS A 1 778 ? 141.848 130.431 154.468 1.00 106.17 ? 798 LYS A NZ  1 
ATOM   5827  N N   . ALA A 1 779 ? 143.229 136.783 158.683 1.00 82.85  ? 799 ALA A N   1 
ATOM   5828  C CA  . ALA A 1 779 ? 143.955 137.630 159.611 1.00 78.60  ? 799 ALA A CA  1 
ATOM   5829  C C   . ALA A 1 779 ? 143.006 138.273 160.618 1.00 73.44  ? 799 ALA A C   1 
ATOM   5830  O O   . ALA A 1 779 ? 143.321 138.344 161.803 1.00 74.21  ? 799 ALA A O   1 
ATOM   5831  C CB  . ALA A 1 779 ? 144.732 138.672 158.846 1.00 80.59  ? 799 ALA A CB  1 
ATOM   5832  N N   . ILE A 1 780 ? 141.856 138.755 160.139 1.00 68.24  ? 800 ILE A N   1 
ATOM   5833  C CA  . ILE A 1 780 ? 140.945 139.510 160.983 1.00 65.45  ? 800 ILE A CA  1 
ATOM   5834  C C   . ILE A 1 780 ? 140.410 138.620 162.103 1.00 62.80  ? 800 ILE A C   1 
ATOM   5835  O O   . ILE A 1 780 ? 140.375 139.032 163.265 1.00 64.25  ? 800 ILE A O   1 
ATOM   5836  C CB  . ILE A 1 780 ? 139.810 140.156 160.162 1.00 66.82  ? 800 ILE A CB  1 
ATOM   5837  C CG1 . ILE A 1 780 ? 138.877 140.962 161.067 1.00 68.62  ? 800 ILE A CG1 1 
ATOM   5838  C CG2 . ILE A 1 780 ? 139.044 139.140 159.322 1.00 67.65  ? 800 ILE A CG2 1 
ATOM   5839  C CD1 . ILE A 1 780 ? 139.511 142.217 161.632 1.00 69.65  ? 800 ILE A CD1 1 
ATOM   5840  N N   . THR A 1 781 ? 139.998 137.400 161.750 1.00 59.89  ? 801 THR A N   1 
ATOM   5841  C CA  . THR A 1 781 ? 139.403 136.513 162.736 1.00 58.55  ? 801 THR A CA  1 
ATOM   5842  C C   . THR A 1 781 ? 140.490 136.008 163.676 1.00 56.09  ? 801 THR A C   1 
ATOM   5843  O O   . THR A 1 781 ? 140.208 135.770 164.844 1.00 55.48  ? 801 THR A O   1 
ATOM   5844  C CB  . THR A 1 781 ? 138.587 135.369 162.119 1.00 60.28  ? 801 THR A CB  1 
ATOM   5845  O OG1 . THR A 1 781 ? 139.460 134.303 161.747 1.00 59.48  ? 801 THR A OG1 1 
ATOM   5846  C CG2 . THR A 1 781 ? 137.738 135.811 160.946 1.00 62.02  ? 801 THR A CG2 1 
ATOM   5847  N N   . MET A 1 782 ? 141.725 135.857 163.185 1.00 55.37  ? 802 MET A N   1 
ATOM   5848  C CA  . MET A 1 782 ? 142.829 135.480 164.055 1.00 55.18  ? 802 MET A CA  1 
ATOM   5849  C C   . MET A 1 782 ? 143.068 136.591 165.078 1.00 55.80  ? 802 MET A C   1 
ATOM   5850  O O   . MET A 1 782 ? 143.292 136.311 166.252 1.00 56.60  ? 802 MET A O   1 
ATOM   5851  C CB  . MET A 1 782 ? 144.124 135.220 163.273 1.00 55.14  ? 802 MET A CB  1 
ATOM   5852  C CG  . MET A 1 782 ? 144.476 133.753 163.096 1.00 54.66  ? 802 MET A CG  1 
ATOM   5853  S SD  . MET A 1 782 ? 144.513 132.799 164.625 1.00 53.37  ? 802 MET A SD  1 
ATOM   5854  C CE  . MET A 1 782 ? 145.519 133.876 165.640 1.00 53.77  ? 802 MET A CE  1 
ATOM   5855  N N   . CYS A 1 783 ? 143.010 137.849 164.626 1.00 58.16  ? 803 CYS A N   1 
ATOM   5856  C CA  . CYS A 1 783 ? 143.158 138.991 165.515 1.00 61.02  ? 803 CYS A CA  1 
ATOM   5857  C C   . CYS A 1 783 ? 142.115 138.935 166.629 1.00 63.17  ? 803 CYS A C   1 
ATOM   5858  O O   . CYS A 1 783 ? 142.449 139.041 167.811 1.00 63.95  ? 803 CYS A O   1 
ATOM   5859  C CB  . CYS A 1 783 ? 143.019 140.311 164.769 1.00 61.59  ? 803 CYS A CB  1 
ATOM   5860  S SG  . CYS A 1 783 ? 144.348 140.609 163.577 1.00 63.99  ? 803 CYS A SG  1 
ATOM   5861  N N   . PHE A 1 784 ? 140.846 138.773 166.236 1.00 64.19  ? 804 PHE A N   1 
ATOM   5862  C CA  . PHE A 1 784 ? 139.756 138.703 167.193 1.00 64.53  ? 804 PHE A CA  1 
ATOM   5863  C C   . PHE A 1 784 ? 139.960 137.538 168.157 1.00 61.45  ? 804 PHE A C   1 
ATOM   5864  O O   . PHE A 1 784 ? 139.756 137.695 169.356 1.00 62.96  ? 804 PHE A O   1 
ATOM   5865  C CB  . PHE A 1 784 ? 138.414 138.587 166.468 1.00 68.21  ? 804 PHE A CB  1 
ATOM   5866  C CG  . PHE A 1 784 ? 137.790 139.908 166.104 1.00 71.40  ? 804 PHE A CG  1 
ATOM   5867  C CD1 . PHE A 1 784 ? 138.538 140.919 165.522 1.00 72.92  ? 804 PHE A CD1 1 
ATOM   5868  C CD2 . PHE A 1 784 ? 136.446 140.142 166.360 1.00 74.47  ? 804 PHE A CD2 1 
ATOM   5869  C CE1 . PHE A 1 784 ? 137.952 142.136 165.204 1.00 75.93  ? 804 PHE A CE1 1 
ATOM   5870  C CE2 . PHE A 1 784 ? 135.862 141.356 166.036 1.00 76.66  ? 804 PHE A CE2 1 
ATOM   5871  C CZ  . PHE A 1 784 ? 136.616 142.350 165.456 1.00 77.40  ? 804 PHE A CZ  1 
ATOM   5872  N N   . SER A 1 785 ? 140.352 136.377 167.624 1.00 58.34  ? 805 SER A N   1 
ATOM   5873  C CA  . SER A 1 785 ? 140.493 135.176 168.428 1.00 57.65  ? 805 SER A CA  1 
ATOM   5874  C C   . SER A 1 785 ? 141.547 135.379 169.511 1.00 58.10  ? 805 SER A C   1 
ATOM   5875  O O   . SER A 1 785 ? 141.302 135.058 170.670 1.00 58.85  ? 805 SER A O   1 
ATOM   5876  C CB  . SER A 1 785 ? 140.824 133.981 167.575 1.00 57.78  ? 805 SER A CB  1 
ATOM   5877  O OG  . SER A 1 785 ? 140.988 132.819 168.377 1.00 56.99  ? 805 SER A OG  1 
ATOM   5878  N N   . VAL A 1 786 ? 142.716 135.906 169.127 1.00 58.32  ? 806 VAL A N   1 
ATOM   5879  C CA  . VAL A 1 786 ? 143.815 136.062 170.064 1.00 58.57  ? 806 VAL A CA  1 
ATOM   5880  C C   . VAL A 1 786 ? 143.470 137.141 171.083 1.00 59.27  ? 806 VAL A C   1 
ATOM   5881  O O   . VAL A 1 786 ? 143.779 136.985 172.263 1.00 60.18  ? 806 VAL A O   1 
ATOM   5882  C CB  . VAL A 1 786 ? 145.145 136.364 169.351 1.00 58.68  ? 806 VAL A CB  1 
ATOM   5883  C CG1 . VAL A 1 786 ? 146.155 137.020 170.276 1.00 59.90  ? 806 VAL A CG1 1 
ATOM   5884  C CG2 . VAL A 1 786 ? 145.734 135.114 168.734 1.00 58.24  ? 806 VAL A CG2 1 
ATOM   5885  N N   . SER A 1 787 ? 142.837 138.226 170.624 1.00 60.64  ? 807 SER A N   1 
ATOM   5886  C CA  . SER A 1 787 ? 142.457 139.303 171.524 1.00 62.80  ? 807 SER A CA  1 
ATOM   5887  C C   . SER A 1 787 ? 141.505 138.787 172.604 1.00 62.93  ? 807 SER A C   1 
ATOM   5888  O O   . SER A 1 787 ? 141.654 139.102 173.783 1.00 62.36  ? 807 SER A O   1 
ATOM   5889  C CB  . SER A 1 787 ? 141.863 140.466 170.778 1.00 64.74  ? 807 SER A CB  1 
ATOM   5890  O OG  . SER A 1 787 ? 141.545 141.512 171.687 1.00 66.50  ? 807 SER A OG  1 
ATOM   5891  N N   . LEU A 1 788 ? 140.532 137.966 172.200 1.00 63.76  ? 808 LEU A N   1 
ATOM   5892  C CA  . LEU A 1 788 ? 139.561 137.405 173.128 1.00 65.03  ? 808 LEU A CA  1 
ATOM   5893  C C   . LEU A 1 788 ? 140.252 136.447 174.098 1.00 65.14  ? 808 LEU A C   1 
ATOM   5894  O O   . LEU A 1 788 ? 139.965 136.458 175.287 1.00 67.42  ? 808 LEU A O   1 
ATOM   5895  C CB  . LEU A 1 788 ? 138.471 136.675 172.332 1.00 67.32  ? 808 LEU A CB  1 
ATOM   5896  C CG  . LEU A 1 788 ? 137.190 137.455 172.031 1.00 70.94  ? 808 LEU A CG  1 
ATOM   5897  C CD1 . LEU A 1 788 ? 137.451 138.723 171.231 1.00 71.89  ? 808 LEU A CD1 1 
ATOM   5898  C CD2 . LEU A 1 788 ? 136.207 136.568 171.281 1.00 72.53  ? 808 LEU A CD2 1 
ATOM   5899  N N   . SER A 1 789 ? 141.153 135.610 173.572 1.00 63.44  ? 809 SER A N   1 
ATOM   5900  C CA  . SER A 1 789 ? 141.735 134.528 174.346 1.00 62.65  ? 809 SER A CA  1 
ATOM   5901  C C   . SER A 1 789 ? 142.709 135.068 175.388 1.00 62.34  ? 809 SER A C   1 
ATOM   5902  O O   . SER A 1 789 ? 143.060 134.348 176.319 1.00 61.99  ? 809 SER A O   1 
ATOM   5903  C CB  . SER A 1 789 ? 142.403 133.526 173.446 1.00 63.24  ? 809 SER A CB  1 
ATOM   5904  O OG  . SER A 1 789 ? 141.455 132.897 172.596 1.00 63.92  ? 809 SER A OG  1 
ATOM   5905  N N   . ALA A 1 790 ? 143.175 136.310 175.203 1.00 65.08  ? 810 ALA A N   1 
ATOM   5906  C CA  . ALA A 1 790 ? 144.118 136.924 176.127 1.00 67.84  ? 810 ALA A CA  1 
ATOM   5907  C C   . ALA A 1 790 ? 143.374 137.765 177.162 1.00 69.59  ? 810 ALA A C   1 
ATOM   5908  O O   . ALA A 1 790 ? 143.684 137.708 178.352 1.00 71.16  ? 810 ALA A O   1 
ATOM   5909  C CB  . ALA A 1 790 ? 145.139 137.737 175.369 1.00 68.45  ? 810 ALA A CB  1 
ATOM   5910  N N   . THR A 1 791 ? 142.393 138.550 176.704 1.00 70.20  ? 811 THR A N   1 
ATOM   5911  C CA  . THR A 1 791 ? 141.549 139.317 177.608 1.00 71.42  ? 811 THR A CA  1 
ATOM   5912  C C   . THR A 1 791 ? 141.018 138.400 178.710 1.00 70.66  ? 811 THR A C   1 
ATOM   5913  O O   . THR A 1 791 ? 141.014 138.771 179.883 1.00 70.81  ? 811 THR A O   1 
ATOM   5914  C CB  . THR A 1 791 ? 140.398 140.004 176.862 1.00 73.71  ? 811 THR A CB  1 
ATOM   5915  O OG1 . THR A 1 791 ? 140.955 140.782 175.802 1.00 74.79  ? 811 THR A OG1 1 
ATOM   5916  C CG2 . THR A 1 791 ? 139.558 140.891 177.757 1.00 75.02  ? 811 THR A CG2 1 
ATOM   5917  N N   . VAL A 1 792 ? 140.604 137.187 178.315 1.00 69.91  ? 812 VAL A N   1 
ATOM   5918  C CA  . VAL A 1 792 ? 140.072 136.210 179.247 1.00 70.35  ? 812 VAL A CA  1 
ATOM   5919  C C   . VAL A 1 792 ? 141.094 135.977 180.354 1.00 71.62  ? 812 VAL A C   1 
ATOM   5920  O O   . VAL A 1 792 ? 140.803 136.259 181.513 1.00 72.21  ? 812 VAL A O   1 
ATOM   5921  C CB  . VAL A 1 792 ? 139.677 134.902 178.535 1.00 71.18  ? 812 VAL A CB  1 
ATOM   5922  C CG1 . VAL A 1 792 ? 139.536 133.730 179.494 1.00 71.92  ? 812 VAL A CG1 1 
ATOM   5923  C CG2 . VAL A 1 792 ? 138.406 135.079 177.720 1.00 71.79  ? 812 VAL A CG2 1 
ATOM   5924  N N   . LEU A 1 793 ? 142.296 135.517 179.985 1.00 73.81  ? 813 LEU A N   1 
ATOM   5925  C CA  . LEU A 1 793 ? 143.320 135.197 180.971 1.00 76.10  ? 813 LEU A CA  1 
ATOM   5926  C C   . LEU A 1 793 ? 143.621 136.446 181.798 1.00 79.46  ? 813 LEU A C   1 
ATOM   5927  O O   . LEU A 1 793 ? 143.490 136.431 183.019 1.00 81.59  ? 813 LEU A O   1 
ATOM   5928  C CB  . LEU A 1 793 ? 144.575 134.670 180.266 1.00 76.32  ? 813 LEU A CB  1 
ATOM   5929  C CG  . LEU A 1 793 ? 145.456 133.740 181.102 1.00 77.67  ? 813 LEU A CG  1 
ATOM   5930  C CD1 . LEU A 1 793 ? 146.499 133.047 180.238 1.00 78.21  ? 813 LEU A CD1 1 
ATOM   5931  C CD2 . LEU A 1 793 ? 146.136 134.488 182.240 1.00 78.42  ? 813 LEU A CD2 1 
ATOM   5932  N N   . LEU A 1 794 ? 143.969 137.542 181.113 1.00 81.46  ? 814 LEU A N   1 
ATOM   5933  C CA  . LEU A 1 794 ? 144.312 138.780 181.793 1.00 83.41  ? 814 LEU A CA  1 
ATOM   5934  C C   . LEU A 1 794 ? 143.148 139.240 182.675 1.00 87.04  ? 814 LEU A C   1 
ATOM   5935  O O   . LEU A 1 794 ? 143.356 140.021 183.599 1.00 88.09  ? 814 LEU A O   1 
ATOM   5936  C CB  . LEU A 1 794 ? 144.684 139.849 180.761 1.00 83.66  ? 814 LEU A CB  1 
ATOM   5937  C CG  . LEU A 1 794 ? 145.353 141.101 181.333 1.00 85.42  ? 814 LEU A CG  1 
ATOM   5938  C CD1 . LEU A 1 794 ? 146.817 140.843 181.672 1.00 85.43  ? 814 LEU A CD1 1 
ATOM   5939  C CD2 . LEU A 1 794 ? 145.235 142.275 180.372 1.00 87.38  ? 814 LEU A CD2 1 
ATOM   5940  N N   . GLY A 1 795 ? 141.930 138.758 182.386 1.00 92.03  ? 815 GLY A N   1 
ATOM   5941  C CA  . GLY A 1 795 ? 140.744 139.119 183.149 1.00 97.82  ? 815 GLY A CA  1 
ATOM   5942  C C   . GLY A 1 795 ? 140.393 138.104 184.236 1.00 102.99 ? 815 GLY A C   1 
ATOM   5943  O O   . GLY A 1 795 ? 140.429 138.409 185.429 1.00 104.39 ? 815 GLY A O   1 
ATOM   5944  N N   . CYS A 1 796 ? 140.023 136.889 183.816 1.00 108.32 ? 816 CYS A N   1 
ATOM   5945  C CA  . CYS A 1 796 ? 139.651 135.834 184.747 1.00 113.17 ? 816 CYS A CA  1 
ATOM   5946  C C   . CYS A 1 796 ? 140.853 135.390 185.585 1.00 112.28 ? 816 CYS A C   1 
ATOM   5947  O O   . CYS A 1 796 ? 140.779 134.390 186.299 1.00 114.92 ? 816 CYS A O   1 
ATOM   5948  C CB  . CYS A 1 796 ? 139.072 134.644 183.996 1.00 118.18 ? 816 CYS A CB  1 
ATOM   5949  S SG  . CYS A 1 796 ? 137.544 135.021 183.098 1.00 127.73 ? 816 CYS A SG  1 
ATOM   5950  N N   . MET A 1 797 ? 141.965 136.123 185.449 1.00 110.10 ? 817 MET A N   1 
ATOM   5951  C CA  . MET A 1 797 ? 143.089 136.060 186.364 1.00 109.39 ? 817 MET A CA  1 
ATOM   5952  C C   . MET A 1 797 ? 143.536 137.498 186.604 1.00 112.54 ? 817 MET A C   1 
ATOM   5953  O O   . MET A 1 797 ? 143.090 138.397 185.896 1.00 111.96 ? 817 MET A O   1 
ATOM   5954  C CB  . MET A 1 797 ? 144.228 135.248 185.745 1.00 107.14 ? 817 MET A CB  1 
ATOM   5955  C CG  . MET A 1 797 ? 145.346 134.926 186.694 1.00 106.99 ? 817 MET A CG  1 
ATOM   5956  S SD  . MET A 1 797 ? 146.552 133.846 185.904 1.00 108.86 ? 817 MET A SD  1 
ATOM   5957  C CE  . MET A 1 797 ? 146.958 132.756 187.268 1.00 112.33 ? 817 MET A CE  1 
ATOM   5958  N N   . PHE A 1 798 ? 144.334 137.725 187.652 1.00 119.10 ? 818 PHE A N   1 
ATOM   5959  C CA  . PHE A 1 798 ? 144.959 139.019 187.904 1.00 126.25 ? 818 PHE A CA  1 
ATOM   5960  C C   . PHE A 1 798 ? 143.933 140.097 188.259 1.00 129.22 ? 818 PHE A C   1 
ATOM   5961  O O   . PHE A 1 798 ? 144.125 140.811 189.238 1.00 130.12 ? 818 PHE A O   1 
ATOM   5962  C CB  . PHE A 1 798 ? 145.815 139.478 186.719 1.00 128.28 ? 818 PHE A CB  1 
ATOM   5963  C CG  . PHE A 1 798 ? 146.914 138.523 186.334 1.00 130.78 ? 818 PHE A CG  1 
ATOM   5964  C CD1 . PHE A 1 798 ? 147.878 138.137 187.254 1.00 133.21 ? 818 PHE A CD1 1 
ATOM   5965  C CD2 . PHE A 1 798 ? 146.966 137.990 185.057 1.00 131.91 ? 818 PHE A CD2 1 
ATOM   5966  C CE1 . PHE A 1 798 ? 148.883 137.252 186.895 1.00 134.18 ? 818 PHE A CE1 1 
ATOM   5967  C CE2 . PHE A 1 798 ? 147.968 137.100 184.702 1.00 133.18 ? 818 PHE A CE2 1 
ATOM   5968  C CZ  . PHE A 1 798 ? 148.926 136.734 185.620 1.00 133.25 ? 818 PHE A CZ  1 
ATOM   5969  N N   . VAL A 1 799 ? 142.877 140.247 187.444 1.00 130.36 ? 819 VAL A N   1 
ATOM   5970  C CA  . VAL A 1 799 ? 141.899 141.308 187.647 1.00 132.15 ? 819 VAL A CA  1 
ATOM   5971  C C   . VAL A 1 799 ? 141.285 141.177 189.043 1.00 136.58 ? 819 VAL A C   1 
ATOM   5972  O O   . VAL A 1 799 ? 141.109 142.182 189.728 1.00 137.86 ? 819 VAL A O   1 
ATOM   5973  C CB  . VAL A 1 799 ? 140.834 141.336 186.531 1.00 131.54 ? 819 VAL A CB  1 
ATOM   5974  C CG1 . VAL A 1 799 ? 139.560 142.050 186.960 1.00 131.24 ? 819 VAL A CG1 1 
ATOM   5975  C CG2 . VAL A 1 799 ? 141.387 141.956 185.260 1.00 131.83 ? 819 VAL A CG2 1 
ATOM   5976  N N   . PRO A 1 800 ? 140.929 139.958 189.511 1.00 141.46 ? 820 PRO A N   1 
ATOM   5977  C CA  . PRO A 1 800 ? 140.689 139.735 190.935 1.00 143.06 ? 820 PRO A CA  1 
ATOM   5978  C C   . PRO A 1 800 ? 141.813 140.310 191.793 1.00 141.81 ? 820 PRO A C   1 
ATOM   5979  O O   . PRO A 1 800 ? 141.582 141.198 192.604 1.00 142.78 ? 820 PRO A O   1 
ATOM   5980  C CB  . PRO A 1 800 ? 140.592 138.205 191.069 1.00 143.29 ? 820 PRO A CB  1 
ATOM   5981  C CG  . PRO A 1 800 ? 140.998 137.657 189.710 1.00 142.62 ? 820 PRO A CG  1 
ATOM   5982  C CD  . PRO A 1 800 ? 140.644 138.750 188.721 1.00 142.27 ? 820 PRO A CD  1 
ATOM   5983  N N   . LYS A 1 801 ? 143.038 139.817 191.576 1.00 140.74 ? 821 LYS A N   1 
ATOM   5984  C CA  . LYS A 1 801 ? 144.185 140.173 192.401 1.00 142.08 ? 821 LYS A CA  1 
ATOM   5985  C C   . LYS A 1 801 ? 144.320 141.694 192.468 1.00 144.08 ? 821 LYS A C   1 
ATOM   5986  O O   . LYS A 1 801 ? 144.461 142.251 193.553 1.00 145.53 ? 821 LYS A O   1 
ATOM   5987  C CB  . LYS A 1 801 ? 145.476 139.547 191.856 1.00 143.37 ? 821 LYS A CB  1 
ATOM   5988  C CG  . LYS A 1 801 ? 145.458 138.037 191.648 1.00 144.44 ? 821 LYS A CG  1 
ATOM   5989  C CD  . LYS A 1 801 ? 146.687 137.517 190.936 1.00 146.05 ? 821 LYS A CD  1 
ATOM   5990  C CE  . LYS A 1 801 ? 146.568 136.059 190.549 1.00 147.66 ? 821 LYS A CE  1 
ATOM   5991  N NZ  . LYS A 1 801 ? 147.794 135.572 189.873 1.00 148.54 ? 821 LYS A NZ  1 
ATOM   5992  N N   . VAL A 1 802 ? 144.169 142.371 191.319 1.00 147.50 ? 822 VAL A N   1 
ATOM   5993  C CA  . VAL A 1 802 ? 144.255 143.824 191.248 1.00 151.74 ? 822 VAL A CA  1 
ATOM   5994  C C   . VAL A 1 802 ? 143.227 144.444 192.197 1.00 157.89 ? 822 VAL A C   1 
ATOM   5995  O O   . VAL A 1 802 ? 143.529 145.415 192.884 1.00 158.39 ? 822 VAL A O   1 
ATOM   5996  C CB  . VAL A 1 802 ? 144.089 144.338 189.800 1.00 151.08 ? 822 VAL A CB  1 
ATOM   5997  C CG1 . VAL A 1 802 ? 143.578 145.774 189.729 1.00 151.11 ? 822 VAL A CG1 1 
ATOM   5998  C CG2 . VAL A 1 802 ? 145.379 144.208 188.999 1.00 150.42 ? 822 VAL A CG2 1 
ATOM   5999  N N   . TYR A 1 803 ? 142.015 143.876 192.221 1.00 164.01 ? 823 TYR A N   1 
ATOM   6000  C CA  . TYR A 1 803 ? 140.969 144.337 193.121 1.00 169.25 ? 823 TYR A CA  1 
ATOM   6001  C C   . TYR A 1 803 ? 141.458 144.259 194.567 1.00 168.99 ? 823 TYR A C   1 
ATOM   6002  O O   . TYR A 1 803 ? 141.272 145.199 195.340 1.00 168.56 ? 823 TYR A O   1 
ATOM   6003  C CB  . TYR A 1 803 ? 139.688 143.522 192.918 1.00 174.99 ? 823 TYR A CB  1 
ATOM   6004  C CG  . TYR A 1 803 ? 138.596 143.817 193.914 1.00 182.85 ? 823 TYR A CG  1 
ATOM   6005  C CD1 . TYR A 1 803 ? 138.089 145.099 194.051 1.00 186.63 ? 823 TYR A CD1 1 
ATOM   6006  C CD2 . TYR A 1 803 ? 138.098 142.830 194.749 1.00 187.83 ? 823 TYR A CD2 1 
ATOM   6007  C CE1 . TYR A 1 803 ? 137.089 145.387 194.968 1.00 190.90 ? 823 TYR A CE1 1 
ATOM   6008  C CE2 . TYR A 1 803 ? 137.100 143.100 195.672 1.00 191.70 ? 823 TYR A CE2 1 
ATOM   6009  C CZ  . TYR A 1 803 ? 136.594 144.384 195.784 1.00 193.20 ? 823 TYR A CZ  1 
ATOM   6010  O OH  . TYR A 1 803 ? 135.606 144.661 196.700 1.00 192.81 ? 823 TYR A OH  1 
ATOM   6011  N N   . ILE A 1 804 ? 142.101 143.136 194.913 1.00 169.75 ? 824 ILE A N   1 
ATOM   6012  C CA  . ILE A 1 804 ? 142.627 142.913 196.252 1.00 171.97 ? 824 ILE A CA  1 
ATOM   6013  C C   . ILE A 1 804 ? 143.692 143.968 196.553 1.00 169.81 ? 824 ILE A C   1 
ATOM   6014  O O   . ILE A 1 804 ? 143.654 144.584 197.614 1.00 170.21 ? 824 ILE A O   1 
ATOM   6015  C CB  . ILE A 1 804 ? 143.157 141.470 196.414 1.00 175.24 ? 824 ILE A CB  1 
ATOM   6016  C CG1 . ILE A 1 804 ? 142.046 140.444 196.170 1.00 176.35 ? 824 ILE A CG1 1 
ATOM   6017  C CG2 . ILE A 1 804 ? 143.818 141.261 197.776 1.00 176.01 ? 824 ILE A CG2 1 
ATOM   6018  C CD1 . ILE A 1 804 ? 142.524 139.008 196.045 1.00 176.41 ? 824 ILE A CD1 1 
ATOM   6019  N N   . ILE A 1 805 ? 144.631 144.166 195.619 1.00 167.62 ? 825 ILE A N   1 
ATOM   6020  C CA  . ILE A 1 805 ? 145.682 145.162 195.772 1.00 169.81 ? 825 ILE A CA  1 
ATOM   6021  C C   . ILE A 1 805 ? 145.065 146.525 196.093 1.00 174.54 ? 825 ILE A C   1 
ATOM   6022  O O   . ILE A 1 805 ? 145.584 147.256 196.938 1.00 176.24 ? 825 ILE A O   1 
ATOM   6023  C CB  . ILE A 1 805 ? 146.570 145.219 194.510 1.00 172.02 ? 825 ILE A CB  1 
ATOM   6024  C CG1 . ILE A 1 805 ? 147.363 143.925 194.307 1.00 173.13 ? 825 ILE A CG1 1 
ATOM   6025  C CG2 . ILE A 1 805 ? 147.491 146.427 194.552 1.00 173.52 ? 825 ILE A CG2 1 
ATOM   6026  C CD1 . ILE A 1 805 ? 148.278 143.581 195.455 1.00 173.00 ? 825 ILE A CD1 1 
ATOM   6027  N N   . LEU A 1 806 ? 143.956 146.850 195.415 1.00 179.18 ? 826 LEU A N   1 
ATOM   6028  C CA  . LEU A 1 806 ? 143.291 148.133 195.585 1.00 184.66 ? 826 LEU A CA  1 
ATOM   6029  C C   . LEU A 1 806 ? 142.741 148.200 197.008 1.00 188.10 ? 826 LEU A C   1 
ATOM   6030  O O   . LEU A 1 806 ? 143.117 149.088 197.773 1.00 189.09 ? 826 LEU A O   1 
ATOM   6031  C CB  . LEU A 1 806 ? 142.209 148.280 194.504 1.00 186.13 ? 826 LEU A CB  1 
ATOM   6032  C CG  . LEU A 1 806 ? 141.364 149.560 194.490 1.00 186.98 ? 826 LEU A CG  1 
ATOM   6033  C CD1 . LEU A 1 806 ? 140.180 149.473 195.447 1.00 186.24 ? 826 LEU A CD1 1 
ATOM   6034  C CD2 . LEU A 1 806 ? 142.201 150.799 194.792 1.00 187.00 ? 826 LEU A CD2 1 
ATOM   6035  N N   . ALA A 1 807 ? 141.954 147.184 197.382 1.00 188.86 ? 827 ALA A N   1 
ATOM   6036  C CA  . ALA A 1 807 ? 141.395 147.090 198.726 1.00 190.17 ? 827 ALA A CA  1 
ATOM   6037  C C   . ALA A 1 807 ? 142.474 147.345 199.790 1.00 188.97 ? 827 ALA A C   1 
ATOM   6038  O O   . ALA A 1 807 ? 142.149 148.021 200.787 1.00 185.59 ? 827 ALA A O   1 
ATOM   6039  C CB  . ALA A 1 807 ? 140.759 145.739 198.931 1.00 189.81 ? 827 ALA A CB  1 
ATOM   6040  N N   . ARG B 1 5   ? 145.538 121.777 50.100  1.00 132.04 ? 25  ARG B N   1 
ATOM   6041  C CA  . ARG B 1 5   ? 144.290 121.768 50.913  1.00 132.11 ? 25  ARG B CA  1 
ATOM   6042  C C   . ARG B 1 5   ? 144.165 120.416 51.618  1.00 121.52 ? 25  ARG B C   1 
ATOM   6043  O O   . ARG B 1 5   ? 144.900 119.479 51.305  1.00 121.57 ? 25  ARG B O   1 
ATOM   6044  C CB  . ARG B 1 5   ? 143.073 122.064 50.027  1.00 139.98 ? 25  ARG B CB  1 
ATOM   6045  C CG  . ARG B 1 5   ? 143.123 123.384 49.268  1.00 148.67 ? 25  ARG B CG  1 
ATOM   6046  C CD  . ARG B 1 5   ? 142.947 124.622 50.136  1.00 156.28 ? 25  ARG B CD  1 
ATOM   6047  N NE  . ARG B 1 5   ? 144.137 124.988 50.896  1.00 162.59 ? 25  ARG B NE  1 
ATOM   6048  C CZ  . ARG B 1 5   ? 145.250 125.508 50.379  1.00 167.87 ? 25  ARG B CZ  1 
ATOM   6049  N NH1 . ARG B 1 5   ? 145.334 125.773 49.086  1.00 168.69 ? 25  ARG B NH1 1 
ATOM   6050  N NH2 . ARG B 1 5   ? 146.280 125.775 51.166  1.00 168.16 ? 25  ARG B NH2 1 
ATOM   6051  N N   . ARG B 1 6   ? 143.239 120.335 52.581  1.00 108.63 ? 26  ARG B N   1 
ATOM   6052  C CA  . ARG B 1 6   ? 143.043 119.121 53.356  1.00 98.75  ? 26  ARG B CA  1 
ATOM   6053  C C   . ARG B 1 6   ? 142.352 118.054 52.510  1.00 93.36  ? 26  ARG B C   1 
ATOM   6054  O O   . ARG B 1 6   ? 141.564 118.359 51.618  1.00 92.32  ? 26  ARG B O   1 
ATOM   6055  C CB  . ARG B 1 6   ? 142.240 119.391 54.632  1.00 94.98  ? 26  ARG B CB  1 
ATOM   6056  C CG  . ARG B 1 6   ? 143.105 119.564 55.869  1.00 92.19  ? 26  ARG B CG  1 
ATOM   6057  C CD  . ARG B 1 6   ? 142.276 119.595 57.139  1.00 89.31  ? 26  ARG B CD  1 
ATOM   6058  N NE  . ARG B 1 6   ? 142.979 120.261 58.227  1.00 85.74  ? 26  ARG B NE  1 
ATOM   6059  C CZ  . ARG B 1 6   ? 143.253 121.563 58.264  1.00 83.70  ? 26  ARG B CZ  1 
ATOM   6060  N NH1 . ARG B 1 6   ? 142.893 122.352 57.266  1.00 83.25  ? 26  ARG B NH1 1 
ATOM   6061  N NH2 . ARG B 1 6   ? 143.875 122.075 59.310  1.00 83.46  ? 26  ARG B NH2 1 
ATOM   6062  N N   . VAL B 1 7   ? 142.658 116.798 52.843  1.00 87.18  ? 27  VAL B N   1 
ATOM   6063  C CA  . VAL B 1 7   ? 142.116 115.642 52.151  1.00 83.33  ? 27  VAL B CA  1 
ATOM   6064  C C   . VAL B 1 7   ? 140.772 115.279 52.775  1.00 79.30  ? 27  VAL B C   1 
ATOM   6065  O O   . VAL B 1 7   ? 140.542 115.528 53.956  1.00 79.50  ? 27  VAL B O   1 
ATOM   6066  C CB  . VAL B 1 7   ? 143.102 114.458 52.191  1.00 84.87  ? 27  VAL B CB  1 
ATOM   6067  C CG1 . VAL B 1 7   ? 144.307 114.717 51.300  1.00 86.08  ? 27  VAL B CG1 1 
ATOM   6068  C CG2 . VAL B 1 7   ? 143.548 114.112 53.607  1.00 85.02  ? 27  VAL B CG2 1 
ATOM   6069  N N   . VAL B 1 8   ? 139.896 114.678 51.963  1.00 76.07  ? 28  VAL B N   1 
ATOM   6070  C CA  . VAL B 1 8   ? 138.552 114.316 52.387  1.00 73.56  ? 28  VAL B CA  1 
ATOM   6071  C C   . VAL B 1 8   ? 138.253 112.906 51.888  1.00 73.01  ? 28  VAL B C   1 
ATOM   6072  O O   . VAL B 1 8   ? 138.602 112.568 50.764  1.00 73.69  ? 28  VAL B O   1 
ATOM   6073  C CB  . VAL B 1 8   ? 137.522 115.329 51.853  1.00 73.01  ? 28  VAL B CB  1 
ATOM   6074  C CG1 . VAL B 1 8   ? 137.704 115.602 50.366  1.00 73.54  ? 28  VAL B CG1 1 
ATOM   6075  C CG2 . VAL B 1 8   ? 136.100 114.889 52.137  1.00 72.59  ? 28  VAL B CG2 1 
ATOM   6076  N N   . ALA B 1 9   ? 137.623 112.090 52.740  1.00 72.87  ? 29  ALA B N   1 
ATOM   6077  C CA  . ALA B 1 9   ? 137.266 110.728 52.382  1.00 74.16  ? 29  ALA B CA  1 
ATOM   6078  C C   . ALA B 1 9   ? 135.911 110.734 51.683  1.00 76.26  ? 29  ALA B C   1 
ATOM   6079  O O   . ALA B 1 9   ? 135.019 111.484 52.070  1.00 74.90  ? 29  ALA B O   1 
ATOM   6080  C CB  . ALA B 1 9   ? 137.242 109.858 53.614  1.00 73.59  ? 29  ALA B CB  1 
ATOM   6081  N N   . HIS B 1 10  ? 135.768 109.855 50.685  1.00 81.74  ? 30  HIS B N   1 
ATOM   6082  C CA  . HIS B 1 10  ? 134.618 109.857 49.803  1.00 86.41  ? 30  HIS B CA  1 
ATOM   6083  C C   . HIS B 1 10  ? 133.970 108.475 49.753  1.00 85.14  ? 30  HIS B C   1 
ATOM   6084  O O   . HIS B 1 10  ? 134.630 107.452 49.915  1.00 84.72  ? 30  HIS B O   1 
ATOM   6085  C CB  . HIS B 1 10  ? 135.038 110.268 48.388  1.00 92.24  ? 30  HIS B CB  1 
ATOM   6086  C CG  . HIS B 1 10  ? 135.103 111.738 48.153  1.00 100.24 ? 30  HIS B CG  1 
ATOM   6087  N ND1 . HIS B 1 10  ? 136.240 112.374 47.705  1.00 106.15 ? 30  HIS B ND1 1 
ATOM   6088  C CD2 . HIS B 1 10  ? 134.162 112.689 48.255  1.00 105.12 ? 30  HIS B CD2 1 
ATOM   6089  C CE1 . HIS B 1 10  ? 135.992 113.671 47.573  1.00 108.98 ? 30  HIS B CE1 1 
ATOM   6090  N NE2 . HIS B 1 10  ? 134.736 113.884 47.903  1.00 107.92 ? 30  HIS B NE2 1 
ATOM   6091  N N   . MET B 1 11  ? 132.656 108.478 49.520  1.00 83.96  ? 31  MET B N   1 
ATOM   6092  C CA  . MET B 1 11  ? 131.956 107.306 49.033  1.00 83.62  ? 31  MET B CA  1 
ATOM   6093  C C   . MET B 1 11  ? 130.758 107.786 48.219  1.00 83.89  ? 31  MET B C   1 
ATOM   6094  O O   . MET B 1 11  ? 129.924 108.527 48.734  1.00 83.52  ? 31  MET B O   1 
ATOM   6095  C CB  . MET B 1 11  ? 131.490 106.418 50.188  1.00 84.03  ? 31  MET B CB  1 
ATOM   6096  C CG  . MET B 1 11  ? 130.730 105.182 49.731  1.00 85.85  ? 31  MET B CG  1 
ATOM   6097  S SD  . MET B 1 11  ? 129.987 104.238 51.083  1.00 86.24  ? 31  MET B SD  1 
ATOM   6098  C CE  . MET B 1 11  ? 131.341 104.199 52.252  1.00 84.15  ? 31  MET B CE  1 
ATOM   6099  N N   . PRO B 1 12  ? 130.634 107.393 46.931  1.00 84.78  ? 32  PRO B N   1 
ATOM   6100  C CA  . PRO B 1 12  ? 129.537 107.860 46.086  1.00 84.23  ? 32  PRO B CA  1 
ATOM   6101  C C   . PRO B 1 12  ? 128.189 107.348 46.584  1.00 82.93  ? 32  PRO B C   1 
ATOM   6102  O O   . PRO B 1 12  ? 128.110 106.289 47.203  1.00 83.41  ? 32  PRO B O   1 
ATOM   6103  C CB  . PRO B 1 12  ? 129.846 107.292 44.690  1.00 85.95  ? 32  PRO B CB  1 
ATOM   6104  C CG  . PRO B 1 12  ? 131.287 106.819 44.763  1.00 87.15  ? 32  PRO B CG  1 
ATOM   6105  C CD  . PRO B 1 12  ? 131.527 106.470 46.218  1.00 86.29  ? 32  PRO B CD  1 
ATOM   6106  N N   . GLY B 1 13  ? 127.135 108.124 46.318  1.00 81.96  ? 33  GLY B N   1 
ATOM   6107  C CA  . GLY B 1 13  ? 125.785 107.744 46.696  1.00 81.15  ? 33  GLY B CA  1 
ATOM   6108  C C   . GLY B 1 13  ? 124.756 108.752 46.192  1.00 80.49  ? 33  GLY B C   1 
ATOM   6109  O O   . GLY B 1 13  ? 125.116 109.825 45.708  1.00 81.21  ? 33  GLY B O   1 
ATOM   6110  N N   . ASP B 1 14  ? 123.475 108.392 46.320  1.00 78.28  ? 34  ASP B N   1 
ATOM   6111  C CA  . ASP B 1 14  ? 122.384 109.265 45.917  1.00 76.59  ? 34  ASP B CA  1 
ATOM   6112  C C   . ASP B 1 14  ? 122.195 110.369 46.952  1.00 70.26  ? 34  ASP B C   1 
ATOM   6113  O O   . ASP B 1 14  ? 121.957 111.520 46.599  1.00 70.09  ? 34  ASP B O   1 
ATOM   6114  C CB  . ASP B 1 14  ? 121.102 108.460 45.710  1.00 80.43  ? 34  ASP B CB  1 
ATOM   6115  C CG  . ASP B 1 14  ? 121.233 107.422 44.610  1.00 83.98  ? 34  ASP B CG  1 
ATOM   6116  O OD1 . ASP B 1 14  ? 122.316 107.363 43.982  1.00 84.85  ? 34  ASP B OD1 1 
ATOM   6117  O OD2 . ASP B 1 14  ? 120.257 106.674 44.393  1.00 84.99  ? 34  ASP B OD2 1 
ATOM   6118  N N   . ILE B 1 15  ? 122.288 109.992 48.230  1.00 64.55  ? 35  ILE B N   1 
ATOM   6119  C CA  . ILE B 1 15  ? 122.215 110.925 49.341  1.00 60.33  ? 35  ILE B CA  1 
ATOM   6120  C C   . ILE B 1 15  ? 123.564 110.907 50.053  1.00 55.99  ? 35  ILE B C   1 
ATOM   6121  O O   . ILE B 1 15  ? 124.047 109.843 50.434  1.00 57.15  ? 35  ILE B O   1 
ATOM   6122  C CB  . ILE B 1 15  ? 121.070 110.546 50.301  1.00 60.32  ? 35  ILE B CB  1 
ATOM   6123  C CG1 . ILE B 1 15  ? 119.785 110.165 49.561  1.00 61.56  ? 35  ILE B CG1 1 
ATOM   6124  C CG2 . ILE B 1 15  ? 120.841 111.661 51.305  1.00 59.73  ? 35  ILE B CG2 1 
ATOM   6125  C CD1 . ILE B 1 15  ? 118.681 109.685 50.480  1.00 62.53  ? 35  ILE B CD1 1 
ATOM   6126  N N   . ILE B 1 16  ? 124.162 112.089 50.235  1.00 50.75  ? 36  ILE B N   1 
ATOM   6127  C CA  . ILE B 1 16  ? 125.475 112.188 50.849  1.00 47.03  ? 36  ILE B CA  1 
ATOM   6128  C C   . ILE B 1 16  ? 125.330 112.738 52.266  1.00 43.29  ? 36  ILE B C   1 
ATOM   6129  O O   . ILE B 1 16  ? 124.794 113.827 52.472  1.00 44.25  ? 36  ILE B O   1 
ATOM   6130  C CB  . ILE B 1 16  ? 126.430 113.032 49.982  1.00 47.88  ? 36  ILE B CB  1 
ATOM   6131  C CG1 . ILE B 1 16  ? 126.569 112.426 48.582  1.00 48.95  ? 36  ILE B CG1 1 
ATOM   6132  C CG2 . ILE B 1 16  ? 127.778 113.197 50.669  1.00 48.00  ? 36  ILE B CG2 1 
ATOM   6133  C CD1 . ILE B 1 16  ? 127.674 113.028 47.745  1.00 50.05  ? 36  ILE B CD1 1 
ATOM   6134  N N   . ILE B 1 17  ? 125.838 111.960 53.226  1.00 39.58  ? 37  ILE B N   1 
ATOM   6135  C CA  . ILE B 1 17  ? 125.889 112.359 54.622  1.00 37.14  ? 37  ILE B CA  1 
ATOM   6136  C C   . ILE B 1 17  ? 127.327 112.746 54.949  1.00 34.71  ? 37  ILE B C   1 
ATOM   6137  O O   . ILE B 1 17  ? 128.262 112.069 54.543  1.00 35.39  ? 37  ILE B O   1 
ATOM   6138  C CB  . ILE B 1 17  ? 125.364 111.237 55.543  1.00 37.51  ? 37  ILE B CB  1 
ATOM   6139  C CG1 . ILE B 1 17  ? 125.464 111.606 57.023  1.00 37.81  ? 37  ILE B CG1 1 
ATOM   6140  C CG2 . ILE B 1 17  ? 126.071 109.920 55.267  1.00 37.86  ? 37  ILE B CG2 1 
ATOM   6141  C CD1 . ILE B 1 17  ? 124.981 110.525 57.949  1.00 38.18  ? 37  ILE B CD1 1 
ATOM   6142  N N   . GLY B 1 18  ? 127.491 113.835 55.708  1.00 32.39  ? 38  GLY B N   1 
ATOM   6143  C CA  . GLY B 1 18  ? 128.801 114.303 56.122  1.00 30.60  ? 38  GLY B CA  1 
ATOM   6144  C C   . GLY B 1 18  ? 129.200 113.728 57.477  1.00 28.80  ? 38  GLY B C   1 
ATOM   6145  O O   . GLY B 1 18  ? 128.366 113.151 58.179  1.00 29.27  ? 38  GLY B O   1 
ATOM   6146  N N   . ALA B 1 19  ? 130.477 113.892 57.829  1.00 26.69  ? 39  ALA B N   1 
ATOM   6147  C CA  . ALA B 1 19  ? 130.971 113.499 59.138  1.00 25.13  ? 39  ALA B CA  1 
ATOM   6148  C C   . ALA B 1 19  ? 132.217 114.308 59.475  1.00 23.96  ? 39  ALA B C   1 
ATOM   6149  O O   . ALA B 1 19  ? 132.959 114.710 58.583  1.00 24.31  ? 39  ALA B O   1 
ATOM   6150  C CB  . ALA B 1 19  ? 131.247 112.015 59.179  1.00 25.06  ? 39  ALA B CB  1 
ATOM   6151  N N   . LEU B 1 20  ? 132.415 114.554 60.773  1.00 22.95  ? 40  LEU B N   1 
ATOM   6152  C CA  . LEU B 1 20  ? 133.583 115.260 61.268  1.00 22.50  ? 40  LEU B CA  1 
ATOM   6153  C C   . LEU B 1 20  ? 134.226 114.415 62.362  1.00 22.56  ? 40  LEU B C   1 
ATOM   6154  O O   . LEU B 1 20  ? 133.708 114.330 63.472  1.00 22.72  ? 40  LEU B O   1 
ATOM   6155  C CB  . LEU B 1 20  ? 133.166 116.632 61.810  1.00 22.36  ? 40  LEU B CB  1 
ATOM   6156  C CG  . LEU B 1 20  ? 132.993 117.745 60.776  1.00 22.35  ? 40  LEU B CG  1 
ATOM   6157  C CD1 . LEU B 1 20  ? 132.380 118.980 61.417  1.00 22.36  ? 40  LEU B CD1 1 
ATOM   6158  C CD2 . LEU B 1 20  ? 134.318 118.104 60.118  1.00 22.37  ? 40  LEU B CD2 1 
ATOM   6159  N N   . PHE B 1 21  ? 135.360 113.794 62.027  1.00 22.46  ? 41  PHE B N   1 
ATOM   6160  C CA  . PHE B 1 21  ? 136.108 112.988 62.974  1.00 22.35  ? 41  PHE B CA  1 
ATOM   6161  C C   . PHE B 1 21  ? 137.468 113.631 63.217  1.00 23.22  ? 41  PHE B C   1 
ATOM   6162  O O   . PHE B 1 21  ? 138.087 114.144 62.285  1.00 23.64  ? 41  PHE B O   1 
ATOM   6163  C CB  . PHE B 1 21  ? 136.258 111.563 62.440  1.00 21.68  ? 41  PHE B CB  1 
ATOM   6164  C CG  . PHE B 1 21  ? 134.953 110.837 62.252  1.00 21.17  ? 41  PHE B CG  1 
ATOM   6165  C CD1 . PHE B 1 21  ? 134.092 110.655 63.322  1.00 20.98  ? 41  PHE B CD1 1 
ATOM   6166  C CD2 . PHE B 1 21  ? 134.585 110.334 61.015  1.00 21.12  ? 41  PHE B CD2 1 
ATOM   6167  C CE1 . PHE B 1 21  ? 132.890 109.987 63.163  1.00 20.86  ? 41  PHE B CE1 1 
ATOM   6168  C CE2 . PHE B 1 21  ? 133.377 109.670 60.857  1.00 21.15  ? 41  PHE B CE2 1 
ATOM   6169  C CZ  . PHE B 1 21  ? 132.536 109.493 61.931  1.00 21.01  ? 41  PHE B CZ  1 
ATOM   6170  N N   . SER B 1 22  ? 137.921 113.596 64.475  1.00 23.97  ? 42  SER B N   1 
ATOM   6171  C CA  . SER B 1 22  ? 139.228 114.118 64.832  1.00 24.47  ? 42  SER B CA  1 
ATOM   6172  C C   . SER B 1 22  ? 140.294 113.106 64.437  1.00 24.84  ? 42  SER B C   1 
ATOM   6173  O O   . SER B 1 22  ? 140.804 112.376 65.280  1.00 25.46  ? 42  SER B O   1 
ATOM   6174  C CB  . SER B 1 22  ? 139.312 114.445 66.294  1.00 24.65  ? 42  SER B CB  1 
ATOM   6175  O OG  . SER B 1 22  ? 139.201 113.273 67.092  1.00 24.89  ? 42  SER B OG  1 
ATOM   6176  N N   . VAL B 1 23  ? 140.626 113.082 63.149  1.00 25.39  ? 43  VAL B N   1 
ATOM   6177  C CA  . VAL B 1 23  ? 141.591 112.128 62.638  1.00 26.19  ? 43  VAL B CA  1 
ATOM   6178  C C   . VAL B 1 23  ? 142.975 112.477 63.178  1.00 27.77  ? 43  VAL B C   1 
ATOM   6179  O O   . VAL B 1 23  ? 143.746 111.588 63.520  1.00 28.08  ? 43  VAL B O   1 
ATOM   6180  C CB  . VAL B 1 23  ? 141.580 112.081 61.102  1.00 26.29  ? 43  VAL B CB  1 
ATOM   6181  C CG1 . VAL B 1 23  ? 142.471 110.967 60.589  1.00 26.55  ? 43  VAL B CG1 1 
ATOM   6182  C CG2 . VAL B 1 23  ? 140.171 111.922 60.551  1.00 26.34  ? 43  VAL B CG2 1 
ATOM   6183  N N   . HIS B 1 24  ? 143.277 113.779 63.249  1.00 29.74  ? 44  HIS B N   1 
ATOM   6184  C CA  . HIS B 1 24  ? 144.561 114.268 63.723  1.00 31.23  ? 44  HIS B CA  1 
ATOM   6185  C C   . HIS B 1 24  ? 144.397 114.900 65.101  1.00 32.57  ? 44  HIS B C   1 
ATOM   6186  O O   . HIS B 1 24  ? 143.284 115.159 65.547  1.00 33.04  ? 44  HIS B O   1 
ATOM   6187  C CB  . HIS B 1 24  ? 145.136 115.274 62.723  1.00 31.66  ? 44  HIS B CB  1 
ATOM   6188  C CG  . HIS B 1 24  ? 145.529 114.662 61.424  1.00 32.58  ? 44  HIS B CG  1 
ATOM   6189  N ND1 . HIS B 1 24  ? 145.771 113.317 61.258  1.00 33.18  ? 44  HIS B ND1 1 
ATOM   6190  C CD2 . HIS B 1 24  ? 145.765 115.231 60.236  1.00 33.23  ? 44  HIS B CD2 1 
ATOM   6191  C CE1 . HIS B 1 24  ? 146.114 113.088 59.999  1.00 33.65  ? 44  HIS B CE1 1 
ATOM   6192  N NE2 . HIS B 1 24  ? 146.117 114.237 59.361  1.00 33.54  ? 44  HIS B NE2 1 
ATOM   6193  N N   . HIS B 1 25  ? 145.525 115.153 65.767  1.00 35.13  ? 45  HIS B N   1 
ATOM   6194  C CA  . HIS B 1 25  ? 145.508 115.777 67.080  1.00 37.72  ? 45  HIS B CA  1 
ATOM   6195  C C   . HIS B 1 25  ? 145.223 117.267 66.938  1.00 38.38  ? 45  HIS B C   1 
ATOM   6196  O O   . HIS B 1 25  ? 145.216 117.819 65.840  1.00 38.19  ? 45  HIS B O   1 
ATOM   6197  C CB  . HIS B 1 25  ? 146.817 115.520 67.838  1.00 40.28  ? 45  HIS B CB  1 
ATOM   6198  C CG  . HIS B 1 25  ? 146.787 114.287 68.674  1.00 42.62  ? 45  HIS B CG  1 
ATOM   6199  N ND1 . HIS B 1 25  ? 146.234 114.236 69.937  1.00 44.03  ? 45  HIS B ND1 1 
ATOM   6200  C CD2 . HIS B 1 25  ? 147.261 113.058 68.423  1.00 43.17  ? 45  HIS B CD2 1 
ATOM   6201  C CE1 . HIS B 1 25  ? 146.363 113.006 70.418  1.00 44.40  ? 45  HIS B CE1 1 
ATOM   6202  N NE2 . HIS B 1 25  ? 146.984 112.274 69.515  1.00 43.91  ? 45  HIS B NE2 1 
ATOM   6203  N N   . GLN B 1 26  ? 144.976 117.904 68.081  1.00 40.03  ? 46  GLN B N   1 
ATOM   6204  C CA  . GLN B 1 26  ? 144.728 119.332 68.125  1.00 41.57  ? 46  GLN B CA  1 
ATOM   6205  C C   . GLN B 1 26  ? 146.007 120.062 67.730  1.00 44.99  ? 46  GLN B C   1 
ATOM   6206  O O   . GLN B 1 26  ? 147.099 119.632 68.095  1.00 45.83  ? 46  GLN B O   1 
ATOM   6207  C CB  . GLN B 1 26  ? 144.264 119.708 69.530  1.00 41.27  ? 46  GLN B CB  1 
ATOM   6208  C CG  . GLN B 1 26  ? 143.735 121.124 69.656  1.00 41.31  ? 46  GLN B CG  1 
ATOM   6209  C CD  . GLN B 1 26  ? 143.150 121.346 71.029  1.00 42.07  ? 46  GLN B CD  1 
ATOM   6210  O OE1 . GLN B 1 26  ? 143.206 120.475 71.894  1.00 41.72  ? 46  GLN B OE1 1 
ATOM   6211  N NE2 . GLN B 1 26  ? 142.581 122.521 71.245  1.00 42.94  ? 46  GLN B NE2 1 
ATOM   6212  N N   . PRO B 1 27  ? 145.922 121.165 66.950  1.00 49.28  ? 47  PRO B N   1 
ATOM   6213  C CA  . PRO B 1 27  ? 147.097 121.979 66.638  1.00 52.21  ? 47  PRO B CA  1 
ATOM   6214  C C   . PRO B 1 27  ? 147.792 122.484 67.901  1.00 57.89  ? 47  PRO B C   1 
ATOM   6215  O O   . PRO B 1 27  ? 147.136 122.805 68.893  1.00 58.47  ? 47  PRO B O   1 
ATOM   6216  C CB  . PRO B 1 27  ? 146.526 123.154 65.831  1.00 50.72  ? 47  PRO B CB  1 
ATOM   6217  C CG  . PRO B 1 27  ? 145.244 122.608 65.240  1.00 50.18  ? 47  PRO B CG  1 
ATOM   6218  C CD  . PRO B 1 27  ? 144.704 121.666 66.296  1.00 49.83  ? 47  PRO B CD  1 
ATOM   6219  N N   . THR B 1 28  ? 149.125 122.562 67.847  1.00 63.79  ? 48  THR B N   1 
ATOM   6220  C CA  . THR B 1 28  ? 149.909 123.023 68.982  1.00 68.94  ? 48  THR B CA  1 
ATOM   6221  C C   . THR B 1 28  ? 149.672 124.519 69.173  1.00 73.14  ? 48  THR B C   1 
ATOM   6222  O O   . THR B 1 28  ? 149.303 125.218 68.229  1.00 73.40  ? 48  THR B O   1 
ATOM   6223  C CB  . THR B 1 28  ? 151.403 122.733 68.796  1.00 70.59  ? 48  THR B CB  1 
ATOM   6224  O OG1 . THR B 1 28  ? 151.911 123.722 67.900  1.00 72.75  ? 48  THR B OG1 1 
ATOM   6225  C CG2 . THR B 1 28  ? 151.683 121.339 68.277  1.00 70.29  ? 48  THR B CG2 1 
ATOM   6226  N N   . VAL B 1 29  ? 149.929 125.003 70.393  1.00 77.34  ? 49  VAL B N   1 
ATOM   6227  C CA  . VAL B 1 29  ? 149.628 126.376 70.772  1.00 81.44  ? 49  VAL B CA  1 
ATOM   6228  C C   . VAL B 1 29  ? 150.393 127.354 69.877  1.00 83.71  ? 49  VAL B C   1 
ATOM   6229  O O   . VAL B 1 29  ? 149.964 128.492 69.706  1.00 83.75  ? 49  VAL B O   1 
ATOM   6230  C CB  . VAL B 1 29  ? 149.936 126.619 72.263  1.00 84.12  ? 49  VAL B CB  1 
ATOM   6231  C CG1 . VAL B 1 29  ? 151.430 126.757 72.524  1.00 85.42  ? 49  VAL B CG1 1 
ATOM   6232  C CG2 . VAL B 1 29  ? 149.183 127.827 72.806  1.00 83.90  ? 49  VAL B CG2 1 
ATOM   6233  N N   . ASP B 1 30  ? 151.527 126.914 69.315  1.00 85.49  ? 50  ASP B N   1 
ATOM   6234  C CA  . ASP B 1 30  ? 152.347 127.766 68.466  1.00 88.25  ? 50  ASP B CA  1 
ATOM   6235  C C   . ASP B 1 30  ? 151.824 127.760 67.027  1.00 85.64  ? 50  ASP B C   1 
ATOM   6236  O O   . ASP B 1 30  ? 152.008 128.736 66.304  1.00 86.04  ? 50  ASP B O   1 
ATOM   6237  C CB  . ASP B 1 30  ? 153.817 127.348 68.553  1.00 93.19  ? 50  ASP B CB  1 
ATOM   6238  C CG  . ASP B 1 30  ? 154.766 128.242 67.770  1.00 97.34  ? 50  ASP B CG  1 
ATOM   6239  O OD1 . ASP B 1 30  ? 154.616 128.307 66.535  1.00 97.78  ? 50  ASP B OD1 1 
ATOM   6240  O OD2 . ASP B 1 30  ? 155.653 128.861 68.401  1.00 98.90  ? 50  ASP B OD2 1 
ATOM   6241  N N   . LYS B 1 31  ? 151.096 126.703 66.640  1.00 83.35  ? 51  LYS B N   1 
ATOM   6242  C CA  . LYS B 1 31  ? 150.702 126.521 65.252  1.00 83.08  ? 51  LYS B CA  1 
ATOM   6243  C C   . LYS B 1 31  ? 149.185 126.615 65.085  1.00 80.72  ? 51  LYS B C   1 
ATOM   6244  O O   . LYS B 1 31  ? 148.644 126.075 64.126  1.00 79.35  ? 51  LYS B O   1 
ATOM   6245  C CB  . LYS B 1 31  ? 151.222 125.171 64.753  1.00 86.64  ? 51  LYS B CB  1 
ATOM   6246  C CG  . LYS B 1 31  ? 152.703 125.122 64.400  1.00 90.51  ? 51  LYS B CG  1 
ATOM   6247  C CD  . LYS B 1 31  ? 153.032 125.757 63.064  1.00 93.27  ? 51  LYS B CD  1 
ATOM   6248  C CE  . LYS B 1 31  ? 154.480 125.569 62.662  1.00 94.68  ? 51  LYS B CE  1 
ATOM   6249  N NZ  . LYS B 1 31  ? 154.748 126.120 61.313  1.00 94.99  ? 51  LYS B NZ  1 
ATOM   6250  N N   . VAL B 1 32  ? 148.509 127.328 65.994  1.00 79.80  ? 52  VAL B N   1 
ATOM   6251  C CA  . VAL B 1 32  ? 147.059 127.447 65.944  1.00 77.77  ? 52  VAL B CA  1 
ATOM   6252  C C   . VAL B 1 32  ? 146.656 128.279 64.729  1.00 77.17  ? 52  VAL B C   1 
ATOM   6253  O O   . VAL B 1 32  ? 145.726 127.917 64.012  1.00 77.08  ? 52  VAL B O   1 
ATOM   6254  C CB  . VAL B 1 32  ? 146.489 128.053 67.242  1.00 77.37  ? 52  VAL B CB  1 
ATOM   6255  C CG1 . VAL B 1 32  ? 145.012 128.400 67.115  1.00 76.52  ? 52  VAL B CG1 1 
ATOM   6256  C CG2 . VAL B 1 32  ? 146.719 127.140 68.434  1.00 79.26  ? 52  VAL B CG2 1 
ATOM   6257  N N   . HIS B 1 33  ? 147.372 129.387 64.507  1.00 77.73  ? 53  HIS B N   1 
ATOM   6258  C CA  . HIS B 1 33  ? 147.014 130.345 63.472  1.00 78.81  ? 53  HIS B CA  1 
ATOM   6259  C C   . HIS B 1 33  ? 147.181 129.733 62.083  1.00 78.09  ? 53  HIS B C   1 
ATOM   6260  O O   . HIS B 1 33  ? 146.384 130.009 61.191  1.00 77.60  ? 53  HIS B O   1 
ATOM   6261  C CB  . HIS B 1 33  ? 147.824 131.632 63.641  1.00 80.31  ? 53  HIS B CB  1 
ATOM   6262  C CG  . HIS B 1 33  ? 147.585 132.281 64.960  1.00 81.60  ? 53  HIS B CG  1 
ATOM   6263  N ND1 . HIS B 1 33  ? 146.331 132.663 65.383  1.00 81.07  ? 53  HIS B ND1 1 
ATOM   6264  C CD2 . HIS B 1 33  ? 148.423 132.587 65.956  1.00 83.42  ? 53  HIS B CD2 1 
ATOM   6265  C CE1 . HIS B 1 33  ? 146.424 133.200 66.591  1.00 81.51  ? 53  HIS B CE1 1 
ATOM   6266  N NE2 . HIS B 1 33  ? 147.686 133.167 66.959  1.00 82.55  ? 53  HIS B NE2 1 
ATOM   6267  N N   . GLU B 1 34  ? 148.215 128.901 61.911  1.00 78.68  ? 54  GLU B N   1 
ATOM   6268  C CA  . GLU B 1 34  ? 148.447 128.225 60.645  1.00 80.27  ? 54  GLU B CA  1 
ATOM   6269  C C   . GLU B 1 34  ? 147.321 127.228 60.375  1.00 75.90  ? 54  GLU B C   1 
ATOM   6270  O O   . GLU B 1 34  ? 147.032 126.935 59.217  1.00 76.07  ? 54  GLU B O   1 
ATOM   6271  C CB  . GLU B 1 34  ? 149.811 127.529 60.644  1.00 85.98  ? 54  GLU B CB  1 
ATOM   6272  C CG  . GLU B 1 34  ? 150.982 128.474 60.412  1.00 90.78  ? 54  GLU B CG  1 
ATOM   6273  C CD  . GLU B 1 34  ? 151.219 129.516 61.494  1.00 94.25  ? 54  GLU B CD  1 
ATOM   6274  O OE1 . GLU B 1 34  ? 151.156 130.723 61.177  1.00 94.51  ? 54  GLU B OE1 1 
ATOM   6275  O OE2 . GLU B 1 34  ? 151.468 129.119 62.651  1.00 95.68  ? 54  GLU B OE2 1 
ATOM   6276  N N   . ARG B 1 35  ? 146.705 126.716 61.452  1.00 70.43  ? 55  ARG B N   1 
ATOM   6277  C CA  . ARG B 1 35  ? 145.635 125.729 61.374  1.00 66.06  ? 55  ARG B CA  1 
ATOM   6278  C C   . ARG B 1 35  ? 146.137 124.467 60.673  1.00 64.96  ? 55  ARG B C   1 
ATOM   6279  O O   . ARG B 1 35  ? 145.516 123.984 59.730  1.00 64.63  ? 55  ARG B O   1 
ATOM   6280  C CB  . ARG B 1 35  ? 144.386 126.315 60.703  1.00 63.85  ? 55  ARG B CB  1 
ATOM   6281  C CG  . ARG B 1 35  ? 143.454 127.032 61.669  1.00 61.95  ? 55  ARG B CG  1 
ATOM   6282  C CD  . ARG B 1 35  ? 142.253 127.642 60.972  1.00 60.65  ? 55  ARG B CD  1 
ATOM   6283  N NE  . ARG B 1 35  ? 142.600 128.871 60.271  1.00 60.34  ? 55  ARG B NE  1 
ATOM   6284  C CZ  . ARG B 1 35  ? 142.574 129.041 58.952  1.00 60.62  ? 55  ARG B CZ  1 
ATOM   6285  N NH1 . ARG B 1 35  ? 142.248 128.044 58.148  1.00 60.28  ? 55  ARG B NH1 1 
ATOM   6286  N NH2 . ARG B 1 35  ? 142.883 130.220 58.436  1.00 60.83  ? 55  ARG B NH2 1 
ATOM   6287  N N   . LYS B 1 36  ? 147.272 123.944 61.150  1.00 64.78  ? 56  LYS B N   1 
ATOM   6288  C CA  . LYS B 1 36  ? 147.730 122.614 60.779  1.00 64.13  ? 56  LYS B CA  1 
ATOM   6289  C C   . LYS B 1 36  ? 147.752 121.756 62.041  1.00 58.98  ? 56  LYS B C   1 
ATOM   6290  O O   . LYS B 1 36  ? 148.208 122.201 63.093  1.00 57.98  ? 56  LYS B O   1 
ATOM   6291  C CB  . LYS B 1 36  ? 149.098 122.659 60.088  1.00 68.03  ? 56  LYS B CB  1 
ATOM   6292  C CG  . LYS B 1 36  ? 150.316 122.692 61.006  1.00 71.69  ? 56  LYS B CG  1 
ATOM   6293  C CD  . LYS B 1 36  ? 151.645 122.593 60.277  1.00 75.49  ? 56  LYS B CD  1 
ATOM   6294  C CE  . LYS B 1 36  ? 151.799 121.334 59.445  1.00 77.78  ? 56  LYS B CE  1 
ATOM   6295  N NZ  . LYS B 1 36  ? 151.413 120.111 60.193  1.00 78.37  ? 56  LYS B NZ  1 
ATOM   6296  N N   . CYS B 1 37  ? 147.251 120.522 61.923  1.00 54.91  ? 57  CYS B N   1 
ATOM   6297  C CA  . CYS B 1 37  ? 147.067 119.660 63.080  1.00 51.92  ? 57  CYS B CA  1 
ATOM   6298  C C   . CYS B 1 37  ? 148.101 118.539 63.075  1.00 50.08  ? 57  CYS B C   1 
ATOM   6299  O O   . CYS B 1 37  ? 148.629 118.169 62.028  1.00 49.73  ? 57  CYS B O   1 
ATOM   6300  C CB  . CYS B 1 37  ? 145.643 119.121 63.147  1.00 49.97  ? 57  CYS B CB  1 
ATOM   6301  S SG  . CYS B 1 37  ? 144.949 118.632 61.546  1.00 47.06  ? 57  CYS B SG  1 
ATOM   6302  N N   . GLY B 1 38  ? 148.370 118.009 64.275  1.00 48.37  ? 58  GLY B N   1 
ATOM   6303  C CA  . GLY B 1 38  ? 149.531 117.171 64.521  1.00 47.79  ? 58  GLY B CA  1 
ATOM   6304  C C   . GLY B 1 38  ? 149.297 115.705 64.167  1.00 46.53  ? 58  GLY B C   1 
ATOM   6305  O O   . GLY B 1 38  ? 148.817 115.386 63.079  1.00 46.28  ? 58  GLY B O   1 
ATOM   6306  N N   . ALA B 1 39  ? 149.654 114.819 65.104  1.00 45.14  ? 59  ALA B N   1 
ATOM   6307  C CA  . ALA B 1 39  ? 149.767 113.398 64.821  1.00 44.55  ? 59  ALA B CA  1 
ATOM   6308  C C   . ALA B 1 39  ? 148.384 112.777 64.642  1.00 42.10  ? 59  ALA B C   1 
ATOM   6309  O O   . ALA B 1 39  ? 147.398 113.253 65.198  1.00 41.91  ? 59  ALA B O   1 
ATOM   6310  C CB  . ALA B 1 39  ? 150.544 112.715 65.919  1.00 45.49  ? 59  ALA B CB  1 
ATOM   6311  N N   . VAL B 1 40  ? 148.343 111.708 63.842  1.00 39.11  ? 60  VAL B N   1 
ATOM   6312  C CA  . VAL B 1 40  ? 147.116 110.996 63.527  1.00 37.18  ? 60  VAL B CA  1 
ATOM   6313  C C   . VAL B 1 40  ? 146.687 110.171 64.739  1.00 35.85  ? 60  VAL B C   1 
ATOM   6314  O O   . VAL B 1 40  ? 147.529 109.652 65.470  1.00 35.97  ? 60  VAL B O   1 
ATOM   6315  C CB  . VAL B 1 40  ? 147.300 110.114 62.276  1.00 37.62  ? 60  VAL B CB  1 
ATOM   6316  C CG1 . VAL B 1 40  ? 148.467 109.148 62.417  1.00 38.40  ? 60  VAL B CG1 1 
ATOM   6317  C CG2 . VAL B 1 40  ? 146.033 109.354 61.924  1.00 37.58  ? 60  VAL B CG2 1 
ATOM   6318  N N   . ARG B 1 41  ? 145.367 110.041 64.922  1.00 34.33  ? 61  ARG B N   1 
ATOM   6319  C CA  . ARG B 1 41  ? 144.786 109.313 66.039  1.00 32.86  ? 61  ARG B CA  1 
ATOM   6320  C C   . ARG B 1 41  ? 144.164 108.015 65.537  1.00 32.76  ? 61  ARG B C   1 
ATOM   6321  O O   . ARG B 1 41  ? 143.620 107.973 64.436  1.00 33.08  ? 61  ARG B O   1 
ATOM   6322  C CB  . ARG B 1 41  ? 143.715 110.167 66.721  1.00 32.01  ? 61  ARG B CB  1 
ATOM   6323  C CG  . ARG B 1 41  ? 144.145 111.605 66.966  1.00 32.13  ? 61  ARG B CG  1 
ATOM   6324  C CD  . ARG B 1 41  ? 143.092 112.432 67.669  1.00 32.28  ? 61  ARG B CD  1 
ATOM   6325  N NE  . ARG B 1 41  ? 142.821 111.993 69.030  1.00 32.52  ? 61  ARG B NE  1 
ATOM   6326  C CZ  . ARG B 1 41  ? 142.085 112.671 69.903  1.00 33.11  ? 61  ARG B CZ  1 
ATOM   6327  N NH1 . ARG B 1 41  ? 141.551 113.830 69.563  1.00 33.13  ? 61  ARG B NH1 1 
ATOM   6328  N NH2 . ARG B 1 41  ? 141.888 112.191 71.119  1.00 33.41  ? 61  ARG B NH2 1 
ATOM   6329  N N   . GLU B 1 42  ? 144.227 106.965 66.365  1.00 32.94  ? 62  GLU B N   1 
ATOM   6330  C CA  . GLU B 1 42  ? 143.708 105.658 65.992  1.00 33.34  ? 62  GLU B CA  1 
ATOM   6331  C C   . GLU B 1 42  ? 142.291 105.487 66.528  1.00 31.61  ? 62  GLU B C   1 
ATOM   6332  O O   . GLU B 1 42  ? 141.364 105.254 65.758  1.00 31.94  ? 62  GLU B O   1 
ATOM   6333  C CB  . GLU B 1 42  ? 144.603 104.541 66.524  1.00 35.83  ? 62  GLU B CB  1 
ATOM   6334  C CG  . GLU B 1 42  ? 144.034 103.152 66.285  1.00 38.13  ? 62  GLU B CG  1 
ATOM   6335  C CD  . GLU B 1 42  ? 144.895 102.009 66.800  1.00 40.60  ? 62  GLU B CD  1 
ATOM   6336  O OE1 . GLU B 1 42  ? 145.380 102.087 67.950  1.00 41.82  ? 62  GLU B OE1 1 
ATOM   6337  O OE2 . GLU B 1 42  ? 145.073 101.036 66.044  1.00 41.60  ? 62  GLU B OE2 1 
ATOM   6338  N N   . GLN B 1 43  ? 142.138 105.575 67.853  1.00 29.99  ? 63  GLN B N   1 
ATOM   6339  C CA  . GLN B 1 43  ? 140.852 105.346 68.488  1.00 28.99  ? 63  GLN B CA  1 
ATOM   6340  C C   . GLN B 1 43  ? 139.851 106.395 68.016  1.00 27.49  ? 63  GLN B C   1 
ATOM   6341  O O   . GLN B 1 43  ? 138.739 106.060 67.613  1.00 27.97  ? 63  GLN B O   1 
ATOM   6342  C CB  . GLN B 1 43  ? 140.981 105.386 70.013  1.00 29.85  ? 63  GLN B CB  1 
ATOM   6343  C CG  . GLN B 1 43  ? 142.032 104.442 70.578  1.00 30.61  ? 63  GLN B CG  1 
ATOM   6344  C CD  . GLN B 1 43  ? 142.031 103.076 69.938  1.00 31.14  ? 63  GLN B CD  1 
ATOM   6345  O OE1 . GLN B 1 43  ? 143.063 102.578 69.499  1.00 30.80  ? 63  GLN B OE1 1 
ATOM   6346  N NE2 . GLN B 1 43  ? 140.866 102.449 69.893  1.00 31.83  ? 63  GLN B NE2 1 
ATOM   6347  N N   . TYR B 1 44  ? 140.251 107.669 68.064  1.00 26.17  ? 64  TYR B N   1 
ATOM   6348  C CA  . TYR B 1 44  ? 139.348 108.768 67.756  1.00 25.34  ? 64  TYR B CA  1 
ATOM   6349  C C   . TYR B 1 44  ? 139.374 109.114 66.272  1.00 24.61  ? 64  TYR B C   1 
ATOM   6350  O O   . TYR B 1 44  ? 138.571 109.927 65.820  1.00 24.43  ? 64  TYR B O   1 
ATOM   6351  C CB  . TYR B 1 44  ? 139.700 110.006 68.580  1.00 25.66  ? 64  TYR B CB  1 
ATOM   6352  C CG  . TYR B 1 44  ? 139.091 110.019 69.954  1.00 26.27  ? 64  TYR B CG  1 
ATOM   6353  C CD1 . TYR B 1 44  ? 138.978 108.851 70.687  1.00 26.79  ? 64  TYR B CD1 1 
ATOM   6354  C CD2 . TYR B 1 44  ? 138.655 111.197 70.540  1.00 26.63  ? 64  TYR B CD2 1 
ATOM   6355  C CE1 . TYR B 1 44  ? 138.429 108.846 71.956  1.00 27.17  ? 64  TYR B CE1 1 
ATOM   6356  C CE2 . TYR B 1 44  ? 138.103 111.213 71.810  1.00 26.74  ? 64  TYR B CE2 1 
ATOM   6357  C CZ  . TYR B 1 44  ? 137.992 110.030 72.519  1.00 27.05  ? 64  TYR B CZ  1 
ATOM   6358  O OH  . TYR B 1 44  ? 137.457 110.002 73.778  1.00 27.47  ? 64  TYR B OH  1 
ATOM   6359  N N   . GLY B 1 45  ? 140.292 108.500 65.519  1.00 24.43  ? 65  GLY B N   1 
ATOM   6360  C CA  . GLY B 1 45  ? 140.486 108.862 64.128  1.00 24.45  ? 65  GLY B CA  1 
ATOM   6361  C C   . GLY B 1 45  ? 140.105 107.730 63.187  1.00 24.33  ? 65  GLY B C   1 
ATOM   6362  O O   . GLY B 1 45  ? 138.946 107.590 62.819  1.00 24.65  ? 65  GLY B O   1 
ATOM   6363  N N   . ILE B 1 46  ? 141.094 106.909 62.840  1.00 24.72  ? 66  ILE B N   1 
ATOM   6364  C CA  . ILE B 1 46  ? 140.951 105.937 61.775  1.00 25.47  ? 66  ILE B CA  1 
ATOM   6365  C C   . ILE B 1 46  ? 139.848 104.941 62.119  1.00 25.91  ? 66  ILE B C   1 
ATOM   6366  O O   . ILE B 1 46  ? 139.141 104.488 61.225  1.00 26.55  ? 66  ILE B O   1 
ATOM   6367  C CB  . ILE B 1 46  ? 142.299 105.246 61.502  1.00 26.19  ? 66  ILE B CB  1 
ATOM   6368  C CG1 . ILE B 1 46  ? 143.403 106.274 61.243  1.00 26.98  ? 66  ILE B CG1 1 
ATOM   6369  C CG2 . ILE B 1 46  ? 142.191 104.245 60.362  1.00 26.39  ? 66  ILE B CG2 1 
ATOM   6370  C CD1 . ILE B 1 46  ? 143.099 107.265 60.143  1.00 27.34  ? 66  ILE B CD1 1 
ATOM   6371  N N   . GLN B 1 47  ? 139.681 104.606 63.401  1.00 26.06  ? 67  GLN B N   1 
ATOM   6372  C CA  . GLN B 1 47  ? 138.670 103.628 63.772  1.00 26.29  ? 67  GLN B CA  1 
ATOM   6373  C C   . GLN B 1 47  ? 137.277 104.159 63.447  1.00 25.81  ? 67  GLN B C   1 
ATOM   6374  O O   . GLN B 1 47  ? 136.474 103.440 62.864  1.00 26.15  ? 67  GLN B O   1 
ATOM   6375  C CB  . GLN B 1 47  ? 138.794 103.226 65.239  1.00 26.99  ? 67  GLN B CB  1 
ATOM   6376  C CG  . GLN B 1 47  ? 139.958 102.281 65.488  1.00 27.81  ? 67  GLN B CG  1 
ATOM   6377  C CD  . GLN B 1 47  ? 139.865 101.581 66.817  1.00 28.62  ? 67  GLN B CD  1 
ATOM   6378  O OE1 . GLN B 1 47  ? 138.907 101.755 67.564  1.00 28.98  ? 67  GLN B OE1 1 
ATOM   6379  N NE2 . GLN B 1 47  ? 140.867 100.770 67.116  1.00 29.38  ? 67  GLN B NE2 1 
ATOM   6380  N N   . ARG B 1 48  ? 137.004 105.419 63.793  1.00 25.29  ? 68  ARG B N   1 
ATOM   6381  C CA  . ARG B 1 48  ? 135.695 106.004 63.548  1.00 24.68  ? 68  ARG B CA  1 
ATOM   6382  C C   . ARG B 1 48  ? 135.461 106.189 62.050  1.00 25.39  ? 68  ARG B C   1 
ATOM   6383  O O   . ARG B 1 48  ? 134.351 105.961 61.573  1.00 26.01  ? 68  ARG B O   1 
ATOM   6384  C CB  . ARG B 1 48  ? 135.552 107.325 64.303  1.00 23.63  ? 68  ARG B CB  1 
ATOM   6385  C CG  . ARG B 1 48  ? 135.504 107.152 65.811  1.00 23.15  ? 68  ARG B CG  1 
ATOM   6386  C CD  . ARG B 1 48  ? 135.361 108.484 66.506  1.00 22.93  ? 68  ARG B CD  1 
ATOM   6387  N NE  . ARG B 1 48  ? 135.273 108.313 67.945  1.00 22.99  ? 68  ARG B NE  1 
ATOM   6388  C CZ  . ARG B 1 48  ? 135.298 109.310 68.821  1.00 23.49  ? 68  ARG B CZ  1 
ATOM   6389  N NH1 . ARG B 1 48  ? 135.405 110.563 68.407  1.00 23.42  ? 68  ARG B NH1 1 
ATOM   6390  N NH2 . ARG B 1 48  ? 135.247 109.049 70.118  1.00 23.91  ? 68  ARG B NH2 1 
ATOM   6391  N N   . VAL B 1 49  ? 136.503 106.594 61.314  1.00 26.16  ? 69  VAL B N   1 
ATOM   6392  C CA  . VAL B 1 49  ? 136.395 106.784 59.875  1.00 27.19  ? 69  VAL B CA  1 
ATOM   6393  C C   . VAL B 1 49  ? 136.056 105.449 59.216  1.00 28.93  ? 69  VAL B C   1 
ATOM   6394  O O   . VAL B 1 49  ? 135.154 105.384 58.385  1.00 29.89  ? 69  VAL B O   1 
ATOM   6395  C CB  . VAL B 1 49  ? 137.683 107.388 59.282  1.00 27.10  ? 69  VAL B CB  1 
ATOM   6396  C CG1 . VAL B 1 49  ? 137.702 107.323 57.763  1.00 27.20  ? 69  VAL B CG1 1 
ATOM   6397  C CG2 . VAL B 1 49  ? 137.904 108.816 59.752  1.00 27.22  ? 69  VAL B CG2 1 
ATOM   6398  N N   . GLU B 1 50  ? 136.789 104.393 59.582  1.00 30.47  ? 70  GLU B N   1 
ATOM   6399  C CA  . GLU B 1 50  ? 136.561 103.075 59.014  1.00 32.24  ? 70  GLU B CA  1 
ATOM   6400  C C   . GLU B 1 50  ? 135.192 102.552 59.435  1.00 32.81  ? 70  GLU B C   1 
ATOM   6401  O O   . GLU B 1 50  ? 134.537 101.868 58.654  1.00 33.51  ? 70  GLU B O   1 
ATOM   6402  C CB  . GLU B 1 50  ? 137.668 102.106 59.428  1.00 33.81  ? 70  GLU B CB  1 
ATOM   6403  C CG  . GLU B 1 50  ? 138.944 102.296 58.634  1.00 35.85  ? 70  GLU B CG  1 
ATOM   6404  C CD  . GLU B 1 50  ? 138.772 102.075 57.139  1.00 37.77  ? 70  GLU B CD  1 
ATOM   6405  O OE1 . GLU B 1 50  ? 138.099 101.089 56.760  1.00 38.46  ? 70  GLU B OE1 1 
ATOM   6406  O OE2 . GLU B 1 50  ? 139.336 102.863 56.349  1.00 38.90  ? 70  GLU B OE2 1 
ATOM   6407  N N   . ALA B 1 51  ? 134.770 102.874 60.663  1.00 33.03  ? 71  ALA B N   1 
ATOM   6408  C CA  . ALA B 1 51  ? 133.477 102.440 61.165  1.00 33.34  ? 71  ALA B CA  1 
ATOM   6409  C C   . ALA B 1 51  ? 132.365 103.031 60.306  1.00 34.53  ? 71  ALA B C   1 
ATOM   6410  O O   . ALA B 1 51  ? 131.432 102.325 59.937  1.00 35.55  ? 71  ALA B O   1 
ATOM   6411  C CB  . ALA B 1 51  ? 133.317 102.829 62.611  1.00 32.97  ? 71  ALA B CB  1 
ATOM   6412  N N   . MET B 1 52  ? 132.473 104.326 59.991  1.00 35.35  ? 72  MET B N   1 
ATOM   6413  C CA  . MET B 1 52  ? 131.468 104.986 59.178  1.00 36.05  ? 72  MET B CA  1 
ATOM   6414  C C   . MET B 1 52  ? 131.491 104.418 57.763  1.00 37.15  ? 72  MET B C   1 
ATOM   6415  O O   . MET B 1 52  ? 130.441 104.126 57.199  1.00 38.10  ? 72  MET B O   1 
ATOM   6416  C CB  . MET B 1 52  ? 131.677 106.501 59.127  1.00 36.16  ? 72  MET B CB  1 
ATOM   6417  C CG  . MET B 1 52  ? 130.704 107.197 58.197  1.00 37.13  ? 72  MET B CG  1 
ATOM   6418  S SD  . MET B 1 52  ? 130.020 108.709 58.932  1.00 38.81  ? 72  MET B SD  1 
ATOM   6419  C CE  . MET B 1 52  ? 128.721 109.093 57.762  1.00 38.62  ? 72  MET B CE  1 
ATOM   6420  N N   . LEU B 1 53  ? 132.693 104.238 57.205  1.00 38.92  ? 73  LEU B N   1 
ATOM   6421  C CA  . LEU B 1 53  ? 132.837 103.739 55.846  1.00 40.88  ? 73  LEU B CA  1 
ATOM   6422  C C   . LEU B 1 53  ? 132.258 102.331 55.723  1.00 42.58  ? 73  LEU B C   1 
ATOM   6423  O O   . LEU B 1 53  ? 131.768 101.964 54.657  1.00 44.31  ? 73  LEU B O   1 
ATOM   6424  C CB  . LEU B 1 53  ? 134.314 103.754 55.439  1.00 41.62  ? 73  LEU B CB  1 
ATOM   6425  C CG  . LEU B 1 53  ? 134.888 105.116 55.055  1.00 42.41  ? 73  LEU B CG  1 
ATOM   6426  C CD1 . LEU B 1 53  ? 136.400 105.039 54.900  1.00 42.78  ? 73  LEU B CD1 1 
ATOM   6427  C CD2 . LEU B 1 53  ? 134.250 105.640 53.778  1.00 43.06  ? 73  LEU B CD2 1 
ATOM   6428  N N   . HIS B 1 54  ? 132.310 101.544 56.804  1.00 43.89  ? 74  HIS B N   1 
ATOM   6429  C CA  . HIS B 1 54  ? 131.809 100.180 56.758  1.00 45.36  ? 74  HIS B CA  1 
ATOM   6430  C C   . HIS B 1 54  ? 130.312 100.139 57.044  1.00 46.67  ? 74  HIS B C   1 
ATOM   6431  O O   . HIS B 1 54  ? 129.608 99.336  56.439  1.00 48.41  ? 74  HIS B O   1 
ATOM   6432  C CB  . HIS B 1 54  ? 132.555 99.265  57.732  1.00 45.73  ? 74  HIS B CB  1 
ATOM   6433  C CG  . HIS B 1 54  ? 132.165 97.832  57.594  1.00 46.06  ? 74  HIS B CG  1 
ATOM   6434  N ND1 . HIS B 1 54  ? 132.165 97.154  56.395  1.00 46.35  ? 74  HIS B ND1 1 
ATOM   6435  C CD2 . HIS B 1 54  ? 131.706 96.971  58.503  1.00 46.77  ? 74  HIS B CD2 1 
ATOM   6436  C CE1 . HIS B 1 54  ? 131.740 95.915  56.595  1.00 47.27  ? 74  HIS B CE1 1 
ATOM   6437  N NE2 . HIS B 1 54  ? 131.455 95.782  57.871  1.00 47.20  ? 74  HIS B NE2 1 
ATOM   6438  N N   . THR B 1 55  ? 129.842 100.969 57.983  1.00 46.34  ? 75  THR B N   1 
ATOM   6439  C CA  . THR B 1 55  ? 128.437 100.969 58.363  1.00 46.02  ? 75  THR B CA  1 
ATOM   6440  C C   . THR B 1 55  ? 127.585 101.436 57.187  1.00 47.00  ? 75  THR B C   1 
ATOM   6441  O O   . THR B 1 55  ? 126.477 100.939 57.001  1.00 47.81  ? 75  THR B O   1 
ATOM   6442  C CB  . THR B 1 55  ? 128.185 101.832 59.607  1.00 45.22  ? 75  THR B CB  1 
ATOM   6443  O OG1 . THR B 1 55  ? 128.663 101.113 60.743  1.00 45.07  ? 75  THR B OG1 1 
ATOM   6444  C CG2 . THR B 1 55  ? 126.730 102.190 59.821  1.00 45.37  ? 75  THR B CG2 1 
ATOM   6445  N N   . LEU B 1 56  ? 128.096 102.401 56.414  1.00 48.80  ? 76  LEU B N   1 
ATOM   6446  C CA  . LEU B 1 56  ? 127.365 102.880 55.254  1.00 50.92  ? 76  LEU B CA  1 
ATOM   6447  C C   . LEU B 1 56  ? 127.219 101.762 54.229  1.00 54.71  ? 76  LEU B C   1 
ATOM   6448  O O   . LEU B 1 56  ? 126.145 101.598 53.653  1.00 56.17  ? 76  LEU B O   1 
ATOM   6449  C CB  . LEU B 1 56  ? 128.057 104.104 54.646  1.00 51.11  ? 76  LEU B CB  1 
ATOM   6450  C CG  . LEU B 1 56  ? 127.665 105.460 55.240  1.00 51.31  ? 76  LEU B CG  1 
ATOM   6451  C CD1 . LEU B 1 56  ? 127.802 106.560 54.203  1.00 51.65  ? 76  LEU B CD1 1 
ATOM   6452  C CD2 . LEU B 1 56  ? 126.254 105.460 55.815  1.00 51.40  ? 76  LEU B CD2 1 
ATOM   6453  N N   . GLU B 1 57  ? 128.286 100.985 54.011  1.00 59.00  ? 77  GLU B N   1 
ATOM   6454  C CA  . GLU B 1 57  ? 128.228 99.917  53.024  1.00 63.75  ? 77  GLU B CA  1 
ATOM   6455  C C   . GLU B 1 57  ? 127.346 98.783  53.549  1.00 64.65  ? 77  GLU B C   1 
ATOM   6456  O O   . GLU B 1 57  ? 126.679 98.108  52.768  1.00 66.38  ? 77  GLU B O   1 
ATOM   6457  C CB  . GLU B 1 57  ? 129.631 99.466  52.613  1.00 66.96  ? 77  GLU B CB  1 
ATOM   6458  C CG  . GLU B 1 57  ? 130.241 98.388  53.480  1.00 69.66  ? 77  GLU B CG  1 
ATOM   6459  C CD  . GLU B 1 57  ? 131.640 97.978  53.049  1.00 73.24  ? 77  GLU B CD  1 
ATOM   6460  O OE1 . GLU B 1 57  ? 132.273 98.712  52.254  1.00 74.27  ? 77  GLU B OE1 1 
ATOM   6461  O OE2 . GLU B 1 57  ? 132.091 96.909  53.490  1.00 74.87  ? 77  GLU B OE2 1 
ATOM   6462  N N   . ARG B 1 58  ? 127.331 98.581  54.871  1.00 64.52  ? 78  ARG B N   1 
ATOM   6463  C CA  . ARG B 1 58  ? 126.457 97.592  55.488  1.00 65.79  ? 78  ARG B CA  1 
ATOM   6464  C C   . ARG B 1 58  ? 124.993 97.978  55.275  1.00 65.73  ? 78  ARG B C   1 
ATOM   6465  O O   . ARG B 1 58  ? 124.162 97.116  54.992  1.00 67.14  ? 78  ARG B O   1 
ATOM   6466  C CB  . ARG B 1 58  ? 126.795 97.446  56.976  1.00 66.87  ? 78  ARG B CB  1 
ATOM   6467  C CG  . ARG B 1 58  ? 125.693 96.838  57.826  1.00 68.36  ? 78  ARG B CG  1 
ATOM   6468  C CD  . ARG B 1 58  ? 126.163 96.669  59.256  1.00 69.28  ? 78  ARG B CD  1 
ATOM   6469  N NE  . ARG B 1 58  ? 126.918 95.438  59.411  1.00 70.30  ? 78  ARG B NE  1 
ATOM   6470  C CZ  . ARG B 1 58  ? 126.675 94.509  60.331  1.00 70.93  ? 78  ARG B CZ  1 
ATOM   6471  N NH1 . ARG B 1 58  ? 125.718 94.682  61.228  1.00 70.67  ? 78  ARG B NH1 1 
ATOM   6472  N NH2 . ARG B 1 58  ? 127.414 93.413  60.372  1.00 71.31  ? 78  ARG B NH2 1 
ATOM   6473  N N   . ILE B 1 59  ? 124.684 99.271  55.428  1.00 64.48  ? 79  ILE B N   1 
ATOM   6474  C CA  . ILE B 1 59  ? 123.340 99.781  55.199  1.00 63.70  ? 79  ILE B CA  1 
ATOM   6475  C C   . ILE B 1 59  ? 122.972 99.596  53.729  1.00 65.76  ? 79  ILE B C   1 
ATOM   6476  O O   . ILE B 1 59  ? 121.859 99.189  53.424  1.00 66.58  ? 79  ILE B O   1 
ATOM   6477  C CB  . ILE B 1 59  ? 123.224 101.252 55.652  1.00 61.71  ? 79  ILE B CB  1 
ATOM   6478  C CG1 . ILE B 1 59  ? 123.085 101.346 57.177  1.00 59.95  ? 79  ILE B CG1 1 
ATOM   6479  C CG2 . ILE B 1 59  ? 122.089 101.968 54.930  1.00 61.36  ? 79  ILE B CG2 1 
ATOM   6480  C CD1 . ILE B 1 59  ? 123.307 102.734 57.732  1.00 59.20  ? 79  ILE B CD1 1 
ATOM   6481  N N   . ASN B 1 60  ? 123.906 99.904  52.826  1.00 68.95  ? 80  ASN B N   1 
ATOM   6482  C CA  . ASN B 1 60  ? 123.660 99.806  51.395  1.00 72.89  ? 80  ASN B CA  1 
ATOM   6483  C C   . ASN B 1 60  ? 123.350 98.364  51.002  1.00 76.49  ? 80  ASN B C   1 
ATOM   6484  O O   . ASN B 1 60  ? 122.464 98.129  50.184  1.00 76.75  ? 80  ASN B O   1 
ATOM   6485  C CB  . ASN B 1 60  ? 124.837 100.355 50.586  1.00 72.74  ? 80  ASN B CB  1 
ATOM   6486  C CG  . ASN B 1 60  ? 124.989 101.850 50.744  1.00 72.24  ? 80  ASN B CG  1 
ATOM   6487  O OD1 . ASN B 1 60  ? 124.199 102.481 51.444  1.00 70.86  ? 80  ASN B OD1 1 
ATOM   6488  N ND2 . ASN B 1 60  ? 125.992 102.419 50.095  1.00 73.08  ? 80  ASN B ND2 1 
ATOM   6489  N N   . SER B 1 61  ? 124.090 97.412  51.577  1.00 80.90  ? 81  SER B N   1 
ATOM   6490  C CA  . SER B 1 61  ? 123.884 96.003  51.282  1.00 85.58  ? 81  SER B CA  1 
ATOM   6491  C C   . SER B 1 61  ? 122.553 95.519  51.857  1.00 88.89  ? 81  SER B C   1 
ATOM   6492  O O   . SER B 1 61  ? 121.889 94.680  51.251  1.00 89.69  ? 81  SER B O   1 
ATOM   6493  C CB  . SER B 1 61  ? 125.036 95.173  51.785  1.00 87.05  ? 81  SER B CB  1 
ATOM   6494  O OG  . SER B 1 61  ? 125.190 95.320  53.187  1.00 87.88  ? 81  SER B OG  1 
ATOM   6495  N N   . ASP B 1 62  ? 122.166 96.053  53.024  1.00 92.84  ? 82  ASP B N   1 
ATOM   6496  C CA  . ASP B 1 62  ? 120.948 95.628  53.695  1.00 97.68  ? 82  ASP B CA  1 
ATOM   6497  C C   . ASP B 1 62  ? 119.740 96.188  52.942  1.00 101.75 ? 82  ASP B C   1 
ATOM   6498  O O   . ASP B 1 62  ? 119.584 97.402  52.838  1.00 101.73 ? 82  ASP B O   1 
ATOM   6499  C CB  . ASP B 1 62  ? 120.953 96.064  55.163  1.00 99.12  ? 82  ASP B CB  1 
ATOM   6500  C CG  . ASP B 1 62  ? 119.996 95.283  56.050  1.00 100.21 ? 82  ASP B CG  1 
ATOM   6501  O OD1 . ASP B 1 62  ? 119.363 94.332  55.545  1.00 100.62 ? 82  ASP B OD1 1 
ATOM   6502  O OD2 . ASP B 1 62  ? 119.894 95.629  57.244  1.00 100.60 ? 82  ASP B OD2 1 
ATOM   6503  N N   . PRO B 1 63  ? 118.845 95.339  52.383  1.00 106.74 ? 83  PRO B N   1 
ATOM   6504  C CA  . PRO B 1 63  ? 117.708 95.826  51.599  1.00 108.46 ? 83  PRO B CA  1 
ATOM   6505  C C   . PRO B 1 63  ? 116.534 96.346  52.428  1.00 107.50 ? 83  PRO B C   1 
ATOM   6506  O O   . PRO B 1 63  ? 115.699 97.090  51.912  1.00 107.21 ? 83  PRO B O   1 
ATOM   6507  C CB  . PRO B 1 63  ? 117.246 94.606  50.782  1.00 109.26 ? 83  PRO B CB  1 
ATOM   6508  C CG  . PRO B 1 63  ? 118.167 93.459  51.179  1.00 109.70 ? 83  PRO B CG  1 
ATOM   6509  C CD  . PRO B 1 63  ? 118.875 93.874  52.451  1.00 108.34 ? 83  PRO B CD  1 
ATOM   6510  N N   . THR B 1 64  ? 116.477 95.956  53.710  1.00 105.28 ? 84  THR B N   1 
ATOM   6511  C CA  . THR B 1 64  ? 115.364 96.312  54.577  1.00 104.28 ? 84  THR B CA  1 
ATOM   6512  C C   . THR B 1 64  ? 115.425 97.783  54.990  1.00 102.57 ? 84  THR B C   1 
ATOM   6513  O O   . THR B 1 64  ? 114.419 98.328  55.436  1.00 102.91 ? 84  THR B O   1 
ATOM   6514  C CB  . THR B 1 64  ? 115.318 95.427  55.830  1.00 105.49 ? 84  THR B CB  1 
ATOM   6515  O OG1 . THR B 1 64  ? 114.064 95.650  56.477  1.00 105.86 ? 84  THR B OG1 1 
ATOM   6516  C CG2 . THR B 1 64  ? 116.444 95.701  56.803  1.00 106.34 ? 84  THR B CG2 1 
ATOM   6517  N N   . LEU B 1 65  ? 116.607 98.407  54.876  1.00 100.13 ? 85  LEU B N   1 
ATOM   6518  C CA  . LEU B 1 65  ? 116.787 99.806  55.237  1.00 97.30  ? 85  LEU B CA  1 
ATOM   6519  C C   . LEU B 1 65  ? 117.278 100.593 54.025  1.00 95.25  ? 85  LEU B C   1 
ATOM   6520  O O   . LEU B 1 65  ? 118.241 100.196 53.375  1.00 95.67  ? 85  LEU B O   1 
ATOM   6521  C CB  . LEU B 1 65  ? 117.783 99.895  56.399  1.00 96.83  ? 85  LEU B CB  1 
ATOM   6522  C CG  . LEU B 1 65  ? 118.185 101.303 56.846  1.00 94.97  ? 85  LEU B CG  1 
ATOM   6523  C CD1 . LEU B 1 65  ? 117.025 102.044 57.495  1.00 93.80  ? 85  LEU B CD1 1 
ATOM   6524  C CD2 . LEU B 1 65  ? 119.366 101.247 57.796  1.00 94.99  ? 85  LEU B CD2 1 
ATOM   6525  N N   . LEU B 1 66  ? 116.617 101.730 53.768  1.00 94.90  ? 86  LEU B N   1 
ATOM   6526  C CA  . LEU B 1 66  ? 116.887 102.586 52.617  1.00 96.91  ? 86  LEU B CA  1 
ATOM   6527  C C   . LEU B 1 66  ? 116.969 101.755 51.340  1.00 101.19 ? 86  LEU B C   1 
ATOM   6528  O O   . LEU B 1 66  ? 118.032 101.655 50.733  1.00 102.44 ? 86  LEU B O   1 
ATOM   6529  C CB  . LEU B 1 66  ? 118.191 103.368 52.825  1.00 94.82  ? 86  LEU B CB  1 
ATOM   6530  C CG  . LEU B 1 66  ? 118.055 104.757 53.442  1.00 92.25  ? 86  LEU B CG  1 
ATOM   6531  C CD1 . LEU B 1 66  ? 117.025 105.603 52.705  1.00 92.53  ? 86  LEU B CD1 1 
ATOM   6532  C CD2 . LEU B 1 66  ? 117.695 104.647 54.907  1.00 90.73  ? 86  LEU B CD2 1 
ATOM   6533  N N   . PRO B 1 67  ? 115.859 101.146 50.868  1.00 104.09 ? 87  PRO B N   1 
ATOM   6534  C CA  . PRO B 1 67  ? 115.908 100.294 49.680  1.00 105.61 ? 87  PRO B CA  1 
ATOM   6535  C C   . PRO B 1 67  ? 116.020 101.106 48.390  1.00 107.76 ? 87  PRO B C   1 
ATOM   6536  O O   . PRO B 1 67  ? 115.444 102.187 48.287  1.00 107.03 ? 87  PRO B O   1 
ATOM   6537  C CB  . PRO B 1 67  ? 114.588 99.504  49.718  1.00 105.60 ? 87  PRO B CB  1 
ATOM   6538  C CG  . PRO B 1 67  ? 113.901 99.904  51.018  1.00 105.59 ? 87  PRO B CG  1 
ATOM   6539  C CD  . PRO B 1 67  ? 114.503 101.234 51.428  1.00 104.82 ? 87  PRO B CD  1 
ATOM   6540  N N   . ASN B 1 68  ? 116.819 100.587 47.445  1.00 110.35 ? 88  ASN B N   1 
ATOM   6541  C CA  . ASN B 1 68  ? 116.859 101.022 46.056  1.00 112.84 ? 88  ASN B CA  1 
ATOM   6542  C C   . ASN B 1 68  ? 117.599 102.352 45.879  1.00 107.40 ? 88  ASN B C   1 
ATOM   6543  O O   . ASN B 1 68  ? 117.729 102.814 44.747  1.00 105.26 ? 88  ASN B O   1 
ATOM   6544  C CB  . ASN B 1 68  ? 115.462 101.093 45.428  1.00 118.50 ? 88  ASN B CB  1 
ATOM   6545  C CG  . ASN B 1 68  ? 115.479 100.936 43.921  1.00 123.60 ? 88  ASN B CG  1 
ATOM   6546  O OD1 . ASN B 1 68  ? 116.532 100.748 43.314  1.00 125.25 ? 88  ASN B OD1 1 
ATOM   6547  N ND2 . ASN B 1 68  ? 114.312 101.004 43.304  1.00 124.72 ? 88  ASN B ND2 1 
ATOM   6548  N N   . ILE B 1 69  ? 118.105 102.951 46.965  1.00 104.03 ? 89  ILE B N   1 
ATOM   6549  C CA  . ILE B 1 69  ? 118.929 104.148 46.866  1.00 102.15 ? 89  ILE B CA  1 
ATOM   6550  C C   . ILE B 1 69  ? 120.145 103.976 47.771  1.00 97.48  ? 89  ILE B C   1 
ATOM   6551  O O   . ILE B 1 69  ? 120.031 103.434 48.867  1.00 97.74  ? 89  ILE B O   1 
ATOM   6552  C CB  . ILE B 1 69  ? 118.137 105.427 47.213  1.00 103.29 ? 89  ILE B CB  1 
ATOM   6553  C CG1 . ILE B 1 69  ? 117.621 105.422 48.655  1.00 100.19 ? 89  ILE B CG1 1 
ATOM   6554  C CG2 . ILE B 1 69  ? 117.012 105.662 46.217  1.00 106.38 ? 89  ILE B CG2 1 
ATOM   6555  C CD1 . ILE B 1 69  ? 118.435 106.261 49.606  1.00 99.05  ? 89  ILE B CD1 1 
ATOM   6556  N N   . THR B 1 70  ? 121.303 104.450 47.299  1.00 91.65  ? 90  THR B N   1 
ATOM   6557  C CA  . THR B 1 70  ? 122.555 104.289 48.022  1.00 87.35  ? 90  THR B CA  1 
ATOM   6558  C C   . THR B 1 70  ? 122.809 105.516 48.893  1.00 80.51  ? 90  THR B C   1 
ATOM   6559  O O   . THR B 1 70  ? 122.320 106.604 48.605  1.00 79.41  ? 90  THR B O   1 
ATOM   6560  C CB  . THR B 1 70  ? 123.728 104.042 47.065  1.00 89.34  ? 90  THR B CB  1 
ATOM   6561  O OG1 . THR B 1 70  ? 123.869 105.184 46.220  1.00 89.14  ? 90  THR B OG1 1 
ATOM   6562  C CG2 . THR B 1 70  ? 123.544 102.799 46.222  1.00 91.00  ? 90  THR B CG2 1 
ATOM   6563  N N   . LEU B 1 71  ? 123.595 105.309 49.953  1.00 73.91  ? 91  LEU B N   1 
ATOM   6564  C CA  . LEU B 1 71  ? 123.978 106.360 50.878  1.00 68.10  ? 91  LEU B CA  1 
ATOM   6565  C C   . LEU B 1 71  ? 125.491 106.549 50.819  1.00 64.80  ? 91  LEU B C   1 
ATOM   6566  O O   . LEU B 1 71  ? 126.244 105.669 51.223  1.00 64.37  ? 91  LEU B O   1 
ATOM   6567  C CB  . LEU B 1 71  ? 123.518 105.969 52.286  1.00 67.12  ? 91  LEU B CB  1 
ATOM   6568  C CG  . LEU B 1 71  ? 122.437 106.848 52.907  1.00 68.23  ? 91  LEU B CG  1 
ATOM   6569  C CD1 . LEU B 1 71  ? 122.020 106.304 54.266  1.00 68.68  ? 91  LEU B CD1 1 
ATOM   6570  C CD2 . LEU B 1 71  ? 122.924 108.285 53.037  1.00 68.95  ? 91  LEU B CD2 1 
ATOM   6571  N N   . GLY B 1 72  ? 125.922 107.703 50.297  1.00 62.13  ? 92  GLY B N   1 
ATOM   6572  C CA  . GLY B 1 72  ? 127.328 108.059 50.238  1.00 59.95  ? 92  GLY B CA  1 
ATOM   6573  C C   . GLY B 1 72  ? 127.764 108.848 51.470  1.00 56.92  ? 92  GLY B C   1 
ATOM   6574  O O   . GLY B 1 72  ? 126.951 109.136 52.341  1.00 56.38  ? 92  GLY B O   1 
ATOM   6575  N N   . CYS B 1 73  ? 129.060 109.164 51.544  1.00 54.30  ? 93  CYS B N   1 
ATOM   6576  C CA  . CYS B 1 73  ? 129.565 109.977 52.635  1.00 52.88  ? 93  CYS B CA  1 
ATOM   6577  C C   . CYS B 1 73  ? 130.665 110.914 52.153  1.00 50.25  ? 93  CYS B C   1 
ATOM   6578  O O   . CYS B 1 73  ? 131.304 110.666 51.131  1.00 51.55  ? 93  CYS B O   1 
ATOM   6579  C CB  . CYS B 1 73  ? 130.084 109.129 53.791  1.00 54.89  ? 93  CYS B CB  1 
ATOM   6580  S SG  . CYS B 1 73  ? 131.417 107.991 53.331  1.00 60.58  ? 93  CYS B SG  1 
ATOM   6581  N N   . GLU B 1 74  ? 130.853 111.995 52.921  1.00 47.05  ? 94  GLU B N   1 
ATOM   6582  C CA  . GLU B 1 74  ? 131.983 112.895 52.781  1.00 45.33  ? 94  GLU B CA  1 
ATOM   6583  C C   . GLU B 1 74  ? 132.561 113.136 54.172  1.00 41.73  ? 94  GLU B C   1 
ATOM   6584  O O   . GLU B 1 74  ? 131.977 113.870 54.965  1.00 41.10  ? 94  GLU B O   1 
ATOM   6585  C CB  . GLU B 1 74  ? 131.529 114.186 52.100  1.00 47.51  ? 94  GLU B CB  1 
ATOM   6586  C CG  . GLU B 1 74  ? 132.608 115.243 51.969  1.00 50.14  ? 94  GLU B CG  1 
ATOM   6587  C CD  . GLU B 1 74  ? 132.417 116.160 50.771  1.00 53.62  ? 94  GLU B CD  1 
ATOM   6588  O OE1 . GLU B 1 74  ? 131.941 117.299 50.960  1.00 54.99  ? 94  GLU B OE1 1 
ATOM   6589  O OE2 . GLU B 1 74  ? 132.741 115.724 49.645  1.00 54.90  ? 94  GLU B OE2 1 
ATOM   6590  N N   . ILE B 1 75  ? 133.679 112.468 54.474  1.00 38.79  ? 95  ILE B N   1 
ATOM   6591  C CA  . ILE B 1 75  ? 134.246 112.498 55.814  1.00 36.03  ? 95  ILE B CA  1 
ATOM   6592  C C   . ILE B 1 75  ? 135.390 113.502 55.832  1.00 34.73  ? 95  ILE B C   1 
ATOM   6593  O O   . ILE B 1 75  ? 136.260 113.461 54.966  1.00 36.04  ? 95  ILE B O   1 
ATOM   6594  C CB  . ILE B 1 75  ? 134.711 111.100 56.263  1.00 35.42  ? 95  ILE B CB  1 
ATOM   6595  C CG1 . ILE B 1 75  ? 133.561 110.088 56.230  1.00 35.98  ? 95  ILE B CG1 1 
ATOM   6596  C CG2 . ILE B 1 75  ? 135.364 111.181 57.636  1.00 34.75  ? 95  ILE B CG2 1 
ATOM   6597  C CD1 . ILE B 1 75  ? 133.988 108.658 56.429  1.00 36.29  ? 95  ILE B CD1 1 
ATOM   6598  N N   . ARG B 1 76  ? 135.385 114.387 56.834  1.00 33.20  ? 96  ARG B N   1 
ATOM   6599  C CA  . ARG B 1 76  ? 136.416 115.403 56.957  1.00 32.25  ? 96  ARG B CA  1 
ATOM   6600  C C   . ARG B 1 76  ? 137.045 115.350 58.344  1.00 31.12  ? 96  ARG B C   1 
ATOM   6601  O O   . ARG B 1 76  ? 136.514 114.730 59.263  1.00 31.21  ? 96  ARG B O   1 
ATOM   6602  C CB  . ARG B 1 76  ? 135.832 116.784 56.655  1.00 32.73  ? 96  ARG B CB  1 
ATOM   6603  C CG  . ARG B 1 76  ? 135.450 116.952 55.194  1.00 33.41  ? 96  ARG B CG  1 
ATOM   6604  C CD  . ARG B 1 76  ? 134.872 118.320 54.901  1.00 33.92  ? 96  ARG B CD  1 
ATOM   6605  N NE  . ARG B 1 76  ? 134.537 118.455 53.489  1.00 34.53  ? 96  ARG B NE  1 
ATOM   6606  C CZ  . ARG B 1 76  ? 135.386 118.809 52.528  1.00 35.47  ? 96  ARG B CZ  1 
ATOM   6607  N NH1 . ARG B 1 76  ? 136.644 119.096 52.817  1.00 35.87  ? 96  ARG B NH1 1 
ATOM   6608  N NH2 . ARG B 1 76  ? 134.968 118.878 51.275  1.00 35.64  ? 96  ARG B NH2 1 
ATOM   6609  N N   . ASP B 1 77  ? 138.192 116.017 58.457  1.00 30.12  ? 97  ASP B N   1 
ATOM   6610  C CA  . ASP B 1 77  ? 138.993 115.997 59.663  1.00 29.62  ? 97  ASP B CA  1 
ATOM   6611  C C   . ASP B 1 77  ? 138.817 117.321 60.398  1.00 28.94  ? 97  ASP B C   1 
ATOM   6612  O O   . ASP B 1 77  ? 139.077 118.376 59.825  1.00 29.30  ? 97  ASP B O   1 
ATOM   6613  C CB  . ASP B 1 77  ? 140.461 115.776 59.308  1.00 30.10  ? 97  ASP B CB  1 
ATOM   6614  C CG  . ASP B 1 77  ? 141.387 115.821 60.509  1.00 30.31  ? 97  ASP B CG  1 
ATOM   6615  O OD1 . ASP B 1 77  ? 140.871 115.796 61.649  1.00 30.52  ? 97  ASP B OD1 1 
ATOM   6616  O OD2 . ASP B 1 77  ? 142.612 115.832 60.308  1.00 30.35  ? 97  ASP B OD2 1 
ATOM   6617  N N   . SER B 1 78  ? 138.375 117.259 61.660  1.00 28.44  ? 98  SER B N   1 
ATOM   6618  C CA  . SER B 1 78  ? 138.200 118.455 62.467  1.00 28.37  ? 98  SER B CA  1 
ATOM   6619  C C   . SER B 1 78  ? 139.442 118.746 63.309  1.00 29.27  ? 98  SER B C   1 
ATOM   6620  O O   . SER B 1 78  ? 139.547 119.828 63.879  1.00 29.87  ? 98  SER B O   1 
ATOM   6621  C CB  . SER B 1 78  ? 136.973 118.350 63.332  1.00 27.96  ? 98  SER B CB  1 
ATOM   6622  O OG  . SER B 1 78  ? 137.092 117.289 64.266  1.00 27.62  ? 98  SER B OG  1 
ATOM   6623  N N   . CYS B 1 79  ? 140.363 117.778 63.408  1.00 29.99  ? 99  CYS B N   1 
ATOM   6624  C CA  . CYS B 1 79  ? 141.579 117.917 64.199  1.00 30.81  ? 99  CYS B CA  1 
ATOM   6625  C C   . CYS B 1 79  ? 141.268 118.383 65.622  1.00 29.18  ? 99  CYS B C   1 
ATOM   6626  O O   . CYS B 1 79  ? 142.127 118.971 66.276  1.00 29.81  ? 99  CYS B O   1 
ATOM   6627  C CB  . CYS B 1 79  ? 142.561 118.892 63.558  1.00 33.64  ? 99  CYS B CB  1 
ATOM   6628  S SG  . CYS B 1 79  ? 142.914 118.543 61.813  1.00 39.39  ? 99  CYS B SG  1 
ATOM   6629  N N   . TRP B 1 80  ? 140.049 118.104 66.100  1.00 27.95  ? 100 TRP B N   1 
ATOM   6630  C CA  . TRP B 1 80  ? 139.622 118.464 67.444  1.00 27.40  ? 100 TRP B CA  1 
ATOM   6631  C C   . TRP B 1 80  ? 139.804 119.957 67.699  1.00 27.00  ? 100 TRP B C   1 
ATOM   6632  O O   . TRP B 1 80  ? 140.148 120.365 68.804  1.00 27.22  ? 100 TRP B O   1 
ATOM   6633  C CB  . TRP B 1 80  ? 140.379 117.624 68.476  1.00 27.57  ? 100 TRP B CB  1 
ATOM   6634  C CG  . TRP B 1 80  ? 139.693 117.536 69.802  1.00 27.90  ? 100 TRP B CG  1 
ATOM   6635  C CD1 . TRP B 1 80  ? 139.777 118.407 70.849  1.00 28.20  ? 100 TRP B CD1 1 
ATOM   6636  C CD2 . TRP B 1 80  ? 138.769 116.515 70.207  1.00 27.84  ? 100 TRP B CD2 1 
ATOM   6637  N NE1 . TRP B 1 80  ? 138.989 117.982 71.884  1.00 28.29  ? 100 TRP B NE1 1 
ATOM   6638  C CE2 . TRP B 1 80  ? 138.366 116.818 71.521  1.00 28.09  ? 100 TRP B CE2 1 
ATOM   6639  C CE3 . TRP B 1 80  ? 138.266 115.366 69.592  1.00 27.73  ? 100 TRP B CE3 1 
ATOM   6640  C CZ2 . TRP B 1 80  ? 137.457 116.025 72.217  1.00 28.37  ? 100 TRP B CZ2 1 
ATOM   6641  C CZ3 . TRP B 1 80  ? 137.379 114.575 70.283  1.00 28.07  ? 100 TRP B CZ3 1 
ATOM   6642  C CH2 . TRP B 1 80  ? 136.985 114.901 71.578  1.00 28.55  ? 100 TRP B CH2 1 
ATOM   6643  N N   . HIS B 1 81  ? 139.556 120.774 66.675  1.00 27.03  ? 101 HIS B N   1 
ATOM   6644  C CA  . HIS B 1 81  ? 139.742 122.208 66.795  1.00 27.40  ? 101 HIS B CA  1 
ATOM   6645  C C   . HIS B 1 81  ? 138.534 122.902 66.184  1.00 27.29  ? 101 HIS B C   1 
ATOM   6646  O O   . HIS B 1 81  ? 138.021 122.458 65.162  1.00 27.24  ? 101 HIS B O   1 
ATOM   6647  C CB  . HIS B 1 81  ? 141.044 122.636 66.114  1.00 28.04  ? 101 HIS B CB  1 
ATOM   6648  C CG  . HIS B 1 81  ? 141.495 124.002 66.493  1.00 28.64  ? 101 HIS B CG  1 
ATOM   6649  N ND1 . HIS B 1 81  ? 141.714 125.005 65.576  1.00 28.89  ? 101 HIS B ND1 1 
ATOM   6650  C CD2 . HIS B 1 81  ? 141.781 124.524 67.690  1.00 29.10  ? 101 HIS B CD2 1 
ATOM   6651  C CE1 . HIS B 1 81  ? 142.115 126.097 66.211  1.00 29.35  ? 101 HIS B CE1 1 
ATOM   6652  N NE2 . HIS B 1 81  ? 142.162 125.828 67.496  1.00 29.47  ? 101 HIS B NE2 1 
ATOM   6653  N N   . SER B 1 82  ? 138.098 123.993 66.822  1.00 27.08  ? 102 SER B N   1 
ATOM   6654  C CA  . SER B 1 82  ? 136.894 124.696 66.418  1.00 27.04  ? 102 SER B CA  1 
ATOM   6655  C C   . SER B 1 82  ? 137.075 125.340 65.045  1.00 27.32  ? 102 SER B C   1 
ATOM   6656  O O   . SER B 1 82  ? 136.141 125.349 64.245  1.00 28.14  ? 102 SER B O   1 
ATOM   6657  C CB  . SER B 1 82  ? 136.505 125.712 67.455  1.00 27.26  ? 102 SER B CB  1 
ATOM   6658  O OG  . SER B 1 82  ? 136.342 125.103 68.728  1.00 27.23  ? 102 SER B OG  1 
ATOM   6659  N N   . ALA B 1 83  ? 138.275 125.869 64.776  1.00 27.26  ? 103 ALA B N   1 
ATOM   6660  C CA  . ALA B 1 83  ? 138.533 126.601 63.547  1.00 27.72  ? 103 ALA B CA  1 
ATOM   6661  C C   . ALA B 1 83  ? 138.605 125.644 62.361  1.00 27.68  ? 103 ALA B C   1 
ATOM   6662  O O   . ALA B 1 83  ? 138.047 125.919 61.299  1.00 27.90  ? 103 ALA B O   1 
ATOM   6663  C CB  . ALA B 1 83  ? 139.802 127.402 63.680  1.00 28.44  ? 103 ALA B CB  1 
ATOM   6664  N N   . VAL B 1 84  ? 139.297 124.517 62.551  1.00 28.16  ? 104 VAL B N   1 
ATOM   6665  C CA  . VAL B 1 84  ? 139.437 123.526 61.499  1.00 28.76  ? 104 VAL B CA  1 
ATOM   6666  C C   . VAL B 1 84  ? 138.058 122.948 61.185  1.00 29.09  ? 104 VAL B C   1 
ATOM   6667  O O   . VAL B 1 84  ? 137.712 122.759 60.022  1.00 29.85  ? 104 VAL B O   1 
ATOM   6668  C CB  . VAL B 1 84  ? 140.441 122.422 61.875  1.00 28.89  ? 104 VAL B CB  1 
ATOM   6669  C CG1 . VAL B 1 84  ? 140.654 121.458 60.721  1.00 29.22  ? 104 VAL B CG1 1 
ATOM   6670  C CG2 . VAL B 1 84  ? 141.773 122.991 62.333  1.00 28.98  ? 104 VAL B CG2 1 
ATOM   6671  N N   . ALA B 1 85  ? 137.270 122.684 62.232  1.00 28.88  ? 105 ALA B N   1 
ATOM   6672  C CA  . ALA B 1 85  ? 135.934 122.142 62.055  1.00 28.95  ? 105 ALA B CA  1 
ATOM   6673  C C   . ALA B 1 85  ? 135.056 123.143 61.312  1.00 29.85  ? 105 ALA B C   1 
ATOM   6674  O O   . ALA B 1 85  ? 134.242 122.748 60.481  1.00 30.27  ? 105 ALA B O   1 
ATOM   6675  C CB  . ALA B 1 85  ? 135.335 121.786 63.386  1.00 28.72  ? 105 ALA B CB  1 
ATOM   6676  N N   . LEU B 1 86  ? 135.225 124.435 61.617  1.00 30.96  ? 106 LEU B N   1 
ATOM   6677  C CA  . LEU B 1 86  ? 134.402 125.461 61.001  1.00 31.81  ? 106 LEU B CA  1 
ATOM   6678  C C   . LEU B 1 86  ? 134.725 125.553 59.511  1.00 33.06  ? 106 LEU B C   1 
ATOM   6679  O O   . LEU B 1 86  ? 133.815 125.685 58.700  1.00 33.66  ? 106 LEU B O   1 
ATOM   6680  C CB  . LEU B 1 86  ? 134.615 126.797 61.717  1.00 31.94  ? 106 LEU B CB  1 
ATOM   6681  C CG  . LEU B 1 86  ? 133.703 127.942 61.274  1.00 32.61  ? 106 LEU B CG  1 
ATOM   6682  C CD1 . LEU B 1 86  ? 132.238 127.622 61.538  1.00 32.84  ? 106 LEU B CD1 1 
ATOM   6683  C CD2 . LEU B 1 86  ? 134.090 129.235 61.975  1.00 33.04  ? 106 LEU B CD2 1 
ATOM   6684  N N   . GLU B 1 87  ? 136.008 125.456 59.146  1.00 34.61  ? 107 GLU B N   1 
ATOM   6685  C CA  . GLU B 1 87  ? 136.374 125.551 57.742  1.00 36.65  ? 107 GLU B CA  1 
ATOM   6686  C C   . GLU B 1 87  ? 135.893 124.304 56.995  1.00 36.83  ? 107 GLU B C   1 
ATOM   6687  O O   . GLU B 1 87  ? 135.429 124.420 55.865  1.00 38.00  ? 107 GLU B O   1 
ATOM   6688  C CB  . GLU B 1 87  ? 137.862 125.855 57.557  1.00 38.78  ? 107 GLU B CB  1 
ATOM   6689  C CG  . GLU B 1 87  ? 138.815 124.836 58.139  1.00 41.35  ? 107 GLU B CG  1 
ATOM   6690  C CD  . GLU B 1 87  ? 140.266 125.070 57.754  1.00 44.26  ? 107 GLU B CD  1 
ATOM   6691  O OE1 . GLU B 1 87  ? 140.546 125.184 56.540  1.00 45.47  ? 107 GLU B OE1 1 
ATOM   6692  O OE2 . GLU B 1 87  ? 141.112 125.142 58.669  1.00 45.70  ? 107 GLU B OE2 1 
ATOM   6693  N N   . GLN B 1 88  ? 135.954 123.130 57.631  1.00 36.31  ? 108 GLN B N   1 
ATOM   6694  C CA  . GLN B 1 88  ? 135.461 121.911 57.005  1.00 36.06  ? 108 GLN B CA  1 
ATOM   6695  C C   . GLN B 1 88  ? 133.940 121.971 56.847  1.00 36.35  ? 108 GLN B C   1 
ATOM   6696  O O   . GLN B 1 88  ? 133.398 121.466 55.867  1.00 37.48  ? 108 GLN B O   1 
ATOM   6697  C CB  . GLN B 1 88  ? 135.878 120.677 57.806  1.00 36.01  ? 108 GLN B CB  1 
ATOM   6698  C CG  . GLN B 1 88  ? 137.385 120.497 57.917  1.00 35.91  ? 108 GLN B CG  1 
ATOM   6699  C CD  . GLN B 1 88  ? 138.070 120.441 56.574  1.00 35.95  ? 108 GLN B CD  1 
ATOM   6700  O OE1 . GLN B 1 88  ? 137.925 119.486 55.813  1.00 35.67  ? 108 GLN B OE1 1 
ATOM   6701  N NE2 . GLN B 1 88  ? 138.840 121.473 56.272  1.00 36.45  ? 108 GLN B NE2 1 
ATOM   6702  N N   . SER B 1 89  ? 133.244 122.591 57.805  1.00 35.84  ? 109 SER B N   1 
ATOM   6703  C CA  . SER B 1 89  ? 131.800 122.738 57.707  1.00 35.85  ? 109 SER B CA  1 
ATOM   6704  C C   . SER B 1 89  ? 131.440 123.707 56.581  1.00 36.87  ? 109 SER B C   1 
ATOM   6705  O O   . SER B 1 89  ? 130.426 123.534 55.905  1.00 37.66  ? 109 SER B O   1 
ATOM   6706  C CB  . SER B 1 89  ? 131.216 123.169 59.021  1.00 35.35  ? 109 SER B CB  1 
ATOM   6707  O OG  . SER B 1 89  ? 131.653 122.315 60.066  1.00 34.95  ? 109 SER B OG  1 
ATOM   6708  N N   . ILE B 1 90  ? 132.276 124.731 56.383  1.00 38.23  ? 110 ILE B N   1 
ATOM   6709  C CA  . ILE B 1 90  ? 132.102 125.641 55.263  1.00 39.91  ? 110 ILE B CA  1 
ATOM   6710  C C   . ILE B 1 90  ? 132.244 124.854 53.963  1.00 43.10  ? 110 ILE B C   1 
ATOM   6711  O O   . ILE B 1 90  ? 131.507 125.103 53.016  1.00 44.88  ? 110 ILE B O   1 
ATOM   6712  C CB  . ILE B 1 90  ? 133.080 126.830 55.348  1.00 39.37  ? 110 ILE B CB  1 
ATOM   6713  C CG1 . ILE B 1 90  ? 132.594 127.866 56.365  1.00 39.09  ? 110 ILE B CG1 1 
ATOM   6714  C CG2 . ILE B 1 90  ? 133.306 127.456 53.979  1.00 39.50  ? 110 ILE B CG2 1 
ATOM   6715  C CD1 . ILE B 1 90  ? 133.611 128.932 56.690  1.00 39.07  ? 110 ILE B CD1 1 
ATOM   6716  N N   . GLU B 1 91  ? 133.184 123.903 53.927  1.00 46.43  ? 111 GLU B N   1 
ATOM   6717  C CA  . GLU B 1 91  ? 133.361 123.036 52.773  1.00 49.01  ? 111 GLU B CA  1 
ATOM   6718  C C   . GLU B 1 91  ? 132.123 122.163 52.566  1.00 48.84  ? 111 GLU B C   1 
ATOM   6719  O O   . GLU B 1 91  ? 131.776 121.862 51.426  1.00 49.31  ? 111 GLU B O   1 
ATOM   6720  C CB  . GLU B 1 91  ? 134.614 122.168 52.924  1.00 51.69  ? 111 GLU B CB  1 
ATOM   6721  C CG  . GLU B 1 91  ? 135.912 122.954 53.016  1.00 55.02  ? 111 GLU B CG  1 
ATOM   6722  C CD  . GLU B 1 91  ? 136.164 123.889 51.848  1.00 58.75  ? 111 GLU B CD  1 
ATOM   6723  O OE1 . GLU B 1 91  ? 135.809 123.492 50.722  1.00 60.12  ? 111 GLU B OE1 1 
ATOM   6724  O OE2 . GLU B 1 91  ? 136.711 124.994 52.072  1.00 60.65  ? 111 GLU B OE2 1 
ATOM   6725  N N   . PHE B 1 92  ? 131.465 121.756 53.660  1.00 49.34  ? 112 PHE B N   1 
ATOM   6726  C CA  . PHE B 1 92  ? 130.215 121.015 53.567  1.00 50.90  ? 112 PHE B CA  1 
ATOM   6727  C C   . PHE B 1 92  ? 129.139 121.858 52.887  1.00 55.20  ? 112 PHE B C   1 
ATOM   6728  O O   . PHE B 1 92  ? 128.493 121.397 51.948  1.00 56.24  ? 112 PHE B O   1 
ATOM   6729  C CB  . PHE B 1 92  ? 129.741 120.553 54.950  1.00 49.08  ? 112 PHE B CB  1 
ATOM   6730  C CG  . PHE B 1 92  ? 130.387 119.293 55.468  1.00 47.18  ? 112 PHE B CG  1 
ATOM   6731  C CD1 . PHE B 1 92  ? 130.928 118.360 54.599  1.00 46.45  ? 112 PHE B CD1 1 
ATOM   6732  C CD2 . PHE B 1 92  ? 130.460 119.040 56.830  1.00 45.85  ? 112 PHE B CD2 1 
ATOM   6733  C CE1 . PHE B 1 92  ? 131.520 117.203 55.078  1.00 46.06  ? 112 PHE B CE1 1 
ATOM   6734  C CE2 . PHE B 1 92  ? 131.057 117.882 57.310  1.00 45.50  ? 112 PHE B CE2 1 
ATOM   6735  C CZ  . PHE B 1 92  ? 131.587 116.967 56.432  1.00 45.75  ? 112 PHE B CZ  1 
ATOM   6736  N N   . ILE B 1 93  ? 128.973 123.103 53.350  1.00 59.91  ? 113 ILE B N   1 
ATOM   6737  C CA  . ILE B 1 93  ? 127.849 123.930 52.940  1.00 63.65  ? 113 ILE B CA  1 
ATOM   6738  C C   . ILE B 1 93  ? 128.139 124.648 51.622  1.00 69.49  ? 113 ILE B C   1 
ATOM   6739  O O   . ILE B 1 93  ? 127.240 125.290 51.095  1.00 71.63  ? 113 ILE B O   1 
ATOM   6740  C CB  . ILE B 1 93  ? 127.499 124.969 54.021  1.00 62.60  ? 113 ILE B CB  1 
ATOM   6741  C CG1 . ILE B 1 93  ? 128.563 126.066 54.089  1.00 63.27  ? 113 ILE B CG1 1 
ATOM   6742  C CG2 . ILE B 1 93  ? 127.272 124.309 55.372  1.00 61.83  ? 113 ILE B CG2 1 
ATOM   6743  C CD1 . ILE B 1 93  ? 128.037 127.402 54.538  1.00 63.62  ? 113 ILE B CD1 1 
ATOM   6744  N N   . ARG B 1 94  ? 129.384 124.585 51.128  1.00 76.33  ? 114 ARG B N   1 
ATOM   6745  C CA  . ARG B 1 94  ? 129.791 125.333 49.946  1.00 83.91  ? 114 ARG B CA  1 
ATOM   6746  C C   . ARG B 1 94  ? 128.877 124.999 48.768  1.00 91.58  ? 114 ARG B C   1 
ATOM   6747  O O   . ARG B 1 94  ? 128.560 125.871 47.958  1.00 93.69  ? 114 ARG B O   1 
ATOM   6748  C CB  . ARG B 1 94  ? 131.251 125.031 49.585  1.00 85.17  ? 114 ARG B CB  1 
ATOM   6749  C CG  . ARG B 1 94  ? 131.812 125.891 48.458  1.00 87.14  ? 114 ARG B CG  1 
ATOM   6750  C CD  . ARG B 1 94  ? 133.149 125.390 47.949  1.00 88.94  ? 114 ARG B CD  1 
ATOM   6751  N NE  . ARG B 1 94  ? 134.217 125.618 48.913  1.00 90.69  ? 114 ARG B NE  1 
ATOM   6752  C CZ  . ARG B 1 94  ? 135.221 126.481 48.762  1.00 93.34  ? 114 ARG B CZ  1 
ATOM   6753  N NH1 . ARG B 1 94  ? 135.305 127.239 47.681  1.00 94.88  ? 114 ARG B NH1 1 
ATOM   6754  N NH2 . ARG B 1 94  ? 136.144 126.589 49.705  1.00 92.69  ? 114 ARG B NH2 1 
ATOM   6755  N N   . ASP B 1 95  ? 128.456 123.728 48.683  1.00 98.60  ? 115 ASP B N   1 
ATOM   6756  C CA  . ASP B 1 95  ? 127.673 123.265 47.551  1.00 105.55 ? 115 ASP B CA  1 
ATOM   6757  C C   . ASP B 1 95  ? 126.286 123.904 47.576  1.00 107.79 ? 115 ASP B C   1 
ATOM   6758  O O   . ASP B 1 95  ? 125.733 124.204 46.522  1.00 107.54 ? 115 ASP B O   1 
ATOM   6759  C CB  . ASP B 1 95  ? 127.579 121.741 47.532  1.00 109.28 ? 115 ASP B CB  1 
ATOM   6760  C CG  . ASP B 1 95  ? 126.822 121.144 48.704  1.00 111.73 ? 115 ASP B CG  1 
ATOM   6761  O OD1 . ASP B 1 95  ? 126.490 121.872 49.666  1.00 111.19 ? 115 ASP B OD1 1 
ATOM   6762  O OD2 . ASP B 1 95  ? 126.561 119.943 48.635  1.00 111.42 ? 115 ASP B OD2 1 
ATOM   6763  N N   . SER B 1 96  ? 125.734 124.112 48.779  1.00 109.31 ? 116 SER B N   1 
ATOM   6764  C CA  . SER B 1 96  ? 124.403 124.684 48.923  1.00 111.28 ? 116 SER B CA  1 
ATOM   6765  C C   . SER B 1 96  ? 124.385 126.141 48.458  1.00 112.38 ? 116 SER B C   1 
ATOM   6766  O O   . SER B 1 96  ? 123.372 126.606 47.940  1.00 113.52 ? 116 SER B O   1 
ATOM   6767  C CB  . SER B 1 96  ? 123.903 124.561 50.338  1.00 111.78 ? 116 SER B CB  1 
ATOM   6768  O OG  . SER B 1 96  ? 122.515 124.862 50.403  1.00 111.20 ? 116 SER B OG  1 
ATOM   6769  N N   . LEU B 1 97  ? 125.504 126.854 48.650  1.00 113.07 ? 117 LEU B N   1 
ATOM   6770  C CA  . LEU B 1 97  ? 125.614 128.245 48.236  1.00 115.35 ? 117 LEU B CA  1 
ATOM   6771  C C   . LEU B 1 97  ? 125.721 128.322 46.707  1.00 116.67 ? 117 LEU B C   1 
ATOM   6772  O O   . LEU B 1 97  ? 126.627 127.663 46.159  1.00 116.46 ? 117 LEU B O   1 
ATOM   6773  C CB  . LEU B 1 97  ? 126.835 128.877 48.917  1.00 114.43 ? 117 LEU B CB  1 
ATOM   6774  C CG  . LEU B 1 97  ? 126.686 129.146 50.416  1.00 112.30 ? 117 LEU B CG  1 
ATOM   6775  C CD1 . LEU B 1 97  ? 127.984 129.673 51.011  1.00 111.36 ? 117 LEU B CD1 1 
ATOM   6776  C CD2 . LEU B 1 97  ? 125.548 130.119 50.676  1.00 111.79 ? 117 LEU B CD2 1 
ATOM   6777  N N   . LYS B 1 121 ? 126.232 117.967 45.022  1.00 86.33  ? 141 LYS B N   1 
ATOM   6778  C CA  . LYS B 1 121 ? 125.136 117.199 45.674  1.00 85.78  ? 141 LYS B CA  1 
ATOM   6779  C C   . LYS B 1 121 ? 125.094 117.560 47.156  1.00 79.96  ? 141 LYS B C   1 
ATOM   6780  O O   . LYS B 1 121 ? 126.118 117.504 47.835  1.00 79.65  ? 141 LYS B O   1 
ATOM   6781  C CB  . LYS B 1 121 ? 125.343 115.693 45.491  1.00 89.82  ? 141 LYS B CB  1 
ATOM   6782  C CG  . LYS B 1 121 ? 125.520 115.236 44.048  1.00 94.02  ? 141 LYS B CG  1 
ATOM   6783  C CD  . LYS B 1 121 ? 125.597 113.732 43.881  1.00 97.04  ? 141 LYS B CD  1 
ATOM   6784  C CE  . LYS B 1 121 ? 124.274 113.036 44.129  1.00 98.57  ? 141 LYS B CE  1 
ATOM   6785  N NZ  . LYS B 1 121 ? 124.363 111.579 43.875  1.00 98.88  ? 141 LYS B NZ  1 
ATOM   6786  N N   . PRO B 1 122 ? 123.913 117.929 47.700  1.00 73.27  ? 142 PRO B N   1 
ATOM   6787  C CA  . PRO B 1 122 ? 123.828 118.520 49.035  1.00 68.80  ? 142 PRO B CA  1 
ATOM   6788  C C   . PRO B 1 122 ? 124.166 117.537 50.152  1.00 61.90  ? 142 PRO B C   1 
ATOM   6789  O O   . PRO B 1 122 ? 123.835 116.356 50.063  1.00 60.83  ? 142 PRO B O   1 
ATOM   6790  C CB  . PRO B 1 122 ? 122.364 118.979 49.127  1.00 71.03  ? 142 PRO B CB  1 
ATOM   6791  C CG  . PRO B 1 122 ? 121.622 118.042 48.197  1.00 72.22  ? 142 PRO B CG  1 
ATOM   6792  C CD  . PRO B 1 122 ? 122.594 117.775 47.066  1.00 73.03  ? 142 PRO B CD  1 
ATOM   6793  N N   . ILE B 1 123 ? 124.830 118.050 51.195  1.00 55.68  ? 143 ILE B N   1 
ATOM   6794  C CA  . ILE B 1 123 ? 125.077 117.293 52.411  1.00 51.42  ? 143 ILE B CA  1 
ATOM   6795  C C   . ILE B 1 123 ? 123.822 117.372 53.273  1.00 48.03  ? 143 ILE B C   1 
ATOM   6796  O O   . ILE B 1 123 ? 123.519 118.424 53.829  1.00 48.46  ? 143 ILE B O   1 
ATOM   6797  C CB  . ILE B 1 123 ? 126.302 117.829 53.175  1.00 51.98  ? 143 ILE B CB  1 
ATOM   6798  C CG1 . ILE B 1 123 ? 127.570 117.827 52.316  1.00 53.38  ? 143 ILE B CG1 1 
ATOM   6799  C CG2 . ILE B 1 123 ? 126.486 117.064 54.481  1.00 51.43  ? 143 ILE B CG2 1 
ATOM   6800  C CD1 . ILE B 1 123 ? 128.087 116.456 51.956  1.00 53.68  ? 143 ILE B CD1 1 
ATOM   6801  N N   . VAL B 1 124 ? 123.104 116.253 53.381  1.00 44.85  ? 144 VAL B N   1 
ATOM   6802  C CA  . VAL B 1 124 ? 121.807 116.243 54.033  1.00 42.95  ? 144 VAL B CA  1 
ATOM   6803  C C   . VAL B 1 124 ? 121.984 116.383 55.542  1.00 40.08  ? 144 VAL B C   1 
ATOM   6804  O O   . VAL B 1 124 ? 121.181 117.041 56.199  1.00 40.02  ? 144 VAL B O   1 
ATOM   6805  C CB  . VAL B 1 124 ? 121.007 114.982 53.662  1.00 43.82  ? 144 VAL B CB  1 
ATOM   6806  C CG1 . VAL B 1 124 ? 120.699 114.970 52.176  1.00 44.70  ? 144 VAL B CG1 1 
ATOM   6807  C CG2 . VAL B 1 124 ? 121.702 113.693 54.084  1.00 43.90  ? 144 VAL B CG2 1 
ATOM   6808  N N   . GLY B 1 125 ? 123.042 115.767 56.076  1.00 36.54  ? 145 GLY B N   1 
ATOM   6809  C CA  . GLY B 1 125 ? 123.303 115.780 57.505  1.00 33.96  ? 145 GLY B CA  1 
ATOM   6810  C C   . GLY B 1 125 ? 124.766 115.462 57.790  1.00 31.77  ? 145 GLY B C   1 
ATOM   6811  O O   . GLY B 1 125 ? 125.463 114.916 56.931  1.00 32.34  ? 145 GLY B O   1 
ATOM   6812  N N   . VAL B 1 126 ? 125.206 115.774 59.014  1.00 29.42  ? 146 VAL B N   1 
ATOM   6813  C CA  . VAL B 1 126 ? 126.559 115.463 59.431  1.00 27.82  ? 146 VAL B CA  1 
ATOM   6814  C C   . VAL B 1 126 ? 126.502 114.671 60.732  1.00 26.05  ? 146 VAL B C   1 
ATOM   6815  O O   . VAL B 1 126 ? 125.587 114.842 61.535  1.00 25.89  ? 146 VAL B O   1 
ATOM   6816  C CB  . VAL B 1 126 ? 127.434 116.723 59.575  1.00 28.06  ? 146 VAL B CB  1 
ATOM   6817  C CG1 . VAL B 1 126 ? 127.234 117.692 58.419  1.00 28.20  ? 146 VAL B CG1 1 
ATOM   6818  C CG2 . VAL B 1 126 ? 127.206 117.414 60.903  1.00 28.26  ? 146 VAL B CG2 1 
ATOM   6819  N N   . ILE B 1 127 ? 127.486 113.790 60.910  1.00 24.68  ? 147 ILE B N   1 
ATOM   6820  C CA  . ILE B 1 127 ? 127.688 113.115 62.178  1.00 23.86  ? 147 ILE B CA  1 
ATOM   6821  C C   . ILE B 1 127 ? 128.616 113.983 63.020  1.00 23.51  ? 147 ILE B C   1 
ATOM   6822  O O   . ILE B 1 127 ? 129.821 114.019 62.796  1.00 23.33  ? 147 ILE B O   1 
ATOM   6823  C CB  . ILE B 1 127 ? 128.225 111.689 61.967  1.00 23.76  ? 147 ILE B CB  1 
ATOM   6824  C CG1 . ILE B 1 127 ? 127.354 110.905 60.983  1.00 23.73  ? 147 ILE B CG1 1 
ATOM   6825  C CG2 . ILE B 1 127 ? 128.347 110.966 63.294  1.00 23.81  ? 147 ILE B CG2 1 
ATOM   6826  C CD1 . ILE B 1 127 ? 125.903 110.771 61.408  1.00 23.75  ? 147 ILE B CD1 1 
ATOM   6827  N N   . GLY B 1 128 ? 128.017 114.670 63.997  1.00 23.56  ? 148 GLY B N   1 
ATOM   6828  C CA  . GLY B 1 128 ? 128.617 115.817 64.654  1.00 23.31  ? 148 GLY B CA  1 
ATOM   6829  C C   . GLY B 1 128 ? 129.985 115.510 65.249  1.00 23.16  ? 148 GLY B C   1 
ATOM   6830  O O   . GLY B 1 128 ? 130.282 114.368 65.593  1.00 23.55  ? 148 GLY B O   1 
ATOM   6831  N N   . PRO B 1 129 ? 130.850 116.534 65.399  1.00 22.55  ? 149 PRO B N   1 
ATOM   6832  C CA  . PRO B 1 129 ? 132.195 116.337 65.933  1.00 22.57  ? 149 PRO B CA  1 
ATOM   6833  C C   . PRO B 1 129 ? 132.182 115.890 67.393  1.00 22.74  ? 149 PRO B C   1 
ATOM   6834  O O   . PRO B 1 129 ? 131.155 115.952 68.065  1.00 22.77  ? 149 PRO B O   1 
ATOM   6835  C CB  . PRO B 1 129 ? 132.855 117.710 65.760  1.00 22.28  ? 149 PRO B CB  1 
ATOM   6836  C CG  . PRO B 1 129 ? 131.700 118.675 65.760  1.00 22.20  ? 149 PRO B CG  1 
ATOM   6837  C CD  . PRO B 1 129 ? 130.572 117.938 65.075  1.00 22.25  ? 149 PRO B CD  1 
ATOM   6838  N N   . GLY B 1 130 ? 133.342 115.423 67.857  1.00 22.75  ? 150 GLY B N   1 
ATOM   6839  C CA  . GLY B 1 130 ? 133.454 114.786 69.155  1.00 22.68  ? 150 GLY B CA  1 
ATOM   6840  C C   . GLY B 1 130 ? 133.270 115.772 70.303  1.00 22.34  ? 150 GLY B C   1 
ATOM   6841  O O   . GLY B 1 130 ? 132.533 115.496 71.246  1.00 22.87  ? 150 GLY B O   1 
ATOM   6842  N N   . SER B 1 131 ? 133.953 116.914 70.234  1.00 21.98  ? 151 SER B N   1 
ATOM   6843  C CA  . SER B 1 131 ? 133.939 117.834 71.357  1.00 22.24  ? 151 SER B CA  1 
ATOM   6844  C C   . SER B 1 131 ? 132.702 118.726 71.292  1.00 21.88  ? 151 SER B C   1 
ATOM   6845  O O   . SER B 1 131 ? 132.115 118.932 70.236  1.00 21.90  ? 151 SER B O   1 
ATOM   6846  C CB  . SER B 1 131 ? 135.199 118.643 71.446  1.00 22.94  ? 151 SER B CB  1 
ATOM   6847  O OG  . SER B 1 131 ? 135.286 119.584 70.397  1.00 23.21  ? 151 SER B OG  1 
ATOM   6848  N N   . SER B 1 132 ? 132.338 119.262 72.458  1.00 21.88  ? 152 SER B N   1 
ATOM   6849  C CA  . SER B 1 132 ? 131.131 120.046 72.615  1.00 22.09  ? 152 SER B CA  1 
ATOM   6850  C C   . SER B 1 132 ? 131.301 121.435 72.011  1.00 22.39  ? 152 SER B C   1 
ATOM   6851  O O   . SER B 1 132 ? 130.379 121.936 71.374  1.00 23.08  ? 152 SER B O   1 
ATOM   6852  C CB  . SER B 1 132 ? 130.755 120.133 74.062  1.00 22.40  ? 152 SER B CB  1 
ATOM   6853  O OG  . SER B 1 132 ? 130.432 118.844 74.557  1.00 22.66  ? 152 SER B OG  1 
ATOM   6854  N N   . SER B 1 133 ? 132.461 122.059 72.241  1.00 22.30  ? 153 SER B N   1 
ATOM   6855  C CA  . SER B 1 133 ? 132.703 123.413 71.770  1.00 22.43  ? 153 SER B CA  1 
ATOM   6856  C C   . SER B 1 133 ? 132.758 123.439 70.243  1.00 21.85  ? 153 SER B C   1 
ATOM   6857  O O   . SER B 1 133 ? 132.187 124.322 69.599  1.00 22.05  ? 153 SER B O   1 
ATOM   6858  C CB  . SER B 1 133 ? 133.960 123.975 72.386  1.00 22.90  ? 153 SER B CB  1 
ATOM   6859  O OG  . SER B 1 133 ? 135.043 123.065 72.256  1.00 23.01  ? 153 SER B OG  1 
ATOM   6860  N N   . VAL B 1 134 ? 133.441 122.443 69.676  1.00 21.17  ? 154 VAL B N   1 
ATOM   6861  C CA  . VAL B 1 134 ? 133.531 122.293 68.236  1.00 20.83  ? 154 VAL B CA  1 
ATOM   6862  C C   . VAL B 1 134 ? 132.134 122.053 67.671  1.00 20.60  ? 154 VAL B C   1 
ATOM   6863  O O   . VAL B 1 134 ? 131.788 122.614 66.634  1.00 20.66  ? 154 VAL B O   1 
ATOM   6864  C CB  . VAL B 1 134 ? 134.498 121.153 67.870  1.00 20.78  ? 154 VAL B CB  1 
ATOM   6865  C CG1 . VAL B 1 134 ? 134.434 120.802 66.398  1.00 20.74  ? 154 VAL B CG1 1 
ATOM   6866  C CG2 . VAL B 1 134 ? 135.924 121.482 68.281  1.00 21.08  ? 154 VAL B CG2 1 
ATOM   6867  N N   . ALA B 1 135 ? 131.344 121.219 68.360  1.00 20.49  ? 155 ALA B N   1 
ATOM   6868  C CA  . ALA B 1 135 ? 129.987 120.924 67.931  1.00 20.42  ? 155 ALA B CA  1 
ATOM   6869  C C   . ALA B 1 135 ? 129.146 122.195 67.937  1.00 20.84  ? 155 ALA B C   1 
ATOM   6870  O O   . ALA B 1 135 ? 128.304 122.375 67.062  1.00 21.30  ? 155 ALA B O   1 
ATOM   6871  C CB  . ALA B 1 135 ? 129.374 119.856 68.802  1.00 20.34  ? 155 ALA B CB  1 
ATOM   6872  N N   . ILE B 1 136 ? 129.375 123.073 68.919  1.00 21.29  ? 156 ILE B N   1 
ATOM   6873  C CA  . ILE B 1 136 ? 128.612 124.305 69.019  1.00 21.64  ? 156 ILE B CA  1 
ATOM   6874  C C   . ILE B 1 136 ? 128.913 125.210 67.827  1.00 22.26  ? 156 ILE B C   1 
ATOM   6875  O O   . ILE B 1 136 ? 127.992 125.775 67.241  1.00 22.44  ? 156 ILE B O   1 
ATOM   6876  C CB  . ILE B 1 136 ? 128.864 125.009 70.364  1.00 21.75  ? 156 ILE B CB  1 
ATOM   6877  C CG1 . ILE B 1 136 ? 128.114 124.283 71.483  1.00 22.07  ? 156 ILE B CG1 1 
ATOM   6878  C CG2 . ILE B 1 136 ? 128.500 126.486 70.277  1.00 21.92  ? 156 ILE B CG2 1 
ATOM   6879  C CD1 . ILE B 1 136 ? 127.977 125.061 72.764  1.00 22.54  ? 156 ILE B CD1 1 
ATOM   6880  N N   . GLN B 1 137 ? 130.196 125.356 67.480  1.00 23.05  ? 157 GLN B N   1 
ATOM   6881  C CA  . GLN B 1 137 ? 130.578 126.186 66.349  1.00 23.73  ? 157 GLN B CA  1 
ATOM   6882  C C   . GLN B 1 137 ? 129.965 125.634 65.067  1.00 23.54  ? 157 GLN B C   1 
ATOM   6883  O O   . GLN B 1 137 ? 129.363 126.379 64.293  1.00 24.19  ? 157 GLN B O   1 
ATOM   6884  C CB  . GLN B 1 137 ? 132.099 126.270 66.220  1.00 24.93  ? 157 GLN B CB  1 
ATOM   6885  C CG  . GLN B 1 137 ? 132.772 126.974 67.389  1.00 26.20  ? 157 GLN B CG  1 
ATOM   6886  C CD  . GLN B 1 137 ? 132.276 128.387 67.594  1.00 27.33  ? 157 GLN B CD  1 
ATOM   6887  O OE1 . GLN B 1 137 ? 132.304 129.216 66.684  1.00 27.87  ? 157 GLN B OE1 1 
ATOM   6888  N NE2 . GLN B 1 137 ? 131.824 128.682 68.804  1.00 27.70  ? 157 GLN B NE2 1 
ATOM   6889  N N   . VAL B 1 138 ? 130.109 124.321 64.862  1.00 23.06  ? 158 VAL B N   1 
ATOM   6890  C CA  . VAL B 1 138 ? 129.623 123.676 63.654  1.00 22.80  ? 158 VAL B CA  1 
ATOM   6891  C C   . VAL B 1 138 ? 128.103 123.809 63.578  1.00 22.81  ? 158 VAL B C   1 
ATOM   6892  O O   . VAL B 1 138 ? 127.559 124.006 62.495  1.00 23.01  ? 158 VAL B O   1 
ATOM   6893  C CB  . VAL B 1 138 ? 130.076 122.205 63.595  1.00 22.78  ? 158 VAL B CB  1 
ATOM   6894  C CG1 . VAL B 1 138 ? 129.385 121.431 62.484  1.00 22.81  ? 158 VAL B CG1 1 
ATOM   6895  C CG2 . VAL B 1 138 ? 131.585 122.100 63.456  1.00 22.97  ? 158 VAL B CG2 1 
ATOM   6896  N N   . GLN B 1 139 ? 127.425 123.706 64.727  1.00 22.88  ? 159 GLN B N   1 
ATOM   6897  C CA  . GLN B 1 139 ? 125.975 123.783 64.765  1.00 23.10  ? 159 GLN B CA  1 
ATOM   6898  C C   . GLN B 1 139 ? 125.519 125.196 64.417  1.00 23.92  ? 159 GLN B C   1 
ATOM   6899  O O   . GLN B 1 139 ? 124.546 125.372 63.687  1.00 24.76  ? 159 GLN B O   1 
ATOM   6900  C CB  . GLN B 1 139 ? 125.447 123.371 66.139  1.00 22.95  ? 159 GLN B CB  1 
ATOM   6901  C CG  . GLN B 1 139 ? 123.938 123.514 66.287  1.00 23.00  ? 159 GLN B CG  1 
ATOM   6902  C CD  . GLN B 1 139 ? 123.189 122.756 65.217  1.00 23.24  ? 159 GLN B CD  1 
ATOM   6903  O OE1 . GLN B 1 139 ? 122.391 123.316 64.475  1.00 23.30  ? 159 GLN B OE1 1 
ATOM   6904  N NE2 . GLN B 1 139 ? 123.467 121.469 65.098  1.00 23.63  ? 159 GLN B NE2 1 
ATOM   6905  N N   . ASN B 1 140 ? 126.217 126.200 64.958  1.00 24.54  ? 160 ASN B N   1 
ATOM   6906  C CA  . ASN B 1 140 ? 125.900 127.582 64.645  1.00 25.09  ? 160 ASN B CA  1 
ATOM   6907  C C   . ASN B 1 140 ? 125.952 127.790 63.135  1.00 25.52  ? 160 ASN B C   1 
ATOM   6908  O O   . ASN B 1 140 ? 125.123 128.509 62.586  1.00 25.85  ? 160 ASN B O   1 
ATOM   6909  C CB  . ASN B 1 140 ? 126.815 128.570 65.369  1.00 25.58  ? 160 ASN B CB  1 
ATOM   6910  C CG  . ASN B 1 140 ? 126.565 128.610 66.862  1.00 26.20  ? 160 ASN B CG  1 
ATOM   6911  O OD1 . ASN B 1 140 ? 125.416 128.625 67.302  1.00 26.53  ? 160 ASN B OD1 1 
ATOM   6912  N ND2 . ASN B 1 140 ? 127.629 128.608 67.649  1.00 26.41  ? 160 ASN B ND2 1 
ATOM   6913  N N   . LEU B 1 141 ? 126.913 127.156 62.456  1.00 26.06  ? 161 LEU B N   1 
ATOM   6914  C CA  . LEU B 1 141 ? 127.004 127.330 61.017  1.00 26.53  ? 161 LEU B CA  1 
ATOM   6915  C C   . LEU B 1 141 ? 125.933 126.505 60.312  1.00 26.58  ? 161 LEU B C   1 
ATOM   6916  O O   . LEU B 1 141 ? 125.372 126.977 59.331  1.00 27.07  ? 161 LEU B O   1 
ATOM   6917  C CB  . LEU B 1 141 ? 128.387 126.945 60.493  1.00 27.16  ? 161 LEU B CB  1 
ATOM   6918  C CG  . LEU B 1 141 ? 128.571 127.200 58.997  1.00 27.73  ? 161 LEU B CG  1 
ATOM   6919  C CD1 . LEU B 1 141 ? 128.896 128.659 58.738  1.00 28.31  ? 161 LEU B CD1 1 
ATOM   6920  C CD2 . LEU B 1 141 ? 129.645 126.307 58.406  1.00 28.02  ? 161 LEU B CD2 1 
ATOM   6921  N N   . LEU B 1 142 ? 125.668 125.280 60.787  1.00 26.74  ? 162 LEU B N   1 
ATOM   6922  C CA  . LEU B 1 142 ? 124.838 124.343 60.041  1.00 26.98  ? 162 LEU B CA  1 
ATOM   6923  C C   . LEU B 1 142 ? 123.361 124.719 60.121  1.00 27.51  ? 162 LEU B C   1 
ATOM   6924  O O   . LEU B 1 142 ? 122.646 124.573 59.135  1.00 27.91  ? 162 LEU B O   1 
ATOM   6925  C CB  . LEU B 1 142 ? 125.052 122.918 60.561  1.00 26.87  ? 162 LEU B CB  1 
ATOM   6926  C CG  . LEU B 1 142 ? 126.368 122.241 60.175  1.00 26.68  ? 162 LEU B CG  1 
ATOM   6927  C CD1 . LEU B 1 142 ? 126.288 120.754 60.461  1.00 26.49  ? 162 LEU B CD1 1 
ATOM   6928  C CD2 . LEU B 1 142 ? 126.729 122.480 58.714  1.00 26.64  ? 162 LEU B CD2 1 
ATOM   6929  N N   . GLN B 1 143 ? 122.902 125.199 61.282  1.00 28.11  ? 163 GLN B N   1 
ATOM   6930  C CA  . GLN B 1 143 ? 121.481 125.447 61.481  1.00 28.58  ? 163 GLN B CA  1 
ATOM   6931  C C   . GLN B 1 143 ? 120.966 126.504 60.506  1.00 29.55  ? 163 GLN B C   1 
ATOM   6932  O O   . GLN B 1 143 ? 119.764 126.575 60.270  1.00 30.10  ? 163 GLN B O   1 
ATOM   6933  C CB  . GLN B 1 143 ? 121.180 125.869 62.919  1.00 28.67  ? 163 GLN B CB  1 
ATOM   6934  C CG  . GLN B 1 143 ? 121.738 127.230 63.299  1.00 29.18  ? 163 GLN B CG  1 
ATOM   6935  C CD  . GLN B 1 143 ? 121.473 127.553 64.750  1.00 29.88  ? 163 GLN B CD  1 
ATOM   6936  O OE1 . GLN B 1 143 ? 120.809 126.804 65.466  1.00 29.92  ? 163 GLN B OE1 1 
ATOM   6937  N NE2 . GLN B 1 143 ? 121.989 128.687 65.196  1.00 30.24  ? 163 GLN B NE2 1 
ATOM   6938  N N   . LEU B 1 144 ? 121.861 127.328 59.948  1.00 30.38  ? 164 LEU B N   1 
ATOM   6939  C CA  . LEU B 1 144 ? 121.460 128.333 58.974  1.00 31.25  ? 164 LEU B CA  1 
ATOM   6940  C C   . LEU B 1 144 ? 121.018 127.670 57.671  1.00 32.26  ? 164 LEU B C   1 
ATOM   6941  O O   . LEU B 1 144 ? 120.236 128.256 56.928  1.00 32.99  ? 164 LEU B O   1 
ATOM   6942  C CB  . LEU B 1 144 ? 122.621 129.297 58.708  1.00 31.47  ? 164 LEU B CB  1 
ATOM   6943  C CG  . LEU B 1 144 ? 123.191 130.026 59.923  1.00 31.91  ? 164 LEU B CG  1 
ATOM   6944  C CD1 . LEU B 1 144 ? 124.211 131.065 59.486  1.00 32.13  ? 164 LEU B CD1 1 
ATOM   6945  C CD2 . LEU B 1 144 ? 122.093 130.677 60.752  1.00 32.09  ? 164 LEU B CD2 1 
ATOM   6946  N N   . PHE B 1 145 ? 121.524 126.460 57.394  1.00 33.06  ? 165 PHE B N   1 
ATOM   6947  C CA  . PHE B 1 145 ? 121.255 125.784 56.134  1.00 33.89  ? 165 PHE B CA  1 
ATOM   6948  C C   . PHE B 1 145 ? 120.338 124.576 56.325  1.00 32.98  ? 165 PHE B C   1 
ATOM   6949  O O   . PHE B 1 145 ? 120.115 123.824 55.378  1.00 32.68  ? 165 PHE B O   1 
ATOM   6950  C CB  . PHE B 1 145 ? 122.571 125.372 55.471  1.00 35.21  ? 165 PHE B CB  1 
ATOM   6951  C CG  . PHE B 1 145 ? 123.398 126.535 54.987  1.00 37.10  ? 165 PHE B CG  1 
ATOM   6952  C CD1 . PHE B 1 145 ? 124.087 127.338 55.880  1.00 37.85  ? 165 PHE B CD1 1 
ATOM   6953  C CD2 . PHE B 1 145 ? 123.452 126.852 53.639  1.00 39.11  ? 165 PHE B CD2 1 
ATOM   6954  C CE1 . PHE B 1 145 ? 124.842 128.412 55.431  1.00 38.99  ? 165 PHE B CE1 1 
ATOM   6955  C CE2 . PHE B 1 145 ? 124.197 127.930 53.191  1.00 39.98  ? 165 PHE B CE2 1 
ATOM   6956  C CZ  . PHE B 1 145 ? 124.893 128.709 54.087  1.00 39.92  ? 165 PHE B CZ  1 
ATOM   6957  N N   . ASN B 1 146 ? 119.801 124.406 57.540  1.00 32.66  ? 166 ASN B N   1 
ATOM   6958  C CA  . ASN B 1 146 ? 118.893 123.314 57.853  1.00 32.77  ? 166 ASN B CA  1 
ATOM   6959  C C   . ASN B 1 146 ? 119.575 121.978 57.564  1.00 31.92  ? 166 ASN B C   1 
ATOM   6960  O O   . ASN B 1 146 ? 119.109 121.199 56.736  1.00 32.77  ? 166 ASN B O   1 
ATOM   6961  C CB  . ASN B 1 146 ? 117.566 123.444 57.103  1.00 33.88  ? 166 ASN B CB  1 
ATOM   6962  C CG  . ASN B 1 146 ? 116.870 124.764 57.356  1.00 34.66  ? 166 ASN B CG  1 
ATOM   6963  O OD1 . ASN B 1 146 ? 116.632 125.135 58.503  1.00 34.91  ? 166 ASN B OD1 1 
ATOM   6964  N ND2 . ASN B 1 146 ? 116.545 125.483 56.292  1.00 35.15  ? 166 ASN B ND2 1 
ATOM   6965  N N   . ILE B 1 147 ? 120.691 121.732 58.254  1.00 30.38  ? 167 ILE B N   1 
ATOM   6966  C CA  . ILE B 1 147 ? 121.413 120.477 58.143  1.00 28.88  ? 167 ILE B CA  1 
ATOM   6967  C C   . ILE B 1 147 ? 121.439 119.837 59.524  1.00 27.90  ? 167 ILE B C   1 
ATOM   6968  O O   . ILE B 1 147 ? 122.173 120.289 60.399  1.00 27.85  ? 167 ILE B O   1 
ATOM   6969  C CB  . ILE B 1 147 ? 122.830 120.698 57.579  1.00 28.82  ? 167 ILE B CB  1 
ATOM   6970  C CG1 . ILE B 1 147 ? 122.781 121.365 56.202  1.00 28.99  ? 167 ILE B CG1 1 
ATOM   6971  C CG2 . ILE B 1 147 ? 123.605 119.388 57.547  1.00 29.27  ? 167 ILE B CG2 1 
ATOM   6972  C CD1 . ILE B 1 147 ? 124.134 121.626 55.589  1.00 29.26  ? 167 ILE B CD1 1 
ATOM   6973  N N   . PRO B 1 148 ? 120.626 118.786 59.768  1.00 27.45  ? 168 PRO B N   1 
ATOM   6974  C CA  . PRO B 1 148 ? 120.640 118.088 61.052  1.00 26.97  ? 168 PRO B CA  1 
ATOM   6975  C C   . PRO B 1 148 ? 122.034 117.567 61.387  1.00 26.19  ? 168 PRO B C   1 
ATOM   6976  O O   . PRO B 1 148 ? 122.768 117.110 60.508  1.00 26.52  ? 168 PRO B O   1 
ATOM   6977  C CB  . PRO B 1 148 ? 119.648 116.932 60.863  1.00 27.32  ? 168 PRO B CB  1 
ATOM   6978  C CG  . PRO B 1 148 ? 118.741 117.412 59.750  1.00 27.80  ? 168 PRO B CG  1 
ATOM   6979  C CD  . PRO B 1 148 ? 119.634 118.227 58.839  1.00 27.71  ? 168 PRO B CD  1 
ATOM   6980  N N   . GLN B 1 149 ? 122.382 117.654 62.673  1.00 25.13  ? 169 GLN B N   1 
ATOM   6981  C CA  . GLN B 1 149 ? 123.695 117.261 63.148  1.00 24.22  ? 169 GLN B CA  1 
ATOM   6982  C C   . GLN B 1 149 ? 123.518 116.309 64.321  1.00 23.79  ? 169 GLN B C   1 
ATOM   6983  O O   . GLN B 1 149 ? 123.028 116.717 65.370  1.00 24.48  ? 169 GLN B O   1 
ATOM   6984  C CB  . GLN B 1 149 ? 124.485 118.496 63.575  1.00 23.86  ? 169 GLN B CB  1 
ATOM   6985  C CG  . GLN B 1 149 ? 125.826 118.178 64.214  1.00 23.66  ? 169 GLN B CG  1 
ATOM   6986  C CD  . GLN B 1 149 ? 126.488 119.414 64.763  1.00 23.55  ? 169 GLN B CD  1 
ATOM   6987  O OE1 . GLN B 1 149 ? 126.368 120.499 64.203  1.00 23.67  ? 169 GLN B OE1 1 
ATOM   6988  N NE2 . GLN B 1 149 ? 127.186 119.259 65.876  1.00 23.69  ? 169 GLN B NE2 1 
ATOM   6989  N N   . ILE B 1 150 ? 123.913 115.048 64.130  1.00 23.04  ? 170 ILE B N   1 
ATOM   6990  C CA  . ILE B 1 150 ? 123.787 114.049 65.177  1.00 22.71  ? 170 ILE B CA  1 
ATOM   6991  C C   . ILE B 1 150 ? 125.178 113.765 65.730  1.00 22.45  ? 170 ILE B C   1 
ATOM   6992  O O   . ILE B 1 150 ? 126.024 113.222 65.025  1.00 22.93  ? 170 ILE B O   1 
ATOM   6993  C CB  . ILE B 1 150 ? 123.102 112.773 64.652  1.00 22.78  ? 170 ILE B CB  1 
ATOM   6994  C CG1 . ILE B 1 150 ? 121.795 113.102 63.921  1.00 23.13  ? 170 ILE B CG1 1 
ATOM   6995  C CG2 . ILE B 1 150 ? 122.902 111.785 65.794  1.00 22.80  ? 170 ILE B CG2 1 
ATOM   6996  C CD1 . ILE B 1 150 ? 121.075 111.914 63.341  1.00 23.57  ? 170 ILE B CD1 1 
ATOM   6997  N N   . ALA B 1 151 ? 125.403 114.145 66.992  1.00 22.19  ? 171 ALA B N   1 
ATOM   6998  C CA  . ALA B 1 151 ? 126.675 113.915 67.656  1.00 22.35  ? 171 ALA B CA  1 
ATOM   6999  C C   . ALA B 1 151 ? 126.698 112.517 68.267  1.00 22.74  ? 171 ALA B C   1 
ATOM   7000  O O   . ALA B 1 151 ? 125.676 111.835 68.324  1.00 23.16  ? 171 ALA B O   1 
ATOM   7001  C CB  . ALA B 1 151 ? 126.907 114.969 68.708  1.00 22.28  ? 171 ALA B CB  1 
ATOM   7002  N N   . TYR B 1 152 ? 127.884 112.104 68.718  1.00 23.18  ? 172 TYR B N   1 
ATOM   7003  C CA  . TYR B 1 152 ? 128.063 110.811 69.354  1.00 23.55  ? 172 TYR B CA  1 
ATOM   7004  C C   . TYR B 1 152 ? 128.790 110.953 70.690  1.00 24.02  ? 172 TYR B C   1 
ATOM   7005  O O   . TYR B 1 152 ? 128.757 110.021 71.484  1.00 24.22  ? 172 TYR B O   1 
ATOM   7006  C CB  . TYR B 1 152 ? 128.806 109.854 68.416  1.00 23.75  ? 172 TYR B CB  1 
ATOM   7007  C CG  . TYR B 1 152 ? 130.003 110.469 67.738  1.00 24.01  ? 172 TYR B CG  1 
ATOM   7008  C CD1 . TYR B 1 152 ? 131.165 110.754 68.434  1.00 24.18  ? 172 TYR B CD1 1 
ATOM   7009  C CD2 . TYR B 1 152 ? 129.955 110.808 66.400  1.00 24.36  ? 172 TYR B CD2 1 
ATOM   7010  C CE1 . TYR B 1 152 ? 132.257 111.335 67.812  1.00 24.68  ? 172 TYR B CE1 1 
ATOM   7011  C CE2 . TYR B 1 152 ? 131.037 111.393 65.761  1.00 24.65  ? 172 TYR B CE2 1 
ATOM   7012  C CZ  . TYR B 1 152 ? 132.193 111.660 66.469  1.00 24.86  ? 172 TYR B CZ  1 
ATOM   7013  O OH  . TYR B 1 152 ? 133.260 112.235 65.817  1.00 25.17  ? 172 TYR B OH  1 
ATOM   7014  N N   . SER B 1 153 ? 129.467 112.086 70.936  1.00 24.48  ? 173 SER B N   1 
ATOM   7015  C CA  . SER B 1 153 ? 130.167 112.271 72.200  1.00 24.93  ? 173 SER B CA  1 
ATOM   7016  C C   . SER B 1 153 ? 130.003 113.680 72.768  1.00 24.67  ? 173 SER B C   1 
ATOM   7017  O O   . SER B 1 153 ? 130.468 113.929 73.874  1.00 24.79  ? 173 SER B O   1 
ATOM   7018  C CB  . SER B 1 153 ? 131.631 111.912 72.073  1.00 25.61  ? 173 SER B CB  1 
ATOM   7019  O OG  . SER B 1 153 ? 132.338 112.877 71.311  1.00 25.93  ? 173 SER B OG  1 
ATOM   7020  N N   . ALA B 1 154 ? 129.360 114.602 72.043  1.00 24.84  ? 174 ALA B N   1 
ATOM   7021  C CA  . ALA B 1 154 ? 129.090 115.920 72.600  1.00 25.26  ? 174 ALA B CA  1 
ATOM   7022  C C   . ALA B 1 154 ? 128.124 115.766 73.771  1.00 26.12  ? 174 ALA B C   1 
ATOM   7023  O O   . ALA B 1 154 ? 127.035 115.227 73.598  1.00 26.54  ? 174 ALA B O   1 
ATOM   7024  C CB  . ALA B 1 154 ? 128.534 116.825 71.533  1.00 25.20  ? 174 ALA B CB  1 
ATOM   7025  N N   . THR B 1 155 ? 128.529 116.227 74.962  1.00 27.16  ? 175 THR B N   1 
ATOM   7026  C CA  . THR B 1 155 ? 127.824 115.868 76.184  1.00 28.21  ? 175 THR B CA  1 
ATOM   7027  C C   . THR B 1 155 ? 127.415 117.092 77.003  1.00 29.22  ? 175 THR B C   1 
ATOM   7028  O O   . THR B 1 155 ? 126.661 116.951 77.960  1.00 30.03  ? 175 THR B O   1 
ATOM   7029  C CB  . THR B 1 155 ? 128.671 114.924 77.047  1.00 28.85  ? 175 THR B CB  1 
ATOM   7030  O OG1 . THR B 1 155 ? 129.360 114.019 76.187  1.00 29.40  ? 175 THR B OG1 1 
ATOM   7031  C CG2 . THR B 1 155 ? 127.852 114.129 78.041  1.00 29.65  ? 175 THR B CG2 1 
ATOM   7032  N N   . SER B 1 156 ? 127.899 118.289 76.648  1.00 30.20  ? 176 SER B N   1 
ATOM   7033  C CA  . SER B 1 156 ? 127.608 119.470 77.444  1.00 31.27  ? 176 SER B CA  1 
ATOM   7034  C C   . SER B 1 156 ? 126.108 119.743 77.438  1.00 32.71  ? 176 SER B C   1 
ATOM   7035  O O   . SER B 1 156 ? 125.419 119.452 76.464  1.00 32.63  ? 176 SER B O   1 
ATOM   7036  C CB  . SER B 1 156 ? 128.372 120.670 76.959  1.00 31.17  ? 176 SER B CB  1 
ATOM   7037  O OG  . SER B 1 156 ? 127.989 121.012 75.639  1.00 30.96  ? 176 SER B OG  1 
ATOM   7038  N N   . MET B 1 157 ? 125.630 120.342 78.530  1.00 35.15  ? 177 MET B N   1 
ATOM   7039  C CA  . MET B 1 157 ? 124.219 120.629 78.718  1.00 37.87  ? 177 MET B CA  1 
ATOM   7040  C C   . MET B 1 157 ? 123.793 121.781 77.809  1.00 38.23  ? 177 MET B C   1 
ATOM   7041  O O   . MET B 1 157 ? 122.610 121.934 77.508  1.00 38.55  ? 177 MET B O   1 
ATOM   7042  C CB  . MET B 1 157 ? 123.955 121.031 80.171  1.00 40.67  ? 177 MET B CB  1 
ATOM   7043  C CG  . MET B 1 157 ? 124.594 120.100 81.185  1.00 43.12  ? 177 MET B CG  1 
ATOM   7044  S SD  . MET B 1 157 ? 124.403 120.701 82.876  1.00 47.33  ? 177 MET B SD  1 
ATOM   7045  C CE  . MET B 1 157 ? 122.614 120.756 82.978  1.00 47.92  ? 177 MET B CE  1 
ATOM   7046  N N   . ASP B 1 158 ? 124.763 122.605 77.393  1.00 38.21  ? 178 ASP B N   1 
ATOM   7047  C CA  . ASP B 1 158 ? 124.483 123.786 76.594  1.00 38.51  ? 178 ASP B CA  1 
ATOM   7048  C C   . ASP B 1 158 ? 123.821 123.395 75.277  1.00 37.29  ? 178 ASP B C   1 
ATOM   7049  O O   . ASP B 1 158 ? 122.990 124.139 74.764  1.00 38.25  ? 178 ASP B O   1 
ATOM   7050  C CB  . ASP B 1 158 ? 125.759 124.597 76.378  1.00 39.76  ? 178 ASP B CB  1 
ATOM   7051  C CG  . ASP B 1 158 ? 126.295 125.178 77.675  1.00 41.84  ? 178 ASP B CG  1 
ATOM   7052  O OD1 . ASP B 1 158 ? 125.742 124.839 78.744  1.00 42.53  ? 178 ASP B OD1 1 
ATOM   7053  O OD2 . ASP B 1 158 ? 127.253 125.972 77.606  1.00 43.03  ? 178 ASP B OD2 1 
ATOM   7054  N N   . LEU B 1 159 ? 124.173 122.217 74.752  1.00 35.74  ? 179 LEU B N   1 
ATOM   7055  C CA  . LEU B 1 159 ? 123.641 121.751 73.482  1.00 35.08  ? 179 LEU B CA  1 
ATOM   7056  C C   . LEU B 1 159 ? 122.204 121.249 73.620  1.00 36.27  ? 179 LEU B C   1 
ATOM   7057  O O   . LEU B 1 159 ? 121.554 120.996 72.608  1.00 36.61  ? 179 LEU B O   1 
ATOM   7058  C CB  . LEU B 1 159 ? 124.558 120.652 72.943  1.00 34.06  ? 179 LEU B CB  1 
ATOM   7059  C CG  . LEU B 1 159 ? 125.857 121.145 72.310  1.00 33.28  ? 179 LEU B CG  1 
ATOM   7060  C CD1 . LEU B 1 159 ? 126.879 120.027 72.235  1.00 33.24  ? 179 LEU B CD1 1 
ATOM   7061  C CD2 . LEU B 1 159 ? 125.601 121.713 70.925  1.00 33.12  ? 179 LEU B CD2 1 
ATOM   7062  N N   . SER B 1 160 ? 121.708 121.110 74.857  1.00 37.65  ? 180 SER B N   1 
ATOM   7063  C CA  . SER B 1 160 ? 120.360 120.614 75.099  1.00 39.07  ? 180 SER B CA  1 
ATOM   7064  C C   . SER B 1 160 ? 119.312 121.684 74.793  1.00 40.59  ? 180 SER B C   1 
ATOM   7065  O O   . SER B 1 160 ? 118.153 121.353 74.543  1.00 40.69  ? 180 SER B O   1 
ATOM   7066  C CB  . SER B 1 160 ? 120.224 120.121 76.514  1.00 39.57  ? 180 SER B CB  1 
ATOM   7067  O OG  . SER B 1 160 ? 119.190 119.162 76.615  1.00 40.06  ? 180 SER B OG  1 
ATOM   7068  N N   . ASP B 1 161 ? 119.723 122.959 74.840  1.00 42.20  ? 181 ASP B N   1 
ATOM   7069  C CA  . ASP B 1 161 ? 118.824 124.075 74.594  1.00 43.17  ? 181 ASP B CA  1 
ATOM   7070  C C   . ASP B 1 161 ? 118.449 124.118 73.114  1.00 41.66  ? 181 ASP B C   1 
ATOM   7071  O O   . ASP B 1 161 ? 119.278 124.434 72.262  1.00 41.20  ? 181 ASP B O   1 
ATOM   7072  C CB  . ASP B 1 161 ? 119.457 125.393 75.040  1.00 45.16  ? 181 ASP B CB  1 
ATOM   7073  C CG  . ASP B 1 161 ? 118.510 126.581 74.990  1.00 47.75  ? 181 ASP B CG  1 
ATOM   7074  O OD1 . ASP B 1 161 ? 117.502 126.529 74.242  1.00 47.85  ? 181 ASP B OD1 1 
ATOM   7075  O OD2 . ASP B 1 161 ? 118.771 127.544 75.737  1.00 49.38  ? 181 ASP B OD2 1 
ATOM   7076  N N   . LYS B 1 162 ? 117.182 123.806 72.820  1.00 40.77  ? 182 LYS B N   1 
ATOM   7077  C CA  . LYS B 1 162 ? 116.716 123.653 71.452  1.00 40.47  ? 182 LYS B CA  1 
ATOM   7078  C C   . LYS B 1 162 ? 116.348 124.992 70.817  1.00 40.15  ? 182 LYS B C   1 
ATOM   7079  O O   . LYS B 1 162 ? 116.059 125.026 69.624  1.00 39.83  ? 182 LYS B O   1 
ATOM   7080  C CB  . LYS B 1 162 ? 115.503 122.721 71.420  1.00 41.06  ? 182 LYS B CB  1 
ATOM   7081  C CG  . LYS B 1 162 ? 115.867 121.253 71.319  1.00 41.41  ? 182 LYS B CG  1 
ATOM   7082  C CD  . LYS B 1 162 ? 116.494 120.915 69.992  1.00 41.25  ? 182 LYS B CD  1 
ATOM   7083  C CE  . LYS B 1 162 ? 117.499 119.784 70.055  1.00 40.68  ? 182 LYS B CE  1 
ATOM   7084  N NZ  . LYS B 1 162 ? 118.748 120.157 70.759  1.00 40.12  ? 182 LYS B NZ  1 
ATOM   7085  N N   . THR B 1 163 ? 116.359 126.084 71.593  1.00 39.99  ? 183 THR B N   1 
ATOM   7086  C CA  . THR B 1 163 ? 116.098 127.395 71.021  1.00 39.76  ? 183 THR B CA  1 
ATOM   7087  C C   . THR B 1 163 ? 117.340 127.865 70.265  1.00 39.00  ? 183 THR B C   1 
ATOM   7088  O O   . THR B 1 163 ? 117.228 128.450 69.192  1.00 39.60  ? 183 THR B O   1 
ATOM   7089  C CB  . THR B 1 163 ? 115.663 128.413 72.082  1.00 40.58  ? 183 THR B CB  1 
ATOM   7090  O OG1 . THR B 1 163 ? 116.813 128.838 72.811  1.00 40.80  ? 183 THR B OG1 1 
ATOM   7091  C CG2 . THR B 1 163 ? 114.609 127.876 73.026  1.00 41.16  ? 183 THR B CG2 1 
ATOM   7092  N N   . LEU B 1 164 ? 118.520 127.593 70.835  1.00 37.55  ? 184 LEU B N   1 
ATOM   7093  C CA  . LEU B 1 164 ? 119.789 128.004 70.252  1.00 36.27  ? 184 LEU B CA  1 
ATOM   7094  C C   . LEU B 1 164 ? 120.299 126.942 69.280  1.00 34.62  ? 184 LEU B C   1 
ATOM   7095  O O   . LEU B 1 164 ? 120.884 127.280 68.255  1.00 34.49  ? 184 LEU B O   1 
ATOM   7096  C CB  . LEU B 1 164 ? 120.796 128.221 71.383  1.00 36.86  ? 184 LEU B CB  1 
ATOM   7097  C CG  . LEU B 1 164 ? 120.422 129.302 72.394  1.00 38.09  ? 184 LEU B CG  1 
ATOM   7098  C CD1 . LEU B 1 164 ? 121.238 129.162 73.671  1.00 38.46  ? 184 LEU B CD1 1 
ATOM   7099  C CD2 . LEU B 1 164 ? 120.618 130.686 71.793  1.00 39.06  ? 184 LEU B CD2 1 
ATOM   7100  N N   . PHE B 1 165 ? 120.106 125.663 69.627  1.00 33.15  ? 185 PHE B N   1 
ATOM   7101  C CA  . PHE B 1 165 ? 120.600 124.561 68.817  1.00 31.92  ? 185 PHE B CA  1 
ATOM   7102  C C   . PHE B 1 165 ? 119.429 123.669 68.422  1.00 32.18  ? 185 PHE B C   1 
ATOM   7103  O O   . PHE B 1 165 ? 119.148 122.681 69.095  1.00 32.90  ? 185 PHE B O   1 
ATOM   7104  C CB  . PHE B 1 165 ? 121.662 123.774 69.592  1.00 30.93  ? 185 PHE B CB  1 
ATOM   7105  C CG  . PHE B 1 165 ? 122.768 124.617 70.173  1.00 29.86  ? 185 PHE B CG  1 
ATOM   7106  C CD1 . PHE B 1 165 ? 123.689 125.243 69.349  1.00 29.57  ? 185 PHE B CD1 1 
ATOM   7107  C CD2 . PHE B 1 165 ? 122.880 124.797 71.543  1.00 29.29  ? 185 PHE B CD2 1 
ATOM   7108  C CE1 . PHE B 1 165 ? 124.703 126.024 69.882  1.00 29.20  ? 185 PHE B CE1 1 
ATOM   7109  C CE2 . PHE B 1 165 ? 123.896 125.578 72.073  1.00 28.92  ? 185 PHE B CE2 1 
ATOM   7110  C CZ  . PHE B 1 165 ? 124.805 126.189 71.243  1.00 28.90  ? 185 PHE B CZ  1 
ATOM   7111  N N   . LYS B 1 166 ? 118.748 124.022 67.327  1.00 32.41  ? 186 LYS B N   1 
ATOM   7112  C CA  . LYS B 1 166 ? 117.548 123.302 66.934  1.00 32.96  ? 186 LYS B CA  1 
ATOM   7113  C C   . LYS B 1 166 ? 117.915 122.042 66.157  1.00 32.31  ? 186 LYS B C   1 
ATOM   7114  O O   . LYS B 1 166 ? 117.365 120.974 66.412  1.00 32.84  ? 186 LYS B O   1 
ATOM   7115  C CB  . LYS B 1 166 ? 116.605 124.164 66.092  1.00 34.52  ? 186 LYS B CB  1 
ATOM   7116  C CG  . LYS B 1 166 ? 115.227 123.542 65.908  1.00 36.04  ? 186 LYS B CG  1 
ATOM   7117  C CD  . LYS B 1 166 ? 114.145 124.514 65.492  1.00 37.17  ? 186 LYS B CD  1 
ATOM   7118  C CE  . LYS B 1 166 ? 114.181 124.843 64.016  1.00 38.20  ? 186 LYS B CE  1 
ATOM   7119  N NZ  . LYS B 1 166 ? 113.669 123.717 63.200  1.00 38.50  ? 186 LYS B NZ  1 
ATOM   7120  N N   . TYR B 1 167 ? 118.846 122.173 65.211  1.00 31.64  ? 187 TYR B N   1 
ATOM   7121  C CA  . TYR B 1 167 ? 119.254 121.056 64.374  1.00 31.48  ? 187 TYR B CA  1 
ATOM   7122  C C   . TYR B 1 167 ? 120.429 120.318 65.010  1.00 30.16  ? 187 TYR B C   1 
ATOM   7123  O O   . TYR B 1 167 ? 121.464 120.117 64.374  1.00 30.45  ? 187 TYR B O   1 
ATOM   7124  C CB  . TYR B 1 167 ? 119.636 121.541 62.977  1.00 32.83  ? 187 TYR B CB  1 
ATOM   7125  C CG  . TYR B 1 167 ? 118.479 122.046 62.161  1.00 34.89  ? 187 TYR B CG  1 
ATOM   7126  C CD1 . TYR B 1 167 ? 117.847 123.241 62.469  1.00 36.16  ? 187 TYR B CD1 1 
ATOM   7127  C CD2 . TYR B 1 167 ? 118.012 121.320 61.079  1.00 36.26  ? 187 TYR B CD2 1 
ATOM   7128  C CE1 . TYR B 1 167 ? 116.791 123.715 61.706  1.00 36.91  ? 187 TYR B CE1 1 
ATOM   7129  C CE2 . TYR B 1 167 ? 116.944 121.770 60.320  1.00 37.22  ? 187 TYR B CE2 1 
ATOM   7130  C CZ  . TYR B 1 167 ? 116.337 122.975 60.630  1.00 37.45  ? 187 TYR B CZ  1 
ATOM   7131  O OH  . TYR B 1 167 ? 115.278 123.421 59.882  1.00 38.49  ? 187 TYR B OH  1 
ATOM   7132  N N   . PHE B 1 168 ? 120.267 119.926 66.272  1.00 28.76  ? 188 PHE B N   1 
ATOM   7133  C CA  . PHE B 1 168 ? 121.289 119.164 66.958  1.00 27.80  ? 188 PHE B CA  1 
ATOM   7134  C C   . PHE B 1 168 ? 120.630 118.041 67.744  1.00 28.42  ? 188 PHE B C   1 
ATOM   7135  O O   . PHE B 1 168 ? 119.713 118.281 68.524  1.00 29.39  ? 188 PHE B O   1 
ATOM   7136  C CB  . PHE B 1 168 ? 122.096 120.044 67.910  1.00 26.95  ? 188 PHE B CB  1 
ATOM   7137  C CG  . PHE B 1 168 ? 123.241 119.314 68.559  1.00 26.25  ? 188 PHE B CG  1 
ATOM   7138  C CD1 . PHE B 1 168 ? 124.393 119.025 67.846  1.00 25.70  ? 188 PHE B CD1 1 
ATOM   7139  C CD2 . PHE B 1 168 ? 123.145 118.869 69.867  1.00 26.15  ? 188 PHE B CD2 1 
ATOM   7140  C CE1 . PHE B 1 168 ? 125.439 118.342 68.443  1.00 25.64  ? 188 PHE B CE1 1 
ATOM   7141  C CE2 . PHE B 1 168 ? 124.191 118.183 70.459  1.00 25.89  ? 188 PHE B CE2 1 
ATOM   7142  C CZ  . PHE B 1 168 ? 125.334 117.918 69.746  1.00 25.70  ? 188 PHE B CZ  1 
ATOM   7143  N N   . MET B 1 169 ? 121.116 116.818 67.532  1.00 28.31  ? 189 MET B N   1 
ATOM   7144  C CA  . MET B 1 169 ? 120.696 115.682 68.329  1.00 28.62  ? 189 MET B CA  1 
ATOM   7145  C C   . MET B 1 169 ? 121.945 114.925 68.757  1.00 27.81  ? 189 MET B C   1 
ATOM   7146  O O   . MET B 1 169 ? 123.007 115.095 68.167  1.00 28.14  ? 189 MET B O   1 
ATOM   7147  C CB  . MET B 1 169 ? 119.802 114.743 67.523  1.00 29.97  ? 189 MET B CB  1 
ATOM   7148  C CG  . MET B 1 169 ? 118.546 115.398 67.017  1.00 31.34  ? 189 MET B CG  1 
ATOM   7149  S SD  . MET B 1 169 ? 117.899 114.446 65.635  1.00 34.32  ? 189 MET B SD  1 
ATOM   7150  C CE  . MET B 1 169 ? 118.338 115.533 64.279  1.00 35.33  ? 189 MET B CE  1 
ATOM   7151  N N   . ARG B 1 170 ? 121.808 114.089 69.781  1.00 26.85  ? 190 ARG B N   1 
ATOM   7152  C CA  . ARG B 1 170 ? 122.915 113.260 70.209  1.00 26.31  ? 190 ARG B CA  1 
ATOM   7153  C C   . ARG B 1 170 ? 122.365 111.941 70.723  1.00 26.05  ? 190 ARG B C   1 
ATOM   7154  O O   . ARG B 1 170 ? 121.254 111.884 71.240  1.00 26.88  ? 190 ARG B O   1 
ATOM   7155  C CB  . ARG B 1 170 ? 123.757 113.977 71.266  1.00 26.31  ? 190 ARG B CB  1 
ATOM   7156  C CG  . ARG B 1 170 ? 122.943 114.656 72.356  1.00 26.64  ? 190 ARG B CG  1 
ATOM   7157  C CD  . ARG B 1 170 ? 123.864 115.341 73.340  1.00 26.93  ? 190 ARG B CD  1 
ATOM   7158  N NE  . ARG B 1 170 ? 123.141 116.278 74.181  1.00 27.33  ? 190 ARG B NE  1 
ATOM   7159  C CZ  . ARG B 1 170 ? 123.704 117.257 74.877  1.00 27.84  ? 190 ARG B CZ  1 
ATOM   7160  N NH1 . ARG B 1 170 ? 125.004 117.477 74.795  1.00 27.96  ? 190 ARG B NH1 1 
ATOM   7161  N NH2 . ARG B 1 170 ? 122.959 118.031 75.647  1.00 28.39  ? 190 ARG B NH2 1 
ATOM   7162  N N   . VAL B 1 171 ? 123.181 110.897 70.575  1.00 25.54  ? 191 VAL B N   1 
ATOM   7163  C CA  . VAL B 1 171 ? 122.807 109.553 70.967  1.00 25.30  ? 191 VAL B CA  1 
ATOM   7164  C C   . VAL B 1 171 ? 123.431 109.255 72.327  1.00 25.56  ? 191 VAL B C   1 
ATOM   7165  O O   . VAL B 1 171 ? 123.564 108.097 72.711  1.00 25.77  ? 191 VAL B O   1 
ATOM   7166  C CB  . VAL B 1 171 ? 123.229 108.541 69.887  1.00 25.33  ? 191 VAL B CB  1 
ATOM   7167  C CG1 . VAL B 1 171 ? 122.427 108.716 68.607  1.00 25.72  ? 191 VAL B CG1 1 
ATOM   7168  C CG2 . VAL B 1 171 ? 124.712 108.625 69.586  1.00 25.40  ? 191 VAL B CG2 1 
ATOM   7169  N N   . VAL B 1 172 ? 123.790 110.317 73.057  1.00 26.02  ? 192 VAL B N   1 
ATOM   7170  C CA  . VAL B 1 172 ? 124.371 110.193 74.382  1.00 26.64  ? 192 VAL B CA  1 
ATOM   7171  C C   . VAL B 1 172 ? 123.628 111.133 75.323  1.00 27.51  ? 192 VAL B C   1 
ATOM   7172  O O   . VAL B 1 172 ? 123.133 112.174 74.897  1.00 28.04  ? 192 VAL B O   1 
ATOM   7173  C CB  . VAL B 1 172 ? 125.879 110.506 74.369  1.00 26.71  ? 192 VAL B CB  1 
ATOM   7174  C CG1 . VAL B 1 172 ? 126.684 109.345 73.813  1.00 26.90  ? 192 VAL B CG1 1 
ATOM   7175  C CG2 . VAL B 1 172 ? 126.189 111.787 73.610  1.00 26.73  ? 192 VAL B CG2 1 
ATOM   7176  N N   . PRO B 1 173 ? 123.537 110.811 76.631  1.00 28.67  ? 193 PRO B N   1 
ATOM   7177  C CA  . PRO B 1 173 ? 122.932 111.725 77.597  1.00 29.92  ? 193 PRO B CA  1 
ATOM   7178  C C   . PRO B 1 173 ? 123.789 112.968 77.815  1.00 30.95  ? 193 PRO B C   1 
ATOM   7179  O O   . PRO B 1 173 ? 124.959 112.995 77.446  1.00 31.40  ? 193 PRO B O   1 
ATOM   7180  C CB  . PRO B 1 173 ? 122.826 110.877 78.873  1.00 29.84  ? 193 PRO B CB  1 
ATOM   7181  C CG  . PRO B 1 173 ? 123.937 109.855 78.732  1.00 29.33  ? 193 PRO B CG  1 
ATOM   7182  C CD  . PRO B 1 173 ? 124.010 109.564 77.249  1.00 28.87  ? 193 PRO B CD  1 
ATOM   7183  N N   . SER B 1 174 ? 123.176 113.993 78.410  1.00 32.04  ? 194 SER B N   1 
ATOM   7184  C CA  . SER B 1 174 ? 123.839 115.249 78.714  1.00 33.28  ? 194 SER B CA  1 
ATOM   7185  C C   . SER B 1 174 ? 124.821 115.069 79.872  1.00 34.13  ? 194 SER B C   1 
ATOM   7186  O O   . SER B 1 174 ? 124.894 114.002 80.475  1.00 34.57  ? 194 SER B O   1 
ATOM   7187  C CB  . SER B 1 174 ? 122.797 116.308 79.016  1.00 34.23  ? 194 SER B CB  1 
ATOM   7188  O OG  . SER B 1 174 ? 123.366 117.459 79.624  1.00 34.84  ? 194 SER B OG  1 
ATOM   7189  N N   . ASP B 1 175 ? 125.525 116.156 80.200  1.00 35.85  ? 195 ASP B N   1 
ATOM   7190  C CA  . ASP B 1 175 ? 126.509 116.173 81.266  1.00 37.75  ? 195 ASP B CA  1 
ATOM   7191  C C   . ASP B 1 175 ? 125.872 116.343 82.640  1.00 39.18  ? 195 ASP B C   1 
ATOM   7192  O O   . ASP B 1 175 ? 126.585 116.282 83.639  1.00 40.21  ? 195 ASP B O   1 
ATOM   7193  C CB  . ASP B 1 175 ? 127.507 117.318 81.081  1.00 39.41  ? 195 ASP B CB  1 
ATOM   7194  C CG  . ASP B 1 175 ? 128.854 116.858 80.565  1.00 40.62  ? 195 ASP B CG  1 
ATOM   7195  O OD1 . ASP B 1 175 ? 129.052 115.633 80.478  1.00 40.76  ? 195 ASP B OD1 1 
ATOM   7196  O OD2 . ASP B 1 175 ? 129.696 117.727 80.264  1.00 41.10  ? 195 ASP B OD2 1 
ATOM   7197  N N   . ALA B 1 176 ? 124.564 116.622 82.685  1.00 40.45  ? 196 ALA B N   1 
ATOM   7198  C CA  . ALA B 1 176 ? 123.864 116.761 83.952  1.00 42.10  ? 196 ALA B CA  1 
ATOM   7199  C C   . ALA B 1 176 ? 123.953 115.453 84.734  1.00 42.76  ? 196 ALA B C   1 
ATOM   7200  O O   . ALA B 1 176 ? 124.253 115.452 85.928  1.00 43.38  ? 196 ALA B O   1 
ATOM   7201  C CB  . ALA B 1 176 ? 122.428 117.154 83.711  1.00 42.98  ? 196 ALA B CB  1 
ATOM   7202  N N   . GLN B 1 177 ? 123.705 114.343 84.031  1.00 42.72  ? 197 GLN B N   1 
ATOM   7203  C CA  . GLN B 1 177 ? 123.710 113.027 84.642  1.00 43.44  ? 197 GLN B CA  1 
ATOM   7204  C C   . GLN B 1 177 ? 125.127 112.677 85.086  1.00 42.57  ? 197 GLN B C   1 
ATOM   7205  O O   . GLN B 1 177 ? 125.319 112.071 86.134  1.00 44.21  ? 197 GLN B O   1 
ATOM   7206  C CB  . GLN B 1 177 ? 123.161 111.986 83.666  1.00 45.59  ? 197 GLN B CB  1 
ATOM   7207  C CG  . GLN B 1 177 ? 121.759 112.307 83.166  1.00 48.30  ? 197 GLN B CG  1 
ATOM   7208  C CD  . GLN B 1 177 ? 121.128 111.153 82.427  1.00 51.25  ? 197 GLN B CD  1 
ATOM   7209  O OE1 . GLN B 1 177 ? 121.589 110.016 82.499  1.00 51.58  ? 197 GLN B OE1 1 
ATOM   7210  N NE2 . GLN B 1 177 ? 120.044 111.437 81.722  1.00 52.49  ? 197 GLN B NE2 1 
ATOM   7211  N N   . GLN B 1 178 ? 126.123 113.080 84.298  1.00 41.40  ? 198 GLN B N   1 
ATOM   7212  C CA  . GLN B 1 178 ? 127.504 112.783 84.632  1.00 41.37  ? 198 GLN B CA  1 
ATOM   7213  C C   . GLN B 1 178 ? 127.948 113.566 85.865  1.00 40.37  ? 198 GLN B C   1 
ATOM   7214  O O   . GLN B 1 178 ? 128.672 113.036 86.708  1.00 41.04  ? 198 GLN B O   1 
ATOM   7215  C CB  . GLN B 1 178 ? 128.399 113.089 83.438  1.00 42.35  ? 198 GLN B CB  1 
ATOM   7216  C CG  . GLN B 1 178 ? 129.796 112.538 83.609  1.00 43.25  ? 198 GLN B CG  1 
ATOM   7217  C CD  . GLN B 1 178 ? 130.534 112.439 82.298  1.00 44.36  ? 198 GLN B CD  1 
ATOM   7218  O OE1 . GLN B 1 178 ? 131.753 112.369 82.279  1.00 44.97  ? 198 GLN B OE1 1 
ATOM   7219  N NE2 . GLN B 1 178 ? 129.813 112.453 81.187  1.00 44.79  ? 198 GLN B NE2 1 
ATOM   7220  N N   . ALA B 1 179 ? 127.516 114.827 85.971  1.00 39.58  ? 199 ALA B N   1 
ATOM   7221  C CA  . ALA B 1 179 ? 127.838 115.627 87.141  1.00 40.13  ? 199 ALA B CA  1 
ATOM   7222  C C   . ALA B 1 179 ? 127.188 115.015 88.381  1.00 41.07  ? 199 ALA B C   1 
ATOM   7223  O O   . ALA B 1 179 ? 127.796 114.979 89.447  1.00 41.61  ? 199 ALA B O   1 
ATOM   7224  C CB  . ALA B 1 179 ? 127.421 117.063 86.928  1.00 40.58  ? 199 ALA B CB  1 
ATOM   7225  N N   . ARG B 1 180 ? 125.953 114.529 88.226  1.00 42.25  ? 200 ARG B N   1 
ATOM   7226  C CA  . ARG B 1 180 ? 125.250 113.870 89.313  1.00 43.29  ? 200 ARG B CA  1 
ATOM   7227  C C   . ARG B 1 180 ? 125.994 112.598 89.719  1.00 42.35  ? 200 ARG B C   1 
ATOM   7228  O O   . ARG B 1 180 ? 126.087 112.292 90.903  1.00 43.97  ? 200 ARG B O   1 
ATOM   7229  C CB  . ARG B 1 180 ? 123.802 113.574 88.912  1.00 45.65  ? 200 ARG B CB  1 
ATOM   7230  C CG  . ARG B 1 180 ? 123.002 112.837 89.974  1.00 48.67  ? 200 ARG B CG  1 
ATOM   7231  C CD  . ARG B 1 180 ? 123.092 113.462 91.354  1.00 51.08  ? 200 ARG B CD  1 
ATOM   7232  N NE  . ARG B 1 180 ? 122.520 114.796 91.402  1.00 54.05  ? 200 ARG B NE  1 
ATOM   7233  C CZ  . ARG B 1 180 ? 122.616 115.625 92.438  1.00 57.30  ? 200 ARG B CZ  1 
ATOM   7234  N NH1 . ARG B 1 180 ? 123.390 115.326 93.469  1.00 57.28  ? 200 ARG B NH1 1 
ATOM   7235  N NH2 . ARG B 1 180 ? 121.958 116.774 92.422  1.00 58.41  ? 200 ARG B NH2 1 
ATOM   7236  N N   . ALA B 1 181 ? 126.522 111.857 88.738  1.00 40.87  ? 201 ALA B N   1 
ATOM   7237  C CA  . ALA B 1 181 ? 127.278 110.647 89.026  1.00 40.47  ? 201 ALA B CA  1 
ATOM   7238  C C   . ALA B 1 181 ? 128.524 110.982 89.843  1.00 41.09  ? 201 ALA B C   1 
ATOM   7239  O O   . ALA B 1 181 ? 128.834 110.285 90.806  1.00 41.76  ? 201 ALA B O   1 
ATOM   7240  C CB  . ALA B 1 181 ? 127.638 109.929 87.749  1.00 40.43  ? 201 ALA B CB  1 
ATOM   7241  N N   . MET B 1 182 ? 129.235 112.049 89.461  1.00 42.34  ? 202 MET B N   1 
ATOM   7242  C CA  . MET B 1 182 ? 130.456 112.415 90.160  1.00 43.74  ? 202 MET B CA  1 
ATOM   7243  C C   . MET B 1 182 ? 130.132 112.831 91.596  1.00 44.43  ? 202 MET B C   1 
ATOM   7244  O O   . MET B 1 182 ? 130.860 112.472 92.521  1.00 45.41  ? 202 MET B O   1 
ATOM   7245  C CB  . MET B 1 182 ? 131.199 113.548 89.449  1.00 45.02  ? 202 MET B CB  1 
ATOM   7246  C CG  . MET B 1 182 ? 132.002 113.068 88.255  1.00 45.98  ? 202 MET B CG  1 
ATOM   7247  S SD  . MET B 1 182 ? 133.253 114.220 87.608  1.00 48.53  ? 202 MET B SD  1 
ATOM   7248  C CE  . MET B 1 182 ? 133.215 115.563 88.798  1.00 48.90  ? 202 MET B CE  1 
ATOM   7249  N N   . VAL B 1 183 ? 129.032 113.573 91.779  1.00 44.15  ? 203 VAL B N   1 
ATOM   7250  C CA  . VAL B 1 183 ? 128.624 114.021 93.102  1.00 44.05  ? 203 VAL B CA  1 
ATOM   7251  C C   . VAL B 1 183 ? 128.255 112.817 93.967  1.00 43.09  ? 203 VAL B C   1 
ATOM   7252  O O   . VAL B 1 183 ? 128.569 112.798 95.153  1.00 43.77  ? 203 VAL B O   1 
ATOM   7253  C CB  . VAL B 1 183 ? 127.466 115.036 93.033  1.00 45.64  ? 203 VAL B CB  1 
ATOM   7254  C CG1 . VAL B 1 183 ? 126.695 115.154 94.341  1.00 46.66  ? 203 VAL B CG1 1 
ATOM   7255  C CG2 . VAL B 1 183 ? 127.967 116.397 92.594  1.00 46.22  ? 203 VAL B CG2 1 
ATOM   7256  N N   . ASP B 1 184 ? 127.580 111.825 93.377  1.00 42.63  ? 204 ASP B N   1 
ATOM   7257  C CA  . ASP B 1 184 ? 127.214 110.627 94.113  1.00 42.97  ? 204 ASP B CA  1 
ATOM   7258  C C   . ASP B 1 184 ? 128.469 109.879 94.553  1.00 43.21  ? 204 ASP B C   1 
ATOM   7259  O O   . ASP B 1 184 ? 128.531 109.409 95.688  1.00 44.93  ? 204 ASP B O   1 
ATOM   7260  C CB  . ASP B 1 184 ? 126.290 109.723 93.300  1.00 43.78  ? 204 ASP B CB  1 
ATOM   7261  C CG  . ASP B 1 184 ? 124.924 110.333 93.057  1.00 44.88  ? 204 ASP B CG  1 
ATOM   7262  O OD1 . ASP B 1 184 ? 124.693 111.459 93.538  1.00 45.38  ? 204 ASP B OD1 1 
ATOM   7263  O OD2 . ASP B 1 184 ? 124.102 109.674 92.398  1.00 44.45  ? 204 ASP B OD2 1 
ATOM   7264  N N   . ILE B 1 185 ? 129.464 109.782 93.663  1.00 42.92  ? 205 ILE B N   1 
ATOM   7265  C CA  . ILE B 1 185 ? 130.692 109.075 93.985  1.00 42.70  ? 205 ILE B CA  1 
ATOM   7266  C C   . ILE B 1 185 ? 131.409 109.801 95.120  1.00 43.88  ? 205 ILE B C   1 
ATOM   7267  O O   . ILE B 1 185 ? 131.917 109.154 96.035  1.00 44.93  ? 205 ILE B O   1 
ATOM   7268  C CB  . ILE B 1 185 ? 131.608 108.919 92.757  1.00 42.28  ? 205 ILE B CB  1 
ATOM   7269  C CG1 . ILE B 1 185 ? 130.937 108.127 91.635  1.00 42.64  ? 205 ILE B CG1 1 
ATOM   7270  C CG2 . ILE B 1 185 ? 132.931 108.281 93.161  1.00 41.84  ? 205 ILE B CG2 1 
ATOM   7271  C CD1 . ILE B 1 185 ? 131.655 108.230 90.316  1.00 42.67  ? 205 ILE B CD1 1 
ATOM   7272  N N   . VAL B 1 186 ? 131.459 111.136 95.057  1.00 45.73  ? 206 VAL B N   1 
ATOM   7273  C CA  . VAL B 1 186 ? 132.213 111.876 96.055  1.00 48.20  ? 206 VAL B CA  1 
ATOM   7274  C C   . VAL B 1 186 ? 131.489 111.816 97.398  1.00 51.59  ? 206 VAL B C   1 
ATOM   7275  O O   . VAL B 1 186 ? 132.148 111.707 98.428  1.00 53.61  ? 206 VAL B O   1 
ATOM   7276  C CB  . VAL B 1 186 ? 132.549 113.321 95.640  1.00 48.16  ? 206 VAL B CB  1 
ATOM   7277  C CG1 . VAL B 1 186 ? 133.462 113.354 94.427  1.00 48.37  ? 206 VAL B CG1 1 
ATOM   7278  C CG2 . VAL B 1 186 ? 131.322 114.182 95.412  1.00 48.34  ? 206 VAL B CG2 1 
ATOM   7279  N N   . LYS B 1 187 ? 130.151 111.849 97.397  1.00 54.38  ? 207 LYS B N   1 
ATOM   7280  C CA  . LYS B 1 187 ? 129.415 111.845 98.653  1.00 57.11  ? 207 LYS B CA  1 
ATOM   7281  C C   . LYS B 1 187 ? 129.419 110.447 99.275  1.00 58.44  ? 207 LYS B C   1 
ATOM   7282  O O   . LYS B 1 187 ? 129.299 110.324 100.492 1.00 59.93  ? 207 LYS B O   1 
ATOM   7283  C CB  . LYS B 1 187 ? 127.977 112.344 98.472  1.00 58.98  ? 207 LYS B CB  1 
ATOM   7284  C CG  . LYS B 1 187 ? 126.951 111.279 98.113  1.00 61.86  ? 207 LYS B CG  1 
ATOM   7285  C CD  . LYS B 1 187 ? 125.521 111.719 98.313  1.00 64.36  ? 207 LYS B CD  1 
ATOM   7286  C CE  . LYS B 1 187 ? 125.047 112.693 97.257  1.00 66.19  ? 207 LYS B CE  1 
ATOM   7287  N NZ  . LYS B 1 187 ? 123.571 112.849 97.283  1.00 67.15  ? 207 LYS B NZ  1 
ATOM   7288  N N   . ARG B 1 188 ? 129.524 109.399 98.447  1.00 58.71  ? 208 ARG B N   1 
ATOM   7289  C CA  . ARG B 1 188 ? 129.490 108.036 98.953  1.00 60.36  ? 208 ARG B CA  1 
ATOM   7290  C C   . ARG B 1 188 ? 130.714 107.756 99.822  1.00 62.90  ? 208 ARG B C   1 
ATOM   7291  O O   . ARG B 1 188 ? 130.623 106.979 100.769 1.00 65.81  ? 208 ARG B O   1 
ATOM   7292  C CB  . ARG B 1 188 ? 129.417 107.017 97.814  1.00 61.06  ? 208 ARG B CB  1 
ATOM   7293  C CG  . ARG B 1 188 ? 129.090 105.610 98.286  1.00 62.64  ? 208 ARG B CG  1 
ATOM   7294  C CD  . ARG B 1 188 ? 128.930 104.653 97.118  1.00 63.96  ? 208 ARG B CD  1 
ATOM   7295  N NE  . ARG B 1 188 ? 128.181 103.450 97.462  1.00 65.21  ? 208 ARG B NE  1 
ATOM   7296  C CZ  . ARG B 1 188 ? 128.616 102.202 97.307  1.00 67.02  ? 208 ARG B CZ  1 
ATOM   7297  N NH1 . ARG B 1 188 ? 129.849 101.962 96.897  1.00 67.49  ? 208 ARG B NH1 1 
ATOM   7298  N NH2 . ARG B 1 188 ? 127.811 101.186 97.574  1.00 67.81  ? 208 ARG B NH2 1 
ATOM   7299  N N   . TYR B 1 189 ? 131.847 108.396 99.504  1.00 64.06  ? 209 TYR B N   1 
ATOM   7300  C CA  . TYR B 1 189 ? 133.087 108.190 100.234 1.00 66.68  ? 209 TYR B CA  1 
ATOM   7301  C C   . TYR B 1 189 ? 133.414 109.380 101.133 1.00 68.14  ? 209 TYR B C   1 
ATOM   7302  O O   . TYR B 1 189 ? 134.546 109.511 101.592 1.00 67.44  ? 209 TYR B O   1 
ATOM   7303  C CB  . TYR B 1 189 ? 134.219 107.903 99.245  1.00 68.28  ? 209 TYR B CB  1 
ATOM   7304  C CG  . TYR B 1 189 ? 134.083 106.563 98.572  1.00 70.81  ? 209 TYR B CG  1 
ATOM   7305  C CD1 . TYR B 1 189 ? 133.899 105.416 99.328  1.00 73.76  ? 209 TYR B CD1 1 
ATOM   7306  C CD2 . TYR B 1 189 ? 134.147 106.429 97.193  1.00 71.94  ? 209 TYR B CD2 1 
ATOM   7307  C CE1 . TYR B 1 189 ? 133.776 104.171 98.734  1.00 75.52  ? 209 TYR B CE1 1 
ATOM   7308  C CE2 . TYR B 1 189 ? 134.025 105.191 96.584  1.00 73.46  ? 209 TYR B CE2 1 
ATOM   7309  C CZ  . TYR B 1 189 ? 133.840 104.058 97.357  1.00 74.99  ? 209 TYR B CZ  1 
ATOM   7310  O OH  . TYR B 1 189 ? 133.722 102.819 96.780  1.00 75.81  ? 209 TYR B OH  1 
ATOM   7311  N N   . ASN B 1 190 ? 132.406 110.219 101.410 1.00 72.33  ? 210 ASN B N   1 
ATOM   7312  C CA  . ASN B 1 190 ? 132.503 111.302 102.381 1.00 77.25  ? 210 ASN B CA  1 
ATOM   7313  C C   . ASN B 1 190 ? 133.663 112.231 102.026 1.00 73.29  ? 210 ASN B C   1 
ATOM   7314  O O   . ASN B 1 190 ? 134.224 112.889 102.898 1.00 73.58  ? 210 ASN B O   1 
ATOM   7315  C CB  . ASN B 1 190 ? 132.640 110.798 103.823 1.00 84.34  ? 210 ASN B CB  1 
ATOM   7316  C CG  . ASN B 1 190 ? 131.567 109.811 104.235 1.00 92.28  ? 210 ASN B CG  1 
ATOM   7317  O OD1 . ASN B 1 190 ? 130.390 110.054 103.944 1.00 93.60  ? 210 ASN B OD1 1 
ATOM   7318  N ND2 . ASN B 1 190 ? 132.037 108.741 104.890 1.00 100.15 ? 210 ASN B ND2 1 
ATOM   7319  N N   . TRP B 1 191 ? 134.011 112.293 100.736 1.00 68.38  ? 211 TRP B N   1 
ATOM   7320  C CA  . TRP B 1 191 ? 134.942 113.296 100.256 1.00 64.36  ? 211 TRP B CA  1 
ATOM   7321  C C   . TRP B 1 191 ? 134.239 114.643 100.306 1.00 62.55  ? 211 TRP B C   1 
ATOM   7322  O O   . TRP B 1 191 ? 133.285 114.875 99.564  1.00 63.96  ? 211 TRP B O   1 
ATOM   7323  C CB  . TRP B 1 191 ? 135.427 112.967 98.842  1.00 63.09  ? 211 TRP B CB  1 
ATOM   7324  C CG  . TRP B 1 191 ? 136.257 111.728 98.769  1.00 61.56  ? 211 TRP B CG  1 
ATOM   7325  C CD1 . TRP B 1 191 ? 137.097 111.247 99.729  1.00 62.01  ? 211 TRP B CD1 1 
ATOM   7326  C CD2 . TRP B 1 191 ? 136.361 110.829 97.656  1.00 59.75  ? 211 TRP B CD2 1 
ATOM   7327  N NE1 . TRP B 1 191 ? 137.699 110.097 99.305  1.00 61.09  ? 211 TRP B NE1 1 
ATOM   7328  C CE2 . TRP B 1 191 ? 137.270 109.819 98.034  1.00 59.54  ? 211 TRP B CE2 1 
ATOM   7329  C CE3 . TRP B 1 191 ? 135.783 110.779 96.383  1.00 59.52  ? 211 TRP B CE3 1 
ATOM   7330  C CZ2 . TRP B 1 191 ? 137.609 108.772 97.183  1.00 59.84  ? 211 TRP B CZ2 1 
ATOM   7331  C CZ3 . TRP B 1 191 ? 136.115 109.737 95.545  1.00 60.29  ? 211 TRP B CZ3 1 
ATOM   7332  C CH2 . TRP B 1 191 ? 137.015 108.747 95.944  1.00 60.18  ? 211 TRP B CH2 1 
ATOM   7333  N N   . THR B 1 192 ? 134.690 115.501 101.225 1.00 59.59  ? 212 THR B N   1 
ATOM   7334  C CA  . THR B 1 192 ? 134.044 116.781 101.438 1.00 57.77  ? 212 THR B CA  1 
ATOM   7335  C C   . THR B 1 192 ? 134.907 117.902 100.872 1.00 54.28  ? 212 THR B C   1 
ATOM   7336  O O   . THR B 1 192 ? 134.381 118.768 100.179 1.00 55.23  ? 212 THR B O   1 
ATOM   7337  C CB  . THR B 1 192 ? 133.707 117.024 102.913 1.00 59.80  ? 212 THR B CB  1 
ATOM   7338  O OG1 . THR B 1 192 ? 133.132 115.843 103.473 1.00 59.74  ? 212 THR B OG1 1 
ATOM   7339  C CG2 . THR B 1 192 ? 132.735 118.170 103.073 1.00 60.55  ? 212 THR B CG2 1 
ATOM   7340  N N   . TYR B 1 193 ? 136.216 117.879 101.152 1.00 51.71  ? 213 TYR B N   1 
ATOM   7341  C CA  . TYR B 1 193 ? 137.105 118.941 100.710 1.00 50.26  ? 213 TYR B CA  1 
ATOM   7342  C C   . TYR B 1 193 ? 137.915 118.475 99.502  1.00 49.10  ? 213 TYR B C   1 
ATOM   7343  O O   . TYR B 1 193 ? 139.017 117.953 99.651  1.00 50.11  ? 213 TYR B O   1 
ATOM   7344  C CB  . TYR B 1 193 ? 138.015 119.370 101.861 1.00 50.98  ? 213 TYR B CB  1 
ATOM   7345  C CG  . TYR B 1 193 ? 138.775 120.651 101.628 1.00 50.52  ? 213 TYR B CG  1 
ATOM   7346  C CD1 . TYR B 1 193 ? 138.115 121.866 101.549 1.00 49.87  ? 213 TYR B CD1 1 
ATOM   7347  C CD2 . TYR B 1 193 ? 140.156 120.657 101.526 1.00 50.89  ? 213 TYR B CD2 1 
ATOM   7348  C CE1 . TYR B 1 193 ? 138.802 123.052 101.341 1.00 50.46  ? 213 TYR B CE1 1 
ATOM   7349  C CE2 . TYR B 1 193 ? 140.861 121.834 101.330 1.00 51.25  ? 213 TYR B CE2 1 
ATOM   7350  C CZ  . TYR B 1 193 ? 140.182 123.037 101.240 1.00 51.20  ? 213 TYR B CZ  1 
ATOM   7351  O OH  . TYR B 1 193 ? 140.879 124.206 101.044 1.00 51.96  ? 213 TYR B OH  1 
ATOM   7352  N N   . VAL B 1 194 ? 137.354 118.689 98.307  1.00 47.11  ? 214 VAL B N   1 
ATOM   7353  C CA  . VAL B 1 194 ? 137.990 118.292 97.063  1.00 45.00  ? 214 VAL B CA  1 
ATOM   7354  C C   . VAL B 1 194 ? 138.456 119.540 96.323  1.00 42.31  ? 214 VAL B C   1 
ATOM   7355  O O   . VAL B 1 194 ? 137.982 120.640 96.595  1.00 42.55  ? 214 VAL B O   1 
ATOM   7356  C CB  . VAL B 1 194 ? 137.038 117.460 96.183  1.00 45.40  ? 214 VAL B CB  1 
ATOM   7357  C CG1 . VAL B 1 194 ? 136.626 116.171 96.873  1.00 45.44  ? 214 VAL B CG1 1 
ATOM   7358  C CG2 . VAL B 1 194 ? 135.810 118.252 95.753  1.00 45.55  ? 214 VAL B CG2 1 
ATOM   7359  N N   . SER B 1 195 ? 139.384 119.342 95.382  1.00 39.75  ? 215 SER B N   1 
ATOM   7360  C CA  . SER B 1 195 ? 139.802 120.390 94.466  1.00 38.32  ? 215 SER B CA  1 
ATOM   7361  C C   . SER B 1 195 ? 139.332 120.032 93.061  1.00 37.14  ? 215 SER B C   1 
ATOM   7362  O O   . SER B 1 195 ? 139.339 118.865 92.688  1.00 37.95  ? 215 SER B O   1 
ATOM   7363  C CB  . SER B 1 195 ? 141.294 120.621 94.519  1.00 38.46  ? 215 SER B CB  1 
ATOM   7364  O OG  . SER B 1 195 ? 142.019 119.502 94.034  1.00 38.90  ? 215 SER B OG  1 
ATOM   7365  N N   . ALA B 1 196 ? 138.945 121.045 92.279  1.00 35.34  ? 216 ALA B N   1 
ATOM   7366  C CA  . ALA B 1 196 ? 138.338 120.821 90.978  1.00 33.94  ? 216 ALA B CA  1 
ATOM   7367  C C   . ALA B 1 196 ? 139.244 121.341 89.866  1.00 32.69  ? 216 ALA B C   1 
ATOM   7368  O O   . ALA B 1 196 ? 139.790 122.435 89.977  1.00 33.94  ? 216 ALA B O   1 
ATOM   7369  C CB  . ALA B 1 196 ? 136.984 121.482 90.936  1.00 34.36  ? 216 ALA B CB  1 
ATOM   7370  N N   . VAL B 1 197 ? 139.386 120.540 88.802  1.00 31.09  ? 217 VAL B N   1 
ATOM   7371  C CA  . VAL B 1 197 ? 140.036 120.967 87.573  1.00 30.03  ? 217 VAL B CA  1 
ATOM   7372  C C   . VAL B 1 197 ? 139.104 120.650 86.409  1.00 30.06  ? 217 VAL B C   1 
ATOM   7373  O O   . VAL B 1 197 ? 138.512 119.581 86.371  1.00 30.92  ? 217 VAL B O   1 
ATOM   7374  C CB  . VAL B 1 197 ? 141.403 120.287 87.375  1.00 29.39  ? 217 VAL B CB  1 
ATOM   7375  C CG1 . VAL B 1 197 ? 142.020 120.616 86.025  1.00 29.14  ? 217 VAL B CG1 1 
ATOM   7376  C CG2 . VAL B 1 197 ? 142.370 120.647 88.485  1.00 29.74  ? 217 VAL B CG2 1 
ATOM   7377  N N   . HIS B 1 198 ? 138.987 121.584 85.461  1.00 29.55  ? 218 HIS B N   1 
ATOM   7378  C CA  . HIS B 1 198 ? 138.185 121.364 84.271  1.00 29.29  ? 218 HIS B CA  1 
ATOM   7379  C C   . HIS B 1 198 ? 138.896 121.979 83.072  1.00 29.00  ? 218 HIS B C   1 
ATOM   7380  O O   . HIS B 1 198 ? 139.536 123.016 83.198  1.00 29.95  ? 218 HIS B O   1 
ATOM   7381  C CB  . HIS B 1 198 ? 136.777 121.950 84.449  1.00 29.42  ? 218 HIS B CB  1 
ATOM   7382  C CG  . HIS B 1 198 ? 136.716 123.437 84.395  1.00 30.09  ? 218 HIS B CG  1 
ATOM   7383  N ND1 . HIS B 1 198 ? 136.675 124.154 83.219  1.00 30.55  ? 218 HIS B ND1 1 
ATOM   7384  C CD2 . HIS B 1 198 ? 136.657 124.339 85.376  1.00 30.91  ? 218 HIS B CD2 1 
ATOM   7385  C CE1 . HIS B 1 198 ? 136.617 125.449 83.496  1.00 31.02  ? 218 HIS B CE1 1 
ATOM   7386  N NE2 . HIS B 1 198 ? 136.609 125.585 84.802  1.00 31.17  ? 218 HIS B NE2 1 
ATOM   7387  N N   . THR B 1 199 ? 138.769 121.336 81.910  1.00 28.83  ? 219 THR B N   1 
ATOM   7388  C CA  . THR B 1 199 ? 139.394 121.834 80.699  1.00 29.02  ? 219 THR B CA  1 
ATOM   7389  C C   . THR B 1 199 ? 138.656 123.078 80.217  1.00 30.50  ? 219 THR B C   1 
ATOM   7390  O O   . THR B 1 199 ? 137.434 123.142 80.293  1.00 31.00  ? 219 THR B O   1 
ATOM   7391  C CB  . THR B 1 199 ? 139.404 120.774 79.594  1.00 28.55  ? 219 THR B CB  1 
ATOM   7392  O OG1 . THR B 1 199 ? 140.035 119.608 80.111  1.00 28.61  ? 219 THR B OG1 1 
ATOM   7393  C CG2 . THR B 1 199 ? 140.138 121.225 78.353  1.00 28.56  ? 219 THR B CG2 1 
ATOM   7394  N N   . GLU B 1 200 ? 139.414 124.052 79.705  1.00 32.68  ? 220 GLU B N   1 
ATOM   7395  C CA  . GLU B 1 200 ? 138.829 125.224 79.081  1.00 34.84  ? 220 GLU B CA  1 
ATOM   7396  C C   . GLU B 1 200 ? 138.002 124.783 77.880  1.00 35.49  ? 220 GLU B C   1 
ATOM   7397  O O   . GLU B 1 200 ? 138.438 123.950 77.088  1.00 35.74  ? 220 GLU B O   1 
ATOM   7398  C CB  . GLU B 1 200 ? 139.895 126.213 78.607  1.00 36.91  ? 220 GLU B CB  1 
ATOM   7399  C CG  . GLU B 1 200 ? 139.415 127.648 78.670  1.00 39.32  ? 220 GLU B CG  1 
ATOM   7400  C CD  . GLU B 1 200 ? 139.337 128.191 80.083  1.00 41.33  ? 220 GLU B CD  1 
ATOM   7401  O OE1 . GLU B 1 200 ? 138.395 128.959 80.384  1.00 42.17  ? 220 GLU B OE1 1 
ATOM   7402  O OE2 . GLU B 1 200 ? 140.202 127.797 80.889  1.00 42.36  ? 220 GLU B OE2 1 
ATOM   7403  N N   . GLY B 1 201 ? 136.811 125.367 77.748  1.00 35.99  ? 221 GLY B N   1 
ATOM   7404  C CA  . GLY B 1 201 ? 135.917 125.041 76.654  1.00 36.70  ? 221 GLY B CA  1 
ATOM   7405  C C   . GLY B 1 201 ? 134.466 125.114 77.110  1.00 37.03  ? 221 GLY B C   1 
ATOM   7406  O O   . GLY B 1 201 ? 134.108 125.994 77.893  1.00 37.86  ? 221 GLY B O   1 
ATOM   7407  N N   . ASN B 1 202 ? 133.647 124.174 76.624  1.00 36.60  ? 222 ASN B N   1 
ATOM   7408  C CA  . ASN B 1 202 ? 132.252 124.126 77.021  1.00 36.54  ? 222 ASN B CA  1 
ATOM   7409  C C   . ASN B 1 202 ? 131.975 122.862 77.825  1.00 36.03  ? 222 ASN B C   1 
ATOM   7410  O O   . ASN B 1 202 ? 131.289 122.939 78.841  1.00 36.59  ? 222 ASN B O   1 
ATOM   7411  C CB  . ASN B 1 202 ? 131.306 124.256 75.830  1.00 37.31  ? 222 ASN B CB  1 
ATOM   7412  C CG  . ASN B 1 202 ? 129.870 124.471 76.257  1.00 38.80  ? 222 ASN B CG  1 
ATOM   7413  O OD1 . ASN B 1 202 ? 128.950 123.990 75.604  1.00 39.32  ? 222 ASN B OD1 1 
ATOM   7414  N ND2 . ASN B 1 202 ? 129.666 125.190 77.350  1.00 39.78  ? 222 ASN B ND2 1 
ATOM   7415  N N   . TYR B 1 203 ? 132.515 121.726 77.370  1.00 36.02  ? 223 TYR B N   1 
ATOM   7416  C CA  . TYR B 1 203 ? 132.361 120.464 78.076  1.00 35.86  ? 223 TYR B CA  1 
ATOM   7417  C C   . TYR B 1 203 ? 132.849 120.614 79.514  1.00 35.82  ? 223 TYR B C   1 
ATOM   7418  O O   . TYR B 1 203 ? 132.094 120.371 80.455  1.00 36.50  ? 223 TYR B O   1 
ATOM   7419  C CB  . TYR B 1 203 ? 133.098 119.348 77.332  1.00 35.66  ? 223 TYR B CB  1 
ATOM   7420  C CG  . TYR B 1 203 ? 133.310 118.094 78.138  1.00 35.69  ? 223 TYR B CG  1 
ATOM   7421  C CD1 . TYR B 1 203 ? 132.241 117.359 78.624  1.00 35.78  ? 223 TYR B CD1 1 
ATOM   7422  C CD2 . TYR B 1 203 ? 134.589 117.653 78.434  1.00 36.18  ? 223 TYR B CD2 1 
ATOM   7423  C CE1 . TYR B 1 203 ? 132.435 116.221 79.386  1.00 36.13  ? 223 TYR B CE1 1 
ATOM   7424  C CE2 . TYR B 1 203 ? 134.802 116.512 79.187  1.00 36.28  ? 223 TYR B CE2 1 
ATOM   7425  C CZ  . TYR B 1 203 ? 133.721 115.794 79.663  1.00 36.26  ? 223 TYR B CZ  1 
ATOM   7426  O OH  . TYR B 1 203 ? 133.935 114.669 80.413  1.00 36.56  ? 223 TYR B OH  1 
ATOM   7427  N N   . GLY B 1 204 ? 134.102 121.053 79.670  1.00 35.54  ? 224 GLY B N   1 
ATOM   7428  C CA  . GLY B 1 204 ? 134.672 121.279 80.986  1.00 35.66  ? 224 GLY B CA  1 
ATOM   7429  C C   . GLY B 1 204 ? 133.899 122.329 81.781  1.00 36.15  ? 224 GLY B C   1 
ATOM   7430  O O   . GLY B 1 204 ? 133.570 122.105 82.942  1.00 36.44  ? 224 GLY B O   1 
ATOM   7431  N N   . GLU B 1 205 ? 133.605 123.463 81.138  1.00 37.99  ? 225 GLU B N   1 
ATOM   7432  C CA  . GLU B 1 205 ? 133.036 124.613 81.820  1.00 40.02  ? 225 GLU B CA  1 
ATOM   7433  C C   . GLU B 1 205 ? 131.637 124.269 82.332  1.00 39.24  ? 225 GLU B C   1 
ATOM   7434  O O   . GLU B 1 205 ? 131.345 124.461 83.512  1.00 39.96  ? 225 GLU B O   1 
ATOM   7435  C CB  . GLU B 1 205 ? 133.020 125.816 80.875  1.00 43.48  ? 225 GLU B CB  1 
ATOM   7436  C CG  . GLU B 1 205 ? 133.098 127.167 81.568  1.00 47.26  ? 225 GLU B CG  1 
ATOM   7437  C CD  . GLU B 1 205 ? 131.950 127.497 82.508  1.00 50.74  ? 225 GLU B CD  1 
ATOM   7438  O OE1 . GLU B 1 205 ? 130.798 127.143 82.181  1.00 52.18  ? 225 GLU B OE1 1 
ATOM   7439  O OE2 . GLU B 1 205 ? 132.205 128.143 83.549  1.00 51.82  ? 225 GLU B OE2 1 
ATOM   7440  N N   . SER B 1 206 ? 130.784 123.751 81.440  1.00 38.88  ? 226 SER B N   1 
ATOM   7441  C CA  . SER B 1 206 ? 129.405 123.449 81.794  1.00 38.87  ? 226 SER B CA  1 
ATOM   7442  C C   . SER B 1 206 ? 129.370 122.310 82.809  1.00 37.97  ? 226 SER B C   1 
ATOM   7443  O O   . SER B 1 206 ? 128.605 122.361 83.768  1.00 38.21  ? 226 SER B O   1 
ATOM   7444  C CB  . SER B 1 206 ? 128.574 123.111 80.583  1.00 39.47  ? 226 SER B CB  1 
ATOM   7445  O OG  . SER B 1 206 ? 128.518 121.706 80.380  1.00 39.58  ? 226 SER B OG  1 
ATOM   7446  N N   . GLY B 1 207 ? 130.195 121.285 82.580  1.00 37.41  ? 227 GLY B N   1 
ATOM   7447  C CA  . GLY B 1 207 ? 130.279 120.156 83.488  1.00 37.37  ? 227 GLY B CA  1 
ATOM   7448  C C   . GLY B 1 207 ? 130.649 120.588 84.903  1.00 37.60  ? 227 GLY B C   1 
ATOM   7449  O O   . GLY B 1 207 ? 130.025 120.154 85.868  1.00 38.40  ? 227 GLY B O   1 
ATOM   7450  N N   . MET B 1 208 ? 131.642 121.476 85.014  1.00 38.01  ? 228 MET B N   1 
ATOM   7451  C CA  . MET B 1 208 ? 132.148 121.875 86.314  1.00 38.48  ? 228 MET B CA  1 
ATOM   7452  C C   . MET B 1 208 ? 131.162 122.834 86.980  1.00 40.06  ? 228 MET B C   1 
ATOM   7453  O O   . MET B 1 208 ? 131.064 122.845 88.203  1.00 41.99  ? 228 MET B O   1 
ATOM   7454  C CB  . MET B 1 208 ? 133.537 122.517 86.199  1.00 38.68  ? 228 MET B CB  1 
ATOM   7455  C CG  . MET B 1 208 ? 134.209 122.823 87.533  1.00 39.27  ? 228 MET B CG  1 
ATOM   7456  S SD  . MET B 1 208 ? 134.053 121.474 88.744  1.00 40.31  ? 228 MET B SD  1 
ATOM   7457  C CE  . MET B 1 208 ? 135.052 120.226 87.942  1.00 39.47  ? 228 MET B CE  1 
ATOM   7458  N N   . GLU B 1 209 ? 130.422 123.625 86.192  1.00 42.02  ? 229 GLU B N   1 
ATOM   7459  C CA  . GLU B 1 209 ? 129.396 124.480 86.767  1.00 43.94  ? 229 GLU B CA  1 
ATOM   7460  C C   . GLU B 1 209 ? 128.295 123.620 87.381  1.00 43.38  ? 229 GLU B C   1 
ATOM   7461  O O   . GLU B 1 209 ? 127.854 123.892 88.493  1.00 43.80  ? 229 GLU B O   1 
ATOM   7462  C CB  . GLU B 1 209 ? 128.841 125.457 85.730  1.00 46.46  ? 229 GLU B CB  1 
ATOM   7463  C CG  . GLU B 1 209 ? 129.844 126.507 85.292  1.00 49.24  ? 229 GLU B CG  1 
ATOM   7464  C CD  . GLU B 1 209 ? 130.912 126.856 86.318  1.00 52.18  ? 229 GLU B CD  1 
ATOM   7465  O OE1 . GLU B 1 209 ? 130.548 127.238 87.453  1.00 53.03  ? 229 GLU B OE1 1 
ATOM   7466  O OE2 . GLU B 1 209 ? 132.108 126.745 85.981  1.00 53.11  ? 229 GLU B OE2 1 
ATOM   7467  N N   . ALA B 1 210 ? 127.881 122.568 86.665  1.00 43.12  ? 230 ALA B N   1 
ATOM   7468  C CA  . ALA B 1 210 ? 126.858 121.660 87.159  1.00 42.96  ? 230 ALA B CA  1 
ATOM   7469  C C   . ALA B 1 210 ? 127.344 120.974 88.430  1.00 43.06  ? 230 ALA B C   1 
ATOM   7470  O O   . ALA B 1 210 ? 126.602 120.908 89.412  1.00 45.11  ? 230 ALA B O   1 
ATOM   7471  C CB  . ALA B 1 210 ? 126.493 120.646 86.104  1.00 43.07  ? 230 ALA B CB  1 
ATOM   7472  N N   . PHE B 1 211 ? 128.591 120.481 88.401  1.00 43.25  ? 231 PHE B N   1 
ATOM   7473  C CA  . PHE B 1 211 ? 129.168 119.779 89.537  1.00 44.17  ? 231 PHE B CA  1 
ATOM   7474  C C   . PHE B 1 211 ? 129.223 120.706 90.748  1.00 45.72  ? 231 PHE B C   1 
ATOM   7475  O O   . PHE B 1 211 ? 128.868 120.301 91.853  1.00 46.39  ? 231 PHE B O   1 
ATOM   7476  C CB  . PHE B 1 211 ? 130.572 119.256 89.221  1.00 44.06  ? 231 PHE B CB  1 
ATOM   7477  C CG  . PHE B 1 211 ? 131.263 118.598 90.390  1.00 43.83  ? 231 PHE B CG  1 
ATOM   7478  C CD1 . PHE B 1 211 ? 130.901 117.328 90.815  1.00 43.21  ? 231 PHE B CD1 1 
ATOM   7479  C CD2 . PHE B 1 211 ? 132.250 119.271 91.095  1.00 43.87  ? 231 PHE B CD2 1 
ATOM   7480  C CE1 . PHE B 1 211 ? 131.526 116.739 91.905  1.00 42.59  ? 231 PHE B CE1 1 
ATOM   7481  C CE2 . PHE B 1 211 ? 132.878 118.678 92.180  1.00 43.40  ? 231 PHE B CE2 1 
ATOM   7482  C CZ  . PHE B 1 211 ? 132.520 117.410 92.578  1.00 42.69  ? 231 PHE B CZ  1 
ATOM   7483  N N   . LYS B 1 212 ? 129.671 121.945 90.526  1.00 48.33  ? 232 LYS B N   1 
ATOM   7484  C CA  . LYS B 1 212 ? 129.822 122.912 91.598  1.00 50.76  ? 232 LYS B CA  1 
ATOM   7485  C C   . LYS B 1 212 ? 128.462 123.197 92.228  1.00 51.94  ? 232 LYS B C   1 
ATOM   7486  O O   . LYS B 1 212 ? 128.338 123.197 93.451  1.00 53.00  ? 232 LYS B O   1 
ATOM   7487  C CB  . LYS B 1 212 ? 130.452 124.194 91.052  1.00 52.24  ? 232 LYS B CB  1 
ATOM   7488  C CG  . LYS B 1 212 ? 131.152 125.074 92.076  1.00 53.87  ? 232 LYS B CG  1 
ATOM   7489  C CD  . LYS B 1 212 ? 132.134 126.037 91.452  1.00 55.31  ? 232 LYS B CD  1 
ATOM   7490  C CE  . LYS B 1 212 ? 133.169 125.360 90.578  1.00 55.52  ? 232 LYS B CE  1 
ATOM   7491  N NZ  . LYS B 1 212 ? 133.793 126.326 89.646  1.00 56.49  ? 232 LYS B NZ  1 
ATOM   7492  N N   . ASP B 1 213 ? 127.448 123.417 91.383  1.00 53.98  ? 233 ASP B N   1 
ATOM   7493  C CA  . ASP B 1 213 ? 126.112 123.731 91.857  1.00 57.13  ? 233 ASP B CA  1 
ATOM   7494  C C   . ASP B 1 213 ? 125.609 122.607 92.756  1.00 56.00  ? 233 ASP B C   1 
ATOM   7495  O O   . ASP B 1 213 ? 125.301 122.846 93.924  1.00 57.80  ? 233 ASP B O   1 
ATOM   7496  C CB  . ASP B 1 213 ? 125.152 123.992 90.693  1.00 61.22  ? 233 ASP B CB  1 
ATOM   7497  C CG  . ASP B 1 213 ? 125.449 125.280 89.940  1.00 65.11  ? 233 ASP B CG  1 
ATOM   7498  O OD1 . ASP B 1 213 ? 126.242 126.094 90.466  1.00 66.74  ? 233 ASP B OD1 1 
ATOM   7499  O OD2 . ASP B 1 213 ? 124.919 125.443 88.818  1.00 66.33  ? 233 ASP B OD2 1 
ATOM   7500  N N   . MET B 1 214 ? 125.548 121.384 92.220  1.00 55.01  ? 234 MET B N   1 
ATOM   7501  C CA  . MET B 1 214 ? 124.892 120.306 92.946  1.00 55.40  ? 234 MET B CA  1 
ATOM   7502  C C   . MET B 1 214 ? 125.740 119.853 94.133  1.00 56.82  ? 234 MET B C   1 
ATOM   7503  O O   . MET B 1 214 ? 125.179 119.448 95.153  1.00 58.65  ? 234 MET B O   1 
ATOM   7504  C CB  . MET B 1 214 ? 124.531 119.099 92.078  1.00 54.66  ? 234 MET B CB  1 
ATOM   7505  C CG  . MET B 1 214 ? 125.579 118.664 91.089  1.00 54.34  ? 234 MET B CG  1 
ATOM   7506  S SD  . MET B 1 214 ? 124.906 117.438 89.960  1.00 53.78  ? 234 MET B SD  1 
ATOM   7507  C CE  . MET B 1 214 ? 123.933 118.483 88.878  1.00 54.01  ? 234 MET B CE  1 
ATOM   7508  N N   . SER B 1 215 ? 127.067 120.013 94.049  1.00 57.62  ? 235 SER B N   1 
ATOM   7509  C CA  . SER B 1 215 ? 127.947 119.594 95.134  1.00 59.06  ? 235 SER B CA  1 
ATOM   7510  C C   . SER B 1 215 ? 127.826 120.557 96.315  1.00 60.79  ? 235 SER B C   1 
ATOM   7511  O O   . SER B 1 215 ? 127.666 120.120 97.455  1.00 62.06  ? 235 SER B O   1 
ATOM   7512  C CB  . SER B 1 215 ? 129.371 119.474 94.667  1.00 59.69  ? 235 SER B CB  1 
ATOM   7513  O OG  . SER B 1 215 ? 129.904 120.742 94.319  1.00 60.69  ? 235 SER B OG  1 
ATOM   7514  N N   . ALA B 1 216 ? 127.883 121.866 96.036  1.00 64.06  ? 236 ALA B N   1 
ATOM   7515  C CA  . ALA B 1 216 ? 127.717 122.871 97.075  1.00 68.16  ? 236 ALA B CA  1 
ATOM   7516  C C   . ALA B 1 216 ? 126.314 122.780 97.673  1.00 70.64  ? 236 ALA B C   1 
ATOM   7517  O O   . ALA B 1 216 ? 126.121 123.097 98.844  1.00 70.40  ? 236 ALA B O   1 
ATOM   7518  C CB  . ALA B 1 216 ? 127.993 124.249 96.525  1.00 69.28  ? 236 ALA B CB  1 
ATOM   7519  N N   . LYS B 1 217 ? 125.344 122.332 96.866  1.00 73.86  ? 237 LYS B N   1 
ATOM   7520  C CA  . LYS B 1 217 ? 123.981 122.139 97.330  1.00 76.83  ? 237 LYS B CA  1 
ATOM   7521  C C   . LYS B 1 217 ? 123.935 121.002 98.348  1.00 76.39  ? 237 LYS B C   1 
ATOM   7522  O O   . LYS B 1 217 ? 123.299 121.137 99.391  1.00 77.28  ? 237 LYS B O   1 
ATOM   7523  C CB  . LYS B 1 217 ? 123.044 121.859 96.150  1.00 80.17  ? 237 LYS B CB  1 
ATOM   7524  C CG  . LYS B 1 217 ? 121.560 121.821 96.489  1.00 84.10  ? 237 LYS B CG  1 
ATOM   7525  C CD  . LYS B 1 217 ? 120.693 121.532 95.288  1.00 87.88  ? 237 LYS B CD  1 
ATOM   7526  C CE  . LYS B 1 217 ? 120.725 122.646 94.263  1.00 90.06  ? 237 LYS B CE  1 
ATOM   7527  N NZ  . LYS B 1 217 ? 120.466 122.126 92.903  1.00 90.54  ? 237 LYS B NZ  1 
ATOM   7528  N N   . GLU B 1 218 ? 124.621 119.892 98.053  1.00 75.44  ? 238 GLU B N   1 
ATOM   7529  C CA  . GLU B 1 218 ? 124.502 118.703 98.885  1.00 74.86  ? 238 GLU B CA  1 
ATOM   7530  C C   . GLU B 1 218 ? 125.367 118.848 100.135 1.00 72.89  ? 238 GLU B C   1 
ATOM   7531  O O   . GLU B 1 218 ? 124.948 118.448 101.221 1.00 73.96  ? 238 GLU B O   1 
ATOM   7532  C CB  . GLU B 1 218 ? 124.847 117.448 98.085  1.00 76.40  ? 238 GLU B CB  1 
ATOM   7533  C CG  . GLU B 1 218 ? 124.646 116.162 98.868  1.00 78.75  ? 238 GLU B CG  1 
ATOM   7534  C CD  . GLU B 1 218 ? 125.839 115.665 99.670  1.00 81.47  ? 238 GLU B CD  1 
ATOM   7535  O OE1 . GLU B 1 218 ? 126.961 116.152 99.435  1.00 81.06  ? 238 GLU B OE1 1 
ATOM   7536  O OE2 . GLU B 1 218 ? 125.640 114.780 100.529 1.00 83.19  ? 238 GLU B OE2 1 
ATOM   7537  N N   . GLY B 1 219 ? 126.567 119.418 99.974  1.00 70.59  ? 239 GLY B N   1 
ATOM   7538  C CA  . GLY B 1 219 ? 127.475 119.626 101.093 1.00 69.68  ? 239 GLY B CA  1 
ATOM   7539  C C   . GLY B 1 219 ? 128.948 119.412 100.748 1.00 68.31  ? 239 GLY B C   1 
ATOM   7540  O O   . GLY B 1 219 ? 129.815 119.683 101.576 1.00 68.69  ? 239 GLY B O   1 
ATOM   7541  N N   . ILE B 1 220 ? 129.233 118.945 99.528  1.00 66.16  ? 240 ILE B N   1 
ATOM   7542  C CA  . ILE B 1 220 ? 130.600 118.831 99.046  1.00 64.18  ? 240 ILE B CA  1 
ATOM   7543  C C   . ILE B 1 220 ? 131.190 120.236 98.929  1.00 64.06  ? 240 ILE B C   1 
ATOM   7544  O O   . ILE B 1 220 ? 130.471 121.215 98.750  1.00 63.90  ? 240 ILE B O   1 
ATOM   7545  C CB  . ILE B 1 220 ? 130.662 118.071 97.705  1.00 63.57  ? 240 ILE B CB  1 
ATOM   7546  C CG1 . ILE B 1 220 ? 129.721 116.862 97.667  1.00 64.53  ? 240 ILE B CG1 1 
ATOM   7547  C CG2 . ILE B 1 220 ? 132.098 117.669 97.382  1.00 62.71  ? 240 ILE B CG2 1 
ATOM   7548  C CD1 . ILE B 1 220 ? 130.015 115.815 98.723  1.00 65.39  ? 240 ILE B CD1 1 
ATOM   7549  N N   . CYS B 1 221 ? 132.506 120.318 99.110  1.00 65.47  ? 241 CYS B N   1 
ATOM   7550  C CA  . CYS B 1 221 ? 133.224 121.578 99.179  1.00 67.76  ? 241 CYS B CA  1 
ATOM   7551  C C   . CYS B 1 221 ? 134.376 121.558 98.181  1.00 64.71  ? 241 CYS B C   1 
ATOM   7552  O O   . CYS B 1 221 ? 135.106 120.568 98.087  1.00 64.20  ? 241 CYS B O   1 
ATOM   7553  C CB  . CYS B 1 221 ? 133.769 121.810 100.582 1.00 74.61  ? 241 CYS B CB  1 
ATOM   7554  S SG  . CYS B 1 221 ? 132.469 122.107 101.809 1.00 86.94  ? 241 CYS B SG  1 
ATOM   7555  N N   . ILE B 1 222 ? 134.527 122.660 97.440  1.00 62.18  ? 242 ILE B N   1 
ATOM   7556  C CA  . ILE B 1 222 ? 135.600 122.778 96.470  1.00 59.90  ? 242 ILE B CA  1 
ATOM   7557  C C   . ILE B 1 222 ? 136.676 123.693 97.044  1.00 57.72  ? 242 ILE B C   1 
ATOM   7558  O O   . ILE B 1 222 ? 136.425 124.863 97.319  1.00 57.03  ? 242 ILE B O   1 
ATOM   7559  C CB  . ILE B 1 222 ? 135.074 123.262 95.105  1.00 58.57  ? 242 ILE B CB  1 
ATOM   7560  C CG1 . ILE B 1 222 ? 134.150 122.216 94.476  1.00 57.96  ? 242 ILE B CG1 1 
ATOM   7561  C CG2 . ILE B 1 222 ? 136.228 123.627 94.186  1.00 58.34  ? 242 ILE B CG2 1 
ATOM   7562  C CD1 . ILE B 1 222 ? 133.525 122.642 93.167  1.00 58.75  ? 242 ILE B CD1 1 
ATOM   7563  N N   . ALA B 1 223 ? 137.880 123.136 97.209  1.00 56.34  ? 243 ALA B N   1 
ATOM   7564  C CA  . ALA B 1 223 ? 139.021 123.881 97.712  1.00 56.21  ? 243 ALA B CA  1 
ATOM   7565  C C   . ALA B 1 223 ? 139.328 125.036 96.763  1.00 58.46  ? 243 ALA B C   1 
ATOM   7566  O O   . ALA B 1 223 ? 139.400 126.189 97.186  1.00 59.69  ? 243 ALA B O   1 
ATOM   7567  C CB  . ALA B 1 223 ? 140.208 122.964 97.865  1.00 55.27  ? 243 ALA B CB  1 
ATOM   7568  N N   . HIS B 1 224 ? 139.507 124.709 95.479  1.00 59.84  ? 244 HIS B N   1 
ATOM   7569  C CA  . HIS B 1 224 ? 139.762 125.714 94.461  1.00 60.86  ? 244 HIS B CA  1 
ATOM   7570  C C   . HIS B 1 224 ? 139.507 125.104 93.087  1.00 57.26  ? 244 HIS B C   1 
ATOM   7571  O O   . HIS B 1 224 ? 139.976 124.005 92.802  1.00 56.93  ? 244 HIS B O   1 
ATOM   7572  C CB  . HIS B 1 224 ? 141.190 126.257 94.577  1.00 64.71  ? 244 HIS B CB  1 
ATOM   7573  C CG  . HIS B 1 224 ? 141.316 127.684 94.156  1.00 71.61  ? 244 HIS B CG  1 
ATOM   7574  N ND1 . HIS B 1 224 ? 141.174 128.700 95.075  1.00 76.24  ? 244 HIS B ND1 1 
ATOM   7575  C CD2 . HIS B 1 224 ? 141.523 128.277 92.971  1.00 75.69  ? 244 HIS B CD2 1 
ATOM   7576  C CE1 . HIS B 1 224 ? 141.314 129.867 94.461  1.00 78.64  ? 244 HIS B CE1 1 
ATOM   7577  N NE2 . HIS B 1 224 ? 141.527 129.634 93.181  1.00 78.24  ? 244 HIS B NE2 1 
ATOM   7578  N N   . SER B 1 225 ? 138.757 125.827 92.249  1.00 54.77  ? 245 SER B N   1 
ATOM   7579  C CA  . SER B 1 225 ? 138.444 125.369 90.907  1.00 52.59  ? 245 SER B CA  1 
ATOM   7580  C C   . SER B 1 225 ? 139.462 125.951 89.932  1.00 50.12  ? 245 SER B C   1 
ATOM   7581  O O   . SER B 1 225 ? 139.596 127.170 89.835  1.00 50.90  ? 245 SER B O   1 
ATOM   7582  C CB  . SER B 1 225 ? 137.038 125.741 90.516  1.00 53.28  ? 245 SER B CB  1 
ATOM   7583  O OG  . SER B 1 225 ? 136.684 125.147 89.276  1.00 52.87  ? 245 SER B OG  1 
ATOM   7584  N N   . TYR B 1 226 ? 140.161 125.064 89.216  1.00 47.74  ? 246 TYR B N   1 
ATOM   7585  C CA  . TYR B 1 226 ? 141.154 125.465 88.239  1.00 46.98  ? 246 TYR B CA  1 
ATOM   7586  C C   . TYR B 1 226 ? 140.668 125.147 86.831  1.00 45.40  ? 246 TYR B C   1 
ATOM   7587  O O   . TYR B 1 226 ? 139.839 124.262 86.625  1.00 45.74  ? 246 TYR B O   1 
ATOM   7588  C CB  . TYR B 1 226 ? 142.476 124.760 88.528  1.00 47.97  ? 246 TYR B CB  1 
ATOM   7589  C CG  . TYR B 1 226 ? 143.052 125.074 89.884  1.00 49.98  ? 246 TYR B CG  1 
ATOM   7590  C CD1 . TYR B 1 226 ? 143.571 126.330 90.158  1.00 52.13  ? 246 TYR B CD1 1 
ATOM   7591  C CD2 . TYR B 1 226 ? 143.080 124.129 90.895  1.00 50.85  ? 246 TYR B CD2 1 
ATOM   7592  C CE1 . TYR B 1 226 ? 144.106 126.639 91.396  1.00 52.82  ? 246 TYR B CE1 1 
ATOM   7593  C CE2 . TYR B 1 226 ? 143.629 124.414 92.134  1.00 52.37  ? 246 TYR B CE2 1 
ATOM   7594  C CZ  . TYR B 1 226 ? 144.134 125.677 92.389  1.00 53.31  ? 246 TYR B CZ  1 
ATOM   7595  O OH  . TYR B 1 226 ? 144.676 125.973 93.615  1.00 54.92  ? 246 TYR B OH  1 
ATOM   7596  N N   . LYS B 1 227 ? 141.198 125.905 85.868  1.00 43.39  ? 247 LYS B N   1 
ATOM   7597  C CA  . LYS B 1 227 ? 140.900 125.700 84.463  1.00 41.90  ? 247 LYS B CA  1 
ATOM   7598  C C   . LYS B 1 227 ? 142.209 125.722 83.688  1.00 40.58  ? 247 LYS B C   1 
ATOM   7599  O O   . LYS B 1 227 ? 143.148 126.408 84.075  1.00 41.22  ? 247 LYS B O   1 
ATOM   7600  C CB  . LYS B 1 227 ? 139.943 126.776 83.953  1.00 42.66  ? 247 LYS B CB  1 
ATOM   7601  C CG  . LYS B 1 227 ? 140.488 128.196 84.005  1.00 44.30  ? 247 LYS B CG  1 
ATOM   7602  C CD  . LYS B 1 227 ? 139.479 129.252 83.602  1.00 45.60  ? 247 LYS B CD  1 
ATOM   7603  C CE  . LYS B 1 227 ? 138.120 129.102 84.258  1.00 46.75  ? 247 LYS B CE  1 
ATOM   7604  N NZ  . LYS B 1 227 ? 138.225 129.037 85.736  1.00 47.31  ? 247 LYS B NZ  1 
ATOM   7605  N N   . ILE B 1 228 ? 142.255 124.974 82.588  1.00 39.54  ? 248 ILE B N   1 
ATOM   7606  C CA  . ILE B 1 228 ? 143.464 124.874 81.791  1.00 39.62  ? 248 ILE B CA  1 
ATOM   7607  C C   . ILE B 1 228 ? 143.086 124.393 80.397  1.00 40.27  ? 248 ILE B C   1 
ATOM   7608  O O   . ILE B 1 228 ? 142.186 123.570 80.248  1.00 40.73  ? 248 ILE B O   1 
ATOM   7609  C CB  . ILE B 1 228 ? 144.496 123.941 82.455  1.00 39.92  ? 248 ILE B CB  1 
ATOM   7610  C CG1 . ILE B 1 228 ? 145.779 123.852 81.623  1.00 41.05  ? 248 ILE B CG1 1 
ATOM   7611  C CG2 . ILE B 1 228 ? 143.902 122.565 82.711  1.00 39.22  ? 248 ILE B CG2 1 
ATOM   7612  C CD1 . ILE B 1 228 ? 146.978 123.355 82.388  1.00 41.69  ? 248 ILE B CD1 1 
ATOM   7613  N N   . TYR B 1 229 ? 143.787 124.920 79.388  1.00 41.79  ? 249 TYR B N   1 
ATOM   7614  C CA  . TYR B 1 229 ? 143.588 124.503 78.013  1.00 43.36  ? 249 TYR B CA  1 
ATOM   7615  C C   . TYR B 1 229 ? 144.235 123.141 77.795  1.00 44.06  ? 249 TYR B C   1 
ATOM   7616  O O   . TYR B 1 229 ? 145.232 122.812 78.430  1.00 44.36  ? 249 TYR B O   1 
ATOM   7617  C CB  . TYR B 1 229 ? 144.146 125.546 77.045  1.00 45.22  ? 249 TYR B CB  1 
ATOM   7618  C CG  . TYR B 1 229 ? 143.192 126.671 76.740  1.00 47.46  ? 249 TYR B CG  1 
ATOM   7619  C CD1 . TYR B 1 229 ? 142.191 126.520 75.793  1.00 48.71  ? 249 TYR B CD1 1 
ATOM   7620  C CD2 . TYR B 1 229 ? 143.262 127.874 77.423  1.00 49.02  ? 249 TYR B CD2 1 
ATOM   7621  C CE1 . TYR B 1 229 ? 141.302 127.544 75.510  1.00 49.47  ? 249 TYR B CE1 1 
ATOM   7622  C CE2 . TYR B 1 229 ? 142.387 128.912 77.146  1.00 50.07  ? 249 TYR B CE2 1 
ATOM   7623  C CZ  . TYR B 1 229 ? 141.401 128.745 76.189  1.00 50.01  ? 249 TYR B CZ  1 
ATOM   7624  O OH  . TYR B 1 229 ? 140.520 129.765 75.919  1.00 49.90  ? 249 TYR B OH  1 
ATOM   7625  N N   . SER B 1 230 ? 143.652 122.365 76.880  1.00 46.03  ? 250 SER B N   1 
ATOM   7626  C CA  . SER B 1 230 ? 144.137 121.032 76.572  1.00 48.14  ? 250 SER B CA  1 
ATOM   7627  C C   . SER B 1 230 ? 145.542 121.101 75.977  1.00 50.60  ? 250 SER B C   1 
ATOM   7628  O O   . SER B 1 230 ? 146.387 120.262 76.282  1.00 50.52  ? 250 SER B O   1 
ATOM   7629  C CB  . SER B 1 230 ? 143.169 120.328 75.658  1.00 48.41  ? 250 SER B CB  1 
ATOM   7630  O OG  . SER B 1 230 ? 143.776 119.216 75.023  1.00 48.53  ? 250 SER B OG  1 
ATOM   7631  N N   . ASN B 1 231 ? 145.782 122.121 75.144  1.00 52.65  ? 251 ASN B N   1 
ATOM   7632  C CA  . ASN B 1 231 ? 147.032 122.258 74.412  1.00 54.11  ? 251 ASN B CA  1 
ATOM   7633  C C   . ASN B 1 231 ? 147.970 123.237 75.119  1.00 56.16  ? 251 ASN B C   1 
ATOM   7634  O O   . ASN B 1 231 ? 148.861 123.801 74.486  1.00 56.10  ? 251 ASN B O   1 
ATOM   7635  C CB  . ASN B 1 231 ? 146.767 122.696 72.969  1.00 54.34  ? 251 ASN B CB  1 
ATOM   7636  C CG  . ASN B 1 231 ? 145.985 123.989 72.882  1.00 54.85  ? 251 ASN B CG  1 
ATOM   7637  O OD1 . ASN B 1 231 ? 145.676 124.604 73.901  1.00 54.86  ? 251 ASN B OD1 1 
ATOM   7638  N ND2 . ASN B 1 231 ? 145.653 124.405 71.670  1.00 55.59  ? 251 ASN B ND2 1 
ATOM   7639  N N   . ALA B 1 232 ? 147.778 123.437 76.429  1.00 59.49  ? 252 ALA B N   1 
ATOM   7640  C CA  . ALA B 1 232 ? 148.654 124.305 77.201  1.00 62.29  ? 252 ALA B CA  1 
ATOM   7641  C C   . ALA B 1 232 ? 150.033 123.663 77.317  1.00 65.73  ? 252 ALA B C   1 
ATOM   7642  O O   . ALA B 1 232 ? 150.162 122.440 77.292  1.00 65.48  ? 252 ALA B O   1 
ATOM   7643  C CB  . ALA B 1 232 ? 148.064 124.578 78.564  1.00 62.03  ? 252 ALA B CB  1 
ATOM   7644  N N   . GLY B 1 233 ? 151.060 124.509 77.446  1.00 70.44  ? 253 GLY B N   1 
ATOM   7645  C CA  . GLY B 1 233 ? 152.435 124.049 77.536  1.00 74.52  ? 253 GLY B CA  1 
ATOM   7646  C C   . GLY B 1 233 ? 152.722 123.336 78.856  1.00 77.95  ? 253 GLY B C   1 
ATOM   7647  O O   . GLY B 1 233 ? 151.879 123.299 79.751  1.00 78.78  ? 253 GLY B O   1 
ATOM   7648  N N   . GLU B 1 234 ? 153.940 122.792 78.964  1.00 80.44  ? 254 GLU B N   1 
ATOM   7649  C CA  . GLU B 1 234 ? 154.352 122.036 80.135  1.00 83.13  ? 254 GLU B CA  1 
ATOM   7650  C C   . GLU B 1 234 ? 154.377 122.943 81.361  1.00 81.26  ? 254 GLU B C   1 
ATOM   7651  O O   . GLU B 1 234 ? 154.062 122.495 82.461  1.00 81.05  ? 254 GLU B O   1 
ATOM   7652  C CB  . GLU B 1 234 ? 155.720 121.390 79.911  1.00 87.59  ? 254 GLU B CB  1 
ATOM   7653  C CG  . GLU B 1 234 ? 155.669 120.216 78.955  1.00 93.00  ? 254 GLU B CG  1 
ATOM   7654  C CD  . GLU B 1 234 ? 155.396 120.620 77.517  1.00 98.73  ? 254 GLU B CD  1 
ATOM   7655  O OE1 . GLU B 1 234 ? 156.222 121.366 76.961  1.00 100.75 ? 254 GLU B OE1 1 
ATOM   7656  O OE2 . GLU B 1 234 ? 154.341 120.226 76.975  1.00 101.76 ? 254 GLU B OE2 1 
ATOM   7657  N N   . GLN B 1 235 ? 154.732 124.216 81.157  1.00 79.89  ? 255 GLN B N   1 
ATOM   7658  C CA  . GLN B 1 235 ? 154.864 125.166 82.250  1.00 80.09  ? 255 GLN B CA  1 
ATOM   7659  C C   . GLN B 1 235 ? 153.500 125.395 82.904  1.00 75.98  ? 255 GLN B C   1 
ATOM   7660  O O   . GLN B 1 235 ? 153.401 125.493 84.128  1.00 75.52  ? 255 GLN B O   1 
ATOM   7661  C CB  . GLN B 1 235 ? 155.455 126.493 81.766  1.00 83.88  ? 255 GLN B CB  1 
ATOM   7662  C CG  . GLN B 1 235 ? 156.761 126.363 80.993  1.00 87.32  ? 255 GLN B CG  1 
ATOM   7663  C CD  . GLN B 1 235 ? 156.547 126.044 79.532  1.00 90.66  ? 255 GLN B CD  1 
ATOM   7664  O OE1 . GLN B 1 235 ? 155.674 126.609 78.875  1.00 91.71  ? 255 GLN B OE1 1 
ATOM   7665  N NE2 . GLN B 1 235 ? 157.336 125.119 79.010  1.00 91.66  ? 255 GLN B NE2 1 
ATOM   7666  N N   . SER B 1 236 ? 152.453 125.483 82.072  1.00 70.87  ? 256 SER B N   1 
ATOM   7667  C CA  . SER B 1 236 ? 151.111 125.760 82.555  1.00 67.78  ? 256 SER B CA  1 
ATOM   7668  C C   . SER B 1 236 ? 150.623 124.607 83.429  1.00 64.41  ? 256 SER B C   1 
ATOM   7669  O O   . SER B 1 236 ? 150.050 124.836 84.491  1.00 64.74  ? 256 SER B O   1 
ATOM   7670  C CB  . SER B 1 236 ? 150.167 126.029 81.413  1.00 67.71  ? 256 SER B CB  1 
ATOM   7671  O OG  . SER B 1 236 ? 148.944 126.570 81.891  1.00 67.84  ? 256 SER B OG  1 
ATOM   7672  N N   . PHE B 1 237 ? 150.864 123.371 82.978  1.00 60.68  ? 257 PHE B N   1 
ATOM   7673  C CA  . PHE B 1 237 ? 150.487 122.188 83.736  1.00 58.86  ? 257 PHE B CA  1 
ATOM   7674  C C   . PHE B 1 237 ? 151.286 122.101 85.034  1.00 62.26  ? 257 PHE B C   1 
ATOM   7675  O O   . PHE B 1 237 ? 150.746 121.681 86.056  1.00 63.13  ? 257 PHE B O   1 
ATOM   7676  C CB  . PHE B 1 237 ? 150.662 120.933 82.882  1.00 56.45  ? 257 PHE B CB  1 
ATOM   7677  C CG  . PHE B 1 237 ? 149.490 120.656 81.978  1.00 54.61  ? 257 PHE B CG  1 
ATOM   7678  C CD1 . PHE B 1 237 ? 148.312 120.140 82.494  1.00 53.19  ? 257 PHE B CD1 1 
ATOM   7679  C CD2 . PHE B 1 237 ? 149.548 120.943 80.625  1.00 54.43  ? 257 PHE B CD2 1 
ATOM   7680  C CE1 . PHE B 1 237 ? 147.225 119.896 81.671  1.00 51.88  ? 257 PHE B CE1 1 
ATOM   7681  C CE2 . PHE B 1 237 ? 148.460 120.694 79.801  1.00 53.47  ? 257 PHE B CE2 1 
ATOM   7682  C CZ  . PHE B 1 237 ? 147.301 120.176 80.326  1.00 52.27  ? 257 PHE B CZ  1 
ATOM   7683  N N   . ASP B 1 238 ? 152.565 122.496 84.987  1.00 65.29  ? 258 ASP B N   1 
ATOM   7684  C CA  . ASP B 1 238 ? 153.404 122.505 86.173  1.00 66.56  ? 258 ASP B CA  1 
ATOM   7685  C C   . ASP B 1 238 ? 152.835 123.471 87.209  1.00 65.11  ? 258 ASP B C   1 
ATOM   7686  O O   . ASP B 1 238 ? 152.748 123.125 88.385  1.00 65.01  ? 258 ASP B O   1 
ATOM   7687  C CB  . ASP B 1 238 ? 154.856 122.843 85.830  1.00 69.31  ? 258 ASP B CB  1 
ATOM   7688  C CG  . ASP B 1 238 ? 155.616 121.669 85.240  1.00 71.94  ? 258 ASP B CG  1 
ATOM   7689  O OD1 . ASP B 1 238 ? 155.552 120.571 85.833  1.00 72.27  ? 258 ASP B OD1 1 
ATOM   7690  O OD2 . ASP B 1 238 ? 156.293 121.865 84.218  1.00 72.76  ? 258 ASP B OD2 1 
ATOM   7691  N N   . LYS B 1 239 ? 152.445 124.670 86.760  1.00 64.43  ? 259 LYS B N   1 
ATOM   7692  C CA  . LYS B 1 239 ? 151.889 125.676 87.651  1.00 65.14  ? 259 LYS B CA  1 
ATOM   7693  C C   . LYS B 1 239 ? 150.564 125.191 88.236  1.00 61.77  ? 259 LYS B C   1 
ATOM   7694  O O   . LYS B 1 239 ? 150.298 125.399 89.419  1.00 61.77  ? 259 LYS B O   1 
ATOM   7695  C CB  . LYS B 1 239 ? 151.723 127.010 86.918  1.00 68.41  ? 259 LYS B CB  1 
ATOM   7696  C CG  . LYS B 1 239 ? 153.012 127.802 86.744  1.00 71.32  ? 259 LYS B CG  1 
ATOM   7697  C CD  . LYS B 1 239 ? 152.801 129.180 86.146  1.00 73.52  ? 259 LYS B CD  1 
ATOM   7698  C CE  . LYS B 1 239 ? 152.560 129.171 84.650  1.00 74.25  ? 259 LYS B CE  1 
ATOM   7699  N NZ  . LYS B 1 239 ? 153.798 128.868 83.892  1.00 74.14  ? 259 LYS B NZ  1 
ATOM   7700  N N   . LEU B 1 240 ? 149.738 124.550 87.400  1.00 59.05  ? 260 LEU B N   1 
ATOM   7701  C CA  . LEU B 1 240 ? 148.456 124.029 87.848  1.00 57.61  ? 260 LEU B CA  1 
ATOM   7702  C C   . LEU B 1 240 ? 148.674 122.984 88.938  1.00 58.33  ? 260 LEU B C   1 
ATOM   7703  O O   . LEU B 1 240 ? 147.951 122.972 89.934  1.00 60.13  ? 260 LEU B O   1 
ATOM   7704  C CB  . LEU B 1 240 ? 147.691 123.438 86.658  1.00 55.94  ? 260 LEU B CB  1 
ATOM   7705  C CG  . LEU B 1 240 ? 146.557 122.473 87.007  1.00 54.03  ? 260 LEU B CG  1 
ATOM   7706  C CD1 . LEU B 1 240 ? 145.455 123.169 87.778  1.00 53.90  ? 260 LEU B CD1 1 
ATOM   7707  C CD2 . LEU B 1 240 ? 145.985 121.836 85.753  1.00 53.37  ? 260 LEU B CD2 1 
ATOM   7708  N N   . LEU B 1 241 ? 149.667 122.108 88.744  1.00 57.98  ? 261 LEU B N   1 
ATOM   7709  C CA  . LEU B 1 241 ? 149.893 121.037 89.697  1.00 58.09  ? 261 LEU B CA  1 
ATOM   7710  C C   . LEU B 1 241 ? 150.476 121.597 90.993  1.00 61.02  ? 261 LEU B C   1 
ATOM   7711  O O   . LEU B 1 241 ? 150.175 121.072 92.064  1.00 62.50  ? 261 LEU B O   1 
ATOM   7712  C CB  . LEU B 1 241 ? 150.810 119.972 89.091  1.00 56.70  ? 261 LEU B CB  1 
ATOM   7713  C CG  . LEU B 1 241 ? 150.871 118.668 89.884  1.00 55.94  ? 261 LEU B CG  1 
ATOM   7714  C CD1 . LEU B 1 241 ? 149.555 117.915 89.789  1.00 55.89  ? 261 LEU B CD1 1 
ATOM   7715  C CD2 . LEU B 1 241 ? 152.017 117.794 89.411  1.00 55.97  ? 261 LEU B CD2 1 
ATOM   7716  N N   . LYS B 1 242 ? 151.294 122.654 90.898  1.00 62.63  ? 262 LYS B N   1 
ATOM   7717  C CA  . LYS B 1 242 ? 151.823 123.317 92.083  1.00 63.93  ? 262 LYS B CA  1 
ATOM   7718  C C   . LYS B 1 242 ? 150.668 123.888 92.903  1.00 62.36  ? 262 LYS B C   1 
ATOM   7719  O O   . LYS B 1 242 ? 150.647 123.752 94.125  1.00 62.60  ? 262 LYS B O   1 
ATOM   7720  C CB  . LYS B 1 242 ? 152.807 124.431 91.705  1.00 67.17  ? 262 LYS B CB  1 
ATOM   7721  C CG  . LYS B 1 242 ? 154.104 123.979 91.046  1.00 70.82  ? 262 LYS B CG  1 
ATOM   7722  C CD  . LYS B 1 242 ? 155.277 123.817 91.995  1.00 73.78  ? 262 LYS B CD  1 
ATOM   7723  C CE  . LYS B 1 242 ? 156.445 123.075 91.376  1.00 75.66  ? 262 LYS B CE  1 
ATOM   7724  N NZ  . LYS B 1 242 ? 156.901 123.691 90.106  1.00 75.72  ? 262 LYS B NZ  1 
ATOM   7725  N N   . LYS B 1 243 ? 149.705 124.523 92.221  1.00 61.13  ? 263 LYS B N   1 
ATOM   7726  C CA  . LYS B 1 243 ? 148.543 125.078 92.893  1.00 60.87  ? 263 LYS B CA  1 
ATOM   7727  C C   . LYS B 1 243 ? 147.702 123.961 93.504  1.00 60.12  ? 263 LYS B C   1 
ATOM   7728  O O   . LYS B 1 243 ? 147.149 124.144 94.583  1.00 61.09  ? 263 LYS B O   1 
ATOM   7729  C CB  . LYS B 1 243 ? 147.720 125.937 91.931  1.00 62.42  ? 263 LYS B CB  1 
ATOM   7730  C CG  . LYS B 1 243 ? 148.350 127.281 91.593  1.00 64.16  ? 263 LYS B CG  1 
ATOM   7731  C CD  . LYS B 1 243 ? 147.400 128.236 90.905  1.00 66.10  ? 263 LYS B CD  1 
ATOM   7732  C CE  . LYS B 1 243 ? 147.167 127.904 89.447  1.00 66.88  ? 263 LYS B CE  1 
ATOM   7733  N NZ  . LYS B 1 243 ? 148.343 128.256 88.618  1.00 67.79  ? 263 LYS B NZ  1 
ATOM   7734  N N   . LEU B 1 244 ? 147.614 122.810 92.827  1.00 60.40  ? 264 LEU B N   1 
ATOM   7735  C CA  . LEU B 1 244 ? 146.885 121.671 93.366  1.00 61.61  ? 264 LEU B CA  1 
ATOM   7736  C C   . LEU B 1 244 ? 147.545 121.180 94.652  1.00 64.17  ? 264 LEU B C   1 
ATOM   7737  O O   . LEU B 1 244 ? 146.849 120.848 95.610  1.00 64.93  ? 264 LEU B O   1 
ATOM   7738  C CB  . LEU B 1 244 ? 146.814 120.549 92.323  1.00 59.76  ? 264 LEU B CB  1 
ATOM   7739  C CG  . LEU B 1 244 ? 145.695 120.663 91.288  1.00 58.00  ? 264 LEU B CG  1 
ATOM   7740  C CD1 . LEU B 1 244 ? 145.732 119.478 90.337  1.00 57.05  ? 264 LEU B CD1 1 
ATOM   7741  C CD2 . LEU B 1 244 ? 144.325 120.758 91.953  1.00 57.37  ? 264 LEU B CD2 1 
ATOM   7742  N N   . THR B 1 245 ? 148.884 121.157 94.672  1.00 66.11  ? 265 THR B N   1 
ATOM   7743  C CA  . THR B 1 245 ? 149.624 120.685 95.832  1.00 68.10  ? 265 THR B CA  1 
ATOM   7744  C C   . THR B 1 245 ? 149.607 121.716 96.963  1.00 70.40  ? 265 THR B C   1 
ATOM   7745  O O   . THR B 1 245 ? 149.892 121.371 98.106  1.00 70.65  ? 265 THR B O   1 
ATOM   7746  C CB  . THR B 1 245 ? 151.065 120.316 95.462  1.00 68.40  ? 265 THR B CB  1 
ATOM   7747  O OG1 . THR B 1 245 ? 151.697 121.484 94.935  1.00 68.93  ? 265 THR B OG1 1 
ATOM   7748  C CG2 . THR B 1 245 ? 151.133 119.172 94.472  1.00 68.41  ? 265 THR B CG2 1 
ATOM   7749  N N   . SER B 1 246 ? 149.276 122.975 96.653  1.00 73.02  ? 266 SER B N   1 
ATOM   7750  C CA  . SER B 1 246 ? 149.182 124.010 97.675  1.00 76.07  ? 266 SER B CA  1 
ATOM   7751  C C   . SER B 1 246 ? 148.098 123.683 98.704  1.00 78.90  ? 266 SER B C   1 
ATOM   7752  O O   . SER B 1 246 ? 148.110 124.240 99.799  1.00 79.73  ? 266 SER B O   1 
ATOM   7753  C CB  . SER B 1 246 ? 148.947 125.366 97.062  1.00 77.47  ? 266 SER B CB  1 
ATOM   7754  O OG  . SER B 1 246 ? 148.827 126.359 98.070  1.00 78.63  ? 266 SER B OG  1 
ATOM   7755  N N   . HIS B 1 247 ? 147.164 122.792 98.351  1.00 82.51  ? 267 HIS B N   1 
ATOM   7756  C CA  . HIS B 1 247 ? 146.132 122.340 99.269  1.00 87.63  ? 267 HIS B CA  1 
ATOM   7757  C C   . HIS B 1 247 ? 146.222 120.828 99.458  1.00 88.25  ? 267 HIS B C   1 
ATOM   7758  O O   . HIS B 1 247 ? 145.197 120.170 99.602  1.00 87.02  ? 267 HIS B O   1 
ATOM   7759  C CB  . HIS B 1 247 ? 144.741 122.668 98.713  1.00 92.54  ? 267 HIS B CB  1 
ATOM   7760  C CG  . HIS B 1 247 ? 144.494 124.116 98.463  1.00 97.42  ? 267 HIS B CG  1 
ATOM   7761  N ND1 . HIS B 1 247 ? 144.621 124.680 97.212  1.00 99.43  ? 267 HIS B ND1 1 
ATOM   7762  C CD2 . HIS B 1 247 ? 144.114 125.113 99.281  1.00 99.84  ? 267 HIS B CD2 1 
ATOM   7763  C CE1 . HIS B 1 247 ? 144.333 125.973 97.283  1.00 101.34 ? 267 HIS B CE1 1 
ATOM   7764  N NE2 . HIS B 1 247 ? 144.022 126.256 98.529  1.00 101.13 ? 267 HIS B NE2 1 
ATOM   7765  N N   . LEU B 1 248 ? 147.444 120.279 99.500  1.00 89.01  ? 268 LEU B N   1 
ATOM   7766  C CA  . LEU B 1 248 ? 147.634 118.849 99.301  1.00 89.47  ? 268 LEU B CA  1 
ATOM   7767  C C   . LEU B 1 248 ? 147.140 118.047 100.506 1.00 90.34  ? 268 LEU B C   1 
ATOM   7768  O O   . LEU B 1 248 ? 146.319 117.150 100.335 1.00 90.92  ? 268 LEU B O   1 
ATOM   7769  C CB  . LEU B 1 248 ? 149.110 118.563 99.005  1.00 88.93  ? 268 LEU B CB  1 
ATOM   7770  C CG  . LEU B 1 248 ? 149.388 117.380 98.080  1.00 88.94  ? 268 LEU B CG  1 
ATOM   7771  C CD1 . LEU B 1 248 ? 150.868 117.333 97.738  1.00 90.87  ? 268 LEU B CD1 1 
ATOM   7772  C CD2 . LEU B 1 248 ? 148.932 116.070 98.704  1.00 88.42  ? 268 LEU B CD2 1 
ATOM   7773  N N   . PRO B 1 249 ? 147.602 118.310 101.753 1.00 89.88  ? 269 PRO B N   1 
ATOM   7774  C CA  . PRO B 1 249 ? 147.295 117.417 102.873 1.00 89.99  ? 269 PRO B CA  1 
ATOM   7775  C C   . PRO B 1 249 ? 145.798 117.219 103.113 1.00 90.62  ? 269 PRO B C   1 
ATOM   7776  O O   . PRO B 1 249 ? 145.378 116.153 103.558 1.00 91.06  ? 269 PRO B O   1 
ATOM   7777  C CB  . PRO B 1 249 ? 147.947 118.101 104.086 1.00 90.45  ? 269 PRO B CB  1 
ATOM   7778  C CG  . PRO B 1 249 ? 149.002 119.007 103.483 1.00 90.80  ? 269 PRO B CG  1 
ATOM   7779  C CD  . PRO B 1 249 ? 148.409 119.468 102.169 1.00 89.80  ? 269 PRO B CD  1 
ATOM   7780  N N   . LYS B 1 250 ? 145.001 118.247 102.793 1.00 90.59  ? 270 LYS B N   1 
ATOM   7781  C CA  . LYS B 1 250 ? 143.594 118.287 103.152 1.00 91.31  ? 270 LYS B CA  1 
ATOM   7782  C C   . LYS B 1 250 ? 142.717 117.960 101.943 1.00 86.93  ? 270 LYS B C   1 
ATOM   7783  O O   . LYS B 1 250 ? 141.669 117.339 102.110 1.00 86.57  ? 270 LYS B O   1 
ATOM   7784  C CB  . LYS B 1 250 ? 143.259 119.662 103.740 1.00 95.43  ? 270 LYS B CB  1 
ATOM   7785  C CG  . LYS B 1 250 ? 144.319 120.232 104.674 1.00 98.76  ? 270 LYS B CG  1 
ATOM   7786  C CD  . LYS B 1 250 ? 143.859 121.418 105.491 1.00 102.41 ? 270 LYS B CD  1 
ATOM   7787  C CE  . LYS B 1 250 ? 142.977 121.019 106.654 1.00 104.19 ? 270 LYS B CE  1 
ATOM   7788  N NZ  . LYS B 1 250 ? 142.563 122.191 107.462 1.00 104.67 ? 270 LYS B NZ  1 
ATOM   7789  N N   . ALA B 1 251 ? 143.108 118.432 100.749 1.00 80.89  ? 271 ALA B N   1 
ATOM   7790  C CA  . ALA B 1 251 ? 142.382 118.156 99.516  1.00 74.91  ? 271 ALA B CA  1 
ATOM   7791  C C   . ALA B 1 251 ? 143.175 117.157 98.678  1.00 68.48  ? 271 ALA B C   1 
ATOM   7792  O O   . ALA B 1 251 ? 144.047 117.546 97.904  1.00 67.34  ? 271 ALA B O   1 
ATOM   7793  C CB  . ALA B 1 251 ? 142.129 119.441 98.747  1.00 74.45  ? 271 ALA B CB  1 
ATOM   7794  N N   . ARG B 1 252 ? 142.854 115.868 98.834  1.00 62.77  ? 272 ARG B N   1 
ATOM   7795  C CA  . ARG B 1 252 ? 143.595 114.802 98.180  1.00 59.37  ? 272 ARG B CA  1 
ATOM   7796  C C   . ARG B 1 252 ? 142.841 114.294 96.952  1.00 55.09  ? 272 ARG B C   1 
ATOM   7797  O O   . ARG B 1 252 ? 143.402 113.547 96.157  1.00 55.88  ? 272 ARG B O   1 
ATOM   7798  C CB  . ARG B 1 252 ? 143.860 113.673 99.181  1.00 61.39  ? 272 ARG B CB  1 
ATOM   7799  C CG  . ARG B 1 252 ? 144.900 112.659 98.723  1.00 63.14  ? 272 ARG B CG  1 
ATOM   7800  C CD  . ARG B 1 252 ? 145.444 111.837 99.877  1.00 64.74  ? 272 ARG B CD  1 
ATOM   7801  N NE  . ARG B 1 252 ? 146.295 112.625 100.762 1.00 66.54  ? 272 ARG B NE  1 
ATOM   7802  C CZ  . ARG B 1 252 ? 147.564 112.956 100.517 1.00 68.63  ? 272 ARG B CZ  1 
ATOM   7803  N NH1 . ARG B 1 252 ? 148.181 112.508 99.438  1.00 69.24  ? 272 ARG B NH1 1 
ATOM   7804  N NH2 . ARG B 1 252 ? 148.223 113.726 101.367 1.00 69.03  ? 272 ARG B NH2 1 
ATOM   7805  N N   . VAL B 1 253 ? 141.570 114.686 96.804  1.00 51.01  ? 273 VAL B N   1 
ATOM   7806  C CA  . VAL B 1 253 ? 140.761 114.266 95.671  1.00 47.57  ? 273 VAL B CA  1 
ATOM   7807  C C   . VAL B 1 253 ? 140.591 115.446 94.720  1.00 45.18  ? 273 VAL B C   1 
ATOM   7808  O O   . VAL B 1 253 ? 140.153 116.521 95.119  1.00 44.78  ? 273 VAL B O   1 
ATOM   7809  C CB  . VAL B 1 253 ? 139.399 113.714 96.126  1.00 47.46  ? 273 VAL B CB  1 
ATOM   7810  C CG1 . VAL B 1 253 ? 138.445 113.495 94.962  1.00 47.58  ? 273 VAL B CG1 1 
ATOM   7811  C CG2 . VAL B 1 253 ? 139.564 112.435 96.930  1.00 48.00  ? 273 VAL B CG2 1 
ATOM   7812  N N   . VAL B 1 254 ? 140.947 115.218 93.454  1.00 43.03  ? 274 VAL B N   1 
ATOM   7813  C CA  . VAL B 1 254 ? 140.790 116.220 92.415  1.00 40.84  ? 274 VAL B CA  1 
ATOM   7814  C C   . VAL B 1 254 ? 139.696 115.745 91.467  1.00 40.15  ? 274 VAL B C   1 
ATOM   7815  O O   . VAL B 1 254 ? 139.898 114.789 90.723  1.00 41.01  ? 274 VAL B O   1 
ATOM   7816  C CB  . VAL B 1 254 ? 142.099 116.479 91.647  1.00 39.99  ? 274 VAL B CB  1 
ATOM   7817  C CG1 . VAL B 1 254 ? 141.922 117.623 90.667  1.00 39.72  ? 274 VAL B CG1 1 
ATOM   7818  C CG2 . VAL B 1 254 ? 143.280 116.739 92.568  1.00 40.65  ? 274 VAL B CG2 1 
ATOM   7819  N N   . ALA B 1 255 ? 138.533 116.404 91.519  1.00 38.69  ? 275 ALA B N   1 
ATOM   7820  C CA  . ALA B 1 255 ? 137.467 116.153 90.563  1.00 37.71  ? 275 ALA B CA  1 
ATOM   7821  C C   . ALA B 1 255 ? 137.850 116.778 89.226  1.00 36.69  ? 275 ALA B C   1 
ATOM   7822  O O   . ALA B 1 255 ? 137.977 117.994 89.122  1.00 37.26  ? 275 ALA B O   1 
ATOM   7823  C CB  . ALA B 1 255 ? 136.160 116.707 91.075  1.00 37.93  ? 275 ALA B CB  1 
ATOM   7824  N N   . CYS B 1 256 ? 138.070 115.929 88.219  1.00 35.45  ? 276 CYS B N   1 
ATOM   7825  C CA  . CYS B 1 256 ? 138.502 116.388 86.915  1.00 34.66  ? 276 CYS B CA  1 
ATOM   7826  C C   . CYS B 1 256 ? 137.348 116.247 85.929  1.00 33.92  ? 276 CYS B C   1 
ATOM   7827  O O   . CYS B 1 256 ? 136.985 115.143 85.539  1.00 34.56  ? 276 CYS B O   1 
ATOM   7828  C CB  . CYS B 1 256 ? 139.745 115.626 86.469  1.00 35.48  ? 276 CYS B CB  1 
ATOM   7829  S SG  . CYS B 1 256 ? 140.374 115.988 84.806  1.00 37.54  ? 276 CYS B SG  1 
ATOM   7830  N N   . PHE B 1 257 ? 136.796 117.388 85.517  1.00 33.06  ? 277 PHE B N   1 
ATOM   7831  C CA  . PHE B 1 257 ? 135.895 117.444 84.379  1.00 32.80  ? 277 PHE B CA  1 
ATOM   7832  C C   . PHE B 1 257 ? 136.702 117.771 83.132  1.00 32.03  ? 277 PHE B C   1 
ATOM   7833  O O   . PHE B 1 257 ? 136.384 118.719 82.412  1.00 32.32  ? 277 PHE B O   1 
ATOM   7834  C CB  . PHE B 1 257 ? 134.779 118.461 84.623  1.00 33.41  ? 277 PHE B CB  1 
ATOM   7835  C CG  . PHE B 1 257 ? 133.413 117.845 84.735  1.00 34.50  ? 277 PHE B CG  1 
ATOM   7836  C CD1 . PHE B 1 257 ? 132.692 117.512 83.601  1.00 34.98  ? 277 PHE B CD1 1 
ATOM   7837  C CD2 . PHE B 1 257 ? 132.860 117.581 85.974  1.00 35.43  ? 277 PHE B CD2 1 
ATOM   7838  C CE1 . PHE B 1 257 ? 131.437 116.930 83.707  1.00 35.64  ? 277 PHE B CE1 1 
ATOM   7839  C CE2 . PHE B 1 257 ? 131.617 116.978 86.080  1.00 36.17  ? 277 PHE B CE2 1 
ATOM   7840  C CZ  . PHE B 1 257 ? 130.898 116.673 84.946  1.00 36.36  ? 277 PHE B CZ  1 
ATOM   7841  N N   . CYS B 1 258 ? 137.740 116.967 82.881  1.00 31.45  ? 278 CYS B N   1 
ATOM   7842  C CA  . CYS B 1 258 ? 138.724 117.317 81.875  1.00 31.26  ? 278 CYS B CA  1 
ATOM   7843  C C   . CYS B 1 258 ? 138.667 116.344 80.702  1.00 30.75  ? 278 CYS B C   1 
ATOM   7844  O O   . CYS B 1 258 ? 138.052 115.285 80.797  1.00 31.30  ? 278 CYS B O   1 
ATOM   7845  C CB  . CYS B 1 258 ? 140.125 117.327 82.458  1.00 32.28  ? 278 CYS B CB  1 
ATOM   7846  S SG  . CYS B 1 258 ? 140.225 117.926 84.163  1.00 34.52  ? 278 CYS B SG  1 
ATOM   7847  N N   . GLU B 1 259 ? 139.328 116.727 79.607  1.00 30.27  ? 279 GLU B N   1 
ATOM   7848  C CA  . GLU B 1 259 ? 139.477 115.865 78.449  1.00 30.24  ? 279 GLU B CA  1 
ATOM   7849  C C   . GLU B 1 259 ? 140.620 114.887 78.705  1.00 29.48  ? 279 GLU B C   1 
ATOM   7850  O O   . GLU B 1 259 ? 141.240 114.914 79.764  1.00 29.58  ? 279 GLU B O   1 
ATOM   7851  C CB  . GLU B 1 259 ? 139.749 116.715 77.208  1.00 31.38  ? 279 GLU B CB  1 
ATOM   7852  C CG  . GLU B 1 259 ? 138.657 117.724 76.923  1.00 32.65  ? 279 GLU B CG  1 
ATOM   7853  C CD  . GLU B 1 259 ? 138.864 118.470 75.618  1.00 34.05  ? 279 GLU B CD  1 
ATOM   7854  O OE1 . GLU B 1 259 ? 140.007 118.916 75.383  1.00 34.53  ? 279 GLU B OE1 1 
ATOM   7855  O OE2 . GLU B 1 259 ? 137.887 118.607 74.841  1.00 34.71  ? 279 GLU B OE2 1 
ATOM   7856  N N   . GLY B 1 260 ? 140.890 114.023 77.726  1.00 29.76  ? 280 GLY B N   1 
ATOM   7857  C CA  . GLY B 1 260 ? 141.995 113.091 77.833  1.00 30.31  ? 280 GLY B CA  1 
ATOM   7858  C C   . GLY B 1 260 ? 143.343 113.800 77.923  1.00 30.85  ? 280 GLY B C   1 
ATOM   7859  O O   . GLY B 1 260 ? 144.193 113.403 78.713  1.00 31.64  ? 280 GLY B O   1 
ATOM   7860  N N   . MET B 1 261 ? 143.533 114.848 77.116  1.00 31.22  ? 281 MET B N   1 
ATOM   7861  C CA  . MET B 1 261 ? 144.827 115.501 77.030  1.00 31.95  ? 281 MET B CA  1 
ATOM   7862  C C   . MET B 1 261 ? 145.097 116.340 78.276  1.00 30.44  ? 281 MET B C   1 
ATOM   7863  O O   . MET B 1 261 ? 146.249 116.474 78.678  1.00 30.83  ? 281 MET B O   1 
ATOM   7864  C CB  . MET B 1 261 ? 144.928 116.375 75.777  1.00 34.22  ? 281 MET B CB  1 
ATOM   7865  C CG  . MET B 1 261 ? 145.179 115.570 74.512  1.00 36.43  ? 281 MET B CG  1 
ATOM   7866  S SD  . MET B 1 261 ? 146.359 114.205 74.750  1.00 39.35  ? 281 MET B SD  1 
ATOM   7867  C CE  . MET B 1 261 ? 145.236 112.812 74.893  1.00 39.18  ? 281 MET B CE  1 
ATOM   7868  N N   . THR B 1 262 ? 144.049 116.892 78.893  1.00 28.87  ? 282 THR B N   1 
ATOM   7869  C CA  . THR B 1 262 ? 144.236 117.629 80.130  1.00 28.00  ? 282 THR B CA  1 
ATOM   7870  C C   . THR B 1 262 ? 144.701 116.680 81.231  1.00 27.74  ? 282 THR B C   1 
ATOM   7871  O O   . THR B 1 262 ? 145.610 117.004 81.989  1.00 28.52  ? 282 THR B O   1 
ATOM   7872  C CB  . THR B 1 262 ? 142.964 118.363 80.555  1.00 27.75  ? 282 THR B CB  1 
ATOM   7873  O OG1 . THR B 1 262 ? 142.589 119.239 79.495  1.00 27.49  ? 282 THR B OG1 1 
ATOM   7874  C CG2 . THR B 1 262 ? 143.137 119.137 81.846  1.00 27.95  ? 282 THR B CG2 1 
ATOM   7875  N N   . VAL B 1 263 ? 144.064 115.512 81.321  1.00 27.24  ? 283 VAL B N   1 
ATOM   7876  C CA  . VAL B 1 263 ? 144.443 114.527 82.319  1.00 26.84  ? 283 VAL B CA  1 
ATOM   7877  C C   . VAL B 1 263 ? 145.872 114.067 82.047  1.00 27.48  ? 283 VAL B C   1 
ATOM   7878  O O   . VAL B 1 263 ? 146.654 113.912 82.978  1.00 28.45  ? 283 VAL B O   1 
ATOM   7879  C CB  . VAL B 1 263 ? 143.463 113.341 82.352  1.00 26.45  ? 283 VAL B CB  1 
ATOM   7880  C CG1 . VAL B 1 263 ? 144.034 112.163 83.124  1.00 26.65  ? 283 VAL B CG1 1 
ATOM   7881  C CG2 . VAL B 1 263 ? 142.111 113.750 82.915  1.00 26.33  ? 283 VAL B CG2 1 
ATOM   7882  N N   . ARG B 1 264 ? 146.207 113.843 80.773  1.00 28.05  ? 284 ARG B N   1 
ATOM   7883  C CA  . ARG B 1 264 ? 147.537 113.374 80.421  1.00 28.70  ? 284 ARG B CA  1 
ATOM   7884  C C   . ARG B 1 264 ? 148.570 114.438 80.778  1.00 29.18  ? 284 ARG B C   1 
ATOM   7885  O O   . ARG B 1 264 ? 149.654 114.104 81.241  1.00 30.03  ? 284 ARG B O   1 
ATOM   7886  C CB  . ARG B 1 264 ? 147.631 112.999 78.940  1.00 29.42  ? 284 ARG B CB  1 
ATOM   7887  C CG  . ARG B 1 264 ? 148.961 112.362 78.564  1.00 30.37  ? 284 ARG B CG  1 
ATOM   7888  C CD  . ARG B 1 264 ? 148.879 111.604 77.253  1.00 31.50  ? 284 ARG B CD  1 
ATOM   7889  N NE  . ARG B 1 264 ? 150.155 111.024 76.852  1.00 32.61  ? 284 ARG B NE  1 
ATOM   7890  C CZ  . ARG B 1 264 ? 150.729 109.954 77.402  1.00 33.87  ? 284 ARG B CZ  1 
ATOM   7891  N NH1 . ARG B 1 264 ? 150.118 109.264 78.350  1.00 33.98  ? 284 ARG B NH1 1 
ATOM   7892  N NH2 . ARG B 1 264 ? 151.922 109.563 76.984  1.00 34.42  ? 284 ARG B NH2 1 
ATOM   7893  N N   . GLY B 1 265 ? 148.227 115.713 80.572  1.00 29.48  ? 285 GLY B N   1 
ATOM   7894  C CA  . GLY B 1 265 ? 149.095 116.817 80.951  1.00 29.86  ? 285 GLY B CA  1 
ATOM   7895  C C   . GLY B 1 265 ? 149.358 116.849 82.455  1.00 29.91  ? 285 GLY B C   1 
ATOM   7896  O O   . GLY B 1 265 ? 150.486 117.071 82.890  1.00 30.52  ? 285 GLY B O   1 
ATOM   7897  N N   . LEU B 1 266 ? 148.306 116.613 83.245  1.00 30.04  ? 286 LEU B N   1 
ATOM   7898  C CA  . LEU B 1 266 ? 148.444 116.525 84.689  1.00 30.43  ? 286 LEU B CA  1 
ATOM   7899  C C   . LEU B 1 266 ? 149.335 115.348 85.079  1.00 31.09  ? 286 LEU B C   1 
ATOM   7900  O O   . LEU B 1 266 ? 150.132 115.473 86.000  1.00 32.17  ? 286 LEU B O   1 
ATOM   7901  C CB  . LEU B 1 266 ? 147.058 116.408 85.329  1.00 30.41  ? 286 LEU B CB  1 
ATOM   7902  C CG  . LEU B 1 266 ? 146.404 117.734 85.697  1.00 30.19  ? 286 LEU B CG  1 
ATOM   7903  C CD1 . LEU B 1 266 ? 145.000 117.518 86.239  1.00 30.27  ? 286 LEU B CD1 1 
ATOM   7904  C CD2 . LEU B 1 266 ? 147.257 118.472 86.713  1.00 30.36  ? 286 LEU B CD2 1 
ATOM   7905  N N   . LEU B 1 267 ? 149.211 114.218 84.376  1.00 31.88  ? 287 LEU B N   1 
ATOM   7906  C CA  . LEU B 1 267 ? 150.027 113.052 84.674  1.00 33.29  ? 287 LEU B CA  1 
ATOM   7907  C C   . LEU B 1 267 ? 151.493 113.326 84.351  1.00 35.84  ? 287 LEU B C   1 
ATOM   7908  O O   . LEU B 1 267 ? 152.368 112.931 85.115  1.00 36.91  ? 287 LEU B O   1 
ATOM   7909  C CB  . LEU B 1 267 ? 149.511 111.848 83.882  1.00 32.89  ? 287 LEU B CB  1 
ATOM   7910  C CG  . LEU B 1 267 ? 148.099 111.384 84.229  1.00 32.35  ? 287 LEU B CG  1 
ATOM   7911  C CD1 . LEU B 1 267 ? 147.828 110.027 83.607  1.00 32.24  ? 287 LEU B CD1 1 
ATOM   7912  C CD2 . LEU B 1 267 ? 147.883 111.341 85.735  1.00 32.40  ? 287 LEU B CD2 1 
ATOM   7913  N N   . MET B 1 268 ? 151.757 114.017 83.240  1.00 38.82  ? 288 MET B N   1 
ATOM   7914  C CA  . MET B 1 268 ? 153.122 114.354 82.872  1.00 41.81  ? 288 MET B CA  1 
ATOM   7915  C C   . MET B 1 268 ? 153.715 115.314 83.902  1.00 41.48  ? 288 MET B C   1 
ATOM   7916  O O   . MET B 1 268 ? 154.888 115.199 84.259  1.00 42.08  ? 288 MET B O   1 
ATOM   7917  C CB  . MET B 1 268 ? 153.182 114.975 81.473  1.00 44.83  ? 288 MET B CB  1 
ATOM   7918  C CG  . MET B 1 268 ? 152.538 114.104 80.406  1.00 47.01  ? 288 MET B CG  1 
ATOM   7919  S SD  . MET B 1 268 ? 153.297 114.241 78.766  1.00 51.19  ? 288 MET B SD  1 
ATOM   7920  C CE  . MET B 1 268 ? 153.457 116.020 78.595  1.00 51.85  ? 288 MET B CE  1 
ATOM   7921  N N   . ALA B 1 269 ? 152.892 116.249 84.390  1.00 41.70  ? 289 ALA B N   1 
ATOM   7922  C CA  . ALA B 1 269 ? 153.337 117.175 85.416  1.00 42.92  ? 289 ALA B CA  1 
ATOM   7923  C C   . ALA B 1 269 ? 153.686 116.408 86.691  1.00 43.67  ? 289 ALA B C   1 
ATOM   7924  O O   . ALA B 1 269 ? 154.679 116.716 87.343  1.00 45.57  ? 289 ALA B O   1 
ATOM   7925  C CB  . ALA B 1 269 ? 152.288 118.229 85.668  1.00 43.46  ? 289 ALA B CB  1 
ATOM   7926  N N   . MET B 1 270 ? 152.868 115.410 87.044  1.00 44.25  ? 290 MET B N   1 
ATOM   7927  C CA  . MET B 1 270 ? 153.115 114.618 88.238  1.00 45.53  ? 290 MET B CA  1 
ATOM   7928  C C   . MET B 1 270 ? 154.432 113.865 88.079  1.00 48.14  ? 290 MET B C   1 
ATOM   7929  O O   . MET B 1 270 ? 155.169 113.706 89.043  1.00 50.19  ? 290 MET B O   1 
ATOM   7930  C CB  . MET B 1 270 ? 151.976 113.629 88.497  1.00 45.31  ? 290 MET B CB  1 
ATOM   7931  C CG  . MET B 1 270 ? 150.713 114.308 88.974  1.00 45.43  ? 290 MET B CG  1 
ATOM   7932  S SD  . MET B 1 270 ? 149.312 113.180 89.084  1.00 46.43  ? 290 MET B SD  1 
ATOM   7933  C CE  . MET B 1 270 ? 149.350 112.823 90.839  1.00 47.26  ? 290 MET B CE  1 
ATOM   7934  N N   . ARG B 1 271 ? 154.736 113.415 86.859  1.00 51.31  ? 291 ARG B N   1 
ATOM   7935  C CA  . ARG B 1 271 ? 155.993 112.730 86.605  1.00 54.79  ? 291 ARG B CA  1 
ATOM   7936  C C   . ARG B 1 271 ? 157.161 113.690 86.808  1.00 56.80  ? 291 ARG B C   1 
ATOM   7937  O O   . ARG B 1 271 ? 158.162 113.317 87.414  1.00 57.72  ? 291 ARG B O   1 
ATOM   7938  C CB  . ARG B 1 271 ? 156.024 112.161 85.186  1.00 57.38  ? 291 ARG B CB  1 
ATOM   7939  C CG  . ARG B 1 271 ? 157.371 111.593 84.760  1.00 58.98  ? 291 ARG B CG  1 
ATOM   7940  C CD  . ARG B 1 271 ? 157.816 110.415 85.607  1.00 60.22  ? 291 ARG B CD  1 
ATOM   7941  N NE  . ARG B 1 271 ? 156.895 109.285 85.555  1.00 61.10  ? 291 ARG B NE  1 
ATOM   7942  C CZ  . ARG B 1 271 ? 156.635 108.552 84.474  1.00 62.49  ? 291 ARG B CZ  1 
ATOM   7943  N NH1 . ARG B 1 271 ? 157.274 108.768 83.336  1.00 62.30  ? 291 ARG B NH1 1 
ATOM   7944  N NH2 . ARG B 1 271 ? 155.745 107.578 84.543  1.00 63.21  ? 291 ARG B NH2 1 
ATOM   7945  N N   . ARG B 1 272 ? 157.025 114.916 86.292  1.00 60.51  ? 292 ARG B N   1 
ATOM   7946  C CA  . ARG B 1 272 ? 158.131 115.862 86.267  1.00 64.38  ? 292 ARG B CA  1 
ATOM   7947  C C   . ARG B 1 272 ? 158.545 116.254 87.685  1.00 65.97  ? 292 ARG B C   1 
ATOM   7948  O O   . ARG B 1 272 ? 159.741 116.302 87.974  1.00 66.86  ? 292 ARG B O   1 
ATOM   7949  C CB  . ARG B 1 272 ? 157.777 117.105 85.442  1.00 65.90  ? 292 ARG B CB  1 
ATOM   7950  C CG  . ARG B 1 272 ? 157.962 116.924 83.942  1.00 67.63  ? 292 ARG B CG  1 
ATOM   7951  C CD  . ARG B 1 272 ? 157.974 118.258 83.224  1.00 69.76  ? 292 ARG B CD  1 
ATOM   7952  N NE  . ARG B 1 272 ? 156.664 118.895 83.234  1.00 71.33  ? 292 ARG B NE  1 
ATOM   7953  C CZ  . ARG B 1 272 ? 155.664 118.606 82.406  1.00 72.12  ? 292 ARG B CZ  1 
ATOM   7954  N NH1 . ARG B 1 272 ? 155.840 117.756 81.407  1.00 71.85  ? 292 ARG B NH1 1 
ATOM   7955  N NH2 . ARG B 1 272 ? 154.501 119.225 82.540  1.00 72.05  ? 292 ARG B NH2 1 
ATOM   7956  N N   . LEU B 1 273 ? 157.564 116.543 88.556  1.00 67.17  ? 293 LEU B N   1 
ATOM   7957  C CA  . LEU B 1 273 ? 157.869 117.064 89.884  1.00 69.09  ? 293 LEU B CA  1 
ATOM   7958  C C   . LEU B 1 273 ? 157.492 116.047 90.965  1.00 69.69  ? 293 LEU B C   1 
ATOM   7959  O O   . LEU B 1 273 ? 157.219 116.408 92.109  1.00 69.50  ? 293 LEU B O   1 
ATOM   7960  C CB  . LEU B 1 273 ? 157.227 118.446 90.097  1.00 70.75  ? 293 LEU B CB  1 
ATOM   7961  C CG  . LEU B 1 273 ? 155.705 118.569 89.994  1.00 71.54  ? 293 LEU B CG  1 
ATOM   7962  C CD1 . LEU B 1 273 ? 155.047 118.467 91.363  1.00 72.22  ? 293 LEU B CD1 1 
ATOM   7963  C CD2 . LEU B 1 273 ? 155.318 119.884 89.320  1.00 71.03  ? 293 LEU B CD2 1 
ATOM   7964  N N   . GLY B 1 274 ? 157.514 114.763 90.592  1.00 71.75  ? 294 GLY B N   1 
ATOM   7965  C CA  . GLY B 1 274 ? 157.601 113.669 91.547  1.00 74.47  ? 294 GLY B CA  1 
ATOM   7966  C C   . GLY B 1 274 ? 156.348 113.497 92.405  1.00 77.62  ? 294 GLY B C   1 
ATOM   7967  O O   . GLY B 1 274 ? 156.386 113.704 93.617  1.00 78.66  ? 294 GLY B O   1 
ATOM   7968  N N   . LEU B 1 275 ? 155.255 113.066 91.764  1.00 80.88  ? 295 LEU B N   1 
ATOM   7969  C CA  . LEU B 1 275 ? 154.087 112.532 92.453  1.00 83.13  ? 295 LEU B CA  1 
ATOM   7970  C C   . LEU B 1 275 ? 153.804 111.120 91.938  1.00 87.91  ? 295 LEU B C   1 
ATOM   7971  O O   . LEU B 1 275 ? 153.623 110.916 90.739  1.00 87.63  ? 295 LEU B O   1 
ATOM   7972  C CB  . LEU B 1 275 ? 152.895 113.468 92.226  1.00 82.23  ? 295 LEU B CB  1 
ATOM   7973  C CG  . LEU B 1 275 ? 152.732 114.579 93.265  1.00 82.16  ? 295 LEU B CG  1 
ATOM   7974  C CD1 . LEU B 1 275 ? 153.739 115.698 93.062  1.00 80.18  ? 295 LEU B CD1 1 
ATOM   7975  C CD2 . LEU B 1 275 ? 151.318 115.140 93.229  1.00 83.33  ? 295 LEU B CD2 1 
ATOM   7976  N N   . ALA B 1 276 ? 153.778 110.150 92.863  1.00 93.07  ? 296 ALA B N   1 
ATOM   7977  C CA  . ALA B 1 276 ? 153.620 108.746 92.517  1.00 97.46  ? 296 ALA B CA  1 
ATOM   7978  C C   . ALA B 1 276 ? 152.541 108.114 93.395  1.00 97.14  ? 296 ALA B C   1 
ATOM   7979  O O   . ALA B 1 276 ? 152.786 107.145 94.117  1.00 98.73  ? 296 ALA B O   1 
ATOM   7980  C CB  . ALA B 1 276 ? 154.946 108.037 92.655  1.00 99.32  ? 296 ALA B CB  1 
ATOM   7981  N N   . GLY B 1 277 ? 151.337 108.693 93.318  1.00 92.90  ? 297 GLY B N   1 
ATOM   7982  C CA  . GLY B 1 277 ? 150.166 108.198 94.029  1.00 89.71  ? 297 GLY B CA  1 
ATOM   7983  C C   . GLY B 1 277 ? 149.771 109.083 95.210  1.00 84.49  ? 297 GLY B C   1 
ATOM   7984  O O   . GLY B 1 277 ? 149.363 108.584 96.255  1.00 84.61  ? 297 GLY B O   1 
ATOM   7985  N N   . GLU B 1 278 ? 149.859 110.402 95.015  1.00 79.04  ? 298 GLU B N   1 
ATOM   7986  C CA  . GLU B 1 278 ? 149.625 111.368 96.075  1.00 75.47  ? 298 GLU B CA  1 
ATOM   7987  C C   . GLU B 1 278 ? 148.247 112.011 95.911  1.00 67.97  ? 298 GLU B C   1 
ATOM   7988  O O   . GLU B 1 278 ? 147.666 112.512 96.873  1.00 66.30  ? 298 GLU B O   1 
ATOM   7989  C CB  . GLU B 1 278 ? 150.747 112.403 96.038  1.00 79.01  ? 298 GLU B CB  1 
ATOM   7990  C CG  . GLU B 1 278 ? 150.637 113.439 97.128  1.00 81.08  ? 298 GLU B CG  1 
ATOM   7991  C CD  . GLU B 1 278 ? 151.894 114.259 97.358  1.00 83.35  ? 298 GLU B CD  1 
ATOM   7992  O OE1 . GLU B 1 278 ? 152.343 114.935 96.411  1.00 83.82  ? 298 GLU B OE1 1 
ATOM   7993  O OE2 . GLU B 1 278 ? 152.422 114.220 98.487  1.00 84.41  ? 298 GLU B OE2 1 
ATOM   7994  N N   . PHE B 1 279 ? 147.737 112.008 94.672  1.00 62.22  ? 299 PHE B N   1 
ATOM   7995  C CA  . PHE B 1 279 ? 146.405 112.503 94.367  1.00 57.09  ? 299 PHE B CA  1 
ATOM   7996  C C   . PHE B 1 279 ? 145.521 111.360 93.882  1.00 53.58  ? 299 PHE B C   1 
ATOM   7997  O O   . PHE B 1 279 ? 145.996 110.422 93.243  1.00 53.14  ? 299 PHE B O   1 
ATOM   7998  C CB  . PHE B 1 279 ? 146.462 113.584 93.284  1.00 56.04  ? 299 PHE B CB  1 
ATOM   7999  C CG  . PHE B 1 279 ? 146.779 114.969 93.781  1.00 54.50  ? 299 PHE B CG  1 
ATOM   8000  C CD1 . PHE B 1 279 ? 145.984 115.567 94.744  1.00 55.05  ? 299 PHE B CD1 1 
ATOM   8001  C CD2 . PHE B 1 279 ? 147.863 115.676 93.282  1.00 54.26  ? 299 PHE B CD2 1 
ATOM   8002  C CE1 . PHE B 1 279 ? 146.273 116.841 95.205  1.00 56.90  ? 299 PHE B CE1 1 
ATOM   8003  C CE2 . PHE B 1 279 ? 148.150 116.952 93.743  1.00 55.86  ? 299 PHE B CE2 1 
ATOM   8004  C CZ  . PHE B 1 279 ? 147.352 117.536 94.701  1.00 57.04  ? 299 PHE B CZ  1 
ATOM   8005  N N   . LEU B 1 280 ? 144.224 111.469 94.188  1.00 50.70  ? 300 LEU B N   1 
ATOM   8006  C CA  . LEU B 1 280 ? 143.202 110.674 93.531  1.00 49.19  ? 300 LEU B CA  1 
ATOM   8007  C C   . LEU B 1 280 ? 142.506 111.554 92.498  1.00 48.18  ? 300 LEU B C   1 
ATOM   8008  O O   . LEU B 1 280 ? 141.908 112.574 92.838  1.00 47.88  ? 300 LEU B O   1 
ATOM   8009  C CB  . LEU B 1 280 ? 142.215 110.147 94.575  1.00 48.91  ? 300 LEU B CB  1 
ATOM   8010  C CG  . LEU B 1 280 ? 141.261 109.053 94.090  1.00 48.98  ? 300 LEU B CG  1 
ATOM   8011  C CD1 . LEU B 1 280 ? 140.710 108.263 95.263  1.00 49.90  ? 300 LEU B CD1 1 
ATOM   8012  C CD2 . LEU B 1 280 ? 140.100 109.618 93.288  1.00 48.88  ? 300 LEU B CD2 1 
ATOM   8013  N N   . LEU B 1 281 ? 142.605 111.152 91.226  1.00 47.16  ? 301 LEU B N   1 
ATOM   8014  C CA  . LEU B 1 281 ? 141.997 111.893 90.133  1.00 45.92  ? 301 LEU B CA  1 
ATOM   8015  C C   . LEU B 1 281 ? 140.646 111.266 89.809  1.00 44.17  ? 301 LEU B C   1 
ATOM   8016  O O   . LEU B 1 281 ? 140.590 110.149 89.295  1.00 43.75  ? 301 LEU B O   1 
ATOM   8017  C CB  . LEU B 1 281 ? 142.919 111.846 88.911  1.00 46.00  ? 301 LEU B CB  1 
ATOM   8018  C CG  . LEU B 1 281 ? 144.256 112.575 89.026  1.00 46.70  ? 301 LEU B CG  1 
ATOM   8019  C CD1 . LEU B 1 281 ? 144.988 112.535 87.695  1.00 46.70  ? 301 LEU B CD1 1 
ATOM   8020  C CD2 . LEU B 1 281 ? 144.065 114.013 89.488  1.00 47.00  ? 301 LEU B CD2 1 
ATOM   8021  N N   . LEU B 1 282 ? 139.569 111.989 90.138  1.00 42.49  ? 302 LEU B N   1 
ATOM   8022  C CA  . LEU B 1 282 ? 138.226 111.566 89.789  1.00 41.65  ? 302 LEU B CA  1 
ATOM   8023  C C   . LEU B 1 282 ? 137.889 112.127 88.410  1.00 39.83  ? 302 LEU B C   1 
ATOM   8024  O O   . LEU B 1 282 ? 137.544 113.300 88.278  1.00 40.19  ? 302 LEU B O   1 
ATOM   8025  C CB  . LEU B 1 282 ? 137.229 112.050 90.846  1.00 42.11  ? 302 LEU B CB  1 
ATOM   8026  C CG  . LEU B 1 282 ? 135.792 111.577 90.618  1.00 42.63  ? 302 LEU B CG  1 
ATOM   8027  C CD1 . LEU B 1 282 ? 135.633 110.136 91.079  1.00 42.75  ? 302 LEU B CD1 1 
ATOM   8028  C CD2 . LEU B 1 282 ? 134.781 112.488 91.296  1.00 42.49  ? 302 LEU B CD2 1 
ATOM   8029  N N   . GLY B 1 283 ? 138.001 111.271 87.390  1.00 37.26  ? 303 GLY B N   1 
ATOM   8030  C CA  . GLY B 1 283 ? 137.894 111.701 86.010  1.00 35.26  ? 303 GLY B CA  1 
ATOM   8031  C C   . GLY B 1 283 ? 136.447 111.819 85.551  1.00 33.72  ? 303 GLY B C   1 
ATOM   8032  O O   . GLY B 1 283 ? 135.518 111.823 86.359  1.00 33.49  ? 303 GLY B O   1 
ATOM   8033  N N   . SER B 1 284 ? 136.294 111.919 84.229  1.00 32.92  ? 304 SER B N   1 
ATOM   8034  C CA  . SER B 1 284 ? 135.005 112.090 83.592  1.00 32.16  ? 304 SER B CA  1 
ATOM   8035  C C   . SER B 1 284 ? 134.980 111.283 82.296  1.00 31.74  ? 304 SER B C   1 
ATOM   8036  O O   . SER B 1 284 ? 135.819 110.410 82.092  1.00 31.97  ? 304 SER B O   1 
ATOM   8037  C CB  . SER B 1 284 ? 134.742 113.547 83.353  1.00 32.27  ? 304 SER B CB  1 
ATOM   8038  O OG  . SER B 1 284 ? 133.405 113.745 82.940  1.00 32.76  ? 304 SER B OG  1 
ATOM   8039  N N   . ASP B 1 285 ? 134.021 111.590 81.418  1.00 31.33  ? 305 ASP B N   1 
ATOM   8040  C CA  . ASP B 1 285 ? 133.901 110.926 80.133  1.00 31.40  ? 305 ASP B CA  1 
ATOM   8041  C C   . ASP B 1 285 ? 135.205 111.071 79.347  1.00 30.19  ? 305 ASP B C   1 
ATOM   8042  O O   . ASP B 1 285 ? 135.628 110.133 78.676  1.00 30.49  ? 305 ASP B O   1 
ATOM   8043  C CB  . ASP B 1 285 ? 132.705 111.502 79.373  1.00 33.28  ? 305 ASP B CB  1 
ATOM   8044  C CG  . ASP B 1 285 ? 132.555 110.988 77.958  1.00 35.89  ? 305 ASP B CG  1 
ATOM   8045  O OD1 . ASP B 1 285 ? 133.339 110.107 77.579  1.00 36.98  ? 305 ASP B OD1 1 
ATOM   8046  O OD2 . ASP B 1 285 ? 131.651 111.481 77.250  1.00 36.99  ? 305 ASP B OD2 1 
ATOM   8047  N N   . GLY B 1 286 ? 135.857 112.232 79.479  1.00 28.70  ? 306 GLY B N   1 
ATOM   8048  C CA  . GLY B 1 286 ? 137.084 112.526 78.758  1.00 27.66  ? 306 GLY B CA  1 
ATOM   8049  C C   . GLY B 1 286 ? 138.176 111.497 79.033  1.00 26.51  ? 306 GLY B C   1 
ATOM   8050  O O   . GLY B 1 286 ? 138.862 111.054 78.117  1.00 26.70  ? 306 GLY B O   1 
ATOM   8051  N N   . TRP B 1 287 ? 138.311 111.098 80.299  1.00 25.12  ? 307 TRP B N   1 
ATOM   8052  C CA  . TRP B 1 287 ? 139.283 110.089 80.670  1.00 24.31  ? 307 TRP B CA  1 
ATOM   8053  C C   . TRP B 1 287 ? 138.730 108.699 80.357  1.00 24.62  ? 307 TRP B C   1 
ATOM   8054  O O   . TRP B 1 287 ? 139.310 107.969 79.558  1.00 24.93  ? 307 TRP B O   1 
ATOM   8055  C CB  . TRP B 1 287 ? 139.668 110.260 82.141  1.00 23.77  ? 307 TRP B CB  1 
ATOM   8056  C CG  . TRP B 1 287 ? 140.767 109.358 82.606  1.00 23.50  ? 307 TRP B CG  1 
ATOM   8057  C CD1 . TRP B 1 287 ? 141.361 108.334 81.926  1.00 23.48  ? 307 TRP B CD1 1 
ATOM   8058  C CD2 . TRP B 1 287 ? 141.416 109.412 83.886  1.00 23.25  ? 307 TRP B CD2 1 
ATOM   8059  N NE1 . TRP B 1 287 ? 142.326 107.748 82.697  1.00 23.33  ? 307 TRP B NE1 1 
ATOM   8060  C CE2 . TRP B 1 287 ? 142.385 108.390 83.902  1.00 23.30  ? 307 TRP B CE2 1 
ATOM   8061  C CE3 . TRP B 1 287 ? 141.272 110.224 85.013  1.00 23.39  ? 307 TRP B CE3 1 
ATOM   8062  C CZ2 . TRP B 1 287 ? 143.201 108.157 85.004  1.00 23.70  ? 307 TRP B CZ2 1 
ATOM   8063  C CZ3 . TRP B 1 287 ? 142.079 109.994 86.103  1.00 23.77  ? 307 TRP B CZ3 1 
ATOM   8064  C CH2 . TRP B 1 287 ? 143.029 108.971 86.098  1.00 23.97  ? 307 TRP B CH2 1 
ATOM   8065  N N   . ALA B 1 288 ? 137.616 108.337 81.003  1.00 24.90  ? 308 ALA B N   1 
ATOM   8066  C CA  . ALA B 1 288 ? 136.931 107.078 80.750  1.00 25.30  ? 308 ALA B CA  1 
ATOM   8067  C C   . ALA B 1 288 ? 137.903 105.905 80.881  1.00 25.67  ? 308 ALA B C   1 
ATOM   8068  O O   . ALA B 1 288 ? 138.567 105.772 81.908  1.00 25.85  ? 308 ALA B O   1 
ATOM   8069  C CB  . ALA B 1 288 ? 136.257 107.125 79.399  1.00 25.52  ? 308 ALA B CB  1 
ATOM   8070  N N   . ASP B 1 289 ? 137.982 105.044 79.856  1.00 26.39  ? 309 ASP B N   1 
ATOM   8071  C CA  . ASP B 1 289 ? 138.832 103.869 79.939  1.00 27.61  ? 309 ASP B CA  1 
ATOM   8072  C C   . ASP B 1 289 ? 139.999 103.996 78.966  1.00 28.42  ? 309 ASP B C   1 
ATOM   8073  O O   . ASP B 1 289 ? 140.696 103.015 78.710  1.00 29.04  ? 309 ASP B O   1 
ATOM   8074  C CB  . ASP B 1 289 ? 138.048 102.579 79.705  1.00 28.87  ? 309 ASP B CB  1 
ATOM   8075  C CG  . ASP B 1 289 ? 137.803 102.264 78.244  1.00 30.85  ? 309 ASP B CG  1 
ATOM   8076  O OD1 . ASP B 1 289 ? 138.723 101.729 77.590  1.00 32.24  ? 309 ASP B OD1 1 
ATOM   8077  O OD2 . ASP B 1 289 ? 136.693 102.560 77.773  1.00 31.66  ? 309 ASP B OD2 1 
ATOM   8078  N N   . ARG B 1 290 ? 140.223 105.204 78.443  1.00 29.06  ? 310 ARG B N   1 
ATOM   8079  C CA  . ARG B 1 290 ? 141.217 105.412 77.400  1.00 29.83  ? 310 ARG B CA  1 
ATOM   8080  C C   . ARG B 1 290 ? 142.609 105.042 77.897  1.00 31.28  ? 310 ARG B C   1 
ATOM   8081  O O   . ARG B 1 290 ? 143.017 105.465 78.974  1.00 31.10  ? 310 ARG B O   1 
ATOM   8082  C CB  . ARG B 1 290 ? 141.214 106.870 76.939  1.00 29.85  ? 310 ARG B CB  1 
ATOM   8083  C CG  . ARG B 1 290 ? 139.851 107.336 76.454  1.00 29.95  ? 310 ARG B CG  1 
ATOM   8084  C CD  . ARG B 1 290 ? 139.938 108.208 75.217  1.00 30.04  ? 310 ARG B CD  1 
ATOM   8085  N NE  . ARG B 1 290 ? 140.298 109.584 75.516  1.00 29.74  ? 310 ARG B NE  1 
ATOM   8086  C CZ  . ARG B 1 290 ? 141.145 110.330 74.817  1.00 30.05  ? 310 ARG B CZ  1 
ATOM   8087  N NH1 . ARG B 1 290 ? 141.823 109.822 73.801  1.00 30.36  ? 310 ARG B NH1 1 
ATOM   8088  N NH2 . ARG B 1 290 ? 141.295 111.604 75.128  1.00 30.22  ? 310 ARG B NH2 1 
ATOM   8089  N N   . TYR B 1 291 ? 143.332 104.264 77.087  1.00 33.44  ? 311 TYR B N   1 
ATOM   8090  C CA  . TYR B 1 291 ? 144.694 103.873 77.410  1.00 35.33  ? 311 TYR B CA  1 
ATOM   8091  C C   . TYR B 1 291 ? 145.684 104.935 76.949  1.00 36.17  ? 311 TYR B C   1 
ATOM   8092  O O   . TYR B 1 291 ? 146.758 105.055 77.525  1.00 36.95  ? 311 TYR B O   1 
ATOM   8093  C CB  . TYR B 1 291 ? 145.044 102.525 76.780  1.00 36.73  ? 311 TYR B CB  1 
ATOM   8094  C CG  . TYR B 1 291 ? 144.412 101.348 77.471  1.00 38.85  ? 311 TYR B CG  1 
ATOM   8095  C CD1 . TYR B 1 291 ? 144.626 101.119 78.819  1.00 40.13  ? 311 TYR B CD1 1 
ATOM   8096  C CD2 . TYR B 1 291 ? 143.602 100.462 76.783  1.00 40.91  ? 311 TYR B CD2 1 
ATOM   8097  C CE1 . TYR B 1 291 ? 144.040 100.049 79.471  1.00 41.48  ? 311 TYR B CE1 1 
ATOM   8098  C CE2 . TYR B 1 291 ? 143.017 99.377  77.415  1.00 42.24  ? 311 TYR B CE2 1 
ATOM   8099  C CZ  . TYR B 1 291 ? 143.239 99.168  78.765  1.00 42.68  ? 311 TYR B CZ  1 
ATOM   8100  O OH  . TYR B 1 291 ? 142.665 98.094  79.407  1.00 43.83  ? 311 TYR B OH  1 
ATOM   8101  N N   . ASP B 1 292 ? 145.293 105.753 75.967  1.00 37.33  ? 312 ASP B N   1 
ATOM   8102  C CA  . ASP B 1 292 ? 146.198 106.717 75.359  1.00 38.20  ? 312 ASP B CA  1 
ATOM   8103  C C   . ASP B 1 292 ? 146.498 107.866 76.322  1.00 36.74  ? 312 ASP B C   1 
ATOM   8104  O O   . ASP B 1 292 ? 147.434 108.629 76.102  1.00 37.18  ? 312 ASP B O   1 
ATOM   8105  C CB  . ASP B 1 292 ? 145.612 107.247 74.050  1.00 40.09  ? 312 ASP B CB  1 
ATOM   8106  C CG  . ASP B 1 292 ? 145.216 106.139 73.090  1.00 41.99  ? 312 ASP B CG  1 
ATOM   8107  O OD1 . ASP B 1 292 ? 146.128 105.456 72.578  1.00 42.88  ? 312 ASP B OD1 1 
ATOM   8108  O OD2 . ASP B 1 292 ? 143.998 105.942 72.899  1.00 42.75  ? 312 ASP B OD2 1 
ATOM   8109  N N   . VAL B 1 293 ? 145.697 107.988 77.385  1.00 34.99  ? 313 VAL B N   1 
ATOM   8110  C CA  . VAL B 1 293 ? 145.875 109.058 78.347  1.00 34.46  ? 313 VAL B CA  1 
ATOM   8111  C C   . VAL B 1 293 ? 146.770 108.594 79.492  1.00 35.06  ? 313 VAL B C   1 
ATOM   8112  O O   . VAL B 1 293 ? 147.265 109.428 80.242  1.00 35.47  ? 313 VAL B O   1 
ATOM   8113  C CB  . VAL B 1 293 ? 144.523 109.572 78.876  1.00 33.81  ? 313 VAL B CB  1 
ATOM   8114  C CG1 . VAL B 1 293 ? 143.611 110.037 77.752  1.00 33.78  ? 313 VAL B CG1 1 
ATOM   8115  C CG2 . VAL B 1 293 ? 143.811 108.542 79.728  1.00 34.29  ? 313 VAL B CG2 1 
ATOM   8116  N N   . THR B 1 294 ? 146.950 107.280 79.660  1.00 36.30  ? 314 THR B N   1 
ATOM   8117  C CA  . THR B 1 294 ? 147.745 106.769 80.769  1.00 37.57  ? 314 THR B CA  1 
ATOM   8118  C C   . THR B 1 294 ? 148.874 105.855 80.294  1.00 41.47  ? 314 THR B C   1 
ATOM   8119  O O   . THR B 1 294 ? 149.614 105.333 81.122  1.00 43.29  ? 314 THR B O   1 
ATOM   8120  C CB  . THR B 1 294 ? 146.871 106.032 81.791  1.00 36.00  ? 314 THR B CB  1 
ATOM   8121  O OG1 . THR B 1 294 ? 146.083 105.073 81.087  1.00 35.99  ? 314 THR B OG1 1 
ATOM   8122  C CG2 . THR B 1 294 ? 145.967 106.963 82.566  1.00 35.63  ? 314 THR B CG2 1 
ATOM   8123  N N   . ASP B 1 295 ? 149.018 105.664 78.977  1.00 45.16  ? 315 ASP B N   1 
ATOM   8124  C CA  . ASP B 1 295 ? 150.082 104.824 78.458  1.00 48.27  ? 315 ASP B CA  1 
ATOM   8125  C C   . ASP B 1 295 ? 151.416 105.504 78.735  1.00 48.85  ? 315 ASP B C   1 
ATOM   8126  O O   . ASP B 1 295 ? 151.562 106.703 78.504  1.00 48.64  ? 315 ASP B O   1 
ATOM   8127  C CB  . ASP B 1 295 ? 149.902 104.524 76.967  1.00 51.48  ? 315 ASP B CB  1 
ATOM   8128  C CG  . ASP B 1 295 ? 149.224 103.196 76.671  1.00 54.14  ? 315 ASP B CG  1 
ATOM   8129  O OD1 . ASP B 1 295 ? 149.171 102.337 77.582  1.00 55.15  ? 315 ASP B OD1 1 
ATOM   8130  O OD2 . ASP B 1 295 ? 148.759 103.023 75.523  1.00 55.65  ? 315 ASP B OD2 1 
ATOM   8131  N N   . GLY B 1 296 ? 152.364 104.722 79.262  1.00 50.53  ? 316 GLY B N   1 
ATOM   8132  C CA  . GLY B 1 296 ? 153.670 105.232 79.628  1.00 52.25  ? 316 GLY B CA  1 
ATOM   8133  C C   . GLY B 1 296 ? 153.694 105.834 81.032  1.00 53.22  ? 316 GLY B C   1 
ATOM   8134  O O   . GLY B 1 296 ? 154.701 105.711 81.724  1.00 54.78  ? 316 GLY B O   1 
ATOM   8135  N N   . TYR B 1 297 ? 152.601 106.496 81.443  1.00 52.84  ? 317 TYR B N   1 
ATOM   8136  C CA  . TYR B 1 297 ? 152.562 107.185 82.724  1.00 52.92  ? 317 TYR B CA  1 
ATOM   8137  C C   . TYR B 1 297 ? 151.535 106.534 83.650  1.00 51.27  ? 317 TYR B C   1 
ATOM   8138  O O   . TYR B 1 297 ? 150.792 107.226 84.349  1.00 49.99  ? 317 TYR B O   1 
ATOM   8139  C CB  . TYR B 1 297 ? 152.258 108.668 82.508  1.00 55.15  ? 317 TYR B CB  1 
ATOM   8140  C CG  . TYR B 1 297 ? 153.330 109.467 81.805  1.00 59.00  ? 317 TYR B CG  1 
ATOM   8141  C CD1 . TYR B 1 297 ? 154.110 108.940 80.786  1.00 61.10  ? 317 TYR B CD1 1 
ATOM   8142  C CD2 . TYR B 1 297 ? 153.525 110.800 82.126  1.00 61.13  ? 317 TYR B CD2 1 
ATOM   8143  C CE1 . TYR B 1 297 ? 155.071 109.691 80.132  1.00 64.60  ? 317 TYR B CE1 1 
ATOM   8144  C CE2 . TYR B 1 297 ? 154.481 111.569 81.477  1.00 63.10  ? 317 TYR B CE2 1 
ATOM   8145  C CZ  . TYR B 1 297 ? 155.258 111.015 80.478  1.00 65.81  ? 317 TYR B CZ  1 
ATOM   8146  O OH  . TYR B 1 297 ? 156.207 111.779 79.842  1.00 66.73  ? 317 TYR B OH  1 
ATOM   8147  N N   . GLN B 1 298 ? 151.554 105.196 83.694  1.00 51.14  ? 318 GLN B N   1 
ATOM   8148  C CA  . GLN B 1 298 ? 150.576 104.429 84.447  1.00 51.75  ? 318 GLN B CA  1 
ATOM   8149  C C   . GLN B 1 298 ? 150.766 104.637 85.948  1.00 53.70  ? 318 GLN B C   1 
ATOM   8150  O O   . GLN B 1 298 ? 149.789 104.683 86.686  1.00 54.65  ? 318 GLN B O   1 
ATOM   8151  C CB  . GLN B 1 298 ? 150.667 102.935 84.129  1.00 51.06  ? 318 GLN B CB  1 
ATOM   8152  C CG  . GLN B 1 298 ? 150.296 102.580 82.698  1.00 51.68  ? 318 GLN B CG  1 
ATOM   8153  C CD  . GLN B 1 298 ? 151.501 102.245 81.853  1.00 53.19  ? 318 GLN B CD  1 
ATOM   8154  O OE1 . GLN B 1 298 ? 152.536 102.905 81.913  1.00 53.32  ? 318 GLN B OE1 1 
ATOM   8155  N NE2 . GLN B 1 298 ? 151.387 101.182 81.071  1.00 54.17  ? 318 GLN B NE2 1 
ATOM   8156  N N   . ARG B 1 299 ? 152.020 104.778 86.391  1.00 54.56  ? 319 ARG B N   1 
ATOM   8157  C CA  . ARG B 1 299 ? 152.336 104.831 87.810  1.00 55.18  ? 319 ARG B CA  1 
ATOM   8158  C C   . ARG B 1 299 ? 151.696 106.050 88.475  1.00 53.01  ? 319 ARG B C   1 
ATOM   8159  O O   . ARG B 1 299 ? 151.503 106.046 89.690  1.00 52.74  ? 319 ARG B O   1 
ATOM   8160  C CB  . ARG B 1 299 ? 153.852 104.865 88.018  1.00 58.92  ? 319 ARG B CB  1 
ATOM   8161  C CG  . ARG B 1 299 ? 154.298 104.397 89.395  1.00 62.21  ? 319 ARG B CG  1 
ATOM   8162  C CD  . ARG B 1 299 ? 154.300 102.889 89.487  1.00 64.66  ? 319 ARG B CD  1 
ATOM   8163  N NE  . ARG B 1 299 ? 155.232 102.339 88.512  1.00 67.78  ? 319 ARG B NE  1 
ATOM   8164  C CZ  . ARG B 1 299 ? 155.413 101.046 88.274  1.00 71.06  ? 319 ARG B CZ  1 
ATOM   8165  N NH1 . ARG B 1 299 ? 154.818 100.133 89.024  1.00 71.53  ? 319 ARG B NH1 1 
ATOM   8166  N NH2 . ARG B 1 299 ? 156.213 100.665 87.291  1.00 71.61  ? 319 ARG B NH2 1 
ATOM   8167  N N   . GLU B 1 300 ? 151.360 107.083 87.688  1.00 51.93  ? 320 GLU B N   1 
ATOM   8168  C CA  . GLU B 1 300 ? 150.913 108.353 88.243  1.00 52.07  ? 320 GLU B CA  1 
ATOM   8169  C C   . GLU B 1 300 ? 149.388 108.434 88.340  1.00 49.31  ? 320 GLU B C   1 
ATOM   8170  O O   . GLU B 1 300 ? 148.873 109.299 89.046  1.00 48.88  ? 320 GLU B O   1 
ATOM   8171  C CB  . GLU B 1 300 ? 151.426 109.533 87.415  1.00 54.33  ? 320 GLU B CB  1 
ATOM   8172  C CG  . GLU B 1 300 ? 152.820 110.006 87.790  1.00 56.85  ? 320 GLU B CG  1 
ATOM   8173  C CD  . GLU B 1 300 ? 153.964 109.364 87.023  1.00 58.69  ? 320 GLU B CD  1 
ATOM   8174  O OE1 . GLU B 1 300 ? 155.131 109.607 87.399  1.00 58.75  ? 320 GLU B OE1 1 
ATOM   8175  O OE2 . GLU B 1 300 ? 153.692 108.643 86.036  1.00 59.81  ? 320 GLU B OE2 1 
ATOM   8176  N N   . ALA B 1 301 ? 148.678 107.547 87.629  1.00 46.70  ? 321 ALA B N   1 
ATOM   8177  C CA  . ALA B 1 301 ? 147.226 107.597 87.575  1.00 44.56  ? 321 ALA B CA  1 
ATOM   8178  C C   . ALA B 1 301 ? 146.591 106.414 88.303  1.00 43.56  ? 321 ALA B C   1 
ATOM   8179  O O   . ALA B 1 301 ? 145.372 106.252 88.251  1.00 43.86  ? 321 ALA B O   1 
ATOM   8180  C CB  . ALA B 1 301 ? 146.787 107.623 86.138  1.00 43.95  ? 321 ALA B CB  1 
ATOM   8181  N N   . VAL B 1 302 ? 147.407 105.582 88.962  1.00 41.92  ? 322 VAL B N   1 
ATOM   8182  C CA  . VAL B 1 302 ? 146.880 104.423 89.665  1.00 40.68  ? 322 VAL B CA  1 
ATOM   8183  C C   . VAL B 1 302 ? 145.932 104.907 90.760  1.00 39.59  ? 322 VAL B C   1 
ATOM   8184  O O   . VAL B 1 302 ? 146.240 105.851 91.480  1.00 39.25  ? 322 VAL B O   1 
ATOM   8185  C CB  . VAL B 1 302 ? 147.997 103.519 90.225  1.00 41.70  ? 322 VAL B CB  1 
ATOM   8186  C CG1 . VAL B 1 302 ? 148.943 104.248 91.174  1.00 42.49  ? 322 VAL B CG1 1 
ATOM   8187  C CG2 . VAL B 1 302 ? 147.424 102.280 90.895  1.00 42.57  ? 322 VAL B CG2 1 
ATOM   8188  N N   . GLY B 1 303 ? 144.768 104.256 90.858  1.00 39.29  ? 323 GLY B N   1 
ATOM   8189  C CA  . GLY B 1 303 ? 143.778 104.580 91.871  1.00 39.20  ? 323 GLY B CA  1 
ATOM   8190  C C   . GLY B 1 303 ? 142.717 105.563 91.377  1.00 38.39  ? 323 GLY B C   1 
ATOM   8191  O O   . GLY B 1 303 ? 141.697 105.743 92.040  1.00 38.43  ? 323 GLY B O   1 
ATOM   8192  N N   . GLY B 1 304 ? 142.961 106.201 90.224  1.00 36.68  ? 324 GLY B N   1 
ATOM   8193  C CA  . GLY B 1 304 ? 142.023 107.163 89.662  1.00 34.98  ? 324 GLY B CA  1 
ATOM   8194  C C   . GLY B 1 304 ? 140.688 106.511 89.309  1.00 33.22  ? 324 GLY B C   1 
ATOM   8195  O O   . GLY B 1 304 ? 140.667 105.396 88.793  1.00 33.19  ? 324 GLY B O   1 
ATOM   8196  N N   . ILE B 1 305 ? 139.587 107.218 89.598  1.00 31.55  ? 325 ILE B N   1 
ATOM   8197  C CA  . ILE B 1 305 ? 138.246 106.720 89.329  1.00 30.33  ? 325 ILE B CA  1 
ATOM   8198  C C   . ILE B 1 305 ? 137.635 107.564 88.216  1.00 28.70  ? 325 ILE B C   1 
ATOM   8199  O O   . ILE B 1 305 ? 137.621 108.785 88.304  1.00 29.15  ? 325 ILE B O   1 
ATOM   8200  C CB  . ILE B 1 305 ? 137.382 106.731 90.607  1.00 30.88  ? 325 ILE B CB  1 
ATOM   8201  C CG1 . ILE B 1 305 ? 138.034 105.897 91.715  1.00 30.88  ? 325 ILE B CG1 1 
ATOM   8202  C CG2 . ILE B 1 305 ? 135.962 106.264 90.307  1.00 31.18  ? 325 ILE B CG2 1 
ATOM   8203  C CD1 . ILE B 1 305 ? 137.282 105.872 93.025  1.00 31.01  ? 325 ILE B CD1 1 
ATOM   8204  N N   . THR B 1 306 ? 137.115 106.899 87.181  1.00 27.30  ? 326 THR B N   1 
ATOM   8205  C CA  . THR B 1 306 ? 136.604 107.576 86.001  1.00 26.51  ? 326 THR B CA  1 
ATOM   8206  C C   . THR B 1 306 ? 135.173 107.126 85.729  1.00 26.23  ? 326 THR B C   1 
ATOM   8207  O O   . THR B 1 306 ? 134.727 106.111 86.263  1.00 26.68  ? 326 THR B O   1 
ATOM   8208  C CB  . THR B 1 306 ? 137.486 107.299 84.779  1.00 26.50  ? 326 THR B CB  1 
ATOM   8209  O OG1 . THR B 1 306 ? 137.217 105.971 84.327  1.00 26.61  ? 326 THR B OG1 1 
ATOM   8210  C CG2 . THR B 1 306 ? 138.962 107.451 85.074  1.00 26.76  ? 326 THR B CG2 1 
ATOM   8211  N N   . ILE B 1 307 ? 134.485 107.887 84.872  1.00 25.82  ? 327 ILE B N   1 
ATOM   8212  C CA  . ILE B 1 307 ? 133.118 107.598 84.482  1.00 25.49  ? 327 ILE B CA  1 
ATOM   8213  C C   . ILE B 1 307 ? 133.076 107.398 82.972  1.00 25.49  ? 327 ILE B C   1 
ATOM   8214  O O   . ILE B 1 307 ? 133.387 108.311 82.214  1.00 26.39  ? 327 ILE B O   1 
ATOM   8215  C CB  . ILE B 1 307 ? 132.179 108.731 84.931  1.00 25.52  ? 327 ILE B CB  1 
ATOM   8216  C CG1 . ILE B 1 307 ? 132.348 109.015 86.423  1.00 25.49  ? 327 ILE B CG1 1 
ATOM   8217  C CG2 . ILE B 1 307 ? 130.733 108.419 84.567  1.00 25.87  ? 327 ILE B CG2 1 
ATOM   8218  C CD1 . ILE B 1 307 ? 131.348 109.996 86.967  1.00 25.84  ? 327 ILE B CD1 1 
ATOM   8219  N N   . LYS B 1 308 ? 132.656 106.203 82.556  1.00 25.66  ? 328 LYS B N   1 
ATOM   8220  C CA  . LYS B 1 308 ? 132.640 105.826 81.156  1.00 26.43  ? 328 LYS B CA  1 
ATOM   8221  C C   . LYS B 1 308 ? 131.205 105.551 80.722  1.00 27.67  ? 328 LYS B C   1 
ATOM   8222  O O   . LYS B 1 308 ? 130.515 104.769 81.364  1.00 28.57  ? 328 LYS B O   1 
ATOM   8223  C CB  . LYS B 1 308 ? 133.498 104.574 80.963  1.00 26.21  ? 328 LYS B CB  1 
ATOM   8224  C CG  . LYS B 1 308 ? 133.202 103.788 79.698  1.00 26.42  ? 328 LYS B CG  1 
ATOM   8225  C CD  . LYS B 1 308 ? 133.949 102.487 79.615  1.00 27.08  ? 328 LYS B CD  1 
ATOM   8226  C CE  . LYS B 1 308 ? 133.723 101.767 78.302  1.00 28.10  ? 328 LYS B CE  1 
ATOM   8227  N NZ  . LYS B 1 308 ? 132.294 101.421 78.100  1.00 28.71  ? 328 LYS B NZ  1 
ATOM   8228  N N   . LEU B 1 309 ? 130.771 106.162 79.616  1.00 29.05  ? 329 LEU B N   1 
ATOM   8229  C CA  . LEU B 1 309 ? 129.476 105.849 79.035  1.00 30.24  ? 329 LEU B CA  1 
ATOM   8230  C C   . LEU B 1 309 ? 129.446 104.386 78.603  1.00 31.42  ? 329 LEU B C   1 
ATOM   8231  O O   . LEU B 1 309 ? 130.330 103.930 77.885  1.00 31.55  ? 329 LEU B O   1 
ATOM   8232  C CB  . LEU B 1 309 ? 129.214 106.779 77.847  1.00 30.78  ? 329 LEU B CB  1 
ATOM   8233  C CG  . LEU B 1 309 ? 128.420 108.038 78.178  1.00 31.09  ? 329 LEU B CG  1 
ATOM   8234  C CD1 . LEU B 1 309 ? 128.419 109.004 77.004  1.00 31.42  ? 329 LEU B CD1 1 
ATOM   8235  C CD2 . LEU B 1 309 ? 126.996 107.671 78.567  1.00 31.26  ? 329 LEU B CD2 1 
ATOM   8236  N N   . GLN B 1 310 ? 128.419 103.656 79.052  1.00 33.82  ? 330 GLN B N   1 
ATOM   8237  C CA  . GLN B 1 310 ? 128.337 102.228 78.800  1.00 36.83  ? 330 GLN B CA  1 
ATOM   8238  C C   . GLN B 1 310 ? 128.003 101.991 77.331  1.00 39.71  ? 330 GLN B C   1 
ATOM   8239  O O   . GLN B 1 310 ? 127.001 102.501 76.835  1.00 40.08  ? 330 GLN B O   1 
ATOM   8240  C CB  . GLN B 1 310 ? 127.291 101.570 79.699  1.00 37.83  ? 330 GLN B CB  1 
ATOM   8241  C CG  . GLN B 1 310 ? 126.878 100.185 79.219  1.00 39.16  ? 330 GLN B CG  1 
ATOM   8242  C CD  . GLN B 1 310 ? 126.196 99.359  80.285  1.00 40.53  ? 330 GLN B CD  1 
ATOM   8243  O OE1 . GLN B 1 310 ? 126.073 99.761  81.441  1.00 40.93  ? 330 GLN B OE1 1 
ATOM   8244  N NE2 . GLN B 1 310 ? 125.757 98.171  79.902  1.00 41.27  ? 330 GLN B NE2 1 
ATOM   8245  N N   . SER B 1 311 ? 128.843 101.195 76.661  1.00 43.60  ? 331 SER B N   1 
ATOM   8246  C CA  . SER B 1 311 ? 128.613 100.806 75.278  1.00 47.43  ? 331 SER B CA  1 
ATOM   8247  C C   . SER B 1 311 ? 129.341 99.497  74.984  1.00 51.02  ? 331 SER B C   1 
ATOM   8248  O O   . SER B 1 311 ? 130.567 99.449  75.039  1.00 52.62  ? 331 SER B O   1 
ATOM   8249  C CB  . SER B 1 311 ? 129.055 101.887 74.330  1.00 47.86  ? 331 SER B CB  1 
ATOM   8250  O OG  . SER B 1 311 ? 130.441 102.145 74.479  1.00 48.17  ? 331 SER B OG  1 
ATOM   8251  N N   . PRO B 1 312 ? 128.620 98.395  74.673  1.00 54.92  ? 332 PRO B N   1 
ATOM   8252  C CA  . PRO B 1 312 ? 129.260 97.111  74.392  1.00 57.46  ? 332 PRO B CA  1 
ATOM   8253  C C   . PRO B 1 312 ? 130.069 97.156  73.099  1.00 58.97  ? 332 PRO B C   1 
ATOM   8254  O O   . PRO B 1 312 ? 129.739 97.903  72.180  1.00 59.43  ? 332 PRO B O   1 
ATOM   8255  C CB  . PRO B 1 312 ? 128.100 96.109  74.258  1.00 58.31  ? 332 PRO B CB  1 
ATOM   8256  C CG  . PRO B 1 312 ? 126.871 96.839  74.775  1.00 57.73  ? 332 PRO B CG  1 
ATOM   8257  C CD  . PRO B 1 312 ? 127.157 98.315  74.589  1.00 56.16  ? 332 PRO B CD  1 
ATOM   8258  N N   . ASP B 1 313 ? 131.143 96.360  73.053  1.00 60.28  ? 333 ASP B N   1 
ATOM   8259  C CA  . ASP B 1 313 ? 132.034 96.333  71.905  1.00 62.52  ? 333 ASP B CA  1 
ATOM   8260  C C   . ASP B 1 313 ? 131.282 95.782  70.698  1.00 60.94  ? 333 ASP B C   1 
ATOM   8261  O O   . ASP B 1 313 ? 130.555 94.797  70.809  1.00 61.88  ? 333 ASP B O   1 
ATOM   8262  C CB  . ASP B 1 313 ? 133.287 95.501  72.187  1.00 66.48  ? 333 ASP B CB  1 
ATOM   8263  C CG  . ASP B 1 313 ? 134.246 96.137  73.180  1.00 70.77  ? 333 ASP B CG  1 
ATOM   8264  O OD1 . ASP B 1 313 ? 134.066 97.333  73.494  1.00 72.23  ? 333 ASP B OD1 1 
ATOM   8265  O OD2 . ASP B 1 313 ? 135.152 95.425  73.648  1.00 72.85  ? 333 ASP B OD2 1 
ATOM   8266  N N   . VAL B 1 314 ? 131.469 96.436  69.549  1.00 59.39  ? 334 VAL B N   1 
ATOM   8267  C CA  . VAL B 1 314 ? 130.838 96.021  68.308  1.00 59.25  ? 334 VAL B CA  1 
ATOM   8268  C C   . VAL B 1 314 ? 131.757 95.017  67.619  1.00 61.16  ? 334 VAL B C   1 
ATOM   8269  O O   . VAL B 1 314 ? 132.826 95.386  67.138  1.00 61.37  ? 334 VAL B O   1 
ATOM   8270  C CB  . VAL B 1 314 ? 130.554 97.233  67.404  1.00 58.00  ? 334 VAL B CB  1 
ATOM   8271  C CG1 . VAL B 1 314 ? 129.788 96.828  66.155  1.00 58.44  ? 334 VAL B CG1 1 
ATOM   8272  C CG2 . VAL B 1 314 ? 129.818 98.331  68.154  1.00 57.09  ? 334 VAL B CG2 1 
ATOM   8273  N N   . LYS B 1 315 ? 131.327 93.753  67.557  1.00 63.32  ? 335 LYS B N   1 
ATOM   8274  C CA  . LYS B 1 315 ? 132.213 92.669  67.165  1.00 66.22  ? 335 LYS B CA  1 
ATOM   8275  C C   . LYS B 1 315 ? 132.511 92.719  65.666  1.00 64.18  ? 335 LYS B C   1 
ATOM   8276  O O   . LYS B 1 315 ? 133.650 92.511  65.257  1.00 64.67  ? 335 LYS B O   1 
ATOM   8277  C CB  . LYS B 1 315 ? 131.615 91.312  67.544  1.00 70.94  ? 335 LYS B CB  1 
ATOM   8278  C CG  . LYS B 1 315 ? 132.517 90.124  67.237  1.00 75.59  ? 335 LYS B CG  1 
ATOM   8279  C CD  . LYS B 1 315 ? 131.921 88.783  67.603  1.00 79.62  ? 335 LYS B CD  1 
ATOM   8280  C CE  . LYS B 1 315 ? 132.825 87.622  67.243  1.00 81.86  ? 335 LYS B CE  1 
ATOM   8281  N NZ  . LYS B 1 315 ? 133.067 87.540  65.781  1.00 82.35  ? 335 LYS B NZ  1 
ATOM   8282  N N   . TRP B 1 316 ? 131.485 92.961  64.847  1.00 61.11  ? 336 TRP B N   1 
ATOM   8283  C CA  . TRP B 1 316 ? 131.654 92.922  63.402  1.00 59.46  ? 336 TRP B CA  1 
ATOM   8284  C C   . TRP B 1 316 ? 132.567 94.052  62.933  1.00 57.35  ? 336 TRP B C   1 
ATOM   8285  O O   . TRP B 1 316 ? 133.255 93.906  61.924  1.00 57.98  ? 336 TRP B O   1 
ATOM   8286  C CB  . TRP B 1 316 ? 130.303 92.938  62.680  1.00 59.85  ? 336 TRP B CB  1 
ATOM   8287  C CG  . TRP B 1 316 ? 129.390 94.062  63.060  1.00 59.85  ? 336 TRP B CG  1 
ATOM   8288  C CD1 . TRP B 1 316 ? 128.334 93.989  63.921  1.00 59.76  ? 336 TRP B CD1 1 
ATOM   8289  C CD2 . TRP B 1 316 ? 129.405 95.410  62.554  1.00 59.85  ? 336 TRP B CD2 1 
ATOM   8290  N NE1 . TRP B 1 316 ? 127.704 95.199  64.006  1.00 59.96  ? 336 TRP B NE1 1 
ATOM   8291  C CE2 . TRP B 1 316 ? 128.330 96.087  63.173  1.00 59.82  ? 336 TRP B CE2 1 
ATOM   8292  C CE3 . TRP B 1 316 ? 130.215 96.115  61.655  1.00 59.67  ? 336 TRP B CE3 1 
ATOM   8293  C CZ2 . TRP B 1 316 ? 128.053 97.430  62.925  1.00 59.24  ? 336 TRP B CZ2 1 
ATOM   8294  C CZ3 . TRP B 1 316 ? 129.937 97.443  61.411  1.00 59.52  ? 336 TRP B CZ3 1 
ATOM   8295  C CH2 . TRP B 1 316 ? 128.867 98.087  62.033  1.00 59.14  ? 336 TRP B CH2 1 
ATOM   8296  N N   . PHE B 1 317 ? 132.587 95.169  63.670  1.00 54.25  ? 337 PHE B N   1 
ATOM   8297  C CA  . PHE B 1 317 ? 133.525 96.240  63.371  1.00 52.18  ? 337 PHE B CA  1 
ATOM   8298  C C   . PHE B 1 317 ? 134.962 95.738  63.530  1.00 53.09  ? 337 PHE B C   1 
ATOM   8299  O O   . PHE B 1 317 ? 135.817 96.031  62.697  1.00 53.74  ? 337 PHE B O   1 
ATOM   8300  C CB  . PHE B 1 317 ? 133.294 97.472  64.249  1.00 49.53  ? 337 PHE B CB  1 
ATOM   8301  C CG  . PHE B 1 317 ? 134.406 98.483  64.133  1.00 46.92  ? 337 PHE B CG  1 
ATOM   8302  C CD1 . PHE B 1 317 ? 134.658 99.130  62.932  1.00 45.35  ? 337 PHE B CD1 1 
ATOM   8303  C CD2 . PHE B 1 317 ? 135.247 98.735  65.204  1.00 46.07  ? 337 PHE B CD2 1 
ATOM   8304  C CE1 . PHE B 1 317 ? 135.705 100.031 62.820  1.00 44.88  ? 337 PHE B CE1 1 
ATOM   8305  C CE2 . PHE B 1 317 ? 136.290 99.641  65.092  1.00 45.72  ? 337 PHE B CE2 1 
ATOM   8306  C CZ  . PHE B 1 317 ? 136.518 100.287 63.900  1.00 45.20  ? 337 PHE B CZ  1 
ATOM   8307  N N   . ASP B 1 318 ? 135.223 94.990  64.608  1.00 53.32  ? 338 ASP B N   1 
ATOM   8308  C CA  . ASP B 1 318 ? 136.543 94.424  64.835  1.00 54.22  ? 338 ASP B CA  1 
ATOM   8309  C C   . ASP B 1 318 ? 136.890 93.454  63.710  1.00 55.46  ? 338 ASP B C   1 
ATOM   8310  O O   . ASP B 1 318 ? 138.002 93.482  63.200  1.00 56.64  ? 338 ASP B O   1 
ATOM   8311  C CB  . ASP B 1 318 ? 136.636 93.747  66.203  1.00 55.10  ? 338 ASP B CB  1 
ATOM   8312  C CG  . ASP B 1 318 ? 136.671 94.735  67.353  1.00 56.10  ? 338 ASP B CG  1 
ATOM   8313  O OD1 . ASP B 1 318 ? 137.120 95.873  67.127  1.00 55.69  ? 338 ASP B OD1 1 
ATOM   8314  O OD2 . ASP B 1 318 ? 136.213 94.375  68.453  1.00 57.14  ? 338 ASP B OD2 1 
ATOM   8315  N N   . ASP B 1 319 ? 135.933 92.609  63.318  1.00 57.00  ? 339 ASP B N   1 
ATOM   8316  C CA  . ASP B 1 319 ? 136.173 91.620  62.280  1.00 59.11  ? 339 ASP B CA  1 
ATOM   8317  C C   . ASP B 1 319 ? 136.565 92.310  60.974  1.00 58.18  ? 339 ASP B C   1 
ATOM   8318  O O   . ASP B 1 319 ? 137.447 91.829  60.266  1.00 58.15  ? 339 ASP B O   1 
ATOM   8319  C CB  . ASP B 1 319 ? 134.960 90.702  62.112  1.00 62.13  ? 339 ASP B CB  1 
ATOM   8320  C CG  . ASP B 1 319 ? 134.700 89.831  63.330  1.00 65.51  ? 339 ASP B CG  1 
ATOM   8321  O OD1 . ASP B 1 319 ? 135.493 89.917  64.293  1.00 66.54  ? 339 ASP B OD1 1 
ATOM   8322  O OD2 . ASP B 1 319 ? 133.707 89.075  63.309  1.00 67.51  ? 339 ASP B OD2 1 
ATOM   8323  N N   . TYR B 1 320 ? 135.913 93.435  60.660  1.00 57.56  ? 340 TYR B N   1 
ATOM   8324  C CA  . TYR B 1 320 ? 136.210 94.177  59.443  1.00 56.82  ? 340 TYR B CA  1 
ATOM   8325  C C   . TYR B 1 320 ? 137.556 94.893  59.561  1.00 55.63  ? 340 TYR B C   1 
ATOM   8326  O O   . TYR B 1 320 ? 138.328 94.921  58.605  1.00 56.32  ? 340 TYR B O   1 
ATOM   8327  C CB  . TYR B 1 320 ? 135.097 95.184  59.139  1.00 56.46  ? 340 TYR B CB  1 
ATOM   8328  C CG  . TYR B 1 320 ? 135.475 96.260  58.151  1.00 56.30  ? 340 TYR B CG  1 
ATOM   8329  C CD1 . TYR B 1 320 ? 135.724 95.961  56.821  1.00 57.30  ? 340 TYR B CD1 1 
ATOM   8330  C CD2 . TYR B 1 320 ? 135.607 97.580  58.549  1.00 56.37  ? 340 TYR B CD2 1 
ATOM   8331  C CE1 . TYR B 1 320 ? 136.081 96.945  55.911  1.00 58.38  ? 340 TYR B CE1 1 
ATOM   8332  C CE2 . TYR B 1 320 ? 135.978 98.575  57.657  1.00 57.04  ? 340 TYR B CE2 1 
ATOM   8333  C CZ  . TYR B 1 320 ? 136.205 98.259  56.329  1.00 58.20  ? 340 TYR B CZ  1 
ATOM   8334  O OH  . TYR B 1 320 ? 136.556 99.248  55.442  1.00 58.15  ? 340 TYR B OH  1 
ATOM   8335  N N   . TYR B 1 321 ? 137.823 95.470  60.738  1.00 53.55  ? 341 TYR B N   1 
ATOM   8336  C CA  . TYR B 1 321 ? 138.942 96.380  60.928  1.00 52.12  ? 341 TYR B CA  1 
ATOM   8337  C C   . TYR B 1 321 ? 140.271 95.622  60.945  1.00 52.83  ? 341 TYR B C   1 
ATOM   8338  O O   . TYR B 1 321 ? 141.243 96.056  60.333  1.00 54.10  ? 341 TYR B O   1 
ATOM   8339  C CB  . TYR B 1 321 ? 138.737 97.180  62.217  1.00 50.82  ? 341 TYR B CB  1 
ATOM   8340  C CG  . TYR B 1 321 ? 139.764 98.250  62.483  1.00 49.74  ? 341 TYR B CG  1 
ATOM   8341  C CD1 . TYR B 1 321 ? 139.854 99.373  61.676  1.00 49.62  ? 341 TYR B CD1 1 
ATOM   8342  C CD2 . TYR B 1 321 ? 140.639 98.149  63.552  1.00 49.42  ? 341 TYR B CD2 1 
ATOM   8343  C CE1 . TYR B 1 321 ? 140.788 100.366 61.923  1.00 49.40  ? 341 TYR B CE1 1 
ATOM   8344  C CE2 . TYR B 1 321 ? 141.580 99.130  63.813  1.00 49.44  ? 341 TYR B CE2 1 
ATOM   8345  C CZ  . TYR B 1 321 ? 141.656 100.242 62.993  1.00 49.34  ? 341 TYR B CZ  1 
ATOM   8346  O OH  . TYR B 1 321 ? 142.581 101.225 63.237  1.00 49.57  ? 341 TYR B OH  1 
ATOM   8347  N N   . LEU B 1 322 ? 140.307 94.480  61.638  1.00 53.71  ? 342 LEU B N   1 
ATOM   8348  C CA  . LEU B 1 322 ? 141.555 93.772  61.883  1.00 54.60  ? 342 LEU B CA  1 
ATOM   8349  C C   . LEU B 1 322 ? 142.124 93.172  60.597  1.00 56.83  ? 342 LEU B C   1 
ATOM   8350  O O   . LEU B 1 322 ? 143.294 92.799  60.574  1.00 57.94  ? 342 LEU B O   1 
ATOM   8351  C CB  . LEU B 1 322 ? 141.319 92.691  62.946  1.00 53.62  ? 342 LEU B CB  1 
ATOM   8352  C CG  . LEU B 1 322 ? 141.560 93.110  64.398  1.00 53.42  ? 342 LEU B CG  1 
ATOM   8353  C CD1 . LEU B 1 322 ? 140.847 94.406  64.743  1.00 52.29  ? 342 LEU B CD1 1 
ATOM   8354  C CD2 . LEU B 1 322 ? 141.118 92.010  65.350  1.00 55.09  ? 342 LEU B CD2 1 
ATOM   8355  N N   . LYS B 1 323 ? 141.319 93.091  59.531  1.00 59.68  ? 343 LYS B N   1 
ATOM   8356  C CA  . LYS B 1 323 ? 141.776 92.500  58.283  1.00 63.90  ? 343 LYS B CA  1 
ATOM   8357  C C   . LYS B 1 323 ? 142.257 93.570  57.303  1.00 65.57  ? 343 LYS B C   1 
ATOM   8358  O O   . LYS B 1 323 ? 142.646 93.235  56.185  1.00 66.19  ? 343 LYS B O   1 
ATOM   8359  C CB  . LYS B 1 323 ? 140.661 91.677  57.633  1.00 67.52  ? 343 LYS B CB  1 
ATOM   8360  C CG  . LYS B 1 323 ? 140.162 90.487  58.443  1.00 70.60  ? 343 LYS B CG  1 
ATOM   8361  C CD  . LYS B 1 323 ? 139.278 89.536  57.654  1.00 72.73  ? 343 LYS B CD  1 
ATOM   8362  C CE  . LYS B 1 323 ? 138.011 90.167  57.110  1.00 73.83  ? 343 LYS B CE  1 
ATOM   8363  N NZ  . LYS B 1 323 ? 137.079 90.587  58.183  1.00 73.98  ? 343 LYS B NZ  1 
ATOM   8364  N N   . LEU B 1 324 ? 142.237 94.844  57.715  1.00 67.71  ? 344 LEU B N   1 
ATOM   8365  C CA  . LEU B 1 324 ? 142.596 95.933  56.817  1.00 69.66  ? 344 LEU B CA  1 
ATOM   8366  C C   . LEU B 1 324 ? 144.102 95.945  56.572  1.00 73.22  ? 344 LEU B C   1 
ATOM   8367  O O   . LEU B 1 324 ? 144.893 95.779  57.497  1.00 73.51  ? 344 LEU B O   1 
ATOM   8368  C CB  . LEU B 1 324 ? 142.138 97.271  57.407  1.00 68.89  ? 344 LEU B CB  1 
ATOM   8369  C CG  . LEU B 1 324 ? 140.635 97.547  57.373  1.00 68.65  ? 344 LEU B CG  1 
ATOM   8370  C CD1 . LEU B 1 324 ? 140.347 98.978  57.797  1.00 67.69  ? 344 LEU B CD1 1 
ATOM   8371  C CD2 . LEU B 1 324 ? 140.039 97.259  56.001  1.00 69.76  ? 344 LEU B CD2 1 
ATOM   8372  N N   . ARG B 1 325 ? 144.475 96.163  55.307  1.00 78.69  ? 345 ARG B N   1 
ATOM   8373  C CA  . ARG B 1 325 ? 145.867 96.284  54.908  1.00 83.50  ? 345 ARG B CA  1 
ATOM   8374  C C   . ARG B 1 325 ? 146.045 97.611  54.176  1.00 84.69  ? 345 ARG B C   1 
ATOM   8375  O O   . ARG B 1 325 ? 145.133 98.065  53.488  1.00 85.27  ? 345 ARG B O   1 
ATOM   8376  C CB  . ARG B 1 325 ? 146.284 95.140  53.977  1.00 86.18  ? 345 ARG B CB  1 
ATOM   8377  C CG  . ARG B 1 325 ? 145.689 93.778  54.307  1.00 87.15  ? 345 ARG B CG  1 
ATOM   8378  C CD  . ARG B 1 325 ? 146.047 93.250  55.679  1.00 89.22  ? 345 ARG B CD  1 
ATOM   8379  N NE  . ARG B 1 325 ? 147.481 93.301  55.939  1.00 91.85  ? 345 ARG B NE  1 
ATOM   8380  C CZ  . ARG B 1 325 ? 148.074 92.824  57.029  1.00 94.35  ? 345 ARG B CZ  1 
ATOM   8381  N NH1 . ARG B 1 325 ? 147.373 92.165  57.937  1.00 94.41  ? 345 ARG B NH1 1 
ATOM   8382  N NH2 . ARG B 1 325 ? 149.377 92.989  57.193  1.00 94.04  ? 345 ARG B NH2 1 
ATOM   8383  N N   . PRO B 1 326 ? 147.225 98.263  54.273  1.00 85.88  ? 346 PRO B N   1 
ATOM   8384  C CA  . PRO B 1 326 ? 147.463 99.519  53.561  1.00 87.88  ? 346 PRO B CA  1 
ATOM   8385  C C   . PRO B 1 326 ? 147.446 99.393  52.036  1.00 91.57  ? 346 PRO B C   1 
ATOM   8386  O O   . PRO B 1 326 ? 147.193 100.373 51.344  1.00 92.29  ? 346 PRO B O   1 
ATOM   8387  C CB  . PRO B 1 326 ? 148.847 99.967  54.060  1.00 87.68  ? 346 PRO B CB  1 
ATOM   8388  C CG  . PRO B 1 326 ? 149.507 98.696  54.549  1.00 87.20  ? 346 PRO B CG  1 
ATOM   8389  C CD  . PRO B 1 326 ? 148.379 97.835  55.077  1.00 86.07  ? 346 PRO B CD  1 
ATOM   8390  N N   . GLU B 1 327 ? 147.694 98.186  51.515  1.00 96.53  ? 347 GLU B N   1 
ATOM   8391  C CA  . GLU B 1 327 ? 147.704 97.962  50.076  1.00 101.97 ? 347 GLU B CA  1 
ATOM   8392  C C   . GLU B 1 327 ? 146.280 97.962  49.521  1.00 102.99 ? 347 GLU B C   1 
ATOM   8393  O O   . GLU B 1 327 ? 146.039 98.535  48.462  1.00 103.48 ? 347 GLU B O   1 
ATOM   8394  C CB  . GLU B 1 327 ? 148.439 96.671  49.691  1.00 104.77 ? 347 GLU B CB  1 
ATOM   8395  C CG  . GLU B 1 327 ? 148.115 95.449  50.542  1.00 107.13 ? 347 GLU B CG  1 
ATOM   8396  C CD  . GLU B 1 327 ? 148.985 95.293  51.778  1.00 108.26 ? 347 GLU B CD  1 
ATOM   8397  O OE1 . GLU B 1 327 ? 149.320 96.330  52.377  1.00 107.53 ? 347 GLU B OE1 1 
ATOM   8398  O OE2 . GLU B 1 327 ? 149.305 94.141  52.150  1.00 108.93 ? 347 GLU B OE2 1 
ATOM   8399  N N   . THR B 1 328 ? 145.345 97.330  50.241  1.00 102.50 ? 348 THR B N   1 
ATOM   8400  C CA  . THR B 1 328 ? 144.007 97.074  49.727  1.00 103.19 ? 348 THR B CA  1 
ATOM   8401  C C   . THR B 1 328 ? 142.987 98.066  50.290  1.00 101.74 ? 348 THR B C   1 
ATOM   8402  O O   . THR B 1 328 ? 141.786 97.886  50.094  1.00 101.39 ? 348 THR B O   1 
ATOM   8403  C CB  . THR B 1 328 ? 143.585 95.630  50.033  1.00 104.46 ? 348 THR B CB  1 
ATOM   8404  O OG1 . THR B 1 328 ? 143.884 95.350  51.402  1.00 103.98 ? 348 THR B OG1 1 
ATOM   8405  C CG2 . THR B 1 328 ? 144.277 94.616  49.147  1.00 104.91 ? 348 THR B CG2 1 
ATOM   8406  N N   . ASN B 1 329 ? 143.462 99.122  50.966  1.00 99.60  ? 349 ASN B N   1 
ATOM   8407  C CA  . ASN B 1 329 ? 142.585 100.128 51.543  1.00 98.03  ? 349 ASN B CA  1 
ATOM   8408  C C   . ASN B 1 329 ? 142.976 101.493 50.984  1.00 98.38  ? 349 ASN B C   1 
ATOM   8409  O O   . ASN B 1 329 ? 143.870 102.149 51.514  1.00 97.99  ? 349 ASN B O   1 
ATOM   8410  C CB  . ASN B 1 329 ? 142.631 100.099 53.075  1.00 96.79  ? 349 ASN B CB  1 
ATOM   8411  C CG  . ASN B 1 329 ? 141.731 101.136 53.712  1.00 95.24  ? 349 ASN B CG  1 
ATOM   8412  O OD1 . ASN B 1 329 ? 142.088 102.307 53.780  1.00 93.42  ? 349 ASN B OD1 1 
ATOM   8413  N ND2 . ASN B 1 329 ? 140.576 100.720 54.206  1.00 94.49  ? 349 ASN B ND2 1 
ATOM   8414  N N   . LEU B 1 330 ? 142.290 101.912 49.911  1.00 100.34 ? 350 LEU B N   1 
ATOM   8415  C CA  . LEU B 1 330 ? 142.631 103.138 49.203  1.00 102.43 ? 350 LEU B CA  1 
ATOM   8416  C C   . LEU B 1 330 ? 141.640 104.257 49.526  1.00 99.19  ? 350 LEU B C   1 
ATOM   8417  O O   . LEU B 1 330 ? 141.991 105.431 49.426  1.00 99.21  ? 350 LEU B O   1 
ATOM   8418  C CB  . LEU B 1 330 ? 142.653 102.877 47.691  1.00 105.97 ? 350 LEU B CB  1 
ATOM   8419  C CG  . LEU B 1 330 ? 143.417 101.642 47.211  1.00 109.20 ? 350 LEU B CG  1 
ATOM   8420  C CD1 . LEU B 1 330 ? 142.475 100.463 47.023  1.00 109.52 ? 350 LEU B CD1 1 
ATOM   8421  C CD2 . LEU B 1 330 ? 144.173 101.922 45.915  1.00 110.88 ? 350 LEU B CD2 1 
ATOM   8422  N N   . ARG B 1 331 ? 140.406 103.892 49.907  1.00 93.34  ? 351 ARG B N   1 
ATOM   8423  C CA  . ARG B 1 331 ? 139.323 104.852 50.067  1.00 89.09  ? 351 ARG B CA  1 
ATOM   8424  C C   . ARG B 1 331 ? 139.529 105.715 51.313  1.00 82.86  ? 351 ARG B C   1 
ATOM   8425  O O   . ARG B 1 331 ? 138.885 106.755 51.449  1.00 82.69  ? 351 ARG B O   1 
ATOM   8426  C CB  . ARG B 1 331 ? 137.974 104.125 50.101  1.00 90.39  ? 351 ARG B CB  1 
ATOM   8427  C CG  . ARG B 1 331 ? 137.796 103.141 51.249  1.00 90.90  ? 351 ARG B CG  1 
ATOM   8428  C CD  . ARG B 1 331 ? 136.715 102.121 50.945  1.00 91.91  ? 351 ARG B CD  1 
ATOM   8429  N NE  . ARG B 1 331 ? 136.315 101.371 52.128  1.00 92.30  ? 351 ARG B NE  1 
ATOM   8430  C CZ  . ARG B 1 331 ? 135.076 100.955 52.385  1.00 92.14  ? 351 ARG B CZ  1 
ATOM   8431  N NH1 . ARG B 1 331 ? 134.123 101.111 51.482  1.00 91.97  ? 351 ARG B NH1 1 
ATOM   8432  N NH2 . ARG B 1 331 ? 134.794 100.362 53.533  1.00 91.98  ? 351 ARG B NH2 1 
ATOM   8433  N N   . ASN B 1 332 ? 140.414 105.278 52.218  1.00 75.42  ? 352 ASN B N   1 
ATOM   8434  C CA  . ASN B 1 332 ? 140.748 106.043 53.407  1.00 69.98  ? 352 ASN B CA  1 
ATOM   8435  C C   . ASN B 1 332 ? 142.065 106.773 53.155  1.00 67.55  ? 352 ASN B C   1 
ATOM   8436  O O   . ASN B 1 332 ? 143.117 106.146 53.057  1.00 68.62  ? 352 ASN B O   1 
ATOM   8437  C CB  . ASN B 1 332 ? 140.809 105.135 54.637  1.00 68.11  ? 352 ASN B CB  1 
ATOM   8438  C CG  . ASN B 1 332 ? 140.949 105.882 55.946  1.00 66.36  ? 352 ASN B CG  1 
ATOM   8439  O OD1 . ASN B 1 332 ? 141.387 107.029 55.975  1.00 66.54  ? 352 ASN B OD1 1 
ATOM   8440  N ND2 . ASN B 1 332 ? 140.604 105.225 57.041  1.00 64.38  ? 352 ASN B ND2 1 
ATOM   8441  N N   . PRO B 1 333 ? 142.058 108.119 53.038  1.00 65.98  ? 353 PRO B N   1 
ATOM   8442  C CA  . PRO B 1 333 ? 143.279 108.853 52.712  1.00 65.32  ? 353 PRO B CA  1 
ATOM   8443  C C   . PRO B 1 333 ? 144.288 108.921 53.858  1.00 63.14  ? 353 PRO B C   1 
ATOM   8444  O O   . PRO B 1 333 ? 145.458 109.211 53.621  1.00 64.03  ? 353 PRO B O   1 
ATOM   8445  C CB  . PRO B 1 333 ? 142.755 110.250 52.346  1.00 66.56  ? 353 PRO B CB  1 
ATOM   8446  C CG  . PRO B 1 333 ? 141.483 110.398 53.152  1.00 66.75  ? 353 PRO B CG  1 
ATOM   8447  C CD  . PRO B 1 333 ? 140.896 109.004 53.217  1.00 66.77  ? 353 PRO B CD  1 
ATOM   8448  N N   . TRP B 1 334 ? 143.840 108.638 55.089  1.00 59.73  ? 354 TRP B N   1 
ATOM   8449  C CA  . TRP B 1 334 ? 144.708 108.723 56.253  1.00 57.52  ? 354 TRP B CA  1 
ATOM   8450  C C   . TRP B 1 334 ? 145.213 107.351 56.693  1.00 57.84  ? 354 TRP B C   1 
ATOM   8451  O O   . TRP B 1 334 ? 145.888 107.257 57.715  1.00 58.31  ? 354 TRP B O   1 
ATOM   8452  C CB  . TRP B 1 334 ? 143.978 109.387 57.418  1.00 55.08  ? 354 TRP B CB  1 
ATOM   8453  C CG  . TRP B 1 334 ? 143.378 110.718 57.102  1.00 53.31  ? 354 TRP B CG  1 
ATOM   8454  C CD1 . TRP B 1 334 ? 144.012 111.922 57.002  1.00 53.40  ? 354 TRP B CD1 1 
ATOM   8455  C CD2 . TRP B 1 334 ? 141.990 110.973 56.850  1.00 51.88  ? 354 TRP B CD2 1 
ATOM   8456  N NE1 . TRP B 1 334 ? 143.110 112.909 56.708  1.00 53.30  ? 354 TRP B NE1 1 
ATOM   8457  C CE2 . TRP B 1 334 ? 141.860 112.355 56.611  1.00 52.31  ? 354 TRP B CE2 1 
ATOM   8458  C CE3 . TRP B 1 334 ? 140.851 110.164 56.799  1.00 51.35  ? 354 TRP B CE3 1 
ATOM   8459  C CZ2 . TRP B 1 334 ? 140.629 112.940 56.321  1.00 51.80  ? 354 TRP B CZ2 1 
ATOM   8460  C CZ3 . TRP B 1 334 ? 139.635 110.743 56.520  1.00 51.03  ? 354 TRP B CZ3 1 
ATOM   8461  C CH2 . TRP B 1 334 ? 139.528 112.114 56.290  1.00 51.29  ? 354 TRP B CH2 1 
ATOM   8462  N N   . PHE B 1 335 ? 144.883 106.288 55.952  1.00 58.57  ? 355 PHE B N   1 
ATOM   8463  C CA  . PHE B 1 335 ? 145.153 104.949 56.448  1.00 60.27  ? 355 PHE B CA  1 
ATOM   8464  C C   . PHE B 1 335 ? 146.647 104.634 56.385  1.00 63.04  ? 355 PHE B C   1 
ATOM   8465  O O   . PHE B 1 335 ? 147.172 103.963 57.273  1.00 64.30  ? 355 PHE B O   1 
ATOM   8466  C CB  . PHE B 1 335 ? 144.349 103.896 55.687  1.00 60.83  ? 355 PHE B CB  1 
ATOM   8467  C CG  . PHE B 1 335 ? 144.402 102.539 56.340  1.00 61.65  ? 355 PHE B CG  1 
ATOM   8468  C CD1 . PHE B 1 335 ? 143.839 102.333 57.590  1.00 61.21  ? 355 PHE B CD1 1 
ATOM   8469  C CD2 . PHE B 1 335 ? 145.057 101.484 55.728  1.00 62.92  ? 355 PHE B CD2 1 
ATOM   8470  C CE1 . PHE B 1 335 ? 143.905 101.091 58.200  1.00 61.37  ? 355 PHE B CE1 1 
ATOM   8471  C CE2 . PHE B 1 335 ? 145.123 100.242 56.340  1.00 62.81  ? 355 PHE B CE2 1 
ATOM   8472  C CZ  . PHE B 1 335 ? 144.550 100.048 57.576  1.00 62.56  ? 355 PHE B CZ  1 
ATOM   8473  N N   . GLN B 1 336 ? 147.328 105.120 55.340  1.00 64.43  ? 356 GLN B N   1 
ATOM   8474  C CA  . GLN B 1 336 ? 148.746 104.843 55.162  1.00 65.07  ? 356 GLN B CA  1 
ATOM   8475  C C   . GLN B 1 336 ? 149.558 105.581 56.224  1.00 61.64  ? 356 GLN B C   1 
ATOM   8476  O O   . GLN B 1 336 ? 150.492 105.017 56.790  1.00 61.23  ? 356 GLN B O   1 
ATOM   8477  C CB  . GLN B 1 336 ? 149.194 105.235 53.755  1.00 69.61  ? 356 GLN B CB  1 
ATOM   8478  C CG  . GLN B 1 336 ? 148.438 104.506 52.658  1.00 73.44  ? 356 GLN B CG  1 
ATOM   8479  C CD  . GLN B 1 336 ? 148.996 104.791 51.285  1.00 78.74  ? 356 GLN B CD  1 
ATOM   8480  O OE1 . GLN B 1 336 ? 150.059 105.393 51.119  1.00 81.54  ? 356 GLN B OE1 1 
ATOM   8481  N NE2 . GLN B 1 336 ? 148.281 104.332 50.272  1.00 81.05  ? 356 GLN B NE2 1 
ATOM   8482  N N   . GLU B 1 337 ? 149.193 106.842 56.484  1.00 59.94  ? 357 GLU B N   1 
ATOM   8483  C CA  . GLU B 1 337 ? 149.838 107.629 57.522  1.00 59.93  ? 357 GLU B CA  1 
ATOM   8484  C C   . GLU B 1 337 ? 149.652 106.941 58.871  1.00 56.33  ? 357 GLU B C   1 
ATOM   8485  O O   . GLU B 1 337 ? 150.578 106.899 59.677  1.00 57.93  ? 357 GLU B O   1 
ATOM   8486  C CB  . GLU B 1 337 ? 149.273 109.050 57.545  1.00 63.55  ? 357 GLU B CB  1 
ATOM   8487  C CG  . GLU B 1 337 ? 149.858 109.921 58.645  1.00 66.55  ? 357 GLU B CG  1 
ATOM   8488  C CD  . GLU B 1 337 ? 149.516 111.400 58.550  1.00 69.68  ? 357 GLU B CD  1 
ATOM   8489  O OE1 . GLU B 1 337 ? 148.811 111.791 57.594  1.00 70.15  ? 357 GLU B OE1 1 
ATOM   8490  O OE2 . GLU B 1 337 ? 149.961 112.161 59.433  1.00 71.32  ? 357 GLU B OE2 1 
ATOM   8491  N N   . PHE B 1 338 ? 148.447 106.410 59.105  1.00 52.24  ? 358 PHE B N   1 
ATOM   8492  C CA  . PHE B 1 338 ? 148.145 105.693 60.333  1.00 49.61  ? 358 PHE B CA  1 
ATOM   8493  C C   . PHE B 1 338 ? 149.001 104.435 60.440  1.00 51.27  ? 358 PHE B C   1 
ATOM   8494  O O   . PHE B 1 338 ? 149.485 104.111 61.522  1.00 52.68  ? 358 PHE B O   1 
ATOM   8495  C CB  . PHE B 1 338 ? 146.660 105.341 60.400  1.00 47.01  ? 358 PHE B CB  1 
ATOM   8496  C CG  . PHE B 1 338 ? 146.337 104.200 61.329  1.00 44.70  ? 358 PHE B CG  1 
ATOM   8497  C CD1 . PHE B 1 338 ? 146.465 104.341 62.701  1.00 43.66  ? 358 PHE B CD1 1 
ATOM   8498  C CD2 . PHE B 1 338 ? 145.929 102.975 60.825  1.00 44.32  ? 358 PHE B CD2 1 
ATOM   8499  C CE1 . PHE B 1 338 ? 146.172 103.285 63.550  1.00 43.29  ? 358 PHE B CE1 1 
ATOM   8500  C CE2 . PHE B 1 338 ? 145.636 101.921 61.676  1.00 44.19  ? 358 PHE B CE2 1 
ATOM   8501  C CZ  . PHE B 1 338 ? 145.756 102.079 63.036  1.00 43.58  ? 358 PHE B CZ  1 
ATOM   8502  N N   . TRP B 1 339 ? 149.169 103.732 59.315  1.00 52.96  ? 359 TRP B N   1 
ATOM   8503  C CA  . TRP B 1 339 ? 149.953 102.509 59.288  1.00 54.93  ? 359 TRP B CA  1 
ATOM   8504  C C   . TRP B 1 339 ? 151.398 102.803 59.682  1.00 56.30  ? 359 TRP B C   1 
ATOM   8505  O O   . TRP B 1 339 ? 152.003 102.051 60.443  1.00 57.82  ? 359 TRP B O   1 
ATOM   8506  C CB  . TRP B 1 339 ? 149.886 101.852 57.908  1.00 56.15  ? 359 TRP B CB  1 
ATOM   8507  C CG  . TRP B 1 339 ? 150.296 100.412 57.905  1.00 57.18  ? 359 TRP B CG  1 
ATOM   8508  C CD1 . TRP B 1 339 ? 151.521 99.898  57.595  1.00 58.65  ? 359 TRP B CD1 1 
ATOM   8509  C CD2 . TRP B 1 339 ? 149.453 99.288  58.203  1.00 58.70  ? 359 TRP B CD2 1 
ATOM   8510  N NE1 . TRP B 1 339 ? 151.501 98.532  57.689  1.00 59.60  ? 359 TRP B NE1 1 
ATOM   8511  C CE2 . TRP B 1 339 ? 150.244 98.129  58.057  1.00 59.92  ? 359 TRP B CE2 1 
ATOM   8512  C CE3 . TRP B 1 339 ? 148.112 99.150  58.578  1.00 60.34  ? 359 TRP B CE3 1 
ATOM   8513  C CZ2 . TRP B 1 339 ? 149.732 96.849  58.272  1.00 61.35  ? 359 TRP B CZ2 1 
ATOM   8514  C CZ3 . TRP B 1 339 ? 147.608 97.887  58.794  1.00 61.35  ? 359 TRP B CZ3 1 
ATOM   8515  C CH2 . TRP B 1 339 ? 148.409 96.755  58.641  1.00 61.50  ? 359 TRP B CH2 1 
ATOM   8516  N N   . GLN B 1 340 ? 151.948 103.900 59.150  1.00 57.88  ? 360 GLN B N   1 
ATOM   8517  C CA  . GLN B 1 340 ? 153.320 104.274 59.444  1.00 59.61  ? 360 GLN B CA  1 
ATOM   8518  C C   . GLN B 1 340 ? 153.448 104.688 60.905  1.00 58.24  ? 360 GLN B C   1 
ATOM   8519  O O   . GLN B 1 340 ? 154.404 104.301 61.570  1.00 60.24  ? 360 GLN B O   1 
ATOM   8520  C CB  . GLN B 1 340 ? 153.793 105.397 58.525  1.00 62.70  ? 360 GLN B CB  1 
ATOM   8521  C CG  . GLN B 1 340 ? 153.615 105.059 57.055  1.00 65.86  ? 360 GLN B CG  1 
ATOM   8522  C CD  . GLN B 1 340 ? 154.787 105.481 56.207  1.00 71.10  ? 360 GLN B CD  1 
ATOM   8523  O OE1 . GLN B 1 340 ? 155.837 105.862 56.718  1.00 75.26  ? 360 GLN B OE1 1 
ATOM   8524  N NE2 . GLN B 1 340 ? 154.621 105.384 54.898  1.00 73.93  ? 360 GLN B NE2 1 
ATOM   8525  N N   . HIS B 1 341 ? 152.490 105.475 61.402  1.00 57.55  ? 361 HIS B N   1 
ATOM   8526  C CA  . HIS B 1 341 ? 152.585 106.003 62.752  1.00 58.26  ? 361 HIS B CA  1 
ATOM   8527  C C   . HIS B 1 341 ? 152.463 104.876 63.772  1.00 59.85  ? 361 HIS B C   1 
ATOM   8528  O O   . HIS B 1 341 ? 153.200 104.854 64.755  1.00 61.77  ? 361 HIS B O   1 
ATOM   8529  C CB  . HIS B 1 341 ? 151.533 107.085 63.004  1.00 58.64  ? 361 HIS B CB  1 
ATOM   8530  C CG  . HIS B 1 341 ? 151.556 107.592 64.403  1.00 59.37  ? 361 HIS B CG  1 
ATOM   8531  N ND1 . HIS B 1 341 ? 152.601 108.331 64.914  1.00 60.38  ? 361 HIS B ND1 1 
ATOM   8532  C CD2 . HIS B 1 341 ? 150.673 107.455 65.398  1.00 60.54  ? 361 HIS B CD2 1 
ATOM   8533  C CE1 . HIS B 1 341 ? 152.341 108.632 66.178  1.00 61.74  ? 361 HIS B CE1 1 
ATOM   8534  N NE2 . HIS B 1 341 ? 151.174 108.111 66.492  1.00 61.48  ? 361 HIS B NE2 1 
ATOM   8535  N N   . ARG B 1 342 ? 151.526 103.953 63.531  1.00 61.48  ? 362 ARG B N   1 
ATOM   8536  C CA  . ARG B 1 342 ? 151.245 102.875 64.465  1.00 63.62  ? 362 ARG B CA  1 
ATOM   8537  C C   . ARG B 1 342 ? 152.448 101.939 64.549  1.00 65.97  ? 362 ARG B C   1 
ATOM   8538  O O   . ARG B 1 342 ? 153.084 101.841 65.598  1.00 66.97  ? 362 ARG B O   1 
ATOM   8539  C CB  . ARG B 1 342 ? 149.972 102.130 64.055  1.00 63.50  ? 362 ARG B CB  1 
ATOM   8540  C CG  . ARG B 1 342 ? 149.668 100.921 64.927  1.00 63.51  ? 362 ARG B CG  1 
ATOM   8541  C CD  . ARG B 1 342 ? 148.221 100.498 64.802  1.00 63.71  ? 362 ARG B CD  1 
ATOM   8542  N NE  . ARG B 1 342 ? 147.957 99.217  65.438  1.00 64.32  ? 362 ARG B NE  1 
ATOM   8543  C CZ  . ARG B 1 342 ? 147.965 98.997  66.747  1.00 65.51  ? 362 ARG B CZ  1 
ATOM   8544  N NH1 . ARG B 1 342 ? 148.175 99.983  67.602  1.00 65.37  ? 362 ARG B NH1 1 
ATOM   8545  N NH2 . ARG B 1 342 ? 147.740 97.777  67.205  1.00 66.73  ? 362 ARG B NH2 1 
ATOM   8546  N N   . PHE B 1 343 ? 152.745 101.255 63.439  1.00 68.13  ? 363 PHE B N   1 
ATOM   8547  C CA  . PHE B 1 343 ? 153.961 100.468 63.330  1.00 71.17  ? 363 PHE B CA  1 
ATOM   8548  C C   . PHE B 1 343 ? 155.050 101.364 62.749  1.00 75.61  ? 363 PHE B C   1 
ATOM   8549  O O   . PHE B 1 343 ? 155.032 101.652 61.555  1.00 77.97  ? 363 PHE B O   1 
ATOM   8550  C CB  . PHE B 1 343 ? 153.741 99.241  62.444  1.00 71.46  ? 363 PHE B CB  1 
ATOM   8551  C CG  . PHE B 1 343 ? 152.437 98.522  62.669  1.00 72.65  ? 363 PHE B CG  1 
ATOM   8552  C CD1 . PHE B 1 343 ? 152.143 97.950  63.896  1.00 74.62  ? 363 PHE B CD1 1 
ATOM   8553  C CD2 . PHE B 1 343 ? 151.508 98.407  61.646  1.00 72.81  ? 363 PHE B CD2 1 
ATOM   8554  C CE1 . PHE B 1 343 ? 150.948 97.274  64.094  1.00 75.14  ? 363 PHE B CE1 1 
ATOM   8555  C CE2 . PHE B 1 343 ? 150.310 97.739  61.848  1.00 73.54  ? 363 PHE B CE2 1 
ATOM   8556  C CZ  . PHE B 1 343 ? 150.033 97.173  63.070  1.00 74.52  ? 363 PHE B CZ  1 
ATOM   8557  N N   . GLN B 1 344 ? 155.975 101.819 63.603  1.00 79.34  ? 364 GLN B N   1 
ATOM   8558  C CA  . GLN B 1 344 ? 157.007 102.757 63.189  1.00 84.03  ? 364 GLN B CA  1 
ATOM   8559  C C   . GLN B 1 344 ? 157.795 102.142 62.036  1.00 86.79  ? 364 GLN B C   1 
ATOM   8560  O O   . GLN B 1 344 ? 158.598 101.240 62.258  1.00 89.15  ? 364 GLN B O   1 
ATOM   8561  C CB  . GLN B 1 344 ? 157.948 103.087 64.352  1.00 86.77  ? 364 GLN B CB  1 
ATOM   8562  C CG  . GLN B 1 344 ? 157.252 103.506 65.642  1.00 88.81  ? 364 GLN B CG  1 
ATOM   8563  C CD  . GLN B 1 344 ? 156.563 104.846 65.558  1.00 91.77  ? 364 GLN B CD  1 
ATOM   8564  O OE1 . GLN B 1 344 ? 156.660 105.568 64.569  1.00 91.94  ? 364 GLN B OE1 1 
ATOM   8565  N NE2 . GLN B 1 344 ? 155.868 105.205 66.626  1.00 93.47  ? 364 GLN B NE2 1 
ATOM   8566  N N   . CYS B 1 345 ? 157.553 102.633 60.812  1.00 89.74  ? 365 CYS B N   1 
ATOM   8567  C CA  . CYS B 1 345 ? 158.124 102.050 59.604  1.00 94.67  ? 365 CYS B CA  1 
ATOM   8568  C C   . CYS B 1 345 ? 157.752 102.916 58.403  1.00 97.86  ? 365 CYS B C   1 
ATOM   8569  O O   . CYS B 1 345 ? 157.081 103.928 58.565  1.00 96.92  ? 365 CYS B O   1 
ATOM   8570  C CB  . CYS B 1 345 ? 157.650 100.618 59.373  1.00 97.14  ? 365 CYS B CB  1 
ATOM   8571  S SG  . CYS B 1 345 ? 155.866 100.469 59.107  1.00 101.39 ? 365 CYS B SG  1 
ATOM   8572  N N   . ARG B 1 346 ? 158.213 102.533 57.208  1.00 104.53 ? 366 ARG B N   1 
ATOM   8573  C CA  . ARG B 1 346 ? 157.962 103.277 55.981  1.00 111.33 ? 366 ARG B CA  1 
ATOM   8574  C C   . ARG B 1 346 ? 157.569 102.301 54.876  1.00 114.66 ? 366 ARG B C   1 
ATOM   8575  O O   . ARG B 1 346 ? 158.179 101.246 54.733  1.00 115.78 ? 366 ARG B O   1 
ATOM   8576  C CB  . ARG B 1 346 ? 159.217 104.066 55.584  1.00 117.26 ? 366 ARG B CB  1 
ATOM   8577  C CG  . ARG B 1 346 ? 159.306 104.445 54.110  1.00 122.34 ? 366 ARG B CG  1 
ATOM   8578  C CD  . ARG B 1 346 ? 160.721 104.775 53.690  1.00 125.57 ? 366 ARG B CD  1 
ATOM   8579  N NE  . ARG B 1 346 ? 161.644 103.679 53.957  1.00 127.62 ? 366 ARG B NE  1 
ATOM   8580  C CZ  . ARG B 1 346 ? 162.594 103.678 54.889  1.00 128.13 ? 366 ARG B CZ  1 
ATOM   8581  N NH1 . ARG B 1 346 ? 162.747 104.712 55.698  1.00 127.84 ? 366 ARG B NH1 1 
ATOM   8582  N NH2 . ARG B 1 346 ? 163.383 102.624 55.022  1.00 127.44 ? 366 ARG B NH2 1 
ATOM   8583  N N   . LEU B 1 347 ? 156.548 102.667 54.095  1.00 121.14 ? 367 LEU B N   1 
ATOM   8584  C CA  . LEU B 1 347 ? 156.143 101.893 52.933  1.00 129.60 ? 367 LEU B CA  1 
ATOM   8585  C C   . LEU B 1 347 ? 156.793 102.496 51.689  1.00 140.36 ? 367 LEU B C   1 
ATOM   8586  O O   . LEU B 1 347 ? 156.438 103.599 51.276  1.00 143.41 ? 367 LEU B O   1 
ATOM   8587  C CB  . LEU B 1 347 ? 154.615 101.904 52.809  1.00 128.11 ? 367 LEU B CB  1 
ATOM   8588  C CG  . LEU B 1 347 ? 153.834 101.203 53.923  1.00 125.25 ? 367 LEU B CG  1 
ATOM   8589  C CD1 . LEU B 1 347 ? 153.367 102.200 54.973  1.00 122.61 ? 367 LEU B CD1 1 
ATOM   8590  C CD2 . LEU B 1 347 ? 152.651 100.421 53.373  1.00 124.92 ? 367 LEU B CD2 1 
ATOM   8591  N N   . GLU B 1 348 ? 157.749 101.763 51.100  1.00 149.42 ? 368 GLU B N   1 
ATOM   8592  C CA  . GLU B 1 348 ? 158.457 102.228 49.915  1.00 158.13 ? 368 GLU B CA  1 
ATOM   8593  C C   . GLU B 1 348 ? 157.556 102.175 48.679  1.00 163.91 ? 368 GLU B C   1 
ATOM   8594  O O   . GLU B 1 348 ? 157.795 102.902 47.716  1.00 164.69 ? 368 GLU B O   1 
ATOM   8595  C CB  . GLU B 1 348 ? 159.723 101.403 49.661  1.00 161.42 ? 368 GLU B CB  1 
ATOM   8596  C CG  . GLU B 1 348 ? 160.866 101.720 50.610  1.00 163.50 ? 368 GLU B CG  1 
ATOM   8597  C CD  . GLU B 1 348 ? 160.709 101.198 52.028  1.00 164.07 ? 368 GLU B CD  1 
ATOM   8598  O OE1 . GLU B 1 348 ? 159.730 100.473 52.287  1.00 164.83 ? 368 GLU B OE1 1 
ATOM   8599  O OE2 . GLU B 1 348 ? 161.572 101.522 52.872  1.00 161.98 ? 368 GLU B OE2 1 
ATOM   8600  N N   . GLY B 1 349 ? 156.528 101.317 48.707  1.00 170.69 ? 369 GLY B N   1 
ATOM   8601  C CA  . GLY B 1 349 ? 155.734 101.030 47.523  1.00 178.07 ? 369 GLY B CA  1 
ATOM   8602  C C   . GLY B 1 349 ? 154.569 101.998 47.315  1.00 185.72 ? 369 GLY B C   1 
ATOM   8603  O O   . GLY B 1 349 ? 153.727 101.756 46.452  1.00 186.09 ? 369 GLY B O   1 
ATOM   8604  N N   . PHE B 1 350 ? 154.518 103.083 48.101  1.00 191.89 ? 370 PHE B N   1 
ATOM   8605  C CA  . PHE B 1 350 ? 153.435 104.050 47.999  1.00 195.41 ? 370 PHE B CA  1 
ATOM   8606  C C   . PHE B 1 350 ? 154.005 105.461 47.867  1.00 198.09 ? 370 PHE B C   1 
ATOM   8607  O O   . PHE B 1 350 ? 155.108 105.734 48.341  1.00 196.22 ? 370 PHE B O   1 
ATOM   8608  C CB  . PHE B 1 350 ? 152.499 103.956 49.208  1.00 194.38 ? 370 PHE B CB  1 
ATOM   8609  C CG  . PHE B 1 350 ? 151.782 102.636 49.341  1.00 194.56 ? 370 PHE B CG  1 
ATOM   8610  C CD1 . PHE B 1 350 ? 152.431 101.522 49.850  1.00 194.41 ? 370 PHE B CD1 1 
ATOM   8611  C CD2 . PHE B 1 350 ? 150.463 102.502 48.934  1.00 195.11 ? 370 PHE B CD2 1 
ATOM   8612  C CE1 . PHE B 1 350 ? 151.773 100.306 49.961  1.00 195.73 ? 370 PHE B CE1 1 
ATOM   8613  C CE2 . PHE B 1 350 ? 149.804 101.286 49.052  1.00 196.79 ? 370 PHE B CE2 1 
ATOM   8614  C CZ  . PHE B 1 350 ? 150.459 100.193 49.572  1.00 196.00 ? 370 PHE B CZ  1 
ATOM   8615  N N   . PRO B 1 351 ? 153.261 106.405 47.240  1.00 200.33 ? 371 PRO B N   1 
ATOM   8616  C CA  . PRO B 1 351 ? 153.688 107.803 47.153  1.00 200.13 ? 371 PRO B CA  1 
ATOM   8617  C C   . PRO B 1 351 ? 153.979 108.444 48.510  1.00 197.82 ? 371 PRO B C   1 
ATOM   8618  O O   . PRO B 1 351 ? 154.898 109.251 48.622  1.00 197.02 ? 371 PRO B O   1 
ATOM   8619  C CB  . PRO B 1 351 ? 152.507 108.508 46.463  1.00 200.43 ? 371 PRO B CB  1 
ATOM   8620  C CG  . PRO B 1 351 ? 151.806 107.405 45.701  1.00 200.78 ? 371 PRO B CG  1 
ATOM   8621  C CD  . PRO B 1 351 ? 151.969 106.178 46.571  1.00 200.65 ? 371 PRO B CD  1 
ATOM   8622  N N   . GLN B 1 352 ? 153.201 108.073 49.538  1.00 194.55 ? 372 GLN B N   1 
ATOM   8623  C CA  . GLN B 1 352 ? 153.408 108.567 50.890  1.00 192.12 ? 372 GLN B CA  1 
ATOM   8624  C C   . GLN B 1 352 ? 154.459 107.709 51.596  1.00 184.98 ? 372 GLN B C   1 
ATOM   8625  O O   . GLN B 1 352 ? 154.131 106.912 52.473  1.00 180.81 ? 372 GLN B O   1 
ATOM   8626  C CB  . GLN B 1 352 ? 152.083 108.563 51.657  1.00 193.87 ? 372 GLN B CB  1 
ATOM   8627  C CG  . GLN B 1 352 ? 151.061 109.575 51.147  1.00 195.38 ? 372 GLN B CG  1 
ATOM   8628  C CD  . GLN B 1 352 ? 150.261 109.129 49.945  1.00 196.97 ? 372 GLN B CD  1 
ATOM   8629  O OE1 . GLN B 1 352 ? 150.585 108.155 49.268  1.00 197.01 ? 372 GLN B OE1 1 
ATOM   8630  N NE2 . GLN B 1 352 ? 149.206 109.871 49.651  1.00 197.73 ? 372 GLN B NE2 1 
ATOM   8631  N N   . GLU B 1 353 ? 155.726 107.884 51.202  1.00 182.18 ? 373 GLU B N   1 
ATOM   8632  C CA  . GLU B 1 353 ? 156.824 107.119 51.770  1.00 181.18 ? 373 GLU B CA  1 
ATOM   8633  C C   . GLU B 1 353 ? 157.012 107.499 53.235  1.00 177.69 ? 373 GLU B C   1 
ATOM   8634  O O   . GLU B 1 353 ? 157.102 106.625 54.093  1.00 175.96 ? 373 GLU B O   1 
ATOM   8635  C CB  . GLU B 1 353 ? 158.116 107.346 50.981  1.00 183.27 ? 373 GLU B CB  1 
ATOM   8636  C CG  . GLU B 1 353 ? 158.068 106.799 49.565  1.00 183.77 ? 373 GLU B CG  1 
ATOM   8637  C CD  . GLU B 1 353 ? 159.326 107.044 48.747  1.00 184.20 ? 373 GLU B CD  1 
ATOM   8638  O OE1 . GLU B 1 353 ? 160.325 107.522 49.323  1.00 183.41 ? 373 GLU B OE1 1 
ATOM   8639  O OE2 . GLU B 1 353 ? 159.302 106.767 47.531  1.00 184.64 ? 373 GLU B OE2 1 
ATOM   8640  N N   . ASN B 1 354 ? 157.068 108.808 53.507  1.00 174.90 ? 374 ASN B N   1 
ATOM   8641  C CA  . ASN B 1 354 ? 157.316 109.327 54.845  1.00 171.79 ? 374 ASN B CA  1 
ATOM   8642  C C   . ASN B 1 354 ? 158.653 108.784 55.355  1.00 169.83 ? 374 ASN B C   1 
ATOM   8643  O O   . ASN B 1 354 ? 158.706 107.995 56.301  1.00 166.38 ? 374 ASN B O   1 
ATOM   8644  C CB  . ASN B 1 354 ? 156.142 109.027 55.783  1.00 169.01 ? 374 ASN B CB  1 
ATOM   8645  C CG  . ASN B 1 354 ? 156.122 109.903 57.020  1.00 167.74 ? 374 ASN B CG  1 
ATOM   8646  O OD1 . ASN B 1 354 ? 157.039 110.689 57.251  1.00 166.39 ? 374 ASN B OD1 1 
ATOM   8647  N ND2 . ASN B 1 354 ? 155.075 109.781 57.821  1.00 167.40 ? 374 ASN B ND2 1 
ATOM   8648  N N   . SER B 1 355 ? 159.739 109.256 54.730  1.00 168.05 ? 375 SER B N   1 
ATOM   8649  C CA  . SER B 1 355 ? 161.073 108.715 54.942  1.00 166.18 ? 375 SER B CA  1 
ATOM   8650  C C   . SER B 1 355 ? 161.641 109.084 56.315  1.00 161.13 ? 375 SER B C   1 
ATOM   8651  O O   . SER B 1 355 ? 162.811 108.815 56.582  1.00 161.35 ? 375 SER B O   1 
ATOM   8652  C CB  . SER B 1 355 ? 161.999 109.167 53.839  1.00 167.91 ? 375 SER B CB  1 
ATOM   8653  O OG  . SER B 1 355 ? 162.103 110.584 53.816  1.00 167.55 ? 375 SER B OG  1 
ATOM   8654  N N   . LYS B 1 356 ? 160.824 109.691 57.187  1.00 153.87 ? 376 LYS B N   1 
ATOM   8655  C CA  . LYS B 1 356 ? 161.280 110.056 58.519  1.00 148.50 ? 376 LYS B CA  1 
ATOM   8656  C C   . LYS B 1 356 ? 161.570 108.788 59.322  1.00 142.96 ? 376 LYS B C   1 
ATOM   8657  O O   . LYS B 1 356 ? 162.510 108.761 60.108  1.00 141.18 ? 376 LYS B O   1 
ATOM   8658  C CB  . LYS B 1 356 ? 160.264 110.968 59.220  1.00 147.34 ? 376 LYS B CB  1 
ATOM   8659  C CG  . LYS B 1 356 ? 159.429 110.337 60.327  1.00 146.53 ? 376 LYS B CG  1 
ATOM   8660  C CD  . LYS B 1 356 ? 158.550 111.347 61.035  1.00 146.91 ? 376 LYS B CD  1 
ATOM   8661  C CE  . LYS B 1 356 ? 157.723 110.745 62.149  1.00 147.45 ? 376 LYS B CE  1 
ATOM   8662  N NZ  . LYS B 1 356 ? 156.733 111.710 62.683  1.00 147.74 ? 376 LYS B NZ  1 
ATOM   8663  N N   . TYR B 1 357 ? 160.748 107.751 59.132  1.00 137.97 ? 377 TYR B N   1 
ATOM   8664  C CA  . TYR B 1 357 ? 160.935 106.487 59.827  1.00 135.32 ? 377 TYR B CA  1 
ATOM   8665  C C   . TYR B 1 357 ? 162.137 105.749 59.242  1.00 134.86 ? 377 TYR B C   1 
ATOM   8666  O O   . TYR B 1 357 ? 162.350 105.761 58.033  1.00 132.55 ? 377 TYR B O   1 
ATOM   8667  C CB  . TYR B 1 357 ? 159.662 105.646 59.736  1.00 133.96 ? 377 TYR B CB  1 
ATOM   8668  C CG  . TYR B 1 357 ? 158.436 106.353 60.246  1.00 132.02 ? 377 TYR B CG  1 
ATOM   8669  C CD1 . TYR B 1 357 ? 158.217 106.519 61.603  1.00 130.24 ? 377 TYR B CD1 1 
ATOM   8670  C CD2 . TYR B 1 357 ? 157.509 106.888 59.367  1.00 131.76 ? 377 TYR B CD2 1 
ATOM   8671  C CE1 . TYR B 1 357 ? 157.098 107.186 62.075  1.00 130.08 ? 377 TYR B CE1 1 
ATOM   8672  C CE2 . TYR B 1 357 ? 156.384 107.556 59.823  1.00 130.71 ? 377 TYR B CE2 1 
ATOM   8673  C CZ  . TYR B 1 357 ? 156.179 107.708 61.182  1.00 130.58 ? 377 TYR B CZ  1 
ATOM   8674  O OH  . TYR B 1 357 ? 155.061 108.361 61.638  1.00 129.56 ? 377 TYR B OH  1 
ATOM   8675  N N   . ASN B 1 358 ? 162.902 105.096 60.121  1.00 135.39 ? 378 ASN B N   1 
ATOM   8676  C CA  . ASN B 1 358 ? 164.154 104.456 59.748  1.00 135.18 ? 378 ASN B CA  1 
ATOM   8677  C C   . ASN B 1 358 ? 163.873 103.126 59.051  1.00 131.50 ? 378 ASN B C   1 
ATOM   8678  O O   . ASN B 1 358 ? 164.296 102.911 57.916  1.00 131.54 ? 378 ASN B O   1 
ATOM   8679  C CB  . ASN B 1 358 ? 165.071 104.274 60.962  1.00 137.00 ? 378 ASN B CB  1 
ATOM   8680  C CG  . ASN B 1 358 ? 164.330 103.819 62.203  1.00 137.70 ? 378 ASN B CG  1 
ATOM   8681  O OD1 . ASN B 1 358 ? 163.560 102.861 62.155  1.00 136.67 ? 378 ASN B OD1 1 
ATOM   8682  N ND2 . ASN B 1 358 ? 164.531 104.512 63.313  1.00 136.96 ? 378 ASN B ND2 1 
ATOM   8683  N N   . LYS B 1 359 ? 163.149 102.234 59.736  1.00 126.66 ? 379 LYS B N   1 
ATOM   8684  C CA  . LYS B 1 359 ? 162.982 100.867 59.264  1.00 123.95 ? 379 LYS B CA  1 
ATOM   8685  C C   . LYS B 1 359 ? 161.862 100.816 58.227  1.00 120.66 ? 379 LYS B C   1 
ATOM   8686  O O   . LYS B 1 359 ? 161.158 101.799 58.015  1.00 120.84 ? 379 LYS B O   1 
ATOM   8687  C CB  . LYS B 1 359 ? 162.700 99.923  60.438  1.00 124.47 ? 379 LYS B CB  1 
ATOM   8688  C CG  . LYS B 1 359 ? 161.386 100.163 61.168  1.00 126.16 ? 379 LYS B CG  1 
ATOM   8689  C CD  . LYS B 1 359 ? 160.988 99.032  62.100  1.00 126.82 ? 379 LYS B CD  1 
ATOM   8690  C CE  . LYS B 1 359 ? 161.572 99.157  63.491  1.00 127.12 ? 379 LYS B CE  1 
ATOM   8691  N NZ  . LYS B 1 359 ? 160.901 100.220 64.276  1.00 126.66 ? 379 LYS B NZ  1 
ATOM   8692  N N   . THR B 1 360 ? 161.697 99.640  57.609  1.00 118.59 ? 380 THR B N   1 
ATOM   8693  C CA  . THR B 1 360 ? 160.636 99.377  56.648  1.00 118.73 ? 380 THR B CA  1 
ATOM   8694  C C   . THR B 1 360 ? 159.642 98.376  57.233  1.00 118.59 ? 380 THR B C   1 
ATOM   8695  O O   . THR B 1 360 ? 160.014 97.574  58.085  1.00 120.71 ? 380 THR B O   1 
ATOM   8696  C CB  . THR B 1 360 ? 161.220 98.857  55.329  1.00 119.92 ? 380 THR B CB  1 
ATOM   8697  O OG1 . THR B 1 360 ? 160.146 98.745  54.393  1.00 119.65 ? 380 THR B OG1 1 
ATOM   8698  C CG2 . THR B 1 360 ? 161.920 97.520  55.457  1.00 120.36 ? 380 THR B CG2 1 
ATOM   8699  N N   . CYS B 1 361 ? 158.389 98.389  56.746  1.00 116.76 ? 381 CYS B N   1 
ATOM   8700  C CA  . CYS B 1 361 ? 157.383 97.450  57.234  1.00 116.10 ? 381 CYS B CA  1 
ATOM   8701  C C   . CYS B 1 361 ? 157.388 96.174  56.388  1.00 117.46 ? 381 CYS B C   1 
ATOM   8702  O O   . CYS B 1 361 ? 157.165 96.220  55.177  1.00 116.86 ? 381 CYS B O   1 
ATOM   8703  C CB  . CYS B 1 361 ? 155.944 97.972  57.224  1.00 113.76 ? 381 CYS B CB  1 
ATOM   8704  S SG  . CYS B 1 361 ? 155.691 99.769  57.201  1.00 110.88 ? 381 CYS B SG  1 
ATOM   8705  N N   . ASN B 1 362 ? 157.643 95.040  57.048  1.00 118.73 ? 382 ASN B N   1 
ATOM   8706  C CA  . ASN B 1 362 ? 157.502 93.728  56.438  1.00 119.97 ? 382 ASN B CA  1 
ATOM   8707  C C   . ASN B 1 362 ? 156.020 93.370  56.360  1.00 118.65 ? 382 ASN B C   1 
ATOM   8708  O O   . ASN B 1 362 ? 155.205 93.886  57.123  1.00 118.53 ? 382 ASN B O   1 
ATOM   8709  C CB  . ASN B 1 362 ? 158.293 92.666  57.204  1.00 121.40 ? 382 ASN B CB  1 
ATOM   8710  C CG  . ASN B 1 362 ? 158.081 92.739  58.702  1.00 120.60 ? 382 ASN B CG  1 
ATOM   8711  O OD1 . ASN B 1 362 ? 157.388 93.627  59.197  1.00 119.22 ? 382 ASN B OD1 1 
ATOM   8712  N ND2 . ASN B 1 362 ? 158.689 91.822  59.435  1.00 119.44 ? 382 ASN B ND2 1 
ATOM   8713  N N   . SER B 1 363 ? 155.685 92.442  55.458  1.00 118.19 ? 383 SER B N   1 
ATOM   8714  C CA  . SER B 1 363 ? 154.302 92.053  55.233  1.00 117.46 ? 383 SER B CA  1 
ATOM   8715  C C   . SER B 1 363 ? 153.864 91.016  56.268  1.00 113.54 ? 383 SER B C   1 
ATOM   8716  O O   . SER B 1 363 ? 153.300 89.983  55.913  1.00 114.39 ? 383 SER B O   1 
ATOM   8717  C CB  . SER B 1 363 ? 154.114 91.547  53.822  1.00 119.62 ? 383 SER B CB  1 
ATOM   8718  O OG  . SER B 1 363 ? 154.949 90.426  53.569  1.00 121.15 ? 383 SER B OG  1 
ATOM   8719  N N   . SER B 1 364 ? 154.120 91.304  57.551  1.00 109.33 ? 384 SER B N   1 
ATOM   8720  C CA  . SER B 1 364 ? 153.732 90.413  58.633  1.00 107.80 ? 384 SER B CA  1 
ATOM   8721  C C   . SER B 1 364 ? 153.222 91.198  59.842  1.00 103.56 ? 384 SER B C   1 
ATOM   8722  O O   . SER B 1 364 ? 153.097 90.640  60.931  1.00 103.43 ? 384 SER B O   1 
ATOM   8723  C CB  . SER B 1 364 ? 154.879 89.510  59.014  1.00 110.18 ? 384 SER B CB  1 
ATOM   8724  O OG  . SER B 1 364 ? 155.971 90.262  59.522  1.00 111.08 ? 384 SER B OG  1 
ATOM   8725  N N   . LEU B 1 365 ? 152.903 92.483  59.642  1.00 98.18  ? 385 LEU B N   1 
ATOM   8726  C CA  . LEU B 1 365 ? 152.366 93.326  60.699  1.00 94.00  ? 385 LEU B CA  1 
ATOM   8727  C C   . LEU B 1 365 ? 150.848 93.399  60.551  1.00 90.81  ? 385 LEU B C   1 
ATOM   8728  O O   . LEU B 1 365 ? 150.348 93.662  59.459  1.00 90.29  ? 385 LEU B O   1 
ATOM   8729  C CB  . LEU B 1 365 ? 153.004 94.716  60.606  1.00 93.94  ? 385 LEU B CB  1 
ATOM   8730  C CG  . LEU B 1 365 ? 154.333 94.884  61.341  1.00 95.82  ? 385 LEU B CG  1 
ATOM   8731  C CD1 . LEU B 1 365 ? 155.186 95.962  60.691  1.00 96.86  ? 385 LEU B CD1 1 
ATOM   8732  C CD2 . LEU B 1 365 ? 154.101 95.227  62.805  1.00 96.46  ? 385 LEU B CD2 1 
ATOM   8733  N N   . THR B 1 366 ? 150.136 93.144  61.656  1.00 87.47  ? 386 THR B N   1 
ATOM   8734  C CA  . THR B 1 366 ? 148.683 93.136  61.661  1.00 84.44  ? 386 THR B CA  1 
ATOM   8735  C C   . THR B 1 366 ? 148.182 94.015  62.802  1.00 79.88  ? 386 THR B C   1 
ATOM   8736  O O   . THR B 1 366 ? 148.855 94.161  63.822  1.00 79.57  ? 386 THR B O   1 
ATOM   8737  C CB  . THR B 1 366 ? 148.126 91.713  61.789  1.00 85.37  ? 386 THR B CB  1 
ATOM   8738  O OG1 . THR B 1 366 ? 146.710 91.793  61.624  1.00 86.93  ? 386 THR B OG1 1 
ATOM   8739  C CG2 . THR B 1 366 ? 148.465 91.050  63.106  1.00 85.37  ? 386 THR B CG2 1 
ATOM   8740  N N   . LEU B 1 367 ? 146.973 94.559  62.627  1.00 75.08  ? 387 LEU B N   1 
ATOM   8741  C CA  . LEU B 1 367 ? 146.390 95.482  63.587  1.00 72.21  ? 387 LEU B CA  1 
ATOM   8742  C C   . LEU B 1 367 ? 145.941 94.746  64.849  1.00 72.61  ? 387 LEU B C   1 
ATOM   8743  O O   . LEU B 1 367 ? 145.603 95.389  65.839  1.00 72.84  ? 387 LEU B O   1 
ATOM   8744  C CB  . LEU B 1 367 ? 145.203 96.202  62.937  1.00 70.54  ? 387 LEU B CB  1 
ATOM   8745  C CG  . LEU B 1 367 ? 145.544 97.249  61.876  1.00 68.70  ? 387 LEU B CG  1 
ATOM   8746  C CD1 . LEU B 1 367 ? 144.272 97.831  61.275  1.00 67.82  ? 387 LEU B CD1 1 
ATOM   8747  C CD2 . LEU B 1 367 ? 146.410 98.362  62.451  1.00 68.11  ? 387 LEU B CD2 1 
ATOM   8748  N N   . LYS B 1 368 ? 145.938 93.408  64.819  1.00 73.88  ? 388 LYS B N   1 
ATOM   8749  C CA  . LYS B 1 368 ? 145.475 92.612  65.946  1.00 75.96  ? 388 LYS B CA  1 
ATOM   8750  C C   . LYS B 1 368 ? 146.383 92.829  67.155  1.00 76.52  ? 388 LYS B C   1 
ATOM   8751  O O   . LYS B 1 368 ? 145.911 92.852  68.290  1.00 76.36  ? 388 LYS B O   1 
ATOM   8752  C CB  . LYS B 1 368 ? 145.431 91.129  65.569  1.00 77.65  ? 388 LYS B CB  1 
ATOM   8753  C CG  . LYS B 1 368 ? 144.597 90.798  64.340  1.00 80.08  ? 388 LYS B CG  1 
ATOM   8754  C CD  . LYS B 1 368 ? 144.717 89.357  63.899  1.00 83.11  ? 388 LYS B CD  1 
ATOM   8755  C CE  . LYS B 1 368 ? 144.293 88.366  64.965  1.00 85.29  ? 388 LYS B CE  1 
ATOM   8756  N NZ  . LYS B 1 368 ? 142.940 88.661  65.499  1.00 85.27  ? 388 LYS B NZ  1 
ATOM   8757  N N   . THR B 1 369 ? 147.685 92.997  66.901  1.00 76.66  ? 389 THR B N   1 
ATOM   8758  C CA  . THR B 1 369 ? 148.661 93.170  67.963  1.00 77.03  ? 389 THR B CA  1 
ATOM   8759  C C   . THR B 1 369 ? 148.388 94.483  68.692  1.00 76.43  ? 389 THR B C   1 
ATOM   8760  O O   . THR B 1 369 ? 148.457 95.548  68.086  1.00 76.91  ? 389 THR B O   1 
ATOM   8761  C CB  . THR B 1 369 ? 150.090 93.133  67.406  1.00 78.42  ? 389 THR B CB  1 
ATOM   8762  O OG1 . THR B 1 369 ? 150.273 94.273  66.565  1.00 78.65  ? 389 THR B OG1 1 
ATOM   8763  C CG2 . THR B 1 369 ? 150.388 91.869  66.629  1.00 79.27  ? 389 THR B CG2 1 
ATOM   8764  N N   . HIS B 1 370 ? 148.069 94.392  69.990  1.00 76.23  ? 390 HIS B N   1 
ATOM   8765  C CA  . HIS B 1 370 ? 147.824 95.559  70.827  1.00 76.62  ? 390 HIS B CA  1 
ATOM   8766  C C   . HIS B 1 370 ? 146.655 96.364  70.262  1.00 70.26  ? 390 HIS B C   1 
ATOM   8767  O O   . HIS B 1 370 ? 146.787 97.560  70.004  1.00 70.12  ? 390 HIS B O   1 
ATOM   8768  C CB  . HIS B 1 370 ? 149.081 96.433  70.952  1.00 81.93  ? 390 HIS B CB  1 
ATOM   8769  C CG  . HIS B 1 370 ? 150.368 95.677  70.953  1.00 89.29  ? 390 HIS B CG  1 
ATOM   8770  N ND1 . HIS B 1 370 ? 150.865 94.953  72.015  1.00 93.92  ? 390 HIS B ND1 1 
ATOM   8771  C CD2 . HIS B 1 370 ? 151.255 95.539  69.959  1.00 92.70  ? 390 HIS B CD2 1 
ATOM   8772  C CE1 . HIS B 1 370 ? 152.021 94.407  71.664  1.00 96.21  ? 390 HIS B CE1 1 
ATOM   8773  N NE2 . HIS B 1 370 ? 152.278 94.750  70.419  1.00 95.17  ? 390 HIS B NE2 1 
ATOM   8774  N N   . HIS B 1 371 ? 145.514 95.694  70.067  1.00 63.55  ? 391 HIS B N   1 
ATOM   8775  C CA  . HIS B 1 371 ? 144.321 96.332  69.535  1.00 57.96  ? 391 HIS B CA  1 
ATOM   8776  C C   . HIS B 1 371 ? 143.343 96.638  70.664  1.00 53.46  ? 391 HIS B C   1 
ATOM   8777  O O   . HIS B 1 371 ? 143.017 95.763  71.461  1.00 52.80  ? 391 HIS B O   1 
ATOM   8778  C CB  . HIS B 1 371 ? 143.622 95.433  68.512  1.00 57.41  ? 391 HIS B CB  1 
ATOM   8779  C CG  . HIS B 1 371 ? 142.305 95.968  68.056  1.00 56.31  ? 391 HIS B CG  1 
ATOM   8780  N ND1 . HIS B 1 371 ? 142.169 97.171  67.397  1.00 55.54  ? 391 HIS B ND1 1 
ATOM   8781  C CD2 . HIS B 1 371 ? 141.070 95.471  68.178  1.00 55.91  ? 391 HIS B CD2 1 
ATOM   8782  C CE1 . HIS B 1 371 ? 140.889 97.378  67.124  1.00 54.83  ? 391 HIS B CE1 1 
ATOM   8783  N NE2 . HIS B 1 371 ? 140.204 96.358  67.591  1.00 55.20  ? 391 HIS B NE2 1 
ATOM   8784  N N   . VAL B 1 372 ? 142.868 97.886  70.697  1.00 50.03  ? 392 VAL B N   1 
ATOM   8785  C CA  . VAL B 1 372 ? 141.767 98.273  71.561  1.00 47.69  ? 392 VAL B CA  1 
ATOM   8786  C C   . VAL B 1 372 ? 140.758 99.036  70.711  1.00 45.46  ? 392 VAL B C   1 
ATOM   8787  O O   . VAL B 1 372 ? 141.142 99.888  69.913  1.00 45.88  ? 392 VAL B O   1 
ATOM   8788  C CB  . VAL B 1 372 ? 142.235 99.111  72.769  1.00 47.69  ? 392 VAL B CB  1 
ATOM   8789  C CG1 . VAL B 1 372 ? 143.013 98.270  73.770  1.00 48.76  ? 392 VAL B CG1 1 
ATOM   8790  C CG2 . VAL B 1 372 ? 143.040 100.337 72.354  1.00 47.51  ? 392 VAL B CG2 1 
ATOM   8791  N N   . GLN B 1 373 ? 139.472 98.722  70.890  1.00 43.09  ? 393 GLN B N   1 
ATOM   8792  C CA  . GLN B 1 373 ? 138.410 99.442  70.213  1.00 41.12  ? 393 GLN B CA  1 
ATOM   8793  C C   . GLN B 1 373 ? 137.969 100.608 71.090  1.00 39.10  ? 393 GLN B C   1 
ATOM   8794  O O   . GLN B 1 373 ? 137.799 100.442 72.297  1.00 39.48  ? 393 GLN B O   1 
ATOM   8795  C CB  . GLN B 1 373 ? 137.230 98.515  69.938  1.00 41.63  ? 393 GLN B CB  1 
ATOM   8796  C CG  . GLN B 1 373 ? 136.064 99.215  69.257  1.00 41.74  ? 393 GLN B CG  1 
ATOM   8797  C CD  . GLN B 1 373 ? 134.900 98.284  69.033  1.00 42.21  ? 393 GLN B CD  1 
ATOM   8798  O OE1 . GLN B 1 373 ? 133.765 98.571  69.409  1.00 43.10  ? 393 GLN B OE1 1 
ATOM   8799  N NE2 . GLN B 1 373 ? 135.176 97.155  68.403  1.00 42.67  ? 393 GLN B NE2 1 
ATOM   8800  N N   . ASP B 1 374 ? 137.755 101.772 70.470  1.00 37.02  ? 394 ASP B N   1 
ATOM   8801  C CA  . ASP B 1 374 ? 137.434 102.969 71.226  1.00 36.31  ? 394 ASP B CA  1 
ATOM   8802  C C   . ASP B 1 374 ? 136.072 102.785 71.886  1.00 35.08  ? 394 ASP B C   1 
ATOM   8803  O O   . ASP B 1 374 ? 135.190 102.120 71.348  1.00 34.48  ? 394 ASP B O   1 
ATOM   8804  C CB  . ASP B 1 374 ? 137.515 104.222 70.359  1.00 36.85  ? 394 ASP B CB  1 
ATOM   8805  C CG  . ASP B 1 374 ? 136.239 104.586 69.630  1.00 37.11  ? 394 ASP B CG  1 
ATOM   8806  O OD1 . ASP B 1 374 ? 135.546 103.664 69.186  1.00 36.95  ? 394 ASP B OD1 1 
ATOM   8807  O OD2 . ASP B 1 374 ? 135.948 105.789 69.527  1.00 36.76  ? 394 ASP B OD2 1 
ATOM   8808  N N   . SER B 1 375 ? 135.925 103.400 73.059  1.00 34.70  ? 395 SER B N   1 
ATOM   8809  C CA  . SER B 1 375 ? 134.791 103.151 73.928  1.00 34.54  ? 395 SER B CA  1 
ATOM   8810  C C   . SER B 1 375 ? 133.493 103.646 73.297  1.00 33.25  ? 395 SER B C   1 
ATOM   8811  O O   . SER B 1 375 ? 132.433 103.104 73.593  1.00 34.29  ? 395 SER B O   1 
ATOM   8812  C CB  . SER B 1 375 ? 135.012 103.767 75.286  1.00 35.25  ? 395 SER B CB  1 
ATOM   8813  O OG  . SER B 1 375 ? 135.456 105.113 75.172  1.00 35.87  ? 395 SER B OG  1 
ATOM   8814  N N   . LYS B 1 376 ? 133.579 104.648 72.415  1.00 31.41  ? 396 LYS B N   1 
ATOM   8815  C CA  . LYS B 1 376 ? 132.385 105.279 71.882  1.00 29.89  ? 396 LYS B CA  1 
ATOM   8816  C C   . LYS B 1 376 ? 132.136 104.845 70.445  1.00 28.76  ? 396 LYS B C   1 
ATOM   8817  O O   . LYS B 1 376 ? 131.618 105.630 69.662  1.00 28.25  ? 396 LYS B O   1 
ATOM   8818  C CB  . LYS B 1 376 ? 132.524 106.798 71.980  1.00 29.66  ? 396 LYS B CB  1 
ATOM   8819  C CG  . LYS B 1 376 ? 132.394 107.322 73.395  1.00 29.77  ? 396 LYS B CG  1 
ATOM   8820  C CD  . LYS B 1 376 ? 132.235 108.818 73.429  1.00 30.07  ? 396 LYS B CD  1 
ATOM   8821  C CE  . LYS B 1 376 ? 132.940 109.439 74.610  1.00 30.49  ? 396 LYS B CE  1 
ATOM   8822  N NZ  . LYS B 1 376 ? 134.402 109.190 74.559  1.00 30.45  ? 396 LYS B NZ  1 
ATOM   8823  N N   . MET B 1 377 ? 132.449 103.589 70.122  1.00 28.59  ? 397 MET B N   1 
ATOM   8824  C CA  . MET B 1 377 ? 132.222 103.088 68.776  1.00 28.58  ? 397 MET B CA  1 
ATOM   8825  C C   . MET B 1 377 ? 130.726 102.862 68.569  1.00 28.25  ? 397 MET B C   1 
ATOM   8826  O O   . MET B 1 377 ? 130.177 103.223 67.529  1.00 28.67  ? 397 MET B O   1 
ATOM   8827  C CB  . MET B 1 377 ? 132.976 101.777 68.549  1.00 29.11  ? 397 MET B CB  1 
ATOM   8828  C CG  . MET B 1 377 ? 132.668 101.105 67.230  1.00 29.49  ? 397 MET B CG  1 
ATOM   8829  S SD  . MET B 1 377 ? 133.516 101.750 65.747  1.00 30.23  ? 397 MET B SD  1 
ATOM   8830  C CE  . MET B 1 377 ? 134.766 102.870 66.379  1.00 30.34  ? 397 MET B CE  1 
ATOM   8831  N N   . GLY B 1 378 ? 130.082 102.255 69.569  1.00 27.47  ? 398 GLY B N   1 
ATOM   8832  C CA  . GLY B 1 378 ? 128.650 102.014 69.533  1.00 26.88  ? 398 GLY B CA  1 
ATOM   8833  C C   . GLY B 1 378 ? 127.870 103.277 69.186  1.00 26.18  ? 398 GLY B C   1 
ATOM   8834  O O   . GLY B 1 378 ? 126.975 103.238 68.353  1.00 26.85  ? 398 GLY B O   1 
ATOM   8835  N N   . PHE B 1 379 ? 128.204 104.381 69.854  1.00 25.06  ? 399 PHE B N   1 
ATOM   8836  C CA  . PHE B 1 379 ? 127.507 105.637 69.656  1.00 24.32  ? 399 PHE B CA  1 
ATOM   8837  C C   . PHE B 1 379 ? 127.686 106.113 68.218  1.00 24.02  ? 399 PHE B C   1 
ATOM   8838  O O   . PHE B 1 379 ? 126.757 106.640 67.619  1.00 24.83  ? 399 PHE B O   1 
ATOM   8839  C CB  . PHE B 1 379 ? 127.991 106.672 70.669  1.00 24.38  ? 399 PHE B CB  1 
ATOM   8840  C CG  . PHE B 1 379 ? 127.750 106.276 72.102  1.00 25.23  ? 399 PHE B CG  1 
ATOM   8841  C CD1 . PHE B 1 379 ? 126.475 105.981 72.556  1.00 25.82  ? 399 PHE B CD1 1 
ATOM   8842  C CD2 . PHE B 1 379 ? 128.803 106.186 72.998  1.00 25.91  ? 399 PHE B CD2 1 
ATOM   8843  C CE1 . PHE B 1 379 ? 126.259 105.612 73.875  1.00 26.29  ? 399 PHE B CE1 1 
ATOM   8844  C CE2 . PHE B 1 379 ? 128.585 105.822 74.318  1.00 26.06  ? 399 PHE B CE2 1 
ATOM   8845  C CZ  . PHE B 1 379 ? 127.313 105.541 74.756  1.00 26.27  ? 399 PHE B CZ  1 
ATOM   8846  N N   . VAL B 1 380 ? 128.897 105.982 67.676  1.00 23.68  ? 400 VAL B N   1 
ATOM   8847  C CA  . VAL B 1 380 ? 129.159 106.426 66.317  1.00 23.54  ? 400 VAL B CA  1 
ATOM   8848  C C   . VAL B 1 380 ? 128.230 105.682 65.363  1.00 24.16  ? 400 VAL B C   1 
ATOM   8849  O O   . VAL B 1 380 ? 127.559 106.295 64.539  1.00 24.48  ? 400 VAL B O   1 
ATOM   8850  C CB  . VAL B 1 380 ? 130.640 106.246 65.937  1.00 23.36  ? 400 VAL B CB  1 
ATOM   8851  C CG1 . VAL B 1 380 ? 130.882 106.376 64.443  1.00 23.43  ? 400 VAL B CG1 1 
ATOM   8852  C CG2 . VAL B 1 380 ? 131.511 107.231 66.697  1.00 23.55  ? 400 VAL B CG2 1 
ATOM   8853  N N   . ILE B 1 381 ? 128.188 104.354 65.491  1.00 25.07  ? 401 ILE B N   1 
ATOM   8854  C CA  . ILE B 1 381 ? 127.412 103.536 64.576  1.00 25.99  ? 401 ILE B CA  1 
ATOM   8855  C C   . ILE B 1 381 ? 125.931 103.846 64.781  1.00 26.20  ? 401 ILE B C   1 
ATOM   8856  O O   . ILE B 1 381 ? 125.176 103.877 63.813  1.00 26.91  ? 401 ILE B O   1 
ATOM   8857  C CB  . ILE B 1 381 ? 127.754 102.042 64.755  1.00 26.82  ? 401 ILE B CB  1 
ATOM   8858  C CG1 . ILE B 1 381 ? 129.252 101.796 64.550  1.00 27.25  ? 401 ILE B CG1 1 
ATOM   8859  C CG2 . ILE B 1 381 ? 126.904 101.172 63.840  1.00 27.39  ? 401 ILE B CG2 1 
ATOM   8860  C CD1 . ILE B 1 381 ? 129.677 100.359 64.692  1.00 27.74  ? 401 ILE B CD1 1 
ATOM   8861  N N   . ASN B 1 382 ? 125.518 104.065 66.034  1.00 26.08  ? 402 ASN B N   1 
ATOM   8862  C CA  . ASN B 1 382 ? 124.141 104.428 66.330  1.00 26.13  ? 402 ASN B CA  1 
ATOM   8863  C C   . ASN B 1 382 ? 123.778 105.751 65.664  1.00 26.26  ? 402 ASN B C   1 
ATOM   8864  O O   . ASN B 1 382 ? 122.660 105.896 65.178  1.00 27.08  ? 402 ASN B O   1 
ATOM   8865  C CB  . ASN B 1 382 ? 123.885 104.499 67.836  1.00 26.38  ? 402 ASN B CB  1 
ATOM   8866  C CG  . ASN B 1 382 ? 123.734 103.133 68.464  1.00 26.98  ? 402 ASN B CG  1 
ATOM   8867  O OD1 . ASN B 1 382 ? 123.724 102.123 67.765  1.00 27.51  ? 402 ASN B OD1 1 
ATOM   8868  N ND2 . ASN B 1 382 ? 123.604 103.093 69.780  1.00 27.40  ? 402 ASN B ND2 1 
ATOM   8869  N N   . ALA B 1 383 ? 124.679 106.739 65.704  1.00 26.07  ? 403 ALA B N   1 
ATOM   8870  C CA  . ALA B 1 383 ? 124.395 108.020 65.075  1.00 26.17  ? 403 ALA B CA  1 
ATOM   8871  C C   . ALA B 1 383 ? 124.188 107.828 63.573  1.00 26.62  ? 403 ALA B C   1 
ATOM   8872  O O   . ALA B 1 383 ? 123.258 108.381 62.998  1.00 27.05  ? 403 ALA B O   1 
ATOM   8873  C CB  . ALA B 1 383 ? 125.493 109.012 65.360  1.00 26.13  ? 403 ALA B CB  1 
ATOM   8874  N N   . ILE B 1 384 ? 125.046 107.030 62.936  1.00 27.40  ? 404 ILE B N   1 
ATOM   8875  C CA  . ILE B 1 384 ? 124.922 106.805 61.505  1.00 28.49  ? 404 ILE B CA  1 
ATOM   8876  C C   . ILE B 1 384 ? 123.599 106.101 61.217  1.00 29.89  ? 404 ILE B C   1 
ATOM   8877  O O   . ILE B 1 384 ? 122.880 106.497 60.308  1.00 30.62  ? 404 ILE B O   1 
ATOM   8878  C CB  . ILE B 1 384 ? 126.137 106.035 60.954  1.00 28.66  ? 404 ILE B CB  1 
ATOM   8879  C CG1 . ILE B 1 384 ? 127.428 106.834 61.150  1.00 28.60  ? 404 ILE B CG1 1 
ATOM   8880  C CG2 . ILE B 1 384 ? 125.922 105.675 59.492  1.00 28.70  ? 404 ILE B CG2 1 
ATOM   8881  C CD1 . ILE B 1 384 ? 128.653 105.981 61.305  1.00 28.57  ? 404 ILE B CD1 1 
ATOM   8882  N N   . TYR B 1 385 ? 123.278 105.070 62.002  1.00 31.45  ? 405 TYR B N   1 
ATOM   8883  C CA  . TYR B 1 385 ? 122.004 104.386 61.862  1.00 32.74  ? 405 TYR B CA  1 
ATOM   8884  C C   . TYR B 1 385 ? 120.846 105.347 62.109  1.00 32.47  ? 405 TYR B C   1 
ATOM   8885  O O   . TYR B 1 385 ? 119.810 105.226 61.465  1.00 33.04  ? 405 TYR B O   1 
ATOM   8886  C CB  . TYR B 1 385 ? 121.897 103.195 62.816  1.00 34.20  ? 405 TYR B CB  1 
ATOM   8887  C CG  . TYR B 1 385 ? 122.429 101.897 62.267  1.00 35.85  ? 405 TYR B CG  1 
ATOM   8888  C CD1 . TYR B 1 385 ? 122.173 101.513 60.959  1.00 37.07  ? 405 TYR B CD1 1 
ATOM   8889  C CD2 . TYR B 1 385 ? 123.144 101.024 63.070  1.00 37.19  ? 405 TYR B CD2 1 
ATOM   8890  C CE1 . TYR B 1 385 ? 122.645 100.316 60.450  1.00 38.30  ? 405 TYR B CE1 1 
ATOM   8891  C CE2 . TYR B 1 385 ? 123.617 99.819  62.580  1.00 38.47  ? 405 TYR B CE2 1 
ATOM   8892  C CZ  . TYR B 1 385 ? 123.364 99.463  61.268  1.00 39.09  ? 405 TYR B CZ  1 
ATOM   8893  O OH  . TYR B 1 385 ? 123.831 98.266  60.794  1.00 40.23  ? 405 TYR B OH  1 
ATOM   8894  N N   . SER B 1 386 ? 121.011 106.268 63.063  1.00 32.27  ? 406 SER B N   1 
ATOM   8895  C CA  . SER B 1 386 ? 119.963 107.225 63.376  1.00 32.22  ? 406 SER B CA  1 
ATOM   8896  C C   . SER B 1 386 ? 119.627 108.069 62.148  1.00 32.59  ? 406 SER B C   1 
ATOM   8897  O O   . SER B 1 386 ? 118.451 108.263 61.837  1.00 33.34  ? 406 SER B O   1 
ATOM   8898  C CB  . SER B 1 386 ? 120.335 108.084 64.555  1.00 32.01  ? 406 SER B CB  1 
ATOM   8899  O OG  . SER B 1 386 ? 119.364 109.096 64.757  1.00 32.42  ? 406 SER B OG  1 
ATOM   8900  N N   . MET B 1 387 ? 120.658 108.574 61.460  1.00 33.78  ? 407 MET B N   1 
ATOM   8901  C CA  . MET B 1 387 ? 120.454 109.395 60.276  1.00 35.27  ? 407 MET B CA  1 
ATOM   8902  C C   . MET B 1 387 ? 119.808 108.561 59.174  1.00 37.11  ? 407 MET B C   1 
ATOM   8903  O O   . MET B 1 387 ? 118.886 109.025 58.514  1.00 38.06  ? 407 MET B O   1 
ATOM   8904  C CB  . MET B 1 387 ? 121.774 109.955 59.748  1.00 35.62  ? 407 MET B CB  1 
ATOM   8905  C CG  . MET B 1 387 ? 121.603 110.995 58.660  1.00 36.00  ? 407 MET B CG  1 
ATOM   8906  S SD  . MET B 1 387 ? 121.198 112.639 59.314  1.00 37.09  ? 407 MET B SD  1 
ATOM   8907  C CE  . MET B 1 387 ? 122.621 112.995 60.347  1.00 36.94  ? 407 MET B CE  1 
ATOM   8908  N N   . ALA B 1 388 ? 120.271 107.314 59.014  1.00 39.62  ? 408 ALA B N   1 
ATOM   8909  C CA  . ALA B 1 388 ? 119.696 106.419 58.021  1.00 42.17  ? 408 ALA B CA  1 
ATOM   8910  C C   . ALA B 1 388 ? 118.205 106.232 58.290  1.00 45.00  ? 408 ALA B C   1 
ATOM   8911  O O   . ALA B 1 388 ? 117.392 106.387 57.382  1.00 46.93  ? 408 ALA B O   1 
ATOM   8912  C CB  . ALA B 1 388 ? 120.432 105.099 58.002  1.00 42.93  ? 408 ALA B CB  1 
ATOM   8913  N N   . TYR B 1 389 ? 117.852 105.909 59.538  1.00 47.19  ? 409 TYR B N   1 
ATOM   8914  C CA  . TYR B 1 389 ? 116.466 105.624 59.876  1.00 49.04  ? 409 TYR B CA  1 
ATOM   8915  C C   . TYR B 1 389 ? 115.601 106.864 59.671  1.00 48.14  ? 409 TYR B C   1 
ATOM   8916  O O   . TYR B 1 389 ? 114.455 106.749 59.251  1.00 49.28  ? 409 TYR B O   1 
ATOM   8917  C CB  . TYR B 1 389 ? 116.351 105.056 61.293  1.00 51.28  ? 409 TYR B CB  1 
ATOM   8918  C CG  . TYR B 1 389 ? 116.443 103.551 61.351  1.00 53.98  ? 409 TYR B CG  1 
ATOM   8919  C CD1 . TYR B 1 389 ? 117.650 102.887 61.186  1.00 55.75  ? 409 TYR B CD1 1 
ATOM   8920  C CD2 . TYR B 1 389 ? 115.305 102.783 61.527  1.00 56.22  ? 409 TYR B CD2 1 
ATOM   8921  C CE1 . TYR B 1 389 ? 117.725 101.504 61.215  1.00 57.37  ? 409 TYR B CE1 1 
ATOM   8922  C CE2 . TYR B 1 389 ? 115.363 101.400 61.563  1.00 57.85  ? 409 TYR B CE2 1 
ATOM   8923  C CZ  . TYR B 1 389 ? 116.577 100.756 61.407  1.00 58.48  ? 409 TYR B CZ  1 
ATOM   8924  O OH  . TYR B 1 389 ? 116.640 99.384  61.447  1.00 59.36  ? 409 TYR B OH  1 
ATOM   8925  N N   . GLY B 1 390 ? 116.134 108.044 60.003  1.00 47.40  ? 410 GLY B N   1 
ATOM   8926  C CA  . GLY B 1 390 ? 115.443 109.296 59.727  1.00 47.60  ? 410 GLY B CA  1 
ATOM   8927  C C   . GLY B 1 390 ? 115.092 109.424 58.246  1.00 48.30  ? 410 GLY B C   1 
ATOM   8928  O O   . GLY B 1 390 ? 113.934 109.656 57.893  1.00 49.76  ? 410 GLY B O   1 
ATOM   8929  N N   . LEU B 1 391 ? 116.110 109.276 57.389  1.00 49.05  ? 411 LEU B N   1 
ATOM   8930  C CA  . LEU B 1 391 ? 115.898 109.363 55.955  1.00 50.84  ? 411 LEU B CA  1 
ATOM   8931  C C   . LEU B 1 391 ? 114.869 108.319 55.534  1.00 54.66  ? 411 LEU B C   1 
ATOM   8932  O O   . LEU B 1 391 ? 114.016 108.603 54.700  1.00 56.76  ? 411 LEU B O   1 
ATOM   8933  C CB  . LEU B 1 391 ? 117.224 109.159 55.217  1.00 50.93  ? 411 LEU B CB  1 
ATOM   8934  C CG  . LEU B 1 391 ? 118.160 110.367 55.172  1.00 51.25  ? 411 LEU B CG  1 
ATOM   8935  C CD1 . LEU B 1 391 ? 119.504 109.972 54.580  1.00 51.13  ? 411 LEU B CD1 1 
ATOM   8936  C CD2 . LEU B 1 391 ? 117.560 111.513 54.371  1.00 52.17  ? 411 LEU B CD2 1 
ATOM   8937  N N   . HIS B 1 392 ? 114.974 107.106 56.093  1.00 58.03  ? 412 HIS B N   1 
ATOM   8938  C CA  . HIS B 1 392 ? 114.068 106.028 55.730  1.00 61.59  ? 412 HIS B CA  1 
ATOM   8939  C C   . HIS B 1 392 ? 112.629 106.416 56.057  1.00 64.48  ? 412 HIS B C   1 
ATOM   8940  O O   . HIS B 1 392 ? 111.730 106.222 55.240  1.00 67.37  ? 412 HIS B O   1 
ATOM   8941  C CB  . HIS B 1 392 ? 114.430 104.723 56.445  1.00 64.06  ? 412 HIS B CB  1 
ATOM   8942  C CG  . HIS B 1 392 ? 113.554 103.577 56.062  1.00 67.41  ? 412 HIS B CG  1 
ATOM   8943  N ND1 . HIS B 1 392 ? 112.709 102.967 56.963  1.00 68.92  ? 412 HIS B ND1 1 
ATOM   8944  C CD2 . HIS B 1 392 ? 113.381 102.932 54.897  1.00 69.08  ? 412 HIS B CD2 1 
ATOM   8945  C CE1 . HIS B 1 392 ? 112.064 101.980 56.360  1.00 70.01  ? 412 HIS B CE1 1 
ATOM   8946  N NE2 . HIS B 1 392 ? 112.449 101.947 55.102  1.00 70.22  ? 412 HIS B NE2 1 
ATOM   8947  N N   . ASN B 1 393 ? 112.415 106.938 57.270  1.00 66.20  ? 413 ASN B N   1 
ATOM   8948  C CA  . ASN B 1 393 ? 111.076 107.298 57.704  1.00 68.82  ? 413 ASN B CA  1 
ATOM   8949  C C   . ASN B 1 393 ? 110.521 108.395 56.801  1.00 72.12  ? 413 ASN B C   1 
ATOM   8950  O O   . ASN B 1 393 ? 109.363 108.321 56.389  1.00 73.71  ? 413 ASN B O   1 
ATOM   8951  C CB  . ASN B 1 393 ? 111.036 107.688 59.181  1.00 69.82  ? 413 ASN B CB  1 
ATOM   8952  C CG  . ASN B 1 393 ? 111.376 106.522 60.085  1.00 71.52  ? 413 ASN B CG  1 
ATOM   8953  O OD1 . ASN B 1 393 ? 111.611 105.413 59.609  1.00 71.20  ? 413 ASN B OD1 1 
ATOM   8954  N ND2 . ASN B 1 393 ? 111.418 106.763 61.383  1.00 72.39  ? 413 ASN B ND2 1 
ATOM   8955  N N   . MET B 1 394 ? 111.352 109.397 56.478  1.00 76.29  ? 414 MET B N   1 
ATOM   8956  C CA  . MET B 1 394 ? 110.914 110.445 55.572  1.00 80.42  ? 414 MET B CA  1 
ATOM   8957  C C   . MET B 1 394 ? 110.537 109.815 54.232  1.00 83.68  ? 414 MET B C   1 
ATOM   8958  O O   . MET B 1 394 ? 109.508 110.165 53.655  1.00 86.61  ? 414 MET B O   1 
ATOM   8959  C CB  . MET B 1 394 ? 111.987 111.512 55.331  1.00 81.46  ? 414 MET B CB  1 
ATOM   8960  C CG  . MET B 1 394 ? 111.618 112.433 54.178  1.00 83.76  ? 414 MET B CG  1 
ATOM   8961  S SD  . MET B 1 394 ? 112.935 113.525 53.596  1.00 85.59  ? 414 MET B SD  1 
ATOM   8962  C CE  . MET B 1 394 ? 113.515 114.166 55.162  1.00 82.90  ? 414 MET B CE  1 
ATOM   8963  N N   . GLN B 1 395 ? 111.374 108.891 53.736  1.00 85.94  ? 415 GLN B N   1 
ATOM   8964  C CA  . GLN B 1 395 ? 111.132 108.277 52.437  1.00 89.91  ? 415 GLN B CA  1 
ATOM   8965  C C   . GLN B 1 395 ? 109.792 107.546 52.457  1.00 92.94  ? 415 GLN B C   1 
ATOM   8966  O O   . GLN B 1 395 ? 109.063 107.589 51.468  1.00 94.44  ? 415 GLN B O   1 
ATOM   8967  C CB  . GLN B 1 395 ? 112.275 107.350 52.023  1.00 92.47  ? 415 GLN B CB  1 
ATOM   8968  C CG  . GLN B 1 395 ? 112.311 107.050 50.526  1.00 95.09  ? 415 GLN B CG  1 
ATOM   8969  C CD  . GLN B 1 395 ? 111.382 105.950 50.068  1.00 98.45  ? 415 GLN B CD  1 
ATOM   8970  O OE1 . GLN B 1 395 ? 110.667 105.332 50.854  1.00 98.61  ? 415 GLN B OE1 1 
ATOM   8971  N NE2 . GLN B 1 395 ? 111.374 105.698 48.773  1.00 101.47 ? 415 GLN B NE2 1 
ATOM   8972  N N   . MET B 1 396 ? 109.461 106.893 53.577  1.00 97.24  ? 416 MET B N   1 
ATOM   8973  C CA  . MET B 1 396 ? 108.200 106.175 53.683  1.00 102.84 ? 416 MET B CA  1 
ATOM   8974  C C   . MET B 1 396 ? 107.027 107.155 53.750  1.00 106.17 ? 416 MET B C   1 
ATOM   8975  O O   . MET B 1 396 ? 105.986 106.910 53.147  1.00 108.51 ? 416 MET B O   1 
ATOM   8976  C CB  . MET B 1 396 ? 108.176 105.271 54.918  1.00 105.13 ? 416 MET B CB  1 
ATOM   8977  C CG  . MET B 1 396 ? 108.887 103.951 54.703  1.00 107.52 ? 416 MET B CG  1 
ATOM   8978  S SD  . MET B 1 396 ? 108.529 102.713 55.980  1.00 113.01 ? 416 MET B SD  1 
ATOM   8979  C CE  . MET B 1 396 ? 108.427 103.727 57.456  1.00 114.19 ? 416 MET B CE  1 
ATOM   8980  N N   . SER B 1 397 ? 107.207 108.280 54.454  1.00 108.04 ? 417 SER B N   1 
ATOM   8981  C CA  . SER B 1 397 ? 106.096 109.182 54.734  1.00 109.91 ? 417 SER B CA  1 
ATOM   8982  C C   . SER B 1 397 ? 105.814 110.117 53.555  1.00 111.69 ? 417 SER B C   1 
ATOM   8983  O O   . SER B 1 397 ? 104.662 110.465 53.315  1.00 111.89 ? 417 SER B O   1 
ATOM   8984  C CB  . SER B 1 397 ? 106.334 109.955 56.003  1.00 110.26 ? 417 SER B CB  1 
ATOM   8985  O OG  . SER B 1 397 ? 105.250 110.833 56.272  1.00 110.38 ? 417 SER B OG  1 
ATOM   8986  N N   . LEU B 1 398 ? 106.861 110.503 52.815  1.00 114.97 ? 418 LEU B N   1 
ATOM   8987  C CA  . LEU B 1 398 ? 106.738 111.467 51.731  1.00 119.35 ? 418 LEU B CA  1 
ATOM   8988  C C   . LEU B 1 398 ? 106.454 110.769 50.401  1.00 124.86 ? 418 LEU B C   1 
ATOM   8989  O O   . LEU B 1 398 ? 105.688 111.294 49.595  1.00 126.42 ? 418 LEU B O   1 
ATOM   8990  C CB  . LEU B 1 398 ? 108.016 112.312 51.656  1.00 120.08 ? 418 LEU B CB  1 
ATOM   8991  C CG  . LEU B 1 398 ? 107.911 113.731 52.226  1.00 121.29 ? 418 LEU B CG  1 
ATOM   8992  C CD1 . LEU B 1 398 ? 107.451 113.729 53.680  1.00 120.90 ? 418 LEU B CD1 1 
ATOM   8993  C CD2 . LEU B 1 398 ? 109.242 114.463 52.103  1.00 121.56 ? 418 LEU B CD2 1 
ATOM   8994  N N   . CYS B 1 399 ? 107.071 109.600 50.170  1.00 131.27 ? 419 CYS B N   1 
ATOM   8995  C CA  . CYS B 1 399 ? 106.874 108.856 48.934  1.00 137.98 ? 419 CYS B CA  1 
ATOM   8996  C C   . CYS B 1 399 ? 106.559 107.395 49.250  1.00 140.38 ? 419 CYS B C   1 
ATOM   8997  O O   . CYS B 1 399 ? 107.417 106.528 49.100  1.00 141.83 ? 419 CYS B O   1 
ATOM   8998  C CB  . CYS B 1 399 ? 108.121 108.899 48.061  1.00 142.12 ? 419 CYS B CB  1 
ATOM   8999  S SG  . CYS B 1 399 ? 109.158 110.358 48.320  1.00 148.72 ? 419 CYS B SG  1 
ATOM   9000  N N   . PRO B 1 400 ? 105.335 107.070 49.726  1.00 142.63 ? 420 PRO B N   1 
ATOM   9001  C CA  . PRO B 1 400 ? 105.018 105.699 50.138  1.00 144.62 ? 420 PRO B CA  1 
ATOM   9002  C C   . PRO B 1 400 ? 105.088 104.695 48.985  1.00 146.47 ? 420 PRO B C   1 
ATOM   9003  O O   . PRO B 1 400 ? 105.707 103.637 49.109  1.00 145.65 ? 420 PRO B O   1 
ATOM   9004  C CB  . PRO B 1 400 ? 103.601 105.810 50.725  1.00 142.95 ? 420 PRO B CB  1 
ATOM   9005  C CG  . PRO B 1 400 ? 103.435 107.288 51.047  1.00 142.77 ? 420 PRO B CG  1 
ATOM   9006  C CD  . PRO B 1 400 ? 104.220 108.002 49.966  1.00 142.04 ? 420 PRO B CD  1 
ATOM   9007  N N   . GLY B 1 401 ? 104.475 105.052 47.851  1.00 148.73 ? 421 GLY B N   1 
ATOM   9008  C CA  . GLY B 1 401 ? 104.413 104.175 46.692  1.00 151.88 ? 421 GLY B CA  1 
ATOM   9009  C C   . GLY B 1 401 ? 105.791 103.910 46.088  1.00 154.74 ? 421 GLY B C   1 
ATOM   9010  O O   . GLY B 1 401 ? 106.166 102.760 45.870  1.00 154.36 ? 421 GLY B O   1 
ATOM   9011  N N   . TYR B 1 402 ? 106.538 104.991 45.830  1.00 157.64 ? 422 TYR B N   1 
ATOM   9012  C CA  . TYR B 1 402 ? 107.800 104.911 45.114  1.00 159.89 ? 422 TYR B CA  1 
ATOM   9013  C C   . TYR B 1 402 ? 108.875 104.315 46.019  1.00 157.27 ? 422 TYR B C   1 
ATOM   9014  O O   . TYR B 1 402 ? 109.050 104.750 47.158  1.00 155.66 ? 422 TYR B O   1 
ATOM   9015  C CB  . TYR B 1 402 ? 108.204 106.294 44.594  1.00 163.90 ? 422 TYR B CB  1 
ATOM   9016  C CG  . TYR B 1 402 ? 109.287 106.276 43.546  1.00 168.93 ? 422 TYR B CG  1 
ATOM   9017  C CD1 . TYR B 1 402 ? 110.626 106.248 43.899  1.00 171.91 ? 422 TYR B CD1 1 
ATOM   9018  C CD2 . TYR B 1 402 ? 108.976 106.261 42.196  1.00 172.29 ? 422 TYR B CD2 1 
ATOM   9019  C CE1 . TYR B 1 402 ? 111.630 106.219 42.944  1.00 174.39 ? 422 TYR B CE1 1 
ATOM   9020  C CE2 . TYR B 1 402 ? 109.965 106.236 41.226  1.00 174.82 ? 422 TYR B CE2 1 
ATOM   9021  C CZ  . TYR B 1 402 ? 111.298 106.215 41.600  1.00 176.06 ? 422 TYR B CZ  1 
ATOM   9022  O OH  . TYR B 1 402 ? 112.285 106.188 40.644  1.00 176.44 ? 422 TYR B OH  1 
ATOM   9023  N N   . ALA B 1 403 ? 109.587 103.313 45.487  1.00 156.52 ? 423 ALA B N   1 
ATOM   9024  C CA  . ALA B 1 403 ? 110.706 102.692 46.178  1.00 156.92 ? 423 ALA B CA  1 
ATOM   9025  C C   . ALA B 1 403 ? 112.004 103.371 45.747  1.00 155.43 ? 423 ALA B C   1 
ATOM   9026  O O   . ALA B 1 403 ? 112.793 102.803 44.997  1.00 155.37 ? 423 ALA B O   1 
ATOM   9027  C CB  . ALA B 1 403 ? 110.727 101.211 45.890  1.00 157.55 ? 423 ALA B CB  1 
ATOM   9028  N N   . GLY B 1 404 ? 112.181 104.612 46.204  1.00 152.52 ? 424 GLY B N   1 
ATOM   9029  C CA  . GLY B 1 404 ? 113.381 105.391 45.955  1.00 151.09 ? 424 GLY B CA  1 
ATOM   9030  C C   . GLY B 1 404 ? 113.132 106.878 46.190  1.00 149.90 ? 424 GLY B C   1 
ATOM   9031  O O   . GLY B 1 404 ? 112.161 107.245 46.852  1.00 149.02 ? 424 GLY B O   1 
ATOM   9032  N N   . LEU B 1 405 ? 114.015 107.720 45.641  1.00 149.64 ? 425 LEU B N   1 
ATOM   9033  C CA  . LEU B 1 405 ? 113.882 109.163 45.759  1.00 150.96 ? 425 LEU B CA  1 
ATOM   9034  C C   . LEU B 1 405 ? 112.811 109.652 44.789  1.00 153.33 ? 425 LEU B C   1 
ATOM   9035  O O   . LEU B 1 405 ? 113.055 109.749 43.586  1.00 152.41 ? 425 LEU B O   1 
ATOM   9036  C CB  . LEU B 1 405 ? 115.228 109.833 45.460  1.00 149.71 ? 425 LEU B CB  1 
ATOM   9037  C CG  . LEU B 1 405 ? 116.383 109.444 46.380  1.00 148.02 ? 425 LEU B CG  1 
ATOM   9038  C CD1 . LEU B 1 405 ? 117.555 110.397 46.204  1.00 148.28 ? 425 LEU B CD1 1 
ATOM   9039  C CD2 . LEU B 1 405 ? 115.954 109.411 47.841  1.00 146.70 ? 425 LEU B CD2 1 
ATOM   9040  N N   . CYS B 1 406 ? 111.633 109.993 45.329  1.00 154.81 ? 426 CYS B N   1 
ATOM   9041  C CA  . CYS B 1 406 ? 110.543 110.531 44.525  1.00 156.02 ? 426 CYS B CA  1 
ATOM   9042  C C   . CYS B 1 406 ? 110.819 112.002 44.203  1.00 157.12 ? 426 CYS B C   1 
ATOM   9043  O O   . CYS B 1 406 ? 111.808 112.564 44.664  1.00 155.91 ? 426 CYS B O   1 
ATOM   9044  C CB  . CYS B 1 406 ? 109.201 110.315 45.221  1.00 155.20 ? 426 CYS B CB  1 
ATOM   9045  S SG  . CYS B 1 406 ? 108.864 111.422 46.620  1.00 154.21 ? 426 CYS B SG  1 
ATOM   9046  N N   . ASP B 1 407 ? 109.955 112.619 43.383  1.00 160.36 ? 427 ASP B N   1 
ATOM   9047  C CA  . ASP B 1 407 ? 110.186 113.969 42.889  1.00 165.12 ? 427 ASP B CA  1 
ATOM   9048  C C   . ASP B 1 407 ? 110.165 114.978 44.039  1.00 163.33 ? 427 ASP B C   1 
ATOM   9049  O O   . ASP B 1 407 ? 110.947 115.929 44.043  1.00 163.24 ? 427 ASP B O   1 
ATOM   9050  C CB  . ASP B 1 407 ? 109.162 114.355 41.818  1.00 171.04 ? 427 ASP B CB  1 
ATOM   9051  C CG  . ASP B 1 407 ? 109.528 115.604 41.031  1.00 176.38 ? 427 ASP B CG  1 
ATOM   9052  O OD1 . ASP B 1 407 ? 110.679 116.071 41.161  1.00 176.96 ? 427 ASP B OD1 1 
ATOM   9053  O OD2 . ASP B 1 407 ? 108.653 116.105 40.296  1.00 178.78 ? 427 ASP B OD2 1 
ATOM   9054  N N   . ALA B 1 408 ? 109.279 114.760 45.018  1.00 159.75 ? 428 ALA B N   1 
ATOM   9055  C CA  . ALA B 1 408 ? 109.169 115.653 46.164  1.00 157.59 ? 428 ALA B CA  1 
ATOM   9056  C C   . ALA B 1 408 ? 110.331 115.456 47.139  1.00 155.42 ? 428 ALA B C   1 
ATOM   9057  O O   . ALA B 1 408 ? 110.465 116.215 48.094  1.00 155.29 ? 428 ALA B O   1 
ATOM   9058  C CB  . ALA B 1 408 ? 107.841 115.451 46.854  1.00 156.82 ? 428 ALA B CB  1 
ATOM   9059  N N   . MET B 1 409 ? 111.175 114.444 46.895  1.00 152.11 ? 429 MET B N   1 
ATOM   9060  C CA  . MET B 1 409 ? 112.265 114.088 47.794  1.00 148.37 ? 429 MET B CA  1 
ATOM   9061  C C   . MET B 1 409 ? 113.618 114.490 47.195  1.00 146.57 ? 429 MET B C   1 
ATOM   9062  O O   . MET B 1 409 ? 114.615 114.520 47.904  1.00 145.22 ? 429 MET B O   1 
ATOM   9063  C CB  . MET B 1 409 ? 112.216 112.580 48.067  1.00 147.39 ? 429 MET B CB  1 
ATOM   9064  C CG  . MET B 1 409 ? 113.488 111.966 48.640  1.00 147.16 ? 429 MET B CG  1 
ATOM   9065  S SD  . MET B 1 409 ? 113.151 110.558 49.724  1.00 147.21 ? 429 MET B SD  1 
ATOM   9066  C CE  . MET B 1 409 ? 112.067 111.334 50.919  1.00 141.52 ? 429 MET B CE  1 
ATOM   9067  N N   . LYS B 1 410 ? 113.656 114.842 45.902  1.00 145.80 ? 430 LYS B N   1 
ATOM   9068  C CA  . LYS B 1 410 ? 114.897 115.242 45.257  1.00 145.62 ? 430 LYS B CA  1 
ATOM   9069  C C   . LYS B 1 410 ? 115.546 116.394 46.023  1.00 141.84 ? 430 LYS B C   1 
ATOM   9070  O O   . LYS B 1 410 ? 116.729 116.308 46.347  1.00 143.97 ? 430 LYS B O   1 
ATOM   9071  C CB  . LYS B 1 410 ? 114.665 115.571 43.778  1.00 148.12 ? 430 LYS B CB  1 
ATOM   9072  C CG  . LYS B 1 410 ? 114.150 114.410 42.937  1.00 150.96 ? 430 LYS B CG  1 
ATOM   9073  C CD  . LYS B 1 410 ? 114.966 113.135 43.037  1.00 152.61 ? 430 LYS B CD  1 
ATOM   9074  C CE  . LYS B 1 410 ? 116.407 113.316 42.606  1.00 154.01 ? 430 LYS B CE  1 
ATOM   9075  N NZ  . LYS B 1 410 ? 117.171 112.053 42.718  1.00 154.67 ? 430 LYS B NZ  1 
ATOM   9076  N N   . PRO B 1 411 ? 114.828 117.494 46.360  1.00 133.30 ? 431 PRO B N   1 
ATOM   9077  C CA  . PRO B 1 411 ? 115.383 118.528 47.230  1.00 127.33 ? 431 PRO B CA  1 
ATOM   9078  C C   . PRO B 1 411 ? 115.043 118.222 48.686  1.00 120.17 ? 431 PRO B C   1 
ATOM   9079  O O   . PRO B 1 411 ? 114.051 118.719 49.216  1.00 120.40 ? 431 PRO B O   1 
ATOM   9080  C CB  . PRO B 1 411 ? 114.696 119.791 46.692  1.00 129.98 ? 431 PRO B CB  1 
ATOM   9081  C CG  . PRO B 1 411 ? 113.329 119.313 46.215  1.00 132.18 ? 431 PRO B CG  1 
ATOM   9082  C CD  . PRO B 1 411 ? 113.458 117.826 45.939  1.00 132.10 ? 431 PRO B CD  1 
ATOM   9083  N N   . ILE B 1 412 ? 115.868 117.383 49.323  1.00 113.00 ? 432 ILE B N   1 
ATOM   9084  C CA  . ILE B 1 412 ? 115.586 116.915 50.672  1.00 107.48 ? 432 ILE B CA  1 
ATOM   9085  C C   . ILE B 1 412 ? 115.531 118.127 51.598  1.00 105.64 ? 432 ILE B C   1 
ATOM   9086  O O   . ILE B 1 412 ? 116.503 118.871 51.715  1.00 107.46 ? 432 ILE B O   1 
ATOM   9087  C CB  . ILE B 1 412 ? 116.611 115.864 51.149  1.00 104.39 ? 432 ILE B CB  1 
ATOM   9088  C CG1 . ILE B 1 412 ? 116.662 114.666 50.197  1.00 103.03 ? 432 ILE B CG1 1 
ATOM   9089  C CG2 . ILE B 1 412 ? 116.311 115.427 52.577  1.00 103.47 ? 432 ILE B CG2 1 
ATOM   9090  C CD1 . ILE B 1 412 ? 117.678 113.616 50.555  1.00 101.73 ? 432 ILE B CD1 1 
ATOM   9091  N N   . ASP B 1 413 ? 114.374 118.314 52.242  1.00 102.88 ? 433 ASP B N   1 
ATOM   9092  C CA  . ASP B 1 413 ? 114.170 119.432 53.147  1.00 101.82 ? 433 ASP B CA  1 
ATOM   9093  C C   . ASP B 1 413 ? 114.718 119.060 54.521  1.00 95.32  ? 433 ASP B C   1 
ATOM   9094  O O   . ASP B 1 413 ? 114.325 118.055 55.109  1.00 93.47  ? 433 ASP B O   1 
ATOM   9095  C CB  . ASP B 1 413 ? 112.697 119.847 53.224  1.00 106.92 ? 433 ASP B CB  1 
ATOM   9096  C CG  . ASP B 1 413 ? 112.311 120.966 52.269  1.00 111.12 ? 433 ASP B CG  1 
ATOM   9097  O OD1 . ASP B 1 413 ? 113.180 121.406 51.486  1.00 112.13 ? 433 ASP B OD1 1 
ATOM   9098  O OD2 . ASP B 1 413 ? 111.148 121.408 52.335  1.00 112.81 ? 433 ASP B OD2 1 
ATOM   9099  N N   . GLY B 1 414 ? 115.624 119.900 55.032  1.00 90.54  ? 434 GLY B N   1 
ATOM   9100  C CA  . GLY B 1 414 ? 116.237 119.678 56.329  1.00 86.94  ? 434 GLY B CA  1 
ATOM   9101  C C   . GLY B 1 414 ? 115.239 119.737 57.482  1.00 84.54  ? 434 GLY B C   1 
ATOM   9102  O O   . GLY B 1 414 ? 115.471 119.108 58.510  1.00 82.70  ? 434 GLY B O   1 
ATOM   9103  N N   . ARG B 1 415 ? 114.147 120.495 57.309  1.00 84.45  ? 435 ARG B N   1 
ATOM   9104  C CA  . ARG B 1 415 ? 113.130 120.647 58.338  1.00 85.36  ? 435 ARG B CA  1 
ATOM   9105  C C   . ARG B 1 415 ? 112.410 119.319 58.567  1.00 83.38  ? 435 ARG B C   1 
ATOM   9106  O O   . ARG B 1 415 ? 112.269 118.876 59.707  1.00 82.76  ? 435 ARG B O   1 
ATOM   9107  C CB  . ARG B 1 415 ? 112.129 121.743 57.951  1.00 89.06  ? 435 ARG B CB  1 
ATOM   9108  C CG  . ARG B 1 415 ? 112.625 123.158 58.203  1.00 93.20  ? 435 ARG B CG  1 
ATOM   9109  C CD  . ARG B 1 415 ? 111.559 124.206 57.948  1.00 96.78  ? 435 ARG B CD  1 
ATOM   9110  N NE  . ARG B 1 415 ? 110.914 124.057 56.649  1.00 99.79  ? 435 ARG B NE  1 
ATOM   9111  C CZ  . ARG B 1 415 ? 111.505 124.239 55.470  1.00 101.76 ? 435 ARG B CZ  1 
ATOM   9112  N NH1 . ARG B 1 415 ? 112.768 124.623 55.396  1.00 101.36 ? 435 ARG B NH1 1 
ATOM   9113  N NH2 . ARG B 1 415 ? 110.816 124.058 54.356  1.00 102.21 ? 435 ARG B NH2 1 
ATOM   9114  N N   . LYS B 1 416 ? 111.965 118.692 57.472  1.00 81.32  ? 436 LYS B N   1 
ATOM   9115  C CA  . LYS B 1 416 ? 111.272 117.415 57.529  1.00 79.97  ? 436 LYS B CA  1 
ATOM   9116  C C   . LYS B 1 416 ? 112.217 116.345 58.076  1.00 74.44  ? 436 LYS B C   1 
ATOM   9117  O O   . LYS B 1 416 ? 111.794 115.489 58.852  1.00 74.22  ? 436 LYS B O   1 
ATOM   9118  C CB  . LYS B 1 416 ? 110.769 117.007 56.139  1.00 83.49  ? 436 LYS B CB  1 
ATOM   9119  C CG  . LYS B 1 416 ? 110.064 118.100 55.347  1.00 87.30  ? 436 LYS B CG  1 
ATOM   9120  C CD  . LYS B 1 416 ? 108.705 118.474 55.893  1.00 90.36  ? 436 LYS B CD  1 
ATOM   9121  C CE  . LYS B 1 416 ? 107.641 117.431 55.613  1.00 92.01  ? 436 LYS B CE  1 
ATOM   9122  N NZ  . LYS B 1 416 ? 107.381 117.269 54.160  1.00 92.84  ? 436 LYS B NZ  1 
ATOM   9123  N N   . LEU B 1 417 ? 113.493 116.404 57.665  1.00 68.53  ? 437 LEU B N   1 
ATOM   9124  C CA  . LEU B 1 417 ? 114.479 115.435 58.111  1.00 63.87  ? 437 LEU B CA  1 
ATOM   9125  C C   . LEU B 1 417 ? 114.681 115.570 59.615  1.00 61.21  ? 437 LEU B C   1 
ATOM   9126  O O   . LEU B 1 417 ? 114.758 114.560 60.312  1.00 60.50  ? 437 LEU B O   1 
ATOM   9127  C CB  . LEU B 1 417 ? 115.800 115.630 57.357  1.00 62.93  ? 437 LEU B CB  1 
ATOM   9128  C CG  . LEU B 1 417 ? 116.938 114.683 57.746  1.00 60.99  ? 437 LEU B CG  1 
ATOM   9129  C CD1 . LEU B 1 417 ? 116.540 113.225 57.619  1.00 59.67  ? 437 LEU B CD1 1 
ATOM   9130  C CD2 . LEU B 1 417 ? 118.166 114.945 56.890  1.00 60.61  ? 437 LEU B CD2 1 
ATOM   9131  N N   . LEU B 1 418 ? 114.764 116.814 60.103  1.00 61.26  ? 438 LEU B N   1 
ATOM   9132  C CA  . LEU B 1 418 ? 114.957 117.042 61.525  1.00 62.22  ? 438 LEU B CA  1 
ATOM   9133  C C   . LEU B 1 418 ? 113.757 116.493 62.290  1.00 65.43  ? 438 LEU B C   1 
ATOM   9134  O O   . LEU B 1 418 ? 113.931 115.883 63.342  1.00 65.40  ? 438 LEU B O   1 
ATOM   9135  C CB  . LEU B 1 418 ? 115.177 118.534 61.798  1.00 60.77  ? 438 LEU B CB  1 
ATOM   9136  C CG  . LEU B 1 418 ? 115.038 119.001 63.249  1.00 59.86  ? 438 LEU B CG  1 
ATOM   9137  C CD1 . LEU B 1 418 ? 115.997 118.281 64.188  1.00 60.17  ? 438 LEU B CD1 1 
ATOM   9138  C CD2 . LEU B 1 418 ? 115.255 120.497 63.339  1.00 58.73  ? 438 LEU B CD2 1 
ATOM   9139  N N   . GLU B 1 419 ? 112.550 116.703 61.750  1.00 68.48  ? 439 GLU B N   1 
ATOM   9140  C CA  . GLU B 1 419 ? 111.334 116.261 62.410  1.00 70.16  ? 439 GLU B CA  1 
ATOM   9141  C C   . GLU B 1 419 ? 111.331 114.737 62.525  1.00 66.86  ? 439 GLU B C   1 
ATOM   9142  O O   . GLU B 1 419 ? 111.128 114.196 63.610  1.00 66.72  ? 439 GLU B O   1 
ATOM   9143  C CB  . GLU B 1 419 ? 110.114 116.781 61.647  1.00 74.03  ? 439 GLU B CB  1 
ATOM   9144  C CG  . GLU B 1 419 ? 108.836 116.729 62.453  1.00 78.11  ? 439 GLU B CG  1 
ATOM   9145  C CD  . GLU B 1 419 ? 109.002 117.145 63.905  1.00 81.70  ? 439 GLU B CD  1 
ATOM   9146  O OE1 . GLU B 1 419 ? 109.370 118.314 64.144  1.00 83.04  ? 439 GLU B OE1 1 
ATOM   9147  O OE2 . GLU B 1 419 ? 108.793 116.292 64.792  1.00 83.27  ? 439 GLU B OE2 1 
ATOM   9148  N N   . SER B 1 420 ? 111.580 114.057 61.399  1.00 63.86  ? 440 SER B N   1 
ATOM   9149  C CA  . SER B 1 420 ? 111.588 112.603 61.366  1.00 62.55  ? 440 SER B CA  1 
ATOM   9150  C C   . SER B 1 420 ? 112.670 112.052 62.291  1.00 61.52  ? 440 SER B C   1 
ATOM   9151  O O   . SER B 1 420 ? 112.419 111.115 63.045  1.00 62.08  ? 440 SER B O   1 
ATOM   9152  C CB  . SER B 1 420 ? 111.756 112.092 59.958  1.00 62.83  ? 440 SER B CB  1 
ATOM   9153  O OG  . SER B 1 420 ? 110.642 112.459 59.159  1.00 63.47  ? 440 SER B OG  1 
ATOM   9154  N N   . LEU B 1 421 ? 113.871 112.640 62.233  1.00 60.36  ? 441 LEU B N   1 
ATOM   9155  C CA  . LEU B 1 421 ? 114.964 112.230 63.102  1.00 58.81  ? 441 LEU B CA  1 
ATOM   9156  C C   . LEU B 1 421 ? 114.563 112.390 64.564  1.00 59.66  ? 441 LEU B C   1 
ATOM   9157  O O   . LEU B 1 421 ? 114.998 111.611 65.405  1.00 59.87  ? 441 LEU B O   1 
ATOM   9158  C CB  . LEU B 1 421 ? 116.214 113.056 62.786  1.00 56.60  ? 441 LEU B CB  1 
ATOM   9159  C CG  . LEU B 1 421 ? 116.992 112.590 61.558  1.00 55.06  ? 441 LEU B CG  1 
ATOM   9160  C CD1 . LEU B 1 421 ? 118.099 113.568 61.197  1.00 54.44  ? 441 LEU B CD1 1 
ATOM   9161  C CD2 . LEU B 1 421 ? 117.568 111.208 61.811  1.00 54.63  ? 441 LEU B CD2 1 
ATOM   9162  N N   . MET B 1 422 ? 113.755 113.410 64.864  1.00 62.00  ? 442 MET B N   1 
ATOM   9163  C CA  . MET B 1 422 ? 113.366 113.668 66.238  1.00 64.69  ? 442 MET B CA  1 
ATOM   9164  C C   . MET B 1 422 ? 112.400 112.593 66.728  1.00 66.50  ? 442 MET B C   1 
ATOM   9165  O O   . MET B 1 422 ? 112.492 112.172 67.878  1.00 66.27  ? 442 MET B O   1 
ATOM   9166  C CB  . MET B 1 422 ? 112.740 115.059 66.382  1.00 66.24  ? 442 MET B CB  1 
ATOM   9167  C CG  . MET B 1 422 ? 113.774 116.123 66.690  1.00 66.56  ? 442 MET B CG  1 
ATOM   9168  S SD  . MET B 1 422 ? 114.509 115.844 68.325  1.00 66.92  ? 442 MET B SD  1 
ATOM   9169  C CE  . MET B 1 422 ? 115.444 117.357 68.527  1.00 67.45  ? 442 MET B CE  1 
ATOM   9170  N N   . LYS B 1 423 ? 111.500 112.127 65.854  1.00 69.40  ? 443 LYS B N   1 
ATOM   9171  C CA  . LYS B 1 423 ? 110.466 111.193 66.275  1.00 72.46  ? 443 LYS B CA  1 
ATOM   9172  C C   . LYS B 1 423 ? 110.891 109.741 66.044  1.00 72.70  ? 443 LYS B C   1 
ATOM   9173  O O   . LYS B 1 423 ? 110.176 108.833 66.462  1.00 73.14  ? 443 LYS B O   1 
ATOM   9174  C CB  . LYS B 1 423 ? 109.147 111.489 65.557  1.00 74.96  ? 443 LYS B CB  1 
ATOM   9175  C CG  . LYS B 1 423 ? 109.170 111.275 64.049  1.00 77.53  ? 443 LYS B CG  1 
ATOM   9176  C CD  . LYS B 1 423 ? 107.799 111.285 63.414  1.00 79.62  ? 443 LYS B CD  1 
ATOM   9177  C CE  . LYS B 1 423 ? 107.037 112.574 63.643  1.00 80.41  ? 443 LYS B CE  1 
ATOM   9178  N NZ  . LYS B 1 423 ? 107.809 113.758 63.195  1.00 80.45  ? 443 LYS B NZ  1 
ATOM   9179  N N   . THR B 1 424 ? 112.043 109.519 65.395  1.00 72.26  ? 444 THR B N   1 
ATOM   9180  C CA  . THR B 1 424 ? 112.465 108.167 65.055  1.00 72.41  ? 444 THR B CA  1 
ATOM   9181  C C   . THR B 1 424 ? 112.932 107.427 66.305  1.00 71.45  ? 444 THR B C   1 
ATOM   9182  O O   . THR B 1 424 ? 113.462 108.031 67.233  1.00 71.46  ? 444 THR B O   1 
ATOM   9183  C CB  . THR B 1 424 ? 113.567 108.137 63.984  1.00 72.74  ? 444 THR B CB  1 
ATOM   9184  O OG1 . THR B 1 424 ? 113.696 106.796 63.507  1.00 72.40  ? 444 THR B OG1 1 
ATOM   9185  C CG2 . THR B 1 424 ? 114.915 108.619 64.472  1.00 72.43  ? 444 THR B CG2 1 
ATOM   9186  N N   . ALA B 1 425 ? 112.729 106.106 66.286  1.00 71.02  ? 445 ALA B N   1 
ATOM   9187  C CA  . ALA B 1 425 ? 113.279 105.202 67.280  1.00 71.06  ? 445 ALA B CA  1 
ATOM   9188  C C   . ALA B 1 425 ? 113.522 103.850 66.617  1.00 73.09  ? 445 ALA B C   1 
ATOM   9189  O O   . ALA B 1 425 ? 112.793 103.471 65.702  1.00 73.34  ? 445 ALA B O   1 
ATOM   9190  C CB  . ALA B 1 425 ? 112.344 105.089 68.458  1.00 70.50  ? 445 ALA B CB  1 
ATOM   9191  N N   . PHE B 1 426 ? 114.556 103.134 67.073  1.00 75.67  ? 446 PHE B N   1 
ATOM   9192  C CA  . PHE B 1 426 ? 114.951 101.885 66.440  1.00 77.92  ? 446 PHE B CA  1 
ATOM   9193  C C   . PHE B 1 426 ? 115.820 101.079 67.400  1.00 80.30  ? 446 PHE B C   1 
ATOM   9194  O O   . PHE B 1 426 ? 115.965 101.454 68.554  1.00 79.77  ? 446 PHE B O   1 
ATOM   9195  C CB  . PHE B 1 426 ? 115.652 102.194 65.117  1.00 77.80  ? 446 PHE B CB  1 
ATOM   9196  C CG  . PHE B 1 426 ? 116.961 102.930 65.248  1.00 78.11  ? 446 PHE B CG  1 
ATOM   9197  C CD1 . PHE B 1 426 ? 117.020 104.262 65.641  1.00 78.77  ? 446 PHE B CD1 1 
ATOM   9198  C CD2 . PHE B 1 426 ? 118.150 102.268 64.994  1.00 78.23  ? 446 PHE B CD2 1 
ATOM   9199  C CE1 . PHE B 1 426 ? 118.238 104.914 65.761  1.00 78.07  ? 446 PHE B CE1 1 
ATOM   9200  C CE2 . PHE B 1 426 ? 119.366 102.926 65.099  1.00 78.35  ? 446 PHE B CE2 1 
ATOM   9201  C CZ  . PHE B 1 426 ? 119.410 104.252 65.467  1.00 77.53  ? 446 PHE B CZ  1 
ATOM   9202  N N   . THR B 1 427 ? 116.377 99.964  66.918  1.00 84.33  ? 447 THR B N   1 
ATOM   9203  C CA  . THR B 1 427 ? 117.244 99.126  67.733  1.00 87.22  ? 447 THR B CA  1 
ATOM   9204  C C   . THR B 1 427 ? 118.695 99.380  67.335  1.00 87.74  ? 447 THR B C   1 
ATOM   9205  O O   . THR B 1 427 ? 119.053 99.240  66.167  1.00 87.32  ? 447 THR B O   1 
ATOM   9206  C CB  . THR B 1 427 ? 116.867 97.647  67.592  1.00 89.04  ? 447 THR B CB  1 
ATOM   9207  O OG1 . THR B 1 427 ? 117.106 97.250  66.241  1.00 89.04  ? 447 THR B OG1 1 
ATOM   9208  C CG2 . THR B 1 427 ? 115.424 97.386  67.965  1.00 90.17  ? 447 THR B CG2 1 
ATOM   9209  N N   . GLY B 1 428 ? 119.517 99.750  68.322  1.00 88.85  ? 448 GLY B N   1 
ATOM   9210  C CA  . GLY B 1 428 ? 120.930 100.002 68.096  1.00 89.25  ? 448 GLY B CA  1 
ATOM   9211  C C   . GLY B 1 428 ? 121.721 98.705  67.948  1.00 90.34  ? 448 GLY B C   1 
ATOM   9212  O O   . GLY B 1 428 ? 121.177 97.612  68.086  1.00 91.27  ? 448 GLY B O   1 
ATOM   9213  N N   . VAL B 1 429 ? 123.014 98.858  67.659  1.00 90.07  ? 449 VAL B N   1 
ATOM   9214  C CA  . VAL B 1 429 ? 123.924 97.736  67.502  1.00 90.36  ? 449 VAL B CA  1 
ATOM   9215  C C   . VAL B 1 429 ? 124.048 96.977  68.821  1.00 93.12  ? 449 VAL B C   1 
ATOM   9216  O O   . VAL B 1 429 ? 124.173 95.753  68.818  1.00 92.75  ? 449 VAL B O   1 
ATOM   9217  C CB  . VAL B 1 429 ? 125.296 98.207  66.982  1.00 87.17  ? 449 VAL B CB  1 
ATOM   9218  C CG1 . VAL B 1 429 ? 125.229 98.541  65.503  1.00 85.24  ? 449 VAL B CG1 1 
ATOM   9219  C CG2 . VAL B 1 429 ? 125.853 99.384  67.776  1.00 85.65  ? 449 VAL B CG2 1 
ATOM   9220  N N   . SER B 1 430 ? 124.009 97.710  69.941  1.00 96.05  ? 450 SER B N   1 
ATOM   9221  C CA  . SER B 1 430 ? 124.100 97.110  71.263  1.00 98.74  ? 450 SER B CA  1 
ATOM   9222  C C   . SER B 1 430 ? 122.921 96.169  71.502  1.00 99.69  ? 450 SER B C   1 
ATOM   9223  O O   . SER B 1 430 ? 123.099 95.087  72.059  1.00 100.52 ? 450 SER B O   1 
ATOM   9224  C CB  . SER B 1 430 ? 124.186 98.169  72.335  1.00 99.30  ? 450 SER B CB  1 
ATOM   9225  O OG  . SER B 1 430 ? 123.090 99.065  72.248  1.00 99.22  ? 450 SER B OG  1 
ATOM   9226  N N   . GLY B 1 431 ? 121.723 96.591  71.076  1.00 99.45  ? 451 GLY B N   1 
ATOM   9227  C CA  . GLY B 1 431 ? 120.526 95.773  71.198  1.00 99.87  ? 451 GLY B CA  1 
ATOM   9228  C C   . GLY B 1 431 ? 119.352 96.560  71.773  1.00 100.11 ? 451 GLY B C   1 
ATOM   9229  O O   . GLY B 1 431 ? 118.205 96.337  71.388  1.00 101.25 ? 451 GLY B O   1 
ATOM   9230  N N   . ASP B 1 432 ? 119.655 97.482  72.696  1.00 99.00  ? 452 ASP B N   1 
ATOM   9231  C CA  . ASP B 1 432 ? 118.643 98.328  73.308  1.00 97.95  ? 452 ASP B CA  1 
ATOM   9232  C C   . ASP B 1 432 ? 118.098 99.308  72.270  1.00 92.85  ? 452 ASP B C   1 
ATOM   9233  O O   . ASP B 1 432 ? 118.710 99.535  71.224  1.00 92.00  ? 452 ASP B O   1 
ATOM   9234  C CB  . ASP B 1 432 ? 119.205 99.068  74.525  1.00 100.71 ? 452 ASP B CB  1 
ATOM   9235  C CG  . ASP B 1 432 ? 120.349 100.015 74.201  1.00 103.08 ? 452 ASP B CG  1 
ATOM   9236  O OD1 . ASP B 1 432 ? 120.820 99.986  73.042  1.00 104.44 ? 452 ASP B OD1 1 
ATOM   9237  O OD2 . ASP B 1 432 ? 120.723 100.799 75.089  1.00 102.78 ? 452 ASP B OD2 1 
ATOM   9238  N N   . THR B 1 433 ? 116.929 99.876  72.580  1.00 89.11  ? 453 THR B N   1 
ATOM   9239  C CA  . THR B 1 433 ? 116.255 100.789 71.675  1.00 86.48  ? 453 THR B CA  1 
ATOM   9240  C C   . THR B 1 433 ? 116.817 102.197 71.854  1.00 81.02  ? 453 THR B C   1 
ATOM   9241  O O   . THR B 1 433 ? 117.167 102.595 72.964  1.00 79.81  ? 453 THR B O   1 
ATOM   9242  C CB  . THR B 1 433 ? 114.734 100.760 71.879  1.00 88.81  ? 453 THR B CB  1 
ATOM   9243  O OG1 . THR B 1 433 ? 114.130 101.395 70.751  1.00 88.76  ? 453 THR B OG1 1 
ATOM   9244  C CG2 . THR B 1 433 ? 114.289 101.436 73.158  1.00 89.98  ? 453 THR B CG2 1 
ATOM   9245  N N   . ILE B 1 434 ? 116.867 102.940 70.741  1.00 76.32  ? 454 ILE B N   1 
ATOM   9246  C CA  . ILE B 1 434 ? 117.371 104.304 70.723  1.00 72.82  ? 454 ILE B CA  1 
ATOM   9247  C C   . ILE B 1 434 ? 116.220 105.234 70.347  1.00 70.37  ? 454 ILE B C   1 
ATOM   9248  O O   . ILE B 1 434 ? 115.501 104.975 69.379  1.00 70.78  ? 454 ILE B O   1 
ATOM   9249  C CB  . ILE B 1 434 ? 118.559 104.456 69.747  1.00 72.56  ? 454 ILE B CB  1 
ATOM   9250  C CG1 . ILE B 1 434 ? 119.573 103.315 69.859  1.00 73.38  ? 454 ILE B CG1 1 
ATOM   9251  C CG2 . ILE B 1 434 ? 119.239 105.804 69.930  1.00 72.30  ? 454 ILE B CG2 1 
ATOM   9252  C CD1 . ILE B 1 434 ? 120.115 103.128 71.252  1.00 74.41  ? 454 ILE B CD1 1 
ATOM   9253  N N   . LEU B 1 435 ? 116.059 106.297 71.144  1.00 66.36  ? 455 LEU B N   1 
ATOM   9254  C CA  . LEU B 1 435 ? 115.038 107.305 70.922  1.00 63.20  ? 455 LEU B CA  1 
ATOM   9255  C C   . LEU B 1 435 ? 115.602 108.668 71.305  1.00 60.32  ? 455 LEU B C   1 
ATOM   9256  O O   . LEU B 1 435 ? 116.597 108.761 72.020  1.00 60.46  ? 455 LEU B O   1 
ATOM   9257  C CB  . LEU B 1 435 ? 113.796 106.967 71.754  1.00 64.19  ? 455 LEU B CB  1 
ATOM   9258  C CG  . LEU B 1 435 ? 114.011 106.885 73.266  1.00 65.37  ? 455 LEU B CG  1 
ATOM   9259  C CD1 . LEU B 1 435 ? 113.661 108.202 73.948  1.00 65.28  ? 455 LEU B CD1 1 
ATOM   9260  C CD2 . LEU B 1 435 ? 113.208 105.741 73.868  1.00 66.41  ? 455 LEU B CD2 1 
ATOM   9261  N N   . PHE B 1 436 ? 114.935 109.723 70.830  1.00 58.31  ? 456 PHE B N   1 
ATOM   9262  C CA  . PHE B 1 436 ? 115.328 111.087 71.135  1.00 56.62  ? 456 PHE B CA  1 
ATOM   9263  C C   . PHE B 1 436 ? 114.230 111.773 71.942  1.00 58.12  ? 456 PHE B C   1 
ATOM   9264  O O   . PHE B 1 436 ? 113.051 111.671 71.613  1.00 59.56  ? 456 PHE B O   1 
ATOM   9265  C CB  . PHE B 1 436 ? 115.619 111.858 69.847  1.00 54.38  ? 456 PHE B CB  1 
ATOM   9266  C CG  . PHE B 1 436 ? 116.825 111.374 69.086  1.00 51.79  ? 456 PHE B CG  1 
ATOM   9267  C CD1 . PHE B 1 436 ? 118.087 111.397 69.657  1.00 51.39  ? 456 PHE B CD1 1 
ATOM   9268  C CD2 . PHE B 1 436 ? 116.693 110.886 67.798  1.00 51.15  ? 456 PHE B CD2 1 
ATOM   9269  C CE1 . PHE B 1 436 ? 119.194 110.956 68.946  1.00 51.72  ? 456 PHE B CE1 1 
ATOM   9270  C CE2 . PHE B 1 436 ? 117.797 110.441 67.090  1.00 51.45  ? 456 PHE B CE2 1 
ATOM   9271  C CZ  . PHE B 1 436 ? 119.047 110.470 67.666  1.00 51.65  ? 456 PHE B CZ  1 
ATOM   9272  N N   . ASP B 1 437 ? 114.642 112.522 72.967  1.00 59.06  ? 457 ASP B N   1 
ATOM   9273  C CA  . ASP B 1 437 ? 113.719 113.240 73.828  1.00 61.31  ? 457 ASP B CA  1 
ATOM   9274  C C   . ASP B 1 437 ? 113.254 114.502 73.101  1.00 62.41  ? 457 ASP B C   1 
ATOM   9275  O O   . ASP B 1 437 ? 113.533 114.685 71.914  1.00 62.99  ? 457 ASP B O   1 
ATOM   9276  C CB  . ASP B 1 437 ? 114.376 113.563 75.176  1.00 63.58  ? 457 ASP B CB  1 
ATOM   9277  C CG  . ASP B 1 437 ? 115.110 112.396 75.817  1.00 66.47  ? 457 ASP B CG  1 
ATOM   9278  O OD1 . ASP B 1 437 ? 115.167 111.318 75.188  1.00 67.58  ? 457 ASP B OD1 1 
ATOM   9279  O OD2 . ASP B 1 437 ? 115.612 112.576 76.949  1.00 67.70  ? 457 ASP B OD2 1 
ATOM   9280  N N   . GLU B 1 438 ? 112.565 115.390 73.829  1.00 63.37  ? 458 GLU B N   1 
ATOM   9281  C CA  . GLU B 1 438 ? 112.176 116.686 73.295  1.00 64.74  ? 458 GLU B CA  1 
ATOM   9282  C C   . GLU B 1 438 ? 113.409 117.557 73.049  1.00 61.99  ? 458 GLU B C   1 
ATOM   9283  O O   . GLU B 1 438 ? 113.377 118.423 72.178  1.00 61.41  ? 458 GLU B O   1 
ATOM   9284  C CB  . GLU B 1 438 ? 111.181 117.397 74.219  1.00 68.15  ? 458 GLU B CB  1 
ATOM   9285  C CG  . GLU B 1 438 ? 111.754 117.841 75.558  1.00 70.57  ? 458 GLU B CG  1 
ATOM   9286  C CD  . GLU B 1 438 ? 111.939 116.742 76.589  1.00 72.71  ? 458 GLU B CD  1 
ATOM   9287  O OE1 . GLU B 1 438 ? 111.656 115.571 76.268  1.00 73.49  ? 458 GLU B OE1 1 
ATOM   9288  O OE2 . GLU B 1 438 ? 112.352 117.063 77.722  1.00 73.80  ? 458 GLU B OE2 1 
ATOM   9289  N N   . ASN B 1 439 ? 114.487 117.325 73.810  1.00 58.51  ? 459 ASN B N   1 
ATOM   9290  C CA  . ASN B 1 439 ? 115.701 118.117 73.691  1.00 56.01  ? 459 ASN B CA  1 
ATOM   9291  C C   . ASN B 1 439 ? 116.716 117.455 72.760  1.00 53.57  ? 459 ASN B C   1 
ATOM   9292  O O   . ASN B 1 439 ? 117.835 117.951 72.629  1.00 54.94  ? 459 ASN B O   1 
ATOM   9293  C CB  . ASN B 1 439 ? 116.343 118.356 75.056  1.00 56.35  ? 459 ASN B CB  1 
ATOM   9294  C CG  . ASN B 1 439 ? 115.402 119.047 76.019  1.00 57.37  ? 459 ASN B CG  1 
ATOM   9295  O OD1 . ASN B 1 439 ? 114.894 120.127 75.724  1.00 58.26  ? 459 ASN B OD1 1 
ATOM   9296  N ND2 . ASN B 1 439 ? 115.157 118.433 77.166  1.00 57.72  ? 459 ASN B ND2 1 
ATOM   9297  N N   . GLY B 1 440 ? 116.335 116.352 72.106  1.00 49.88  ? 460 GLY B N   1 
ATOM   9298  C CA  . GLY B 1 440 ? 117.201 115.701 71.136  1.00 47.24  ? 460 GLY B CA  1 
ATOM   9299  C C   . GLY B 1 440 ? 118.278 114.827 71.778  1.00 45.56  ? 460 GLY B C   1 
ATOM   9300  O O   . GLY B 1 440 ? 119.129 114.291 71.072  1.00 45.72  ? 460 GLY B O   1 
ATOM   9301  N N   . ASP B 1 441 ? 118.227 114.649 73.103  1.00 44.20  ? 461 ASP B N   1 
ATOM   9302  C CA  . ASP B 1 441 ? 119.171 113.785 73.793  1.00 43.59  ? 461 ASP B CA  1 
ATOM   9303  C C   . ASP B 1 441 ? 118.735 112.330 73.637  1.00 43.48  ? 461 ASP B C   1 
ATOM   9304  O O   . ASP B 1 441 ? 117.793 112.034 72.907  1.00 43.92  ? 461 ASP B O   1 
ATOM   9305  C CB  . ASP B 1 441 ? 119.276 114.196 75.259  1.00 43.56  ? 461 ASP B CB  1 
ATOM   9306  C CG  . ASP B 1 441 ? 119.638 115.657 75.447  1.00 43.83  ? 461 ASP B CG  1 
ATOM   9307  O OD1 . ASP B 1 441 ? 119.899 116.356 74.445  1.00 43.48  ? 461 ASP B OD1 1 
ATOM   9308  O OD2 . ASP B 1 441 ? 119.716 116.069 76.606  1.00 44.14  ? 461 ASP B OD2 1 
ATOM   9309  N N   . SER B 1 442 ? 119.432 111.423 74.327  1.00 43.50  ? 462 SER B N   1 
ATOM   9310  C CA  . SER B 1 442 ? 119.084 110.012 74.314  1.00 43.97  ? 462 SER B CA  1 
ATOM   9311  C C   . SER B 1 442 ? 119.394 109.416 75.683  1.00 45.20  ? 462 SER B C   1 
ATOM   9312  O O   . SER B 1 442 ? 120.329 109.861 76.348  1.00 45.23  ? 462 SER B O   1 
ATOM   9313  C CB  . SER B 1 442 ? 119.820 109.294 73.211  1.00 43.47  ? 462 SER B CB  1 
ATOM   9314  O OG  . SER B 1 442 ? 119.495 107.915 73.174  1.00 43.44  ? 462 SER B OG  1 
ATOM   9315  N N   . PRO B 1 443 ? 118.624 108.412 76.158  1.00 47.42  ? 463 PRO B N   1 
ATOM   9316  C CA  . PRO B 1 443 ? 118.904 107.792 77.451  1.00 47.85  ? 463 PRO B CA  1 
ATOM   9317  C C   . PRO B 1 443 ? 120.218 107.017 77.415  1.00 46.03  ? 463 PRO B C   1 
ATOM   9318  O O   . PRO B 1 443 ? 120.582 106.451 76.386  1.00 45.28  ? 463 PRO B O   1 
ATOM   9319  C CB  . PRO B 1 443 ? 117.703 106.865 77.697  1.00 49.32  ? 463 PRO B CB  1 
ATOM   9320  C CG  . PRO B 1 443 ? 117.144 106.586 76.314  1.00 49.56  ? 463 PRO B CG  1 
ATOM   9321  C CD  . PRO B 1 443 ? 117.451 107.823 75.494  1.00 49.06  ? 463 PRO B CD  1 
ATOM   9322  N N   . GLY B 1 444 ? 120.926 107.027 78.546  1.00 44.70  ? 464 GLY B N   1 
ATOM   9323  C CA  . GLY B 1 444 ? 122.174 106.300 78.684  1.00 43.99  ? 464 GLY B CA  1 
ATOM   9324  C C   . GLY B 1 444 ? 122.571 106.160 80.149  1.00 43.18  ? 464 GLY B C   1 
ATOM   9325  O O   . GLY B 1 444 ? 122.058 106.873 81.007  1.00 42.95  ? 464 GLY B O   1 
ATOM   9326  N N   . ARG B 1 445 ? 123.485 105.225 80.412  1.00 41.47  ? 465 ARG B N   1 
ATOM   9327  C CA  . ARG B 1 445 ? 123.914 104.903 81.762  1.00 40.22  ? 465 ARG B CA  1 
ATOM   9328  C C   . ARG B 1 445 ? 125.436 104.914 81.800  1.00 37.52  ? 465 ARG B C   1 
ATOM   9329  O O   . ARG B 1 445 ? 126.090 104.807 80.766  1.00 38.18  ? 465 ARG B O   1 
ATOM   9330  C CB  . ARG B 1 445 ? 123.348 103.550 82.200  1.00 42.40  ? 465 ARG B CB  1 
ATOM   9331  C CG  . ARG B 1 445 ? 123.194 102.553 81.062  1.00 44.88  ? 465 ARG B CG  1 
ATOM   9332  C CD  . ARG B 1 445 ? 122.746 101.188 81.541  1.00 47.95  ? 465 ARG B CD  1 
ATOM   9333  N NE  . ARG B 1 445 ? 122.151 100.396 80.471  1.00 51.73  ? 465 ARG B NE  1 
ATOM   9334  C CZ  . ARG B 1 445 ? 120.983 100.648 79.884  1.00 55.74  ? 465 ARG B CZ  1 
ATOM   9335  N NH1 . ARG B 1 445 ? 120.215 101.642 80.302  1.00 56.31  ? 465 ARG B NH1 1 
ATOM   9336  N NH2 . ARG B 1 445 ? 120.574 99.886  78.882  1.00 56.81  ? 465 ARG B NH2 1 
ATOM   9337  N N   . TYR B 1 446 ? 125.983 105.039 83.011  1.00 34.78  ? 466 TYR B N   1 
ATOM   9338  C CA  . TYR B 1 446 ? 127.412 105.199 83.199  1.00 33.09  ? 466 TYR B CA  1 
ATOM   9339  C C   . TYR B 1 446 ? 127.990 103.975 83.897  1.00 32.12  ? 466 TYR B C   1 
ATOM   9340  O O   . TYR B 1 446 ? 127.292 103.286 84.634  1.00 32.81  ? 466 TYR B O   1 
ATOM   9341  C CB  . TYR B 1 446 ? 127.689 106.477 83.988  1.00 33.27  ? 466 TYR B CB  1 
ATOM   9342  C CG  . TYR B 1 446 ? 127.222 107.721 83.280  1.00 34.19  ? 466 TYR B CG  1 
ATOM   9343  C CD1 . TYR B 1 446 ? 127.974 108.289 82.268  1.00 35.21  ? 466 TYR B CD1 1 
ATOM   9344  C CD2 . TYR B 1 446 ? 126.003 108.299 83.583  1.00 34.64  ? 466 TYR B CD2 1 
ATOM   9345  C CE1 . TYR B 1 446 ? 127.545 109.422 81.598  1.00 35.78  ? 466 TYR B CE1 1 
ATOM   9346  C CE2 . TYR B 1 446 ? 125.560 109.436 82.929  1.00 35.61  ? 466 TYR B CE2 1 
ATOM   9347  C CZ  . TYR B 1 446 ? 126.328 109.994 81.923  1.00 36.11  ? 466 TYR B CZ  1 
ATOM   9348  O OH  . TYR B 1 446 ? 125.906 111.116 81.252  1.00 36.48  ? 466 TYR B OH  1 
ATOM   9349  N N   . GLU B 1 447 ? 129.268 103.713 83.613  1.00 31.30  ? 467 GLU B N   1 
ATOM   9350  C CA  . GLU B 1 447 ? 130.044 102.671 84.260  1.00 30.71  ? 467 GLU B CA  1 
ATOM   9351  C C   . GLU B 1 447 ? 131.185 103.341 85.008  1.00 29.62  ? 467 GLU B C   1 
ATOM   9352  O O   . GLU B 1 447 ? 131.953 104.085 84.414  1.00 30.41  ? 467 GLU B O   1 
ATOM   9353  C CB  . GLU B 1 447 ? 130.599 101.690 83.227  1.00 31.78  ? 467 GLU B CB  1 
ATOM   9354  C CG  . GLU B 1 447 ? 129.685 100.512 82.958  1.00 33.98  ? 467 GLU B CG  1 
ATOM   9355  C CD  . GLU B 1 447 ? 130.067 99.675  81.747  1.00 36.27  ? 467 GLU B CD  1 
ATOM   9356  O OE1 . GLU B 1 447 ? 131.201 99.835  81.240  1.00 36.92  ? 467 GLU B OE1 1 
ATOM   9357  O OE2 . GLU B 1 447 ? 129.221 98.874  81.300  1.00 37.15  ? 467 GLU B OE2 1 
ATOM   9358  N N   . ILE B 1 448 ? 131.305 103.056 86.301  1.00 28.92  ? 468 ILE B N   1 
ATOM   9359  C CA  . ILE B 1 448 ? 132.392 103.607 87.088  1.00 28.28  ? 468 ILE B CA  1 
ATOM   9360  C C   . ILE B 1 448 ? 133.583 102.665 86.968  1.00 28.46  ? 468 ILE B C   1 
ATOM   9361  O O   . ILE B 1 448 ? 133.447 101.463 87.179  1.00 29.28  ? 468 ILE B O   1 
ATOM   9362  C CB  . ILE B 1 448 ? 131.961 103.816 88.550  1.00 28.08  ? 468 ILE B CB  1 
ATOM   9363  C CG1 . ILE B 1 448 ? 130.612 104.533 88.645  1.00 28.13  ? 468 ILE B CG1 1 
ATOM   9364  C CG2 . ILE B 1 448 ? 133.046 104.541 89.328  1.00 28.21  ? 468 ILE B CG2 1 
ATOM   9365  C CD1 . ILE B 1 448 ? 130.550 105.828 87.865  1.00 28.37  ? 468 ILE B CD1 1 
ATOM   9366  N N   . MET B 1 449 ? 134.736 103.225 86.596  1.00 28.36  ? 469 MET B N   1 
ATOM   9367  C CA  . MET B 1 449 ? 135.930 102.431 86.377  1.00 28.53  ? 469 MET B CA  1 
ATOM   9368  C C   . MET B 1 449 ? 137.028 102.922 87.307  1.00 29.27  ? 469 MET B C   1 
ATOM   9369  O O   . MET B 1 449 ? 137.031 104.083 87.699  1.00 29.29  ? 469 MET B O   1 
ATOM   9370  C CB  . MET B 1 449 ? 136.404 102.549 84.929  1.00 28.19  ? 469 MET B CB  1 
ATOM   9371  C CG  . MET B 1 449 ? 135.291 102.311 83.944  1.00 28.07  ? 469 MET B CG  1 
ATOM   9372  S SD  . MET B 1 449 ? 135.869 101.472 82.459  1.00 28.96  ? 469 MET B SD  1 
ATOM   9373  C CE  . MET B 1 449 ? 135.918 99.774  83.032  1.00 29.23  ? 469 MET B CE  1 
ATOM   9374  N N   . ASN B 1 450 ? 137.952 102.018 87.640  1.00 30.67  ? 470 ASN B N   1 
ATOM   9375  C CA  . ASN B 1 450 ? 139.062 102.334 88.519  1.00 32.13  ? 470 ASN B CA  1 
ATOM   9376  C C   . ASN B 1 450 ? 140.342 101.808 87.882  1.00 33.36  ? 470 ASN B C   1 
ATOM   9377  O O   . ASN B 1 450 ? 140.365 100.690 87.368  1.00 34.15  ? 470 ASN B O   1 
ATOM   9378  C CB  . ASN B 1 450 ? 138.844 101.764 89.921  1.00 33.01  ? 470 ASN B CB  1 
ATOM   9379  C CG  . ASN B 1 450 ? 139.953 102.129 90.886  1.00 34.11  ? 470 ASN B CG  1 
ATOM   9380  O OD1 . ASN B 1 450 ? 140.459 103.250 90.875  1.00 34.40  ? 470 ASN B OD1 1 
ATOM   9381  N ND2 . ASN B 1 450 ? 140.354 101.179 91.715  1.00 35.03  ? 470 ASN B ND2 1 
ATOM   9382  N N   . PHE B 1 451 ? 141.392 102.633 87.920  1.00 35.13  ? 471 PHE B N   1 
ATOM   9383  C CA  . PHE B 1 451 ? 142.662 102.291 87.308  1.00 36.91  ? 471 PHE B CA  1 
ATOM   9384  C C   . PHE B 1 451 ? 143.533 101.598 88.349  1.00 41.15  ? 471 PHE B C   1 
ATOM   9385  O O   . PHE B 1 451 ? 143.945 102.216 89.327  1.00 41.74  ? 471 PHE B O   1 
ATOM   9386  C CB  . PHE B 1 451 ? 143.329 103.545 86.739  1.00 35.67  ? 471 PHE B CB  1 
ATOM   9387  C CG  . PHE B 1 451 ? 144.439 103.272 85.758  1.00 34.38  ? 471 PHE B CG  1 
ATOM   9388  C CD1 . PHE B 1 451 ? 144.251 102.401 84.700  1.00 34.51  ? 471 PHE B CD1 1 
ATOM   9389  C CD2 . PHE B 1 451 ? 145.667 103.896 85.880  1.00 34.24  ? 471 PHE B CD2 1 
ATOM   9390  C CE1 . PHE B 1 451 ? 145.262 102.156 83.787  1.00 34.83  ? 471 PHE B CE1 1 
ATOM   9391  C CE2 . PHE B 1 451 ? 146.684 103.647 84.972  1.00 34.53  ? 471 PHE B CE2 1 
ATOM   9392  C CZ  . PHE B 1 451 ? 146.478 102.780 83.925  1.00 34.71  ? 471 PHE B CZ  1 
ATOM   9393  N N   . LYS B 1 452 ? 143.801 100.306 88.136  1.00 46.26  ? 472 LYS B N   1 
ATOM   9394  C CA  . LYS B 1 452 ? 144.431 99.483  89.154  1.00 51.82  ? 472 LYS B CA  1 
ATOM   9395  C C   . LYS B 1 452 ? 145.673 98.804  88.588  1.00 57.45  ? 472 LYS B C   1 
ATOM   9396  O O   . LYS B 1 452 ? 145.843 98.714  87.373  1.00 58.58  ? 472 LYS B O   1 
ATOM   9397  C CB  . LYS B 1 452 ? 143.434 98.447  89.677  1.00 53.79  ? 472 LYS B CB  1 
ATOM   9398  C CG  . LYS B 1 452 ? 142.448 98.953  90.722  1.00 55.31  ? 472 LYS B CG  1 
ATOM   9399  C CD  . LYS B 1 452 ? 141.253 98.036  90.961  1.00 56.77  ? 472 LYS B CD  1 
ATOM   9400  C CE  . LYS B 1 452 ? 141.600 96.575  91.175  1.00 58.64  ? 472 LYS B CE  1 
ATOM   9401  N NZ  . LYS B 1 452 ? 142.514 96.370  92.324  1.00 59.45  ? 472 LYS B NZ  1 
ATOM   9402  N N   . GLU B 1 453 ? 146.533 98.341  89.503  1.00 65.09  ? 473 GLU B N   1 
ATOM   9403  C CA  . GLU B 1 453 ? 147.699 97.541  89.167  1.00 72.47  ? 473 GLU B CA  1 
ATOM   9404  C C   . GLU B 1 453 ? 147.427 96.097  89.576  1.00 75.87  ? 473 GLU B C   1 
ATOM   9405  O O   . GLU B 1 453 ? 147.219 95.824  90.755  1.00 77.14  ? 473 GLU B O   1 
ATOM   9406  C CB  . GLU B 1 453 ? 148.949 98.091  89.863  1.00 76.85  ? 473 GLU B CB  1 
ATOM   9407  C CG  . GLU B 1 453 ? 150.133 97.137  89.831  1.00 81.55  ? 473 GLU B CG  1 
ATOM   9408  C CD  . GLU B 1 453 ? 151.503 97.734  90.095  1.00 85.92  ? 473 GLU B CD  1 
ATOM   9409  O OE1 . GLU B 1 453 ? 151.591 98.964  90.281  1.00 86.96  ? 473 GLU B OE1 1 
ATOM   9410  O OE2 . GLU B 1 453 ? 152.482 96.960  90.098  1.00 88.26  ? 473 GLU B OE2 1 
ATOM   9411  N N   . MET B 1 454 ? 147.462 95.183  88.597  1.00 79.20  ? 474 MET B N   1 
ATOM   9412  C CA  . MET B 1 454 ? 147.156 93.784  88.852  1.00 83.88  ? 474 MET B CA  1 
ATOM   9413  C C   . MET B 1 454 ? 148.452 93.001  89.041  1.00 90.67  ? 474 MET B C   1 
ATOM   9414  O O   . MET B 1 454 ? 148.674 92.419  90.102  1.00 92.49  ? 474 MET B O   1 
ATOM   9415  C CB  . MET B 1 454 ? 146.335 93.178  87.707  1.00 83.13  ? 474 MET B CB  1 
ATOM   9416  C CG  . MET B 1 454 ? 145.227 94.094  87.204  1.00 82.08  ? 474 MET B CG  1 
ATOM   9417  S SD  . MET B 1 454 ? 144.483 95.131  88.495  1.00 79.48  ? 474 MET B SD  1 
ATOM   9418  C CE  . MET B 1 454 ? 143.504 93.938  89.409  1.00 80.43  ? 474 MET B CE  1 
ATOM   9419  N N   . GLY B 1 455 ? 149.301 93.001  88.006  1.00 97.24  ? 475 GLY B N   1 
ATOM   9420  C CA  . GLY B 1 455 ? 150.563 92.280  88.037  1.00 101.93 ? 475 GLY B CA  1 
ATOM   9421  C C   . GLY B 1 455 ? 151.744 93.226  88.228  1.00 106.70 ? 475 GLY B C   1 
ATOM   9422  O O   . GLY B 1 455 ? 151.566 94.380  88.613  1.00 105.62 ? 475 GLY B O   1 
ATOM   9423  N N   . LYS B 1 456 ? 152.952 92.722  87.957  1.00 112.95 ? 476 LYS B N   1 
ATOM   9424  C CA  . LYS B 1 456 ? 154.135 93.564  87.944  1.00 118.21 ? 476 LYS B CA  1 
ATOM   9425  C C   . LYS B 1 456 ? 154.218 94.248  86.582  1.00 116.68 ? 476 LYS B C   1 
ATOM   9426  O O   . LYS B 1 456 ? 154.229 93.580  85.550  1.00 115.17 ? 476 LYS B O   1 
ATOM   9427  C CB  . LYS B 1 456 ? 155.396 92.751  88.259  1.00 123.12 ? 476 LYS B CB  1 
ATOM   9428  C CG  . LYS B 1 456 ? 156.690 93.556  88.345  1.00 126.52 ? 476 LYS B CG  1 
ATOM   9429  C CD  . LYS B 1 456 ? 156.577 94.867  89.113  1.00 128.75 ? 476 LYS B CD  1 
ATOM   9430  C CE  . LYS B 1 456 ? 156.043 94.714  90.523  1.00 129.81 ? 476 LYS B CE  1 
ATOM   9431  N NZ  . LYS B 1 456 ? 155.716 96.027  91.129  1.00 129.65 ? 476 LYS B NZ  1 
ATOM   9432  N N   . ASP B 1 457 ? 154.264 95.585  86.608  1.00 115.36 ? 477 ASP B N   1 
ATOM   9433  C CA  . ASP B 1 457 ? 154.284 96.404  85.406  1.00 114.65 ? 477 ASP B CA  1 
ATOM   9434  C C   . ASP B 1 457 ? 153.084 96.045  84.530  1.00 106.98 ? 477 ASP B C   1 
ATOM   9435  O O   . ASP B 1 457 ? 153.232 95.735  83.349  1.00 107.26 ? 477 ASP B O   1 
ATOM   9436  C CB  . ASP B 1 457 ? 155.612 96.264  84.657  1.00 118.85 ? 477 ASP B CB  1 
ATOM   9437  C CG  . ASP B 1 457 ? 155.791 97.272  83.534  1.00 122.93 ? 477 ASP B CG  1 
ATOM   9438  O OD1 . ASP B 1 457 ? 154.913 98.147  83.371  1.00 122.84 ? 477 ASP B OD1 1 
ATOM   9439  O OD2 . ASP B 1 457 ? 156.820 97.184  82.833  1.00 125.43 ? 477 ASP B OD2 1 
ATOM   9440  N N   . TYR B 1 458 ? 151.890 96.111  85.129  1.00 97.51  ? 478 TYR B N   1 
ATOM   9441  C CA  . TYR B 1 458 ? 150.652 95.807  84.433  1.00 90.71  ? 478 TYR B CA  1 
ATOM   9442  C C   . TYR B 1 458 ? 149.525 96.595  85.088  1.00 80.95  ? 478 TYR B C   1 
ATOM   9443  O O   . TYR B 1 458 ? 149.167 96.332  86.234  1.00 81.33  ? 478 TYR B O   1 
ATOM   9444  C CB  . TYR B 1 458 ? 150.384 94.299  84.449  1.00 93.53  ? 478 TYR B CB  1 
ATOM   9445  C CG  . TYR B 1 458 ? 149.182 93.850  83.653  1.00 96.93  ? 478 TYR B CG  1 
ATOM   9446  C CD1 . TYR B 1 458 ? 147.891 94.163  84.049  1.00 97.82  ? 478 TYR B CD1 1 
ATOM   9447  C CD2 . TYR B 1 458 ? 149.333 93.086  82.503  1.00 100.80 ? 478 TYR B CD2 1 
ATOM   9448  C CE1 . TYR B 1 458 ? 146.787 93.749  83.322  1.00 100.77 ? 478 TYR B CE1 1 
ATOM   9449  C CE2 . TYR B 1 458 ? 148.240 92.664  81.764  1.00 102.86 ? 478 TYR B CE2 1 
ATOM   9450  C CZ  . TYR B 1 458 ? 146.961 92.994  82.175  1.00 103.70 ? 478 TYR B CZ  1 
ATOM   9451  O OH  . TYR B 1 458 ? 145.870 92.578  81.450  1.00 105.14 ? 478 TYR B OH  1 
ATOM   9452  N N   . PHE B 1 459 ? 148.991 97.571  84.348  1.00 71.14  ? 479 PHE B N   1 
ATOM   9453  C CA  . PHE B 1 459 ? 147.910 98.408  84.829  1.00 65.36  ? 479 PHE B CA  1 
ATOM   9454  C C   . PHE B 1 459 ? 146.719 98.291  83.884  1.00 59.75  ? 479 PHE B C   1 
ATOM   9455  O O   . PHE B 1 459 ? 146.888 98.126  82.676  1.00 61.51  ? 479 PHE B O   1 
ATOM   9456  C CB  . PHE B 1 459 ? 148.376 99.857  84.924  1.00 67.32  ? 479 PHE B CB  1 
ATOM   9457  C CG  . PHE B 1 459 ? 149.542 100.086 85.847  1.00 70.32  ? 479 PHE B CG  1 
ATOM   9458  C CD1 . PHE B 1 459 ? 150.826 99.686  85.508  1.00 71.63  ? 479 PHE B CD1 1 
ATOM   9459  C CD2 . PHE B 1 459 ? 149.350 100.742 87.051  1.00 71.75  ? 479 PHE B CD2 1 
ATOM   9460  C CE1 . PHE B 1 459 ? 151.888 99.917  86.368  1.00 72.14  ? 479 PHE B CE1 1 
ATOM   9461  C CE2 . PHE B 1 459 ? 150.416 100.991 87.902  1.00 72.49  ? 479 PHE B CE2 1 
ATOM   9462  C CZ  . PHE B 1 459 ? 151.681 100.568 87.563  1.00 73.02  ? 479 PHE B CZ  1 
ATOM   9463  N N   . ASP B 1 460 ? 145.514 98.396  84.447  1.00 53.22  ? 480 ASP B N   1 
ATOM   9464  C CA  . ASP B 1 460 ? 144.310 98.165  83.669  1.00 48.77  ? 480 ASP B CA  1 
ATOM   9465  C C   . ASP B 1 460 ? 143.136 98.899  84.302  1.00 43.54  ? 480 ASP B C   1 
ATOM   9466  O O   . ASP B 1 460 ? 143.149 99.177  85.500  1.00 43.50  ? 480 ASP B O   1 
ATOM   9467  C CB  . ASP B 1 460 ? 144.006 96.669  83.562  1.00 51.24  ? 480 ASP B CB  1 
ATOM   9468  C CG  . ASP B 1 460 ? 143.150 96.319  82.359  1.00 54.48  ? 480 ASP B CG  1 
ATOM   9469  O OD1 . ASP B 1 460 ? 143.084 97.141  81.437  1.00 55.52  ? 480 ASP B OD1 1 
ATOM   9470  O OD2 . ASP B 1 460 ? 142.583 95.208  82.338  1.00 56.48  ? 480 ASP B OD2 1 
ATOM   9471  N N   . TYR B 1 461 ? 142.128 99.209  83.479  1.00 39.58  ? 481 TYR B N   1 
ATOM   9472  C CA  . TYR B 1 461 ? 140.881 99.765  83.974  1.00 36.77  ? 481 TYR B CA  1 
ATOM   9473  C C   . TYR B 1 461 ? 139.941 98.630  84.359  1.00 37.14  ? 481 TYR B C   1 
ATOM   9474  O O   . TYR B 1 461 ? 139.750 97.691  83.587  1.00 37.25  ? 481 TYR B O   1 
ATOM   9475  C CB  . TYR B 1 461 ? 140.206 100.657 82.931  1.00 34.24  ? 481 TYR B CB  1 
ATOM   9476  C CG  . TYR B 1 461 ? 140.938 101.938 82.642  1.00 31.84  ? 481 TYR B CG  1 
ATOM   9477  C CD1 . TYR B 1 461 ? 141.931 101.989 81.680  1.00 30.56  ? 481 TYR B CD1 1 
ATOM   9478  C CD2 . TYR B 1 461 ? 140.669 103.088 83.368  1.00 31.09  ? 481 TYR B CD2 1 
ATOM   9479  C CE1 . TYR B 1 461 ? 142.614 103.163 81.415  1.00 30.05  ? 481 TYR B CE1 1 
ATOM   9480  C CE2 . TYR B 1 461 ? 141.351 104.268 83.126  1.00 30.53  ? 481 TYR B CE2 1 
ATOM   9481  C CZ  . TYR B 1 461 ? 142.320 104.306 82.139  1.00 29.81  ? 481 TYR B CZ  1 
ATOM   9482  O OH  . TYR B 1 461 ? 142.980 105.481 81.896  1.00 29.01  ? 481 TYR B OH  1 
ATOM   9483  N N   . ILE B 1 462 ? 139.355 98.740  85.556  1.00 37.33  ? 482 ILE B N   1 
ATOM   9484  C CA  . ILE B 1 462 ? 138.418 97.747  86.046  1.00 37.78  ? 482 ILE B CA  1 
ATOM   9485  C C   . ILE B 1 462 ? 137.079 98.419  86.329  1.00 37.31  ? 482 ILE B C   1 
ATOM   9486  O O   . ILE B 1 462 ? 137.026 99.431  87.019  1.00 36.69  ? 482 ILE B O   1 
ATOM   9487  C CB  . ILE B 1 462 ? 138.994 97.033  87.283  1.00 39.23  ? 482 ILE B CB  1 
ATOM   9488  C CG1 . ILE B 1 462 ? 140.112 96.075  86.862  1.00 40.53  ? 482 ILE B CG1 1 
ATOM   9489  C CG2 . ILE B 1 462 ? 137.901 96.324  88.068  1.00 39.96  ? 482 ILE B CG2 1 
ATOM   9490  C CD1 . ILE B 1 462 ? 140.628 95.179  87.957  1.00 41.82  ? 482 ILE B CD1 1 
ATOM   9491  N N   . ASN B 1 463 ? 136.003 97.814  85.814  1.00 37.40  ? 483 ASN B N   1 
ATOM   9492  C CA  . ASN B 1 463 ? 134.653 98.270  86.095  1.00 37.61  ? 483 ASN B CA  1 
ATOM   9493  C C   . ASN B 1 463 ? 134.320 97.955  87.549  1.00 37.06  ? 483 ASN B C   1 
ATOM   9494  O O   . ASN B 1 463 ? 134.201 96.791  87.915  1.00 37.63  ? 483 ASN B O   1 
ATOM   9495  C CB  . ASN B 1 463 ? 133.634 97.630  85.146  1.00 38.68  ? 483 ASN B CB  1 
ATOM   9496  C CG  . ASN B 1 463 ? 132.201 97.973  85.496  1.00 40.00  ? 483 ASN B CG  1 
ATOM   9497  O OD1 . ASN B 1 463 ? 131.355 97.091  85.608  1.00 41.13  ? 483 ASN B OD1 1 
ATOM   9498  N ND2 . ASN B 1 463 ? 131.928 99.250  85.710  1.00 40.42  ? 483 ASN B ND2 1 
ATOM   9499  N N   . VAL B 1 464 ? 134.142 99.004  88.359  1.00 36.40  ? 484 VAL B N   1 
ATOM   9500  C CA  . VAL B 1 464 ? 133.893 98.838  89.779  1.00 36.04  ? 484 VAL B CA  1 
ATOM   9501  C C   . VAL B 1 464 ? 132.504 99.358  90.140  1.00 36.56  ? 484 VAL B C   1 
ATOM   9502  O O   . VAL B 1 464 ? 132.195 99.490  91.317  1.00 38.15  ? 484 VAL B O   1 
ATOM   9503  C CB  . VAL B 1 464 ? 134.971 99.540  90.624  1.00 35.15  ? 484 VAL B CB  1 
ATOM   9504  C CG1 . VAL B 1 464 ? 136.359 99.002  90.316  1.00 34.96  ? 484 VAL B CG1 1 
ATOM   9505  C CG2 . VAL B 1 464 ? 134.930 101.054 90.468  1.00 35.17  ? 484 VAL B CG2 1 
ATOM   9506  N N   . GLY B 1 465 ? 131.665 99.649  89.145  1.00 36.40  ? 485 GLY B N   1 
ATOM   9507  C CA  . GLY B 1 465 ? 130.318 100.091 89.447  1.00 36.88  ? 485 GLY B CA  1 
ATOM   9508  C C   . GLY B 1 465 ? 129.544 100.518 88.208  1.00 36.57  ? 485 GLY B C   1 
ATOM   9509  O O   . GLY B 1 465 ? 129.962 100.276 87.076  1.00 37.16  ? 485 GLY B O   1 
ATOM   9510  N N   . SER B 1 466 ? 128.381 101.119 88.471  1.00 35.59  ? 486 SER B N   1 
ATOM   9511  C CA  . SER B 1 466 ? 127.486 101.596 87.436  1.00 35.22  ? 486 SER B CA  1 
ATOM   9512  C C   . SER B 1 466 ? 126.567 102.647 88.038  1.00 35.14  ? 486 SER B C   1 
ATOM   9513  O O   . SER B 1 466 ? 126.454 102.765 89.258  1.00 36.23  ? 486 SER B O   1 
ATOM   9514  C CB  . SER B 1 466 ? 126.696 100.469 86.820  1.00 36.03  ? 486 SER B CB  1 
ATOM   9515  O OG  . SER B 1 466 ? 125.865 99.850  87.788  1.00 36.57  ? 486 SER B OG  1 
ATOM   9516  N N   . TRP B 1 467 ? 125.925 103.409 87.152  1.00 35.79  ? 487 TRP B N   1 
ATOM   9517  C CA  . TRP B 1 467 ? 125.088 104.526 87.541  1.00 36.77  ? 487 TRP B CA  1 
ATOM   9518  C C   . TRP B 1 467 ? 123.979 104.671 86.508  1.00 40.38  ? 487 TRP B C   1 
ATOM   9519  O O   . TRP B 1 467 ? 124.264 104.810 85.326  1.00 41.32  ? 487 TRP B O   1 
ATOM   9520  C CB  . TRP B 1 467 ? 125.930 105.799 87.666  1.00 35.46  ? 487 TRP B CB  1 
ATOM   9521  C CG  . TRP B 1 467 ? 125.194 106.948 88.281  1.00 35.36  ? 487 TRP B CG  1 
ATOM   9522  C CD1 . TRP B 1 467 ? 125.299 107.382 89.569  1.00 35.80  ? 487 TRP B CD1 1 
ATOM   9523  C CD2 . TRP B 1 467 ? 124.248 107.824 87.639  1.00 35.75  ? 487 TRP B CD2 1 
ATOM   9524  N NE1 . TRP B 1 467 ? 124.477 108.457 89.777  1.00 35.98  ? 487 TRP B NE1 1 
ATOM   9525  C CE2 . TRP B 1 467 ? 123.820 108.752 88.612  1.00 35.91  ? 487 TRP B CE2 1 
ATOM   9526  C CE3 . TRP B 1 467 ? 123.715 107.915 86.348  1.00 36.00  ? 487 TRP B CE3 1 
ATOM   9527  C CZ2 . TRP B 1 467 ? 122.895 109.754 88.331  1.00 36.12  ? 487 TRP B CZ2 1 
ATOM   9528  C CZ3 . TRP B 1 467 ? 122.800 108.906 86.069  1.00 36.10  ? 487 TRP B CZ3 1 
ATOM   9529  C CH2 . TRP B 1 467 ? 122.394 109.810 87.050  1.00 36.22  ? 487 TRP B CH2 1 
ATOM   9530  N N   . ASP B 1 468 ? 122.724 104.631 86.959  1.00 45.65  ? 488 ASP B N   1 
ATOM   9531  C CA  . ASP B 1 468 ? 121.595 104.632 86.047  1.00 50.17  ? 488 ASP B CA  1 
ATOM   9532  C C   . ASP B 1 468 ? 120.403 105.322 86.705  1.00 52.67  ? 488 ASP B C   1 
ATOM   9533  O O   . ASP B 1 468 ? 119.861 104.831 87.695  1.00 53.30  ? 488 ASP B O   1 
ATOM   9534  C CB  . ASP B 1 468 ? 121.249 103.205 85.620  1.00 52.66  ? 488 ASP B CB  1 
ATOM   9535  C CG  . ASP B 1 468 ? 120.321 103.141 84.419  1.00 55.02  ? 488 ASP B CG  1 
ATOM   9536  O OD1 . ASP B 1 468 ? 119.938 104.216 83.915  1.00 55.29  ? 488 ASP B OD1 1 
ATOM   9537  O OD2 . ASP B 1 468 ? 119.998 102.015 83.988  1.00 56.42  ? 488 ASP B OD2 1 
ATOM   9538  N N   . ASN B 1 469 ? 120.027 106.481 86.149  1.00 55.83  ? 489 ASN B N   1 
ATOM   9539  C CA  . ASN B 1 469 ? 118.829 107.204 86.545  1.00 59.25  ? 489 ASN B CA  1 
ATOM   9540  C C   . ASN B 1 469 ? 118.841 107.485 88.046  1.00 59.56  ? 489 ASN B C   1 
ATOM   9541  O O   . ASN B 1 469 ? 117.828 107.310 88.719  1.00 61.27  ? 489 ASN B O   1 
ATOM   9542  C CB  . ASN B 1 469 ? 117.563 106.446 86.137  1.00 62.28  ? 489 ASN B CB  1 
ATOM   9543  C CG  . ASN B 1 469 ? 117.418 106.323 84.634  1.00 65.23  ? 489 ASN B CG  1 
ATOM   9544  O OD1 . ASN B 1 469 ? 117.486 107.325 83.924  1.00 66.27  ? 489 ASN B OD1 1 
ATOM   9545  N ND2 . ASN B 1 469 ? 117.188 105.114 84.141  1.00 66.04  ? 489 ASN B ND2 1 
ATOM   9546  N N   . GLY B 1 470 ? 120.003 107.890 88.570  1.00 59.03  ? 490 GLY B N   1 
ATOM   9547  C CA  . GLY B 1 470 ? 120.129 108.256 89.969  1.00 59.77  ? 490 GLY B CA  1 
ATOM   9548  C C   . GLY B 1 470 ? 120.690 107.134 90.839  1.00 60.37  ? 490 GLY B C   1 
ATOM   9549  O O   . GLY B 1 470 ? 121.173 107.404 91.934  1.00 60.37  ? 490 GLY B O   1 
ATOM   9550  N N   . GLU B 1 471 ? 120.597 105.880 90.378  1.00 61.53  ? 491 GLU B N   1 
ATOM   9551  C CA  . GLU B 1 471 ? 121.037 104.753 91.186  1.00 64.11  ? 491 GLU B CA  1 
ATOM   9552  C C   . GLU B 1 471 ? 122.537 104.544 90.990  1.00 61.06  ? 491 GLU B C   1 
ATOM   9553  O O   . GLU B 1 471 ? 122.969 104.295 89.870  1.00 60.97  ? 491 GLU B O   1 
ATOM   9554  C CB  . GLU B 1 471 ? 120.239 103.503 90.816  1.00 68.98  ? 491 GLU B CB  1 
ATOM   9555  C CG  . GLU B 1 471 ? 120.535 102.308 91.708  1.00 73.22  ? 491 GLU B CG  1 
ATOM   9556  C CD  . GLU B 1 471 ? 119.726 101.060 91.400  1.00 76.65  ? 491 GLU B CD  1 
ATOM   9557  O OE1 . GLU B 1 471 ? 118.876 101.111 90.486  1.00 77.74  ? 491 GLU B OE1 1 
ATOM   9558  O OE2 . GLU B 1 471 ? 119.944 100.037 92.080  1.00 78.57  ? 491 GLU B OE2 1 
ATOM   9559  N N   . LEU B 1 472 ? 123.318 104.666 92.072  1.00 58.80  ? 492 LEU B N   1 
ATOM   9560  C CA  . LEU B 1 472 ? 124.754 104.431 92.038  1.00 57.89  ? 492 LEU B CA  1 
ATOM   9561  C C   . LEU B 1 472 ? 125.035 103.091 92.707  1.00 60.06  ? 492 LEU B C   1 
ATOM   9562  O O   . LEU B 1 472 ? 124.940 102.982 93.926  1.00 61.88  ? 492 LEU B O   1 
ATOM   9563  C CB  . LEU B 1 472 ? 125.472 105.575 92.766  1.00 56.46  ? 492 LEU B CB  1 
ATOM   9564  C CG  . LEU B 1 472 ? 126.965 105.373 93.024  1.00 55.28  ? 492 LEU B CG  1 
ATOM   9565  C CD1 . LEU B 1 472 ? 127.755 105.403 91.726  1.00 55.40  ? 492 LEU B CD1 1 
ATOM   9566  C CD2 . LEU B 1 472 ? 127.502 106.418 93.988  1.00 54.39  ? 492 LEU B CD2 1 
ATOM   9567  N N   . LYS B 1 473 ? 125.364 102.077 91.898  1.00 62.61  ? 493 LYS B N   1 
ATOM   9568  C CA  . LYS B 1 473 ? 125.622 100.741 92.402  1.00 65.86  ? 493 LYS B CA  1 
ATOM   9569  C C   . LYS B 1 473 ? 127.092 100.429 92.154  1.00 66.21  ? 493 LYS B C   1 
ATOM   9570  O O   . LYS B 1 473 ? 127.502 100.271 91.010  1.00 67.49  ? 493 LYS B O   1 
ATOM   9571  C CB  . LYS B 1 473 ? 124.667 99.741  91.734  1.00 68.49  ? 493 LYS B CB  1 
ATOM   9572  C CG  . LYS B 1 473 ? 124.673 98.332  92.310  1.00 71.58  ? 493 LYS B CG  1 
ATOM   9573  C CD  . LYS B 1 473 ? 123.283 97.731  92.498  1.00 74.76  ? 493 LYS B CD  1 
ATOM   9574  C CE  . LYS B 1 473 ? 122.383 97.837  91.283  1.00 76.57  ? 493 LYS B CE  1 
ATOM   9575  N NZ  . LYS B 1 473 ? 123.004 97.224  90.086  1.00 77.83  ? 493 LYS B NZ  1 
ATOM   9576  N N   . MET B 1 474 ? 127.884 100.316 93.227  1.00 66.89  ? 494 MET B N   1 
ATOM   9577  C CA  . MET B 1 474 ? 129.329 100.274 93.081  1.00 67.53  ? 494 MET B CA  1 
ATOM   9578  C C   . MET B 1 474 ? 129.946 99.379  94.151  1.00 70.87  ? 494 MET B C   1 
ATOM   9579  O O   . MET B 1 474 ? 129.663 99.520  95.336  1.00 71.95  ? 494 MET B O   1 
ATOM   9580  C CB  . MET B 1 474 ? 129.904 101.690 93.177  1.00 66.23  ? 494 MET B CB  1 
ATOM   9581  C CG  . MET B 1 474 ? 131.383 101.749 93.516  1.00 64.88  ? 494 MET B CG  1 
ATOM   9582  S SD  . MET B 1 474 ? 132.115 103.360 93.122  1.00 62.46  ? 494 MET B SD  1 
ATOM   9583  C CE  . MET B 1 474 ? 131.143 104.425 94.186  1.00 63.21  ? 494 MET B CE  1 
ATOM   9584  N N   . ASP B 1 475 ? 130.794 98.459  93.691  1.00 75.88  ? 495 ASP B N   1 
ATOM   9585  C CA  . ASP B 1 475 ? 131.486 97.522  94.553  1.00 82.12  ? 495 ASP B CA  1 
ATOM   9586  C C   . ASP B 1 475 ? 132.632 98.251  95.248  1.00 84.70  ? 495 ASP B C   1 
ATOM   9587  O O   . ASP B 1 475 ? 133.345 99.021  94.612  1.00 84.79  ? 495 ASP B O   1 
ATOM   9588  C CB  . ASP B 1 475 ? 131.993 96.338  93.725  1.00 85.33  ? 495 ASP B CB  1 
ATOM   9589  C CG  . ASP B 1 475 ? 132.710 95.259  94.517  1.00 88.53  ? 495 ASP B CG  1 
ATOM   9590  O OD1 . ASP B 1 475 ? 132.831 95.406  95.748  1.00 90.15  ? 495 ASP B OD1 1 
ATOM   9591  O OD2 . ASP B 1 475 ? 133.138 94.271  93.892  1.00 90.08  ? 495 ASP B OD2 1 
ATOM   9592  N N   . ASP B 1 476 ? 132.811 97.987  96.549  1.00 89.70  ? 496 ASP B N   1 
ATOM   9593  C CA  . ASP B 1 476 ? 133.864 98.616  97.334  1.00 94.37  ? 496 ASP B CA  1 
ATOM   9594  C C   . ASP B 1 476 ? 134.941 97.599  97.720  1.00 101.16 ? 496 ASP B C   1 
ATOM   9595  O O   . ASP B 1 476 ? 135.782 97.886  98.571  1.00 102.99 ? 496 ASP B O   1 
ATOM   9596  C CB  . ASP B 1 476 ? 133.291 99.267  98.594  1.00 93.22  ? 496 ASP B CB  1 
ATOM   9597  C CG  . ASP B 1 476 ? 132.156 100.241 98.337  1.00 92.47  ? 496 ASP B CG  1 
ATOM   9598  O OD1 . ASP B 1 476 ? 131.833 100.464 97.159  1.00 91.73  ? 496 ASP B OD1 1 
ATOM   9599  O OD2 . ASP B 1 476 ? 131.601 100.762 99.321  1.00 92.69  ? 496 ASP B OD2 1 
ATOM   9600  N N   . ASP B 1 477 ? 134.924 96.418  97.089  1.00 107.22 ? 497 ASP B N   1 
ATOM   9601  C CA  . ASP B 1 477 ? 135.917 95.385  97.342  1.00 112.79 ? 497 ASP B CA  1 
ATOM   9602  C C   . ASP B 1 477 ? 137.037 95.490  96.308  1.00 113.02 ? 497 ASP B C   1 
ATOM   9603  O O   . ASP B 1 477 ? 138.210 95.428  96.666  1.00 112.92 ? 497 ASP B O   1 
ATOM   9604  C CB  . ASP B 1 477 ? 135.274 93.993  97.356  1.00 117.86 ? 497 ASP B CB  1 
ATOM   9605  C CG  . ASP B 1 477 ? 136.250 92.825  97.373  1.00 122.19 ? 497 ASP B CG  1 
ATOM   9606  O OD1 . ASP B 1 477 ? 137.099 92.762  96.458  1.00 123.57 ? 497 ASP B OD1 1 
ATOM   9607  O OD2 . ASP B 1 477 ? 136.136 91.965  98.281  1.00 123.08 ? 497 ASP B OD2 1 
ATOM   9608  N N   . GLU B 1 478 ? 136.670 95.615  95.025  1.00 112.79 ? 498 GLU B N   1 
ATOM   9609  C CA  . GLU B 1 478 ? 137.659 95.702  93.962  1.00 113.18 ? 498 GLU B CA  1 
ATOM   9610  C C   . GLU B 1 478 ? 138.499 96.965  94.118  1.00 108.04 ? 498 GLU B C   1 
ATOM   9611  O O   . GLU B 1 478 ? 139.714 96.925  93.940  1.00 106.78 ? 498 GLU B O   1 
ATOM   9612  C CB  . GLU B 1 478 ? 137.000 95.645  92.582  1.00 118.38 ? 498 GLU B CB  1 
ATOM   9613  C CG  . GLU B 1 478 ? 136.695 94.229  92.131  1.00 123.33 ? 498 GLU B CG  1 
ATOM   9614  C CD  . GLU B 1 478 ? 137.896 93.297  92.165  1.00 126.77 ? 498 GLU B CD  1 
ATOM   9615  O OE1 . GLU B 1 478 ? 138.795 93.455  91.310  1.00 126.99 ? 498 GLU B OE1 1 
ATOM   9616  O OE2 . GLU B 1 478 ? 137.943 92.437  93.069  1.00 127.51 ? 498 GLU B OE2 1 
ATOM   9617  N N   . VAL B 1 479 ? 137.841 98.081  94.446  1.00 105.40 ? 499 VAL B N   1 
ATOM   9618  C CA  . VAL B 1 479 ? 138.546 99.311  94.769  1.00 105.46 ? 499 VAL B CA  1 
ATOM   9619  C C   . VAL B 1 479 ? 138.856 99.301  96.264  1.00 109.55 ? 499 VAL B C   1 
ATOM   9620  O O   . VAL B 1 479 ? 137.972 99.049  97.078  1.00 108.69 ? 499 VAL B O   1 
ATOM   9621  C CB  . VAL B 1 479 ? 137.754 100.567 94.349  1.00 102.44 ? 499 VAL B CB  1 
ATOM   9622  C CG1 . VAL B 1 479 ? 136.314 100.548 94.843  1.00 103.03 ? 499 VAL B CG1 1 
ATOM   9623  C CG2 . VAL B 1 479 ? 138.447 101.845 94.796  1.00 100.23 ? 499 VAL B CG2 1 
ATOM   9624  N N   . TRP B 1 480 ? 140.122 99.570  96.607  1.00 115.07 ? 500 TRP B N   1 
ATOM   9625  C CA  . TRP B 1 480 ? 140.590 99.559  97.985  1.00 119.26 ? 500 TRP B CA  1 
ATOM   9626  C C   . TRP B 1 480 ? 140.328 98.202  98.632  1.00 127.20 ? 500 TRP B C   1 
ATOM   9627  O O   . TRP B 1 480 ? 139.509 98.094  99.546  1.00 126.87 ? 500 TRP B O   1 
ATOM   9628  C CB  . TRP B 1 480 ? 139.942 100.688 98.795  1.00 115.81 ? 500 TRP B CB  1 
ATOM   9629  C CG  . TRP B 1 480 ? 140.153 102.049 98.212  1.00 113.47 ? 500 TRP B CG  1 
ATOM   9630  C CD1 . TRP B 1 480 ? 141.324 102.584 97.759  1.00 112.89 ? 500 TRP B CD1 1 
ATOM   9631  C CD2 . TRP B 1 480 ? 139.156 103.069 98.047  1.00 109.81 ? 500 TRP B CD2 1 
ATOM   9632  N NE1 . TRP B 1 480 ? 141.122 103.862 97.313  1.00 112.01 ? 500 TRP B NE1 1 
ATOM   9633  C CE2 . TRP B 1 480 ? 139.802 104.187 97.478  1.00 109.02 ? 500 TRP B CE2 1 
ATOM   9634  C CE3 . TRP B 1 480 ? 137.786 103.142 98.318  1.00 106.58 ? 500 TRP B CE3 1 
ATOM   9635  C CZ2 . TRP B 1 480 ? 139.117 105.360 97.174  1.00 106.18 ? 500 TRP B CZ2 1 
ATOM   9636  C CZ3 . TRP B 1 480 ? 137.117 104.307 98.026  1.00 105.20 ? 500 TRP B CZ3 1 
ATOM   9637  C CH2 . TRP B 1 480 ? 137.771 105.401 97.461  1.00 105.56 ? 500 TRP B CH2 1 
ATOM   9638  N N   . SER B 1 481 ? 141.059 97.178  98.176  1.00 136.06 ? 501 SER B N   1 
ATOM   9639  C CA  . SER B 1 481 ? 140.919 95.830  98.707  1.00 144.26 ? 501 SER B CA  1 
ATOM   9640  C C   . SER B 1 481 ? 141.567 95.741  100.087 1.00 152.80 ? 501 SER B C   1 
ATOM   9641  O O   . SER B 1 481 ? 142.447 94.911  100.312 1.00 154.60 ? 501 SER B O   1 
ATOM   9642  C CB  . SER B 1 481 ? 141.496 94.815  97.752  1.00 144.82 ? 501 SER B CB  1 
ATOM   9643  O OG  . SER B 1 481 ? 141.329 93.497  98.256  1.00 145.71 ? 501 SER B OG  1 
ATOM   9644  N N   . LYS B 1 482 ? 141.094 96.595  101.006 1.00 160.38 ? 502 LYS B N   1 
ATOM   9645  C CA  . LYS B 1 482 ? 141.653 96.751  102.340 1.00 166.37 ? 502 LYS B CA  1 
ATOM   9646  C C   . LYS B 1 482 ? 140.893 97.865  103.056 1.00 169.49 ? 502 LYS B C   1 
ATOM   9647  O O   . LYS B 1 482 ? 140.147 98.611  102.427 1.00 167.91 ? 502 LYS B O   1 
ATOM   9648  C CB  . LYS B 1 482 ? 143.153 97.071  102.294 1.00 168.44 ? 502 LYS B CB  1 
ATOM   9649  C CG  . LYS B 1 482 ? 143.558 98.242  101.408 1.00 169.88 ? 502 LYS B CG  1 
ATOM   9650  C CD  . LYS B 1 482 ? 145.058 98.451  101.367 1.00 172.05 ? 502 LYS B CD  1 
ATOM   9651  C CE  . LYS B 1 482 ? 145.480 99.508  100.369 1.00 173.08 ? 502 LYS B CE  1 
ATOM   9652  N NZ  . LYS B 1 482 ? 146.950 99.696  100.364 1.00 174.06 ? 502 LYS B NZ  1 
ATOM   9653  N N   . LYS B 1 483 ? 141.105 97.975  104.372 1.00 174.27 ? 503 LYS B N   1 
ATOM   9654  C CA  . LYS B 1 483 ? 140.463 98.999  105.181 1.00 177.35 ? 503 LYS B CA  1 
ATOM   9655  C C   . LYS B 1 483 ? 141.196 100.333 105.039 1.00 171.17 ? 503 LYS B C   1 
ATOM   9656  O O   . LYS B 1 483 ? 140.667 101.366 105.445 1.00 168.41 ? 503 LYS B O   1 
ATOM   9657  C CB  . LYS B 1 483 ? 140.420 98.562  106.649 1.00 185.32 ? 503 LYS B CB  1 
ATOM   9658  C CG  . LYS B 1 483 ? 139.538 97.354  106.944 1.00 190.46 ? 503 LYS B CG  1 
ATOM   9659  C CD  . LYS B 1 483 ? 139.499 96.981  108.411 1.00 193.41 ? 503 LYS B CD  1 
ATOM   9660  C CE  . LYS B 1 483 ? 138.542 95.846  108.709 1.00 194.38 ? 503 LYS B CE  1 
ATOM   9661  N NZ  . LYS B 1 483 ? 138.490 95.541  110.158 1.00 195.11 ? 503 LYS B NZ  1 
ATOM   9662  N N   . SER B 1 484 ? 142.414 100.304 104.479 1.00 165.06 ? 504 SER B N   1 
ATOM   9663  C CA  . SER B 1 484 ? 143.220 101.500 104.297 1.00 160.12 ? 504 SER B CA  1 
ATOM   9664  C C   . SER B 1 484 ? 142.979 102.092 102.910 1.00 152.21 ? 504 SER B C   1 
ATOM   9665  O O   . SER B 1 484 ? 143.807 101.938 102.014 1.00 149.74 ? 504 SER B O   1 
ATOM   9666  C CB  . SER B 1 484 ? 144.678 101.188 104.520 1.00 161.52 ? 504 SER B CB  1 
ATOM   9667  O OG  . SER B 1 484 ? 144.909 100.774 105.860 1.00 162.94 ? 504 SER B OG  1 
ATOM   9668  N N   . ASN B 1 485 ? 141.838 102.773 102.749 1.00 144.83 ? 505 ASN B N   1 
ATOM   9669  C CA  . ASN B 1 485 ? 141.505 103.427 101.495 1.00 136.95 ? 505 ASN B CA  1 
ATOM   9670  C C   . ASN B 1 485 ? 142.230 104.770 101.434 1.00 135.51 ? 505 ASN B C   1 
ATOM   9671  O O   . ASN B 1 485 ? 143.069 105.066 102.285 1.00 135.58 ? 505 ASN B O   1 
ATOM   9672  C CB  . ASN B 1 485 ? 139.993 103.589 101.326 1.00 131.93 ? 505 ASN B CB  1 
ATOM   9673  C CG  . ASN B 1 485 ? 139.391 104.571 102.306 1.00 127.65 ? 505 ASN B CG  1 
ATOM   9674  O OD1 . ASN B 1 485 ? 139.947 104.806 103.377 1.00 126.88 ? 505 ASN B OD1 1 
ATOM   9675  N ND2 . ASN B 1 485 ? 138.246 105.132 101.954 1.00 126.77 ? 505 ASN B ND2 1 
ATOM   9676  N N   . ILE B 1 486 ? 141.902 105.577 100.419 1.00 132.49 ? 506 ILE B N   1 
ATOM   9677  C CA  . ILE B 1 486 ? 142.488 106.902 100.308 1.00 128.63 ? 506 ILE B CA  1 
ATOM   9678  C C   . ILE B 1 486 ? 142.019 107.737 101.495 1.00 130.82 ? 506 ILE B C   1 
ATOM   9679  O O   . ILE B 1 486 ? 140.900 107.573 101.972 1.00 126.88 ? 506 ILE B O   1 
ATOM   9680  C CB  . ILE B 1 486 ? 142.138 107.577 98.967  1.00 122.58 ? 506 ILE B CB  1 
ATOM   9681  C CG1 . ILE B 1 486 ? 143.094 108.730 98.646  1.00 122.24 ? 506 ILE B CG1 1 
ATOM   9682  C CG2 . ILE B 1 486 ? 140.688 108.028 98.954  1.00 120.49 ? 506 ILE B CG2 1 
ATOM   9683  C CD1 . ILE B 1 486 ? 144.520 108.296 98.387  1.00 124.50 ? 506 ILE B CD1 1 
ATOM   9684  N N   . ILE B 1 487 ? 142.891 108.638 101.952 1.00 137.46 ? 507 ILE B N   1 
ATOM   9685  C CA  . ILE B 1 487 ? 142.558 109.532 103.048 1.00 141.63 ? 507 ILE B CA  1 
ATOM   9686  C C   . ILE B 1 487 ? 141.359 110.371 102.615 1.00 136.78 ? 507 ILE B C   1 
ATOM   9687  O O   . ILE B 1 487 ? 141.419 111.055 101.598 1.00 134.51 ? 507 ILE B O   1 
ATOM   9688  C CB  . ILE B 1 487 ? 143.758 110.418 103.449 1.00 146.55 ? 507 ILE B CB  1 
ATOM   9689  C CG1 . ILE B 1 487 ? 144.994 109.600 103.835 1.00 150.20 ? 507 ILE B CG1 1 
ATOM   9690  C CG2 . ILE B 1 487 ? 143.364 111.376 104.562 1.00 146.31 ? 507 ILE B CG2 1 
ATOM   9691  C CD1 . ILE B 1 487 ? 146.256 110.425 103.964 1.00 151.16 ? 507 ILE B CD1 1 
ATOM   9692  N N   . ARG B 1 488 ? 140.274 110.299 103.389 1.00 136.56 ? 508 ARG B N   1 
ATOM   9693  C CA  . ARG B 1 488 ? 139.060 111.044 103.093 1.00 138.70 ? 508 ARG B CA  1 
ATOM   9694  C C   . ARG B 1 488 ? 139.414 112.519 102.924 1.00 128.49 ? 508 ARG B C   1 
ATOM   9695  O O   . ARG B 1 488 ? 140.030 113.109 103.806 1.00 129.17 ? 508 ARG B O   1 
ATOM   9696  C CB  . ARG B 1 488 ? 138.034 110.867 104.217 1.00 149.74 ? 508 ARG B CB  1 
ATOM   9697  C CG  . ARG B 1 488 ? 137.595 109.429 104.457 1.00 157.49 ? 508 ARG B CG  1 
ATOM   9698  C CD  . ARG B 1 488 ? 136.864 109.286 105.778 1.00 163.86 ? 508 ARG B CD  1 
ATOM   9699  N NE  . ARG B 1 488 ? 137.727 109.606 106.910 1.00 168.54 ? 508 ARG B NE  1 
ATOM   9700  C CZ  . ARG B 1 488 ? 137.320 109.722 108.172 1.00 174.63 ? 508 ARG B CZ  1 
ATOM   9701  N NH1 . ARG B 1 488 ? 136.046 109.558 108.485 1.00 175.94 ? 508 ARG B NH1 1 
ATOM   9702  N NH2 . ARG B 1 488 ? 138.194 110.009 109.123 1.00 176.60 ? 508 ARG B NH2 1 
ATOM   9703  N N   . SER B 1 489 ? 139.046 113.096 101.776 1.00 116.83 ? 509 SER B N   1 
ATOM   9704  C CA  . SER B 1 489 ? 139.314 114.497 101.495 1.00 109.59 ? 509 SER B CA  1 
ATOM   9705  C C   . SER B 1 489 ? 138.426 115.385 102.363 1.00 105.80 ? 509 SER B C   1 
ATOM   9706  O O   . SER B 1 489 ? 137.420 115.917 101.897 1.00 103.40 ? 509 SER B O   1 
ATOM   9707  C CB  . SER B 1 489 ? 139.136 114.796 100.032 1.00 107.00 ? 509 SER B CB  1 
ATOM   9708  O OG  . SER B 1 489 ? 137.773 114.725 99.647  1.00 104.49 ? 509 SER B OG  1 
ATOM   9709  N N   . VAL B 1 490 ? 138.830 115.535 103.628 1.00 102.58 ? 510 VAL B N   1 
ATOM   9710  C CA  . VAL B 1 490 ? 138.184 116.447 104.556 1.00 100.90 ? 510 VAL B CA  1 
ATOM   9711  C C   . VAL B 1 490 ? 139.245 117.410 105.078 1.00 100.95 ? 510 VAL B C   1 
ATOM   9712  O O   . VAL B 1 490 ? 140.373 117.000 105.348 1.00 102.97 ? 510 VAL B O   1 
ATOM   9713  C CB  . VAL B 1 490 ? 137.489 115.694 105.707 1.00 103.05 ? 510 VAL B CB  1 
ATOM   9714  C CG1 . VAL B 1 490 ? 136.219 115.006 105.235 1.00 104.09 ? 510 VAL B CG1 1 
ATOM   9715  C CG2 . VAL B 1 490 ? 138.414 114.697 106.392 1.00 103.82 ? 510 VAL B CG2 1 
ATOM   9716  N N   . CYS B 1 491 ? 138.868 118.684 105.236 1.00 101.58 ? 511 CYS B N   1 
ATOM   9717  C CA  . CYS B 1 491 ? 139.778 119.699 105.745 1.00 103.37 ? 511 CYS B CA  1 
ATOM   9718  C C   . CYS B 1 491 ? 139.529 119.952 107.232 1.00 107.59 ? 511 CYS B C   1 
ATOM   9719  O O   . CYS B 1 491 ? 140.048 120.913 107.795 1.00 107.38 ? 511 CYS B O   1 
ATOM   9720  C CB  . CYS B 1 491 ? 139.643 121.004 104.966 1.00 102.37 ? 511 CYS B CB  1 
ATOM   9721  S SG  . CYS B 1 491 ? 138.005 121.768 105.076 1.00 103.26 ? 511 CYS B SG  1 
ATOM   9722  N N   . SER B 1 492 ? 138.715 119.100 107.864 1.00 114.44 ? 512 SER B N   1 
ATOM   9723  C CA  . SER B 1 492 ? 138.343 119.293 109.255 1.00 120.48 ? 512 SER B CA  1 
ATOM   9724  C C   . SER B 1 492 ? 138.036 117.941 109.892 1.00 128.50 ? 512 SER B C   1 
ATOM   9725  O O   . SER B 1 492 ? 137.070 117.278 109.515 1.00 128.77 ? 512 SER B O   1 
ATOM   9726  C CB  . SER B 1 492 ? 137.178 120.250 109.367 1.00 120.47 ? 512 SER B CB  1 
ATOM   9727  O OG  . SER B 1 492 ? 136.005 119.690 108.790 1.00 120.07 ? 512 SER B OG  1 
ATOM   9728  N N   . GLU B 1 493 ? 138.900 117.527 110.823 1.00 138.35 ? 513 GLU B N   1 
ATOM   9729  C CA  . GLU B 1 493 ? 138.711 116.288 111.560 1.00 146.74 ? 513 GLU B CA  1 
ATOM   9730  C C   . GLU B 1 493 ? 137.382 116.363 112.306 1.00 151.27 ? 513 GLU B C   1 
ATOM   9731  O O   . GLU B 1 493 ? 137.087 117.363 112.954 1.00 148.91 ? 513 GLU B O   1 
ATOM   9732  C CB  . GLU B 1 493 ? 139.896 116.015 112.494 1.00 150.24 ? 513 GLU B CB  1 
ATOM   9733  C CG  . GLU B 1 493 ? 140.209 117.119 113.503 1.00 153.37 ? 513 GLU B CG  1 
ATOM   9734  C CD  . GLU B 1 493 ? 140.876 118.368 112.946 1.00 155.96 ? 513 GLU B CD  1 
ATOM   9735  O OE1 . GLU B 1 493 ? 141.322 119.207 113.752 1.00 158.01 ? 513 GLU B OE1 1 
ATOM   9736  O OE2 . GLU B 1 493 ? 140.922 118.511 111.704 1.00 156.34 ? 513 GLU B OE2 1 
ATOM   9737  N N   . PRO B 1 494 ? 136.498 115.347 112.176 1.00 159.75 ? 514 PRO B N   1 
ATOM   9738  C CA  . PRO B 1 494 ? 135.154 115.427 112.745 1.00 163.35 ? 514 PRO B CA  1 
ATOM   9739  C C   . PRO B 1 494 ? 135.230 115.381 114.267 1.00 167.71 ? 514 PRO B C   1 
ATOM   9740  O O   . PRO B 1 494 ? 135.508 114.333 114.846 1.00 169.34 ? 514 PRO B O   1 
ATOM   9741  C CB  . PRO B 1 494 ? 134.426 114.210 112.153 1.00 164.72 ? 514 PRO B CB  1 
ATOM   9742  C CG  . PRO B 1 494 ? 135.536 113.226 111.824 1.00 165.51 ? 514 PRO B CG  1 
ATOM   9743  C CD  . PRO B 1 494 ? 136.739 114.079 111.473 1.00 163.15 ? 514 PRO B CD  1 
ATOM   9744  N N   . CYS B 1 495 ? 135.000 116.538 114.899 1.00 172.41 ? 515 CYS B N   1 
ATOM   9745  C CA  . CYS B 1 495 ? 135.187 116.683 116.335 1.00 175.97 ? 515 CYS B CA  1 
ATOM   9746  C C   . CYS B 1 495 ? 133.831 116.628 117.042 1.00 186.70 ? 515 CYS B C   1 
ATOM   9747  O O   . CYS B 1 495 ? 133.562 117.378 117.986 1.00 185.55 ? 515 CYS B O   1 
ATOM   9748  C CB  . CYS B 1 495 ? 135.955 117.957 116.666 1.00 169.41 ? 515 CYS B CB  1 
ATOM   9749  S SG  . CYS B 1 495 ? 135.083 119.490 116.256 1.00 159.10 ? 515 CYS B SG  1 
ATOM   9750  N N   . GLU B 1 496 ? 132.988 115.694 116.594 1.00 199.25 ? 516 GLU B N   1 
ATOM   9751  C CA  . GLU B 1 496 ? 131.703 115.430 117.219 1.00 209.55 ? 516 GLU B CA  1 
ATOM   9752  C C   . GLU B 1 496 ? 131.930 114.526 118.431 1.00 211.70 ? 516 GLU B C   1 
ATOM   9753  O O   . GLU B 1 496 ? 131.461 113.387 118.466 1.00 213.45 ? 516 GLU B O   1 
ATOM   9754  C CB  . GLU B 1 496 ? 130.761 114.792 116.195 1.00 215.48 ? 516 GLU B CB  1 
ATOM   9755  C CG  . GLU B 1 496 ? 129.294 114.943 116.550 1.00 218.88 ? 516 GLU B CG  1 
ATOM   9756  C CD  . GLU B 1 496 ? 128.789 116.375 116.494 1.00 219.47 ? 516 GLU B CD  1 
ATOM   9757  O OE1 . GLU B 1 496 ? 129.486 117.226 115.904 1.00 217.46 ? 516 GLU B OE1 1 
ATOM   9758  O OE2 . GLU B 1 496 ? 127.705 116.641 117.051 1.00 218.89 ? 516 GLU B OE2 1 
ATOM   9759  N N   . LYS B 1 497 ? 132.662 115.056 119.420 1.00 211.10 ? 517 LYS B N   1 
ATOM   9760  C CA  . LYS B 1 497 ? 133.095 114.282 120.573 1.00 210.59 ? 517 LYS B CA  1 
ATOM   9761  C C   . LYS B 1 497 ? 132.496 114.898 121.835 1.00 203.07 ? 517 LYS B C   1 
ATOM   9762  O O   . LYS B 1 497 ? 133.179 115.089 122.840 1.00 200.91 ? 517 LYS B O   1 
ATOM   9763  C CB  . LYS B 1 497 ? 134.625 114.233 120.608 1.00 216.20 ? 517 LYS B CB  1 
ATOM   9764  C CG  . LYS B 1 497 ? 135.225 113.147 121.493 1.00 221.79 ? 517 LYS B CG  1 
ATOM   9765  C CD  . LYS B 1 497 ? 136.716 112.943 121.291 1.00 225.12 ? 517 LYS B CD  1 
ATOM   9766  C CE  . LYS B 1 497 ? 137.543 114.192 121.516 1.00 227.77 ? 517 LYS B CE  1 
ATOM   9767  N NZ  . LYS B 1 497 ? 137.359 114.744 122.880 1.00 229.22 ? 517 LYS B NZ  1 
ATOM   9768  N N   . GLY B 1 498 ? 131.197 115.214 121.754 1.00 195.90 ? 518 GLY B N   1 
ATOM   9769  C CA  . GLY B 1 498 ? 130.436 115.727 122.880 1.00 189.38 ? 518 GLY B CA  1 
ATOM   9770  C C   . GLY B 1 498 ? 130.475 117.252 122.972 1.00 182.73 ? 518 GLY B C   1 
ATOM   9771  O O   . GLY B 1 498 ? 129.681 117.937 122.334 1.00 180.54 ? 518 GLY B O   1 
ATOM   9772  N N   . GLN B 1 499 ? 131.434 117.758 123.756 1.00 176.11 ? 519 GLN B N   1 
ATOM   9773  C CA  . GLN B 1 499 ? 131.401 119.111 124.291 1.00 171.66 ? 519 GLN B CA  1 
ATOM   9774  C C   . GLN B 1 499 ? 131.912 120.121 123.264 1.00 159.97 ? 519 GLN B C   1 
ATOM   9775  O O   . GLN B 1 499 ? 131.450 121.262 123.229 1.00 159.44 ? 519 GLN B O   1 
ATOM   9776  C CB  . GLN B 1 499 ? 132.239 119.150 125.572 1.00 177.85 ? 519 GLN B CB  1 
ATOM   9777  C CG  . GLN B 1 499 ? 132.440 120.536 126.167 1.00 181.76 ? 519 GLN B CG  1 
ATOM   9778  C CD  . GLN B 1 499 ? 131.204 121.091 126.835 1.00 181.83 ? 519 GLN B CD  1 
ATOM   9779  O OE1 . GLN B 1 499 ? 130.376 121.750 126.211 1.00 179.98 ? 519 GLN B OE1 1 
ATOM   9780  N NE2 . GLN B 1 499 ? 131.095 120.876 128.137 1.00 180.48 ? 519 GLN B NE2 1 
ATOM   9781  N N   . ILE B 1 500 ? 132.859 119.689 122.431 1.00 148.91 ? 520 ILE B N   1 
ATOM   9782  C CA  . ILE B 1 500 ? 133.548 120.596 121.527 1.00 140.57 ? 520 ILE B CA  1 
ATOM   9783  C C   . ILE B 1 500 ? 132.614 120.956 120.376 1.00 134.16 ? 520 ILE B C   1 
ATOM   9784  O O   . ILE B 1 500 ? 131.944 120.089 119.824 1.00 135.85 ? 520 ILE B O   1 
ATOM   9785  C CB  . ILE B 1 500 ? 134.881 119.998 121.034 1.00 139.50 ? 520 ILE B CB  1 
ATOM   9786  C CG1 . ILE B 1 500 ? 134.754 118.495 120.760 1.00 140.32 ? 520 ILE B CG1 1 
ATOM   9787  C CG2 . ILE B 1 500 ? 135.995 120.314 122.022 1.00 138.33 ? 520 ILE B CG2 1 
ATOM   9788  C CD1 . ILE B 1 500 ? 135.995 117.856 120.178 1.00 139.51 ? 520 ILE B CD1 1 
ATOM   9789  N N   . LYS B 1 501 ? 132.598 122.248 120.028 1.00 125.74 ? 521 LYS B N   1 
ATOM   9790  C CA  . LYS B 1 501 ? 131.734 122.793 118.995 1.00 119.58 ? 521 LYS B CA  1 
ATOM   9791  C C   . LYS B 1 501 ? 132.573 123.284 117.816 1.00 119.02 ? 521 LYS B C   1 
ATOM   9792  O O   . LYS B 1 501 ? 133.796 123.269 117.876 1.00 119.98 ? 521 LYS B O   1 
ATOM   9793  C CB  . LYS B 1 501 ? 130.929 123.950 119.585 1.00 116.23 ? 521 LYS B CB  1 
ATOM   9794  C CG  . LYS B 1 501 ? 131.671 125.277 119.658 1.00 116.32 ? 521 LYS B CG  1 
ATOM   9795  C CD  . LYS B 1 501 ? 130.927 126.349 120.415 1.00 118.47 ? 521 LYS B CD  1 
ATOM   9796  C CE  . LYS B 1 501 ? 129.585 126.690 119.803 1.00 119.75 ? 521 LYS B CE  1 
ATOM   9797  N NZ  . LYS B 1 501 ? 129.113 128.018 120.256 1.00 120.81 ? 521 LYS B NZ  1 
ATOM   9798  N N   . VAL B 1 502 ? 131.889 123.746 116.764 1.00 117.24 ? 522 VAL B N   1 
ATOM   9799  C CA  . VAL B 1 502 ? 132.497 124.118 115.494 1.00 115.19 ? 522 VAL B CA  1 
ATOM   9800  C C   . VAL B 1 502 ? 132.421 125.635 115.317 1.00 112.93 ? 522 VAL B C   1 
ATOM   9801  O O   . VAL B 1 502 ? 131.353 126.209 115.496 1.00 112.25 ? 522 VAL B O   1 
ATOM   9802  C CB  . VAL B 1 502 ? 131.762 123.385 114.352 1.00 116.32 ? 522 VAL B CB  1 
ATOM   9803  C CG1 . VAL B 1 502 ? 131.997 124.014 112.986 1.00 117.09 ? 522 VAL B CG1 1 
ATOM   9804  C CG2 . VAL B 1 502 ? 132.108 121.904 114.334 1.00 116.60 ? 522 VAL B CG2 1 
ATOM   9805  N N   . ILE B 1 503 ? 133.533 126.275 114.933 1.00 112.43 ? 523 ILE B N   1 
ATOM   9806  C CA  . ILE B 1 503 ? 133.511 127.690 114.584 1.00 113.75 ? 523 ILE B CA  1 
ATOM   9807  C C   . ILE B 1 503 ? 134.240 127.891 113.258 1.00 116.98 ? 523 ILE B C   1 
ATOM   9808  O O   . ILE B 1 503 ? 135.339 127.376 113.068 1.00 116.67 ? 523 ILE B O   1 
ATOM   9809  C CB  . ILE B 1 503 ? 134.105 128.565 115.708 1.00 115.81 ? 523 ILE B CB  1 
ATOM   9810  C CG1 . ILE B 1 503 ? 133.232 128.517 116.968 1.00 120.73 ? 523 ILE B CG1 1 
ATOM   9811  C CG2 . ILE B 1 503 ? 134.317 129.991 115.214 1.00 115.14 ? 523 ILE B CG2 1 
ATOM   9812  C CD1 . ILE B 1 503 ? 133.844 129.167 118.190 1.00 123.40 ? 523 ILE B CD1 1 
ATOM   9813  N N   . ARG B 1 504 ? 133.617 128.667 112.357 1.00 120.78 ? 524 ARG B N   1 
ATOM   9814  C CA  . ARG B 1 504 ? 134.165 128.979 111.044 1.00 124.39 ? 524 ARG B CA  1 
ATOM   9815  C C   . ARG B 1 504 ? 134.772 130.383 111.062 1.00 128.07 ? 524 ARG B C   1 
ATOM   9816  O O   . ARG B 1 504 ? 134.527 131.160 111.985 1.00 131.29 ? 524 ARG B O   1 
ATOM   9817  C CB  . ARG B 1 504 ? 133.072 128.809 109.981 1.00 126.03 ? 524 ARG B CB  1 
ATOM   9818  C CG  . ARG B 1 504 ? 132.846 127.355 109.594 1.00 130.81 ? 524 ARG B CG  1 
ATOM   9819  C CD  . ARG B 1 504 ? 131.430 127.032 109.147 1.00 136.35 ? 524 ARG B CD  1 
ATOM   9820  N NE  . ARG B 1 504 ? 131.313 125.605 108.888 1.00 142.02 ? 524 ARG B NE  1 
ATOM   9821  C CZ  . ARG B 1 504 ? 130.238 124.990 108.415 1.00 147.88 ? 524 ARG B CZ  1 
ATOM   9822  N NH1 . ARG B 1 504 ? 129.149 125.671 108.104 1.00 149.68 ? 524 ARG B NH1 1 
ATOM   9823  N NH2 . ARG B 1 504 ? 130.259 123.676 108.261 1.00 147.50 ? 524 ARG B NH2 1 
ATOM   9824  N N   . LYS B 1 505 ? 135.525 130.723 110.004 1.00 130.75 ? 525 LYS B N   1 
ATOM   9825  C CA  . LYS B 1 505 ? 136.552 131.754 110.098 1.00 133.63 ? 525 LYS B CA  1 
ATOM   9826  C C   . LYS B 1 505 ? 136.914 132.345 108.731 1.00 134.38 ? 525 LYS B C   1 
ATOM   9827  O O   . LYS B 1 505 ? 138.096 132.474 108.400 1.00 133.99 ? 525 LYS B O   1 
ATOM   9828  C CB  . LYS B 1 505 ? 137.791 131.146 110.763 1.00 136.01 ? 525 LYS B CB  1 
ATOM   9829  C CG  . LYS B 1 505 ? 138.298 129.867 110.108 1.00 138.39 ? 525 LYS B CG  1 
ATOM   9830  C CD  . LYS B 1 505 ? 139.445 129.201 110.832 1.00 140.59 ? 525 LYS B CD  1 
ATOM   9831  C CE  . LYS B 1 505 ? 139.871 127.907 110.169 1.00 140.25 ? 525 LYS B CE  1 
ATOM   9832  N NZ  . LYS B 1 505 ? 138.752 126.938 110.088 1.00 139.50 ? 525 LYS B NZ  1 
ATOM   9833  N N   . GLY B 1 506 ? 135.896 132.742 107.958 1.00 134.41 ? 526 GLY B N   1 
ATOM   9834  C CA  . GLY B 1 506 ? 136.088 133.592 106.791 1.00 134.23 ? 526 GLY B CA  1 
ATOM   9835  C C   . GLY B 1 506 ? 136.251 132.821 105.483 1.00 134.45 ? 526 GLY B C   1 
ATOM   9836  O O   . GLY B 1 506 ? 136.174 133.418 104.412 1.00 133.81 ? 526 GLY B O   1 
ATOM   9837  N N   . GLU B 1 507 ? 136.460 131.501 105.590 1.00 134.68 ? 527 GLU B N   1 
ATOM   9838  C CA  . GLU B 1 507 ? 136.836 130.656 104.464 1.00 132.68 ? 527 GLU B CA  1 
ATOM   9839  C C   . GLU B 1 507 ? 135.673 129.728 104.119 1.00 126.96 ? 527 GLU B C   1 
ATOM   9840  O O   . GLU B 1 507 ? 134.563 129.932 104.606 1.00 125.71 ? 527 GLU B O   1 
ATOM   9841  C CB  . GLU B 1 507 ? 138.103 129.871 104.822 1.00 136.13 ? 527 GLU B CB  1 
ATOM   9842  C CG  . GLU B 1 507 ? 139.175 130.718 105.493 1.00 140.78 ? 527 GLU B CG  1 
ATOM   9843  C CD  . GLU B 1 507 ? 139.526 132.002 104.757 1.00 145.36 ? 527 GLU B CD  1 
ATOM   9844  O OE1 . GLU B 1 507 ? 139.940 131.914 103.585 1.00 148.57 ? 527 GLU B OE1 1 
ATOM   9845  O OE2 . GLU B 1 507 ? 139.365 133.090 105.354 1.00 146.35 ? 527 GLU B OE2 1 
ATOM   9846  N N   . VAL B 1 508 ? 135.936 128.732 103.258 1.00 119.81 ? 528 VAL B N   1 
ATOM   9847  C CA  . VAL B 1 508 ? 134.953 127.719 102.902 1.00 114.25 ? 528 VAL B CA  1 
ATOM   9848  C C   . VAL B 1 508 ? 134.289 127.214 104.183 1.00 111.95 ? 528 VAL B C   1 
ATOM   9849  O O   . VAL B 1 508 ? 134.964 126.722 105.084 1.00 111.39 ? 528 VAL B O   1 
ATOM   9850  C CB  . VAL B 1 508 ? 135.578 126.574 102.074 1.00 111.01 ? 528 VAL B CB  1 
ATOM   9851  C CG1 . VAL B 1 508 ? 136.738 125.887 102.786 1.00 109.75 ? 528 VAL B CG1 1 
ATOM   9852  C CG2 . VAL B 1 508 ? 134.534 125.551 101.648 1.00 110.63 ? 528 VAL B CG2 1 
ATOM   9853  N N   . SER B 1 509 ? 132.960 127.360 104.259 1.00 109.34 ? 529 SER B N   1 
ATOM   9854  C CA  . SER B 1 509 ? 132.198 126.991 105.444 1.00 107.02 ? 529 SER B CA  1 
ATOM   9855  C C   . SER B 1 509 ? 132.261 125.481 105.649 1.00 101.88 ? 529 SER B C   1 
ATOM   9856  O O   . SER B 1 509 ? 131.243 124.831 105.887 1.00 100.35 ? 529 SER B O   1 
ATOM   9857  C CB  . SER B 1 509 ? 130.772 127.469 105.339 1.00 108.94 ? 529 SER B CB  1 
ATOM   9858  O OG  . SER B 1 509 ? 130.121 126.864 104.231 1.00 110.40 ? 529 SER B OG  1 
ATOM   9859  N N   . CYS B 1 510 ? 133.482 124.949 105.626 1.00 98.76  ? 530 CYS B N   1 
ATOM   9860  C CA  . CYS B 1 510 ? 133.707 123.519 105.503 1.00 97.52  ? 530 CYS B CA  1 
ATOM   9861  C C   . CYS B 1 510 ? 134.886 123.084 106.367 1.00 97.09  ? 530 CYS B C   1 
ATOM   9862  O O   . CYS B 1 510 ? 134.965 121.928 106.778 1.00 96.16  ? 530 CYS B O   1 
ATOM   9863  C CB  . CYS B 1 510 ? 134.008 123.169 104.057 1.00 98.00  ? 530 CYS B CB  1 
ATOM   9864  S SG  . CYS B 1 510 ? 133.348 121.566 103.549 1.00 95.30  ? 530 CYS B SG  1 
ATOM   9865  N N   . CYS B 1 511 ? 135.834 124.007 106.561 1.00 98.76  ? 531 CYS B N   1 
ATOM   9866  C CA  . CYS B 1 511 ? 136.977 123.810 107.432 1.00 102.24 ? 531 CYS B CA  1 
ATOM   9867  C C   . CYS B 1 511 ? 136.748 124.616 108.705 1.00 105.92 ? 531 CYS B C   1 
ATOM   9868  O O   . CYS B 1 511 ? 136.492 125.817 108.641 1.00 108.02 ? 531 CYS B O   1 
ATOM   9869  C CB  . CYS B 1 511 ? 138.265 124.273 106.761 1.00 102.98 ? 531 CYS B CB  1 
ATOM   9870  S SG  . CYS B 1 511 ? 138.449 123.743 105.036 1.00 105.74 ? 531 CYS B SG  1 
ATOM   9871  N N   . TRP B 1 512 ? 136.810 123.936 109.849 1.00 107.11 ? 532 TRP B N   1 
ATOM   9872  C CA  . TRP B 1 512 ? 136.448 124.554 111.112 1.00 107.74 ? 532 TRP B CA  1 
ATOM   9873  C C   . TRP B 1 512 ? 137.529 124.295 112.151 1.00 110.95 ? 532 TRP B C   1 
ATOM   9874  O O   . TRP B 1 512 ? 138.343 123.383 112.006 1.00 110.14 ? 532 TRP B O   1 
ATOM   9875  C CB  . TRP B 1 512 ? 135.087 124.045 111.594 1.00 105.96 ? 532 TRP B CB  1 
ATOM   9876  C CG  . TRP B 1 512 ? 134.950 122.555 111.594 1.00 107.65 ? 532 TRP B CG  1 
ATOM   9877  C CD1 . TRP B 1 512 ? 135.703 121.646 112.280 1.00 108.65 ? 532 TRP B CD1 1 
ATOM   9878  C CD2 . TRP B 1 512 ? 133.989 121.786 110.848 1.00 110.41 ? 532 TRP B CD2 1 
ATOM   9879  N NE1 . TRP B 1 512 ? 135.276 120.373 112.020 1.00 109.60 ? 532 TRP B NE1 1 
ATOM   9880  C CE2 . TRP B 1 512 ? 134.225 120.426 111.145 1.00 110.38 ? 532 TRP B CE2 1 
ATOM   9881  C CE3 . TRP B 1 512 ? 132.953 122.108 109.963 1.00 113.55 ? 532 TRP B CE3 1 
ATOM   9882  C CZ2 . TRP B 1 512 ? 133.464 119.398 110.591 1.00 112.55 ? 532 TRP B CZ2 1 
ATOM   9883  C CZ3 . TRP B 1 512 ? 132.199 121.092 109.417 1.00 114.98 ? 532 TRP B CZ3 1 
ATOM   9884  C CH2 . TRP B 1 512 ? 132.455 119.756 109.726 1.00 114.79 ? 532 TRP B CH2 1 
ATOM   9885  N N   . THR B 1 513 ? 137.528 125.145 113.182 1.00 114.64 ? 533 THR B N   1 
ATOM   9886  C CA  . THR B 1 513 ? 138.311 124.930 114.386 1.00 116.72 ? 533 THR B CA  1 
ATOM   9887  C C   . THR B 1 513 ? 137.344 124.543 115.499 1.00 121.34 ? 533 THR B C   1 
ATOM   9888  O O   . THR B 1 513 ? 136.242 125.079 115.562 1.00 121.76 ? 533 THR B O   1 
ATOM   9889  C CB  . THR B 1 513 ? 139.129 126.178 114.733 1.00 114.96 ? 533 THR B CB  1 
ATOM   9890  O OG1 . THR B 1 513 ? 138.229 127.278 114.880 1.00 114.35 ? 533 THR B OG1 1 
ATOM   9891  C CG2 . THR B 1 513 ? 140.172 126.502 113.686 1.00 114.89 ? 533 THR B CG2 1 
ATOM   9892  N N   . CYS B 1 514 ? 137.758 123.600 116.347 1.00 126.30 ? 534 CYS B N   1 
ATOM   9893  C CA  . CYS B 1 514 ? 136.873 123.074 117.370 1.00 130.70 ? 534 CYS B CA  1 
ATOM   9894  C C   . CYS B 1 514 ? 137.203 123.719 118.710 1.00 130.96 ? 534 CYS B C   1 
ATOM   9895  O O   . CYS B 1 514 ? 138.362 123.750 119.122 1.00 132.47 ? 534 CYS B O   1 
ATOM   9896  C CB  . CYS B 1 514 ? 136.973 121.557 117.451 1.00 135.84 ? 534 CYS B CB  1 
ATOM   9897  S SG  . CYS B 1 514 ? 136.629 120.747 115.868 1.00 144.54 ? 534 CYS B SG  1 
ATOM   9898  N N   . THR B 1 515 ? 136.167 124.256 119.364 1.00 129.29 ? 535 THR B N   1 
ATOM   9899  C CA  . THR B 1 515 ? 136.323 124.947 120.632 1.00 128.04 ? 535 THR B CA  1 
ATOM   9900  C C   . THR B 1 515 ? 135.417 124.307 121.677 1.00 129.16 ? 535 THR B C   1 
ATOM   9901  O O   . THR B 1 515 ? 134.239 124.070 121.418 1.00 129.49 ? 535 THR B O   1 
ATOM   9902  C CB  . THR B 1 515 ? 136.012 126.438 120.482 1.00 125.28 ? 535 THR B CB  1 
ATOM   9903  O OG1 . THR B 1 515 ? 134.641 126.556 120.100 1.00 123.06 ? 535 THR B OG1 1 
ATOM   9904  C CG2 . THR B 1 515 ? 136.912 127.112 119.470 1.00 124.82 ? 535 THR B CG2 1 
ATOM   9905  N N   . PRO B 1 516 ? 135.930 124.003 122.889 1.00 129.81 ? 536 PRO B N   1 
ATOM   9906  C CA  . PRO B 1 516 ? 135.108 123.385 123.927 1.00 129.29 ? 536 PRO B CA  1 
ATOM   9907  C C   . PRO B 1 516 ? 134.162 124.422 124.522 1.00 128.44 ? 536 PRO B C   1 
ATOM   9908  O O   . PRO B 1 516 ? 134.573 125.539 124.831 1.00 128.10 ? 536 PRO B O   1 
ATOM   9909  C CB  . PRO B 1 516 ? 136.133 122.885 124.956 1.00 130.32 ? 536 PRO B CB  1 
ATOM   9910  C CG  . PRO B 1 516 ? 137.318 123.820 124.790 1.00 130.69 ? 536 PRO B CG  1 
ATOM   9911  C CD  . PRO B 1 516 ? 137.309 124.250 123.337 1.00 130.23 ? 536 PRO B CD  1 
ATOM   9912  N N   . CYS B 1 517 ? 132.887 124.045 124.654 1.00 128.38 ? 537 CYS B N   1 
ATOM   9913  C CA  . CYS B 1 517 ? 131.925 124.851 125.386 1.00 129.91 ? 537 CYS B CA  1 
ATOM   9914  C C   . CYS B 1 517 ? 132.063 124.548 126.878 1.00 129.51 ? 537 CYS B C   1 
ATOM   9915  O O   . CYS B 1 517 ? 132.659 123.546 127.263 1.00 128.80 ? 537 CYS B O   1 
ATOM   9916  C CB  . CYS B 1 517 ? 130.510 124.601 124.878 1.00 131.11 ? 537 CYS B CB  1 
ATOM   9917  S SG  . CYS B 1 517 ? 129.367 125.966 125.225 1.00 135.59 ? 537 CYS B SG  1 
ATOM   9918  N N   . LYS B 1 518 ? 131.568 125.457 127.717 1.00 128.07 ? 538 LYS B N   1 
ATOM   9919  C CA  . LYS B 1 518 ? 131.783 125.366 129.152 1.00 127.37 ? 538 LYS B CA  1 
ATOM   9920  C C   . LYS B 1 518 ? 130.659 124.541 129.776 1.00 126.80 ? 538 LYS B C   1 
ATOM   9921  O O   . LYS B 1 518 ? 129.711 124.146 129.097 1.00 127.88 ? 538 LYS B O   1 
ATOM   9922  C CB  . LYS B 1 518 ? 131.873 126.763 129.775 1.00 128.71 ? 538 LYS B CB  1 
ATOM   9923  C CG  . LYS B 1 518 ? 132.679 127.775 128.975 1.00 131.31 ? 538 LYS B CG  1 
ATOM   9924  C CD  . LYS B 1 518 ? 132.884 129.096 129.682 1.00 133.04 ? 538 LYS B CD  1 
ATOM   9925  C CE  . LYS B 1 518 ? 134.197 129.771 129.338 1.00 133.50 ? 538 LYS B CE  1 
ATOM   9926  N NZ  . LYS B 1 518 ? 134.355 130.023 127.884 1.00 133.62 ? 538 LYS B NZ  1 
ATOM   9927  N N   . GLU B 1 519 ? 130.764 124.324 131.093 1.00 123.83 ? 539 GLU B N   1 
ATOM   9928  C CA  . GLU B 1 519 ? 129.913 123.388 131.805 1.00 121.09 ? 539 GLU B CA  1 
ATOM   9929  C C   . GLU B 1 519 ? 128.502 123.950 131.950 1.00 116.03 ? 539 GLU B C   1 
ATOM   9930  O O   . GLU B 1 519 ? 127.553 123.182 132.051 1.00 115.52 ? 539 GLU B O   1 
ATOM   9931  C CB  . GLU B 1 519 ? 130.502 123.062 133.179 1.00 122.86 ? 539 GLU B CB  1 
ATOM   9932  C CG  . GLU B 1 519 ? 131.872 122.406 133.108 1.00 125.19 ? 539 GLU B CG  1 
ATOM   9933  C CD  . GLU B 1 519 ? 133.054 123.344 132.913 1.00 128.29 ? 539 GLU B CD  1 
ATOM   9934  O OE1 . GLU B 1 519 ? 134.036 123.231 133.678 1.00 130.29 ? 539 GLU B OE1 1 
ATOM   9935  O OE2 . GLU B 1 519 ? 132.984 124.194 131.998 1.00 129.13 ? 539 GLU B OE2 1 
ATOM   9936  N N   . ASN B 1 520 ? 128.370 125.281 131.969 1.00 113.54 ? 540 ASN B N   1 
ATOM   9937  C CA  . ASN B 1 520 ? 127.069 125.913 132.124 1.00 115.24 ? 540 ASN B CA  1 
ATOM   9938  C C   . ASN B 1 520 ? 126.192 125.595 130.915 1.00 118.04 ? 540 ASN B C   1 
ATOM   9939  O O   . ASN B 1 520 ? 124.999 125.325 131.071 1.00 118.53 ? 540 ASN B O   1 
ATOM   9940  C CB  . ASN B 1 520 ? 127.192 127.429 132.316 1.00 116.26 ? 540 ASN B CB  1 
ATOM   9941  C CG  . ASN B 1 520 ? 125.880 128.112 132.653 1.00 118.81 ? 540 ASN B CG  1 
ATOM   9942  O OD1 . ASN B 1 520 ? 124.845 127.837 132.049 1.00 119.33 ? 540 ASN B OD1 1 
ATOM   9943  N ND2 . ASN B 1 520 ? 125.906 129.027 133.612 1.00 119.62 ? 540 ASN B ND2 1 
ATOM   9944  N N   . GLU B 1 521 ? 126.790 125.634 129.716 1.00 119.63 ? 541 GLU B N   1 
ATOM   9945  C CA  . GLU B 1 521 ? 126.013 125.697 128.485 1.00 119.69 ? 541 GLU B CA  1 
ATOM   9946  C C   . GLU B 1 521 ? 125.920 124.320 127.839 1.00 118.58 ? 541 GLU B C   1 
ATOM   9947  O O   . GLU B 1 521 ? 126.649 123.398 128.206 1.00 116.89 ? 541 GLU B O   1 
ATOM   9948  C CB  . GLU B 1 521 ? 126.626 126.657 127.462 1.00 121.81 ? 541 GLU B CB  1 
ATOM   9949  C CG  . GLU B 1 521 ? 127.141 127.964 128.033 1.00 124.38 ? 541 GLU B CG  1 
ATOM   9950  C CD  . GLU B 1 521 ? 128.624 127.896 128.350 1.00 126.28 ? 541 GLU B CD  1 
ATOM   9951  O OE1 . GLU B 1 521 ? 129.258 128.952 128.561 1.00 127.75 ? 541 GLU B OE1 1 
ATOM   9952  O OE2 . GLU B 1 521 ? 129.135 126.766 128.402 1.00 124.23 ? 541 GLU B OE2 1 
ATOM   9953  N N   . TYR B 1 522 ? 125.020 124.225 126.852 1.00 119.64 ? 542 TYR B N   1 
ATOM   9954  C CA  . TYR B 1 522 ? 124.825 123.021 126.064 1.00 120.98 ? 542 TYR B CA  1 
ATOM   9955  C C   . TYR B 1 522 ? 124.716 123.409 124.594 1.00 122.36 ? 542 TYR B C   1 
ATOM   9956  O O   . TYR B 1 522 ? 124.282 124.514 124.272 1.00 122.21 ? 542 TYR B O   1 
ATOM   9957  C CB  . TYR B 1 522 ? 123.572 122.264 126.512 1.00 120.90 ? 542 TYR B CB  1 
ATOM   9958  C CG  . TYR B 1 522 ? 122.275 122.926 126.117 1.00 122.70 ? 542 TYR B CG  1 
ATOM   9959  C CD1 . TYR B 1 522 ? 121.921 124.170 126.615 1.00 123.47 ? 542 TYR B CD1 1 
ATOM   9960  C CD2 . TYR B 1 522 ? 121.412 122.319 125.219 1.00 124.57 ? 542 TYR B CD2 1 
ATOM   9961  C CE1 . TYR B 1 522 ? 120.736 124.786 126.248 1.00 124.68 ? 542 TYR B CE1 1 
ATOM   9962  C CE2 . TYR B 1 522 ? 120.220 122.918 124.843 1.00 125.70 ? 542 TYR B CE2 1 
ATOM   9963  C CZ  . TYR B 1 522 ? 119.881 124.157 125.359 1.00 125.83 ? 542 TYR B CZ  1 
ATOM   9964  O OH  . TYR B 1 522 ? 118.702 124.752 124.984 1.00 126.56 ? 542 TYR B OH  1 
ATOM   9965  N N   . VAL B 1 523 ? 125.095 122.484 123.708 1.00 124.65 ? 543 VAL B N   1 
ATOM   9966  C CA  . VAL B 1 523 ? 125.089 122.732 122.274 1.00 125.80 ? 543 VAL B CA  1 
ATOM   9967  C C   . VAL B 1 523 ? 123.648 122.728 121.769 1.00 128.82 ? 543 VAL B C   1 
ATOM   9968  O O   . VAL B 1 523 ? 122.967 121.706 121.834 1.00 130.31 ? 543 VAL B O   1 
ATOM   9969  C CB  . VAL B 1 523 ? 125.966 121.715 121.517 1.00 123.66 ? 543 VAL B CB  1 
ATOM   9970  C CG1 . VAL B 1 523 ? 127.442 122.053 121.646 1.00 122.73 ? 543 VAL B CG1 1 
ATOM   9971  C CG2 . VAL B 1 523 ? 125.703 120.276 121.946 1.00 123.14 ? 543 VAL B CG2 1 
ATOM   9972  N N   . PHE B 1 524 ? 123.194 123.882 121.264 1.00 132.01 ? 544 PHE B N   1 
ATOM   9973  C CA  . PHE B 1 524 ? 121.826 124.006 120.784 1.00 135.80 ? 544 PHE B CA  1 
ATOM   9974  C C   . PHE B 1 524 ? 121.772 123.568 119.323 1.00 136.32 ? 544 PHE B C   1 
ATOM   9975  O O   . PHE B 1 524 ? 121.044 122.640 118.983 1.00 137.00 ? 544 PHE B O   1 
ATOM   9976  C CB  . PHE B 1 524 ? 121.309 125.430 120.994 1.00 139.91 ? 544 PHE B CB  1 
ATOM   9977  C CG  . PHE B 1 524 ? 119.867 125.668 120.619 1.00 145.50 ? 544 PHE B CG  1 
ATOM   9978  C CD1 . PHE B 1 524 ? 118.955 124.626 120.505 1.00 148.56 ? 544 PHE B CD1 1 
ATOM   9979  C CD2 . PHE B 1 524 ? 119.420 126.958 120.377 1.00 148.25 ? 544 PHE B CD2 1 
ATOM   9980  C CE1 . PHE B 1 524 ? 117.634 124.872 120.162 1.00 151.18 ? 544 PHE B CE1 1 
ATOM   9981  C CE2 . PHE B 1 524 ? 118.099 127.202 120.032 1.00 150.74 ? 544 PHE B CE2 1 
ATOM   9982  C CZ  . PHE B 1 524 ? 117.208 126.159 119.925 1.00 151.88 ? 544 PHE B CZ  1 
ATOM   9983  N N   . ASP B 1 525 ? 122.536 124.262 118.474 1.00 136.80 ? 545 ASP B N   1 
ATOM   9984  C CA  . ASP B 1 525 ? 122.867 123.800 117.135 1.00 137.03 ? 545 ASP B CA  1 
ATOM   9985  C C   . ASP B 1 525 ? 124.388 123.774 117.049 1.00 133.58 ? 545 ASP B C   1 
ATOM   9986  O O   . ASP B 1 525 ? 125.050 124.584 117.695 1.00 133.13 ? 545 ASP B O   1 
ATOM   9987  C CB  . ASP B 1 525 ? 122.269 124.694 116.044 1.00 139.43 ? 545 ASP B CB  1 
ATOM   9988  C CG  . ASP B 1 525 ? 122.519 126.170 116.291 1.00 141.01 ? 545 ASP B CG  1 
ATOM   9989  O OD1 . ASP B 1 525 ? 122.030 126.667 117.324 1.00 142.10 ? 545 ASP B OD1 1 
ATOM   9990  O OD2 . ASP B 1 525 ? 123.209 126.803 115.462 1.00 141.74 ? 545 ASP B OD2 1 
ATOM   9991  N N   . GLU B 1 526 ? 124.933 122.865 116.234 1.00 131.46 ? 546 GLU B N   1 
ATOM   9992  C CA  . GLU B 1 526 ? 126.344 122.515 116.296 1.00 130.93 ? 546 GLU B CA  1 
ATOM   9993  C C   . GLU B 1 526 ? 127.242 123.752 116.206 1.00 125.25 ? 546 GLU B C   1 
ATOM   9994  O O   . GLU B 1 526 ? 128.406 123.688 116.596 1.00 123.65 ? 546 GLU B O   1 
ATOM   9995  C CB  . GLU B 1 526 ? 126.687 121.514 115.189 1.00 135.01 ? 546 GLU B CB  1 
ATOM   9996  C CG  . GLU B 1 526 ? 127.985 120.765 115.436 1.00 138.97 ? 546 GLU B CG  1 
ATOM   9997  C CD  . GLU B 1 526 ? 128.019 119.956 116.723 1.00 141.74 ? 546 GLU B CD  1 
ATOM   9998  O OE1 . GLU B 1 526 ? 129.131 119.644 117.193 1.00 142.72 ? 546 GLU B OE1 1 
ATOM   9999  O OE2 . GLU B 1 526 ? 126.934 119.626 117.245 1.00 143.09 ? 546 GLU B OE2 1 
ATOM   10000 N N   . TYR B 1 527 ? 126.704 124.870 115.706 1.00 123.69 ? 547 TYR B N   1 
ATOM   10001 C CA  . TYR B 1 527 ? 127.481 126.089 115.561 1.00 125.67 ? 547 TYR B CA  1 
ATOM   10002 C C   . TYR B 1 527 ? 127.329 127.010 116.770 1.00 125.16 ? 547 TYR B C   1 
ATOM   10003 O O   . TYR B 1 527 ? 128.097 127.965 116.885 1.00 122.96 ? 547 TYR B O   1 
ATOM   10004 C CB  . TYR B 1 527 ? 127.096 126.794 114.260 1.00 129.33 ? 547 TYR B CB  1 
ATOM   10005 C CG  . TYR B 1 527 ? 127.353 125.962 113.030 1.00 131.37 ? 547 TYR B CG  1 
ATOM   10006 C CD1 . TYR B 1 527 ? 128.646 125.714 112.591 1.00 130.81 ? 547 TYR B CD1 1 
ATOM   10007 C CD2 . TYR B 1 527 ? 126.307 125.400 112.315 1.00 133.53 ? 547 TYR B CD2 1 
ATOM   10008 C CE1 . TYR B 1 527 ? 128.894 124.947 111.462 1.00 131.65 ? 547 TYR B CE1 1 
ATOM   10009 C CE2 . TYR B 1 527 ? 126.536 124.621 111.194 1.00 134.43 ? 547 TYR B CE2 1 
ATOM   10010 C CZ  . TYR B 1 527 ? 127.832 124.392 110.767 1.00 133.72 ? 547 TYR B CZ  1 
ATOM   10011 O OH  . TYR B 1 527 ? 128.030 123.620 109.652 1.00 134.45 ? 547 TYR B OH  1 
ATOM   10012 N N   . THR B 1 528 ? 126.352 126.741 117.651 1.00 127.18 ? 548 THR B N   1 
ATOM   10013 C CA  . THR B 1 528 ? 126.131 127.581 118.818 1.00 129.34 ? 548 THR B CA  1 
ATOM   10014 C C   . THR B 1 528 ? 125.817 126.734 120.051 1.00 129.88 ? 548 THR B C   1 
ATOM   10015 O O   . THR B 1 528 ? 124.993 125.819 119.992 1.00 129.91 ? 548 THR B O   1 
ATOM   10016 C CB  . THR B 1 528 ? 125.001 128.592 118.583 1.00 131.15 ? 548 THR B CB  1 
ATOM   10017 O OG1 . THR B 1 528 ? 123.802 127.869 118.317 1.00 132.83 ? 548 THR B OG1 1 
ATOM   10018 C CG2 . THR B 1 528 ? 125.272 129.551 117.444 1.00 130.80 ? 548 THR B CG2 1 
ATOM   10019 N N   . CYS B 1 529 ? 126.438 127.095 121.179 1.00 131.46 ? 549 CYS B N   1 
ATOM   10020 C CA  . CYS B 1 529 ? 126.099 126.515 122.465 1.00 132.57 ? 549 CYS B CA  1 
ATOM   10021 C C   . CYS B 1 529 ? 125.683 127.637 123.413 1.00 133.62 ? 549 CYS B C   1 
ATOM   10022 O O   . CYS B 1 529 ? 126.354 128.662 123.502 1.00 130.35 ? 549 CYS B O   1 
ATOM   10023 C CB  . CYS B 1 529 ? 127.248 125.694 123.038 1.00 131.71 ? 549 CYS B CB  1 
ATOM   10024 S SG  . CYS B 1 529 ? 128.755 126.638 123.394 1.00 131.64 ? 549 CYS B SG  1 
ATOM   10025 N N   . LYS B 1 530 ? 124.540 127.440 124.078 1.00 138.03 ? 550 LYS B N   1 
ATOM   10026 C CA  . LYS B 1 530 ? 123.941 128.470 124.906 1.00 142.59 ? 550 LYS B CA  1 
ATOM   10027 C C   . LYS B 1 530 ? 123.779 127.950 126.330 1.00 144.06 ? 550 LYS B C   1 
ATOM   10028 O O   . LYS B 1 530 ? 123.605 126.745 126.556 1.00 142.43 ? 550 LYS B O   1 
ATOM   10029 C CB  . LYS B 1 530 ? 122.595 128.900 124.321 1.00 146.06 ? 550 LYS B CB  1 
ATOM   10030 C CG  . LYS B 1 530 ? 121.732 129.764 125.234 1.00 148.77 ? 550 LYS B CG  1 
ATOM   10031 C CD  . LYS B 1 530 ? 120.455 130.251 124.580 1.00 151.61 ? 550 LYS B CD  1 
ATOM   10032 C CE  . LYS B 1 530 ? 119.406 129.169 124.418 1.00 152.69 ? 550 LYS B CE  1 
ATOM   10033 N NZ  . LYS B 1 530 ? 118.838 128.749 125.722 1.00 152.52 ? 550 LYS B NZ  1 
ATOM   10034 N N   . ALA B 1 531 ? 123.837 128.902 127.269 1.00 146.12 ? 551 ALA B N   1 
ATOM   10035 C CA  . ALA B 1 531 ? 123.715 128.624 128.688 1.00 147.26 ? 551 ALA B CA  1 
ATOM   10036 C C   . ALA B 1 531 ? 122.240 128.468 129.045 1.00 149.89 ? 551 ALA B C   1 
ATOM   10037 O O   . ALA B 1 531 ? 121.400 129.248 128.599 1.00 149.82 ? 551 ALA B O   1 
ATOM   10038 C CB  . ALA B 1 531 ? 124.346 129.738 129.485 1.00 146.92 ? 551 ALA B CB  1 
ATOM   10039 N N   . CYS B 1 532 ? 121.941 127.445 129.851 1.00 152.10 ? 552 CYS B N   1 
ATOM   10040 C CA  . CYS B 1 532 ? 120.588 127.209 130.325 1.00 155.23 ? 552 CYS B CA  1 
ATOM   10041 C C   . CYS B 1 532 ? 120.345 128.085 131.554 1.00 154.39 ? 552 CYS B C   1 
ATOM   10042 O O   . CYS B 1 532 ? 121.160 128.950 131.875 1.00 152.63 ? 552 CYS B O   1 
ATOM   10043 C CB  . CYS B 1 532 ? 120.349 125.714 130.541 1.00 158.11 ? 552 CYS B CB  1 
ATOM   10044 S SG  . CYS B 1 532 ? 121.755 124.807 131.241 1.00 159.96 ? 552 CYS B SG  1 
ATOM   10045 N N   . GLN B 1 533 ? 119.216 127.865 132.238 1.00 156.06 ? 553 GLN B N   1 
ATOM   10046 C CA  . GLN B 1 533 ? 118.740 128.777 133.267 1.00 157.37 ? 553 GLN B CA  1 
ATOM   10047 C C   . GLN B 1 533 ? 119.692 128.739 134.462 1.00 155.10 ? 553 GLN B C   1 
ATOM   10048 O O   . GLN B 1 533 ? 120.674 127.996 134.469 1.00 156.13 ? 553 GLN B O   1 
ATOM   10049 C CB  . GLN B 1 533 ? 117.306 128.438 133.702 1.00 160.75 ? 553 GLN B CB  1 
ATOM   10050 C CG  . GLN B 1 533 ? 116.390 127.890 132.603 1.00 162.88 ? 553 GLN B CG  1 
ATOM   10051 C CD  . GLN B 1 533 ? 116.505 128.616 131.282 1.00 164.85 ? 553 GLN B CD  1 
ATOM   10052 O OE1 . GLN B 1 533 ? 116.438 129.841 131.224 1.00 165.35 ? 553 GLN B OE1 1 
ATOM   10053 N NE2 . GLN B 1 533 ? 116.708 127.865 130.208 1.00 165.42 ? 553 GLN B NE2 1 
ATOM   10054 N N   . LEU B 1 534 ? 119.392 129.552 135.478 1.00 151.76 ? 554 LEU B N   1 
ATOM   10055 C CA  . LEU B 1 534 ? 120.196 129.569 136.693 1.00 148.93 ? 554 LEU B CA  1 
ATOM   10056 C C   . LEU B 1 534 ? 120.173 128.187 137.345 1.00 140.62 ? 554 LEU B C   1 
ATOM   10057 O O   . LEU B 1 534 ? 121.222 127.652 137.691 1.00 139.03 ? 554 LEU B O   1 
ATOM   10058 C CB  . LEU B 1 534 ? 119.675 130.640 137.660 1.00 154.63 ? 554 LEU B CB  1 
ATOM   10059 C CG  . LEU B 1 534 ? 120.293 132.032 137.522 1.00 160.42 ? 554 LEU B CG  1 
ATOM   10060 C CD1 . LEU B 1 534 ? 121.804 131.980 137.709 1.00 161.29 ? 554 LEU B CD1 1 
ATOM   10061 C CD2 . LEU B 1 534 ? 119.940 132.664 136.182 1.00 162.25 ? 554 LEU B CD2 1 
ATOM   10062 N N   . GLY B 1 535 ? 118.972 127.615 137.497 1.00 134.08 ? 555 GLY B N   1 
ATOM   10063 C CA  . GLY B 1 535 ? 118.810 126.291 138.074 1.00 130.37 ? 555 GLY B CA  1 
ATOM   10064 C C   . GLY B 1 535 ? 118.690 125.214 136.999 1.00 128.62 ? 555 GLY B C   1 
ATOM   10065 O O   . GLY B 1 535 ? 117.642 124.587 136.858 1.00 130.14 ? 555 GLY B O   1 
ATOM   10066 N N   . SER B 1 536 ? 119.769 125.007 136.242 1.00 126.29 ? 556 SER B N   1 
ATOM   10067 C CA  . SER B 1 536 ? 119.769 124.013 135.179 1.00 124.41 ? 556 SER B CA  1 
ATOM   10068 C C   . SER B 1 536 ? 121.180 123.486 134.953 1.00 120.52 ? 556 SER B C   1 
ATOM   10069 O O   . SER B 1 536 ? 122.156 124.148 135.300 1.00 118.70 ? 556 SER B O   1 
ATOM   10070 C CB  . SER B 1 536 ? 119.183 124.564 133.904 1.00 125.52 ? 556 SER B CB  1 
ATOM   10071 O OG  . SER B 1 536 ? 119.807 125.788 133.554 1.00 125.59 ? 556 SER B OG  1 
ATOM   10072 N N   . TRP B 1 537 ? 121.262 122.285 134.364 1.00 117.12 ? 557 TRP B N   1 
ATOM   10073 C CA  . TRP B 1 537 ? 122.533 121.635 134.091 1.00 114.95 ? 557 TRP B CA  1 
ATOM   10074 C C   . TRP B 1 537 ? 122.414 120.795 132.823 1.00 118.65 ? 557 TRP B C   1 
ATOM   10075 O O   . TRP B 1 537 ? 121.408 120.120 132.622 1.00 120.06 ? 557 TRP B O   1 
ATOM   10076 C CB  . TRP B 1 537 ? 122.971 120.764 135.276 1.00 111.96 ? 557 TRP B CB  1 
ATOM   10077 C CG  . TRP B 1 537 ? 124.443 120.493 135.301 1.00 109.58 ? 557 TRP B CG  1 
ATOM   10078 C CD1 . TRP B 1 537 ? 125.070 119.295 135.122 1.00 109.05 ? 557 TRP B CD1 1 
ATOM   10079 C CD2 . TRP B 1 537 ? 125.482 121.461 135.523 1.00 107.31 ? 557 TRP B CD2 1 
ATOM   10080 N NE1 . TRP B 1 537 ? 126.427 119.451 135.211 1.00 108.51 ? 557 TRP B NE1 1 
ATOM   10081 C CE2 . TRP B 1 537 ? 126.711 120.769 135.457 1.00 107.57 ? 557 TRP B CE2 1 
ATOM   10082 C CE3 . TRP B 1 537 ? 125.491 122.840 135.763 1.00 105.12 ? 557 TRP B CE3 1 
ATOM   10083 C CZ2 . TRP B 1 537 ? 127.936 121.415 135.624 1.00 106.16 ? 557 TRP B CZ2 1 
ATOM   10084 C CZ3 . TRP B 1 537 ? 126.703 123.474 135.923 1.00 104.43 ? 557 TRP B CZ3 1 
ATOM   10085 C CH2 . TRP B 1 537 ? 127.907 122.769 135.874 1.00 104.85 ? 557 TRP B CH2 1 
ATOM   10086 N N   . PRO B 1 538 ? 123.443 120.774 131.945 1.00 124.31 ? 558 PRO B N   1 
ATOM   10087 C CA  . PRO B 1 538 ? 123.423 119.918 130.759 1.00 130.29 ? 558 PRO B CA  1 
ATOM   10088 C C   . PRO B 1 538 ? 123.397 118.433 131.119 1.00 139.39 ? 558 PRO B C   1 
ATOM   10089 O O   . PRO B 1 538 ? 123.963 118.023 132.131 1.00 139.82 ? 558 PRO B O   1 
ATOM   10090 C CB  . PRO B 1 538 ? 124.717 120.277 130.012 1.00 128.04 ? 558 PRO B CB  1 
ATOM   10091 C CG  . PRO B 1 538 ? 125.616 120.858 131.081 1.00 125.43 ? 558 PRO B CG  1 
ATOM   10092 C CD  . PRO B 1 538 ? 124.683 121.559 132.047 1.00 124.23 ? 558 PRO B CD  1 
ATOM   10093 N N   . THR B 1 539 ? 122.722 117.645 130.277 1.00 149.83 ? 559 THR B N   1 
ATOM   10094 C CA  . THR B 1 539 ? 122.587 116.212 130.481 1.00 158.79 ? 559 THR B CA  1 
ATOM   10095 C C   . THR B 1 539 ? 123.849 115.510 129.984 1.00 164.17 ? 559 THR B C   1 
ATOM   10096 O O   . THR B 1 539 ? 124.803 116.155 129.558 1.00 162.91 ? 559 THR B O   1 
ATOM   10097 C CB  . THR B 1 539 ? 121.314 115.690 129.799 1.00 161.06 ? 559 THR B CB  1 
ATOM   10098 O OG1 . THR B 1 539 ? 121.339 116.085 128.427 1.00 160.44 ? 559 THR B OG1 1 
ATOM   10099 C CG2 . THR B 1 539 ? 120.050 116.198 130.457 1.00 161.40 ? 559 THR B CG2 1 
ATOM   10100 N N   . ASP B 1 540 ? 123.844 114.173 130.044 1.00 173.29 ? 560 ASP B N   1 
ATOM   10101 C CA  . ASP B 1 540 ? 124.925 113.367 129.501 1.00 182.31 ? 560 ASP B CA  1 
ATOM   10102 C C   . ASP B 1 540 ? 124.965 113.524 127.982 1.00 184.18 ? 560 ASP B C   1 
ATOM   10103 O O   . ASP B 1 540 ? 123.926 113.599 127.324 1.00 183.27 ? 560 ASP B O   1 
ATOM   10104 C CB  . ASP B 1 540 ? 124.766 111.894 129.886 1.00 190.49 ? 560 ASP B CB  1 
ATOM   10105 C CG  . ASP B 1 540 ? 123.532 111.248 129.279 1.00 197.25 ? 560 ASP B CG  1 
ATOM   10106 O OD1 . ASP B 1 540 ? 122.416 111.714 129.587 1.00 198.00 ? 560 ASP B OD1 1 
ATOM   10107 O OD2 . ASP B 1 540 ? 123.696 110.299 128.487 1.00 201.03 ? 560 ASP B OD2 1 
ATOM   10108 N N   . ASP B 1 541 ? 126.194 113.554 127.440 1.00 186.07 ? 561 ASP B N   1 
ATOM   10109 C CA  . ASP B 1 541 ? 126.468 113.703 126.016 1.00 188.38 ? 561 ASP B CA  1 
ATOM   10110 C C   . ASP B 1 541 ? 125.994 115.060 125.483 1.00 182.61 ? 561 ASP B C   1 
ATOM   10111 O O   . ASP B 1 541 ? 125.956 115.267 124.272 1.00 181.59 ? 561 ASP B O   1 
ATOM   10112 C CB  . ASP B 1 541 ? 125.911 112.516 125.226 1.00 195.46 ? 561 ASP B CB  1 
ATOM   10113 C CG  . ASP B 1 541 ? 126.675 111.220 125.452 1.00 202.33 ? 561 ASP B CG  1 
ATOM   10114 O OD1 . ASP B 1 541 ? 127.799 111.271 126.001 1.00 204.89 ? 561 ASP B OD1 1 
ATOM   10115 O OD2 . ASP B 1 541 ? 126.136 110.165 125.079 1.00 205.67 ? 561 ASP B OD2 1 
ATOM   10116 N N   . LEU B 1 542 ? 125.670 115.987 126.396 1.00 177.55 ? 562 LEU B N   1 
ATOM   10117 C CA  . LEU B 1 542 ? 125.388 117.382 126.095 1.00 173.19 ? 562 LEU B CA  1 
ATOM   10118 C C   . LEU B 1 542 ? 124.169 117.547 125.185 1.00 172.99 ? 562 LEU B C   1 
ATOM   10119 O O   . LEU B 1 542 ? 124.064 118.532 124.451 1.00 171.23 ? 562 LEU B O   1 
ATOM   10120 C CB  . LEU B 1 542 ? 126.645 118.008 125.482 1.00 170.29 ? 562 LEU B CB  1 
ATOM   10121 C CG  . LEU B 1 542 ? 126.740 119.526 125.614 1.00 168.03 ? 562 LEU B CG  1 
ATOM   10122 C CD1 . LEU B 1 542 ? 126.423 119.967 127.033 1.00 166.20 ? 562 LEU B CD1 1 
ATOM   10123 C CD2 . LEU B 1 542 ? 128.120 120.014 125.216 1.00 168.57 ? 562 LEU B CD2 1 
ATOM   10124 N N   . THR B 1 543 ? 123.221 116.609 125.284 1.00 174.52 ? 563 THR B N   1 
ATOM   10125 C CA  . THR B 1 543 ? 122.031 116.632 124.448 1.00 177.01 ? 563 THR B CA  1 
ATOM   10126 C C   . THR B 1 543 ? 121.140 117.818 124.816 1.00 175.19 ? 563 THR B C   1 
ATOM   10127 O O   . THR B 1 543 ? 120.558 118.437 123.929 1.00 172.42 ? 563 THR B O   1 
ATOM   10128 C CB  . THR B 1 543 ? 121.269 115.304 124.536 1.00 180.87 ? 563 THR B CB  1 
ATOM   10129 O OG1 . THR B 1 543 ? 120.967 115.050 125.909 1.00 180.67 ? 563 THR B OG1 1 
ATOM   10130 C CG2 . THR B 1 543 ? 122.051 114.144 123.962 1.00 182.74 ? 563 THR B CG2 1 
ATOM   10131 N N   . GLY B 1 544 ? 121.045 118.136 126.115 1.00 174.64 ? 564 GLY B N   1 
ATOM   10132 C CA  . GLY B 1 544 ? 120.214 119.236 126.576 1.00 172.15 ? 564 GLY B CA  1 
ATOM   10133 C C   . GLY B 1 544 ? 120.424 119.552 128.056 1.00 167.82 ? 564 GLY B C   1 
ATOM   10134 O O   . GLY B 1 544 ? 121.098 118.817 128.773 1.00 163.92 ? 564 GLY B O   1 
ATOM   10135 N N   . CYS B 1 545 ? 119.830 120.666 128.494 1.00 165.65 ? 565 CYS B N   1 
ATOM   10136 C CA  . CYS B 1 545 ? 119.901 121.104 129.881 1.00 164.66 ? 565 CYS B CA  1 
ATOM   10137 C C   . CYS B 1 545 ? 118.602 120.755 130.607 1.00 164.72 ? 565 CYS B C   1 
ATOM   10138 O O   . CYS B 1 545 ? 117.527 121.167 130.181 1.00 163.83 ? 565 CYS B O   1 
ATOM   10139 C CB  . CYS B 1 545 ? 120.116 122.612 129.959 1.00 164.85 ? 565 CYS B CB  1 
ATOM   10140 S SG  . CYS B 1 545 ? 121.848 123.131 130.085 1.00 163.24 ? 565 CYS B SG  1 
ATOM   10141 N N   . ASP B 1 546 ? 118.725 119.973 131.686 1.00 165.78 ? 566 ASP B N   1 
ATOM   10142 C CA  . ASP B 1 546 ? 117.603 119.583 132.524 1.00 167.22 ? 566 ASP B CA  1 
ATOM   10143 C C   . ASP B 1 546 ? 117.673 120.366 133.835 1.00 167.37 ? 566 ASP B C   1 
ATOM   10144 O O   . ASP B 1 546 ? 118.570 121.184 134.033 1.00 164.05 ? 566 ASP B O   1 
ATOM   10145 C CB  . ASP B 1 546 ? 117.623 118.071 132.775 1.00 166.71 ? 566 ASP B CB  1 
ATOM   10146 C CG  . ASP B 1 546 ? 118.682 117.635 133.772 1.00 166.29 ? 566 ASP B CG  1 
ATOM   10147 O OD1 . ASP B 1 546 ? 119.885 117.789 133.473 1.00 166.37 ? 566 ASP B OD1 1 
ATOM   10148 O OD2 . ASP B 1 546 ? 118.288 117.187 134.861 1.00 164.90 ? 566 ASP B OD2 1 
ATOM   10149 N N   . LEU B 1 547 ? 116.740 120.066 134.745 1.00 168.82 ? 567 LEU B N   1 
ATOM   10150 C CA  . LEU B 1 547 ? 116.637 120.758 136.017 1.00 169.24 ? 567 LEU B CA  1 
ATOM   10151 C C   . LEU B 1 547 ? 117.556 120.096 137.042 1.00 167.85 ? 567 LEU B C   1 
ATOM   10152 O O   . LEU B 1 547 ? 117.589 118.872 137.148 1.00 165.46 ? 567 LEU B O   1 
ATOM   10153 C CB  . LEU B 1 547 ? 115.170 120.724 136.468 1.00 170.97 ? 567 LEU B CB  1 
ATOM   10154 C CG  . LEU B 1 547 ? 114.700 121.941 137.264 1.00 171.88 ? 567 LEU B CG  1 
ATOM   10155 C CD1 . LEU B 1 547 ? 114.590 123.164 136.364 1.00 171.36 ? 567 LEU B CD1 1 
ATOM   10156 C CD2 . LEU B 1 547 ? 113.371 121.663 137.951 1.00 173.08 ? 567 LEU B CD2 1 
ATOM   10157 N N   . ILE B 1 548 ? 118.246 120.929 137.831 1.00 165.42 ? 568 ILE B N   1 
ATOM   10158 C CA  . ILE B 1 548 ? 119.174 120.452 138.844 1.00 163.37 ? 568 ILE B CA  1 
ATOM   10159 C C   . ILE B 1 548 ? 118.369 119.800 139.968 1.00 164.48 ? 568 ILE B C   1 
ATOM   10160 O O   . ILE B 1 548 ? 117.354 120.345 140.400 1.00 164.61 ? 568 ILE B O   1 
ATOM   10161 C CB  . ILE B 1 548 ? 120.065 121.587 139.400 1.00 159.82 ? 568 ILE B CB  1 
ATOM   10162 C CG1 . ILE B 1 548 ? 120.537 122.558 138.315 1.00 156.79 ? 568 ILE B CG1 1 
ATOM   10163 C CG2 . ILE B 1 548 ? 121.242 121.011 140.177 1.00 160.51 ? 568 ILE B CG2 1 
ATOM   10164 C CD1 . ILE B 1 548 ? 121.286 123.761 138.846 1.00 155.39 ? 568 ILE B CD1 1 
ATOM   10165 N N   . PRO B 1 549 ? 118.793 118.622 140.486 1.00 165.25 ? 569 PRO B N   1 
ATOM   10166 C CA  . PRO B 1 549 ? 118.199 118.063 141.701 1.00 166.17 ? 569 PRO B CA  1 
ATOM   10167 C C   . PRO B 1 549 ? 118.357 119.013 142.887 1.00 167.43 ? 569 PRO B C   1 
ATOM   10168 O O   . PRO B 1 549 ? 119.359 119.718 142.996 1.00 168.15 ? 569 PRO B O   1 
ATOM   10169 C CB  . PRO B 1 549 ? 118.981 116.762 141.946 1.00 165.29 ? 569 PRO B CB  1 
ATOM   10170 C CG  . PRO B 1 549 ? 119.598 116.427 140.602 1.00 165.37 ? 569 PRO B CG  1 
ATOM   10171 C CD  . PRO B 1 549 ? 119.857 117.764 139.939 1.00 164.22 ? 569 PRO B CD  1 
ATOM   10172 N N   . VAL B 1 550 ? 117.360 119.012 143.777 1.00 167.81 ? 570 VAL B N   1 
ATOM   10173 C CA  . VAL B 1 550 ? 117.409 119.824 144.982 1.00 168.44 ? 570 VAL B CA  1 
ATOM   10174 C C   . VAL B 1 550 ? 117.987 118.980 146.115 1.00 172.49 ? 570 VAL B C   1 
ATOM   10175 O O   . VAL B 1 550 ? 117.524 117.866 146.352 1.00 172.46 ? 570 VAL B O   1 
ATOM   10176 C CB  . VAL B 1 550 ? 116.027 120.405 145.341 1.00 166.03 ? 570 VAL B CB  1 
ATOM   10177 C CG1 . VAL B 1 550 ? 115.685 121.604 144.471 1.00 164.93 ? 570 VAL B CG1 1 
ATOM   10178 C CG2 . VAL B 1 550 ? 114.920 119.364 145.273 1.00 166.51 ? 570 VAL B CG2 1 
ATOM   10179 N N   . GLN B 1 551 ? 119.008 119.523 146.796 1.00 174.89 ? 571 GLN B N   1 
ATOM   10180 C CA  . GLN B 1 551 ? 119.661 118.831 147.896 1.00 175.60 ? 571 GLN B CA  1 
ATOM   10181 C C   . GLN B 1 551 ? 119.126 119.387 149.215 1.00 174.60 ? 571 GLN B C   1 
ATOM   10182 O O   . GLN B 1 551 ? 119.739 120.243 149.849 1.00 173.59 ? 571 GLN B O   1 
ATOM   10183 C CB  . GLN B 1 551 ? 121.184 118.948 147.799 1.00 177.99 ? 571 GLN B CB  1 
ATOM   10184 C CG  . GLN B 1 551 ? 121.760 118.456 146.479 1.00 181.72 ? 571 GLN B CG  1 
ATOM   10185 C CD  . GLN B 1 551 ? 123.267 118.563 146.432 1.00 185.60 ? 571 GLN B CD  1 
ATOM   10186 O OE1 . GLN B 1 551 ? 123.914 118.965 147.398 1.00 185.46 ? 571 GLN B OE1 1 
ATOM   10187 N NE2 . GLN B 1 551 ? 123.843 118.200 145.297 1.00 187.51 ? 571 GLN B NE2 1 
ATOM   10188 N N   . TYR B 1 552 ? 117.969 118.858 149.623 1.00 173.52 ? 572 TYR B N   1 
ATOM   10189 C CA  . TYR B 1 552 ? 117.265 119.334 150.802 1.00 171.19 ? 572 TYR B CA  1 
ATOM   10190 C C   . TYR B 1 552 ? 118.004 118.892 152.064 1.00 169.30 ? 572 TYR B C   1 
ATOM   10191 O O   . TYR B 1 552 ? 119.019 118.198 152.005 1.00 169.99 ? 572 TYR B O   1 
ATOM   10192 C CB  . TYR B 1 552 ? 115.815 118.837 150.807 1.00 171.11 ? 572 TYR B CB  1 
ATOM   10193 C CG  . TYR B 1 552 ? 115.663 117.344 150.658 1.00 171.76 ? 572 TYR B CG  1 
ATOM   10194 C CD1 . TYR B 1 552 ? 115.723 116.742 149.411 1.00 173.98 ? 572 TYR B CD1 1 
ATOM   10195 C CD2 . TYR B 1 552 ? 115.484 116.526 151.762 1.00 171.56 ? 572 TYR B CD2 1 
ATOM   10196 C CE1 . TYR B 1 552 ? 115.589 115.370 149.262 1.00 175.50 ? 572 TYR B CE1 1 
ATOM   10197 C CE2 . TYR B 1 552 ? 115.353 115.153 151.632 1.00 173.64 ? 572 TYR B CE2 1 
ATOM   10198 C CZ  . TYR B 1 552 ? 115.405 114.572 150.377 1.00 176.18 ? 572 TYR B CZ  1 
ATOM   10199 O OH  . TYR B 1 552 ? 115.273 113.211 150.241 1.00 177.47 ? 572 TYR B OH  1 
ATOM   10200 N N   . LEU B 1 553 ? 117.462 119.310 153.209 1.00 167.40 ? 573 LEU B N   1 
ATOM   10201 C CA  . LEU B 1 553 ? 117.975 118.895 154.504 1.00 167.65 ? 573 LEU B CA  1 
ATOM   10202 C C   . LEU B 1 553 ? 117.276 117.598 154.897 1.00 165.06 ? 573 LEU B C   1 
ATOM   10203 O O   . LEU B 1 553 ? 116.223 117.622 155.532 1.00 164.10 ? 573 LEU B O   1 
ATOM   10204 C CB  . LEU B 1 553 ? 117.743 119.999 155.541 1.00 172.62 ? 573 LEU B CB  1 
ATOM   10205 C CG  . LEU B 1 553 ? 118.802 121.100 155.567 1.00 180.30 ? 573 LEU B CG  1 
ATOM   10206 C CD1 . LEU B 1 553 ? 118.751 121.934 154.295 1.00 183.57 ? 573 LEU B CD1 1 
ATOM   10207 C CD2 . LEU B 1 553 ? 118.637 121.985 156.794 1.00 180.49 ? 573 LEU B CD2 1 
ATOM   10208 N N   . ARG B 1 554 ? 117.881 116.470 154.505 1.00 167.01 ? 574 ARG B N   1 
ATOM   10209 C CA  . ARG B 1 554 ? 117.261 115.161 154.661 1.00 169.44 ? 574 ARG B CA  1 
ATOM   10210 C C   . ARG B 1 554 ? 117.291 114.732 156.128 1.00 163.20 ? 574 ARG B C   1 
ATOM   10211 O O   . ARG B 1 554 ? 118.167 115.143 156.888 1.00 162.98 ? 574 ARG B O   1 
ATOM   10212 C CB  . ARG B 1 554 ? 117.959 114.132 153.765 1.00 176.06 ? 574 ARG B CB  1 
ATOM   10213 C CG  . ARG B 1 554 ? 117.150 112.865 153.525 1.00 181.50 ? 574 ARG B CG  1 
ATOM   10214 C CD  . ARG B 1 554 ? 117.700 112.058 152.365 1.00 185.28 ? 574 ARG B CD  1 
ATOM   10215 N NE  . ARG B 1 554 ? 119.080 111.641 152.587 1.00 188.44 ? 574 ARG B NE  1 
ATOM   10216 C CZ  . ARG B 1 554 ? 119.807 110.917 151.738 1.00 191.28 ? 574 ARG B CZ  1 
ATOM   10217 N NH1 . ARG B 1 554 ? 119.289 110.503 150.593 1.00 192.37 ? 574 ARG B NH1 1 
ATOM   10218 N NH2 . ARG B 1 554 ? 121.055 110.604 152.042 1.00 191.29 ? 574 ARG B NH2 1 
ATOM   10219 N N   . TRP B 1 555 ? 116.306 113.904 156.502 1.00 155.60 ? 575 TRP B N   1 
ATOM   10220 C CA  . TRP B 1 555 ? 116.204 113.352 157.844 1.00 149.87 ? 575 TRP B CA  1 
ATOM   10221 C C   . TRP B 1 555 ? 117.373 112.420 158.148 1.00 150.52 ? 575 TRP B C   1 
ATOM   10222 O O   . TRP B 1 555 ? 117.703 112.215 159.317 1.00 149.14 ? 575 TRP B O   1 
ATOM   10223 C CB  . TRP B 1 555 ? 114.866 112.630 158.023 1.00 146.27 ? 575 TRP B CB  1 
ATOM   10224 C CG  . TRP B 1 555 ? 113.717 113.571 158.193 1.00 145.72 ? 575 TRP B CG  1 
ATOM   10225 C CD1 . TRP B 1 555 ? 112.969 114.160 157.213 1.00 146.99 ? 575 TRP B CD1 1 
ATOM   10226 C CD2 . TRP B 1 555 ? 113.222 114.088 159.439 1.00 144.98 ? 575 TRP B CD2 1 
ATOM   10227 N NE1 . TRP B 1 555 ? 112.023 114.982 157.765 1.00 145.71 ? 575 TRP B NE1 1 
ATOM   10228 C CE2 . TRP B 1 555 ? 112.148 114.950 159.129 1.00 145.37 ? 575 TRP B CE2 1 
ATOM   10229 C CE3 . TRP B 1 555 ? 113.560 113.890 160.783 1.00 145.47 ? 575 TRP B CE3 1 
ATOM   10230 C CZ2 . TRP B 1 555 ? 111.424 115.619 160.114 1.00 145.41 ? 575 TRP B CZ2 1 
ATOM   10231 C CZ3 . TRP B 1 555 ? 112.842 114.552 161.755 1.00 146.67 ? 575 TRP B CZ3 1 
ATOM   10232 C CH2 . TRP B 1 555 ? 111.790 115.406 161.423 1.00 146.72 ? 575 TRP B CH2 1 
ATOM   10233 N N   . GLY B 1 556 ? 117.969 111.833 157.101 1.00 153.49 ? 576 GLY B N   1 
ATOM   10234 C CA  . GLY B 1 556 ? 119.127 110.963 157.253 1.00 155.71 ? 576 GLY B CA  1 
ATOM   10235 C C   . GLY B 1 556 ? 120.385 111.743 157.629 1.00 158.06 ? 576 GLY B C   1 
ATOM   10236 O O   . GLY B 1 556 ? 120.297 112.888 158.068 1.00 157.57 ? 576 GLY B O   1 
ATOM   10237 N N   . ASP B 1 557 ? 121.544 111.089 157.484 1.00 163.25 ? 577 ASP B N   1 
ATOM   10238 C CA  . ASP B 1 557 ? 122.847 111.683 157.755 1.00 168.79 ? 577 ASP B CA  1 
ATOM   10239 C C   . ASP B 1 557 ? 123.028 111.883 159.261 1.00 171.88 ? 577 ASP B C   1 
ATOM   10240 O O   . ASP B 1 557 ? 122.060 112.114 159.982 1.00 171.00 ? 577 ASP B O   1 
ATOM   10241 C CB  . ASP B 1 557 ? 123.046 112.983 156.970 1.00 172.00 ? 577 ASP B CB  1 
ATOM   10242 C CG  . ASP B 1 557 ? 124.420 113.611 157.127 1.00 175.32 ? 577 ASP B CG  1 
ATOM   10243 O OD1 . ASP B 1 557 ? 124.661 114.244 158.173 1.00 175.55 ? 577 ASP B OD1 1 
ATOM   10244 O OD2 . ASP B 1 557 ? 125.244 113.446 156.207 1.00 176.31 ? 577 ASP B OD2 1 
ATOM   10245 N N   . PRO B 1 558 ? 124.270 111.768 159.793 1.00 177.87 ? 578 PRO B N   1 
ATOM   10246 C CA  . PRO B 1 558 ? 124.532 111.975 161.220 1.00 179.73 ? 578 PRO B CA  1 
ATOM   10247 C C   . PRO B 1 558 ? 123.975 113.243 161.868 1.00 176.31 ? 578 PRO B C   1 
ATOM   10248 O O   . PRO B 1 558 ? 123.441 113.167 162.968 1.00 174.88 ? 578 PRO B O   1 
ATOM   10249 C CB  . PRO B 1 558 ? 126.070 111.990 161.277 1.00 180.40 ? 578 PRO B CB  1 
ATOM   10250 C CG  . PRO B 1 558 ? 126.474 111.037 160.183 1.00 181.20 ? 578 PRO B CG  1 
ATOM   10251 C CD  . PRO B 1 558 ? 125.468 111.290 159.080 1.00 179.94 ? 578 PRO B CD  1 
ATOM   10252 N N   . GLU B 1 559 ? 124.072 114.391 161.187 1.00 171.12 ? 579 GLU B N   1 
ATOM   10253 C CA  . GLU B 1 559 ? 123.799 115.668 161.833 1.00 167.59 ? 579 GLU B CA  1 
ATOM   10254 C C   . GLU B 1 559 ? 122.318 115.785 162.202 1.00 159.16 ? 579 GLU B C   1 
ATOM   10255 O O   . GLU B 1 559 ? 121.989 116.073 163.351 1.00 158.97 ? 579 GLU B O   1 
ATOM   10256 C CB  . GLU B 1 559 ? 124.291 116.823 160.959 1.00 171.56 ? 579 GLU B CB  1 
ATOM   10257 C CG  . GLU B 1 559 ? 125.801 116.990 160.976 1.00 177.80 ? 579 GLU B CG  1 
ATOM   10258 C CD  . GLU B 1 559 ? 126.380 117.542 162.269 1.00 182.92 ? 579 GLU B CD  1 
ATOM   10259 O OE1 . GLU B 1 559 ? 125.594 117.865 163.186 1.00 183.11 ? 579 GLU B OE1 1 
ATOM   10260 O OE2 . GLU B 1 559 ? 127.620 117.652 162.356 1.00 185.83 ? 579 GLU B OE2 1 
ATOM   10261 N N   . PRO B 1 560 ? 121.361 115.583 161.268 1.00 151.33 ? 580 PRO B N   1 
ATOM   10262 C CA  . PRO B 1 560 ? 119.941 115.646 161.614 1.00 148.42 ? 580 PRO B CA  1 
ATOM   10263 C C   . PRO B 1 560 ? 119.509 114.575 162.613 1.00 148.48 ? 580 PRO B C   1 
ATOM   10264 O O   . PRO B 1 560 ? 118.667 114.840 163.464 1.00 144.67 ? 580 PRO B O   1 
ATOM   10265 C CB  . PRO B 1 560 ? 119.209 115.461 160.275 1.00 148.36 ? 580 PRO B CB  1 
ATOM   10266 C CG  . PRO B 1 560 ? 120.253 115.805 159.236 1.00 149.85 ? 580 PRO B CG  1 
ATOM   10267 C CD  . PRO B 1 560 ? 121.562 115.338 159.834 1.00 150.27 ? 580 PRO B CD  1 
ATOM   10268 N N   . ILE B 1 561 ? 120.101 113.377 162.517 1.00 151.64 ? 581 ILE B N   1 
ATOM   10269 C CA  . ILE B 1 561 ? 119.777 112.285 163.423 1.00 154.97 ? 581 ILE B CA  1 
ATOM   10270 C C   . ILE B 1 561 ? 120.183 112.673 164.847 1.00 151.80 ? 581 ILE B C   1 
ATOM   10271 O O   . ILE B 1 561 ? 119.443 112.429 165.797 1.00 155.11 ? 581 ILE B O   1 
ATOM   10272 C CB  . ILE B 1 561 ? 120.445 110.966 162.967 1.00 160.43 ? 581 ILE B CB  1 
ATOM   10273 C CG1 . ILE B 1 561 ? 119.875 110.444 161.641 1.00 165.29 ? 581 ILE B CG1 1 
ATOM   10274 C CG2 . ILE B 1 561 ? 120.374 109.903 164.055 1.00 160.28 ? 581 ILE B CG2 1 
ATOM   10275 C CD1 . ILE B 1 561 ? 118.442 109.954 161.712 1.00 167.43 ? 581 ILE B CD1 1 
ATOM   10276 N N   . ALA B 1 562 ? 121.367 113.278 164.989 1.00 145.41 ? 582 ALA B N   1 
ATOM   10277 C CA  . ALA B 1 562 ? 121.838 113.740 166.285 1.00 141.60 ? 582 ALA B CA  1 
ATOM   10278 C C   . ALA B 1 562 ? 120.912 114.833 166.815 1.00 136.24 ? 582 ALA B C   1 
ATOM   10279 O O   . ALA B 1 562 ? 120.591 114.844 168.000 1.00 135.98 ? 582 ALA B O   1 
ATOM   10280 C CB  . ALA B 1 562 ? 123.265 114.222 166.184 1.00 141.88 ? 582 ALA B CB  1 
ATOM   10281 N N   . ALA B 1 563 ? 120.476 115.737 165.930 1.00 133.81 ? 583 ALA B N   1 
ATOM   10282 C CA  . ALA B 1 563 ? 119.584 116.819 166.320 1.00 134.68 ? 583 ALA B CA  1 
ATOM   10283 C C   . ALA B 1 563 ? 118.271 116.254 166.867 1.00 137.23 ? 583 ALA B C   1 
ATOM   10284 O O   . ALA B 1 563 ? 117.779 116.711 167.898 1.00 139.87 ? 583 ALA B O   1 
ATOM   10285 C CB  . ALA B 1 563 ? 119.352 117.743 165.150 1.00 135.09 ? 583 ALA B CB  1 
ATOM   10286 N N   . VAL B 1 564 ? 117.722 115.244 166.182 1.00 137.07 ? 584 VAL B N   1 
ATOM   10287 C CA  . VAL B 1 564 ? 116.446 114.648 166.555 1.00 138.51 ? 584 VAL B CA  1 
ATOM   10288 C C   . VAL B 1 564 ? 116.606 113.883 167.869 1.00 135.91 ? 584 VAL B C   1 
ATOM   10289 O O   . VAL B 1 564 ? 115.690 113.866 168.689 1.00 134.47 ? 584 VAL B O   1 
ATOM   10290 C CB  . VAL B 1 564 ? 115.911 113.736 165.429 1.00 142.77 ? 584 VAL B CB  1 
ATOM   10291 C CG1 . VAL B 1 564 ? 114.703 112.910 165.852 1.00 145.36 ? 584 VAL B CG1 1 
ATOM   10292 C CG2 . VAL B 1 564 ? 115.602 114.525 164.165 1.00 143.54 ? 584 VAL B CG2 1 
ATOM   10293 N N   . VAL B 1 565 ? 117.768 113.240 168.053 1.00 136.34 ? 585 VAL B N   1 
ATOM   10294 C CA  . VAL B 1 565 ? 118.058 112.521 169.282 1.00 138.86 ? 585 VAL B CA  1 
ATOM   10295 C C   . VAL B 1 565 ? 118.021 113.503 170.450 1.00 138.27 ? 585 VAL B C   1 
ATOM   10296 O O   . VAL B 1 565 ? 117.409 113.220 171.477 1.00 137.75 ? 585 VAL B O   1 
ATOM   10297 C CB  . VAL B 1 565 ? 119.406 111.773 169.204 1.00 144.03 ? 585 VAL B CB  1 
ATOM   10298 C CG1 . VAL B 1 565 ? 120.006 111.506 170.579 1.00 145.79 ? 585 VAL B CG1 1 
ATOM   10299 C CG2 . VAL B 1 565 ? 119.285 110.477 168.416 1.00 146.09 ? 585 VAL B CG2 1 
ATOM   10300 N N   . PHE B 1 566 ? 118.688 114.652 170.289 1.00 139.63 ? 586 PHE B N   1 
ATOM   10301 C CA  . PHE B 1 566 ? 118.733 115.656 171.339 1.00 141.59 ? 586 PHE B CA  1 
ATOM   10302 C C   . PHE B 1 566 ? 117.335 116.199 171.617 1.00 139.51 ? 586 PHE B C   1 
ATOM   10303 O O   . PHE B 1 566 ? 116.981 116.413 172.774 1.00 140.39 ? 586 PHE B O   1 
ATOM   10304 C CB  . PHE B 1 566 ? 119.730 116.763 170.992 1.00 145.57 ? 586 PHE B CB  1 
ATOM   10305 C CG  . PHE B 1 566 ? 121.135 116.463 171.447 1.00 154.77 ? 586 PHE B CG  1 
ATOM   10306 C CD1 . PHE B 1 566 ? 121.488 116.582 172.783 1.00 158.80 ? 586 PHE B CD1 1 
ATOM   10307 C CD2 . PHE B 1 566 ? 122.091 116.011 170.551 1.00 160.43 ? 586 PHE B CD2 1 
ATOM   10308 C CE1 . PHE B 1 566 ? 122.777 116.293 173.206 1.00 161.86 ? 586 PHE B CE1 1 
ATOM   10309 C CE2 . PHE B 1 566 ? 123.380 115.723 170.974 1.00 161.47 ? 586 PHE B CE2 1 
ATOM   10310 C CZ  . PHE B 1 566 ? 123.721 115.862 172.301 1.00 162.35 ? 586 PHE B CZ  1 
ATOM   10311 N N   . ALA B 1 567 ? 116.545 116.413 170.559 1.00 138.74 ? 587 ALA B N   1 
ATOM   10312 C CA  . ALA B 1 567 ? 115.191 116.923 170.708 1.00 139.92 ? 587 ALA B CA  1 
ATOM   10313 C C   . ALA B 1 567 ? 114.331 115.938 171.507 1.00 144.70 ? 587 ALA B C   1 
ATOM   10314 O O   . ALA B 1 567 ? 113.552 116.348 172.374 1.00 142.86 ? 587 ALA B O   1 
ATOM   10315 C CB  . ALA B 1 567 ? 114.597 117.209 169.349 1.00 139.48 ? 587 ALA B CB  1 
ATOM   10316 N N   . CYS B 1 568 ? 114.485 114.640 171.211 1.00 149.83 ? 588 CYS B N   1 
ATOM   10317 C CA  . CYS B 1 568 ? 113.690 113.606 171.855 1.00 152.93 ? 588 CYS B CA  1 
ATOM   10318 C C   . CYS B 1 568 ? 114.065 113.479 173.333 1.00 148.75 ? 588 CYS B C   1 
ATOM   10319 O O   . CYS B 1 568 ? 113.186 113.333 174.184 1.00 149.35 ? 588 CYS B O   1 
ATOM   10320 C CB  . CYS B 1 568 ? 113.849 112.261 171.152 1.00 157.75 ? 588 CYS B CB  1 
ATOM   10321 S SG  . CYS B 1 568 ? 112.938 110.916 171.955 1.00 163.52 ? 588 CYS B SG  1 
ATOM   10322 N N   . LEU B 1 569 ? 115.368 113.543 173.643 1.00 143.08 ? 589 LEU B N   1 
ATOM   10323 C CA  . LEU B 1 569 ? 115.778 113.447 175.035 1.00 140.55 ? 589 LEU B CA  1 
ATOM   10324 C C   . LEU B 1 569 ? 115.303 114.692 175.782 1.00 135.85 ? 589 LEU B C   1 
ATOM   10325 O O   . LEU B 1 569 ? 114.893 114.581 176.933 1.00 135.85 ? 589 LEU B O   1 
ATOM   10326 C CB  . LEU B 1 569 ? 117.283 113.162 175.173 1.00 143.34 ? 589 LEU B CB  1 
ATOM   10327 C CG  . LEU B 1 569 ? 118.283 114.233 174.735 1.00 145.29 ? 589 LEU B CG  1 
ATOM   10328 C CD1 . LEU B 1 569 ? 118.605 115.211 175.859 1.00 146.13 ? 589 LEU B CD1 1 
ATOM   10329 C CD2 . LEU B 1 569 ? 119.572 113.587 174.239 1.00 144.88 ? 589 LEU B CD2 1 
ATOM   10330 N N   . GLY B 1 570 ? 115.291 115.850 175.110 1.00 132.75 ? 590 GLY B N   1 
ATOM   10331 C CA  . GLY B 1 570 ? 114.716 117.065 175.668 1.00 131.39 ? 590 GLY B CA  1 
ATOM   10332 C C   . GLY B 1 570 ? 113.240 116.894 176.016 1.00 131.42 ? 590 GLY B C   1 
ATOM   10333 O O   . GLY B 1 570 ? 112.813 117.299 177.097 1.00 134.14 ? 590 GLY B O   1 
ATOM   10334 N N   . LEU B 1 571 ? 112.478 116.277 175.100 1.00 130.65 ? 591 LEU B N   1 
ATOM   10335 C CA  . LEU B 1 571 ? 111.056 116.046 175.315 1.00 133.32 ? 591 LEU B CA  1 
ATOM   10336 C C   . LEU B 1 571 ? 110.847 115.162 176.541 1.00 137.16 ? 591 LEU B C   1 
ATOM   10337 O O   . LEU B 1 571 ? 109.967 115.428 177.360 1.00 136.17 ? 591 LEU B O   1 
ATOM   10338 C CB  . LEU B 1 571 ? 110.420 115.354 174.101 1.00 133.66 ? 591 LEU B CB  1 
ATOM   10339 C CG  . LEU B 1 571 ? 110.440 116.068 172.751 1.00 132.46 ? 591 LEU B CG  1 
ATOM   10340 C CD1 . LEU B 1 571 ? 109.248 115.629 171.910 1.00 133.72 ? 591 LEU B CD1 1 
ATOM   10341 C CD2 . LEU B 1 571 ? 110.458 117.577 172.897 1.00 131.28 ? 591 LEU B CD2 1 
ATOM   10342 N N   . LEU B 1 572 ? 111.641 114.087 176.639 1.00 143.66 ? 592 LEU B N   1 
ATOM   10343 C CA  . LEU B 1 572 ? 111.506 113.145 177.738 1.00 149.70 ? 592 LEU B CA  1 
ATOM   10344 C C   . LEU B 1 572 ? 111.784 113.859 179.060 1.00 148.58 ? 592 LEU B C   1 
ATOM   10345 O O   . LEU B 1 572 ? 111.055 113.669 180.033 1.00 147.84 ? 592 LEU B O   1 
ATOM   10346 C CB  . LEU B 1 572 ? 112.461 111.963 177.528 1.00 155.44 ? 592 LEU B CB  1 
ATOM   10347 C CG  . LEU B 1 572 ? 112.107 111.004 176.389 1.00 159.05 ? 592 LEU B CG  1 
ATOM   10348 C CD1 . LEU B 1 572 ? 113.086 109.840 176.345 1.00 160.19 ? 592 LEU B CD1 1 
ATOM   10349 C CD2 . LEU B 1 572 ? 110.679 110.487 176.513 1.00 160.12 ? 592 LEU B CD2 1 
ATOM   10350 N N   . ALA B 1 573 ? 112.833 114.689 179.080 1.00 150.95 ? 593 ALA B N   1 
ATOM   10351 C CA  . ALA B 1 573 ? 113.195 115.425 180.280 1.00 154.26 ? 593 ALA B CA  1 
ATOM   10352 C C   . ALA B 1 573 ? 112.060 116.366 180.673 1.00 155.58 ? 593 ALA B C   1 
ATOM   10353 O O   . ALA B 1 573 ? 111.725 116.463 181.851 1.00 157.65 ? 593 ALA B O   1 
ATOM   10354 C CB  . ALA B 1 573 ? 114.490 116.171 180.069 1.00 154.61 ? 593 ALA B CB  1 
ATOM   10355 N N   . THR B 1 574 ? 111.461 117.037 179.679 1.00 156.15 ? 594 THR B N   1 
ATOM   10356 C CA  . THR B 1 574 ? 110.399 117.994 179.941 1.00 157.97 ? 594 THR B CA  1 
ATOM   10357 C C   . THR B 1 574 ? 109.199 117.296 180.575 1.00 161.83 ? 594 THR B C   1 
ATOM   10358 O O   . THR B 1 574 ? 108.669 117.781 181.573 1.00 160.58 ? 594 THR B O   1 
ATOM   10359 C CB  . THR B 1 574 ? 109.972 118.739 178.671 1.00 158.65 ? 594 THR B CB  1 
ATOM   10360 O OG1 . THR B 1 574 ? 109.593 117.780 177.683 1.00 158.62 ? 594 THR B OG1 1 
ATOM   10361 C CG2 . THR B 1 574 ? 111.060 119.644 178.137 1.00 157.65 ? 594 THR B CG2 1 
ATOM   10362 N N   . LEU B 1 575 ? 108.779 116.163 179.996 1.00 168.68 ? 595 LEU B N   1 
ATOM   10363 C CA  . LEU B 1 575 ? 107.591 115.477 180.483 1.00 173.98 ? 595 LEU B CA  1 
ATOM   10364 C C   . LEU B 1 575 ? 107.855 114.894 181.874 1.00 172.97 ? 595 LEU B C   1 
ATOM   10365 O O   . LEU B 1 575 ? 106.971 114.931 182.731 1.00 170.82 ? 595 LEU B O   1 
ATOM   10366 C CB  . LEU B 1 575 ? 107.106 114.423 179.474 1.00 176.95 ? 595 LEU B CB  1 
ATOM   10367 C CG  . LEU B 1 575 ? 108.033 113.248 179.153 1.00 178.40 ? 595 LEU B CG  1 
ATOM   10368 C CD1 . LEU B 1 575 ? 107.769 112.058 180.068 1.00 179.05 ? 595 LEU B CD1 1 
ATOM   10369 C CD2 . LEU B 1 575 ? 107.880 112.824 177.698 1.00 178.32 ? 595 LEU B CD2 1 
ATOM   10370 N N   . PHE B 1 576 ? 109.078 114.397 182.107 1.00 174.76 ? 596 PHE B N   1 
ATOM   10371 C CA  . PHE B 1 576 ? 109.444 113.870 183.412 1.00 176.93 ? 596 PHE B CA  1 
ATOM   10372 C C   . PHE B 1 576 ? 109.359 114.978 184.463 1.00 171.18 ? 596 PHE B C   1 
ATOM   10373 O O   . PHE B 1 576 ? 108.810 114.772 185.545 1.00 170.27 ? 596 PHE B O   1 
ATOM   10374 C CB  . PHE B 1 576 ? 110.843 113.249 183.380 1.00 182.46 ? 596 PHE B CB  1 
ATOM   10375 C CG  . PHE B 1 576 ? 111.223 112.565 184.668 1.00 188.50 ? 596 PHE B CG  1 
ATOM   10376 C CD1 . PHE B 1 576 ? 110.596 111.389 185.050 1.00 192.80 ? 596 PHE B CD1 1 
ATOM   10377 C CD2 . PHE B 1 576 ? 112.194 113.097 185.504 1.00 190.08 ? 596 PHE B CD2 1 
ATOM   10378 C CE1 . PHE B 1 576 ? 110.938 110.754 186.236 1.00 194.43 ? 596 PHE B CE1 1 
ATOM   10379 C CE2 . PHE B 1 576 ? 112.533 112.463 186.691 1.00 192.07 ? 596 PHE B CE2 1 
ATOM   10380 C CZ  . PHE B 1 576 ? 111.905 111.292 187.054 1.00 193.63 ? 596 PHE B CZ  1 
ATOM   10381 N N   . VAL B 1 577 ? 109.906 116.155 184.128 1.00 168.16 ? 597 VAL B N   1 
ATOM   10382 C CA  . VAL B 1 577 ? 109.942 117.285 185.043 1.00 167.76 ? 597 VAL B CA  1 
ATOM   10383 C C   . VAL B 1 577 ? 108.518 117.739 185.351 1.00 171.09 ? 597 VAL B C   1 
ATOM   10384 O O   . VAL B 1 577 ? 108.211 118.040 186.501 1.00 172.06 ? 597 VAL B O   1 
ATOM   10385 C CB  . VAL B 1 577 ? 110.810 118.435 184.492 1.00 164.37 ? 597 VAL B CB  1 
ATOM   10386 C CG1 . VAL B 1 577 ? 110.471 119.782 185.116 1.00 162.72 ? 597 VAL B CG1 1 
ATOM   10387 C CG2 . VAL B 1 577 ? 112.292 118.132 184.657 1.00 161.85 ? 597 VAL B CG2 1 
ATOM   10388 N N   . THR B 1 578 ? 107.654 117.787 184.329 1.00 176.06 ? 598 THR B N   1 
ATOM   10389 C CA  . THR B 1 578 ? 106.298 118.275 184.522 1.00 181.58 ? 598 THR B CA  1 
ATOM   10390 C C   . THR B 1 578 ? 105.519 117.287 185.388 1.00 185.10 ? 598 THR B C   1 
ATOM   10391 O O   . THR B 1 578 ? 104.668 117.705 186.166 1.00 182.46 ? 598 THR B O   1 
ATOM   10392 C CB  . THR B 1 578 ? 105.609 118.590 183.187 1.00 182.80 ? 598 THR B CB  1 
ATOM   10393 O OG1 . THR B 1 578 ? 104.556 119.517 183.456 1.00 180.17 ? 598 THR B OG1 1 
ATOM   10394 C CG2 . THR B 1 578 ? 105.065 117.373 182.476 1.00 185.51 ? 598 THR B CG2 1 
ATOM   10395 N N   . VAL B 1 579 ? 105.804 115.984 185.253 1.00 187.84 ? 599 VAL B N   1 
ATOM   10396 C CA  . VAL B 1 579 ? 105.224 114.992 186.147 1.00 189.65 ? 599 VAL B CA  1 
ATOM   10397 C C   . VAL B 1 579 ? 105.620 115.337 187.583 1.00 189.30 ? 599 VAL B C   1 
ATOM   10398 O O   . VAL B 1 579 ? 104.757 115.555 188.433 1.00 189.81 ? 599 VAL B O   1 
ATOM   10399 C CB  . VAL B 1 579 ? 105.640 113.554 185.775 1.00 191.05 ? 599 VAL B CB  1 
ATOM   10400 C CG1 . VAL B 1 579 ? 105.374 112.576 186.914 1.00 191.22 ? 599 VAL B CG1 1 
ATOM   10401 C CG2 . VAL B 1 579 ? 104.963 113.083 184.496 1.00 190.88 ? 599 VAL B CG2 1 
ATOM   10402 N N   . VAL B 1 580 ? 106.934 115.419 187.826 1.00 188.68 ? 600 VAL B N   1 
ATOM   10403 C CA  . VAL B 1 580 ? 107.480 115.649 189.157 1.00 189.39 ? 600 VAL B CA  1 
ATOM   10404 C C   . VAL B 1 580 ? 106.814 116.875 189.782 1.00 189.72 ? 600 VAL B C   1 
ATOM   10405 O O   . VAL B 1 580 ? 106.432 116.842 190.953 1.00 189.87 ? 600 VAL B O   1 
ATOM   10406 C CB  . VAL B 1 580 ? 109.015 115.820 189.123 1.00 189.23 ? 600 VAL B CB  1 
ATOM   10407 C CG1 . VAL B 1 580 ? 109.552 116.366 190.438 1.00 189.44 ? 600 VAL B CG1 1 
ATOM   10408 C CG2 . VAL B 1 580 ? 109.741 114.535 188.747 1.00 188.51 ? 600 VAL B CG2 1 
ATOM   10409 N N   . PHE B 1 581 ? 106.662 117.940 188.982 1.00 189.92 ? 601 PHE B N   1 
ATOM   10410 C CA  . PHE B 1 581 ? 106.209 119.228 189.483 1.00 191.31 ? 601 PHE B CA  1 
ATOM   10411 C C   . PHE B 1 581 ? 104.794 119.118 190.046 1.00 194.67 ? 601 PHE B C   1 
ATOM   10412 O O   . PHE B 1 581 ? 104.505 119.712 191.081 1.00 194.42 ? 601 PHE B O   1 
ATOM   10413 C CB  . PHE B 1 581 ? 106.273 120.289 188.380 1.00 190.52 ? 601 PHE B CB  1 
ATOM   10414 C CG  . PHE B 1 581 ? 106.388 121.711 188.867 1.00 190.54 ? 601 PHE B CG  1 
ATOM   10415 C CD1 . PHE B 1 581 ? 105.318 122.352 189.475 1.00 192.07 ? 601 PHE B CD1 1 
ATOM   10416 C CD2 . PHE B 1 581 ? 107.579 122.407 188.723 1.00 190.22 ? 601 PHE B CD2 1 
ATOM   10417 C CE1 . PHE B 1 581 ? 105.437 123.660 189.921 1.00 193.72 ? 601 PHE B CE1 1 
ATOM   10418 C CE2 . PHE B 1 581 ? 107.695 123.715 189.167 1.00 190.93 ? 601 PHE B CE2 1 
ATOM   10419 C CZ  . PHE B 1 581 ? 106.625 124.337 189.769 1.00 192.82 ? 601 PHE B CZ  1 
ATOM   10420 N N   . ILE B 1 582 ? 103.916 118.365 189.365 1.00 198.21 ? 602 ILE B N   1 
ATOM   10421 C CA  . ILE B 1 582 ? 102.533 118.232 189.804 1.00 201.75 ? 602 ILE B CA  1 
ATOM   10422 C C   . ILE B 1 582 ? 102.450 117.260 190.985 1.00 201.29 ? 602 ILE B C   1 
ATOM   10423 O O   . ILE B 1 582 ? 101.576 117.408 191.834 1.00 198.29 ? 602 ILE B O   1 
ATOM   10424 C CB  . ILE B 1 582 ? 101.596 117.822 188.645 1.00 204.78 ? 602 ILE B CB  1 
ATOM   10425 C CG1 . ILE B 1 582 ? 101.758 116.347 188.263 1.00 207.21 ? 602 ILE B CG1 1 
ATOM   10426 C CG2 . ILE B 1 582 ? 101.784 118.738 187.441 1.00 203.54 ? 602 ILE B CG2 1 
ATOM   10427 C CD1 . ILE B 1 582 ? 100.755 115.855 187.243 1.00 207.89 ? 602 ILE B CD1 1 
ATOM   10428 N N   . ILE B 1 583 ? 103.370 116.289 191.052 1.00 201.37 ? 603 ILE B N   1 
ATOM   10429 C CA  . ILE B 1 583 ? 103.393 115.326 192.145 1.00 201.01 ? 603 ILE B CA  1 
ATOM   10430 C C   . ILE B 1 583 ? 103.395 116.089 193.471 1.00 202.20 ? 603 ILE B C   1 
ATOM   10431 O O   . ILE B 1 583 ? 102.653 115.751 194.395 1.00 200.17 ? 603 ILE B O   1 
ATOM   10432 C CB  . ILE B 1 583 ? 104.598 114.367 192.026 1.00 199.98 ? 603 ILE B CB  1 
ATOM   10433 C CG1 . ILE B 1 583 ? 104.494 113.464 190.791 1.00 199.14 ? 603 ILE B CG1 1 
ATOM   10434 C CG2 . ILE B 1 583 ? 104.762 113.550 193.305 1.00 199.91 ? 603 ILE B CG2 1 
ATOM   10435 C CD1 . ILE B 1 583 ? 105.652 112.502 190.598 1.00 198.83 ? 603 ILE B CD1 1 
ATOM   10436 N N   . TYR B 1 584 ? 104.252 117.115 193.544 1.00 204.01 ? 604 TYR B N   1 
ATOM   10437 C CA  . TYR B 1 584 ? 104.282 118.037 194.669 1.00 205.28 ? 604 TYR B CA  1 
ATOM   10438 C C   . TYR B 1 584 ? 104.038 119.447 194.142 1.00 199.11 ? 604 TYR B C   1 
ATOM   10439 O O   . TYR B 1 584 ? 104.985 120.175 193.863 1.00 197.44 ? 604 TYR B O   1 
ATOM   10440 C CB  . TYR B 1 584 ? 105.612 117.905 195.422 1.00 212.41 ? 604 TYR B CB  1 
ATOM   10441 C CG  . TYR B 1 584 ? 105.863 116.514 195.953 1.00 221.94 ? 604 TYR B CG  1 
ATOM   10442 C CD1 . TYR B 1 584 ? 104.975 115.918 196.838 1.00 226.97 ? 604 TYR B CD1 1 
ATOM   10443 C CD2 . TYR B 1 584 ? 106.954 115.766 195.536 1.00 225.55 ? 604 TYR B CD2 1 
ATOM   10444 C CE1 . TYR B 1 584 ? 105.179 114.634 197.319 1.00 229.63 ? 604 TYR B CE1 1 
ATOM   10445 C CE2 . TYR B 1 584 ? 107.172 114.480 196.007 1.00 228.07 ? 604 TYR B CE2 1 
ATOM   10446 C CZ  . TYR B 1 584 ? 106.283 113.911 196.902 1.00 229.35 ? 604 TYR B CZ  1 
ATOM   10447 O OH  . TYR B 1 584 ? 106.495 112.638 197.374 1.00 226.41 ? 604 TYR B OH  1 
ATOM   10448 N N   . ARG B 1 585 ? 102.755 119.808 194.018 1.00 198.00 ? 605 ARG B N   1 
ATOM   10449 C CA  . ARG B 1 585 ? 102.320 120.979 193.270 1.00 200.36 ? 605 ARG B CA  1 
ATOM   10450 C C   . ARG B 1 585 ? 102.215 122.211 194.168 1.00 202.82 ? 605 ARG B C   1 
ATOM   10451 O O   . ARG B 1 585 ? 102.597 123.300 193.748 1.00 200.04 ? 605 ARG B O   1 
ATOM   10452 C CB  . ARG B 1 585 ? 100.971 120.684 192.603 1.00 201.96 ? 605 ARG B CB  1 
ATOM   10453 C CG  . ARG B 1 585 ? 100.221 121.917 192.114 1.00 204.97 ? 605 ARG B CG  1 
ATOM   10454 C CD  . ARG B 1 585 ? 98.860  121.558 191.545 1.00 207.24 ? 605 ARG B CD  1 
ATOM   10455 N NE  . ARG B 1 585 ? 97.955  122.697 191.439 1.00 208.51 ? 605 ARG B NE  1 
ATOM   10456 C CZ  . ARG B 1 585 ? 98.082  123.706 190.580 1.00 210.15 ? 605 ARG B CZ  1 
ATOM   10457 N NH1 . ARG B 1 585 ? 99.075  123.729 189.708 1.00 210.71 ? 605 ARG B NH1 1 
ATOM   10458 N NH2 . ARG B 1 585 ? 97.202  124.694 190.592 1.00 208.82 ? 605 ARG B NH2 1 
ATOM   10459 N N   . ASP B 1 586 ? 101.682 122.037 195.387 1.00 206.47 ? 606 ASP B N   1 
ATOM   10460 C CA  . ASP B 1 586 ? 101.367 123.153 196.269 1.00 209.50 ? 606 ASP B CA  1 
ATOM   10461 C C   . ASP B 1 586 ? 102.435 123.298 197.352 1.00 208.98 ? 606 ASP B C   1 
ATOM   10462 O O   . ASP B 1 586 ? 102.739 124.409 197.785 1.00 207.87 ? 606 ASP B O   1 
ATOM   10463 C CB  . ASP B 1 586 ? 99.983  122.988 196.906 1.00 211.89 ? 606 ASP B CB  1 
ATOM   10464 C CG  . ASP B 1 586 ? 99.612  124.106 197.866 1.00 213.70 ? 606 ASP B CG  1 
ATOM   10465 O OD1 . ASP B 1 586 ? 99.574  125.276 197.423 1.00 214.86 ? 606 ASP B OD1 1 
ATOM   10466 O OD2 . ASP B 1 586 ? 99.374  123.801 199.051 1.00 213.23 ? 606 ASP B OD2 1 
ATOM   10467 N N   . THR B 1 587 ? 102.978 122.163 197.813 1.00 209.29 ? 607 THR B N   1 
ATOM   10468 C CA  . THR B 1 587 ? 104.010 122.119 198.844 1.00 208.72 ? 607 THR B CA  1 
ATOM   10469 C C   . THR B 1 587 ? 104.872 123.381 198.823 1.00 210.82 ? 607 THR B C   1 
ATOM   10470 O O   . THR B 1 587 ? 105.371 123.749 197.764 1.00 211.53 ? 607 THR B O   1 
ATOM   10471 C CB  . THR B 1 587 ? 104.942 120.914 198.647 1.00 205.39 ? 607 THR B CB  1 
ATOM   10472 O OG1 . THR B 1 587 ? 105.551 121.047 197.359 1.00 202.28 ? 607 THR B OG1 1 
ATOM   10473 C CG2 . THR B 1 587 ? 104.236 119.579 198.750 1.00 204.13 ? 607 THR B CG2 1 
ATOM   10474 N N   . PRO B 1 588 ? 105.110 124.069 199.969 1.00 212.17 ? 608 PRO B N   1 
ATOM   10475 C CA  . PRO B 1 588 ? 105.909 125.300 199.975 1.00 211.62 ? 608 PRO B CA  1 
ATOM   10476 C C   . PRO B 1 588 ? 107.297 125.160 199.346 1.00 209.84 ? 608 PRO B C   1 
ATOM   10477 O O   . PRO B 1 588 ? 107.843 126.128 198.816 1.00 208.54 ? 608 PRO B O   1 
ATOM   10478 C CB  . PRO B 1 588 ? 106.050 125.645 201.466 1.00 212.42 ? 608 PRO B CB  1 
ATOM   10479 C CG  . PRO B 1 588 ? 104.865 124.968 202.121 1.00 212.86 ? 608 PRO B CG  1 
ATOM   10480 C CD  . PRO B 1 588 ? 104.613 123.715 201.307 1.00 212.19 ? 608 PRO B CD  1 
ATOM   10481 N N   . VAL B 1 589 ? 107.842 123.936 199.399 1.00 208.57 ? 609 VAL B N   1 
ATOM   10482 C CA  . VAL B 1 589 ? 109.158 123.630 198.859 1.00 207.08 ? 609 VAL B CA  1 
ATOM   10483 C C   . VAL B 1 589 ? 109.217 124.006 197.379 1.00 202.30 ? 609 VAL B C   1 
ATOM   10484 O O   . VAL B 1 589 ? 110.214 124.564 196.934 1.00 198.69 ? 609 VAL B O   1 
ATOM   10485 C CB  . VAL B 1 589 ? 109.550 122.155 199.094 1.00 207.80 ? 609 VAL B CB  1 
ATOM   10486 C CG1 . VAL B 1 589 ? 109.754 121.858 200.573 1.00 206.00 ? 609 VAL B CG1 1 
ATOM   10487 C CG2 . VAL B 1 589 ? 108.562 121.169 198.487 1.00 207.49 ? 609 VAL B CG2 1 
ATOM   10488 N N   . VAL B 1 590 ? 108.146 123.712 196.631 1.00 202.49 ? 610 VAL B N   1 
ATOM   10489 C CA  . VAL B 1 590 ? 108.022 124.126 195.242 1.00 203.67 ? 610 VAL B CA  1 
ATOM   10490 C C   . VAL B 1 590 ? 107.261 125.451 195.149 1.00 205.78 ? 610 VAL B C   1 
ATOM   10491 O O   . VAL B 1 590 ? 107.469 126.206 194.202 1.00 206.85 ? 610 VAL B O   1 
ATOM   10492 C CB  . VAL B 1 590 ? 107.340 123.035 194.396 1.00 202.62 ? 610 VAL B CB  1 
ATOM   10493 C CG1 . VAL B 1 590 ? 108.125 121.735 194.398 1.00 200.82 ? 610 VAL B CG1 1 
ATOM   10494 C CG2 . VAL B 1 590 ? 105.904 122.781 194.826 1.00 203.92 ? 610 VAL B CG2 1 
ATOM   10495 N N   . LYS B 1 591 ? 106.403 125.743 196.137 1.00 207.86 ? 611 LYS B N   1 
ATOM   10496 C CA  . LYS B 1 591 ? 105.697 127.014 196.201 1.00 210.08 ? 611 LYS B CA  1 
ATOM   10497 C C   . LYS B 1 591 ? 106.669 128.112 196.631 1.00 211.62 ? 611 LYS B C   1 
ATOM   10498 O O   . LYS B 1 591 ? 106.514 128.730 197.687 1.00 211.93 ? 611 LYS B O   1 
ATOM   10499 C CB  . LYS B 1 591 ? 104.500 126.911 197.153 1.00 211.38 ? 611 LYS B CB  1 
ATOM   10500 C CG  . LYS B 1 591 ? 103.409 127.957 196.955 1.00 214.17 ? 611 LYS B CG  1 
ATOM   10501 C CD  . LYS B 1 591 ? 102.172 127.710 197.793 1.00 216.38 ? 611 LYS B CD  1 
ATOM   10502 C CE  . LYS B 1 591 ? 101.017 128.621 197.435 1.00 218.09 ? 611 LYS B CE  1 
ATOM   10503 N NZ  . LYS B 1 591 ? 99.798  128.292 198.212 1.00 218.47 ? 611 LYS B NZ  1 
ATOM   10504 N N   . SER B 1 592 ? 107.687 128.342 195.794 1.00 213.83 ? 612 SER B N   1 
ATOM   10505 C CA  . SER B 1 592 ? 108.642 129.417 196.012 1.00 216.43 ? 612 SER B CA  1 
ATOM   10506 C C   . SER B 1 592 ? 108.046 130.723 195.495 1.00 218.94 ? 612 SER B C   1 
ATOM   10507 O O   . SER B 1 592 ? 108.008 131.720 196.212 1.00 217.67 ? 612 SER B O   1 
ATOM   10508 C CB  . SER B 1 592 ? 109.968 129.111 195.360 1.00 215.81 ? 612 SER B CB  1 
ATOM   10509 O OG  . SER B 1 592 ? 109.794 128.799 193.987 1.00 215.16 ? 612 SER B OG  1 
ATOM   10510 N N   . SER B 1 593 ? 107.619 130.703 194.226 1.00 219.56 ? 613 SER B N   1 
ATOM   10511 C CA  . SER B 1 593 ? 106.988 131.834 193.570 1.00 219.61 ? 613 SER B CA  1 
ATOM   10512 C C   . SER B 1 593 ? 105.691 131.344 192.933 1.00 220.15 ? 613 SER B C   1 
ATOM   10513 O O   . SER B 1 593 ? 105.283 130.206 193.167 1.00 217.80 ? 613 SER B O   1 
ATOM   10514 C CB  . SER B 1 593 ? 107.918 132.459 192.551 1.00 219.12 ? 613 SER B CB  1 
ATOM   10515 O OG  . SER B 1 593 ? 109.124 132.898 193.161 1.00 218.04 ? 613 SER B OG  1 
ATOM   10516 N N   . SER B 1 594 ? 105.047 132.210 192.142 1.00 221.25 ? 614 SER B N   1 
ATOM   10517 C CA  . SER B 1 594 ? 103.844 131.837 191.416 1.00 221.06 ? 614 SER B CA  1 
ATOM   10518 C C   . SER B 1 594 ? 104.133 130.622 190.536 1.00 218.84 ? 614 SER B C   1 
ATOM   10519 O O   . SER B 1 594 ? 104.929 130.702 189.603 1.00 215.93 ? 614 SER B O   1 
ATOM   10520 C CB  . SER B 1 594 ? 103.316 132.988 190.602 1.00 222.15 ? 614 SER B CB  1 
ATOM   10521 O OG  . SER B 1 594 ? 102.086 132.645 189.984 1.00 222.34 ? 614 SER B OG  1 
ATOM   10522 N N   . ARG B 1 595 ? 103.453 129.510 190.836 1.00 217.58 ? 615 ARG B N   1 
ATOM   10523 C CA  . ARG B 1 595 ? 103.702 128.237 190.182 1.00 215.51 ? 615 ARG B CA  1 
ATOM   10524 C C   . ARG B 1 595 ? 103.298 128.295 188.710 1.00 209.19 ? 615 ARG B C   1 
ATOM   10525 O O   . ARG B 1 595 ? 103.682 127.415 187.945 1.00 205.02 ? 615 ARG B O   1 
ATOM   10526 C CB  . ARG B 1 595 ? 102.946 127.128 190.920 1.00 220.14 ? 615 ARG B CB  1 
ATOM   10527 C CG  . ARG B 1 595 ? 103.387 126.957 192.368 1.00 223.94 ? 615 ARG B CG  1 
ATOM   10528 C CD  . ARG B 1 595 ? 102.222 126.982 193.341 1.00 226.83 ? 615 ARG B CD  1 
ATOM   10529 N NE  . ARG B 1 595 ? 101.420 128.197 193.233 1.00 228.79 ? 615 ARG B NE  1 
ATOM   10530 C CZ  . ARG B 1 595 ? 101.810 129.423 193.582 1.00 230.20 ? 615 ARG B CZ  1 
ATOM   10531 N NH1 . ARG B 1 595 ? 103.008 129.637 194.098 1.00 229.88 ? 615 ARG B NH1 1 
ATOM   10532 N NH2 . ARG B 1 595 ? 100.983 130.443 193.415 1.00 228.70 ? 615 ARG B NH2 1 
ATOM   10533 N N   . GLU B 1 596 ? 102.513 129.310 188.319 1.00 204.98 ? 616 GLU B N   1 
ATOM   10534 C CA  . GLU B 1 596 ? 102.113 129.471 186.930 1.00 201.97 ? 616 GLU B CA  1 
ATOM   10535 C C   . GLU B 1 596 ? 103.330 129.799 186.068 1.00 193.81 ? 616 GLU B C   1 
ATOM   10536 O O   . GLU B 1 596 ? 103.425 129.316 184.946 1.00 191.28 ? 616 GLU B O   1 
ATOM   10537 C CB  . GLU B 1 596 ? 101.026 130.540 186.784 1.00 205.04 ? 616 GLU B CB  1 
ATOM   10538 C CG  . GLU B 1 596 ? 100.320 130.525 185.434 1.00 207.74 ? 616 GLU B CG  1 
ATOM   10539 C CD  . GLU B 1 596 ? 99.340  129.387 185.189 1.00 209.77 ? 616 GLU B CD  1 
ATOM   10540 O OE1 . GLU B 1 596 ? 99.129  128.569 186.107 1.00 209.92 ? 616 GLU B OE1 1 
ATOM   10541 O OE2 . GLU B 1 596 ? 98.778  129.330 184.077 1.00 208.90 ? 616 GLU B OE2 1 
ATOM   10542 N N   . LEU B 1 597 ? 104.258 130.615 186.585 1.00 185.44 ? 617 LEU B N   1 
ATOM   10543 C CA  . LEU B 1 597 ? 105.481 130.941 185.863 1.00 177.68 ? 617 LEU B CA  1 
ATOM   10544 C C   . LEU B 1 597 ? 106.274 129.671 185.558 1.00 178.77 ? 617 LEU B C   1 
ATOM   10545 O O   . LEU B 1 597 ? 106.794 129.517 184.459 1.00 177.89 ? 617 LEU B O   1 
ATOM   10546 C CB  . LEU B 1 597 ? 106.328 131.912 186.693 1.00 170.49 ? 617 LEU B CB  1 
ATOM   10547 C CG  . LEU B 1 597 ? 105.783 133.333 186.848 1.00 165.63 ? 617 LEU B CG  1 
ATOM   10548 C CD1 . LEU B 1 597 ? 106.869 134.263 187.366 1.00 165.09 ? 617 LEU B CD1 1 
ATOM   10549 C CD2 . LEU B 1 597 ? 105.215 133.866 185.541 1.00 162.08 ? 617 LEU B CD2 1 
ATOM   10550 N N   . CYS B 1 598 ? 106.357 128.764 186.538 1.00 178.72 ? 618 CYS B N   1 
ATOM   10551 C CA  . CYS B 1 598 ? 107.075 127.510 186.376 1.00 178.98 ? 618 CYS B CA  1 
ATOM   10552 C C   . CYS B 1 598 ? 106.277 126.493 185.554 1.00 177.40 ? 618 CYS B C   1 
ATOM   10553 O O   . CYS B 1 598 ? 106.659 125.330 185.492 1.00 176.58 ? 618 CYS B O   1 
ATOM   10554 C CB  . CYS B 1 598 ? 107.424 126.908 187.733 1.00 182.14 ? 618 CYS B CB  1 
ATOM   10555 S SG  . CYS B 1 598 ? 108.503 127.959 188.741 1.00 187.70 ? 618 CYS B SG  1 
ATOM   10556 N N   . TYR B 1 599 ? 105.140 126.907 184.978 1.00 176.80 ? 619 TYR B N   1 
ATOM   10557 C CA  . TYR B 1 599 ? 104.443 126.159 183.941 1.00 178.13 ? 619 TYR B CA  1 
ATOM   10558 C C   . TYR B 1 599 ? 104.664 126.829 182.584 1.00 169.10 ? 619 TYR B C   1 
ATOM   10559 O O   . TYR B 1 599 ? 104.778 126.155 181.563 1.00 166.39 ? 619 TYR B O   1 
ATOM   10560 C CB  . TYR B 1 599 ? 102.944 126.083 184.256 1.00 186.87 ? 619 TYR B CB  1 
ATOM   10561 C CG  . TYR B 1 599 ? 102.071 125.705 183.085 1.00 194.65 ? 619 TYR B CG  1 
ATOM   10562 C CD1 . TYR B 1 599 ? 102.177 124.458 182.492 1.00 194.84 ? 619 TYR B CD1 1 
ATOM   10563 C CD2 . TYR B 1 599 ? 101.152 126.599 182.553 1.00 197.44 ? 619 TYR B CD2 1 
ATOM   10564 C CE1 . TYR B 1 599 ? 101.383 124.100 181.413 1.00 194.10 ? 619 TYR B CE1 1 
ATOM   10565 C CE2 . TYR B 1 599 ? 100.352 126.258 181.474 1.00 195.80 ? 619 TYR B CE2 1 
ATOM   10566 C CZ  . TYR B 1 599 ? 100.468 125.004 180.901 1.00 194.30 ? 619 TYR B CZ  1 
ATOM   10567 O OH  . TYR B 1 599 ? 99.679  124.659 179.830 1.00 192.41 ? 619 TYR B OH  1 
ATOM   10568 N N   . ILE B 1 600 ? 104.735 128.164 182.586 1.00 162.43 ? 620 ILE B N   1 
ATOM   10569 C CA  . ILE B 1 600 ? 105.054 128.926 181.389 1.00 157.93 ? 620 ILE B CA  1 
ATOM   10570 C C   . ILE B 1 600 ? 106.437 128.507 180.884 1.00 151.75 ? 620 ILE B C   1 
ATOM   10571 O O   . ILE B 1 600 ? 106.621 128.309 179.687 1.00 148.37 ? 620 ILE B O   1 
ATOM   10572 C CB  . ILE B 1 600 ? 104.969 130.447 181.646 1.00 156.62 ? 620 ILE B CB  1 
ATOM   10573 C CG1 . ILE B 1 600 ? 103.632 130.873 182.263 1.00 157.17 ? 620 ILE B CG1 1 
ATOM   10574 C CG2 . ILE B 1 600 ? 105.255 131.226 180.367 1.00 155.10 ? 620 ILE B CG2 1 
ATOM   10575 C CD1 . ILE B 1 600 ? 102.410 130.417 181.495 1.00 159.68 ? 620 ILE B CD1 1 
ATOM   10576 N N   . ILE B 1 601 ? 107.405 128.354 181.795 1.00 146.68 ? 621 ILE B N   1 
ATOM   10577 C CA  . ILE B 1 601 ? 108.762 128.030 181.388 1.00 142.93 ? 621 ILE B CA  1 
ATOM   10578 C C   . ILE B 1 601 ? 108.797 126.613 180.820 1.00 138.05 ? 621 ILE B C   1 
ATOM   10579 O O   . ILE B 1 601 ? 109.474 126.375 179.825 1.00 137.74 ? 621 ILE B O   1 
ATOM   10580 C CB  . ILE B 1 601 ? 109.769 128.227 182.536 1.00 143.02 ? 621 ILE B CB  1 
ATOM   10581 C CG1 . ILE B 1 601 ? 109.692 129.646 183.104 1.00 143.30 ? 621 ILE B CG1 1 
ATOM   10582 C CG2 . ILE B 1 601 ? 111.173 127.902 182.057 1.00 142.24 ? 621 ILE B CG2 1 
ATOM   10583 C CD1 . ILE B 1 601 ? 110.614 129.909 184.276 1.00 143.93 ? 621 ILE B CD1 1 
ATOM   10584 N N   . LEU B 1 602 ? 108.073 125.674 181.441 1.00 134.51 ? 622 LEU B N   1 
ATOM   10585 C CA  . LEU B 1 602 ? 108.023 124.303 180.952 1.00 134.38 ? 622 LEU B CA  1 
ATOM   10586 C C   . LEU B 1 602 ? 107.446 124.274 179.536 1.00 129.62 ? 622 LEU B C   1 
ATOM   10587 O O   . LEU B 1 602 ? 107.979 123.594 178.667 1.00 126.04 ? 622 LEU B O   1 
ATOM   10588 C CB  . LEU B 1 602 ? 107.191 123.440 181.909 1.00 138.31 ? 622 LEU B CB  1 
ATOM   10589 C CG  . LEU B 1 602 ? 107.964 122.724 183.017 1.00 140.11 ? 622 LEU B CG  1 
ATOM   10590 C CD1 . LEU B 1 602 ? 108.702 123.703 183.914 1.00 139.63 ? 622 LEU B CD1 1 
ATOM   10591 C CD2 . LEU B 1 602 ? 107.024 121.857 183.840 1.00 141.02 ? 622 LEU B CD2 1 
ATOM   10592 N N   . ALA B 1 603 ? 106.353 125.012 179.315 1.00 128.45 ? 623 ALA B N   1 
ATOM   10593 C CA  . ALA B 1 603 ? 105.714 125.064 178.009 1.00 127.69 ? 623 ALA B CA  1 
ATOM   10594 C C   . ALA B 1 603 ? 106.676 125.657 176.983 1.00 120.57 ? 623 ALA B C   1 
ATOM   10595 O O   . ALA B 1 603 ? 106.739 125.191 175.848 1.00 118.53 ? 623 ALA B O   1 
ATOM   10596 C CB  . ALA B 1 603 ? 104.432 125.860 178.087 1.00 130.86 ? 623 ALA B CB  1 
ATOM   10597 N N   . GLY B 1 604 ? 107.414 126.695 177.393 1.00 115.36 ? 624 GLY B N   1 
ATOM   10598 C CA  . GLY B 1 604 ? 108.429 127.306 176.551 1.00 112.03 ? 624 GLY B CA  1 
ATOM   10599 C C   . GLY B 1 604 ? 109.482 126.293 176.110 1.00 108.65 ? 624 GLY B C   1 
ATOM   10600 O O   . GLY B 1 604 ? 109.813 126.217 174.932 1.00 109.49 ? 624 GLY B O   1 
ATOM   10601 N N   . ILE B 1 605 ? 109.982 125.495 177.058 1.00 103.21 ? 625 ILE B N   1 
ATOM   10602 C CA  . ILE B 1 605 ? 111.026 124.529 176.761 1.00 99.35  ? 625 ILE B CA  1 
ATOM   10603 C C   . ILE B 1 605 ? 110.473 123.469 175.810 1.00 100.51 ? 625 ILE B C   1 
ATOM   10604 O O   . ILE B 1 605 ? 111.153 123.076 174.863 1.00 100.34 ? 625 ILE B O   1 
ATOM   10605 C CB  . ILE B 1 605 ? 111.595 123.915 178.057 1.00 97.76  ? 625 ILE B CB  1 
ATOM   10606 C CG1 . ILE B 1 605 ? 112.222 124.986 178.953 1.00 97.91  ? 625 ILE B CG1 1 
ATOM   10607 C CG2 . ILE B 1 605 ? 112.577 122.794 177.740 1.00 97.24  ? 625 ILE B CG2 1 
ATOM   10608 C CD1 . ILE B 1 605 ? 112.507 124.515 180.359 1.00 98.90  ? 625 ILE B CD1 1 
ATOM   10609 N N   . CYS B 1 606 ? 109.234 123.024 176.059 1.00 102.35 ? 626 CYS B N   1 
ATOM   10610 C CA  . CYS B 1 606 ? 108.617 121.998 175.235 1.00 104.08 ? 626 CYS B CA  1 
ATOM   10611 C C   . CYS B 1 606 ? 108.523 122.489 173.792 1.00 102.81 ? 626 CYS B C   1 
ATOM   10612 O O   . CYS B 1 606 ? 108.996 121.813 172.880 1.00 102.81 ? 626 CYS B O   1 
ATOM   10613 C CB  . CYS B 1 606 ? 107.233 121.610 175.743 1.00 107.55 ? 626 CYS B CB  1 
ATOM   10614 S SG  . CYS B 1 606 ? 107.177 121.253 177.519 1.00 110.80 ? 626 CYS B SG  1 
ATOM   10615 N N   . LEU B 1 607 ? 107.942 123.678 173.584 1.00 101.20 ? 627 LEU B N   1 
ATOM   10616 C CA  . LEU B 1 607 ? 107.693 124.114 172.218 1.00 100.86 ? 627 LEU B CA  1 
ATOM   10617 C C   . LEU B 1 607 ? 109.006 124.553 171.565 1.00 96.81  ? 627 LEU B C   1 
ATOM   10618 O O   . LEU B 1 607 ? 109.133 124.455 170.349 1.00 96.93  ? 627 LEU B O   1 
ATOM   10619 C CB  . LEU B 1 607 ? 106.555 125.146 172.149 1.00 103.05 ? 627 LEU B CB  1 
ATOM   10620 C CG  . LEU B 1 607 ? 106.842 126.607 172.500 1.00 104.61 ? 627 LEU B CG  1 
ATOM   10621 C CD1 . LEU B 1 607 ? 107.258 127.410 171.275 1.00 104.27 ? 627 LEU B CD1 1 
ATOM   10622 C CD2 . LEU B 1 607 ? 105.619 127.249 173.134 1.00 106.77 ? 627 LEU B CD2 1 
ATOM   10623 N N   . GLY B 1 608 ? 110.001 124.944 172.370 1.00 92.16  ? 628 GLY B N   1 
ATOM   10624 C CA  . GLY B 1 608 ? 111.352 125.166 171.877 1.00 89.05  ? 628 GLY B CA  1 
ATOM   10625 C C   . GLY B 1 608 ? 111.936 123.902 171.254 1.00 85.86  ? 628 GLY B C   1 
ATOM   10626 O O   . GLY B 1 608 ? 112.532 123.953 170.184 1.00 87.38  ? 628 GLY B O   1 
ATOM   10627 N N   . TYR B 1 609 ? 111.753 122.763 171.924 1.00 83.06  ? 629 TYR B N   1 
ATOM   10628 C CA  . TYR B 1 609 ? 112.202 121.498 171.373 1.00 83.83  ? 629 TYR B CA  1 
ATOM   10629 C C   . TYR B 1 609 ? 111.356 121.112 170.161 1.00 86.05  ? 629 TYR B C   1 
ATOM   10630 O O   . TYR B 1 609 ? 111.889 120.605 169.180 1.00 86.16  ? 629 TYR B O   1 
ATOM   10631 C CB  . TYR B 1 609 ? 112.193 120.407 172.443 1.00 85.11  ? 629 TYR B CB  1 
ATOM   10632 C CG  . TYR B 1 609 ? 113.362 120.474 173.389 1.00 84.03  ? 629 TYR B CG  1 
ATOM   10633 C CD1 . TYR B 1 609 ? 114.658 120.464 172.905 1.00 82.88  ? 629 TYR B CD1 1 
ATOM   10634 C CD2 . TYR B 1 609 ? 113.178 120.543 174.761 1.00 84.39  ? 629 TYR B CD2 1 
ATOM   10635 C CE1 . TYR B 1 609 ? 115.744 120.536 173.757 1.00 83.14  ? 629 TYR B CE1 1 
ATOM   10636 C CE2 . TYR B 1 609 ? 114.257 120.595 175.630 1.00 84.58  ? 629 TYR B CE2 1 
ATOM   10637 C CZ  . TYR B 1 609 ? 115.545 120.598 175.124 1.00 84.24  ? 629 TYR B CZ  1 
ATOM   10638 O OH  . TYR B 1 609 ? 116.639 120.657 175.943 1.00 85.23  ? 629 TYR B OH  1 
ATOM   10639 N N   . LEU B 1 610 ? 110.045 121.370 170.215 1.00 88.87  ? 630 LEU B N   1 
ATOM   10640 C CA  . LEU B 1 610 ? 109.147 120.963 169.142 1.00 91.30  ? 630 LEU B CA  1 
ATOM   10641 C C   . LEU B 1 610 ? 109.483 121.700 167.844 1.00 91.01  ? 630 LEU B C   1 
ATOM   10642 O O   . LEU B 1 610 ? 109.228 121.183 166.766 1.00 90.60  ? 630 LEU B O   1 
ATOM   10643 C CB  . LEU B 1 610 ? 107.691 121.215 169.555 1.00 92.99  ? 630 LEU B CB  1 
ATOM   10644 C CG  . LEU B 1 610 ? 106.971 120.052 170.244 1.00 95.08  ? 630 LEU B CG  1 
ATOM   10645 C CD1 . LEU B 1 610 ? 106.721 118.907 169.273 1.00 97.07  ? 630 LEU B CD1 1 
ATOM   10646 C CD2 . LEU B 1 610 ? 107.745 119.551 171.454 1.00 94.61  ? 630 LEU B CD2 1 
ATOM   10647 N N   . CYS B 1 611 ? 110.032 122.914 167.946 1.00 90.06  ? 631 CYS B N   1 
ATOM   10648 C CA  . CYS B 1 611 ? 110.388 123.677 166.762 1.00 89.65  ? 631 CYS B CA  1 
ATOM   10649 C C   . CYS B 1 611 ? 111.514 122.998 165.980 1.00 88.27  ? 631 CYS B C   1 
ATOM   10650 O O   . CYS B 1 611 ? 111.666 123.270 164.792 1.00 89.70  ? 631 CYS B O   1 
ATOM   10651 C CB  . CYS B 1 611 ? 110.795 125.104 167.112 1.00 90.00  ? 631 CYS B CB  1 
ATOM   10652 S SG  . CYS B 1 611 ? 111.194 126.110 165.658 1.00 94.10  ? 631 CYS B SG  1 
ATOM   10653 N N   . THR B 1 612 ? 112.304 122.139 166.642 1.00 86.56  ? 632 THR B N   1 
ATOM   10654 C CA  . THR B 1 612 ? 113.376 121.422 165.967 1.00 86.57  ? 632 THR B CA  1 
ATOM   10655 C C   . THR B 1 612 ? 112.816 120.604 164.806 1.00 88.85  ? 632 THR B C   1 
ATOM   10656 O O   . THR B 1 612 ? 113.368 120.632 163.709 1.00 90.05  ? 632 THR B O   1 
ATOM   10657 C CB  . THR B 1 612 ? 114.163 120.515 166.926 1.00 85.20  ? 632 THR B CB  1 
ATOM   10658 O OG1 . THR B 1 612 ? 115.097 121.331 167.634 1.00 85.67  ? 632 THR B OG1 1 
ATOM   10659 C CG2 . THR B 1 612 ? 114.920 119.406 166.228 1.00 83.86  ? 632 THR B CG2 1 
ATOM   10660 N N   . PHE B 1 613 ? 111.723 119.879 165.069 1.00 90.67  ? 633 PHE B N   1 
ATOM   10661 C CA  . PHE B 1 613 ? 111.148 118.979 164.085 1.00 90.67  ? 633 PHE B CA  1 
ATOM   10662 C C   . PHE B 1 613 ? 110.605 119.772 162.901 1.00 89.40  ? 633 PHE B C   1 
ATOM   10663 O O   . PHE B 1 613 ? 110.773 119.356 161.758 1.00 89.82  ? 633 PHE B O   1 
ATOM   10664 C CB  . PHE B 1 613 ? 110.079 118.098 164.735 1.00 91.79  ? 633 PHE B CB  1 
ATOM   10665 C CG  . PHE B 1 613 ? 110.603 117.274 165.885 1.00 92.96  ? 633 PHE B CG  1 
ATOM   10666 C CD1 . PHE B 1 613 ? 111.628 116.359 165.689 1.00 93.35  ? 633 PHE B CD1 1 
ATOM   10667 C CD2 . PHE B 1 613 ? 110.114 117.449 167.171 1.00 93.23  ? 633 PHE B CD2 1 
ATOM   10668 C CE1 . PHE B 1 613 ? 112.132 115.623 166.749 1.00 94.41  ? 633 PHE B CE1 1 
ATOM   10669 C CE2 . PHE B 1 613 ? 110.623 116.713 168.228 1.00 94.72  ? 633 PHE B CE2 1 
ATOM   10670 C CZ  . PHE B 1 613 ? 111.622 115.792 168.014 1.00 95.83  ? 633 PHE B CZ  1 
ATOM   10671 N N   . CYS B 1 614 ? 109.961 120.910 163.179 1.00 89.70  ? 634 CYS B N   1 
ATOM   10672 C CA  . CYS B 1 614 ? 109.382 121.713 162.112 1.00 92.25  ? 634 CYS B CA  1 
ATOM   10673 C C   . CYS B 1 614 ? 110.466 122.513 161.386 1.00 92.16  ? 634 CYS B C   1 
ATOM   10674 O O   . CYS B 1 614 ? 110.195 123.102 160.338 1.00 92.88  ? 634 CYS B O   1 
ATOM   10675 C CB  . CYS B 1 614 ? 108.277 122.626 162.632 1.00 93.66  ? 634 CYS B CB  1 
ATOM   10676 S SG  . CYS B 1 614 ? 108.882 124.060 163.555 1.00 95.03  ? 634 CYS B SG  1 
ATOM   10677 N N   . LEU B 1 615 ? 111.683 122.552 161.946 1.00 92.77  ? 635 LEU B N   1 
ATOM   10678 C CA  . LEU B 1 615 ? 112.807 123.240 161.323 1.00 93.83  ? 635 LEU B CA  1 
ATOM   10679 C C   . LEU B 1 615 ? 113.682 122.260 160.542 1.00 94.38  ? 635 LEU B C   1 
ATOM   10680 O O   . LEU B 1 615 ? 114.508 122.701 159.748 1.00 94.35  ? 635 LEU B O   1 
ATOM   10681 C CB  . LEU B 1 615 ? 113.611 123.943 162.427 1.00 93.54  ? 635 LEU B CB  1 
ATOM   10682 C CG  . LEU B 1 615 ? 114.751 124.860 161.983 1.00 92.14  ? 635 LEU B CG  1 
ATOM   10683 C CD1 . LEU B 1 615 ? 114.247 126.030 161.152 1.00 92.88  ? 635 LEU B CD1 1 
ATOM   10684 C CD2 . LEU B 1 615 ? 115.499 125.391 163.191 1.00 91.31  ? 635 LEU B CD2 1 
ATOM   10685 N N   . ILE B 1 616 ? 113.529 120.946 160.775 1.00 96.79  ? 636 ILE B N   1 
ATOM   10686 C CA  . ILE B 1 616 ? 114.467 119.957 160.258 1.00 101.30 ? 636 ILE B CA  1 
ATOM   10687 C C   . ILE B 1 616 ? 113.794 119.060 159.216 1.00 105.55 ? 636 ILE B C   1 
ATOM   10688 O O   . ILE B 1 616 ? 114.394 118.079 158.782 1.00 106.96 ? 636 ILE B O   1 
ATOM   10689 C CB  . ILE B 1 616 ? 115.063 119.124 161.415 1.00 104.57 ? 636 ILE B CB  1 
ATOM   10690 C CG1 . ILE B 1 616 ? 116.383 118.443 161.032 1.00 106.45 ? 636 ILE B CG1 1 
ATOM   10691 C CG2 . ILE B 1 616 ? 114.038 118.127 161.940 1.00 106.39 ? 636 ILE B CG2 1 
ATOM   10692 C CD1 . ILE B 1 616 ? 117.093 117.790 162.190 1.00 108.40 ? 636 ILE B CD1 1 
ATOM   10693 N N   . ALA B 1 617 ? 112.566 119.394 158.798 1.00 111.57 ? 637 ALA B N   1 
ATOM   10694 C CA  . ALA B 1 617 ? 111.818 118.547 157.881 1.00 118.71 ? 637 ALA B CA  1 
ATOM   10695 C C   . ALA B 1 617 ? 111.862 119.135 156.473 1.00 124.50 ? 637 ALA B C   1 
ATOM   10696 O O   . ALA B 1 617 ? 112.500 120.161 156.243 1.00 125.34 ? 637 ALA B O   1 
ATOM   10697 C CB  . ALA B 1 617 ? 110.400 118.404 158.374 1.00 119.15 ? 637 ALA B CB  1 
ATOM   10698 N N   . LYS B 1 618 ? 111.170 118.469 155.540 1.00 128.87 ? 638 LYS B N   1 
ATOM   10699 C CA  . LYS B 1 618 ? 110.962 118.991 154.199 1.00 131.76 ? 638 LYS B CA  1 
ATOM   10700 C C   . LYS B 1 618 ? 110.370 120.395 154.310 1.00 130.05 ? 638 LYS B C   1 
ATOM   10701 O O   . LYS B 1 618 ? 109.335 120.580 154.945 1.00 130.28 ? 638 LYS B O   1 
ATOM   10702 C CB  . LYS B 1 618 ? 110.025 118.074 153.403 1.00 137.55 ? 638 LYS B CB  1 
ATOM   10703 C CG  . LYS B 1 618 ? 110.437 117.827 151.960 1.00 142.31 ? 638 LYS B CG  1 
ATOM   10704 C CD  . LYS B 1 618 ? 111.654 116.941 151.846 1.00 145.05 ? 638 LYS B CD  1 
ATOM   10705 C CE  . LYS B 1 618 ? 112.124 116.748 150.419 1.00 146.23 ? 638 LYS B CE  1 
ATOM   10706 N NZ  . LYS B 1 618 ? 112.697 117.992 149.849 1.00 146.07 ? 638 LYS B NZ  1 
ATOM   10707 N N   . PRO B 1 619 ? 111.028 121.439 153.757 1.00 129.99 ? 639 PRO B N   1 
ATOM   10708 C CA  . PRO B 1 619 ? 110.460 122.788 153.750 1.00 131.20 ? 639 PRO B CA  1 
ATOM   10709 C C   . PRO B 1 619 ? 109.128 122.856 153.006 1.00 133.41 ? 639 PRO B C   1 
ATOM   10710 O O   . PRO B 1 619 ? 109.079 122.697 151.789 1.00 131.98 ? 639 PRO B O   1 
ATOM   10711 C CB  . PRO B 1 619 ? 111.531 123.636 153.046 1.00 131.72 ? 639 PRO B CB  1 
ATOM   10712 C CG  . PRO B 1 619 ? 112.807 122.845 153.233 1.00 132.86 ? 639 PRO B CG  1 
ATOM   10713 C CD  . PRO B 1 619 ? 112.377 121.395 153.176 1.00 130.78 ? 639 PRO B CD  1 
ATOM   10714 N N   . LYS B 1 620 ? 108.049 123.070 153.769 1.00 138.35 ? 640 LYS B N   1 
ATOM   10715 C CA  . LYS B 1 620 ? 106.717 123.271 153.221 1.00 141.97 ? 640 LYS B CA  1 
ATOM   10716 C C   . LYS B 1 620 ? 106.162 124.581 153.770 1.00 143.74 ? 640 LYS B C   1 
ATOM   10717 O O   . LYS B 1 620 ? 106.749 125.181 154.669 1.00 143.41 ? 640 LYS B O   1 
ATOM   10718 C CB  . LYS B 1 620 ? 105.794 122.104 153.583 1.00 143.19 ? 640 LYS B CB  1 
ATOM   10719 C CG  . LYS B 1 620 ? 106.290 120.736 153.137 1.00 144.33 ? 640 LYS B CG  1 
ATOM   10720 C CD  . LYS B 1 620 ? 105.478 119.590 153.682 1.00 145.73 ? 640 LYS B CD  1 
ATOM   10721 C CE  . LYS B 1 620 ? 106.293 118.324 153.841 1.00 146.88 ? 640 LYS B CE  1 
ATOM   10722 N NZ  . LYS B 1 620 ? 107.235 118.428 154.982 1.00 146.66 ? 640 LYS B NZ  1 
ATOM   10723 N N   . GLN B 1 621 ? 105.021 125.014 153.221 1.00 148.28 ? 641 GLN B N   1 
ATOM   10724 C CA  . GLN B 1 621 ? 104.408 126.266 153.629 1.00 152.60 ? 641 GLN B CA  1 
ATOM   10725 C C   . GLN B 1 621 ? 104.030 126.193 155.105 1.00 157.35 ? 641 GLN B C   1 
ATOM   10726 O O   . GLN B 1 621 ? 104.331 127.112 155.857 1.00 156.35 ? 641 GLN B O   1 
ATOM   10727 C CB  . GLN B 1 621 ? 103.184 126.591 152.767 1.00 152.57 ? 641 GLN B CB  1 
ATOM   10728 C CG  . GLN B 1 621 ? 102.514 127.922 153.103 1.00 152.69 ? 641 GLN B CG  1 
ATOM   10729 C CD  . GLN B 1 621 ? 103.466 129.096 153.091 1.00 153.55 ? 641 GLN B CD  1 
ATOM   10730 O OE1 . GLN B 1 621 ? 104.350 129.208 153.936 1.00 153.82 ? 641 GLN B OE1 1 
ATOM   10731 N NE2 . GLN B 1 621 ? 103.293 129.991 152.133 1.00 154.02 ? 641 GLN B NE2 1 
ATOM   10732 N N   . ILE B 1 622 ? 103.360 125.107 155.501 1.00 161.41 ? 642 ILE B N   1 
ATOM   10733 C CA  . ILE B 1 622 ? 102.930 124.934 156.881 1.00 162.48 ? 642 ILE B CA  1 
ATOM   10734 C C   . ILE B 1 622 ? 104.153 124.874 157.799 1.00 157.85 ? 642 ILE B C   1 
ATOM   10735 O O   . ILE B 1 622 ? 104.122 125.411 158.906 1.00 155.62 ? 642 ILE B O   1 
ATOM   10736 C CB  . ILE B 1 622 ? 102.012 123.701 157.034 1.00 166.61 ? 642 ILE B CB  1 
ATOM   10737 C CG1 . ILE B 1 622 ? 101.631 123.465 158.499 1.00 168.32 ? 642 ILE B CG1 1 
ATOM   10738 C CG2 . ILE B 1 622 ? 102.630 122.459 156.404 1.00 167.66 ? 642 ILE B CG2 1 
ATOM   10739 C CD1 . ILE B 1 622 ? 100.454 122.531 158.693 1.00 167.56 ? 642 ILE B CD1 1 
ATOM   10740 N N   . TYR B 1 623 ? 105.222 124.212 157.343 1.00 154.91 ? 643 TYR B N   1 
ATOM   10741 C CA  . TYR B 1 623 ? 106.371 123.961 158.198 1.00 154.47 ? 643 TYR B CA  1 
ATOM   10742 C C   . TYR B 1 623 ? 107.213 125.226 158.350 1.00 155.16 ? 643 TYR B C   1 
ATOM   10743 O O   . TYR B 1 623 ? 107.693 125.499 159.446 1.00 157.10 ? 643 TYR B O   1 
ATOM   10744 C CB  . TYR B 1 623 ? 107.171 122.760 157.685 1.00 155.14 ? 643 TYR B CB  1 
ATOM   10745 C CG  . TYR B 1 623 ? 106.619 121.417 158.098 1.00 158.77 ? 643 TYR B CG  1 
ATOM   10746 C CD1 . TYR B 1 623 ? 105.324 121.271 158.574 1.00 161.66 ? 643 TYR B CD1 1 
ATOM   10747 C CD2 . TYR B 1 623 ? 107.416 120.286 158.050 1.00 162.44 ? 643 TYR B CD2 1 
ATOM   10748 C CE1 . TYR B 1 623 ? 104.831 120.036 158.964 1.00 166.83 ? 643 TYR B CE1 1 
ATOM   10749 C CE2 . TYR B 1 623 ? 106.944 119.044 158.445 1.00 166.90 ? 643 TYR B CE2 1 
ATOM   10750 C CZ  . TYR B 1 623 ? 105.643 118.916 158.900 1.00 169.26 ? 643 TYR B CZ  1 
ATOM   10751 O OH  . TYR B 1 623 ? 105.162 117.688 159.289 1.00 168.91 ? 643 TYR B OH  1 
ATOM   10752 N N   . CYS B 1 624 ? 107.381 125.996 157.264 1.00 156.39 ? 644 CYS B N   1 
ATOM   10753 C CA  . CYS B 1 624 ? 108.035 127.295 157.356 1.00 157.82 ? 644 CYS B CA  1 
ATOM   10754 C C   . CYS B 1 624 ? 107.173 128.269 158.164 1.00 154.38 ? 644 CYS B C   1 
ATOM   10755 O O   . CYS B 1 624 ? 107.695 129.202 158.768 1.00 151.62 ? 644 CYS B O   1 
ATOM   10756 C CB  . CYS B 1 624 ? 108.354 127.877 155.979 1.00 161.88 ? 644 CYS B CB  1 
ATOM   10757 S SG  . CYS B 1 624 ? 109.369 126.806 154.923 1.00 167.14 ? 644 CYS B SG  1 
ATOM   10758 N N   . TYR B 1 625 ? 105.848 128.075 158.166 1.00 155.69 ? 645 TYR B N   1 
ATOM   10759 C CA  . TYR B 1 625 ? 104.967 128.855 159.019 1.00 159.21 ? 645 TYR B CA  1 
ATOM   10760 C C   . TYR B 1 625 ? 105.297 128.589 160.488 1.00 152.18 ? 645 TYR B C   1 
ATOM   10761 O O   . TYR B 1 625 ? 105.432 129.525 161.274 1.00 150.35 ? 645 TYR B O   1 
ATOM   10762 C CB  . TYR B 1 625 ? 103.498 128.559 158.698 1.00 166.89 ? 645 TYR B CB  1 
ATOM   10763 C CG  . TYR B 1 625 ? 102.790 129.624 157.900 1.00 174.34 ? 645 TYR B CG  1 
ATOM   10764 C CD1 . TYR B 1 625 ? 103.316 130.129 156.719 1.00 177.05 ? 645 TYR B CD1 1 
ATOM   10765 C CD2 . TYR B 1 625 ? 101.581 130.140 158.338 1.00 178.08 ? 645 TYR B CD2 1 
ATOM   10766 C CE1 . TYR B 1 625 ? 102.662 131.114 155.996 1.00 179.65 ? 645 TYR B CE1 1 
ATOM   10767 C CE2 . TYR B 1 625 ? 100.915 131.127 157.629 1.00 181.02 ? 645 TYR B CE2 1 
ATOM   10768 C CZ  . TYR B 1 625 ? 101.454 131.613 156.451 1.00 182.27 ? 645 TYR B CZ  1 
ATOM   10769 O OH  . TYR B 1 625 ? 100.795 132.591 155.744 1.00 183.09 ? 645 TYR B OH  1 
ATOM   10770 N N   . LEU B 1 626 ? 105.405 127.307 160.850 1.00 146.51 ? 646 LEU B N   1 
ATOM   10771 C CA  . LEU B 1 626 ? 105.530 126.920 162.247 1.00 144.55 ? 646 LEU B CA  1 
ATOM   10772 C C   . LEU B 1 626 ? 106.929 127.222 162.779 1.00 135.69 ? 646 LEU B C   1 
ATOM   10773 O O   . LEU B 1 626 ? 107.071 127.515 163.963 1.00 132.62 ? 646 LEU B O   1 
ATOM   10774 C CB  . LEU B 1 626 ? 105.187 125.432 162.396 1.00 151.74 ? 646 LEU B CB  1 
ATOM   10775 C CG  . LEU B 1 626 ? 103.789 125.137 162.941 1.00 158.48 ? 646 LEU B CG  1 
ATOM   10776 C CD1 . LEU B 1 626 ? 103.633 125.672 164.358 1.00 160.62 ? 646 LEU B CD1 1 
ATOM   10777 C CD2 . LEU B 1 626 ? 102.712 125.716 162.034 1.00 160.76 ? 646 LEU B CD2 1 
ATOM   10778 N N   . GLN B 1 627 ? 107.957 127.120 161.922 1.00 129.51 ? 647 GLN B N   1 
ATOM   10779 C CA  . GLN B 1 627 ? 109.335 127.200 162.388 1.00 124.92 ? 647 GLN B CA  1 
ATOM   10780 C C   . GLN B 1 627 ? 109.609 128.602 162.930 1.00 118.45 ? 647 GLN B C   1 
ATOM   10781 O O   . GLN B 1 627 ? 110.252 128.758 163.966 1.00 118.60 ? 647 GLN B O   1 
ATOM   10782 C CB  . GLN B 1 627 ? 110.323 126.779 161.291 1.00 128.35 ? 647 GLN B CB  1 
ATOM   10783 C CG  . GLN B 1 627 ? 110.810 127.913 160.395 1.00 130.93 ? 647 GLN B CG  1 
ATOM   10784 C CD  . GLN B 1 627 ? 111.788 127.458 159.340 1.00 131.92 ? 647 GLN B CD  1 
ATOM   10785 O OE1 . GLN B 1 627 ? 111.741 126.323 158.872 1.00 130.59 ? 647 GLN B OE1 1 
ATOM   10786 N NE2 . GLN B 1 627 ? 112.670 128.361 158.937 1.00 132.61 ? 647 GLN B NE2 1 
ATOM   10787 N N   . ARG B 1 628 ? 109.103 129.617 162.225 1.00 114.90 ? 648 ARG B N   1 
ATOM   10788 C CA  . ARG B 1 628 ? 109.357 130.996 162.597 1.00 114.86 ? 648 ARG B CA  1 
ATOM   10789 C C   . ARG B 1 628 ? 108.704 131.272 163.946 1.00 114.88 ? 648 ARG B C   1 
ATOM   10790 O O   . ARG B 1 628 ? 109.337 131.856 164.819 1.00 115.30 ? 648 ARG B O   1 
ATOM   10791 C CB  . ARG B 1 628 ? 108.846 131.939 161.506 1.00 117.59 ? 648 ARG B CB  1 
ATOM   10792 C CG  . ARG B 1 628 ? 109.564 133.279 161.453 1.00 119.21 ? 648 ARG B CG  1 
ATOM   10793 C CD  . ARG B 1 628 ? 109.411 133.894 160.078 1.00 120.71 ? 648 ARG B CD  1 
ATOM   10794 N NE  . ARG B 1 628 ? 109.953 135.239 159.988 1.00 121.61 ? 648 ARG B NE  1 
ATOM   10795 C CZ  . ARG B 1 628 ? 109.824 136.030 158.930 1.00 124.00 ? 648 ARG B CZ  1 
ATOM   10796 N NH1 . ARG B 1 628 ? 109.169 135.615 157.857 1.00 125.76 ? 648 ARG B NH1 1 
ATOM   10797 N NH2 . ARG B 1 628 ? 110.340 137.247 158.951 1.00 124.71 ? 648 ARG B NH2 1 
ATOM   10798 N N   . ILE B 1 629 ? 107.456 130.817 164.114 1.00 114.59 ? 649 ILE B N   1 
ATOM   10799 C CA  . ILE B 1 629 ? 106.708 131.071 165.337 1.00 113.27 ? 649 ILE B CA  1 
ATOM   10800 C C   . ILE B 1 629 ? 107.437 130.399 166.497 1.00 108.98 ? 649 ILE B C   1 
ATOM   10801 O O   . ILE B 1 629 ? 107.648 131.029 167.528 1.00 109.21 ? 649 ILE B O   1 
ATOM   10802 C CB  . ILE B 1 629 ? 105.238 130.606 165.227 1.00 114.40 ? 649 ILE B CB  1 
ATOM   10803 C CG1 . ILE B 1 629 ? 104.586 131.073 163.922 1.00 116.11 ? 649 ILE B CG1 1 
ATOM   10804 C CG2 . ILE B 1 629 ? 104.427 131.040 166.447 1.00 114.24 ? 649 ILE B CG2 1 
ATOM   10805 C CD1 . ILE B 1 629 ? 104.706 132.560 163.672 1.00 116.74 ? 649 ILE B CD1 1 
ATOM   10806 N N   . GLY B 1 630 ? 107.831 129.132 166.313 1.00 104.07 ? 650 GLY B N   1 
ATOM   10807 C CA  . GLY B 1 630 ? 108.515 128.388 167.358 1.00 100.03 ? 650 GLY B CA  1 
ATOM   10808 C C   . GLY B 1 630 ? 109.799 129.084 167.807 1.00 95.84  ? 650 GLY B C   1 
ATOM   10809 O O   . GLY B 1 630 ? 109.997 129.337 168.997 1.00 95.82  ? 650 GLY B O   1 
ATOM   10810 N N   . ILE B 1 631 ? 110.654 129.407 166.833 1.00 94.56  ? 651 ILE B N   1 
ATOM   10811 C CA  . ILE B 1 631 ? 111.975 129.955 167.105 1.00 95.05  ? 651 ILE B CA  1 
ATOM   10812 C C   . ILE B 1 631 ? 111.843 131.316 167.783 1.00 97.12  ? 651 ILE B C   1 
ATOM   10813 O O   . ILE B 1 631 ? 112.590 131.622 168.707 1.00 97.19  ? 651 ILE B O   1 
ATOM   10814 C CB  . ILE B 1 631 ? 112.812 130.031 165.810 1.00 94.53  ? 651 ILE B CB  1 
ATOM   10815 C CG1 . ILE B 1 631 ? 113.489 128.693 165.500 1.00 93.57  ? 651 ILE B CG1 1 
ATOM   10816 C CG2 . ILE B 1 631 ? 113.832 131.158 165.878 1.00 94.30  ? 651 ILE B CG2 1 
ATOM   10817 C CD1 . ILE B 1 631 ? 113.596 128.381 164.022 1.00 93.71  ? 651 ILE B CD1 1 
ATOM   10818 N N   . GLY B 1 632 ? 110.903 132.137 167.307 1.00 101.60 ? 652 GLY B N   1 
ATOM   10819 C CA  . GLY B 1 632 ? 110.737 133.482 167.831 1.00 104.37 ? 652 GLY B CA  1 
ATOM   10820 C C   . GLY B 1 632 ? 110.014 133.502 169.177 1.00 106.13 ? 652 GLY B C   1 
ATOM   10821 O O   . GLY B 1 632 ? 110.145 134.461 169.934 1.00 105.55 ? 652 GLY B O   1 
ATOM   10822 N N   . LEU B 1 633 ? 109.225 132.461 169.462 1.00 108.09 ? 653 LEU B N   1 
ATOM   10823 C CA  . LEU B 1 633 ? 108.260 132.489 170.549 1.00 109.22 ? 653 LEU B CA  1 
ATOM   10824 C C   . LEU B 1 633 ? 108.818 131.812 171.798 1.00 105.44 ? 653 LEU B C   1 
ATOM   10825 O O   . LEU B 1 633 ? 108.690 132.351 172.895 1.00 107.16 ? 653 LEU B O   1 
ATOM   10826 C CB  . LEU B 1 633 ? 106.980 131.822 170.036 1.00 112.60 ? 653 LEU B CB  1 
ATOM   10827 C CG  . LEU B 1 633 ? 105.973 131.319 171.064 1.00 114.65 ? 653 LEU B CG  1 
ATOM   10828 C CD1 . LEU B 1 633 ? 105.598 132.402 172.066 1.00 115.46 ? 653 LEU B CD1 1 
ATOM   10829 C CD2 . LEU B 1 633 ? 104.741 130.802 170.335 1.00 116.33 ? 653 LEU B CD2 1 
ATOM   10830 N N   . SER B 1 634 ? 109.446 130.641 171.634 1.00 101.58 ? 654 SER B N   1 
ATOM   10831 C CA  . SER B 1 634 ? 109.851 129.842 172.780 1.00 101.29 ? 654 SER B CA  1 
ATOM   10832 C C   . SER B 1 634 ? 110.773 130.641 173.706 1.00 101.13 ? 654 SER B C   1 
ATOM   10833 O O   . SER B 1 634 ? 110.514 130.734 174.910 1.00 101.88 ? 654 SER B O   1 
ATOM   10834 C CB  . SER B 1 634 ? 110.446 128.512 172.369 1.00 99.81  ? 654 SER B CB  1 
ATOM   10835 O OG  . SER B 1 634 ? 111.216 128.584 171.182 1.00 98.48  ? 654 SER B OG  1 
ATOM   10836 N N   . PRO B 1 635 ? 111.863 131.263 173.200 1.00 100.85 ? 655 PRO B N   1 
ATOM   10837 C CA  . PRO B 1 635 ? 112.755 132.028 174.067 1.00 102.22 ? 655 PRO B CA  1 
ATOM   10838 C C   . PRO B 1 635 ? 112.002 133.168 174.739 1.00 107.80 ? 655 PRO B C   1 
ATOM   10839 O O   . PRO B 1 635 ? 112.306 133.492 175.880 1.00 109.74 ? 655 PRO B O   1 
ATOM   10840 C CB  . PRO B 1 635 ? 113.851 132.573 173.143 1.00 100.50 ? 655 PRO B CB  1 
ATOM   10841 C CG  . PRO B 1 635 ? 113.749 131.729 171.897 1.00 101.40 ? 655 PRO B CG  1 
ATOM   10842 C CD  . PRO B 1 635 ? 112.300 131.303 171.798 1.00 101.29 ? 655 PRO B CD  1 
ATOM   10843 N N   . ALA B 1 636 ? 111.020 133.750 174.039 1.00 111.93 ? 656 ALA B N   1 
ATOM   10844 C CA  . ALA B 1 636 ? 110.248 134.851 174.590 1.00 114.08 ? 656 ALA B CA  1 
ATOM   10845 C C   . ALA B 1 636 ? 109.581 134.429 175.897 1.00 115.24 ? 656 ALA B C   1 
ATOM   10846 O O   . ALA B 1 636 ? 109.750 135.091 176.920 1.00 114.89 ? 656 ALA B O   1 
ATOM   10847 C CB  . ALA B 1 636 ? 109.244 135.339 173.576 1.00 113.95 ? 656 ALA B CB  1 
ATOM   10848 N N   . MET B 1 637 ? 108.853 133.309 175.869 1.00 114.26 ? 657 MET B N   1 
ATOM   10849 C CA  . MET B 1 637 ? 108.089 132.896 177.035 1.00 115.20 ? 657 MET B CA  1 
ATOM   10850 C C   . MET B 1 637 ? 109.039 132.446 178.142 1.00 111.76 ? 657 MET B C   1 
ATOM   10851 O O   . MET B 1 637 ? 108.851 132.813 179.306 1.00 112.51 ? 657 MET B O   1 
ATOM   10852 C CB  . MET B 1 637 ? 107.105 131.777 176.692 1.00 118.60 ? 657 MET B CB  1 
ATOM   10853 C CG  . MET B 1 637 ? 106.155 132.150 175.569 1.00 121.30 ? 657 MET B CG  1 
ATOM   10854 S SD  . MET B 1 637 ? 104.860 130.917 175.249 1.00 129.68 ? 657 MET B SD  1 
ATOM   10855 C CE  . MET B 1 637 ? 105.638 129.402 175.809 1.00 129.39 ? 657 MET B CE  1 
ATOM   10856 N N   . SER B 1 638 ? 110.065 131.673 177.776 1.00 106.03 ? 658 SER B N   1 
ATOM   10857 C CA  . SER B 1 638 ? 110.991 131.139 178.761 1.00 103.33 ? 658 SER B CA  1 
ATOM   10858 C C   . SER B 1 638 ? 111.689 132.281 179.495 1.00 100.37 ? 658 SER B C   1 
ATOM   10859 O O   . SER B 1 638 ? 111.625 132.370 180.717 1.00 100.76 ? 658 SER B O   1 
ATOM   10860 C CB  . SER B 1 638 ? 111.987 130.202 178.130 1.00 104.34 ? 658 SER B CB  1 
ATOM   10861 O OG  . SER B 1 638 ? 111.337 129.074 177.558 1.00 103.34 ? 658 SER B OG  1 
ATOM   10862 N N   . TYR B 1 639 ? 112.282 133.208 178.738 1.00 98.13  ? 659 TYR B N   1 
ATOM   10863 C CA  . TYR B 1 639 ? 113.069 134.270 179.343 1.00 98.86  ? 659 TYR B CA  1 
ATOM   10864 C C   . TYR B 1 639 ? 112.174 135.348 179.945 1.00 102.25 ? 659 TYR B C   1 
ATOM   10865 O O   . TYR B 1 639 ? 112.617 136.068 180.832 1.00 104.02 ? 659 TYR B O   1 
ATOM   10866 C CB  . TYR B 1 639 ? 114.070 134.826 178.329 1.00 96.64  ? 659 TYR B CB  1 
ATOM   10867 C CG  . TYR B 1 639 ? 115.054 133.784 177.861 1.00 93.31  ? 659 TYR B CG  1 
ATOM   10868 C CD1 . TYR B 1 639 ? 115.705 132.975 178.778 1.00 91.42  ? 659 TYR B CD1 1 
ATOM   10869 C CD2 . TYR B 1 639 ? 115.319 133.581 176.515 1.00 92.21  ? 659 TYR B CD2 1 
ATOM   10870 C CE1 . TYR B 1 639 ? 116.600 132.001 178.371 1.00 90.27  ? 659 TYR B CE1 1 
ATOM   10871 C CE2 . TYR B 1 639 ? 116.190 132.593 176.090 1.00 91.41  ? 659 TYR B CE2 1 
ATOM   10872 C CZ  . TYR B 1 639 ? 116.849 131.813 177.025 1.00 90.63  ? 659 TYR B CZ  1 
ATOM   10873 O OH  . TYR B 1 639 ? 117.743 130.842 176.652 1.00 91.76  ? 659 TYR B OH  1 
ATOM   10874 N N   . SER B 1 640 ? 110.927 135.470 179.476 1.00 101.32 ? 660 SER B N   1 
ATOM   10875 C CA  . SER B 1 640 ? 110.008 136.443 180.053 1.00 100.09 ? 660 SER B CA  1 
ATOM   10876 C C   . SER B 1 640 ? 109.625 136.015 181.467 1.00 98.98  ? 660 SER B C   1 
ATOM   10877 O O   . SER B 1 640 ? 109.617 136.828 182.393 1.00 98.41  ? 660 SER B O   1 
ATOM   10878 C CB  . SER B 1 640 ? 108.787 136.631 179.206 1.00 100.89 ? 660 SER B CB  1 
ATOM   10879 O OG  . SER B 1 640 ? 108.096 135.403 179.060 1.00 101.65 ? 660 SER B OG  1 
ATOM   10880 N N   . ALA B 1 641 ? 109.335 134.720 181.635 1.00 101.33 ? 661 ALA B N   1 
ATOM   10881 C CA  . ALA B 1 641 ? 109.023 134.187 182.951 1.00 104.92 ? 661 ALA B CA  1 
ATOM   10882 C C   . ALA B 1 641 ? 110.268 134.250 183.838 1.00 105.86 ? 661 ALA B C   1 
ATOM   10883 O O   . ALA B 1 641 ? 110.167 134.572 185.020 1.00 106.58 ? 661 ALA B O   1 
ATOM   10884 C CB  . ALA B 1 641 ? 108.478 132.785 182.841 1.00 106.78 ? 661 ALA B CB  1 
ATOM   10885 N N   . LEU B 1 642 ? 111.445 134.003 183.246 1.00 107.22 ? 662 LEU B N   1 
ATOM   10886 C CA  . LEU B 1 642 ? 112.692 134.070 183.990 1.00 108.88 ? 662 LEU B CA  1 
ATOM   10887 C C   . LEU B 1 642 ? 112.909 135.497 184.493 1.00 109.40 ? 662 LEU B C   1 
ATOM   10888 O O   . LEU B 1 642 ? 113.286 135.696 185.646 1.00 111.06 ? 662 LEU B O   1 
ATOM   10889 C CB  . LEU B 1 642 ? 113.845 133.598 183.097 1.00 110.21 ? 662 LEU B CB  1 
ATOM   10890 C CG  . LEU B 1 642 ? 115.228 133.609 183.747 1.00 112.37 ? 662 LEU B CG  1 
ATOM   10891 C CD1 . LEU B 1 642 ? 115.264 132.679 184.947 1.00 111.77 ? 662 LEU B CD1 1 
ATOM   10892 C CD2 . LEU B 1 642 ? 116.311 133.244 182.743 1.00 114.03 ? 662 LEU B CD2 1 
ATOM   10893 N N   . VAL B 1 643 ? 112.669 136.490 183.631 1.00 109.80 ? 663 VAL B N   1 
ATOM   10894 C CA  . VAL B 1 643 ? 112.957 137.867 183.994 1.00 112.50 ? 663 VAL B CA  1 
ATOM   10895 C C   . VAL B 1 643 ? 111.976 138.314 185.076 1.00 115.60 ? 663 VAL B C   1 
ATOM   10896 O O   . VAL B 1 643 ? 112.373 139.032 185.983 1.00 115.57 ? 663 VAL B O   1 
ATOM   10897 C CB  . VAL B 1 643 ? 112.983 138.814 182.777 1.00 113.39 ? 663 VAL B CB  1 
ATOM   10898 C CG1 . VAL B 1 643 ? 111.607 139.058 182.176 1.00 113.50 ? 663 VAL B CG1 1 
ATOM   10899 C CG2 . VAL B 1 643 ? 113.660 140.135 183.114 1.00 113.55 ? 663 VAL B CG2 1 
ATOM   10900 N N   . THR B 1 644 ? 110.712 137.885 184.998 1.00 118.63 ? 664 THR B N   1 
ATOM   10901 C CA  . THR B 1 644 ? 109.725 138.243 186.008 1.00 120.54 ? 664 THR B CA  1 
ATOM   10902 C C   . THR B 1 644 ? 110.091 137.633 187.361 1.00 120.50 ? 664 THR B C   1 
ATOM   10903 O O   . THR B 1 644 ? 109.909 138.260 188.408 1.00 120.35 ? 664 THR B O   1 
ATOM   10904 C CB  . THR B 1 644 ? 108.316 137.805 185.591 1.00 123.70 ? 664 THR B CB  1 
ATOM   10905 O OG1 . THR B 1 644 ? 108.341 136.395 185.367 1.00 123.74 ? 664 THR B OG1 1 
ATOM   10906 C CG2 . THR B 1 644 ? 107.829 138.520 184.351 1.00 125.62 ? 664 THR B CG2 1 
ATOM   10907 N N   . LYS B 1 645 ? 110.603 136.397 187.330 1.00 121.41 ? 665 LYS B N   1 
ATOM   10908 C CA  . LYS B 1 645 ? 111.048 135.730 188.542 1.00 123.15 ? 665 LYS B CA  1 
ATOM   10909 C C   . LYS B 1 645 ? 112.207 136.517 189.151 1.00 125.16 ? 665 LYS B C   1 
ATOM   10910 O O   . LYS B 1 645 ? 112.232 136.751 190.347 1.00 125.41 ? 665 LYS B O   1 
ATOM   10911 C CB  . LYS B 1 645 ? 111.439 134.276 188.255 1.00 122.69 ? 665 LYS B CB  1 
ATOM   10912 C CG  . LYS B 1 645 ? 111.474 133.389 189.491 1.00 123.55 ? 665 LYS B CG  1 
ATOM   10913 C CD  . LYS B 1 645 ? 112.019 132.005 189.246 1.00 125.61 ? 665 LYS B CD  1 
ATOM   10914 C CE  . LYS B 1 645 ? 111.835 131.094 190.441 1.00 126.83 ? 665 LYS B CE  1 
ATOM   10915 N NZ  . LYS B 1 645 ? 112.446 131.654 191.672 1.00 127.17 ? 665 LYS B NZ  1 
ATOM   10916 N N   . THR B 1 646 ? 113.151 136.954 188.311 1.00 129.27 ? 666 THR B N   1 
ATOM   10917 C CA  . THR B 1 646 ? 114.277 137.752 188.764 1.00 135.10 ? 666 THR B CA  1 
ATOM   10918 C C   . THR B 1 646 ? 113.794 139.084 189.336 1.00 141.72 ? 666 THR B C   1 
ATOM   10919 O O   . THR B 1 646 ? 114.387 139.579 190.290 1.00 142.88 ? 666 THR B O   1 
ATOM   10920 C CB  . THR B 1 646 ? 115.299 137.973 187.641 1.00 135.15 ? 666 THR B CB  1 
ATOM   10921 O OG1 . THR B 1 646 ? 114.624 138.547 186.521 1.00 133.02 ? 666 THR B OG1 1 
ATOM   10922 C CG2 . THR B 1 646 ? 116.006 136.701 187.230 1.00 135.27 ? 666 THR B CG2 1 
ATOM   10923 N N   . ASN B 1 647 ? 112.724 139.654 188.765 1.00 147.24 ? 667 ASN B N   1 
ATOM   10924 C CA  . ASN B 1 647 ? 112.183 140.908 189.274 1.00 153.02 ? 667 ASN B CA  1 
ATOM   10925 C C   . ASN B 1 647 ? 111.599 140.710 190.675 1.00 156.14 ? 667 ASN B C   1 
ATOM   10926 O O   . ASN B 1 647 ? 111.798 141.550 191.556 1.00 156.40 ? 667 ASN B O   1 
ATOM   10927 C CB  . ASN B 1 647 ? 111.126 141.538 188.359 1.00 154.64 ? 667 ASN B CB  1 
ATOM   10928 C CG  . ASN B 1 647 ? 111.522 141.591 186.900 1.00 155.19 ? 667 ASN B CG  1 
ATOM   10929 O OD1 . ASN B 1 647 ? 110.717 141.268 186.032 1.00 153.21 ? 667 ASN B OD1 1 
ATOM   10930 N ND2 . ASN B 1 647 ? 112.753 141.981 186.617 1.00 156.62 ? 667 ASN B ND2 1 
ATOM   10931 N N   . ARG B 1 648 ? 110.878 139.601 190.887 1.00 159.18 ? 668 ARG B N   1 
ATOM   10932 C CA  . ARG B 1 648 ? 110.298 139.345 192.196 1.00 162.99 ? 668 ARG B CA  1 
ATOM   10933 C C   . ARG B 1 648 ? 111.419 139.154 193.220 1.00 166.08 ? 668 ARG B C   1 
ATOM   10934 O O   . ARG B 1 648 ? 111.334 139.659 194.335 1.00 168.52 ? 668 ARG B O   1 
ATOM   10935 C CB  . ARG B 1 648 ? 109.343 138.147 192.161 1.00 163.69 ? 668 ARG B CB  1 
ATOM   10936 C CG  . ARG B 1 648 ? 108.576 137.951 193.460 1.00 164.99 ? 668 ARG B CG  1 
ATOM   10937 C CD  . ARG B 1 648 ? 107.631 136.759 193.426 1.00 167.12 ? 668 ARG B CD  1 
ATOM   10938 N NE  . ARG B 1 648 ? 106.581 136.824 194.438 1.00 168.49 ? 668 ARG B NE  1 
ATOM   10939 C CZ  . ARG B 1 648 ? 106.763 136.699 195.752 1.00 170.13 ? 668 ARG B CZ  1 
ATOM   10940 N NH1 . ARG B 1 648 ? 107.971 136.499 196.250 1.00 170.37 ? 668 ARG B NH1 1 
ATOM   10941 N NH2 . ARG B 1 648 ? 105.727 136.777 196.570 1.00 170.75 ? 668 ARG B NH2 1 
ATOM   10942 N N   . ILE B 1 649 ? 112.483 138.444 192.827 1.00 167.59 ? 669 ILE B N   1 
ATOM   10943 C CA  . ILE B 1 649 ? 113.621 138.213 193.704 1.00 170.24 ? 669 ILE B CA  1 
ATOM   10944 C C   . ILE B 1 649 ? 114.288 139.549 194.027 1.00 171.70 ? 669 ILE B C   1 
ATOM   10945 O O   . ILE B 1 649 ? 114.612 139.805 195.182 1.00 173.28 ? 669 ILE B O   1 
ATOM   10946 C CB  . ILE B 1 649 ? 114.600 137.193 193.081 1.00 170.53 ? 669 ILE B CB  1 
ATOM   10947 C CG1 . ILE B 1 649 ? 113.945 135.813 192.960 1.00 170.15 ? 669 ILE B CG1 1 
ATOM   10948 C CG2 . ILE B 1 649 ? 115.909 137.124 193.861 1.00 170.44 ? 669 ILE B CG2 1 
ATOM   10949 C CD1 . ILE B 1 649 ? 114.689 134.837 192.073 1.00 170.04 ? 669 ILE B CD1 1 
ATOM   10950 N N   . ALA B 1 650 ? 114.474 140.397 193.010 1.00 173.17 ? 670 ALA B N   1 
ATOM   10951 C CA  . ALA B 1 650 ? 115.142 141.677 193.190 1.00 178.37 ? 670 ALA B CA  1 
ATOM   10952 C C   . ALA B 1 650 ? 114.310 142.611 194.069 1.00 183.81 ? 670 ALA B C   1 
ATOM   10953 O O   . ALA B 1 650 ? 114.877 143.432 194.787 1.00 183.38 ? 670 ALA B O   1 
ATOM   10954 C CB  . ALA B 1 650 ? 115.442 142.305 191.852 1.00 178.01 ? 670 ALA B CB  1 
ATOM   10955 N N   . ARG B 1 651 ? 112.976 142.486 194.020 1.00 189.48 ? 671 ARG B N   1 
ATOM   10956 C CA  . ARG B 1 651 ? 112.100 143.275 194.876 1.00 195.04 ? 671 ARG B CA  1 
ATOM   10957 C C   . ARG B 1 651 ? 112.223 142.822 196.333 1.00 197.62 ? 671 ARG B C   1 
ATOM   10958 O O   . ARG B 1 651 ? 112.308 143.655 197.232 1.00 198.22 ? 671 ARG B O   1 
ATOM   10959 C CB  . ARG B 1 651 ? 110.645 143.181 194.402 1.00 197.90 ? 671 ARG B CB  1 
ATOM   10960 C CG  . ARG B 1 651 ? 110.352 143.936 193.113 1.00 200.80 ? 671 ARG B CG  1 
ATOM   10961 C CD  . ARG B 1 651 ? 108.871 144.249 192.970 1.00 203.08 ? 671 ARG B CD  1 
ATOM   10962 N NE  . ARG B 1 651 ? 108.029 143.060 192.895 1.00 204.01 ? 671 ARG B NE  1 
ATOM   10963 C CZ  . ARG B 1 651 ? 107.993 142.212 191.870 1.00 203.58 ? 671 ARG B CZ  1 
ATOM   10964 N NH1 . ARG B 1 651 ? 108.687 142.453 190.772 1.00 201.59 ? 671 ARG B NH1 1 
ATOM   10965 N NH2 . ARG B 1 651 ? 107.239 141.128 191.941 1.00 204.28 ? 671 ARG B NH2 1 
ATOM   10966 N N   . ILE B 1 652 ? 112.237 141.500 196.555 1.00 201.66 ? 672 ILE B N   1 
ATOM   10967 C CA  . ILE B 1 652 ? 112.435 140.935 197.882 1.00 206.90 ? 672 ILE B CA  1 
ATOM   10968 C C   . ILE B 1 652 ? 113.776 141.409 198.445 1.00 207.56 ? 672 ILE B C   1 
ATOM   10969 O O   . ILE B 1 652 ? 113.901 141.636 199.648 1.00 206.23 ? 672 ILE B O   1 
ATOM   10970 C CB  . ILE B 1 652 ? 112.333 139.393 197.844 1.00 210.15 ? 672 ILE B CB  1 
ATOM   10971 C CG1 . ILE B 1 652 ? 110.921 138.907 197.498 1.00 210.83 ? 672 ILE B CG1 1 
ATOM   10972 C CG2 . ILE B 1 652 ? 112.824 138.766 199.143 1.00 210.36 ? 672 ILE B CG2 1 
ATOM   10973 C CD1 . ILE B 1 652 ? 109.859 139.251 198.520 1.00 210.70 ? 672 ILE B CD1 1 
ATOM   10974 N N   . LEU B 1 653 ? 114.775 141.559 197.565 1.00 209.16 ? 673 LEU B N   1 
ATOM   10975 C CA  . LEU B 1 653 ? 116.082 142.057 197.962 1.00 211.88 ? 673 LEU B CA  1 
ATOM   10976 C C   . LEU B 1 653 ? 116.003 143.552 198.267 1.00 211.95 ? 673 LEU B C   1 
ATOM   10977 O O   . LEU B 1 653 ? 116.614 144.011 199.231 1.00 210.77 ? 673 LEU B O   1 
ATOM   10978 C CB  . LEU B 1 653 ? 117.106 141.786 196.853 1.00 213.53 ? 673 LEU B CB  1 
ATOM   10979 C CG  . LEU B 1 653 ? 117.550 140.335 196.674 1.00 214.48 ? 673 LEU B CG  1 
ATOM   10980 C CD1 . LEU B 1 653 ? 118.435 140.196 195.443 1.00 215.13 ? 673 LEU B CD1 1 
ATOM   10981 C CD2 . LEU B 1 653 ? 118.281 139.814 197.905 1.00 213.70 ? 673 LEU B CD2 1 
ATOM   10982 N N   . ALA B 1 654 ? 115.260 144.303 197.440 1.00 212.79 ? 674 ALA B N   1 
ATOM   10983 C CA  . ALA B 1 654 ? 115.152 145.746 197.595 1.00 213.73 ? 674 ALA B CA  1 
ATOM   10984 C C   . ALA B 1 654 ? 114.498 146.094 198.932 1.00 216.17 ? 674 ALA B C   1 
ATOM   10985 O O   . ALA B 1 654 ? 114.778 147.147 199.503 1.00 216.06 ? 674 ALA B O   1 
ATOM   10986 C CB  . ALA B 1 654 ? 114.389 146.342 196.437 1.00 212.33 ? 674 ALA B CB  1 
ATOM   10987 N N   . GLY B 1 655 ? 113.620 145.208 199.421 1.00 217.09 ? 675 GLY B N   1 
ATOM   10988 C CA  . GLY B 1 655 ? 113.061 145.332 200.758 1.00 216.91 ? 675 GLY B CA  1 
ATOM   10989 C C   . GLY B 1 655 ? 114.131 145.286 201.839 1.00 215.64 ? 675 GLY B C   1 
ATOM   10990 O O   . GLY B 1 655 ? 114.091 146.166 202.729 1.00 212.48 ? 675 GLY B O   1 
ATOM   10991 N N   . MET B 1 668 ? 103.957 144.688 195.570 1.00 214.87 ? 688 MET B N   1 
ATOM   10992 C CA  . MET B 1 668 ? 103.173 144.450 194.328 1.00 216.72 ? 688 MET B CA  1 
ATOM   10993 C C   . MET B 1 668 ? 103.058 142.950 194.059 1.00 217.45 ? 688 MET B C   1 
ATOM   10994 O O   . MET B 1 668 ? 101.996 142.386 194.307 1.00 217.01 ? 688 MET B O   1 
ATOM   10995 C CB  . MET B 1 668 ? 103.809 145.151 193.124 1.00 217.00 ? 688 MET B CB  1 
ATOM   10996 C CG  . MET B 1 668 ? 102.834 145.975 192.298 1.00 215.56 ? 688 MET B CG  1 
ATOM   10997 S SD  . MET B 1 668 ? 103.072 145.822 190.496 1.00 213.41 ? 688 MET B SD  1 
ATOM   10998 C CE  . MET B 1 668 ? 104.108 144.360 190.397 1.00 214.10 ? 688 MET B CE  1 
ATOM   10999 N N   . SER B 1 669 ? 104.148 142.317 193.580 1.00 216.60 ? 689 SER B N   1 
ATOM   11000 C CA  . SER B 1 669 ? 104.247 140.872 193.370 1.00 215.22 ? 689 SER B CA  1 
ATOM   11001 C C   . SER B 1 669 ? 102.880 140.228 193.118 1.00 213.01 ? 689 SER B C   1 
ATOM   11002 O O   . SER B 1 669 ? 102.219 140.571 192.145 1.00 209.95 ? 689 SER B O   1 
ATOM   11003 C CB  . SER B 1 669 ? 104.971 140.222 194.524 1.00 215.08 ? 689 SER B CB  1 
ATOM   11004 O OG  . SER B 1 669 ? 104.174 140.242 195.700 1.00 214.67 ? 689 SER B OG  1 
ATOM   11005 N N   . ALA B 1 670 ? 102.476 139.271 193.972 1.00 211.78 ? 690 ALA B N   1 
ATOM   11006 C CA  . ALA B 1 670 ? 101.149 138.678 193.940 1.00 211.94 ? 690 ALA B CA  1 
ATOM   11007 C C   . ALA B 1 670 ? 100.906 137.998 192.592 1.00 211.23 ? 690 ALA B C   1 
ATOM   11008 O O   . ALA B 1 670 ? 101.535 136.984 192.292 1.00 208.64 ? 690 ALA B O   1 
ATOM   11009 C CB  . ALA B 1 670 ? 100.111 139.730 194.260 1.00 211.60 ? 690 ALA B CB  1 
ATOM   11010 N N   . CYS B 1 671 ? 99.963  138.532 191.804 1.00 211.33 ? 691 CYS B N   1 
ATOM   11011 C CA  . CYS B 1 671 ? 99.581  137.928 190.540 1.00 211.62 ? 691 CYS B CA  1 
ATOM   11012 C C   . CYS B 1 671 ? 99.817  138.883 189.369 1.00 211.38 ? 691 CYS B C   1 
ATOM   11013 O O   . CYS B 1 671 ? 99.520  138.525 188.233 1.00 210.63 ? 691 CYS B O   1 
ATOM   11014 C CB  . CYS B 1 671 ? 98.121  137.483 190.570 1.00 211.45 ? 691 CYS B CB  1 
ATOM   11015 S SG  . CYS B 1 671 ? 96.958  138.821 190.948 1.00 208.57 ? 691 CYS B SG  1 
ATOM   11016 N N   . ALA B 1 672 ? 100.359 140.081 189.635 1.00 210.88 ? 692 ALA B N   1 
ATOM   11017 C CA  . ALA B 1 672 ? 100.617 141.056 188.586 1.00 210.69 ? 692 ALA B CA  1 
ATOM   11018 C C   . ALA B 1 672 ? 101.728 140.556 187.663 1.00 208.61 ? 692 ALA B C   1 
ATOM   11019 O O   . ALA B 1 672 ? 101.731 140.864 186.474 1.00 206.48 ? 692 ALA B O   1 
ATOM   11020 C CB  . ALA B 1 672 ? 100.966 142.392 189.196 1.00 210.32 ? 692 ALA B CB  1 
ATOM   11021 N N   . GLN B 1 673 ? 102.669 139.787 188.225 1.00 205.27 ? 693 GLN B N   1 
ATOM   11022 C CA  . GLN B 1 673 ? 103.793 139.257 187.471 1.00 202.20 ? 693 GLN B CA  1 
ATOM   11023 C C   . GLN B 1 673 ? 103.305 138.422 186.284 1.00 202.11 ? 693 GLN B C   1 
ATOM   11024 O O   . GLN B 1 673 ? 103.929 138.460 185.234 1.00 200.05 ? 693 GLN B O   1 
ATOM   11025 C CB  . GLN B 1 673 ? 104.768 138.508 188.386 1.00 199.80 ? 693 GLN B CB  1 
ATOM   11026 C CG  . GLN B 1 673 ? 104.157 137.403 189.236 1.00 199.02 ? 693 GLN B CG  1 
ATOM   11027 C CD  . GLN B 1 673 ? 105.163 136.857 190.224 1.00 196.32 ? 693 GLN B CD  1 
ATOM   11028 O OE1 . GLN B 1 673 ? 105.765 137.598 190.998 1.00 192.61 ? 693 GLN B OE1 1 
ATOM   11029 N NE2 . GLN B 1 673 ? 105.369 135.550 190.194 1.00 194.32 ? 693 GLN B NE2 1 
ATOM   11030 N N   . LEU B 1 674 ? 102.179 137.713 186.423 1.00 201.92 ? 694 LEU B N   1 
ATOM   11031 C CA  . LEU B 1 674 ? 101.609 136.973 185.304 1.00 200.78 ? 694 LEU B CA  1 
ATOM   11032 C C   . LEU B 1 674 ? 101.232 137.915 184.159 1.00 198.66 ? 694 LEU B C   1 
ATOM   11033 O O   . LEU B 1 674 ? 101.487 137.624 182.991 1.00 198.33 ? 694 LEU B O   1 
ATOM   11034 C CB  . LEU B 1 674 ? 100.391 136.170 185.781 1.00 200.87 ? 694 LEU B CB  1 
ATOM   11035 C CG  . LEU B 1 674 ? 100.664 134.719 186.185 1.00 201.19 ? 694 LEU B CG  1 
ATOM   11036 C CD1 . LEU B 1 674 ? 101.056 133.869 184.983 1.00 201.55 ? 694 LEU B CD1 1 
ATOM   11037 C CD2 . LEU B 1 674 ? 101.741 134.642 187.258 1.00 199.80 ? 694 LEU B CD2 1 
ATOM   11038 N N   . VAL B 1 675 ? 100.643 139.064 184.500 1.00 199.07 ? 695 VAL B N   1 
ATOM   11039 C CA  . VAL B 1 675 ? 100.164 140.005 183.499 1.00 201.66 ? 695 VAL B CA  1 
ATOM   11040 C C   . VAL B 1 675 ? 101.366 140.682 182.835 1.00 197.18 ? 695 VAL B C   1 
ATOM   11041 O O   . VAL B 1 675 ? 101.326 140.997 181.644 1.00 195.75 ? 695 VAL B O   1 
ATOM   11042 C CB  . VAL B 1 675 ? 99.190  141.036 184.108 1.00 208.30 ? 695 VAL B CB  1 
ATOM   11043 C CG1 . VAL B 1 675 ? 98.608  141.966 183.053 1.00 208.94 ? 695 VAL B CG1 1 
ATOM   11044 C CG2 . VAL B 1 675 ? 98.071  140.366 184.897 1.00 209.27 ? 695 VAL B CG2 1 
ATOM   11045 N N   . ILE B 1 676 ? 102.441 140.907 183.605 1.00 194.79 ? 696 ILE B N   1 
ATOM   11046 C CA  . ILE B 1 676 ? 103.614 141.551 183.040 1.00 196.25 ? 696 ILE B CA  1 
ATOM   11047 C C   . ILE B 1 676 ? 104.295 140.570 182.082 1.00 193.24 ? 696 ILE B C   1 
ATOM   11048 O O   . ILE B 1 676 ? 104.713 140.963 180.999 1.00 190.49 ? 696 ILE B O   1 
ATOM   11049 C CB  . ILE B 1 676 ? 104.547 142.146 184.114 1.00 200.38 ? 696 ILE B CB  1 
ATOM   11050 C CG1 . ILE B 1 676 ? 105.381 141.084 184.830 1.00 204.02 ? 696 ILE B CG1 1 
ATOM   11051 C CG2 . ILE B 1 676 ? 103.750 143.019 185.078 1.00 199.16 ? 696 ILE B CG2 1 
ATOM   11052 C CD1 . ILE B 1 676 ? 106.397 141.645 185.803 1.00 206.41 ? 696 ILE B CD1 1 
ATOM   11053 N N   . ALA B 1 677 ? 104.370 139.288 182.457 1.00 191.31 ? 697 ALA B N   1 
ATOM   11054 C CA  . ALA B 1 677 ? 104.897 138.265 181.565 1.00 189.44 ? 697 ALA B CA  1 
ATOM   11055 C C   . ALA B 1 677 ? 104.049 138.197 180.295 1.00 189.51 ? 697 ALA B C   1 
ATOM   11056 O O   . ALA B 1 677 ? 104.587 138.063 179.199 1.00 186.26 ? 697 ALA B O   1 
ATOM   11057 C CB  . ALA B 1 677 ? 104.947 136.927 182.266 1.00 187.85 ? 697 ALA B CB  1 
ATOM   11058 N N   . PHE B 1 678 ? 102.725 138.320 180.450 1.00 192.74 ? 698 PHE B N   1 
ATOM   11059 C CA  . PHE B 1 678 ? 101.804 138.206 179.331 1.00 195.29 ? 698 PHE B CA  1 
ATOM   11060 C C   . PHE B 1 678 ? 101.952 139.391 178.372 1.00 189.04 ? 698 PHE B C   1 
ATOM   11061 O O   . PHE B 1 678 ? 101.861 139.214 177.159 1.00 186.32 ? 698 PHE B O   1 
ATOM   11062 C CB  . PHE B 1 678 ? 100.359 138.092 179.825 1.00 203.40 ? 698 PHE B CB  1 
ATOM   11063 C CG  . PHE B 1 678 ? 99.361  137.782 178.739 1.00 212.63 ? 698 PHE B CG  1 
ATOM   11064 C CD1 . PHE B 1 678 ? 99.385  136.556 178.093 1.00 216.08 ? 698 PHE B CD1 1 
ATOM   11065 C CD2 . PHE B 1 678 ? 98.413  138.718 178.345 1.00 216.17 ? 698 PHE B CD2 1 
ATOM   11066 C CE1 . PHE B 1 678 ? 98.474  136.265 177.088 1.00 218.22 ? 698 PHE B CE1 1 
ATOM   11067 C CE2 . PHE B 1 678 ? 97.505  138.426 177.339 1.00 218.00 ? 698 PHE B CE2 1 
ATOM   11068 C CZ  . PHE B 1 678 ? 97.536  137.201 176.712 1.00 219.12 ? 698 PHE B CZ  1 
ATOM   11069 N N   . ILE B 1 679 ? 102.166 140.602 178.904 1.00 186.82 ? 699 ILE B N   1 
ATOM   11070 C CA  . ILE B 1 679 ? 102.325 141.764 178.041 1.00 187.18 ? 699 ILE B CA  1 
ATOM   11071 C C   . ILE B 1 679 ? 103.673 141.688 177.321 1.00 182.06 ? 699 ILE B C   1 
ATOM   11072 O O   . ILE B 1 679 ? 103.792 142.148 176.188 1.00 181.61 ? 699 ILE B O   1 
ATOM   11073 C CB  . ILE B 1 679 ? 102.132 143.095 178.798 1.00 191.95 ? 699 ILE B CB  1 
ATOM   11074 C CG1 . ILE B 1 679 ? 103.176 143.300 179.898 1.00 191.26 ? 699 ILE B CG1 1 
ATOM   11075 C CG2 . ILE B 1 679 ? 100.708 143.206 179.325 1.00 194.44 ? 699 ILE B CG2 1 
ATOM   11076 C CD1 . ILE B 1 679 ? 103.064 144.618 180.632 1.00 190.60 ? 699 ILE B CD1 1 
ATOM   11077 N N   . LEU B 1 680 ? 104.685 141.096 177.964 1.00 176.54 ? 700 LEU B N   1 
ATOM   11078 C CA  . LEU B 1 680 ? 105.967 140.879 177.307 1.00 172.25 ? 700 LEU B CA  1 
ATOM   11079 C C   . LEU B 1 680 ? 105.783 139.918 176.129 1.00 168.16 ? 700 LEU B C   1 
ATOM   11080 O O   . LEU B 1 680 ? 106.266 140.182 175.034 1.00 166.18 ? 700 LEU B O   1 
ATOM   11081 C CB  . LEU B 1 680 ? 106.984 140.350 178.324 1.00 172.14 ? 700 LEU B CB  1 
ATOM   11082 C CG  . LEU B 1 680 ? 108.383 140.946 178.194 1.00 172.74 ? 700 LEU B CG  1 
ATOM   11083 C CD1 . LEU B 1 680 ? 108.405 142.383 178.695 1.00 173.74 ? 700 LEU B CD1 1 
ATOM   11084 C CD2 . LEU B 1 680 ? 109.405 140.109 178.942 1.00 171.65 ? 700 LEU B CD2 1 
ATOM   11085 N N   . ILE B 1 681 ? 105.054 138.819 176.342 1.00 165.62 ? 701 ILE B N   1 
ATOM   11086 C CA  . ILE B 1 681 ? 104.763 137.873 175.273 1.00 164.36 ? 701 ILE B CA  1 
ATOM   11087 C C   . ILE B 1 681 ? 103.916 138.554 174.196 1.00 166.11 ? 701 ILE B C   1 
ATOM   11088 O O   . ILE B 1 681 ? 104.045 138.232 173.016 1.00 163.06 ? 701 ILE B O   1 
ATOM   11089 C CB  . ILE B 1 681 ? 104.067 136.610 175.828 1.00 164.22 ? 701 ILE B CB  1 
ATOM   11090 C CG1 . ILE B 1 681 ? 104.898 135.938 176.923 1.00 163.26 ? 701 ILE B CG1 1 
ATOM   11091 C CG2 . ILE B 1 681 ? 103.714 135.629 174.715 1.00 163.28 ? 701 ILE B CG2 1 
ATOM   11092 C CD1 . ILE B 1 681 ? 106.321 135.637 176.521 1.00 160.97 ? 701 ILE B CD1 1 
ATOM   11093 N N   . CYS B 1 682 ? 103.041 139.480 174.612 1.00 171.05 ? 702 CYS B N   1 
ATOM   11094 C CA  . CYS B 1 682 ? 102.169 140.182 173.683 1.00 175.28 ? 702 CYS B CA  1 
ATOM   11095 C C   . CYS B 1 682 ? 102.988 141.055 172.730 1.00 173.69 ? 702 CYS B C   1 
ATOM   11096 O O   . CYS B 1 682 ? 102.727 141.062 171.526 1.00 175.01 ? 702 CYS B O   1 
ATOM   11097 C CB  . CYS B 1 682 ? 101.116 141.021 174.399 1.00 179.63 ? 702 CYS B CB  1 
ATOM   11098 S SG  . CYS B 1 682 ? 99.745  140.049 175.078 1.00 186.39 ? 702 CYS B SG  1 
ATOM   11099 N N   . ILE B 1 683 ? 103.977 141.787 173.259 1.00 170.54 ? 703 ILE B N   1 
ATOM   11100 C CA  . ILE B 1 683 ? 104.799 142.639 172.413 1.00 168.59 ? 703 ILE B CA  1 
ATOM   11101 C C   . ILE B 1 683 ? 105.627 141.758 171.478 1.00 166.06 ? 703 ILE B C   1 
ATOM   11102 O O   . ILE B 1 683 ? 105.808 142.110 170.315 1.00 163.41 ? 703 ILE B O   1 
ATOM   11103 C CB  . ILE B 1 683 ? 105.672 143.623 173.222 1.00 169.13 ? 703 ILE B CB  1 
ATOM   11104 C CG1 . ILE B 1 683 ? 106.317 144.671 172.310 1.00 170.79 ? 703 ILE B CG1 1 
ATOM   11105 C CG2 . ILE B 1 683 ? 106.714 142.892 174.054 1.00 168.08 ? 703 ILE B CG2 1 
ATOM   11106 C CD1 . ILE B 1 683 ? 106.972 145.822 173.047 1.00 171.78 ? 703 ILE B CD1 1 
ATOM   11107 N N   . GLN B 1 684 ? 106.098 140.606 171.980 1.00 166.03 ? 704 GLN B N   1 
ATOM   11108 C CA  . GLN B 1 684 ? 106.845 139.670 171.152 1.00 166.22 ? 704 GLN B CA  1 
ATOM   11109 C C   . GLN B 1 684 ? 105.966 139.211 169.992 1.00 169.27 ? 704 GLN B C   1 
ATOM   11110 O O   . GLN B 1 684 ? 106.423 139.230 168.848 1.00 171.03 ? 704 GLN B O   1 
ATOM   11111 C CB  . GLN B 1 684 ? 107.352 138.460 171.945 1.00 163.20 ? 704 GLN B CB  1 
ATOM   11112 C CG  . GLN B 1 684 ? 108.506 137.716 171.261 1.00 157.90 ? 704 GLN B CG  1 
ATOM   11113 C CD  . GLN B 1 684 ? 108.076 136.835 170.109 1.00 153.54 ? 704 GLN B CD  1 
ATOM   11114 O OE1 . GLN B 1 684 ? 107.015 136.218 170.150 1.00 150.83 ? 704 GLN B OE1 1 
ATOM   11115 N NE2 . GLN B 1 684 ? 108.864 136.806 169.044 1.00 151.81 ? 704 GLN B NE2 1 
ATOM   11116 N N   . LEU B 1 685 ? 104.724 138.794 170.291 1.00 169.63 ? 705 LEU B N   1 
ATOM   11117 C CA  . LEU B 1 685 ? 103.877 138.205 169.265 1.00 170.66 ? 705 LEU B CA  1 
ATOM   11118 C C   . LEU B 1 685 ? 103.471 139.278 168.255 1.00 172.45 ? 705 LEU B C   1 
ATOM   11119 O O   . LEU B 1 685 ? 103.386 138.992 167.061 1.00 171.78 ? 705 LEU B O   1 
ATOM   11120 C CB  . LEU B 1 685 ? 102.690 137.442 169.873 1.00 170.87 ? 705 LEU B CB  1 
ATOM   11121 C CG  . LEU B 1 685 ? 101.654 138.197 170.706 1.00 173.04 ? 705 LEU B CG  1 
ATOM   11122 C CD1 . LEU B 1 685 ? 100.573 138.827 169.837 1.00 173.28 ? 705 LEU B CD1 1 
ATOM   11123 C CD2 . LEU B 1 685 ? 101.011 137.262 171.727 1.00 173.96 ? 705 LEU B CD2 1 
ATOM   11124 N N   . GLY B 1 686 ? 103.273 140.516 168.727 1.00 174.79 ? 706 GLY B N   1 
ATOM   11125 C CA  . GLY B 1 686 ? 103.055 141.648 167.839 1.00 176.92 ? 706 GLY B CA  1 
ATOM   11126 C C   . GLY B 1 686 ? 104.196 141.821 166.836 1.00 175.77 ? 706 GLY B C   1 
ATOM   11127 O O   . GLY B 1 686 ? 103.962 141.955 165.635 1.00 176.30 ? 706 GLY B O   1 
ATOM   11128 N N   . ILE B 1 687 ? 105.432 141.805 167.347 1.00 174.20 ? 707 ILE B N   1 
ATOM   11129 C CA  . ILE B 1 687 ? 106.612 142.013 166.521 1.00 176.32 ? 707 ILE B CA  1 
ATOM   11130 C C   . ILE B 1 687 ? 106.720 140.888 165.493 1.00 174.06 ? 707 ILE B C   1 
ATOM   11131 O O   . ILE B 1 687 ? 106.947 141.149 164.312 1.00 174.53 ? 707 ILE B O   1 
ATOM   11132 C CB  . ILE B 1 687 ? 107.883 142.137 167.388 1.00 180.67 ? 707 ILE B CB  1 
ATOM   11133 C CG1 . ILE B 1 687 ? 107.889 143.452 168.174 1.00 184.14 ? 707 ILE B CG1 1 
ATOM   11134 C CG2 . ILE B 1 687 ? 109.140 141.992 166.536 1.00 180.78 ? 707 ILE B CG2 1 
ATOM   11135 C CD1 . ILE B 1 687 ? 108.936 143.528 169.266 1.00 185.60 ? 707 ILE B CD1 1 
ATOM   11136 N N   . ILE B 1 688 ? 106.560 139.639 165.945 1.00 171.00 ? 708 ILE B N   1 
ATOM   11137 C CA  . ILE B 1 688 ? 106.789 138.501 165.067 1.00 169.50 ? 708 ILE B CA  1 
ATOM   11138 C C   . ILE B 1 688 ? 105.696 138.461 164.001 1.00 172.67 ? 708 ILE B C   1 
ATOM   11139 O O   . ILE B 1 688 ? 105.996 138.166 162.850 1.00 170.83 ? 708 ILE B O   1 
ATOM   11140 C CB  . ILE B 1 688 ? 106.933 137.163 165.824 1.00 167.70 ? 708 ILE B CB  1 
ATOM   11141 C CG1 . ILE B 1 688 ? 107.024 135.992 164.838 1.00 166.24 ? 708 ILE B CG1 1 
ATOM   11142 C CG2 . ILE B 1 688 ? 105.820 136.951 166.833 1.00 168.02 ? 708 ILE B CG2 1 
ATOM   11143 C CD1 . ILE B 1 688 ? 107.431 134.674 165.458 1.00 162.67 ? 708 ILE B CD1 1 
ATOM   11144 N N   . VAL B 1 689 ? 104.447 138.769 164.370 1.00 178.69 ? 709 VAL B N   1 
ATOM   11145 C CA  . VAL B 1 689 ? 103.345 138.739 163.418 1.00 183.71 ? 709 VAL B CA  1 
ATOM   11146 C C   . VAL B 1 689 ? 103.506 139.875 162.406 1.00 186.43 ? 709 VAL B C   1 
ATOM   11147 O O   . VAL B 1 689 ? 103.180 139.698 161.237 1.00 185.99 ? 709 VAL B O   1 
ATOM   11148 C CB  . VAL B 1 689 ? 101.977 138.778 164.134 1.00 185.62 ? 709 VAL B CB  1 
ATOM   11149 C CG1 . VAL B 1 689 ? 100.824 139.075 163.186 1.00 187.39 ? 709 VAL B CG1 1 
ATOM   11150 C CG2 . VAL B 1 689 ? 101.709 137.486 164.893 1.00 185.01 ? 709 VAL B CG2 1 
ATOM   11151 N N   . ALA B 1 690 ? 104.007 141.034 162.850 1.00 188.38 ? 710 ALA B N   1 
ATOM   11152 C CA  . ALA B 1 690 ? 104.266 142.151 161.951 1.00 189.15 ? 710 ALA B CA  1 
ATOM   11153 C C   . ALA B 1 690 ? 105.306 141.757 160.902 1.00 191.99 ? 710 ALA B C   1 
ATOM   11154 O O   . ALA B 1 690 ? 105.125 142.036 159.715 1.00 191.53 ? 710 ALA B O   1 
ATOM   11155 C CB  . ALA B 1 690 ? 104.707 143.365 162.734 1.00 187.47 ? 710 ALA B CB  1 
ATOM   11156 N N   . LEU B 1 691 ? 106.390 141.106 161.347 1.00 194.42 ? 711 LEU B N   1 
ATOM   11157 C CA  . LEU B 1 691 ? 107.433 140.635 160.446 1.00 196.35 ? 711 LEU B CA  1 
ATOM   11158 C C   . LEU B 1 691 ? 106.867 139.563 159.511 1.00 192.77 ? 711 LEU B C   1 
ATOM   11159 O O   . LEU B 1 691 ? 107.215 139.515 158.336 1.00 190.56 ? 711 LEU B O   1 
ATOM   11160 C CB  . LEU B 1 691 ? 108.599 140.084 161.273 1.00 201.66 ? 711 LEU B CB  1 
ATOM   11161 C CG  . LEU B 1 691 ? 109.374 141.111 162.099 1.00 204.47 ? 711 LEU B CG  1 
ATOM   11162 C CD1 . LEU B 1 691 ? 110.023 140.443 163.302 1.00 204.84 ? 711 LEU B CD1 1 
ATOM   11163 C CD2 . LEU B 1 691 ? 110.424 141.818 161.251 1.00 204.20 ? 711 LEU B CD2 1 
ATOM   11164 N N   . PHE B 1 692 ? 105.993 138.707 160.051 1.00 190.53 ? 712 PHE B N   1 
ATOM   11165 C CA  . PHE B 1 692 ? 105.345 137.654 159.286 1.00 190.50 ? 712 PHE B CA  1 
ATOM   11166 C C   . PHE B 1 692 ? 104.550 138.259 158.129 1.00 194.95 ? 712 PHE B C   1 
ATOM   11167 O O   . PHE B 1 692 ? 104.597 137.754 157.011 1.00 193.24 ? 712 PHE B O   1 
ATOM   11168 C CB  . PHE B 1 692 ? 104.415 136.835 160.187 1.00 187.62 ? 712 PHE B CB  1 
ATOM   11169 C CG  . PHE B 1 692 ? 104.314 135.380 159.813 1.00 185.53 ? 712 PHE B CG  1 
ATOM   11170 C CD1 . PHE B 1 692 ? 105.312 134.497 160.192 1.00 184.58 ? 712 PHE B CD1 1 
ATOM   11171 C CD2 . PHE B 1 692 ? 103.240 134.895 159.083 1.00 184.64 ? 712 PHE B CD2 1 
ATOM   11172 C CE1 . PHE B 1 692 ? 105.233 133.152 159.863 1.00 184.73 ? 712 PHE B CE1 1 
ATOM   11173 C CE2 . PHE B 1 692 ? 103.171 133.555 158.740 1.00 184.97 ? 712 PHE B CE2 1 
ATOM   11174 C CZ  . PHE B 1 692 ? 104.158 132.684 159.143 1.00 185.01 ? 712 PHE B CZ  1 
ATOM   11175 N N   . ILE B 1 693 ? 103.808 139.337 158.416 1.00 200.50 ? 713 ILE B N   1 
ATOM   11176 C CA  . ILE B 1 693 ? 102.969 139.995 157.426 1.00 205.69 ? 713 ILE B CA  1 
ATOM   11177 C C   . ILE B 1 693 ? 103.845 140.705 156.395 1.00 205.11 ? 713 ILE B C   1 
ATOM   11178 O O   . ILE B 1 693 ? 103.561 140.627 155.204 1.00 204.04 ? 713 ILE B O   1 
ATOM   11179 C CB  . ILE B 1 693 ? 101.965 140.956 158.101 1.00 209.77 ? 713 ILE B CB  1 
ATOM   11180 C CG1 . ILE B 1 693 ? 100.862 140.193 158.842 1.00 211.91 ? 713 ILE B CG1 1 
ATOM   11181 C CG2 . ILE B 1 693 ? 101.382 141.947 157.102 1.00 209.68 ? 713 ILE B CG2 1 
ATOM   11182 C CD1 . ILE B 1 693 ? 99.944  139.382 157.950 1.00 211.97 ? 713 ILE B CD1 1 
ATOM   11183 N N   . MET B 1 694 ? 104.890 141.404 156.855 1.00 205.39 ? 714 MET B N   1 
ATOM   11184 C CA  . MET B 1 694 ? 105.760 142.160 155.967 1.00 208.32 ? 714 MET B CA  1 
ATOM   11185 C C   . MET B 1 694 ? 106.405 141.236 154.930 1.00 207.48 ? 714 MET B C   1 
ATOM   11186 O O   . MET B 1 694 ? 106.393 141.548 153.739 1.00 206.61 ? 714 MET B O   1 
ATOM   11187 C CB  . MET B 1 694 ? 106.854 142.899 156.750 1.00 211.56 ? 714 MET B CB  1 
ATOM   11188 C CG  . MET B 1 694 ? 107.291 144.211 156.113 1.00 212.78 ? 714 MET B CG  1 
ATOM   11189 S SD  . MET B 1 694 ? 106.189 145.603 156.487 1.00 211.27 ? 714 MET B SD  1 
ATOM   11190 C CE  . MET B 1 694 ? 106.961 146.239 157.974 1.00 208.12 ? 714 MET B CE  1 
ATOM   11191 N N   . GLU B 1 695 ? 107.015 140.134 155.391 1.00 206.77 ? 715 GLU B N   1 
ATOM   11192 C CA  . GLU B 1 695 ? 107.598 139.145 154.488 1.00 207.62 ? 715 GLU B CA  1 
ATOM   11193 C C   . GLU B 1 695 ? 107.078 137.756 154.855 1.00 201.34 ? 715 GLU B C   1 
ATOM   11194 O O   . GLU B 1 695 ? 107.506 137.191 155.858 1.00 200.04 ? 715 GLU B O   1 
ATOM   11195 C CB  . GLU B 1 695 ? 109.131 139.150 154.537 1.00 214.41 ? 715 GLU B CB  1 
ATOM   11196 C CG  . GLU B 1 695 ? 109.776 140.202 153.648 1.00 221.05 ? 715 GLU B CG  1 
ATOM   11197 C CD  . GLU B 1 695 ? 109.523 141.642 154.062 1.00 225.34 ? 715 GLU B CD  1 
ATOM   11198 O OE1 . GLU B 1 695 ? 109.673 141.939 155.263 1.00 226.85 ? 715 GLU B OE1 1 
ATOM   11199 O OE2 . GLU B 1 695 ? 109.184 142.466 153.184 1.00 225.14 ? 715 GLU B OE2 1 
ATOM   11200 N N   . PRO B 1 696 ? 106.109 137.175 154.110 1.00 194.01 ? 716 PRO B N   1 
ATOM   11201 C CA  . PRO B 1 696 ? 105.590 135.850 154.443 1.00 187.97 ? 716 PRO B CA  1 
ATOM   11202 C C   . PRO B 1 696 ? 106.573 134.749 154.054 1.00 179.23 ? 716 PRO B C   1 
ATOM   11203 O O   . PRO B 1 696 ? 107.173 134.807 152.984 1.00 175.54 ? 716 PRO B O   1 
ATOM   11204 C CB  . PRO B 1 696 ? 104.286 135.727 153.636 1.00 190.74 ? 716 PRO B CB  1 
ATOM   11205 C CG  . PRO B 1 696 ? 104.055 137.105 153.033 1.00 193.41 ? 716 PRO B CG  1 
ATOM   11206 C CD  . PRO B 1 696 ? 105.421 137.755 152.947 1.00 194.12 ? 716 PRO B CD  1 
ATOM   11207 N N   . PRO B 1 697 ? 106.738 133.695 154.888 1.00 175.72 ? 717 PRO B N   1 
ATOM   11208 C CA  . PRO B 1 697 ? 107.538 132.529 154.513 1.00 174.19 ? 717 PRO B CA  1 
ATOM   11209 C C   . PRO B 1 697 ? 106.878 131.736 153.385 1.00 169.00 ? 717 PRO B C   1 
ATOM   11210 O O   . PRO B 1 697 ? 105.692 131.422 153.463 1.00 167.59 ? 717 PRO B O   1 
ATOM   11211 C CB  . PRO B 1 697 ? 107.622 131.703 155.811 1.00 176.00 ? 717 PRO B CB  1 
ATOM   11212 C CG  . PRO B 1 697 ? 106.396 132.107 156.598 1.00 175.88 ? 717 PRO B CG  1 
ATOM   11213 C CD  . PRO B 1 697 ? 106.153 133.557 156.232 1.00 176.23 ? 717 PRO B CD  1 
ATOM   11214 N N   . ASP B 1 698 ? 107.666 131.448 152.341 1.00 166.65 ? 718 ASP B N   1 
ATOM   11215 C CA  . ASP B 1 698 ? 107.219 130.699 151.177 1.00 167.76 ? 718 ASP B CA  1 
ATOM   11216 C C   . ASP B 1 698 ? 108.276 129.651 150.823 1.00 166.26 ? 718 ASP B C   1 
ATOM   11217 O O   . ASP B 1 698 ? 109.245 129.467 151.555 1.00 164.79 ? 718 ASP B O   1 
ATOM   11218 C CB  . ASP B 1 698 ? 106.968 131.628 149.982 1.00 171.25 ? 718 ASP B CB  1 
ATOM   11219 C CG  . ASP B 1 698 ? 105.836 132.630 150.131 1.00 175.70 ? 718 ASP B CG  1 
ATOM   11220 O OD1 . ASP B 1 698 ? 105.051 132.512 151.089 1.00 177.01 ? 718 ASP B OD1 1 
ATOM   11221 O OD2 . ASP B 1 698 ? 105.747 133.527 149.272 1.00 177.88 ? 718 ASP B OD2 1 
ATOM   11222 N N   . ILE B 1 699 ? 108.060 128.940 149.716 1.00 165.54 ? 719 ILE B N   1 
ATOM   11223 C CA  . ILE B 1 699 ? 109.084 128.083 149.139 1.00 163.70 ? 719 ILE B CA  1 
ATOM   11224 C C   . ILE B 1 699 ? 110.013 128.956 148.300 1.00 159.63 ? 719 ILE B C   1 
ATOM   11225 O O   . ILE B 1 699 ? 109.563 129.623 147.370 1.00 161.80 ? 719 ILE B O   1 
ATOM   11226 C CB  . ILE B 1 699 ? 108.445 126.939 148.323 1.00 166.57 ? 719 ILE B CB  1 
ATOM   11227 C CG1 . ILE B 1 699 ? 108.014 125.788 149.238 1.00 166.38 ? 719 ILE B CG1 1 
ATOM   11228 C CG2 . ILE B 1 699 ? 109.372 126.464 147.211 1.00 167.61 ? 719 ILE B CG2 1 
ATOM   11229 C CD1 . ILE B 1 699 ? 107.134 124.753 148.574 1.00 166.45 ? 719 ILE B CD1 1 
ATOM   11230 N N   . MET B 1 700 ? 111.306 128.948 148.644 1.00 153.00 ? 720 MET B N   1 
ATOM   11231 C CA  . MET B 1 700 ? 112.286 129.773 147.954 1.00 149.13 ? 720 MET B CA  1 
ATOM   11232 C C   . MET B 1 700 ? 113.512 128.923 147.633 1.00 144.73 ? 720 MET B C   1 
ATOM   11233 O O   . MET B 1 700 ? 113.936 128.099 148.438 1.00 143.98 ? 720 MET B O   1 
ATOM   11234 C CB  . MET B 1 700 ? 112.673 130.989 148.800 1.00 149.32 ? 720 MET B CB  1 
ATOM   11235 C CG  . MET B 1 700 ? 113.690 131.897 148.135 1.00 150.15 ? 720 MET B CG  1 
ATOM   11236 S SD  . MET B 1 700 ? 115.412 131.552 148.563 1.00 152.31 ? 720 MET B SD  1 
ATOM   11237 C CE  . MET B 1 700 ? 115.296 131.313 150.336 1.00 152.60 ? 720 MET B CE  1 
ATOM   11238 N N   . HIS B 1 701 ? 114.036 129.103 146.416 1.00 140.04 ? 721 HIS B N   1 
ATOM   11239 C CA  . HIS B 1 701 ? 115.140 128.305 145.910 1.00 136.82 ? 721 HIS B CA  1 
ATOM   11240 C C   . HIS B 1 701 ? 116.411 129.146 145.920 1.00 131.87 ? 721 HIS B C   1 
ATOM   11241 O O   . HIS B 1 701 ? 116.589 130.010 145.064 1.00 130.04 ? 721 HIS B O   1 
ATOM   11242 C CB  . HIS B 1 701 ? 114.842 127.796 144.494 1.00 137.41 ? 721 HIS B CB  1 
ATOM   11243 C CG  . HIS B 1 701 ? 113.931 126.617 144.447 1.00 136.57 ? 721 HIS B CG  1 
ATOM   11244 N ND1 . HIS B 1 701 ? 112.557 126.690 144.514 1.00 137.13 ? 721 HIS B ND1 1 
ATOM   11245 C CD2 . HIS B 1 701 ? 114.228 125.322 144.310 1.00 135.91 ? 721 HIS B CD2 1 
ATOM   11246 C CE1 . HIS B 1 701 ? 112.051 125.467 144.435 1.00 138.13 ? 721 HIS B CE1 1 
ATOM   11247 N NE2 . HIS B 1 701 ? 113.050 124.619 144.311 1.00 137.00 ? 721 HIS B NE2 1 
ATOM   11248 N N   . ASP B 1 702 ? 117.293 128.874 146.888 1.00 129.86 ? 722 ASP B N   1 
ATOM   11249 C CA  . ASP B 1 702 ? 118.584 129.541 146.954 1.00 130.58 ? 722 ASP B CA  1 
ATOM   11250 C C   . ASP B 1 702 ? 119.504 128.961 145.882 1.00 129.39 ? 722 ASP B C   1 
ATOM   11251 O O   . ASP B 1 702 ? 119.465 127.761 145.616 1.00 129.35 ? 722 ASP B O   1 
ATOM   11252 C CB  . ASP B 1 702 ? 119.204 129.414 148.347 1.00 132.83 ? 722 ASP B CB  1 
ATOM   11253 C CG  . ASP B 1 702 ? 120.479 130.224 148.512 1.00 134.42 ? 722 ASP B CG  1 
ATOM   11254 O OD1 . ASP B 1 702 ? 121.334 130.163 147.602 1.00 134.49 ? 722 ASP B OD1 1 
ATOM   11255 O OD2 . ASP B 1 702 ? 120.610 130.903 149.552 1.00 136.11 ? 722 ASP B OD2 1 
ATOM   11256 N N   . TYR B 1 703 ? 120.329 129.827 145.279 1.00 125.98 ? 723 TYR B N   1 
ATOM   11257 C CA  . TYR B 1 703 ? 121.314 129.420 144.292 1.00 122.82 ? 723 TYR B CA  1 
ATOM   11258 C C   . TYR B 1 703 ? 122.690 129.918 144.717 1.00 124.98 ? 723 TYR B C   1 
ATOM   11259 O O   . TYR B 1 703 ? 123.139 130.967 144.259 1.00 124.12 ? 723 TYR B O   1 
ATOM   11260 C CB  . TYR B 1 703 ? 120.931 129.964 142.914 1.00 120.10 ? 723 TYR B CB  1 
ATOM   11261 C CG  . TYR B 1 703 ? 119.564 129.542 142.440 1.00 118.39 ? 723 TYR B CG  1 
ATOM   11262 C CD1 . TYR B 1 703 ? 119.225 128.203 142.339 1.00 117.24 ? 723 TYR B CD1 1 
ATOM   11263 C CD2 . TYR B 1 703 ? 118.607 130.480 142.093 1.00 118.70 ? 723 TYR B CD2 1 
ATOM   11264 C CE1 . TYR B 1 703 ? 117.973 127.803 141.899 1.00 117.22 ? 723 TYR B CE1 1 
ATOM   11265 C CE2 . TYR B 1 703 ? 117.351 130.099 141.646 1.00 118.56 ? 723 TYR B CE2 1 
ATOM   11266 C CZ  . TYR B 1 703 ? 117.035 128.756 141.542 1.00 118.25 ? 723 TYR B CZ  1 
ATOM   11267 O OH  . TYR B 1 703 ? 115.789 128.371 141.107 1.00 118.59 ? 723 TYR B OH  1 
ATOM   11268 N N   . PRO B 1 704 ? 123.415 129.188 145.597 1.00 130.52 ? 724 PRO B N   1 
ATOM   11269 C CA  . PRO B 1 704 ? 124.726 129.640 146.063 1.00 133.95 ? 724 PRO B CA  1 
ATOM   11270 C C   . PRO B 1 704 ? 125.757 129.630 144.934 1.00 136.23 ? 724 PRO B C   1 
ATOM   11271 O O   . PRO B 1 704 ? 126.515 130.583 144.774 1.00 138.47 ? 724 PRO B O   1 
ATOM   11272 C CB  . PRO B 1 704 ? 125.103 128.653 147.179 1.00 134.37 ? 724 PRO B CB  1 
ATOM   11273 C CG  . PRO B 1 704 ? 123.831 127.874 147.463 1.00 133.98 ? 724 PRO B CG  1 
ATOM   11274 C CD  . PRO B 1 704 ? 123.047 127.883 146.167 1.00 132.26 ? 724 PRO B CD  1 
ATOM   11275 N N   . SER B 1 705 ? 125.764 128.543 144.156 1.00 135.48 ? 725 SER B N   1 
ATOM   11276 C CA  . SER B 1 705 ? 126.626 128.405 142.995 1.00 135.00 ? 725 SER B CA  1 
ATOM   11277 C C   . SER B 1 705 ? 125.785 127.964 141.801 1.00 132.54 ? 725 SER B C   1 
ATOM   11278 O O   . SER B 1 705 ? 124.579 127.763 141.917 1.00 132.51 ? 725 SER B O   1 
ATOM   11279 C CB  . SER B 1 705 ? 127.749 127.435 143.272 1.00 136.28 ? 725 SER B CB  1 
ATOM   11280 O OG  . SER B 1 705 ? 127.237 126.149 143.587 1.00 136.44 ? 725 SER B OG  1 
ATOM   11281 N N   . ILE B 1 706 ? 126.432 127.810 140.643 1.00 129.31 ? 726 ILE B N   1 
ATOM   11282 C CA  . ILE B 1 706 ? 125.736 127.436 139.423 1.00 127.51 ? 726 ILE B CA  1 
ATOM   11283 C C   . ILE B 1 706 ? 125.392 125.946 139.448 1.00 125.44 ? 726 ILE B C   1 
ATOM   11284 O O   . ILE B 1 706 ? 124.545 125.510 138.677 1.00 124.78 ? 726 ILE B O   1 
ATOM   11285 C CB  . ILE B 1 706 ? 126.582 127.805 138.187 1.00 127.87 ? 726 ILE B CB  1 
ATOM   11286 C CG1 . ILE B 1 706 ? 125.738 127.930 136.915 1.00 127.75 ? 726 ILE B CG1 1 
ATOM   11287 C CG2 . ILE B 1 706 ? 127.731 126.825 138.005 1.00 128.53 ? 726 ILE B CG2 1 
ATOM   11288 C CD1 . ILE B 1 706 ? 124.834 129.144 136.880 1.00 128.34 ? 726 ILE B CD1 1 
ATOM   11289 N N   . ARG B 1 707 ? 126.061 125.163 140.304 1.00 126.33 ? 727 ARG B N   1 
ATOM   11290 C CA  . ARG B 1 707 ? 125.964 123.711 140.248 1.00 130.00 ? 727 ARG B CA  1 
ATOM   11291 C C   . ARG B 1 707 ? 124.896 123.200 141.212 1.00 132.57 ? 727 ARG B C   1 
ATOM   11292 O O   . ARG B 1 707 ? 123.958 122.529 140.789 1.00 133.99 ? 727 ARG B O   1 
ATOM   11293 C CB  . ARG B 1 707 ? 127.326 123.076 140.542 1.00 133.74 ? 727 ARG B CB  1 
ATOM   11294 C CG  . ARG B 1 707 ? 128.319 123.210 139.397 1.00 138.70 ? 727 ARG B CG  1 
ATOM   11295 C CD  . ARG B 1 707 ? 129.697 122.684 139.747 1.00 144.45 ? 727 ARG B CD  1 
ATOM   11296 N NE  . ARG B 1 707 ? 130.670 122.979 138.703 1.00 150.19 ? 727 ARG B NE  1 
ATOM   11297 C CZ  . ARG B 1 707 ? 131.962 122.662 138.752 1.00 156.28 ? 727 ARG B CZ  1 
ATOM   11298 N NH1 . ARG B 1 707 ? 132.456 122.016 139.796 1.00 157.71 ? 727 ARG B NH1 1 
ATOM   11299 N NH2 . ARG B 1 707 ? 132.760 122.994 137.750 1.00 157.73 ? 727 ARG B NH2 1 
ATOM   11300 N N   . GLU B 1 708 ? 125.056 123.502 142.505 1.00 134.32 ? 728 GLU B N   1 
ATOM   11301 C CA  . GLU B 1 708 ? 124.185 122.956 143.536 1.00 134.95 ? 728 GLU B CA  1 
ATOM   11302 C C   . GLU B 1 708 ? 123.081 123.960 143.864 1.00 132.85 ? 728 GLU B C   1 
ATOM   11303 O O   . GLU B 1 708 ? 123.304 125.168 143.855 1.00 131.34 ? 728 GLU B O   1 
ATOM   11304 C CB  . GLU B 1 708 ? 124.993 122.533 144.771 1.00 138.49 ? 728 GLU B CB  1 
ATOM   11305 C CG  . GLU B 1 708 ? 125.965 123.584 145.301 1.00 142.16 ? 728 GLU B CG  1 
ATOM   11306 C CD  . GLU B 1 708 ? 125.340 124.746 146.058 1.00 144.28 ? 728 GLU B CD  1 
ATOM   11307 O OE1 . GLU B 1 708 ? 124.192 124.597 146.530 1.00 144.62 ? 728 GLU B OE1 1 
ATOM   11308 O OE2 . GLU B 1 708 ? 126.000 125.805 146.163 1.00 143.28 ? 728 GLU B OE2 1 
ATOM   11309 N N   . VAL B 1 709 ? 121.882 123.436 144.150 1.00 134.33 ? 729 VAL B N   1 
ATOM   11310 C CA  . VAL B 1 709 ? 120.753 124.243 144.589 1.00 136.89 ? 729 VAL B CA  1 
ATOM   11311 C C   . VAL B 1 709 ? 120.089 123.540 145.769 1.00 140.68 ? 729 VAL B C   1 
ATOM   11312 O O   . VAL B 1 709 ? 120.117 122.315 145.881 1.00 142.65 ? 729 VAL B O   1 
ATOM   11313 C CB  . VAL B 1 709 ? 119.727 124.516 143.467 1.00 134.88 ? 729 VAL B CB  1 
ATOM   11314 C CG1 . VAL B 1 709 ? 120.408 124.959 142.182 1.00 134.82 ? 729 VAL B CG1 1 
ATOM   11315 C CG2 . VAL B 1 709 ? 118.815 123.325 143.200 1.00 134.08 ? 729 VAL B CG2 1 
ATOM   11316 N N   . TYR B 1 710 ? 119.452 124.337 146.633 1.00 138.83 ? 730 TYR B N   1 
ATOM   11317 C CA  . TYR B 1 710 ? 118.752 123.829 147.804 1.00 135.90 ? 730 TYR B CA  1 
ATOM   11318 C C   . TYR B 1 710 ? 117.350 124.432 147.843 1.00 134.27 ? 730 TYR B C   1 
ATOM   11319 O O   . TYR B 1 710 ? 117.047 125.368 147.105 1.00 132.21 ? 730 TYR B O   1 
ATOM   11320 C CB  . TYR B 1 710 ? 119.500 124.172 149.098 1.00 135.74 ? 730 TYR B CB  1 
ATOM   11321 C CG  . TYR B 1 710 ? 120.964 123.813 149.114 1.00 136.09 ? 730 TYR B CG  1 
ATOM   11322 C CD1 . TYR B 1 710 ? 121.383 122.534 148.788 1.00 137.07 ? 730 TYR B CD1 1 
ATOM   11323 C CD2 . TYR B 1 710 ? 121.931 124.741 149.469 1.00 135.77 ? 730 TYR B CD2 1 
ATOM   11324 C CE1 . TYR B 1 710 ? 122.726 122.190 148.786 1.00 138.33 ? 730 TYR B CE1 1 
ATOM   11325 C CE2 . TYR B 1 710 ? 123.277 124.412 149.476 1.00 137.04 ? 730 TYR B CE2 1 
ATOM   11326 C CZ  . TYR B 1 710 ? 123.676 123.130 149.144 1.00 138.30 ? 730 TYR B CZ  1 
ATOM   11327 O OH  . TYR B 1 710 ? 125.012 122.814 149.144 1.00 138.24 ? 730 TYR B OH  1 
ATOM   11328 N N   . LEU B 1 711 ? 116.498 123.885 148.718 1.00 133.82 ? 731 LEU B N   1 
ATOM   11329 C CA  . LEU B 1 711 ? 115.221 124.500 149.039 1.00 134.43 ? 731 LEU B CA  1 
ATOM   11330 C C   . LEU B 1 711 ? 115.224 124.913 150.509 1.00 133.93 ? 731 LEU B C   1 
ATOM   11331 O O   . LEU B 1 711 ? 115.455 124.081 151.386 1.00 133.20 ? 731 LEU B O   1 
ATOM   11332 C CB  . LEU B 1 711 ? 114.090 123.516 148.719 1.00 134.73 ? 731 LEU B CB  1 
ATOM   11333 C CG  . LEU B 1 711 ? 112.700 123.899 149.226 1.00 135.32 ? 731 LEU B CG  1 
ATOM   11334 C CD1 . LEU B 1 711 ? 112.330 125.312 148.803 1.00 134.25 ? 731 LEU B CD1 1 
ATOM   11335 C CD2 . LEU B 1 711 ? 111.658 122.910 148.727 1.00 135.97 ? 731 LEU B CD2 1 
ATOM   11336 N N   . ILE B 1 712 ? 114.987 126.208 150.753 1.00 135.76 ? 732 ILE B N   1 
ATOM   11337 C CA  . ILE B 1 712 ? 114.957 126.761 152.098 1.00 139.64 ? 732 ILE B CA  1 
ATOM   11338 C C   . ILE B 1 712 ? 113.858 127.813 152.182 1.00 142.58 ? 732 ILE B C   1 
ATOM   11339 O O   . ILE B 1 712 ? 113.540 128.476 151.195 1.00 144.47 ? 732 ILE B O   1 
ATOM   11340 C CB  . ILE B 1 712 ? 116.320 127.364 152.497 1.00 142.87 ? 732 ILE B CB  1 
ATOM   11341 C CG1 . ILE B 1 712 ? 116.890 128.255 151.391 1.00 142.75 ? 732 ILE B CG1 1 
ATOM   11342 C CG2 . ILE B 1 712 ? 117.305 126.274 152.895 1.00 144.24 ? 732 ILE B CG2 1 
ATOM   11343 C CD1 . ILE B 1 712 ? 117.960 129.211 151.869 1.00 143.76 ? 732 ILE B CD1 1 
ATOM   11344 N N   . CYS B 1 713 ? 113.314 127.996 153.387 1.00 144.39 ? 733 CYS B N   1 
ATOM   11345 C CA  . CYS B 1 713 ? 112.305 129.016 153.623 1.00 146.26 ? 733 CYS B CA  1 
ATOM   11346 C C   . CYS B 1 713 ? 112.946 130.397 153.501 1.00 142.90 ? 733 CYS B C   1 
ATOM   11347 O O   . CYS B 1 713 ? 114.094 130.585 153.896 1.00 140.00 ? 733 CYS B O   1 
ATOM   11348 C CB  . CYS B 1 713 ? 111.673 128.857 155.001 1.00 151.27 ? 733 CYS B CB  1 
ATOM   11349 S SG  . CYS B 1 713 ? 111.312 127.142 155.471 1.00 158.89 ? 733 CYS B SG  1 
ATOM   11350 N N   . ASN B 1 714 ? 112.193 131.356 152.948 1.00 145.08 ? 734 ASN B N   1 
ATOM   11351 C CA  . ASN B 1 714 ? 112.701 132.692 152.676 1.00 147.93 ? 734 ASN B CA  1 
ATOM   11352 C C   . ASN B 1 714 ? 112.492 133.579 153.901 1.00 147.97 ? 734 ASN B C   1 
ATOM   11353 O O   . ASN B 1 714 ? 111.833 134.615 153.823 1.00 147.92 ? 734 ASN B O   1 
ATOM   11354 C CB  . ASN B 1 714 ? 112.060 133.324 151.435 1.00 149.86 ? 734 ASN B CB  1 
ATOM   11355 C CG  . ASN B 1 714 ? 110.553 133.171 151.402 1.00 152.00 ? 734 ASN B CG  1 
ATOM   11356 O OD1 . ASN B 1 714 ? 110.056 132.076 151.151 1.00 150.26 ? 734 ASN B OD1 1 
ATOM   11357 N ND2 . ASN B 1 714 ? 109.818 134.244 151.652 1.00 153.50 ? 734 ASN B ND2 1 
ATOM   11358 N N   . THR B 1 715 ? 113.080 133.175 155.031 1.00 150.18 ? 735 THR B N   1 
ATOM   11359 C CA  . THR B 1 715 ? 113.098 134.015 156.217 1.00 152.47 ? 735 THR B CA  1 
ATOM   11360 C C   . THR B 1 715 ? 114.215 135.042 156.051 1.00 151.12 ? 735 THR B C   1 
ATOM   11361 O O   . THR B 1 715 ? 115.390 134.689 156.104 1.00 150.58 ? 735 THR B O   1 
ATOM   11362 C CB  . THR B 1 715 ? 113.264 133.191 157.500 1.00 155.97 ? 735 THR B CB  1 
ATOM   11363 O OG1 . THR B 1 715 ? 112.399 132.056 157.435 1.00 157.15 ? 735 THR B OG1 1 
ATOM   11364 C CG2 . THR B 1 715 ? 112.966 134.001 158.744 1.00 156.06 ? 735 THR B CG2 1 
ATOM   11365 N N   . THR B 1 716 ? 113.823 136.303 155.838 1.00 151.71 ? 736 THR B N   1 
ATOM   11366 C CA  . THR B 1 716 ? 114.749 137.372 155.507 1.00 153.15 ? 736 THR B CA  1 
ATOM   11367 C C   . THR B 1 716 ? 115.697 137.617 156.681 1.00 156.44 ? 736 THR B C   1 
ATOM   11368 O O   . THR B 1 716 ? 115.408 137.226 157.811 1.00 157.00 ? 736 THR B O   1 
ATOM   11369 C CB  . THR B 1 716 ? 113.980 138.645 155.120 1.00 152.78 ? 736 THR B CB  1 
ATOM   11370 O OG1 . THR B 1 716 ? 112.947 138.294 154.196 1.00 151.94 ? 736 THR B OG1 1 
ATOM   11371 C CG2 . THR B 1 716 ? 114.855 139.717 154.508 1.00 153.78 ? 736 THR B CG2 1 
ATOM   11372 N N   . ASN B 1 717 ? 116.836 138.258 156.385 1.00 159.62 ? 737 ASN B N   1 
ATOM   11373 C CA  . ASN B 1 717 ? 117.833 138.585 157.391 1.00 163.42 ? 737 ASN B CA  1 
ATOM   11374 C C   . ASN B 1 717 ? 117.197 139.422 158.500 1.00 164.30 ? 737 ASN B C   1 
ATOM   11375 O O   . ASN B 1 717 ? 117.472 139.204 159.674 1.00 163.27 ? 737 ASN B O   1 
ATOM   11376 C CB  . ASN B 1 717 ? 119.049 139.290 156.779 1.00 165.96 ? 737 ASN B CB  1 
ATOM   11377 C CG  . ASN B 1 717 ? 118.705 140.599 156.099 1.00 168.81 ? 737 ASN B CG  1 
ATOM   11378 O OD1 . ASN B 1 717 ? 117.905 141.373 156.622 1.00 168.36 ? 737 ASN B OD1 1 
ATOM   11379 N ND2 . ASN B 1 717 ? 119.286 140.854 154.936 1.00 170.11 ? 737 ASN B ND2 1 
ATOM   11380 N N   . LEU B 1 718 ? 116.356 140.393 158.124 1.00 164.40 ? 738 LEU B N   1 
ATOM   11381 C CA  . LEU B 1 718 ? 115.655 141.202 159.105 1.00 163.49 ? 738 LEU B CA  1 
ATOM   11382 C C   . LEU B 1 718 ? 114.705 140.313 159.910 1.00 158.94 ? 738 LEU B C   1 
ATOM   11383 O O   . LEU B 1 718 ? 114.590 140.467 161.122 1.00 155.49 ? 738 LEU B O   1 
ATOM   11384 C CB  . LEU B 1 718 ? 114.922 142.345 158.398 1.00 166.46 ? 738 LEU B CB  1 
ATOM   11385 C CG  . LEU B 1 718 ? 114.442 143.475 159.307 1.00 169.41 ? 738 LEU B CG  1 
ATOM   11386 C CD1 . LEU B 1 718 ? 115.521 143.874 160.306 1.00 170.04 ? 738 LEU B CD1 1 
ATOM   11387 C CD2 . LEU B 1 718 ? 114.017 144.673 158.479 1.00 169.94 ? 738 LEU B CD2 1 
ATOM   11388 N N   . GLY B 1 719 ? 114.061 139.359 159.228 1.00 156.56 ? 739 GLY B N   1 
ATOM   11389 C CA  . GLY B 1 719 ? 113.109 138.452 159.851 1.00 156.00 ? 739 GLY B CA  1 
ATOM   11390 C C   . GLY B 1 719 ? 113.728 137.592 160.952 1.00 155.59 ? 739 GLY B C   1 
ATOM   11391 O O   . GLY B 1 719 ? 113.039 137.187 161.885 1.00 156.61 ? 739 GLY B O   1 
ATOM   11392 N N   . VAL B 1 720 ? 115.028 137.300 160.832 1.00 152.30 ? 740 VAL B N   1 
ATOM   11393 C CA  . VAL B 1 720 ? 115.716 136.476 161.814 1.00 148.75 ? 740 VAL B CA  1 
ATOM   11394 C C   . VAL B 1 720 ? 116.362 137.363 162.877 1.00 144.95 ? 740 VAL B C   1 
ATOM   11395 O O   . VAL B 1 720 ? 116.438 136.957 164.031 1.00 141.47 ? 740 VAL B O   1 
ATOM   11396 C CB  . VAL B 1 720 ? 116.750 135.535 161.164 1.00 149.11 ? 740 VAL B CB  1 
ATOM   11397 C CG1 . VAL B 1 720 ? 116.126 134.668 160.083 1.00 149.51 ? 740 VAL B CG1 1 
ATOM   11398 C CG2 . VAL B 1 720 ? 117.956 136.282 160.612 1.00 148.58 ? 740 VAL B CG2 1 
ATOM   11399 N N   . VAL B 1 721 ? 116.819 138.567 162.498 1.00 143.41 ? 741 VAL B N   1 
ATOM   11400 C CA  . VAL B 1 721 ? 117.573 139.398 163.424 1.00 141.68 ? 741 VAL B CA  1 
ATOM   11401 C C   . VAL B 1 721 ? 116.624 140.145 164.365 1.00 138.87 ? 741 VAL B C   1 
ATOM   11402 O O   . VAL B 1 721 ? 117.049 140.561 165.439 1.00 137.38 ? 741 VAL B O   1 
ATOM   11403 C CB  . VAL B 1 721 ? 118.518 140.375 162.698 1.00 140.02 ? 741 VAL B CB  1 
ATOM   11404 C CG1 . VAL B 1 721 ? 117.761 141.528 162.066 1.00 140.69 ? 741 VAL B CG1 1 
ATOM   11405 C CG2 . VAL B 1 721 ? 119.607 140.896 163.622 1.00 138.23 ? 741 VAL B CG2 1 
ATOM   11406 N N   . ALA B 1 722 ? 115.358 140.341 163.974 1.00 134.93 ? 742 ALA B N   1 
ATOM   11407 C CA  . ALA B 1 722 ? 114.470 141.168 164.781 1.00 132.12 ? 742 ALA B CA  1 
ATOM   11408 C C   . ALA B 1 722 ? 114.023 140.404 166.030 1.00 128.90 ? 742 ALA B C   1 
ATOM   11409 O O   . ALA B 1 722 ? 114.234 140.882 167.143 1.00 126.67 ? 742 ALA B O   1 
ATOM   11410 C CB  . ALA B 1 722 ? 113.314 141.692 163.961 1.00 133.02 ? 742 ALA B CB  1 
ATOM   11411 N N   . PRO B 1 723 ? 113.390 139.209 165.929 1.00 128.96 ? 743 PRO B N   1 
ATOM   11412 C CA  . PRO B 1 723 ? 113.079 138.413 167.118 1.00 128.69 ? 743 PRO B CA  1 
ATOM   11413 C C   . PRO B 1 723 ? 114.328 138.080 167.929 1.00 129.09 ? 743 PRO B C   1 
ATOM   11414 O O   . PRO B 1 723 ? 114.301 138.107 169.154 1.00 129.85 ? 743 PRO B O   1 
ATOM   11415 C CB  . PRO B 1 723 ? 112.441 137.130 166.565 1.00 130.18 ? 743 PRO B CB  1 
ATOM   11416 C CG  . PRO B 1 723 ? 111.917 137.534 165.207 1.00 131.10 ? 743 PRO B CG  1 
ATOM   11417 C CD  . PRO B 1 723 ? 112.902 138.567 164.699 1.00 130.32 ? 743 PRO B CD  1 
ATOM   11418 N N   . LEU B 1 724 ? 115.425 137.770 167.231 1.00 129.63 ? 744 LEU B N   1 
ATOM   11419 C CA  . LEU B 1 724 ? 116.704 137.491 167.870 1.00 129.99 ? 744 LEU B CA  1 
ATOM   11420 C C   . LEU B 1 724 ? 117.179 138.730 168.628 1.00 130.38 ? 744 LEU B C   1 
ATOM   11421 O O   . LEU B 1 724 ? 117.682 138.621 169.741 1.00 130.09 ? 744 LEU B O   1 
ATOM   11422 C CB  . LEU B 1 724 ? 117.690 137.061 166.778 1.00 130.66 ? 744 LEU B CB  1 
ATOM   11423 C CG  . LEU B 1 724 ? 119.089 136.604 167.190 1.00 132.98 ? 744 LEU B CG  1 
ATOM   11424 C CD1 . LEU B 1 724 ? 119.733 135.865 166.025 1.00 134.48 ? 744 LEU B CD1 1 
ATOM   11425 C CD2 . LEU B 1 724 ? 119.976 137.769 167.611 1.00 134.29 ? 744 LEU B CD2 1 
ATOM   11426 N N   . GLY B 1 725 ? 117.016 139.906 168.014 1.00 129.85 ? 745 GLY B N   1 
ATOM   11427 C CA  . GLY B 1 725 ? 117.378 141.165 168.644 1.00 130.08 ? 745 GLY B CA  1 
ATOM   11428 C C   . GLY B 1 725 ? 116.613 141.387 169.943 1.00 128.37 ? 745 GLY B C   1 
ATOM   11429 O O   . GLY B 1 725 ? 117.211 141.731 170.956 1.00 126.23 ? 745 GLY B O   1 
ATOM   11430 N N   . TYR B 1 726 ? 115.292 141.181 169.905 1.00 128.02 ? 746 TYR B N   1 
ATOM   11431 C CA  . TYR B 1 726 ? 114.456 141.379 171.076 1.00 129.06 ? 746 TYR B CA  1 
ATOM   11432 C C   . TYR B 1 726 ? 114.871 140.390 172.162 1.00 122.14 ? 746 TYR B C   1 
ATOM   11433 O O   . TYR B 1 726 ? 115.061 140.789 173.306 1.00 121.70 ? 746 TYR B O   1 
ATOM   11434 C CB  . TYR B 1 726 ? 112.969 141.271 170.720 1.00 135.30 ? 746 TYR B CB  1 
ATOM   11435 C CG  . TYR B 1 726 ? 112.011 141.290 171.890 1.00 142.72 ? 746 TYR B CG  1 
ATOM   11436 C CD1 . TYR B 1 726 ? 112.391 141.727 173.153 1.00 146.04 ? 746 TYR B CD1 1 
ATOM   11437 C CD2 . TYR B 1 726 ? 110.719 140.818 171.743 1.00 146.02 ? 746 TYR B CD2 1 
ATOM   11438 C CE1 . TYR B 1 726 ? 111.516 141.710 174.226 1.00 148.00 ? 746 TYR B CE1 1 
ATOM   11439 C CE2 . TYR B 1 726 ? 109.825 140.807 172.802 1.00 147.83 ? 746 TYR B CE2 1 
ATOM   11440 C CZ  . TYR B 1 726 ? 110.223 141.251 174.049 1.00 149.19 ? 746 TYR B CZ  1 
ATOM   11441 O OH  . TYR B 1 726 ? 109.325 141.219 175.089 1.00 149.93 ? 746 TYR B OH  1 
ATOM   11442 N N   . ASN B 1 727 ? 115.037 139.116 171.799 1.00 117.51 ? 747 ASN B N   1 
ATOM   11443 C CA  . ASN B 1 727 ? 115.406 138.097 172.767 1.00 115.31 ? 747 ASN B CA  1 
ATOM   11444 C C   . ASN B 1 727 ? 116.770 138.424 173.375 1.00 118.69 ? 747 ASN B C   1 
ATOM   11445 O O   . ASN B 1 727 ? 116.996 138.162 174.553 1.00 117.84 ? 747 ASN B O   1 
ATOM   11446 C CB  . ASN B 1 727 ? 115.387 136.692 172.159 1.00 111.12 ? 747 ASN B CB  1 
ATOM   11447 C CG  . ASN B 1 727 ? 114.017 136.300 171.651 1.00 107.79 ? 747 ASN B CG  1 
ATOM   11448 O OD1 . ASN B 1 727 ? 113.007 136.734 172.200 1.00 108.51 ? 747 ASN B OD1 1 
ATOM   11449 N ND2 . ASN B 1 727 ? 113.975 135.512 170.589 1.00 106.23 ? 747 ASN B ND2 1 
ATOM   11450 N N   . GLY B 1 728 ? 117.668 139.001 172.566 1.00 122.57 ? 748 GLY B N   1 
ATOM   11451 C CA  . GLY B 1 728 ? 118.957 139.468 173.052 1.00 126.44 ? 748 GLY B CA  1 
ATOM   11452 C C   . GLY B 1 728 ? 118.809 140.556 174.117 1.00 128.40 ? 748 GLY B C   1 
ATOM   11453 O O   . GLY B 1 728 ? 119.482 140.523 175.144 1.00 128.49 ? 748 GLY B O   1 
ATOM   11454 N N   . LEU B 1 729 ? 117.925 141.526 173.857 1.00 127.39 ? 749 LEU B N   1 
ATOM   11455 C CA  . LEU B 1 729 ? 117.665 142.589 174.814 1.00 127.21 ? 749 LEU B CA  1 
ATOM   11456 C C   . LEU B 1 729 ? 117.121 141.979 176.103 1.00 121.56 ? 749 LEU B C   1 
ATOM   11457 O O   . LEU B 1 729 ? 117.509 142.387 177.192 1.00 120.27 ? 749 LEU B O   1 
ATOM   11458 C CB  . LEU B 1 729 ? 116.681 143.603 174.216 1.00 131.40 ? 749 LEU B CB  1 
ATOM   11459 C CG  . LEU B 1 729 ? 117.212 144.461 173.067 1.00 134.67 ? 749 LEU B CG  1 
ATOM   11460 C CD1 . LEU B 1 729 ? 116.141 145.423 172.574 1.00 135.45 ? 749 LEU B CD1 1 
ATOM   11461 C CD2 . LEU B 1 729 ? 118.461 145.229 173.476 1.00 135.48 ? 749 LEU B CD2 1 
ATOM   11462 N N   . LEU B 1 730 ? 116.230 140.990 175.966 1.00 118.22 ? 750 LEU B N   1 
ATOM   11463 C CA  . LEU B 1 730 ? 115.614 140.349 177.118 1.00 117.45 ? 750 LEU B CA  1 
ATOM   11464 C C   . LEU B 1 730 ? 116.678 139.629 177.942 1.00 118.37 ? 750 LEU B C   1 
ATOM   11465 O O   . LEU B 1 730 ? 116.690 139.739 179.166 1.00 118.55 ? 750 LEU B O   1 
ATOM   11466 C CB  . LEU B 1 730 ? 114.512 139.389 176.649 1.00 117.04 ? 750 LEU B CB  1 
ATOM   11467 C CG  . LEU B 1 730 ? 113.088 139.787 177.035 1.00 119.06 ? 750 LEU B CG  1 
ATOM   11468 C CD1 . LEU B 1 730 ? 112.064 138.881 176.367 1.00 119.86 ? 750 LEU B CD1 1 
ATOM   11469 C CD2 . LEU B 1 730 ? 112.925 139.741 178.548 1.00 119.85 ? 750 LEU B CD2 1 
ATOM   11470 N N   . ILE B 1 731 ? 117.574 138.902 177.265 1.00 119.89 ? 751 ILE B N   1 
ATOM   11471 C CA  . ILE B 1 731 ? 118.567 138.104 177.959 1.00 121.46 ? 751 ILE B CA  1 
ATOM   11472 C C   . ILE B 1 731 ? 119.589 139.025 178.619 1.00 123.70 ? 751 ILE B C   1 
ATOM   11473 O O   . ILE B 1 731 ? 120.109 138.705 179.671 1.00 121.88 ? 751 ILE B O   1 
ATOM   11474 C CB  . ILE B 1 731 ? 119.222 137.077 177.009 1.00 120.44 ? 751 ILE B CB  1 
ATOM   11475 C CG1 . ILE B 1 731 ? 119.846 135.913 177.777 1.00 119.58 ? 751 ILE B CG1 1 
ATOM   11476 C CG2 . ILE B 1 731 ? 120.222 137.717 176.057 1.00 121.26 ? 751 ILE B CG2 1 
ATOM   11477 C CD1 . ILE B 1 731 ? 118.833 135.000 178.418 1.00 118.80 ? 751 ILE B CD1 1 
ATOM   11478 N N   . LEU B 1 732 ? 119.987 140.105 177.954 1.00 129.07 ? 752 LEU B N   1 
ATOM   11479 C CA  . LEU B 1 732 ? 121.029 140.910 178.573 1.00 134.78 ? 752 LEU B CA  1 
ATOM   11480 C C   . LEU B 1 732 ? 120.475 141.481 179.879 1.00 137.37 ? 752 LEU B C   1 
ATOM   11481 O O   . LEU B 1 732 ? 121.159 141.483 180.899 1.00 137.32 ? 752 LEU B O   1 
ATOM   11482 C CB  . LEU B 1 732 ? 121.481 142.000 177.605 1.00 138.25 ? 752 LEU B CB  1 
ATOM   11483 C CG  . LEU B 1 732 ? 122.378 141.522 176.464 1.00 140.01 ? 752 LEU B CG  1 
ATOM   11484 C CD1 . LEU B 1 732 ? 122.263 142.444 175.259 1.00 140.71 ? 752 LEU B CD1 1 
ATOM   11485 C CD2 . LEU B 1 732 ? 123.827 141.419 176.920 1.00 140.55 ? 752 LEU B CD2 1 
ATOM   11486 N N   . ALA B 1 733 ? 119.212 141.915 179.842 1.00 139.97 ? 753 ALA B N   1 
ATOM   11487 C CA  . ALA B 1 733 ? 118.618 142.542 181.012 1.00 142.16 ? 753 ALA B CA  1 
ATOM   11488 C C   . ALA B 1 733 ? 118.383 141.475 182.068 1.00 140.82 ? 753 ALA B C   1 
ATOM   11489 O O   . ALA B 1 733 ? 118.648 141.707 183.249 1.00 141.29 ? 753 ALA B O   1 
ATOM   11490 C CB  . ALA B 1 733 ? 117.339 143.253 180.654 1.00 143.92 ? 753 ALA B CB  1 
ATOM   11491 N N   . CYS B 1 734 ? 117.919 140.298 181.636 1.00 140.75 ? 754 CYS B N   1 
ATOM   11492 C CA  . CYS B 1 734 ? 117.767 139.201 182.580 1.00 145.38 ? 754 CYS B CA  1 
ATOM   11493 C C   . CYS B 1 734 ? 119.089 138.965 183.316 1.00 152.12 ? 754 CYS B C   1 
ATOM   11494 O O   . CYS B 1 734 ? 119.063 138.561 184.482 1.00 152.83 ? 754 CYS B O   1 
ATOM   11495 C CB  . CYS B 1 734 ? 117.300 137.923 181.899 1.00 145.44 ? 754 CYS B CB  1 
ATOM   11496 S SG  . CYS B 1 734 ? 116.322 136.867 183.000 1.00 145.11 ? 754 CYS B SG  1 
ATOM   11497 N N   . THR B 1 735 ? 120.235 139.250 182.659 1.00 159.99 ? 755 THR B N   1 
ATOM   11498 C CA  . THR B 1 735 ? 121.517 139.162 183.363 1.00 167.52 ? 755 THR B CA  1 
ATOM   11499 C C   . THR B 1 735 ? 121.708 140.396 184.238 1.00 173.64 ? 755 THR B C   1 
ATOM   11500 O O   . THR B 1 735 ? 122.020 140.230 185.419 1.00 173.67 ? 755 THR B O   1 
ATOM   11501 C CB  . THR B 1 735 ? 122.724 138.858 182.454 1.00 170.15 ? 755 THR B CB  1 
ATOM   11502 O OG1 . THR B 1 735 ? 123.443 137.786 183.068 1.00 169.25 ? 755 THR B OG1 1 
ATOM   11503 C CG2 . THR B 1 735 ? 123.683 140.011 182.228 1.00 172.20 ? 755 THR B CG2 1 
ATOM   11504 N N   . PHE B 1 736 ? 121.543 141.616 183.712 1.00 178.16 ? 756 PHE B N   1 
ATOM   11505 C CA  . PHE B 1 736 ? 121.634 142.751 184.612 1.00 182.53 ? 756 PHE B CA  1 
ATOM   11506 C C   . PHE B 1 736 ? 120.984 142.367 185.945 1.00 179.21 ? 756 PHE B C   1 
ATOM   11507 O O   . PHE B 1 736 ? 121.544 142.625 187.007 1.00 178.41 ? 756 PHE B O   1 
ATOM   11508 C CB  . PHE B 1 736 ? 120.992 144.003 184.017 1.00 190.12 ? 756 PHE B CB  1 
ATOM   11509 C CG  . PHE B 1 736 ? 121.285 145.297 184.738 1.00 197.80 ? 756 PHE B CG  1 
ATOM   11510 C CD1 . PHE B 1 736 ? 122.261 145.383 185.724 1.00 200.77 ? 756 PHE B CD1 1 
ATOM   11511 C CD2 . PHE B 1 736 ? 120.573 146.445 184.422 1.00 200.89 ? 756 PHE B CD2 1 
ATOM   11512 C CE1 . PHE B 1 736 ? 122.515 146.583 186.370 1.00 202.52 ? 756 PHE B CE1 1 
ATOM   11513 C CE2 . PHE B 1 736 ? 120.827 147.644 185.071 1.00 202.19 ? 756 PHE B CE2 1 
ATOM   11514 C CZ  . PHE B 1 736 ? 121.798 147.711 186.044 1.00 202.66 ? 756 PHE B CZ  1 
ATOM   11515 N N   . TYR B 1 737 ? 119.804 141.737 185.883 1.00 177.79 ? 757 TYR B N   1 
ATOM   11516 C CA  . TYR B 1 737 ? 119.072 141.378 187.089 1.00 178.67 ? 757 TYR B CA  1 
ATOM   11517 C C   . TYR B 1 737 ? 119.782 140.250 187.839 1.00 177.08 ? 757 TYR B C   1 
ATOM   11518 O O   . TYR B 1 737 ? 119.812 140.258 189.067 1.00 176.70 ? 757 TYR B O   1 
ATOM   11519 C CB  . TYR B 1 737 ? 117.616 141.029 186.767 1.00 181.77 ? 757 TYR B CB  1 
ATOM   11520 C CG  . TYR B 1 737 ? 116.615 142.106 187.111 1.00 187.32 ? 757 TYR B CG  1 
ATOM   11521 C CD1 . TYR B 1 737 ? 116.498 143.254 186.343 1.00 191.71 ? 757 TYR B CD1 1 
ATOM   11522 C CD2 . TYR B 1 737 ? 115.797 141.990 188.226 1.00 189.79 ? 757 TYR B CD2 1 
ATOM   11523 C CE1 . TYR B 1 737 ? 115.584 144.248 186.656 1.00 193.78 ? 757 TYR B CE1 1 
ATOM   11524 C CE2 . TYR B 1 737 ? 114.880 142.976 188.555 1.00 193.51 ? 757 TYR B CE2 1 
ATOM   11525 C CZ  . TYR B 1 737 ? 114.776 144.113 187.771 1.00 195.09 ? 757 TYR B CZ  1 
ATOM   11526 O OH  . TYR B 1 737 ? 113.870 145.097 188.089 1.00 192.08 ? 757 TYR B OH  1 
ATOM   11527 N N   . ALA B 1 738 ? 120.327 139.277 187.102 1.00 176.63 ? 758 ALA B N   1 
ATOM   11528 C CA  . ALA B 1 738 ? 121.024 138.152 187.710 1.00 178.77 ? 758 ALA B CA  1 
ATOM   11529 C C   . ALA B 1 738 ? 122.328 138.612 188.359 1.00 183.41 ? 758 ALA B C   1 
ATOM   11530 O O   . ALA B 1 738 ? 122.762 138.032 189.349 1.00 183.65 ? 758 ALA B O   1 
ATOM   11531 C CB  . ALA B 1 738 ? 121.279 137.077 186.683 1.00 178.56 ? 758 ALA B CB  1 
ATOM   11532 N N   . PHE B 1 739 ? 122.962 139.638 187.776 1.00 189.72 ? 759 PHE B N   1 
ATOM   11533 C CA  . PHE B 1 739 ? 124.151 140.278 188.322 1.00 195.51 ? 759 PHE B CA  1 
ATOM   11534 C C   . PHE B 1 739 ? 123.914 140.708 189.770 1.00 193.48 ? 759 PHE B C   1 
ATOM   11535 O O   . PHE B 1 739 ? 124.831 140.670 190.583 1.00 191.53 ? 759 PHE B O   1 
ATOM   11536 C CB  . PHE B 1 739 ? 124.499 141.505 187.472 1.00 202.87 ? 759 PHE B CB  1 
ATOM   11537 C CG  . PHE B 1 739 ? 125.884 142.065 187.672 1.00 212.85 ? 759 PHE B CG  1 
ATOM   11538 C CD1 . PHE B 1 739 ? 126.977 141.437 187.097 1.00 218.21 ? 759 PHE B CD1 1 
ATOM   11539 C CD2 . PHE B 1 739 ? 126.095 143.240 188.379 1.00 217.91 ? 759 PHE B CD2 1 
ATOM   11540 C CE1 . PHE B 1 739 ? 128.255 141.958 187.245 1.00 221.76 ? 759 PHE B CE1 1 
ATOM   11541 C CE2 . PHE B 1 739 ? 127.374 143.754 188.537 1.00 220.06 ? 759 PHE B CE2 1 
ATOM   11542 C CZ  . PHE B 1 739 ? 128.451 143.113 187.968 1.00 221.58 ? 759 PHE B CZ  1 
ATOM   11543 N N   . LYS B 1 740 ? 122.672 141.101 190.075 1.00 193.03 ? 760 LYS B N   1 
ATOM   11544 C CA  . LYS B 1 740 ? 122.296 141.586 191.391 1.00 193.28 ? 760 LYS B CA  1 
ATOM   11545 C C   . LYS B 1 740 ? 122.100 140.413 192.351 1.00 188.80 ? 760 LYS B C   1 
ATOM   11546 O O   . LYS B 1 740 ? 122.406 140.521 193.536 1.00 187.02 ? 760 LYS B O   1 
ATOM   11547 C CB  . LYS B 1 740 ? 121.010 142.417 191.298 1.00 195.69 ? 760 LYS B CB  1 
ATOM   11548 C CG  . LYS B 1 740 ? 120.988 143.457 190.185 1.00 198.25 ? 760 LYS B CG  1 
ATOM   11549 C CD  . LYS B 1 740 ? 119.701 144.249 190.129 1.00 200.26 ? 760 LYS B CD  1 
ATOM   11550 C CE  . LYS B 1 740 ? 119.511 144.967 188.809 1.00 201.95 ? 760 LYS B CE  1 
ATOM   11551 N NZ  . LYS B 1 740 ? 118.196 145.645 188.736 1.00 202.55 ? 760 LYS B NZ  1 
ATOM   11552 N N   . THR B 1 741 ? 121.597 139.285 191.829 1.00 185.08 ? 761 THR B N   1 
ATOM   11553 C CA  . THR B 1 741 ? 121.030 138.230 192.656 1.00 184.25 ? 761 THR B CA  1 
ATOM   11554 C C   . THR B 1 741 ? 122.059 137.157 193.020 1.00 183.62 ? 761 THR B C   1 
ATOM   11555 O O   . THR B 1 741 ? 121.679 136.146 193.601 1.00 183.70 ? 761 THR B O   1 
ATOM   11556 C CB  . THR B 1 741 ? 119.805 137.603 191.967 1.00 184.12 ? 761 THR B CB  1 
ATOM   11557 O OG1 . THR B 1 741 ? 119.013 136.951 192.962 1.00 183.51 ? 761 THR B OG1 1 
ATOM   11558 C CG2 . THR B 1 741 ? 120.150 136.613 190.874 1.00 183.36 ? 761 THR B CG2 1 
ATOM   11559 N N   . ARG B 1 742 ? 123.341 137.356 192.673 1.00 184.74 ? 762 ARG B N   1 
ATOM   11560 C CA  . ARG B 1 742 ? 124.405 136.396 192.943 1.00 188.72 ? 762 ARG B CA  1 
ATOM   11561 C C   . ARG B 1 742 ? 124.247 135.726 194.307 1.00 193.07 ? 762 ARG B C   1 
ATOM   11562 O O   . ARG B 1 742 ? 124.156 134.504 194.401 1.00 194.33 ? 762 ARG B O   1 
ATOM   11563 C CB  . ARG B 1 742 ? 125.774 137.083 192.935 1.00 189.61 ? 762 ARG B CB  1 
ATOM   11564 C CG  . ARG B 1 742 ? 126.551 136.926 191.637 1.00 190.66 ? 762 ARG B CG  1 
ATOM   11565 C CD  . ARG B 1 742 ? 127.966 137.463 191.775 1.00 191.85 ? 762 ARG B CD  1 
ATOM   11566 N NE  . ARG B 1 742 ? 128.007 138.915 191.922 1.00 191.90 ? 762 ARG B NE  1 
ATOM   11567 C CZ  . ARG B 1 742 ? 127.986 139.788 190.916 1.00 190.00 ? 762 ARG B CZ  1 
ATOM   11568 N NH1 . ARG B 1 742 ? 128.088 139.368 189.667 1.00 189.65 ? 762 ARG B NH1 1 
ATOM   11569 N NH2 . ARG B 1 742 ? 127.893 141.083 191.167 1.00 188.50 ? 762 ARG B NH2 1 
ATOM   11570 N N   . ASN B 1 743 ? 124.231 136.554 195.352 1.00 196.31 ? 763 ASN B N   1 
ATOM   11571 C CA  . ASN B 1 743 ? 124.340 136.093 196.727 1.00 200.42 ? 763 ASN B CA  1 
ATOM   11572 C C   . ASN B 1 743 ? 122.997 136.286 197.423 1.00 202.42 ? 763 ASN B C   1 
ATOM   11573 O O   . ASN B 1 743 ? 122.796 137.267 198.133 1.00 201.07 ? 763 ASN B O   1 
ATOM   11574 C CB  . ASN B 1 743 ? 125.472 136.809 197.466 1.00 201.53 ? 763 ASN B CB  1 
ATOM   11575 C CG  . ASN B 1 743 ? 125.427 138.317 197.328 1.00 202.52 ? 763 ASN B CG  1 
ATOM   11576 O OD1 . ASN B 1 743 ? 124.656 138.852 196.534 1.00 203.57 ? 763 ASN B OD1 1 
ATOM   11577 N ND2 . ASN B 1 743 ? 126.259 139.010 198.087 1.00 202.46 ? 763 ASN B ND2 1 
ATOM   11578 N N   . VAL B 1 744 ? 122.076 135.351 197.175 1.00 205.59 ? 764 VAL B N   1 
ATOM   11579 C CA  . VAL B 1 744 ? 120.785 135.369 197.840 1.00 208.11 ? 764 VAL B CA  1 
ATOM   11580 C C   . VAL B 1 744 ? 120.604 134.061 198.601 1.00 210.41 ? 764 VAL B C   1 
ATOM   11581 O O   . VAL B 1 744 ? 120.443 133.004 197.994 1.00 208.79 ? 764 VAL B O   1 
ATOM   11582 C CB  . VAL B 1 744 ? 119.637 135.592 196.842 1.00 208.05 ? 764 VAL B CB  1 
ATOM   11583 C CG1 . VAL B 1 744 ? 118.279 135.452 197.511 1.00 207.59 ? 764 VAL B CG1 1 
ATOM   11584 C CG2 . VAL B 1 744 ? 119.766 136.934 196.139 1.00 207.25 ? 764 VAL B CG2 1 
ATOM   11585 N N   . PRO B 1 745 ? 120.654 134.081 199.953 1.00 215.72 ? 765 PRO B N   1 
ATOM   11586 C CA  . PRO B 1 745 ? 120.252 132.920 200.742 1.00 217.75 ? 765 PRO B CA  1 
ATOM   11587 C C   . PRO B 1 745 ? 118.734 132.795 200.657 1.00 217.94 ? 765 PRO B C   1 
ATOM   11588 O O   . PRO B 1 745 ? 118.013 133.677 201.121 1.00 217.18 ? 765 PRO B O   1 
ATOM   11589 C CB  . PRO B 1 745 ? 120.732 133.195 202.175 1.00 219.60 ? 765 PRO B CB  1 
ATOM   11590 C CG  . PRO B 1 745 ? 121.431 134.550 202.129 1.00 220.05 ? 765 PRO B CG  1 
ATOM   11591 C CD  . PRO B 1 745 ? 121.124 135.193 200.790 1.00 218.22 ? 765 PRO B CD  1 
ATOM   11592 N N   . ALA B 1 746 ? 118.262 131.698 200.057 1.00 219.00 ? 766 ALA B N   1 
ATOM   11593 C CA  . ALA B 1 746 ? 116.855 131.544 199.727 1.00 220.11 ? 766 ALA B CA  1 
ATOM   11594 C C   . ALA B 1 746 ? 116.479 130.067 199.802 1.00 220.60 ? 766 ALA B C   1 
ATOM   11595 O O   . ALA B 1 746 ? 117.183 129.282 200.433 1.00 220.14 ? 766 ALA B O   1 
ATOM   11596 C CB  . ALA B 1 746 ? 116.593 132.140 198.361 1.00 219.67 ? 766 ALA B CB  1 
ATOM   11597 N N   . ASN B 1 747 ? 115.347 129.713 199.183 1.00 222.20 ? 767 ASN B N   1 
ATOM   11598 C CA  . ASN B 1 747 ? 114.855 128.345 199.157 1.00 225.04 ? 767 ASN B CA  1 
ATOM   11599 C C   . ASN B 1 747 ? 115.781 127.492 198.294 1.00 222.63 ? 767 ASN B C   1 
ATOM   11600 O O   . ASN B 1 747 ? 115.640 127.451 197.072 1.00 219.25 ? 767 ASN B O   1 
ATOM   11601 C CB  . ASN B 1 747 ? 113.410 128.286 198.655 1.00 228.48 ? 767 ASN B CB  1 
ATOM   11602 C CG  . ASN B 1 747 ? 112.412 128.844 199.650 1.00 232.04 ? 767 ASN B CG  1 
ATOM   11603 O OD1 . ASN B 1 747 ? 112.692 128.939 200.844 1.00 233.71 ? 767 ASN B OD1 1 
ATOM   11604 N ND2 . ASN B 1 747 ? 111.229 129.194 199.174 1.00 232.29 ? 767 ASN B ND2 1 
ATOM   11605 N N   . PHE B 1 748 ? 116.732 126.818 198.959 1.00 223.54 ? 768 PHE B N   1 
ATOM   11606 C CA  . PHE B 1 748 ? 117.722 125.970 198.312 1.00 225.31 ? 768 PHE B CA  1 
ATOM   11607 C C   . PHE B 1 748 ? 118.681 126.796 197.454 1.00 217.25 ? 768 PHE B C   1 
ATOM   11608 O O   . PHE B 1 748 ? 119.389 126.224 196.631 1.00 216.72 ? 768 PHE B O   1 
ATOM   11609 C CB  . PHE B 1 748 ? 117.039 124.883 197.473 1.00 232.36 ? 768 PHE B CB  1 
ATOM   11610 C CG  . PHE B 1 748 ? 115.963 124.117 198.199 1.00 240.28 ? 768 PHE B CG  1 
ATOM   11611 C CD1 . PHE B 1 748 ? 116.296 123.187 199.171 1.00 244.64 ? 768 PHE B CD1 1 
ATOM   11612 C CD2 . PHE B 1 748 ? 114.621 124.334 197.924 1.00 244.03 ? 768 PHE B CD2 1 
ATOM   11613 C CE1 . PHE B 1 748 ? 115.309 122.475 199.839 1.00 247.59 ? 768 PHE B CE1 1 
ATOM   11614 C CE2 . PHE B 1 748 ? 113.635 123.628 198.598 1.00 246.83 ? 768 PHE B CE2 1 
ATOM   11615 C CZ  . PHE B 1 748 ? 113.981 122.703 199.556 1.00 248.25 ? 768 PHE B CZ  1 
ATOM   11616 N N   . ASN B 1 749 ? 118.686 128.131 197.628 1.00 208.94 ? 769 ASN B N   1 
ATOM   11617 C CA  . ASN B 1 749 ? 119.579 129.024 196.903 1.00 203.49 ? 769 ASN B CA  1 
ATOM   11618 C C   . ASN B 1 749 ? 119.392 128.848 195.394 1.00 194.84 ? 769 ASN B C   1 
ATOM   11619 O O   . ASN B 1 749 ? 120.311 128.418 194.698 1.00 192.81 ? 769 ASN B O   1 
ATOM   11620 C CB  . ASN B 1 749 ? 121.027 128.815 197.360 1.00 206.78 ? 769 ASN B CB  1 
ATOM   11621 C CG  . ASN B 1 749 ? 122.056 129.505 196.490 1.00 209.31 ? 769 ASN B CG  1 
ATOM   11622 O OD1 . ASN B 1 749 ? 122.925 128.847 195.924 1.00 207.90 ? 769 ASN B OD1 1 
ATOM   11623 N ND2 . ASN B 1 749 ? 121.972 130.821 196.382 1.00 210.25 ? 769 ASN B ND2 1 
ATOM   11624 N N   . GLU B 1 750 ? 118.196 129.187 194.896 1.00 187.39 ? 770 GLU B N   1 
ATOM   11625 C CA  . GLU B 1 750 ? 117.891 129.027 193.482 1.00 181.99 ? 770 GLU B CA  1 
ATOM   11626 C C   . GLU B 1 750 ? 118.647 130.072 192.668 1.00 173.55 ? 770 GLU B C   1 
ATOM   11627 O O   . GLU B 1 750 ? 119.128 129.772 191.577 1.00 170.91 ? 770 GLU B O   1 
ATOM   11628 C CB  . GLU B 1 750 ? 116.391 129.141 193.207 1.00 183.21 ? 770 GLU B CB  1 
ATOM   11629 C CG  . GLU B 1 750 ? 115.597 127.939 193.685 1.00 183.90 ? 770 GLU B CG  1 
ATOM   11630 C CD  . GLU B 1 750 ? 114.258 127.751 192.993 1.00 182.71 ? 770 GLU B CD  1 
ATOM   11631 O OE1 . GLU B 1 750 ? 114.256 127.490 191.776 1.00 180.66 ? 770 GLU B OE1 1 
ATOM   11632 O OE2 . GLU B 1 750 ? 113.223 127.872 193.671 1.00 183.97 ? 770 GLU B OE2 1 
ATOM   11633 N N   . ALA B 1 751 ? 118.767 131.286 193.224 1.00 168.46 ? 771 ALA B N   1 
ATOM   11634 C CA  . ALA B 1 751 ? 119.302 132.435 192.505 1.00 166.78 ? 771 ALA B CA  1 
ATOM   11635 C C   . ALA B 1 751 ? 120.673 132.124 191.904 1.00 165.36 ? 771 ALA B C   1 
ATOM   11636 O O   . ALA B 1 751 ? 120.965 132.528 190.782 1.00 164.70 ? 771 ALA B O   1 
ATOM   11637 C CB  . ALA B 1 751 ? 119.369 133.634 193.421 1.00 168.04 ? 771 ALA B CB  1 
ATOM   11638 N N   . LYS B 1 752 ? 121.517 131.417 192.661 1.00 165.80 ? 772 LYS B N   1 
ATOM   11639 C CA  . LYS B 1 752 ? 122.850 131.056 192.209 1.00 166.41 ? 772 LYS B CA  1 
ATOM   11640 C C   . LYS B 1 752 ? 122.757 130.168 190.969 1.00 164.11 ? 772 LYS B C   1 
ATOM   11641 O O   . LYS B 1 752 ? 123.480 130.379 190.000 1.00 163.13 ? 772 LYS B O   1 
ATOM   11642 C CB  . LYS B 1 752 ? 123.608 130.360 193.344 1.00 168.25 ? 772 LYS B CB  1 
ATOM   11643 C CG  . LYS B 1 752 ? 125.017 129.890 193.005 1.00 168.42 ? 772 LYS B CG  1 
ATOM   11644 C CD  . LYS B 1 752 ? 125.911 129.718 194.216 1.00 169.38 ? 772 LYS B CD  1 
ATOM   11645 C CE  . LYS B 1 752 ? 126.333 131.033 194.840 1.00 169.38 ? 772 LYS B CE  1 
ATOM   11646 N NZ  . LYS B 1 752 ? 127.152 130.823 196.057 1.00 168.96 ? 772 LYS B NZ  1 
ATOM   11647 N N   . TYR B 1 753 ? 121.869 129.168 191.014 1.00 161.56 ? 773 TYR B N   1 
ATOM   11648 C CA  . TYR B 1 753 ? 121.709 128.239 189.909 1.00 161.52 ? 773 TYR B CA  1 
ATOM   11649 C C   . TYR B 1 753 ? 121.171 128.965 188.678 1.00 155.51 ? 773 TYR B C   1 
ATOM   11650 O O   . TYR B 1 753 ? 121.605 128.695 187.557 1.00 156.12 ? 773 TYR B O   1 
ATOM   11651 C CB  . TYR B 1 753 ? 120.815 127.063 190.312 1.00 166.97 ? 773 TYR B CB  1 
ATOM   11652 C CG  . TYR B 1 753 ? 121.562 125.847 190.801 1.00 173.72 ? 773 TYR B CG  1 
ATOM   11653 C CD1 . TYR B 1 753 ? 122.595 125.299 190.054 1.00 177.66 ? 773 TYR B CD1 1 
ATOM   11654 C CD2 . TYR B 1 753 ? 121.225 125.222 191.991 1.00 177.66 ? 773 TYR B CD2 1 
ATOM   11655 C CE1 . TYR B 1 753 ? 123.285 124.177 190.484 1.00 181.60 ? 773 TYR B CE1 1 
ATOM   11656 C CE2 . TYR B 1 753 ? 121.908 124.101 192.438 1.00 180.90 ? 773 TYR B CE2 1 
ATOM   11657 C CZ  . TYR B 1 753 ? 122.940 123.574 191.681 1.00 183.11 ? 773 TYR B CZ  1 
ATOM   11658 O OH  . TYR B 1 753 ? 123.621 122.460 192.112 1.00 183.42 ? 773 TYR B OH  1 
ATOM   11659 N N   . ILE B 1 754 ? 120.236 129.899 188.890 1.00 150.03 ? 774 ILE B N   1 
ATOM   11660 C CA  . ILE B 1 754 ? 119.647 130.614 187.771 1.00 146.82 ? 774 ILE B CA  1 
ATOM   11661 C C   . ILE B 1 754 ? 120.710 131.525 187.160 1.00 138.53 ? 774 ILE B C   1 
ATOM   11662 O O   . ILE B 1 754 ? 120.731 131.701 185.948 1.00 135.01 ? 774 ILE B O   1 
ATOM   11663 C CB  . ILE B 1 754 ? 118.355 131.365 188.158 1.00 151.52 ? 774 ILE B CB  1 
ATOM   11664 C CG1 . ILE B 1 754 ? 118.624 132.722 188.814 1.00 153.36 ? 774 ILE B CG1 1 
ATOM   11665 C CG2 . ILE B 1 754 ? 117.452 130.476 189.006 1.00 153.09 ? 774 ILE B CG2 1 
ATOM   11666 C CD1 . ILE B 1 754 ? 117.403 133.608 188.937 1.00 154.43 ? 774 ILE B CD1 1 
ATOM   11667 N N   . ALA B 1 755 ? 121.599 132.076 187.995 1.00 136.12 ? 775 ALA B N   1 
ATOM   11668 C CA  . ALA B 1 755 ? 122.705 132.892 187.517 1.00 135.72 ? 775 ALA B CA  1 
ATOM   11669 C C   . ALA B 1 755 ? 123.634 132.057 186.642 1.00 133.49 ? 775 ALA B C   1 
ATOM   11670 O O   . ALA B 1 755 ? 124.059 132.522 185.591 1.00 133.08 ? 775 ALA B O   1 
ATOM   11671 C CB  . ALA B 1 755 ? 123.451 133.498 188.683 1.00 137.19 ? 775 ALA B CB  1 
ATOM   11672 N N   . PHE B 1 756 ? 123.952 130.832 187.082 1.00 132.66 ? 776 PHE B N   1 
ATOM   11673 C CA  . PHE B 1 756 ? 124.780 129.934 186.290 1.00 132.80 ? 776 PHE B CA  1 
ATOM   11674 C C   . PHE B 1 756 ? 124.138 129.710 184.923 1.00 127.16 ? 776 PHE B C   1 
ATOM   11675 O O   . PHE B 1 756 ? 124.798 129.859 183.896 1.00 124.21 ? 776 PHE B O   1 
ATOM   11676 C CB  . PHE B 1 756 ? 125.003 128.599 187.005 1.00 137.14 ? 776 PHE B CB  1 
ATOM   11677 C CG  . PHE B 1 756 ? 126.066 128.630 188.073 1.00 143.36 ? 776 PHE B CG  1 
ATOM   11678 C CD1 . PHE B 1 756 ? 127.390 128.889 187.752 1.00 146.99 ? 776 PHE B CD1 1 
ATOM   11679 C CD2 . PHE B 1 756 ? 125.740 128.412 189.402 1.00 146.54 ? 776 PHE B CD2 1 
ATOM   11680 C CE1 . PHE B 1 756 ? 128.367 128.920 188.737 1.00 149.38 ? 776 PHE B CE1 1 
ATOM   11681 C CE2 . PHE B 1 756 ? 126.716 128.444 190.387 1.00 148.83 ? 776 PHE B CE2 1 
ATOM   11682 C CZ  . PHE B 1 756 ? 128.028 128.695 190.052 1.00 149.91 ? 776 PHE B CZ  1 
ATOM   11683 N N   . ALA B 1 757 ? 122.844 129.367 184.929 1.00 123.60 ? 777 ALA B N   1 
ATOM   11684 C CA  . ALA B 1 757 ? 122.112 129.087 183.703 1.00 119.34 ? 777 ALA B CA  1 
ATOM   11685 C C   . ALA B 1 757 ? 122.128 130.307 182.779 1.00 113.48 ? 777 ALA B C   1 
ATOM   11686 O O   . ALA B 1 757 ? 122.277 130.179 181.567 1.00 112.26 ? 777 ALA B O   1 
ATOM   11687 C CB  . ALA B 1 757 ? 120.697 128.671 184.032 1.00 119.37 ? 777 ALA B CB  1 
ATOM   11688 N N   . MET B 1 758 ? 121.965 131.494 183.368 1.00 110.27 ? 778 MET B N   1 
ATOM   11689 C CA  . MET B 1 758 ? 121.847 132.722 182.602 1.00 110.03 ? 778 MET B CA  1 
ATOM   11690 C C   . MET B 1 758 ? 123.181 133.053 181.932 1.00 108.94 ? 778 MET B C   1 
ATOM   11691 O O   . MET B 1 758 ? 123.214 133.434 180.762 1.00 106.56 ? 778 MET B O   1 
ATOM   11692 C CB  . MET B 1 758 ? 121.391 133.864 183.516 1.00 111.87 ? 778 MET B CB  1 
ATOM   11693 C CG  . MET B 1 758 ? 119.935 134.233 183.309 1.00 112.05 ? 778 MET B CG  1 
ATOM   11694 S SD  . MET B 1 758 ? 119.727 135.013 181.699 1.00 110.98 ? 778 MET B SD  1 
ATOM   11695 C CE  . MET B 1 758 ? 121.122 136.137 181.717 1.00 112.03 ? 778 MET B CE  1 
ATOM   11696 N N   . TYR B 1 759 ? 124.279 132.895 182.678 1.00 110.60 ? 779 TYR B N   1 
ATOM   11697 C CA  . TYR B 1 759 ? 125.607 133.126 182.131 1.00 111.77 ? 779 TYR B CA  1 
ATOM   11698 C C   . TYR B 1 759 ? 125.856 132.160 180.977 1.00 109.11 ? 779 TYR B C   1 
ATOM   11699 O O   . TYR B 1 759 ? 126.327 132.571 179.924 1.00 107.68 ? 779 TYR B O   1 
ATOM   11700 C CB  . TYR B 1 759 ? 126.688 132.977 183.208 1.00 114.87 ? 779 TYR B CB  1 
ATOM   11701 C CG  . TYR B 1 759 ? 126.724 134.070 184.248 1.00 117.04 ? 779 TYR B CG  1 
ATOM   11702 C CD1 . TYR B 1 759 ? 126.685 135.405 183.877 1.00 118.20 ? 779 TYR B CD1 1 
ATOM   11703 C CD2 . TYR B 1 759 ? 126.854 133.780 185.600 1.00 117.08 ? 779 TYR B CD2 1 
ATOM   11704 C CE1 . TYR B 1 759 ? 126.727 136.422 184.818 1.00 118.08 ? 779 TYR B CE1 1 
ATOM   11705 C CE2 . TYR B 1 759 ? 126.905 134.785 186.553 1.00 117.39 ? 779 TYR B CE2 1 
ATOM   11706 C CZ  . TYR B 1 759 ? 126.844 136.111 186.162 1.00 117.91 ? 779 TYR B CZ  1 
ATOM   11707 O OH  . TYR B 1 759 ? 126.897 137.111 187.104 1.00 118.26 ? 779 TYR B OH  1 
ATOM   11708 N N   . THR B 1 760 ? 125.527 130.881 181.186 1.00 106.63 ? 780 THR B N   1 
ATOM   11709 C CA  . THR B 1 760 ? 125.782 129.839 180.206 1.00 105.13 ? 780 THR B CA  1 
ATOM   11710 C C   . THR B 1 760 ? 124.995 130.119 178.929 1.00 99.44  ? 780 THR B C   1 
ATOM   11711 O O   . THR B 1 760 ? 125.522 129.926 177.837 1.00 96.01  ? 780 THR B O   1 
ATOM   11712 C CB  . THR B 1 760 ? 125.422 128.455 180.768 1.00 109.58 ? 780 THR B CB  1 
ATOM   11713 O OG1 . THR B 1 760 ? 126.140 128.260 181.988 1.00 111.69 ? 780 THR B OG1 1 
ATOM   11714 C CG2 . THR B 1 760 ? 125.720 127.319 179.812 1.00 111.30 ? 780 THR B CG2 1 
ATOM   11715 N N   . THR B 1 761 ? 123.737 130.561 179.077 1.00 99.32  ? 781 THR B N   1 
ATOM   11716 C CA  . THR B 1 761 ? 122.878 130.768 177.922 1.00 100.18 ? 781 THR B CA  1 
ATOM   11717 C C   . THR B 1 761 ? 123.357 131.986 177.135 1.00 96.07  ? 781 THR B C   1 
ATOM   11718 O O   . THR B 1 761 ? 123.309 131.975 175.908 1.00 95.18  ? 781 THR B O   1 
ATOM   11719 C CB  . THR B 1 761 ? 121.392 130.868 178.296 1.00 102.85 ? 781 THR B CB  1 
ATOM   11720 O OG1 . THR B 1 761 ? 120.627 130.801 177.089 1.00 101.76 ? 781 THR B OG1 1 
ATOM   11721 C CG2 . THR B 1 761 ? 121.045 132.130 179.049 1.00 104.53 ? 781 THR B CG2 1 
ATOM   11722 N N   . CYS B 1 762 ? 123.823 133.027 177.836 1.00 93.51  ? 782 CYS B N   1 
ATOM   11723 C CA  . CYS B 1 762 ? 124.374 134.190 177.158 1.00 91.69  ? 782 CYS B CA  1 
ATOM   11724 C C   . CYS B 1 762 ? 125.599 133.774 176.340 1.00 87.42  ? 782 CYS B C   1 
ATOM   11725 O O   . CYS B 1 762 ? 125.732 134.150 175.174 1.00 85.05  ? 782 CYS B O   1 
ATOM   11726 C CB  . CYS B 1 762 ? 124.725 135.293 178.149 1.00 93.56  ? 782 CYS B CB  1 
ATOM   11727 S SG  . CYS B 1 762 ? 125.077 136.884 177.357 1.00 97.27  ? 782 CYS B SG  1 
ATOM   11728 N N   . ILE B 1 763 ? 126.473 132.970 176.959 1.00 85.74  ? 783 ILE B N   1 
ATOM   11729 C CA  . ILE B 1 763 ? 127.693 132.510 176.315 1.00 86.08  ? 783 ILE B CA  1 
ATOM   11730 C C   . ILE B 1 763 ? 127.328 131.696 175.077 1.00 84.42  ? 783 ILE B C   1 
ATOM   11731 O O   . ILE B 1 763 ? 127.923 131.878 174.013 1.00 84.89  ? 783 ILE B O   1 
ATOM   11732 C CB  . ILE B 1 763 ? 128.563 131.688 177.291 1.00 88.89  ? 783 ILE B CB  1 
ATOM   11733 C CG1 . ILE B 1 763 ? 129.153 132.548 178.414 1.00 90.48  ? 783 ILE B CG1 1 
ATOM   11734 C CG2 . ILE B 1 763 ? 129.643 130.928 176.538 1.00 89.18  ? 783 ILE B CG2 1 
ATOM   11735 C CD1 . ILE B 1 763 ? 130.188 133.556 177.960 1.00 90.67  ? 783 ILE B CD1 1 
ATOM   11736 N N   . ILE B 1 764 ? 126.354 130.791 175.221 1.00 81.64  ? 784 ILE B N   1 
ATOM   11737 C CA  . ILE B 1 764 ? 126.064 129.860 174.146 1.00 78.92  ? 784 ILE B CA  1 
ATOM   11738 C C   . ILE B 1 764 ? 125.431 130.605 172.979 1.00 75.93  ? 784 ILE B C   1 
ATOM   11739 O O   . ILE B 1 764 ? 125.730 130.292 171.833 1.00 74.16  ? 784 ILE B O   1 
ATOM   11740 C CB  . ILE B 1 764 ? 125.210 128.666 174.605 1.00 79.69  ? 784 ILE B CB  1 
ATOM   11741 C CG1 . ILE B 1 764 ? 125.029 127.670 173.463 1.00 81.57  ? 784 ILE B CG1 1 
ATOM   11742 C CG2 . ILE B 1 764 ? 123.876 129.109 175.165 1.00 79.73  ? 784 ILE B CG2 1 
ATOM   11743 C CD1 . ILE B 1 764 ? 126.297 127.314 172.735 1.00 83.08  ? 784 ILE B CD1 1 
ATOM   11744 N N   . TRP B 1 765 ? 124.582 131.594 173.259 1.00 77.46  ? 785 TRP B N   1 
ATOM   11745 C CA  . TRP B 1 765 ? 124.074 132.462 172.206 1.00 78.93  ? 785 TRP B CA  1 
ATOM   11746 C C   . TRP B 1 765 ? 125.232 133.131 171.468 1.00 81.86  ? 785 TRP B C   1 
ATOM   11747 O O   . TRP B 1 765 ? 125.212 133.225 170.246 1.00 81.22  ? 785 TRP B O   1 
ATOM   11748 C CB  . TRP B 1 765 ? 123.099 133.504 172.764 1.00 78.16  ? 785 TRP B CB  1 
ATOM   11749 C CG  . TRP B 1 765 ? 121.713 132.983 172.981 1.00 77.23  ? 785 TRP B CG  1 
ATOM   11750 C CD1 . TRP B 1 765 ? 121.344 131.898 173.724 1.00 77.56  ? 785 TRP B CD1 1 
ATOM   11751 C CD2 . TRP B 1 765 ? 120.497 133.542 172.461 1.00 76.34  ? 785 TRP B CD2 1 
ATOM   11752 N NE1 . TRP B 1 765 ? 119.986 131.739 173.697 1.00 77.86  ? 785 TRP B NE1 1 
ATOM   11753 C CE2 . TRP B 1 765 ? 119.439 132.737 172.932 1.00 76.85  ? 785 TRP B CE2 1 
ATOM   11754 C CE3 . TRP B 1 765 ? 120.205 134.640 171.647 1.00 77.30  ? 785 TRP B CE3 1 
ATOM   11755 C CZ2 . TRP B 1 765 ? 118.109 133.004 172.611 1.00 77.61  ? 785 TRP B CZ2 1 
ATOM   11756 C CZ3 . TRP B 1 765 ? 118.891 134.900 171.329 1.00 79.00  ? 785 TRP B CZ3 1 
ATOM   11757 C CH2 . TRP B 1 765 ? 117.858 134.089 171.804 1.00 79.49  ? 785 TRP B CH2 1 
ATOM   11758 N N   . LEU B 1 766 ? 126.242 133.591 172.216 1.00 85.52  ? 786 LEU B N   1 
ATOM   11759 C CA  . LEU B 1 766 ? 127.388 134.270 171.628 1.00 87.34  ? 786 LEU B CA  1 
ATOM   11760 C C   . LEU B 1 766 ? 128.238 133.316 170.785 1.00 83.95  ? 786 LEU B C   1 
ATOM   11761 O O   . LEU B 1 766 ? 128.897 133.750 169.846 1.00 84.21  ? 786 LEU B O   1 
ATOM   11762 C CB  . LEU B 1 766 ? 128.230 134.906 172.741 1.00 90.86  ? 786 LEU B CB  1 
ATOM   11763 C CG  . LEU B 1 766 ? 127.812 136.311 173.176 1.00 94.64  ? 786 LEU B CG  1 
ATOM   11764 C CD1 . LEU B 1 766 ? 128.764 136.850 174.234 1.00 95.85  ? 786 LEU B CD1 1 
ATOM   11765 C CD2 . LEU B 1 766 ? 127.755 137.260 171.986 1.00 95.30  ? 786 LEU B CD2 1 
ATOM   11766 N N   . ALA B 1 767 ? 128.216 132.021 171.114 1.00 81.69  ? 787 ALA B N   1 
ATOM   11767 C CA  . ALA B 1 767 ? 129.141 131.070 170.518 1.00 81.43  ? 787 ALA B CA  1 
ATOM   11768 C C   . ALA B 1 767 ? 128.790 130.790 169.056 1.00 79.79  ? 787 ALA B C   1 
ATOM   11769 O O   . ALA B 1 767 ? 129.688 130.612 168.241 1.00 78.96  ? 787 ALA B O   1 
ATOM   11770 C CB  . ALA B 1 767 ? 129.169 129.797 171.325 1.00 82.65  ? 787 ALA B CB  1 
ATOM   11771 N N   . PHE B 1 768 ? 127.495 130.754 168.719 1.00 79.30  ? 788 PHE B N   1 
ATOM   11772 C CA  . PHE B 1 768 ? 127.055 130.373 167.385 1.00 77.79  ? 788 PHE B CA  1 
ATOM   11773 C C   . PHE B 1 768 ? 127.001 131.556 166.420 1.00 77.39  ? 788 PHE B C   1 
ATOM   11774 O O   . PHE B 1 768 ? 126.550 131.397 165.287 1.00 77.65  ? 788 PHE B O   1 
ATOM   11775 C CB  . PHE B 1 768 ? 125.687 129.692 167.455 1.00 76.26  ? 788 PHE B CB  1 
ATOM   11776 C CG  . PHE B 1 768 ? 125.761 128.235 167.832 1.00 75.21  ? 788 PHE B CG  1 
ATOM   11777 C CD1 . PHE B 1 768 ? 125.901 127.839 169.153 1.00 74.32  ? 788 PHE B CD1 1 
ATOM   11778 C CD2 . PHE B 1 768 ? 125.729 127.256 166.849 1.00 77.50  ? 788 PHE B CD2 1 
ATOM   11779 C CE1 . PHE B 1 768 ? 125.973 126.493 169.482 1.00 75.71  ? 788 PHE B CE1 1 
ATOM   11780 C CE2 . PHE B 1 768 ? 125.809 125.913 167.181 1.00 78.67  ? 788 PHE B CE2 1 
ATOM   11781 C CZ  . PHE B 1 768 ? 125.934 125.534 168.496 1.00 77.78  ? 788 PHE B CZ  1 
ATOM   11782 N N   . VAL B 1 769 ? 127.508 132.721 166.830 1.00 76.64  ? 789 VAL B N   1 
ATOM   11783 C CA  . VAL B 1 769 ? 127.492 133.902 165.982 1.00 77.64  ? 789 VAL B CA  1 
ATOM   11784 C C   . VAL B 1 769 ? 128.332 133.665 164.726 1.00 80.93  ? 789 VAL B C   1 
ATOM   11785 O O   . VAL B 1 769 ? 127.854 133.915 163.626 1.00 81.48  ? 789 VAL B O   1 
ATOM   11786 C CB  . VAL B 1 769 ? 127.934 135.155 166.761 1.00 78.25  ? 789 VAL B CB  1 
ATOM   11787 C CG1 . VAL B 1 769 ? 128.181 136.358 165.860 1.00 79.43  ? 789 VAL B CG1 1 
ATOM   11788 C CG2 . VAL B 1 769 ? 126.916 135.504 167.836 1.00 78.45  ? 789 VAL B CG2 1 
ATOM   11789 N N   . PRO B 1 770 ? 129.602 133.203 164.814 1.00 85.67  ? 790 PRO B N   1 
ATOM   11790 C CA  . PRO B 1 770 ? 130.404 132.982 163.609 1.00 87.60  ? 790 PRO B CA  1 
ATOM   11791 C C   . PRO B 1 770 ? 129.848 131.908 162.672 1.00 89.40  ? 790 PRO B C   1 
ATOM   11792 O O   . PRO B 1 770 ? 129.919 132.067 161.456 1.00 92.30  ? 790 PRO B O   1 
ATOM   11793 C CB  . PRO B 1 770 ? 131.786 132.574 164.146 1.00 88.40  ? 790 PRO B CB  1 
ATOM   11794 C CG  . PRO B 1 770 ? 131.519 132.084 165.552 1.00 88.22  ? 790 PRO B CG  1 
ATOM   11795 C CD  . PRO B 1 770 ? 130.348 132.906 166.046 1.00 87.47  ? 790 PRO B CD  1 
ATOM   11796 N N   . ILE B 1 771 ? 129.311 130.815 163.230 1.00 86.92  ? 791 ILE B N   1 
ATOM   11797 C CA  . ILE B 1 771 ? 128.891 129.691 162.407 1.00 84.78  ? 791 ILE B CA  1 
ATOM   11798 C C   . ILE B 1 771 ? 127.572 130.025 161.717 1.00 83.14  ? 791 ILE B C   1 
ATOM   11799 O O   . ILE B 1 771 ? 127.325 129.534 160.618 1.00 82.60  ? 791 ILE B O   1 
ATOM   11800 C CB  . ILE B 1 771 ? 128.807 128.367 163.196 1.00 85.16  ? 791 ILE B CB  1 
ATOM   11801 C CG1 . ILE B 1 771 ? 128.757 127.164 162.249 1.00 85.17  ? 791 ILE B CG1 1 
ATOM   11802 C CG2 . ILE B 1 771 ? 127.634 128.362 164.164 1.00 86.16  ? 791 ILE B CG2 1 
ATOM   11803 C CD1 . ILE B 1 771 ? 128.839 125.819 162.942 1.00 84.93  ? 791 ILE B CD1 1 
ATOM   11804 N N   . TYR B 1 772 ? 126.728 130.846 162.356 1.00 83.28  ? 792 TYR B N   1 
ATOM   11805 C CA  . TYR B 1 772 ? 125.409 131.147 161.818 1.00 85.42  ? 792 TYR B CA  1 
ATOM   11806 C C   . TYR B 1 772 ? 125.537 132.249 160.768 1.00 87.54  ? 792 TYR B C   1 
ATOM   11807 O O   . TYR B 1 772 ? 125.273 132.023 159.589 1.00 88.05  ? 792 TYR B O   1 
ATOM   11808 C CB  . TYR B 1 772 ? 124.444 131.499 162.955 1.00 86.84  ? 792 TYR B CB  1 
ATOM   11809 C CG  . TYR B 1 772 ? 123.032 131.854 162.556 1.00 87.51  ? 792 TYR B CG  1 
ATOM   11810 C CD1 . TYR B 1 772 ? 122.749 133.073 161.962 1.00 88.01  ? 792 TYR B CD1 1 
ATOM   11811 C CD2 . TYR B 1 772 ? 121.975 130.986 162.779 1.00 87.16  ? 792 TYR B CD2 1 
ATOM   11812 C CE1 . TYR B 1 772 ? 121.459 133.424 161.603 1.00 88.09  ? 792 TYR B CE1 1 
ATOM   11813 C CE2 . TYR B 1 772 ? 120.679 131.319 162.421 1.00 87.82  ? 792 TYR B CE2 1 
ATOM   11814 C CZ  . TYR B 1 772 ? 120.419 132.543 161.831 1.00 88.60  ? 792 TYR B CZ  1 
ATOM   11815 O OH  . TYR B 1 772 ? 119.139 132.883 161.461 1.00 90.88  ? 792 TYR B OH  1 
ATOM   11816 N N   . PHE B 1 773 ? 125.918 133.451 161.211 1.00 90.48  ? 793 PHE B N   1 
ATOM   11817 C CA  . PHE B 1 773 ? 126.317 134.493 160.279 1.00 92.85  ? 793 PHE B CA  1 
ATOM   11818 C C   . PHE B 1 773 ? 127.715 134.122 159.796 1.00 96.58  ? 793 PHE B C   1 
ATOM   11819 O O   . PHE B 1 773 ? 128.651 134.092 160.591 1.00 95.70  ? 793 PHE B O   1 
ATOM   11820 C CB  . PHE B 1 773 ? 126.309 135.882 160.925 1.00 92.22  ? 793 PHE B CB  1 
ATOM   11821 C CG  . PHE B 1 773 ? 125.307 136.072 162.037 1.00 91.62  ? 793 PHE B CG  1 
ATOM   11822 C CD1 . PHE B 1 773 ? 123.955 136.218 161.772 1.00 92.84  ? 793 PHE B CD1 1 
ATOM   11823 C CD2 . PHE B 1 773 ? 125.723 136.077 163.359 1.00 91.59  ? 793 PHE B CD2 1 
ATOM   11824 C CE1 . PHE B 1 773 ? 123.045 136.386 162.806 1.00 93.88  ? 793 PHE B CE1 1 
ATOM   11825 C CE2 . PHE B 1 773 ? 124.814 136.240 164.393 1.00 93.00  ? 793 PHE B CE2 1 
ATOM   11826 C CZ  . PHE B 1 773 ? 123.476 136.395 164.114 1.00 93.80  ? 793 PHE B CZ  1 
ATOM   11827 N N   . GLY B 1 774 ? 127.836 133.793 158.508 1.00 101.93 ? 794 GLY B N   1 
ATOM   11828 C CA  . GLY B 1 774 ? 129.052 133.199 157.979 1.00 108.05 ? 794 GLY B CA  1 
ATOM   11829 C C   . GLY B 1 774 ? 128.732 132.046 157.035 1.00 117.36 ? 794 GLY B C   1 
ATOM   11830 O O   . GLY B 1 774 ? 128.212 132.270 155.944 1.00 120.29 ? 794 GLY B O   1 
ATOM   11831 N N   . SER B 1 775 ? 128.992 130.810 157.483 1.00 126.00 ? 795 SER B N   1 
ATOM   11832 C CA  . SER B 1 775 ? 128.948 129.644 156.611 1.00 132.43 ? 795 SER B CA  1 
ATOM   11833 C C   . SER B 1 775 ? 127.517 129.160 156.377 1.00 133.13 ? 795 SER B C   1 
ATOM   11834 O O   . SER B 1 775 ? 127.321 128.023 155.955 1.00 131.58 ? 795 SER B O   1 
ATOM   11835 C CB  . SER B 1 775 ? 129.806 128.535 157.166 1.00 135.27 ? 795 SER B CB  1 
ATOM   11836 O OG  . SER B 1 775 ? 131.160 128.948 157.266 1.00 137.89 ? 795 SER B OG  1 
ATOM   11837 N N   . ASN B 1 776 ? 126.531 130.047 156.583 1.00 134.13 ? 796 ASN B N   1 
ATOM   11838 C CA  . ASN B 1 776 ? 125.121 129.709 156.461 1.00 136.63 ? 796 ASN B CA  1 
ATOM   11839 C C   . ASN B 1 776 ? 124.823 128.523 157.378 1.00 137.15 ? 796 ASN B C   1 
ATOM   11840 O O   . ASN B 1 776 ? 125.176 128.570 158.553 1.00 139.56 ? 796 ASN B O   1 
ATOM   11841 C CB  . ASN B 1 776 ? 124.707 129.538 154.994 1.00 137.22 ? 796 ASN B CB  1 
ATOM   11842 C CG  . ASN B 1 776 ? 124.750 130.837 154.215 1.00 136.70 ? 796 ASN B CG  1 
ATOM   11843 O OD1 . ASN B 1 776 ? 125.143 131.875 154.744 1.00 134.76 ? 796 ASN B OD1 1 
ATOM   11844 N ND2 . ASN B 1 776 ? 124.345 130.790 152.957 1.00 136.70 ? 796 ASN B ND2 1 
ATOM   11845 N N   . TYR B 1 777 ? 124.184 127.471 156.849 1.00 131.60 ? 797 TYR B N   1 
ATOM   11846 C CA  . TYR B 1 777 ? 123.694 126.370 157.665 1.00 126.47 ? 797 TYR B CA  1 
ATOM   11847 C C   . TYR B 1 777 ? 122.743 126.926 158.722 1.00 116.65 ? 797 TYR B C   1 
ATOM   11848 O O   . TYR B 1 777 ? 122.968 126.779 159.922 1.00 114.88 ? 797 TYR B O   1 
ATOM   11849 C CB  . TYR B 1 777 ? 124.854 125.593 158.290 1.00 130.26 ? 797 TYR B CB  1 
ATOM   11850 C CG  . TYR B 1 777 ? 125.833 124.984 157.318 1.00 135.79 ? 797 TYR B CG  1 
ATOM   11851 C CD1 . TYR B 1 777 ? 125.612 124.971 155.947 1.00 138.66 ? 797 TYR B CD1 1 
ATOM   11852 C CD2 . TYR B 1 777 ? 127.002 124.407 157.784 1.00 140.48 ? 797 TYR B CD2 1 
ATOM   11853 C CE1 . TYR B 1 777 ? 126.521 124.399 155.072 1.00 143.49 ? 797 TYR B CE1 1 
ATOM   11854 C CE2 . TYR B 1 777 ? 127.924 123.832 156.923 1.00 143.74 ? 797 TYR B CE2 1 
ATOM   11855 C CZ  . TYR B 1 777 ? 127.684 123.828 155.560 1.00 145.50 ? 797 TYR B CZ  1 
ATOM   11856 O OH  . TYR B 1 777 ? 128.594 123.261 154.699 1.00 144.67 ? 797 TYR B OH  1 
ATOM   11857 N N   . LYS B 1 778 ? 121.668 127.562 158.243 1.00 108.99 ? 798 LYS B N   1 
ATOM   11858 C CA  . LYS B 1 778 ? 120.752 128.308 159.087 1.00 105.14 ? 798 LYS B CA  1 
ATOM   11859 C C   . LYS B 1 778 ? 119.972 127.360 159.991 1.00 99.76  ? 798 LYS B C   1 
ATOM   11860 O O   . LYS B 1 778 ? 120.064 127.459 161.209 1.00 98.54  ? 798 LYS B O   1 
ATOM   11861 C CB  . LYS B 1 778 ? 119.792 129.125 158.214 1.00 108.35 ? 798 LYS B CB  1 
ATOM   11862 C CG  . LYS B 1 778 ? 119.537 130.554 158.677 1.00 109.98 ? 798 LYS B CG  1 
ATOM   11863 C CD  . LYS B 1 778 ? 120.793 131.365 158.913 1.00 110.35 ? 798 LYS B CD  1 
ATOM   11864 C CE  . LYS B 1 778 ? 121.839 131.247 157.826 1.00 111.82 ? 798 LYS B CE  1 
ATOM   11865 N NZ  . LYS B 1 778 ? 123.095 131.923 158.230 1.00 111.94 ? 798 LYS B NZ  1 
ATOM   11866 N N   . ALA B 1 779 ? 119.212 126.446 159.378 1.00 94.17  ? 799 ALA B N   1 
ATOM   11867 C CA  . ALA B 1 779 ? 118.229 125.649 160.097 1.00 89.55  ? 799 ALA B CA  1 
ATOM   11868 C C   . ALA B 1 779 ? 118.906 124.723 161.104 1.00 85.38  ? 799 ALA B C   1 
ATOM   11869 O O   . ALA B 1 779 ? 118.445 124.604 162.236 1.00 86.29  ? 799 ALA B O   1 
ATOM   11870 C CB  . ALA B 1 779 ? 117.386 124.870 159.117 1.00 89.85  ? 799 ALA B CB  1 
ATOM   11871 N N   . ILE B 1 780 ? 119.992 124.062 160.688 1.00 80.85  ? 800 ILE B N   1 
ATOM   11872 C CA  . ILE B 1 780 ? 120.623 123.051 161.524 1.00 78.72  ? 800 ILE B CA  1 
ATOM   11873 C C   . ILE B 1 780 ? 121.185 123.703 162.785 1.00 75.58  ? 800 ILE B C   1 
ATOM   11874 O O   . ILE B 1 780 ? 120.995 123.188 163.885 1.00 75.94  ? 800 ILE B O   1 
ATOM   11875 C CB  . ILE B 1 780 ? 121.697 122.244 160.763 1.00 81.08  ? 800 ILE B CB  1 
ATOM   11876 C CG1 . ILE B 1 780 ? 122.382 121.229 161.684 1.00 83.25  ? 800 ILE B CG1 1 
ATOM   11877 C CG2 . ILE B 1 780 ? 122.718 123.142 160.081 1.00 81.98  ? 800 ILE B CG2 1 
ATOM   11878 C CD1 . ILE B 1 780 ? 123.581 120.545 161.072 1.00 85.31  ? 800 ILE B CD1 1 
ATOM   11879 N N   . THR B 1 781 ? 121.876 124.834 162.613 1.00 74.46  ? 801 THR B N   1 
ATOM   11880 C CA  . THR B 1 781 ? 122.501 125.536 163.721 1.00 73.42  ? 801 THR B CA  1 
ATOM   11881 C C   . THR B 1 781 ? 121.430 126.087 164.659 1.00 72.85  ? 801 THR B C   1 
ATOM   11882 O O   . THR B 1 781 ? 121.618 126.101 165.875 1.00 73.63  ? 801 THR B O   1 
ATOM   11883 C CB  . THR B 1 781 ? 123.409 126.664 163.216 1.00 73.27  ? 801 THR B CB  1 
ATOM   11884 O OG1 . THR B 1 781 ? 122.675 127.414 162.245 1.00 75.31  ? 801 THR B OG1 1 
ATOM   11885 C CG2 . THR B 1 781 ? 124.694 126.160 162.598 1.00 73.46  ? 801 THR B CG2 1 
ATOM   11886 N N   . MET B 1 782 ? 120.312 126.546 164.085 1.00 72.38  ? 802 MET B N   1 
ATOM   11887 C CA  . MET B 1 782 ? 119.224 127.067 164.894 1.00 71.81  ? 802 MET B CA  1 
ATOM   11888 C C   . MET B 1 782 ? 118.629 125.927 165.720 1.00 72.18  ? 802 MET B C   1 
ATOM   11889 O O   . MET B 1 782 ? 118.328 126.118 166.896 1.00 70.75  ? 802 MET B O   1 
ATOM   11890 C CB  . MET B 1 782 ? 118.139 127.705 164.023 1.00 70.86  ? 802 MET B CB  1 
ATOM   11891 C CG  . MET B 1 782 ? 117.110 128.470 164.814 1.00 70.20  ? 802 MET B CG  1 
ATOM   11892 S SD  . MET B 1 782 ? 117.830 129.923 165.609 1.00 71.14  ? 802 MET B SD  1 
ATOM   11893 C CE  . MET B 1 782 ? 117.607 131.142 164.315 1.00 71.18  ? 802 MET B CE  1 
ATOM   11894 N N   . CYS B 1 783 ? 118.480 124.745 165.104 1.00 73.61  ? 803 CYS B N   1 
ATOM   11895 C CA  . CYS B 1 783 ? 117.995 123.565 165.805 1.00 75.86  ? 803 CYS B CA  1 
ATOM   11896 C C   . CYS B 1 783 ? 118.876 123.277 167.017 1.00 75.81  ? 803 CYS B C   1 
ATOM   11897 O O   . CYS B 1 783 ? 118.370 123.123 168.125 1.00 77.61  ? 803 CYS B O   1 
ATOM   11898 C CB  . CYS B 1 783 ? 117.970 122.334 164.903 1.00 78.49  ? 803 CYS B CB  1 
ATOM   11899 S SG  . CYS B 1 783 ? 116.497 122.218 163.854 1.00 83.62  ? 803 CYS B SG  1 
ATOM   11900 N N   . PHE B 1 784 ? 120.190 123.209 166.789 1.00 73.53  ? 804 PHE B N   1 
ATOM   11901 C CA  . PHE B 1 784 ? 121.134 122.901 167.851 1.00 72.09  ? 804 PHE B CA  1 
ATOM   11902 C C   . PHE B 1 784 ? 121.059 123.964 168.941 1.00 68.36  ? 804 PHE B C   1 
ATOM   11903 O O   . PHE B 1 784 ? 121.068 123.635 170.124 1.00 68.51  ? 804 PHE B O   1 
ATOM   11904 C CB  . PHE B 1 784 ? 122.559 122.791 167.306 1.00 76.71  ? 804 PHE B CB  1 
ATOM   11905 C CG  . PHE B 1 784 ? 122.896 121.456 166.696 1.00 83.12  ? 804 PHE B CG  1 
ATOM   11906 C CD1 . PHE B 1 784 ? 122.035 120.853 165.790 1.00 86.70  ? 804 PHE B CD1 1 
ATOM   11907 C CD2 . PHE B 1 784 ? 124.084 120.813 167.008 1.00 88.28  ? 804 PHE B CD2 1 
ATOM   11908 C CE1 . PHE B 1 784 ? 122.348 119.629 165.224 1.00 90.33  ? 804 PHE B CE1 1 
ATOM   11909 C CE2 . PHE B 1 784 ? 124.398 119.589 166.437 1.00 91.88  ? 804 PHE B CE2 1 
ATOM   11910 C CZ  . PHE B 1 784 ? 123.529 118.999 165.546 1.00 92.60  ? 804 PHE B CZ  1 
ATOM   11911 N N   . SER B 1 785 ? 120.991 125.236 168.533 1.00 66.74  ? 805 SER B N   1 
ATOM   11912 C CA  . SER B 1 785 ? 121.008 126.341 169.476 1.00 66.70  ? 805 SER B CA  1 
ATOM   11913 C C   . SER B 1 785 ? 119.806 126.267 170.415 1.00 67.32  ? 805 SER B C   1 
ATOM   11914 O O   . SER B 1 785 ? 119.954 126.390 171.629 1.00 67.46  ? 805 SER B O   1 
ATOM   11915 C CB  . SER B 1 785 ? 121.056 127.657 168.753 1.00 67.17  ? 805 SER B CB  1 
ATOM   11916 O OG  . SER B 1 785 ? 121.050 128.738 169.672 1.00 67.04  ? 805 SER B OG  1 
ATOM   11917 N N   . VAL B 1 786 ? 118.616 126.068 169.843 1.00 68.20  ? 806 VAL B N   1 
ATOM   11918 C CA  . VAL B 1 786 ? 117.396 126.069 170.634 1.00 68.50  ? 806 VAL B CA  1 
ATOM   11919 C C   . VAL B 1 786 ? 117.340 124.809 171.492 1.00 66.48  ? 806 VAL B C   1 
ATOM   11920 O O   . VAL B 1 786 ? 116.887 124.862 172.629 1.00 65.54  ? 806 VAL B O   1 
ATOM   11921 C CB  . VAL B 1 786 ? 116.134 126.226 169.764 1.00 71.65  ? 806 VAL B CB  1 
ATOM   11922 C CG1 . VAL B 1 786 ? 116.177 127.517 168.959 1.00 72.46  ? 806 VAL B CG1 1 
ATOM   11923 C CG2 . VAL B 1 786 ? 115.877 125.032 168.856 1.00 73.07  ? 806 VAL B CG2 1 
ATOM   11924 N N   . SER B 1 787 ? 117.797 123.681 170.942 1.00 67.51  ? 807 SER B N   1 
ATOM   11925 C CA  . SER B 1 787 ? 117.823 122.424 171.671 1.00 69.07  ? 807 SER B CA  1 
ATOM   11926 C C   . SER B 1 787 ? 118.675 122.562 172.932 1.00 67.89  ? 807 SER B C   1 
ATOM   11927 O O   . SER B 1 787 ? 118.292 122.043 173.973 1.00 67.93  ? 807 SER B O   1 
ATOM   11928 C CB  . SER B 1 787 ? 118.301 121.298 170.775 1.00 71.58  ? 807 SER B CB  1 
ATOM   11929 O OG  . SER B 1 787 ? 118.531 120.091 171.490 1.00 73.71  ? 807 SER B OG  1 
ATOM   11930 N N   . LEU B 1 788 ? 119.816 123.265 172.846 1.00 67.71  ? 808 LEU B N   1 
ATOM   11931 C CA  . LEU B 1 788 ? 120.718 123.325 173.985 1.00 68.29  ? 808 LEU B CA  1 
ATOM   11932 C C   . LEU B 1 788 ? 120.298 124.414 174.969 1.00 67.75  ? 808 LEU B C   1 
ATOM   11933 O O   . LEU B 1 788 ? 120.302 124.165 176.173 1.00 68.89  ? 808 LEU B O   1 
ATOM   11934 C CB  . LEU B 1 788 ? 122.183 123.459 173.550 1.00 69.39  ? 808 LEU B CB  1 
ATOM   11935 C CG  . LEU B 1 788 ? 122.515 124.497 172.481 1.00 70.66  ? 808 LEU B CG  1 
ATOM   11936 C CD1 . LEU B 1 788 ? 122.540 125.890 173.064 1.00 70.82  ? 808 LEU B CD1 1 
ATOM   11937 C CD2 . LEU B 1 788 ? 123.848 124.178 171.816 1.00 70.95  ? 808 LEU B CD2 1 
ATOM   11938 N N   . SER B 1 789 ? 119.896 125.594 174.485 1.00 67.46  ? 809 SER B N   1 
ATOM   11939 C CA  . SER B 1 789 ? 119.625 126.721 175.372 1.00 67.86  ? 809 SER B CA  1 
ATOM   11940 C C   . SER B 1 789 ? 118.556 126.363 176.409 1.00 70.13  ? 809 SER B C   1 
ATOM   11941 O O   . SER B 1 789 ? 118.578 126.866 177.532 1.00 71.92  ? 809 SER B O   1 
ATOM   11942 C CB  . SER B 1 789 ? 119.238 127.954 174.598 1.00 66.60  ? 809 SER B CB  1 
ATOM   11943 O OG  . SER B 1 789 ? 120.289 128.366 173.743 1.00 66.56  ? 809 SER B OG  1 
ATOM   11944 N N   . ALA B 1 790 ? 117.628 125.480 176.026 1.00 71.35  ? 810 ALA B N   1 
ATOM   11945 C CA  . ALA B 1 790 ? 116.628 124.960 176.940 1.00 73.00  ? 810 ALA B CA  1 
ATOM   11946 C C   . ALA B 1 790 ? 117.292 124.127 178.030 1.00 76.72  ? 810 ALA B C   1 
ATOM   11947 O O   . ALA B 1 790 ? 117.122 124.430 179.204 1.00 77.17  ? 810 ALA B O   1 
ATOM   11948 C CB  . ALA B 1 790 ? 115.595 124.173 176.179 1.00 72.74  ? 810 ALA B CB  1 
ATOM   11949 N N   . THR B 1 791 ? 118.076 123.120 177.631 1.00 79.68  ? 811 THR B N   1 
ATOM   11950 C CA  . THR B 1 791 ? 118.750 122.252 178.580 1.00 81.73  ? 811 THR B CA  1 
ATOM   11951 C C   . THR B 1 791 ? 119.567 123.088 179.561 1.00 82.61  ? 811 THR B C   1 
ATOM   11952 O O   . THR B 1 791 ? 119.700 122.697 180.713 1.00 84.66  ? 811 THR B O   1 
ATOM   11953 C CB  . THR B 1 791 ? 119.611 121.206 177.857 1.00 82.35  ? 811 THR B CB  1 
ATOM   11954 O OG1 . THR B 1 791 ? 118.731 120.400 177.076 1.00 81.37  ? 811 THR B OG1 1 
ATOM   11955 C CG2 . THR B 1 791 ? 120.404 120.315 178.789 1.00 83.96  ? 811 THR B CG2 1 
ATOM   11956 N N   . VAL B 1 792 ? 120.122 124.216 179.102 1.00 80.71  ? 812 VAL B N   1 
ATOM   11957 C CA  . VAL B 1 792 ? 120.861 125.115 179.976 1.00 80.21  ? 812 VAL B CA  1 
ATOM   11958 C C   . VAL B 1 792 ? 119.950 125.562 181.120 1.00 81.16  ? 812 VAL B C   1 
ATOM   11959 O O   . VAL B 1 792 ? 120.335 125.489 182.283 1.00 81.58  ? 812 VAL B O   1 
ATOM   11960 C CB  . VAL B 1 792 ? 121.439 126.315 179.201 1.00 80.66  ? 812 VAL B CB  1 
ATOM   11961 C CG1 . VAL B 1 792 ? 121.986 127.382 180.138 1.00 81.89  ? 812 VAL B CG1 1 
ATOM   11962 C CG2 . VAL B 1 792 ? 122.514 125.886 178.213 1.00 81.25  ? 812 VAL B CG2 1 
ATOM   11963 N N   . LEU B 1 793 ? 118.755 126.061 180.785 1.00 83.95  ? 813 LEU B N   1 
ATOM   11964 C CA  . LEU B 1 793 ? 117.781 126.440 181.795 1.00 88.24  ? 813 LEU B CA  1 
ATOM   11965 C C   . LEU B 1 793 ? 117.281 125.195 182.517 1.00 93.31  ? 813 LEU B C   1 
ATOM   11966 O O   . LEU B 1 793 ? 117.470 125.056 183.723 1.00 94.85  ? 813 LEU B O   1 
ATOM   11967 C CB  . LEU B 1 793 ? 116.624 127.217 181.151 1.00 87.58  ? 813 LEU B CB  1 
ATOM   11968 C CG  . LEU B 1 793 ? 116.745 128.740 181.191 1.00 88.65  ? 813 LEU B CG  1 
ATOM   11969 C CD1 . LEU B 1 793 ? 116.905 129.236 182.625 1.00 89.49  ? 813 LEU B CD1 1 
ATOM   11970 C CD2 . LEU B 1 793 ? 117.901 129.220 180.322 1.00 89.36  ? 813 LEU B CD2 1 
ATOM   11971 N N   . LEU B 1 794 ? 116.666 124.283 181.759 1.00 98.74  ? 814 LEU B N   1 
ATOM   11972 C CA  . LEU B 1 794 ? 116.052 123.091 182.320 1.00 103.69 ? 814 LEU B CA  1 
ATOM   11973 C C   . LEU B 1 794 ? 117.072 122.301 183.137 1.00 108.18 ? 814 LEU B C   1 
ATOM   11974 O O   . LEU B 1 794 ? 116.685 121.537 184.019 1.00 109.16 ? 814 LEU B O   1 
ATOM   11975 C CB  . LEU B 1 794 ? 115.474 122.250 181.175 1.00 103.54 ? 814 LEU B CB  1 
ATOM   11976 C CG  . LEU B 1 794 ? 114.651 121.026 181.581 1.00 105.35 ? 814 LEU B CG  1 
ATOM   11977 C CD1 . LEU B 1 794 ? 113.391 121.419 182.341 1.00 106.27 ? 814 LEU B CD1 1 
ATOM   11978 C CD2 . LEU B 1 794 ? 114.290 120.201 180.357 1.00 105.85 ? 814 LEU B CD2 1 
ATOM   11979 N N   . GLY B 1 795 ? 118.366 122.504 182.857 1.00 112.49 ? 815 GLY B N   1 
ATOM   11980 C CA  . GLY B 1 795 ? 119.426 121.760 183.518 1.00 116.87 ? 815 GLY B CA  1 
ATOM   11981 C C   . GLY B 1 795 ? 119.881 122.419 184.817 1.00 120.52 ? 815 GLY B C   1 
ATOM   11982 O O   . GLY B 1 795 ? 120.199 121.724 185.775 1.00 121.83 ? 815 GLY B O   1 
ATOM   11983 N N   . CYS B 1 796 ? 119.890 123.757 184.840 1.00 122.19 ? 816 CYS B N   1 
ATOM   11984 C CA  . CYS B 1 796 ? 120.405 124.500 185.977 1.00 124.02 ? 816 CYS B CA  1 
ATOM   11985 C C   . CYS B 1 796 ? 119.256 125.043 186.820 1.00 124.63 ? 816 CYS B C   1 
ATOM   11986 O O   . CYS B 1 796 ? 119.383 125.158 188.036 1.00 126.76 ? 816 CYS B O   1 
ATOM   11987 C CB  . CYS B 1 796 ? 121.294 125.649 185.521 1.00 124.75 ? 816 CYS B CB  1 
ATOM   11988 S SG  . CYS B 1 796 ? 122.794 125.112 184.657 1.00 127.23 ? 816 CYS B SG  1 
ATOM   11989 N N   . MET B 1 797 ? 118.130 125.366 186.178 1.00 124.35 ? 817 MET B N   1 
ATOM   11990 C CA  . MET B 1 797 ? 117.061 126.055 186.881 1.00 125.80 ? 817 MET B CA  1 
ATOM   11991 C C   . MET B 1 797 ? 116.251 125.074 187.727 1.00 129.34 ? 817 MET B C   1 
ATOM   11992 O O   . MET B 1 797 ? 116.236 125.197 188.946 1.00 131.72 ? 817 MET B O   1 
ATOM   11993 C CB  . MET B 1 797 ? 116.114 126.805 185.936 1.00 124.13 ? 817 MET B CB  1 
ATOM   11994 C CG  . MET B 1 797 ? 115.988 128.289 186.250 1.00 122.45 ? 817 MET B CG  1 
ATOM   11995 S SD  . MET B 1 797 ? 114.306 128.908 185.982 1.00 121.64 ? 817 MET B SD  1 
ATOM   11996 C CE  . MET B 1 797 ? 113.564 128.457 187.549 1.00 121.36 ? 817 MET B CE  1 
ATOM   11997 N N   . PHE B 1 798 ? 115.546 124.142 187.075 1.00 132.72 ? 818 PHE B N   1 
ATOM   11998 C CA  . PHE B 1 798 ? 114.444 123.436 187.714 1.00 137.34 ? 818 PHE B CA  1 
ATOM   11999 C C   . PHE B 1 798 ? 114.940 122.301 188.605 1.00 139.96 ? 818 PHE B C   1 
ATOM   12000 O O   . PHE B 1 798 ? 114.529 122.206 189.760 1.00 139.97 ? 818 PHE B O   1 
ATOM   12001 C CB  . PHE B 1 798 ? 113.462 122.933 186.655 1.00 138.82 ? 818 PHE B CB  1 
ATOM   12002 C CG  . PHE B 1 798 ? 112.609 124.025 186.064 1.00 141.86 ? 818 PHE B CG  1 
ATOM   12003 C CD1 . PHE B 1 798 ? 111.739 124.742 186.871 1.00 144.44 ? 818 PHE B CD1 1 
ATOM   12004 C CD2 . PHE B 1 798 ? 112.680 124.348 184.716 1.00 144.08 ? 818 PHE B CD2 1 
ATOM   12005 C CE1 . PHE B 1 798 ? 110.950 125.753 186.345 1.00 146.12 ? 818 PHE B CE1 1 
ATOM   12006 C CE2 . PHE B 1 798 ? 111.894 125.363 184.192 1.00 146.39 ? 818 PHE B CE2 1 
ATOM   12007 C CZ  . PHE B 1 798 ? 111.032 126.063 185.009 1.00 146.95 ? 818 PHE B CZ  1 
ATOM   12008 N N   . VAL B 1 799 ? 115.811 121.447 188.053 1.00 142.41 ? 819 VAL B N   1 
ATOM   12009 C CA  . VAL B 1 799 ? 116.084 120.127 188.605 1.00 145.51 ? 819 VAL B CA  1 
ATOM   12010 C C   . VAL B 1 799 ? 116.788 120.202 189.959 1.00 148.37 ? 819 VAL B C   1 
ATOM   12011 O O   . VAL B 1 799 ? 116.778 119.209 190.687 1.00 148.92 ? 819 VAL B O   1 
ATOM   12012 C CB  . VAL B 1 799 ? 116.860 119.228 187.617 1.00 145.76 ? 819 VAL B CB  1 
ATOM   12013 C CG1 . VAL B 1 799 ? 116.079 119.013 186.329 1.00 146.43 ? 819 VAL B CG1 1 
ATOM   12014 C CG2 . VAL B 1 799 ? 118.264 119.733 187.314 1.00 144.68 ? 819 VAL B CG2 1 
ATOM   12015 N N   . PRO B 1 800 ? 117.456 121.315 190.353 1.00 151.70 ? 820 PRO B N   1 
ATOM   12016 C CA  . PRO B 1 800 ? 117.633 121.633 191.768 1.00 154.11 ? 820 PRO B CA  1 
ATOM   12017 C C   . PRO B 1 800 ? 116.405 121.287 192.603 1.00 156.65 ? 820 PRO B C   1 
ATOM   12018 O O   . PRO B 1 800 ? 116.496 120.438 193.483 1.00 157.61 ? 820 PRO B O   1 
ATOM   12019 C CB  . PRO B 1 800 ? 117.888 123.144 191.732 1.00 154.18 ? 820 PRO B CB  1 
ATOM   12020 C CG  . PRO B 1 800 ? 118.667 123.336 190.452 1.00 154.09 ? 820 PRO B CG  1 
ATOM   12021 C CD  . PRO B 1 800 ? 118.185 122.262 189.496 1.00 152.83 ? 820 PRO B CD  1 
ATOM   12022 N N   . LYS B 1 801 ? 115.253 121.891 192.289 1.00 158.58 ? 821 LYS B N   1 
ATOM   12023 C CA  . LYS B 1 801 ? 114.029 121.608 193.020 1.00 161.18 ? 821 LYS B CA  1 
ATOM   12024 C C   . LYS B 1 801 ? 113.709 120.113 192.942 1.00 165.38 ? 821 LYS B C   1 
ATOM   12025 O O   . LYS B 1 801 ? 113.275 119.520 193.929 1.00 165.65 ? 821 LYS B O   1 
ATOM   12026 C CB  . LYS B 1 801 ? 112.883 122.476 192.493 1.00 158.55 ? 821 LYS B CB  1 
ATOM   12027 C CG  . LYS B 1 801 ? 113.056 123.969 192.744 1.00 154.78 ? 821 LYS B CG  1 
ATOM   12028 C CD  . LYS B 1 801 ? 111.958 124.823 192.144 1.00 152.41 ? 821 LYS B CD  1 
ATOM   12029 C CE  . LYS B 1 801 ? 111.987 124.857 190.630 1.00 152.50 ? 821 LYS B CE  1 
ATOM   12030 N NZ  . LYS B 1 801 ? 113.210 125.521 190.122 1.00 152.33 ? 821 LYS B NZ  1 
ATOM   12031 N N   . VAL B 1 802 ? 113.874 119.529 191.749 1.00 169.19 ? 822 VAL B N   1 
ATOM   12032 C CA  . VAL B 1 802 ? 113.598 118.115 191.541 1.00 173.85 ? 822 VAL B CA  1 
ATOM   12033 C C   . VAL B 1 802 ? 114.599 117.289 192.346 1.00 179.75 ? 822 VAL B C   1 
ATOM   12034 O O   . VAL B 1 802 ? 114.246 116.236 192.871 1.00 181.89 ? 822 VAL B O   1 
ATOM   12035 C CB  . VAL B 1 802 ? 113.612 117.728 190.047 1.00 173.58 ? 822 VAL B CB  1 
ATOM   12036 C CG1 . VAL B 1 802 ? 113.364 116.240 189.846 1.00 172.54 ? 822 VAL B CG1 1 
ATOM   12037 C CG2 . VAL B 1 802 ? 112.609 118.542 189.244 1.00 173.66 ? 822 VAL B CG2 1 
ATOM   12038 N N   . TYR B 1 803 ? 115.847 117.768 192.442 1.00 186.26 ? 823 TYR B N   1 
ATOM   12039 C CA  . TYR B 1 803 ? 116.863 117.141 193.275 1.00 193.67 ? 823 TYR B CA  1 
ATOM   12040 C C   . TYR B 1 803 ? 116.349 117.005 194.709 1.00 193.05 ? 823 TYR B C   1 
ATOM   12041 O O   . TYR B 1 803 ? 116.512 115.953 195.321 1.00 190.65 ? 823 TYR B O   1 
ATOM   12042 C CB  . TYR B 1 803 ? 118.171 117.939 193.225 1.00 199.65 ? 823 TYR B CB  1 
ATOM   12043 C CG  . TYR B 1 803 ? 119.411 117.265 193.766 1.00 205.24 ? 823 TYR B CG  1 
ATOM   12044 C CD1 . TYR B 1 803 ? 119.446 115.919 194.109 1.00 207.43 ? 823 TYR B CD1 1 
ATOM   12045 C CD2 . TYR B 1 803 ? 120.578 117.996 193.924 1.00 206.30 ? 823 TYR B CD2 1 
ATOM   12046 C CE1 . TYR B 1 803 ? 120.599 115.326 194.597 1.00 209.78 ? 823 TYR B CE1 1 
ATOM   12047 C CE2 . TYR B 1 803 ? 121.740 117.418 194.410 1.00 208.35 ? 823 TYR B CE2 1 
ATOM   12048 C CZ  . TYR B 1 803 ? 121.751 116.077 194.749 1.00 210.66 ? 823 TYR B CZ  1 
ATOM   12049 O OH  . TYR B 1 803 ? 122.899 115.495 195.233 1.00 209.58 ? 823 TYR B OH  1 
ATOM   12050 N N   . ILE B 1 804 ? 115.693 118.060 195.213 1.00 195.36 ? 824 ILE B N   1 
ATOM   12051 C CA  . ILE B 1 804 ? 115.157 118.078 196.568 1.00 198.39 ? 824 ILE B CA  1 
ATOM   12052 C C   . ILE B 1 804 ? 114.087 116.998 196.709 1.00 198.77 ? 824 ILE B C   1 
ATOM   12053 O O   . ILE B 1 804 ? 114.125 116.193 197.638 1.00 199.48 ? 824 ILE B O   1 
ATOM   12054 C CB  . ILE B 1 804 ? 114.584 119.465 196.936 1.00 199.85 ? 824 ILE B CB  1 
ATOM   12055 C CG1 . ILE B 1 804 ? 115.545 120.616 196.622 1.00 199.57 ? 824 ILE B CG1 1 
ATOM   12056 C CG2 . ILE B 1 804 ? 114.153 119.479 198.393 1.00 201.11 ? 824 ILE B CG2 1 
ATOM   12057 C CD1 . ILE B 1 804 ? 116.942 120.407 197.152 1.00 200.81 ? 824 ILE B CD1 1 
ATOM   12058 N N   . ILE B 1 805 ? 113.137 116.991 195.766 1.00 199.35 ? 825 ILE B N   1 
ATOM   12059 C CA  . ILE B 1 805 ? 112.061 116.012 195.747 1.00 201.62 ? 825 ILE B CA  1 
ATOM   12060 C C   . ILE B 1 805 ? 112.642 114.598 195.803 1.00 206.45 ? 825 ILE B C   1 
ATOM   12061 O O   . ILE B 1 805 ? 112.070 113.735 196.464 1.00 204.37 ? 825 ILE B O   1 
ATOM   12062 C CB  . ILE B 1 805 ? 111.143 116.245 194.525 1.00 198.28 ? 825 ILE B CB  1 
ATOM   12063 C CG1 . ILE B 1 805 ? 110.311 117.520 194.720 1.00 195.38 ? 825 ILE B CG1 1 
ATOM   12064 C CG2 . ILE B 1 805 ? 110.275 115.021 194.239 1.00 196.84 ? 825 ILE B CG2 1 
ATOM   12065 C CD1 . ILE B 1 805 ? 109.318 117.832 193.612 1.00 195.27 ? 825 ILE B CD1 1 
ATOM   12066 N N   . LEU B 1 806 ? 113.783 114.386 195.130 1.00 213.04 ? 826 LEU B N   1 
ATOM   12067 C CA  . LEU B 1 806 ? 114.422 113.080 195.037 1.00 219.37 ? 826 LEU B CA  1 
ATOM   12068 C C   . LEU B 1 806 ? 115.250 112.734 196.278 1.00 221.28 ? 826 LEU B C   1 
ATOM   12069 O O   . LEU B 1 806 ? 115.559 111.560 196.475 1.00 219.27 ? 826 LEU B O   1 
ATOM   12070 C CB  . LEU B 1 806 ? 115.306 113.039 193.783 1.00 223.04 ? 826 LEU B CB  1 
ATOM   12071 C CG  . LEU B 1 806 ? 114.682 112.360 192.565 1.00 225.71 ? 826 LEU B CG  1 
ATOM   12072 C CD1 . LEU B 1 806 ? 114.249 110.940 192.906 1.00 224.97 ? 826 LEU B CD1 1 
ATOM   12073 C CD2 . LEU B 1 806 ? 113.508 113.166 192.029 1.00 226.64 ? 826 LEU B CD2 1 
ATOM   12074 N N   . ALA B 1 807 ? 115.677 113.742 197.049 1.00 223.93 ? 827 ALA B N   1 
ATOM   12075 C CA  . ALA B 1 807 ? 116.333 113.527 198.326 1.00 224.63 ? 827 ALA B CA  1 
ATOM   12076 C C   . ALA B 1 807 ? 115.295 113.026 199.336 1.00 224.16 ? 827 ALA B C   1 
ATOM   12077 O O   . ALA B 1 807 ? 115.703 112.738 200.475 1.00 222.48 ? 827 ALA B O   1 
ATOM   12078 C CB  . ALA B 1 807 ? 116.984 114.811 198.788 1.00 223.13 ? 827 ALA B CB  1 
HETATM 12079 C C1  . NAG C 2 .   ? 131.326 154.714 103.828 1.00 101.24 ? 901 NAG A C1  1 
HETATM 12080 C C2  . NAG C 2 .   ? 130.494 155.900 104.304 1.00 106.26 ? 901 NAG A C2  1 
HETATM 12081 C C3  . NAG C 2 .   ? 131.327 156.784 105.225 1.00 109.70 ? 901 NAG A C3  1 
HETATM 12082 C C4  . NAG C 2 .   ? 131.824 155.965 106.407 1.00 111.32 ? 901 NAG A C4  1 
HETATM 12083 C C5  . NAG C 2 .   ? 132.642 154.773 105.912 1.00 109.69 ? 901 NAG A C5  1 
HETATM 12084 C C6  . NAG C 2 .   ? 132.162 153.457 106.484 1.00 109.83 ? 901 NAG A C6  1 
HETATM 12085 C C7  . NAG C 2 .   ? 130.599 157.311 102.281 1.00 109.38 ? 901 NAG A C7  1 
HETATM 12086 C C8  . NAG C 2 .   ? 129.795 158.065 101.265 1.00 110.53 ? 901 NAG A C8  1 
HETATM 12087 N N2  . NAG C 2 .   ? 129.902 156.658 103.218 1.00 107.46 ? 901 NAG A N2  1 
HETATM 12088 O O3  . NAG C 2 .   ? 130.549 157.889 105.660 1.00 110.84 ? 901 NAG A O3  1 
HETATM 12089 O O4  . NAG C 2 .   ? 132.638 156.786 107.242 1.00 111.99 ? 901 NAG A O4  1 
HETATM 12090 O O5  . NAG C 2 .   ? 132.606 154.658 104.470 1.00 105.42 ? 901 NAG A O5  1 
HETATM 12091 O O6  . NAG C 2 .   ? 132.476 153.356 107.872 1.00 110.43 ? 901 NAG A O6  1 
HETATM 12092 O O7  . NAG C 2 .   ? 131.826 157.297 102.249 1.00 109.36 ? 901 NAG A O7  1 
HETATM 12093 C C01 . QUS D 3 .   ? 128.185 144.312 74.538  1.00 33.52  ? 902 QUS A C01 1 
HETATM 12094 C C02 . QUS D 3 .   ? 128.343 145.739 75.070  1.00 34.63  ? 902 QUS A C02 1 
HETATM 12095 C C03 . QUS D 3 .   ? 127.845 146.759 74.040  1.00 35.46  ? 902 QUS A C03 1 
HETATM 12096 C C04 . QUS D 3 .   ? 125.821 148.268 74.148  1.00 37.92  ? 902 QUS A C04 1 
HETATM 12097 C C05 . QUS D 3 .   ? 124.267 146.796 74.681  1.00 37.10  ? 902 QUS A C05 1 
HETATM 12098 N NP3 . QUS D 3 .   ? 129.768 145.997 75.406  1.00 35.14  ? 902 QUS A NP3 1 
HETATM 12099 N N14 . QUS D 3 .   ? 126.439 147.082 74.233  1.00 36.56  ? 902 QUS A N14 1 
HETATM 12100 N N15 . QUS D 3 .   ? 124.489 148.091 74.416  1.00 37.54  ? 902 QUS A N15 1 
HETATM 12101 O O16 . QUS D 3 .   ? 127.025 143.927 74.289  1.00 34.08  ? 902 QUS A O16 1 
HETATM 12102 O O17 . QUS D 3 .   ? 129.223 143.646 74.385  1.00 32.33  ? 902 QUS A O17 1 
HETATM 12103 O O18 . QUS D 3 .   ? 126.362 149.325 73.876  1.00 39.11  ? 902 QUS A O18 1 
HETATM 12104 O O19 . QUS D 3 .   ? 123.239 146.235 74.959  1.00 37.43  ? 902 QUS A O19 1 
HETATM 12105 O O20 . QUS D 3 .   ? 125.451 146.123 74.581  1.00 36.63  ? 902 QUS A O20 1 
HETATM 12106 O O1  . XQT E 4 .   ? 139.463 129.497 166.743 1.00 70.85  ? 903 XQT A O1  1 
HETATM 12107 C C1  . XQT E 4 .   ? 140.496 131.615 165.059 1.00 70.24  ? 903 XQT A C1  1 
HETATM 12108 C C2  . XQT E 4 .   ? 141.287 130.400 165.492 1.00 70.09  ? 903 XQT A C2  1 
HETATM 12109 C C3  . XQT E 4 .   ? 140.402 129.143 165.714 1.00 71.40  ? 903 XQT A C3  1 
HETATM 12110 C C4  . XQT E 4 .   ? 139.616 128.765 164.468 1.00 71.89  ? 903 XQT A C4  1 
HETATM 12111 C C5  . XQT E 4 .   ? 141.199 127.956 166.231 1.00 71.87  ? 903 XQT A C5  1 
HETATM 12112 N N1  . XQT E 4 .   ? 142.058 130.733 166.691 1.00 70.13  ? 903 XQT A N1  1 
HETATM 12113 C C6  . XQT E 4 .   ? 143.379 130.585 166.774 1.00 70.22  ? 903 XQT A C6  1 
HETATM 12114 C C7  . XQT E 4 .   ? 144.021 131.136 168.022 1.00 69.38  ? 903 XQT A C7  1 
HETATM 12115 C C8  . XQT E 4 .   ? 145.392 131.037 168.184 1.00 68.81  ? 903 XQT A C8  1 
HETATM 12116 C C9  . XQT E 4 .   ? 145.962 131.552 169.332 1.00 69.44  ? 903 XQT A C9  1 
HETATM 12117 C C10 . XQT E 4 .   ? 145.161 132.142 170.300 1.00 68.41  ? 903 XQT A C10 1 
HETATM 12118 C C11 . XQT E 4 .   ? 145.701 132.692 171.510 1.00 69.16  ? 903 XQT A C11 1 
HETATM 12119 C C12 . XQT E 4 .   ? 146.197 133.117 172.510 1.00 71.81  ? 903 XQT A C12 1 
HETATM 12120 C C13 . XQT E 4 .   ? 146.731 133.615 173.747 1.00 74.63  ? 903 XQT A C13 1 
HETATM 12121 C C14 . XQT E 4 .   ? 148.106 133.690 173.945 1.00 76.54  ? 903 XQT A C14 1 
HETATM 12122 C C15 . XQT E 4 .   ? 148.586 134.170 175.137 1.00 78.08  ? 903 XQT A C15 1 
HETATM 12123 F F1  . XQT E 4 .   ? 149.932 134.233 175.318 1.00 80.74  ? 903 XQT A F1  1 
HETATM 12124 C C16 . XQT E 4 .   ? 147.771 134.588 176.152 1.00 76.70  ? 903 XQT A C16 1 
HETATM 12125 C C17 . XQT E 4 .   ? 146.408 134.519 175.957 1.00 75.62  ? 903 XQT A C17 1 
HETATM 12126 C C18 . XQT E 4 .   ? 145.883 134.042 174.769 1.00 75.31  ? 903 XQT A C18 1 
HETATM 12127 C C19 . XQT E 4 .   ? 143.782 132.193 170.044 1.00 67.73  ? 903 XQT A C19 1 
HETATM 12128 N N2  . XQT E 4 .   ? 143.218 131.703 168.932 1.00 68.61  ? 903 XQT A N2  1 
HETATM 12129 O O2  . XQT E 4 .   ? 144.061 130.052 165.901 1.00 70.83  ? 903 XQT A O2  1 
HETATM 12130 C C1  . NAG F 2 .   ? 131.595 107.474 105.467 1.00 109.12 ? 901 NAG B C1  1 
HETATM 12131 C C2  . NAG F 2 .   ? 130.131 107.392 105.853 1.00 114.60 ? 901 NAG B C2  1 
HETATM 12132 C C3  . NAG F 2 .   ? 129.565 106.007 105.565 1.00 117.75 ? 901 NAG B C3  1 
HETATM 12133 C C4  . NAG F 2 .   ? 130.541 104.890 105.934 1.00 118.50 ? 901 NAG B C4  1 
HETATM 12134 C C5  . NAG F 2 .   ? 131.884 105.063 105.225 1.00 116.71 ? 901 NAG B C5  1 
HETATM 12135 C C6  . NAG F 2 .   ? 132.090 104.073 104.093 1.00 117.48 ? 901 NAG B C6  1 
HETATM 12136 C C7  . NAG F 2 .   ? 129.577 109.044 107.544 1.00 119.05 ? 901 NAG B C7  1 
HETATM 12137 C C8  . NAG F 2 .   ? 129.818 109.492 108.954 1.00 122.63 ? 901 NAG B C8  1 
HETATM 12138 N N2  . NAG F 2 .   ? 129.994 107.819 107.229 1.00 116.51 ? 901 NAG B N2  1 
HETATM 12139 O O3  . NAG F 2 .   ? 129.215 105.950 104.187 1.00 118.06 ? 901 NAG B O3  1 
HETATM 12140 O O4  . NAG F 2 .   ? 130.765 104.900 107.342 1.00 118.25 ? 901 NAG B O4  1 
HETATM 12141 O O5  . NAG F 2 .   ? 131.990 106.376 104.640 1.00 112.00 ? 901 NAG B O5  1 
HETATM 12142 O O6  . NAG F 2 .   ? 133.059 104.526 103.135 1.00 116.38 ? 901 NAG B O6  1 
HETATM 12143 O O7  . NAG F 2 .   ? 129.027 109.762 106.717 1.00 118.31 ? 901 NAG B O7  1 
HETATM 12144 C C01 . QUS G 3 .   ? 132.545 116.214 75.289  1.00 33.82  ? 902 QUS B C01 1 
HETATM 12145 C C02 . QUS G 3 .   ? 133.476 115.059 75.675  1.00 34.35  ? 902 QUS B C02 1 
HETATM 12146 C C03 . QUS G 3 .   ? 134.045 114.383 74.424  1.00 34.32  ? 902 QUS B C03 1 
HETATM 12147 C C04 . QUS G 3 .   ? 135.860 112.620 74.374  1.00 34.52  ? 902 QUS B C04 1 
HETATM 12148 C C05 . QUS G 3 .   ? 137.474 113.728 75.396  1.00 33.72  ? 902 QUS B C05 1 
HETATM 12149 N NP3 . QUS G 3 .   ? 132.755 114.060 76.512  1.00 34.33  ? 902 QUS B NP3 1 
HETATM 12150 N N14 . QUS G 3 .   ? 135.364 113.826 74.679  1.00 34.32  ? 902 QUS B N14 1 
HETATM 12151 N N15 . QUS G 3 .   ? 137.157 112.562 74.815  1.00 34.29  ? 902 QUS B N15 1 
HETATM 12152 O O16 . QUS G 3 .   ? 133.045 117.155 74.630  1.00 33.05  ? 902 QUS B O16 1 
HETATM 12153 O O17 . QUS G 3 .   ? 131.358 116.129 75.654  1.00 34.18  ? 902 QUS B O17 1 
HETATM 12154 O O18 . QUS G 3 .   ? 135.265 111.732 73.793  1.00 34.81  ? 902 QUS B O18 1 
HETATM 12155 O O19 . QUS G 3 .   ? 138.505 114.074 75.909  1.00 33.83  ? 902 QUS B O19 1 
HETATM 12156 O O20 . QUS G 3 .   ? 136.389 114.552 75.342  1.00 33.83  ? 902 QUS B O20 1 
HETATM 12157 O O1  . XQT H 4 .   ? 123.424 132.218 168.353 1.00 90.08  ? 903 XQT B O1  1 
HETATM 12158 C C1  . XQT H 4 .   ? 122.215 130.842 166.165 1.00 87.27  ? 903 XQT B C1  1 
HETATM 12159 C C2  . XQT H 4 .   ? 121.630 132.089 166.800 1.00 87.50  ? 903 XQT B C2  1 
HETATM 12160 C C3  . XQT H 4 .   ? 122.719 133.020 167.394 1.00 89.70  ? 903 XQT B C3  1 
HETATM 12161 C C4  . XQT H 4 .   ? 123.719 133.481 166.345 1.00 90.95  ? 903 XQT B C4  1 
HETATM 12162 C C5  . XQT H 4 .   ? 122.142 134.200 168.161 1.00 90.49  ? 903 XQT B C5  1 
HETATM 12163 N N1  . XQT H 4 .   ? 120.656 131.712 167.826 1.00 85.92  ? 903 XQT B N1  1 
HETATM 12164 C C6  . XQT H 4 .   ? 119.363 132.037 167.786 1.00 83.88  ? 903 XQT B C6  1 
HETATM 12165 C C7  . XQT H 4 .   ? 118.537 131.444 168.897 1.00 83.44  ? 903 XQT B C7  1 
HETATM 12166 C C8  . XQT H 4 .   ? 117.162 131.593 168.899 1.00 82.99  ? 903 XQT B C8  1 
HETATM 12167 C C9  . XQT H 4 .   ? 116.439 131.030 169.934 1.00 83.66  ? 903 XQT B C9  1 
HETATM 12168 C C10 . XQT H 4 .   ? 117.094 130.331 170.939 1.00 84.19  ? 903 XQT B C10 1 
HETATM 12169 C C11 . XQT H 4 .   ? 116.390 129.734 172.037 1.00 86.40  ? 903 XQT B C11 1 
HETATM 12170 C C12 . XQT H 4 .   ? 115.849 129.218 172.969 1.00 89.37  ? 903 XQT B C12 1 
HETATM 12171 C C13 . XQT H 4 .   ? 115.154 128.653 174.092 1.00 89.21  ? 903 XQT B C13 1 
HETATM 12172 C C14 . XQT H 4 .   ? 113.769 128.511 174.075 1.00 89.19  ? 903 XQT B C14 1 
HETATM 12173 C C15 . XQT H 4 .   ? 113.138 127.961 175.165 1.00 89.76  ? 903 XQT B C15 1 
HETATM 12174 F F1  . XQT H 4 .   ? 111.785 127.828 175.139 1.00 91.96  ? 903 XQT B F1  1 
HETATM 12175 C C16 . XQT H 4 .   ? 113.810 127.549 176.282 1.00 90.21  ? 903 XQT B C16 1 
HETATM 12176 C C17 . XQT H 4 .   ? 115.180 127.695 176.301 1.00 88.80  ? 903 XQT B C17 1 
HETATM 12177 C C18 . XQT H 4 .   ? 115.855 128.230 175.219 1.00 88.63  ? 903 XQT B C18 1 
HETATM 12178 C C19 . XQT H 4 .   ? 118.489 130.232 170.846 1.00 83.74  ? 903 XQT B C19 1 
HETATM 12179 N N2  . XQT H 4 .   ? 119.200 130.778 169.851 1.00 83.73  ? 903 XQT B N2  1 
HETATM 12180 O O2  . XQT H 4 .   ? 118.848 132.744 166.920 1.00 82.55  ? 903 XQT B O2  1 
# 
