data_8WXJ
# 
_entry.id   8WXJ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8WXJ         pdb_00008wxj 10.2210/pdb8wxj/pdb 
WWPDB D_1300042203 ?            ?                   
EMDB  EMD-37909    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-06 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8WXJ 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-29 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'human CLC-1 D136G closed state' 
_pdbx_database_related.db_id          EMD-37909 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhangmingfeng@westlake.edu.cn 
_pdbx_contact_author.name_first         Mingfeng 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0138-3934 
# 
_audit_author.name               'Zhang, M.F.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0002-0138-3934 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'CLC-1 in SCN environment' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
_citation_author.citation_id        primary 
_citation_author.name               'Zhang, M.F.' 
_citation_author.ordinal            1 
_citation_author.identifier_ORCID   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Chloride channel protein 1' 108675.133 2 ? D136G ? ? 
2 non-polymer syn 'THIOCYANATE ION'            58.082     6 ? ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQIYGHHKEQFSDREQDIGMPK
KTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIFLVLLGLLMALVSWSMGYVSAKSLQAYKWSYAQMQPSLPLQ
FLVWVTFPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIAS
ICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLA
VWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFV
IASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIP
CGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMM
VAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLV
DSKDSMILLGSVERSELQALLQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLS
GKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRARPTKKKTTQDSTDLVDNMSPE
EIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQL
RPPLASFRNTTSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESP
GLEEELADILQGPSLRSTDEEDEDELIL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQIYGHHKEQFSDREQDIGMPK
KTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIFLVLLGLLMALVSWSMGYVSAKSLQAYKWSYAQMQPSLPLQ
FLVWVTFPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIAS
ICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLA
VWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFV
IASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIP
CGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMM
VAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLV
DSKDSMILLGSVERSELQALLQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLS
GKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRARPTKKKTTQDSTDLVDNMSPE
EIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQL
RPPLASFRNTTSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESP
GLEEELADILQGPSLRSTDEEDEDELIL
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'THIOCYANATE ION' 
_pdbx_entity_nonpoly.comp_id     SCN 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLU n 
1 3   GLN n 
1 4   SER n 
1 5   ARG n 
1 6   SER n 
1 7   GLN n 
1 8   GLN n 
1 9   ARG n 
1 10  GLY n 
1 11  GLY n 
1 12  GLU n 
1 13  GLN n 
1 14  SER n 
1 15  TRP n 
1 16  TRP n 
1 17  GLY n 
1 18  SER n 
1 19  ASP n 
1 20  PRO n 
1 21  GLN n 
1 22  TYR n 
1 23  GLN n 
1 24  TYR n 
1 25  MET n 
1 26  PRO n 
1 27  PHE n 
1 28  GLU n 
1 29  HIS n 
1 30  CYS n 
1 31  THR n 
1 32  SER n 
1 33  TYR n 
1 34  GLY n 
1 35  LEU n 
1 36  PRO n 
1 37  SER n 
1 38  GLU n 
1 39  ASN n 
1 40  GLY n 
1 41  GLY n 
1 42  LEU n 
1 43  GLN n 
1 44  HIS n 
1 45  ARG n 
1 46  LEU n 
1 47  ARG n 
1 48  LYS n 
1 49  ASP n 
1 50  ALA n 
1 51  GLY n 
1 52  PRO n 
1 53  ARG n 
1 54  HIS n 
1 55  ASN n 
1 56  VAL n 
1 57  HIS n 
1 58  PRO n 
1 59  THR n 
1 60  GLN n 
1 61  ILE n 
1 62  TYR n 
1 63  GLY n 
1 64  HIS n 
1 65  HIS n 
1 66  LYS n 
1 67  GLU n 
1 68  GLN n 
1 69  PHE n 
1 70  SER n 
1 71  ASP n 
1 72  ARG n 
1 73  GLU n 
1 74  GLN n 
1 75  ASP n 
1 76  ILE n 
1 77  GLY n 
1 78  MET n 
1 79  PRO n 
1 80  LYS n 
1 81  LYS n 
1 82  THR n 
1 83  GLY n 
1 84  SER n 
1 85  SER n 
1 86  SER n 
1 87  THR n 
1 88  VAL n 
1 89  ASP n 
1 90  SER n 
1 91  LYS n 
1 92  ASP n 
1 93  GLU n 
1 94  ASP n 
1 95  HIS n 
1 96  TYR n 
1 97  SER n 
1 98  LYS n 
1 99  CYS n 
1 100 GLN n 
1 101 ASP n 
1 102 CYS n 
1 103 ILE n 
1 104 HIS n 
1 105 ARG n 
1 106 LEU n 
1 107 GLY n 
1 108 GLN n 
1 109 VAL n 
1 110 VAL n 
1 111 ARG n 
1 112 ARG n 
1 113 LYS n 
1 114 LEU n 
1 115 GLY n 
1 116 GLU n 
1 117 ASP n 
1 118 GLY n 
1 119 ILE n 
1 120 PHE n 
1 121 LEU n 
1 122 VAL n 
1 123 LEU n 
1 124 LEU n 
1 125 GLY n 
1 126 LEU n 
1 127 LEU n 
1 128 MET n 
1 129 ALA n 
1 130 LEU n 
1 131 VAL n 
1 132 SER n 
1 133 TRP n 
1 134 SER n 
1 135 MET n 
1 136 GLY n 
1 137 TYR n 
1 138 VAL n 
1 139 SER n 
1 140 ALA n 
1 141 LYS n 
1 142 SER n 
1 143 LEU n 
1 144 GLN n 
1 145 ALA n 
1 146 TYR n 
1 147 LYS n 
1 148 TRP n 
1 149 SER n 
1 150 TYR n 
1 151 ALA n 
1 152 GLN n 
1 153 MET n 
1 154 GLN n 
1 155 PRO n 
1 156 SER n 
1 157 LEU n 
1 158 PRO n 
1 159 LEU n 
1 160 GLN n 
1 161 PHE n 
1 162 LEU n 
1 163 VAL n 
1 164 TRP n 
1 165 VAL n 
1 166 THR n 
1 167 PHE n 
1 168 PRO n 
1 169 LEU n 
1 170 VAL n 
1 171 LEU n 
1 172 ILE n 
1 173 LEU n 
1 174 PHE n 
1 175 SER n 
1 176 ALA n 
1 177 LEU n 
1 178 PHE n 
1 179 CYS n 
1 180 HIS n 
1 181 LEU n 
1 182 ILE n 
1 183 SER n 
1 184 PRO n 
1 185 GLN n 
1 186 ALA n 
1 187 VAL n 
1 188 GLY n 
1 189 SER n 
1 190 GLY n 
1 191 ILE n 
1 192 PRO n 
1 193 GLU n 
1 194 MET n 
1 195 LYS n 
1 196 THR n 
1 197 ILE n 
1 198 LEU n 
1 199 ARG n 
1 200 GLY n 
1 201 VAL n 
1 202 VAL n 
1 203 LEU n 
1 204 LYS n 
1 205 GLU n 
1 206 TYR n 
1 207 LEU n 
1 208 THR n 
1 209 MET n 
1 210 LYS n 
1 211 ALA n 
1 212 PHE n 
1 213 VAL n 
1 214 ALA n 
1 215 LYS n 
1 216 VAL n 
1 217 VAL n 
1 218 ALA n 
1 219 LEU n 
1 220 THR n 
1 221 ALA n 
1 222 GLY n 
1 223 LEU n 
1 224 GLY n 
1 225 SER n 
1 226 GLY n 
1 227 ILE n 
1 228 PRO n 
1 229 VAL n 
1 230 GLY n 
1 231 LYS n 
1 232 GLU n 
1 233 GLY n 
1 234 PRO n 
1 235 PHE n 
1 236 VAL n 
1 237 HIS n 
1 238 ILE n 
1 239 ALA n 
1 240 SER n 
1 241 ILE n 
1 242 CYS n 
1 243 ALA n 
1 244 ALA n 
1 245 VAL n 
1 246 LEU n 
1 247 SER n 
1 248 LYS n 
1 249 PHE n 
1 250 MET n 
1 251 SER n 
1 252 VAL n 
1 253 PHE n 
1 254 CYS n 
1 255 GLY n 
1 256 VAL n 
1 257 TYR n 
1 258 GLU n 
1 259 GLN n 
1 260 PRO n 
1 261 TYR n 
1 262 TYR n 
1 263 TYR n 
1 264 SER n 
1 265 ASP n 
1 266 ILE n 
1 267 LEU n 
1 268 THR n 
1 269 VAL n 
1 270 GLY n 
1 271 CYS n 
1 272 ALA n 
1 273 VAL n 
1 274 GLY n 
1 275 VAL n 
1 276 GLY n 
1 277 CYS n 
1 278 CYS n 
1 279 PHE n 
1 280 GLY n 
1 281 THR n 
1 282 PRO n 
1 283 LEU n 
1 284 GLY n 
1 285 GLY n 
1 286 VAL n 
1 287 LEU n 
1 288 PHE n 
1 289 SER n 
1 290 ILE n 
1 291 GLU n 
1 292 VAL n 
1 293 THR n 
1 294 SER n 
1 295 THR n 
1 296 TYR n 
1 297 PHE n 
1 298 ALA n 
1 299 VAL n 
1 300 ARG n 
1 301 ASN n 
1 302 TYR n 
1 303 TRP n 
1 304 ARG n 
1 305 GLY n 
1 306 PHE n 
1 307 PHE n 
1 308 ALA n 
1 309 ALA n 
1 310 THR n 
1 311 PHE n 
1 312 SER n 
1 313 ALA n 
1 314 PHE n 
1 315 VAL n 
1 316 PHE n 
1 317 ARG n 
1 318 VAL n 
1 319 LEU n 
1 320 ALA n 
1 321 VAL n 
1 322 TRP n 
1 323 ASN n 
1 324 LYS n 
1 325 ASP n 
1 326 ALA n 
1 327 VAL n 
1 328 THR n 
1 329 ILE n 
1 330 THR n 
1 331 ALA n 
1 332 LEU n 
1 333 PHE n 
1 334 ARG n 
1 335 THR n 
1 336 ASN n 
1 337 PHE n 
1 338 ARG n 
1 339 MET n 
1 340 ASP n 
1 341 PHE n 
1 342 PRO n 
1 343 PHE n 
1 344 ASP n 
1 345 LEU n 
1 346 LYS n 
1 347 GLU n 
1 348 LEU n 
1 349 PRO n 
1 350 ALA n 
1 351 PHE n 
1 352 ALA n 
1 353 ALA n 
1 354 ILE n 
1 355 GLY n 
1 356 ILE n 
1 357 CYS n 
1 358 CYS n 
1 359 GLY n 
1 360 LEU n 
1 361 LEU n 
1 362 GLY n 
1 363 ALA n 
1 364 VAL n 
1 365 PHE n 
1 366 VAL n 
1 367 TYR n 
1 368 LEU n 
1 369 HIS n 
1 370 ARG n 
1 371 GLN n 
1 372 VAL n 
1 373 MET n 
1 374 LEU n 
1 375 GLY n 
1 376 VAL n 
1 377 ARG n 
1 378 LYS n 
1 379 HIS n 
1 380 LYS n 
1 381 ALA n 
1 382 LEU n 
1 383 SER n 
1 384 GLN n 
1 385 PHE n 
1 386 LEU n 
1 387 ALA n 
1 388 LYS n 
1 389 HIS n 
1 390 ARG n 
1 391 LEU n 
1 392 LEU n 
1 393 TYR n 
1 394 PRO n 
1 395 GLY n 
1 396 ILE n 
1 397 VAL n 
1 398 THR n 
1 399 PHE n 
1 400 VAL n 
1 401 ILE n 
1 402 ALA n 
1 403 SER n 
1 404 PHE n 
1 405 THR n 
1 406 PHE n 
1 407 PRO n 
1 408 PRO n 
1 409 GLY n 
1 410 MET n 
1 411 GLY n 
1 412 GLN n 
1 413 PHE n 
1 414 MET n 
1 415 ALA n 
1 416 GLY n 
1 417 GLU n 
1 418 LEU n 
1 419 MET n 
1 420 PRO n 
1 421 ARG n 
1 422 GLU n 
1 423 ALA n 
1 424 ILE n 
1 425 SER n 
1 426 THR n 
1 427 LEU n 
1 428 PHE n 
1 429 ASP n 
1 430 ASN n 
1 431 ASN n 
1 432 THR n 
1 433 TRP n 
1 434 VAL n 
1 435 LYS n 
1 436 HIS n 
1 437 ALA n 
1 438 GLY n 
1 439 ASP n 
1 440 PRO n 
1 441 GLU n 
1 442 SER n 
1 443 LEU n 
1 444 GLY n 
1 445 GLN n 
1 446 SER n 
1 447 ALA n 
1 448 VAL n 
1 449 TRP n 
1 450 ILE n 
1 451 HIS n 
1 452 PRO n 
1 453 ARG n 
1 454 VAL n 
1 455 ASN n 
1 456 VAL n 
1 457 VAL n 
1 458 ILE n 
1 459 ILE n 
1 460 ILE n 
1 461 PHE n 
1 462 LEU n 
1 463 PHE n 
1 464 PHE n 
1 465 VAL n 
1 466 MET n 
1 467 LYS n 
1 468 PHE n 
1 469 TRP n 
1 470 MET n 
1 471 SER n 
1 472 ILE n 
1 473 VAL n 
1 474 ALA n 
1 475 THR n 
1 476 THR n 
1 477 MET n 
1 478 PRO n 
1 479 ILE n 
1 480 PRO n 
1 481 CYS n 
1 482 GLY n 
1 483 GLY n 
1 484 PHE n 
1 485 MET n 
1 486 PRO n 
1 487 VAL n 
1 488 PHE n 
1 489 VAL n 
1 490 LEU n 
1 491 GLY n 
1 492 ALA n 
1 493 ALA n 
1 494 PHE n 
1 495 GLY n 
1 496 ARG n 
1 497 LEU n 
1 498 VAL n 
1 499 GLY n 
1 500 GLU n 
1 501 ILE n 
1 502 MET n 
1 503 ALA n 
1 504 MET n 
1 505 LEU n 
1 506 PHE n 
1 507 PRO n 
1 508 ASP n 
1 509 GLY n 
1 510 ILE n 
1 511 LEU n 
1 512 PHE n 
1 513 ASP n 
1 514 ASP n 
1 515 ILE n 
1 516 ILE n 
1 517 TYR n 
1 518 LYS n 
1 519 ILE n 
1 520 LEU n 
1 521 PRO n 
1 522 GLY n 
1 523 GLY n 
1 524 TYR n 
1 525 ALA n 
1 526 VAL n 
1 527 ILE n 
1 528 GLY n 
1 529 ALA n 
1 530 ALA n 
1 531 ALA n 
1 532 LEU n 
1 533 THR n 
1 534 GLY n 
1 535 ALA n 
1 536 VAL n 
1 537 SER n 
1 538 HIS n 
1 539 THR n 
1 540 VAL n 
1 541 SER n 
1 542 THR n 
1 543 ALA n 
1 544 VAL n 
1 545 ILE n 
1 546 CYS n 
1 547 PHE n 
1 548 GLU n 
1 549 LEU n 
1 550 THR n 
1 551 GLY n 
1 552 GLN n 
1 553 ILE n 
1 554 ALA n 
1 555 HIS n 
1 556 ILE n 
1 557 LEU n 
1 558 PRO n 
1 559 MET n 
1 560 MET n 
1 561 VAL n 
1 562 ALA n 
1 563 VAL n 
1 564 ILE n 
1 565 LEU n 
1 566 ALA n 
1 567 ASN n 
1 568 MET n 
1 569 VAL n 
1 570 ALA n 
1 571 GLN n 
1 572 SER n 
1 573 LEU n 
1 574 GLN n 
1 575 PRO n 
1 576 SER n 
1 577 LEU n 
1 578 TYR n 
1 579 ASP n 
1 580 SER n 
1 581 ILE n 
1 582 ILE n 
1 583 GLN n 
1 584 VAL n 
1 585 LYS n 
1 586 LYS n 
1 587 LEU n 
1 588 PRO n 
1 589 TYR n 
1 590 LEU n 
1 591 PRO n 
1 592 ASP n 
1 593 LEU n 
1 594 GLY n 
1 595 TRP n 
1 596 ASN n 
1 597 GLN n 
1 598 LEU n 
1 599 SER n 
1 600 LYS n 
1 601 TYR n 
1 602 THR n 
1 603 ILE n 
1 604 PHE n 
1 605 VAL n 
1 606 GLU n 
1 607 ASP n 
1 608 ILE n 
1 609 MET n 
1 610 VAL n 
1 611 ARG n 
1 612 ASP n 
1 613 VAL n 
1 614 LYS n 
1 615 PHE n 
1 616 VAL n 
1 617 SER n 
1 618 ALA n 
1 619 SER n 
1 620 TYR n 
1 621 THR n 
1 622 TYR n 
1 623 GLY n 
1 624 GLU n 
1 625 LEU n 
1 626 ARG n 
1 627 THR n 
1 628 LEU n 
1 629 LEU n 
1 630 GLN n 
1 631 THR n 
1 632 THR n 
1 633 THR n 
1 634 VAL n 
1 635 LYS n 
1 636 THR n 
1 637 LEU n 
1 638 PRO n 
1 639 LEU n 
1 640 VAL n 
1 641 ASP n 
1 642 SER n 
1 643 LYS n 
1 644 ASP n 
1 645 SER n 
1 646 MET n 
1 647 ILE n 
1 648 LEU n 
1 649 LEU n 
1 650 GLY n 
1 651 SER n 
1 652 VAL n 
1 653 GLU n 
1 654 ARG n 
1 655 SER n 
1 656 GLU n 
1 657 LEU n 
1 658 GLN n 
1 659 ALA n 
1 660 LEU n 
1 661 LEU n 
1 662 GLN n 
1 663 ARG n 
1 664 HIS n 
1 665 LEU n 
1 666 CYS n 
1 667 PRO n 
1 668 GLU n 
1 669 ARG n 
1 670 ARG n 
1 671 LEU n 
1 672 ARG n 
1 673 ALA n 
1 674 ALA n 
1 675 GLN n 
1 676 GLU n 
1 677 MET n 
1 678 ALA n 
1 679 ARG n 
1 680 LYS n 
1 681 LEU n 
1 682 SER n 
1 683 GLU n 
1 684 LEU n 
1 685 PRO n 
1 686 TYR n 
1 687 ASP n 
1 688 GLY n 
1 689 LYS n 
1 690 ALA n 
1 691 ARG n 
1 692 LEU n 
1 693 ALA n 
1 694 GLY n 
1 695 GLU n 
1 696 GLY n 
1 697 LEU n 
1 698 PRO n 
1 699 GLY n 
1 700 ALA n 
1 701 PRO n 
1 702 PRO n 
1 703 GLY n 
1 704 ARG n 
1 705 PRO n 
1 706 GLU n 
1 707 SER n 
1 708 PHE n 
1 709 ALA n 
1 710 PHE n 
1 711 VAL n 
1 712 ASP n 
1 713 GLU n 
1 714 ASP n 
1 715 GLU n 
1 716 ASP n 
1 717 GLU n 
1 718 ASP n 
1 719 LEU n 
1 720 SER n 
1 721 GLY n 
1 722 LYS n 
1 723 SER n 
1 724 GLU n 
1 725 LEU n 
1 726 PRO n 
1 727 PRO n 
1 728 SER n 
1 729 LEU n 
1 730 ALA n 
1 731 LEU n 
1 732 HIS n 
1 733 PRO n 
1 734 SER n 
1 735 THR n 
1 736 THR n 
1 737 ALA n 
1 738 PRO n 
1 739 LEU n 
1 740 SER n 
1 741 PRO n 
1 742 GLU n 
1 743 GLU n 
1 744 PRO n 
1 745 ASN n 
1 746 GLY n 
1 747 PRO n 
1 748 LEU n 
1 749 PRO n 
1 750 GLY n 
1 751 HIS n 
1 752 LYS n 
1 753 GLN n 
1 754 GLN n 
1 755 PRO n 
1 756 GLU n 
1 757 ALA n 
1 758 PRO n 
1 759 GLU n 
1 760 PRO n 
1 761 ALA n 
1 762 GLY n 
1 763 GLN n 
1 764 ARG n 
1 765 PRO n 
1 766 SER n 
1 767 ILE n 
1 768 PHE n 
1 769 GLN n 
1 770 SER n 
1 771 LEU n 
1 772 LEU n 
1 773 HIS n 
1 774 CYS n 
1 775 LEU n 
1 776 LEU n 
1 777 GLY n 
1 778 ARG n 
1 779 ALA n 
1 780 ARG n 
1 781 PRO n 
1 782 THR n 
1 783 LYS n 
1 784 LYS n 
1 785 LYS n 
1 786 THR n 
1 787 THR n 
1 788 GLN n 
1 789 ASP n 
1 790 SER n 
1 791 THR n 
1 792 ASP n 
1 793 LEU n 
1 794 VAL n 
1 795 ASP n 
1 796 ASN n 
1 797 MET n 
1 798 SER n 
1 799 PRO n 
1 800 GLU n 
1 801 GLU n 
1 802 ILE n 
1 803 GLU n 
1 804 ALA n 
1 805 TRP n 
1 806 GLU n 
1 807 GLN n 
1 808 GLU n 
1 809 GLN n 
1 810 LEU n 
1 811 SER n 
1 812 GLN n 
1 813 PRO n 
1 814 VAL n 
1 815 CYS n 
1 816 PHE n 
1 817 ASP n 
1 818 SER n 
1 819 CYS n 
1 820 CYS n 
1 821 ILE n 
1 822 ASP n 
1 823 GLN n 
1 824 SER n 
1 825 PRO n 
1 826 PHE n 
1 827 GLN n 
1 828 LEU n 
1 829 VAL n 
1 830 GLU n 
1 831 GLN n 
1 832 THR n 
1 833 THR n 
1 834 LEU n 
1 835 HIS n 
1 836 LYS n 
1 837 THR n 
1 838 HIS n 
1 839 THR n 
1 840 LEU n 
1 841 PHE n 
1 842 SER n 
1 843 LEU n 
1 844 LEU n 
1 845 GLY n 
1 846 LEU n 
1 847 HIS n 
1 848 LEU n 
1 849 ALA n 
1 850 TYR n 
1 851 VAL n 
1 852 THR n 
1 853 SER n 
1 854 MET n 
1 855 GLY n 
1 856 LYS n 
1 857 LEU n 
1 858 ARG n 
1 859 GLY n 
1 860 VAL n 
1 861 LEU n 
1 862 ALA n 
1 863 LEU n 
1 864 GLU n 
1 865 GLU n 
1 866 LEU n 
1 867 GLN n 
1 868 LYS n 
1 869 ALA n 
1 870 ILE n 
1 871 GLU n 
1 872 GLY n 
1 873 HIS n 
1 874 THR n 
1 875 LYS n 
1 876 SER n 
1 877 GLY n 
1 878 VAL n 
1 879 GLN n 
1 880 LEU n 
1 881 ARG n 
1 882 PRO n 
1 883 PRO n 
1 884 LEU n 
1 885 ALA n 
1 886 SER n 
1 887 PHE n 
1 888 ARG n 
1 889 ASN n 
1 890 THR n 
1 891 THR n 
1 892 SER n 
1 893 THR n 
1 894 ARG n 
1 895 LYS n 
1 896 SER n 
1 897 THR n 
1 898 GLY n 
1 899 ALA n 
1 900 PRO n 
1 901 PRO n 
1 902 SER n 
1 903 SER n 
1 904 ALA n 
1 905 GLU n 
1 906 ASN n 
1 907 TRP n 
1 908 ASN n 
1 909 LEU n 
1 910 PRO n 
1 911 GLU n 
1 912 ASP n 
1 913 ARG n 
1 914 PRO n 
1 915 GLY n 
1 916 ALA n 
1 917 THR n 
1 918 GLY n 
1 919 THR n 
1 920 GLY n 
1 921 ASP n 
1 922 VAL n 
1 923 ILE n 
1 924 ALA n 
1 925 ALA n 
1 926 SER n 
1 927 PRO n 
1 928 GLU n 
1 929 THR n 
1 930 PRO n 
1 931 VAL n 
1 932 PRO n 
1 933 SER n 
1 934 PRO n 
1 935 SER n 
1 936 PRO n 
1 937 GLU n 
1 938 PRO n 
1 939 PRO n 
1 940 LEU n 
1 941 SER n 
1 942 LEU n 
1 943 ALA n 
1 944 PRO n 
1 945 GLY n 
1 946 LYS n 
1 947 VAL n 
1 948 GLU n 
1 949 GLY n 
1 950 GLU n 
1 951 LEU n 
1 952 GLU n 
1 953 GLU n 
1 954 LEU n 
1 955 GLU n 
1 956 LEU n 
1 957 VAL n 
1 958 GLU n 
1 959 SER n 
1 960 PRO n 
1 961 GLY n 
1 962 LEU n 
1 963 GLU n 
1 964 GLU n 
1 965 GLU n 
1 966 LEU n 
1 967 ALA n 
1 968 ASP n 
1 969 ILE n 
1 970 LEU n 
1 971 GLN n 
1 972 GLY n 
1 973 PRO n 
1 974 SER n 
1 975 LEU n 
1 976 ARG n 
1 977 SER n 
1 978 THR n 
1 979 ASP n 
1 980 GLU n 
1 981 GLU n 
1 982 ASP n 
1 983 GLU n 
1 984 ASP n 
1 985 GLU n 
1 986 LEU n 
1 987 ILE n 
1 988 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   988 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 CLCN1 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE           ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE          ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE        ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'   ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE          ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE         ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'   ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE           ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE         ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE        ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE           ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE            ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE        ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE     ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE           ? 'C5 H9 N O2'     115.130 
SCN non-polymer         . 'THIOCYANATE ION' ? 'C N S -1'       58.082  
SER 'L-peptide linking' y SERINE            ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE         ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN        ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE          ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE            ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLU 2   2   ?   ?   ?   A . n 
A 1 3   GLN 3   3   ?   ?   ?   A . n 
A 1 4   SER 4   4   ?   ?   ?   A . n 
A 1 5   ARG 5   5   ?   ?   ?   A . n 
A 1 6   SER 6   6   ?   ?   ?   A . n 
A 1 7   GLN 7   7   ?   ?   ?   A . n 
A 1 8   GLN 8   8   ?   ?   ?   A . n 
A 1 9   ARG 9   9   ?   ?   ?   A . n 
A 1 10  GLY 10  10  ?   ?   ?   A . n 
A 1 11  GLY 11  11  ?   ?   ?   A . n 
A 1 12  GLU 12  12  ?   ?   ?   A . n 
A 1 13  GLN 13  13  ?   ?   ?   A . n 
A 1 14  SER 14  14  ?   ?   ?   A . n 
A 1 15  TRP 15  15  ?   ?   ?   A . n 
A 1 16  TRP 16  16  ?   ?   ?   A . n 
A 1 17  GLY 17  17  ?   ?   ?   A . n 
A 1 18  SER 18  18  ?   ?   ?   A . n 
A 1 19  ASP 19  19  ?   ?   ?   A . n 
A 1 20  PRO 20  20  ?   ?   ?   A . n 
A 1 21  GLN 21  21  ?   ?   ?   A . n 
A 1 22  TYR 22  22  ?   ?   ?   A . n 
A 1 23  GLN 23  23  ?   ?   ?   A . n 
A 1 24  TYR 24  24  ?   ?   ?   A . n 
A 1 25  MET 25  25  ?   ?   ?   A . n 
A 1 26  PRO 26  26  ?   ?   ?   A . n 
A 1 27  PHE 27  27  ?   ?   ?   A . n 
A 1 28  GLU 28  28  ?   ?   ?   A . n 
A 1 29  HIS 29  29  ?   ?   ?   A . n 
A 1 30  CYS 30  30  ?   ?   ?   A . n 
A 1 31  THR 31  31  ?   ?   ?   A . n 
A 1 32  SER 32  32  ?   ?   ?   A . n 
A 1 33  TYR 33  33  ?   ?   ?   A . n 
A 1 34  GLY 34  34  ?   ?   ?   A . n 
A 1 35  LEU 35  35  ?   ?   ?   A . n 
A 1 36  PRO 36  36  ?   ?   ?   A . n 
A 1 37  SER 37  37  ?   ?   ?   A . n 
A 1 38  GLU 38  38  ?   ?   ?   A . n 
A 1 39  ASN 39  39  ?   ?   ?   A . n 
A 1 40  GLY 40  40  ?   ?   ?   A . n 
A 1 41  GLY 41  41  ?   ?   ?   A . n 
A 1 42  LEU 42  42  ?   ?   ?   A . n 
A 1 43  GLN 43  43  ?   ?   ?   A . n 
A 1 44  HIS 44  44  ?   ?   ?   A . n 
A 1 45  ARG 45  45  ?   ?   ?   A . n 
A 1 46  LEU 46  46  ?   ?   ?   A . n 
A 1 47  ARG 47  47  ?   ?   ?   A . n 
A 1 48  LYS 48  48  ?   ?   ?   A . n 
A 1 49  ASP 49  49  ?   ?   ?   A . n 
A 1 50  ALA 50  50  ?   ?   ?   A . n 
A 1 51  GLY 51  51  ?   ?   ?   A . n 
A 1 52  PRO 52  52  ?   ?   ?   A . n 
A 1 53  ARG 53  53  ?   ?   ?   A . n 
A 1 54  HIS 54  54  ?   ?   ?   A . n 
A 1 55  ASN 55  55  ?   ?   ?   A . n 
A 1 56  VAL 56  56  ?   ?   ?   A . n 
A 1 57  HIS 57  57  ?   ?   ?   A . n 
A 1 58  PRO 58  58  ?   ?   ?   A . n 
A 1 59  THR 59  59  ?   ?   ?   A . n 
A 1 60  GLN 60  60  ?   ?   ?   A . n 
A 1 61  ILE 61  61  ?   ?   ?   A . n 
A 1 62  TYR 62  62  ?   ?   ?   A . n 
A 1 63  GLY 63  63  ?   ?   ?   A . n 
A 1 64  HIS 64  64  ?   ?   ?   A . n 
A 1 65  HIS 65  65  ?   ?   ?   A . n 
A 1 66  LYS 66  66  ?   ?   ?   A . n 
A 1 67  GLU 67  67  ?   ?   ?   A . n 
A 1 68  GLN 68  68  ?   ?   ?   A . n 
A 1 69  PHE 69  69  ?   ?   ?   A . n 
A 1 70  SER 70  70  ?   ?   ?   A . n 
A 1 71  ASP 71  71  ?   ?   ?   A . n 
A 1 72  ARG 72  72  ?   ?   ?   A . n 
A 1 73  GLU 73  73  ?   ?   ?   A . n 
A 1 74  GLN 74  74  ?   ?   ?   A . n 
A 1 75  ASP 75  75  ?   ?   ?   A . n 
A 1 76  ILE 76  76  ?   ?   ?   A . n 
A 1 77  GLY 77  77  ?   ?   ?   A . n 
A 1 78  MET 78  78  ?   ?   ?   A . n 
A 1 79  PRO 79  79  ?   ?   ?   A . n 
A 1 80  LYS 80  80  ?   ?   ?   A . n 
A 1 81  LYS 81  81  ?   ?   ?   A . n 
A 1 82  THR 82  82  ?   ?   ?   A . n 
A 1 83  GLY 83  83  ?   ?   ?   A . n 
A 1 84  SER 84  84  ?   ?   ?   A . n 
A 1 85  SER 85  85  ?   ?   ?   A . n 
A 1 86  SER 86  86  ?   ?   ?   A . n 
A 1 87  THR 87  87  ?   ?   ?   A . n 
A 1 88  VAL 88  88  ?   ?   ?   A . n 
A 1 89  ASP 89  89  ?   ?   ?   A . n 
A 1 90  SER 90  90  ?   ?   ?   A . n 
A 1 91  LYS 91  91  ?   ?   ?   A . n 
A 1 92  ASP 92  92  ?   ?   ?   A . n 
A 1 93  GLU 93  93  ?   ?   ?   A . n 
A 1 94  ASP 94  94  ?   ?   ?   A . n 
A 1 95  HIS 95  95  ?   ?   ?   A . n 
A 1 96  TYR 96  96  ?   ?   ?   A . n 
A 1 97  SER 97  97  ?   ?   ?   A . n 
A 1 98  LYS 98  98  ?   ?   ?   A . n 
A 1 99  CYS 99  99  ?   ?   ?   A . n 
A 1 100 GLN 100 100 ?   ?   ?   A . n 
A 1 101 ASP 101 101 ?   ?   ?   A . n 
A 1 102 CYS 102 102 ?   ?   ?   A . n 
A 1 103 ILE 103 103 ?   ?   ?   A . n 
A 1 104 HIS 104 104 ?   ?   ?   A . n 
A 1 105 ARG 105 105 ?   ?   ?   A . n 
A 1 106 LEU 106 106 ?   ?   ?   A . n 
A 1 107 GLY 107 107 ?   ?   ?   A . n 
A 1 108 GLN 108 108 ?   ?   ?   A . n 
A 1 109 VAL 109 109 ?   ?   ?   A . n 
A 1 110 VAL 110 110 ?   ?   ?   A . n 
A 1 111 ARG 111 111 ?   ?   ?   A . n 
A 1 112 ARG 112 112 ?   ?   ?   A . n 
A 1 113 LYS 113 113 ?   ?   ?   A . n 
A 1 114 LEU 114 114 ?   ?   ?   A . n 
A 1 115 GLY 115 115 115 GLY GLY A . n 
A 1 116 GLU 116 116 116 GLU GLU A . n 
A 1 117 ASP 117 117 117 ASP ASP A . n 
A 1 118 GLY 118 118 118 GLY GLY A . n 
A 1 119 ILE 119 119 119 ILE ILE A . n 
A 1 120 PHE 120 120 120 PHE PHE A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 VAL 122 122 122 VAL VAL A . n 
A 1 123 LEU 123 123 123 LEU LEU A . n 
A 1 124 LEU 124 124 124 LEU LEU A . n 
A 1 125 GLY 125 125 125 GLY GLY A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 LEU 127 127 127 LEU LEU A . n 
A 1 128 MET 128 128 128 MET MET A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 LEU 130 130 130 LEU LEU A . n 
A 1 131 VAL 131 131 131 VAL VAL A . n 
A 1 132 SER 132 132 132 SER SER A . n 
A 1 133 TRP 133 133 133 TRP TRP A . n 
A 1 134 SER 134 134 134 SER SER A . n 
A 1 135 MET 135 135 135 MET MET A . n 
A 1 136 GLY 136 136 136 GLY GLY A . n 
A 1 137 TYR 137 137 137 TYR TYR A . n 
A 1 138 VAL 138 138 138 VAL VAL A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 LYS 141 141 141 LYS LYS A . n 
A 1 142 SER 142 142 142 SER SER A . n 
A 1 143 LEU 143 143 143 LEU LEU A . n 
A 1 144 GLN 144 144 144 GLN GLN A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 TYR 146 146 146 TYR TYR A . n 
A 1 147 LYS 147 147 147 LYS LYS A . n 
A 1 148 TRP 148 148 148 TRP TRP A . n 
A 1 149 SER 149 149 149 SER SER A . n 
A 1 150 TYR 150 150 150 TYR TYR A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 GLN 152 152 152 GLN GLN A . n 
A 1 153 MET 153 153 153 MET MET A . n 
A 1 154 GLN 154 154 154 GLN GLN A . n 
A 1 155 PRO 155 155 155 PRO PRO A . n 
A 1 156 SER 156 156 156 SER SER A . n 
A 1 157 LEU 157 157 157 LEU LEU A . n 
A 1 158 PRO 158 158 158 PRO PRO A . n 
A 1 159 LEU 159 159 159 LEU LEU A . n 
A 1 160 GLN 160 160 160 GLN GLN A . n 
A 1 161 PHE 161 161 161 PHE PHE A . n 
A 1 162 LEU 162 162 162 LEU LEU A . n 
A 1 163 VAL 163 163 163 VAL VAL A . n 
A 1 164 TRP 164 164 164 TRP TRP A . n 
A 1 165 VAL 165 165 165 VAL VAL A . n 
A 1 166 THR 166 166 166 THR THR A . n 
A 1 167 PHE 167 167 167 PHE PHE A . n 
A 1 168 PRO 168 168 168 PRO PRO A . n 
A 1 169 LEU 169 169 169 LEU LEU A . n 
A 1 170 VAL 170 170 170 VAL VAL A . n 
A 1 171 LEU 171 171 171 LEU LEU A . n 
A 1 172 ILE 172 172 172 ILE ILE A . n 
A 1 173 LEU 173 173 173 LEU LEU A . n 
A 1 174 PHE 174 174 174 PHE PHE A . n 
A 1 175 SER 175 175 175 SER SER A . n 
A 1 176 ALA 176 176 176 ALA ALA A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 PHE 178 178 178 PHE PHE A . n 
A 1 179 CYS 179 179 179 CYS CYS A . n 
A 1 180 HIS 180 180 180 HIS HIS A . n 
A 1 181 LEU 181 181 181 LEU LEU A . n 
A 1 182 ILE 182 182 182 ILE ILE A . n 
A 1 183 SER 183 183 183 SER SER A . n 
A 1 184 PRO 184 184 184 PRO PRO A . n 
A 1 185 GLN 185 185 185 GLN GLN A . n 
A 1 186 ALA 186 186 186 ALA ALA A . n 
A 1 187 VAL 187 187 187 VAL VAL A . n 
A 1 188 GLY 188 188 188 GLY GLY A . n 
A 1 189 SER 189 189 189 SER SER A . n 
A 1 190 GLY 190 190 190 GLY GLY A . n 
A 1 191 ILE 191 191 191 ILE ILE A . n 
A 1 192 PRO 192 192 192 PRO PRO A . n 
A 1 193 GLU 193 193 193 GLU GLU A . n 
A 1 194 MET 194 194 194 MET MET A . n 
A 1 195 LYS 195 195 195 LYS LYS A . n 
A 1 196 THR 196 196 196 THR THR A . n 
A 1 197 ILE 197 197 197 ILE ILE A . n 
A 1 198 LEU 198 198 198 LEU LEU A . n 
A 1 199 ARG 199 199 199 ARG ARG A . n 
A 1 200 GLY 200 200 200 GLY GLY A . n 
A 1 201 VAL 201 201 201 VAL VAL A . n 
A 1 202 VAL 202 202 202 VAL VAL A . n 
A 1 203 LEU 203 203 203 LEU LEU A . n 
A 1 204 LYS 204 204 204 LYS LYS A . n 
A 1 205 GLU 205 205 205 GLU GLU A . n 
A 1 206 TYR 206 206 206 TYR TYR A . n 
A 1 207 LEU 207 207 207 LEU LEU A . n 
A 1 208 THR 208 208 208 THR THR A . n 
A 1 209 MET 209 209 209 MET MET A . n 
A 1 210 LYS 210 210 210 LYS LYS A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 PHE 212 212 212 PHE PHE A . n 
A 1 213 VAL 213 213 213 VAL VAL A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 LYS 215 215 215 LYS LYS A . n 
A 1 216 VAL 216 216 216 VAL VAL A . n 
A 1 217 VAL 217 217 217 VAL VAL A . n 
A 1 218 ALA 218 218 218 ALA ALA A . n 
A 1 219 LEU 219 219 219 LEU LEU A . n 
A 1 220 THR 220 220 220 THR THR A . n 
A 1 221 ALA 221 221 221 ALA ALA A . n 
A 1 222 GLY 222 222 222 GLY GLY A . n 
A 1 223 LEU 223 223 223 LEU LEU A . n 
A 1 224 GLY 224 224 224 GLY GLY A . n 
A 1 225 SER 225 225 225 SER SER A . n 
A 1 226 GLY 226 226 226 GLY GLY A . n 
A 1 227 ILE 227 227 227 ILE ILE A . n 
A 1 228 PRO 228 228 228 PRO PRO A . n 
A 1 229 VAL 229 229 229 VAL VAL A . n 
A 1 230 GLY 230 230 230 GLY GLY A . n 
A 1 231 LYS 231 231 231 LYS LYS A . n 
A 1 232 GLU 232 232 232 GLU GLU A . n 
A 1 233 GLY 233 233 233 GLY GLY A . n 
A 1 234 PRO 234 234 234 PRO PRO A . n 
A 1 235 PHE 235 235 235 PHE PHE A . n 
A 1 236 VAL 236 236 236 VAL VAL A . n 
A 1 237 HIS 237 237 237 HIS HIS A . n 
A 1 238 ILE 238 238 238 ILE ILE A . n 
A 1 239 ALA 239 239 239 ALA ALA A . n 
A 1 240 SER 240 240 240 SER SER A . n 
A 1 241 ILE 241 241 241 ILE ILE A . n 
A 1 242 CYS 242 242 242 CYS CYS A . n 
A 1 243 ALA 243 243 243 ALA ALA A . n 
A 1 244 ALA 244 244 244 ALA ALA A . n 
A 1 245 VAL 245 245 245 VAL VAL A . n 
A 1 246 LEU 246 246 246 LEU LEU A . n 
A 1 247 SER 247 247 247 SER SER A . n 
A 1 248 LYS 248 248 248 LYS LYS A . n 
A 1 249 PHE 249 249 249 PHE PHE A . n 
A 1 250 MET 250 250 250 MET MET A . n 
A 1 251 SER 251 251 251 SER SER A . n 
A 1 252 VAL 252 252 252 VAL VAL A . n 
A 1 253 PHE 253 253 253 PHE PHE A . n 
A 1 254 CYS 254 254 ?   ?   ?   A . n 
A 1 255 GLY 255 255 ?   ?   ?   A . n 
A 1 256 VAL 256 256 ?   ?   ?   A . n 
A 1 257 TYR 257 257 ?   ?   ?   A . n 
A 1 258 GLU 258 258 ?   ?   ?   A . n 
A 1 259 GLN 259 259 ?   ?   ?   A . n 
A 1 260 PRO 260 260 ?   ?   ?   A . n 
A 1 261 TYR 261 261 ?   ?   ?   A . n 
A 1 262 TYR 262 262 262 TYR TYR A . n 
A 1 263 TYR 263 263 263 TYR TYR A . n 
A 1 264 SER 264 264 264 SER SER A . n 
A 1 265 ASP 265 265 265 ASP ASP A . n 
A 1 266 ILE 266 266 266 ILE ILE A . n 
A 1 267 LEU 267 267 267 LEU LEU A . n 
A 1 268 THR 268 268 268 THR THR A . n 
A 1 269 VAL 269 269 269 VAL VAL A . n 
A 1 270 GLY 270 270 270 GLY GLY A . n 
A 1 271 CYS 271 271 271 CYS CYS A . n 
A 1 272 ALA 272 272 272 ALA ALA A . n 
A 1 273 VAL 273 273 273 VAL VAL A . n 
A 1 274 GLY 274 274 274 GLY GLY A . n 
A 1 275 VAL 275 275 275 VAL VAL A . n 
A 1 276 GLY 276 276 276 GLY GLY A . n 
A 1 277 CYS 277 277 277 CYS CYS A . n 
A 1 278 CYS 278 278 278 CYS CYS A . n 
A 1 279 PHE 279 279 279 PHE PHE A . n 
A 1 280 GLY 280 280 280 GLY GLY A . n 
A 1 281 THR 281 281 281 THR THR A . n 
A 1 282 PRO 282 282 282 PRO PRO A . n 
A 1 283 LEU 283 283 283 LEU LEU A . n 
A 1 284 GLY 284 284 284 GLY GLY A . n 
A 1 285 GLY 285 285 285 GLY GLY A . n 
A 1 286 VAL 286 286 286 VAL VAL A . n 
A 1 287 LEU 287 287 287 LEU LEU A . n 
A 1 288 PHE 288 288 288 PHE PHE A . n 
A 1 289 SER 289 289 289 SER SER A . n 
A 1 290 ILE 290 290 290 ILE ILE A . n 
A 1 291 GLU 291 291 291 GLU GLU A . n 
A 1 292 VAL 292 292 292 VAL VAL A . n 
A 1 293 THR 293 293 293 THR THR A . n 
A 1 294 SER 294 294 294 SER SER A . n 
A 1 295 THR 295 295 295 THR THR A . n 
A 1 296 TYR 296 296 296 TYR TYR A . n 
A 1 297 PHE 297 297 297 PHE PHE A . n 
A 1 298 ALA 298 298 298 ALA ALA A . n 
A 1 299 VAL 299 299 299 VAL VAL A . n 
A 1 300 ARG 300 300 300 ARG ARG A . n 
A 1 301 ASN 301 301 301 ASN ASN A . n 
A 1 302 TYR 302 302 302 TYR TYR A . n 
A 1 303 TRP 303 303 303 TRP TRP A . n 
A 1 304 ARG 304 304 304 ARG ARG A . n 
A 1 305 GLY 305 305 305 GLY GLY A . n 
A 1 306 PHE 306 306 306 PHE PHE A . n 
A 1 307 PHE 307 307 307 PHE PHE A . n 
A 1 308 ALA 308 308 308 ALA ALA A . n 
A 1 309 ALA 309 309 309 ALA ALA A . n 
A 1 310 THR 310 310 310 THR THR A . n 
A 1 311 PHE 311 311 311 PHE PHE A . n 
A 1 312 SER 312 312 312 SER SER A . n 
A 1 313 ALA 313 313 313 ALA ALA A . n 
A 1 314 PHE 314 314 314 PHE PHE A . n 
A 1 315 VAL 315 315 315 VAL VAL A . n 
A 1 316 PHE 316 316 316 PHE PHE A . n 
A 1 317 ARG 317 317 317 ARG ARG A . n 
A 1 318 VAL 318 318 318 VAL VAL A . n 
A 1 319 LEU 319 319 319 LEU LEU A . n 
A 1 320 ALA 320 320 320 ALA ALA A . n 
A 1 321 VAL 321 321 321 VAL VAL A . n 
A 1 322 TRP 322 322 322 TRP TRP A . n 
A 1 323 ASN 323 323 323 ASN ASN A . n 
A 1 324 LYS 324 324 324 LYS LYS A . n 
A 1 325 ASP 325 325 325 ASP ASP A . n 
A 1 326 ALA 326 326 326 ALA ALA A . n 
A 1 327 VAL 327 327 327 VAL VAL A . n 
A 1 328 THR 328 328 328 THR THR A . n 
A 1 329 ILE 329 329 329 ILE ILE A . n 
A 1 330 THR 330 330 330 THR THR A . n 
A 1 331 ALA 331 331 331 ALA ALA A . n 
A 1 332 LEU 332 332 332 LEU LEU A . n 
A 1 333 PHE 333 333 333 PHE PHE A . n 
A 1 334 ARG 334 334 334 ARG ARG A . n 
A 1 335 THR 335 335 335 THR THR A . n 
A 1 336 ASN 336 336 336 ASN ASN A . n 
A 1 337 PHE 337 337 337 PHE PHE A . n 
A 1 338 ARG 338 338 338 ARG ARG A . n 
A 1 339 MET 339 339 339 MET MET A . n 
A 1 340 ASP 340 340 340 ASP ASP A . n 
A 1 341 PHE 341 341 341 PHE PHE A . n 
A 1 342 PRO 342 342 342 PRO PRO A . n 
A 1 343 PHE 343 343 343 PHE PHE A . n 
A 1 344 ASP 344 344 344 ASP ASP A . n 
A 1 345 LEU 345 345 345 LEU LEU A . n 
A 1 346 LYS 346 346 346 LYS LYS A . n 
A 1 347 GLU 347 347 347 GLU GLU A . n 
A 1 348 LEU 348 348 348 LEU LEU A . n 
A 1 349 PRO 349 349 349 PRO PRO A . n 
A 1 350 ALA 350 350 350 ALA ALA A . n 
A 1 351 PHE 351 351 351 PHE PHE A . n 
A 1 352 ALA 352 352 352 ALA ALA A . n 
A 1 353 ALA 353 353 353 ALA ALA A . n 
A 1 354 ILE 354 354 354 ILE ILE A . n 
A 1 355 GLY 355 355 355 GLY GLY A . n 
A 1 356 ILE 356 356 356 ILE ILE A . n 
A 1 357 CYS 357 357 357 CYS CYS A . n 
A 1 358 CYS 358 358 358 CYS CYS A . n 
A 1 359 GLY 359 359 359 GLY GLY A . n 
A 1 360 LEU 360 360 360 LEU LEU A . n 
A 1 361 LEU 361 361 361 LEU LEU A . n 
A 1 362 GLY 362 362 362 GLY GLY A . n 
A 1 363 ALA 363 363 363 ALA ALA A . n 
A 1 364 VAL 364 364 364 VAL VAL A . n 
A 1 365 PHE 365 365 365 PHE PHE A . n 
A 1 366 VAL 366 366 366 VAL VAL A . n 
A 1 367 TYR 367 367 367 TYR TYR A . n 
A 1 368 LEU 368 368 368 LEU LEU A . n 
A 1 369 HIS 369 369 369 HIS HIS A . n 
A 1 370 ARG 370 370 370 ARG ARG A . n 
A 1 371 GLN 371 371 371 GLN GLN A . n 
A 1 372 VAL 372 372 372 VAL VAL A . n 
A 1 373 MET 373 373 373 MET MET A . n 
A 1 374 LEU 374 374 374 LEU LEU A . n 
A 1 375 GLY 375 375 375 GLY GLY A . n 
A 1 376 VAL 376 376 376 VAL VAL A . n 
A 1 377 ARG 377 377 377 ARG ARG A . n 
A 1 378 LYS 378 378 378 LYS LYS A . n 
A 1 379 HIS 379 379 379 HIS HIS A . n 
A 1 380 LYS 380 380 380 LYS LYS A . n 
A 1 381 ALA 381 381 381 ALA ALA A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 SER 383 383 383 SER SER A . n 
A 1 384 GLN 384 384 384 GLN GLN A . n 
A 1 385 PHE 385 385 385 PHE PHE A . n 
A 1 386 LEU 386 386 386 LEU LEU A . n 
A 1 387 ALA 387 387 387 ALA ALA A . n 
A 1 388 LYS 388 388 388 LYS LYS A . n 
A 1 389 HIS 389 389 389 HIS HIS A . n 
A 1 390 ARG 390 390 390 ARG ARG A . n 
A 1 391 LEU 391 391 391 LEU LEU A . n 
A 1 392 LEU 392 392 392 LEU LEU A . n 
A 1 393 TYR 393 393 393 TYR TYR A . n 
A 1 394 PRO 394 394 394 PRO PRO A . n 
A 1 395 GLY 395 395 395 GLY GLY A . n 
A 1 396 ILE 396 396 396 ILE ILE A . n 
A 1 397 VAL 397 397 397 VAL VAL A . n 
A 1 398 THR 398 398 398 THR THR A . n 
A 1 399 PHE 399 399 399 PHE PHE A . n 
A 1 400 VAL 400 400 400 VAL VAL A . n 
A 1 401 ILE 401 401 401 ILE ILE A . n 
A 1 402 ALA 402 402 402 ALA ALA A . n 
A 1 403 SER 403 403 403 SER SER A . n 
A 1 404 PHE 404 404 404 PHE PHE A . n 
A 1 405 THR 405 405 405 THR THR A . n 
A 1 406 PHE 406 406 406 PHE PHE A . n 
A 1 407 PRO 407 407 407 PRO PRO A . n 
A 1 408 PRO 408 408 408 PRO PRO A . n 
A 1 409 GLY 409 409 409 GLY GLY A . n 
A 1 410 MET 410 410 410 MET MET A . n 
A 1 411 GLY 411 411 411 GLY GLY A . n 
A 1 412 GLN 412 412 412 GLN GLN A . n 
A 1 413 PHE 413 413 413 PHE PHE A . n 
A 1 414 MET 414 414 414 MET MET A . n 
A 1 415 ALA 415 415 415 ALA ALA A . n 
A 1 416 GLY 416 416 416 GLY GLY A . n 
A 1 417 GLU 417 417 417 GLU GLU A . n 
A 1 418 LEU 418 418 418 LEU LEU A . n 
A 1 419 MET 419 419 419 MET MET A . n 
A 1 420 PRO 420 420 420 PRO PRO A . n 
A 1 421 ARG 421 421 421 ARG ARG A . n 
A 1 422 GLU 422 422 422 GLU GLU A . n 
A 1 423 ALA 423 423 423 ALA ALA A . n 
A 1 424 ILE 424 424 424 ILE ILE A . n 
A 1 425 SER 425 425 425 SER SER A . n 
A 1 426 THR 426 426 426 THR THR A . n 
A 1 427 LEU 427 427 427 LEU LEU A . n 
A 1 428 PHE 428 428 428 PHE PHE A . n 
A 1 429 ASP 429 429 429 ASP ASP A . n 
A 1 430 ASN 430 430 430 ASN ASN A . n 
A 1 431 ASN 431 431 431 ASN ASN A . n 
A 1 432 THR 432 432 432 THR THR A . n 
A 1 433 TRP 433 433 433 TRP TRP A . n 
A 1 434 VAL 434 434 434 VAL VAL A . n 
A 1 435 LYS 435 435 435 LYS LYS A . n 
A 1 436 HIS 436 436 436 HIS HIS A . n 
A 1 437 ALA 437 437 437 ALA ALA A . n 
A 1 438 GLY 438 438 438 GLY GLY A . n 
A 1 439 ASP 439 439 439 ASP ASP A . n 
A 1 440 PRO 440 440 440 PRO PRO A . n 
A 1 441 GLU 441 441 441 GLU GLU A . n 
A 1 442 SER 442 442 442 SER SER A . n 
A 1 443 LEU 443 443 443 LEU LEU A . n 
A 1 444 GLY 444 444 444 GLY GLY A . n 
A 1 445 GLN 445 445 445 GLN GLN A . n 
A 1 446 SER 446 446 446 SER SER A . n 
A 1 447 ALA 447 447 447 ALA ALA A . n 
A 1 448 VAL 448 448 448 VAL VAL A . n 
A 1 449 TRP 449 449 449 TRP TRP A . n 
A 1 450 ILE 450 450 450 ILE ILE A . n 
A 1 451 HIS 451 451 451 HIS HIS A . n 
A 1 452 PRO 452 452 452 PRO PRO A . n 
A 1 453 ARG 453 453 453 ARG ARG A . n 
A 1 454 VAL 454 454 454 VAL VAL A . n 
A 1 455 ASN 455 455 455 ASN ASN A . n 
A 1 456 VAL 456 456 456 VAL VAL A . n 
A 1 457 VAL 457 457 457 VAL VAL A . n 
A 1 458 ILE 458 458 458 ILE ILE A . n 
A 1 459 ILE 459 459 459 ILE ILE A . n 
A 1 460 ILE 460 460 460 ILE ILE A . n 
A 1 461 PHE 461 461 461 PHE PHE A . n 
A 1 462 LEU 462 462 462 LEU LEU A . n 
A 1 463 PHE 463 463 463 PHE PHE A . n 
A 1 464 PHE 464 464 464 PHE PHE A . n 
A 1 465 VAL 465 465 465 VAL VAL A . n 
A 1 466 MET 466 466 466 MET MET A . n 
A 1 467 LYS 467 467 467 LYS LYS A . n 
A 1 468 PHE 468 468 468 PHE PHE A . n 
A 1 469 TRP 469 469 469 TRP TRP A . n 
A 1 470 MET 470 470 470 MET MET A . n 
A 1 471 SER 471 471 471 SER SER A . n 
A 1 472 ILE 472 472 472 ILE ILE A . n 
A 1 473 VAL 473 473 473 VAL VAL A . n 
A 1 474 ALA 474 474 474 ALA ALA A . n 
A 1 475 THR 475 475 475 THR THR A . n 
A 1 476 THR 476 476 476 THR THR A . n 
A 1 477 MET 477 477 477 MET MET A . n 
A 1 478 PRO 478 478 478 PRO PRO A . n 
A 1 479 ILE 479 479 479 ILE ILE A . n 
A 1 480 PRO 480 480 480 PRO PRO A . n 
A 1 481 CYS 481 481 481 CYS CYS A . n 
A 1 482 GLY 482 482 482 GLY GLY A . n 
A 1 483 GLY 483 483 483 GLY GLY A . n 
A 1 484 PHE 484 484 484 PHE PHE A . n 
A 1 485 MET 485 485 485 MET MET A . n 
A 1 486 PRO 486 486 486 PRO PRO A . n 
A 1 487 VAL 487 487 487 VAL VAL A . n 
A 1 488 PHE 488 488 488 PHE PHE A . n 
A 1 489 VAL 489 489 489 VAL VAL A . n 
A 1 490 LEU 490 490 490 LEU LEU A . n 
A 1 491 GLY 491 491 491 GLY GLY A . n 
A 1 492 ALA 492 492 492 ALA ALA A . n 
A 1 493 ALA 493 493 493 ALA ALA A . n 
A 1 494 PHE 494 494 494 PHE PHE A . n 
A 1 495 GLY 495 495 495 GLY GLY A . n 
A 1 496 ARG 496 496 496 ARG ARG A . n 
A 1 497 LEU 497 497 497 LEU LEU A . n 
A 1 498 VAL 498 498 498 VAL VAL A . n 
A 1 499 GLY 499 499 499 GLY GLY A . n 
A 1 500 GLU 500 500 500 GLU GLU A . n 
A 1 501 ILE 501 501 501 ILE ILE A . n 
A 1 502 MET 502 502 502 MET MET A . n 
A 1 503 ALA 503 503 503 ALA ALA A . n 
A 1 504 MET 504 504 504 MET MET A . n 
A 1 505 LEU 505 505 505 LEU LEU A . n 
A 1 506 PHE 506 506 506 PHE PHE A . n 
A 1 507 PRO 507 507 507 PRO PRO A . n 
A 1 508 ASP 508 508 508 ASP ASP A . n 
A 1 509 GLY 509 509 509 GLY GLY A . n 
A 1 510 ILE 510 510 510 ILE ILE A . n 
A 1 511 LEU 511 511 511 LEU LEU A . n 
A 1 512 PHE 512 512 512 PHE PHE A . n 
A 1 513 ASP 513 513 513 ASP ASP A . n 
A 1 514 ASP 514 514 514 ASP ASP A . n 
A 1 515 ILE 515 515 515 ILE ILE A . n 
A 1 516 ILE 516 516 516 ILE ILE A . n 
A 1 517 TYR 517 517 517 TYR TYR A . n 
A 1 518 LYS 518 518 518 LYS LYS A . n 
A 1 519 ILE 519 519 519 ILE ILE A . n 
A 1 520 LEU 520 520 520 LEU LEU A . n 
A 1 521 PRO 521 521 521 PRO PRO A . n 
A 1 522 GLY 522 522 522 GLY GLY A . n 
A 1 523 GLY 523 523 523 GLY GLY A . n 
A 1 524 TYR 524 524 524 TYR TYR A . n 
A 1 525 ALA 525 525 525 ALA ALA A . n 
A 1 526 VAL 526 526 526 VAL VAL A . n 
A 1 527 ILE 527 527 527 ILE ILE A . n 
A 1 528 GLY 528 528 528 GLY GLY A . n 
A 1 529 ALA 529 529 529 ALA ALA A . n 
A 1 530 ALA 530 530 530 ALA ALA A . n 
A 1 531 ALA 531 531 531 ALA ALA A . n 
A 1 532 LEU 532 532 532 LEU LEU A . n 
A 1 533 THR 533 533 533 THR THR A . n 
A 1 534 GLY 534 534 534 GLY GLY A . n 
A 1 535 ALA 535 535 535 ALA ALA A . n 
A 1 536 VAL 536 536 536 VAL VAL A . n 
A 1 537 SER 537 537 537 SER SER A . n 
A 1 538 HIS 538 538 538 HIS HIS A . n 
A 1 539 THR 539 539 539 THR THR A . n 
A 1 540 VAL 540 540 540 VAL VAL A . n 
A 1 541 SER 541 541 541 SER SER A . n 
A 1 542 THR 542 542 542 THR THR A . n 
A 1 543 ALA 543 543 543 ALA ALA A . n 
A 1 544 VAL 544 544 544 VAL VAL A . n 
A 1 545 ILE 545 545 545 ILE ILE A . n 
A 1 546 CYS 546 546 546 CYS CYS A . n 
A 1 547 PHE 547 547 547 PHE PHE A . n 
A 1 548 GLU 548 548 548 GLU GLU A . n 
A 1 549 LEU 549 549 549 LEU LEU A . n 
A 1 550 THR 550 550 550 THR THR A . n 
A 1 551 GLY 551 551 551 GLY GLY A . n 
A 1 552 GLN 552 552 552 GLN GLN A . n 
A 1 553 ILE 553 553 553 ILE ILE A . n 
A 1 554 ALA 554 554 554 ALA ALA A . n 
A 1 555 HIS 555 555 555 HIS HIS A . n 
A 1 556 ILE 556 556 556 ILE ILE A . n 
A 1 557 LEU 557 557 557 LEU LEU A . n 
A 1 558 PRO 558 558 558 PRO PRO A . n 
A 1 559 MET 559 559 559 MET MET A . n 
A 1 560 MET 560 560 560 MET MET A . n 
A 1 561 VAL 561 561 561 VAL VAL A . n 
A 1 562 ALA 562 562 562 ALA ALA A . n 
A 1 563 VAL 563 563 563 VAL VAL A . n 
A 1 564 ILE 564 564 564 ILE ILE A . n 
A 1 565 LEU 565 565 565 LEU LEU A . n 
A 1 566 ALA 566 566 566 ALA ALA A . n 
A 1 567 ASN 567 567 567 ASN ASN A . n 
A 1 568 MET 568 568 568 MET MET A . n 
A 1 569 VAL 569 569 569 VAL VAL A . n 
A 1 570 ALA 570 570 570 ALA ALA A . n 
A 1 571 GLN 571 571 571 GLN GLN A . n 
A 1 572 SER 572 572 572 SER SER A . n 
A 1 573 LEU 573 573 573 LEU LEU A . n 
A 1 574 GLN 574 574 574 GLN GLN A . n 
A 1 575 PRO 575 575 575 PRO PRO A . n 
A 1 576 SER 576 576 576 SER SER A . n 
A 1 577 LEU 577 577 577 LEU LEU A . n 
A 1 578 TYR 578 578 578 TYR TYR A . n 
A 1 579 ASP 579 579 579 ASP ASP A . n 
A 1 580 SER 580 580 580 SER SER A . n 
A 1 581 ILE 581 581 581 ILE ILE A . n 
A 1 582 ILE 582 582 582 ILE ILE A . n 
A 1 583 GLN 583 583 583 GLN GLN A . n 
A 1 584 VAL 584 584 584 VAL VAL A . n 
A 1 585 LYS 585 585 585 LYS LYS A . n 
A 1 586 LYS 586 586 586 LYS LYS A . n 
A 1 587 LEU 587 587 587 LEU LEU A . n 
A 1 588 PRO 588 588 588 PRO PRO A . n 
A 1 589 TYR 589 589 589 TYR TYR A . n 
A 1 590 LEU 590 590 ?   ?   ?   A . n 
A 1 591 PRO 591 591 ?   ?   ?   A . n 
A 1 592 ASP 592 592 ?   ?   ?   A . n 
A 1 593 LEU 593 593 ?   ?   ?   A . n 
A 1 594 GLY 594 594 ?   ?   ?   A . n 
A 1 595 TRP 595 595 ?   ?   ?   A . n 
A 1 596 ASN 596 596 ?   ?   ?   A . n 
A 1 597 GLN 597 597 ?   ?   ?   A . n 
A 1 598 LEU 598 598 ?   ?   ?   A . n 
A 1 599 SER 599 599 ?   ?   ?   A . n 
A 1 600 LYS 600 600 ?   ?   ?   A . n 
A 1 601 TYR 601 601 ?   ?   ?   A . n 
A 1 602 THR 602 602 ?   ?   ?   A . n 
A 1 603 ILE 603 603 ?   ?   ?   A . n 
A 1 604 PHE 604 604 ?   ?   ?   A . n 
A 1 605 VAL 605 605 ?   ?   ?   A . n 
A 1 606 GLU 606 606 ?   ?   ?   A . n 
A 1 607 ASP 607 607 ?   ?   ?   A . n 
A 1 608 ILE 608 608 ?   ?   ?   A . n 
A 1 609 MET 609 609 ?   ?   ?   A . n 
A 1 610 VAL 610 610 ?   ?   ?   A . n 
A 1 611 ARG 611 611 ?   ?   ?   A . n 
A 1 612 ASP 612 612 ?   ?   ?   A . n 
A 1 613 VAL 613 613 ?   ?   ?   A . n 
A 1 614 LYS 614 614 ?   ?   ?   A . n 
A 1 615 PHE 615 615 ?   ?   ?   A . n 
A 1 616 VAL 616 616 ?   ?   ?   A . n 
A 1 617 SER 617 617 ?   ?   ?   A . n 
A 1 618 ALA 618 618 ?   ?   ?   A . n 
A 1 619 SER 619 619 ?   ?   ?   A . n 
A 1 620 TYR 620 620 ?   ?   ?   A . n 
A 1 621 THR 621 621 ?   ?   ?   A . n 
A 1 622 TYR 622 622 ?   ?   ?   A . n 
A 1 623 GLY 623 623 ?   ?   ?   A . n 
A 1 624 GLU 624 624 ?   ?   ?   A . n 
A 1 625 LEU 625 625 ?   ?   ?   A . n 
A 1 626 ARG 626 626 ?   ?   ?   A . n 
A 1 627 THR 627 627 ?   ?   ?   A . n 
A 1 628 LEU 628 628 ?   ?   ?   A . n 
A 1 629 LEU 629 629 ?   ?   ?   A . n 
A 1 630 GLN 630 630 ?   ?   ?   A . n 
A 1 631 THR 631 631 ?   ?   ?   A . n 
A 1 632 THR 632 632 ?   ?   ?   A . n 
A 1 633 THR 633 633 ?   ?   ?   A . n 
A 1 634 VAL 634 634 ?   ?   ?   A . n 
A 1 635 LYS 635 635 ?   ?   ?   A . n 
A 1 636 THR 636 636 ?   ?   ?   A . n 
A 1 637 LEU 637 637 ?   ?   ?   A . n 
A 1 638 PRO 638 638 ?   ?   ?   A . n 
A 1 639 LEU 639 639 ?   ?   ?   A . n 
A 1 640 VAL 640 640 ?   ?   ?   A . n 
A 1 641 ASP 641 641 ?   ?   ?   A . n 
A 1 642 SER 642 642 ?   ?   ?   A . n 
A 1 643 LYS 643 643 ?   ?   ?   A . n 
A 1 644 ASP 644 644 ?   ?   ?   A . n 
A 1 645 SER 645 645 ?   ?   ?   A . n 
A 1 646 MET 646 646 ?   ?   ?   A . n 
A 1 647 ILE 647 647 ?   ?   ?   A . n 
A 1 648 LEU 648 648 ?   ?   ?   A . n 
A 1 649 LEU 649 649 ?   ?   ?   A . n 
A 1 650 GLY 650 650 ?   ?   ?   A . n 
A 1 651 SER 651 651 ?   ?   ?   A . n 
A 1 652 VAL 652 652 ?   ?   ?   A . n 
A 1 653 GLU 653 653 ?   ?   ?   A . n 
A 1 654 ARG 654 654 ?   ?   ?   A . n 
A 1 655 SER 655 655 ?   ?   ?   A . n 
A 1 656 GLU 656 656 ?   ?   ?   A . n 
A 1 657 LEU 657 657 ?   ?   ?   A . n 
A 1 658 GLN 658 658 ?   ?   ?   A . n 
A 1 659 ALA 659 659 ?   ?   ?   A . n 
A 1 660 LEU 660 660 ?   ?   ?   A . n 
A 1 661 LEU 661 661 ?   ?   ?   A . n 
A 1 662 GLN 662 662 ?   ?   ?   A . n 
A 1 663 ARG 663 663 ?   ?   ?   A . n 
A 1 664 HIS 664 664 ?   ?   ?   A . n 
A 1 665 LEU 665 665 ?   ?   ?   A . n 
A 1 666 CYS 666 666 ?   ?   ?   A . n 
A 1 667 PRO 667 667 ?   ?   ?   A . n 
A 1 668 GLU 668 668 ?   ?   ?   A . n 
A 1 669 ARG 669 669 ?   ?   ?   A . n 
A 1 670 ARG 670 670 ?   ?   ?   A . n 
A 1 671 LEU 671 671 ?   ?   ?   A . n 
A 1 672 ARG 672 672 ?   ?   ?   A . n 
A 1 673 ALA 673 673 ?   ?   ?   A . n 
A 1 674 ALA 674 674 ?   ?   ?   A . n 
A 1 675 GLN 675 675 ?   ?   ?   A . n 
A 1 676 GLU 676 676 ?   ?   ?   A . n 
A 1 677 MET 677 677 ?   ?   ?   A . n 
A 1 678 ALA 678 678 ?   ?   ?   A . n 
A 1 679 ARG 679 679 ?   ?   ?   A . n 
A 1 680 LYS 680 680 ?   ?   ?   A . n 
A 1 681 LEU 681 681 ?   ?   ?   A . n 
A 1 682 SER 682 682 ?   ?   ?   A . n 
A 1 683 GLU 683 683 ?   ?   ?   A . n 
A 1 684 LEU 684 684 ?   ?   ?   A . n 
A 1 685 PRO 685 685 ?   ?   ?   A . n 
A 1 686 TYR 686 686 ?   ?   ?   A . n 
A 1 687 ASP 687 687 ?   ?   ?   A . n 
A 1 688 GLY 688 688 ?   ?   ?   A . n 
A 1 689 LYS 689 689 ?   ?   ?   A . n 
A 1 690 ALA 690 690 ?   ?   ?   A . n 
A 1 691 ARG 691 691 ?   ?   ?   A . n 
A 1 692 LEU 692 692 ?   ?   ?   A . n 
A 1 693 ALA 693 693 ?   ?   ?   A . n 
A 1 694 GLY 694 694 ?   ?   ?   A . n 
A 1 695 GLU 695 695 ?   ?   ?   A . n 
A 1 696 GLY 696 696 ?   ?   ?   A . n 
A 1 697 LEU 697 697 ?   ?   ?   A . n 
A 1 698 PRO 698 698 ?   ?   ?   A . n 
A 1 699 GLY 699 699 ?   ?   ?   A . n 
A 1 700 ALA 700 700 ?   ?   ?   A . n 
A 1 701 PRO 701 701 ?   ?   ?   A . n 
A 1 702 PRO 702 702 ?   ?   ?   A . n 
A 1 703 GLY 703 703 ?   ?   ?   A . n 
A 1 704 ARG 704 704 ?   ?   ?   A . n 
A 1 705 PRO 705 705 ?   ?   ?   A . n 
A 1 706 GLU 706 706 ?   ?   ?   A . n 
A 1 707 SER 707 707 ?   ?   ?   A . n 
A 1 708 PHE 708 708 ?   ?   ?   A . n 
A 1 709 ALA 709 709 ?   ?   ?   A . n 
A 1 710 PHE 710 710 ?   ?   ?   A . n 
A 1 711 VAL 711 711 ?   ?   ?   A . n 
A 1 712 ASP 712 712 ?   ?   ?   A . n 
A 1 713 GLU 713 713 ?   ?   ?   A . n 
A 1 714 ASP 714 714 ?   ?   ?   A . n 
A 1 715 GLU 715 715 ?   ?   ?   A . n 
A 1 716 ASP 716 716 ?   ?   ?   A . n 
A 1 717 GLU 717 717 ?   ?   ?   A . n 
A 1 718 ASP 718 718 ?   ?   ?   A . n 
A 1 719 LEU 719 719 ?   ?   ?   A . n 
A 1 720 SER 720 720 ?   ?   ?   A . n 
A 1 721 GLY 721 721 ?   ?   ?   A . n 
A 1 722 LYS 722 722 ?   ?   ?   A . n 
A 1 723 SER 723 723 ?   ?   ?   A . n 
A 1 724 GLU 724 724 ?   ?   ?   A . n 
A 1 725 LEU 725 725 ?   ?   ?   A . n 
A 1 726 PRO 726 726 ?   ?   ?   A . n 
A 1 727 PRO 727 727 ?   ?   ?   A . n 
A 1 728 SER 728 728 ?   ?   ?   A . n 
A 1 729 LEU 729 729 ?   ?   ?   A . n 
A 1 730 ALA 730 730 ?   ?   ?   A . n 
A 1 731 LEU 731 731 ?   ?   ?   A . n 
A 1 732 HIS 732 732 ?   ?   ?   A . n 
A 1 733 PRO 733 733 ?   ?   ?   A . n 
A 1 734 SER 734 734 ?   ?   ?   A . n 
A 1 735 THR 735 735 ?   ?   ?   A . n 
A 1 736 THR 736 736 ?   ?   ?   A . n 
A 1 737 ALA 737 737 ?   ?   ?   A . n 
A 1 738 PRO 738 738 ?   ?   ?   A . n 
A 1 739 LEU 739 739 ?   ?   ?   A . n 
A 1 740 SER 740 740 ?   ?   ?   A . n 
A 1 741 PRO 741 741 ?   ?   ?   A . n 
A 1 742 GLU 742 742 ?   ?   ?   A . n 
A 1 743 GLU 743 743 ?   ?   ?   A . n 
A 1 744 PRO 744 744 ?   ?   ?   A . n 
A 1 745 ASN 745 745 ?   ?   ?   A . n 
A 1 746 GLY 746 746 ?   ?   ?   A . n 
A 1 747 PRO 747 747 ?   ?   ?   A . n 
A 1 748 LEU 748 748 ?   ?   ?   A . n 
A 1 749 PRO 749 749 ?   ?   ?   A . n 
A 1 750 GLY 750 750 ?   ?   ?   A . n 
A 1 751 HIS 751 751 ?   ?   ?   A . n 
A 1 752 LYS 752 752 ?   ?   ?   A . n 
A 1 753 GLN 753 753 ?   ?   ?   A . n 
A 1 754 GLN 754 754 ?   ?   ?   A . n 
A 1 755 PRO 755 755 ?   ?   ?   A . n 
A 1 756 GLU 756 756 ?   ?   ?   A . n 
A 1 757 ALA 757 757 ?   ?   ?   A . n 
A 1 758 PRO 758 758 ?   ?   ?   A . n 
A 1 759 GLU 759 759 ?   ?   ?   A . n 
A 1 760 PRO 760 760 ?   ?   ?   A . n 
A 1 761 ALA 761 761 ?   ?   ?   A . n 
A 1 762 GLY 762 762 ?   ?   ?   A . n 
A 1 763 GLN 763 763 ?   ?   ?   A . n 
A 1 764 ARG 764 764 ?   ?   ?   A . n 
A 1 765 PRO 765 765 ?   ?   ?   A . n 
A 1 766 SER 766 766 ?   ?   ?   A . n 
A 1 767 ILE 767 767 ?   ?   ?   A . n 
A 1 768 PHE 768 768 ?   ?   ?   A . n 
A 1 769 GLN 769 769 ?   ?   ?   A . n 
A 1 770 SER 770 770 ?   ?   ?   A . n 
A 1 771 LEU 771 771 ?   ?   ?   A . n 
A 1 772 LEU 772 772 ?   ?   ?   A . n 
A 1 773 HIS 773 773 ?   ?   ?   A . n 
A 1 774 CYS 774 774 ?   ?   ?   A . n 
A 1 775 LEU 775 775 ?   ?   ?   A . n 
A 1 776 LEU 776 776 ?   ?   ?   A . n 
A 1 777 GLY 777 777 ?   ?   ?   A . n 
A 1 778 ARG 778 778 ?   ?   ?   A . n 
A 1 779 ALA 779 779 ?   ?   ?   A . n 
A 1 780 ARG 780 780 ?   ?   ?   A . n 
A 1 781 PRO 781 781 ?   ?   ?   A . n 
A 1 782 THR 782 782 ?   ?   ?   A . n 
A 1 783 LYS 783 783 ?   ?   ?   A . n 
A 1 784 LYS 784 784 ?   ?   ?   A . n 
A 1 785 LYS 785 785 ?   ?   ?   A . n 
A 1 786 THR 786 786 ?   ?   ?   A . n 
A 1 787 THR 787 787 ?   ?   ?   A . n 
A 1 788 GLN 788 788 ?   ?   ?   A . n 
A 1 789 ASP 789 789 ?   ?   ?   A . n 
A 1 790 SER 790 790 ?   ?   ?   A . n 
A 1 791 THR 791 791 ?   ?   ?   A . n 
A 1 792 ASP 792 792 ?   ?   ?   A . n 
A 1 793 LEU 793 793 ?   ?   ?   A . n 
A 1 794 VAL 794 794 ?   ?   ?   A . n 
A 1 795 ASP 795 795 ?   ?   ?   A . n 
A 1 796 ASN 796 796 ?   ?   ?   A . n 
A 1 797 MET 797 797 ?   ?   ?   A . n 
A 1 798 SER 798 798 ?   ?   ?   A . n 
A 1 799 PRO 799 799 ?   ?   ?   A . n 
A 1 800 GLU 800 800 ?   ?   ?   A . n 
A 1 801 GLU 801 801 ?   ?   ?   A . n 
A 1 802 ILE 802 802 ?   ?   ?   A . n 
A 1 803 GLU 803 803 ?   ?   ?   A . n 
A 1 804 ALA 804 804 ?   ?   ?   A . n 
A 1 805 TRP 805 805 ?   ?   ?   A . n 
A 1 806 GLU 806 806 ?   ?   ?   A . n 
A 1 807 GLN 807 807 ?   ?   ?   A . n 
A 1 808 GLU 808 808 ?   ?   ?   A . n 
A 1 809 GLN 809 809 ?   ?   ?   A . n 
A 1 810 LEU 810 810 ?   ?   ?   A . n 
A 1 811 SER 811 811 ?   ?   ?   A . n 
A 1 812 GLN 812 812 ?   ?   ?   A . n 
A 1 813 PRO 813 813 ?   ?   ?   A . n 
A 1 814 VAL 814 814 ?   ?   ?   A . n 
A 1 815 CYS 815 815 ?   ?   ?   A . n 
A 1 816 PHE 816 816 ?   ?   ?   A . n 
A 1 817 ASP 817 817 ?   ?   ?   A . n 
A 1 818 SER 818 818 ?   ?   ?   A . n 
A 1 819 CYS 819 819 ?   ?   ?   A . n 
A 1 820 CYS 820 820 ?   ?   ?   A . n 
A 1 821 ILE 821 821 ?   ?   ?   A . n 
A 1 822 ASP 822 822 ?   ?   ?   A . n 
A 1 823 GLN 823 823 ?   ?   ?   A . n 
A 1 824 SER 824 824 ?   ?   ?   A . n 
A 1 825 PRO 825 825 ?   ?   ?   A . n 
A 1 826 PHE 826 826 ?   ?   ?   A . n 
A 1 827 GLN 827 827 ?   ?   ?   A . n 
A 1 828 LEU 828 828 ?   ?   ?   A . n 
A 1 829 VAL 829 829 ?   ?   ?   A . n 
A 1 830 GLU 830 830 ?   ?   ?   A . n 
A 1 831 GLN 831 831 ?   ?   ?   A . n 
A 1 832 THR 832 832 ?   ?   ?   A . n 
A 1 833 THR 833 833 ?   ?   ?   A . n 
A 1 834 LEU 834 834 ?   ?   ?   A . n 
A 1 835 HIS 835 835 ?   ?   ?   A . n 
A 1 836 LYS 836 836 ?   ?   ?   A . n 
A 1 837 THR 837 837 ?   ?   ?   A . n 
A 1 838 HIS 838 838 ?   ?   ?   A . n 
A 1 839 THR 839 839 ?   ?   ?   A . n 
A 1 840 LEU 840 840 ?   ?   ?   A . n 
A 1 841 PHE 841 841 ?   ?   ?   A . n 
A 1 842 SER 842 842 ?   ?   ?   A . n 
A 1 843 LEU 843 843 ?   ?   ?   A . n 
A 1 844 LEU 844 844 ?   ?   ?   A . n 
A 1 845 GLY 845 845 ?   ?   ?   A . n 
A 1 846 LEU 846 846 ?   ?   ?   A . n 
A 1 847 HIS 847 847 ?   ?   ?   A . n 
A 1 848 LEU 848 848 ?   ?   ?   A . n 
A 1 849 ALA 849 849 ?   ?   ?   A . n 
A 1 850 TYR 850 850 ?   ?   ?   A . n 
A 1 851 VAL 851 851 ?   ?   ?   A . n 
A 1 852 THR 852 852 ?   ?   ?   A . n 
A 1 853 SER 853 853 ?   ?   ?   A . n 
A 1 854 MET 854 854 ?   ?   ?   A . n 
A 1 855 GLY 855 855 ?   ?   ?   A . n 
A 1 856 LYS 856 856 ?   ?   ?   A . n 
A 1 857 LEU 857 857 ?   ?   ?   A . n 
A 1 858 ARG 858 858 ?   ?   ?   A . n 
A 1 859 GLY 859 859 ?   ?   ?   A . n 
A 1 860 VAL 860 860 ?   ?   ?   A . n 
A 1 861 LEU 861 861 ?   ?   ?   A . n 
A 1 862 ALA 862 862 ?   ?   ?   A . n 
A 1 863 LEU 863 863 ?   ?   ?   A . n 
A 1 864 GLU 864 864 ?   ?   ?   A . n 
A 1 865 GLU 865 865 ?   ?   ?   A . n 
A 1 866 LEU 866 866 ?   ?   ?   A . n 
A 1 867 GLN 867 867 ?   ?   ?   A . n 
A 1 868 LYS 868 868 ?   ?   ?   A . n 
A 1 869 ALA 869 869 ?   ?   ?   A . n 
A 1 870 ILE 870 870 ?   ?   ?   A . n 
A 1 871 GLU 871 871 ?   ?   ?   A . n 
A 1 872 GLY 872 872 ?   ?   ?   A . n 
A 1 873 HIS 873 873 ?   ?   ?   A . n 
A 1 874 THR 874 874 ?   ?   ?   A . n 
A 1 875 LYS 875 875 ?   ?   ?   A . n 
A 1 876 SER 876 876 ?   ?   ?   A . n 
A 1 877 GLY 877 877 ?   ?   ?   A . n 
A 1 878 VAL 878 878 ?   ?   ?   A . n 
A 1 879 GLN 879 879 ?   ?   ?   A . n 
A 1 880 LEU 880 880 ?   ?   ?   A . n 
A 1 881 ARG 881 881 ?   ?   ?   A . n 
A 1 882 PRO 882 882 ?   ?   ?   A . n 
A 1 883 PRO 883 883 ?   ?   ?   A . n 
A 1 884 LEU 884 884 ?   ?   ?   A . n 
A 1 885 ALA 885 885 ?   ?   ?   A . n 
A 1 886 SER 886 886 ?   ?   ?   A . n 
A 1 887 PHE 887 887 ?   ?   ?   A . n 
A 1 888 ARG 888 888 ?   ?   ?   A . n 
A 1 889 ASN 889 889 ?   ?   ?   A . n 
A 1 890 THR 890 890 ?   ?   ?   A . n 
A 1 891 THR 891 891 ?   ?   ?   A . n 
A 1 892 SER 892 892 ?   ?   ?   A . n 
A 1 893 THR 893 893 ?   ?   ?   A . n 
A 1 894 ARG 894 894 ?   ?   ?   A . n 
A 1 895 LYS 895 895 ?   ?   ?   A . n 
A 1 896 SER 896 896 ?   ?   ?   A . n 
A 1 897 THR 897 897 ?   ?   ?   A . n 
A 1 898 GLY 898 898 ?   ?   ?   A . n 
A 1 899 ALA 899 899 ?   ?   ?   A . n 
A 1 900 PRO 900 900 ?   ?   ?   A . n 
A 1 901 PRO 901 901 ?   ?   ?   A . n 
A 1 902 SER 902 902 ?   ?   ?   A . n 
A 1 903 SER 903 903 ?   ?   ?   A . n 
A 1 904 ALA 904 904 ?   ?   ?   A . n 
A 1 905 GLU 905 905 ?   ?   ?   A . n 
A 1 906 ASN 906 906 ?   ?   ?   A . n 
A 1 907 TRP 907 907 ?   ?   ?   A . n 
A 1 908 ASN 908 908 ?   ?   ?   A . n 
A 1 909 LEU 909 909 ?   ?   ?   A . n 
A 1 910 PRO 910 910 ?   ?   ?   A . n 
A 1 911 GLU 911 911 ?   ?   ?   A . n 
A 1 912 ASP 912 912 ?   ?   ?   A . n 
A 1 913 ARG 913 913 ?   ?   ?   A . n 
A 1 914 PRO 914 914 ?   ?   ?   A . n 
A 1 915 GLY 915 915 ?   ?   ?   A . n 
A 1 916 ALA 916 916 ?   ?   ?   A . n 
A 1 917 THR 917 917 ?   ?   ?   A . n 
A 1 918 GLY 918 918 ?   ?   ?   A . n 
A 1 919 THR 919 919 ?   ?   ?   A . n 
A 1 920 GLY 920 920 ?   ?   ?   A . n 
A 1 921 ASP 921 921 ?   ?   ?   A . n 
A 1 922 VAL 922 922 ?   ?   ?   A . n 
A 1 923 ILE 923 923 ?   ?   ?   A . n 
A 1 924 ALA 924 924 ?   ?   ?   A . n 
A 1 925 ALA 925 925 ?   ?   ?   A . n 
A 1 926 SER 926 926 ?   ?   ?   A . n 
A 1 927 PRO 927 927 ?   ?   ?   A . n 
A 1 928 GLU 928 928 ?   ?   ?   A . n 
A 1 929 THR 929 929 ?   ?   ?   A . n 
A 1 930 PRO 930 930 ?   ?   ?   A . n 
A 1 931 VAL 931 931 ?   ?   ?   A . n 
A 1 932 PRO 932 932 ?   ?   ?   A . n 
A 1 933 SER 933 933 ?   ?   ?   A . n 
A 1 934 PRO 934 934 ?   ?   ?   A . n 
A 1 935 SER 935 935 ?   ?   ?   A . n 
A 1 936 PRO 936 936 ?   ?   ?   A . n 
A 1 937 GLU 937 937 ?   ?   ?   A . n 
A 1 938 PRO 938 938 ?   ?   ?   A . n 
A 1 939 PRO 939 939 ?   ?   ?   A . n 
A 1 940 LEU 940 940 ?   ?   ?   A . n 
A 1 941 SER 941 941 ?   ?   ?   A . n 
A 1 942 LEU 942 942 ?   ?   ?   A . n 
A 1 943 ALA 943 943 ?   ?   ?   A . n 
A 1 944 PRO 944 944 ?   ?   ?   A . n 
A 1 945 GLY 945 945 ?   ?   ?   A . n 
A 1 946 LYS 946 946 ?   ?   ?   A . n 
A 1 947 VAL 947 947 ?   ?   ?   A . n 
A 1 948 GLU 948 948 ?   ?   ?   A . n 
A 1 949 GLY 949 949 ?   ?   ?   A . n 
A 1 950 GLU 950 950 ?   ?   ?   A . n 
A 1 951 LEU 951 951 ?   ?   ?   A . n 
A 1 952 GLU 952 952 ?   ?   ?   A . n 
A 1 953 GLU 953 953 ?   ?   ?   A . n 
A 1 954 LEU 954 954 ?   ?   ?   A . n 
A 1 955 GLU 955 955 ?   ?   ?   A . n 
A 1 956 LEU 956 956 ?   ?   ?   A . n 
A 1 957 VAL 957 957 ?   ?   ?   A . n 
A 1 958 GLU 958 958 ?   ?   ?   A . n 
A 1 959 SER 959 959 ?   ?   ?   A . n 
A 1 960 PRO 960 960 ?   ?   ?   A . n 
A 1 961 GLY 961 961 ?   ?   ?   A . n 
A 1 962 LEU 962 962 ?   ?   ?   A . n 
A 1 963 GLU 963 963 ?   ?   ?   A . n 
A 1 964 GLU 964 964 ?   ?   ?   A . n 
A 1 965 GLU 965 965 ?   ?   ?   A . n 
A 1 966 LEU 966 966 ?   ?   ?   A . n 
A 1 967 ALA 967 967 ?   ?   ?   A . n 
A 1 968 ASP 968 968 ?   ?   ?   A . n 
A 1 969 ILE 969 969 ?   ?   ?   A . n 
A 1 970 LEU 970 970 ?   ?   ?   A . n 
A 1 971 GLN 971 971 ?   ?   ?   A . n 
A 1 972 GLY 972 972 ?   ?   ?   A . n 
A 1 973 PRO 973 973 ?   ?   ?   A . n 
A 1 974 SER 974 974 ?   ?   ?   A . n 
A 1 975 LEU 975 975 ?   ?   ?   A . n 
A 1 976 ARG 976 976 ?   ?   ?   A . n 
A 1 977 SER 977 977 ?   ?   ?   A . n 
A 1 978 THR 978 978 ?   ?   ?   A . n 
A 1 979 ASP 979 979 ?   ?   ?   A . n 
A 1 980 GLU 980 980 ?   ?   ?   A . n 
A 1 981 GLU 981 981 ?   ?   ?   A . n 
A 1 982 ASP 982 982 ?   ?   ?   A . n 
A 1 983 GLU 983 983 ?   ?   ?   A . n 
A 1 984 ASP 984 984 ?   ?   ?   A . n 
A 1 985 GLU 985 985 ?   ?   ?   A . n 
A 1 986 LEU 986 986 ?   ?   ?   A . n 
A 1 987 ILE 987 987 ?   ?   ?   A . n 
A 1 988 LEU 988 988 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   GLU 2   2   ?   ?   ?   B . n 
B 1 3   GLN 3   3   ?   ?   ?   B . n 
B 1 4   SER 4   4   ?   ?   ?   B . n 
B 1 5   ARG 5   5   ?   ?   ?   B . n 
B 1 6   SER 6   6   ?   ?   ?   B . n 
B 1 7   GLN 7   7   ?   ?   ?   B . n 
B 1 8   GLN 8   8   ?   ?   ?   B . n 
B 1 9   ARG 9   9   ?   ?   ?   B . n 
B 1 10  GLY 10  10  ?   ?   ?   B . n 
B 1 11  GLY 11  11  ?   ?   ?   B . n 
B 1 12  GLU 12  12  ?   ?   ?   B . n 
B 1 13  GLN 13  13  ?   ?   ?   B . n 
B 1 14  SER 14  14  ?   ?   ?   B . n 
B 1 15  TRP 15  15  ?   ?   ?   B . n 
B 1 16  TRP 16  16  ?   ?   ?   B . n 
B 1 17  GLY 17  17  ?   ?   ?   B . n 
B 1 18  SER 18  18  ?   ?   ?   B . n 
B 1 19  ASP 19  19  ?   ?   ?   B . n 
B 1 20  PRO 20  20  ?   ?   ?   B . n 
B 1 21  GLN 21  21  ?   ?   ?   B . n 
B 1 22  TYR 22  22  ?   ?   ?   B . n 
B 1 23  GLN 23  23  ?   ?   ?   B . n 
B 1 24  TYR 24  24  ?   ?   ?   B . n 
B 1 25  MET 25  25  ?   ?   ?   B . n 
B 1 26  PRO 26  26  ?   ?   ?   B . n 
B 1 27  PHE 27  27  ?   ?   ?   B . n 
B 1 28  GLU 28  28  ?   ?   ?   B . n 
B 1 29  HIS 29  29  ?   ?   ?   B . n 
B 1 30  CYS 30  30  ?   ?   ?   B . n 
B 1 31  THR 31  31  ?   ?   ?   B . n 
B 1 32  SER 32  32  ?   ?   ?   B . n 
B 1 33  TYR 33  33  ?   ?   ?   B . n 
B 1 34  GLY 34  34  ?   ?   ?   B . n 
B 1 35  LEU 35  35  ?   ?   ?   B . n 
B 1 36  PRO 36  36  ?   ?   ?   B . n 
B 1 37  SER 37  37  ?   ?   ?   B . n 
B 1 38  GLU 38  38  ?   ?   ?   B . n 
B 1 39  ASN 39  39  ?   ?   ?   B . n 
B 1 40  GLY 40  40  ?   ?   ?   B . n 
B 1 41  GLY 41  41  ?   ?   ?   B . n 
B 1 42  LEU 42  42  ?   ?   ?   B . n 
B 1 43  GLN 43  43  ?   ?   ?   B . n 
B 1 44  HIS 44  44  ?   ?   ?   B . n 
B 1 45  ARG 45  45  ?   ?   ?   B . n 
B 1 46  LEU 46  46  ?   ?   ?   B . n 
B 1 47  ARG 47  47  ?   ?   ?   B . n 
B 1 48  LYS 48  48  ?   ?   ?   B . n 
B 1 49  ASP 49  49  ?   ?   ?   B . n 
B 1 50  ALA 50  50  ?   ?   ?   B . n 
B 1 51  GLY 51  51  ?   ?   ?   B . n 
B 1 52  PRO 52  52  ?   ?   ?   B . n 
B 1 53  ARG 53  53  ?   ?   ?   B . n 
B 1 54  HIS 54  54  ?   ?   ?   B . n 
B 1 55  ASN 55  55  ?   ?   ?   B . n 
B 1 56  VAL 56  56  ?   ?   ?   B . n 
B 1 57  HIS 57  57  ?   ?   ?   B . n 
B 1 58  PRO 58  58  ?   ?   ?   B . n 
B 1 59  THR 59  59  ?   ?   ?   B . n 
B 1 60  GLN 60  60  ?   ?   ?   B . n 
B 1 61  ILE 61  61  ?   ?   ?   B . n 
B 1 62  TYR 62  62  ?   ?   ?   B . n 
B 1 63  GLY 63  63  ?   ?   ?   B . n 
B 1 64  HIS 64  64  ?   ?   ?   B . n 
B 1 65  HIS 65  65  ?   ?   ?   B . n 
B 1 66  LYS 66  66  ?   ?   ?   B . n 
B 1 67  GLU 67  67  ?   ?   ?   B . n 
B 1 68  GLN 68  68  ?   ?   ?   B . n 
B 1 69  PHE 69  69  ?   ?   ?   B . n 
B 1 70  SER 70  70  ?   ?   ?   B . n 
B 1 71  ASP 71  71  ?   ?   ?   B . n 
B 1 72  ARG 72  72  ?   ?   ?   B . n 
B 1 73  GLU 73  73  ?   ?   ?   B . n 
B 1 74  GLN 74  74  ?   ?   ?   B . n 
B 1 75  ASP 75  75  ?   ?   ?   B . n 
B 1 76  ILE 76  76  ?   ?   ?   B . n 
B 1 77  GLY 77  77  ?   ?   ?   B . n 
B 1 78  MET 78  78  ?   ?   ?   B . n 
B 1 79  PRO 79  79  ?   ?   ?   B . n 
B 1 80  LYS 80  80  ?   ?   ?   B . n 
B 1 81  LYS 81  81  ?   ?   ?   B . n 
B 1 82  THR 82  82  ?   ?   ?   B . n 
B 1 83  GLY 83  83  ?   ?   ?   B . n 
B 1 84  SER 84  84  ?   ?   ?   B . n 
B 1 85  SER 85  85  ?   ?   ?   B . n 
B 1 86  SER 86  86  ?   ?   ?   B . n 
B 1 87  THR 87  87  ?   ?   ?   B . n 
B 1 88  VAL 88  88  ?   ?   ?   B . n 
B 1 89  ASP 89  89  ?   ?   ?   B . n 
B 1 90  SER 90  90  ?   ?   ?   B . n 
B 1 91  LYS 91  91  ?   ?   ?   B . n 
B 1 92  ASP 92  92  ?   ?   ?   B . n 
B 1 93  GLU 93  93  ?   ?   ?   B . n 
B 1 94  ASP 94  94  ?   ?   ?   B . n 
B 1 95  HIS 95  95  ?   ?   ?   B . n 
B 1 96  TYR 96  96  ?   ?   ?   B . n 
B 1 97  SER 97  97  ?   ?   ?   B . n 
B 1 98  LYS 98  98  ?   ?   ?   B . n 
B 1 99  CYS 99  99  ?   ?   ?   B . n 
B 1 100 GLN 100 100 ?   ?   ?   B . n 
B 1 101 ASP 101 101 ?   ?   ?   B . n 
B 1 102 CYS 102 102 ?   ?   ?   B . n 
B 1 103 ILE 103 103 ?   ?   ?   B . n 
B 1 104 HIS 104 104 ?   ?   ?   B . n 
B 1 105 ARG 105 105 ?   ?   ?   B . n 
B 1 106 LEU 106 106 ?   ?   ?   B . n 
B 1 107 GLY 107 107 ?   ?   ?   B . n 
B 1 108 GLN 108 108 ?   ?   ?   B . n 
B 1 109 VAL 109 109 ?   ?   ?   B . n 
B 1 110 VAL 110 110 ?   ?   ?   B . n 
B 1 111 ARG 111 111 ?   ?   ?   B . n 
B 1 112 ARG 112 112 ?   ?   ?   B . n 
B 1 113 LYS 113 113 ?   ?   ?   B . n 
B 1 114 LEU 114 114 ?   ?   ?   B . n 
B 1 115 GLY 115 115 115 GLY GLY B . n 
B 1 116 GLU 116 116 116 GLU GLU B . n 
B 1 117 ASP 117 117 117 ASP ASP B . n 
B 1 118 GLY 118 118 118 GLY GLY B . n 
B 1 119 ILE 119 119 119 ILE ILE B . n 
B 1 120 PHE 120 120 120 PHE PHE B . n 
B 1 121 LEU 121 121 121 LEU LEU B . n 
B 1 122 VAL 122 122 122 VAL VAL B . n 
B 1 123 LEU 123 123 123 LEU LEU B . n 
B 1 124 LEU 124 124 124 LEU LEU B . n 
B 1 125 GLY 125 125 125 GLY GLY B . n 
B 1 126 LEU 126 126 126 LEU LEU B . n 
B 1 127 LEU 127 127 127 LEU LEU B . n 
B 1 128 MET 128 128 128 MET MET B . n 
B 1 129 ALA 129 129 129 ALA ALA B . n 
B 1 130 LEU 130 130 130 LEU LEU B . n 
B 1 131 VAL 131 131 131 VAL VAL B . n 
B 1 132 SER 132 132 132 SER SER B . n 
B 1 133 TRP 133 133 133 TRP TRP B . n 
B 1 134 SER 134 134 134 SER SER B . n 
B 1 135 MET 135 135 135 MET MET B . n 
B 1 136 GLY 136 136 136 GLY GLY B . n 
B 1 137 TYR 137 137 137 TYR TYR B . n 
B 1 138 VAL 138 138 138 VAL VAL B . n 
B 1 139 SER 139 139 139 SER SER B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 LYS 141 141 141 LYS LYS B . n 
B 1 142 SER 142 142 142 SER SER B . n 
B 1 143 LEU 143 143 143 LEU LEU B . n 
B 1 144 GLN 144 144 144 GLN GLN B . n 
B 1 145 ALA 145 145 145 ALA ALA B . n 
B 1 146 TYR 146 146 146 TYR TYR B . n 
B 1 147 LYS 147 147 147 LYS LYS B . n 
B 1 148 TRP 148 148 148 TRP TRP B . n 
B 1 149 SER 149 149 149 SER SER B . n 
B 1 150 TYR 150 150 150 TYR TYR B . n 
B 1 151 ALA 151 151 151 ALA ALA B . n 
B 1 152 GLN 152 152 152 GLN GLN B . n 
B 1 153 MET 153 153 153 MET MET B . n 
B 1 154 GLN 154 154 154 GLN GLN B . n 
B 1 155 PRO 155 155 155 PRO PRO B . n 
B 1 156 SER 156 156 156 SER SER B . n 
B 1 157 LEU 157 157 157 LEU LEU B . n 
B 1 158 PRO 158 158 158 PRO PRO B . n 
B 1 159 LEU 159 159 159 LEU LEU B . n 
B 1 160 GLN 160 160 160 GLN GLN B . n 
B 1 161 PHE 161 161 161 PHE PHE B . n 
B 1 162 LEU 162 162 162 LEU LEU B . n 
B 1 163 VAL 163 163 163 VAL VAL B . n 
B 1 164 TRP 164 164 164 TRP TRP B . n 
B 1 165 VAL 165 165 165 VAL VAL B . n 
B 1 166 THR 166 166 166 THR THR B . n 
B 1 167 PHE 167 167 167 PHE PHE B . n 
B 1 168 PRO 168 168 168 PRO PRO B . n 
B 1 169 LEU 169 169 169 LEU LEU B . n 
B 1 170 VAL 170 170 170 VAL VAL B . n 
B 1 171 LEU 171 171 171 LEU LEU B . n 
B 1 172 ILE 172 172 172 ILE ILE B . n 
B 1 173 LEU 173 173 173 LEU LEU B . n 
B 1 174 PHE 174 174 174 PHE PHE B . n 
B 1 175 SER 175 175 175 SER SER B . n 
B 1 176 ALA 176 176 176 ALA ALA B . n 
B 1 177 LEU 177 177 177 LEU LEU B . n 
B 1 178 PHE 178 178 178 PHE PHE B . n 
B 1 179 CYS 179 179 179 CYS CYS B . n 
B 1 180 HIS 180 180 180 HIS HIS B . n 
B 1 181 LEU 181 181 181 LEU LEU B . n 
B 1 182 ILE 182 182 182 ILE ILE B . n 
B 1 183 SER 183 183 183 SER SER B . n 
B 1 184 PRO 184 184 184 PRO PRO B . n 
B 1 185 GLN 185 185 185 GLN GLN B . n 
B 1 186 ALA 186 186 186 ALA ALA B . n 
B 1 187 VAL 187 187 187 VAL VAL B . n 
B 1 188 GLY 188 188 188 GLY GLY B . n 
B 1 189 SER 189 189 189 SER SER B . n 
B 1 190 GLY 190 190 190 GLY GLY B . n 
B 1 191 ILE 191 191 191 ILE ILE B . n 
B 1 192 PRO 192 192 192 PRO PRO B . n 
B 1 193 GLU 193 193 193 GLU GLU B . n 
B 1 194 MET 194 194 194 MET MET B . n 
B 1 195 LYS 195 195 195 LYS LYS B . n 
B 1 196 THR 196 196 196 THR THR B . n 
B 1 197 ILE 197 197 197 ILE ILE B . n 
B 1 198 LEU 198 198 198 LEU LEU B . n 
B 1 199 ARG 199 199 199 ARG ARG B . n 
B 1 200 GLY 200 200 200 GLY GLY B . n 
B 1 201 VAL 201 201 201 VAL VAL B . n 
B 1 202 VAL 202 202 202 VAL VAL B . n 
B 1 203 LEU 203 203 203 LEU LEU B . n 
B 1 204 LYS 204 204 204 LYS LYS B . n 
B 1 205 GLU 205 205 205 GLU GLU B . n 
B 1 206 TYR 206 206 206 TYR TYR B . n 
B 1 207 LEU 207 207 207 LEU LEU B . n 
B 1 208 THR 208 208 208 THR THR B . n 
B 1 209 MET 209 209 209 MET MET B . n 
B 1 210 LYS 210 210 210 LYS LYS B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 PHE 212 212 212 PHE PHE B . n 
B 1 213 VAL 213 213 213 VAL VAL B . n 
B 1 214 ALA 214 214 214 ALA ALA B . n 
B 1 215 LYS 215 215 215 LYS LYS B . n 
B 1 216 VAL 216 216 216 VAL VAL B . n 
B 1 217 VAL 217 217 217 VAL VAL B . n 
B 1 218 ALA 218 218 218 ALA ALA B . n 
B 1 219 LEU 219 219 219 LEU LEU B . n 
B 1 220 THR 220 220 220 THR THR B . n 
B 1 221 ALA 221 221 221 ALA ALA B . n 
B 1 222 GLY 222 222 222 GLY GLY B . n 
B 1 223 LEU 223 223 223 LEU LEU B . n 
B 1 224 GLY 224 224 224 GLY GLY B . n 
B 1 225 SER 225 225 225 SER SER B . n 
B 1 226 GLY 226 226 226 GLY GLY B . n 
B 1 227 ILE 227 227 227 ILE ILE B . n 
B 1 228 PRO 228 228 228 PRO PRO B . n 
B 1 229 VAL 229 229 229 VAL VAL B . n 
B 1 230 GLY 230 230 230 GLY GLY B . n 
B 1 231 LYS 231 231 231 LYS LYS B . n 
B 1 232 GLU 232 232 232 GLU GLU B . n 
B 1 233 GLY 233 233 233 GLY GLY B . n 
B 1 234 PRO 234 234 234 PRO PRO B . n 
B 1 235 PHE 235 235 235 PHE PHE B . n 
B 1 236 VAL 236 236 236 VAL VAL B . n 
B 1 237 HIS 237 237 237 HIS HIS B . n 
B 1 238 ILE 238 238 238 ILE ILE B . n 
B 1 239 ALA 239 239 239 ALA ALA B . n 
B 1 240 SER 240 240 240 SER SER B . n 
B 1 241 ILE 241 241 241 ILE ILE B . n 
B 1 242 CYS 242 242 242 CYS CYS B . n 
B 1 243 ALA 243 243 243 ALA ALA B . n 
B 1 244 ALA 244 244 244 ALA ALA B . n 
B 1 245 VAL 245 245 245 VAL VAL B . n 
B 1 246 LEU 246 246 246 LEU LEU B . n 
B 1 247 SER 247 247 247 SER SER B . n 
B 1 248 LYS 248 248 248 LYS LYS B . n 
B 1 249 PHE 249 249 249 PHE PHE B . n 
B 1 250 MET 250 250 250 MET MET B . n 
B 1 251 SER 251 251 251 SER SER B . n 
B 1 252 VAL 252 252 252 VAL VAL B . n 
B 1 253 PHE 253 253 253 PHE PHE B . n 
B 1 254 CYS 254 254 ?   ?   ?   B . n 
B 1 255 GLY 255 255 ?   ?   ?   B . n 
B 1 256 VAL 256 256 ?   ?   ?   B . n 
B 1 257 TYR 257 257 ?   ?   ?   B . n 
B 1 258 GLU 258 258 ?   ?   ?   B . n 
B 1 259 GLN 259 259 ?   ?   ?   B . n 
B 1 260 PRO 260 260 ?   ?   ?   B . n 
B 1 261 TYR 261 261 ?   ?   ?   B . n 
B 1 262 TYR 262 262 262 TYR TYR B . n 
B 1 263 TYR 263 263 263 TYR TYR B . n 
B 1 264 SER 264 264 264 SER SER B . n 
B 1 265 ASP 265 265 265 ASP ASP B . n 
B 1 266 ILE 266 266 266 ILE ILE B . n 
B 1 267 LEU 267 267 267 LEU LEU B . n 
B 1 268 THR 268 268 268 THR THR B . n 
B 1 269 VAL 269 269 269 VAL VAL B . n 
B 1 270 GLY 270 270 270 GLY GLY B . n 
B 1 271 CYS 271 271 271 CYS CYS B . n 
B 1 272 ALA 272 272 272 ALA ALA B . n 
B 1 273 VAL 273 273 273 VAL VAL B . n 
B 1 274 GLY 274 274 274 GLY GLY B . n 
B 1 275 VAL 275 275 275 VAL VAL B . n 
B 1 276 GLY 276 276 276 GLY GLY B . n 
B 1 277 CYS 277 277 277 CYS CYS B . n 
B 1 278 CYS 278 278 278 CYS CYS B . n 
B 1 279 PHE 279 279 279 PHE PHE B . n 
B 1 280 GLY 280 280 280 GLY GLY B . n 
B 1 281 THR 281 281 281 THR THR B . n 
B 1 282 PRO 282 282 282 PRO PRO B . n 
B 1 283 LEU 283 283 283 LEU LEU B . n 
B 1 284 GLY 284 284 284 GLY GLY B . n 
B 1 285 GLY 285 285 285 GLY GLY B . n 
B 1 286 VAL 286 286 286 VAL VAL B . n 
B 1 287 LEU 287 287 287 LEU LEU B . n 
B 1 288 PHE 288 288 288 PHE PHE B . n 
B 1 289 SER 289 289 289 SER SER B . n 
B 1 290 ILE 290 290 290 ILE ILE B . n 
B 1 291 GLU 291 291 291 GLU GLU B . n 
B 1 292 VAL 292 292 292 VAL VAL B . n 
B 1 293 THR 293 293 293 THR THR B . n 
B 1 294 SER 294 294 294 SER SER B . n 
B 1 295 THR 295 295 295 THR THR B . n 
B 1 296 TYR 296 296 296 TYR TYR B . n 
B 1 297 PHE 297 297 297 PHE PHE B . n 
B 1 298 ALA 298 298 298 ALA ALA B . n 
B 1 299 VAL 299 299 299 VAL VAL B . n 
B 1 300 ARG 300 300 300 ARG ARG B . n 
B 1 301 ASN 301 301 301 ASN ASN B . n 
B 1 302 TYR 302 302 302 TYR TYR B . n 
B 1 303 TRP 303 303 303 TRP TRP B . n 
B 1 304 ARG 304 304 304 ARG ARG B . n 
B 1 305 GLY 305 305 305 GLY GLY B . n 
B 1 306 PHE 306 306 306 PHE PHE B . n 
B 1 307 PHE 307 307 307 PHE PHE B . n 
B 1 308 ALA 308 308 308 ALA ALA B . n 
B 1 309 ALA 309 309 309 ALA ALA B . n 
B 1 310 THR 310 310 310 THR THR B . n 
B 1 311 PHE 311 311 311 PHE PHE B . n 
B 1 312 SER 312 312 312 SER SER B . n 
B 1 313 ALA 313 313 313 ALA ALA B . n 
B 1 314 PHE 314 314 314 PHE PHE B . n 
B 1 315 VAL 315 315 315 VAL VAL B . n 
B 1 316 PHE 316 316 316 PHE PHE B . n 
B 1 317 ARG 317 317 317 ARG ARG B . n 
B 1 318 VAL 318 318 318 VAL VAL B . n 
B 1 319 LEU 319 319 319 LEU LEU B . n 
B 1 320 ALA 320 320 320 ALA ALA B . n 
B 1 321 VAL 321 321 321 VAL VAL B . n 
B 1 322 TRP 322 322 322 TRP TRP B . n 
B 1 323 ASN 323 323 323 ASN ASN B . n 
B 1 324 LYS 324 324 324 LYS LYS B . n 
B 1 325 ASP 325 325 325 ASP ASP B . n 
B 1 326 ALA 326 326 326 ALA ALA B . n 
B 1 327 VAL 327 327 327 VAL VAL B . n 
B 1 328 THR 328 328 328 THR THR B . n 
B 1 329 ILE 329 329 329 ILE ILE B . n 
B 1 330 THR 330 330 330 THR THR B . n 
B 1 331 ALA 331 331 331 ALA ALA B . n 
B 1 332 LEU 332 332 332 LEU LEU B . n 
B 1 333 PHE 333 333 333 PHE PHE B . n 
B 1 334 ARG 334 334 334 ARG ARG B . n 
B 1 335 THR 335 335 335 THR THR B . n 
B 1 336 ASN 336 336 336 ASN ASN B . n 
B 1 337 PHE 337 337 337 PHE PHE B . n 
B 1 338 ARG 338 338 338 ARG ARG B . n 
B 1 339 MET 339 339 339 MET MET B . n 
B 1 340 ASP 340 340 340 ASP ASP B . n 
B 1 341 PHE 341 341 341 PHE PHE B . n 
B 1 342 PRO 342 342 342 PRO PRO B . n 
B 1 343 PHE 343 343 343 PHE PHE B . n 
B 1 344 ASP 344 344 344 ASP ASP B . n 
B 1 345 LEU 345 345 345 LEU LEU B . n 
B 1 346 LYS 346 346 346 LYS LYS B . n 
B 1 347 GLU 347 347 347 GLU GLU B . n 
B 1 348 LEU 348 348 348 LEU LEU B . n 
B 1 349 PRO 349 349 349 PRO PRO B . n 
B 1 350 ALA 350 350 350 ALA ALA B . n 
B 1 351 PHE 351 351 351 PHE PHE B . n 
B 1 352 ALA 352 352 352 ALA ALA B . n 
B 1 353 ALA 353 353 353 ALA ALA B . n 
B 1 354 ILE 354 354 354 ILE ILE B . n 
B 1 355 GLY 355 355 355 GLY GLY B . n 
B 1 356 ILE 356 356 356 ILE ILE B . n 
B 1 357 CYS 357 357 357 CYS CYS B . n 
B 1 358 CYS 358 358 358 CYS CYS B . n 
B 1 359 GLY 359 359 359 GLY GLY B . n 
B 1 360 LEU 360 360 360 LEU LEU B . n 
B 1 361 LEU 361 361 361 LEU LEU B . n 
B 1 362 GLY 362 362 362 GLY GLY B . n 
B 1 363 ALA 363 363 363 ALA ALA B . n 
B 1 364 VAL 364 364 364 VAL VAL B . n 
B 1 365 PHE 365 365 365 PHE PHE B . n 
B 1 366 VAL 366 366 366 VAL VAL B . n 
B 1 367 TYR 367 367 367 TYR TYR B . n 
B 1 368 LEU 368 368 368 LEU LEU B . n 
B 1 369 HIS 369 369 369 HIS HIS B . n 
B 1 370 ARG 370 370 370 ARG ARG B . n 
B 1 371 GLN 371 371 371 GLN GLN B . n 
B 1 372 VAL 372 372 372 VAL VAL B . n 
B 1 373 MET 373 373 373 MET MET B . n 
B 1 374 LEU 374 374 374 LEU LEU B . n 
B 1 375 GLY 375 375 375 GLY GLY B . n 
B 1 376 VAL 376 376 376 VAL VAL B . n 
B 1 377 ARG 377 377 377 ARG ARG B . n 
B 1 378 LYS 378 378 378 LYS LYS B . n 
B 1 379 HIS 379 379 379 HIS HIS B . n 
B 1 380 LYS 380 380 380 LYS LYS B . n 
B 1 381 ALA 381 381 381 ALA ALA B . n 
B 1 382 LEU 382 382 382 LEU LEU B . n 
B 1 383 SER 383 383 383 SER SER B . n 
B 1 384 GLN 384 384 384 GLN GLN B . n 
B 1 385 PHE 385 385 385 PHE PHE B . n 
B 1 386 LEU 386 386 386 LEU LEU B . n 
B 1 387 ALA 387 387 387 ALA ALA B . n 
B 1 388 LYS 388 388 388 LYS LYS B . n 
B 1 389 HIS 389 389 389 HIS HIS B . n 
B 1 390 ARG 390 390 390 ARG ARG B . n 
B 1 391 LEU 391 391 391 LEU LEU B . n 
B 1 392 LEU 392 392 392 LEU LEU B . n 
B 1 393 TYR 393 393 393 TYR TYR B . n 
B 1 394 PRO 394 394 394 PRO PRO B . n 
B 1 395 GLY 395 395 395 GLY GLY B . n 
B 1 396 ILE 396 396 396 ILE ILE B . n 
B 1 397 VAL 397 397 397 VAL VAL B . n 
B 1 398 THR 398 398 398 THR THR B . n 
B 1 399 PHE 399 399 399 PHE PHE B . n 
B 1 400 VAL 400 400 400 VAL VAL B . n 
B 1 401 ILE 401 401 401 ILE ILE B . n 
B 1 402 ALA 402 402 402 ALA ALA B . n 
B 1 403 SER 403 403 403 SER SER B . n 
B 1 404 PHE 404 404 404 PHE PHE B . n 
B 1 405 THR 405 405 405 THR THR B . n 
B 1 406 PHE 406 406 406 PHE PHE B . n 
B 1 407 PRO 407 407 407 PRO PRO B . n 
B 1 408 PRO 408 408 408 PRO PRO B . n 
B 1 409 GLY 409 409 409 GLY GLY B . n 
B 1 410 MET 410 410 410 MET MET B . n 
B 1 411 GLY 411 411 411 GLY GLY B . n 
B 1 412 GLN 412 412 412 GLN GLN B . n 
B 1 413 PHE 413 413 413 PHE PHE B . n 
B 1 414 MET 414 414 414 MET MET B . n 
B 1 415 ALA 415 415 415 ALA ALA B . n 
B 1 416 GLY 416 416 416 GLY GLY B . n 
B 1 417 GLU 417 417 417 GLU GLU B . n 
B 1 418 LEU 418 418 418 LEU LEU B . n 
B 1 419 MET 419 419 419 MET MET B . n 
B 1 420 PRO 420 420 420 PRO PRO B . n 
B 1 421 ARG 421 421 421 ARG ARG B . n 
B 1 422 GLU 422 422 422 GLU GLU B . n 
B 1 423 ALA 423 423 423 ALA ALA B . n 
B 1 424 ILE 424 424 424 ILE ILE B . n 
B 1 425 SER 425 425 425 SER SER B . n 
B 1 426 THR 426 426 426 THR THR B . n 
B 1 427 LEU 427 427 427 LEU LEU B . n 
B 1 428 PHE 428 428 428 PHE PHE B . n 
B 1 429 ASP 429 429 429 ASP ASP B . n 
B 1 430 ASN 430 430 430 ASN ASN B . n 
B 1 431 ASN 431 431 431 ASN ASN B . n 
B 1 432 THR 432 432 432 THR THR B . n 
B 1 433 TRP 433 433 433 TRP TRP B . n 
B 1 434 VAL 434 434 434 VAL VAL B . n 
B 1 435 LYS 435 435 435 LYS LYS B . n 
B 1 436 HIS 436 436 436 HIS HIS B . n 
B 1 437 ALA 437 437 437 ALA ALA B . n 
B 1 438 GLY 438 438 438 GLY GLY B . n 
B 1 439 ASP 439 439 439 ASP ASP B . n 
B 1 440 PRO 440 440 440 PRO PRO B . n 
B 1 441 GLU 441 441 441 GLU GLU B . n 
B 1 442 SER 442 442 442 SER SER B . n 
B 1 443 LEU 443 443 443 LEU LEU B . n 
B 1 444 GLY 444 444 444 GLY GLY B . n 
B 1 445 GLN 445 445 445 GLN GLN B . n 
B 1 446 SER 446 446 446 SER SER B . n 
B 1 447 ALA 447 447 447 ALA ALA B . n 
B 1 448 VAL 448 448 448 VAL VAL B . n 
B 1 449 TRP 449 449 449 TRP TRP B . n 
B 1 450 ILE 450 450 450 ILE ILE B . n 
B 1 451 HIS 451 451 451 HIS HIS B . n 
B 1 452 PRO 452 452 452 PRO PRO B . n 
B 1 453 ARG 453 453 453 ARG ARG B . n 
B 1 454 VAL 454 454 454 VAL VAL B . n 
B 1 455 ASN 455 455 455 ASN ASN B . n 
B 1 456 VAL 456 456 456 VAL VAL B . n 
B 1 457 VAL 457 457 457 VAL VAL B . n 
B 1 458 ILE 458 458 458 ILE ILE B . n 
B 1 459 ILE 459 459 459 ILE ILE B . n 
B 1 460 ILE 460 460 460 ILE ILE B . n 
B 1 461 PHE 461 461 461 PHE PHE B . n 
B 1 462 LEU 462 462 462 LEU LEU B . n 
B 1 463 PHE 463 463 463 PHE PHE B . n 
B 1 464 PHE 464 464 464 PHE PHE B . n 
B 1 465 VAL 465 465 465 VAL VAL B . n 
B 1 466 MET 466 466 466 MET MET B . n 
B 1 467 LYS 467 467 467 LYS LYS B . n 
B 1 468 PHE 468 468 468 PHE PHE B . n 
B 1 469 TRP 469 469 469 TRP TRP B . n 
B 1 470 MET 470 470 470 MET MET B . n 
B 1 471 SER 471 471 471 SER SER B . n 
B 1 472 ILE 472 472 472 ILE ILE B . n 
B 1 473 VAL 473 473 473 VAL VAL B . n 
B 1 474 ALA 474 474 474 ALA ALA B . n 
B 1 475 THR 475 475 475 THR THR B . n 
B 1 476 THR 476 476 476 THR THR B . n 
B 1 477 MET 477 477 477 MET MET B . n 
B 1 478 PRO 478 478 478 PRO PRO B . n 
B 1 479 ILE 479 479 479 ILE ILE B . n 
B 1 480 PRO 480 480 480 PRO PRO B . n 
B 1 481 CYS 481 481 481 CYS CYS B . n 
B 1 482 GLY 482 482 482 GLY GLY B . n 
B 1 483 GLY 483 483 483 GLY GLY B . n 
B 1 484 PHE 484 484 484 PHE PHE B . n 
B 1 485 MET 485 485 485 MET MET B . n 
B 1 486 PRO 486 486 486 PRO PRO B . n 
B 1 487 VAL 487 487 487 VAL VAL B . n 
B 1 488 PHE 488 488 488 PHE PHE B . n 
B 1 489 VAL 489 489 489 VAL VAL B . n 
B 1 490 LEU 490 490 490 LEU LEU B . n 
B 1 491 GLY 491 491 491 GLY GLY B . n 
B 1 492 ALA 492 492 492 ALA ALA B . n 
B 1 493 ALA 493 493 493 ALA ALA B . n 
B 1 494 PHE 494 494 494 PHE PHE B . n 
B 1 495 GLY 495 495 495 GLY GLY B . n 
B 1 496 ARG 496 496 496 ARG ARG B . n 
B 1 497 LEU 497 497 497 LEU LEU B . n 
B 1 498 VAL 498 498 498 VAL VAL B . n 
B 1 499 GLY 499 499 499 GLY GLY B . n 
B 1 500 GLU 500 500 500 GLU GLU B . n 
B 1 501 ILE 501 501 501 ILE ILE B . n 
B 1 502 MET 502 502 502 MET MET B . n 
B 1 503 ALA 503 503 503 ALA ALA B . n 
B 1 504 MET 504 504 504 MET MET B . n 
B 1 505 LEU 505 505 505 LEU LEU B . n 
B 1 506 PHE 506 506 506 PHE PHE B . n 
B 1 507 PRO 507 507 507 PRO PRO B . n 
B 1 508 ASP 508 508 508 ASP ASP B . n 
B 1 509 GLY 509 509 509 GLY GLY B . n 
B 1 510 ILE 510 510 510 ILE ILE B . n 
B 1 511 LEU 511 511 511 LEU LEU B . n 
B 1 512 PHE 512 512 512 PHE PHE B . n 
B 1 513 ASP 513 513 513 ASP ASP B . n 
B 1 514 ASP 514 514 514 ASP ASP B . n 
B 1 515 ILE 515 515 515 ILE ILE B . n 
B 1 516 ILE 516 516 516 ILE ILE B . n 
B 1 517 TYR 517 517 517 TYR TYR B . n 
B 1 518 LYS 518 518 518 LYS LYS B . n 
B 1 519 ILE 519 519 519 ILE ILE B . n 
B 1 520 LEU 520 520 520 LEU LEU B . n 
B 1 521 PRO 521 521 521 PRO PRO B . n 
B 1 522 GLY 522 522 522 GLY GLY B . n 
B 1 523 GLY 523 523 523 GLY GLY B . n 
B 1 524 TYR 524 524 524 TYR TYR B . n 
B 1 525 ALA 525 525 525 ALA ALA B . n 
B 1 526 VAL 526 526 526 VAL VAL B . n 
B 1 527 ILE 527 527 527 ILE ILE B . n 
B 1 528 GLY 528 528 528 GLY GLY B . n 
B 1 529 ALA 529 529 529 ALA ALA B . n 
B 1 530 ALA 530 530 530 ALA ALA B . n 
B 1 531 ALA 531 531 531 ALA ALA B . n 
B 1 532 LEU 532 532 532 LEU LEU B . n 
B 1 533 THR 533 533 533 THR THR B . n 
B 1 534 GLY 534 534 534 GLY GLY B . n 
B 1 535 ALA 535 535 535 ALA ALA B . n 
B 1 536 VAL 536 536 536 VAL VAL B . n 
B 1 537 SER 537 537 537 SER SER B . n 
B 1 538 HIS 538 538 538 HIS HIS B . n 
B 1 539 THR 539 539 539 THR THR B . n 
B 1 540 VAL 540 540 540 VAL VAL B . n 
B 1 541 SER 541 541 541 SER SER B . n 
B 1 542 THR 542 542 542 THR THR B . n 
B 1 543 ALA 543 543 543 ALA ALA B . n 
B 1 544 VAL 544 544 544 VAL VAL B . n 
B 1 545 ILE 545 545 545 ILE ILE B . n 
B 1 546 CYS 546 546 546 CYS CYS B . n 
B 1 547 PHE 547 547 547 PHE PHE B . n 
B 1 548 GLU 548 548 548 GLU GLU B . n 
B 1 549 LEU 549 549 549 LEU LEU B . n 
B 1 550 THR 550 550 550 THR THR B . n 
B 1 551 GLY 551 551 551 GLY GLY B . n 
B 1 552 GLN 552 552 552 GLN GLN B . n 
B 1 553 ILE 553 553 553 ILE ILE B . n 
B 1 554 ALA 554 554 554 ALA ALA B . n 
B 1 555 HIS 555 555 555 HIS HIS B . n 
B 1 556 ILE 556 556 556 ILE ILE B . n 
B 1 557 LEU 557 557 557 LEU LEU B . n 
B 1 558 PRO 558 558 558 PRO PRO B . n 
B 1 559 MET 559 559 559 MET MET B . n 
B 1 560 MET 560 560 560 MET MET B . n 
B 1 561 VAL 561 561 561 VAL VAL B . n 
B 1 562 ALA 562 562 562 ALA ALA B . n 
B 1 563 VAL 563 563 563 VAL VAL B . n 
B 1 564 ILE 564 564 564 ILE ILE B . n 
B 1 565 LEU 565 565 565 LEU LEU B . n 
B 1 566 ALA 566 566 566 ALA ALA B . n 
B 1 567 ASN 567 567 567 ASN ASN B . n 
B 1 568 MET 568 568 568 MET MET B . n 
B 1 569 VAL 569 569 569 VAL VAL B . n 
B 1 570 ALA 570 570 570 ALA ALA B . n 
B 1 571 GLN 571 571 571 GLN GLN B . n 
B 1 572 SER 572 572 572 SER SER B . n 
B 1 573 LEU 573 573 573 LEU LEU B . n 
B 1 574 GLN 574 574 574 GLN GLN B . n 
B 1 575 PRO 575 575 575 PRO PRO B . n 
B 1 576 SER 576 576 576 SER SER B . n 
B 1 577 LEU 577 577 577 LEU LEU B . n 
B 1 578 TYR 578 578 578 TYR TYR B . n 
B 1 579 ASP 579 579 579 ASP ASP B . n 
B 1 580 SER 580 580 580 SER SER B . n 
B 1 581 ILE 581 581 581 ILE ILE B . n 
B 1 582 ILE 582 582 582 ILE ILE B . n 
B 1 583 GLN 583 583 583 GLN GLN B . n 
B 1 584 VAL 584 584 584 VAL VAL B . n 
B 1 585 LYS 585 585 585 LYS LYS B . n 
B 1 586 LYS 586 586 586 LYS LYS B . n 
B 1 587 LEU 587 587 587 LEU LEU B . n 
B 1 588 PRO 588 588 588 PRO PRO B . n 
B 1 589 TYR 589 589 589 TYR TYR B . n 
B 1 590 LEU 590 590 ?   ?   ?   B . n 
B 1 591 PRO 591 591 ?   ?   ?   B . n 
B 1 592 ASP 592 592 ?   ?   ?   B . n 
B 1 593 LEU 593 593 ?   ?   ?   B . n 
B 1 594 GLY 594 594 ?   ?   ?   B . n 
B 1 595 TRP 595 595 ?   ?   ?   B . n 
B 1 596 ASN 596 596 ?   ?   ?   B . n 
B 1 597 GLN 597 597 ?   ?   ?   B . n 
B 1 598 LEU 598 598 ?   ?   ?   B . n 
B 1 599 SER 599 599 ?   ?   ?   B . n 
B 1 600 LYS 600 600 ?   ?   ?   B . n 
B 1 601 TYR 601 601 ?   ?   ?   B . n 
B 1 602 THR 602 602 ?   ?   ?   B . n 
B 1 603 ILE 603 603 ?   ?   ?   B . n 
B 1 604 PHE 604 604 ?   ?   ?   B . n 
B 1 605 VAL 605 605 ?   ?   ?   B . n 
B 1 606 GLU 606 606 ?   ?   ?   B . n 
B 1 607 ASP 607 607 ?   ?   ?   B . n 
B 1 608 ILE 608 608 ?   ?   ?   B . n 
B 1 609 MET 609 609 ?   ?   ?   B . n 
B 1 610 VAL 610 610 ?   ?   ?   B . n 
B 1 611 ARG 611 611 ?   ?   ?   B . n 
B 1 612 ASP 612 612 ?   ?   ?   B . n 
B 1 613 VAL 613 613 ?   ?   ?   B . n 
B 1 614 LYS 614 614 ?   ?   ?   B . n 
B 1 615 PHE 615 615 ?   ?   ?   B . n 
B 1 616 VAL 616 616 ?   ?   ?   B . n 
B 1 617 SER 617 617 ?   ?   ?   B . n 
B 1 618 ALA 618 618 ?   ?   ?   B . n 
B 1 619 SER 619 619 ?   ?   ?   B . n 
B 1 620 TYR 620 620 ?   ?   ?   B . n 
B 1 621 THR 621 621 ?   ?   ?   B . n 
B 1 622 TYR 622 622 ?   ?   ?   B . n 
B 1 623 GLY 623 623 ?   ?   ?   B . n 
B 1 624 GLU 624 624 ?   ?   ?   B . n 
B 1 625 LEU 625 625 ?   ?   ?   B . n 
B 1 626 ARG 626 626 ?   ?   ?   B . n 
B 1 627 THR 627 627 ?   ?   ?   B . n 
B 1 628 LEU 628 628 ?   ?   ?   B . n 
B 1 629 LEU 629 629 ?   ?   ?   B . n 
B 1 630 GLN 630 630 ?   ?   ?   B . n 
B 1 631 THR 631 631 ?   ?   ?   B . n 
B 1 632 THR 632 632 ?   ?   ?   B . n 
B 1 633 THR 633 633 ?   ?   ?   B . n 
B 1 634 VAL 634 634 ?   ?   ?   B . n 
B 1 635 LYS 635 635 ?   ?   ?   B . n 
B 1 636 THR 636 636 ?   ?   ?   B . n 
B 1 637 LEU 637 637 ?   ?   ?   B . n 
B 1 638 PRO 638 638 ?   ?   ?   B . n 
B 1 639 LEU 639 639 ?   ?   ?   B . n 
B 1 640 VAL 640 640 ?   ?   ?   B . n 
B 1 641 ASP 641 641 ?   ?   ?   B . n 
B 1 642 SER 642 642 ?   ?   ?   B . n 
B 1 643 LYS 643 643 ?   ?   ?   B . n 
B 1 644 ASP 644 644 ?   ?   ?   B . n 
B 1 645 SER 645 645 ?   ?   ?   B . n 
B 1 646 MET 646 646 ?   ?   ?   B . n 
B 1 647 ILE 647 647 ?   ?   ?   B . n 
B 1 648 LEU 648 648 ?   ?   ?   B . n 
B 1 649 LEU 649 649 ?   ?   ?   B . n 
B 1 650 GLY 650 650 ?   ?   ?   B . n 
B 1 651 SER 651 651 ?   ?   ?   B . n 
B 1 652 VAL 652 652 ?   ?   ?   B . n 
B 1 653 GLU 653 653 ?   ?   ?   B . n 
B 1 654 ARG 654 654 ?   ?   ?   B . n 
B 1 655 SER 655 655 ?   ?   ?   B . n 
B 1 656 GLU 656 656 ?   ?   ?   B . n 
B 1 657 LEU 657 657 ?   ?   ?   B . n 
B 1 658 GLN 658 658 ?   ?   ?   B . n 
B 1 659 ALA 659 659 ?   ?   ?   B . n 
B 1 660 LEU 660 660 ?   ?   ?   B . n 
B 1 661 LEU 661 661 ?   ?   ?   B . n 
B 1 662 GLN 662 662 ?   ?   ?   B . n 
B 1 663 ARG 663 663 ?   ?   ?   B . n 
B 1 664 HIS 664 664 ?   ?   ?   B . n 
B 1 665 LEU 665 665 ?   ?   ?   B . n 
B 1 666 CYS 666 666 ?   ?   ?   B . n 
B 1 667 PRO 667 667 ?   ?   ?   B . n 
B 1 668 GLU 668 668 ?   ?   ?   B . n 
B 1 669 ARG 669 669 ?   ?   ?   B . n 
B 1 670 ARG 670 670 ?   ?   ?   B . n 
B 1 671 LEU 671 671 ?   ?   ?   B . n 
B 1 672 ARG 672 672 ?   ?   ?   B . n 
B 1 673 ALA 673 673 ?   ?   ?   B . n 
B 1 674 ALA 674 674 ?   ?   ?   B . n 
B 1 675 GLN 675 675 ?   ?   ?   B . n 
B 1 676 GLU 676 676 ?   ?   ?   B . n 
B 1 677 MET 677 677 ?   ?   ?   B . n 
B 1 678 ALA 678 678 ?   ?   ?   B . n 
B 1 679 ARG 679 679 ?   ?   ?   B . n 
B 1 680 LYS 680 680 ?   ?   ?   B . n 
B 1 681 LEU 681 681 ?   ?   ?   B . n 
B 1 682 SER 682 682 ?   ?   ?   B . n 
B 1 683 GLU 683 683 ?   ?   ?   B . n 
B 1 684 LEU 684 684 ?   ?   ?   B . n 
B 1 685 PRO 685 685 ?   ?   ?   B . n 
B 1 686 TYR 686 686 ?   ?   ?   B . n 
B 1 687 ASP 687 687 ?   ?   ?   B . n 
B 1 688 GLY 688 688 ?   ?   ?   B . n 
B 1 689 LYS 689 689 ?   ?   ?   B . n 
B 1 690 ALA 690 690 ?   ?   ?   B . n 
B 1 691 ARG 691 691 ?   ?   ?   B . n 
B 1 692 LEU 692 692 ?   ?   ?   B . n 
B 1 693 ALA 693 693 ?   ?   ?   B . n 
B 1 694 GLY 694 694 ?   ?   ?   B . n 
B 1 695 GLU 695 695 ?   ?   ?   B . n 
B 1 696 GLY 696 696 ?   ?   ?   B . n 
B 1 697 LEU 697 697 ?   ?   ?   B . n 
B 1 698 PRO 698 698 ?   ?   ?   B . n 
B 1 699 GLY 699 699 ?   ?   ?   B . n 
B 1 700 ALA 700 700 ?   ?   ?   B . n 
B 1 701 PRO 701 701 ?   ?   ?   B . n 
B 1 702 PRO 702 702 ?   ?   ?   B . n 
B 1 703 GLY 703 703 ?   ?   ?   B . n 
B 1 704 ARG 704 704 ?   ?   ?   B . n 
B 1 705 PRO 705 705 ?   ?   ?   B . n 
B 1 706 GLU 706 706 ?   ?   ?   B . n 
B 1 707 SER 707 707 ?   ?   ?   B . n 
B 1 708 PHE 708 708 ?   ?   ?   B . n 
B 1 709 ALA 709 709 ?   ?   ?   B . n 
B 1 710 PHE 710 710 ?   ?   ?   B . n 
B 1 711 VAL 711 711 ?   ?   ?   B . n 
B 1 712 ASP 712 712 ?   ?   ?   B . n 
B 1 713 GLU 713 713 ?   ?   ?   B . n 
B 1 714 ASP 714 714 ?   ?   ?   B . n 
B 1 715 GLU 715 715 ?   ?   ?   B . n 
B 1 716 ASP 716 716 ?   ?   ?   B . n 
B 1 717 GLU 717 717 ?   ?   ?   B . n 
B 1 718 ASP 718 718 ?   ?   ?   B . n 
B 1 719 LEU 719 719 ?   ?   ?   B . n 
B 1 720 SER 720 720 ?   ?   ?   B . n 
B 1 721 GLY 721 721 ?   ?   ?   B . n 
B 1 722 LYS 722 722 ?   ?   ?   B . n 
B 1 723 SER 723 723 ?   ?   ?   B . n 
B 1 724 GLU 724 724 ?   ?   ?   B . n 
B 1 725 LEU 725 725 ?   ?   ?   B . n 
B 1 726 PRO 726 726 ?   ?   ?   B . n 
B 1 727 PRO 727 727 ?   ?   ?   B . n 
B 1 728 SER 728 728 ?   ?   ?   B . n 
B 1 729 LEU 729 729 ?   ?   ?   B . n 
B 1 730 ALA 730 730 ?   ?   ?   B . n 
B 1 731 LEU 731 731 ?   ?   ?   B . n 
B 1 732 HIS 732 732 ?   ?   ?   B . n 
B 1 733 PRO 733 733 ?   ?   ?   B . n 
B 1 734 SER 734 734 ?   ?   ?   B . n 
B 1 735 THR 735 735 ?   ?   ?   B . n 
B 1 736 THR 736 736 ?   ?   ?   B . n 
B 1 737 ALA 737 737 ?   ?   ?   B . n 
B 1 738 PRO 738 738 ?   ?   ?   B . n 
B 1 739 LEU 739 739 ?   ?   ?   B . n 
B 1 740 SER 740 740 ?   ?   ?   B . n 
B 1 741 PRO 741 741 ?   ?   ?   B . n 
B 1 742 GLU 742 742 ?   ?   ?   B . n 
B 1 743 GLU 743 743 ?   ?   ?   B . n 
B 1 744 PRO 744 744 ?   ?   ?   B . n 
B 1 745 ASN 745 745 ?   ?   ?   B . n 
B 1 746 GLY 746 746 ?   ?   ?   B . n 
B 1 747 PRO 747 747 ?   ?   ?   B . n 
B 1 748 LEU 748 748 ?   ?   ?   B . n 
B 1 749 PRO 749 749 ?   ?   ?   B . n 
B 1 750 GLY 750 750 ?   ?   ?   B . n 
B 1 751 HIS 751 751 ?   ?   ?   B . n 
B 1 752 LYS 752 752 ?   ?   ?   B . n 
B 1 753 GLN 753 753 ?   ?   ?   B . n 
B 1 754 GLN 754 754 ?   ?   ?   B . n 
B 1 755 PRO 755 755 ?   ?   ?   B . n 
B 1 756 GLU 756 756 ?   ?   ?   B . n 
B 1 757 ALA 757 757 ?   ?   ?   B . n 
B 1 758 PRO 758 758 ?   ?   ?   B . n 
B 1 759 GLU 759 759 ?   ?   ?   B . n 
B 1 760 PRO 760 760 ?   ?   ?   B . n 
B 1 761 ALA 761 761 ?   ?   ?   B . n 
B 1 762 GLY 762 762 ?   ?   ?   B . n 
B 1 763 GLN 763 763 ?   ?   ?   B . n 
B 1 764 ARG 764 764 ?   ?   ?   B . n 
B 1 765 PRO 765 765 ?   ?   ?   B . n 
B 1 766 SER 766 766 ?   ?   ?   B . n 
B 1 767 ILE 767 767 ?   ?   ?   B . n 
B 1 768 PHE 768 768 ?   ?   ?   B . n 
B 1 769 GLN 769 769 ?   ?   ?   B . n 
B 1 770 SER 770 770 ?   ?   ?   B . n 
B 1 771 LEU 771 771 ?   ?   ?   B . n 
B 1 772 LEU 772 772 ?   ?   ?   B . n 
B 1 773 HIS 773 773 ?   ?   ?   B . n 
B 1 774 CYS 774 774 ?   ?   ?   B . n 
B 1 775 LEU 775 775 ?   ?   ?   B . n 
B 1 776 LEU 776 776 ?   ?   ?   B . n 
B 1 777 GLY 777 777 ?   ?   ?   B . n 
B 1 778 ARG 778 778 ?   ?   ?   B . n 
B 1 779 ALA 779 779 ?   ?   ?   B . n 
B 1 780 ARG 780 780 ?   ?   ?   B . n 
B 1 781 PRO 781 781 ?   ?   ?   B . n 
B 1 782 THR 782 782 ?   ?   ?   B . n 
B 1 783 LYS 783 783 ?   ?   ?   B . n 
B 1 784 LYS 784 784 ?   ?   ?   B . n 
B 1 785 LYS 785 785 ?   ?   ?   B . n 
B 1 786 THR 786 786 ?   ?   ?   B . n 
B 1 787 THR 787 787 ?   ?   ?   B . n 
B 1 788 GLN 788 788 ?   ?   ?   B . n 
B 1 789 ASP 789 789 ?   ?   ?   B . n 
B 1 790 SER 790 790 ?   ?   ?   B . n 
B 1 791 THR 791 791 ?   ?   ?   B . n 
B 1 792 ASP 792 792 ?   ?   ?   B . n 
B 1 793 LEU 793 793 ?   ?   ?   B . n 
B 1 794 VAL 794 794 ?   ?   ?   B . n 
B 1 795 ASP 795 795 ?   ?   ?   B . n 
B 1 796 ASN 796 796 ?   ?   ?   B . n 
B 1 797 MET 797 797 ?   ?   ?   B . n 
B 1 798 SER 798 798 ?   ?   ?   B . n 
B 1 799 PRO 799 799 ?   ?   ?   B . n 
B 1 800 GLU 800 800 ?   ?   ?   B . n 
B 1 801 GLU 801 801 ?   ?   ?   B . n 
B 1 802 ILE 802 802 ?   ?   ?   B . n 
B 1 803 GLU 803 803 ?   ?   ?   B . n 
B 1 804 ALA 804 804 ?   ?   ?   B . n 
B 1 805 TRP 805 805 ?   ?   ?   B . n 
B 1 806 GLU 806 806 ?   ?   ?   B . n 
B 1 807 GLN 807 807 ?   ?   ?   B . n 
B 1 808 GLU 808 808 ?   ?   ?   B . n 
B 1 809 GLN 809 809 ?   ?   ?   B . n 
B 1 810 LEU 810 810 ?   ?   ?   B . n 
B 1 811 SER 811 811 ?   ?   ?   B . n 
B 1 812 GLN 812 812 ?   ?   ?   B . n 
B 1 813 PRO 813 813 ?   ?   ?   B . n 
B 1 814 VAL 814 814 ?   ?   ?   B . n 
B 1 815 CYS 815 815 ?   ?   ?   B . n 
B 1 816 PHE 816 816 ?   ?   ?   B . n 
B 1 817 ASP 817 817 ?   ?   ?   B . n 
B 1 818 SER 818 818 ?   ?   ?   B . n 
B 1 819 CYS 819 819 ?   ?   ?   B . n 
B 1 820 CYS 820 820 ?   ?   ?   B . n 
B 1 821 ILE 821 821 ?   ?   ?   B . n 
B 1 822 ASP 822 822 ?   ?   ?   B . n 
B 1 823 GLN 823 823 ?   ?   ?   B . n 
B 1 824 SER 824 824 ?   ?   ?   B . n 
B 1 825 PRO 825 825 ?   ?   ?   B . n 
B 1 826 PHE 826 826 ?   ?   ?   B . n 
B 1 827 GLN 827 827 ?   ?   ?   B . n 
B 1 828 LEU 828 828 ?   ?   ?   B . n 
B 1 829 VAL 829 829 ?   ?   ?   B . n 
B 1 830 GLU 830 830 ?   ?   ?   B . n 
B 1 831 GLN 831 831 ?   ?   ?   B . n 
B 1 832 THR 832 832 ?   ?   ?   B . n 
B 1 833 THR 833 833 ?   ?   ?   B . n 
B 1 834 LEU 834 834 ?   ?   ?   B . n 
B 1 835 HIS 835 835 ?   ?   ?   B . n 
B 1 836 LYS 836 836 ?   ?   ?   B . n 
B 1 837 THR 837 837 ?   ?   ?   B . n 
B 1 838 HIS 838 838 ?   ?   ?   B . n 
B 1 839 THR 839 839 ?   ?   ?   B . n 
B 1 840 LEU 840 840 ?   ?   ?   B . n 
B 1 841 PHE 841 841 ?   ?   ?   B . n 
B 1 842 SER 842 842 ?   ?   ?   B . n 
B 1 843 LEU 843 843 ?   ?   ?   B . n 
B 1 844 LEU 844 844 ?   ?   ?   B . n 
B 1 845 GLY 845 845 ?   ?   ?   B . n 
B 1 846 LEU 846 846 ?   ?   ?   B . n 
B 1 847 HIS 847 847 ?   ?   ?   B . n 
B 1 848 LEU 848 848 ?   ?   ?   B . n 
B 1 849 ALA 849 849 ?   ?   ?   B . n 
B 1 850 TYR 850 850 ?   ?   ?   B . n 
B 1 851 VAL 851 851 ?   ?   ?   B . n 
B 1 852 THR 852 852 ?   ?   ?   B . n 
B 1 853 SER 853 853 ?   ?   ?   B . n 
B 1 854 MET 854 854 ?   ?   ?   B . n 
B 1 855 GLY 855 855 ?   ?   ?   B . n 
B 1 856 LYS 856 856 ?   ?   ?   B . n 
B 1 857 LEU 857 857 ?   ?   ?   B . n 
B 1 858 ARG 858 858 ?   ?   ?   B . n 
B 1 859 GLY 859 859 ?   ?   ?   B . n 
B 1 860 VAL 860 860 ?   ?   ?   B . n 
B 1 861 LEU 861 861 ?   ?   ?   B . n 
B 1 862 ALA 862 862 ?   ?   ?   B . n 
B 1 863 LEU 863 863 ?   ?   ?   B . n 
B 1 864 GLU 864 864 ?   ?   ?   B . n 
B 1 865 GLU 865 865 ?   ?   ?   B . n 
B 1 866 LEU 866 866 ?   ?   ?   B . n 
B 1 867 GLN 867 867 ?   ?   ?   B . n 
B 1 868 LYS 868 868 ?   ?   ?   B . n 
B 1 869 ALA 869 869 ?   ?   ?   B . n 
B 1 870 ILE 870 870 ?   ?   ?   B . n 
B 1 871 GLU 871 871 ?   ?   ?   B . n 
B 1 872 GLY 872 872 ?   ?   ?   B . n 
B 1 873 HIS 873 873 ?   ?   ?   B . n 
B 1 874 THR 874 874 ?   ?   ?   B . n 
B 1 875 LYS 875 875 ?   ?   ?   B . n 
B 1 876 SER 876 876 ?   ?   ?   B . n 
B 1 877 GLY 877 877 ?   ?   ?   B . n 
B 1 878 VAL 878 878 ?   ?   ?   B . n 
B 1 879 GLN 879 879 ?   ?   ?   B . n 
B 1 880 LEU 880 880 ?   ?   ?   B . n 
B 1 881 ARG 881 881 ?   ?   ?   B . n 
B 1 882 PRO 882 882 ?   ?   ?   B . n 
B 1 883 PRO 883 883 ?   ?   ?   B . n 
B 1 884 LEU 884 884 ?   ?   ?   B . n 
B 1 885 ALA 885 885 ?   ?   ?   B . n 
B 1 886 SER 886 886 ?   ?   ?   B . n 
B 1 887 PHE 887 887 ?   ?   ?   B . n 
B 1 888 ARG 888 888 ?   ?   ?   B . n 
B 1 889 ASN 889 889 ?   ?   ?   B . n 
B 1 890 THR 890 890 ?   ?   ?   B . n 
B 1 891 THR 891 891 ?   ?   ?   B . n 
B 1 892 SER 892 892 ?   ?   ?   B . n 
B 1 893 THR 893 893 ?   ?   ?   B . n 
B 1 894 ARG 894 894 ?   ?   ?   B . n 
B 1 895 LYS 895 895 ?   ?   ?   B . n 
B 1 896 SER 896 896 ?   ?   ?   B . n 
B 1 897 THR 897 897 ?   ?   ?   B . n 
B 1 898 GLY 898 898 ?   ?   ?   B . n 
B 1 899 ALA 899 899 ?   ?   ?   B . n 
B 1 900 PRO 900 900 ?   ?   ?   B . n 
B 1 901 PRO 901 901 ?   ?   ?   B . n 
B 1 902 SER 902 902 ?   ?   ?   B . n 
B 1 903 SER 903 903 ?   ?   ?   B . n 
B 1 904 ALA 904 904 ?   ?   ?   B . n 
B 1 905 GLU 905 905 ?   ?   ?   B . n 
B 1 906 ASN 906 906 ?   ?   ?   B . n 
B 1 907 TRP 907 907 ?   ?   ?   B . n 
B 1 908 ASN 908 908 ?   ?   ?   B . n 
B 1 909 LEU 909 909 ?   ?   ?   B . n 
B 1 910 PRO 910 910 ?   ?   ?   B . n 
B 1 911 GLU 911 911 ?   ?   ?   B . n 
B 1 912 ASP 912 912 ?   ?   ?   B . n 
B 1 913 ARG 913 913 ?   ?   ?   B . n 
B 1 914 PRO 914 914 ?   ?   ?   B . n 
B 1 915 GLY 915 915 ?   ?   ?   B . n 
B 1 916 ALA 916 916 ?   ?   ?   B . n 
B 1 917 THR 917 917 ?   ?   ?   B . n 
B 1 918 GLY 918 918 ?   ?   ?   B . n 
B 1 919 THR 919 919 ?   ?   ?   B . n 
B 1 920 GLY 920 920 ?   ?   ?   B . n 
B 1 921 ASP 921 921 ?   ?   ?   B . n 
B 1 922 VAL 922 922 ?   ?   ?   B . n 
B 1 923 ILE 923 923 ?   ?   ?   B . n 
B 1 924 ALA 924 924 ?   ?   ?   B . n 
B 1 925 ALA 925 925 ?   ?   ?   B . n 
B 1 926 SER 926 926 ?   ?   ?   B . n 
B 1 927 PRO 927 927 ?   ?   ?   B . n 
B 1 928 GLU 928 928 ?   ?   ?   B . n 
B 1 929 THR 929 929 ?   ?   ?   B . n 
B 1 930 PRO 930 930 ?   ?   ?   B . n 
B 1 931 VAL 931 931 ?   ?   ?   B . n 
B 1 932 PRO 932 932 ?   ?   ?   B . n 
B 1 933 SER 933 933 ?   ?   ?   B . n 
B 1 934 PRO 934 934 ?   ?   ?   B . n 
B 1 935 SER 935 935 ?   ?   ?   B . n 
B 1 936 PRO 936 936 ?   ?   ?   B . n 
B 1 937 GLU 937 937 ?   ?   ?   B . n 
B 1 938 PRO 938 938 ?   ?   ?   B . n 
B 1 939 PRO 939 939 ?   ?   ?   B . n 
B 1 940 LEU 940 940 ?   ?   ?   B . n 
B 1 941 SER 941 941 ?   ?   ?   B . n 
B 1 942 LEU 942 942 ?   ?   ?   B . n 
B 1 943 ALA 943 943 ?   ?   ?   B . n 
B 1 944 PRO 944 944 ?   ?   ?   B . n 
B 1 945 GLY 945 945 ?   ?   ?   B . n 
B 1 946 LYS 946 946 ?   ?   ?   B . n 
B 1 947 VAL 947 947 ?   ?   ?   B . n 
B 1 948 GLU 948 948 ?   ?   ?   B . n 
B 1 949 GLY 949 949 ?   ?   ?   B . n 
B 1 950 GLU 950 950 ?   ?   ?   B . n 
B 1 951 LEU 951 951 ?   ?   ?   B . n 
B 1 952 GLU 952 952 ?   ?   ?   B . n 
B 1 953 GLU 953 953 ?   ?   ?   B . n 
B 1 954 LEU 954 954 ?   ?   ?   B . n 
B 1 955 GLU 955 955 ?   ?   ?   B . n 
B 1 956 LEU 956 956 ?   ?   ?   B . n 
B 1 957 VAL 957 957 ?   ?   ?   B . n 
B 1 958 GLU 958 958 ?   ?   ?   B . n 
B 1 959 SER 959 959 ?   ?   ?   B . n 
B 1 960 PRO 960 960 ?   ?   ?   B . n 
B 1 961 GLY 961 961 ?   ?   ?   B . n 
B 1 962 LEU 962 962 ?   ?   ?   B . n 
B 1 963 GLU 963 963 ?   ?   ?   B . n 
B 1 964 GLU 964 964 ?   ?   ?   B . n 
B 1 965 GLU 965 965 ?   ?   ?   B . n 
B 1 966 LEU 966 966 ?   ?   ?   B . n 
B 1 967 ALA 967 967 ?   ?   ?   B . n 
B 1 968 ASP 968 968 ?   ?   ?   B . n 
B 1 969 ILE 969 969 ?   ?   ?   B . n 
B 1 970 LEU 970 970 ?   ?   ?   B . n 
B 1 971 GLN 971 971 ?   ?   ?   B . n 
B 1 972 GLY 972 972 ?   ?   ?   B . n 
B 1 973 PRO 973 973 ?   ?   ?   B . n 
B 1 974 SER 974 974 ?   ?   ?   B . n 
B 1 975 LEU 975 975 ?   ?   ?   B . n 
B 1 976 ARG 976 976 ?   ?   ?   B . n 
B 1 977 SER 977 977 ?   ?   ?   B . n 
B 1 978 THR 978 978 ?   ?   ?   B . n 
B 1 979 ASP 979 979 ?   ?   ?   B . n 
B 1 980 GLU 980 980 ?   ?   ?   B . n 
B 1 981 GLU 981 981 ?   ?   ?   B . n 
B 1 982 ASP 982 982 ?   ?   ?   B . n 
B 1 983 GLU 983 983 ?   ?   ?   B . n 
B 1 984 ASP 984 984 ?   ?   ?   B . n 
B 1 985 GLU 985 985 ?   ?   ?   B . n 
B 1 986 LEU 986 986 ?   ?   ?   B . n 
B 1 987 ILE 987 987 ?   ?   ?   B . n 
B 1 988 LEU 988 988 ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        SCN 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   SCN 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 SCN 1 1001 605 SCN SCN A . 
D 2 SCN 1 1002 606 SCN SCN A . 
E 2 SCN 1 1003 607 SCN SCN A . 
F 2 SCN 1 1001 605 SCN SCN B . 
G 2 SCN 1 1002 606 SCN SCN B . 
H 2 SCN 1 1003 607 SCN SCN B . 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8WXJ 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8WXJ 
_struct.title                        'human CLC-1 D136G closed state' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8WXJ 
_struct_keywords.text            'Channel, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    CLCN1_HUMAN 
_struct_ref.pdbx_db_accession          P35523 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQIYGHHKEQFSDREQDIGMPK
KTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIFLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQ
FLVWVTFPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIAS
ICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLA
VWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFV
IASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIP
CGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMM
VAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLV
DSKDSMILLGSVERSELQALLQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLS
GKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRARPTKKKTTQDSTDLVDNMSPE
EIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQL
RPPLASFRNTTSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESP
GLEEELADILQGPSLRSTDEEDEDELIL
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8WXJ A 1 ? 988 ? P35523 1 ? 988 ? 1 988 
2 1 8WXJ B 1 ? 988 ? P35523 1 ? 988 ? 1 988 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8WXJ GLY A 136 ? UNP P35523 ASP 136 'engineered mutation' 136 1 
2 8WXJ GLY B 136 ? UNP P35523 ASP 136 'engineered mutation' 136 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 115 ? MET A 153 ? GLY A 115 MET A 153 1 ? 39 
HELX_P HELX_P2  AA2 SER A 156 ? SER A 183 ? SER A 156 SER A 183 1 ? 28 
HELX_P HELX_P3  AA3 GLY A 190 ? ARG A 199 ? GLY A 190 ARG A 199 1 ? 10 
HELX_P HELX_P4  AA4 THR A 208 ? GLY A 224 ? THR A 208 GLY A 224 1 ? 17 
HELX_P HELX_P5  AA5 LYS A 231 ? SER A 251 ? LYS A 231 SER A 251 1 ? 21 
HELX_P HELX_P6  AA6 TYR A 263 ? GLY A 280 ? TYR A 263 GLY A 280 1 ? 18 
HELX_P HELX_P7  AA7 THR A 281 ? SER A 294 ? THR A 281 SER A 294 1 ? 14 
HELX_P HELX_P8  AA8 VAL A 299 ? LYS A 324 ? VAL A 299 LYS A 324 1 ? 26 
HELX_P HELX_P9  AA9 GLU A 347 ? HIS A 379 ? GLU A 347 HIS A 379 1 ? 33 
HELX_P HELX_P10 AB1 HIS A 379 ? HIS A 389 ? HIS A 379 HIS A 389 1 ? 11 
HELX_P HELX_P11 AB2 LEU A 391 ? THR A 405 ? LEU A 391 THR A 405 1 ? 15 
HELX_P HELX_P12 AB3 MET A 419 ? PHE A 428 ? MET A 419 PHE A 428 1 ? 10 
HELX_P HELX_P13 AB4 LEU A 443 ? TRP A 449 ? LEU A 443 TRP A 449 5 ? 7  
HELX_P HELX_P14 AB5 ASN A 455 ? THR A 475 ? ASN A 455 THR A 475 1 ? 21 
HELX_P HELX_P15 AB6 GLY A 483 ? PHE A 506 ? GLY A 483 PHE A 506 1 ? 24 
HELX_P HELX_P16 AB7 LEU A 520 ? SER A 537 ? LEU A 520 SER A 537 1 ? 18 
HELX_P HELX_P17 AB8 SER A 541 ? THR A 550 ? SER A 541 THR A 550 1 ? 10 
HELX_P HELX_P18 AB9 HIS A 555 ? GLN A 574 ? HIS A 555 GLN A 574 1 ? 20 
HELX_P HELX_P19 AC1 SER A 576 ? LYS A 585 ? SER A 576 LYS A 585 1 ? 10 
HELX_P HELX_P20 AC2 GLU B 116 ? MET B 153 ? GLU B 116 MET B 153 1 ? 38 
HELX_P HELX_P21 AC3 SER B 156 ? SER B 183 ? SER B 156 SER B 183 1 ? 28 
HELX_P HELX_P22 AC4 GLY B 190 ? ARG B 199 ? GLY B 190 ARG B 199 1 ? 10 
HELX_P HELX_P23 AC5 THR B 208 ? GLY B 224 ? THR B 208 GLY B 224 1 ? 17 
HELX_P HELX_P24 AC6 LYS B 231 ? SER B 251 ? LYS B 231 SER B 251 1 ? 21 
HELX_P HELX_P25 AC7 TYR B 263 ? GLY B 280 ? TYR B 263 GLY B 280 1 ? 18 
HELX_P HELX_P26 AC8 THR B 281 ? SER B 294 ? THR B 281 SER B 294 1 ? 14 
HELX_P HELX_P27 AC9 VAL B 299 ? LYS B 324 ? VAL B 299 LYS B 324 1 ? 26 
HELX_P HELX_P28 AD1 GLU B 347 ? HIS B 379 ? GLU B 347 HIS B 379 1 ? 33 
HELX_P HELX_P29 AD2 HIS B 379 ? HIS B 389 ? HIS B 379 HIS B 389 1 ? 11 
HELX_P HELX_P30 AD3 LEU B 391 ? THR B 405 ? LEU B 391 THR B 405 1 ? 15 
HELX_P HELX_P31 AD4 MET B 419 ? PHE B 428 ? MET B 419 PHE B 428 1 ? 10 
HELX_P HELX_P32 AD5 LEU B 443 ? TRP B 449 ? LEU B 443 TRP B 449 5 ? 7  
HELX_P HELX_P33 AD6 ASN B 455 ? THR B 475 ? ASN B 455 THR B 475 1 ? 21 
HELX_P HELX_P34 AD7 GLY B 483 ? PHE B 506 ? GLY B 483 PHE B 506 1 ? 24 
HELX_P HELX_P35 AD8 LEU B 520 ? SER B 537 ? LEU B 520 SER B 537 1 ? 18 
HELX_P HELX_P36 AD9 SER B 541 ? THR B 550 ? SER B 541 THR B 550 1 ? 10 
HELX_P HELX_P37 AE1 HIS B 555 ? GLN B 574 ? HIS B 555 GLN B 574 1 ? 20 
HELX_P HELX_P38 AE2 SER B 576 ? LYS B 585 ? SER B 576 LYS B 585 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 TYR A 296 ? ALA A 298 ? TYR A 296 ALA A 298 
AA1 2 TYR B 296 ? ALA B 298 ? TYR B 296 ALA B 298 
AA2 1 ILE A 510 ? LEU A 511 ? ILE A 510 LEU A 511 
AA2 2 ILE A 516 ? TYR A 517 ? ILE A 516 TYR A 517 
AA3 1 ILE B 510 ? LEU B 511 ? ILE B 510 LEU B 511 
AA3 2 ILE B 516 ? TYR B 517 ? ILE B 516 TYR B 517 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 297 ? N PHE A 297 O PHE B 297 ? O PHE B 297 
AA2 1 2 N ILE A 510 ? N ILE A 510 O TYR A 517 ? O TYR A 517 
AA3 1 2 N ILE B 510 ? N ILE B 510 O TYR B 517 ? O TYR B 517 
# 
_pdbx_entry_details.entry_id                   8WXJ 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ILE A 182 ? ? -68.83  -72.01  
2  1 ALA A 186 ? ? -95.32  32.05   
3  1 SER A 189 ? ? 56.59   -162.94 
4  1 LEU A 203 ? ? -90.91  -157.56 
5  1 LYS A 204 ? ? -80.98  -104.08 
6  1 GLU A 205 ? ? -103.27 47.56   
7  1 LEU A 207 ? ? -93.17  48.07   
8  1 PRO A 228 ? ? -68.74  81.31   
9  1 LYS A 231 ? ? -132.59 -37.65  
10 1 LYS A 324 ? ? 43.07   -104.01 
11 1 ASP A 325 ? ? -52.68  -73.13  
12 1 ALA A 326 ? ? 33.81   -112.92 
13 1 ILE A 329 ? ? -58.31  100.52  
14 1 PHE A 343 ? ? 71.90   132.40  
15 1 MET A 414 ? ? -144.70 16.68   
16 1 PHE A 428 ? ? -99.85  31.55   
17 1 HIS A 436 ? ? -98.89  45.22   
18 1 PRO A 440 ? ? -85.70  -158.41 
19 1 SER A 442 ? ? -148.55 -11.58  
20 1 ARG A 453 ? ? -100.66 -66.33  
21 1 PHE A 512 ? ? -105.99 -99.83  
22 1 ASP A 514 ? ? -140.18 15.57   
23 1 THR A 550 ? ? -124.89 -139.52 
24 1 GLN A 552 ? ? -121.35 -75.11  
25 1 LEU A 573 ? ? -98.37  -65.22  
26 1 ILE B 182 ? ? -68.83  -72.01  
27 1 ALA B 186 ? ? -95.32  32.05   
28 1 SER B 189 ? ? 56.59   -162.94 
29 1 LEU B 203 ? ? -90.91  -157.56 
30 1 LYS B 204 ? ? -80.98  -104.08 
31 1 GLU B 205 ? ? -103.27 47.56   
32 1 LEU B 207 ? ? -93.17  48.07   
33 1 PRO B 228 ? ? -68.74  81.31   
34 1 LYS B 231 ? ? -132.59 -37.65  
35 1 LYS B 324 ? ? 43.07   -104.01 
36 1 ASP B 325 ? ? -52.68  -73.13  
37 1 ALA B 326 ? ? 33.81   -112.92 
38 1 ILE B 329 ? ? -58.31  100.52  
39 1 PHE B 343 ? ? 71.90   132.40  
40 1 MET B 414 ? ? -144.70 16.68   
41 1 PHE B 428 ? ? -99.85  31.55   
42 1 HIS B 436 ? ? -98.89  45.22   
43 1 PRO B 440 ? ? -85.70  -158.41 
44 1 SER B 442 ? ? -148.55 -11.58  
45 1 ARG B 453 ? ? -100.66 -66.33  
46 1 PHE B 512 ? ? -105.99 -99.83  
47 1 ASP B 514 ? ? -140.18 15.57   
48 1 THR B 550 ? ? -124.89 -139.52 
49 1 GLN B 552 ? ? -121.35 -75.11  
50 1 LEU B 573 ? ? -98.37  -65.22  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8WXJ 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8WXJ 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.68 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               36886 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'CLC-1 channel' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8WXJ 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             1800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8WXJ 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8WXJ 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1    1 Y 1 A MET 1   ? A MET 1   
2    1 Y 1 A GLU 2   ? A GLU 2   
3    1 Y 1 A GLN 3   ? A GLN 3   
4    1 Y 1 A SER 4   ? A SER 4   
5    1 Y 1 A ARG 5   ? A ARG 5   
6    1 Y 1 A SER 6   ? A SER 6   
7    1 Y 1 A GLN 7   ? A GLN 7   
8    1 Y 1 A GLN 8   ? A GLN 8   
9    1 Y 1 A ARG 9   ? A ARG 9   
10   1 Y 1 A GLY 10  ? A GLY 10  
11   1 Y 1 A GLY 11  ? A GLY 11  
12   1 Y 1 A GLU 12  ? A GLU 12  
13   1 Y 1 A GLN 13  ? A GLN 13  
14   1 Y 1 A SER 14  ? A SER 14  
15   1 Y 1 A TRP 15  ? A TRP 15  
16   1 Y 1 A TRP 16  ? A TRP 16  
17   1 Y 1 A GLY 17  ? A GLY 17  
18   1 Y 1 A SER 18  ? A SER 18  
19   1 Y 1 A ASP 19  ? A ASP 19  
20   1 Y 1 A PRO 20  ? A PRO 20  
21   1 Y 1 A GLN 21  ? A GLN 21  
22   1 Y 1 A TYR 22  ? A TYR 22  
23   1 Y 1 A GLN 23  ? A GLN 23  
24   1 Y 1 A TYR 24  ? A TYR 24  
25   1 Y 1 A MET 25  ? A MET 25  
26   1 Y 1 A PRO 26  ? A PRO 26  
27   1 Y 1 A PHE 27  ? A PHE 27  
28   1 Y 1 A GLU 28  ? A GLU 28  
29   1 Y 1 A HIS 29  ? A HIS 29  
30   1 Y 1 A CYS 30  ? A CYS 30  
31   1 Y 1 A THR 31  ? A THR 31  
32   1 Y 1 A SER 32  ? A SER 32  
33   1 Y 1 A TYR 33  ? A TYR 33  
34   1 Y 1 A GLY 34  ? A GLY 34  
35   1 Y 1 A LEU 35  ? A LEU 35  
36   1 Y 1 A PRO 36  ? A PRO 36  
37   1 Y 1 A SER 37  ? A SER 37  
38   1 Y 1 A GLU 38  ? A GLU 38  
39   1 Y 1 A ASN 39  ? A ASN 39  
40   1 Y 1 A GLY 40  ? A GLY 40  
41   1 Y 1 A GLY 41  ? A GLY 41  
42   1 Y 1 A LEU 42  ? A LEU 42  
43   1 Y 1 A GLN 43  ? A GLN 43  
44   1 Y 1 A HIS 44  ? A HIS 44  
45   1 Y 1 A ARG 45  ? A ARG 45  
46   1 Y 1 A LEU 46  ? A LEU 46  
47   1 Y 1 A ARG 47  ? A ARG 47  
48   1 Y 1 A LYS 48  ? A LYS 48  
49   1 Y 1 A ASP 49  ? A ASP 49  
50   1 Y 1 A ALA 50  ? A ALA 50  
51   1 Y 1 A GLY 51  ? A GLY 51  
52   1 Y 1 A PRO 52  ? A PRO 52  
53   1 Y 1 A ARG 53  ? A ARG 53  
54   1 Y 1 A HIS 54  ? A HIS 54  
55   1 Y 1 A ASN 55  ? A ASN 55  
56   1 Y 1 A VAL 56  ? A VAL 56  
57   1 Y 1 A HIS 57  ? A HIS 57  
58   1 Y 1 A PRO 58  ? A PRO 58  
59   1 Y 1 A THR 59  ? A THR 59  
60   1 Y 1 A GLN 60  ? A GLN 60  
61   1 Y 1 A ILE 61  ? A ILE 61  
62   1 Y 1 A TYR 62  ? A TYR 62  
63   1 Y 1 A GLY 63  ? A GLY 63  
64   1 Y 1 A HIS 64  ? A HIS 64  
65   1 Y 1 A HIS 65  ? A HIS 65  
66   1 Y 1 A LYS 66  ? A LYS 66  
67   1 Y 1 A GLU 67  ? A GLU 67  
68   1 Y 1 A GLN 68  ? A GLN 68  
69   1 Y 1 A PHE 69  ? A PHE 69  
70   1 Y 1 A SER 70  ? A SER 70  
71   1 Y 1 A ASP 71  ? A ASP 71  
72   1 Y 1 A ARG 72  ? A ARG 72  
73   1 Y 1 A GLU 73  ? A GLU 73  
74   1 Y 1 A GLN 74  ? A GLN 74  
75   1 Y 1 A ASP 75  ? A ASP 75  
76   1 Y 1 A ILE 76  ? A ILE 76  
77   1 Y 1 A GLY 77  ? A GLY 77  
78   1 Y 1 A MET 78  ? A MET 78  
79   1 Y 1 A PRO 79  ? A PRO 79  
80   1 Y 1 A LYS 80  ? A LYS 80  
81   1 Y 1 A LYS 81  ? A LYS 81  
82   1 Y 1 A THR 82  ? A THR 82  
83   1 Y 1 A GLY 83  ? A GLY 83  
84   1 Y 1 A SER 84  ? A SER 84  
85   1 Y 1 A SER 85  ? A SER 85  
86   1 Y 1 A SER 86  ? A SER 86  
87   1 Y 1 A THR 87  ? A THR 87  
88   1 Y 1 A VAL 88  ? A VAL 88  
89   1 Y 1 A ASP 89  ? A ASP 89  
90   1 Y 1 A SER 90  ? A SER 90  
91   1 Y 1 A LYS 91  ? A LYS 91  
92   1 Y 1 A ASP 92  ? A ASP 92  
93   1 Y 1 A GLU 93  ? A GLU 93  
94   1 Y 1 A ASP 94  ? A ASP 94  
95   1 Y 1 A HIS 95  ? A HIS 95  
96   1 Y 1 A TYR 96  ? A TYR 96  
97   1 Y 1 A SER 97  ? A SER 97  
98   1 Y 1 A LYS 98  ? A LYS 98  
99   1 Y 1 A CYS 99  ? A CYS 99  
100  1 Y 1 A GLN 100 ? A GLN 100 
101  1 Y 1 A ASP 101 ? A ASP 101 
102  1 Y 1 A CYS 102 ? A CYS 102 
103  1 Y 1 A ILE 103 ? A ILE 103 
104  1 Y 1 A HIS 104 ? A HIS 104 
105  1 Y 1 A ARG 105 ? A ARG 105 
106  1 Y 1 A LEU 106 ? A LEU 106 
107  1 Y 1 A GLY 107 ? A GLY 107 
108  1 Y 1 A GLN 108 ? A GLN 108 
109  1 Y 1 A VAL 109 ? A VAL 109 
110  1 Y 1 A VAL 110 ? A VAL 110 
111  1 Y 1 A ARG 111 ? A ARG 111 
112  1 Y 1 A ARG 112 ? A ARG 112 
113  1 Y 1 A LYS 113 ? A LYS 113 
114  1 Y 1 A LEU 114 ? A LEU 114 
115  1 Y 1 A CYS 254 ? A CYS 254 
116  1 Y 1 A GLY 255 ? A GLY 255 
117  1 Y 1 A VAL 256 ? A VAL 256 
118  1 Y 1 A TYR 257 ? A TYR 257 
119  1 Y 1 A GLU 258 ? A GLU 258 
120  1 Y 1 A GLN 259 ? A GLN 259 
121  1 Y 1 A PRO 260 ? A PRO 260 
122  1 Y 1 A TYR 261 ? A TYR 261 
123  1 Y 1 A LEU 590 ? A LEU 590 
124  1 Y 1 A PRO 591 ? A PRO 591 
125  1 Y 1 A ASP 592 ? A ASP 592 
126  1 Y 1 A LEU 593 ? A LEU 593 
127  1 Y 1 A GLY 594 ? A GLY 594 
128  1 Y 1 A TRP 595 ? A TRP 595 
129  1 Y 1 A ASN 596 ? A ASN 596 
130  1 Y 1 A GLN 597 ? A GLN 597 
131  1 Y 1 A LEU 598 ? A LEU 598 
132  1 Y 1 A SER 599 ? A SER 599 
133  1 Y 1 A LYS 600 ? A LYS 600 
134  1 Y 1 A TYR 601 ? A TYR 601 
135  1 Y 1 A THR 602 ? A THR 602 
136  1 Y 1 A ILE 603 ? A ILE 603 
137  1 Y 1 A PHE 604 ? A PHE 604 
138  1 Y 1 A VAL 605 ? A VAL 605 
139  1 Y 1 A GLU 606 ? A GLU 606 
140  1 Y 1 A ASP 607 ? A ASP 607 
141  1 Y 1 A ILE 608 ? A ILE 608 
142  1 Y 1 A MET 609 ? A MET 609 
143  1 Y 1 A VAL 610 ? A VAL 610 
144  1 Y 1 A ARG 611 ? A ARG 611 
145  1 Y 1 A ASP 612 ? A ASP 612 
146  1 Y 1 A VAL 613 ? A VAL 613 
147  1 Y 1 A LYS 614 ? A LYS 614 
148  1 Y 1 A PHE 615 ? A PHE 615 
149  1 Y 1 A VAL 616 ? A VAL 616 
150  1 Y 1 A SER 617 ? A SER 617 
151  1 Y 1 A ALA 618 ? A ALA 618 
152  1 Y 1 A SER 619 ? A SER 619 
153  1 Y 1 A TYR 620 ? A TYR 620 
154  1 Y 1 A THR 621 ? A THR 621 
155  1 Y 1 A TYR 622 ? A TYR 622 
156  1 Y 1 A GLY 623 ? A GLY 623 
157  1 Y 1 A GLU 624 ? A GLU 624 
158  1 Y 1 A LEU 625 ? A LEU 625 
159  1 Y 1 A ARG 626 ? A ARG 626 
160  1 Y 1 A THR 627 ? A THR 627 
161  1 Y 1 A LEU 628 ? A LEU 628 
162  1 Y 1 A LEU 629 ? A LEU 629 
163  1 Y 1 A GLN 630 ? A GLN 630 
164  1 Y 1 A THR 631 ? A THR 631 
165  1 Y 1 A THR 632 ? A THR 632 
166  1 Y 1 A THR 633 ? A THR 633 
167  1 Y 1 A VAL 634 ? A VAL 634 
168  1 Y 1 A LYS 635 ? A LYS 635 
169  1 Y 1 A THR 636 ? A THR 636 
170  1 Y 1 A LEU 637 ? A LEU 637 
171  1 Y 1 A PRO 638 ? A PRO 638 
172  1 Y 1 A LEU 639 ? A LEU 639 
173  1 Y 1 A VAL 640 ? A VAL 640 
174  1 Y 1 A ASP 641 ? A ASP 641 
175  1 Y 1 A SER 642 ? A SER 642 
176  1 Y 1 A LYS 643 ? A LYS 643 
177  1 Y 1 A ASP 644 ? A ASP 644 
178  1 Y 1 A SER 645 ? A SER 645 
179  1 Y 1 A MET 646 ? A MET 646 
180  1 Y 1 A ILE 647 ? A ILE 647 
181  1 Y 1 A LEU 648 ? A LEU 648 
182  1 Y 1 A LEU 649 ? A LEU 649 
183  1 Y 1 A GLY 650 ? A GLY 650 
184  1 Y 1 A SER 651 ? A SER 651 
185  1 Y 1 A VAL 652 ? A VAL 652 
186  1 Y 1 A GLU 653 ? A GLU 653 
187  1 Y 1 A ARG 654 ? A ARG 654 
188  1 Y 1 A SER 655 ? A SER 655 
189  1 Y 1 A GLU 656 ? A GLU 656 
190  1 Y 1 A LEU 657 ? A LEU 657 
191  1 Y 1 A GLN 658 ? A GLN 658 
192  1 Y 1 A ALA 659 ? A ALA 659 
193  1 Y 1 A LEU 660 ? A LEU 660 
194  1 Y 1 A LEU 661 ? A LEU 661 
195  1 Y 1 A GLN 662 ? A GLN 662 
196  1 Y 1 A ARG 663 ? A ARG 663 
197  1 Y 1 A HIS 664 ? A HIS 664 
198  1 Y 1 A LEU 665 ? A LEU 665 
199  1 Y 1 A CYS 666 ? A CYS 666 
200  1 Y 1 A PRO 667 ? A PRO 667 
201  1 Y 1 A GLU 668 ? A GLU 668 
202  1 Y 1 A ARG 669 ? A ARG 669 
203  1 Y 1 A ARG 670 ? A ARG 670 
204  1 Y 1 A LEU 671 ? A LEU 671 
205  1 Y 1 A ARG 672 ? A ARG 672 
206  1 Y 1 A ALA 673 ? A ALA 673 
207  1 Y 1 A ALA 674 ? A ALA 674 
208  1 Y 1 A GLN 675 ? A GLN 675 
209  1 Y 1 A GLU 676 ? A GLU 676 
210  1 Y 1 A MET 677 ? A MET 677 
211  1 Y 1 A ALA 678 ? A ALA 678 
212  1 Y 1 A ARG 679 ? A ARG 679 
213  1 Y 1 A LYS 680 ? A LYS 680 
214  1 Y 1 A LEU 681 ? A LEU 681 
215  1 Y 1 A SER 682 ? A SER 682 
216  1 Y 1 A GLU 683 ? A GLU 683 
217  1 Y 1 A LEU 684 ? A LEU 684 
218  1 Y 1 A PRO 685 ? A PRO 685 
219  1 Y 1 A TYR 686 ? A TYR 686 
220  1 Y 1 A ASP 687 ? A ASP 687 
221  1 Y 1 A GLY 688 ? A GLY 688 
222  1 Y 1 A LYS 689 ? A LYS 689 
223  1 Y 1 A ALA 690 ? A ALA 690 
224  1 Y 1 A ARG 691 ? A ARG 691 
225  1 Y 1 A LEU 692 ? A LEU 692 
226  1 Y 1 A ALA 693 ? A ALA 693 
227  1 Y 1 A GLY 694 ? A GLY 694 
228  1 Y 1 A GLU 695 ? A GLU 695 
229  1 Y 1 A GLY 696 ? A GLY 696 
230  1 Y 1 A LEU 697 ? A LEU 697 
231  1 Y 1 A PRO 698 ? A PRO 698 
232  1 Y 1 A GLY 699 ? A GLY 699 
233  1 Y 1 A ALA 700 ? A ALA 700 
234  1 Y 1 A PRO 701 ? A PRO 701 
235  1 Y 1 A PRO 702 ? A PRO 702 
236  1 Y 1 A GLY 703 ? A GLY 703 
237  1 Y 1 A ARG 704 ? A ARG 704 
238  1 Y 1 A PRO 705 ? A PRO 705 
239  1 Y 1 A GLU 706 ? A GLU 706 
240  1 Y 1 A SER 707 ? A SER 707 
241  1 Y 1 A PHE 708 ? A PHE 708 
242  1 Y 1 A ALA 709 ? A ALA 709 
243  1 Y 1 A PHE 710 ? A PHE 710 
244  1 Y 1 A VAL 711 ? A VAL 711 
245  1 Y 1 A ASP 712 ? A ASP 712 
246  1 Y 1 A GLU 713 ? A GLU 713 
247  1 Y 1 A ASP 714 ? A ASP 714 
248  1 Y 1 A GLU 715 ? A GLU 715 
249  1 Y 1 A ASP 716 ? A ASP 716 
250  1 Y 1 A GLU 717 ? A GLU 717 
251  1 Y 1 A ASP 718 ? A ASP 718 
252  1 Y 1 A LEU 719 ? A LEU 719 
253  1 Y 1 A SER 720 ? A SER 720 
254  1 Y 1 A GLY 721 ? A GLY 721 
255  1 Y 1 A LYS 722 ? A LYS 722 
256  1 Y 1 A SER 723 ? A SER 723 
257  1 Y 1 A GLU 724 ? A GLU 724 
258  1 Y 1 A LEU 725 ? A LEU 725 
259  1 Y 1 A PRO 726 ? A PRO 726 
260  1 Y 1 A PRO 727 ? A PRO 727 
261  1 Y 1 A SER 728 ? A SER 728 
262  1 Y 1 A LEU 729 ? A LEU 729 
263  1 Y 1 A ALA 730 ? A ALA 730 
264  1 Y 1 A LEU 731 ? A LEU 731 
265  1 Y 1 A HIS 732 ? A HIS 732 
266  1 Y 1 A PRO 733 ? A PRO 733 
267  1 Y 1 A SER 734 ? A SER 734 
268  1 Y 1 A THR 735 ? A THR 735 
269  1 Y 1 A THR 736 ? A THR 736 
270  1 Y 1 A ALA 737 ? A ALA 737 
271  1 Y 1 A PRO 738 ? A PRO 738 
272  1 Y 1 A LEU 739 ? A LEU 739 
273  1 Y 1 A SER 740 ? A SER 740 
274  1 Y 1 A PRO 741 ? A PRO 741 
275  1 Y 1 A GLU 742 ? A GLU 742 
276  1 Y 1 A GLU 743 ? A GLU 743 
277  1 Y 1 A PRO 744 ? A PRO 744 
278  1 Y 1 A ASN 745 ? A ASN 745 
279  1 Y 1 A GLY 746 ? A GLY 746 
280  1 Y 1 A PRO 747 ? A PRO 747 
281  1 Y 1 A LEU 748 ? A LEU 748 
282  1 Y 1 A PRO 749 ? A PRO 749 
283  1 Y 1 A GLY 750 ? A GLY 750 
284  1 Y 1 A HIS 751 ? A HIS 751 
285  1 Y 1 A LYS 752 ? A LYS 752 
286  1 Y 1 A GLN 753 ? A GLN 753 
287  1 Y 1 A GLN 754 ? A GLN 754 
288  1 Y 1 A PRO 755 ? A PRO 755 
289  1 Y 1 A GLU 756 ? A GLU 756 
290  1 Y 1 A ALA 757 ? A ALA 757 
291  1 Y 1 A PRO 758 ? A PRO 758 
292  1 Y 1 A GLU 759 ? A GLU 759 
293  1 Y 1 A PRO 760 ? A PRO 760 
294  1 Y 1 A ALA 761 ? A ALA 761 
295  1 Y 1 A GLY 762 ? A GLY 762 
296  1 Y 1 A GLN 763 ? A GLN 763 
297  1 Y 1 A ARG 764 ? A ARG 764 
298  1 Y 1 A PRO 765 ? A PRO 765 
299  1 Y 1 A SER 766 ? A SER 766 
300  1 Y 1 A ILE 767 ? A ILE 767 
301  1 Y 1 A PHE 768 ? A PHE 768 
302  1 Y 1 A GLN 769 ? A GLN 769 
303  1 Y 1 A SER 770 ? A SER 770 
304  1 Y 1 A LEU 771 ? A LEU 771 
305  1 Y 1 A LEU 772 ? A LEU 772 
306  1 Y 1 A HIS 773 ? A HIS 773 
307  1 Y 1 A CYS 774 ? A CYS 774 
308  1 Y 1 A LEU 775 ? A LEU 775 
309  1 Y 1 A LEU 776 ? A LEU 776 
310  1 Y 1 A GLY 777 ? A GLY 777 
311  1 Y 1 A ARG 778 ? A ARG 778 
312  1 Y 1 A ALA 779 ? A ALA 779 
313  1 Y 1 A ARG 780 ? A ARG 780 
314  1 Y 1 A PRO 781 ? A PRO 781 
315  1 Y 1 A THR 782 ? A THR 782 
316  1 Y 1 A LYS 783 ? A LYS 783 
317  1 Y 1 A LYS 784 ? A LYS 784 
318  1 Y 1 A LYS 785 ? A LYS 785 
319  1 Y 1 A THR 786 ? A THR 786 
320  1 Y 1 A THR 787 ? A THR 787 
321  1 Y 1 A GLN 788 ? A GLN 788 
322  1 Y 1 A ASP 789 ? A ASP 789 
323  1 Y 1 A SER 790 ? A SER 790 
324  1 Y 1 A THR 791 ? A THR 791 
325  1 Y 1 A ASP 792 ? A ASP 792 
326  1 Y 1 A LEU 793 ? A LEU 793 
327  1 Y 1 A VAL 794 ? A VAL 794 
328  1 Y 1 A ASP 795 ? A ASP 795 
329  1 Y 1 A ASN 796 ? A ASN 796 
330  1 Y 1 A MET 797 ? A MET 797 
331  1 Y 1 A SER 798 ? A SER 798 
332  1 Y 1 A PRO 799 ? A PRO 799 
333  1 Y 1 A GLU 800 ? A GLU 800 
334  1 Y 1 A GLU 801 ? A GLU 801 
335  1 Y 1 A ILE 802 ? A ILE 802 
336  1 Y 1 A GLU 803 ? A GLU 803 
337  1 Y 1 A ALA 804 ? A ALA 804 
338  1 Y 1 A TRP 805 ? A TRP 805 
339  1 Y 1 A GLU 806 ? A GLU 806 
340  1 Y 1 A GLN 807 ? A GLN 807 
341  1 Y 1 A GLU 808 ? A GLU 808 
342  1 Y 1 A GLN 809 ? A GLN 809 
343  1 Y 1 A LEU 810 ? A LEU 810 
344  1 Y 1 A SER 811 ? A SER 811 
345  1 Y 1 A GLN 812 ? A GLN 812 
346  1 Y 1 A PRO 813 ? A PRO 813 
347  1 Y 1 A VAL 814 ? A VAL 814 
348  1 Y 1 A CYS 815 ? A CYS 815 
349  1 Y 1 A PHE 816 ? A PHE 816 
350  1 Y 1 A ASP 817 ? A ASP 817 
351  1 Y 1 A SER 818 ? A SER 818 
352  1 Y 1 A CYS 819 ? A CYS 819 
353  1 Y 1 A CYS 820 ? A CYS 820 
354  1 Y 1 A ILE 821 ? A ILE 821 
355  1 Y 1 A ASP 822 ? A ASP 822 
356  1 Y 1 A GLN 823 ? A GLN 823 
357  1 Y 1 A SER 824 ? A SER 824 
358  1 Y 1 A PRO 825 ? A PRO 825 
359  1 Y 1 A PHE 826 ? A PHE 826 
360  1 Y 1 A GLN 827 ? A GLN 827 
361  1 Y 1 A LEU 828 ? A LEU 828 
362  1 Y 1 A VAL 829 ? A VAL 829 
363  1 Y 1 A GLU 830 ? A GLU 830 
364  1 Y 1 A GLN 831 ? A GLN 831 
365  1 Y 1 A THR 832 ? A THR 832 
366  1 Y 1 A THR 833 ? A THR 833 
367  1 Y 1 A LEU 834 ? A LEU 834 
368  1 Y 1 A HIS 835 ? A HIS 835 
369  1 Y 1 A LYS 836 ? A LYS 836 
370  1 Y 1 A THR 837 ? A THR 837 
371  1 Y 1 A HIS 838 ? A HIS 838 
372  1 Y 1 A THR 839 ? A THR 839 
373  1 Y 1 A LEU 840 ? A LEU 840 
374  1 Y 1 A PHE 841 ? A PHE 841 
375  1 Y 1 A SER 842 ? A SER 842 
376  1 Y 1 A LEU 843 ? A LEU 843 
377  1 Y 1 A LEU 844 ? A LEU 844 
378  1 Y 1 A GLY 845 ? A GLY 845 
379  1 Y 1 A LEU 846 ? A LEU 846 
380  1 Y 1 A HIS 847 ? A HIS 847 
381  1 Y 1 A LEU 848 ? A LEU 848 
382  1 Y 1 A ALA 849 ? A ALA 849 
383  1 Y 1 A TYR 850 ? A TYR 850 
384  1 Y 1 A VAL 851 ? A VAL 851 
385  1 Y 1 A THR 852 ? A THR 852 
386  1 Y 1 A SER 853 ? A SER 853 
387  1 Y 1 A MET 854 ? A MET 854 
388  1 Y 1 A GLY 855 ? A GLY 855 
389  1 Y 1 A LYS 856 ? A LYS 856 
390  1 Y 1 A LEU 857 ? A LEU 857 
391  1 Y 1 A ARG 858 ? A ARG 858 
392  1 Y 1 A GLY 859 ? A GLY 859 
393  1 Y 1 A VAL 860 ? A VAL 860 
394  1 Y 1 A LEU 861 ? A LEU 861 
395  1 Y 1 A ALA 862 ? A ALA 862 
396  1 Y 1 A LEU 863 ? A LEU 863 
397  1 Y 1 A GLU 864 ? A GLU 864 
398  1 Y 1 A GLU 865 ? A GLU 865 
399  1 Y 1 A LEU 866 ? A LEU 866 
400  1 Y 1 A GLN 867 ? A GLN 867 
401  1 Y 1 A LYS 868 ? A LYS 868 
402  1 Y 1 A ALA 869 ? A ALA 869 
403  1 Y 1 A ILE 870 ? A ILE 870 
404  1 Y 1 A GLU 871 ? A GLU 871 
405  1 Y 1 A GLY 872 ? A GLY 872 
406  1 Y 1 A HIS 873 ? A HIS 873 
407  1 Y 1 A THR 874 ? A THR 874 
408  1 Y 1 A LYS 875 ? A LYS 875 
409  1 Y 1 A SER 876 ? A SER 876 
410  1 Y 1 A GLY 877 ? A GLY 877 
411  1 Y 1 A VAL 878 ? A VAL 878 
412  1 Y 1 A GLN 879 ? A GLN 879 
413  1 Y 1 A LEU 880 ? A LEU 880 
414  1 Y 1 A ARG 881 ? A ARG 881 
415  1 Y 1 A PRO 882 ? A PRO 882 
416  1 Y 1 A PRO 883 ? A PRO 883 
417  1 Y 1 A LEU 884 ? A LEU 884 
418  1 Y 1 A ALA 885 ? A ALA 885 
419  1 Y 1 A SER 886 ? A SER 886 
420  1 Y 1 A PHE 887 ? A PHE 887 
421  1 Y 1 A ARG 888 ? A ARG 888 
422  1 Y 1 A ASN 889 ? A ASN 889 
423  1 Y 1 A THR 890 ? A THR 890 
424  1 Y 1 A THR 891 ? A THR 891 
425  1 Y 1 A SER 892 ? A SER 892 
426  1 Y 1 A THR 893 ? A THR 893 
427  1 Y 1 A ARG 894 ? A ARG 894 
428  1 Y 1 A LYS 895 ? A LYS 895 
429  1 Y 1 A SER 896 ? A SER 896 
430  1 Y 1 A THR 897 ? A THR 897 
431  1 Y 1 A GLY 898 ? A GLY 898 
432  1 Y 1 A ALA 899 ? A ALA 899 
433  1 Y 1 A PRO 900 ? A PRO 900 
434  1 Y 1 A PRO 901 ? A PRO 901 
435  1 Y 1 A SER 902 ? A SER 902 
436  1 Y 1 A SER 903 ? A SER 903 
437  1 Y 1 A ALA 904 ? A ALA 904 
438  1 Y 1 A GLU 905 ? A GLU 905 
439  1 Y 1 A ASN 906 ? A ASN 906 
440  1 Y 1 A TRP 907 ? A TRP 907 
441  1 Y 1 A ASN 908 ? A ASN 908 
442  1 Y 1 A LEU 909 ? A LEU 909 
443  1 Y 1 A PRO 910 ? A PRO 910 
444  1 Y 1 A GLU 911 ? A GLU 911 
445  1 Y 1 A ASP 912 ? A ASP 912 
446  1 Y 1 A ARG 913 ? A ARG 913 
447  1 Y 1 A PRO 914 ? A PRO 914 
448  1 Y 1 A GLY 915 ? A GLY 915 
449  1 Y 1 A ALA 916 ? A ALA 916 
450  1 Y 1 A THR 917 ? A THR 917 
451  1 Y 1 A GLY 918 ? A GLY 918 
452  1 Y 1 A THR 919 ? A THR 919 
453  1 Y 1 A GLY 920 ? A GLY 920 
454  1 Y 1 A ASP 921 ? A ASP 921 
455  1 Y 1 A VAL 922 ? A VAL 922 
456  1 Y 1 A ILE 923 ? A ILE 923 
457  1 Y 1 A ALA 924 ? A ALA 924 
458  1 Y 1 A ALA 925 ? A ALA 925 
459  1 Y 1 A SER 926 ? A SER 926 
460  1 Y 1 A PRO 927 ? A PRO 927 
461  1 Y 1 A GLU 928 ? A GLU 928 
462  1 Y 1 A THR 929 ? A THR 929 
463  1 Y 1 A PRO 930 ? A PRO 930 
464  1 Y 1 A VAL 931 ? A VAL 931 
465  1 Y 1 A PRO 932 ? A PRO 932 
466  1 Y 1 A SER 933 ? A SER 933 
467  1 Y 1 A PRO 934 ? A PRO 934 
468  1 Y 1 A SER 935 ? A SER 935 
469  1 Y 1 A PRO 936 ? A PRO 936 
470  1 Y 1 A GLU 937 ? A GLU 937 
471  1 Y 1 A PRO 938 ? A PRO 938 
472  1 Y 1 A PRO 939 ? A PRO 939 
473  1 Y 1 A LEU 940 ? A LEU 940 
474  1 Y 1 A SER 941 ? A SER 941 
475  1 Y 1 A LEU 942 ? A LEU 942 
476  1 Y 1 A ALA 943 ? A ALA 943 
477  1 Y 1 A PRO 944 ? A PRO 944 
478  1 Y 1 A GLY 945 ? A GLY 945 
479  1 Y 1 A LYS 946 ? A LYS 946 
480  1 Y 1 A VAL 947 ? A VAL 947 
481  1 Y 1 A GLU 948 ? A GLU 948 
482  1 Y 1 A GLY 949 ? A GLY 949 
483  1 Y 1 A GLU 950 ? A GLU 950 
484  1 Y 1 A LEU 951 ? A LEU 951 
485  1 Y 1 A GLU 952 ? A GLU 952 
486  1 Y 1 A GLU 953 ? A GLU 953 
487  1 Y 1 A LEU 954 ? A LEU 954 
488  1 Y 1 A GLU 955 ? A GLU 955 
489  1 Y 1 A LEU 956 ? A LEU 956 
490  1 Y 1 A VAL 957 ? A VAL 957 
491  1 Y 1 A GLU 958 ? A GLU 958 
492  1 Y 1 A SER 959 ? A SER 959 
493  1 Y 1 A PRO 960 ? A PRO 960 
494  1 Y 1 A GLY 961 ? A GLY 961 
495  1 Y 1 A LEU 962 ? A LEU 962 
496  1 Y 1 A GLU 963 ? A GLU 963 
497  1 Y 1 A GLU 964 ? A GLU 964 
498  1 Y 1 A GLU 965 ? A GLU 965 
499  1 Y 1 A LEU 966 ? A LEU 966 
500  1 Y 1 A ALA 967 ? A ALA 967 
501  1 Y 1 A ASP 968 ? A ASP 968 
502  1 Y 1 A ILE 969 ? A ILE 969 
503  1 Y 1 A LEU 970 ? A LEU 970 
504  1 Y 1 A GLN 971 ? A GLN 971 
505  1 Y 1 A GLY 972 ? A GLY 972 
506  1 Y 1 A PRO 973 ? A PRO 973 
507  1 Y 1 A SER 974 ? A SER 974 
508  1 Y 1 A LEU 975 ? A LEU 975 
509  1 Y 1 A ARG 976 ? A ARG 976 
510  1 Y 1 A SER 977 ? A SER 977 
511  1 Y 1 A THR 978 ? A THR 978 
512  1 Y 1 A ASP 979 ? A ASP 979 
513  1 Y 1 A GLU 980 ? A GLU 980 
514  1 Y 1 A GLU 981 ? A GLU 981 
515  1 Y 1 A ASP 982 ? A ASP 982 
516  1 Y 1 A GLU 983 ? A GLU 983 
517  1 Y 1 A ASP 984 ? A ASP 984 
518  1 Y 1 A GLU 985 ? A GLU 985 
519  1 Y 1 A LEU 986 ? A LEU 986 
520  1 Y 1 A ILE 987 ? A ILE 987 
521  1 Y 1 A LEU 988 ? A LEU 988 
522  1 Y 1 B MET 1   ? B MET 1   
523  1 Y 1 B GLU 2   ? B GLU 2   
524  1 Y 1 B GLN 3   ? B GLN 3   
525  1 Y 1 B SER 4   ? B SER 4   
526  1 Y 1 B ARG 5   ? B ARG 5   
527  1 Y 1 B SER 6   ? B SER 6   
528  1 Y 1 B GLN 7   ? B GLN 7   
529  1 Y 1 B GLN 8   ? B GLN 8   
530  1 Y 1 B ARG 9   ? B ARG 9   
531  1 Y 1 B GLY 10  ? B GLY 10  
532  1 Y 1 B GLY 11  ? B GLY 11  
533  1 Y 1 B GLU 12  ? B GLU 12  
534  1 Y 1 B GLN 13  ? B GLN 13  
535  1 Y 1 B SER 14  ? B SER 14  
536  1 Y 1 B TRP 15  ? B TRP 15  
537  1 Y 1 B TRP 16  ? B TRP 16  
538  1 Y 1 B GLY 17  ? B GLY 17  
539  1 Y 1 B SER 18  ? B SER 18  
540  1 Y 1 B ASP 19  ? B ASP 19  
541  1 Y 1 B PRO 20  ? B PRO 20  
542  1 Y 1 B GLN 21  ? B GLN 21  
543  1 Y 1 B TYR 22  ? B TYR 22  
544  1 Y 1 B GLN 23  ? B GLN 23  
545  1 Y 1 B TYR 24  ? B TYR 24  
546  1 Y 1 B MET 25  ? B MET 25  
547  1 Y 1 B PRO 26  ? B PRO 26  
548  1 Y 1 B PHE 27  ? B PHE 27  
549  1 Y 1 B GLU 28  ? B GLU 28  
550  1 Y 1 B HIS 29  ? B HIS 29  
551  1 Y 1 B CYS 30  ? B CYS 30  
552  1 Y 1 B THR 31  ? B THR 31  
553  1 Y 1 B SER 32  ? B SER 32  
554  1 Y 1 B TYR 33  ? B TYR 33  
555  1 Y 1 B GLY 34  ? B GLY 34  
556  1 Y 1 B LEU 35  ? B LEU 35  
557  1 Y 1 B PRO 36  ? B PRO 36  
558  1 Y 1 B SER 37  ? B SER 37  
559  1 Y 1 B GLU 38  ? B GLU 38  
560  1 Y 1 B ASN 39  ? B ASN 39  
561  1 Y 1 B GLY 40  ? B GLY 40  
562  1 Y 1 B GLY 41  ? B GLY 41  
563  1 Y 1 B LEU 42  ? B LEU 42  
564  1 Y 1 B GLN 43  ? B GLN 43  
565  1 Y 1 B HIS 44  ? B HIS 44  
566  1 Y 1 B ARG 45  ? B ARG 45  
567  1 Y 1 B LEU 46  ? B LEU 46  
568  1 Y 1 B ARG 47  ? B ARG 47  
569  1 Y 1 B LYS 48  ? B LYS 48  
570  1 Y 1 B ASP 49  ? B ASP 49  
571  1 Y 1 B ALA 50  ? B ALA 50  
572  1 Y 1 B GLY 51  ? B GLY 51  
573  1 Y 1 B PRO 52  ? B PRO 52  
574  1 Y 1 B ARG 53  ? B ARG 53  
575  1 Y 1 B HIS 54  ? B HIS 54  
576  1 Y 1 B ASN 55  ? B ASN 55  
577  1 Y 1 B VAL 56  ? B VAL 56  
578  1 Y 1 B HIS 57  ? B HIS 57  
579  1 Y 1 B PRO 58  ? B PRO 58  
580  1 Y 1 B THR 59  ? B THR 59  
581  1 Y 1 B GLN 60  ? B GLN 60  
582  1 Y 1 B ILE 61  ? B ILE 61  
583  1 Y 1 B TYR 62  ? B TYR 62  
584  1 Y 1 B GLY 63  ? B GLY 63  
585  1 Y 1 B HIS 64  ? B HIS 64  
586  1 Y 1 B HIS 65  ? B HIS 65  
587  1 Y 1 B LYS 66  ? B LYS 66  
588  1 Y 1 B GLU 67  ? B GLU 67  
589  1 Y 1 B GLN 68  ? B GLN 68  
590  1 Y 1 B PHE 69  ? B PHE 69  
591  1 Y 1 B SER 70  ? B SER 70  
592  1 Y 1 B ASP 71  ? B ASP 71  
593  1 Y 1 B ARG 72  ? B ARG 72  
594  1 Y 1 B GLU 73  ? B GLU 73  
595  1 Y 1 B GLN 74  ? B GLN 74  
596  1 Y 1 B ASP 75  ? B ASP 75  
597  1 Y 1 B ILE 76  ? B ILE 76  
598  1 Y 1 B GLY 77  ? B GLY 77  
599  1 Y 1 B MET 78  ? B MET 78  
600  1 Y 1 B PRO 79  ? B PRO 79  
601  1 Y 1 B LYS 80  ? B LYS 80  
602  1 Y 1 B LYS 81  ? B LYS 81  
603  1 Y 1 B THR 82  ? B THR 82  
604  1 Y 1 B GLY 83  ? B GLY 83  
605  1 Y 1 B SER 84  ? B SER 84  
606  1 Y 1 B SER 85  ? B SER 85  
607  1 Y 1 B SER 86  ? B SER 86  
608  1 Y 1 B THR 87  ? B THR 87  
609  1 Y 1 B VAL 88  ? B VAL 88  
610  1 Y 1 B ASP 89  ? B ASP 89  
611  1 Y 1 B SER 90  ? B SER 90  
612  1 Y 1 B LYS 91  ? B LYS 91  
613  1 Y 1 B ASP 92  ? B ASP 92  
614  1 Y 1 B GLU 93  ? B GLU 93  
615  1 Y 1 B ASP 94  ? B ASP 94  
616  1 Y 1 B HIS 95  ? B HIS 95  
617  1 Y 1 B TYR 96  ? B TYR 96  
618  1 Y 1 B SER 97  ? B SER 97  
619  1 Y 1 B LYS 98  ? B LYS 98  
620  1 Y 1 B CYS 99  ? B CYS 99  
621  1 Y 1 B GLN 100 ? B GLN 100 
622  1 Y 1 B ASP 101 ? B ASP 101 
623  1 Y 1 B CYS 102 ? B CYS 102 
624  1 Y 1 B ILE 103 ? B ILE 103 
625  1 Y 1 B HIS 104 ? B HIS 104 
626  1 Y 1 B ARG 105 ? B ARG 105 
627  1 Y 1 B LEU 106 ? B LEU 106 
628  1 Y 1 B GLY 107 ? B GLY 107 
629  1 Y 1 B GLN 108 ? B GLN 108 
630  1 Y 1 B VAL 109 ? B VAL 109 
631  1 Y 1 B VAL 110 ? B VAL 110 
632  1 Y 1 B ARG 111 ? B ARG 111 
633  1 Y 1 B ARG 112 ? B ARG 112 
634  1 Y 1 B LYS 113 ? B LYS 113 
635  1 Y 1 B LEU 114 ? B LEU 114 
636  1 Y 1 B CYS 254 ? B CYS 254 
637  1 Y 1 B GLY 255 ? B GLY 255 
638  1 Y 1 B VAL 256 ? B VAL 256 
639  1 Y 1 B TYR 257 ? B TYR 257 
640  1 Y 1 B GLU 258 ? B GLU 258 
641  1 Y 1 B GLN 259 ? B GLN 259 
642  1 Y 1 B PRO 260 ? B PRO 260 
643  1 Y 1 B TYR 261 ? B TYR 261 
644  1 Y 1 B LEU 590 ? B LEU 590 
645  1 Y 1 B PRO 591 ? B PRO 591 
646  1 Y 1 B ASP 592 ? B ASP 592 
647  1 Y 1 B LEU 593 ? B LEU 593 
648  1 Y 1 B GLY 594 ? B GLY 594 
649  1 Y 1 B TRP 595 ? B TRP 595 
650  1 Y 1 B ASN 596 ? B ASN 596 
651  1 Y 1 B GLN 597 ? B GLN 597 
652  1 Y 1 B LEU 598 ? B LEU 598 
653  1 Y 1 B SER 599 ? B SER 599 
654  1 Y 1 B LYS 600 ? B LYS 600 
655  1 Y 1 B TYR 601 ? B TYR 601 
656  1 Y 1 B THR 602 ? B THR 602 
657  1 Y 1 B ILE 603 ? B ILE 603 
658  1 Y 1 B PHE 604 ? B PHE 604 
659  1 Y 1 B VAL 605 ? B VAL 605 
660  1 Y 1 B GLU 606 ? B GLU 606 
661  1 Y 1 B ASP 607 ? B ASP 607 
662  1 Y 1 B ILE 608 ? B ILE 608 
663  1 Y 1 B MET 609 ? B MET 609 
664  1 Y 1 B VAL 610 ? B VAL 610 
665  1 Y 1 B ARG 611 ? B ARG 611 
666  1 Y 1 B ASP 612 ? B ASP 612 
667  1 Y 1 B VAL 613 ? B VAL 613 
668  1 Y 1 B LYS 614 ? B LYS 614 
669  1 Y 1 B PHE 615 ? B PHE 615 
670  1 Y 1 B VAL 616 ? B VAL 616 
671  1 Y 1 B SER 617 ? B SER 617 
672  1 Y 1 B ALA 618 ? B ALA 618 
673  1 Y 1 B SER 619 ? B SER 619 
674  1 Y 1 B TYR 620 ? B TYR 620 
675  1 Y 1 B THR 621 ? B THR 621 
676  1 Y 1 B TYR 622 ? B TYR 622 
677  1 Y 1 B GLY 623 ? B GLY 623 
678  1 Y 1 B GLU 624 ? B GLU 624 
679  1 Y 1 B LEU 625 ? B LEU 625 
680  1 Y 1 B ARG 626 ? B ARG 626 
681  1 Y 1 B THR 627 ? B THR 627 
682  1 Y 1 B LEU 628 ? B LEU 628 
683  1 Y 1 B LEU 629 ? B LEU 629 
684  1 Y 1 B GLN 630 ? B GLN 630 
685  1 Y 1 B THR 631 ? B THR 631 
686  1 Y 1 B THR 632 ? B THR 632 
687  1 Y 1 B THR 633 ? B THR 633 
688  1 Y 1 B VAL 634 ? B VAL 634 
689  1 Y 1 B LYS 635 ? B LYS 635 
690  1 Y 1 B THR 636 ? B THR 636 
691  1 Y 1 B LEU 637 ? B LEU 637 
692  1 Y 1 B PRO 638 ? B PRO 638 
693  1 Y 1 B LEU 639 ? B LEU 639 
694  1 Y 1 B VAL 640 ? B VAL 640 
695  1 Y 1 B ASP 641 ? B ASP 641 
696  1 Y 1 B SER 642 ? B SER 642 
697  1 Y 1 B LYS 643 ? B LYS 643 
698  1 Y 1 B ASP 644 ? B ASP 644 
699  1 Y 1 B SER 645 ? B SER 645 
700  1 Y 1 B MET 646 ? B MET 646 
701  1 Y 1 B ILE 647 ? B ILE 647 
702  1 Y 1 B LEU 648 ? B LEU 648 
703  1 Y 1 B LEU 649 ? B LEU 649 
704  1 Y 1 B GLY 650 ? B GLY 650 
705  1 Y 1 B SER 651 ? B SER 651 
706  1 Y 1 B VAL 652 ? B VAL 652 
707  1 Y 1 B GLU 653 ? B GLU 653 
708  1 Y 1 B ARG 654 ? B ARG 654 
709  1 Y 1 B SER 655 ? B SER 655 
710  1 Y 1 B GLU 656 ? B GLU 656 
711  1 Y 1 B LEU 657 ? B LEU 657 
712  1 Y 1 B GLN 658 ? B GLN 658 
713  1 Y 1 B ALA 659 ? B ALA 659 
714  1 Y 1 B LEU 660 ? B LEU 660 
715  1 Y 1 B LEU 661 ? B LEU 661 
716  1 Y 1 B GLN 662 ? B GLN 662 
717  1 Y 1 B ARG 663 ? B ARG 663 
718  1 Y 1 B HIS 664 ? B HIS 664 
719  1 Y 1 B LEU 665 ? B LEU 665 
720  1 Y 1 B CYS 666 ? B CYS 666 
721  1 Y 1 B PRO 667 ? B PRO 667 
722  1 Y 1 B GLU 668 ? B GLU 668 
723  1 Y 1 B ARG 669 ? B ARG 669 
724  1 Y 1 B ARG 670 ? B ARG 670 
725  1 Y 1 B LEU 671 ? B LEU 671 
726  1 Y 1 B ARG 672 ? B ARG 672 
727  1 Y 1 B ALA 673 ? B ALA 673 
728  1 Y 1 B ALA 674 ? B ALA 674 
729  1 Y 1 B GLN 675 ? B GLN 675 
730  1 Y 1 B GLU 676 ? B GLU 676 
731  1 Y 1 B MET 677 ? B MET 677 
732  1 Y 1 B ALA 678 ? B ALA 678 
733  1 Y 1 B ARG 679 ? B ARG 679 
734  1 Y 1 B LYS 680 ? B LYS 680 
735  1 Y 1 B LEU 681 ? B LEU 681 
736  1 Y 1 B SER 682 ? B SER 682 
737  1 Y 1 B GLU 683 ? B GLU 683 
738  1 Y 1 B LEU 684 ? B LEU 684 
739  1 Y 1 B PRO 685 ? B PRO 685 
740  1 Y 1 B TYR 686 ? B TYR 686 
741  1 Y 1 B ASP 687 ? B ASP 687 
742  1 Y 1 B GLY 688 ? B GLY 688 
743  1 Y 1 B LYS 689 ? B LYS 689 
744  1 Y 1 B ALA 690 ? B ALA 690 
745  1 Y 1 B ARG 691 ? B ARG 691 
746  1 Y 1 B LEU 692 ? B LEU 692 
747  1 Y 1 B ALA 693 ? B ALA 693 
748  1 Y 1 B GLY 694 ? B GLY 694 
749  1 Y 1 B GLU 695 ? B GLU 695 
750  1 Y 1 B GLY 696 ? B GLY 696 
751  1 Y 1 B LEU 697 ? B LEU 697 
752  1 Y 1 B PRO 698 ? B PRO 698 
753  1 Y 1 B GLY 699 ? B GLY 699 
754  1 Y 1 B ALA 700 ? B ALA 700 
755  1 Y 1 B PRO 701 ? B PRO 701 
756  1 Y 1 B PRO 702 ? B PRO 702 
757  1 Y 1 B GLY 703 ? B GLY 703 
758  1 Y 1 B ARG 704 ? B ARG 704 
759  1 Y 1 B PRO 705 ? B PRO 705 
760  1 Y 1 B GLU 706 ? B GLU 706 
761  1 Y 1 B SER 707 ? B SER 707 
762  1 Y 1 B PHE 708 ? B PHE 708 
763  1 Y 1 B ALA 709 ? B ALA 709 
764  1 Y 1 B PHE 710 ? B PHE 710 
765  1 Y 1 B VAL 711 ? B VAL 711 
766  1 Y 1 B ASP 712 ? B ASP 712 
767  1 Y 1 B GLU 713 ? B GLU 713 
768  1 Y 1 B ASP 714 ? B ASP 714 
769  1 Y 1 B GLU 715 ? B GLU 715 
770  1 Y 1 B ASP 716 ? B ASP 716 
771  1 Y 1 B GLU 717 ? B GLU 717 
772  1 Y 1 B ASP 718 ? B ASP 718 
773  1 Y 1 B LEU 719 ? B LEU 719 
774  1 Y 1 B SER 720 ? B SER 720 
775  1 Y 1 B GLY 721 ? B GLY 721 
776  1 Y 1 B LYS 722 ? B LYS 722 
777  1 Y 1 B SER 723 ? B SER 723 
778  1 Y 1 B GLU 724 ? B GLU 724 
779  1 Y 1 B LEU 725 ? B LEU 725 
780  1 Y 1 B PRO 726 ? B PRO 726 
781  1 Y 1 B PRO 727 ? B PRO 727 
782  1 Y 1 B SER 728 ? B SER 728 
783  1 Y 1 B LEU 729 ? B LEU 729 
784  1 Y 1 B ALA 730 ? B ALA 730 
785  1 Y 1 B LEU 731 ? B LEU 731 
786  1 Y 1 B HIS 732 ? B HIS 732 
787  1 Y 1 B PRO 733 ? B PRO 733 
788  1 Y 1 B SER 734 ? B SER 734 
789  1 Y 1 B THR 735 ? B THR 735 
790  1 Y 1 B THR 736 ? B THR 736 
791  1 Y 1 B ALA 737 ? B ALA 737 
792  1 Y 1 B PRO 738 ? B PRO 738 
793  1 Y 1 B LEU 739 ? B LEU 739 
794  1 Y 1 B SER 740 ? B SER 740 
795  1 Y 1 B PRO 741 ? B PRO 741 
796  1 Y 1 B GLU 742 ? B GLU 742 
797  1 Y 1 B GLU 743 ? B GLU 743 
798  1 Y 1 B PRO 744 ? B PRO 744 
799  1 Y 1 B ASN 745 ? B ASN 745 
800  1 Y 1 B GLY 746 ? B GLY 746 
801  1 Y 1 B PRO 747 ? B PRO 747 
802  1 Y 1 B LEU 748 ? B LEU 748 
803  1 Y 1 B PRO 749 ? B PRO 749 
804  1 Y 1 B GLY 750 ? B GLY 750 
805  1 Y 1 B HIS 751 ? B HIS 751 
806  1 Y 1 B LYS 752 ? B LYS 752 
807  1 Y 1 B GLN 753 ? B GLN 753 
808  1 Y 1 B GLN 754 ? B GLN 754 
809  1 Y 1 B PRO 755 ? B PRO 755 
810  1 Y 1 B GLU 756 ? B GLU 756 
811  1 Y 1 B ALA 757 ? B ALA 757 
812  1 Y 1 B PRO 758 ? B PRO 758 
813  1 Y 1 B GLU 759 ? B GLU 759 
814  1 Y 1 B PRO 760 ? B PRO 760 
815  1 Y 1 B ALA 761 ? B ALA 761 
816  1 Y 1 B GLY 762 ? B GLY 762 
817  1 Y 1 B GLN 763 ? B GLN 763 
818  1 Y 1 B ARG 764 ? B ARG 764 
819  1 Y 1 B PRO 765 ? B PRO 765 
820  1 Y 1 B SER 766 ? B SER 766 
821  1 Y 1 B ILE 767 ? B ILE 767 
822  1 Y 1 B PHE 768 ? B PHE 768 
823  1 Y 1 B GLN 769 ? B GLN 769 
824  1 Y 1 B SER 770 ? B SER 770 
825  1 Y 1 B LEU 771 ? B LEU 771 
826  1 Y 1 B LEU 772 ? B LEU 772 
827  1 Y 1 B HIS 773 ? B HIS 773 
828  1 Y 1 B CYS 774 ? B CYS 774 
829  1 Y 1 B LEU 775 ? B LEU 775 
830  1 Y 1 B LEU 776 ? B LEU 776 
831  1 Y 1 B GLY 777 ? B GLY 777 
832  1 Y 1 B ARG 778 ? B ARG 778 
833  1 Y 1 B ALA 779 ? B ALA 779 
834  1 Y 1 B ARG 780 ? B ARG 780 
835  1 Y 1 B PRO 781 ? B PRO 781 
836  1 Y 1 B THR 782 ? B THR 782 
837  1 Y 1 B LYS 783 ? B LYS 783 
838  1 Y 1 B LYS 784 ? B LYS 784 
839  1 Y 1 B LYS 785 ? B LYS 785 
840  1 Y 1 B THR 786 ? B THR 786 
841  1 Y 1 B THR 787 ? B THR 787 
842  1 Y 1 B GLN 788 ? B GLN 788 
843  1 Y 1 B ASP 789 ? B ASP 789 
844  1 Y 1 B SER 790 ? B SER 790 
845  1 Y 1 B THR 791 ? B THR 791 
846  1 Y 1 B ASP 792 ? B ASP 792 
847  1 Y 1 B LEU 793 ? B LEU 793 
848  1 Y 1 B VAL 794 ? B VAL 794 
849  1 Y 1 B ASP 795 ? B ASP 795 
850  1 Y 1 B ASN 796 ? B ASN 796 
851  1 Y 1 B MET 797 ? B MET 797 
852  1 Y 1 B SER 798 ? B SER 798 
853  1 Y 1 B PRO 799 ? B PRO 799 
854  1 Y 1 B GLU 800 ? B GLU 800 
855  1 Y 1 B GLU 801 ? B GLU 801 
856  1 Y 1 B ILE 802 ? B ILE 802 
857  1 Y 1 B GLU 803 ? B GLU 803 
858  1 Y 1 B ALA 804 ? B ALA 804 
859  1 Y 1 B TRP 805 ? B TRP 805 
860  1 Y 1 B GLU 806 ? B GLU 806 
861  1 Y 1 B GLN 807 ? B GLN 807 
862  1 Y 1 B GLU 808 ? B GLU 808 
863  1 Y 1 B GLN 809 ? B GLN 809 
864  1 Y 1 B LEU 810 ? B LEU 810 
865  1 Y 1 B SER 811 ? B SER 811 
866  1 Y 1 B GLN 812 ? B GLN 812 
867  1 Y 1 B PRO 813 ? B PRO 813 
868  1 Y 1 B VAL 814 ? B VAL 814 
869  1 Y 1 B CYS 815 ? B CYS 815 
870  1 Y 1 B PHE 816 ? B PHE 816 
871  1 Y 1 B ASP 817 ? B ASP 817 
872  1 Y 1 B SER 818 ? B SER 818 
873  1 Y 1 B CYS 819 ? B CYS 819 
874  1 Y 1 B CYS 820 ? B CYS 820 
875  1 Y 1 B ILE 821 ? B ILE 821 
876  1 Y 1 B ASP 822 ? B ASP 822 
877  1 Y 1 B GLN 823 ? B GLN 823 
878  1 Y 1 B SER 824 ? B SER 824 
879  1 Y 1 B PRO 825 ? B PRO 825 
880  1 Y 1 B PHE 826 ? B PHE 826 
881  1 Y 1 B GLN 827 ? B GLN 827 
882  1 Y 1 B LEU 828 ? B LEU 828 
883  1 Y 1 B VAL 829 ? B VAL 829 
884  1 Y 1 B GLU 830 ? B GLU 830 
885  1 Y 1 B GLN 831 ? B GLN 831 
886  1 Y 1 B THR 832 ? B THR 832 
887  1 Y 1 B THR 833 ? B THR 833 
888  1 Y 1 B LEU 834 ? B LEU 834 
889  1 Y 1 B HIS 835 ? B HIS 835 
890  1 Y 1 B LYS 836 ? B LYS 836 
891  1 Y 1 B THR 837 ? B THR 837 
892  1 Y 1 B HIS 838 ? B HIS 838 
893  1 Y 1 B THR 839 ? B THR 839 
894  1 Y 1 B LEU 840 ? B LEU 840 
895  1 Y 1 B PHE 841 ? B PHE 841 
896  1 Y 1 B SER 842 ? B SER 842 
897  1 Y 1 B LEU 843 ? B LEU 843 
898  1 Y 1 B LEU 844 ? B LEU 844 
899  1 Y 1 B GLY 845 ? B GLY 845 
900  1 Y 1 B LEU 846 ? B LEU 846 
901  1 Y 1 B HIS 847 ? B HIS 847 
902  1 Y 1 B LEU 848 ? B LEU 848 
903  1 Y 1 B ALA 849 ? B ALA 849 
904  1 Y 1 B TYR 850 ? B TYR 850 
905  1 Y 1 B VAL 851 ? B VAL 851 
906  1 Y 1 B THR 852 ? B THR 852 
907  1 Y 1 B SER 853 ? B SER 853 
908  1 Y 1 B MET 854 ? B MET 854 
909  1 Y 1 B GLY 855 ? B GLY 855 
910  1 Y 1 B LYS 856 ? B LYS 856 
911  1 Y 1 B LEU 857 ? B LEU 857 
912  1 Y 1 B ARG 858 ? B ARG 858 
913  1 Y 1 B GLY 859 ? B GLY 859 
914  1 Y 1 B VAL 860 ? B VAL 860 
915  1 Y 1 B LEU 861 ? B LEU 861 
916  1 Y 1 B ALA 862 ? B ALA 862 
917  1 Y 1 B LEU 863 ? B LEU 863 
918  1 Y 1 B GLU 864 ? B GLU 864 
919  1 Y 1 B GLU 865 ? B GLU 865 
920  1 Y 1 B LEU 866 ? B LEU 866 
921  1 Y 1 B GLN 867 ? B GLN 867 
922  1 Y 1 B LYS 868 ? B LYS 868 
923  1 Y 1 B ALA 869 ? B ALA 869 
924  1 Y 1 B ILE 870 ? B ILE 870 
925  1 Y 1 B GLU 871 ? B GLU 871 
926  1 Y 1 B GLY 872 ? B GLY 872 
927  1 Y 1 B HIS 873 ? B HIS 873 
928  1 Y 1 B THR 874 ? B THR 874 
929  1 Y 1 B LYS 875 ? B LYS 875 
930  1 Y 1 B SER 876 ? B SER 876 
931  1 Y 1 B GLY 877 ? B GLY 877 
932  1 Y 1 B VAL 878 ? B VAL 878 
933  1 Y 1 B GLN 879 ? B GLN 879 
934  1 Y 1 B LEU 880 ? B LEU 880 
935  1 Y 1 B ARG 881 ? B ARG 881 
936  1 Y 1 B PRO 882 ? B PRO 882 
937  1 Y 1 B PRO 883 ? B PRO 883 
938  1 Y 1 B LEU 884 ? B LEU 884 
939  1 Y 1 B ALA 885 ? B ALA 885 
940  1 Y 1 B SER 886 ? B SER 886 
941  1 Y 1 B PHE 887 ? B PHE 887 
942  1 Y 1 B ARG 888 ? B ARG 888 
943  1 Y 1 B ASN 889 ? B ASN 889 
944  1 Y 1 B THR 890 ? B THR 890 
945  1 Y 1 B THR 891 ? B THR 891 
946  1 Y 1 B SER 892 ? B SER 892 
947  1 Y 1 B THR 893 ? B THR 893 
948  1 Y 1 B ARG 894 ? B ARG 894 
949  1 Y 1 B LYS 895 ? B LYS 895 
950  1 Y 1 B SER 896 ? B SER 896 
951  1 Y 1 B THR 897 ? B THR 897 
952  1 Y 1 B GLY 898 ? B GLY 898 
953  1 Y 1 B ALA 899 ? B ALA 899 
954  1 Y 1 B PRO 900 ? B PRO 900 
955  1 Y 1 B PRO 901 ? B PRO 901 
956  1 Y 1 B SER 902 ? B SER 902 
957  1 Y 1 B SER 903 ? B SER 903 
958  1 Y 1 B ALA 904 ? B ALA 904 
959  1 Y 1 B GLU 905 ? B GLU 905 
960  1 Y 1 B ASN 906 ? B ASN 906 
961  1 Y 1 B TRP 907 ? B TRP 907 
962  1 Y 1 B ASN 908 ? B ASN 908 
963  1 Y 1 B LEU 909 ? B LEU 909 
964  1 Y 1 B PRO 910 ? B PRO 910 
965  1 Y 1 B GLU 911 ? B GLU 911 
966  1 Y 1 B ASP 912 ? B ASP 912 
967  1 Y 1 B ARG 913 ? B ARG 913 
968  1 Y 1 B PRO 914 ? B PRO 914 
969  1 Y 1 B GLY 915 ? B GLY 915 
970  1 Y 1 B ALA 916 ? B ALA 916 
971  1 Y 1 B THR 917 ? B THR 917 
972  1 Y 1 B GLY 918 ? B GLY 918 
973  1 Y 1 B THR 919 ? B THR 919 
974  1 Y 1 B GLY 920 ? B GLY 920 
975  1 Y 1 B ASP 921 ? B ASP 921 
976  1 Y 1 B VAL 922 ? B VAL 922 
977  1 Y 1 B ILE 923 ? B ILE 923 
978  1 Y 1 B ALA 924 ? B ALA 924 
979  1 Y 1 B ALA 925 ? B ALA 925 
980  1 Y 1 B SER 926 ? B SER 926 
981  1 Y 1 B PRO 927 ? B PRO 927 
982  1 Y 1 B GLU 928 ? B GLU 928 
983  1 Y 1 B THR 929 ? B THR 929 
984  1 Y 1 B PRO 930 ? B PRO 930 
985  1 Y 1 B VAL 931 ? B VAL 931 
986  1 Y 1 B PRO 932 ? B PRO 932 
987  1 Y 1 B SER 933 ? B SER 933 
988  1 Y 1 B PRO 934 ? B PRO 934 
989  1 Y 1 B SER 935 ? B SER 935 
990  1 Y 1 B PRO 936 ? B PRO 936 
991  1 Y 1 B GLU 937 ? B GLU 937 
992  1 Y 1 B PRO 938 ? B PRO 938 
993  1 Y 1 B PRO 939 ? B PRO 939 
994  1 Y 1 B LEU 940 ? B LEU 940 
995  1 Y 1 B SER 941 ? B SER 941 
996  1 Y 1 B LEU 942 ? B LEU 942 
997  1 Y 1 B ALA 943 ? B ALA 943 
998  1 Y 1 B PRO 944 ? B PRO 944 
999  1 Y 1 B GLY 945 ? B GLY 945 
1000 1 Y 1 B LYS 946 ? B LYS 946 
1001 1 Y 1 B VAL 947 ? B VAL 947 
1002 1 Y 1 B GLU 948 ? B GLU 948 
1003 1 Y 1 B GLY 949 ? B GLY 949 
1004 1 Y 1 B GLU 950 ? B GLU 950 
1005 1 Y 1 B LEU 951 ? B LEU 951 
1006 1 Y 1 B GLU 952 ? B GLU 952 
1007 1 Y 1 B GLU 953 ? B GLU 953 
1008 1 Y 1 B LEU 954 ? B LEU 954 
1009 1 Y 1 B GLU 955 ? B GLU 955 
1010 1 Y 1 B LEU 956 ? B LEU 956 
1011 1 Y 1 B VAL 957 ? B VAL 957 
1012 1 Y 1 B GLU 958 ? B GLU 958 
1013 1 Y 1 B SER 959 ? B SER 959 
1014 1 Y 1 B PRO 960 ? B PRO 960 
1015 1 Y 1 B GLY 961 ? B GLY 961 
1016 1 Y 1 B LEU 962 ? B LEU 962 
1017 1 Y 1 B GLU 963 ? B GLU 963 
1018 1 Y 1 B GLU 964 ? B GLU 964 
1019 1 Y 1 B GLU 965 ? B GLU 965 
1020 1 Y 1 B LEU 966 ? B LEU 966 
1021 1 Y 1 B ALA 967 ? B ALA 967 
1022 1 Y 1 B ASP 968 ? B ASP 968 
1023 1 Y 1 B ILE 969 ? B ILE 969 
1024 1 Y 1 B LEU 970 ? B LEU 970 
1025 1 Y 1 B GLN 971 ? B GLN 971 
1026 1 Y 1 B GLY 972 ? B GLY 972 
1027 1 Y 1 B PRO 973 ? B PRO 973 
1028 1 Y 1 B SER 974 ? B SER 974 
1029 1 Y 1 B LEU 975 ? B LEU 975 
1030 1 Y 1 B ARG 976 ? B ARG 976 
1031 1 Y 1 B SER 977 ? B SER 977 
1032 1 Y 1 B THR 978 ? B THR 978 
1033 1 Y 1 B ASP 979 ? B ASP 979 
1034 1 Y 1 B GLU 980 ? B GLU 980 
1035 1 Y 1 B GLU 981 ? B GLU 981 
1036 1 Y 1 B ASP 982 ? B ASP 982 
1037 1 Y 1 B GLU 983 ? B GLU 983 
1038 1 Y 1 B ASP 984 ? B ASP 984 
1039 1 Y 1 B GLU 985 ? B GLU 985 
1040 1 Y 1 B LEU 986 ? B LEU 986 
1041 1 Y 1 B ILE 987 ? B ILE 987 
1042 1 Y 1 B LEU 988 ? B LEU 988 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SCN S    S N N 287 
SCN C    C N N 288 
SCN N    N N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SCN S   C    sing N N 275 
SCN C   N    trip N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-10-29 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8WXJ 
_em_admin.last_update        2024-11-06 
_em_admin.map_release_date   2024-11-06 
_em_admin.title              'human CLC-1 D136G closed state' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8WXJ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLY A 1 115 ? 105.347 134.711 115.543 1.00 307.19 ?  115  GLY A N   1 
ATOM   2    C CA  . GLY A 1 115 ? 104.245 134.401 114.652 1.00 307.19 ?  115  GLY A CA  1 
ATOM   3    C C   . GLY A 1 115 ? 103.748 132.990 114.857 1.00 307.19 ?  115  GLY A C   1 
ATOM   4    O O   . GLY A 1 115 ? 103.488 132.584 115.985 1.00 307.19 ?  115  GLY A O   1 
ATOM   5    N N   . GLU A 1 116 ? 103.622 132.233 113.773 1.00 330.29 ?  116  GLU A N   1 
ATOM   6    C CA  . GLU A 1 116 ? 103.190 130.845 113.879 1.00 330.29 ?  116  GLU A CA  1 
ATOM   7    C C   . GLU A 1 116 ? 104.301 129.976 114.442 1.00 330.29 ?  116  GLU A C   1 
ATOM   8    O O   . GLU A 1 116 ? 104.036 128.981 115.112 1.00 330.29 ?  116  GLU A O   1 
ATOM   9    C CB  . GLU A 1 116 ? 102.741 130.310 112.522 1.00 330.29 ?  116  GLU A CB  1 
ATOM   10   C CG  . GLU A 1 116 ? 101.539 129.385 112.598 1.00 330.29 ?  116  GLU A CG  1 
ATOM   11   C CD  . GLU A 1 116 ? 101.706 128.145 111.745 1.00 330.29 ?  116  GLU A CD  1 
ATOM   12   O OE1 . GLU A 1 116 ? 102.651 127.368 111.998 1.00 330.29 ?  116  GLU A OE1 1 
ATOM   13   O OE2 . GLU A 1 116 ? 100.890 127.949 110.822 1.00 330.29 -1 116  GLU A OE2 1 
ATOM   14   N N   . ASP A 1 117 ? 105.547 130.351 114.178 1.00 314.50 ?  117  ASP A N   1 
ATOM   15   C CA  . ASP A 1 117 ? 106.672 129.599 114.712 1.00 314.50 ?  117  ASP A CA  1 
ATOM   16   C C   . ASP A 1 117 ? 106.703 129.669 116.231 1.00 314.50 ?  117  ASP A C   1 
ATOM   17   O O   . ASP A 1 117 ? 107.016 128.685 116.879 1.00 314.50 ?  117  ASP A O   1 
ATOM   18   C CB  . ASP A 1 117 ? 107.997 130.075 114.109 1.00 314.50 ?  117  ASP A CB  1 
ATOM   19   C CG  . ASP A 1 117 ? 108.398 131.460 114.581 1.00 314.50 ?  117  ASP A CG  1 
ATOM   20   O OD1 . ASP A 1 117 ? 107.655 132.425 114.303 1.00 314.50 ?  117  ASP A OD1 1 
ATOM   21   O OD2 . ASP A 1 117 ? 109.456 131.582 115.234 1.00 314.50 -1 117  ASP A OD2 1 
ATOM   22   N N   . GLY A 1 118 ? 106.359 130.816 116.804 1.00 305.92 ?  118  GLY A N   1 
ATOM   23   C CA  . GLY A 1 118 ? 106.323 130.946 118.249 1.00 305.92 ?  118  GLY A CA  1 
ATOM   24   C C   . GLY A 1 118 ? 105.322 129.991 118.854 1.00 305.92 ?  118  GLY A C   1 
ATOM   25   O O   . GLY A 1 118 ? 105.603 129.359 119.868 1.00 305.92 ?  118  GLY A O   1 
ATOM   26   N N   . ILE A 1 119 ? 104.152 129.874 118.236 1.00 303.10 ?  119  ILE A N   1 
ATOM   27   C CA  . ILE A 1 119 ? 103.146 128.937 118.720 1.00 303.10 ?  119  ILE A CA  1 
ATOM   28   C C   . ILE A 1 119 ? 103.662 127.517 118.582 1.00 303.10 ?  119  ILE A C   1 
ATOM   29   O O   . ILE A 1 119 ? 103.491 126.707 119.483 1.00 303.10 ?  119  ILE A O   1 
ATOM   30   C CB  . ILE A 1 119 ? 101.820 129.076 117.953 1.00 303.10 ?  119  ILE A CB  1 
ATOM   31   C CG1 . ILE A 1 119 ? 101.498 130.547 117.704 1.00 303.10 ?  119  ILE A CG1 1 
ATOM   32   C CG2 . ILE A 1 119 ? 100.685 128.419 118.722 1.00 303.10 ?  119  ILE A CG2 1 
ATOM   33   C CD1 . ILE A 1 119 ? 100.362 130.762 116.730 1.00 303.10 ?  119  ILE A CD1 1 
ATOM   34   N N   . PHE A 1 120 ? 104.305 127.214 117.461 1.00 314.42 ?  120  PHE A N   1 
ATOM   35   C CA  . PHE A 1 120 ? 104.871 125.887 117.261 1.00 314.42 ?  120  PHE A CA  1 
ATOM   36   C C   . PHE A 1 120 ? 105.841 125.547 118.381 1.00 314.42 ?  120  PHE A C   1 
ATOM   37   O O   . PHE A 1 120 ? 105.777 124.462 118.942 1.00 314.42 ?  120  PHE A O   1 
ATOM   38   C CB  . PHE A 1 120 ? 105.551 125.799 115.893 1.00 314.42 ?  120  PHE A CB  1 
ATOM   39   C CG  . PHE A 1 120 ? 106.461 124.616 115.734 1.00 314.42 ?  120  PHE A CG  1 
ATOM   40   C CD1 . PHE A 1 120 ? 105.944 123.339 115.618 1.00 314.42 ?  120  PHE A CD1 1 
ATOM   41   C CD2 . PHE A 1 120 ? 107.835 124.786 115.684 1.00 314.42 ?  120  PHE A CD2 1 
ATOM   42   C CE1 . PHE A 1 120 ? 106.780 122.252 115.468 1.00 314.42 ?  120  PHE A CE1 1 
ATOM   43   C CE2 . PHE A 1 120 ? 108.676 123.703 115.536 1.00 314.42 ?  120  PHE A CE2 1 
ATOM   44   C CZ  . PHE A 1 120 ? 108.147 122.435 115.427 1.00 314.42 ?  120  PHE A CZ  1 
ATOM   45   N N   . LEU A 1 121 ? 106.728 126.474 118.719 1.00 306.71 ?  121  LEU A N   1 
ATOM   46   C CA  . LEU A 1 121 ? 107.706 126.226 119.769 1.00 306.71 ?  121  LEU A CA  1 
ATOM   47   C C   . LEU A 1 121 ? 107.033 126.012 121.117 1.00 306.71 ?  121  LEU A C   1 
ATOM   48   O O   . LEU A 1 121 ? 107.399 125.105 121.857 1.00 306.71 ?  121  LEU A O   1 
ATOM   49   C CB  . LEU A 1 121 ? 108.712 127.374 119.855 1.00 306.71 ?  121  LEU A CB  1 
ATOM   50   C CG  . LEU A 1 121 ? 109.452 127.746 118.573 1.00 306.71 ?  121  LEU A CG  1 
ATOM   51   C CD1 . LEU A 1 121 ? 110.275 129.010 118.741 1.00 306.71 ?  121  LEU A CD1 1 
ATOM   52   C CD2 . LEU A 1 121 ? 110.302 126.601 118.062 1.00 306.71 ?  121  LEU A CD2 1 
ATOM   53   N N   . VAL A 1 122 ? 106.048 126.840 121.438 1.00 300.11 ?  122  VAL A N   1 
ATOM   54   C CA  . VAL A 1 122 ? 105.336 126.698 122.701 1.00 300.11 ?  122  VAL A CA  1 
ATOM   55   C C   . VAL A 1 122 ? 104.641 125.347 122.747 1.00 300.11 ?  122  VAL A C   1 
ATOM   56   O O   . VAL A 1 122 ? 104.764 124.614 123.724 1.00 300.11 ?  122  VAL A O   1 
ATOM   57   C CB  . VAL A 1 122 ? 104.328 127.848 122.910 1.00 300.11 ?  122  VAL A CB  1 
ATOM   58   C CG1 . VAL A 1 122 ? 103.191 127.435 123.833 1.00 300.11 ?  122  VAL A CG1 1 
ATOM   59   C CG2 . VAL A 1 122 ? 105.035 129.074 123.460 1.00 300.11 ?  122  VAL A CG2 1 
ATOM   60   N N   . LEU A 1 123 ? 103.939 124.996 121.679 1.00 294.58 ?  123  LEU A N   1 
ATOM   61   C CA  . LEU A 1 123 ? 103.231 123.729 121.638 1.00 294.58 ?  123  LEU A CA  1 
ATOM   62   C C   . LEU A 1 123 ? 104.204 122.577 121.755 1.00 294.58 ?  123  LEU A C   1 
ATOM   63   O O   . LEU A 1 123 ? 103.951 121.639 122.492 1.00 294.58 ?  123  LEU A O   1 
ATOM   64   C CB  . LEU A 1 123 ? 102.426 123.609 120.348 1.00 294.58 ?  123  LEU A CB  1 
ATOM   65   C CG  . LEU A 1 123 ? 100.904 123.678 120.473 1.00 294.58 ?  123  LEU A CG  1 
ATOM   66   C CD1 . LEU A 1 123 ? 100.388 122.546 121.346 1.00 294.58 ?  123  LEU A CD1 1 
ATOM   67   C CD2 . LEU A 1 123 ? 100.464 125.026 121.020 1.00 294.58 ?  123  LEU A CD2 1 
ATOM   68   N N   . LEU A 1 124 ? 105.319 122.645 121.036 1.00 286.31 ?  124  LEU A N   1 
ATOM   69   C CA  . LEU A 1 124 ? 106.333 121.601 121.109 1.00 286.31 ?  124  LEU A CA  1 
ATOM   70   C C   . LEU A 1 124 ? 106.771 121.386 122.540 1.00 286.31 ?  124  LEU A C   1 
ATOM   71   O O   . LEU A 1 124 ? 106.704 120.275 123.047 1.00 286.31 ?  124  LEU A O   1 
ATOM   72   C CB  . LEU A 1 124 ? 107.544 121.982 120.266 1.00 286.31 ?  124  LEU A CB  1 
ATOM   73   C CG  . LEU A 1 124 ? 107.817 121.137 119.028 1.00 286.31 ?  124  LEU A CG  1 
ATOM   74   C CD1 . LEU A 1 124 ? 109.312 120.969 118.833 1.00 286.31 ?  124  LEU A CD1 1 
ATOM   75   C CD2 . LEU A 1 124 ? 107.140 119.788 119.163 1.00 286.31 ?  124  LEU A CD2 1 
ATOM   76   N N   . GLY A 1 125 ? 107.219 122.448 123.195 1.00 272.55 ?  125  GLY A N   1 
ATOM   77   C CA  . GLY A 1 125 ? 107.660 122.343 124.570 1.00 272.55 ?  125  GLY A CA  1 
ATOM   78   C C   . GLY A 1 125 ? 106.599 121.766 125.473 1.00 272.55 ?  125  GLY A C   1 
ATOM   79   O O   . GLY A 1 125 ? 106.867 120.838 126.224 1.00 272.55 ?  125  GLY A O   1 
ATOM   80   N N   . LEU A 1 126 ? 105.390 122.302 125.401 1.00 275.46 ?  126  LEU A N   1 
ATOM   81   C CA  . LEU A 1 126 ? 104.304 121.815 126.233 1.00 275.46 ?  126  LEU A CA  1 
ATOM   82   C C   . LEU A 1 126 ? 104.039 120.347 125.972 1.00 275.46 ?  126  LEU A C   1 
ATOM   83   O O   . LEU A 1 126 ? 104.036 119.546 126.899 1.00 275.46 ?  126  LEU A O   1 
ATOM   84   C CB  . LEU A 1 126 ? 103.038 122.629 125.985 1.00 275.46 ?  126  LEU A CB  1 
ATOM   85   C CG  . LEU A 1 126 ? 101.722 122.100 126.551 1.00 275.46 ?  126  LEU A CG  1 
ATOM   86   C CD1 . LEU A 1 126 ? 101.415 122.754 127.888 1.00 275.46 ?  126  LEU A CD1 1 
ATOM   87   C CD2 . LEU A 1 126 ? 100.593 122.335 125.561 1.00 275.46 ?  126  LEU A CD2 1 
ATOM   88   N N   . LEU A 1 127 ? 103.832 119.983 124.713 1.00 310.34 ?  127  LEU A N   1 
ATOM   89   C CA  . LEU A 1 127 ? 103.519 118.602 124.379 1.00 310.34 ?  127  LEU A CA  1 
ATOM   90   C C   . LEU A 1 127 ? 104.611 117.662 124.836 1.00 310.34 ?  127  LEU A C   1 
ATOM   91   O O   . LEU A 1 127 ? 104.330 116.629 125.424 1.00 310.34 ?  127  LEU A O   1 
ATOM   92   C CB  . LEU A 1 127 ? 103.296 118.441 122.878 1.00 310.34 ?  127  LEU A CB  1 
ATOM   93   C CG  . LEU A 1 127 ? 101.877 118.696 122.366 1.00 310.34 ?  127  LEU A CG  1 
ATOM   94   C CD1 . LEU A 1 127 ? 101.503 117.667 121.312 1.00 310.34 ?  127  LEU A CD1 1 
ATOM   95   C CD2 . LEU A 1 127 ? 100.871 118.686 123.506 1.00 310.34 ?  127  LEU A CD2 1 
ATOM   96   N N   . MET A 1 128 ? 105.858 118.014 124.564 1.00 291.41 ?  128  MET A N   1 
ATOM   97   C CA  . MET A 1 128 ? 106.970 117.161 124.949 1.00 291.41 ?  128  MET A CA  1 
ATOM   98   C C   . MET A 1 128 ? 107.059 116.995 126.457 1.00 291.41 ?  128  MET A C   1 
ATOM   99   O O   . MET A 1 128 ? 107.244 115.888 126.933 1.00 291.41 ?  128  MET A O   1 
ATOM   100  C CB  . MET A 1 128 ? 108.283 117.689 124.385 1.00 291.41 ?  128  MET A CB  1 
ATOM   101  C CG  . MET A 1 128 ? 108.843 116.827 123.270 1.00 291.41 ?  128  MET A CG  1 
ATOM   102  S SD  . MET A 1 128 ? 108.005 115.237 123.150 1.00 291.41 ?  128  MET A SD  1 
ATOM   103  C CE  . MET A 1 128 ? 109.158 114.189 124.032 1.00 291.41 ?  128  MET A CE  1 
ATOM   104  N N   . ALA A 1 129 ? 106.930 118.082 127.208 1.00 293.14 ?  129  ALA A N   1 
ATOM   105  C CA  . ALA A 1 129 ? 106.958 117.997 128.652 1.00 293.14 ?  129  ALA A CA  1 
ATOM   106  C C   . ALA A 1 129 ? 105.884 117.049 129.136 1.00 293.14 ?  129  ALA A C   1 
ATOM   107  O O   . ALA A 1 129 ? 106.137 116.216 129.991 1.00 293.14 ?  129  ALA A O   1 
ATOM   108  C CB  . ALA A 1 129 ? 106.767 119.366 129.260 1.00 293.14 ?  129  ALA A CB  1 
ATOM   109  N N   . LEU A 1 130 ? 104.686 117.164 128.580 1.00 300.42 ?  130  LEU A N   1 
ATOM   110  C CA  . LEU A 1 130 ? 103.587 116.299 128.981 1.00 300.42 ?  130  LEU A CA  1 
ATOM   111  C C   . LEU A 1 130 ? 103.854 114.841 128.645 1.00 300.42 ?  130  LEU A C   1 
ATOM   112  O O   . LEU A 1 130 ? 103.688 113.976 129.495 1.00 300.42 ?  130  LEU A O   1 
ATOM   113  C CB  . LEU A 1 130 ? 102.286 116.762 128.331 1.00 300.42 ?  130  LEU A CB  1 
ATOM   114  C CG  . LEU A 1 130 ? 101.735 118.098 128.823 1.00 300.42 ?  130  LEU A CG  1 
ATOM   115  C CD1 . LEU A 1 130 ? 100.539 118.519 127.987 1.00 300.42 ?  130  LEU A CD1 1 
ATOM   116  C CD2 . LEU A 1 130 ? 101.370 118.020 130.297 1.00 300.42 ?  130  LEU A CD2 1 
ATOM   117  N N   . VAL A 1 131 ? 104.268 114.563 127.415 1.00 275.05 ?  131  VAL A N   1 
ATOM   118  C CA  . VAL A 1 131 ? 104.570 113.195 127.007 1.00 275.05 ?  131  VAL A CA  1 
ATOM   119  C C   . VAL A 1 131 ? 105.697 112.625 127.849 1.00 275.05 ?  131  VAL A C   1 
ATOM   120  O O   . VAL A 1 131 ? 105.584 111.525 128.373 1.00 275.05 ?  131  VAL A O   1 
ATOM   121  C CB  . VAL A 1 131 ? 104.934 113.125 125.511 1.00 275.05 ?  131  VAL A CB  1 
ATOM   122  C CG1 . VAL A 1 131 ? 105.481 111.757 125.141 1.00 275.05 ?  131  VAL A CG1 1 
ATOM   123  C CG2 . VAL A 1 131 ? 103.720 113.452 124.659 1.00 275.05 ?  131  VAL A CG2 1 
ATOM   124  N N   . SER A 1 132 ? 106.776 113.379 128.006 1.00 258.77 ?  132  SER A N   1 
ATOM   125  C CA  . SER A 1 132 ? 107.906 112.924 128.803 1.00 258.77 ?  132  SER A CA  1 
ATOM   126  C C   . SER A 1 132 ? 107.508 112.664 130.240 1.00 258.77 ?  132  SER A C   1 
ATOM   127  O O   . SER A 1 132 ? 107.912 111.666 130.824 1.00 258.77 ?  132  SER A O   1 
ATOM   128  C CB  . SER A 1 132 ? 109.029 113.953 128.765 1.00 258.77 ?  132  SER A CB  1 
ATOM   129  O OG  . SER A 1 132 ? 109.985 113.699 129.777 1.00 258.77 ?  132  SER A OG  1 
ATOM   130  N N   . TRP A 1 133 ? 106.720 113.560 130.818 1.00 271.73 ?  133  TRP A N   1 
ATOM   131  C CA  . TRP A 1 133 ? 106.275 113.381 132.186 1.00 271.73 ?  133  TRP A CA  1 
ATOM   132  C C   . TRP A 1 133 ? 105.451 112.120 132.293 1.00 271.73 ?  133  TRP A C   1 
ATOM   133  O O   . TRP A 1 133 ? 105.679 111.315 133.178 1.00 271.73 ?  133  TRP A O   1 
ATOM   134  C CB  . TRP A 1 133 ? 105.458 114.577 132.665 1.00 271.73 ?  133  TRP A CB  1 
ATOM   135  C CG  . TRP A 1 133 ? 105.125 114.520 134.117 1.00 271.73 ?  133  TRP A CG  1 
ATOM   136  C CD1 . TRP A 1 133 ? 105.902 114.945 135.152 1.00 271.73 ?  133  TRP A CD1 1 
ATOM   137  C CD2 . TRP A 1 133 ? 103.926 114.001 134.700 1.00 271.73 ?  133  TRP A CD2 1 
ATOM   138  N NE1 . TRP A 1 133 ? 105.260 114.723 136.345 1.00 271.73 ?  133  TRP A NE1 1 
ATOM   139  C CE2 . TRP A 1 133 ? 104.046 114.143 136.094 1.00 271.73 ?  133  TRP A CE2 1 
ATOM   140  C CE3 . TRP A 1 133 ? 102.764 113.427 134.178 1.00 271.73 ?  133  TRP A CE3 1 
ATOM   141  C CZ2 . TRP A 1 133 ? 103.049 113.735 136.971 1.00 271.73 ?  133  TRP A CZ2 1 
ATOM   142  C CZ3 . TRP A 1 133 ? 101.777 113.022 135.049 1.00 271.73 ?  133  TRP A CZ3 1 
ATOM   143  C CH2 . TRP A 1 133 ? 101.924 113.178 136.431 1.00 271.73 ?  133  TRP A CH2 1 
ATOM   144  N N   . SER A 1 134 ? 104.491 111.946 131.395 1.00 256.83 ?  134  SER A N   1 
ATOM   145  C CA  . SER A 1 134 ? 103.644 110.765 131.419 1.00 256.83 ?  134  SER A CA  1 
ATOM   146  C C   . SER A 1 134 ? 104.481 109.512 131.310 1.00 256.83 ?  134  SER A C   1 
ATOM   147  O O   . SER A 1 134 ? 104.320 108.589 132.099 1.00 256.83 ?  134  SER A O   1 
ATOM   148  C CB  . SER A 1 134 ? 102.636 110.818 130.280 1.00 256.83 ?  134  SER A CB  1 
ATOM   149  O OG  . SER A 1 134 ? 101.851 111.993 130.358 1.00 256.83 ?  134  SER A OG  1 
ATOM   150  N N   . MET A 1 135 ? 105.381 109.476 130.338 1.00 225.39 ?  135  MET A N   1 
ATOM   151  C CA  . MET A 1 135 ? 106.266 108.334 130.169 1.00 225.39 ?  135  MET A CA  1 
ATOM   152  C C   . MET A 1 135 ? 107.027 108.065 131.452 1.00 225.39 ?  135  MET A C   1 
ATOM   153  O O   . MET A 1 135 ? 106.986 106.959 131.978 1.00 225.39 ?  135  MET A O   1 
ATOM   154  C CB  . MET A 1 135 ? 107.236 108.620 129.027 1.00 225.39 ?  135  MET A CB  1 
ATOM   155  C CG  . MET A 1 135 ? 108.247 107.530 128.732 1.00 225.39 ?  135  MET A CG  1 
ATOM   156  S SD  . MET A 1 135 ? 108.470 107.383 126.953 1.00 225.39 ?  135  MET A SD  1 
ATOM   157  C CE  . MET A 1 135 ? 107.558 108.819 126.399 1.00 225.39 ?  135  MET A CE  1 
ATOM   158  N N   . GLY A 1 136 ? 107.707 109.076 131.974 1.00 217.14 ?  136  GLY A N   1 
ATOM   159  C CA  . GLY A 1 136 ? 108.467 108.917 133.198 1.00 217.14 ?  136  GLY A CA  1 
ATOM   160  C C   . GLY A 1 136 ? 107.628 108.518 134.386 1.00 217.14 ?  136  GLY A C   1 
ATOM   161  O O   . GLY A 1 136 ? 108.069 107.729 135.208 1.00 217.14 ?  136  GLY A O   1 
ATOM   162  N N   . TYR A 1 137 ? 106.421 109.055 134.485 1.00 223.63 ?  137  TYR A N   1 
ATOM   163  C CA  . TYR A 1 137 ? 105.530 108.717 135.582 1.00 223.63 ?  137  TYR A CA  1 
ATOM   164  C C   . TYR A 1 137 ? 105.207 107.238 135.561 1.00 223.63 ?  137  TYR A C   1 
ATOM   165  O O   . TYR A 1 137 ? 105.366 106.557 136.567 1.00 223.63 ?  137  TYR A O   1 
ATOM   166  C CB  . TYR A 1 137 ? 104.241 109.532 135.488 1.00 223.63 ?  137  TYR A CB  1 
ATOM   167  C CG  . TYR A 1 137 ? 103.240 109.251 136.580 1.00 223.63 ?  137  TYR A CG  1 
ATOM   168  C CD1 . TYR A 1 137 ? 103.387 109.808 137.838 1.00 223.63 ?  137  TYR A CD1 1 
ATOM   169  C CD2 . TYR A 1 137 ? 102.140 108.436 136.349 1.00 223.63 ?  137  TYR A CD2 1 
ATOM   170  C CE1 . TYR A 1 137 ? 102.473 109.558 138.841 1.00 223.63 ?  137  TYR A CE1 1 
ATOM   171  C CE2 . TYR A 1 137 ? 101.223 108.178 137.347 1.00 223.63 ?  137  TYR A CE2 1 
ATOM   172  C CZ  . TYR A 1 137 ? 101.395 108.743 138.591 1.00 223.63 ?  137  TYR A CZ  1 
ATOM   173  O OH  . TYR A 1 137 ? 100.485 108.492 139.590 1.00 223.63 ?  137  TYR A OH  1 
ATOM   174  N N   . VAL A 1 138 ? 104.756 106.733 134.419 1.00 233.63 ?  138  VAL A N   1 
ATOM   175  C CA  . VAL A 1 138 ? 104.381 105.329 134.326 1.00 233.63 ?  138  VAL A CA  1 
ATOM   176  C C   . VAL A 1 138 ? 105.598 104.438 134.515 1.00 233.63 ?  138  VAL A C   1 
ATOM   177  O O   . VAL A 1 138 ? 105.510 103.393 135.151 1.00 233.63 ?  138  VAL A O   1 
ATOM   178  C CB  . VAL A 1 138 ? 103.669 105.017 132.998 1.00 233.63 ?  138  VAL A CB  1 
ATOM   179  C CG1 . VAL A 1 138 ? 103.185 103.576 132.968 1.00 233.63 ?  138  VAL A CG1 1 
ATOM   180  C CG2 . VAL A 1 138 ? 102.494 105.960 132.799 1.00 233.63 ?  138  VAL A CG2 1 
ATOM   181  N N   . SER A 1 139 ? 106.745 104.861 133.997 1.00 209.26 ?  139  SER A N   1 
ATOM   182  C CA  . SER A 1 139 ? 107.968 104.085 134.155 1.00 209.26 ?  139  SER A CA  1 
ATOM   183  C C   . SER A 1 139 ? 108.393 104.021 135.612 1.00 209.26 ?  139  SER A C   1 
ATOM   184  O O   . SER A 1 139 ? 108.862 102.989 136.076 1.00 209.26 ?  139  SER A O   1 
ATOM   185  C CB  . SER A 1 139 ? 109.084 104.684 133.306 1.00 209.26 ?  139  SER A CB  1 
ATOM   186  O OG  . SER A 1 139 ? 110.111 105.223 134.117 1.00 209.26 ?  139  SER A OG  1 
ATOM   187  N N   . ALA A 1 140 ? 108.220 105.116 136.341 1.00 212.88 ?  140  ALA A N   1 
ATOM   188  C CA  . ALA A 1 140 ? 108.572 105.142 137.752 1.00 212.88 ?  140  ALA A CA  1 
ATOM   189  C C   . ALA A 1 140 ? 107.616 104.293 138.555 1.00 212.88 ?  140  ALA A C   1 
ATOM   190  O O   . ALA A 1 140 ? 108.016 103.652 139.518 1.00 212.88 ?  140  ALA A O   1 
ATOM   191  C CB  . ALA A 1 140 ? 108.564 106.564 138.272 1.00 212.88 ?  140  ALA A CB  1 
ATOM   192  N N   . LYS A 1 141 ? 106.350 104.281 138.161 1.00 223.66 ?  141  LYS A N   1 
ATOM   193  C CA  . LYS A 1 141 ? 105.362 103.475 138.860 1.00 223.66 ?  141  LYS A CA  1 
ATOM   194  C C   . LYS A 1 141 ? 105.635 102.011 138.599 1.00 223.66 ?  141  LYS A C   1 
ATOM   195  O O   . LYS A 1 141 ? 105.402 101.169 139.460 1.00 223.66 ?  141  LYS A O   1 
ATOM   196  C CB  . LYS A 1 141 ? 103.947 103.841 138.416 1.00 223.66 ?  141  LYS A CB  1 
ATOM   197  C CG  . LYS A 1 141 ? 103.452 105.201 138.886 1.00 223.66 ?  141  LYS A CG  1 
ATOM   198  C CD  . LYS A 1 141 ? 104.014 105.586 140.244 1.00 223.66 ?  141  LYS A CD  1 
ATOM   199  C CE  . LYS A 1 141 ? 104.717 106.934 140.187 1.00 223.66 ?  141  LYS A CE  1 
ATOM   200  N NZ  . LYS A 1 141 ? 105.028 107.466 141.541 1.00 223.66 1  141  LYS A NZ  1 
ATOM   201  N N   . SER A 1 142 ? 106.141 101.701 137.413 1.00 217.81 ?  142  SER A N   1 
ATOM   202  C CA  . SER A 1 142 ? 106.467 100.326 137.079 1.00 217.81 ?  142  SER A CA  1 
ATOM   203  C C   . SER A 1 142 ? 107.679 99.884  137.863 1.00 217.81 ?  142  SER A C   1 
ATOM   204  O O   . SER A 1 142 ? 107.742 98.753  138.327 1.00 217.81 ?  142  SER A O   1 
ATOM   205  C CB  . SER A 1 142 ? 106.735 100.193 135.587 1.00 217.81 ?  142  SER A CB  1 
ATOM   206  O OG  . SER A 1 142 ? 107.543 99.069  135.326 1.00 217.81 ?  142  SER A OG  1 
ATOM   207  N N   . LEU A 1 143 ? 108.645 100.778 138.026 1.00 215.31 ?  143  LEU A N   1 
ATOM   208  C CA  . LEU A 1 143 ? 109.833 100.458 138.802 1.00 215.31 ?  143  LEU A CA  1 
ATOM   209  C C   . LEU A 1 143 ? 109.470 100.257 140.261 1.00 215.31 ?  143  LEU A C   1 
ATOM   210  O O   . LEU A 1 143 ? 110.075 99.441  140.947 1.00 215.31 ?  143  LEU A O   1 
ATOM   211  C CB  . LEU A 1 143 ? 110.865 101.572 138.667 1.00 215.31 ?  143  LEU A CB  1 
ATOM   212  C CG  . LEU A 1 143 ? 112.211 101.192 138.060 1.00 215.31 ?  143  LEU A CG  1 
ATOM   213  C CD1 . LEU A 1 143 ? 112.148 99.806  137.443 1.00 215.31 ?  143  LEU A CD1 1 
ATOM   214  C CD2 . LEU A 1 143 ? 112.640 102.227 137.035 1.00 215.31 ?  143  LEU A CD2 1 
ATOM   215  N N   . GLN A 1 144 ? 108.476 100.993 140.741 1.00 242.10 ?  144  GLN A N   1 
ATOM   216  C CA  . GLN A 1 144 ? 108.037 100.842 142.118 1.00 242.10 ?  144  GLN A CA  1 
ATOM   217  C C   . GLN A 1 144 ? 107.336 99.515  142.312 1.00 242.10 ?  144  GLN A C   1 
ATOM   218  O O   . GLN A 1 144 ? 107.504 98.877  143.343 1.00 242.10 ?  144  GLN A O   1 
ATOM   219  C CB  . GLN A 1 144 ? 107.107 101.983 142.514 1.00 242.10 ?  144  GLN A CB  1 
ATOM   220  C CG  . GLN A 1 144 ? 107.829 103.251 142.930 1.00 242.10 ?  144  GLN A CG  1 
ATOM   221  C CD  . GLN A 1 144 ? 106.970 104.485 142.757 1.00 242.10 ?  144  GLN A CD  1 
ATOM   222  O OE1 . GLN A 1 144 ? 107.411 105.492 142.206 1.00 242.10 ?  144  GLN A OE1 1 
ATOM   223  N NE2 . GLN A 1 144 ? 105.732 104.412 143.229 1.00 242.10 ?  144  GLN A NE2 1 
ATOM   224  N N   . ALA A 1 145 ? 106.552 99.091  141.327 1.00 229.27 ?  145  ALA A N   1 
ATOM   225  C CA  . ALA A 1 145 ? 105.882 97.800  141.409 1.00 229.27 ?  145  ALA A CA  1 
ATOM   226  C C   . ALA A 1 145 ? 106.914 96.702  141.363 1.00 229.27 ?  145  ALA A C   1 
ATOM   227  O O   . ALA A 1 145 ? 106.774 95.697  142.043 1.00 229.27 ?  145  ALA A O   1 
ATOM   228  C CB  . ALA A 1 145 ? 104.898 97.641  140.273 1.00 229.27 ?  145  ALA A CB  1 
ATOM   229  N N   . TYR A 1 146 ? 107.955 96.886  140.561 1.00 220.90 ?  146  TYR A N   1 
ATOM   230  C CA  . TYR A 1 146 ? 109.037 95.915  140.480 1.00 220.90 ?  146  TYR A CA  1 
ATOM   231  C C   . TYR A 1 146 ? 109.613 95.727  141.861 1.00 220.90 ?  146  TYR A C   1 
ATOM   232  O O   . TYR A 1 146 ? 109.668 94.611  142.369 1.00 220.90 ?  146  TYR A O   1 
ATOM   233  C CB  . TYR A 1 146 ? 110.095 96.478  139.539 1.00 220.90 ?  146  TYR A CB  1 
ATOM   234  C CG  . TYR A 1 146 ? 111.250 95.581  139.177 1.00 220.90 ?  146  TYR A CG  1 
ATOM   235  C CD1 . TYR A 1 146 ? 111.176 94.203  139.316 1.00 220.90 ?  146  TYR A CD1 1 
ATOM   236  C CD2 . TYR A 1 146 ? 112.418 96.126  138.673 1.00 220.90 ?  146  TYR A CD2 1 
ATOM   237  C CE1 . TYR A 1 146 ? 112.243 93.399  138.972 1.00 220.90 ?  146  TYR A CE1 1 
ATOM   238  C CE2 . TYR A 1 146 ? 113.485 95.332  138.328 1.00 220.90 ?  146  TYR A CE2 1 
ATOM   239  C CZ  . TYR A 1 146 ? 113.393 93.972  138.479 1.00 220.90 ?  146  TYR A CZ  1 
ATOM   240  O OH  . TYR A 1 146 ? 114.467 93.197  138.127 1.00 220.90 ?  146  TYR A OH  1 
ATOM   241  N N   . LYS A 1 147 ? 110.031 96.821  142.482 1.00 198.72 ?  147  LYS A N   1 
ATOM   242  C CA  . LYS A 1 147 ? 110.616 96.747  143.812 1.00 198.72 ?  147  LYS A CA  1 
ATOM   243  C C   . LYS A 1 147 ? 109.656 96.158  144.832 1.00 198.72 ?  147  LYS A C   1 
ATOM   244  O O   . LYS A 1 147 ? 110.046 95.316  145.636 1.00 198.72 ?  147  LYS A O   1 
ATOM   245  C CB  . LYS A 1 147 ? 111.073 98.131  144.264 1.00 198.72 ?  147  LYS A CB  1 
ATOM   246  C CG  . LYS A 1 147 ? 112.493 98.475  143.855 1.00 198.72 ?  147  LYS A CG  1 
ATOM   247  C CD  . LYS A 1 147 ? 112.577 99.880  143.286 1.00 198.72 ?  147  LYS A CD  1 
ATOM   248  C CE  . LYS A 1 147 ? 113.597 99.952  142.164 1.00 198.72 ?  147  LYS A CE  1 
ATOM   249  N NZ  . LYS A 1 147 ? 114.832 99.194  142.508 1.00 198.72 1  147  LYS A NZ  1 
ATOM   250  N N   . TRP A 1 148 ? 108.402 96.591  144.801 1.00 237.89 ?  148  TRP A N   1 
ATOM   251  C CA  . TRP A 1 148 ? 107.414 96.096  145.751 1.00 237.89 ?  148  TRP A CA  1 
ATOM   252  C C   . TRP A 1 148 ? 107.173 94.601  145.600 1.00 237.89 ?  148  TRP A C   1 
ATOM   253  O O   . TRP A 1 148 ? 107.137 93.877  146.588 1.00 237.89 ?  148  TRP A O   1 
ATOM   254  C CB  . TRP A 1 148 ? 106.100 96.862  145.607 1.00 237.89 ?  148  TRP A CB  1 
ATOM   255  C CG  . TRP A 1 148 ? 104.950 96.224  146.311 1.00 237.89 ?  148  TRP A CG  1 
ATOM   256  C CD1 . TRP A 1 148 ? 104.714 96.214  147.653 1.00 237.89 ?  148  TRP A CD1 1 
ATOM   257  C CD2 . TRP A 1 148 ? 103.874 95.496  145.708 1.00 237.89 ?  148  TRP A CD2 1 
ATOM   258  N NE1 . TRP A 1 148 ? 103.558 95.525  147.925 1.00 237.89 ?  148  TRP A NE1 1 
ATOM   259  C CE2 . TRP A 1 148 ? 103.024 95.074  146.747 1.00 237.89 ?  148  TRP A CE2 1 
ATOM   260  C CE3 . TRP A 1 148 ? 103.549 95.160  144.392 1.00 237.89 ?  148  TRP A CE3 1 
ATOM   261  C CZ2 . TRP A 1 148 ? 101.869 94.335  146.510 1.00 237.89 ?  148  TRP A CZ2 1 
ATOM   262  C CZ3 . TRP A 1 148 ? 102.405 94.426  144.159 1.00 237.89 ?  148  TRP A CZ3 1 
ATOM   263  C CH2 . TRP A 1 148 ? 101.578 94.023  145.212 1.00 237.89 ?  148  TRP A CH2 1 
ATOM   264  N N   . SER A 1 149 ? 107.013 94.134  144.368 1.00 206.54 ?  149  SER A N   1 
ATOM   265  C CA  . SER A 1 149 ? 106.753 92.721  144.135 1.00 206.54 ?  149  SER A CA  1 
ATOM   266  C C   . SER A 1 149 ? 107.933 91.885  144.575 1.00 206.54 ?  149  SER A C   1 
ATOM   267  O O   . SER A 1 149 ? 107.765 90.811  145.152 1.00 206.54 ?  149  SER A O   1 
ATOM   268  C CB  . SER A 1 149 ? 106.454 92.465  142.664 1.00 206.54 ?  149  SER A CB  1 
ATOM   269  O OG  . SER A 1 149 ? 105.329 93.207  142.235 1.00 206.54 ?  149  SER A OG  1 
ATOM   270  N N   . TYR A 1 150 ? 109.137 92.375  144.312 1.00 168.90 ?  150  TYR A N   1 
ATOM   271  C CA  . TYR A 1 150 ? 110.333 91.658  144.713 1.00 168.90 ?  150  TYR A CA  1 
ATOM   272  C C   . TYR A 1 150 ? 110.354 91.527  146.222 1.00 168.90 ?  150  TYR A C   1 
ATOM   273  O O   . TYR A 1 150 ? 110.635 90.456  146.754 1.00 168.90 ?  150  TYR A O   1 
ATOM   274  C CB  . TYR A 1 150 ? 111.568 92.402  144.201 1.00 168.90 ?  150  TYR A CB  1 
ATOM   275  C CG  . TYR A 1 150 ? 112.882 91.935  144.773 1.00 168.90 ?  150  TYR A CG  1 
ATOM   276  C CD1 . TYR A 1 150 ? 113.479 90.764  144.330 1.00 168.90 ?  150  TYR A CD1 1 
ATOM   277  C CD2 . TYR A 1 150 ? 113.533 92.677  145.747 1.00 168.90 ?  150  TYR A CD2 1 
ATOM   278  C CE1 . TYR A 1 150 ? 114.687 90.342  144.848 1.00 168.90 ?  150  TYR A CE1 1 
ATOM   279  C CE2 . TYR A 1 150 ? 114.735 92.260  146.274 1.00 168.90 ?  150  TYR A CE2 1 
ATOM   280  C CZ  . TYR A 1 150 ? 115.306 91.095  145.821 1.00 168.90 ?  150  TYR A CZ  1 
ATOM   281  O OH  . TYR A 1 150 ? 116.501 90.691  146.355 1.00 168.90 ?  150  TYR A OH  1 
ATOM   282  N N   . ALA A 1 151 ? 110.030 92.609  146.918 1.00 187.55 ?  151  ALA A N   1 
ATOM   283  C CA  . ALA A 1 151 ? 110.070 92.595  148.373 1.00 187.55 ?  151  ALA A CA  1 
ATOM   284  C C   . ALA A 1 151 ? 108.918 91.825  148.994 1.00 187.55 ?  151  ALA A C   1 
ATOM   285  O O   . ALA A 1 151 ? 108.977 91.458  150.164 1.00 187.55 ?  151  ALA A O   1 
ATOM   286  C CB  . ALA A 1 151 ? 110.099 94.015  148.906 1.00 187.55 ?  151  ALA A CB  1 
ATOM   287  N N   . GLN A 1 152 ? 107.865 91.584  148.223 1.00 228.04 ?  152  GLN A N   1 
ATOM   288  C CA  . GLN A 1 152 ? 106.725 90.839  148.736 1.00 228.04 ?  152  GLN A CA  1 
ATOM   289  C C   . GLN A 1 152 ? 107.051 89.353  148.778 1.00 228.04 ?  152  GLN A C   1 
ATOM   290  O O   . GLN A 1 152 ? 106.470 88.609  149.567 1.00 228.04 ?  152  GLN A O   1 
ATOM   291  C CB  . GLN A 1 152 ? 105.460 91.139  147.922 1.00 228.04 ?  152  GLN A CB  1 
ATOM   292  C CG  . GLN A 1 152 ? 104.944 89.994  147.067 1.00 228.04 ?  152  GLN A CG  1 
ATOM   293  C CD  . GLN A 1 152 ? 104.364 90.467  145.751 1.00 228.04 ?  152  GLN A CD  1 
ATOM   294  O OE1 . GLN A 1 152 ? 103.751 91.529  145.679 1.00 228.04 ?  152  GLN A OE1 1 
ATOM   295  N NE2 . GLN A 1 152 ? 104.558 89.680  144.700 1.00 228.04 ?  152  GLN A NE2 1 
ATOM   296  N N   . MET A 1 153 ? 108.002 88.918  147.957 1.00 256.85 ?  153  MET A N   1 
ATOM   297  C CA  . MET A 1 153 ? 108.419 87.519  147.980 1.00 256.85 ?  153  MET A CA  1 
ATOM   298  C C   . MET A 1 153 ? 109.662 87.368  148.831 1.00 256.85 ?  153  MET A C   1 
ATOM   299  O O   . MET A 1 153 ? 110.359 86.365  148.714 1.00 256.85 ?  153  MET A O   1 
ATOM   300  C CB  . MET A 1 153 ? 108.718 87.030  146.565 1.00 256.85 ?  153  MET A CB  1 
ATOM   301  C CG  . MET A 1 153 ? 107.707 87.467  145.523 1.00 256.85 ?  153  MET A CG  1 
ATOM   302  S SD  . MET A 1 153 ? 106.134 86.607  145.688 1.00 256.85 ?  153  MET A SD  1 
ATOM   303  C CE  . MET A 1 153 ? 105.865 86.069  144.002 1.00 256.85 ?  153  MET A CE  1 
ATOM   304  N N   . GLN A 1 154 ? 109.933 88.337  149.698 1.00 267.26 ?  154  GLN A N   1 
ATOM   305  C CA  . GLN A 1 154 ? 111.159 88.328  150.510 1.00 267.26 ?  154  GLN A CA  1 
ATOM   306  C C   . GLN A 1 154 ? 111.744 86.991  150.986 1.00 267.26 ?  154  GLN A C   1 
ATOM   307  O O   . GLN A 1 154 ? 112.872 86.659  150.624 1.00 267.26 ?  154  GLN A O   1 
ATOM   308  C CB  . GLN A 1 154 ? 111.050 89.319  151.677 1.00 267.26 ?  154  GLN A CB  1 
ATOM   309  C CG  . GLN A 1 154 ? 112.388 89.850  152.164 1.00 267.26 ?  154  GLN A CG  1 
ATOM   310  C CD  . GLN A 1 154 ? 113.078 90.723  151.135 1.00 267.26 ?  154  GLN A CD  1 
ATOM   311  O OE1 . GLN A 1 154 ? 114.113 90.353  150.582 1.00 267.26 ?  154  GLN A OE1 1 
ATOM   312  N NE2 . GLN A 1 154 ? 112.508 91.893  150.875 1.00 267.26 ?  154  GLN A NE2 1 
ATOM   313  N N   . PRO A 1 155 ? 111.001 86.220  151.801 1.00 242.74 ?  155  PRO A N   1 
ATOM   314  C CA  . PRO A 1 155 ? 111.649 84.994  152.287 1.00 242.74 ?  155  PRO A CA  1 
ATOM   315  C C   . PRO A 1 155 ? 112.030 84.022  151.176 1.00 242.74 ?  155  PRO A C   1 
ATOM   316  O O   . PRO A 1 155 ? 113.169 83.562  151.148 1.00 242.74 ?  155  PRO A O   1 
ATOM   317  C CB  . PRO A 1 155 ? 110.582 84.364  153.192 1.00 242.74 ?  155  PRO A CB  1 
ATOM   318  C CG  . PRO A 1 155 ? 109.621 85.463  153.499 1.00 242.74 ?  155  PRO A CG  1 
ATOM   319  C CD  . PRO A 1 155 ? 109.608 86.316  152.272 1.00 242.74 ?  155  PRO A CD  1 
ATOM   320  N N   . SER A 1 156 ? 111.102 83.712  150.278 1.00 232.47 ?  156  SER A N   1 
ATOM   321  C CA  . SER A 1 156 ? 111.373 82.736  149.228 1.00 232.47 ?  156  SER A CA  1 
ATOM   322  C C   . SER A 1 156 ? 112.362 83.232  148.192 1.00 232.47 ?  156  SER A C   1 
ATOM   323  O O   . SER A 1 156 ? 112.026 84.073  147.366 1.00 232.47 ?  156  SER A O   1 
ATOM   324  C CB  . SER A 1 156 ? 110.076 82.332  148.536 1.00 232.47 ?  156  SER A CB  1 
ATOM   325  O OG  . SER A 1 156 ? 110.315 81.334  147.560 1.00 232.47 ?  156  SER A OG  1 
ATOM   326  N N   . LEU A 1 157 ? 113.578 82.700  148.221 1.00 209.06 ?  157  LEU A N   1 
ATOM   327  C CA  . LEU A 1 157 ? 114.587 83.082  147.233 1.00 209.06 ?  157  LEU A CA  1 
ATOM   328  C C   . LEU A 1 157 ? 114.243 82.712  145.783 1.00 209.06 ?  157  LEU A C   1 
ATOM   329  O O   . LEU A 1 157 ? 114.457 83.522  144.884 1.00 209.06 ?  157  LEU A O   1 
ATOM   330  C CB  . LEU A 1 157 ? 115.965 82.535  147.621 1.00 209.06 ?  157  LEU A CB  1 
ATOM   331  C CG  . LEU A 1 157 ? 117.060 83.574  147.856 1.00 209.06 ?  157  LEU A CG  1 
ATOM   332  C CD1 . LEU A 1 157 ? 118.050 83.569  146.703 1.00 209.06 ?  157  LEU A CD1 1 
ATOM   333  C CD2 . LEU A 1 157 ? 116.451 84.954  148.043 1.00 209.06 ?  157  LEU A CD2 1 
ATOM   334  N N   . PRO A 1 158 ? 113.719 81.492  145.536 1.00 201.91 ?  158  PRO A N   1 
ATOM   335  C CA  . PRO A 1 158 ? 113.348 81.227  144.141 1.00 201.91 ?  158  PRO A CA  1 
ATOM   336  C C   . PRO A 1 158 ? 112.264 82.163  143.614 1.00 201.91 ?  158  PRO A C   1 
ATOM   337  O O   . PRO A 1 158 ? 112.286 82.508  142.436 1.00 201.91 ?  158  PRO A O   1 
ATOM   338  C CB  . PRO A 1 158 ? 112.831 79.784  144.176 1.00 201.91 ?  158  PRO A CB  1 
ATOM   339  C CG  . PRO A 1 158 ? 112.624 79.457  145.616 1.00 201.91 ?  158  PRO A CG  1 
ATOM   340  C CD  . PRO A 1 158 ? 113.648 80.264  146.345 1.00 201.91 ?  158  PRO A CD  1 
ATOM   341  N N   . LEU A 1 159 ? 111.333 82.573  144.469 1.00 219.69 ?  159  LEU A N   1 
ATOM   342  C CA  . LEU A 1 159 ? 110.274 83.475  144.047 1.00 219.69 ?  159  LEU A CA  1 
ATOM   343  C C   . LEU A 1 159 ? 110.812 84.876  143.852 1.00 219.69 ?  159  LEU A C   1 
ATOM   344  O O   . LEU A 1 159 ? 110.343 85.604  142.982 1.00 219.69 ?  159  LEU A O   1 
ATOM   345  C CB  . LEU A 1 159 ? 109.134 83.480  145.056 1.00 219.69 ?  159  LEU A CB  1 
ATOM   346  C CG  . LEU A 1 159 ? 108.110 82.361  144.887 1.00 219.69 ?  159  LEU A CG  1 
ATOM   347  C CD1 . LEU A 1 159 ? 106.946 82.560  145.844 1.00 219.69 ?  159  LEU A CD1 1 
ATOM   348  C CD2 . LEU A 1 159 ? 107.626 82.303  143.447 1.00 219.69 ?  159  LEU A CD2 1 
ATOM   349  N N   . GLN A 1 160 ? 111.796 85.265  144.654 1.00 190.31 ?  160  GLN A N   1 
ATOM   350  C CA  . GLN A 1 160 ? 112.418 86.567  144.468 1.00 190.31 ?  160  GLN A CA  1 
ATOM   351  C C   . GLN A 1 160 ? 113.076 86.579  143.107 1.00 190.31 ?  160  GLN A C   1 
ATOM   352  O O   . GLN A 1 160 ? 113.010 87.575  142.397 1.00 190.31 ?  160  GLN A O   1 
ATOM   353  C CB  . GLN A 1 160 ? 113.450 86.837  145.555 1.00 190.31 ?  160  GLN A CB  1 
ATOM   354  C CG  . GLN A 1 160 ? 112.847 87.301  146.866 1.00 190.31 ?  160  GLN A CG  1 
ATOM   355  C CD  . GLN A 1 160 ? 113.715 88.303  147.594 1.00 190.31 ?  160  GLN A CD  1 
ATOM   356  O OE1 . GLN A 1 160 ? 114.882 88.041  147.877 1.00 190.31 ?  160  GLN A OE1 1 
ATOM   357  N NE2 . GLN A 1 160 ? 113.147 89.460  147.904 1.00 190.31 ?  160  GLN A NE2 1 
ATOM   358  N N   . PHE A 1 161 ? 113.696 85.465  142.731 1.00 210.02 ?  161  PHE A N   1 
ATOM   359  C CA  . PHE A 1 161 ? 114.314 85.365  141.415 1.00 210.02 ?  161  PHE A CA  1 
ATOM   360  C C   . PHE A 1 161 ? 113.270 85.526  140.338 1.00 210.02 ?  161  PHE A C   1 
ATOM   361  O O   . PHE A 1 161 ? 113.466 86.286  139.399 1.00 210.02 ?  161  PHE A O   1 
ATOM   362  C CB  . PHE A 1 161 ? 115.027 84.024  141.248 1.00 210.02 ?  161  PHE A CB  1 
ATOM   363  C CG  . PHE A 1 161 ? 115.872 83.939  140.012 1.00 210.02 ?  161  PHE A CG  1 
ATOM   364  C CD1 . PHE A 1 161 ? 117.043 84.665  139.909 1.00 210.02 ?  161  PHE A CD1 1 
ATOM   365  C CD2 . PHE A 1 161 ? 115.497 83.130  138.954 1.00 210.02 ?  161  PHE A CD2 1 
ATOM   366  C CE1 . PHE A 1 161 ? 117.827 84.589  138.776 1.00 210.02 ?  161  PHE A CE1 1 
ATOM   367  C CE2 . PHE A 1 161 ? 116.274 83.050  137.815 1.00 210.02 ?  161  PHE A CE2 1 
ATOM   368  C CZ  . PHE A 1 161 ? 117.442 83.780  137.727 1.00 210.02 ?  161  PHE A CZ  1 
ATOM   369  N N   . LEU A 1 162 ? 112.159 84.813  140.472 1.00 201.58 ?  162  LEU A N   1 
ATOM   370  C CA  . LEU A 1 162 ? 111.093 84.904  139.486 1.00 201.58 ?  162  LEU A CA  1 
ATOM   371  C C   . LEU A 1 162 ? 110.707 86.352  139.235 1.00 201.58 ?  162  LEU A C   1 
ATOM   372  O O   . LEU A 1 162 ? 110.777 86.821  138.111 1.00 201.58 ?  162  LEU A O   1 
ATOM   373  C CB  . LEU A 1 162 ? 109.876 84.095  139.924 1.00 201.58 ?  162  LEU A CB  1 
ATOM   374  C CG  . LEU A 1 162 ? 109.630 82.800  139.152 1.00 201.58 ?  162  LEU A CG  1 
ATOM   375  C CD1 . LEU A 1 162 ? 110.418 82.793  137.853 1.00 201.58 ?  162  LEU A CD1 1 
ATOM   376  C CD2 . LEU A 1 162 ? 109.987 81.592  140.003 1.00 201.58 ?  162  LEU A CD2 1 
ATOM   377  N N   . VAL A 1 163 ? 110.321 87.068  140.282 1.00 217.21 ?  163  VAL A N   1 
ATOM   378  C CA  . VAL A 1 163 ? 109.945 88.466  140.128 1.00 217.21 ?  163  VAL A CA  1 
ATOM   379  C C   . VAL A 1 163 ? 111.070 89.299  139.525 1.00 217.21 ?  163  VAL A C   1 
ATOM   380  O O   . VAL A 1 163 ? 110.846 90.064  138.590 1.00 217.21 ?  163  VAL A O   1 
ATOM   381  C CB  . VAL A 1 163 ? 109.511 89.085  141.462 1.00 217.21 ?  163  VAL A CB  1 
ATOM   382  C CG1 . VAL A 1 163 ? 109.246 90.570  141.290 1.00 217.21 ?  163  VAL A CG1 1 
ATOM   383  C CG2 . VAL A 1 163 ? 108.269 88.384  141.979 1.00 217.21 ?  163  VAL A CG2 1 
ATOM   384  N N   . TRP A 1 164 ? 112.285 89.135  140.035 1.00 191.84 ?  164  TRP A N   1 
ATOM   385  C CA  . TRP A 1 164 ? 113.410 89.919  139.542 1.00 191.84 ?  164  TRP A CA  1 
ATOM   386  C C   . TRP A 1 164 ? 113.704 89.719  138.061 1.00 191.84 ?  164  TRP A C   1 
ATOM   387  O O   . TRP A 1 164 ? 114.213 90.619  137.409 1.00 191.84 ?  164  TRP A O   1 
ATOM   388  C CB  . TRP A 1 164 ? 114.674 89.661  140.363 1.00 191.84 ?  164  TRP A CB  1 
ATOM   389  C CG  . TRP A 1 164 ? 115.716 90.712  140.155 1.00 191.84 ?  164  TRP A CG  1 
ATOM   390  C CD1 . TRP A 1 164 ? 116.804 90.634  139.341 1.00 191.84 ?  164  TRP A CD1 1 
ATOM   391  C CD2 . TRP A 1 164 ? 115.754 92.013  140.751 1.00 191.84 ?  164  TRP A CD2 1 
ATOM   392  N NE1 . TRP A 1 164 ? 117.522 91.801  139.396 1.00 191.84 ?  164  TRP A NE1 1 
ATOM   393  C CE2 . TRP A 1 164 ? 116.898 92.665  140.255 1.00 191.84 ?  164  TRP A CE2 1 
ATOM   394  C CE3 . TRP A 1 164 ? 114.932 92.690  141.656 1.00 191.84 ?  164  TRP A CE3 1 
ATOM   395  C CZ2 . TRP A 1 164 ? 117.244 93.956  140.636 1.00 191.84 ?  164  TRP A CZ2 1 
ATOM   396  C CZ3 . TRP A 1 164 ? 115.276 93.971  142.032 1.00 191.84 ?  164  TRP A CZ3 1 
ATOM   397  C CH2 . TRP A 1 164 ? 116.422 94.592  141.524 1.00 191.84 ?  164  TRP A CH2 1 
ATOM   398  N N   . VAL A 1 165 ? 113.409 88.546  137.521 1.00 211.85 ?  165  VAL A N   1 
ATOM   399  C CA  . VAL A 1 165 ? 113.744 88.303  136.127 1.00 211.85 ?  165  VAL A CA  1 
ATOM   400  C C   . VAL A 1 165 ? 112.555 88.411  135.186 1.00 211.85 ?  165  VAL A C   1 
ATOM   401  O O   . VAL A 1 165 ? 112.727 88.786  134.034 1.00 211.85 ?  165  VAL A O   1 
ATOM   402  C CB  . VAL A 1 165 ? 114.491 86.967  135.914 1.00 211.85 ?  165  VAL A CB  1 
ATOM   403  C CG1 . VAL A 1 165 ? 115.738 86.916  136.778 1.00 211.85 ?  165  VAL A CG1 1 
ATOM   404  C CG2 . VAL A 1 165 ? 113.588 85.771  136.172 1.00 211.85 ?  165  VAL A CG2 1 
ATOM   405  N N   . THR A 1 166 ? 111.352 88.113  135.666 1.00 246.51 ?  166  THR A N   1 
ATOM   406  C CA  . THR A 1 166 ? 110.188 88.122  134.787 1.00 246.51 ?  166  THR A CA  1 
ATOM   407  C C   . THR A 1 166 ? 109.619 89.507  134.591 1.00 246.51 ?  166  THR A C   1 
ATOM   408  O O   . THR A 1 166 ? 109.152 89.825  133.512 1.00 246.51 ?  166  THR A O   1 
ATOM   409  C CB  . THR A 1 166 ? 109.067 87.186  135.270 1.00 246.51 ?  166  THR A CB  1 
ATOM   410  O OG1 . THR A 1 166 ? 108.676 87.543  136.600 1.00 246.51 ?  166  THR A OG1 1 
ATOM   411  C CG2 . THR A 1 166 ? 109.527 85.738  135.236 1.00 246.51 ?  166  THR A CG2 1 
ATOM   412  N N   . PHE A 1 167 ? 109.641 90.335  135.624 1.00 237.22 ?  167  PHE A N   1 
ATOM   413  C CA  . PHE A 1 167 ? 109.186 91.710  135.457 1.00 237.22 ?  167  PHE A CA  1 
ATOM   414  C C   . PHE A 1 167 ? 109.918 92.393  134.295 1.00 237.22 ?  167  PHE A C   1 
ATOM   415  O O   . PHE A 1 167 ? 109.270 92.878  133.368 1.00 237.22 ?  167  PHE A O   1 
ATOM   416  C CB  . PHE A 1 167 ? 109.297 92.492  136.768 1.00 237.22 ?  167  PHE A CB  1 
ATOM   417  C CG  . PHE A 1 167 ? 108.389 93.682  136.850 1.00 237.22 ?  167  PHE A CG  1 
ATOM   418  C CD1 . PHE A 1 167 ? 108.747 94.886  136.270 1.00 237.22 ?  167  PHE A CD1 1 
ATOM   419  C CD2 . PHE A 1 167 ? 107.186 93.600  137.527 1.00 237.22 ?  167  PHE A CD2 1 
ATOM   420  C CE1 . PHE A 1 167 ? 107.916 95.982  136.351 1.00 237.22 ?  167  PHE A CE1 1 
ATOM   421  C CE2 . PHE A 1 167 ? 106.349 94.694  137.613 1.00 237.22 ?  167  PHE A CE2 1 
ATOM   422  C CZ  . PHE A 1 167 ? 106.714 95.887  137.023 1.00 237.22 ?  167  PHE A CZ  1 
ATOM   423  N N   . PRO A 1 168 ? 111.267 92.415  134.312 1.00 249.60 ?  168  PRO A N   1 
ATOM   424  C CA  . PRO A 1 168 ? 111.924 93.003  133.144 1.00 249.60 ?  168  PRO A CA  1 
ATOM   425  C C   . PRO A 1 168 ? 111.652 92.232  131.861 1.00 249.60 ?  168  PRO A C   1 
ATOM   426  O O   . PRO A 1 168 ? 111.468 92.855  130.826 1.00 249.60 ?  168  PRO A O   1 
ATOM   427  C CB  . PRO A 1 168 ? 113.403 92.895  133.490 1.00 249.60 ?  168  PRO A CB  1 
ATOM   428  C CG  . PRO A 1 168 ? 113.446 92.875  134.965 1.00 249.60 ?  168  PRO A CG  1 
ATOM   429  C CD  . PRO A 1 168 ? 112.251 92.068  135.351 1.00 249.60 ?  168  PRO A CD  1 
ATOM   430  N N   . LEU A 1 169 ? 111.632 90.905  131.922 1.00 300.80 ?  169  LEU A N   1 
ATOM   431  C CA  . LEU A 1 169 ? 111.388 90.094  130.736 1.00 300.80 ?  169  LEU A CA  1 
ATOM   432  C C   . LEU A 1 169 ? 110.085 90.481  130.083 1.00 300.80 ?  169  LEU A C   1 
ATOM   433  O O   . LEU A 1 169 ? 110.060 90.792  128.902 1.00 300.80 ?  169  LEU A O   1 
ATOM   434  C CB  . LEU A 1 169 ? 111.364 88.607  131.076 1.00 300.80 ?  169  LEU A CB  1 
ATOM   435  C CG  . LEU A 1 169 ? 112.605 87.806  130.691 1.00 300.80 ?  169  LEU A CG  1 
ATOM   436  C CD1 . LEU A 1 169 ? 112.604 86.454  131.386 1.00 300.80 ?  169  LEU A CD1 1 
ATOM   437  C CD2 . LEU A 1 169 ? 112.658 87.635  129.185 1.00 300.80 ?  169  LEU A CD2 1 
ATOM   438  N N   . VAL A 1 170 ? 109.002 90.469  130.849 1.00 303.99 ?  170  VAL A N   1 
ATOM   439  C CA  . VAL A 1 170 ? 107.695 90.814  130.308 1.00 303.99 ?  170  VAL A CA  1 
ATOM   440  C C   . VAL A 1 170 ? 107.736 92.191  129.679 1.00 303.99 ?  170  VAL A C   1 
ATOM   441  O O   . VAL A 1 170 ? 107.323 92.363  128.540 1.00 303.99 ?  170  VAL A O   1 
ATOM   442  C CB  . VAL A 1 170 ? 106.604 90.760  131.392 1.00 303.99 ?  170  VAL A CB  1 
ATOM   443  C CG1 . VAL A 1 170 ? 105.322 91.423  130.911 1.00 303.99 ?  170  VAL A CG1 1 
ATOM   444  C CG2 . VAL A 1 170 ? 106.334 89.319  131.791 1.00 303.99 ?  170  VAL A CG2 1 
ATOM   445  N N   . LEU A 1 171 ? 108.269 93.167  130.398 1.00 296.97 ?  171  LEU A N   1 
ATOM   446  C CA  . LEU A 1 171 ? 108.291 94.530  129.888 1.00 296.97 ?  171  LEU A CA  1 
ATOM   447  C C   . LEU A 1 171 ? 109.108 94.695  128.611 1.00 296.97 ?  171  LEU A C   1 
ATOM   448  O O   . LEU A 1 171 ? 108.691 95.397  127.700 1.00 296.97 ?  171  LEU A O   1 
ATOM   449  C CB  . LEU A 1 171 ? 108.767 95.491  130.972 1.00 296.97 ?  171  LEU A CB  1 
ATOM   450  C CG  . LEU A 1 171 ? 107.689 95.839  131.995 1.00 296.97 ?  171  LEU A CG  1 
ATOM   451  C CD1 . LEU A 1 171 ? 108.023 97.149  132.679 1.00 296.97 ?  171  LEU A CD1 1 
ATOM   452  C CD2 . LEU A 1 171 ? 106.328 95.926  131.325 1.00 296.97 ?  171  LEU A CD2 1 
ATOM   453  N N   . ILE A 1 172 ? 110.260 94.042  128.532 1.00 290.81 ?  172  ILE A N   1 
ATOM   454  C CA  . ILE A 1 172 ? 111.106 94.148  127.346 1.00 290.81 ?  172  ILE A CA  1 
ATOM   455  C C   . ILE A 1 172 ? 110.505 93.368  126.191 1.00 290.81 ?  172  ILE A C   1 
ATOM   456  O O   . ILE A 1 172 ? 110.510 93.829  125.054 1.00 290.81 ?  172  ILE A O   1 
ATOM   457  C CB  . ILE A 1 172 ? 112.548 93.679  127.622 1.00 290.81 ?  172  ILE A CB  1 
ATOM   458  C CG1 . ILE A 1 172 ? 113.237 94.634  128.595 1.00 290.81 ?  172  ILE A CG1 1 
ATOM   459  C CG2 . ILE A 1 172 ? 113.349 93.595  126.334 1.00 290.81 ?  172  ILE A CG2 1 
ATOM   460  C CD1 . ILE A 1 172 ? 113.388 96.041  128.064 1.00 290.81 ?  172  ILE A CD1 1 
ATOM   461  N N   . LEU A 1 173 ? 109.955 92.196  126.477 1.00 334.45 ?  173  LEU A N   1 
ATOM   462  C CA  . LEU A 1 173 ? 109.300 91.421  125.433 1.00 334.45 ?  173  LEU A CA  1 
ATOM   463  C C   . LEU A 1 173 ? 108.122 92.211  124.902 1.00 334.45 ?  173  LEU A C   1 
ATOM   464  O O   . LEU A 1 173 ? 107.879 92.225  123.703 1.00 334.45 ?  173  LEU A O   1 
ATOM   465  C CB  . LEU A 1 173 ? 108.835 90.070  125.965 1.00 334.45 ?  173  LEU A CB  1 
ATOM   466  C CG  . LEU A 1 173 ? 109.642 88.848  125.528 1.00 334.45 ?  173  LEU A CG  1 
ATOM   467  C CD1 . LEU A 1 173 ? 111.062 89.239  125.158 1.00 334.45 ?  173  LEU A CD1 1 
ATOM   468  C CD2 . LEU A 1 173 ? 109.640 87.793  126.621 1.00 334.45 ?  173  LEU A CD2 1 
ATOM   469  N N   . PHE A 1 174 ? 107.396 92.883  125.788 1.00 322.85 ?  174  PHE A N   1 
ATOM   470  C CA  . PHE A 1 174 ? 106.283 93.716  125.359 1.00 322.85 ?  174  PHE A CA  1 
ATOM   471  C C   . PHE A 1 174 ? 106.778 94.855  124.489 1.00 322.85 ?  174  PHE A C   1 
ATOM   472  O O   . PHE A 1 174 ? 106.214 95.107  123.437 1.00 322.85 ?  174  PHE A O   1 
ATOM   473  C CB  . PHE A 1 174 ? 105.520 94.269  126.558 1.00 322.85 ?  174  PHE A CB  1 
ATOM   474  C CG  . PHE A 1 174 ? 104.506 95.313  126.200 1.00 322.85 ?  174  PHE A CG  1 
ATOM   475  C CD1 . PHE A 1 174 ? 103.368 94.976  125.488 1.00 322.85 ?  174  PHE A CD1 1 
ATOM   476  C CD2 . PHE A 1 174 ? 104.693 96.633  126.570 1.00 322.85 ?  174  PHE A CD2 1 
ATOM   477  C CE1 . PHE A 1 174 ? 102.434 95.935  125.152 1.00 322.85 ?  174  PHE A CE1 1 
ATOM   478  C CE2 . PHE A 1 174 ? 103.764 97.596  126.237 1.00 322.85 ?  174  PHE A CE2 1 
ATOM   479  C CZ  . PHE A 1 174 ? 102.632 97.247  125.529 1.00 322.85 ?  174  PHE A CZ  1 
ATOM   480  N N   . SER A 1 175 ? 107.826 95.548  124.919 1.00 290.57 ?  175  SER A N   1 
ATOM   481  C CA  . SER A 1 175 ? 108.391 96.623  124.116 1.00 290.57 ?  175  SER A CA  1 
ATOM   482  C C   . SER A 1 175 ? 108.668 96.128  122.718 1.00 290.57 ?  175  SER A C   1 
ATOM   483  O O   . SER A 1 175 ? 108.225 96.730  121.744 1.00 290.57 ?  175  SER A O   1 
ATOM   484  C CB  . SER A 1 175 ? 109.692 97.132  124.727 1.00 290.57 ?  175  SER A CB  1 
ATOM   485  O OG  . SER A 1 175 ? 109.520 97.515  126.075 1.00 290.57 ?  175  SER A OG  1 
ATOM   486  N N   . ALA A 1 176 ? 109.397 95.025  122.612 1.00 295.67 ?  176  ALA A N   1 
ATOM   487  C CA  . ALA A 1 176 ? 109.738 94.475  121.310 1.00 295.67 ?  176  ALA A CA  1 
ATOM   488  C C   . ALA A 1 176 ? 108.499 94.129  120.508 1.00 295.67 ?  176  ALA A C   1 
ATOM   489  O O   . ALA A 1 176 ? 108.380 94.526  119.355 1.00 295.67 ?  176  ALA A O   1 
ATOM   490  C CB  . ALA A 1 176 ? 110.621 93.253  121.478 1.00 295.67 ?  176  ALA A CB  1 
ATOM   491  N N   . LEU A 1 177 ? 107.574 93.394  121.112 1.00 323.50 ?  177  LEU A N   1 
ATOM   492  C CA  . LEU A 1 177 ? 106.364 92.989  120.414 1.00 323.50 ?  177  LEU A CA  1 
ATOM   493  C C   . LEU A 1 177 ? 105.560 94.187  119.955 1.00 323.50 ?  177  LEU A C   1 
ATOM   494  O O   . LEU A 1 177 ? 105.138 94.247  118.806 1.00 323.50 ?  177  LEU A O   1 
ATOM   495  C CB  . LEU A 1 177 ? 105.503 92.105  121.308 1.00 323.50 ?  177  LEU A CB  1 
ATOM   496  C CG  . LEU A 1 177 ? 104.703 91.018  120.595 1.00 323.50 ?  177  LEU A CG  1 
ATOM   497  C CD1 . LEU A 1 177 ? 105.505 90.426  119.446 1.00 323.50 ?  177  LEU A CD1 1 
ATOM   498  C CD2 . LEU A 1 177 ? 104.278 89.937  121.575 1.00 323.50 ?  177  LEU A CD2 1 
ATOM   499  N N   . PHE A 1 178 ? 105.343 95.141  120.849 1.00 305.78 ?  178  PHE A N   1 
ATOM   500  C CA  . PHE A 1 178 ? 104.586 96.333  120.500 1.00 305.78 ?  178  PHE A CA  1 
ATOM   501  C C   . PHE A 1 178 ? 105.213 97.009  119.300 1.00 305.78 ?  178  PHE A C   1 
ATOM   502  O O   . PHE A 1 178 ? 104.541 97.262  118.313 1.00 305.78 ?  178  PHE A O   1 
ATOM   503  C CB  . PHE A 1 178 ? 104.527 97.304  121.675 1.00 305.78 ?  178  PHE A CB  1 
ATOM   504  C CG  . PHE A 1 178 ? 103.401 98.288  121.589 1.00 305.78 ?  178  PHE A CG  1 
ATOM   505  C CD1 . PHE A 1 178 ? 102.097 97.884  121.808 1.00 305.78 ?  178  PHE A CD1 1 
ATOM   506  C CD2 . PHE A 1 178 ? 103.645 99.614  121.289 1.00 305.78 ?  178  PHE A CD2 1 
ATOM   507  C CE1 . PHE A 1 178 ? 101.056 98.786  121.731 1.00 305.78 ?  178  PHE A CE1 1 
ATOM   508  C CE2 . PHE A 1 178 ? 102.609 100.521 121.206 1.00 305.78 ?  178  PHE A CE2 1 
ATOM   509  C CZ  . PHE A 1 178 ? 101.312 100.108 121.430 1.00 305.78 ?  178  PHE A CZ  1 
ATOM   510  N N   . CYS A 1 179 ? 106.503 97.297  119.379 1.00 247.55 ?  179  CYS A N   1 
ATOM   511  C CA  . CYS A 1 179 ? 107.192 97.920  118.263 1.00 247.55 ?  179  CYS A CA  1 
ATOM   512  C C   . CYS A 1 179 ? 107.004 97.118  116.989 1.00 247.55 ?  179  CYS A C   1 
ATOM   513  O O   . CYS A 1 179 ? 106.514 97.637  115.999 1.00 247.55 ?  179  CYS A O   1 
ATOM   514  C CB  . CYS A 1 179 ? 108.673 98.075  118.574 1.00 247.55 ?  179  CYS A CB  1 
ATOM   515  S SG  . CYS A 1 179 ? 109.091 99.692  119.246 1.00 247.55 ?  179  CYS A SG  1 
ATOM   516  N N   . HIS A 1 180 ? 107.370 95.846  117.013 1.00 321.14 ?  180  HIS A N   1 
ATOM   517  C CA  . HIS A 1 180 ? 107.209 94.996  115.842 1.00 321.14 ?  180  HIS A CA  1 
ATOM   518  C C   . HIS A 1 180 ? 105.832 95.134  115.225 1.00 321.14 ?  180  HIS A C   1 
ATOM   519  O O   . HIS A 1 180 ? 105.708 95.353  114.022 1.00 321.14 ?  180  HIS A O   1 
ATOM   520  C CB  . HIS A 1 180 ? 107.451 93.535  116.215 1.00 321.14 ?  180  HIS A CB  1 
ATOM   521  C CG  . HIS A 1 180 ? 107.485 92.611  115.040 1.00 321.14 ?  180  HIS A CG  1 
ATOM   522  N ND1 . HIS A 1 180 ? 108.158 92.913  113.876 1.00 321.14 ?  180  HIS A ND1 1 
ATOM   523  C CD2 . HIS A 1 180 ? 106.929 91.392  114.848 1.00 321.14 ?  180  HIS A CD2 1 
ATOM   524  C CE1 . HIS A 1 180 ? 108.015 91.920  113.017 1.00 321.14 ?  180  HIS A CE1 1 
ATOM   525  N NE2 . HIS A 1 180 ? 107.274 90.984  113.582 1.00 321.14 ?  180  HIS A NE2 1 
ATOM   526  N N   . LEU A 1 181 ? 104.793 95.010  116.041 1.00 330.88 ?  181  LEU A N   1 
ATOM   527  C CA  . LEU A 1 181 ? 103.431 95.071  115.527 1.00 330.88 ?  181  LEU A CA  1 
ATOM   528  C C   . LEU A 1 181 ? 103.056 96.454  115.025 1.00 330.88 ?  181  LEU A C   1 
ATOM   529  O O   . LEU A 1 181 ? 102.654 96.605  113.875 1.00 330.88 ?  181  LEU A O   1 
ATOM   530  C CB  . LEU A 1 181 ? 102.443 94.625  116.602 1.00 330.88 ?  181  LEU A CB  1 
ATOM   531  C CG  . LEU A 1 181 ? 101.993 93.163  116.580 1.00 330.88 ?  181  LEU A CG  1 
ATOM   532  C CD1 . LEU A 1 181 ? 102.765 92.352  115.549 1.00 330.88 ?  181  LEU A CD1 1 
ATOM   533  C CD2 . LEU A 1 181 ? 102.121 92.543  117.961 1.00 330.88 ?  181  LEU A CD2 1 
ATOM   534  N N   . ILE A 1 182 ? 103.178 97.463  115.876 1.00 337.23 ?  182  ILE A N   1 
ATOM   535  C CA  . ILE A 1 182 ? 102.782 98.813  115.492 1.00 337.23 ?  182  ILE A CA  1 
ATOM   536  C C   . ILE A 1 182 ? 103.698 99.415  114.434 1.00 337.23 ?  182  ILE A C   1 
ATOM   537  O O   . ILE A 1 182 ? 103.303 99.556  113.277 1.00 337.23 ?  182  ILE A O   1 
ATOM   538  C CB  . ILE A 1 182 ? 102.693 99.742  116.714 1.00 337.23 ?  182  ILE A CB  1 
ATOM   539  C CG1 . ILE A 1 182 ? 101.854 99.088  117.807 1.00 337.23 ?  182  ILE A CG1 1 
ATOM   540  C CG2 . ILE A 1 182 ? 102.071 101.074 116.330 1.00 337.23 ?  182  ILE A CG2 1 
ATOM   541  C CD1 . ILE A 1 182 ? 100.365 99.182  117.568 1.00 337.23 ?  182  ILE A CD1 1 
ATOM   542  N N   . SER A 1 183 ? 104.916 99.771  114.818 1.00 277.75 ?  183  SER A N   1 
ATOM   543  C CA  . SER A 1 183 ? 105.854 100.352 113.871 1.00 277.75 ?  183  SER A CA  1 
ATOM   544  C C   . SER A 1 183 ? 107.240 99.779  114.075 1.00 277.75 ?  183  SER A C   1 
ATOM   545  O O   . SER A 1 183 ? 107.910 100.102 115.053 1.00 277.75 ?  183  SER A O   1 
ATOM   546  C CB  . SER A 1 183 ? 105.890 101.865 114.021 1.00 277.75 ?  183  SER A CB  1 
ATOM   547  O OG  . SER A 1 183 ? 107.161 102.383 113.682 1.00 277.75 ?  183  SER A OG  1 
ATOM   548  N N   . PRO A 1 184 ? 107.684 98.916  113.153 1.00 290.93 ?  184  PRO A N   1 
ATOM   549  C CA  . PRO A 1 184 ? 108.997 98.277  113.287 1.00 290.93 ?  184  PRO A CA  1 
ATOM   550  C C   . PRO A 1 184 ? 110.163 99.224  113.041 1.00 290.93 ?  184  PRO A C   1 
ATOM   551  O O   . PRO A 1 184 ? 111.309 98.790  113.108 1.00 290.93 ?  184  PRO A O   1 
ATOM   552  C CB  . PRO A 1 184 ? 108.966 97.195  112.210 1.00 290.93 ?  184  PRO A CB  1 
ATOM   553  C CG  . PRO A 1 184 ? 107.994 97.695  111.198 1.00 290.93 ?  184  PRO A CG  1 
ATOM   554  C CD  . PRO A 1 184 ? 106.946 98.435  111.973 1.00 290.93 ?  184  PRO A CD  1 
ATOM   555  N N   . GLN A 1 185 ? 109.887 100.490 112.757 1.00 300.55 ?  185  GLN A N   1 
ATOM   556  C CA  . GLN A 1 185 ? 110.950 101.464 112.571 1.00 300.55 ?  185  GLN A CA  1 
ATOM   557  C C   . GLN A 1 185 ? 111.072 102.319 113.815 1.00 300.55 ?  185  GLN A C   1 
ATOM   558  O O   . GLN A 1 185 ? 111.840 103.268 113.848 1.00 300.55 ?  185  GLN A O   1 
ATOM   559  C CB  . GLN A 1 185 ? 110.695 102.335 111.338 1.00 300.55 ?  185  GLN A CB  1 
ATOM   560  C CG  . GLN A 1 185 ? 109.302 102.931 111.257 1.00 300.55 ?  185  GLN A CG  1 
ATOM   561  C CD  . GLN A 1 185 ? 108.364 102.110 110.395 1.00 300.55 ?  185  GLN A CD  1 
ATOM   562  O OE1 . GLN A 1 185 ? 108.793 101.213 109.670 1.00 300.55 ?  185  GLN A OE1 1 
ATOM   563  N NE2 . GLN A 1 185 ? 107.073 102.412 110.472 1.00 300.55 ?  185  GLN A NE2 1 
ATOM   564  N N   . ALA A 1 186 ? 110.324 101.974 114.854 1.00 285.83 ?  186  ALA A N   1 
ATOM   565  C CA  . ALA A 1 186 ? 110.415 102.712 116.104 1.00 285.83 ?  186  ALA A CA  1 
ATOM   566  C C   . ALA A 1 186 ? 111.375 102.029 117.057 1.00 285.83 ?  186  ALA A C   1 
ATOM   567  O O   . ALA A 1 186 ? 111.189 102.083 118.267 1.00 285.83 ?  186  ALA A O   1 
ATOM   568  C CB  . ALA A 1 186 ? 109.048 102.841 116.742 1.00 285.83 ?  186  ALA A CB  1 
ATOM   569  N N   . VAL A 1 187 ? 112.402 101.383 116.519 1.00 285.09 ?  187  VAL A N   1 
ATOM   570  C CA  . VAL A 1 187 ? 113.380 100.703 117.353 1.00 285.09 ?  187  VAL A CA  1 
ATOM   571  C C   . VAL A 1 187 ? 114.760 101.318 117.206 1.00 285.09 ?  187  VAL A C   1 
ATOM   572  O O   . VAL A 1 187 ? 115.046 101.973 116.205 1.00 285.09 ?  187  VAL A O   1 
ATOM   573  C CB  . VAL A 1 187 ? 113.468 99.202  117.009 1.00 285.09 ?  187  VAL A CB  1 
ATOM   574  C CG1 . VAL A 1 187 ? 112.175 98.493  117.369 1.00 285.09 ?  187  VAL A CG1 1 
ATOM   575  C CG2 . VAL A 1 187 ? 113.790 99.004  115.537 1.00 285.09 ?  187  VAL A CG2 1 
ATOM   576  N N   . GLY A 1 188 ? 115.612 101.136 118.205 1.00 258.62 ?  188  GLY A N   1 
ATOM   577  C CA  . GLY A 1 188 ? 116.982 101.612 118.105 1.00 258.62 ?  188  GLY A CA  1 
ATOM   578  C C   . GLY A 1 188 ? 117.248 103.095 117.999 1.00 258.62 ?  188  GLY A C   1 
ATOM   579  O O   . GLY A 1 188 ? 117.612 103.568 116.921 1.00 258.62 ?  188  GLY A O   1 
ATOM   580  N N   . SER A 1 189 ? 117.084 103.828 119.096 1.00 249.74 ?  189  SER A N   1 
ATOM   581  C CA  . SER A 1 189 ? 117.391 105.262 119.119 1.00 249.74 ?  189  SER A CA  1 
ATOM   582  C C   . SER A 1 189 ? 116.659 106.096 118.086 1.00 249.74 ?  189  SER A C   1 
ATOM   583  O O   . SER A 1 189 ? 115.653 105.676 117.526 1.00 249.74 ?  189  SER A O   1 
ATOM   584  C CB  . SER A 1 189 ? 118.903 105.494 119.009 1.00 249.74 ?  189  SER A CB  1 
ATOM   585  O OG  . SER A 1 189 ? 119.341 106.520 119.880 1.00 249.74 ?  189  SER A OG  1 
ATOM   586  N N   . GLY A 1 190 ? 117.156 107.297 117.845 1.00 248.75 ?  190  GLY A N   1 
ATOM   587  C CA  . GLY A 1 190 ? 116.534 108.164 116.870 1.00 248.75 ?  190  GLY A CA  1 
ATOM   588  C C   . GLY A 1 190 ? 117.587 109.082 116.320 1.00 248.75 ?  190  GLY A C   1 
ATOM   589  O O   . GLY A 1 190 ? 117.516 109.470 115.165 1.00 248.75 ?  190  GLY A O   1 
ATOM   590  N N   . ILE A 1 191 ? 118.573 109.421 117.142 1.00 237.15 ?  191  ILE A N   1 
ATOM   591  C CA  . ILE A 1 191 ? 119.668 110.276 116.696 1.00 237.15 ?  191  ILE A CA  1 
ATOM   592  C C   . ILE A 1 191 ? 120.371 109.808 115.417 1.00 237.15 ?  191  ILE A C   1 
ATOM   593  O O   . ILE A 1 191 ? 120.602 110.618 114.524 1.00 237.15 ?  191  ILE A O   1 
ATOM   594  C CB  . ILE A 1 191 ? 120.701 110.497 117.815 1.00 237.15 ?  191  ILE A CB  1 
ATOM   595  C CG1 . ILE A 1 191 ? 119.997 110.736 119.148 1.00 237.15 ?  191  ILE A CG1 1 
ATOM   596  C CG2 . ILE A 1 191 ? 121.614 111.660 117.478 1.00 237.15 ?  191  ILE A CG2 1 
ATOM   597  C CD1 . ILE A 1 191 ? 120.466 111.978 119.868 1.00 237.15 ?  191  ILE A CD1 1 
ATOM   598  N N   . PRO A 1 192 ? 120.715 108.508 115.306 1.00 265.78 ?  192  PRO A N   1 
ATOM   599  C CA  . PRO A 1 192 ? 121.341 108.126 114.036 1.00 265.78 ?  192  PRO A CA  1 
ATOM   600  C C   . PRO A 1 192 ? 120.469 108.447 112.832 1.00 265.78 ?  192  PRO A C   1 
ATOM   601  O O   . PRO A 1 192 ? 120.945 109.027 111.856 1.00 265.78 ?  192  PRO A O   1 
ATOM   602  C CB  . PRO A 1 192 ? 121.484 106.612 114.166 1.00 265.78 ?  192  PRO A CB  1 
ATOM   603  C CG  . PRO A 1 192 ? 121.586 106.368 115.623 1.00 265.78 ?  192  PRO A CG  1 
ATOM   604  C CD  . PRO A 1 192 ? 120.697 107.384 116.262 1.00 265.78 ?  192  PRO A CD  1 
ATOM   605  N N   . GLU A 1 193 ? 119.198 108.084 112.897 1.00 275.33 ?  193  GLU A N   1 
ATOM   606  C CA  . GLU A 1 193 ? 118.311 108.299 111.767 1.00 275.33 ?  193  GLU A CA  1 
ATOM   607  C C   . GLU A 1 193 ? 117.894 109.753 111.607 1.00 275.33 ?  193  GLU A C   1 
ATOM   608  O O   . GLU A 1 193 ? 117.558 110.176 110.509 1.00 275.33 ?  193  GLU A O   1 
ATOM   609  C CB  . GLU A 1 193 ? 117.095 107.391 111.890 1.00 275.33 ?  193  GLU A CB  1 
ATOM   610  C CG  . GLU A 1 193 ? 117.436 105.909 111.840 1.00 275.33 ?  193  GLU A CG  1 
ATOM   611  C CD  . GLU A 1 193 ? 117.369 105.236 113.199 1.00 275.33 ?  193  GLU A CD  1 
ATOM   612  O OE1 . GLU A 1 193 ? 117.962 105.761 114.165 1.00 275.33 ?  193  GLU A OE1 1 
ATOM   613  O OE2 . GLU A 1 193 ? 116.714 104.179 113.306 1.00 275.33 -1 193  GLU A OE2 1 
ATOM   614  N N   . MET A 1 194 ? 117.923 110.524 112.685 1.00 255.21 ?  194  MET A N   1 
ATOM   615  C CA  . MET A 1 194 ? 117.609 111.942 112.589 1.00 255.21 ?  194  MET A CA  1 
ATOM   616  C C   . MET A 1 194 ? 118.731 112.640 111.862 1.00 255.21 ?  194  MET A C   1 
ATOM   617  O O   . MET A 1 194 ? 118.486 113.568 111.108 1.00 255.21 ?  194  MET A O   1 
ATOM   618  C CB  . MET A 1 194 ? 117.426 112.562 113.969 1.00 255.21 ?  194  MET A CB  1 
ATOM   619  C CG  . MET A 1 194 ? 115.975 112.761 114.364 1.00 255.21 ?  194  MET A CG  1 
ATOM   620  S SD  . MET A 1 194 ? 115.004 113.502 113.041 1.00 255.21 ?  194  MET A SD  1 
ATOM   621  C CE  . MET A 1 194 ? 113.871 112.165 112.689 1.00 255.21 ?  194  MET A CE  1 
ATOM   622  N N   . LYS A 1 195 ? 119.964 112.201 112.085 1.00 246.75 ?  195  LYS A N   1 
ATOM   623  C CA  . LYS A 1 195 ? 121.096 112.769 111.372 1.00 246.75 ?  195  LYS A CA  1 
ATOM   624  C C   . LYS A 1 195 ? 120.864 112.564 109.894 1.00 246.75 ?  195  LYS A C   1 
ATOM   625  O O   . LYS A 1 195 ? 121.025 113.488 109.102 1.00 246.75 ?  195  LYS A O   1 
ATOM   626  C CB  . LYS A 1 195 ? 122.374 112.053 111.779 1.00 246.75 ?  195  LYS A CB  1 
ATOM   627  C CG  . LYS A 1 195 ? 123.286 112.839 112.698 1.00 246.75 ?  195  LYS A CG  1 
ATOM   628  C CD  . LYS A 1 195 ? 124.470 111.989 113.127 1.00 246.75 ?  195  LYS A CD  1 
ATOM   629  C CE  . LYS A 1 195 ? 125.724 112.832 113.277 1.00 246.75 ?  195  LYS A CE  1 
ATOM   630  N NZ  . LYS A 1 195 ? 125.469 114.258 112.933 1.00 246.75 1  195  LYS A NZ  1 
ATOM   631  N N   . THR A 1 196 ? 120.478 111.350 109.518 1.00 271.27 ?  196  THR A N   1 
ATOM   632  C CA  . THR A 1 196 ? 120.199 111.046 108.120 1.00 271.27 ?  196  THR A CA  1 
ATOM   633  C C   . THR A 1 196 ? 119.086 111.926 107.562 1.00 271.27 ?  196  THR A C   1 
ATOM   634  O O   . THR A 1 196 ? 119.238 112.521 106.497 1.00 271.27 ?  196  THR A O   1 
ATOM   635  C CB  . THR A 1 196 ? 119.811 109.565 107.974 1.00 271.27 ?  196  THR A CB  1 
ATOM   636  O OG1 . THR A 1 196 ? 120.811 108.751 108.597 1.00 271.27 ?  196  THR A OG1 1 
ATOM   637  C CG2 . THR A 1 196 ? 119.683 109.170 106.519 1.00 271.27 ?  196  THR A CG2 1 
ATOM   638  N N   . ILE A 1 197 ? 117.966 112.018 108.275 1.00 285.13 ?  197  ILE A N   1 
ATOM   639  C CA  . ILE A 1 197 ? 116.835 112.833 107.822 1.00 285.13 ?  197  ILE A CA  1 
ATOM   640  C C   . ILE A 1 197 ? 117.219 114.302 107.697 1.00 285.13 ?  197  ILE A C   1 
ATOM   641  O O   . ILE A 1 197 ? 116.884 114.953 106.709 1.00 285.13 ?  197  ILE A O   1 
ATOM   642  C CB  . ILE A 1 197 ? 115.615 112.673 108.753 1.00 285.13 ?  197  ILE A CB  1 
ATOM   643  C CG1 . ILE A 1 197 ? 115.050 111.259 108.642 1.00 285.13 ?  197  ILE A CG1 1 
ATOM   644  C CG2 . ILE A 1 197 ? 114.526 113.677 108.416 1.00 285.13 ?  197  ILE A CG2 1 
ATOM   645  C CD1 . ILE A 1 197 ? 113.554 111.181 108.842 1.00 285.13 ?  197  ILE A CD1 1 
ATOM   646  N N   . LEU A 1 198 ? 117.948 114.821 108.676 1.00 250.77 ?  198  LEU A N   1 
ATOM   647  C CA  . LEU A 1 198 ? 118.357 116.219 108.644 1.00 250.77 ?  198  LEU A CA  1 
ATOM   648  C C   . LEU A 1 198 ? 119.312 116.495 107.493 1.00 250.77 ?  198  LEU A C   1 
ATOM   649  O O   . LEU A 1 198 ? 119.437 117.635 107.052 1.00 250.77 ?  198  LEU A O   1 
ATOM   650  C CB  . LEU A 1 198 ? 119.003 116.622 109.970 1.00 250.77 ?  198  LEU A CB  1 
ATOM   651  C CG  . LEU A 1 198 ? 118.181 117.513 110.900 1.00 250.77 ?  198  LEU A CG  1 
ATOM   652  C CD1 . LEU A 1 198 ? 116.773 117.683 110.359 1.00 250.77 ?  198  LEU A CD1 1 
ATOM   653  C CD2 . LEU A 1 198 ? 118.151 116.946 112.309 1.00 250.77 ?  198  LEU A CD2 1 
ATOM   654  N N   . ARG A 1 199 ? 119.985 115.461 106.998 1.00 291.37 ?  199  ARG A N   1 
ATOM   655  C CA  . ARG A 1 199 ? 120.900 115.624 105.871 1.00 291.37 ?  199  ARG A CA  1 
ATOM   656  C C   . ARG A 1 199 ? 120.167 115.435 104.557 1.00 291.37 ?  199  ARG A C   1 
ATOM   657  O O   . ARG A 1 199 ? 120.781 115.118 103.542 1.00 291.37 ?  199  ARG A O   1 
ATOM   658  C CB  . ARG A 1 199 ? 122.063 114.634 105.972 1.00 291.37 ?  199  ARG A CB  1 
ATOM   659  C CG  . ARG A 1 199 ? 123.435 115.251 105.755 1.00 291.37 ?  199  ARG A CG  1 
ATOM   660  C CD  . ARG A 1 199 ? 124.234 115.295 107.046 1.00 291.37 ?  199  ARG A CD  1 
ATOM   661  N NE  . ARG A 1 199 ? 123.366 115.419 108.213 1.00 291.37 ?  199  ARG A NE  1 
ATOM   662  C CZ  . ARG A 1 199 ? 123.798 115.601 109.455 1.00 291.37 ?  199  ARG A CZ  1 
ATOM   663  N NH1 . ARG A 1 199 ? 125.096 115.677 109.708 1.00 291.37 1  199  ARG A NH1 1 
ATOM   664  N NH2 . ARG A 1 199 ? 122.928 115.702 110.445 1.00 291.37 ?  199  ARG A NH2 1 
ATOM   665  N N   . GLY A 1 200 ? 118.852 115.610 104.571 1.00 276.46 ?  200  GLY A N   1 
ATOM   666  C CA  . GLY A 1 200 ? 118.079 115.506 103.349 1.00 276.46 ?  200  GLY A CA  1 
ATOM   667  C C   . GLY A 1 200 ? 117.413 114.172 103.122 1.00 276.46 ?  200  GLY A C   1 
ATOM   668  O O   . GLY A 1 200 ? 116.292 114.125 102.621 1.00 276.46 ?  200  GLY A O   1 
ATOM   669  N N   . VAL A 1 201 ? 118.081 113.082 103.481 1.00 264.22 ?  201  VAL A N   1 
ATOM   670  C CA  . VAL A 1 201 ? 117.529 111.761 103.196 1.00 264.22 ?  201  VAL A CA  1 
ATOM   671  C C   . VAL A 1 201 ? 116.398 111.357 104.121 1.00 264.22 ?  201  VAL A C   1 
ATOM   672  O O   . VAL A 1 201 ? 116.631 110.770 105.173 1.00 264.22 ?  201  VAL A O   1 
ATOM   673  C CB  . VAL A 1 201 ? 118.608 110.672 103.231 1.00 264.22 ?  201  VAL A CB  1 
ATOM   674  C CG1 . VAL A 1 201 ? 118.502 109.799 101.992 1.00 264.22 ?  201  VAL A CG1 1 
ATOM   675  C CG2 . VAL A 1 201 ? 119.988 111.297 103.331 1.00 264.22 ?  201  VAL A CG2 1 
ATOM   676  N N   . VAL A 1 202 ? 115.168 111.651 103.720 1.00 240.15 ?  202  VAL A N   1 
ATOM   677  C CA  . VAL A 1 202 ? 114.019 111.262 104.521 1.00 240.15 ?  202  VAL A CA  1 
ATOM   678  C C   . VAL A 1 202 ? 113.896 109.741 104.530 1.00 240.15 ?  202  VAL A C   1 
ATOM   679  O O   . VAL A 1 202 ? 114.222 109.076 103.545 1.00 240.15 ?  202  VAL A O   1 
ATOM   680  C CB  . VAL A 1 202 ? 112.726 111.949 104.024 1.00 240.15 ?  202  VAL A CB  1 
ATOM   681  C CG1 . VAL A 1 202 ? 112.283 111.406 102.673 1.00 240.15 ?  202  VAL A CG1 1 
ATOM   682  C CG2 . VAL A 1 202 ? 111.615 111.850 105.059 1.00 240.15 ?  202  VAL A CG2 1 
ATOM   683  N N   . LEU A 1 203 ? 113.457 109.178 105.649 1.00 252.28 ?  203  LEU A N   1 
ATOM   684  C CA  . LEU A 1 203 ? 113.362 107.728 105.754 1.00 252.28 ?  203  LEU A CA  1 
ATOM   685  C C   . LEU A 1 203 ? 111.995 107.234 105.321 1.00 252.28 ?  203  LEU A C   1 
ATOM   686  O O   . LEU A 1 203 ? 111.298 107.914 104.570 1.00 252.28 ?  203  LEU A O   1 
ATOM   687  C CB  . LEU A 1 203 ? 113.683 107.270 107.176 1.00 252.28 ?  203  LEU A CB  1 
ATOM   688  C CG  . LEU A 1 203 ? 115.099 106.729 107.385 1.00 252.28 ?  203  LEU A CG  1 
ATOM   689  C CD1 . LEU A 1 203 ? 115.799 106.508 106.053 1.00 252.28 ?  203  LEU A CD1 1 
ATOM   690  C CD2 . LEU A 1 203 ? 115.913 107.664 108.262 1.00 252.28 ?  203  LEU A CD2 1 
ATOM   691  N N   . LYS A 1 204 ? 111.610 106.050 105.779 1.00 266.35 ?  204  LYS A N   1 
ATOM   692  C CA  . LYS A 1 204 ? 110.330 105.479 105.372 1.00 266.35 ?  204  LYS A CA  1 
ATOM   693  C C   . LYS A 1 204 ? 109.183 106.060 106.174 1.00 266.35 ?  204  LYS A C   1 
ATOM   694  O O   . LYS A 1 204 ? 108.752 107.187 105.936 1.00 266.35 ?  204  LYS A O   1 
ATOM   695  C CB  . LYS A 1 204 ? 110.349 103.961 105.534 1.00 266.35 ?  204  LYS A CB  1 
ATOM   696  C CG  . LYS A 1 204 ? 109.867 103.202 104.308 1.00 266.35 ?  204  LYS A CG  1 
ATOM   697  C CD  . LYS A 1 204 ? 110.056 104.024 103.043 1.00 266.35 ?  204  LYS A CD  1 
ATOM   698  C CE  . LYS A 1 204 ? 110.938 103.299 102.039 1.00 266.35 ?  204  LYS A CE  1 
ATOM   699  N NZ  . LYS A 1 204 ? 112.327 103.118 102.543 1.00 266.35 1  204  LYS A NZ  1 
ATOM   700  N N   . GLU A 1 205 ? 108.674 105.286 107.122 1.00 287.44 ?  205  GLU A N   1 
ATOM   701  C CA  . GLU A 1 205 ? 107.602 105.780 107.969 1.00 287.44 ?  205  GLU A CA  1 
ATOM   702  C C   . GLU A 1 205 ? 108.182 106.148 109.319 1.00 287.44 ?  205  GLU A C   1 
ATOM   703  O O   . GLU A 1 205 ? 107.643 105.773 110.358 1.00 287.44 ?  205  GLU A O   1 
ATOM   704  C CB  . GLU A 1 205 ? 106.507 104.727 108.116 1.00 287.44 ?  205  GLU A CB  1 
ATOM   705  C CG  . GLU A 1 205 ? 106.373 103.797 106.922 1.00 287.44 ?  205  GLU A CG  1 
ATOM   706  C CD  . GLU A 1 205 ? 105.741 104.476 105.724 1.00 287.44 ?  205  GLU A CD  1 
ATOM   707  O OE1 . GLU A 1 205 ? 104.639 105.046 105.874 1.00 287.44 ?  205  GLU A OE1 1 
ATOM   708  O OE2 . GLU A 1 205 ? 106.347 104.442 104.632 1.00 287.44 -1 205  GLU A OE2 1 
ATOM   709  N N   . TYR A 1 206 ? 109.286 106.885 109.308 1.00 270.14 ?  206  TYR A N   1 
ATOM   710  C CA  . TYR A 1 206 ? 109.941 107.255 110.551 1.00 270.14 ?  206  TYR A CA  1 
ATOM   711  C C   . TYR A 1 206 ? 109.156 108.283 111.344 1.00 270.14 ?  206  TYR A C   1 
ATOM   712  O O   . TYR A 1 206 ? 108.885 108.078 112.522 1.00 270.14 ?  206  TYR A O   1 
ATOM   713  C CB  . TYR A 1 206 ? 111.346 107.782 110.271 1.00 270.14 ?  206  TYR A CB  1 
ATOM   714  C CG  . TYR A 1 206 ? 112.303 107.504 111.395 1.00 270.14 ?  206  TYR A CG  1 
ATOM   715  C CD1 . TYR A 1 206 ? 112.464 106.217 111.880 1.00 270.14 ?  206  TYR A CD1 1 
ATOM   716  C CD2 . TYR A 1 206 ? 113.032 108.524 111.982 1.00 270.14 ?  206  TYR A CD2 1 
ATOM   717  C CE1 . TYR A 1 206 ? 113.332 105.951 112.916 1.00 270.14 ?  206  TYR A CE1 1 
ATOM   718  C CE2 . TYR A 1 206 ? 113.903 108.268 113.022 1.00 270.14 ?  206  TYR A CE2 1 
ATOM   719  C CZ  . TYR A 1 206 ? 114.044 106.977 113.484 1.00 270.14 ?  206  TYR A CZ  1 
ATOM   720  O OH  . TYR A 1 206 ? 114.904 106.701 114.516 1.00 270.14 ?  206  TYR A OH  1 
ATOM   721  N N   . LEU A 1 207 ? 108.780 109.386 110.710 1.00 249.20 ?  207  LEU A N   1 
ATOM   722  C CA  . LEU A 1 207 ? 108.084 110.451 111.425 1.00 249.20 ?  207  LEU A CA  1 
ATOM   723  C C   . LEU A 1 207 ? 106.574 110.316 111.333 1.00 249.20 ?  207  LEU A C   1 
ATOM   724  O O   . LEU A 1 207 ? 105.884 111.288 111.040 1.00 249.20 ?  207  LEU A O   1 
ATOM   725  C CB  . LEU A 1 207 ? 108.507 111.814 110.884 1.00 249.20 ?  207  LEU A CB  1 
ATOM   726  C CG  . LEU A 1 207 ? 109.546 112.612 111.670 1.00 249.20 ?  207  LEU A CG  1 
ATOM   727  C CD1 . LEU A 1 207 ? 110.240 111.741 112.701 1.00 249.20 ?  207  LEU A CD1 1 
ATOM   728  C CD2 . LEU A 1 207 ? 110.560 113.229 110.722 1.00 249.20 ?  207  LEU A CD2 1 
ATOM   729  N N   . THR A 1 208 ? 106.056 109.121 111.588 1.00 277.04 ?  208  THR A N   1 
ATOM   730  C CA  . THR A 1 208 ? 104.620 108.895 111.510 1.00 277.04 ?  208  THR A CA  1 
ATOM   731  C C   . THR A 1 208 ? 103.997 108.754 112.887 1.00 277.04 ?  208  THR A C   1 
ATOM   732  O O   . THR A 1 208 ? 104.708 108.659 113.883 1.00 277.04 ?  208  THR A O   1 
ATOM   733  C CB  . THR A 1 208 ? 104.289 107.642 110.688 1.00 277.04 ?  208  THR A CB  1 
ATOM   734  O OG1 . THR A 1 208 ? 105.065 106.536 111.163 1.00 277.04 ?  208  THR A OG1 1 
ATOM   735  C CG2 . THR A 1 208 ? 104.590 107.879 109.220 1.00 277.04 ?  208  THR A CG2 1 
ATOM   736  N N   . MET A 1 209 ? 102.670 108.731 112.946 1.00 249.61 ?  209  MET A N   1 
ATOM   737  C CA  . MET A 1 209 ? 101.978 108.631 114.225 1.00 249.61 ?  209  MET A CA  1 
ATOM   738  C C   . MET A 1 209 ? 102.053 107.230 114.833 1.00 249.61 ?  209  MET A C   1 
ATOM   739  O O   . MET A 1 209 ? 102.021 107.094 116.054 1.00 249.61 ?  209  MET A O   1 
ATOM   740  C CB  . MET A 1 209 ? 100.522 109.078 114.097 1.00 249.61 ?  209  MET A CB  1 
ATOM   741  C CG  . MET A 1 209 ? 100.242 110.455 114.671 1.00 249.61 ?  209  MET A CG  1 
ATOM   742  S SD  . MET A 1 209 ? 101.153 110.798 116.188 1.00 249.61 ?  209  MET A SD  1 
ATOM   743  C CE  . MET A 1 209 ? 100.025 110.150 117.419 1.00 249.61 ?  209  MET A CE  1 
ATOM   744  N N   . LYS A 1 210 ? 102.152 106.187 114.006 1.00 257.56 ?  210  LYS A N   1 
ATOM   745  C CA  . LYS A 1 210 ? 102.313 104.843 114.559 1.00 257.56 ?  210  LYS A CA  1 
ATOM   746  C C   . LYS A 1 210 ? 103.640 104.756 115.271 1.00 257.56 ?  210  LYS A C   1 
ATOM   747  O O   . LYS A 1 210 ? 103.749 104.153 116.339 1.00 257.56 ?  210  LYS A O   1 
ATOM   748  C CB  . LYS A 1 210 ? 102.241 103.737 113.504 1.00 257.56 ?  210  LYS A CB  1 
ATOM   749  C CG  . LYS A 1 210 ? 101.978 104.162 112.076 1.00 257.56 ?  210  LYS A CG  1 
ATOM   750  C CD  . LYS A 1 210 ? 101.322 103.021 111.319 1.00 257.56 ?  210  LYS A CD  1 
ATOM   751  C CE  . LYS A 1 210 ? 99.915  102.788 111.831 1.00 257.56 ?  210  LYS A CE  1 
ATOM   752  N NZ  . LYS A 1 210 ? 99.305  101.492 111.411 1.00 257.56 1  210  LYS A NZ  1 
ATOM   753  N N   . ALA A 1 211 ? 104.657 105.372 114.689 1.00 269.25 ?  211  ALA A N   1 
ATOM   754  C CA  . ALA A 1 211 ? 105.972 105.330 115.289 1.00 269.25 ?  211  ALA A CA  1 
ATOM   755  C C   . ALA A 1 211 ? 105.907 105.985 116.643 1.00 269.25 ?  211  ALA A C   1 
ATOM   756  O O   . ALA A 1 211 ? 106.512 105.500 117.588 1.00 269.25 ?  211  ALA A O   1 
ATOM   757  C CB  . ALA A 1 211 ? 106.983 106.019 114.396 1.00 269.25 ?  211  ALA A CB  1 
ATOM   758  N N   . PHE A 1 212 ? 105.165 107.082 116.750 1.00 256.48 ?  212  PHE A N   1 
ATOM   759  C CA  . PHE A 1 212 ? 105.004 107.756 118.029 1.00 256.48 ?  212  PHE A CA  1 
ATOM   760  C C   . PHE A 1 212 ? 104.464 106.785 119.051 1.00 256.48 ?  212  PHE A C   1 
ATOM   761  O O   . PHE A 1 212 ? 105.108 106.531 120.058 1.00 256.48 ?  212  PHE A O   1 
ATOM   762  C CB  . PHE A 1 212 ? 104.053 108.938 117.893 1.00 256.48 ?  212  PHE A CB  1 
ATOM   763  C CG  . PHE A 1 212 ? 104.083 109.881 119.057 1.00 256.48 ?  212  PHE A CG  1 
ATOM   764  C CD1 . PHE A 1 212 ? 105.101 110.808 119.186 1.00 256.48 ?  212  PHE A CD1 1 
ATOM   765  C CD2 . PHE A 1 212 ? 103.087 109.849 120.017 1.00 256.48 ?  212  PHE A CD2 1 
ATOM   766  C CE1 . PHE A 1 212 ? 105.128 111.682 120.252 1.00 256.48 ?  212  PHE A CE1 1 
ATOM   767  C CE2 . PHE A 1 212 ? 103.109 110.718 121.088 1.00 256.48 ?  212  PHE A CE2 1 
ATOM   768  C CZ  . PHE A 1 212 ? 104.132 111.637 121.205 1.00 256.48 ?  212  PHE A CZ  1 
ATOM   769  N N   . VAL A 1 213 ? 103.285 106.233 118.790 1.00 248.50 ?  213  VAL A N   1 
ATOM   770  C CA  . VAL A 1 213 ? 102.675 105.291 119.721 1.00 248.50 ?  213  VAL A CA  1 
ATOM   771  C C   . VAL A 1 213 ? 103.644 104.180 120.093 1.00 248.50 ?  213  VAL A C   1 
ATOM   772  O O   . VAL A 1 213 ? 103.898 103.946 121.270 1.00 248.50 ?  213  VAL A O   1 
ATOM   773  C CB  . VAL A 1 213 ? 101.385 104.687 119.144 1.00 248.50 ?  213  VAL A CB  1 
ATOM   774  C CG1 . VAL A 1 213 ? 100.709 103.790 120.167 1.00 248.50 ?  213  VAL A CG1 1 
ATOM   775  C CG2 . VAL A 1 213 ? 100.441 105.793 118.705 1.00 248.50 ?  213  VAL A CG2 1 
ATOM   776  N N   . ALA A 1 214 ? 104.200 103.505 119.093 1.00 277.83 ?  214  ALA A N   1 
ATOM   777  C CA  . ALA A 1 214 ? 105.136 102.422 119.353 1.00 277.83 ?  214  ALA A CA  1 
ATOM   778  C C   . ALA A 1 214 ? 106.246 102.875 120.273 1.00 277.83 ?  214  ALA A C   1 
ATOM   779  O O   . ALA A 1 214 ? 106.429 102.309 121.342 1.00 277.83 ?  214  ALA A O   1 
ATOM   780  C CB  . ALA A 1 214 ? 105.711 101.891 118.056 1.00 277.83 ?  214  ALA A CB  1 
ATOM   781  N N   . LYS A 1 215 ? 106.977 103.906 119.875 1.00 263.72 ?  215  LYS A N   1 
ATOM   782  C CA  . LYS A 1 215 ? 108.102 104.363 120.674 1.00 263.72 ?  215  LYS A CA  1 
ATOM   783  C C   . LYS A 1 215 ? 107.708 104.761 122.085 1.00 263.72 ?  215  LYS A C   1 
ATOM   784  O O   . LYS A 1 215 ? 108.333 104.318 123.031 1.00 263.72 ?  215  LYS A O   1 
ATOM   785  C CB  . LYS A 1 215 ? 108.842 105.506 119.987 1.00 263.72 ?  215  LYS A CB  1 
ATOM   786  C CG  . LYS A 1 215 ? 110.323 105.553 120.313 1.00 263.72 ?  215  LYS A CG  1 
ATOM   787  C CD  . LYS A 1 215 ? 111.147 105.689 119.049 1.00 263.72 ?  215  LYS A CD  1 
ATOM   788  C CE  . LYS A 1 215 ? 112.526 105.074 119.205 1.00 263.72 ?  215  LYS A CE  1 
ATOM   789  N NZ  . LYS A 1 215 ? 113.106 104.694 117.891 1.00 263.72 1  215  LYS A NZ  1 
ATOM   790  N N   . VAL A 1 216 ? 106.678 105.583 122.247 1.00 243.99 ?  216  VAL A N   1 
ATOM   791  C CA  . VAL A 1 216 ? 106.345 106.052 123.590 1.00 243.99 ?  216  VAL A CA  1 
ATOM   792  C C   . VAL A 1 216 ? 105.997 104.901 124.524 1.00 243.99 ?  216  VAL A C   1 
ATOM   793  O O   . VAL A 1 216 ? 106.534 104.819 125.621 1.00 243.99 ?  216  VAL A O   1 
ATOM   794  C CB  . VAL A 1 216 ? 105.270 107.175 123.621 1.00 243.99 ?  216  VAL A CB  1 
ATOM   795  C CG1 . VAL A 1 216 ? 105.736 108.386 122.834 1.00 243.99 ?  216  VAL A CG1 1 
ATOM   796  C CG2 . VAL A 1 216 ? 103.911 106.706 123.130 1.00 243.99 ?  216  VAL A CG2 1 
ATOM   797  N N   . VAL A 1 217 ? 105.140 103.990 124.085 1.00 240.87 ?  217  VAL A N   1 
ATOM   798  C CA  . VAL A 1 217 ? 104.713 102.904 124.949 1.00 240.87 ?  217  VAL A CA  1 
ATOM   799  C C   . VAL A 1 217 ? 105.868 101.963 125.212 1.00 240.87 ?  217  VAL A C   1 
ATOM   800  O O   . VAL A 1 217 ? 106.131 101.592 126.355 1.00 240.87 ?  217  VAL A O   1 
ATOM   801  C CB  . VAL A 1 217 ? 103.529 102.140 124.337 1.00 240.87 ?  217  VAL A CB  1 
ATOM   802  C CG1 . VAL A 1 217 ? 103.090 101.009 125.250 1.00 240.87 ?  217  VAL A CG1 1 
ATOM   803  C CG2 . VAL A 1 217 ? 102.367 103.088 124.090 1.00 240.87 ?  217  VAL A CG2 1 
ATOM   804  N N   . ALA A 1 218 ? 106.584 101.599 124.161 1.00 248.37 ?  218  ALA A N   1 
ATOM   805  C CA  . ALA A 1 218 ? 107.695 100.674 124.311 1.00 248.37 ?  218  ALA A CA  1 
ATOM   806  C C   . ALA A 1 218 ? 108.860 101.252 125.104 1.00 248.37 ?  218  ALA A C   1 
ATOM   807  O O   . ALA A 1 218 ? 109.542 100.520 125.813 1.00 248.37 ?  218  ALA A O   1 
ATOM   808  C CB  . ALA A 1 218 ? 108.151 100.187 122.955 1.00 248.37 ?  218  ALA A CB  1 
ATOM   809  N N   . LEU A 1 219 ? 109.093 102.554 125.006 1.00 254.00 ?  219  LEU A N   1 
ATOM   810  C CA  . LEU A 1 219 ? 110.145 103.167 125.804 1.00 254.00 ?  219  LEU A CA  1 
ATOM   811  C C   . LEU A 1 219 ? 109.739 103.215 127.264 1.00 254.00 ?  219  LEU A C   1 
ATOM   812  O O   . LEU A 1 219 ? 110.559 102.972 128.134 1.00 254.00 ?  219  LEU A O   1 
ATOM   813  C CB  . LEU A 1 219 ? 110.484 104.567 125.307 1.00 254.00 ?  219  LEU A CB  1 
ATOM   814  C CG  . LEU A 1 219 ? 111.961 104.950 125.224 1.00 254.00 ?  219  LEU A CG  1 
ATOM   815  C CD1 . LEU A 1 219 ? 112.211 106.278 125.914 1.00 254.00 ?  219  LEU A CD1 1 
ATOM   816  C CD2 . LEU A 1 219 ? 112.873 103.872 125.786 1.00 254.00 ?  219  LEU A CD2 1 
ATOM   817  N N   . THR A 1 220 ? 108.477 103.520 127.544 1.00 260.38 ?  220  THR A N   1 
ATOM   818  C CA  . THR A 1 220 ? 108.005 103.516 128.920 1.00 260.38 ?  220  THR A CA  1 
ATOM   819  C C   . THR A 1 220 ? 108.257 102.151 129.530 1.00 260.38 ?  220  THR A C   1 
ATOM   820  O O   . THR A 1 220 ? 108.749 102.044 130.652 1.00 260.38 ?  220  THR A O   1 
ATOM   821  C CB  . THR A 1 220 ? 106.503 103.826 129.008 1.00 260.38 ?  220  THR A CB  1 
ATOM   822  O OG1 . THR A 1 220 ? 106.208 105.011 128.263 1.00 260.38 ?  220  THR A OG1 1 
ATOM   823  C CG2 . THR A 1 220 ? 106.090 104.034 130.440 1.00 260.38 ?  220  THR A CG2 1 
ATOM   824  N N   . ALA A 1 221 ? 107.936 101.099 128.787 1.00 244.81 ?  221  ALA A N   1 
ATOM   825  C CA  . ALA A 1 221 ? 108.128 99.748  129.288 1.00 244.81 ?  221  ALA A CA  1 
ATOM   826  C C   . ALA A 1 221 ? 109.599 99.434  129.487 1.00 244.81 ?  221  ALA A C   1 
ATOM   827  O O   . ALA A 1 221 ? 109.973 98.814  130.475 1.00 244.81 ?  221  ALA A O   1 
ATOM   828  C CB  . ALA A 1 221 ? 107.491 98.749  128.344 1.00 244.81 ?  221  ALA A CB  1 
ATOM   829  N N   . GLY A 1 222 ? 110.441 99.869  128.560 1.00 244.62 ?  222  GLY A N   1 
ATOM   830  C CA  . GLY A 1 222 ? 111.867 99.643  128.685 1.00 244.62 ?  222  GLY A CA  1 
ATOM   831  C C   . GLY A 1 222 ? 112.495 100.405 129.830 1.00 244.62 ?  222  GLY A C   1 
ATOM   832  O O   . GLY A 1 222 ? 113.475 99.953  130.412 1.00 244.62 ?  222  GLY A O   1 
ATOM   833  N N   . LEU A 1 223 ? 111.938 101.562 130.162 1.00 242.33 ?  223  LEU A N   1 
ATOM   834  C CA  . LEU A 1 223 ? 112.477 102.374 131.246 1.00 242.33 ?  223  LEU A CA  1 
ATOM   835  C C   . LEU A 1 223 ? 111.953 101.924 132.597 1.00 242.33 ?  223  LEU A C   1 
ATOM   836  O O   . LEU A 1 223 ? 112.507 102.288 133.628 1.00 242.33 ?  223  LEU A O   1 
ATOM   837  C CB  . LEU A 1 223 ? 112.146 103.847 131.031 1.00 242.33 ?  223  LEU A CB  1 
ATOM   838  C CG  . LEU A 1 223 ? 112.830 104.588 129.887 1.00 242.33 ?  223  LEU A CG  1 
ATOM   839  C CD1 . LEU A 1 223 ? 112.132 105.920 129.678 1.00 242.33 ?  223  LEU A CD1 1 
ATOM   840  C CD2 . LEU A 1 223 ? 114.310 104.785 130.170 1.00 242.33 ?  223  LEU A CD2 1 
ATOM   841  N N   . GLY A 1 224 ? 110.889 101.135 132.599 1.00 257.32 ?  224  GLY A N   1 
ATOM   842  C CA  . GLY A 1 224 ? 110.343 100.632 133.842 1.00 257.32 ?  224  GLY A CA  1 
ATOM   843  C C   . GLY A 1 224 ? 110.755 99.203  134.096 1.00 257.32 ?  224  GLY A C   1 
ATOM   844  O O   . GLY A 1 224 ? 110.213 98.543  134.976 1.00 257.32 ?  224  GLY A O   1 
ATOM   845  N N   . SER A 1 225 ? 111.720 98.715  133.329 1.00 236.65 ?  225  SER A N   1 
ATOM   846  C CA  . SER A 1 225 ? 112.182 97.346  133.491 1.00 236.65 ?  225  SER A CA  1 
ATOM   847  C C   . SER A 1 225 ? 113.433 97.290  134.345 1.00 236.65 ?  225  SER A C   1 
ATOM   848  O O   . SER A 1 225 ? 113.646 96.327  135.074 1.00 236.65 ?  225  SER A O   1 
ATOM   849  C CB  . SER A 1 225 ? 112.457 96.725  132.128 1.00 236.65 ?  225  SER A CB  1 
ATOM   850  O OG  . SER A 1 225 ? 113.492 97.415  131.458 1.00 236.65 ?  225  SER A OG  1 
ATOM   851  N N   . GLY A 1 226 ? 114.266 98.321  134.262 1.00 225.32 ?  226  GLY A N   1 
ATOM   852  C CA  . GLY A 1 226 ? 115.508 98.332  135.010 1.00 225.32 ?  226  GLY A CA  1 
ATOM   853  C C   . GLY A 1 226 ? 116.656 97.881  134.141 1.00 225.32 ?  226  GLY A C   1 
ATOM   854  O O   . GLY A 1 226 ? 117.814 97.984  134.536 1.00 225.32 ?  226  GLY A O   1 
ATOM   855  N N   . ILE A 1 227 ? 116.343 97.374  132.955 1.00 196.92 ?  227  ILE A N   1 
ATOM   856  C CA  . ILE A 1 227 ? 117.370 96.933  132.026 1.00 196.92 ?  227  ILE A CA  1 
ATOM   857  C C   . ILE A 1 227 ? 118.028 98.196  131.513 1.00 196.92 ?  227  ILE A C   1 
ATOM   858  O O   . ILE A 1 227 ? 117.334 99.164  131.218 1.00 196.92 ?  227  ILE A O   1 
ATOM   859  C CB  . ILE A 1 227 ? 116.740 96.117  130.879 1.00 196.92 ?  227  ILE A CB  1 
ATOM   860  C CG1 . ILE A 1 227 ? 116.036 94.884  131.443 1.00 196.92 ?  227  ILE A CG1 1 
ATOM   861  C CG2 . ILE A 1 227 ? 117.777 95.688  129.855 1.00 196.92 ?  227  ILE A CG2 1 
ATOM   862  C CD1 . ILE A 1 227 ? 116.942 93.981  132.250 1.00 196.92 ?  227  ILE A CD1 1 
ATOM   863  N N   . PRO A 1 228 ? 119.394 98.227  131.432 1.00 174.25 ?  228  PRO A N   1 
ATOM   864  C CA  . PRO A 1 228 ? 119.976 99.513  131.020 1.00 174.25 ?  228  PRO A CA  1 
ATOM   865  C C   . PRO A 1 228 ? 119.717 99.921  129.580 1.00 174.25 ?  228  PRO A C   1 
ATOM   866  O O   . PRO A 1 228 ? 120.579 99.735  128.726 1.00 174.25 ?  228  PRO A O   1 
ATOM   867  C CB  . PRO A 1 228 ? 121.475 99.312  131.253 1.00 174.25 ?  228  PRO A CB  1 
ATOM   868  C CG  . PRO A 1 228 ? 121.685 97.847  131.154 1.00 174.25 ?  228  PRO A CG  1 
ATOM   869  C CD  . PRO A 1 228 ? 120.464 97.257  131.778 1.00 174.25 ?  228  PRO A CD  1 
ATOM   870  N N   . VAL A 1 229 ? 118.547 100.481 129.308 1.00 202.83 ?  229  VAL A N   1 
ATOM   871  C CA  . VAL A 1 229 ? 118.251 100.977 127.974 1.00 202.83 ?  229  VAL A CA  1 
ATOM   872  C C   . VAL A 1 229 ? 118.262 102.488 128.095 1.00 202.83 ?  229  VAL A C   1 
ATOM   873  O O   . VAL A 1 229 ? 118.187 103.027 129.201 1.00 202.83 ?  229  VAL A O   1 
ATOM   874  C CB  . VAL A 1 229 ? 116.893 100.466 127.459 1.00 202.83 ?  229  VAL A CB  1 
ATOM   875  C CG1 . VAL A 1 229 ? 116.754 98.979  127.740 1.00 202.83 ?  229  VAL A CG1 1 
ATOM   876  C CG2 . VAL A 1 229 ? 115.741 101.238 128.081 1.00 202.83 ?  229  VAL A CG2 1 
ATOM   877  N N   . GLY A 1 230 ? 118.383 103.187 126.979 1.00 199.38 ?  230  GLY A N   1 
ATOM   878  C CA  . GLY A 1 230 ? 118.475 104.628 127.045 1.00 199.38 ?  230  GLY A CA  1 
ATOM   879  C C   . GLY A 1 230 ? 117.157 105.334 126.889 1.00 199.38 ?  230  GLY A C   1 
ATOM   880  O O   . GLY A 1 230 ? 116.124 104.700 126.700 1.00 199.38 ?  230  GLY A O   1 
ATOM   881  N N   . LYS A 1 231 ? 117.189 106.655 126.960 1.00 223.11 ?  231  LYS A N   1 
ATOM   882  C CA  . LYS A 1 231 ? 115.974 107.435 126.836 1.00 223.11 ?  231  LYS A CA  1 
ATOM   883  C C   . LYS A 1 231 ? 116.233 108.561 125.858 1.00 223.11 ?  231  LYS A C   1 
ATOM   884  O O   . LYS A 1 231 ? 115.369 108.891 125.057 1.00 223.11 ?  231  LYS A O   1 
ATOM   885  C CB  . LYS A 1 231 ? 115.591 107.993 128.206 1.00 223.11 ?  231  LYS A CB  1 
ATOM   886  C CG  . LYS A 1 231 ? 114.275 108.746 128.246 1.00 223.11 ?  231  LYS A CG  1 
ATOM   887  C CD  . LYS A 1 231 ? 114.051 109.380 129.608 1.00 223.11 ?  231  LYS A CD  1 
ATOM   888  C CE  . LYS A 1 231 ? 115.193 109.066 130.559 1.00 223.11 ?  231  LYS A CE  1 
ATOM   889  N NZ  . LYS A 1 231 ? 115.531 110.234 131.419 1.00 223.11 1  231  LYS A NZ  1 
ATOM   890  N N   . GLU A 1 232 ? 117.433 109.132 125.898 1.00 245.05 ?  232  GLU A N   1 
ATOM   891  C CA  . GLU A 1 232 ? 117.773 110.263 125.030 1.00 245.05 ?  232  GLU A CA  1 
ATOM   892  C C   . GLU A 1 232 ? 117.504 110.032 123.552 1.00 245.05 ?  232  GLU A C   1 
ATOM   893  O O   . GLU A 1 232 ? 116.865 110.858 122.901 1.00 245.05 ?  232  GLU A O   1 
ATOM   894  C CB  . GLU A 1 232 ? 119.232 110.666 125.248 1.00 245.05 ?  232  GLU A CB  1 
ATOM   895  C CG  . GLU A 1 232 ? 119.939 111.247 124.040 1.00 245.05 ?  232  GLU A CG  1 
ATOM   896  C CD  . GLU A 1 232 ? 121.106 110.394 123.604 1.00 245.05 ?  232  GLU A CD  1 
ATOM   897  O OE1 . GLU A 1 232 ? 120.901 109.443 122.823 1.00 245.05 ?  232  GLU A OE1 1 
ATOM   898  O OE2 . GLU A 1 232 ? 122.234 110.673 124.049 1.00 245.05 -1 232  GLU A OE2 1 
ATOM   899  N N   . GLY A 1 233 ? 117.989 108.919 123.017 1.00 234.26 ?  233  GLY A N   1 
ATOM   900  C CA  . GLY A 1 233 ? 117.798 108.647 121.609 1.00 234.26 ?  233  GLY A CA  1 
ATOM   901  C C   . GLY A 1 233 ? 116.354 108.558 121.180 1.00 234.26 ?  233  GLY A C   1 
ATOM   902  O O   . GLY A 1 233 ? 115.921 109.313 120.315 1.00 234.26 ?  233  GLY A O   1 
ATOM   903  N N   . PRO A 1 234 ? 115.600 107.619 121.767 1.00 242.17 ?  234  PRO A N   1 
ATOM   904  C CA  . PRO A 1 234 ? 114.178 107.532 121.443 1.00 242.17 ?  234  PRO A CA  1 
ATOM   905  C C   . PRO A 1 234 ? 113.449 108.851 121.625 1.00 242.17 ?  234  PRO A C   1 
ATOM   906  O O   . PRO A 1 234 ? 112.575 109.160 120.831 1.00 242.17 ?  234  PRO A O   1 
ATOM   907  C CB  . PRO A 1 234 ? 113.670 106.518 122.455 1.00 242.17 ?  234  PRO A CB  1 
ATOM   908  C CG  . PRO A 1 234 ? 114.827 105.610 122.666 1.00 242.17 ?  234  PRO A CG  1 
ATOM   909  C CD  . PRO A 1 234 ? 116.042 106.484 122.596 1.00 242.17 ?  234  PRO A CD  1 
ATOM   910  N N   . PHE A 1 235 ? 113.802 109.614 122.649 1.00 250.74 ?  235  PHE A N   1 
ATOM   911  C CA  . PHE A 1 235 ? 113.148 110.888 122.921 1.00 250.74 ?  235  PHE A CA  1 
ATOM   912  C C   . PHE A 1 235 ? 113.344 111.885 121.796 1.00 250.74 ?  235  PHE A C   1 
ATOM   913  O O   . PHE A 1 235 ? 112.424 112.612 121.458 1.00 250.74 ?  235  PHE A O   1 
ATOM   914  C CB  . PHE A 1 235 ? 113.642 111.480 124.236 1.00 250.74 ?  235  PHE A CB  1 
ATOM   915  C CG  . PHE A 1 235 ? 112.729 111.216 125.393 1.00 250.74 ?  235  PHE A CG  1 
ATOM   916  C CD1 . PHE A 1 235 ? 111.991 110.051 125.456 1.00 250.74 ?  235  PHE A CD1 1 
ATOM   917  C CD2 . PHE A 1 235 ? 112.602 112.135 126.413 1.00 250.74 ?  235  PHE A CD2 1 
ATOM   918  C CE1 . PHE A 1 235 ? 111.149 109.805 126.520 1.00 250.74 ?  235  PHE A CE1 1 
ATOM   919  C CE2 . PHE A 1 235 ? 111.765 111.895 127.482 1.00 250.74 ?  235  PHE A CE2 1 
ATOM   920  C CZ  . PHE A 1 235 ? 111.033 110.729 127.536 1.00 250.74 ?  235  PHE A CZ  1 
ATOM   921  N N   . VAL A 1 236 ? 114.537 111.931 121.216 1.00 259.83 ?  236  VAL A N   1 
ATOM   922  C CA  . VAL A 1 236 ? 114.784 112.813 120.080 1.00 259.83 ?  236  VAL A CA  1 
ATOM   923  C C   . VAL A 1 236 ? 113.855 112.430 118.938 1.00 259.83 ?  236  VAL A C   1 
ATOM   924  O O   . VAL A 1 236 ? 113.268 113.299 118.301 1.00 259.83 ?  236  VAL A O   1 
ATOM   925  C CB  . VAL A 1 236 ? 116.264 112.767 119.654 1.00 259.83 ?  236  VAL A CB  1 
ATOM   926  C CG1 . VAL A 1 236 ? 116.432 112.994 118.161 1.00 259.83 ?  236  VAL A CG1 1 
ATOM   927  C CG2 . VAL A 1 236 ? 117.068 113.783 120.445 1.00 259.83 ?  236  VAL A CG2 1 
ATOM   928  N N   . HIS A 1 237 ? 113.683 111.132 118.700 1.00 254.65 ?  237  HIS A N   1 
ATOM   929  C CA  . HIS A 1 237 ? 112.760 110.679 117.663 1.00 254.65 ?  237  HIS A CA  1 
ATOM   930  C C   . HIS A 1 237 ? 111.325 111.020 118.037 1.00 254.65 ?  237  HIS A C   1 
ATOM   931  O O   . HIS A 1 237 ? 110.591 111.556 117.219 1.00 254.65 ?  237  HIS A O   1 
ATOM   932  C CB  . HIS A 1 237 ? 112.910 109.174 117.425 1.00 254.65 ?  237  HIS A CB  1 
ATOM   933  C CG  . HIS A 1 237 ? 112.041 108.641 116.328 1.00 254.65 ?  237  HIS A CG  1 
ATOM   934  N ND1 . HIS A 1 237 ? 111.632 107.326 116.278 1.00 254.65 ?  237  HIS A ND1 1 
ATOM   935  C CD2 . HIS A 1 237 ? 111.508 109.240 115.237 1.00 254.65 ?  237  HIS A CD2 1 
ATOM   936  C CE1 . HIS A 1 237 ? 110.878 107.140 115.210 1.00 254.65 ?  237  HIS A CE1 1 
ATOM   937  N NE2 . HIS A 1 237 ? 110.787 108.286 114.561 1.00 254.65 ?  237  HIS A NE2 1 
ATOM   938  N N   . ILE A 1 238 ? 110.924 110.724 119.268 1.00 265.51 ?  238  ILE A N   1 
ATOM   939  C CA  . ILE A 1 238 ? 109.574 111.038 119.734 1.00 265.51 ?  238  ILE A CA  1 
ATOM   940  C C   . ILE A 1 238 ? 109.296 112.517 119.537 1.00 265.51 ?  238  ILE A C   1 
ATOM   941  O O   . ILE A 1 238 ? 108.228 112.896 119.058 1.00 265.51 ?  238  ILE A O   1 
ATOM   942  C CB  . ILE A 1 238 ? 109.405 110.656 121.222 1.00 265.51 ?  238  ILE A CB  1 
ATOM   943  C CG1 . ILE A 1 238 ? 109.134 109.159 121.364 1.00 265.51 ?  238  ILE A CG1 1 
ATOM   944  C CG2 . ILE A 1 238 ? 108.302 111.456 121.894 1.00 265.51 ?  238  ILE A CG2 1 
ATOM   945  C CD1 . ILE A 1 238 ? 109.570 108.591 122.697 1.00 265.51 ?  238  ILE A CD1 1 
ATOM   946  N N   . ALA A 1 239 ? 110.268 113.356 119.866 1.00 245.47 ?  239  ALA A N   1 
ATOM   947  C CA  . ALA A 1 239 ? 110.085 114.793 119.743 1.00 245.47 ?  239  ALA A CA  1 
ATOM   948  C C   . ALA A 1 239 ? 110.052 115.261 118.307 1.00 245.47 ?  239  ALA A C   1 
ATOM   949  O O   . ALA A 1 239 ? 109.350 116.208 117.986 1.00 245.47 ?  239  ALA A O   1 
ATOM   950  C CB  . ALA A 1 239 ? 111.168 115.520 120.500 1.00 245.47 ?  239  ALA A CB  1 
ATOM   951  N N   . SER A 1 240 ? 110.814 114.609 117.440 1.00 275.90 ?  240  SER A N   1 
ATOM   952  C CA  . SER A 1 240 ? 110.807 114.965 116.033 1.00 275.90 ?  240  SER A CA  1 
ATOM   953  C C   . SER A 1 240 ? 109.501 114.537 115.395 1.00 275.90 ?  240  SER A C   1 
ATOM   954  O O   . SER A 1 240 ? 109.007 115.211 114.498 1.00 275.90 ?  240  SER A O   1 
ATOM   955  C CB  . SER A 1 240 ? 111.992 114.333 115.316 1.00 275.90 ?  240  SER A CB  1 
ATOM   956  O OG  . SER A 1 240 ? 113.209 114.912 115.750 1.00 275.90 ?  240  SER A OG  1 
ATOM   957  N N   . ILE A 1 241 ? 108.930 113.426 115.848 1.00 272.13 ?  241  ILE A N   1 
ATOM   958  C CA  . ILE A 1 241 ? 107.629 113.017 115.339 1.00 272.13 ?  241  ILE A CA  1 
ATOM   959  C C   . ILE A 1 241 ? 106.645 114.081 115.760 1.00 272.13 ?  241  ILE A C   1 
ATOM   960  O O   . ILE A 1 241 ? 105.877 114.579 114.947 1.00 272.13 ?  241  ILE A O   1 
ATOM   961  C CB  . ILE A 1 241 ? 107.157 111.674 115.921 1.00 272.13 ?  241  ILE A CB  1 
ATOM   962  C CG1 . ILE A 1 241 ? 108.039 110.526 115.446 1.00 272.13 ?  241  ILE A CG1 1 
ATOM   963  C CG2 . ILE A 1 241 ? 105.720 111.396 115.518 1.00 272.13 ?  241  ILE A CG2 1 
ATOM   964  C CD1 . ILE A 1 241 ? 107.981 109.320 116.353 1.00 272.13 ?  241  ILE A CD1 1 
ATOM   965  N N   . CYS A 1 242 ? 106.686 114.455 117.031 1.00 298.43 ?  242  CYS A N   1 
ATOM   966  C CA  . CYS A 1 242 ? 105.774 115.465 117.538 1.00 298.43 ?  242  CYS A CA  1 
ATOM   967  C C   . CYS A 1 242 ? 105.961 116.795 116.835 1.00 298.43 ?  242  CYS A C   1 
ATOM   968  O O   . CYS A 1 242 ? 104.995 117.505 116.604 1.00 298.43 ?  242  CYS A O   1 
ATOM   969  C CB  . CYS A 1 242 ? 105.959 115.640 119.038 1.00 298.43 ?  242  CYS A CB  1 
ATOM   970  S SG  . CYS A 1 242 ? 104.451 115.455 120.010 1.00 298.43 ?  242  CYS A SG  1 
ATOM   971  N N   . ALA A 1 243 ? 107.197 117.137 116.491 1.00 278.91 ?  243  ALA A N   1 
ATOM   972  C CA  . ALA A 1 243 ? 107.458 118.376 115.773 1.00 278.91 ?  243  ALA A CA  1 
ATOM   973  C C   . ALA A 1 243 ? 106.806 118.327 114.413 1.00 278.91 ?  243  ALA A C   1 
ATOM   974  O O   . ALA A 1 243 ? 106.115 119.258 114.024 1.00 278.91 ?  243  ALA A O   1 
ATOM   975  C CB  . ALA A 1 243 ? 108.948 118.607 115.635 1.00 278.91 ?  243  ALA A CB  1 
ATOM   976  N N   . ALA A 1 244 ? 107.017 117.236 113.688 1.00 296.98 ?  244  ALA A N   1 
ATOM   977  C CA  . ALA A 1 244 ? 106.403 117.081 112.378 1.00 296.98 ?  244  ALA A CA  1 
ATOM   978  C C   . ALA A 1 244 ? 104.889 117.118 112.482 1.00 296.98 ?  244  ALA A C   1 
ATOM   979  O O   . ALA A 1 244 ? 104.226 117.774 111.684 1.00 296.98 ?  244  ALA A O   1 
ATOM   980  C CB  . ALA A 1 244 ? 106.853 115.783 111.739 1.00 296.98 ?  244  ALA A CB  1 
ATOM   981  N N   . VAL A 1 245 ? 104.337 116.418 113.466 1.00 291.00 ?  245  VAL A N   1 
ATOM   982  C CA  . VAL A 1 245 ? 102.893 116.392 113.645 1.00 291.00 ?  245  VAL A CA  1 
ATOM   983  C C   . VAL A 1 245 ? 102.376 117.785 113.961 1.00 291.00 ?  245  VAL A C   1 
ATOM   984  O O   . VAL A 1 245 ? 101.414 118.239 113.354 1.00 291.00 ?  245  VAL A O   1 
ATOM   985  C CB  . VAL A 1 245 ? 102.479 115.397 114.745 1.00 291.00 ?  245  VAL A CB  1 
ATOM   986  C CG1 . VAL A 1 245 ? 101.039 115.622 115.180 1.00 291.00 ?  245  VAL A CG1 1 
ATOM   987  C CG2 . VAL A 1 245 ? 102.663 113.969 114.256 1.00 291.00 ?  245  VAL A CG2 1 
ATOM   988  N N   . LEU A 1 246 ? 103.027 118.476 114.890 1.00 301.56 ?  246  LEU A N   1 
ATOM   989  C CA  . LEU A 1 246 ? 102.600 119.819 115.258 1.00 301.56 ?  246  LEU A CA  1 
ATOM   990  C C   . LEU A 1 246 ? 102.691 120.752 114.069 1.00 301.56 ?  246  LEU A C   1 
ATOM   991  O O   . LEU A 1 246 ? 101.833 121.605 113.888 1.00 301.56 ?  246  LEU A O   1 
ATOM   992  C CB  . LEU A 1 246 ? 103.434 120.364 116.414 1.00 301.56 ?  246  LEU A CB  1 
ATOM   993  C CG  . LEU A 1 246 ? 102.685 120.618 117.720 1.00 301.56 ?  246  LEU A CG  1 
ATOM   994  C CD1 . LEU A 1 246 ? 101.287 120.028 117.661 1.00 301.56 ?  246  LEU A CD1 1 
ATOM   995  C CD2 . LEU A 1 246 ? 103.458 120.031 118.887 1.00 301.56 ?  246  LEU A CD2 1 
ATOM   996  N N   . SER A 1 247 ? 103.724 120.591 113.252 1.00 308.97 ?  247  SER A N   1 
ATOM   997  C CA  . SER A 1 247 ? 103.874 121.423 112.068 1.00 308.97 ?  247  SER A CA  1 
ATOM   998  C C   . SER A 1 247 ? 102.703 121.215 111.124 1.00 308.97 ?  247  SER A C   1 
ATOM   999  O O   . SER A 1 247 ? 102.168 122.172 110.583 1.00 308.97 ?  247  SER A O   1 
ATOM   1000 C CB  . SER A 1 247 ? 105.191 121.123 111.358 1.00 308.97 ?  247  SER A CB  1 
ATOM   1001 O OG  . SER A 1 247 ? 104.968 120.636 110.047 1.00 308.97 ?  247  SER A OG  1 
ATOM   1002 N N   . LYS A 1 248 ? 102.292 119.968 110.934 1.00 305.64 ?  248  LYS A N   1 
ATOM   1003 C CA  . LYS A 1 248 ? 101.145 119.688 110.082 1.00 305.64 ?  248  LYS A CA  1 
ATOM   1004 C C   . LYS A 1 248 ? 99.878  120.238 110.709 1.00 305.64 ?  248  LYS A C   1 
ATOM   1005 O O   . LYS A 1 248 ? 99.095  120.912 110.047 1.00 305.64 ?  248  LYS A O   1 
ATOM   1006 C CB  . LYS A 1 248 ? 101.004 118.187 109.852 1.00 305.64 ?  248  LYS A CB  1 
ATOM   1007 C CG  . LYS A 1 248 ? 102.004 117.618 108.863 1.00 305.64 ?  248  LYS A CG  1 
ATOM   1008 C CD  . LYS A 1 248 ? 101.438 116.397 108.158 1.00 305.64 ?  248  LYS A CD  1 
ATOM   1009 C CE  . LYS A 1 248 ? 100.489 116.797 107.040 1.00 305.64 ?  248  LYS A CE  1 
ATOM   1010 N NZ  . LYS A 1 248 ? 99.084  116.394 107.326 1.00 305.64 1  248  LYS A NZ  1 
ATOM   1011 N N   . PHE A 1 249 ? 99.680  119.969 111.992 1.00 306.46 ?  249  PHE A N   1 
ATOM   1012 C CA  . PHE A 1 249 ? 98.496  120.454 112.687 1.00 306.46 ?  249  PHE A CA  1 
ATOM   1013 C C   . PHE A 1 249 ? 98.388  121.969 112.594 1.00 306.46 ?  249  PHE A C   1 
ATOM   1014 O O   . PHE A 1 249 ? 97.296  122.509 112.451 1.00 306.46 ?  249  PHE A O   1 
ATOM   1015 C CB  . PHE A 1 249 ? 98.517  119.987 114.148 1.00 306.46 ?  249  PHE A CB  1 
ATOM   1016 C CG  . PHE A 1 249 ? 97.838  120.927 115.107 1.00 306.46 ?  249  PHE A CG  1 
ATOM   1017 C CD1 . PHE A 1 249 ? 96.457  120.939 115.229 1.00 306.46 ?  249  PHE A CD1 1 
ATOM   1018 C CD2 . PHE A 1 249 ? 98.582  121.786 115.901 1.00 306.46 ?  249  PHE A CD2 1 
ATOM   1019 C CE1 . PHE A 1 249 ? 95.833  121.802 116.109 1.00 306.46 ?  249  PHE A CE1 1 
ATOM   1020 C CE2 . PHE A 1 249 ? 97.964  122.650 116.784 1.00 306.46 ?  249  PHE A CE2 1 
ATOM   1021 C CZ  . PHE A 1 249 ? 96.587  122.657 116.889 1.00 306.46 ?  249  PHE A CZ  1 
ATOM   1022 N N   . MET A 1 250 ? 99.515  122.662 112.670 1.00 308.01 ?  250  MET A N   1 
ATOM   1023 C CA  . MET A 1 250 ? 99.476  124.115 112.658 1.00 308.01 ?  250  MET A CA  1 
ATOM   1024 C C   . MET A 1 250 ? 99.460  124.683 111.254 1.00 308.01 ?  250  MET A C   1 
ATOM   1025 O O   . MET A 1 250 ? 98.496  125.333 110.859 1.00 308.01 ?  250  MET A O   1 
ATOM   1026 C CB  . MET A 1 250 ? 100.657 124.686 113.437 1.00 308.01 ?  250  MET A CB  1 
ATOM   1027 C CG  . MET A 1 250 ? 100.272 125.781 114.411 1.00 308.01 ?  250  MET A CG  1 
ATOM   1028 S SD  . MET A 1 250 ? 101.467 125.935 115.745 1.00 308.01 ?  250  MET A SD  1 
ATOM   1029 C CE  . MET A 1 250 ? 101.522 124.249 116.340 1.00 308.01 ?  250  MET A CE  1 
ATOM   1030 N N   . SER A 1 251 ? 100.521 124.446 110.497 1.00 303.41 ?  251  SER A N   1 
ATOM   1031 C CA  . SER A 1 251 ? 100.619 125.023 109.160 1.00 303.41 ?  251  SER A CA  1 
ATOM   1032 C C   . SER A 1 251 ? 99.578  124.505 108.186 1.00 303.41 ?  251  SER A C   1 
ATOM   1033 O O   . SER A 1 251 ? 98.775  125.280 107.669 1.00 303.41 ?  251  SER A O   1 
ATOM   1034 C CB  . SER A 1 251 ? 102.023 124.816 108.584 1.00 303.41 ?  251  SER A CB  1 
ATOM   1035 O OG  . SER A 1 251 ? 102.013 124.905 107.171 1.00 303.41 ?  251  SER A OG  1 
ATOM   1036 N N   . VAL A 1 252 ? 99.578  123.205 107.925 1.00 294.29 ?  252  VAL A N   1 
ATOM   1037 C CA  . VAL A 1 252 ? 98.659  122.673 106.920 1.00 294.29 ?  252  VAL A CA  1 
ATOM   1038 C C   . VAL A 1 252 ? 97.198  122.658 107.376 1.00 294.29 ?  252  VAL A C   1 
ATOM   1039 O O   . VAL A 1 252 ? 96.289  122.606 106.545 1.00 294.29 ?  252  VAL A O   1 
ATOM   1040 C CB  . VAL A 1 252 ? 99.135  121.308 106.362 1.00 294.29 ?  252  VAL A CB  1 
ATOM   1041 C CG1 . VAL A 1 252 ? 100.632 121.143 106.571 1.00 294.29 ?  252  VAL A CG1 1 
ATOM   1042 C CG2 . VAL A 1 252 ? 98.369  120.145 106.967 1.00 294.29 ?  252  VAL A CG2 1 
ATOM   1043 N N   . PHE A 1 253 ? 96.962  122.735 108.683 1.00 291.46 ?  253  PHE A N   1 
ATOM   1044 C CA  . PHE A 1 253 ? 95.590  122.797 109.178 1.00 291.46 ?  253  PHE A CA  1 
ATOM   1045 C C   . PHE A 1 253 ? 95.338  124.117 109.896 1.00 291.46 ?  253  PHE A C   1 
ATOM   1046 O O   . PHE A 1 253 ? 94.964  124.135 111.067 1.00 291.46 ?  253  PHE A O   1 
ATOM   1047 C CB  . PHE A 1 253 ? 95.285  121.624 110.111 1.00 291.46 ?  253  PHE A CB  1 
ATOM   1048 C CG  . PHE A 1 253 ? 95.402  120.277 109.457 1.00 291.46 ?  253  PHE A CG  1 
ATOM   1049 C CD1 . PHE A 1 253 ? 94.728  120.002 108.279 1.00 291.46 ?  253  PHE A CD1 1 
ATOM   1050 C CD2 . PHE A 1 253 ? 96.179  119.282 110.025 1.00 291.46 ?  253  PHE A CD2 1 
ATOM   1051 C CE1 . PHE A 1 253 ? 94.835  118.763 107.676 1.00 291.46 ?  253  PHE A CE1 1 
ATOM   1052 C CE2 . PHE A 1 253 ? 96.291  118.042 109.429 1.00 291.46 ?  253  PHE A CE2 1 
ATOM   1053 C CZ  . PHE A 1 253 ? 95.616  117.781 108.252 1.00 291.46 ?  253  PHE A CZ  1 
ATOM   1054 N N   . TYR A 1 262 ? 112.417 125.715 107.251 1.00 316.42 ?  262  TYR A N   1 
ATOM   1055 C CA  . TYR A 1 262 ? 111.990 124.573 106.453 1.00 316.42 ?  262  TYR A CA  1 
ATOM   1056 C C   . TYR A 1 262 ? 111.773 123.349 107.329 1.00 316.42 ?  262  TYR A C   1 
ATOM   1057 O O   . TYR A 1 262 ? 111.701 123.465 108.549 1.00 316.42 ?  262  TYR A O   1 
ATOM   1058 C CB  . TYR A 1 262 ? 113.005 124.267 105.346 1.00 316.42 ?  262  TYR A CB  1 
ATOM   1059 C CG  . TYR A 1 262 ? 114.400 124.793 105.608 1.00 316.42 ?  262  TYR A CG  1 
ATOM   1060 C CD1 . TYR A 1 262 ? 115.307 124.061 106.359 1.00 316.42 ?  262  TYR A CD1 1 
ATOM   1061 C CD2 . TYR A 1 262 ? 114.813 126.015 105.092 1.00 316.42 ?  262  TYR A CD2 1 
ATOM   1062 C CE1 . TYR A 1 262 ? 116.583 124.533 106.597 1.00 316.42 ?  262  TYR A CE1 1 
ATOM   1063 C CE2 . TYR A 1 262 ? 116.086 126.496 105.329 1.00 316.42 ?  262  TYR A CE2 1 
ATOM   1064 C CZ  . TYR A 1 262 ? 116.966 125.750 106.082 1.00 316.42 ?  262  TYR A CZ  1 
ATOM   1065 O OH  . TYR A 1 262 ? 118.237 126.222 106.319 1.00 316.42 ?  262  TYR A OH  1 
ATOM   1066 N N   . TYR A 1 263 ? 111.671 122.178 106.712 1.00 309.96 ?  263  TYR A N   1 
ATOM   1067 C CA  . TYR A 1 263 ? 111.450 120.951 107.467 1.00 309.96 ?  263  TYR A CA  1 
ATOM   1068 C C   . TYR A 1 263 ? 112.597 120.686 108.425 1.00 309.96 ?  263  TYR A C   1 
ATOM   1069 O O   . TYR A 1 263 ? 112.383 120.215 109.538 1.00 309.96 ?  263  TYR A O   1 
ATOM   1070 C CB  . TYR A 1 263 ? 111.282 119.769 106.515 1.00 309.96 ?  263  TYR A CB  1 
ATOM   1071 C CG  . TYR A 1 263 ? 110.535 118.594 107.102 1.00 309.96 ?  263  TYR A CG  1 
ATOM   1072 C CD1 . TYR A 1 263 ? 109.543 118.779 108.056 1.00 309.96 ?  263  TYR A CD1 1 
ATOM   1073 C CD2 . TYR A 1 263 ? 110.820 117.298 106.695 1.00 309.96 ?  263  TYR A CD2 1 
ATOM   1074 C CE1 . TYR A 1 263 ? 108.859 117.704 108.592 1.00 309.96 ?  263  TYR A CE1 1 
ATOM   1075 C CE2 . TYR A 1 263 ? 110.140 116.218 107.224 1.00 309.96 ?  263  TYR A CE2 1 
ATOM   1076 C CZ  . TYR A 1 263 ? 109.162 116.426 108.171 1.00 309.96 ?  263  TYR A CZ  1 
ATOM   1077 O OH  . TYR A 1 263 ? 108.487 115.350 108.695 1.00 309.96 ?  263  TYR A OH  1 
ATOM   1078 N N   . SER A 1 264 ? 113.815 120.996 108.001 1.00 293.58 ?  264  SER A N   1 
ATOM   1079 C CA  . SER A 1 264 ? 114.977 120.767 108.847 1.00 293.58 ?  264  SER A CA  1 
ATOM   1080 C C   . SER A 1 264 ? 114.931 121.638 110.086 1.00 293.58 ?  264  SER A C   1 
ATOM   1081 O O   . SER A 1 264 ? 115.355 121.214 111.151 1.00 293.58 ?  264  SER A O   1 
ATOM   1082 C CB  . SER A 1 264 ? 116.272 121.019 108.077 1.00 293.58 ?  264  SER A CB  1 
ATOM   1083 O OG  . SER A 1 264 ? 117.179 121.787 108.847 1.00 293.58 ?  264  SER A OG  1 
ATOM   1084 N N   . ASP A 1 265 ? 114.412 122.852 109.954 1.00 302.56 ?  265  ASP A N   1 
ATOM   1085 C CA  . ASP A 1 265 ? 114.292 123.740 111.101 1.00 302.56 ?  265  ASP A CA  1 
ATOM   1086 C C   . ASP A 1 265 ? 113.318 123.165 112.108 1.00 302.56 ?  265  ASP A C   1 
ATOM   1087 O O   . ASP A 1 265 ? 113.606 123.127 113.302 1.00 302.56 ?  265  ASP A O   1 
ATOM   1088 C CB  . ASP A 1 265 ? 113.833 125.122 110.651 1.00 302.56 ?  265  ASP A CB  1 
ATOM   1089 C CG  . ASP A 1 265 ? 114.858 125.817 109.783 1.00 302.56 ?  265  ASP A CG  1 
ATOM   1090 O OD1 . ASP A 1 265 ? 116.008 125.336 109.729 1.00 302.56 ?  265  ASP A OD1 1 
ATOM   1091 O OD2 . ASP A 1 265 ? 114.518 126.840 109.155 1.00 302.56 -1 265  ASP A OD2 1 
ATOM   1092 N N   . ILE A 1 266 ? 112.167 122.710 111.634 1.00 288.36 ?  266  ILE A N   1 
ATOM   1093 C CA  . ILE A 1 266 ? 111.182 122.097 112.513 1.00 288.36 ?  266  ILE A CA  1 
ATOM   1094 C C   . ILE A 1 266 ? 111.794 120.911 113.242 1.00 288.36 ?  266  ILE A C   1 
ATOM   1095 O O   . ILE A 1 266 ? 111.692 120.805 114.465 1.00 288.36 ?  266  ILE A O   1 
ATOM   1096 C CB  . ILE A 1 266 ? 109.949 121.651 111.700 1.00 288.36 ?  266  ILE A CB  1 
ATOM   1097 C CG1 . ILE A 1 266 ? 109.071 122.857 111.371 1.00 288.36 ?  266  ILE A CG1 1 
ATOM   1098 C CG2 . ILE A 1 266 ? 109.143 120.591 112.431 1.00 288.36 ?  266  ILE A CG2 1 
ATOM   1099 C CD1 . ILE A 1 266 ? 108.529 122.846 109.960 1.00 288.36 ?  266  ILE A CD1 1 
ATOM   1100 N N   . LEU A 1 267 ? 112.413 120.006 112.492 1.00 268.67 ?  267  LEU A N   1 
ATOM   1101 C CA  . LEU A 1 267 ? 112.951 118.786 113.088 1.00 268.67 ?  267  LEU A CA  1 
ATOM   1102 C C   . LEU A 1 267 ? 114.087 119.032 114.050 1.00 268.67 ?  267  LEU A C   1 
ATOM   1103 O O   . LEU A 1 267 ? 114.243 118.302 115.020 1.00 268.67 ?  267  LEU A O   1 
ATOM   1104 C CB  . LEU A 1 267 ? 113.416 117.829 111.994 1.00 268.67 ?  267  LEU A CB  1 
ATOM   1105 C CG  . LEU A 1 267 ? 112.473 116.708 111.563 1.00 268.67 ?  267  LEU A CG  1 
ATOM   1106 C CD1 . LEU A 1 267 ? 111.038 116.982 111.987 1.00 268.67 ?  267  LEU A CD1 1 
ATOM   1107 C CD2 . LEU A 1 267 ? 112.566 116.530 110.059 1.00 268.67 ?  267  LEU A CD2 1 
ATOM   1108 N N   . THR A 1 268 ? 114.888 120.054 113.788 1.00 265.95 ?  268  THR A N   1 
ATOM   1109 C CA  . THR A 1 268 ? 116.041 120.306 114.636 1.00 265.95 ?  268  THR A CA  1 
ATOM   1110 C C   . THR A 1 268 ? 115.623 120.936 115.953 1.00 265.95 ?  268  THR A C   1 
ATOM   1111 O O   . THR A 1 268 ? 116.338 120.821 116.948 1.00 265.95 ?  268  THR A O   1 
ATOM   1112 C CB  . THR A 1 268 ? 117.123 121.122 113.907 1.00 30.00  ?  268  THR A CB  1 
ATOM   1113 O OG1 . THR A 1 268 ? 118.418 120.704 114.356 1.00 30.00  ?  268  THR A OG1 1 
ATOM   1114 C CG2 . THR A 1 268 ? 116.955 122.590 114.163 1.00 30.00  ?  268  THR A CG2 1 
ATOM   1115 N N   . VAL A 1 269 ? 114.466 121.590 115.981 1.00 271.98 ?  269  VAL A N   1 
ATOM   1116 C CA  . VAL A 1 269 ? 113.962 122.124 117.238 1.00 271.98 ?  269  VAL A CA  1 
ATOM   1117 C C   . VAL A 1 269 ? 113.408 120.921 117.964 1.00 271.98 ?  269  VAL A C   1 
ATOM   1118 O O   . VAL A 1 269 ? 113.596 120.786 119.167 1.00 271.98 ?  269  VAL A O   1 
ATOM   1119 C CB  . VAL A 1 269 ? 112.875 123.184 117.012 1.00 271.98 ?  269  VAL A CB  1 
ATOM   1120 C CG1 . VAL A 1 269 ? 112.165 123.514 118.313 1.00 271.98 ?  269  VAL A CG1 1 
ATOM   1121 C CG2 . VAL A 1 269 ? 113.495 124.436 116.417 1.00 271.98 ?  269  VAL A CG2 1 
ATOM   1122 N N   . GLY A 1 270 ? 112.739 120.033 117.237 1.00 274.45 ?  270  GLY A N   1 
ATOM   1123 C CA  . GLY A 1 270 ? 112.259 118.801 117.834 1.00 274.45 ?  270  GLY A CA  1 
ATOM   1124 C C   . GLY A 1 270 ? 113.366 118.095 118.580 1.00 274.45 ?  270  GLY A C   1 
ATOM   1125 O O   . GLY A 1 270 ? 113.225 117.786 119.755 1.00 274.45 ?  270  GLY A O   1 
ATOM   1126 N N   . CYS A 1 271 ? 114.484 117.855 117.909 1.00 276.29 ?  271  CYS A N   1 
ATOM   1127 C CA  . CYS A 1 271 ? 115.617 117.211 118.553 1.00 276.29 ?  271  CYS A CA  1 
ATOM   1128 C C   . CYS A 1 271 ? 116.003 117.916 119.842 1.00 276.29 ?  271  CYS A C   1 
ATOM   1129 O O   . CYS A 1 271 ? 116.180 117.268 120.866 1.00 276.29 ?  271  CYS A O   1 
ATOM   1130 C CB  . CYS A 1 271 ? 116.810 117.169 117.603 1.00 276.29 ?  271  CYS A CB  1 
ATOM   1131 S SG  . CYS A 1 271 ? 116.542 116.209 116.097 1.00 276.29 ?  271  CYS A SG  1 
ATOM   1132 N N   . ALA A 1 272 ? 116.124 119.239 119.801 1.00 296.18 ?  272  ALA A N   1 
ATOM   1133 C CA  . ALA A 1 272 ? 116.511 120.010 120.983 1.00 296.18 ?  272  ALA A CA  1 
ATOM   1134 C C   . ALA A 1 272 ? 115.596 119.805 122.181 1.00 296.18 ?  272  ALA A C   1 
ATOM   1135 O O   . ALA A 1 272 ? 116.067 119.572 123.291 1.00 296.18 ?  272  ALA A O   1 
ATOM   1136 C CB  . ALA A 1 272 ? 116.594 121.483 120.640 1.00 296.18 ?  272  ALA A CB  1 
ATOM   1137 N N   . VAL A 1 273 ? 114.288 119.892 121.965 1.00 306.83 ?  273  VAL A N   1 
ATOM   1138 C CA  . VAL A 1 273 ? 113.342 119.731 123.062 1.00 306.83 ?  273  VAL A CA  1 
ATOM   1139 C C   . VAL A 1 273 ? 113.240 118.285 123.502 1.00 306.83 ?  273  VAL A C   1 
ATOM   1140 O O   . VAL A 1 273 ? 112.785 118.008 124.605 1.00 306.83 ?  273  VAL A O   1 
ATOM   1141 C CB  . VAL A 1 273 ? 111.950 120.298 122.720 1.00 306.83 ?  273  VAL A CB  1 
ATOM   1142 C CG1 . VAL A 1 273 ? 112.101 121.614 121.993 1.00 306.83 ?  273  VAL A CG1 1 
ATOM   1143 C CG2 . VAL A 1 273 ? 111.139 119.325 121.883 1.00 306.83 ?  273  VAL A CG2 1 
ATOM   1144 N N   . GLY A 1 274 ? 113.674 117.360 122.655 1.00 284.31 ?  274  GLY A N   1 
ATOM   1145 C CA  . GLY A 1 274 ? 113.663 115.962 123.024 1.00 284.31 ?  274  GLY A CA  1 
ATOM   1146 C C   . GLY A 1 274 ? 114.671 115.717 124.113 1.00 284.31 ?  274  GLY A C   1 
ATOM   1147 O O   . GLY A 1 274 ? 114.343 115.169 125.158 1.00 284.31 ?  274  GLY A O   1 
ATOM   1148 N N   . VAL A 1 275 ? 115.907 116.139 123.881 1.00 263.92 ?  275  VAL A N   1 
ATOM   1149 C CA  . VAL A 1 275 ? 116.952 115.918 124.868 1.00 263.92 ?  275  VAL A CA  1 
ATOM   1150 C C   . VAL A 1 275 ? 116.796 116.871 126.038 1.00 263.92 ?  275  VAL A C   1 
ATOM   1151 O O   . VAL A 1 275 ? 117.226 116.572 127.146 1.00 263.92 ?  275  VAL A O   1 
ATOM   1152 C CB  . VAL A 1 275 ? 118.354 116.039 124.257 1.00 263.92 ?  275  VAL A CB  1 
ATOM   1153 C CG1 . VAL A 1 275 ? 118.801 114.695 123.721 1.00 263.92 ?  275  VAL A CG1 1 
ATOM   1154 C CG2 . VAL A 1 275 ? 118.354 117.051 123.136 1.00 263.92 ?  275  VAL A CG2 1 
ATOM   1155 N N   . GLY A 1 276 ? 116.167 118.013 125.803 1.00 285.28 ?  276  GLY A N   1 
ATOM   1156 C CA  . GLY A 1 276 ? 115.931 118.955 126.877 1.00 285.28 ?  276  GLY A CA  1 
ATOM   1157 C C   . GLY A 1 276 ? 114.957 118.389 127.883 1.00 285.28 ?  276  GLY A C   1 
ATOM   1158 O O   . GLY A 1 276 ? 115.121 118.583 129.084 1.00 285.28 ?  276  GLY A O   1 
ATOM   1159 N N   . CYS A 1 277 ? 113.942 117.682 127.400 1.00 314.53 ?  277  CYS A N   1 
ATOM   1160 C CA  . CYS A 1 277 ? 112.949 117.093 128.289 1.00 314.53 ?  277  CYS A CA  1 
ATOM   1161 C C   . CYS A 1 277 ? 113.400 115.725 128.782 1.00 314.53 ?  277  CYS A C   1 
ATOM   1162 O O   . CYS A 1 277 ? 112.824 115.181 129.721 1.00 314.53 ?  277  CYS A O   1 
ATOM   1163 C CB  . CYS A 1 277 ? 111.585 117.019 127.597 1.00 314.53 ?  277  CYS A CB  1 
ATOM   1164 S SG  . CYS A 1 277 ? 111.357 115.603 126.505 1.00 314.53 ?  277  CYS A SG  1 
ATOM   1165 N N   . CYS A 1 278 ? 114.437 115.173 128.164 1.00 274.97 ?  278  CYS A N   1 
ATOM   1166 C CA  . CYS A 1 278 ? 114.973 113.891 128.604 1.00 274.97 ?  278  CYS A CA  1 
ATOM   1167 C C   . CYS A 1 278 ? 115.863 114.080 129.814 1.00 274.97 ?  278  CYS A C   1 
ATOM   1168 O O   . CYS A 1 278 ? 115.662 113.442 130.844 1.00 274.97 ?  278  CYS A O   1 
ATOM   1169 C CB  . CYS A 1 278 ? 115.779 113.238 127.485 1.00 274.97 ?  278  CYS A CB  1 
ATOM   1170 S SG  . CYS A 1 278 ? 116.676 111.760 127.988 1.00 274.97 ?  278  CYS A SG  1 
ATOM   1171 N N   . PHE A 1 279 ? 116.848 114.966 129.697 1.00 227.42 ?  279  PHE A N   1 
ATOM   1172 C CA  . PHE A 1 279 ? 117.778 115.196 130.794 1.00 227.42 ?  279  PHE A CA  1 
ATOM   1173 C C   . PHE A 1 279 ? 117.224 116.184 131.798 1.00 227.42 ?  279  PHE A C   1 
ATOM   1174 O O   . PHE A 1 279 ? 117.838 116.410 132.836 1.00 227.42 ?  279  PHE A O   1 
ATOM   1175 C CB  . PHE A 1 279 ? 119.106 115.756 130.286 1.00 227.42 ?  279  PHE A CB  1 
ATOM   1176 C CG  . PHE A 1 279 ? 119.653 115.062 129.077 1.00 227.42 ?  279  PHE A CG  1 
ATOM   1177 C CD1 . PHE A 1 279 ? 119.651 113.684 128.982 1.00 227.42 ?  279  PHE A CD1 1 
ATOM   1178 C CD2 . PHE A 1 279 ? 120.203 115.799 128.044 1.00 227.42 ?  279  PHE A CD2 1 
ATOM   1179 C CE1 . PHE A 1 279 ? 120.159 113.056 127.866 1.00 227.42 ?  279  PHE A CE1 1 
ATOM   1180 C CE2 . PHE A 1 279 ? 120.720 115.177 126.928 1.00 227.42 ?  279  PHE A CE2 1 
ATOM   1181 C CZ  . PHE A 1 279 ? 120.700 113.803 126.839 1.00 227.42 ?  279  PHE A CZ  1 
ATOM   1182 N N   . GLY A 1 280 ? 116.081 116.794 131.500 1.00 219.72 ?  280  GLY A N   1 
ATOM   1183 C CA  . GLY A 1 280 ? 115.547 117.817 132.381 1.00 219.72 ?  280  GLY A CA  1 
ATOM   1184 C C   . GLY A 1 280 ? 116.567 118.925 132.411 1.00 219.72 ?  280  GLY A C   1 
ATOM   1185 O O   . GLY A 1 280 ? 116.774 119.559 133.445 1.00 219.72 ?  280  GLY A O   1 
ATOM   1186 N N   . THR A 1 281 ? 117.218 119.161 131.280 1.00 234.03 ?  281  THR A N   1 
ATOM   1187 C CA  . THR A 1 281 ? 118.263 120.166 131.210 1.00 234.03 ?  281  THR A CA  1 
ATOM   1188 C C   . THR A 1 281 ? 118.024 120.956 129.941 1.00 234.03 ?  281  THR A C   1 
ATOM   1189 O O   . THR A 1 281 ? 118.304 120.472 128.846 1.00 234.03 ?  281  THR A O   1 
ATOM   1190 C CB  . THR A 1 281 ? 119.648 119.493 131.158 1.00 234.03 ?  281  THR A CB  1 
ATOM   1191 O OG1 . THR A 1 281 ? 119.902 118.818 132.397 1.00 234.03 ?  281  THR A OG1 1 
ATOM   1192 C CG2 . THR A 1 281 ? 120.734 120.506 130.926 1.00 234.03 ?  281  THR A CG2 1 
ATOM   1193 N N   . PRO A 1 282 ? 117.473 122.168 130.075 1.00 231.49 ?  282  PRO A N   1 
ATOM   1194 C CA  . PRO A 1 282 ? 117.150 122.970 128.891 1.00 231.49 ?  282  PRO A CA  1 
ATOM   1195 C C   . PRO A 1 282 ? 118.371 123.312 128.053 1.00 231.49 ?  282  PRO A C   1 
ATOM   1196 O O   . PRO A 1 282 ? 118.495 122.801 126.943 1.00 231.49 ?  282  PRO A O   1 
ATOM   1197 C CB  . PRO A 1 282 ? 116.556 124.248 129.484 1.00 231.49 ?  282  PRO A CB  1 
ATOM   1198 C CG  . PRO A 1 282 ? 116.105 123.871 130.853 1.00 231.49 ?  282  PRO A CG  1 
ATOM   1199 C CD  . PRO A 1 282 ? 117.073 122.832 131.325 1.00 231.49 ?  282  PRO A CD  1 
ATOM   1200 N N   . LEU A 1 283 ? 119.260 124.152 128.568 1.00 229.79 ?  283  LEU A N   1 
ATOM   1201 C CA  . LEU A 1 283 ? 120.418 124.592 127.792 1.00 229.79 ?  283  LEU A CA  1 
ATOM   1202 C C   . LEU A 1 283 ? 121.280 123.442 127.306 1.00 229.79 ?  283  LEU A C   1 
ATOM   1203 O O   . LEU A 1 283 ? 121.573 123.343 126.115 1.00 229.79 ?  283  LEU A O   1 
ATOM   1204 C CB  . LEU A 1 283 ? 121.264 125.574 128.605 1.00 229.79 ?  283  LEU A CB  1 
ATOM   1205 C CG  . LEU A 1 283 ? 122.140 126.552 127.821 1.00 229.79 ?  283  LEU A CG  1 
ATOM   1206 C CD1 . LEU A 1 283 ? 121.908 127.975 128.301 1.00 229.79 ?  283  LEU A CD1 1 
ATOM   1207 C CD2 . LEU A 1 283 ? 123.608 126.181 127.956 1.00 229.79 ?  283  LEU A CD2 1 
ATOM   1208 N N   . GLY A 1 284 ? 121.691 122.574 128.222 1.00 243.51 ?  284  GLY A N   1 
ATOM   1209 C CA  . GLY A 1 284 ? 122.526 121.447 127.852 1.00 243.51 ?  284  GLY A CA  1 
ATOM   1210 C C   . GLY A 1 284 ? 121.907 120.598 126.769 1.00 243.51 ?  284  GLY A C   1 
ATOM   1211 O O   . GLY A 1 284 ? 122.598 120.179 125.851 1.00 243.51 ?  284  GLY A O   1 
ATOM   1212 N N   . GLY A 1 285 ? 120.608 120.344 126.867 1.00 256.46 ?  285  GLY A N   1 
ATOM   1213 C CA  . GLY A 1 285 ? 119.920 119.553 125.866 1.00 256.46 ?  285  GLY A CA  1 
ATOM   1214 C C   . GLY A 1 285 ? 119.987 120.158 124.483 1.00 256.46 ?  285  GLY A C   1 
ATOM   1215 O O   . GLY A 1 285 ? 120.329 119.476 123.527 1.00 256.46 ?  285  GLY A O   1 
ATOM   1216 N N   . VAL A 1 286 ? 119.666 121.441 124.366 1.00 248.56 ?  286  VAL A N   1 
ATOM   1217 C CA  . VAL A 1 286 ? 119.740 122.114 123.074 1.00 248.56 ?  286  VAL A CA  1 
ATOM   1218 C C   . VAL A 1 286 ? 121.126 121.957 122.479 1.00 248.56 ?  286  VAL A C   1 
ATOM   1219 O O   . VAL A 1 286 ? 121.269 121.542 121.329 1.00 248.56 ?  286  VAL A O   1 
ATOM   1220 C CB  . VAL A 1 286 ? 119.397 123.609 123.190 1.00 248.56 ?  286  VAL A CB  1 
ATOM   1221 C CG1 . VAL A 1 286 ? 119.380 124.263 121.818 1.00 248.56 ?  286  VAL A CG1 1 
ATOM   1222 C CG2 . VAL A 1 286 ? 118.052 123.784 123.869 1.00 248.56 ?  286  VAL A CG2 1 
ATOM   1223 N N   . LEU A 1 287 ? 122.152 122.263 123.266 1.00 238.93 ?  287  LEU A N   1 
ATOM   1224 C CA  . LEU A 1 287 ? 123.524 122.154 122.784 1.00 238.93 ?  287  LEU A CA  1 
ATOM   1225 C C   . LEU A 1 287 ? 123.865 120.729 122.385 1.00 238.93 ?  287  LEU A C   1 
ATOM   1226 O O   . LEU A 1 287 ? 124.507 120.508 121.360 1.00 238.93 ?  287  LEU A O   1 
ATOM   1227 C CB  . LEU A 1 287 ? 124.497 122.661 123.842 1.00 238.93 ?  287  LEU A CB  1 
ATOM   1228 C CG  . LEU A 1 287 ? 125.069 124.056 123.595 1.00 238.93 ?  287  LEU A CG  1 
ATOM   1229 C CD1 . LEU A 1 287 ? 125.226 124.308 122.104 1.00 238.93 ?  287  LEU A CD1 1 
ATOM   1230 C CD2 . LEU A 1 287 ? 124.184 125.114 124.230 1.00 238.93 ?  287  LEU A CD2 1 
ATOM   1231 N N   . PHE A 1 288 ? 123.435 119.761 123.183 1.00 237.90 ?  288  PHE A N   1 
ATOM   1232 C CA  . PHE A 1 288 ? 123.678 118.362 122.862 1.00 237.90 ?  288  PHE A CA  1 
ATOM   1233 C C   . PHE A 1 288 ? 123.112 118.026 121.503 1.00 237.90 ?  288  PHE A C   1 
ATOM   1234 O O   . PHE A 1 288 ? 123.822 117.501 120.657 1.00 237.90 ?  288  PHE A O   1 
ATOM   1235 C CB  . PHE A 1 288 ? 123.062 117.452 123.919 1.00 237.90 ?  288  PHE A CB  1 
ATOM   1236 C CG  . PHE A 1 288 ? 123.437 116.009 123.768 1.00 237.90 ?  288  PHE A CG  1 
ATOM   1237 C CD1 . PHE A 1 288 ? 124.692 115.564 124.137 1.00 237.90 ?  288  PHE A CD1 1 
ATOM   1238 C CD2 . PHE A 1 288 ? 122.531 115.096 123.260 1.00 237.90 ?  288  PHE A CD2 1 
ATOM   1239 C CE1 . PHE A 1 288 ? 125.038 114.236 124.001 1.00 237.90 ?  288  PHE A CE1 1 
ATOM   1240 C CE2 . PHE A 1 288 ? 122.872 113.768 123.119 1.00 237.90 ?  288  PHE A CE2 1 
ATOM   1241 C CZ  . PHE A 1 288 ? 124.128 113.336 123.490 1.00 237.90 ?  288  PHE A CZ  1 
ATOM   1242 N N   . SER A 1 289 ? 121.839 118.331 121.288 1.00 247.17 ?  289  SER A N   1 
ATOM   1243 C CA  . SER A 1 289 ? 121.196 118.033 120.014 1.00 247.17 ?  289  SER A CA  1 
ATOM   1244 C C   . SER A 1 289 ? 121.949 118.639 118.847 1.00 247.17 ?  289  SER A C   1 
ATOM   1245 O O   . SER A 1 289 ? 122.197 117.968 117.854 1.00 247.17 ?  289  SER A O   1 
ATOM   1246 C CB  . SER A 1 289 ? 119.761 118.537 120.011 1.00 247.17 ?  289  SER A CB  1 
ATOM   1247 O OG  . SER A 1 289 ? 119.494 119.319 118.861 1.00 247.17 ?  289  SER A OG  1 
ATOM   1248 N N   . ILE A 1 290 ? 122.316 119.908 118.963 1.00 266.47 ?  290  ILE A N   1 
ATOM   1249 C CA  . ILE A 1 290 ? 123.056 120.571 117.901 1.00 266.47 ?  290  ILE A CA  1 
ATOM   1250 C C   . ILE A 1 290 ? 124.275 119.745 117.522 1.00 266.47 ?  290  ILE A C   1 
ATOM   1251 O O   . ILE A 1 290 ? 124.526 119.504 116.342 1.00 266.47 ?  290  ILE A O   1 
ATOM   1252 C CB  . ILE A 1 290 ? 123.478 121.987 118.339 1.00 266.47 ?  290  ILE A CB  1 
ATOM   1253 C CG1 . ILE A 1 290 ? 122.299 122.950 118.224 1.00 266.47 ?  290  ILE A CG1 1 
ATOM   1254 C CG2 . ILE A 1 290 ? 124.661 122.494 117.528 1.00 266.47 ?  290  ILE A CG2 1 
ATOM   1255 C CD1 . ILE A 1 290 ? 122.418 124.152 119.129 1.00 266.47 ?  290  ILE A CD1 1 
ATOM   1256 N N   . GLU A 1 291 ? 125.017 119.276 118.518 1.00 258.40 ?  291  GLU A N   1 
ATOM   1257 C CA  . GLU A 1 291 ? 126.228 118.511 118.252 1.00 258.40 ?  291  GLU A CA  1 
ATOM   1258 C C   . GLU A 1 291 ? 125.991 117.120 117.676 1.00 258.40 ?  291  GLU A C   1 
ATOM   1259 O O   . GLU A 1 291 ? 126.737 116.684 116.803 1.00 258.40 ?  291  GLU A O   1 
ATOM   1260 C CB  . GLU A 1 291 ? 127.068 118.417 119.521 1.00 258.40 ?  291  GLU A CB  1 
ATOM   1261 C CG  . GLU A 1 291 ? 128.022 119.581 119.705 1.00 258.40 ?  291  GLU A CG  1 
ATOM   1262 C CD  . GLU A 1 291 ? 128.248 119.918 121.161 1.00 258.40 ?  291  GLU A CD  1 
ATOM   1263 O OE1 . GLU A 1 291 ? 127.750 120.968 121.615 1.00 258.40 ?  291  GLU A OE1 1 
ATOM   1264 O OE2 . GLU A 1 291 ? 128.924 119.130 121.851 1.00 258.40 -1 291  GLU A OE2 1 
ATOM   1265 N N   . VAL A 1 292 ? 124.967 116.417 118.150 1.00 252.65 ?  292  VAL A N   1 
ATOM   1266 C CA  . VAL A 1 292 ? 124.744 115.047 117.691 1.00 252.65 ?  292  VAL A CA  1 
ATOM   1267 C C   . VAL A 1 292 ? 123.892 114.912 116.442 1.00 252.65 ?  292  VAL A C   1 
ATOM   1268 O O   . VAL A 1 292 ? 123.865 113.843 115.846 1.00 252.65 ?  292  VAL A O   1 
ATOM   1269 C CB  . VAL A 1 292 ? 124.110 114.149 118.772 1.00 252.65 ?  292  VAL A CB  1 
ATOM   1270 C CG1 . VAL A 1 292 ? 125.118 113.779 119.837 1.00 252.65 ?  292  VAL A CG1 1 
ATOM   1271 C CG2 . VAL A 1 292 ? 122.873 114.786 119.369 1.00 252.65 ?  292  VAL A CG2 1 
ATOM   1272 N N   . THR A 1 293 ? 123.178 115.960 116.046 1.00 257.68 ?  293  THR A N   1 
ATOM   1273 C CA  . THR A 1 293 ? 122.273 115.831 114.906 1.00 257.68 ?  293  THR A CA  1 
ATOM   1274 C C   . THR A 1 293 ? 122.601 116.754 113.751 1.00 257.68 ?  293  THR A C   1 
ATOM   1275 O O   . THR A 1 293 ? 121.882 116.771 112.756 1.00 257.68 ?  293  THR A O   1 
ATOM   1276 C CB  . THR A 1 293 ? 120.797 116.076 115.292 1.00 257.68 ?  293  THR A CB  1 
ATOM   1277 O OG1 . THR A 1 293 ? 120.613 117.450 115.654 1.00 257.68 ?  293  THR A OG1 1 
ATOM   1278 C CG2 . THR A 1 293 ? 120.371 115.180 116.445 1.00 257.68 ?  293  THR A CG2 1 
ATOM   1279 N N   . SER A 1 294 ? 123.672 117.525 113.869 1.00 249.50 ?  294  SER A N   1 
ATOM   1280 C CA  . SER A 1 294 ? 123.993 118.485 112.822 1.00 249.50 ?  294  SER A CA  1 
ATOM   1281 C C   . SER A 1 294 ? 125.478 118.661 112.592 1.00 249.50 ?  294  SER A C   1 
ATOM   1282 O O   . SER A 1 294 ? 126.273 118.516 113.517 1.00 249.50 ?  294  SER A O   1 
ATOM   1283 C CB  . SER A 1 294 ? 123.366 119.841 113.143 1.00 249.50 ?  294  SER A CB  1 
ATOM   1284 O OG  . SER A 1 294 ? 123.307 120.657 111.987 1.00 249.50 ?  294  SER A OG  1 
ATOM   1285 N N   . THR A 1 295 ? 125.860 118.969 111.358 1.00 214.64 ?  295  THR A N   1 
ATOM   1286 C CA  . THR A 1 295 ? 127.262 119.239 111.064 1.00 214.64 ?  295  THR A CA  1 
ATOM   1287 C C   . THR A 1 295 ? 127.430 120.741 110.925 1.00 214.64 ?  295  THR A C   1 
ATOM   1288 O O   . THR A 1 295 ? 128.499 121.276 111.209 1.00 214.64 ?  295  THR A O   1 
ATOM   1289 C CB  . THR A 1 295 ? 127.726 118.533 109.776 1.00 214.64 ?  295  THR A CB  1 
ATOM   1290 O OG1 . THR A 1 295 ? 128.958 119.110 109.328 1.00 214.64 ?  295  THR A OG1 1 
ATOM   1291 C CG2 . THR A 1 295 ? 126.680 118.662 108.676 1.00 214.64 ?  295  THR A CG2 1 
ATOM   1292 N N   . TYR A 1 296 ? 126.374 121.426 110.499 1.00 214.03 ?  296  TYR A N   1 
ATOM   1293 C CA  . TYR A 1 296 ? 126.414 122.874 110.344 1.00 214.03 ?  296  TYR A CA  1 
ATOM   1294 C C   . TYR A 1 296 ? 125.077 123.405 110.803 1.00 214.03 ?  296  TYR A C   1 
ATOM   1295 O O   . TYR A 1 296 ? 124.091 123.308 110.079 1.00 214.03 ?  296  TYR A O   1 
ATOM   1296 C CB  . TYR A 1 296 ? 126.625 123.254 108.879 1.00 214.03 ?  296  TYR A CB  1 
ATOM   1297 C CG  . TYR A 1 296 ? 128.047 123.109 108.398 1.00 214.03 ?  296  TYR A CG  1 
ATOM   1298 C CD1 . TYR A 1 296 ? 129.026 124.006 108.793 1.00 214.03 ?  296  TYR A CD1 1 
ATOM   1299 C CD2 . TYR A 1 296 ? 128.410 122.074 107.548 1.00 214.03 ?  296  TYR A CD2 1 
ATOM   1300 C CE1 . TYR A 1 296 ? 130.329 123.876 108.358 1.00 214.03 ?  296  TYR A CE1 1 
ATOM   1301 C CE2 . TYR A 1 296 ? 129.710 121.935 107.108 1.00 214.03 ?  296  TYR A CE2 1 
ATOM   1302 C CZ  . TYR A 1 296 ? 130.665 122.839 107.516 1.00 214.03 ?  296  TYR A CZ  1 
ATOM   1303 O OH  . TYR A 1 296 ? 131.963 122.709 107.081 1.00 214.03 ?  296  TYR A OH  1 
ATOM   1304 N N   . PHE A 1 297 ? 125.048 123.986 111.986 1.00 202.07 ?  297  PHE A N   1 
ATOM   1305 C CA  . PHE A 1 297 ? 123.801 124.453 112.553 1.00 202.07 ?  297  PHE A CA  1 
ATOM   1306 C C   . PHE A 1 297 ? 123.536 125.920 112.264 1.00 202.07 ?  297  PHE A C   1 
ATOM   1307 O O   . PHE A 1 297 ? 124.464 126.665 111.976 1.00 202.07 ?  297  PHE A O   1 
ATOM   1308 C CB  . PHE A 1 297 ? 123.901 124.228 114.044 1.00 202.07 ?  297  PHE A CB  1 
ATOM   1309 C CG  . PHE A 1 297 ? 122.602 124.037 114.707 1.00 202.07 ?  297  PHE A CG  1 
ATOM   1310 C CD1 . PHE A 1 297 ? 122.037 122.802 114.759 1.00 202.07 ?  297  PHE A CD1 1 
ATOM   1311 C CD2 . PHE A 1 297 ? 121.959 125.091 115.293 1.00 202.07 ?  297  PHE A CD2 1 
ATOM   1312 C CE1 . PHE A 1 297 ? 120.831 122.623 115.377 1.00 202.07 ?  297  PHE A CE1 1 
ATOM   1313 C CE2 . PHE A 1 297 ? 120.741 124.927 115.892 1.00 202.07 ?  297  PHE A CE2 1 
ATOM   1314 C CZ  . PHE A 1 297 ? 120.157 123.691 115.924 1.00 202.07 ?  297  PHE A CZ  1 
ATOM   1315 N N   . ALA A 1 298 ? 122.276 126.343 112.339 1.00 189.57 ?  298  ALA A N   1 
ATOM   1316 C CA  . ALA A 1 298 ? 121.970 127.751 112.155 1.00 189.57 ?  298  ALA A CA  1 
ATOM   1317 C C   . ALA A 1 298 ? 121.614 128.350 113.499 1.00 189.57 ?  298  ALA A C   1 
ATOM   1318 O O   . ALA A 1 298 ? 120.919 127.724 114.291 1.00 189.57 ?  298  ALA A O   1 
ATOM   1319 C CB  . ALA A 1 298 ? 120.826 127.913 111.179 1.00 189.57 ?  298  ALA A CB  1 
ATOM   1320 N N   . VAL A 1 299 ? 122.085 129.561 113.767 1.00 207.10 ?  299  VAL A N   1 
ATOM   1321 C CA  . VAL A 1 299 ? 121.832 130.191 115.058 1.00 207.10 ?  299  VAL A CA  1 
ATOM   1322 C C   . VAL A 1 299 ? 120.352 130.427 115.319 1.00 207.10 ?  299  VAL A C   1 
ATOM   1323 O O   . VAL A 1 299 ? 119.921 130.440 116.467 1.00 207.10 ?  299  VAL A O   1 
ATOM   1324 C CB  . VAL A 1 299 ? 122.594 131.516 115.198 1.00 207.10 ?  299  VAL A CB  1 
ATOM   1325 C CG1 . VAL A 1 299 ? 123.437 131.504 116.463 1.00 207.10 ?  299  VAL A CG1 1 
ATOM   1326 C CG2 . VAL A 1 299 ? 123.463 131.755 113.976 1.00 207.10 ?  299  VAL A CG2 1 
ATOM   1327 N N   . ARG A 1 300 ? 119.569 130.616 114.265 1.00 246.42 ?  300  ARG A N   1 
ATOM   1328 C CA  . ARG A 1 300 ? 118.133 130.775 114.438 1.00 246.42 ?  300  ARG A CA  1 
ATOM   1329 C C   . ARG A 1 300 ? 117.554 129.543 115.103 1.00 246.42 ?  300  ARG A C   1 
ATOM   1330 O O   . ARG A 1 300 ? 116.790 129.657 116.052 1.00 246.42 ?  300  ARG A O   1 
ATOM   1331 C CB  . ARG A 1 300 ? 117.443 131.022 113.097 1.00 246.42 ?  300  ARG A CB  1 
ATOM   1332 C CG  . ARG A 1 300 ? 118.137 130.403 111.897 1.00 246.42 ?  300  ARG A CG  1 
ATOM   1333 C CD  . ARG A 1 300 ? 117.194 129.485 111.139 1.00 246.42 ?  300  ARG A CD  1 
ATOM   1334 N NE  . ARG A 1 300 ? 117.256 129.707 109.698 1.00 246.42 ?  300  ARG A NE  1 
ATOM   1335 C CZ  . ARG A 1 300 ? 117.563 128.769 108.809 1.00 246.42 ?  300  ARG A CZ  1 
ATOM   1336 N NH1 . ARG A 1 300 ? 117.594 129.063 107.518 1.00 246.42 1  300  ARG A NH1 1 
ATOM   1337 N NH2 . ARG A 1 300 ? 117.838 127.537 109.210 1.00 246.42 ?  300  ARG A NH2 1 
ATOM   1338 N N   . ASN A 1 301 ? 117.928 128.363 114.619 1.00 242.46 ?  301  ASN A N   1 
ATOM   1339 C CA  . ASN A 1 301 ? 117.430 127.122 115.191 1.00 242.46 ?  301  ASN A CA  1 
ATOM   1340 C C   . ASN A 1 301 ? 117.884 126.944 116.629 1.00 242.46 ?  301  ASN A C   1 
ATOM   1341 O O   . ASN A 1 301 ? 117.184 126.328 117.426 1.00 242.46 ?  301  ASN A O   1 
ATOM   1342 C CB  . ASN A 1 301 ? 117.874 125.936 114.345 1.00 242.46 ?  301  ASN A CB  1 
ATOM   1343 C CG  . ASN A 1 301 ? 117.229 125.928 112.980 1.00 242.46 ?  301  ASN A CG  1 
ATOM   1344 O OD1 . ASN A 1 301 ? 116.156 126.497 112.790 1.00 242.46 ?  301  ASN A OD1 1 
ATOM   1345 N ND2 . ASN A 1 301 ? 117.879 125.286 112.020 1.00 242.46 ?  301  ASN A ND2 1 
ATOM   1346 N N   . TYR A 1 302 ? 119.049 127.480 116.969 1.00 189.18 ?  302  TYR A N   1 
ATOM   1347 C CA  . TYR A 1 302 ? 119.530 127.404 118.342 1.00 189.18 ?  302  TYR A CA  1 
ATOM   1348 C C   . TYR A 1 302 ? 118.588 128.172 119.248 1.00 189.18 ?  302  TYR A C   1 
ATOM   1349 O O   . TYR A 1 302 ? 118.143 127.654 120.269 1.00 189.18 ?  302  TYR A O   1 
ATOM   1350 C CB  . TYR A 1 302 ? 120.949 127.964 118.443 1.00 189.18 ?  302  TYR A CB  1 
ATOM   1351 C CG  . TYR A 1 302 ? 121.428 128.233 119.851 1.00 189.18 ?  302  TYR A CG  1 
ATOM   1352 C CD1 . TYR A 1 302 ? 121.495 127.216 120.791 1.00 189.18 ?  302  TYR A CD1 1 
ATOM   1353 C CD2 . TYR A 1 302 ? 121.824 129.504 120.235 1.00 189.18 ?  302  TYR A CD2 1 
ATOM   1354 C CE1 . TYR A 1 302 ? 121.931 127.458 122.078 1.00 189.18 ?  302  TYR A CE1 1 
ATOM   1355 C CE2 . TYR A 1 302 ? 122.263 129.757 121.519 1.00 189.18 ?  302  TYR A CE2 1 
ATOM   1356 C CZ  . TYR A 1 302 ? 122.316 128.730 122.435 1.00 189.18 ?  302  TYR A CZ  1 
ATOM   1357 O OH  . TYR A 1 302 ? 122.754 128.974 123.716 1.00 189.18 ?  302  TYR A OH  1 
ATOM   1358 N N   . TRP A 1 303 ? 118.270 129.404 118.873 1.00 253.38 ?  303  TRP A N   1 
ATOM   1359 C CA  . TRP A 1 303 ? 117.370 130.216 119.679 1.00 253.38 ?  303  TRP A CA  1 
ATOM   1360 C C   . TRP A 1 303 ? 115.992 129.587 119.762 1.00 253.38 ?  303  TRP A C   1 
ATOM   1361 O O   . TRP A 1 303 ? 115.380 129.570 120.825 1.00 253.38 ?  303  TRP A O   1 
ATOM   1362 C CB  . TRP A 1 303 ? 117.262 131.626 119.107 1.00 253.38 ?  303  TRP A CB  1 
ATOM   1363 C CG  . TRP A 1 303 ? 118.572 132.328 118.996 1.00 253.38 ?  303  TRP A CG  1 
ATOM   1364 C CD1 . TRP A 1 303 ? 119.616 132.260 119.870 1.00 253.38 ?  303  TRP A CD1 1 
ATOM   1365 C CD2 . TRP A 1 303 ? 118.983 133.214 117.950 1.00 253.38 ?  303  TRP A CD2 1 
ATOM   1366 N NE1 . TRP A 1 303 ? 120.654 133.043 119.431 1.00 253.38 ?  303  TRP A NE1 1 
ATOM   1367 C CE2 . TRP A 1 303 ? 120.290 133.641 118.254 1.00 253.38 ?  303  TRP A CE2 1 
ATOM   1368 C CE3 . TRP A 1 303 ? 118.374 133.685 116.784 1.00 253.38 ?  303  TRP A CE3 1 
ATOM   1369 C CZ2 . TRP A 1 303 ? 120.997 134.517 117.436 1.00 253.38 ?  303  TRP A CZ2 1 
ATOM   1370 C CZ3 . TRP A 1 303 ? 119.078 134.553 115.973 1.00 253.38 ?  303  TRP A CZ3 1 
ATOM   1371 C CH2 . TRP A 1 303 ? 120.375 134.960 116.302 1.00 253.38 ?  303  TRP A CH2 1 
ATOM   1372 N N   . ARG A 1 304 ? 115.500 129.069 118.645 1.00 260.72 ?  304  ARG A N   1 
ATOM   1373 C CA  . ARG A 1 304 ? 114.177 128.466 118.623 1.00 260.72 ?  304  ARG A CA  1 
ATOM   1374 C C   . ARG A 1 304 ? 114.132 127.249 119.524 1.00 260.72 ?  304  ARG A C   1 
ATOM   1375 O O   . ARG A 1 304 ? 113.194 127.081 120.298 1.00 260.72 ?  304  ARG A O   1 
ATOM   1376 C CB  . ARG A 1 304 ? 113.799 128.082 117.195 1.00 260.72 ?  304  ARG A CB  1 
ATOM   1377 C CG  . ARG A 1 304 ? 113.549 129.264 116.275 1.00 260.72 ?  304  ARG A CG  1 
ATOM   1378 C CD  . ARG A 1 304 ? 112.434 128.982 115.283 1.00 260.72 ?  304  ARG A CD  1 
ATOM   1379 N NE  . ARG A 1 304 ? 112.587 127.693 114.616 1.00 260.72 ?  304  ARG A NE  1 
ATOM   1380 C CZ  . ARG A 1 304 ? 111.569 126.944 114.204 1.00 260.72 ?  304  ARG A CZ  1 
ATOM   1381 N NH1 . ARG A 1 304 ? 110.324 127.354 114.395 1.00 260.72 1  304  ARG A NH1 1 
ATOM   1382 N NH2 . ARG A 1 304 ? 111.793 125.784 113.604 1.00 260.72 ?  304  ARG A NH2 1 
ATOM   1383 N N   . GLY A 1 305 ? 115.148 126.402 119.436 1.00 246.55 ?  305  GLY A N   1 
ATOM   1384 C CA  . GLY A 1 305 ? 115.205 125.218 120.269 1.00 246.55 ?  305  GLY A CA  1 
ATOM   1385 C C   . GLY A 1 305 ? 115.285 125.577 121.731 1.00 246.55 ?  305  GLY A C   1 
ATOM   1386 O O   . GLY A 1 305 ? 114.669 124.923 122.561 1.00 246.55 ?  305  GLY A O   1 
ATOM   1387 N N   . PHE A 1 306 ? 116.033 126.625 122.052 1.00 235.42 ?  306  PHE A N   1 
ATOM   1388 C CA  . PHE A 1 306 ? 116.158 127.063 123.433 1.00 235.42 ?  306  PHE A CA  1 
ATOM   1389 C C   . PHE A 1 306 ? 114.831 127.563 123.985 1.00 235.42 ?  306  PHE A C   1 
ATOM   1390 O O   . PHE A 1 306 ? 114.474 127.250 125.114 1.00 235.42 ?  306  PHE A O   1 
ATOM   1391 C CB  . PHE A 1 306 ? 117.227 128.148 123.557 1.00 235.42 ?  306  PHE A CB  1 
ATOM   1392 C CG  . PHE A 1 306 ? 117.600 128.465 124.973 1.00 235.42 ?  306  PHE A CG  1 
ATOM   1393 C CD1 . PHE A 1 306 ? 117.956 127.454 125.850 1.00 235.42 ?  306  PHE A CD1 1 
ATOM   1394 C CD2 . PHE A 1 306 ? 117.589 129.770 125.429 1.00 235.42 ?  306  PHE A CD2 1 
ATOM   1395 C CE1 . PHE A 1 306 ? 118.294 127.742 127.156 1.00 235.42 ?  306  PHE A CE1 1 
ATOM   1396 C CE2 . PHE A 1 306 ? 117.928 130.065 126.735 1.00 235.42 ?  306  PHE A CE2 1 
ATOM   1397 C CZ  . PHE A 1 306 ? 118.283 129.049 127.600 1.00 235.42 ?  306  PHE A CZ  1 
ATOM   1398 N N   . PHE A 1 307 ? 114.095 128.331 123.191 1.00 255.37 ?  307  PHE A N   1 
ATOM   1399 C CA  . PHE A 1 307 ? 112.802 128.836 123.631 1.00 255.37 ?  307  PHE A CA  1 
ATOM   1400 C C   . PHE A 1 307 ? 111.845 127.691 123.905 1.00 255.37 ?  307  PHE A C   1 
ATOM   1401 O O   . PHE A 1 307 ? 111.165 127.668 124.929 1.00 255.37 ?  307  PHE A O   1 
ATOM   1402 C CB  . PHE A 1 307 ? 112.200 129.775 122.589 1.00 255.37 ?  307  PHE A CB  1 
ATOM   1403 C CG  . PHE A 1 307 ? 110.832 130.277 122.948 1.00 255.37 ?  307  PHE A CG  1 
ATOM   1404 C CD1 . PHE A 1 307 ? 110.640 131.052 124.078 1.00 255.37 ?  307  PHE A CD1 1 
ATOM   1405 C CD2 . PHE A 1 307 ? 109.738 129.969 122.162 1.00 255.37 ?  307  PHE A CD2 1 
ATOM   1406 C CE1 . PHE A 1 307 ? 109.381 131.511 124.414 1.00 255.37 ?  307  PHE A CE1 1 
ATOM   1407 C CE2 . PHE A 1 307 ? 108.478 130.424 122.489 1.00 255.37 ?  307  PHE A CE2 1 
ATOM   1408 C CZ  . PHE A 1 307 ? 108.299 131.197 123.617 1.00 255.37 ?  307  PHE A CZ  1 
ATOM   1409 N N   . ALA A 1 308 ? 111.791 126.733 122.993 1.00 251.09 ?  308  ALA A N   1 
ATOM   1410 C CA  . ALA A 1 308 ? 110.887 125.614 123.165 1.00 251.09 ?  308  ALA A CA  1 
ATOM   1411 C C   . ALA A 1 308 ? 111.288 124.758 124.358 1.00 251.09 ?  308  ALA A C   1 
ATOM   1412 O O   . ALA A 1 308 ? 110.430 124.244 125.070 1.00 251.09 ?  308  ALA A O   1 
ATOM   1413 C CB  . ALA A 1 308 ? 110.842 124.790 121.899 1.00 251.09 ?  308  ALA A CB  1 
ATOM   1414 N N   . ALA A 1 309 ? 112.586 124.618 124.593 1.00 248.92 ?  309  ALA A N   1 
ATOM   1415 C CA  . ALA A 1 309 ? 113.063 123.812 125.709 1.00 248.92 ?  309  ALA A CA  1 
ATOM   1416 C C   . ALA A 1 309 ? 112.852 124.495 127.051 1.00 248.92 ?  309  ALA A C   1 
ATOM   1417 O O   . ALA A 1 309 ? 112.682 123.825 128.065 1.00 248.92 ?  309  ALA A O   1 
ATOM   1418 C CB  . ALA A 1 309 ? 114.525 123.453 125.520 1.00 248.92 ?  309  ALA A CB  1 
ATOM   1419 N N   . THR A 1 310 ? 112.861 125.822 127.071 1.00 278.73 ?  310  THR A N   1 
ATOM   1420 C CA  . THR A 1 310 ? 112.593 126.531 128.315 1.00 278.73 ?  310  THR A CA  1 
ATOM   1421 C C   . THR A 1 310 ? 111.122 126.441 128.643 1.00 278.73 ?  310  THR A C   1 
ATOM   1422 O O   . THR A 1 310 ? 110.749 126.441 129.810 1.00 278.73 ?  310  THR A O   1 
ATOM   1423 C CB  . THR A 1 310 ? 113.027 128.007 128.279 1.00 278.73 ?  310  THR A CB  1 
ATOM   1424 O OG1 . THR A 1 310 ? 112.582 128.617 127.064 1.00 278.73 ?  310  THR A OG1 1 
ATOM   1425 C CG2 . THR A 1 310 ? 114.537 128.118 128.379 1.00 278.73 ?  310  THR A CG2 1 
ATOM   1426 N N   . PHE A 1 311 ? 110.276 126.354 127.625 1.00 245.67 ?  311  PHE A N   1 
ATOM   1427 C CA  . PHE A 1 311 ? 108.859 126.171 127.890 1.00 245.67 ?  311  PHE A CA  1 
ATOM   1428 C C   . PHE A 1 311 ? 108.628 124.763 128.401 1.00 245.67 ?  311  PHE A C   1 
ATOM   1429 O O   . PHE A 1 311 ? 107.786 124.550 129.261 1.00 245.67 ?  311  PHE A O   1 
ATOM   1430 C CB  . PHE A 1 311 ? 108.004 126.445 126.657 1.00 245.67 ?  311  PHE A CB  1 
ATOM   1431 C CG  . PHE A 1 311 ? 106.562 126.693 126.979 1.00 245.67 ?  311  PHE A CG  1 
ATOM   1432 C CD1 . PHE A 1 311 ? 106.156 127.914 127.484 1.00 245.67 ?  311  PHE A CD1 1 
ATOM   1433 C CD2 . PHE A 1 311 ? 105.618 125.699 126.805 1.00 245.67 ?  311  PHE A CD2 1 
ATOM   1434 C CE1 . PHE A 1 311 ? 104.831 128.146 127.794 1.00 245.67 ?  311  PHE A CE1 1 
ATOM   1435 C CE2 . PHE A 1 311 ? 104.291 125.922 127.114 1.00 245.67 ?  311  PHE A CE2 1 
ATOM   1436 C CZ  . PHE A 1 311 ? 103.897 127.147 127.610 1.00 245.67 ?  311  PHE A CZ  1 
ATOM   1437 N N   . SER A 1 312 ? 109.379 123.798 127.884 1.00 245.26 ?  312  SER A N   1 
ATOM   1438 C CA  . SER A 1 312 ? 109.266 122.429 128.371 1.00 245.26 ?  312  SER A CA  1 
ATOM   1439 C C   . SER A 1 312 ? 109.627 122.400 129.841 1.00 245.26 ?  312  SER A C   1 
ATOM   1440 O O   . SER A 1 312 ? 108.944 121.767 130.638 1.00 245.26 ?  312  SER A O   1 
ATOM   1441 C CB  . SER A 1 312 ? 110.187 121.502 127.582 1.00 245.26 ?  312  SER A CB  1 
ATOM   1442 O OG  . SER A 1 312 ? 109.525 120.308 127.212 1.00 245.26 ?  312  SER A OG  1 
ATOM   1443 N N   . ALA A 1 313 ? 110.692 123.099 130.208 1.00 226.87 ?  313  ALA A N   1 
ATOM   1444 C CA  . ALA A 1 313 ? 111.108 123.152 131.602 1.00 226.87 ?  313  ALA A CA  1 
ATOM   1445 C C   . ALA A 1 313 ? 110.083 123.870 132.457 1.00 226.87 ?  313  ALA A C   1 
ATOM   1446 O O   . ALA A 1 313 ? 109.860 123.493 133.600 1.00 226.87 ?  313  ALA A O   1 
ATOM   1447 C CB  . ALA A 1 313 ? 112.457 123.829 131.721 1.00 226.87 ?  313  ALA A CB  1 
ATOM   1448 N N   . PHE A 1 314 ? 109.461 124.907 131.912 1.00 245.76 ?  314  PHE A N   1 
ATOM   1449 C CA  . PHE A 1 314 ? 108.431 125.627 132.643 1.00 245.76 ?  314  PHE A CA  1 
ATOM   1450 C C   . PHE A 1 314 ? 107.288 124.684 132.966 1.00 245.76 ?  314  PHE A C   1 
ATOM   1451 O O   . PHE A 1 314 ? 106.830 124.629 134.102 1.00 245.76 ?  314  PHE A O   1 
ATOM   1452 C CB  . PHE A 1 314 ? 107.939 126.819 131.821 1.00 245.76 ?  314  PHE A CB  1 
ATOM   1453 C CG  . PHE A 1 314 ? 106.616 127.369 132.267 1.00 245.76 ?  314  PHE A CG  1 
ATOM   1454 C CD1 . PHE A 1 314 ? 106.508 128.074 133.453 1.00 245.76 ?  314  PHE A CD1 1 
ATOM   1455 C CD2 . PHE A 1 314 ? 105.483 127.196 131.490 1.00 245.76 ?  314  PHE A CD2 1 
ATOM   1456 C CE1 . PHE A 1 314 ? 105.293 128.585 133.863 1.00 245.76 ?  314  PHE A CE1 1 
ATOM   1457 C CE2 . PHE A 1 314 ? 104.265 127.702 131.894 1.00 245.76 ?  314  PHE A CE2 1 
ATOM   1458 C CZ  . PHE A 1 314 ? 104.170 128.399 133.082 1.00 245.76 ?  314  PHE A CZ  1 
ATOM   1459 N N   . VAL A 1 315 ? 106.831 123.931 131.972 1.00 246.86 ?  315  VAL A N   1 
ATOM   1460 C CA  . VAL A 1 315 ? 105.739 122.993 132.189 1.00 246.86 ?  315  VAL A CA  1 
ATOM   1461 C C   . VAL A 1 315 ? 106.150 121.953 133.214 1.00 246.86 ?  315  VAL A C   1 
ATOM   1462 O O   . VAL A 1 315 ? 105.365 121.595 134.080 1.00 246.86 ?  315  VAL A O   1 
ATOM   1463 C CB  . VAL A 1 315 ? 105.292 122.326 130.875 1.00 246.86 ?  315  VAL A CB  1 
ATOM   1464 C CG1 . VAL A 1 315 ? 104.140 121.365 131.120 1.00 246.86 ?  315  VAL A CG1 1 
ATOM   1465 C CG2 . VAL A 1 315 ? 104.867 123.384 129.874 1.00 246.86 ?  315  VAL A CG2 1 
ATOM   1466 N N   . PHE A 1 316 ? 107.391 121.491 133.144 1.00 202.01 ?  316  PHE A N   1 
ATOM   1467 C CA  . PHE A 1 316 ? 107.884 120.521 134.113 1.00 202.01 ?  316  PHE A CA  1 
ATOM   1468 C C   . PHE A 1 316 ? 107.824 121.056 135.534 1.00 202.01 ?  316  PHE A C   1 
ATOM   1469 O O   . PHE A 1 316 ? 107.486 120.323 136.456 1.00 202.01 ?  316  PHE A O   1 
ATOM   1470 C CB  . PHE A 1 316 ? 109.314 120.115 133.780 1.00 202.01 ?  316  PHE A CB  1 
ATOM   1471 C CG  . PHE A 1 316 ? 109.409 118.899 132.912 1.00 202.01 ?  316  PHE A CG  1 
ATOM   1472 C CD1 . PHE A 1 316 ? 108.618 117.792 133.162 1.00 202.01 ?  316  PHE A CD1 1 
ATOM   1473 C CD2 . PHE A 1 316 ? 110.290 118.863 131.848 1.00 202.01 ?  316  PHE A CD2 1 
ATOM   1474 C CE1 . PHE A 1 316 ? 108.706 116.669 132.366 1.00 202.01 ?  316  PHE A CE1 1 
ATOM   1475 C CE2 . PHE A 1 316 ? 110.381 117.745 131.047 1.00 202.01 ?  316  PHE A CE2 1 
ATOM   1476 C CZ  . PHE A 1 316 ? 109.589 116.646 131.307 1.00 202.01 ?  316  PHE A CZ  1 
ATOM   1477 N N   . ARG A 1 317 ? 108.151 122.330 135.717 1.00 206.32 ?  317  ARG A N   1 
ATOM   1478 C CA  . ARG A 1 317 ? 108.108 122.936 137.045 1.00 206.32 ?  317  ARG A CA  1 
ATOM   1479 C C   . ARG A 1 317 ? 106.679 123.009 137.546 1.00 206.32 ?  317  ARG A C   1 
ATOM   1480 O O   . ARG A 1 317 ? 106.415 122.734 138.711 1.00 206.32 ?  317  ARG A O   1 
ATOM   1481 C CB  . ARG A 1 317 ? 108.721 124.336 137.031 1.00 206.32 ?  317  ARG A CB  1 
ATOM   1482 C CG  . ARG A 1 317 ? 110.217 124.374 136.767 1.00 206.32 ?  317  ARG A CG  1 
ATOM   1483 C CD  . ARG A 1 317 ? 110.922 123.145 137.314 1.00 206.32 ?  317  ARG A CD  1 
ATOM   1484 N NE  . ARG A 1 317 ? 112.318 123.416 137.640 1.00 206.32 ?  317  ARG A NE  1 
ATOM   1485 C CZ  . ARG A 1 317 ? 112.889 123.086 138.793 1.00 206.32 ?  317  ARG A CZ  1 
ATOM   1486 N NH1 . ARG A 1 317 ? 112.182 122.470 139.731 1.00 206.32 1  317  ARG A NH1 1 
ATOM   1487 N NH2 . ARG A 1 317 ? 114.166 123.370 139.009 1.00 206.32 ?  317  ARG A NH2 1 
ATOM   1488 N N   . VAL A 1 318 ? 105.753 123.380 136.670 1.00 221.29 ?  318  VAL A N   1 
ATOM   1489 C CA  . VAL A 1 318 ? 104.349 123.435 137.051 1.00 221.29 ?  318  VAL A CA  1 
ATOM   1490 C C   . VAL A 1 318 ? 103.844 122.039 137.390 1.00 221.29 ?  318  VAL A C   1 
ATOM   1491 O O   . VAL A 1 318 ? 103.135 121.854 138.377 1.00 221.29 ?  318  VAL A O   1 
ATOM   1492 C CB  . VAL A 1 318 ? 103.496 124.051 135.931 1.00 221.29 ?  318  VAL A CB  1 
ATOM   1493 C CG1 . VAL A 1 318 ? 102.034 124.110 136.336 1.00 221.29 ?  318  VAL A CG1 1 
ATOM   1494 C CG2 . VAL A 1 318 ? 103.999 125.443 135.599 1.00 221.29 ?  318  VAL A CG2 1 
ATOM   1495 N N   . LEU A 1 319 ? 104.227 121.049 136.591 1.00 214.33 ?  319  LEU A N   1 
ATOM   1496 C CA  . LEU A 1 319 ? 103.811 119.676 136.846 1.00 214.33 ?  319  LEU A CA  1 
ATOM   1497 C C   . LEU A 1 319 ? 104.371 119.192 138.168 1.00 214.33 ?  319  LEU A C   1 
ATOM   1498 O O   . LEU A 1 319 ? 103.717 118.437 138.880 1.00 214.33 ?  319  LEU A O   1 
ATOM   1499 C CB  . LEU A 1 319 ? 104.273 118.754 135.721 1.00 214.33 ?  319  LEU A CB  1 
ATOM   1500 C CG  . LEU A 1 319 ? 103.399 118.687 134.471 1.00 214.33 ?  319  LEU A CG  1 
ATOM   1501 C CD1 . LEU A 1 319 ? 104.218 118.203 133.285 1.00 214.33 ?  319  LEU A CD1 1 
ATOM   1502 C CD2 . LEU A 1 319 ? 102.204 117.778 134.709 1.00 214.33 ?  319  LEU A CD2 1 
ATOM   1503 N N   . ALA A 1 320 ? 105.575 119.638 138.504 1.00 212.63 ?  320  ALA A N   1 
ATOM   1504 C CA  . ALA A 1 320 ? 106.180 119.256 139.770 1.00 212.63 ?  320  ALA A CA  1 
ATOM   1505 C C   . ALA A 1 320 ? 105.339 119.789 140.907 1.00 212.63 ?  320  ALA A C   1 
ATOM   1506 O O   . ALA A 1 320 ? 104.981 119.048 141.811 1.00 212.63 ?  320  ALA A O   1 
ATOM   1507 C CB  . ALA A 1 320 ? 107.600 119.781 139.866 1.00 212.63 ?  320  ALA A CB  1 
ATOM   1508 N N   . VAL A 1 321 ? 105.010 121.072 140.861 1.00 232.14 ?  321  VAL A N   1 
ATOM   1509 C CA  . VAL A 1 321 ? 104.174 121.666 141.894 1.00 232.14 ?  321  VAL A CA  1 
ATOM   1510 C C   . VAL A 1 321 ? 102.873 120.892 142.013 1.00 232.14 ?  321  VAL A C   1 
ATOM   1511 O O   . VAL A 1 321 ? 102.483 120.488 143.109 1.00 232.14 ?  321  VAL A O   1 
ATOM   1512 C CB  . VAL A 1 321 ? 103.881 123.147 141.589 1.00 232.14 ?  321  VAL A CB  1 
ATOM   1513 C CG1 . VAL A 1 321 ? 102.861 123.713 142.566 1.00 232.14 ?  321  VAL A CG1 1 
ATOM   1514 C CG2 . VAL A 1 321 ? 105.166 123.957 141.635 1.00 232.14 ?  321  VAL A CG2 1 
ATOM   1515 N N   . TRP A 1 322 ? 102.245 120.603 140.882 1.00 263.41 ?  322  TRP A N   1 
ATOM   1516 C CA  . TRP A 1 322 ? 100.976 119.882 140.883 1.00 263.41 ?  322  TRP A CA  1 
ATOM   1517 C C   . TRP A 1 322 ? 101.034 118.501 141.497 1.00 263.41 ?  322  TRP A C   1 
ATOM   1518 O O   . TRP A 1 322 ? 100.270 118.198 142.409 1.00 263.41 ?  322  TRP A O   1 
ATOM   1519 C CB  . TRP A 1 322 ? 100.482 119.723 139.452 1.00 263.41 ?  322  TRP A CB  1 
ATOM   1520 C CG  . TRP A 1 322 ? 99.805  120.911 138.897 1.00 263.41 ?  322  TRP A CG  1 
ATOM   1521 C CD1 . TRP A 1 322 ? 99.277  121.957 139.591 1.00 263.41 ?  322  TRP A CD1 1 
ATOM   1522 C CD2 . TRP A 1 322 ? 99.567  121.180 137.516 1.00 263.41 ?  322  TRP A CD2 1 
ATOM   1523 N NE1 . TRP A 1 322 ? 98.725  122.867 138.723 1.00 263.41 ?  322  TRP A NE1 1 
ATOM   1524 C CE2 . TRP A 1 322 ? 98.889  122.411 137.442 1.00 263.41 ?  322  TRP A CE2 1 
ATOM   1525 C CE3 . TRP A 1 322 ? 99.862  120.499 136.333 1.00 263.41 ?  322  TRP A CE3 1 
ATOM   1526 C CZ2 . TRP A 1 322 ? 98.500  122.975 136.230 1.00 263.41 ?  322  TRP A CZ2 1 
ATOM   1527 C CZ3 . TRP A 1 322 ? 99.479  121.060 135.132 1.00 263.41 ?  322  TRP A CZ3 1 
ATOM   1528 C CH2 . TRP A 1 322 ? 98.805  122.286 135.088 1.00 263.41 ?  322  TRP A CH2 1 
ATOM   1529 N N   . ASN A 1 323 ? 101.929 117.651 141.010 1.00 237.10 ?  323  ASN A N   1 
ATOM   1530 C CA  . ASN A 1 323 ? 101.942 116.264 141.475 1.00 237.10 ?  323  ASN A CA  1 
ATOM   1531 C C   . ASN A 1 323 ? 103.040 115.868 142.448 1.00 237.10 ?  323  ASN A C   1 
ATOM   1532 O O   . ASN A 1 323 ? 103.157 114.688 142.774 1.00 237.10 ?  323  ASN A O   1 
ATOM   1533 C CB  . ASN A 1 323 ? 101.968 115.325 140.269 1.00 237.10 ?  323  ASN A CB  1 
ATOM   1534 C CG  . ASN A 1 323 ? 101.012 115.758 139.175 1.00 237.10 ?  323  ASN A CG  1 
ATOM   1535 O OD1 . ASN A 1 323 ? 101.397 116.453 138.234 1.00 237.10 ?  323  ASN A OD1 1 
ATOM   1536 N ND2 . ASN A 1 323 ? 99.757  115.345 139.292 1.00 237.10 ?  323  ASN A ND2 1 
ATOM   1537 N N   . LYS A 1 324 ? 103.808 116.839 142.930 1.00 232.23 ?  324  LYS A N   1 
ATOM   1538 C CA  . LYS A 1 324 ? 104.874 116.586 143.912 1.00 232.23 ?  324  LYS A CA  1 
ATOM   1539 C C   . LYS A 1 324 ? 105.729 115.365 143.645 1.00 232.23 ?  324  LYS A C   1 
ATOM   1540 O O   . LYS A 1 324 ? 106.599 115.408 142.778 1.00 232.23 ?  324  LYS A O   1 
ATOM   1541 C CB  . LYS A 1 324 ? 104.304 116.557 145.332 1.00 232.23 ?  324  LYS A CB  1 
ATOM   1542 C CG  . LYS A 1 324 ? 104.168 117.938 145.948 1.00 232.23 ?  324  LYS A CG  1 
ATOM   1543 C CD  . LYS A 1 324 ? 105.340 118.823 145.554 1.00 232.23 ?  324  LYS A CD  1 
ATOM   1544 C CE  . LYS A 1 324 ? 104.982 120.297 145.632 1.00 232.23 ?  324  LYS A CE  1 
ATOM   1545 N NZ  . LYS A 1 324 ? 105.993 121.136 144.933 1.00 232.23 1  324  LYS A NZ  1 
ATOM   1546 N N   . ASP A 1 325 ? 105.499 114.291 144.395 1.00 221.52 ?  325  ASP A N   1 
ATOM   1547 C CA  . ASP A 1 325 ? 106.272 113.059 144.234 1.00 221.52 ?  325  ASP A CA  1 
ATOM   1548 C C   . ASP A 1 325 ? 106.294 112.564 142.800 1.00 221.52 ?  325  ASP A C   1 
ATOM   1549 O O   . ASP A 1 325 ? 107.336 112.657 142.147 1.00 221.52 ?  325  ASP A O   1 
ATOM   1550 C CB  . ASP A 1 325 ? 105.692 111.975 145.140 1.00 221.52 ?  325  ASP A CB  1 
ATOM   1551 C CG  . ASP A 1 325 ? 104.308 112.329 145.649 1.00 221.52 ?  325  ASP A CG  1 
ATOM   1552 O OD1 . ASP A 1 325 ? 103.328 112.117 144.905 1.00 221.52 ?  325  ASP A OD1 1 
ATOM   1553 O OD2 . ASP A 1 325 ? 104.201 112.826 146.790 1.00 221.52 -1 325  ASP A OD2 1 
ATOM   1554 N N   . ALA A 1 326 ? 105.173 112.019 142.323 1.00 234.28 ?  326  ALA A N   1 
ATOM   1555 C CA  . ALA A 1 326 ? 105.062 111.543 140.938 1.00 234.28 ?  326  ALA A CA  1 
ATOM   1556 C C   . ALA A 1 326 ? 106.343 110.965 140.370 1.00 234.28 ?  326  ALA A C   1 
ATOM   1557 O O   . ALA A 1 326 ? 106.799 109.903 140.798 1.00 234.28 ?  326  ALA A O   1 
ATOM   1558 C CB  . ALA A 1 326 ? 104.572 112.673 140.055 1.00 234.28 ?  326  ALA A CB  1 
ATOM   1559 N N   . VAL A 1 327 ? 106.917 111.643 139.384 1.00 229.27 ?  327  VAL A N   1 
ATOM   1560 C CA  . VAL A 1 327 ? 108.204 111.213 138.859 1.00 229.27 ?  327  VAL A CA  1 
ATOM   1561 C C   . VAL A 1 327 ? 109.176 112.331 139.192 1.00 229.27 ?  327  VAL A C   1 
ATOM   1562 O O   . VAL A 1 327 ? 108.885 113.507 138.962 1.00 229.27 ?  327  VAL A O   1 
ATOM   1563 C CB  . VAL A 1 327 ? 108.160 110.929 137.342 1.00 229.27 ?  327  VAL A CB  1 
ATOM   1564 C CG1 . VAL A 1 327 ? 107.298 111.938 136.607 1.00 229.27 ?  327  VAL A CG1 1 
ATOM   1565 C CG2 . VAL A 1 327 ? 109.554 110.846 136.738 1.00 229.27 ?  327  VAL A CG2 1 
ATOM   1566 N N   . THR A 1 328 ? 110.307 111.994 139.793 1.00 244.65 ?  328  THR A N   1 
ATOM   1567 C CA  . THR A 1 328 ? 111.309 113.009 140.056 1.00 244.65 ?  328  THR A CA  1 
ATOM   1568 C C   . THR A 1 328 ? 112.126 113.135 138.794 1.00 244.65 ?  328  THR A C   1 
ATOM   1569 O O   . THR A 1 328 ? 113.168 112.496 138.675 1.00 244.65 ?  328  THR A O   1 
ATOM   1570 C CB  . THR A 1 328 ? 112.215 112.610 141.222 1.00 244.65 ?  328  THR A CB  1 
ATOM   1571 O OG1 . THR A 1 328 ? 112.001 111.228 141.534 1.00 244.65 ?  328  THR A OG1 1 
ATOM   1572 C CG2 . THR A 1 328 ? 111.904 113.452 142.445 1.00 244.65 ?  328  THR A CG2 1 
ATOM   1573 N N   . ILE A 1 329 ? 111.650 113.935 137.843 1.00 242.79 ?  329  ILE A N   1 
ATOM   1574 C CA  . ILE A 1 329 ? 112.333 114.088 136.563 1.00 242.79 ?  329  ILE A CA  1 
ATOM   1575 C C   . ILE A 1 329 ? 113.743 114.582 136.770 1.00 242.79 ?  329  ILE A C   1 
ATOM   1576 O O   . ILE A 1 329 ? 113.944 115.776 136.995 1.00 242.79 ?  329  ILE A O   1 
ATOM   1577 C CB  . ILE A 1 329 ? 111.590 115.073 135.639 1.00 242.79 ?  329  ILE A CB  1 
ATOM   1578 C CG1 . ILE A 1 329 ? 110.076 114.968 135.847 1.00 242.79 ?  329  ILE A CG1 1 
ATOM   1579 C CG2 . ILE A 1 329 ? 111.953 114.815 134.184 1.00 242.79 ?  329  ILE A CG2 1 
ATOM   1580 C CD1 . ILE A 1 329 ? 109.442 116.212 136.435 1.00 242.79 ?  329  ILE A CD1 1 
ATOM   1581 N N   . THR A 1 330 ? 114.719 113.676 136.708 1.00 225.17 ?  330  THR A N   1 
ATOM   1582 C CA  . THR A 1 330 ? 116.129 114.025 136.909 1.00 225.17 ?  330  THR A CA  1 
ATOM   1583 C C   . THR A 1 330 ? 116.410 114.992 138.063 1.00 225.17 ?  330  THR A C   1 
ATOM   1584 O O   . THR A 1 330 ? 117.294 115.837 137.969 1.00 225.17 ?  330  THR A O   1 
ATOM   1585 C CB  . THR A 1 330 ? 116.778 114.506 135.595 1.00 225.17 ?  330  THR A CB  1 
ATOM   1586 O OG1 . THR A 1 330 ? 116.286 115.808 135.251 1.00 225.17 ?  330  THR A OG1 1 
ATOM   1587 C CG2 . THR A 1 330 ? 116.469 113.532 134.468 1.00 225.17 ?  330  THR A CG2 1 
ATOM   1588 N N   . ALA A 1 331 ? 115.680 114.847 139.164 1.00 212.90 ?  331  ALA A N   1 
ATOM   1589 C CA  . ALA A 1 331 ? 115.863 115.736 140.304 1.00 212.90 ?  331  ALA A CA  1 
ATOM   1590 C C   . ALA A 1 331 ? 116.663 115.013 141.362 1.00 212.90 ?  331  ALA A C   1 
ATOM   1591 O O   . ALA A 1 331 ? 117.100 115.616 142.340 1.00 212.90 ?  331  ALA A O   1 
ATOM   1592 C CB  . ALA A 1 331 ? 114.520 116.177 140.856 1.00 212.90 ?  331  ALA A CB  1 
ATOM   1593 N N   . LEU A 1 332 ? 116.869 113.715 141.164 1.00 197.67 ?  332  LEU A N   1 
ATOM   1594 C CA  . LEU A 1 332 ? 117.666 112.940 142.102 1.00 197.67 ?  332  LEU A CA  1 
ATOM   1595 C C   . LEU A 1 332 ? 119.129 113.124 141.785 1.00 197.67 ?  332  LEU A C   1 
ATOM   1596 O O   . LEU A 1 332 ? 119.995 112.760 142.578 1.00 197.67 ?  332  LEU A O   1 
ATOM   1597 C CB  . LEU A 1 332 ? 117.324 111.461 141.988 1.00 197.67 ?  332  LEU A CB  1 
ATOM   1598 C CG  . LEU A 1 332 ? 115.873 111.095 141.704 1.00 197.67 ?  332  LEU A CG  1 
ATOM   1599 C CD1 . LEU A 1 332 ? 115.817 110.017 140.637 1.00 197.67 ?  332  LEU A CD1 1 
ATOM   1600 C CD2 . LEU A 1 332 ? 115.225 110.606 142.987 1.00 197.67 ?  332  LEU A CD2 1 
ATOM   1601 N N   . PHE A 1 333 ? 119.417 113.698 140.624 1.00 196.18 ?  333  PHE A N   1 
ATOM   1602 C CA  . PHE A 1 333 ? 120.801 113.849 140.210 1.00 196.18 ?  333  PHE A CA  1 
ATOM   1603 C C   . PHE A 1 333 ? 121.309 115.191 140.682 1.00 196.18 ?  333  PHE A C   1 
ATOM   1604 O O   . PHE A 1 333 ? 122.466 115.527 140.459 1.00 196.18 ?  333  PHE A O   1 
ATOM   1605 C CB  . PHE A 1 333 ? 120.946 113.713 138.693 1.00 196.18 ?  333  PHE A CB  1 
ATOM   1606 C CG  . PHE A 1 333 ? 120.266 112.497 138.116 1.00 196.18 ?  333  PHE A CG  1 
ATOM   1607 C CD1 . PHE A 1 333 ? 120.148 111.320 138.842 1.00 196.18 ?  333  PHE A CD1 1 
ATOM   1608 C CD2 . PHE A 1 333 ? 119.762 112.530 136.832 1.00 196.18 ?  333  PHE A CD2 1 
ATOM   1609 C CE1 . PHE A 1 333 ? 119.511 110.222 138.311 1.00 196.18 ?  333  PHE A CE1 1 
ATOM   1610 C CE2 . PHE A 1 333 ? 119.138 111.426 136.289 1.00 196.18 ?  333  PHE A CE2 1 
ATOM   1611 C CZ  . PHE A 1 333 ? 119.015 110.271 137.029 1.00 196.18 ?  333  PHE A CZ  1 
ATOM   1612 N N   . ARG A 1 334 ? 120.447 115.964 141.332 1.00 237.12 ?  334  ARG A N   1 
ATOM   1613 C CA  . ARG A 1 334 ? 120.872 117.239 141.881 1.00 237.12 ?  334  ARG A CA  1 
ATOM   1614 C C   . ARG A 1 334 ? 121.752 116.963 143.074 1.00 237.12 ?  334  ARG A C   1 
ATOM   1615 O O   . ARG A 1 334 ? 121.293 116.423 144.078 1.00 237.12 ?  334  ARG A O   1 
ATOM   1616 C CB  . ARG A 1 334 ? 119.672 118.100 142.256 1.00 237.12 ?  334  ARG A CB  1 
ATOM   1617 C CG  . ARG A 1 334 ? 119.345 119.157 141.217 1.00 237.12 ?  334  ARG A CG  1 
ATOM   1618 C CD  . ARG A 1 334 ? 118.623 118.552 140.025 1.00 237.12 ?  334  ARG A CD  1 
ATOM   1619 N NE  . ARG A 1 334 ? 118.907 119.264 138.784 1.00 237.12 ?  334  ARG A NE  1 
ATOM   1620 C CZ  . ARG A 1 334 ? 118.055 119.359 137.769 1.00 237.12 ?  334  ARG A CZ  1 
ATOM   1621 N NH1 . ARG A 1 334 ? 116.861 118.786 137.849 1.00 237.12 1  334  ARG A NH1 1 
ATOM   1622 N NH2 . ARG A 1 334 ? 118.393 120.025 136.673 1.00 237.12 ?  334  ARG A NH2 1 
ATOM   1623 N N   . THR A 1 335 ? 123.024 117.321 142.973 1.00 241.14 ?  335  THR A N   1 
ATOM   1624 C CA  . THR A 1 335 ? 123.955 117.006 144.043 1.00 241.14 ?  335  THR A CA  1 
ATOM   1625 C C   . THR A 1 335 ? 124.092 118.086 145.092 1.00 241.14 ?  335  THR A C   1 
ATOM   1626 O O   . THR A 1 335 ? 123.658 119.217 144.884 1.00 241.14 ?  335  THR A O   1 
ATOM   1627 C CB  . THR A 1 335 ? 125.347 116.746 143.481 1.00 241.14 ?  335  THR A CB  1 
ATOM   1628 O OG1 . THR A 1 335 ? 125.875 117.963 142.943 1.00 241.14 ?  335  THR A OG1 1 
ATOM   1629 C CG2 . THR A 1 335 ? 125.282 115.705 142.404 1.00 241.14 ?  335  THR A CG2 1 
ATOM   1630 N N   . ASN A 1 336 ? 124.707 117.740 146.218 1.00 222.54 ?  336  ASN A N   1 
ATOM   1631 C CA  . ASN A 1 336 ? 124.887 118.698 147.298 1.00 222.54 ?  336  ASN A CA  1 
ATOM   1632 C C   . ASN A 1 336 ? 126.357 118.799 147.647 1.00 222.54 ?  336  ASN A C   1 
ATOM   1633 O O   . ASN A 1 336 ? 126.747 118.563 148.789 1.00 222.54 ?  336  ASN A O   1 
ATOM   1634 C CB  . ASN A 1 336 ? 124.088 118.266 148.526 1.00 222.54 ?  336  ASN A CB  1 
ATOM   1635 C CG  . ASN A 1 336 ? 123.379 116.941 148.324 1.00 222.54 ?  336  ASN A CG  1 
ATOM   1636 O OD1 . ASN A 1 336 ? 122.275 116.892 147.782 1.00 222.54 ?  336  ASN A OD1 1 
ATOM   1637 N ND2 . ASN A 1 336 ? 124.010 115.858 148.761 1.00 222.54 ?  336  ASN A ND2 1 
ATOM   1638 N N   . PHE A 1 337 ? 127.180 119.151 146.667 1.00 245.34 ?  337  PHE A N   1 
ATOM   1639 C CA  . PHE A 1 337 ? 128.616 119.221 146.898 1.00 245.34 ?  337  PHE A CA  1 
ATOM   1640 C C   . PHE A 1 337 ? 129.032 120.589 147.392 1.00 245.34 ?  337  PHE A C   1 
ATOM   1641 O O   . PHE A 1 337 ? 128.847 121.587 146.700 1.00 245.34 ?  337  PHE A O   1 
ATOM   1642 C CB  . PHE A 1 337 ? 129.388 118.889 145.622 1.00 245.34 ?  337  PHE A CB  1 
ATOM   1643 C CG  . PHE A 1 337 ? 129.113 117.519 145.086 1.00 245.34 ?  337  PHE A CG  1 
ATOM   1644 C CD1 . PHE A 1 337 ? 128.782 116.478 145.936 1.00 245.34 ?  337  PHE A CD1 1 
ATOM   1645 C CD2 . PHE A 1 337 ? 129.191 117.271 143.729 1.00 245.34 ?  337  PHE A CD2 1 
ATOM   1646 C CE1 . PHE A 1 337 ? 128.527 115.219 145.442 1.00 245.34 ?  337  PHE A CE1 1 
ATOM   1647 C CE2 . PHE A 1 337 ? 128.939 116.012 143.229 1.00 245.34 ?  337  PHE A CE2 1 
ATOM   1648 C CZ  . PHE A 1 337 ? 128.605 114.985 144.087 1.00 245.34 ?  337  PHE A CZ  1 
ATOM   1649 N N   . ARG A 1 338 ? 129.598 120.642 148.589 1.00 255.26 ?  338  ARG A N   1 
ATOM   1650 C CA  . ARG A 1 338 ? 130.079 121.904 149.121 1.00 255.26 ?  338  ARG A CA  1 
ATOM   1651 C C   . ARG A 1 338 ? 131.543 122.029 148.756 1.00 255.26 ?  338  ARG A C   1 
ATOM   1652 O O   . ARG A 1 338 ? 132.416 121.712 149.563 1.00 255.26 ?  338  ARG A O   1 
ATOM   1653 C CB  . ARG A 1 338 ? 129.897 121.945 150.636 1.00 255.26 ?  338  ARG A CB  1 
ATOM   1654 C CG  . ARG A 1 338 ? 128.699 121.153 151.135 1.00 255.26 ?  338  ARG A CG  1 
ATOM   1655 C CD  . ARG A 1 338 ? 129.126 120.022 152.058 1.00 255.26 ?  338  ARG A CD  1 
ATOM   1656 N NE  . ARG A 1 338 ? 129.132 118.729 151.380 1.00 255.26 ?  338  ARG A NE  1 
ATOM   1657 C CZ  . ARG A 1 338 ? 130.230 118.112 150.957 1.00 255.26 ?  338  ARG A CZ  1 
ATOM   1658 N NH1 . ARG A 1 338 ? 130.141 116.938 150.353 1.00 255.26 1  338  ARG A NH1 1 
ATOM   1659 N NH2 . ARG A 1 338 ? 131.420 118.668 151.138 1.00 255.26 ?  338  ARG A NH2 1 
ATOM   1660 N N   . MET A 1 339 ? 131.821 122.479 147.539 1.00 275.55 ?  339  MET A N   1 
ATOM   1661 C CA  . MET A 1 339 ? 133.201 122.564 147.082 1.00 275.55 ?  339  MET A CA  1 
ATOM   1662 C C   . MET A 1 339 ? 133.757 123.978 147.155 1.00 275.55 ?  339  MET A C   1 
ATOM   1663 O O   . MET A 1 339 ? 133.014 124.949 147.018 1.00 275.55 ?  339  MET A O   1 
ATOM   1664 C CB  . MET A 1 339 ? 133.312 122.024 145.657 1.00 275.55 ?  339  MET A CB  1 
ATOM   1665 C CG  . MET A 1 339 ? 133.473 120.516 145.583 1.00 275.55 ?  339  MET A CG  1 
ATOM   1666 S SD  . MET A 1 339 ? 133.020 119.854 143.970 1.00 275.55 ?  339  MET A SD  1 
ATOM   1667 C CE  . MET A 1 339 ? 132.171 121.260 143.257 1.00 275.55 ?  339  MET A CE  1 
ATOM   1668 N N   . ASP A 1 340 ? 135.063 124.097 147.372 1.00 278.57 ?  340  ASP A N   1 
ATOM   1669 C CA  . ASP A 1 340 ? 135.695 125.412 147.434 1.00 278.57 ?  340  ASP A CA  1 
ATOM   1670 C C   . ASP A 1 340 ? 135.929 125.937 146.030 1.00 278.57 ?  340  ASP A C   1 
ATOM   1671 O O   . ASP A 1 340 ? 136.456 125.219 145.184 1.00 278.57 ?  340  ASP A O   1 
ATOM   1672 C CB  . ASP A 1 340 ? 137.013 125.337 148.203 1.00 278.57 ?  340  ASP A CB  1 
ATOM   1673 C CG  . ASP A 1 340 ? 137.505 126.696 148.650 1.00 278.57 ?  340  ASP A CG  1 
ATOM   1674 O OD1 . ASP A 1 340 ? 136.665 127.598 148.851 1.00 278.57 ?  340  ASP A OD1 1 
ATOM   1675 O OD2 . ASP A 1 340 ? 138.733 126.862 148.798 1.00 278.57 -1 340  ASP A OD2 1 
ATOM   1676 N N   . PHE A 1 341 ? 135.555 127.187 145.780 1.00 303.84 ?  341  PHE A N   1 
ATOM   1677 C CA  . PHE A 1 341 ? 135.674 127.762 144.434 1.00 303.84 ?  341  PHE A CA  1 
ATOM   1678 C C   . PHE A 1 341 ? 137.007 127.596 143.690 1.00 303.84 ?  341  PHE A C   1 
ATOM   1679 O O   . PHE A 1 341 ? 137.009 127.117 142.555 1.00 303.84 ?  341  PHE A O   1 
ATOM   1680 C CB  . PHE A 1 341 ? 135.221 129.236 144.431 1.00 303.84 ?  341  PHE A CB  1 
ATOM   1681 C CG  . PHE A 1 341 ? 135.657 130.009 143.217 1.00 303.84 ?  341  PHE A CG  1 
ATOM   1682 C CD1 . PHE A 1 341 ? 135.077 129.773 141.980 1.00 303.84 ?  341  PHE A CD1 1 
ATOM   1683 C CD2 . PHE A 1 341 ? 136.642 130.980 143.314 1.00 303.84 ?  341  PHE A CD2 1 
ATOM   1684 C CE1 . PHE A 1 341 ? 135.480 130.480 140.864 1.00 303.84 ?  341  PHE A CE1 1 
ATOM   1685 C CE2 . PHE A 1 341 ? 137.049 131.690 142.201 1.00 303.84 ?  341  PHE A CE2 1 
ATOM   1686 C CZ  . PHE A 1 341 ? 136.465 131.441 140.975 1.00 303.84 ?  341  PHE A CZ  1 
ATOM   1687 N N   . PRO A 1 342 ? 138.144 127.986 144.304 1.00 254.20 ?  342  PRO A N   1 
ATOM   1688 C CA  . PRO A 1 342 ? 139.385 127.910 143.516 1.00 254.20 ?  342  PRO A CA  1 
ATOM   1689 C C   . PRO A 1 342 ? 139.674 126.550 142.885 1.00 254.20 ?  342  PRO A C   1 
ATOM   1690 O O   . PRO A 1 342 ? 140.257 126.552 141.803 1.00 254.20 ?  342  PRO A O   1 
ATOM   1691 C CB  . PRO A 1 342 ? 140.468 128.278 144.531 1.00 254.20 ?  342  PRO A CB  1 
ATOM   1692 C CG  . PRO A 1 342 ? 139.767 129.121 145.535 1.00 254.20 ?  342  PRO A CG  1 
ATOM   1693 C CD  . PRO A 1 342 ? 138.398 128.524 145.654 1.00 254.20 ?  342  PRO A CD  1 
ATOM   1694 N N   . PHE A 1 343 ? 139.299 125.446 143.531 1.00 275.51 ?  343  PHE A N   1 
ATOM   1695 C CA  . PHE A 1 343 ? 139.515 124.083 143.004 1.00 275.51 ?  343  PHE A CA  1 
ATOM   1696 C C   . PHE A 1 343 ? 140.968 123.596 143.019 1.00 275.51 ?  343  PHE A C   1 
ATOM   1697 O O   . PHE A 1 343 ? 141.885 124.305 142.606 1.00 275.51 ?  343  PHE A O   1 
ATOM   1698 C CB  . PHE A 1 343 ? 138.780 123.851 141.658 1.00 275.51 ?  343  PHE A CB  1 
ATOM   1699 C CG  . PHE A 1 343 ? 139.654 123.350 140.536 1.00 275.51 ?  343  PHE A CG  1 
ATOM   1700 C CD1 . PHE A 1 343 ? 139.916 121.997 140.385 1.00 275.51 ?  343  PHE A CD1 1 
ATOM   1701 C CD2 . PHE A 1 343 ? 140.169 124.230 139.599 1.00 275.51 ?  343  PHE A CD2 1 
ATOM   1702 C CE1 . PHE A 1 343 ? 140.710 121.541 139.350 1.00 275.51 ?  343  PHE A CE1 1 
ATOM   1703 C CE2 . PHE A 1 343 ? 140.958 123.780 138.560 1.00 275.51 ?  343  PHE A CE2 1 
ATOM   1704 C CZ  . PHE A 1 343 ? 141.228 122.434 138.435 1.00 275.51 ?  343  PHE A CZ  1 
ATOM   1705 N N   . ASP A 1 344 ? 141.175 122.380 143.510 1.00 271.16 ?  344  ASP A N   1 
ATOM   1706 C CA  . ASP A 1 344 ? 142.524 121.836 143.609 1.00 271.16 ?  344  ASP A CA  1 
ATOM   1707 C C   . ASP A 1 344 ? 143.098 121.468 142.261 1.00 271.16 ?  344  ASP A C   1 
ATOM   1708 O O   . ASP A 1 344 ? 142.653 120.510 141.639 1.00 271.16 ?  344  ASP A O   1 
ATOM   1709 C CB  . ASP A 1 344 ? 142.500 120.594 144.493 1.00 271.16 ?  344  ASP A CB  1 
ATOM   1710 C CG  . ASP A 1 344 ? 143.876 120.159 144.931 1.00 271.16 ?  344  ASP A CG  1 
ATOM   1711 O OD1 . ASP A 1 344 ? 144.732 121.031 145.169 1.00 271.16 ?  344  ASP A OD1 1 
ATOM   1712 O OD2 . ASP A 1 344 ? 144.100 118.939 145.040 1.00 271.16 -1 344  ASP A OD2 1 
ATOM   1713 N N   . LEU A 1 345 ? 144.111 122.198 141.814 1.00 247.04 ?  345  LEU A N   1 
ATOM   1714 C CA  . LEU A 1 345 ? 144.758 121.854 140.557 1.00 247.04 ?  345  LEU A CA  1 
ATOM   1715 C C   . LEU A 1 345 ? 145.695 120.678 140.745 1.00 247.04 ?  345  LEU A C   1 
ATOM   1716 O O   . LEU A 1 345 ? 146.252 120.170 139.778 1.00 247.04 ?  345  LEU A O   1 
ATOM   1717 C CB  . LEU A 1 345 ? 145.514 123.046 139.977 1.00 247.04 ?  345  LEU A CB  1 
ATOM   1718 C CG  . LEU A 1 345 ? 144.799 123.843 138.889 1.00 247.04 ?  345  LEU A CG  1 
ATOM   1719 C CD1 . LEU A 1 345 ? 144.417 125.222 139.404 1.00 247.04 ?  345  LEU A CD1 1 
ATOM   1720 C CD2 . LEU A 1 345 ? 145.676 123.953 137.653 1.00 247.04 ?  345  LEU A CD2 1 
ATOM   1721 N N   . LYS A 1 346 ? 145.880 120.241 141.985 1.00 266.65 ?  346  LYS A N   1 
ATOM   1722 C CA  . LYS A 1 346 ? 146.711 119.076 142.238 1.00 266.65 ?  346  LYS A CA  1 
ATOM   1723 C C   . LYS A 1 346 ? 145.913 117.817 141.960 1.00 266.65 ?  346  LYS A C   1 
ATOM   1724 O O   . LYS A 1 346 ? 146.488 116.761 141.711 1.00 266.65 ?  346  LYS A O   1 
ATOM   1725 C CB  . LYS A 1 346 ? 147.226 119.073 143.673 1.00 266.65 ?  346  LYS A CB  1 
ATOM   1726 C CG  . LYS A 1 346 ? 148.253 120.154 143.959 1.00 266.65 ?  346  LYS A CG  1 
ATOM   1727 C CD  . LYS A 1 346 ? 149.180 119.749 145.092 1.00 266.65 ?  346  LYS A CD  1 
ATOM   1728 C CE  . LYS A 1 346 ? 148.902 118.327 145.550 1.00 266.65 ?  346  LYS A CE  1 
ATOM   1729 N NZ  . LYS A 1 346 ? 149.421 118.078 146.923 1.00 266.65 1  346  LYS A NZ  1 
ATOM   1730 N N   . GLU A 1 347 ? 144.588 117.920 141.998 1.00 288.93 ?  347  GLU A N   1 
ATOM   1731 C CA  . GLU A 1 347 ? 143.755 116.769 141.666 1.00 288.93 ?  347  GLU A CA  1 
ATOM   1732 C C   . GLU A 1 347 ? 143.232 116.871 140.247 1.00 288.93 ?  347  GLU A C   1 
ATOM   1733 O O   . GLU A 1 347 ? 142.479 116.013 139.802 1.00 288.93 ?  347  GLU A O   1 
ATOM   1734 C CB  . GLU A 1 347 ? 142.635 116.552 142.689 1.00 288.93 ?  347  GLU A CB  1 
ATOM   1735 C CG  . GLU A 1 347 ? 141.503 117.558 142.676 1.00 288.93 ?  347  GLU A CG  1 
ATOM   1736 C CD  . GLU A 1 347 ? 140.538 117.335 143.825 1.00 288.93 ?  347  GLU A CD  1 
ATOM   1737 O OE1 . GLU A 1 347 ? 140.941 117.531 144.991 1.00 288.93 ?  347  GLU A OE1 1 
ATOM   1738 O OE2 . GLU A 1 347 ? 139.378 116.953 143.566 1.00 288.93 -1 347  GLU A OE2 1 
ATOM   1739 N N   . LEU A 1 348 ? 143.632 117.910 139.525 1.00 269.76 ?  348  LEU A N   1 
ATOM   1740 C CA  . LEU A 1 348 ? 143.259 118.012 138.114 1.00 269.76 ?  348  LEU A CA  1 
ATOM   1741 C C   . LEU A 1 348 ? 143.855 116.875 137.282 1.00 269.76 ?  348  LEU A C   1 
ATOM   1742 O O   . LEU A 1 348 ? 143.193 116.371 136.384 1.00 269.76 ?  348  LEU A O   1 
ATOM   1743 C CB  . LEU A 1 348 ? 143.629 119.379 137.528 1.00 269.76 ?  348  LEU A CB  1 
ATOM   1744 C CG  . LEU A 1 348 ? 143.199 119.666 136.086 1.00 269.76 ?  348  LEU A CG  1 
ATOM   1745 C CD1 . LEU A 1 348 ? 141.688 119.592 135.936 1.00 269.76 ?  348  LEU A CD1 1 
ATOM   1746 C CD2 . LEU A 1 348 ? 143.722 121.016 135.625 1.00 269.76 ?  348  LEU A CD2 1 
ATOM   1747 N N   . PRO A 1 349 ? 145.114 116.470 137.555 1.00 289.85 ?  349  PRO A N   1 
ATOM   1748 C CA  . PRO A 1 349 ? 145.606 115.302 136.815 1.00 289.85 ?  349  PRO A CA  1 
ATOM   1749 C C   . PRO A 1 349 ? 144.673 114.094 136.909 1.00 289.85 ?  349  PRO A C   1 
ATOM   1750 O O   . PRO A 1 349 ? 144.554 113.360 135.936 1.00 289.85 ?  349  PRO A O   1 
ATOM   1751 C CB  . PRO A 1 349 ? 146.922 114.994 137.517 1.00 289.85 ?  349  PRO A CB  1 
ATOM   1752 C CG  . PRO A 1 349 ? 147.433 116.328 137.916 1.00 289.85 ?  349  PRO A CG  1 
ATOM   1753 C CD  . PRO A 1 349 ? 146.236 117.196 138.186 1.00 289.85 ?  349  PRO A CD  1 
ATOM   1754 N N   . ALA A 1 350 ? 144.030 113.888 138.054 1.00 309.05 ?  350  ALA A N   1 
ATOM   1755 C CA  . ALA A 1 350 ? 143.104 112.775 138.216 1.00 309.05 ?  350  ALA A CA  1 
ATOM   1756 C C   . ALA A 1 350 ? 141.885 112.940 137.334 1.00 309.05 ?  350  ALA A C   1 
ATOM   1757 O O   . ALA A 1 350 ? 141.440 111.984 136.714 1.00 309.05 ?  350  ALA A O   1 
ATOM   1758 C CB  . ALA A 1 350 ? 142.688 112.641 139.665 1.00 309.05 ?  350  ALA A CB  1 
ATOM   1759 N N   . PHE A 1 351 ? 141.340 114.147 137.272 1.00 310.03 ?  351  PHE A N   1 
ATOM   1760 C CA  . PHE A 1 351 ? 140.196 114.408 136.407 1.00 310.03 ?  351  PHE A CA  1 
ATOM   1761 C C   . PHE A 1 351 ? 140.572 114.218 134.949 1.00 310.03 ?  351  PHE A C   1 
ATOM   1762 O O   . PHE A 1 351 ? 139.775 113.724 134.159 1.00 310.03 ?  351  PHE A O   1 
ATOM   1763 C CB  . PHE A 1 351 ? 139.673 115.821 136.630 1.00 310.03 ?  351  PHE A CB  1 
ATOM   1764 C CG  . PHE A 1 351 ? 139.028 116.021 137.967 1.00 310.03 ?  351  PHE A CG  1 
ATOM   1765 C CD1 . PHE A 1 351 ? 137.929 115.269 138.338 1.00 310.03 ?  351  PHE A CD1 1 
ATOM   1766 C CD2 . PHE A 1 351 ? 139.519 116.962 138.852 1.00 310.03 ?  351  PHE A CD2 1 
ATOM   1767 C CE1 . PHE A 1 351 ? 137.330 115.454 139.567 1.00 310.03 ?  351  PHE A CE1 1 
ATOM   1768 C CE2 . PHE A 1 351 ? 138.926 117.150 140.083 1.00 310.03 ?  351  PHE A CE2 1 
ATOM   1769 C CZ  . PHE A 1 351 ? 137.830 116.394 140.442 1.00 310.03 ?  351  PHE A CZ  1 
ATOM   1770 N N   . ALA A 1 352 ? 141.788 114.601 134.586 1.00 330.93 ?  352  ALA A N   1 
ATOM   1771 C CA  . ALA A 1 352 ? 142.249 114.419 133.218 1.00 330.93 ?  352  ALA A CA  1 
ATOM   1772 C C   . ALA A 1 352 ? 142.426 112.945 132.919 1.00 330.93 ?  352  ALA A C   1 
ATOM   1773 O O   . ALA A 1 352 ? 142.120 112.499 131.823 1.00 330.93 ?  352  ALA A O   1 
ATOM   1774 C CB  . ALA A 1 352 ? 143.551 115.162 132.998 1.00 330.93 ?  352  ALA A CB  1 
ATOM   1775 N N   . ALA A 1 353 ? 142.918 112.184 133.889 1.00 337.56 ?  353  ALA A N   1 
ATOM   1776 C CA  . ALA A 1 353 ? 143.073 110.746 133.707 1.00 337.56 ?  353  ALA A CA  1 
ATOM   1777 C C   . ALA A 1 353 ? 141.714 110.109 133.530 1.00 337.56 ?  353  ALA A C   1 
ATOM   1778 O O   . ALA A 1 353 ? 141.560 109.212 132.710 1.00 337.56 ?  353  ALA A O   1 
ATOM   1779 C CB  . ALA A 1 353 ? 143.797 110.131 134.887 1.00 337.56 ?  353  ALA A CB  1 
ATOM   1780 N N   . ILE A 1 354 ? 140.722 110.563 134.290 1.00 316.46 ?  354  ILE A N   1 
ATOM   1781 C CA  . ILE A 1 354 ? 139.368 110.061 134.112 1.00 316.46 ?  354  ILE A CA  1 
ATOM   1782 C C   . ILE A 1 354 ? 139.004 110.267 132.659 1.00 316.46 ?  354  ILE A C   1 
ATOM   1783 O O   . ILE A 1 354 ? 138.619 109.328 131.985 1.00 316.46 ?  354  ILE A O   1 
ATOM   1784 C CB  . ILE A 1 354 ? 138.354 110.803 135.000 1.00 316.46 ?  354  ILE A CB  1 
ATOM   1785 C CG1 . ILE A 1 354 ? 138.515 110.400 136.462 1.00 316.46 ?  354  ILE A CG1 1 
ATOM   1786 C CG2 . ILE A 1 354 ? 136.931 110.518 134.555 1.00 316.46 ?  354  ILE A CG2 1 
ATOM   1787 C CD1 . ILE A 1 354 ? 137.482 111.029 137.367 1.00 316.46 ?  354  ILE A CD1 1 
ATOM   1788 N N   . GLY A 1 355 ? 139.160 111.487 132.162 1.00 313.43 ?  355  GLY A N   1 
ATOM   1789 C CA  . GLY A 1 355 ? 138.864 111.777 130.774 1.00 313.43 ?  355  GLY A CA  1 
ATOM   1790 C C   . GLY A 1 355 ? 139.544 110.863 129.782 1.00 313.43 ?  355  GLY A C   1 
ATOM   1791 O O   . GLY A 1 355 ? 138.889 110.287 128.927 1.00 313.43 ?  355  GLY A O   1 
ATOM   1792 N N   . ILE A 1 356 ? 140.857 110.724 129.884 1.00 339.55 ?  356  ILE A N   1 
ATOM   1793 C CA  . ILE A 1 356 ? 141.596 109.883 128.955 1.00 339.55 ?  356  ILE A CA  1 
ATOM   1794 C C   . ILE A 1 356 ? 141.060 108.463 128.972 1.00 339.55 ?  356  ILE A C   1 
ATOM   1795 O O   . ILE A 1 356 ? 140.761 107.894 127.925 1.00 339.55 ?  356  ILE A O   1 
ATOM   1796 C CB  . ILE A 1 356 ? 143.100 109.867 129.284 1.00 339.55 ?  356  ILE A CB  1 
ATOM   1797 C CG1 . ILE A 1 356 ? 143.681 111.275 129.184 1.00 339.55 ?  356  ILE A CG1 1 
ATOM   1798 C CG2 . ILE A 1 356 ? 143.852 108.929 128.352 1.00 339.55 ?  356  ILE A CG2 1 
ATOM   1799 C CD1 . ILE A 1 356 ? 144.288 111.589 127.836 1.00 339.55 ?  356  ILE A CD1 1 
ATOM   1800 N N   . CYS A 1 357 ? 140.919 107.891 130.161 1.00 342.37 ?  357  CYS A N   1 
ATOM   1801 C CA  . CYS A 1 357 ? 140.444 106.520 130.276 1.00 342.37 ?  357  CYS A CA  1 
ATOM   1802 C C   . CYS A 1 357 ? 139.000 106.382 129.842 1.00 342.37 ?  357  CYS A C   1 
ATOM   1803 O O   . CYS A 1 357 ? 138.625 105.366 129.279 1.00 342.37 ?  357  CYS A O   1 
ATOM   1804 C CB  . CYS A 1 357 ? 140.623 106.015 131.701 1.00 342.37 ?  357  CYS A CB  1 
ATOM   1805 S SG  . CYS A 1 357 ? 142.337 105.950 132.264 1.00 342.37 ?  357  CYS A SG  1 
ATOM   1806 N N   . CYS A 1 358 ? 138.188 107.401 130.084 1.00 330.10 ?  358  CYS A N   1 
ATOM   1807 C CA  . CYS A 1 358 ? 136.799 107.375 129.651 1.00 330.10 ?  358  CYS A CA  1 
ATOM   1808 C C   . CYS A 1 358 ? 136.719 107.452 128.141 1.00 330.10 ?  358  CYS A C   1 
ATOM   1809 O O   . CYS A 1 358 ? 135.789 106.926 127.547 1.00 330.10 ?  358  CYS A O   1 
ATOM   1810 C CB  . CYS A 1 358 ? 136.014 108.520 130.278 1.00 330.10 ?  358  CYS A CB  1 
ATOM   1811 S SG  . CYS A 1 358 ? 135.413 108.188 131.948 1.00 330.10 ?  358  CYS A SG  1 
ATOM   1812 N N   . GLY A 1 359 ? 137.690 108.101 127.512 1.00 335.59 ?  359  GLY A N   1 
ATOM   1813 C CA  . GLY A 1 359 ? 137.725 108.161 126.064 1.00 335.59 ?  359  GLY A CA  1 
ATOM   1814 C C   . GLY A 1 359 ? 138.065 106.804 125.507 1.00 335.59 ?  359  GLY A C   1 
ATOM   1815 O O   . GLY A 1 359 ? 137.486 106.372 124.516 1.00 335.59 ?  359  GLY A O   1 
ATOM   1816 N N   . LEU A 1 360 ? 138.999 106.117 126.149 1.00 355.91 ?  360  LEU A N   1 
ATOM   1817 C CA  . LEU A 1 360 ? 139.361 104.779 125.717 1.00 355.91 ?  360  LEU A CA  1 
ATOM   1818 C C   . LEU A 1 360 ? 138.187 103.845 125.907 1.00 355.91 ?  360  LEU A C   1 
ATOM   1819 O O   . LEU A 1 360 ? 137.878 103.052 125.028 1.00 355.91 ?  360  LEU A O   1 
ATOM   1820 C CB  . LEU A 1 360 ? 140.557 104.266 126.515 1.00 355.91 ?  360  LEU A CB  1 
ATOM   1821 C CG  . LEU A 1 360 ? 141.914 104.923 126.273 1.00 355.91 ?  360  LEU A CG  1 
ATOM   1822 C CD1 . LEU A 1 360 ? 142.744 104.906 127.546 1.00 355.91 ?  360  LEU A CD1 1 
ATOM   1823 C CD2 . LEU A 1 360 ? 142.648 104.211 125.150 1.00 355.91 ?  360  LEU A CD2 1 
ATOM   1824 N N   . LEU A 1 361 ? 137.519 103.944 127.050 1.00 288.30 ?  361  LEU A N   1 
ATOM   1825 C CA  . LEU A 1 361 ? 136.390 103.069 127.339 1.00 288.30 ?  361  LEU A CA  1 
ATOM   1826 C C   . LEU A 1 361 ? 135.188 103.413 126.486 1.00 288.30 ?  361  LEU A C   1 
ATOM   1827 O O   . LEU A 1 361 ? 134.380 102.548 126.181 1.00 288.30 ?  361  LEU A O   1 
ATOM   1828 C CB  . LEU A 1 361 ? 136.030 103.138 128.820 1.00 288.30 ?  361  LEU A CB  1 
ATOM   1829 C CG  . LEU A 1 361 ? 137.034 102.469 129.754 1.00 288.30 ?  361  LEU A CG  1 
ATOM   1830 C CD1 . LEU A 1 361 ? 136.950 103.060 131.152 1.00 288.30 ?  361  LEU A CD1 1 
ATOM   1831 C CD2 . LEU A 1 361 ? 136.830 100.964 129.776 1.00 288.30 ?  361  LEU A CD2 1 
ATOM   1832 N N   . GLY A 1 362 ? 135.065 104.671 126.091 1.00 272.11 ?  362  GLY A N   1 
ATOM   1833 C CA  . GLY A 1 362 ? 133.975 105.072 125.228 1.00 272.11 ?  362  GLY A CA  1 
ATOM   1834 C C   . GLY A 1 362 ? 134.167 104.453 123.873 1.00 272.11 ?  362  GLY A C   1 
ATOM   1835 O O   . GLY A 1 362 ? 133.213 103.999 123.256 1.00 272.11 ?  362  GLY A O   1 
ATOM   1836 N N   . ALA A 1 363 ? 135.407 104.415 123.407 1.00 285.87 ?  363  ALA A N   1 
ATOM   1837 C CA  . ALA A 1 363 ? 135.696 103.791 122.131 1.00 285.87 ?  363  ALA A CA  1 
ATOM   1838 C C   . ALA A 1 363 ? 135.453 102.298 122.209 1.00 285.87 ?  363  ALA A C   1 
ATOM   1839 O O   . ALA A 1 363 ? 134.922 101.715 121.276 1.00 285.87 ?  363  ALA A O   1 
ATOM   1840 C CB  . ALA A 1 363 ? 137.121 104.077 121.719 1.00 285.87 ?  363  ALA A CB  1 
ATOM   1841 N N   . VAL A 1 364 ? 135.824 101.673 123.319 1.00 252.87 ?  364  VAL A N   1 
ATOM   1842 C CA  . VAL A 1 364 ? 135.566 100.247 123.494 1.00 252.87 ?  364  VAL A CA  1 
ATOM   1843 C C   . VAL A 1 364 ? 134.068 99.986  123.471 1.00 252.87 ?  364  VAL A C   1 
ATOM   1844 O O   . VAL A 1 364 ? 133.616 99.046  122.832 1.00 252.87 ?  364  VAL A O   1 
ATOM   1845 C CB  . VAL A 1 364 ? 136.194 99.710  124.795 1.00 252.87 ?  364  VAL A CB  1 
ATOM   1846 C CG1 . VAL A 1 364 ? 135.755 98.282  125.067 1.00 252.87 ?  364  VAL A CG1 1 
ATOM   1847 C CG2 . VAL A 1 364 ? 137.709 99.778  124.714 1.00 252.87 ?  364  VAL A CG2 1 
ATOM   1848 N N   . PHE A 1 365 ? 133.289 100.826 124.143 1.00 248.26 ?  365  PHE A N   1 
ATOM   1849 C CA  . PHE A 1 365 ? 131.841 100.680 124.125 1.00 248.26 ?  365  PHE A CA  1 
ATOM   1850 C C   . PHE A 1 365 ? 131.343 100.707 122.696 1.00 248.26 ?  365  PHE A C   1 
ATOM   1851 O O   . PHE A 1 365 ? 130.672 99.783  122.261 1.00 248.26 ?  365  PHE A O   1 
ATOM   1852 C CB  . PHE A 1 365 ? 131.176 101.797 124.929 1.00 248.26 ?  365  PHE A CB  1 
ATOM   1853 C CG  . PHE A 1 365 ? 129.729 101.545 125.249 1.00 248.26 ?  365  PHE A CG  1 
ATOM   1854 C CD1 . PHE A 1 365 ? 128.732 101.883 124.348 1.00 248.26 ?  365  PHE A CD1 1 
ATOM   1855 C CD2 . PHE A 1 365 ? 129.366 100.983 126.459 1.00 248.26 ?  365  PHE A CD2 1 
ATOM   1856 C CE1 . PHE A 1 365 ? 127.403 101.652 124.641 1.00 248.26 ?  365  PHE A CE1 1 
ATOM   1857 C CE2 . PHE A 1 365 ? 128.039 100.752 126.759 1.00 248.26 ?  365  PHE A CE2 1 
ATOM   1858 C CZ  . PHE A 1 365 ? 127.056 101.087 125.850 1.00 248.26 ?  365  PHE A CZ  1 
ATOM   1859 N N   . VAL A 1 366 ? 131.668 101.765 121.963 1.00 255.93 ?  366  VAL A N   1 
ATOM   1860 C CA  . VAL A 1 366 ? 131.203 101.891 120.589 1.00 255.93 ?  366  VAL A CA  1 
ATOM   1861 C C   . VAL A 1 366 ? 131.642 100.694 119.763 1.00 255.93 ?  366  VAL A C   1 
ATOM   1862 O O   . VAL A 1 366 ? 130.829 100.086 119.073 1.00 255.93 ?  366  VAL A O   1 
ATOM   1863 C CB  . VAL A 1 366 ? 131.688 103.195 119.934 1.00 255.93 ?  366  VAL A CB  1 
ATOM   1864 C CG1 . VAL A 1 366 ? 131.230 103.262 118.490 1.00 255.93 ?  366  VAL A CG1 1 
ATOM   1865 C CG2 . VAL A 1 366 ? 131.168 104.397 120.703 1.00 255.93 ?  366  VAL A CG2 1 
ATOM   1866 N N   . TYR A 1 367 ? 132.916 100.336 119.849 1.00 277.07 ?  367  TYR A N   1 
ATOM   1867 C CA  . TYR A 1 367 ? 133.424 99.196  119.103 1.00 277.07 ?  367  TYR A CA  1 
ATOM   1868 C C   . TYR A 1 367 ? 132.656 97.934  119.416 1.00 277.07 ?  367  TYR A C   1 
ATOM   1869 O O   . TYR A 1 367 ? 132.148 97.282  118.516 1.00 277.07 ?  367  TYR A O   1 
ATOM   1870 C CB  . TYR A 1 367 ? 134.898 98.973  119.415 1.00 277.07 ?  367  TYR A CB  1 
ATOM   1871 C CG  . TYR A 1 367 ? 135.537 97.879  118.597 1.00 277.07 ?  367  TYR A CG  1 
ATOM   1872 C CD1 . TYR A 1 367 ? 135.860 98.084  117.265 1.00 277.07 ?  367  TYR A CD1 1 
ATOM   1873 C CD2 . TYR A 1 367 ? 135.819 96.642  119.156 1.00 277.07 ?  367  TYR A CD2 1 
ATOM   1874 C CE1 . TYR A 1 367 ? 136.445 97.088  116.512 1.00 277.07 ?  367  TYR A CE1 1 
ATOM   1875 C CE2 . TYR A 1 367 ? 136.401 95.638  118.411 1.00 277.07 ?  367  TYR A CE2 1 
ATOM   1876 C CZ  . TYR A 1 367 ? 136.712 95.867  117.089 1.00 277.07 ?  367  TYR A CZ  1 
ATOM   1877 O OH  . TYR A 1 367 ? 137.294 94.870  116.342 1.00 277.07 ?  367  TYR A OH  1 
ATOM   1878 N N   . LEU A 1 368 ? 132.567 97.581  120.689 1.00 258.19 ?  368  LEU A N   1 
ATOM   1879 C CA  . LEU A 1 368 ? 131.904 96.345  121.077 1.00 258.19 ?  368  LEU A CA  1 
ATOM   1880 C C   . LEU A 1 368 ? 130.427 96.342  120.734 1.00 258.19 ?  368  LEU A C   1 
ATOM   1881 O O   . LEU A 1 368 ? 129.886 95.315  120.344 1.00 258.19 ?  368  LEU A O   1 
ATOM   1882 C CB  . LEU A 1 368 ? 132.099 96.090  122.566 1.00 258.19 ?  368  LEU A CB  1 
ATOM   1883 C CG  . LEU A 1 368 ? 132.988 94.914  122.963 1.00 258.19 ?  368  LEU A CG  1 
ATOM   1884 C CD1 . LEU A 1 368 ? 134.043 94.638  121.904 1.00 258.19 ?  368  LEU A CD1 1 
ATOM   1885 C CD2 . LEU A 1 368 ? 133.634 95.175  124.313 1.00 258.19 ?  368  LEU A CD2 1 
ATOM   1886 N N   . HIS A 1 369 ? 129.770 97.484  120.874 1.00 221.21 ?  369  HIS A N   1 
ATOM   1887 C CA  . HIS A 1 369 ? 128.365 97.573  120.522 1.00 221.21 ?  369  HIS A CA  1 
ATOM   1888 C C   . HIS A 1 369 ? 128.191 97.362  119.033 1.00 221.21 ?  369  HIS A C   1 
ATOM   1889 O O   . HIS A 1 369 ? 127.304 96.634  118.615 1.00 221.21 ?  369  HIS A O   1 
ATOM   1890 C CB  . HIS A 1 369 ? 127.776 98.917  120.938 1.00 221.21 ?  369  HIS A CB  1 
ATOM   1891 C CG  . HIS A 1 369 ? 126.390 99.149  120.428 1.00 221.21 ?  369  HIS A CG  1 
ATOM   1892 N ND1 . HIS A 1 369 ? 125.314 98.387  120.827 1.00 221.21 ?  369  HIS A ND1 1 
ATOM   1893 C CD2 . HIS A 1 369 ? 125.905 100.051 119.543 1.00 221.21 ?  369  HIS A CD2 1 
ATOM   1894 C CE1 . HIS A 1 369 ? 124.226 98.812  120.212 1.00 221.21 ?  369  HIS A CE1 1 
ATOM   1895 N NE2 . HIS A 1 369 ? 124.556 99.822  119.429 1.00 221.21 ?  369  HIS A NE2 1 
ATOM   1896 N N   . ARG A 1 370 ? 129.039 97.987  118.225 1.00 225.90 ?  370  ARG A N   1 
ATOM   1897 C CA  . ARG A 1 370 ? 128.970 97.805  116.780 1.00 225.90 ?  370  ARG A CA  1 
ATOM   1898 C C   . ARG A 1 370 ? 129.262 96.367  116.419 1.00 225.90 ?  370  ARG A C   1 
ATOM   1899 O O   . ARG A 1 370 ? 128.623 95.803  115.545 1.00 225.90 ?  370  ARG A O   1 
ATOM   1900 C CB  . ARG A 1 370 ? 129.961 98.727  116.079 1.00 225.90 ?  370  ARG A CB  1 
ATOM   1901 C CG  . ARG A 1 370 ? 130.026 98.564  114.570 1.00 225.90 ?  370  ARG A CG  1 
ATOM   1902 C CD  . ARG A 1 370 ? 131.099 99.450  113.966 1.00 225.90 ?  370  ARG A CD  1 
ATOM   1903 N NE  . ARG A 1 370 ? 131.584 100.435 114.924 1.00 225.90 ?  370  ARG A NE  1 
ATOM   1904 C CZ  . ARG A 1 370 ? 132.840 100.510 115.348 1.00 225.90 ?  370  ARG A CZ  1 
ATOM   1905 N NH1 . ARG A 1 370 ? 133.745 99.652  114.901 1.00 225.90 1  370  ARG A NH1 1 
ATOM   1906 N NH2 . ARG A 1 370 ? 133.186 101.439 116.224 1.00 225.90 ?  370  ARG A NH2 1 
ATOM   1907 N N   . GLN A 1 371 ? 130.218 95.761  117.105 1.00 244.03 ?  371  GLN A N   1 
ATOM   1908 C CA  . GLN A 1 371 ? 130.585 94.385  116.819 1.00 244.03 ?  371  GLN A CA  1 
ATOM   1909 C C   . GLN A 1 371 ? 129.442 93.433  117.124 1.00 244.03 ?  371  GLN A C   1 
ATOM   1910 O O   . GLN A 1 371 ? 129.192 92.506  116.365 1.00 244.03 ?  371  GLN A O   1 
ATOM   1911 C CB  . GLN A 1 371 ? 131.837 93.997  117.606 1.00 244.03 ?  371  GLN A CB  1 
ATOM   1912 C CG  . GLN A 1 371 ? 133.115 93.927  116.782 1.00 244.03 ?  371  GLN A CG  1 
ATOM   1913 C CD  . GLN A 1 371 ? 133.186 94.976  115.687 1.00 244.03 ?  371  GLN A CD  1 
ATOM   1914 O OE1 . GLN A 1 371 ? 133.237 96.175  115.959 1.00 244.03 ?  371  GLN A OE1 1 
ATOM   1915 N NE2 . GLN A 1 371 ? 133.204 94.526  114.439 1.00 244.03 ?  371  GLN A NE2 1 
ATOM   1916 N N   . VAL A 1 372 ? 128.744 93.659  118.229 1.00 207.35 ?  372  VAL A N   1 
ATOM   1917 C CA  . VAL A 1 372 ? 127.604 92.820  118.584 1.00 207.35 ?  372  VAL A CA  1 
ATOM   1918 C C   . VAL A 1 372 ? 126.458 93.120  117.639 1.00 207.35 ?  372  VAL A C   1 
ATOM   1919 O O   . VAL A 1 372 ? 125.750 92.213  117.211 1.00 207.35 ?  372  VAL A O   1 
ATOM   1920 C CB  . VAL A 1 372 ? 127.166 93.064  120.044 1.00 207.35 ?  372  VAL A CB  1 
ATOM   1921 C CG1 . VAL A 1 372 ? 125.846 92.376  120.350 1.00 207.35 ?  372  VAL A CG1 1 
ATOM   1922 C CG2 . VAL A 1 372 ? 128.237 92.574  121.005 1.00 207.35 ?  372  VAL A CG2 1 
ATOM   1923 N N   . MET A 1 373 ? 126.297 94.384  117.268 1.00 218.54 ?  373  MET A N   1 
ATOM   1924 C CA  . MET A 1 373 ? 125.174 94.772  116.429 1.00 218.54 ?  373  MET A CA  1 
ATOM   1925 C C   . MET A 1 373 ? 125.348 94.131  115.075 1.00 218.54 ?  373  MET A C   1 
ATOM   1926 O O   . MET A 1 373 ? 124.399 93.614  114.510 1.00 218.54 ?  373  MET A O   1 
ATOM   1927 C CB  . MET A 1 373 ? 125.098 96.289  116.281 1.00 218.54 ?  373  MET A CB  1 
ATOM   1928 C CG  . MET A 1 373 ? 123.754 96.887  116.649 1.00 218.54 ?  373  MET A CG  1 
ATOM   1929 S SD  . MET A 1 373 ? 123.639 98.633  116.219 1.00 218.54 ?  373  MET A SD  1 
ATOM   1930 C CE  . MET A 1 373 ? 121.984 99.011  116.788 1.00 218.54 ?  373  MET A CE  1 
ATOM   1931 N N   . LEU A 1 374 ? 126.567 94.160  114.551 1.00 247.46 ?  374  LEU A N   1 
ATOM   1932 C CA  . LEU A 1 374 ? 126.836 93.537  113.269 1.00 247.46 ?  374  LEU A CA  1 
ATOM   1933 C C   . LEU A 1 374 ? 126.727 92.043  113.431 1.00 247.46 ?  374  LEU A C   1 
ATOM   1934 O O   . LEU A 1 374 ? 126.000 91.398  112.693 1.00 247.46 ?  374  LEU A O   1 
ATOM   1935 C CB  . LEU A 1 374 ? 128.228 93.905  112.770 1.00 247.46 ?  374  LEU A CB  1 
ATOM   1936 C CG  . LEU A 1 374 ? 128.392 95.303  112.177 1.00 247.46 ?  374  LEU A CG  1 
ATOM   1937 C CD1 . LEU A 1 374 ? 129.865 95.615  111.969 1.00 247.46 ?  374  LEU A CD1 1 
ATOM   1938 C CD2 . LEU A 1 374 ? 127.623 95.426  110.873 1.00 247.46 ?  374  LEU A CD2 1 
ATOM   1939 N N   . GLY A 1 375 ? 127.428 91.491  114.410 1.00 229.17 ?  375  GLY A N   1 
ATOM   1940 C CA  . GLY A 1 375 ? 127.410 90.058  114.641 1.00 229.17 ?  375  GLY A CA  1 
ATOM   1941 C C   . GLY A 1 375 ? 126.061 89.377  114.581 1.00 229.17 ?  375  GLY A C   1 
ATOM   1942 O O   . GLY A 1 375 ? 125.920 88.357  113.913 1.00 229.17 ?  375  GLY A O   1 
ATOM   1943 N N   . VAL A 1 376 ? 125.063 89.925  115.266 1.00 228.87 ?  376  VAL A N   1 
ATOM   1944 C CA  . VAL A 1 376 ? 123.757 89.269  115.314 1.00 228.87 ?  376  VAL A CA  1 
ATOM   1945 C C   . VAL A 1 376 ? 123.068 89.178  113.954 1.00 228.87 ?  376  VAL A C   1 
ATOM   1946 O O   . VAL A 1 376 ? 122.241 88.293  113.745 1.00 228.87 ?  376  VAL A O   1 
ATOM   1947 C CB  . VAL A 1 376 ? 122.810 89.896  116.362 1.00 228.87 ?  376  VAL A CB  1 
ATOM   1948 C CG1 . VAL A 1 376 ? 123.360 89.690  117.763 1.00 228.87 ?  376  VAL A CG1 1 
ATOM   1949 C CG2 . VAL A 1 376 ? 122.566 91.367  116.079 1.00 228.87 ?  376  VAL A CG2 1 
ATOM   1950 N N   . ARG A 1 377 ? 123.402 90.072  113.027 1.00 232.24 ?  377  ARG A N   1 
ATOM   1951 C CA  . ARG A 1 377 ? 122.828 89.986  111.685 1.00 232.24 ?  377  ARG A CA  1 
ATOM   1952 C C   . ARG A 1 377 ? 123.806 89.431  110.651 1.00 232.24 ?  377  ARG A C   1 
ATOM   1953 O O   . ARG A 1 377 ? 123.406 88.697  109.750 1.00 232.24 ?  377  ARG A O   1 
ATOM   1954 C CB  . ARG A 1 377 ? 122.280 91.336  111.217 1.00 232.24 ?  377  ARG A CB  1 
ATOM   1955 C CG  . ARG A 1 377 ? 122.550 92.497  112.152 1.00 232.24 ?  377  ARG A CG  1 
ATOM   1956 C CD  . ARG A 1 377 ? 123.158 93.667  111.398 1.00 232.24 ?  377  ARG A CD  1 
ATOM   1957 N NE  . ARG A 1 377 ? 124.184 93.228  110.459 1.00 232.24 ?  377  ARG A NE  1 
ATOM   1958 C CZ  . ARG A 1 377 ? 124.533 93.899  109.368 1.00 232.24 ?  377  ARG A CZ  1 
ATOM   1959 N NH1 . ARG A 1 377 ? 125.476 93.422  108.568 1.00 232.24 1  377  ARG A NH1 1 
ATOM   1960 N NH2 . ARG A 1 377 ? 123.941 95.049  109.077 1.00 232.24 ?  377  ARG A NH2 1 
ATOM   1961 N N   . LYS A 1 378 ? 125.083 89.773  110.774 1.00 222.40 ?  378  LYS A N   1 
ATOM   1962 C CA  . LYS A 1 378 ? 126.064 89.319  109.795 1.00 222.40 ?  378  LYS A CA  1 
ATOM   1963 C C   . LYS A 1 378 ? 126.248 87.810  109.845 1.00 222.40 ?  378  LYS A C   1 
ATOM   1964 O O   . LYS A 1 378 ? 126.553 87.192  108.826 1.00 222.40 ?  378  LYS A O   1 
ATOM   1965 C CB  . LYS A 1 378 ? 127.402 90.062  109.940 1.00 222.40 ?  378  LYS A CB  1 
ATOM   1966 C CG  . LYS A 1 378 ? 128.320 89.550  111.038 1.00 222.40 ?  378  LYS A CG  1 
ATOM   1967 C CD  . LYS A 1 378 ? 129.637 89.041  110.478 1.00 222.40 ?  378  LYS A CD  1 
ATOM   1968 C CE  . LYS A 1 378 ? 130.039 87.735  111.141 1.00 222.40 ?  378  LYS A CE  1 
ATOM   1969 N NZ  . LYS A 1 378 ? 129.314 87.525  112.424 1.00 222.40 1  378  LYS A NZ  1 
ATOM   1970 N N   . HIS A 1 379 ? 126.063 87.207  111.013 1.00 220.23 ?  379  HIS A N   1 
ATOM   1971 C CA  . HIS A 1 379 ? 126.133 85.757  111.091 1.00 220.23 ?  379  HIS A CA  1 
ATOM   1972 C C   . HIS A 1 379 ? 124.826 85.231  110.530 1.00 220.23 ?  379  HIS A C   1 
ATOM   1973 O O   . HIS A 1 379 ? 123.770 85.439  111.121 1.00 220.23 ?  379  HIS A O   1 
ATOM   1974 C CB  . HIS A 1 379 ? 126.338 85.292  112.529 1.00 220.23 ?  379  HIS A CB  1 
ATOM   1975 C CG  . HIS A 1 379 ? 126.456 83.807  112.672 1.00 220.23 ?  379  HIS A CG  1 
ATOM   1976 N ND1 . HIS A 1 379 ? 126.091 83.140  113.822 1.00 220.23 ?  379  HIS A ND1 1 
ATOM   1977 C CD2 . HIS A 1 379 ? 126.900 82.860  111.813 1.00 220.23 ?  379  HIS A CD2 1 
ATOM   1978 C CE1 . HIS A 1 379 ? 126.303 81.846  113.664 1.00 220.23 ?  379  HIS A CE1 1 
ATOM   1979 N NE2 . HIS A 1 379 ? 126.794 81.649  112.454 1.00 220.23 ?  379  HIS A NE2 1 
ATOM   1980 N N   . LYS A 1 380 ? 124.887 84.562  109.384 1.00 238.70 ?  380  LYS A N   1 
ATOM   1981 C CA  . LYS A 1 380 ? 123.672 84.077  108.737 1.00 238.70 ?  380  LYS A CA  1 
ATOM   1982 C C   . LYS A 1 380 ? 122.791 83.243  109.655 1.00 238.70 ?  380  LYS A C   1 
ATOM   1983 O O   . LYS A 1 380 ? 121.606 83.530  109.807 1.00 238.70 ?  380  LYS A O   1 
ATOM   1984 C CB  . LYS A 1 380 ? 124.017 83.285  107.475 1.00 238.70 ?  380  LYS A CB  1 
ATOM   1985 C CG  . LYS A 1 380 ? 122.972 83.391  106.375 1.00 238.70 ?  380  LYS A CG  1 
ATOM   1986 C CD  . LYS A 1 380 ? 122.264 84.738  106.403 1.00 238.70 ?  380  LYS A CD  1 
ATOM   1987 C CE  . LYS A 1 380 ? 120.758 84.574  106.273 1.00 238.70 ?  380  LYS A CE  1 
ATOM   1988 N NZ  . LYS A 1 380 ? 120.050 84.898  107.542 1.00 238.70 1  380  LYS A NZ  1 
ATOM   1989 N N   . ALA A 1 381 ? 123.361 82.209  110.262 1.00 240.43 ?  381  ALA A N   1 
ATOM   1990 C CA  . ALA A 1 381 ? 122.589 81.352  111.153 1.00 240.43 ?  381  ALA A CA  1 
ATOM   1991 C C   . ALA A 1 381 ? 121.896 82.169  112.231 1.00 240.43 ?  381  ALA A C   1 
ATOM   1992 O O   . ALA A 1 381 ? 120.698 82.012  112.455 1.00 240.43 ?  381  ALA A O   1 
ATOM   1993 C CB  . ALA A 1 381 ? 123.482 80.295  111.779 1.00 240.43 ?  381  ALA A CB  1 
ATOM   1994 N N   . LEU A 1 382 ? 122.643 83.046  112.894 1.00 228.50 ?  382  LEU A N   1 
ATOM   1995 C CA  . LEU A 1 382 ? 122.069 83.874  113.946 1.00 228.50 ?  382  LEU A CA  1 
ATOM   1996 C C   . LEU A 1 382 ? 120.873 84.660  113.444 1.00 228.50 ?  382  LEU A C   1 
ATOM   1997 O O   . LEU A 1 382 ? 119.791 84.564  114.010 1.00 228.50 ?  382  LEU A O   1 
ATOM   1998 C CB  . LEU A 1 382 ? 123.113 84.835  114.506 1.00 228.50 ?  382  LEU A CB  1 
ATOM   1999 C CG  . LEU A 1 382 ? 123.154 84.981  116.024 1.00 228.50 ?  382  LEU A CG  1 
ATOM   2000 C CD1 . LEU A 1 382 ? 122.867 83.644  116.690 1.00 228.50 ?  382  LEU A CD1 1 
ATOM   2001 C CD2 . LEU A 1 382 ? 124.501 85.529  116.468 1.00 228.50 ?  382  LEU A CD2 1 
ATOM   2002 N N   . SER A 1 383 ? 121.062 85.435  112.383 1.00 247.68 ?  383  SER A N   1 
ATOM   2003 C CA  . SER A 1 383 ? 119.975 86.262  111.869 1.00 247.68 ?  383  SER A CA  1 
ATOM   2004 C C   . SER A 1 383 ? 118.753 85.434  111.509 1.00 247.68 ?  383  SER A C   1 
ATOM   2005 O O   . SER A 1 383 ? 117.639 85.799  111.862 1.00 247.68 ?  383  SER A O   1 
ATOM   2006 C CB  . SER A 1 383 ? 120.430 87.086  110.664 1.00 247.68 ?  383  SER A CB  1 
ATOM   2007 O OG  . SER A 1 383 ? 121.408 86.400  109.909 1.00 247.68 ?  383  SER A OG  1 
ATOM   2008 N N   . GLN A 1 384 ? 118.957 84.320  110.814 1.00 260.88 ?  384  GLN A N   1 
ATOM   2009 C CA  . GLN A 1 384 ? 117.847 83.454  110.431 1.00 260.88 ?  384  GLN A CA  1 
ATOM   2010 C C   . GLN A 1 384 ? 117.082 82.973  111.654 1.00 260.88 ?  384  GLN A C   1 
ATOM   2011 O O   . GLN A 1 384 ? 115.858 83.097  111.717 1.00 260.88 ?  384  GLN A O   1 
ATOM   2012 C CB  . GLN A 1 384 ? 118.369 82.261  109.627 1.00 260.88 ?  384  GLN A CB  1 
ATOM   2013 C CG  . GLN A 1 384 ? 117.394 81.103  109.491 1.00 260.88 ?  384  GLN A CG  1 
ATOM   2014 C CD  . GLN A 1 384 ? 117.888 79.843  110.177 1.00 260.88 ?  384  GLN A CD  1 
ATOM   2015 O OE1 . GLN A 1 384 ? 117.200 78.823  110.195 1.00 260.88 ?  384  GLN A OE1 1 
ATOM   2016 N NE2 . GLN A 1 384 ? 119.086 79.910  110.746 1.00 260.88 ?  384  GLN A NE2 1 
ATOM   2017 N N   . PHE A 1 385 ? 117.799 82.436  112.634 1.00 248.33 ?  385  PHE A N   1 
ATOM   2018 C CA  . PHE A 1 385 ? 117.163 81.952  113.851 1.00 248.33 ?  385  PHE A CA  1 
ATOM   2019 C C   . PHE A 1 385 ? 116.410 83.070  114.548 1.00 248.33 ?  385  PHE A C   1 
ATOM   2020 O O   . PHE A 1 385 ? 115.270 82.890  114.965 1.00 248.33 ?  385  PHE A O   1 
ATOM   2021 C CB  . PHE A 1 385 ? 118.223 81.380  114.789 1.00 248.33 ?  385  PHE A CB  1 
ATOM   2022 C CG  . PHE A 1 385 ? 117.665 80.570  115.921 1.00 248.33 ?  385  PHE A CG  1 
ATOM   2023 C CD1 . PHE A 1 385 ? 117.203 79.284  115.706 1.00 248.33 ?  385  PHE A CD1 1 
ATOM   2024 C CD2 . PHE A 1 385 ? 117.615 81.090  117.203 1.00 248.33 ?  385  PHE A CD2 1 
ATOM   2025 C CE1 . PHE A 1 385 ? 116.695 78.532  116.746 1.00 248.33 ?  385  PHE A CE1 1 
ATOM   2026 C CE2 . PHE A 1 385 ? 117.106 80.345  118.249 1.00 248.33 ?  385  PHE A CE2 1 
ATOM   2027 C CZ  . PHE A 1 385 ? 116.646 79.063  118.021 1.00 248.33 ?  385  PHE A CZ  1 
ATOM   2028 N N   . LEU A 1 386 ? 117.036 84.234  114.662 1.00 263.65 ?  386  LEU A N   1 
ATOM   2029 C CA  . LEU A 1 386 ? 116.414 85.348  115.368 1.00 263.65 ?  386  LEU A CA  1 
ATOM   2030 C C   . LEU A 1 386 ? 115.269 85.981  114.587 1.00 263.65 ?  386  LEU A C   1 
ATOM   2031 O O   . LEU A 1 386 ? 114.474 86.725  115.150 1.00 263.65 ?  386  LEU A O   1 
ATOM   2032 C CB  . LEU A 1 386 ? 117.461 86.410  115.709 1.00 263.65 ?  386  LEU A CB  1 
ATOM   2033 C CG  . LEU A 1 386 ? 118.099 86.370  117.100 1.00 263.65 ?  386  LEU A CG  1 
ATOM   2034 C CD1 . LEU A 1 386 ? 117.783 85.079  117.839 1.00 263.65 ?  386  LEU A CD1 1 
ATOM   2035 C CD2 . LEU A 1 386 ? 119.601 86.590  117.009 1.00 263.65 ?  386  LEU A CD2 1 
ATOM   2036 N N   . ALA A 1 387 ? 115.186 85.707  113.292 1.00 306.87 ?  387  ALA A N   1 
ATOM   2037 C CA  . ALA A 1 387 ? 114.079 86.227  112.502 1.00 306.87 ?  387  ALA A CA  1 
ATOM   2038 C C   . ALA A 1 387 ? 112.878 85.327  112.704 1.00 306.87 ?  387  ALA A C   1 
ATOM   2039 O O   . ALA A 1 387 ? 111.743 85.798  112.740 1.00 306.87 ?  387  ALA A O   1 
ATOM   2040 C CB  . ALA A 1 387 ? 114.453 86.302  111.033 1.00 306.87 ?  387  ALA A CB  1 
ATOM   2041 N N   . LYS A 1 388 ? 113.122 84.028  112.840 1.00 268.22 ?  388  LYS A N   1 
ATOM   2042 C CA  . LYS A 1 388 ? 112.032 83.099  113.101 1.00 268.22 ?  388  LYS A CA  1 
ATOM   2043 C C   . LYS A 1 388 ? 111.519 83.327  114.506 1.00 268.22 ?  388  LYS A C   1 
ATOM   2044 O O   . LYS A 1 388 ? 110.316 83.274  114.749 1.00 268.22 ?  388  LYS A O   1 
ATOM   2045 C CB  . LYS A 1 388 ? 112.509 81.658  112.946 1.00 268.22 ?  388  LYS A CB  1 
ATOM   2046 C CG  . LYS A 1 388 ? 112.753 81.244  111.505 1.00 268.22 ?  388  LYS A CG  1 
ATOM   2047 C CD  . LYS A 1 388 ? 113.847 80.195  111.405 1.00 268.22 ?  388  LYS A CD  1 
ATOM   2048 C CE  . LYS A 1 388 ? 114.208 79.643  112.773 1.00 268.22 ?  388  LYS A CE  1 
ATOM   2049 N NZ  . LYS A 1 388 ? 115.449 78.823  112.728 1.00 268.22 1  388  LYS A NZ  1 
ATOM   2050 N N   . HIS A 1 389 ? 112.430 83.582  115.436 1.00 274.50 ?  389  HIS A N   1 
ATOM   2051 C CA  . HIS A 1 389 ? 112.036 83.846  116.811 1.00 274.50 ?  389  HIS A CA  1 
ATOM   2052 C C   . HIS A 1 389 ? 112.469 85.246  117.188 1.00 274.50 ?  389  HIS A C   1 
ATOM   2053 O O   . HIS A 1 389 ? 113.545 85.436  117.746 1.00 274.50 ?  389  HIS A O   1 
ATOM   2054 C CB  . HIS A 1 389 ? 112.665 82.816  117.739 1.00 274.50 ?  389  HIS A CB  1 
ATOM   2055 C CG  . HIS A 1 389 ? 112.740 81.444  117.146 1.00 274.50 ?  389  HIS A CG  1 
ATOM   2056 N ND1 . HIS A 1 389 ? 111.621 80.680  116.896 1.00 274.50 ?  389  HIS A ND1 1 
ATOM   2057 C CD2 . HIS A 1 389 ? 113.798 80.705  116.740 1.00 274.50 ?  389  HIS A CD2 1 
ATOM   2058 C CE1 . HIS A 1 389 ? 111.987 79.527  116.367 1.00 274.50 ?  389  HIS A CE1 1 
ATOM   2059 N NE2 . HIS A 1 389 ? 113.303 79.516  116.262 1.00 274.50 ?  389  HIS A NE2 1 
ATOM   2060 N N   . ARG A 1 390 ? 111.635 86.233  116.884 1.00 261.05 ?  390  ARG A N   1 
ATOM   2061 C CA  . ARG A 1 390 ? 111.996 87.623  117.147 1.00 261.05 ?  390  ARG A CA  1 
ATOM   2062 C C   . ARG A 1 390 ? 112.159 87.948  118.622 1.00 261.05 ?  390  ARG A C   1 
ATOM   2063 O O   . ARG A 1 390 ? 112.919 88.844  118.971 1.00 261.05 ?  390  ARG A O   1 
ATOM   2064 C CB  . ARG A 1 390 ? 110.967 88.566  116.524 1.00 261.05 ?  390  ARG A CB  1 
ATOM   2065 C CG  . ARG A 1 390 ? 110.511 88.154  115.137 1.00 261.05 ?  390  ARG A CG  1 
ATOM   2066 C CD  . ARG A 1 390 ? 110.616 89.314  114.164 1.00 261.05 ?  390  ARG A CD  1 
ATOM   2067 N NE  . ARG A 1 390 ? 110.512 88.872  112.778 1.00 261.05 ?  390  ARG A NE  1 
ATOM   2068 C CZ  . ARG A 1 390 ? 111.446 89.079  111.858 1.00 261.05 ?  390  ARG A CZ  1 
ATOM   2069 N NH1 . ARG A 1 390 ? 112.560 89.724  112.175 1.00 261.05 1  390  ARG A NH1 1 
ATOM   2070 N NH2 . ARG A 1 390 ? 111.269 88.639  110.620 1.00 261.05 ?  390  ARG A NH2 1 
ATOM   2071 N N   . LEU A 1 391 ? 111.450 87.233  119.487 1.00 317.49 ?  391  LEU A N   1 
ATOM   2072 C CA  . LEU A 1 391 ? 111.513 87.518  120.915 1.00 317.49 ?  391  LEU A CA  1 
ATOM   2073 C C   . LEU A 1 391 ? 112.541 86.656  121.626 1.00 317.49 ?  391  LEU A C   1 
ATOM   2074 O O   . LEU A 1 391 ? 112.546 86.579  122.852 1.00 317.49 ?  391  LEU A O   1 
ATOM   2075 C CB  . LEU A 1 391 ? 110.141 87.342  121.564 1.00 317.49 ?  391  LEU A CB  1 
ATOM   2076 C CG  . LEU A 1 391 ? 109.032 88.292  121.112 1.00 317.49 ?  391  LEU A CG  1 
ATOM   2077 C CD1 . LEU A 1 391 ? 107.790 88.093  121.965 1.00 317.49 ?  391  LEU A CD1 1 
ATOM   2078 C CD2 . LEU A 1 391 ? 109.498 89.736  121.176 1.00 317.49 ?  391  LEU A CD2 1 
ATOM   2079 N N   . LEU A 1 392 ? 113.416 86.009  120.866 1.00 322.38 ?  392  LEU A N   1 
ATOM   2080 C CA  . LEU A 1 392 ? 114.464 85.197  121.469 1.00 322.38 ?  392  LEU A CA  1 
ATOM   2081 C C   . LEU A 1 392 ? 115.603 86.079  121.941 1.00 322.38 ?  392  LEU A C   1 
ATOM   2082 O O   . LEU A 1 392 ? 115.983 86.022  123.102 1.00 322.38 ?  392  LEU A O   1 
ATOM   2083 C CB  . LEU A 1 392 ? 114.984 84.151  120.486 1.00 322.38 ?  392  LEU A CB  1 
ATOM   2084 C CG  . LEU A 1 392 ? 115.159 82.735  121.030 1.00 322.38 ?  392  LEU A CG  1 
ATOM   2085 C CD1 . LEU A 1 392 ? 116.609 82.484  121.411 1.00 322.38 ?  392  LEU A CD1 1 
ATOM   2086 C CD2 . LEU A 1 392 ? 114.241 82.505  122.219 1.00 322.38 ?  392  LEU A CD2 1 
ATOM   2087 N N   . TYR A 1 393 ? 116.147 86.897  121.047 1.00 284.68 ?  393  TYR A N   1 
ATOM   2088 C CA  . TYR A 1 393 ? 117.227 87.802  121.427 1.00 284.68 ?  393  TYR A CA  1 
ATOM   2089 C C   . TYR A 1 393 ? 116.870 88.706  122.608 1.00 284.68 ?  393  TYR A C   1 
ATOM   2090 O O   . TYR A 1 393 ? 117.578 88.697  123.611 1.00 284.68 ?  393  TYR A O   1 
ATOM   2091 C CB  . TYR A 1 393 ? 117.747 88.613  120.235 1.00 284.68 ?  393  TYR A CB  1 
ATOM   2092 C CG  . TYR A 1 393 ? 119.019 89.371  120.528 1.00 284.68 ?  393  TYR A CG  1 
ATOM   2093 C CD1 . TYR A 1 393 ? 120.215 88.699  120.727 1.00 284.68 ?  393  TYR A CD1 1 
ATOM   2094 C CD2 . TYR A 1 393 ? 119.024 90.757  120.610 1.00 284.68 ?  393  TYR A CD2 1 
ATOM   2095 C CE1 . TYR A 1 393 ? 121.382 89.385  120.998 1.00 284.68 ?  393  TYR A CE1 1 
ATOM   2096 C CE2 . TYR A 1 393 ? 120.187 91.451  120.881 1.00 284.68 ?  393  TYR A CE2 1 
ATOM   2097 C CZ  . TYR A 1 393 ? 121.362 90.759  121.073 1.00 284.68 ?  393  TYR A CZ  1 
ATOM   2098 O OH  . TYR A 1 393 ? 122.525 91.440  121.344 1.00 284.68 ?  393  TYR A OH  1 
ATOM   2099 N N   . PRO A 1 394 ? 115.770 89.482  122.517 1.00 278.97 ?  394  PRO A N   1 
ATOM   2100 C CA  . PRO A 1 394 ? 115.471 90.284  123.706 1.00 278.97 ?  394  PRO A CA  1 
ATOM   2101 C C   . PRO A 1 394 ? 115.284 89.414  124.934 1.00 278.97 ?  394  PRO A C   1 
ATOM   2102 O O   . PRO A 1 394 ? 115.782 89.764  125.994 1.00 278.97 ?  394  PRO A O   1 
ATOM   2103 C CB  . PRO A 1 394 ? 114.162 90.993  123.346 1.00 278.97 ?  394  PRO A CB  1 
ATOM   2104 C CG  . PRO A 1 394 ? 113.621 90.281  122.161 1.00 278.97 ?  394  PRO A CG  1 
ATOM   2105 C CD  . PRO A 1 394 ? 114.811 89.749  121.432 1.00 278.97 ?  394  PRO A CD  1 
ATOM   2106 N N   . GLY A 1 395 ? 114.599 88.287  124.791 1.00 324.54 ?  395  GLY A N   1 
ATOM   2107 C CA  . GLY A 1 395 ? 114.394 87.383  125.904 1.00 324.54 ?  395  GLY A CA  1 
ATOM   2108 C C   . GLY A 1 395 ? 115.670 86.966  126.595 1.00 324.54 ?  395  GLY A C   1 
ATOM   2109 O O   . GLY A 1 395 ? 115.825 87.194  127.789 1.00 324.54 ?  395  GLY A O   1 
ATOM   2110 N N   . ILE A 1 396 ? 116.594 86.361  125.858 1.00 365.59 ?  396  ILE A N   1 
ATOM   2111 C CA  . ILE A 1 396 ? 117.818 85.867  126.478 1.00 365.59 ?  396  ILE A CA  1 
ATOM   2112 C C   . ILE A 1 396 ? 118.680 86.985  127.056 1.00 365.59 ?  396  ILE A C   1 
ATOM   2113 O O   . ILE A 1 396 ? 119.219 86.840  128.145 1.00 365.59 ?  396  ILE A O   1 
ATOM   2114 C CB  . ILE A 1 396 ? 118.644 84.956  125.537 1.00 365.59 ?  396  ILE A CB  1 
ATOM   2115 C CG1 . ILE A 1 396 ? 119.068 85.696  124.267 1.00 365.59 ?  396  ILE A CG1 1 
ATOM   2116 C CG2 . ILE A 1 396 ? 117.854 83.705  125.185 1.00 365.59 ?  396  ILE A CG2 1 
ATOM   2117 C CD1 . ILE A 1 396 ? 119.480 84.783  123.134 1.00 365.59 ?  396  ILE A CD1 1 
ATOM   2118 N N   . VAL A 1 397 ? 118.791 88.103  126.350 1.00 328.67 ?  397  VAL A N   1 
ATOM   2119 C CA  . VAL A 1 397 ? 119.582 89.213  126.847 1.00 328.67 ?  397  VAL A CA  1 
ATOM   2120 C C   . VAL A 1 397 ? 118.991 89.713  128.156 1.00 328.67 ?  397  VAL A C   1 
ATOM   2121 O O   . VAL A 1 397 ? 119.694 89.812  129.154 1.00 328.67 ?  397  VAL A O   1 
ATOM   2122 C CB  . VAL A 1 397 ? 119.691 90.347  125.813 1.00 328.67 ?  397  VAL A CB  1 
ATOM   2123 C CG1 . VAL A 1 397 ? 120.191 91.625  126.462 1.00 328.67 ?  397  VAL A CG1 1 
ATOM   2124 C CG2 . VAL A 1 397 ? 120.617 89.936  124.683 1.00 328.67 ?  397  VAL A CG2 1 
ATOM   2125 N N   . THR A 1 398 ? 117.694 89.992  128.170 1.00 299.27 ?  398  THR A N   1 
ATOM   2126 C CA  . THR A 1 398 ? 117.042 90.460  129.386 1.00 299.27 ?  398  THR A CA  1 
ATOM   2127 C C   . THR A 1 398 ? 117.229 89.466  130.512 1.00 299.27 ?  398  THR A C   1 
ATOM   2128 O O   . THR A 1 398 ? 117.568 89.845  131.628 1.00 299.27 ?  398  THR A O   1 
ATOM   2129 C CB  . THR A 1 398 ? 115.542 90.689  129.167 1.00 299.27 ?  398  THR A CB  1 
ATOM   2130 O OG1 . THR A 1 398 ? 115.357 91.553  128.043 1.00 299.27 ?  398  THR A OG1 1 
ATOM   2131 C CG2 . THR A 1 398 ? 114.921 91.326  130.382 1.00 299.27 ?  398  THR A CG2 1 
ATOM   2132 N N   . PHE A 1 399 ? 117.026 88.187  130.222 1.00 309.78 ?  399  PHE A N   1 
ATOM   2133 C CA  . PHE A 1 399 ? 117.155 87.170  131.249 1.00 309.78 ?  399  PHE A CA  1 
ATOM   2134 C C   . PHE A 1 399 ? 118.532 87.192  131.882 1.00 309.78 ?  399  PHE A C   1 
ATOM   2135 O O   . PHE A 1 399 ? 118.644 87.257  133.097 1.00 309.78 ?  399  PHE A O   1 
ATOM   2136 C CB  . PHE A 1 399 ? 116.863 85.779  130.697 1.00 309.78 ?  399  PHE A CB  1 
ATOM   2137 C CG  . PHE A 1 399 ? 116.889 84.704  131.742 1.00 309.78 ?  399  PHE A CG  1 
ATOM   2138 C CD1 . PHE A 1 399 ? 115.998 84.732  132.800 1.00 309.78 ?  399  PHE A CD1 1 
ATOM   2139 C CD2 . PHE A 1 399 ? 117.810 83.675  131.674 1.00 309.78 ?  399  PHE A CD2 1 
ATOM   2140 C CE1 . PHE A 1 399 ? 116.021 83.749  133.769 1.00 309.78 ?  399  PHE A CE1 1 
ATOM   2141 C CE2 . PHE A 1 399 ? 117.839 82.689  132.640 1.00 309.78 ?  399  PHE A CE2 1 
ATOM   2142 C CZ  . PHE A 1 399 ? 116.943 82.725  133.689 1.00 309.78 ?  399  PHE A CZ  1 
ATOM   2143 N N   . VAL A 1 400 ? 119.582 87.140  131.071 1.00 287.95 ?  400  VAL A N   1 
ATOM   2144 C CA  . VAL A 1 400 ? 120.925 87.083  131.632 1.00 287.95 ?  400  VAL A CA  1 
ATOM   2145 C C   . VAL A 1 400 ? 121.307 88.366  132.368 1.00 287.95 ?  400  VAL A C   1 
ATOM   2146 O O   . VAL A 1 400 ? 121.980 88.309  133.391 1.00 287.95 ?  400  VAL A O   1 
ATOM   2147 C CB  . VAL A 1 400 ? 121.997 86.666  130.598 1.00 287.95 ?  400  VAL A CB  1 
ATOM   2148 C CG1 . VAL A 1 400 ? 121.630 85.336  129.962 1.00 287.95 ?  400  VAL A CG1 1 
ATOM   2149 C CG2 . VAL A 1 400 ? 122.223 87.737  129.544 1.00 287.95 ?  400  VAL A CG2 1 
ATOM   2150 N N   . ILE A 1 401 ? 120.856 89.515  131.878 1.00 229.00 ?  401  ILE A N   1 
ATOM   2151 C CA  . ILE A 1 401 ? 121.138 90.769  132.559 1.00 229.00 ?  401  ILE A CA  1 
ATOM   2152 C C   . ILE A 1 401 ? 120.476 90.745  133.924 1.00 229.00 ?  401  ILE A C   1 
ATOM   2153 O O   . ILE A 1 401 ? 121.111 91.041  134.932 1.00 229.00 ?  401  ILE A O   1 
ATOM   2154 C CB  . ILE A 1 401 ? 120.646 91.981  131.748 1.00 229.00 ?  401  ILE A CB  1 
ATOM   2155 C CG1 . ILE A 1 401 ? 121.490 92.166  130.491 1.00 229.00 ?  401  ILE A CG1 1 
ATOM   2156 C CG2 . ILE A 1 401 ? 120.682 93.250  132.585 1.00 229.00 ?  401  ILE A CG2 1 
ATOM   2157 C CD1 . ILE A 1 401 ? 121.095 93.380  129.683 1.00 229.00 ?  401  ILE A CD1 1 
ATOM   2158 N N   . ALA A 1 402 ? 119.208 90.355  133.970 1.00 255.59 ?  402  ALA A N   1 
ATOM   2159 C CA  . ALA A 1 402 ? 118.479 90.332  135.231 1.00 255.59 ?  402  ALA A CA  1 
ATOM   2160 C C   . ALA A 1 402 ? 118.962 89.239  136.170 1.00 255.59 ?  402  ALA A C   1 
ATOM   2161 O O   . ALA A 1 402 ? 118.868 89.379  137.384 1.00 255.59 ?  402  ALA A O   1 
ATOM   2162 C CB  . ALA A 1 402 ? 116.991 90.199  134.978 1.00 255.59 ?  402  ALA A CB  1 
ATOM   2163 N N   . SER A 1 403 ? 119.489 88.154  135.618 1.00 271.02 ?  403  SER A N   1 
ATOM   2164 C CA  . SER A 1 403 ? 119.973 87.056  136.441 1.00 271.02 ?  403  SER A CA  1 
ATOM   2165 C C   . SER A 1 403 ? 121.313 87.396  137.058 1.00 271.02 ?  403  SER A C   1 
ATOM   2166 O O   . SER A 1 403 ? 121.703 86.813  138.066 1.00 271.02 ?  403  SER A O   1 
ATOM   2167 C CB  . SER A 1 403 ? 120.088 85.780  135.615 1.00 271.02 ?  403  SER A CB  1 
ATOM   2168 O OG  . SER A 1 403 ? 121.308 85.752  134.898 1.00 271.02 ?  403  SER A OG  1 
ATOM   2169 N N   . PHE A 1 404 ? 122.025 88.341  136.459 1.00 221.39 ?  404  PHE A N   1 
ATOM   2170 C CA  . PHE A 1 404 ? 123.307 88.757  137.003 1.00 221.39 ?  404  PHE A CA  1 
ATOM   2171 C C   . PHE A 1 404 ? 123.141 89.949  137.922 1.00 221.39 ?  404  PHE A C   1 
ATOM   2172 O O   . PHE A 1 404 ? 124.016 90.234  138.731 1.00 221.39 ?  404  PHE A O   1 
ATOM   2173 C CB  . PHE A 1 404 ? 124.284 89.084  135.881 1.00 221.39 ?  404  PHE A CB  1 
ATOM   2174 C CG  . PHE A 1 404 ? 125.111 87.916  135.443 1.00 221.39 ?  404  PHE A CG  1 
ATOM   2175 C CD1 . PHE A 1 404 ? 125.987 87.307  136.321 1.00 221.39 ?  404  PHE A CD1 1 
ATOM   2176 C CD2 . PHE A 1 404 ? 125.010 87.424  134.155 1.00 221.39 ?  404  PHE A CD2 1 
ATOM   2177 C CE1 . PHE A 1 404 ? 126.750 86.229  135.922 1.00 221.39 ?  404  PHE A CE1 1 
ATOM   2178 C CE2 . PHE A 1 404 ? 125.769 86.347  133.747 1.00 221.39 ?  404  PHE A CE2 1 
ATOM   2179 C CZ  . PHE A 1 404 ? 126.641 85.748  134.633 1.00 221.39 ?  404  PHE A CZ  1 
ATOM   2180 N N   . THR A 1 405 ? 122.021 90.650  137.809 1.00 183.45 ?  405  THR A N   1 
ATOM   2181 C CA  . THR A 1 405 ? 121.762 91.768  138.702 1.00 183.45 ?  405  THR A CA  1 
ATOM   2182 C C   . THR A 1 405 ? 120.939 91.316  139.888 1.00 183.45 ?  405  THR A C   1 
ATOM   2183 O O   . THR A 1 405 ? 120.629 92.123  140.753 1.00 183.45 ?  405  THR A O   1 
ATOM   2184 C CB  . THR A 1 405 ? 121.017 92.915  138.002 1.00 183.45 ?  405  THR A CB  1 
ATOM   2185 O OG1 . THR A 1 405 ? 119.880 92.399  137.307 1.00 183.45 ?  405  THR A OG1 1 
ATOM   2186 C CG2 . THR A 1 405 ? 121.925 93.632  137.028 1.00 183.45 ?  405  THR A CG2 1 
ATOM   2187 N N   . PHE A 1 406 ? 120.575 90.037  139.926 1.00 174.21 ?  406  PHE A N   1 
ATOM   2188 C CA  . PHE A 1 406 ? 119.793 89.492  141.032 1.00 174.21 ?  406  PHE A CA  1 
ATOM   2189 C C   . PHE A 1 406 ? 120.468 89.835  142.337 1.00 174.21 ?  406  PHE A C   1 
ATOM   2190 O O   . PHE A 1 406 ? 121.564 89.360  142.601 1.00 174.21 ?  406  PHE A O   1 
ATOM   2191 C CB  . PHE A 1 406 ? 119.669 87.979  140.879 1.00 174.21 ?  406  PHE A CB  1 
ATOM   2192 C CG  . PHE A 1 406 ? 118.764 87.336  141.885 1.00 174.21 ?  406  PHE A CG  1 
ATOM   2193 C CD1 . PHE A 1 406 ? 117.520 87.872  142.160 1.00 174.21 ?  406  PHE A CD1 1 
ATOM   2194 C CD2 . PHE A 1 406 ? 119.155 86.188  142.550 1.00 174.21 ?  406  PHE A CD2 1 
ATOM   2195 C CE1 . PHE A 1 406 ? 116.689 87.284  143.089 1.00 174.21 ?  406  PHE A CE1 1 
ATOM   2196 C CE2 . PHE A 1 406 ? 118.326 85.589  143.475 1.00 174.21 ?  406  PHE A CE2 1 
ATOM   2197 C CZ  . PHE A 1 406 ? 117.090 86.137  143.745 1.00 174.21 ?  406  PHE A CZ  1 
ATOM   2198 N N   . PRO A 1 407 ? 119.816 90.652  143.173 1.00 178.86 ?  407  PRO A N   1 
ATOM   2199 C CA  . PRO A 1 407 ? 120.488 91.099  144.398 1.00 178.86 ?  407  PRO A CA  1 
ATOM   2200 C C   . PRO A 1 407 ? 121.054 90.012  145.328 1.00 178.86 ?  407  PRO A C   1 
ATOM   2201 O O   . PRO A 1 407 ? 122.165 90.199  145.809 1.00 178.86 ?  407  PRO A O   1 
ATOM   2202 C CB  . PRO A 1 407 ? 119.434 91.977  145.083 1.00 178.86 ?  407  PRO A CB  1 
ATOM   2203 C CG  . PRO A 1 407 ? 118.513 92.390  143.988 1.00 178.86 ?  407  PRO A CG  1 
ATOM   2204 C CD  . PRO A 1 407 ? 118.469 91.229  143.044 1.00 178.86 ?  407  PRO A CD  1 
ATOM   2205 N N   . PRO A 1 408 ? 120.328 88.907  145.588 1.00 194.77 ?  408  PRO A N   1 
ATOM   2206 C CA  . PRO A 1 408 ? 120.963 87.890  146.435 1.00 194.77 ?  408  PRO A CA  1 
ATOM   2207 C C   . PRO A 1 408 ? 121.834 86.908  145.669 1.00 194.77 ?  408  PRO A C   1 
ATOM   2208 O O   . PRO A 1 408 ? 122.058 85.802  146.154 1.00 194.77 ?  408  PRO A O   1 
ATOM   2209 C CB  . PRO A 1 408 ? 119.771 87.135  147.033 1.00 194.77 ?  408  PRO A CB  1 
ATOM   2210 C CG  . PRO A 1 408 ? 118.587 88.006  146.804 1.00 194.77 ?  408  PRO A CG  1 
ATOM   2211 C CD  . PRO A 1 408 ? 118.881 88.671  145.502 1.00 194.77 ?  408  PRO A CD  1 
ATOM   2212 N N   . GLY A 1 409 ? 122.318 87.294  144.497 1.00 199.57 ?  409  GLY A N   1 
ATOM   2213 C CA  . GLY A 1 409 ? 123.138 86.410  143.698 1.00 199.57 ?  409  GLY A CA  1 
ATOM   2214 C C   . GLY A 1 409 ? 124.451 87.062  143.349 1.00 199.57 ?  409  GLY A C   1 
ATOM   2215 O O   . GLY A 1 409 ? 125.434 86.913  144.067 1.00 199.57 ?  409  GLY A O   1 
ATOM   2216 N N   . MET A 1 410 ? 124.478 87.786  142.241 1.00 185.66 ?  410  MET A N   1 
ATOM   2217 C CA  . MET A 1 410 ? 125.689 88.477  141.847 1.00 185.66 ?  410  MET A CA  1 
ATOM   2218 C C   . MET A 1 410 ? 125.475 89.961  142.020 1.00 185.66 ?  410  MET A C   1 
ATOM   2219 O O   . MET A 1 410 ? 126.424 90.734  142.009 1.00 185.66 ?  410  MET A O   1 
ATOM   2220 C CB  . MET A 1 410 ? 126.050 88.149  140.401 1.00 185.66 ?  410  MET A CB  1 
ATOM   2221 C CG  . MET A 1 410 ? 127.542 88.050  140.141 1.00 185.66 ?  410  MET A CG  1 
ATOM   2222 S SD  . MET A 1 410 ? 128.129 89.377  139.075 1.00 185.66 ?  410  MET A SD  1 
ATOM   2223 C CE  . MET A 1 410 ? 129.348 90.159  140.129 1.00 185.66 ?  410  MET A CE  1 
ATOM   2224 N N   . GLY A 1 411 ? 124.227 90.363  142.211 1.00 195.24 ?  411  GLY A N   1 
ATOM   2225 C CA  . GLY A 1 411 ? 123.917 91.766  142.387 1.00 195.24 ?  411  GLY A CA  1 
ATOM   2226 C C   . GLY A 1 411 ? 124.375 92.324  143.710 1.00 195.24 ?  411  GLY A C   1 
ATOM   2227 O O   . GLY A 1 411 ? 124.319 93.527  143.924 1.00 195.24 ?  411  GLY A O   1 
ATOM   2228 N N   . GLN A 1 412 ? 124.827 91.461  144.609 1.00 219.13 ?  412  GLN A N   1 
ATOM   2229 C CA  . GLN A 1 412 ? 125.344 91.923  145.884 1.00 219.13 ?  412  GLN A CA  1 
ATOM   2230 C C   . GLN A 1 412 ? 126.751 92.443  145.689 1.00 219.13 ?  412  GLN A C   1 
ATOM   2231 O O   . GLN A 1 412 ? 127.243 93.233  146.491 1.00 219.13 ?  412  GLN A O   1 
ATOM   2232 C CB  . GLN A 1 412 ? 125.347 90.787  146.896 1.00 219.13 ?  412  GLN A CB  1 
ATOM   2233 C CG  . GLN A 1 412 ? 125.460 89.408  146.278 1.00 219.13 ?  412  GLN A CG  1 
ATOM   2234 C CD  . GLN A 1 412 ? 125.583 88.316  147.318 1.00 219.13 ?  412  GLN A CD  1 
ATOM   2235 O OE1 . GLN A 1 412 ? 126.151 88.526  148.387 1.00 219.13 ?  412  GLN A OE1 1 
ATOM   2236 N NE2 . GLN A 1 412 ? 125.050 87.142  147.010 1.00 219.13 ?  412  GLN A NE2 1 
ATOM   2237 N N   . PHE A 1 413 ? 127.403 92.009  144.617 1.00 216.77 ?  413  PHE A N   1 
ATOM   2238 C CA  . PHE A 1 413 ? 128.770 92.426  144.354 1.00 216.77 ?  413  PHE A CA  1 
ATOM   2239 C C   . PHE A 1 413 ? 128.824 93.477  143.265 1.00 216.77 ?  413  PHE A C   1 
ATOM   2240 O O   . PHE A 1 413 ? 129.902 93.868  142.840 1.00 216.77 ?  413  PHE A O   1 
ATOM   2241 C CB  . PHE A 1 413 ? 129.619 91.231  143.930 1.00 216.77 ?  413  PHE A CB  1 
ATOM   2242 C CG  . PHE A 1 413 ? 129.403 90.005  144.761 1.00 216.77 ?  413  PHE A CG  1 
ATOM   2243 C CD1 . PHE A 1 413 ? 129.712 90.002  146.108 1.00 216.77 ?  413  PHE A CD1 1 
ATOM   2244 C CD2 . PHE A 1 413 ? 128.904 88.848  144.190 1.00 216.77 ?  413  PHE A CD2 1 
ATOM   2245 C CE1 . PHE A 1 413 ? 129.518 88.871  146.874 1.00 216.77 ?  413  PHE A CE1 1 
ATOM   2246 C CE2 . PHE A 1 413 ? 128.708 87.713  144.950 1.00 216.77 ?  413  PHE A CE2 1 
ATOM   2247 C CZ  . PHE A 1 413 ? 129.017 87.724  146.294 1.00 216.77 ?  413  PHE A CZ  1 
ATOM   2248 N N   . MET A 1 414 ? 127.667 93.932  142.808 1.00 192.46 ?  414  MET A N   1 
ATOM   2249 C CA  . MET A 1 414 ? 127.626 94.917  141.741 1.00 192.46 ?  414  MET A CA  1 
ATOM   2250 C C   . MET A 1 414 ? 126.481 95.895  141.915 1.00 192.46 ?  414  MET A C   1 
ATOM   2251 O O   . MET A 1 414 ? 126.126 96.584  140.971 1.00 192.46 ?  414  MET A O   1 
ATOM   2252 C CB  . MET A 1 414 ? 127.507 94.225  140.382 1.00 192.46 ?  414  MET A CB  1 
ATOM   2253 C CG  . MET A 1 414 ? 126.224 93.439  140.189 1.00 192.46 ?  414  MET A CG  1 
ATOM   2254 S SD  . MET A 1 414 ? 125.714 93.309  138.469 1.00 192.46 ?  414  MET A SD  1 
ATOM   2255 C CE  . MET A 1 414 ? 125.567 95.035  138.017 1.00 192.46 ?  414  MET A CE  1 
ATOM   2256 N N   . ALA A 1 415 ? 125.906 95.966  143.111 1.00 185.24 ?  415  ALA A N   1 
ATOM   2257 C CA  . ALA A 1 415 ? 124.753 96.837  143.352 1.00 185.24 ?  415  ALA A CA  1 
ATOM   2258 C C   . ALA A 1 415 ? 123.693 96.673  142.274 1.00 185.24 ?  415  ALA A C   1 
ATOM   2259 O O   . ALA A 1 415 ? 123.293 97.645  141.638 1.00 185.24 ?  415  ALA A O   1 
ATOM   2260 C CB  . ALA A 1 415 ? 125.177 98.291  143.479 1.00 185.24 ?  415  ALA A CB  1 
ATOM   2261 N N   . GLY A 1 416 ? 123.232 95.444  142.072 1.00 188.90 ?  416  GLY A N   1 
ATOM   2262 C CA  . GLY A 1 416 ? 122.225 95.184  141.062 1.00 188.90 ?  416  GLY A CA  1 
ATOM   2263 C C   . GLY A 1 416 ? 120.851 95.601  141.522 1.00 188.90 ?  416  GLY A C   1 
ATOM   2264 O O   . GLY A 1 416 ? 119.972 95.842  140.698 1.00 188.90 ?  416  GLY A O   1 
ATOM   2265 N N   . GLU A 1 417 ? 120.654 95.698  142.831 1.00 190.96 ?  417  GLU A N   1 
ATOM   2266 C CA  . GLU A 1 417 ? 119.378 96.156  143.363 1.00 190.96 ?  417  GLU A CA  1 
ATOM   2267 C C   . GLU A 1 417 ? 119.063 97.547  142.856 1.00 190.96 ?  417  GLU A C   1 
ATOM   2268 O O   . GLU A 1 417 ? 117.906 97.879  142.613 1.00 190.96 ?  417  GLU A O   1 
ATOM   2269 C CB  . GLU A 1 417 ? 119.423 96.177  144.887 1.00 190.96 ?  417  GLU A CB  1 
ATOM   2270 C CG  . GLU A 1 417 ? 118.060 96.082  145.551 1.00 190.96 ?  417  GLU A CG  1 
ATOM   2271 C CD  . GLU A 1 417 ? 118.091 95.259  146.821 1.00 190.96 ?  417  GLU A CD  1 
ATOM   2272 O OE1 . GLU A 1 417 ? 117.018 94.790  147.255 1.00 190.96 ?  417  GLU A OE1 1 
ATOM   2273 O OE2 . GLU A 1 417 ? 119.191 95.079  147.386 1.00 190.96 -1 417  GLU A OE2 1 
ATOM   2274 N N   . LEU A 1 418 ? 120.091 98.368  142.695 1.00 187.00 ?  418  LEU A N   1 
ATOM   2275 C CA  . LEU A 1 418 ? 119.889 99.734  142.245 1.00 187.00 ?  418  LEU A CA  1 
ATOM   2276 C C   . LEU A 1 418 ? 119.469 99.800  140.796 1.00 187.00 ?  418  LEU A C   1 
ATOM   2277 O O   . LEU A 1 418 ? 120.046 99.128  139.946 1.00 187.00 ?  418  LEU A O   1 
ATOM   2278 C CB  . LEU A 1 418 ? 121.165 100.543 142.444 1.00 187.00 ?  418  LEU A CB  1 
ATOM   2279 C CG  . LEU A 1 418 ? 121.430 100.984 143.876 1.00 187.00 ?  418  LEU A CG  1 
ATOM   2280 C CD1 . LEU A 1 418 ? 122.309 102.214 143.869 1.00 187.00 ?  418  LEU A CD1 1 
ATOM   2281 C CD2 . LEU A 1 418 ? 120.136 101.254 144.626 1.00 187.00 ?  418  LEU A CD2 1 
ATOM   2282 N N   . MET A 1 419 ? 118.465 100.615 140.510 1.00 204.53 ?  419  MET A N   1 
ATOM   2283 C CA  . MET A 1 419 ? 118.005 100.774 139.142 1.00 204.53 ?  419  MET A CA  1 
ATOM   2284 C C   . MET A 1 419 ? 118.750 101.954 138.544 1.00 204.53 ?  419  MET A C   1 
ATOM   2285 O O   . MET A 1 419 ? 119.299 102.753 139.287 1.00 204.53 ?  419  MET A O   1 
ATOM   2286 C CB  . MET A 1 419 ? 116.491 100.980 139.128 1.00 204.53 ?  419  MET A CB  1 
ATOM   2287 C CG  . MET A 1 419 ? 115.722 99.780  138.597 1.00 204.53 ?  419  MET A CG  1 
ATOM   2288 S SD  . MET A 1 419 ? 115.944 98.272  139.560 1.00 204.53 ?  419  MET A SD  1 
ATOM   2289 C CE  . MET A 1 419 ? 116.867 97.247  138.419 1.00 204.53 ?  419  MET A CE  1 
ATOM   2290 N N   . PRO A 1 420 ? 118.805 102.057 137.205 1.00 156.73 ?  420  PRO A N   1 
ATOM   2291 C CA  . PRO A 1 420 ? 119.577 103.127 136.564 1.00 156.73 ?  420  PRO A CA  1 
ATOM   2292 C C   . PRO A 1 420 ? 119.607 104.462 137.302 1.00 156.73 ?  420  PRO A C   1 
ATOM   2293 O O   . PRO A 1 420 ? 120.691 104.934 137.624 1.00 156.73 ?  420  PRO A O   1 
ATOM   2294 C CB  . PRO A 1 420 ? 118.878 103.275 135.219 1.00 156.73 ?  420  PRO A CB  1 
ATOM   2295 C CG  . PRO A 1 420 ? 118.369 101.899 134.913 1.00 156.73 ?  420  PRO A CG  1 
ATOM   2296 C CD  . PRO A 1 420 ? 118.284 101.116 136.199 1.00 156.73 ?  420  PRO A CD  1 
ATOM   2297 N N   . ARG A 1 421 ? 118.453 105.055 137.572 1.00 168.32 ?  421  ARG A N   1 
ATOM   2298 C CA  . ARG A 1 421 ? 118.406 106.361 138.223 1.00 168.32 ?  421  ARG A CA  1 
ATOM   2299 C C   . ARG A 1 421 ? 118.948 106.338 139.640 1.00 168.32 ?  421  ARG A C   1 
ATOM   2300 O O   . ARG A 1 421 ? 119.652 107.256 140.048 1.00 168.32 ?  421  ARG A O   1 
ATOM   2301 C CB  . ARG A 1 421 ? 116.980 106.899 138.221 1.00 168.32 ?  421  ARG A CB  1 
ATOM   2302 C CG  . ARG A 1 421 ? 116.265 106.716 136.895 1.00 168.32 ?  421  ARG A CG  1 
ATOM   2303 C CD  . ARG A 1 421 ? 116.307 107.990 136.069 1.00 168.32 ?  421  ARG A CD  1 
ATOM   2304 N NE  . ARG A 1 421 ? 114.985 108.594 135.955 1.00 168.32 ?  421  ARG A NE  1 
ATOM   2305 C CZ  . ARG A 1 421 ? 114.634 109.743 136.523 1.00 168.32 ?  421  ARG A CZ  1 
ATOM   2306 N NH1 . ARG A 1 421 ? 115.509 110.426 137.247 1.00 168.32 1  421  ARG A NH1 1 
ATOM   2307 N NH2 . ARG A 1 421 ? 113.406 110.207 136.364 1.00 168.32 ?  421  ARG A NH2 1 
ATOM   2308 N N   . GLU A 1 422 ? 118.626 105.295 140.395 1.00 196.80 ?  422  GLU A N   1 
ATOM   2309 C CA  . GLU A 1 422 ? 119.122 105.177 141.758 1.00 196.80 ?  422  GLU A CA  1 
ATOM   2310 C C   . GLU A 1 422 ? 120.629 105.063 141.763 1.00 196.80 ?  422  GLU A C   1 
ATOM   2311 O O   . GLU A 1 422 ? 121.284 105.598 142.645 1.00 196.80 ?  422  GLU A O   1 
ATOM   2312 C CB  . GLU A 1 422 ? 118.510 103.970 142.457 1.00 196.80 ?  422  GLU A CB  1 
ATOM   2313 C CG  . GLU A 1 422 ? 117.049 103.729 142.132 1.00 196.80 ?  422  GLU A CG  1 
ATOM   2314 C CD  . GLU A 1 422 ? 116.442 102.642 142.994 1.00 196.80 ?  422  GLU A CD  1 
ATOM   2315 O OE1 . GLU A 1 422 ? 115.542 102.955 143.799 1.00 196.80 ?  422  GLU A OE1 1 
ATOM   2316 O OE2 . GLU A 1 422 ? 116.867 101.476 142.872 1.00 196.80 -1 422  GLU A OE2 1 
ATOM   2317 N N   . ALA A 1 423 ? 121.187 104.374 140.776 1.00 179.55 ?  423  ALA A N   1 
ATOM   2318 C CA  . ALA A 1 423 ? 122.633 104.264 140.672 1.00 179.55 ?  423  ALA A CA  1 
ATOM   2319 C C   . ALA A 1 423 ? 123.260 105.638 140.562 1.00 179.55 ?  423  ALA A C   1 
ATOM   2320 O O   . ALA A 1 423 ? 124.130 105.978 141.343 1.00 179.55 ?  423  ALA A O   1 
ATOM   2321 C CB  . ALA A 1 423 ? 123.027 103.404 139.490 1.00 179.55 ?  423  ALA A CB  1 
ATOM   2322 N N   . ILE A 1 424 ? 122.806 106.440 139.607 1.00 178.19 ?  424  ILE A N   1 
ATOM   2323 C CA  . ILE A 1 424 ? 123.344 107.786 139.447 1.00 178.19 ?  424  ILE A CA  1 
ATOM   2324 C C   . ILE A 1 424 ? 123.152 108.636 140.694 1.00 178.19 ?  424  ILE A C   1 
ATOM   2325 O O   . ILE A 1 424 ? 124.028 109.404 141.060 1.00 178.19 ?  424  ILE A O   1 
ATOM   2326 C CB  . ILE A 1 424 ? 122.727 108.519 138.250 1.00 178.19 ?  424  ILE A CB  1 
ATOM   2327 C CG1 . ILE A 1 424 ? 122.394 107.541 137.136 1.00 178.19 ?  424  ILE A CG1 1 
ATOM   2328 C CG2 . ILE A 1 424 ? 123.682 109.568 137.716 1.00 178.19 ?  424  ILE A CG2 1 
ATOM   2329 C CD1 . ILE A 1 424 ? 121.968 108.214 135.854 1.00 178.19 ?  424  ILE A CD1 1 
ATOM   2330 N N   . SER A 1 425 ? 122.014 108.496 141.358 1.00 211.65 ?  425  SER A N   1 
ATOM   2331 C CA  . SER A 1 425 ? 121.740 109.291 142.546 1.00 211.65 ?  425  SER A CA  1 
ATOM   2332 C C   . SER A 1 425 ? 122.681 108.954 143.687 1.00 211.65 ?  425  SER A C   1 
ATOM   2333 O O   . SER A 1 425 ? 123.040 109.824 144.474 1.00 211.65 ?  425  SER A O   1 
ATOM   2334 C CB  . SER A 1 425 ? 120.293 109.102 142.988 1.00 211.65 ?  425  SER A CB  1 
ATOM   2335 O OG  . SER A 1 425 ? 120.199 108.169 144.048 1.00 211.65 ?  425  SER A OG  1 
ATOM   2336 N N   . THR A 1 426 ? 123.084 107.695 143.782 1.00 195.45 ?  426  THR A N   1 
ATOM   2337 C CA  . THR A 1 426 ? 123.982 107.275 144.846 1.00 195.45 ?  426  THR A CA  1 
ATOM   2338 C C   . THR A 1 426 ? 125.431 107.485 144.459 1.00 195.45 ?  426  THR A C   1 
ATOM   2339 O O   . THR A 1 426 ? 126.254 107.810 145.299 1.00 195.45 ?  426  THR A O   1 
ATOM   2340 C CB  . THR A 1 426 ? 123.778 105.800 145.192 1.00 195.45 ?  426  THR A CB  1 
ATOM   2341 O OG1 . THR A 1 426 ? 123.970 105.009 144.016 1.00 195.45 ?  426  THR A OG1 1 
ATOM   2342 C CG2 . THR A 1 426 ? 122.383 105.577 145.730 1.00 195.45 ?  426  THR A CG2 1 
ATOM   2343 N N   . LEU A 1 427 ? 125.752 107.312 143.184 1.00 191.14 ?  427  LEU A N   1 
ATOM   2344 C CA  . LEU A 1 427 ? 127.112 107.542 142.725 1.00 191.14 ?  427  LEU A CA  1 
ATOM   2345 C C   . LEU A 1 427 ? 127.441 109.022 142.788 1.00 191.14 ?  427  LEU A C   1 
ATOM   2346 O O   . LEU A 1 427 ? 128.604 109.395 142.833 1.00 191.14 ?  427  LEU A O   1 
ATOM   2347 C CB  . LEU A 1 427 ? 127.312 107.001 141.310 1.00 191.14 ?  427  LEU A CB  1 
ATOM   2348 C CG  . LEU A 1 427 ? 127.419 105.483 141.160 1.00 191.14 ?  427  LEU A CG  1 
ATOM   2349 C CD1 . LEU A 1 427 ? 127.030 105.038 139.760 1.00 191.14 ?  427  LEU A CD1 1 
ATOM   2350 C CD2 . LEU A 1 427 ? 128.811 104.992 141.507 1.00 191.14 ?  427  LEU A CD2 1 
ATOM   2351 N N   . PHE A 1 428 ? 126.421 109.871 142.807 1.00 213.07 ?  428  PHE A N   1 
ATOM   2352 C CA  . PHE A 1 428 ? 126.637 111.309 142.903 1.00 213.07 ?  428  PHE A CA  1 
ATOM   2353 C C   . PHE A 1 428 ? 126.423 111.758 144.341 1.00 213.07 ?  428  PHE A C   1 
ATOM   2354 O O   . PHE A 1 428 ? 125.976 112.874 144.580 1.00 213.07 ?  428  PHE A O   1 
ATOM   2355 C CB  . PHE A 1 428 ? 125.656 112.064 142.009 1.00 213.07 ?  428  PHE A CB  1 
ATOM   2356 C CG  . PHE A 1 428 ? 125.971 112.006 140.537 1.00 213.07 ?  428  PHE A CG  1 
ATOM   2357 C CD1 . PHE A 1 428 ? 126.948 111.165 140.037 1.00 213.07 ?  428  PHE A CD1 1 
ATOM   2358 C CD2 . PHE A 1 428 ? 125.269 112.802 139.649 1.00 213.07 ?  428  PHE A CD2 1 
ATOM   2359 C CE1 . PHE A 1 428 ? 127.217 111.118 138.685 1.00 213.07 ?  428  PHE A CE1 1 
ATOM   2360 C CE2 . PHE A 1 428 ? 125.537 112.765 138.295 1.00 213.07 ?  428  PHE A CE2 1 
ATOM   2361 C CZ  . PHE A 1 428 ? 126.514 111.921 137.813 1.00 213.07 ?  428  PHE A CZ  1 
ATOM   2362 N N   . ASP A 1 429 ? 126.727 110.893 145.303 1.00 254.83 ?  429  ASP A N   1 
ATOM   2363 C CA  . ASP A 1 429 ? 126.534 111.225 146.713 1.00 254.83 ?  429  ASP A CA  1 
ATOM   2364 C C   . ASP A 1 429 ? 127.623 112.123 147.250 1.00 254.83 ?  429  ASP A C   1 
ATOM   2365 O O   . ASP A 1 429 ? 128.706 112.209 146.677 1.00 254.83 ?  429  ASP A O   1 
ATOM   2366 C CB  . ASP A 1 429 ? 126.488 109.961 147.565 1.00 254.83 ?  429  ASP A CB  1 
ATOM   2367 C CG  . ASP A 1 429 ? 125.251 109.886 148.425 1.00 254.83 ?  429  ASP A CG  1 
ATOM   2368 O OD1 . ASP A 1 429 ? 124.154 110.193 147.915 1.00 254.83 ?  429  ASP A OD1 1 
ATOM   2369 O OD2 . ASP A 1 429 ? 125.375 109.518 149.611 1.00 254.83 -1 429  ASP A OD2 1 
ATOM   2370 N N   . ASN A 1 430 ? 127.352 112.774 148.372 1.00 236.43 ?  430  ASN A N   1 
ATOM   2371 C CA  . ASN A 1 430 ? 128.328 113.666 148.975 1.00 236.43 ?  430  ASN A CA  1 
ATOM   2372 C C   . ASN A 1 430 ? 129.117 112.949 150.054 1.00 236.43 ?  430  ASN A C   1 
ATOM   2373 O O   . ASN A 1 430 ? 129.714 113.584 150.919 1.00 236.43 ?  430  ASN A O   1 
ATOM   2374 C CB  . ASN A 1 430 ? 127.627 114.898 149.547 1.00 236.43 ?  430  ASN A CB  1 
ATOM   2375 C CG  . ASN A 1 430 ? 126.650 114.559 150.657 1.00 236.43 ?  430  ASN A CG  1 
ATOM   2376 O OD1 . ASN A 1 430 ? 125.819 113.661 150.521 1.00 236.43 ?  430  ASN A OD1 1 
ATOM   2377 N ND2 . ASN A 1 430 ? 126.742 115.286 151.763 1.00 236.43 ?  430  ASN A ND2 1 
ATOM   2378 N N   . ASN A 1 431 ? 129.133 111.624 150.002 1.00 238.46 ?  431  ASN A N   1 
ATOM   2379 C CA  . ASN A 1 431 ? 129.836 110.845 151.008 1.00 238.46 ?  431  ASN A CA  1 
ATOM   2380 C C   . ASN A 1 431 ? 131.100 110.222 150.456 1.00 238.46 ?  431  ASN A C   1 
ATOM   2381 O O   . ASN A 1 431 ? 131.417 110.400 149.283 1.00 238.46 ?  431  ASN A O   1 
ATOM   2382 C CB  . ASN A 1 431 ? 128.925 109.744 151.545 1.00 238.46 ?  431  ASN A CB  1 
ATOM   2383 C CG  . ASN A 1 431 ? 127.876 110.271 152.500 1.00 238.46 ?  431  ASN A CG  1 
ATOM   2384 O OD1 . ASN A 1 431 ? 126.704 109.905 152.416 1.00 238.46 ?  431  ASN A OD1 1 
ATOM   2385 N ND2 . ASN A 1 431 ? 128.293 111.134 153.417 1.00 238.46 ?  431  ASN A ND2 1 
ATOM   2386 N N   . THR A 1 432 ? 131.834 109.506 151.298 1.00 235.80 ?  432  THR A N   1 
ATOM   2387 C CA  . THR A 1 432 ? 133.035 108.815 150.853 1.00 235.80 ?  432  THR A CA  1 
ATOM   2388 C C   . THR A 1 432 ? 132.869 107.388 151.303 1.00 235.80 ?  432  THR A C   1 
ATOM   2389 O O   . THR A 1 432 ? 133.141 107.065 152.455 1.00 235.80 ?  432  THR A O   1 
ATOM   2390 C CB  . THR A 1 432 ? 134.303 109.404 151.481 1.00 235.80 ?  432  THR A CB  1 
ATOM   2391 O OG1 . THR A 1 432 ? 134.385 110.802 151.176 1.00 235.80 ?  432  THR A OG1 1 
ATOM   2392 C CG2 . THR A 1 432 ? 135.532 108.705 150.938 1.00 235.80 ?  432  THR A CG2 1 
ATOM   2393 N N   . TRP A 1 433 ? 132.417 106.522 150.410 1.00 195.77 ?  433  TRP A N   1 
ATOM   2394 C CA  . TRP A 1 433 ? 132.137 105.141 150.786 1.00 195.77 ?  433  TRP A CA  1 
ATOM   2395 C C   . TRP A 1 433 ? 133.323 104.416 151.387 1.00 195.77 ?  433  TRP A C   1 
ATOM   2396 O O   . TRP A 1 433 ? 133.150 103.524 152.211 1.00 195.77 ?  433  TRP A O   1 
ATOM   2397 C CB  . TRP A 1 433 ? 131.628 104.370 149.575 1.00 195.77 ?  433  TRP A CB  1 
ATOM   2398 C CG  . TRP A 1 433 ? 130.401 104.942 148.953 1.00 195.77 ?  433  TRP A CG  1 
ATOM   2399 C CD1 . TRP A 1 433 ? 129.466 105.729 149.553 1.00 195.77 ?  433  TRP A CD1 1 
ATOM   2400 C CD2 . TRP A 1 433 ? 129.968 104.765 147.602 1.00 195.77 ?  433  TRP A CD2 1 
ATOM   2401 N NE1 . TRP A 1 433 ? 128.480 106.058 148.661 1.00 195.77 ?  433  TRP A NE1 1 
ATOM   2402 C CE2 . TRP A 1 433 ? 128.764 105.475 147.455 1.00 195.77 ?  433  TRP A CE2 1 
ATOM   2403 C CE3 . TRP A 1 433 ? 130.482 104.077 146.503 1.00 195.77 ?  433  TRP A CE3 1 
ATOM   2404 C CZ2 . TRP A 1 433 ? 128.068 105.516 146.256 1.00 195.77 ?  433  TRP A CZ2 1 
ATOM   2405 C CZ3 . TRP A 1 433 ? 129.789 104.120 145.314 1.00 195.77 ?  433  TRP A CZ3 1 
ATOM   2406 C CH2 . TRP A 1 433 ? 128.597 104.837 145.198 1.00 195.77 ?  433  TRP A CH2 1 
ATOM   2407 N N   . VAL A 1 434 ? 134.528 104.791 150.983 1.00 221.24 ?  434  VAL A N   1 
ATOM   2408 C CA  . VAL A 1 434 ? 135.725 104.119 151.471 1.00 221.24 ?  434  VAL A CA  1 
ATOM   2409 C C   . VAL A 1 434 ? 135.970 104.396 152.954 1.00 221.24 ?  434  VAL A C   1 
ATOM   2410 O O   . VAL A 1 434 ? 136.601 103.593 153.642 1.00 221.24 ?  434  VAL A O   1 
ATOM   2411 C CB  . VAL A 1 434 ? 136.947 104.464 150.589 1.00 221.24 ?  434  VAL A CB  1 
ATOM   2412 C CG1 . VAL A 1 434 ? 137.921 105.399 151.292 1.00 221.24 ?  434  VAL A CG1 1 
ATOM   2413 C CG2 . VAL A 1 434 ? 137.631 103.196 150.111 1.00 221.24 ?  434  VAL A CG2 1 
ATOM   2414 N N   . LYS A 1 435 ? 135.443 105.506 153.458 1.00 239.32 ?  435  LYS A N   1 
ATOM   2415 C CA  . LYS A 1 435 ? 135.619 105.849 154.863 1.00 239.32 ?  435  LYS A CA  1 
ATOM   2416 C C   . LYS A 1 435 ? 134.473 105.313 155.705 1.00 239.32 ?  435  LYS A C   1 
ATOM   2417 O O   . LYS A 1 435 ? 134.675 104.901 156.844 1.00 239.32 ?  435  LYS A O   1 
ATOM   2418 C CB  . LYS A 1 435 ? 135.733 107.364 155.027 1.00 239.32 ?  435  LYS A CB  1 
ATOM   2419 C CG  . LYS A 1 435 ? 137.137 107.899 154.805 1.00 239.32 ?  435  LYS A CG  1 
ATOM   2420 C CD  . LYS A 1 435 ? 137.125 109.390 154.513 1.00 239.32 ?  435  LYS A CD  1 
ATOM   2421 C CE  . LYS A 1 435 ? 138.335 109.796 153.687 1.00 239.32 ?  435  LYS A CE  1 
ATOM   2422 N NZ  . LYS A 1 435 ? 139.149 108.618 153.281 1.00 239.32 1  435  LYS A NZ  1 
ATOM   2423 N N   . HIS A 1 436 ? 133.267 105.311 155.147 1.00 281.37 ?  436  HIS A N   1 
ATOM   2424 C CA  . HIS A 1 436 ? 132.105 104.813 155.874 1.00 281.37 ?  436  HIS A CA  1 
ATOM   2425 C C   . HIS A 1 436 ? 131.790 103.389 155.461 1.00 281.37 ?  436  HIS A C   1 
ATOM   2426 O O   . HIS A 1 436 ? 130.636 103.054 155.212 1.00 281.37 ?  436  HIS A O   1 
ATOM   2427 C CB  . HIS A 1 436 ? 130.882 105.699 155.635 1.00 281.37 ?  436  HIS A CB  1 
ATOM   2428 C CG  . HIS A 1 436 ? 131.209 107.139 155.387 1.00 281.37 ?  436  HIS A CG  1 
ATOM   2429 N ND1 . HIS A 1 436 ? 132.004 107.881 156.234 1.00 281.37 ?  436  HIS A ND1 1 
ATOM   2430 C CD2 . HIS A 1 436 ? 130.835 107.978 154.393 1.00 281.37 ?  436  HIS A CD2 1 
ATOM   2431 C CE1 . HIS A 1 436 ? 132.115 109.111 155.765 1.00 281.37 ?  436  HIS A CE1 1 
ATOM   2432 N NE2 . HIS A 1 436 ? 131.415 109.196 154.649 1.00 281.37 ?  436  HIS A NE2 1 
ATOM   2433 N N   . ALA A 1 437 ? 132.814 102.550 155.377 1.00 293.73 ?  437  ALA A N   1 
ATOM   2434 C CA  . ALA A 1 437 ? 132.605 101.157 155.015 1.00 293.73 ?  437  ALA A CA  1 
ATOM   2435 C C   . ALA A 1 437 ? 132.406 100.358 156.281 1.00 293.73 ?  437  ALA A C   1 
ATOM   2436 O O   . ALA A 1 437 ? 131.615 99.417  156.310 1.00 293.73 ?  437  ALA A O   1 
ATOM   2437 C CB  . ALA A 1 437 ? 133.789 100.626 154.228 1.00 293.73 ?  437  ALA A CB  1 
ATOM   2438 N N   . GLY A 1 438 ? 133.118 100.733 157.339 1.00 306.05 ?  438  GLY A N   1 
ATOM   2439 C CA  . GLY A 1 438 ? 132.943 100.066 158.617 1.00 306.05 ?  438  GLY A CA  1 
ATOM   2440 C C   . GLY A 1 438 ? 131.610 100.465 159.202 1.00 306.05 ?  438  GLY A C   1 
ATOM   2441 O O   . GLY A 1 438 ? 131.049 99.744  160.025 1.00 306.05 ?  438  GLY A O   1 
ATOM   2442 N N   . ASP A 1 439 ? 131.096 101.617 158.786 1.00 298.16 ?  439  ASP A N   1 
ATOM   2443 C CA  . ASP A 1 439 ? 129.784 102.050 159.242 1.00 298.16 ?  439  ASP A CA  1 
ATOM   2444 C C   . ASP A 1 439 ? 128.843 102.237 158.062 1.00 298.16 ?  439  ASP A C   1 
ATOM   2445 O O   . ASP A 1 439 ? 128.740 103.334 157.515 1.00 298.16 ?  439  ASP A O   1 
ATOM   2446 C CB  . ASP A 1 439 ? 129.890 103.355 160.030 1.00 298.16 ?  439  ASP A CB  1 
ATOM   2447 C CG  . ASP A 1 439 ? 128.567 103.772 160.644 1.00 298.16 ?  439  ASP A CG  1 
ATOM   2448 O OD1 . ASP A 1 439 ? 127.839 102.892 161.150 1.00 298.16 ?  439  ASP A OD1 1 
ATOM   2449 O OD2 . ASP A 1 439 ? 128.253 104.979 160.614 1.00 298.16 -1 439  ASP A OD2 1 
ATOM   2450 N N   . PRO A 1 440 ? 128.146 101.166 157.659 1.00 287.15 ?  440  PRO A N   1 
ATOM   2451 C CA  . PRO A 1 440 ? 127.159 101.329 156.594 1.00 287.15 ?  440  PRO A CA  1 
ATOM   2452 C C   . PRO A 1 440 ? 125.843 101.776 157.202 1.00 287.15 ?  440  PRO A C   1 
ATOM   2453 O O   . PRO A 1 440 ? 125.844 102.309 158.313 1.00 287.15 ?  440  PRO A O   1 
ATOM   2454 C CB  . PRO A 1 440 ? 127.021 99.916  156.017 1.00 287.15 ?  440  PRO A CB  1 
ATOM   2455 C CG  . PRO A 1 440 ? 127.732 98.995  156.964 1.00 287.15 ?  440  PRO A CG  1 
ATOM   2456 C CD  . PRO A 1 440 ? 128.184 99.784  158.156 1.00 287.15 ?  440  PRO A CD  1 
ATOM   2457 N N   . GLU A 1 441 ? 124.734 101.562 156.501 1.00 298.65 ?  441  GLU A N   1 
ATOM   2458 C CA  . GLU A 1 441 ? 123.421 101.978 156.996 1.00 298.65 ?  441  GLU A CA  1 
ATOM   2459 C C   . GLU A 1 441 ? 123.458 103.391 157.556 1.00 298.65 ?  441  GLU A C   1 
ATOM   2460 O O   . GLU A 1 441 ? 122.825 103.673 158.571 1.00 298.65 ?  441  GLU A O   1 
ATOM   2461 C CB  . GLU A 1 441 ? 122.899 101.002 158.055 1.00 298.65 ?  441  GLU A CB  1 
ATOM   2462 C CG  . GLU A 1 441 ? 123.161 99.537  157.748 1.00 298.65 ?  441  GLU A CG  1 
ATOM   2463 C CD  . GLU A 1 441 ? 124.170 98.918  158.697 1.00 298.65 ?  441  GLU A CD  1 
ATOM   2464 O OE1 . GLU A 1 441 ? 124.602 99.611  159.642 1.00 298.65 ?  441  GLU A OE1 1 
ATOM   2465 O OE2 . GLU A 1 441 ? 124.533 97.740  158.496 1.00 298.65 -1 441  GLU A OE2 1 
ATOM   2466 N N   . SER A 1 442 ? 124.194 104.280 156.900 1.00 305.90 ?  442  SER A N   1 
ATOM   2467 C CA  . SER A 1 442 ? 124.306 105.655 157.355 1.00 305.90 ?  442  SER A CA  1 
ATOM   2468 C C   . SER A 1 442 ? 124.482 106.485 156.113 1.00 305.90 ?  442  SER A C   1 
ATOM   2469 O O   . SER A 1 442 ? 124.392 107.711 156.155 1.00 305.90 ?  442  SER A O   1 
ATOM   2470 C CB  . SER A 1 442 ? 125.523 105.819 158.257 1.00 305.90 ?  442  SER A CB  1 
ATOM   2471 O OG  . SER A 1 442 ? 126.708 105.434 157.583 1.00 305.90 ?  442  SER A OG  1 
ATOM   2472 N N   . LEU A 1 443 ? 124.733 105.814 154.994 1.00 251.68 ?  443  LEU A N   1 
ATOM   2473 C CA  . LEU A 1 443 ? 124.922 106.512 153.732 1.00 251.68 ?  443  LEU A CA  1 
ATOM   2474 C C   . LEU A 1 443 ? 123.603 106.587 152.995 1.00 251.68 ?  443  LEU A C   1 
ATOM   2475 O O   . LEU A 1 443 ? 123.514 107.203 151.937 1.00 251.68 ?  443  LEU A O   1 
ATOM   2476 C CB  . LEU A 1 443 ? 125.962 105.788 152.888 1.00 251.68 ?  443  LEU A CB  1 
ATOM   2477 C CG  . LEU A 1 443 ? 127.230 105.365 153.623 1.00 251.68 ?  443  LEU A CG  1 
ATOM   2478 C CD1 . LEU A 1 443 ? 127.221 103.871 153.892 1.00 251.68 ?  443  LEU A CD1 1 
ATOM   2479 C CD2 . LEU A 1 443 ? 128.449 105.755 152.812 1.00 251.68 ?  443  LEU A CD2 1 
ATOM   2480 N N   . GLY A 1 444 ? 122.573 105.961 153.552 1.00 215.61 ?  444  GLY A N   1 
ATOM   2481 C CA  . GLY A 1 444 ? 121.259 106.012 152.942 1.00 215.61 ?  444  GLY A CA  1 
ATOM   2482 C C   . GLY A 1 444 ? 121.066 104.949 151.892 1.00 215.61 ?  444  GLY A C   1 
ATOM   2483 O O   . GLY A 1 444 ? 121.223 103.762 152.169 1.00 215.61 ?  444  GLY A O   1 
ATOM   2484 N N   . GLN A 1 445 ? 120.731 105.366 150.678 1.00 206.13 ?  445  GLN A N   1 
ATOM   2485 C CA  . GLN A 1 445 ? 120.555 104.417 149.588 1.00 206.13 ?  445  GLN A CA  1 
ATOM   2486 C C   . GLN A 1 445 ? 121.904 104.014 149.025 1.00 206.13 ?  445  GLN A C   1 
ATOM   2487 O O   . GLN A 1 445 ? 121.988 103.111 148.198 1.00 206.13 ?  445  GLN A O   1 
ATOM   2488 C CB  . GLN A 1 445 ? 119.692 105.030 148.492 1.00 206.13 ?  445  GLN A CB  1 
ATOM   2489 C CG  . GLN A 1 445 ? 118.491 104.186 148.108 1.00 206.13 ?  445  GLN A CG  1 
ATOM   2490 C CD  . GLN A 1 445 ? 118.270 104.140 146.611 1.00 206.13 ?  445  GLN A CD  1 
ATOM   2491 O OE1 . GLN A 1 445 ? 118.810 104.957 145.866 1.00 206.13 ?  445  GLN A OE1 1 
ATOM   2492 N NE2 . GLN A 1 445 ? 117.470 103.182 146.163 1.00 206.13 ?  445  GLN A NE2 1 
ATOM   2493 N N   . SER A 1 446 ? 122.963 104.673 149.478 1.00 199.99 ?  446  SER A N   1 
ATOM   2494 C CA  . SER A 1 446 ? 124.299 104.370 149.000 1.00 199.99 ?  446  SER A CA  1 
ATOM   2495 C C   . SER A 1 446 ? 124.959 103.314 149.862 1.00 199.99 ?  446  SER A C   1 
ATOM   2496 O O   . SER A 1 446 ? 126.160 103.090 149.759 1.00 199.99 ?  446  SER A O   1 
ATOM   2497 C CB  . SER A 1 446 ? 125.136 105.641 148.992 1.00 199.99 ?  446  SER A CB  1 
ATOM   2498 O OG  . SER A 1 446 ? 124.309 106.784 148.897 1.00 199.99 ?  446  SER A OG  1 
ATOM   2499 N N   . ALA A 1 447 ? 124.177 102.656 150.706 1.00 185.10 ?  447  ALA A N   1 
ATOM   2500 C CA  . ALA A 1 447 ? 124.714 101.612 151.568 1.00 185.10 ?  447  ALA A CA  1 
ATOM   2501 C C   . ALA A 1 447 ? 124.677 100.266 150.871 1.00 185.10 ?  447  ALA A C   1 
ATOM   2502 O O   . ALA A 1 447 ? 125.177 99.277  151.401 1.00 185.10 ?  447  ALA A O   1 
ATOM   2503 C CB  . ALA A 1 447 ? 123.940 101.556 152.870 1.00 185.10 ?  447  ALA A CB  1 
ATOM   2504 N N   . VAL A 1 448 ? 124.090 100.221 149.680 1.00 148.45 ?  448  VAL A N   1 
ATOM   2505 C CA  . VAL A 1 448 ? 124.043 98.983  148.913 1.00 148.45 ?  448  VAL A CA  1 
ATOM   2506 C C   . VAL A 1 448 ? 125.377 98.760  148.233 1.00 148.45 ?  448  VAL A C   1 
ATOM   2507 O O   . VAL A 1 448 ? 125.660 97.664  147.753 1.00 148.45 ?  448  VAL A O   1 
ATOM   2508 C CB  . VAL A 1 448 ? 122.945 99.035  147.842 1.00 148.45 ?  448  VAL A CB  1 
ATOM   2509 C CG1 . VAL A 1 448 ? 121.579 99.183  148.492 1.00 148.45 ?  448  VAL A CG1 1 
ATOM   2510 C CG2 . VAL A 1 448 ? 123.203 100.182 146.887 1.00 148.45 ?  448  VAL A CG2 1 
ATOM   2511 N N   . TRP A 1 449 ? 126.204 99.796  148.192 1.00 178.59 ?  449  TRP A N   1 
ATOM   2512 C CA  . TRP A 1 449 ? 127.507 99.686  147.568 1.00 178.59 ?  449  TRP A CA  1 
ATOM   2513 C C   . TRP A 1 449 ? 128.486 99.101  148.557 1.00 178.59 ?  449  TRP A C   1 
ATOM   2514 O O   . TRP A 1 449 ? 129.468 98.478  148.176 1.00 178.59 ?  449  TRP A O   1 
ATOM   2515 C CB  . TRP A 1 449 ? 127.980 101.057 147.108 1.00 178.59 ?  449  TRP A CB  1 
ATOM   2516 C CG  . TRP A 1 449 ? 127.148 101.629 146.021 1.00 178.59 ?  449  TRP A CG  1 
ATOM   2517 C CD1 . TRP A 1 449 ? 126.057 102.430 146.163 1.00 178.59 ?  449  TRP A CD1 1 
ATOM   2518 C CD2 . TRP A 1 449 ? 127.336 101.450 144.615 1.00 178.59 ?  449  TRP A CD2 1 
ATOM   2519 N NE1 . TRP A 1 449 ? 125.552 102.761 144.933 1.00 178.59 ?  449  TRP A NE1 1 
ATOM   2520 C CE2 . TRP A 1 449 ? 126.320 102.172 143.964 1.00 178.59 ?  449  TRP A CE2 1 
ATOM   2521 C CE3 . TRP A 1 449 ? 128.268 100.752 143.842 1.00 178.59 ?  449  TRP A CE3 1 
ATOM   2522 C CZ2 . TRP A 1 449 ? 126.205 102.213 142.580 1.00 178.59 ?  449  TRP A CZ2 1 
ATOM   2523 C CZ3 . TRP A 1 449 ? 128.153 100.794 142.471 1.00 178.59 ?  449  TRP A CZ3 1 
ATOM   2524 C CH2 . TRP A 1 449 ? 127.129 101.519 141.852 1.00 178.59 ?  449  TRP A CH2 1 
ATOM   2525 N N   . ILE A 1 450 ? 128.220 99.298  149.839 1.00 153.23 ?  450  ILE A N   1 
ATOM   2526 C CA  . ILE A 1 450 ? 129.088 98.737  150.858 1.00 153.23 ?  450  ILE A CA  1 
ATOM   2527 C C   . ILE A 1 450 ? 128.684 97.292  151.099 1.00 153.23 ?  450  ILE A C   1 
ATOM   2528 O O   . ILE A 1 450 ? 127.619 97.017  151.652 1.00 153.23 ?  450  ILE A O   1 
ATOM   2529 C CB  . ILE A 1 450 ? 129.073 99.568  152.158 1.00 153.23 ?  450  ILE A CB  1 
ATOM   2530 C CG1 . ILE A 1 450 ? 129.898 100.844 151.980 1.00 153.23 ?  450  ILE A CG1 1 
ATOM   2531 C CG2 . ILE A 1 450 ? 129.658 98.777  153.316 1.00 153.23 ?  450  ILE A CG2 1 
ATOM   2532 C CD1 . ILE A 1 450 ? 129.129 102.021 151.427 1.00 153.23 ?  450  ILE A CD1 1 
ATOM   2533 N N   . HIS A 1 451 ? 129.515 96.363  150.643 1.00 176.34 ?  451  HIS A N   1 
ATOM   2534 C CA  . HIS A 1 451 ? 129.231 94.953  150.848 1.00 176.34 ?  451  HIS A CA  1 
ATOM   2535 C C   . HIS A 1 451 ? 129.944 94.511  152.106 1.00 176.34 ?  451  HIS A C   1 
ATOM   2536 O O   . HIS A 1 451 ? 131.080 94.917  152.339 1.00 176.34 ?  451  HIS A O   1 
ATOM   2537 C CB  . HIS A 1 451 ? 129.710 94.134  149.649 1.00 176.34 ?  451  HIS A CB  1 
ATOM   2538 C CG  . HIS A 1 451 ? 129.314 92.693  149.703 1.00 176.34 ?  451  HIS A CG  1 
ATOM   2539 N ND1 . HIS A 1 451 ? 128.057 92.254  149.349 1.00 176.34 ?  451  HIS A ND1 1 
ATOM   2540 C CD2 . HIS A 1 451 ? 130.006 91.590  150.075 1.00 176.34 ?  451  HIS A CD2 1 
ATOM   2541 C CE1 . HIS A 1 451 ? 127.992 90.943  149.500 1.00 176.34 ?  451  HIS A CE1 1 
ATOM   2542 N NE2 . HIS A 1 451 ? 129.162 90.516  149.939 1.00 176.34 ?  451  HIS A NE2 1 
ATOM   2543 N N   . PRO A 1 452 ? 129.282 93.693  152.937 1.00 207.20 ?  452  PRO A N   1 
ATOM   2544 C CA  . PRO A 1 452 ? 129.901 93.181  154.162 1.00 207.20 ?  452  PRO A CA  1 
ATOM   2545 C C   . PRO A 1 452 ? 131.360 92.775  153.987 1.00 207.20 ?  452  PRO A C   1 
ATOM   2546 O O   . PRO A 1 452 ? 132.201 93.190  154.783 1.00 207.20 ?  452  PRO A O   1 
ATOM   2547 C CB  . PRO A 1 452 ? 129.057 91.949  154.471 1.00 207.20 ?  452  PRO A CB  1 
ATOM   2548 C CG  . PRO A 1 452 ? 127.708 92.259  153.904 1.00 207.20 ?  452  PRO A CG  1 
ATOM   2549 C CD  . PRO A 1 452 ? 127.855 93.336  152.861 1.00 207.20 ?  452  PRO A CD  1 
ATOM   2550 N N   . ARG A 1 453 ? 131.660 91.978  152.969 1.00 216.41 ?  453  ARG A N   1 
ATOM   2551 C CA  . ARG A 1 453 ? 133.025 91.519  152.748 1.00 216.41 ?  453  ARG A CA  1 
ATOM   2552 C C   . ARG A 1 453 ? 133.730 92.308  151.659 1.00 216.41 ?  453  ARG A C   1 
ATOM   2553 O O   . ARG A 1 453 ? 134.688 93.025  151.938 1.00 216.41 ?  453  ARG A O   1 
ATOM   2554 C CB  . ARG A 1 453 ? 133.028 90.034  152.395 1.00 216.41 ?  453  ARG A CB  1 
ATOM   2555 C CG  . ARG A 1 453 ? 131.986 89.218  153.139 1.00 216.41 ?  453  ARG A CG  1 
ATOM   2556 C CD  . ARG A 1 453 ? 131.154 88.387  152.179 1.00 216.41 ?  453  ARG A CD  1 
ATOM   2557 N NE  . ARG A 1 453 ? 131.863 88.132  150.929 1.00 216.41 ?  453  ARG A NE  1 
ATOM   2558 C CZ  . ARG A 1 453 ? 131.334 87.505  149.884 1.00 216.41 ?  453  ARG A CZ  1 
ATOM   2559 N NH1 . ARG A 1 453 ? 132.054 87.315  148.788 1.00 216.41 1  453  ARG A NH1 1 
ATOM   2560 N NH2 . ARG A 1 453 ? 130.083 87.068  149.935 1.00 216.41 ?  453  ARG A NH2 1 
ATOM   2561 N N   . VAL A 1 454 ? 133.266 92.183  150.421 1.00 199.01 ?  454  VAL A N   1 
ATOM   2562 C CA  . VAL A 1 454 ? 133.911 92.860  149.297 1.00 199.01 ?  454  VAL A CA  1 
ATOM   2563 C C   . VAL A 1 454 ? 134.031 94.368  149.488 1.00 199.01 ?  454  VAL A C   1 
ATOM   2564 O O   . VAL A 1 454 ? 133.045 95.041  149.776 1.00 199.01 ?  454  VAL A O   1 
ATOM   2565 C CB  . VAL A 1 454 ? 133.181 92.545  147.978 1.00 199.01 ?  454  VAL A CB  1 
ATOM   2566 C CG1 . VAL A 1 454 ? 134.009 92.979  146.782 1.00 199.01 ?  454  VAL A CG1 1 
ATOM   2567 C CG2 . VAL A 1 454 ? 132.875 91.059  147.894 1.00 199.01 ?  454  VAL A CG2 1 
ATOM   2568 N N   . ASN A 1 455 ? 135.238 94.901  149.327 1.00 173.98 ?  455  ASN A N   1 
ATOM   2569 C CA  . ASN A 1 455 ? 135.468 96.334  149.503 1.00 173.98 ?  455  ASN A CA  1 
ATOM   2570 C C   . ASN A 1 455 ? 134.713 97.156  148.476 1.00 173.98 ?  455  ASN A C   1 
ATOM   2571 O O   . ASN A 1 455 ? 134.639 96.768  147.318 1.00 173.98 ?  455  ASN A O   1 
ATOM   2572 C CB  . ASN A 1 455 ? 136.966 96.634  149.414 1.00 173.98 ?  455  ASN A CB  1 
ATOM   2573 C CG  . ASN A 1 455 ? 137.286 98.100  149.622 1.00 173.98 ?  455  ASN A CG  1 
ATOM   2574 O OD1 . ASN A 1 455 ? 136.744 98.747  150.517 1.00 173.98 ?  455  ASN A OD1 1 
ATOM   2575 N ND2 . ASN A 1 455 ? 138.174 98.631  148.794 1.00 173.98 ?  455  ASN A ND2 1 
ATOM   2576 N N   . VAL A 1 456 ? 134.169 98.296  148.890 1.00 157.56 ?  456  VAL A N   1 
ATOM   2577 C CA  . VAL A 1 456 ? 133.412 99.159  147.984 1.00 157.56 ?  456  VAL A CA  1 
ATOM   2578 C C   . VAL A 1 456 ? 134.052 99.340  146.621 1.00 157.56 ?  456  VAL A C   1 
ATOM   2579 O O   . VAL A 1 456 ? 133.385 99.192  145.609 1.00 157.56 ?  456  VAL A O   1 
ATOM   2580 C CB  . VAL A 1 456 ? 133.192 100.553 148.584 1.00 157.56 ?  456  VAL A CB  1 
ATOM   2581 C CG1 . VAL A 1 456 ? 131.795 101.042 148.251 1.00 157.56 ?  456  VAL A CG1 1 
ATOM   2582 C CG2 . VAL A 1 456 ? 133.415 100.525 150.087 1.00 157.56 ?  456  VAL A CG2 1 
ATOM   2583 N N   . VAL A 1 457 ? 135.338 99.665  146.588 1.00 156.78 ?  457  VAL A N   1 
ATOM   2584 C CA  . VAL A 1 457 ? 136.035 99.879  145.325 1.00 156.78 ?  457  VAL A CA  1 
ATOM   2585 C C   . VAL A 1 457 ? 135.834 98.715  144.365 1.00 156.78 ?  457  VAL A C   1 
ATOM   2586 O O   . VAL A 1 457 ? 135.529 98.917  143.193 1.00 156.78 ?  457  VAL A O   1 
ATOM   2587 C CB  . VAL A 1 457 ? 137.535 100.134 145.563 1.00 156.78 ?  457  VAL A CB  1 
ATOM   2588 C CG1 . VAL A 1 457 ? 138.274 100.307 144.247 1.00 156.78 ?  457  VAL A CG1 1 
ATOM   2589 C CG2 . VAL A 1 457 ? 137.721 101.363 146.437 1.00 156.78 ?  457  VAL A CG2 1 
ATOM   2590 N N   . ILE A 1 458 ? 135.974 97.493  144.860 1.00 182.65 ?  458  ILE A N   1 
ATOM   2591 C CA  . ILE A 1 458 ? 135.799 96.322  144.013 1.00 182.65 ?  458  ILE A CA  1 
ATOM   2592 C C   . ILE A 1 458 ? 134.361 96.144  143.535 1.00 182.65 ?  458  ILE A C   1 
ATOM   2593 O O   . ILE A 1 458 ? 134.139 95.693  142.419 1.00 182.65 ?  458  ILE A O   1 
ATOM   2594 C CB  . ILE A 1 458 ? 136.282 95.038  144.709 1.00 182.65 ?  458  ILE A CB  1 
ATOM   2595 C CG1 . ILE A 1 458 ? 137.437 95.356  145.658 1.00 182.65 ?  458  ILE A CG1 1 
ATOM   2596 C CG2 . ILE A 1 458 ? 136.715 94.002  143.685 1.00 182.65 ?  458  ILE A CG2 1 
ATOM   2597 C CD1 . ILE A 1 458 ? 137.982 94.143  146.377 1.00 182.65 ?  458  ILE A CD1 1 
ATOM   2598 N N   . ILE A 1 459 ? 133.381 96.504  144.356 1.00 168.11 ?  459  ILE A N   1 
ATOM   2599 C CA  . ILE A 1 459 ? 131.993 96.422  143.907 1.00 168.11 ?  459  ILE A CA  1 
ATOM   2600 C C   . ILE A 1 459 ? 131.659 97.496  142.872 1.00 168.11 ?  459  ILE A C   1 
ATOM   2601 O O   . ILE A 1 459 ? 130.854 97.253  141.980 1.00 168.11 ?  459  ILE A O   1 
ATOM   2602 C CB  . ILE A 1 459 ? 130.966 96.362  145.069 1.00 168.11 ?  459  ILE A CB  1 
ATOM   2603 C CG1 . ILE A 1 459 ? 130.059 97.590  145.088 1.00 168.11 ?  459  ILE A CG1 1 
ATOM   2604 C CG2 . ILE A 1 459 ? 131.649 96.142  146.406 1.00 168.11 ?  459  ILE A CG2 1 
ATOM   2605 C CD1 . ILE A 1 459 ? 128.593 97.235  144.998 1.00 168.11 ?  459  ILE A CD1 1 
ATOM   2606 N N   . ILE A 1 460 ? 132.291 98.664  142.955 1.00 157.05 ?  460  ILE A N   1 
ATOM   2607 C CA  . ILE A 1 460 ? 132.080 99.690  141.938 1.00 157.05 ?  460  ILE A CA  1 
ATOM   2608 C C   . ILE A 1 460 ? 132.738 99.210  140.662 1.00 157.05 ?  460  ILE A C   1 
ATOM   2609 O O   . ILE A 1 460 ? 132.226 99.432  139.570 1.00 157.05 ?  460  ILE A O   1 
ATOM   2610 C CB  . ILE A 1 460 ? 132.683 101.049 142.339 1.00 157.05 ?  460  ILE A CB  1 
ATOM   2611 C CG1 . ILE A 1 460 ? 132.242 101.454 143.740 1.00 157.05 ?  460  ILE A CG1 1 
ATOM   2612 C CG2 . ILE A 1 460 ? 132.251 102.133 141.371 1.00 157.05 ?  460  ILE A CG2 1 
ATOM   2613 C CD1 . ILE A 1 460 ? 133.117 102.527 144.348 1.00 157.05 ?  460  ILE A CD1 1 
ATOM   2614 N N   . PHE A 1 461 ? 133.871 98.535  140.795 1.00 201.00 ?  461  PHE A N   1 
ATOM   2615 C CA  . PHE A 1 461 ? 134.557 97.996  139.634 1.00 201.00 ?  461  PHE A CA  1 
ATOM   2616 C C   . PHE A 1 461 ? 133.690 96.949  138.972 1.00 201.00 ?  461  PHE A C   1 
ATOM   2617 O O   . PHE A 1 461 ? 133.521 96.958  137.760 1.00 201.00 ?  461  PHE A O   1 
ATOM   2618 C CB  . PHE A 1 461 ? 135.887 97.378  140.057 1.00 201.00 ?  461  PHE A CB  1 
ATOM   2619 C CG  . PHE A 1 461 ? 136.620 96.689  138.946 1.00 201.00 ?  461  PHE A CG  1 
ATOM   2620 C CD1 . PHE A 1 461 ? 137.158 97.414  137.899 1.00 201.00 ?  461  PHE A CD1 1 
ATOM   2621 C CD2 . PHE A 1 461 ? 136.779 95.314  138.956 1.00 201.00 ?  461  PHE A CD2 1 
ATOM   2622 C CE1 . PHE A 1 461 ? 137.836 96.782  136.877 1.00 201.00 ?  461  PHE A CE1 1 
ATOM   2623 C CE2 . PHE A 1 461 ? 137.454 94.674  137.937 1.00 201.00 ?  461  PHE A CE2 1 
ATOM   2624 C CZ  . PHE A 1 461 ? 137.985 95.409  136.896 1.00 201.00 ?  461  PHE A CZ  1 
ATOM   2625 N N   . LEU A 1 462 ? 133.132 96.046  139.766 1.00 190.40 ?  462  LEU A N   1 
ATOM   2626 C CA  . LEU A 1 462 ? 132.299 94.988  139.218 1.00 190.40 ?  462  LEU A CA  1 
ATOM   2627 C C   . LEU A 1 462 ? 131.038 95.568  138.620 1.00 190.40 ?  462  LEU A C   1 
ATOM   2628 O O   . LEU A 1 462 ? 130.559 95.072  137.616 1.00 190.40 ?  462  LEU A O   1 
ATOM   2629 C CB  . LEU A 1 462 ? 131.959 93.961  140.289 1.00 190.40 ?  462  LEU A CB  1 
ATOM   2630 C CG  . LEU A 1 462 ? 132.739 92.648  140.291 1.00 190.40 ?  462  LEU A CG  1 
ATOM   2631 C CD1 . LEU A 1 462 ? 133.888 92.688  139.297 1.00 190.40 ?  462  LEU A CD1 1 
ATOM   2632 C CD2 . LEU A 1 462 ? 133.239 92.331  141.691 1.00 190.40 ?  462  LEU A CD2 1 
ATOM   2633 N N   . PHE A 1 463 ? 130.496 96.620  139.221 1.00 168.22 ?  463  PHE A N   1 
ATOM   2634 C CA  . PHE A 1 463 ? 129.334 97.284  138.649 1.00 168.22 ?  463  PHE A CA  1 
ATOM   2635 C C   . PHE A 1 463 ? 129.705 97.753  137.262 1.00 168.22 ?  463  PHE A C   1 
ATOM   2636 O O   . PHE A 1 463 ? 129.028 97.433  136.302 1.00 168.22 ?  463  PHE A O   1 
ATOM   2637 C CB  . PHE A 1 463 ? 128.915 98.473  139.513 1.00 168.22 ?  463  PHE A CB  1 
ATOM   2638 C CG  . PHE A 1 463 ? 127.796 99.298  138.933 1.00 168.22 ?  463  PHE A CG  1 
ATOM   2639 C CD1 . PHE A 1 463 ? 126.481 98.893  139.057 1.00 168.22 ?  463  PHE A CD1 1 
ATOM   2640 C CD2 . PHE A 1 463 ? 128.058 100.493 138.291 1.00 168.22 ?  463  PHE A CD2 1 
ATOM   2641 C CE1 . PHE A 1 463 ? 125.452 99.653  138.541 1.00 168.22 ?  463  PHE A CE1 1 
ATOM   2642 C CE2 . PHE A 1 463 ? 127.036 101.258 137.767 1.00 168.22 ?  463  PHE A CE2 1 
ATOM   2643 C CZ  . PHE A 1 463 ? 125.730 100.838 137.893 1.00 168.22 ?  463  PHE A CZ  1 
ATOM   2644 N N   . PHE A 1 464 ? 130.793 98.501  137.152 1.00 193.47 ?  464  PHE A N   1 
ATOM   2645 C CA  . PHE A 1 464 ? 131.225 99.014  135.861 1.00 193.47 ?  464  PHE A CA  1 
ATOM   2646 C C   . PHE A 1 464 ? 131.416 97.904  134.840 1.00 193.47 ?  464  PHE A C   1 
ATOM   2647 O O   . PHE A 1 464 ? 130.920 98.003  133.728 1.00 193.47 ?  464  PHE A O   1 
ATOM   2648 C CB  . PHE A 1 464 ? 132.514 99.823  136.015 1.00 193.47 ?  464  PHE A CB  1 
ATOM   2649 C CG  . PHE A 1 464 ? 133.032 100.385 134.726 1.00 193.47 ?  464  PHE A CG  1 
ATOM   2650 C CD1 . PHE A 1 464 ? 132.452 101.506 134.170 1.00 193.47 ?  464  PHE A CD1 1 
ATOM   2651 C CD2 . PHE A 1 464 ? 134.096 99.791  134.072 1.00 193.47 ?  464  PHE A CD2 1 
ATOM   2652 C CE1 . PHE A 1 464 ? 132.919 102.028 132.983 1.00 193.47 ?  464  PHE A CE1 1 
ATOM   2653 C CE2 . PHE A 1 464 ? 134.567 100.306 132.883 1.00 193.47 ?  464  PHE A CE2 1 
ATOM   2654 C CZ  . PHE A 1 464 ? 133.977 101.428 132.339 1.00 193.47 ?  464  PHE A CZ  1 
ATOM   2655 N N   . VAL A 1 465 ? 132.134 96.852  135.207 1.00 202.93 ?  465  VAL A N   1 
ATOM   2656 C CA  . VAL A 1 465 ? 132.407 95.765  134.274 1.00 202.93 ?  465  VAL A CA  1 
ATOM   2657 C C   . VAL A 1 465 ? 131.124 95.073  133.856 1.00 202.93 ?  465  VAL A C   1 
ATOM   2658 O O   . VAL A 1 465 ? 130.863 94.891  132.664 1.00 202.93 ?  465  VAL A O   1 
ATOM   2659 C CB  . VAL A 1 465 ? 133.381 94.747  134.892 1.00 202.93 ?  465  VAL A CB  1 
ATOM   2660 C CG1 . VAL A 1 465 ? 133.438 93.470  134.068 1.00 202.93 ?  465  VAL A CG1 1 
ATOM   2661 C CG2 . VAL A 1 465 ? 134.763 95.360  135.014 1.00 202.93 ?  465  VAL A CG2 1 
ATOM   2662 N N   . MET A 1 466 ? 130.305 94.708  134.832 1.00 206.60 ?  466  MET A N   1 
ATOM   2663 C CA  . MET A 1 466 ? 129.059 94.024  134.535 1.00 206.60 ?  466  MET A CA  1 
ATOM   2664 C C   . MET A 1 466 ? 128.143 94.893  133.705 1.00 206.60 ?  466  MET A C   1 
ATOM   2665 O O   . MET A 1 466 ? 127.615 94.452  132.699 1.00 206.60 ?  466  MET A O   1 
ATOM   2666 C CB  . MET A 1 466 ? 128.362 93.599  135.820 1.00 206.60 ?  466  MET A CB  1 
ATOM   2667 C CG  . MET A 1 466 ? 128.220 92.097  135.981 1.00 206.60 ?  466  MET A CG  1 
ATOM   2668 S SD  . MET A 1 466 ? 129.797 91.235  135.896 1.00 206.60 ?  466  MET A SD  1 
ATOM   2669 C CE  . MET A 1 466 ? 129.261 89.627  135.319 1.00 206.60 ?  466  MET A CE  1 
ATOM   2670 N N   . LYS A 1 467 ? 127.966 96.140  134.109 1.00 171.12 ?  467  LYS A N   1 
ATOM   2671 C CA  . LYS A 1 467 ? 127.067 97.027  133.393 1.00 171.12 ?  467  LYS A CA  1 
ATOM   2672 C C   . LYS A 1 467 ? 127.629 97.493  132.063 1.00 171.12 ?  467  LYS A C   1 
ATOM   2673 O O   . LYS A 1 467 ? 126.912 98.085  131.274 1.00 171.12 ?  467  LYS A O   1 
ATOM   2674 C CB  . LYS A 1 467 ? 126.671 98.220  134.261 1.00 171.12 ?  467  LYS A CB  1 
ATOM   2675 C CG  . LYS A 1 467 ? 125.556 97.916  135.243 1.00 171.12 ?  467  LYS A CG  1 
ATOM   2676 C CD  . LYS A 1 467 ? 124.202 98.284  134.665 1.00 171.12 ?  467  LYS A CD  1 
ATOM   2677 C CE  . LYS A 1 467 ? 123.076 97.861  135.593 1.00 171.12 ?  467  LYS A CE  1 
ATOM   2678 N NZ  . LYS A 1 467 ? 122.229 96.800  134.983 1.00 171.12 1  467  LYS A NZ  1 
ATOM   2679 N N   . PHE A 1 468 ? 128.904 97.235  131.803 1.00 195.61 ?  468  PHE A N   1 
ATOM   2680 C CA  . PHE A 1 468 ? 129.477 97.585  130.513 1.00 195.61 ?  468  PHE A CA  1 
ATOM   2681 C C   . PHE A 1 468 ? 128.897 96.663  129.468 1.00 195.61 ?  468  PHE A C   1 
ATOM   2682 O O   . PHE A 1 468 ? 128.287 97.116  128.505 1.00 195.61 ?  468  PHE A O   1 
ATOM   2683 C CB  . PHE A 1 468 ? 130.997 97.461  130.531 1.00 195.61 ?  468  PHE A CB  1 
ATOM   2684 C CG  . PHE A 1 468 ? 131.697 98.411  129.607 1.00 195.61 ?  468  PHE A CG  1 
ATOM   2685 C CD1 . PHE A 1 468 ? 131.771 99.758  129.905 1.00 195.61 ?  468  PHE A CD1 1 
ATOM   2686 C CD2 . PHE A 1 468 ? 132.286 97.954  128.442 1.00 195.61 ?  468  PHE A CD2 1 
ATOM   2687 C CE1 . PHE A 1 468 ? 132.416 100.636 129.057 1.00 195.61 ?  468  PHE A CE1 1 
ATOM   2688 C CE2 . PHE A 1 468 ? 132.933 98.826  127.590 1.00 195.61 ?  468  PHE A CE2 1 
ATOM   2689 C CZ  . PHE A 1 468 ? 132.999 100.168 127.899 1.00 195.61 ?  468  PHE A CZ  1 
ATOM   2690 N N   . TRP A 1 469 ? 129.066 95.360  129.666 1.00 191.84 ?  469  TRP A N   1 
ATOM   2691 C CA  . TRP A 1 469 ? 128.498 94.404  128.724 1.00 191.84 ?  469  TRP A CA  1 
ATOM   2692 C C   . TRP A 1 469 ? 126.983 94.461  128.715 1.00 191.84 ?  469  TRP A C   1 
ATOM   2693 O O   . TRP A 1 469 ? 126.373 94.361  127.662 1.00 191.84 ?  469  TRP A O   1 
ATOM   2694 C CB  . TRP A 1 469 ? 129.020 92.974  128.944 1.00 191.84 ?  469  TRP A CB  1 
ATOM   2695 C CG  . TRP A 1 469 ? 128.586 92.278  130.200 1.00 191.84 ?  469  TRP A CG  1 
ATOM   2696 C CD1 . TRP A 1 469 ? 129.282 92.201  131.367 1.00 191.84 ?  469  TRP A CD1 1 
ATOM   2697 C CD2 . TRP A 1 469 ? 127.385 91.518  130.399 1.00 191.84 ?  469  TRP A CD2 1 
ATOM   2698 N NE1 . TRP A 1 469 ? 128.580 91.465  132.289 1.00 191.84 ?  469  TRP A NE1 1 
ATOM   2699 C CE2 . TRP A 1 469 ? 127.411 91.036  131.720 1.00 191.84 ?  469  TRP A CE2 1 
ATOM   2700 C CE3 . TRP A 1 469 ? 126.284 91.211  129.592 1.00 191.84 ?  469  TRP A CE3 1 
ATOM   2701 C CZ2 . TRP A 1 469 ? 126.384 90.262  132.252 1.00 191.84 ?  469  TRP A CZ2 1 
ATOM   2702 C CZ3 . TRP A 1 469 ? 125.264 90.449  130.124 1.00 191.84 ?  469  TRP A CZ3 1 
ATOM   2703 C CH2 . TRP A 1 469 ? 125.321 89.981  131.440 1.00 191.84 ?  469  TRP A CH2 1 
ATOM   2704 N N   . MET A 1 470 ? 126.375 94.643  129.879 1.00 169.44 ?  470  MET A N   1 
ATOM   2705 C CA  . MET A 1 470 ? 124.930 94.730  129.961 1.00 169.44 ?  470  MET A CA  1 
ATOM   2706 C C   . MET A 1 470 ? 124.416 95.852  129.087 1.00 169.44 ?  470  MET A C   1 
ATOM   2707 O O   . MET A 1 470 ? 123.498 95.655  128.304 1.00 169.44 ?  470  MET A O   1 
ATOM   2708 C CB  . MET A 1 470 ? 124.489 94.957  131.399 1.00 169.44 ?  470  MET A CB  1 
ATOM   2709 C CG  . MET A 1 470 ? 124.464 93.700  132.243 1.00 169.44 ?  470  MET A CG  1 
ATOM   2710 S SD  . MET A 1 470 ? 124.345 94.067  133.998 1.00 169.44 ?  470  MET A SD  1 
ATOM   2711 C CE  . MET A 1 470 ? 124.630 92.444  134.685 1.00 169.44 ?  470  MET A CE  1 
ATOM   2712 N N   . SER A 1 471 ? 125.012 97.031  129.208 1.00 148.38 ?  471  SER A N   1 
ATOM   2713 C CA  . SER A 1 471 ? 124.576 98.173  128.420 1.00 148.38 ?  471  SER A CA  1 
ATOM   2714 C C   . SER A 1 471 ? 124.808 97.958  126.934 1.00 148.38 ?  471  SER A C   1 
ATOM   2715 O O   . SER A 1 471 ? 123.980 98.337  126.118 1.00 148.38 ?  471  SER A O   1 
ATOM   2716 C CB  . SER A 1 471 ? 125.280 99.440  128.882 1.00 148.38 ?  471  SER A CB  1 
ATOM   2717 O OG  . SER A 1 471 ? 124.952 99.742  130.226 1.00 148.38 ?  471  SER A OG  1 
ATOM   2718 N N   . ILE A 1 472 ? 125.929 97.345  126.579 1.00 186.70 ?  472  ILE A N   1 
ATOM   2719 C CA  . ILE A 1 472 ? 126.231 97.088  125.178 1.00 186.70 ?  472  ILE A CA  1 
ATOM   2720 C C   . ILE A 1 472 ? 125.182 96.179  124.556 1.00 186.70 ?  472  ILE A C   1 
ATOM   2721 O O   . ILE A 1 472 ? 124.677 96.472  123.477 1.00 186.70 ?  472  ILE A O   1 
ATOM   2722 C CB  . ILE A 1 472 ? 127.652 96.502  125.009 1.00 186.70 ?  472  ILE A CB  1 
ATOM   2723 C CG1 . ILE A 1 472 ? 128.680 97.623  124.888 1.00 186.70 ?  472  ILE A CG1 1 
ATOM   2724 C CG2 . ILE A 1 472 ? 127.750 95.593  123.794 1.00 186.70 ?  472  ILE A CG2 1 
ATOM   2725 C CD1 . ILE A 1 472 ? 130.028 97.269  125.466 1.00 186.70 ?  472  ILE A CD1 1 
ATOM   2726 N N   . VAL A 1 473 ? 124.818 95.101  125.242 1.00 198.17 ?  473  VAL A N   1 
ATOM   2727 C CA  . VAL A 1 473 ? 123.869 94.144  124.675 1.00 198.17 ?  473  VAL A CA  1 
ATOM   2728 C C   . VAL A 1 473 ? 122.412 94.567  124.820 1.00 198.17 ?  473  VAL A C   1 
ATOM   2729 O O   . VAL A 1 473 ? 121.547 94.045  124.123 1.00 198.17 ?  473  VAL A O   1 
ATOM   2730 C CB  . VAL A 1 473 ? 124.080 92.720  125.231 1.00 198.17 ?  473  VAL A CB  1 
ATOM   2731 C CG1 . VAL A 1 473 ? 125.503 92.255  124.971 1.00 198.17 ?  473  VAL A CG1 1 
ATOM   2732 C CG2 . VAL A 1 473 ? 123.749 92.648  126.711 1.00 198.17 ?  473  VAL A CG2 1 
ATOM   2733 N N   . ALA A 1 474 ? 122.133 95.516  125.705 1.00 179.15 ?  474  ALA A N   1 
ATOM   2734 C CA  . ALA A 1 474 ? 120.772 96.011  125.866 1.00 179.15 ?  474  ALA A CA  1 
ATOM   2735 C C   . ALA A 1 474 ? 120.451 97.030  124.790 1.00 179.15 ?  474  ALA A C   1 
ATOM   2736 O O   . ALA A 1 474 ? 119.299 97.175  124.394 1.00 179.15 ?  474  ALA A O   1 
ATOM   2737 C CB  . ALA A 1 474 ? 120.588 96.617  127.241 1.00 179.15 ?  474  ALA A CB  1 
ATOM   2738 N N   . THR A 1 475 ? 121.472 97.729  124.311 1.00 160.89 ?  475  THR A N   1 
ATOM   2739 C CA  . THR A 1 475 ? 121.277 98.705  123.250 1.00 160.89 ?  475  THR A CA  1 
ATOM   2740 C C   . THR A 1 475 ? 121.269 98.009  121.897 1.00 160.89 ?  475  THR A C   1 
ATOM   2741 O O   . THR A 1 475 ? 121.137 98.661  120.866 1.00 160.89 ?  475  THR A O   1 
ATOM   2742 C CB  . THR A 1 475 ? 122.365 99.785  123.295 1.00 160.89 ?  475  THR A CB  1 
ATOM   2743 O OG1 . THR A 1 475 ? 123.655 99.164  123.304 1.00 160.89 ?  475  THR A OG1 1 
ATOM   2744 C CG2 . THR A 1 475 ? 122.221 100.612 124.549 1.00 160.89 ?  475  THR A CG2 1 
ATOM   2745 N N   . THR A 1 476 ? 121.404 96.688  121.894 1.00 196.92 ?  476  THR A N   1 
ATOM   2746 C CA  . THR A 1 476 ? 121.359 95.922  120.660 1.00 196.92 ?  476  THR A CA  1 
ATOM   2747 C C   . THR A 1 476 ? 119.993 95.271  120.510 1.00 196.92 ?  476  THR A C   1 
ATOM   2748 O O   . THR A 1 476 ? 119.633 94.803  119.431 1.00 196.92 ?  476  THR A O   1 
ATOM   2749 C CB  . THR A 1 476 ? 122.448 94.844  120.669 1.00 196.92 ?  476  THR A CB  1 
ATOM   2750 O OG1 . THR A 1 476 ? 123.641 95.392  121.236 1.00 196.92 ?  476  THR A OG1 1 
ATOM   2751 C CG2 . THR A 1 476 ? 122.752 94.360  119.265 1.00 196.92 ?  476  THR A CG2 1 
ATOM   2752 N N   . MET A 1 477 ? 119.213 95.256  121.585 1.00 192.79 ?  477  MET A N   1 
ATOM   2753 C CA  . MET A 1 477 ? 117.900 94.621  121.548 1.00 192.79 ?  477  MET A CA  1 
ATOM   2754 C C   . MET A 1 477 ? 116.946 95.345  120.610 1.00 192.79 ?  477  MET A C   1 
ATOM   2755 O O   . MET A 1 477 ? 117.066 96.554  120.422 1.00 192.79 ?  477  MET A O   1 
ATOM   2756 C CB  . MET A 1 477 ? 117.310 94.551  122.956 1.00 192.79 ?  477  MET A CB  1 
ATOM   2757 C CG  . MET A 1 477 ? 117.927 93.480  123.834 1.00 192.79 ?  477  MET A CG  1 
ATOM   2758 S SD  . MET A 1 477 ? 117.037 93.286  125.387 1.00 192.79 ?  477  MET A SD  1 
ATOM   2759 C CE  . MET A 1 477 ? 116.982 94.977  125.968 1.00 192.79 ?  477  MET A CE  1 
ATOM   2760 N N   . PRO A 1 478 ? 115.992 94.610  120.012 1.00 211.25 ?  478  PRO A N   1 
ATOM   2761 C CA  . PRO A 1 478 ? 115.010 95.215  119.101 1.00 211.25 ?  478  PRO A CA  1 
ATOM   2762 C C   . PRO A 1 478 ? 113.926 96.013  119.811 1.00 211.25 ?  478  PRO A C   1 
ATOM   2763 O O   . PRO A 1 478 ? 112.745 95.749  119.598 1.00 211.25 ?  478  PRO A O   1 
ATOM   2764 C CB  . PRO A 1 478 ? 114.383 94.001  118.418 1.00 211.25 ?  478  PRO A CB  1 
ATOM   2765 C CG  . PRO A 1 478 ? 114.572 92.882  119.379 1.00 211.25 ?  478  PRO A CG  1 
ATOM   2766 C CD  . PRO A 1 478 ? 115.897 93.140  120.028 1.00 211.25 ?  478  PRO A CD  1 
ATOM   2767 N N   . ILE A 1 479 ? 114.312 96.979  120.633 1.00 201.13 ?  479  ILE A N   1 
ATOM   2768 C CA  . ILE A 1 479 ? 113.359 97.786  121.372 1.00 201.13 ?  479  ILE A CA  1 
ATOM   2769 C C   . ILE A 1 479 ? 113.827 99.220  121.206 1.00 201.13 ?  479  ILE A C   1 
ATOM   2770 O O   . ILE A 1 479 ? 114.909 99.449  120.677 1.00 201.13 ?  479  ILE A O   1 
ATOM   2771 C CB  . ILE A 1 479 ? 113.375 97.406  122.867 1.00 201.13 ?  479  ILE A CB  1 
ATOM   2772 C CG1 . ILE A 1 479 ? 114.759 97.629  123.469 1.00 201.13 ?  479  ILE A CG1 1 
ATOM   2773 C CG2 . ILE A 1 479 ? 112.955 95.960  123.078 1.00 201.13 ?  479  ILE A CG2 1 
ATOM   2774 C CD1 . ILE A 1 479 ? 114.710 98.107  124.898 1.00 201.13 ?  479  ILE A CD1 1 
ATOM   2775 N N   . PRO A 1 480 ? 113.009 100.202 121.612 1.00 227.50 ?  480  PRO A N   1 
ATOM   2776 C CA  . PRO A 1 480 ? 113.521 101.574 121.556 1.00 227.50 ?  480  PRO A CA  1 
ATOM   2777 C C   . PRO A 1 480 ? 114.598 101.740 122.610 1.00 227.50 ?  480  PRO A C   1 
ATOM   2778 O O   . PRO A 1 480 ? 114.296 101.609 123.794 1.00 227.50 ?  480  PRO A O   1 
ATOM   2779 C CB  . PRO A 1 480 ? 112.306 102.416 121.928 1.00 227.50 ?  480  PRO A CB  1 
ATOM   2780 C CG  . PRO A 1 480 ? 111.138 101.577 121.576 1.00 227.50 ?  480  PRO A CG  1 
ATOM   2781 C CD  . PRO A 1 480 ? 111.561 100.169 121.866 1.00 227.50 ?  480  PRO A CD  1 
ATOM   2782 N N   . CYS A 1 481 ? 115.831 102.011 122.204 1.00 191.72 ?  481  CYS A N   1 
ATOM   2783 C CA  . CYS A 1 481 ? 116.921 102.099 123.166 1.00 191.72 ?  481  CYS A CA  1 
ATOM   2784 C C   . CYS A 1 481 ? 117.986 103.086 122.744 1.00 191.72 ?  481  CYS A C   1 
ATOM   2785 O O   . CYS A 1 481 ? 118.476 103.036 121.622 1.00 191.72 ?  481  CYS A O   1 
ATOM   2786 C CB  . CYS A 1 481 ? 117.555 100.722 123.384 1.00 191.72 ?  481  CYS A CB  1 
ATOM   2787 S SG  . CYS A 1 481 ? 117.902 99.792  121.876 1.00 191.72 ?  481  CYS A SG  1 
ATOM   2788 N N   . GLY A 1 482 ? 118.354 103.985 123.643 1.00 186.76 ?  482  GLY A N   1 
ATOM   2789 C CA  . GLY A 1 482 ? 119.403 104.940 123.347 1.00 186.76 ?  482  GLY A CA  1 
ATOM   2790 C C   . GLY A 1 482 ? 120.653 104.592 124.118 1.00 186.76 ?  482  GLY A C   1 
ATOM   2791 O O   . GLY A 1 482 ? 120.816 103.454 124.548 1.00 186.76 ?  482  GLY A O   1 
ATOM   2792 N N   . GLY A 1 483 ? 121.535 105.561 124.318 1.00 205.56 ?  483  GLY A N   1 
ATOM   2793 C CA  . GLY A 1 483 ? 122.791 105.259 124.974 1.00 205.56 ?  483  GLY A CA  1 
ATOM   2794 C C   . GLY A 1 483 ? 123.238 106.192 126.077 1.00 205.56 ?  483  GLY A C   1 
ATOM   2795 O O   . GLY A 1 483 ? 124.101 105.824 126.860 1.00 205.56 ?  483  GLY A O   1 
ATOM   2796 N N   . PHE A 1 484 ? 122.668 107.387 126.156 1.00 180.54 ?  484  PHE A N   1 
ATOM   2797 C CA  . PHE A 1 484 ? 123.122 108.355 127.147 1.00 180.54 ?  484  PHE A CA  1 
ATOM   2798 C C   . PHE A 1 484 ? 123.124 107.784 128.547 1.00 180.54 ?  484  PHE A C   1 
ATOM   2799 O O   . PHE A 1 484 ? 124.172 107.688 129.164 1.00 180.54 ?  484  PHE A O   1 
ATOM   2800 C CB  . PHE A 1 484 ? 122.268 109.614 127.124 1.00 180.54 ?  484  PHE A CB  1 
ATOM   2801 C CG  . PHE A 1 484 ? 122.948 110.823 127.700 1.00 180.54 ?  484  PHE A CG  1 
ATOM   2802 C CD1 . PHE A 1 484 ? 123.708 111.653 126.897 1.00 180.54 ?  484  PHE A CD1 1 
ATOM   2803 C CD2 . PHE A 1 484 ? 122.815 111.137 129.042 1.00 180.54 ?  484  PHE A CD2 1 
ATOM   2804 C CE1 . PHE A 1 484 ? 124.327 112.770 127.419 1.00 180.54 ?  484  PHE A CE1 1 
ATOM   2805 C CE2 . PHE A 1 484 ? 123.429 112.253 129.570 1.00 180.54 ?  484  PHE A CE2 1 
ATOM   2806 C CZ  . PHE A 1 484 ? 124.188 113.071 128.759 1.00 180.54 ?  484  PHE A CZ  1 
ATOM   2807 N N   . MET A 1 485 ? 121.956 107.416 129.059 1.00 207.53 ?  485  MET A N   1 
ATOM   2808 C CA  . MET A 1 485 ? 121.878 106.934 130.435 1.00 207.53 ?  485  MET A CA  1 
ATOM   2809 C C   . MET A 1 485 ? 122.705 105.687 130.738 1.00 207.53 ?  485  MET A C   1 
ATOM   2810 O O   . MET A 1 485 ? 123.390 105.651 131.748 1.00 207.53 ?  485  MET A O   1 
ATOM   2811 C CB  . MET A 1 485 ? 120.430 106.787 130.912 1.00 207.53 ?  485  MET A CB  1 
ATOM   2812 C CG  . MET A 1 485 ? 120.283 106.780 132.425 1.00 207.53 ?  485  MET A CG  1 
ATOM   2813 S SD  . MET A 1 485 ? 119.332 108.167 133.073 1.00 207.53 ?  485  MET A SD  1 
ATOM   2814 C CE  . MET A 1 485 ? 120.360 109.560 132.608 1.00 207.53 ?  485  MET A CE  1 
ATOM   2815 N N   . PRO A 1 486 ? 122.648 104.654 129.881 1.00 177.21 ?  486  PRO A N   1 
ATOM   2816 C CA  . PRO A 1 486 ? 123.530 103.525 130.185 1.00 177.21 ?  486  PRO A CA  1 
ATOM   2817 C C   . PRO A 1 486 ? 124.983 103.960 130.383 1.00 177.21 ?  486  PRO A C   1 
ATOM   2818 O O   . PRO A 1 486 ? 125.593 103.578 131.377 1.00 177.21 ?  486  PRO A O   1 
ATOM   2819 C CB  . PRO A 1 486 ? 123.401 102.654 128.943 1.00 177.21 ?  486  PRO A CB  1 
ATOM   2820 C CG  . PRO A 1 486 ? 122.018 102.893 128.470 1.00 177.21 ?  486  PRO A CG  1 
ATOM   2821 C CD  . PRO A 1 486 ? 121.687 104.316 128.813 1.00 177.21 ?  486  PRO A CD  1 
ATOM   2822 N N   . VAL A 1 487 ? 125.524 104.758 129.468 1.00 174.21 ?  487  VAL A N   1 
ATOM   2823 C CA  . VAL A 1 487 ? 126.911 105.209 129.566 1.00 174.21 ?  487  VAL A CA  1 
ATOM   2824 C C   . VAL A 1 487 ? 127.094 106.258 130.659 1.00 174.21 ?  487  VAL A C   1 
ATOM   2825 O O   . VAL A 1 487 ? 128.191 106.436 131.175 1.00 174.21 ?  487  VAL A O   1 
ATOM   2826 C CB  . VAL A 1 487 ? 127.418 105.717 128.202 1.00 174.21 ?  487  VAL A CB  1 
ATOM   2827 C CG1 . VAL A 1 487 ? 128.921 105.889 128.215 1.00 174.21 ?  487  VAL A CG1 1 
ATOM   2828 C CG2 . VAL A 1 487 ? 127.051 104.724 127.114 1.00 174.21 ?  487  VAL A CG2 1 
ATOM   2829 N N   . PHE A 1 488 ? 126.024 106.938 131.039 1.00 179.03 ?  488  PHE A N   1 
ATOM   2830 C CA  . PHE A 1 488 ? 126.095 107.910 132.122 1.00 179.03 ?  488  PHE A CA  1 
ATOM   2831 C C   . PHE A 1 488 ? 126.351 107.192 133.435 1.00 179.03 ?  488  PHE A C   1 
ATOM   2832 O O   . PHE A 1 488 ? 127.196 107.612 134.213 1.00 179.03 ?  488  PHE A O   1 
ATOM   2833 C CB  . PHE A 1 488 ? 124.784 108.676 132.213 1.00 179.03 ?  488  PHE A CB  1 
ATOM   2834 C CG  . PHE A 1 488 ? 124.914 110.057 132.770 1.00 179.03 ?  488  PHE A CG  1 
ATOM   2835 C CD1 . PHE A 1 488 ? 125.579 111.041 132.067 1.00 179.03 ?  488  PHE A CD1 1 
ATOM   2836 C CD2 . PHE A 1 488 ? 124.346 110.376 133.988 1.00 179.03 ?  488  PHE A CD2 1 
ATOM   2837 C CE1 . PHE A 1 488 ? 125.686 112.319 132.576 1.00 179.03 ?  488  PHE A CE1 1 
ATOM   2838 C CE2 . PHE A 1 488 ? 124.450 111.649 134.505 1.00 179.03 ?  488  PHE A CE2 1 
ATOM   2839 C CZ  . PHE A 1 488 ? 125.120 112.622 133.798 1.00 179.03 ?  488  PHE A CZ  1 
ATOM   2840 N N   . VAL A 1 489 ? 125.630 106.100 133.682 1.00 173.69 ?  489  VAL A N   1 
ATOM   2841 C CA  . VAL A 1 489 ? 125.851 105.329 134.902 1.00 173.69 ?  489  VAL A CA  1 
ATOM   2842 C C   . VAL A 1 489 ? 127.203 104.635 134.868 1.00 173.69 ?  489  VAL A C   1 
ATOM   2843 O O   . VAL A 1 489 ? 127.826 104.440 135.907 1.00 173.69 ?  489  VAL A O   1 
ATOM   2844 C CB  . VAL A 1 489 ? 124.708 104.329 135.218 1.00 173.69 ?  489  VAL A CB  1 
ATOM   2845 C CG1 . VAL A 1 489 ? 123.358 104.893 134.824 1.00 173.69 ?  489  VAL A CG1 1 
ATOM   2846 C CG2 . VAL A 1 489 ? 124.936 102.969 134.577 1.00 173.69 ?  489  VAL A CG2 1 
ATOM   2847 N N   . LEU A 1 490 ? 127.679 104.292 133.678 1.00 175.84 ?  490  LEU A N   1 
ATOM   2848 C CA  . LEU A 1 490 ? 128.973 103.647 133.553 1.00 175.84 ?  490  LEU A CA  1 
ATOM   2849 C C   . LEU A 1 490 ? 130.066 104.651 133.842 1.00 175.84 ?  490  LEU A C   1 
ATOM   2850 O O   . LEU A 1 490 ? 131.035 104.345 134.529 1.00 175.84 ?  490  LEU A O   1 
ATOM   2851 C CB  . LEU A 1 490 ? 129.145 103.073 132.153 1.00 175.84 ?  490  LEU A CB  1 
ATOM   2852 C CG  . LEU A 1 490 ? 128.432 101.749 131.928 1.00 175.84 ?  490  LEU A CG  1 
ATOM   2853 C CD1 . LEU A 1 490 ? 128.486 101.364 130.461 1.00 175.84 ?  490  LEU A CD1 1 
ATOM   2854 C CD2 . LEU A 1 490 ? 129.086 100.699 132.801 1.00 175.84 ?  490  LEU A CD2 1 
ATOM   2855 N N   . GLY A 1 491 ? 129.912 105.861 133.329 1.00 201.49 ?  491  GLY A N   1 
ATOM   2856 C CA  . GLY A 1 491 ? 130.891 106.892 133.582 1.00 201.49 ?  491  GLY A CA  1 
ATOM   2857 C C   . GLY A 1 491 ? 130.904 107.269 135.037 1.00 201.49 ?  491  GLY A C   1 
ATOM   2858 O O   . GLY A 1 491 ? 131.961 107.489 135.610 1.00 201.49 ?  491  GLY A O   1 
ATOM   2859 N N   . ALA A 1 492 ? 129.729 107.341 135.644 1.00 210.27 ?  492  ALA A N   1 
ATOM   2860 C CA  . ALA A 1 492 ? 129.640 107.684 137.049 1.00 210.27 ?  492  ALA A CA  1 
ATOM   2861 C C   . ALA A 1 492 ? 130.344 106.636 137.877 1.00 210.27 ?  492  ALA A C   1 
ATOM   2862 O O   . ALA A 1 492 ? 131.022 106.960 138.839 1.00 210.27 ?  492  ALA A O   1 
ATOM   2863 C CB  . ALA A 1 492 ? 128.190 107.811 137.466 1.00 210.27 ?  492  ALA A CB  1 
ATOM   2864 N N   . ALA A 1 493 ? 130.197 105.374 137.501 1.00 201.74 ?  493  ALA A N   1 
ATOM   2865 C CA  . ALA A 1 493 ? 130.860 104.302 138.219 1.00 201.74 ?  493  ALA A CA  1 
ATOM   2866 C C   . ALA A 1 493 ? 132.364 104.426 138.116 1.00 201.74 ?  493  ALA A C   1 
ATOM   2867 O O   . ALA A 1 493 ? 133.060 104.343 139.117 1.00 201.74 ?  493  ALA A O   1 
ATOM   2868 C CB  . ALA A 1 493 ? 130.410 102.963 137.686 1.00 201.74 ?  493  ALA A CB  1 
ATOM   2869 N N   . PHE A 1 494 ? 132.872 104.630 136.909 1.00 215.80 ?  494  PHE A N   1 
ATOM   2870 C CA  . PHE A 1 494 ? 134.306 104.797 136.727 1.00 215.80 ?  494  PHE A CA  1 
ATOM   2871 C C   . PHE A 1 494 ? 134.809 105.998 137.506 1.00 215.80 ?  494  PHE A C   1 
ATOM   2872 O O   . PHE A 1 494 ? 135.800 105.906 138.220 1.00 215.80 ?  494  PHE A O   1 
ATOM   2873 C CB  . PHE A 1 494 ? 134.658 104.948 135.251 1.00 215.80 ?  494  PHE A CB  1 
ATOM   2874 C CG  . PHE A 1 494 ? 136.130 104.956 134.988 1.00 215.80 ?  494  PHE A CG  1 
ATOM   2875 C CD1 . PHE A 1 494 ? 136.868 103.794 135.109 1.00 215.80 ?  494  PHE A CD1 1 
ATOM   2876 C CD2 . PHE A 1 494 ? 136.781 106.127 134.642 1.00 215.80 ?  494  PHE A CD2 1 
ATOM   2877 C CE1 . PHE A 1 494 ? 138.228 103.795 134.879 1.00 215.80 ?  494  PHE A CE1 1 
ATOM   2878 C CE2 . PHE A 1 494 ? 138.139 106.137 134.412 1.00 215.80 ?  494  PHE A CE2 1 
ATOM   2879 C CZ  . PHE A 1 494 ? 138.864 104.969 134.532 1.00 215.80 ?  494  PHE A CZ  1 
ATOM   2880 N N   . GLY A 1 495 ? 134.128 107.127 137.373 1.00 214.99 ?  495  GLY A N   1 
ATOM   2881 C CA  . GLY A 1 495 ? 134.518 108.314 138.099 1.00 214.99 ?  495  GLY A CA  1 
ATOM   2882 C C   . GLY A 1 495 ? 134.543 108.083 139.591 1.00 214.99 ?  495  GLY A C   1 
ATOM   2883 O O   . GLY A 1 495 ? 135.490 108.474 140.259 1.00 214.99 ?  495  GLY A O   1 
ATOM   2884 N N   . ARG A 1 496 ? 133.510 107.443 140.123 1.00 225.16 ?  496  ARG A N   1 
ATOM   2885 C CA  . ARG A 1 496 ? 133.449 107.177 141.551 1.00 225.16 ?  496  ARG A CA  1 
ATOM   2886 C C   . ARG A 1 496 ? 134.574 106.263 141.971 1.00 225.16 ?  496  ARG A C   1 
ATOM   2887 O O   . ARG A 1 496 ? 135.197 106.494 142.991 1.00 225.16 ?  496  ARG A O   1 
ATOM   2888 C CB  . ARG A 1 496 ? 132.111 106.563 141.941 1.00 225.16 ?  496  ARG A CB  1 
ATOM   2889 C CG  . ARG A 1 496 ? 131.893 106.450 143.436 1.00 225.16 ?  496  ARG A CG  1 
ATOM   2890 C CD  . ARG A 1 496 ? 131.226 107.694 143.984 1.00 225.16 ?  496  ARG A CD  1 
ATOM   2891 N NE  . ARG A 1 496 ? 131.281 107.738 145.438 1.00 225.16 ?  496  ARG A NE  1 
ATOM   2892 C CZ  . ARG A 1 496 ? 130.432 108.419 146.197 1.00 225.16 ?  496  ARG A CZ  1 
ATOM   2893 N NH1 . ARG A 1 496 ? 129.455 109.113 145.639 1.00 225.16 1  496  ARG A NH1 1 
ATOM   2894 N NH2 . ARG A 1 496 ? 130.559 108.402 147.513 1.00 225.16 ?  496  ARG A NH2 1 
ATOM   2895 N N   . LEU A 1 497 ? 134.845 105.228 141.189 1.00 207.47 ?  497  LEU A N   1 
ATOM   2896 C CA  . LEU A 1 497 ? 135.952 104.334 141.493 1.00 207.47 ?  497  LEU A CA  1 
ATOM   2897 C C   . LEU A 1 497 ? 137.223 105.143 141.651 1.00 207.47 ?  497  LEU A C   1 
ATOM   2898 O O   . LEU A 1 497 ? 137.906 105.024 142.660 1.00 207.47 ?  497  LEU A O   1 
ATOM   2899 C CB  . LEU A 1 497 ? 136.109 103.286 140.394 1.00 207.47 ?  497  LEU A CB  1 
ATOM   2900 C CG  . LEU A 1 497 ? 137.366 102.425 140.337 1.00 207.47 ?  497  LEU A CG  1 
ATOM   2901 C CD1 . LEU A 1 497 ? 137.024 100.995 140.709 1.00 207.47 ?  497  LEU A CD1 1 
ATOM   2902 C CD2 . LEU A 1 497 ? 137.965 102.483 138.942 1.00 207.47 ?  497  LEU A CD2 1 
ATOM   2903 N N   . VAL A 1 498 ? 137.533 105.986 140.671 1.00 210.38 ?  498  VAL A N   1 
ATOM   2904 C CA  . VAL A 1 498 ? 138.713 106.839 140.762 1.00 210.38 ?  498  VAL A CA  1 
ATOM   2905 C C   . VAL A 1 498 ? 138.668 107.695 142.017 1.00 210.38 ?  498  VAL A C   1 
ATOM   2906 O O   . VAL A 1 498 ? 139.628 107.730 142.771 1.00 210.38 ?  498  VAL A O   1 
ATOM   2907 C CB  . VAL A 1 498 ? 138.866 107.731 139.517 1.00 210.38 ?  498  VAL A CB  1 
ATOM   2908 C CG1 . VAL A 1 498 ? 140.045 108.680 139.671 1.00 210.38 ?  498  VAL A CG1 1 
ATOM   2909 C CG2 . VAL A 1 498 ? 139.038 106.872 138.275 1.00 210.38 ?  498  VAL A CG2 1 
ATOM   2910 N N   . GLY A 1 499 ? 137.549 108.364 142.259 1.00 215.52 ?  499  GLY A N   1 
ATOM   2911 C CA  . GLY A 1 499 ? 137.411 109.202 143.435 1.00 215.52 ?  499  GLY A CA  1 
ATOM   2912 C C   . GLY A 1 499 ? 137.564 108.485 144.756 1.00 215.52 ?  499  GLY A C   1 
ATOM   2913 O O   . GLY A 1 499 ? 138.095 109.052 145.703 1.00 215.52 ?  499  GLY A O   1 
ATOM   2914 N N   . GLU A 1 500 ? 137.102 107.244 144.835 1.00 232.84 ?  500  GLU A N   1 
ATOM   2915 C CA  . GLU A 1 500 ? 137.221 106.470 146.064 1.00 232.84 ?  500  GLU A CA  1 
ATOM   2916 C C   . GLU A 1 500 ? 138.648 106.009 146.255 1.00 232.84 ?  500  GLU A C   1 
ATOM   2917 O O   . GLU A 1 500 ? 139.124 105.914 147.381 1.00 232.84 ?  500  GLU A O   1 
ATOM   2918 C CB  . GLU A 1 500 ? 136.266 105.276 146.067 1.00 232.84 ?  500  GLU A CB  1 
ATOM   2919 C CG  . GLU A 1 500 ? 134.790 105.638 146.029 1.00 232.84 ?  500  GLU A CG  1 
ATOM   2920 C CD  . GLU A 1 500 ? 134.257 106.137 147.356 1.00 232.84 ?  500  GLU A CD  1 
ATOM   2921 O OE1 . GLU A 1 500 ? 134.975 106.051 148.370 1.00 232.84 ?  500  GLU A OE1 1 
ATOM   2922 O OE2 . GLU A 1 500 ? 133.108 106.620 147.385 1.00 232.84 -1 500  GLU A OE2 1 
ATOM   2923 N N   . ILE A 1 501 ? 139.341 105.722 145.161 1.00 224.81 ?  501  ILE A N   1 
ATOM   2924 C CA  . ILE A 1 501 ? 140.745 105.350 145.255 1.00 224.81 ?  501  ILE A CA  1 
ATOM   2925 C C   . ILE A 1 501 ? 141.534 106.590 145.645 1.00 224.81 ?  501  ILE A C   1 
ATOM   2926 O O   . ILE A 1 501 ? 142.478 106.507 146.417 1.00 224.81 ?  501  ILE A O   1 
ATOM   2927 C CB  . ILE A 1 501 ? 141.262 104.765 143.927 1.00 224.81 ?  501  ILE A CB  1 
ATOM   2928 C CG1 . ILE A 1 501 ? 140.583 103.429 143.636 1.00 224.81 ?  501  ILE A CG1 1 
ATOM   2929 C CG2 . ILE A 1 501 ? 142.769 104.566 143.956 1.00 224.81 ?  501  ILE A CG2 1 
ATOM   2930 C CD1 . ILE A 1 501 ? 140.802 102.937 142.223 1.00 224.81 ?  501  ILE A CD1 1 
ATOM   2931 N N   . MET A 1 502 ? 141.128 107.750 145.145 1.00 231.93 ?  502  MET A N   1 
ATOM   2932 C CA  . MET A 1 502 ? 141.798 108.994 145.499 1.00 231.93 ?  502  MET A CA  1 
ATOM   2933 C C   . MET A 1 502 ? 141.580 109.305 146.963 1.00 231.93 ?  502  MET A C   1 
ATOM   2934 O O   . MET A 1 502 ? 142.445 109.874 147.612 1.00 231.93 ?  502  MET A O   1 
ATOM   2935 C CB  . MET A 1 502 ? 141.285 110.148 144.643 1.00 231.93 ?  502  MET A CB  1 
ATOM   2936 C CG  . MET A 1 502 ? 141.847 110.184 143.234 1.00 231.93 ?  502  MET A CG  1 
ATOM   2937 S SD  . MET A 1 502 ? 143.564 110.716 143.199 1.00 231.93 ?  502  MET A SD  1 
ATOM   2938 C CE  . MET A 1 502 ? 143.380 112.474 143.484 1.00 231.93 ?  502  MET A CE  1 
ATOM   2939 N N   . ALA A 1 503 ? 140.427 108.926 147.493 1.00 224.20 ?  503  ALA A N   1 
ATOM   2940 C CA  . ALA A 1 503 ? 140.138 109.157 148.900 1.00 224.20 ?  503  ALA A CA  1 
ATOM   2941 C C   . ALA A 1 503 ? 140.862 108.144 149.760 1.00 224.20 ?  503  ALA A C   1 
ATOM   2942 O O   . ALA A 1 503 ? 141.016 108.344 150.959 1.00 224.20 ?  503  ALA A O   1 
ATOM   2943 C CB  . ALA A 1 503 ? 138.646 109.089 149.145 1.00 224.20 ?  503  ALA A CB  1 
ATOM   2944 N N   . MET A 1 504 ? 141.301 107.049 149.157 1.00 242.39 ?  504  MET A N   1 
ATOM   2945 C CA  . MET A 1 504 ? 142.049 106.044 149.890 1.00 242.39 ?  504  MET A CA  1 
ATOM   2946 C C   . MET A 1 504 ? 143.515 106.423 149.867 1.00 242.39 ?  504  MET A C   1 
ATOM   2947 O O   . MET A 1 504 ? 144.249 106.128 150.806 1.00 242.39 ?  504  MET A O   1 
ATOM   2948 C CB  . MET A 1 504 ? 141.859 104.675 149.246 1.00 242.39 ?  504  MET A CB  1 
ATOM   2949 C CG  . MET A 1 504 ? 141.513 103.562 150.218 1.00 242.39 ?  504  MET A CG  1 
ATOM   2950 S SD  . MET A 1 504 ? 141.114 102.024 149.366 1.00 242.39 ?  504  MET A SD  1 
ATOM   2951 C CE  . MET A 1 504 ? 141.414 102.493 147.666 1.00 242.39 ?  504  MET A CE  1 
ATOM   2952 N N   . LEU A 1 505 ? 143.945 107.081 148.797 1.00 248.74 ?  505  LEU A N   1 
ATOM   2953 C CA  . LEU A 1 505 ? 145.338 107.493 148.677 1.00 248.74 ?  505  LEU A CA  1 
ATOM   2954 C C   . LEU A 1 505 ? 145.557 108.770 149.452 1.00 248.74 ?  505  LEU A C   1 
ATOM   2955 O O   . LEU A 1 505 ? 146.632 108.988 150.004 1.00 248.74 ?  505  LEU A O   1 
ATOM   2956 C CB  . LEU A 1 505 ? 145.704 107.715 147.214 1.00 248.74 ?  505  LEU A CB  1 
ATOM   2957 C CG  . LEU A 1 505 ? 145.760 106.484 146.313 1.00 248.74 ?  505  LEU A CG  1 
ATOM   2958 C CD1 . LEU A 1 505 ? 145.938 106.906 144.864 1.00 248.74 ?  505  LEU A CD1 1 
ATOM   2959 C CD2 . LEU A 1 505 ? 146.872 105.546 146.750 1.00 248.74 ?  505  LEU A CD2 1 
ATOM   2960 N N   . PHE A 1 506 ? 144.543 109.624 149.491 1.00 246.98 ?  506  PHE A N   1 
ATOM   2961 C CA  . PHE A 1 506 ? 144.638 110.871 150.235 1.00 246.98 ?  506  PHE A CA  1 
ATOM   2962 C C   . PHE A 1 506 ? 143.516 110.929 151.253 1.00 246.98 ?  506  PHE A C   1 
ATOM   2963 O O   . PHE A 1 506 ? 142.498 111.574 151.017 1.00 246.98 ?  506  PHE A O   1 
ATOM   2964 C CB  . PHE A 1 506 ? 144.544 112.060 149.285 1.00 246.98 ?  506  PHE A CB  1 
ATOM   2965 C CG  . PHE A 1 506 ? 145.572 112.041 148.195 1.00 246.98 ?  506  PHE A CG  1 
ATOM   2966 C CD1 . PHE A 1 506 ? 146.904 112.275 148.483 1.00 246.98 ?  506  PHE A CD1 1 
ATOM   2967 C CD2 . PHE A 1 506 ? 145.210 111.778 146.887 1.00 246.98 ?  506  PHE A CD2 1 
ATOM   2968 C CE1 . PHE A 1 506 ? 147.857 112.253 147.484 1.00 246.98 ?  506  PHE A CE1 1 
ATOM   2969 C CE2 . PHE A 1 506 ? 146.157 111.753 145.884 1.00 246.98 ?  506  PHE A CE2 1 
ATOM   2970 C CZ  . PHE A 1 506 ? 147.482 111.992 146.182 1.00 246.98 ?  506  PHE A CZ  1 
ATOM   2971 N N   . PRO A 1 507 ? 143.695 110.257 152.399 1.00 253.49 ?  507  PRO A N   1 
ATOM   2972 C CA  . PRO A 1 507 ? 142.616 110.203 153.387 1.00 253.49 ?  507  PRO A CA  1 
ATOM   2973 C C   . PRO A 1 507 ? 142.390 111.530 154.096 1.00 253.49 ?  507  PRO A C   1 
ATOM   2974 O O   . PRO A 1 507 ? 141.282 111.785 154.562 1.00 253.49 ?  507  PRO A O   1 
ATOM   2975 C CB  . PRO A 1 507 ? 143.109 109.151 154.389 1.00 253.49 ?  507  PRO A CB  1 
ATOM   2976 C CG  . PRO A 1 507 ? 144.279 108.481 153.745 1.00 253.49 ?  507  PRO A CG  1 
ATOM   2977 C CD  . PRO A 1 507 ? 144.880 109.516 152.852 1.00 253.49 ?  507  PRO A CD  1 
ATOM   2978 N N   . ASP A 1 508 ? 143.418 112.365 154.176 1.00 263.43 ?  508  ASP A N   1 
ATOM   2979 C CA  . ASP A 1 508 ? 143.300 113.641 154.867 1.00 263.43 ?  508  ASP A CA  1 
ATOM   2980 C C   . ASP A 1 508 ? 143.151 114.794 153.891 1.00 263.43 ?  508  ASP A C   1 
ATOM   2981 O O   . ASP A 1 508 ? 143.115 115.953 154.297 1.00 263.43 ?  508  ASP A O   1 
ATOM   2982 C CB  . ASP A 1 508 ? 144.513 113.864 155.765 1.00 263.43 ?  508  ASP A CB  1 
ATOM   2983 C CG  . ASP A 1 508 ? 145.348 112.611 155.932 1.00 263.43 ?  508  ASP A CG  1 
ATOM   2984 O OD1 . ASP A 1 508 ? 145.044 111.810 156.840 1.00 263.43 ?  508  ASP A OD1 1 
ATOM   2985 O OD2 . ASP A 1 508 ? 146.305 112.424 155.151 1.00 263.43 -1 508  ASP A OD2 1 
ATOM   2986 N N   . GLY A 1 509 ? 143.064 114.484 152.604 1.00 262.92 ?  509  GLY A N   1 
ATOM   2987 C CA  . GLY A 1 509 ? 142.884 115.520 151.607 1.00 262.92 ?  509  GLY A CA  1 
ATOM   2988 C C   . GLY A 1 509 ? 144.182 115.930 150.954 1.00 262.92 ?  509  GLY A C   1 
ATOM   2989 O O   . GLY A 1 509 ? 145.245 115.424 151.305 1.00 262.92 ?  509  GLY A O   1 
ATOM   2990 N N   . ILE A 1 510 ? 144.104 116.843 149.994 1.00 274.31 ?  510  ILE A N   1 
ATOM   2991 C CA  . ILE A 1 510 ? 145.303 117.321 149.324 1.00 274.31 ?  510  ILE A CA  1 
ATOM   2992 C C   . ILE A 1 510 ? 145.446 118.825 149.476 1.00 274.31 ?  510  ILE A C   1 
ATOM   2993 O O   . ILE A 1 510 ? 144.598 119.582 149.011 1.00 274.31 ?  510  ILE A O   1 
ATOM   2994 C CB  . ILE A 1 510 ? 145.307 116.967 147.826 1.00 274.31 ?  510  ILE A CB  1 
ATOM   2995 C CG1 . ILE A 1 510 ? 143.971 116.367 147.400 1.00 274.31 ?  510  ILE A CG1 1 
ATOM   2996 C CG2 . ILE A 1 510 ? 146.432 115.996 147.513 1.00 274.31 ?  510  ILE A CG2 1 
ATOM   2997 C CD1 . ILE A 1 510 ? 144.060 115.600 146.101 1.00 274.31 ?  510  ILE A CD1 1 
ATOM   2998 N N   . LEU A 1 511 ? 146.520 119.261 150.123 1.00 278.35 ?  511  LEU A N   1 
ATOM   2999 C CA  . LEU A 1 511 ? 146.749 120.687 150.305 1.00 278.35 ?  511  LEU A CA  1 
ATOM   3000 C C   . LEU A 1 511 ? 147.217 121.348 149.021 1.00 278.35 ?  511  LEU A C   1 
ATOM   3001 O O   . LEU A 1 511 ? 148.087 120.824 148.329 1.00 278.35 ?  511  LEU A O   1 
ATOM   3002 C CB  . LEU A 1 511 ? 147.756 120.943 151.426 1.00 278.35 ?  511  LEU A CB  1 
ATOM   3003 C CG  . LEU A 1 511 ? 147.606 122.280 152.158 1.00 278.35 ?  511  LEU A CG  1 
ATOM   3004 C CD1 . LEU A 1 511 ? 147.580 122.070 153.662 1.00 278.35 ?  511  LEU A CD1 1 
ATOM   3005 C CD2 . LEU A 1 511 ? 148.715 123.246 151.773 1.00 278.35 ?  511  LEU A CD2 1 
ATOM   3006 N N   . PHE A 1 512 ? 146.643 122.499 148.702 1.00 288.57 ?  512  PHE A N   1 
ATOM   3007 C CA  . PHE A 1 512 ? 147.040 123.220 147.505 1.00 288.57 ?  512  PHE A CA  1 
ATOM   3008 C C   . PHE A 1 512 ? 147.868 124.426 147.905 1.00 288.57 ?  512  PHE A C   1 
ATOM   3009 O O   . PHE A 1 512 ? 149.060 124.302 148.180 1.00 288.57 ?  512  PHE A O   1 
ATOM   3010 C CB  . PHE A 1 512 ? 145.804 123.665 146.735 1.00 288.57 ?  512  PHE A CB  1 
ATOM   3011 C CG  . PHE A 1 512 ? 146.083 124.075 145.320 1.00 288.57 ?  512  PHE A CG  1 
ATOM   3012 C CD1 . PHE A 1 512 ? 147.249 123.684 144.686 1.00 288.57 ?  512  PHE A CD1 1 
ATOM   3013 C CD2 . PHE A 1 512 ? 145.177 124.856 144.627 1.00 288.57 ?  512  PHE A CD2 1 
ATOM   3014 C CE1 . PHE A 1 512 ? 147.508 124.067 143.388 1.00 288.57 ?  512  PHE A CE1 1 
ATOM   3015 C CE2 . PHE A 1 512 ? 145.430 125.243 143.328 1.00 288.57 ?  512  PHE A CE2 1 
ATOM   3016 C CZ  . PHE A 1 512 ? 146.598 124.850 142.710 1.00 288.57 ?  512  PHE A CZ  1 
ATOM   3017 N N   . ASP A 1 513 ? 147.246 125.598 147.935 1.00 309.02 ?  513  ASP A N   1 
ATOM   3018 C CA  . ASP A 1 513 ? 147.953 126.793 148.366 1.00 309.02 ?  513  ASP A CA  1 
ATOM   3019 C C   . ASP A 1 513 ? 147.954 126.817 149.877 1.00 309.02 ?  513  ASP A C   1 
ATOM   3020 O O   . ASP A 1 513 ? 149.001 126.674 150.504 1.00 309.02 ?  513  ASP A O   1 
ATOM   3021 C CB  . ASP A 1 513 ? 147.271 128.045 147.821 1.00 309.02 ?  513  ASP A CB  1 
ATOM   3022 C CG  . ASP A 1 513 ? 146.420 127.759 146.604 1.00 309.02 ?  513  ASP A CG  1 
ATOM   3023 O OD1 . ASP A 1 513 ? 146.981 127.706 145.490 1.00 309.02 ?  513  ASP A OD1 1 
ATOM   3024 O OD2 . ASP A 1 513 ? 145.193 127.589 146.760 1.00 309.02 -1 513  ASP A OD2 1 
ATOM   3025 N N   . ASP A 1 514 ? 146.781 126.992 150.468 1.00 319.74 ?  514  ASP A N   1 
ATOM   3026 C CA  . ASP A 1 514 ? 146.668 126.981 151.918 1.00 319.74 ?  514  ASP A CA  1 
ATOM   3027 C C   . ASP A 1 514 ? 145.399 126.242 152.263 1.00 319.74 ?  514  ASP A C   1 
ATOM   3028 O O   . ASP A 1 514 ? 144.907 126.329 153.387 1.00 319.74 ?  514  ASP A O   1 
ATOM   3029 C CB  . ASP A 1 514 ? 146.599 128.405 152.461 1.00 319.74 ?  514  ASP A CB  1 
ATOM   3030 C CG  . ASP A 1 514 ? 146.013 129.382 151.462 1.00 319.74 ?  514  ASP A CG  1 
ATOM   3031 O OD1 . ASP A 1 514 ? 144.776 129.389 151.288 1.00 319.74 ?  514  ASP A OD1 1 
ATOM   3032 O OD2 . ASP A 1 514 ? 146.790 130.143 150.848 1.00 319.74 -1 514  ASP A OD2 1 
ATOM   3033 N N   . ILE A 1 515 ? 144.858 125.513 151.295 1.00 292.48 ?  515  ILE A N   1 
ATOM   3034 C CA  . ILE A 1 515 ? 143.597 124.825 151.515 1.00 292.48 ?  515  ILE A CA  1 
ATOM   3035 C C   . ILE A 1 515 ? 143.730 123.321 151.383 1.00 292.48 ?  515  ILE A C   1 
ATOM   3036 O O   . ILE A 1 515 ? 144.194 122.829 150.360 1.00 292.48 ?  515  ILE A O   1 
ATOM   3037 C CB  . ILE A 1 515 ? 142.533 125.305 150.512 1.00 292.48 ?  515  ILE A CB  1 
ATOM   3038 C CG1 . ILE A 1 515 ? 143.139 126.318 149.538 1.00 292.48 ?  515  ILE A CG1 1 
ATOM   3039 C CG2 . ILE A 1 515 ? 141.342 125.902 151.244 1.00 292.48 ?  515  ILE A CG2 1 
ATOM   3040 C CD1 . ILE A 1 515 ? 142.265 127.526 149.289 1.00 292.48 ?  515  ILE A CD1 1 
ATOM   3041 N N   . ILE A 1 516 ? 143.319 122.586 152.410 1.00 282.09 ?  516  ILE A N   1 
ATOM   3042 C CA  . ILE A 1 516 ? 143.343 121.132 152.328 1.00 282.09 ?  516  ILE A CA  1 
ATOM   3043 C C   . ILE A 1 516 ? 142.073 120.647 151.662 1.00 282.09 ?  516  ILE A C   1 
ATOM   3044 O O   . ILE A 1 516 ? 141.079 120.378 152.332 1.00 282.09 ?  516  ILE A O   1 
ATOM   3045 C CB  . ILE A 1 516 ? 143.454 120.479 153.712 1.00 282.09 ?  516  ILE A CB  1 
ATOM   3046 C CG1 . ILE A 1 516 ? 143.864 121.517 154.757 1.00 282.09 ?  516  ILE A CG1 1 
ATOM   3047 C CG2 . ILE A 1 516 ? 144.442 119.324 153.673 1.00 282.09 ?  516  ILE A CG2 1 
ATOM   3048 C CD1 . ILE A 1 516 ? 144.422 120.914 156.027 1.00 282.09 ?  516  ILE A CD1 1 
ATOM   3049 N N   . TYR A 1 517 ? 142.099 120.539 150.341 1.00 286.12 ?  517  TYR A N   1 
ATOM   3050 C CA  . TYR A 1 517 ? 140.925 120.099 149.607 1.00 286.12 ?  517  TYR A CA  1 
ATOM   3051 C C   . TYR A 1 517 ? 140.629 118.641 149.890 1.00 286.12 ?  517  TYR A C   1 
ATOM   3052 O O   . TYR A 1 517 ? 141.443 117.774 149.591 1.00 286.12 ?  517  TYR A O   1 
ATOM   3053 C CB  . TYR A 1 517 ? 141.144 120.283 148.110 1.00 286.12 ?  517  TYR A CB  1 
ATOM   3054 C CG  . TYR A 1 517 ? 141.120 121.716 147.644 1.00 286.12 ?  517  TYR A CG  1 
ATOM   3055 C CD1 . TYR A 1 517 ? 139.930 122.327 147.283 1.00 286.12 ?  517  TYR A CD1 1 
ATOM   3056 C CD2 . TYR A 1 517 ? 142.289 122.453 147.550 1.00 286.12 ?  517  TYR A CD2 1 
ATOM   3057 C CE1 . TYR A 1 517 ? 139.905 123.636 146.847 1.00 286.12 ?  517  TYR A CE1 1 
ATOM   3058 C CE2 . TYR A 1 517 ? 142.273 123.759 147.113 1.00 286.12 ?  517  TYR A CE2 1 
ATOM   3059 C CZ  . TYR A 1 517 ? 141.079 124.345 146.766 1.00 286.12 ?  517  TYR A CZ  1 
ATOM   3060 O OH  . TYR A 1 517 ? 141.065 125.647 146.337 1.00 286.12 ?  517  TYR A OH  1 
ATOM   3061 N N   . LYS A 1 518 ? 139.462 118.363 150.454 1.00 248.57 ?  518  LYS A N   1 
ATOM   3062 C CA  . LYS A 1 518 ? 139.078 116.984 150.715 1.00 248.57 ?  518  LYS A CA  1 
ATOM   3063 C C   . LYS A 1 518 ? 138.534 116.342 149.452 1.00 248.57 ?  518  LYS A C   1 
ATOM   3064 O O   . LYS A 1 518 ? 137.899 117.008 148.637 1.00 248.57 ?  518  LYS A O   1 
ATOM   3065 C CB  . LYS A 1 518 ? 138.045 116.916 151.834 1.00 248.57 ?  518  LYS A CB  1 
ATOM   3066 C CG  . LYS A 1 518 ? 138.646 116.678 153.206 1.00 248.57 ?  518  LYS A CG  1 
ATOM   3067 C CD  . LYS A 1 518 ? 139.150 115.252 153.343 1.00 248.57 ?  518  LYS A CD  1 
ATOM   3068 C CE  . LYS A 1 518 ? 139.478 114.931 154.790 1.00 248.57 ?  518  LYS A CE  1 
ATOM   3069 N NZ  . LYS A 1 518 ? 140.157 116.076 155.456 1.00 248.57 1  518  LYS A NZ  1 
ATOM   3070 N N   . ILE A 1 519 ? 138.783 115.049 149.284 1.00 216.28 ?  519  ILE A N   1 
ATOM   3071 C CA  . ILE A 1 519 ? 138.330 114.351 148.087 1.00 216.28 ?  519  ILE A CA  1 
ATOM   3072 C C   . ILE A 1 519 ? 136.841 114.090 148.127 1.00 216.28 ?  519  ILE A C   1 
ATOM   3073 O O   . ILE A 1 519 ? 136.330 113.552 149.107 1.00 216.28 ?  519  ILE A O   1 
ATOM   3074 C CB  . ILE A 1 519 ? 139.057 113.009 147.915 1.00 216.28 ?  519  ILE A CB  1 
ATOM   3075 C CG1 . ILE A 1 519 ? 140.543 113.171 148.224 1.00 216.28 ?  519  ILE A CG1 1 
ATOM   3076 C CG2 . ILE A 1 519 ? 138.863 112.469 146.509 1.00 216.28 ?  519  ILE A CG2 1 
ATOM   3077 C CD1 . ILE A 1 519 ? 141.403 113.246 146.986 1.00 216.28 ?  519  ILE A CD1 1 
ATOM   3078 N N   . LEU A 1 520 ? 136.136 114.480 147.074 1.00 225.65 ?  520  LEU A N   1 
ATOM   3079 C CA  . LEU A 1 520 ? 134.710 114.213 146.995 1.00 225.65 ?  520  LEU A CA  1 
ATOM   3080 C C   . LEU A 1 520 ? 134.520 113.212 145.880 1.00 225.65 ?  520  LEU A C   1 
ATOM   3081 O O   . LEU A 1 520 ? 134.485 113.590 144.715 1.00 225.65 ?  520  LEU A O   1 
ATOM   3082 C CB  . LEU A 1 520 ? 133.949 115.494 146.674 1.00 225.65 ?  520  LEU A CB  1 
ATOM   3083 C CG  . LEU A 1 520 ? 132.508 115.623 147.166 1.00 225.65 ?  520  LEU A CG  1 
ATOM   3084 C CD1 . LEU A 1 520 ? 132.242 114.681 148.329 1.00 225.65 ?  520  LEU A CD1 1 
ATOM   3085 C CD2 . LEU A 1 520 ? 132.242 117.063 147.568 1.00 225.65 ?  520  LEU A CD2 1 
ATOM   3086 N N   . PRO A 1 521 ? 134.400 111.925 146.226 1.00 240.84 ?  521  PRO A N   1 
ATOM   3087 C CA  . PRO A 1 521 ? 134.295 110.896 145.192 1.00 240.84 ?  521  PRO A CA  1 
ATOM   3088 C C   . PRO A 1 521 ? 133.092 111.091 144.280 1.00 240.84 ?  521  PRO A C   1 
ATOM   3089 O O   . PRO A 1 521 ? 133.160 110.730 143.108 1.00 240.84 ?  521  PRO A O   1 
ATOM   3090 C CB  . PRO A 1 521 ? 134.151 109.615 146.003 1.00 240.84 ?  521  PRO A CB  1 
ATOM   3091 C CG  . PRO A 1 521 ? 134.772 109.922 147.320 1.00 240.84 ?  521  PRO A CG  1 
ATOM   3092 C CD  . PRO A 1 521 ? 134.393 111.345 147.577 1.00 240.84 ?  521  PRO A CD  1 
ATOM   3093 N N   . GLY A 1 522 ? 132.010 111.658 144.799 1.00 248.08 ?  522  GLY A N   1 
ATOM   3094 C CA  . GLY A 1 522 ? 130.830 111.902 143.995 1.00 248.08 ?  522  GLY A CA  1 
ATOM   3095 C C   . GLY A 1 522 ? 131.079 112.948 142.942 1.00 248.08 ?  522  GLY A C   1 
ATOM   3096 O O   . GLY A 1 522 ? 130.483 112.904 141.873 1.00 248.08 ?  522  GLY A O   1 
ATOM   3097 N N   . GLY A 1 523 ? 131.953 113.901 143.238 1.00 250.29 ?  523  GLY A N   1 
ATOM   3098 C CA  . GLY A 1 523 ? 132.298 114.913 142.262 1.00 250.29 ?  523  GLY A CA  1 
ATOM   3099 C C   . GLY A 1 523 ? 133.010 114.268 141.102 1.00 250.29 ?  523  GLY A C   1 
ATOM   3100 O O   . GLY A 1 523 ? 132.726 114.584 139.955 1.00 250.29 ?  523  GLY A O   1 
ATOM   3101 N N   . TYR A 1 524 ? 133.919 113.346 141.393 1.00 229.92 ?  524  TYR A N   1 
ATOM   3102 C CA  . TYR A 1 524 ? 134.629 112.632 140.345 1.00 229.92 ?  524  TYR A CA  1 
ATOM   3103 C C   . TYR A 1 524 ? 133.643 111.865 139.487 1.00 229.92 ?  524  TYR A C   1 
ATOM   3104 O O   . TYR A 1 524 ? 133.830 111.752 138.282 1.00 229.92 ?  524  TYR A O   1 
ATOM   3105 C CB  . TYR A 1 524 ? 135.629 111.657 140.957 1.00 229.92 ?  524  TYR A CB  1 
ATOM   3106 C CG  . TYR A 1 524 ? 136.898 112.283 141.481 1.00 229.92 ?  524  TYR A CG  1 
ATOM   3107 C CD1 . TYR A 1 524 ? 136.891 113.053 142.633 1.00 229.92 ?  524  TYR A CD1 1 
ATOM   3108 C CD2 . TYR A 1 524 ? 138.108 112.086 140.835 1.00 229.92 ?  524  TYR A CD2 1 
ATOM   3109 C CE1 . TYR A 1 524 ? 138.048 113.622 143.118 1.00 229.92 ?  524  TYR A CE1 1 
ATOM   3110 C CE2 . TYR A 1 524 ? 139.272 112.652 141.314 1.00 229.92 ?  524  TYR A CE2 1 
ATOM   3111 C CZ  . TYR A 1 524 ? 139.233 113.418 142.457 1.00 229.92 ?  524  TYR A CZ  1 
ATOM   3112 O OH  . TYR A 1 524 ? 140.384 113.985 142.942 1.00 229.92 ?  524  TYR A OH  1 
ATOM   3113 N N   . ALA A 1 525 ? 132.592 111.333 140.102 1.00 256.65 ?  525  ALA A N   1 
ATOM   3114 C CA  . ALA A 1 525 ? 131.578 110.591 139.364 1.00 256.65 ?  525  ALA A CA  1 
ATOM   3115 C C   . ALA A 1 525 ? 130.862 111.455 138.349 1.00 256.65 ?  525  ALA A C   1 
ATOM   3116 O O   . ALA A 1 525 ? 130.654 111.031 137.222 1.00 256.65 ?  525  ALA A O   1 
ATOM   3117 C CB  . ALA A 1 525 ? 130.583 109.972 140.318 1.00 256.65 ?  525  ALA A CB  1 
ATOM   3118 N N   . VAL A 1 526 ? 130.477 112.665 138.738 1.00 270.30 ?  526  VAL A N   1 
ATOM   3119 C CA  . VAL A 1 526 ? 129.836 113.581 137.801 1.00 270.30 ?  526  VAL A CA  1 
ATOM   3120 C C   . VAL A 1 526 ? 130.732 113.800 136.596 1.00 270.30 ?  526  VAL A C   1 
ATOM   3121 O O   . VAL A 1 526 ? 130.281 113.721 135.455 1.00 270.30 ?  526  VAL A O   1 
ATOM   3122 C CB  . VAL A 1 526 ? 129.509 114.932 138.460 1.00 270.30 ?  526  VAL A CB  1 
ATOM   3123 C CG1 . VAL A 1 526 ? 128.701 115.806 137.518 1.00 270.30 ?  526  VAL A CG1 1 
ATOM   3124 C CG2 . VAL A 1 526 ? 128.750 114.719 139.756 1.00 270.30 ?  526  VAL A CG2 1 
ATOM   3125 N N   . ILE A 1 527 ? 132.011 114.056 136.843 1.00 254.86 ?  527  ILE A N   1 
ATOM   3126 C CA  . ILE A 1 527 ? 132.956 114.270 135.755 1.00 254.86 ?  527  ILE A CA  1 
ATOM   3127 C C   . ILE A 1 527 ? 133.073 113.034 134.880 1.00 254.86 ?  527  ILE A C   1 
ATOM   3128 O O   . ILE A 1 527 ? 133.041 113.137 133.659 1.00 254.86 ?  527  ILE A O   1 
ATOM   3129 C CB  . ILE A 1 527 ? 134.341 114.649 136.301 1.00 254.86 ?  527  ILE A CB  1 
ATOM   3130 C CG1 . ILE A 1 527 ? 134.198 115.618 137.467 1.00 254.86 ?  527  ILE A CG1 1 
ATOM   3131 C CG2 . ILE A 1 527 ? 135.198 115.271 135.219 1.00 254.86 ?  527  ILE A CG2 1 
ATOM   3132 C CD1 . ILE A 1 527 ? 134.646 117.022 137.158 1.00 254.86 ?  527  ILE A CD1 1 
ATOM   3133 N N   . GLY A 1 528 ? 133.197 111.865 135.495 1.00 250.40 ?  528  GLY A N   1 
ATOM   3134 C CA  . GLY A 1 528 ? 133.304 110.631 134.742 1.00 250.40 ?  528  GLY A CA  1 
ATOM   3135 C C   . GLY A 1 528 ? 132.094 110.370 133.883 1.00 250.40 ?  528  GLY A C   1 
ATOM   3136 O O   . GLY A 1 528 ? 132.225 109.897 132.760 1.00 250.40 ?  528  GLY A O   1 
ATOM   3137 N N   . ALA A 1 529 ? 130.910 110.669 134.401 1.00 232.85 ?  529  ALA A N   1 
ATOM   3138 C CA  . ALA A 1 529 ? 129.683 110.477 133.645 1.00 232.85 ?  529  ALA A CA  1 
ATOM   3139 C C   . ALA A 1 529 ? 129.731 111.315 132.398 1.00 232.85 ?  529  ALA A C   1 
ATOM   3140 O O   . ALA A 1 529 ? 129.560 110.799 131.302 1.00 232.85 ?  529  ALA A O   1 
ATOM   3141 C CB  . ALA A 1 529 ? 128.488 110.859 134.490 1.00 232.85 ?  529  ALA A CB  1 
ATOM   3142 N N   . ALA A 1 530 ? 129.994 112.606 132.557 1.00 253.14 ?  530  ALA A N   1 
ATOM   3143 C CA  . ALA A 1 530 ? 130.083 113.506 131.418 1.00 253.14 ?  530  ALA A CA  1 
ATOM   3144 C C   . ALA A 1 530 ? 131.154 113.093 130.428 1.00 253.14 ?  530  ALA A C   1 
ATOM   3145 O O   . ALA A 1 530 ? 130.981 113.251 129.226 1.00 253.14 ?  530  ALA A O   1 
ATOM   3146 C CB  . ALA A 1 530 ? 130.350 114.913 131.901 1.00 253.14 ?  530  ALA A CB  1 
ATOM   3147 N N   . ALA A 1 531 ? 132.266 112.571 130.924 1.00 261.07 ?  531  ALA A N   1 
ATOM   3148 C CA  . ALA A 1 531 ? 133.359 112.185 130.048 1.00 261.07 ?  531  ALA A CA  1 
ATOM   3149 C C   . ALA A 1 531 ? 133.034 110.962 129.205 1.00 261.07 ?  531  ALA A C   1 
ATOM   3150 O O   . ALA A 1 531 ? 133.251 110.977 128.001 1.00 261.07 ?  531  ALA A O   1 
ATOM   3151 C CB  . ALA A 1 531 ? 134.627 111.967 130.850 1.00 261.07 ?  531  ALA A CB  1 
ATOM   3152 N N   . LEU A 1 532 ? 132.512 109.904 129.818 1.00 256.25 ?  532  LEU A N   1 
ATOM   3153 C CA  . LEU A 1 532 ? 132.245 108.680 129.070 1.00 256.25 ?  532  LEU A CA  1 
ATOM   3154 C C   . LEU A 1 532 ? 131.076 108.864 128.128 1.00 256.25 ?  532  LEU A C   1 
ATOM   3155 O O   . LEU A 1 532 ? 131.079 108.337 127.022 1.00 256.25 ?  532  LEU A O   1 
ATOM   3156 C CB  . LEU A 1 532 ? 131.996 107.485 129.993 1.00 256.25 ?  532  LEU A CB  1 
ATOM   3157 C CG  . LEU A 1 532 ? 132.899 106.265 129.777 1.00 256.25 ?  532  LEU A CG  1 
ATOM   3158 C CD1 . LEU A 1 532 ? 132.991 105.394 131.018 1.00 256.25 ?  532  LEU A CD1 1 
ATOM   3159 C CD2 . LEU A 1 532 ? 132.466 105.433 128.586 1.00 256.25 ?  532  LEU A CD2 1 
ATOM   3160 N N   . THR A 1 533 ? 130.077 109.623 128.556 1.00 240.29 ?  533  THR A N   1 
ATOM   3161 C CA  . THR A 1 533 ? 128.921 109.866 127.709 1.00 240.29 ?  533  THR A CA  1 
ATOM   3162 C C   . THR A 1 533 ? 129.242 110.901 126.645 1.00 240.29 ?  533  THR A C   1 
ATOM   3163 O O   . THR A 1 533 ? 128.488 111.060 125.694 1.00 240.29 ?  533  THR A O   1 
ATOM   3164 C CB  . THR A 1 533 ? 127.668 110.235 128.532 1.00 240.29 ?  533  THR A CB  1 
ATOM   3165 O OG1 . THR A 1 533 ? 126.491 109.922 127.779 1.00 240.29 ?  533  THR A OG1 1 
ATOM   3166 C CG2 . THR A 1 533 ? 127.657 111.696 128.893 1.00 240.29 ?  533  THR A CG2 1 
ATOM   3167 N N   . GLY A 1 534 ? 130.370 111.587 126.782 1.00 242.01 ?  534  GLY A N   1 
ATOM   3168 C CA  . GLY A 1 534 ? 130.788 112.548 125.779 1.00 242.01 ?  534  GLY A CA  1 
ATOM   3169 C C   . GLY A 1 534 ? 131.778 111.908 124.840 1.00 242.01 ?  534  GLY A C   1 
ATOM   3170 O O   . GLY A 1 534 ? 132.055 112.439 123.776 1.00 242.01 ?  534  GLY A O   1 
ATOM   3171 N N   . ALA A 1 535 ? 132.323 110.766 125.228 1.00 218.20 ?  535  ALA A N   1 
ATOM   3172 C CA  . ALA A 1 535 ? 133.244 110.044 124.370 1.00 218.20 ?  535  ALA A CA  1 
ATOM   3173 C C   . ALA A 1 535 ? 132.445 109.114 123.487 1.00 218.20 ?  535  ALA A C   1 
ATOM   3174 O O   . ALA A 1 535 ? 132.827 108.836 122.358 1.00 218.20 ?  535  ALA A O   1 
ATOM   3175 C CB  . ALA A 1 535 ? 134.210 109.245 125.214 1.00 218.20 ?  535  ALA A CB  1 
ATOM   3176 N N   . VAL A 1 536 ? 131.331 108.620 124.003 1.00 228.69 ?  536  VAL A N   1 
ATOM   3177 C CA  . VAL A 1 536 ? 130.487 107.725 123.231 1.00 228.69 ?  536  VAL A CA  1 
ATOM   3178 C C   . VAL A 1 536 ? 129.708 108.526 122.199 1.00 228.69 ?  536  VAL A C   1 
ATOM   3179 O O   . VAL A 1 536 ? 129.556 108.095 121.059 1.00 228.69 ?  536  VAL A O   1 
ATOM   3180 C CB  . VAL A 1 536 ? 129.561 106.913 124.163 1.00 228.69 ?  536  VAL A CB  1 
ATOM   3181 C CG1 . VAL A 1 536 ? 128.177 106.714 123.567 1.00 228.69 ?  536  VAL A CG1 1 
ATOM   3182 C CG2 . VAL A 1 536 ? 130.197 105.579 124.507 1.00 228.69 ?  536  VAL A CG2 1 
ATOM   3183 N N   . SER A 1 537 ? 129.254 109.716 122.575 1.00 244.47 ?  537  SER A N   1 
ATOM   3184 C CA  . SER A 1 537 ? 128.462 110.532 121.667 1.00 244.47 ?  537  SER A CA  1 
ATOM   3185 C C   . SER A 1 537 ? 129.294 111.569 120.945 1.00 244.47 ?  537  SER A C   1 
ATOM   3186 O O   . SER A 1 537 ? 128.758 112.322 120.137 1.00 244.47 ?  537  SER A O   1 
ATOM   3187 C CB  . SER A 1 537 ? 127.355 111.231 122.438 1.00 244.47 ?  537  SER A CB  1 
ATOM   3188 O OG  . SER A 1 537 ? 127.895 112.172 123.339 1.00 244.47 ?  537  SER A OG  1 
ATOM   3189 N N   . HIS A 1 538 ? 130.592 111.615 121.228 1.00 246.50 ?  538  HIS A N   1 
ATOM   3190 C CA  . HIS A 1 538 ? 131.486 112.598 120.612 1.00 246.50 ?  538  HIS A CA  1 
ATOM   3191 C C   . HIS A 1 538 ? 130.988 114.020 120.799 1.00 246.50 ?  538  HIS A C   1 
ATOM   3192 O O   . HIS A 1 538 ? 131.010 114.814 119.864 1.00 246.50 ?  538  HIS A O   1 
ATOM   3193 C CB  . HIS A 1 538 ? 131.727 112.294 119.135 1.00 246.50 ?  538  HIS A CB  1 
ATOM   3194 C CG  . HIS A 1 538 ? 132.685 111.171 118.898 1.00 246.50 ?  538  HIS A CG  1 
ATOM   3195 N ND1 . HIS A 1 538 ? 133.062 110.771 117.635 1.00 246.50 ?  538  HIS A ND1 1 
ATOM   3196 C CD2 . HIS A 1 538 ? 133.342 110.363 119.761 1.00 246.50 ?  538  HIS A CD2 1 
ATOM   3197 C CE1 . HIS A 1 538 ? 133.911 109.764 117.732 1.00 246.50 ?  538  HIS A CE1 1 
ATOM   3198 N NE2 . HIS A 1 538 ? 134.095 109.494 119.011 1.00 246.50 ?  538  HIS A NE2 1 
ATOM   3199 N N   . THR A 1 539 ? 130.547 114.350 122.009 1.00 247.03 ?  539  THR A N   1 
ATOM   3200 C CA  . THR A 1 539 ? 130.063 115.692 122.293 1.00 247.03 ?  539  THR A CA  1 
ATOM   3201 C C   . THR A 1 539 ? 130.722 116.261 123.524 1.00 247.03 ?  539  THR A C   1 
ATOM   3202 O O   . THR A 1 539 ? 131.123 115.525 124.416 1.00 247.03 ?  539  THR A O   1 
ATOM   3203 C CB  . THR A 1 539 ? 128.555 115.714 122.562 1.00 247.03 ?  539  THR A CB  1 
ATOM   3204 O OG1 . THR A 1 539 ? 128.245 114.781 123.599 1.00 247.03 ?  539  THR A OG1 1 
ATOM   3205 C CG2 . THR A 1 539 ? 127.787 115.364 121.322 1.00 247.03 ?  539  THR A CG2 1 
ATOM   3206 N N   . VAL A 1 540 ? 130.821 117.580 123.584 1.00 231.76 ?  540  VAL A N   1 
ATOM   3207 C CA  . VAL A 1 540 ? 131.414 118.226 124.738 1.00 231.76 ?  540  VAL A CA  1 
ATOM   3208 C C   . VAL A 1 540 ? 130.329 118.973 125.489 1.00 231.76 ?  540  VAL A C   1 
ATOM   3209 O O   . VAL A 1 540 ? 130.611 119.699 126.438 1.00 231.76 ?  540  VAL A O   1 
ATOM   3210 C CB  . VAL A 1 540 ? 132.521 119.200 124.309 1.00 231.76 ?  540  VAL A CB  1 
ATOM   3211 C CG1 . VAL A 1 540 ? 133.862 118.486 124.259 1.00 231.76 ?  540  VAL A CG1 1 
ATOM   3212 C CG2 . VAL A 1 540 ? 132.193 119.812 122.957 1.00 231.76 ?  540  VAL A CG2 1 
ATOM   3213 N N   . SER A 1 541 ? 129.081 118.789 125.072 1.00 248.46 ?  541  SER A N   1 
ATOM   3214 C CA  . SER A 1 541 ? 127.964 119.474 125.710 1.00 248.46 ?  541  SER A CA  1 
ATOM   3215 C C   . SER A 1 541 ? 127.462 118.681 126.887 1.00 248.46 ?  541  SER A C   1 
ATOM   3216 O O   . SER A 1 541 ? 126.561 119.119 127.597 1.00 248.46 ?  541  SER A O   1 
ATOM   3217 C CB  . SER A 1 541 ? 126.835 119.654 124.714 1.00 248.46 ?  541  SER A CB  1 
ATOM   3218 O OG  . SER A 1 541 ? 126.820 118.583 123.792 1.00 248.46 ?  541  SER A OG  1 
ATOM   3219 N N   . THR A 1 542 ? 128.041 117.509 127.102 1.00 250.86 ?  542  THR A N   1 
ATOM   3220 C CA  . THR A 1 542 ? 127.654 116.683 128.230 1.00 250.86 ?  542  THR A CA  1 
ATOM   3221 C C   . THR A 1 542 ? 128.109 117.343 129.508 1.00 250.86 ?  542  THR A C   1 
ATOM   3222 O O   . THR A 1 542 ? 127.516 117.131 130.561 1.00 250.86 ?  542  THR A O   1 
ATOM   3223 C CB  . THR A 1 542 ? 128.267 115.292 128.106 1.00 250.86 ?  542  THR A CB  1 
ATOM   3224 O OG1 . THR A 1 542 ? 129.692 115.408 128.033 1.00 250.86 ?  542  THR A OG1 1 
ATOM   3225 C CG2 . THR A 1 542 ? 127.762 114.629 126.847 1.00 250.86 ?  542  THR A CG2 1 
ATOM   3226 N N   . ALA A 1 543 ? 129.158 118.152 129.426 1.00 235.53 ?  543  ALA A N   1 
ATOM   3227 C CA  . ALA A 1 543 ? 129.613 118.890 130.589 1.00 235.53 ?  543  ALA A CA  1 
ATOM   3228 C C   . ALA A 1 543 ? 128.514 119.834 131.028 1.00 235.53 ?  543  ALA A C   1 
ATOM   3229 O O   . ALA A 1 543 ? 128.193 119.897 132.205 1.00 235.53 ?  543  ALA A O   1 
ATOM   3230 C CB  . ALA A 1 543 ? 130.874 119.663 130.261 1.00 235.53 ?  543  ALA A CB  1 
ATOM   3231 N N   . VAL A 1 544 ? 127.924 120.559 130.084 1.00 243.13 ?  544  VAL A N   1 
ATOM   3232 C CA  . VAL A 1 544 ? 126.844 121.490 130.406 1.00 243.13 ?  544  VAL A CA  1 
ATOM   3233 C C   . VAL A 1 544 ? 125.616 120.776 130.943 1.00 243.13 ?  544  VAL A C   1 
ATOM   3234 O O   . VAL A 1 544 ? 124.967 121.268 131.864 1.00 243.13 ?  544  VAL A O   1 
ATOM   3235 C CB  . VAL A 1 544 ? 126.449 122.343 129.191 1.00 243.13 ?  544  VAL A CB  1 
ATOM   3236 C CG1 . VAL A 1 544 ? 125.966 123.709 129.645 1.00 243.13 ?  544  VAL A CG1 1 
ATOM   3237 C CG2 . VAL A 1 544 ? 127.627 122.485 128.242 1.00 243.13 ?  544  VAL A CG2 1 
ATOM   3238 N N   . ILE A 1 545 ? 125.288 119.620 130.377 1.00 258.02 ?  545  ILE A N   1 
ATOM   3239 C CA  . ILE A 1 545 ? 124.166 118.845 130.888 1.00 258.02 ?  545  ILE A CA  1 
ATOM   3240 C C   . ILE A 1 545 ? 124.430 118.535 132.349 1.00 258.02 ?  545  ILE A C   1 
ATOM   3241 O O   . ILE A 1 545 ? 123.561 118.725 133.196 1.00 258.02 ?  545  ILE A O   1 
ATOM   3242 C CB  . ILE A 1 545 ? 123.970 117.539 130.097 1.00 258.02 ?  545  ILE A CB  1 
ATOM   3243 C CG1 . ILE A 1 545 ? 123.480 117.843 128.684 1.00 258.02 ?  545  ILE A CG1 1 
ATOM   3244 C CG2 . ILE A 1 545 ? 122.989 116.613 130.800 1.00 258.02 ?  545  ILE A CG2 1 
ATOM   3245 C CD1 . ILE A 1 545 ? 123.909 116.820 127.659 1.00 258.02 ?  545  ILE A CD1 1 
ATOM   3246 N N   . CYS A 1 546 ? 125.641 118.091 132.654 1.00 261.36 ?  546  CYS A N   1 
ATOM   3247 C CA  . CYS A 1 546 ? 125.994 117.767 134.026 1.00 261.36 ?  546  CYS A CA  1 
ATOM   3248 C C   . CYS A 1 546 ? 125.982 118.988 134.930 1.00 261.36 ?  546  CYS A C   1 
ATOM   3249 O O   . CYS A 1 546 ? 125.521 118.909 136.058 1.00 261.36 ?  546  CYS A O   1 
ATOM   3250 C CB  . CYS A 1 546 ? 127.362 117.101 134.074 1.00 261.36 ?  546  CYS A CB  1 
ATOM   3251 S SG  . CYS A 1 546 ? 127.319 115.303 133.974 1.00 261.36 ?  546  CYS A SG  1 
ATOM   3252 N N   . PHE A 1 547 ? 126.482 120.118 134.442 1.00 243.82 ?  547  PHE A N   1 
ATOM   3253 C CA  . PHE A 1 547 ? 126.496 121.343 135.237 1.00 243.82 ?  547  PHE A CA  1 
ATOM   3254 C C   . PHE A 1 547 ? 125.098 121.708 135.688 1.00 243.82 ?  547  PHE A C   1 
ATOM   3255 O O   . PHE A 1 547 ? 124.894 122.109 136.827 1.00 243.82 ?  547  PHE A O   1 
ATOM   3256 C CB  . PHE A 1 547 ? 127.056 122.510 134.431 1.00 243.82 ?  547  PHE A CB  1 
ATOM   3257 C CG  . PHE A 1 547 ? 128.516 122.399 134.130 1.00 243.82 ?  547  PHE A CG  1 
ATOM   3258 C CD1 . PHE A 1 547 ? 129.371 121.746 134.996 1.00 243.82 ?  547  PHE A CD1 1 
ATOM   3259 C CD2 . PHE A 1 547 ? 129.034 122.956 132.974 1.00 243.82 ?  547  PHE A CD2 1 
ATOM   3260 C CE1 . PHE A 1 547 ? 130.716 121.645 134.711 1.00 243.82 ?  547  PHE A CE1 1 
ATOM   3261 C CE2 . PHE A 1 547 ? 130.377 122.855 132.681 1.00 243.82 ?  547  PHE A CE2 1 
ATOM   3262 C CZ  . PHE A 1 547 ? 131.218 122.195 133.549 1.00 243.82 ?  547  PHE A CZ  1 
ATOM   3263 N N   . GLU A 1 548 ? 124.130 121.584 134.790 1.00 251.54 ?  548  GLU A N   1 
ATOM   3264 C CA  . GLU A 1 548 ? 122.763 121.949 135.121 1.00 251.54 ?  548  GLU A CA  1 
ATOM   3265 C C   . GLU A 1 548 ? 122.084 120.895 135.971 1.00 251.54 ?  548  GLU A C   1 
ATOM   3266 O O   . GLU A 1 548 ? 121.199 121.208 136.759 1.00 251.54 ?  548  GLU A O   1 
ATOM   3267 C CB  . GLU A 1 548 ? 121.960 122.196 133.850 1.00 251.54 ?  548  GLU A CB  1 
ATOM   3268 C CG  . GLU A 1 548 ? 122.066 123.618 133.331 1.00 251.54 ?  548  GLU A CG  1 
ATOM   3269 C CD  . GLU A 1 548 ? 121.729 123.722 131.860 1.00 251.54 ?  548  GLU A CD  1 
ATOM   3270 O OE1 . GLU A 1 548 ? 122.640 123.532 131.028 1.00 251.54 ?  548  GLU A OE1 1 
ATOM   3271 O OE2 . GLU A 1 548 ? 120.551 123.985 131.537 1.00 251.54 -1 548  GLU A OE2 1 
ATOM   3272 N N   . LEU A 1 549 ? 122.495 119.644 135.819 1.00 243.78 ?  549  LEU A N   1 
ATOM   3273 C CA  . LEU A 1 549 ? 121.921 118.572 136.618 1.00 243.78 ?  549  LEU A CA  1 
ATOM   3274 C C   . LEU A 1 549 ? 122.489 118.604 138.024 1.00 243.78 ?  549  LEU A C   1 
ATOM   3275 O O   . LEU A 1 549 ? 121.868 118.104 138.956 1.00 243.78 ?  549  LEU A O   1 
ATOM   3276 C CB  . LEU A 1 549 ? 122.200 117.216 135.972 1.00 243.78 ?  549  LEU A CB  1 
ATOM   3277 C CG  . LEU A 1 549 ? 121.132 116.701 135.011 1.00 243.78 ?  549  LEU A CG  1 
ATOM   3278 C CD1 . LEU A 1 549 ? 121.509 115.331 134.470 1.00 243.78 ?  549  LEU A CD1 1 
ATOM   3279 C CD2 . LEU A 1 549 ? 119.783 116.654 135.707 1.00 243.78 ?  549  LEU A CD2 1 
ATOM   3280 N N   . THR A 1 550 ? 123.671 119.186 138.182 1.00 250.34 ?  550  THR A N   1 
ATOM   3281 C CA  . THR A 1 550 ? 124.317 119.239 139.484 1.00 250.34 ?  550  THR A CA  1 
ATOM   3282 C C   . THR A 1 550 ? 124.645 120.679 139.838 1.00 250.34 ?  550  THR A C   1 
ATOM   3283 O O   . THR A 1 550 ? 123.837 121.575 139.597 1.00 250.34 ?  550  THR A O   1 
ATOM   3284 C CB  . THR A 1 550 ? 125.621 118.419 139.475 1.00 250.34 ?  550  THR A CB  1 
ATOM   3285 O OG1 . THR A 1 550 ? 126.584 119.044 138.616 1.00 250.34 ?  550  THR A OG1 1 
ATOM   3286 C CG2 . THR A 1 550 ? 125.364 117.006 138.974 1.00 250.34 ?  550  THR A CG2 1 
ATOM   3287 N N   . GLY A 1 551 ? 125.816 120.913 140.423 1.00 251.09 ?  551  GLY A N   1 
ATOM   3288 C CA  . GLY A 1 551 ? 126.243 122.271 140.715 1.00 251.09 ?  551  GLY A CA  1 
ATOM   3289 C C   . GLY A 1 551 ? 127.150 122.697 139.583 1.00 251.09 ?  551  GLY A C   1 
ATOM   3290 O O   . GLY A 1 551 ? 127.329 121.946 138.627 1.00 251.09 ?  551  GLY A O   1 
ATOM   3291 N N   . GLN A 1 552 ? 127.748 123.878 139.672 1.00 247.59 ?  552  GLN A N   1 
ATOM   3292 C CA  . GLN A 1 552 ? 128.547 124.363 138.549 1.00 247.59 ?  552  GLN A CA  1 
ATOM   3293 C C   . GLN A 1 552 ? 129.999 124.659 138.865 1.00 247.59 ?  552  GLN A C   1 
ATOM   3294 O O   . GLN A 1 552 ? 130.879 123.889 138.489 1.00 247.59 ?  552  GLN A O   1 
ATOM   3295 C CB  . GLN A 1 552 ? 127.904 125.615 137.950 1.00 247.59 ?  552  GLN A CB  1 
ATOM   3296 C CG  . GLN A 1 552 ? 127.129 125.367 136.671 1.00 247.59 ?  552  GLN A CG  1 
ATOM   3297 C CD  . GLN A 1 552 ? 127.567 126.277 135.545 1.00 247.59 ?  552  GLN A CD  1 
ATOM   3298 O OE1 . GLN A 1 552 ? 127.450 125.933 134.369 1.00 247.59 ?  552  GLN A OE1 1 
ATOM   3299 N NE2 . GLN A 1 552 ? 128.078 127.449 135.899 1.00 247.59 ?  552  GLN A NE2 1 
ATOM   3300 N N   . ILE A 1 553 ? 130.259 125.769 139.547 1.00 216.24 ?  553  ILE A N   1 
ATOM   3301 C CA  . ILE A 1 553 ? 131.638 126.190 139.811 1.00 216.24 ?  553  ILE A CA  1 
ATOM   3302 C C   . ILE A 1 553 ? 132.544 125.178 140.491 1.00 216.24 ?  553  ILE A C   1 
ATOM   3303 O O   . ILE A 1 553 ? 132.053 124.232 141.112 1.00 216.24 ?  553  ILE A O   1 
ATOM   3304 C CB  . ILE A 1 553 ? 131.675 127.512 140.602 1.00 216.24 ?  553  ILE A CB  1 
ATOM   3305 C CG1 . ILE A 1 553 ? 130.284 127.850 141.140 1.00 216.24 ?  553  ILE A CG1 1 
ATOM   3306 C CG2 . ILE A 1 553 ? 132.182 128.640 139.718 1.00 216.24 ?  553  ILE A CG2 1 
ATOM   3307 C CD1 . ILE A 1 553 ? 129.710 129.132 140.577 1.00 216.24 ?  553  ILE A CD1 1 
ATOM   3308 N N   . ALA A 1 554 ? 133.859 125.374 140.371 1.00 188.20 ?  554  ALA A N   1 
ATOM   3309 C CA  . ALA A 1 554 ? 134.851 124.458 140.960 1.00 188.20 ?  554  ALA A CA  1 
ATOM   3310 C C   . ALA A 1 554 ? 134.855 123.082 140.321 1.00 188.20 ?  554  ALA A C   1 
ATOM   3311 O O   . ALA A 1 554 ? 135.573 122.193 140.773 1.00 188.20 ?  554  ALA A O   1 
ATOM   3312 C CB  . ALA A 1 554 ? 134.720 124.366 142.477 1.00 188.20 ?  554  ALA A CB  1 
ATOM   3313 N N   . HIS A 1 555 ? 134.068 122.903 139.268 1.00 232.88 ?  555  HIS A N   1 
ATOM   3314 C CA  . HIS A 1 555 ? 134.048 121.635 138.557 1.00 232.88 ?  555  HIS A CA  1 
ATOM   3315 C C   . HIS A 1 555 ? 133.896 121.926 137.086 1.00 232.88 ?  555  HIS A C   1 
ATOM   3316 O O   . HIS A 1 555 ? 133.737 121.016 136.287 1.00 232.88 ?  555  HIS A O   1 
ATOM   3317 C CB  . HIS A 1 555 ? 132.919 120.735 139.045 1.00 232.88 ?  555  HIS A CB  1 
ATOM   3318 C CG  . HIS A 1 555 ? 133.393 119.570 139.853 1.00 232.88 ?  555  HIS A CG  1 
ATOM   3319 N ND1 . HIS A 1 555 ? 134.710 119.416 140.230 1.00 232.88 ?  555  HIS A ND1 1 
ATOM   3320 C CD2 . HIS A 1 555 ? 132.730 118.503 140.356 1.00 232.88 ?  555  HIS A CD2 1 
ATOM   3321 C CE1 . HIS A 1 555 ? 134.837 118.306 140.932 1.00 232.88 ?  555  HIS A CE1 1 
ATOM   3322 N NE2 . HIS A 1 555 ? 133.651 117.733 141.024 1.00 232.88 ?  555  HIS A NE2 1 
ATOM   3323 N N   . ILE A 1 556 ? 133.947 123.202 136.726 1.00 212.91 ?  556  ILE A N   1 
ATOM   3324 C CA  . ILE A 1 556 ? 133.860 123.573 135.326 1.00 212.91 ?  556  ILE A CA  1 
ATOM   3325 C C   . ILE A 1 556 ? 135.133 123.157 134.625 1.00 212.91 ?  556  ILE A C   1 
ATOM   3326 O O   . ILE A 1 556 ? 135.095 122.355 133.701 1.00 212.91 ?  556  ILE A O   1 
ATOM   3327 C CB  . ILE A 1 556 ? 133.651 125.083 135.149 1.00 212.91 ?  556  ILE A CB  1 
ATOM   3328 C CG1 . ILE A 1 556 ? 132.486 125.562 136.009 1.00 212.91 ?  556  ILE A CG1 1 
ATOM   3329 C CG2 . ILE A 1 556 ? 133.391 125.420 133.690 1.00 212.91 ?  556  ILE A CG2 1 
ATOM   3330 C CD1 . ILE A 1 556 ? 131.230 125.834 135.216 1.00 212.91 ?  556  ILE A CD1 1 
ATOM   3331 N N   . LEU A 1 557 ? 136.264 123.693 135.066 1.00 222.33 ?  557  LEU A N   1 
ATOM   3332 C CA  . LEU A 1 557 ? 137.546 123.320 134.477 1.00 222.33 ?  557  LEU A CA  1 
ATOM   3333 C C   . LEU A 1 557 ? 137.828 121.818 134.566 1.00 222.33 ?  557  LEU A C   1 
ATOM   3334 O O   . LEU A 1 557 ? 138.168 121.211 133.558 1.00 222.33 ?  557  LEU A O   1 
ATOM   3335 C CB  . LEU A 1 557 ? 138.697 124.152 135.060 1.00 222.33 ?  557  LEU A CB  1 
ATOM   3336 C CG  . LEU A 1 557 ? 139.745 124.672 134.079 1.00 222.33 ?  557  LEU A CG  1 
ATOM   3337 C CD1 . LEU A 1 557 ? 141.040 123.888 134.218 1.00 222.33 ?  557  LEU A CD1 1 
ATOM   3338 C CD2 . LEU A 1 557 ? 139.226 124.619 132.650 1.00 222.33 ?  557  LEU A CD2 1 
ATOM   3339 N N   . PRO A 1 558 ? 137.688 121.205 135.759 1.00 213.78 ?  558  PRO A N   1 
ATOM   3340 C CA  . PRO A 1 558 ? 137.878 119.752 135.777 1.00 213.78 ?  558  PRO A CA  1 
ATOM   3341 C C   . PRO A 1 558 ? 137.060 119.037 134.709 1.00 213.78 ?  558  PRO A C   1 
ATOM   3342 O O   . PRO A 1 558 ? 137.618 118.240 133.959 1.00 213.78 ?  558  PRO A O   1 
ATOM   3343 C CB  . PRO A 1 558 ? 137.362 119.359 137.150 1.00 213.78 ?  558  PRO A CB  1 
ATOM   3344 C CG  . PRO A 1 558 ? 137.622 120.535 138.004 1.00 213.78 ?  558  PRO A CG  1 
ATOM   3345 C CD  . PRO A 1 558 ? 137.542 121.747 137.125 1.00 213.78 ?  558  PRO A CD  1 
ATOM   3346 N N   . MET A 1 559 ? 135.762 119.316 134.635 1.00 225.71 ?  559  MET A N   1 
ATOM   3347 C CA  . MET A 1 559 ? 134.905 118.644 133.667 1.00 225.71 ?  559  MET A CA  1 
ATOM   3348 C C   . MET A 1 559 ? 135.298 118.957 132.241 1.00 225.71 ?  559  MET A C   1 
ATOM   3349 O O   . MET A 1 559 ? 135.410 118.058 131.426 1.00 225.71 ?  559  MET A O   1 
ATOM   3350 C CB  . MET A 1 559 ? 133.435 118.987 133.881 1.00 225.71 ?  559  MET A CB  1 
ATOM   3351 C CG  . MET A 1 559 ? 132.496 117.831 133.586 1.00 225.71 ?  559  MET A CG  1 
ATOM   3352 S SD  . MET A 1 559 ? 130.870 118.022 134.333 1.00 225.71 ?  559  MET A SD  1 
ATOM   3353 C CE  . MET A 1 559 ? 131.299 118.244 136.056 1.00 225.71 ?  559  MET A CE  1 
ATOM   3354 N N   . MET A 1 560 ? 135.513 120.227 131.935 1.00 228.96 ?  560  MET A N   1 
ATOM   3355 C CA  . MET A 1 560 ? 135.919 120.611 130.595 1.00 228.96 ?  560  MET A CA  1 
ATOM   3356 C C   . MET A 1 560 ? 137.129 119.815 130.160 1.00 228.96 ?  560  MET A C   1 
ATOM   3357 O O   . MET A 1 560 ? 137.107 119.186 129.112 1.00 228.96 ?  560  MET A O   1 
ATOM   3358 C CB  . MET A 1 560 ? 136.234 122.099 130.538 1.00 228.96 ?  560  MET A CB  1 
ATOM   3359 C CG  . MET A 1 560 ? 135.470 122.852 129.465 1.00 228.96 ?  560  MET A CG  1 
ATOM   3360 S SD  . MET A 1 560 ? 134.301 124.029 130.165 1.00 228.96 ?  560  MET A SD  1 
ATOM   3361 C CE  . MET A 1 560 ? 132.748 123.269 129.699 1.00 228.96 ?  560  MET A CE  1 
ATOM   3362 N N   . VAL A 1 561 ? 138.181 119.828 130.969 1.00 228.93 ?  561  VAL A N   1 
ATOM   3363 C CA  . VAL A 1 561 ? 139.391 119.090 130.636 1.00 228.93 ?  561  VAL A CA  1 
ATOM   3364 C C   . VAL A 1 561 ? 139.057 117.636 130.375 1.00 228.93 ?  561  VAL A C   1 
ATOM   3365 O O   . VAL A 1 561 ? 139.382 117.106 129.319 1.00 228.93 ?  561  VAL A O   1 
ATOM   3366 C CB  . VAL A 1 561 ? 140.452 119.202 131.748 1.00 228.93 ?  561  VAL A CB  1 
ATOM   3367 C CG1 . VAL A 1 561 ? 141.604 118.242 131.498 1.00 228.93 ?  561  VAL A CG1 1 
ATOM   3368 C CG2 . VAL A 1 561 ? 140.969 120.627 131.838 1.00 228.93 ?  561  VAL A CG2 1 
ATOM   3369 N N   . ALA A 1 562 ? 138.379 116.995 131.318 1.00 228.46 ?  562  ALA A N   1 
ATOM   3370 C CA  . ALA A 1 562 ? 138.025 115.592 131.162 1.00 228.46 ?  562  ALA A CA  1 
ATOM   3371 C C   . ALA A 1 562 ? 137.242 115.305 129.887 1.00 228.46 ?  562  ALA A C   1 
ATOM   3372 O O   . ALA A 1 562 ? 137.631 114.445 129.111 1.00 228.46 ?  562  ALA A O   1 
ATOM   3373 C CB  . ALA A 1 562 ? 137.252 115.114 132.368 1.00 228.46 ?  562  ALA A CB  1 
ATOM   3374 N N   . VAL A 1 563 ? 136.143 116.015 129.666 1.00 239.08 ?  563  VAL A N   1 
ATOM   3375 C CA  . VAL A 1 563 ? 135.312 115.764 128.493 1.00 239.08 ?  563  VAL A CA  1 
ATOM   3376 C C   . VAL A 1 563 ? 136.063 116.023 127.191 1.00 239.08 ?  563  VAL A C   1 
ATOM   3377 O O   . VAL A 1 563 ? 135.938 115.255 126.245 1.00 239.08 ?  563  VAL A O   1 
ATOM   3378 C CB  . VAL A 1 563 ? 133.994 116.564 128.536 1.00 239.08 ?  563  VAL A CB  1 
ATOM   3379 C CG1 . VAL A 1 563 ? 133.087 116.162 127.387 1.00 239.08 ?  563  VAL A CG1 1 
ATOM   3380 C CG2 . VAL A 1 563 ? 133.273 116.315 129.849 1.00 239.08 ?  563  VAL A CG2 1 
ATOM   3381 N N   . ILE A 1 564 ? 136.859 117.084 127.140 1.00 243.29 ?  564  ILE A N   1 
ATOM   3382 C CA  . ILE A 1 564 ? 137.649 117.368 125.946 1.00 243.29 ?  564  ILE A CA  1 
ATOM   3383 C C   . ILE A 1 564 ? 138.644 116.246 125.689 1.00 243.29 ?  564  ILE A C   1 
ATOM   3384 O O   . ILE A 1 564 ? 138.745 115.749 124.573 1.00 243.29 ?  564  ILE A O   1 
ATOM   3385 C CB  . ILE A 1 564 ? 138.370 118.726 126.051 1.00 243.29 ?  564  ILE A CB  1 
ATOM   3386 C CG1 . ILE A 1 564 ? 137.378 119.866 125.829 1.00 243.29 ?  564  ILE A CG1 1 
ATOM   3387 C CG2 . ILE A 1 564 ? 139.506 118.831 125.046 1.00 243.29 ?  564  ILE A CG2 1 
ATOM   3388 C CD1 . ILE A 1 564 ? 137.890 121.213 126.284 1.00 243.29 ?  564  ILE A CD1 1 
ATOM   3389 N N   . LEU A 1 565 ? 139.354 115.817 126.726 1.00 267.30 ?  565  LEU A N   1 
ATOM   3390 C CA  . LEU A 1 565 ? 140.310 114.727 126.578 1.00 267.30 ?  565  LEU A CA  1 
ATOM   3391 C C   . LEU A 1 565 ? 139.612 113.446 126.165 1.00 267.30 ?  565  LEU A C   1 
ATOM   3392 O O   . LEU A 1 565 ? 140.122 112.706 125.334 1.00 267.30 ?  565  LEU A O   1 
ATOM   3393 C CB  . LEU A 1 565 ? 141.087 114.516 127.874 1.00 267.30 ?  565  LEU A CB  1 
ATOM   3394 C CG  . LEU A 1 565 ? 142.135 115.580 128.189 1.00 267.30 ?  565  LEU A CG  1 
ATOM   3395 C CD1 . LEU A 1 565 ? 143.049 115.117 129.307 1.00 267.30 ?  565  LEU A CD1 1 
ATOM   3396 C CD2 . LEU A 1 565 ? 142.939 115.934 126.950 1.00 267.30 ?  565  LEU A CD2 1 
ATOM   3397 N N   . ALA A 1 566 ? 138.443 113.183 126.733 1.00 262.27 ?  566  ALA A N   1 
ATOM   3398 C CA  . ALA A 1 566 ? 137.681 112.000 126.366 1.00 262.27 ?  566  ALA A CA  1 
ATOM   3399 C C   . ALA A 1 566 ? 137.317 112.056 124.904 1.00 262.27 ?  566  ALA A C   1 
ATOM   3400 O O   . ALA A 1 566 ? 137.557 111.107 124.169 1.00 262.27 ?  566  ALA A O   1 
ATOM   3401 C CB  . ALA A 1 566 ? 136.430 111.903 127.208 1.00 262.27 ?  566  ALA A CB  1 
ATOM   3402 N N   . ASN A 1 567 ? 136.741 113.170 124.475 1.00 256.31 ?  567  ASN A N   1 
ATOM   3403 C CA  . ASN A 1 567 ? 136.368 113.330 123.081 1.00 256.31 ?  567  ASN A CA  1 
ATOM   3404 C C   . ASN A 1 567 ? 137.565 113.068 122.199 1.00 256.31 ?  567  ASN A C   1 
ATOM   3405 O O   . ASN A 1 567 ? 137.476 112.297 121.260 1.00 256.31 ?  567  ASN A O   1 
ATOM   3406 C CB  . ASN A 1 567 ? 135.852 114.741 122.827 1.00 256.31 ?  567  ASN A CB  1 
ATOM   3407 C CG  . ASN A 1 567 ? 134.360 114.857 123.008 1.00 256.31 ?  567  ASN A CG  1 
ATOM   3408 O OD1 . ASN A 1 567 ? 133.640 115.186 122.072 1.00 256.31 ?  567  ASN A OD1 1 
ATOM   3409 N ND2 . ASN A 1 567 ? 133.889 114.600 124.219 1.00 256.31 ?  567  ASN A ND2 1 
ATOM   3410 N N   . MET A 1 568 ? 138.690 113.701 122.503 1.00 259.23 ?  568  MET A N   1 
ATOM   3411 C CA  . MET A 1 568 ? 139.894 113.531 121.702 1.00 259.23 ?  568  MET A CA  1 
ATOM   3412 C C   . MET A 1 568 ? 140.298 112.074 121.554 1.00 259.23 ?  568  MET A C   1 
ATOM   3413 O O   . MET A 1 568 ? 140.435 111.576 120.440 1.00 259.23 ?  568  MET A O   1 
ATOM   3414 C CB  . MET A 1 568 ? 141.045 114.327 122.308 1.00 259.23 ?  568  MET A CB  1 
ATOM   3415 C CG  . MET A 1 568 ? 140.985 115.816 122.021 1.00 259.23 ?  568  MET A CG  1 
ATOM   3416 S SD  . MET A 1 568 ? 142.272 116.710 122.907 1.00 259.23 ?  568  MET A SD  1 
ATOM   3417 C CE  . MET A 1 568 ? 143.487 115.411 123.116 1.00 259.23 ?  568  MET A CE  1 
ATOM   3418 N N   . VAL A 1 569 ? 140.492 111.387 122.672 1.00 227.12 ?  569  VAL A N   1 
ATOM   3419 C CA  . VAL A 1 569 ? 140.893 109.988 122.626 1.00 227.12 ?  569  VAL A CA  1 
ATOM   3420 C C   . VAL A 1 569 ? 139.879 109.158 121.851 1.00 227.12 ?  569  VAL A C   1 
ATOM   3421 O O   . VAL A 1 569 ? 140.248 108.393 120.962 1.00 227.12 ?  569  VAL A O   1 
ATOM   3422 C CB  . VAL A 1 569 ? 141.092 109.409 124.040 1.00 227.12 ?  569  VAL A CB  1 
ATOM   3423 C CG1 . VAL A 1 569 ? 141.501 107.949 123.967 1.00 227.12 ?  569  VAL A CG1 1 
ATOM   3424 C CG2 . VAL A 1 569 ? 142.146 110.205 124.790 1.00 227.12 ?  569  VAL A CG2 1 
ATOM   3425 N N   . ALA A 1 570 ? 138.600 109.322 122.160 1.00 244.26 ?  570  ALA A N   1 
ATOM   3426 C CA  . ALA A 1 570 ? 137.565 108.539 121.495 1.00 244.26 ?  570  ALA A CA  1 
ATOM   3427 C C   . ALA A 1 570 ? 137.468 108.832 120.009 1.00 244.26 ?  570  ALA A C   1 
ATOM   3428 O O   . ALA A 1 570 ? 137.310 107.917 119.212 1.00 244.26 ?  570  ALA A O   1 
ATOM   3429 C CB  . ALA A 1 570 ? 136.227 108.765 122.158 1.00 244.26 ?  570  ALA A CB  1 
ATOM   3430 N N   . GLN A 1 571 ? 137.561 110.100 119.631 1.00 249.88 ?  571  GLN A N   1 
ATOM   3431 C CA  . GLN A 1 571 ? 137.473 110.473 118.227 1.00 249.88 ?  571  GLN A CA  1 
ATOM   3432 C C   . GLN A 1 571 ? 138.616 109.863 117.449 1.00 249.88 ?  571  GLN A C   1 
ATOM   3433 O O   . GLN A 1 571 ? 138.449 109.474 116.296 1.00 249.88 ?  571  GLN A O   1 
ATOM   3434 C CB  . GLN A 1 571 ? 137.497 111.990 118.070 1.00 249.88 ?  571  GLN A CB  1 
ATOM   3435 C CG  . GLN A 1 571 ? 136.136 112.619 117.837 1.00 249.88 ?  571  GLN A CG  1 
ATOM   3436 C CD  . GLN A 1 571 ? 135.916 113.853 118.685 1.00 249.88 ?  571  GLN A CD  1 
ATOM   3437 O OE1 . GLN A 1 571 ? 134.819 114.085 119.190 1.00 249.88 ?  571  GLN A OE1 1 
ATOM   3438 N NE2 . GLN A 1 571 ? 136.962 114.652 118.848 1.00 249.88 ?  571  GLN A NE2 1 
ATOM   3439 N N   . SER A 1 572 ? 139.781 109.773 118.077 1.00 280.35 ?  572  SER A N   1 
ATOM   3440 C CA  . SER A 1 572 ? 140.941 109.200 117.418 1.00 280.35 ?  572  SER A CA  1 
ATOM   3441 C C   . SER A 1 572 ? 140.815 107.698 117.251 1.00 280.35 ?  572  SER A C   1 
ATOM   3442 O O   . SER A 1 572 ? 141.441 107.119 116.367 1.00 280.35 ?  572  SER A O   1 
ATOM   3443 C CB  . SER A 1 572 ? 142.200 109.524 118.214 1.00 280.35 ?  572  SER A CB  1 
ATOM   3444 O OG  . SER A 1 572 ? 142.494 108.499 119.143 1.00 280.35 ?  572  SER A OG  1 
ATOM   3445 N N   . LEU A 1 573 ? 140.009 107.058 118.088 1.00 229.04 ?  573  LEU A N   1 
ATOM   3446 C CA  . LEU A 1 573 ? 139.902 105.606 118.037 1.00 229.04 ?  573  LEU A CA  1 
ATOM   3447 C C   . LEU A 1 573 ? 138.697 105.091 117.261 1.00 229.04 ?  573  LEU A C   1 
ATOM   3448 O O   . LEU A 1 573 ? 138.862 104.445 116.230 1.00 229.04 ?  573  LEU A O   1 
ATOM   3449 C CB  . LEU A 1 573 ? 139.910 105.030 119.449 1.00 229.04 ?  573  LEU A CB  1 
ATOM   3450 C CG  . LEU A 1 573 ? 141.184 105.243 120.263 1.00 229.04 ?  573  LEU A CG  1 
ATOM   3451 C CD1 . LEU A 1 573 ? 140.977 104.790 121.698 1.00 229.04 ?  573  LEU A CD1 1 
ATOM   3452 C CD2 . LEU A 1 573 ? 142.356 104.514 119.628 1.00 229.04 ?  573  LEU A CD2 1 
ATOM   3453 N N   . GLN A 1 574 ? 137.489 105.357 117.746 1.00 226.72 ?  574  GLN A N   1 
ATOM   3454 C CA  . GLN A 1 574 ? 136.292 104.830 117.093 1.00 226.72 ?  574  GLN A CA  1 
ATOM   3455 C C   . GLN A 1 574 ? 135.310 105.928 116.724 1.00 226.72 ?  574  GLN A C   1 
ATOM   3456 O O   . GLN A 1 574 ? 135.449 107.054 117.183 1.00 226.72 ?  574  GLN A O   1 
ATOM   3457 C CB  . GLN A 1 574 ? 135.600 103.803 118.002 1.00 226.72 ?  574  GLN A CB  1 
ATOM   3458 C CG  . GLN A 1 574 ? 136.404 102.546 118.291 1.00 226.72 ?  574  GLN A CG  1 
ATOM   3459 C CD  . GLN A 1 574 ? 136.797 101.786 117.041 1.00 226.72 ?  574  GLN A CD  1 
ATOM   3460 O OE1 . GLN A 1 574 ? 135.976 101.549 116.159 1.00 226.72 ?  574  GLN A OE1 1 
ATOM   3461 N NE2 . GLN A 1 574 ? 138.062 101.392 116.964 1.00 226.72 ?  574  GLN A NE2 1 
ATOM   3462 N N   . PRO A 1 575 ? 134.315 105.616 115.875 1.00 270.67 ?  575  PRO A N   1 
ATOM   3463 C CA  . PRO A 1 575 ? 133.279 106.613 115.579 1.00 270.67 ?  575  PRO A CA  1 
ATOM   3464 C C   . PRO A 1 575 ? 132.345 106.834 116.764 1.00 270.67 ?  575  PRO A C   1 
ATOM   3465 O O   . PRO A 1 575 ? 132.486 106.170 117.785 1.00 270.67 ?  575  PRO A O   1 
ATOM   3466 C CB  . PRO A 1 575 ? 132.497 105.969 114.436 1.00 270.67 ?  575  PRO A CB  1 
ATOM   3467 C CG  . PRO A 1 575 ? 133.448 105.021 113.801 1.00 270.67 ?  575  PRO A CG  1 
ATOM   3468 C CD  . PRO A 1 575 ? 134.278 104.489 114.927 1.00 270.67 ?  575  PRO A CD  1 
ATOM   3469 N N   . SER A 1 576 ? 131.398 107.755 116.641 1.00 286.08 ?  576  SER A N   1 
ATOM   3470 C CA  . SER A 1 576 ? 130.436 107.976 117.712 1.00 286.08 ?  576  SER A CA  1 
ATOM   3471 C C   . SER A 1 576 ? 129.431 106.847 117.690 1.00 286.08 ?  576  SER A C   1 
ATOM   3472 O O   . SER A 1 576 ? 129.318 106.144 116.697 1.00 286.08 ?  576  SER A O   1 
ATOM   3473 C CB  . SER A 1 576 ? 129.725 109.312 117.530 1.00 286.08 ?  576  SER A CB  1 
ATOM   3474 O OG  . SER A 1 576 ? 128.379 109.130 117.136 1.00 286.08 ?  576  SER A OG  1 
ATOM   3475 N N   . LEU A 1 577 ? 128.698 106.664 118.778 1.00 272.66 ?  577  LEU A N   1 
ATOM   3476 C CA  . LEU A 1 577 ? 127.695 105.616 118.826 1.00 272.66 ?  577  LEU A CA  1 
ATOM   3477 C C   . LEU A 1 577 ? 126.755 105.783 117.665 1.00 272.66 ?  577  LEU A C   1 
ATOM   3478 O O   . LEU A 1 577 ? 126.524 104.847 116.915 1.00 272.66 ?  577  LEU A O   1 
ATOM   3479 C CB  . LEU A 1 577 ? 126.904 105.679 120.130 1.00 272.66 ?  577  LEU A CB  1 
ATOM   3480 C CG  . LEU A 1 577 ? 126.693 104.372 120.893 1.00 272.66 ?  577  LEU A CG  1 
ATOM   3481 C CD1 . LEU A 1 577 ? 125.211 104.094 121.080 1.00 272.66 ?  577  LEU A CD1 1 
ATOM   3482 C CD2 . LEU A 1 577 ? 127.383 103.210 120.199 1.00 272.66 ?  577  LEU A CD2 1 
ATOM   3483 N N   . TYR A 1 578 ? 126.223 106.982 117.496 1.00 288.67 ?  578  TYR A N   1 
ATOM   3484 C CA  . TYR A 1 578 ? 125.251 107.226 116.443 1.00 288.67 ?  578  TYR A CA  1 
ATOM   3485 C C   . TYR A 1 578 ? 125.838 107.089 115.053 1.00 288.67 ?  578  TYR A C   1 
ATOM   3486 O O   . TYR A 1 578 ? 125.176 106.593 114.153 1.00 288.67 ?  578  TYR A O   1 
ATOM   3487 C CB  . TYR A 1 578 ? 124.623 108.597 116.651 1.00 288.67 ?  578  TYR A CB  1 
ATOM   3488 C CG  . TYR A 1 578 ? 124.366 108.875 118.109 1.00 288.67 ?  578  TYR A CG  1 
ATOM   3489 C CD1 . TYR A 1 578 ? 123.470 108.100 118.835 1.00 288.67 ?  578  TYR A CD1 1 
ATOM   3490 C CD2 . TYR A 1 578 ? 125.039 109.889 118.769 1.00 288.67 ?  578  TYR A CD2 1 
ATOM   3491 C CE1 . TYR A 1 578 ? 123.242 108.340 120.174 1.00 288.67 ?  578  TYR A CE1 1 
ATOM   3492 C CE2 . TYR A 1 578 ? 124.816 110.135 120.106 1.00 288.67 ?  578  TYR A CE2 1 
ATOM   3493 C CZ  . TYR A 1 578 ? 123.919 109.360 120.802 1.00 288.67 ?  578  TYR A CZ  1 
ATOM   3494 O OH  . TYR A 1 578 ? 123.706 109.610 122.133 1.00 288.67 ?  578  TYR A OH  1 
ATOM   3495 N N   . ASP A 1 579 ? 127.084 107.506 114.876 1.00 309.79 ?  579  ASP A N   1 
ATOM   3496 C CA  . ASP A 1 579 ? 127.738 107.358 113.585 1.00 309.79 ?  579  ASP A CA  1 
ATOM   3497 C C   . ASP A 1 579 ? 128.016 105.899 113.294 1.00 309.79 ?  579  ASP A C   1 
ATOM   3498 O O   . ASP A 1 579 ? 127.906 105.461 112.155 1.00 309.79 ?  579  ASP A O   1 
ATOM   3499 C CB  . ASP A 1 579 ? 129.030 108.163 113.542 1.00 309.79 ?  579  ASP A CB  1 
ATOM   3500 C CG  . ASP A 1 579 ? 128.782 109.646 113.388 1.00 309.79 ?  579  ASP A CG  1 
ATOM   3501 O OD1 . ASP A 1 579 ? 127.931 110.021 112.555 1.00 309.79 ?  579  ASP A OD1 1 
ATOM   3502 O OD2 . ASP A 1 579 ? 129.434 110.436 114.099 1.00 309.79 -1 579  ASP A OD2 1 
ATOM   3503 N N   . SER A 1 580 ? 128.364 105.136 114.319 1.00 294.72 ?  580  SER A N   1 
ATOM   3504 C CA  . SER A 1 580 ? 128.601 103.714 114.135 1.00 294.72 ?  580  SER A CA  1 
ATOM   3505 C C   . SER A 1 580 ? 127.304 102.992 113.816 1.00 294.72 ?  580  SER A C   1 
ATOM   3506 O O   . SER A 1 580 ? 127.301 102.047 113.039 1.00 294.72 ?  580  SER A O   1 
ATOM   3507 C CB  . SER A 1 580 ? 129.256 103.109 115.373 1.00 294.72 ?  580  SER A CB  1 
ATOM   3508 O OG  . SER A 1 580 ? 128.328 102.354 116.131 1.00 294.72 ?  580  SER A OG  1 
ATOM   3509 N N   . ILE A 1 581 ? 126.199 103.436 114.406 1.00 282.70 ?  581  ILE A N   1 
ATOM   3510 C CA  . ILE A 1 581 ? 124.908 102.826 114.122 1.00 282.70 ?  581  ILE A CA  1 
ATOM   3511 C C   . ILE A 1 581 ? 124.512 103.173 112.700 1.00 282.70 ?  581  ILE A C   1 
ATOM   3512 O O   . ILE A 1 581 ? 123.968 102.337 111.986 1.00 282.70 ?  581  ILE A O   1 
ATOM   3513 C CB  . ILE A 1 581 ? 123.835 103.264 115.134 1.00 282.70 ?  581  ILE A CB  1 
ATOM   3514 C CG1 . ILE A 1 581 ? 124.167 102.727 116.525 1.00 282.70 ?  581  ILE A CG1 1 
ATOM   3515 C CG2 . ILE A 1 581 ? 122.462 102.755 114.733 1.00 282.70 ?  581  ILE A CG2 1 
ATOM   3516 C CD1 . ILE A 1 581 ? 123.308 103.311 117.624 1.00 282.70 ?  581  ILE A CD1 1 
ATOM   3517 N N   . ILE A 1 582 ? 124.808 104.392 112.265 1.00 277.28 ?  582  ILE A N   1 
ATOM   3518 C CA  . ILE A 1 582 ? 124.536 104.765 110.884 1.00 277.28 ?  582  ILE A CA  1 
ATOM   3519 C C   . ILE A 1 582 ? 125.243 103.772 109.976 1.00 277.28 ?  582  ILE A C   1 
ATOM   3520 O O   . ILE A 1 582 ? 124.635 103.226 109.060 1.00 277.28 ?  582  ILE A O   1 
ATOM   3521 C CB  . ILE A 1 582 ? 125.007 106.203 110.583 1.00 277.28 ?  582  ILE A CB  1 
ATOM   3522 C CG1 . ILE A 1 582 ? 123.966 107.217 111.051 1.00 277.28 ?  582  ILE A CG1 1 
ATOM   3523 C CG2 . ILE A 1 582 ? 125.285 106.402 109.101 1.00 277.28 ?  582  ILE A CG2 1 
ATOM   3524 C CD1 . ILE A 1 582 ? 124.498 108.629 111.141 1.00 277.28 ?  582  ILE A CD1 1 
ATOM   3525 N N   . GLN A 1 583 ? 126.517 103.504 110.246 1.00 314.83 ?  583  GLN A N   1 
ATOM   3526 C CA  . GLN A 1 583 ? 127.277 102.557 109.436 1.00 314.83 ?  583  GLN A CA  1 
ATOM   3527 C C   . GLN A 1 583 ? 126.696 101.149 109.461 1.00 314.83 ?  583  GLN A C   1 
ATOM   3528 O O   . GLN A 1 583 ? 126.615 100.498 108.424 1.00 314.83 ?  583  GLN A O   1 
ATOM   3529 C CB  . GLN A 1 583 ? 128.731 102.518 109.894 1.00 314.83 ?  583  GLN A CB  1 
ATOM   3530 C CG  . GLN A 1 583 ? 129.506 103.792 109.616 1.00 314.83 ?  583  GLN A CG  1 
ATOM   3531 C CD  . GLN A 1 583 ? 130.524 104.096 110.696 1.00 314.83 ?  583  GLN A CD  1 
ATOM   3532 O OE1 . GLN A 1 583 ? 131.010 103.194 111.378 1.00 314.83 ?  583  GLN A OE1 1 
ATOM   3533 N NE2 . GLN A 1 583 ? 130.849 105.373 110.860 1.00 314.83 ?  583  GLN A NE2 1 
ATOM   3534 N N   . VAL A 1 584 ? 126.303 100.671 110.636 1.00 286.70 ?  584  VAL A N   1 
ATOM   3535 C CA  . VAL A 1 584 ? 125.702 99.343  110.747 1.00 286.70 ?  584  VAL A CA  1 
ATOM   3536 C C   . VAL A 1 584 ? 124.448 99.260  109.890 1.00 286.70 ?  584  VAL A C   1 
ATOM   3537 O O   . VAL A 1 584 ? 124.273 98.310  109.127 1.00 286.70 ?  584  VAL A O   1 
ATOM   3538 C CB  . VAL A 1 584 ? 125.353 98.993  112.210 1.00 286.70 ?  584  VAL A CB  1 
ATOM   3539 C CG1 . VAL A 1 584 ? 124.509 97.730  112.286 1.00 286.70 ?  584  VAL A CG1 1 
ATOM   3540 C CG2 . VAL A 1 584 ? 126.618 98.825  113.032 1.00 286.70 ?  584  VAL A CG2 1 
ATOM   3541 N N   . LYS A 1 585 ? 123.586 100.265 109.987 1.00 267.69 ?  585  LYS A N   1 
ATOM   3542 C CA  . LYS A 1 585 ? 122.344 100.263 109.225 1.00 267.69 ?  585  LYS A CA  1 
ATOM   3543 C C   . LYS A 1 585 ? 122.545 100.768 107.809 1.00 267.69 ?  585  LYS A C   1 
ATOM   3544 O O   . LYS A 1 585 ? 121.573 100.922 107.072 1.00 267.69 ?  585  LYS A O   1 
ATOM   3545 C CB  . LYS A 1 585 ? 121.294 101.115 109.932 1.00 267.69 ?  585  LYS A CB  1 
ATOM   3546 C CG  . LYS A 1 585 ? 121.065 100.734 111.384 1.00 267.69 ?  585  LYS A CG  1 
ATOM   3547 C CD  . LYS A 1 585 ? 119.583 100.652 111.705 1.00 267.69 ?  585  LYS A CD  1 
ATOM   3548 C CE  . LYS A 1 585 ? 119.209 101.614 112.819 1.00 267.69 ?  585  LYS A CE  1 
ATOM   3549 N NZ  . LYS A 1 585 ? 119.721 102.985 112.551 1.00 267.69 1  585  LYS A NZ  1 
ATOM   3550 N N   . LYS A 1 586 ? 123.792 101.034 107.429 1.00 276.08 ?  586  LYS A N   1 
ATOM   3551 C CA  . LYS A 1 586 ? 124.105 101.530 106.086 1.00 276.08 ?  586  LYS A CA  1 
ATOM   3552 C C   . LYS A 1 586 ? 123.208 102.687 105.695 1.00 276.08 ?  586  LYS A C   1 
ATOM   3553 O O   . LYS A 1 586 ? 122.724 102.748 104.567 1.00 276.08 ?  586  LYS A O   1 
ATOM   3554 C CB  . LYS A 1 586 ? 124.026 100.404 105.053 1.00 276.08 ?  586  LYS A CB  1 
ATOM   3555 C CG  . LYS A 1 586 ? 125.278 99.547  104.976 1.00 276.08 ?  586  LYS A CG  1 
ATOM   3556 C CD  . LYS A 1 586 ? 125.077 98.201  105.653 1.00 276.08 ?  586  LYS A CD  1 
ATOM   3557 C CE  . LYS A 1 586 ? 123.692 97.641  105.376 1.00 276.08 ?  586  LYS A CE  1 
ATOM   3558 N NZ  . LYS A 1 586 ? 122.994 97.235  106.627 1.00 276.08 1  586  LYS A NZ  1 
ATOM   3559 N N   . LEU A 1 587 ? 122.987 103.609 106.624 1.00 300.88 ?  587  LEU A N   1 
ATOM   3560 C CA  . LEU A 1 587 ? 122.129 104.749 106.352 1.00 300.88 ?  587  LEU A CA  1 
ATOM   3561 C C   . LEU A 1 587 ? 122.827 105.679 105.382 1.00 300.88 ?  587  LEU A C   1 
ATOM   3562 O O   . LEU A 1 587 ? 124.011 105.971 105.548 1.00 300.88 ?  587  LEU A O   1 
ATOM   3563 C CB  . LEU A 1 587 ? 121.783 105.480 107.649 1.00 300.88 ?  587  LEU A CB  1 
ATOM   3564 C CG  . LEU A 1 587 ? 120.697 104.830 108.504 1.00 300.88 ?  587  LEU A CG  1 
ATOM   3565 C CD1 . LEU A 1 587 ? 120.784 105.311 109.942 1.00 300.88 ?  587  LEU A CD1 1 
ATOM   3566 C CD2 . LEU A 1 587 ? 119.321 105.115 107.924 1.00 300.88 ?  587  LEU A CD2 1 
ATOM   3567 N N   . PRO A 1 588 ? 122.102 106.146 104.357 1.00 320.95 ?  588  PRO A N   1 
ATOM   3568 C CA  . PRO A 1 588 ? 122.686 107.038 103.351 1.00 320.95 ?  588  PRO A CA  1 
ATOM   3569 C C   . PRO A 1 588 ? 123.426 108.201 103.979 1.00 320.95 ?  588  PRO A C   1 
ATOM   3570 O O   . PRO A 1 588 ? 124.509 108.545 103.504 1.00 320.95 ?  588  PRO A O   1 
ATOM   3571 C CB  . PRO A 1 588 ? 121.461 107.556 102.606 1.00 320.95 ?  588  PRO A CB  1 
ATOM   3572 C CG  . PRO A 1 588 ? 120.464 106.457 102.727 1.00 320.95 ?  588  PRO A CG  1 
ATOM   3573 C CD  . PRO A 1 588 ? 120.684 105.852 104.083 1.00 320.95 ?  588  PRO A CD  1 
ATOM   3574 N N   . TYR A 1 589 ? 122.849 108.801 105.014 1.00 335.86 ?  589  TYR A N   1 
ATOM   3575 C CA  . TYR A 1 589 ? 123.489 109.910 105.705 1.00 335.86 ?  589  TYR A CA  1 
ATOM   3576 C C   . TYR A 1 589 ? 123.933 110.981 104.719 1.00 335.86 ?  589  TYR A C   1 
ATOM   3577 O O   . TYR A 1 589 ? 123.128 111.789 104.259 1.00 335.86 ?  589  TYR A O   1 
ATOM   3578 C CB  . TYR A 1 589 ? 124.667 109.400 106.538 1.00 335.86 ?  589  TYR A CB  1 
ATOM   3579 C CG  . TYR A 1 589 ? 125.245 110.408 107.498 1.00 335.86 ?  589  TYR A CG  1 
ATOM   3580 C CD1 . TYR A 1 589 ? 124.430 111.301 108.176 1.00 335.86 ?  589  TYR A CD1 1 
ATOM   3581 C CD2 . TYR A 1 589 ? 126.609 110.457 107.733 1.00 335.86 ?  589  TYR A CD2 1 
ATOM   3582 C CE1 . TYR A 1 589 ? 124.963 112.219 109.056 1.00 335.86 ?  589  TYR A CE1 1 
ATOM   3583 C CE2 . TYR A 1 589 ? 127.151 111.373 108.609 1.00 335.86 ?  589  TYR A CE2 1 
ATOM   3584 C CZ  . TYR A 1 589 ? 126.324 112.252 109.267 1.00 335.86 ?  589  TYR A CZ  1 
ATOM   3585 O OH  . TYR A 1 589 ? 126.867 113.164 110.140 1.00 335.86 ?  589  TYR A OH  1 
ATOM   3586 N N   . GLY B 1 115 ? 146.653 117.289 115.543 1.00 307.19 ?  115  GLY B N   1 
ATOM   3587 C CA  . GLY B 1 115 ? 147.755 117.599 114.652 1.00 307.19 ?  115  GLY B CA  1 
ATOM   3588 C C   . GLY B 1 115 ? 148.252 119.010 114.857 1.00 307.19 ?  115  GLY B C   1 
ATOM   3589 O O   . GLY B 1 115 ? 148.512 119.416 115.985 1.00 307.19 ?  115  GLY B O   1 
ATOM   3590 N N   . GLU B 1 116 ? 148.378 119.767 113.773 1.00 330.29 ?  116  GLU B N   1 
ATOM   3591 C CA  . GLU B 1 116 ? 148.810 121.155 113.879 1.00 330.29 ?  116  GLU B CA  1 
ATOM   3592 C C   . GLU B 1 116 ? 147.699 122.024 114.442 1.00 330.29 ?  116  GLU B C   1 
ATOM   3593 O O   . GLU B 1 116 ? 147.964 123.019 115.112 1.00 330.29 ?  116  GLU B O   1 
ATOM   3594 C CB  . GLU B 1 116 ? 149.259 121.690 112.522 1.00 330.29 ?  116  GLU B CB  1 
ATOM   3595 C CG  . GLU B 1 116 ? 150.461 122.615 112.598 1.00 330.29 ?  116  GLU B CG  1 
ATOM   3596 C CD  . GLU B 1 116 ? 150.294 123.855 111.745 1.00 330.29 ?  116  GLU B CD  1 
ATOM   3597 O OE1 . GLU B 1 116 ? 149.349 124.632 111.998 1.00 330.29 ?  116  GLU B OE1 1 
ATOM   3598 O OE2 . GLU B 1 116 ? 151.110 124.051 110.822 1.00 330.29 -1 116  GLU B OE2 1 
ATOM   3599 N N   . ASP B 1 117 ? 146.453 121.649 114.178 1.00 314.50 ?  117  ASP B N   1 
ATOM   3600 C CA  . ASP B 1 117 ? 145.328 122.401 114.712 1.00 314.50 ?  117  ASP B CA  1 
ATOM   3601 C C   . ASP B 1 117 ? 145.297 122.331 116.231 1.00 314.50 ?  117  ASP B C   1 
ATOM   3602 O O   . ASP B 1 117 ? 144.984 123.315 116.879 1.00 314.50 ?  117  ASP B O   1 
ATOM   3603 C CB  . ASP B 1 117 ? 144.003 121.925 114.109 1.00 314.50 ?  117  ASP B CB  1 
ATOM   3604 C CG  . ASP B 1 117 ? 143.602 120.540 114.581 1.00 314.50 ?  117  ASP B CG  1 
ATOM   3605 O OD1 . ASP B 1 117 ? 144.345 119.575 114.303 1.00 314.50 ?  117  ASP B OD1 1 
ATOM   3606 O OD2 . ASP B 1 117 ? 142.544 120.418 115.234 1.00 314.50 -1 117  ASP B OD2 1 
ATOM   3607 N N   . GLY B 1 118 ? 145.641 121.184 116.804 1.00 305.92 ?  118  GLY B N   1 
ATOM   3608 C CA  . GLY B 1 118 ? 145.677 121.054 118.249 1.00 305.92 ?  118  GLY B CA  1 
ATOM   3609 C C   . GLY B 1 118 ? 146.678 122.009 118.854 1.00 305.92 ?  118  GLY B C   1 
ATOM   3610 O O   . GLY B 1 118 ? 146.397 122.641 119.868 1.00 305.92 ?  118  GLY B O   1 
ATOM   3611 N N   . ILE B 1 119 ? 147.848 122.126 118.236 1.00 303.10 ?  119  ILE B N   1 
ATOM   3612 C CA  . ILE B 1 119 ? 148.854 123.063 118.720 1.00 303.10 ?  119  ILE B CA  1 
ATOM   3613 C C   . ILE B 1 119 ? 148.338 124.483 118.582 1.00 303.10 ?  119  ILE B C   1 
ATOM   3614 O O   . ILE B 1 119 ? 148.509 125.293 119.483 1.00 303.10 ?  119  ILE B O   1 
ATOM   3615 C CB  . ILE B 1 119 ? 150.180 122.924 117.953 1.00 303.10 ?  119  ILE B CB  1 
ATOM   3616 C CG1 . ILE B 1 119 ? 150.502 121.453 117.704 1.00 303.10 ?  119  ILE B CG1 1 
ATOM   3617 C CG2 . ILE B 1 119 ? 151.315 123.581 118.722 1.00 303.10 ?  119  ILE B CG2 1 
ATOM   3618 C CD1 . ILE B 1 119 ? 151.638 121.238 116.730 1.00 303.10 ?  119  ILE B CD1 1 
ATOM   3619 N N   . PHE B 1 120 ? 147.695 124.786 117.461 1.00 314.42 ?  120  PHE B N   1 
ATOM   3620 C CA  . PHE B 1 120 ? 147.129 126.113 117.261 1.00 314.42 ?  120  PHE B CA  1 
ATOM   3621 C C   . PHE B 1 120 ? 146.159 126.453 118.381 1.00 314.42 ?  120  PHE B C   1 
ATOM   3622 O O   . PHE B 1 120 ? 146.223 127.538 118.942 1.00 314.42 ?  120  PHE B O   1 
ATOM   3623 C CB  . PHE B 1 120 ? 146.449 126.201 115.893 1.00 314.42 ?  120  PHE B CB  1 
ATOM   3624 C CG  . PHE B 1 120 ? 145.539 127.384 115.734 1.00 314.42 ?  120  PHE B CG  1 
ATOM   3625 C CD1 . PHE B 1 120 ? 146.056 128.661 115.618 1.00 314.42 ?  120  PHE B CD1 1 
ATOM   3626 C CD2 . PHE B 1 120 ? 144.165 127.214 115.684 1.00 314.42 ?  120  PHE B CD2 1 
ATOM   3627 C CE1 . PHE B 1 120 ? 145.220 129.748 115.468 1.00 314.42 ?  120  PHE B CE1 1 
ATOM   3628 C CE2 . PHE B 1 120 ? 143.324 128.297 115.536 1.00 314.42 ?  120  PHE B CE2 1 
ATOM   3629 C CZ  . PHE B 1 120 ? 143.853 129.565 115.427 1.00 314.42 ?  120  PHE B CZ  1 
ATOM   3630 N N   . LEU B 1 121 ? 145.272 125.526 118.719 1.00 306.71 ?  121  LEU B N   1 
ATOM   3631 C CA  . LEU B 1 121 ? 144.294 125.774 119.769 1.00 306.71 ?  121  LEU B CA  1 
ATOM   3632 C C   . LEU B 1 121 ? 144.967 125.988 121.117 1.00 306.71 ?  121  LEU B C   1 
ATOM   3633 O O   . LEU B 1 121 ? 144.601 126.895 121.857 1.00 306.71 ?  121  LEU B O   1 
ATOM   3634 C CB  . LEU B 1 121 ? 143.288 124.626 119.855 1.00 306.71 ?  121  LEU B CB  1 
ATOM   3635 C CG  . LEU B 1 121 ? 142.548 124.254 118.573 1.00 306.71 ?  121  LEU B CG  1 
ATOM   3636 C CD1 . LEU B 1 121 ? 141.725 122.990 118.741 1.00 306.71 ?  121  LEU B CD1 1 
ATOM   3637 C CD2 . LEU B 1 121 ? 141.698 125.399 118.062 1.00 306.71 ?  121  LEU B CD2 1 
ATOM   3638 N N   . VAL B 1 122 ? 145.952 125.160 121.438 1.00 300.11 ?  122  VAL B N   1 
ATOM   3639 C CA  . VAL B 1 122 ? 146.664 125.302 122.701 1.00 300.11 ?  122  VAL B CA  1 
ATOM   3640 C C   . VAL B 1 122 ? 147.359 126.653 122.747 1.00 300.11 ?  122  VAL B C   1 
ATOM   3641 O O   . VAL B 1 122 ? 147.236 127.386 123.724 1.00 300.11 ?  122  VAL B O   1 
ATOM   3642 C CB  . VAL B 1 122 ? 147.672 124.152 122.910 1.00 300.11 ?  122  VAL B CB  1 
ATOM   3643 C CG1 . VAL B 1 122 ? 148.809 124.565 123.833 1.00 300.11 ?  122  VAL B CG1 1 
ATOM   3644 C CG2 . VAL B 1 122 ? 146.965 122.926 123.460 1.00 300.11 ?  122  VAL B CG2 1 
ATOM   3645 N N   . LEU B 1 123 ? 148.061 127.004 121.679 1.00 294.58 ?  123  LEU B N   1 
ATOM   3646 C CA  . LEU B 1 123 ? 148.769 128.271 121.638 1.00 294.58 ?  123  LEU B CA  1 
ATOM   3647 C C   . LEU B 1 123 ? 147.796 129.423 121.755 1.00 294.58 ?  123  LEU B C   1 
ATOM   3648 O O   . LEU B 1 123 ? 148.049 130.361 122.492 1.00 294.58 ?  123  LEU B O   1 
ATOM   3649 C CB  . LEU B 1 123 ? 149.574 128.391 120.348 1.00 294.58 ?  123  LEU B CB  1 
ATOM   3650 C CG  . LEU B 1 123 ? 151.096 128.322 120.473 1.00 294.58 ?  123  LEU B CG  1 
ATOM   3651 C CD1 . LEU B 1 123 ? 151.612 129.454 121.346 1.00 294.58 ?  123  LEU B CD1 1 
ATOM   3652 C CD2 . LEU B 1 123 ? 151.536 126.974 121.020 1.00 294.58 ?  123  LEU B CD2 1 
ATOM   3653 N N   . LEU B 1 124 ? 146.681 129.355 121.036 1.00 286.31 ?  124  LEU B N   1 
ATOM   3654 C CA  . LEU B 1 124 ? 145.667 130.399 121.109 1.00 286.31 ?  124  LEU B CA  1 
ATOM   3655 C C   . LEU B 1 124 ? 145.229 130.614 122.540 1.00 286.31 ?  124  LEU B C   1 
ATOM   3656 O O   . LEU B 1 124 ? 145.296 131.725 123.047 1.00 286.31 ?  124  LEU B O   1 
ATOM   3657 C CB  . LEU B 1 124 ? 144.456 130.018 120.266 1.00 286.31 ?  124  LEU B CB  1 
ATOM   3658 C CG  . LEU B 1 124 ? 144.183 130.863 119.028 1.00 286.31 ?  124  LEU B CG  1 
ATOM   3659 C CD1 . LEU B 1 124 ? 142.688 131.031 118.833 1.00 286.31 ?  124  LEU B CD1 1 
ATOM   3660 C CD2 . LEU B 1 124 ? 144.860 132.212 119.163 1.00 286.31 ?  124  LEU B CD2 1 
ATOM   3661 N N   . GLY B 1 125 ? 144.781 129.552 123.195 1.00 272.55 ?  125  GLY B N   1 
ATOM   3662 C CA  . GLY B 1 125 ? 144.340 129.657 124.570 1.00 272.55 ?  125  GLY B CA  1 
ATOM   3663 C C   . GLY B 1 125 ? 145.401 130.234 125.473 1.00 272.55 ?  125  GLY B C   1 
ATOM   3664 O O   . GLY B 1 125 ? 145.133 131.162 126.224 1.00 272.55 ?  125  GLY B O   1 
ATOM   3665 N N   . LEU B 1 126 ? 146.610 129.698 125.401 1.00 275.46 ?  126  LEU B N   1 
ATOM   3666 C CA  . LEU B 1 126 ? 147.696 130.185 126.233 1.00 275.46 ?  126  LEU B CA  1 
ATOM   3667 C C   . LEU B 1 126 ? 147.961 131.653 125.972 1.00 275.46 ?  126  LEU B C   1 
ATOM   3668 O O   . LEU B 1 126 ? 147.964 132.454 126.899 1.00 275.46 ?  126  LEU B O   1 
ATOM   3669 C CB  . LEU B 1 126 ? 148.962 129.371 125.985 1.00 275.46 ?  126  LEU B CB  1 
ATOM   3670 C CG  . LEU B 1 126 ? 150.278 129.900 126.551 1.00 275.46 ?  126  LEU B CG  1 
ATOM   3671 C CD1 . LEU B 1 126 ? 150.585 129.246 127.888 1.00 275.46 ?  126  LEU B CD1 1 
ATOM   3672 C CD2 . LEU B 1 126 ? 151.407 129.665 125.561 1.00 275.46 ?  126  LEU B CD2 1 
ATOM   3673 N N   . LEU B 1 127 ? 148.168 132.017 124.713 1.00 310.34 ?  127  LEU B N   1 
ATOM   3674 C CA  . LEU B 1 127 ? 148.481 133.398 124.379 1.00 310.34 ?  127  LEU B CA  1 
ATOM   3675 C C   . LEU B 1 127 ? 147.389 134.338 124.836 1.00 310.34 ?  127  LEU B C   1 
ATOM   3676 O O   . LEU B 1 127 ? 147.670 135.371 125.424 1.00 310.34 ?  127  LEU B O   1 
ATOM   3677 C CB  . LEU B 1 127 ? 148.704 133.559 122.878 1.00 310.34 ?  127  LEU B CB  1 
ATOM   3678 C CG  . LEU B 1 127 ? 150.123 133.304 122.366 1.00 310.34 ?  127  LEU B CG  1 
ATOM   3679 C CD1 . LEU B 1 127 ? 150.497 134.333 121.312 1.00 310.34 ?  127  LEU B CD1 1 
ATOM   3680 C CD2 . LEU B 1 127 ? 151.129 133.314 123.506 1.00 310.34 ?  127  LEU B CD2 1 
ATOM   3681 N N   . MET B 1 128 ? 146.142 133.986 124.564 1.00 291.41 ?  128  MET B N   1 
ATOM   3682 C CA  . MET B 1 128 ? 145.030 134.839 124.949 1.00 291.41 ?  128  MET B CA  1 
ATOM   3683 C C   . MET B 1 128 ? 144.941 135.005 126.457 1.00 291.41 ?  128  MET B C   1 
ATOM   3684 O O   . MET B 1 128 ? 144.756 136.112 126.933 1.00 291.41 ?  128  MET B O   1 
ATOM   3685 C CB  . MET B 1 128 ? 143.717 134.311 124.385 1.00 291.41 ?  128  MET B CB  1 
ATOM   3686 C CG  . MET B 1 128 ? 143.157 135.173 123.270 1.00 291.41 ?  128  MET B CG  1 
ATOM   3687 S SD  . MET B 1 128 ? 143.995 136.763 123.150 1.00 291.41 ?  128  MET B SD  1 
ATOM   3688 C CE  . MET B 1 128 ? 142.842 137.811 124.032 1.00 291.41 ?  128  MET B CE  1 
ATOM   3689 N N   . ALA B 1 129 ? 145.070 133.918 127.208 1.00 293.14 ?  129  ALA B N   1 
ATOM   3690 C CA  . ALA B 1 129 ? 145.042 134.003 128.652 1.00 293.14 ?  129  ALA B CA  1 
ATOM   3691 C C   . ALA B 1 129 ? 146.116 134.951 129.136 1.00 293.14 ?  129  ALA B C   1 
ATOM   3692 O O   . ALA B 1 129 ? 145.863 135.784 129.991 1.00 293.14 ?  129  ALA B O   1 
ATOM   3693 C CB  . ALA B 1 129 ? 145.233 132.634 129.260 1.00 293.14 ?  129  ALA B CB  1 
ATOM   3694 N N   . LEU B 1 130 ? 147.314 134.836 128.580 1.00 300.42 ?  130  LEU B N   1 
ATOM   3695 C CA  . LEU B 1 130 ? 148.413 135.701 128.981 1.00 300.42 ?  130  LEU B CA  1 
ATOM   3696 C C   . LEU B 1 130 ? 148.146 137.159 128.645 1.00 300.42 ?  130  LEU B C   1 
ATOM   3697 O O   . LEU B 1 130 ? 148.312 138.024 129.495 1.00 300.42 ?  130  LEU B O   1 
ATOM   3698 C CB  . LEU B 1 130 ? 149.714 135.238 128.331 1.00 300.42 ?  130  LEU B CB  1 
ATOM   3699 C CG  . LEU B 1 130 ? 150.265 133.902 128.823 1.00 300.42 ?  130  LEU B CG  1 
ATOM   3700 C CD1 . LEU B 1 130 ? 151.461 133.481 127.987 1.00 300.42 ?  130  LEU B CD1 1 
ATOM   3701 C CD2 . LEU B 1 130 ? 150.630 133.980 130.297 1.00 300.42 ?  130  LEU B CD2 1 
ATOM   3702 N N   . VAL B 1 131 ? 147.732 137.437 127.415 1.00 275.05 ?  131  VAL B N   1 
ATOM   3703 C CA  . VAL B 1 131 ? 147.430 138.805 127.007 1.00 275.05 ?  131  VAL B CA  1 
ATOM   3704 C C   . VAL B 1 131 ? 146.303 139.375 127.849 1.00 275.05 ?  131  VAL B C   1 
ATOM   3705 O O   . VAL B 1 131 ? 146.416 140.475 128.373 1.00 275.05 ?  131  VAL B O   1 
ATOM   3706 C CB  . VAL B 1 131 ? 147.066 138.875 125.511 1.00 275.05 ?  131  VAL B CB  1 
ATOM   3707 C CG1 . VAL B 1 131 ? 146.519 140.243 125.141 1.00 275.05 ?  131  VAL B CG1 1 
ATOM   3708 C CG2 . VAL B 1 131 ? 148.280 138.548 124.659 1.00 275.05 ?  131  VAL B CG2 1 
ATOM   3709 N N   . SER B 1 132 ? 145.224 138.621 128.006 1.00 258.77 ?  132  SER B N   1 
ATOM   3710 C CA  . SER B 1 132 ? 144.094 139.076 128.803 1.00 258.77 ?  132  SER B CA  1 
ATOM   3711 C C   . SER B 1 132 ? 144.492 139.336 130.240 1.00 258.77 ?  132  SER B C   1 
ATOM   3712 O O   . SER B 1 132 ? 144.088 140.334 130.824 1.00 258.77 ?  132  SER B O   1 
ATOM   3713 C CB  . SER B 1 132 ? 142.971 138.047 128.765 1.00 258.77 ?  132  SER B CB  1 
ATOM   3714 O OG  . SER B 1 132 ? 142.015 138.301 129.777 1.00 258.77 ?  132  SER B OG  1 
ATOM   3715 N N   . TRP B 1 133 ? 145.280 138.440 130.818 1.00 271.73 ?  133  TRP B N   1 
ATOM   3716 C CA  . TRP B 1 133 ? 145.725 138.619 132.186 1.00 271.73 ?  133  TRP B CA  1 
ATOM   3717 C C   . TRP B 1 133 ? 146.549 139.880 132.293 1.00 271.73 ?  133  TRP B C   1 
ATOM   3718 O O   . TRP B 1 133 ? 146.321 140.685 133.178 1.00 271.73 ?  133  TRP B O   1 
ATOM   3719 C CB  . TRP B 1 133 ? 146.542 137.423 132.665 1.00 271.73 ?  133  TRP B CB  1 
ATOM   3720 C CG  . TRP B 1 133 ? 146.875 137.480 134.117 1.00 271.73 ?  133  TRP B CG  1 
ATOM   3721 C CD1 . TRP B 1 133 ? 146.098 137.055 135.152 1.00 271.73 ?  133  TRP B CD1 1 
ATOM   3722 C CD2 . TRP B 1 133 ? 148.074 137.999 134.700 1.00 271.73 ?  133  TRP B CD2 1 
ATOM   3723 N NE1 . TRP B 1 133 ? 146.740 137.277 136.345 1.00 271.73 ?  133  TRP B NE1 1 
ATOM   3724 C CE2 . TRP B 1 133 ? 147.954 137.857 136.094 1.00 271.73 ?  133  TRP B CE2 1 
ATOM   3725 C CE3 . TRP B 1 133 ? 149.236 138.573 134.178 1.00 271.73 ?  133  TRP B CE3 1 
ATOM   3726 C CZ2 . TRP B 1 133 ? 148.951 138.265 136.971 1.00 271.73 ?  133  TRP B CZ2 1 
ATOM   3727 C CZ3 . TRP B 1 133 ? 150.223 138.978 135.049 1.00 271.73 ?  133  TRP B CZ3 1 
ATOM   3728 C CH2 . TRP B 1 133 ? 150.076 138.822 136.431 1.00 271.73 ?  133  TRP B CH2 1 
ATOM   3729 N N   . SER B 1 134 ? 147.509 140.054 131.395 1.00 256.83 ?  134  SER B N   1 
ATOM   3730 C CA  . SER B 1 134 ? 148.356 141.235 131.419 1.00 256.83 ?  134  SER B CA  1 
ATOM   3731 C C   . SER B 1 134 ? 147.519 142.488 131.310 1.00 256.83 ?  134  SER B C   1 
ATOM   3732 O O   . SER B 1 134 ? 147.680 143.411 132.099 1.00 256.83 ?  134  SER B O   1 
ATOM   3733 C CB  . SER B 1 134 ? 149.364 141.182 130.280 1.00 256.83 ?  134  SER B CB  1 
ATOM   3734 O OG  . SER B 1 134 ? 150.149 140.007 130.358 1.00 256.83 ?  134  SER B OG  1 
ATOM   3735 N N   . MET B 1 135 ? 146.619 142.524 130.338 1.00 225.39 ?  135  MET B N   1 
ATOM   3736 C CA  . MET B 1 135 ? 145.734 143.666 130.169 1.00 225.39 ?  135  MET B CA  1 
ATOM   3737 C C   . MET B 1 135 ? 144.973 143.935 131.452 1.00 225.39 ?  135  MET B C   1 
ATOM   3738 O O   . MET B 1 135 ? 145.014 145.041 131.978 1.00 225.39 ?  135  MET B O   1 
ATOM   3739 C CB  . MET B 1 135 ? 144.764 143.380 129.027 1.00 225.39 ?  135  MET B CB  1 
ATOM   3740 C CG  . MET B 1 135 ? 143.753 144.470 128.732 1.00 225.39 ?  135  MET B CG  1 
ATOM   3741 S SD  . MET B 1 135 ? 143.530 144.617 126.953 1.00 225.39 ?  135  MET B SD  1 
ATOM   3742 C CE  . MET B 1 135 ? 144.442 143.181 126.399 1.00 225.39 ?  135  MET B CE  1 
ATOM   3743 N N   . GLY B 1 136 ? 144.293 142.924 131.974 1.00 217.14 ?  136  GLY B N   1 
ATOM   3744 C CA  . GLY B 1 136 ? 143.533 143.083 133.198 1.00 217.14 ?  136  GLY B CA  1 
ATOM   3745 C C   . GLY B 1 136 ? 144.372 143.482 134.386 1.00 217.14 ?  136  GLY B C   1 
ATOM   3746 O O   . GLY B 1 136 ? 143.931 144.271 135.208 1.00 217.14 ?  136  GLY B O   1 
ATOM   3747 N N   . TYR B 1 137 ? 145.579 142.945 134.485 1.00 223.63 ?  137  TYR B N   1 
ATOM   3748 C CA  . TYR B 1 137 ? 146.470 143.283 135.582 1.00 223.63 ?  137  TYR B CA  1 
ATOM   3749 C C   . TYR B 1 137 ? 146.793 144.762 135.561 1.00 223.63 ?  137  TYR B C   1 
ATOM   3750 O O   . TYR B 1 137 ? 146.634 145.443 136.567 1.00 223.63 ?  137  TYR B O   1 
ATOM   3751 C CB  . TYR B 1 137 ? 147.759 142.468 135.488 1.00 223.63 ?  137  TYR B CB  1 
ATOM   3752 C CG  . TYR B 1 137 ? 148.760 142.749 136.580 1.00 223.63 ?  137  TYR B CG  1 
ATOM   3753 C CD1 . TYR B 1 137 ? 148.613 142.192 137.838 1.00 223.63 ?  137  TYR B CD1 1 
ATOM   3754 C CD2 . TYR B 1 137 ? 149.860 143.564 136.349 1.00 223.63 ?  137  TYR B CD2 1 
ATOM   3755 C CE1 . TYR B 1 137 ? 149.527 142.442 138.841 1.00 223.63 ?  137  TYR B CE1 1 
ATOM   3756 C CE2 . TYR B 1 137 ? 150.777 143.822 137.347 1.00 223.63 ?  137  TYR B CE2 1 
ATOM   3757 C CZ  . TYR B 1 137 ? 150.605 143.257 138.591 1.00 223.63 ?  137  TYR B CZ  1 
ATOM   3758 O OH  . TYR B 1 137 ? 151.515 143.508 139.590 1.00 223.63 ?  137  TYR B OH  1 
ATOM   3759 N N   . VAL B 1 138 ? 147.244 145.267 134.419 1.00 233.63 ?  138  VAL B N   1 
ATOM   3760 C CA  . VAL B 1 138 ? 147.619 146.671 134.326 1.00 233.63 ?  138  VAL B CA  1 
ATOM   3761 C C   . VAL B 1 138 ? 146.402 147.562 134.515 1.00 233.63 ?  138  VAL B C   1 
ATOM   3762 O O   . VAL B 1 138 ? 146.490 148.607 135.151 1.00 233.63 ?  138  VAL B O   1 
ATOM   3763 C CB  . VAL B 1 138 ? 148.331 146.983 132.998 1.00 233.63 ?  138  VAL B CB  1 
ATOM   3764 C CG1 . VAL B 1 138 ? 148.815 148.424 132.968 1.00 233.63 ?  138  VAL B CG1 1 
ATOM   3765 C CG2 . VAL B 1 138 ? 149.506 146.040 132.799 1.00 233.63 ?  138  VAL B CG2 1 
ATOM   3766 N N   . SER B 1 139 ? 145.255 147.139 133.997 1.00 209.26 ?  139  SER B N   1 
ATOM   3767 C CA  . SER B 1 139 ? 144.032 147.915 134.155 1.00 209.26 ?  139  SER B CA  1 
ATOM   3768 C C   . SER B 1 139 ? 143.607 147.979 135.612 1.00 209.26 ?  139  SER B C   1 
ATOM   3769 O O   . SER B 1 139 ? 143.138 149.011 136.076 1.00 209.26 ?  139  SER B O   1 
ATOM   3770 C CB  . SER B 1 139 ? 142.916 147.316 133.306 1.00 209.26 ?  139  SER B CB  1 
ATOM   3771 O OG  . SER B 1 139 ? 141.889 146.777 134.117 1.00 209.26 ?  139  SER B OG  1 
ATOM   3772 N N   . ALA B 1 140 ? 143.780 146.884 136.341 1.00 212.88 ?  140  ALA B N   1 
ATOM   3773 C CA  . ALA B 1 140 ? 143.428 146.858 137.752 1.00 212.88 ?  140  ALA B CA  1 
ATOM   3774 C C   . ALA B 1 140 ? 144.384 147.707 138.555 1.00 212.88 ?  140  ALA B C   1 
ATOM   3775 O O   . ALA B 1 140 ? 143.984 148.348 139.518 1.00 212.88 ?  140  ALA B O   1 
ATOM   3776 C CB  . ALA B 1 140 ? 143.436 145.436 138.272 1.00 212.88 ?  140  ALA B CB  1 
ATOM   3777 N N   . LYS B 1 141 ? 145.650 147.719 138.161 1.00 223.66 ?  141  LYS B N   1 
ATOM   3778 C CA  . LYS B 1 141 ? 146.638 148.525 138.860 1.00 223.66 ?  141  LYS B CA  1 
ATOM   3779 C C   . LYS B 1 141 ? 146.365 149.989 138.599 1.00 223.66 ?  141  LYS B C   1 
ATOM   3780 O O   . LYS B 1 141 ? 146.598 150.831 139.460 1.00 223.66 ?  141  LYS B O   1 
ATOM   3781 C CB  . LYS B 1 141 ? 148.053 148.159 138.416 1.00 223.66 ?  141  LYS B CB  1 
ATOM   3782 C CG  . LYS B 1 141 ? 148.548 146.799 138.886 1.00 223.66 ?  141  LYS B CG  1 
ATOM   3783 C CD  . LYS B 1 141 ? 147.986 146.414 140.244 1.00 223.66 ?  141  LYS B CD  1 
ATOM   3784 C CE  . LYS B 1 141 ? 147.283 145.066 140.187 1.00 223.66 ?  141  LYS B CE  1 
ATOM   3785 N NZ  . LYS B 1 141 ? 146.972 144.534 141.541 1.00 223.66 1  141  LYS B NZ  1 
ATOM   3786 N N   . SER B 1 142 ? 145.859 150.299 137.413 1.00 217.81 ?  142  SER B N   1 
ATOM   3787 C CA  . SER B 1 142 ? 145.533 151.674 137.079 1.00 217.81 ?  142  SER B CA  1 
ATOM   3788 C C   . SER B 1 142 ? 144.321 152.116 137.863 1.00 217.81 ?  142  SER B C   1 
ATOM   3789 O O   . SER B 1 142 ? 144.258 153.247 138.327 1.00 217.81 ?  142  SER B O   1 
ATOM   3790 C CB  . SER B 1 142 ? 145.265 151.807 135.587 1.00 217.81 ?  142  SER B CB  1 
ATOM   3791 O OG  . SER B 1 142 ? 144.457 152.931 135.326 1.00 217.81 ?  142  SER B OG  1 
ATOM   3792 N N   . LEU B 1 143 ? 143.355 151.222 138.026 1.00 215.31 ?  143  LEU B N   1 
ATOM   3793 C CA  . LEU B 1 143 ? 142.167 151.542 138.802 1.00 215.31 ?  143  LEU B CA  1 
ATOM   3794 C C   . LEU B 1 143 ? 142.530 151.743 140.261 1.00 215.31 ?  143  LEU B C   1 
ATOM   3795 O O   . LEU B 1 143 ? 141.925 152.559 140.947 1.00 215.31 ?  143  LEU B O   1 
ATOM   3796 C CB  . LEU B 1 143 ? 141.135 150.428 138.667 1.00 215.31 ?  143  LEU B CB  1 
ATOM   3797 C CG  . LEU B 1 143 ? 139.789 150.808 138.060 1.00 215.31 ?  143  LEU B CG  1 
ATOM   3798 C CD1 . LEU B 1 143 ? 139.852 152.194 137.443 1.00 215.31 ?  143  LEU B CD1 1 
ATOM   3799 C CD2 . LEU B 1 143 ? 139.360 149.773 137.035 1.00 215.31 ?  143  LEU B CD2 1 
ATOM   3800 N N   . GLN B 1 144 ? 143.524 151.007 140.741 1.00 242.10 ?  144  GLN B N   1 
ATOM   3801 C CA  . GLN B 1 144 ? 143.963 151.158 142.118 1.00 242.10 ?  144  GLN B CA  1 
ATOM   3802 C C   . GLN B 1 144 ? 144.664 152.485 142.312 1.00 242.10 ?  144  GLN B C   1 
ATOM   3803 O O   . GLN B 1 144 ? 144.496 153.123 143.343 1.00 242.10 ?  144  GLN B O   1 
ATOM   3804 C CB  . GLN B 1 144 ? 144.893 150.017 142.514 1.00 242.10 ?  144  GLN B CB  1 
ATOM   3805 C CG  . GLN B 1 144 ? 144.171 148.749 142.930 1.00 242.10 ?  144  GLN B CG  1 
ATOM   3806 C CD  . GLN B 1 144 ? 145.030 147.515 142.757 1.00 242.10 ?  144  GLN B CD  1 
ATOM   3807 O OE1 . GLN B 1 144 ? 144.589 146.508 142.206 1.00 242.10 ?  144  GLN B OE1 1 
ATOM   3808 N NE2 . GLN B 1 144 ? 146.268 147.588 143.229 1.00 242.10 ?  144  GLN B NE2 1 
ATOM   3809 N N   . ALA B 1 145 ? 145.448 152.909 141.327 1.00 229.27 ?  145  ALA B N   1 
ATOM   3810 C CA  . ALA B 1 145 ? 146.118 154.200 141.409 1.00 229.27 ?  145  ALA B CA  1 
ATOM   3811 C C   . ALA B 1 145 ? 145.086 155.298 141.363 1.00 229.27 ?  145  ALA B C   1 
ATOM   3812 O O   . ALA B 1 145 ? 145.226 156.303 142.043 1.00 229.27 ?  145  ALA B O   1 
ATOM   3813 C CB  . ALA B 1 145 ? 147.102 154.359 140.273 1.00 229.27 ?  145  ALA B CB  1 
ATOM   3814 N N   . TYR B 1 146 ? 144.045 155.114 140.561 1.00 220.90 ?  146  TYR B N   1 
ATOM   3815 C CA  . TYR B 1 146 ? 142.963 156.085 140.480 1.00 220.90 ?  146  TYR B CA  1 
ATOM   3816 C C   . TYR B 1 146 ? 142.387 156.273 141.861 1.00 220.90 ?  146  TYR B C   1 
ATOM   3817 O O   . TYR B 1 146 ? 142.332 157.389 142.369 1.00 220.90 ?  146  TYR B O   1 
ATOM   3818 C CB  . TYR B 1 146 ? 141.905 155.522 139.539 1.00 220.90 ?  146  TYR B CB  1 
ATOM   3819 C CG  . TYR B 1 146 ? 140.750 156.419 139.177 1.00 220.90 ?  146  TYR B CG  1 
ATOM   3820 C CD1 . TYR B 1 146 ? 140.824 157.797 139.316 1.00 220.90 ?  146  TYR B CD1 1 
ATOM   3821 C CD2 . TYR B 1 146 ? 139.582 155.874 138.673 1.00 220.90 ?  146  TYR B CD2 1 
ATOM   3822 C CE1 . TYR B 1 146 ? 139.757 158.601 138.972 1.00 220.90 ?  146  TYR B CE1 1 
ATOM   3823 C CE2 . TYR B 1 146 ? 138.515 156.668 138.328 1.00 220.90 ?  146  TYR B CE2 1 
ATOM   3824 C CZ  . TYR B 1 146 ? 138.607 158.028 138.479 1.00 220.90 ?  146  TYR B CZ  1 
ATOM   3825 O OH  . TYR B 1 146 ? 137.533 158.803 138.127 1.00 220.90 ?  146  TYR B OH  1 
ATOM   3826 N N   . LYS B 1 147 ? 141.969 155.179 142.482 1.00 198.72 ?  147  LYS B N   1 
ATOM   3827 C CA  . LYS B 1 147 ? 141.384 155.253 143.812 1.00 198.72 ?  147  LYS B CA  1 
ATOM   3828 C C   . LYS B 1 147 ? 142.344 155.842 144.832 1.00 198.72 ?  147  LYS B C   1 
ATOM   3829 O O   . LYS B 1 147 ? 141.954 156.684 145.636 1.00 198.72 ?  147  LYS B O   1 
ATOM   3830 C CB  . LYS B 1 147 ? 140.927 153.869 144.264 1.00 198.72 ?  147  LYS B CB  1 
ATOM   3831 C CG  . LYS B 1 147 ? 139.507 153.525 143.855 1.00 198.72 ?  147  LYS B CG  1 
ATOM   3832 C CD  . LYS B 1 147 ? 139.423 152.120 143.286 1.00 198.72 ?  147  LYS B CD  1 
ATOM   3833 C CE  . LYS B 1 147 ? 138.403 152.048 142.164 1.00 198.72 ?  147  LYS B CE  1 
ATOM   3834 N NZ  . LYS B 1 147 ? 137.168 152.806 142.508 1.00 198.72 1  147  LYS B NZ  1 
ATOM   3835 N N   . TRP B 1 148 ? 143.598 155.409 144.801 1.00 237.89 ?  148  TRP B N   1 
ATOM   3836 C CA  . TRP B 1 148 ? 144.586 155.904 145.751 1.00 237.89 ?  148  TRP B CA  1 
ATOM   3837 C C   . TRP B 1 148 ? 144.827 157.399 145.600 1.00 237.89 ?  148  TRP B C   1 
ATOM   3838 O O   . TRP B 1 148 ? 144.863 158.123 146.588 1.00 237.89 ?  148  TRP B O   1 
ATOM   3839 C CB  . TRP B 1 148 ? 145.900 155.138 145.607 1.00 237.89 ?  148  TRP B CB  1 
ATOM   3840 C CG  . TRP B 1 148 ? 147.050 155.776 146.311 1.00 237.89 ?  148  TRP B CG  1 
ATOM   3841 C CD1 . TRP B 1 148 ? 147.286 155.786 147.653 1.00 237.89 ?  148  TRP B CD1 1 
ATOM   3842 C CD2 . TRP B 1 148 ? 148.126 156.504 145.708 1.00 237.89 ?  148  TRP B CD2 1 
ATOM   3843 N NE1 . TRP B 1 148 ? 148.442 156.475 147.925 1.00 237.89 ?  148  TRP B NE1 1 
ATOM   3844 C CE2 . TRP B 1 148 ? 148.976 156.926 146.747 1.00 237.89 ?  148  TRP B CE2 1 
ATOM   3845 C CE3 . TRP B 1 148 ? 148.451 156.840 144.392 1.00 237.89 ?  148  TRP B CE3 1 
ATOM   3846 C CZ2 . TRP B 1 148 ? 150.131 157.665 146.510 1.00 237.89 ?  148  TRP B CZ2 1 
ATOM   3847 C CZ3 . TRP B 1 148 ? 149.595 157.574 144.159 1.00 237.89 ?  148  TRP B CZ3 1 
ATOM   3848 C CH2 . TRP B 1 148 ? 150.422 157.977 145.212 1.00 237.89 ?  148  TRP B CH2 1 
ATOM   3849 N N   . SER B 1 149 ? 144.987 157.866 144.368 1.00 206.54 ?  149  SER B N   1 
ATOM   3850 C CA  . SER B 1 149 ? 145.247 159.279 144.135 1.00 206.54 ?  149  SER B CA  1 
ATOM   3851 C C   . SER B 1 149 ? 144.067 160.115 144.575 1.00 206.54 ?  149  SER B C   1 
ATOM   3852 O O   . SER B 1 149 ? 144.235 161.189 145.152 1.00 206.54 ?  149  SER B O   1 
ATOM   3853 C CB  . SER B 1 149 ? 145.546 159.535 142.664 1.00 206.54 ?  149  SER B CB  1 
ATOM   3854 O OG  . SER B 1 149 ? 146.671 158.793 142.235 1.00 206.54 ?  149  SER B OG  1 
ATOM   3855 N N   . TYR B 1 150 ? 142.863 159.625 144.312 1.00 168.90 ?  150  TYR B N   1 
ATOM   3856 C CA  . TYR B 1 150 ? 141.667 160.342 144.713 1.00 168.90 ?  150  TYR B CA  1 
ATOM   3857 C C   . TYR B 1 150 ? 141.646 160.473 146.222 1.00 168.90 ?  150  TYR B C   1 
ATOM   3858 O O   . TYR B 1 150 ? 141.365 161.544 146.754 1.00 168.90 ?  150  TYR B O   1 
ATOM   3859 C CB  . TYR B 1 150 ? 140.432 159.598 144.201 1.00 168.90 ?  150  TYR B CB  1 
ATOM   3860 C CG  . TYR B 1 150 ? 139.118 160.065 144.773 1.00 168.90 ?  150  TYR B CG  1 
ATOM   3861 C CD1 . TYR B 1 150 ? 138.521 161.236 144.330 1.00 168.90 ?  150  TYR B CD1 1 
ATOM   3862 C CD2 . TYR B 1 150 ? 138.467 159.323 145.747 1.00 168.90 ?  150  TYR B CD2 1 
ATOM   3863 C CE1 . TYR B 1 150 ? 137.313 161.658 144.848 1.00 168.90 ?  150  TYR B CE1 1 
ATOM   3864 C CE2 . TYR B 1 150 ? 137.265 159.740 146.274 1.00 168.90 ?  150  TYR B CE2 1 
ATOM   3865 C CZ  . TYR B 1 150 ? 136.694 160.905 145.821 1.00 168.90 ?  150  TYR B CZ  1 
ATOM   3866 O OH  . TYR B 1 150 ? 135.499 161.309 146.355 1.00 168.90 ?  150  TYR B OH  1 
ATOM   3867 N N   . ALA B 1 151 ? 141.970 159.391 146.918 1.00 187.55 ?  151  ALA B N   1 
ATOM   3868 C CA  . ALA B 1 151 ? 141.930 159.405 148.373 1.00 187.55 ?  151  ALA B CA  1 
ATOM   3869 C C   . ALA B 1 151 ? 143.082 160.175 148.994 1.00 187.55 ?  151  ALA B C   1 
ATOM   3870 O O   . ALA B 1 151 ? 143.023 160.542 150.164 1.00 187.55 ?  151  ALA B O   1 
ATOM   3871 C CB  . ALA B 1 151 ? 141.901 157.985 148.906 1.00 187.55 ?  151  ALA B CB  1 
ATOM   3872 N N   . GLN B 1 152 ? 144.135 160.416 148.223 1.00 228.04 ?  152  GLN B N   1 
ATOM   3873 C CA  . GLN B 1 152 ? 145.275 161.161 148.736 1.00 228.04 ?  152  GLN B CA  1 
ATOM   3874 C C   . GLN B 1 152 ? 144.949 162.647 148.778 1.00 228.04 ?  152  GLN B C   1 
ATOM   3875 O O   . GLN B 1 152 ? 145.530 163.391 149.567 1.00 228.04 ?  152  GLN B O   1 
ATOM   3876 C CB  . GLN B 1 152 ? 146.540 160.861 147.922 1.00 228.04 ?  152  GLN B CB  1 
ATOM   3877 C CG  . GLN B 1 152 ? 147.056 162.006 147.067 1.00 228.04 ?  152  GLN B CG  1 
ATOM   3878 C CD  . GLN B 1 152 ? 147.636 161.533 145.751 1.00 228.04 ?  152  GLN B CD  1 
ATOM   3879 O OE1 . GLN B 1 152 ? 148.249 160.471 145.679 1.00 228.04 ?  152  GLN B OE1 1 
ATOM   3880 N NE2 . GLN B 1 152 ? 147.442 162.320 144.700 1.00 228.04 ?  152  GLN B NE2 1 
ATOM   3881 N N   . MET B 1 153 ? 143.998 163.082 147.957 1.00 256.85 ?  153  MET B N   1 
ATOM   3882 C CA  . MET B 1 153 ? 143.581 164.481 147.980 1.00 256.85 ?  153  MET B CA  1 
ATOM   3883 C C   . MET B 1 153 ? 142.338 164.632 148.831 1.00 256.85 ?  153  MET B C   1 
ATOM   3884 O O   . MET B 1 153 ? 141.641 165.635 148.714 1.00 256.85 ?  153  MET B O   1 
ATOM   3885 C CB  . MET B 1 153 ? 143.282 164.970 146.565 1.00 256.85 ?  153  MET B CB  1 
ATOM   3886 C CG  . MET B 1 153 ? 144.293 164.533 145.523 1.00 256.85 ?  153  MET B CG  1 
ATOM   3887 S SD  . MET B 1 153 ? 145.866 165.393 145.688 1.00 256.85 ?  153  MET B SD  1 
ATOM   3888 C CE  . MET B 1 153 ? 146.135 165.931 144.002 1.00 256.85 ?  153  MET B CE  1 
ATOM   3889 N N   . GLN B 1 154 ? 142.067 163.663 149.698 1.00 267.26 ?  154  GLN B N   1 
ATOM   3890 C CA  . GLN B 1 154 ? 140.841 163.672 150.510 1.00 267.26 ?  154  GLN B CA  1 
ATOM   3891 C C   . GLN B 1 154 ? 140.256 165.009 150.986 1.00 267.26 ?  154  GLN B C   1 
ATOM   3892 O O   . GLN B 1 154 ? 139.128 165.341 150.624 1.00 267.26 ?  154  GLN B O   1 
ATOM   3893 C CB  . GLN B 1 154 ? 140.950 162.681 151.677 1.00 267.26 ?  154  GLN B CB  1 
ATOM   3894 C CG  . GLN B 1 154 ? 139.612 162.150 152.164 1.00 267.26 ?  154  GLN B CG  1 
ATOM   3895 C CD  . GLN B 1 154 ? 138.922 161.277 151.135 1.00 267.26 ?  154  GLN B CD  1 
ATOM   3896 O OE1 . GLN B 1 154 ? 137.887 161.647 150.582 1.00 267.26 ?  154  GLN B OE1 1 
ATOM   3897 N NE2 . GLN B 1 154 ? 139.492 160.107 150.875 1.00 267.26 ?  154  GLN B NE2 1 
ATOM   3898 N N   . PRO B 1 155 ? 140.999 165.780 151.801 1.00 242.74 ?  155  PRO B N   1 
ATOM   3899 C CA  . PRO B 1 155 ? 140.351 167.006 152.287 1.00 242.74 ?  155  PRO B CA  1 
ATOM   3900 C C   . PRO B 1 155 ? 139.970 167.978 151.176 1.00 242.74 ?  155  PRO B C   1 
ATOM   3901 O O   . PRO B 1 155 ? 138.831 168.438 151.148 1.00 242.74 ?  155  PRO B O   1 
ATOM   3902 C CB  . PRO B 1 155 ? 141.418 167.636 153.192 1.00 242.74 ?  155  PRO B CB  1 
ATOM   3903 C CG  . PRO B 1 155 ? 142.379 166.537 153.499 1.00 242.74 ?  155  PRO B CG  1 
ATOM   3904 C CD  . PRO B 1 155 ? 142.392 165.684 152.272 1.00 242.74 ?  155  PRO B CD  1 
ATOM   3905 N N   . SER B 1 156 ? 140.898 168.288 150.278 1.00 232.47 ?  156  SER B N   1 
ATOM   3906 C CA  . SER B 1 156 ? 140.627 169.264 149.228 1.00 232.47 ?  156  SER B CA  1 
ATOM   3907 C C   . SER B 1 156 ? 139.638 168.768 148.192 1.00 232.47 ?  156  SER B C   1 
ATOM   3908 O O   . SER B 1 156 ? 139.974 167.927 147.366 1.00 232.47 ?  156  SER B O   1 
ATOM   3909 C CB  . SER B 1 156 ? 141.924 169.668 148.536 1.00 232.47 ?  156  SER B CB  1 
ATOM   3910 O OG  . SER B 1 156 ? 141.685 170.666 147.560 1.00 232.47 ?  156  SER B OG  1 
ATOM   3911 N N   . LEU B 1 157 ? 138.422 169.300 148.221 1.00 209.06 ?  157  LEU B N   1 
ATOM   3912 C CA  . LEU B 1 157 ? 137.413 168.918 147.233 1.00 209.06 ?  157  LEU B CA  1 
ATOM   3913 C C   . LEU B 1 157 ? 137.757 169.288 145.783 1.00 209.06 ?  157  LEU B C   1 
ATOM   3914 O O   . LEU B 1 157 ? 137.543 168.478 144.884 1.00 209.06 ?  157  LEU B O   1 
ATOM   3915 C CB  . LEU B 1 157 ? 136.035 169.465 147.621 1.00 209.06 ?  157  LEU B CB  1 
ATOM   3916 C CG  . LEU B 1 157 ? 134.940 168.426 147.856 1.00 209.06 ?  157  LEU B CG  1 
ATOM   3917 C CD1 . LEU B 1 157 ? 133.950 168.431 146.703 1.00 209.06 ?  157  LEU B CD1 1 
ATOM   3918 C CD2 . LEU B 1 157 ? 135.549 167.046 148.043 1.00 209.06 ?  157  LEU B CD2 1 
ATOM   3919 N N   . PRO B 1 158 ? 138.281 170.508 145.536 1.00 201.91 ?  158  PRO B N   1 
ATOM   3920 C CA  . PRO B 1 158 ? 138.652 170.773 144.141 1.00 201.91 ?  158  PRO B CA  1 
ATOM   3921 C C   . PRO B 1 158 ? 139.736 169.837 143.614 1.00 201.91 ?  158  PRO B C   1 
ATOM   3922 O O   . PRO B 1 158 ? 139.714 169.492 142.436 1.00 201.91 ?  158  PRO B O   1 
ATOM   3923 C CB  . PRO B 1 158 ? 139.169 172.216 144.176 1.00 201.91 ?  158  PRO B CB  1 
ATOM   3924 C CG  . PRO B 1 158 ? 139.376 172.543 145.616 1.00 201.91 ?  158  PRO B CG  1 
ATOM   3925 C CD  . PRO B 1 158 ? 138.352 171.736 146.345 1.00 201.91 ?  158  PRO B CD  1 
ATOM   3926 N N   . LEU B 1 159 ? 140.667 169.427 144.469 1.00 219.69 ?  159  LEU B N   1 
ATOM   3927 C CA  . LEU B 1 159 ? 141.726 168.525 144.047 1.00 219.69 ?  159  LEU B CA  1 
ATOM   3928 C C   . LEU B 1 159 ? 141.188 167.124 143.852 1.00 219.69 ?  159  LEU B C   1 
ATOM   3929 O O   . LEU B 1 159 ? 141.657 166.396 142.982 1.00 219.69 ?  159  LEU B O   1 
ATOM   3930 C CB  . LEU B 1 159 ? 142.866 168.520 145.056 1.00 219.69 ?  159  LEU B CB  1 
ATOM   3931 C CG  . LEU B 1 159 ? 143.890 169.639 144.887 1.00 219.69 ?  159  LEU B CG  1 
ATOM   3932 C CD1 . LEU B 1 159 ? 145.054 169.440 145.844 1.00 219.69 ?  159  LEU B CD1 1 
ATOM   3933 C CD2 . LEU B 1 159 ? 144.374 169.697 143.447 1.00 219.69 ?  159  LEU B CD2 1 
ATOM   3934 N N   . GLN B 1 160 ? 140.204 166.735 144.654 1.00 190.31 ?  160  GLN B N   1 
ATOM   3935 C CA  . GLN B 1 160 ? 139.582 165.433 144.468 1.00 190.31 ?  160  GLN B CA  1 
ATOM   3936 C C   . GLN B 1 160 ? 138.924 165.421 143.107 1.00 190.31 ?  160  GLN B C   1 
ATOM   3937 O O   . GLN B 1 160 ? 138.990 164.425 142.397 1.00 190.31 ?  160  GLN B O   1 
ATOM   3938 C CB  . GLN B 1 160 ? 138.550 165.163 145.555 1.00 190.31 ?  160  GLN B CB  1 
ATOM   3939 C CG  . GLN B 1 160 ? 139.153 164.699 146.866 1.00 190.31 ?  160  GLN B CG  1 
ATOM   3940 C CD  . GLN B 1 160 ? 138.285 163.697 147.594 1.00 190.31 ?  160  GLN B CD  1 
ATOM   3941 O OE1 . GLN B 1 160 ? 137.118 163.959 147.877 1.00 190.31 ?  160  GLN B OE1 1 
ATOM   3942 N NE2 . GLN B 1 160 ? 138.853 162.540 147.904 1.00 190.31 ?  160  GLN B NE2 1 
ATOM   3943 N N   . PHE B 1 161 ? 138.304 166.535 142.731 1.00 210.02 ?  161  PHE B N   1 
ATOM   3944 C CA  . PHE B 1 161 ? 137.686 166.635 141.415 1.00 210.02 ?  161  PHE B CA  1 
ATOM   3945 C C   . PHE B 1 161 ? 138.730 166.474 140.338 1.00 210.02 ?  161  PHE B C   1 
ATOM   3946 O O   . PHE B 1 161 ? 138.534 165.714 139.399 1.00 210.02 ?  161  PHE B O   1 
ATOM   3947 C CB  . PHE B 1 161 ? 136.973 167.976 141.248 1.00 210.02 ?  161  PHE B CB  1 
ATOM   3948 C CG  . PHE B 1 161 ? 136.128 168.061 140.012 1.00 210.02 ?  161  PHE B CG  1 
ATOM   3949 C CD1 . PHE B 1 161 ? 134.957 167.335 139.909 1.00 210.02 ?  161  PHE B CD1 1 
ATOM   3950 C CD2 . PHE B 1 161 ? 136.503 168.870 138.954 1.00 210.02 ?  161  PHE B CD2 1 
ATOM   3951 C CE1 . PHE B 1 161 ? 134.173 167.411 138.776 1.00 210.02 ?  161  PHE B CE1 1 
ATOM   3952 C CE2 . PHE B 1 161 ? 135.726 168.950 137.815 1.00 210.02 ?  161  PHE B CE2 1 
ATOM   3953 C CZ  . PHE B 1 161 ? 134.558 168.220 137.727 1.00 210.02 ?  161  PHE B CZ  1 
ATOM   3954 N N   . LEU B 1 162 ? 139.841 167.187 140.472 1.00 201.58 ?  162  LEU B N   1 
ATOM   3955 C CA  . LEU B 1 162 ? 140.907 167.096 139.486 1.00 201.58 ?  162  LEU B CA  1 
ATOM   3956 C C   . LEU B 1 162 ? 141.293 165.648 139.235 1.00 201.58 ?  162  LEU B C   1 
ATOM   3957 O O   . LEU B 1 162 ? 141.223 165.179 138.111 1.00 201.58 ?  162  LEU B O   1 
ATOM   3958 C CB  . LEU B 1 162 ? 142.124 167.905 139.924 1.00 201.58 ?  162  LEU B CB  1 
ATOM   3959 C CG  . LEU B 1 162 ? 142.370 169.200 139.152 1.00 201.58 ?  162  LEU B CG  1 
ATOM   3960 C CD1 . LEU B 1 162 ? 141.582 169.207 137.853 1.00 201.58 ?  162  LEU B CD1 1 
ATOM   3961 C CD2 . LEU B 1 162 ? 142.013 170.408 140.003 1.00 201.58 ?  162  LEU B CD2 1 
ATOM   3962 N N   . VAL B 1 163 ? 141.679 164.932 140.282 1.00 217.21 ?  163  VAL B N   1 
ATOM   3963 C CA  . VAL B 1 163 ? 142.055 163.534 140.128 1.00 217.21 ?  163  VAL B CA  1 
ATOM   3964 C C   . VAL B 1 163 ? 140.930 162.701 139.525 1.00 217.21 ?  163  VAL B C   1 
ATOM   3965 O O   . VAL B 1 163 ? 141.154 161.936 138.590 1.00 217.21 ?  163  VAL B O   1 
ATOM   3966 C CB  . VAL B 1 163 ? 142.489 162.915 141.462 1.00 217.21 ?  163  VAL B CB  1 
ATOM   3967 C CG1 . VAL B 1 163 ? 142.754 161.430 141.290 1.00 217.21 ?  163  VAL B CG1 1 
ATOM   3968 C CG2 . VAL B 1 163 ? 143.731 163.616 141.979 1.00 217.21 ?  163  VAL B CG2 1 
ATOM   3969 N N   . TRP B 1 164 ? 139.715 162.865 140.035 1.00 191.84 ?  164  TRP B N   1 
ATOM   3970 C CA  . TRP B 1 164 ? 138.590 162.081 139.542 1.00 191.84 ?  164  TRP B CA  1 
ATOM   3971 C C   . TRP B 1 164 ? 138.296 162.281 138.061 1.00 191.84 ?  164  TRP B C   1 
ATOM   3972 O O   . TRP B 1 164 ? 137.787 161.381 137.409 1.00 191.84 ?  164  TRP B O   1 
ATOM   3973 C CB  . TRP B 1 164 ? 137.326 162.339 140.363 1.00 191.84 ?  164  TRP B CB  1 
ATOM   3974 C CG  . TRP B 1 164 ? 136.284 161.288 140.155 1.00 191.84 ?  164  TRP B CG  1 
ATOM   3975 C CD1 . TRP B 1 164 ? 135.196 161.366 139.341 1.00 191.84 ?  164  TRP B CD1 1 
ATOM   3976 C CD2 . TRP B 1 164 ? 136.246 159.987 140.751 1.00 191.84 ?  164  TRP B CD2 1 
ATOM   3977 N NE1 . TRP B 1 164 ? 134.478 160.199 139.396 1.00 191.84 ?  164  TRP B NE1 1 
ATOM   3978 C CE2 . TRP B 1 164 ? 135.102 159.335 140.255 1.00 191.84 ?  164  TRP B CE2 1 
ATOM   3979 C CE3 . TRP B 1 164 ? 137.068 159.310 141.656 1.00 191.84 ?  164  TRP B CE3 1 
ATOM   3980 C CZ2 . TRP B 1 164 ? 134.756 158.044 140.636 1.00 191.84 ?  164  TRP B CZ2 1 
ATOM   3981 C CZ3 . TRP B 1 164 ? 136.724 158.029 142.032 1.00 191.84 ?  164  TRP B CZ3 1 
ATOM   3982 C CH2 . TRP B 1 164 ? 135.578 157.408 141.524 1.00 191.84 ?  164  TRP B CH2 1 
ATOM   3983 N N   . VAL B 1 165 ? 138.591 163.454 137.521 1.00 211.85 ?  165  VAL B N   1 
ATOM   3984 C CA  . VAL B 1 165 ? 138.256 163.697 136.127 1.00 211.85 ?  165  VAL B CA  1 
ATOM   3985 C C   . VAL B 1 165 ? 139.445 163.589 135.186 1.00 211.85 ?  165  VAL B C   1 
ATOM   3986 O O   . VAL B 1 165 ? 139.273 163.214 134.034 1.00 211.85 ?  165  VAL B O   1 
ATOM   3987 C CB  . VAL B 1 165 ? 137.509 165.033 135.914 1.00 211.85 ?  165  VAL B CB  1 
ATOM   3988 C CG1 . VAL B 1 165 ? 136.262 165.084 136.778 1.00 211.85 ?  165  VAL B CG1 1 
ATOM   3989 C CG2 . VAL B 1 165 ? 138.412 166.229 136.172 1.00 211.85 ?  165  VAL B CG2 1 
ATOM   3990 N N   . THR B 1 166 ? 140.648 163.887 135.666 1.00 246.51 ?  166  THR B N   1 
ATOM   3991 C CA  . THR B 1 166 ? 141.812 163.878 134.787 1.00 246.51 ?  166  THR B CA  1 
ATOM   3992 C C   . THR B 1 166 ? 142.381 162.493 134.591 1.00 246.51 ?  166  THR B C   1 
ATOM   3993 O O   . THR B 1 166 ? 142.848 162.175 133.512 1.00 246.51 ?  166  THR B O   1 
ATOM   3994 C CB  . THR B 1 166 ? 142.933 164.814 135.270 1.00 246.51 ?  166  THR B CB  1 
ATOM   3995 O OG1 . THR B 1 166 ? 143.324 164.457 136.600 1.00 246.51 ?  166  THR B OG1 1 
ATOM   3996 C CG2 . THR B 1 166 ? 142.473 166.262 135.236 1.00 246.51 ?  166  THR B CG2 1 
ATOM   3997 N N   . PHE B 1 167 ? 142.359 161.665 135.624 1.00 237.22 ?  167  PHE B N   1 
ATOM   3998 C CA  . PHE B 1 167 ? 142.814 160.290 135.457 1.00 237.22 ?  167  PHE B CA  1 
ATOM   3999 C C   . PHE B 1 167 ? 142.082 159.607 134.295 1.00 237.22 ?  167  PHE B C   1 
ATOM   4000 O O   . PHE B 1 167 ? 142.730 159.122 133.368 1.00 237.22 ?  167  PHE B O   1 
ATOM   4001 C CB  . PHE B 1 167 ? 142.703 159.508 136.768 1.00 237.22 ?  167  PHE B CB  1 
ATOM   4002 C CG  . PHE B 1 167 ? 143.611 158.318 136.850 1.00 237.22 ?  167  PHE B CG  1 
ATOM   4003 C CD1 . PHE B 1 167 ? 143.253 157.114 136.270 1.00 237.22 ?  167  PHE B CD1 1 
ATOM   4004 C CD2 . PHE B 1 167 ? 144.814 158.400 137.527 1.00 237.22 ?  167  PHE B CD2 1 
ATOM   4005 C CE1 . PHE B 1 167 ? 144.084 156.018 136.351 1.00 237.22 ?  167  PHE B CE1 1 
ATOM   4006 C CE2 . PHE B 1 167 ? 145.651 157.306 137.613 1.00 237.22 ?  167  PHE B CE2 1 
ATOM   4007 C CZ  . PHE B 1 167 ? 145.286 156.113 137.023 1.00 237.22 ?  167  PHE B CZ  1 
ATOM   4008 N N   . PRO B 1 168 ? 140.733 159.585 134.312 1.00 249.60 ?  168  PRO B N   1 
ATOM   4009 C CA  . PRO B 1 168 ? 140.076 158.997 133.144 1.00 249.60 ?  168  PRO B CA  1 
ATOM   4010 C C   . PRO B 1 168 ? 140.348 159.768 131.861 1.00 249.60 ?  168  PRO B C   1 
ATOM   4011 O O   . PRO B 1 168 ? 140.532 159.145 130.826 1.00 249.60 ?  168  PRO B O   1 
ATOM   4012 C CB  . PRO B 1 168 ? 138.597 159.105 133.490 1.00 249.60 ?  168  PRO B CB  1 
ATOM   4013 C CG  . PRO B 1 168 ? 138.554 159.125 134.965 1.00 249.60 ?  168  PRO B CG  1 
ATOM   4014 C CD  . PRO B 1 168 ? 139.749 159.932 135.351 1.00 249.60 ?  168  PRO B CD  1 
ATOM   4015 N N   . LEU B 1 169 ? 140.368 161.095 131.922 1.00 300.80 ?  169  LEU B N   1 
ATOM   4016 C CA  . LEU B 1 169 ? 140.612 161.906 130.736 1.00 300.80 ?  169  LEU B CA  1 
ATOM   4017 C C   . LEU B 1 169 ? 141.915 161.519 130.083 1.00 300.80 ?  169  LEU B C   1 
ATOM   4018 O O   . LEU B 1 169 ? 141.940 161.208 128.902 1.00 300.80 ?  169  LEU B O   1 
ATOM   4019 C CB  . LEU B 1 169 ? 140.636 163.393 131.076 1.00 300.80 ?  169  LEU B CB  1 
ATOM   4020 C CG  . LEU B 1 169 ? 139.395 164.194 130.691 1.00 300.80 ?  169  LEU B CG  1 
ATOM   4021 C CD1 . LEU B 1 169 ? 139.396 165.546 131.386 1.00 300.80 ?  169  LEU B CD1 1 
ATOM   4022 C CD2 . LEU B 1 169 ? 139.342 164.365 129.185 1.00 300.80 ?  169  LEU B CD2 1 
ATOM   4023 N N   . VAL B 1 170 ? 142.998 161.531 130.849 1.00 303.99 ?  170  VAL B N   1 
ATOM   4024 C CA  . VAL B 1 170 ? 144.305 161.186 130.308 1.00 303.99 ?  170  VAL B CA  1 
ATOM   4025 C C   . VAL B 1 170 ? 144.264 159.809 129.679 1.00 303.99 ?  170  VAL B C   1 
ATOM   4026 O O   . VAL B 1 170 ? 144.677 159.637 128.540 1.00 303.99 ?  170  VAL B O   1 
ATOM   4027 C CB  . VAL B 1 170 ? 145.396 161.240 131.392 1.00 303.99 ?  170  VAL B CB  1 
ATOM   4028 C CG1 . VAL B 1 170 ? 146.678 160.577 130.911 1.00 303.99 ?  170  VAL B CG1 1 
ATOM   4029 C CG2 . VAL B 1 170 ? 145.666 162.681 131.791 1.00 303.99 ?  170  VAL B CG2 1 
ATOM   4030 N N   . LEU B 1 171 ? 143.731 158.833 130.398 1.00 296.97 ?  171  LEU B N   1 
ATOM   4031 C CA  . LEU B 1 171 ? 143.709 157.470 129.888 1.00 296.97 ?  171  LEU B CA  1 
ATOM   4032 C C   . LEU B 1 171 ? 142.892 157.305 128.611 1.00 296.97 ?  171  LEU B C   1 
ATOM   4033 O O   . LEU B 1 171 ? 143.309 156.603 127.700 1.00 296.97 ?  171  LEU B O   1 
ATOM   4034 C CB  . LEU B 1 171 ? 143.233 156.509 130.972 1.00 296.97 ?  171  LEU B CB  1 
ATOM   4035 C CG  . LEU B 1 171 ? 144.311 156.161 131.995 1.00 296.97 ?  171  LEU B CG  1 
ATOM   4036 C CD1 . LEU B 1 171 ? 143.977 154.851 132.679 1.00 296.97 ?  171  LEU B CD1 1 
ATOM   4037 C CD2 . LEU B 1 171 ? 145.672 156.074 131.325 1.00 296.97 ?  171  LEU B CD2 1 
ATOM   4038 N N   . ILE B 1 172 ? 141.740 157.958 128.532 1.00 290.81 ?  172  ILE B N   1 
ATOM   4039 C CA  . ILE B 1 172 ? 140.894 157.852 127.346 1.00 290.81 ?  172  ILE B CA  1 
ATOM   4040 C C   . ILE B 1 172 ? 141.495 158.632 126.191 1.00 290.81 ?  172  ILE B C   1 
ATOM   4041 O O   . ILE B 1 172 ? 141.490 158.171 125.054 1.00 290.81 ?  172  ILE B O   1 
ATOM   4042 C CB  . ILE B 1 172 ? 139.452 158.321 127.622 1.00 290.81 ?  172  ILE B CB  1 
ATOM   4043 C CG1 . ILE B 1 172 ? 138.763 157.366 128.595 1.00 290.81 ?  172  ILE B CG1 1 
ATOM   4044 C CG2 . ILE B 1 172 ? 138.651 158.405 126.334 1.00 290.81 ?  172  ILE B CG2 1 
ATOM   4045 C CD1 . ILE B 1 172 ? 138.612 155.959 128.064 1.00 290.81 ?  172  ILE B CD1 1 
ATOM   4046 N N   . LEU B 1 173 ? 142.045 159.804 126.477 1.00 334.45 ?  173  LEU B N   1 
ATOM   4047 C CA  . LEU B 1 173 ? 142.700 160.579 125.433 1.00 334.45 ?  173  LEU B CA  1 
ATOM   4048 C C   . LEU B 1 173 ? 143.878 159.789 124.902 1.00 334.45 ?  173  LEU B C   1 
ATOM   4049 O O   . LEU B 1 173 ? 144.121 159.775 123.703 1.00 334.45 ?  173  LEU B O   1 
ATOM   4050 C CB  . LEU B 1 173 ? 143.165 161.930 125.965 1.00 334.45 ?  173  LEU B CB  1 
ATOM   4051 C CG  . LEU B 1 173 ? 142.358 163.152 125.528 1.00 334.45 ?  173  LEU B CG  1 
ATOM   4052 C CD1 . LEU B 1 173 ? 140.938 162.761 125.158 1.00 334.45 ?  173  LEU B CD1 1 
ATOM   4053 C CD2 . LEU B 1 173 ? 142.360 164.207 126.621 1.00 334.45 ?  173  LEU B CD2 1 
ATOM   4054 N N   . PHE B 1 174 ? 144.604 159.117 125.788 1.00 322.85 ?  174  PHE B N   1 
ATOM   4055 C CA  . PHE B 1 174 ? 145.717 158.284 125.359 1.00 322.85 ?  174  PHE B CA  1 
ATOM   4056 C C   . PHE B 1 174 ? 145.222 157.145 124.489 1.00 322.85 ?  174  PHE B C   1 
ATOM   4057 O O   . PHE B 1 174 ? 145.786 156.893 123.437 1.00 322.85 ?  174  PHE B O   1 
ATOM   4058 C CB  . PHE B 1 174 ? 146.480 157.731 126.558 1.00 322.85 ?  174  PHE B CB  1 
ATOM   4059 C CG  . PHE B 1 174 ? 147.494 156.687 126.200 1.00 322.85 ?  174  PHE B CG  1 
ATOM   4060 C CD1 . PHE B 1 174 ? 148.632 157.024 125.488 1.00 322.85 ?  174  PHE B CD1 1 
ATOM   4061 C CD2 . PHE B 1 174 ? 147.307 155.367 126.570 1.00 322.85 ?  174  PHE B CD2 1 
ATOM   4062 C CE1 . PHE B 1 174 ? 149.566 156.065 125.152 1.00 322.85 ?  174  PHE B CE1 1 
ATOM   4063 C CE2 . PHE B 1 174 ? 148.236 154.404 126.237 1.00 322.85 ?  174  PHE B CE2 1 
ATOM   4064 C CZ  . PHE B 1 174 ? 149.368 154.753 125.529 1.00 322.85 ?  174  PHE B CZ  1 
ATOM   4065 N N   . SER B 1 175 ? 144.174 156.452 124.919 1.00 290.57 ?  175  SER B N   1 
ATOM   4066 C CA  . SER B 1 175 ? 143.609 155.377 124.116 1.00 290.57 ?  175  SER B CA  1 
ATOM   4067 C C   . SER B 1 175 ? 143.332 155.872 122.718 1.00 290.57 ?  175  SER B C   1 
ATOM   4068 O O   . SER B 1 175 ? 143.775 155.270 121.744 1.00 290.57 ?  175  SER B O   1 
ATOM   4069 C CB  . SER B 1 175 ? 142.308 154.868 124.727 1.00 290.57 ?  175  SER B CB  1 
ATOM   4070 O OG  . SER B 1 175 ? 142.480 154.485 126.075 1.00 290.57 ?  175  SER B OG  1 
ATOM   4071 N N   . ALA B 1 176 ? 142.603 156.975 122.612 1.00 295.67 ?  176  ALA B N   1 
ATOM   4072 C CA  . ALA B 1 176 ? 142.262 157.525 121.310 1.00 295.67 ?  176  ALA B CA  1 
ATOM   4073 C C   . ALA B 1 176 ? 143.501 157.871 120.508 1.00 295.67 ?  176  ALA B C   1 
ATOM   4074 O O   . ALA B 1 176 ? 143.620 157.474 119.355 1.00 295.67 ?  176  ALA B O   1 
ATOM   4075 C CB  . ALA B 1 176 ? 141.379 158.747 121.478 1.00 295.67 ?  176  ALA B CB  1 
ATOM   4076 N N   . LEU B 1 177 ? 144.426 158.606 121.112 1.00 323.50 ?  177  LEU B N   1 
ATOM   4077 C CA  . LEU B 1 177 ? 145.636 159.011 120.414 1.00 323.50 ?  177  LEU B CA  1 
ATOM   4078 C C   . LEU B 1 177 ? 146.440 157.813 119.955 1.00 323.50 ?  177  LEU B C   1 
ATOM   4079 O O   . LEU B 1 177 ? 146.862 157.753 118.806 1.00 323.50 ?  177  LEU B O   1 
ATOM   4080 C CB  . LEU B 1 177 ? 146.497 159.895 121.308 1.00 323.50 ?  177  LEU B CB  1 
ATOM   4081 C CG  . LEU B 1 177 ? 147.297 160.982 120.595 1.00 323.50 ?  177  LEU B CG  1 
ATOM   4082 C CD1 . LEU B 1 177 ? 146.495 161.574 119.446 1.00 323.50 ?  177  LEU B CD1 1 
ATOM   4083 C CD2 . LEU B 1 177 ? 147.722 162.063 121.575 1.00 323.50 ?  177  LEU B CD2 1 
ATOM   4084 N N   . PHE B 1 178 ? 146.657 156.859 120.849 1.00 305.78 ?  178  PHE B N   1 
ATOM   4085 C CA  . PHE B 1 178 ? 147.414 155.667 120.500 1.00 305.78 ?  178  PHE B CA  1 
ATOM   4086 C C   . PHE B 1 178 ? 146.787 154.991 119.300 1.00 305.78 ?  178  PHE B C   1 
ATOM   4087 O O   . PHE B 1 178 ? 147.459 154.738 118.313 1.00 305.78 ?  178  PHE B O   1 
ATOM   4088 C CB  . PHE B 1 178 ? 147.473 154.696 121.675 1.00 305.78 ?  178  PHE B CB  1 
ATOM   4089 C CG  . PHE B 1 178 ? 148.599 153.712 121.589 1.00 305.78 ?  178  PHE B CG  1 
ATOM   4090 C CD1 . PHE B 1 178 ? 149.903 154.116 121.808 1.00 305.78 ?  178  PHE B CD1 1 
ATOM   4091 C CD2 . PHE B 1 178 ? 148.355 152.386 121.289 1.00 305.78 ?  178  PHE B CD2 1 
ATOM   4092 C CE1 . PHE B 1 178 ? 150.944 153.214 121.731 1.00 305.78 ?  178  PHE B CE1 1 
ATOM   4093 C CE2 . PHE B 1 178 ? 149.391 151.479 121.206 1.00 305.78 ?  178  PHE B CE2 1 
ATOM   4094 C CZ  . PHE B 1 178 ? 150.688 151.892 121.430 1.00 305.78 ?  178  PHE B CZ  1 
ATOM   4095 N N   . CYS B 1 179 ? 145.497 154.703 119.379 1.00 247.55 ?  179  CYS B N   1 
ATOM   4096 C CA  . CYS B 1 179 ? 144.808 154.080 118.263 1.00 247.55 ?  179  CYS B CA  1 
ATOM   4097 C C   . CYS B 1 179 ? 144.996 154.882 116.989 1.00 247.55 ?  179  CYS B C   1 
ATOM   4098 O O   . CYS B 1 179 ? 145.486 154.363 115.999 1.00 247.55 ?  179  CYS B O   1 
ATOM   4099 C CB  . CYS B 1 179 ? 143.327 153.925 118.574 1.00 247.55 ?  179  CYS B CB  1 
ATOM   4100 S SG  . CYS B 1 179 ? 142.909 152.308 119.246 1.00 247.55 ?  179  CYS B SG  1 
ATOM   4101 N N   . HIS B 1 180 ? 144.630 156.154 117.013 1.00 321.14 ?  180  HIS B N   1 
ATOM   4102 C CA  . HIS B 1 180 ? 144.791 157.004 115.842 1.00 321.14 ?  180  HIS B CA  1 
ATOM   4103 C C   . HIS B 1 180 ? 146.168 156.866 115.225 1.00 321.14 ?  180  HIS B C   1 
ATOM   4104 O O   . HIS B 1 180 ? 146.292 156.647 114.022 1.00 321.14 ?  180  HIS B O   1 
ATOM   4105 C CB  . HIS B 1 180 ? 144.549 158.465 116.215 1.00 321.14 ?  180  HIS B CB  1 
ATOM   4106 C CG  . HIS B 1 180 ? 144.515 159.389 115.040 1.00 321.14 ?  180  HIS B CG  1 
ATOM   4107 N ND1 . HIS B 1 180 ? 143.842 159.087 113.876 1.00 321.14 ?  180  HIS B ND1 1 
ATOM   4108 C CD2 . HIS B 1 180 ? 145.071 160.608 114.848 1.00 321.14 ?  180  HIS B CD2 1 
ATOM   4109 C CE1 . HIS B 1 180 ? 143.985 160.080 113.017 1.00 321.14 ?  180  HIS B CE1 1 
ATOM   4110 N NE2 . HIS B 1 180 ? 144.726 161.016 113.582 1.00 321.14 ?  180  HIS B NE2 1 
ATOM   4111 N N   . LEU B 1 181 ? 147.207 156.990 116.041 1.00 330.88 ?  181  LEU B N   1 
ATOM   4112 C CA  . LEU B 1 181 ? 148.569 156.929 115.527 1.00 330.88 ?  181  LEU B CA  1 
ATOM   4113 C C   . LEU B 1 181 ? 148.944 155.546 115.025 1.00 330.88 ?  181  LEU B C   1 
ATOM   4114 O O   . LEU B 1 181 ? 149.346 155.395 113.875 1.00 330.88 ?  181  LEU B O   1 
ATOM   4115 C CB  . LEU B 1 181 ? 149.557 157.375 116.602 1.00 330.88 ?  181  LEU B CB  1 
ATOM   4116 C CG  . LEU B 1 181 ? 150.007 158.837 116.580 1.00 330.88 ?  181  LEU B CG  1 
ATOM   4117 C CD1 . LEU B 1 181 ? 149.235 159.648 115.549 1.00 330.88 ?  181  LEU B CD1 1 
ATOM   4118 C CD2 . LEU B 1 181 ? 149.879 159.457 117.961 1.00 330.88 ?  181  LEU B CD2 1 
ATOM   4119 N N   . ILE B 1 182 ? 148.822 154.537 115.876 1.00 337.23 ?  182  ILE B N   1 
ATOM   4120 C CA  . ILE B 1 182 ? 149.218 153.187 115.492 1.00 337.23 ?  182  ILE B CA  1 
ATOM   4121 C C   . ILE B 1 182 ? 148.302 152.585 114.434 1.00 337.23 ?  182  ILE B C   1 
ATOM   4122 O O   . ILE B 1 182 ? 148.697 152.444 113.277 1.00 337.23 ?  182  ILE B O   1 
ATOM   4123 C CB  . ILE B 1 182 ? 149.307 152.258 116.714 1.00 337.23 ?  182  ILE B CB  1 
ATOM   4124 C CG1 . ILE B 1 182 ? 150.146 152.912 117.807 1.00 337.23 ?  182  ILE B CG1 1 
ATOM   4125 C CG2 . ILE B 1 182 ? 149.929 150.926 116.330 1.00 337.23 ?  182  ILE B CG2 1 
ATOM   4126 C CD1 . ILE B 1 182 ? 151.635 152.818 117.568 1.00 337.23 ?  182  ILE B CD1 1 
ATOM   4127 N N   . SER B 1 183 ? 147.084 152.229 114.818 1.00 277.75 ?  183  SER B N   1 
ATOM   4128 C CA  . SER B 1 183 ? 146.146 151.648 113.871 1.00 277.75 ?  183  SER B CA  1 
ATOM   4129 C C   . SER B 1 183 ? 144.760 152.221 114.075 1.00 277.75 ?  183  SER B C   1 
ATOM   4130 O O   . SER B 1 183 ? 144.090 151.898 115.053 1.00 277.75 ?  183  SER B O   1 
ATOM   4131 C CB  . SER B 1 183 ? 146.110 150.135 114.021 1.00 277.75 ?  183  SER B CB  1 
ATOM   4132 O OG  . SER B 1 183 ? 144.839 149.617 113.682 1.00 277.75 ?  183  SER B OG  1 
ATOM   4133 N N   . PRO B 1 184 ? 144.316 153.084 113.153 1.00 290.93 ?  184  PRO B N   1 
ATOM   4134 C CA  . PRO B 1 184 ? 143.003 153.723 113.287 1.00 290.93 ?  184  PRO B CA  1 
ATOM   4135 C C   . PRO B 1 184 ? 141.837 152.776 113.041 1.00 290.93 ?  184  PRO B C   1 
ATOM   4136 O O   . PRO B 1 184 ? 140.691 153.210 113.108 1.00 290.93 ?  184  PRO B O   1 
ATOM   4137 C CB  . PRO B 1 184 ? 143.034 154.805 112.210 1.00 290.93 ?  184  PRO B CB  1 
ATOM   4138 C CG  . PRO B 1 184 ? 144.006 154.305 111.198 1.00 290.93 ?  184  PRO B CG  1 
ATOM   4139 C CD  . PRO B 1 184 ? 145.054 153.565 111.973 1.00 290.93 ?  184  PRO B CD  1 
ATOM   4140 N N   . GLN B 1 185 ? 142.113 151.510 112.757 1.00 300.55 ?  185  GLN B N   1 
ATOM   4141 C CA  . GLN B 1 185 ? 141.050 150.536 112.571 1.00 300.55 ?  185  GLN B CA  1 
ATOM   4142 C C   . GLN B 1 185 ? 140.928 149.681 113.815 1.00 300.55 ?  185  GLN B C   1 
ATOM   4143 O O   . GLN B 1 185 ? 140.160 148.732 113.848 1.00 300.55 ?  185  GLN B O   1 
ATOM   4144 C CB  . GLN B 1 185 ? 141.305 149.665 111.338 1.00 300.55 ?  185  GLN B CB  1 
ATOM   4145 C CG  . GLN B 1 185 ? 142.698 149.069 111.257 1.00 300.55 ?  185  GLN B CG  1 
ATOM   4146 C CD  . GLN B 1 185 ? 143.636 149.890 110.395 1.00 300.55 ?  185  GLN B CD  1 
ATOM   4147 O OE1 . GLN B 1 185 ? 143.207 150.787 109.670 1.00 300.55 ?  185  GLN B OE1 1 
ATOM   4148 N NE2 . GLN B 1 185 ? 144.927 149.588 110.472 1.00 300.55 ?  185  GLN B NE2 1 
ATOM   4149 N N   . ALA B 1 186 ? 141.676 150.026 114.854 1.00 285.83 ?  186  ALA B N   1 
ATOM   4150 C CA  . ALA B 1 186 ? 141.585 149.288 116.104 1.00 285.83 ?  186  ALA B CA  1 
ATOM   4151 C C   . ALA B 1 186 ? 140.625 149.971 117.057 1.00 285.83 ?  186  ALA B C   1 
ATOM   4152 O O   . ALA B 1 186 ? 140.811 149.917 118.267 1.00 285.83 ?  186  ALA B O   1 
ATOM   4153 C CB  . ALA B 1 186 ? 142.952 149.159 116.742 1.00 285.83 ?  186  ALA B CB  1 
ATOM   4154 N N   . VAL B 1 187 ? 139.598 150.617 116.519 1.00 285.09 ?  187  VAL B N   1 
ATOM   4155 C CA  . VAL B 1 187 ? 138.620 151.297 117.353 1.00 285.09 ?  187  VAL B CA  1 
ATOM   4156 C C   . VAL B 1 187 ? 137.240 150.682 117.206 1.00 285.09 ?  187  VAL B C   1 
ATOM   4157 O O   . VAL B 1 187 ? 136.954 150.027 116.205 1.00 285.09 ?  187  VAL B O   1 
ATOM   4158 C CB  . VAL B 1 187 ? 138.532 152.798 117.009 1.00 285.09 ?  187  VAL B CB  1 
ATOM   4159 C CG1 . VAL B 1 187 ? 139.825 153.507 117.369 1.00 285.09 ?  187  VAL B CG1 1 
ATOM   4160 C CG2 . VAL B 1 187 ? 138.210 152.996 115.537 1.00 285.09 ?  187  VAL B CG2 1 
ATOM   4161 N N   . GLY B 1 188 ? 136.388 150.864 118.205 1.00 258.62 ?  188  GLY B N   1 
ATOM   4162 C CA  . GLY B 1 188 ? 135.018 150.388 118.105 1.00 258.62 ?  188  GLY B CA  1 
ATOM   4163 C C   . GLY B 1 188 ? 134.752 148.905 117.999 1.00 258.62 ?  188  GLY B C   1 
ATOM   4164 O O   . GLY B 1 188 ? 134.388 148.432 116.921 1.00 258.62 ?  188  GLY B O   1 
ATOM   4165 N N   . SER B 1 189 ? 134.916 148.172 119.096 1.00 249.74 ?  189  SER B N   1 
ATOM   4166 C CA  . SER B 1 189 ? 134.609 146.738 119.119 1.00 249.74 ?  189  SER B CA  1 
ATOM   4167 C C   . SER B 1 189 ? 135.341 145.904 118.086 1.00 249.74 ?  189  SER B C   1 
ATOM   4168 O O   . SER B 1 189 ? 136.347 146.324 117.526 1.00 249.74 ?  189  SER B O   1 
ATOM   4169 C CB  . SER B 1 189 ? 133.097 146.506 119.009 1.00 249.74 ?  189  SER B CB  1 
ATOM   4170 O OG  . SER B 1 189 ? 132.659 145.480 119.880 1.00 249.74 ?  189  SER B OG  1 
ATOM   4171 N N   . GLY B 1 190 ? 134.844 144.703 117.845 1.00 248.75 ?  190  GLY B N   1 
ATOM   4172 C CA  . GLY B 1 190 ? 135.466 143.836 116.870 1.00 248.75 ?  190  GLY B CA  1 
ATOM   4173 C C   . GLY B 1 190 ? 134.413 142.918 116.320 1.00 248.75 ?  190  GLY B C   1 
ATOM   4174 O O   . GLY B 1 190 ? 134.484 142.530 115.165 1.00 248.75 ?  190  GLY B O   1 
ATOM   4175 N N   . ILE B 1 191 ? 133.427 142.579 117.142 1.00 237.15 ?  191  ILE B N   1 
ATOM   4176 C CA  . ILE B 1 191 ? 132.332 141.724 116.696 1.00 237.15 ?  191  ILE B CA  1 
ATOM   4177 C C   . ILE B 1 191 ? 131.629 142.192 115.417 1.00 237.15 ?  191  ILE B C   1 
ATOM   4178 O O   . ILE B 1 191 ? 131.398 141.382 114.524 1.00 237.15 ?  191  ILE B O   1 
ATOM   4179 C CB  . ILE B 1 191 ? 131.299 141.503 117.815 1.00 237.15 ?  191  ILE B CB  1 
ATOM   4180 C CG1 . ILE B 1 191 ? 132.003 141.264 119.148 1.00 237.15 ?  191  ILE B CG1 1 
ATOM   4181 C CG2 . ILE B 1 191 ? 130.386 140.340 117.478 1.00 237.15 ?  191  ILE B CG2 1 
ATOM   4182 C CD1 . ILE B 1 191 ? 131.534 140.022 119.868 1.00 237.15 ?  191  ILE B CD1 1 
ATOM   4183 N N   . PRO B 1 192 ? 131.285 143.492 115.306 1.00 265.78 ?  192  PRO B N   1 
ATOM   4184 C CA  . PRO B 1 192 ? 130.659 143.874 114.036 1.00 265.78 ?  192  PRO B CA  1 
ATOM   4185 C C   . PRO B 1 192 ? 131.531 143.553 112.832 1.00 265.78 ?  192  PRO B C   1 
ATOM   4186 O O   . PRO B 1 192 ? 131.055 142.973 111.856 1.00 265.78 ?  192  PRO B O   1 
ATOM   4187 C CB  . PRO B 1 192 ? 130.516 145.388 114.166 1.00 265.78 ?  192  PRO B CB  1 
ATOM   4188 C CG  . PRO B 1 192 ? 130.414 145.632 115.623 1.00 265.78 ?  192  PRO B CG  1 
ATOM   4189 C CD  . PRO B 1 192 ? 131.303 144.616 116.262 1.00 265.78 ?  192  PRO B CD  1 
ATOM   4190 N N   . GLU B 1 193 ? 132.802 143.916 112.897 1.00 275.33 ?  193  GLU B N   1 
ATOM   4191 C CA  . GLU B 1 193 ? 133.689 143.701 111.767 1.00 275.33 ?  193  GLU B CA  1 
ATOM   4192 C C   . GLU B 1 193 ? 134.106 142.247 111.607 1.00 275.33 ?  193  GLU B C   1 
ATOM   4193 O O   . GLU B 1 193 ? 134.442 141.824 110.509 1.00 275.33 ?  193  GLU B O   1 
ATOM   4194 C CB  . GLU B 1 193 ? 134.905 144.609 111.890 1.00 275.33 ?  193  GLU B CB  1 
ATOM   4195 C CG  . GLU B 1 193 ? 134.564 146.091 111.840 1.00 275.33 ?  193  GLU B CG  1 
ATOM   4196 C CD  . GLU B 1 193 ? 134.631 146.764 113.199 1.00 275.33 ?  193  GLU B CD  1 
ATOM   4197 O OE1 . GLU B 1 193 ? 134.038 146.239 114.165 1.00 275.33 ?  193  GLU B OE1 1 
ATOM   4198 O OE2 . GLU B 1 193 ? 135.286 147.821 113.306 1.00 275.33 -1 193  GLU B OE2 1 
ATOM   4199 N N   . MET B 1 194 ? 134.077 141.476 112.685 1.00 255.21 ?  194  MET B N   1 
ATOM   4200 C CA  . MET B 1 194 ? 134.391 140.058 112.589 1.00 255.21 ?  194  MET B CA  1 
ATOM   4201 C C   . MET B 1 194 ? 133.269 139.360 111.862 1.00 255.21 ?  194  MET B C   1 
ATOM   4202 O O   . MET B 1 194 ? 133.514 138.432 111.108 1.00 255.21 ?  194  MET B O   1 
ATOM   4203 C CB  . MET B 1 194 ? 134.574 139.438 113.969 1.00 255.21 ?  194  MET B CB  1 
ATOM   4204 C CG  . MET B 1 194 ? 136.025 139.239 114.364 1.00 255.21 ?  194  MET B CG  1 
ATOM   4205 S SD  . MET B 1 194 ? 136.996 138.498 113.041 1.00 255.21 ?  194  MET B SD  1 
ATOM   4206 C CE  . MET B 1 194 ? 138.129 139.835 112.689 1.00 255.21 ?  194  MET B CE  1 
ATOM   4207 N N   . LYS B 1 195 ? 132.036 139.799 112.085 1.00 246.75 ?  195  LYS B N   1 
ATOM   4208 C CA  . LYS B 1 195 ? 130.904 139.231 111.372 1.00 246.75 ?  195  LYS B CA  1 
ATOM   4209 C C   . LYS B 1 195 ? 131.136 139.436 109.894 1.00 246.75 ?  195  LYS B C   1 
ATOM   4210 O O   . LYS B 1 195 ? 130.975 138.512 109.102 1.00 246.75 ?  195  LYS B O   1 
ATOM   4211 C CB  . LYS B 1 195 ? 129.626 139.947 111.779 1.00 246.75 ?  195  LYS B CB  1 
ATOM   4212 C CG  . LYS B 1 195 ? 128.714 139.161 112.698 1.00 246.75 ?  195  LYS B CG  1 
ATOM   4213 C CD  . LYS B 1 195 ? 127.530 140.011 113.127 1.00 246.75 ?  195  LYS B CD  1 
ATOM   4214 C CE  . LYS B 1 195 ? 126.276 139.168 113.277 1.00 246.75 ?  195  LYS B CE  1 
ATOM   4215 N NZ  . LYS B 1 195 ? 126.531 137.742 112.933 1.00 246.75 1  195  LYS B NZ  1 
ATOM   4216 N N   . THR B 1 196 ? 131.522 140.650 109.518 1.00 271.27 ?  196  THR B N   1 
ATOM   4217 C CA  . THR B 1 196 ? 131.801 140.954 108.120 1.00 271.27 ?  196  THR B CA  1 
ATOM   4218 C C   . THR B 1 196 ? 132.914 140.074 107.562 1.00 271.27 ?  196  THR B C   1 
ATOM   4219 O O   . THR B 1 196 ? 132.762 139.479 106.497 1.00 271.27 ?  196  THR B O   1 
ATOM   4220 C CB  . THR B 1 196 ? 132.189 142.435 107.974 1.00 271.27 ?  196  THR B CB  1 
ATOM   4221 O OG1 . THR B 1 196 ? 131.189 143.249 108.597 1.00 271.27 ?  196  THR B OG1 1 
ATOM   4222 C CG2 . THR B 1 196 ? 132.317 142.830 106.519 1.00 271.27 ?  196  THR B CG2 1 
ATOM   4223 N N   . ILE B 1 197 ? 134.034 139.982 108.275 1.00 285.13 ?  197  ILE B N   1 
ATOM   4224 C CA  . ILE B 1 197 ? 135.165 139.167 107.822 1.00 285.13 ?  197  ILE B CA  1 
ATOM   4225 C C   . ILE B 1 197 ? 134.781 137.698 107.697 1.00 285.13 ?  197  ILE B C   1 
ATOM   4226 O O   . ILE B 1 197 ? 135.116 137.047 106.709 1.00 285.13 ?  197  ILE B O   1 
ATOM   4227 C CB  . ILE B 1 197 ? 136.385 139.327 108.753 1.00 285.13 ?  197  ILE B CB  1 
ATOM   4228 C CG1 . ILE B 1 197 ? 136.950 140.741 108.642 1.00 285.13 ?  197  ILE B CG1 1 
ATOM   4229 C CG2 . ILE B 1 197 ? 137.474 138.323 108.416 1.00 285.13 ?  197  ILE B CG2 1 
ATOM   4230 C CD1 . ILE B 1 197 ? 138.446 140.819 108.842 1.00 285.13 ?  197  ILE B CD1 1 
ATOM   4231 N N   . LEU B 1 198 ? 134.052 137.179 108.676 1.00 250.77 ?  198  LEU B N   1 
ATOM   4232 C CA  . LEU B 1 198 ? 133.643 135.781 108.644 1.00 250.77 ?  198  LEU B CA  1 
ATOM   4233 C C   . LEU B 1 198 ? 132.688 135.505 107.493 1.00 250.77 ?  198  LEU B C   1 
ATOM   4234 O O   . LEU B 1 198 ? 132.563 134.365 107.052 1.00 250.77 ?  198  LEU B O   1 
ATOM   4235 C CB  . LEU B 1 198 ? 132.997 135.378 109.970 1.00 250.77 ?  198  LEU B CB  1 
ATOM   4236 C CG  . LEU B 1 198 ? 133.819 134.487 110.900 1.00 250.77 ?  198  LEU B CG  1 
ATOM   4237 C CD1 . LEU B 1 198 ? 135.227 134.317 110.359 1.00 250.77 ?  198  LEU B CD1 1 
ATOM   4238 C CD2 . LEU B 1 198 ? 133.849 135.054 112.309 1.00 250.77 ?  198  LEU B CD2 1 
ATOM   4239 N N   . ARG B 1 199 ? 132.015 136.539 106.998 1.00 291.37 ?  199  ARG B N   1 
ATOM   4240 C CA  . ARG B 1 199 ? 131.100 136.376 105.871 1.00 291.37 ?  199  ARG B CA  1 
ATOM   4241 C C   . ARG B 1 199 ? 131.833 136.565 104.557 1.00 291.37 ?  199  ARG B C   1 
ATOM   4242 O O   . ARG B 1 199 ? 131.219 136.882 103.542 1.00 291.37 ?  199  ARG B O   1 
ATOM   4243 C CB  . ARG B 1 199 ? 129.937 137.366 105.972 1.00 291.37 ?  199  ARG B CB  1 
ATOM   4244 C CG  . ARG B 1 199 ? 128.565 136.749 105.755 1.00 291.37 ?  199  ARG B CG  1 
ATOM   4245 C CD  . ARG B 1 199 ? 127.766 136.705 107.046 1.00 291.37 ?  199  ARG B CD  1 
ATOM   4246 N NE  . ARG B 1 199 ? 128.634 136.581 108.213 1.00 291.37 ?  199  ARG B NE  1 
ATOM   4247 C CZ  . ARG B 1 199 ? 128.202 136.399 109.455 1.00 291.37 ?  199  ARG B CZ  1 
ATOM   4248 N NH1 . ARG B 1 199 ? 126.904 136.323 109.708 1.00 291.37 1  199  ARG B NH1 1 
ATOM   4249 N NH2 . ARG B 1 199 ? 129.072 136.298 110.445 1.00 291.37 ?  199  ARG B NH2 1 
ATOM   4250 N N   . GLY B 1 200 ? 133.148 136.390 104.571 1.00 276.46 ?  200  GLY B N   1 
ATOM   4251 C CA  . GLY B 1 200 ? 133.921 136.494 103.349 1.00 276.46 ?  200  GLY B CA  1 
ATOM   4252 C C   . GLY B 1 200 ? 134.587 137.828 103.122 1.00 276.46 ?  200  GLY B C   1 
ATOM   4253 O O   . GLY B 1 200 ? 135.708 137.875 102.621 1.00 276.46 ?  200  GLY B O   1 
ATOM   4254 N N   . VAL B 1 201 ? 133.919 138.918 103.481 1.00 264.22 ?  201  VAL B N   1 
ATOM   4255 C CA  . VAL B 1 201 ? 134.471 140.239 103.196 1.00 264.22 ?  201  VAL B CA  1 
ATOM   4256 C C   . VAL B 1 201 ? 135.602 140.643 104.121 1.00 264.22 ?  201  VAL B C   1 
ATOM   4257 O O   . VAL B 1 201 ? 135.369 141.230 105.173 1.00 264.22 ?  201  VAL B O   1 
ATOM   4258 C CB  . VAL B 1 201 ? 133.392 141.328 103.231 1.00 264.22 ?  201  VAL B CB  1 
ATOM   4259 C CG1 . VAL B 1 201 ? 133.498 142.201 101.992 1.00 264.22 ?  201  VAL B CG1 1 
ATOM   4260 C CG2 . VAL B 1 201 ? 132.012 140.703 103.331 1.00 264.22 ?  201  VAL B CG2 1 
ATOM   4261 N N   . VAL B 1 202 ? 136.832 140.349 103.720 1.00 240.15 ?  202  VAL B N   1 
ATOM   4262 C CA  . VAL B 1 202 ? 137.981 140.738 104.521 1.00 240.15 ?  202  VAL B CA  1 
ATOM   4263 C C   . VAL B 1 202 ? 138.104 142.259 104.530 1.00 240.15 ?  202  VAL B C   1 
ATOM   4264 O O   . VAL B 1 202 ? 137.778 142.924 103.545 1.00 240.15 ?  202  VAL B O   1 
ATOM   4265 C CB  . VAL B 1 202 ? 139.274 140.051 104.024 1.00 240.15 ?  202  VAL B CB  1 
ATOM   4266 C CG1 . VAL B 1 202 ? 139.717 140.594 102.673 1.00 240.15 ?  202  VAL B CG1 1 
ATOM   4267 C CG2 . VAL B 1 202 ? 140.385 140.150 105.059 1.00 240.15 ?  202  VAL B CG2 1 
ATOM   4268 N N   . LEU B 1 203 ? 138.543 142.822 105.649 1.00 252.28 ?  203  LEU B N   1 
ATOM   4269 C CA  . LEU B 1 203 ? 138.638 144.272 105.754 1.00 252.28 ?  203  LEU B CA  1 
ATOM   4270 C C   . LEU B 1 203 ? 140.005 144.766 105.321 1.00 252.28 ?  203  LEU B C   1 
ATOM   4271 O O   . LEU B 1 203 ? 140.702 144.086 104.570 1.00 252.28 ?  203  LEU B O   1 
ATOM   4272 C CB  . LEU B 1 203 ? 138.317 144.730 107.176 1.00 252.28 ?  203  LEU B CB  1 
ATOM   4273 C CG  . LEU B 1 203 ? 136.901 145.271 107.385 1.00 252.28 ?  203  LEU B CG  1 
ATOM   4274 C CD1 . LEU B 1 203 ? 136.201 145.492 106.053 1.00 252.28 ?  203  LEU B CD1 1 
ATOM   4275 C CD2 . LEU B 1 203 ? 136.087 144.336 108.262 1.00 252.28 ?  203  LEU B CD2 1 
ATOM   4276 N N   . LYS B 1 204 ? 140.390 145.950 105.779 1.00 266.35 ?  204  LYS B N   1 
ATOM   4277 C CA  . LYS B 1 204 ? 141.670 146.521 105.372 1.00 266.35 ?  204  LYS B CA  1 
ATOM   4278 C C   . LYS B 1 204 ? 142.817 145.940 106.174 1.00 266.35 ?  204  LYS B C   1 
ATOM   4279 O O   . LYS B 1 204 ? 143.248 144.813 105.936 1.00 266.35 ?  204  LYS B O   1 
ATOM   4280 C CB  . LYS B 1 204 ? 141.651 148.039 105.534 1.00 266.35 ?  204  LYS B CB  1 
ATOM   4281 C CG  . LYS B 1 204 ? 142.133 148.798 104.308 1.00 266.35 ?  204  LYS B CG  1 
ATOM   4282 C CD  . LYS B 1 204 ? 141.944 147.976 103.043 1.00 266.35 ?  204  LYS B CD  1 
ATOM   4283 C CE  . LYS B 1 204 ? 141.062 148.701 102.039 1.00 266.35 ?  204  LYS B CE  1 
ATOM   4284 N NZ  . LYS B 1 204 ? 139.673 148.882 102.543 1.00 266.35 1  204  LYS B NZ  1 
ATOM   4285 N N   . GLU B 1 205 ? 143.326 146.714 107.122 1.00 287.44 ?  205  GLU B N   1 
ATOM   4286 C CA  . GLU B 1 205 ? 144.398 146.220 107.969 1.00 287.44 ?  205  GLU B CA  1 
ATOM   4287 C C   . GLU B 1 205 ? 143.818 145.852 109.319 1.00 287.44 ?  205  GLU B C   1 
ATOM   4288 O O   . GLU B 1 205 ? 144.357 146.227 110.358 1.00 287.44 ?  205  GLU B O   1 
ATOM   4289 C CB  . GLU B 1 205 ? 145.493 147.273 108.116 1.00 287.44 ?  205  GLU B CB  1 
ATOM   4290 C CG  . GLU B 1 205 ? 145.627 148.203 106.922 1.00 287.44 ?  205  GLU B CG  1 
ATOM   4291 C CD  . GLU B 1 205 ? 146.259 147.524 105.724 1.00 287.44 ?  205  GLU B CD  1 
ATOM   4292 O OE1 . GLU B 1 205 ? 147.361 146.954 105.874 1.00 287.44 ?  205  GLU B OE1 1 
ATOM   4293 O OE2 . GLU B 1 205 ? 145.653 147.558 104.632 1.00 287.44 -1 205  GLU B OE2 1 
ATOM   4294 N N   . TYR B 1 206 ? 142.714 145.115 109.308 1.00 270.14 ?  206  TYR B N   1 
ATOM   4295 C CA  . TYR B 1 206 ? 142.059 144.745 110.551 1.00 270.14 ?  206  TYR B CA  1 
ATOM   4296 C C   . TYR B 1 206 ? 142.844 143.717 111.344 1.00 270.14 ?  206  TYR B C   1 
ATOM   4297 O O   . TYR B 1 206 ? 143.115 143.922 112.522 1.00 270.14 ?  206  TYR B O   1 
ATOM   4298 C CB  . TYR B 1 206 ? 140.654 144.218 110.271 1.00 270.14 ?  206  TYR B CB  1 
ATOM   4299 C CG  . TYR B 1 206 ? 139.697 144.496 111.395 1.00 270.14 ?  206  TYR B CG  1 
ATOM   4300 C CD1 . TYR B 1 206 ? 139.536 145.783 111.880 1.00 270.14 ?  206  TYR B CD1 1 
ATOM   4301 C CD2 . TYR B 1 206 ? 138.968 143.476 111.982 1.00 270.14 ?  206  TYR B CD2 1 
ATOM   4302 C CE1 . TYR B 1 206 ? 138.668 146.049 112.916 1.00 270.14 ?  206  TYR B CE1 1 
ATOM   4303 C CE2 . TYR B 1 206 ? 138.097 143.732 113.022 1.00 270.14 ?  206  TYR B CE2 1 
ATOM   4304 C CZ  . TYR B 1 206 ? 137.956 145.023 113.484 1.00 270.14 ?  206  TYR B CZ  1 
ATOM   4305 O OH  . TYR B 1 206 ? 137.096 145.299 114.516 1.00 270.14 ?  206  TYR B OH  1 
ATOM   4306 N N   . LEU B 1 207 ? 143.220 142.614 110.710 1.00 249.20 ?  207  LEU B N   1 
ATOM   4307 C CA  . LEU B 1 207 ? 143.916 141.549 111.425 1.00 249.20 ?  207  LEU B CA  1 
ATOM   4308 C C   . LEU B 1 207 ? 145.426 141.684 111.333 1.00 249.20 ?  207  LEU B C   1 
ATOM   4309 O O   . LEU B 1 207 ? 146.116 140.712 111.040 1.00 249.20 ?  207  LEU B O   1 
ATOM   4310 C CB  . LEU B 1 207 ? 143.493 140.186 110.884 1.00 249.20 ?  207  LEU B CB  1 
ATOM   4311 C CG  . LEU B 1 207 ? 142.454 139.388 111.670 1.00 249.20 ?  207  LEU B CG  1 
ATOM   4312 C CD1 . LEU B 1 207 ? 141.760 140.259 112.701 1.00 249.20 ?  207  LEU B CD1 1 
ATOM   4313 C CD2 . LEU B 1 207 ? 141.440 138.771 110.722 1.00 249.20 ?  207  LEU B CD2 1 
ATOM   4314 N N   . THR B 1 208 ? 145.944 142.879 111.588 1.00 277.04 ?  208  THR B N   1 
ATOM   4315 C CA  . THR B 1 208 ? 147.380 143.105 111.510 1.00 277.04 ?  208  THR B CA  1 
ATOM   4316 C C   . THR B 1 208 ? 148.003 143.246 112.887 1.00 277.04 ?  208  THR B C   1 
ATOM   4317 O O   . THR B 1 208 ? 147.292 143.341 113.883 1.00 277.04 ?  208  THR B O   1 
ATOM   4318 C CB  . THR B 1 208 ? 147.711 144.358 110.688 1.00 277.04 ?  208  THR B CB  1 
ATOM   4319 O OG1 . THR B 1 208 ? 146.935 145.464 111.163 1.00 277.04 ?  208  THR B OG1 1 
ATOM   4320 C CG2 . THR B 1 208 ? 147.410 144.121 109.220 1.00 277.04 ?  208  THR B CG2 1 
ATOM   4321 N N   . MET B 1 209 ? 149.330 143.269 112.946 1.00 249.61 ?  209  MET B N   1 
ATOM   4322 C CA  . MET B 1 209 ? 150.022 143.369 114.225 1.00 249.61 ?  209  MET B CA  1 
ATOM   4323 C C   . MET B 1 209 ? 149.947 144.770 114.833 1.00 249.61 ?  209  MET B C   1 
ATOM   4324 O O   . MET B 1 209 ? 149.979 144.906 116.054 1.00 249.61 ?  209  MET B O   1 
ATOM   4325 C CB  . MET B 1 209 ? 151.478 142.922 114.097 1.00 249.61 ?  209  MET B CB  1 
ATOM   4326 C CG  . MET B 1 209 ? 151.758 141.545 114.671 1.00 249.61 ?  209  MET B CG  1 
ATOM   4327 S SD  . MET B 1 209 ? 150.847 141.202 116.188 1.00 249.61 ?  209  MET B SD  1 
ATOM   4328 C CE  . MET B 1 209 ? 151.975 141.850 117.419 1.00 249.61 ?  209  MET B CE  1 
ATOM   4329 N N   . LYS B 1 210 ? 149.848 145.813 114.006 1.00 257.56 ?  210  LYS B N   1 
ATOM   4330 C CA  . LYS B 1 210 ? 149.687 147.157 114.559 1.00 257.56 ?  210  LYS B CA  1 
ATOM   4331 C C   . LYS B 1 210 ? 148.360 147.244 115.271 1.00 257.56 ?  210  LYS B C   1 
ATOM   4332 O O   . LYS B 1 210 ? 148.251 147.847 116.339 1.00 257.56 ?  210  LYS B O   1 
ATOM   4333 C CB  . LYS B 1 210 ? 149.759 148.263 113.504 1.00 257.56 ?  210  LYS B CB  1 
ATOM   4334 C CG  . LYS B 1 210 ? 150.022 147.838 112.076 1.00 257.56 ?  210  LYS B CG  1 
ATOM   4335 C CD  . LYS B 1 210 ? 150.678 148.979 111.319 1.00 257.56 ?  210  LYS B CD  1 
ATOM   4336 C CE  . LYS B 1 210 ? 152.085 149.212 111.831 1.00 257.56 ?  210  LYS B CE  1 
ATOM   4337 N NZ  . LYS B 1 210 ? 152.695 150.508 111.411 1.00 257.56 1  210  LYS B NZ  1 
ATOM   4338 N N   . ALA B 1 211 ? 147.343 146.628 114.689 1.00 269.25 ?  211  ALA B N   1 
ATOM   4339 C CA  . ALA B 1 211 ? 146.028 146.670 115.289 1.00 269.25 ?  211  ALA B CA  1 
ATOM   4340 C C   . ALA B 1 211 ? 146.093 146.015 116.643 1.00 269.25 ?  211  ALA B C   1 
ATOM   4341 O O   . ALA B 1 211 ? 145.488 146.500 117.588 1.00 269.25 ?  211  ALA B O   1 
ATOM   4342 C CB  . ALA B 1 211 ? 145.017 145.981 114.396 1.00 269.25 ?  211  ALA B CB  1 
ATOM   4343 N N   . PHE B 1 212 ? 146.835 144.918 116.750 1.00 256.48 ?  212  PHE B N   1 
ATOM   4344 C CA  . PHE B 1 212 ? 146.996 144.244 118.029 1.00 256.48 ?  212  PHE B CA  1 
ATOM   4345 C C   . PHE B 1 212 ? 147.536 145.215 119.051 1.00 256.48 ?  212  PHE B C   1 
ATOM   4346 O O   . PHE B 1 212 ? 146.892 145.469 120.058 1.00 256.48 ?  212  PHE B O   1 
ATOM   4347 C CB  . PHE B 1 212 ? 147.947 143.062 117.893 1.00 256.48 ?  212  PHE B CB  1 
ATOM   4348 C CG  . PHE B 1 212 ? 147.917 142.119 119.057 1.00 256.48 ?  212  PHE B CG  1 
ATOM   4349 C CD1 . PHE B 1 212 ? 146.899 141.192 119.186 1.00 256.48 ?  212  PHE B CD1 1 
ATOM   4350 C CD2 . PHE B 1 212 ? 148.913 142.151 120.017 1.00 256.48 ?  212  PHE B CD2 1 
ATOM   4351 C CE1 . PHE B 1 212 ? 146.872 140.318 120.252 1.00 256.48 ?  212  PHE B CE1 1 
ATOM   4352 C CE2 . PHE B 1 212 ? 148.891 141.282 121.088 1.00 256.48 ?  212  PHE B CE2 1 
ATOM   4353 C CZ  . PHE B 1 212 ? 147.868 140.363 121.205 1.00 256.48 ?  212  PHE B CZ  1 
ATOM   4354 N N   . VAL B 1 213 ? 148.715 145.767 118.790 1.00 248.50 ?  213  VAL B N   1 
ATOM   4355 C CA  . VAL B 1 213 ? 149.325 146.709 119.721 1.00 248.50 ?  213  VAL B CA  1 
ATOM   4356 C C   . VAL B 1 213 ? 148.356 147.820 120.093 1.00 248.50 ?  213  VAL B C   1 
ATOM   4357 O O   . VAL B 1 213 ? 148.102 148.054 121.270 1.00 248.50 ?  213  VAL B O   1 
ATOM   4358 C CB  . VAL B 1 213 ? 150.615 147.313 119.144 1.00 248.50 ?  213  VAL B CB  1 
ATOM   4359 C CG1 . VAL B 1 213 ? 151.291 148.210 120.167 1.00 248.50 ?  213  VAL B CG1 1 
ATOM   4360 C CG2 . VAL B 1 213 ? 151.559 146.207 118.705 1.00 248.50 ?  213  VAL B CG2 1 
ATOM   4361 N N   . ALA B 1 214 ? 147.800 148.495 119.093 1.00 277.83 ?  214  ALA B N   1 
ATOM   4362 C CA  . ALA B 1 214 ? 146.864 149.578 119.353 1.00 277.83 ?  214  ALA B CA  1 
ATOM   4363 C C   . ALA B 1 214 ? 145.754 149.125 120.273 1.00 277.83 ?  214  ALA B C   1 
ATOM   4364 O O   . ALA B 1 214 ? 145.571 149.691 121.342 1.00 277.83 ?  214  ALA B O   1 
ATOM   4365 C CB  . ALA B 1 214 ? 146.289 150.109 118.056 1.00 277.83 ?  214  ALA B CB  1 
ATOM   4366 N N   . LYS B 1 215 ? 145.023 148.094 119.875 1.00 263.72 ?  215  LYS B N   1 
ATOM   4367 C CA  . LYS B 1 215 ? 143.898 147.637 120.674 1.00 263.72 ?  215  LYS B CA  1 
ATOM   4368 C C   . LYS B 1 215 ? 144.292 147.239 122.085 1.00 263.72 ?  215  LYS B C   1 
ATOM   4369 O O   . LYS B 1 215 ? 143.667 147.682 123.031 1.00 263.72 ?  215  LYS B O   1 
ATOM   4370 C CB  . LYS B 1 215 ? 143.158 146.494 119.987 1.00 263.72 ?  215  LYS B CB  1 
ATOM   4371 C CG  . LYS B 1 215 ? 141.677 146.447 120.313 1.00 263.72 ?  215  LYS B CG  1 
ATOM   4372 C CD  . LYS B 1 215 ? 140.853 146.311 119.049 1.00 263.72 ?  215  LYS B CD  1 
ATOM   4373 C CE  . LYS B 1 215 ? 139.474 146.926 119.205 1.00 263.72 ?  215  LYS B CE  1 
ATOM   4374 N NZ  . LYS B 1 215 ? 138.894 147.306 117.891 1.00 263.72 1  215  LYS B NZ  1 
ATOM   4375 N N   . VAL B 1 216 ? 145.322 146.417 122.247 1.00 243.99 ?  216  VAL B N   1 
ATOM   4376 C CA  . VAL B 1 216 ? 145.655 145.948 123.590 1.00 243.99 ?  216  VAL B CA  1 
ATOM   4377 C C   . VAL B 1 216 ? 146.003 147.099 124.524 1.00 243.99 ?  216  VAL B C   1 
ATOM   4378 O O   . VAL B 1 216 ? 145.466 147.181 125.621 1.00 243.99 ?  216  VAL B O   1 
ATOM   4379 C CB  . VAL B 1 216 ? 146.730 144.825 123.621 1.00 243.99 ?  216  VAL B CB  1 
ATOM   4380 C CG1 . VAL B 1 216 ? 146.264 143.614 122.834 1.00 243.99 ?  216  VAL B CG1 1 
ATOM   4381 C CG2 . VAL B 1 216 ? 148.089 145.294 123.130 1.00 243.99 ?  216  VAL B CG2 1 
ATOM   4382 N N   . VAL B 1 217 ? 146.860 148.010 124.085 1.00 240.87 ?  217  VAL B N   1 
ATOM   4383 C CA  . VAL B 1 217 ? 147.287 149.096 124.949 1.00 240.87 ?  217  VAL B CA  1 
ATOM   4384 C C   . VAL B 1 217 ? 146.132 150.037 125.212 1.00 240.87 ?  217  VAL B C   1 
ATOM   4385 O O   . VAL B 1 217 ? 145.869 150.408 126.355 1.00 240.87 ?  217  VAL B O   1 
ATOM   4386 C CB  . VAL B 1 217 ? 148.471 149.860 124.337 1.00 240.87 ?  217  VAL B CB  1 
ATOM   4387 C CG1 . VAL B 1 217 ? 148.910 150.991 125.250 1.00 240.87 ?  217  VAL B CG1 1 
ATOM   4388 C CG2 . VAL B 1 217 ? 149.633 148.912 124.090 1.00 240.87 ?  217  VAL B CG2 1 
ATOM   4389 N N   . ALA B 1 218 ? 145.416 150.401 124.161 1.00 248.37 ?  218  ALA B N   1 
ATOM   4390 C CA  . ALA B 1 218 ? 144.305 151.326 124.311 1.00 248.37 ?  218  ALA B CA  1 
ATOM   4391 C C   . ALA B 1 218 ? 143.140 150.748 125.104 1.00 248.37 ?  218  ALA B C   1 
ATOM   4392 O O   . ALA B 1 218 ? 142.458 151.480 125.813 1.00 248.37 ?  218  ALA B O   1 
ATOM   4393 C CB  . ALA B 1 218 ? 143.849 151.813 122.955 1.00 248.37 ?  218  ALA B CB  1 
ATOM   4394 N N   . LEU B 1 219 ? 142.907 149.446 125.006 1.00 254.00 ?  219  LEU B N   1 
ATOM   4395 C CA  . LEU B 1 219 ? 141.855 148.833 125.804 1.00 254.00 ?  219  LEU B CA  1 
ATOM   4396 C C   . LEU B 1 219 ? 142.261 148.785 127.264 1.00 254.00 ?  219  LEU B C   1 
ATOM   4397 O O   . LEU B 1 219 ? 141.441 149.028 128.134 1.00 254.00 ?  219  LEU B O   1 
ATOM   4398 C CB  . LEU B 1 219 ? 141.516 147.433 125.307 1.00 254.00 ?  219  LEU B CB  1 
ATOM   4399 C CG  . LEU B 1 219 ? 140.039 147.050 125.224 1.00 254.00 ?  219  LEU B CG  1 
ATOM   4400 C CD1 . LEU B 1 219 ? 139.789 145.722 125.914 1.00 254.00 ?  219  LEU B CD1 1 
ATOM   4401 C CD2 . LEU B 1 219 ? 139.127 148.128 125.786 1.00 254.00 ?  219  LEU B CD2 1 
ATOM   4402 N N   . THR B 1 220 ? 143.523 148.480 127.544 1.00 260.38 ?  220  THR B N   1 
ATOM   4403 C CA  . THR B 1 220 ? 143.995 148.484 128.920 1.00 260.38 ?  220  THR B CA  1 
ATOM   4404 C C   . THR B 1 220 ? 143.743 149.849 129.530 1.00 260.38 ?  220  THR B C   1 
ATOM   4405 O O   . THR B 1 220 ? 143.251 149.956 130.652 1.00 260.38 ?  220  THR B O   1 
ATOM   4406 C CB  . THR B 1 220 ? 145.497 148.174 129.008 1.00 260.38 ?  220  THR B CB  1 
ATOM   4407 O OG1 . THR B 1 220 ? 145.792 146.989 128.263 1.00 260.38 ?  220  THR B OG1 1 
ATOM   4408 C CG2 . THR B 1 220 ? 145.910 147.966 130.440 1.00 260.38 ?  220  THR B CG2 1 
ATOM   4409 N N   . ALA B 1 221 ? 144.064 150.901 128.787 1.00 244.81 ?  221  ALA B N   1 
ATOM   4410 C CA  . ALA B 1 221 ? 143.872 152.252 129.288 1.00 244.81 ?  221  ALA B CA  1 
ATOM   4411 C C   . ALA B 1 221 ? 142.401 152.566 129.487 1.00 244.81 ?  221  ALA B C   1 
ATOM   4412 O O   . ALA B 1 221 ? 142.027 153.186 130.475 1.00 244.81 ?  221  ALA B O   1 
ATOM   4413 C CB  . ALA B 1 221 ? 144.509 153.251 128.344 1.00 244.81 ?  221  ALA B CB  1 
ATOM   4414 N N   . GLY B 1 222 ? 141.559 152.131 128.560 1.00 244.62 ?  222  GLY B N   1 
ATOM   4415 C CA  . GLY B 1 222 ? 140.133 152.357 128.685 1.00 244.62 ?  222  GLY B CA  1 
ATOM   4416 C C   . GLY B 1 222 ? 139.505 151.595 129.830 1.00 244.62 ?  222  GLY B C   1 
ATOM   4417 O O   . GLY B 1 222 ? 138.525 152.047 130.412 1.00 244.62 ?  222  GLY B O   1 
ATOM   4418 N N   . LEU B 1 223 ? 140.062 150.438 130.162 1.00 242.33 ?  223  LEU B N   1 
ATOM   4419 C CA  . LEU B 1 223 ? 139.523 149.626 131.246 1.00 242.33 ?  223  LEU B CA  1 
ATOM   4420 C C   . LEU B 1 223 ? 140.047 150.076 132.597 1.00 242.33 ?  223  LEU B C   1 
ATOM   4421 O O   . LEU B 1 223 ? 139.493 149.712 133.628 1.00 242.33 ?  223  LEU B O   1 
ATOM   4422 C CB  . LEU B 1 223 ? 139.854 148.153 131.031 1.00 242.33 ?  223  LEU B CB  1 
ATOM   4423 C CG  . LEU B 1 223 ? 139.170 147.412 129.887 1.00 242.33 ?  223  LEU B CG  1 
ATOM   4424 C CD1 . LEU B 1 223 ? 139.868 146.080 129.678 1.00 242.33 ?  223  LEU B CD1 1 
ATOM   4425 C CD2 . LEU B 1 223 ? 137.690 147.215 130.170 1.00 242.33 ?  223  LEU B CD2 1 
ATOM   4426 N N   . GLY B 1 224 ? 141.111 150.865 132.599 1.00 257.32 ?  224  GLY B N   1 
ATOM   4427 C CA  . GLY B 1 224 ? 141.657 151.368 133.842 1.00 257.32 ?  224  GLY B CA  1 
ATOM   4428 C C   . GLY B 1 224 ? 141.245 152.797 134.096 1.00 257.32 ?  224  GLY B C   1 
ATOM   4429 O O   . GLY B 1 224 ? 141.787 153.457 134.976 1.00 257.32 ?  224  GLY B O   1 
ATOM   4430 N N   . SER B 1 225 ? 140.280 153.285 133.329 1.00 236.65 ?  225  SER B N   1 
ATOM   4431 C CA  . SER B 1 225 ? 139.818 154.654 133.491 1.00 236.65 ?  225  SER B CA  1 
ATOM   4432 C C   . SER B 1 225 ? 138.567 154.710 134.345 1.00 236.65 ?  225  SER B C   1 
ATOM   4433 O O   . SER B 1 225 ? 138.354 155.673 135.074 1.00 236.65 ?  225  SER B O   1 
ATOM   4434 C CB  . SER B 1 225 ? 139.543 155.275 132.128 1.00 236.65 ?  225  SER B CB  1 
ATOM   4435 O OG  . SER B 1 225 ? 138.508 154.585 131.458 1.00 236.65 ?  225  SER B OG  1 
ATOM   4436 N N   . GLY B 1 226 ? 137.734 153.679 134.262 1.00 225.32 ?  226  GLY B N   1 
ATOM   4437 C CA  . GLY B 1 226 ? 136.492 153.668 135.010 1.00 225.32 ?  226  GLY B CA  1 
ATOM   4438 C C   . GLY B 1 226 ? 135.344 154.119 134.141 1.00 225.32 ?  226  GLY B C   1 
ATOM   4439 O O   . GLY B 1 226 ? 134.186 154.016 134.536 1.00 225.32 ?  226  GLY B O   1 
ATOM   4440 N N   . ILE B 1 227 ? 135.657 154.626 132.955 1.00 196.92 ?  227  ILE B N   1 
ATOM   4441 C CA  . ILE B 1 227 ? 134.630 155.067 132.026 1.00 196.92 ?  227  ILE B CA  1 
ATOM   4442 C C   . ILE B 1 227 ? 133.972 153.804 131.513 1.00 196.92 ?  227  ILE B C   1 
ATOM   4443 O O   . ILE B 1 227 ? 134.666 152.836 131.218 1.00 196.92 ?  227  ILE B O   1 
ATOM   4444 C CB  . ILE B 1 227 ? 135.260 155.883 130.879 1.00 196.92 ?  227  ILE B CB  1 
ATOM   4445 C CG1 . ILE B 1 227 ? 135.964 157.116 131.443 1.00 196.92 ?  227  ILE B CG1 1 
ATOM   4446 C CG2 . ILE B 1 227 ? 134.223 156.312 129.855 1.00 196.92 ?  227  ILE B CG2 1 
ATOM   4447 C CD1 . ILE B 1 227 ? 135.058 158.019 132.250 1.00 196.92 ?  227  ILE B CD1 1 
ATOM   4448 N N   . PRO B 1 228 ? 132.606 153.773 131.432 1.00 174.25 ?  228  PRO B N   1 
ATOM   4449 C CA  . PRO B 1 228 ? 132.024 152.487 131.020 1.00 174.25 ?  228  PRO B CA  1 
ATOM   4450 C C   . PRO B 1 228 ? 132.283 152.079 129.580 1.00 174.25 ?  228  PRO B C   1 
ATOM   4451 O O   . PRO B 1 228 ? 131.421 152.265 128.726 1.00 174.25 ?  228  PRO B O   1 
ATOM   4452 C CB  . PRO B 1 228 ? 130.525 152.688 131.253 1.00 174.25 ?  228  PRO B CB  1 
ATOM   4453 C CG  . PRO B 1 228 ? 130.315 154.153 131.154 1.00 174.25 ?  228  PRO B CG  1 
ATOM   4454 C CD  . PRO B 1 228 ? 131.536 154.743 131.778 1.00 174.25 ?  228  PRO B CD  1 
ATOM   4455 N N   . VAL B 1 229 ? 133.453 151.519 129.308 1.00 202.83 ?  229  VAL B N   1 
ATOM   4456 C CA  . VAL B 1 229 ? 133.749 151.023 127.974 1.00 202.83 ?  229  VAL B CA  1 
ATOM   4457 C C   . VAL B 1 229 ? 133.738 149.512 128.095 1.00 202.83 ?  229  VAL B C   1 
ATOM   4458 O O   . VAL B 1 229 ? 133.813 148.973 129.201 1.00 202.83 ?  229  VAL B O   1 
ATOM   4459 C CB  . VAL B 1 229 ? 135.107 151.534 127.459 1.00 202.83 ?  229  VAL B CB  1 
ATOM   4460 C CG1 . VAL B 1 229 ? 135.246 153.021 127.740 1.00 202.83 ?  229  VAL B CG1 1 
ATOM   4461 C CG2 . VAL B 1 229 ? 136.259 150.762 128.081 1.00 202.83 ?  229  VAL B CG2 1 
ATOM   4462 N N   . GLY B 1 230 ? 133.617 148.813 126.979 1.00 199.38 ?  230  GLY B N   1 
ATOM   4463 C CA  . GLY B 1 230 ? 133.525 147.372 127.045 1.00 199.38 ?  230  GLY B CA  1 
ATOM   4464 C C   . GLY B 1 230 ? 134.843 146.666 126.889 1.00 199.38 ?  230  GLY B C   1 
ATOM   4465 O O   . GLY B 1 230 ? 135.876 147.300 126.700 1.00 199.38 ?  230  GLY B O   1 
ATOM   4466 N N   . LYS B 1 231 ? 134.811 145.345 126.960 1.00 223.11 ?  231  LYS B N   1 
ATOM   4467 C CA  . LYS B 1 231 ? 136.026 144.565 126.836 1.00 223.11 ?  231  LYS B CA  1 
ATOM   4468 C C   . LYS B 1 231 ? 135.767 143.439 125.858 1.00 223.11 ?  231  LYS B C   1 
ATOM   4469 O O   . LYS B 1 231 ? 136.631 143.109 125.057 1.00 223.11 ?  231  LYS B O   1 
ATOM   4470 C CB  . LYS B 1 231 ? 136.409 144.007 128.206 1.00 223.11 ?  231  LYS B CB  1 
ATOM   4471 C CG  . LYS B 1 231 ? 137.725 143.254 128.246 1.00 223.11 ?  231  LYS B CG  1 
ATOM   4472 C CD  . LYS B 1 231 ? 137.949 142.620 129.608 1.00 223.11 ?  231  LYS B CD  1 
ATOM   4473 C CE  . LYS B 1 231 ? 136.807 142.934 130.559 1.00 223.11 ?  231  LYS B CE  1 
ATOM   4474 N NZ  . LYS B 1 231 ? 136.469 141.766 131.419 1.00 223.11 1  231  LYS B NZ  1 
ATOM   4475 N N   . GLU B 1 232 ? 134.567 142.868 125.898 1.00 245.05 ?  232  GLU B N   1 
ATOM   4476 C CA  . GLU B 1 232 ? 134.227 141.737 125.030 1.00 245.05 ?  232  GLU B CA  1 
ATOM   4477 C C   . GLU B 1 232 ? 134.496 141.968 123.552 1.00 245.05 ?  232  GLU B C   1 
ATOM   4478 O O   . GLU B 1 232 ? 135.135 141.142 122.901 1.00 245.05 ?  232  GLU B O   1 
ATOM   4479 C CB  . GLU B 1 232 ? 132.768 141.334 125.248 1.00 245.05 ?  232  GLU B CB  1 
ATOM   4480 C CG  . GLU B 1 232 ? 132.061 140.753 124.040 1.00 245.05 ?  232  GLU B CG  1 
ATOM   4481 C CD  . GLU B 1 232 ? 130.894 141.606 123.604 1.00 245.05 ?  232  GLU B CD  1 
ATOM   4482 O OE1 . GLU B 1 232 ? 131.099 142.557 122.823 1.00 245.05 ?  232  GLU B OE1 1 
ATOM   4483 O OE2 . GLU B 1 232 ? 129.766 141.327 124.049 1.00 245.05 -1 232  GLU B OE2 1 
ATOM   4484 N N   . GLY B 1 233 ? 134.011 143.081 123.017 1.00 234.26 ?  233  GLY B N   1 
ATOM   4485 C CA  . GLY B 1 233 ? 134.202 143.353 121.609 1.00 234.26 ?  233  GLY B CA  1 
ATOM   4486 C C   . GLY B 1 233 ? 135.646 143.442 121.180 1.00 234.26 ?  233  GLY B C   1 
ATOM   4487 O O   . GLY B 1 233 ? 136.079 142.687 120.315 1.00 234.26 ?  233  GLY B O   1 
ATOM   4488 N N   . PRO B 1 234 ? 136.400 144.381 121.767 1.00 242.17 ?  234  PRO B N   1 
ATOM   4489 C CA  . PRO B 1 234 ? 137.822 144.468 121.443 1.00 242.17 ?  234  PRO B CA  1 
ATOM   4490 C C   . PRO B 1 234 ? 138.551 143.149 121.625 1.00 242.17 ?  234  PRO B C   1 
ATOM   4491 O O   . PRO B 1 234 ? 139.425 142.840 120.831 1.00 242.17 ?  234  PRO B O   1 
ATOM   4492 C CB  . PRO B 1 234 ? 138.330 145.482 122.455 1.00 242.17 ?  234  PRO B CB  1 
ATOM   4493 C CG  . PRO B 1 234 ? 137.173 146.390 122.666 1.00 242.17 ?  234  PRO B CG  1 
ATOM   4494 C CD  . PRO B 1 234 ? 135.958 145.516 122.596 1.00 242.17 ?  234  PRO B CD  1 
ATOM   4495 N N   . PHE B 1 235 ? 138.198 142.386 122.649 1.00 250.74 ?  235  PHE B N   1 
ATOM   4496 C CA  . PHE B 1 235 ? 138.852 141.112 122.921 1.00 250.74 ?  235  PHE B CA  1 
ATOM   4497 C C   . PHE B 1 235 ? 138.656 140.115 121.796 1.00 250.74 ?  235  PHE B C   1 
ATOM   4498 O O   . PHE B 1 235 ? 139.576 139.388 121.458 1.00 250.74 ?  235  PHE B O   1 
ATOM   4499 C CB  . PHE B 1 235 ? 138.358 140.520 124.236 1.00 250.74 ?  235  PHE B CB  1 
ATOM   4500 C CG  . PHE B 1 235 ? 139.271 140.784 125.393 1.00 250.74 ?  235  PHE B CG  1 
ATOM   4501 C CD1 . PHE B 1 235 ? 140.009 141.949 125.456 1.00 250.74 ?  235  PHE B CD1 1 
ATOM   4502 C CD2 . PHE B 1 235 ? 139.398 139.865 126.413 1.00 250.74 ?  235  PHE B CD2 1 
ATOM   4503 C CE1 . PHE B 1 235 ? 140.851 142.195 126.520 1.00 250.74 ?  235  PHE B CE1 1 
ATOM   4504 C CE2 . PHE B 1 235 ? 140.235 140.105 127.482 1.00 250.74 ?  235  PHE B CE2 1 
ATOM   4505 C CZ  . PHE B 1 235 ? 140.967 141.271 127.536 1.00 250.74 ?  235  PHE B CZ  1 
ATOM   4506 N N   . VAL B 1 236 ? 137.463 140.069 121.216 1.00 259.83 ?  236  VAL B N   1 
ATOM   4507 C CA  . VAL B 1 236 ? 137.216 139.187 120.080 1.00 259.83 ?  236  VAL B CA  1 
ATOM   4508 C C   . VAL B 1 236 ? 138.145 139.570 118.938 1.00 259.83 ?  236  VAL B C   1 
ATOM   4509 O O   . VAL B 1 236 ? 138.732 138.701 118.301 1.00 259.83 ?  236  VAL B O   1 
ATOM   4510 C CB  . VAL B 1 236 ? 135.736 139.233 119.654 1.00 259.83 ?  236  VAL B CB  1 
ATOM   4511 C CG1 . VAL B 1 236 ? 135.568 139.006 118.161 1.00 259.83 ?  236  VAL B CG1 1 
ATOM   4512 C CG2 . VAL B 1 236 ? 134.932 138.217 120.445 1.00 259.83 ?  236  VAL B CG2 1 
ATOM   4513 N N   . HIS B 1 237 ? 138.317 140.868 118.700 1.00 254.65 ?  237  HIS B N   1 
ATOM   4514 C CA  . HIS B 1 237 ? 139.240 141.321 117.663 1.00 254.65 ?  237  HIS B CA  1 
ATOM   4515 C C   . HIS B 1 237 ? 140.675 140.980 118.037 1.00 254.65 ?  237  HIS B C   1 
ATOM   4516 O O   . HIS B 1 237 ? 141.409 140.444 117.219 1.00 254.65 ?  237  HIS B O   1 
ATOM   4517 C CB  . HIS B 1 237 ? 139.090 142.826 117.425 1.00 254.65 ?  237  HIS B CB  1 
ATOM   4518 C CG  . HIS B 1 237 ? 139.959 143.359 116.328 1.00 254.65 ?  237  HIS B CG  1 
ATOM   4519 N ND1 . HIS B 1 237 ? 140.368 144.674 116.278 1.00 254.65 ?  237  HIS B ND1 1 
ATOM   4520 C CD2 . HIS B 1 237 ? 140.492 142.760 115.237 1.00 254.65 ?  237  HIS B CD2 1 
ATOM   4521 C CE1 . HIS B 1 237 ? 141.122 144.860 115.210 1.00 254.65 ?  237  HIS B CE1 1 
ATOM   4522 N NE2 . HIS B 1 237 ? 141.213 143.714 114.561 1.00 254.65 ?  237  HIS B NE2 1 
ATOM   4523 N N   . ILE B 1 238 ? 141.076 141.276 119.268 1.00 265.51 ?  238  ILE B N   1 
ATOM   4524 C CA  . ILE B 1 238 ? 142.426 140.962 119.734 1.00 265.51 ?  238  ILE B CA  1 
ATOM   4525 C C   . ILE B 1 238 ? 142.704 139.483 119.537 1.00 265.51 ?  238  ILE B C   1 
ATOM   4526 O O   . ILE B 1 238 ? 143.772 139.104 119.058 1.00 265.51 ?  238  ILE B O   1 
ATOM   4527 C CB  . ILE B 1 238 ? 142.595 141.344 121.222 1.00 265.51 ?  238  ILE B CB  1 
ATOM   4528 C CG1 . ILE B 1 238 ? 142.866 142.841 121.364 1.00 265.51 ?  238  ILE B CG1 1 
ATOM   4529 C CG2 . ILE B 1 238 ? 143.698 140.544 121.894 1.00 265.51 ?  238  ILE B CG2 1 
ATOM   4530 C CD1 . ILE B 1 238 ? 142.430 143.409 122.697 1.00 265.51 ?  238  ILE B CD1 1 
ATOM   4531 N N   . ALA B 1 239 ? 141.732 138.644 119.866 1.00 245.47 ?  239  ALA B N   1 
ATOM   4532 C CA  . ALA B 1 239 ? 141.915 137.207 119.743 1.00 245.47 ?  239  ALA B CA  1 
ATOM   4533 C C   . ALA B 1 239 ? 141.948 136.739 118.307 1.00 245.47 ?  239  ALA B C   1 
ATOM   4534 O O   . ALA B 1 239 ? 142.650 135.792 117.986 1.00 245.47 ?  239  ALA B O   1 
ATOM   4535 C CB  . ALA B 1 239 ? 140.832 136.480 120.500 1.00 245.47 ?  239  ALA B CB  1 
ATOM   4536 N N   . SER B 1 240 ? 141.186 137.391 117.440 1.00 275.90 ?  240  SER B N   1 
ATOM   4537 C CA  . SER B 1 240 ? 141.193 137.035 116.033 1.00 275.90 ?  240  SER B CA  1 
ATOM   4538 C C   . SER B 1 240 ? 142.499 137.463 115.395 1.00 275.90 ?  240  SER B C   1 
ATOM   4539 O O   . SER B 1 240 ? 142.993 136.789 114.498 1.00 275.90 ?  240  SER B O   1 
ATOM   4540 C CB  . SER B 1 240 ? 140.008 137.667 115.316 1.00 275.90 ?  240  SER B CB  1 
ATOM   4541 O OG  . SER B 1 240 ? 138.791 137.088 115.750 1.00 275.90 ?  240  SER B OG  1 
ATOM   4542 N N   . ILE B 1 241 ? 143.070 138.574 115.848 1.00 272.13 ?  241  ILE B N   1 
ATOM   4543 C CA  . ILE B 1 241 ? 144.371 138.983 115.339 1.00 272.13 ?  241  ILE B CA  1 
ATOM   4544 C C   . ILE B 1 241 ? 145.355 137.919 115.760 1.00 272.13 ?  241  ILE B C   1 
ATOM   4545 O O   . ILE B 1 241 ? 146.123 137.421 114.947 1.00 272.13 ?  241  ILE B O   1 
ATOM   4546 C CB  . ILE B 1 241 ? 144.843 140.326 115.921 1.00 272.13 ?  241  ILE B CB  1 
ATOM   4547 C CG1 . ILE B 1 241 ? 143.961 141.474 115.446 1.00 272.13 ?  241  ILE B CG1 1 
ATOM   4548 C CG2 . ILE B 1 241 ? 146.280 140.604 115.518 1.00 272.13 ?  241  ILE B CG2 1 
ATOM   4549 C CD1 . ILE B 1 241 ? 144.019 142.680 116.353 1.00 272.13 ?  241  ILE B CD1 1 
ATOM   4550 N N   . CYS B 1 242 ? 145.314 137.545 117.031 1.00 298.43 ?  242  CYS B N   1 
ATOM   4551 C CA  . CYS B 1 242 ? 146.226 136.535 117.538 1.00 298.43 ?  242  CYS B CA  1 
ATOM   4552 C C   . CYS B 1 242 ? 146.039 135.205 116.835 1.00 298.43 ?  242  CYS B C   1 
ATOM   4553 O O   . CYS B 1 242 ? 147.005 134.495 116.604 1.00 298.43 ?  242  CYS B O   1 
ATOM   4554 C CB  . CYS B 1 242 ? 146.041 136.360 119.038 1.00 298.43 ?  242  CYS B CB  1 
ATOM   4555 S SG  . CYS B 1 242 ? 147.549 136.545 120.010 1.00 298.43 ?  242  CYS B SG  1 
ATOM   4556 N N   . ALA B 1 243 ? 144.803 134.863 116.491 1.00 278.91 ?  243  ALA B N   1 
ATOM   4557 C CA  . ALA B 1 243 ? 144.542 133.624 115.773 1.00 278.91 ?  243  ALA B CA  1 
ATOM   4558 C C   . ALA B 1 243 ? 145.194 133.673 114.413 1.00 278.91 ?  243  ALA B C   1 
ATOM   4559 O O   . ALA B 1 243 ? 145.885 132.742 114.024 1.00 278.91 ?  243  ALA B O   1 
ATOM   4560 C CB  . ALA B 1 243 ? 143.052 133.393 115.635 1.00 278.91 ?  243  ALA B CB  1 
ATOM   4561 N N   . ALA B 1 244 ? 144.983 134.764 113.688 1.00 296.98 ?  244  ALA B N   1 
ATOM   4562 C CA  . ALA B 1 244 ? 145.597 134.919 112.378 1.00 296.98 ?  244  ALA B CA  1 
ATOM   4563 C C   . ALA B 1 244 ? 147.111 134.882 112.482 1.00 296.98 ?  244  ALA B C   1 
ATOM   4564 O O   . ALA B 1 244 ? 147.774 134.226 111.684 1.00 296.98 ?  244  ALA B O   1 
ATOM   4565 C CB  . ALA B 1 244 ? 145.147 136.217 111.739 1.00 296.98 ?  244  ALA B CB  1 
ATOM   4566 N N   . VAL B 1 245 ? 147.663 135.582 113.466 1.00 291.00 ?  245  VAL B N   1 
ATOM   4567 C CA  . VAL B 1 245 ? 149.107 135.608 113.645 1.00 291.00 ?  245  VAL B CA  1 
ATOM   4568 C C   . VAL B 1 245 ? 149.624 134.215 113.961 1.00 291.00 ?  245  VAL B C   1 
ATOM   4569 O O   . VAL B 1 245 ? 150.586 133.761 113.354 1.00 291.00 ?  245  VAL B O   1 
ATOM   4570 C CB  . VAL B 1 245 ? 149.521 136.603 114.745 1.00 291.00 ?  245  VAL B CB  1 
ATOM   4571 C CG1 . VAL B 1 245 ? 150.961 136.378 115.180 1.00 291.00 ?  245  VAL B CG1 1 
ATOM   4572 C CG2 . VAL B 1 245 ? 149.337 138.031 114.256 1.00 291.00 ?  245  VAL B CG2 1 
ATOM   4573 N N   . LEU B 1 246 ? 148.973 133.524 114.890 1.00 301.56 ?  246  LEU B N   1 
ATOM   4574 C CA  . LEU B 1 246 ? 149.400 132.181 115.258 1.00 301.56 ?  246  LEU B CA  1 
ATOM   4575 C C   . LEU B 1 246 ? 149.309 131.248 114.069 1.00 301.56 ?  246  LEU B C   1 
ATOM   4576 O O   . LEU B 1 246 ? 150.167 130.395 113.888 1.00 301.56 ?  246  LEU B O   1 
ATOM   4577 C CB  . LEU B 1 246 ? 148.566 131.636 116.414 1.00 301.56 ?  246  LEU B CB  1 
ATOM   4578 C CG  . LEU B 1 246 ? 149.315 131.382 117.720 1.00 301.56 ?  246  LEU B CG  1 
ATOM   4579 C CD1 . LEU B 1 246 ? 150.713 131.972 117.661 1.00 301.56 ?  246  LEU B CD1 1 
ATOM   4580 C CD2 . LEU B 1 246 ? 148.542 131.969 118.887 1.00 301.56 ?  246  LEU B CD2 1 
ATOM   4581 N N   . SER B 1 247 ? 148.276 131.409 113.252 1.00 308.97 ?  247  SER B N   1 
ATOM   4582 C CA  . SER B 1 247 ? 148.126 130.577 112.068 1.00 308.97 ?  247  SER B CA  1 
ATOM   4583 C C   . SER B 1 247 ? 149.297 130.785 111.124 1.00 308.97 ?  247  SER B C   1 
ATOM   4584 O O   . SER B 1 247 ? 149.832 129.828 110.583 1.00 308.97 ?  247  SER B O   1 
ATOM   4585 C CB  . SER B 1 247 ? 146.809 130.877 111.358 1.00 308.97 ?  247  SER B CB  1 
ATOM   4586 O OG  . SER B 1 247 ? 147.032 131.364 110.047 1.00 308.97 ?  247  SER B OG  1 
ATOM   4587 N N   . LYS B 1 248 ? 149.708 132.032 110.934 1.00 305.64 ?  248  LYS B N   1 
ATOM   4588 C CA  . LYS B 1 248 ? 150.855 132.312 110.082 1.00 305.64 ?  248  LYS B CA  1 
ATOM   4589 C C   . LYS B 1 248 ? 152.122 131.762 110.709 1.00 305.64 ?  248  LYS B C   1 
ATOM   4590 O O   . LYS B 1 248 ? 152.905 131.088 110.047 1.00 305.64 ?  248  LYS B O   1 
ATOM   4591 C CB  . LYS B 1 248 ? 150.996 133.813 109.852 1.00 305.64 ?  248  LYS B CB  1 
ATOM   4592 C CG  . LYS B 1 248 ? 149.996 134.382 108.863 1.00 305.64 ?  248  LYS B CG  1 
ATOM   4593 C CD  . LYS B 1 248 ? 150.562 135.603 108.158 1.00 305.64 ?  248  LYS B CD  1 
ATOM   4594 C CE  . LYS B 1 248 ? 151.511 135.203 107.040 1.00 305.64 ?  248  LYS B CE  1 
ATOM   4595 N NZ  . LYS B 1 248 ? 152.916 135.606 107.326 1.00 305.64 1  248  LYS B NZ  1 
ATOM   4596 N N   . PHE B 1 249 ? 152.320 132.031 111.992 1.00 306.46 ?  249  PHE B N   1 
ATOM   4597 C CA  . PHE B 1 249 ? 153.504 131.546 112.687 1.00 306.46 ?  249  PHE B CA  1 
ATOM   4598 C C   . PHE B 1 249 ? 153.612 130.031 112.594 1.00 306.46 ?  249  PHE B C   1 
ATOM   4599 O O   . PHE B 1 249 ? 154.704 129.491 112.451 1.00 306.46 ?  249  PHE B O   1 
ATOM   4600 C CB  . PHE B 1 249 ? 153.483 132.013 114.148 1.00 306.46 ?  249  PHE B CB  1 
ATOM   4601 C CG  . PHE B 1 249 ? 154.162 131.073 115.107 1.00 306.46 ?  249  PHE B CG  1 
ATOM   4602 C CD1 . PHE B 1 249 ? 155.543 131.061 115.229 1.00 306.46 ?  249  PHE B CD1 1 
ATOM   4603 C CD2 . PHE B 1 249 ? 153.418 130.214 115.901 1.00 306.46 ?  249  PHE B CD2 1 
ATOM   4604 C CE1 . PHE B 1 249 ? 156.167 130.198 116.109 1.00 306.46 ?  249  PHE B CE1 1 
ATOM   4605 C CE2 . PHE B 1 249 ? 154.036 129.350 116.784 1.00 306.46 ?  249  PHE B CE2 1 
ATOM   4606 C CZ  . PHE B 1 249 ? 155.413 129.343 116.889 1.00 306.46 ?  249  PHE B CZ  1 
ATOM   4607 N N   . MET B 1 250 ? 152.485 129.338 112.670 1.00 308.01 ?  250  MET B N   1 
ATOM   4608 C CA  . MET B 1 250 ? 152.524 127.885 112.658 1.00 308.01 ?  250  MET B CA  1 
ATOM   4609 C C   . MET B 1 250 ? 152.540 127.317 111.254 1.00 308.01 ?  250  MET B C   1 
ATOM   4610 O O   . MET B 1 250 ? 153.504 126.667 110.859 1.00 308.01 ?  250  MET B O   1 
ATOM   4611 C CB  . MET B 1 250 ? 151.343 127.314 113.437 1.00 308.01 ?  250  MET B CB  1 
ATOM   4612 C CG  . MET B 1 250 ? 151.728 126.219 114.411 1.00 308.01 ?  250  MET B CG  1 
ATOM   4613 S SD  . MET B 1 250 ? 150.533 126.065 115.745 1.00 308.01 ?  250  MET B SD  1 
ATOM   4614 C CE  . MET B 1 250 ? 150.478 127.751 116.340 1.00 308.01 ?  250  MET B CE  1 
ATOM   4615 N N   . SER B 1 251 ? 151.479 127.554 110.497 1.00 303.41 ?  251  SER B N   1 
ATOM   4616 C CA  . SER B 1 251 ? 151.381 126.977 109.160 1.00 303.41 ?  251  SER B CA  1 
ATOM   4617 C C   . SER B 1 251 ? 152.422 127.495 108.186 1.00 303.41 ?  251  SER B C   1 
ATOM   4618 O O   . SER B 1 251 ? 153.225 126.720 107.669 1.00 303.41 ?  251  SER B O   1 
ATOM   4619 C CB  . SER B 1 251 ? 149.977 127.184 108.584 1.00 303.41 ?  251  SER B CB  1 
ATOM   4620 O OG  . SER B 1 251 ? 149.987 127.095 107.171 1.00 303.41 ?  251  SER B OG  1 
ATOM   4621 N N   . VAL B 1 252 ? 152.422 128.795 107.925 1.00 294.29 ?  252  VAL B N   1 
ATOM   4622 C CA  . VAL B 1 252 ? 153.341 129.327 106.920 1.00 294.29 ?  252  VAL B CA  1 
ATOM   4623 C C   . VAL B 1 252 ? 154.802 129.342 107.376 1.00 294.29 ?  252  VAL B C   1 
ATOM   4624 O O   . VAL B 1 252 ? 155.711 129.394 106.545 1.00 294.29 ?  252  VAL B O   1 
ATOM   4625 C CB  . VAL B 1 252 ? 152.865 130.692 106.362 1.00 294.29 ?  252  VAL B CB  1 
ATOM   4626 C CG1 . VAL B 1 252 ? 151.368 130.857 106.571 1.00 294.29 ?  252  VAL B CG1 1 
ATOM   4627 C CG2 . VAL B 1 252 ? 153.631 131.855 106.967 1.00 294.29 ?  252  VAL B CG2 1 
ATOM   4628 N N   . PHE B 1 253 ? 155.038 129.265 108.683 1.00 291.46 ?  253  PHE B N   1 
ATOM   4629 C CA  . PHE B 1 253 ? 156.410 129.203 109.178 1.00 291.46 ?  253  PHE B CA  1 
ATOM   4630 C C   . PHE B 1 253 ? 156.662 127.883 109.896 1.00 291.46 ?  253  PHE B C   1 
ATOM   4631 O O   . PHE B 1 253 ? 157.036 127.865 111.067 1.00 291.46 ?  253  PHE B O   1 
ATOM   4632 C CB  . PHE B 1 253 ? 156.715 130.376 110.111 1.00 291.46 ?  253  PHE B CB  1 
ATOM   4633 C CG  . PHE B 1 253 ? 156.598 131.723 109.457 1.00 291.46 ?  253  PHE B CG  1 
ATOM   4634 C CD1 . PHE B 1 253 ? 157.272 131.998 108.279 1.00 291.46 ?  253  PHE B CD1 1 
ATOM   4635 C CD2 . PHE B 1 253 ? 155.821 132.718 110.025 1.00 291.46 ?  253  PHE B CD2 1 
ATOM   4636 C CE1 . PHE B 1 253 ? 157.165 133.237 107.676 1.00 291.46 ?  253  PHE B CE1 1 
ATOM   4637 C CE2 . PHE B 1 253 ? 155.709 133.958 109.429 1.00 291.46 ?  253  PHE B CE2 1 
ATOM   4638 C CZ  . PHE B 1 253 ? 156.384 134.219 108.252 1.00 291.46 ?  253  PHE B CZ  1 
ATOM   4639 N N   . TYR B 1 262 ? 139.583 126.285 107.251 1.00 316.42 ?  262  TYR B N   1 
ATOM   4640 C CA  . TYR B 1 262 ? 140.010 127.427 106.453 1.00 316.42 ?  262  TYR B CA  1 
ATOM   4641 C C   . TYR B 1 262 ? 140.227 128.651 107.329 1.00 316.42 ?  262  TYR B C   1 
ATOM   4642 O O   . TYR B 1 262 ? 140.299 128.535 108.549 1.00 316.42 ?  262  TYR B O   1 
ATOM   4643 C CB  . TYR B 1 262 ? 138.995 127.733 105.346 1.00 316.42 ?  262  TYR B CB  1 
ATOM   4644 C CG  . TYR B 1 262 ? 137.600 127.207 105.608 1.00 316.42 ?  262  TYR B CG  1 
ATOM   4645 C CD1 . TYR B 1 262 ? 136.693 127.939 106.359 1.00 316.42 ?  262  TYR B CD1 1 
ATOM   4646 C CD2 . TYR B 1 262 ? 137.187 125.985 105.092 1.00 316.42 ?  262  TYR B CD2 1 
ATOM   4647 C CE1 . TYR B 1 262 ? 135.417 127.467 106.597 1.00 316.42 ?  262  TYR B CE1 1 
ATOM   4648 C CE2 . TYR B 1 262 ? 135.914 125.504 105.329 1.00 316.42 ?  262  TYR B CE2 1 
ATOM   4649 C CZ  . TYR B 1 262 ? 135.034 126.250 106.082 1.00 316.42 ?  262  TYR B CZ  1 
ATOM   4650 O OH  . TYR B 1 262 ? 133.763 125.778 106.319 1.00 316.42 ?  262  TYR B OH  1 
ATOM   4651 N N   . TYR B 1 263 ? 140.329 129.822 106.712 1.00 309.96 ?  263  TYR B N   1 
ATOM   4652 C CA  . TYR B 1 263 ? 140.550 131.049 107.467 1.00 309.96 ?  263  TYR B CA  1 
ATOM   4653 C C   . TYR B 1 263 ? 139.403 131.314 108.425 1.00 309.96 ?  263  TYR B C   1 
ATOM   4654 O O   . TYR B 1 263 ? 139.617 131.785 109.538 1.00 309.96 ?  263  TYR B O   1 
ATOM   4655 C CB  . TYR B 1 263 ? 140.718 132.231 106.515 1.00 309.96 ?  263  TYR B CB  1 
ATOM   4656 C CG  . TYR B 1 263 ? 141.465 133.406 107.102 1.00 309.96 ?  263  TYR B CG  1 
ATOM   4657 C CD1 . TYR B 1 263 ? 142.457 133.221 108.056 1.00 309.96 ?  263  TYR B CD1 1 
ATOM   4658 C CD2 . TYR B 1 263 ? 141.180 134.702 106.695 1.00 309.96 ?  263  TYR B CD2 1 
ATOM   4659 C CE1 . TYR B 1 263 ? 143.141 134.296 108.592 1.00 309.96 ?  263  TYR B CE1 1 
ATOM   4660 C CE2 . TYR B 1 263 ? 141.860 135.782 107.224 1.00 309.96 ?  263  TYR B CE2 1 
ATOM   4661 C CZ  . TYR B 1 263 ? 142.838 135.574 108.171 1.00 309.96 ?  263  TYR B CZ  1 
ATOM   4662 O OH  . TYR B 1 263 ? 143.513 136.650 108.695 1.00 309.96 ?  263  TYR B OH  1 
ATOM   4663 N N   . SER B 1 264 ? 138.185 131.004 108.001 1.00 293.58 ?  264  SER B N   1 
ATOM   4664 C CA  . SER B 1 264 ? 137.023 131.233 108.847 1.00 293.58 ?  264  SER B CA  1 
ATOM   4665 C C   . SER B 1 264 ? 137.069 130.362 110.086 1.00 293.58 ?  264  SER B C   1 
ATOM   4666 O O   . SER B 1 264 ? 136.645 130.786 111.151 1.00 293.58 ?  264  SER B O   1 
ATOM   4667 C CB  . SER B 1 264 ? 135.728 130.981 108.077 1.00 293.58 ?  264  SER B CB  1 
ATOM   4668 O OG  . SER B 1 264 ? 134.821 130.213 108.847 1.00 293.58 ?  264  SER B OG  1 
ATOM   4669 N N   . ASP B 1 265 ? 137.588 129.148 109.954 1.00 302.56 ?  265  ASP B N   1 
ATOM   4670 C CA  . ASP B 1 265 ? 137.708 128.260 111.101 1.00 302.56 ?  265  ASP B CA  1 
ATOM   4671 C C   . ASP B 1 265 ? 138.682 128.835 112.108 1.00 302.56 ?  265  ASP B C   1 
ATOM   4672 O O   . ASP B 1 265 ? 138.394 128.873 113.302 1.00 302.56 ?  265  ASP B O   1 
ATOM   4673 C CB  . ASP B 1 265 ? 138.167 126.878 110.651 1.00 302.56 ?  265  ASP B CB  1 
ATOM   4674 C CG  . ASP B 1 265 ? 137.142 126.183 109.783 1.00 302.56 ?  265  ASP B CG  1 
ATOM   4675 O OD1 . ASP B 1 265 ? 135.992 126.664 109.729 1.00 302.56 ?  265  ASP B OD1 1 
ATOM   4676 O OD2 . ASP B 1 265 ? 137.482 125.160 109.155 1.00 302.56 -1 265  ASP B OD2 1 
ATOM   4677 N N   . ILE B 1 266 ? 139.833 129.290 111.634 1.00 288.36 ?  266  ILE B N   1 
ATOM   4678 C CA  . ILE B 1 266 ? 140.818 129.903 112.513 1.00 288.36 ?  266  ILE B CA  1 
ATOM   4679 C C   . ILE B 1 266 ? 140.206 131.089 113.242 1.00 288.36 ?  266  ILE B C   1 
ATOM   4680 O O   . ILE B 1 266 ? 140.308 131.195 114.465 1.00 288.36 ?  266  ILE B O   1 
ATOM   4681 C CB  . ILE B 1 266 ? 142.051 130.349 111.700 1.00 288.36 ?  266  ILE B CB  1 
ATOM   4682 C CG1 . ILE B 1 266 ? 142.929 129.143 111.371 1.00 288.36 ?  266  ILE B CG1 1 
ATOM   4683 C CG2 . ILE B 1 266 ? 142.857 131.409 112.431 1.00 288.36 ?  266  ILE B CG2 1 
ATOM   4684 C CD1 . ILE B 1 266 ? 143.471 129.154 109.960 1.00 288.36 ?  266  ILE B CD1 1 
ATOM   4685 N N   . LEU B 1 267 ? 139.593 132.003 112.498 1.00 268.67 ?  267  LEU B N   1 
ATOM   4686 C CA  . LEU B 1 267 ? 139.056 133.222 113.104 1.00 268.67 ?  267  LEU B CA  1 
ATOM   4687 C C   . LEU B 1 267 ? 137.926 132.943 114.064 1.00 268.67 ?  267  LEU B C   1 
ATOM   4688 O O   . LEU B 1 267 ? 137.754 133.654 115.050 1.00 268.67 ?  267  LEU B O   1 
ATOM   4689 C CB  . LEU B 1 267 ? 138.573 134.179 112.019 1.00 268.67 ?  267  LEU B CB  1 
ATOM   4690 C CG  . LEU B 1 267 ? 139.512 135.292 111.558 1.00 268.67 ?  267  LEU B CG  1 
ATOM   4691 C CD1 . LEU B 1 267 ? 140.950 135.035 111.981 1.00 268.67 ?  267  LEU B CD1 1 
ATOM   4692 C CD2 . LEU B 1 267 ? 139.410 135.442 110.051 1.00 268.67 ?  267  LEU B CD2 1 
ATOM   4693 N N   . THR B 1 268 ? 137.150 131.910 113.779 1.00 265.95 ?  268  THR B N   1 
ATOM   4694 C CA  . THR B 1 268 ? 136.025 131.576 114.632 1.00 265.95 ?  268  THR B CA  1 
ATOM   4695 C C   . THR B 1 268 ? 136.516 131.128 116.002 1.00 265.95 ?  268  THR B C   1 
ATOM   4696 O O   . THR B 1 268 ? 135.960 131.531 117.028 1.00 265.95 ?  268  THR B O   1 
ATOM   4697 C CB  . THR B 1 268 ? 135.135 130.512 113.966 1.00 30.00  ?  268  THR B CB  1 
ATOM   4698 O OG1 . THR B 1 268 ? 133.907 131.113 113.537 1.00 30.00  ?  268  THR B OG1 1 
ATOM   4699 C CG2 . THR B 1 268 ? 134.833 129.392 114.914 1.00 30.00  ?  268  THR B CG2 1 
ATOM   4700 N N   . VAL B 1 269 ? 137.582 130.335 116.032 1.00 271.98 ?  269  VAL B N   1 
ATOM   4701 C CA  . VAL B 1 269 ? 138.143 129.900 117.302 1.00 271.98 ?  269  VAL B CA  1 
ATOM   4702 C C   . VAL B 1 269 ? 138.666 131.118 118.031 1.00 271.98 ?  269  VAL B C   1 
ATOM   4703 O O   . VAL B 1 269 ? 138.477 131.245 119.232 1.00 271.98 ?  269  VAL B O   1 
ATOM   4704 C CB  . VAL B 1 269 ? 139.253 128.858 117.102 1.00 271.98 ?  269  VAL B CB  1 
ATOM   4705 C CG1 . VAL B 1 269 ? 139.889 128.492 118.430 1.00 271.98 ?  269  VAL B CG1 1 
ATOM   4706 C CG2 . VAL B 1 269 ? 138.680 127.620 116.437 1.00 271.98 ?  269  VAL B CG2 1 
ATOM   4707 N N   . GLY B 1 270 ? 139.300 132.033 117.308 1.00 274.45 ?  270  GLY B N   1 
ATOM   4708 C CA  . GLY B 1 270 ? 139.759 133.262 117.924 1.00 274.45 ?  270  GLY B CA  1 
ATOM   4709 C C   . GLY B 1 270 ? 138.614 133.949 118.628 1.00 274.45 ?  270  GLY B C   1 
ATOM   4710 O O   . GLY B 1 270 ? 138.711 134.271 119.806 1.00 274.45 ?  270  GLY B O   1 
ATOM   4711 N N   . CYS B 1 271 ? 137.516 134.162 117.917 1.00 276.29 ?  271  CYS B N   1 
ATOM   4712 C CA  . CYS B 1 271 ? 136.352 134.786 118.522 1.00 276.29 ?  271  CYS B CA  1 
ATOM   4713 C C   . CYS B 1 271 ? 135.963 134.086 119.814 1.00 276.29 ?  271  CYS B C   1 
ATOM   4714 O O   . CYS B 1 271 ? 135.756 134.745 120.815 1.00 276.29 ?  271  CYS B O   1 
ATOM   4715 C CB  . CYS B 1 271 ? 135.178 134.786 117.548 1.00 276.29 ?  271  CYS B CB  1 
ATOM   4716 S SG  . CYS B 1 271 ? 135.434 135.777 116.060 1.00 276.29 ?  271  CYS B SG  1 
ATOM   4717 N N   . ALA B 1 272 ? 135.876 132.761 119.801 1.00 296.18 ?  272  ALA B N   1 
ATOM   4718 C CA  . ALA B 1 272 ? 135.489 131.990 120.983 1.00 296.18 ?  272  ALA B CA  1 
ATOM   4719 C C   . ALA B 1 272 ? 136.404 132.195 122.181 1.00 296.18 ?  272  ALA B C   1 
ATOM   4720 O O   . ALA B 1 272 ? 135.933 132.428 123.291 1.00 296.18 ?  272  ALA B O   1 
ATOM   4721 C CB  . ALA B 1 272 ? 135.406 130.517 120.640 1.00 296.18 ?  272  ALA B CB  1 
ATOM   4722 N N   . VAL B 1 273 ? 137.712 132.108 121.965 1.00 306.83 ?  273  VAL B N   1 
ATOM   4723 C CA  . VAL B 1 273 ? 138.658 132.269 123.062 1.00 306.83 ?  273  VAL B CA  1 
ATOM   4724 C C   . VAL B 1 273 ? 138.760 133.715 123.502 1.00 306.83 ?  273  VAL B C   1 
ATOM   4725 O O   . VAL B 1 273 ? 139.215 133.992 124.605 1.00 306.83 ?  273  VAL B O   1 
ATOM   4726 C CB  . VAL B 1 273 ? 140.050 131.702 122.720 1.00 306.83 ?  273  VAL B CB  1 
ATOM   4727 C CG1 . VAL B 1 273 ? 139.899 130.386 121.993 1.00 306.83 ?  273  VAL B CG1 1 
ATOM   4728 C CG2 . VAL B 1 273 ? 140.861 132.675 121.883 1.00 306.83 ?  273  VAL B CG2 1 
ATOM   4729 N N   . GLY B 1 274 ? 138.326 134.640 122.655 1.00 284.31 ?  274  GLY B N   1 
ATOM   4730 C CA  . GLY B 1 274 ? 138.337 136.038 123.024 1.00 284.31 ?  274  GLY B CA  1 
ATOM   4731 C C   . GLY B 1 274 ? 137.329 136.283 124.113 1.00 284.31 ?  274  GLY B C   1 
ATOM   4732 O O   . GLY B 1 274 ? 137.657 136.831 125.158 1.00 284.31 ?  274  GLY B O   1 
ATOM   4733 N N   . VAL B 1 275 ? 136.093 135.861 123.881 1.00 263.92 ?  275  VAL B N   1 
ATOM   4734 C CA  . VAL B 1 275 ? 135.048 136.082 124.868 1.00 263.92 ?  275  VAL B CA  1 
ATOM   4735 C C   . VAL B 1 275 ? 135.204 135.129 126.038 1.00 263.92 ?  275  VAL B C   1 
ATOM   4736 O O   . VAL B 1 275 ? 134.774 135.428 127.146 1.00 263.92 ?  275  VAL B O   1 
ATOM   4737 C CB  . VAL B 1 275 ? 133.646 135.961 124.257 1.00 263.92 ?  275  VAL B CB  1 
ATOM   4738 C CG1 . VAL B 1 275 ? 133.199 137.305 123.721 1.00 263.92 ?  275  VAL B CG1 1 
ATOM   4739 C CG2 . VAL B 1 275 ? 133.646 134.949 123.136 1.00 263.92 ?  275  VAL B CG2 1 
ATOM   4740 N N   . GLY B 1 276 ? 135.833 133.987 125.803 1.00 285.28 ?  276  GLY B N   1 
ATOM   4741 C CA  . GLY B 1 276 ? 136.069 133.045 126.877 1.00 285.28 ?  276  GLY B CA  1 
ATOM   4742 C C   . GLY B 1 276 ? 137.043 133.611 127.883 1.00 285.28 ?  276  GLY B C   1 
ATOM   4743 O O   . GLY B 1 276 ? 136.879 133.417 129.084 1.00 285.28 ?  276  GLY B O   1 
ATOM   4744 N N   . CYS B 1 277 ? 138.058 134.318 127.400 1.00 314.53 ?  277  CYS B N   1 
ATOM   4745 C CA  . CYS B 1 277 ? 139.051 134.907 128.289 1.00 314.53 ?  277  CYS B CA  1 
ATOM   4746 C C   . CYS B 1 277 ? 138.600 136.275 128.782 1.00 314.53 ?  277  CYS B C   1 
ATOM   4747 O O   . CYS B 1 277 ? 139.176 136.819 129.721 1.00 314.53 ?  277  CYS B O   1 
ATOM   4748 C CB  . CYS B 1 277 ? 140.415 134.981 127.597 1.00 314.53 ?  277  CYS B CB  1 
ATOM   4749 S SG  . CYS B 1 277 ? 140.643 136.397 126.505 1.00 314.53 ?  277  CYS B SG  1 
ATOM   4750 N N   . CYS B 1 278 ? 137.563 136.827 128.164 1.00 274.97 ?  278  CYS B N   1 
ATOM   4751 C CA  . CYS B 1 278 ? 137.027 138.109 128.604 1.00 274.97 ?  278  CYS B CA  1 
ATOM   4752 C C   . CYS B 1 278 ? 136.137 137.920 129.814 1.00 274.97 ?  278  CYS B C   1 
ATOM   4753 O O   . CYS B 1 278 ? 136.338 138.558 130.844 1.00 274.97 ?  278  CYS B O   1 
ATOM   4754 C CB  . CYS B 1 278 ? 136.221 138.762 127.485 1.00 274.97 ?  278  CYS B CB  1 
ATOM   4755 S SG  . CYS B 1 278 ? 135.324 140.240 127.988 1.00 274.97 ?  278  CYS B SG  1 
ATOM   4756 N N   . PHE B 1 279 ? 135.152 137.034 129.697 1.00 227.42 ?  279  PHE B N   1 
ATOM   4757 C CA  . PHE B 1 279 ? 134.222 136.804 130.794 1.00 227.42 ?  279  PHE B CA  1 
ATOM   4758 C C   . PHE B 1 279 ? 134.776 135.816 131.798 1.00 227.42 ?  279  PHE B C   1 
ATOM   4759 O O   . PHE B 1 279 ? 134.162 135.590 132.836 1.00 227.42 ?  279  PHE B O   1 
ATOM   4760 C CB  . PHE B 1 279 ? 132.894 136.244 130.286 1.00 227.42 ?  279  PHE B CB  1 
ATOM   4761 C CG  . PHE B 1 279 ? 132.347 136.938 129.077 1.00 227.42 ?  279  PHE B CG  1 
ATOM   4762 C CD1 . PHE B 1 279 ? 132.349 138.316 128.982 1.00 227.42 ?  279  PHE B CD1 1 
ATOM   4763 C CD2 . PHE B 1 279 ? 131.797 136.201 128.044 1.00 227.42 ?  279  PHE B CD2 1 
ATOM   4764 C CE1 . PHE B 1 279 ? 131.841 138.944 127.866 1.00 227.42 ?  279  PHE B CE1 1 
ATOM   4765 C CE2 . PHE B 1 279 ? 131.280 136.823 126.928 1.00 227.42 ?  279  PHE B CE2 1 
ATOM   4766 C CZ  . PHE B 1 279 ? 131.300 138.197 126.839 1.00 227.42 ?  279  PHE B CZ  1 
ATOM   4767 N N   . GLY B 1 280 ? 135.919 135.206 131.500 1.00 219.72 ?  280  GLY B N   1 
ATOM   4768 C CA  . GLY B 1 280 ? 136.453 134.183 132.381 1.00 219.72 ?  280  GLY B CA  1 
ATOM   4769 C C   . GLY B 1 280 ? 135.433 133.075 132.411 1.00 219.72 ?  280  GLY B C   1 
ATOM   4770 O O   . GLY B 1 280 ? 135.226 132.441 133.445 1.00 219.72 ?  280  GLY B O   1 
ATOM   4771 N N   . THR B 1 281 ? 134.782 132.839 131.280 1.00 234.03 ?  281  THR B N   1 
ATOM   4772 C CA  . THR B 1 281 ? 133.737 131.834 131.210 1.00 234.03 ?  281  THR B CA  1 
ATOM   4773 C C   . THR B 1 281 ? 133.976 131.044 129.941 1.00 234.03 ?  281  THR B C   1 
ATOM   4774 O O   . THR B 1 281 ? 133.696 131.528 128.846 1.00 234.03 ?  281  THR B O   1 
ATOM   4775 C CB  . THR B 1 281 ? 132.352 132.507 131.158 1.00 234.03 ?  281  THR B CB  1 
ATOM   4776 O OG1 . THR B 1 281 ? 132.098 133.182 132.397 1.00 234.03 ?  281  THR B OG1 1 
ATOM   4777 C CG2 . THR B 1 281 ? 131.266 131.494 130.926 1.00 234.03 ?  281  THR B CG2 1 
ATOM   4778 N N   . PRO B 1 282 ? 134.527 129.832 130.075 1.00 231.49 ?  282  PRO B N   1 
ATOM   4779 C CA  . PRO B 1 282 ? 134.850 129.030 128.891 1.00 231.49 ?  282  PRO B CA  1 
ATOM   4780 C C   . PRO B 1 282 ? 133.629 128.688 128.053 1.00 231.49 ?  282  PRO B C   1 
ATOM   4781 O O   . PRO B 1 282 ? 133.505 129.199 126.943 1.00 231.49 ?  282  PRO B O   1 
ATOM   4782 C CB  . PRO B 1 282 ? 135.444 127.752 129.484 1.00 231.49 ?  282  PRO B CB  1 
ATOM   4783 C CG  . PRO B 1 282 ? 135.895 128.129 130.853 1.00 231.49 ?  282  PRO B CG  1 
ATOM   4784 C CD  . PRO B 1 282 ? 134.927 129.168 131.325 1.00 231.49 ?  282  PRO B CD  1 
ATOM   4785 N N   . LEU B 1 283 ? 132.740 127.848 128.568 1.00 229.79 ?  283  LEU B N   1 
ATOM   4786 C CA  . LEU B 1 283 ? 131.582 127.408 127.792 1.00 229.79 ?  283  LEU B CA  1 
ATOM   4787 C C   . LEU B 1 283 ? 130.720 128.558 127.306 1.00 229.79 ?  283  LEU B C   1 
ATOM   4788 O O   . LEU B 1 283 ? 130.427 128.657 126.115 1.00 229.79 ?  283  LEU B O   1 
ATOM   4789 C CB  . LEU B 1 283 ? 130.736 126.426 128.605 1.00 229.79 ?  283  LEU B CB  1 
ATOM   4790 C CG  . LEU B 1 283 ? 129.860 125.448 127.821 1.00 229.79 ?  283  LEU B CG  1 
ATOM   4791 C CD1 . LEU B 1 283 ? 130.092 124.025 128.301 1.00 229.79 ?  283  LEU B CD1 1 
ATOM   4792 C CD2 . LEU B 1 283 ? 128.392 125.819 127.956 1.00 229.79 ?  283  LEU B CD2 1 
ATOM   4793 N N   . GLY B 1 284 ? 130.309 129.426 128.222 1.00 243.51 ?  284  GLY B N   1 
ATOM   4794 C CA  . GLY B 1 284 ? 129.474 130.553 127.852 1.00 243.51 ?  284  GLY B CA  1 
ATOM   4795 C C   . GLY B 1 284 ? 130.093 131.402 126.769 1.00 243.51 ?  284  GLY B C   1 
ATOM   4796 O O   . GLY B 1 284 ? 129.402 131.821 125.851 1.00 243.51 ?  284  GLY B O   1 
ATOM   4797 N N   . GLY B 1 285 ? 131.392 131.656 126.867 1.00 256.46 ?  285  GLY B N   1 
ATOM   4798 C CA  . GLY B 1 285 ? 132.080 132.447 125.866 1.00 256.46 ?  285  GLY B CA  1 
ATOM   4799 C C   . GLY B 1 285 ? 132.013 131.842 124.483 1.00 256.46 ?  285  GLY B C   1 
ATOM   4800 O O   . GLY B 1 285 ? 131.671 132.524 123.527 1.00 256.46 ?  285  GLY B O   1 
ATOM   4801 N N   . VAL B 1 286 ? 132.334 130.559 124.366 1.00 248.56 ?  286  VAL B N   1 
ATOM   4802 C CA  . VAL B 1 286 ? 132.260 129.886 123.074 1.00 248.56 ?  286  VAL B CA  1 
ATOM   4803 C C   . VAL B 1 286 ? 130.874 130.043 122.479 1.00 248.56 ?  286  VAL B C   1 
ATOM   4804 O O   . VAL B 1 286 ? 130.731 130.458 121.329 1.00 248.56 ?  286  VAL B O   1 
ATOM   4805 C CB  . VAL B 1 286 ? 132.603 128.391 123.190 1.00 248.56 ?  286  VAL B CB  1 
ATOM   4806 C CG1 . VAL B 1 286 ? 132.620 127.737 121.818 1.00 248.56 ?  286  VAL B CG1 1 
ATOM   4807 C CG2 . VAL B 1 286 ? 133.948 128.216 123.869 1.00 248.56 ?  286  VAL B CG2 1 
ATOM   4808 N N   . LEU B 1 287 ? 129.848 129.737 123.266 1.00 238.93 ?  287  LEU B N   1 
ATOM   4809 C CA  . LEU B 1 287 ? 128.476 129.846 122.784 1.00 238.93 ?  287  LEU B CA  1 
ATOM   4810 C C   . LEU B 1 287 ? 128.135 131.271 122.385 1.00 238.93 ?  287  LEU B C   1 
ATOM   4811 O O   . LEU B 1 287 ? 127.493 131.492 121.360 1.00 238.93 ?  287  LEU B O   1 
ATOM   4812 C CB  . LEU B 1 287 ? 127.503 129.339 123.842 1.00 238.93 ?  287  LEU B CB  1 
ATOM   4813 C CG  . LEU B 1 287 ? 126.931 127.944 123.595 1.00 238.93 ?  287  LEU B CG  1 
ATOM   4814 C CD1 . LEU B 1 287 ? 126.774 127.692 122.104 1.00 238.93 ?  287  LEU B CD1 1 
ATOM   4815 C CD2 . LEU B 1 287 ? 127.816 126.886 124.230 1.00 238.93 ?  287  LEU B CD2 1 
ATOM   4816 N N   . PHE B 1 288 ? 128.565 132.239 123.183 1.00 237.90 ?  288  PHE B N   1 
ATOM   4817 C CA  . PHE B 1 288 ? 128.322 133.638 122.862 1.00 237.90 ?  288  PHE B CA  1 
ATOM   4818 C C   . PHE B 1 288 ? 128.888 133.974 121.503 1.00 237.90 ?  288  PHE B C   1 
ATOM   4819 O O   . PHE B 1 288 ? 128.178 134.499 120.657 1.00 237.90 ?  288  PHE B O   1 
ATOM   4820 C CB  . PHE B 1 288 ? 128.938 134.548 123.919 1.00 237.90 ?  288  PHE B CB  1 
ATOM   4821 C CG  . PHE B 1 288 ? 128.563 135.991 123.768 1.00 237.90 ?  288  PHE B CG  1 
ATOM   4822 C CD1 . PHE B 1 288 ? 127.308 136.436 124.137 1.00 237.90 ?  288  PHE B CD1 1 
ATOM   4823 C CD2 . PHE B 1 288 ? 129.469 136.904 123.260 1.00 237.90 ?  288  PHE B CD2 1 
ATOM   4824 C CE1 . PHE B 1 288 ? 126.962 137.764 124.001 1.00 237.90 ?  288  PHE B CE1 1 
ATOM   4825 C CE2 . PHE B 1 288 ? 129.128 138.232 123.119 1.00 237.90 ?  288  PHE B CE2 1 
ATOM   4826 C CZ  . PHE B 1 288 ? 127.872 138.664 123.490 1.00 237.90 ?  288  PHE B CZ  1 
ATOM   4827 N N   . SER B 1 289 ? 130.161 133.669 121.288 1.00 247.17 ?  289  SER B N   1 
ATOM   4828 C CA  . SER B 1 289 ? 130.804 133.967 120.014 1.00 247.17 ?  289  SER B CA  1 
ATOM   4829 C C   . SER B 1 289 ? 130.051 133.361 118.847 1.00 247.17 ?  289  SER B C   1 
ATOM   4830 O O   . SER B 1 289 ? 129.803 134.032 117.854 1.00 247.17 ?  289  SER B O   1 
ATOM   4831 C CB  . SER B 1 289 ? 132.239 133.463 120.011 1.00 247.17 ?  289  SER B CB  1 
ATOM   4832 O OG  . SER B 1 289 ? 132.506 132.681 118.861 1.00 247.17 ?  289  SER B OG  1 
ATOM   4833 N N   . ILE B 1 290 ? 129.684 132.092 118.963 1.00 266.47 ?  290  ILE B N   1 
ATOM   4834 C CA  . ILE B 1 290 ? 128.944 131.429 117.901 1.00 266.47 ?  290  ILE B CA  1 
ATOM   4835 C C   . ILE B 1 290 ? 127.725 132.255 117.522 1.00 266.47 ?  290  ILE B C   1 
ATOM   4836 O O   . ILE B 1 290 ? 127.474 132.496 116.342 1.00 266.47 ?  290  ILE B O   1 
ATOM   4837 C CB  . ILE B 1 290 ? 128.522 130.013 118.339 1.00 266.47 ?  290  ILE B CB  1 
ATOM   4838 C CG1 . ILE B 1 290 ? 129.701 129.050 118.224 1.00 266.47 ?  290  ILE B CG1 1 
ATOM   4839 C CG2 . ILE B 1 290 ? 127.339 129.506 117.528 1.00 266.47 ?  290  ILE B CG2 1 
ATOM   4840 C CD1 . ILE B 1 290 ? 129.582 127.848 119.129 1.00 266.47 ?  290  ILE B CD1 1 
ATOM   4841 N N   . GLU B 1 291 ? 126.983 132.724 118.518 1.00 258.40 ?  291  GLU B N   1 
ATOM   4842 C CA  . GLU B 1 291 ? 125.772 133.489 118.252 1.00 258.40 ?  291  GLU B CA  1 
ATOM   4843 C C   . GLU B 1 291 ? 126.009 134.880 117.676 1.00 258.40 ?  291  GLU B C   1 
ATOM   4844 O O   . GLU B 1 291 ? 125.263 135.316 116.803 1.00 258.40 ?  291  GLU B O   1 
ATOM   4845 C CB  . GLU B 1 291 ? 124.932 133.583 119.521 1.00 258.40 ?  291  GLU B CB  1 
ATOM   4846 C CG  . GLU B 1 291 ? 123.978 132.419 119.705 1.00 258.40 ?  291  GLU B CG  1 
ATOM   4847 C CD  . GLU B 1 291 ? 123.752 132.082 121.161 1.00 258.40 ?  291  GLU B CD  1 
ATOM   4848 O OE1 . GLU B 1 291 ? 124.250 131.032 121.615 1.00 258.40 ?  291  GLU B OE1 1 
ATOM   4849 O OE2 . GLU B 1 291 ? 123.076 132.870 121.851 1.00 258.40 -1 291  GLU B OE2 1 
ATOM   4850 N N   . VAL B 1 292 ? 127.033 135.583 118.150 1.00 252.65 ?  292  VAL B N   1 
ATOM   4851 C CA  . VAL B 1 292 ? 127.256 136.953 117.691 1.00 252.65 ?  292  VAL B CA  1 
ATOM   4852 C C   . VAL B 1 292 ? 128.108 137.088 116.442 1.00 252.65 ?  292  VAL B C   1 
ATOM   4853 O O   . VAL B 1 292 ? 128.135 138.157 115.846 1.00 252.65 ?  292  VAL B O   1 
ATOM   4854 C CB  . VAL B 1 292 ? 127.890 137.851 118.772 1.00 252.65 ?  292  VAL B CB  1 
ATOM   4855 C CG1 . VAL B 1 292 ? 126.882 138.221 119.837 1.00 252.65 ?  292  VAL B CG1 1 
ATOM   4856 C CG2 . VAL B 1 292 ? 129.127 137.214 119.369 1.00 252.65 ?  292  VAL B CG2 1 
ATOM   4857 N N   . THR B 1 293 ? 128.822 136.040 116.046 1.00 257.68 ?  293  THR B N   1 
ATOM   4858 C CA  . THR B 1 293 ? 129.727 136.169 114.906 1.00 257.68 ?  293  THR B CA  1 
ATOM   4859 C C   . THR B 1 293 ? 129.399 135.246 113.751 1.00 257.68 ?  293  THR B C   1 
ATOM   4860 O O   . THR B 1 293 ? 130.118 135.229 112.756 1.00 257.68 ?  293  THR B O   1 
ATOM   4861 C CB  . THR B 1 293 ? 131.203 135.924 115.292 1.00 257.68 ?  293  THR B CB  1 
ATOM   4862 O OG1 . THR B 1 293 ? 131.387 134.550 115.654 1.00 257.68 ?  293  THR B OG1 1 
ATOM   4863 C CG2 . THR B 1 293 ? 131.629 136.820 116.445 1.00 257.68 ?  293  THR B CG2 1 
ATOM   4864 N N   . SER B 1 294 ? 128.328 134.475 113.869 1.00 249.50 ?  294  SER B N   1 
ATOM   4865 C CA  . SER B 1 294 ? 128.007 133.515 112.822 1.00 249.50 ?  294  SER B CA  1 
ATOM   4866 C C   . SER B 1 294 ? 126.522 133.339 112.592 1.00 249.50 ?  294  SER B C   1 
ATOM   4867 O O   . SER B 1 294 ? 125.727 133.484 113.517 1.00 249.50 ?  294  SER B O   1 
ATOM   4868 C CB  . SER B 1 294 ? 128.634 132.159 113.143 1.00 249.50 ?  294  SER B CB  1 
ATOM   4869 O OG  . SER B 1 294 ? 128.693 131.343 111.987 1.00 249.50 ?  294  SER B OG  1 
ATOM   4870 N N   . THR B 1 295 ? 126.140 133.031 111.358 1.00 214.64 ?  295  THR B N   1 
ATOM   4871 C CA  . THR B 1 295 ? 124.738 132.761 111.064 1.00 214.64 ?  295  THR B CA  1 
ATOM   4872 C C   . THR B 1 295 ? 124.570 131.259 110.925 1.00 214.64 ?  295  THR B C   1 
ATOM   4873 O O   . THR B 1 295 ? 123.501 130.724 111.209 1.00 214.64 ?  295  THR B O   1 
ATOM   4874 C CB  . THR B 1 295 ? 124.274 133.467 109.776 1.00 214.64 ?  295  THR B CB  1 
ATOM   4875 O OG1 . THR B 1 295 ? 123.042 132.890 109.328 1.00 214.64 ?  295  THR B OG1 1 
ATOM   4876 C CG2 . THR B 1 295 ? 125.320 133.338 108.676 1.00 214.64 ?  295  THR B CG2 1 
ATOM   4877 N N   . TYR B 1 296 ? 125.626 130.574 110.499 1.00 214.03 ?  296  TYR B N   1 
ATOM   4878 C CA  . TYR B 1 296 ? 125.586 129.126 110.344 1.00 214.03 ?  296  TYR B CA  1 
ATOM   4879 C C   . TYR B 1 296 ? 126.923 128.595 110.803 1.00 214.03 ?  296  TYR B C   1 
ATOM   4880 O O   . TYR B 1 296 ? 127.909 128.692 110.079 1.00 214.03 ?  296  TYR B O   1 
ATOM   4881 C CB  . TYR B 1 296 ? 125.375 128.746 108.879 1.00 214.03 ?  296  TYR B CB  1 
ATOM   4882 C CG  . TYR B 1 296 ? 123.953 128.891 108.398 1.00 214.03 ?  296  TYR B CG  1 
ATOM   4883 C CD1 . TYR B 1 296 ? 122.974 127.994 108.793 1.00 214.03 ?  296  TYR B CD1 1 
ATOM   4884 C CD2 . TYR B 1 296 ? 123.590 129.926 107.548 1.00 214.03 ?  296  TYR B CD2 1 
ATOM   4885 C CE1 . TYR B 1 296 ? 121.671 128.124 108.358 1.00 214.03 ?  296  TYR B CE1 1 
ATOM   4886 C CE2 . TYR B 1 296 ? 122.290 130.065 107.108 1.00 214.03 ?  296  TYR B CE2 1 
ATOM   4887 C CZ  . TYR B 1 296 ? 121.335 129.161 107.516 1.00 214.03 ?  296  TYR B CZ  1 
ATOM   4888 O OH  . TYR B 1 296 ? 120.037 129.291 107.081 1.00 214.03 ?  296  TYR B OH  1 
ATOM   4889 N N   . PHE B 1 297 ? 126.952 128.014 111.986 1.00 202.07 ?  297  PHE B N   1 
ATOM   4890 C CA  . PHE B 1 297 ? 128.199 127.547 112.553 1.00 202.07 ?  297  PHE B CA  1 
ATOM   4891 C C   . PHE B 1 297 ? 128.464 126.080 112.264 1.00 202.07 ?  297  PHE B C   1 
ATOM   4892 O O   . PHE B 1 297 ? 127.536 125.335 111.976 1.00 202.07 ?  297  PHE B O   1 
ATOM   4893 C CB  . PHE B 1 297 ? 128.099 127.772 114.044 1.00 202.07 ?  297  PHE B CB  1 
ATOM   4894 C CG  . PHE B 1 297 ? 129.398 127.963 114.707 1.00 202.07 ?  297  PHE B CG  1 
ATOM   4895 C CD1 . PHE B 1 297 ? 129.963 129.198 114.759 1.00 202.07 ?  297  PHE B CD1 1 
ATOM   4896 C CD2 . PHE B 1 297 ? 130.041 126.909 115.293 1.00 202.07 ?  297  PHE B CD2 1 
ATOM   4897 C CE1 . PHE B 1 297 ? 131.169 129.377 115.377 1.00 202.07 ?  297  PHE B CE1 1 
ATOM   4898 C CE2 . PHE B 1 297 ? 131.259 127.073 115.892 1.00 202.07 ?  297  PHE B CE2 1 
ATOM   4899 C CZ  . PHE B 1 297 ? 131.843 128.309 115.924 1.00 202.07 ?  297  PHE B CZ  1 
ATOM   4900 N N   . ALA B 1 298 ? 129.724 125.657 112.339 1.00 189.57 ?  298  ALA B N   1 
ATOM   4901 C CA  . ALA B 1 298 ? 130.030 124.249 112.155 1.00 189.57 ?  298  ALA B CA  1 
ATOM   4902 C C   . ALA B 1 298 ? 130.386 123.650 113.499 1.00 189.57 ?  298  ALA B C   1 
ATOM   4903 O O   . ALA B 1 298 ? 131.081 124.276 114.291 1.00 189.57 ?  298  ALA B O   1 
ATOM   4904 C CB  . ALA B 1 298 ? 131.174 124.087 111.179 1.00 189.57 ?  298  ALA B CB  1 
ATOM   4905 N N   . VAL B 1 299 ? 129.915 122.439 113.767 1.00 207.10 ?  299  VAL B N   1 
ATOM   4906 C CA  . VAL B 1 299 ? 130.168 121.809 115.058 1.00 207.10 ?  299  VAL B CA  1 
ATOM   4907 C C   . VAL B 1 299 ? 131.648 121.573 115.319 1.00 207.10 ?  299  VAL B C   1 
ATOM   4908 O O   . VAL B 1 299 ? 132.079 121.560 116.467 1.00 207.10 ?  299  VAL B O   1 
ATOM   4909 C CB  . VAL B 1 299 ? 129.406 120.484 115.198 1.00 207.10 ?  299  VAL B CB  1 
ATOM   4910 C CG1 . VAL B 1 299 ? 128.563 120.496 116.463 1.00 207.10 ?  299  VAL B CG1 1 
ATOM   4911 C CG2 . VAL B 1 299 ? 128.537 120.245 113.976 1.00 207.10 ?  299  VAL B CG2 1 
ATOM   4912 N N   . ARG B 1 300 ? 132.431 121.384 114.265 1.00 246.42 ?  300  ARG B N   1 
ATOM   4913 C CA  . ARG B 1 300 ? 133.867 121.225 114.438 1.00 246.42 ?  300  ARG B CA  1 
ATOM   4914 C C   . ARG B 1 300 ? 134.446 122.457 115.103 1.00 246.42 ?  300  ARG B C   1 
ATOM   4915 O O   . ARG B 1 300 ? 135.210 122.343 116.052 1.00 246.42 ?  300  ARG B O   1 
ATOM   4916 C CB  . ARG B 1 300 ? 134.557 120.978 113.097 1.00 246.42 ?  300  ARG B CB  1 
ATOM   4917 C CG  . ARG B 1 300 ? 133.863 121.597 111.897 1.00 246.42 ?  300  ARG B CG  1 
ATOM   4918 C CD  . ARG B 1 300 ? 134.806 122.515 111.139 1.00 246.42 ?  300  ARG B CD  1 
ATOM   4919 N NE  . ARG B 1 300 ? 134.744 122.293 109.698 1.00 246.42 ?  300  ARG B NE  1 
ATOM   4920 C CZ  . ARG B 1 300 ? 134.437 123.231 108.809 1.00 246.42 ?  300  ARG B CZ  1 
ATOM   4921 N NH1 . ARG B 1 300 ? 134.406 122.937 107.518 1.00 246.42 1  300  ARG B NH1 1 
ATOM   4922 N NH2 . ARG B 1 300 ? 134.162 124.463 109.210 1.00 246.42 ?  300  ARG B NH2 1 
ATOM   4923 N N   . ASN B 1 301 ? 134.072 123.637 114.619 1.00 242.46 ?  301  ASN B N   1 
ATOM   4924 C CA  . ASN B 1 301 ? 134.570 124.878 115.191 1.00 242.46 ?  301  ASN B CA  1 
ATOM   4925 C C   . ASN B 1 301 ? 134.116 125.056 116.629 1.00 242.46 ?  301  ASN B C   1 
ATOM   4926 O O   . ASN B 1 301 ? 134.816 125.672 117.426 1.00 242.46 ?  301  ASN B O   1 
ATOM   4927 C CB  . ASN B 1 301 ? 134.126 126.064 114.345 1.00 242.46 ?  301  ASN B CB  1 
ATOM   4928 C CG  . ASN B 1 301 ? 134.771 126.072 112.980 1.00 242.46 ?  301  ASN B CG  1 
ATOM   4929 O OD1 . ASN B 1 301 ? 135.844 125.503 112.790 1.00 242.46 ?  301  ASN B OD1 1 
ATOM   4930 N ND2 . ASN B 1 301 ? 134.121 126.714 112.020 1.00 242.46 ?  301  ASN B ND2 1 
ATOM   4931 N N   . TYR B 1 302 ? 132.951 124.520 116.969 1.00 189.18 ?  302  TYR B N   1 
ATOM   4932 C CA  . TYR B 1 302 ? 132.470 124.596 118.342 1.00 189.18 ?  302  TYR B CA  1 
ATOM   4933 C C   . TYR B 1 302 ? 133.412 123.828 119.248 1.00 189.18 ?  302  TYR B C   1 
ATOM   4934 O O   . TYR B 1 302 ? 133.857 124.346 120.269 1.00 189.18 ?  302  TYR B O   1 
ATOM   4935 C CB  . TYR B 1 302 ? 131.051 124.036 118.443 1.00 189.18 ?  302  TYR B CB  1 
ATOM   4936 C CG  . TYR B 1 302 ? 130.572 123.767 119.851 1.00 189.18 ?  302  TYR B CG  1 
ATOM   4937 C CD1 . TYR B 1 302 ? 130.505 124.784 120.791 1.00 189.18 ?  302  TYR B CD1 1 
ATOM   4938 C CD2 . TYR B 1 302 ? 130.176 122.496 120.235 1.00 189.18 ?  302  TYR B CD2 1 
ATOM   4939 C CE1 . TYR B 1 302 ? 130.069 124.542 122.078 1.00 189.18 ?  302  TYR B CE1 1 
ATOM   4940 C CE2 . TYR B 1 302 ? 129.737 122.243 121.519 1.00 189.18 ?  302  TYR B CE2 1 
ATOM   4941 C CZ  . TYR B 1 302 ? 129.684 123.270 122.435 1.00 189.18 ?  302  TYR B CZ  1 
ATOM   4942 O OH  . TYR B 1 302 ? 129.246 123.026 123.716 1.00 189.18 ?  302  TYR B OH  1 
ATOM   4943 N N   . TRP B 1 303 ? 133.730 122.596 118.873 1.00 253.38 ?  303  TRP B N   1 
ATOM   4944 C CA  . TRP B 1 303 ? 134.630 121.784 119.679 1.00 253.38 ?  303  TRP B CA  1 
ATOM   4945 C C   . TRP B 1 303 ? 136.008 122.413 119.762 1.00 253.38 ?  303  TRP B C   1 
ATOM   4946 O O   . TRP B 1 303 ? 136.620 122.430 120.825 1.00 253.38 ?  303  TRP B O   1 
ATOM   4947 C CB  . TRP B 1 303 ? 134.738 120.374 119.107 1.00 253.38 ?  303  TRP B CB  1 
ATOM   4948 C CG  . TRP B 1 303 ? 133.428 119.672 118.996 1.00 253.38 ?  303  TRP B CG  1 
ATOM   4949 C CD1 . TRP B 1 303 ? 132.384 119.740 119.870 1.00 253.38 ?  303  TRP B CD1 1 
ATOM   4950 C CD2 . TRP B 1 303 ? 133.017 118.786 117.950 1.00 253.38 ?  303  TRP B CD2 1 
ATOM   4951 N NE1 . TRP B 1 303 ? 131.346 118.957 119.431 1.00 253.38 ?  303  TRP B NE1 1 
ATOM   4952 C CE2 . TRP B 1 303 ? 131.710 118.359 118.254 1.00 253.38 ?  303  TRP B CE2 1 
ATOM   4953 C CE3 . TRP B 1 303 ? 133.626 118.315 116.784 1.00 253.38 ?  303  TRP B CE3 1 
ATOM   4954 C CZ2 . TRP B 1 303 ? 131.003 117.483 117.436 1.00 253.38 ?  303  TRP B CZ2 1 
ATOM   4955 C CZ3 . TRP B 1 303 ? 132.922 117.447 115.973 1.00 253.38 ?  303  TRP B CZ3 1 
ATOM   4956 C CH2 . TRP B 1 303 ? 131.625 117.040 116.302 1.00 253.38 ?  303  TRP B CH2 1 
ATOM   4957 N N   . ARG B 1 304 ? 136.500 122.931 118.645 1.00 260.72 ?  304  ARG B N   1 
ATOM   4958 C CA  . ARG B 1 304 ? 137.823 123.534 118.623 1.00 260.72 ?  304  ARG B CA  1 
ATOM   4959 C C   . ARG B 1 304 ? 137.868 124.751 119.524 1.00 260.72 ?  304  ARG B C   1 
ATOM   4960 O O   . ARG B 1 304 ? 138.806 124.919 120.298 1.00 260.72 ?  304  ARG B O   1 
ATOM   4961 C CB  . ARG B 1 304 ? 138.201 123.918 117.195 1.00 260.72 ?  304  ARG B CB  1 
ATOM   4962 C CG  . ARG B 1 304 ? 138.451 122.736 116.275 1.00 260.72 ?  304  ARG B CG  1 
ATOM   4963 C CD  . ARG B 1 304 ? 139.566 123.018 115.283 1.00 260.72 ?  304  ARG B CD  1 
ATOM   4964 N NE  . ARG B 1 304 ? 139.413 124.307 114.616 1.00 260.72 ?  304  ARG B NE  1 
ATOM   4965 C CZ  . ARG B 1 304 ? 140.431 125.056 114.204 1.00 260.72 ?  304  ARG B CZ  1 
ATOM   4966 N NH1 . ARG B 1 304 ? 141.676 124.646 114.395 1.00 260.72 1  304  ARG B NH1 1 
ATOM   4967 N NH2 . ARG B 1 304 ? 140.207 126.216 113.604 1.00 260.72 ?  304  ARG B NH2 1 
ATOM   4968 N N   . GLY B 1 305 ? 136.852 125.598 119.436 1.00 246.55 ?  305  GLY B N   1 
ATOM   4969 C CA  . GLY B 1 305 ? 136.795 126.782 120.269 1.00 246.55 ?  305  GLY B CA  1 
ATOM   4970 C C   . GLY B 1 305 ? 136.715 126.423 121.731 1.00 246.55 ?  305  GLY B C   1 
ATOM   4971 O O   . GLY B 1 305 ? 137.331 127.077 122.561 1.00 246.55 ?  305  GLY B O   1 
ATOM   4972 N N   . PHE B 1 306 ? 135.967 125.375 122.052 1.00 235.42 ?  306  PHE B N   1 
ATOM   4973 C CA  . PHE B 1 306 ? 135.842 124.937 123.433 1.00 235.42 ?  306  PHE B CA  1 
ATOM   4974 C C   . PHE B 1 306 ? 137.169 124.437 123.985 1.00 235.42 ?  306  PHE B C   1 
ATOM   4975 O O   . PHE B 1 306 ? 137.526 124.750 125.114 1.00 235.42 ?  306  PHE B O   1 
ATOM   4976 C CB  . PHE B 1 306 ? 134.773 123.852 123.557 1.00 235.42 ?  306  PHE B CB  1 
ATOM   4977 C CG  . PHE B 1 306 ? 134.400 123.535 124.973 1.00 235.42 ?  306  PHE B CG  1 
ATOM   4978 C CD1 . PHE B 1 306 ? 134.044 124.546 125.850 1.00 235.42 ?  306  PHE B CD1 1 
ATOM   4979 C CD2 . PHE B 1 306 ? 134.411 122.230 125.429 1.00 235.42 ?  306  PHE B CD2 1 
ATOM   4980 C CE1 . PHE B 1 306 ? 133.706 124.258 127.156 1.00 235.42 ?  306  PHE B CE1 1 
ATOM   4981 C CE2 . PHE B 1 306 ? 134.072 121.935 126.735 1.00 235.42 ?  306  PHE B CE2 1 
ATOM   4982 C CZ  . PHE B 1 306 ? 133.717 122.951 127.600 1.00 235.42 ?  306  PHE B CZ  1 
ATOM   4983 N N   . PHE B 1 307 ? 137.905 123.669 123.191 1.00 255.37 ?  307  PHE B N   1 
ATOM   4984 C CA  . PHE B 1 307 ? 139.198 123.164 123.631 1.00 255.37 ?  307  PHE B CA  1 
ATOM   4985 C C   . PHE B 1 307 ? 140.155 124.309 123.905 1.00 255.37 ?  307  PHE B C   1 
ATOM   4986 O O   . PHE B 1 307 ? 140.835 124.332 124.929 1.00 255.37 ?  307  PHE B O   1 
ATOM   4987 C CB  . PHE B 1 307 ? 139.800 122.225 122.589 1.00 255.37 ?  307  PHE B CB  1 
ATOM   4988 C CG  . PHE B 1 307 ? 141.168 121.723 122.948 1.00 255.37 ?  307  PHE B CG  1 
ATOM   4989 C CD1 . PHE B 1 307 ? 141.360 120.948 124.078 1.00 255.37 ?  307  PHE B CD1 1 
ATOM   4990 C CD2 . PHE B 1 307 ? 142.262 122.031 122.162 1.00 255.37 ?  307  PHE B CD2 1 
ATOM   4991 C CE1 . PHE B 1 307 ? 142.619 120.489 124.414 1.00 255.37 ?  307  PHE B CE1 1 
ATOM   4992 C CE2 . PHE B 1 307 ? 143.522 121.576 122.489 1.00 255.37 ?  307  PHE B CE2 1 
ATOM   4993 C CZ  . PHE B 1 307 ? 143.701 120.803 123.617 1.00 255.37 ?  307  PHE B CZ  1 
ATOM   4994 N N   . ALA B 1 308 ? 140.209 125.267 122.993 1.00 251.09 ?  308  ALA B N   1 
ATOM   4995 C CA  . ALA B 1 308 ? 141.113 126.386 123.165 1.00 251.09 ?  308  ALA B CA  1 
ATOM   4996 C C   . ALA B 1 308 ? 140.712 127.242 124.358 1.00 251.09 ?  308  ALA B C   1 
ATOM   4997 O O   . ALA B 1 308 ? 141.570 127.756 125.070 1.00 251.09 ?  308  ALA B O   1 
ATOM   4998 C CB  . ALA B 1 308 ? 141.158 127.210 121.899 1.00 251.09 ?  308  ALA B CB  1 
ATOM   4999 N N   . ALA B 1 309 ? 139.414 127.382 124.593 1.00 248.92 ?  309  ALA B N   1 
ATOM   5000 C CA  . ALA B 1 309 ? 138.937 128.188 125.709 1.00 248.92 ?  309  ALA B CA  1 
ATOM   5001 C C   . ALA B 1 309 ? 139.148 127.505 127.051 1.00 248.92 ?  309  ALA B C   1 
ATOM   5002 O O   . ALA B 1 309 ? 139.318 128.175 128.065 1.00 248.92 ?  309  ALA B O   1 
ATOM   5003 C CB  . ALA B 1 309 ? 137.475 128.547 125.520 1.00 248.92 ?  309  ALA B CB  1 
ATOM   5004 N N   . THR B 1 310 ? 139.139 126.178 127.071 1.00 278.73 ?  310  THR B N   1 
ATOM   5005 C CA  . THR B 1 310 ? 139.407 125.469 128.315 1.00 278.73 ?  310  THR B CA  1 
ATOM   5006 C C   . THR B 1 310 ? 140.878 125.559 128.643 1.00 278.73 ?  310  THR B C   1 
ATOM   5007 O O   . THR B 1 310 ? 141.251 125.559 129.810 1.00 278.73 ?  310  THR B O   1 
ATOM   5008 C CB  . THR B 1 310 ? 138.973 123.993 128.279 1.00 278.73 ?  310  THR B CB  1 
ATOM   5009 O OG1 . THR B 1 310 ? 139.418 123.383 127.064 1.00 278.73 ?  310  THR B OG1 1 
ATOM   5010 C CG2 . THR B 1 310 ? 137.463 123.882 128.379 1.00 278.73 ?  310  THR B CG2 1 
ATOM   5011 N N   . PHE B 1 311 ? 141.724 125.646 127.625 1.00 245.67 ?  311  PHE B N   1 
ATOM   5012 C CA  . PHE B 1 311 ? 143.141 125.829 127.890 1.00 245.67 ?  311  PHE B CA  1 
ATOM   5013 C C   . PHE B 1 311 ? 143.372 127.237 128.401 1.00 245.67 ?  311  PHE B C   1 
ATOM   5014 O O   . PHE B 1 311 ? 144.214 127.450 129.261 1.00 245.67 ?  311  PHE B O   1 
ATOM   5015 C CB  . PHE B 1 311 ? 143.996 125.555 126.657 1.00 245.67 ?  311  PHE B CB  1 
ATOM   5016 C CG  . PHE B 1 311 ? 145.438 125.307 126.979 1.00 245.67 ?  311  PHE B CG  1 
ATOM   5017 C CD1 . PHE B 1 311 ? 145.844 124.086 127.484 1.00 245.67 ?  311  PHE B CD1 1 
ATOM   5018 C CD2 . PHE B 1 311 ? 146.382 126.301 126.805 1.00 245.67 ?  311  PHE B CD2 1 
ATOM   5019 C CE1 . PHE B 1 311 ? 147.169 123.854 127.794 1.00 245.67 ?  311  PHE B CE1 1 
ATOM   5020 C CE2 . PHE B 1 311 ? 147.709 126.078 127.114 1.00 245.67 ?  311  PHE B CE2 1 
ATOM   5021 C CZ  . PHE B 1 311 ? 148.103 124.853 127.610 1.00 245.67 ?  311  PHE B CZ  1 
ATOM   5022 N N   . SER B 1 312 ? 142.621 128.202 127.884 1.00 245.26 ?  312  SER B N   1 
ATOM   5023 C CA  . SER B 1 312 ? 142.734 129.571 128.371 1.00 245.26 ?  312  SER B CA  1 
ATOM   5024 C C   . SER B 1 312 ? 142.373 129.600 129.841 1.00 245.26 ?  312  SER B C   1 
ATOM   5025 O O   . SER B 1 312 ? 143.056 130.233 130.638 1.00 245.26 ?  312  SER B O   1 
ATOM   5026 C CB  . SER B 1 312 ? 141.813 130.498 127.582 1.00 245.26 ?  312  SER B CB  1 
ATOM   5027 O OG  . SER B 1 312 ? 142.475 131.692 127.212 1.00 245.26 ?  312  SER B OG  1 
ATOM   5028 N N   . ALA B 1 313 ? 141.308 128.901 130.208 1.00 226.87 ?  313  ALA B N   1 
ATOM   5029 C CA  . ALA B 1 313 ? 140.892 128.848 131.602 1.00 226.87 ?  313  ALA B CA  1 
ATOM   5030 C C   . ALA B 1 313 ? 141.917 128.130 132.457 1.00 226.87 ?  313  ALA B C   1 
ATOM   5031 O O   . ALA B 1 313 ? 142.140 128.507 133.600 1.00 226.87 ?  313  ALA B O   1 
ATOM   5032 C CB  . ALA B 1 313 ? 139.543 128.171 131.721 1.00 226.87 ?  313  ALA B CB  1 
ATOM   5033 N N   . PHE B 1 314 ? 142.539 127.093 131.912 1.00 245.76 ?  314  PHE B N   1 
ATOM   5034 C CA  . PHE B 1 314 ? 143.569 126.373 132.643 1.00 245.76 ?  314  PHE B CA  1 
ATOM   5035 C C   . PHE B 1 314 ? 144.712 127.316 132.966 1.00 245.76 ?  314  PHE B C   1 
ATOM   5036 O O   . PHE B 1 314 ? 145.170 127.371 134.102 1.00 245.76 ?  314  PHE B O   1 
ATOM   5037 C CB  . PHE B 1 314 ? 144.061 125.181 131.821 1.00 245.76 ?  314  PHE B CB  1 
ATOM   5038 C CG  . PHE B 1 314 ? 145.384 124.631 132.267 1.00 245.76 ?  314  PHE B CG  1 
ATOM   5039 C CD1 . PHE B 1 314 ? 145.492 123.926 133.453 1.00 245.76 ?  314  PHE B CD1 1 
ATOM   5040 C CD2 . PHE B 1 314 ? 146.517 124.804 131.490 1.00 245.76 ?  314  PHE B CD2 1 
ATOM   5041 C CE1 . PHE B 1 314 ? 146.707 123.415 133.863 1.00 245.76 ?  314  PHE B CE1 1 
ATOM   5042 C CE2 . PHE B 1 314 ? 147.735 124.298 131.894 1.00 245.76 ?  314  PHE B CE2 1 
ATOM   5043 C CZ  . PHE B 1 314 ? 147.830 123.601 133.082 1.00 245.76 ?  314  PHE B CZ  1 
ATOM   5044 N N   . VAL B 1 315 ? 145.169 128.069 131.972 1.00 246.86 ?  315  VAL B N   1 
ATOM   5045 C CA  . VAL B 1 315 ? 146.261 129.007 132.189 1.00 246.86 ?  315  VAL B CA  1 
ATOM   5046 C C   . VAL B 1 315 ? 145.850 130.047 133.214 1.00 246.86 ?  315  VAL B C   1 
ATOM   5047 O O   . VAL B 1 315 ? 146.635 130.405 134.080 1.00 246.86 ?  315  VAL B O   1 
ATOM   5048 C CB  . VAL B 1 315 ? 146.708 129.674 130.875 1.00 246.86 ?  315  VAL B CB  1 
ATOM   5049 C CG1 . VAL B 1 315 ? 147.860 130.635 131.120 1.00 246.86 ?  315  VAL B CG1 1 
ATOM   5050 C CG2 . VAL B 1 315 ? 147.133 128.616 129.874 1.00 246.86 ?  315  VAL B CG2 1 
ATOM   5051 N N   . PHE B 1 316 ? 144.609 130.509 133.144 1.00 202.01 ?  316  PHE B N   1 
ATOM   5052 C CA  . PHE B 1 316 ? 144.116 131.479 134.113 1.00 202.01 ?  316  PHE B CA  1 
ATOM   5053 C C   . PHE B 1 316 ? 144.176 130.944 135.534 1.00 202.01 ?  316  PHE B C   1 
ATOM   5054 O O   . PHE B 1 316 ? 144.514 131.677 136.456 1.00 202.01 ?  316  PHE B O   1 
ATOM   5055 C CB  . PHE B 1 316 ? 142.686 131.885 133.780 1.00 202.01 ?  316  PHE B CB  1 
ATOM   5056 C CG  . PHE B 1 316 ? 142.591 133.101 132.912 1.00 202.01 ?  316  PHE B CG  1 
ATOM   5057 C CD1 . PHE B 1 316 ? 143.382 134.208 133.162 1.00 202.01 ?  316  PHE B CD1 1 
ATOM   5058 C CD2 . PHE B 1 316 ? 141.710 133.137 131.848 1.00 202.01 ?  316  PHE B CD2 1 
ATOM   5059 C CE1 . PHE B 1 316 ? 143.294 135.331 132.366 1.00 202.01 ?  316  PHE B CE1 1 
ATOM   5060 C CE2 . PHE B 1 316 ? 141.619 134.255 131.047 1.00 202.01 ?  316  PHE B CE2 1 
ATOM   5061 C CZ  . PHE B 1 316 ? 142.411 135.354 131.307 1.00 202.01 ?  316  PHE B CZ  1 
ATOM   5062 N N   . ARG B 1 317 ? 143.849 129.670 135.717 1.00 206.32 ?  317  ARG B N   1 
ATOM   5063 C CA  . ARG B 1 317 ? 143.892 129.064 137.045 1.00 206.32 ?  317  ARG B CA  1 
ATOM   5064 C C   . ARG B 1 317 ? 145.321 128.991 137.546 1.00 206.32 ?  317  ARG B C   1 
ATOM   5065 O O   . ARG B 1 317 ? 145.585 129.266 138.711 1.00 206.32 ?  317  ARG B O   1 
ATOM   5066 C CB  . ARG B 1 317 ? 143.279 127.664 137.031 1.00 206.32 ?  317  ARG B CB  1 
ATOM   5067 C CG  . ARG B 1 317 ? 141.783 127.626 136.767 1.00 206.32 ?  317  ARG B CG  1 
ATOM   5068 C CD  . ARG B 1 317 ? 141.078 128.855 137.314 1.00 206.32 ?  317  ARG B CD  1 
ATOM   5069 N NE  . ARG B 1 317 ? 139.682 128.584 137.640 1.00 206.32 ?  317  ARG B NE  1 
ATOM   5070 C CZ  . ARG B 1 317 ? 139.111 128.914 138.793 1.00 206.32 ?  317  ARG B CZ  1 
ATOM   5071 N NH1 . ARG B 1 317 ? 139.818 129.530 139.731 1.00 206.32 1  317  ARG B NH1 1 
ATOM   5072 N NH2 . ARG B 1 317 ? 137.834 128.630 139.009 1.00 206.32 ?  317  ARG B NH2 1 
ATOM   5073 N N   . VAL B 1 318 ? 146.247 128.620 136.670 1.00 221.29 ?  318  VAL B N   1 
ATOM   5074 C CA  . VAL B 1 318 ? 147.651 128.565 137.051 1.00 221.29 ?  318  VAL B CA  1 
ATOM   5075 C C   . VAL B 1 318 ? 148.156 129.961 137.390 1.00 221.29 ?  318  VAL B C   1 
ATOM   5076 O O   . VAL B 1 318 ? 148.865 130.146 138.377 1.00 221.29 ?  318  VAL B O   1 
ATOM   5077 C CB  . VAL B 1 318 ? 148.504 127.949 135.931 1.00 221.29 ?  318  VAL B CB  1 
ATOM   5078 C CG1 . VAL B 1 318 ? 149.966 127.890 136.336 1.00 221.29 ?  318  VAL B CG1 1 
ATOM   5079 C CG2 . VAL B 1 318 ? 148.001 126.557 135.599 1.00 221.29 ?  318  VAL B CG2 1 
ATOM   5080 N N   . LEU B 1 319 ? 147.773 130.951 136.591 1.00 214.33 ?  319  LEU B N   1 
ATOM   5081 C CA  . LEU B 1 319 ? 148.189 132.324 136.846 1.00 214.33 ?  319  LEU B CA  1 
ATOM   5082 C C   . LEU B 1 319 ? 147.629 132.808 138.168 1.00 214.33 ?  319  LEU B C   1 
ATOM   5083 O O   . LEU B 1 319 ? 148.283 133.563 138.880 1.00 214.33 ?  319  LEU B O   1 
ATOM   5084 C CB  . LEU B 1 319 ? 147.727 133.246 135.721 1.00 214.33 ?  319  LEU B CB  1 
ATOM   5085 C CG  . LEU B 1 319 ? 148.601 133.313 134.471 1.00 214.33 ?  319  LEU B CG  1 
ATOM   5086 C CD1 . LEU B 1 319 ? 147.782 133.797 133.285 1.00 214.33 ?  319  LEU B CD1 1 
ATOM   5087 C CD2 . LEU B 1 319 ? 149.796 134.222 134.709 1.00 214.33 ?  319  LEU B CD2 1 
ATOM   5088 N N   . ALA B 1 320 ? 146.425 132.362 138.504 1.00 212.63 ?  320  ALA B N   1 
ATOM   5089 C CA  . ALA B 1 320 ? 145.820 132.744 139.770 1.00 212.63 ?  320  ALA B CA  1 
ATOM   5090 C C   . ALA B 1 320 ? 146.661 132.211 140.907 1.00 212.63 ?  320  ALA B C   1 
ATOM   5091 O O   . ALA B 1 320 ? 147.019 132.952 141.811 1.00 212.63 ?  320  ALA B O   1 
ATOM   5092 C CB  . ALA B 1 320 ? 144.400 132.219 139.866 1.00 212.63 ?  320  ALA B CB  1 
ATOM   5093 N N   . VAL B 1 321 ? 146.990 130.928 140.861 1.00 232.14 ?  321  VAL B N   1 
ATOM   5094 C CA  . VAL B 1 321 ? 147.826 130.334 141.894 1.00 232.14 ?  321  VAL B CA  1 
ATOM   5095 C C   . VAL B 1 321 ? 149.127 131.108 142.013 1.00 232.14 ?  321  VAL B C   1 
ATOM   5096 O O   . VAL B 1 321 ? 149.517 131.512 143.109 1.00 232.14 ?  321  VAL B O   1 
ATOM   5097 C CB  . VAL B 1 321 ? 148.119 128.853 141.589 1.00 232.14 ?  321  VAL B CB  1 
ATOM   5098 C CG1 . VAL B 1 321 ? 149.139 128.287 142.566 1.00 232.14 ?  321  VAL B CG1 1 
ATOM   5099 C CG2 . VAL B 1 321 ? 146.834 128.043 141.635 1.00 232.14 ?  321  VAL B CG2 1 
ATOM   5100 N N   . TRP B 1 322 ? 149.755 131.397 140.882 1.00 263.41 ?  322  TRP B N   1 
ATOM   5101 C CA  . TRP B 1 322 ? 151.024 132.118 140.883 1.00 263.41 ?  322  TRP B CA  1 
ATOM   5102 C C   . TRP B 1 322 ? 150.966 133.499 141.497 1.00 263.41 ?  322  TRP B C   1 
ATOM   5103 O O   . TRP B 1 322 ? 151.730 133.802 142.409 1.00 263.41 ?  322  TRP B O   1 
ATOM   5104 C CB  . TRP B 1 322 ? 151.518 132.277 139.452 1.00 263.41 ?  322  TRP B CB  1 
ATOM   5105 C CG  . TRP B 1 322 ? 152.195 131.089 138.897 1.00 263.41 ?  322  TRP B CG  1 
ATOM   5106 C CD1 . TRP B 1 322 ? 152.723 130.043 139.591 1.00 263.41 ?  322  TRP B CD1 1 
ATOM   5107 C CD2 . TRP B 1 322 ? 152.433 130.820 137.516 1.00 263.41 ?  322  TRP B CD2 1 
ATOM   5108 N NE1 . TRP B 1 322 ? 153.275 129.133 138.723 1.00 263.41 ?  322  TRP B NE1 1 
ATOM   5109 C CE2 . TRP B 1 322 ? 153.111 129.589 137.442 1.00 263.41 ?  322  TRP B CE2 1 
ATOM   5110 C CE3 . TRP B 1 322 ? 152.138 131.501 136.333 1.00 263.41 ?  322  TRP B CE3 1 
ATOM   5111 C CZ2 . TRP B 1 322 ? 153.500 129.025 136.230 1.00 263.41 ?  322  TRP B CZ2 1 
ATOM   5112 C CZ3 . TRP B 1 322 ? 152.521 130.940 135.132 1.00 263.41 ?  322  TRP B CZ3 1 
ATOM   5113 C CH2 . TRP B 1 322 ? 153.195 129.714 135.088 1.00 263.41 ?  322  TRP B CH2 1 
ATOM   5114 N N   . ASN B 1 323 ? 150.071 134.349 141.010 1.00 237.10 ?  323  ASN B N   1 
ATOM   5115 C CA  . ASN B 1 323 ? 150.058 135.736 141.475 1.00 237.10 ?  323  ASN B CA  1 
ATOM   5116 C C   . ASN B 1 323 ? 148.960 136.132 142.448 1.00 237.10 ?  323  ASN B C   1 
ATOM   5117 O O   . ASN B 1 323 ? 148.843 137.312 142.774 1.00 237.10 ?  323  ASN B O   1 
ATOM   5118 C CB  . ASN B 1 323 ? 150.032 136.675 140.269 1.00 237.10 ?  323  ASN B CB  1 
ATOM   5119 C CG  . ASN B 1 323 ? 150.988 136.242 139.175 1.00 237.10 ?  323  ASN B CG  1 
ATOM   5120 O OD1 . ASN B 1 323 ? 150.603 135.547 138.234 1.00 237.10 ?  323  ASN B OD1 1 
ATOM   5121 N ND2 . ASN B 1 323 ? 152.243 136.655 139.292 1.00 237.10 ?  323  ASN B ND2 1 
ATOM   5122 N N   . LYS B 1 324 ? 148.192 135.161 142.930 1.00 232.23 ?  324  LYS B N   1 
ATOM   5123 C CA  . LYS B 1 324 ? 147.126 135.414 143.912 1.00 232.23 ?  324  LYS B CA  1 
ATOM   5124 C C   . LYS B 1 324 ? 146.271 136.635 143.645 1.00 232.23 ?  324  LYS B C   1 
ATOM   5125 O O   . LYS B 1 324 ? 145.401 136.592 142.778 1.00 232.23 ?  324  LYS B O   1 
ATOM   5126 C CB  . LYS B 1 324 ? 147.696 135.443 145.332 1.00 232.23 ?  324  LYS B CB  1 
ATOM   5127 C CG  . LYS B 1 324 ? 147.832 134.062 145.948 1.00 232.23 ?  324  LYS B CG  1 
ATOM   5128 C CD  . LYS B 1 324 ? 146.660 133.177 145.554 1.00 232.23 ?  324  LYS B CD  1 
ATOM   5129 C CE  . LYS B 1 324 ? 147.018 131.703 145.632 1.00 232.23 ?  324  LYS B CE  1 
ATOM   5130 N NZ  . LYS B 1 324 ? 146.007 130.864 144.933 1.00 232.23 1  324  LYS B NZ  1 
ATOM   5131 N N   . ASP B 1 325 ? 146.501 137.709 144.395 1.00 221.52 ?  325  ASP B N   1 
ATOM   5132 C CA  . ASP B 1 325 ? 145.728 138.941 144.234 1.00 221.52 ?  325  ASP B CA  1 
ATOM   5133 C C   . ASP B 1 325 ? 145.706 139.436 142.800 1.00 221.52 ?  325  ASP B C   1 
ATOM   5134 O O   . ASP B 1 325 ? 144.664 139.343 142.147 1.00 221.52 ?  325  ASP B O   1 
ATOM   5135 C CB  . ASP B 1 325 ? 146.308 140.025 145.140 1.00 221.52 ?  325  ASP B CB  1 
ATOM   5136 C CG  . ASP B 1 325 ? 147.692 139.671 145.649 1.00 221.52 ?  325  ASP B CG  1 
ATOM   5137 O OD1 . ASP B 1 325 ? 148.672 139.883 144.905 1.00 221.52 ?  325  ASP B OD1 1 
ATOM   5138 O OD2 . ASP B 1 325 ? 147.799 139.174 146.790 1.00 221.52 -1 325  ASP B OD2 1 
ATOM   5139 N N   . ALA B 1 326 ? 146.827 139.981 142.323 1.00 234.28 ?  326  ALA B N   1 
ATOM   5140 C CA  . ALA B 1 326 ? 146.938 140.457 140.938 1.00 234.28 ?  326  ALA B CA  1 
ATOM   5141 C C   . ALA B 1 326 ? 145.657 141.035 140.370 1.00 234.28 ?  326  ALA B C   1 
ATOM   5142 O O   . ALA B 1 326 ? 145.201 142.097 140.798 1.00 234.28 ?  326  ALA B O   1 
ATOM   5143 C CB  . ALA B 1 326 ? 147.428 139.327 140.055 1.00 234.28 ?  326  ALA B CB  1 
ATOM   5144 N N   . VAL B 1 327 ? 145.083 140.357 139.384 1.00 229.27 ?  327  VAL B N   1 
ATOM   5145 C CA  . VAL B 1 327 ? 143.796 140.787 138.859 1.00 229.27 ?  327  VAL B CA  1 
ATOM   5146 C C   . VAL B 1 327 ? 142.824 139.669 139.192 1.00 229.27 ?  327  VAL B C   1 
ATOM   5147 O O   . VAL B 1 327 ? 143.115 138.493 138.962 1.00 229.27 ?  327  VAL B O   1 
ATOM   5148 C CB  . VAL B 1 327 ? 143.840 141.071 137.342 1.00 229.27 ?  327  VAL B CB  1 
ATOM   5149 C CG1 . VAL B 1 327 ? 144.702 140.062 136.607 1.00 229.27 ?  327  VAL B CG1 1 
ATOM   5150 C CG2 . VAL B 1 327 ? 142.446 141.154 136.738 1.00 229.27 ?  327  VAL B CG2 1 
ATOM   5151 N N   . THR B 1 328 ? 141.693 140.006 139.793 1.00 244.65 ?  328  THR B N   1 
ATOM   5152 C CA  . THR B 1 328 ? 140.691 138.991 140.056 1.00 244.65 ?  328  THR B CA  1 
ATOM   5153 C C   . THR B 1 328 ? 139.874 138.865 138.794 1.00 244.65 ?  328  THR B C   1 
ATOM   5154 O O   . THR B 1 328 ? 138.832 139.504 138.675 1.00 244.65 ?  328  THR B O   1 
ATOM   5155 C CB  . THR B 1 328 ? 139.785 139.390 141.222 1.00 244.65 ?  328  THR B CB  1 
ATOM   5156 O OG1 . THR B 1 328 ? 139.999 140.772 141.534 1.00 244.65 ?  328  THR B OG1 1 
ATOM   5157 C CG2 . THR B 1 328 ? 140.096 138.548 142.445 1.00 244.65 ?  328  THR B CG2 1 
ATOM   5158 N N   . ILE B 1 329 ? 140.350 138.065 137.843 1.00 242.79 ?  329  ILE B N   1 
ATOM   5159 C CA  . ILE B 1 329 ? 139.667 137.912 136.563 1.00 242.79 ?  329  ILE B CA  1 
ATOM   5160 C C   . ILE B 1 329 ? 138.257 137.418 136.770 1.00 242.79 ?  329  ILE B C   1 
ATOM   5161 O O   . ILE B 1 329 ? 138.056 136.224 136.995 1.00 242.79 ?  329  ILE B O   1 
ATOM   5162 C CB  . ILE B 1 329 ? 140.410 136.927 135.639 1.00 242.79 ?  329  ILE B CB  1 
ATOM   5163 C CG1 . ILE B 1 329 ? 141.924 137.032 135.847 1.00 242.79 ?  329  ILE B CG1 1 
ATOM   5164 C CG2 . ILE B 1 329 ? 140.047 137.185 134.184 1.00 242.79 ?  329  ILE B CG2 1 
ATOM   5165 C CD1 . ILE B 1 329 ? 142.558 135.788 136.435 1.00 242.79 ?  329  ILE B CD1 1 
ATOM   5166 N N   . THR B 1 330 ? 137.281 138.324 136.708 1.00 225.17 ?  330  THR B N   1 
ATOM   5167 C CA  . THR B 1 330 ? 135.871 137.975 136.909 1.00 225.17 ?  330  THR B CA  1 
ATOM   5168 C C   . THR B 1 330 ? 135.590 137.008 138.063 1.00 225.17 ?  330  THR B C   1 
ATOM   5169 O O   . THR B 1 330 ? 134.706 136.163 137.969 1.00 225.17 ?  330  THR B O   1 
ATOM   5170 C CB  . THR B 1 330 ? 135.222 137.494 135.595 1.00 225.17 ?  330  THR B CB  1 
ATOM   5171 O OG1 . THR B 1 330 ? 135.714 136.192 135.251 1.00 225.17 ?  330  THR B OG1 1 
ATOM   5172 C CG2 . THR B 1 330 ? 135.531 138.468 134.468 1.00 225.17 ?  330  THR B CG2 1 
ATOM   5173 N N   . ALA B 1 331 ? 136.320 137.153 139.164 1.00 212.90 ?  331  ALA B N   1 
ATOM   5174 C CA  . ALA B 1 331 ? 136.137 136.264 140.304 1.00 212.90 ?  331  ALA B CA  1 
ATOM   5175 C C   . ALA B 1 331 ? 135.337 136.987 141.362 1.00 212.90 ?  331  ALA B C   1 
ATOM   5176 O O   . ALA B 1 331 ? 134.900 136.384 142.340 1.00 212.90 ?  331  ALA B O   1 
ATOM   5177 C CB  . ALA B 1 331 ? 137.480 135.823 140.856 1.00 212.90 ?  331  ALA B CB  1 
ATOM   5178 N N   . LEU B 1 332 ? 135.131 138.285 141.164 1.00 197.67 ?  332  LEU B N   1 
ATOM   5179 C CA  . LEU B 1 332 ? 134.334 139.060 142.102 1.00 197.67 ?  332  LEU B CA  1 
ATOM   5180 C C   . LEU B 1 332 ? 132.871 138.876 141.785 1.00 197.67 ?  332  LEU B C   1 
ATOM   5181 O O   . LEU B 1 332 ? 132.005 139.240 142.578 1.00 197.67 ?  332  LEU B O   1 
ATOM   5182 C CB  . LEU B 1 332 ? 134.676 140.539 141.988 1.00 197.67 ?  332  LEU B CB  1 
ATOM   5183 C CG  . LEU B 1 332 ? 136.127 140.905 141.704 1.00 197.67 ?  332  LEU B CG  1 
ATOM   5184 C CD1 . LEU B 1 332 ? 136.183 141.983 140.637 1.00 197.67 ?  332  LEU B CD1 1 
ATOM   5185 C CD2 . LEU B 1 332 ? 136.775 141.394 142.987 1.00 197.67 ?  332  LEU B CD2 1 
ATOM   5186 N N   . PHE B 1 333 ? 132.583 138.302 140.624 1.00 196.18 ?  333  PHE B N   1 
ATOM   5187 C CA  . PHE B 1 333 ? 131.199 138.151 140.210 1.00 196.18 ?  333  PHE B CA  1 
ATOM   5188 C C   . PHE B 1 333 ? 130.691 136.809 140.682 1.00 196.18 ?  333  PHE B C   1 
ATOM   5189 O O   . PHE B 1 333 ? 129.534 136.473 140.459 1.00 196.18 ?  333  PHE B O   1 
ATOM   5190 C CB  . PHE B 1 333 ? 131.054 138.287 138.693 1.00 196.18 ?  333  PHE B CB  1 
ATOM   5191 C CG  . PHE B 1 333 ? 131.734 139.503 138.116 1.00 196.18 ?  333  PHE B CG  1 
ATOM   5192 C CD1 . PHE B 1 333 ? 131.852 140.680 138.842 1.00 196.18 ?  333  PHE B CD1 1 
ATOM   5193 C CD2 . PHE B 1 333 ? 132.238 139.470 136.832 1.00 196.18 ?  333  PHE B CD2 1 
ATOM   5194 C CE1 . PHE B 1 333 ? 132.489 141.778 138.311 1.00 196.18 ?  333  PHE B CE1 1 
ATOM   5195 C CE2 . PHE B 1 333 ? 132.862 140.574 136.289 1.00 196.18 ?  333  PHE B CE2 1 
ATOM   5196 C CZ  . PHE B 1 333 ? 132.985 141.729 137.029 1.00 196.18 ?  333  PHE B CZ  1 
ATOM   5197 N N   . ARG B 1 334 ? 131.553 136.036 141.332 1.00 237.12 ?  334  ARG B N   1 
ATOM   5198 C CA  . ARG B 1 334 ? 131.128 134.761 141.881 1.00 237.12 ?  334  ARG B CA  1 
ATOM   5199 C C   . ARG B 1 334 ? 130.248 135.037 143.074 1.00 237.12 ?  334  ARG B C   1 
ATOM   5200 O O   . ARG B 1 334 ? 130.707 135.577 144.078 1.00 237.12 ?  334  ARG B O   1 
ATOM   5201 C CB  . ARG B 1 334 ? 132.328 133.900 142.256 1.00 237.12 ?  334  ARG B CB  1 
ATOM   5202 C CG  . ARG B 1 334 ? 132.655 132.843 141.217 1.00 237.12 ?  334  ARG B CG  1 
ATOM   5203 C CD  . ARG B 1 334 ? 133.377 133.448 140.025 1.00 237.12 ?  334  ARG B CD  1 
ATOM   5204 N NE  . ARG B 1 334 ? 133.093 132.736 138.784 1.00 237.12 ?  334  ARG B NE  1 
ATOM   5205 C CZ  . ARG B 1 334 ? 133.945 132.641 137.769 1.00 237.12 ?  334  ARG B CZ  1 
ATOM   5206 N NH1 . ARG B 1 334 ? 135.139 133.214 137.849 1.00 237.12 1  334  ARG B NH1 1 
ATOM   5207 N NH2 . ARG B 1 334 ? 133.607 131.975 136.673 1.00 237.12 ?  334  ARG B NH2 1 
ATOM   5208 N N   . THR B 1 335 ? 128.976 134.679 142.973 1.00 241.14 ?  335  THR B N   1 
ATOM   5209 C CA  . THR B 1 335 ? 128.045 134.994 144.043 1.00 241.14 ?  335  THR B CA  1 
ATOM   5210 C C   . THR B 1 335 ? 127.908 133.914 145.092 1.00 241.14 ?  335  THR B C   1 
ATOM   5211 O O   . THR B 1 335 ? 128.342 132.783 144.884 1.00 241.14 ?  335  THR B O   1 
ATOM   5212 C CB  . THR B 1 335 ? 126.653 135.254 143.481 1.00 241.14 ?  335  THR B CB  1 
ATOM   5213 O OG1 . THR B 1 335 ? 126.125 134.037 142.943 1.00 241.14 ?  335  THR B OG1 1 
ATOM   5214 C CG2 . THR B 1 335 ? 126.718 136.295 142.404 1.00 241.14 ?  335  THR B CG2 1 
ATOM   5215 N N   . ASN B 1 336 ? 127.293 134.260 146.218 1.00 222.54 ?  336  ASN B N   1 
ATOM   5216 C CA  . ASN B 1 336 ? 127.113 133.302 147.298 1.00 222.54 ?  336  ASN B CA  1 
ATOM   5217 C C   . ASN B 1 336 ? 125.643 133.201 147.647 1.00 222.54 ?  336  ASN B C   1 
ATOM   5218 O O   . ASN B 1 336 ? 125.253 133.437 148.789 1.00 222.54 ?  336  ASN B O   1 
ATOM   5219 C CB  . ASN B 1 336 ? 127.912 133.734 148.526 1.00 222.54 ?  336  ASN B CB  1 
ATOM   5220 C CG  . ASN B 1 336 ? 128.621 135.059 148.324 1.00 222.54 ?  336  ASN B CG  1 
ATOM   5221 O OD1 . ASN B 1 336 ? 129.725 135.108 147.782 1.00 222.54 ?  336  ASN B OD1 1 
ATOM   5222 N ND2 . ASN B 1 336 ? 127.990 136.142 148.761 1.00 222.54 ?  336  ASN B ND2 1 
ATOM   5223 N N   . PHE B 1 337 ? 124.820 132.849 146.667 1.00 245.34 ?  337  PHE B N   1 
ATOM   5224 C CA  . PHE B 1 337 ? 123.384 132.779 146.898 1.00 245.34 ?  337  PHE B CA  1 
ATOM   5225 C C   . PHE B 1 337 ? 122.968 131.411 147.392 1.00 245.34 ?  337  PHE B C   1 
ATOM   5226 O O   . PHE B 1 337 ? 123.153 130.413 146.700 1.00 245.34 ?  337  PHE B O   1 
ATOM   5227 C CB  . PHE B 1 337 ? 122.612 133.111 145.622 1.00 245.34 ?  337  PHE B CB  1 
ATOM   5228 C CG  . PHE B 1 337 ? 122.887 134.481 145.086 1.00 245.34 ?  337  PHE B CG  1 
ATOM   5229 C CD1 . PHE B 1 337 ? 123.218 135.522 145.936 1.00 245.34 ?  337  PHE B CD1 1 
ATOM   5230 C CD2 . PHE B 1 337 ? 122.809 134.729 143.729 1.00 245.34 ?  337  PHE B CD2 1 
ATOM   5231 C CE1 . PHE B 1 337 ? 123.473 136.781 145.442 1.00 245.34 ?  337  PHE B CE1 1 
ATOM   5232 C CE2 . PHE B 1 337 ? 123.061 135.988 143.229 1.00 245.34 ?  337  PHE B CE2 1 
ATOM   5233 C CZ  . PHE B 1 337 ? 123.395 137.015 144.087 1.00 245.34 ?  337  PHE B CZ  1 
ATOM   5234 N N   . ARG B 1 338 ? 122.402 131.358 148.589 1.00 255.26 ?  338  ARG B N   1 
ATOM   5235 C CA  . ARG B 1 338 ? 121.921 130.096 149.121 1.00 255.26 ?  338  ARG B CA  1 
ATOM   5236 C C   . ARG B 1 338 ? 120.457 129.971 148.756 1.00 255.26 ?  338  ARG B C   1 
ATOM   5237 O O   . ARG B 1 338 ? 119.584 130.288 149.563 1.00 255.26 ?  338  ARG B O   1 
ATOM   5238 C CB  . ARG B 1 338 ? 122.103 130.055 150.636 1.00 255.26 ?  338  ARG B CB  1 
ATOM   5239 C CG  . ARG B 1 338 ? 123.301 130.847 151.135 1.00 255.26 ?  338  ARG B CG  1 
ATOM   5240 C CD  . ARG B 1 338 ? 122.874 131.978 152.058 1.00 255.26 ?  338  ARG B CD  1 
ATOM   5241 N NE  . ARG B 1 338 ? 122.868 133.271 151.380 1.00 255.26 ?  338  ARG B NE  1 
ATOM   5242 C CZ  . ARG B 1 338 ? 121.770 133.888 150.957 1.00 255.26 ?  338  ARG B CZ  1 
ATOM   5243 N NH1 . ARG B 1 338 ? 121.859 135.062 150.353 1.00 255.26 1  338  ARG B NH1 1 
ATOM   5244 N NH2 . ARG B 1 338 ? 120.580 133.332 151.138 1.00 255.26 ?  338  ARG B NH2 1 
ATOM   5245 N N   . MET B 1 339 ? 120.179 129.521 147.539 1.00 275.55 ?  339  MET B N   1 
ATOM   5246 C CA  . MET B 1 339 ? 118.799 129.436 147.082 1.00 275.55 ?  339  MET B CA  1 
ATOM   5247 C C   . MET B 1 339 ? 118.243 128.022 147.155 1.00 275.55 ?  339  MET B C   1 
ATOM   5248 O O   . MET B 1 339 ? 118.986 127.051 147.018 1.00 275.55 ?  339  MET B O   1 
ATOM   5249 C CB  . MET B 1 339 ? 118.688 129.976 145.657 1.00 275.55 ?  339  MET B CB  1 
ATOM   5250 C CG  . MET B 1 339 ? 118.527 131.484 145.583 1.00 275.55 ?  339  MET B CG  1 
ATOM   5251 S SD  . MET B 1 339 ? 118.980 132.146 143.970 1.00 275.55 ?  339  MET B SD  1 
ATOM   5252 C CE  . MET B 1 339 ? 119.829 130.740 143.257 1.00 275.55 ?  339  MET B CE  1 
ATOM   5253 N N   . ASP B 1 340 ? 116.937 127.903 147.372 1.00 278.57 ?  340  ASP B N   1 
ATOM   5254 C CA  . ASP B 1 340 ? 116.305 126.588 147.434 1.00 278.57 ?  340  ASP B CA  1 
ATOM   5255 C C   . ASP B 1 340 ? 116.071 126.063 146.030 1.00 278.57 ?  340  ASP B C   1 
ATOM   5256 O O   . ASP B 1 340 ? 115.544 126.781 145.184 1.00 278.57 ?  340  ASP B O   1 
ATOM   5257 C CB  . ASP B 1 340 ? 114.987 126.663 148.203 1.00 278.57 ?  340  ASP B CB  1 
ATOM   5258 C CG  . ASP B 1 340 ? 114.495 125.304 148.650 1.00 278.57 ?  340  ASP B CG  1 
ATOM   5259 O OD1 . ASP B 1 340 ? 115.335 124.402 148.851 1.00 278.57 ?  340  ASP B OD1 1 
ATOM   5260 O OD2 . ASP B 1 340 ? 113.267 125.138 148.798 1.00 278.57 -1 340  ASP B OD2 1 
ATOM   5261 N N   . PHE B 1 341 ? 116.445 124.813 145.780 1.00 303.84 ?  341  PHE B N   1 
ATOM   5262 C CA  . PHE B 1 341 ? 116.326 124.238 144.434 1.00 303.84 ?  341  PHE B CA  1 
ATOM   5263 C C   . PHE B 1 341 ? 114.993 124.404 143.690 1.00 303.84 ?  341  PHE B C   1 
ATOM   5264 O O   . PHE B 1 341 ? 114.991 124.883 142.555 1.00 303.84 ?  341  PHE B O   1 
ATOM   5265 C CB  . PHE B 1 341 ? 116.779 122.764 144.431 1.00 303.84 ?  341  PHE B CB  1 
ATOM   5266 C CG  . PHE B 1 341 ? 116.343 121.991 143.217 1.00 303.84 ?  341  PHE B CG  1 
ATOM   5267 C CD1 . PHE B 1 341 ? 116.923 122.227 141.980 1.00 303.84 ?  341  PHE B CD1 1 
ATOM   5268 C CD2 . PHE B 1 341 ? 115.358 121.020 143.314 1.00 303.84 ?  341  PHE B CD2 1 
ATOM   5269 C CE1 . PHE B 1 341 ? 116.520 121.520 140.864 1.00 303.84 ?  341  PHE B CE1 1 
ATOM   5270 C CE2 . PHE B 1 341 ? 114.951 120.310 142.201 1.00 303.84 ?  341  PHE B CE2 1 
ATOM   5271 C CZ  . PHE B 1 341 ? 115.535 120.559 140.975 1.00 303.84 ?  341  PHE B CZ  1 
ATOM   5272 N N   . PRO B 1 342 ? 113.856 124.014 144.304 1.00 254.20 ?  342  PRO B N   1 
ATOM   5273 C CA  . PRO B 1 342 ? 112.615 124.090 143.516 1.00 254.20 ?  342  PRO B CA  1 
ATOM   5274 C C   . PRO B 1 342 ? 112.326 125.450 142.885 1.00 254.20 ?  342  PRO B C   1 
ATOM   5275 O O   . PRO B 1 342 ? 111.743 125.448 141.803 1.00 254.20 ?  342  PRO B O   1 
ATOM   5276 C CB  . PRO B 1 342 ? 111.532 123.722 144.531 1.00 254.20 ?  342  PRO B CB  1 
ATOM   5277 C CG  . PRO B 1 342 ? 112.233 122.879 145.535 1.00 254.20 ?  342  PRO B CG  1 
ATOM   5278 C CD  . PRO B 1 342 ? 113.602 123.476 145.654 1.00 254.20 ?  342  PRO B CD  1 
ATOM   5279 N N   . PHE B 1 343 ? 112.701 126.554 143.531 1.00 275.51 ?  343  PHE B N   1 
ATOM   5280 C CA  . PHE B 1 343 ? 112.485 127.917 143.004 1.00 275.51 ?  343  PHE B CA  1 
ATOM   5281 C C   . PHE B 1 343 ? 111.032 128.404 143.019 1.00 275.51 ?  343  PHE B C   1 
ATOM   5282 O O   . PHE B 1 343 ? 110.115 127.695 142.606 1.00 275.51 ?  343  PHE B O   1 
ATOM   5283 C CB  . PHE B 1 343 ? 113.220 128.149 141.658 1.00 275.51 ?  343  PHE B CB  1 
ATOM   5284 C CG  . PHE B 1 343 ? 112.346 128.650 140.536 1.00 275.51 ?  343  PHE B CG  1 
ATOM   5285 C CD1 . PHE B 1 343 ? 112.084 130.003 140.385 1.00 275.51 ?  343  PHE B CD1 1 
ATOM   5286 C CD2 . PHE B 1 343 ? 111.831 127.770 139.599 1.00 275.51 ?  343  PHE B CD2 1 
ATOM   5287 C CE1 . PHE B 1 343 ? 111.290 130.459 139.350 1.00 275.51 ?  343  PHE B CE1 1 
ATOM   5288 C CE2 . PHE B 1 343 ? 111.042 128.220 138.560 1.00 275.51 ?  343  PHE B CE2 1 
ATOM   5289 C CZ  . PHE B 1 343 ? 110.772 129.566 138.435 1.00 275.51 ?  343  PHE B CZ  1 
ATOM   5290 N N   . ASP B 1 344 ? 110.825 129.620 143.510 1.00 271.16 ?  344  ASP B N   1 
ATOM   5291 C CA  . ASP B 1 344 ? 109.476 130.164 143.609 1.00 271.16 ?  344  ASP B CA  1 
ATOM   5292 C C   . ASP B 1 344 ? 108.902 130.532 142.261 1.00 271.16 ?  344  ASP B C   1 
ATOM   5293 O O   . ASP B 1 344 ? 109.347 131.490 141.639 1.00 271.16 ?  344  ASP B O   1 
ATOM   5294 C CB  . ASP B 1 344 ? 109.500 131.406 144.493 1.00 271.16 ?  344  ASP B CB  1 
ATOM   5295 C CG  . ASP B 1 344 ? 108.124 131.841 144.931 1.00 271.16 ?  344  ASP B CG  1 
ATOM   5296 O OD1 . ASP B 1 344 ? 107.268 130.969 145.169 1.00 271.16 ?  344  ASP B OD1 1 
ATOM   5297 O OD2 . ASP B 1 344 ? 107.900 133.061 145.040 1.00 271.16 -1 344  ASP B OD2 1 
ATOM   5298 N N   . LEU B 1 345 ? 107.889 129.802 141.814 1.00 247.04 ?  345  LEU B N   1 
ATOM   5299 C CA  . LEU B 1 345 ? 107.242 130.146 140.557 1.00 247.04 ?  345  LEU B CA  1 
ATOM   5300 C C   . LEU B 1 345 ? 106.305 131.322 140.745 1.00 247.04 ?  345  LEU B C   1 
ATOM   5301 O O   . LEU B 1 345 ? 105.748 131.830 139.778 1.00 247.04 ?  345  LEU B O   1 
ATOM   5302 C CB  . LEU B 1 345 ? 106.486 128.954 139.977 1.00 247.04 ?  345  LEU B CB  1 
ATOM   5303 C CG  . LEU B 1 345 ? 107.201 128.157 138.889 1.00 247.04 ?  345  LEU B CG  1 
ATOM   5304 C CD1 . LEU B 1 345 ? 107.583 126.778 139.404 1.00 247.04 ?  345  LEU B CD1 1 
ATOM   5305 C CD2 . LEU B 1 345 ? 106.324 128.047 137.653 1.00 247.04 ?  345  LEU B CD2 1 
ATOM   5306 N N   . LYS B 1 346 ? 106.120 131.759 141.985 1.00 266.65 ?  346  LYS B N   1 
ATOM   5307 C CA  . LYS B 1 346 ? 105.289 132.924 142.238 1.00 266.65 ?  346  LYS B CA  1 
ATOM   5308 C C   . LYS B 1 346 ? 106.087 134.183 141.960 1.00 266.65 ?  346  LYS B C   1 
ATOM   5309 O O   . LYS B 1 346 ? 105.512 135.239 141.711 1.00 266.65 ?  346  LYS B O   1 
ATOM   5310 C CB  . LYS B 1 346 ? 104.774 132.927 143.673 1.00 266.65 ?  346  LYS B CB  1 
ATOM   5311 C CG  . LYS B 1 346 ? 103.747 131.846 143.959 1.00 266.65 ?  346  LYS B CG  1 
ATOM   5312 C CD  . LYS B 1 346 ? 102.820 132.251 145.092 1.00 266.65 ?  346  LYS B CD  1 
ATOM   5313 C CE  . LYS B 1 346 ? 103.098 133.673 145.550 1.00 266.65 ?  346  LYS B CE  1 
ATOM   5314 N NZ  . LYS B 1 346 ? 102.579 133.922 146.923 1.00 266.65 1  346  LYS B NZ  1 
ATOM   5315 N N   . GLU B 1 347 ? 107.412 134.080 141.998 1.00 288.93 ?  347  GLU B N   1 
ATOM   5316 C CA  . GLU B 1 347 ? 108.245 135.231 141.666 1.00 288.93 ?  347  GLU B CA  1 
ATOM   5317 C C   . GLU B 1 347 ? 108.768 135.129 140.247 1.00 288.93 ?  347  GLU B C   1 
ATOM   5318 O O   . GLU B 1 347 ? 109.521 135.987 139.802 1.00 288.93 ?  347  GLU B O   1 
ATOM   5319 C CB  . GLU B 1 347 ? 109.365 135.448 142.689 1.00 288.93 ?  347  GLU B CB  1 
ATOM   5320 C CG  . GLU B 1 347 ? 110.497 134.442 142.676 1.00 288.93 ?  347  GLU B CG  1 
ATOM   5321 C CD  . GLU B 1 347 ? 111.462 134.665 143.825 1.00 288.93 ?  347  GLU B CD  1 
ATOM   5322 O OE1 . GLU B 1 347 ? 111.059 134.469 144.991 1.00 288.93 ?  347  GLU B OE1 1 
ATOM   5323 O OE2 . GLU B 1 347 ? 112.622 135.047 143.566 1.00 288.93 -1 347  GLU B OE2 1 
ATOM   5324 N N   . LEU B 1 348 ? 108.368 134.090 139.525 1.00 269.76 ?  348  LEU B N   1 
ATOM   5325 C CA  . LEU B 1 348 ? 108.741 133.988 138.114 1.00 269.76 ?  348  LEU B CA  1 
ATOM   5326 C C   . LEU B 1 348 ? 108.145 135.125 137.282 1.00 269.76 ?  348  LEU B C   1 
ATOM   5327 O O   . LEU B 1 348 ? 108.807 135.629 136.384 1.00 269.76 ?  348  LEU B O   1 
ATOM   5328 C CB  . LEU B 1 348 ? 108.371 132.621 137.528 1.00 269.76 ?  348  LEU B CB  1 
ATOM   5329 C CG  . LEU B 1 348 ? 108.801 132.334 136.086 1.00 269.76 ?  348  LEU B CG  1 
ATOM   5330 C CD1 . LEU B 1 348 ? 110.312 132.408 135.936 1.00 269.76 ?  348  LEU B CD1 1 
ATOM   5331 C CD2 . LEU B 1 348 ? 108.278 130.984 135.625 1.00 269.76 ?  348  LEU B CD2 1 
ATOM   5332 N N   . PRO B 1 349 ? 106.886 135.530 137.555 1.00 289.85 ?  349  PRO B N   1 
ATOM   5333 C CA  . PRO B 1 349 ? 106.394 136.698 136.815 1.00 289.85 ?  349  PRO B CA  1 
ATOM   5334 C C   . PRO B 1 349 ? 107.327 137.906 136.909 1.00 289.85 ?  349  PRO B C   1 
ATOM   5335 O O   . PRO B 1 349 ? 107.446 138.640 135.936 1.00 289.85 ?  349  PRO B O   1 
ATOM   5336 C CB  . PRO B 1 349 ? 105.078 137.006 137.517 1.00 289.85 ?  349  PRO B CB  1 
ATOM   5337 C CG  . PRO B 1 349 ? 104.567 135.672 137.916 1.00 289.85 ?  349  PRO B CG  1 
ATOM   5338 C CD  . PRO B 1 349 ? 105.764 134.804 138.186 1.00 289.85 ?  349  PRO B CD  1 
ATOM   5339 N N   . ALA B 1 350 ? 107.970 138.112 138.054 1.00 309.05 ?  350  ALA B N   1 
ATOM   5340 C CA  . ALA B 1 350 ? 108.896 139.225 138.216 1.00 309.05 ?  350  ALA B CA  1 
ATOM   5341 C C   . ALA B 1 350 ? 110.115 139.060 137.334 1.00 309.05 ?  350  ALA B C   1 
ATOM   5342 O O   . ALA B 1 350 ? 110.560 140.016 136.714 1.00 309.05 ?  350  ALA B O   1 
ATOM   5343 C CB  . ALA B 1 350 ? 109.312 139.359 139.665 1.00 309.05 ?  350  ALA B CB  1 
ATOM   5344 N N   . PHE B 1 351 ? 110.660 137.853 137.272 1.00 310.03 ?  351  PHE B N   1 
ATOM   5345 C CA  . PHE B 1 351 ? 111.804 137.592 136.407 1.00 310.03 ?  351  PHE B CA  1 
ATOM   5346 C C   . PHE B 1 351 ? 111.428 137.782 134.949 1.00 310.03 ?  351  PHE B C   1 
ATOM   5347 O O   . PHE B 1 351 ? 112.225 138.276 134.159 1.00 310.03 ?  351  PHE B O   1 
ATOM   5348 C CB  . PHE B 1 351 ? 112.327 136.179 136.630 1.00 310.03 ?  351  PHE B CB  1 
ATOM   5349 C CG  . PHE B 1 351 ? 112.972 135.979 137.967 1.00 310.03 ?  351  PHE B CG  1 
ATOM   5350 C CD1 . PHE B 1 351 ? 114.071 136.731 138.338 1.00 310.03 ?  351  PHE B CD1 1 
ATOM   5351 C CD2 . PHE B 1 351 ? 112.481 135.038 138.852 1.00 310.03 ?  351  PHE B CD2 1 
ATOM   5352 C CE1 . PHE B 1 351 ? 114.670 136.546 139.567 1.00 310.03 ?  351  PHE B CE1 1 
ATOM   5353 C CE2 . PHE B 1 351 ? 113.074 134.850 140.083 1.00 310.03 ?  351  PHE B CE2 1 
ATOM   5354 C CZ  . PHE B 1 351 ? 114.170 135.606 140.442 1.00 310.03 ?  351  PHE B CZ  1 
ATOM   5355 N N   . ALA B 1 352 ? 110.212 137.399 134.586 1.00 330.93 ?  352  ALA B N   1 
ATOM   5356 C CA  . ALA B 1 352 ? 109.751 137.581 133.218 1.00 330.93 ?  352  ALA B CA  1 
ATOM   5357 C C   . ALA B 1 352 ? 109.574 139.055 132.919 1.00 330.93 ?  352  ALA B C   1 
ATOM   5358 O O   . ALA B 1 352 ? 109.880 139.501 131.823 1.00 330.93 ?  352  ALA B O   1 
ATOM   5359 C CB  . ALA B 1 352 ? 108.449 136.838 132.998 1.00 330.93 ?  352  ALA B CB  1 
ATOM   5360 N N   . ALA B 1 353 ? 109.082 139.816 133.889 1.00 337.56 ?  353  ALA B N   1 
ATOM   5361 C CA  . ALA B 1 353 ? 108.927 141.254 133.707 1.00 337.56 ?  353  ALA B CA  1 
ATOM   5362 C C   . ALA B 1 353 ? 110.286 141.891 133.530 1.00 337.56 ?  353  ALA B C   1 
ATOM   5363 O O   . ALA B 1 353 ? 110.440 142.788 132.710 1.00 337.56 ?  353  ALA B O   1 
ATOM   5364 C CB  . ALA B 1 353 ? 108.203 141.869 134.887 1.00 337.56 ?  353  ALA B CB  1 
ATOM   5365 N N   . ILE B 1 354 ? 111.278 141.437 134.290 1.00 316.46 ?  354  ILE B N   1 
ATOM   5366 C CA  . ILE B 1 354 ? 112.632 141.939 134.112 1.00 316.46 ?  354  ILE B CA  1 
ATOM   5367 C C   . ILE B 1 354 ? 112.996 141.733 132.659 1.00 316.46 ?  354  ILE B C   1 
ATOM   5368 O O   . ILE B 1 354 ? 113.381 142.672 131.985 1.00 316.46 ?  354  ILE B O   1 
ATOM   5369 C CB  . ILE B 1 354 ? 113.646 141.197 135.000 1.00 316.46 ?  354  ILE B CB  1 
ATOM   5370 C CG1 . ILE B 1 354 ? 113.485 141.600 136.462 1.00 316.46 ?  354  ILE B CG1 1 
ATOM   5371 C CG2 . ILE B 1 354 ? 115.069 141.482 134.555 1.00 316.46 ?  354  ILE B CG2 1 
ATOM   5372 C CD1 . ILE B 1 354 ? 114.518 140.971 137.367 1.00 316.46 ?  354  ILE B CD1 1 
ATOM   5373 N N   . GLY B 1 355 ? 112.840 140.513 132.162 1.00 313.43 ?  355  GLY B N   1 
ATOM   5374 C CA  . GLY B 1 355 ? 113.136 140.223 130.774 1.00 313.43 ?  355  GLY B CA  1 
ATOM   5375 C C   . GLY B 1 355 ? 112.456 141.137 129.782 1.00 313.43 ?  355  GLY B C   1 
ATOM   5376 O O   . GLY B 1 355 ? 113.111 141.713 128.927 1.00 313.43 ?  355  GLY B O   1 
ATOM   5377 N N   . ILE B 1 356 ? 111.143 141.276 129.884 1.00 339.55 ?  356  ILE B N   1 
ATOM   5378 C CA  . ILE B 1 356 ? 110.404 142.117 128.955 1.00 339.55 ?  356  ILE B CA  1 
ATOM   5379 C C   . ILE B 1 356 ? 110.940 143.537 128.972 1.00 339.55 ?  356  ILE B C   1 
ATOM   5380 O O   . ILE B 1 356 ? 111.239 144.106 127.925 1.00 339.55 ?  356  ILE B O   1 
ATOM   5381 C CB  . ILE B 1 356 ? 108.900 142.133 129.284 1.00 339.55 ?  356  ILE B CB  1 
ATOM   5382 C CG1 . ILE B 1 356 ? 108.319 140.725 129.184 1.00 339.55 ?  356  ILE B CG1 1 
ATOM   5383 C CG2 . ILE B 1 356 ? 108.148 143.071 128.352 1.00 339.55 ?  356  ILE B CG2 1 
ATOM   5384 C CD1 . ILE B 1 356 ? 107.712 140.411 127.836 1.00 339.55 ?  356  ILE B CD1 1 
ATOM   5385 N N   . CYS B 1 357 ? 111.081 144.109 130.161 1.00 342.37 ?  357  CYS B N   1 
ATOM   5386 C CA  . CYS B 1 357 ? 111.556 145.480 130.276 1.00 342.37 ?  357  CYS B CA  1 
ATOM   5387 C C   . CYS B 1 357 ? 113.000 145.618 129.842 1.00 342.37 ?  357  CYS B C   1 
ATOM   5388 O O   . CYS B 1 357 ? 113.375 146.634 129.279 1.00 342.37 ?  357  CYS B O   1 
ATOM   5389 C CB  . CYS B 1 357 ? 111.377 145.985 131.701 1.00 342.37 ?  357  CYS B CB  1 
ATOM   5390 S SG  . CYS B 1 357 ? 109.663 146.050 132.264 1.00 342.37 ?  357  CYS B SG  1 
ATOM   5391 N N   . CYS B 1 358 ? 113.812 144.599 130.084 1.00 330.10 ?  358  CYS B N   1 
ATOM   5392 C CA  . CYS B 1 358 ? 115.201 144.625 129.651 1.00 330.10 ?  358  CYS B CA  1 
ATOM   5393 C C   . CYS B 1 358 ? 115.281 144.548 128.141 1.00 330.10 ?  358  CYS B C   1 
ATOM   5394 O O   . CYS B 1 358 ? 116.211 145.074 127.547 1.00 330.10 ?  358  CYS B O   1 
ATOM   5395 C CB  . CYS B 1 358 ? 115.986 143.480 130.278 1.00 330.10 ?  358  CYS B CB  1 
ATOM   5396 S SG  . CYS B 1 358 ? 116.587 143.812 131.948 1.00 330.10 ?  358  CYS B SG  1 
ATOM   5397 N N   . GLY B 1 359 ? 114.310 143.899 127.512 1.00 335.59 ?  359  GLY B N   1 
ATOM   5398 C CA  . GLY B 1 359 ? 114.275 143.839 126.064 1.00 335.59 ?  359  GLY B CA  1 
ATOM   5399 C C   . GLY B 1 359 ? 113.935 145.196 125.507 1.00 335.59 ?  359  GLY B C   1 
ATOM   5400 O O   . GLY B 1 359 ? 114.514 145.628 124.516 1.00 335.59 ?  359  GLY B O   1 
ATOM   5401 N N   . LEU B 1 360 ? 113.001 145.883 126.149 1.00 355.91 ?  360  LEU B N   1 
ATOM   5402 C CA  . LEU B 1 360 ? 112.639 147.221 125.717 1.00 355.91 ?  360  LEU B CA  1 
ATOM   5403 C C   . LEU B 1 360 ? 113.813 148.155 125.907 1.00 355.91 ?  360  LEU B C   1 
ATOM   5404 O O   . LEU B 1 360 ? 114.122 148.948 125.028 1.00 355.91 ?  360  LEU B O   1 
ATOM   5405 C CB  . LEU B 1 360 ? 111.443 147.734 126.515 1.00 355.91 ?  360  LEU B CB  1 
ATOM   5406 C CG  . LEU B 1 360 ? 110.086 147.077 126.273 1.00 355.91 ?  360  LEU B CG  1 
ATOM   5407 C CD1 . LEU B 1 360 ? 109.256 147.094 127.546 1.00 355.91 ?  360  LEU B CD1 1 
ATOM   5408 C CD2 . LEU B 1 360 ? 109.352 147.789 125.150 1.00 355.91 ?  360  LEU B CD2 1 
ATOM   5409 N N   . LEU B 1 361 ? 114.481 148.056 127.050 1.00 288.30 ?  361  LEU B N   1 
ATOM   5410 C CA  . LEU B 1 361 ? 115.610 148.931 127.339 1.00 288.30 ?  361  LEU B CA  1 
ATOM   5411 C C   . LEU B 1 361 ? 116.812 148.587 126.486 1.00 288.30 ?  361  LEU B C   1 
ATOM   5412 O O   . LEU B 1 361 ? 117.620 149.452 126.181 1.00 288.30 ?  361  LEU B O   1 
ATOM   5413 C CB  . LEU B 1 361 ? 115.970 148.862 128.820 1.00 288.30 ?  361  LEU B CB  1 
ATOM   5414 C CG  . LEU B 1 361 ? 114.966 149.531 129.754 1.00 288.30 ?  361  LEU B CG  1 
ATOM   5415 C CD1 . LEU B 1 361 ? 115.050 148.940 131.152 1.00 288.30 ?  361  LEU B CD1 1 
ATOM   5416 C CD2 . LEU B 1 361 ? 115.170 151.036 129.776 1.00 288.30 ?  361  LEU B CD2 1 
ATOM   5417 N N   . GLY B 1 362 ? 116.935 147.329 126.091 1.00 272.11 ?  362  GLY B N   1 
ATOM   5418 C CA  . GLY B 1 362 ? 118.025 146.928 125.228 1.00 272.11 ?  362  GLY B CA  1 
ATOM   5419 C C   . GLY B 1 362 ? 117.833 147.547 123.873 1.00 272.11 ?  362  GLY B C   1 
ATOM   5420 O O   . GLY B 1 362 ? 118.787 148.001 123.256 1.00 272.11 ?  362  GLY B O   1 
ATOM   5421 N N   . ALA B 1 363 ? 116.593 147.585 123.407 1.00 285.87 ?  363  ALA B N   1 
ATOM   5422 C CA  . ALA B 1 363 ? 116.304 148.209 122.131 1.00 285.87 ?  363  ALA B CA  1 
ATOM   5423 C C   . ALA B 1 363 ? 116.547 149.702 122.209 1.00 285.87 ?  363  ALA B C   1 
ATOM   5424 O O   . ALA B 1 363 ? 117.078 150.285 121.276 1.00 285.87 ?  363  ALA B O   1 
ATOM   5425 C CB  . ALA B 1 363 ? 114.879 147.923 121.719 1.00 285.87 ?  363  ALA B CB  1 
ATOM   5426 N N   . VAL B 1 364 ? 116.176 150.327 123.319 1.00 252.87 ?  364  VAL B N   1 
ATOM   5427 C CA  . VAL B 1 364 ? 116.434 151.753 123.494 1.00 252.87 ?  364  VAL B CA  1 
ATOM   5428 C C   . VAL B 1 364 ? 117.932 152.014 123.471 1.00 252.87 ?  364  VAL B C   1 
ATOM   5429 O O   . VAL B 1 364 ? 118.384 152.954 122.832 1.00 252.87 ?  364  VAL B O   1 
ATOM   5430 C CB  . VAL B 1 364 ? 115.806 152.290 124.795 1.00 252.87 ?  364  VAL B CB  1 
ATOM   5431 C CG1 . VAL B 1 364 ? 116.245 153.718 125.067 1.00 252.87 ?  364  VAL B CG1 1 
ATOM   5432 C CG2 . VAL B 1 364 ? 114.291 152.222 124.714 1.00 252.87 ?  364  VAL B CG2 1 
ATOM   5433 N N   . PHE B 1 365 ? 118.711 151.174 124.143 1.00 248.26 ?  365  PHE B N   1 
ATOM   5434 C CA  . PHE B 1 365 ? 120.159 151.320 124.125 1.00 248.26 ?  365  PHE B CA  1 
ATOM   5435 C C   . PHE B 1 365 ? 120.657 151.293 122.696 1.00 248.26 ?  365  PHE B C   1 
ATOM   5436 O O   . PHE B 1 365 ? 121.328 152.217 122.261 1.00 248.26 ?  365  PHE B O   1 
ATOM   5437 C CB  . PHE B 1 365 ? 120.824 150.203 124.929 1.00 248.26 ?  365  PHE B CB  1 
ATOM   5438 C CG  . PHE B 1 365 ? 122.271 150.455 125.249 1.00 248.26 ?  365  PHE B CG  1 
ATOM   5439 C CD1 . PHE B 1 365 ? 123.268 150.117 124.348 1.00 248.26 ?  365  PHE B CD1 1 
ATOM   5440 C CD2 . PHE B 1 365 ? 122.634 151.017 126.459 1.00 248.26 ?  365  PHE B CD2 1 
ATOM   5441 C CE1 . PHE B 1 365 ? 124.597 150.348 124.641 1.00 248.26 ?  365  PHE B CE1 1 
ATOM   5442 C CE2 . PHE B 1 365 ? 123.961 151.248 126.759 1.00 248.26 ?  365  PHE B CE2 1 
ATOM   5443 C CZ  . PHE B 1 365 ? 124.944 150.913 125.850 1.00 248.26 ?  365  PHE B CZ  1 
ATOM   5444 N N   . VAL B 1 366 ? 120.332 150.235 121.963 1.00 255.93 ?  366  VAL B N   1 
ATOM   5445 C CA  . VAL B 1 366 ? 120.797 150.109 120.589 1.00 255.93 ?  366  VAL B CA  1 
ATOM   5446 C C   . VAL B 1 366 ? 120.358 151.306 119.763 1.00 255.93 ?  366  VAL B C   1 
ATOM   5447 O O   . VAL B 1 366 ? 121.171 151.914 119.073 1.00 255.93 ?  366  VAL B O   1 
ATOM   5448 C CB  . VAL B 1 366 ? 120.312 148.805 119.934 1.00 255.93 ?  366  VAL B CB  1 
ATOM   5449 C CG1 . VAL B 1 366 ? 120.770 148.738 118.490 1.00 255.93 ?  366  VAL B CG1 1 
ATOM   5450 C CG2 . VAL B 1 366 ? 120.832 147.603 120.703 1.00 255.93 ?  366  VAL B CG2 1 
ATOM   5451 N N   . TYR B 1 367 ? 119.084 151.664 119.849 1.00 277.07 ?  367  TYR B N   1 
ATOM   5452 C CA  . TYR B 1 367 ? 118.576 152.804 119.103 1.00 277.07 ?  367  TYR B CA  1 
ATOM   5453 C C   . TYR B 1 367 ? 119.344 154.066 119.416 1.00 277.07 ?  367  TYR B C   1 
ATOM   5454 O O   . TYR B 1 367 ? 119.852 154.718 118.516 1.00 277.07 ?  367  TYR B O   1 
ATOM   5455 C CB  . TYR B 1 367 ? 117.102 153.027 119.415 1.00 277.07 ?  367  TYR B CB  1 
ATOM   5456 C CG  . TYR B 1 367 ? 116.463 154.121 118.597 1.00 277.07 ?  367  TYR B CG  1 
ATOM   5457 C CD1 . TYR B 1 367 ? 116.140 153.916 117.265 1.00 277.07 ?  367  TYR B CD1 1 
ATOM   5458 C CD2 . TYR B 1 367 ? 116.181 155.358 119.156 1.00 277.07 ?  367  TYR B CD2 1 
ATOM   5459 C CE1 . TYR B 1 367 ? 115.555 154.912 116.512 1.00 277.07 ?  367  TYR B CE1 1 
ATOM   5460 C CE2 . TYR B 1 367 ? 115.599 156.362 118.411 1.00 277.07 ?  367  TYR B CE2 1 
ATOM   5461 C CZ  . TYR B 1 367 ? 115.288 156.133 117.089 1.00 277.07 ?  367  TYR B CZ  1 
ATOM   5462 O OH  . TYR B 1 367 ? 114.706 157.130 116.342 1.00 277.07 ?  367  TYR B OH  1 
ATOM   5463 N N   . LEU B 1 368 ? 119.433 154.419 120.689 1.00 258.19 ?  368  LEU B N   1 
ATOM   5464 C CA  . LEU B 1 368 ? 120.096 155.655 121.077 1.00 258.19 ?  368  LEU B CA  1 
ATOM   5465 C C   . LEU B 1 368 ? 121.573 155.658 120.734 1.00 258.19 ?  368  LEU B C   1 
ATOM   5466 O O   . LEU B 1 368 ? 122.114 156.685 120.344 1.00 258.19 ?  368  LEU B O   1 
ATOM   5467 C CB  . LEU B 1 368 ? 119.901 155.910 122.566 1.00 258.19 ?  368  LEU B CB  1 
ATOM   5468 C CG  . LEU B 1 368 ? 119.012 157.086 122.963 1.00 258.19 ?  368  LEU B CG  1 
ATOM   5469 C CD1 . LEU B 1 368 ? 117.957 157.362 121.904 1.00 258.19 ?  368  LEU B CD1 1 
ATOM   5470 C CD2 . LEU B 1 368 ? 118.366 156.825 124.313 1.00 258.19 ?  368  LEU B CD2 1 
ATOM   5471 N N   . HIS B 1 369 ? 122.230 154.516 120.874 1.00 221.21 ?  369  HIS B N   1 
ATOM   5472 C CA  . HIS B 1 369 ? 123.635 154.427 120.522 1.00 221.21 ?  369  HIS B CA  1 
ATOM   5473 C C   . HIS B 1 369 ? 123.809 154.638 119.033 1.00 221.21 ?  369  HIS B C   1 
ATOM   5474 O O   . HIS B 1 369 ? 124.696 155.366 118.615 1.00 221.21 ?  369  HIS B O   1 
ATOM   5475 C CB  . HIS B 1 369 ? 124.224 153.083 120.938 1.00 221.21 ?  369  HIS B CB  1 
ATOM   5476 C CG  . HIS B 1 369 ? 125.610 152.851 120.428 1.00 221.21 ?  369  HIS B CG  1 
ATOM   5477 N ND1 . HIS B 1 369 ? 126.686 153.613 120.827 1.00 221.21 ?  369  HIS B ND1 1 
ATOM   5478 C CD2 . HIS B 1 369 ? 126.095 151.949 119.543 1.00 221.21 ?  369  HIS B CD2 1 
ATOM   5479 C CE1 . HIS B 1 369 ? 127.774 153.188 120.212 1.00 221.21 ?  369  HIS B CE1 1 
ATOM   5480 N NE2 . HIS B 1 369 ? 127.444 152.178 119.429 1.00 221.21 ?  369  HIS B NE2 1 
ATOM   5481 N N   . ARG B 1 370 ? 122.961 154.013 118.225 1.00 225.90 ?  370  ARG B N   1 
ATOM   5482 C CA  . ARG B 1 370 ? 123.030 154.195 116.780 1.00 225.90 ?  370  ARG B CA  1 
ATOM   5483 C C   . ARG B 1 370 ? 122.738 155.633 116.419 1.00 225.90 ?  370  ARG B C   1 
ATOM   5484 O O   . ARG B 1 370 ? 123.377 156.197 115.545 1.00 225.90 ?  370  ARG B O   1 
ATOM   5485 C CB  . ARG B 1 370 ? 122.039 153.273 116.079 1.00 225.90 ?  370  ARG B CB  1 
ATOM   5486 C CG  . ARG B 1 370 ? 121.974 153.436 114.570 1.00 225.90 ?  370  ARG B CG  1 
ATOM   5487 C CD  . ARG B 1 370 ? 120.901 152.550 113.966 1.00 225.90 ?  370  ARG B CD  1 
ATOM   5488 N NE  . ARG B 1 370 ? 120.416 151.565 114.924 1.00 225.90 ?  370  ARG B NE  1 
ATOM   5489 C CZ  . ARG B 1 370 ? 119.160 151.490 115.348 1.00 225.90 ?  370  ARG B CZ  1 
ATOM   5490 N NH1 . ARG B 1 370 ? 118.255 152.348 114.901 1.00 225.90 1  370  ARG B NH1 1 
ATOM   5491 N NH2 . ARG B 1 370 ? 118.814 150.561 116.224 1.00 225.90 ?  370  ARG B NH2 1 
ATOM   5492 N N   . GLN B 1 371 ? 121.782 156.239 117.105 1.00 244.03 ?  371  GLN B N   1 
ATOM   5493 C CA  . GLN B 1 371 ? 121.415 157.615 116.819 1.00 244.03 ?  371  GLN B CA  1 
ATOM   5494 C C   . GLN B 1 371 ? 122.558 158.567 117.124 1.00 244.03 ?  371  GLN B C   1 
ATOM   5495 O O   . GLN B 1 371 ? 122.808 159.494 116.365 1.00 244.03 ?  371  GLN B O   1 
ATOM   5496 C CB  . GLN B 1 371 ? 120.163 158.003 117.606 1.00 244.03 ?  371  GLN B CB  1 
ATOM   5497 C CG  . GLN B 1 371 ? 118.885 158.073 116.782 1.00 244.03 ?  371  GLN B CG  1 
ATOM   5498 C CD  . GLN B 1 371 ? 118.814 157.024 115.687 1.00 244.03 ?  371  GLN B CD  1 
ATOM   5499 O OE1 . GLN B 1 371 ? 118.763 155.825 115.959 1.00 244.03 ?  371  GLN B OE1 1 
ATOM   5500 N NE2 . GLN B 1 371 ? 118.796 157.474 114.439 1.00 244.03 ?  371  GLN B NE2 1 
ATOM   5501 N N   . VAL B 1 372 ? 123.256 158.341 118.229 1.00 207.35 ?  372  VAL B N   1 
ATOM   5502 C CA  . VAL B 1 372 ? 124.396 159.180 118.584 1.00 207.35 ?  372  VAL B CA  1 
ATOM   5503 C C   . VAL B 1 372 ? 125.542 158.880 117.639 1.00 207.35 ?  372  VAL B C   1 
ATOM   5504 O O   . VAL B 1 372 ? 126.250 159.787 117.211 1.00 207.35 ?  372  VAL B O   1 
ATOM   5505 C CB  . VAL B 1 372 ? 124.834 158.936 120.044 1.00 207.35 ?  372  VAL B CB  1 
ATOM   5506 C CG1 . VAL B 1 372 ? 126.154 159.624 120.350 1.00 207.35 ?  372  VAL B CG1 1 
ATOM   5507 C CG2 . VAL B 1 372 ? 123.763 159.426 121.005 1.00 207.35 ?  372  VAL B CG2 1 
ATOM   5508 N N   . MET B 1 373 ? 125.703 157.616 117.268 1.00 218.54 ?  373  MET B N   1 
ATOM   5509 C CA  . MET B 1 373 ? 126.826 157.228 116.429 1.00 218.54 ?  373  MET B CA  1 
ATOM   5510 C C   . MET B 1 373 ? 126.652 157.869 115.075 1.00 218.54 ?  373  MET B C   1 
ATOM   5511 O O   . MET B 1 373 ? 127.601 158.386 114.510 1.00 218.54 ?  373  MET B O   1 
ATOM   5512 C CB  . MET B 1 373 ? 126.902 155.711 116.281 1.00 218.54 ?  373  MET B CB  1 
ATOM   5513 C CG  . MET B 1 373 ? 128.246 155.113 116.649 1.00 218.54 ?  373  MET B CG  1 
ATOM   5514 S SD  . MET B 1 373 ? 128.361 153.367 116.219 1.00 218.54 ?  373  MET B SD  1 
ATOM   5515 C CE  . MET B 1 373 ? 130.016 152.989 116.788 1.00 218.54 ?  373  MET B CE  1 
ATOM   5516 N N   . LEU B 1 374 ? 125.433 157.840 114.551 1.00 247.46 ?  374  LEU B N   1 
ATOM   5517 C CA  . LEU B 1 374 ? 125.164 158.463 113.269 1.00 247.46 ?  374  LEU B CA  1 
ATOM   5518 C C   . LEU B 1 374 ? 125.273 159.957 113.431 1.00 247.46 ?  374  LEU B C   1 
ATOM   5519 O O   . LEU B 1 374 ? 126.000 160.602 112.693 1.00 247.46 ?  374  LEU B O   1 
ATOM   5520 C CB  . LEU B 1 374 ? 123.772 158.095 112.770 1.00 247.46 ?  374  LEU B CB  1 
ATOM   5521 C CG  . LEU B 1 374 ? 123.608 156.697 112.177 1.00 247.46 ?  374  LEU B CG  1 
ATOM   5522 C CD1 . LEU B 1 374 ? 122.135 156.385 111.969 1.00 247.46 ?  374  LEU B CD1 1 
ATOM   5523 C CD2 . LEU B 1 374 ? 124.377 156.574 110.873 1.00 247.46 ?  374  LEU B CD2 1 
ATOM   5524 N N   . GLY B 1 375 ? 124.572 160.509 114.410 1.00 229.17 ?  375  GLY B N   1 
ATOM   5525 C CA  . GLY B 1 375 ? 124.590 161.942 114.641 1.00 229.17 ?  375  GLY B CA  1 
ATOM   5526 C C   . GLY B 1 375 ? 125.939 162.623 114.581 1.00 229.17 ?  375  GLY B C   1 
ATOM   5527 O O   . GLY B 1 375 ? 126.080 163.643 113.913 1.00 229.17 ?  375  GLY B O   1 
ATOM   5528 N N   . VAL B 1 376 ? 126.937 162.075 115.266 1.00 228.87 ?  376  VAL B N   1 
ATOM   5529 C CA  . VAL B 1 376 ? 128.243 162.731 115.314 1.00 228.87 ?  376  VAL B CA  1 
ATOM   5530 C C   . VAL B 1 376 ? 128.932 162.822 113.954 1.00 228.87 ?  376  VAL B C   1 
ATOM   5531 O O   . VAL B 1 376 ? 129.759 163.707 113.745 1.00 228.87 ?  376  VAL B O   1 
ATOM   5532 C CB  . VAL B 1 376 ? 129.190 162.104 116.362 1.00 228.87 ?  376  VAL B CB  1 
ATOM   5533 C CG1 . VAL B 1 376 ? 128.640 162.310 117.763 1.00 228.87 ?  376  VAL B CG1 1 
ATOM   5534 C CG2 . VAL B 1 376 ? 129.434 160.633 116.079 1.00 228.87 ?  376  VAL B CG2 1 
ATOM   5535 N N   . ARG B 1 377 ? 128.598 161.928 113.027 1.00 232.24 ?  377  ARG B N   1 
ATOM   5536 C CA  . ARG B 1 377 ? 129.172 162.014 111.685 1.00 232.24 ?  377  ARG B CA  1 
ATOM   5537 C C   . ARG B 1 377 ? 128.194 162.569 110.651 1.00 232.24 ?  377  ARG B C   1 
ATOM   5538 O O   . ARG B 1 377 ? 128.594 163.303 109.750 1.00 232.24 ?  377  ARG B O   1 
ATOM   5539 C CB  . ARG B 1 377 ? 129.720 160.664 111.217 1.00 232.24 ?  377  ARG B CB  1 
ATOM   5540 C CG  . ARG B 1 377 ? 129.450 159.503 112.152 1.00 232.24 ?  377  ARG B CG  1 
ATOM   5541 C CD  . ARG B 1 377 ? 128.842 158.333 111.398 1.00 232.24 ?  377  ARG B CD  1 
ATOM   5542 N NE  . ARG B 1 377 ? 127.816 158.772 110.459 1.00 232.24 ?  377  ARG B NE  1 
ATOM   5543 C CZ  . ARG B 1 377 ? 127.467 158.101 109.368 1.00 232.24 ?  377  ARG B CZ  1 
ATOM   5544 N NH1 . ARG B 1 377 ? 126.524 158.578 108.568 1.00 232.24 1  377  ARG B NH1 1 
ATOM   5545 N NH2 . ARG B 1 377 ? 128.059 156.951 109.077 1.00 232.24 ?  377  ARG B NH2 1 
ATOM   5546 N N   . LYS B 1 378 ? 126.917 162.227 110.774 1.00 222.40 ?  378  LYS B N   1 
ATOM   5547 C CA  . LYS B 1 378 ? 125.936 162.681 109.795 1.00 222.40 ?  378  LYS B CA  1 
ATOM   5548 C C   . LYS B 1 378 ? 125.752 164.190 109.845 1.00 222.40 ?  378  LYS B C   1 
ATOM   5549 O O   . LYS B 1 378 ? 125.447 164.808 108.826 1.00 222.40 ?  378  LYS B O   1 
ATOM   5550 C CB  . LYS B 1 378 ? 124.598 161.938 109.940 1.00 222.40 ?  378  LYS B CB  1 
ATOM   5551 C CG  . LYS B 1 378 ? 123.680 162.450 111.038 1.00 222.40 ?  378  LYS B CG  1 
ATOM   5552 C CD  . LYS B 1 378 ? 122.363 162.959 110.478 1.00 222.40 ?  378  LYS B CD  1 
ATOM   5553 C CE  . LYS B 1 378 ? 121.961 164.265 111.141 1.00 222.40 ?  378  LYS B CE  1 
ATOM   5554 N NZ  . LYS B 1 378 ? 122.686 164.475 112.424 1.00 222.40 1  378  LYS B NZ  1 
ATOM   5555 N N   . HIS B 1 379 ? 125.937 164.793 111.013 1.00 220.23 ?  379  HIS B N   1 
ATOM   5556 C CA  . HIS B 1 379 ? 125.867 166.243 111.091 1.00 220.23 ?  379  HIS B CA  1 
ATOM   5557 C C   . HIS B 1 379 ? 127.174 166.769 110.530 1.00 220.23 ?  379  HIS B C   1 
ATOM   5558 O O   . HIS B 1 379 ? 128.230 166.561 111.121 1.00 220.23 ?  379  HIS B O   1 
ATOM   5559 C CB  . HIS B 1 379 ? 125.662 166.708 112.529 1.00 220.23 ?  379  HIS B CB  1 
ATOM   5560 C CG  . HIS B 1 379 ? 125.544 168.193 112.672 1.00 220.23 ?  379  HIS B CG  1 
ATOM   5561 N ND1 . HIS B 1 379 ? 125.909 168.860 113.822 1.00 220.23 ?  379  HIS B ND1 1 
ATOM   5562 C CD2 . HIS B 1 379 ? 125.100 169.140 111.813 1.00 220.23 ?  379  HIS B CD2 1 
ATOM   5563 C CE1 . HIS B 1 379 ? 125.697 170.154 113.664 1.00 220.23 ?  379  HIS B CE1 1 
ATOM   5564 N NE2 . HIS B 1 379 ? 125.206 170.351 112.454 1.00 220.23 ?  379  HIS B NE2 1 
ATOM   5565 N N   . LYS B 1 380 ? 127.113 167.438 109.384 1.00 238.70 ?  380  LYS B N   1 
ATOM   5566 C CA  . LYS B 1 380 ? 128.328 167.923 108.737 1.00 238.70 ?  380  LYS B CA  1 
ATOM   5567 C C   . LYS B 1 380 ? 129.209 168.757 109.655 1.00 238.70 ?  380  LYS B C   1 
ATOM   5568 O O   . LYS B 1 380 ? 130.394 168.470 109.807 1.00 238.70 ?  380  LYS B O   1 
ATOM   5569 C CB  . LYS B 1 380 ? 127.983 168.715 107.475 1.00 238.70 ?  380  LYS B CB  1 
ATOM   5570 C CG  . LYS B 1 380 ? 129.028 168.609 106.375 1.00 238.70 ?  380  LYS B CG  1 
ATOM   5571 C CD  . LYS B 1 380 ? 129.736 167.262 106.403 1.00 238.70 ?  380  LYS B CD  1 
ATOM   5572 C CE  . LYS B 1 380 ? 131.242 167.426 106.273 1.00 238.70 ?  380  LYS B CE  1 
ATOM   5573 N NZ  . LYS B 1 380 ? 131.950 167.102 107.542 1.00 238.70 1  380  LYS B NZ  1 
ATOM   5574 N N   . ALA B 1 381 ? 128.639 169.791 110.262 1.00 240.43 ?  381  ALA B N   1 
ATOM   5575 C CA  . ALA B 1 381 ? 129.411 170.648 111.153 1.00 240.43 ?  381  ALA B CA  1 
ATOM   5576 C C   . ALA B 1 381 ? 130.104 169.831 112.231 1.00 240.43 ?  381  ALA B C   1 
ATOM   5577 O O   . ALA B 1 381 ? 131.302 169.988 112.455 1.00 240.43 ?  381  ALA B O   1 
ATOM   5578 C CB  . ALA B 1 381 ? 128.518 171.705 111.779 1.00 240.43 ?  381  ALA B CB  1 
ATOM   5579 N N   . LEU B 1 382 ? 129.357 168.954 112.894 1.00 228.50 ?  382  LEU B N   1 
ATOM   5580 C CA  . LEU B 1 382 ? 129.931 168.126 113.946 1.00 228.50 ?  382  LEU B CA  1 
ATOM   5581 C C   . LEU B 1 382 ? 131.127 167.340 113.444 1.00 228.50 ?  382  LEU B C   1 
ATOM   5582 O O   . LEU B 1 382 ? 132.209 167.436 114.010 1.00 228.50 ?  382  LEU B O   1 
ATOM   5583 C CB  . LEU B 1 382 ? 128.887 167.165 114.506 1.00 228.50 ?  382  LEU B CB  1 
ATOM   5584 C CG  . LEU B 1 382 ? 128.846 167.019 116.024 1.00 228.50 ?  382  LEU B CG  1 
ATOM   5585 C CD1 . LEU B 1 382 ? 129.133 168.356 116.690 1.00 228.50 ?  382  LEU B CD1 1 
ATOM   5586 C CD2 . LEU B 1 382 ? 127.499 166.471 116.468 1.00 228.50 ?  382  LEU B CD2 1 
ATOM   5587 N N   . SER B 1 383 ? 130.938 166.565 112.383 1.00 247.68 ?  383  SER B N   1 
ATOM   5588 C CA  . SER B 1 383 ? 132.025 165.738 111.869 1.00 247.68 ?  383  SER B CA  1 
ATOM   5589 C C   . SER B 1 383 ? 133.247 166.566 111.509 1.00 247.68 ?  383  SER B C   1 
ATOM   5590 O O   . SER B 1 383 ? 134.361 166.201 111.862 1.00 247.68 ?  383  SER B O   1 
ATOM   5591 C CB  . SER B 1 383 ? 131.570 164.914 110.664 1.00 247.68 ?  383  SER B CB  1 
ATOM   5592 O OG  . SER B 1 383 ? 130.592 165.600 109.909 1.00 247.68 ?  383  SER B OG  1 
ATOM   5593 N N   . GLN B 1 384 ? 133.043 167.680 110.814 1.00 260.88 ?  384  GLN B N   1 
ATOM   5594 C CA  . GLN B 1 384 ? 134.153 168.546 110.431 1.00 260.88 ?  384  GLN B CA  1 
ATOM   5595 C C   . GLN B 1 384 ? 134.918 169.027 111.654 1.00 260.88 ?  384  GLN B C   1 
ATOM   5596 O O   . GLN B 1 384 ? 136.142 168.903 111.717 1.00 260.88 ?  384  GLN B O   1 
ATOM   5597 C CB  . GLN B 1 384 ? 133.631 169.739 109.627 1.00 260.88 ?  384  GLN B CB  1 
ATOM   5598 C CG  . GLN B 1 384 ? 134.606 170.897 109.491 1.00 260.88 ?  384  GLN B CG  1 
ATOM   5599 C CD  . GLN B 1 384 ? 134.112 172.157 110.177 1.00 260.88 ?  384  GLN B CD  1 
ATOM   5600 O OE1 . GLN B 1 384 ? 134.800 173.177 110.195 1.00 260.88 ?  384  GLN B OE1 1 
ATOM   5601 N NE2 . GLN B 1 384 ? 132.914 172.090 110.746 1.00 260.88 ?  384  GLN B NE2 1 
ATOM   5602 N N   . PHE B 1 385 ? 134.201 169.564 112.634 1.00 248.33 ?  385  PHE B N   1 
ATOM   5603 C CA  . PHE B 1 385 ? 134.837 170.048 113.851 1.00 248.33 ?  385  PHE B CA  1 
ATOM   5604 C C   . PHE B 1 385 ? 135.590 168.930 114.548 1.00 248.33 ?  385  PHE B C   1 
ATOM   5605 O O   . PHE B 1 385 ? 136.730 169.110 114.965 1.00 248.33 ?  385  PHE B O   1 
ATOM   5606 C CB  . PHE B 1 385 ? 133.777 170.620 114.789 1.00 248.33 ?  385  PHE B CB  1 
ATOM   5607 C CG  . PHE B 1 385 ? 134.335 171.430 115.921 1.00 248.33 ?  385  PHE B CG  1 
ATOM   5608 C CD1 . PHE B 1 385 ? 134.797 172.716 115.706 1.00 248.33 ?  385  PHE B CD1 1 
ATOM   5609 C CD2 . PHE B 1 385 ? 134.385 170.910 117.203 1.00 248.33 ?  385  PHE B CD2 1 
ATOM   5610 C CE1 . PHE B 1 385 ? 135.305 173.468 116.746 1.00 248.33 ?  385  PHE B CE1 1 
ATOM   5611 C CE2 . PHE B 1 385 ? 134.894 171.655 118.249 1.00 248.33 ?  385  PHE B CE2 1 
ATOM   5612 C CZ  . PHE B 1 385 ? 135.354 172.937 118.021 1.00 248.33 ?  385  PHE B CZ  1 
ATOM   5613 N N   . LEU B 1 386 ? 134.964 167.766 114.662 1.00 263.65 ?  386  LEU B N   1 
ATOM   5614 C CA  . LEU B 1 386 ? 135.586 166.652 115.368 1.00 263.65 ?  386  LEU B CA  1 
ATOM   5615 C C   . LEU B 1 386 ? 136.731 166.019 114.587 1.00 263.65 ?  386  LEU B C   1 
ATOM   5616 O O   . LEU B 1 386 ? 137.526 165.275 115.150 1.00 263.65 ?  386  LEU B O   1 
ATOM   5617 C CB  . LEU B 1 386 ? 134.539 165.590 115.709 1.00 263.65 ?  386  LEU B CB  1 
ATOM   5618 C CG  . LEU B 1 386 ? 133.901 165.630 117.100 1.00 263.65 ?  386  LEU B CG  1 
ATOM   5619 C CD1 . LEU B 1 386 ? 134.217 166.921 117.839 1.00 263.65 ?  386  LEU B CD1 1 
ATOM   5620 C CD2 . LEU B 1 386 ? 132.399 165.410 117.009 1.00 263.65 ?  386  LEU B CD2 1 
ATOM   5621 N N   . ALA B 1 387 ? 136.814 166.293 113.292 1.00 306.87 ?  387  ALA B N   1 
ATOM   5622 C CA  . ALA B 1 387 ? 137.921 165.773 112.502 1.00 306.87 ?  387  ALA B CA  1 
ATOM   5623 C C   . ALA B 1 387 ? 139.122 166.673 112.704 1.00 306.87 ?  387  ALA B C   1 
ATOM   5624 O O   . ALA B 1 387 ? 140.257 166.202 112.740 1.00 306.87 ?  387  ALA B O   1 
ATOM   5625 C CB  . ALA B 1 387 ? 137.547 165.698 111.033 1.00 306.87 ?  387  ALA B CB  1 
ATOM   5626 N N   . LYS B 1 388 ? 138.878 167.972 112.840 1.00 268.22 ?  388  LYS B N   1 
ATOM   5627 C CA  . LYS B 1 388 ? 139.968 168.901 113.101 1.00 268.22 ?  388  LYS B CA  1 
ATOM   5628 C C   . LYS B 1 388 ? 140.481 168.673 114.506 1.00 268.22 ?  388  LYS B C   1 
ATOM   5629 O O   . LYS B 1 388 ? 141.684 168.726 114.749 1.00 268.22 ?  388  LYS B O   1 
ATOM   5630 C CB  . LYS B 1 388 ? 139.491 170.342 112.946 1.00 268.22 ?  388  LYS B CB  1 
ATOM   5631 C CG  . LYS B 1 388 ? 139.247 170.756 111.505 1.00 268.22 ?  388  LYS B CG  1 
ATOM   5632 C CD  . LYS B 1 388 ? 138.153 171.805 111.405 1.00 268.22 ?  388  LYS B CD  1 
ATOM   5633 C CE  . LYS B 1 388 ? 137.792 172.357 112.773 1.00 268.22 ?  388  LYS B CE  1 
ATOM   5634 N NZ  . LYS B 1 388 ? 136.551 173.177 112.728 1.00 268.22 1  388  LYS B NZ  1 
ATOM   5635 N N   . HIS B 1 389 ? 139.570 168.418 115.436 1.00 274.50 ?  389  HIS B N   1 
ATOM   5636 C CA  . HIS B 1 389 ? 139.964 168.154 116.811 1.00 274.50 ?  389  HIS B CA  1 
ATOM   5637 C C   . HIS B 1 389 ? 139.531 166.754 117.188 1.00 274.50 ?  389  HIS B C   1 
ATOM   5638 O O   . HIS B 1 389 ? 138.455 166.564 117.746 1.00 274.50 ?  389  HIS B O   1 
ATOM   5639 C CB  . HIS B 1 389 ? 139.335 169.184 117.739 1.00 274.50 ?  389  HIS B CB  1 
ATOM   5640 C CG  . HIS B 1 389 ? 139.260 170.556 117.146 1.00 274.50 ?  389  HIS B CG  1 
ATOM   5641 N ND1 . HIS B 1 389 ? 140.379 171.320 116.896 1.00 274.50 ?  389  HIS B ND1 1 
ATOM   5642 C CD2 . HIS B 1 389 ? 138.202 171.295 116.740 1.00 274.50 ?  389  HIS B CD2 1 
ATOM   5643 C CE1 . HIS B 1 389 ? 140.013 172.473 116.367 1.00 274.50 ?  389  HIS B CE1 1 
ATOM   5644 N NE2 . HIS B 1 389 ? 138.697 172.484 116.262 1.00 274.50 ?  389  HIS B NE2 1 
ATOM   5645 N N   . ARG B 1 390 ? 140.365 165.767 116.884 1.00 261.05 ?  390  ARG B N   1 
ATOM   5646 C CA  . ARG B 1 390 ? 140.004 164.377 117.147 1.00 261.05 ?  390  ARG B CA  1 
ATOM   5647 C C   . ARG B 1 390 ? 139.841 164.052 118.622 1.00 261.05 ?  390  ARG B C   1 
ATOM   5648 O O   . ARG B 1 390 ? 139.081 163.156 118.971 1.00 261.05 ?  390  ARG B O   1 
ATOM   5649 C CB  . ARG B 1 390 ? 141.033 163.434 116.524 1.00 261.05 ?  390  ARG B CB  1 
ATOM   5650 C CG  . ARG B 1 390 ? 141.489 163.846 115.137 1.00 261.05 ?  390  ARG B CG  1 
ATOM   5651 C CD  . ARG B 1 390 ? 141.384 162.686 114.164 1.00 261.05 ?  390  ARG B CD  1 
ATOM   5652 N NE  . ARG B 1 390 ? 141.488 163.128 112.778 1.00 261.05 ?  390  ARG B NE  1 
ATOM   5653 C CZ  . ARG B 1 390 ? 140.554 162.921 111.858 1.00 261.05 ?  390  ARG B CZ  1 
ATOM   5654 N NH1 . ARG B 1 390 ? 139.440 162.276 112.175 1.00 261.05 1  390  ARG B NH1 1 
ATOM   5655 N NH2 . ARG B 1 390 ? 140.731 163.361 110.620 1.00 261.05 ?  390  ARG B NH2 1 
ATOM   5656 N N   . LEU B 1 391 ? 140.550 164.767 119.487 1.00 317.49 ?  391  LEU B N   1 
ATOM   5657 C CA  . LEU B 1 391 ? 140.487 164.482 120.915 1.00 317.49 ?  391  LEU B CA  1 
ATOM   5658 C C   . LEU B 1 391 ? 139.459 165.344 121.626 1.00 317.49 ?  391  LEU B C   1 
ATOM   5659 O O   . LEU B 1 391 ? 139.454 165.421 122.852 1.00 317.49 ?  391  LEU B O   1 
ATOM   5660 C CB  . LEU B 1 391 ? 141.859 164.658 121.564 1.00 317.49 ?  391  LEU B CB  1 
ATOM   5661 C CG  . LEU B 1 391 ? 142.968 163.708 121.112 1.00 317.49 ?  391  LEU B CG  1 
ATOM   5662 C CD1 . LEU B 1 391 ? 144.210 163.907 121.965 1.00 317.49 ?  391  LEU B CD1 1 
ATOM   5663 C CD2 . LEU B 1 391 ? 142.502 162.264 121.176 1.00 317.49 ?  391  LEU B CD2 1 
ATOM   5664 N N   . LEU B 1 392 ? 138.584 165.991 120.866 1.00 322.38 ?  392  LEU B N   1 
ATOM   5665 C CA  . LEU B 1 392 ? 137.536 166.803 121.469 1.00 322.38 ?  392  LEU B CA  1 
ATOM   5666 C C   . LEU B 1 392 ? 136.397 165.921 121.941 1.00 322.38 ?  392  LEU B C   1 
ATOM   5667 O O   . LEU B 1 392 ? 136.017 165.978 123.102 1.00 322.38 ?  392  LEU B O   1 
ATOM   5668 C CB  . LEU B 1 392 ? 137.016 167.849 120.486 1.00 322.38 ?  392  LEU B CB  1 
ATOM   5669 C CG  . LEU B 1 392 ? 136.841 169.265 121.030 1.00 322.38 ?  392  LEU B CG  1 
ATOM   5670 C CD1 . LEU B 1 392 ? 135.391 169.516 121.411 1.00 322.38 ?  392  LEU B CD1 1 
ATOM   5671 C CD2 . LEU B 1 392 ? 137.759 169.495 122.219 1.00 322.38 ?  392  LEU B CD2 1 
ATOM   5672 N N   . TYR B 1 393 ? 135.853 165.103 121.047 1.00 284.68 ?  393  TYR B N   1 
ATOM   5673 C CA  . TYR B 1 393 ? 134.773 164.198 121.427 1.00 284.68 ?  393  TYR B CA  1 
ATOM   5674 C C   . TYR B 1 393 ? 135.130 163.294 122.608 1.00 284.68 ?  393  TYR B C   1 
ATOM   5675 O O   . TYR B 1 393 ? 134.422 163.303 123.611 1.00 284.68 ?  393  TYR B O   1 
ATOM   5676 C CB  . TYR B 1 393 ? 134.253 163.387 120.235 1.00 284.68 ?  393  TYR B CB  1 
ATOM   5677 C CG  . TYR B 1 393 ? 132.981 162.629 120.528 1.00 284.68 ?  393  TYR B CG  1 
ATOM   5678 C CD1 . TYR B 1 393 ? 131.785 163.301 120.727 1.00 284.68 ?  393  TYR B CD1 1 
ATOM   5679 C CD2 . TYR B 1 393 ? 132.976 161.243 120.610 1.00 284.68 ?  393  TYR B CD2 1 
ATOM   5680 C CE1 . TYR B 1 393 ? 130.618 162.615 120.998 1.00 284.68 ?  393  TYR B CE1 1 
ATOM   5681 C CE2 . TYR B 1 393 ? 131.813 160.549 120.881 1.00 284.68 ?  393  TYR B CE2 1 
ATOM   5682 C CZ  . TYR B 1 393 ? 130.638 161.241 121.073 1.00 284.68 ?  393  TYR B CZ  1 
ATOM   5683 O OH  . TYR B 1 393 ? 129.475 160.560 121.344 1.00 284.68 ?  393  TYR B OH  1 
ATOM   5684 N N   . PRO B 1 394 ? 136.230 162.518 122.517 1.00 278.97 ?  394  PRO B N   1 
ATOM   5685 C CA  . PRO B 1 394 ? 136.529 161.716 123.706 1.00 278.97 ?  394  PRO B CA  1 
ATOM   5686 C C   . PRO B 1 394 ? 136.716 162.586 124.934 1.00 278.97 ?  394  PRO B C   1 
ATOM   5687 O O   . PRO B 1 394 ? 136.218 162.236 125.994 1.00 278.97 ?  394  PRO B O   1 
ATOM   5688 C CB  . PRO B 1 394 ? 137.838 161.007 123.346 1.00 278.97 ?  394  PRO B CB  1 
ATOM   5689 C CG  . PRO B 1 394 ? 138.379 161.719 122.161 1.00 278.97 ?  394  PRO B CG  1 
ATOM   5690 C CD  . PRO B 1 394 ? 137.189 162.251 121.432 1.00 278.97 ?  394  PRO B CD  1 
ATOM   5691 N N   . GLY B 1 395 ? 137.401 163.713 124.791 1.00 324.54 ?  395  GLY B N   1 
ATOM   5692 C CA  . GLY B 1 395 ? 137.606 164.617 125.904 1.00 324.54 ?  395  GLY B CA  1 
ATOM   5693 C C   . GLY B 1 395 ? 136.330 165.034 126.595 1.00 324.54 ?  395  GLY B C   1 
ATOM   5694 O O   . GLY B 1 395 ? 136.175 164.806 127.789 1.00 324.54 ?  395  GLY B O   1 
ATOM   5695 N N   . ILE B 1 396 ? 135.406 165.639 125.858 1.00 365.59 ?  396  ILE B N   1 
ATOM   5696 C CA  . ILE B 1 396 ? 134.182 166.133 126.478 1.00 365.59 ?  396  ILE B CA  1 
ATOM   5697 C C   . ILE B 1 396 ? 133.320 165.015 127.056 1.00 365.59 ?  396  ILE B C   1 
ATOM   5698 O O   . ILE B 1 396 ? 132.781 165.160 128.145 1.00 365.59 ?  396  ILE B O   1 
ATOM   5699 C CB  . ILE B 1 396 ? 133.356 167.044 125.537 1.00 365.59 ?  396  ILE B CB  1 
ATOM   5700 C CG1 . ILE B 1 396 ? 132.932 166.304 124.267 1.00 365.59 ?  396  ILE B CG1 1 
ATOM   5701 C CG2 . ILE B 1 396 ? 134.146 168.295 125.185 1.00 365.59 ?  396  ILE B CG2 1 
ATOM   5702 C CD1 . ILE B 1 396 ? 132.520 167.217 123.134 1.00 365.59 ?  396  ILE B CD1 1 
ATOM   5703 N N   . VAL B 1 397 ? 133.209 163.897 126.350 1.00 328.67 ?  397  VAL B N   1 
ATOM   5704 C CA  . VAL B 1 397 ? 132.418 162.787 126.847 1.00 328.67 ?  397  VAL B CA  1 
ATOM   5705 C C   . VAL B 1 397 ? 133.009 162.287 128.156 1.00 328.67 ?  397  VAL B C   1 
ATOM   5706 O O   . VAL B 1 397 ? 132.306 162.188 129.154 1.00 328.67 ?  397  VAL B O   1 
ATOM   5707 C CB  . VAL B 1 397 ? 132.309 161.653 125.813 1.00 328.67 ?  397  VAL B CB  1 
ATOM   5708 C CG1 . VAL B 1 397 ? 131.809 160.375 126.462 1.00 328.67 ?  397  VAL B CG1 1 
ATOM   5709 C CG2 . VAL B 1 397 ? 131.383 162.064 124.683 1.00 328.67 ?  397  VAL B CG2 1 
ATOM   5710 N N   . THR B 1 398 ? 134.306 162.008 128.170 1.00 299.27 ?  398  THR B N   1 
ATOM   5711 C CA  . THR B 1 398 ? 134.958 161.540 129.386 1.00 299.27 ?  398  THR B CA  1 
ATOM   5712 C C   . THR B 1 398 ? 134.771 162.534 130.512 1.00 299.27 ?  398  THR B C   1 
ATOM   5713 O O   . THR B 1 398 ? 134.432 162.155 131.628 1.00 299.27 ?  398  THR B O   1 
ATOM   5714 C CB  . THR B 1 398 ? 136.458 161.311 129.167 1.00 299.27 ?  398  THR B CB  1 
ATOM   5715 O OG1 . THR B 1 398 ? 136.643 160.447 128.043 1.00 299.27 ?  398  THR B OG1 1 
ATOM   5716 C CG2 . THR B 1 398 ? 137.079 160.674 130.382 1.00 299.27 ?  398  THR B CG2 1 
ATOM   5717 N N   . PHE B 1 399 ? 134.974 163.813 130.222 1.00 309.78 ?  399  PHE B N   1 
ATOM   5718 C CA  . PHE B 1 399 ? 134.845 164.830 131.249 1.00 309.78 ?  399  PHE B CA  1 
ATOM   5719 C C   . PHE B 1 399 ? 133.468 164.808 131.882 1.00 309.78 ?  399  PHE B C   1 
ATOM   5720 O O   . PHE B 1 399 ? 133.356 164.743 133.097 1.00 309.78 ?  399  PHE B O   1 
ATOM   5721 C CB  . PHE B 1 399 ? 135.137 166.221 130.697 1.00 309.78 ?  399  PHE B CB  1 
ATOM   5722 C CG  . PHE B 1 399 ? 135.111 167.296 131.742 1.00 309.78 ?  399  PHE B CG  1 
ATOM   5723 C CD1 . PHE B 1 399 ? 136.002 167.268 132.800 1.00 309.78 ?  399  PHE B CD1 1 
ATOM   5724 C CD2 . PHE B 1 399 ? 134.190 168.325 131.674 1.00 309.78 ?  399  PHE B CD2 1 
ATOM   5725 C CE1 . PHE B 1 399 ? 135.979 168.251 133.769 1.00 309.78 ?  399  PHE B CE1 1 
ATOM   5726 C CE2 . PHE B 1 399 ? 134.161 169.311 132.640 1.00 309.78 ?  399  PHE B CE2 1 
ATOM   5727 C CZ  . PHE B 1 399 ? 135.057 169.275 133.689 1.00 309.78 ?  399  PHE B CZ  1 
ATOM   5728 N N   . VAL B 1 400 ? 132.418 164.860 131.071 1.00 287.95 ?  400  VAL B N   1 
ATOM   5729 C CA  . VAL B 1 400 ? 131.075 164.917 131.632 1.00 287.95 ?  400  VAL B CA  1 
ATOM   5730 C C   . VAL B 1 400 ? 130.693 163.634 132.368 1.00 287.95 ?  400  VAL B C   1 
ATOM   5731 O O   . VAL B 1 400 ? 130.020 163.691 133.391 1.00 287.95 ?  400  VAL B O   1 
ATOM   5732 C CB  . VAL B 1 400 ? 130.003 165.334 130.598 1.00 287.95 ?  400  VAL B CB  1 
ATOM   5733 C CG1 . VAL B 1 400 ? 130.370 166.664 129.962 1.00 287.95 ?  400  VAL B CG1 1 
ATOM   5734 C CG2 . VAL B 1 400 ? 129.777 164.263 129.544 1.00 287.95 ?  400  VAL B CG2 1 
ATOM   5735 N N   . ILE B 1 401 ? 131.144 162.485 131.878 1.00 229.00 ?  401  ILE B N   1 
ATOM   5736 C CA  . ILE B 1 401 ? 130.862 161.231 132.559 1.00 229.00 ?  401  ILE B CA  1 
ATOM   5737 C C   . ILE B 1 401 ? 131.524 161.255 133.924 1.00 229.00 ?  401  ILE B C   1 
ATOM   5738 O O   . ILE B 1 401 ? 130.889 160.959 134.932 1.00 229.00 ?  401  ILE B O   1 
ATOM   5739 C CB  . ILE B 1 401 ? 131.354 160.019 131.748 1.00 229.00 ?  401  ILE B CB  1 
ATOM   5740 C CG1 . ILE B 1 401 ? 130.510 159.834 130.491 1.00 229.00 ?  401  ILE B CG1 1 
ATOM   5741 C CG2 . ILE B 1 401 ? 131.318 158.750 132.585 1.00 229.00 ?  401  ILE B CG2 1 
ATOM   5742 C CD1 . ILE B 1 401 ? 130.905 158.620 129.683 1.00 229.00 ?  401  ILE B CD1 1 
ATOM   5743 N N   . ALA B 1 402 ? 132.792 161.645 133.970 1.00 255.59 ?  402  ALA B N   1 
ATOM   5744 C CA  . ALA B 1 402 ? 133.521 161.668 135.231 1.00 255.59 ?  402  ALA B CA  1 
ATOM   5745 C C   . ALA B 1 402 ? 133.038 162.761 136.170 1.00 255.59 ?  402  ALA B C   1 
ATOM   5746 O O   . ALA B 1 402 ? 133.132 162.621 137.384 1.00 255.59 ?  402  ALA B O   1 
ATOM   5747 C CB  . ALA B 1 402 ? 135.009 161.801 134.978 1.00 255.59 ?  402  ALA B CB  1 
ATOM   5748 N N   . SER B 1 403 ? 132.511 163.846 135.618 1.00 271.02 ?  403  SER B N   1 
ATOM   5749 C CA  . SER B 1 403 ? 132.027 164.944 136.441 1.00 271.02 ?  403  SER B CA  1 
ATOM   5750 C C   . SER B 1 403 ? 130.687 164.604 137.058 1.00 271.02 ?  403  SER B C   1 
ATOM   5751 O O   . SER B 1 403 ? 130.297 165.187 138.066 1.00 271.02 ?  403  SER B O   1 
ATOM   5752 C CB  . SER B 1 403 ? 131.912 166.220 135.615 1.00 271.02 ?  403  SER B CB  1 
ATOM   5753 O OG  . SER B 1 403 ? 130.692 166.248 134.898 1.00 271.02 ?  403  SER B OG  1 
ATOM   5754 N N   . PHE B 1 404 ? 129.975 163.659 136.459 1.00 221.39 ?  404  PHE B N   1 
ATOM   5755 C CA  . PHE B 1 404 ? 128.693 163.243 137.003 1.00 221.39 ?  404  PHE B CA  1 
ATOM   5756 C C   . PHE B 1 404 ? 128.859 162.051 137.922 1.00 221.39 ?  404  PHE B C   1 
ATOM   5757 O O   . PHE B 1 404 ? 127.984 161.766 138.731 1.00 221.39 ?  404  PHE B O   1 
ATOM   5758 C CB  . PHE B 1 404 ? 127.716 162.916 135.881 1.00 221.39 ?  404  PHE B CB  1 
ATOM   5759 C CG  . PHE B 1 404 ? 126.889 164.084 135.443 1.00 221.39 ?  404  PHE B CG  1 
ATOM   5760 C CD1 . PHE B 1 404 ? 126.013 164.693 136.321 1.00 221.39 ?  404  PHE B CD1 1 
ATOM   5761 C CD2 . PHE B 1 404 ? 126.990 164.576 134.155 1.00 221.39 ?  404  PHE B CD2 1 
ATOM   5762 C CE1 . PHE B 1 404 ? 125.250 165.771 135.922 1.00 221.39 ?  404  PHE B CE1 1 
ATOM   5763 C CE2 . PHE B 1 404 ? 126.231 165.653 133.747 1.00 221.39 ?  404  PHE B CE2 1 
ATOM   5764 C CZ  . PHE B 1 404 ? 125.359 166.252 134.633 1.00 221.39 ?  404  PHE B CZ  1 
ATOM   5765 N N   . THR B 1 405 ? 129.979 161.350 137.809 1.00 183.45 ?  405  THR B N   1 
ATOM   5766 C CA  . THR B 1 405 ? 130.238 160.232 138.702 1.00 183.45 ?  405  THR B CA  1 
ATOM   5767 C C   . THR B 1 405 ? 131.061 160.684 139.888 1.00 183.45 ?  405  THR B C   1 
ATOM   5768 O O   . THR B 1 405 ? 131.371 159.877 140.753 1.00 183.45 ?  405  THR B O   1 
ATOM   5769 C CB  . THR B 1 405 ? 130.983 159.085 138.002 1.00 183.45 ?  405  THR B CB  1 
ATOM   5770 O OG1 . THR B 1 405 ? 132.120 159.601 137.307 1.00 183.45 ?  405  THR B OG1 1 
ATOM   5771 C CG2 . THR B 1 405 ? 130.075 158.368 137.028 1.00 183.45 ?  405  THR B CG2 1 
ATOM   5772 N N   . PHE B 1 406 ? 131.425 161.963 139.926 1.00 174.21 ?  406  PHE B N   1 
ATOM   5773 C CA  . PHE B 1 406 ? 132.207 162.508 141.032 1.00 174.21 ?  406  PHE B CA  1 
ATOM   5774 C C   . PHE B 1 406 ? 131.532 162.165 142.337 1.00 174.21 ?  406  PHE B C   1 
ATOM   5775 O O   . PHE B 1 406 ? 130.436 162.640 142.601 1.00 174.21 ?  406  PHE B O   1 
ATOM   5776 C CB  . PHE B 1 406 ? 132.331 164.021 140.879 1.00 174.21 ?  406  PHE B CB  1 
ATOM   5777 C CG  . PHE B 1 406 ? 133.236 164.664 141.885 1.00 174.21 ?  406  PHE B CG  1 
ATOM   5778 C CD1 . PHE B 1 406 ? 134.480 164.128 142.160 1.00 174.21 ?  406  PHE B CD1 1 
ATOM   5779 C CD2 . PHE B 1 406 ? 132.845 165.812 142.550 1.00 174.21 ?  406  PHE B CD2 1 
ATOM   5780 C CE1 . PHE B 1 406 ? 135.311 164.716 143.089 1.00 174.21 ?  406  PHE B CE1 1 
ATOM   5781 C CE2 . PHE B 1 406 ? 133.674 166.411 143.475 1.00 174.21 ?  406  PHE B CE2 1 
ATOM   5782 C CZ  . PHE B 1 406 ? 134.910 165.863 143.745 1.00 174.21 ?  406  PHE B CZ  1 
ATOM   5783 N N   . PRO B 1 407 ? 132.184 161.348 143.173 1.00 178.86 ?  407  PRO B N   1 
ATOM   5784 C CA  . PRO B 1 407 ? 131.512 160.901 144.398 1.00 178.86 ?  407  PRO B CA  1 
ATOM   5785 C C   . PRO B 1 407 ? 130.946 161.988 145.328 1.00 178.86 ?  407  PRO B C   1 
ATOM   5786 O O   . PRO B 1 407 ? 129.835 161.801 145.809 1.00 178.86 ?  407  PRO B O   1 
ATOM   5787 C CB  . PRO B 1 407 ? 132.566 160.023 145.083 1.00 178.86 ?  407  PRO B CB  1 
ATOM   5788 C CG  . PRO B 1 407 ? 133.487 159.610 143.988 1.00 178.86 ?  407  PRO B CG  1 
ATOM   5789 C CD  . PRO B 1 407 ? 133.531 160.771 143.044 1.00 178.86 ?  407  PRO B CD  1 
ATOM   5790 N N   . PRO B 1 408 ? 131.672 163.093 145.588 1.00 194.77 ?  408  PRO B N   1 
ATOM   5791 C CA  . PRO B 1 408 ? 131.037 164.110 146.435 1.00 194.77 ?  408  PRO B CA  1 
ATOM   5792 C C   . PRO B 1 408 ? 130.166 165.092 145.669 1.00 194.77 ?  408  PRO B C   1 
ATOM   5793 O O   . PRO B 1 408 ? 129.942 166.198 146.154 1.00 194.77 ?  408  PRO B O   1 
ATOM   5794 C CB  . PRO B 1 408 ? 132.229 164.865 147.033 1.00 194.77 ?  408  PRO B CB  1 
ATOM   5795 C CG  . PRO B 1 408 ? 133.413 163.994 146.804 1.00 194.77 ?  408  PRO B CG  1 
ATOM   5796 C CD  . PRO B 1 408 ? 133.119 163.329 145.502 1.00 194.77 ?  408  PRO B CD  1 
ATOM   5797 N N   . GLY B 1 409 ? 129.682 164.706 144.497 1.00 199.57 ?  409  GLY B N   1 
ATOM   5798 C CA  . GLY B 1 409 ? 128.862 165.590 143.698 1.00 199.57 ?  409  GLY B CA  1 
ATOM   5799 C C   . GLY B 1 409 ? 127.549 164.938 143.349 1.00 199.57 ?  409  GLY B C   1 
ATOM   5800 O O   . GLY B 1 409 ? 126.566 165.087 144.067 1.00 199.57 ?  409  GLY B O   1 
ATOM   5801 N N   . MET B 1 410 ? 127.522 164.214 142.241 1.00 185.66 ?  410  MET B N   1 
ATOM   5802 C CA  . MET B 1 410 ? 126.311 163.523 141.847 1.00 185.66 ?  410  MET B CA  1 
ATOM   5803 C C   . MET B 1 410 ? 126.525 162.039 142.020 1.00 185.66 ?  410  MET B C   1 
ATOM   5804 O O   . MET B 1 410 ? 125.576 161.266 142.009 1.00 185.66 ?  410  MET B O   1 
ATOM   5805 C CB  . MET B 1 410 ? 125.950 163.851 140.401 1.00 185.66 ?  410  MET B CB  1 
ATOM   5806 C CG  . MET B 1 410 ? 124.458 163.950 140.141 1.00 185.66 ?  410  MET B CG  1 
ATOM   5807 S SD  . MET B 1 410 ? 123.871 162.623 139.075 1.00 185.66 ?  410  MET B SD  1 
ATOM   5808 C CE  . MET B 1 410 ? 122.652 161.841 140.129 1.00 185.66 ?  410  MET B CE  1 
ATOM   5809 N N   . GLY B 1 411 ? 127.773 161.637 142.211 1.00 195.24 ?  411  GLY B N   1 
ATOM   5810 C CA  . GLY B 1 411 ? 128.083 160.234 142.387 1.00 195.24 ?  411  GLY B CA  1 
ATOM   5811 C C   . GLY B 1 411 ? 127.625 159.676 143.710 1.00 195.24 ?  411  GLY B C   1 
ATOM   5812 O O   . GLY B 1 411 ? 127.681 158.473 143.924 1.00 195.24 ?  411  GLY B O   1 
ATOM   5813 N N   . GLN B 1 412 ? 127.173 160.539 144.609 1.00 219.13 ?  412  GLN B N   1 
ATOM   5814 C CA  . GLN B 1 412 ? 126.656 160.077 145.884 1.00 219.13 ?  412  GLN B CA  1 
ATOM   5815 C C   . GLN B 1 412 ? 125.249 159.557 145.689 1.00 219.13 ?  412  GLN B C   1 
ATOM   5816 O O   . GLN B 1 412 ? 124.757 158.767 146.491 1.00 219.13 ?  412  GLN B O   1 
ATOM   5817 C CB  . GLN B 1 412 ? 126.653 161.213 146.896 1.00 219.13 ?  412  GLN B CB  1 
ATOM   5818 C CG  . GLN B 1 412 ? 126.540 162.592 146.278 1.00 219.13 ?  412  GLN B CG  1 
ATOM   5819 C CD  . GLN B 1 412 ? 126.417 163.684 147.318 1.00 219.13 ?  412  GLN B CD  1 
ATOM   5820 O OE1 . GLN B 1 412 ? 125.849 163.474 148.387 1.00 219.13 ?  412  GLN B OE1 1 
ATOM   5821 N NE2 . GLN B 1 412 ? 126.950 164.858 147.010 1.00 219.13 ?  412  GLN B NE2 1 
ATOM   5822 N N   . PHE B 1 413 ? 124.597 159.991 144.617 1.00 216.77 ?  413  PHE B N   1 
ATOM   5823 C CA  . PHE B 1 413 ? 123.230 159.574 144.354 1.00 216.77 ?  413  PHE B CA  1 
ATOM   5824 C C   . PHE B 1 413 ? 123.176 158.523 143.265 1.00 216.77 ?  413  PHE B C   1 
ATOM   5825 O O   . PHE B 1 413 ? 122.098 158.132 142.840 1.00 216.77 ?  413  PHE B O   1 
ATOM   5826 C CB  . PHE B 1 413 ? 122.381 160.769 143.930 1.00 216.77 ?  413  PHE B CB  1 
ATOM   5827 C CG  . PHE B 1 413 ? 122.597 161.995 144.761 1.00 216.77 ?  413  PHE B CG  1 
ATOM   5828 C CD1 . PHE B 1 413 ? 122.288 161.998 146.108 1.00 216.77 ?  413  PHE B CD1 1 
ATOM   5829 C CD2 . PHE B 1 413 ? 123.096 163.152 144.190 1.00 216.77 ?  413  PHE B CD2 1 
ATOM   5830 C CE1 . PHE B 1 413 ? 122.482 163.129 146.874 1.00 216.77 ?  413  PHE B CE1 1 
ATOM   5831 C CE2 . PHE B 1 413 ? 123.292 164.287 144.950 1.00 216.77 ?  413  PHE B CE2 1 
ATOM   5832 C CZ  . PHE B 1 413 ? 122.983 164.276 146.294 1.00 216.77 ?  413  PHE B CZ  1 
ATOM   5833 N N   . MET B 1 414 ? 124.333 158.068 142.808 1.00 192.46 ?  414  MET B N   1 
ATOM   5834 C CA  . MET B 1 414 ? 124.374 157.083 141.741 1.00 192.46 ?  414  MET B CA  1 
ATOM   5835 C C   . MET B 1 414 ? 125.519 156.105 141.915 1.00 192.46 ?  414  MET B C   1 
ATOM   5836 O O   . MET B 1 414 ? 125.874 155.416 140.971 1.00 192.46 ?  414  MET B O   1 
ATOM   5837 C CB  . MET B 1 414 ? 124.493 157.775 140.382 1.00 192.46 ?  414  MET B CB  1 
ATOM   5838 C CG  . MET B 1 414 ? 125.776 158.561 140.189 1.00 192.46 ?  414  MET B CG  1 
ATOM   5839 S SD  . MET B 1 414 ? 126.286 158.691 138.469 1.00 192.46 ?  414  MET B SD  1 
ATOM   5840 C CE  . MET B 1 414 ? 126.433 156.965 138.017 1.00 192.46 ?  414  MET B CE  1 
ATOM   5841 N N   . ALA B 1 415 ? 126.094 156.034 143.111 1.00 185.24 ?  415  ALA B N   1 
ATOM   5842 C CA  . ALA B 1 415 ? 127.247 155.163 143.352 1.00 185.24 ?  415  ALA B CA  1 
ATOM   5843 C C   . ALA B 1 415 ? 128.307 155.327 142.274 1.00 185.24 ?  415  ALA B C   1 
ATOM   5844 O O   . ALA B 1 415 ? 128.707 154.355 141.638 1.00 185.24 ?  415  ALA B O   1 
ATOM   5845 C CB  . ALA B 1 415 ? 126.823 153.709 143.479 1.00 185.24 ?  415  ALA B CB  1 
ATOM   5846 N N   . GLY B 1 416 ? 128.768 156.556 142.072 1.00 188.90 ?  416  GLY B N   1 
ATOM   5847 C CA  . GLY B 1 416 ? 129.775 156.816 141.062 1.00 188.90 ?  416  GLY B CA  1 
ATOM   5848 C C   . GLY B 1 416 ? 131.149 156.399 141.522 1.00 188.90 ?  416  GLY B C   1 
ATOM   5849 O O   . GLY B 1 416 ? 132.028 156.158 140.698 1.00 188.90 ?  416  GLY B O   1 
ATOM   5850 N N   . GLU B 1 417 ? 131.346 156.302 142.831 1.00 190.96 ?  417  GLU B N   1 
ATOM   5851 C CA  . GLU B 1 417 ? 132.622 155.844 143.363 1.00 190.96 ?  417  GLU B CA  1 
ATOM   5852 C C   . GLU B 1 417 ? 132.937 154.453 142.856 1.00 190.96 ?  417  GLU B C   1 
ATOM   5853 O O   . GLU B 1 417 ? 134.094 154.121 142.613 1.00 190.96 ?  417  GLU B O   1 
ATOM   5854 C CB  . GLU B 1 417 ? 132.577 155.823 144.887 1.00 190.96 ?  417  GLU B CB  1 
ATOM   5855 C CG  . GLU B 1 417 ? 133.940 155.918 145.551 1.00 190.96 ?  417  GLU B CG  1 
ATOM   5856 C CD  . GLU B 1 417 ? 133.909 156.741 146.821 1.00 190.96 ?  417  GLU B CD  1 
ATOM   5857 O OE1 . GLU B 1 417 ? 134.982 157.210 147.255 1.00 190.96 ?  417  GLU B OE1 1 
ATOM   5858 O OE2 . GLU B 1 417 ? 132.809 156.921 147.386 1.00 190.96 -1 417  GLU B OE2 1 
ATOM   5859 N N   . LEU B 1 418 ? 131.909 153.632 142.695 1.00 187.00 ?  418  LEU B N   1 
ATOM   5860 C CA  . LEU B 1 418 ? 132.111 152.266 142.245 1.00 187.00 ?  418  LEU B CA  1 
ATOM   5861 C C   . LEU B 1 418 ? 132.531 152.200 140.796 1.00 187.00 ?  418  LEU B C   1 
ATOM   5862 O O   . LEU B 1 418 ? 131.954 152.872 139.946 1.00 187.00 ?  418  LEU B O   1 
ATOM   5863 C CB  . LEU B 1 418 ? 130.835 151.457 142.444 1.00 187.00 ?  418  LEU B CB  1 
ATOM   5864 C CG  . LEU B 1 418 ? 130.570 151.016 143.876 1.00 187.00 ?  418  LEU B CG  1 
ATOM   5865 C CD1 . LEU B 1 418 ? 129.691 149.786 143.869 1.00 187.00 ?  418  LEU B CD1 1 
ATOM   5866 C CD2 . LEU B 1 418 ? 131.864 150.746 144.626 1.00 187.00 ?  418  LEU B CD2 1 
ATOM   5867 N N   . MET B 1 419 ? 133.535 151.385 140.510 1.00 204.53 ?  419  MET B N   1 
ATOM   5868 C CA  . MET B 1 419 ? 133.995 151.226 139.142 1.00 204.53 ?  419  MET B CA  1 
ATOM   5869 C C   . MET B 1 419 ? 133.250 150.046 138.544 1.00 204.53 ?  419  MET B C   1 
ATOM   5870 O O   . MET B 1 419 ? 132.701 149.247 139.287 1.00 204.53 ?  419  MET B O   1 
ATOM   5871 C CB  . MET B 1 419 ? 135.509 151.020 139.128 1.00 204.53 ?  419  MET B CB  1 
ATOM   5872 C CG  . MET B 1 419 ? 136.278 152.220 138.597 1.00 204.53 ?  419  MET B CG  1 
ATOM   5873 S SD  . MET B 1 419 ? 136.056 153.728 139.560 1.00 204.53 ?  419  MET B SD  1 
ATOM   5874 C CE  . MET B 1 419 ? 135.133 154.753 138.419 1.00 204.53 ?  419  MET B CE  1 
ATOM   5875 N N   . PRO B 1 420 ? 133.195 149.943 137.205 1.00 156.73 ?  420  PRO B N   1 
ATOM   5876 C CA  . PRO B 1 420 ? 132.423 148.873 136.564 1.00 156.73 ?  420  PRO B CA  1 
ATOM   5877 C C   . PRO B 1 420 ? 132.393 147.538 137.302 1.00 156.73 ?  420  PRO B C   1 
ATOM   5878 O O   . PRO B 1 420 ? 131.309 147.066 137.624 1.00 156.73 ?  420  PRO B O   1 
ATOM   5879 C CB  . PRO B 1 420 ? 133.122 148.725 135.219 1.00 156.73 ?  420  PRO B CB  1 
ATOM   5880 C CG  . PRO B 1 420 ? 133.631 150.101 134.913 1.00 156.73 ?  420  PRO B CG  1 
ATOM   5881 C CD  . PRO B 1 420 ? 133.716 150.884 136.199 1.00 156.73 ?  420  PRO B CD  1 
ATOM   5882 N N   . ARG B 1 421 ? 133.547 146.945 137.572 1.00 168.32 ?  421  ARG B N   1 
ATOM   5883 C CA  . ARG B 1 421 ? 133.594 145.639 138.223 1.00 168.32 ?  421  ARG B CA  1 
ATOM   5884 C C   . ARG B 1 421 ? 133.052 145.662 139.640 1.00 168.32 ?  421  ARG B C   1 
ATOM   5885 O O   . ARG B 1 421 ? 132.348 144.744 140.048 1.00 168.32 ?  421  ARG B O   1 
ATOM   5886 C CB  . ARG B 1 421 ? 135.020 145.101 138.221 1.00 168.32 ?  421  ARG B CB  1 
ATOM   5887 C CG  . ARG B 1 421 ? 135.735 145.284 136.895 1.00 168.32 ?  421  ARG B CG  1 
ATOM   5888 C CD  . ARG B 1 421 ? 135.693 144.010 136.069 1.00 168.32 ?  421  ARG B CD  1 
ATOM   5889 N NE  . ARG B 1 421 ? 137.015 143.406 135.955 1.00 168.32 ?  421  ARG B NE  1 
ATOM   5890 C CZ  . ARG B 1 421 ? 137.366 142.257 136.523 1.00 168.32 ?  421  ARG B CZ  1 
ATOM   5891 N NH1 . ARG B 1 421 ? 136.491 141.574 137.247 1.00 168.32 1  421  ARG B NH1 1 
ATOM   5892 N NH2 . ARG B 1 421 ? 138.594 141.793 136.364 1.00 168.32 ?  421  ARG B NH2 1 
ATOM   5893 N N   . GLU B 1 422 ? 133.374 146.705 140.395 1.00 196.80 ?  422  GLU B N   1 
ATOM   5894 C CA  . GLU B 1 422 ? 132.878 146.823 141.758 1.00 196.80 ?  422  GLU B CA  1 
ATOM   5895 C C   . GLU B 1 422 ? 131.371 146.937 141.763 1.00 196.80 ?  422  GLU B C   1 
ATOM   5896 O O   . GLU B 1 422 ? 130.716 146.402 142.645 1.00 196.80 ?  422  GLU B O   1 
ATOM   5897 C CB  . GLU B 1 422 ? 133.490 148.030 142.457 1.00 196.80 ?  422  GLU B CB  1 
ATOM   5898 C CG  . GLU B 1 422 ? 134.951 148.271 142.132 1.00 196.80 ?  422  GLU B CG  1 
ATOM   5899 C CD  . GLU B 1 422 ? 135.558 149.358 142.994 1.00 196.80 ?  422  GLU B CD  1 
ATOM   5900 O OE1 . GLU B 1 422 ? 136.458 149.045 143.799 1.00 196.80 ?  422  GLU B OE1 1 
ATOM   5901 O OE2 . GLU B 1 422 ? 135.133 150.524 142.872 1.00 196.80 -1 422  GLU B OE2 1 
ATOM   5902 N N   . ALA B 1 423 ? 130.813 147.626 140.776 1.00 179.55 ?  423  ALA B N   1 
ATOM   5903 C CA  . ALA B 1 423 ? 129.367 147.736 140.672 1.00 179.55 ?  423  ALA B CA  1 
ATOM   5904 C C   . ALA B 1 423 ? 128.740 146.362 140.562 1.00 179.55 ?  423  ALA B C   1 
ATOM   5905 O O   . ALA B 1 423 ? 127.870 146.022 141.343 1.00 179.55 ?  423  ALA B O   1 
ATOM   5906 C CB  . ALA B 1 423 ? 128.973 148.596 139.490 1.00 179.55 ?  423  ALA B CB  1 
ATOM   5907 N N   . ILE B 1 424 ? 129.194 145.560 139.607 1.00 178.19 ?  424  ILE B N   1 
ATOM   5908 C CA  . ILE B 1 424 ? 128.656 144.214 139.447 1.00 178.19 ?  424  ILE B CA  1 
ATOM   5909 C C   . ILE B 1 424 ? 128.848 143.364 140.694 1.00 178.19 ?  424  ILE B C   1 
ATOM   5910 O O   . ILE B 1 424 ? 127.972 142.596 141.060 1.00 178.19 ?  424  ILE B O   1 
ATOM   5911 C CB  . ILE B 1 424 ? 129.273 143.481 138.250 1.00 178.19 ?  424  ILE B CB  1 
ATOM   5912 C CG1 . ILE B 1 424 ? 129.606 144.459 137.136 1.00 178.19 ?  424  ILE B CG1 1 
ATOM   5913 C CG2 . ILE B 1 424 ? 128.318 142.432 137.716 1.00 178.19 ?  424  ILE B CG2 1 
ATOM   5914 C CD1 . ILE B 1 424 ? 130.032 143.786 135.854 1.00 178.19 ?  424  ILE B CD1 1 
ATOM   5915 N N   . SER B 1 425 ? 129.986 143.504 141.358 1.00 211.65 ?  425  SER B N   1 
ATOM   5916 C CA  . SER B 1 425 ? 130.260 142.709 142.546 1.00 211.65 ?  425  SER B CA  1 
ATOM   5917 C C   . SER B 1 425 ? 129.319 143.046 143.687 1.00 211.65 ?  425  SER B C   1 
ATOM   5918 O O   . SER B 1 425 ? 128.960 142.176 144.474 1.00 211.65 ?  425  SER B O   1 
ATOM   5919 C CB  . SER B 1 425 ? 131.707 142.898 142.988 1.00 211.65 ?  425  SER B CB  1 
ATOM   5920 O OG  . SER B 1 425 ? 131.801 143.831 144.048 1.00 211.65 ?  425  SER B OG  1 
ATOM   5921 N N   . THR B 1 426 ? 128.916 144.305 143.782 1.00 195.45 ?  426  THR B N   1 
ATOM   5922 C CA  . THR B 1 426 ? 128.018 144.725 144.846 1.00 195.45 ?  426  THR B CA  1 
ATOM   5923 C C   . THR B 1 426 ? 126.569 144.515 144.459 1.00 195.45 ?  426  THR B C   1 
ATOM   5924 O O   . THR B 1 426 ? 125.746 144.190 145.299 1.00 195.45 ?  426  THR B O   1 
ATOM   5925 C CB  . THR B 1 426 ? 128.222 146.200 145.192 1.00 195.45 ?  426  THR B CB  1 
ATOM   5926 O OG1 . THR B 1 426 ? 128.030 146.991 144.016 1.00 195.45 ?  426  THR B OG1 1 
ATOM   5927 C CG2 . THR B 1 426 ? 129.617 146.423 145.730 1.00 195.45 ?  426  THR B CG2 1 
ATOM   5928 N N   . LEU B 1 427 ? 126.248 144.688 143.184 1.00 191.14 ?  427  LEU B N   1 
ATOM   5929 C CA  . LEU B 1 427 ? 124.888 144.458 142.725 1.00 191.14 ?  427  LEU B CA  1 
ATOM   5930 C C   . LEU B 1 427 ? 124.559 142.978 142.788 1.00 191.14 ?  427  LEU B C   1 
ATOM   5931 O O   . LEU B 1 427 ? 123.396 142.605 142.833 1.00 191.14 ?  427  LEU B O   1 
ATOM   5932 C CB  . LEU B 1 427 ? 124.688 144.999 141.310 1.00 191.14 ?  427  LEU B CB  1 
ATOM   5933 C CG  . LEU B 1 427 ? 124.581 146.517 141.160 1.00 191.14 ?  427  LEU B CG  1 
ATOM   5934 C CD1 . LEU B 1 427 ? 124.970 146.962 139.760 1.00 191.14 ?  427  LEU B CD1 1 
ATOM   5935 C CD2 . LEU B 1 427 ? 123.189 147.008 141.507 1.00 191.14 ?  427  LEU B CD2 1 
ATOM   5936 N N   . PHE B 1 428 ? 125.579 142.129 142.807 1.00 213.07 ?  428  PHE B N   1 
ATOM   5937 C CA  . PHE B 1 428 ? 125.363 140.691 142.903 1.00 213.07 ?  428  PHE B CA  1 
ATOM   5938 C C   . PHE B 1 428 ? 125.577 140.242 144.341 1.00 213.07 ?  428  PHE B C   1 
ATOM   5939 O O   . PHE B 1 428 ? 126.024 139.126 144.580 1.00 213.07 ?  428  PHE B O   1 
ATOM   5940 C CB  . PHE B 1 428 ? 126.344 139.936 142.009 1.00 213.07 ?  428  PHE B CB  1 
ATOM   5941 C CG  . PHE B 1 428 ? 126.029 139.994 140.537 1.00 213.07 ?  428  PHE B CG  1 
ATOM   5942 C CD1 . PHE B 1 428 ? 125.052 140.835 140.037 1.00 213.07 ?  428  PHE B CD1 1 
ATOM   5943 C CD2 . PHE B 1 428 ? 126.731 139.198 139.649 1.00 213.07 ?  428  PHE B CD2 1 
ATOM   5944 C CE1 . PHE B 1 428 ? 124.783 140.882 138.685 1.00 213.07 ?  428  PHE B CE1 1 
ATOM   5945 C CE2 . PHE B 1 428 ? 126.463 139.235 138.295 1.00 213.07 ?  428  PHE B CE2 1 
ATOM   5946 C CZ  . PHE B 1 428 ? 125.486 140.079 137.813 1.00 213.07 ?  428  PHE B CZ  1 
ATOM   5947 N N   . ASP B 1 429 ? 125.273 141.107 145.303 1.00 254.83 ?  429  ASP B N   1 
ATOM   5948 C CA  . ASP B 1 429 ? 125.466 140.775 146.713 1.00 254.83 ?  429  ASP B CA  1 
ATOM   5949 C C   . ASP B 1 429 ? 124.377 139.877 147.250 1.00 254.83 ?  429  ASP B C   1 
ATOM   5950 O O   . ASP B 1 429 ? 123.294 139.791 146.677 1.00 254.83 ?  429  ASP B O   1 
ATOM   5951 C CB  . ASP B 1 429 ? 125.512 142.039 147.565 1.00 254.83 ?  429  ASP B CB  1 
ATOM   5952 C CG  . ASP B 1 429 ? 126.749 142.114 148.425 1.00 254.83 ?  429  ASP B CG  1 
ATOM   5953 O OD1 . ASP B 1 429 ? 127.846 141.807 147.915 1.00 254.83 ?  429  ASP B OD1 1 
ATOM   5954 O OD2 . ASP B 1 429 ? 126.625 142.482 149.611 1.00 254.83 -1 429  ASP B OD2 1 
ATOM   5955 N N   . ASN B 1 430 ? 124.648 139.226 148.372 1.00 236.43 ?  430  ASN B N   1 
ATOM   5956 C CA  . ASN B 1 430 ? 123.672 138.334 148.975 1.00 236.43 ?  430  ASN B CA  1 
ATOM   5957 C C   . ASN B 1 430 ? 122.883 139.051 150.054 1.00 236.43 ?  430  ASN B C   1 
ATOM   5958 O O   . ASN B 1 430 ? 122.286 138.416 150.919 1.00 236.43 ?  430  ASN B O   1 
ATOM   5959 C CB  . ASN B 1 430 ? 124.373 137.102 149.547 1.00 236.43 ?  430  ASN B CB  1 
ATOM   5960 C CG  . ASN B 1 430 ? 125.350 137.441 150.657 1.00 236.43 ?  430  ASN B CG  1 
ATOM   5961 O OD1 . ASN B 1 430 ? 126.181 138.339 150.521 1.00 236.43 ?  430  ASN B OD1 1 
ATOM   5962 N ND2 . ASN B 1 430 ? 125.258 136.714 151.763 1.00 236.43 ?  430  ASN B ND2 1 
ATOM   5963 N N   . ASN B 1 431 ? 122.867 140.376 150.002 1.00 238.46 ?  431  ASN B N   1 
ATOM   5964 C CA  . ASN B 1 431 ? 122.164 141.155 151.008 1.00 238.46 ?  431  ASN B CA  1 
ATOM   5965 C C   . ASN B 1 431 ? 120.900 141.778 150.456 1.00 238.46 ?  431  ASN B C   1 
ATOM   5966 O O   . ASN B 1 431 ? 120.583 141.600 149.283 1.00 238.46 ?  431  ASN B O   1 
ATOM   5967 C CB  . ASN B 1 431 ? 123.075 142.256 151.545 1.00 238.46 ?  431  ASN B CB  1 
ATOM   5968 C CG  . ASN B 1 431 ? 124.124 141.729 152.500 1.00 238.46 ?  431  ASN B CG  1 
ATOM   5969 O OD1 . ASN B 1 431 ? 125.296 142.095 152.416 1.00 238.46 ?  431  ASN B OD1 1 
ATOM   5970 N ND2 . ASN B 1 431 ? 123.707 140.866 153.417 1.00 238.46 ?  431  ASN B ND2 1 
ATOM   5971 N N   . THR B 1 432 ? 120.166 142.494 151.298 1.00 235.80 ?  432  THR B N   1 
ATOM   5972 C CA  . THR B 1 432 ? 118.965 143.185 150.853 1.00 235.80 ?  432  THR B CA  1 
ATOM   5973 C C   . THR B 1 432 ? 119.131 144.612 151.303 1.00 235.80 ?  432  THR B C   1 
ATOM   5974 O O   . THR B 1 432 ? 118.859 144.935 152.455 1.00 235.80 ?  432  THR B O   1 
ATOM   5975 C CB  . THR B 1 432 ? 117.697 142.596 151.481 1.00 235.80 ?  432  THR B CB  1 
ATOM   5976 O OG1 . THR B 1 432 ? 117.615 141.198 151.176 1.00 235.80 ?  432  THR B OG1 1 
ATOM   5977 C CG2 . THR B 1 432 ? 116.468 143.295 150.938 1.00 235.80 ?  432  THR B CG2 1 
ATOM   5978 N N   . TRP B 1 433 ? 119.583 145.478 150.410 1.00 195.77 ?  433  TRP B N   1 
ATOM   5979 C CA  . TRP B 1 433 ? 119.863 146.859 150.786 1.00 195.77 ?  433  TRP B CA  1 
ATOM   5980 C C   . TRP B 1 433 ? 118.677 147.584 151.387 1.00 195.77 ?  433  TRP B C   1 
ATOM   5981 O O   . TRP B 1 433 ? 118.850 148.476 152.211 1.00 195.77 ?  433  TRP B O   1 
ATOM   5982 C CB  . TRP B 1 433 ? 120.372 147.630 149.575 1.00 195.77 ?  433  TRP B CB  1 
ATOM   5983 C CG  . TRP B 1 433 ? 121.599 147.058 148.953 1.00 195.77 ?  433  TRP B CG  1 
ATOM   5984 C CD1 . TRP B 1 433 ? 122.534 146.271 149.553 1.00 195.77 ?  433  TRP B CD1 1 
ATOM   5985 C CD2 . TRP B 1 433 ? 122.032 147.235 147.602 1.00 195.77 ?  433  TRP B CD2 1 
ATOM   5986 N NE1 . TRP B 1 433 ? 123.520 145.942 148.661 1.00 195.77 ?  433  TRP B NE1 1 
ATOM   5987 C CE2 . TRP B 1 433 ? 123.236 146.525 147.455 1.00 195.77 ?  433  TRP B CE2 1 
ATOM   5988 C CE3 . TRP B 1 433 ? 121.518 147.923 146.503 1.00 195.77 ?  433  TRP B CE3 1 
ATOM   5989 C CZ2 . TRP B 1 433 ? 123.932 146.484 146.256 1.00 195.77 ?  433  TRP B CZ2 1 
ATOM   5990 C CZ3 . TRP B 1 433 ? 122.211 147.880 145.314 1.00 195.77 ?  433  TRP B CZ3 1 
ATOM   5991 C CH2 . TRP B 1 433 ? 123.403 147.163 145.198 1.00 195.77 ?  433  TRP B CH2 1 
ATOM   5992 N N   . VAL B 1 434 ? 117.472 147.209 150.983 1.00 221.24 ?  434  VAL B N   1 
ATOM   5993 C CA  . VAL B 1 434 ? 116.275 147.881 151.471 1.00 221.24 ?  434  VAL B CA  1 
ATOM   5994 C C   . VAL B 1 434 ? 116.030 147.604 152.954 1.00 221.24 ?  434  VAL B C   1 
ATOM   5995 O O   . VAL B 1 434 ? 115.399 148.407 153.642 1.00 221.24 ?  434  VAL B O   1 
ATOM   5996 C CB  . VAL B 1 434 ? 115.053 147.536 150.589 1.00 221.24 ?  434  VAL B CB  1 
ATOM   5997 C CG1 . VAL B 1 434 ? 114.079 146.601 151.292 1.00 221.24 ?  434  VAL B CG1 1 
ATOM   5998 C CG2 . VAL B 1 434 ? 114.369 148.804 150.111 1.00 221.24 ?  434  VAL B CG2 1 
ATOM   5999 N N   . LYS B 1 435 ? 116.557 146.494 153.458 1.00 239.32 ?  435  LYS B N   1 
ATOM   6000 C CA  . LYS B 1 435 ? 116.381 146.151 154.863 1.00 239.32 ?  435  LYS B CA  1 
ATOM   6001 C C   . LYS B 1 435 ? 117.527 146.687 155.705 1.00 239.32 ?  435  LYS B C   1 
ATOM   6002 O O   . LYS B 1 435 ? 117.325 147.099 156.844 1.00 239.32 ?  435  LYS B O   1 
ATOM   6003 C CB  . LYS B 1 435 ? 116.267 144.636 155.027 1.00 239.32 ?  435  LYS B CB  1 
ATOM   6004 C CG  . LYS B 1 435 ? 114.863 144.101 154.805 1.00 239.32 ?  435  LYS B CG  1 
ATOM   6005 C CD  . LYS B 1 435 ? 114.875 142.610 154.513 1.00 239.32 ?  435  LYS B CD  1 
ATOM   6006 C CE  . LYS B 1 435 ? 113.665 142.204 153.687 1.00 239.32 ?  435  LYS B CE  1 
ATOM   6007 N NZ  . LYS B 1 435 ? 112.851 143.382 153.281 1.00 239.32 1  435  LYS B NZ  1 
ATOM   6008 N N   . HIS B 1 436 ? 118.733 146.689 155.147 1.00 281.37 ?  436  HIS B N   1 
ATOM   6009 C CA  . HIS B 1 436 ? 119.895 147.187 155.874 1.00 281.37 ?  436  HIS B CA  1 
ATOM   6010 C C   . HIS B 1 436 ? 120.210 148.611 155.461 1.00 281.37 ?  436  HIS B C   1 
ATOM   6011 O O   . HIS B 1 436 ? 121.364 148.946 155.212 1.00 281.37 ?  436  HIS B O   1 
ATOM   6012 C CB  . HIS B 1 436 ? 121.118 146.301 155.635 1.00 281.37 ?  436  HIS B CB  1 
ATOM   6013 C CG  . HIS B 1 436 ? 120.791 144.861 155.387 1.00 281.37 ?  436  HIS B CG  1 
ATOM   6014 N ND1 . HIS B 1 436 ? 119.996 144.119 156.234 1.00 281.37 ?  436  HIS B ND1 1 
ATOM   6015 C CD2 . HIS B 1 436 ? 121.165 144.022 154.393 1.00 281.37 ?  436  HIS B CD2 1 
ATOM   6016 C CE1 . HIS B 1 436 ? 119.885 142.889 155.765 1.00 281.37 ?  436  HIS B CE1 1 
ATOM   6017 N NE2 . HIS B 1 436 ? 120.585 142.804 154.649 1.00 281.37 ?  436  HIS B NE2 1 
ATOM   6018 N N   . ALA B 1 437 ? 119.186 149.450 155.377 1.00 293.73 ?  437  ALA B N   1 
ATOM   6019 C CA  . ALA B 1 437 ? 119.395 150.843 155.015 1.00 293.73 ?  437  ALA B CA  1 
ATOM   6020 C C   . ALA B 1 437 ? 119.594 151.642 156.281 1.00 293.73 ?  437  ALA B C   1 
ATOM   6021 O O   . ALA B 1 437 ? 120.385 152.583 156.310 1.00 293.73 ?  437  ALA B O   1 
ATOM   6022 C CB  . ALA B 1 437 ? 118.211 151.374 154.228 1.00 293.73 ?  437  ALA B CB  1 
ATOM   6023 N N   . GLY B 1 438 ? 118.882 151.267 157.339 1.00 306.05 ?  438  GLY B N   1 
ATOM   6024 C CA  . GLY B 1 438 ? 119.057 151.934 158.617 1.00 306.05 ?  438  GLY B CA  1 
ATOM   6025 C C   . GLY B 1 438 ? 120.390 151.535 159.202 1.00 306.05 ?  438  GLY B C   1 
ATOM   6026 O O   . GLY B 1 438 ? 120.951 152.256 160.025 1.00 306.05 ?  438  GLY B O   1 
ATOM   6027 N N   . ASP B 1 439 ? 120.904 150.383 158.786 1.00 298.16 ?  439  ASP B N   1 
ATOM   6028 C CA  . ASP B 1 439 ? 122.216 149.950 159.242 1.00 298.16 ?  439  ASP B CA  1 
ATOM   6029 C C   . ASP B 1 439 ? 123.157 149.763 158.062 1.00 298.16 ?  439  ASP B C   1 
ATOM   6030 O O   . ASP B 1 439 ? 123.260 148.666 157.515 1.00 298.16 ?  439  ASP B O   1 
ATOM   6031 C CB  . ASP B 1 439 ? 122.110 148.645 160.030 1.00 298.16 ?  439  ASP B CB  1 
ATOM   6032 C CG  . ASP B 1 439 ? 123.433 148.228 160.644 1.00 298.16 ?  439  ASP B CG  1 
ATOM   6033 O OD1 . ASP B 1 439 ? 124.161 149.108 161.150 1.00 298.16 ?  439  ASP B OD1 1 
ATOM   6034 O OD2 . ASP B 1 439 ? 123.747 147.021 160.614 1.00 298.16 -1 439  ASP B OD2 1 
ATOM   6035 N N   . PRO B 1 440 ? 123.854 150.834 157.659 1.00 287.15 ?  440  PRO B N   1 
ATOM   6036 C CA  . PRO B 1 440 ? 124.841 150.671 156.594 1.00 287.15 ?  440  PRO B CA  1 
ATOM   6037 C C   . PRO B 1 440 ? 126.157 150.224 157.202 1.00 287.15 ?  440  PRO B C   1 
ATOM   6038 O O   . PRO B 1 440 ? 126.156 149.691 158.313 1.00 287.15 ?  440  PRO B O   1 
ATOM   6039 C CB  . PRO B 1 440 ? 124.979 152.084 156.017 1.00 287.15 ?  440  PRO B CB  1 
ATOM   6040 C CG  . PRO B 1 440 ? 124.268 153.005 156.964 1.00 287.15 ?  440  PRO B CG  1 
ATOM   6041 C CD  . PRO B 1 440 ? 123.816 152.216 158.156 1.00 287.15 ?  440  PRO B CD  1 
ATOM   6042 N N   . GLU B 1 441 ? 127.266 150.438 156.501 1.00 298.65 ?  441  GLU B N   1 
ATOM   6043 C CA  . GLU B 1 441 ? 128.579 150.022 156.996 1.00 298.65 ?  441  GLU B CA  1 
ATOM   6044 C C   . GLU B 1 441 ? 128.542 148.609 157.556 1.00 298.65 ?  441  GLU B C   1 
ATOM   6045 O O   . GLU B 1 441 ? 129.175 148.327 158.571 1.00 298.65 ?  441  GLU B O   1 
ATOM   6046 C CB  . GLU B 1 441 ? 129.101 150.998 158.055 1.00 298.65 ?  441  GLU B CB  1 
ATOM   6047 C CG  . GLU B 1 441 ? 128.839 152.463 157.748 1.00 298.65 ?  441  GLU B CG  1 
ATOM   6048 C CD  . GLU B 1 441 ? 127.830 153.082 158.697 1.00 298.65 ?  441  GLU B CD  1 
ATOM   6049 O OE1 . GLU B 1 441 ? 127.398 152.389 159.642 1.00 298.65 ?  441  GLU B OE1 1 
ATOM   6050 O OE2 . GLU B 1 441 ? 127.467 154.260 158.496 1.00 298.65 -1 441  GLU B OE2 1 
ATOM   6051 N N   . SER B 1 442 ? 127.806 147.720 156.900 1.00 305.90 ?  442  SER B N   1 
ATOM   6052 C CA  . SER B 1 442 ? 127.694 146.345 157.355 1.00 305.90 ?  442  SER B CA  1 
ATOM   6053 C C   . SER B 1 442 ? 127.518 145.515 156.113 1.00 305.90 ?  442  SER B C   1 
ATOM   6054 O O   . SER B 1 442 ? 127.608 144.289 156.155 1.00 305.90 ?  442  SER B O   1 
ATOM   6055 C CB  . SER B 1 442 ? 126.477 146.181 158.257 1.00 305.90 ?  442  SER B CB  1 
ATOM   6056 O OG  . SER B 1 442 ? 125.292 146.566 157.583 1.00 305.90 ?  442  SER B OG  1 
ATOM   6057 N N   . LEU B 1 443 ? 127.267 146.186 154.994 1.00 251.68 ?  443  LEU B N   1 
ATOM   6058 C CA  . LEU B 1 443 ? 127.078 145.488 153.732 1.00 251.68 ?  443  LEU B CA  1 
ATOM   6059 C C   . LEU B 1 443 ? 128.397 145.413 152.995 1.00 251.68 ?  443  LEU B C   1 
ATOM   6060 O O   . LEU B 1 443 ? 128.486 144.797 151.937 1.00 251.68 ?  443  LEU B O   1 
ATOM   6061 C CB  . LEU B 1 443 ? 126.038 146.212 152.888 1.00 251.68 ?  443  LEU B CB  1 
ATOM   6062 C CG  . LEU B 1 443 ? 124.770 146.635 153.623 1.00 251.68 ?  443  LEU B CG  1 
ATOM   6063 C CD1 . LEU B 1 443 ? 124.779 148.129 153.892 1.00 251.68 ?  443  LEU B CD1 1 
ATOM   6064 C CD2 . LEU B 1 443 ? 123.551 146.245 152.812 1.00 251.68 ?  443  LEU B CD2 1 
ATOM   6065 N N   . GLY B 1 444 ? 129.427 146.039 153.552 1.00 215.61 ?  444  GLY B N   1 
ATOM   6066 C CA  . GLY B 1 444 ? 130.741 145.988 152.942 1.00 215.61 ?  444  GLY B CA  1 
ATOM   6067 C C   . GLY B 1 444 ? 130.934 147.051 151.892 1.00 215.61 ?  444  GLY B C   1 
ATOM   6068 O O   . GLY B 1 444 ? 130.777 148.238 152.169 1.00 215.61 ?  444  GLY B O   1 
ATOM   6069 N N   . GLN B 1 445 ? 131.269 146.634 150.678 1.00 206.13 ?  445  GLN B N   1 
ATOM   6070 C CA  . GLN B 1 445 ? 131.445 147.583 149.588 1.00 206.13 ?  445  GLN B CA  1 
ATOM   6071 C C   . GLN B 1 445 ? 130.096 147.986 149.025 1.00 206.13 ?  445  GLN B C   1 
ATOM   6072 O O   . GLN B 1 445 ? 130.012 148.889 148.198 1.00 206.13 ?  445  GLN B O   1 
ATOM   6073 C CB  . GLN B 1 445 ? 132.308 146.970 148.492 1.00 206.13 ?  445  GLN B CB  1 
ATOM   6074 C CG  . GLN B 1 445 ? 133.509 147.814 148.108 1.00 206.13 ?  445  GLN B CG  1 
ATOM   6075 C CD  . GLN B 1 445 ? 133.730 147.860 146.611 1.00 206.13 ?  445  GLN B CD  1 
ATOM   6076 O OE1 . GLN B 1 445 ? 133.190 147.043 145.866 1.00 206.13 ?  445  GLN B OE1 1 
ATOM   6077 N NE2 . GLN B 1 445 ? 134.530 148.818 146.163 1.00 206.13 ?  445  GLN B NE2 1 
ATOM   6078 N N   . SER B 1 446 ? 129.037 147.327 149.478 1.00 199.99 ?  446  SER B N   1 
ATOM   6079 C CA  . SER B 1 446 ? 127.701 147.630 149.000 1.00 199.99 ?  446  SER B CA  1 
ATOM   6080 C C   . SER B 1 446 ? 127.041 148.686 149.862 1.00 199.99 ?  446  SER B C   1 
ATOM   6081 O O   . SER B 1 446 ? 125.840 148.910 149.759 1.00 199.99 ?  446  SER B O   1 
ATOM   6082 C CB  . SER B 1 446 ? 126.864 146.359 148.992 1.00 199.99 ?  446  SER B CB  1 
ATOM   6083 O OG  . SER B 1 446 ? 127.691 145.216 148.897 1.00 199.99 ?  446  SER B OG  1 
ATOM   6084 N N   . ALA B 1 447 ? 127.823 149.344 150.706 1.00 185.10 ?  447  ALA B N   1 
ATOM   6085 C CA  . ALA B 1 447 ? 127.286 150.388 151.568 1.00 185.10 ?  447  ALA B CA  1 
ATOM   6086 C C   . ALA B 1 447 ? 127.323 151.734 150.871 1.00 185.10 ?  447  ALA B C   1 
ATOM   6087 O O   . ALA B 1 447 ? 126.823 152.723 151.401 1.00 185.10 ?  447  ALA B O   1 
ATOM   6088 C CB  . ALA B 1 447 ? 128.060 150.444 152.870 1.00 185.10 ?  447  ALA B CB  1 
ATOM   6089 N N   . VAL B 1 448 ? 127.910 151.779 149.680 1.00 148.45 ?  448  VAL B N   1 
ATOM   6090 C CA  . VAL B 1 448 ? 127.957 153.017 148.913 1.00 148.45 ?  448  VAL B CA  1 
ATOM   6091 C C   . VAL B 1 448 ? 126.623 153.240 148.233 1.00 148.45 ?  448  VAL B C   1 
ATOM   6092 O O   . VAL B 1 448 ? 126.340 154.336 147.753 1.00 148.45 ?  448  VAL B O   1 
ATOM   6093 C CB  . VAL B 1 448 ? 129.055 152.965 147.842 1.00 148.45 ?  448  VAL B CB  1 
ATOM   6094 C CG1 . VAL B 1 448 ? 130.421 152.817 148.492 1.00 148.45 ?  448  VAL B CG1 1 
ATOM   6095 C CG2 . VAL B 1 448 ? 128.797 151.818 146.887 1.00 148.45 ?  448  VAL B CG2 1 
ATOM   6096 N N   . TRP B 1 449 ? 125.796 152.204 148.192 1.00 178.59 ?  449  TRP B N   1 
ATOM   6097 C CA  . TRP B 1 449 ? 124.493 152.314 147.568 1.00 178.59 ?  449  TRP B CA  1 
ATOM   6098 C C   . TRP B 1 449 ? 123.514 152.899 148.557 1.00 178.59 ?  449  TRP B C   1 
ATOM   6099 O O   . TRP B 1 449 ? 122.532 153.522 148.176 1.00 178.59 ?  449  TRP B O   1 
ATOM   6100 C CB  . TRP B 1 449 ? 124.020 150.943 147.108 1.00 178.59 ?  449  TRP B CB  1 
ATOM   6101 C CG  . TRP B 1 449 ? 124.852 150.371 146.021 1.00 178.59 ?  449  TRP B CG  1 
ATOM   6102 C CD1 . TRP B 1 449 ? 125.943 149.570 146.163 1.00 178.59 ?  449  TRP B CD1 1 
ATOM   6103 C CD2 . TRP B 1 449 ? 124.664 150.550 144.615 1.00 178.59 ?  449  TRP B CD2 1 
ATOM   6104 N NE1 . TRP B 1 449 ? 126.448 149.239 144.933 1.00 178.59 ?  449  TRP B NE1 1 
ATOM   6105 C CE2 . TRP B 1 449 ? 125.680 149.828 143.964 1.00 178.59 ?  449  TRP B CE2 1 
ATOM   6106 C CE3 . TRP B 1 449 ? 123.732 151.248 143.842 1.00 178.59 ?  449  TRP B CE3 1 
ATOM   6107 C CZ2 . TRP B 1 449 ? 125.795 149.787 142.580 1.00 178.59 ?  449  TRP B CZ2 1 
ATOM   6108 C CZ3 . TRP B 1 449 ? 123.847 151.206 142.471 1.00 178.59 ?  449  TRP B CZ3 1 
ATOM   6109 C CH2 . TRP B 1 449 ? 124.871 150.481 141.852 1.00 178.59 ?  449  TRP B CH2 1 
ATOM   6110 N N   . ILE B 1 450 ? 123.780 152.702 149.839 1.00 153.23 ?  450  ILE B N   1 
ATOM   6111 C CA  . ILE B 1 450 ? 122.912 153.263 150.858 1.00 153.23 ?  450  ILE B CA  1 
ATOM   6112 C C   . ILE B 1 450 ? 123.316 154.708 151.099 1.00 153.23 ?  450  ILE B C   1 
ATOM   6113 O O   . ILE B 1 450 ? 124.381 154.983 151.652 1.00 153.23 ?  450  ILE B O   1 
ATOM   6114 C CB  . ILE B 1 450 ? 122.927 152.432 152.158 1.00 153.23 ?  450  ILE B CB  1 
ATOM   6115 C CG1 . ILE B 1 450 ? 122.102 151.156 151.980 1.00 153.23 ?  450  ILE B CG1 1 
ATOM   6116 C CG2 . ILE B 1 450 ? 122.342 153.223 153.316 1.00 153.23 ?  450  ILE B CG2 1 
ATOM   6117 C CD1 . ILE B 1 450 ? 122.871 149.979 151.427 1.00 153.23 ?  450  ILE B CD1 1 
ATOM   6118 N N   . HIS B 1 451 ? 122.485 155.637 150.643 1.00 176.34 ?  451  HIS B N   1 
ATOM   6119 C CA  . HIS B 1 451 ? 122.769 157.047 150.848 1.00 176.34 ?  451  HIS B CA  1 
ATOM   6120 C C   . HIS B 1 451 ? 122.056 157.489 152.106 1.00 176.34 ?  451  HIS B C   1 
ATOM   6121 O O   . HIS B 1 451 ? 120.920 157.083 152.339 1.00 176.34 ?  451  HIS B O   1 
ATOM   6122 C CB  . HIS B 1 451 ? 122.290 157.866 149.649 1.00 176.34 ?  451  HIS B CB  1 
ATOM   6123 C CG  . HIS B 1 451 ? 122.686 159.307 149.703 1.00 176.34 ?  451  HIS B CG  1 
ATOM   6124 N ND1 . HIS B 1 451 ? 123.943 159.746 149.349 1.00 176.34 ?  451  HIS B ND1 1 
ATOM   6125 C CD2 . HIS B 1 451 ? 121.994 160.410 150.075 1.00 176.34 ?  451  HIS B CD2 1 
ATOM   6126 C CE1 . HIS B 1 451 ? 124.008 161.057 149.500 1.00 176.34 ?  451  HIS B CE1 1 
ATOM   6127 N NE2 . HIS B 1 451 ? 122.838 161.484 149.939 1.00 176.34 ?  451  HIS B NE2 1 
ATOM   6128 N N   . PRO B 1 452 ? 122.718 158.307 152.937 1.00 207.20 ?  452  PRO B N   1 
ATOM   6129 C CA  . PRO B 1 452 ? 122.099 158.819 154.162 1.00 207.20 ?  452  PRO B CA  1 
ATOM   6130 C C   . PRO B 1 452 ? 120.640 159.225 153.987 1.00 207.20 ?  452  PRO B C   1 
ATOM   6131 O O   . PRO B 1 452 ? 119.799 158.810 154.783 1.00 207.20 ?  452  PRO B O   1 
ATOM   6132 C CB  . PRO B 1 452 ? 122.943 160.051 154.471 1.00 207.20 ?  452  PRO B CB  1 
ATOM   6133 C CG  . PRO B 1 452 ? 124.292 159.741 153.904 1.00 207.20 ?  452  PRO B CG  1 
ATOM   6134 C CD  . PRO B 1 452 ? 124.145 158.664 152.861 1.00 207.20 ?  452  PRO B CD  1 
ATOM   6135 N N   . ARG B 1 453 ? 120.340 160.022 152.969 1.00 216.41 ?  453  ARG B N   1 
ATOM   6136 C CA  . ARG B 1 453 ? 118.975 160.481 152.748 1.00 216.41 ?  453  ARG B CA  1 
ATOM   6137 C C   . ARG B 1 453 ? 118.270 159.692 151.659 1.00 216.41 ?  453  ARG B C   1 
ATOM   6138 O O   . ARG B 1 453 ? 117.312 158.975 151.938 1.00 216.41 ?  453  ARG B O   1 
ATOM   6139 C CB  . ARG B 1 453 ? 118.972 161.966 152.395 1.00 216.41 ?  453  ARG B CB  1 
ATOM   6140 C CG  . ARG B 1 453 ? 120.014 162.782 153.139 1.00 216.41 ?  453  ARG B CG  1 
ATOM   6141 C CD  . ARG B 1 453 ? 120.846 163.613 152.179 1.00 216.41 ?  453  ARG B CD  1 
ATOM   6142 N NE  . ARG B 1 453 ? 120.137 163.868 150.929 1.00 216.41 ?  453  ARG B NE  1 
ATOM   6143 C CZ  . ARG B 1 453 ? 120.666 164.495 149.884 1.00 216.41 ?  453  ARG B CZ  1 
ATOM   6144 N NH1 . ARG B 1 453 ? 119.946 164.685 148.788 1.00 216.41 1  453  ARG B NH1 1 
ATOM   6145 N NH2 . ARG B 1 453 ? 121.917 164.932 149.935 1.00 216.41 ?  453  ARG B NH2 1 
ATOM   6146 N N   . VAL B 1 454 ? 118.734 159.817 150.421 1.00 199.01 ?  454  VAL B N   1 
ATOM   6147 C CA  . VAL B 1 454 ? 118.089 159.140 149.297 1.00 199.01 ?  454  VAL B CA  1 
ATOM   6148 C C   . VAL B 1 454 ? 117.969 157.632 149.488 1.00 199.01 ?  454  VAL B C   1 
ATOM   6149 O O   . VAL B 1 454 ? 118.955 156.959 149.776 1.00 199.01 ?  454  VAL B O   1 
ATOM   6150 C CB  . VAL B 1 454 ? 118.819 159.455 147.978 1.00 199.01 ?  454  VAL B CB  1 
ATOM   6151 C CG1 . VAL B 1 454 ? 117.991 159.021 146.782 1.00 199.01 ?  454  VAL B CG1 1 
ATOM   6152 C CG2 . VAL B 1 454 ? 119.125 160.941 147.894 1.00 199.01 ?  454  VAL B CG2 1 
ATOM   6153 N N   . ASN B 1 455 ? 116.762 157.099 149.327 1.00 173.98 ?  455  ASN B N   1 
ATOM   6154 C CA  . ASN B 1 455 ? 116.532 155.666 149.503 1.00 173.98 ?  455  ASN B CA  1 
ATOM   6155 C C   . ASN B 1 455 ? 117.287 154.844 148.476 1.00 173.98 ?  455  ASN B C   1 
ATOM   6156 O O   . ASN B 1 455 ? 117.361 155.232 147.318 1.00 173.98 ?  455  ASN B O   1 
ATOM   6157 C CB  . ASN B 1 455 ? 115.034 155.366 149.414 1.00 173.98 ?  455  ASN B CB  1 
ATOM   6158 C CG  . ASN B 1 455 ? 114.714 153.900 149.622 1.00 173.98 ?  455  ASN B CG  1 
ATOM   6159 O OD1 . ASN B 1 455 ? 115.256 153.253 150.517 1.00 173.98 ?  455  ASN B OD1 1 
ATOM   6160 N ND2 . ASN B 1 455 ? 113.826 153.369 148.794 1.00 173.98 ?  455  ASN B ND2 1 
ATOM   6161 N N   . VAL B 1 456 ? 117.831 153.704 148.890 1.00 157.56 ?  456  VAL B N   1 
ATOM   6162 C CA  . VAL B 1 456 ? 118.588 152.841 147.984 1.00 157.56 ?  456  VAL B CA  1 
ATOM   6163 C C   . VAL B 1 456 ? 117.948 152.660 146.621 1.00 157.56 ?  456  VAL B C   1 
ATOM   6164 O O   . VAL B 1 456 ? 118.615 152.808 145.609 1.00 157.56 ?  456  VAL B O   1 
ATOM   6165 C CB  . VAL B 1 456 ? 118.808 151.447 148.584 1.00 157.56 ?  456  VAL B CB  1 
ATOM   6166 C CG1 . VAL B 1 456 ? 120.205 150.958 148.251 1.00 157.56 ?  456  VAL B CG1 1 
ATOM   6167 C CG2 . VAL B 1 456 ? 118.585 151.475 150.087 1.00 157.56 ?  456  VAL B CG2 1 
ATOM   6168 N N   . VAL B 1 457 ? 116.662 152.335 146.588 1.00 156.78 ?  457  VAL B N   1 
ATOM   6169 C CA  . VAL B 1 457 ? 115.965 152.121 145.325 1.00 156.78 ?  457  VAL B CA  1 
ATOM   6170 C C   . VAL B 1 457 ? 116.166 153.285 144.365 1.00 156.78 ?  457  VAL B C   1 
ATOM   6171 O O   . VAL B 1 457 ? 116.471 153.083 143.193 1.00 156.78 ?  457  VAL B O   1 
ATOM   6172 C CB  . VAL B 1 457 ? 114.465 151.866 145.563 1.00 156.78 ?  457  VAL B CB  1 
ATOM   6173 C CG1 . VAL B 1 457 ? 113.726 151.693 144.247 1.00 156.78 ?  457  VAL B CG1 1 
ATOM   6174 C CG2 . VAL B 1 457 ? 114.279 150.637 146.437 1.00 156.78 ?  457  VAL B CG2 1 
ATOM   6175 N N   . ILE B 1 458 ? 116.026 154.507 144.860 1.00 182.65 ?  458  ILE B N   1 
ATOM   6176 C CA  . ILE B 1 458 ? 116.201 155.678 144.013 1.00 182.65 ?  458  ILE B CA  1 
ATOM   6177 C C   . ILE B 1 458 ? 117.639 155.856 143.535 1.00 182.65 ?  458  ILE B C   1 
ATOM   6178 O O   . ILE B 1 458 ? 117.861 156.307 142.419 1.00 182.65 ?  458  ILE B O   1 
ATOM   6179 C CB  . ILE B 1 458 ? 115.718 156.962 144.709 1.00 182.65 ?  458  ILE B CB  1 
ATOM   6180 C CG1 . ILE B 1 458 ? 114.563 156.644 145.658 1.00 182.65 ?  458  ILE B CG1 1 
ATOM   6181 C CG2 . ILE B 1 458 ? 115.285 157.998 143.685 1.00 182.65 ?  458  ILE B CG2 1 
ATOM   6182 C CD1 . ILE B 1 458 ? 114.018 157.857 146.377 1.00 182.65 ?  458  ILE B CD1 1 
ATOM   6183 N N   . ILE B 1 459 ? 118.619 155.496 144.356 1.00 168.11 ?  459  ILE B N   1 
ATOM   6184 C CA  . ILE B 1 459 ? 120.007 155.578 143.907 1.00 168.11 ?  459  ILE B CA  1 
ATOM   6185 C C   . ILE B 1 459 ? 120.341 154.504 142.872 1.00 168.11 ?  459  ILE B C   1 
ATOM   6186 O O   . ILE B 1 459 ? 121.146 154.747 141.980 1.00 168.11 ?  459  ILE B O   1 
ATOM   6187 C CB  . ILE B 1 459 ? 121.034 155.638 145.069 1.00 168.11 ?  459  ILE B CB  1 
ATOM   6188 C CG1 . ILE B 1 459 ? 121.941 154.410 145.088 1.00 168.11 ?  459  ILE B CG1 1 
ATOM   6189 C CG2 . ILE B 1 459 ? 120.351 155.858 146.406 1.00 168.11 ?  459  ILE B CG2 1 
ATOM   6190 C CD1 . ILE B 1 459 ? 123.407 154.765 144.998 1.00 168.11 ?  459  ILE B CD1 1 
ATOM   6191 N N   . ILE B 1 460 ? 119.709 153.336 142.955 1.00 157.05 ?  460  ILE B N   1 
ATOM   6192 C CA  . ILE B 1 460 ? 119.920 152.310 141.938 1.00 157.05 ?  460  ILE B CA  1 
ATOM   6193 C C   . ILE B 1 460 ? 119.262 152.790 140.662 1.00 157.05 ?  460  ILE B C   1 
ATOM   6194 O O   . ILE B 1 460 ? 119.774 152.568 139.570 1.00 157.05 ?  460  ILE B O   1 
ATOM   6195 C CB  . ILE B 1 460 ? 119.317 150.951 142.339 1.00 157.05 ?  460  ILE B CB  1 
ATOM   6196 C CG1 . ILE B 1 460 ? 119.758 150.546 143.740 1.00 157.05 ?  460  ILE B CG1 1 
ATOM   6197 C CG2 . ILE B 1 460 ? 119.749 149.867 141.371 1.00 157.05 ?  460  ILE B CG2 1 
ATOM   6198 C CD1 . ILE B 1 460 ? 118.883 149.473 144.348 1.00 157.05 ?  460  ILE B CD1 1 
ATOM   6199 N N   . PHE B 1 461 ? 118.129 153.465 140.795 1.00 201.00 ?  461  PHE B N   1 
ATOM   6200 C CA  . PHE B 1 461 ? 117.443 154.004 139.634 1.00 201.00 ?  461  PHE B CA  1 
ATOM   6201 C C   . PHE B 1 461 ? 118.310 155.051 138.972 1.00 201.00 ?  461  PHE B C   1 
ATOM   6202 O O   . PHE B 1 461 ? 118.479 155.042 137.760 1.00 201.00 ?  461  PHE B O   1 
ATOM   6203 C CB  . PHE B 1 461 ? 116.113 154.622 140.057 1.00 201.00 ?  461  PHE B CB  1 
ATOM   6204 C CG  . PHE B 1 461 ? 115.380 155.311 138.946 1.00 201.00 ?  461  PHE B CG  1 
ATOM   6205 C CD1 . PHE B 1 461 ? 114.842 154.586 137.899 1.00 201.00 ?  461  PHE B CD1 1 
ATOM   6206 C CD2 . PHE B 1 461 ? 115.221 156.686 138.956 1.00 201.00 ?  461  PHE B CD2 1 
ATOM   6207 C CE1 . PHE B 1 461 ? 114.164 155.218 136.877 1.00 201.00 ?  461  PHE B CE1 1 
ATOM   6208 C CE2 . PHE B 1 461 ? 114.546 157.326 137.937 1.00 201.00 ?  461  PHE B CE2 1 
ATOM   6209 C CZ  . PHE B 1 461 ? 114.015 156.591 136.896 1.00 201.00 ?  461  PHE B CZ  1 
ATOM   6210 N N   . LEU B 1 462 ? 118.868 155.954 139.766 1.00 190.40 ?  462  LEU B N   1 
ATOM   6211 C CA  . LEU B 1 462 ? 119.701 157.012 139.218 1.00 190.40 ?  462  LEU B CA  1 
ATOM   6212 C C   . LEU B 1 462 ? 120.962 156.432 138.620 1.00 190.40 ?  462  LEU B C   1 
ATOM   6213 O O   . LEU B 1 462 ? 121.441 156.928 137.616 1.00 190.40 ?  462  LEU B O   1 
ATOM   6214 C CB  . LEU B 1 462 ? 120.041 158.039 140.289 1.00 190.40 ?  462  LEU B CB  1 
ATOM   6215 C CG  . LEU B 1 462 ? 119.261 159.352 140.291 1.00 190.40 ?  462  LEU B CG  1 
ATOM   6216 C CD1 . LEU B 1 462 ? 118.112 159.312 139.297 1.00 190.40 ?  462  LEU B CD1 1 
ATOM   6217 C CD2 . LEU B 1 462 ? 118.761 159.669 141.691 1.00 190.40 ?  462  LEU B CD2 1 
ATOM   6218 N N   . PHE B 1 463 ? 121.504 155.380 139.221 1.00 168.22 ?  463  PHE B N   1 
ATOM   6219 C CA  . PHE B 1 463 ? 122.666 154.716 138.649 1.00 168.22 ?  463  PHE B CA  1 
ATOM   6220 C C   . PHE B 1 463 ? 122.295 154.247 137.262 1.00 168.22 ?  463  PHE B C   1 
ATOM   6221 O O   . PHE B 1 463 ? 122.972 154.567 136.302 1.00 168.22 ?  463  PHE B O   1 
ATOM   6222 C CB  . PHE B 1 463 ? 123.085 153.527 139.513 1.00 168.22 ?  463  PHE B CB  1 
ATOM   6223 C CG  . PHE B 1 463 ? 124.204 152.702 138.933 1.00 168.22 ?  463  PHE B CG  1 
ATOM   6224 C CD1 . PHE B 1 463 ? 125.519 153.107 139.057 1.00 168.22 ?  463  PHE B CD1 1 
ATOM   6225 C CD2 . PHE B 1 463 ? 123.942 151.507 138.291 1.00 168.22 ?  463  PHE B CD2 1 
ATOM   6226 C CE1 . PHE B 1 463 ? 126.548 152.347 138.541 1.00 168.22 ?  463  PHE B CE1 1 
ATOM   6227 C CE2 . PHE B 1 463 ? 124.964 150.742 137.767 1.00 168.22 ?  463  PHE B CE2 1 
ATOM   6228 C CZ  . PHE B 1 463 ? 126.270 151.162 137.893 1.00 168.22 ?  463  PHE B CZ  1 
ATOM   6229 N N   . PHE B 1 464 ? 121.207 153.499 137.152 1.00 193.47 ?  464  PHE B N   1 
ATOM   6230 C CA  . PHE B 1 464 ? 120.775 152.986 135.861 1.00 193.47 ?  464  PHE B CA  1 
ATOM   6231 C C   . PHE B 1 464 ? 120.584 154.096 134.840 1.00 193.47 ?  464  PHE B C   1 
ATOM   6232 O O   . PHE B 1 464 ? 121.080 153.997 133.728 1.00 193.47 ?  464  PHE B O   1 
ATOM   6233 C CB  . PHE B 1 464 ? 119.486 152.177 136.015 1.00 193.47 ?  464  PHE B CB  1 
ATOM   6234 C CG  . PHE B 1 464 ? 118.968 151.615 134.726 1.00 193.47 ?  464  PHE B CG  1 
ATOM   6235 C CD1 . PHE B 1 464 ? 119.548 150.494 134.170 1.00 193.47 ?  464  PHE B CD1 1 
ATOM   6236 C CD2 . PHE B 1 464 ? 117.904 152.209 134.072 1.00 193.47 ?  464  PHE B CD2 1 
ATOM   6237 C CE1 . PHE B 1 464 ? 119.081 149.972 132.983 1.00 193.47 ?  464  PHE B CE1 1 
ATOM   6238 C CE2 . PHE B 1 464 ? 117.433 151.694 132.883 1.00 193.47 ?  464  PHE B CE2 1 
ATOM   6239 C CZ  . PHE B 1 464 ? 118.023 150.572 132.339 1.00 193.47 ?  464  PHE B CZ  1 
ATOM   6240 N N   . VAL B 1 465 ? 119.866 155.148 135.207 1.00 202.93 ?  465  VAL B N   1 
ATOM   6241 C CA  . VAL B 1 465 ? 119.593 156.235 134.274 1.00 202.93 ?  465  VAL B CA  1 
ATOM   6242 C C   . VAL B 1 465 ? 120.876 156.927 133.856 1.00 202.93 ?  465  VAL B C   1 
ATOM   6243 O O   . VAL B 1 465 ? 121.137 157.109 132.664 1.00 202.93 ?  465  VAL B O   1 
ATOM   6244 C CB  . VAL B 1 465 ? 118.619 157.253 134.892 1.00 202.93 ?  465  VAL B CB  1 
ATOM   6245 C CG1 . VAL B 1 465 ? 118.562 158.530 134.068 1.00 202.93 ?  465  VAL B CG1 1 
ATOM   6246 C CG2 . VAL B 1 465 ? 117.237 156.640 135.014 1.00 202.93 ?  465  VAL B CG2 1 
ATOM   6247 N N   . MET B 1 466 ? 121.695 157.292 134.832 1.00 206.60 ?  466  MET B N   1 
ATOM   6248 C CA  . MET B 1 466 ? 122.941 157.976 134.535 1.00 206.60 ?  466  MET B CA  1 
ATOM   6249 C C   . MET B 1 466 ? 123.857 157.107 133.705 1.00 206.60 ?  466  MET B C   1 
ATOM   6250 O O   . MET B 1 466 ? 124.385 157.548 132.699 1.00 206.60 ?  466  MET B O   1 
ATOM   6251 C CB  . MET B 1 466 ? 123.638 158.401 135.820 1.00 206.60 ?  466  MET B CB  1 
ATOM   6252 C CG  . MET B 1 466 ? 123.780 159.903 135.981 1.00 206.60 ?  466  MET B CG  1 
ATOM   6253 S SD  . MET B 1 466 ? 122.203 160.765 135.896 1.00 206.60 ?  466  MET B SD  1 
ATOM   6254 C CE  . MET B 1 466 ? 122.739 162.373 135.319 1.00 206.60 ?  466  MET B CE  1 
ATOM   6255 N N   . LYS B 1 467 ? 124.034 155.860 134.109 1.00 171.12 ?  467  LYS B N   1 
ATOM   6256 C CA  . LYS B 1 467 ? 124.933 154.973 133.393 1.00 171.12 ?  467  LYS B CA  1 
ATOM   6257 C C   . LYS B 1 467 ? 124.371 154.507 132.063 1.00 171.12 ?  467  LYS B C   1 
ATOM   6258 O O   . LYS B 1 467 ? 125.088 153.915 131.274 1.00 171.12 ?  467  LYS B O   1 
ATOM   6259 C CB  . LYS B 1 467 ? 125.329 153.780 134.261 1.00 171.12 ?  467  LYS B CB  1 
ATOM   6260 C CG  . LYS B 1 467 ? 126.444 154.084 135.243 1.00 171.12 ?  467  LYS B CG  1 
ATOM   6261 C CD  . LYS B 1 467 ? 127.798 153.716 134.665 1.00 171.12 ?  467  LYS B CD  1 
ATOM   6262 C CE  . LYS B 1 467 ? 128.924 154.139 135.593 1.00 171.12 ?  467  LYS B CE  1 
ATOM   6263 N NZ  . LYS B 1 467 ? 129.771 155.200 134.983 1.00 171.12 1  467  LYS B NZ  1 
ATOM   6264 N N   . PHE B 1 468 ? 123.096 154.765 131.803 1.00 195.61 ?  468  PHE B N   1 
ATOM   6265 C CA  . PHE B 1 468 ? 122.523 154.415 130.513 1.00 195.61 ?  468  PHE B CA  1 
ATOM   6266 C C   . PHE B 1 468 ? 123.103 155.337 129.468 1.00 195.61 ?  468  PHE B C   1 
ATOM   6267 O O   . PHE B 1 468 ? 123.713 154.884 128.505 1.00 195.61 ?  468  PHE B O   1 
ATOM   6268 C CB  . PHE B 1 468 ? 121.003 154.539 130.531 1.00 195.61 ?  468  PHE B CB  1 
ATOM   6269 C CG  . PHE B 1 468 ? 120.303 153.589 129.607 1.00 195.61 ?  468  PHE B CG  1 
ATOM   6270 C CD1 . PHE B 1 468 ? 120.229 152.242 129.905 1.00 195.61 ?  468  PHE B CD1 1 
ATOM   6271 C CD2 . PHE B 1 468 ? 119.714 154.046 128.442 1.00 195.61 ?  468  PHE B CD2 1 
ATOM   6272 C CE1 . PHE B 1 468 ? 119.584 151.364 129.057 1.00 195.61 ?  468  PHE B CE1 1 
ATOM   6273 C CE2 . PHE B 1 468 ? 119.067 153.174 127.590 1.00 195.61 ?  468  PHE B CE2 1 
ATOM   6274 C CZ  . PHE B 1 468 ? 119.001 151.832 127.899 1.00 195.61 ?  468  PHE B CZ  1 
ATOM   6275 N N   . TRP B 1 469 ? 122.934 156.640 129.666 1.00 191.84 ?  469  TRP B N   1 
ATOM   6276 C CA  . TRP B 1 469 ? 123.502 157.596 128.724 1.00 191.84 ?  469  TRP B CA  1 
ATOM   6277 C C   . TRP B 1 469 ? 125.017 157.539 128.715 1.00 191.84 ?  469  TRP B C   1 
ATOM   6278 O O   . TRP B 1 469 ? 125.627 157.639 127.662 1.00 191.84 ?  469  TRP B O   1 
ATOM   6279 C CB  . TRP B 1 469 ? 122.980 159.026 128.944 1.00 191.84 ?  469  TRP B CB  1 
ATOM   6280 C CG  . TRP B 1 469 ? 123.414 159.722 130.200 1.00 191.84 ?  469  TRP B CG  1 
ATOM   6281 C CD1 . TRP B 1 469 ? 122.718 159.799 131.367 1.00 191.84 ?  469  TRP B CD1 1 
ATOM   6282 C CD2 . TRP B 1 469 ? 124.615 160.482 130.399 1.00 191.84 ?  469  TRP B CD2 1 
ATOM   6283 N NE1 . TRP B 1 469 ? 123.420 160.535 132.289 1.00 191.84 ?  469  TRP B NE1 1 
ATOM   6284 C CE2 . TRP B 1 469 ? 124.589 160.964 131.720 1.00 191.84 ?  469  TRP B CE2 1 
ATOM   6285 C CE3 . TRP B 1 469 ? 125.716 160.789 129.592 1.00 191.84 ?  469  TRP B CE3 1 
ATOM   6286 C CZ2 . TRP B 1 469 ? 125.616 161.738 132.252 1.00 191.84 ?  469  TRP B CZ2 1 
ATOM   6287 C CZ3 . TRP B 1 469 ? 126.736 161.551 130.124 1.00 191.84 ?  469  TRP B CZ3 1 
ATOM   6288 C CH2 . TRP B 1 469 ? 126.679 162.019 131.440 1.00 191.84 ?  469  TRP B CH2 1 
ATOM   6289 N N   . MET B 1 470 ? 125.625 157.357 129.879 1.00 169.44 ?  470  MET B N   1 
ATOM   6290 C CA  . MET B 1 470 ? 127.070 157.270 129.961 1.00 169.44 ?  470  MET B CA  1 
ATOM   6291 C C   . MET B 1 470 ? 127.584 156.148 129.087 1.00 169.44 ?  470  MET B C   1 
ATOM   6292 O O   . MET B 1 470 ? 128.502 156.345 128.304 1.00 169.44 ?  470  MET B O   1 
ATOM   6293 C CB  . MET B 1 470 ? 127.511 157.043 131.399 1.00 169.44 ?  470  MET B CB  1 
ATOM   6294 C CG  . MET B 1 470 ? 127.536 158.300 132.243 1.00 169.44 ?  470  MET B CG  1 
ATOM   6295 S SD  . MET B 1 470 ? 127.655 157.933 133.998 1.00 169.44 ?  470  MET B SD  1 
ATOM   6296 C CE  . MET B 1 470 ? 127.370 159.556 134.685 1.00 169.44 ?  470  MET B CE  1 
ATOM   6297 N N   . SER B 1 471 ? 126.988 154.969 129.208 1.00 148.38 ?  471  SER B N   1 
ATOM   6298 C CA  . SER B 1 471 ? 127.424 153.827 128.420 1.00 148.38 ?  471  SER B CA  1 
ATOM   6299 C C   . SER B 1 471 ? 127.192 154.042 126.934 1.00 148.38 ?  471  SER B C   1 
ATOM   6300 O O   . SER B 1 471 ? 128.020 153.663 126.118 1.00 148.38 ?  471  SER B O   1 
ATOM   6301 C CB  . SER B 1 471 ? 126.720 152.560 128.882 1.00 148.38 ?  471  SER B CB  1 
ATOM   6302 O OG  . SER B 1 471 ? 127.048 152.258 130.226 1.00 148.38 ?  471  SER B OG  1 
ATOM   6303 N N   . ILE B 1 472 ? 126.071 154.655 126.579 1.00 186.70 ?  472  ILE B N   1 
ATOM   6304 C CA  . ILE B 1 472 ? 125.769 154.912 125.178 1.00 186.70 ?  472  ILE B CA  1 
ATOM   6305 C C   . ILE B 1 472 ? 126.818 155.821 124.556 1.00 186.70 ?  472  ILE B C   1 
ATOM   6306 O O   . ILE B 1 472 ? 127.323 155.528 123.477 1.00 186.70 ?  472  ILE B O   1 
ATOM   6307 C CB  . ILE B 1 472 ? 124.348 155.498 125.009 1.00 186.70 ?  472  ILE B CB  1 
ATOM   6308 C CG1 . ILE B 1 472 ? 123.320 154.377 124.888 1.00 186.70 ?  472  ILE B CG1 1 
ATOM   6309 C CG2 . ILE B 1 472 ? 124.250 156.407 123.794 1.00 186.70 ?  472  ILE B CG2 1 
ATOM   6310 C CD1 . ILE B 1 472 ? 121.972 154.731 125.466 1.00 186.70 ?  472  ILE B CD1 1 
ATOM   6311 N N   . VAL B 1 473 ? 127.182 156.899 125.242 1.00 198.17 ?  473  VAL B N   1 
ATOM   6312 C CA  . VAL B 1 473 ? 128.131 157.856 124.675 1.00 198.17 ?  473  VAL B CA  1 
ATOM   6313 C C   . VAL B 1 473 ? 129.588 157.433 124.820 1.00 198.17 ?  473  VAL B C   1 
ATOM   6314 O O   . VAL B 1 473 ? 130.453 157.955 124.123 1.00 198.17 ?  473  VAL B O   1 
ATOM   6315 C CB  . VAL B 1 473 ? 127.920 159.280 125.231 1.00 198.17 ?  473  VAL B CB  1 
ATOM   6316 C CG1 . VAL B 1 473 ? 126.497 159.745 124.971 1.00 198.17 ?  473  VAL B CG1 1 
ATOM   6317 C CG2 . VAL B 1 473 ? 128.251 159.352 126.711 1.00 198.17 ?  473  VAL B CG2 1 
ATOM   6318 N N   . ALA B 1 474 ? 129.867 156.484 125.705 1.00 179.15 ?  474  ALA B N   1 
ATOM   6319 C CA  . ALA B 1 474 ? 131.228 155.989 125.866 1.00 179.15 ?  474  ALA B CA  1 
ATOM   6320 C C   . ALA B 1 474 ? 131.549 154.970 124.790 1.00 179.15 ?  474  ALA B C   1 
ATOM   6321 O O   . ALA B 1 474 ? 132.701 154.825 124.394 1.00 179.15 ?  474  ALA B O   1 
ATOM   6322 C CB  . ALA B 1 474 ? 131.412 155.383 127.241 1.00 179.15 ?  474  ALA B CB  1 
ATOM   6323 N N   . THR B 1 475 ? 130.528 154.271 124.311 1.00 160.89 ?  475  THR B N   1 
ATOM   6324 C CA  . THR B 1 475 ? 130.723 153.295 123.250 1.00 160.89 ?  475  THR B CA  1 
ATOM   6325 C C   . THR B 1 475 ? 130.731 153.991 121.897 1.00 160.89 ?  475  THR B C   1 
ATOM   6326 O O   . THR B 1 475 ? 130.863 153.339 120.866 1.00 160.89 ?  475  THR B O   1 
ATOM   6327 C CB  . THR B 1 475 ? 129.635 152.215 123.295 1.00 160.89 ?  475  THR B CB  1 
ATOM   6328 O OG1 . THR B 1 475 ? 128.345 152.836 123.304 1.00 160.89 ?  475  THR B OG1 1 
ATOM   6329 C CG2 . THR B 1 475 ? 129.779 151.388 124.549 1.00 160.89 ?  475  THR B CG2 1 
ATOM   6330 N N   . THR B 1 476 ? 130.596 155.312 121.894 1.00 196.92 ?  476  THR B N   1 
ATOM   6331 C CA  . THR B 1 476 ? 130.641 156.078 120.660 1.00 196.92 ?  476  THR B CA  1 
ATOM   6332 C C   . THR B 1 476 ? 132.007 156.729 120.510 1.00 196.92 ?  476  THR B C   1 
ATOM   6333 O O   . THR B 1 476 ? 132.367 157.197 119.431 1.00 196.92 ?  476  THR B O   1 
ATOM   6334 C CB  . THR B 1 476 ? 129.552 157.156 120.669 1.00 196.92 ?  476  THR B CB  1 
ATOM   6335 O OG1 . THR B 1 476 ? 128.359 156.608 121.236 1.00 196.92 ?  476  THR B OG1 1 
ATOM   6336 C CG2 . THR B 1 476 ? 129.248 157.640 119.265 1.00 196.92 ?  476  THR B CG2 1 
ATOM   6337 N N   . MET B 1 477 ? 132.787 156.744 121.585 1.00 192.79 ?  477  MET B N   1 
ATOM   6338 C CA  . MET B 1 477 ? 134.100 157.379 121.548 1.00 192.79 ?  477  MET B CA  1 
ATOM   6339 C C   . MET B 1 477 ? 135.054 156.655 120.610 1.00 192.79 ?  477  MET B C   1 
ATOM   6340 O O   . MET B 1 477 ? 134.934 155.446 120.422 1.00 192.79 ?  477  MET B O   1 
ATOM   6341 C CB  . MET B 1 477 ? 134.690 157.449 122.956 1.00 192.79 ?  477  MET B CB  1 
ATOM   6342 C CG  . MET B 1 477 ? 134.073 158.520 123.834 1.00 192.79 ?  477  MET B CG  1 
ATOM   6343 S SD  . MET B 1 477 ? 134.963 158.714 125.387 1.00 192.79 ?  477  MET B SD  1 
ATOM   6344 C CE  . MET B 1 477 ? 135.018 157.023 125.968 1.00 192.79 ?  477  MET B CE  1 
ATOM   6345 N N   . PRO B 1 478 ? 136.008 157.390 120.012 1.00 211.25 ?  478  PRO B N   1 
ATOM   6346 C CA  . PRO B 1 478 ? 136.990 156.785 119.101 1.00 211.25 ?  478  PRO B CA  1 
ATOM   6347 C C   . PRO B 1 478 ? 138.074 155.987 119.811 1.00 211.25 ?  478  PRO B C   1 
ATOM   6348 O O   . PRO B 1 478 ? 139.255 156.251 119.598 1.00 211.25 ?  478  PRO B O   1 
ATOM   6349 C CB  . PRO B 1 478 ? 137.617 157.999 118.418 1.00 211.25 ?  478  PRO B CB  1 
ATOM   6350 C CG  . PRO B 1 478 ? 137.428 159.118 119.379 1.00 211.25 ?  478  PRO B CG  1 
ATOM   6351 C CD  . PRO B 1 478 ? 136.103 158.860 120.028 1.00 211.25 ?  478  PRO B CD  1 
ATOM   6352 N N   . ILE B 1 479 ? 137.688 155.021 120.633 1.00 201.13 ?  479  ILE B N   1 
ATOM   6353 C CA  . ILE B 1 479 ? 138.641 154.214 121.372 1.00 201.13 ?  479  ILE B CA  1 
ATOM   6354 C C   . ILE B 1 479 ? 138.173 152.780 121.206 1.00 201.13 ?  479  ILE B C   1 
ATOM   6355 O O   . ILE B 1 479 ? 137.091 152.551 120.677 1.00 201.13 ?  479  ILE B O   1 
ATOM   6356 C CB  . ILE B 1 479 ? 138.625 154.594 122.867 1.00 201.13 ?  479  ILE B CB  1 
ATOM   6357 C CG1 . ILE B 1 479 ? 137.241 154.371 123.469 1.00 201.13 ?  479  ILE B CG1 1 
ATOM   6358 C CG2 . ILE B 1 479 ? 139.045 156.040 123.078 1.00 201.13 ?  479  ILE B CG2 1 
ATOM   6359 C CD1 . ILE B 1 479 ? 137.290 153.893 124.898 1.00 201.13 ?  479  ILE B CD1 1 
ATOM   6360 N N   . PRO B 1 480 ? 138.991 151.798 121.612 1.00 227.50 ?  480  PRO B N   1 
ATOM   6361 C CA  . PRO B 1 480 ? 138.479 150.426 121.556 1.00 227.50 ?  480  PRO B CA  1 
ATOM   6362 C C   . PRO B 1 480 ? 137.402 150.260 122.610 1.00 227.50 ?  480  PRO B C   1 
ATOM   6363 O O   . PRO B 1 480 ? 137.704 150.391 123.794 1.00 227.50 ?  480  PRO B O   1 
ATOM   6364 C CB  . PRO B 1 480 ? 139.694 149.584 121.928 1.00 227.50 ?  480  PRO B CB  1 
ATOM   6365 C CG  . PRO B 1 480 ? 140.862 150.423 121.576 1.00 227.50 ?  480  PRO B CG  1 
ATOM   6366 C CD  . PRO B 1 480 ? 140.439 151.831 121.866 1.00 227.50 ?  480  PRO B CD  1 
ATOM   6367 N N   . CYS B 1 481 ? 136.169 149.989 122.204 1.00 191.72 ?  481  CYS B N   1 
ATOM   6368 C CA  . CYS B 1 481 ? 135.079 149.901 123.166 1.00 191.72 ?  481  CYS B CA  1 
ATOM   6369 C C   . CYS B 1 481 ? 134.014 148.914 122.744 1.00 191.72 ?  481  CYS B C   1 
ATOM   6370 O O   . CYS B 1 481 ? 133.524 148.964 121.622 1.00 191.72 ?  481  CYS B O   1 
ATOM   6371 C CB  . CYS B 1 481 ? 134.445 151.278 123.384 1.00 191.72 ?  481  CYS B CB  1 
ATOM   6372 S SG  . CYS B 1 481 ? 134.098 152.208 121.876 1.00 191.72 ?  481  CYS B SG  1 
ATOM   6373 N N   . GLY B 1 482 ? 133.646 148.015 123.643 1.00 186.76 ?  482  GLY B N   1 
ATOM   6374 C CA  . GLY B 1 482 ? 132.597 147.060 123.347 1.00 186.76 ?  482  GLY B CA  1 
ATOM   6375 C C   . GLY B 1 482 ? 131.347 147.408 124.118 1.00 186.76 ?  482  GLY B C   1 
ATOM   6376 O O   . GLY B 1 482 ? 131.184 148.546 124.548 1.00 186.76 ?  482  GLY B O   1 
ATOM   6377 N N   . GLY B 1 483 ? 130.465 146.439 124.318 1.00 205.56 ?  483  GLY B N   1 
ATOM   6378 C CA  . GLY B 1 483 ? 129.209 146.741 124.974 1.00 205.56 ?  483  GLY B CA  1 
ATOM   6379 C C   . GLY B 1 483 ? 128.762 145.808 126.077 1.00 205.56 ?  483  GLY B C   1 
ATOM   6380 O O   . GLY B 1 483 ? 127.899 146.176 126.860 1.00 205.56 ?  483  GLY B O   1 
ATOM   6381 N N   . PHE B 1 484 ? 129.332 144.613 126.156 1.00 180.54 ?  484  PHE B N   1 
ATOM   6382 C CA  . PHE B 1 484 ? 128.878 143.645 127.147 1.00 180.54 ?  484  PHE B CA  1 
ATOM   6383 C C   . PHE B 1 484 ? 128.876 144.216 128.547 1.00 180.54 ?  484  PHE B C   1 
ATOM   6384 O O   . PHE B 1 484 ? 127.828 144.312 129.164 1.00 180.54 ?  484  PHE B O   1 
ATOM   6385 C CB  . PHE B 1 484 ? 129.732 142.386 127.124 1.00 180.54 ?  484  PHE B CB  1 
ATOM   6386 C CG  . PHE B 1 484 ? 129.052 141.177 127.700 1.00 180.54 ?  484  PHE B CG  1 
ATOM   6387 C CD1 . PHE B 1 484 ? 128.292 140.347 126.897 1.00 180.54 ?  484  PHE B CD1 1 
ATOM   6388 C CD2 . PHE B 1 484 ? 129.185 140.863 129.042 1.00 180.54 ?  484  PHE B CD2 1 
ATOM   6389 C CE1 . PHE B 1 484 ? 127.673 139.230 127.419 1.00 180.54 ?  484  PHE B CE1 1 
ATOM   6390 C CE2 . PHE B 1 484 ? 128.571 139.747 129.570 1.00 180.54 ?  484  PHE B CE2 1 
ATOM   6391 C CZ  . PHE B 1 484 ? 127.812 138.929 128.759 1.00 180.54 ?  484  PHE B CZ  1 
ATOM   6392 N N   . MET B 1 485 ? 130.044 144.584 129.059 1.00 207.53 ?  485  MET B N   1 
ATOM   6393 C CA  . MET B 1 485 ? 130.122 145.066 130.435 1.00 207.53 ?  485  MET B CA  1 
ATOM   6394 C C   . MET B 1 485 ? 129.295 146.313 130.738 1.00 207.53 ?  485  MET B C   1 
ATOM   6395 O O   . MET B 1 485 ? 128.610 146.349 131.748 1.00 207.53 ?  485  MET B O   1 
ATOM   6396 C CB  . MET B 1 485 ? 131.570 145.213 130.912 1.00 207.53 ?  485  MET B CB  1 
ATOM   6397 C CG  . MET B 1 485 ? 131.717 145.220 132.425 1.00 207.53 ?  485  MET B CG  1 
ATOM   6398 S SD  . MET B 1 485 ? 132.668 143.833 133.073 1.00 207.53 ?  485  MET B SD  1 
ATOM   6399 C CE  . MET B 1 485 ? 131.640 142.440 132.608 1.00 207.53 ?  485  MET B CE  1 
ATOM   6400 N N   . PRO B 1 486 ? 129.352 147.346 129.881 1.00 177.21 ?  486  PRO B N   1 
ATOM   6401 C CA  . PRO B 1 486 ? 128.470 148.475 130.185 1.00 177.21 ?  486  PRO B CA  1 
ATOM   6402 C C   . PRO B 1 486 ? 127.017 148.040 130.383 1.00 177.21 ?  486  PRO B C   1 
ATOM   6403 O O   . PRO B 1 486 ? 126.407 148.422 131.377 1.00 177.21 ?  486  PRO B O   1 
ATOM   6404 C CB  . PRO B 1 486 ? 128.599 149.346 128.943 1.00 177.21 ?  486  PRO B CB  1 
ATOM   6405 C CG  . PRO B 1 486 ? 129.982 149.107 128.470 1.00 177.21 ?  486  PRO B CG  1 
ATOM   6406 C CD  . PRO B 1 486 ? 130.313 147.684 128.813 1.00 177.21 ?  486  PRO B CD  1 
ATOM   6407 N N   . VAL B 1 487 ? 126.476 147.242 129.468 1.00 174.21 ?  487  VAL B N   1 
ATOM   6408 C CA  . VAL B 1 487 ? 125.089 146.791 129.566 1.00 174.21 ?  487  VAL B CA  1 
ATOM   6409 C C   . VAL B 1 487 ? 124.906 145.742 130.659 1.00 174.21 ?  487  VAL B C   1 
ATOM   6410 O O   . VAL B 1 487 ? 123.809 145.564 131.175 1.00 174.21 ?  487  VAL B O   1 
ATOM   6411 C CB  . VAL B 1 487 ? 124.582 146.283 128.202 1.00 174.21 ?  487  VAL B CB  1 
ATOM   6412 C CG1 . VAL B 1 487 ? 123.079 146.111 128.215 1.00 174.21 ?  487  VAL B CG1 1 
ATOM   6413 C CG2 . VAL B 1 487 ? 124.949 147.276 127.114 1.00 174.21 ?  487  VAL B CG2 1 
ATOM   6414 N N   . PHE B 1 488 ? 125.976 145.062 131.039 1.00 179.03 ?  488  PHE B N   1 
ATOM   6415 C CA  . PHE B 1 488 ? 125.905 144.090 132.122 1.00 179.03 ?  488  PHE B CA  1 
ATOM   6416 C C   . PHE B 1 488 ? 125.649 144.808 133.435 1.00 179.03 ?  488  PHE B C   1 
ATOM   6417 O O   . PHE B 1 488 ? 124.804 144.388 134.213 1.00 179.03 ?  488  PHE B O   1 
ATOM   6418 C CB  . PHE B 1 488 ? 127.216 143.324 132.213 1.00 179.03 ?  488  PHE B CB  1 
ATOM   6419 C CG  . PHE B 1 488 ? 127.086 141.943 132.770 1.00 179.03 ?  488  PHE B CG  1 
ATOM   6420 C CD1 . PHE B 1 488 ? 126.421 140.959 132.067 1.00 179.03 ?  488  PHE B CD1 1 
ATOM   6421 C CD2 . PHE B 1 488 ? 127.654 141.624 133.988 1.00 179.03 ?  488  PHE B CD2 1 
ATOM   6422 C CE1 . PHE B 1 488 ? 126.314 139.681 132.576 1.00 179.03 ?  488  PHE B CE1 1 
ATOM   6423 C CE2 . PHE B 1 488 ? 127.550 140.351 134.505 1.00 179.03 ?  488  PHE B CE2 1 
ATOM   6424 C CZ  . PHE B 1 488 ? 126.880 139.378 133.798 1.00 179.03 ?  488  PHE B CZ  1 
ATOM   6425 N N   . VAL B 1 489 ? 126.370 145.900 133.682 1.00 173.69 ?  489  VAL B N   1 
ATOM   6426 C CA  . VAL B 1 489 ? 126.149 146.671 134.902 1.00 173.69 ?  489  VAL B CA  1 
ATOM   6427 C C   . VAL B 1 489 ? 124.797 147.365 134.868 1.00 173.69 ?  489  VAL B C   1 
ATOM   6428 O O   . VAL B 1 489 ? 124.174 147.560 135.907 1.00 173.69 ?  489  VAL B O   1 
ATOM   6429 C CB  . VAL B 1 489 ? 127.292 147.671 135.218 1.00 173.69 ?  489  VAL B CB  1 
ATOM   6430 C CG1 . VAL B 1 489 ? 128.642 147.107 134.824 1.00 173.69 ?  489  VAL B CG1 1 
ATOM   6431 C CG2 . VAL B 1 489 ? 127.064 149.031 134.577 1.00 173.69 ?  489  VAL B CG2 1 
ATOM   6432 N N   . LEU B 1 490 ? 124.321 147.708 133.678 1.00 175.84 ?  490  LEU B N   1 
ATOM   6433 C CA  . LEU B 1 490 ? 123.027 148.353 133.553 1.00 175.84 ?  490  LEU B CA  1 
ATOM   6434 C C   . LEU B 1 490 ? 121.934 147.349 133.842 1.00 175.84 ?  490  LEU B C   1 
ATOM   6435 O O   . LEU B 1 490 ? 120.965 147.655 134.529 1.00 175.84 ?  490  LEU B O   1 
ATOM   6436 C CB  . LEU B 1 490 ? 122.855 148.927 132.153 1.00 175.84 ?  490  LEU B CB  1 
ATOM   6437 C CG  . LEU B 1 490 ? 123.568 150.251 131.928 1.00 175.84 ?  490  LEU B CG  1 
ATOM   6438 C CD1 . LEU B 1 490 ? 123.514 150.636 130.461 1.00 175.84 ?  490  LEU B CD1 1 
ATOM   6439 C CD2 . LEU B 1 490 ? 122.914 151.301 132.801 1.00 175.84 ?  490  LEU B CD2 1 
ATOM   6440 N N   . GLY B 1 491 ? 122.088 146.139 133.329 1.00 201.49 ?  491  GLY B N   1 
ATOM   6441 C CA  . GLY B 1 491 ? 121.109 145.108 133.582 1.00 201.49 ?  491  GLY B CA  1 
ATOM   6442 C C   . GLY B 1 491 ? 121.096 144.731 135.037 1.00 201.49 ?  491  GLY B C   1 
ATOM   6443 O O   . GLY B 1 491 ? 120.039 144.511 135.610 1.00 201.49 ?  491  GLY B O   1 
ATOM   6444 N N   . ALA B 1 492 ? 122.271 144.659 135.644 1.00 210.27 ?  492  ALA B N   1 
ATOM   6445 C CA  . ALA B 1 492 ? 122.360 144.316 137.049 1.00 210.27 ?  492  ALA B CA  1 
ATOM   6446 C C   . ALA B 1 492 ? 121.656 145.364 137.877 1.00 210.27 ?  492  ALA B C   1 
ATOM   6447 O O   . ALA B 1 492 ? 120.978 145.040 138.839 1.00 210.27 ?  492  ALA B O   1 
ATOM   6448 C CB  . ALA B 1 492 ? 123.810 144.189 137.466 1.00 210.27 ?  492  ALA B CB  1 
ATOM   6449 N N   . ALA B 1 493 ? 121.803 146.626 137.501 1.00 201.74 ?  493  ALA B N   1 
ATOM   6450 C CA  . ALA B 1 493 ? 121.140 147.698 138.219 1.00 201.74 ?  493  ALA B CA  1 
ATOM   6451 C C   . ALA B 1 493 ? 119.636 147.574 138.116 1.00 201.74 ?  493  ALA B C   1 
ATOM   6452 O O   . ALA B 1 493 ? 118.940 147.657 139.117 1.00 201.74 ?  493  ALA B O   1 
ATOM   6453 C CB  . ALA B 1 493 ? 121.590 149.037 137.686 1.00 201.74 ?  493  ALA B CB  1 
ATOM   6454 N N   . PHE B 1 494 ? 119.128 147.370 136.909 1.00 215.80 ?  494  PHE B N   1 
ATOM   6455 C CA  . PHE B 1 494 ? 117.694 147.203 136.727 1.00 215.80 ?  494  PHE B CA  1 
ATOM   6456 C C   . PHE B 1 494 ? 117.191 146.002 137.506 1.00 215.80 ?  494  PHE B C   1 
ATOM   6457 O O   . PHE B 1 494 ? 116.200 146.094 138.220 1.00 215.80 ?  494  PHE B O   1 
ATOM   6458 C CB  . PHE B 1 494 ? 117.342 147.052 135.251 1.00 215.80 ?  494  PHE B CB  1 
ATOM   6459 C CG  . PHE B 1 494 ? 115.870 147.044 134.988 1.00 215.80 ?  494  PHE B CG  1 
ATOM   6460 C CD1 . PHE B 1 494 ? 115.132 148.206 135.109 1.00 215.80 ?  494  PHE B CD1 1 
ATOM   6461 C CD2 . PHE B 1 494 ? 115.219 145.873 134.642 1.00 215.80 ?  494  PHE B CD2 1 
ATOM   6462 C CE1 . PHE B 1 494 ? 113.772 148.205 134.879 1.00 215.80 ?  494  PHE B CE1 1 
ATOM   6463 C CE2 . PHE B 1 494 ? 113.861 145.863 134.412 1.00 215.80 ?  494  PHE B CE2 1 
ATOM   6464 C CZ  . PHE B 1 494 ? 113.136 147.031 134.532 1.00 215.80 ?  494  PHE B CZ  1 
ATOM   6465 N N   . GLY B 1 495 ? 117.872 144.873 137.373 1.00 214.99 ?  495  GLY B N   1 
ATOM   6466 C CA  . GLY B 1 495 ? 117.482 143.686 138.099 1.00 214.99 ?  495  GLY B CA  1 
ATOM   6467 C C   . GLY B 1 495 ? 117.457 143.917 139.591 1.00 214.99 ?  495  GLY B C   1 
ATOM   6468 O O   . GLY B 1 495 ? 116.510 143.526 140.259 1.00 214.99 ?  495  GLY B O   1 
ATOM   6469 N N   . ARG B 1 496 ? 118.490 144.557 140.123 1.00 225.16 ?  496  ARG B N   1 
ATOM   6470 C CA  . ARG B 1 496 ? 118.551 144.823 141.551 1.00 225.16 ?  496  ARG B CA  1 
ATOM   6471 C C   . ARG B 1 496 ? 117.426 145.737 141.971 1.00 225.16 ?  496  ARG B C   1 
ATOM   6472 O O   . ARG B 1 496 ? 116.803 145.506 142.991 1.00 225.16 ?  496  ARG B O   1 
ATOM   6473 C CB  . ARG B 1 496 ? 119.889 145.437 141.941 1.00 225.16 ?  496  ARG B CB  1 
ATOM   6474 C CG  . ARG B 1 496 ? 120.107 145.550 143.436 1.00 225.16 ?  496  ARG B CG  1 
ATOM   6475 C CD  . ARG B 1 496 ? 120.774 144.306 143.984 1.00 225.16 ?  496  ARG B CD  1 
ATOM   6476 N NE  . ARG B 1 496 ? 120.719 144.262 145.438 1.00 225.16 ?  496  ARG B NE  1 
ATOM   6477 C CZ  . ARG B 1 496 ? 121.568 143.581 146.197 1.00 225.16 ?  496  ARG B CZ  1 
ATOM   6478 N NH1 . ARG B 1 496 ? 122.545 142.887 145.639 1.00 225.16 1  496  ARG B NH1 1 
ATOM   6479 N NH2 . ARG B 1 496 ? 121.441 143.598 147.513 1.00 225.16 ?  496  ARG B NH2 1 
ATOM   6480 N N   . LEU B 1 497 ? 117.155 146.772 141.189 1.00 207.47 ?  497  LEU B N   1 
ATOM   6481 C CA  . LEU B 1 497 ? 116.048 147.666 141.493 1.00 207.47 ?  497  LEU B CA  1 
ATOM   6482 C C   . LEU B 1 497 ? 114.777 146.857 141.651 1.00 207.47 ?  497  LEU B C   1 
ATOM   6483 O O   . LEU B 1 497 ? 114.094 146.976 142.660 1.00 207.47 ?  497  LEU B O   1 
ATOM   6484 C CB  . LEU B 1 497 ? 115.891 148.714 140.394 1.00 207.47 ?  497  LEU B CB  1 
ATOM   6485 C CG  . LEU B 1 497 ? 114.634 149.575 140.337 1.00 207.47 ?  497  LEU B CG  1 
ATOM   6486 C CD1 . LEU B 1 497 ? 114.976 151.005 140.709 1.00 207.47 ?  497  LEU B CD1 1 
ATOM   6487 C CD2 . LEU B 1 497 ? 114.035 149.517 138.942 1.00 207.47 ?  497  LEU B CD2 1 
ATOM   6488 N N   . VAL B 1 498 ? 114.467 146.014 140.671 1.00 210.38 ?  498  VAL B N   1 
ATOM   6489 C CA  . VAL B 1 498 ? 113.287 145.161 140.762 1.00 210.38 ?  498  VAL B CA  1 
ATOM   6490 C C   . VAL B 1 498 ? 113.332 144.305 142.017 1.00 210.38 ?  498  VAL B C   1 
ATOM   6491 O O   . VAL B 1 498 ? 112.372 144.270 142.771 1.00 210.38 ?  498  VAL B O   1 
ATOM   6492 C CB  . VAL B 1 498 ? 113.134 144.269 139.517 1.00 210.38 ?  498  VAL B CB  1 
ATOM   6493 C CG1 . VAL B 1 498 ? 111.955 143.320 139.671 1.00 210.38 ?  498  VAL B CG1 1 
ATOM   6494 C CG2 . VAL B 1 498 ? 112.962 145.128 138.275 1.00 210.38 ?  498  VAL B CG2 1 
ATOM   6495 N N   . GLY B 1 499 ? 114.451 143.636 142.259 1.00 215.52 ?  499  GLY B N   1 
ATOM   6496 C CA  . GLY B 1 499 ? 114.589 142.798 143.435 1.00 215.52 ?  499  GLY B CA  1 
ATOM   6497 C C   . GLY B 1 499 ? 114.436 143.515 144.756 1.00 215.52 ?  499  GLY B C   1 
ATOM   6498 O O   . GLY B 1 499 ? 113.905 142.948 145.703 1.00 215.52 ?  499  GLY B O   1 
ATOM   6499 N N   . GLU B 1 500 ? 114.898 144.756 144.835 1.00 232.84 ?  500  GLU B N   1 
ATOM   6500 C CA  . GLU B 1 500 ? 114.779 145.530 146.064 1.00 232.84 ?  500  GLU B CA  1 
ATOM   6501 C C   . GLU B 1 500 ? 113.352 145.991 146.255 1.00 232.84 ?  500  GLU B C   1 
ATOM   6502 O O   . GLU B 1 500 ? 112.876 146.086 147.381 1.00 232.84 ?  500  GLU B O   1 
ATOM   6503 C CB  . GLU B 1 500 ? 115.734 146.724 146.067 1.00 232.84 ?  500  GLU B CB  1 
ATOM   6504 C CG  . GLU B 1 500 ? 117.210 146.362 146.029 1.00 232.84 ?  500  GLU B CG  1 
ATOM   6505 C CD  . GLU B 1 500 ? 117.743 145.863 147.356 1.00 232.84 ?  500  GLU B CD  1 
ATOM   6506 O OE1 . GLU B 1 500 ? 117.025 145.949 148.370 1.00 232.84 ?  500  GLU B OE1 1 
ATOM   6507 O OE2 . GLU B 1 500 ? 118.892 145.380 147.385 1.00 232.84 -1 500  GLU B OE2 1 
ATOM   6508 N N   . ILE B 1 501 ? 112.659 146.278 145.161 1.00 224.81 ?  501  ILE B N   1 
ATOM   6509 C CA  . ILE B 1 501 ? 111.255 146.650 145.255 1.00 224.81 ?  501  ILE B CA  1 
ATOM   6510 C C   . ILE B 1 501 ? 110.466 145.410 145.645 1.00 224.81 ?  501  ILE B C   1 
ATOM   6511 O O   . ILE B 1 501 ? 109.522 145.493 146.417 1.00 224.81 ?  501  ILE B O   1 
ATOM   6512 C CB  . ILE B 1 501 ? 110.738 147.235 143.927 1.00 224.81 ?  501  ILE B CB  1 
ATOM   6513 C CG1 . ILE B 1 501 ? 111.417 148.571 143.636 1.00 224.81 ?  501  ILE B CG1 1 
ATOM   6514 C CG2 . ILE B 1 501 ? 109.231 147.434 143.956 1.00 224.81 ?  501  ILE B CG2 1 
ATOM   6515 C CD1 . ILE B 1 501 ? 111.198 149.063 142.223 1.00 224.81 ?  501  ILE B CD1 1 
ATOM   6516 N N   . MET B 1 502 ? 110.872 144.250 145.145 1.00 231.93 ?  502  MET B N   1 
ATOM   6517 C CA  . MET B 1 502 ? 110.202 143.006 145.499 1.00 231.93 ?  502  MET B CA  1 
ATOM   6518 C C   . MET B 1 502 ? 110.420 142.695 146.963 1.00 231.93 ?  502  MET B C   1 
ATOM   6519 O O   . MET B 1 502 ? 109.555 142.126 147.612 1.00 231.93 ?  502  MET B O   1 
ATOM   6520 C CB  . MET B 1 502 ? 110.715 141.852 144.643 1.00 231.93 ?  502  MET B CB  1 
ATOM   6521 C CG  . MET B 1 502 ? 110.153 141.816 143.234 1.00 231.93 ?  502  MET B CG  1 
ATOM   6522 S SD  . MET B 1 502 ? 108.436 141.284 143.199 1.00 231.93 ?  502  MET B SD  1 
ATOM   6523 C CE  . MET B 1 502 ? 108.620 139.526 143.484 1.00 231.93 ?  502  MET B CE  1 
ATOM   6524 N N   . ALA B 1 503 ? 111.573 143.074 147.493 1.00 224.20 ?  503  ALA B N   1 
ATOM   6525 C CA  . ALA B 1 503 ? 111.862 142.843 148.900 1.00 224.20 ?  503  ALA B CA  1 
ATOM   6526 C C   . ALA B 1 503 ? 111.138 143.856 149.760 1.00 224.20 ?  503  ALA B C   1 
ATOM   6527 O O   . ALA B 1 503 ? 110.984 143.656 150.959 1.00 224.20 ?  503  ALA B O   1 
ATOM   6528 C CB  . ALA B 1 503 ? 113.354 142.911 149.145 1.00 224.20 ?  503  ALA B CB  1 
ATOM   6529 N N   . MET B 1 504 ? 110.699 144.951 149.157 1.00 242.39 ?  504  MET B N   1 
ATOM   6530 C CA  . MET B 1 504 ? 109.951 145.956 149.890 1.00 242.39 ?  504  MET B CA  1 
ATOM   6531 C C   . MET B 1 504 ? 108.485 145.577 149.867 1.00 242.39 ?  504  MET B C   1 
ATOM   6532 O O   . MET B 1 504 ? 107.751 145.872 150.806 1.00 242.39 ?  504  MET B O   1 
ATOM   6533 C CB  . MET B 1 504 ? 110.141 147.325 149.246 1.00 242.39 ?  504  MET B CB  1 
ATOM   6534 C CG  . MET B 1 504 ? 110.487 148.438 150.218 1.00 242.39 ?  504  MET B CG  1 
ATOM   6535 S SD  . MET B 1 504 ? 110.886 149.976 149.366 1.00 242.39 ?  504  MET B SD  1 
ATOM   6536 C CE  . MET B 1 504 ? 110.586 149.507 147.666 1.00 242.39 ?  504  MET B CE  1 
ATOM   6537 N N   . LEU B 1 505 ? 108.055 144.919 148.797 1.00 248.74 ?  505  LEU B N   1 
ATOM   6538 C CA  . LEU B 1 505 ? 106.662 144.507 148.677 1.00 248.74 ?  505  LEU B CA  1 
ATOM   6539 C C   . LEU B 1 505 ? 106.443 143.230 149.452 1.00 248.74 ?  505  LEU B C   1 
ATOM   6540 O O   . LEU B 1 505 ? 105.368 143.012 150.004 1.00 248.74 ?  505  LEU B O   1 
ATOM   6541 C CB  . LEU B 1 505 ? 106.296 144.285 147.214 1.00 248.74 ?  505  LEU B CB  1 
ATOM   6542 C CG  . LEU B 1 505 ? 106.240 145.516 146.313 1.00 248.74 ?  505  LEU B CG  1 
ATOM   6543 C CD1 . LEU B 1 505 ? 106.062 145.094 144.864 1.00 248.74 ?  505  LEU B CD1 1 
ATOM   6544 C CD2 . LEU B 1 505 ? 105.128 146.454 146.750 1.00 248.74 ?  505  LEU B CD2 1 
ATOM   6545 N N   . PHE B 1 506 ? 107.457 142.376 149.491 1.00 246.98 ?  506  PHE B N   1 
ATOM   6546 C CA  . PHE B 1 506 ? 107.362 141.129 150.235 1.00 246.98 ?  506  PHE B CA  1 
ATOM   6547 C C   . PHE B 1 506 ? 108.484 141.071 151.253 1.00 246.98 ?  506  PHE B C   1 
ATOM   6548 O O   . PHE B 1 506 ? 109.502 140.426 151.017 1.00 246.98 ?  506  PHE B O   1 
ATOM   6549 C CB  . PHE B 1 506 ? 107.456 139.940 149.285 1.00 246.98 ?  506  PHE B CB  1 
ATOM   6550 C CG  . PHE B 1 506 ? 106.428 139.959 148.195 1.00 246.98 ?  506  PHE B CG  1 
ATOM   6551 C CD1 . PHE B 1 506 ? 105.096 139.725 148.483 1.00 246.98 ?  506  PHE B CD1 1 
ATOM   6552 C CD2 . PHE B 1 506 ? 106.790 140.222 146.887 1.00 246.98 ?  506  PHE B CD2 1 
ATOM   6553 C CE1 . PHE B 1 506 ? 104.143 139.747 147.484 1.00 246.98 ?  506  PHE B CE1 1 
ATOM   6554 C CE2 . PHE B 1 506 ? 105.843 140.247 145.884 1.00 246.98 ?  506  PHE B CE2 1 
ATOM   6555 C CZ  . PHE B 1 506 ? 104.518 140.008 146.182 1.00 246.98 ?  506  PHE B CZ  1 
ATOM   6556 N N   . PRO B 1 507 ? 108.305 141.743 152.399 1.00 253.49 ?  507  PRO B N   1 
ATOM   6557 C CA  . PRO B 1 507 ? 109.384 141.797 153.387 1.00 253.49 ?  507  PRO B CA  1 
ATOM   6558 C C   . PRO B 1 507 ? 109.610 140.470 154.096 1.00 253.49 ?  507  PRO B C   1 
ATOM   6559 O O   . PRO B 1 507 ? 110.718 140.215 154.562 1.00 253.49 ?  507  PRO B O   1 
ATOM   6560 C CB  . PRO B 1 507 ? 108.891 142.849 154.389 1.00 253.49 ?  507  PRO B CB  1 
ATOM   6561 C CG  . PRO B 1 507 ? 107.721 143.519 153.745 1.00 253.49 ?  507  PRO B CG  1 
ATOM   6562 C CD  . PRO B 1 507 ? 107.120 142.484 152.852 1.00 253.49 ?  507  PRO B CD  1 
ATOM   6563 N N   . ASP B 1 508 ? 108.582 139.635 154.176 1.00 263.43 ?  508  ASP B N   1 
ATOM   6564 C CA  . ASP B 1 508 ? 108.700 138.359 154.867 1.00 263.43 ?  508  ASP B CA  1 
ATOM   6565 C C   . ASP B 1 508 ? 108.849 137.206 153.891 1.00 263.43 ?  508  ASP B C   1 
ATOM   6566 O O   . ASP B 1 508 ? 108.885 136.047 154.297 1.00 263.43 ?  508  ASP B O   1 
ATOM   6567 C CB  . ASP B 1 508 ? 107.487 138.136 155.765 1.00 263.43 ?  508  ASP B CB  1 
ATOM   6568 C CG  . ASP B 1 508 ? 106.652 139.389 155.932 1.00 263.43 ?  508  ASP B CG  1 
ATOM   6569 O OD1 . ASP B 1 508 ? 106.956 140.190 156.840 1.00 263.43 ?  508  ASP B OD1 1 
ATOM   6570 O OD2 . ASP B 1 508 ? 105.695 139.576 155.151 1.00 263.43 -1 508  ASP B OD2 1 
ATOM   6571 N N   . GLY B 1 509 ? 108.936 137.516 152.604 1.00 262.92 ?  509  GLY B N   1 
ATOM   6572 C CA  . GLY B 1 509 ? 109.116 136.480 151.607 1.00 262.92 ?  509  GLY B CA  1 
ATOM   6573 C C   . GLY B 1 509 ? 107.818 136.070 150.954 1.00 262.92 ?  509  GLY B C   1 
ATOM   6574 O O   . GLY B 1 509 ? 106.755 136.576 151.305 1.00 262.92 ?  509  GLY B O   1 
ATOM   6575 N N   . ILE B 1 510 ? 107.896 135.157 149.994 1.00 274.31 ?  510  ILE B N   1 
ATOM   6576 C CA  . ILE B 1 510 ? 106.697 134.679 149.324 1.00 274.31 ?  510  ILE B CA  1 
ATOM   6577 C C   . ILE B 1 510 ? 106.554 133.175 149.476 1.00 274.31 ?  510  ILE B C   1 
ATOM   6578 O O   . ILE B 1 510 ? 107.402 132.418 149.011 1.00 274.31 ?  510  ILE B O   1 
ATOM   6579 C CB  . ILE B 1 510 ? 106.693 135.033 147.826 1.00 274.31 ?  510  ILE B CB  1 
ATOM   6580 C CG1 . ILE B 1 510 ? 108.029 135.633 147.400 1.00 274.31 ?  510  ILE B CG1 1 
ATOM   6581 C CG2 . ILE B 1 510 ? 105.568 136.004 147.513 1.00 274.31 ?  510  ILE B CG2 1 
ATOM   6582 C CD1 . ILE B 1 510 ? 107.940 136.400 146.101 1.00 274.31 ?  510  ILE B CD1 1 
ATOM   6583 N N   . LEU B 1 511 ? 105.480 132.739 150.123 1.00 278.35 ?  511  LEU B N   1 
ATOM   6584 C CA  . LEU B 1 511 ? 105.251 131.313 150.305 1.00 278.35 ?  511  LEU B CA  1 
ATOM   6585 C C   . LEU B 1 511 ? 104.783 130.652 149.021 1.00 278.35 ?  511  LEU B C   1 
ATOM   6586 O O   . LEU B 1 511 ? 103.913 131.176 148.329 1.00 278.35 ?  511  LEU B O   1 
ATOM   6587 C CB  . LEU B 1 511 ? 104.244 131.057 151.426 1.00 278.35 ?  511  LEU B CB  1 
ATOM   6588 C CG  . LEU B 1 511 ? 104.394 129.720 152.158 1.00 278.35 ?  511  LEU B CG  1 
ATOM   6589 C CD1 . LEU B 1 511 ? 104.420 129.930 153.662 1.00 278.35 ?  511  LEU B CD1 1 
ATOM   6590 C CD2 . LEU B 1 511 ? 103.285 128.754 151.773 1.00 278.35 ?  511  LEU B CD2 1 
ATOM   6591 N N   . PHE B 1 512 ? 105.357 129.501 148.702 1.00 288.57 ?  512  PHE B N   1 
ATOM   6592 C CA  . PHE B 1 512 ? 104.960 128.780 147.505 1.00 288.57 ?  512  PHE B CA  1 
ATOM   6593 C C   . PHE B 1 512 ? 104.132 127.574 147.905 1.00 288.57 ?  512  PHE B C   1 
ATOM   6594 O O   . PHE B 1 512 ? 102.940 127.698 148.180 1.00 288.57 ?  512  PHE B O   1 
ATOM   6595 C CB  . PHE B 1 512 ? 106.196 128.335 146.735 1.00 288.57 ?  512  PHE B CB  1 
ATOM   6596 C CG  . PHE B 1 512 ? 105.917 127.925 145.320 1.00 288.57 ?  512  PHE B CG  1 
ATOM   6597 C CD1 . PHE B 1 512 ? 104.751 128.316 144.686 1.00 288.57 ?  512  PHE B CD1 1 
ATOM   6598 C CD2 . PHE B 1 512 ? 106.823 127.144 144.627 1.00 288.57 ?  512  PHE B CD2 1 
ATOM   6599 C CE1 . PHE B 1 512 ? 104.492 127.933 143.388 1.00 288.57 ?  512  PHE B CE1 1 
ATOM   6600 C CE2 . PHE B 1 512 ? 106.570 126.757 143.328 1.00 288.57 ?  512  PHE B CE2 1 
ATOM   6601 C CZ  . PHE B 1 512 ? 105.402 127.150 142.710 1.00 288.57 ?  512  PHE B CZ  1 
ATOM   6602 N N   . ASP B 1 513 ? 104.754 126.402 147.935 1.00 309.02 ?  513  ASP B N   1 
ATOM   6603 C CA  . ASP B 1 513 ? 104.047 125.207 148.366 1.00 309.02 ?  513  ASP B CA  1 
ATOM   6604 C C   . ASP B 1 513 ? 104.046 125.183 149.877 1.00 309.02 ?  513  ASP B C   1 
ATOM   6605 O O   . ASP B 1 513 ? 102.999 125.326 150.504 1.00 309.02 ?  513  ASP B O   1 
ATOM   6606 C CB  . ASP B 1 513 ? 104.729 123.955 147.821 1.00 309.02 ?  513  ASP B CB  1 
ATOM   6607 C CG  . ASP B 1 513 ? 105.580 124.241 146.604 1.00 309.02 ?  513  ASP B CG  1 
ATOM   6608 O OD1 . ASP B 1 513 ? 105.019 124.294 145.490 1.00 309.02 ?  513  ASP B OD1 1 
ATOM   6609 O OD2 . ASP B 1 513 ? 106.807 124.411 146.760 1.00 309.02 -1 513  ASP B OD2 1 
ATOM   6610 N N   . ASP B 1 514 ? 105.219 125.008 150.468 1.00 319.74 ?  514  ASP B N   1 
ATOM   6611 C CA  . ASP B 1 514 ? 105.332 125.019 151.918 1.00 319.74 ?  514  ASP B CA  1 
ATOM   6612 C C   . ASP B 1 514 ? 106.601 125.758 152.263 1.00 319.74 ?  514  ASP B C   1 
ATOM   6613 O O   . ASP B 1 514 ? 107.093 125.671 153.387 1.00 319.74 ?  514  ASP B O   1 
ATOM   6614 C CB  . ASP B 1 514 ? 105.401 123.595 152.461 1.00 319.74 ?  514  ASP B CB  1 
ATOM   6615 C CG  . ASP B 1 514 ? 105.987 122.618 151.462 1.00 319.74 ?  514  ASP B CG  1 
ATOM   6616 O OD1 . ASP B 1 514 ? 107.224 122.611 151.288 1.00 319.74 ?  514  ASP B OD1 1 
ATOM   6617 O OD2 . ASP B 1 514 ? 105.210 121.857 150.848 1.00 319.74 -1 514  ASP B OD2 1 
ATOM   6618 N N   . ILE B 1 515 ? 107.142 126.487 151.295 1.00 292.48 ?  515  ILE B N   1 
ATOM   6619 C CA  . ILE B 1 515 ? 108.403 127.175 151.515 1.00 292.48 ?  515  ILE B CA  1 
ATOM   6620 C C   . ILE B 1 515 ? 108.270 128.679 151.383 1.00 292.48 ?  515  ILE B C   1 
ATOM   6621 O O   . ILE B 1 515 ? 107.806 129.171 150.360 1.00 292.48 ?  515  ILE B O   1 
ATOM   6622 C CB  . ILE B 1 515 ? 109.467 126.695 150.512 1.00 292.48 ?  515  ILE B CB  1 
ATOM   6623 C CG1 . ILE B 1 515 ? 108.861 125.682 149.538 1.00 292.48 ?  515  ILE B CG1 1 
ATOM   6624 C CG2 . ILE B 1 515 ? 110.658 126.098 151.244 1.00 292.48 ?  515  ILE B CG2 1 
ATOM   6625 C CD1 . ILE B 1 515 ? 109.735 124.474 149.289 1.00 292.48 ?  515  ILE B CD1 1 
ATOM   6626 N N   . ILE B 1 516 ? 108.681 129.414 152.410 1.00 282.09 ?  516  ILE B N   1 
ATOM   6627 C CA  . ILE B 1 516 ? 108.657 130.868 152.328 1.00 282.09 ?  516  ILE B CA  1 
ATOM   6628 C C   . ILE B 1 516 ? 109.927 131.353 151.662 1.00 282.09 ?  516  ILE B C   1 
ATOM   6629 O O   . ILE B 1 516 ? 110.921 131.622 152.332 1.00 282.09 ?  516  ILE B O   1 
ATOM   6630 C CB  . ILE B 1 516 ? 108.546 131.521 153.712 1.00 282.09 ?  516  ILE B CB  1 
ATOM   6631 C CG1 . ILE B 1 516 ? 108.136 130.483 154.757 1.00 282.09 ?  516  ILE B CG1 1 
ATOM   6632 C CG2 . ILE B 1 516 ? 107.558 132.676 153.673 1.00 282.09 ?  516  ILE B CG2 1 
ATOM   6633 C CD1 . ILE B 1 516 ? 107.578 131.086 156.027 1.00 282.09 ?  516  ILE B CD1 1 
ATOM   6634 N N   . TYR B 1 517 ? 109.901 131.461 150.341 1.00 286.12 ?  517  TYR B N   1 
ATOM   6635 C CA  . TYR B 1 517 ? 111.075 131.901 149.607 1.00 286.12 ?  517  TYR B CA  1 
ATOM   6636 C C   . TYR B 1 517 ? 111.371 133.359 149.890 1.00 286.12 ?  517  TYR B C   1 
ATOM   6637 O O   . TYR B 1 517 ? 110.557 134.226 149.591 1.00 286.12 ?  517  TYR B O   1 
ATOM   6638 C CB  . TYR B 1 517 ? 110.856 131.717 148.110 1.00 286.12 ?  517  TYR B CB  1 
ATOM   6639 C CG  . TYR B 1 517 ? 110.880 130.284 147.644 1.00 286.12 ?  517  TYR B CG  1 
ATOM   6640 C CD1 . TYR B 1 517 ? 112.070 129.673 147.283 1.00 286.12 ?  517  TYR B CD1 1 
ATOM   6641 C CD2 . TYR B 1 517 ? 109.711 129.547 147.550 1.00 286.12 ?  517  TYR B CD2 1 
ATOM   6642 C CE1 . TYR B 1 517 ? 112.095 128.364 146.847 1.00 286.12 ?  517  TYR B CE1 1 
ATOM   6643 C CE2 . TYR B 1 517 ? 109.727 128.241 147.113 1.00 286.12 ?  517  TYR B CE2 1 
ATOM   6644 C CZ  . TYR B 1 517 ? 110.921 127.655 146.766 1.00 286.12 ?  517  TYR B CZ  1 
ATOM   6645 O OH  . TYR B 1 517 ? 110.935 126.353 146.337 1.00 286.12 ?  517  TYR B OH  1 
ATOM   6646 N N   . LYS B 1 518 ? 112.538 133.637 150.454 1.00 248.57 ?  518  LYS B N   1 
ATOM   6647 C CA  . LYS B 1 518 ? 112.922 135.016 150.715 1.00 248.57 ?  518  LYS B CA  1 
ATOM   6648 C C   . LYS B 1 518 ? 113.466 135.658 149.452 1.00 248.57 ?  518  LYS B C   1 
ATOM   6649 O O   . LYS B 1 518 ? 114.101 134.992 148.637 1.00 248.57 ?  518  LYS B O   1 
ATOM   6650 C CB  . LYS B 1 518 ? 113.955 135.084 151.834 1.00 248.57 ?  518  LYS B CB  1 
ATOM   6651 C CG  . LYS B 1 518 ? 113.354 135.322 153.206 1.00 248.57 ?  518  LYS B CG  1 
ATOM   6652 C CD  . LYS B 1 518 ? 112.850 136.748 153.343 1.00 248.57 ?  518  LYS B CD  1 
ATOM   6653 C CE  . LYS B 1 518 ? 112.522 137.069 154.790 1.00 248.57 ?  518  LYS B CE  1 
ATOM   6654 N NZ  . LYS B 1 518 ? 111.843 135.924 155.456 1.00 248.57 1  518  LYS B NZ  1 
ATOM   6655 N N   . ILE B 1 519 ? 113.217 136.951 149.284 1.00 216.28 ?  519  ILE B N   1 
ATOM   6656 C CA  . ILE B 1 519 ? 113.670 137.649 148.087 1.00 216.28 ?  519  ILE B CA  1 
ATOM   6657 C C   . ILE B 1 519 ? 115.159 137.910 148.127 1.00 216.28 ?  519  ILE B C   1 
ATOM   6658 O O   . ILE B 1 519 ? 115.670 138.448 149.107 1.00 216.28 ?  519  ILE B O   1 
ATOM   6659 C CB  . ILE B 1 519 ? 112.943 138.991 147.915 1.00 216.28 ?  519  ILE B CB  1 
ATOM   6660 C CG1 . ILE B 1 519 ? 111.457 138.829 148.224 1.00 216.28 ?  519  ILE B CG1 1 
ATOM   6661 C CG2 . ILE B 1 519 ? 113.137 139.531 146.509 1.00 216.28 ?  519  ILE B CG2 1 
ATOM   6662 C CD1 . ILE B 1 519 ? 110.597 138.754 146.986 1.00 216.28 ?  519  ILE B CD1 1 
ATOM   6663 N N   . LEU B 1 520 ? 115.864 137.520 147.074 1.00 225.65 ?  520  LEU B N   1 
ATOM   6664 C CA  . LEU B 1 520 ? 117.290 137.787 146.995 1.00 225.65 ?  520  LEU B CA  1 
ATOM   6665 C C   . LEU B 1 520 ? 117.480 138.788 145.880 1.00 225.65 ?  520  LEU B C   1 
ATOM   6666 O O   . LEU B 1 520 ? 117.515 138.410 144.715 1.00 225.65 ?  520  LEU B O   1 
ATOM   6667 C CB  . LEU B 1 520 ? 118.051 136.506 146.674 1.00 225.65 ?  520  LEU B CB  1 
ATOM   6668 C CG  . LEU B 1 520 ? 119.492 136.377 147.166 1.00 225.65 ?  520  LEU B CG  1 
ATOM   6669 C CD1 . LEU B 1 520 ? 119.758 137.319 148.329 1.00 225.65 ?  520  LEU B CD1 1 
ATOM   6670 C CD2 . LEU B 1 520 ? 119.758 134.937 147.568 1.00 225.65 ?  520  LEU B CD2 1 
ATOM   6671 N N   . PRO B 1 521 ? 117.600 140.075 146.226 1.00 240.84 ?  521  PRO B N   1 
ATOM   6672 C CA  . PRO B 1 521 ? 117.705 141.104 145.192 1.00 240.84 ?  521  PRO B CA  1 
ATOM   6673 C C   . PRO B 1 521 ? 118.908 140.909 144.280 1.00 240.84 ?  521  PRO B C   1 
ATOM   6674 O O   . PRO B 1 521 ? 118.840 141.270 143.108 1.00 240.84 ?  521  PRO B O   1 
ATOM   6675 C CB  . PRO B 1 521 ? 117.849 142.385 146.003 1.00 240.84 ?  521  PRO B CB  1 
ATOM   6676 C CG  . PRO B 1 521 ? 117.228 142.078 147.320 1.00 240.84 ?  521  PRO B CG  1 
ATOM   6677 C CD  . PRO B 1 521 ? 117.607 140.655 147.577 1.00 240.84 ?  521  PRO B CD  1 
ATOM   6678 N N   . GLY B 1 522 ? 119.990 140.342 144.799 1.00 248.08 ?  522  GLY B N   1 
ATOM   6679 C CA  . GLY B 1 522 ? 121.170 140.098 143.995 1.00 248.08 ?  522  GLY B CA  1 
ATOM   6680 C C   . GLY B 1 522 ? 120.921 139.052 142.942 1.00 248.08 ?  522  GLY B C   1 
ATOM   6681 O O   . GLY B 1 522 ? 121.517 139.096 141.873 1.00 248.08 ?  522  GLY B O   1 
ATOM   6682 N N   . GLY B 1 523 ? 120.047 138.099 143.238 1.00 250.29 ?  523  GLY B N   1 
ATOM   6683 C CA  . GLY B 1 523 ? 119.702 137.087 142.262 1.00 250.29 ?  523  GLY B CA  1 
ATOM   6684 C C   . GLY B 1 523 ? 118.990 137.732 141.102 1.00 250.29 ?  523  GLY B C   1 
ATOM   6685 O O   . GLY B 1 523 ? 119.274 137.416 139.955 1.00 250.29 ?  523  GLY B O   1 
ATOM   6686 N N   . TYR B 1 524 ? 118.081 138.654 141.393 1.00 229.92 ?  524  TYR B N   1 
ATOM   6687 C CA  . TYR B 1 524 ? 117.371 139.368 140.345 1.00 229.92 ?  524  TYR B CA  1 
ATOM   6688 C C   . TYR B 1 524 ? 118.357 140.135 139.487 1.00 229.92 ?  524  TYR B C   1 
ATOM   6689 O O   . TYR B 1 524 ? 118.170 140.248 138.282 1.00 229.92 ?  524  TYR B O   1 
ATOM   6690 C CB  . TYR B 1 524 ? 116.371 140.343 140.957 1.00 229.92 ?  524  TYR B CB  1 
ATOM   6691 C CG  . TYR B 1 524 ? 115.102 139.717 141.481 1.00 229.92 ?  524  TYR B CG  1 
ATOM   6692 C CD1 . TYR B 1 524 ? 115.109 138.947 142.633 1.00 229.92 ?  524  TYR B CD1 1 
ATOM   6693 C CD2 . TYR B 1 524 ? 113.892 139.914 140.835 1.00 229.92 ?  524  TYR B CD2 1 
ATOM   6694 C CE1 . TYR B 1 524 ? 113.952 138.378 143.118 1.00 229.92 ?  524  TYR B CE1 1 
ATOM   6695 C CE2 . TYR B 1 524 ? 112.728 139.348 141.314 1.00 229.92 ?  524  TYR B CE2 1 
ATOM   6696 C CZ  . TYR B 1 524 ? 112.767 138.582 142.457 1.00 229.92 ?  524  TYR B CZ  1 
ATOM   6697 O OH  . TYR B 1 524 ? 111.616 138.015 142.942 1.00 229.92 ?  524  TYR B OH  1 
ATOM   6698 N N   . ALA B 1 525 ? 119.408 140.667 140.102 1.00 256.65 ?  525  ALA B N   1 
ATOM   6699 C CA  . ALA B 1 525 ? 120.422 141.409 139.364 1.00 256.65 ?  525  ALA B CA  1 
ATOM   6700 C C   . ALA B 1 525 ? 121.138 140.545 138.349 1.00 256.65 ?  525  ALA B C   1 
ATOM   6701 O O   . ALA B 1 525 ? 121.346 140.969 137.222 1.00 256.65 ?  525  ALA B O   1 
ATOM   6702 C CB  . ALA B 1 525 ? 121.417 142.028 140.318 1.00 256.65 ?  525  ALA B CB  1 
ATOM   6703 N N   . VAL B 1 526 ? 121.523 139.335 138.738 1.00 270.30 ?  526  VAL B N   1 
ATOM   6704 C CA  . VAL B 1 526 ? 122.164 138.419 137.801 1.00 270.30 ?  526  VAL B CA  1 
ATOM   6705 C C   . VAL B 1 526 ? 121.268 138.200 136.596 1.00 270.30 ?  526  VAL B C   1 
ATOM   6706 O O   . VAL B 1 526 ? 121.719 138.279 135.455 1.00 270.30 ?  526  VAL B O   1 
ATOM   6707 C CB  . VAL B 1 526 ? 122.491 137.068 138.460 1.00 270.30 ?  526  VAL B CB  1 
ATOM   6708 C CG1 . VAL B 1 526 ? 123.299 136.194 137.518 1.00 270.30 ?  526  VAL B CG1 1 
ATOM   6709 C CG2 . VAL B 1 526 ? 123.250 137.281 139.756 1.00 270.30 ?  526  VAL B CG2 1 
ATOM   6710 N N   . ILE B 1 527 ? 119.989 137.944 136.843 1.00 254.86 ?  527  ILE B N   1 
ATOM   6711 C CA  . ILE B 1 527 ? 119.044 137.730 135.755 1.00 254.86 ?  527  ILE B CA  1 
ATOM   6712 C C   . ILE B 1 527 ? 118.927 138.966 134.880 1.00 254.86 ?  527  ILE B C   1 
ATOM   6713 O O   . ILE B 1 527 ? 118.959 138.863 133.659 1.00 254.86 ?  527  ILE B O   1 
ATOM   6714 C CB  . ILE B 1 527 ? 117.659 137.351 136.301 1.00 254.86 ?  527  ILE B CB  1 
ATOM   6715 C CG1 . ILE B 1 527 ? 117.802 136.382 137.467 1.00 254.86 ?  527  ILE B CG1 1 
ATOM   6716 C CG2 . ILE B 1 527 ? 116.802 136.729 135.219 1.00 254.86 ?  527  ILE B CG2 1 
ATOM   6717 C CD1 . ILE B 1 527 ? 117.354 134.978 137.158 1.00 254.86 ?  527  ILE B CD1 1 
ATOM   6718 N N   . GLY B 1 528 ? 118.803 140.135 135.495 1.00 250.40 ?  528  GLY B N   1 
ATOM   6719 C CA  . GLY B 1 528 ? 118.696 141.369 134.742 1.00 250.40 ?  528  GLY B CA  1 
ATOM   6720 C C   . GLY B 1 528 ? 119.906 141.630 133.883 1.00 250.40 ?  528  GLY B C   1 
ATOM   6721 O O   . GLY B 1 528 ? 119.775 142.103 132.760 1.00 250.40 ?  528  GLY B O   1 
ATOM   6722 N N   . ALA B 1 529 ? 121.090 141.331 134.401 1.00 232.85 ?  529  ALA B N   1 
ATOM   6723 C CA  . ALA B 1 529 ? 122.317 141.523 133.645 1.00 232.85 ?  529  ALA B CA  1 
ATOM   6724 C C   . ALA B 1 529 ? 122.269 140.685 132.398 1.00 232.85 ?  529  ALA B C   1 
ATOM   6725 O O   . ALA B 1 529 ? 122.440 141.201 131.302 1.00 232.85 ?  529  ALA B O   1 
ATOM   6726 C CB  . ALA B 1 529 ? 123.512 141.141 134.490 1.00 232.85 ?  529  ALA B CB  1 
ATOM   6727 N N   . ALA B 1 530 ? 122.006 139.394 132.557 1.00 253.14 ?  530  ALA B N   1 
ATOM   6728 C CA  . ALA B 1 530 ? 121.917 138.494 131.418 1.00 253.14 ?  530  ALA B CA  1 
ATOM   6729 C C   . ALA B 1 530 ? 120.846 138.907 130.428 1.00 253.14 ?  530  ALA B C   1 
ATOM   6730 O O   . ALA B 1 530 ? 121.019 138.749 129.226 1.00 253.14 ?  530  ALA B O   1 
ATOM   6731 C CB  . ALA B 1 530 ? 121.650 137.087 131.901 1.00 253.14 ?  530  ALA B CB  1 
ATOM   6732 N N   . ALA B 1 531 ? 119.734 139.429 130.924 1.00 261.07 ?  531  ALA B N   1 
ATOM   6733 C CA  . ALA B 1 531 ? 118.641 139.815 130.048 1.00 261.07 ?  531  ALA B CA  1 
ATOM   6734 C C   . ALA B 1 531 ? 118.966 141.038 129.205 1.00 261.07 ?  531  ALA B C   1 
ATOM   6735 O O   . ALA B 1 531 ? 118.749 141.023 128.001 1.00 261.07 ?  531  ALA B O   1 
ATOM   6736 C CB  . ALA B 1 531 ? 117.373 140.033 130.850 1.00 261.07 ?  531  ALA B CB  1 
ATOM   6737 N N   . LEU B 1 532 ? 119.488 142.096 129.818 1.00 256.25 ?  532  LEU B N   1 
ATOM   6738 C CA  . LEU B 1 532 ? 119.755 143.320 129.070 1.00 256.25 ?  532  LEU B CA  1 
ATOM   6739 C C   . LEU B 1 532 ? 120.924 143.136 128.128 1.00 256.25 ?  532  LEU B C   1 
ATOM   6740 O O   . LEU B 1 532 ? 120.921 143.663 127.022 1.00 256.25 ?  532  LEU B O   1 
ATOM   6741 C CB  . LEU B 1 532 ? 120.004 144.515 129.993 1.00 256.25 ?  532  LEU B CB  1 
ATOM   6742 C CG  . LEU B 1 532 ? 119.101 145.735 129.777 1.00 256.25 ?  532  LEU B CG  1 
ATOM   6743 C CD1 . LEU B 1 532 ? 119.009 146.606 131.018 1.00 256.25 ?  532  LEU B CD1 1 
ATOM   6744 C CD2 . LEU B 1 532 ? 119.534 146.567 128.586 1.00 256.25 ?  532  LEU B CD2 1 
ATOM   6745 N N   . THR B 1 533 ? 121.923 142.377 128.556 1.00 240.29 ?  533  THR B N   1 
ATOM   6746 C CA  . THR B 1 533 ? 123.079 142.134 127.709 1.00 240.29 ?  533  THR B CA  1 
ATOM   6747 C C   . THR B 1 533 ? 122.758 141.099 126.645 1.00 240.29 ?  533  THR B C   1 
ATOM   6748 O O   . THR B 1 533 ? 123.512 140.940 125.694 1.00 240.29 ?  533  THR B O   1 
ATOM   6749 C CB  . THR B 1 533 ? 124.332 141.765 128.532 1.00 240.29 ?  533  THR B CB  1 
ATOM   6750 O OG1 . THR B 1 533 ? 125.509 142.078 127.779 1.00 240.29 ?  533  THR B OG1 1 
ATOM   6751 C CG2 . THR B 1 533 ? 124.343 140.304 128.893 1.00 240.29 ?  533  THR B CG2 1 
ATOM   6752 N N   . GLY B 1 534 ? 121.630 140.413 126.782 1.00 242.01 ?  534  GLY B N   1 
ATOM   6753 C CA  . GLY B 1 534 ? 121.212 139.452 125.779 1.00 242.01 ?  534  GLY B CA  1 
ATOM   6754 C C   . GLY B 1 534 ? 120.222 140.092 124.840 1.00 242.01 ?  534  GLY B C   1 
ATOM   6755 O O   . GLY B 1 534 ? 119.945 139.561 123.776 1.00 242.01 ?  534  GLY B O   1 
ATOM   6756 N N   . ALA B 1 535 ? 119.677 141.234 125.228 1.00 218.20 ?  535  ALA B N   1 
ATOM   6757 C CA  . ALA B 1 535 ? 118.756 141.956 124.370 1.00 218.20 ?  535  ALA B CA  1 
ATOM   6758 C C   . ALA B 1 535 ? 119.555 142.886 123.487 1.00 218.20 ?  535  ALA B C   1 
ATOM   6759 O O   . ALA B 1 535 ? 119.173 143.164 122.358 1.00 218.20 ?  535  ALA B O   1 
ATOM   6760 C CB  . ALA B 1 535 ? 117.790 142.755 125.214 1.00 218.20 ?  535  ALA B CB  1 
ATOM   6761 N N   . VAL B 1 536 ? 120.669 143.380 124.003 1.00 228.69 ?  536  VAL B N   1 
ATOM   6762 C CA  . VAL B 1 536 ? 121.513 144.275 123.231 1.00 228.69 ?  536  VAL B CA  1 
ATOM   6763 C C   . VAL B 1 536 ? 122.292 143.474 122.199 1.00 228.69 ?  536  VAL B C   1 
ATOM   6764 O O   . VAL B 1 536 ? 122.444 143.905 121.059 1.00 228.69 ?  536  VAL B O   1 
ATOM   6765 C CB  . VAL B 1 536 ? 122.439 145.087 124.163 1.00 228.69 ?  536  VAL B CB  1 
ATOM   6766 C CG1 . VAL B 1 536 ? 123.823 145.286 123.567 1.00 228.69 ?  536  VAL B CG1 1 
ATOM   6767 C CG2 . VAL B 1 536 ? 121.803 146.421 124.507 1.00 228.69 ?  536  VAL B CG2 1 
ATOM   6768 N N   . SER B 1 537 ? 122.746 142.284 122.575 1.00 244.47 ?  537  SER B N   1 
ATOM   6769 C CA  . SER B 1 537 ? 123.538 141.468 121.667 1.00 244.47 ?  537  SER B CA  1 
ATOM   6770 C C   . SER B 1 537 ? 122.706 140.431 120.945 1.00 244.47 ?  537  SER B C   1 
ATOM   6771 O O   . SER B 1 537 ? 123.242 139.678 120.137 1.00 244.47 ?  537  SER B O   1 
ATOM   6772 C CB  . SER B 1 537 ? 124.645 140.769 122.438 1.00 244.47 ?  537  SER B CB  1 
ATOM   6773 O OG  . SER B 1 537 ? 124.105 139.828 123.339 1.00 244.47 ?  537  SER B OG  1 
ATOM   6774 N N   . HIS B 1 538 ? 121.408 140.385 121.228 1.00 246.50 ?  538  HIS B N   1 
ATOM   6775 C CA  . HIS B 1 538 ? 120.514 139.402 120.612 1.00 246.50 ?  538  HIS B CA  1 
ATOM   6776 C C   . HIS B 1 538 ? 121.012 137.980 120.799 1.00 246.50 ?  538  HIS B C   1 
ATOM   6777 O O   . HIS B 1 538 ? 120.990 137.186 119.864 1.00 246.50 ?  538  HIS B O   1 
ATOM   6778 C CB  . HIS B 1 538 ? 120.273 139.706 119.135 1.00 246.50 ?  538  HIS B CB  1 
ATOM   6779 C CG  . HIS B 1 538 ? 119.315 140.829 118.898 1.00 246.50 ?  538  HIS B CG  1 
ATOM   6780 N ND1 . HIS B 1 538 ? 118.938 141.229 117.635 1.00 246.50 ?  538  HIS B ND1 1 
ATOM   6781 C CD2 . HIS B 1 538 ? 118.658 141.637 119.761 1.00 246.50 ?  538  HIS B CD2 1 
ATOM   6782 C CE1 . HIS B 1 538 ? 118.089 142.236 117.732 1.00 246.50 ?  538  HIS B CE1 1 
ATOM   6783 N NE2 . HIS B 1 538 ? 117.905 142.506 119.011 1.00 246.50 ?  538  HIS B NE2 1 
ATOM   6784 N N   . THR B 1 539 ? 121.453 137.650 122.009 1.00 247.03 ?  539  THR B N   1 
ATOM   6785 C CA  . THR B 1 539 ? 121.937 136.308 122.293 1.00 247.03 ?  539  THR B CA  1 
ATOM   6786 C C   . THR B 1 539 ? 121.278 135.739 123.524 1.00 247.03 ?  539  THR B C   1 
ATOM   6787 O O   . THR B 1 539 ? 120.877 136.475 124.416 1.00 247.03 ?  539  THR B O   1 
ATOM   6788 C CB  . THR B 1 539 ? 123.445 136.286 122.562 1.00 247.03 ?  539  THR B CB  1 
ATOM   6789 O OG1 . THR B 1 539 ? 123.755 137.219 123.599 1.00 247.03 ?  539  THR B OG1 1 
ATOM   6790 C CG2 . THR B 1 539 ? 124.213 136.636 121.322 1.00 247.03 ?  539  THR B CG2 1 
ATOM   6791 N N   . VAL B 1 540 ? 121.179 134.420 123.584 1.00 231.76 ?  540  VAL B N   1 
ATOM   6792 C CA  . VAL B 1 540 ? 120.586 133.774 124.738 1.00 231.76 ?  540  VAL B CA  1 
ATOM   6793 C C   . VAL B 1 540 ? 121.671 133.027 125.489 1.00 231.76 ?  540  VAL B C   1 
ATOM   6794 O O   . VAL B 1 540 ? 121.389 132.301 126.438 1.00 231.76 ?  540  VAL B O   1 
ATOM   6795 C CB  . VAL B 1 540 ? 119.479 132.800 124.309 1.00 231.76 ?  540  VAL B CB  1 
ATOM   6796 C CG1 . VAL B 1 540 ? 118.138 133.514 124.259 1.00 231.76 ?  540  VAL B CG1 1 
ATOM   6797 C CG2 . VAL B 1 540 ? 119.807 132.188 122.957 1.00 231.76 ?  540  VAL B CG2 1 
ATOM   6798 N N   . SER B 1 541 ? 122.919 133.211 125.072 1.00 248.46 ?  541  SER B N   1 
ATOM   6799 C CA  . SER B 1 541 ? 124.036 132.526 125.710 1.00 248.46 ?  541  SER B CA  1 
ATOM   6800 C C   . SER B 1 541 ? 124.538 133.319 126.887 1.00 248.46 ?  541  SER B C   1 
ATOM   6801 O O   . SER B 1 541 ? 125.439 132.881 127.597 1.00 248.46 ?  541  SER B O   1 
ATOM   6802 C CB  . SER B 1 541 ? 125.165 132.346 124.714 1.00 248.46 ?  541  SER B CB  1 
ATOM   6803 O OG  . SER B 1 541 ? 125.180 133.417 123.792 1.00 248.46 ?  541  SER B OG  1 
ATOM   6804 N N   . THR B 1 542 ? 123.959 134.491 127.102 1.00 250.86 ?  542  THR B N   1 
ATOM   6805 C CA  . THR B 1 542 ? 124.346 135.317 128.230 1.00 250.86 ?  542  THR B CA  1 
ATOM   6806 C C   . THR B 1 542 ? 123.891 134.657 129.508 1.00 250.86 ?  542  THR B C   1 
ATOM   6807 O O   . THR B 1 542 ? 124.484 134.869 130.561 1.00 250.86 ?  542  THR B O   1 
ATOM   6808 C CB  . THR B 1 542 ? 123.733 136.708 128.106 1.00 250.86 ?  542  THR B CB  1 
ATOM   6809 O OG1 . THR B 1 542 ? 122.308 136.592 128.033 1.00 250.86 ?  542  THR B OG1 1 
ATOM   6810 C CG2 . THR B 1 542 ? 124.238 137.371 126.847 1.00 250.86 ?  542  THR B CG2 1 
ATOM   6811 N N   . ALA B 1 543 ? 122.842 133.848 129.426 1.00 235.53 ?  543  ALA B N   1 
ATOM   6812 C CA  . ALA B 1 543 ? 122.387 133.110 130.589 1.00 235.53 ?  543  ALA B CA  1 
ATOM   6813 C C   . ALA B 1 543 ? 123.486 132.166 131.028 1.00 235.53 ?  543  ALA B C   1 
ATOM   6814 O O   . ALA B 1 543 ? 123.807 132.103 132.205 1.00 235.53 ?  543  ALA B O   1 
ATOM   6815 C CB  . ALA B 1 543 ? 121.126 132.337 130.261 1.00 235.53 ?  543  ALA B CB  1 
ATOM   6816 N N   . VAL B 1 544 ? 124.076 131.441 130.084 1.00 243.13 ?  544  VAL B N   1 
ATOM   6817 C CA  . VAL B 1 544 ? 125.156 130.510 130.406 1.00 243.13 ?  544  VAL B CA  1 
ATOM   6818 C C   . VAL B 1 544 ? 126.384 131.224 130.943 1.00 243.13 ?  544  VAL B C   1 
ATOM   6819 O O   . VAL B 1 544 ? 127.033 130.732 131.864 1.00 243.13 ?  544  VAL B O   1 
ATOM   6820 C CB  . VAL B 1 544 ? 125.551 129.657 129.191 1.00 243.13 ?  544  VAL B CB  1 
ATOM   6821 C CG1 . VAL B 1 544 ? 126.034 128.291 129.645 1.00 243.13 ?  544  VAL B CG1 1 
ATOM   6822 C CG2 . VAL B 1 544 ? 124.373 129.515 128.242 1.00 243.13 ?  544  VAL B CG2 1 
ATOM   6823 N N   . ILE B 1 545 ? 126.712 132.380 130.377 1.00 258.02 ?  545  ILE B N   1 
ATOM   6824 C CA  . ILE B 1 545 ? 127.834 133.155 130.888 1.00 258.02 ?  545  ILE B CA  1 
ATOM   6825 C C   . ILE B 1 545 ? 127.570 133.465 132.349 1.00 258.02 ?  545  ILE B C   1 
ATOM   6826 O O   . ILE B 1 545 ? 128.439 133.275 133.196 1.00 258.02 ?  545  ILE B O   1 
ATOM   6827 C CB  . ILE B 1 545 ? 128.030 134.461 130.097 1.00 258.02 ?  545  ILE B CB  1 
ATOM   6828 C CG1 . ILE B 1 545 ? 128.520 134.157 128.684 1.00 258.02 ?  545  ILE B CG1 1 
ATOM   6829 C CG2 . ILE B 1 545 ? 129.011 135.387 130.800 1.00 258.02 ?  545  ILE B CG2 1 
ATOM   6830 C CD1 . ILE B 1 545 ? 128.091 135.180 127.659 1.00 258.02 ?  545  ILE B CD1 1 
ATOM   6831 N N   . CYS B 1 546 ? 126.359 133.909 132.654 1.00 261.36 ?  546  CYS B N   1 
ATOM   6832 C CA  . CYS B 1 546 ? 126.006 134.233 134.026 1.00 261.36 ?  546  CYS B CA  1 
ATOM   6833 C C   . CYS B 1 546 ? 126.018 133.012 134.930 1.00 261.36 ?  546  CYS B C   1 
ATOM   6834 O O   . CYS B 1 546 ? 126.479 133.091 136.058 1.00 261.36 ?  546  CYS B O   1 
ATOM   6835 C CB  . CYS B 1 546 ? 124.638 134.899 134.074 1.00 261.36 ?  546  CYS B CB  1 
ATOM   6836 S SG  . CYS B 1 546 ? 124.681 136.697 133.974 1.00 261.36 ?  546  CYS B SG  1 
ATOM   6837 N N   . PHE B 1 547 ? 125.518 131.882 134.442 1.00 243.82 ?  547  PHE B N   1 
ATOM   6838 C CA  . PHE B 1 547 ? 125.504 130.657 135.237 1.00 243.82 ?  547  PHE B CA  1 
ATOM   6839 C C   . PHE B 1 547 ? 126.902 130.292 135.688 1.00 243.82 ?  547  PHE B C   1 
ATOM   6840 O O   . PHE B 1 547 ? 127.106 129.891 136.827 1.00 243.82 ?  547  PHE B O   1 
ATOM   6841 C CB  . PHE B 1 547 ? 124.944 129.490 134.431 1.00 243.82 ?  547  PHE B CB  1 
ATOM   6842 C CG  . PHE B 1 547 ? 123.484 129.601 134.130 1.00 243.82 ?  547  PHE B CG  1 
ATOM   6843 C CD1 . PHE B 1 547 ? 122.629 130.254 134.996 1.00 243.82 ?  547  PHE B CD1 1 
ATOM   6844 C CD2 . PHE B 1 547 ? 122.966 129.044 132.974 1.00 243.82 ?  547  PHE B CD2 1 
ATOM   6845 C CE1 . PHE B 1 547 ? 121.284 130.355 134.711 1.00 243.82 ?  547  PHE B CE1 1 
ATOM   6846 C CE2 . PHE B 1 547 ? 121.623 129.145 132.681 1.00 243.82 ?  547  PHE B CE2 1 
ATOM   6847 C CZ  . PHE B 1 547 ? 120.782 129.805 133.549 1.00 243.82 ?  547  PHE B CZ  1 
ATOM   6848 N N   . GLU B 1 548 ? 127.870 130.416 134.790 1.00 251.54 ?  548  GLU B N   1 
ATOM   6849 C CA  . GLU B 1 548 ? 129.237 130.051 135.121 1.00 251.54 ?  548  GLU B CA  1 
ATOM   6850 C C   . GLU B 1 548 ? 129.916 131.105 135.971 1.00 251.54 ?  548  GLU B C   1 
ATOM   6851 O O   . GLU B 1 548 ? 130.801 130.792 136.759 1.00 251.54 ?  548  GLU B O   1 
ATOM   6852 C CB  . GLU B 1 548 ? 130.040 129.804 133.850 1.00 251.54 ?  548  GLU B CB  1 
ATOM   6853 C CG  . GLU B 1 548 ? 129.934 128.382 133.331 1.00 251.54 ?  548  GLU B CG  1 
ATOM   6854 C CD  . GLU B 1 548 ? 130.271 128.278 131.860 1.00 251.54 ?  548  GLU B CD  1 
ATOM   6855 O OE1 . GLU B 1 548 ? 129.360 128.468 131.028 1.00 251.54 ?  548  GLU B OE1 1 
ATOM   6856 O OE2 . GLU B 1 548 ? 131.449 128.015 131.537 1.00 251.54 -1 548  GLU B OE2 1 
ATOM   6857 N N   . LEU B 1 549 ? 129.505 132.356 135.819 1.00 243.78 ?  549  LEU B N   1 
ATOM   6858 C CA  . LEU B 1 549 ? 130.079 133.428 136.618 1.00 243.78 ?  549  LEU B CA  1 
ATOM   6859 C C   . LEU B 1 549 ? 129.511 133.396 138.024 1.00 243.78 ?  549  LEU B C   1 
ATOM   6860 O O   . LEU B 1 549 ? 130.132 133.896 138.956 1.00 243.78 ?  549  LEU B O   1 
ATOM   6861 C CB  . LEU B 1 549 ? 129.800 134.784 135.972 1.00 243.78 ?  549  LEU B CB  1 
ATOM   6862 C CG  . LEU B 1 549 ? 130.868 135.299 135.011 1.00 243.78 ?  549  LEU B CG  1 
ATOM   6863 C CD1 . LEU B 1 549 ? 130.491 136.669 134.470 1.00 243.78 ?  549  LEU B CD1 1 
ATOM   6864 C CD2 . LEU B 1 549 ? 132.217 135.346 135.707 1.00 243.78 ?  549  LEU B CD2 1 
ATOM   6865 N N   . THR B 1 550 ? 128.329 132.814 138.182 1.00 250.34 ?  550  THR B N   1 
ATOM   6866 C CA  . THR B 1 550 ? 127.683 132.761 139.484 1.00 250.34 ?  550  THR B CA  1 
ATOM   6867 C C   . THR B 1 550 ? 127.355 131.321 139.838 1.00 250.34 ?  550  THR B C   1 
ATOM   6868 O O   . THR B 1 550 ? 128.163 130.425 139.597 1.00 250.34 ?  550  THR B O   1 
ATOM   6869 C CB  . THR B 1 550 ? 126.379 133.581 139.475 1.00 250.34 ?  550  THR B CB  1 
ATOM   6870 O OG1 . THR B 1 550 ? 125.416 132.956 138.616 1.00 250.34 ?  550  THR B OG1 1 
ATOM   6871 C CG2 . THR B 1 550 ? 126.636 134.994 138.974 1.00 250.34 ?  550  THR B CG2 1 
ATOM   6872 N N   . GLY B 1 551 ? 126.184 131.087 140.423 1.00 251.09 ?  551  GLY B N   1 
ATOM   6873 C CA  . GLY B 1 551 ? 125.757 129.729 140.715 1.00 251.09 ?  551  GLY B CA  1 
ATOM   6874 C C   . GLY B 1 551 ? 124.850 129.303 139.583 1.00 251.09 ?  551  GLY B C   1 
ATOM   6875 O O   . GLY B 1 551 ? 124.671 130.054 138.627 1.00 251.09 ?  551  GLY B O   1 
ATOM   6876 N N   . GLN B 1 552 ? 124.252 128.122 139.672 1.00 247.59 ?  552  GLN B N   1 
ATOM   6877 C CA  . GLN B 1 552 ? 123.453 127.637 138.549 1.00 247.59 ?  552  GLN B CA  1 
ATOM   6878 C C   . GLN B 1 552 ? 122.001 127.341 138.865 1.00 247.59 ?  552  GLN B C   1 
ATOM   6879 O O   . GLN B 1 552 ? 121.121 128.111 138.489 1.00 247.59 ?  552  GLN B O   1 
ATOM   6880 C CB  . GLN B 1 552 ? 124.096 126.385 137.950 1.00 247.59 ?  552  GLN B CB  1 
ATOM   6881 C CG  . GLN B 1 552 ? 124.871 126.633 136.671 1.00 247.59 ?  552  GLN B CG  1 
ATOM   6882 C CD  . GLN B 1 552 ? 124.433 125.723 135.545 1.00 247.59 ?  552  GLN B CD  1 
ATOM   6883 O OE1 . GLN B 1 552 ? 124.550 126.067 134.369 1.00 247.59 ?  552  GLN B OE1 1 
ATOM   6884 N NE2 . GLN B 1 552 ? 123.922 124.551 135.899 1.00 247.59 ?  552  GLN B NE2 1 
ATOM   6885 N N   . ILE B 1 553 ? 121.741 126.231 139.547 1.00 216.24 ?  553  ILE B N   1 
ATOM   6886 C CA  . ILE B 1 553 ? 120.362 125.810 139.811 1.00 216.24 ?  553  ILE B CA  1 
ATOM   6887 C C   . ILE B 1 553 ? 119.456 126.822 140.491 1.00 216.24 ?  553  ILE B C   1 
ATOM   6888 O O   . ILE B 1 553 ? 119.947 127.768 141.112 1.00 216.24 ?  553  ILE B O   1 
ATOM   6889 C CB  . ILE B 1 553 ? 120.325 124.488 140.602 1.00 216.24 ?  553  ILE B CB  1 
ATOM   6890 C CG1 . ILE B 1 553 ? 121.716 124.150 141.140 1.00 216.24 ?  553  ILE B CG1 1 
ATOM   6891 C CG2 . ILE B 1 553 ? 119.818 123.360 139.718 1.00 216.24 ?  553  ILE B CG2 1 
ATOM   6892 C CD1 . ILE B 1 553 ? 122.290 122.868 140.577 1.00 216.24 ?  553  ILE B CD1 1 
ATOM   6893 N N   . ALA B 1 554 ? 118.141 126.626 140.371 1.00 188.20 ?  554  ALA B N   1 
ATOM   6894 C CA  . ALA B 1 554 ? 117.149 127.542 140.960 1.00 188.20 ?  554  ALA B CA  1 
ATOM   6895 C C   . ALA B 1 554 ? 117.145 128.918 140.321 1.00 188.20 ?  554  ALA B C   1 
ATOM   6896 O O   . ALA B 1 554 ? 116.427 129.807 140.773 1.00 188.20 ?  554  ALA B O   1 
ATOM   6897 C CB  . ALA B 1 554 ? 117.280 127.634 142.477 1.00 188.20 ?  554  ALA B CB  1 
ATOM   6898 N N   . HIS B 1 555 ? 117.932 129.097 139.268 1.00 232.88 ?  555  HIS B N   1 
ATOM   6899 C CA  . HIS B 1 555 ? 117.952 130.365 138.557 1.00 232.88 ?  555  HIS B CA  1 
ATOM   6900 C C   . HIS B 1 555 ? 118.104 130.074 137.086 1.00 232.88 ?  555  HIS B C   1 
ATOM   6901 O O   . HIS B 1 555 ? 118.263 130.984 136.287 1.00 232.88 ?  555  HIS B O   1 
ATOM   6902 C CB  . HIS B 1 555 ? 119.081 131.265 139.045 1.00 232.88 ?  555  HIS B CB  1 
ATOM   6903 C CG  . HIS B 1 555 ? 118.607 132.430 139.853 1.00 232.88 ?  555  HIS B CG  1 
ATOM   6904 N ND1 . HIS B 1 555 ? 117.290 132.584 140.230 1.00 232.88 ?  555  HIS B ND1 1 
ATOM   6905 C CD2 . HIS B 1 555 ? 119.270 133.497 140.356 1.00 232.88 ?  555  HIS B CD2 1 
ATOM   6906 C CE1 . HIS B 1 555 ? 117.163 133.694 140.932 1.00 232.88 ?  555  HIS B CE1 1 
ATOM   6907 N NE2 . HIS B 1 555 ? 118.349 134.267 141.024 1.00 232.88 ?  555  HIS B NE2 1 
ATOM   6908 N N   . ILE B 1 556 ? 118.053 128.798 136.726 1.00 212.91 ?  556  ILE B N   1 
ATOM   6909 C CA  . ILE B 1 556 ? 118.140 128.427 135.326 1.00 212.91 ?  556  ILE B CA  1 
ATOM   6910 C C   . ILE B 1 556 ? 116.867 128.843 134.625 1.00 212.91 ?  556  ILE B C   1 
ATOM   6911 O O   . ILE B 1 556 ? 116.905 129.645 133.701 1.00 212.91 ?  556  ILE B O   1 
ATOM   6912 C CB  . ILE B 1 556 ? 118.349 126.917 135.149 1.00 212.91 ?  556  ILE B CB  1 
ATOM   6913 C CG1 . ILE B 1 556 ? 119.514 126.438 136.009 1.00 212.91 ?  556  ILE B CG1 1 
ATOM   6914 C CG2 . ILE B 1 556 ? 118.609 126.580 133.690 1.00 212.91 ?  556  ILE B CG2 1 
ATOM   6915 C CD1 . ILE B 1 556 ? 120.770 126.166 135.216 1.00 212.91 ?  556  ILE B CD1 1 
ATOM   6916 N N   . LEU B 1 557 ? 115.736 128.307 135.066 1.00 222.33 ?  557  LEU B N   1 
ATOM   6917 C CA  . LEU B 1 557 ? 114.454 128.680 134.477 1.00 222.33 ?  557  LEU B CA  1 
ATOM   6918 C C   . LEU B 1 557 ? 114.172 130.182 134.566 1.00 222.33 ?  557  LEU B C   1 
ATOM   6919 O O   . LEU B 1 557 ? 113.832 130.789 133.558 1.00 222.33 ?  557  LEU B O   1 
ATOM   6920 C CB  . LEU B 1 557 ? 113.303 127.848 135.060 1.00 222.33 ?  557  LEU B CB  1 
ATOM   6921 C CG  . LEU B 1 557 ? 112.255 127.328 134.079 1.00 222.33 ?  557  LEU B CG  1 
ATOM   6922 C CD1 . LEU B 1 557 ? 110.960 128.112 134.218 1.00 222.33 ?  557  LEU B CD1 1 
ATOM   6923 C CD2 . LEU B 1 557 ? 112.774 127.381 132.650 1.00 222.33 ?  557  LEU B CD2 1 
ATOM   6924 N N   . PRO B 1 558 ? 114.312 130.795 135.759 1.00 213.78 ?  558  PRO B N   1 
ATOM   6925 C CA  . PRO B 1 558 ? 114.122 132.248 135.777 1.00 213.78 ?  558  PRO B CA  1 
ATOM   6926 C C   . PRO B 1 558 ? 114.940 132.963 134.709 1.00 213.78 ?  558  PRO B C   1 
ATOM   6927 O O   . PRO B 1 558 ? 114.382 133.760 133.959 1.00 213.78 ?  558  PRO B O   1 
ATOM   6928 C CB  . PRO B 1 558 ? 114.638 132.641 137.150 1.00 213.78 ?  558  PRO B CB  1 
ATOM   6929 C CG  . PRO B 1 558 ? 114.378 131.465 138.004 1.00 213.78 ?  558  PRO B CG  1 
ATOM   6930 C CD  . PRO B 1 558 ? 114.458 130.253 137.125 1.00 213.78 ?  558  PRO B CD  1 
ATOM   6931 N N   . MET B 1 559 ? 116.238 132.684 134.635 1.00 225.71 ?  559  MET B N   1 
ATOM   6932 C CA  . MET B 1 559 ? 117.095 133.356 133.667 1.00 225.71 ?  559  MET B CA  1 
ATOM   6933 C C   . MET B 1 559 ? 116.702 133.043 132.241 1.00 225.71 ?  559  MET B C   1 
ATOM   6934 O O   . MET B 1 559 ? 116.590 133.942 131.426 1.00 225.71 ?  559  MET B O   1 
ATOM   6935 C CB  . MET B 1 559 ? 118.565 133.013 133.881 1.00 225.71 ?  559  MET B CB  1 
ATOM   6936 C CG  . MET B 1 559 ? 119.504 134.169 133.586 1.00 225.71 ?  559  MET B CG  1 
ATOM   6937 S SD  . MET B 1 559 ? 121.130 133.978 134.333 1.00 225.71 ?  559  MET B SD  1 
ATOM   6938 C CE  . MET B 1 559 ? 120.701 133.756 136.056 1.00 225.71 ?  559  MET B CE  1 
ATOM   6939 N N   . MET B 1 560 ? 116.487 131.773 131.935 1.00 228.96 ?  560  MET B N   1 
ATOM   6940 C CA  . MET B 1 560 ? 116.081 131.389 130.595 1.00 228.96 ?  560  MET B CA  1 
ATOM   6941 C C   . MET B 1 560 ? 114.871 132.185 130.160 1.00 228.96 ?  560  MET B C   1 
ATOM   6942 O O   . MET B 1 560 ? 114.893 132.814 129.112 1.00 228.96 ?  560  MET B O   1 
ATOM   6943 C CB  . MET B 1 560 ? 115.766 129.901 130.538 1.00 228.96 ?  560  MET B CB  1 
ATOM   6944 C CG  . MET B 1 560 ? 116.530 129.148 129.465 1.00 228.96 ?  560  MET B CG  1 
ATOM   6945 S SD  . MET B 1 560 ? 117.699 127.971 130.165 1.00 228.96 ?  560  MET B SD  1 
ATOM   6946 C CE  . MET B 1 560 ? 119.252 128.731 129.699 1.00 228.96 ?  560  MET B CE  1 
ATOM   6947 N N   . VAL B 1 561 ? 113.819 132.172 130.969 1.00 228.93 ?  561  VAL B N   1 
ATOM   6948 C CA  . VAL B 1 561 ? 112.609 132.910 130.636 1.00 228.93 ?  561  VAL B CA  1 
ATOM   6949 C C   . VAL B 1 561 ? 112.943 134.364 130.375 1.00 228.93 ?  561  VAL B C   1 
ATOM   6950 O O   . VAL B 1 561 ? 112.618 134.894 129.319 1.00 228.93 ?  561  VAL B O   1 
ATOM   6951 C CB  . VAL B 1 561 ? 111.548 132.798 131.748 1.00 228.93 ?  561  VAL B CB  1 
ATOM   6952 C CG1 . VAL B 1 561 ? 110.396 133.758 131.498 1.00 228.93 ?  561  VAL B CG1 1 
ATOM   6953 C CG2 . VAL B 1 561 ? 111.031 131.373 131.838 1.00 228.93 ?  561  VAL B CG2 1 
ATOM   6954 N N   . ALA B 1 562 ? 113.621 135.005 131.318 1.00 228.46 ?  562  ALA B N   1 
ATOM   6955 C CA  . ALA B 1 562 ? 113.975 136.408 131.162 1.00 228.46 ?  562  ALA B CA  1 
ATOM   6956 C C   . ALA B 1 562 ? 114.758 136.695 129.887 1.00 228.46 ?  562  ALA B C   1 
ATOM   6957 O O   . ALA B 1 562 ? 114.369 137.555 129.111 1.00 228.46 ?  562  ALA B O   1 
ATOM   6958 C CB  . ALA B 1 562 ? 114.748 136.886 132.368 1.00 228.46 ?  562  ALA B CB  1 
ATOM   6959 N N   . VAL B 1 563 ? 115.857 135.985 129.666 1.00 239.08 ?  563  VAL B N   1 
ATOM   6960 C CA  . VAL B 1 563 ? 116.688 136.236 128.493 1.00 239.08 ?  563  VAL B CA  1 
ATOM   6961 C C   . VAL B 1 563 ? 115.937 135.977 127.191 1.00 239.08 ?  563  VAL B C   1 
ATOM   6962 O O   . VAL B 1 563 ? 116.062 136.745 126.245 1.00 239.08 ?  563  VAL B O   1 
ATOM   6963 C CB  . VAL B 1 563 ? 118.006 135.436 128.536 1.00 239.08 ?  563  VAL B CB  1 
ATOM   6964 C CG1 . VAL B 1 563 ? 118.913 135.838 127.387 1.00 239.08 ?  563  VAL B CG1 1 
ATOM   6965 C CG2 . VAL B 1 563 ? 118.727 135.685 129.849 1.00 239.08 ?  563  VAL B CG2 1 
ATOM   6966 N N   . ILE B 1 564 ? 115.141 134.916 127.140 1.00 243.29 ?  564  ILE B N   1 
ATOM   6967 C CA  . ILE B 1 564 ? 114.351 134.632 125.946 1.00 243.29 ?  564  ILE B CA  1 
ATOM   6968 C C   . ILE B 1 564 ? 113.356 135.754 125.689 1.00 243.29 ?  564  ILE B C   1 
ATOM   6969 O O   . ILE B 1 564 ? 113.255 136.251 124.573 1.00 243.29 ?  564  ILE B O   1 
ATOM   6970 C CB  . ILE B 1 564 ? 113.630 133.274 126.051 1.00 243.29 ?  564  ILE B CB  1 
ATOM   6971 C CG1 . ILE B 1 564 ? 114.622 132.134 125.829 1.00 243.29 ?  564  ILE B CG1 1 
ATOM   6972 C CG2 . ILE B 1 564 ? 112.494 133.169 125.046 1.00 243.29 ?  564  ILE B CG2 1 
ATOM   6973 C CD1 . ILE B 1 564 ? 114.110 130.787 126.284 1.00 243.29 ?  564  ILE B CD1 1 
ATOM   6974 N N   . LEU B 1 565 ? 112.646 136.183 126.726 1.00 267.30 ?  565  LEU B N   1 
ATOM   6975 C CA  . LEU B 1 565 ? 111.690 137.273 126.578 1.00 267.30 ?  565  LEU B CA  1 
ATOM   6976 C C   . LEU B 1 565 ? 112.388 138.554 126.165 1.00 267.30 ?  565  LEU B C   1 
ATOM   6977 O O   . LEU B 1 565 ? 111.878 139.294 125.334 1.00 267.30 ?  565  LEU B O   1 
ATOM   6978 C CB  . LEU B 1 565 ? 110.913 137.484 127.874 1.00 267.30 ?  565  LEU B CB  1 
ATOM   6979 C CG  . LEU B 1 565 ? 109.865 136.420 128.189 1.00 267.30 ?  565  LEU B CG  1 
ATOM   6980 C CD1 . LEU B 1 565 ? 108.951 136.883 129.307 1.00 267.30 ?  565  LEU B CD1 1 
ATOM   6981 C CD2 . LEU B 1 565 ? 109.061 136.066 126.950 1.00 267.30 ?  565  LEU B CD2 1 
ATOM   6982 N N   . ALA B 1 566 ? 113.557 138.817 126.733 1.00 262.27 ?  566  ALA B N   1 
ATOM   6983 C CA  . ALA B 1 566 ? 114.319 140.000 126.366 1.00 262.27 ?  566  ALA B CA  1 
ATOM   6984 C C   . ALA B 1 566 ? 114.683 139.944 124.904 1.00 262.27 ?  566  ALA B C   1 
ATOM   6985 O O   . ALA B 1 566 ? 114.443 140.893 124.169 1.00 262.27 ?  566  ALA B O   1 
ATOM   6986 C CB  . ALA B 1 566 ? 115.570 140.097 127.208 1.00 262.27 ?  566  ALA B CB  1 
ATOM   6987 N N   . ASN B 1 567 ? 115.259 138.830 124.475 1.00 256.31 ?  567  ASN B N   1 
ATOM   6988 C CA  . ASN B 1 567 ? 115.632 138.670 123.081 1.00 256.31 ?  567  ASN B CA  1 
ATOM   6989 C C   . ASN B 1 567 ? 114.435 138.932 122.199 1.00 256.31 ?  567  ASN B C   1 
ATOM   6990 O O   . ASN B 1 567 ? 114.524 139.703 121.260 1.00 256.31 ?  567  ASN B O   1 
ATOM   6991 C CB  . ASN B 1 567 ? 116.148 137.259 122.827 1.00 256.31 ?  567  ASN B CB  1 
ATOM   6992 C CG  . ASN B 1 567 ? 117.640 137.143 123.008 1.00 256.31 ?  567  ASN B CG  1 
ATOM   6993 O OD1 . ASN B 1 567 ? 118.360 136.814 122.072 1.00 256.31 ?  567  ASN B OD1 1 
ATOM   6994 N ND2 . ASN B 1 567 ? 118.111 137.400 124.219 1.00 256.31 ?  567  ASN B ND2 1 
ATOM   6995 N N   . MET B 1 568 ? 113.310 138.299 122.503 1.00 259.23 ?  568  MET B N   1 
ATOM   6996 C CA  . MET B 1 568 ? 112.106 138.469 121.702 1.00 259.23 ?  568  MET B CA  1 
ATOM   6997 C C   . MET B 1 568 ? 111.702 139.926 121.554 1.00 259.23 ?  568  MET B C   1 
ATOM   6998 O O   . MET B 1 568 ? 111.565 140.424 120.440 1.00 259.23 ?  568  MET B O   1 
ATOM   6999 C CB  . MET B 1 568 ? 110.955 137.673 122.308 1.00 259.23 ?  568  MET B CB  1 
ATOM   7000 C CG  . MET B 1 568 ? 111.015 136.184 122.021 1.00 259.23 ?  568  MET B CG  1 
ATOM   7001 S SD  . MET B 1 568 ? 109.728 135.290 122.907 1.00 259.23 ?  568  MET B SD  1 
ATOM   7002 C CE  . MET B 1 568 ? 108.513 136.589 123.116 1.00 259.23 ?  568  MET B CE  1 
ATOM   7003 N N   . VAL B 1 569 ? 111.508 140.613 122.672 1.00 227.12 ?  569  VAL B N   1 
ATOM   7004 C CA  . VAL B 1 569 ? 111.107 142.012 122.626 1.00 227.12 ?  569  VAL B CA  1 
ATOM   7005 C C   . VAL B 1 569 ? 112.121 142.842 121.851 1.00 227.12 ?  569  VAL B C   1 
ATOM   7006 O O   . VAL B 1 569 ? 111.752 143.607 120.962 1.00 227.12 ?  569  VAL B O   1 
ATOM   7007 C CB  . VAL B 1 569 ? 110.908 142.591 124.040 1.00 227.12 ?  569  VAL B CB  1 
ATOM   7008 C CG1 . VAL B 1 569 ? 110.499 144.051 123.967 1.00 227.12 ?  569  VAL B CG1 1 
ATOM   7009 C CG2 . VAL B 1 569 ? 109.854 141.795 124.790 1.00 227.12 ?  569  VAL B CG2 1 
ATOM   7010 N N   . ALA B 1 570 ? 113.400 142.678 122.160 1.00 244.26 ?  570  ALA B N   1 
ATOM   7011 C CA  . ALA B 1 570 ? 114.435 143.461 121.495 1.00 244.26 ?  570  ALA B CA  1 
ATOM   7012 C C   . ALA B 1 570 ? 114.532 143.168 120.009 1.00 244.26 ?  570  ALA B C   1 
ATOM   7013 O O   . ALA B 1 570 ? 114.690 144.083 119.212 1.00 244.26 ?  570  ALA B O   1 
ATOM   7014 C CB  . ALA B 1 570 ? 115.773 143.235 122.158 1.00 244.26 ?  570  ALA B CB  1 
ATOM   7015 N N   . GLN B 1 571 ? 114.439 141.900 119.631 1.00 249.88 ?  571  GLN B N   1 
ATOM   7016 C CA  . GLN B 1 571 ? 114.527 141.527 118.227 1.00 249.88 ?  571  GLN B CA  1 
ATOM   7017 C C   . GLN B 1 571 ? 113.384 142.137 117.449 1.00 249.88 ?  571  GLN B C   1 
ATOM   7018 O O   . GLN B 1 571 ? 113.551 142.526 116.296 1.00 249.88 ?  571  GLN B O   1 
ATOM   7019 C CB  . GLN B 1 571 ? 114.503 140.010 118.070 1.00 249.88 ?  571  GLN B CB  1 
ATOM   7020 C CG  . GLN B 1 571 ? 115.864 139.381 117.837 1.00 249.88 ?  571  GLN B CG  1 
ATOM   7021 C CD  . GLN B 1 571 ? 116.084 138.147 118.685 1.00 249.88 ?  571  GLN B CD  1 
ATOM   7022 O OE1 . GLN B 1 571 ? 117.181 137.915 119.190 1.00 249.88 ?  571  GLN B OE1 1 
ATOM   7023 N NE2 . GLN B 1 571 ? 115.038 137.348 118.848 1.00 249.88 ?  571  GLN B NE2 1 
ATOM   7024 N N   . SER B 1 572 ? 112.219 142.227 118.077 1.00 280.35 ?  572  SER B N   1 
ATOM   7025 C CA  . SER B 1 572 ? 111.059 142.800 117.418 1.00 280.35 ?  572  SER B CA  1 
ATOM   7026 C C   . SER B 1 572 ? 111.185 144.302 117.251 1.00 280.35 ?  572  SER B C   1 
ATOM   7027 O O   . SER B 1 572 ? 110.559 144.881 116.367 1.00 280.35 ?  572  SER B O   1 
ATOM   7028 C CB  . SER B 1 572 ? 109.800 142.476 118.214 1.00 280.35 ?  572  SER B CB  1 
ATOM   7029 O OG  . SER B 1 572 ? 109.506 143.501 119.143 1.00 280.35 ?  572  SER B OG  1 
ATOM   7030 N N   . LEU B 1 573 ? 111.991 144.942 118.088 1.00 229.04 ?  573  LEU B N   1 
ATOM   7031 C CA  . LEU B 1 573 ? 112.098 146.394 118.037 1.00 229.04 ?  573  LEU B CA  1 
ATOM   7032 C C   . LEU B 1 573 ? 113.303 146.909 117.261 1.00 229.04 ?  573  LEU B C   1 
ATOM   7033 O O   . LEU B 1 573 ? 113.138 147.555 116.230 1.00 229.04 ?  573  LEU B O   1 
ATOM   7034 C CB  . LEU B 1 573 ? 112.090 146.970 119.449 1.00 229.04 ?  573  LEU B CB  1 
ATOM   7035 C CG  . LEU B 1 573 ? 110.816 146.757 120.263 1.00 229.04 ?  573  LEU B CG  1 
ATOM   7036 C CD1 . LEU B 1 573 ? 111.023 147.210 121.698 1.00 229.04 ?  573  LEU B CD1 1 
ATOM   7037 C CD2 . LEU B 1 573 ? 109.644 147.486 119.628 1.00 229.04 ?  573  LEU B CD2 1 
ATOM   7038 N N   . GLN B 1 574 ? 114.511 146.643 117.746 1.00 226.72 ?  574  GLN B N   1 
ATOM   7039 C CA  . GLN B 1 574 ? 115.708 147.170 117.093 1.00 226.72 ?  574  GLN B CA  1 
ATOM   7040 C C   . GLN B 1 574 ? 116.690 146.072 116.724 1.00 226.72 ?  574  GLN B C   1 
ATOM   7041 O O   . GLN B 1 574 ? 116.551 144.946 117.183 1.00 226.72 ?  574  GLN B O   1 
ATOM   7042 C CB  . GLN B 1 574 ? 116.400 148.197 118.002 1.00 226.72 ?  574  GLN B CB  1 
ATOM   7043 C CG  . GLN B 1 574 ? 115.596 149.454 118.291 1.00 226.72 ?  574  GLN B CG  1 
ATOM   7044 C CD  . GLN B 1 574 ? 115.203 150.214 117.041 1.00 226.72 ?  574  GLN B CD  1 
ATOM   7045 O OE1 . GLN B 1 574 ? 116.024 150.451 116.159 1.00 226.72 ?  574  GLN B OE1 1 
ATOM   7046 N NE2 . GLN B 1 574 ? 113.938 150.608 116.964 1.00 226.72 ?  574  GLN B NE2 1 
ATOM   7047 N N   . PRO B 1 575 ? 117.685 146.384 115.875 1.00 270.67 ?  575  PRO B N   1 
ATOM   7048 C CA  . PRO B 1 575 ? 118.721 145.387 115.579 1.00 270.67 ?  575  PRO B CA  1 
ATOM   7049 C C   . PRO B 1 575 ? 119.655 145.166 116.764 1.00 270.67 ?  575  PRO B C   1 
ATOM   7050 O O   . PRO B 1 575 ? 119.514 145.830 117.785 1.00 270.67 ?  575  PRO B O   1 
ATOM   7051 C CB  . PRO B 1 575 ? 119.503 146.031 114.436 1.00 270.67 ?  575  PRO B CB  1 
ATOM   7052 C CG  . PRO B 1 575 ? 118.552 146.979 113.801 1.00 270.67 ?  575  PRO B CG  1 
ATOM   7053 C CD  . PRO B 1 575 ? 117.722 147.511 114.927 1.00 270.67 ?  575  PRO B CD  1 
ATOM   7054 N N   . SER B 1 576 ? 120.602 144.245 116.641 1.00 286.08 ?  576  SER B N   1 
ATOM   7055 C CA  . SER B 1 576 ? 121.564 144.024 117.712 1.00 286.08 ?  576  SER B CA  1 
ATOM   7056 C C   . SER B 1 576 ? 122.569 145.153 117.690 1.00 286.08 ?  576  SER B C   1 
ATOM   7057 O O   . SER B 1 576 ? 122.682 145.856 116.697 1.00 286.08 ?  576  SER B O   1 
ATOM   7058 C CB  . SER B 1 576 ? 122.275 142.688 117.530 1.00 286.08 ?  576  SER B CB  1 
ATOM   7059 O OG  . SER B 1 576 ? 123.621 142.870 117.136 1.00 286.08 ?  576  SER B OG  1 
ATOM   7060 N N   . LEU B 1 577 ? 123.302 145.336 118.778 1.00 272.66 ?  577  LEU B N   1 
ATOM   7061 C CA  . LEU B 1 577 ? 124.305 146.384 118.826 1.00 272.66 ?  577  LEU B CA  1 
ATOM   7062 C C   . LEU B 1 577 ? 125.245 146.217 117.665 1.00 272.66 ?  577  LEU B C   1 
ATOM   7063 O O   . LEU B 1 577 ? 125.476 147.153 116.915 1.00 272.66 ?  577  LEU B O   1 
ATOM   7064 C CB  . LEU B 1 577 ? 125.096 146.321 120.130 1.00 272.66 ?  577  LEU B CB  1 
ATOM   7065 C CG  . LEU B 1 577 ? 125.307 147.628 120.893 1.00 272.66 ?  577  LEU B CG  1 
ATOM   7066 C CD1 . LEU B 1 577 ? 126.789 147.906 121.080 1.00 272.66 ?  577  LEU B CD1 1 
ATOM   7067 C CD2 . LEU B 1 577 ? 124.617 148.790 120.199 1.00 272.66 ?  577  LEU B CD2 1 
ATOM   7068 N N   . TYR B 1 578 ? 125.777 145.018 117.496 1.00 288.67 ?  578  TYR B N   1 
ATOM   7069 C CA  . TYR B 1 578 ? 126.749 144.774 116.443 1.00 288.67 ?  578  TYR B CA  1 
ATOM   7070 C C   . TYR B 1 578 ? 126.162 144.911 115.053 1.00 288.67 ?  578  TYR B C   1 
ATOM   7071 O O   . TYR B 1 578 ? 126.824 145.407 114.153 1.00 288.67 ?  578  TYR B O   1 
ATOM   7072 C CB  . TYR B 1 578 ? 127.377 143.403 116.651 1.00 288.67 ?  578  TYR B CB  1 
ATOM   7073 C CG  . TYR B 1 578 ? 127.634 143.125 118.109 1.00 288.67 ?  578  TYR B CG  1 
ATOM   7074 C CD1 . TYR B 1 578 ? 128.530 143.900 118.835 1.00 288.67 ?  578  TYR B CD1 1 
ATOM   7075 C CD2 . TYR B 1 578 ? 126.961 142.111 118.769 1.00 288.67 ?  578  TYR B CD2 1 
ATOM   7076 C CE1 . TYR B 1 578 ? 128.758 143.660 120.174 1.00 288.67 ?  578  TYR B CE1 1 
ATOM   7077 C CE2 . TYR B 1 578 ? 127.184 141.865 120.106 1.00 288.67 ?  578  TYR B CE2 1 
ATOM   7078 C CZ  . TYR B 1 578 ? 128.081 142.640 120.802 1.00 288.67 ?  578  TYR B CZ  1 
ATOM   7079 O OH  . TYR B 1 578 ? 128.294 142.390 122.133 1.00 288.67 ?  578  TYR B OH  1 
ATOM   7080 N N   . ASP B 1 579 ? 124.916 144.494 114.876 1.00 309.79 ?  579  ASP B N   1 
ATOM   7081 C CA  . ASP B 1 579 ? 124.262 144.642 113.585 1.00 309.79 ?  579  ASP B CA  1 
ATOM   7082 C C   . ASP B 1 579 ? 123.984 146.101 113.294 1.00 309.79 ?  579  ASP B C   1 
ATOM   7083 O O   . ASP B 1 579 ? 124.094 146.539 112.155 1.00 309.79 ?  579  ASP B O   1 
ATOM   7084 C CB  . ASP B 1 579 ? 122.970 143.837 113.542 1.00 309.79 ?  579  ASP B CB  1 
ATOM   7085 C CG  . ASP B 1 579 ? 123.218 142.354 113.388 1.00 309.79 ?  579  ASP B CG  1 
ATOM   7086 O OD1 . ASP B 1 579 ? 124.069 141.979 112.555 1.00 309.79 ?  579  ASP B OD1 1 
ATOM   7087 O OD2 . ASP B 1 579 ? 122.566 141.564 114.099 1.00 309.79 -1 579  ASP B OD2 1 
ATOM   7088 N N   . SER B 1 580 ? 123.636 146.864 114.319 1.00 294.72 ?  580  SER B N   1 
ATOM   7089 C CA  . SER B 1 580 ? 123.399 148.286 114.135 1.00 294.72 ?  580  SER B CA  1 
ATOM   7090 C C   . SER B 1 580 ? 124.696 149.008 113.816 1.00 294.72 ?  580  SER B C   1 
ATOM   7091 O O   . SER B 1 580 ? 124.699 149.953 113.039 1.00 294.72 ?  580  SER B O   1 
ATOM   7092 C CB  . SER B 1 580 ? 122.744 148.891 115.373 1.00 294.72 ?  580  SER B CB  1 
ATOM   7093 O OG  . SER B 1 580 ? 123.672 149.646 116.131 1.00 294.72 ?  580  SER B OG  1 
ATOM   7094 N N   . ILE B 1 581 ? 125.801 148.564 114.406 1.00 282.70 ?  581  ILE B N   1 
ATOM   7095 C CA  . ILE B 1 581 ? 127.092 149.174 114.122 1.00 282.70 ?  581  ILE B CA  1 
ATOM   7096 C C   . ILE B 1 581 ? 127.488 148.827 112.700 1.00 282.70 ?  581  ILE B C   1 
ATOM   7097 O O   . ILE B 1 581 ? 128.032 149.663 111.986 1.00 282.70 ?  581  ILE B O   1 
ATOM   7098 C CB  . ILE B 1 581 ? 128.165 148.736 115.134 1.00 282.70 ?  581  ILE B CB  1 
ATOM   7099 C CG1 . ILE B 1 581 ? 127.833 149.273 116.525 1.00 282.70 ?  581  ILE B CG1 1 
ATOM   7100 C CG2 . ILE B 1 581 ? 129.538 149.245 114.733 1.00 282.70 ?  581  ILE B CG2 1 
ATOM   7101 C CD1 . ILE B 1 581 ? 128.692 148.689 117.624 1.00 282.70 ?  581  ILE B CD1 1 
ATOM   7102 N N   . ILE B 1 582 ? 127.192 147.608 112.265 1.00 277.28 ?  582  ILE B N   1 
ATOM   7103 C CA  . ILE B 1 582 ? 127.464 147.235 110.884 1.00 277.28 ?  582  ILE B CA  1 
ATOM   7104 C C   . ILE B 1 582 ? 126.757 148.228 109.976 1.00 277.28 ?  582  ILE B C   1 
ATOM   7105 O O   . ILE B 1 582 ? 127.365 148.774 109.060 1.00 277.28 ?  582  ILE B O   1 
ATOM   7106 C CB  . ILE B 1 582 ? 126.993 145.797 110.583 1.00 277.28 ?  582  ILE B CB  1 
ATOM   7107 C CG1 . ILE B 1 582 ? 128.034 144.783 111.051 1.00 277.28 ?  582  ILE B CG1 1 
ATOM   7108 C CG2 . ILE B 1 582 ? 126.715 145.598 109.101 1.00 277.28 ?  582  ILE B CG2 1 
ATOM   7109 C CD1 . ILE B 1 582 ? 127.502 143.371 111.141 1.00 277.28 ?  582  ILE B CD1 1 
ATOM   7110 N N   . GLN B 1 583 ? 125.483 148.496 110.246 1.00 314.83 ?  583  GLN B N   1 
ATOM   7111 C CA  . GLN B 1 583 ? 124.723 149.443 109.436 1.00 314.83 ?  583  GLN B CA  1 
ATOM   7112 C C   . GLN B 1 583 ? 125.304 150.851 109.461 1.00 314.83 ?  583  GLN B C   1 
ATOM   7113 O O   . GLN B 1 583 ? 125.385 151.502 108.424 1.00 314.83 ?  583  GLN B O   1 
ATOM   7114 C CB  . GLN B 1 583 ? 123.269 149.482 109.894 1.00 314.83 ?  583  GLN B CB  1 
ATOM   7115 C CG  . GLN B 1 583 ? 122.494 148.208 109.616 1.00 314.83 ?  583  GLN B CG  1 
ATOM   7116 C CD  . GLN B 1 583 ? 121.476 147.904 110.696 1.00 314.83 ?  583  GLN B CD  1 
ATOM   7117 O OE1 . GLN B 1 583 ? 120.990 148.806 111.378 1.00 314.83 ?  583  GLN B OE1 1 
ATOM   7118 N NE2 . GLN B 1 583 ? 121.151 146.627 110.860 1.00 314.83 ?  583  GLN B NE2 1 
ATOM   7119 N N   . VAL B 1 584 ? 125.697 151.329 110.636 1.00 286.70 ?  584  VAL B N   1 
ATOM   7120 C CA  . VAL B 1 584 ? 126.298 152.657 110.747 1.00 286.70 ?  584  VAL B CA  1 
ATOM   7121 C C   . VAL B 1 584 ? 127.552 152.740 109.890 1.00 286.70 ?  584  VAL B C   1 
ATOM   7122 O O   . VAL B 1 584 ? 127.727 153.690 109.127 1.00 286.70 ?  584  VAL B O   1 
ATOM   7123 C CB  . VAL B 1 584 ? 126.647 153.007 112.210 1.00 286.70 ?  584  VAL B CB  1 
ATOM   7124 C CG1 . VAL B 1 584 ? 127.491 154.270 112.286 1.00 286.70 ?  584  VAL B CG1 1 
ATOM   7125 C CG2 . VAL B 1 584 ? 125.382 153.175 113.032 1.00 286.70 ?  584  VAL B CG2 1 
ATOM   7126 N N   . LYS B 1 585 ? 128.414 151.735 109.987 1.00 267.69 ?  585  LYS B N   1 
ATOM   7127 C CA  . LYS B 1 585 ? 129.656 151.737 109.225 1.00 267.69 ?  585  LYS B CA  1 
ATOM   7128 C C   . LYS B 1 585 ? 129.455 151.232 107.809 1.00 267.69 ?  585  LYS B C   1 
ATOM   7129 O O   . LYS B 1 585 ? 130.427 151.078 107.072 1.00 267.69 ?  585  LYS B O   1 
ATOM   7130 C CB  . LYS B 1 585 ? 130.706 150.885 109.932 1.00 267.69 ?  585  LYS B CB  1 
ATOM   7131 C CG  . LYS B 1 585 ? 130.935 151.266 111.384 1.00 267.69 ?  585  LYS B CG  1 
ATOM   7132 C CD  . LYS B 1 585 ? 132.417 151.348 111.705 1.00 267.69 ?  585  LYS B CD  1 
ATOM   7133 C CE  . LYS B 1 585 ? 132.791 150.386 112.819 1.00 267.69 ?  585  LYS B CE  1 
ATOM   7134 N NZ  . LYS B 1 585 ? 132.279 149.015 112.551 1.00 267.69 1  585  LYS B NZ  1 
ATOM   7135 N N   . LYS B 1 586 ? 128.208 150.966 107.429 1.00 276.08 ?  586  LYS B N   1 
ATOM   7136 C CA  . LYS B 1 586 ? 127.895 150.470 106.086 1.00 276.08 ?  586  LYS B CA  1 
ATOM   7137 C C   . LYS B 1 586 ? 128.792 149.313 105.695 1.00 276.08 ?  586  LYS B C   1 
ATOM   7138 O O   . LYS B 1 586 ? 129.276 149.252 104.567 1.00 276.08 ?  586  LYS B O   1 
ATOM   7139 C CB  . LYS B 1 586 ? 127.974 151.596 105.053 1.00 276.08 ?  586  LYS B CB  1 
ATOM   7140 C CG  . LYS B 1 586 ? 126.722 152.453 104.976 1.00 276.08 ?  586  LYS B CG  1 
ATOM   7141 C CD  . LYS B 1 586 ? 126.923 153.799 105.653 1.00 276.08 ?  586  LYS B CD  1 
ATOM   7142 C CE  . LYS B 1 586 ? 128.308 154.359 105.376 1.00 276.08 ?  586  LYS B CE  1 
ATOM   7143 N NZ  . LYS B 1 586 ? 129.006 154.765 106.627 1.00 276.08 1  586  LYS B NZ  1 
ATOM   7144 N N   . LEU B 1 587 ? 129.013 148.391 106.624 1.00 300.88 ?  587  LEU B N   1 
ATOM   7145 C CA  . LEU B 1 587 ? 129.871 147.251 106.352 1.00 300.88 ?  587  LEU B CA  1 
ATOM   7146 C C   . LEU B 1 587 ? 129.173 146.321 105.382 1.00 300.88 ?  587  LEU B C   1 
ATOM   7147 O O   . LEU B 1 587 ? 127.989 146.029 105.548 1.00 300.88 ?  587  LEU B O   1 
ATOM   7148 C CB  . LEU B 1 587 ? 130.217 146.520 107.649 1.00 300.88 ?  587  LEU B CB  1 
ATOM   7149 C CG  . LEU B 1 587 ? 131.303 147.170 108.504 1.00 300.88 ?  587  LEU B CG  1 
ATOM   7150 C CD1 . LEU B 1 587 ? 131.216 146.689 109.942 1.00 300.88 ?  587  LEU B CD1 1 
ATOM   7151 C CD2 . LEU B 1 587 ? 132.679 146.885 107.924 1.00 300.88 ?  587  LEU B CD2 1 
ATOM   7152 N N   . PRO B 1 588 ? 129.898 145.854 104.357 1.00 320.95 ?  588  PRO B N   1 
ATOM   7153 C CA  . PRO B 1 588 ? 129.314 144.962 103.351 1.00 320.95 ?  588  PRO B CA  1 
ATOM   7154 C C   . PRO B 1 588 ? 128.574 143.799 103.979 1.00 320.95 ?  588  PRO B C   1 
ATOM   7155 O O   . PRO B 1 588 ? 127.491 143.455 103.504 1.00 320.95 ?  588  PRO B O   1 
ATOM   7156 C CB  . PRO B 1 588 ? 130.539 144.444 102.606 1.00 320.95 ?  588  PRO B CB  1 
ATOM   7157 C CG  . PRO B 1 588 ? 131.536 145.543 102.727 1.00 320.95 ?  588  PRO B CG  1 
ATOM   7158 C CD  . PRO B 1 588 ? 131.316 146.148 104.083 1.00 320.95 ?  588  PRO B CD  1 
ATOM   7159 N N   . TYR B 1 589 ? 129.151 143.199 105.014 1.00 335.86 ?  589  TYR B N   1 
ATOM   7160 C CA  . TYR B 1 589 ? 128.511 142.090 105.705 1.00 335.86 ?  589  TYR B CA  1 
ATOM   7161 C C   . TYR B 1 589 ? 128.067 141.019 104.719 1.00 335.86 ?  589  TYR B C   1 
ATOM   7162 O O   . TYR B 1 589 ? 128.872 140.211 104.259 1.00 335.86 ?  589  TYR B O   1 
ATOM   7163 C CB  . TYR B 1 589 ? 127.333 142.600 106.538 1.00 335.86 ?  589  TYR B CB  1 
ATOM   7164 C CG  . TYR B 1 589 ? 126.755 141.592 107.498 1.00 335.86 ?  589  TYR B CG  1 
ATOM   7165 C CD1 . TYR B 1 589 ? 127.570 140.699 108.176 1.00 335.86 ?  589  TYR B CD1 1 
ATOM   7166 C CD2 . TYR B 1 589 ? 125.391 141.543 107.733 1.00 335.86 ?  589  TYR B CD2 1 
ATOM   7167 C CE1 . TYR B 1 589 ? 127.037 139.781 109.056 1.00 335.86 ?  589  TYR B CE1 1 
ATOM   7168 C CE2 . TYR B 1 589 ? 124.849 140.627 108.609 1.00 335.86 ?  589  TYR B CE2 1 
ATOM   7169 C CZ  . TYR B 1 589 ? 125.676 139.748 109.267 1.00 335.86 ?  589  TYR B CZ  1 
ATOM   7170 O OH  . TYR B 1 589 ? 125.133 138.836 110.140 1.00 335.86 ?  589  TYR B OH  1 
HETATM 7171 S S   . SCN C 2 .   ? 119.300 108.095 128.031 1.00 10.00  ?  1001 SCN A S   1 
HETATM 7172 C C   . SCN C 2 .   ? 119.051 109.497 128.938 1.00 10.00  ?  1001 SCN A C   1 
HETATM 7173 N N   . SCN C 2 .   ? 118.881 110.456 129.558 1.00 10.00  ?  1001 SCN A N   1 
HETATM 7174 S S   . SCN D 2 .   ? 127.351 111.826 117.175 1.00 10.00  ?  1002 SCN A S   1 
HETATM 7175 C C   . SCN D 2 .   ? 128.424 113.127 117.114 1.00 10.00  ?  1002 SCN A C   1 
HETATM 7176 N N   . SCN D 2 .   ? 129.159 114.019 117.072 1.00 10.00  ?  1002 SCN A N   1 
HETATM 7177 S S   . SCN E 2 .   ? 115.132 104.282 134.494 1.00 10.00  ?  1003 SCN A S   1 
HETATM 7178 C C   . SCN E 2 .   ? 115.914 105.670 133.934 1.00 10.00  ?  1003 SCN A C   1 
HETATM 7179 N N   . SCN E 2 .   ? 116.449 106.622 133.551 1.00 10.00  ?  1003 SCN A N   1 
HETATM 7180 S S   . SCN F 2 .   ? 132.700 143.905 128.031 1.00 10.00  ?  1001 SCN B S   1 
HETATM 7181 C C   . SCN F 2 .   ? 132.949 142.503 128.938 1.00 10.00  ?  1001 SCN B C   1 
HETATM 7182 N N   . SCN F 2 .   ? 133.119 141.544 129.558 1.00 10.00  ?  1001 SCN B N   1 
HETATM 7183 S S   . SCN G 2 .   ? 124.649 140.174 117.175 1.00 10.00  ?  1002 SCN B S   1 
HETATM 7184 C C   . SCN G 2 .   ? 123.576 138.873 117.114 1.00 10.00  ?  1002 SCN B C   1 
HETATM 7185 N N   . SCN G 2 .   ? 122.841 137.981 117.072 1.00 10.00  ?  1002 SCN B N   1 
HETATM 7186 S S   . SCN H 2 .   ? 136.868 147.718 134.494 1.00 10.00  ?  1003 SCN B S   1 
HETATM 7187 C C   . SCN H 2 .   ? 136.086 146.330 133.934 1.00 10.00  ?  1003 SCN B C   1 
HETATM 7188 N N   . SCN H 2 .   ? 135.551 145.378 133.551 1.00 10.00  ?  1003 SCN B N   1 
# 
