data_8WZ8
# 
_entry.id   8WZ8 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8WZ8         pdb_00008wz8 10.2210/pdb8wz8/pdb 
WWPDB D_1300042191 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-06 
2 'Structure model' 1 1 2024-11-20 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_ASTM'         
4  2 'Structure model' '_citation.journal_id_CSD'          
5  2 'Structure model' '_citation.journal_id_ISSN'         
6  2 'Structure model' '_citation.journal_volume'          
7  2 'Structure model' '_citation.page_first'              
8  2 'Structure model' '_citation.page_last'               
9  2 'Structure model' '_citation.pdbx_database_id_DOI'    
10 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
11 2 'Structure model' '_citation.title'                   
12 2 'Structure model' '_citation.year'                    
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8WZ8 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-01 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 hhge@ahu.edu.cn Honghua Ge ? 'principal investigator/group leader' 0000-0001-7176-6853 
4 jmma@ahu.edu.cn Jinming Ma ? 'principal investigator/group leader' 0000-0002-3199-9860 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Gao, Y.S.'  1 0009-0005-6639-4713 
'Xie, R.'    2 ?                   
'Chen, Y.N.' 3 ?                   
'Ma, J.M.'   4 0000-0002-3199-9860 
'Ge, H.H.'   5 0000-0001-7176-6853 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Int.J.Biol.Macromol. 
_citation.journal_id_ASTM           IJBMDR 
_citation.journal_id_CSD            0708 
_citation.journal_id_ISSN           0141-8130 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            270 
_citation.language                  ? 
_citation.page_first                132289 
_citation.page_last                 132289 
_citation.title                     
'Structural basis for substrate recognition by a S-adenosylhomocysteine hydrolase Lpg2021 from Legionella pneumophila.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.ijbiomac.2024.132289 
_citation.pdbx_database_id_PubMed   38735607 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Gao, Y.'  1  ? 
primary 'Xie, R.'  2  ? 
primary 'Chen, Y.' 3  ? 
primary 'Yang, B.' 4  ? 
primary 'Wang, M.' 5  ? 
primary 'Hua, L.'  6  ? 
primary 'Wang, X.' 7  ? 
primary 'Wang, W.' 8  ? 
primary 'Wang, N.' 9  ? 
primary 'Ge, H.'   10 ? 
primary 'Ma, J.'   11 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Adenosylhomocysteinase            48285.000 1   ? T67A,Q69A ? ? 
2 non-polymer syn NICOTINAMIDE-ADENINE-DINUCLEOTIDE 663.425   1   ? ?         ? ? 
3 non-polymer syn 'SULFATE ION'                     96.063    1   ? ?         ? ? 
4 water       nat water                             18.015    122 ? ?         ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGHHHHHHHHQDYKVAEISLADWGRKEIAIAETEMPGLMALREEFSAKKPLQGARIAGCLHMAIATAVLIETLVALGAEV
RWSSCNIFSTQDHAASAIAAKGIPVFAWKGETEEEYWWCVEQTLSGPNGWTPNLLLDDGGDLTQVVHQKHPKLLTAIKGV
SEETTTGVARLYEMAKHGQLKIPAINVNNAVTKSKFDNLYGCRESLLDGLKRATDVMIAGKVALILGYGDVGKGCAQALR
GQGATVLVAEIDPICALQAAMEGYRVVTLDDVAEQVDIVVTATGNYHVVTHDHMKRMRNQAILCNIGHFDSEIDIQSLKQ
YQWENIKPQVDHVIFPDGKRIIILAEGRLVNLGCATGHPSFVMSASFTNQVLAQIELFQNSSQYQNQVYVLPKVLDEKVA
RLHLGRIGAKLTQLSNEQADYIGVDKNGPYKPDHYRY
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGHHHHHHHHQDYKVAEISLADWGRKEIAIAETEMPGLMALREEFSAKKPLQGARIAGCLHMAIATAVLIETLVALGAEV
RWSSCNIFSTQDHAASAIAAKGIPVFAWKGETEEEYWWCVEQTLSGPNGWTPNLLLDDGGDLTQVVHQKHPKLLTAIKGV
SEETTTGVARLYEMAKHGQLKIPAINVNNAVTKSKFDNLYGCRESLLDGLKRATDVMIAGKVALILGYGDVGKGCAQALR
GQGATVLVAEIDPICALQAAMEGYRVVTLDDVAEQVDIVVTATGNYHVVTHDHMKRMRNQAILCNIGHFDSEIDIQSLKQ
YQWENIKPQVDHVIFPDGKRIIILAEGRLVNLGCATGHPSFVMSASFTNQVLAQIELFQNSSQYQNQVYVLPKVLDEKVA
RLHLGRIGAKLTQLSNEQADYIGVDKNGPYKPDHYRY
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 NICOTINAMIDE-ADENINE-DINUCLEOTIDE NAD 
3 'SULFATE ION'                     SO4 
4 water                             HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   HIS n 
1 4   HIS n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  GLN n 
1 12  ASP n 
1 13  TYR n 
1 14  LYS n 
1 15  VAL n 
1 16  ALA n 
1 17  GLU n 
1 18  ILE n 
1 19  SER n 
1 20  LEU n 
1 21  ALA n 
1 22  ASP n 
1 23  TRP n 
1 24  GLY n 
1 25  ARG n 
1 26  LYS n 
1 27  GLU n 
1 28  ILE n 
1 29  ALA n 
1 30  ILE n 
1 31  ALA n 
1 32  GLU n 
1 33  THR n 
1 34  GLU n 
1 35  MET n 
1 36  PRO n 
1 37  GLY n 
1 38  LEU n 
1 39  MET n 
1 40  ALA n 
1 41  LEU n 
1 42  ARG n 
1 43  GLU n 
1 44  GLU n 
1 45  PHE n 
1 46  SER n 
1 47  ALA n 
1 48  LYS n 
1 49  LYS n 
1 50  PRO n 
1 51  LEU n 
1 52  GLN n 
1 53  GLY n 
1 54  ALA n 
1 55  ARG n 
1 56  ILE n 
1 57  ALA n 
1 58  GLY n 
1 59  CYS n 
1 60  LEU n 
1 61  HIS n 
1 62  MET n 
1 63  ALA n 
1 64  ILE n 
1 65  ALA n 
1 66  THR n 
1 67  ALA n 
1 68  VAL n 
1 69  LEU n 
1 70  ILE n 
1 71  GLU n 
1 72  THR n 
1 73  LEU n 
1 74  VAL n 
1 75  ALA n 
1 76  LEU n 
1 77  GLY n 
1 78  ALA n 
1 79  GLU n 
1 80  VAL n 
1 81  ARG n 
1 82  TRP n 
1 83  SER n 
1 84  SER n 
1 85  CYS n 
1 86  ASN n 
1 87  ILE n 
1 88  PHE n 
1 89  SER n 
1 90  THR n 
1 91  GLN n 
1 92  ASP n 
1 93  HIS n 
1 94  ALA n 
1 95  ALA n 
1 96  SER n 
1 97  ALA n 
1 98  ILE n 
1 99  ALA n 
1 100 ALA n 
1 101 LYS n 
1 102 GLY n 
1 103 ILE n 
1 104 PRO n 
1 105 VAL n 
1 106 PHE n 
1 107 ALA n 
1 108 TRP n 
1 109 LYS n 
1 110 GLY n 
1 111 GLU n 
1 112 THR n 
1 113 GLU n 
1 114 GLU n 
1 115 GLU n 
1 116 TYR n 
1 117 TRP n 
1 118 TRP n 
1 119 CYS n 
1 120 VAL n 
1 121 GLU n 
1 122 GLN n 
1 123 THR n 
1 124 LEU n 
1 125 SER n 
1 126 GLY n 
1 127 PRO n 
1 128 ASN n 
1 129 GLY n 
1 130 TRP n 
1 131 THR n 
1 132 PRO n 
1 133 ASN n 
1 134 LEU n 
1 135 LEU n 
1 136 LEU n 
1 137 ASP n 
1 138 ASP n 
1 139 GLY n 
1 140 GLY n 
1 141 ASP n 
1 142 LEU n 
1 143 THR n 
1 144 GLN n 
1 145 VAL n 
1 146 VAL n 
1 147 HIS n 
1 148 GLN n 
1 149 LYS n 
1 150 HIS n 
1 151 PRO n 
1 152 LYS n 
1 153 LEU n 
1 154 LEU n 
1 155 THR n 
1 156 ALA n 
1 157 ILE n 
1 158 LYS n 
1 159 GLY n 
1 160 VAL n 
1 161 SER n 
1 162 GLU n 
1 163 GLU n 
1 164 THR n 
1 165 THR n 
1 166 THR n 
1 167 GLY n 
1 168 VAL n 
1 169 ALA n 
1 170 ARG n 
1 171 LEU n 
1 172 TYR n 
1 173 GLU n 
1 174 MET n 
1 175 ALA n 
1 176 LYS n 
1 177 HIS n 
1 178 GLY n 
1 179 GLN n 
1 180 LEU n 
1 181 LYS n 
1 182 ILE n 
1 183 PRO n 
1 184 ALA n 
1 185 ILE n 
1 186 ASN n 
1 187 VAL n 
1 188 ASN n 
1 189 ASN n 
1 190 ALA n 
1 191 VAL n 
1 192 THR n 
1 193 LYS n 
1 194 SER n 
1 195 LYS n 
1 196 PHE n 
1 197 ASP n 
1 198 ASN n 
1 199 LEU n 
1 200 TYR n 
1 201 GLY n 
1 202 CYS n 
1 203 ARG n 
1 204 GLU n 
1 205 SER n 
1 206 LEU n 
1 207 LEU n 
1 208 ASP n 
1 209 GLY n 
1 210 LEU n 
1 211 LYS n 
1 212 ARG n 
1 213 ALA n 
1 214 THR n 
1 215 ASP n 
1 216 VAL n 
1 217 MET n 
1 218 ILE n 
1 219 ALA n 
1 220 GLY n 
1 221 LYS n 
1 222 VAL n 
1 223 ALA n 
1 224 LEU n 
1 225 ILE n 
1 226 LEU n 
1 227 GLY n 
1 228 TYR n 
1 229 GLY n 
1 230 ASP n 
1 231 VAL n 
1 232 GLY n 
1 233 LYS n 
1 234 GLY n 
1 235 CYS n 
1 236 ALA n 
1 237 GLN n 
1 238 ALA n 
1 239 LEU n 
1 240 ARG n 
1 241 GLY n 
1 242 GLN n 
1 243 GLY n 
1 244 ALA n 
1 245 THR n 
1 246 VAL n 
1 247 LEU n 
1 248 VAL n 
1 249 ALA n 
1 250 GLU n 
1 251 ILE n 
1 252 ASP n 
1 253 PRO n 
1 254 ILE n 
1 255 CYS n 
1 256 ALA n 
1 257 LEU n 
1 258 GLN n 
1 259 ALA n 
1 260 ALA n 
1 261 MET n 
1 262 GLU n 
1 263 GLY n 
1 264 TYR n 
1 265 ARG n 
1 266 VAL n 
1 267 VAL n 
1 268 THR n 
1 269 LEU n 
1 270 ASP n 
1 271 ASP n 
1 272 VAL n 
1 273 ALA n 
1 274 GLU n 
1 275 GLN n 
1 276 VAL n 
1 277 ASP n 
1 278 ILE n 
1 279 VAL n 
1 280 VAL n 
1 281 THR n 
1 282 ALA n 
1 283 THR n 
1 284 GLY n 
1 285 ASN n 
1 286 TYR n 
1 287 HIS n 
1 288 VAL n 
1 289 VAL n 
1 290 THR n 
1 291 HIS n 
1 292 ASP n 
1 293 HIS n 
1 294 MET n 
1 295 LYS n 
1 296 ARG n 
1 297 MET n 
1 298 ARG n 
1 299 ASN n 
1 300 GLN n 
1 301 ALA n 
1 302 ILE n 
1 303 LEU n 
1 304 CYS n 
1 305 ASN n 
1 306 ILE n 
1 307 GLY n 
1 308 HIS n 
1 309 PHE n 
1 310 ASP n 
1 311 SER n 
1 312 GLU n 
1 313 ILE n 
1 314 ASP n 
1 315 ILE n 
1 316 GLN n 
1 317 SER n 
1 318 LEU n 
1 319 LYS n 
1 320 GLN n 
1 321 TYR n 
1 322 GLN n 
1 323 TRP n 
1 324 GLU n 
1 325 ASN n 
1 326 ILE n 
1 327 LYS n 
1 328 PRO n 
1 329 GLN n 
1 330 VAL n 
1 331 ASP n 
1 332 HIS n 
1 333 VAL n 
1 334 ILE n 
1 335 PHE n 
1 336 PRO n 
1 337 ASP n 
1 338 GLY n 
1 339 LYS n 
1 340 ARG n 
1 341 ILE n 
1 342 ILE n 
1 343 ILE n 
1 344 LEU n 
1 345 ALA n 
1 346 GLU n 
1 347 GLY n 
1 348 ARG n 
1 349 LEU n 
1 350 VAL n 
1 351 ASN n 
1 352 LEU n 
1 353 GLY n 
1 354 CYS n 
1 355 ALA n 
1 356 THR n 
1 357 GLY n 
1 358 HIS n 
1 359 PRO n 
1 360 SER n 
1 361 PHE n 
1 362 VAL n 
1 363 MET n 
1 364 SER n 
1 365 ALA n 
1 366 SER n 
1 367 PHE n 
1 368 THR n 
1 369 ASN n 
1 370 GLN n 
1 371 VAL n 
1 372 LEU n 
1 373 ALA n 
1 374 GLN n 
1 375 ILE n 
1 376 GLU n 
1 377 LEU n 
1 378 PHE n 
1 379 GLN n 
1 380 ASN n 
1 381 SER n 
1 382 SER n 
1 383 GLN n 
1 384 TYR n 
1 385 GLN n 
1 386 ASN n 
1 387 GLN n 
1 388 VAL n 
1 389 TYR n 
1 390 VAL n 
1 391 LEU n 
1 392 PRO n 
1 393 LYS n 
1 394 VAL n 
1 395 LEU n 
1 396 ASP n 
1 397 GLU n 
1 398 LYS n 
1 399 VAL n 
1 400 ALA n 
1 401 ARG n 
1 402 LEU n 
1 403 HIS n 
1 404 LEU n 
1 405 GLY n 
1 406 ARG n 
1 407 ILE n 
1 408 GLY n 
1 409 ALA n 
1 410 LYS n 
1 411 LEU n 
1 412 THR n 
1 413 GLN n 
1 414 LEU n 
1 415 SER n 
1 416 ASN n 
1 417 GLU n 
1 418 GLN n 
1 419 ALA n 
1 420 ASP n 
1 421 TYR n 
1 422 ILE n 
1 423 GLY n 
1 424 VAL n 
1 425 ASP n 
1 426 LYS n 
1 427 ASN n 
1 428 GLY n 
1 429 PRO n 
1 430 TYR n 
1 431 LYS n 
1 432 PRO n 
1 433 ASP n 
1 434 HIS n 
1 435 TYR n 
1 436 ARG n 
1 437 TYR n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   437 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ahcY 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Legionella pneumophila' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     446 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                           ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                          ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                        ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                   ? 'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                          ? 'C3 H7 N O2 S'      121.158 
GLN 'L-peptide linking' y GLUTAMINE                         ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                   ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                           ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                         ? 'C6 H10 N3 O2 1'    156.162 
HOH non-polymer         . WATER                             ? 'H2 O'              18.015  
ILE 'L-peptide linking' y ISOLEUCINE                        ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                           ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                            ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                        ? 'C5 H11 N O2 S'     149.211 
NAD non-polymer         . NICOTINAMIDE-ADENINE-DINUCLEOTIDE ? 'C21 H27 N7 O14 P2' 663.425 
PHE 'L-peptide linking' y PHENYLALANINE                     ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                           ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                            ? 'C3 H7 N O3'        105.093 
SO4 non-polymer         . 'SULFATE ION'                     ? 'O4 S -2'           96.063  
THR 'L-peptide linking' y THREONINE                         ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                        ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                          ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                            ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   5   ?   ?   ?   A . n 
A 1 2   GLY 2   6   ?   ?   ?   A . n 
A 1 3   HIS 3   7   ?   ?   ?   A . n 
A 1 4   HIS 4   8   ?   ?   ?   A . n 
A 1 5   HIS 5   9   ?   ?   ?   A . n 
A 1 6   HIS 6   10  ?   ?   ?   A . n 
A 1 7   HIS 7   11  ?   ?   ?   A . n 
A 1 8   HIS 8   12  ?   ?   ?   A . n 
A 1 9   HIS 9   13  ?   ?   ?   A . n 
A 1 10  HIS 10  14  ?   ?   ?   A . n 
A 1 11  GLN 11  15  15  GLN GLN A . n 
A 1 12  ASP 12  16  16  ASP ASP A . n 
A 1 13  TYR 13  17  17  TYR TYR A . n 
A 1 14  LYS 14  18  18  LYS LYS A . n 
A 1 15  VAL 15  19  19  VAL VAL A . n 
A 1 16  ALA 16  20  20  ALA ALA A . n 
A 1 17  GLU 17  21  21  GLU GLU A . n 
A 1 18  ILE 18  22  22  ILE ILE A . n 
A 1 19  SER 19  23  23  SER SER A . n 
A 1 20  LEU 20  24  24  LEU LEU A . n 
A 1 21  ALA 21  25  25  ALA ALA A . n 
A 1 22  ASP 22  26  26  ASP ASP A . n 
A 1 23  TRP 23  27  27  TRP TRP A . n 
A 1 24  GLY 24  28  28  GLY GLY A . n 
A 1 25  ARG 25  29  29  ARG ARG A . n 
A 1 26  LYS 26  30  30  LYS LYS A . n 
A 1 27  GLU 27  31  31  GLU GLU A . n 
A 1 28  ILE 28  32  32  ILE ILE A . n 
A 1 29  ALA 29  33  33  ALA ALA A . n 
A 1 30  ILE 30  34  34  ILE ILE A . n 
A 1 31  ALA 31  35  35  ALA ALA A . n 
A 1 32  GLU 32  36  36  GLU GLU A . n 
A 1 33  THR 33  37  37  THR THR A . n 
A 1 34  GLU 34  38  38  GLU GLU A . n 
A 1 35  MET 35  39  39  MET MET A . n 
A 1 36  PRO 36  40  40  PRO PRO A . n 
A 1 37  GLY 37  41  41  GLY GLY A . n 
A 1 38  LEU 38  42  42  LEU LEU A . n 
A 1 39  MET 39  43  43  MET MET A . n 
A 1 40  ALA 40  44  44  ALA ALA A . n 
A 1 41  LEU 41  45  45  LEU LEU A . n 
A 1 42  ARG 42  46  46  ARG ARG A . n 
A 1 43  GLU 43  47  47  GLU GLU A . n 
A 1 44  GLU 44  48  48  GLU GLU A . n 
A 1 45  PHE 45  49  49  PHE PHE A . n 
A 1 46  SER 46  50  50  SER SER A . n 
A 1 47  ALA 47  51  51  ALA ALA A . n 
A 1 48  LYS 48  52  52  LYS LYS A . n 
A 1 49  LYS 49  53  53  LYS LYS A . n 
A 1 50  PRO 50  54  54  PRO PRO A . n 
A 1 51  LEU 51  55  55  LEU LEU A . n 
A 1 52  GLN 52  56  56  GLN GLN A . n 
A 1 53  GLY 53  57  57  GLY GLY A . n 
A 1 54  ALA 54  58  58  ALA ALA A . n 
A 1 55  ARG 55  59  59  ARG ARG A . n 
A 1 56  ILE 56  60  60  ILE ILE A . n 
A 1 57  ALA 57  61  61  ALA ALA A . n 
A 1 58  GLY 58  62  62  GLY GLY A . n 
A 1 59  CYS 59  63  63  CYS CYS A . n 
A 1 60  LEU 60  64  64  LEU LEU A . n 
A 1 61  HIS 61  65  65  HIS HIS A . n 
A 1 62  MET 62  66  66  MET MET A . n 
A 1 63  ALA 63  67  67  ALA ALA A . n 
A 1 64  ILE 64  68  68  ILE ILE A . n 
A 1 65  ALA 65  69  69  ALA ALA A . n 
A 1 66  THR 66  70  70  THR THR A . n 
A 1 67  ALA 67  71  71  ALA ALA A . n 
A 1 68  VAL 68  72  72  VAL VAL A . n 
A 1 69  LEU 69  73  73  LEU LEU A . n 
A 1 70  ILE 70  74  74  ILE ILE A . n 
A 1 71  GLU 71  75  75  GLU GLU A . n 
A 1 72  THR 72  76  76  THR THR A . n 
A 1 73  LEU 73  77  77  LEU LEU A . n 
A 1 74  VAL 74  78  78  VAL VAL A . n 
A 1 75  ALA 75  79  79  ALA ALA A . n 
A 1 76  LEU 76  80  80  LEU LEU A . n 
A 1 77  GLY 77  81  81  GLY GLY A . n 
A 1 78  ALA 78  82  82  ALA ALA A . n 
A 1 79  GLU 79  83  83  GLU GLU A . n 
A 1 80  VAL 80  84  84  VAL VAL A . n 
A 1 81  ARG 81  85  85  ARG ARG A . n 
A 1 82  TRP 82  86  86  TRP TRP A . n 
A 1 83  SER 83  87  87  SER SER A . n 
A 1 84  SER 84  88  88  SER SER A . n 
A 1 85  CYS 85  89  89  CYS CYS A . n 
A 1 86  ASN 86  90  90  ASN ASN A . n 
A 1 87  ILE 87  91  91  ILE ILE A . n 
A 1 88  PHE 88  92  92  PHE PHE A . n 
A 1 89  SER 89  93  93  SER SER A . n 
A 1 90  THR 90  94  94  THR THR A . n 
A 1 91  GLN 91  95  95  GLN GLN A . n 
A 1 92  ASP 92  96  96  ASP ASP A . n 
A 1 93  HIS 93  97  97  HIS HIS A . n 
A 1 94  ALA 94  98  98  ALA ALA A . n 
A 1 95  ALA 95  99  99  ALA ALA A . n 
A 1 96  SER 96  100 100 SER SER A . n 
A 1 97  ALA 97  101 101 ALA ALA A . n 
A 1 98  ILE 98  102 102 ILE ILE A . n 
A 1 99  ALA 99  103 103 ALA ALA A . n 
A 1 100 ALA 100 104 104 ALA ALA A . n 
A 1 101 LYS 101 105 105 LYS LYS A . n 
A 1 102 GLY 102 106 106 GLY GLY A . n 
A 1 103 ILE 103 107 107 ILE ILE A . n 
A 1 104 PRO 104 108 108 PRO PRO A . n 
A 1 105 VAL 105 109 109 VAL VAL A . n 
A 1 106 PHE 106 110 110 PHE PHE A . n 
A 1 107 ALA 107 111 111 ALA ALA A . n 
A 1 108 TRP 108 112 112 TRP TRP A . n 
A 1 109 LYS 109 113 113 LYS LYS A . n 
A 1 110 GLY 110 114 114 GLY GLY A . n 
A 1 111 GLU 111 115 115 GLU GLU A . n 
A 1 112 THR 112 116 116 THR THR A . n 
A 1 113 GLU 113 117 117 GLU GLU A . n 
A 1 114 GLU 114 118 118 GLU GLU A . n 
A 1 115 GLU 115 119 119 GLU GLU A . n 
A 1 116 TYR 116 120 120 TYR TYR A . n 
A 1 117 TRP 117 121 121 TRP TRP A . n 
A 1 118 TRP 118 122 122 TRP TRP A . n 
A 1 119 CYS 119 123 123 CYS CYS A . n 
A 1 120 VAL 120 124 124 VAL VAL A . n 
A 1 121 GLU 121 125 125 GLU GLU A . n 
A 1 122 GLN 122 126 126 GLN GLN A . n 
A 1 123 THR 123 127 127 THR THR A . n 
A 1 124 LEU 124 128 128 LEU LEU A . n 
A 1 125 SER 125 129 129 SER SER A . n 
A 1 126 GLY 126 130 130 GLY GLY A . n 
A 1 127 PRO 127 131 131 PRO PRO A . n 
A 1 128 ASN 128 132 132 ASN ASN A . n 
A 1 129 GLY 129 133 133 GLY GLY A . n 
A 1 130 TRP 130 134 134 TRP TRP A . n 
A 1 131 THR 131 135 135 THR THR A . n 
A 1 132 PRO 132 136 136 PRO PRO A . n 
A 1 133 ASN 133 137 137 ASN ASN A . n 
A 1 134 LEU 134 138 138 LEU LEU A . n 
A 1 135 LEU 135 139 139 LEU LEU A . n 
A 1 136 LEU 136 140 140 LEU LEU A . n 
A 1 137 ASP 137 141 141 ASP ASP A . n 
A 1 138 ASP 138 142 142 ASP ASP A . n 
A 1 139 GLY 139 143 143 GLY GLY A . n 
A 1 140 GLY 140 144 144 GLY GLY A . n 
A 1 141 ASP 141 145 145 ASP ASP A . n 
A 1 142 LEU 142 146 146 LEU LEU A . n 
A 1 143 THR 143 147 147 THR THR A . n 
A 1 144 GLN 144 148 148 GLN GLN A . n 
A 1 145 VAL 145 149 149 VAL VAL A . n 
A 1 146 VAL 146 150 150 VAL VAL A . n 
A 1 147 HIS 147 151 151 HIS HIS A . n 
A 1 148 GLN 148 152 152 GLN GLN A . n 
A 1 149 LYS 149 153 153 LYS LYS A . n 
A 1 150 HIS 150 154 154 HIS HIS A . n 
A 1 151 PRO 151 155 155 PRO PRO A . n 
A 1 152 LYS 152 156 156 LYS LYS A . n 
A 1 153 LEU 153 157 157 LEU LEU A . n 
A 1 154 LEU 154 158 158 LEU LEU A . n 
A 1 155 THR 155 159 159 THR THR A . n 
A 1 156 ALA 156 160 160 ALA ALA A . n 
A 1 157 ILE 157 161 161 ILE ILE A . n 
A 1 158 LYS 158 162 162 LYS LYS A . n 
A 1 159 GLY 159 163 163 GLY GLY A . n 
A 1 160 VAL 160 164 164 VAL VAL A . n 
A 1 161 SER 161 165 165 SER SER A . n 
A 1 162 GLU 162 166 166 GLU GLU A . n 
A 1 163 GLU 163 167 167 GLU GLU A . n 
A 1 164 THR 164 168 168 THR THR A . n 
A 1 165 THR 165 169 169 THR THR A . n 
A 1 166 THR 166 170 170 THR THR A . n 
A 1 167 GLY 167 171 171 GLY GLY A . n 
A 1 168 VAL 168 172 172 VAL VAL A . n 
A 1 169 ALA 169 173 173 ALA ALA A . n 
A 1 170 ARG 170 174 174 ARG ARG A . n 
A 1 171 LEU 171 175 175 LEU LEU A . n 
A 1 172 TYR 172 176 176 TYR TYR A . n 
A 1 173 GLU 173 177 177 GLU GLU A . n 
A 1 174 MET 174 178 178 MET MET A . n 
A 1 175 ALA 175 179 179 ALA ALA A . n 
A 1 176 LYS 176 180 180 LYS LYS A . n 
A 1 177 HIS 177 181 181 HIS HIS A . n 
A 1 178 GLY 178 182 182 GLY GLY A . n 
A 1 179 GLN 179 183 183 GLN GLN A . n 
A 1 180 LEU 180 184 184 LEU LEU A . n 
A 1 181 LYS 181 185 185 LYS LYS A . n 
A 1 182 ILE 182 186 186 ILE ILE A . n 
A 1 183 PRO 183 187 187 PRO PRO A . n 
A 1 184 ALA 184 188 188 ALA ALA A . n 
A 1 185 ILE 185 189 189 ILE ILE A . n 
A 1 186 ASN 186 190 190 ASN ASN A . n 
A 1 187 VAL 187 191 191 VAL VAL A . n 
A 1 188 ASN 188 192 192 ASN ASN A . n 
A 1 189 ASN 189 193 193 ASN ASN A . n 
A 1 190 ALA 190 194 194 ALA ALA A . n 
A 1 191 VAL 191 195 195 VAL VAL A . n 
A 1 192 THR 192 196 196 THR THR A . n 
A 1 193 LYS 193 197 197 LYS LYS A . n 
A 1 194 SER 194 198 198 SER SER A . n 
A 1 195 LYS 195 199 199 LYS LYS A . n 
A 1 196 PHE 196 200 200 PHE PHE A . n 
A 1 197 ASP 197 201 201 ASP ASP A . n 
A 1 198 ASN 198 202 202 ASN ASN A . n 
A 1 199 LEU 199 203 203 LEU LEU A . n 
A 1 200 TYR 200 204 204 TYR TYR A . n 
A 1 201 GLY 201 205 205 GLY GLY A . n 
A 1 202 CYS 202 206 206 CYS CYS A . n 
A 1 203 ARG 203 207 207 ARG ARG A . n 
A 1 204 GLU 204 208 208 GLU GLU A . n 
A 1 205 SER 205 209 209 SER SER A . n 
A 1 206 LEU 206 210 210 LEU LEU A . n 
A 1 207 LEU 207 211 211 LEU LEU A . n 
A 1 208 ASP 208 212 212 ASP ASP A . n 
A 1 209 GLY 209 213 213 GLY GLY A . n 
A 1 210 LEU 210 214 214 LEU LEU A . n 
A 1 211 LYS 211 215 215 LYS LYS A . n 
A 1 212 ARG 212 216 216 ARG ARG A . n 
A 1 213 ALA 213 217 217 ALA ALA A . n 
A 1 214 THR 214 218 218 THR THR A . n 
A 1 215 ASP 215 219 219 ASP ASP A . n 
A 1 216 VAL 216 220 220 VAL VAL A . n 
A 1 217 MET 217 221 221 MET MET A . n 
A 1 218 ILE 218 222 222 ILE ILE A . n 
A 1 219 ALA 219 223 223 ALA ALA A . n 
A 1 220 GLY 220 224 224 GLY GLY A . n 
A 1 221 LYS 221 225 225 LYS LYS A . n 
A 1 222 VAL 222 226 226 VAL VAL A . n 
A 1 223 ALA 223 227 227 ALA ALA A . n 
A 1 224 LEU 224 228 228 LEU LEU A . n 
A 1 225 ILE 225 229 229 ILE ILE A . n 
A 1 226 LEU 226 230 230 LEU LEU A . n 
A 1 227 GLY 227 231 231 GLY GLY A . n 
A 1 228 TYR 228 232 232 TYR TYR A . n 
A 1 229 GLY 229 233 233 GLY GLY A . n 
A 1 230 ASP 230 234 234 ASP ASP A . n 
A 1 231 VAL 231 235 235 VAL VAL A . n 
A 1 232 GLY 232 236 236 GLY GLY A . n 
A 1 233 LYS 233 237 237 LYS LYS A . n 
A 1 234 GLY 234 238 238 GLY GLY A . n 
A 1 235 CYS 235 239 239 CYS CYS A . n 
A 1 236 ALA 236 240 240 ALA ALA A . n 
A 1 237 GLN 237 241 241 GLN GLN A . n 
A 1 238 ALA 238 242 242 ALA ALA A . n 
A 1 239 LEU 239 243 243 LEU LEU A . n 
A 1 240 ARG 240 244 244 ARG ARG A . n 
A 1 241 GLY 241 245 245 GLY GLY A . n 
A 1 242 GLN 242 246 246 GLN GLN A . n 
A 1 243 GLY 243 247 247 GLY GLY A . n 
A 1 244 ALA 244 248 248 ALA ALA A . n 
A 1 245 THR 245 249 249 THR THR A . n 
A 1 246 VAL 246 250 250 VAL VAL A . n 
A 1 247 LEU 247 251 251 LEU LEU A . n 
A 1 248 VAL 248 252 252 VAL VAL A . n 
A 1 249 ALA 249 253 253 ALA ALA A . n 
A 1 250 GLU 250 254 254 GLU GLU A . n 
A 1 251 ILE 251 255 255 ILE ILE A . n 
A 1 252 ASP 252 256 256 ASP ASP A . n 
A 1 253 PRO 253 257 257 PRO PRO A . n 
A 1 254 ILE 254 258 258 ILE ILE A . n 
A 1 255 CYS 255 259 259 CYS CYS A . n 
A 1 256 ALA 256 260 260 ALA ALA A . n 
A 1 257 LEU 257 261 261 LEU LEU A . n 
A 1 258 GLN 258 262 262 GLN GLN A . n 
A 1 259 ALA 259 263 263 ALA ALA A . n 
A 1 260 ALA 260 264 264 ALA ALA A . n 
A 1 261 MET 261 265 265 MET MET A . n 
A 1 262 GLU 262 266 266 GLU GLU A . n 
A 1 263 GLY 263 267 267 GLY GLY A . n 
A 1 264 TYR 264 268 268 TYR TYR A . n 
A 1 265 ARG 265 269 269 ARG ARG A . n 
A 1 266 VAL 266 270 270 VAL VAL A . n 
A 1 267 VAL 267 271 271 VAL VAL A . n 
A 1 268 THR 268 272 272 THR THR A . n 
A 1 269 LEU 269 273 273 LEU LEU A . n 
A 1 270 ASP 270 274 274 ASP ASP A . n 
A 1 271 ASP 271 275 275 ASP ASP A . n 
A 1 272 VAL 272 276 276 VAL VAL A . n 
A 1 273 ALA 273 277 277 ALA ALA A . n 
A 1 274 GLU 274 278 278 GLU GLU A . n 
A 1 275 GLN 275 279 279 GLN GLN A . n 
A 1 276 VAL 276 280 280 VAL VAL A . n 
A 1 277 ASP 277 281 281 ASP ASP A . n 
A 1 278 ILE 278 282 282 ILE ILE A . n 
A 1 279 VAL 279 283 283 VAL VAL A . n 
A 1 280 VAL 280 284 284 VAL VAL A . n 
A 1 281 THR 281 285 285 THR THR A . n 
A 1 282 ALA 282 286 286 ALA ALA A . n 
A 1 283 THR 283 287 287 THR THR A . n 
A 1 284 GLY 284 288 288 GLY GLY A . n 
A 1 285 ASN 285 289 289 ASN ASN A . n 
A 1 286 TYR 286 290 290 TYR TYR A . n 
A 1 287 HIS 287 291 291 HIS HIS A . n 
A 1 288 VAL 288 292 292 VAL VAL A . n 
A 1 289 VAL 289 293 293 VAL VAL A . n 
A 1 290 THR 290 294 294 THR THR A . n 
A 1 291 HIS 291 295 295 HIS HIS A . n 
A 1 292 ASP 292 296 296 ASP ASP A . n 
A 1 293 HIS 293 297 297 HIS HIS A . n 
A 1 294 MET 294 298 298 MET MET A . n 
A 1 295 LYS 295 299 299 LYS LYS A . n 
A 1 296 ARG 296 300 300 ARG ARG A . n 
A 1 297 MET 297 301 301 MET MET A . n 
A 1 298 ARG 298 302 302 ARG ARG A . n 
A 1 299 ASN 299 303 303 ASN ASN A . n 
A 1 300 GLN 300 304 304 GLN GLN A . n 
A 1 301 ALA 301 305 305 ALA ALA A . n 
A 1 302 ILE 302 306 306 ILE ILE A . n 
A 1 303 LEU 303 307 307 LEU LEU A . n 
A 1 304 CYS 304 308 308 CYS CYS A . n 
A 1 305 ASN 305 309 309 ASN ASN A . n 
A 1 306 ILE 306 310 310 ILE ILE A . n 
A 1 307 GLY 307 311 311 GLY GLY A . n 
A 1 308 HIS 308 312 312 HIS HIS A . n 
A 1 309 PHE 309 313 313 PHE PHE A . n 
A 1 310 ASP 310 314 314 ASP ASP A . n 
A 1 311 SER 311 315 315 SER SER A . n 
A 1 312 GLU 312 316 316 GLU GLU A . n 
A 1 313 ILE 313 317 317 ILE ILE A . n 
A 1 314 ASP 314 318 318 ASP ASP A . n 
A 1 315 ILE 315 319 319 ILE ILE A . n 
A 1 316 GLN 316 320 320 GLN GLN A . n 
A 1 317 SER 317 321 321 SER SER A . n 
A 1 318 LEU 318 322 322 LEU LEU A . n 
A 1 319 LYS 319 323 323 LYS LYS A . n 
A 1 320 GLN 320 324 324 GLN GLN A . n 
A 1 321 TYR 321 325 325 TYR TYR A . n 
A 1 322 GLN 322 326 326 GLN GLN A . n 
A 1 323 TRP 323 327 327 TRP TRP A . n 
A 1 324 GLU 324 328 328 GLU GLU A . n 
A 1 325 ASN 325 329 329 ASN ASN A . n 
A 1 326 ILE 326 330 330 ILE ILE A . n 
A 1 327 LYS 327 331 331 LYS LYS A . n 
A 1 328 PRO 328 332 332 PRO PRO A . n 
A 1 329 GLN 329 333 333 GLN GLN A . n 
A 1 330 VAL 330 334 334 VAL VAL A . n 
A 1 331 ASP 331 335 335 ASP ASP A . n 
A 1 332 HIS 332 336 336 HIS HIS A . n 
A 1 333 VAL 333 337 337 VAL VAL A . n 
A 1 334 ILE 334 338 338 ILE ILE A . n 
A 1 335 PHE 335 339 339 PHE PHE A . n 
A 1 336 PRO 336 340 340 PRO PRO A . n 
A 1 337 ASP 337 341 341 ASP ASP A . n 
A 1 338 GLY 338 342 342 GLY GLY A . n 
A 1 339 LYS 339 343 343 LYS LYS A . n 
A 1 340 ARG 340 344 344 ARG ARG A . n 
A 1 341 ILE 341 345 345 ILE ILE A . n 
A 1 342 ILE 342 346 346 ILE ILE A . n 
A 1 343 ILE 343 347 347 ILE ILE A . n 
A 1 344 LEU 344 348 348 LEU LEU A . n 
A 1 345 ALA 345 349 349 ALA ALA A . n 
A 1 346 GLU 346 350 350 GLU GLU A . n 
A 1 347 GLY 347 351 351 GLY GLY A . n 
A 1 348 ARG 348 352 352 ARG ARG A . n 
A 1 349 LEU 349 353 353 LEU LEU A . n 
A 1 350 VAL 350 354 354 VAL VAL A . n 
A 1 351 ASN 351 355 355 ASN ASN A . n 
A 1 352 LEU 352 356 356 LEU LEU A . n 
A 1 353 GLY 353 357 357 GLY GLY A . n 
A 1 354 CYS 354 358 358 CYS CYS A . n 
A 1 355 ALA 355 359 359 ALA ALA A . n 
A 1 356 THR 356 360 360 THR THR A . n 
A 1 357 GLY 357 361 361 GLY GLY A . n 
A 1 358 HIS 358 362 362 HIS HIS A . n 
A 1 359 PRO 359 363 363 PRO PRO A . n 
A 1 360 SER 360 364 364 SER SER A . n 
A 1 361 PHE 361 365 365 PHE PHE A . n 
A 1 362 VAL 362 366 366 VAL VAL A . n 
A 1 363 MET 363 367 367 MET MET A . n 
A 1 364 SER 364 368 368 SER SER A . n 
A 1 365 ALA 365 369 369 ALA ALA A . n 
A 1 366 SER 366 370 370 SER SER A . n 
A 1 367 PHE 367 371 371 PHE PHE A . n 
A 1 368 THR 368 372 372 THR THR A . n 
A 1 369 ASN 369 373 373 ASN ASN A . n 
A 1 370 GLN 370 374 374 GLN GLN A . n 
A 1 371 VAL 371 375 375 VAL VAL A . n 
A 1 372 LEU 372 376 376 LEU LEU A . n 
A 1 373 ALA 373 377 377 ALA ALA A . n 
A 1 374 GLN 374 378 378 GLN GLN A . n 
A 1 375 ILE 375 379 379 ILE ILE A . n 
A 1 376 GLU 376 380 380 GLU GLU A . n 
A 1 377 LEU 377 381 381 LEU LEU A . n 
A 1 378 PHE 378 382 382 PHE PHE A . n 
A 1 379 GLN 379 383 383 GLN GLN A . n 
A 1 380 ASN 380 384 384 ASN ASN A . n 
A 1 381 SER 381 385 385 SER SER A . n 
A 1 382 SER 382 386 386 SER SER A . n 
A 1 383 GLN 383 387 387 GLN GLN A . n 
A 1 384 TYR 384 388 388 TYR TYR A . n 
A 1 385 GLN 385 389 389 GLN GLN A . n 
A 1 386 ASN 386 390 390 ASN ASN A . n 
A 1 387 GLN 387 391 391 GLN GLN A . n 
A 1 388 VAL 388 392 392 VAL VAL A . n 
A 1 389 TYR 389 393 393 TYR TYR A . n 
A 1 390 VAL 390 394 394 VAL VAL A . n 
A 1 391 LEU 391 395 395 LEU LEU A . n 
A 1 392 PRO 392 396 396 PRO PRO A . n 
A 1 393 LYS 393 397 397 LYS LYS A . n 
A 1 394 VAL 394 398 398 VAL VAL A . n 
A 1 395 LEU 395 399 399 LEU LEU A . n 
A 1 396 ASP 396 400 400 ASP ASP A . n 
A 1 397 GLU 397 401 401 GLU GLU A . n 
A 1 398 LYS 398 402 402 LYS LYS A . n 
A 1 399 VAL 399 403 403 VAL VAL A . n 
A 1 400 ALA 400 404 404 ALA ALA A . n 
A 1 401 ARG 401 405 405 ARG ARG A . n 
A 1 402 LEU 402 406 406 LEU LEU A . n 
A 1 403 HIS 403 407 407 HIS HIS A . n 
A 1 404 LEU 404 408 408 LEU LEU A . n 
A 1 405 GLY 405 409 409 GLY GLY A . n 
A 1 406 ARG 406 410 410 ARG ARG A . n 
A 1 407 ILE 407 411 411 ILE ILE A . n 
A 1 408 GLY 408 412 412 GLY GLY A . n 
A 1 409 ALA 409 413 413 ALA ALA A . n 
A 1 410 LYS 410 414 414 LYS LYS A . n 
A 1 411 LEU 411 415 415 LEU LEU A . n 
A 1 412 THR 412 416 416 THR THR A . n 
A 1 413 GLN 413 417 417 GLN GLN A . n 
A 1 414 LEU 414 418 418 LEU LEU A . n 
A 1 415 SER 415 419 419 SER SER A . n 
A 1 416 ASN 416 420 420 ASN ASN A . n 
A 1 417 GLU 417 421 421 GLU GLU A . n 
A 1 418 GLN 418 422 422 GLN GLN A . n 
A 1 419 ALA 419 423 423 ALA ALA A . n 
A 1 420 ASP 420 424 424 ASP ASP A . n 
A 1 421 TYR 421 425 425 TYR TYR A . n 
A 1 422 ILE 422 426 426 ILE ILE A . n 
A 1 423 GLY 423 427 427 GLY GLY A . n 
A 1 424 VAL 424 428 428 VAL VAL A . n 
A 1 425 ASP 425 429 429 ASP ASP A . n 
A 1 426 LYS 426 430 430 LYS LYS A . n 
A 1 427 ASN 427 431 431 ASN ASN A . n 
A 1 428 GLY 428 432 432 GLY GLY A . n 
A 1 429 PRO 429 433 433 PRO PRO A . n 
A 1 430 TYR 430 434 434 TYR TYR A . n 
A 1 431 LYS 431 435 435 LYS LYS A . n 
A 1 432 PRO 432 436 436 PRO PRO A . n 
A 1 433 ASP 433 437 437 ASP ASP A . n 
A 1 434 HIS 434 438 438 HIS HIS A . n 
A 1 435 TYR 435 439 439 TYR TYR A . n 
A 1 436 ARG 436 440 440 ARG ARG A . n 
A 1 437 TYR 437 441 441 TYR TYR A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        NAD 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   NAD 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 NAD 1   501 501 NAD NAD A . 
C 3 SO4 1   502 1   SO4 SO4 A . 
D 4 HOH 1   601 92  HOH HOH A . 
D 4 HOH 2   602 86  HOH HOH A . 
D 4 HOH 3   603 29  HOH HOH A . 
D 4 HOH 4   604 57  HOH HOH A . 
D 4 HOH 5   605 106 HOH HOH A . 
D 4 HOH 6   606 78  HOH HOH A . 
D 4 HOH 7   607 27  HOH HOH A . 
D 4 HOH 8   608 121 HOH HOH A . 
D 4 HOH 9   609 19  HOH HOH A . 
D 4 HOH 10  610 80  HOH HOH A . 
D 4 HOH 11  611 24  HOH HOH A . 
D 4 HOH 12  612 118 HOH HOH A . 
D 4 HOH 13  613 20  HOH HOH A . 
D 4 HOH 14  614 23  HOH HOH A . 
D 4 HOH 15  615 62  HOH HOH A . 
D 4 HOH 16  616 33  HOH HOH A . 
D 4 HOH 17  617 18  HOH HOH A . 
D 4 HOH 18  618 5   HOH HOH A . 
D 4 HOH 19  619 44  HOH HOH A . 
D 4 HOH 20  620 73  HOH HOH A . 
D 4 HOH 21  621 65  HOH HOH A . 
D 4 HOH 22  622 49  HOH HOH A . 
D 4 HOH 23  623 97  HOH HOH A . 
D 4 HOH 24  624 2   HOH HOH A . 
D 4 HOH 25  625 58  HOH HOH A . 
D 4 HOH 26  626 39  HOH HOH A . 
D 4 HOH 27  627 103 HOH HOH A . 
D 4 HOH 28  628 71  HOH HOH A . 
D 4 HOH 29  629 11  HOH HOH A . 
D 4 HOH 30  630 98  HOH HOH A . 
D 4 HOH 31  631 48  HOH HOH A . 
D 4 HOH 32  632 14  HOH HOH A . 
D 4 HOH 33  633 12  HOH HOH A . 
D 4 HOH 34  634 74  HOH HOH A . 
D 4 HOH 35  635 7   HOH HOH A . 
D 4 HOH 36  636 16  HOH HOH A . 
D 4 HOH 37  637 41  HOH HOH A . 
D 4 HOH 38  638 34  HOH HOH A . 
D 4 HOH 39  639 4   HOH HOH A . 
D 4 HOH 40  640 42  HOH HOH A . 
D 4 HOH 41  641 60  HOH HOH A . 
D 4 HOH 42  642 8   HOH HOH A . 
D 4 HOH 43  643 15  HOH HOH A . 
D 4 HOH 44  644 70  HOH HOH A . 
D 4 HOH 45  645 1   HOH HOH A . 
D 4 HOH 46  646 6   HOH HOH A . 
D 4 HOH 47  647 31  HOH HOH A . 
D 4 HOH 48  648 115 HOH HOH A . 
D 4 HOH 49  649 59  HOH HOH A . 
D 4 HOH 50  650 81  HOH HOH A . 
D 4 HOH 51  651 30  HOH HOH A . 
D 4 HOH 52  652 72  HOH HOH A . 
D 4 HOH 53  653 53  HOH HOH A . 
D 4 HOH 54  654 50  HOH HOH A . 
D 4 HOH 55  655 9   HOH HOH A . 
D 4 HOH 56  656 55  HOH HOH A . 
D 4 HOH 57  657 13  HOH HOH A . 
D 4 HOH 58  658 46  HOH HOH A . 
D 4 HOH 59  659 40  HOH HOH A . 
D 4 HOH 60  660 37  HOH HOH A . 
D 4 HOH 61  661 88  HOH HOH A . 
D 4 HOH 62  662 99  HOH HOH A . 
D 4 HOH 63  663 3   HOH HOH A . 
D 4 HOH 64  664 10  HOH HOH A . 
D 4 HOH 65  665 35  HOH HOH A . 
D 4 HOH 66  666 104 HOH HOH A . 
D 4 HOH 67  667 21  HOH HOH A . 
D 4 HOH 68  668 25  HOH HOH A . 
D 4 HOH 69  669 61  HOH HOH A . 
D 4 HOH 70  670 22  HOH HOH A . 
D 4 HOH 71  671 79  HOH HOH A . 
D 4 HOH 72  672 28  HOH HOH A . 
D 4 HOH 73  673 91  HOH HOH A . 
D 4 HOH 74  674 110 HOH HOH A . 
D 4 HOH 75  675 63  HOH HOH A . 
D 4 HOH 76  676 36  HOH HOH A . 
D 4 HOH 77  677 17  HOH HOH A . 
D 4 HOH 78  678 111 HOH HOH A . 
D 4 HOH 79  679 38  HOH HOH A . 
D 4 HOH 80  680 85  HOH HOH A . 
D 4 HOH 81  681 105 HOH HOH A . 
D 4 HOH 82  682 45  HOH HOH A . 
D 4 HOH 83  683 100 HOH HOH A . 
D 4 HOH 84  684 64  HOH HOH A . 
D 4 HOH 85  685 43  HOH HOH A . 
D 4 HOH 86  686 122 HOH HOH A . 
D 4 HOH 87  687 52  HOH HOH A . 
D 4 HOH 88  688 47  HOH HOH A . 
D 4 HOH 89  689 68  HOH HOH A . 
D 4 HOH 90  690 114 HOH HOH A . 
D 4 HOH 91  691 102 HOH HOH A . 
D 4 HOH 92  692 82  HOH HOH A . 
D 4 HOH 93  693 69  HOH HOH A . 
D 4 HOH 94  694 32  HOH HOH A . 
D 4 HOH 95  695 77  HOH HOH A . 
D 4 HOH 96  696 113 HOH HOH A . 
D 4 HOH 97  697 119 HOH HOH A . 
D 4 HOH 98  698 75  HOH HOH A . 
D 4 HOH 99  699 107 HOH HOH A . 
D 4 HOH 100 700 56  HOH HOH A . 
D 4 HOH 101 701 26  HOH HOH A . 
D 4 HOH 102 702 95  HOH HOH A . 
D 4 HOH 103 703 83  HOH HOH A . 
D 4 HOH 104 704 66  HOH HOH A . 
D 4 HOH 105 705 87  HOH HOH A . 
D 4 HOH 106 706 89  HOH HOH A . 
D 4 HOH 107 707 123 HOH HOH A . 
D 4 HOH 108 708 67  HOH HOH A . 
D 4 HOH 109 709 84  HOH HOH A . 
D 4 HOH 110 710 116 HOH HOH A . 
D 4 HOH 111 711 101 HOH HOH A . 
D 4 HOH 112 712 76  HOH HOH A . 
D 4 HOH 113 713 108 HOH HOH A . 
D 4 HOH 114 714 94  HOH HOH A . 
D 4 HOH 115 715 120 HOH HOH A . 
D 4 HOH 116 716 109 HOH HOH A . 
D 4 HOH 117 717 54  HOH HOH A . 
D 4 HOH 118 718 117 HOH HOH A . 
D 4 HOH 119 719 112 HOH HOH A . 
D 4 HOH 120 720 93  HOH HOH A . 
D 4 HOH 121 721 51  HOH HOH A . 
D 4 HOH 122 722 90  HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? 'data scaling'    ? ? ? ? ? ? ? ? ? ? ? HKL-3000    ? ? ? 7.21 1 
? refinement        ? ? ? ? ? ? ? ? ? ? ? PHENIX      ? ? ? 1.13 2 
? 'data extraction' ? ? ? ? ? ? ? ? ? ? ? PDB_EXTRACT ? ? ? 3.27 3 
? 'data reduction'  ? ? ? ? ? ? ? ? ? ? ? HKL-3000    ? ? ? 7.21 4 
? phasing           ? ? ? ? ? ? ? ? ? ? ? PHASER      ? ? ? 2.70 5 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8WZ8 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     131.600 
_cell.length_a_esd                 ? 
_cell.length_b                     131.600 
_cell.length_b_esd                 ? 
_cell.length_c                     115.886 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        12 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8WZ8 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                180 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 62 2 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8WZ8 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.08 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          60.02 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;2.0 M Ammonium sulfate
0.1 M Bis-Tris pH 5.5
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            289 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-09-16 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    Si111 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97853 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL18U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97853 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL18U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          38.31 
_reflns.entry_id                                       8WZ8 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.583 
_reflns.d_resolution_low                               50 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     19107 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           97.64 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                38.31 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          22.76 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.992 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.583 
_reflns_shell.d_res_low                                     2.68 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             18631 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.938 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.201 
_refine.aniso_B[1][2]                            -0.101 
_refine.aniso_B[1][3]                            -0.000 
_refine.aniso_B[2][2]                            -0.201 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            0.652 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               46.277 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.921 
_refine.correlation_coeff_Fo_to_Fc_free          0.893 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8WZ8 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.583 
_refine.ls_d_res_low                             43.524 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     18665 
_refine.ls_number_reflns_R_free                  969 
_refine.ls_number_reflns_R_work                  17696 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    97.631 
_refine.ls_percent_reflns_R_free                 5.192 
_refine.ls_R_factor_all                          0.224 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2716 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2215 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      Q5ZTY7 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.560 
_refine.pdbx_overall_ESU_R_Free                  0.319 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.583 
_refine_hist.d_res_low                        43.524 
_refine_hist.number_atoms_solvent             122 
_refine_hist.number_atoms_total               3471 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3300 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         49 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.010  0.012  3415 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.016  3249 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.487  1.643  4642 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.730  1.573  7473 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.434  5.000  426  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 5.747  5.000  17   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.339  5.000  1    ? r_dihedral_angle_other_2_deg   ? ? 
'X-RAY DIFFRACTION' ? 19.590 10.000 579  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.723 10.000 149  ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.067  0.200  530  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.004  0.020  3966 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.003  0.020  751  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.214  0.200  774  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.232  0.200  3317 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.187  0.200  1710 ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.082  0.200  1938 ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.189  0.200  153  ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.118  0.200  4    ? r_symmetry_xyhbond_nbd_other   ? ? 
'X-RAY DIFFRACTION' ? 0.101  0.200  41   ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.207  0.200  238  ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.161  0.200  36   ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 5.043  4.845  1707 ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 5.041  4.845  1707 ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 7.182  8.673  2132 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 7.181  8.672  2133 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 5.872  5.047  1708 ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 5.871  5.047  1705 ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 8.384  9.142  2510 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 8.382  9.141  2505 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 10.066 48.132 3963 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 10.062 47.935 3941 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.583  2.650  1361 . 63 1128 87.5092  . 0.287 . . 0.279 . . . . . 0.238 . 20 . 0.951 0.888 0.455 
'X-RAY DIFFRACTION' 2.650  2.722  1349 . 81 1205 95.3299  . 0.267 . . 0.262 . . . . . 0.226 . 20 . 0.955 0.932 0.342 
'X-RAY DIFFRACTION' 2.722  2.801  1304 . 67 1217 98.4663  . 0.284 . . 0.276 . . . . . 0.232 . 20 . 0.949 0.884 0.443 
'X-RAY DIFFRACTION' 2.801  2.887  1265 . 69 1183 98.9723  . 0.266 . . 0.264 . . . . . 0.221 . 20 . 0.954 0.936 0.299 
'X-RAY DIFFRACTION' 2.887  2.981  1240 . 65 1164 99.1129  . 0.267 . . 0.263 . . . . . 0.223 . 20 . 0.956 0.917 0.342 
'X-RAY DIFFRACTION' 2.981  3.085  1193 . 66 1112 98.7427  . 0.237 . . 0.236 . . . . . 0.205 . 20 . 0.964 0.956 0.254 
'X-RAY DIFFRACTION' 3.085  3.201  1162 . 57 1087 98.4509  . 0.257 . . 0.255 . . . . . 0.225 . 20 . 0.959 0.952 0.282 
'X-RAY DIFFRACTION' 3.201  3.331  1113 . 47 1051 98.6523  . 0.235 . . 0.233 . . . . . 0.216 . 20 . 0.965 0.948 0.272 
'X-RAY DIFFRACTION' 3.331  3.478  1069 . 55 991  97.8485  . 0.217 . . 0.211 . . . . . 0.193 . 20 . 0.971 0.931 0.332 
'X-RAY DIFFRACTION' 3.478  3.647  1043 . 48 963  96.9319  . 0.216 . . 0.213 . . . . . 0.199 . 20 . 0.971 0.947 0.294 
'X-RAY DIFFRACTION' 3.647  3.842  977  . 36 914  97.2364  . 0.219 . . 0.217 . . . . . 0.213 . 20 . 0.969 0.947 0.256 
'X-RAY DIFFRACTION' 3.842  4.074  942  . 51 872  97.9830  . 0.189 . . 0.186 . . . . . 0.192 . 20 . 0.977 0.965 0.240 
'X-RAY DIFFRACTION' 4.074  4.352  877  . 50 817  98.8597  . 0.180 . . 0.179 . . . . . 0.192 . 20 . 0.981 0.976 0.188 
'X-RAY DIFFRACTION' 4.352  4.697  834  . 45 786  99.6403  . 0.182 . . 0.181 . . . . . 0.207 . 20 . 0.982 0.974 0.197 
'X-RAY DIFFRACTION' 4.697  5.139  765  . 42 722  99.8693  . 0.188 . . 0.186 . . . . . 0.210 . 20 . 0.978 0.970 0.219 
'X-RAY DIFFRACTION' 5.139  5.736  709  . 33 676  100.0000 . 0.195 . . 0.192 . . . . . 0.222 . 20 . 0.976 0.961 0.249 
'X-RAY DIFFRACTION' 5.736  6.604  625  . 32 593  100.0000 . 0.219 . . 0.212 . . . . . 0.240 . 20 . 0.969 0.919 0.353 
'X-RAY DIFFRACTION' 6.604  8.042  547  . 26 521  100.0000 . 0.197 . . 0.200 . . . . . 0.234 . 20 . 0.972 0.989 0.154 
'X-RAY DIFFRACTION' 8.042  11.184 445  . 22 421  99.5506  . 0.187 . . 0.182 . . . . . 0.207 . 20 . 0.985 0.957 0.310 
'X-RAY DIFFRACTION' 11.184 43.524 291  . 14 273  98.6254  . 0.419 . . 0.423 . . . . . 0.590 . 20 . 0.857 0.898 0.346 
# 
_struct.entry_id                     8WZ8 
_struct.title                        
'The crystal structure of Legionella pneumophila adenosylhomocysteinase Lpg2021(T67A,Q69A) complex with NAD' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8WZ8 
_struct_keywords.text            'Legionella pneumophila, SAH hydrolase, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A2S6F4T2_LEGPN 
_struct_ref.pdbx_db_accession          A0A2S6F4T2 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;QDYKVAEISLADWGRKEIAIAETEMPGLMALREEFSAKKPLQGARIAGCLHMTIQTAVLIETLVALGAEVRWSSCNIFST
QDHAASAIAAKGIPVFAWKGETEEEYWWCVEQTLSGPNGWTPNLLLDDGGDLTQVVHQKHPKLLTAIKGVSEETTTGVAR
LYEMAKHGQLKIPAINVNNAVTKSKFDNLYGCRESLLDGLKRATDVMIAGKVALILGYGDVGKGCAQALRGQGATVLVAE
IDPICALQAAMEGYRVVTLDDVAEQVDIVVTATGNYHVVTHDHMKRMRNQAILCNIGHFDSEIDIQSLKQYQWENIKPQV
DHVIFPDGKRIIILAEGRLVNLGCATGHPSFVMSASFTNQVLAQIELFQNSSQYQNQVYVLPKVLDEKVARLHLGRIGAK
LTQLSNEQADYIGVDKNGPYKPDHYRY
;
_struct_ref.pdbx_align_begin           15 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8WZ8 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 11 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 437 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A2S6F4T2 
_struct_ref_seq.db_align_beg                  15 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  441 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       15 
_struct_ref_seq.pdbx_auth_seq_align_end       441 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8WZ8 MET A 1  ? UNP A0A2S6F4T2 ?   ?  'initiating methionine' 5  1  
1 8WZ8 GLY A 2  ? UNP A0A2S6F4T2 ?   ?  'expression tag'        6  2  
1 8WZ8 HIS A 3  ? UNP A0A2S6F4T2 ?   ?  'expression tag'        7  3  
1 8WZ8 HIS A 4  ? UNP A0A2S6F4T2 ?   ?  'expression tag'        8  4  
1 8WZ8 HIS A 5  ? UNP A0A2S6F4T2 ?   ?  'expression tag'        9  5  
1 8WZ8 HIS A 6  ? UNP A0A2S6F4T2 ?   ?  'expression tag'        10 6  
1 8WZ8 HIS A 7  ? UNP A0A2S6F4T2 ?   ?  'expression tag'        11 7  
1 8WZ8 HIS A 8  ? UNP A0A2S6F4T2 ?   ?  'expression tag'        12 8  
1 8WZ8 HIS A 9  ? UNP A0A2S6F4T2 ?   ?  'expression tag'        13 9  
1 8WZ8 HIS A 10 ? UNP A0A2S6F4T2 ?   ?  'expression tag'        14 10 
1 8WZ8 ALA A 63 ? UNP A0A2S6F4T2 THR 67 'engineered mutation'   67 11 
1 8WZ8 ALA A 65 ? UNP A0A2S6F4T2 GLN 69 'engineered mutation'   69 12 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 9320  ? 
1 MORE         -87   ? 
1 'SSA (A^2)'  30020 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1,2 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z     1.0000000000  0.0000000000 0.0000000000 0.0000000000  0.0000000000 1.0000000000  
0.0000000000 0.0000000000    0.0000000000 0.0000000000 1.0000000000 0.0000000000 
2 'crystal symmetry operation' 4_545 -x,-y-1,z -1.0000000000 0.0000000000 0.0000000000 65.8000000000 0.0000000000 -1.0000000000 
0.0000000000 -113.9689431380 0.0000000000 0.0000000000 1.0000000000 0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLU A 17  ? SER A 19  ? GLU A 21  SER A 23  5 ? 3  
HELX_P HELX_P2  AA2 LEU A 20  ? THR A 33  ? LEU A 24  THR A 37  1 ? 14 
HELX_P HELX_P3  AA3 MET A 35  ? SER A 46  ? MET A 39  SER A 50  1 ? 12 
HELX_P HELX_P4  AA4 ALA A 63  ? LEU A 76  ? ALA A 67  LEU A 80  1 ? 14 
HELX_P HELX_P5  AA5 GLN A 91  ? LYS A 101 ? GLN A 95  LYS A 105 1 ? 11 
HELX_P HELX_P6  AA6 THR A 112 ? THR A 123 ? THR A 116 THR A 127 1 ? 12 
HELX_P HELX_P7  AA7 GLY A 140 ? HIS A 150 ? GLY A 144 HIS A 154 1 ? 11 
HELX_P HELX_P8  AA8 LEU A 153 ? ILE A 157 ? LEU A 157 ILE A 161 5 ? 5  
HELX_P HELX_P9  AA9 THR A 164 ? HIS A 177 ? THR A 168 HIS A 181 1 ? 14 
HELX_P HELX_P10 AB1 ALA A 190 ? LYS A 195 ? ALA A 194 LYS A 199 1 ? 6  
HELX_P HELX_P11 AB2 PHE A 196 ? ASP A 215 ? PHE A 200 ASP A 219 1 ? 20 
HELX_P HELX_P12 AB3 GLY A 229 ? GLN A 242 ? GLY A 233 GLN A 246 1 ? 14 
HELX_P HELX_P13 AB4 ASP A 252 ? GLU A 262 ? ASP A 256 GLU A 266 1 ? 11 
HELX_P HELX_P14 AB5 THR A 268 ? ALA A 273 ? THR A 272 ALA A 277 1 ? 6  
HELX_P HELX_P15 AB6 THR A 290 ? MET A 297 ? THR A 294 MET A 301 1 ? 8  
HELX_P HELX_P16 AB7 PHE A 309 ? ILE A 313 ? PHE A 313 ILE A 317 5 ? 5  
HELX_P HELX_P17 AB8 ASP A 314 ? LYS A 319 ? ASP A 318 LYS A 323 5 ? 6  
HELX_P HELX_P18 AB9 GLU A 346 ? ARG A 348 ? GLU A 350 ARG A 352 5 ? 3  
HELX_P HELX_P19 AC1 LEU A 349 ? ALA A 355 ? LEU A 353 ALA A 359 1 ? 7  
HELX_P HELX_P20 AC2 PRO A 359 ? SER A 381 ? PRO A 363 SER A 385 1 ? 23 
HELX_P HELX_P21 AC3 SER A 382 ? TYR A 384 ? SER A 386 TYR A 388 5 ? 3  
HELX_P HELX_P22 AC4 PRO A 392 ? GLY A 405 ? PRO A 396 GLY A 409 1 ? 14 
HELX_P HELX_P23 AC5 SER A 415 ? GLY A 423 ? SER A 419 GLY A 427 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLY 
_struct_mon_prot_cis.label_seq_id           428 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLY 
_struct_mon_prot_cis.auth_seq_id            432 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    429 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     433 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       0.22 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 8 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA2 1 2 ? parallel      
AA2 2 3 ? parallel      
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA2 5 6 ? parallel      
AA2 6 7 ? anti-parallel 
AA2 7 8 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 105 ? PHE A 106 ? VAL A 109 PHE A 110 
AA1 2 GLU A 79  ? SER A 83  ? GLU A 83  SER A 87  
AA1 3 ARG A 55  ? CYS A 59  ? ARG A 59  CYS A 63  
AA1 4 LEU A 134 ? ASP A 137 ? LEU A 138 ASP A 141 
AA1 5 GLY A 159 ? GLU A 162 ? GLY A 163 GLU A 166 
AA1 6 ALA A 184 ? ASN A 186 ? ALA A 188 ASN A 190 
AA1 7 VAL A 388 ? TYR A 389 ? VAL A 392 TYR A 393 
AA2 1 ARG A 265 ? VAL A 266 ? ARG A 269 VAL A 270 
AA2 2 THR A 245 ? ALA A 249 ? THR A 249 ALA A 253 
AA2 3 VAL A 222 ? LEU A 226 ? VAL A 226 LEU A 230 
AA2 4 ILE A 278 ? THR A 281 ? ILE A 282 THR A 285 
AA2 5 ALA A 301 ? ASN A 305 ? ALA A 305 ASN A 309 
AA2 6 ARG A 340 ? LEU A 344 ? ARG A 344 LEU A 348 
AA2 7 VAL A 330 ? ILE A 334 ? VAL A 334 ILE A 338 
AA2 8 GLN A 322 ? LYS A 327 ? GLN A 326 LYS A 331 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O PHE A 106 ? O PHE A 110 N TRP A 82  ? N TRP A 86  
AA1 2 3 O ARG A 81  ? O ARG A 85  N GLY A 58  ? N GLY A 62  
AA1 3 4 N ALA A 57  ? N ALA A 61  O LEU A 136 ? O LEU A 140 
AA1 4 5 N LEU A 135 ? N LEU A 139 O GLY A 159 ? O GLY A 163 
AA1 5 6 N VAL A 160 ? N VAL A 164 O ILE A 185 ? O ILE A 189 
AA1 6 7 N ASN A 186 ? N ASN A 190 O TYR A 389 ? O TYR A 393 
AA2 1 2 O ARG A 265 ? O ARG A 269 N VAL A 248 ? N VAL A 252 
AA2 2 3 O LEU A 247 ? O LEU A 251 N ALA A 223 ? N ALA A 227 
AA2 3 4 N LEU A 224 ? N LEU A 228 O VAL A 280 ? O VAL A 284 
AA2 4 5 N VAL A 279 ? N VAL A 283 O CYS A 304 ? O CYS A 308 
AA2 5 6 N LEU A 303 ? N LEU A 307 O ILE A 342 ? O ILE A 346 
AA2 6 7 O ILE A 343 ? O ILE A 347 N ASP A 331 ? N ASP A 335 
AA2 7 8 O VAL A 330 ? O VAL A 334 N ILE A 326 ? N ILE A 330 
# 
_pdbx_entry_details.entry_id                   8WZ8 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 16  ? ? -83.07  30.91   
2  1 LYS A 53  ? ? 52.40   71.99   
3  1 HIS A 65  ? ? -28.37  114.97  
4  1 LYS A 197 ? ? -102.79 -68.55  
5  1 PHE A 200 ? ? -137.70 -64.35  
6  1 LEU A 203 ? ? -90.04  -65.91  
7  1 ALA A 286 ? ? -140.92 31.94   
8  1 SER A 315 ? ? -30.41  -26.36  
9  1 LEU A 353 ? ? -39.03  108.47  
10 1 ALA A 359 ? ? -139.97 -139.22 
11 1 ASN A 390 ? ? -90.92  55.83   
# 
loop_
_pdbx_struct_special_symmetry.id 
_pdbx_struct_special_symmetry.PDB_model_num 
_pdbx_struct_special_symmetry.auth_asym_id 
_pdbx_struct_special_symmetry.auth_comp_id 
_pdbx_struct_special_symmetry.auth_seq_id 
_pdbx_struct_special_symmetry.PDB_ins_code 
_pdbx_struct_special_symmetry.label_asym_id 
_pdbx_struct_special_symmetry.label_comp_id 
_pdbx_struct_special_symmetry.label_seq_id 
1 1 A HOH 646 ? D HOH . 
2 1 A HOH 717 ? D HOH . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 5  ? A MET 1  
2  1 Y 1 A GLY 6  ? A GLY 2  
3  1 Y 1 A HIS 7  ? A HIS 3  
4  1 Y 1 A HIS 8  ? A HIS 4  
5  1 Y 1 A HIS 9  ? A HIS 5  
6  1 Y 1 A HIS 10 ? A HIS 6  
7  1 Y 1 A HIS 11 ? A HIS 7  
8  1 Y 1 A HIS 12 ? A HIS 8  
9  1 Y 1 A HIS 13 ? A HIS 9  
10 1 Y 1 A HIS 14 ? A HIS 10 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
NAD PA   P N S 250 
NAD O1A  O N N 251 
NAD O2A  O N N 252 
NAD O5B  O N N 253 
NAD C5B  C N N 254 
NAD C4B  C N R 255 
NAD O4B  O N N 256 
NAD C3B  C N S 257 
NAD O3B  O N N 258 
NAD C2B  C N R 259 
NAD O2B  O N N 260 
NAD C1B  C N R 261 
NAD N9A  N Y N 262 
NAD C8A  C Y N 263 
NAD N7A  N Y N 264 
NAD C5A  C Y N 265 
NAD C6A  C Y N 266 
NAD N6A  N N N 267 
NAD N1A  N Y N 268 
NAD C2A  C Y N 269 
NAD N3A  N Y N 270 
NAD C4A  C Y N 271 
NAD O3   O N N 272 
NAD PN   P N N 273 
NAD O1N  O N N 274 
NAD O2N  O N N 275 
NAD O5D  O N N 276 
NAD C5D  C N N 277 
NAD C4D  C N R 278 
NAD O4D  O N N 279 
NAD C3D  C N S 280 
NAD O3D  O N N 281 
NAD C2D  C N R 282 
NAD O2D  O N N 283 
NAD C1D  C N R 284 
NAD N1N  N Y N 285 
NAD C2N  C Y N 286 
NAD C3N  C Y N 287 
NAD C7N  C N N 288 
NAD O7N  O N N 289 
NAD N7N  N N N 290 
NAD C4N  C Y N 291 
NAD C5N  C Y N 292 
NAD C6N  C Y N 293 
NAD HOA2 H N N 294 
NAD H51A H N N 295 
NAD H52A H N N 296 
NAD H4B  H N N 297 
NAD H3B  H N N 298 
NAD HO3A H N N 299 
NAD H2B  H N N 300 
NAD HO2A H N N 301 
NAD H1B  H N N 302 
NAD H8A  H N N 303 
NAD H61A H N N 304 
NAD H62A H N N 305 
NAD H2A  H N N 306 
NAD H51N H N N 307 
NAD H52N H N N 308 
NAD H4D  H N N 309 
NAD H3D  H N N 310 
NAD HO3N H N N 311 
NAD H2D  H N N 312 
NAD HO2N H N N 313 
NAD H1D  H N N 314 
NAD H2N  H N N 315 
NAD H71N H N N 316 
NAD H72N H N N 317 
NAD H4N  H N N 318 
NAD H5N  H N N 319 
NAD H6N  H N N 320 
PHE N    N N N 321 
PHE CA   C N S 322 
PHE C    C N N 323 
PHE O    O N N 324 
PHE CB   C N N 325 
PHE CG   C Y N 326 
PHE CD1  C Y N 327 
PHE CD2  C Y N 328 
PHE CE1  C Y N 329 
PHE CE2  C Y N 330 
PHE CZ   C Y N 331 
PHE OXT  O N N 332 
PHE H    H N N 333 
PHE H2   H N N 334 
PHE HA   H N N 335 
PHE HB2  H N N 336 
PHE HB3  H N N 337 
PHE HD1  H N N 338 
PHE HD2  H N N 339 
PHE HE1  H N N 340 
PHE HE2  H N N 341 
PHE HZ   H N N 342 
PHE HXT  H N N 343 
PRO N    N N N 344 
PRO CA   C N S 345 
PRO C    C N N 346 
PRO O    O N N 347 
PRO CB   C N N 348 
PRO CG   C N N 349 
PRO CD   C N N 350 
PRO OXT  O N N 351 
PRO H    H N N 352 
PRO HA   H N N 353 
PRO HB2  H N N 354 
PRO HB3  H N N 355 
PRO HG2  H N N 356 
PRO HG3  H N N 357 
PRO HD2  H N N 358 
PRO HD3  H N N 359 
PRO HXT  H N N 360 
SER N    N N N 361 
SER CA   C N S 362 
SER C    C N N 363 
SER O    O N N 364 
SER CB   C N N 365 
SER OG   O N N 366 
SER OXT  O N N 367 
SER H    H N N 368 
SER H2   H N N 369 
SER HA   H N N 370 
SER HB2  H N N 371 
SER HB3  H N N 372 
SER HG   H N N 373 
SER HXT  H N N 374 
SO4 S    S N N 375 
SO4 O1   O N N 376 
SO4 O2   O N N 377 
SO4 O3   O N N 378 
SO4 O4   O N N 379 
THR N    N N N 380 
THR CA   C N S 381 
THR C    C N N 382 
THR O    O N N 383 
THR CB   C N R 384 
THR OG1  O N N 385 
THR CG2  C N N 386 
THR OXT  O N N 387 
THR H    H N N 388 
THR H2   H N N 389 
THR HA   H N N 390 
THR HB   H N N 391 
THR HG1  H N N 392 
THR HG21 H N N 393 
THR HG22 H N N 394 
THR HG23 H N N 395 
THR HXT  H N N 396 
TRP N    N N N 397 
TRP CA   C N S 398 
TRP C    C N N 399 
TRP O    O N N 400 
TRP CB   C N N 401 
TRP CG   C Y N 402 
TRP CD1  C Y N 403 
TRP CD2  C Y N 404 
TRP NE1  N Y N 405 
TRP CE2  C Y N 406 
TRP CE3  C Y N 407 
TRP CZ2  C Y N 408 
TRP CZ3  C Y N 409 
TRP CH2  C Y N 410 
TRP OXT  O N N 411 
TRP H    H N N 412 
TRP H2   H N N 413 
TRP HA   H N N 414 
TRP HB2  H N N 415 
TRP HB3  H N N 416 
TRP HD1  H N N 417 
TRP HE1  H N N 418 
TRP HE3  H N N 419 
TRP HZ2  H N N 420 
TRP HZ3  H N N 421 
TRP HH2  H N N 422 
TRP HXT  H N N 423 
TYR N    N N N 424 
TYR CA   C N S 425 
TYR C    C N N 426 
TYR O    O N N 427 
TYR CB   C N N 428 
TYR CG   C Y N 429 
TYR CD1  C Y N 430 
TYR CD2  C Y N 431 
TYR CE1  C Y N 432 
TYR CE2  C Y N 433 
TYR CZ   C Y N 434 
TYR OH   O N N 435 
TYR OXT  O N N 436 
TYR H    H N N 437 
TYR H2   H N N 438 
TYR HA   H N N 439 
TYR HB2  H N N 440 
TYR HB3  H N N 441 
TYR HD1  H N N 442 
TYR HD2  H N N 443 
TYR HE1  H N N 444 
TYR HE2  H N N 445 
TYR HH   H N N 446 
TYR HXT  H N N 447 
VAL N    N N N 448 
VAL CA   C N S 449 
VAL C    C N N 450 
VAL O    O N N 451 
VAL CB   C N N 452 
VAL CG1  C N N 453 
VAL CG2  C N N 454 
VAL OXT  O N N 455 
VAL H    H N N 456 
VAL H2   H N N 457 
VAL HA   H N N 458 
VAL HB   H N N 459 
VAL HG11 H N N 460 
VAL HG12 H N N 461 
VAL HG13 H N N 462 
VAL HG21 H N N 463 
VAL HG22 H N N 464 
VAL HG23 H N N 465 
VAL HXT  H N N 466 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
NAD PA  O1A  doub N N 237 
NAD PA  O2A  sing N N 238 
NAD PA  O5B  sing N N 239 
NAD PA  O3   sing N N 240 
NAD O2A HOA2 sing N N 241 
NAD O5B C5B  sing N N 242 
NAD C5B C4B  sing N N 243 
NAD C5B H51A sing N N 244 
NAD C5B H52A sing N N 245 
NAD C4B O4B  sing N N 246 
NAD C4B C3B  sing N N 247 
NAD C4B H4B  sing N N 248 
NAD O4B C1B  sing N N 249 
NAD C3B O3B  sing N N 250 
NAD C3B C2B  sing N N 251 
NAD C3B H3B  sing N N 252 
NAD O3B HO3A sing N N 253 
NAD C2B O2B  sing N N 254 
NAD C2B C1B  sing N N 255 
NAD C2B H2B  sing N N 256 
NAD O2B HO2A sing N N 257 
NAD C1B N9A  sing N N 258 
NAD C1B H1B  sing N N 259 
NAD N9A C8A  sing Y N 260 
NAD N9A C4A  sing Y N 261 
NAD C8A N7A  doub Y N 262 
NAD C8A H8A  sing N N 263 
NAD N7A C5A  sing Y N 264 
NAD C5A C6A  sing Y N 265 
NAD C5A C4A  doub Y N 266 
NAD C6A N6A  sing N N 267 
NAD C6A N1A  doub Y N 268 
NAD N6A H61A sing N N 269 
NAD N6A H62A sing N N 270 
NAD N1A C2A  sing Y N 271 
NAD C2A N3A  doub Y N 272 
NAD C2A H2A  sing N N 273 
NAD N3A C4A  sing Y N 274 
NAD O3  PN   sing N N 275 
NAD PN  O1N  doub N N 276 
NAD PN  O2N  sing N N 277 
NAD PN  O5D  sing N N 278 
NAD O5D C5D  sing N N 279 
NAD C5D C4D  sing N N 280 
NAD C5D H51N sing N N 281 
NAD C5D H52N sing N N 282 
NAD C4D O4D  sing N N 283 
NAD C4D C3D  sing N N 284 
NAD C4D H4D  sing N N 285 
NAD O4D C1D  sing N N 286 
NAD C3D O3D  sing N N 287 
NAD C3D C2D  sing N N 288 
NAD C3D H3D  sing N N 289 
NAD O3D HO3N sing N N 290 
NAD C2D O2D  sing N N 291 
NAD C2D C1D  sing N N 292 
NAD C2D H2D  sing N N 293 
NAD O2D HO2N sing N N 294 
NAD C1D N1N  sing N N 295 
NAD C1D H1D  sing N N 296 
NAD N1N C2N  sing Y N 297 
NAD N1N C6N  doub Y N 298 
NAD C2N C3N  doub Y N 299 
NAD C2N H2N  sing N N 300 
NAD C3N C7N  sing N N 301 
NAD C3N C4N  sing Y N 302 
NAD C7N O7N  doub N N 303 
NAD C7N N7N  sing N N 304 
NAD N7N H71N sing N N 305 
NAD N7N H72N sing N N 306 
NAD C4N C5N  doub Y N 307 
NAD C4N H4N  sing N N 308 
NAD C5N C6N  sing Y N 309 
NAD C5N H5N  sing N N 310 
NAD C6N H6N  sing N N 311 
PHE N   CA   sing N N 312 
PHE N   H    sing N N 313 
PHE N   H2   sing N N 314 
PHE CA  C    sing N N 315 
PHE CA  CB   sing N N 316 
PHE CA  HA   sing N N 317 
PHE C   O    doub N N 318 
PHE C   OXT  sing N N 319 
PHE CB  CG   sing N N 320 
PHE CB  HB2  sing N N 321 
PHE CB  HB3  sing N N 322 
PHE CG  CD1  doub Y N 323 
PHE CG  CD2  sing Y N 324 
PHE CD1 CE1  sing Y N 325 
PHE CD1 HD1  sing N N 326 
PHE CD2 CE2  doub Y N 327 
PHE CD2 HD2  sing N N 328 
PHE CE1 CZ   doub Y N 329 
PHE CE1 HE1  sing N N 330 
PHE CE2 CZ   sing Y N 331 
PHE CE2 HE2  sing N N 332 
PHE CZ  HZ   sing N N 333 
PHE OXT HXT  sing N N 334 
PRO N   CA   sing N N 335 
PRO N   CD   sing N N 336 
PRO N   H    sing N N 337 
PRO CA  C    sing N N 338 
PRO CA  CB   sing N N 339 
PRO CA  HA   sing N N 340 
PRO C   O    doub N N 341 
PRO C   OXT  sing N N 342 
PRO CB  CG   sing N N 343 
PRO CB  HB2  sing N N 344 
PRO CB  HB3  sing N N 345 
PRO CG  CD   sing N N 346 
PRO CG  HG2  sing N N 347 
PRO CG  HG3  sing N N 348 
PRO CD  HD2  sing N N 349 
PRO CD  HD3  sing N N 350 
PRO OXT HXT  sing N N 351 
SER N   CA   sing N N 352 
SER N   H    sing N N 353 
SER N   H2   sing N N 354 
SER CA  C    sing N N 355 
SER CA  CB   sing N N 356 
SER CA  HA   sing N N 357 
SER C   O    doub N N 358 
SER C   OXT  sing N N 359 
SER CB  OG   sing N N 360 
SER CB  HB2  sing N N 361 
SER CB  HB3  sing N N 362 
SER OG  HG   sing N N 363 
SER OXT HXT  sing N N 364 
SO4 S   O1   doub N N 365 
SO4 S   O2   doub N N 366 
SO4 S   O3   sing N N 367 
SO4 S   O4   sing N N 368 
THR N   CA   sing N N 369 
THR N   H    sing N N 370 
THR N   H2   sing N N 371 
THR CA  C    sing N N 372 
THR CA  CB   sing N N 373 
THR CA  HA   sing N N 374 
THR C   O    doub N N 375 
THR C   OXT  sing N N 376 
THR CB  OG1  sing N N 377 
THR CB  CG2  sing N N 378 
THR CB  HB   sing N N 379 
THR OG1 HG1  sing N N 380 
THR CG2 HG21 sing N N 381 
THR CG2 HG22 sing N N 382 
THR CG2 HG23 sing N N 383 
THR OXT HXT  sing N N 384 
TRP N   CA   sing N N 385 
TRP N   H    sing N N 386 
TRP N   H2   sing N N 387 
TRP CA  C    sing N N 388 
TRP CA  CB   sing N N 389 
TRP CA  HA   sing N N 390 
TRP C   O    doub N N 391 
TRP C   OXT  sing N N 392 
TRP CB  CG   sing N N 393 
TRP CB  HB2  sing N N 394 
TRP CB  HB3  sing N N 395 
TRP CG  CD1  doub Y N 396 
TRP CG  CD2  sing Y N 397 
TRP CD1 NE1  sing Y N 398 
TRP CD1 HD1  sing N N 399 
TRP CD2 CE2  doub Y N 400 
TRP CD2 CE3  sing Y N 401 
TRP NE1 CE2  sing Y N 402 
TRP NE1 HE1  sing N N 403 
TRP CE2 CZ2  sing Y N 404 
TRP CE3 CZ3  doub Y N 405 
TRP CE3 HE3  sing N N 406 
TRP CZ2 CH2  doub Y N 407 
TRP CZ2 HZ2  sing N N 408 
TRP CZ3 CH2  sing Y N 409 
TRP CZ3 HZ3  sing N N 410 
TRP CH2 HH2  sing N N 411 
TRP OXT HXT  sing N N 412 
TYR N   CA   sing N N 413 
TYR N   H    sing N N 414 
TYR N   H2   sing N N 415 
TYR CA  C    sing N N 416 
TYR CA  CB   sing N N 417 
TYR CA  HA   sing N N 418 
TYR C   O    doub N N 419 
TYR C   OXT  sing N N 420 
TYR CB  CG   sing N N 421 
TYR CB  HB2  sing N N 422 
TYR CB  HB3  sing N N 423 
TYR CG  CD1  doub Y N 424 
TYR CG  CD2  sing Y N 425 
TYR CD1 CE1  sing Y N 426 
TYR CD1 HD1  sing N N 427 
TYR CD2 CE2  doub Y N 428 
TYR CD2 HD2  sing N N 429 
TYR CE1 CZ   doub Y N 430 
TYR CE1 HE1  sing N N 431 
TYR CE2 CZ   sing Y N 432 
TYR CE2 HE2  sing N N 433 
TYR CZ  OH   sing N N 434 
TYR OH  HH   sing N N 435 
TYR OXT HXT  sing N N 436 
VAL N   CA   sing N N 437 
VAL N   H    sing N N 438 
VAL N   H2   sing N N 439 
VAL CA  C    sing N N 440 
VAL CA  CB   sing N N 441 
VAL CA  HA   sing N N 442 
VAL C   O    doub N N 443 
VAL C   OXT  sing N N 444 
VAL CB  CG1  sing N N 445 
VAL CB  CG2  sing N N 446 
VAL CB  HB   sing N N 447 
VAL CG1 HG11 sing N N 448 
VAL CG1 HG12 sing N N 449 
VAL CG1 HG13 sing N N 450 
VAL CG2 HG21 sing N N 451 
VAL CG2 HG22 sing N N 452 
VAL CG2 HG23 sing N N 453 
VAL OXT HXT  sing N N 454 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Natural Science Foundation of China (NSFC)' China 32370196 1 
'National Natural Science Foundation of China (NSFC)' China 32071215 2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             other 
_pdbx_initial_refinement_model.source_name      Other 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          Q5ZTY7 
# 
_atom_sites.entry_id                    8WZ8 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.007599 
_atom_sites.fract_transf_matrix[1][2]   0.004387 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.008774 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008629 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
H 1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N 7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
P 15 15 6.4348  1.9067  4.1793 27.1570 1.7801 0.5260  1.4909 68.1645 1.2732   
S 16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0555   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N   . GLN A 1 11  ? 17.064 -12.432 -4.469  1.000 100.978 0 15  GLN A N   1 ? 
ATOM   2    C CA  . GLN A 1 11  ? 17.245 -13.594 -3.601  1.000 100.338 0 15  GLN A CA  1 ? 
ATOM   3    C C   . GLN A 1 11  ? 16.888 -14.905 -4.287  1.000 96.785  0 15  GLN A C   1 ? 
ATOM   4    O O   . GLN A 1 11  ? 15.744 -15.364 -4.202  1.000 92.353  0 15  GLN A O   1 ? 
ATOM   5    C CB  . GLN A 1 11  ? 16.397 -13.460 -2.349  1.000 103.023 0 15  GLN A CB  1 ? 
ATOM   6    C CG  . GLN A 1 11  ? 16.749 -12.298 -1.478  1.000 107.781 0 15  GLN A CG  1 ? 
ATOM   7    C CD  . GLN A 1 11  ? 16.190 -12.467 -0.084  1.000 111.050 0 15  GLN A CD  1 ? 
ATOM   8    O OE1 . GLN A 1 11  ? 15.272 -13.260 0.134   1.000 112.445 0 15  GLN A OE1 1 ? 
ATOM   9    N NE2 . GLN A 1 11  ? 16.736 -11.721 0.869   1.000 113.148 0 15  GLN A NE2 1 ? 
ATOM   10   N N   . ASP A 1 12  ? 17.868 -15.527 -4.943  1.000 94.232  0 16  ASP A N   1 ? 
ATOM   11   C CA  . ASP A 1 12  ? 17.619 -16.741 -5.708  1.000 89.271  0 16  ASP A CA  1 ? 
ATOM   12   C C   . ASP A 1 12  ? 17.627 -17.987 -4.831  1.000 80.736  0 16  ASP A C   1 ? 
ATOM   13   O O   . ASP A 1 12  ? 17.967 -19.083 -5.304  1.000 78.457  0 16  ASP A O   1 ? 
ATOM   14   C CB  . ASP A 1 12  ? 18.633 -16.860 -6.848  1.000 84.028  0 16  ASP A CB  1 ? 
ATOM   15   C CG  . ASP A 1 12  ? 18.175 -17.809 -7.937  1.000 75.693  0 16  ASP A CG  1 ? 
ATOM   16   O OD1 . ASP A 1 12  ? 17.016 -18.277 -7.874  1.000 72.193  0 16  ASP A OD1 1 ? 
ATOM   17   O OD2 . ASP A 1 12  ? 18.975 -18.087 -8.847  1.000 73.485  0 16  ASP A OD2 1 ? 
ATOM   18   N N   . TYR A 1 13  ? 17.225 -17.857 -3.571  1.000 74.954  0 17  TYR A N   1 ? 
ATOM   19   C CA  . TYR A 1 13  ? 17.258 -18.952 -2.616  1.000 69.000  0 17  TYR A CA  1 ? 
ATOM   20   C C   . TYR A 1 13  ? 15.903 -19.080 -1.935  1.000 68.319  0 17  TYR A C   1 ? 
ATOM   21   O O   . TYR A 1 13  ? 15.038 -18.207 -2.046  1.000 69.295  0 17  TYR A O   1 ? 
ATOM   22   C CB  . TYR A 1 13  ? 18.379 -18.732 -1.597  1.000 64.671  0 17  TYR A CB  1 ? 
ATOM   23   C CG  . TYR A 1 13  ? 18.147 -17.614 -0.605  1.000 65.047  0 17  TYR A CG  1 ? 
ATOM   24   C CD1 . TYR A 1 13  ? 17.338 -17.811 0.517   1.000 76.851  0 17  TYR A CD1 1 ? 
ATOM   25   C CD2 . TYR A 1 13  ? 18.775 -16.381 -0.755  1.000 59.739  0 17  TYR A CD2 1 ? 
ATOM   26   C CE1 . TYR A 1 13  ? 17.134 -16.809 1.442   1.000 84.402  0 17  TYR A CE1 1 ? 
ATOM   27   C CE2 . TYR A 1 13  ? 18.580 -15.365 0.173   1.000 70.401  0 17  TYR A CE2 1 ? 
ATOM   28   C CZ  . TYR A 1 13  ? 17.753 -15.586 1.269   1.000 85.981  0 17  TYR A CZ  1 ? 
ATOM   29   O OH  . TYR A 1 13  ? 17.540 -14.592 2.200   1.000 97.643  0 17  TYR A OH  1 ? 
ATOM   30   N N   . LYS A 1 14  ? 15.720 -20.188 -1.222  1.000 71.198  0 18  LYS A N   1 ? 
ATOM   31   C CA  . LYS A 1 14  ? 14.523 -20.375 -0.401  1.000 77.193  0 18  LYS A CA  1 ? 
ATOM   32   C C   . LYS A 1 14  ? 14.905 -21.302 0.753   1.000 79.681  0 18  LYS A C   1 ? 
ATOM   33   O O   . LYS A 1 14  ? 14.839 -22.529 0.637   1.000 80.957  0 18  LYS A O   1 ? 
ATOM   34   C CB  . LYS A 1 14  ? 13.355 -20.926 -1.206  1.000 80.460  0 18  LYS A CB  1 ? 
ATOM   35   C CG  . LYS A 1 14  ? 12.175 -21.407 -0.364  1.000 80.218  0 18  LYS A CG  1 ? 
ATOM   36   C CD  . LYS A 1 14  ? 11.225 -20.298 0.040   1.000 83.818  0 18  LYS A CD  1 ? 
ATOM   37   C CE  . LYS A 1 14  ? 9.784  -20.777 -0.034  1.000 87.784  0 18  LYS A CE  1 ? 
ATOM   38   N NZ  . LYS A 1 14  ? 8.858  -19.932 0.766   1.000 91.735  0 18  LYS A NZ  1 ? 
ATOM   39   N N   . VAL A 1 15  ? 15.313 -20.696 1.860   1.000 83.397  0 19  VAL A N   1 ? 
ATOM   40   C CA  . VAL A 1 15  ? 15.604 -21.422 3.082   1.000 81.710  0 19  VAL A CA  1 ? 
ATOM   41   C C   . VAL A 1 15  ? 14.567 -21.034 4.128   1.000 81.552  0 19  VAL A C   1 ? 
ATOM   42   O O   . VAL A 1 15  ? 13.793 -20.091 3.959   1.000 84.984  0 19  VAL A O   1 ? 
ATOM   43   C CB  . VAL A 1 15  ? 17.034 -21.163 3.592   1.000 84.192  0 19  VAL A CB  1 ? 
ATOM   44   C CG1 . VAL A 1 15  ? 18.032 -21.264 2.454   1.000 84.894  0 19  VAL A CG1 1 ? 
ATOM   45   C CG2 . VAL A 1 15  ? 17.117 -19.799 4.274   1.000 87.350  0 19  VAL A CG2 1 ? 
ATOM   46   N N   . ALA A 1 16  ? 14.558 -21.785 5.226   1.000 77.436  0 20  ALA A N   1 ? 
ATOM   47   C CA  . ALA A 1 16  ? 13.598 -21.522 6.288   1.000 69.553  0 20  ALA A CA  1 ? 
ATOM   48   C C   . ALA A 1 16  ? 13.965 -20.261 7.062   1.000 72.453  0 20  ALA A C   1 ? 
ATOM   49   O O   . ALA A 1 16  ? 13.085 -19.470 7.433   1.000 68.119  0 20  ALA A O   1 ? 
ATOM   50   C CB  . ALA A 1 16  ? 13.520 -22.735 7.217   1.000 55.844  0 20  ALA A CB  1 ? 
ATOM   51   N N   . GLU A 1 17  ? 15.264 -20.048 7.293   1.000 73.440  0 21  GLU A N   1 ? 
ATOM   52   C CA  . GLU A 1 17  ? 15.714 -19.008 8.215   1.000 77.699  0 21  GLU A CA  1 ? 
ATOM   53   C C   . GLU A 1 17  ? 17.140 -18.618 7.831   1.000 80.810  0 21  GLU A C   1 ? 
ATOM   54   O O   . GLU A 1 17  ? 18.089 -19.332 8.172   1.000 88.221  0 21  GLU A O   1 ? 
ATOM   55   C CB  . GLU A 1 17  ? 15.643 -19.497 9.648   1.000 76.920  0 21  GLU A CB  1 ? 
ATOM   56   C CG  . GLU A 1 17  ? 16.164 -18.511 10.647  1.000 87.350  0 21  GLU A CG  1 ? 
ATOM   57   C CD  . GLU A 1 17  ? 15.227 -18.352 11.809  1.000 96.825  0 21  GLU A CD  1 ? 
ATOM   58   O OE1 . GLU A 1 17  ? 15.568 -18.835 12.910  1.000 94.564  0 21  GLU A OE1 1 ? 
ATOM   59   O OE2 . GLU A 1 17  ? 14.146 -17.751 11.616  1.000 103.907 0 21  GLU A OE2 1 ? 
ATOM   60   N N   . ILE A 1 18  ? 17.281 -17.481 7.140   1.000 72.530  0 22  ILE A N   1 ? 
ATOM   61   C CA  . ILE A 1 18  ? 18.602 -17.024 6.715   1.000 67.621  0 22  ILE A CA  1 ? 
ATOM   62   C C   . ILE A 1 18  ? 19.493 -16.614 7.878   1.000 71.627  0 22  ILE A C   1 ? 
ATOM   63   O O   . ILE A 1 18  ? 20.709 -16.481 7.699   1.000 72.090  0 22  ILE A O   1 ? 
ATOM   64   C CB  . ILE A 1 18  ? 18.485 -15.853 5.718   1.000 63.465  0 22  ILE A CB  1 ? 
ATOM   65   C CG1 . ILE A 1 18  ? 19.739 -15.765 4.840   1.000 57.662  0 22  ILE A CG1 1 ? 
ATOM   66   C CG2 . ILE A 1 18  ? 18.254 -14.550 6.452   1.000 61.957  0 22  ILE A CG2 1 ? 
ATOM   67   C CD1 . ILE A 1 18  ? 20.087 -17.049 4.146   1.000 52.972  0 22  ILE A CD1 1 ? 
ATOM   68   N N   . SER A 1 19  ? 18.931 -16.433 9.074   1.000 71.448  0 23  SER A N   1 ? 
ATOM   69   C CA  . SER A 1 19  ? 19.734 -15.963 10.194  1.000 65.139  0 23  SER A CA  1 ? 
ATOM   70   C C   . SER A 1 19  ? 20.692 -17.018 10.722  1.000 61.057  0 23  SER A C   1 ? 
ATOM   71   O O   . SER A 1 19  ? 21.669 -16.663 11.388  1.000 55.728  0 23  SER A O   1 ? 
ATOM   72   C CB  . SER A 1 19  ? 18.837 -15.488 11.327  1.000 69.674  0 23  SER A CB  1 ? 
ATOM   73   O OG  . SER A 1 19  ? 19.519 -14.486 12.059  1.000 78.407  0 23  SER A OG  1 ? 
ATOM   74   N N   . LEU A 1 20  ? 20.443 -18.296 10.439  1.000 64.676  0 24  LEU A N   1 ? 
ATOM   75   C CA  . LEU A 1 20  ? 21.269 -19.397 10.918  1.000 58.510  0 24  LEU A CA  1 ? 
ATOM   76   C C   . LEU A 1 20  ? 22.578 -19.535 10.158  1.000 60.931  0 24  LEU A C   1 ? 
ATOM   77   O O   . LEU A 1 20  ? 23.289 -20.526 10.360  1.000 67.761  0 24  LEU A O   1 ? 
ATOM   78   C CB  . LEU A 1 20  ? 20.491 -20.707 10.819  1.000 54.064  0 24  LEU A CB  1 ? 
ATOM   79   C CG  . LEU A 1 20  ? 19.121 -20.680 11.487  1.000 56.188  0 24  LEU A CG  1 ? 
ATOM   80   C CD1 . LEU A 1 20  ? 18.314 -21.863 11.022  1.000 52.743  0 24  LEU A CD1 1 ? 
ATOM   81   C CD2 . LEU A 1 20  ? 19.254 -20.659 13.012  1.000 45.903  0 24  LEU A CD2 1 ? 
ATOM   82   N N   . ALA A 1 21  ? 22.904 -18.569 9.297   1.000 62.823  0 25  ALA A N   1 ? 
ATOM   83   C CA  . ALA A 1 21  ? 24.081 -18.675 8.438   1.000 67.532  0 25  ALA A CA  1 ? 
ATOM   84   C C   . ALA A 1 21  ? 25.378 -18.740 9.244   1.000 62.679  0 25  ALA A C   1 ? 
ATOM   85   O O   . ALA A 1 21  ? 26.278 -19.524 8.918   1.000 52.222  0 25  ALA A O   1 ? 
ATOM   86   C CB  . ALA A 1 21  ? 24.115 -17.496 7.459   1.000 64.574  0 25  ALA A CB  1 ? 
ATOM   87   N N   . ASP A 1 22  ? 25.500 -17.914 10.289  1.000 68.150  0 26  ASP A N   1 ? 
ATOM   88   C CA  . ASP A 1 22  ? 26.731 -17.889 11.074  1.000 66.068  0 26  ASP A CA  1 ? 
ATOM   89   C C   . ASP A 1 22  ? 26.947 -19.206 11.793  1.000 61.507  0 26  ASP A C   1 ? 
ATOM   90   O O   . ASP A 1 22  ? 28.062 -19.742 11.800  1.000 59.360  0 26  ASP A O   1 ? 
ATOM   91   C CB  . ASP A 1 22  ? 26.701 -16.740 12.076  1.000 69.945  0 26  ASP A CB  1 ? 
ATOM   92   C CG  . ASP A 1 22  ? 27.139 -15.434 11.465  1.000 87.884  0 26  ASP A CG  1 ? 
ATOM   93   O OD1 . ASP A 1 22  ? 27.575 -15.450 10.288  1.000 94.209  0 26  ASP A OD1 1 ? 
ATOM   94   O OD2 . ASP A 1 22  ? 27.042 -14.395 12.157  1.000 95.096  0 26  ASP A OD2 1 ? 
ATOM   95   N N   . TRP A 1 23  ? 25.894 -19.735 12.413  1.000 58.015  0 27  TRP A N   1 ? 
ATOM   96   C CA  . TRP A 1 23  ? 25.982 -21.066 12.994  1.000 49.403  0 27  TRP A CA  1 ? 
ATOM   97   C C   . TRP A 1 23  ? 26.406 -22.077 11.938  1.000 48.340  0 27  TRP A C   1 ? 
ATOM   98   O O   . TRP A 1 23  ? 27.359 -22.832 12.140  1.000 43.879  0 27  TRP A O   1 ? 
ATOM   99   C CB  . TRP A 1 23  ? 24.643 -21.448 13.628  1.000 40.634  0 27  TRP A CB  1 ? 
ATOM   100  C CG  . TRP A 1 23  ? 24.600 -22.856 14.131  1.000 49.011  0 27  TRP A CG  1 ? 
ATOM   101  C CD1 . TRP A 1 23  ? 25.662 -23.631 14.525  1.000 51.419  0 27  TRP A CD1 1 ? 
ATOM   102  C CD2 . TRP A 1 23  ? 23.431 -23.667 14.298  1.000 49.577  0 27  TRP A CD2 1 ? 
ATOM   103  N NE1 . TRP A 1 23  ? 25.221 -24.876 14.924  1.000 48.922  0 27  TRP A NE1 1 ? 
ATOM   104  C CE2 . TRP A 1 23  ? 23.857 -24.925 14.791  1.000 45.248  0 27  TRP A CE2 1 ? 
ATOM   105  C CE3 . TRP A 1 23  ? 22.063 -23.456 14.073  1.000 45.661  0 27  TRP A CE3 1 ? 
ATOM   106  C CZ2 . TRP A 1 23  ? 22.965 -25.963 15.061  1.000 40.636  0 27  TRP A CZ2 1 ? 
ATOM   107  C CZ3 . TRP A 1 23  ? 21.176 -24.490 14.348  1.000 45.203  0 27  TRP A CZ3 1 ? 
ATOM   108  C CH2 . TRP A 1 23  ? 21.630 -25.726 14.841  1.000 43.603  0 27  TRP A CH2 1 ? 
ATOM   109  N N   . GLY A 1 24  ? 25.730 -22.081 10.785  1.000 49.203  0 28  GLY A N   1 ? 
ATOM   110  C CA  . GLY A 1 24  ? 26.094 -23.017 9.736   1.000 38.857  0 28  GLY A CA  1 ? 
ATOM   111  C C   . GLY A 1 24  ? 27.554 -22.901 9.349   1.000 48.853  0 28  GLY A C   1 ? 
ATOM   112  O O   . GLY A 1 24  ? 28.262 -23.907 9.213   1.000 47.808  0 28  GLY A O   1 ? 
ATOM   113  N N   . ARG A 1 25  ? 28.029 -21.662 9.189   1.000 50.372  0 29  ARG A N   1 ? 
ATOM   114  C CA  . ARG A 1 25  ? 29.412 -21.439 8.786   1.000 47.290  0 29  ARG A CA  1 ? 
ATOM   115  C C   . ARG A 1 25  ? 30.376 -22.002 9.819   1.000 40.115  0 29  ARG A C   1 ? 
ATOM   116  O O   . ARG A 1 25  ? 31.389 -22.611 9.459   1.000 47.914  0 29  ARG A O   1 ? 
ATOM   117  C CB  . ARG A 1 25  ? 29.657 -19.940 8.541   1.000 50.430  0 29  ARG A CB  1 ? 
ATOM   118  C CG  . ARG A 1 25  ? 31.118 -19.567 8.253   1.000 54.551  0 29  ARG A CG  1 ? 
ATOM   119  C CD  . ARG A 1 25  ? 31.692 -20.305 7.043   1.000 59.791  0 29  ARG A CD  1 ? 
ATOM   120  N NE  . ARG A 1 25  ? 30.879 -20.112 5.842   1.000 69.435  0 29  ARG A NE  1 ? 
ATOM   121  C CZ  . ARG A 1 25  ? 31.059 -20.762 4.693   1.000 69.564  0 29  ARG A CZ  1 ? 
ATOM   122  N NH1 . ARG A 1 25  ? 32.019 -21.676 4.582   1.000 54.820  0 29  ARG A NH1 1 ? 
ATOM   123  N NH2 . ARG A 1 25  ? 30.272 -20.500 3.653   1.000 77.383  0 29  ARG A NH2 1 ? 
ATOM   124  N N   . LYS A 1 26  ? 30.043 -21.862 11.109  1.000 46.003  0 30  LYS A N   1 ? 
ATOM   125  C CA  . LYS A 1 26  ? 30.898 -22.392 12.175  1.000 45.713  0 30  LYS A CA  1 ? 
ATOM   126  C C   . LYS A 1 26  ? 31.062 -23.908 12.070  1.000 41.273  0 30  LYS A C   1 ? 
ATOM   127  O O   . LYS A 1 26  ? 32.177 -24.426 12.211  1.000 39.705  0 30  LYS A O   1 ? 
ATOM   128  C CB  . LYS A 1 26  ? 30.344 -22.005 13.547  1.000 39.986  0 30  LYS A CB  1 ? 
ATOM   129  C CG  . LYS A 1 26  ? 30.745 -20.613 14.014  1.000 45.903  0 30  LYS A CG  1 ? 
ATOM   130  C CD  . LYS A 1 26  ? 29.839 -20.124 15.149  1.000 51.488  0 30  LYS A CD  1 ? 
ATOM   131  C CE  . LYS A 1 26  ? 30.296 -18.760 15.699  1.000 48.148  0 30  LYS A CE  1 ? 
ATOM   132  N NZ  . LYS A 1 26  ? 29.397 -18.224 16.792  1.000 46.485  0 30  LYS A NZ  1 ? 
ATOM   133  N N   . GLU A 1 27  ? 29.972 -24.641 11.813  1.000 37.068  0 31  GLU A N   1 ? 
ATOM   134  C CA  . GLU A 1 27  ? 30.112 -26.091 11.681  1.000 46.650  0 31  GLU A CA  1 ? 
ATOM   135  C C   . GLU A 1 27  ? 30.702 -26.482 10.335  1.000 45.858  0 31  GLU A C   1 ? 
ATOM   136  O O   . GLU A 1 27  ? 31.311 -27.553 10.218  1.000 37.833  0 31  GLU A O   1 ? 
ATOM   137  C CB  . GLU A 1 27  ? 28.772 -26.793 11.883  1.000 44.276  0 31  GLU A CB  1 ? 
ATOM   138  C CG  . GLU A 1 27  ? 27.996 -26.266 13.068  1.000 49.761  0 31  GLU A CG  1 ? 
ATOM   139  C CD  . GLU A 1 27  ? 27.102 -27.315 13.678  1.000 57.278  0 31  GLU A CD  1 ? 
ATOM   140  O OE1 . GLU A 1 27  ? 26.602 -28.169 12.911  1.000 63.279  0 31  GLU A OE1 1 ? 
ATOM   141  O OE2 . GLU A 1 27  ? 26.899 -27.286 14.916  1.000 50.496  0 31  GLU A OE2 1 ? 
ATOM   142  N N   . ILE A 1 28  ? 30.548 -25.633 9.320   1.000 38.673  0 32  ILE A N   1 ? 
ATOM   143  C CA  . ILE A 1 28  ? 31.198 -25.918 8.050   1.000 43.610  0 32  ILE A CA  1 ? 
ATOM   144  C C   . ILE A 1 28  ? 32.709 -25.845 8.212   1.000 45.948  0 32  ILE A C   1 ? 
ATOM   145  O O   . ILE A 1 28  ? 33.448 -26.682 7.674   1.000 48.469  0 32  ILE A O   1 ? 
ATOM   146  C CB  . ILE A 1 28  ? 30.687 -24.959 6.955   1.000 48.851  0 32  ILE A CB  1 ? 
ATOM   147  C CG1 . ILE A 1 28  ? 29.249 -25.313 6.565   1.000 48.451  0 32  ILE A CG1 1 ? 
ATOM   148  C CG2 . ILE A 1 28  ? 31.589 -25.002 5.726   1.000 43.889  0 32  ILE A CG2 1 ? 
ATOM   149  C CD1 . ILE A 1 28  ? 28.556 -24.236 5.764   1.000 37.978  0 32  ILE A CD1 1 ? 
ATOM   150  N N   . ALA A 1 29  ? 33.193 -24.856 8.969   1.000 37.781  0 33  ALA A N   1 ? 
ATOM   151  C CA  . ALA A 1 29  ? 34.632 -24.740 9.203   1.000 37.789  0 33  ALA A CA  1 ? 
ATOM   152  C C   . ALA A 1 29  ? 35.171 -25.986 9.890   1.000 38.320  0 33  ALA A C   1 ? 
ATOM   153  O O   . ALA A 1 29  ? 36.190 -26.548 9.476   1.000 45.611  0 33  ALA A O   1 ? 
ATOM   154  C CB  . ALA A 1 29  ? 34.942 -23.493 10.039  1.000 32.791  0 33  ALA A CB  1 ? 
ATOM   155  N N   . ILE A 1 30  ? 34.510 -26.409 10.967  1.000 30.380  0 34  ILE A N   1 ? 
ATOM   156  C CA  . ILE A 1 30  ? 34.836 -27.677 11.605  1.000 39.560  0 34  ILE A CA  1 ? 
ATOM   157  C C   . ILE A 1 30  ? 34.815 -28.825 10.595  1.000 38.294  0 34  ILE A C   1 ? 
ATOM   158  O O   . ILE A 1 30  ? 35.753 -29.627 10.517  1.000 33.801  0 34  ILE A O   1 ? 
ATOM   159  C CB  . ILE A 1 30  ? 33.862 -27.943 12.756  1.000 28.911  0 34  ILE A CB  1 ? 
ATOM   160  C CG1 . ILE A 1 30  ? 33.990 -26.841 13.803  1.000 32.883  0 34  ILE A CG1 1 ? 
ATOM   161  C CG2 . ILE A 1 30  ? 34.112 -29.316 13.295  1.000 27.706  0 34  ILE A CG2 1 ? 
ATOM   162  C CD1 . ILE A 1 30  ? 32.916 -26.876 14.893  1.000 31.193  0 34  ILE A CD1 1 ? 
ATOM   163  N N   . ALA A 1 31  ? 33.740 -28.919 9.807   1.000 34.765  0 35  ALA A N   1 ? 
ATOM   164  C CA  . ALA A 1 31  ? 33.583 -30.053 8.905   1.000 31.991  0 35  ALA A CA  1 ? 
ATOM   165  C C   . ALA A 1 31  ? 34.731 -30.150 7.904   1.000 34.391  0 35  ALA A C   1 ? 
ATOM   166  O O   . ALA A 1 31  ? 35.089 -31.252 7.478   1.000 41.429  0 35  ALA A O   1 ? 
ATOM   167  C CB  . ALA A 1 31  ? 32.239 -29.955 8.181   1.000 32.459  0 35  ALA A CB  1 ? 
ATOM   168  N N   . GLU A 1 32  ? 35.340 -29.019 7.538   1.000 34.165  0 36  GLU A N   1 ? 
ATOM   169  C CA  . GLU A 1 32  ? 36.456 -29.053 6.597   1.000 32.246  0 36  GLU A CA  1 ? 
ATOM   170  C C   . GLU A 1 32  ? 37.655 -29.804 7.154   1.000 33.228  0 36  GLU A C   1 ? 
ATOM   171  O O   . GLU A 1 32  ? 38.405 -30.420 6.386   1.000 32.054  0 36  GLU A O   1 ? 
ATOM   172  C CB  . GLU A 1 32  ? 36.854 -27.635 6.205   1.000 36.460  0 36  GLU A CB  1 ? 
ATOM   173  C CG  . GLU A 1 32  ? 35.829 -26.963 5.296   1.000 50.717  0 36  GLU A CG  1 ? 
ATOM   174  C CD  . GLU A 1 32  ? 35.983 -25.453 5.231   1.000 61.060  0 36  GLU A CD  1 ? 
ATOM   175  O OE1 . GLU A 1 32  ? 35.021 -24.781 4.791   1.000 68.008  0 36  GLU A OE1 1 ? 
ATOM   176  O OE2 . GLU A 1 32  ? 37.062 -24.943 5.615   1.000 56.383  0 36  GLU A OE2 1 ? 
ATOM   177  N N   . THR A 1 33  ? 37.844 -29.786 8.477   1.000 27.906  0 37  THR A N   1 ? 
ATOM   178  C CA  . THR A 1 33  ? 38.945 -30.512 9.092   1.000 26.830  0 37  THR A CA  1 ? 
ATOM   179  C C   . THR A 1 33  ? 38.650 -31.984 9.221   1.000 34.941  0 37  THR A C   1 ? 
ATOM   180  O O   . THR A 1 33  ? 39.541 -32.755 9.605   1.000 37.302  0 37  THR A O   1 ? 
ATOM   181  C CB  . THR A 1 33  ? 39.260 -29.961 10.476  1.000 26.419  0 37  THR A CB  1 ? 
ATOM   182  O OG1 . THR A 1 33  ? 38.360 -30.548 11.424  1.000 25.966  0 37  THR A OG1 1 ? 
ATOM   183  C CG2 . THR A 1 33  ? 39.121 -28.449 10.501  1.000 27.353  0 37  THR A CG2 1 ? 
ATOM   184  N N   . GLU A 1 34  ? 37.416 -32.373 8.926   1.000 30.885  0 38  GLU A N   1 ? 
ATOM   185  C CA  . GLU A 1 34  ? 36.974 -33.751 8.948   1.000 30.340  0 38  GLU A CA  1 ? 
ATOM   186  C C   . GLU A 1 34  ? 36.866 -34.335 7.547   1.000 38.939  0 38  GLU A C   1 ? 
ATOM   187  O O   . GLU A 1 34  ? 36.617 -35.537 7.405   1.000 36.731  0 38  GLU A O   1 ? 
ATOM   188  C CB  . GLU A 1 34  ? 35.614 -33.835 9.655   1.000 30.991  0 38  GLU A CB  1 ? 
ATOM   189  C CG  . GLU A 1 34  ? 35.699 -33.853 11.157  1.000 33.346  0 38  GLU A CG  1 ? 
ATOM   190  C CD  . GLU A 1 34  ? 36.441 -35.081 11.675  1.000 38.331  0 38  GLU A CD  1 ? 
ATOM   191  O OE1 . GLU A 1 34  ? 37.620 -34.942 12.093  1.000 36.412  0 38  GLU A OE1 1 ? 
ATOM   192  O OE2 . GLU A 1 34  ? 35.839 -36.183 11.671  1.000 29.914  0 38  GLU A OE2 1 ? 
ATOM   193  N N   . MET A 1 35  ? 37.049 -33.511 6.512   1.000 37.686  0 39  MET A N   1 ? 
ATOM   194  C CA  . MET A 1 35  ? 36.783 -33.895 5.131   1.000 36.552  0 39  MET A CA  1 ? 
ATOM   195  C C   . MET A 1 35  ? 38.031 -33.682 4.289   1.000 37.333  0 39  MET A C   1 ? 
ATOM   196  O O   . MET A 1 35  ? 38.047 -32.841 3.381   1.000 37.362  0 39  MET A O   1 ? 
ATOM   197  C CB  . MET A 1 35  ? 35.604 -33.107 4.568   1.000 31.412  0 39  MET A CB  1 ? 
ATOM   198  C CG  . MET A 1 35  ? 34.339 -33.292 5.375   1.000 29.140  0 39  MET A CG  1 ? 
ATOM   199  S SD  . MET A 1 35  ? 32.985 -32.413 4.610   1.000 34.573  0 39  MET A SD  1 ? 
ATOM   200  C CE  . MET A 1 35  ? 32.231 -33.761 3.709   1.000 33.293  0 39  MET A CE  1 ? 
ATOM   201  N N   . PRO A 1 36  ? 39.092 -34.449 4.552   1.000 40.571  0 40  PRO A N   1 ? 
ATOM   202  C CA  . PRO A 1 36  ? 40.360 -34.192 3.850   1.000 35.428  0 40  PRO A CA  1 ? 
ATOM   203  C C   . PRO A 1 36  ? 40.260 -34.409 2.354   1.000 39.586  0 40  PRO A C   1 ? 
ATOM   204  O O   . PRO A 1 36  ? 41.003 -33.772 1.597   1.000 40.257  0 40  PRO A O   1 ? 
ATOM   205  C CB  . PRO A 1 36  ? 41.337 -35.175 4.513   1.000 33.665  0 40  PRO A CB  1 ? 
ATOM   206  C CG  . PRO A 1 36  ? 40.445 -36.259 5.099   1.000 43.039  0 40  PRO A CG  1 ? 
ATOM   207  C CD  . PRO A 1 36  ? 39.171 -35.591 5.482   1.000 25.956  0 40  PRO A CD  1 ? 
ATOM   208  N N   . GLY A 1 37  ? 39.345 -35.273 1.910   1.000 35.215  0 41  GLY A N   1 ? 
ATOM   209  C CA  . GLY A 1 37  ? 39.220 -35.541 0.490   1.000 28.896  0 41  GLY A CA  1 ? 
ATOM   210  C C   . GLY A 1 37  ? 38.861 -34.298 -0.292  1.000 40.923  0 41  GLY A C   1 ? 
ATOM   211  O O   . GLY A 1 37  ? 39.491 -33.980 -1.304  1.000 47.816  0 41  GLY A O   1 ? 
ATOM   212  N N   . LEU A 1 38  ? 37.864 -33.558 0.184   1.000 39.915  0 42  LEU A N   1 ? 
ATOM   213  C CA  . LEU A 1 38  ? 37.447 -32.368 -0.548  1.000 44.747  0 42  LEU A CA  1 ? 
ATOM   214  C C   . LEU A 1 38  ? 38.470 -31.252 -0.404  1.000 40.921  0 42  LEU A C   1 ? 
ATOM   215  O O   . LEU A 1 38  ? 38.765 -30.546 -1.375  1.000 47.092  0 42  LEU A O   1 ? 
ATOM   216  C CB  . LEU A 1 38  ? 36.061 -31.910 -0.087  1.000 42.568  0 42  LEU A CB  1 ? 
ATOM   217  C CG  . LEU A 1 38  ? 34.938 -32.936 -0.299  1.000 41.352  0 42  LEU A CG  1 ? 
ATOM   218  C CD1 . LEU A 1 38  ? 33.702 -32.617 0.556   1.000 40.052  0 42  LEU A CD1 1 ? 
ATOM   219  C CD2 . LEU A 1 38  ? 34.563 -33.070 -1.769  1.000 33.515  0 42  LEU A CD2 1 ? 
ATOM   220  N N   . MET A 1 39  ? 39.032 -31.081 0.789   1.000 40.415  0 43  MET A N   1 ? 
ATOM   221  C CA  . MET A 1 39  ? 40.072 -30.068 0.952   1.000 42.850  0 43  MET A CA  1 ? 
ATOM   222  C C   . MET A 1 39  ? 41.258 -30.366 0.046   1.000 46.764  0 43  MET A C   1 ? 
ATOM   223  O O   . MET A 1 39  ? 41.850 -29.453 -0.542  1.000 48.348  0 43  MET A O   1 ? 
ATOM   224  C CB  . MET A 1 39  ? 40.512 -29.983 2.413   1.000 30.430  0 43  MET A CB  1 ? 
ATOM   225  C CG  . MET A 1 39  ? 39.420 -29.547 3.360   1.000 37.928  0 43  MET A CG  1 ? 
ATOM   226  S SD  . MET A 1 39  ? 38.577 -28.034 2.841   1.000 49.540  0 43  MET A SD  1 ? 
ATOM   227  C CE  . MET A 1 39  ? 37.034 -28.716 2.308   1.000 56.791  0 43  MET A CE  1 ? 
ATOM   228  N N   . ALA A 1 40  ? 41.603 -31.648 -0.098  1.000 42.834  0 44  ALA A N   1 ? 
ATOM   229  C CA  . ALA A 1 40  ? 42.712 -32.001 -0.968  1.000 34.838  0 44  ALA A CA  1 ? 
ATOM   230  C C   . ALA A 1 40  ? 42.347 -31.759 -2.420  1.000 40.178  0 44  ALA A C   1 ? 
ATOM   231  O O   . ALA A 1 40  ? 43.200 -31.326 -3.207  1.000 42.363  0 44  ALA A O   1 ? 
ATOM   232  C CB  . ALA A 1 40  ? 43.128 -33.456 -0.748  1.000 30.172  0 44  ALA A CB  1 ? 
ATOM   233  N N   . LEU A 1 41  ? 41.085 -32.033 -2.791  1.000 39.784  0 45  LEU A N   1 ? 
ATOM   234  C CA  . LEU A 1 41  ? 40.624 -31.752 -4.149  1.000 34.009  0 45  LEU A CA  1 ? 
ATOM   235  C C   . LEU A 1 41  ? 40.654 -30.266 -4.416  1.000 42.031  0 45  LEU A C   1 ? 
ATOM   236  O O   . LEU A 1 41  ? 41.041 -29.831 -5.505  1.000 46.769  0 45  LEU A O   1 ? 
ATOM   237  C CB  . LEU A 1 41  ? 39.213 -32.288 -4.379  1.000 39.844  0 45  LEU A CB  1 ? 
ATOM   238  C CG  . LEU A 1 41  ? 39.083 -33.776 -4.714  1.000 48.622  0 45  LEU A CG  1 ? 
ATOM   239  C CD1 . LEU A 1 41  ? 37.673 -34.120 -5.193  1.000 46.463  0 45  LEU A CD1 1 ? 
ATOM   240  C CD2 . LEU A 1 41  ? 40.137 -34.193 -5.740  1.000 47.858  0 45  LEU A CD2 1 ? 
ATOM   241  N N   . ARG A 1 42  ? 40.253 -29.467 -3.428  1.000 49.327  0 46  ARG A N   1 ? 
ATOM   242  C CA  . ARG A 1 42  ? 40.434 -28.026 -3.542  1.000 58.389  0 46  ARG A CA  1 ? 
ATOM   243  C C   . ARG A 1 42  ? 41.888 -27.703 -3.843  1.000 57.049  0 46  ARG A C   1 ? 
ATOM   244  O O   . ARG A 1 42  ? 42.207 -27.111 -4.876  1.000 54.320  0 46  ARG A O   1 ? 
ATOM   245  C CB  . ARG A 1 42  ? 39.978 -27.329 -2.260  1.000 48.279  0 46  ARG A CB  1 ? 
ATOM   246  C CG  . ARG A 1 42  ? 38.484 -27.176 -2.173  1.000 42.392  0 46  ARG A CG  1 ? 
ATOM   247  C CD  . ARG A 1 42  ? 38.040 -26.510 -0.879  1.000 41.613  0 46  ARG A CD  1 ? 
ATOM   248  N NE  . ARG A 1 42  ? 36.648 -26.859 -0.572  1.000 42.310  0 46  ARG A NE  1 ? 
ATOM   249  C CZ  . ARG A 1 42  ? 35.880 -26.192 0.282   1.000 41.981  0 46  ARG A CZ  1 ? 
ATOM   250  N NH1 . ARG A 1 42  ? 36.357 -25.131 0.921   1.000 43.768  0 46  ARG A NH1 1 ? 
ATOM   251  N NH2 . ARG A 1 42  ? 34.635 -26.586 0.499   1.000 44.913  0 46  ARG A NH2 1 ? 
ATOM   252  N N   . GLU A 1 43  ? 42.786 -28.139 -2.961  1.000 53.093  0 47  GLU A N   1 ? 
ATOM   253  C CA  . GLU A 1 43  ? 44.203 -27.838 -3.116  1.000 56.304  0 47  GLU A CA  1 ? 
ATOM   254  C C   . GLU A 1 43  ? 44.735 -28.225 -4.494  1.000 61.278  0 47  GLU A C   1 ? 
ATOM   255  O O   . GLU A 1 43  ? 45.576 -27.520 -5.067  1.000 64.745  0 47  GLU A O   1 ? 
ATOM   256  C CB  . GLU A 1 43  ? 44.989 -28.549 -2.029  1.000 47.327  0 47  GLU A CB  1 ? 
ATOM   257  C CG  . GLU A 1 43  ? 46.420 -28.159 -2.023  1.000 70.119  0 47  GLU A CG  1 ? 
ATOM   258  C CD  . GLU A 1 43  ? 46.846 -27.707 -0.662  1.000 92.237  0 47  GLU A CD  1 ? 
ATOM   259  O OE1 . GLU A 1 43  ? 47.953 -28.090 -0.232  1.000 100.757 0 47  GLU A OE1 1 ? 
ATOM   260  O OE2 . GLU A 1 43  ? 46.057 -26.986 -0.013  1.000 96.683  0 47  GLU A OE2 1 ? 
ATOM   261  N N   . GLU A 1 44  ? 44.254 -29.334 -5.053  1.000 55.986  0 48  GLU A N   1 ? 
ATOM   262  C CA  . GLU A 1 44  ? 44.797 -29.772 -6.333  1.000 61.521  0 48  GLU A CA  1 ? 
ATOM   263  C C   . GLU A 1 44  ? 44.217 -28.968 -7.495  1.000 66.205  0 48  GLU A C   1 ? 
ATOM   264  O O   . GLU A 1 44  ? 44.965 -28.469 -8.343  1.000 69.127  0 48  GLU A O   1 ? 
ATOM   265  C CB  . GLU A 1 44  ? 44.544 -31.269 -6.533  1.000 52.043  0 48  GLU A CB  1 ? 
ATOM   266  C CG  . GLU A 1 44  ? 45.078 -31.807 -7.846  1.000 61.518  0 48  GLU A CG  1 ? 
ATOM   267  C CD  . GLU A 1 44  ? 44.831 -33.295 -8.031  1.000 73.388  0 48  GLU A CD  1 ? 
ATOM   268  O OE1 . GLU A 1 44  ? 44.903 -33.778 -9.188  1.000 74.448  0 48  GLU A OE1 1 ? 
ATOM   269  O OE2 . GLU A 1 44  ? 44.561 -33.982 -7.021  1.000 77.751  0 48  GLU A OE2 1 ? 
ATOM   270  N N   . PHE A 1 45  ? 42.891 -28.810 -7.533  1.000 64.223  0 49  PHE A N   1 ? 
ATOM   271  C CA  . PHE A 1 45  ? 42.188 -28.305 -8.706  1.000 64.026  0 49  PHE A CA  1 ? 
ATOM   272  C C   . PHE A 1 45  ? 41.708 -26.864 -8.587  1.000 72.888  0 49  PHE A C   1 ? 
ATOM   273  O O   . PHE A 1 45  ? 41.045 -26.381 -9.514  1.000 76.033  0 49  PHE A O   1 ? 
ATOM   274  C CB  . PHE A 1 45  ? 40.977 -29.192 -9.017  1.000 56.891  0 49  PHE A CB  1 ? 
ATOM   275  C CG  . PHE A 1 45  ? 41.332 -30.593 -9.368  1.000 60.181  0 49  PHE A CG  1 ? 
ATOM   276  C CD1 . PHE A 1 45  ? 41.737 -30.918 -10.649 1.000 58.789  0 49  PHE A CD1 1 ? 
ATOM   277  C CD2 . PHE A 1 45  ? 41.253 -31.598 -8.421  1.000 64.087  0 49  PHE A CD2 1 ? 
ATOM   278  C CE1 . PHE A 1 45  ? 42.063 -32.222 -10.989 1.000 55.578  0 49  PHE A CE1 1 ? 
ATOM   279  C CE2 . PHE A 1 45  ? 41.577 -32.902 -8.752  1.000 66.492  0 49  PHE A CE2 1 ? 
ATOM   280  C CZ  . PHE A 1 45  ? 41.986 -33.210 -10.042 1.000 62.700  0 49  PHE A CZ  1 ? 
ATOM   281  N N   . SER A 1 46  ? 42.010 -26.161 -7.488  1.000 73.962  0 50  SER A N   1 ? 
ATOM   282  C CA  . SER A 1 46  ? 41.456 -24.818 -7.310  1.000 74.717  0 50  SER A CA  1 ? 
ATOM   283  C C   . SER A 1 46  ? 42.019 -23.834 -8.324  1.000 77.141  0 50  SER A C   1 ? 
ATOM   284  O O   . SER A 1 46  ? 41.304 -22.918 -8.751  1.000 72.206  0 50  SER A O   1 ? 
ATOM   285  C CB  . SER A 1 46  ? 41.719 -24.303 -5.895  1.000 78.899  0 50  SER A CB  1 ? 
ATOM   286  O OG  . SER A 1 46  ? 43.066 -23.882 -5.752  1.000 86.979  0 50  SER A OG  1 ? 
ATOM   287  N N   . ALA A 1 47  ? 43.289 -23.996 -8.713  1.000 80.704  0 51  ALA A N   1 ? 
ATOM   288  C CA  . ALA A 1 47  ? 43.880 -23.120 -9.726  1.000 74.893  0 51  ALA A CA  1 ? 
ATOM   289  C C   . ALA A 1 47  ? 43.258 -23.372 -11.097 1.000 67.121  0 51  ALA A C   1 ? 
ATOM   290  O O   . ALA A 1 47  ? 42.636 -22.484 -11.690 1.000 58.215  0 51  ALA A O   1 ? 
ATOM   291  C CB  . ALA A 1 47  ? 45.400 -23.317 -9.782  1.000 67.798  0 51  ALA A CB  1 ? 
ATOM   292  N N   . LYS A 1 48  ? 43.410 -24.595 -11.607 1.000 71.048  0 52  LYS A N   1 ? 
ATOM   293  C CA  . LYS A 1 48  ? 42.934 -24.930 -12.946 1.000 77.478  0 52  LYS A CA  1 ? 
ATOM   294  C C   . LYS A 1 48  ? 41.436 -24.700 -13.106 1.000 74.417  0 52  LYS A C   1 ? 
ATOM   295  O O   . LYS A 1 48  ? 40.972 -24.328 -14.190 1.000 83.365  0 52  LYS A O   1 ? 
ATOM   296  C CB  . LYS A 1 48  ? 43.270 -26.381 -13.266 1.000 83.018  0 52  LYS A CB  1 ? 
ATOM   297  C CG  . LYS A 1 48  ? 44.716 -26.769 -12.978 1.000 85.252  0 52  LYS A CG  1 ? 
ATOM   298  C CD  . LYS A 1 48  ? 45.315 -27.569 -14.139 1.000 88.058  0 52  LYS A CD  1 ? 
ATOM   299  C CE  . LYS A 1 48  ? 45.827 -26.668 -15.286 1.000 84.905  0 52  LYS A CE  1 ? 
ATOM   300  N NZ  . LYS A 1 48  ? 46.153 -27.410 -16.546 1.000 76.635  0 52  LYS A NZ  1 ? 
ATOM   301  N N   . LYS A 1 49  ? 40.668 -24.922 -12.046 1.000 68.040  0 53  LYS A N   1 ? 
ATOM   302  C CA  . LYS A 1 49  ? 39.209 -24.893 -12.074 1.000 64.792  0 53  LYS A CA  1 ? 
ATOM   303  C C   . LYS A 1 49  ? 38.683 -25.800 -13.179 1.000 61.136  0 53  LYS A C   1 ? 
ATOM   304  O O   . LYS A 1 49  ? 38.176 -25.304 -14.191 1.000 50.351  0 53  LYS A O   1 ? 
ATOM   305  C CB  . LYS A 1 49  ? 38.693 -23.468 -12.269 1.000 72.751  0 53  LYS A CB  1 ? 
ATOM   306  C CG  . LYS A 1 49  ? 39.364 -22.439 -11.370 1.000 78.591  0 53  LYS A CG  1 ? 
ATOM   307  C CD  . LYS A 1 49  ? 38.394 -21.345 -10.937 1.000 75.377  0 53  LYS A CD  1 ? 
ATOM   308  C CE  . LYS A 1 49  ? 38.805 -20.757 -9.594  1.000 68.011  0 53  LYS A CE  1 ? 
ATOM   309  N NZ  . LYS A 1 49  ? 37.877 -21.144 -8.501  1.000 68.237  0 53  LYS A NZ  1 ? 
ATOM   310  N N   . PRO A 1 50  ? 38.771 -27.126 -13.018 1.000 66.671  0 54  PRO A N   1 ? 
ATOM   311  C CA  . PRO A 1 50  ? 38.284 -28.031 -14.075 1.000 70.543  0 54  PRO A CA  1 ? 
ATOM   312  C C   . PRO A 1 50  ? 36.785 -27.943 -14.322 1.000 72.998  0 54  PRO A C   1 ? 
ATOM   313  O O   . PRO A 1 50  ? 36.312 -28.422 -15.364 1.000 64.668  0 54  PRO A O   1 ? 
ATOM   314  C CB  . PRO A 1 50  ? 38.674 -29.422 -13.553 1.000 64.471  0 54  PRO A CB  1 ? 
ATOM   315  C CG  . PRO A 1 50  ? 38.694 -29.263 -12.075 1.000 61.702  0 54  PRO A CG  1 ? 
ATOM   316  C CD  . PRO A 1 50  ? 39.237 -27.871 -11.838 1.000 63.534  0 54  PRO A CD  1 ? 
ATOM   317  N N   . LEU A 1 51  ? 36.021 -27.349 -13.407 1.000 70.303  0 55  LEU A N   1 ? 
ATOM   318  C CA  . LEU A 1 51  ? 34.576 -27.278 -13.542 1.000 68.479  0 55  LEU A CA  1 ? 
ATOM   319  C C   . LEU A 1 51  ? 34.084 -25.892 -13.971 1.000 73.943  0 55  LEU A C   1 ? 
ATOM   320  O O   . LEU A 1 51  ? 32.880 -25.616 -13.885 1.000 71.066  0 55  LEU A O   1 ? 
ATOM   321  C CB  . LEU A 1 51  ? 33.915 -27.709 -12.229 1.000 69.437  0 55  LEU A CB  1 ? 
ATOM   322  C CG  . LEU A 1 51  ? 34.105 -29.157 -11.753 1.000 57.820  0 55  LEU A CG  1 ? 
ATOM   323  C CD1 . LEU A 1 51  ? 33.435 -29.321 -10.425 1.000 48.335  0 55  LEU A CD1 1 ? 
ATOM   324  C CD2 . LEU A 1 51  ? 33.545 -30.173 -12.742 1.000 64.095  0 55  LEU A CD2 1 ? 
ATOM   325  N N   . GLN A 1 52  ? 34.978 -25.020 -14.437 1.000 82.781  0 56  GLN A N   1 ? 
ATOM   326  C CA  . GLN A 1 52  ? 34.546 -23.749 -15.008 1.000 87.324  0 56  GLN A CA  1 ? 
ATOM   327  C C   . GLN A 1 52  ? 33.633 -24.000 -16.204 1.000 76.499  0 56  GLN A C   1 ? 
ATOM   328  O O   . GLN A 1 52  ? 33.998 -24.716 -17.138 1.000 76.054  0 56  GLN A O   1 ? 
ATOM   329  C CB  . GLN A 1 52  ? 35.762 -22.916 -15.423 1.000 92.861  0 56  GLN A CB  1 ? 
ATOM   330  C CG  . GLN A 1 52  ? 35.429 -21.475 -15.758 1.000 97.959  0 56  GLN A CG  1 ? 
ATOM   331  C CD  . GLN A 1 52  ? 34.694 -20.780 -14.631 1.000 102.604 0 56  GLN A CD  1 ? 
ATOM   332  O OE1 . GLN A 1 52  ? 33.562 -20.319 -14.798 1.000 103.318 0 56  GLN A OE1 1 ? 
ATOM   333  N NE2 . GLN A 1 52  ? 35.333 -20.702 -13.472 1.000 104.942 0 56  GLN A NE2 1 ? 
ATOM   334  N N   . GLY A 1 53  ? 32.434 -23.425 -16.169 1.000 71.835  0 57  GLY A N   1 ? 
ATOM   335  C CA  . GLY A 1 53  ? 31.443 -23.660 -17.203 1.000 73.314  0 57  GLY A CA  1 ? 
ATOM   336  C C   . GLY A 1 53  ? 30.413 -24.716 -16.860 1.000 74.106  0 57  GLY A C   1 ? 
ATOM   337  O O   . GLY A 1 53  ? 29.463 -24.918 -17.638 1.000 58.778  0 57  GLY A O   1 ? 
ATOM   338  N N   . ALA A 1 54  ? 30.573 -25.393 -15.722 1.000 79.433  0 58  ALA A N   1 ? 
ATOM   339  C CA  . ALA A 1 54  ? 29.629 -26.413 -15.298 1.000 82.376  0 58  ALA A CA  1 ? 
ATOM   340  C C   . ALA A 1 54  ? 28.441 -25.779 -14.586 1.000 76.812  0 58  ALA A C   1 ? 
ATOM   341  O O   . ALA A 1 54  ? 28.570 -24.778 -13.874 1.000 72.261  0 58  ALA A O   1 ? 
ATOM   342  C CB  . ALA A 1 54  ? 30.304 -27.432 -14.380 1.000 77.686  0 58  ALA A CB  1 ? 
ATOM   343  N N   . ARG A 1 55  ? 27.280 -26.379 -14.788 1.000 69.566  0 59  ARG A N   1 ? 
ATOM   344  C CA  . ARG A 1 55  ? 26.025 -25.892 -14.237 1.000 69.627  0 59  ARG A CA  1 ? 
ATOM   345  C C   . ARG A 1 55  ? 25.351 -27.127 -13.645 1.000 64.302  0 59  ARG A C   1 ? 
ATOM   346  O O   . ARG A 1 55  ? 24.855 -27.979 -14.386 1.000 69.014  0 59  ARG A O   1 ? 
ATOM   347  C CB  . ARG A 1 55  ? 25.197 -25.217 -15.328 1.000 76.846  0 59  ARG A CB  1 ? 
ATOM   348  C CG  . ARG A 1 55  ? 25.683 -23.794 -15.639 1.000 81.028  0 59  ARG A CG  1 ? 
ATOM   349  C CD  . ARG A 1 55  ? 25.040 -23.182 -16.876 1.000 75.114  0 59  ARG A CD  1 ? 
ATOM   350  N NE  . ARG A 1 55  ? 25.863 -23.299 -18.080 1.000 82.470  0 59  ARG A NE  1 ? 
ATOM   351  C CZ  . ARG A 1 55  ? 25.565 -24.057 -19.137 1.000 87.855  0 59  ARG A CZ  1 ? 
ATOM   352  N NH1 . ARG A 1 55  ? 24.470 -24.796 -19.139 1.000 88.153  0 59  ARG A NH1 1 ? 
ATOM   353  N NH2 . ARG A 1 55  ? 26.364 -24.083 -20.199 1.000 87.913  0 59  ARG A NH2 1 ? 
ATOM   354  N N   . ILE A 1 56  ? 25.375 -27.259 -12.320 1.000 59.936  0 60  ILE A N   1 ? 
ATOM   355  C CA  . ILE A 1 56  ? 25.024 -28.511 -11.648 1.000 61.247  0 60  ILE A CA  1 ? 
ATOM   356  C C   . ILE A 1 56  ? 23.713 -28.324 -10.902 1.000 56.188  0 60  ILE A C   1 ? 
ATOM   357  O O   . ILE A 1 56  ? 23.615 -27.473 -10.009 1.000 58.823  0 60  ILE A O   1 ? 
ATOM   358  C CB  . ILE A 1 56  ? 26.127 -28.980 -10.683 1.000 57.086  0 60  ILE A CB  1 ? 
ATOM   359  C CG1 . ILE A 1 56  ? 27.507 -28.789 -11.310 1.000 50.322  0 60  ILE A CG1 1 ? 
ATOM   360  C CG2 . ILE A 1 56  ? 25.898 -30.449 -10.274 1.000 56.402  0 60  ILE A CG2 1 ? 
ATOM   361  C CD1 . ILE A 1 56  ? 28.610 -29.467 -10.562 1.000 51.456  0 60  ILE A CD1 1 ? 
ATOM   362  N N   . ALA A 1 57  ? 22.713 -29.128 -11.259 1.000 53.520  0 61  ALA A N   1 ? 
ATOM   363  C CA  . ALA A 1 57  ? 21.502 -29.259 -10.460 1.000 57.765  0 61  ALA A CA  1 ? 
ATOM   364  C C   . ALA A 1 57  ? 21.758 -30.338 -9.404  1.000 55.467  0 61  ALA A C   1 ? 
ATOM   365  O O   . ALA A 1 57  ? 21.921 -31.519 -9.735  1.000 54.299  0 61  ALA A O   1 ? 
ATOM   366  C CB  . ALA A 1 57  ? 20.293 -29.584 -11.338 1.000 50.998  0 61  ALA A CB  1 ? 
ATOM   367  N N   . GLY A 1 58  ? 21.829 -29.927 -8.142  1.000 46.906  0 62  GLY A N   1 ? 
ATOM   368  C CA  . GLY A 1 58  ? 22.038 -30.844 -7.036  1.000 50.696  0 62  GLY A CA  1 ? 
ATOM   369  C C   . GLY A 1 58  ? 20.724 -31.231 -6.382  1.000 57.815  0 62  GLY A C   1 ? 
ATOM   370  O O   . GLY A 1 58  ? 19.837 -30.397 -6.196  1.000 59.852  0 62  GLY A O   1 ? 
ATOM   371  N N   . CYS A 1 59  ? 20.608 -32.518 -6.048  1.000 58.939  0 63  CYS A N   1 ? 
ATOM   372  C CA  . CYS A 1 59  ? 19.456 -33.058 -5.317  1.000 61.797  0 63  CYS A CA  1 ? 
ATOM   373  C C   . CYS A 1 59  ? 20.017 -34.109 -4.356  1.000 59.265  0 63  CYS A C   1 ? 
ATOM   374  O O   . CYS A 1 59  ? 20.066 -35.305 -4.655  1.000 56.025  0 63  CYS A O   1 ? 
ATOM   375  C CB  . CYS A 1 59  ? 18.393 -33.637 -6.248  1.000 60.570  0 63  CYS A CB  1 ? 
ATOM   376  S SG  . CYS A 1 59  ? 16.944 -34.316 -5.382  1.000 60.310  0 63  CYS A SG  1 ? 
ATOM   377  N N   . LEU A 1 60  ? 20.455 -33.636 -3.193  1.000 56.838  0 64  LEU A N   1 ? 
ATOM   378  C CA  . LEU A 1 60  ? 21.178 -34.445 -2.222  1.000 53.725  0 64  LEU A CA  1 ? 
ATOM   379  C C   . LEU A 1 60  ? 21.024 -33.775 -0.868  1.000 53.209  0 64  LEU A C   1 ? 
ATOM   380  O O   . LEU A 1 60  ? 21.195 -32.556 -0.770  1.000 40.060  0 64  LEU A O   1 ? 
ATOM   381  C CB  . LEU A 1 60  ? 22.666 -34.568 -2.597  1.000 54.372  0 64  LEU A CB  1 ? 
ATOM   382  C CG  . LEU A 1 60  ? 23.492 -35.683 -1.970  1.000 46.408  0 64  LEU A CG  1 ? 
ATOM   383  C CD1 . LEU A 1 60  ? 24.558 -36.211 -2.930  1.000 43.208  0 64  LEU A CD1 1 ? 
ATOM   384  C CD2 . LEU A 1 60  ? 24.119 -35.181 -0.691  1.000 53.425  0 64  LEU A CD2 1 ? 
ATOM   385  N N   . HIS A 1 61  ? 20.708 -34.574 0.157   1.000 53.375  0 65  HIS A N   1 ? 
ATOM   386  C CA  . HIS A 1 61  ? 20.489 -34.105 1.520   1.000 55.951  0 65  HIS A CA  1 ? 
ATOM   387  C C   . HIS A 1 61  ? 21.281 -32.843 1.826   1.000 52.425  0 65  HIS A C   1 ? 
ATOM   388  O O   . HIS A 1 61  ? 22.512 -32.862 1.797   1.000 55.538  0 65  HIS A O   1 ? 
ATOM   389  C CB  . HIS A 1 61  ? 20.871 -35.194 2.515   1.000 63.200  0 65  HIS A CB  1 ? 
ATOM   390  C CG  . HIS A 1 61  ? 20.415 -36.564 2.126   1.000 70.964  0 65  HIS A CG  1 ? 
ATOM   391  N ND1 . HIS A 1 61  ? 19.115 -36.992 2.292   1.000 73.575  0 65  HIS A ND1 1 ? 
ATOM   392  C CD2 . HIS A 1 61  ? 21.094 -37.616 1.613   1.000 72.514  0 65  HIS A CD2 1 ? 
ATOM   393  C CE1 . HIS A 1 61  ? 19.011 -38.245 1.887   1.000 70.140  0 65  HIS A CE1 1 ? 
ATOM   394  N NE2 . HIS A 1 61  ? 20.197 -38.647 1.470   1.000 70.956  0 65  HIS A NE2 1 ? 
ATOM   395  N N   . MET A 1 62  ? 20.592 -31.732 2.074   1.000 52.835  0 66  MET A N   1 ? 
ATOM   396  C CA  . MET A 1 62  ? 21.261 -30.452 2.298   1.000 52.685  0 66  MET A CA  1 ? 
ATOM   397  C C   . MET A 1 62  ? 21.720 -30.411 3.756   1.000 49.551  0 66  MET A C   1 ? 
ATOM   398  O O   . MET A 1 62  ? 21.051 -29.889 4.654   1.000 49.456  0 66  MET A O   1 ? 
ATOM   399  C CB  . MET A 1 62  ? 20.348 -29.285 1.942   1.000 50.269  0 66  MET A CB  1 ? 
ATOM   400  C CG  . MET A 1 62  ? 20.959 -27.923 2.208   1.000 52.733  0 66  MET A CG  1 ? 
ATOM   401  S SD  . MET A 1 62  ? 22.363 -27.507 1.147   1.000 55.557  0 66  MET A SD  1 ? 
ATOM   402  C CE  . MET A 1 62  ? 23.714 -27.895 2.264   1.000 53.512  0 66  MET A CE  1 ? 
ATOM   403  N N   . ALA A 1 63  ? 22.891 -30.993 3.982   1.000 38.070  0 67  ALA A N   1 ? 
ATOM   404  C CA  . ALA A 1 63  ? 23.524 -31.075 5.286   1.000 42.974  0 67  ALA A CA  1 ? 
ATOM   405  C C   . ALA A 1 63  ? 24.836 -30.289 5.285   1.000 48.427  0 67  ALA A C   1 ? 
ATOM   406  O O   . ALA A 1 63  ? 25.282 -29.758 4.261   1.000 54.209  0 67  ALA A O   1 ? 
ATOM   407  C CB  . ALA A 1 63  ? 23.755 -32.542 5.674   1.000 34.780  0 67  ALA A CB  1 ? 
ATOM   408  N N   . ILE A 1 64  ? 25.451 -30.208 6.462   1.000 47.461  0 68  ILE A N   1 ? 
ATOM   409  C CA  . ILE A 1 64  ? 26.705 -29.469 6.607   1.000 48.345  0 68  ILE A CA  1 ? 
ATOM   410  C C   . ILE A 1 64  ? 27.793 -30.086 5.727   1.000 45.524  0 68  ILE A C   1 ? 
ATOM   411  O O   . ILE A 1 64  ? 28.498 -29.377 4.992   1.000 46.169  0 68  ILE A O   1 ? 
ATOM   412  C CB  . ILE A 1 64  ? 27.115 -29.415 8.093   1.000 41.213  0 68  ILE A CB  1 ? 
ATOM   413  C CG1 . ILE A 1 64  ? 26.281 -28.372 8.834   1.000 38.707  0 68  ILE A CG1 1 ? 
ATOM   414  C CG2 . ILE A 1 64  ? 28.600 -29.138 8.262   1.000 36.712  0 68  ILE A CG2 1 ? 
ATOM   415  C CD1 . ILE A 1 64  ? 26.818 -26.958 8.696   1.000 45.274  0 68  ILE A CD1 1 ? 
ATOM   416  N N   . ALA A 1 65  ? 27.939 -31.416 5.777   1.000 33.896  0 69  ALA A N   1 ? 
ATOM   417  C CA  . ALA A 1 65  ? 28.877 -32.084 4.875   1.000 32.257  0 69  ALA A CA  1 ? 
ATOM   418  C C   . ALA A 1 65  ? 28.609 -31.701 3.429   1.000 46.119  0 69  ALA A C   1 ? 
ATOM   419  O O   . ALA A 1 65  ? 29.540 -31.462 2.650   1.000 54.962  0 69  ALA A O   1 ? 
ATOM   420  C CB  . ALA A 1 65  ? 28.788 -33.600 5.033   1.000 31.259  0 69  ALA A CB  1 ? 
ATOM   421  N N   . THR A 1 66  ? 27.336 -31.614 3.060   1.000 38.323  0 70  THR A N   1 ? 
ATOM   422  C CA  . THR A 1 66  ? 26.995 -31.257 1.696   1.000 39.773  0 70  THR A CA  1 ? 
ATOM   423  C C   . THR A 1 66  ? 27.344 -29.810 1.408   1.000 40.431  0 70  THR A C   1 ? 
ATOM   424  O O   . THR A 1 66  ? 27.615 -29.454 0.258   1.000 37.499  0 70  THR A O   1 ? 
ATOM   425  C CB  . THR A 1 66  ? 25.508 -31.523 1.451   1.000 48.872  0 70  THR A CB  1 ? 
ATOM   426  O OG1 . THR A 1 66  ? 25.151 -32.772 2.056   1.000 54.851  0 70  THR A OG1 1 ? 
ATOM   427  C CG2 . THR A 1 66  ? 25.214 -31.606 -0.016  1.000 37.531  0 70  THR A CG2 1 ? 
ATOM   428  N N   . ALA A 1 67  ? 27.343 -28.956 2.430   1.000 46.787  0 71  ALA A N   1 ? 
ATOM   429  C CA  . ALA A 1 67  ? 27.773 -27.589 2.180   1.000 50.659  0 71  ALA A CA  1 ? 
ATOM   430  C C   . ALA A 1 67  ? 29.240 -27.549 1.785   1.000 49.235  0 71  ALA A C   1 ? 
ATOM   431  O O   . ALA A 1 67  ? 29.651 -26.686 0.998   1.000 50.846  0 71  ALA A O   1 ? 
ATOM   432  C CB  . ALA A 1 67  ? 27.514 -26.715 3.402   1.000 50.243  0 71  ALA A CB  1 ? 
ATOM   433  N N   . VAL A 1 68  ? 30.039 -28.483 2.300   1.000 43.387  0 72  VAL A N   1 ? 
ATOM   434  C CA  . VAL A 1 68  ? 31.444 -28.506 1.928   1.000 46.092  0 72  VAL A CA  1 ? 
ATOM   435  C C   . VAL A 1 68  ? 31.601 -29.012 0.502   1.000 46.632  0 72  VAL A C   1 ? 
ATOM   436  O O   . VAL A 1 68  ? 32.388 -28.466 -0.282  1.000 46.163  0 72  VAL A O   1 ? 
ATOM   437  C CB  . VAL A 1 68  ? 32.246 -29.349 2.931   1.000 49.682  0 72  VAL A CB  1 ? 
ATOM   438  C CG1 . VAL A 1 68  ? 33.662 -29.521 2.450   1.000 42.624  0 72  VAL A CG1 1 ? 
ATOM   439  C CG2 . VAL A 1 68  ? 32.231 -28.693 4.300   1.000 49.819  0 72  VAL A CG2 1 ? 
ATOM   440  N N   . LEU A 1 69  ? 30.845 -30.052 0.137   1.000 44.669  0 73  LEU A N   1 ? 
ATOM   441  C CA  . LEU A 1 69  ? 30.892 -30.545 -1.235  1.000 35.891  0 73  LEU A CA  1 ? 
ATOM   442  C C   . LEU A 1 69  ? 30.517 -29.443 -2.207  1.000 38.136  0 73  LEU A C   1 ? 
ATOM   443  O O   . LEU A 1 69  ? 31.186 -29.259 -3.227  1.000 40.434  0 73  LEU A O   1 ? 
ATOM   444  C CB  . LEU A 1 69  ? 29.964 -31.752 -1.406  1.000 38.952  0 73  LEU A CB  1 ? 
ATOM   445  C CG  . LEU A 1 69  ? 29.417 -32.013 -2.821  1.000 44.468  0 73  LEU A CG  1 ? 
ATOM   446  C CD1 . LEU A 1 69  ? 30.525 -32.363 -3.806  1.000 37.952  0 73  LEU A CD1 1 ? 
ATOM   447  C CD2 . LEU A 1 69  ? 28.359 -33.099 -2.829  1.000 43.229  0 73  LEU A CD2 1 ? 
ATOM   448  N N   . ILE A 1 70  ? 29.464 -28.683 -1.883  1.000 44.013  0 74  ILE A N   1 ? 
ATOM   449  C CA  . ILE A 1 70  ? 28.999 -27.593 -2.742  1.000 53.854  0 74  ILE A CA  1 ? 
ATOM   450  C C   . ILE A 1 70  ? 30.072 -26.518 -2.882  1.000 48.903  0 74  ILE A C   1 ? 
ATOM   451  O O   . ILE A 1 70  ? 30.401 -26.084 -3.991  1.000 50.111  0 74  ILE A O   1 ? 
ATOM   452  C CB  . ILE A 1 70  ? 27.692 -26.996 -2.187  1.000 53.751  0 74  ILE A CB  1 ? 
ATOM   453  C CG1 . ILE A 1 70  ? 26.535 -27.988 -2.328  1.000 47.006  0 74  ILE A CG1 1 ? 
ATOM   454  C CG2 . ILE A 1 70  ? 27.391 -25.633 -2.841  1.000 45.284  0 74  ILE A CG2 1 ? 
ATOM   455  C CD1 . ILE A 1 70  ? 25.298 -27.566 -1.544  1.000 44.726  0 74  ILE A CD1 1 ? 
ATOM   456  N N   . GLU A 1 71  ? 30.616 -26.057 -1.756  1.000 42.697  0 75  GLU A N   1 ? 
ATOM   457  C CA  . GLU A 1 71  ? 31.675 -25.059 -1.811  1.000 49.951  0 75  GLU A CA  1 ? 
ATOM   458  C C   . GLU A 1 71  ? 32.939 -25.586 -2.478  1.000 56.507  0 75  GLU A C   1 ? 
ATOM   459  O O   . GLU A 1 71  ? 33.763 -24.786 -2.933  1.000 66.087  0 75  GLU A O   1 ? 
ATOM   460  C CB  . GLU A 1 71  ? 31.993 -24.558 -0.406  1.000 50.585  0 75  GLU A CB  1 ? 
ATOM   461  C CG  . GLU A 1 71  ? 31.020 -23.501 0.076   1.000 57.346  0 75  GLU A CG  1 ? 
ATOM   462  C CD  . GLU A 1 71  ? 31.432 -22.881 1.392   1.000 61.686  0 75  GLU A CD  1 ? 
ATOM   463  O OE1 . GLU A 1 71  ? 31.372 -23.589 2.413   1.000 66.766  0 75  GLU A OE1 1 ? 
ATOM   464  O OE2 . GLU A 1 71  ? 31.806 -21.689 1.410   1.000 68.011  0 75  GLU A OE2 1 ? 
ATOM   465  N N   . THR A 1 72  ? 33.105 -26.907 -2.559  1.000 54.604  0 76  THR A N   1 ? 
ATOM   466  C CA  . THR A 1 72  ? 34.253 -27.476 -3.258  1.000 52.593  0 76  THR A CA  1 ? 
ATOM   467  C C   . THR A 1 72  ? 34.044 -27.474 -4.768  1.000 48.966  0 76  THR A C   1 ? 
ATOM   468  O O   . THR A 1 72  ? 34.957 -27.130 -5.532  1.000 42.666  0 76  THR A O   1 ? 
ATOM   469  C CB  . THR A 1 72  ? 34.516 -28.894 -2.759  1.000 46.411  0 76  THR A CB  1 ? 
ATOM   470  O OG1 . THR A 1 72  ? 34.848 -28.834 -1.374  1.000 41.455  0 76  THR A OG1 1 ? 
ATOM   471  C CG2 . THR A 1 72  ? 35.673 -29.544 -3.536  1.000 50.953  0 76  THR A CG2 1 ? 
ATOM   472  N N   . LEU A 1 73  ? 32.848 -27.874 -5.213  1.000 50.361  0 77  LEU A N   1 ? 
ATOM   473  C CA  . LEU A 1 73  ? 32.490 -27.715 -6.618  1.000 51.751  0 77  LEU A CA  1 ? 
ATOM   474  C C   . LEU A 1 73  ? 32.578 -26.259 -7.045  1.000 54.614  0 77  LEU A C   1 ? 
ATOM   475  O O   . LEU A 1 73  ? 32.967 -25.973 -8.180  1.000 56.191  0 77  LEU A O   1 ? 
ATOM   476  C CB  . LEU A 1 73  ? 31.078 -28.232 -6.880  1.000 53.635  0 77  LEU A CB  1 ? 
ATOM   477  C CG  . LEU A 1 73  ? 30.676 -29.671 -6.568  1.000 56.294  0 77  LEU A CG  1 ? 
ATOM   478  C CD1 . LEU A 1 73  ? 29.152 -29.781 -6.622  1.000 53.551  0 77  LEU A CD1 1 ? 
ATOM   479  C CD2 . LEU A 1 73  ? 31.339 -30.649 -7.535  1.000 58.320  0 77  LEU A CD2 1 ? 
ATOM   480  N N   . VAL A 1 74  ? 32.220 -25.326 -6.160  1.000 57.312  0 78  VAL A N   1 ? 
ATOM   481  C CA  . VAL A 1 74  ? 32.320 -23.914 -6.512  1.000 65.179  0 78  VAL A CA  1 ? 
ATOM   482  C C   . VAL A 1 74  ? 33.782 -23.504 -6.626  1.000 63.797  0 78  VAL A C   1 ? 
ATOM   483  O O   . VAL A 1 74  ? 34.200 -22.900 -7.619  1.000 62.815  0 78  VAL A O   1 ? 
ATOM   484  C CB  . VAL A 1 74  ? 31.555 -23.039 -5.498  1.000 60.431  0 78  VAL A CB  1 ? 
ATOM   485  C CG1 . VAL A 1 74  ? 32.033 -21.579 -5.570  1.000 48.164  0 78  VAL A CG1 1 ? 
ATOM   486  C CG2 . VAL A 1 74  ? 30.035 -23.127 -5.744  1.000 52.233  0 78  VAL A CG2 1 ? 
ATOM   487  N N   . ALA A 1 75  ? 34.587 -23.846 -5.622  1.000 69.477  0 79  ALA A N   1 ? 
ATOM   488  C CA  . ALA A 1 75  ? 36.008 -23.527 -5.670  1.000 73.875  0 79  ALA A CA  1 ? 
ATOM   489  C C   . ALA A 1 75  ? 36.699 -24.110 -6.894  1.000 72.411  0 79  ALA A C   1 ? 
ATOM   490  O O   . ALA A 1 75  ? 37.811 -23.674 -7.214  1.000 72.440  0 79  ALA A O   1 ? 
ATOM   491  C CB  . ALA A 1 75  ? 36.695 -24.022 -4.394  1.000 70.077  0 79  ALA A CB  1 ? 
ATOM   492  N N   . LEU A 1 76  ? 36.077 -25.081 -7.575  1.000 66.629  0 80  LEU A N   1 ? 
ATOM   493  C CA  . LEU A 1 76  ? 36.598 -25.650 -8.814  1.000 63.571  0 80  LEU A CA  1 ? 
ATOM   494  C C   . LEU A 1 76  ? 35.955 -25.028 -10.059 1.000 66.005  0 80  LEU A C   1 ? 
ATOM   495  O O   . LEU A 1 76  ? 36.156 -25.530 -11.175 1.000 53.130  0 80  LEU A O   1 ? 
ATOM   496  C CB  . LEU A 1 76  ? 36.416 -27.175 -8.820  1.000 51.282  0 80  LEU A CB  1 ? 
ATOM   497  C CG  . LEU A 1 76  ? 37.128 -27.981 -7.718  1.000 50.361  0 80  LEU A CG  1 ? 
ATOM   498  C CD1 . LEU A 1 76  ? 37.328 -29.428 -8.134  1.000 50.661  0 80  LEU A CD1 1 ? 
ATOM   499  C CD2 . LEU A 1 76  ? 38.448 -27.359 -7.313  1.000 48.419  0 80  LEU A CD2 1 ? 
ATOM   500  N N   . GLY A 1 77  ? 35.180 -23.953 -9.883  1.000 71.359  0 81  GLY A N   1 ? 
ATOM   501  C CA  . GLY A 1 77  ? 34.672 -23.145 -10.973 1.000 71.761  0 81  GLY A CA  1 ? 
ATOM   502  C C   . GLY A 1 77  ? 33.207 -23.331 -11.307 1.000 74.867  0 81  GLY A C   1 ? 
ATOM   503  O O   . GLY A 1 77  ? 32.701 -22.610 -12.177 1.000 79.649  0 81  GLY A O   1 ? 
ATOM   504  N N   . ALA A 1 78  ? 32.495 -24.241 -10.642 1.000 70.343  0 82  ALA A N   1 ? 
ATOM   505  C CA  . ALA A 1 78  ? 31.165 -24.619 -11.108 1.000 67.329  0 82  ALA A CA  1 ? 
ATOM   506  C C   . ALA A 1 78  ? 30.080 -23.649 -10.628 1.000 64.352  0 82  ALA A C   1 ? 
ATOM   507  O O   . ALA A 1 78  ? 30.233 -22.915 -9.647  1.000 60.544  0 82  ALA A O   1 ? 
ATOM   508  C CB  . ALA A 1 78  ? 30.816 -26.046 -10.669 1.000 59.555  0 82  ALA A CB  1 ? 
ATOM   509  N N   . GLU A 1 79  ? 28.977 -23.647 -11.369 1.000 61.489  0 83  GLU A N   1 ? 
ATOM   510  C CA  . GLU A 1 79  ? 27.734 -23.003 -10.983 1.000 64.087  0 83  GLU A CA  1 ? 
ATOM   511  C C   . GLU A 1 79  ? 26.778 -24.103 -10.544 1.000 64.745  0 83  GLU A C   1 ? 
ATOM   512  O O   . GLU A 1 79  ? 26.710 -25.157 -11.187 1.000 63.687  0 83  GLU A O   1 ? 
ATOM   513  C CB  . GLU A 1 79  ? 27.143 -22.232 -12.168 1.000 77.238  0 83  GLU A CB  1 ? 
ATOM   514  C CG  . GLU A 1 79  ? 26.650 -20.817 -11.875 1.000 82.523  0 83  GLU A CG  1 ? 
ATOM   515  C CD  . GLU A 1 79  ? 26.737 -19.914 -13.106 1.000 78.904  0 83  GLU A CD  1 ? 
ATOM   516  O OE1 . GLU A 1 79  ? 25.690 -19.532 -13.671 1.000 79.725  0 83  GLU A OE1 1 ? 
ATOM   517  O OE2 . GLU A 1 79  ? 27.867 -19.588 -13.516 1.000 72.993  0 83  GLU A OE2 1 ? 
ATOM   518  N N   . VAL A 1 80  ? 26.054 -23.879 -9.442  1.000 62.126  0 84  VAL A N   1 ? 
ATOM   519  C CA  . VAL A 1 80  ? 25.154 -24.897 -8.905  1.000 64.252  0 84  VAL A CA  1 ? 
ATOM   520  C C   . VAL A 1 80  ? 23.846 -24.277 -8.420  1.000 55.546  0 84  VAL A C   1 ? 
ATOM   521  O O   . VAL A 1 80  ? 23.768 -23.094 -8.085  1.000 53.420  0 84  VAL A O   1 ? 
ATOM   522  C CB  . VAL A 1 80  ? 25.801 -25.725 -7.752  1.000 70.506  0 84  VAL A CB  1 ? 
ATOM   523  C CG1 . VAL A 1 80  ? 27.098 -26.409 -8.211  1.000 68.811  0 84  VAL A CG1 1 ? 
ATOM   524  C CG2 . VAL A 1 80  ? 26.033 -24.866 -6.504  1.000 65.479  0 84  VAL A CG2 1 ? 
ATOM   525  N N   . ARG A 1 81  ? 22.803 -25.105 -8.417  1.000 50.901  0 85  ARG A N   1 ? 
ATOM   526  C CA  . ARG A 1 81  ? 21.581 -24.883 -7.652  1.000 59.078  0 85  ARG A CA  1 ? 
ATOM   527  C C   . ARG A 1 81  ? 21.272 -26.172 -6.901  1.000 60.660  0 85  ARG A C   1 ? 
ATOM   528  O O   . ARG A 1 81  ? 21.341 -27.262 -7.482  1.000 49.148  0 85  ARG A O   1 ? 
ATOM   529  C CB  . ARG A 1 81  ? 20.409 -24.490 -8.556  1.000 57.862  0 85  ARG A CB  1 ? 
ATOM   530  C CG  . ARG A 1 81  ? 20.765 -23.454 -9.602  1.000 55.175  0 85  ARG A CG  1 ? 
ATOM   531  C CD  . ARG A 1 81  ? 19.652 -23.278 -10.633 1.000 61.394  0 85  ARG A CD  1 ? 
ATOM   532  N NE  . ARG A 1 81  ? 18.475 -22.600 -10.103 1.000 62.457  0 85  ARG A NE  1 ? 
ATOM   533  C CZ  . ARG A 1 81  ? 18.436 -21.312 -9.783  1.000 64.192  0 85  ARG A CZ  1 ? 
ATOM   534  N NH1 . ARG A 1 81  ? 19.521 -20.551 -9.938  1.000 63.389  0 85  ARG A NH1 1 ? 
ATOM   535  N NH2 . ARG A 1 81  ? 17.315 -20.788 -9.300  1.000 60.886  0 85  ARG A NH2 1 ? 
ATOM   536  N N   . TRP A 1 82  ? 20.950 -26.062 -5.616  1.000 58.596  0 86  TRP A N   1 ? 
ATOM   537  C CA  . TRP A 1 82  ? 20.806 -27.262 -4.802  1.000 58.094  0 86  TRP A CA  1 ? 
ATOM   538  C C   . TRP A 1 82  ? 19.380 -27.434 -4.309  1.000 53.291  0 86  TRP A C   1 ? 
ATOM   539  O O   . TRP A 1 82  ? 18.552 -26.526 -4.396  1.000 49.790  0 86  TRP A O   1 ? 
ATOM   540  C CB  . TRP A 1 82  ? 21.754 -27.255 -3.599  1.000 61.518  0 86  TRP A CB  1 ? 
ATOM   541  C CG  . TRP A 1 82  ? 22.329 -28.610 -3.351  1.000 59.820  0 86  TRP A CG  1 ? 
ATOM   542  C CD1 . TRP A 1 82  ? 21.887 -29.553 -2.457  1.000 57.902  0 86  TRP A CD1 1 ? 
ATOM   543  C CD2 . TRP A 1 82  ? 23.433 -29.189 -4.034  1.000 52.498  0 86  TRP A CD2 1 ? 
ATOM   544  N NE1 . TRP A 1 82  ? 22.665 -30.683 -2.538  1.000 47.156  0 86  TRP A NE1 1 ? 
ATOM   545  C CE2 . TRP A 1 82  ? 23.622 -30.486 -3.501  1.000 57.038  0 86  TRP A CE2 1 ? 
ATOM   546  C CE3 . TRP A 1 82  ? 24.291 -28.735 -5.038  1.000 46.945  0 86  TRP A CE3 1 ? 
ATOM   547  C CZ2 . TRP A 1 82  ? 24.641 -31.330 -3.939  1.000 62.871  0 86  TRP A CZ2 1 ? 
ATOM   548  C CZ3 . TRP A 1 82  ? 25.297 -29.566 -5.472  1.000 55.951  0 86  TRP A CZ3 1 ? 
ATOM   549  C CH2 . TRP A 1 82  ? 25.466 -30.856 -4.925  1.000 61.649  0 86  TRP A CH2 1 ? 
ATOM   550  N N   . SER A 1 83  ? 19.120 -28.636 -3.791  1.000 49.351  0 87  SER A N   1 ? 
ATOM   551  C CA  . SER A 1 83  ? 17.862 -29.015 -3.161  1.000 53.991  0 87  SER A CA  1 ? 
ATOM   552  C C   . SER A 1 83  ? 18.080 -30.336 -2.443  1.000 53.293  0 87  SER A C   1 ? 
ATOM   553  O O   . SER A 1 83  ? 18.811 -31.192 -2.942  1.000 50.306  0 87  SER A O   1 ? 
ATOM   554  C CB  . SER A 1 83  ? 16.724 -29.156 -4.187  1.000 55.796  0 87  SER A CB  1 ? 
ATOM   555  O OG  . SER A 1 83  ? 16.811 -30.389 -4.885  1.000 50.482  0 87  SER A OG  1 ? 
ATOM   556  N N   . SER A 1 84  ? 17.449 -30.498 -1.284  1.000 56.820  0 88  SER A N   1 ? 
ATOM   557  C CA  . SER A 1 84  ? 17.508 -31.784 -0.610  1.000 63.881  0 88  SER A CA  1 ? 
ATOM   558  C C   . SER A 1 84  ? 16.745 -32.844 -1.411  1.000 72.340  0 88  SER A C   1 ? 
ATOM   559  O O   . SER A 1 84  ? 15.893 -32.537 -2.250  1.000 80.336  0 88  SER A O   1 ? 
ATOM   560  C CB  . SER A 1 84  ? 16.940 -31.680 0.803   1.000 57.854  0 88  SER A CB  1 ? 
ATOM   561  O OG  . SER A 1 84  ? 17.445 -32.723 1.623   1.000 55.149  0 88  SER A OG  1 ? 
ATOM   562  N N   . CYS A 1 85  ? 17.078 -34.109 -1.160  1.000 66.526  0 89  CYS A N   1 ? 
ATOM   563  C CA  . CYS A 1 85  ? 16.345 -35.231 -1.734  1.000 68.400  0 89  CYS A CA  1 ? 
ATOM   564  C C   . CYS A 1 85  ? 15.434 -35.906 -0.714  1.000 66.537  0 89  CYS A C   1 ? 
ATOM   565  O O   . CYS A 1 85  ? 14.895 -36.981 -0.992  1.000 65.929  0 89  CYS A O   1 ? 
ATOM   566  C CB  . CYS A 1 85  ? 17.313 -36.256 -2.345  1.000 69.053  0 89  CYS A CB  1 ? 
ATOM   567  S SG  . CYS A 1 85  ? 18.479 -37.101 -1.193  1.000 57.467  0 89  CYS A SG  1 ? 
ATOM   568  N N   . ASN A 1 86  ? 15.243 -35.295 0.451   1.000 60.115  0 90  ASN A N   1 ? 
ATOM   569  C CA  . ASN A 1 86  ? 14.344 -35.814 1.465   1.000 56.523  0 90  ASN A CA  1 ? 
ATOM   570  C C   . ASN A 1 86  ? 13.714 -34.633 2.189   1.000 58.983  0 90  ASN A C   1 ? 
ATOM   571  O O   . ASN A 1 86  ? 14.381 -33.627 2.453   1.000 63.118  0 90  ASN A O   1 ? 
ATOM   572  C CB  . ASN A 1 86  ? 15.087 -36.733 2.444   1.000 57.115  0 90  ASN A CB  1 ? 
ATOM   573  C CG  . ASN A 1 86  ? 14.156 -37.655 3.216   1.000 56.096  0 90  ASN A CG  1 ? 
ATOM   574  O OD1 . ASN A 1 86  ? 13.585 -37.267 4.237   1.000 51.053  0 90  ASN A OD1 1 ? 
ATOM   575  N ND2 . ASN A 1 86  ? 14.011 -38.888 2.735   1.000 58.318  0 90  ASN A ND2 1 ? 
ATOM   576  N N   . ILE A 1 87  ? 12.424 -34.763 2.511   1.000 55.062  0 91  ILE A N   1 ? 
ATOM   577  C CA  . ILE A 1 87  ? 11.700 -33.655 3.118   1.000 50.674  0 91  ILE A CA  1 ? 
ATOM   578  C C   . ILE A 1 87  ? 12.137 -33.388 4.554   1.000 47.193  0 91  ILE A C   1 ? 
ATOM   579  O O   . ILE A 1 87  ? 11.789 -32.346 5.118   1.000 55.141  0 91  ILE A O   1 ? 
ATOM   580  C CB  . ILE A 1 87  ? 10.186 -33.914 3.084   1.000 53.778  0 91  ILE A CB  1 ? 
ATOM   581  C CG1 . ILE A 1 87  ? 9.843  -35.127 3.959   1.000 46.737  0 91  ILE A CG1 1 ? 
ATOM   582  C CG2 . ILE A 1 87  ? 9.700  -34.091 1.636   1.000 47.966  0 91  ILE A CG2 1 ? 
ATOM   583  C CD1 . ILE A 1 87  ? 8.358  -35.251 4.258   1.000 47.335  0 91  ILE A CD1 1 ? 
ATOM   584  N N   . PHE A 1 88  ? 12.877 -34.295 5.178   1.000 43.608  0 92  PHE A N   1 ? 
ATOM   585  C CA  . PHE A 1 88  ? 13.326 -34.081 6.545   1.000 49.624  0 92  PHE A CA  1 ? 
ATOM   586  C C   . PHE A 1 88  ? 14.840 -33.992 6.679   1.000 49.890  0 92  PHE A C   1 ? 
ATOM   587  O O   . PHE A 1 88  ? 15.330 -33.809 7.798   1.000 44.900  0 92  PHE A O   1 ? 
ATOM   588  C CB  . PHE A 1 88  ? 12.800 -35.190 7.477   1.000 50.801  0 92  PHE A CB  1 ? 
ATOM   589  C CG  . PHE A 1 88  ? 11.293 -35.235 7.595   1.000 48.335  0 92  PHE A CG  1 ? 
ATOM   590  C CD1 . PHE A 1 88  ? 10.566 -34.085 7.881   1.000 48.558  0 92  PHE A CD1 1 ? 
ATOM   591  C CD2 . PHE A 1 88  ? 10.607 -36.435 7.425   1.000 45.279  0 92  PHE A CD2 1 ? 
ATOM   592  C CE1 . PHE A 1 88  ? 9.177  -34.126 7.981   1.000 53.551  0 92  PHE A CE1 1 ? 
ATOM   593  C CE2 . PHE A 1 88  ? 9.213  -36.486 7.522   1.000 52.406  0 92  PHE A CE2 1 ? 
ATOM   594  C CZ  . PHE A 1 88  ? 8.499  -35.331 7.802   1.000 54.228  0 92  PHE A CZ  1 ? 
ATOM   595  N N   . SER A 1 89  ? 15.593 -34.082 5.577   1.000 62.015  0 93  SER A N   1 ? 
ATOM   596  C CA  . SER A 1 89  ? 17.040 -34.268 5.645   1.000 61.318  0 93  SER A CA  1 ? 
ATOM   597  C C   . SER A 1 89  ? 17.832 -32.967 5.647   1.000 58.341  0 93  SER A C   1 ? 
ATOM   598  O O   . SER A 1 89  ? 18.979 -32.965 6.113   1.000 56.686  0 93  SER A O   1 ? 
ATOM   599  C CB  . SER A 1 89  ? 17.519 -35.140 4.474   1.000 60.607  0 93  SER A CB  1 ? 
ATOM   600  O OG  . SER A 1 89  ? 17.248 -34.523 3.224   1.000 58.560  0 93  SER A OG  1 ? 
ATOM   601  N N   . THR A 1 90  ? 17.275 -31.875 5.126   1.000 51.988  0 94  THR A N   1 ? 
ATOM   602  C CA  . THR A 1 90  ? 17.992 -30.611 5.162   1.000 57.662  0 94  THR A CA  1 ? 
ATOM   603  C C   . THR A 1 90  ? 18.356 -30.256 6.598   1.000 63.655  0 94  THR A C   1 ? 
ATOM   604  O O   . THR A 1 90  ? 17.520 -30.348 7.503   1.000 40.673  0 94  THR A O   1 ? 
ATOM   605  C CB  . THR A 1 90  ? 17.149 -29.488 4.561   1.000 59.544  0 94  THR A CB  1 ? 
ATOM   606  O OG1 . THR A 1 90  ? 16.972 -29.706 3.158   1.000 60.265  0 94  THR A OG1 1 ? 
ATOM   607  C CG2 . THR A 1 90  ? 17.821 -28.142 4.797   1.000 43.450  0 94  THR A CG2 1 ? 
ATOM   608  N N   . GLN A 1 91  ? 19.619 -29.889 6.809   1.000 62.121  0 95  GLN A N   1 ? 
ATOM   609  C CA  . GLN A 1 91  ? 20.015 -29.103 7.972   1.000 56.244  0 95  GLN A CA  1 ? 
ATOM   610  C C   . GLN A 1 91  ? 19.870 -27.631 7.616   1.000 58.270  0 95  GLN A C   1 ? 
ATOM   611  O O   . GLN A 1 91  ? 20.464 -27.160 6.641   1.000 63.005  0 95  GLN A O   1 ? 
ATOM   612  C CB  . GLN A 1 91  ? 21.447 -29.409 8.378   1.000 50.780  0 95  GLN A CB  1 ? 
ATOM   613  C CG  . GLN A 1 91  ? 21.663 -30.831 8.748   1.000 48.624  0 95  GLN A CG  1 ? 
ATOM   614  C CD  . GLN A 1 91  ? 23.052 -31.052 9.255   1.000 59.407  0 95  GLN A CD  1 ? 
ATOM   615  O OE1 . GLN A 1 91  ? 23.990 -31.206 8.475   1.000 64.281  0 95  GLN A OE1 1 ? 
ATOM   616  N NE2 . GLN A 1 91  ? 23.207 -31.053 10.573  1.000 60.357  0 95  GLN A NE2 1 ? 
ATOM   617  N N   . ASP A 1 92  ? 19.088 -26.904 8.404   1.000 58.194  0 96  ASP A N   1 ? 
ATOM   618  C CA  . ASP A 1 92  ? 18.692 -25.573 7.973   1.000 54.441  0 96  ASP A CA  1 ? 
ATOM   619  C C   . ASP A 1 92  ? 19.854 -24.589 8.033   1.000 58.554  0 96  ASP A C   1 ? 
ATOM   620  O O   . ASP A 1 92  ? 20.038 -23.781 7.114   1.000 59.320  0 96  ASP A O   1 ? 
ATOM   621  C CB  . ASP A 1 92  ? 17.514 -25.099 8.811   1.000 59.931  0 96  ASP A CB  1 ? 
ATOM   622  C CG  . ASP A 1 92  ? 16.182 -25.530 8.225   1.000 64.026  0 96  ASP A CG  1 ? 
ATOM   623  O OD1 . ASP A 1 92  ? 15.981 -25.311 6.998   1.000 68.082  0 96  ASP A OD1 1 ? 
ATOM   624  O OD2 . ASP A 1 92  ? 15.350 -26.082 8.991   1.000 52.083  0 96  ASP A OD2 1 ? 
ATOM   625  N N   . HIS A 1 93  ? 20.651 -24.634 9.103   1.000 57.649  0 97  HIS A N   1 ? 
ATOM   626  C CA  . HIS A 1 93  ? 21.775 -23.708 9.193   1.000 53.435  0 97  HIS A CA  1 ? 
ATOM   627  C C   . HIS A 1 93  ? 22.794 -23.970 8.099   1.000 51.698  0 97  HIS A C   1 ? 
ATOM   628  O O   . HIS A 1 93  ? 23.472 -23.039 7.646   1.000 50.580  0 97  HIS A O   1 ? 
ATOM   629  C CB  . HIS A 1 93  ? 22.441 -23.808 10.560  1.000 51.025  0 97  HIS A CB  1 ? 
ATOM   630  C CG  . HIS A 1 93  ? 22.777 -25.208 10.959  1.000 53.341  0 97  HIS A CG  1 ? 
ATOM   631  N ND1 . HIS A 1 93  ? 21.813 -26.163 11.203  1.000 54.056  0 97  HIS A ND1 1 ? 
ATOM   632  C CD2 . HIS A 1 93  ? 23.970 -25.816 11.159  1.000 52.312  0 97  HIS A CD2 1 ? 
ATOM   633  C CE1 . HIS A 1 93  ? 22.397 -27.299 11.536  1.000 51.164  0 97  HIS A CE1 1 ? 
ATOM   634  N NE2 . HIS A 1 93  ? 23.706 -27.116 11.516  1.000 51.077  0 97  HIS A NE2 1 ? 
ATOM   635  N N   . ALA A 1 94  ? 22.930 -25.227 7.678   1.000 49.832  0 98  ALA A N   1 ? 
ATOM   636  C CA  . ALA A 1 94  ? 23.784 -25.525 6.537   1.000 50.219  0 98  ALA A CA  1 ? 
ATOM   637  C C   . ALA A 1 94  ? 23.227 -24.871 5.285   1.000 53.614  0 98  ALA A C   1 ? 
ATOM   638  O O   . ALA A 1 94  ? 23.926 -24.118 4.595   1.000 52.859  0 98  ALA A O   1 ? 
ATOM   639  C CB  . ALA A 1 94  ? 23.910 -27.036 6.357   1.000 38.563  0 98  ALA A CB  1 ? 
ATOM   640  N N   . ALA A 1 95  ? 21.946 -25.122 5.002   1.000 51.919  0 99  ALA A N   1 ? 
ATOM   641  C CA  . ALA A 1 95  ? 21.273 -24.452 3.895   1.000 54.499  0 99  ALA A CA  1 ? 
ATOM   642  C C   . ALA A 1 95  ? 21.384 -22.933 4.009   1.000 55.875  0 99  ALA A C   1 ? 
ATOM   643  O O   . ALA A 1 95  ? 21.540 -22.234 3.001   1.000 55.788  0 99  ALA A O   1 ? 
ATOM   644  C CB  . ALA A 1 95  ? 19.803 -24.887 3.845   1.000 49.848  0 99  ALA A CB  1 ? 
ATOM   645  N N   . SER A 1 96  ? 21.305 -22.404 5.228   1.000 57.815  0 100 SER A N   1 ? 
ATOM   646  C CA  . SER A 1 96  ? 21.363 -20.959 5.394   1.000 60.613  0 100 SER A CA  1 ? 
ATOM   647  C C   . SER A 1 96  ? 22.743 -20.418 5.046   1.000 54.757  0 100 SER A C   1 ? 
ATOM   648  O O   . SER A 1 96  ? 22.859 -19.384 4.380   1.000 52.975  0 100 SER A O   1 ? 
ATOM   649  C CB  . SER A 1 96  ? 20.962 -20.587 6.822   1.000 62.902  0 100 SER A CB  1 ? 
ATOM   650  O OG  . SER A 1 96  ? 19.553 -20.657 6.976   1.000 59.912  0 100 SER A OG  1 ? 
ATOM   651  N N   . ALA A 1 97  ? 23.798 -21.111 5.474   1.000 52.938  0 101 ALA A N   1 ? 
ATOM   652  C CA  . ALA A 1 97  ? 25.154 -20.657 5.187   1.000 54.593  0 101 ALA A CA  1 ? 
ATOM   653  C C   . ALA A 1 97  ? 25.471 -20.724 3.697   1.000 60.973  0 101 ALA A C   1 ? 
ATOM   654  O O   . ALA A 1 97  ? 26.254 -19.907 3.192   1.000 63.921  0 101 ALA A O   1 ? 
ATOM   655  C CB  . ALA A 1 97  ? 26.161 -21.488 5.985   1.000 42.055  0 101 ALA A CB  1 ? 
ATOM   656  N N   . ILE A 1 98  ? 24.887 -21.694 2.988   1.000 59.981  0 102 ILE A N   1 ? 
ATOM   657  C CA  . ILE A 1 98  ? 25.071 -21.784 1.542   1.000 57.170  0 102 ILE A CA  1 ? 
ATOM   658  C C   . ILE A 1 98  ? 24.400 -20.604 0.847   1.000 62.665  0 102 ILE A C   1 ? 
ATOM   659  O O   . ILE A 1 98  ? 24.987 -19.970 -0.039  1.000 65.453  0 102 ILE A O   1 ? 
ATOM   660  C CB  . ILE A 1 98  ? 24.524 -23.125 1.019   1.000 56.041  0 102 ILE A CB  1 ? 
ATOM   661  C CG1 . ILE A 1 98  ? 25.435 -24.290 1.418   1.000 57.633  0 102 ILE A CG1 1 ? 
ATOM   662  C CG2 . ILE A 1 98  ? 24.351 -23.081 -0.486  1.000 54.401  0 102 ILE A CG2 1 ? 
ATOM   663  C CD1 . ILE A 1 98  ? 26.825 -24.229 0.807   1.000 58.254  0 102 ILE A CD1 1 ? 
ATOM   664  N N   . ALA A 1 99  ? 23.158 -20.293 1.240   1.000 59.815  0 103 ALA A N   1 ? 
ATOM   665  C CA  . ALA A 1 99  ? 22.423 -19.201 0.603   1.000 60.594  0 103 ALA A CA  1 ? 
ATOM   666  C C   . ALA A 1 99  ? 23.085 -17.855 0.871   1.000 60.086  0 103 ALA A C   1 ? 
ATOM   667  O O   . ALA A 1 99  ? 23.136 -16.987 -0.012  1.000 56.609  0 103 ALA A O   1 ? 
ATOM   668  C CB  . ALA A 1 99  ? 20.973 -19.182 1.091   1.000 51.585  0 103 ALA A CB  1 ? 
ATOM   669  N N   . ALA A 1 100 ? 23.593 -17.664 2.091   1.000 59.423  0 104 ALA A N   1 ? 
ATOM   670  C CA  . ALA A 1 100 ? 24.306 -16.438 2.425   1.000 56.554  0 104 ALA A CA  1 ? 
ATOM   671  C C   . ALA A 1 100 ? 25.517 -16.231 1.532   1.000 63.600  0 104 ALA A C   1 ? 
ATOM   672  O O   . ALA A 1 100 ? 25.915 -15.086 1.286   1.000 65.829  0 104 ALA A O   1 ? 
ATOM   673  C CB  . ALA A 1 100 ? 24.737 -16.466 3.887   1.000 52.075  0 104 ALA A CB  1 ? 
ATOM   674  N N   . LYS A 1 101 ? 26.114 -17.317 1.039   1.000 62.831  0 105 LYS A N   1 ? 
ATOM   675  C CA  . LYS A 1 101 ? 27.236 -17.201 0.119   1.000 65.324  0 105 LYS A CA  1 ? 
ATOM   676  C C   . LYS A 1 101 ? 26.794 -16.956 -1.321  1.000 68.974  0 105 LYS A C   1 ? 
ATOM   677  O O   . LYS A 1 101 ? 27.611 -17.103 -2.233  1.000 72.651  0 105 LYS A O   1 ? 
ATOM   678  C CB  . LYS A 1 101 ? 28.116 -18.450 0.200   1.000 61.513  0 105 LYS A CB  1 ? 
ATOM   679  C CG  . LYS A 1 101 ? 29.257 -18.343 1.207   1.000 64.853  0 105 LYS A CG  1 ? 
ATOM   680  C CD  . LYS A 1 101 ? 30.512 -17.814 0.545   1.000 71.027  0 105 LYS A CD  1 ? 
ATOM   681  C CE  . LYS A 1 101 ? 31.655 -17.660 1.534   1.000 76.941  0 105 LYS A CE  1 ? 
ATOM   682  N NZ  . LYS A 1 101 ? 32.955 -17.428 0.838   1.000 77.196  0 105 LYS A NZ  1 ? 
ATOM   683  N N   . GLY A 1 102 ? 25.535 -16.574 -1.545  1.000 67.937  0 106 GLY A N   1 ? 
ATOM   684  C CA  . GLY A 1 102 ? 25.059 -16.305 -2.888  1.000 65.782  0 106 GLY A CA  1 ? 
ATOM   685  C C   . GLY A 1 102 ? 24.816 -17.532 -3.736  1.000 63.208  0 106 GLY A C   1 ? 
ATOM   686  O O   . GLY A 1 102 ? 24.857 -17.449 -4.969  1.000 60.944  0 106 GLY A O   1 ? 
ATOM   687  N N   . ILE A 1 103 ? 24.567 -18.675 -3.121  1.000 66.142  0 107 ILE A N   1 ? 
ATOM   688  C CA  . ILE A 1 103 ? 24.346 -19.922 -3.846  1.000 71.485  0 107 ILE A CA  1 ? 
ATOM   689  C C   . ILE A 1 103 ? 22.860 -20.247 -3.800  1.000 69.943  0 107 ILE A C   1 ? 
ATOM   690  O O   . ILE A 1 103 ? 22.266 -20.238 -2.712  1.000 64.834  0 107 ILE A O   1 ? 
ATOM   691  C CB  . ILE A 1 103 ? 25.189 -21.069 -3.263  1.000 68.874  0 107 ILE A CB  1 ? 
ATOM   692  C CG1 . ILE A 1 103 ? 26.656 -20.632 -3.176  1.000 61.576  0 107 ILE A CG1 1 ? 
ATOM   693  C CG2 . ILE A 1 103 ? 25.043 -22.330 -4.115  1.000 69.966  0 107 ILE A CG2 1 ? 
ATOM   694  C CD1 . ILE A 1 103 ? 27.641 -21.773 -3.086  1.000 57.694  0 107 ILE A CD1 1 ? 
ATOM   695  N N   . PRO A 1 104 ? 22.220 -20.511 -4.940  1.000 70.677  0 108 PRO A N   1 ? 
ATOM   696  C CA  . PRO A 1 104 ? 20.781 -20.802 -4.921  1.000 75.283  0 108 PRO A CA  1 ? 
ATOM   697  C C   . PRO A 1 104 ? 20.534 -22.178 -4.316  1.000 70.627  0 108 PRO A C   1 ? 
ATOM   698  O O   . PRO A 1 104 ? 21.098 -23.182 -4.766  1.000 68.787  0 108 PRO A O   1 ? 
ATOM   699  C CB  . PRO A 1 104 ? 20.375 -20.727 -6.403  1.000 70.787  0 108 PRO A CB  1 ? 
ATOM   700  C CG  . PRO A 1 104 ? 21.625 -20.910 -7.170  1.000 72.853  0 108 PRO A CG  1 ? 
ATOM   701  C CD  . PRO A 1 104 ? 22.781 -20.491 -6.303  1.000 71.698  0 108 PRO A CD  1 ? 
ATOM   702  N N   . VAL A 1 105 ? 19.706 -22.211 -3.270  1.000 62.918  0 109 VAL A N   1 ? 
ATOM   703  C CA  . VAL A 1 105 ? 19.378 -23.447 -2.564  1.000 66.371  0 109 VAL A CA  1 ? 
ATOM   704  C C   . VAL A 1 105 ? 17.921 -23.387 -2.113  1.000 61.676  0 109 VAL A C   1 ? 
ATOM   705  O O   . VAL A 1 105 ? 17.450 -22.354 -1.629  1.000 67.850  0 109 VAL A O   1 ? 
ATOM   706  C CB  . VAL A 1 105 ? 20.338 -23.709 -1.368  1.000 65.747  0 109 VAL A CB  1 ? 
ATOM   707  C CG1 . VAL A 1 105 ? 20.433 -22.495 -0.436  1.000 63.363  0 109 VAL A CG1 1 ? 
ATOM   708  C CG2 . VAL A 1 105 ? 19.925 -24.970 -0.587  1.000 47.543  0 109 VAL A CG2 1 ? 
ATOM   709  N N   . PHE A 1 106 ? 17.217 -24.508 -2.272  1.000 60.060  0 110 PHE A N   1 ? 
ATOM   710  C CA  . PHE A 1 106 ? 15.796 -24.658 -1.954  1.000 61.823  0 110 PHE A CA  1 ? 
ATOM   711  C C   . PHE A 1 106 ? 15.639 -25.921 -1.108  1.000 59.594  0 110 PHE A C   1 ? 
ATOM   712  O O   . PHE A 1 106 ? 15.548 -27.034 -1.640  1.000 50.182  0 110 PHE A O   1 ? 
ATOM   713  C CB  . PHE A 1 106 ? 14.967 -24.711 -3.235  1.000 65.861  0 110 PHE A CB  1 ? 
ATOM   714  C CG  . PHE A 1 106 ? 15.428 -23.730 -4.261  1.000 70.361  0 110 PHE A CG  1 ? 
ATOM   715  C CD1 . PHE A 1 106 ? 16.469 -24.043 -5.122  1.000 74.996  0 110 PHE A CD1 1 ? 
ATOM   716  C CD2 . PHE A 1 106 ? 14.870 -22.466 -4.324  1.000 69.800  0 110 PHE A CD2 1 ? 
ATOM   717  C CE1 . PHE A 1 106 ? 16.921 -23.121 -6.051  1.000 76.583  0 110 PHE A CE1 1 ? 
ATOM   718  C CE2 . PHE A 1 106 ? 15.317 -21.543 -5.247  1.000 72.988  0 110 PHE A CE2 1 ? 
ATOM   719  C CZ  . PHE A 1 106 ? 16.343 -21.871 -6.114  1.000 74.398  0 110 PHE A CZ  1 ? 
ATOM   720  N N   . ALA A 1 107 ? 15.605 -25.734 0.211   1.000 58.378  0 111 ALA A N   1 ? 
ATOM   721  C CA  . ALA A 1 107 ? 15.685 -26.832 1.159   1.000 55.699  0 111 ALA A CA  1 ? 
ATOM   722  C C   . ALA A 1 107 ? 15.370 -26.299 2.542   1.000 53.712  0 111 ALA A C   1 ? 
ATOM   723  O O   . ALA A 1 107 ? 15.740 -25.170 2.877   1.000 49.190  0 111 ALA A O   1 ? 
ATOM   724  C CB  . ALA A 1 107 ? 17.080 -27.477 1.146   1.000 51.427  0 111 ALA A CB  1 ? 
ATOM   725  N N   . TRP A 1 108 ? 14.682 -27.117 3.329   1.000 52.009  0 112 TRP A N   1 ? 
ATOM   726  C CA  . TRP A 1 108 ? 14.418 -26.846 4.732   1.000 53.912  0 112 TRP A CA  1 ? 
ATOM   727  C C   . TRP A 1 108 ? 13.851 -28.110 5.348   1.000 53.925  0 112 TRP A C   1 ? 
ATOM   728  O O   . TRP A 1 108 ? 13.139 -28.865 4.681   1.000 52.264  0 112 TRP A O   1 ? 
ATOM   729  C CB  . TRP A 1 108 ? 13.438 -25.683 4.906   1.000 62.581  0 112 TRP A CB  1 ? 
ATOM   730  C CG  . TRP A 1 108 ? 12.128 -25.912 4.225   1.000 67.819  0 112 TRP A CG  1 ? 
ATOM   731  C CD1 . TRP A 1 108 ? 11.059 -26.612 4.714   1.000 64.618  0 112 TRP A CD1 1 ? 
ATOM   732  C CD2 . TRP A 1 108 ? 11.737 -25.437 2.927   1.000 71.780  0 112 TRP A CD2 1 ? 
ATOM   733  N NE1 . TRP A 1 108 ? 10.029 -26.597 3.801   1.000 68.627  0 112 TRP A NE1 1 ? 
ATOM   734  C CE2 . TRP A 1 108 ? 10.419 -25.884 2.697   1.000 70.156  0 112 TRP A CE2 1 ? 
ATOM   735  C CE3 . TRP A 1 108 ? 12.373 -24.677 1.940   1.000 69.732  0 112 TRP A CE3 1 ? 
ATOM   736  C CZ2 . TRP A 1 108 ? 9.729  -25.600 1.519   1.000 66.797  0 112 TRP A CZ2 1 ? 
ATOM   737  C CZ3 . TRP A 1 108 ? 11.684 -24.402 0.770   1.000 70.656  0 112 TRP A CZ3 1 ? 
ATOM   738  C CH2 . TRP A 1 108 ? 10.377 -24.858 0.571   1.000 66.200  0 112 TRP A CH2 1 ? 
ATOM   739  N N   . LYS A 1 109 ? 14.157 -28.329 6.626   1.000 60.589  0 113 LYS A N   1 ? 
ATOM   740  C CA  . LYS A 1 109 ? 13.640 -29.505 7.328   1.000 63.597  0 113 LYS A CA  1 ? 
ATOM   741  C C   . LYS A 1 109 ? 12.128 -29.378 7.537   1.000 66.221  0 113 LYS A C   1 ? 
ATOM   742  O O   . LYS A 1 109 ? 11.660 -28.458 8.217   1.000 60.981  0 113 LYS A O   1 ? 
ATOM   743  C CB  . LYS A 1 109 ? 14.358 -29.689 8.666   1.000 50.353  0 113 LYS A CB  1 ? 
ATOM   744  C CG  . LYS A 1 109 ? 14.163 -31.071 9.296   1.000 43.487  0 113 LYS A CG  1 ? 
ATOM   745  C CD  . LYS A 1 109 ? 14.885 -31.222 10.645  1.000 41.371  0 113 LYS A CD  1 ? 
ATOM   746  C CE  . LYS A 1 109 ? 14.995 -32.691 11.047  1.000 51.522  0 113 LYS A CE  1 ? 
ATOM   747  N NZ  . LYS A 1 109 ? 16.272 -33.348 10.584  1.000 53.038  0 113 LYS A NZ  1 ? 
ATOM   748  N N   . GLY A 1 110 ? 11.367 -30.297 6.954   1.000 66.208  0 114 GLY A N   1 ? 
ATOM   749  C CA  . GLY A 1 110 ? 9.926  -30.301 7.068   1.000 62.163  0 114 GLY A CA  1 ? 
ATOM   750  C C   . GLY A 1 110 ? 9.144  -29.930 5.814   1.000 61.728  0 114 GLY A C   1 ? 
ATOM   751  O O   . GLY A 1 110 ? 8.003  -29.463 5.942   1.000 59.507  0 114 GLY A O   1 ? 
ATOM   752  N N   . GLU A 1 111 ? 9.718  -30.112 4.623   1.000 63.766  0 115 GLU A N   1 ? 
ATOM   753  C CA  . GLU A 1 111 ? 8.998  -29.845 3.384   1.000 64.137  0 115 GLU A CA  1 ? 
ATOM   754  C C   . GLU A 1 111 ? 7.747  -30.708 3.299   1.000 63.542  0 115 GLU A C   1 ? 
ATOM   755  O O   . GLU A 1 111 ? 7.709  -31.842 3.786   1.000 66.400  0 115 GLU A O   1 ? 
ATOM   756  C CB  . GLU A 1 111 ? 9.879  -30.137 2.164   1.000 64.055  0 115 GLU A CB  1 ? 
ATOM   757  C CG  . GLU A 1 111 ? 11.231 -29.450 2.143   1.000 68.353  0 115 GLU A CG  1 ? 
ATOM   758  C CD  . GLU A 1 111 ? 12.118 -29.984 1.041   1.000 76.809  0 115 GLU A CD  1 ? 
ATOM   759  O OE1 . GLU A 1 111 ? 11.825 -31.089 0.544   1.000 80.825  0 115 GLU A OE1 1 ? 
ATOM   760  O OE2 . GLU A 1 111 ? 13.095 -29.300 0.657   1.000 83.760  0 115 GLU A OE2 1 ? 
ATOM   761  N N   . THR A 1 112 ? 6.712  -30.163 2.678   1.000 62.850  0 116 THR A N   1 ? 
ATOM   762  C CA  . THR A 1 112 ? 5.642  -31.018 2.201   1.000 67.045  0 116 THR A CA  1 ? 
ATOM   763  C C   . THR A 1 112 ? 6.042  -31.623 0.856   1.000 68.337  0 116 THR A C   1 ? 
ATOM   764  O O   . THR A 1 112 ? 7.008  -31.197 0.219   1.000 71.480  0 116 THR A O   1 ? 
ATOM   765  C CB  . THR A 1 112 ? 4.328  -30.242 2.095   1.000 68.390  0 116 THR A CB  1 ? 
ATOM   766  O OG1 . THR A 1 112 ? 3.239  -31.170 2.046   1.000 77.283  0 116 THR A OG1 1 ? 
ATOM   767  C CG2 . THR A 1 112 ? 4.298  -29.376 0.851   1.000 63.152  0 116 THR A CG2 1 ? 
ATOM   768  N N   . GLU A 1 113 ? 5.302  -32.651 0.433   1.000 68.069  0 117 GLU A N   1 ? 
ATOM   769  C CA  . GLU A 1 113 ? 5.610  -33.293 -0.843  1.000 74.801  0 117 GLU A CA  1 ? 
ATOM   770  C C   . GLU A 1 113 ? 5.535  -32.306 -2.005  1.000 78.596  0 117 GLU A C   1 ? 
ATOM   771  O O   . GLU A 1 113 ? 6.320  -32.405 -2.957  1.000 73.640  0 117 GLU A O   1 ? 
ATOM   772  C CB  . GLU A 1 113 ? 4.668  -34.478 -1.082  1.000 76.096  0 117 GLU A CB  1 ? 
ATOM   773  C CG  . GLU A 1 113 ? 4.746  -35.582 -0.028  1.000 78.204  0 117 GLU A CG  1 ? 
ATOM   774  C CD  . GLU A 1 113 ? 6.159  -36.112 0.172   1.000 83.368  0 117 GLU A CD  1 ? 
ATOM   775  O OE1 . GLU A 1 113 ? 6.872  -36.324 -0.831  1.000 86.539  0 117 GLU A OE1 1 ? 
ATOM   776  O OE2 . GLU A 1 113 ? 6.564  -36.319 1.334   1.000 85.381  0 117 GLU A OE2 1 ? 
ATOM   777  N N   . GLU A 1 114 ? 4.605  -31.347 -1.944  1.000 83.136  0 118 GLU A N   1 ? 
ATOM   778  C CA  . GLU A 1 114 ? 4.508  -30.346 -3.000  1.000 82.402  0 118 GLU A CA  1 ? 
ATOM   779  C C   . GLU A 1 114 ? 5.703  -29.401 -2.971  1.000 72.643  0 118 GLU A C   1 ? 
ATOM   780  O O   . GLU A 1 114 ? 6.259  -29.056 -4.020  1.000 69.753  0 118 GLU A O   1 ? 
ATOM   781  C CB  . GLU A 1 114 ? 3.198  -29.567 -2.867  1.000 81.594  0 118 GLU A CB  1 ? 
ATOM   782  C CG  . GLU A 1 114 ? 3.111  -28.342 -3.764  1.000 95.311  0 118 GLU A CG  1 ? 
ATOM   783  C CD  . GLU A 1 114 ? 3.274  -27.038 -2.997  1.000 107.350 0 118 GLU A CD  1 ? 
ATOM   784  O OE1 . GLU A 1 114 ? 4.017  -26.148 -3.468  1.000 108.468 0 118 GLU A OE1 1 ? 
ATOM   785  O OE2 . GLU A 1 114 ? 2.657  -26.905 -1.918  1.000 112.008 0 118 GLU A OE2 1 ? 
ATOM   786  N N   . GLU A 1 115 ? 6.107  -28.967 -1.778  1.000 63.837  0 119 GLU A N   1 ? 
ATOM   787  C CA  . GLU A 1 115 ? 7.280  -28.114 -1.673  1.000 57.978  0 119 GLU A CA  1 ? 
ATOM   788  C C   . GLU A 1 115 ? 8.521  -28.846 -2.154  1.000 67.419  0 119 GLU A C   1 ? 
ATOM   789  O O   . GLU A 1 115 ? 9.385  -28.253 -2.813  1.000 58.465  0 119 GLU A O   1 ? 
ATOM   790  C CB  . GLU A 1 115 ? 7.444  -27.645 -0.232  1.000 57.449  0 119 GLU A CB  1 ? 
ATOM   791  C CG  . GLU A 1 115 ? 6.345  -26.717 0.191   1.000 63.052  0 119 GLU A CG  1 ? 
ATOM   792  C CD  . GLU A 1 115 ? 6.293  -26.498 1.684   1.000 70.764  0 119 GLU A CD  1 ? 
ATOM   793  O OE1 . GLU A 1 115 ? 7.088  -27.116 2.428   1.000 64.121  0 119 GLU A OE1 1 ? 
ATOM   794  O OE2 . GLU A 1 115 ? 5.430  -25.704 2.113   1.000 81.076  0 119 GLU A OE2 1 ? 
ATOM   795  N N   . TYR A 1 116 ? 8.609  -30.147 -1.853  1.000 74.654  0 120 TYR A N   1 ? 
ATOM   796  C CA  . TYR A 1 116 ? 9.769  -30.950 -2.233  1.000 75.491  0 120 TYR A CA  1 ? 
ATOM   797  C C   . TYR A 1 116 ? 9.986  -30.928 -3.741  1.000 81.947  0 120 TYR A C   1 ? 
ATOM   798  O O   . TYR A 1 116 ? 11.107 -30.703 -4.218  1.000 80.349  0 120 TYR A O   1 ? 
ATOM   799  C CB  . TYR A 1 116 ? 9.590  -32.394 -1.750  1.000 68.753  0 120 TYR A CB  1 ? 
ATOM   800  C CG  . TYR A 1 116 ? 10.639 -33.348 -2.291  1.000 65.213  0 120 TYR A CG  1 ? 
ATOM   801  C CD1 . TYR A 1 116 ? 10.461 -34.016 -3.510  1.000 55.617  0 120 TYR A CD1 1 ? 
ATOM   802  C CD2 . TYR A 1 116 ? 11.814 -33.566 -1.594  1.000 66.397  0 120 TYR A CD2 1 ? 
ATOM   803  C CE1 . TYR A 1 116 ? 11.430 -34.871 -4.009  1.000 48.653  0 120 TYR A CE1 1 ? 
ATOM   804  C CE2 . TYR A 1 116 ? 12.783 -34.416 -2.077  1.000 64.945  0 120 TYR A CE2 1 ? 
ATOM   805  C CZ  . TYR A 1 116 ? 12.592 -35.071 -3.280  1.000 63.292  0 120 TYR A CZ  1 ? 
ATOM   806  O OH  . TYR A 1 116 ? 13.586 -35.920 -3.727  1.000 56.991  0 120 TYR A OH  1 ? 
ATOM   807  N N   . TRP A 1 117 ? 8.923  -31.202 -4.507  1.000 84.752  0 121 TRP A N   1 ? 
ATOM   808  C CA  . TRP A 1 117 ? 9.044  -31.285 -5.960  1.000 76.067  0 121 TRP A CA  1 ? 
ATOM   809  C C   . TRP A 1 117 ? 9.227  -29.911 -6.576  1.000 66.897  0 121 TRP A C   1 ? 
ATOM   810  O O   . TRP A 1 117 ? 9.850  -29.784 -7.638  1.000 60.747  0 121 TRP A O   1 ? 
ATOM   811  C CB  . TRP A 1 117 ? 7.818  -31.991 -6.547  1.000 70.211  0 121 TRP A CB  1 ? 
ATOM   812  C CG  . TRP A 1 117 ? 7.813  -33.452 -6.234  1.000 64.095  0 121 TRP A CG  1 ? 
ATOM   813  C CD1 . TRP A 1 117 ? 6.978  -34.110 -5.371  1.000 61.084  0 121 TRP A CD1 1 ? 
ATOM   814  C CD2 . TRP A 1 117 ? 8.723  -34.437 -6.746  1.000 53.543  0 121 TRP A CD2 1 ? 
ATOM   815  N NE1 . TRP A 1 117 ? 7.305  -35.447 -5.329  1.000 58.404  0 121 TRP A NE1 1 ? 
ATOM   816  C CE2 . TRP A 1 117 ? 8.371  -35.674 -6.163  1.000 55.801  0 121 TRP A CE2 1 ? 
ATOM   817  C CE3 . TRP A 1 117 ? 9.795  -34.394 -7.645  1.000 53.106  0 121 TRP A CE3 1 ? 
ATOM   818  C CZ2 . TRP A 1 117 ? 9.059  -36.865 -6.451  1.000 56.291  0 121 TRP A CZ2 1 ? 
ATOM   819  C CZ3 . TRP A 1 117 ? 10.475 -35.579 -7.932  1.000 60.326  0 121 TRP A CZ3 1 ? 
ATOM   820  C CH2 . TRP A 1 117 ? 10.102 -36.796 -7.335  1.000 57.470  0 121 TRP A CH2 1 ? 
ATOM   821  N N   . TRP A 1 118 ? 8.706  -28.875 -5.914  1.000 62.721  0 122 TRP A N   1 ? 
ATOM   822  C CA  . TRP A 1 118 ? 8.972  -27.511 -6.346  1.000 66.687  0 122 TRP A CA  1 ? 
ATOM   823  C C   . TRP A 1 118 ? 10.434 -27.145 -6.104  1.000 69.972  0 122 TRP A C   1 ? 
ATOM   824  O O   . TRP A 1 118 ? 11.072 -26.529 -6.965  1.000 74.980  0 122 TRP A O   1 ? 
ATOM   825  C CB  . TRP A 1 118 ? 8.017  -26.551 -5.629  1.000 63.766  0 122 TRP A CB  1 ? 
ATOM   826  C CG  . TRP A 1 118 ? 8.288  -25.102 -5.849  1.000 70.785  0 122 TRP A CG  1 ? 
ATOM   827  C CD1 . TRP A 1 118 ? 7.759  -24.302 -6.820  1.000 73.030  0 122 TRP A CD1 1 ? 
ATOM   828  C CD2 . TRP A 1 118 ? 9.152  -24.269 -5.071  1.000 81.183  0 122 TRP A CD2 1 ? 
ATOM   829  N NE1 . TRP A 1 118 ? 8.241  -23.020 -6.695  1.000 75.120  0 122 TRP A NE1 1 ? 
ATOM   830  C CE2 . TRP A 1 118 ? 9.095  -22.970 -5.626  1.000 82.686  0 122 TRP A CE2 1 ? 
ATOM   831  C CE3 . TRP A 1 118 ? 9.971  -24.494 -3.961  1.000 82.089  0 122 TRP A CE3 1 ? 
ATOM   832  C CZ2 . TRP A 1 118 ? 9.828  -21.902 -5.108  1.000 88.990  0 122 TRP A CZ2 1 ? 
ATOM   833  C CZ3 . TRP A 1 118 ? 10.696 -23.432 -3.444  1.000 86.168  0 122 TRP A CZ3 1 ? 
ATOM   834  C CH2 . TRP A 1 118 ? 10.623 -22.153 -4.017  1.000 87.287  0 122 TRP A CH2 1 ? 
ATOM   835  N N   . CYS A 1 119 ? 10.993 -27.550 -4.957  1.000 63.689  0 123 CYS A N   1 ? 
ATOM   836  C CA  . CYS A 1 119 ? 12.416 -27.342 -4.715  1.000 65.703  0 123 CYS A CA  1 ? 
ATOM   837  C C   . CYS A 1 119 ? 13.262 -28.016 -5.792  1.000 75.262  0 123 CYS A C   1 ? 
ATOM   838  O O   . CYS A 1 119 ? 14.250 -27.440 -6.269  1.000 77.391  0 123 CYS A O   1 ? 
ATOM   839  C CB  . CYS A 1 119 ? 12.786 -27.870 -3.333  1.000 62.036  0 123 CYS A CB  1 ? 
ATOM   840  S SG  . CYS A 1 119 ? 12.252 -26.842 -1.954  1.000 60.268  0 123 CYS A SG  1 ? 
ATOM   841  N N   . VAL A 1 120 ? 12.890 -29.241 -6.183  1.000 79.483  0 124 VAL A N   1 ? 
ATOM   842  C CA  . VAL A 1 120 ? 13.596 -29.942 -7.255  1.000 72.524  0 124 VAL A CA  1 ? 
ATOM   843  C C   . VAL A 1 120 ? 13.493 -29.149 -8.551  1.000 74.819  0 124 VAL A C   1 ? 
ATOM   844  O O   . VAL A 1 120 ? 14.493 -28.930 -9.246  1.000 65.460  0 124 VAL A O   1 ? 
ATOM   845  C CB  . VAL A 1 120 ? 13.038 -31.375 -7.404  1.000 63.837  0 124 VAL A CB  1 ? 
ATOM   846  C CG1 . VAL A 1 120 ? 13.487 -32.018 -8.703  1.000 57.257  0 124 VAL A CG1 1 ? 
ATOM   847  C CG2 . VAL A 1 120 ? 13.452 -32.237 -6.223  1.000 69.143  0 124 VAL A CG2 1 ? 
ATOM   848  N N   . GLU A 1 121 ? 12.283 -28.669 -8.868  1.000 80.481  0 125 GLU A N   1 ? 
ATOM   849  C CA  . GLU A 1 121 ? 12.063 -27.851 -10.060 1.000 80.120  0 125 GLU A CA  1 ? 
ATOM   850  C C   . GLU A 1 121 ? 12.918 -26.584 -10.055 1.000 84.950  0 125 GLU A C   1 ? 
ATOM   851  O O   . GLU A 1 121 ? 13.356 -26.119 -11.113 1.000 83.676  0 125 GLU A O   1 ? 
ATOM   852  C CB  . GLU A 1 121 ? 10.583 -27.485 -10.167 1.000 73.201  0 125 GLU A CB  1 ? 
ATOM   853  C CG  . GLU A 1 121 ? 9.684  -28.634 -10.592 1.000 77.470  0 125 GLU A CG  1 ? 
ATOM   854  C CD  . GLU A 1 121 ? 9.871  -29.011 -12.047 1.000 82.431  0 125 GLU A CD  1 ? 
ATOM   855  O OE1 . GLU A 1 121 ? 10.453 -28.201 -12.801 1.000 84.960  0 125 GLU A OE1 1 ? 
ATOM   856  O OE2 . GLU A 1 121 ? 9.448  -30.122 -12.433 1.000 82.702  0 125 GLU A OE2 1 ? 
ATOM   857  N N   . GLN A 1 122 ? 13.153 -26.002 -8.877  1.000 84.615  0 126 GLN A N   1 ? 
ATOM   858  C CA  . GLN A 1 122 ? 13.939 -24.775 -8.813  1.000 79.086  0 126 GLN A CA  1 ? 
ATOM   859  C C   . GLN A 1 122 ? 15.355 -24.975 -9.322  1.000 74.622  0 126 GLN A C   1 ? 
ATOM   860  O O   . GLN A 1 122 ? 15.934 -24.054 -9.907  1.000 81.491  0 126 GLN A O   1 ? 
ATOM   861  C CB  . GLN A 1 122 ? 13.975 -24.243 -7.384  1.000 76.006  0 126 GLN A CB  1 ? 
ATOM   862  C CG  . GLN A 1 122 ? 12.624 -23.965 -6.774  1.000 72.909  0 126 GLN A CG  1 ? 
ATOM   863  C CD  . GLN A 1 122 ? 11.682 -23.324 -7.757  1.000 78.775  0 126 GLN A CD  1 ? 
ATOM   864  O OE1 . GLN A 1 122 ? 11.666 -22.101 -7.912  1.000 81.052  0 126 GLN A OE1 1 ? 
ATOM   865  N NE2 . GLN A 1 122 ? 10.881 -24.144 -8.431  1.000 81.757  0 126 GLN A NE2 1 ? 
ATOM   866  N N   . THR A 1 123 ? 15.932 -26.157 -9.104  1.000 65.939  0 127 THR A N   1 ? 
ATOM   867  C CA  . THR A 1 123 ? 17.317 -26.394 -9.485  1.000 66.747  0 127 THR A CA  1 ? 
ATOM   868  C C   . THR A 1 123 ? 17.521 -26.440 -10.991 1.000 71.459  0 127 THR A C   1 ? 
ATOM   869  O O   . THR A 1 123 ? 18.675 -26.423 -11.436 1.000 76.246  0 127 THR A O   1 ? 
ATOM   870  C CB  . THR A 1 123 ? 17.837 -27.700 -8.862  1.000 62.789  0 127 THR A CB  1 ? 
ATOM   871  O OG1 . THR A 1 123 ? 17.233 -28.843 -9.489  1.000 54.925  0 127 THR A OG1 1 ? 
ATOM   872  C CG2 . THR A 1 123 ? 17.558 -27.731 -7.370  1.000 63.094  0 127 THR A CG2 1 ? 
ATOM   873  N N   . LEU A 1 124 ? 16.444 -26.520 -11.778 1.000 75.135  0 128 LEU A N   1 ? 
ATOM   874  C CA  . LEU A 1 124 ? 16.553 -26.729 -13.219 1.000 79.715  0 128 LEU A CA  1 ? 
ATOM   875  C C   . LEU A 1 124 ? 16.583 -25.436 -14.032 1.000 83.299  0 128 LEU A C   1 ? 
ATOM   876  O O   . LEU A 1 124 ? 16.785 -25.500 -15.250 1.000 73.264  0 128 LEU A O   1 ? 
ATOM   877  C CB  . LEU A 1 124 ? 15.408 -27.631 -13.723 1.000 75.493  0 128 LEU A CB  1 ? 
ATOM   878  C CG  . LEU A 1 124 ? 15.330 -29.050 -13.131 1.000 73.443  0 128 LEU A CG  1 ? 
ATOM   879  C CD1 . LEU A 1 124 ? 14.172 -29.855 -13.687 1.000 65.818  0 128 LEU A CD1 1 ? 
ATOM   880  C CD2 . LEU A 1 124 ? 16.640 -29.802 -13.334 1.000 75.293  0 128 LEU A CD2 1 ? 
ATOM   881  N N   . SER A 1 125 ? 16.403 -24.273 -13.404 1.000 93.461  0 129 SER A N   1 ? 
ATOM   882  C CA  . SER A 1 125 ? 16.448 -23.005 -14.123 1.000 100.667 0 129 SER A CA  1 ? 
ATOM   883  C C   . SER A 1 125 ? 16.887 -21.885 -13.187 1.000 100.233 0 129 SER A C   1 ? 
ATOM   884  O O   . SER A 1 125 ? 16.454 -21.824 -12.032 1.000 103.899 0 129 SER A O   1 ? 
ATOM   885  C CB  . SER A 1 125 ? 15.087 -22.668 -14.748 1.000 102.320 0 129 SER A CB  1 ? 
ATOM   886  O OG  . SER A 1 125 ? 14.161 -22.276 -13.755 1.000 100.994 0 129 SER A OG  1 ? 
ATOM   887  N N   . GLY A 1 126 ? 17.754 -21.008 -13.697 1.000 93.048  0 130 GLY A N   1 ? 
ATOM   888  C CA  . GLY A 1 126 ? 18.244 -19.876 -12.945 1.000 87.387  0 130 GLY A CA  1 ? 
ATOM   889  C C   . GLY A 1 126 ? 18.182 -18.590 -13.743 1.000 94.277  0 130 GLY A C   1 ? 
ATOM   890  O O   . GLY A 1 126 ? 17.831 -18.587 -14.928 1.000 92.966  0 130 GLY A O   1 ? 
ATOM   891  N N   . PRO A 1 127 ? 18.518 -17.469 -13.102 1.000 98.662  0 131 PRO A N   1 ? 
ATOM   892  C CA  . PRO A 1 127 ? 18.359 -16.163 -13.752 1.000 101.933 0 131 PRO A CA  1 ? 
ATOM   893  C C   . PRO A 1 127 ? 19.188 -16.071 -15.021 1.000 107.884 0 131 PRO A C   1 ? 
ATOM   894  O O   . PRO A 1 127 ? 20.298 -16.609 -15.094 1.000 105.752 0 131 PRO A O   1 ? 
ATOM   895  C CB  . PRO A 1 127 ? 18.858 -15.176 -12.691 1.000 99.617  0 131 PRO A CB  1 ? 
ATOM   896  C CG  . PRO A 1 127 ? 18.685 -15.886 -11.406 1.000 97.356  0 131 PRO A CG  1 ? 
ATOM   897  C CD  . PRO A 1 127 ? 18.963 -17.330 -11.710 1.000 97.975  0 131 PRO A CD  1 ? 
ATOM   898  N N   . ASN A 1 128 ? 18.628 -15.386 -16.025 1.000 113.411 0 132 ASN A N   1 ? 
ATOM   899  C CA  . ASN A 1 128 ? 19.247 -15.242 -17.343 1.000 114.137 0 132 ASN A CA  1 ? 
ATOM   900  C C   . ASN A 1 128 ? 19.454 -16.609 -18.006 1.000 104.189 0 132 ASN A C   1 ? 
ATOM   901  O O   . ASN A 1 128 ? 20.570 -16.998 -18.361 1.000 107.902 0 132 ASN A O   1 ? 
ATOM   902  C CB  . ASN A 1 128 ? 20.564 -14.459 -17.255 1.000 116.324 0 132 ASN A CB  1 ? 
ATOM   903  C CG  . ASN A 1 128 ? 20.366 -13.045 -16.749 1.000 118.862 0 132 ASN A CG  1 ? 
ATOM   904  O OD1 . ASN A 1 128 ? 19.259 -12.657 -16.362 1.000 123.333 0 132 ASN A OD1 1 ? 
ATOM   905  N ND2 . ASN A 1 128 ? 21.438 -12.260 -16.763 1.000 118.498 0 132 ASN A ND2 1 ? 
ATOM   906  N N   . GLY A 1 129 ? 18.349 -17.340 -18.143 1.000 91.358  0 133 GLY A N   1 ? 
ATOM   907  C CA  . GLY A 1 129 ? 18.334 -18.584 -18.893 1.000 83.057  0 133 GLY A CA  1 ? 
ATOM   908  C C   . GLY A 1 129 ? 19.314 -19.643 -18.431 1.000 84.371  0 133 GLY A C   1 ? 
ATOM   909  O O   . GLY A 1 129 ? 19.801 -20.428 -19.254 1.000 82.881  0 133 GLY A O   1 ? 
ATOM   910  N N   . TRP A 1 130 ? 19.623 -19.688 -17.136 1.000 87.703  0 134 TRP A N   1 ? 
ATOM   911  C CA  . TRP A 1 130 ? 20.574 -20.666 -16.614 1.000 90.392  0 134 TRP A CA  1 ? 
ATOM   912  C C   . TRP A 1 130 ? 20.004 -22.075 -16.743 1.000 82.505  0 134 TRP A C   1 ? 
ATOM   913  O O   . TRP A 1 130 ? 18.962 -22.396 -16.160 1.000 67.132  0 134 TRP A O   1 ? 
ATOM   914  C CB  . TRP A 1 130 ? 20.904 -20.345 -15.159 1.000 94.298  0 134 TRP A CB  1 ? 
ATOM   915  C CG  . TRP A 1 130 ? 21.938 -21.233 -14.493 1.000 91.042  0 134 TRP A CG  1 ? 
ATOM   916  C CD1 . TRP A 1 130 ? 23.238 -20.913 -14.232 1.000 83.771  0 134 TRP A CD1 1 ? 
ATOM   917  C CD2 . TRP A 1 130 ? 21.737 -22.548 -13.954 1.000 94.285  0 134 TRP A CD2 1 ? 
ATOM   918  N NE1 . TRP A 1 130 ? 23.865 -21.947 -13.582 1.000 84.181  0 134 TRP A NE1 1 ? 
ATOM   919  C CE2 . TRP A 1 130 ? 22.966 -22.964 -13.400 1.000 93.137  0 134 TRP A CE2 1 ? 
ATOM   920  C CE3 . TRP A 1 130 ? 20.641 -23.417 -13.894 1.000 95.054  0 134 TRP A CE3 1 ? 
ATOM   921  C CZ2 . TRP A 1 130 ? 23.130 -24.208 -12.799 1.000 99.438  0 134 TRP A CZ2 1 ? 
ATOM   922  C CZ3 . TRP A 1 130 ? 20.806 -24.651 -13.313 1.000 98.883  0 134 TRP A CZ3 1 ? 
ATOM   923  C CH2 . TRP A 1 130 ? 22.041 -25.037 -12.763 1.000 103.633 0 134 TRP A CH2 1 ? 
ATOM   924  N N   . THR A 1 131 ? 20.685 -22.906 -17.510 1.000 87.937  0 135 THR A N   1 ? 
ATOM   925  C CA  . THR A 1 131 ? 20.313 -24.291 -17.700 1.000 89.253  0 135 THR A CA  1 ? 
ATOM   926  C C   . THR A 1 131 ? 21.369 -25.182 -17.047 1.000 82.128  0 135 THR A C   1 ? 
ATOM   927  O O   . THR A 1 131 ? 22.514 -24.757 -16.879 1.000 81.049  0 135 THR A O   1 ? 
ATOM   928  C CB  . THR A 1 131 ? 20.177 -24.609 -19.202 1.000 90.071  0 135 THR A CB  1 ? 
ATOM   929  O OG1 . THR A 1 131 ? 19.276 -25.703 -19.398 1.000 90.616  0 135 THR A OG1 1 ? 
ATOM   930  C CG2 . THR A 1 131 ? 21.519 -24.962 -19.837 1.000 89.582  0 135 THR A CG2 1 ? 
ATOM   931  N N   . PRO A 1 132 ? 21.020 -26.385 -16.597 1.000 76.817  0 136 PRO A N   1 ? 
ATOM   932  C CA  . PRO A 1 132 ? 22.065 -27.326 -16.178 1.000 73.480  0 136 PRO A CA  1 ? 
ATOM   933  C C   . PRO A 1 132 ? 22.609 -28.132 -17.353 1.000 76.954  0 136 PRO A C   1 ? 
ATOM   934  O O   . PRO A 1 132 ? 21.883 -28.510 -18.281 1.000 74.322  0 136 PRO A O   1 ? 
ATOM   935  C CB  . PRO A 1 132 ? 21.356 -28.227 -15.156 1.000 55.012  0 136 PRO A CB  1 ? 
ATOM   936  C CG  . PRO A 1 132 ? 19.925 -28.139 -15.491 1.000 64.681  0 136 PRO A CG  1 ? 
ATOM   937  C CD  . PRO A 1 132 ? 19.684 -26.792 -16.124 1.000 74.212  0 136 PRO A CD  1 ? 
ATOM   938  N N   . ASN A 1 133 ? 23.926 -28.340 -17.328 1.000 77.833  0 137 ASN A N   1 ? 
ATOM   939  C CA  . ASN A 1 133 ? 24.577 -29.353 -18.145 1.000 79.691  0 137 ASN A CA  1 ? 
ATOM   940  C C   . ASN A 1 133 ? 25.014 -30.551 -17.310 1.000 77.065  0 137 ASN A C   1 ? 
ATOM   941  O O   . ASN A 1 133 ? 25.521 -31.531 -17.869 1.000 69.127  0 137 ASN A O   1 ? 
ATOM   942  C CB  . ASN A 1 133 ? 25.773 -28.753 -18.919 1.000 79.433  0 137 ASN A CB  1 ? 
ATOM   943  C CG  . ASN A 1 133 ? 26.725 -27.925 -18.036 1.000 73.761  0 137 ASN A CG  1 ? 
ATOM   944  O OD1 . ASN A 1 133 ? 27.179 -28.379 -16.980 1.000 63.813  0 137 ASN A OD1 1 ? 
ATOM   945  N ND2 . ASN A 1 133 ? 27.044 -26.709 -18.490 1.000 71.303  0 137 ASN A ND2 1 ? 
ATOM   946  N N   . LEU A 1 134 ? 24.789 -30.505 -15.987 1.000 79.667  0 138 LEU A N   1 ? 
ATOM   947  C CA  . LEU A 1 134 ? 25.192 -31.537 -15.038 1.000 70.140  0 138 LEU A CA  1 ? 
ATOM   948  C C   . LEU A 1 134 ? 24.047 -31.817 -14.076 1.000 67.824  0 138 LEU A C   1 ? 
ATOM   949  O O   . LEU A 1 134 ? 23.331 -30.896 -13.673 1.000 73.369  0 138 LEU A O   1 ? 
ATOM   950  C CB  . LEU A 1 134 ? 26.434 -31.094 -14.246 1.000 65.600  0 138 LEU A CB  1 ? 
ATOM   951  C CG  . LEU A 1 134 ? 27.749 -31.131 -15.037 1.000 67.916  0 138 LEU A CG  1 ? 
ATOM   952  C CD1 . LEU A 1 134 ? 28.899 -30.685 -14.170 1.000 73.330  0 138 LEU A CD1 1 ? 
ATOM   953  C CD2 . LEU A 1 134 ? 28.022 -32.518 -15.642 1.000 59.476  0 138 LEU A CD2 1 ? 
ATOM   954  N N   . LEU A 1 135 ? 23.872 -33.084 -13.707 1.000 66.392  0 139 LEU A N   1 ? 
ATOM   955  C CA  . LEU A 1 135 ? 22.926 -33.481 -12.666 1.000 66.608  0 139 LEU A CA  1 ? 
ATOM   956  C C   . LEU A 1 135 ? 23.683 -34.231 -11.574 1.000 58.591  0 139 LEU A C   1 ? 
ATOM   957  O O   . LEU A 1 135 ? 24.488 -35.118 -11.868 1.000 53.067  0 139 LEU A O   1 ? 
ATOM   958  C CB  . LEU A 1 135 ? 21.788 -34.353 -13.241 1.000 68.437  0 139 LEU A CB  1 ? 
ATOM   959  C CG  . LEU A 1 135 ? 20.742 -33.757 -14.207 1.000 64.202  0 139 LEU A CG  1 ? 
ATOM   960  C CD1 . LEU A 1 135 ? 19.966 -34.859 -14.897 1.000 57.796  0 139 LEU A CD1 1 ? 
ATOM   961  C CD2 . LEU A 1 135 ? 19.794 -32.791 -13.508 1.000 60.549  0 139 LEU A CD2 1 ? 
ATOM   962  N N   . LEU A 1 136 ? 23.453 -33.865 -10.320 1.000 51.098  0 140 LEU A N   1 ? 
ATOM   963  C CA  . LEU A 1 136 ? 24.060 -34.564 -9.194  1.000 46.571  0 140 LEU A CA  1 ? 
ATOM   964  C C   . LEU A 1 136 ? 22.920 -35.041 -8.303  1.000 52.993  0 140 LEU A C   1 ? 
ATOM   965  O O   . LEU A 1 136 ? 22.351 -34.262 -7.530  1.000 60.591  0 140 LEU A O   1 ? 
ATOM   966  C CB  . LEU A 1 136 ? 25.041 -33.663 -8.452  1.000 49.443  0 140 LEU A CB  1 ? 
ATOM   967  C CG  . LEU A 1 136 ? 26.109 -34.372 -7.612  1.000 50.424  0 140 LEU A CG  1 ? 
ATOM   968  C CD1 . LEU A 1 136 ? 27.243 -33.416 -7.254  1.000 53.101  0 140 LEU A CD1 1 ? 
ATOM   969  C CD2 . LEU A 1 136 ? 25.509 -34.984 -6.347  1.000 51.080  0 140 LEU A CD2 1 ? 
ATOM   970  N N   . ASP A 1 137 ? 22.605 -36.330 -8.387  1.000 56.170  0 141 ASP A N   1 ? 
ATOM   971  C CA  . ASP A 1 137 ? 21.326 -36.837 -7.904  1.000 64.271  0 141 ASP A CA  1 ? 
ATOM   972  C C   . ASP A 1 137 ? 21.531 -37.960 -6.900  1.000 60.131  0 141 ASP A C   1 ? 
ATOM   973  O O   . ASP A 1 137 ? 22.315 -38.882 -7.140  1.000 55.504  0 141 ASP A O   1 ? 
ATOM   974  C CB  . ASP A 1 137 ? 20.474 -37.320 -9.083  1.000 69.598  0 141 ASP A CB  1 ? 
ATOM   975  C CG  . ASP A 1 137 ? 19.053 -37.652 -8.684  1.000 68.706  0 141 ASP A CG  1 ? 
ATOM   976  O OD1 . ASP A 1 137 ? 18.628 -37.263 -7.577  1.000 70.601  0 141 ASP A OD1 1 ? 
ATOM   977  O OD2 . ASP A 1 137 ? 18.359 -38.291 -9.492  1.000 62.858  0 141 ASP A OD2 1 ? 
ATOM   978  N N   . ASP A 1 138 ? 20.805 -37.889 -5.789  1.000 59.707  0 142 ASP A N   1 ? 
ATOM   979  C CA  . ASP A 1 138 ? 20.852 -38.901 -4.735  1.000 57.099  0 142 ASP A CA  1 ? 
ATOM   980  C C   . ASP A 1 138 ? 19.459 -39.530 -4.633  1.000 49.861  0 142 ASP A C   1 ? 
ATOM   981  O O   . ASP A 1 138 ? 18.612 -39.066 -3.868  1.000 44.755  0 142 ASP A O   1 ? 
ATOM   982  C CB  . ASP A 1 138 ? 21.319 -38.273 -3.395  1.000 55.683  0 142 ASP A CB  1 ? 
ATOM   983  C CG  . ASP A 1 138 ? 21.351 -39.275 -2.231  1.000 57.170  0 142 ASP A CG  1 ? 
ATOM   984  O OD1 . ASP A 1 138 ? 20.914 -40.434 -2.403  1.000 58.320  0 142 ASP A OD1 1 ? 
ATOM   985  O OD2 . ASP A 1 138 ? 21.832 -38.900 -1.133  1.000 55.438  0 142 ASP A OD2 1 ? 
ATOM   986  N N   . GLY A 1 139 ? 19.234 -40.598 -5.396  1.000 52.093  0 143 GLY A N   1 ? 
ATOM   987  C CA  . GLY A 1 139 ? 18.019 -41.387 -5.305  1.000 55.136  0 143 GLY A CA  1 ? 
ATOM   988  C C   . GLY A 1 139 ? 17.166 -41.433 -6.560  1.000 60.089  0 143 GLY A C   1 ? 
ATOM   989  O O   . GLY A 1 139 ? 16.182 -42.188 -6.580  1.000 57.033  0 143 GLY A O   1 ? 
ATOM   990  N N   . GLY A 1 140 ? 17.471 -40.653 -7.606  1.000 62.100  0 144 GLY A N   1 ? 
ATOM   991  C CA  . GLY A 1 140 ? 16.795 -40.769 -8.884  1.000 61.897  0 144 GLY A CA  1 ? 
ATOM   992  C C   . GLY A 1 140 ? 15.666 -39.781 -9.129  1.000 64.239  0 144 GLY A C   1 ? 
ATOM   993  O O   . GLY A 1 140 ? 15.153 -39.728 -10.257 1.000 58.994  0 144 GLY A O   1 ? 
ATOM   994  N N   . ASP A 1 141 ? 15.267 -39.003 -8.115  1.000 65.208  0 145 ASP A N   1 ? 
ATOM   995  C CA  . ASP A 1 141 ? 14.134 -38.093 -8.266  1.000 61.865  0 145 ASP A CA  1 ? 
ATOM   996  C C   . ASP A 1 141 ? 14.446 -36.973 -9.251  1.000 64.624  0 145 ASP A C   1 ? 
ATOM   997  O O   . ASP A 1 141 ? 13.616 -36.641 -10.105 1.000 63.179  0 145 ASP A O   1 ? 
ATOM   998  C CB  . ASP A 1 141 ? 13.728 -37.520 -6.906  1.000 60.310  0 145 ASP A CB  1 ? 
ATOM   999  C CG  . ASP A 1 141 ? 12.823 -38.463 -6.119  1.000 68.129  0 145 ASP A CG  1 ? 
ATOM   1000 O OD1 . ASP A 1 141 ? 12.461 -39.527 -6.663  1.000 72.956  0 145 ASP A OD1 1 ? 
ATOM   1001 O OD2 . ASP A 1 141 ? 12.475 -38.149 -4.957  1.000 68.211  0 145 ASP A OD2 1 ? 
ATOM   1002 N N   . LEU A 1 142 ? 15.636 -36.372 -9.146  1.000 64.942  0 146 LEU A N   1 ? 
ATOM   1003 C CA  . LEU A 1 142 ? 16.021 -35.334 -10.100 1.000 62.115  0 146 LEU A CA  1 ? 
ATOM   1004 C C   . LEU A 1 142 ? 16.188 -35.909 -11.501 1.000 60.581  0 146 LEU A C   1 ? 
ATOM   1005 O O   . LEU A 1 142 ? 15.827 -35.261 -12.494 1.000 65.934  0 146 LEU A O   1 ? 
ATOM   1006 C CB  . LEU A 1 142 ? 17.309 -34.657 -9.648  1.000 60.349  0 146 LEU A CB  1 ? 
ATOM   1007 C CG  . LEU A 1 142 ? 17.821 -33.543 -10.564 1.000 66.147  0 146 LEU A CG  1 ? 
ATOM   1008 C CD1 . LEU A 1 142 ? 16.705 -32.585 -10.982 1.000 52.269  0 146 LEU A CD1 1 ? 
ATOM   1009 C CD2 . LEU A 1 142 ? 18.940 -32.798 -9.854  1.000 77.180  0 146 LEU A CD2 1 ? 
ATOM   1010 N N   . THR A 1 143 ? 16.725 -37.131 -11.591 1.000 50.846  0 147 THR A N   1 ? 
ATOM   1011 C CA  . THR A 1 143 ? 16.885 -37.806 -12.877 1.000 52.846  0 147 THR A CA  1 ? 
ATOM   1012 C C   . THR A 1 143 ? 15.540 -38.097 -13.539 1.000 64.387  0 147 THR A C   1 ? 
ATOM   1013 O O   . THR A 1 143 ? 15.395 -37.952 -14.760 1.000 64.195  0 147 THR A O   1 ? 
ATOM   1014 C CB  . THR A 1 143 ? 17.669 -39.105 -12.681 1.000 46.432  0 147 THR A CB  1 ? 
ATOM   1015 O OG1 . THR A 1 143 ? 18.990 -38.804 -12.206 1.000 45.316  0 147 THR A OG1 1 ? 
ATOM   1016 C CG2 . THR A 1 143 ? 17.748 -39.897 -13.983 1.000 46.932  0 147 THR A CG2 1 ? 
ATOM   1017 N N   . GLN A 1 144 ? 14.546 -38.519 -12.749 1.000 67.613  0 148 GLN A N   1 ? 
ATOM   1018 C CA  . GLN A 1 144 ? 13.236 -38.838 -13.308 1.000 70.124  0 148 GLN A CA  1 ? 
ATOM   1019 C C   . GLN A 1 144 ? 12.486 -37.574 -13.729 1.000 69.390  0 148 GLN A C   1 ? 
ATOM   1020 O O   . GLN A 1 144 ? 11.809 -37.564 -14.763 1.000 65.945  0 148 GLN A O   1 ? 
ATOM   1021 C CB  . GLN A 1 144 ? 12.431 -39.657 -12.292 1.000 74.140  0 148 GLN A CB  1 ? 
ATOM   1022 C CG  . GLN A 1 144 ? 10.921 -39.614 -12.484 1.000 78.899  0 148 GLN A CG  1 ? 
ATOM   1023 C CD  . GLN A 1 144 ? 10.170 -39.585 -11.173 1.000 73.796  0 148 GLN A CD  1 ? 
ATOM   1024 O OE1 . GLN A 1 144 ? 10.325 -40.477 -10.342 1.000 70.519  0 148 GLN A OE1 1 ? 
ATOM   1025 N NE2 . GLN A 1 144 ? 9.368  -38.545 -10.972 1.000 73.235  0 148 GLN A NE2 1 ? 
ATOM   1026 N N   . VAL A 1 145 ? 12.605 -36.496 -12.950 1.000 72.180  0 149 VAL A N   1 ? 
ATOM   1027 C CA  . VAL A 1 145 ? 11.935 -35.243 -13.292 1.000 73.269  0 149 VAL A CA  1 ? 
ATOM   1028 C C   . VAL A 1 145 ? 12.415 -34.736 -14.645 1.000 71.177  0 149 VAL A C   1 ? 
ATOM   1029 O O   . VAL A 1 145 ? 11.614 -34.349 -15.508 1.000 69.087  0 149 VAL A O   1 ? 
ATOM   1030 C CB  . VAL A 1 145 ? 12.172 -34.195 -12.190 1.000 73.619  0 149 VAL A CB  1 ? 
ATOM   1031 C CG1 . VAL A 1 145 ? 11.951 -32.785 -12.731 1.000 77.696  0 149 VAL A CG1 1 ? 
ATOM   1032 C CG2 . VAL A 1 145 ? 11.276 -34.469 -11.013 1.000 72.035  0 149 VAL A CG2 1 ? 
ATOM   1033 N N   . VAL A 1 146 ? 13.735 -34.732 -14.846 1.000 68.821  0 150 VAL A N   1 ? 
ATOM   1034 C CA  . VAL A 1 146 ? 14.286 -34.223 -16.092 1.000 74.914  0 150 VAL A CA  1 ? 
ATOM   1035 C C   . VAL A 1 146 ? 13.954 -35.160 -17.259 1.000 77.209  0 150 VAL A C   1 ? 
ATOM   1036 O O   . VAL A 1 146 ? 13.609 -34.698 -18.355 1.000 77.609  0 150 VAL A O   1 ? 
ATOM   1037 C CB  . VAL A 1 146 ? 15.799 -34.009 -15.926 1.000 72.896  0 150 VAL A CB  1 ? 
ATOM   1038 C CG1 . VAL A 1 146 ? 16.458 -33.860 -17.281 1.000 78.375  0 150 VAL A CG1 1 ? 
ATOM   1039 C CG2 . VAL A 1 146 ? 16.066 -32.795 -15.044 1.000 69.737  0 150 VAL A CG2 1 ? 
ATOM   1040 N N   . HIS A 1 147 ? 14.022 -36.482 -17.039 1.000 73.811  0 151 HIS A N   1 ? 
ATOM   1041 C CA  . HIS A 1 147 ? 13.750 -37.448 -18.106 1.000 65.663  0 151 HIS A CA  1 ? 
ATOM   1042 C C   . HIS A 1 147 ? 12.280 -37.421 -18.525 1.000 72.914  0 151 HIS A C   1 ? 
ATOM   1043 O O   . HIS A 1 147 ? 11.968 -37.543 -19.717 1.000 75.993  0 151 HIS A O   1 ? 
ATOM   1044 C CB  . HIS A 1 147 ? 14.135 -38.866 -17.658 1.000 54.772  0 151 HIS A CB  1 ? 
ATOM   1045 C CG  . HIS A 1 147 ? 15.551 -39.266 -17.976 1.000 57.091  0 151 HIS A CG  1 ? 
ATOM   1046 N ND1 . HIS A 1 147 ? 16.586 -39.147 -17.067 1.000 58.318  0 151 HIS A ND1 1 ? 
ATOM   1047 C CD2 . HIS A 1 147 ? 16.096 -39.818 -19.087 1.000 57.152  0 151 HIS A CD2 1 ? 
ATOM   1048 C CE1 . HIS A 1 147 ? 17.705 -39.590 -17.611 1.000 50.440  0 151 HIS A CE1 1 ? 
ATOM   1049 N NE2 . HIS A 1 147 ? 17.435 -40.005 -18.836 1.000 58.928  0 151 HIS A NE2 1 ? 
ATOM   1050 N N   . GLN A 1 148 ? 11.361 -37.270 -17.565 1.000 67.298  0 152 GLN A N   1 ? 
ATOM   1051 C CA  . GLN A 1 148 ? 9.933  -37.366 -17.849 1.000 64.895  0 152 GLN A CA  1 ? 
ATOM   1052 C C   . GLN A 1 148 ? 9.239  -36.020 -18.003 1.000 74.093  0 152 GLN A C   1 ? 
ATOM   1053 O O   . GLN A 1 148 ? 8.207  -35.949 -18.685 1.000 73.396  0 152 GLN A O   1 ? 
ATOM   1054 C CB  . GLN A 1 148 ? 9.219  -38.168 -16.754 1.000 67.429  0 152 GLN A CB  1 ? 
ATOM   1055 C CG  . GLN A 1 148 ? 9.876  -39.503 -16.423 1.000 73.096  0 152 GLN A CG  1 ? 
ATOM   1056 C CD  . GLN A 1 148 ? 9.174  -40.253 -15.294 1.000 69.772  0 152 GLN A CD  1 ? 
ATOM   1057 O OE1 . GLN A 1 148 ? 9.464  -41.430 -15.037 1.000 62.094  0 152 GLN A OE1 1 ? 
ATOM   1058 N NE2 . GLN A 1 148 ? 8.249  -39.572 -14.615 1.000 55.665  0 152 GLN A NE2 1 ? 
ATOM   1059 N N   . LYS A 1 149 ? 9.757  -34.946 -17.399 1.000 75.330  0 153 LYS A N   1 ? 
ATOM   1060 C CA  . LYS A 1 149 ? 9.084  -33.657 -17.504 1.000 80.160  0 153 LYS A CA  1 ? 
ATOM   1061 C C   . LYS A 1 149 ? 9.894  -32.547 -18.175 1.000 83.547  0 153 LYS A C   1 ? 
ATOM   1062 O O   . LYS A 1 149 ? 9.321  -31.494 -18.474 1.000 83.115  0 153 LYS A O   1 ? 
ATOM   1063 C CB  . LYS A 1 149 ? 8.610  -33.190 -16.114 1.000 78.809  0 153 LYS A CB  1 ? 
ATOM   1064 C CG  . LYS A 1 149 ? 7.394  -33.976 -15.598 1.000 77.815  0 153 LYS A CG  1 ? 
ATOM   1065 C CD  . LYS A 1 149 ? 7.483  -34.285 -14.110 1.000 81.041  0 153 LYS A CD  1 ? 
ATOM   1066 C CE  . LYS A 1 149 ? 6.701  -35.549 -13.731 1.000 81.915  0 153 LYS A CE  1 ? 
ATOM   1067 N NZ  . LYS A 1 149 ? 7.588  -36.733 -13.427 1.000 76.686  0 153 LYS A NZ  1 ? 
ATOM   1068 N N   . HIS A 1 150 ? 11.190 -32.734 -18.435 1.000 86.118  0 154 HIS A N   1 ? 
ATOM   1069 C CA  . HIS A 1 150 ? 11.972 -31.763 -19.208 1.000 83.557  0 154 HIS A CA  1 ? 
ATOM   1070 C C   . HIS A 1 150 ? 12.914 -32.491 -20.154 1.000 82.155  0 154 HIS A C   1 ? 
ATOM   1071 O O   . HIS A 1 150 ? 14.136 -32.366 -20.050 1.000 73.556  0 154 HIS A O   1 ? 
ATOM   1072 C CB  . HIS A 1 150 ? 12.755 -30.820 -18.293 1.000 81.715  0 154 HIS A CB  1 ? 
ATOM   1073 C CG  . HIS A 1 150 ? 11.985 -30.368 -17.095 1.000 80.312  0 154 HIS A CG  1 ? 
ATOM   1074 N ND1 . HIS A 1 150 ? 11.151 -29.271 -17.116 1.000 81.868  0 154 HIS A ND1 1 ? 
ATOM   1075 C CD2 . HIS A 1 150 ? 11.894 -30.887 -15.849 1.000 75.535  0 154 HIS A CD2 1 ? 
ATOM   1076 C CE1 . HIS A 1 150 ? 10.592 -29.124 -15.929 1.000 76.385  0 154 HIS A CE1 1 ? 
ATOM   1077 N NE2 . HIS A 1 150 ? 11.027 -30.090 -15.141 1.000 76.914  0 154 HIS A NE2 1 ? 
ATOM   1078 N N   . PRO A 1 151 ? 12.374 -33.251 -21.112 1.000 92.101  0 155 PRO A N   1 ? 
ATOM   1079 C CA  . PRO A 1 151 ? 13.249 -33.837 -22.142 1.000 96.190  0 155 PRO A CA  1 ? 
ATOM   1080 C C   . PRO A 1 151 ? 13.952 -32.785 -22.996 1.000 98.120  0 155 PRO A C   1 ? 
ATOM   1081 O O   . PRO A 1 151 ? 14.969 -33.096 -23.633 1.000 94.303  0 155 PRO A O   1 ? 
ATOM   1082 C CB  . PRO A 1 151 ? 12.291 -34.705 -22.972 1.000 94.264  0 155 PRO A CB  1 ? 
ATOM   1083 C CG  . PRO A 1 151 ? 10.947 -34.138 -22.729 1.000 93.682  0 155 PRO A CG  1 ? 
ATOM   1084 C CD  . PRO A 1 151 ? 10.950 -33.547 -21.357 1.000 91.843  0 155 PRO A CD  1 ? 
ATOM   1085 N N   . LYS A 1 152 ? 13.444 -31.547 -23.023 1.000 95.764  0 156 LYS A N   1 ? 
ATOM   1086 C CA  . LYS A 1 152 ? 14.173 -30.432 -23.618 1.000 90.948  0 156 LYS A CA  1 ? 
ATOM   1087 C C   . LYS A 1 152 ? 15.409 -30.048 -22.812 1.000 88.497  0 156 LYS A C   1 ? 
ATOM   1088 O O   . LYS A 1 152 ? 16.303 -29.391 -23.351 1.000 82.620  0 156 LYS A O   1 ? 
ATOM   1089 C CB  . LYS A 1 152 ? 13.241 -29.230 -23.760 1.000 92.527  0 156 LYS A CB  1 ? 
ATOM   1090 C CG  . LYS A 1 152 ? 12.382 -28.975 -22.528 1.000 93.822  0 156 LYS A CG  1 ? 
ATOM   1091 C CD  . LYS A 1 152 ? 11.989 -27.516 -22.370 1.000 101.412 0 156 LYS A CD  1 ? 
ATOM   1092 C CE  . LYS A 1 152 ? 11.371 -27.243 -21.010 1.000 102.831 0 156 LYS A CE  1 ? 
ATOM   1093 N NZ  . LYS A 1 152 ? 10.519 -28.356 -20.537 1.000 95.956  0 156 LYS A NZ  1 ? 
ATOM   1094 N N   . LEU A 1 153 ? 15.468 -30.432 -21.534 1.000 91.448  0 157 LEU A N   1 ? 
ATOM   1095 C CA  . LEU A 1 153 ? 16.654 -30.218 -20.711 1.000 87.887  0 157 LEU A CA  1 ? 
ATOM   1096 C C   . LEU A 1 153 ? 17.717 -31.279 -20.956 1.000 88.179  0 157 LEU A C   1 ? 
ATOM   1097 O O   . LEU A 1 153 ? 18.914 -30.972 -20.950 1.000 83.299  0 157 LEU A O   1 ? 
ATOM   1098 C CB  . LEU A 1 153 ? 16.271 -30.214 -19.236 1.000 86.800  0 157 LEU A CB  1 ? 
ATOM   1099 C CG  . LEU A 1 153 ? 16.197 -28.857 -18.563 1.000 88.229  0 157 LEU A CG  1 ? 
ATOM   1100 C CD1 . LEU A 1 153 ? 17.597 -28.227 -18.599 1.000 88.737  0 157 LEU A CD1 1 ? 
ATOM   1101 C CD2 . LEU A 1 153 ? 15.113 -27.976 -19.206 1.000 88.258  0 157 LEU A CD2 1 ? 
ATOM   1102 N N   . LEU A 1 154 ? 17.295 -32.530 -21.167 1.000 90.916  0 158 LEU A N   1 ? 
ATOM   1103 C CA  . LEU A 1 154 ? 18.229 -33.633 -21.366 1.000 90.321  0 158 LEU A CA  1 ? 
ATOM   1104 C C   . LEU A 1 154 ? 19.185 -33.388 -22.518 1.000 95.764  0 158 LEU A C   1 ? 
ATOM   1105 O O   . LEU A 1 154 ? 20.233 -34.039 -22.588 1.000 102.165 0 158 LEU A O   1 ? 
ATOM   1106 C CB  . LEU A 1 154 ? 17.476 -34.937 -21.636 1.000 89.008  0 158 LEU A CB  1 ? 
ATOM   1107 C CG  . LEU A 1 154 ? 16.634 -35.615 -20.562 1.000 84.431  0 158 LEU A CG  1 ? 
ATOM   1108 C CD1 . LEU A 1 154 ? 15.610 -36.526 -21.228 1.000 84.263  0 158 LEU A CD1 1 ? 
ATOM   1109 C CD2 . LEU A 1 154 ? 17.535 -36.404 -19.648 1.000 79.939  0 158 LEU A CD2 1 ? 
ATOM   1110 N N   . THR A 1 155 ? 18.843 -32.481 -23.433 1.000 95.104  0 159 THR A N   1 ? 
ATOM   1111 C CA  . THR A 1 155 ? 19.694 -32.286 -24.597 1.000 92.593  0 159 THR A CA  1 ? 
ATOM   1112 C C   . THR A 1 155 ? 21.030 -31.657 -24.217 1.000 85.589  0 159 THR A C   1 ? 
ATOM   1113 O O   . THR A 1 155 ? 22.067 -32.037 -24.771 1.000 85.021  0 159 THR A O   1 ? 
ATOM   1114 C CB  . THR A 1 155 ? 18.961 -31.451 -25.650 1.000 95.259  0 159 THR A CB  1 ? 
ATOM   1115 O OG1 . THR A 1 155 ? 19.768 -31.368 -26.829 1.000 93.243  0 159 THR A OG1 1 ? 
ATOM   1116 C CG2 . THR A 1 155 ? 18.655 -30.043 -25.137 1.000 96.446  0 159 THR A CG2 1 ? 
ATOM   1117 N N   . ALA A 1 156 ? 21.041 -30.738 -23.252 1.000 80.960  0 160 ALA A N   1 ? 
ATOM   1118 C CA  . ALA A 1 156 ? 22.258 -30.054 -22.845 1.000 77.665  0 160 ALA A CA  1 ? 
ATOM   1119 C C   . ALA A 1 156 ? 22.942 -30.706 -21.641 1.000 83.002  0 160 ALA A C   1 ? 
ATOM   1120 O O   . ALA A 1 156 ? 23.935 -30.160 -21.141 1.000 81.776  0 160 ALA A O   1 ? 
ATOM   1121 C CB  . ALA A 1 156 ? 21.951 -28.582 -22.555 1.000 75.635  0 160 ALA A CB  1 ? 
ATOM   1122 N N   . ILE A 1 157 ? 22.454 -31.864 -21.179 1.000 85.068  0 161 ILE A N   1 ? 
ATOM   1123 C CA  . ILE A 1 157 ? 22.988 -32.521 -19.983 1.000 86.163  0 161 ILE A CA  1 ? 
ATOM   1124 C C   . ILE A 1 157 ? 24.085 -33.503 -20.368 1.000 81.578  0 161 ILE A C   1 ? 
ATOM   1125 O O   . ILE A 1 157 ? 23.828 -34.497 -21.058 1.000 72.132  0 161 ILE A O   1 ? 
ATOM   1126 C CB  . ILE A 1 157 ? 21.892 -33.247 -19.190 1.000 84.576  0 161 ILE A CB  1 ? 
ATOM   1127 C CG1 . ILE A 1 157 ? 20.940 -32.241 -18.544 1.000 87.953  0 161 ILE A CG1 1 ? 
ATOM   1128 C CG2 . ILE A 1 157 ? 22.536 -34.161 -18.130 1.000 69.432  0 161 ILE A CG2 1 ? 
ATOM   1129 C CD1 . ILE A 1 157 ? 19.728 -32.875 -17.939 1.000 88.971  0 161 ILE A CD1 1 ? 
ATOM   1130 N N   . LYS A 1 158 ? 25.298 -33.247 -19.873 1.000 84.744  0 162 LYS A N   1 ? 
ATOM   1131 C CA  . LYS A 1 158 ? 26.414 -34.154 -20.116 1.000 83.444  0 162 LYS A CA  1 ? 
ATOM   1132 C C   . LYS A 1 158 ? 26.236 -35.467 -19.354 1.000 83.378  0 162 LYS A C   1 ? 
ATOM   1133 O O   . LYS A 1 158 ? 26.430 -36.548 -19.923 1.000 86.342  0 162 LYS A O   1 ? 
ATOM   1134 C CB  . LYS A 1 158 ? 27.730 -33.459 -19.750 1.000 73.064  0 162 LYS A CB  1 ? 
ATOM   1135 C CG  . LYS A 1 158 ? 28.001 -32.221 -20.604 1.000 68.587  0 162 LYS A CG  1 ? 
ATOM   1136 C CD  . LYS A 1 158 ? 29.458 -31.827 -20.605 1.000 69.614  0 162 LYS A CD  1 ? 
ATOM   1137 C CE  . LYS A 1 158 ? 29.857 -31.117 -21.886 1.000 70.048  0 162 LYS A CE  1 ? 
ATOM   1138 N NZ  . LYS A 1 158 ? 28.775 -31.096 -22.909 1.000 80.531  0 162 LYS A NZ  1 ? 
ATOM   1139 N N   . GLY A 1 159 ? 25.843 -35.402 -18.081 1.000 77.565  0 163 GLY A N   1 ? 
ATOM   1140 C CA  . GLY A 1 159 ? 25.606 -36.629 -17.338 1.000 70.253  0 163 GLY A CA  1 ? 
ATOM   1141 C C   . GLY A 1 159 ? 25.033 -36.394 -15.954 1.000 62.842  0 163 GLY A C   1 ? 
ATOM   1142 O O   . GLY A 1 159 ? 24.951 -35.265 -15.461 1.000 55.386  0 163 GLY A O   1 ? 
ATOM   1143 N N   . VAL A 1 160 ? 24.632 -37.502 -15.334 1.000 65.608  0 164 VAL A N   1 ? 
ATOM   1144 C CA  . VAL A 1 160 ? 24.193 -37.543 -13.944 1.000 67.763  0 164 VAL A CA  1 ? 
ATOM   1145 C C   . VAL A 1 160 ? 25.126 -38.466 -13.161 1.000 71.638  0 164 VAL A C   1 ? 
ATOM   1146 O O   . VAL A 1 160 ? 25.565 -39.504 -13.672 1.000 69.979  0 164 VAL A O   1 ? 
ATOM   1147 C CB  . VAL A 1 160 ? 22.722 -38.007 -13.827 1.000 66.082  0 164 VAL A CB  1 ? 
ATOM   1148 C CG1 . VAL A 1 160 ? 22.532 -39.407 -14.422 1.000 68.729  0 164 VAL A CG1 1 ? 
ATOM   1149 C CG2 . VAL A 1 160 ? 22.244 -37.971 -12.374 1.000 55.046  0 164 VAL A CG2 1 ? 
ATOM   1150 N N   . SER A 1 161 ? 25.452 -38.073 -11.929 1.000 65.179  0 165 SER A N   1 ? 
ATOM   1151 C CA  . SER A 1 161 ? 26.175 -38.927 -10.998 1.000 61.960  0 165 SER A CA  1 ? 
ATOM   1152 C C   . SER A 1 161 ? 25.235 -39.246 -9.848  1.000 66.008  0 165 SER A C   1 ? 
ATOM   1153 O O   . SER A 1 161 ? 24.753 -38.340 -9.162  1.000 69.753  0 165 SER A O   1 ? 
ATOM   1154 C CB  . SER A 1 161 ? 27.461 -38.261 -10.507 1.000 61.439  0 165 SER A CB  1 ? 
ATOM   1155 O OG  . SER A 1 161 ? 27.287 -36.865 -10.376 1.000 61.118  0 165 SER A OG  1 ? 
ATOM   1156 N N   . GLU A 1 162 ? 24.957 -40.529 -9.662  1.000 69.979  0 166 GLU A N   1 ? 
ATOM   1157 C CA  . GLU A 1 162 ? 23.950 -40.990 -8.719  1.000 61.923  0 166 GLU A CA  1 ? 
ATOM   1158 C C   . GLU A 1 162 ? 24.639 -41.481 -7.456  1.000 53.422  0 166 GLU A C   1 ? 
ATOM   1159 O O   . GLU A 1 162 ? 25.630 -42.218 -7.524  1.000 55.662  0 166 GLU A O   1 ? 
ATOM   1160 C CB  . GLU A 1 162 ? 23.097 -42.095 -9.340  1.000 56.236  0 166 GLU A CB  1 ? 
ATOM   1161 C CG  . GLU A 1 162 ? 22.286 -42.900 -8.358  1.000 55.809  0 166 GLU A CG  1 ? 
ATOM   1162 C CD  . GLU A 1 162 ? 21.304 -42.057 -7.595  1.000 58.615  0 166 GLU A CD  1 ? 
ATOM   1163 O OE1 . GLU A 1 162 ? 21.378 -42.063 -6.345  1.000 59.865  0 166 GLU A OE1 1 ? 
ATOM   1164 O OE2 . GLU A 1 162 ? 20.459 -41.404 -8.247  1.000 58.318  0 166 GLU A OE2 1 ? 
ATOM   1165 N N   . GLU A 1 163 ? 24.107 -41.078 -6.312  1.000 41.910  0 167 GLU A N   1 ? 
ATOM   1166 C CA  . GLU A 1 163 ? 24.772 -41.303 -5.044  1.000 42.918  0 167 GLU A CA  1 ? 
ATOM   1167 C C   . GLU A 1 163 ? 24.409 -42.637 -4.390  1.000 52.209  0 167 GLU A C   1 ? 
ATOM   1168 O O   . GLU A 1 163 ? 25.251 -43.205 -3.683  1.000 52.946  0 167 GLU A O   1 ? 
ATOM   1169 C CB  . GLU A 1 163 ? 24.461 -40.130 -4.097  1.000 43.629  0 167 GLU A CB  1 ? 
ATOM   1170 C CG  . GLU A 1 163 ? 24.761 -40.342 -2.612  1.000 43.160  0 167 GLU A CG  1 ? 
ATOM   1171 C CD  . GLU A 1 163 ? 26.174 -39.915 -2.220  1.000 49.682  0 167 GLU A CD  1 ? 
ATOM   1172 O OE1 . GLU A 1 163 ? 26.463 -39.863 -0.997  1.000 42.905  0 167 GLU A OE1 1 ? 
ATOM   1173 O OE2 . GLU A 1 163 ? 26.993 -39.645 -3.135  1.000 53.385  0 167 GLU A OE2 1 ? 
ATOM   1174 N N   . THR A 1 164 ? 23.208 -43.186 -4.607  1.000 53.383  0 168 THR A N   1 ? 
ATOM   1175 C CA  . THR A 1 164 ? 22.752 -44.259 -3.727  1.000 51.864  0 168 THR A CA  1 ? 
ATOM   1176 C C   . THR A 1 164 ? 22.173 -45.457 -4.474  1.000 53.580  0 168 THR A C   1 ? 
ATOM   1177 O O   . THR A 1 164 ? 21.744 -45.366 -5.635  1.000 47.732  0 168 THR A O   1 ? 
ATOM   1178 C CB  . THR A 1 164 ? 21.725 -43.749 -2.714  1.000 37.183  0 168 THR A CB  1 ? 
ATOM   1179 O OG1 . THR A 1 164 ? 21.760 -44.597 -1.562  1.000 35.731  0 168 THR A OG1 1 ? 
ATOM   1180 C CG2 . THR A 1 164 ? 20.333 -43.742 -3.311  1.000 35.281  0 168 THR A CG2 1 ? 
ATOM   1181 N N   . THR A 1 165 ? 22.169 -46.590 -3.748  1.000 47.887  0 169 THR A N   1 ? 
ATOM   1182 C CA  . THR A 1 165 ? 21.820 -47.883 -4.334  1.000 44.200  0 169 THR A CA  1 ? 
ATOM   1183 C C   . THR A 1 165 ? 20.483 -47.817 -5.023  1.000 43.376  0 169 THR A C   1 ? 
ATOM   1184 O O   . THR A 1 165 ? 20.319 -48.335 -6.130  1.000 49.424  0 169 THR A O   1 ? 
ATOM   1185 C CB  . THR A 1 165 ? 21.760 -48.968 -3.259  1.000 37.010  0 169 THR A CB  1 ? 
ATOM   1186 O OG1 . THR A 1 165 ? 22.752 -48.710 -2.270  1.000 39.078  0 169 THR A OG1 1 ? 
ATOM   1187 C CG2 . THR A 1 165 ? 21.998 -50.356 -3.867  1.000 32.025  0 169 THR A CG2 1 ? 
ATOM   1188 N N   . THR A 1 166 ? 19.516 -47.174 -4.376  1.000 50.788  0 170 THR A N   1 ? 
ATOM   1189 C CA  . THR A 1 166 ? 18.167 -47.146 -4.907  1.000 53.785  0 170 THR A CA  1 ? 
ATOM   1190 C C   . THR A 1 166 ? 18.125 -46.337 -6.200  1.000 51.430  0 170 THR A C   1 ? 
ATOM   1191 O O   . THR A 1 166 ? 17.519 -46.771 -7.189  1.000 50.906  0 170 THR A O   1 ? 
ATOM   1192 C CB  . THR A 1 166 ? 17.208 -46.609 -3.832  1.000 60.986  0 170 THR A CB  1 ? 
ATOM   1193 O OG1 . THR A 1 166 ? 15.901 -47.131 -4.076  1.000 66.945  0 170 THR A OG1 1 ? 
ATOM   1194 C CG2 . THR A 1 166 ? 17.145 -45.058 -3.819  1.000 65.995  0 170 THR A CG2 1 ? 
ATOM   1195 N N   . GLY A 1 167 ? 18.825 -45.198 -6.235  1.000 47.895  0 171 GLY A N   1 ? 
ATOM   1196 C CA  . GLY A 1 167 ? 18.896 -44.412 -7.453  1.000 50.040  0 171 GLY A CA  1 ? 
ATOM   1197 C C   . GLY A 1 167 ? 19.612 -45.121 -8.577  1.000 51.946  0 171 GLY A C   1 ? 
ATOM   1198 O O   . GLY A 1 167 ? 19.314 -44.864 -9.751  1.000 52.627  0 171 GLY A O   1 ? 
ATOM   1199 N N   . VAL A 1 168 ? 20.539 -46.019 -8.238  1.000 37.220  0 172 VAL A N   1 ? 
ATOM   1200 C CA  . VAL A 1 168 ? 21.236 -46.807 -9.245  1.000 40.979  0 172 VAL A CA  1 ? 
ATOM   1201 C C   . VAL A 1 168 ? 20.325 -47.884 -9.819  1.000 55.375  0 172 VAL A C   1 ? 
ATOM   1202 O O   . VAL A 1 168 ? 20.306 -48.113 -11.036 1.000 57.199  0 172 VAL A O   1 ? 
ATOM   1203 C CB  . VAL A 1 168 ? 22.518 -47.404 -8.642  1.000 39.223  0 172 VAL A CB  1 ? 
ATOM   1204 C CG1 . VAL A 1 168 ? 23.244 -48.293 -9.648  1.000 35.854  0 172 VAL A CG1 1 ? 
ATOM   1205 C CG2 . VAL A 1 168 ? 23.423 -46.294 -8.138  1.000 35.460  0 172 VAL A CG2 1 ? 
ATOM   1206 N N   . ALA A 1 169 ? 19.551 -48.556 -8.962  1.000 56.620  0 173 ALA A N   1 ? 
ATOM   1207 C CA  . ALA A 1 169 ? 18.572 -49.520 -9.459  1.000 55.201  0 173 ALA A CA  1 ? 
ATOM   1208 C C   . ALA A 1 169 ? 17.591 -48.867 -10.428 1.000 59.828  0 173 ALA A C   1 ? 
ATOM   1209 O O   . ALA A 1 169 ? 17.177 -49.490 -11.417 1.000 59.991  0 173 ALA A O   1 ? 
ATOM   1210 C CB  . ALA A 1 169 ? 17.820 -50.162 -8.296  1.000 41.676  0 173 ALA A CB  1 ? 
ATOM   1211 N N   . ARG A 1 170 ? 17.216 -47.607 -10.165 1.000 59.715  0 174 ARG A N   1 ? 
ATOM   1212 C CA  . ARG A 1 170 ? 16.289 -46.890 -11.041 1.000 63.021  0 174 ARG A CA  1 ? 
ATOM   1213 C C   . ARG A 1 170 ? 16.949 -46.485 -12.361 1.000 59.812  0 174 ARG A C   1 ? 
ATOM   1214 O O   . ARG A 1 170 ? 16.282 -46.441 -13.404 1.000 55.725  0 174 ARG A O   1 ? 
ATOM   1215 C CB  . ARG A 1 170 ? 15.728 -45.660 -10.315 1.000 61.465  0 174 ARG A CB  1 ? 
ATOM   1216 C CG  . ARG A 1 170 ? 14.821 -45.975 -9.123  1.000 50.685  0 174 ARG A CG  1 ? 
ATOM   1217 C CD  . ARG A 1 170 ? 14.396 -44.707 -8.375  1.000 51.069  0 174 ARG A CD  1 ? 
ATOM   1218 N NE  . ARG A 1 170 ? 13.460 -43.907 -9.162  1.000 58.644  0 174 ARG A NE  1 ? 
ATOM   1219 C CZ  . ARG A 1 170 ? 13.026 -42.698 -8.821  1.000 56.907  0 174 ARG A CZ  1 ? 
ATOM   1220 N NH1 . ARG A 1 170 ? 13.446 -42.135 -7.695  1.000 62.268  0 174 ARG A NH1 1 ? 
ATOM   1221 N NH2 . ARG A 1 170 ? 12.170 -42.055 -9.607  1.000 46.427  0 174 ARG A NH2 1 ? 
ATOM   1222 N N   . LEU A 1 171 ? 18.247 -46.183 -12.335 1.000 56.315  0 175 LEU A N   1 ? 
ATOM   1223 C CA  . LEU A 1 171 ? 18.986 -46.000 -13.575 1.000 57.223  0 175 LEU A CA  1 ? 
ATOM   1224 C C   . LEU A 1 171 ? 18.950 -47.261 -14.431 1.000 65.616  0 175 LEU A C   1 ? 
ATOM   1225 O O   . LEU A 1 171 ? 18.842 -47.185 -15.664 1.000 58.483  0 175 LEU A O   1 ? 
ATOM   1226 C CB  . LEU A 1 171 ? 20.423 -45.599 -13.250 1.000 47.782  0 175 LEU A CB  1 ? 
ATOM   1227 C CG  . LEU A 1 171 ? 20.477 -44.103 -12.973 1.000 55.986  0 175 LEU A CG  1 ? 
ATOM   1228 C CD1 . LEU A 1 171 ? 21.476 -43.786 -11.896 1.000 40.507  0 175 LEU A CD1 1 ? 
ATOM   1229 C CD2 . LEU A 1 171 ? 20.763 -43.346 -14.273 1.000 64.329  0 175 LEU A CD2 1 ? 
ATOM   1230 N N   . TYR A 1 172 ? 19.018 -48.432 -13.784 1.000 70.208  0 176 TYR A N   1 ? 
ATOM   1231 C CA  . TYR A 1 172 ? 19.114 -49.704 -14.496 1.000 72.127  0 176 TYR A CA  1 ? 
ATOM   1232 C C   . TYR A 1 172 ? 17.814 -50.059 -15.201 1.000 71.153  0 176 TYR A C   1 ? 
ATOM   1233 O O   . TYR A 1 172 ? 17.830 -50.496 -16.357 1.000 66.495  0 176 TYR A O   1 ? 
ATOM   1234 C CB  . TYR A 1 172 ? 19.503 -50.820 -13.530 1.000 75.138  0 176 TYR A CB  1 ? 
ATOM   1235 C CG  . TYR A 1 172 ? 20.984 -50.952 -13.377 1.000 86.779  0 176 TYR A CG  1 ? 
ATOM   1236 C CD1 . TYR A 1 172 ? 21.804 -51.036 -14.494 1.000 95.706  0 176 TYR A CD1 1 ? 
ATOM   1237 C CD2 . TYR A 1 172 ? 21.573 -50.971 -12.117 1.000 87.508  0 176 TYR A CD2 1 ? 
ATOM   1238 C CE1 . TYR A 1 172 ? 23.170 -51.153 -14.360 1.000 99.891  0 176 TYR A CE1 1 ? 
ATOM   1239 C CE2 . TYR A 1 172 ? 22.940 -51.081 -11.972 1.000 89.424  0 176 TYR A CE2 1 ? 
ATOM   1240 C CZ  . TYR A 1 172 ? 23.736 -51.166 -13.096 1.000 99.046  0 176 TYR A CZ  1 ? 
ATOM   1241 O OH  . TYR A 1 172 ? 25.102 -51.277 -12.958 1.000 106.747 0 176 TYR A OH  1 ? 
ATOM   1242 N N   . GLU A 1 173 ? 16.677 -49.914 -14.512 1.000 71.838  0 177 GLU A N   1 ? 
ATOM   1243 C CA  . GLU A 1 173 ? 15.408 -50.185 -15.176 1.000 72.532  0 177 GLU A CA  1 ? 
ATOM   1244 C C   . GLU A 1 173 ? 15.190 -49.227 -16.344 1.000 62.386  0 177 GLU A C   1 ? 
ATOM   1245 O O   . GLU A 1 173 ? 14.635 -49.626 -17.378 1.000 57.904  0 177 GLU A O   1 ? 
ATOM   1246 C CB  . GLU A 1 173 ? 14.251 -50.121 -14.172 1.000 80.589  0 177 GLU A CB  1 ? 
ATOM   1247 C CG  . GLU A 1 173 ? 13.242 -51.255 -14.363 1.000 90.921  0 177 GLU A CG  1 ? 
ATOM   1248 C CD  . GLU A 1 173 ? 11.821 -50.900 -13.942 1.000 98.864  0 177 GLU A CD  1 ? 
ATOM   1249 O OE1 . GLU A 1 173 ? 11.612 -49.841 -13.310 1.000 99.707  0 177 GLU A OE1 1 ? 
ATOM   1250 O OE2 . GLU A 1 173 ? 10.903 -51.683 -14.269 1.000 101.773 0 177 GLU A OE2 1 ? 
ATOM   1251 N N   . MET A 1 174 ? 15.655 -47.977 -16.214 1.000 54.770  0 178 MET A N   1 ? 
ATOM   1252 C CA  . MET A 1 174 ? 15.644 -47.048 -17.341 1.000 55.683  0 178 MET A CA  1 ? 
ATOM   1253 C C   . MET A 1 174 ? 16.465 -47.580 -18.511 1.000 62.658  0 178 MET A C   1 ? 
ATOM   1254 O O   . MET A 1 174 ? 15.975 -47.654 -19.647 1.000 63.200  0 178 MET A O   1 ? 
ATOM   1255 C CB  . MET A 1 174 ? 16.180 -45.690 -16.908 1.000 55.207  0 178 MET A CB  1 ? 
ATOM   1256 C CG  . MET A 1 174 ? 15.201 -44.841 -16.148 1.000 67.906  0 178 MET A CG  1 ? 
ATOM   1257 S SD  . MET A 1 174 ? 15.783 -43.136 -16.097 1.000 83.405  0 178 MET A SD  1 ? 
ATOM   1258 C CE  . MET A 1 174 ? 17.433 -43.361 -15.433 1.000 82.223  0 178 MET A CE  1 ? 
ATOM   1259 N N   . ALA A 1 175 ? 17.728 -47.941 -18.257 1.000 65.416  0 179 ALA A N   1 ? 
ATOM   1260 C CA  . ALA A 1 175 ? 18.573 -48.469 -19.326 1.000 64.160  0 179 ALA A CA  1 ? 
ATOM   1261 C C   . ALA A 1 175 ? 17.960 -49.724 -19.946 1.000 65.750  0 179 ALA A C   1 ? 
ATOM   1262 O O   . ALA A 1 175 ? 18.015 -49.911 -21.169 1.000 72.746  0 179 ALA A O   1 ? 
ATOM   1263 C CB  . ALA A 1 175 ? 19.977 -48.751 -18.790 1.000 59.533  0 179 ALA A CB  1 ? 
ATOM   1264 N N   . LYS A 1 176 ? 17.333 -50.570 -19.119 1.000 61.510  0 180 LYS A N   1 ? 
ATOM   1265 C CA  . LYS A 1 176 ? 16.769 -51.836 -19.585 1.000 67.334  0 180 LYS A CA  1 ? 
ATOM   1266 C C   . LYS A 1 176 ? 15.597 -51.630 -20.547 1.000 71.003  0 180 LYS A C   1 ? 
ATOM   1267 O O   . LYS A 1 176 ? 15.376 -52.461 -21.435 1.000 69.029  0 180 LYS A O   1 ? 
ATOM   1268 C CB  . LYS A 1 176 ? 16.347 -52.685 -18.375 1.000 72.703  0 180 LYS A CB  1 ? 
ATOM   1269 C CG  . LYS A 1 176 ? 15.551 -53.950 -18.697 1.000 80.028  0 180 LYS A CG  1 ? 
ATOM   1270 C CD  . LYS A 1 176 ? 14.624 -54.353 -17.550 1.000 78.949  0 180 LYS A CD  1 ? 
ATOM   1271 C CE  . LYS A 1 176 ? 14.682 -55.848 -17.265 1.000 74.001  0 180 LYS A CE  1 ? 
ATOM   1272 N NZ  . LYS A 1 176 ? 13.496 -56.267 -16.465 1.000 70.843  0 180 LYS A NZ  1 ? 
ATOM   1273 N N   . HIS A 1 177 ? 14.840 -50.540 -20.399 1.000 74.825  0 181 HIS A N   1 ? 
ATOM   1274 C CA  . HIS A 1 177 ? 13.739 -50.225 -21.304 1.000 79.515  0 181 HIS A CA  1 ? 
ATOM   1275 C C   . HIS A 1 177 ? 14.070 -49.040 -22.207 1.000 81.836  0 181 HIS A C   1 ? 
ATOM   1276 O O   . HIS A 1 177 ? 13.174 -48.306 -22.631 1.000 91.100  0 181 HIS A O   1 ? 
ATOM   1277 C CB  . HIS A 1 177 ? 12.452 -49.961 -20.522 1.000 76.349  0 181 HIS A CB  1 ? 
ATOM   1278 C CG  . HIS A 1 177 ? 12.057 -51.088 -19.620 1.000 75.959  0 181 HIS A CG  1 ? 
ATOM   1279 N ND1 . HIS A 1 177 ? 12.375 -51.113 -18.278 1.000 74.780  0 181 HIS A ND1 1 ? 
ATOM   1280 C CD2 . HIS A 1 177 ? 11.381 -52.233 -19.868 1.000 74.769  0 181 HIS A CD2 1 ? 
ATOM   1281 C CE1 . HIS A 1 177 ? 11.915 -52.228 -17.739 1.000 72.722  0 181 HIS A CE1 1 ? 
ATOM   1282 N NE2 . HIS A 1 177 ? 11.308 -52.924 -18.683 1.000 76.025  0 181 HIS A NE2 1 ? 
ATOM   1283 N N   . GLY A 1 178 ? 15.355 -48.839 -22.494 1.000 74.240  0 182 GLY A N   1 ? 
ATOM   1284 C CA  . GLY A 1 178 ? 15.791 -47.778 -23.377 1.000 69.700  0 182 GLY A CA  1 ? 
ATOM   1285 C C   . GLY A 1 178 ? 15.318 -46.398 -22.975 1.000 73.317  0 182 GLY A C   1 ? 
ATOM   1286 O O   . GLY A 1 178 ? 15.165 -45.531 -23.836 1.000 75.130  0 182 GLY A O   1 ? 
ATOM   1287 N N   . GLN A 1 179 ? 15.080 -46.175 -21.681 1.000 78.480  0 183 GLN A N   1 ? 
ATOM   1288 C CA  . GLN A 1 179 ? 14.622 -44.874 -21.203 1.000 84.386  0 183 GLN A CA  1 ? 
ATOM   1289 C C   . GLN A 1 179 ? 15.756 -43.965 -20.730 1.000 78.004  0 183 GLN A C   1 ? 
ATOM   1290 O O   . GLN A 1 179 ? 15.541 -42.756 -20.594 1.000 81.689  0 183 GLN A O   1 ? 
ATOM   1291 C CB  . GLN A 1 179 ? 13.619 -45.036 -20.054 1.000 88.747  0 183 GLN A CB  1 ? 
ATOM   1292 C CG  . GLN A 1 179 ? 12.614 -46.169 -20.195 1.000 96.985  0 183 GLN A CG  1 ? 
ATOM   1293 C CD  . GLN A 1 179 ? 11.883 -46.465 -18.881 1.000 99.694  0 183 GLN A CD  1 ? 
ATOM   1294 O OE1 . GLN A 1 179 ? 12.470 -46.383 -17.798 1.000 97.762  0 183 GLN A OE1 1 ? 
ATOM   1295 N NE2 . GLN A 1 179 ? 10.601 -46.814 -18.976 1.000 97.199  0 183 GLN A NE2 1 ? 
ATOM   1296 N N   . LEU A 1 180 ? 16.941 -44.507 -20.462 1.000 65.126  0 184 LEU A N   1 ? 
ATOM   1297 C CA  . LEU A 1 180 ? 18.071 -43.694 -20.024 1.000 66.332  0 184 LEU A CA  1 ? 
ATOM   1298 C C   . LEU A 1 180 ? 18.673 -43.006 -21.244 1.000 74.009  0 184 LEU A C   1 ? 
ATOM   1299 O O   . LEU A 1 180 ? 19.099 -43.681 -22.189 1.000 76.304  0 184 LEU A O   1 ? 
ATOM   1300 C CB  . LEU A 1 180 ? 19.105 -44.562 -19.300 1.000 59.994  0 184 LEU A CB  1 ? 
ATOM   1301 C CG  . LEU A 1 180 ? 20.403 -43.932 -18.780 1.000 54.591  0 184 LEU A CG  1 ? 
ATOM   1302 C CD1 . LEU A 1 180 ? 20.135 -42.674 -17.959 1.000 49.414  0 184 LEU A CD1 1 ? 
ATOM   1303 C CD2 . LEU A 1 180 ? 21.257 -44.942 -17.987 1.000 54.528  0 184 LEU A CD2 1 ? 
ATOM   1304 N N   . LYS A 1 181 ? 18.696 -41.665 -21.230 1.000 74.730  0 185 LYS A N   1 ? 
ATOM   1305 C CA  . LYS A 1 181 ? 19.044 -40.860 -22.400 1.000 72.498  0 185 LYS A CA  1 ? 
ATOM   1306 C C   . LYS A 1 181 ? 20.259 -39.964 -22.178 1.000 67.153  0 185 LYS A C   1 ? 
ATOM   1307 O O   . LYS A 1 181 ? 20.556 -39.116 -23.033 1.000 57.736  0 185 LYS A O   1 ? 
ATOM   1308 C CB  . LYS A 1 181 ? 17.845 -40.008 -22.829 1.000 69.092  0 185 LYS A CB  1 ? 
ATOM   1309 C CG  . LYS A 1 181 ? 16.615 -40.816 -23.180 1.000 67.221  0 185 LYS A CG  1 ? 
ATOM   1310 C CD  . LYS A 1 181 ? 16.844 -41.555 -24.479 1.000 76.435  0 185 LYS A CD  1 ? 
ATOM   1311 C CE  . LYS A 1 181 ? 15.730 -42.546 -24.776 1.000 81.283  0 185 LYS A CE  1 ? 
ATOM   1312 N NZ  . LYS A 1 181 ? 16.306 -43.841 -25.246 1.000 81.818  0 185 LYS A NZ  1 ? 
ATOM   1313 N N   . ILE A 1 182 ? 20.959 -40.128 -21.057 1.000 67.148  0 186 ILE A N   1 ? 
ATOM   1314 C CA  . ILE A 1 182 ? 22.204 -39.417 -20.760 1.000 63.668  0 186 ILE A CA  1 ? 
ATOM   1315 C C   . ILE A 1 182 ? 23.205 -40.408 -20.170 1.000 64.776  0 186 ILE A C   1 ? 
ATOM   1316 O O   . ILE A 1 182 ? 22.834 -41.505 -19.741 1.000 51.954  0 186 ILE A O   1 ? 
ATOM   1317 C CB  . ILE A 1 182 ? 21.984 -38.239 -19.782 1.000 56.546  0 186 ILE A CB  1 ? 
ATOM   1318 C CG1 . ILE A 1 182 ? 21.560 -38.749 -18.403 1.000 58.865  0 186 ILE A CG1 1 ? 
ATOM   1319 C CG2 . ILE A 1 182 ? 20.942 -37.272 -20.319 1.000 57.931  0 186 ILE A CG2 1 ? 
ATOM   1320 C CD1 . ILE A 1 182 ? 21.317 -37.638 -17.359 1.000 49.259  0 186 ILE A CD1 1 ? 
ATOM   1321 N N   . PRO A 1 183 ? 24.493 -40.049 -20.180 1.000 76.128  0 187 PRO A N   1 ? 
ATOM   1322 C CA  . PRO A 1 183 ? 25.491 -40.866 -19.458 1.000 72.143  0 187 PRO A CA  1 ? 
ATOM   1323 C C   . PRO A 1 183 ? 25.338 -40.768 -17.939 1.000 60.289  0 187 PRO A C   1 ? 
ATOM   1324 O O   . PRO A 1 183 ? 24.981 -39.724 -17.387 1.000 53.522  0 187 PRO A O   1 ? 
ATOM   1325 C CB  . PRO A 1 183 ? 26.835 -40.277 -19.917 1.000 74.904  0 187 PRO A CB  1 ? 
ATOM   1326 C CG  . PRO A 1 183 ? 26.535 -39.550 -21.202 1.000 82.078  0 187 PRO A CG  1 ? 
ATOM   1327 C CD  . PRO A 1 183 ? 25.115 -39.071 -21.093 1.000 80.673  0 187 PRO A CD  1 ? 
ATOM   1328 N N   . ALA A 1 184 ? 25.633 -41.874 -17.252 1.000 59.152  0 188 ALA A N   1 ? 
ATOM   1329 C CA  . ALA A 1 184 ? 25.378 -41.959 -15.814 1.000 55.446  0 188 ALA A CA  1 ? 
ATOM   1330 C C   . ALA A 1 184 ? 26.522 -42.653 -15.089 1.000 63.876  0 188 ALA A C   1 ? 
ATOM   1331 O O   . ALA A 1 184 ? 26.895 -43.777 -15.445 1.000 63.489  0 188 ALA A O   1 ? 
ATOM   1332 C CB  . ALA A 1 184 ? 24.064 -42.699 -15.535 1.000 54.980  0 188 ALA A CB  1 ? 
ATOM   1333 N N   . ILE A 1 185 ? 27.048 -41.992 -14.051 1.000 68.169  0 189 ILE A N   1 ? 
ATOM   1334 C CA  . ILE A 1 185 ? 28.159 -42.492 -13.245 1.000 55.628  0 189 ILE A CA  1 ? 
ATOM   1335 C C   . ILE A 1 185 ? 27.623 -43.011 -11.915 1.000 55.757  0 189 ILE A C   1 ? 
ATOM   1336 O O   . ILE A 1 185 ? 27.123 -42.235 -11.090 1.000 62.273  0 189 ILE A O   1 ? 
ATOM   1337 C CB  . ILE A 1 185 ? 29.213 -41.412 -13.007 1.000 49.261  0 189 ILE A CB  1 ? 
ATOM   1338 C CG1 . ILE A 1 185 ? 30.090 -41.303 -14.226 1.000 39.936  0 189 ILE A CG1 1 ? 
ATOM   1339 C CG2 . ILE A 1 185 ? 30.073 -41.803 -11.785 1.000 59.647  0 189 ILE A CG2 1 ? 
ATOM   1340 C CD1 . ILE A 1 185 ? 30.646 -42.635 -14.628 1.000 40.063  0 189 ILE A CD1 1 ? 
ATOM   1341 N N   . ASN A 1 186 ? 27.771 -44.321 -11.687 1.000 44.895  0 190 ASN A N   1 ? 
ATOM   1342 C CA  . ASN A 1 186 ? 27.376 -44.946 -10.429 1.000 40.084  0 190 ASN A CA  1 ? 
ATOM   1343 C C   . ASN A 1 186 ? 28.395 -44.629 -9.339  1.000 41.518  0 190 ASN A C   1 ? 
ATOM   1344 O O   . ASN A 1 186 ? 29.349 -45.388 -9.123  1.000 50.306  0 190 ASN A O   1 ? 
ATOM   1345 C CB  . ASN A 1 186 ? 27.215 -46.462 -10.616 1.000 43.618  0 190 ASN A CB  1 ? 
ATOM   1346 C CG  . ASN A 1 186 ? 26.752 -47.193 -9.338  1.000 49.103  0 190 ASN A CG  1 ? 
ATOM   1347 O OD1 . ASN A 1 186 ? 26.507 -46.588 -8.284  1.000 48.345  0 190 ASN A OD1 1 ? 
ATOM   1348 N ND2 . ASN A 1 186 ? 26.645 -48.513 -9.439  1.000 50.340  0 190 ASN A ND2 1 ? 
ATOM   1349 N N   . VAL A 1 187 ? 28.199 -43.511 -8.640  1.000 38.447  0 191 VAL A N   1 ? 
ATOM   1350 C CA  . VAL A 1 187 ? 29.079 -43.207 -7.520  1.000 36.460  0 191 VAL A CA  1 ? 
ATOM   1351 C C   . VAL A 1 187 ? 28.850 -44.186 -6.379  1.000 38.305  0 191 VAL A C   1 ? 
ATOM   1352 O O   . VAL A 1 187 ? 29.806 -44.567 -5.700  1.000 38.910  0 191 VAL A O   1 ? 
ATOM   1353 C CB  . VAL A 1 187 ? 28.908 -41.746 -7.065  1.000 42.624  0 191 VAL A CB  1 ? 
ATOM   1354 C CG1 . VAL A 1 187 ? 29.297 -41.592 -5.604  1.000 49.161  0 191 VAL A CG1 1 ? 
ATOM   1355 C CG2 . VAL A 1 187 ? 29.748 -40.807 -7.941  1.000 38.994  0 191 VAL A CG2 1 ? 
ATOM   1356 N N   . ASN A 1 188 ? 27.605 -44.645 -6.163  1.000 41.623  0 192 ASN A N   1 ? 
ATOM   1357 C CA  . ASN A 1 188 ? 27.355 -45.558 -5.043  1.000 43.645  0 192 ASN A CA  1 ? 
ATOM   1358 C C   . ASN A 1 188 ? 28.318 -46.745 -5.033  1.000 53.080  0 192 ASN A C   1 ? 
ATOM   1359 O O   . ASN A 1 188 ? 28.714 -47.217 -3.958  1.000 37.965  0 192 ASN A O   1 ? 
ATOM   1360 C CB  . ASN A 1 188 ? 25.921 -46.095 -5.052  1.000 35.925  0 192 ASN A CB  1 ? 
ATOM   1361 C CG  . ASN A 1 188 ? 25.649 -47.053 -3.865  1.000 40.623  0 192 ASN A CG  1 ? 
ATOM   1362 O OD1 . ASN A 1 188 ? 25.687 -46.646 -2.691  1.000 35.986  0 192 ASN A OD1 1 ? 
ATOM   1363 N ND2 . ASN A 1 188 ? 25.372 -48.322 -4.172  1.000 31.188  0 192 ASN A ND2 1 ? 
ATOM   1364 N N   . ASN A 1 189 ? 28.730 -47.224 -6.206  1.000 55.815  0 193 ASN A N   1 ? 
ATOM   1365 C CA  . ASN A 1 189 ? 29.495 -48.458 -6.266  1.000 59.991  0 193 ASN A CA  1 ? 
ATOM   1366 C C   . ASN A 1 189 ? 30.995 -48.235 -6.375  1.000 57.725  0 193 ASN A C   1 ? 
ATOM   1367 O O   . ASN A 1 189 ? 31.733 -49.199 -6.608  1.000 53.875  0 193 ASN A O   1 ? 
ATOM   1368 C CB  . ASN A 1 189 ? 28.989 -49.338 -7.404  1.000 67.716  0 193 ASN A CB  1 ? 
ATOM   1369 C CG  . ASN A 1 189 ? 27.890 -50.282 -6.945  1.000 72.043  0 193 ASN A CG  1 ? 
ATOM   1370 O OD1 . ASN A 1 189 ? 26.724 -49.886 -6.813  1.000 76.472  0 193 ASN A OD1 1 ? 
ATOM   1371 N ND2 . ASN A 1 189 ? 28.261 -51.533 -6.672  1.000 63.958  0 193 ASN A ND2 1 ? 
ATOM   1372 N N   . ALA A 1 190 ? 31.465 -46.999 -6.197  1.000 52.462  0 194 ALA A N   1 ? 
ATOM   1373 C CA  . ALA A 1 190 ? 32.844 -46.795 -5.786  1.000 43.224  0 194 ALA A CA  1 ? 
ATOM   1374 C C   . ALA A 1 190 ? 33.050 -47.469 -4.441  1.000 50.198  0 194 ALA A C   1 ? 
ATOM   1375 O O   . ALA A 1 190 ? 32.285 -47.233 -3.500  1.000 55.296  0 194 ALA A O   1 ? 
ATOM   1376 C CB  . ALA A 1 190 ? 33.165 -45.308 -5.680  1.000 44.166  0 194 ALA A CB  1 ? 
ATOM   1377 N N   . VAL A 1 191 ? 34.059 -48.346 -4.368  1.000 45.337  0 195 VAL A N   1 ? 
ATOM   1378 C CA  . VAL A 1 191 ? 34.370 -49.043 -3.122  1.000 42.516  0 195 VAL A CA  1 ? 
ATOM   1379 C C   . VAL A 1 191 ? 34.447 -48.069 -1.958  1.000 37.368  0 195 VAL A C   1 ? 
ATOM   1380 O O   . VAL A 1 191 ? 34.049 -48.399 -0.837  1.000 41.379  0 195 VAL A O   1 ? 
ATOM   1381 C CB  . VAL A 1 191 ? 35.687 -49.830 -3.264  1.000 35.778  0 195 VAL A CB  1 ? 
ATOM   1382 C CG1 . VAL A 1 191 ? 35.907 -50.727 -2.050  1.000 37.789  0 195 VAL A CG1 1 ? 
ATOM   1383 C CG2 . VAL A 1 191 ? 35.674 -50.617 -4.544  1.000 29.969  0 195 VAL A CG2 1 ? 
ATOM   1384 N N   . THR A 1 192 ? 34.934 -46.851 -2.202  1.000 34.654  0 196 THR A N   1 ? 
ATOM   1385 C CA  . THR A 1 192 ? 35.073 -45.883 -1.130  1.000 34.820  0 196 THR A CA  1 ? 
ATOM   1386 C C   . THR A 1 192 ? 33.804 -45.101 -0.873  1.000 35.262  0 196 THR A C   1 ? 
ATOM   1387 O O   . THR A 1 192 ? 33.824 -44.200 -0.027  1.000 37.094  0 196 THR A O   1 ? 
ATOM   1388 C CB  . THR A 1 192 ? 36.235 -44.936 -1.411  1.000 39.436  0 196 THR A CB  1 ? 
ATOM   1389 O OG1 . THR A 1 192 ? 36.069 -44.323 -2.704  1.000 43.624  0 196 THR A OG1 1 ? 
ATOM   1390 C CG2 . THR A 1 192 ? 37.546 -45.720 -1.325  1.000 26.624  0 196 THR A CG2 1 ? 
ATOM   1391 N N   . LYS A 1 193 ? 32.717 -45.428 -1.575  1.000 33.454  0 197 LYS A N   1 ? 
ATOM   1392 C CA  . LYS A 1 193 ? 31.377 -45.003 -1.192  1.000 36.652  0 197 LYS A CA  1 ? 
ATOM   1393 C C   . LYS A 1 193 ? 30.641 -46.172 -0.539  1.000 41.042  0 197 LYS A C   1 ? 
ATOM   1394 O O   . LYS A 1 193 ? 30.375 -46.146 0.668   1.000 37.531  0 197 LYS A O   1 ? 
ATOM   1395 C CB  . LYS A 1 193 ? 30.598 -44.474 -2.407  1.000 33.557  0 197 LYS A CB  1 ? 
ATOM   1396 C CG  . LYS A 1 193 ? 29.355 -43.632 -2.074  1.000 39.207  0 197 LYS A CG  1 ? 
ATOM   1397 C CD  . LYS A 1 193 ? 28.162 -44.515 -1.719  1.000 44.387  0 197 LYS A CD  1 ? 
ATOM   1398 C CE  . LYS A 1 193 ? 27.043 -43.771 -1.000  1.000 41.181  0 197 LYS A CE  1 ? 
ATOM   1399 N NZ  . LYS A 1 193 ? 25.755 -44.566 -1.050  1.000 31.862  0 197 LYS A NZ  1 ? 
ATOM   1400 N N   . SER A 1 194 ? 30.321 -47.198 -1.339  1.000 43.682  0 198 SER A N   1 ? 
ATOM   1401 C CA  . SER A 1 194 ? 29.448 -48.282 -0.895  1.000 41.287  0 198 SER A CA  1 ? 
ATOM   1402 C C   . SER A 1 194 ? 29.974 -48.933 0.365   1.000 45.900  0 198 SER A C   1 ? 
ATOM   1403 O O   . SER A 1 194 ? 29.234 -49.132 1.340   1.000 46.277  0 198 SER A O   1 ? 
ATOM   1404 C CB  . SER A 1 194 ? 29.326 -49.340 -1.988  1.000 44.087  0 198 SER A CB  1 ? 
ATOM   1405 O OG  . SER A 1 194 ? 30.548 -50.031 -2.160  1.000 42.771  0 198 SER A OG  1 ? 
ATOM   1406 N N   . LYS A 1 195 ? 31.252 -49.288 0.361   1.000 35.699  0 199 LYS A N   1 ? 
ATOM   1407 C CA  . LYS A 1 195 ? 31.786 -50.085 1.444   1.000 36.039  0 199 LYS A CA  1 ? 
ATOM   1408 C C   . LYS A 1 195 ? 32.233 -49.236 2.600   1.000 31.646  0 199 LYS A C   1 ? 
ATOM   1409 O O   . LYS A 1 195 ? 32.905 -49.741 3.505   1.000 38.602  0 199 LYS A O   1 ? 
ATOM   1410 C CB  . LYS A 1 195 ? 32.908 -50.974 0.929   1.000 41.289  0 199 LYS A CB  1 ? 
ATOM   1411 C CG  . LYS A 1 195 ? 32.348 -52.101 0.077   1.000 46.724  0 199 LYS A CG  1 ? 
ATOM   1412 C CD  . LYS A 1 195 ? 33.136 -53.359 0.287   1.000 52.933  0 199 LYS A CD  1 ? 
ATOM   1413 C CE  . LYS A 1 195 ? 32.546 -54.225 1.365   1.000 49.974  0 199 LYS A CE  1 ? 
ATOM   1414 N NZ  . LYS A 1 195 ? 32.798 -55.633 0.960   1.000 54.101  0 199 LYS A NZ  1 ? 
ATOM   1415 N N   . PHE A 1 196 ? 31.821 -47.970 2.613   1.000 31.867  0 200 PHE A N   1 ? 
ATOM   1416 C CA  . PHE A 1 196 ? 32.248 -47.001 3.611   1.000 25.648  0 200 PHE A CA  1 ? 
ATOM   1417 C C   . PHE A 1 196 ? 31.078 -46.158 4.070   1.000 32.314  0 200 PHE A C   1 ? 
ATOM   1418 O O   . PHE A 1 196 ? 30.701 -46.201 5.245   1.000 36.602  0 200 PHE A O   1 ? 
ATOM   1419 C CB  . PHE A 1 196 ? 33.338 -46.103 3.046   1.000 24.964  0 200 PHE A CB  1 ? 
ATOM   1420 C CG  . PHE A 1 196 ? 34.668 -46.750 3.019   1.000 27.888  0 200 PHE A CG  1 ? 
ATOM   1421 C CD1 . PHE A 1 196 ? 35.495 -46.710 4.135   1.000 25.277  0 200 PHE A CD1 1 ? 
ATOM   1422 C CD2 . PHE A 1 196 ? 35.094 -47.437 1.894   1.000 26.651  0 200 PHE A CD2 1 ? 
ATOM   1423 C CE1 . PHE A 1 196 ? 36.746 -47.335 4.121   1.000 27.259  0 200 PHE A CE1 1 ? 
ATOM   1424 C CE2 . PHE A 1 196 ? 36.352 -48.060 1.865   1.000 32.156  0 200 PHE A CE2 1 ? 
ATOM   1425 C CZ  . PHE A 1 196 ? 37.174 -48.008 2.978   1.000 30.101  0 200 PHE A CZ  1 ? 
ATOM   1426 N N   . ASP A 1 197 ? 30.516 -45.376 3.149   1.000 29.911  0 201 ASP A N   1 ? 
ATOM   1427 C CA  . ASP A 1 197 ? 29.326 -44.592 3.443   1.000 29.996  0 201 ASP A CA  1 ? 
ATOM   1428 C C   . ASP A 1 197 ? 28.204 -45.498 3.939   1.000 26.532  0 201 ASP A C   1 ? 
ATOM   1429 O O   . ASP A 1 197 ? 27.792 -45.395 5.097   1.000 37.041  0 201 ASP A O   1 ? 
ATOM   1430 C CB  . ASP A 1 197 ? 28.899 -43.804 2.202   1.000 42.318  0 201 ASP A CB  1 ? 
ATOM   1431 C CG  . ASP A 1 197 ? 27.612 -43.022 2.407   1.000 40.152  0 201 ASP A CG  1 ? 
ATOM   1432 O OD1 . ASP A 1 197 ? 26.594 -43.625 2.791   1.000 45.308  0 201 ASP A OD1 1 ? 
ATOM   1433 O OD2 . ASP A 1 197 ? 27.604 -41.805 2.149   1.000 43.879  0 201 ASP A OD2 1 ? 
ATOM   1434 N N   . ASN A 1 198 ? 27.712 -46.397 3.084   1.000 30.448  0 202 ASN A N   1 ? 
ATOM   1435 C CA  . ASN A 1 198 ? 26.543 -47.187 3.454   1.000 39.660  0 202 ASN A CA  1 ? 
ATOM   1436 C C   . ASN A 1 198 ? 26.796 -47.976 4.738   1.000 45.653  0 202 ASN A C   1 ? 
ATOM   1437 O O   . ASN A 1 198 ? 25.893 -48.110 5.579   1.000 49.409  0 202 ASN A O   1 ? 
ATOM   1438 C CB  . ASN A 1 198 ? 26.128 -48.133 2.313   1.000 45.642  0 202 ASN A CB  1 ? 
ATOM   1439 C CG  . ASN A 1 198 ? 26.132 -47.462 0.921   1.000 52.933  0 202 ASN A CG  1 ? 
ATOM   1440 O OD1 . ASN A 1 198 ? 26.175 -46.241 0.796   1.000 54.991  0 202 ASN A OD1 1 ? 
ATOM   1441 N ND2 . ASN A 1 198 ? 26.045 -48.279 -0.125  1.000 54.054  0 202 ASN A ND2 1 ? 
ATOM   1442 N N   . LEU A 1 199 ? 28.029 -48.458 4.936   1.000 27.545  0 203 LEU A N   1 ? 
ATOM   1443 C CA  . LEU A 1 199 ? 28.314 -49.391 6.033   1.000 35.741  0 203 LEU A CA  1 ? 
ATOM   1444 C C   . LEU A 1 199 ? 28.719 -48.670 7.325   1.000 38.152  0 203 LEU A C   1 ? 
ATOM   1445 O O   . LEU A 1 199 ? 27.994 -48.726 8.324   1.000 34.815  0 203 LEU A O   1 ? 
ATOM   1446 C CB  . LEU A 1 199 ? 29.364 -50.406 5.567   1.000 28.996  0 203 LEU A CB  1 ? 
ATOM   1447 C CG  . LEU A 1 199 ? 30.022 -51.280 6.642   1.000 35.496  0 203 LEU A CG  1 ? 
ATOM   1448 C CD1 . LEU A 1 199 ? 29.095 -52.337 7.115   1.000 23.534  0 203 LEU A CD1 1 ? 
ATOM   1449 C CD2 . LEU A 1 199 ? 31.362 -51.904 6.174   1.000 34.165  0 203 LEU A CD2 1 ? 
ATOM   1450 N N   . TYR A 1 200 ? 29.877 -47.990 7.317   1.000 28.732  0 204 TYR A N   1 ? 
ATOM   1451 C CA  . TYR A 1 200 ? 30.381 -47.304 8.503   1.000 23.382  0 204 TYR A CA  1 ? 
ATOM   1452 C C   . TYR A 1 200 ? 29.558 -46.074 8.874   1.000 28.922  0 204 TYR A C   1 ? 
ATOM   1453 O O   . TYR A 1 200 ? 29.473 -45.722 10.060  1.000 34.325  0 204 TYR A O   1 ? 
ATOM   1454 C CB  . TYR A 1 200 ? 31.845 -46.891 8.292   1.000 25.219  0 204 TYR A CB  1 ? 
ATOM   1455 C CG  . TYR A 1 200 ? 32.746 -48.061 7.974   1.000 25.364  0 204 TYR A CG  1 ? 
ATOM   1456 C CD1 . TYR A 1 200 ? 32.734 -49.207 8.777   1.000 22.176  0 204 TYR A CD1 1 ? 
ATOM   1457 C CD2 . TYR A 1 200 ? 33.582 -48.044 6.861   1.000 28.393  0 204 TYR A CD2 1 ? 
ATOM   1458 C CE1 . TYR A 1 200 ? 33.536 -50.290 8.498   1.000 21.926  0 204 TYR A CE1 1 ? 
ATOM   1459 C CE2 . TYR A 1 200 ? 34.407 -49.143 6.567   1.000 30.706  0 204 TYR A CE2 1 ? 
ATOM   1460 C CZ  . TYR A 1 200 ? 34.379 -50.257 7.392   1.000 33.196  0 204 TYR A CZ  1 ? 
ATOM   1461 O OH  . TYR A 1 200 ? 35.169 -51.353 7.106   1.000 30.340  0 204 TYR A OH  1 ? 
ATOM   1462 N N   . GLY A 1 201 ? 28.971 -45.386 7.894   1.000 28.224  0 205 GLY A N   1 ? 
ATOM   1463 C CA  . GLY A 1 201 ? 28.123 -44.252 8.220   1.000 25.245  0 205 GLY A CA  1 ? 
ATOM   1464 C C   . GLY A 1 201 ? 26.836 -44.663 8.919   1.000 36.070  0 205 GLY A C   1 ? 
ATOM   1465 O O   . GLY A 1 201 ? 26.422 -44.039 9.905   1.000 32.988  0 205 GLY A O   1 ? 
ATOM   1466 N N   . CYS A 1 202 ? 26.166 -45.700 8.403   1.000 25.693  0 206 CYS A N   1 ? 
ATOM   1467 C CA  . CYS A 1 202 ? 24.932 -46.154 9.038   1.000 31.435  0 206 CYS A CA  1 ? 
ATOM   1468 C C   . CYS A 1 202 ? 25.227 -46.829 10.359  1.000 32.496  0 206 CYS A C   1 ? 
ATOM   1469 O O   . CYS A 1 202 ? 24.408 -46.765 11.285  1.000 34.025  0 206 CYS A O   1 ? 
ATOM   1470 C CB  . CYS A 1 202 ? 24.157 -47.109 8.128   1.000 32.851  0 206 CYS A CB  1 ? 
ATOM   1471 S SG  . CYS A 1 202 ? 23.414 -46.299 6.737   1.000 38.270  0 206 CYS A SG  1 ? 
ATOM   1472 N N   . ARG A 1 203 ? 26.405 -47.452 10.472  1.000 24.474  0 207 ARG A N   1 ? 
ATOM   1473 C CA  . ARG A 1 203 ? 26.842 -47.955 11.770  1.000 27.206  0 207 ARG A CA  1 ? 
ATOM   1474 C C   . ARG A 1 203 ? 26.791 -46.868 12.839  1.000 32.104  0 207 ARG A C   1 ? 
ATOM   1475 O O   . ARG A 1 203 ? 26.589 -47.167 14.024  1.000 26.290  0 207 ARG A O   1 ? 
ATOM   1476 C CB  . ARG A 1 203 ? 28.255 -48.532 11.677  1.000 23.071  0 207 ARG A CB  1 ? 
ATOM   1477 C CG  . ARG A 1 203 ? 28.662 -49.245 12.940  1.000 22.484  0 207 ARG A CG  1 ? 
ATOM   1478 C CD  . ARG A 1 203 ? 29.919 -50.028 12.756  1.000 27.456  0 207 ARG A CD  1 ? 
ATOM   1479 N NE  . ARG A 1 203 ? 31.064 -49.140 12.653  1.000 24.132  0 207 ARG A NE  1 ? 
ATOM   1480 C CZ  . ARG A 1 203 ? 32.300 -49.547 12.398  1.000 28.335  0 207 ARG A CZ  1 ? 
ATOM   1481 N NH1 . ARG A 1 203 ? 32.551 -50.835 12.216  1.000 27.488  0 207 ARG A NH1 1 ? 
ATOM   1482 N NH2 . ARG A 1 203 ? 33.279 -48.662 12.306  1.000 21.047  0 207 ARG A NH2 1 ? 
ATOM   1483 N N   . GLU A 1 204 ? 26.950 -45.602 12.446  1.000 33.488  0 208 GLU A N   1 ? 
ATOM   1484 C CA  . GLU A 1 204 ? 26.949 -44.526 13.425  1.000 36.102  0 208 GLU A CA  1 ? 
ATOM   1485 C C   . GLU A 1 204 ? 25.642 -43.737 13.472  1.000 35.554  0 208 GLU A C   1 ? 
ATOM   1486 O O   . GLU A 1 204 ? 25.191 -43.372 14.562  1.000 37.220  0 208 GLU A O   1 ? 
ATOM   1487 C CB  . GLU A 1 204 ? 28.142 -43.599 13.177  1.000 23.966  0 208 GLU A CB  1 ? 
ATOM   1488 C CG  . GLU A 1 204 ? 29.428 -44.259 13.637  1.000 26.448  0 208 GLU A CG  1 ? 
ATOM   1489 C CD  . GLU A 1 204 ? 30.678 -43.403 13.474  1.000 31.585  0 208 GLU A CD  1 ? 
ATOM   1490 O OE1 . GLU A 1 204 ? 31.720 -44.004 13.151  1.000 37.283  0 208 GLU A OE1 1 ? 
ATOM   1491 O OE2 . GLU A 1 204 ? 30.641 -42.158 13.681  1.000 25.240  0 208 GLU A OE2 1 ? 
ATOM   1492 N N   . SER A 1 205 ? 24.985 -43.497 12.346  1.000 30.230  0 209 SER A N   1 ? 
ATOM   1493 C CA  . SER A 1 205 ? 23.845 -42.582 12.369  1.000 29.135  0 209 SER A CA  1 ? 
ATOM   1494 C C   . SER A 1 205 ? 22.498 -43.261 12.624  1.000 33.959  0 209 SER A C   1 ? 
ATOM   1495 O O   . SER A 1 205 ? 21.538 -42.567 12.990  1.000 28.338  0 209 SER A O   1 ? 
ATOM   1496 C CB  . SER A 1 205 ? 23.782 -41.777 11.066  1.000 27.643  0 209 SER A CB  1 ? 
ATOM   1497 O OG  . SER A 1 205 ? 23.887 -42.612 9.936   1.000 32.583  0 209 SER A OG  1 ? 
ATOM   1498 N N   . LEU A 1 206 ? 22.387 -44.586 12.463  1.000 27.124  0 210 LEU A N   1 ? 
ATOM   1499 C CA  . LEU A 1 206 ? 21.164 -45.250 12.915  1.000 27.619  0 210 LEU A CA  1 ? 
ATOM   1500 C C   . LEU A 1 206 ? 21.013 -45.106 14.422  1.000 33.767  0 210 LEU A C   1 ? 
ATOM   1501 O O   . LEU A 1 206 ? 19.956 -44.689 14.917  1.000 35.407  0 210 LEU A O   1 ? 
ATOM   1502 C CB  . LEU A 1 206 ? 21.147 -46.725 12.511  1.000 27.240  0 210 LEU A CB  1 ? 
ATOM   1503 C CG  . LEU A 1 206 ? 20.047 -47.545 13.199  1.000 27.619  0 210 LEU A CG  1 ? 
ATOM   1504 C CD1 . LEU A 1 206 ? 18.668 -47.284 12.566  1.000 28.793  0 210 LEU A CD1 1 ? 
ATOM   1505 C CD2 . LEU A 1 206 ? 20.364 -49.043 13.228  1.000 27.006  0 210 LEU A CD2 1 ? 
ATOM   1506 N N   . LEU A 1 207 ? 22.076 -45.425 15.170  1.000 30.177  0 211 LEU A N   1 ? 
ATOM   1507 C CA  . LEU A 1 207 ? 22.045 -45.229 16.615  1.000 29.554  0 211 LEU A CA  1 ? 
ATOM   1508 C C   . LEU A 1 207 ? 21.634 -43.808 16.953  1.000 30.835  0 211 LEU A C   1 ? 
ATOM   1509 O O   . LEU A 1 207 ? 20.710 -43.581 17.746  1.000 37.723  0 211 LEU A O   1 ? 
ATOM   1510 C CB  . LEU A 1 207 ? 23.408 -45.541 17.221  1.000 37.120  0 211 LEU A CB  1 ? 
ATOM   1511 C CG  . LEU A 1 207 ? 23.697 -47.026 17.229  1.000 44.813  0 211 LEU A CG  1 ? 
ATOM   1512 C CD1 . LEU A 1 207 ? 25.084 -47.302 17.791  1.000 45.929  0 211 LEU A CD1 1 ? 
ATOM   1513 C CD2 . LEU A 1 207 ? 22.619 -47.708 18.019  1.000 46.221  0 211 LEU A CD2 1 ? 
ATOM   1514 N N   . ASP A 1 208 ? 22.310 -42.843 16.327  1.000 29.543  0 212 ASP A N   1 ? 
ATOM   1515 C CA  . ASP A 1 208 ? 21.997 -41.423 16.455  1.000 27.848  0 212 ASP A CA  1 ? 
ATOM   1516 C C   . ASP A 1 208 ? 20.497 -41.140 16.261  1.000 37.436  0 212 ASP A C   1 ? 
ATOM   1517 O O   . ASP A 1 208 ? 19.844 -40.552 17.135  1.000 29.751  0 212 ASP A O   1 ? 
ATOM   1518 C CB  . ASP A 1 208 ? 22.854 -40.662 15.436  1.000 34.199  0 212 ASP A CB  1 ? 
ATOM   1519 C CG  . ASP A 1 208 ? 23.130 -39.218 15.837  1.000 45.305  0 212 ASP A CG  1 ? 
ATOM   1520 O OD1 . ASP A 1 208 ? 22.794 -38.801 16.974  1.000 47.095  0 212 ASP A OD1 1 ? 
ATOM   1521 O OD2 . ASP A 1 208 ? 23.694 -38.498 14.989  1.000 48.322  0 212 ASP A OD2 1 ? 
ATOM   1522 N N   . GLY A 1 209 ? 19.941 -41.551 15.113  1.000 29.525  0 213 GLY A N   1 ? 
ATOM   1523 C CA  . GLY A 1 209 ? 18.527 -41.317 14.852  1.000 30.785  0 213 GLY A CA  1 ? 
ATOM   1524 C C   . GLY A 1 209 ? 17.611 -41.900 15.919  1.000 36.768  0 213 GLY A C   1 ? 
ATOM   1525 O O   . GLY A 1 209 ? 16.726 -41.212 16.436  1.000 37.073  0 213 GLY A O   1 ? 
ATOM   1526 N N   . LEU A 1 210 ? 17.807 -43.183 16.257  1.000 31.996  0 214 LEU A N   1 ? 
ATOM   1527 C CA  . LEU A 1 210 ? 16.978 -43.816 17.277  1.000 30.693  0 214 LEU A CA  1 ? 
ATOM   1528 C C   . LEU A 1 210 ? 17.077 -43.061 18.587  1.000 35.575  0 214 LEU A C   1 ? 
ATOM   1529 O O   . LEU A 1 210 ? 16.052 -42.798 19.243  1.000 33.922  0 214 LEU A O   1 ? 
ATOM   1530 C CB  . LEU A 1 210 ? 17.390 -45.274 17.488  1.000 29.798  0 214 LEU A CB  1 ? 
ATOM   1531 C CG  . LEU A 1 210 ? 17.059 -46.297 16.409  1.000 35.562  0 214 LEU A CG  1 ? 
ATOM   1532 C CD1 . LEU A 1 210 ? 17.786 -47.583 16.724  1.000 32.793  0 214 LEU A CD1 1 ? 
ATOM   1533 C CD2 . LEU A 1 210 ? 15.538 -46.533 16.267  1.000 32.020  0 214 LEU A CD2 1 ? 
ATOM   1534 N N   . LYS A 1 211 ? 18.307 -42.678 18.961  1.000 29.919  0 215 LYS A N   1 ? 
ATOM   1535 C CA  . LYS A 1 211 ? 18.554 -42.039 20.248  1.000 34.407  0 215 LYS A CA  1 ? 
ATOM   1536 C C   . LYS A 1 211 ? 17.882 -40.677 20.333  1.000 36.381  0 215 LYS A C   1 ? 
ATOM   1537 O O   . LYS A 1 211 ? 17.161 -40.389 21.294  1.000 37.628  0 215 LYS A O   1 ? 
ATOM   1538 C CB  . LYS A 1 211 ? 20.055 -41.908 20.484  1.000 31.559  0 215 LYS A CB  1 ? 
ATOM   1539 C CG  . LYS A 1 211 ? 20.710 -43.206 20.867  1.000 37.068  0 215 LYS A CG  1 ? 
ATOM   1540 C CD  . LYS A 1 211 ? 20.869 -43.310 22.377  1.000 48.422  0 215 LYS A CD  1 ? 
ATOM   1541 C CE  . LYS A 1 211 ? 20.922 -44.775 22.828  1.000 49.416  0 215 LYS A CE  1 ? 
ATOM   1542 N NZ  . LYS A 1 211 ? 20.117 -44.969 24.075  1.000 48.743  0 215 LYS A NZ  1 ? 
ATOM   1543 N N   . ARG A 1 212 ? 18.107 -39.823 19.337  1.000 34.565  0 216 ARG A N   1 ? 
ATOM   1544 C CA  . ARG A 1 212 ? 17.528 -38.489 19.394  1.000 36.228  0 216 ARG A CA  1 ? 
ATOM   1545 C C   . ARG A 1 212 ? 16.013 -38.548 19.389  1.000 37.973  0 216 ARG A C   1 ? 
ATOM   1546 O O   . ARG A 1 212 ? 15.353 -37.688 19.985  1.000 36.465  0 216 ARG A O   1 ? 
ATOM   1547 C CB  . ARG A 1 212 ? 18.041 -37.646 18.224  1.000 36.289  0 216 ARG A CB  1 ? 
ATOM   1548 C CG  . ARG A 1 212 ? 19.557 -37.518 18.205  1.000 36.644  0 216 ARG A CG  1 ? 
ATOM   1549 C CD  . ARG A 1 212 ? 20.020 -36.339 17.394  1.000 32.601  0 216 ARG A CD  1 ? 
ATOM   1550 N NE  . ARG A 1 212 ? 21.354 -36.535 16.820  1.000 45.303  0 216 ARG A NE  1 ? 
ATOM   1551 C CZ  . ARG A 1 212 ? 22.164 -35.532 16.473  1.000 48.064  0 216 ARG A CZ  1 ? 
ATOM   1552 N NH1 . ARG A 1 212 ? 21.759 -34.282 16.672  1.000 34.941  0 216 ARG A NH1 1 ? 
ATOM   1553 N NH2 . ARG A 1 212 ? 23.376 -35.771 15.945  1.000 43.326  0 216 ARG A NH2 1 ? 
ATOM   1554 N N   . ALA A 1 213 ? 15.448 -39.568 18.745  1.000 33.857  0 217 ALA A N   1 ? 
ATOM   1555 C CA  . ALA A 1 213 ? 14.013 -39.607 18.535  1.000 35.217  0 217 ALA A CA  1 ? 
ATOM   1556 C C   . ALA A 1 213 ? 13.289 -40.170 19.747  1.000 38.618  0 217 ALA A C   1 ? 
ATOM   1557 O O   . ALA A 1 213 ? 12.223 -39.674 20.110  1.000 36.910  0 217 ALA A O   1 ? 
ATOM   1558 C CB  . ALA A 1 213 ? 13.697 -40.420 17.278  1.000 35.199  0 217 ALA A CB  1 ? 
ATOM   1559 N N   . THR A 1 214 ? 13.860 -41.188 20.399  1.000 32.993  0 218 THR A N   1 ? 
ATOM   1560 C CA  . THR A 1 214 ? 13.171 -41.925 21.454  1.000 26.882  0 218 THR A CA  1 ? 
ATOM   1561 C C   . THR A 1 214 ? 13.967 -42.086 22.734  1.000 30.201  0 218 THR A C   1 ? 
ATOM   1562 O O   . THR A 1 214 ? 13.363 -42.383 23.774  1.000 35.712  0 218 THR A O   1 ? 
ATOM   1563 C CB  . THR A 1 214 ? 12.792 -43.337 20.978  1.000 29.582  0 218 THR A CB  1 ? 
ATOM   1564 O OG1 . THR A 1 214 ? 13.959 -44.172 21.025  1.000 39.344  0 218 THR A OG1 1 ? 
ATOM   1565 C CG2 . THR A 1 214 ? 12.211 -43.328 19.542  1.000 26.661  0 218 THR A CG2 1 ? 
ATOM   1566 N N   . ASP A 1 215 ? 15.292 -41.970 22.694  1.000 30.214  0 219 ASP A N   1 ? 
ATOM   1567 C CA  . ASP A 1 215 ? 16.129 -42.225 23.865  1.000 32.675  0 219 ASP A CA  1 ? 
ATOM   1568 C C   . ASP A 1 215 ? 15.948 -43.641 24.414  1.000 32.330  0 219 ASP A C   1 ? 
ATOM   1569 O O   . ASP A 1 215 ? 16.117 -43.885 25.610  1.000 39.489  0 219 ASP A O   1 ? 
ATOM   1570 C CB  . ASP A 1 215 ? 15.861 -41.182 24.949  1.000 31.177  0 219 ASP A CB  1 ? 
ATOM   1571 C CG  . ASP A 1 215 ? 16.203 -39.789 24.482  1.000 48.937  0 219 ASP A CG  1 ? 
ATOM   1572 O OD1 . ASP A 1 215 ? 17.415 -39.497 24.337  1.000 52.975  0 219 ASP A OD1 1 ? 
ATOM   1573 O OD2 . ASP A 1 215 ? 15.263 -39.001 24.228  1.000 59.899  0 219 ASP A OD2 1 ? 
ATOM   1574 N N   . VAL A 1 216 ? 15.607 -44.591 23.555  1.000 32.193  0 220 VAL A N   1 ? 
ATOM   1575 C CA  . VAL A 1 216 ? 15.364 -45.952 24.011  1.000 32.062  0 220 VAL A CA  1 ? 
ATOM   1576 C C   . VAL A 1 216 ? 16.692 -46.641 24.300  1.000 28.493  0 220 VAL A C   1 ? 
ATOM   1577 O O   . VAL A 1 216 ? 17.674 -46.467 23.569  1.000 36.783  0 220 VAL A O   1 ? 
ATOM   1578 C CB  . VAL A 1 216 ? 14.524 -46.732 22.980  1.000 27.259  0 220 VAL A CB  1 ? 
ATOM   1579 C CG1 . VAL A 1 216 ? 15.355 -47.147 21.758  1.000 24.914  0 220 VAL A CG1 1 ? 
ATOM   1580 C CG2 . VAL A 1 216 ? 13.914 -47.933 23.621  1.000 25.319  0 220 VAL A CG2 1 ? 
ATOM   1581 N N   . MET A 1 217 ? 16.732 -47.416 25.382  1.000 25.248  0 221 MET A N   1 ? 
ATOM   1582 C CA  . MET A 1 217 ? 17.884 -48.277 25.635  1.000 26.703  0 221 MET A CA  1 ? 
ATOM   1583 C C   . MET A 1 217 ? 17.962 -49.352 24.565  1.000 29.888  0 221 MET A C   1 ? 
ATOM   1584 O O   . MET A 1 217 ? 16.947 -49.970 24.221  1.000 33.588  0 221 MET A O   1 ? 
ATOM   1585 C CB  . MET A 1 217 ? 17.788 -48.932 27.013  1.000 32.788  0 221 MET A CB  1 ? 
ATOM   1586 C CG  . MET A 1 217 ? 19.042 -49.687 27.395  1.000 43.350  0 221 MET A CG  1 ? 
ATOM   1587 S SD  . MET A 1 217 ? 20.140 -48.640 28.350  1.000 55.907  0 221 MET A SD  1 ? 
ATOM   1588 C CE  . MET A 1 217 ? 21.305 -49.847 28.984  1.000 62.376  0 221 MET A CE  1 ? 
ATOM   1589 N N   . ILE A 1 218 ? 19.164 -49.562 24.033  1.000 34.820  0 222 ILE A N   1 ? 
ATOM   1590 C CA  . ILE A 1 218 ? 19.387 -50.583 23.016  1.000 20.371  0 222 ILE A CA  1 ? 
ATOM   1591 C C   . ILE A 1 218 ? 19.741 -51.915 23.659  1.000 30.011  0 222 ILE A C   1 ? 
ATOM   1592 O O   . ILE A 1 218 ? 19.260 -52.964 23.226  1.000 30.996  0 222 ILE A O   1 ? 
ATOM   1593 C CB  . ILE A 1 218 ? 20.488 -50.118 22.041  1.000 20.279  0 222 ILE A CB  1 ? 
ATOM   1594 C CG1 . ILE A 1 218 ? 20.083 -48.827 21.347  1.000 20.487  0 222 ILE A CG1 1 ? 
ATOM   1595 C CG2 . ILE A 1 218 ? 20.835 -51.213 21.025  1.000 20.060  0 222 ILE A CG2 1 ? 
ATOM   1596 C CD1 . ILE A 1 218 ? 18.695 -48.867 20.747  1.000 20.571  0 222 ILE A CD1 1 ? 
ATOM   1597 N N   . ALA A 1 219 ? 20.544 -51.877 24.727  1.000 25.864  0 223 ALA A N   1 ? 
ATOM   1598 C CA  . ALA A 1 219 ? 20.971 -53.101 25.394  1.000 33.230  0 223 ALA A CA  1 ? 
ATOM   1599 C C   . ALA A 1 219 ? 19.764 -53.922 25.840  1.000 36.525  0 223 ALA A C   1 ? 
ATOM   1600 O O   . ALA A 1 219 ? 18.808 -53.396 26.423  1.000 38.618  0 223 ALA A O   1 ? 
ATOM   1601 C CB  . ALA A 1 219 ? 21.868 -52.768 26.585  1.000 20.452  0 223 ALA A CB  1 ? 
ATOM   1602 N N   . GLY A 1 220 ? 19.796 -55.216 25.536  1.000 32.296  0 224 GLY A N   1 ? 
ATOM   1603 C CA  . GLY A 1 220 ? 18.706 -56.099 25.890  1.000 29.996  0 224 GLY A CA  1 ? 
ATOM   1604 C C   . GLY A 1 220 ? 17.528 -56.104 24.944  1.000 26.966  0 224 GLY A C   1 ? 
ATOM   1605 O O   . GLY A 1 220 ? 16.670 -56.988 25.061  1.000 31.227  0 224 GLY A O   1 ? 
ATOM   1606 N N   . LYS A 1 221 ? 17.438 -55.155 24.017  1.000 29.222  0 225 LYS A N   1 ? 
ATOM   1607 C CA  . LYS A 1 221 ? 16.297 -55.131 23.112  1.000 25.972  0 225 LYS A CA  1 ? 
ATOM   1608 C C   . LYS A 1 221 ? 16.510 -56.097 21.957  1.000 30.069  0 225 LYS A C   1 ? 
ATOM   1609 O O   . LYS A 1 221 ? 17.647 -56.344 21.525  1.000 34.796  0 225 LYS A O   1 ? 
ATOM   1610 C CB  . LYS A 1 221 ? 16.064 -53.723 22.557  1.000 27.103  0 225 LYS A CB  1 ? 
ATOM   1611 C CG  . LYS A 1 221 ? 15.667 -52.691 23.593  1.000 29.538  0 225 LYS A CG  1 ? 
ATOM   1612 C CD  . LYS A 1 221 ? 14.243 -52.908 24.155  1.000 23.890  0 225 LYS A CD  1 ? 
ATOM   1613 C CE  . LYS A 1 221 ? 13.773 -51.659 24.870  1.000 26.069  0 225 LYS A CE  1 ? 
ATOM   1614 N NZ  . LYS A 1 221 ? 14.919 -51.057 25.673  1.000 23.595  0 225 LYS A NZ  1 ? 
ATOM   1615 N N   . VAL A 1 222 ? 15.404 -56.646 21.458  1.000 23.521  0 226 VAL A N   1 ? 
ATOM   1616 C CA  . VAL A 1 222 ? 15.413 -57.438 20.231  1.000 20.950  0 226 VAL A CA  1 ? 
ATOM   1617 C C   . VAL A 1 222 ? 15.131 -56.493 19.080  1.000 26.135  0 226 VAL A C   1 ? 
ATOM   1618 O O   . VAL A 1 222 ? 14.091 -55.829 19.039  1.000 34.407  0 226 VAL A O   1 ? 
ATOM   1619 C CB  . VAL A 1 222 ? 14.389 -58.583 20.264  1.000 21.426  0 226 VAL A CB  1 ? 
ATOM   1620 C CG1 . VAL A 1 222 ? 14.382 -59.283 18.931  1.000 26.253  0 226 VAL A CG1 1 ? 
ATOM   1621 C CG2 . VAL A 1 222 ? 14.704 -59.568 21.373  1.000 21.645  0 226 VAL A CG2 1 ? 
ATOM   1622 N N   . ALA A 1 223 ? 16.069 -56.428 18.158  1.000 21.600  0 227 ALA A N   1 ? 
ATOM   1623 C CA  . ALA A 1 223 ? 16.043 -55.509 17.039  1.000 22.376  0 227 ALA A CA  1 ? 
ATOM   1624 C C   . ALA A 1 223 ? 16.053 -56.335 15.767  1.000 27.016  0 227 ALA A C   1 ? 
ATOM   1625 O O   . ALA A 1 223 ? 16.835 -57.279 15.644  1.000 39.152  0 227 ALA A O   1 ? 
ATOM   1626 C CB  . ALA A 1 223 ? 17.259 -54.586 17.086  1.000 20.216  0 227 ALA A CB  1 ? 
ATOM   1627 N N   . LEU A 1 224 ? 15.210 -55.986 14.821  1.000 24.150  0 228 LEU A N   1 ? 
ATOM   1628 C CA  . LEU A 1 224 ? 15.174 -56.703 13.559  1.000 25.411  0 228 LEU A CA  1 ? 
ATOM   1629 C C   . LEU A 1 224 ? 15.606 -55.769 12.444  1.000 28.440  0 228 LEU A C   1 ? 
ATOM   1630 O O   . LEU A 1 224 ? 14.985 -54.720 12.235  1.000 25.511  0 228 LEU A O   1 ? 
ATOM   1631 C CB  . LEU A 1 224 ? 13.780 -57.253 13.295  1.000 22.497  0 228 LEU A CB  1 ? 
ATOM   1632 C CG  . LEU A 1 224 ? 13.555 -57.915 11.955  1.000 23.355  0 228 LEU A CG  1 ? 
ATOM   1633 C CD1 . LEU A 1 224 ? 14.434 -59.128 11.802  1.000 21.453  0 228 LEU A CD1 1 ? 
ATOM   1634 C CD2 . LEU A 1 224 ? 12.106 -58.306 11.908  1.000 23.287  0 228 LEU A CD2 1 ? 
ATOM   1635 N N   . ILE A 1 225 ? 16.673 -56.147 11.747  1.000 26.090  0 229 ILE A N   1 ? 
ATOM   1636 C CA  . ILE A 1 225 ? 17.105 -55.488 10.519  1.000 25.156  0 229 ILE A CA  1 ? 
ATOM   1637 C C   . ILE A 1 225 ? 16.541 -56.264 9.340   1.000 24.182  0 229 ILE A C   1 ? 
ATOM   1638 O O   . ILE A 1 225 ? 16.915 -57.425 9.130   1.000 29.417  0 229 ILE A O   1 ? 
ATOM   1639 C CB  . ILE A 1 225 ? 18.639 -55.427 10.416  1.000 32.359  0 229 ILE A CB  1 ? 
ATOM   1640 C CG1 . ILE A 1 225 ? 19.286 -55.026 11.755  1.000 32.820  0 229 ILE A CG1 1 ? 
ATOM   1641 C CG2 . ILE A 1 225 ? 19.054 -54.527 9.258   1.000 20.521  0 229 ILE A CG2 1 ? 
ATOM   1642 C CD1 . ILE A 1 225 ? 18.875 -53.661 12.247  1.000 30.748  0 229 ILE A CD1 1 ? 
ATOM   1643 N N   . LEU A 1 226 ? 15.662 -55.630 8.558   1.000 23.953  0 230 LEU A N   1 ? 
ATOM   1644 C CA  . LEU A 1 226 ? 15.219 -56.187 7.274   1.000 21.489  0 230 LEU A CA  1 ? 
ATOM   1645 C C   . LEU A 1 226 ? 16.209 -55.739 6.208   1.000 31.801  0 230 LEU A C   1 ? 
ATOM   1646 O O   . LEU A 1 226 ? 16.293 -54.549 5.887   1.000 21.524  0 230 LEU A O   1 ? 
ATOM   1647 C CB  . LEU A 1 226 ? 13.808 -55.742 6.906   1.000 25.027  0 230 LEU A CB  1 ? 
ATOM   1648 C CG  . LEU A 1 226 ? 12.752 -55.786 8.005   1.000 29.646  0 230 LEU A CG  1 ? 
ATOM   1649 C CD1 . LEU A 1 226 ? 11.362 -55.570 7.424   1.000 26.758  0 230 LEU A CD1 1 ? 
ATOM   1650 C CD2 . LEU A 1 226 ? 12.824 -57.135 8.635   1.000 39.589  0 230 LEU A CD2 1 ? 
ATOM   1651 N N   . GLY A 1 227 ? 16.966 -56.689 5.671   1.000 25.979  0 231 GLY A N   1 ? 
ATOM   1652 C CA  . GLY A 1 227 ? 18.005 -56.361 4.725   1.000 23.405  0 231 GLY A CA  1 ? 
ATOM   1653 C C   . GLY A 1 227 ? 19.396 -56.396 5.330   1.000 28.048  0 231 GLY A C   1 ? 
ATOM   1654 O O   . GLY A 1 227 ? 19.642 -55.770 6.365   1.000 25.798  0 231 GLY A O   1 ? 
ATOM   1655 N N   . TYR A 1 228 ? 20.314 -57.114 4.680   1.000 21.171  0 232 TYR A N   1 ? 
ATOM   1656 C CA  . TYR A 1 228 ? 21.711 -57.241 5.100   1.000 23.453  0 232 TYR A CA  1 ? 
ATOM   1657 C C   . TYR A 1 228 ? 22.633 -56.913 3.936   1.000 25.124  0 232 TYR A C   1 ? 
ATOM   1658 O O   . TYR A 1 228 ? 23.577 -57.639 3.635   1.000 26.732  0 232 TYR A O   1 ? 
ATOM   1659 C CB  . TYR A 1 228 ? 22.016 -58.643 5.653   1.000 27.135  0 232 TYR A CB  1 ? 
ATOM   1660 C CG  . TYR A 1 228 ? 23.190 -58.689 6.618   1.000 26.401  0 232 TYR A CG  1 ? 
ATOM   1661 C CD1 . TYR A 1 228 ? 23.169 -57.969 7.817   1.000 22.411  0 232 TYR A CD1 1 ? 
ATOM   1662 C CD2 . TYR A 1 228 ? 24.317 -59.447 6.330   1.000 20.776  0 232 TYR A CD2 1 ? 
ATOM   1663 C CE1 . TYR A 1 228 ? 24.253 -58.003 8.701   1.000 22.074  0 232 TYR A CE1 1 ? 
ATOM   1664 C CE2 . TYR A 1 228 ? 25.397 -59.494 7.184   1.000 26.643  0 232 TYR A CE2 1 ? 
ATOM   1665 C CZ  . TYR A 1 228 ? 25.373 -58.778 8.370   1.000 33.975  0 232 TYR A CZ  1 ? 
ATOM   1666 O OH  . TYR A 1 228 ? 26.464 -58.854 9.210   1.000 31.967  0 232 TYR A OH  1 ? 
ATOM   1667 N N   . GLY A 1 229 ? 22.353 -55.809 3.241   1.000 34.130  0 233 GLY A N   1 ? 
ATOM   1668 C CA  . GLY A 1 229 ? 23.330 -55.198 2.362   1.000 21.676  0 233 GLY A CA  1 ? 
ATOM   1669 C C   . GLY A 1 229 ? 24.269 -54.318 3.166   1.000 26.248  0 233 GLY A C   1 ? 
ATOM   1670 O O   . GLY A 1 229 ? 24.437 -54.495 4.379   1.000 24.682  0 233 GLY A O   1 ? 
ATOM   1671 N N   . ASP A 1 230 ? 24.861 -53.319 2.511   1.000 24.053  0 234 ASP A N   1 ? 
ATOM   1672 C CA  . ASP A 1 230 ? 25.850 -52.524 3.234   1.000 26.598  0 234 ASP A CA  1 ? 
ATOM   1673 C C   . ASP A 1 230 ? 25.201 -51.672 4.319   1.000 32.751  0 234 ASP A C   1 ? 
ATOM   1674 O O   . ASP A 1 230 ? 25.802 -51.455 5.382   1.000 36.552  0 234 ASP A O   1 ? 
ATOM   1675 C CB  . ASP A 1 230 ? 26.655 -51.689 2.247   1.000 35.107  0 234 ASP A CB  1 ? 
ATOM   1676 C CG  . ASP A 1 230 ? 27.352 -52.559 1.211   1.000 42.181  0 234 ASP A CG  1 ? 
ATOM   1677 O OD1 . ASP A 1 230 ? 28.014 -53.530 1.625   1.000 43.745  0 234 ASP A OD1 1 ? 
ATOM   1678 O OD2 . ASP A 1 230 ? 27.217 -52.302 -0.004  1.000 42.239  0 234 ASP A OD2 1 ? 
ATOM   1679 N N   . VAL A 1 231 ? 23.965 -51.225 4.103   1.000 21.853  0 235 VAL A N   1 ? 
ATOM   1680 C CA  . VAL A 1 231 ? 23.272 -50.469 5.139   1.000 21.734  0 235 VAL A CA  1 ? 
ATOM   1681 C C   . VAL A 1 231 ? 22.893 -51.382 6.301   1.000 27.638  0 235 VAL A C   1 ? 
ATOM   1682 O O   . VAL A 1 231 ? 23.188 -51.091 7.471   1.000 24.440  0 235 VAL A O   1 ? 
ATOM   1683 C CB  . VAL A 1 231 ? 22.043 -49.764 4.545   1.000 25.806  0 235 VAL A CB  1 ? 
ATOM   1684 C CG1 . VAL A 1 231 ? 21.294 -49.033 5.611   1.000 21.966  0 235 VAL A CG1 1 ? 
ATOM   1685 C CG2 . VAL A 1 231 ? 22.471 -48.832 3.410   1.000 22.613  0 235 VAL A CG2 1 ? 
ATOM   1686 N N   . GLY A 1 232 ? 22.247 -52.507 5.989   1.000 28.701  0 236 GLY A N   1 ? 
ATOM   1687 C CA  . GLY A 1 232 ? 21.913 -53.477 7.015   1.000 25.864  0 236 GLY A CA  1 ? 
ATOM   1688 C C   . GLY A 1 232 ? 23.121 -53.975 7.786   1.000 26.608  0 236 GLY A C   1 ? 
ATOM   1689 O O   . GLY A 1 232 ? 23.060 -54.123 9.007   1.000 28.427  0 236 GLY A O   1 ? 
ATOM   1690 N N   . LYS A 1 233 ? 24.234 -54.236 7.086   1.000 28.932  0 237 LYS A N   1 ? 
ATOM   1691 C CA  . LYS A 1 233 ? 25.441 -54.724 7.758   1.000 26.537  0 237 LYS A CA  1 ? 
ATOM   1692 C C   . LYS A 1 233 ? 25.924 -53.729 8.799   1.000 29.301  0 237 LYS A C   1 ? 
ATOM   1693 O O   . LYS A 1 233 ? 26.315 -54.118 9.909   1.000 33.233  0 237 LYS A O   1 ? 
ATOM   1694 C CB  . LYS A 1 233 ? 26.567 -54.992 6.745   1.000 33.367  0 237 LYS A CB  1 ? 
ATOM   1695 C CG  . LYS A 1 233 ? 26.620 -56.393 6.098   1.000 25.732  0 237 LYS A CG  1 ? 
ATOM   1696 C CD  . LYS A 1 233 ? 27.387 -56.325 4.771   1.000 21.247  0 237 LYS A CD  1 ? 
ATOM   1697 C CE  . LYS A 1 233 ? 27.531 -57.686 4.091   1.000 22.979  0 237 LYS A CE  1 ? 
ATOM   1698 N NZ  . LYS A 1 233 ? 26.302 -58.060 3.323   1.000 24.300  0 237 LYS A NZ  1 ? 
ATOM   1699 N N   . GLY A 1 234 ? 25.893 -52.438 8.463   1.000 29.980  0 238 GLY A N   1 ? 
ATOM   1700 C CA  . GLY A 1 234 ? 26.318 -51.427 9.420   1.000 28.988  0 238 GLY A CA  1 ? 
ATOM   1701 C C   . GLY A 1 234 ? 25.322 -51.248 10.541  1.000 24.624  0 238 GLY A C   1 ? 
ATOM   1702 O O   . GLY A 1 234 ? 25.707 -51.086 11.700  1.000 27.840  0 238 GLY A O   1 ? 
ATOM   1703 N N   . CYS A 1 235 ? 24.025 -51.306 10.215  1.000 27.164  0 239 CYS A N   1 ? 
ATOM   1704 C CA  . CYS A 1 235 ? 22.995 -51.166 11.243  1.000 28.519  0 239 CYS A CA  1 ? 
ATOM   1705 C C   . CYS A 1 235 ? 23.129 -52.249 12.291  1.000 28.377  0 239 CYS A C   1 ? 
ATOM   1706 O O   . CYS A 1 235 ? 23.043 -51.978 13.497  1.000 27.990  0 239 CYS A O   1 ? 
ATOM   1707 C CB  . CYS A 1 235 ? 21.605 -51.216 10.613  1.000 24.692  0 239 CYS A CB  1 ? 
ATOM   1708 S SG  . CYS A 1 235 ? 21.205 -49.723 9.681   1.000 36.647  0 239 CYS A SG  1 ? 
ATOM   1709 N N   . ALA A 1 236 ? 23.364 -53.482 11.845  1.000 27.967  0 240 ALA A N   1 ? 
ATOM   1710 C CA  . ALA A 1 236 ? 23.441 -54.610 12.762  1.000 27.719  0 240 ALA A CA  1 ? 
ATOM   1711 C C   . ALA A 1 236 ? 24.660 -54.495 13.666  1.000 32.546  0 240 ALA A C   1 ? 
ATOM   1712 O O   . ALA A 1 236 ? 24.568 -54.741 14.876  1.000 29.830  0 240 ALA A O   1 ? 
ATOM   1713 C CB  . ALA A 1 236 ? 23.464 -55.919 11.972  1.000 19.892  0 240 ALA A CB  1 ? 
ATOM   1714 N N   . GLN A 1 237 ? 25.814 -54.132 13.095  1.000 26.830  0 241 GLN A N   1 ? 
ATOM   1715 C CA  . GLN A 1 237 ? 26.980 -53.836 13.920  1.000 29.325  0 241 GLN A CA  1 ? 
ATOM   1716 C C   . GLN A 1 237 ? 26.638 -52.799 14.979  1.000 30.962  0 241 GLN A C   1 ? 
ATOM   1717 O O   . GLN A 1 237 ? 26.905 -53.002 16.165  1.000 31.064  0 241 GLN A O   1 ? 
ATOM   1718 C CB  . GLN A 1 237 ? 28.136 -53.330 13.062  1.000 26.935  0 241 GLN A CB  1 ? 
ATOM   1719 C CG  . GLN A 1 237 ? 28.933 -54.407 12.400  1.000 26.448  0 241 GLN A CG  1 ? 
ATOM   1720 C CD  . GLN A 1 237 ? 30.222 -53.877 11.827  1.000 33.462  0 241 GLN A CD  1 ? 
ATOM   1721 O OE1 . GLN A 1 237 ? 30.989 -53.209 12.518  1.000 37.465  0 241 GLN A OE1 1 ? 
ATOM   1722 N NE2 . GLN A 1 237 ? 30.472 -54.169 10.560  1.000 41.723  0 241 GLN A NE2 1 ? 
ATOM   1723 N N   . ALA A 1 238 ? 26.036 -51.681 14.563  1.000 28.064  0 242 ALA A N   1 ? 
ATOM   1724 C CA  . ALA A 1 238 ? 25.639 -50.645 15.511  1.000 29.864  0 242 ALA A CA  1 ? 
ATOM   1725 C C   . ALA A 1 238 ? 24.878 -51.235 16.696  1.000 29.975  0 242 ALA A C   1 ? 
ATOM   1726 O O   . ALA A 1 238 ? 25.277 -51.072 17.857  1.000 27.440  0 242 ALA A O   1 ? 
ATOM   1727 C CB  . ALA A 1 238 ? 24.795 -49.583 14.808  1.000 25.579  0 242 ALA A CB  1 ? 
ATOM   1728 N N   . LEU A 1 239 ? 23.786 -51.955 16.415  1.000 22.013  0 243 LEU A N   1 ? 
ATOM   1729 C CA  . LEU A 1 239 ? 22.932 -52.398 17.509  1.000 19.805  0 243 LEU A CA  1 ? 
ATOM   1730 C C   . LEU A 1 239 ? 23.628 -53.446 18.352  1.000 26.348  0 243 LEU A C   1 ? 
ATOM   1731 O O   . LEU A 1 239 ? 23.617 -53.356 19.583  1.000 38.597  0 243 LEU A O   1 ? 
ATOM   1732 C CB  . LEU A 1 239 ? 21.608 -52.910 16.972  1.000 21.903  0 243 LEU A CB  1 ? 
ATOM   1733 C CG  . LEU A 1 239 ? 20.999 -51.723 16.250  1.000 31.717  0 243 LEU A CG  1 ? 
ATOM   1734 C CD1 . LEU A 1 239 ? 19.826 -52.154 15.414  1.000 36.970  0 243 LEU A CD1 1 ? 
ATOM   1735 C CD2 . LEU A 1 239 ? 20.604 -50.673 17.261  1.000 29.459  0 243 LEU A CD2 1 ? 
ATOM   1736 N N   . ARG A 1 240 ? 24.296 -54.411 17.719  1.000 21.737  0 244 ARG A N   1 ? 
ATOM   1737 C CA  . ARG A 1 240 ? 24.926 -55.451 18.512  1.000 29.240  0 244 ARG A CA  1 ? 
ATOM   1738 C C   . ARG A 1 240 ? 26.003 -54.876 19.424  1.000 29.454  0 244 ARG A C   1 ? 
ATOM   1739 O O   . ARG A 1 240 ? 26.230 -55.400 20.516  1.000 35.257  0 244 ARG A O   1 ? 
ATOM   1740 C CB  . ARG A 1 240 ? 25.483 -56.556 17.614  1.000 39.194  0 244 ARG A CB  1 ? 
ATOM   1741 C CG  . ARG A 1 240 ? 26.869 -56.308 17.096  1.000 60.173  0 244 ARG A CG  1 ? 
ATOM   1742 C CD  . ARG A 1 240 ? 27.482 -57.592 16.570  1.000 70.730  0 244 ARG A CD  1 ? 
ATOM   1743 N NE  . ARG A 1 240 ? 28.509 -58.118 17.459  1.000 73.104  0 244 ARG A NE  1 ? 
ATOM   1744 C CZ  . ARG A 1 240 ? 29.116 -59.285 17.279  1.000 65.305  0 244 ARG A CZ  1 ? 
ATOM   1745 N NH1 . ARG A 1 240 ? 28.791 -60.038 16.235  1.000 53.443  0 244 ARG A NH1 1 ? 
ATOM   1746 N NH2 . ARG A 1 240 ? 30.048 -59.695 18.137  1.000 66.516  0 244 ARG A NH2 1 ? 
ATOM   1747 N N   . GLY A 1 241 ? 26.637 -53.777 19.026  1.000 27.027  0 245 GLY A N   1 ? 
ATOM   1748 C CA  . GLY A 1 241 ? 27.678 -53.204 19.855  1.000 23.790  0 245 GLY A CA  1 ? 
ATOM   1749 C C   . GLY A 1 241 ? 27.156 -52.515 21.093  1.000 37.494  0 245 GLY A C   1 ? 
ATOM   1750 O O   . GLY A 1 241 ? 27.906 -52.341 22.062  1.000 41.823  0 245 GLY A O   1 ? 
ATOM   1751 N N   . GLN A 1 242 ? 25.891 -52.105 21.080  1.000 25.900  0 246 GLN A N   1 ? 
ATOM   1752 C CA  . GLN A 1 242 ? 25.259 -51.551 22.259  1.000 27.598  0 246 GLN A CA  1 ? 
ATOM   1753 C C   . GLN A 1 242 ? 24.510 -52.603 23.075  1.000 32.920  0 246 GLN A C   1 ? 
ATOM   1754 O O   . GLN A 1 242 ? 23.779 -52.239 24.007  1.000 32.001  0 246 GLN A O   1 ? 
ATOM   1755 C CB  . GLN A 1 242 ? 24.306 -50.431 21.859  1.000 36.920  0 246 GLN A CB  1 ? 
ATOM   1756 C CG  . GLN A 1 242 ? 24.953 -49.398 21.001  1.000 36.281  0 246 GLN A CG  1 ? 
ATOM   1757 C CD  . GLN A 1 242 ? 25.398 -48.239 21.794  1.000 33.128  0 246 GLN A CD  1 ? 
ATOM   1758 O OE1 . GLN A 1 242 ? 24.626 -47.322 22.049  1.000 42.566  0 246 GLN A OE1 1 ? 
ATOM   1759 N NE2 . GLN A 1 242 ? 26.644 -48.266 22.219  1.000 35.862  0 246 GLN A NE2 1 ? 
ATOM   1760 N N   . GLY A 1 243 ? 24.660 -53.889 22.740  1.000 23.653  0 247 GLY A N   1 ? 
ATOM   1761 C CA  . GLY A 1 243 ? 24.065 -54.959 23.527  1.000 23.805  0 247 GLY A CA  1 ? 
ATOM   1762 C C   . GLY A 1 243 ? 22.657 -55.393 23.144  1.000 27.538  0 247 GLY A C   1 ? 
ATOM   1763 O O   . GLY A 1 243 ? 22.011 -56.090 23.932  1.000 31.233  0 247 GLY A O   1 ? 
ATOM   1764 N N   . ALA A 1 244 ? 22.158 -55.004 21.977  1.000 19.871  0 248 ALA A N   1 ? 
ATOM   1765 C CA  . ALA A 1 244 ? 20.912 -55.564 21.479  1.000 23.590  0 248 ALA A CA  1 ? 
ATOM   1766 C C   . ALA A 1 244 ? 21.111 -56.995 20.980  1.000 29.580  0 248 ALA A C   1 ? 
ATOM   1767 O O   . ALA A 1 244 ? 22.180 -57.366 20.492  1.000 25.648  0 248 ALA A O   1 ? 
ATOM   1768 C CB  . ALA A 1 244 ? 20.359 -54.707 20.339  1.000 19.881  0 248 ALA A CB  1 ? 
ATOM   1769 N N   . THR A 1 245 ? 20.059 -57.803 21.090  1.000 29.735  0 249 THR A N   1 ? 
ATOM   1770 C CA  . THR A 1 245 ? 19.971 -59.015 20.287  1.000 25.327  0 249 THR A CA  1 ? 
ATOM   1771 C C   . THR A 1 245 ? 19.509 -58.609 18.885  1.000 24.924  0 249 THR A C   1 ? 
ATOM   1772 O O   . THR A 1 245 ? 18.438 -58.014 18.726  1.000 27.961  0 249 THR A O   1 ? 
ATOM   1773 C CB  . THR A 1 245 ? 19.005 -60.017 20.921  1.000 33.709  0 249 THR A CB  1 ? 
ATOM   1774 O OG1 . THR A 1 245 ? 19.520 -60.461 22.184  1.000 38.526  0 249 THR A OG1 1 ? 
ATOM   1775 C CG2 . THR A 1 245 ? 18.805 -61.224 20.007  1.000 20.939  0 249 THR A CG2 1 ? 
ATOM   1776 N N   . VAL A 1 246 ? 20.319 -58.876 17.871  1.000 24.540  0 250 VAL A N   1 ? 
ATOM   1777 C CA  . VAL A 1 246 ? 20.000 -58.442 16.523  1.000 20.066  0 250 VAL A CA  1 ? 
ATOM   1778 C C   . VAL A 1 246 ? 19.475 -59.630 15.737  1.000 24.640  0 250 VAL A C   1 ? 
ATOM   1779 O O   . VAL A 1 246 ? 20.063 -60.716 15.770  1.000 20.431  0 250 VAL A O   1 ? 
ATOM   1780 C CB  . VAL A 1 246 ? 21.219 -57.818 15.834  1.000 19.868  0 250 VAL A CB  1 ? 
ATOM   1781 C CG1 . VAL A 1 246 ? 20.941 -57.645 14.329  1.000 23.516  0 250 VAL A CG1 1 ? 
ATOM   1782 C CG2 . VAL A 1 246 ? 21.590 -56.495 16.512  1.000 19.742  0 250 VAL A CG2 1 ? 
ATOM   1783 N N   . LEU A 1 247 ? 18.353 -59.430 15.054  1.000 23.577  0 251 LEU A N   1 ? 
ATOM   1784 C CA  . LEU A 1 247 ? 17.807 -60.372 14.096  1.000 20.760  0 251 LEU A CA  1 ? 
ATOM   1785 C C   . LEU A 1 247 ? 17.910 -59.761 12.717  1.000 20.681  0 251 LEU A C   1 ? 
ATOM   1786 O O   . LEU A 1 247 ? 17.873 -58.542 12.566  1.000 30.183  0 251 LEU A O   1 ? 
ATOM   1787 C CB  . LEU A 1 247 ? 16.337 -60.686 14.387  1.000 22.816  0 251 LEU A CB  1 ? 
ATOM   1788 C CG  . LEU A 1 247 ? 15.932 -61.123 15.790  1.000 25.916  0 251 LEU A CG  1 ? 
ATOM   1789 C CD1 . LEU A 1 247 ? 14.387 -61.238 15.890  1.000 21.818  0 251 LEU A CD1 1 ? 
ATOM   1790 C CD2 . LEU A 1 247 ? 16.619 -62.432 16.086  1.000 21.532  0 251 LEU A CD2 1 ? 
ATOM   1791 N N   . VAL A 1 248 ? 17.962 -60.616 11.708  1.000 26.145  0 252 VAL A N   1 ? 
ATOM   1792 C CA  . VAL A 1 248 ? 18.168 -60.195 10.330  1.000 20.881  0 252 VAL A CA  1 ? 
ATOM   1793 C C   . VAL A 1 248 ? 17.160 -60.927 9.459   1.000 27.843  0 252 VAL A C   1 ? 
ATOM   1794 O O   . VAL A 1 248 ? 16.944 -62.137 9.625   1.000 27.566  0 252 VAL A O   1 ? 
ATOM   1795 C CB  . VAL A 1 248 ? 19.625 -60.484 9.866   1.000 20.739  0 252 VAL A CB  1 ? 
ATOM   1796 C CG1 . VAL A 1 248 ? 19.801 -60.216 8.413   1.000 20.842  0 252 VAL A CG1 1 ? 
ATOM   1797 C CG2 . VAL A 1 248 ? 20.620 -59.662 10.641  1.000 20.413  0 252 VAL A CG2 1 ? 
ATOM   1798 N N   . ALA A 1 249 ? 16.545 -60.199 8.528   1.000 25.882  0 253 ALA A N   1 ? 
ATOM   1799 C CA  . ALA A 1 249 ? 15.750 -60.800 7.461   1.000 21.853  0 253 ALA A CA  1 ? 
ATOM   1800 C C   . ALA A 1 249 ? 16.436 -60.594 6.117   1.000 28.769  0 253 ALA A C   1 ? 
ATOM   1801 O O   . ALA A 1 249 ? 17.054 -59.556 5.872   1.000 21.605  0 253 ALA A O   1 ? 
ATOM   1802 C CB  . ALA A 1 249 ? 14.341 -60.221 7.395   1.000 22.134  0 253 ALA A CB  1 ? 
ATOM   1803 N N   . GLU A 1 250 ? 16.309 -61.584 5.241   1.000 25.766  0 254 GLU A N   1 ? 
ATOM   1804 C CA  . GLU A 1 250 ? 16.945 -61.515 3.943   1.000 22.308  0 254 GLU A CA  1 ? 
ATOM   1805 C C   . GLU A 1 250 ? 16.176 -62.350 2.936   1.000 32.120  0 254 GLU A C   1 ? 
ATOM   1806 O O   . GLU A 1 250 ? 15.576 -63.380 3.274   1.000 25.914  0 254 GLU A O   1 ? 
ATOM   1807 C CB  . GLU A 1 250 ? 18.408 -61.996 3.992   1.000 24.121  0 254 GLU A CB  1 ? 
ATOM   1808 C CG  . GLU A 1 250 ? 19.397 -60.856 3.970   1.000 21.745  0 254 GLU A CG  1 ? 
ATOM   1809 C CD  . GLU A 1 250 ? 19.407 -60.100 2.641   1.000 28.051  0 254 GLU A CD  1 ? 
ATOM   1810 O OE1 . GLU A 1 250 ? 18.752 -60.543 1.652   1.000 22.321  0 254 GLU A OE1 1 ? 
ATOM   1811 O OE2 . GLU A 1 250 ? 20.073 -59.038 2.603   1.000 21.755  0 254 GLU A OE2 1 ? 
ATOM   1812 N N   . ILE A 1 251 ? 16.209 -61.882 1.687   1.000 23.045  0 255 ILE A N   1 ? 
ATOM   1813 C CA  . ILE A 1 251 ? 15.772 -62.676 0.550   1.000 30.212  0 255 ILE A CA  1 ? 
ATOM   1814 C C   . ILE A 1 251 ? 16.951 -63.233 -0.231  1.000 35.473  0 255 ILE A C   1 ? 
ATOM   1815 O O   . ILE A 1 251 ? 16.780 -64.219 -0.966  1.000 39.289  0 255 ILE A O   1 ? 
ATOM   1816 C CB  . ILE A 1 251 ? 14.864 -61.845 -0.375  1.000 28.611  0 255 ILE A CB  1 ? 
ATOM   1817 C CG1 . ILE A 1 251 ? 15.603 -60.585 -0.859  1.000 24.492  0 255 ILE A CG1 1 ? 
ATOM   1818 C CG2 . ILE A 1 251 ? 13.587 -61.481 0.365   1.000 28.324  0 255 ILE A CG2 1 ? 
ATOM   1819 C CD1 . ILE A 1 251 ? 16.144 -60.659 -2.263  1.000 23.948  0 255 ILE A CD1 1 ? 
ATOM   1820 N N   . ASP A 1 252 ? 18.134 -62.636 -0.089  1.000 30.988  0 256 ASP A N   1 ? 
ATOM   1821 C CA  . ASP A 1 252 ? 19.330 -63.064 -0.797  1.000 25.982  0 256 ASP A CA  1 ? 
ATOM   1822 C C   . ASP A 1 252 ? 20.063 -64.104 0.046   1.000 28.985  0 256 ASP A C   1 ? 
ATOM   1823 O O   . ASP A 1 252 ? 20.566 -63.766 1.128   1.000 35.894  0 256 ASP A O   1 ? 
ATOM   1824 C CB  . ASP A 1 252 ? 20.233 -61.863 -1.066  1.000 32.704  0 256 ASP A CB  1 ? 
ATOM   1825 C CG  . ASP A 1 252 ? 21.449 -62.202 -1.918  1.000 32.225  0 256 ASP A CG  1 ? 
ATOM   1826 O OD1 . ASP A 1 252 ? 22.031 -63.310 -1.789  1.000 33.746  0 256 ASP A OD1 1 ? 
ATOM   1827 O OD2 . ASP A 1 252 ? 21.826 -61.341 -2.729  1.000 31.843  0 256 ASP A OD2 1 ? 
ATOM   1828 N N   . PRO A 1 253 ? 20.179 -65.350 -0.418  1.000 27.664  0 257 PRO A N   1 ? 
ATOM   1829 C CA  . PRO A 1 253 ? 20.834 -66.380 0.400   1.000 25.487  0 257 PRO A CA  1 ? 
ATOM   1830 C C   . PRO A 1 253 ? 22.286 -66.073 0.733   1.000 33.788  0 257 PRO A C   1 ? 
ATOM   1831 O O   . PRO A 1 253 ? 22.761 -66.519 1.788   1.000 32.978  0 257 PRO A O   1 ? 
ATOM   1832 C CB  . PRO A 1 253 ? 20.719 -67.644 -0.470  1.000 24.324  0 257 PRO A CB  1 ? 
ATOM   1833 C CG  . PRO A 1 253 ? 20.492 -67.170 -1.829  1.000 24.548  0 257 PRO A CG  1 ? 
ATOM   1834 C CD  . PRO A 1 253 ? 19.779 -65.860 -1.742  1.000 26.077  0 257 PRO A CD  1 ? 
ATOM   1835 N N   . ILE A 1 254 ? 23.013 -65.343 -0.124  1.000 34.194  0 258 ILE A N   1 ? 
ATOM   1836 C CA  . ILE A 1 254 ? 24.410 -65.031 0.183   1.000 34.191  0 258 ILE A CA  1 ? 
ATOM   1837 C C   . ILE A 1 254 ? 24.493 -64.055 1.354   1.000 36.246  0 258 ILE A C   1 ? 
ATOM   1838 O O   . ILE A 1 254 ? 25.238 -64.284 2.317   1.000 40.744  0 258 ILE A O   1 ? 
ATOM   1839 C CB  . ILE A 1 254 ? 25.150 -64.498 -1.059  1.000 34.520  0 258 ILE A CB  1 ? 
ATOM   1840 C CG1 . ILE A 1 254 ? 25.285 -65.601 -2.116  1.000 31.196  0 258 ILE A CG1 1 ? 
ATOM   1841 C CG2 . ILE A 1 254 ? 26.534 -63.986 -0.684  1.000 23.055  0 258 ILE A CG2 1 ? 
ATOM   1842 C CD1 . ILE A 1 254 ? 25.667 -65.085 -3.490  1.000 30.656  0 258 ILE A CD1 1 ? 
ATOM   1843 N N   . CYS A 1 255 ? 23.714 -62.969 1.310   1.000 31.988  0 259 CYS A N   1 ? 
ATOM   1844 C CA  . CYS A 1 255 ? 23.728 -62.037 2.438   1.000 31.654  0 259 CYS A CA  1 ? 
ATOM   1845 C C   . CYS A 1 255 ? 23.182 -62.691 3.690   1.000 35.849  0 259 CYS A C   1 ? 
ATOM   1846 O O   . CYS A 1 255 ? 23.677 -62.413 4.795   1.000 28.456  0 259 CYS A O   1 ? 
ATOM   1847 C CB  . CYS A 1 255 ? 22.933 -60.769 2.120   1.000 27.198  0 259 CYS A CB  1 ? 
ATOM   1848 S SG  . CYS A 1 255 ? 23.500 -59.963 0.590   1.000 40.452  0 259 CYS A SG  1 ? 
ATOM   1849 N N   . ALA A 1 256 ? 22.188 -63.580 3.530   1.000 27.435  0 260 ALA A N   1 ? 
ATOM   1850 C CA  . ALA A 1 256 ? 21.663 -64.325 4.675   1.000 22.047  0 260 ALA A CA  1 ? 
ATOM   1851 C C   . ALA A 1 256 ? 22.757 -65.138 5.359   1.000 31.154  0 260 ALA A C   1 ? 
ATOM   1852 O O   . ALA A 1 256 ? 22.850 -65.159 6.594   1.000 40.307  0 260 ALA A O   1 ? 
ATOM   1853 C CB  . ALA A 1 256 ? 20.525 -65.240 4.226   1.000 22.529  0 260 ALA A CB  1 ? 
ATOM   1854 N N   . LEU A 1 257 ? 23.592 -65.817 4.568   1.000 25.243  0 261 LEU A N   1 ? 
ATOM   1855 C CA  . LEU A 1 257 ? 24.677 -66.620 5.122   1.000 28.911  0 261 LEU A CA  1 ? 
ATOM   1856 C C   . LEU A 1 257 ? 25.722 -65.748 5.820   1.000 32.035  0 261 LEU A C   1 ? 
ATOM   1857 O O   . LEU A 1 257 ? 26.205 -66.111 6.901   1.000 31.999  0 261 LEU A O   1 ? 
ATOM   1858 C CB  . LEU A 1 257 ? 25.304 -67.475 4.013   1.000 27.201  0 261 LEU A CB  1 ? 
ATOM   1859 C CG  . LEU A 1 257 ? 26.269 -68.586 4.421   1.000 29.196  0 261 LEU A CG  1 ? 
ATOM   1860 C CD1 . LEU A 1 257 ? 25.716 -69.465 5.508   1.000 23.426  0 261 LEU A CD1 1 ? 
ATOM   1861 C CD2 . LEU A 1 257 ? 26.641 -69.416 3.221   1.000 26.224  0 261 LEU A CD2 1 ? 
ATOM   1862 N N   . GLN A 1 258 ? 26.056 -64.577 5.250   1.000 26.285  0 262 GLN A N   1 ? 
ATOM   1863 C CA  . GLN A 1 258 ? 26.988 -63.671 5.937   1.000 24.871  0 262 GLN A CA  1 ? 
ATOM   1864 C C   . GLN A 1 258 ? 26.461 -63.312 7.315   1.000 30.083  0 262 GLN A C   1 ? 
ATOM   1865 O O   . GLN A 1 258 ? 27.202 -63.351 8.304   1.000 28.877  0 262 GLN A O   1 ? 
ATOM   1866 C CB  . GLN A 1 258 ? 27.221 -62.380 5.143   1.000 21.447  0 262 GLN A CB  1 ? 
ATOM   1867 C CG  . GLN A 1 258 ? 27.765 -62.525 3.750   1.000 21.784  0 262 GLN A CG  1 ? 
ATOM   1868 C CD  . GLN A 1 258 ? 27.800 -61.192 3.019   1.000 30.864  0 262 GLN A CD  1 ? 
ATOM   1869 O OE1 . GLN A 1 258 ? 26.752 -60.598 2.733   1.000 21.708  0 262 GLN A OE1 1 ? 
ATOM   1870 N NE2 . GLN A 1 258 ? 29.003 -60.711 2.717   1.000 21.950  0 262 GLN A NE2 1 ? 
ATOM   1871 N N   . ALA A 1 259 ? 25.176 -62.934 7.387   1.000 21.108  0 263 ALA A N   1 ? 
ATOM   1872 C CA  . ALA A 1 259 ? 24.574 -62.540 8.656   1.000 26.753  0 263 ALA A CA  1 ? 
ATOM   1873 C C   . ALA A 1 259 ? 24.605 -63.695 9.650   1.000 35.725  0 263 ALA A C   1 ? 
ATOM   1874 O O   . ALA A 1 259 ? 25.002 -63.523 10.814  1.000 20.866  0 263 ALA A O   1 ? 
ATOM   1875 C CB  . ALA A 1 259 ? 23.141 -62.045 8.431   1.000 20.842  0 263 ALA A CB  1 ? 
ATOM   1876 N N   . ALA A 1 260 ? 24.212 -64.892 9.193   1.000 21.397  0 264 ALA A N   1 ? 
ATOM   1877 C CA  . ALA A 1 260 ? 24.275 -66.068 10.058  1.000 25.898  0 264 ALA A CA  1 ? 
ATOM   1878 C C   . ALA A 1 260 ? 25.691 -66.307 10.563  1.000 28.975  0 264 ALA A C   1 ? 
ATOM   1879 O O   . ALA A 1 260 ? 25.894 -66.659 11.729  1.000 35.496  0 264 ALA A O   1 ? 
ATOM   1880 C CB  . ALA A 1 260 ? 23.761 -67.299 9.313   1.000 27.959  0 264 ALA A CB  1 ? 
ATOM   1881 N N   . MET A 1 261 ? 26.688 -66.095 9.710   1.000 24.882  0 265 MET A N   1 ? 
ATOM   1882 C CA  . MET A 1 261 ? 28.041 -66.395 10.138  1.000 24.340  0 265 MET A CA  1 ? 
ATOM   1883 C C   . MET A 1 261 ? 28.664 -65.282 10.953  1.000 23.192  0 265 MET A C   1 ? 
ATOM   1884 O O   . MET A 1 261 ? 29.765 -65.469 11.476  1.000 22.197  0 265 MET A O   1 ? 
ATOM   1885 C CB  . MET A 1 261 ? 28.906 -66.713 8.933   1.000 29.954  0 265 MET A CB  1 ? 
ATOM   1886 C CG  . MET A 1 261 ? 28.312 -67.836 8.155   1.000 38.476  0 265 MET A CG  1 ? 
ATOM   1887 S SD  . MET A 1 261 ? 29.526 -69.044 7.790   1.000 47.266  0 265 MET A SD  1 ? 
ATOM   1888 C CE  . MET A 1 261 ? 29.555 -69.896 9.332   1.000 50.906  0 265 MET A CE  1 ? 
ATOM   1889 N N   . GLU A 1 262 ? 28.000 -64.140 11.070  1.000 26.248  0 266 GLU A N   1 ? 
ATOM   1890 C CA  . GLU A 1 262 ? 28.378 -63.154 12.063  1.000 24.979  0 266 GLU A CA  1 ? 
ATOM   1891 C C   . GLU A 1 262 ? 27.596 -63.328 13.349  1.000 24.629  0 266 GLU A C   1 ? 
ATOM   1892 O O   . GLU A 1 262 ? 27.622 -62.433 14.192  1.000 24.124  0 266 GLU A O   1 ? 
ATOM   1893 C CB  . GLU A 1 262 ? 28.181 -61.732 11.521  1.000 33.957  0 266 GLU A CB  1 ? 
ATOM   1894 C CG  . GLU A 1 262 ? 28.807 -61.498 10.169  1.000 41.147  0 266 GLU A CG  1 ? 
ATOM   1895 C CD  . GLU A 1 262 ? 30.273 -61.184 10.270  1.000 52.127  0 266 GLU A CD  1 ? 
ATOM   1896 O OE1 . GLU A 1 262 ? 30.903 -61.012 9.203   1.000 58.128  0 266 GLU A OE1 1 ? 
ATOM   1897 O OE2 . GLU A 1 262 ? 30.792 -61.099 11.413  1.000 53.122  0 266 GLU A OE2 1 ? 
ATOM   1898 N N   . GLY A 1 263 ? 26.844 -64.422 13.483  1.000 26.072  0 267 GLY A N   1 ? 
ATOM   1899 C CA  . GLY A 1 263 ? 26.120 -64.724 14.698  1.000 30.206  0 267 GLY A CA  1 ? 
ATOM   1900 C C   . GLY A 1 263 ? 24.711 -64.173 14.809  1.000 28.151  0 267 GLY A C   1 ? 
ATOM   1901 O O   . GLY A 1 263 ? 24.078 -64.352 15.857  1.000 31.622  0 267 GLY A O   1 ? 
ATOM   1902 N N   . TYR A 1 264 ? 24.194 -63.508 13.789  1.000 25.922  0 268 TYR A N   1 ? 
ATOM   1903 C CA  . TYR A 1 264 ? 22.802 -63.098 13.846  1.000 25.161  0 268 TYR A CA  1 ? 
ATOM   1904 C C   . TYR A 1 264 ? 21.894 -64.255 13.455  1.000 30.433  0 268 TYR A C   1 ? 
ATOM   1905 O O   . TYR A 1 264 ? 22.238 -65.096 12.616  1.000 40.100  0 268 TYR A O   1 ? 
ATOM   1906 C CB  . TYR A 1 264 ? 22.560 -61.886 12.943  1.000 26.793  0 268 TYR A CB  1 ? 
ATOM   1907 C CG  . TYR A 1 264 ? 23.570 -60.789 13.161  1.000 26.479  0 268 TYR A CG  1 ? 
ATOM   1908 C CD1 . TYR A 1 264 ? 23.641 -60.107 14.369  1.000 25.537  0 268 TYR A CD1 1 ? 
ATOM   1909 C CD2 . TYR A 1 264 ? 24.473 -60.456 12.169  1.000 20.176  0 268 TYR A CD2 1 ? 
ATOM   1910 C CE1 . TYR A 1 264 ? 24.584 -59.101 14.568  1.000 31.699  0 268 TYR A CE1 1 ? 
ATOM   1911 C CE2 . TYR A 1 264 ? 25.406 -59.469 12.349  1.000 20.047  0 268 TYR A CE2 1 ? 
ATOM   1912 C CZ  . TYR A 1 264 ? 25.464 -58.786 13.547  1.000 35.031  0 268 TYR A CZ  1 ? 
ATOM   1913 O OH  . TYR A 1 264 ? 26.421 -57.804 13.715  1.000 34.988  0 268 TYR A OH  1 ? 
ATOM   1914 N N   . ARG A 1 265 ? 20.732 -64.310 14.097  1.000 28.361  0 269 ARG A N   1 ? 
ATOM   1915 C CA  . ARG A 1 265 ? 19.681 -65.219 13.657  1.000 29.580  0 269 ARG A CA  1 ? 
ATOM   1916 C C   . ARG A 1 265 ? 18.959 -64.613 12.466  1.000 21.718  0 269 ARG A C   1 ? 
ATOM   1917 O O   . ARG A 1 265 ? 18.556 -63.452 12.506  1.000 35.396  0 269 ARG A O   1 ? 
ATOM   1918 C CB  . ARG A 1 265 ? 18.688 -65.494 14.795  1.000 33.151  0 269 ARG A CB  1 ? 
ATOM   1919 C CG  . ARG A 1 265 ? 19.276 -66.236 15.974  1.000 22.268  0 269 ARG A CG  1 ? 
ATOM   1920 C CD  . ARG A 1 265 ? 19.394 -67.740 15.708  1.000 29.111  0 269 ARG A CD  1 ? 
ATOM   1921 N NE  . ARG A 1 265 ? 20.703 -68.083 15.160  1.000 35.307  0 269 ARG A NE  1 ? 
ATOM   1922 C CZ  . ARG A 1 265 ? 20.995 -69.213 14.517  1.000 36.033  0 269 ARG A CZ  1 ? 
ATOM   1923 N NH1 . ARG A 1 265 ? 20.066 -70.151 14.329  1.000 37.102  0 269 ARG A NH1 1 ? 
ATOM   1924 N NH2 . ARG A 1 265 ? 22.231 -69.402 14.063  1.000 33.236  0 269 ARG A NH2 1 ? 
ATOM   1925 N N   . VAL A 1 266 ? 18.818 -65.380 11.401  1.000 25.527  0 270 VAL A N   1 ? 
ATOM   1926 C CA  . VAL A 1 266 ? 18.137 -64.914 10.202  1.000 23.132  0 270 VAL A CA  1 ? 
ATOM   1927 C C   . VAL A 1 266 ? 16.706 -65.423 10.247  1.000 27.932  0 270 VAL A C   1 ? 
ATOM   1928 O O   . VAL A 1 266 ? 16.465 -66.634 10.247  1.000 32.159  0 270 VAL A O   1 ? 
ATOM   1929 C CB  . VAL A 1 266 ? 18.853 -65.373 8.925   1.000 22.218  0 270 VAL A CB  1 ? 
ATOM   1930 C CG1 . VAL A 1 266 ? 18.120 -64.878 7.730   1.000 24.677  0 270 VAL A CG1 1 ? 
ATOM   1931 C CG2 . VAL A 1 266 ? 20.259 -64.849 8.903   1.000 21.800  0 270 VAL A CG2 1 ? 
ATOM   1932 N N   . VAL A 1 267 ? 15.756 -64.500 10.304  1.000 35.288  0 271 VAL A N   1 ? 
ATOM   1933 C CA  . VAL A 1 267 ? 14.357 -64.820 10.561  1.000 40.468  0 271 VAL A CA  1 ? 
ATOM   1934 C C   . VAL A 1 267 ? 13.485 -64.020 9.598   1.000 32.296  0 271 VAL A C   1 ? 
ATOM   1935 O O   . VAL A 1 267 ? 13.945 -63.119 8.899   1.000 31.688  0 271 VAL A O   1 ? 
ATOM   1936 C CB  . VAL A 1 267 ? 13.958 -64.514 12.025  1.000 23.024  0 271 VAL A CB  1 ? 
ATOM   1937 C CG1 . VAL A 1 267 ? 14.793 -65.322 12.990  1.000 23.029  0 271 VAL A CG1 1 ? 
ATOM   1938 C CG2 . VAL A 1 267 ? 14.123 -63.022 12.286  1.000 23.521  0 271 VAL A CG2 1 ? 
ATOM   1939 N N   . THR A 1 268 ? 12.203 -64.340 9.581   1.000 23.729  0 272 THR A N   1 ? 
ATOM   1940 C CA  . THR A 1 268 ? 11.264 -63.534 8.818   1.000 23.890  0 272 THR A CA  1 ? 
ATOM   1941 C C   . THR A 1 268 ? 10.416 -62.685 9.754   1.000 26.848  0 272 THR A C   1 ? 
ATOM   1942 O O   . THR A 1 268 ? 10.096 -63.080 10.881  1.000 32.559  0 272 THR A O   1 ? 
ATOM   1943 C CB  . THR A 1 268 ? 10.348 -64.394 7.950   1.000 34.283  0 272 THR A CB  1 ? 
ATOM   1944 O OG1 . THR A 1 268 ? 9.456  -65.128 8.796   1.000 34.920  0 272 THR A OG1 1 ? 
ATOM   1945 C CG2 . THR A 1 268 ? 11.161 -65.350 7.049   1.000 24.766  0 272 THR A CG2 1 ? 
ATOM   1946 N N   . LEU A 1 269 ? 10.063 -61.499 9.268   1.000 24.495  0 273 LEU A N   1 ? 
ATOM   1947 C CA  . LEU A 1 269 ? 9.129  -60.663 10.003  1.000 28.145  0 273 LEU A CA  1 ? 
ATOM   1948 C C   . LEU A 1 269 ? 7.790  -61.383 10.206  1.000 30.827  0 273 LEU A C   1 ? 
ATOM   1949 O O   . LEU A 1 269 ? 7.186  -61.291 11.289  1.000 26.345  0 273 LEU A O   1 ? 
ATOM   1950 C CB  . LEU A 1 269 ? 8.957  -59.336 9.271   1.000 23.692  0 273 LEU A CB  1 ? 
ATOM   1951 C CG  . LEU A 1 269 ? 8.055  -58.350 9.988   1.000 30.554  0 273 LEU A CG  1 ? 
ATOM   1952 C CD1 . LEU A 1 269 ? 8.464  -58.318 11.440  1.000 31.680  0 273 LEU A CD1 1 ? 
ATOM   1953 C CD2 . LEU A 1 269 ? 8.139  -56.967 9.363   1.000 33.965  0 273 LEU A CD2 1 ? 
ATOM   1954 N N   . ASP A 1 270 ? 7.320  -62.125 9.188   1.000 30.288  0 274 ASP A N   1 ? 
ATOM   1955 C CA  . ASP A 1 270 ? 6.102  -62.927 9.368   1.000 30.169  0 274 ASP A CA  1 ? 
ATOM   1956 C C   . ASP A 1 270 ? 6.163  -63.742 10.657  1.000 30.846  0 274 ASP A C   1 ? 
ATOM   1957 O O   . ASP A 1 270 ? 5.195  -63.786 11.419  1.000 33.799  0 274 ASP A O   1 ? 
ATOM   1958 C CB  . ASP A 1 270 ? 5.878  -63.865 8.180   1.000 32.699  0 274 ASP A CB  1 ? 
ATOM   1959 C CG  . ASP A 1 270 ? 5.463  -63.129 6.923   1.000 36.431  0 274 ASP A CG  1 ? 
ATOM   1960 O OD1 . ASP A 1 270 ? 5.095  -61.944 7.034   1.000 36.749  0 274 ASP A OD1 1 ? 
ATOM   1961 O OD2 . ASP A 1 270 ? 5.534  -63.724 5.822   1.000 37.078  0 274 ASP A OD2 1 ? 
ATOM   1962 N N   . ASP A 1 271 ? 7.316  -64.344 10.947  1.000 34.007  0 275 ASP A N   1 ? 
ATOM   1963 C CA  . ASP A 1 271 ? 7.453  -65.169 12.140  1.000 27.772  0 275 ASP A CA  1 ? 
ATOM   1964 C C   . ASP A 1 271 ? 7.644  -64.346 13.421  1.000 35.252  0 275 ASP A C   1 ? 
ATOM   1965 O O   . ASP A 1 271 ? 7.149  -64.744 14.474  1.000 41.100  0 275 ASP A O   1 ? 
ATOM   1966 C CB  . ASP A 1 271 ? 8.623  -66.144 11.967  1.000 37.470  0 275 ASP A CB  1 ? 
ATOM   1967 C CG  . ASP A 1 271 ? 8.362  -67.213 10.902  1.000 48.201  0 275 ASP A CG  1 ? 
ATOM   1968 O OD1 . ASP A 1 271 ? 7.197  -67.394 10.491  1.000 60.447  0 275 ASP A OD1 1 ? 
ATOM   1969 O OD2 . ASP A 1 271 ? 9.326  -67.880 10.469  1.000 46.611  0 275 ASP A OD2 1 ? 
ATOM   1970 N N   . VAL A 1 272 ? 8.360  -63.219 13.391  1.000 32.117  0 276 VAL A N   1 ? 
ATOM   1971 C CA  . VAL A 1 272 ? 8.864  -62.646 14.641  1.000 32.601  0 276 VAL A CA  1 ? 
ATOM   1972 C C   . VAL A 1 272 ? 8.208  -61.314 14.989  1.000 32.222  0 276 VAL A C   1 ? 
ATOM   1973 O O   . VAL A 1 272 ? 8.625  -60.665 15.957  1.000 32.462  0 276 VAL A O   1 ? 
ATOM   1974 C CB  . VAL A 1 272 ? 10.402 -62.501 14.637  1.000 28.825  0 276 VAL A CB  1 ? 
ATOM   1975 C CG1 . VAL A 1 272 ? 11.074 -63.812 14.351  1.000 23.816  0 276 VAL A CG1 1 ? 
ATOM   1976 C CG2 . VAL A 1 272 ? 10.872 -61.420 13.660  1.000 25.321  0 276 VAL A CG2 1 ? 
ATOM   1977 N N   . ALA A 1 273 ? 7.171  -60.901 14.258  1.000 32.691  0 277 ALA A N   1 ? 
ATOM   1978 C CA  . ALA A 1 273 ? 6.611  -59.565 14.464  1.000 29.504  0 277 ALA A CA  1 ? 
ATOM   1979 C C   . ALA A 1 273 ? 6.213  -59.301 15.925  1.000 32.341  0 277 ALA A C   1 ? 
ATOM   1980 O O   . ALA A 1 273 ? 6.328  -58.169 16.410  1.000 33.841  0 277 ALA A O   1 ? 
ATOM   1981 C CB  . ALA A 1 273 ? 5.423  -59.360 13.535  1.000 25.616  0 277 ALA A CB  1 ? 
ATOM   1982 N N   . GLU A 1 274 ? 5.795  -60.327 16.662  1.000 30.164  0 278 GLU A N   1 ? 
ATOM   1983 C CA  . GLU A 1 274 ? 5.427  -60.109 18.061  1.000 33.586  0 278 GLU A CA  1 ? 
ATOM   1984 C C   . GLU A 1 274 ? 6.621  -59.995 19.005  1.000 39.536  0 278 GLU A C   1 ? 
ATOM   1985 O O   . GLU A 1 274 ? 6.432  -59.606 20.160  1.000 37.984  0 278 GLU A O   1 ? 
ATOM   1986 C CB  . GLU A 1 274 ? 4.535  -61.240 18.567  1.000 29.372  0 278 GLU A CB  1 ? 
ATOM   1987 C CG  . GLU A 1 274 ? 3.129  -61.247 17.979  1.000 34.286  0 278 GLU A CG  1 ? 
ATOM   1988 C CD  . GLU A 1 274 ? 3.016  -62.226 16.845  1.000 42.329  0 278 GLU A CD  1 ? 
ATOM   1989 O OE1 . GLU A 1 274 ? 1.879  -62.562 16.453  1.000 47.295  0 278 GLU A OE1 1 ? 
ATOM   1990 O OE2 . GLU A 1 274 ? 4.085  -62.665 16.351  1.000 40.729  0 278 GLU A OE2 1 ? 
ATOM   1991 N N   . GLN A 1 275 ? 7.832  -60.325 18.555  1.000 33.133  0 279 GLN A N   1 ? 
ATOM   1992 C CA  . GLN A 1 275 ? 8.969  -60.458 19.447  1.000 33.249  0 279 GLN A CA  1 ? 
ATOM   1993 C C   . GLN A 1 275 ? 9.923  -59.276 19.405  1.000 30.059  0 279 GLN A C   1 ? 
ATOM   1994 O O   . GLN A 1 275 ? 10.821 -59.199 20.245  1.000 36.175  0 279 GLN A O   1 ? 
ATOM   1995 C CB  . GLN A 1 275 ? 9.763  -61.727 19.115  1.000 31.475  0 279 GLN A CB  1 ? 
ATOM   1996 C CG  . GLN A 1 275 ? 8.946  -62.996 19.009  1.000 33.399  0 279 GLN A CG  1 ? 
ATOM   1997 C CD  . GLN A 1 275 ? 9.673  -64.040 18.188  1.000 51.769  0 279 GLN A CD  1 ? 
ATOM   1998 O OE1 . GLN A 1 275 ? 10.904 -63.992 18.054  1.000 63.129  0 279 GLN A OE1 1 ? 
ATOM   1999 N NE2 . GLN A 1 275 ? 8.922  -64.967 17.599  1.000 50.117  0 279 GLN A NE2 1 ? 
ATOM   2000 N N   . VAL A 1 276 ? 9.763  -58.366 18.483  1.000 25.974  0 280 VAL A N   1 ? 
ATOM   2001 C CA  . VAL A 1 276 ? 10.780 -57.356 18.247  1.000 32.796  0 280 VAL A CA  1 ? 
ATOM   2002 C C   . VAL A 1 276 ? 10.433 -56.068 18.984  1.000 35.223  0 280 VAL A C   1 ? 
ATOM   2003 O O   . VAL A 1 276 ? 9.273  -55.649 19.027  1.000 38.828  0 280 VAL A O   1 ? 
ATOM   2004 C CB  . VAL A 1 276 ? 10.941 -57.141 16.735  1.000 28.253  0 280 VAL A CB  1 ? 
ATOM   2005 C CG1 . VAL A 1 276 ? 11.405 -58.455 16.118  1.000 22.205  0 280 VAL A CG1 1 ? 
ATOM   2006 C CG2 . VAL A 1 276 ? 9.619  -56.719 16.133  1.000 24.848  0 280 VAL A CG2 1 ? 
ATOM   2007 N N   . ASP A 1 277 ? 11.444 -55.448 19.588  1.000 34.183  0 281 ASP A N   1 ? 
ATOM   2008 C CA  . ASP A 1 277 ? 11.286 -54.131 20.193  1.000 30.064  0 281 ASP A CA  1 ? 
ATOM   2009 C C   . ASP A 1 277 ? 11.552 -53.007 19.212  1.000 27.380  0 281 ASP A C   1 ? 
ATOM   2010 O O   . ASP A 1 277 ? 10.990 -51.915 19.355  1.000 25.564  0 281 ASP A O   1 ? 
ATOM   2011 C CB  . ASP A 1 277 ? 12.236 -53.960 21.378  1.000 31.375  0 281 ASP A CB  1 ? 
ATOM   2012 C CG  . ASP A 1 277 ? 11.986 -54.970 22.483  1.000 38.649  0 281 ASP A CG  1 ? 
ATOM   2013 O OD1 . ASP A 1 277 ? 10.875 -54.952 23.065  1.000 41.637  0 281 ASP A OD1 1 ? 
ATOM   2014 O OD2 . ASP A 1 277 ? 12.906 -55.780 22.763  1.000 33.904  0 281 ASP A OD2 1 ? 
ATOM   2015 N N   . ILE A 1 278 ? 12.417 -53.242 18.238  1.000 30.554  0 282 ILE A N   1 ? 
ATOM   2016 C CA  . ILE A 1 278 ? 12.811 -52.230 17.268  1.000 28.335  0 282 ILE A CA  1 ? 
ATOM   2017 C C   . ILE A 1 278 ? 12.845 -52.897 15.913  1.000 28.422  0 282 ILE A C   1 ? 
ATOM   2018 O O   . ILE A 1 278 ? 13.315 -54.032 15.796  1.000 29.314  0 282 ILE A O   1 ? 
ATOM   2019 C CB  . ILE A 1 278 ? 14.193 -51.629 17.593  1.000 28.195  0 282 ILE A CB  1 ? 
ATOM   2020 C CG1 . ILE A 1 278 ? 14.136 -50.822 18.881  1.000 28.959  0 282 ILE A CG1 1 ? 
ATOM   2021 C CG2 . ILE A 1 278 ? 14.710 -50.793 16.424  1.000 23.200  0 282 ILE A CG2 1 ? 
ATOM   2022 C CD1 . ILE A 1 278 ? 15.486 -50.471 19.402  1.000 21.231  0 282 ILE A CD1 1 ? 
ATOM   2023 N N   . VAL A 1 279 ? 12.368 -52.196 14.889  1.000 21.482  0 283 VAL A N   1 ? 
ATOM   2024 C CA  . VAL A 1 279 ? 12.474 -52.676 13.519  1.000 23.442  0 283 VAL A CA  1 ? 
ATOM   2025 C C   . VAL A 1 279 ? 13.095 -51.599 12.649  1.000 21.471  0 283 VAL A C   1 ? 
ATOM   2026 O O   . VAL A 1 279 ? 12.628 -50.456 12.651  1.000 28.367  0 283 VAL A O   1 ? 
ATOM   2027 C CB  . VAL A 1 279 ? 11.113 -53.090 12.941  1.000 27.056  0 283 VAL A CB  1 ? 
ATOM   2028 C CG1 . VAL A 1 279 ? 11.267 -53.348 11.463  1.000 22.039  0 283 VAL A CG1 1 ? 
ATOM   2029 C CG2 . VAL A 1 279 ? 10.588 -54.316 13.671  1.000 22.111  0 283 VAL A CG2 1 ? 
ATOM   2030 N N   . VAL A 1 280 ? 14.117 -51.980 11.876  1.000 21.250  0 284 VAL A N   1 ? 
ATOM   2031 C CA  . VAL A 1 280 ? 14.799 -51.101 10.934  1.000 21.297  0 284 VAL A CA  1 ? 
ATOM   2032 C C   . VAL A 1 280 ? 14.684 -51.704 9.542   1.000 23.082  0 284 VAL A C   1 ? 
ATOM   2033 O O   . VAL A 1 280 ? 15.190 -52.804 9.291   1.000 30.941  0 284 VAL A O   1 ? 
ATOM   2034 C CB  . VAL A 1 280 ? 16.277 -50.914 11.304  1.000 30.275  0 284 VAL A CB  1 ? 
ATOM   2035 C CG1 . VAL A 1 280 ? 16.953 -50.017 10.281  1.000 24.245  0 284 VAL A CG1 1 ? 
ATOM   2036 C CG2 . VAL A 1 280 ? 16.432 -50.408 12.761  1.000 27.251  0 284 VAL A CG2 1 ? 
ATOM   2037 N N   . THR A 1 281 ? 14.053 -50.986 8.628   1.000 25.466  0 285 THR A N   1 ? 
ATOM   2038 C CA  . THR A 1 281 ? 13.945 -51.467 7.255   1.000 31.285  0 285 THR A CA  1 ? 
ATOM   2039 C C   . THR A 1 281 ? 15.091 -50.912 6.423   1.000 35.533  0 285 THR A C   1 ? 
ATOM   2040 O O   . THR A 1 281 ? 15.356 -49.698 6.411   1.000 29.114  0 285 THR A O   1 ? 
ATOM   2041 C CB  . THR A 1 281 ? 12.594 -51.102 6.629   1.000 34.399  0 285 THR A CB  1 ? 
ATOM   2042 O OG1 . THR A 1 281 ? 12.424 -49.683 6.632   1.000 33.351  0 285 THR A OG1 1 ? 
ATOM   2043 C CG2 . THR A 1 281 ? 11.476 -51.734 7.416   1.000 22.645  0 285 THR A CG2 1 ? 
ATOM   2044 N N   . ALA A 1 282 ? 15.780 -51.813 5.743   1.000 30.956  0 286 ALA A N   1 ? 
ATOM   2045 C CA  . ALA A 1 282 ? 16.983 -51.450 5.016   1.000 22.745  0 286 ALA A CA  1 ? 
ATOM   2046 C C   . ALA A 1 282 ? 17.040 -52.197 3.692   1.000 26.964  0 286 ALA A C   1 ? 
ATOM   2047 O O   . ALA A 1 282 ? 18.126 -52.498 3.193   1.000 27.543  0 286 ALA A O   1 ? 
ATOM   2048 C CB  . ALA A 1 282 ? 18.227 -51.724 5.872   1.000 22.642  0 286 ALA A CB  1 ? 
ATOM   2049 N N   . THR A 1 283 ? 15.871 -52.474 3.102   1.000 34.752  0 287 THR A N   1 ? 
ATOM   2050 C CA  . THR A 1 283 ? 15.745 -53.374 1.961   1.000 33.078  0 287 THR A CA  1 ? 
ATOM   2051 C C   . THR A 1 283 ? 15.772 -52.657 0.629   1.000 25.216  0 287 THR A C   1 ? 
ATOM   2052 O O   . THR A 1 283 ? 16.014 -53.295 -0.397  1.000 29.990  0 287 THR A O   1 ? 
ATOM   2053 C CB  . THR A 1 283 ? 14.429 -54.157 2.039   1.000 34.725  0 287 THR A CB  1 ? 
ATOM   2054 O OG1 . THR A 1 283 ? 13.334 -53.245 1.862   1.000 36.239  0 287 THR A OG1 1 ? 
ATOM   2055 C CG2 . THR A 1 283 ? 14.273 -54.869 3.386   1.000 22.513  0 287 THR A CG2 1 ? 
ATOM   2056 N N   . GLY A 1 284 ? 15.507 -51.356 0.616   1.000 27.869  0 288 GLY A N   1 ? 
ATOM   2057 C CA  . GLY A 1 284 ? 15.278 -50.661 -0.633  1.000 25.385  0 288 GLY A CA  1 ? 
ATOM   2058 C C   . GLY A 1 284 ? 14.070 -51.152 -1.394  1.000 34.499  0 288 GLY A C   1 ? 
ATOM   2059 O O   . GLY A 1 284 ? 13.981 -50.918 -2.606  1.000 32.122  0 288 GLY A O   1 ? 
ATOM   2060 N N   . ASN A 1 285 ? 13.126 -51.814 -0.711  1.000 29.464  0 289 ASN A N   1 ? 
ATOM   2061 C CA  . ASN A 1 285 ? 12.023 -52.533 -1.339  1.000 29.488  0 289 ASN A CA  1 ? 
ATOM   2062 C C   . ASN A 1 285 ? 10.666 -51.974 -0.866  1.000 29.419  0 289 ASN A C   1 ? 
ATOM   2063 O O   . ASN A 1 285 ? 10.579 -50.990 -0.124  1.000 32.793  0 289 ASN A O   1 ? 
ATOM   2064 C CB  . ASN A 1 285 ? 12.166 -54.035 -1.053  1.000 32.857  0 289 ASN A CB  1 ? 
ATOM   2065 C CG  . ASN A 1 285 ? 11.518 -54.926 -2.125  1.000 38.470  0 289 ASN A CG  1 ? 
ATOM   2066 O OD1 . ASN A 1 285 ? 10.493 -54.577 -2.747  1.000 39.486  0 289 ASN A OD1 1 ? 
ATOM   2067 N ND2 . ASN A 1 285 ? 12.126 -56.092 -2.347  1.000 30.372  0 289 ASN A ND2 1 ? 
ATOM   2068 N N   . TYR A 1 286 ? 9.601  -52.625 -1.304  1.000 25.427  0 290 TYR A N   1 ? 
ATOM   2069 C CA  . TYR A 1 286 ? 8.247  -52.115 -1.173  1.000 33.041  0 290 TYR A CA  1 ? 
ATOM   2070 C C   . TYR A 1 286 ? 7.455  -52.973 -0.189  1.000 35.725  0 290 TYR A C   1 ? 
ATOM   2071 O O   . TYR A 1 286 ? 7.378  -54.197 -0.357  1.000 34.425  0 290 TYR A O   1 ? 
ATOM   2072 C CB  . TYR A 1 286 ? 7.565  -52.092 -2.540  1.000 37.970  0 290 TYR A CB  1 ? 
ATOM   2073 C CG  . TYR A 1 286 ? 6.178  -51.494 -2.544  1.000 36.502  0 290 TYR A CG  1 ? 
ATOM   2074 C CD1 . TYR A 1 286 ? 6.005  -50.124 -2.655  1.000 34.502  0 290 TYR A CD1 1 ? 
ATOM   2075 C CD2 . TYR A 1 286 ? 5.045  -52.296 -2.450  1.000 38.647  0 290 TYR A CD2 1 ? 
ATOM   2076 C CE1 . TYR A 1 286 ? 4.747  -49.561 -2.674  1.000 40.160  0 290 TYR A CE1 1 ? 
ATOM   2077 C CE2 . TYR A 1 286 ? 3.766  -51.734 -2.475  1.000 44.834  0 290 TYR A CE2 1 ? 
ATOM   2078 C CZ  . TYR A 1 286 ? 3.638  -50.361 -2.583  1.000 42.739  0 290 TYR A CZ  1 ? 
ATOM   2079 O OH  . TYR A 1 286 ? 2.416  -49.767 -2.590  1.000 42.347  0 290 TYR A OH  1 ? 
ATOM   2080 N N   . HIS A 1 287 ? 6.896  -52.320 0.847   1.000 29.088  0 291 HIS A N   1 ? 
ATOM   2081 C CA  . HIS A 1 287 ? 5.931  -52.917 1.774   1.000 35.331  0 291 HIS A CA  1 ? 
ATOM   2082 C C   . HIS A 1 287 ? 6.507  -54.149 2.465   1.000 32.017  0 291 HIS A C   1 ? 
ATOM   2083 O O   . HIS A 1 287 ? 5.840  -55.172 2.615   1.000 38.589  0 291 HIS A O   1 ? 
ATOM   2084 C CB  . HIS A 1 287 ? 4.608  -53.261 1.073   1.000 40.207  0 291 HIS A CB  1 ? 
ATOM   2085 C CG  . HIS A 1 287 ? 3.710  -52.083 0.848   1.000 40.671  0 291 HIS A CG  1 ? 
ATOM   2086 N ND1 . HIS A 1 287 ? 4.145  -50.778 0.951   1.000 43.245  0 291 HIS A ND1 1 ? 
ATOM   2087 C CD2 . HIS A 1 287 ? 2.400  -52.015 0.516   1.000 40.386  0 291 HIS A CD2 1 ? 
ATOM   2088 C CE1 . HIS A 1 287 ? 3.144  -49.955 0.693   1.000 33.946  0 291 HIS A CE1 1 ? 
ATOM   2089 N NE2 . HIS A 1 287 ? 2.074  -50.682 0.429   1.000 44.190  0 291 HIS A NE2 1 ? 
ATOM   2090 N N   . VAL A 1 288 ? 7.756  -54.052 2.904   1.000 26.682  0 292 VAL A N   1 ? 
ATOM   2091 C CA  . VAL A 1 288 ? 8.328  -55.154 3.670   1.000 26.353  0 292 VAL A CA  1 ? 
ATOM   2092 C C   . VAL A 1 288 ? 7.819  -55.175 5.111   1.000 24.342  0 292 VAL A C   1 ? 
ATOM   2093 O O   . VAL A 1 288 ? 7.966  -56.195 5.791   1.000 38.594  0 292 VAL A O   1 ? 
ATOM   2094 C CB  . VAL A 1 288 ? 9.868  -55.104 3.591   1.000 30.467  0 292 VAL A CB  1 ? 
ATOM   2095 C CG1 . VAL A 1 288 ? 10.308 -54.994 2.132   1.000 24.269  0 292 VAL A CG1 1 ? 
ATOM   2096 C CG2 . VAL A 1 288 ? 10.421 -53.933 4.391   1.000 37.610  0 292 VAL A CG2 1 ? 
ATOM   2097 N N   . VAL A 1 289 ? 7.237  -54.085 5.600   1.000 24.479  0 293 VAL A N   1 ? 
ATOM   2098 C CA  . VAL A 1 289 ? 6.509  -54.071 6.863   1.000 32.780  0 293 VAL A CA  1 ? 
ATOM   2099 C C   . VAL A 1 289 ? 5.048  -53.794 6.535   1.000 34.846  0 293 VAL A C   1 ? 
ATOM   2100 O O   . VAL A 1 289 ? 4.711  -52.709 6.045   1.000 40.552  0 293 VAL A O   1 ? 
ATOM   2101 C CB  . VAL A 1 289 ? 7.052  -53.028 7.852   1.000 39.728  0 293 VAL A CB  1 ? 
ATOM   2102 C CG1 . VAL A 1 289 ? 6.130  -52.940 9.075   1.000 34.073  0 293 VAL A CG1 1 ? 
ATOM   2103 C CG2 . VAL A 1 289 ? 8.466  -53.377 8.292   1.000 42.066  0 293 VAL A CG2 1 ? 
ATOM   2104 N N   . THR A 1 290 ? 4.177  -54.760 6.814   1.000 35.031  0 294 THR A N   1 ? 
ATOM   2105 C CA  . THR A 1 290 ? 2.765  -54.663 6.457   1.000 36.299  0 294 THR A CA  1 ? 
ATOM   2106 C C   . THR A 1 290 ? 1.884  -54.297 7.650   1.000 39.818  0 294 THR A C   1 ? 
ATOM   2107 O O   . THR A 1 290 ? 2.310  -54.222 8.809   1.000 41.868  0 294 THR A O   1 ? 
ATOM   2108 C CB  . THR A 1 290 ? 2.255  -55.976 5.859   1.000 31.327  0 294 THR A CB  1 ? 
ATOM   2109 O OG1 . THR A 1 290 ? 2.206  -56.982 6.885   1.000 36.552  0 294 THR A OG1 1 ? 
ATOM   2110 C CG2 . THR A 1 290 ? 3.156  -56.432 4.753   1.000 28.456  0 294 THR A CG2 1 ? 
ATOM   2111 N N   . HIS A 1 291 ? 0.611  -54.091 7.331   1.000 38.131  0 295 HIS A N   1 ? 
ATOM   2112 C CA  . HIS A 1 291 ? -0.375 -53.808 8.359   1.000 34.849  0 295 HIS A CA  1 ? 
ATOM   2113 C C   . HIS A 1 291 ? -0.478 -54.930 9.376   1.000 34.336  0 295 HIS A C   1 ? 
ATOM   2114 O O   . HIS A 1 291 ? -0.620 -54.672 10.578  1.000 37.173  0 295 HIS A O   1 ? 
ATOM   2115 C CB  . HIS A 1 291 ? -1.741 -53.587 7.749   1.000 29.246  0 295 HIS A CB  1 ? 
ATOM   2116 C CG  . HIS A 1 291 ? -2.775 -53.324 8.781   1.000 31.333  0 295 HIS A CG  1 ? 
ATOM   2117 N ND1 . HIS A 1 291 ? -3.485 -54.335 9.398   1.000 35.454  0 295 HIS A ND1 1 ? 
ATOM   2118 C CD2 . HIS A 1 291 ? -3.161 -52.172 9.374   1.000 35.133  0 295 HIS A CD2 1 ? 
ATOM   2119 C CE1 . HIS A 1 291 ? -4.301 -53.808 10.291  1.000 38.484  0 295 HIS A CE1 1 ? 
ATOM   2120 N NE2 . HIS A 1 291 ? -4.129 -52.496 10.291  1.000 37.705  0 295 HIS A NE2 1 ? 
ATOM   2121 N N   . ASP A 1 292 ? -0.479 -56.182 8.916   1.000 29.325  0 296 ASP A N   1 ? 
ATOM   2122 C CA  . ASP A 1 292 ? -0.593 -57.285 9.862   1.000 36.044  0 296 ASP A CA  1 ? 
ATOM   2123 C C   . ASP A 1 292 ? 0.631  -57.353 10.774  1.000 41.900  0 296 ASP A C   1 ? 
ATOM   2124 O O   . ASP A 1 292 ? 0.510  -57.648 11.973  1.000 36.102  0 296 ASP A O   1 ? 
ATOM   2125 C CB  . ASP A 1 292 ? -0.809 -58.605 9.123   1.000 35.433  0 296 ASP A CB  1 ? 
ATOM   2126 C CG  . ASP A 1 292 ? -1.509 -59.652 9.991   1.000 39.689  0 296 ASP A CG  1 ? 
ATOM   2127 O OD1 . ASP A 1 292 ? -2.531 -59.334 10.643  1.000 40.234  0 296 ASP A OD1 1 ? 
ATOM   2128 O OD2 . ASP A 1 292 ? -1.028 -60.801 10.037  1.000 40.958  0 296 ASP A OD2 1 ? 
ATOM   2129 N N   . HIS A 1 293 ? 1.812  -57.036 10.235  1.000 37.526  0 297 HIS A N   1 ? 
ATOM   2130 C CA  . HIS A 1 293 ? 3.015  -56.991 11.061  1.000 32.686  0 297 HIS A CA  1 ? 
ATOM   2131 C C   . HIS A 1 293 ? 2.859  -55.961 12.171  1.000 31.851  0 297 HIS A C   1 ? 
ATOM   2132 O O   . HIS A 1 293 ? 3.062  -56.256 13.355  1.000 31.370  0 297 HIS A O   1 ? 
ATOM   2133 C CB  . HIS A 1 293 ? 4.234  -56.662 10.197  1.000 29.535  0 297 HIS A CB  1 ? 
ATOM   2134 C CG  . HIS A 1 293 ? 4.613  -57.741 9.229   1.000 33.180  0 297 HIS A CG  1 ? 
ATOM   2135 N ND1 . HIS A 1 293 ? 5.203  -57.472 8.012   1.000 30.469  0 297 HIS A ND1 1 ? 
ATOM   2136 C CD2 . HIS A 1 293 ? 4.502  -59.092 9.304   1.000 31.543  0 297 HIS A CD2 1 ? 
ATOM   2137 C CE1 . HIS A 1 293 ? 5.450  -58.611 7.387   1.000 31.399  0 297 HIS A CE1 1 ? 
ATOM   2138 N NE2 . HIS A 1 293 ? 5.040  -59.608 8.151   1.000 28.682  0 297 HIS A NE2 1 ? 
ATOM   2139 N N   . MET A 1 294 ? 2.480  -54.744 11.802  1.000 26.140  0 298 MET A N   1 ? 
ATOM   2140 C CA  . MET A 1 294 ? 2.399  -53.685 12.793  1.000 38.234  0 298 MET A CA  1 ? 
ATOM   2141 C C   . MET A 1 294 ? 1.293  -53.956 13.802  1.000 42.152  0 298 MET A C   1 ? 
ATOM   2142 O O   . MET A 1 294 ? 1.463  -53.672 14.992  1.000 39.721  0 298 MET A O   1 ? 
ATOM   2143 C CB  . MET A 1 294 ? 2.207  -52.344 12.090  1.000 31.401  0 298 MET A CB  1 ? 
ATOM   2144 C CG  . MET A 1 294 ? 3.345  -52.027 11.113  1.000 28.640  0 298 MET A CG  1 ? 
ATOM   2145 S SD  . MET A 1 294 ? 3.106  -50.462 10.268  1.000 41.544  0 298 MET A SD  1 ? 
ATOM   2146 C CE  . MET A 1 294 ? 2.483  -50.981 8.685   1.000 33.754  0 298 MET A CE  1 ? 
ATOM   2147 N N   . LYS A 1 295 ? 0.173  -54.536 13.359  1.000 41.473  0 299 LYS A N   1 ? 
ATOM   2148 C CA  . LYS A 1 295 ? -0.863 -54.938 14.302  1.000 37.678  0 299 LYS A CA  1 ? 
ATOM   2149 C C   . LYS A 1 295 ? -0.350 -55.991 15.279  1.000 36.554  0 299 LYS A C   1 ? 
ATOM   2150 O O   . LYS A 1 295 ? -0.722 -55.982 16.456  1.000 38.234  0 299 LYS A O   1 ? 
ATOM   2151 C CB  . LYS A 1 295 ? -2.092 -55.449 13.543  1.000 43.716  0 299 LYS A CB  1 ? 
ATOM   2152 C CG  . LYS A 1 295 ? -3.075 -56.247 14.390  1.000 41.676  0 299 LYS A CG  1 ? 
ATOM   2153 C CD  . LYS A 1 295 ? -4.301 -56.645 13.578  1.000 53.062  0 299 LYS A CD  1 ? 
ATOM   2154 C CE  . LYS A 1 295 ? -4.984 -57.901 14.126  1.000 55.025  0 299 LYS A CE  1 ? 
ATOM   2155 N NZ  . LYS A 1 295 ? -5.159 -58.901 13.030  1.000 55.109  0 299 LYS A NZ  1 ? 
ATOM   2156 N N   . ARG A 1 296 ? 0.518  -56.894 14.827  1.000 30.922  0 300 ARG A N   1 ? 
ATOM   2157 C CA  . ARG A 1 296 ? 1.066  -57.891 15.739  1.000 27.730  0 300 ARG A CA  1 ? 
ATOM   2158 C C   . ARG A 1 296 ? 2.169  -57.351 16.656  1.000 36.694  0 300 ARG A C   1 ? 
ATOM   2159 O O   . ARG A 1 296 ? 2.549  -58.035 17.607  1.000 35.917  0 300 ARG A O   1 ? 
ATOM   2160 C CB  . ARG A 1 296 ? 1.618  -59.068 14.939  1.000 27.351  0 300 ARG A CB  1 ? 
ATOM   2161 C CG  . ARG A 1 296 ? 0.610  -59.746 14.034  1.000 28.222  0 300 ARG A CG  1 ? 
ATOM   2162 C CD  . ARG A 1 296 ? 0.966  -61.199 13.873  1.000 28.446  0 300 ARG A CD  1 ? 
ATOM   2163 N NE  . ARG A 1 296 ? 1.768  -61.429 12.686  1.000 28.001  0 300 ARG A NE  1 ? 
ATOM   2164 C CZ  . ARG A 1 296 ? 2.883  -62.155 12.641  1.000 27.535  0 300 ARG A CZ  1 ? 
ATOM   2165 N NH1 . ARG A 1 296 ? 3.376  -62.733 13.726  1.000 27.422  0 300 ARG A NH1 1 ? 
ATOM   2166 N NH2 . ARG A 1 296 ? 3.505  -62.291 11.480  1.000 33.872  0 300 ARG A NH2 1 ? 
ATOM   2167 N N   . MET A 1 297 ? 2.707  -56.170 16.396  1.000 26.045  0 301 MET A N   1 ? 
ATOM   2168 C CA  . MET A 1 297 ? 3.854  -55.716 17.154  1.000 27.372  0 301 MET A CA  1 ? 
ATOM   2169 C C   . MET A 1 297 ? 3.449  -55.327 18.562  1.000 32.722  0 301 MET A C   1 ? 
ATOM   2170 O O   . MET A 1 297 ? 2.312  -54.935 18.817  1.000 33.646  0 301 MET A O   1 ? 
ATOM   2171 C CB  . MET A 1 297 ? 4.520  -54.532 16.475  1.000 24.792  0 301 MET A CB  1 ? 
ATOM   2172 C CG  . MET A 1 297 ? 5.560  -54.931 15.499  1.000 24.287  0 301 MET A CG  1 ? 
ATOM   2173 S SD  . MET A 1 297 ? 5.963  -53.510 14.494  1.000 32.491  0 301 MET A SD  1 ? 
ATOM   2174 C CE  . MET A 1 297 ? 6.522  -54.320 12.995  1.000 31.551  0 301 MET A CE  1 ? 
ATOM   2175 N N   . ARG A 1 298 ? 4.401  -55.432 19.481  1.000 35.699  0 302 ARG A N   1 ? 
ATOM   2176 C CA  . ARG A 1 298 ? 4.108  -55.098 20.863  1.000 29.796  0 302 ARG A CA  1 ? 
ATOM   2177 C C   . ARG A 1 298 ? 3.905  -53.594 21.029  1.000 36.270  0 302 ARG A C   1 ? 
ATOM   2178 O O   . ARG A 1 298 ? 4.416  -52.771 20.260  1.000 32.875  0 302 ARG A O   1 ? 
ATOM   2179 C CB  . ARG A 1 298 ? 5.233  -55.581 21.772  1.000 28.846  0 302 ARG A CB  1 ? 
ATOM   2180 C CG  . ARG A 1 298 ? 6.646  -55.179 21.330  1.000 30.327  0 302 ARG A CG  1 ? 
ATOM   2181 C CD  . ARG A 1 298 ? 7.681  -55.802 22.267  1.000 43.079  0 302 ARG A CD  1 ? 
ATOM   2182 N NE  . ARG A 1 298 ? 7.798  -55.042 23.521  1.000 50.388  0 302 ARG A NE  1 ? 
ATOM   2183 C CZ  . ARG A 1 298 ? 7.470  -55.502 24.731  1.000 50.327  0 302 ARG A CZ  1 ? 
ATOM   2184 N NH1 . ARG A 1 298 ? 6.997  -56.736 24.891  1.000 47.437  0 302 ARG A NH1 1 ? 
ATOM   2185 N NH2 . ARG A 1 298 ? 7.612  -54.721 25.790  1.000 51.672  0 302 ARG A NH2 1 ? 
ATOM   2186 N N   . ASN A 1 299 ? 3.158  -53.244 22.071  1.000 38.497  0 303 ASN A N   1 ? 
ATOM   2187 C CA  . ASN A 1 299 ? 2.993  -51.850 22.460  1.000 35.954  0 303 ASN A CA  1 ? 
ATOM   2188 C C   . ASN A 1 299 ? 4.338  -51.133 22.619  1.000 35.857  0 303 ASN A C   1 ? 
ATOM   2189 O O   . ASN A 1 299 ? 5.272  -51.663 23.234  1.000 33.680  0 303 ASN A O   1 ? 
ATOM   2190 C CB  . ASN A 1 299 ? 2.205  -51.797 23.760  1.000 26.372  0 303 ASN A CB  1 ? 
ATOM   2191 C CG  . ASN A 1 299 ? 1.957  -50.398 24.226  1.000 26.537  0 303 ASN A CG  1 ? 
ATOM   2192 O OD1 . ASN A 1 299 ? 1.348  -49.590 23.518  1.000 38.091  0 303 ASN A OD1 1 ? 
ATOM   2193 N ND2 . ASN A 1 299 ? 2.429  -50.088 25.436  1.000 28.411  0 303 ASN A ND2 1 ? 
ATOM   2194 N N   . GLN A 1 300 ? 4.421  -49.916 22.053  1.000 36.702  0 304 GLN A N   1 ? 
ATOM   2195 C CA  . GLN A 1 300 ? 5.608  -49.054 22.050  1.000 36.002  0 304 GLN A CA  1 ? 
ATOM   2196 C C   . GLN A 1 300 ? 6.772  -49.635 21.251  1.000 34.075  0 304 GLN A C   1 ? 
ATOM   2197 O O   . GLN A 1 300 ? 7.914  -49.249 21.461  1.000 32.435  0 304 GLN A O   1 ? 
ATOM   2198 C CB  . GLN A 1 300 ? 6.097  -48.724 23.471  1.000 33.944  0 304 GLN A CB  1 ? 
ATOM   2199 C CG  . GLN A 1 300 ? 5.058  -48.113 24.384  1.000 30.654  0 304 GLN A CG  1 ? 
ATOM   2200 C CD  . GLN A 1 300 ? 4.655  -46.719 23.959  1.000 37.984  0 304 GLN A CD  1 ? 
ATOM   2201 O OE1 . GLN A 1 300 ? 5.201  -46.159 23.005  1.000 39.326  0 304 GLN A OE1 1 ? 
ATOM   2202 N NE2 . GLN A 1 300 ? 3.685  -46.148 24.663  1.000 40.389  0 304 GLN A NE2 1 ? 
ATOM   2203 N N   . ALA A 1 301 ? 6.516  -50.588 20.367  1.000 36.249  0 305 ALA A N   1 ? 
ATOM   2204 C CA  . ALA A 1 301 ? 7.536  -50.999 19.421  1.000 26.774  0 305 ALA A CA  1 ? 
ATOM   2205 C C   . ALA A 1 301 ? 7.948  -49.799 18.583  1.000 29.219  0 305 ALA A C   1 ? 
ATOM   2206 O O   . ALA A 1 301 ? 7.118  -48.971 18.201  1.000 32.899  0 305 ALA A O   1 ? 
ATOM   2207 C CB  . ALA A 1 301 ? 7.009  -52.118 18.523  1.000 23.466  0 305 ALA A CB  1 ? 
ATOM   2208 N N   . ILE A 1 302 ? 9.241  -49.686 18.335  1.000 33.096  0 306 ILE A N   1 ? 
ATOM   2209 C CA  . ILE A 1 302 ? 9.796  -48.595 17.556  1.000 35.220  0 306 ILE A CA  1 ? 
ATOM   2210 C C   . ILE A 1 302 ? 9.991  -49.109 16.145  1.000 34.573  0 306 ILE A C   1 ? 
ATOM   2211 O O   . ILE A 1 302 ? 10.630 -50.147 15.937  1.000 28.888  0 306 ILE A O   1 ? 
ATOM   2212 C CB  . ILE A 1 302 ? 11.121 -48.090 18.155  1.000 26.772  0 306 ILE A CB  1 ? 
ATOM   2213 C CG1 . ILE A 1 302 ? 10.850 -47.331 19.447  1.000 24.995  0 306 ILE A CG1 1 ? 
ATOM   2214 C CG2 . ILE A 1 302 ? 11.832 -47.198 17.183  1.000 22.216  0 306 ILE A CG2 1 ? 
ATOM   2215 C CD1 . ILE A 1 302 ? 11.995 -47.382 20.436  1.000 24.900  0 306 ILE A CD1 1 ? 
ATOM   2216 N N   . LEU A 1 303 ? 9.434  -48.399 15.179  1.000 27.427  0 307 LEU A N   1 ? 
ATOM   2217 C CA  . LEU A 1 303 ? 9.550  -48.776 13.786  1.000 24.374  0 307 LEU A CA  1 ? 
ATOM   2218 C C   . LEU A 1 303 ? 10.194 -47.630 13.018  1.000 30.835  0 307 LEU A C   1 ? 
ATOM   2219 O O   . LEU A 1 303 ? 9.727  -46.486 13.096  1.000 33.246  0 307 LEU A O   1 ? 
ATOM   2220 C CB  . LEU A 1 303 ? 8.170  -49.126 13.244  1.000 30.254  0 307 LEU A CB  1 ? 
ATOM   2221 C CG  . LEU A 1 303 ? 7.963  -49.354 11.761  1.000 36.775  0 307 LEU A CG  1 ? 
ATOM   2222 C CD1 . LEU A 1 303 ? 8.501  -50.710 11.382  1.000 44.613  0 307 LEU A CD1 1 ? 
ATOM   2223 C CD2 . LEU A 1 303 ? 6.482  -49.279 11.500  1.000 38.973  0 307 LEU A CD2 1 ? 
ATOM   2224 N N   . CYS A 1 304 ? 11.275 -47.922 12.294  1.000 28.140  0 308 CYS A N   1 ? 
ATOM   2225 C CA  . CYS A 1 304 ? 11.898 -46.869 11.503  1.000 35.665  0 308 CYS A CA  1 ? 
ATOM   2226 C C   . CYS A 1 304 ? 12.450 -47.430 10.205  1.000 31.899  0 308 CYS A C   1 ? 
ATOM   2227 O O   . CYS A 1 304 ? 12.719 -48.623 10.084  1.000 40.200  0 308 CYS A O   1 ? 
ATOM   2228 C CB  . CYS A 1 304 ? 13.009 -46.159 12.282  1.000 41.802  0 308 CYS A CB  1 ? 
ATOM   2229 S SG  . CYS A 1 304 ? 14.450 -47.181 12.514  1.000 45.269  0 308 CYS A SG  1 ? 
ATOM   2230 N N   . ASN A 1 305 ? 12.627 -46.536 9.236   1.000 33.154  0 309 ASN A N   1 ? 
ATOM   2231 C CA  . ASN A 1 305 ? 13.121 -46.867 7.905   1.000 28.003  0 309 ASN A CA  1 ? 
ATOM   2232 C C   . ASN A 1 305 ? 14.453 -46.161 7.655   1.000 37.844  0 309 ASN A C   1 ? 
ATOM   2233 O O   . ASN A 1 305 ? 14.541 -44.934 7.760   1.000 33.830  0 309 ASN A O   1 ? 
ATOM   2234 C CB  . ASN A 1 305 ? 12.102 -46.459 6.848   1.000 23.640  0 309 ASN A CB  1 ? 
ATOM   2235 C CG  . ASN A 1 305 ? 12.647 -46.573 5.436   1.000 31.522  0 309 ASN A CG  1 ? 
ATOM   2236 O OD1 . ASN A 1 305 ? 13.305 -47.552 5.082   1.000 30.309  0 309 ASN A OD1 1 ? 
ATOM   2237 N ND2 . ASN A 1 305 ? 12.380 -45.564 4.619   1.000 33.004  0 309 ASN A ND2 1 ? 
ATOM   2238 N N   . ILE A 1 306 ? 15.489 -46.929 7.318   1.000 36.612  0 310 ILE A N   1 ? 
ATOM   2239 C CA  . ILE A 1 306 ? 16.761 -46.361 6.903   1.000 26.872  0 310 ILE A CA  1 ? 
ATOM   2240 C C   . ILE A 1 306 ? 17.031 -46.589 5.423   1.000 27.235  0 310 ILE A C   1 ? 
ATOM   2241 O O   . ILE A 1 306 ? 18.040 -46.106 4.909   1.000 40.276  0 310 ILE A O   1 ? 
ATOM   2242 C CB  . ILE A 1 306 ? 17.923 -46.892 7.775   1.000 35.294  0 310 ILE A CB  1 ? 
ATOM   2243 C CG1 . ILE A 1 306 ? 19.126 -45.927 7.756   1.000 32.491  0 310 ILE A CG1 1 ? 
ATOM   2244 C CG2 . ILE A 1 306 ? 18.329 -48.325 7.359   1.000 21.918  0 310 ILE A CG2 1 ? 
ATOM   2245 C CD1 . ILE A 1 306 ? 20.021 -45.964 9.005   1.000 29.356  0 310 ILE A CD1 1 ? 
ATOM   2246 N N   . GLY A 1 307 ? 16.172 -47.322 4.725   1.000 35.249  0 311 GLY A N   1 ? 
ATOM   2247 C CA  . GLY A 1 307 ? 16.240 -47.375 3.278   1.000 26.822  0 311 GLY A CA  1 ? 
ATOM   2248 C C   . GLY A 1 307 ? 15.813 -46.052 2.677   1.000 34.973  0 311 GLY A C   1 ? 
ATOM   2249 O O   . GLY A 1 307 ? 15.298 -45.166 3.357   1.000 42.700  0 311 GLY A O   1 ? 
ATOM   2250 N N   . HIS A 1 308 ? 16.019 -45.911 1.366   1.000 36.057  0 312 HIS A N   1 ? 
ATOM   2251 C CA  . HIS A 1 308 ? 15.905 -44.579 0.773   1.000 40.013  0 312 HIS A CA  1 ? 
ATOM   2252 C C   . HIS A 1 308 ? 14.473 -44.047 0.784   1.000 50.224  0 312 HIS A C   1 ? 
ATOM   2253 O O   . HIS A 1 308 ? 14.256 -42.844 0.983   1.000 43.131  0 312 HIS A O   1 ? 
ATOM   2254 C CB  . HIS A 1 308 ? 16.435 -44.579 -0.651  1.000 37.423  0 312 HIS A CB  1 ? 
ATOM   2255 C CG  . HIS A 1 308 ? 16.513 -43.209 -1.249  1.000 45.116  0 312 HIS A CG  1 ? 
ATOM   2256 N ND1 . HIS A 1 308 ? 17.516 -42.313 -0.935  1.000 42.031  0 312 HIS A ND1 1 ? 
ATOM   2257 C CD2 . HIS A 1 308 ? 15.696 -42.571 -2.119  1.000 43.524  0 312 HIS A CD2 1 ? 
ATOM   2258 C CE1 . HIS A 1 308 ? 17.320 -41.188 -1.594  1.000 43.542  0 312 HIS A CE1 1 ? 
ATOM   2259 N NE2 . HIS A 1 308 ? 16.224 -41.320 -2.325  1.000 47.979  0 312 HIS A NE2 1 ? 
ATOM   2260 N N   . PHE A 1 309 ? 13.487 -44.910 0.552   1.000 54.757  0 313 PHE A N   1 ? 
ATOM   2261 C CA  . PHE A 1 309 ? 12.122 -44.468 0.312   1.000 58.662  0 313 PHE A CA  1 ? 
ATOM   2262 C C   . PHE A 1 309 ? 11.201 -44.964 1.415   1.000 55.143  0 313 PHE A C   1 ? 
ATOM   2263 O O   . PHE A 1 309 ? 11.451 -46.004 2.029   1.000 52.725  0 313 PHE A O   1 ? 
ATOM   2264 C CB  . PHE A 1 309 ? 11.619 -44.961 -1.048  1.000 56.238  0 313 PHE A CB  1 ? 
ATOM   2265 C CG  . PHE A 1 309 ? 12.029 -44.089 -2.198  1.000 52.359  0 313 PHE A CG  1 ? 
ATOM   2266 C CD1 . PHE A 1 309 ? 11.864 -42.706 -2.135  1.000 45.837  0 313 PHE A CD1 1 ? 
ATOM   2267 C CD2 . PHE A 1 309 ? 12.582 -44.647 -3.346  1.000 49.914  0 313 PHE A CD2 1 ? 
ATOM   2268 C CE1 . PHE A 1 309 ? 12.230 -41.887 -3.213  1.000 40.068  0 313 PHE A CE1 1 ? 
ATOM   2269 C CE2 . PHE A 1 309 ? 12.948 -43.841 -4.432  1.000 41.734  0 313 PHE A CE2 1 ? 
ATOM   2270 C CZ  . PHE A 1 309 ? 12.773 -42.456 -4.366  1.000 35.265  0 313 PHE A CZ  1 ? 
ATOM   2271 N N   . ASP A 1 310 ? 10.127 -44.203 1.655   1.000 57.573  0 314 ASP A N   1 ? 
ATOM   2272 C CA  . ASP A 1 310 ? 9.133  -44.566 2.669   1.000 62.747  0 314 ASP A CA  1 ? 
ATOM   2273 C C   . ASP A 1 310 ? 8.377  -45.849 2.312   1.000 54.449  0 314 ASP A C   1 ? 
ATOM   2274 O O   . ASP A 1 310 ? 7.921  -46.568 3.208   1.000 55.544  0 314 ASP A O   1 ? 
ATOM   2275 C CB  . ASP A 1 310 ? 8.157  -43.413 2.840   1.000 64.666  0 314 ASP A CB  1 ? 
ATOM   2276 C CG  . ASP A 1 310 ? 7.856  -42.738 1.532   1.000 75.506  0 314 ASP A CG  1 ? 
ATOM   2277 O OD1 . ASP A 1 310 ? 7.635  -43.452 0.528   1.000 82.023  0 314 ASP A OD1 1 ? 
ATOM   2278 O OD2 . ASP A 1 310 ? 7.877  -41.497 1.490   1.000 82.089  0 314 ASP A OD2 1 ? 
ATOM   2279 N N   . SER A 1 311 ? 8.233  -46.138 1.019   1.000 44.445  0 315 SER A N   1 ? 
ATOM   2280 C CA  . SER A 1 311 ? 7.673  -47.364 0.467   1.000 43.160  0 315 SER A CA  1 ? 
ATOM   2281 C C   . SER A 1 311 ? 7.881  -48.621 1.314   1.000 42.284  0 315 SER A C   1 ? 
ATOM   2282 O O   . SER A 1 311 ? 7.094  -49.562 1.226   1.000 52.283  0 315 SER A O   1 ? 
ATOM   2283 C CB  . SER A 1 311 ? 8.277  -47.588 -0.921  1.000 53.485  0 315 SER A CB  1 ? 
ATOM   2284 O OG  . SER A 1 311 ? 9.702  -47.727 -0.844  1.000 60.807  0 315 SER A OG  1 ? 
ATOM   2285 N N   . GLU A 1 312 ? 8.929  -48.664 2.132   1.000 38.899  0 316 GLU A N   1 ? 
ATOM   2286 C CA  . GLU A 1 312 ? 9.288  -49.911 2.806   1.000 31.764  0 316 GLU A CA  1 ? 
ATOM   2287 C C   . GLU A 1 312 ? 8.257  -50.320 3.842   1.000 28.914  0 316 GLU A C   1 ? 
ATOM   2288 O O   . GLU A 1 312 ? 8.038  -51.519 4.046   1.000 30.912  0 316 GLU A O   1 ? 
ATOM   2289 C CB  . GLU A 1 312 ? 10.667 -49.788 3.444   1.000 24.063  0 316 GLU A CB  1 ? 
ATOM   2290 C CG  . GLU A 1 312 ? 11.716 -49.398 2.441   1.000 31.017  0 316 GLU A CG  1 ? 
ATOM   2291 C CD  . GLU A 1 312 ? 13.084 -50.015 2.698   1.000 39.763  0 316 GLU A CD  1 ? 
ATOM   2292 O OE1 . GLU A 1 312 ? 14.049 -49.507 2.099   1.000 36.428  0 316 GLU A OE1 1 ? 
ATOM   2293 O OE2 . GLU A 1 312 ? 13.198 -51.000 3.469   1.000 40.815  0 316 GLU A OE2 1 ? 
ATOM   2294 N N   . ILE A 1 313 ? 7.626  -49.352 4.505   1.000 30.162  0 317 ILE A N   1 ? 
ATOM   2295 C CA  . ILE A 1 313 ? 6.514  -49.606 5.413   1.000 33.901  0 317 ILE A CA  1 ? 
ATOM   2296 C C   . ILE A 1 313 ? 5.223  -49.150 4.744   1.000 36.052  0 317 ILE A C   1 ? 
ATOM   2297 O O   . ILE A 1 313 ? 5.207  -48.195 3.960   1.000 37.741  0 317 ILE A O   1 ? 
ATOM   2298 C CB  . ILE A 1 313 ? 6.744  -48.893 6.759   1.000 36.610  0 317 ILE A CB  1 ? 
ATOM   2299 C CG1 . ILE A 1 313 ? 8.102  -49.302 7.330   1.000 28.688  0 317 ILE A CG1 1 ? 
ATOM   2300 C CG2 . ILE A 1 313 ? 5.619  -49.201 7.745   1.000 35.741  0 317 ILE A CG2 1 ? 
ATOM   2301 C CD1 . ILE A 1 313 ? 8.762  -48.241 8.200   1.000 25.627  0 317 ILE A CD1 1 ? 
ATOM   2302 N N   . ASP A 1 314 ? 4.137  -49.870 5.021   1.000 42.268  0 318 ASP A N   1 ? 
ATOM   2303 C CA  . ASP A 1 314 ? 2.825  -49.518 4.468   1.000 38.376  0 318 ASP A CA  1 ? 
ATOM   2304 C C   . ASP A 1 314 ? 2.158  -48.540 5.428   1.000 38.055  0 318 ASP A C   1 ? 
ATOM   2305 O O   . ASP A 1 314 ? 1.286  -48.889 6.226   1.000 37.755  0 318 ASP A O   1 ? 
ATOM   2306 C CB  . ASP A 1 314 ? 1.970  -50.757 4.250   1.000 33.257  0 318 ASP A CB  1 ? 
ATOM   2307 C CG  . ASP A 1 314 ? 0.644  -50.445 3.541   1.000 42.750  0 318 ASP A CG  1 ? 
ATOM   2308 O OD1 . ASP A 1 314 ? 0.386  -49.278 3.157   1.000 38.257  0 318 ASP A OD1 1 ? 
ATOM   2309 O OD2 . ASP A 1 314 ? -0.151 -51.390 3.373   1.000 46.869  0 318 ASP A OD2 1 ? 
ATOM   2310 N N   . ILE A 1 315 ? 2.600  -47.288 5.348   1.000 32.033  0 319 ILE A N   1 ? 
ATOM   2311 C CA  . ILE A 1 315 ? 2.037  -46.242 6.191   1.000 36.183  0 319 ILE A CA  1 ? 
ATOM   2312 C C   . ILE A 1 315 ? 0.588  -45.954 5.797   1.000 43.474  0 319 ILE A C   1 ? 
ATOM   2313 O O   . ILE A 1 315 ? -0.223 -45.554 6.641   1.000 46.274  0 319 ILE A O   1 ? 
ATOM   2314 C CB  . ILE A 1 315 ? 2.940  -44.993 6.100   1.000 40.744  0 319 ILE A CB  1 ? 
ATOM   2315 C CG1 . ILE A 1 315 ? 4.397  -45.366 6.426   1.000 30.962  0 319 ILE A CG1 1 ? 
ATOM   2316 C CG2 . ILE A 1 315 ? 2.445  -43.883 7.016   1.000 41.147  0 319 ILE A CG2 1 ? 
ATOM   2317 C CD1 . ILE A 1 315 ? 4.703  -45.394 7.939   1.000 32.443  0 319 ILE A CD1 1 ? 
ATOM   2318 N N   . GLN A 1 316 ? 0.230  -46.178 4.526   1.000 43.758  0 320 GLN A N   1 ? 
ATOM   2319 C CA  . GLN A 1 316 ? -1.163 -46.032 4.110   1.000 49.161  0 320 GLN A CA  1 ? 
ATOM   2320 C C   . GLN A 1 316 ? -2.082 -46.838 5.012   1.000 48.248  0 320 GLN A C   1 ? 
ATOM   2321 O O   . GLN A 1 316 ? -3.145 -46.359 5.423   1.000 45.198  0 320 GLN A O   1 ? 
ATOM   2322 C CB  . GLN A 1 316 ? -1.347 -46.474 2.656   1.000 56.294  0 320 GLN A CB  1 ? 
ATOM   2323 C CG  . GLN A 1 316 ? -1.011 -45.416 1.636   1.000 72.930  0 320 GLN A CG  1 ? 
ATOM   2324 C CD  . GLN A 1 316 ? 0.253  -44.659 1.997   1.000 88.897  0 320 GLN A CD  1 ? 
ATOM   2325 O OE1 . GLN A 1 316 ? 0.192  -43.500 2.417   1.000 98.962  0 320 GLN A OE1 1 ? 
ATOM   2326 N NE2 . GLN A 1 316 ? 1.408  -45.318 1.859   1.000 86.281  0 320 GLN A NE2 1 ? 
ATOM   2327 N N   . SER A 1 317 ? -1.673 -48.058 5.353   1.000 44.247  0 321 SER A N   1 ? 
ATOM   2328 C CA  . SER A 1 317 ? -2.499 -48.924 6.178   1.000 38.231  0 321 SER A CA  1 ? 
ATOM   2329 C C   . SER A 1 317 ? -2.631 -48.425 7.609   1.000 43.916  0 321 SER A C   1 ? 
ATOM   2330 O O   . SER A 1 317 ? -3.401 -49.021 8.372   1.000 43.624  0 321 SER A O   1 ? 
ATOM   2331 C CB  . SER A 1 317 ? -1.948 -50.350 6.153   1.000 33.504  0 321 SER A CB  1 ? 
ATOM   2332 O OG  . SER A 1 317 ? -0.857 -50.503 7.038   1.000 44.842  0 321 SER A OG  1 ? 
ATOM   2333 N N   . LEU A 1 318 ? -1.938 -47.342 7.977   1.000 40.197  0 322 LEU A N   1 ? 
ATOM   2334 C CA  . LEU A 1 318 ? -2.072 -46.729 9.294   1.000 37.404  0 322 LEU A CA  1 ? 
ATOM   2335 C C   . LEU A 1 318 ? -2.858 -45.432 9.266   1.000 41.602  0 322 LEU A C   1 ? 
ATOM   2336 O O   . LEU A 1 318 ? -3.001 -44.791 10.314  1.000 48.795  0 322 LEU A O   1 ? 
ATOM   2337 C CB  . LEU A 1 318 ? -0.692 -46.461 9.903   1.000 31.896  0 322 LEU A CB  1 ? 
ATOM   2338 C CG  . LEU A 1 318 ? 0.218  -47.672 9.852   1.000 30.085  0 322 LEU A CG  1 ? 
ATOM   2339 C CD1 . LEU A 1 318 ? 1.571  -47.270 10.369  1.000 36.260  0 322 LEU A CD1 1 ? 
ATOM   2340 C CD2 . LEU A 1 318 ? -0.376 -48.779 10.693  1.000 33.225  0 322 LEU A CD2 1 ? 
ATOM   2341 N N   . LYS A 1 319 ? -3.358 -45.022 8.099   1.000 49.190  0 323 LYS A N   1 ? 
ATOM   2342 C CA  . LYS A 1 319 ? -4.105 -43.774 8.021   1.000 57.125  0 323 LYS A CA  1 ? 
ATOM   2343 C C   . LYS A 1 319 ? -5.486 -43.899 8.649   1.000 63.010  0 323 LYS A C   1 ? 
ATOM   2344 O O   . LYS A 1 319 ? -6.049 -42.892 9.097   1.000 64.187  0 323 LYS A O   1 ? 
ATOM   2345 C CB  . LYS A 1 319 ? -4.228 -43.310 6.571   1.000 65.863  0 323 LYS A CB  1 ? 
ATOM   2346 C CG  . LYS A 1 319 ? -4.357 -41.803 6.467   1.000 77.088  0 323 LYS A CG  1 ? 
ATOM   2347 C CD  . LYS A 1 319 ? -4.814 -41.331 5.100   1.000 79.394  0 323 LYS A CD  1 ? 
ATOM   2348 C CE  . LYS A 1 319 ? -4.384 -42.254 3.994   1.000 76.912  0 323 LYS A CE  1 ? 
ATOM   2349 N NZ  . LYS A 1 319 ? -5.185 -41.951 2.775   1.000 76.401  0 323 LYS A NZ  1 ? 
ATOM   2350 N N   . GLN A 1 320 ? -6.045 -45.112 8.696   1.000 68.624  0 324 GLN A N   1 ? 
ATOM   2351 C CA  . GLN A 1 320 ? -7.306 -45.318 9.406   1.000 70.761  0 324 GLN A CA  1 ? 
ATOM   2352 C C   . GLN A 1 320 ? -7.182 -44.877 10.857  1.000 71.616  0 324 GLN A C   1 ? 
ATOM   2353 O O   . GLN A 1 320 ? -8.013 -44.114 11.370  1.000 70.240  0 324 GLN A O   1 ? 
ATOM   2354 C CB  . GLN A 1 320 ? -7.711 -46.792 9.325   1.000 69.719  0 324 GLN A CB  1 ? 
ATOM   2355 C CG  . GLN A 1 320 ? -6.542 -47.752 9.093   1.000 70.666  0 324 GLN A CG  1 ? 
ATOM   2356 C CD  . GLN A 1 320 ? -6.982 -49.213 8.956   1.000 67.953  0 324 GLN A CD  1 ? 
ATOM   2357 O OE1 . GLN A 1 320 ? -8.135 -49.556 9.233   1.000 61.271  0 324 GLN A OE1 1 ? 
ATOM   2358 N NE2 . GLN A 1 320 ? -6.051 -50.081 8.540   1.000 61.552  0 324 GLN A NE2 1 ? 
ATOM   2359 N N   . TYR A 1 321 ? -6.108 -45.310 11.509  1.000 62.847  0 325 TYR A N   1 ? 
ATOM   2360 C CA  . TYR A 1 321 ? -5.903 -45.126 12.927  1.000 47.524  0 325 TYR A CA  1 ? 
ATOM   2361 C C   . TYR A 1 321 ? -5.582 -43.677 13.272  1.000 47.548  0 325 TYR A C   1 ? 
ATOM   2362 O O   . TYR A 1 321 ? -5.194 -42.870 12.425  1.000 51.606  0 325 TYR A O   1 ? 
ATOM   2363 C CB  . TYR A 1 321 ? -4.774 -46.030 13.390  1.000 44.926  0 325 TYR A CB  1 ? 
ATOM   2364 C CG  . TYR A 1 321 ? -5.023 -47.474 13.045  1.000 48.274  0 325 TYR A CG  1 ? 
ATOM   2365 C CD1 . TYR A 1 321 ? -6.296 -48.036 13.180  1.000 44.974  0 325 TYR A CD1 1 ? 
ATOM   2366 C CD2 . TYR A 1 321 ? -3.991 -48.281 12.583  1.000 42.029  0 325 TYR A CD2 1 ? 
ATOM   2367 C CE1 . TYR A 1 321 ? -6.520 -49.364 12.870  1.000 38.536  0 325 TYR A CE1 1 ? 
ATOM   2368 C CE2 . TYR A 1 321 ? -4.201 -49.608 12.269  1.000 34.846  0 325 TYR A CE2 1 ? 
ATOM   2369 C CZ  . TYR A 1 321 ? -5.457 -50.144 12.416  1.000 41.213  0 325 TYR A CZ  1 ? 
ATOM   2370 O OH  . TYR A 1 321 ? -5.635 -51.465 12.102  1.000 46.448  0 325 TYR A OH  1 ? 
ATOM   2371 N N   . GLN A 1 322 ? -5.740 -43.361 14.554  1.000 46.779  0 326 GLN A N   1 ? 
ATOM   2372 C CA  . GLN A 1 322 ? -5.360 -42.059 15.072  1.000 46.990  0 326 GLN A CA  1 ? 
ATOM   2373 C C   . GLN A 1 322 ? -3.858 -41.975 15.326  1.000 47.156  0 326 GLN A C   1 ? 
ATOM   2374 O O   . GLN A 1 322 ? -3.247 -42.891 15.884  1.000 38.373  0 326 GLN A O   1 ? 
ATOM   2375 C CB  . GLN A 1 322 ? -6.105 -41.769 16.366  1.000 48.045  0 326 GLN A CB  1 ? 
ATOM   2376 C CG  . GLN A 1 322 ? -5.582 -40.551 17.086  1.000 56.323  0 326 GLN A CG  1 ? 
ATOM   2377 C CD  . GLN A 1 322 ? -6.363 -40.260 18.348  1.000 67.684  0 326 GLN A CD  1 ? 
ATOM   2378 O OE1 . GLN A 1 322 ? -7.111 -41.111 18.832  1.000 73.069  0 326 GLN A OE1 1 ? 
ATOM   2379 N NE2 . GLN A 1 322 ? -6.199 -39.054 18.888  1.000 66.082  0 326 GLN A NE2 1 ? 
ATOM   2380 N N   . TRP A 1 323 ? -3.274 -40.854 14.921  1.000 54.001  0 327 TRP A N   1 ? 
ATOM   2381 C CA  . TRP A 1 323 ? -1.876 -40.542 15.159  1.000 49.461  0 327 TRP A CA  1 ? 
ATOM   2382 C C   . TRP A 1 323 ? -1.782 -39.474 16.236  1.000 57.404  0 327 TRP A C   1 ? 
ATOM   2383 O O   . TRP A 1 323 ? -2.518 -38.483 16.197  1.000 63.358  0 327 TRP A O   1 ? 
ATOM   2384 C CB  . TRP A 1 323 ? -1.206 -40.046 13.886  1.000 40.350  0 327 TRP A CB  1 ? 
ATOM   2385 C CG  . TRP A 1 323 ? -1.037 -41.077 12.865  1.000 42.931  0 327 TRP A CG  1 ? 
ATOM   2386 C CD1 . TRP A 1 323 ? -1.986 -41.917 12.381  1.000 46.256  0 327 TRP A CD1 1 ? 
ATOM   2387 C CD2 . TRP A 1 323 ? 0.170  -41.384 12.168  1.000 52.475  0 327 TRP A CD2 1 ? 
ATOM   2388 N NE1 . TRP A 1 323 ? -1.444 -42.737 11.420  1.000 48.390  0 327 TRP A NE1 1 ? 
ATOM   2389 C CE2 . TRP A 1 323 ? -0.120 -42.422 11.269  1.000 49.919  0 327 TRP A CE2 1 ? 
ATOM   2390 C CE3 . TRP A 1 323 ? 1.472  -40.877 12.216  1.000 52.538  0 327 TRP A CE3 1 ? 
ATOM   2391 C CZ2 . TRP A 1 323 ? 0.844  -42.970 10.435  1.000 47.085  0 327 TRP A CZ2 1 ? 
ATOM   2392 C CZ3 . TRP A 1 323 ? 2.423  -41.415 11.373  1.000 48.532  0 327 TRP A CZ3 1 ? 
ATOM   2393 C CH2 . TRP A 1 323 ? 2.108  -42.454 10.502  1.000 39.984  0 327 TRP A CH2 1 ? 
ATOM   2394 N N   . GLU A 1 324 ? -0.883 -39.679 17.191  1.000 52.185  0 328 GLU A N   1 ? 
ATOM   2395 C CA  . GLU A 1 324 ? -0.582 -38.695 18.221  1.000 48.461  0 328 GLU A CA  1 ? 
ATOM   2396 C C   . GLU A 1 324 ? 0.893  -38.348 18.113  1.000 47.477  0 328 GLU A C   1 ? 
ATOM   2397 O O   . GLU A 1 324 ? 1.749  -39.234 18.217  1.000 47.256  0 328 GLU A O   1 ? 
ATOM   2398 C CB  . GLU A 1 324 ? -0.906 -39.228 19.614  1.000 47.650  0 328 GLU A CB  1 ? 
ATOM   2399 C CG  . GLU A 1 324 ? -0.772 -38.191 20.711  1.000 50.572  0 328 GLU A CG  1 ? 
ATOM   2400 C CD  . GLU A 1 324 ? -0.596 -38.826 22.068  1.000 63.342  0 328 GLU A CD  1 ? 
ATOM   2401 O OE1 . GLU A 1 324 ? -1.602 -38.940 22.792  1.000 71.051  0 328 GLU A OE1 1 ? 
ATOM   2402 O OE2 . GLU A 1 324 ? 0.545  -39.214 22.416  1.000 72.435  0 328 GLU A OE2 1 ? 
ATOM   2403 N N   . ASN A 1 325 ? 1.184  -37.068 17.894  1.000 38.584  0 329 ASN A N   1 ? 
ATOM   2404 C CA  . ASN A 1 325 ? 2.554  -36.619 17.716  1.000 31.393  0 329 ASN A CA  1 ? 
ATOM   2405 C C   . ASN A 1 325 ? 3.267  -36.512 19.061  1.000 40.221  0 329 ASN A C   1 ? 
ATOM   2406 O O   . ASN A 1 325 ? 2.702  -35.998 20.034  1.000 44.421  0 329 ASN A O   1 ? 
ATOM   2407 C CB  . ASN A 1 325 ? 2.578  -35.275 16.998  1.000 30.675  0 329 ASN A CB  1 ? 
ATOM   2408 C CG  . ASN A 1 325 ? 3.976  -34.689 16.931  1.000 38.028  0 329 ASN A CG  1 ? 
ATOM   2409 O OD1 . ASN A 1 325 ? 4.300  -33.777 17.678  1.000 38.176  0 329 ASN A OD1 1 ? 
ATOM   2410 N ND2 . ASN A 1 325 ? 4.813  -35.220 16.039  1.000 29.880  0 329 ASN A ND2 1 ? 
ATOM   2411 N N   . ILE A 1 326 ? 4.504  -37.007 19.117  1.000 34.970  0 330 ILE A N   1 ? 
ATOM   2412 C CA  . ILE A 1 326 ? 5.275  -36.973 20.361  1.000 43.329  0 330 ILE A CA  1 ? 
ATOM   2413 C C   . ILE A 1 326 ? 6.179  -35.744 20.413  1.000 50.761  0 330 ILE A C   1 ? 
ATOM   2414 O O   . ILE A 1 326 ? 6.303  -35.087 21.451  1.000 61.321  0 330 ILE A O   1 ? 
ATOM   2415 C CB  . ILE A 1 326 ? 6.087  -38.287 20.530  1.000 35.288  0 330 ILE A CB  1 ? 
ATOM   2416 C CG1 . ILE A 1 326 ? 5.175  -39.461 20.889  1.000 27.798  0 330 ILE A CG1 1 ? 
ATOM   2417 C CG2 . ILE A 1 326 ? 7.130  -38.142 21.633  1.000 30.669  0 330 ILE A CG2 1 ? 
ATOM   2418 C CD1 . ILE A 1 326 ? 5.557  -40.749 20.245  1.000 32.904  0 330 ILE A CD1 1 ? 
ATOM   2419 N N   . LYS A 1 327 ? 6.797  -35.425 19.299  1.000 44.103  0 331 LYS A N   1 ? 
ATOM   2420 C CA  . LYS A 1 327 ? 7.716  -34.320 19.098  1.000 40.973  0 331 LYS A CA  1 ? 
ATOM   2421 C C   . LYS A 1 327 ? 7.964  -34.371 17.595  1.000 39.523  0 331 LYS A C   1 ? 
ATOM   2422 O O   . LYS A 1 327 ? 7.434  -35.275 16.941  1.000 42.839  0 331 LYS A O   1 ? 
ATOM   2423 C CB  . LYS A 1 327 ? 8.979  -34.484 19.962  1.000 39.147  0 331 LYS A CB  1 ? 
ATOM   2424 C CG  . LYS A 1 327 ? 10.076 -35.318 19.335  1.000 38.184  0 331 LYS A CG  1 ? 
ATOM   2425 C CD  . LYS A 1 327 ? 11.054 -35.789 20.367  1.000 39.992  0 331 LYS A CD  1 ? 
ATOM   2426 C CE  . LYS A 1 327 ? 12.465 -35.842 19.831  1.000 38.386  0 331 LYS A CE  1 ? 
ATOM   2427 N NZ  . LYS A 1 327 ? 13.332 -36.357 20.907  1.000 39.544  0 331 LYS A NZ  1 ? 
ATOM   2428 N N   . PRO A 1 328 ? 8.708  -33.449 16.991  1.000 40.186  0 332 PRO A N   1 ? 
ATOM   2429 C CA  . PRO A 1 328 ? 8.835  -33.487 15.523  1.000 45.819  0 332 PRO A CA  1 ? 
ATOM   2430 C C   . PRO A 1 328 ? 9.476  -34.789 15.052  1.000 49.816  0 332 PRO A C   1 ? 
ATOM   2431 O O   . PRO A 1 328 ? 10.465 -35.257 15.624  1.000 46.640  0 332 PRO A O   1 ? 
ATOM   2432 C CB  . PRO A 1 328 ? 9.714  -32.270 15.203  1.000 44.413  0 332 PRO A CB  1 ? 
ATOM   2433 C CG  . PRO A 1 328 ? 9.609  -31.373 16.403  1.000 44.305  0 332 PRO A CG  1 ? 
ATOM   2434 C CD  . PRO A 1 328 ? 9.366  -32.265 17.580  1.000 38.836  0 332 PRO A CD  1 ? 
ATOM   2435 N N   . GLN A 1 329 ? 8.884  -35.376 14.007  1.000 49.482  0 333 GLN A N   1 ? 
ATOM   2436 C CA  . GLN A 1 329 ? 9.325  -36.624 13.380  1.000 45.550  0 333 GLN A CA  1 ? 
ATOM   2437 C C   . GLN A 1 329 ? 9.232  -37.824 14.311  1.000 43.229  0 333 GLN A C   1 ? 
ATOM   2438 O O   . GLN A 1 329 ? 9.826  -38.874 14.031  1.000 44.537  0 333 GLN A O   1 ? 
ATOM   2439 C CB  . GLN A 1 329 ? 10.753 -36.521 12.835  1.000 50.788  0 333 GLN A CB  1 ? 
ATOM   2440 C CG  . GLN A 1 329 ? 10.844 -35.868 11.486  1.000 45.374  0 333 GLN A CG  1 ? 
ATOM   2441 C CD  . GLN A 1 329 ? 10.725 -34.380 11.614  1.000 50.293  0 333 GLN A CD  1 ? 
ATOM   2442 O OE1 . GLN A 1 329 ? 11.665 -33.717 12.051  1.000 48.272  0 333 GLN A OE1 1 ? 
ATOM   2443 N NE2 . GLN A 1 329 ? 9.552  -33.840 11.274  1.000 53.375  0 333 GLN A NE2 1 ? 
ATOM   2444 N N   . VAL A 1 330 ? 8.511  -37.707 15.424  1.000 32.159  0 334 VAL A N   1 ? 
ATOM   2445 C CA  . VAL A 1 330 ? 8.286  -38.829 16.323  1.000 31.477  0 334 VAL A CA  1 ? 
ATOM   2446 C C   . VAL A 1 330 ? 6.791  -38.894 16.607  1.000 36.404  0 334 VAL A C   1 ? 
ATOM   2447 O O   . VAL A 1 330 ? 6.240  -37.998 17.254  1.000 44.066  0 334 VAL A O   1 ? 
ATOM   2448 C CB  . VAL A 1 330 ? 9.090  -38.704 17.621  1.000 30.127  0 334 VAL A CB  1 ? 
ATOM   2449 C CG1 . VAL A 1 330 ? 9.092  -40.020 18.351  1.000 25.371  0 334 VAL A CG1 1 ? 
ATOM   2450 C CG2 . VAL A 1 330 ? 10.506 -38.265 17.315  1.000 33.170  0 334 VAL A CG2 1 ? 
ATOM   2451 N N   . ASP A 1 331 ? 6.136  -39.951 16.132  1.000 39.528  0 335 ASP A N   1 ? 
ATOM   2452 C CA  . ASP A 1 331 ? 4.690  -40.081 16.237  1.000 41.771  0 335 ASP A CA  1 ? 
ATOM   2453 C C   . ASP A 1 331 ? 4.310  -41.441 16.800  1.000 40.634  0 335 ASP A C   1 ? 
ATOM   2454 O O   . ASP A 1 331 ? 5.038  -42.427 16.660  1.000 40.589  0 335 ASP A O   1 ? 
ATOM   2455 C CB  . ASP A 1 331 ? 3.999  -39.899 14.876  1.000 43.882  0 335 ASP A CB  1 ? 
ATOM   2456 C CG  . ASP A 1 331 ? 4.253  -38.537 14.269  1.000 49.611  0 335 ASP A CG  1 ? 
ATOM   2457 O OD1 . ASP A 1 331 ? 3.652  -37.558 14.742  1.000 50.856  0 335 ASP A OD1 1 ? 
ATOM   2458 O OD2 . ASP A 1 331 ? 5.055  -38.442 13.314  1.000 53.785  0 335 ASP A OD2 1 ? 
ATOM   2459 N N   . HIS A 1 332 ? 3.153  -41.467 17.442  1.000 44.663  0 336 HIS A N   1 ? 
ATOM   2460 C CA  . HIS A 1 332 ? 2.488  -42.689 17.858  1.000 44.279  0 336 HIS A CA  1 ? 
ATOM   2461 C C   . HIS A 1 332 ? 1.389  -43.020 16.863  1.000 46.285  0 336 HIS A C   1 ? 
ATOM   2462 O O   . HIS A 1 332 ? 0.678  -42.133 16.385  1.000 41.350  0 336 HIS A O   1 ? 
ATOM   2463 C CB  . HIS A 1 332 ? 1.855  -42.529 19.240  1.000 42.116  0 336 HIS A CB  1 ? 
ATOM   2464 C CG  . HIS A 1 332 ? 2.704  -43.019 20.363  1.000 30.898  0 336 HIS A CG  1 ? 
ATOM   2465 N ND1 . HIS A 1 332 ? 2.697  -42.428 21.602  1.000 29.288  0 336 HIS A ND1 1 ? 
ATOM   2466 C CD2 . HIS A 1 332 ? 3.577  -44.050 20.440  1.000 32.680  0 336 HIS A CD2 1 ? 
ATOM   2467 C CE1 . HIS A 1 332 ? 3.539  -43.065 22.398  1.000 31.375  0 336 HIS A CE1 1 ? 
ATOM   2468 N NE2 . HIS A 1 332 ? 4.079  -44.059 21.720  1.000 31.504  0 336 HIS A NE2 1 ? 
ATOM   2469 N N   . VAL A 1 333 ? 1.235  -44.296 16.563  1.000 47.298  0 337 VAL A N   1 ? 
ATOM   2470 C CA  . VAL A 1 333 ? 0.039  -44.778 15.897  1.000 44.661  0 337 VAL A CA  1 ? 
ATOM   2471 C C   . VAL A 1 333 ? -0.687 -45.643 16.906  1.000 44.316  0 337 VAL A C   1 ? 
ATOM   2472 O O   . VAL A 1 333 ? -0.077 -46.523 17.530  1.000 37.833  0 337 VAL A O   1 ? 
ATOM   2473 C CB  . VAL A 1 333 ? 0.358  -45.549 14.607  1.000 48.693  0 337 VAL A CB  1 ? 
ATOM   2474 C CG1 . VAL A 1 333 ? -0.920 -46.129 14.013  1.000 47.416  0 337 VAL A CG1 1 ? 
ATOM   2475 C CG2 . VAL A 1 333 ? 1.026  -44.625 13.611  1.000 48.840  0 337 VAL A CG2 1 ? 
ATOM   2476 N N   . ILE A 1 334 ? -1.974 -45.366 17.095  1.000 45.798  0 338 ILE A N   1 ? 
ATOM   2477 C CA  . ILE A 1 334 ? -2.791 -46.038 18.097  1.000 47.493  0 338 ILE A CA  1 ? 
ATOM   2478 C C   . ILE A 1 334 ? -3.733 -47.001 17.389  1.000 44.018  0 338 ILE A C   1 ? 
ATOM   2479 O O   . ILE A 1 334 ? -4.530 -46.598 16.534  1.000 48.277  0 338 ILE A O   1 ? 
ATOM   2480 C CB  . ILE A 1 334 ? -3.562 -45.029 18.957  1.000 47.698  0 338 ILE A CB  1 ? 
ATOM   2481 C CG1 . ILE A 1 334 ? -2.603 -43.928 19.430  1.000 47.385  0 338 ILE A CG1 1 ? 
ATOM   2482 C CG2 . ILE A 1 334 ? -4.192 -45.732 20.144  1.000 43.010  0 338 ILE A CG2 1 ? 
ATOM   2483 C CD1 . ILE A 1 334 ? -3.289 -42.683 19.920  1.000 42.992  0 338 ILE A CD1 1 ? 
ATOM   2484 N N   . PHE A 1 335 ? -3.631 -48.247 17.728  1.000 44.042  0 339 PHE A N   1 ? 
ATOM   2485 C CA  . PHE A 1 335 ? -4.490 -49.284 17.193  1.000 43.197  0 339 PHE A CA  1 ? 
ATOM   2486 C C   . PHE A 1 335 ? -5.775 -49.382 18.009  1.000 46.740  0 339 PHE A C   1 ? 
ATOM   2487 O O   . PHE A 1 335 ? -5.856 -48.863 19.128  1.000 49.037  0 339 PHE A O   1 ? 
ATOM   2488 C CB  . PHE A 1 335 ? -3.737 -50.612 17.182  1.000 42.442  0 339 PHE A CB  1 ? 
ATOM   2489 C CG  . PHE A 1 335 ? -2.704 -50.698 16.100  1.000 37.939  0 339 PHE A CG  1 ? 
ATOM   2490 C CD1 . PHE A 1 335 ? -1.526 -49.962 16.185  1.000 41.584  0 339 PHE A CD1 1 ? 
ATOM   2491 C CD2 . PHE A 1 335 ? -2.918 -51.493 14.985  1.000 40.242  0 339 PHE A CD2 1 ? 
ATOM   2492 C CE1 . PHE A 1 335 ? -0.575 -50.027 15.183  1.000 39.284  0 339 PHE A CE1 1 ? 
ATOM   2493 C CE2 . PHE A 1 335 ? -1.970 -51.575 13.968  1.000 38.155  0 339 PHE A CE2 1 ? 
ATOM   2494 C CZ  . PHE A 1 335 ? -0.795 -50.838 14.068  1.000 44.637  0 339 PHE A CZ  1 ? 
ATOM   2495 N N   . PRO A 1 336 ? -6.817 -50.012 17.462  1.000 54.543  0 340 PRO A N   1 ? 
ATOM   2496 C CA  . PRO A 1 336 ? -8.125 -49.983 18.142  1.000 54.296  0 340 PRO A CA  1 ? 
ATOM   2497 C C   . PRO A 1 336 ? -8.109 -50.567 19.539  1.000 55.591  0 340 PRO A C   1 ? 
ATOM   2498 O O   . PRO A 1 336 ? -8.889 -50.123 20.389  1.000 61.363  0 340 PRO A O   1 ? 
ATOM   2499 C CB  . PRO A 1 336 ? -9.015 -50.800 17.203  1.000 62.721  0 340 PRO A CB  1 ? 
ATOM   2500 C CG  . PRO A 1 336 ? -8.354 -50.674 15.865  1.000 63.763  0 340 PRO A CG  1 ? 
ATOM   2501 C CD  . PRO A 1 336 ? -6.898 -50.672 16.146  1.000 60.336  0 340 PRO A CD  1 ? 
ATOM   2502 N N   . ASP A 1 337 ? -7.255 -51.555 19.801  1.000 55.878  0 341 ASP A N   1 ? 
ATOM   2503 C CA  . ASP A 1 337 ? -7.092 -52.117 21.135  1.000 43.510  0 341 ASP A CA  1 ? 
ATOM   2504 C C   . ASP A 1 337 ? -6.223 -51.250 22.038  1.000 48.640  0 341 ASP A C   1 ? 
ATOM   2505 O O   . ASP A 1 337 ? -5.760 -51.745 23.070  1.000 53.967  0 341 ASP A O   1 ? 
ATOM   2506 C CB  . ASP A 1 337 ? -6.489 -53.531 21.054  1.000 33.967  0 341 ASP A CB  1 ? 
ATOM   2507 C CG  . ASP A 1 337 ? -5.075 -53.542 20.507  1.000 44.197  0 341 ASP A CG  1 ? 
ATOM   2508 O OD1 . ASP A 1 337 ? -4.592 -52.487 20.060  1.000 50.717  0 341 ASP A OD1 1 ? 
ATOM   2509 O OD2 . ASP A 1 337 ? -4.432 -54.611 20.512  1.000 52.627  0 341 ASP A OD2 1 ? 
ATOM   2510 N N   . GLY A 1 338 ? -5.956 -49.998 21.652  1.000 44.726  0 342 GLY A N   1 ? 
ATOM   2511 C CA  . GLY A 1 338 ? -5.143 -49.073 22.421  1.000 36.720  0 342 GLY A CA  1 ? 
ATOM   2512 C C   . GLY A 1 338 ? -3.648 -49.321 22.400  1.000 44.382  0 342 GLY A C   1 ? 
ATOM   2513 O O   . GLY A 1 338 ? -2.901 -48.565 23.040  1.000 50.409  0 342 GLY A O   1 ? 
ATOM   2514 N N   . LYS A 1 339 ? -3.184 -50.348 21.700  1.000 38.039  0 343 LYS A N   1 ? 
ATOM   2515 C CA  . LYS A 1 339 ? -1.755 -50.591 21.576  1.000 34.541  0 343 LYS A CA  1 ? 
ATOM   2516 C C   . LYS A 1 339 ? -1.119 -49.588 20.616  1.000 36.707  0 343 LYS A C   1 ? 
ATOM   2517 O O   . LYS A 1 339 ? -1.662 -49.301 19.542  1.000 43.234  0 343 LYS A O   1 ? 
ATOM   2518 C CB  . LYS A 1 339 ? -1.542 -52.017 21.093  1.000 38.852  0 343 LYS A CB  1 ? 
ATOM   2519 C CG  . LYS A 1 339 ? -0.149 -52.371 20.786  1.000 46.650  0 343 LYS A CG  1 ? 
ATOM   2520 C CD  . LYS A 1 339 ? -0.133 -53.262 19.575  1.000 57.896  0 343 LYS A CD  1 ? 
ATOM   2521 C CE  . LYS A 1 339 ? 0.413  -52.532 18.371  1.000 53.343  0 343 LYS A CE  1 ? 
ATOM   2522 N NZ  . LYS A 1 339 ? 0.438  -53.475 17.232  1.000 50.317  0 343 LYS A NZ  1 ? 
ATOM   2523 N N   . ARG A 1 340 ? 0.045  -49.059 21.007  1.000 30.920  0 344 ARG A N   1 ? 
ATOM   2524 C CA  . ARG A 1 340 ? 0.718  -47.979 20.291  1.000 34.473  0 344 ARG A CA  1 ? 
ATOM   2525 C C   . ARG A 1 340 ? 2.041  -48.430 19.675  1.000 35.044  0 344 ARG A C   1 ? 
ATOM   2526 O O   . ARG A 1 340 ? 2.811  -49.169 20.293  1.000 32.485  0 344 ARG A O   1 ? 
ATOM   2527 C CB  . ARG A 1 340 ? 0.978  -46.786 21.216  1.000 35.209  0 344 ARG A CB  1 ? 
ATOM   2528 C CG  . ARG A 1 340 ? -0.309 -46.130 21.669  1.000 51.327  0 344 ARG A CG  1 ? 
ATOM   2529 C CD  . ARG A 1 340 ? -0.170 -45.422 22.994  1.000 54.307  0 344 ARG A CD  1 ? 
ATOM   2530 N NE  . ARG A 1 340 ? 0.078  -44.005 22.768  1.000 57.694  0 344 ARG A NE  1 ? 
ATOM   2531 C CZ  . ARG A 1 340 ? -0.814 -43.040 22.962  1.000 53.109  0 344 ARG A CZ  1 ? 
ATOM   2532 N NH1 . ARG A 1 340 ? -0.474 -41.783 22.719  1.000 58.270  0 344 ARG A NH1 1 ? 
ATOM   2533 N NH2 . ARG A 1 340 ? -2.037 -43.319 23.404  1.000 44.424  0 344 ARG A NH2 1 ? 
ATOM   2534 N N   . ILE A 1 341 ? 2.278  -47.970 18.444  1.000 37.131  0 345 ILE A N   1 ? 
ATOM   2535 C CA  . ILE A 1 341 ? 3.541  -48.099 17.727  1.000 31.343  0 345 ILE A CA  1 ? 
ATOM   2536 C C   . ILE A 1 341 ? 4.194  -46.724 17.634  1.000 34.007  0 345 ILE A C   1 ? 
ATOM   2537 O O   . ILE A 1 341 ? 3.524  -45.722 17.350  1.000 37.491  0 345 ILE A O   1 ? 
ATOM   2538 C CB  . ILE A 1 341 ? 3.317  -48.679 16.318  1.000 39.626  0 345 ILE A CB  1 ? 
ATOM   2539 C CG1 . ILE A 1 341 ? 2.830  -50.118 16.412  1.000 50.269  0 345 ILE A CG1 1 ? 
ATOM   2540 C CG2 . ILE A 1 341 ? 4.586  -48.617 15.496  1.000 40.981  0 345 ILE A CG2 1 ? 
ATOM   2541 C CD1 . ILE A 1 341 ? 3.483  -50.910 17.502  1.000 53.227  0 345 ILE A CD1 1 ? 
ATOM   2542 N N   . ILE A 1 342 ? 5.501  -46.675 17.868  1.000 31.130  0 346 ILE A N   1 ? 
ATOM   2543 C CA  . ILE A 1 342 ? 6.294  -45.468 17.644  1.000 31.401  0 346 ILE A CA  1 ? 
ATOM   2544 C C   . ILE A 1 342 ? 6.883  -45.533 16.245  1.000 35.396  0 346 ILE A C   1 ? 
ATOM   2545 O O   . ILE A 1 342 ? 7.648  -46.455 15.936  1.000 44.063  0 346 ILE A O   1 ? 
ATOM   2546 C CB  . ILE A 1 342 ? 7.417  -45.337 18.678  1.000 32.912  0 346 ILE A CB  1 ? 
ATOM   2547 C CG1 . ILE A 1 342 ? 6.845  -45.221 20.087  1.000 27.585  0 346 ILE A CG1 1 ? 
ATOM   2548 C CG2 . ILE A 1 342 ? 8.319  -44.159 18.303  1.000 24.092  0 346 ILE A CG2 1 ? 
ATOM   2549 C CD1 . ILE A 1 342 ? 7.887  -45.431 21.181  1.000 23.940  0 346 ILE A CD1 1 ? 
ATOM   2550 N N   . ILE A 1 343 ? 6.565  -44.543 15.418  1.000 33.675  0 347 ILE A N   1 ? 
ATOM   2551 C CA  . ILE A 1 343 ? 7.059  -44.448 14.053  1.000 26.803  0 347 ILE A CA  1 ? 
ATOM   2552 C C   . ILE A 1 343 ? 7.918  -43.204 13.967  1.000 29.664  0 347 ILE A C   1 ? 
ATOM   2553 O O   . ILE A 1 343 ? 7.511  -42.134 14.430  1.000 37.902  0 347 ILE A O   1 ? 
ATOM   2554 C CB  . ILE A 1 343 ? 5.908  -44.435 13.032  1.000 35.523  0 347 ILE A CB  1 ? 
ATOM   2555 C CG1 . ILE A 1 343 ? 4.904  -45.515 13.393  1.000 41.484  0 347 ILE A CG1 1 ? 
ATOM   2556 C CG2 . ILE A 1 343 ? 6.401  -44.553 11.574  1.000 33.715  0 347 ILE A CG2 1 ? 
ATOM   2557 C CD1 . ILE A 1 343 ? 4.073  -45.912 12.234  1.000 54.980  0 347 ILE A CD1 1 ? 
ATOM   2558 N N   . LEU A 1 344 ? 9.142  -43.363 13.456  1.000 28.374  0 348 LEU A N   1 ? 
ATOM   2559 C CA  . LEU A 1 344 ? 10.078 -42.249 13.315  1.000 35.057  0 348 LEU A CA  1 ? 
ATOM   2560 C C   . LEU A 1 344 ? 9.938  -41.646 11.926  1.000 32.825  0 348 LEU A C   1 ? 
ATOM   2561 O O   . LEU A 1 344 ? 9.900  -42.379 10.929  1.000 32.304  0 348 LEU A O   1 ? 
ATOM   2562 C CB  . LEU A 1 344 ? 11.523 -42.693 13.534  1.000 36.939  0 348 LEU A CB  1 ? 
ATOM   2563 C CG  . LEU A 1 344 ? 11.735 -43.432 14.856  1.000 40.500  0 348 LEU A CG  1 ? 
ATOM   2564 C CD1 . LEU A 1 344 ? 13.198 -43.771 15.081  1.000 35.717  0 348 LEU A CD1 1 ? 
ATOM   2565 C CD2 . LEU A 1 344 ? 11.189 -42.618 16.019  1.000 37.183  0 348 LEU A CD2 1 ? 
ATOM   2566 N N   . ALA A 1 345 ? 9.850  -40.312 11.869  1.000 29.627  0 349 ALA A N   1 ? 
ATOM   2567 C CA  . ALA A 1 345 ? 9.892  -39.552 10.608  1.000 30.801  0 349 ALA A CA  1 ? 
ATOM   2568 C C   . ALA A 1 345 ? 8.855  -40.047 9.609   1.000 39.792  0 349 ALA A C   1 ? 
ATOM   2569 O O   . ALA A 1 345 ? 9.087  -40.013 8.400   1.000 44.334  0 349 ALA A O   1 ? 
ATOM   2570 C CB  . ALA A 1 345 ? 11.285 -39.597 9.973   1.000 35.920  0 349 ALA A CB  1 ? 
ATOM   2571 N N   . GLU A 1 346 ? 7.712  -40.535 10.107  1.000 41.421  0 350 GLU A N   1 ? 
ATOM   2572 C CA  . GLU A 1 346 ? 6.627  -41.031 9.247   1.000 47.761  0 350 GLU A CA  1 ? 
ATOM   2573 C C   . GLU A 1 346 ? 7.136  -42.068 8.249   1.000 46.032  0 350 GLU A C   1 ? 
ATOM   2574 O O   . GLU A 1 346 ? 6.574  -42.232 7.167   1.000 52.867  0 350 GLU A O   1 ? 
ATOM   2575 C CB  . GLU A 1 346 ? 5.916  -39.886 8.510   1.000 40.986  0 350 GLU A CB  1 ? 
ATOM   2576 C CG  . GLU A 1 346 ? 5.246  -38.863 9.412   1.000 43.621  0 350 GLU A CG  1 ? 
ATOM   2577 C CD  . GLU A 1 346 ? 4.978  -37.522 8.714   1.000 52.335  0 350 GLU A CD  1 ? 
ATOM   2578 O OE1 . GLU A 1 346 ? 4.721  -37.501 7.492   1.000 54.338  0 350 GLU A OE1 1 ? 
ATOM   2579 O OE2 . GLU A 1 346 ? 5.034  -36.480 9.398   1.000 59.352  0 350 GLU A OE2 1 ? 
ATOM   2580 N N   . GLY A 1 347 ? 8.216  -42.761 8.605   1.000 42.508  0 351 GLY A N   1 ? 
ATOM   2581 C CA  . GLY A 1 347 ? 8.769  -43.814 7.780   1.000 37.328  0 351 GLY A CA  1 ? 
ATOM   2582 C C   . GLY A 1 347 ? 9.771  -43.385 6.730   1.000 42.797  0 351 GLY A C   1 ? 
ATOM   2583 O O   . GLY A 1 347 ? 10.106 -44.198 5.861   1.000 48.993  0 351 GLY A O   1 ? 
ATOM   2584 N N   . ARG A 1 348 ? 10.242 -42.138 6.761   1.000 43.021  0 352 ARG A N   1 ? 
ATOM   2585 C CA  . ARG A 1 348 ? 11.336 -41.696 5.904   1.000 43.566  0 352 ARG A CA  1 ? 
ATOM   2586 C C   . ARG A 1 348 ? 12.667 -41.858 6.634   1.000 48.269  0 352 ARG A C   1 ? 
ATOM   2587 O O   . ARG A 1 348 ? 12.705 -42.154 7.833   1.000 55.899  0 352 ARG A O   1 ? 
ATOM   2588 C CB  . ARG A 1 348 ? 11.138 -40.246 5.458   1.000 49.967  0 352 ARG A CB  1 ? 
ATOM   2589 C CG  . ARG A 1 348 ? 9.943  -40.067 4.524   1.000 57.975  0 352 ARG A CG  1 ? 
ATOM   2590 C CD  . ARG A 1 348 ? 8.758  -39.459 5.248   1.000 62.918  0 352 ARG A CD  1 ? 
ATOM   2591 N NE  . ARG A 1 348 ? 7.482  -39.656 4.556   1.000 71.338  0 352 ARG A NE  1 ? 
ATOM   2592 C CZ  . ARG A 1 348 ? 7.141  -39.073 3.408   1.000 76.333  0 352 ARG A CZ  1 ? 
ATOM   2593 N NH1 . ARG A 1 348 ? 7.985  -38.262 2.776   1.000 81.315  0 352 ARG A NH1 1 ? 
ATOM   2594 N NH2 . ARG A 1 348 ? 5.948  -39.315 2.880   1.000 68.142  0 352 ARG A NH2 1 ? 
ATOM   2595 N N   . LEU A 1 349 ? 13.766 -41.668 5.886   1.000 47.003  0 353 LEU A N   1 ? 
ATOM   2596 C CA  . LEU A 1 349 ? 15.133 -41.921 6.348   1.000 42.076  0 353 LEU A CA  1 ? 
ATOM   2597 C C   . LEU A 1 349 ? 15.326 -41.496 7.802   1.000 46.471  0 353 LEU A C   1 ? 
ATOM   2598 O O   . LEU A 1 349 ? 15.332 -40.300 8.116   1.000 47.427  0 353 LEU A O   1 ? 
ATOM   2599 C CB  . LEU A 1 349 ? 16.147 -41.214 5.436   1.000 38.699  0 353 LEU A CB  1 ? 
ATOM   2600 C CG  . LEU A 1 349 ? 16.383 -41.859 4.054   1.000 45.061  0 353 LEU A CG  1 ? 
ATOM   2601 C CD1 . LEU A 1 349 ? 16.928 -40.874 3.022   1.000 35.454  0 353 LEU A CD1 1 ? 
ATOM   2602 C CD2 . LEU A 1 349 ? 17.318 -43.060 4.146   1.000 42.705  0 353 LEU A CD2 1 ? 
ATOM   2603 N N   . VAL A 1 350 ? 15.455 -42.481 8.699   1.000 46.198  0 354 VAL A N   1 ? 
ATOM   2604 C CA  . VAL A 1 350 ? 15.477 -42.193 10.133  1.000 42.789  0 354 VAL A CA  1 ? 
ATOM   2605 C C   . VAL A 1 350 ? 16.781 -41.512 10.520  1.000 44.719  0 354 VAL A C   1 ? 
ATOM   2606 O O   . VAL A 1 350 ? 16.793 -40.600 11.355  1.000 46.948  0 354 VAL A O   1 ? 
ATOM   2607 C CB  . VAL A 1 350 ? 15.232 -43.477 10.957  1.000 44.371  0 354 VAL A CB  1 ? 
ATOM   2608 C CG1 . VAL A 1 350 ? 16.208 -44.633 10.537  1.000 48.553  0 354 VAL A CG1 1 ? 
ATOM   2609 C CG2 . VAL A 1 350 ? 15.384 -43.186 12.433  1.000 39.328  0 354 VAL A CG2 1 ? 
ATOM   2610 N N   . ASN A 1 351 ? 17.892 -41.916 9.903   1.000 42.176  0 355 ASN A N   1 ? 
ATOM   2611 C CA  . ASN A 1 351 ? 19.178 -41.366 10.311  1.000 41.763  0 355 ASN A CA  1 ? 
ATOM   2612 C C   . ASN A 1 351 ? 19.293 -39.886 9.936   1.000 45.176  0 355 ASN A C   1 ? 
ATOM   2613 O O   . ASN A 1 351 ? 19.742 -39.067 10.751  1.000 36.873  0 355 ASN A O   1 ? 
ATOM   2614 C CB  . ASN A 1 351 ? 20.336 -42.208 9.740   1.000 33.454  0 355 ASN A CB  1 ? 
ATOM   2615 C CG  . ASN A 1 351 ? 20.385 -42.237 8.208   1.000 48.869  0 355 ASN A CG  1 ? 
ATOM   2616 O OD1 . ASN A 1 351 ? 19.342 -42.279 7.534   1.000 44.979  0 355 ASN A OD1 1 ? 
ATOM   2617 N ND2 . ASN A 1 351 ? 21.609 -42.234 7.651   1.000 49.177  0 355 ASN A ND2 1 ? 
ATOM   2618 N N   . LEU A 1 352 ? 18.839 -39.512 8.734   1.000 43.500  0 356 LEU A N   1 ? 
ATOM   2619 C CA  . LEU A 1 352 ? 18.810 -38.112 8.326   1.000 44.926  0 356 LEU A CA  1 ? 
ATOM   2620 C C   . LEU A 1 352 ? 17.565 -37.387 8.818   1.000 52.269  0 356 LEU A C   1 ? 
ATOM   2621 O O   . LEU A 1 352 ? 17.611 -36.164 9.018   1.000 45.176  0 356 LEU A O   1 ? 
ATOM   2622 C CB  . LEU A 1 352 ? 18.903 -37.998 6.795   1.000 45.242  0 356 LEU A CB  1 ? 
ATOM   2623 C CG  . LEU A 1 352 ? 20.289 -38.292 6.200   1.000 49.535  0 356 LEU A CG  1 ? 
ATOM   2624 C CD1 . LEU A 1 352 ? 20.253 -39.426 5.184   1.000 49.580  0 356 LEU A CD1 1 ? 
ATOM   2625 C CD2 . LEU A 1 352 ? 20.942 -37.038 5.616   1.000 43.108  0 356 LEU A CD2 1 ? 
ATOM   2626 N N   . GLY A 1 353 ? 16.461 -38.113 9.033   1.000 52.285  0 357 GLY A N   1 ? 
ATOM   2627 C CA  . GLY A 1 353 ? 15.210 -37.498 9.441   1.000 54.507  0 357 GLY A CA  1 ? 
ATOM   2628 C C   . GLY A 1 353 ? 15.142 -37.164 10.915  1.000 54.191  0 357 GLY A C   1 ? 
ATOM   2629 O O   . GLY A 1 353 ? 14.621 -36.112 11.302  1.000 56.573  0 357 GLY A O   1 ? 
ATOM   2630 N N   . CYS A 1 354 ? 15.677 -38.057 11.748  1.000 49.701  0 358 CYS A N   1 ? 
ATOM   2631 C CA  . CYS A 1 354 ? 15.693 -37.870 13.190  1.000 37.741  0 358 CYS A CA  1 ? 
ATOM   2632 C C   . CYS A 1 354 ? 17.078 -37.538 13.729  1.000 38.218  0 358 CYS A C   1 ? 
ATOM   2633 O O   . CYS A 1 354 ? 17.219 -37.319 14.935  1.000 47.943  0 358 CYS A O   1 ? 
ATOM   2634 C CB  . CYS A 1 354 ? 15.136 -39.120 13.891  1.000 32.185  0 358 CYS A CB  1 ? 
ATOM   2635 S SG  . CYS A 1 354 ? 13.370 -39.478 13.516  1.000 44.824  0 358 CYS A SG  1 ? 
ATOM   2636 N N   . ALA A 1 355 ? 18.102 -37.502 12.876  1.000 39.636  0 359 ALA A N   1 ? 
ATOM   2637 C CA  . ALA A 1 355 ? 19.426 -37.030 13.279  1.000 43.929  0 359 ALA A CA  1 ? 
ATOM   2638 C C   . ALA A 1 355 ? 20.056 -36.185 12.174  1.000 44.447  0 359 ALA A C   1 ? 
ATOM   2639 O O   . ALA A 1 355 ? 19.371 -35.383 11.532  1.000 51.314  0 359 ALA A O   1 ? 
ATOM   2640 C CB  . ALA A 1 355 ? 20.338 -38.204 13.650  1.000 43.545  0 359 ALA A CB  1 ? 
ATOM   2641 N N   . THR A 1 356 ? 21.355 -36.353 11.929  1.000 43.516  0 360 THR A N   1 ? 
ATOM   2642 C CA  . THR A 1 356 ? 22.064 -35.511 10.970  1.000 46.327  0 360 THR A CA  1 ? 
ATOM   2643 C C   . THR A 1 356 ? 22.740 -36.319 9.866   1.000 48.193  0 360 THR A C   1 ? 
ATOM   2644 O O   . THR A 1 356 ? 23.702 -35.835 9.243   1.000 52.114  0 360 THR A O   1 ? 
ATOM   2645 C CB  . THR A 1 356 ? 23.096 -34.640 11.688  1.000 37.928  0 360 THR A CB  1 ? 
ATOM   2646 O OG1 . THR A 1 356 ? 23.855 -35.453 12.584  1.000 39.810  0 360 THR A OG1 1 ? 
ATOM   2647 C CG2 . THR A 1 356 ? 22.399 -33.557 12.491  1.000 41.121  0 360 THR A CG2 1 ? 
ATOM   2648 N N   . GLY A 1 357 ? 22.248 -37.530 9.599   1.000 38.507  0 361 GLY A N   1 ? 
ATOM   2649 C CA  . GLY A 1 357 ? 22.888 -38.342 8.594   1.000 47.508  0 361 GLY A CA  1 ? 
ATOM   2650 C C   . GLY A 1 357 ? 24.283 -38.797 9.010   1.000 51.248  0 361 GLY A C   1 ? 
ATOM   2651 O O   . GLY A 1 357 ? 24.667 -38.796 10.192  1.000 45.871  0 361 GLY A O   1 ? 
ATOM   2652 N N   . HIS A 1 358 ? 25.044 -39.213 8.003   1.000 46.600  0 362 HIS A N   1 ? 
ATOM   2653 C CA  . HIS A 1 358 ? 26.370 -39.729 8.261   1.000 43.250  0 362 HIS A CA  1 ? 
ATOM   2654 C C   . HIS A 1 358 ? 27.299 -38.582 8.649   1.000 45.587  0 362 HIS A C   1 ? 
ATOM   2655 O O   . HIS A 1 358 ? 27.078 -37.432 8.257   1.000 50.353  0 362 HIS A O   1 ? 
ATOM   2656 C CB  . HIS A 1 358 ? 26.905 -40.451 7.034   1.000 52.346  0 362 HIS A CB  1 ? 
ATOM   2657 C CG  . HIS A 1 358 ? 26.108 -41.658 6.644   1.000 51.559  0 362 HIS A CG  1 ? 
ATOM   2658 N ND1 . HIS A 1 358 ? 26.076 -42.149 5.356   1.000 49.980  0 362 HIS A ND1 1 ? 
ATOM   2659 C CD2 . HIS A 1 358 ? 25.319 -42.475 7.374   1.000 49.680  0 362 HIS A CD2 1 ? 
ATOM   2660 C CE1 . HIS A 1 358 ? 25.304 -43.217 5.311   1.000 44.347  0 362 HIS A CE1 1 ? 
ATOM   2661 N NE2 . HIS A 1 358 ? 24.833 -43.438 6.522   1.000 52.854  0 362 HIS A NE2 1 ? 
ATOM   2662 N N   . PRO A 1 359 ? 28.322 -38.859 9.448   1.000 38.807  0 363 PRO A N   1 ? 
ATOM   2663 C CA  . PRO A 1 359 ? 29.261 -37.805 9.815   1.000 39.257  0 363 PRO A CA  1 ? 
ATOM   2664 C C   . PRO A 1 359 ? 30.039 -37.353 8.598   1.000 46.874  0 363 PRO A C   1 ? 
ATOM   2665 O O   . PRO A 1 359 ? 30.087 -38.027 7.566   1.000 47.253  0 363 PRO A O   1 ? 
ATOM   2666 C CB  . PRO A 1 359 ? 30.173 -38.475 10.841  1.000 39.902  0 363 PRO A CB  1 ? 
ATOM   2667 C CG  . PRO A 1 359 ? 29.386 -39.634 11.333  1.000 46.558  0 363 PRO A CG  1 ? 
ATOM   2668 C CD  . PRO A 1 359 ? 28.606 -40.112 10.159  1.000 36.202  0 363 PRO A CD  1 ? 
ATOM   2669 N N   . SER A 1 360 ? 30.669 -36.190 8.746   1.000 44.737  0 364 SER A N   1 ? 
ATOM   2670 C CA  . SER A 1 360 ? 31.285 -35.537 7.602   1.000 31.554  0 364 SER A CA  1 ? 
ATOM   2671 C C   . SER A 1 360 ? 32.435 -36.360 7.025   1.000 32.857  0 364 SER A C   1 ? 
ATOM   2672 O O   . SER A 1 360 ? 32.640 -36.349 5.803   1.000 28.427  0 364 SER A O   1 ? 
ATOM   2673 C CB  . SER A 1 360 ? 31.746 -34.126 7.996   1.000 29.332  0 364 SER A CB  1 ? 
ATOM   2674 O OG  . SER A 1 360 ? 32.251 -34.083 9.327   1.000 41.710  0 364 SER A OG  1 ? 
ATOM   2675 N N   . PHE A 1 361 ? 33.183 -37.085 7.869   1.000 30.612  0 365 PHE A N   1 ? 
ATOM   2676 C CA  . PHE A 1 361 ? 34.384 -37.772 7.385   1.000 31.135  0 365 PHE A CA  1 ? 
ATOM   2677 C C   . PHE A 1 361 ? 34.036 -38.814 6.328   1.000 39.013  0 365 PHE A C   1 ? 
ATOM   2678 O O   . PHE A 1 361 ? 34.663 -38.867 5.259   1.000 36.491  0 365 PHE A O   1 ? 
ATOM   2679 C CB  . PHE A 1 361 ? 35.161 -38.424 8.537   1.000 26.856  0 365 PHE A CB  1 ? 
ATOM   2680 C CG  . PHE A 1 361 ? 36.379 -39.203 8.080   1.000 33.080  0 365 PHE A CG  1 ? 
ATOM   2681 C CD1 . PHE A 1 361 ? 37.557 -38.544 7.729   1.000 23.929  0 365 PHE A CD1 1 ? 
ATOM   2682 C CD2 . PHE A 1 361 ? 36.351 -40.604 7.988   1.000 23.592  0 365 PHE A CD2 1 ? 
ATOM   2683 C CE1 . PHE A 1 361 ? 38.698 -39.273 7.295   1.000 25.764  0 365 PHE A CE1 1 ? 
ATOM   2684 C CE2 . PHE A 1 361 ? 37.480 -41.337 7.547   1.000 23.487  0 365 PHE A CE2 1 ? 
ATOM   2685 C CZ  . PHE A 1 361 ? 38.659 -40.667 7.210   1.000 23.616  0 365 PHE A CZ  1 ? 
ATOM   2686 N N   . VAL A 1 362 ? 33.032 -39.656 6.600   1.000 38.794  0 366 VAL A N   1 ? 
ATOM   2687 C CA  . VAL A 1 362 ? 32.701 -40.667 5.600   1.000 33.104  0 366 VAL A CA  1 ? 
ATOM   2688 C C   . VAL A 1 362 ? 31.997 -40.026 4.402   1.000 31.672  0 366 VAL A C   1 ? 
ATOM   2689 O O   . VAL A 1 362 ? 32.194 -40.460 3.255   1.000 32.485  0 366 VAL A O   1 ? 
ATOM   2690 C CB  . VAL A 1 362 ? 31.907 -41.829 6.235   1.000 30.980  0 366 VAL A CB  1 ? 
ATOM   2691 C CG1 . VAL A 1 362 ? 30.435 -41.497 6.423   1.000 25.114  0 366 VAL A CG1 1 ? 
ATOM   2692 C CG2 . VAL A 1 362 ? 32.084 -43.081 5.404   1.000 34.304  0 366 VAL A CG2 1 ? 
ATOM   2693 N N   . MET A 1 363 ? 31.234 -38.945 4.622   1.000 27.809  0 367 MET A N   1 ? 
ATOM   2694 C CA  . MET A 1 363 ? 30.681 -38.208 3.484   1.000 35.007  0 367 MET A CA  1 ? 
ATOM   2695 C C   . MET A 1 363 ? 31.782 -37.651 2.587   1.000 37.886  0 367 MET A C   1 ? 
ATOM   2696 O O   . MET A 1 363 ? 31.564 -37.468 1.385   1.000 36.318  0 367 MET A O   1 ? 
ATOM   2697 C CB  . MET A 1 363 ? 29.766 -37.068 3.954   1.000 38.607  0 367 MET A CB  1 ? 
ATOM   2698 C CG  . MET A 1 363 ? 28.581 -37.506 4.813   1.000 41.408  0 367 MET A CG  1 ? 
ATOM   2699 S SD  . MET A 1 363 ? 27.552 -38.739 4.004   1.000 43.105  0 367 MET A SD  1 ? 
ATOM   2700 C CE  . MET A 1 363 ? 27.387 -38.032 2.379   1.000 32.651  0 367 MET A CE  1 ? 
ATOM   2701 N N   . SER A 1 364 ? 32.967 -37.387 3.149   1.000 26.753  0 368 SER A N   1 ? 
ATOM   2702 C CA  . SER A 1 364 ? 34.062 -36.846 2.361   1.000 28.959  0 368 SER A CA  1 ? 
ATOM   2703 C C   . SER A 1 364 ? 34.534 -37.847 1.317   1.000 32.520  0 368 SER A C   1 ? 
ATOM   2704 O O   . SER A 1 364 ? 34.848 -37.472 0.181   1.000 34.415  0 368 SER A O   1 ? 
ATOM   2705 C CB  . SER A 1 364 ? 35.216 -36.448 3.287   1.000 38.852  0 368 SER A CB  1 ? 
ATOM   2706 O OG  . SER A 1 364 ? 36.360 -36.019 2.571   1.000 26.840  0 368 SER A OG  1 ? 
ATOM   2707 N N   . ALA A 1 365 ? 34.601 -39.124 1.686   1.000 33.320  0 369 ALA A N   1 ? 
ATOM   2708 C CA  . ALA A 1 365 ? 34.931 -40.148 0.702   1.000 35.212  0 369 ALA A CA  1 ? 
ATOM   2709 C C   . ALA A 1 365 ? 33.856 -40.233 -0.380  1.000 36.904  0 369 ALA A C   1 ? 
ATOM   2710 O O   . ALA A 1 365 ? 34.171 -40.278 -1.578  1.000 41.315  0 369 ALA A O   1 ? 
ATOM   2711 C CB  . ALA A 1 365 ? 35.133 -41.498 1.392   1.000 27.469  0 369 ALA A CB  1 ? 
ATOM   2712 N N   . SER A 1 366 ? 32.579 -40.243 0.019   1.000 36.668  0 370 SER A N   1 ? 
ATOM   2713 C CA  . SER A 1 366 ? 31.507 -40.251 -0.978  1.000 46.350  0 370 SER A CA  1 ? 
ATOM   2714 C C   . SER A 1 366 ? 31.625 -39.045 -1.892  1.000 43.863  0 370 SER A C   1 ? 
ATOM   2715 O O   . SER A 1 366 ? 31.614 -39.174 -3.122  1.000 40.389  0 370 SER A O   1 ? 
ATOM   2716 C CB  . SER A 1 366 ? 30.128 -40.258 -0.307  1.000 47.364  0 370 SER A CB  1 ? 
ATOM   2717 O OG  . SER A 1 366 ? 29.990 -41.344 0.586   1.000 55.917  0 370 SER A OG  1 ? 
ATOM   2718 N N   . PHE A 1 367 ? 31.784 -37.863 -1.295  1.000 39.481  0 371 PHE A N   1 ? 
ATOM   2719 C CA  . PHE A 1 367 ? 31.714 -36.620 -2.043  1.000 39.699  0 371 PHE A CA  1 ? 
ATOM   2720 C C   . PHE A 1 367 ? 32.957 -36.371 -2.876  1.000 43.800  0 371 PHE A C   1 ? 
ATOM   2721 O O   . PHE A 1 367 ? 32.861 -35.725 -3.922  1.000 36.289  0 371 PHE A O   1 ? 
ATOM   2722 C CB  . PHE A 1 367 ? 31.464 -35.465 -1.082  1.000 42.971  0 371 PHE A CB  1 ? 
ATOM   2723 C CG  . PHE A 1 367 ? 30.052 -35.420 -0.552  1.000 40.584  0 371 PHE A CG  1 ? 
ATOM   2724 C CD1 . PHE A 1 367 ? 29.048 -36.141 -1.169  1.000 40.605  0 371 PHE A CD1 1 ? 
ATOM   2725 C CD2 . PHE A 1 367 ? 29.735 -34.654 0.548   1.000 36.325  0 371 PHE A CD2 1 ? 
ATOM   2726 C CE1 . PHE A 1 367 ? 27.770 -36.102 -0.696  1.000 36.207  0 371 PHE A CE1 1 ? 
ATOM   2727 C CE2 . PHE A 1 367 ? 28.454 -34.608 1.013   1.000 37.818  0 371 PHE A CE2 1 ? 
ATOM   2728 C CZ  . PHE A 1 367 ? 27.469 -35.329 0.389   1.000 36.804  0 371 PHE A CZ  1 ? 
ATOM   2729 N N   . THR A 1 368 ? 34.125 -36.858 -2.431  1.000 49.522  0 372 THR A N   1 ? 
ATOM   2730 C CA  . THR A 1 368 ? 35.300 -36.837 -3.296  1.000 43.566  0 372 THR A CA  1 ? 
ATOM   2731 C C   . THR A 1 368 ? 35.039 -37.657 -4.552  1.000 42.634  0 372 THR A C   1 ? 
ATOM   2732 O O   . THR A 1 368 ? 35.391 -37.245 -5.664  1.000 47.585  0 372 THR A O   1 ? 
ATOM   2733 C CB  . THR A 1 368 ? 36.536 -37.353 -2.539  1.000 45.113  0 372 THR A CB  1 ? 
ATOM   2734 O OG1 . THR A 1 368 ? 36.802 -36.519 -1.399  1.000 35.444  0 372 THR A OG1 1 ? 
ATOM   2735 C CG2 . THR A 1 368 ? 37.787 -37.371 -3.448  1.000 29.635  0 372 THR A CG2 1 ? 
ATOM   2736 N N   . ASN A 1 369 ? 34.379 -38.803 -4.395  1.000 51.672  0 373 ASN A N   1 ? 
ATOM   2737 C CA  . ASN A 1 369 ? 33.941 -39.567 -5.560  1.000 52.633  0 373 ASN A CA  1 ? 
ATOM   2738 C C   . ASN A 1 369 ? 32.973 -38.765 -6.425  1.000 51.683  0 373 ASN A C   1 ? 
ATOM   2739 O O   . ASN A 1 369 ? 33.032 -38.841 -7.659  1.000 45.666  0 373 ASN A O   1 ? 
ATOM   2740 C CB  . ASN A 1 369 ? 33.309 -40.879 -5.109  1.000 48.366  0 373 ASN A CB  1 ? 
ATOM   2741 C CG  . ASN A 1 369 ? 34.331 -41.956 -4.903  1.000 53.662  0 373 ASN A CG  1 ? 
ATOM   2742 O OD1 . ASN A 1 369 ? 35.010 -42.357 -5.851  1.000 56.970  0 373 ASN A OD1 1 ? 
ATOM   2743 N ND2 . ASN A 1 369 ? 34.470 -42.426 -3.662  1.000 51.267  0 373 ASN A ND2 1 ? 
ATOM   2744 N N   . GLN A 1 370 ? 32.081 -37.983 -5.799  1.000 52.301  0 374 GLN A N   1 ? 
ATOM   2745 C CA  . GLN A 1 370 ? 31.140 -37.162 -6.563  1.000 50.188  0 374 GLN A CA  1 ? 
ATOM   2746 C C   . GLN A 1 370 ? 31.864 -36.081 -7.357  1.000 56.552  0 374 GLN A C   1 ? 
ATOM   2747 O O   . GLN A 1 370 ? 31.612 -35.914 -8.557  1.000 62.526  0 374 GLN A O   1 ? 
ATOM   2748 C CB  . GLN A 1 370 ? 30.098 -36.529 -5.640  1.000 49.932  0 374 GLN A CB  1 ? 
ATOM   2749 C CG  . GLN A 1 370 ? 28.949 -37.446 -5.220  1.000 52.883  0 374 GLN A CG  1 ? 
ATOM   2750 C CD  . GLN A 1 370 ? 27.935 -37.676 -6.324  1.000 56.778  0 374 GLN A CD  1 ? 
ATOM   2751 O OE1 . GLN A 1 370 ? 28.005 -37.062 -7.395  1.000 53.680  0 374 GLN A OE1 1 ? 
ATOM   2752 N NE2 . GLN A 1 370 ? 26.976 -38.565 -6.067  1.000 59.370  0 374 GLN A NE2 1 ? 
ATOM   2753 N N   . VAL A 1 371 ? 32.763 -35.331 -6.704  1.000 54.378  0 375 VAL A N   1 ? 
ATOM   2754 C CA  . VAL A 1 371 ? 33.504 -34.280 -7.401  1.000 51.619  0 375 VAL A CA  1 ? 
ATOM   2755 C C   . VAL A 1 371 ? 34.283 -34.869 -8.561  1.000 60.141  0 375 VAL A C   1 ? 
ATOM   2756 O O   . VAL A 1 371 ? 34.218 -34.372 -9.690  1.000 65.329  0 375 VAL A O   1 ? 
ATOM   2757 C CB  . VAL A 1 371 ? 34.444 -33.536 -6.440  1.000 50.245  0 375 VAL A CB  1 ? 
ATOM   2758 C CG1 . VAL A 1 371 ? 35.248 -32.495 -7.215  1.000 51.230  0 375 VAL A CG1 1 ? 
ATOM   2759 C CG2 . VAL A 1 371 ? 33.672 -32.888 -5.324  1.000 47.943  0 375 VAL A CG2 1 ? 
ATOM   2760 N N   . LEU A 1 372 ? 35.045 -35.933 -8.293  1.000 62.834  0 376 LEU A N   1 ? 
ATOM   2761 C CA  . LEU A 1 372 ? 35.788 -36.609 -9.350  1.000 61.660  0 376 LEU A CA  1 ? 
ATOM   2762 C C   . LEU A 1 372 ? 34.881 -36.943 -10.533 1.000 62.858  0 376 LEU A C   1 ? 
ATOM   2763 O O   . LEU A 1 372 ? 35.207 -36.654 -11.690 1.000 59.099  0 376 LEU A O   1 ? 
ATOM   2764 C CB  . LEU A 1 372 ? 36.445 -37.868 -8.780  1.000 49.019  0 376 LEU A CB  1 ? 
ATOM   2765 C CG  . LEU A 1 372 ? 37.634 -37.487 -7.903  1.000 45.845  0 376 LEU A CG  1 ? 
ATOM   2766 C CD1 . LEU A 1 372 ? 38.273 -38.704 -7.232  1.000 45.021  0 376 LEU A CD1 1 ? 
ATOM   2767 C CD2 . LEU A 1 372 ? 38.650 -36.689 -8.723  1.000 35.291  0 376 LEU A CD2 1 ? 
ATOM   2768 N N   . ALA A 1 373 ? 33.714 -37.523 -10.249 1.000 68.779  0 377 ALA A N   1 ? 
ATOM   2769 C CA  . ALA A 1 373 ? 32.779 -37.876 -11.312 1.000 69.066  0 377 ALA A CA  1 ? 
ATOM   2770 C C   . ALA A 1 373 ? 32.232 -36.642 -12.013 1.000 69.361  0 377 ALA A C   1 ? 
ATOM   2771 O O   . ALA A 1 373 ? 31.858 -36.716 -13.186 1.000 64.687  0 377 ALA A O   1 ? 
ATOM   2772 C CB  . ALA A 1 373 ? 31.629 -38.717 -10.756 1.000 66.747  0 377 ALA A CB  1 ? 
ATOM   2773 N N   . GLN A 1 374 ? 32.161 -35.506 -11.322 1.000 74.040  0 378 GLN A N   1 ? 
ATOM   2774 C CA  . GLN A 1 374 ? 31.718 -34.302 -12.014 1.000 67.769  0 378 GLN A CA  1 ? 
ATOM   2775 C C   . GLN A 1 374 ? 32.833 -33.738 -12.888 1.000 62.589  0 378 GLN A C   1 ? 
ATOM   2776 O O   . GLN A 1 374 ? 32.581 -33.351 -14.033 1.000 69.756  0 378 GLN A O   1 ? 
ATOM   2777 C CB  . GLN A 1 374 ? 31.202 -33.260 -11.015 1.000 61.020  0 378 GLN A CB  1 ? 
ATOM   2778 C CG  . GLN A 1 374 ? 29.913 -33.657 -10.252 1.000 54.159  0 378 GLN A CG  1 ? 
ATOM   2779 C CD  . GLN A 1 374 ? 28.672 -33.734 -11.144 1.000 59.181  0 378 GLN A CD  1 ? 
ATOM   2780 O OE1 . GLN A 1 374 ? 28.127 -34.816 -11.370 1.000 65.734  0 378 GLN A OE1 1 ? 
ATOM   2781 N NE2 . GLN A 1 374 ? 28.224 -32.590 -11.653 1.000 57.349  0 378 GLN A NE2 1 ? 
ATOM   2782 N N   . ILE A 1 375 ? 34.072 -33.709 -12.386 1.000 50.198  0 379 ILE A N   1 ? 
ATOM   2783 C CA  . ILE A 1 375 ? 35.195 -33.303 -13.227 1.000 57.581  0 379 ILE A CA  1 ? 
ATOM   2784 C C   . ILE A 1 375 ? 35.281 -34.196 -14.449 1.000 66.126  0 379 ILE A C   1 ? 
ATOM   2785 O O   . ILE A 1 375 ? 35.642 -33.749 -15.546 1.000 65.797  0 379 ILE A O   1 ? 
ATOM   2786 C CB  . ILE A 1 375 ? 36.516 -33.346 -12.442 1.000 52.591  0 379 ILE A CB  1 ? 
ATOM   2787 C CG1 . ILE A 1 375 ? 36.434 -32.518 -11.164 1.000 47.593  0 379 ILE A CG1 1 ? 
ATOM   2788 C CG2 . ILE A 1 375 ? 37.668 -32.894 -13.337 1.000 52.143  0 379 ILE A CG2 1 ? 
ATOM   2789 C CD1 . ILE A 1 375 ? 37.603 -32.795 -10.221 1.000 48.990  0 379 ILE A CD1 1 ? 
ATOM   2790 N N   . GLU A 1 376 ? 34.958 -35.478 -14.273 1.000 67.163  0 380 GLU A N   1 ? 
ATOM   2791 C CA  . GLU A 1 376 ? 35.091 -36.458 -15.343 1.000 69.277  0 380 GLU A CA  1 ? 
ATOM   2792 C C   . GLU A 1 376 ? 33.922 -36.380 -16.325 1.000 72.730  0 380 GLU A C   1 ? 
ATOM   2793 O O   . GLU A 1 376 ? 34.131 -36.386 -17.545 1.000 68.182  0 380 GLU A O   1 ? 
ATOM   2794 C CB  . GLU A 1 376 ? 35.215 -37.860 -14.742 1.000 68.187  0 380 GLU A CB  1 ? 
ATOM   2795 C CG  . GLU A 1 376 ? 35.103 -38.970 -15.752 1.000 74.135  0 380 GLU A CG  1 ? 
ATOM   2796 C CD  . GLU A 1 376 ? 36.396 -39.190 -16.500 1.000 80.049  0 380 GLU A CD  1 ? 
ATOM   2797 O OE1 . GLU A 1 376 ? 37.448 -38.777 -15.968 1.000 84.665  0 380 GLU A OE1 1 ? 
ATOM   2798 O OE2 . GLU A 1 376 ? 36.353 -39.754 -17.619 1.000 78.878  0 380 GLU A OE2 1 ? 
ATOM   2799 N N   . LEU A 1 377 ? 32.684 -36.320 -15.811 1.000 73.477  0 381 LEU A N   1 ? 
ATOM   2800 C CA  . LEU A 1 377 ? 31.520 -36.128 -16.676 1.000 64.897  0 381 LEU A CA  1 ? 
ATOM   2801 C C   . LEU A 1 377 ? 31.594 -34.799 -17.404 1.000 65.642  0 381 LEU A C   1 ? 
ATOM   2802 O O   . LEU A 1 377 ? 31.130 -34.688 -18.545 1.000 57.923  0 381 LEU A O   1 ? 
ATOM   2803 C CB  . LEU A 1 377 ? 30.216 -36.203 -15.866 1.000 63.068  0 381 LEU A CB  1 ? 
ATOM   2804 C CG  . LEU A 1 377 ? 29.577 -37.559 -15.503 1.000 60.297  0 381 LEU A CG  1 ? 
ATOM   2805 C CD1 . LEU A 1 377 ? 28.334 -37.376 -14.624 1.000 51.390  0 381 LEU A CD1 1 ? 
ATOM   2806 C CD2 . LEU A 1 377 ? 29.224 -38.362 -16.735 1.000 60.276  0 381 LEU A CD2 1 ? 
ATOM   2807 N N   . PHE A 1 378 ? 32.180 -33.781 -16.771 1.000 69.587  0 382 PHE A N   1 ? 
ATOM   2808 C CA  . PHE A 1 378 ? 32.214 -32.468 -17.398 1.000 75.364  0 382 PHE A CA  1 ? 
ATOM   2809 C C   . PHE A 1 378 ? 33.284 -32.370 -18.477 1.000 71.622  0 382 PHE A C   1 ? 
ATOM   2810 O O   . PHE A 1 378 ? 33.125 -31.595 -19.427 1.000 74.272  0 382 PHE A O   1 ? 
ATOM   2811 C CB  . PHE A 1 378 ? 32.426 -31.388 -16.343 1.000 80.260  0 382 PHE A CB  1 ? 
ATOM   2812 C CG  . PHE A 1 378 ? 32.607 -30.022 -16.912 1.000 86.605  0 382 PHE A CG  1 ? 
ATOM   2813 C CD1 . PHE A 1 378 ? 31.562 -29.388 -17.566 1.000 91.500  0 382 PHE A CD1 1 ? 
ATOM   2814 C CD2 . PHE A 1 378 ? 33.826 -29.378 -16.812 1.000 83.178  0 382 PHE A CD2 1 ? 
ATOM   2815 C CE1 . PHE A 1 378 ? 31.730 -28.132 -18.101 1.000 92.358  0 382 PHE A CE1 1 ? 
ATOM   2816 C CE2 . PHE A 1 378 ? 34.000 -28.122 -17.339 1.000 84.894  0 382 PHE A CE2 1 ? 
ATOM   2817 C CZ  . PHE A 1 378 ? 32.952 -27.497 -17.988 1.000 89.655  0 382 PHE A CZ  1 ? 
ATOM   2818 N N   . GLN A 1 379 ? 34.355 -33.156 -18.376 1.000 70.272  0 383 GLN A N   1 ? 
ATOM   2819 C CA  . GLN A 1 379 ? 35.468 -33.029 -19.308 1.000 77.859  0 383 GLN A CA  1 ? 
ATOM   2820 C C   . GLN A 1 379 ? 35.535 -34.118 -20.376 1.000 80.273  0 383 GLN A C   1 ? 
ATOM   2821 O O   . GLN A 1 379 ? 36.181 -33.895 -21.407 1.000 74.927  0 383 GLN A O   1 ? 
ATOM   2822 C CB  . GLN A 1 379 ? 36.794 -32.996 -18.540 1.000 74.275  0 383 GLN A CB  1 ? 
ATOM   2823 C CG  . GLN A 1 379 ? 37.093 -31.640 -17.926 1.000 77.662  0 383 GLN A CG  1 ? 
ATOM   2824 C CD  . GLN A 1 379 ? 38.437 -31.603 -17.226 1.000 84.618  0 383 GLN A CD  1 ? 
ATOM   2825 O OE1 . GLN A 1 379 ? 39.063 -32.640 -17.002 1.000 81.768  0 383 GLN A OE1 1 ? 
ATOM   2826 N NE2 . GLN A 1 379 ? 38.889 -30.404 -16.877 1.000 88.155  0 383 GLN A NE2 1 ? 
ATOM   2827 N N   . ASN A 1 380 ? 34.893 -35.276 -20.172 1.000 86.073  0 384 ASN A N   1 ? 
ATOM   2828 C CA  . ASN A 1 380 ? 35.000 -36.412 -21.095 1.000 88.734  0 384 ASN A CA  1 ? 
ATOM   2829 C C   . ASN A 1 380 ? 33.653 -37.113 -21.289 1.000 87.853  0 384 ASN A C   1 ? 
ATOM   2830 O O   . ASN A 1 380 ? 33.597 -38.340 -21.435 1.000 87.316  0 384 ASN A O   1 ? 
ATOM   2831 C CB  . ASN A 1 380 ? 36.030 -37.436 -20.609 1.000 94.272  0 384 ASN A CB  1 ? 
ATOM   2832 C CG  . ASN A 1 380 ? 37.413 -36.846 -20.408 1.000 100.817 0 384 ASN A CG  1 ? 
ATOM   2833 O OD1 . ASN A 1 380 ? 37.851 -35.971 -21.162 1.000 98.967  0 384 ASN A OD1 1 ? 
ATOM   2834 N ND2 . ASN A 1 380 ? 38.112 -37.325 -19.379 1.000 102.947 0 384 ASN A ND2 1 ? 
ATOM   2835 N N   . SER A 1 381 ? 32.547 -36.354 -21.307 1.000 92.143  0 385 SER A N   1 ? 
ATOM   2836 C CA  . SER A 1 381 ? 31.231 -36.983 -21.456 1.000 91.287  0 385 SER A CA  1 ? 
ATOM   2837 C C   . SER A 1 381 ? 31.040 -37.568 -22.849 1.000 93.719  0 385 SER A C   1 ? 
ATOM   2838 O O   . SER A 1 381 ? 30.256 -38.508 -23.023 1.000 94.648  0 385 SER A O   1 ? 
ATOM   2839 C CB  . SER A 1 381 ? 30.109 -35.986 -21.162 1.000 86.845  0 385 SER A CB  1 ? 
ATOM   2840 O OG  . SER A 1 381 ? 28.851 -36.499 -21.570 1.000 88.774  0 385 SER A OG  1 ? 
ATOM   2841 N N   . SER A 1 382 ? 31.746 -37.025 -23.844 1.000 90.406  0 386 SER A N   1 ? 
ATOM   2842 C CA  . SER A 1 382 ? 31.670 -37.546 -25.202 1.000 88.003  0 386 SER A CA  1 ? 
ATOM   2843 C C   . SER A 1 382 ? 31.974 -39.036 -25.233 1.000 84.018  0 386 SER A C   1 ? 
ATOM   2844 O O   . SER A 1 382 ? 31.378 -39.786 -26.017 1.000 82.368  0 386 SER A O   1 ? 
ATOM   2845 C CB  . SER A 1 382 ? 32.654 -36.788 -26.088 1.000 92.277  0 386 SER A CB  1 ? 
ATOM   2846 O OG  . SER A 1 382 ? 32.728 -35.429 -25.693 1.000 95.464  0 386 SER A OG  1 ? 
ATOM   2847 N N   . GLN A 1 383 ? 32.911 -39.477 -24.386 1.000 82.781  0 387 GLN A N   1 ? 
ATOM   2848 C CA  . GLN A 1 383 ? 33.401 -40.851 -24.413 1.000 85.600  0 387 GLN A CA  1 ? 
ATOM   2849 C C   . GLN A 1 383 ? 32.392 -41.858 -23.870 1.000 85.110  0 387 GLN A C   1 ? 
ATOM   2850 O O   . GLN A 1 383 ? 32.644 -43.065 -23.970 1.000 83.576  0 387 GLN A O   1 ? 
ATOM   2851 C CB  . GLN A 1 383 ? 34.710 -40.947 -23.624 1.000 86.287  0 387 GLN A CB  1 ? 
ATOM   2852 C CG  . GLN A 1 383 ? 35.980 -40.674 -24.435 1.000 92.345  0 387 GLN A CG  1 ? 
ATOM   2853 C CD  . GLN A 1 383 ? 36.346 -39.198 -24.521 1.000 94.317  0 387 GLN A CD  1 ? 
ATOM   2854 O OE1 . GLN A 1 383 ? 35.558 -38.368 -24.986 1.000 95.993  0 387 GLN A OE1 1 ? 
ATOM   2855 N NE2 . GLN A 1 383 ? 37.547 -38.864 -24.061 1.000 87.645  0 387 GLN A NE2 1 ? 
ATOM   2856 N N   . TYR A 1 384 ? 31.263 -41.398 -23.324 1.000 83.715  0 388 TYR A N   1 ? 
ATOM   2857 C CA  . TYR A 1 384 ? 30.296 -42.242 -22.632 1.000 80.081  0 388 TYR A CA  1 ? 
ATOM   2858 C C   . TYR A 1 384 ? 28.965 -42.287 -23.371 1.000 76.014  0 388 TYR A C   1 ? 
ATOM   2859 O O   . TYR A 1 384 ? 28.513 -41.294 -23.955 1.000 76.404  0 388 TYR A O   1 ? 
ATOM   2860 C CB  . TYR A 1 384 ? 30.025 -41.744 -21.207 1.000 77.478  0 388 TYR A CB  1 ? 
ATOM   2861 C CG  . TYR A 1 384 ? 31.164 -41.906 -20.231 1.000 79.094  0 388 TYR A CG  1 ? 
ATOM   2862 C CD1 . TYR A 1 384 ? 32.331 -41.161 -20.363 1.000 81.994  0 388 TYR A CD1 1 ? 
ATOM   2863 C CD2 . TYR A 1 384 ? 31.058 -42.779 -19.151 1.000 75.675  0 388 TYR A CD2 1 ? 
ATOM   2864 C CE1 . TYR A 1 384 ? 33.368 -41.297 -19.459 1.000 81.934  0 388 TYR A CE1 1 ? 
ATOM   2865 C CE2 . TYR A 1 384 ? 32.086 -42.919 -18.242 1.000 69.661  0 388 TYR A CE2 1 ? 
ATOM   2866 C CZ  . TYR A 1 384 ? 33.237 -42.176 -18.401 1.000 74.169  0 388 TYR A CZ  1 ? 
ATOM   2867 O OH  . TYR A 1 384 ? 34.270 -42.304 -17.506 1.000 78.499  0 388 TYR A OH  1 ? 
ATOM   2868 N N   . GLN A 1 385 ? 28.322 -43.438 -23.292 1.000 66.913  0 389 GLN A N   1 ? 
ATOM   2869 C CA  . GLN A 1 385 ? 27.034 -43.638 -23.915 1.000 67.958  0 389 GLN A CA  1 ? 
ATOM   2870 C C   . GLN A 1 385 ? 25.929 -43.470 -22.885 1.000 70.032  0 389 GLN A C   1 ? 
ATOM   2871 O O   . GLN A 1 385 ? 26.151 -42.993 -21.768 1.000 73.609  0 389 GLN A O   1 ? 
ATOM   2872 C CB  . GLN A 1 385 ? 26.994 -45.010 -24.576 1.000 73.656  0 389 GLN A CB  1 ? 
ATOM   2873 C CG  . GLN A 1 385 ? 28.241 -45.317 -25.366 1.000 85.044  0 389 GLN A CG  1 ? 
ATOM   2874 C CD  . GLN A 1 385 ? 28.311 -46.763 -25.784 1.000 93.906  0 389 GLN A CD  1 ? 
ATOM   2875 O OE1 . GLN A 1 385 ? 28.892 -47.594 -25.080 1.000 99.349  0 389 GLN A OE1 1 ? 
ATOM   2876 N NE2 . GLN A 1 385 ? 27.722 -47.079 -26.934 1.000 92.298  0 389 GLN A NE2 1 ? 
ATOM   2877 N N   . ASN A 1 386 ? 24.721 -43.875 -23.257 1.000 73.482  0 390 ASN A N   1 ? 
ATOM   2878 C CA  . ASN A 1 386 ? 23.578 -43.789 -22.356 1.000 76.322  0 390 ASN A CA  1 ? 
ATOM   2879 C C   . ASN A 1 386 ? 23.417 -45.070 -21.541 1.000 69.722  0 390 ASN A C   1 ? 
ATOM   2880 O O   . ASN A 1 386 ? 22.373 -45.723 -21.536 1.000 68.961  0 390 ASN A O   1 ? 
ATOM   2881 C CB  . ASN A 1 386 ? 22.325 -43.453 -23.153 1.000 78.715  0 390 ASN A CB  1 ? 
ATOM   2882 C CG  . ASN A 1 386 ? 22.439 -42.110 -23.866 1.000 82.320  0 390 ASN A CG  1 ? 
ATOM   2883 O OD1 . ASN A 1 386 ? 23.352 -41.328 -23.596 1.000 76.909  0 390 ASN A OD1 1 ? 
ATOM   2884 N ND2 . ASN A 1 386 ? 21.512 -41.841 -24.784 1.000 90.335  0 390 ASN A ND2 1 ? 
ATOM   2885 N N   . GLN A 1 387 ? 24.492 -45.426 -20.838 1.000 63.131  0 391 GLN A N   1 ? 
ATOM   2886 C CA  . GLN A 1 387 ? 24.513 -46.522 -19.881 1.000 63.300  0 391 GLN A CA  1 ? 
ATOM   2887 C C   . GLN A 1 387 ? 25.075 -46.029 -18.548 1.000 66.429  0 391 GLN A C   1 ? 
ATOM   2888 O O   . GLN A 1 387 ? 25.413 -44.850 -18.368 1.000 58.631  0 391 GLN A O   1 ? 
ATOM   2889 C CB  . GLN A 1 387 ? 25.348 -47.701 -20.388 1.000 57.067  0 391 GLN A CB  1 ? 
ATOM   2890 C CG  . GLN A 1 387 ? 24.988 -48.177 -21.767 1.000 60.081  0 391 GLN A CG  1 ? 
ATOM   2891 C CD  . GLN A 1 387 ? 26.192 -48.733 -22.506 1.000 64.979  0 391 GLN A CD  1 ? 
ATOM   2892 O OE1 . GLN A 1 387 ? 27.266 -48.915 -21.925 1.000 64.326  0 391 GLN A OE1 1 ? 
ATOM   2893 N NE2 . GLN A 1 387 ? 26.021 -48.999 -23.795 1.000 69.071  0 391 GLN A NE2 1 ? 
ATOM   2894 N N   . VAL A 1 388 ? 25.189 -46.951 -17.608 1.000 61.934  0 392 VAL A N   1 ? 
ATOM   2895 C CA  . VAL A 1 388 ? 25.736 -46.642 -16.297 1.000 63.484  0 392 VAL A CA  1 ? 
ATOM   2896 C C   . VAL A 1 388 ? 27.171 -47.147 -16.254 1.000 63.150  0 392 VAL A C   1 ? 
ATOM   2897 O O   . VAL A 1 388 ? 27.497 -48.187 -16.845 1.000 63.371  0 392 VAL A O   1 ? 
ATOM   2898 C CB  . VAL A 1 388 ? 24.872 -47.251 -15.171 1.000 63.502  0 392 VAL A CB  1 ? 
ATOM   2899 C CG1 . VAL A 1 388 ? 23.388 -47.010 -15.449 1.000 53.775  0 392 VAL A CG1 1 ? 
ATOM   2900 C CG2 . VAL A 1 388 ? 25.176 -48.730 -14.965 1.000 66.521  0 392 VAL A CG2 1 ? 
ATOM   2901 N N   . TYR A 1 389 ? 28.038 -46.388 -15.582 1.000 63.594  0 393 TYR A N   1 ? 
ATOM   2902 C CA  . TYR A 1 389 ? 29.465 -46.678 -15.489 1.000 60.015  0 393 TYR A CA  1 ? 
ATOM   2903 C C   . TYR A 1 389 ? 29.922 -46.400 -14.063 1.000 62.897  0 393 TYR A C   1 ? 
ATOM   2904 O O   . TYR A 1 389 ? 29.234 -45.718 -13.294 1.000 68.453  0 393 TYR A O   1 ? 
ATOM   2905 C CB  . TYR A 1 389 ? 30.305 -45.823 -16.467 1.000 57.136  0 393 TYR A CB  1 ? 
ATOM   2906 C CG  . TYR A 1 389 ? 29.847 -45.825 -17.916 1.000 51.733  0 393 TYR A CG  1 ? 
ATOM   2907 C CD1 . TYR A 1 389 ? 28.754 -45.061 -18.334 1.000 40.742  0 393 TYR A CD1 1 ? 
ATOM   2908 C CD2 . TYR A 1 389 ? 30.528 -46.580 -18.872 1.000 53.706  0 393 TYR A CD2 1 ? 
ATOM   2909 C CE1 . TYR A 1 389 ? 28.349 -45.069 -19.667 1.000 60.715  0 393 TYR A CE1 1 ? 
ATOM   2910 C CE2 . TYR A 1 389 ? 30.136 -46.593 -20.199 1.000 56.709  0 393 TYR A CE2 1 ? 
ATOM   2911 C CZ  . TYR A 1 389 ? 29.048 -45.842 -20.596 1.000 63.626  0 393 TYR A CZ  1 ? 
ATOM   2912 O OH  . TYR A 1 389 ? 28.683 -45.869 -21.924 1.000 69.264  0 393 TYR A OH  1 ? 
ATOM   2913 N N   . VAL A 1 390 ? 31.092 -46.932 -13.706 1.000 56.194  0 394 VAL A N   1 ? 
ATOM   2914 C CA  . VAL A 1 390 ? 31.711 -46.595 -12.432 1.000 56.012  0 394 VAL A CA  1 ? 
ATOM   2915 C C   . VAL A 1 390 ? 33.069 -45.975 -12.722 1.000 54.643  0 394 VAL A C   1 ? 
ATOM   2916 O O   . VAL A 1 390 ? 33.635 -46.128 -13.809 1.000 44.171  0 394 VAL A O   1 ? 
ATOM   2917 C CB  . VAL A 1 390 ? 31.856 -47.796 -11.449 1.000 50.838  0 394 VAL A CB  1 ? 
ATOM   2918 C CG1 . VAL A 1 390 ? 30.508 -48.152 -10.783 1.000 41.908  0 394 VAL A CG1 1 ? 
ATOM   2919 C CG2 . VAL A 1 390 ? 32.495 -49.007 -12.117 1.000 42.318  0 394 VAL A CG2 1 ? 
ATOM   2920 N N   . LEU A 1 391 ? 33.584 -45.268 -11.720 1.000 58.923  0 395 LEU A N   1 ? 
ATOM   2921 C CA  . LEU A 1 391 ? 34.885 -44.634 -11.820 1.000 58.165  0 395 LEU A CA  1 ? 
ATOM   2922 C C   . LEU A 1 391 ? 36.008 -45.680 -11.839 1.000 61.042  0 395 LEU A C   1 ? 
ATOM   2923 O O   . LEU A 1 391 ? 35.858 -46.778 -11.289 1.000 61.936  0 395 LEU A O   1 ? 
ATOM   2924 C CB  . LEU A 1 391 ? 35.076 -43.673 -10.648 1.000 47.961  0 395 LEU A CB  1 ? 
ATOM   2925 C CG  . LEU A 1 391 ? 34.346 -42.338 -10.792 1.000 50.003  0 395 LEU A CG  1 ? 
ATOM   2926 C CD1 . LEU A 1 391 ? 34.369 -41.521 -9.486  1.000 44.263  0 395 LEU A CD1 1 ? 
ATOM   2927 C CD2 . LEU A 1 391 ? 34.929 -41.540 -11.958 1.000 51.080  0 395 LEU A CD2 1 ? 
ATOM   2928 N N   . PRO A 1 392 ? 37.141 -45.362 -12.479 1.000 56.830  0 396 PRO A N   1 ? 
ATOM   2929 C CA  . PRO A 1 392 ? 38.302 -46.271 -12.460 1.000 53.601  0 396 PRO A CA  1 ? 
ATOM   2930 C C   . PRO A 1 392 ? 38.831 -46.559 -11.056 1.000 48.927  0 396 PRO A C   1 ? 
ATOM   2931 O O   . PRO A 1 392 ? 38.725 -45.739 -10.139 1.000 42.521  0 396 PRO A O   1 ? 
ATOM   2932 C CB  . PRO A 1 392 ? 39.344 -45.518 -13.294 1.000 52.067  0 396 PRO A CB  1 ? 
ATOM   2933 C CG  . PRO A 1 392 ? 38.528 -44.671 -14.217 1.000 50.296  0 396 PRO A CG  1 ? 
ATOM   2934 C CD  . PRO A 1 392 ? 37.331 -44.243 -13.419 1.000 53.433  0 396 PRO A CD  1 ? 
ATOM   2935 N N   . LYS A 1 393 ? 39.429 -47.749 -10.904 1.000 42.429  0 397 LYS A N   1 ? 
ATOM   2936 C CA  . LYS A 1 393 ? 39.951 -48.150 -9.602  1.000 42.358  0 397 LYS A CA  1 ? 
ATOM   2937 C C   . LYS A 1 393 ? 41.024 -47.188 -9.101  1.000 43.834  0 397 LYS A C   1 ? 
ATOM   2938 O O   . LYS A 1 393 ? 41.134 -46.954 -7.885  1.000 34.362  0 397 LYS A O   1 ? 
ATOM   2939 C CB  . LYS A 1 393 ? 40.505 -49.578 -9.656  1.000 34.020  0 397 LYS A CB  1 ? 
ATOM   2940 C CG  . LYS A 1 393 ? 40.927 -50.095 -8.278  1.000 30.222  0 397 LYS A CG  1 ? 
ATOM   2941 C CD  . LYS A 1 393 ? 41.206 -51.584 -8.271  1.000 38.165  0 397 LYS A CD  1 ? 
ATOM   2942 C CE  . LYS A 1 393 ? 39.914 -52.387 -8.382  1.000 40.731  0 397 LYS A CE  1 ? 
ATOM   2943 N NZ  . LYS A 1 393 ? 38.932 -51.895 -7.386  1.000 35.223  0 397 LYS A NZ  1 ? 
ATOM   2944 N N   . VAL A 1 394 ? 41.806 -46.606 -10.013 1.000 40.247  0 398 VAL A N   1 ? 
ATOM   2945 C CA  . VAL A 1 394 ? 42.907 -45.762 -9.572  1.000 38.889  0 398 VAL A CA  1 ? 
ATOM   2946 C C   . VAL A 1 394 ? 42.380 -44.478 -8.944  1.000 41.502  0 398 VAL A C   1 ? 
ATOM   2947 O O   . VAL A 1 394 ? 43.045 -43.881 -8.083  1.000 40.700  0 398 VAL A O   1 ? 
ATOM   2948 C CB  . VAL A 1 394 ? 43.873 -45.503 -10.742 1.000 46.748  0 398 VAL A CB  1 ? 
ATOM   2949 C CG1 . VAL A 1 394 ? 43.324 -44.418 -11.691 1.000 32.633  0 398 VAL A CG1 1 ? 
ATOM   2950 C CG2 . VAL A 1 394 ? 45.276 -45.169 -10.208 1.000 45.737  0 398 VAL A CG2 1 ? 
ATOM   2951 N N   . LEU A 1 395 ? 41.166 -44.055 -9.319  1.000 43.147  0 399 LEU A N   1 ? 
ATOM   2952 C CA  . LEU A 1 395 ? 40.524 -42.922 -8.649  1.000 48.543  0 399 LEU A CA  1 ? 
ATOM   2953 C C   . LEU A 1 395 ? 39.947 -43.339 -7.305  1.000 43.542  0 399 LEU A C   1 ? 
ATOM   2954 O O   . LEU A 1 395 ? 40.055 -42.607 -6.315  1.000 42.634  0 399 LEU A O   1 ? 
ATOM   2955 C CB  . LEU A 1 395 ? 39.430 -42.322 -9.537  1.000 46.719  0 399 LEU A CB  1 ? 
ATOM   2956 C CG  . LEU A 1 395 ? 39.953 -41.334 -10.592 1.000 47.748  0 399 LEU A CG  1 ? 
ATOM   2957 C CD1 . LEU A 1 395 ? 38.838 -40.826 -11.483 1.000 39.923  0 399 LEU A CD1 1 ? 
ATOM   2958 C CD2 . LEU A 1 395 ? 40.696 -40.180 -9.928  1.000 43.871  0 399 LEU A CD2 1 ? 
ATOM   2959 N N   . ASP A 1 396 ? 39.329 -44.514 -7.268  1.000 37.570  0 400 ASP A N   1 ? 
ATOM   2960 C CA  . ASP A 1 396 ? 38.884 -45.093 -6.013  1.000 37.623  0 400 ASP A CA  1 ? 
ATOM   2961 C C   . ASP A 1 396 ? 40.024 -45.136 -5.003  1.000 39.218  0 400 ASP A C   1 ? 
ATOM   2962 O O   . ASP A 1 396 ? 39.857 -44.756 -3.835  1.000 38.357  0 400 ASP A O   1 ? 
ATOM   2963 C CB  . ASP A 1 396 ? 38.340 -46.496 -6.283  1.000 40.460  0 400 ASP A CB  1 ? 
ATOM   2964 C CG  . ASP A 1 396 ? 37.084 -46.798 -5.514  1.000 47.092  0 400 ASP A CG  1 ? 
ATOM   2965 O OD1 . ASP A 1 396 ? 36.736 -46.035 -4.580  1.000 54.770  0 400 ASP A OD1 1 ? 
ATOM   2966 O OD2 . ASP A 1 396 ? 36.446 -47.812 -5.856  1.000 40.652  0 400 ASP A OD2 1 ? 
ATOM   2967 N N   . GLU A 1 397 ? 41.200 -45.601 -5.444  1.000 33.433  0 401 GLU A N   1 ? 
ATOM   2968 C CA  . GLU A 1 397 ? 42.349 -45.651 -4.547  1.000 34.425  0 401 GLU A CA  1 ? 
ATOM   2969 C C   . GLU A 1 397 ? 42.792 -44.252 -4.138  1.000 32.809  0 401 GLU A C   1 ? 
ATOM   2970 O O   . GLU A 1 397 ? 43.082 -44.016 -2.963  1.000 34.583  0 401 GLU A O   1 ? 
ATOM   2971 C CB  . GLU A 1 397 ? 43.489 -46.437 -5.199  1.000 30.325  0 401 GLU A CB  1 ? 
ATOM   2972 C CG  . GLU A 1 397 ? 43.081 -47.863 -5.502  1.000 30.891  0 401 GLU A CG  1 ? 
ATOM   2973 C CD  . GLU A 1 397 ? 44.190 -48.717 -6.077  1.000 46.242  0 401 GLU A CD  1 ? 
ATOM   2974 O OE1 . GLU A 1 397 ? 44.043 -49.959 -6.055  1.000 49.666  0 401 GLU A OE1 1 ? 
ATOM   2975 O OE2 . GLU A 1 397 ? 45.201 -48.162 -6.557  1.000 53.296  0 401 GLU A OE2 1 ? 
ATOM   2976 N N   . LYS A 1 398 ? 42.821 -43.304 -5.085  1.000 33.870  0 402 LYS A N   1 ? 
ATOM   2977 C CA  . LYS A 1 398 ? 43.145 -41.922 -4.744  1.000 34.749  0 402 LYS A CA  1 ? 
ATOM   2978 C C   . LYS A 1 398 ? 42.198 -41.373 -3.679  1.000 35.307  0 402 LYS A C   1 ? 
ATOM   2979 O O   . LYS A 1 398 ? 42.636 -40.709 -2.734  1.000 34.883  0 402 LYS A O   1 ? 
ATOM   2980 C CB  . LYS A 1 398 ? 43.110 -41.047 -5.998  1.000 42.137  0 402 LYS A CB  1 ? 
ATOM   2981 C CG  . LYS A 1 398 ? 43.347 -39.552 -5.754  1.000 37.018  0 402 LYS A CG  1 ? 
ATOM   2982 C CD  . LYS A 1 398 ? 42.729 -38.726 -6.882  1.000 42.376  0 402 LYS A CD  1 ? 
ATOM   2983 C CE  . LYS A 1 398 ? 43.248 -37.280 -6.931  1.000 44.742  0 402 LYS A CE  1 ? 
ATOM   2984 N NZ  . LYS A 1 398 ? 44.654 -37.189 -7.441  1.000 44.432  0 402 LYS A NZ  1 ? 
ATOM   2985 N N   . VAL A 1 399 ? 40.902 -41.658 -3.794  1.000 33.454  0 403 VAL A N   1 ? 
ATOM   2986 C CA  . VAL A 1 399 ? 39.966 -41.192 -2.774  1.000 35.544  0 403 VAL A CA  1 ? 
ATOM   2987 C C   . VAL A 1 399 ? 40.379 -41.701 -1.399  1.000 37.268  0 403 VAL A C   1 ? 
ATOM   2988 O O   . VAL A 1 399 ? 40.474 -40.933 -0.434  1.000 38.560  0 403 VAL A O   1 ? 
ATOM   2989 C CB  . VAL A 1 399 ? 38.532 -41.621 -3.112  1.000 28.193  0 403 VAL A CB  1 ? 
ATOM   2990 C CG1 . VAL A 1 399 ? 37.672 -41.466 -1.910  1.000 27.659  0 403 VAL A CG1 1 ? 
ATOM   2991 C CG2 . VAL A 1 399 ? 37.994 -40.792 -4.257  1.000 37.939  0 403 VAL A CG2 1 ? 
ATOM   2992 N N   . ALA A 1 400 ? 40.614 -43.009 -1.286  1.000 34.862  0 404 ALA A N   1 ? 
ATOM   2993 C CA  . ALA A 1 400 ? 41.003 -43.569 0.003   1.000 35.660  0 404 ALA A CA  1 ? 
ATOM   2994 C C   . ALA A 1 400 ? 42.307 -42.951 0.482   1.000 37.152  0 404 ALA A C   1 ? 
ATOM   2995 O O   . ALA A 1 400 ? 42.446 -42.594 1.663   1.000 30.414  0 404 ALA A O   1 ? 
ATOM   2996 C CB  . ALA A 1 400 ? 41.132 -45.087 -0.107  1.000 25.614  0 404 ALA A CB  1 ? 
ATOM   2997 N N   . ARG A 1 401 ? 43.256 -42.783 -0.442  1.000 32.743  0 405 ARG A N   1 ? 
ATOM   2998 C CA  . ARG A 1 401 ? 44.557 -42.218 -0.115  1.000 35.199  0 405 ARG A CA  1 ? 
ATOM   2999 C C   . ARG A 1 401 ? 44.425 -40.827 0.494   1.000 39.323  0 405 ARG A C   1 ? 
ATOM   3000 O O   . ARG A 1 401 ? 45.188 -40.461 1.397   1.000 39.157  0 405 ARG A O   1 ? 
ATOM   3001 C CB  . ARG A 1 401 ? 45.427 -42.175 -1.372  1.000 29.438  0 405 ARG A CB  1 ? 
ATOM   3002 C CG  . ARG A 1 401 ? 46.775 -42.836 -1.218  1.000 45.087  0 405 ARG A CG  1 ? 
ATOM   3003 C CD  . ARG A 1 401 ? 47.705 -42.598 -2.413  1.000 44.103  0 405 ARG A CD  1 ? 
ATOM   3004 N NE  . ARG A 1 401 ? 47.548 -43.631 -3.437  1.000 50.914  0 405 ARG A NE  1 ? 
ATOM   3005 C CZ  . ARG A 1 401 ? 48.269 -44.752 -3.493  1.000 50.488  0 405 ARG A CZ  1 ? 
ATOM   3006 N NH1 . ARG A 1 401 ? 49.223 -44.989 -2.596  1.000 50.161  0 405 ARG A NH1 1 ? 
ATOM   3007 N NH2 . ARG A 1 401 ? 48.043 -45.637 -4.455  1.000 44.869  0 405 ARG A NH2 1 ? 
ATOM   3008 N N   . LEU A 1 402 ? 43.465 -40.033 0.014   1.000 33.307  0 406 LEU A N   1 ? 
ATOM   3009 C CA  . LEU A 1 402 ? 43.309 -38.692 0.551   1.000 33.293  0 406 LEU A CA  1 ? 
ATOM   3010 C C   . LEU A 1 402 ? 42.783 -38.689 1.979   1.000 40.642  0 406 LEU A C   1 ? 
ATOM   3011 O O   . LEU A 1 402 ? 42.882 -37.654 2.654   1.000 38.705  0 406 LEU A O   1 ? 
ATOM   3012 C CB  . LEU A 1 402 ? 42.388 -37.879 -0.349  1.000 34.380  0 406 LEU A CB  1 ? 
ATOM   3013 C CG  . LEU A 1 402 ? 43.054 -37.626 -1.692  1.000 42.097  0 406 LEU A CG  1 ? 
ATOM   3014 C CD1 . LEU A 1 402 ? 42.077 -36.986 -2.679  1.000 37.502  0 406 LEU A CD1 1 ? 
ATOM   3015 C CD2 . LEU A 1 402 ? 44.335 -36.792 -1.503  1.000 28.377  0 406 LEU A CD2 1 ? 
ATOM   3016 N N   . HIS A 1 403 ? 42.245 -39.818 2.459   1.000 30.412  0 407 HIS A N   1 ? 
ATOM   3017 C CA  . HIS A 1 403 ? 41.668 -39.872 3.790   1.000 26.761  0 407 HIS A CA  1 ? 
ATOM   3018 C C   . HIS A 1 403 ? 42.544 -40.587 4.796   1.000 26.911  0 407 HIS A C   1 ? 
ATOM   3019 O O   . HIS A 1 403 ? 42.230 -40.566 5.991   1.000 32.114  0 407 HIS A O   1 ? 
ATOM   3020 C CB  . HIS A 1 403 ? 40.276 -40.517 3.732   1.000 24.887  0 407 HIS A CB  1 ? 
ATOM   3021 C CG  . HIS A 1 403 ? 39.318 -39.720 2.907   1.000 31.701  0 407 HIS A CG  1 ? 
ATOM   3022 N ND1 . HIS A 1 403 ? 39.326 -39.752 1.526   1.000 29.293  0 407 HIS A ND1 1 ? 
ATOM   3023 C CD2 . HIS A 1 403 ? 38.400 -38.789 3.258   1.000 32.128  0 407 HIS A CD2 1 ? 
ATOM   3024 C CE1 . HIS A 1 403 ? 38.412 -38.917 1.064   1.000 33.380  0 407 HIS A CE1 1 ? 
ATOM   3025 N NE2 . HIS A 1 403 ? 37.841 -38.313 2.094   1.000 33.154  0 407 HIS A NE2 1 ? 
ATOM   3026 N N   . LEU A 1 404 ? 43.645 -41.190 4.359   1.000 31.567  0 408 LEU A N   1 ? 
ATOM   3027 C CA  . LEU A 1 404 ? 44.473 -41.930 5.302   1.000 29.356  0 408 LEU A CA  1 ? 
ATOM   3028 C C   . LEU A 1 404 ? 45.122 -40.998 6.311   1.000 29.425  0 408 LEU A C   1 ? 
ATOM   3029 O O   . LEU A 1 404 ? 45.256 -41.355 7.486   1.000 29.632  0 408 LEU A O   1 ? 
ATOM   3030 C CB  . LEU A 1 404 ? 45.527 -42.739 4.550   1.000 32.159  0 408 LEU A CB  1 ? 
ATOM   3031 C CG  . LEU A 1 404 ? 44.943 -43.820 3.639   1.000 37.799  0 408 LEU A CG  1 ? 
ATOM   3032 C CD1 . LEU A 1 404 ? 46.021 -44.498 2.765   1.000 36.415  0 408 LEU A CD1 1 ? 
ATOM   3033 C CD2 . LEU A 1 404 ? 44.163 -44.830 4.479   1.000 28.014  0 408 LEU A CD2 1 ? 
ATOM   3034 N N   . GLY A 1 405 ? 45.493 -39.793 5.882   1.000 32.822  0 409 GLY A N   1 ? 
ATOM   3035 C CA  . GLY A 1 405 ? 46.224 -38.905 6.764   1.000 27.435  0 409 GLY A CA  1 ? 
ATOM   3036 C C   . GLY A 1 405 ? 45.411 -38.480 7.968   1.000 30.988  0 409 GLY A C   1 ? 
ATOM   3037 O O   . GLY A 1 405 ? 45.918 -38.462 9.092   1.000 23.403  0 409 GLY A O   1 ? 
ATOM   3038 N N   . ARG A 1 406 ? 44.137 -38.137 7.750   1.000 26.298  0 410 ARG A N   1 ? 
ATOM   3039 C CA  . ARG A 1 406 ? 43.309 -37.636 8.845   1.000 31.441  0 410 ARG A CA  1 ? 
ATOM   3040 C C   . ARG A 1 406 ? 43.283 -38.611 10.018  1.000 29.869  0 410 ARG A C   1 ? 
ATOM   3041 O O   . ARG A 1 406 ? 43.380 -38.196 11.178  1.000 38.028  0 410 ARG A O   1 ? 
ATOM   3042 C CB  . ARG A 1 406 ? 41.888 -37.349 8.357   1.000 23.748  0 410 ARG A CB  1 ? 
ATOM   3043 C CG  . ARG A 1 406 ? 40.920 -36.946 9.488   1.000 29.140  0 410 ARG A CG  1 ? 
ATOM   3044 C CD  . ARG A 1 406 ? 41.424 -35.726 10.225  1.000 26.343  0 410 ARG A CD  1 ? 
ATOM   3045 N NE  . ARG A 1 406 ? 40.680 -35.427 11.447  1.000 33.338  0 410 ARG A NE  1 ? 
ATOM   3046 C CZ  . ARG A 1 406 ? 41.018 -35.830 12.675  1.000 29.440  0 410 ARG A CZ  1 ? 
ATOM   3047 N NH1 . ARG A 1 406 ? 42.091 -36.587 12.886  1.000 23.845  0 410 ARG A NH1 1 ? 
ATOM   3048 N NH2 . ARG A 1 406 ? 40.275 -35.471 13.706  1.000 28.730  0 410 ARG A NH2 1 ? 
ATOM   3049 N N   . ILE A 1 407 ? 43.187 -39.911 9.742   1.000 29.767  0 411 ILE A N   1 ? 
ATOM   3050 C CA  . ILE A 1 407 ? 43.069 -40.915 10.799  1.000 29.719  0 411 ILE A CA  1 ? 
ATOM   3051 C C   . ILE A 1 407 ? 44.383 -41.646 11.054  1.000 27.811  0 411 ILE A C   1 ? 
ATOM   3052 O O   . ILE A 1 407 ? 44.379 -42.706 11.689  1.000 27.430  0 411 ILE A O   1 ? 
ATOM   3053 C CB  . ILE A 1 407 ? 41.945 -41.913 10.499  1.000 24.424  0 411 ILE A CB  1 ? 
ATOM   3054 C CG1 . ILE A 1 407 ? 42.107 -42.525 9.107   1.000 31.914  0 411 ILE A CG1 1 ? 
ATOM   3055 C CG2 . ILE A 1 407 ? 40.592 -41.230 10.599  1.000 23.542  0 411 ILE A CG2 1 ? 
ATOM   3056 C CD1 . ILE A 1 407 ? 40.896 -43.354 8.733   1.000 35.481  0 411 ILE A CD1 1 ? 
ATOM   3057 N N   . GLY A 1 408 ? 45.501 -41.111 10.565  1.000 28.185  0 412 GLY A N   1 ? 
ATOM   3058 C CA  . GLY A 1 408 ? 46.833 -41.599 10.922  1.000 22.358  0 412 GLY A CA  1 ? 
ATOM   3059 C C   . GLY A 1 408 ? 47.168 -43.011 10.488  1.000 31.438  0 412 GLY A C   1 ? 
ATOM   3060 O O   . GLY A 1 408 ? 47.847 -43.737 11.226  1.000 37.068  0 412 GLY A O   1 ? 
ATOM   3061 N N   . ALA A 1 409 ? 46.695 -43.430 9.313   1.000 26.369  0 413 ALA A N   1 ? 
ATOM   3062 C CA  . ALA A 1 409 ? 47.046 -44.730 8.754   1.000 22.421  0 413 ALA A CA  1 ? 
ATOM   3063 C C   . ALA A 1 409 ? 48.222 -44.556 7.807   1.000 28.975  0 413 ALA A C   1 ? 
ATOM   3064 O O   . ALA A 1 409 ? 48.156 -43.741 6.885   1.000 33.651  0 413 ALA A O   1 ? 
ATOM   3065 C CB  . ALA A 1 409 ? 45.861 -45.350 8.026   1.000 26.601  0 413 ALA A CB  1 ? 
ATOM   3066 N N   . LYS A 1 410 ? 49.298 -45.299 8.049   1.000 22.734  0 414 LYS A N   1 ? 
ATOM   3067 C CA  . LYS A 1 410 ? 50.520 -45.209 7.262   1.000 24.090  0 414 LYS A CA  1 ? 
ATOM   3068 C C   . LYS A 1 410 ? 50.591 -46.382 6.292   1.000 32.957  0 414 LYS A C   1 ? 
ATOM   3069 O O   . LYS A 1 410 ? 50.549 -47.549 6.709   1.000 30.630  0 414 LYS A O   1 ? 
ATOM   3070 C CB  . LYS A 1 410 ? 51.747 -45.196 8.164   1.000 26.293  0 414 LYS A CB  1 ? 
ATOM   3071 C CG  . LYS A 1 410 ? 53.046 -44.810 7.459   1.000 40.302  0 414 LYS A CG  1 ? 
ATOM   3072 C CD  . LYS A 1 410 ? 54.220 -44.653 8.439   1.000 35.181  0 414 LYS A CD  1 ? 
ATOM   3073 C CE  . LYS A 1 410 ? 55.504 -44.328 7.698   1.000 35.473  0 414 LYS A CE  1 ? 
ATOM   3074 N NZ  . LYS A 1 410 ? 56.692 -44.830 8.425   1.000 48.332  0 414 LYS A NZ  1 ? 
ATOM   3075 N N   . LEU A 1 411 ? 50.740 -46.059 5.007   1.000 23.703  0 415 LEU A N   1 ? 
ATOM   3076 C CA  . LEU A 1 411 ? 50.779 -47.034 3.931   1.000 23.898  0 415 LEU A CA  1 ? 
ATOM   3077 C C   . LEU A 1 411 ? 52.182 -47.601 3.773   1.000 26.108  0 415 LEU A C   1 ? 
ATOM   3078 O O   . LEU A 1 411 ? 53.167 -46.855 3.771   1.000 39.455  0 415 LEU A O   1 ? 
ATOM   3079 C CB  . LEU A 1 411 ? 50.338 -46.359 2.637   1.000 29.138  0 415 LEU A CB  1 ? 
ATOM   3080 C CG  . LEU A 1 411 ? 49.470 -47.038 1.585   1.000 35.370  0 415 LEU A CG  1 ? 
ATOM   3081 C CD1 . LEU A 1 411 ? 48.206 -47.613 2.192   1.000 34.417  0 415 LEU A CD1 1 ? 
ATOM   3082 C CD2 . LEU A 1 411 ? 49.143 -46.035 0.481   1.000 25.550  0 415 LEU A CD2 1 ? 
ATOM   3083 N N   . THR A 1 412 ? 52.272 -48.919 3.634   1.000 31.122  0 416 THR A N   1 ? 
ATOM   3084 C CA  . THR A 1 412 ? 53.515 -49.583 3.257   1.000 29.064  0 416 THR A CA  1 ? 
ATOM   3085 C C   . THR A 1 412 ? 53.770 -49.424 1.753   1.000 32.975  0 416 THR A C   1 ? 
ATOM   3086 O O   . THR A 1 412 ? 52.836 -49.385 0.939   1.000 38.557  0 416 THR A O   1 ? 
ATOM   3087 C CB  . THR A 1 412 ? 53.445 -51.064 3.651   1.000 23.721  0 416 THR A CB  1 ? 
ATOM   3088 O OG1 . THR A 1 412 ? 53.352 -51.159 5.073   1.000 33.296  0 416 THR A OG1 1 ? 
ATOM   3089 C CG2 . THR A 1 412 ? 54.679 -51.826 3.210   1.000 24.148  0 416 THR A CG2 1 ? 
ATOM   3090 N N   . GLN A 1 413 ? 55.041 -49.304 1.380   1.000 28.280  0 417 GLN A N   1 ? 
ATOM   3091 C CA  . GLN A 1 413 ? 55.408 -49.118 -0.022  1.000 37.149  0 417 GLN A CA  1 ? 
ATOM   3092 C C   . GLN A 1 413 ? 55.955 -50.416 -0.611  1.000 36.836  0 417 GLN A C   1 ? 
ATOM   3093 O O   . GLN A 1 413 ? 56.882 -51.022 -0.053  1.000 34.807  0 417 GLN A O   1 ? 
ATOM   3094 C CB  . GLN A 1 413 ? 56.434 -47.989 -0.173  1.000 43.637  0 417 GLN A CB  1 ? 
ATOM   3095 C CG  . GLN A 1 413 ? 55.870 -46.584 0.074   1.000 52.551  0 417 GLN A CG  1 ? 
ATOM   3096 C CD  . GLN A 1 413 ? 54.695 -46.245 -0.844  1.000 65.050  0 417 GLN A CD  1 ? 
ATOM   3097 O OE1 . GLN A 1 413 ? 54.776 -46.408 -2.064  1.000 69.456  0 417 GLN A OE1 1 ? 
ATOM   3098 N NE2 . GLN A 1 413 ? 53.590 -45.781 -0.254  1.000 67.019  0 417 GLN A NE2 1 ? 
ATOM   3099 N N   . LEU A 1 414 ? 55.387 -50.840 -1.739  1.000 29.911  0 418 LEU A N   1 ? 
ATOM   3100 C CA  . LEU A 1 414 ? 55.906 -52.021 -2.421  1.000 27.503  0 418 LEU A CA  1 ? 
ATOM   3101 C C   . LEU A 1 414 ? 57.299 -51.750 -2.989  1.000 31.830  0 418 LEU A C   1 ? 
ATOM   3102 O O   . LEU A 1 414 ? 57.566 -50.684 -3.551  1.000 27.451  0 418 LEU A O   1 ? 
ATOM   3103 C CB  . LEU A 1 414 ? 54.978 -52.446 -3.552  1.000 32.820  0 418 LEU A CB  1 ? 
ATOM   3104 C CG  . LEU A 1 414 ? 53.603 -53.067 -3.262  1.000 38.423  0 418 LEU A CG  1 ? 
ATOM   3105 C CD1 . LEU A 1 414 ? 52.728 -52.971 -4.507  1.000 29.688  0 418 LEU A CD1 1 ? 
ATOM   3106 C CD2 . LEU A 1 414 ? 53.721 -54.520 -2.796  1.000 31.591  0 418 LEU A CD2 1 ? 
ATOM   3107 N N   . SER A 1 415 ? 58.190 -52.721 -2.838  1.000 27.724  0 419 SER A N   1 ? 
ATOM   3108 C CA  . SER A 1 415 ? 59.435 -52.704 -3.591  1.000 27.501  0 419 SER A CA  1 ? 
ATOM   3109 C C   . SER A 1 415 ? 59.166 -53.145 -5.023  1.000 28.003  0 419 SER A C   1 ? 
ATOM   3110 O O   . SER A 1 415 ? 58.115 -53.713 -5.330  1.000 30.722  0 419 SER A O   1 ? 
ATOM   3111 C CB  . SER A 1 415 ? 60.461 -53.620 -2.939  1.000 27.311  0 419 SER A CB  1 ? 
ATOM   3112 O OG  . SER A 1 415 ? 60.068 -54.977 -3.065  1.000 32.901  0 419 SER A OG  1 ? 
ATOM   3113 N N   . ASN A 1 416 ? 60.115 -52.854 -5.908  1.000 28.751  0 420 ASN A N   1 ? 
ATOM   3114 C CA  . ASN A 1 416 ? 59.977 -53.273 -7.301  1.000 29.332  0 420 ASN A CA  1 ? 
ATOM   3115 C C   . ASN A 1 416 ? 59.628 -54.747 -7.393  1.000 30.938  0 420 ASN A C   1 ? 
ATOM   3116 O O   . ASN A 1 416 ? 58.758 -55.141 -8.177  1.000 36.775  0 420 ASN A O   1 ? 
ATOM   3117 C CB  . ASN A 1 416 ? 61.279 -53.021 -8.091  1.000 33.083  0 420 ASN A CB  1 ? 
ATOM   3118 C CG  . ASN A 1 416 ? 61.529 -51.556 -8.398  1.000 30.788  0 420 ASN A CG  1 ? 
ATOM   3119 O OD1 . ASN A 1 416 ? 60.654 -50.708 -8.257  1.000 52.622  0 420 ASN A OD1 1 ? 
ATOM   3120 N ND2 . ASN A 1 416 ? 62.735 -51.258 -8.838  1.000 48.898  0 420 ASN A ND2 1 ? 
ATOM   3121 N N   . GLU A 1 417 ? 60.308 -55.582 -6.604  1.000 35.249  0 421 GLU A N   1 ? 
ATOM   3122 C CA  . GLU A 1 417 ? 60.146 -57.021 -6.746  1.000 33.662  0 421 GLU A CA  1 ? 
ATOM   3123 C C   . GLU A 1 417 ? 58.839 -57.489 -6.149  1.000 31.201  0 421 GLU A C   1 ? 
ATOM   3124 O O   . GLU A 1 417 ? 58.218 -58.410 -6.693  1.000 36.489  0 421 GLU A O   1 ? 
ATOM   3125 C CB  . GLU A 1 417 ? 61.333 -57.768 -6.118  1.000 35.865  0 421 GLU A CB  1 ? 
ATOM   3126 C CG  . GLU A 1 417 ? 61.332 -57.821 -4.605  1.000 44.268  0 421 GLU A CG  1 ? 
ATOM   3127 C CD  . GLU A 1 417 ? 62.569 -58.499 -4.024  1.000 45.661  0 421 GLU A CD  1 ? 
ATOM   3128 O OE1 . GLU A 1 417 ? 62.778 -58.374 -2.795  1.000 48.335  0 421 GLU A OE1 1 ? 
ATOM   3129 O OE2 . GLU A 1 417 ? 63.327 -59.154 -4.779  1.000 43.121  0 421 GLU A OE2 1 ? 
ATOM   3130 N N   . GLN A 1 418 ? 58.404 -56.864 -5.047  1.000 30.751  0 422 GLN A N   1 ? 
ATOM   3131 C CA  . GLN A 1 418 ? 57.093 -57.174 -4.484  1.000 33.141  0 422 GLN A CA  1 ? 
ATOM   3132 C C   . GLN A 1 418 ? 55.983 -56.815 -5.460  1.000 33.822  0 422 GLN A C   1 ? 
ATOM   3133 O O   . GLN A 1 418 ? 55.010 -57.563 -5.618  1.000 38.868  0 422 GLN A O   1 ? 
ATOM   3134 C CB  . GLN A 1 418 ? 56.916 -56.434 -3.166  1.000 30.346  0 422 GLN A CB  1 ? 
ATOM   3135 C CG  . GLN A 1 418 ? 57.562 -57.141 -2.021  1.000 30.367  0 422 GLN A CG  1 ? 
ATOM   3136 C CD  . GLN A 1 418 ? 57.792 -56.227 -0.852  1.000 31.156  0 422 GLN A CD  1 ? 
ATOM   3137 O OE1 . GLN A 1 418 ? 57.708 -55.012 -0.983  1.000 38.262  0 422 GLN A OE1 1 ? 
ATOM   3138 N NE2 . GLN A 1 418 ? 58.088 -56.806 0.303   1.000 24.942  0 422 GLN A NE2 1 ? 
ATOM   3139 N N   . ALA A 1 419 ? 56.126 -55.674 -6.131  1.000 30.077  0 423 ALA A N   1 ? 
ATOM   3140 C CA  . ALA A 1 419 ? 55.173 -55.279 -7.149  1.000 27.803  0 423 ALA A CA  1 ? 
ATOM   3141 C C   . ALA A 1 419 ? 55.117 -56.313 -8.268  1.000 28.188  0 423 ALA A C   1 ? 
ATOM   3142 O O   . ALA A 1 419 ? 54.035 -56.749 -8.671  1.000 41.423  0 423 ALA A O   1 ? 
ATOM   3143 C CB  . ALA A 1 419 ? 55.547 -53.893 -7.674  1.000 28.427  0 423 ALA A CB  1 ? 
ATOM   3144 N N   . ASP A 1 420 ? 56.275 -56.731 -8.774  1.000 28.572  0 424 ASP A N   1 ? 
ATOM   3145 C CA  . ASP A 1 420 ? 56.287 -57.793 -9.779  1.000 34.275  0 424 ASP A CA  1 ? 
ATOM   3146 C C   . ASP A 1 420 ? 55.735 -59.096 -9.216  1.000 30.272  0 424 ASP A C   1 ? 
ATOM   3147 O O   . ASP A 1 420 ? 55.042 -59.835 -9.925  1.000 32.883  0 424 ASP A O   1 ? 
ATOM   3148 C CB  . ASP A 1 420 ? 57.696 -58.038 -10.321 1.000 38.473  0 424 ASP A CB  1 ? 
ATOM   3149 C CG  . ASP A 1 420 ? 58.329 -56.799 -10.893 1.000 43.739  0 424 ASP A CG  1 ? 
ATOM   3150 O OD1 . ASP A 1 420 ? 57.623 -55.781 -11.052 1.000 51.806  0 424 ASP A OD1 1 ? 
ATOM   3151 O OD2 . ASP A 1 420 ? 59.547 -56.844 -11.176 1.000 44.992  0 424 ASP A OD2 1 ? 
ATOM   3152 N N   . TYR A 1 421 ? 56.023 -59.394 -7.939  1.000 27.624  0 425 TYR A N   1 ? 
ATOM   3153 C CA  . TYR A 1 421 ? 55.639 -60.693 -7.385  1.000 30.617  0 425 TYR A CA  1 ? 
ATOM   3154 C C   . TYR A 1 421 ? 54.131 -60.902 -7.438  1.000 33.343  0 425 TYR A C   1 ? 
ATOM   3155 O O   . TYR A 1 421 ? 53.666 -62.026 -7.662  1.000 32.185  0 425 TYR A O   1 ? 
ATOM   3156 C CB  . TYR A 1 421 ? 56.132 -60.838 -5.954  1.000 32.743  0 425 TYR A CB  1 ? 
ATOM   3157 C CG  . TYR A 1 421 ? 56.019 -62.247 -5.422  1.000 37.052  0 425 TYR A CG  1 ? 
ATOM   3158 C CD1 . TYR A 1 421 ? 57.057 -63.155 -5.602  1.000 37.576  0 425 TYR A CD1 1 ? 
ATOM   3159 C CD2 . TYR A 1 421 ? 54.880 -62.676 -4.737  1.000 32.659  0 425 TYR A CD2 1 ? 
ATOM   3160 C CE1 . TYR A 1 421 ? 56.981 -64.447 -5.116  1.000 36.810  0 425 TYR A CE1 1 ? 
ATOM   3161 C CE2 . TYR A 1 421 ? 54.783 -63.986 -4.253  1.000 34.996  0 425 TYR A CE2 1 ? 
ATOM   3162 C CZ  . TYR A 1 421 ? 55.849 -64.865 -4.443  1.000 42.610  0 425 TYR A CZ  1 ? 
ATOM   3163 O OH  . TYR A 1 421 ? 55.803 -66.163 -3.967  1.000 46.521  0 425 TYR A OH  1 ? 
ATOM   3164 N N   . ILE A 1 422 ? 53.352 -59.836 -7.238  1.000 35.631  0 426 ILE A N   1 ? 
ATOM   3165 C CA  . ILE A 1 422 ? 51.896 -59.924 -7.226  1.000 32.967  0 426 ILE A CA  1 ? 
ATOM   3166 C C   . ILE A 1 422 ? 51.269 -59.294 -8.450  1.000 31.362  0 426 ILE A C   1 ? 
ATOM   3167 O O   . ILE A 1 422 ? 50.037 -59.245 -8.544  1.000 36.331  0 426 ILE A O   1 ? 
ATOM   3168 C CB  . ILE A 1 422 ? 51.306 -59.312 -5.942  1.000 37.831  0 426 ILE A CB  1 ? 
ATOM   3169 C CG1 . ILE A 1 422 ? 51.541 -57.795 -5.892  1.000 32.822  0 426 ILE A CG1 1 ? 
ATOM   3170 C CG2 . ILE A 1 422 ? 51.863 -60.021 -4.710  1.000 25.495  0 426 ILE A CG2 1 ? 
ATOM   3171 C CD1 . ILE A 1 422 ? 51.127 -57.189 -4.563  1.000 33.520  0 426 ILE A CD1 1 ? 
ATOM   3172 N N   . GLY A 1 423 ? 52.074 -58.800 -9.385  1.000 34.780  0 427 GLY A N   1 ? 
ATOM   3173 C CA  . GLY A 1 423 ? 51.588 -58.413 -10.695 1.000 28.817  0 427 GLY A CA  1 ? 
ATOM   3174 C C   . GLY A 1 423 ? 50.963 -57.044 -10.795 1.000 31.122  0 427 GLY A C   1 ? 
ATOM   3175 O O   . GLY A 1 423 ? 50.076 -56.843 -11.627 1.000 39.878  0 427 GLY A O   1 ? 
ATOM   3176 N N   . VAL A 1 424 ? 51.417 -56.080 -9.991  1.000 32.141  0 428 VAL A N   1 ? 
ATOM   3177 C CA  . VAL A 1 424 ? 50.825 -54.749 -9.943  1.000 32.646  0 428 VAL A CA  1 ? 
ATOM   3178 C C   . VAL A 1 424 ? 51.908 -53.699 -10.156 1.000 32.164  0 428 VAL A C   1 ? 
ATOM   3179 O O   . VAL A 1 424 ? 53.093 -53.936 -9.930  1.000 44.290  0 428 VAL A O   1 ? 
ATOM   3180 C CB  . VAL A 1 424 ? 50.119 -54.485 -8.599  1.000 32.678  0 428 VAL A CB  1 ? 
ATOM   3181 C CG1 . VAL A 1 424 ? 49.242 -55.671 -8.203  1.000 27.690  0 428 VAL A CG1 1 ? 
ATOM   3182 C CG2 . VAL A 1 424 ? 51.168 -54.210 -7.522  1.000 27.714  0 428 VAL A CG2 1 ? 
ATOM   3183 N N   . ASP A 1 425 ? 51.483 -52.511 -10.555 1.000 29.877  0 429 ASP A N   1 ? 
ATOM   3184 C CA  . ASP A 1 425 ? 52.368 -51.359 -10.523 1.000 30.227  0 429 ASP A CA  1 ? 
ATOM   3185 C C   . ASP A 1 425 ? 52.488 -50.817 -9.097  1.000 38.355  0 429 ASP A C   1 ? 
ATOM   3186 O O   . ASP A 1 425 ? 51.521 -50.840 -8.320  1.000 28.922  0 429 ASP A O   1 ? 
ATOM   3187 C CB  . ASP A 1 425 ? 51.859 -50.270 -11.469 1.000 37.818  0 429 ASP A CB  1 ? 
ATOM   3188 C CG  . ASP A 1 425 ? 52.783 -49.087 -11.522 1.000 56.159  0 429 ASP A CG  1 ? 
ATOM   3189 O OD1 . ASP A 1 425 ? 52.766 -48.278 -10.565 1.000 58.723  0 429 ASP A OD1 1 ? 
ATOM   3190 O OD2 . ASP A 1 425 ? 53.543 -48.976 -12.511 1.000 67.140  0 429 ASP A OD2 1 ? 
ATOM   3191 N N   . LYS A 1 426 ? 53.686 -50.312 -8.761  1.000 29.580  0 430 LYS A N   1 ? 
ATOM   3192 C CA  . LYS A 1 426 ? 53.933 -49.806 -7.413  1.000 35.991  0 430 LYS A CA  1 ? 
ATOM   3193 C C   . LYS A 1 426 ? 52.870 -48.816 -6.974  1.000 36.797  0 430 LYS A C   1 ? 
ATOM   3194 O O   . LYS A 1 426 ? 52.492 -48.785 -5.799  1.000 38.136  0 430 LYS A O   1 ? 
ATOM   3195 C CB  . LYS A 1 426 ? 55.309 -49.152 -7.338  1.000 42.147  0 430 LYS A CB  1 ? 
ATOM   3196 C CG  . LYS A 1 426 ? 56.426 -50.164 -7.366  1.000 58.391  0 430 LYS A CG  1 ? 
ATOM   3197 C CD  . LYS A 1 426 ? 57.719 -49.619 -6.800  1.000 63.650  0 430 LYS A CD  1 ? 
ATOM   3198 C CE  . LYS A 1 426 ? 58.310 -48.587 -7.722  1.000 65.250  0 430 LYS A CE  1 ? 
ATOM   3199 N NZ  . LYS A 1 426 ? 59.785 -48.514 -7.562  1.000 70.711  0 430 LYS A NZ  1 ? 
ATOM   3200 N N   . ASN A 1 427 ? 52.359 -48.023 -7.906  1.000 41.555  0 431 ASN A N   1 ? 
ATOM   3201 C CA  . ASN A 1 427 ? 51.425 -46.950 -7.619  1.000 38.047  0 431 ASN A CA  1 ? 
ATOM   3202 C C   . ASN A 1 427 ? 49.981 -47.380 -7.791  1.000 38.794  0 431 ASN A C   1 ? 
ATOM   3203 O O   . ASN A 1 427 ? 49.084 -46.525 -7.809  1.000 38.565  0 431 ASN A O   1 ? 
ATOM   3204 C CB  . ASN A 1 427 ? 51.742 -45.754 -8.515  1.000 45.487  0 431 ASN A CB  1 ? 
ATOM   3205 C CG  . ASN A 1 427 ? 53.037 -45.073 -8.119  1.000 58.596  0 431 ASN A CG  1 ? 
ATOM   3206 O OD1 . ASN A 1 427 ? 53.315 -44.895 -6.935  1.000 70.122  0 431 ASN A OD1 1 ? 
ATOM   3207 N ND2 . ASN A 1 427 ? 53.849 -44.722 -9.101  1.000 65.134  0 431 ASN A ND2 1 ? 
ATOM   3208 N N   . GLY A 1 428 ? 49.733 -48.684 -7.888  1.000 33.520  0 432 GLY A N   1 ? 
ATOM   3209 C CA  . GLY A 1 428 ? 48.403 -49.182 -8.141  1.000 32.228  0 432 GLY A CA  1 ? 
ATOM   3210 C C   . GLY A 1 428 ? 48.047 -49.109 -9.616  1.000 36.994  0 432 GLY A C   1 ? 
ATOM   3211 O O   . GLY A 1 428 ? 48.820 -48.608 -10.440 1.000 40.560  0 432 GLY A O   1 ? 
ATOM   3212 N N   . PRO A 1 429 ? 46.855 -49.600 -9.984  1.000 39.165  0 433 PRO A N   1 ? 
ATOM   3213 C CA  . PRO A 1 429 ? 45.816 -50.212 -9.130  1.000 45.434  0 433 PRO A CA  1 ? 
ATOM   3214 C C   . PRO A 1 429 ? 46.302 -51.508 -8.502  1.000 41.871  0 433 PRO A C   1 ? 
ATOM   3215 O O   . PRO A 1 429 ? 47.141 -52.170 -9.105  1.000 39.407  0 433 PRO A O   1 ? 
ATOM   3216 C CB  . PRO A 1 429 ? 44.665 -50.489 -10.105 1.000 41.766  0 433 PRO A CB  1 ? 
ATOM   3217 C CG  . PRO A 1 429 ? 44.976 -49.668 -11.325 1.000 37.949  0 433 PRO A CG  1 ? 
ATOM   3218 C CD  . PRO A 1 429 ? 46.463 -49.575 -11.400 1.000 33.504  0 433 PRO A CD  1 ? 
ATOM   3219 N N   . TYR A 1 430 ? 45.798 -51.857 -7.320  1.000 39.678  0 434 TYR A N   1 ? 
ATOM   3220 C CA  . TYR A 1 430 ? 46.340 -52.976 -6.560  1.000 32.143  0 434 TYR A CA  1 ? 
ATOM   3221 C C   . TYR A 1 430 ? 45.497 -54.238 -6.633  1.000 35.228  0 434 TYR A C   1 ? 
ATOM   3222 O O   . TYR A 1 430 ? 45.968 -55.292 -6.199  1.000 42.868  0 434 TYR A O   1 ? 
ATOM   3223 C CB  . TYR A 1 430 ? 46.521 -52.571 -5.097  1.000 28.753  0 434 TYR A CB  1 ? 
ATOM   3224 C CG  . TYR A 1 430 ? 47.495 -51.428 -4.938  1.000 35.465  0 434 TYR A CG  1 ? 
ATOM   3225 C CD1 . TYR A 1 430 ? 48.851 -51.597 -5.228  1.000 34.412  0 434 TYR A CD1 1 ? 
ATOM   3226 C CD2 . TYR A 1 430 ? 47.069 -50.173 -4.514  1.000 35.457  0 434 TYR A CD2 1 ? 
ATOM   3227 C CE1 . TYR A 1 430 ? 49.750 -50.554 -5.089  1.000 31.422  0 434 TYR A CE1 1 ? 
ATOM   3228 C CE2 . TYR A 1 430 ? 47.968 -49.125 -4.364  1.000 31.649  0 434 TYR A CE2 1 ? 
ATOM   3229 C CZ  . TYR A 1 430 ? 49.309 -49.325 -4.660  1.000 31.564  0 434 TYR A CZ  1 ? 
ATOM   3230 O OH  . TYR A 1 430 ? 50.206 -48.287 -4.533  1.000 34.217  0 434 TYR A OH  1 ? 
ATOM   3231 N N   . LYS A 1 431 ? 44.286 -54.169 -7.182  1.000 27.398  0 435 LYS A N   1 ? 
ATOM   3232 C CA  . LYS A 1 431 ? 43.367 -55.297 -7.218  1.000 34.012  0 435 LYS A CA  1 ? 
ATOM   3233 C C   . LYS A 1 431 ? 42.766 -55.469 -8.606  1.000 31.933  0 435 LYS A C   1 ? 
ATOM   3234 O O   . LYS A 1 431 ? 42.640 -54.497 -9.357  1.000 32.346  0 435 LYS A O   1 ? 
ATOM   3235 C CB  . LYS A 1 431 ? 42.236 -55.107 -6.198  1.000 26.861  0 435 LYS A CB  1 ? 
ATOM   3236 C CG  . LYS A 1 431 ? 42.744 -54.896 -4.823  1.000 26.137  0 435 LYS A CG  1 ? 
ATOM   3237 C CD  . LYS A 1 431 ? 43.346 -56.182 -4.337  1.000 32.864  0 435 LYS A CD  1 ? 
ATOM   3238 C CE  . LYS A 1 431 ? 43.413 -56.206 -2.836  1.000 24.992  0 435 LYS A CE  1 ? 
ATOM   3239 N NZ  . LYS A 1 431 ? 44.358 -55.181 -2.324  1.000 24.840  0 435 LYS A NZ  1 ? 
ATOM   3240 N N   . PRO A 1 432 ? 42.371 -56.689 -8.971  1.000 36.610  0 436 PRO A N   1 ? 
ATOM   3241 C CA  . PRO A 1 432 ? 41.647 -56.866 -10.231 1.000 39.131  0 436 PRO A CA  1 ? 
ATOM   3242 C C   . PRO A 1 432 ? 40.309 -56.164 -10.146 1.000 45.703  0 436 PRO A C   1 ? 
ATOM   3243 O O   . PRO A 1 432 ? 39.843 -55.783 -9.071  1.000 40.226  0 436 PRO A O   1 ? 
ATOM   3244 C CB  . PRO A 1 432 ? 41.492 -58.382 -10.365 1.000 28.825  0 436 PRO A CB  1 ? 
ATOM   3245 C CG  . PRO A 1 432 ? 41.755 -58.926 -9.039  1.000 32.293  0 436 PRO A CG  1 ? 
ATOM   3246 C CD  . PRO A 1 432 ? 42.512 -57.951 -8.223  1.000 29.140  0 436 PRO A CD  1 ? 
ATOM   3247 N N   . ASP A 1 433 ? 39.702 -55.968 -11.312 1.000 64.774  0 437 ASP A N   1 ? 
ATOM   3248 C CA  . ASP A 1 433 ? 38.544 -55.083 -11.383 1.000 67.448  0 437 ASP A CA  1 ? 
ATOM   3249 C C   . ASP A 1 433 ? 37.423 -55.568 -10.477 1.000 50.359  0 437 ASP A C   1 ? 
ATOM   3250 O O   . ASP A 1 433 ? 36.760 -54.766 -9.814  1.000 44.242  0 437 ASP A O   1 ? 
ATOM   3251 C CB  . ASP A 1 433 ? 38.069 -54.969 -12.828 1.000 81.120  0 437 ASP A CB  1 ? 
ATOM   3252 C CG  . ASP A 1 433 ? 39.218 -54.763 -13.794 1.000 96.335  0 437 ASP A CG  1 ? 
ATOM   3253 O OD1 . ASP A 1 433 ? 40.267 -54.245 -13.357 1.000 100.320 0 437 ASP A OD1 1 ? 
ATOM   3254 O OD2 . ASP A 1 433 ? 39.084 -55.130 -14.982 1.000 102.773 0 437 ASP A OD2 1 ? 
ATOM   3255 N N   . HIS A 1 434 ? 37.226 -56.879 -10.395 1.000 45.503  0 438 HIS A N   1 ? 
ATOM   3256 C CA  . HIS A 1 434 ? 36.094 -57.425 -9.663  1.000 44.353  0 438 HIS A CA  1 ? 
ATOM   3257 C C   . HIS A 1 434 ? 36.465 -57.854 -8.248  1.000 45.555  0 438 HIS A C   1 ? 
ATOM   3258 O O   . HIS A 1 434 ? 35.768 -58.676 -7.643  1.000 44.982  0 438 HIS A O   1 ? 
ATOM   3259 C CB  . HIS A 1 434 ? 35.476 -58.573 -10.464 1.000 48.790  0 438 HIS A CB  1 ? 
ATOM   3260 C CG  . HIS A 1 434 ? 35.150 -58.190 -11.882 1.000 54.006  0 438 HIS A CG  1 ? 
ATOM   3261 N ND1 . HIS A 1 434 ? 34.664 -56.939 -12.221 1.000 51.359  0 438 HIS A ND1 1 ? 
ATOM   3262 C CD2 . HIS A 1 434 ? 35.277 -58.872 -13.047 1.000 44.000  0 438 HIS A CD2 1 ? 
ATOM   3263 C CE1 . HIS A 1 434 ? 34.504 -56.870 -13.530 1.000 41.939  0 438 HIS A CE1 1 ? 
ATOM   3264 N NE2 . HIS A 1 434 ? 34.865 -58.030 -14.053 1.000 50.430  0 438 HIS A NE2 1 ? 
ATOM   3265 N N   . TYR A 1 435 ? 37.536 -57.299 -7.701  1.000 36.207  0 439 TYR A N   1 ? 
ATOM   3266 C CA  . TYR A 1 435 ? 37.843 -57.541 -6.307  1.000 35.209  0 439 TYR A CA  1 ? 
ATOM   3267 C C   . TYR A 1 435 ? 36.739 -56.950 -5.435  1.000 42.216  0 439 TYR A C   1 ? 
ATOM   3268 O O   . TYR A 1 435 ? 36.256 -55.839 -5.684  1.000 39.563  0 439 TYR A O   1 ? 
ATOM   3269 C CB  . TYR A 1 435 ? 39.197 -56.929 -5.976  1.000 35.623  0 439 TYR A CB  1 ? 
ATOM   3270 C CG  . TYR A 1 435 ? 39.707 -57.315 -4.622  1.000 33.275  0 439 TYR A CG  1 ? 
ATOM   3271 C CD1 . TYR A 1 435 ? 40.210 -58.582 -4.391  1.000 25.782  0 439 TYR A CD1 1 ? 
ATOM   3272 C CD2 . TYR A 1 435 ? 39.681 -56.412 -3.572  1.000 30.580  0 439 TYR A CD2 1 ? 
ATOM   3273 C CE1 . TYR A 1 435 ? 40.655 -58.945 -3.161  1.000 25.135  0 439 TYR A CE1 1 ? 
ATOM   3274 C CE2 . TYR A 1 435 ? 40.144 -56.763 -2.336  1.000 30.180  0 439 TYR A CE2 1 ? 
ATOM   3275 C CZ  . TYR A 1 435 ? 40.625 -58.030 -2.135  1.000 29.669  0 439 TYR A CZ  1 ? 
ATOM   3276 O OH  . TYR A 1 435 ? 41.085 -58.381 -0.897  1.000 32.017  0 439 TYR A OH  1 ? 
ATOM   3277 N N   . ARG A 1 436 ? 36.319 -57.706 -4.419  1.000 33.143  0 440 ARG A N   1 ? 
ATOM   3278 C CA  . ARG A 1 436 ? 35.124 -57.351 -3.659  1.000 28.298  0 440 ARG A CA  1 ? 
ATOM   3279 C C   . ARG A 1 436 ? 35.432 -56.604 -2.382  1.000 30.309  0 440 ARG A C   1 ? 
ATOM   3280 O O   . ARG A 1 436 ? 34.512 -56.049 -1.771  1.000 34.307  0 440 ARG A O   1 ? 
ATOM   3281 C CB  . ARG A 1 436 ? 34.322 -58.599 -3.315  1.000 28.840  0 440 ARG A CB  1 ? 
ATOM   3282 C CG  . ARG A 1 436 ? 33.922 -59.397 -4.531  1.000 28.498  0 440 ARG A CG  1 ? 
ATOM   3283 C CD  . ARG A 1 436 ? 32.619 -60.132 -4.301  1.000 27.256  0 440 ARG A CD  1 ? 
ATOM   3284 N NE  . ARG A 1 436 ? 31.968 -60.475 -5.553  1.000 35.702  0 440 ARG A NE  1 ? 
ATOM   3285 C CZ  . ARG A 1 436 ? 32.261 -61.538 -6.285  1.000 28.269  0 440 ARG A CZ  1 ? 
ATOM   3286 N NH1 . ARG A 1 436 ? 33.208 -62.382 -5.894  1.000 32.170  0 440 ARG A NH1 1 ? 
ATOM   3287 N NH2 . ARG A 1 436 ? 31.595 -61.759 -7.407  1.000 40.929  0 440 ARG A NH2 1 ? 
ATOM   3288 N N   . TYR A 1 437 ? 36.699 -56.578 -1.982  1.000 29.317  0 441 TYR A N   1 ? 
ATOM   3289 C CA  . TYR A 1 437 ? 37.138 -55.968 -0.733  1.000 33.967  0 441 TYR A CA  1 ? 
ATOM   3290 C C   . TYR A 1 437 ? 36.353 -56.506 0.464   1.000 38.134  0 441 TYR A C   1 ? 
ATOM   3291 O O   . TYR A 1 437 ? 35.823 -57.636 0.441   1.000 32.133  0 441 TYR A O   1 ? 
ATOM   3292 C CB  . TYR A 1 437 ? 37.039 -54.440 -0.810  1.000 26.906  0 441 TYR A CB  1 ? 
ATOM   3293 C CG  . TYR A 1 437 ? 37.861 -53.852 -1.925  1.000 28.338  0 441 TYR A CG  1 ? 
ATOM   3294 C CD1 . TYR A 1 437 ? 37.340 -53.772 -3.207  1.000 35.096  0 441 TYR A CD1 1 ? 
ATOM   3295 C CD2 . TYR A 1 437 ? 39.170 -53.404 -1.713  1.000 28.027  0 441 TYR A CD2 1 ? 
ATOM   3296 C CE1 . TYR A 1 437 ? 38.062 -53.262 -4.240  1.000 33.596  0 441 TYR A CE1 1 ? 
ATOM   3297 C CE2 . TYR A 1 437 ? 39.921 -52.882 -2.765  1.000 25.685  0 441 TYR A CE2 1 ? 
ATOM   3298 C CZ  . TYR A 1 437 ? 39.344 -52.815 -4.030  1.000 33.091  0 441 TYR A CZ  1 ? 
ATOM   3299 O OH  . TYR A 1 437 ? 40.006 -52.305 -5.125  1.000 28.419  0 441 TYR A OH  1 ? 
ATOM   3300 O OXT . TYR A 1 437 ? 36.269 -55.802 1.475   1.000 34.607  0 441 TYR A OXT 1 ? 
HETATM 3301 P PA  . NAD B 2 .   ? 21.813 -53.368 -0.855  1.000 36.230  0 501 NAD A PA  1 ? 
HETATM 3302 O O1A . NAD B 2 .   ? 21.240 -53.815 -2.152  1.000 37.230  0 501 NAD A O1A 1 ? 
HETATM 3303 O O2A . NAD B 2 .   ? 23.249 -53.654 -0.580  1.000 30.720  0 501 NAD A O2A 1 ? 
HETATM 3304 O O5B . NAD B 2 .   ? 20.978 -54.017 0.331   1.000 32.500  0 501 NAD A O5B 1 ? 
HETATM 3305 C C5B . NAD B 2 .   ? 19.591 -54.276 0.269   1.000 32.440  0 501 NAD A C5B 1 ? 
HETATM 3306 C C4B . NAD B 2 .   ? 19.396 -55.640 0.894   1.000 29.720  0 501 NAD A C4B 1 ? 
HETATM 3307 O O4B . NAD B 2 .   ? 18.046 -55.823 1.292   1.000 29.730  0 501 NAD A O4B 1 ? 
HETATM 3308 C C3B . NAD B 2 .   ? 19.706 -56.728 -0.106  1.000 43.740  0 501 NAD A C3B 1 ? 
HETATM 3309 O O3B . NAD B 2 .   ? 20.630 -57.634 0.470   1.000 45.710  0 501 NAD A O3B 1 ? 
HETATM 3310 C C2B . NAD B 2 .   ? 18.387 -57.404 -0.372  1.000 43.870  0 501 NAD A C2B 1 ? 
HETATM 3311 O O2B . NAD B 2 .   ? 18.515 -58.800 -0.594  1.000 39.800  0 501 NAD A O2B 1 ? 
HETATM 3312 C C1B . NAD B 2 .   ? 17.650 -57.131 0.908   1.000 41.640  0 501 NAD A C1B 1 ? 
HETATM 3313 N N9A . NAD B 2 .   ? 16.208 -57.206 0.664   1.000 37.470  0 501 NAD A N9A 1 ? 
HETATM 3314 C C8A . NAD B 2 .   ? 15.557 -56.728 -0.394  1.000 35.970  0 501 NAD A C8A 1 ? 
HETATM 3315 N N7A . NAD B 2 .   ? 14.244 -56.971 -0.291  1.000 35.780  0 501 NAD A N7A 1 ? 
HETATM 3316 C C5A . NAD B 2 .   ? 14.051 -57.625 0.848   1.000 35.860  0 501 NAD A C5A 1 ? 
HETATM 3317 C C6A . NAD B 2 .   ? 12.899 -58.178 1.562   1.000 33.580  0 501 NAD A C6A 1 ? 
HETATM 3318 N N6A . NAD B 2 .   ? 11.660 -58.079 1.048   1.000 30.110  0 501 NAD A N6A 1 ? 
HETATM 3319 N N1A . NAD B 2 .   ? 13.134 -58.786 2.734   1.000 34.300  0 501 NAD A N1A 1 ? 
HETATM 3320 C C2A . NAD B 2 .   ? 14.365 -58.887 3.248   1.000 32.650  0 501 NAD A C2A 1 ? 
HETATM 3321 N N3A . NAD B 2 .   ? 15.456 -58.407 2.658   1.000 32.690  0 501 NAD A N3A 1 ? 
HETATM 3322 C C4A . NAD B 2 .   ? 15.353 -57.780 1.478   1.000 35.870  0 501 NAD A C4A 1 ? 
HETATM 3323 O O3  . NAD B 2 .   ? 21.510 -51.809 -0.725  1.000 24.360  0 501 NAD A O3  1 ? 
HETATM 3324 P PN  . NAD B 2 .   ? 22.032 -50.908 0.471   1.000 26.930  0 501 NAD A PN  1 ? 
HETATM 3325 O O1N . NAD B 2 .   ? 23.187 -50.142 -0.048  1.000 34.860  0 501 NAD A O1N 1 ? 
HETATM 3326 O O2N . NAD B 2 .   ? 22.169 -51.717 1.706   1.000 30.000  0 501 NAD A O2N 1 ? 
HETATM 3327 O O5D . NAD B 2 .   ? 20.885 -49.841 0.693   1.000 33.150  0 501 NAD A O5D 1 ? 
HETATM 3328 C C5D . NAD B 2 .   ? 19.543 -50.225 0.942   1.000 26.700  0 501 NAD A C5D 1 ? 
HETATM 3329 C C4D . NAD B 2 .   ? 18.681 -48.986 0.859   1.000 30.050  0 501 NAD A C4D 1 ? 
HETATM 3330 O O4D . NAD B 2 .   ? 19.203 -47.994 1.725   1.000 32.950  0 501 NAD A O4D 1 ? 
HETATM 3331 C C3D . NAD B 2 .   ? 18.710 -48.393 -0.525  1.000 34.850  0 501 NAD A C3D 1 ? 
HETATM 3332 O O3D . NAD B 2 .   ? 17.402 -47.954 -0.858  1.000 41.380  0 501 NAD A O3D 1 ? 
HETATM 3333 C C2D . NAD B 2 .   ? 19.649 -47.226 -0.428  1.000 41.030  0 501 NAD A C2D 1 ? 
HETATM 3334 O O2D . NAD B 2 .   ? 19.300 -46.220 -1.366  1.000 36.800  0 501 NAD A O2D 1 ? 
HETATM 3335 C C1D . NAD B 2 .   ? 19.452 -46.798 1.009   1.000 40.730  0 501 NAD A C1D 1 ? 
HETATM 3336 N N1N . NAD B 2 .   ? 20.634 -46.184 1.574   1.000 39.700  0 501 NAD A N1N 1 ? 
HETATM 3337 C C2N . NAD B 2 .   ? 20.481 -45.457 2.668   1.000 35.970  0 501 NAD A C2N 1 ? 
HETATM 3338 C C3N . NAD B 2 .   ? 21.557 -44.836 3.268   1.000 41.700  0 501 NAD A C3N 1 ? 
HETATM 3339 C C7N . NAD B 2 .   ? 21.325 -44.019 4.490   1.000 42.750  0 501 NAD A C7N 1 ? 
HETATM 3340 O O7N . NAD B 2 .   ? 22.107 -43.147 4.788   1.000 43.670  0 501 NAD A O7N 1 ? 
HETATM 3341 N N7N . NAD B 2 .   ? 20.251 -44.269 5.218   1.000 39.660  0 501 NAD A N7N 1 ? 
HETATM 3342 C C4N . NAD B 2 .   ? 22.818 -44.984 2.728   1.000 46.810  0 501 NAD A C4N 1 ? 
HETATM 3343 C C5N . NAD B 2 .   ? 22.950 -45.754 1.587   1.000 50.040  0 501 NAD A C5N 1 ? 
HETATM 3344 C C6N . NAD B 2 .   ? 21.832 -46.352 1.023   1.000 45.200  0 501 NAD A C6N 1 ? 
HETATM 3345 S S   . SO4 C 3 .   ? 20.372 -42.353 0.913   1.000 48.000  0 502 SO4 A S   1 ? 
HETATM 3346 O O1  . SO4 C 3 .   ? 21.491 -43.144 0.411   1.000 52.830  0 502 SO4 A O1  1 ? 
HETATM 3347 O O2  . SO4 C 3 .   ? 20.066 -41.271 -0.020  1.000 51.730  0 502 SO4 A O2  1 ? 
HETATM 3348 O O3  . SO4 C 3 .   ? 19.209 -43.230 1.039   1.000 53.510  0 502 SO4 A O3  1 ? 
HETATM 3349 O O4  . SO4 C 3 .   ? 20.726 -41.780 2.200   1.000 40.430  0 502 SO4 A O4  1 ? 
HETATM 3350 O O   . HOH D 4 .   ? 35.723 -60.894 -7.646  1.000 39.060  0 601 HOH A O   1 ? 
HETATM 3351 O O   . HOH D 4 .   ? 46.799 -36.194 -7.463  1.000 49.950  0 602 HOH A O   1 ? 
HETATM 3352 O O   . HOH D 4 .   ? 2.415  -33.321 2.630   1.000 49.980  0 603 HOH A O   1 ? 
HETATM 3353 O O   . HOH D 4 .   ? 18.143 -45.356 -25.183 1.000 55.330  0 604 HOH A O   1 ? 
HETATM 3354 O O   . HOH D 4 .   ? 34.577 -46.741 -9.241  1.000 43.430  0 605 HOH A O   1 ? 
HETATM 3355 O O   . HOH D 4 .   ? 32.303 -43.188 1.562   1.000 46.350  0 606 HOH A O   1 ? 
HETATM 3356 O O   . HOH D 4 .   ? 13.692 -57.439 24.377  1.000 28.700  0 607 HOH A O   1 ? 
HETATM 3357 O O   . HOH D 4 .   ? 27.163 -18.553 15.827  1.000 56.280  0 608 HOH A O   1 ? 
HETATM 3358 O O   . HOH D 4 .   ? 16.081 -37.252 22.301  1.000 41.980  0 609 HOH A O   1 ? 
HETATM 3359 O O   . HOH D 4 .   ? 26.536 -21.750 -8.238  1.000 52.650  0 610 HOH A O   1 ? 
HETATM 3360 O O   . HOH D 4 .   ? 20.249 -63.025 16.709  1.000 23.980  0 611 HOH A O   1 ? 
HETATM 3361 O O   . HOH D 4 .   ? 16.333 -51.850 -11.544 1.000 56.540  0 612 HOH A O   1 ? 
HETATM 3362 O O   . HOH D 4 .   ? 36.895 -53.872 -7.119  1.000 38.720  0 613 HOH A O   1 ? 
HETATM 3363 O O   . HOH D 4 .   ? 16.382 -52.450 27.193  1.000 42.330  0 614 HOH A O   1 ? 
HETATM 3364 O O   . HOH D 4 .   ? 12.334 -26.160 9.036   1.000 40.270  0 615 HOH A O   1 ? 
HETATM 3365 O O   . HOH D 4 .   ? 37.307 -59.990 -3.911  1.000 36.750  0 616 HOH A O   1 ? 
HETATM 3366 O O   . HOH D 4 .   ? 33.457 -25.795 2.610   1.000 43.820  0 617 HOH A O   1 ? 
HETATM 3367 O O   . HOH D 4 .   ? 23.313 -62.428 -4.491  1.000 29.720  0 618 HOH A O   1 ? 
HETATM 3368 O O   . HOH D 4 .   ? 6.202  -63.952 16.980  1.000 35.510  0 619 HOH A O   1 ? 
HETATM 3369 O O   . HOH D 4 .   ? 14.411 -17.631 3.631   1.000 48.750  0 620 HOH A O   1 ? 
HETATM 3370 O O   . HOH D 4 .   ? 17.567 -70.358 14.885  1.000 51.770  0 621 HOH A O   1 ? 
HETATM 3371 O O   . HOH D 4 .   ? 18.981 -46.245 -22.363 1.000 56.460  0 622 HOH A O   1 ? 
HETATM 3372 O O   . HOH D 4 .   ? 15.371 -50.271 -4.679  1.000 43.340  0 623 HOH A O   1 ? 
HETATM 3373 O O   . HOH D 4 .   ? 6.784  -40.471 12.512  1.000 36.620  0 624 HOH A O   1 ? 
HETATM 3374 O O   . HOH D 4 .   ? 40.580 -31.739 5.891   1.000 31.370  0 625 HOH A O   1 ? 
HETATM 3375 O O   . HOH D 4 .   ? 25.150 -51.239 -1.340  1.000 46.910  0 626 HOH A O   1 ? 
HETATM 3376 O O   . HOH D 4 .   ? 30.812 -22.386 -14.423 1.000 52.350  0 627 HOH A O   1 ? 
HETATM 3377 O O   . HOH D 4 .   ? 15.088 -39.295 -3.503  1.000 41.890  0 628 HOH A O   1 ? 
HETATM 3378 O O   . HOH D 4 .   ? 6.884  -56.530 18.445  1.000 35.670  0 629 HOH A O   1 ? 
HETATM 3379 O O   . HOH D 4 .   ? 32.281 -21.314 -9.365  1.000 47.970  0 630 HOH A O   1 ? 
HETATM 3380 O O   . HOH D 4 .   ? 59.416 -60.364 -7.953  1.000 31.820  0 631 HOH A O   1 ? 
HETATM 3381 O O   . HOH D 4 .   ? 46.849 -55.991 -3.836  1.000 25.270  0 632 HOH A O   1 ? 
HETATM 3382 O O   . HOH D 4 .   ? 31.410 -46.375 12.062  1.000 25.930  0 633 HOH A O   1 ? 
HETATM 3383 O O   . HOH D 4 .   ? 46.582 -45.611 -6.643  1.000 43.690  0 634 HOH A O   1 ? 
HETATM 3384 O O   . HOH D 4 .   ? 38.458 -32.680 13.153  1.000 21.250  0 635 HOH A O   1 ? 
HETATM 3385 O O   . HOH D 4 .   ? 54.882 -52.882 6.360   1.000 23.340  0 636 HOH A O   1 ? 
HETATM 3386 O O   . HOH D 4 .   ? 10.021 -48.690 22.954  1.000 26.590  0 637 HOH A O   1 ? 
HETATM 3387 O O   . HOH D 4 .   ? 22.800 -40.792 3.800   1.000 33.890  0 638 HOH A O   1 ? 
HETATM 3388 O O   . HOH D 4 .   ? 11.743 -44.122 9.868   1.000 36.950  0 639 HOH A O   1 ? 
HETATM 3389 O O   . HOH D 4 .   ? -3.636 -61.154 12.217  1.000 40.700  0 640 HOH A O   1 ? 
HETATM 3390 O O   . HOH D 4 .   ? 12.619 -44.666 24.907  1.000 35.890  0 641 HOH A O   1 ? 
HETATM 3391 O O   . HOH D 4 .   ? 43.950 -37.388 5.200   1.000 28.510  0 642 HOH A O   1 ? 
HETATM 3392 O O   . HOH D 4 .   ? 37.527 -49.379 -7.721  1.000 36.380  0 643 HOH A O   1 ? 
HETATM 3393 O O   . HOH D 4 .   ? 48.789 -52.266 -11.209 1.000 43.380  0 644 HOH A O   1 ? 
HETATM 3394 O O   . HOH D 4 .   ? 33.329 -36.436 10.739  1.000 27.050  0 645 HOH A O   1 ? 
HETATM 3395 O O   . HOH D 4 .   ? 23.142 -40.084 19.314  0.500 21.080  0 646 HOH A O   1 ? 
HETATM 3396 O O   . HOH D 4 .   ? 61.277 -56.491 -1.196  1.000 35.350  0 647 HOH A O   1 ? 
HETATM 3397 O O   . HOH D 4 .   ? 12.665 -41.836 2.908   1.000 38.100  0 648 HOH A O   1 ? 
HETATM 3398 O O   . HOH D 4 .   ? 13.868 -30.897 -2.944  1.000 34.410  0 649 HOH A O   1 ? 
HETATM 3399 O O   . HOH D 4 .   ? 30.753 -29.819 11.591  1.000 35.240  0 650 HOH A O   1 ? 
HETATM 3400 O O   . HOH D 4 .   ? 34.525 -51.699 4.446   1.000 31.600  0 651 HOH A O   1 ? 
HETATM 3401 O O   . HOH D 4 .   ? -7.834 -52.135 10.013  1.000 49.600  0 652 HOH A O   1 ? 
HETATM 3402 O O   . HOH D 4 .   ? 42.071 -52.927 -11.804 1.000 34.160  0 653 HOH A O   1 ? 
HETATM 3403 O O   . HOH D 4 .   ? 16.780 -22.515 6.623   1.000 64.630  0 654 HOH A O   1 ? 
HETATM 3404 O O   . HOH D 4 .   ? 14.408 -65.507 -1.378  1.000 20.870  0 655 HOH A O   1 ? 
HETATM 3405 O O   . HOH D 4 .   ? 1.543  -61.300 9.259   1.000 39.470  0 656 HOH A O   1 ? 
HETATM 3406 O O   . HOH D 4 .   ? 45.783 -38.666 3.408   1.000 32.220  0 657 HOH A O   1 ? 
HETATM 3407 O O   . HOH D 4 .   ? 13.560 -47.603 0.064   1.000 38.350  0 658 HOH A O   1 ? 
HETATM 3408 O O   . HOH D 4 .   ? 1.884  -59.654 6.376   1.000 38.470  0 659 HOH A O   1 ? 
HETATM 3409 O O   . HOH D 4 .   ? 31.788 -32.253 11.336  1.000 27.590  0 660 HOH A O   1 ? 
HETATM 3410 O O   . HOH D 4 .   ? -3.413 -45.925 23.676  1.000 39.150  0 661 HOH A O   1 ? 
HETATM 3411 O O   . HOH D 4 .   ? 30.052 -56.292 8.839   1.000 39.780  0 662 HOH A O   1 ? 
HETATM 3412 O O   . HOH D 4 .   ? 14.825 -63.659 6.332   1.000 29.410  0 663 HOH A O   1 ? 
HETATM 3413 O O   . HOH D 4 .   ? 39.357 -57.920 1.215   1.000 31.690  0 664 HOH A O   1 ? 
HETATM 3414 O O   . HOH D 4 .   ? 24.217 -42.647 0.343   1.000 38.910  0 665 HOH A O   1 ? 
HETATM 3415 O O   . HOH D 4 .   ? 5.636  -36.721 -3.283  1.000 58.990  0 666 HOH A O   1 ? 
HETATM 3416 O O   . HOH D 4 .   ? 64.791 -57.123 -5.978  1.000 31.960  0 667 HOH A O   1 ? 
HETATM 3417 O O   . HOH D 4 .   ? 28.803 -54.311 -1.124  1.000 35.140  0 668 HOH A O   1 ? 
HETATM 3418 O O   . HOH D 4 .   ? 3.797  -60.577 4.971   1.000 36.720  0 669 HOH A O   1 ? 
HETATM 3419 O O   . HOH D 4 .   ? 2.728  -55.313 23.921  1.000 44.950  0 670 HOH A O   1 ? 
HETATM 3420 O O   . HOH D 4 .   ? 53.200 -49.498 -3.170  1.000 26.870  0 671 HOH A O   1 ? 
HETATM 3421 O O   . HOH D 4 .   ? 19.161 -55.417 -3.178  1.000 35.450  0 672 HOH A O   1 ? 
HETATM 3422 O O   . HOH D 4 .   ? 16.938 -12.916 -14.775 1.000 55.730  0 673 HOH A O   1 ? 
HETATM 3423 O O   . HOH D 4 .   ? 11.161 -60.982 22.410  1.000 41.590  0 674 HOH A O   1 ? 
HETATM 3424 O O   . HOH D 4 .   ? 7.846  -66.798 7.180   1.000 38.820  0 675 HOH A O   1 ? 
HETATM 3425 O O   . HOH D 4 .   ? 42.204 -47.996 -12.448 1.000 29.480  0 676 HOH A O   1 ? 
HETATM 3426 O O   . HOH D 4 .   ? -4.056 -57.304 9.381   1.000 39.220  0 677 HOH A O   1 ? 
HETATM 3427 O O   . HOH D 4 .   ? 11.735 -43.012 -12.247 1.000 47.800  0 678 HOH A O   1 ? 
HETATM 3428 O O   . HOH D 4 .   ? 57.219 -49.332 3.219   1.000 28.850  0 679 HOH A O   1 ? 
HETATM 3429 O O   . HOH D 4 .   ? 3.995  -57.020 1.462   1.000 27.720  0 680 HOH A O   1 ? 
HETATM 3430 O O   . HOH D 4 .   ? 34.237 -22.258 6.295   1.000 46.320  0 681 HOH A O   1 ? 
HETATM 3431 O O   . HOH D 4 .   ? 11.920 -66.820 11.179  1.000 42.840  0 682 HOH A O   1 ? 
HETATM 3432 O O   . HOH D 4 .   ? 26.323 -36.019 11.173  1.000 45.000  0 683 HOH A O   1 ? 
HETATM 3433 O O   . HOH D 4 .   ? -0.644 -61.478 17.396  1.000 32.830  0 684 HOH A O   1 ? 
HETATM 3434 O O   . HOH D 4 .   ? 16.544 -38.003 -5.688  1.000 40.770  0 685 HOH A O   1 ? 
HETATM 3435 O O   . HOH D 4 .   ? 23.639 -17.986 13.073  1.000 47.750  0 686 HOH A O   1 ? 
HETATM 3436 O O   . HOH D 4 .   ? 34.031 -22.668 13.617  1.000 37.020  0 687 HOH A O   1 ? 
HETATM 3437 O O   . HOH D 4 .   ? 36.002 -49.620 -10.583 1.000 42.680  0 688 HOH A O   1 ? 
HETATM 3438 O O   . HOH D 4 .   ? 9.180  -58.948 2.349   1.000 31.050  0 689 HOH A O   1 ? 
HETATM 3439 O O   . HOH D 4 .   ? 27.086 -26.095 -22.212 1.000 41.910  0 690 HOH A O   1 ? 
HETATM 3440 O O   . HOH D 4 .   ? 21.080 -50.912 -7.338  1.000 37.460  0 691 HOH A O   1 ? 
HETATM 3441 O O   . HOH D 4 .   ? 26.115 -42.977 17.342  1.000 36.070  0 692 HOH A O   1 ? 
HETATM 3442 O O   . HOH D 4 .   ? 13.025 -36.710 15.280  1.000 48.620  0 693 HOH A O   1 ? 
HETATM 3443 O O   . HOH D 4 .   ? 55.920 -50.659 -10.685 1.000 40.240  0 694 HOH A O   1 ? 
HETATM 3444 O O   . HOH D 4 .   ? 8.244  -61.853 6.377   1.000 31.470  0 695 HOH A O   1 ? 
HETATM 3445 O O   . HOH D 4 .   ? 38.441 -59.320 -11.612 1.000 43.910  0 696 HOH A O   1 ? 
HETATM 3446 O O   . HOH D 4 .   ? 10.614 -51.074 22.196  1.000 44.760  0 697 HOH A O   1 ? 
HETATM 3447 O O   . HOH D 4 .   ? 24.447 -39.107 5.077   1.000 41.450  0 698 HOH A O   1 ? 
HETATM 3448 O O   . HOH D 4 .   ? 5.211  -35.578 12.416  1.000 45.260  0 699 HOH A O   1 ? 
HETATM 3449 O O   . HOH D 4 .   ? 10.951 -41.304 1.335   1.000 31.710  0 700 HOH A O   1 ? 
HETATM 3450 O O   . HOH D 4 .   ? 2.311  -43.511 25.299  1.000 41.010  0 701 HOH A O   1 ? 
HETATM 3451 O O   . HOH D 4 .   ? 49.412 -41.750 4.953   1.000 46.710  0 702 HOH A O   1 ? 
HETATM 3452 O O   . HOH D 4 .   ? 11.440 -58.535 5.256   1.000 30.370  0 703 HOH A O   1 ? 
HETATM 3453 O O   . HOH D 4 .   ? 13.387 -65.375 16.880  1.000 47.960  0 704 HOH A O   1 ? 
HETATM 3454 O O   . HOH D 4 .   ? 47.553 -38.280 -7.655  1.000 38.800  0 705 HOH A O   1 ? 
HETATM 3455 O O   . HOH D 4 .   ? 45.858 -43.537 -6.708  1.000 38.740  0 706 HOH A O   1 ? 
HETATM 3456 O O   . HOH D 4 .   ? 15.770 -15.509 -17.987 1.000 67.850  0 707 HOH A O   1 ? 
HETATM 3457 O O   . HOH D 4 .   ? 20.514 -68.100 11.268  1.000 33.970  0 708 HOH A O   1 ? 
HETATM 3458 O O   . HOH D 4 .   ? 47.118 -40.601 -4.481  1.000 43.560  0 709 HOH A O   1 ? 
HETATM 3459 O O   . HOH D 4 .   ? 5.696  -33.208 13.643  1.000 44.090  0 710 HOH A O   1 ? 
HETATM 3460 O O   . HOH D 4 .   ? 56.500 -46.968 4.035   1.000 57.010  0 711 HOH A O   1 ? 
HETATM 3461 O O   . HOH D 4 .   ? 20.224 -73.511 14.414  1.000 29.780  0 712 HOH A O   1 ? 
HETATM 3462 O O   . HOH D 4 .   ? 49.800 -41.905 13.471  1.000 56.710  0 713 HOH A O   1 ? 
HETATM 3463 O O   . HOH D 4 .   ? 15.346 -14.025 -16.294 1.000 52.840  0 714 HOH A O   1 ? 
HETATM 3464 O O   . HOH D 4 .   ? -5.577 -44.245 23.239  1.000 45.740  0 715 HOH A O   1 ? 
HETATM 3465 O O   . HOH D 4 .   ? 1.545  -37.658 9.540   1.000 58.810  0 716 HOH A O   1 ? 
HETATM 3466 O O   . HOH D 4 .   ? 24.467 -42.378 19.314  0.500 46.430  0 717 HOH A O   1 ? 
HETATM 3467 O O   . HOH D 4 .   ? -3.036 -61.500 14.649  1.000 51.570  0 718 HOH A O   1 ? 
HETATM 3468 O O   . HOH D 4 .   ? 0.250  -60.205 19.768  1.000 50.710  0 719 HOH A O   1 ? 
HETATM 3469 O O   . HOH D 4 .   ? -0.140 -39.082 9.430   1.000 58.690  0 720 HOH A O   1 ? 
HETATM 3470 O O   . HOH D 4 .   ? 15.676 -68.564 15.416  1.000 37.080  0 721 HOH A O   1 ? 
HETATM 3471 O O   . HOH D 4 .   ? 15.826 -66.475 17.121  1.000 40.700  0 722 HOH A O   1 ? 
# 
