data_8WXI
# 
_entry.id   8WXI 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8WXI         pdb_00008wxi 10.2210/pdb8wxi/pdb 
WWPDB D_1300042202 ?            ?                   
EMDB  EMD-37908    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-20 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8WXI 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-29 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'human CLC-1 D136G delayed rectification' 
_pdbx_database_related.db_id          EMD-37908 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhangmingfeng@westlake.edu.cn 
_pdbx_contact_author.name_first         Mingfeng 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0138-3934 
# 
_audit_author.name               'Zhang, M.F.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0002-0138-3934 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'CLC-1 in SCN environment' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
_citation_author.citation_id        primary 
_citation_author.name               'Zhang, M.F.' 
_citation_author.ordinal            1 
_citation_author.identifier_ORCID   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Chloride channel protein 1' 108675.133 2 ? D136G ? ? 
2 non-polymer syn 'THIOCYANATE ION'            58.082     8 ? ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQIYGHHKEQFSDREQDIGMPK
KTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIFLVLLGLLMALVSWSMGYVSAKSLQAYKWSYAQMQPSLPLQ
FLVWVTFPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIAS
ICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLA
VWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFV
IASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIP
CGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMM
VAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLV
DSKDSMILLGSVERSELQALLQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLS
GKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRARPTKKKTTQDSTDLVDNMSPE
EIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQL
RPPLASFRNTTSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESP
GLEEELADILQGPSLRSTDEEDEDELIL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQIYGHHKEQFSDREQDIGMPK
KTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIFLVLLGLLMALVSWSMGYVSAKSLQAYKWSYAQMQPSLPLQ
FLVWVTFPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIAS
ICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLA
VWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFV
IASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIP
CGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMM
VAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLV
DSKDSMILLGSVERSELQALLQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLS
GKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRARPTKKKTTQDSTDLVDNMSPE
EIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQL
RPPLASFRNTTSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESP
GLEEELADILQGPSLRSTDEEDEDELIL
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'THIOCYANATE ION' 
_pdbx_entity_nonpoly.comp_id     SCN 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLU n 
1 3   GLN n 
1 4   SER n 
1 5   ARG n 
1 6   SER n 
1 7   GLN n 
1 8   GLN n 
1 9   ARG n 
1 10  GLY n 
1 11  GLY n 
1 12  GLU n 
1 13  GLN n 
1 14  SER n 
1 15  TRP n 
1 16  TRP n 
1 17  GLY n 
1 18  SER n 
1 19  ASP n 
1 20  PRO n 
1 21  GLN n 
1 22  TYR n 
1 23  GLN n 
1 24  TYR n 
1 25  MET n 
1 26  PRO n 
1 27  PHE n 
1 28  GLU n 
1 29  HIS n 
1 30  CYS n 
1 31  THR n 
1 32  SER n 
1 33  TYR n 
1 34  GLY n 
1 35  LEU n 
1 36  PRO n 
1 37  SER n 
1 38  GLU n 
1 39  ASN n 
1 40  GLY n 
1 41  GLY n 
1 42  LEU n 
1 43  GLN n 
1 44  HIS n 
1 45  ARG n 
1 46  LEU n 
1 47  ARG n 
1 48  LYS n 
1 49  ASP n 
1 50  ALA n 
1 51  GLY n 
1 52  PRO n 
1 53  ARG n 
1 54  HIS n 
1 55  ASN n 
1 56  VAL n 
1 57  HIS n 
1 58  PRO n 
1 59  THR n 
1 60  GLN n 
1 61  ILE n 
1 62  TYR n 
1 63  GLY n 
1 64  HIS n 
1 65  HIS n 
1 66  LYS n 
1 67  GLU n 
1 68  GLN n 
1 69  PHE n 
1 70  SER n 
1 71  ASP n 
1 72  ARG n 
1 73  GLU n 
1 74  GLN n 
1 75  ASP n 
1 76  ILE n 
1 77  GLY n 
1 78  MET n 
1 79  PRO n 
1 80  LYS n 
1 81  LYS n 
1 82  THR n 
1 83  GLY n 
1 84  SER n 
1 85  SER n 
1 86  SER n 
1 87  THR n 
1 88  VAL n 
1 89  ASP n 
1 90  SER n 
1 91  LYS n 
1 92  ASP n 
1 93  GLU n 
1 94  ASP n 
1 95  HIS n 
1 96  TYR n 
1 97  SER n 
1 98  LYS n 
1 99  CYS n 
1 100 GLN n 
1 101 ASP n 
1 102 CYS n 
1 103 ILE n 
1 104 HIS n 
1 105 ARG n 
1 106 LEU n 
1 107 GLY n 
1 108 GLN n 
1 109 VAL n 
1 110 VAL n 
1 111 ARG n 
1 112 ARG n 
1 113 LYS n 
1 114 LEU n 
1 115 GLY n 
1 116 GLU n 
1 117 ASP n 
1 118 GLY n 
1 119 ILE n 
1 120 PHE n 
1 121 LEU n 
1 122 VAL n 
1 123 LEU n 
1 124 LEU n 
1 125 GLY n 
1 126 LEU n 
1 127 LEU n 
1 128 MET n 
1 129 ALA n 
1 130 LEU n 
1 131 VAL n 
1 132 SER n 
1 133 TRP n 
1 134 SER n 
1 135 MET n 
1 136 GLY n 
1 137 TYR n 
1 138 VAL n 
1 139 SER n 
1 140 ALA n 
1 141 LYS n 
1 142 SER n 
1 143 LEU n 
1 144 GLN n 
1 145 ALA n 
1 146 TYR n 
1 147 LYS n 
1 148 TRP n 
1 149 SER n 
1 150 TYR n 
1 151 ALA n 
1 152 GLN n 
1 153 MET n 
1 154 GLN n 
1 155 PRO n 
1 156 SER n 
1 157 LEU n 
1 158 PRO n 
1 159 LEU n 
1 160 GLN n 
1 161 PHE n 
1 162 LEU n 
1 163 VAL n 
1 164 TRP n 
1 165 VAL n 
1 166 THR n 
1 167 PHE n 
1 168 PRO n 
1 169 LEU n 
1 170 VAL n 
1 171 LEU n 
1 172 ILE n 
1 173 LEU n 
1 174 PHE n 
1 175 SER n 
1 176 ALA n 
1 177 LEU n 
1 178 PHE n 
1 179 CYS n 
1 180 HIS n 
1 181 LEU n 
1 182 ILE n 
1 183 SER n 
1 184 PRO n 
1 185 GLN n 
1 186 ALA n 
1 187 VAL n 
1 188 GLY n 
1 189 SER n 
1 190 GLY n 
1 191 ILE n 
1 192 PRO n 
1 193 GLU n 
1 194 MET n 
1 195 LYS n 
1 196 THR n 
1 197 ILE n 
1 198 LEU n 
1 199 ARG n 
1 200 GLY n 
1 201 VAL n 
1 202 VAL n 
1 203 LEU n 
1 204 LYS n 
1 205 GLU n 
1 206 TYR n 
1 207 LEU n 
1 208 THR n 
1 209 MET n 
1 210 LYS n 
1 211 ALA n 
1 212 PHE n 
1 213 VAL n 
1 214 ALA n 
1 215 LYS n 
1 216 VAL n 
1 217 VAL n 
1 218 ALA n 
1 219 LEU n 
1 220 THR n 
1 221 ALA n 
1 222 GLY n 
1 223 LEU n 
1 224 GLY n 
1 225 SER n 
1 226 GLY n 
1 227 ILE n 
1 228 PRO n 
1 229 VAL n 
1 230 GLY n 
1 231 LYS n 
1 232 GLU n 
1 233 GLY n 
1 234 PRO n 
1 235 PHE n 
1 236 VAL n 
1 237 HIS n 
1 238 ILE n 
1 239 ALA n 
1 240 SER n 
1 241 ILE n 
1 242 CYS n 
1 243 ALA n 
1 244 ALA n 
1 245 VAL n 
1 246 LEU n 
1 247 SER n 
1 248 LYS n 
1 249 PHE n 
1 250 MET n 
1 251 SER n 
1 252 VAL n 
1 253 PHE n 
1 254 CYS n 
1 255 GLY n 
1 256 VAL n 
1 257 TYR n 
1 258 GLU n 
1 259 GLN n 
1 260 PRO n 
1 261 TYR n 
1 262 TYR n 
1 263 TYR n 
1 264 SER n 
1 265 ASP n 
1 266 ILE n 
1 267 LEU n 
1 268 THR n 
1 269 VAL n 
1 270 GLY n 
1 271 CYS n 
1 272 ALA n 
1 273 VAL n 
1 274 GLY n 
1 275 VAL n 
1 276 GLY n 
1 277 CYS n 
1 278 CYS n 
1 279 PHE n 
1 280 GLY n 
1 281 THR n 
1 282 PRO n 
1 283 LEU n 
1 284 GLY n 
1 285 GLY n 
1 286 VAL n 
1 287 LEU n 
1 288 PHE n 
1 289 SER n 
1 290 ILE n 
1 291 GLU n 
1 292 VAL n 
1 293 THR n 
1 294 SER n 
1 295 THR n 
1 296 TYR n 
1 297 PHE n 
1 298 ALA n 
1 299 VAL n 
1 300 ARG n 
1 301 ASN n 
1 302 TYR n 
1 303 TRP n 
1 304 ARG n 
1 305 GLY n 
1 306 PHE n 
1 307 PHE n 
1 308 ALA n 
1 309 ALA n 
1 310 THR n 
1 311 PHE n 
1 312 SER n 
1 313 ALA n 
1 314 PHE n 
1 315 VAL n 
1 316 PHE n 
1 317 ARG n 
1 318 VAL n 
1 319 LEU n 
1 320 ALA n 
1 321 VAL n 
1 322 TRP n 
1 323 ASN n 
1 324 LYS n 
1 325 ASP n 
1 326 ALA n 
1 327 VAL n 
1 328 THR n 
1 329 ILE n 
1 330 THR n 
1 331 ALA n 
1 332 LEU n 
1 333 PHE n 
1 334 ARG n 
1 335 THR n 
1 336 ASN n 
1 337 PHE n 
1 338 ARG n 
1 339 MET n 
1 340 ASP n 
1 341 PHE n 
1 342 PRO n 
1 343 PHE n 
1 344 ASP n 
1 345 LEU n 
1 346 LYS n 
1 347 GLU n 
1 348 LEU n 
1 349 PRO n 
1 350 ALA n 
1 351 PHE n 
1 352 ALA n 
1 353 ALA n 
1 354 ILE n 
1 355 GLY n 
1 356 ILE n 
1 357 CYS n 
1 358 CYS n 
1 359 GLY n 
1 360 LEU n 
1 361 LEU n 
1 362 GLY n 
1 363 ALA n 
1 364 VAL n 
1 365 PHE n 
1 366 VAL n 
1 367 TYR n 
1 368 LEU n 
1 369 HIS n 
1 370 ARG n 
1 371 GLN n 
1 372 VAL n 
1 373 MET n 
1 374 LEU n 
1 375 GLY n 
1 376 VAL n 
1 377 ARG n 
1 378 LYS n 
1 379 HIS n 
1 380 LYS n 
1 381 ALA n 
1 382 LEU n 
1 383 SER n 
1 384 GLN n 
1 385 PHE n 
1 386 LEU n 
1 387 ALA n 
1 388 LYS n 
1 389 HIS n 
1 390 ARG n 
1 391 LEU n 
1 392 LEU n 
1 393 TYR n 
1 394 PRO n 
1 395 GLY n 
1 396 ILE n 
1 397 VAL n 
1 398 THR n 
1 399 PHE n 
1 400 VAL n 
1 401 ILE n 
1 402 ALA n 
1 403 SER n 
1 404 PHE n 
1 405 THR n 
1 406 PHE n 
1 407 PRO n 
1 408 PRO n 
1 409 GLY n 
1 410 MET n 
1 411 GLY n 
1 412 GLN n 
1 413 PHE n 
1 414 MET n 
1 415 ALA n 
1 416 GLY n 
1 417 GLU n 
1 418 LEU n 
1 419 MET n 
1 420 PRO n 
1 421 ARG n 
1 422 GLU n 
1 423 ALA n 
1 424 ILE n 
1 425 SER n 
1 426 THR n 
1 427 LEU n 
1 428 PHE n 
1 429 ASP n 
1 430 ASN n 
1 431 ASN n 
1 432 THR n 
1 433 TRP n 
1 434 VAL n 
1 435 LYS n 
1 436 HIS n 
1 437 ALA n 
1 438 GLY n 
1 439 ASP n 
1 440 PRO n 
1 441 GLU n 
1 442 SER n 
1 443 LEU n 
1 444 GLY n 
1 445 GLN n 
1 446 SER n 
1 447 ALA n 
1 448 VAL n 
1 449 TRP n 
1 450 ILE n 
1 451 HIS n 
1 452 PRO n 
1 453 ARG n 
1 454 VAL n 
1 455 ASN n 
1 456 VAL n 
1 457 VAL n 
1 458 ILE n 
1 459 ILE n 
1 460 ILE n 
1 461 PHE n 
1 462 LEU n 
1 463 PHE n 
1 464 PHE n 
1 465 VAL n 
1 466 MET n 
1 467 LYS n 
1 468 PHE n 
1 469 TRP n 
1 470 MET n 
1 471 SER n 
1 472 ILE n 
1 473 VAL n 
1 474 ALA n 
1 475 THR n 
1 476 THR n 
1 477 MET n 
1 478 PRO n 
1 479 ILE n 
1 480 PRO n 
1 481 CYS n 
1 482 GLY n 
1 483 GLY n 
1 484 PHE n 
1 485 MET n 
1 486 PRO n 
1 487 VAL n 
1 488 PHE n 
1 489 VAL n 
1 490 LEU n 
1 491 GLY n 
1 492 ALA n 
1 493 ALA n 
1 494 PHE n 
1 495 GLY n 
1 496 ARG n 
1 497 LEU n 
1 498 VAL n 
1 499 GLY n 
1 500 GLU n 
1 501 ILE n 
1 502 MET n 
1 503 ALA n 
1 504 MET n 
1 505 LEU n 
1 506 PHE n 
1 507 PRO n 
1 508 ASP n 
1 509 GLY n 
1 510 ILE n 
1 511 LEU n 
1 512 PHE n 
1 513 ASP n 
1 514 ASP n 
1 515 ILE n 
1 516 ILE n 
1 517 TYR n 
1 518 LYS n 
1 519 ILE n 
1 520 LEU n 
1 521 PRO n 
1 522 GLY n 
1 523 GLY n 
1 524 TYR n 
1 525 ALA n 
1 526 VAL n 
1 527 ILE n 
1 528 GLY n 
1 529 ALA n 
1 530 ALA n 
1 531 ALA n 
1 532 LEU n 
1 533 THR n 
1 534 GLY n 
1 535 ALA n 
1 536 VAL n 
1 537 SER n 
1 538 HIS n 
1 539 THR n 
1 540 VAL n 
1 541 SER n 
1 542 THR n 
1 543 ALA n 
1 544 VAL n 
1 545 ILE n 
1 546 CYS n 
1 547 PHE n 
1 548 GLU n 
1 549 LEU n 
1 550 THR n 
1 551 GLY n 
1 552 GLN n 
1 553 ILE n 
1 554 ALA n 
1 555 HIS n 
1 556 ILE n 
1 557 LEU n 
1 558 PRO n 
1 559 MET n 
1 560 MET n 
1 561 VAL n 
1 562 ALA n 
1 563 VAL n 
1 564 ILE n 
1 565 LEU n 
1 566 ALA n 
1 567 ASN n 
1 568 MET n 
1 569 VAL n 
1 570 ALA n 
1 571 GLN n 
1 572 SER n 
1 573 LEU n 
1 574 GLN n 
1 575 PRO n 
1 576 SER n 
1 577 LEU n 
1 578 TYR n 
1 579 ASP n 
1 580 SER n 
1 581 ILE n 
1 582 ILE n 
1 583 GLN n 
1 584 VAL n 
1 585 LYS n 
1 586 LYS n 
1 587 LEU n 
1 588 PRO n 
1 589 TYR n 
1 590 LEU n 
1 591 PRO n 
1 592 ASP n 
1 593 LEU n 
1 594 GLY n 
1 595 TRP n 
1 596 ASN n 
1 597 GLN n 
1 598 LEU n 
1 599 SER n 
1 600 LYS n 
1 601 TYR n 
1 602 THR n 
1 603 ILE n 
1 604 PHE n 
1 605 VAL n 
1 606 GLU n 
1 607 ASP n 
1 608 ILE n 
1 609 MET n 
1 610 VAL n 
1 611 ARG n 
1 612 ASP n 
1 613 VAL n 
1 614 LYS n 
1 615 PHE n 
1 616 VAL n 
1 617 SER n 
1 618 ALA n 
1 619 SER n 
1 620 TYR n 
1 621 THR n 
1 622 TYR n 
1 623 GLY n 
1 624 GLU n 
1 625 LEU n 
1 626 ARG n 
1 627 THR n 
1 628 LEU n 
1 629 LEU n 
1 630 GLN n 
1 631 THR n 
1 632 THR n 
1 633 THR n 
1 634 VAL n 
1 635 LYS n 
1 636 THR n 
1 637 LEU n 
1 638 PRO n 
1 639 LEU n 
1 640 VAL n 
1 641 ASP n 
1 642 SER n 
1 643 LYS n 
1 644 ASP n 
1 645 SER n 
1 646 MET n 
1 647 ILE n 
1 648 LEU n 
1 649 LEU n 
1 650 GLY n 
1 651 SER n 
1 652 VAL n 
1 653 GLU n 
1 654 ARG n 
1 655 SER n 
1 656 GLU n 
1 657 LEU n 
1 658 GLN n 
1 659 ALA n 
1 660 LEU n 
1 661 LEU n 
1 662 GLN n 
1 663 ARG n 
1 664 HIS n 
1 665 LEU n 
1 666 CYS n 
1 667 PRO n 
1 668 GLU n 
1 669 ARG n 
1 670 ARG n 
1 671 LEU n 
1 672 ARG n 
1 673 ALA n 
1 674 ALA n 
1 675 GLN n 
1 676 GLU n 
1 677 MET n 
1 678 ALA n 
1 679 ARG n 
1 680 LYS n 
1 681 LEU n 
1 682 SER n 
1 683 GLU n 
1 684 LEU n 
1 685 PRO n 
1 686 TYR n 
1 687 ASP n 
1 688 GLY n 
1 689 LYS n 
1 690 ALA n 
1 691 ARG n 
1 692 LEU n 
1 693 ALA n 
1 694 GLY n 
1 695 GLU n 
1 696 GLY n 
1 697 LEU n 
1 698 PRO n 
1 699 GLY n 
1 700 ALA n 
1 701 PRO n 
1 702 PRO n 
1 703 GLY n 
1 704 ARG n 
1 705 PRO n 
1 706 GLU n 
1 707 SER n 
1 708 PHE n 
1 709 ALA n 
1 710 PHE n 
1 711 VAL n 
1 712 ASP n 
1 713 GLU n 
1 714 ASP n 
1 715 GLU n 
1 716 ASP n 
1 717 GLU n 
1 718 ASP n 
1 719 LEU n 
1 720 SER n 
1 721 GLY n 
1 722 LYS n 
1 723 SER n 
1 724 GLU n 
1 725 LEU n 
1 726 PRO n 
1 727 PRO n 
1 728 SER n 
1 729 LEU n 
1 730 ALA n 
1 731 LEU n 
1 732 HIS n 
1 733 PRO n 
1 734 SER n 
1 735 THR n 
1 736 THR n 
1 737 ALA n 
1 738 PRO n 
1 739 LEU n 
1 740 SER n 
1 741 PRO n 
1 742 GLU n 
1 743 GLU n 
1 744 PRO n 
1 745 ASN n 
1 746 GLY n 
1 747 PRO n 
1 748 LEU n 
1 749 PRO n 
1 750 GLY n 
1 751 HIS n 
1 752 LYS n 
1 753 GLN n 
1 754 GLN n 
1 755 PRO n 
1 756 GLU n 
1 757 ALA n 
1 758 PRO n 
1 759 GLU n 
1 760 PRO n 
1 761 ALA n 
1 762 GLY n 
1 763 GLN n 
1 764 ARG n 
1 765 PRO n 
1 766 SER n 
1 767 ILE n 
1 768 PHE n 
1 769 GLN n 
1 770 SER n 
1 771 LEU n 
1 772 LEU n 
1 773 HIS n 
1 774 CYS n 
1 775 LEU n 
1 776 LEU n 
1 777 GLY n 
1 778 ARG n 
1 779 ALA n 
1 780 ARG n 
1 781 PRO n 
1 782 THR n 
1 783 LYS n 
1 784 LYS n 
1 785 LYS n 
1 786 THR n 
1 787 THR n 
1 788 GLN n 
1 789 ASP n 
1 790 SER n 
1 791 THR n 
1 792 ASP n 
1 793 LEU n 
1 794 VAL n 
1 795 ASP n 
1 796 ASN n 
1 797 MET n 
1 798 SER n 
1 799 PRO n 
1 800 GLU n 
1 801 GLU n 
1 802 ILE n 
1 803 GLU n 
1 804 ALA n 
1 805 TRP n 
1 806 GLU n 
1 807 GLN n 
1 808 GLU n 
1 809 GLN n 
1 810 LEU n 
1 811 SER n 
1 812 GLN n 
1 813 PRO n 
1 814 VAL n 
1 815 CYS n 
1 816 PHE n 
1 817 ASP n 
1 818 SER n 
1 819 CYS n 
1 820 CYS n 
1 821 ILE n 
1 822 ASP n 
1 823 GLN n 
1 824 SER n 
1 825 PRO n 
1 826 PHE n 
1 827 GLN n 
1 828 LEU n 
1 829 VAL n 
1 830 GLU n 
1 831 GLN n 
1 832 THR n 
1 833 THR n 
1 834 LEU n 
1 835 HIS n 
1 836 LYS n 
1 837 THR n 
1 838 HIS n 
1 839 THR n 
1 840 LEU n 
1 841 PHE n 
1 842 SER n 
1 843 LEU n 
1 844 LEU n 
1 845 GLY n 
1 846 LEU n 
1 847 HIS n 
1 848 LEU n 
1 849 ALA n 
1 850 TYR n 
1 851 VAL n 
1 852 THR n 
1 853 SER n 
1 854 MET n 
1 855 GLY n 
1 856 LYS n 
1 857 LEU n 
1 858 ARG n 
1 859 GLY n 
1 860 VAL n 
1 861 LEU n 
1 862 ALA n 
1 863 LEU n 
1 864 GLU n 
1 865 GLU n 
1 866 LEU n 
1 867 GLN n 
1 868 LYS n 
1 869 ALA n 
1 870 ILE n 
1 871 GLU n 
1 872 GLY n 
1 873 HIS n 
1 874 THR n 
1 875 LYS n 
1 876 SER n 
1 877 GLY n 
1 878 VAL n 
1 879 GLN n 
1 880 LEU n 
1 881 ARG n 
1 882 PRO n 
1 883 PRO n 
1 884 LEU n 
1 885 ALA n 
1 886 SER n 
1 887 PHE n 
1 888 ARG n 
1 889 ASN n 
1 890 THR n 
1 891 THR n 
1 892 SER n 
1 893 THR n 
1 894 ARG n 
1 895 LYS n 
1 896 SER n 
1 897 THR n 
1 898 GLY n 
1 899 ALA n 
1 900 PRO n 
1 901 PRO n 
1 902 SER n 
1 903 SER n 
1 904 ALA n 
1 905 GLU n 
1 906 ASN n 
1 907 TRP n 
1 908 ASN n 
1 909 LEU n 
1 910 PRO n 
1 911 GLU n 
1 912 ASP n 
1 913 ARG n 
1 914 PRO n 
1 915 GLY n 
1 916 ALA n 
1 917 THR n 
1 918 GLY n 
1 919 THR n 
1 920 GLY n 
1 921 ASP n 
1 922 VAL n 
1 923 ILE n 
1 924 ALA n 
1 925 ALA n 
1 926 SER n 
1 927 PRO n 
1 928 GLU n 
1 929 THR n 
1 930 PRO n 
1 931 VAL n 
1 932 PRO n 
1 933 SER n 
1 934 PRO n 
1 935 SER n 
1 936 PRO n 
1 937 GLU n 
1 938 PRO n 
1 939 PRO n 
1 940 LEU n 
1 941 SER n 
1 942 LEU n 
1 943 ALA n 
1 944 PRO n 
1 945 GLY n 
1 946 LYS n 
1 947 VAL n 
1 948 GLU n 
1 949 GLY n 
1 950 GLU n 
1 951 LEU n 
1 952 GLU n 
1 953 GLU n 
1 954 LEU n 
1 955 GLU n 
1 956 LEU n 
1 957 VAL n 
1 958 GLU n 
1 959 SER n 
1 960 PRO n 
1 961 GLY n 
1 962 LEU n 
1 963 GLU n 
1 964 GLU n 
1 965 GLU n 
1 966 LEU n 
1 967 ALA n 
1 968 ASP n 
1 969 ILE n 
1 970 LEU n 
1 971 GLN n 
1 972 GLY n 
1 973 PRO n 
1 974 SER n 
1 975 LEU n 
1 976 ARG n 
1 977 SER n 
1 978 THR n 
1 979 ASP n 
1 980 GLU n 
1 981 GLU n 
1 982 ASP n 
1 983 GLU n 
1 984 ASP n 
1 985 GLU n 
1 986 LEU n 
1 987 ILE n 
1 988 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   988 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 CLCN1 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE           ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE          ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE        ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'   ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE          ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE         ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'   ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE           ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE         ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE        ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE           ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE            ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE        ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE     ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE           ? 'C5 H9 N O2'     115.130 
SCN non-polymer         . 'THIOCYANATE ION' ? 'C N S -1'       58.082  
SER 'L-peptide linking' y SERINE            ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE         ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN        ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE          ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE            ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLU 2   2   ?   ?   ?   A . n 
A 1 3   GLN 3   3   ?   ?   ?   A . n 
A 1 4   SER 4   4   ?   ?   ?   A . n 
A 1 5   ARG 5   5   ?   ?   ?   A . n 
A 1 6   SER 6   6   ?   ?   ?   A . n 
A 1 7   GLN 7   7   ?   ?   ?   A . n 
A 1 8   GLN 8   8   ?   ?   ?   A . n 
A 1 9   ARG 9   9   ?   ?   ?   A . n 
A 1 10  GLY 10  10  ?   ?   ?   A . n 
A 1 11  GLY 11  11  ?   ?   ?   A . n 
A 1 12  GLU 12  12  ?   ?   ?   A . n 
A 1 13  GLN 13  13  ?   ?   ?   A . n 
A 1 14  SER 14  14  ?   ?   ?   A . n 
A 1 15  TRP 15  15  ?   ?   ?   A . n 
A 1 16  TRP 16  16  ?   ?   ?   A . n 
A 1 17  GLY 17  17  ?   ?   ?   A . n 
A 1 18  SER 18  18  ?   ?   ?   A . n 
A 1 19  ASP 19  19  ?   ?   ?   A . n 
A 1 20  PRO 20  20  ?   ?   ?   A . n 
A 1 21  GLN 21  21  ?   ?   ?   A . n 
A 1 22  TYR 22  22  ?   ?   ?   A . n 
A 1 23  GLN 23  23  ?   ?   ?   A . n 
A 1 24  TYR 24  24  ?   ?   ?   A . n 
A 1 25  MET 25  25  ?   ?   ?   A . n 
A 1 26  PRO 26  26  ?   ?   ?   A . n 
A 1 27  PHE 27  27  ?   ?   ?   A . n 
A 1 28  GLU 28  28  ?   ?   ?   A . n 
A 1 29  HIS 29  29  ?   ?   ?   A . n 
A 1 30  CYS 30  30  ?   ?   ?   A . n 
A 1 31  THR 31  31  ?   ?   ?   A . n 
A 1 32  SER 32  32  ?   ?   ?   A . n 
A 1 33  TYR 33  33  ?   ?   ?   A . n 
A 1 34  GLY 34  34  ?   ?   ?   A . n 
A 1 35  LEU 35  35  ?   ?   ?   A . n 
A 1 36  PRO 36  36  ?   ?   ?   A . n 
A 1 37  SER 37  37  ?   ?   ?   A . n 
A 1 38  GLU 38  38  ?   ?   ?   A . n 
A 1 39  ASN 39  39  ?   ?   ?   A . n 
A 1 40  GLY 40  40  ?   ?   ?   A . n 
A 1 41  GLY 41  41  ?   ?   ?   A . n 
A 1 42  LEU 42  42  ?   ?   ?   A . n 
A 1 43  GLN 43  43  ?   ?   ?   A . n 
A 1 44  HIS 44  44  ?   ?   ?   A . n 
A 1 45  ARG 45  45  ?   ?   ?   A . n 
A 1 46  LEU 46  46  ?   ?   ?   A . n 
A 1 47  ARG 47  47  ?   ?   ?   A . n 
A 1 48  LYS 48  48  ?   ?   ?   A . n 
A 1 49  ASP 49  49  ?   ?   ?   A . n 
A 1 50  ALA 50  50  ?   ?   ?   A . n 
A 1 51  GLY 51  51  ?   ?   ?   A . n 
A 1 52  PRO 52  52  ?   ?   ?   A . n 
A 1 53  ARG 53  53  ?   ?   ?   A . n 
A 1 54  HIS 54  54  ?   ?   ?   A . n 
A 1 55  ASN 55  55  ?   ?   ?   A . n 
A 1 56  VAL 56  56  ?   ?   ?   A . n 
A 1 57  HIS 57  57  ?   ?   ?   A . n 
A 1 58  PRO 58  58  ?   ?   ?   A . n 
A 1 59  THR 59  59  ?   ?   ?   A . n 
A 1 60  GLN 60  60  ?   ?   ?   A . n 
A 1 61  ILE 61  61  ?   ?   ?   A . n 
A 1 62  TYR 62  62  ?   ?   ?   A . n 
A 1 63  GLY 63  63  ?   ?   ?   A . n 
A 1 64  HIS 64  64  ?   ?   ?   A . n 
A 1 65  HIS 65  65  ?   ?   ?   A . n 
A 1 66  LYS 66  66  ?   ?   ?   A . n 
A 1 67  GLU 67  67  ?   ?   ?   A . n 
A 1 68  GLN 68  68  ?   ?   ?   A . n 
A 1 69  PHE 69  69  ?   ?   ?   A . n 
A 1 70  SER 70  70  ?   ?   ?   A . n 
A 1 71  ASP 71  71  ?   ?   ?   A . n 
A 1 72  ARG 72  72  ?   ?   ?   A . n 
A 1 73  GLU 73  73  ?   ?   ?   A . n 
A 1 74  GLN 74  74  ?   ?   ?   A . n 
A 1 75  ASP 75  75  ?   ?   ?   A . n 
A 1 76  ILE 76  76  ?   ?   ?   A . n 
A 1 77  GLY 77  77  ?   ?   ?   A . n 
A 1 78  MET 78  78  ?   ?   ?   A . n 
A 1 79  PRO 79  79  ?   ?   ?   A . n 
A 1 80  LYS 80  80  ?   ?   ?   A . n 
A 1 81  LYS 81  81  ?   ?   ?   A . n 
A 1 82  THR 82  82  ?   ?   ?   A . n 
A 1 83  GLY 83  83  ?   ?   ?   A . n 
A 1 84  SER 84  84  ?   ?   ?   A . n 
A 1 85  SER 85  85  ?   ?   ?   A . n 
A 1 86  SER 86  86  ?   ?   ?   A . n 
A 1 87  THR 87  87  ?   ?   ?   A . n 
A 1 88  VAL 88  88  ?   ?   ?   A . n 
A 1 89  ASP 89  89  ?   ?   ?   A . n 
A 1 90  SER 90  90  ?   ?   ?   A . n 
A 1 91  LYS 91  91  ?   ?   ?   A . n 
A 1 92  ASP 92  92  ?   ?   ?   A . n 
A 1 93  GLU 93  93  ?   ?   ?   A . n 
A 1 94  ASP 94  94  ?   ?   ?   A . n 
A 1 95  HIS 95  95  ?   ?   ?   A . n 
A 1 96  TYR 96  96  ?   ?   ?   A . n 
A 1 97  SER 97  97  ?   ?   ?   A . n 
A 1 98  LYS 98  98  ?   ?   ?   A . n 
A 1 99  CYS 99  99  ?   ?   ?   A . n 
A 1 100 GLN 100 100 ?   ?   ?   A . n 
A 1 101 ASP 101 101 ?   ?   ?   A . n 
A 1 102 CYS 102 102 ?   ?   ?   A . n 
A 1 103 ILE 103 103 ?   ?   ?   A . n 
A 1 104 HIS 104 104 ?   ?   ?   A . n 
A 1 105 ARG 105 105 ?   ?   ?   A . n 
A 1 106 LEU 106 106 ?   ?   ?   A . n 
A 1 107 GLY 107 107 ?   ?   ?   A . n 
A 1 108 GLN 108 108 ?   ?   ?   A . n 
A 1 109 VAL 109 109 ?   ?   ?   A . n 
A 1 110 VAL 110 110 ?   ?   ?   A . n 
A 1 111 ARG 111 111 ?   ?   ?   A . n 
A 1 112 ARG 112 112 ?   ?   ?   A . n 
A 1 113 LYS 113 113 ?   ?   ?   A . n 
A 1 114 LEU 114 114 ?   ?   ?   A . n 
A 1 115 GLY 115 115 115 GLY GLY A . n 
A 1 116 GLU 116 116 116 GLU GLU A . n 
A 1 117 ASP 117 117 117 ASP ASP A . n 
A 1 118 GLY 118 118 118 GLY GLY A . n 
A 1 119 ILE 119 119 119 ILE ILE A . n 
A 1 120 PHE 120 120 120 PHE PHE A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 VAL 122 122 122 VAL VAL A . n 
A 1 123 LEU 123 123 123 LEU LEU A . n 
A 1 124 LEU 124 124 124 LEU LEU A . n 
A 1 125 GLY 125 125 125 GLY GLY A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 LEU 127 127 127 LEU LEU A . n 
A 1 128 MET 128 128 128 MET MET A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 LEU 130 130 130 LEU LEU A . n 
A 1 131 VAL 131 131 131 VAL VAL A . n 
A 1 132 SER 132 132 132 SER SER A . n 
A 1 133 TRP 133 133 133 TRP TRP A . n 
A 1 134 SER 134 134 134 SER SER A . n 
A 1 135 MET 135 135 135 MET MET A . n 
A 1 136 GLY 136 136 136 GLY GLY A . n 
A 1 137 TYR 137 137 137 TYR TYR A . n 
A 1 138 VAL 138 138 138 VAL VAL A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 LYS 141 141 141 LYS LYS A . n 
A 1 142 SER 142 142 142 SER SER A . n 
A 1 143 LEU 143 143 143 LEU LEU A . n 
A 1 144 GLN 144 144 144 GLN GLN A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 TYR 146 146 146 TYR TYR A . n 
A 1 147 LYS 147 147 147 LYS LYS A . n 
A 1 148 TRP 148 148 148 TRP TRP A . n 
A 1 149 SER 149 149 149 SER SER A . n 
A 1 150 TYR 150 150 150 TYR TYR A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 GLN 152 152 152 GLN GLN A . n 
A 1 153 MET 153 153 153 MET MET A . n 
A 1 154 GLN 154 154 154 GLN GLN A . n 
A 1 155 PRO 155 155 155 PRO PRO A . n 
A 1 156 SER 156 156 156 SER SER A . n 
A 1 157 LEU 157 157 157 LEU LEU A . n 
A 1 158 PRO 158 158 158 PRO PRO A . n 
A 1 159 LEU 159 159 159 LEU LEU A . n 
A 1 160 GLN 160 160 160 GLN GLN A . n 
A 1 161 PHE 161 161 161 PHE PHE A . n 
A 1 162 LEU 162 162 162 LEU LEU A . n 
A 1 163 VAL 163 163 163 VAL VAL A . n 
A 1 164 TRP 164 164 164 TRP TRP A . n 
A 1 165 VAL 165 165 165 VAL VAL A . n 
A 1 166 THR 166 166 166 THR THR A . n 
A 1 167 PHE 167 167 167 PHE PHE A . n 
A 1 168 PRO 168 168 168 PRO PRO A . n 
A 1 169 LEU 169 169 169 LEU LEU A . n 
A 1 170 VAL 170 170 170 VAL VAL A . n 
A 1 171 LEU 171 171 171 LEU LEU A . n 
A 1 172 ILE 172 172 172 ILE ILE A . n 
A 1 173 LEU 173 173 173 LEU LEU A . n 
A 1 174 PHE 174 174 174 PHE PHE A . n 
A 1 175 SER 175 175 175 SER SER A . n 
A 1 176 ALA 176 176 176 ALA ALA A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 PHE 178 178 178 PHE PHE A . n 
A 1 179 CYS 179 179 179 CYS CYS A . n 
A 1 180 HIS 180 180 180 HIS HIS A . n 
A 1 181 LEU 181 181 181 LEU LEU A . n 
A 1 182 ILE 182 182 182 ILE ILE A . n 
A 1 183 SER 183 183 183 SER SER A . n 
A 1 184 PRO 184 184 184 PRO PRO A . n 
A 1 185 GLN 185 185 185 GLN GLN A . n 
A 1 186 ALA 186 186 186 ALA ALA A . n 
A 1 187 VAL 187 187 187 VAL VAL A . n 
A 1 188 GLY 188 188 188 GLY GLY A . n 
A 1 189 SER 189 189 189 SER SER A . n 
A 1 190 GLY 190 190 190 GLY GLY A . n 
A 1 191 ILE 191 191 191 ILE ILE A . n 
A 1 192 PRO 192 192 192 PRO PRO A . n 
A 1 193 GLU 193 193 193 GLU GLU A . n 
A 1 194 MET 194 194 194 MET MET A . n 
A 1 195 LYS 195 195 195 LYS LYS A . n 
A 1 196 THR 196 196 196 THR THR A . n 
A 1 197 ILE 197 197 197 ILE ILE A . n 
A 1 198 LEU 198 198 198 LEU LEU A . n 
A 1 199 ARG 199 199 199 ARG ARG A . n 
A 1 200 GLY 200 200 200 GLY GLY A . n 
A 1 201 VAL 201 201 201 VAL VAL A . n 
A 1 202 VAL 202 202 202 VAL VAL A . n 
A 1 203 LEU 203 203 203 LEU LEU A . n 
A 1 204 LYS 204 204 204 LYS LYS A . n 
A 1 205 GLU 205 205 205 GLU GLU A . n 
A 1 206 TYR 206 206 206 TYR TYR A . n 
A 1 207 LEU 207 207 207 LEU LEU A . n 
A 1 208 THR 208 208 208 THR THR A . n 
A 1 209 MET 209 209 209 MET MET A . n 
A 1 210 LYS 210 210 210 LYS LYS A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 PHE 212 212 212 PHE PHE A . n 
A 1 213 VAL 213 213 213 VAL VAL A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 LYS 215 215 215 LYS LYS A . n 
A 1 216 VAL 216 216 216 VAL VAL A . n 
A 1 217 VAL 217 217 217 VAL VAL A . n 
A 1 218 ALA 218 218 218 ALA ALA A . n 
A 1 219 LEU 219 219 219 LEU LEU A . n 
A 1 220 THR 220 220 220 THR THR A . n 
A 1 221 ALA 221 221 221 ALA ALA A . n 
A 1 222 GLY 222 222 222 GLY GLY A . n 
A 1 223 LEU 223 223 223 LEU LEU A . n 
A 1 224 GLY 224 224 224 GLY GLY A . n 
A 1 225 SER 225 225 225 SER SER A . n 
A 1 226 GLY 226 226 226 GLY GLY A . n 
A 1 227 ILE 227 227 227 ILE ILE A . n 
A 1 228 PRO 228 228 228 PRO PRO A . n 
A 1 229 VAL 229 229 229 VAL VAL A . n 
A 1 230 GLY 230 230 230 GLY GLY A . n 
A 1 231 LYS 231 231 231 LYS LYS A . n 
A 1 232 GLU 232 232 232 GLU GLU A . n 
A 1 233 GLY 233 233 233 GLY GLY A . n 
A 1 234 PRO 234 234 234 PRO PRO A . n 
A 1 235 PHE 235 235 235 PHE PHE A . n 
A 1 236 VAL 236 236 236 VAL VAL A . n 
A 1 237 HIS 237 237 237 HIS HIS A . n 
A 1 238 ILE 238 238 238 ILE ILE A . n 
A 1 239 ALA 239 239 239 ALA ALA A . n 
A 1 240 SER 240 240 240 SER SER A . n 
A 1 241 ILE 241 241 241 ILE ILE A . n 
A 1 242 CYS 242 242 242 CYS CYS A . n 
A 1 243 ALA 243 243 243 ALA ALA A . n 
A 1 244 ALA 244 244 244 ALA ALA A . n 
A 1 245 VAL 245 245 245 VAL VAL A . n 
A 1 246 LEU 246 246 246 LEU LEU A . n 
A 1 247 SER 247 247 247 SER SER A . n 
A 1 248 LYS 248 248 248 LYS LYS A . n 
A 1 249 PHE 249 249 249 PHE PHE A . n 
A 1 250 MET 250 250 250 MET MET A . n 
A 1 251 SER 251 251 251 SER SER A . n 
A 1 252 VAL 252 252 252 VAL VAL A . n 
A 1 253 PHE 253 253 253 PHE PHE A . n 
A 1 254 CYS 254 254 ?   ?   ?   A . n 
A 1 255 GLY 255 255 ?   ?   ?   A . n 
A 1 256 VAL 256 256 ?   ?   ?   A . n 
A 1 257 TYR 257 257 ?   ?   ?   A . n 
A 1 258 GLU 258 258 ?   ?   ?   A . n 
A 1 259 GLN 259 259 ?   ?   ?   A . n 
A 1 260 PRO 260 260 ?   ?   ?   A . n 
A 1 261 TYR 261 261 ?   ?   ?   A . n 
A 1 262 TYR 262 262 262 TYR TYR A . n 
A 1 263 TYR 263 263 263 TYR TYR A . n 
A 1 264 SER 264 264 264 SER SER A . n 
A 1 265 ASP 265 265 265 ASP ASP A . n 
A 1 266 ILE 266 266 266 ILE ILE A . n 
A 1 267 LEU 267 267 267 LEU LEU A . n 
A 1 268 THR 268 268 268 THR THR A . n 
A 1 269 VAL 269 269 269 VAL VAL A . n 
A 1 270 GLY 270 270 270 GLY GLY A . n 
A 1 271 CYS 271 271 271 CYS CYS A . n 
A 1 272 ALA 272 272 272 ALA ALA A . n 
A 1 273 VAL 273 273 273 VAL VAL A . n 
A 1 274 GLY 274 274 274 GLY GLY A . n 
A 1 275 VAL 275 275 275 VAL VAL A . n 
A 1 276 GLY 276 276 276 GLY GLY A . n 
A 1 277 CYS 277 277 277 CYS CYS A . n 
A 1 278 CYS 278 278 278 CYS CYS A . n 
A 1 279 PHE 279 279 279 PHE PHE A . n 
A 1 280 GLY 280 280 280 GLY GLY A . n 
A 1 281 THR 281 281 281 THR THR A . n 
A 1 282 PRO 282 282 282 PRO PRO A . n 
A 1 283 LEU 283 283 283 LEU LEU A . n 
A 1 284 GLY 284 284 284 GLY GLY A . n 
A 1 285 GLY 285 285 285 GLY GLY A . n 
A 1 286 VAL 286 286 286 VAL VAL A . n 
A 1 287 LEU 287 287 287 LEU LEU A . n 
A 1 288 PHE 288 288 288 PHE PHE A . n 
A 1 289 SER 289 289 289 SER SER A . n 
A 1 290 ILE 290 290 290 ILE ILE A . n 
A 1 291 GLU 291 291 291 GLU GLU A . n 
A 1 292 VAL 292 292 292 VAL VAL A . n 
A 1 293 THR 293 293 293 THR THR A . n 
A 1 294 SER 294 294 294 SER SER A . n 
A 1 295 THR 295 295 295 THR THR A . n 
A 1 296 TYR 296 296 296 TYR TYR A . n 
A 1 297 PHE 297 297 297 PHE PHE A . n 
A 1 298 ALA 298 298 298 ALA ALA A . n 
A 1 299 VAL 299 299 299 VAL VAL A . n 
A 1 300 ARG 300 300 300 ARG ARG A . n 
A 1 301 ASN 301 301 301 ASN ASN A . n 
A 1 302 TYR 302 302 302 TYR TYR A . n 
A 1 303 TRP 303 303 303 TRP TRP A . n 
A 1 304 ARG 304 304 304 ARG ARG A . n 
A 1 305 GLY 305 305 305 GLY GLY A . n 
A 1 306 PHE 306 306 306 PHE PHE A . n 
A 1 307 PHE 307 307 307 PHE PHE A . n 
A 1 308 ALA 308 308 308 ALA ALA A . n 
A 1 309 ALA 309 309 309 ALA ALA A . n 
A 1 310 THR 310 310 310 THR THR A . n 
A 1 311 PHE 311 311 311 PHE PHE A . n 
A 1 312 SER 312 312 312 SER SER A . n 
A 1 313 ALA 313 313 313 ALA ALA A . n 
A 1 314 PHE 314 314 314 PHE PHE A . n 
A 1 315 VAL 315 315 315 VAL VAL A . n 
A 1 316 PHE 316 316 316 PHE PHE A . n 
A 1 317 ARG 317 317 317 ARG ARG A . n 
A 1 318 VAL 318 318 318 VAL VAL A . n 
A 1 319 LEU 319 319 319 LEU LEU A . n 
A 1 320 ALA 320 320 320 ALA ALA A . n 
A 1 321 VAL 321 321 321 VAL VAL A . n 
A 1 322 TRP 322 322 322 TRP TRP A . n 
A 1 323 ASN 323 323 323 ASN ASN A . n 
A 1 324 LYS 324 324 324 LYS LYS A . n 
A 1 325 ASP 325 325 325 ASP ASP A . n 
A 1 326 ALA 326 326 326 ALA ALA A . n 
A 1 327 VAL 327 327 327 VAL VAL A . n 
A 1 328 THR 328 328 328 THR THR A . n 
A 1 329 ILE 329 329 329 ILE ILE A . n 
A 1 330 THR 330 330 330 THR THR A . n 
A 1 331 ALA 331 331 331 ALA ALA A . n 
A 1 332 LEU 332 332 332 LEU LEU A . n 
A 1 333 PHE 333 333 333 PHE PHE A . n 
A 1 334 ARG 334 334 334 ARG ARG A . n 
A 1 335 THR 335 335 335 THR THR A . n 
A 1 336 ASN 336 336 336 ASN ASN A . n 
A 1 337 PHE 337 337 337 PHE PHE A . n 
A 1 338 ARG 338 338 338 ARG ARG A . n 
A 1 339 MET 339 339 339 MET MET A . n 
A 1 340 ASP 340 340 340 ASP ASP A . n 
A 1 341 PHE 341 341 341 PHE PHE A . n 
A 1 342 PRO 342 342 342 PRO PRO A . n 
A 1 343 PHE 343 343 343 PHE PHE A . n 
A 1 344 ASP 344 344 344 ASP ASP A . n 
A 1 345 LEU 345 345 345 LEU LEU A . n 
A 1 346 LYS 346 346 346 LYS LYS A . n 
A 1 347 GLU 347 347 347 GLU GLU A . n 
A 1 348 LEU 348 348 348 LEU LEU A . n 
A 1 349 PRO 349 349 349 PRO PRO A . n 
A 1 350 ALA 350 350 350 ALA ALA A . n 
A 1 351 PHE 351 351 351 PHE PHE A . n 
A 1 352 ALA 352 352 352 ALA ALA A . n 
A 1 353 ALA 353 353 353 ALA ALA A . n 
A 1 354 ILE 354 354 354 ILE ILE A . n 
A 1 355 GLY 355 355 355 GLY GLY A . n 
A 1 356 ILE 356 356 356 ILE ILE A . n 
A 1 357 CYS 357 357 357 CYS CYS A . n 
A 1 358 CYS 358 358 358 CYS CYS A . n 
A 1 359 GLY 359 359 359 GLY GLY A . n 
A 1 360 LEU 360 360 360 LEU LEU A . n 
A 1 361 LEU 361 361 361 LEU LEU A . n 
A 1 362 GLY 362 362 362 GLY GLY A . n 
A 1 363 ALA 363 363 363 ALA ALA A . n 
A 1 364 VAL 364 364 364 VAL VAL A . n 
A 1 365 PHE 365 365 365 PHE PHE A . n 
A 1 366 VAL 366 366 366 VAL VAL A . n 
A 1 367 TYR 367 367 367 TYR TYR A . n 
A 1 368 LEU 368 368 368 LEU LEU A . n 
A 1 369 HIS 369 369 369 HIS HIS A . n 
A 1 370 ARG 370 370 370 ARG ARG A . n 
A 1 371 GLN 371 371 371 GLN GLN A . n 
A 1 372 VAL 372 372 372 VAL VAL A . n 
A 1 373 MET 373 373 373 MET MET A . n 
A 1 374 LEU 374 374 374 LEU LEU A . n 
A 1 375 GLY 375 375 375 GLY GLY A . n 
A 1 376 VAL 376 376 376 VAL VAL A . n 
A 1 377 ARG 377 377 377 ARG ARG A . n 
A 1 378 LYS 378 378 378 LYS LYS A . n 
A 1 379 HIS 379 379 379 HIS HIS A . n 
A 1 380 LYS 380 380 380 LYS LYS A . n 
A 1 381 ALA 381 381 381 ALA ALA A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 SER 383 383 383 SER SER A . n 
A 1 384 GLN 384 384 384 GLN GLN A . n 
A 1 385 PHE 385 385 385 PHE PHE A . n 
A 1 386 LEU 386 386 386 LEU LEU A . n 
A 1 387 ALA 387 387 387 ALA ALA A . n 
A 1 388 LYS 388 388 388 LYS LYS A . n 
A 1 389 HIS 389 389 389 HIS HIS A . n 
A 1 390 ARG 390 390 390 ARG ARG A . n 
A 1 391 LEU 391 391 391 LEU LEU A . n 
A 1 392 LEU 392 392 392 LEU LEU A . n 
A 1 393 TYR 393 393 393 TYR TYR A . n 
A 1 394 PRO 394 394 394 PRO PRO A . n 
A 1 395 GLY 395 395 395 GLY GLY A . n 
A 1 396 ILE 396 396 396 ILE ILE A . n 
A 1 397 VAL 397 397 397 VAL VAL A . n 
A 1 398 THR 398 398 398 THR THR A . n 
A 1 399 PHE 399 399 399 PHE PHE A . n 
A 1 400 VAL 400 400 400 VAL VAL A . n 
A 1 401 ILE 401 401 401 ILE ILE A . n 
A 1 402 ALA 402 402 402 ALA ALA A . n 
A 1 403 SER 403 403 403 SER SER A . n 
A 1 404 PHE 404 404 404 PHE PHE A . n 
A 1 405 THR 405 405 405 THR THR A . n 
A 1 406 PHE 406 406 406 PHE PHE A . n 
A 1 407 PRO 407 407 407 PRO PRO A . n 
A 1 408 PRO 408 408 408 PRO PRO A . n 
A 1 409 GLY 409 409 409 GLY GLY A . n 
A 1 410 MET 410 410 410 MET MET A . n 
A 1 411 GLY 411 411 411 GLY GLY A . n 
A 1 412 GLN 412 412 412 GLN GLN A . n 
A 1 413 PHE 413 413 413 PHE PHE A . n 
A 1 414 MET 414 414 414 MET MET A . n 
A 1 415 ALA 415 415 415 ALA ALA A . n 
A 1 416 GLY 416 416 416 GLY GLY A . n 
A 1 417 GLU 417 417 417 GLU GLU A . n 
A 1 418 LEU 418 418 418 LEU LEU A . n 
A 1 419 MET 419 419 419 MET MET A . n 
A 1 420 PRO 420 420 420 PRO PRO A . n 
A 1 421 ARG 421 421 421 ARG ARG A . n 
A 1 422 GLU 422 422 422 GLU GLU A . n 
A 1 423 ALA 423 423 423 ALA ALA A . n 
A 1 424 ILE 424 424 424 ILE ILE A . n 
A 1 425 SER 425 425 425 SER SER A . n 
A 1 426 THR 426 426 426 THR THR A . n 
A 1 427 LEU 427 427 427 LEU LEU A . n 
A 1 428 PHE 428 428 428 PHE PHE A . n 
A 1 429 ASP 429 429 429 ASP ASP A . n 
A 1 430 ASN 430 430 430 ASN ASN A . n 
A 1 431 ASN 431 431 431 ASN ASN A . n 
A 1 432 THR 432 432 432 THR THR A . n 
A 1 433 TRP 433 433 433 TRP TRP A . n 
A 1 434 VAL 434 434 434 VAL VAL A . n 
A 1 435 LYS 435 435 435 LYS LYS A . n 
A 1 436 HIS 436 436 436 HIS HIS A . n 
A 1 437 ALA 437 437 437 ALA ALA A . n 
A 1 438 GLY 438 438 438 GLY GLY A . n 
A 1 439 ASP 439 439 439 ASP ASP A . n 
A 1 440 PRO 440 440 440 PRO PRO A . n 
A 1 441 GLU 441 441 441 GLU GLU A . n 
A 1 442 SER 442 442 442 SER SER A . n 
A 1 443 LEU 443 443 443 LEU LEU A . n 
A 1 444 GLY 444 444 444 GLY GLY A . n 
A 1 445 GLN 445 445 445 GLN GLN A . n 
A 1 446 SER 446 446 446 SER SER A . n 
A 1 447 ALA 447 447 447 ALA ALA A . n 
A 1 448 VAL 448 448 448 VAL VAL A . n 
A 1 449 TRP 449 449 449 TRP TRP A . n 
A 1 450 ILE 450 450 450 ILE ILE A . n 
A 1 451 HIS 451 451 451 HIS HIS A . n 
A 1 452 PRO 452 452 452 PRO PRO A . n 
A 1 453 ARG 453 453 453 ARG ARG A . n 
A 1 454 VAL 454 454 454 VAL VAL A . n 
A 1 455 ASN 455 455 455 ASN ASN A . n 
A 1 456 VAL 456 456 456 VAL VAL A . n 
A 1 457 VAL 457 457 457 VAL VAL A . n 
A 1 458 ILE 458 458 458 ILE ILE A . n 
A 1 459 ILE 459 459 459 ILE ILE A . n 
A 1 460 ILE 460 460 460 ILE ILE A . n 
A 1 461 PHE 461 461 461 PHE PHE A . n 
A 1 462 LEU 462 462 462 LEU LEU A . n 
A 1 463 PHE 463 463 463 PHE PHE A . n 
A 1 464 PHE 464 464 464 PHE PHE A . n 
A 1 465 VAL 465 465 465 VAL VAL A . n 
A 1 466 MET 466 466 466 MET MET A . n 
A 1 467 LYS 467 467 467 LYS LYS A . n 
A 1 468 PHE 468 468 468 PHE PHE A . n 
A 1 469 TRP 469 469 469 TRP TRP A . n 
A 1 470 MET 470 470 470 MET MET A . n 
A 1 471 SER 471 471 471 SER SER A . n 
A 1 472 ILE 472 472 472 ILE ILE A . n 
A 1 473 VAL 473 473 473 VAL VAL A . n 
A 1 474 ALA 474 474 474 ALA ALA A . n 
A 1 475 THR 475 475 475 THR THR A . n 
A 1 476 THR 476 476 476 THR THR A . n 
A 1 477 MET 477 477 477 MET MET A . n 
A 1 478 PRO 478 478 478 PRO PRO A . n 
A 1 479 ILE 479 479 479 ILE ILE A . n 
A 1 480 PRO 480 480 480 PRO PRO A . n 
A 1 481 CYS 481 481 481 CYS CYS A . n 
A 1 482 GLY 482 482 482 GLY GLY A . n 
A 1 483 GLY 483 483 483 GLY GLY A . n 
A 1 484 PHE 484 484 484 PHE PHE A . n 
A 1 485 MET 485 485 485 MET MET A . n 
A 1 486 PRO 486 486 486 PRO PRO A . n 
A 1 487 VAL 487 487 487 VAL VAL A . n 
A 1 488 PHE 488 488 488 PHE PHE A . n 
A 1 489 VAL 489 489 489 VAL VAL A . n 
A 1 490 LEU 490 490 490 LEU LEU A . n 
A 1 491 GLY 491 491 491 GLY GLY A . n 
A 1 492 ALA 492 492 492 ALA ALA A . n 
A 1 493 ALA 493 493 493 ALA ALA A . n 
A 1 494 PHE 494 494 494 PHE PHE A . n 
A 1 495 GLY 495 495 495 GLY GLY A . n 
A 1 496 ARG 496 496 496 ARG ARG A . n 
A 1 497 LEU 497 497 497 LEU LEU A . n 
A 1 498 VAL 498 498 498 VAL VAL A . n 
A 1 499 GLY 499 499 499 GLY GLY A . n 
A 1 500 GLU 500 500 500 GLU GLU A . n 
A 1 501 ILE 501 501 501 ILE ILE A . n 
A 1 502 MET 502 502 502 MET MET A . n 
A 1 503 ALA 503 503 503 ALA ALA A . n 
A 1 504 MET 504 504 504 MET MET A . n 
A 1 505 LEU 505 505 505 LEU LEU A . n 
A 1 506 PHE 506 506 506 PHE PHE A . n 
A 1 507 PRO 507 507 507 PRO PRO A . n 
A 1 508 ASP 508 508 508 ASP ASP A . n 
A 1 509 GLY 509 509 509 GLY GLY A . n 
A 1 510 ILE 510 510 510 ILE ILE A . n 
A 1 511 LEU 511 511 511 LEU LEU A . n 
A 1 512 PHE 512 512 512 PHE PHE A . n 
A 1 513 ASP 513 513 513 ASP ASP A . n 
A 1 514 ASP 514 514 514 ASP ASP A . n 
A 1 515 ILE 515 515 515 ILE ILE A . n 
A 1 516 ILE 516 516 516 ILE ILE A . n 
A 1 517 TYR 517 517 517 TYR TYR A . n 
A 1 518 LYS 518 518 518 LYS LYS A . n 
A 1 519 ILE 519 519 519 ILE ILE A . n 
A 1 520 LEU 520 520 520 LEU LEU A . n 
A 1 521 PRO 521 521 521 PRO PRO A . n 
A 1 522 GLY 522 522 522 GLY GLY A . n 
A 1 523 GLY 523 523 523 GLY GLY A . n 
A 1 524 TYR 524 524 524 TYR TYR A . n 
A 1 525 ALA 525 525 525 ALA ALA A . n 
A 1 526 VAL 526 526 526 VAL VAL A . n 
A 1 527 ILE 527 527 527 ILE ILE A . n 
A 1 528 GLY 528 528 528 GLY GLY A . n 
A 1 529 ALA 529 529 529 ALA ALA A . n 
A 1 530 ALA 530 530 530 ALA ALA A . n 
A 1 531 ALA 531 531 531 ALA ALA A . n 
A 1 532 LEU 532 532 532 LEU LEU A . n 
A 1 533 THR 533 533 533 THR THR A . n 
A 1 534 GLY 534 534 534 GLY GLY A . n 
A 1 535 ALA 535 535 535 ALA ALA A . n 
A 1 536 VAL 536 536 536 VAL VAL A . n 
A 1 537 SER 537 537 537 SER SER A . n 
A 1 538 HIS 538 538 538 HIS HIS A . n 
A 1 539 THR 539 539 539 THR THR A . n 
A 1 540 VAL 540 540 540 VAL VAL A . n 
A 1 541 SER 541 541 541 SER SER A . n 
A 1 542 THR 542 542 542 THR THR A . n 
A 1 543 ALA 543 543 543 ALA ALA A . n 
A 1 544 VAL 544 544 544 VAL VAL A . n 
A 1 545 ILE 545 545 545 ILE ILE A . n 
A 1 546 CYS 546 546 546 CYS CYS A . n 
A 1 547 PHE 547 547 547 PHE PHE A . n 
A 1 548 GLU 548 548 548 GLU GLU A . n 
A 1 549 LEU 549 549 549 LEU LEU A . n 
A 1 550 THR 550 550 550 THR THR A . n 
A 1 551 GLY 551 551 551 GLY GLY A . n 
A 1 552 GLN 552 552 552 GLN GLN A . n 
A 1 553 ILE 553 553 553 ILE ILE A . n 
A 1 554 ALA 554 554 554 ALA ALA A . n 
A 1 555 HIS 555 555 555 HIS HIS A . n 
A 1 556 ILE 556 556 556 ILE ILE A . n 
A 1 557 LEU 557 557 557 LEU LEU A . n 
A 1 558 PRO 558 558 558 PRO PRO A . n 
A 1 559 MET 559 559 559 MET MET A . n 
A 1 560 MET 560 560 560 MET MET A . n 
A 1 561 VAL 561 561 561 VAL VAL A . n 
A 1 562 ALA 562 562 562 ALA ALA A . n 
A 1 563 VAL 563 563 563 VAL VAL A . n 
A 1 564 ILE 564 564 564 ILE ILE A . n 
A 1 565 LEU 565 565 565 LEU LEU A . n 
A 1 566 ALA 566 566 566 ALA ALA A . n 
A 1 567 ASN 567 567 567 ASN ASN A . n 
A 1 568 MET 568 568 568 MET MET A . n 
A 1 569 VAL 569 569 569 VAL VAL A . n 
A 1 570 ALA 570 570 570 ALA ALA A . n 
A 1 571 GLN 571 571 571 GLN GLN A . n 
A 1 572 SER 572 572 572 SER SER A . n 
A 1 573 LEU 573 573 573 LEU LEU A . n 
A 1 574 GLN 574 574 574 GLN GLN A . n 
A 1 575 PRO 575 575 575 PRO PRO A . n 
A 1 576 SER 576 576 576 SER SER A . n 
A 1 577 LEU 577 577 577 LEU LEU A . n 
A 1 578 TYR 578 578 578 TYR TYR A . n 
A 1 579 ASP 579 579 579 ASP ASP A . n 
A 1 580 SER 580 580 580 SER SER A . n 
A 1 581 ILE 581 581 581 ILE ILE A . n 
A 1 582 ILE 582 582 582 ILE ILE A . n 
A 1 583 GLN 583 583 583 GLN GLN A . n 
A 1 584 VAL 584 584 584 VAL VAL A . n 
A 1 585 LYS 585 585 585 LYS LYS A . n 
A 1 586 LYS 586 586 586 LYS LYS A . n 
A 1 587 LEU 587 587 587 LEU LEU A . n 
A 1 588 PRO 588 588 588 PRO PRO A . n 
A 1 589 TYR 589 589 589 TYR TYR A . n 
A 1 590 LEU 590 590 ?   ?   ?   A . n 
A 1 591 PRO 591 591 ?   ?   ?   A . n 
A 1 592 ASP 592 592 ?   ?   ?   A . n 
A 1 593 LEU 593 593 ?   ?   ?   A . n 
A 1 594 GLY 594 594 ?   ?   ?   A . n 
A 1 595 TRP 595 595 ?   ?   ?   A . n 
A 1 596 ASN 596 596 ?   ?   ?   A . n 
A 1 597 GLN 597 597 ?   ?   ?   A . n 
A 1 598 LEU 598 598 ?   ?   ?   A . n 
A 1 599 SER 599 599 ?   ?   ?   A . n 
A 1 600 LYS 600 600 ?   ?   ?   A . n 
A 1 601 TYR 601 601 ?   ?   ?   A . n 
A 1 602 THR 602 602 ?   ?   ?   A . n 
A 1 603 ILE 603 603 ?   ?   ?   A . n 
A 1 604 PHE 604 604 ?   ?   ?   A . n 
A 1 605 VAL 605 605 ?   ?   ?   A . n 
A 1 606 GLU 606 606 ?   ?   ?   A . n 
A 1 607 ASP 607 607 ?   ?   ?   A . n 
A 1 608 ILE 608 608 ?   ?   ?   A . n 
A 1 609 MET 609 609 ?   ?   ?   A . n 
A 1 610 VAL 610 610 ?   ?   ?   A . n 
A 1 611 ARG 611 611 ?   ?   ?   A . n 
A 1 612 ASP 612 612 ?   ?   ?   A . n 
A 1 613 VAL 613 613 ?   ?   ?   A . n 
A 1 614 LYS 614 614 ?   ?   ?   A . n 
A 1 615 PHE 615 615 ?   ?   ?   A . n 
A 1 616 VAL 616 616 ?   ?   ?   A . n 
A 1 617 SER 617 617 ?   ?   ?   A . n 
A 1 618 ALA 618 618 ?   ?   ?   A . n 
A 1 619 SER 619 619 ?   ?   ?   A . n 
A 1 620 TYR 620 620 ?   ?   ?   A . n 
A 1 621 THR 621 621 ?   ?   ?   A . n 
A 1 622 TYR 622 622 ?   ?   ?   A . n 
A 1 623 GLY 623 623 ?   ?   ?   A . n 
A 1 624 GLU 624 624 ?   ?   ?   A . n 
A 1 625 LEU 625 625 ?   ?   ?   A . n 
A 1 626 ARG 626 626 ?   ?   ?   A . n 
A 1 627 THR 627 627 ?   ?   ?   A . n 
A 1 628 LEU 628 628 ?   ?   ?   A . n 
A 1 629 LEU 629 629 ?   ?   ?   A . n 
A 1 630 GLN 630 630 ?   ?   ?   A . n 
A 1 631 THR 631 631 ?   ?   ?   A . n 
A 1 632 THR 632 632 ?   ?   ?   A . n 
A 1 633 THR 633 633 ?   ?   ?   A . n 
A 1 634 VAL 634 634 ?   ?   ?   A . n 
A 1 635 LYS 635 635 ?   ?   ?   A . n 
A 1 636 THR 636 636 ?   ?   ?   A . n 
A 1 637 LEU 637 637 ?   ?   ?   A . n 
A 1 638 PRO 638 638 ?   ?   ?   A . n 
A 1 639 LEU 639 639 ?   ?   ?   A . n 
A 1 640 VAL 640 640 ?   ?   ?   A . n 
A 1 641 ASP 641 641 ?   ?   ?   A . n 
A 1 642 SER 642 642 ?   ?   ?   A . n 
A 1 643 LYS 643 643 ?   ?   ?   A . n 
A 1 644 ASP 644 644 ?   ?   ?   A . n 
A 1 645 SER 645 645 ?   ?   ?   A . n 
A 1 646 MET 646 646 ?   ?   ?   A . n 
A 1 647 ILE 647 647 ?   ?   ?   A . n 
A 1 648 LEU 648 648 ?   ?   ?   A . n 
A 1 649 LEU 649 649 ?   ?   ?   A . n 
A 1 650 GLY 650 650 ?   ?   ?   A . n 
A 1 651 SER 651 651 ?   ?   ?   A . n 
A 1 652 VAL 652 652 ?   ?   ?   A . n 
A 1 653 GLU 653 653 ?   ?   ?   A . n 
A 1 654 ARG 654 654 ?   ?   ?   A . n 
A 1 655 SER 655 655 ?   ?   ?   A . n 
A 1 656 GLU 656 656 ?   ?   ?   A . n 
A 1 657 LEU 657 657 ?   ?   ?   A . n 
A 1 658 GLN 658 658 ?   ?   ?   A . n 
A 1 659 ALA 659 659 ?   ?   ?   A . n 
A 1 660 LEU 660 660 ?   ?   ?   A . n 
A 1 661 LEU 661 661 ?   ?   ?   A . n 
A 1 662 GLN 662 662 ?   ?   ?   A . n 
A 1 663 ARG 663 663 ?   ?   ?   A . n 
A 1 664 HIS 664 664 ?   ?   ?   A . n 
A 1 665 LEU 665 665 ?   ?   ?   A . n 
A 1 666 CYS 666 666 ?   ?   ?   A . n 
A 1 667 PRO 667 667 ?   ?   ?   A . n 
A 1 668 GLU 668 668 ?   ?   ?   A . n 
A 1 669 ARG 669 669 ?   ?   ?   A . n 
A 1 670 ARG 670 670 ?   ?   ?   A . n 
A 1 671 LEU 671 671 ?   ?   ?   A . n 
A 1 672 ARG 672 672 ?   ?   ?   A . n 
A 1 673 ALA 673 673 ?   ?   ?   A . n 
A 1 674 ALA 674 674 ?   ?   ?   A . n 
A 1 675 GLN 675 675 ?   ?   ?   A . n 
A 1 676 GLU 676 676 ?   ?   ?   A . n 
A 1 677 MET 677 677 ?   ?   ?   A . n 
A 1 678 ALA 678 678 ?   ?   ?   A . n 
A 1 679 ARG 679 679 ?   ?   ?   A . n 
A 1 680 LYS 680 680 ?   ?   ?   A . n 
A 1 681 LEU 681 681 ?   ?   ?   A . n 
A 1 682 SER 682 682 ?   ?   ?   A . n 
A 1 683 GLU 683 683 ?   ?   ?   A . n 
A 1 684 LEU 684 684 ?   ?   ?   A . n 
A 1 685 PRO 685 685 ?   ?   ?   A . n 
A 1 686 TYR 686 686 ?   ?   ?   A . n 
A 1 687 ASP 687 687 ?   ?   ?   A . n 
A 1 688 GLY 688 688 ?   ?   ?   A . n 
A 1 689 LYS 689 689 ?   ?   ?   A . n 
A 1 690 ALA 690 690 ?   ?   ?   A . n 
A 1 691 ARG 691 691 ?   ?   ?   A . n 
A 1 692 LEU 692 692 ?   ?   ?   A . n 
A 1 693 ALA 693 693 ?   ?   ?   A . n 
A 1 694 GLY 694 694 ?   ?   ?   A . n 
A 1 695 GLU 695 695 ?   ?   ?   A . n 
A 1 696 GLY 696 696 ?   ?   ?   A . n 
A 1 697 LEU 697 697 ?   ?   ?   A . n 
A 1 698 PRO 698 698 ?   ?   ?   A . n 
A 1 699 GLY 699 699 ?   ?   ?   A . n 
A 1 700 ALA 700 700 ?   ?   ?   A . n 
A 1 701 PRO 701 701 ?   ?   ?   A . n 
A 1 702 PRO 702 702 ?   ?   ?   A . n 
A 1 703 GLY 703 703 ?   ?   ?   A . n 
A 1 704 ARG 704 704 ?   ?   ?   A . n 
A 1 705 PRO 705 705 ?   ?   ?   A . n 
A 1 706 GLU 706 706 ?   ?   ?   A . n 
A 1 707 SER 707 707 ?   ?   ?   A . n 
A 1 708 PHE 708 708 ?   ?   ?   A . n 
A 1 709 ALA 709 709 ?   ?   ?   A . n 
A 1 710 PHE 710 710 ?   ?   ?   A . n 
A 1 711 VAL 711 711 ?   ?   ?   A . n 
A 1 712 ASP 712 712 ?   ?   ?   A . n 
A 1 713 GLU 713 713 ?   ?   ?   A . n 
A 1 714 ASP 714 714 ?   ?   ?   A . n 
A 1 715 GLU 715 715 ?   ?   ?   A . n 
A 1 716 ASP 716 716 ?   ?   ?   A . n 
A 1 717 GLU 717 717 ?   ?   ?   A . n 
A 1 718 ASP 718 718 ?   ?   ?   A . n 
A 1 719 LEU 719 719 ?   ?   ?   A . n 
A 1 720 SER 720 720 ?   ?   ?   A . n 
A 1 721 GLY 721 721 ?   ?   ?   A . n 
A 1 722 LYS 722 722 ?   ?   ?   A . n 
A 1 723 SER 723 723 ?   ?   ?   A . n 
A 1 724 GLU 724 724 ?   ?   ?   A . n 
A 1 725 LEU 725 725 ?   ?   ?   A . n 
A 1 726 PRO 726 726 ?   ?   ?   A . n 
A 1 727 PRO 727 727 ?   ?   ?   A . n 
A 1 728 SER 728 728 ?   ?   ?   A . n 
A 1 729 LEU 729 729 ?   ?   ?   A . n 
A 1 730 ALA 730 730 ?   ?   ?   A . n 
A 1 731 LEU 731 731 ?   ?   ?   A . n 
A 1 732 HIS 732 732 ?   ?   ?   A . n 
A 1 733 PRO 733 733 ?   ?   ?   A . n 
A 1 734 SER 734 734 ?   ?   ?   A . n 
A 1 735 THR 735 735 ?   ?   ?   A . n 
A 1 736 THR 736 736 ?   ?   ?   A . n 
A 1 737 ALA 737 737 ?   ?   ?   A . n 
A 1 738 PRO 738 738 ?   ?   ?   A . n 
A 1 739 LEU 739 739 ?   ?   ?   A . n 
A 1 740 SER 740 740 ?   ?   ?   A . n 
A 1 741 PRO 741 741 ?   ?   ?   A . n 
A 1 742 GLU 742 742 ?   ?   ?   A . n 
A 1 743 GLU 743 743 ?   ?   ?   A . n 
A 1 744 PRO 744 744 ?   ?   ?   A . n 
A 1 745 ASN 745 745 ?   ?   ?   A . n 
A 1 746 GLY 746 746 ?   ?   ?   A . n 
A 1 747 PRO 747 747 ?   ?   ?   A . n 
A 1 748 LEU 748 748 ?   ?   ?   A . n 
A 1 749 PRO 749 749 ?   ?   ?   A . n 
A 1 750 GLY 750 750 ?   ?   ?   A . n 
A 1 751 HIS 751 751 ?   ?   ?   A . n 
A 1 752 LYS 752 752 ?   ?   ?   A . n 
A 1 753 GLN 753 753 ?   ?   ?   A . n 
A 1 754 GLN 754 754 ?   ?   ?   A . n 
A 1 755 PRO 755 755 ?   ?   ?   A . n 
A 1 756 GLU 756 756 ?   ?   ?   A . n 
A 1 757 ALA 757 757 ?   ?   ?   A . n 
A 1 758 PRO 758 758 ?   ?   ?   A . n 
A 1 759 GLU 759 759 ?   ?   ?   A . n 
A 1 760 PRO 760 760 ?   ?   ?   A . n 
A 1 761 ALA 761 761 ?   ?   ?   A . n 
A 1 762 GLY 762 762 ?   ?   ?   A . n 
A 1 763 GLN 763 763 ?   ?   ?   A . n 
A 1 764 ARG 764 764 ?   ?   ?   A . n 
A 1 765 PRO 765 765 ?   ?   ?   A . n 
A 1 766 SER 766 766 ?   ?   ?   A . n 
A 1 767 ILE 767 767 ?   ?   ?   A . n 
A 1 768 PHE 768 768 ?   ?   ?   A . n 
A 1 769 GLN 769 769 ?   ?   ?   A . n 
A 1 770 SER 770 770 ?   ?   ?   A . n 
A 1 771 LEU 771 771 ?   ?   ?   A . n 
A 1 772 LEU 772 772 ?   ?   ?   A . n 
A 1 773 HIS 773 773 ?   ?   ?   A . n 
A 1 774 CYS 774 774 ?   ?   ?   A . n 
A 1 775 LEU 775 775 ?   ?   ?   A . n 
A 1 776 LEU 776 776 ?   ?   ?   A . n 
A 1 777 GLY 777 777 ?   ?   ?   A . n 
A 1 778 ARG 778 778 ?   ?   ?   A . n 
A 1 779 ALA 779 779 ?   ?   ?   A . n 
A 1 780 ARG 780 780 ?   ?   ?   A . n 
A 1 781 PRO 781 781 ?   ?   ?   A . n 
A 1 782 THR 782 782 ?   ?   ?   A . n 
A 1 783 LYS 783 783 ?   ?   ?   A . n 
A 1 784 LYS 784 784 ?   ?   ?   A . n 
A 1 785 LYS 785 785 ?   ?   ?   A . n 
A 1 786 THR 786 786 ?   ?   ?   A . n 
A 1 787 THR 787 787 ?   ?   ?   A . n 
A 1 788 GLN 788 788 ?   ?   ?   A . n 
A 1 789 ASP 789 789 ?   ?   ?   A . n 
A 1 790 SER 790 790 ?   ?   ?   A . n 
A 1 791 THR 791 791 ?   ?   ?   A . n 
A 1 792 ASP 792 792 ?   ?   ?   A . n 
A 1 793 LEU 793 793 ?   ?   ?   A . n 
A 1 794 VAL 794 794 ?   ?   ?   A . n 
A 1 795 ASP 795 795 ?   ?   ?   A . n 
A 1 796 ASN 796 796 ?   ?   ?   A . n 
A 1 797 MET 797 797 ?   ?   ?   A . n 
A 1 798 SER 798 798 ?   ?   ?   A . n 
A 1 799 PRO 799 799 ?   ?   ?   A . n 
A 1 800 GLU 800 800 ?   ?   ?   A . n 
A 1 801 GLU 801 801 ?   ?   ?   A . n 
A 1 802 ILE 802 802 ?   ?   ?   A . n 
A 1 803 GLU 803 803 ?   ?   ?   A . n 
A 1 804 ALA 804 804 ?   ?   ?   A . n 
A 1 805 TRP 805 805 ?   ?   ?   A . n 
A 1 806 GLU 806 806 ?   ?   ?   A . n 
A 1 807 GLN 807 807 ?   ?   ?   A . n 
A 1 808 GLU 808 808 ?   ?   ?   A . n 
A 1 809 GLN 809 809 ?   ?   ?   A . n 
A 1 810 LEU 810 810 ?   ?   ?   A . n 
A 1 811 SER 811 811 ?   ?   ?   A . n 
A 1 812 GLN 812 812 ?   ?   ?   A . n 
A 1 813 PRO 813 813 ?   ?   ?   A . n 
A 1 814 VAL 814 814 ?   ?   ?   A . n 
A 1 815 CYS 815 815 ?   ?   ?   A . n 
A 1 816 PHE 816 816 ?   ?   ?   A . n 
A 1 817 ASP 817 817 ?   ?   ?   A . n 
A 1 818 SER 818 818 ?   ?   ?   A . n 
A 1 819 CYS 819 819 ?   ?   ?   A . n 
A 1 820 CYS 820 820 ?   ?   ?   A . n 
A 1 821 ILE 821 821 ?   ?   ?   A . n 
A 1 822 ASP 822 822 ?   ?   ?   A . n 
A 1 823 GLN 823 823 ?   ?   ?   A . n 
A 1 824 SER 824 824 ?   ?   ?   A . n 
A 1 825 PRO 825 825 ?   ?   ?   A . n 
A 1 826 PHE 826 826 ?   ?   ?   A . n 
A 1 827 GLN 827 827 ?   ?   ?   A . n 
A 1 828 LEU 828 828 ?   ?   ?   A . n 
A 1 829 VAL 829 829 ?   ?   ?   A . n 
A 1 830 GLU 830 830 ?   ?   ?   A . n 
A 1 831 GLN 831 831 ?   ?   ?   A . n 
A 1 832 THR 832 832 ?   ?   ?   A . n 
A 1 833 THR 833 833 ?   ?   ?   A . n 
A 1 834 LEU 834 834 ?   ?   ?   A . n 
A 1 835 HIS 835 835 ?   ?   ?   A . n 
A 1 836 LYS 836 836 ?   ?   ?   A . n 
A 1 837 THR 837 837 ?   ?   ?   A . n 
A 1 838 HIS 838 838 ?   ?   ?   A . n 
A 1 839 THR 839 839 ?   ?   ?   A . n 
A 1 840 LEU 840 840 ?   ?   ?   A . n 
A 1 841 PHE 841 841 ?   ?   ?   A . n 
A 1 842 SER 842 842 ?   ?   ?   A . n 
A 1 843 LEU 843 843 ?   ?   ?   A . n 
A 1 844 LEU 844 844 ?   ?   ?   A . n 
A 1 845 GLY 845 845 ?   ?   ?   A . n 
A 1 846 LEU 846 846 ?   ?   ?   A . n 
A 1 847 HIS 847 847 ?   ?   ?   A . n 
A 1 848 LEU 848 848 ?   ?   ?   A . n 
A 1 849 ALA 849 849 ?   ?   ?   A . n 
A 1 850 TYR 850 850 ?   ?   ?   A . n 
A 1 851 VAL 851 851 ?   ?   ?   A . n 
A 1 852 THR 852 852 ?   ?   ?   A . n 
A 1 853 SER 853 853 ?   ?   ?   A . n 
A 1 854 MET 854 854 ?   ?   ?   A . n 
A 1 855 GLY 855 855 ?   ?   ?   A . n 
A 1 856 LYS 856 856 ?   ?   ?   A . n 
A 1 857 LEU 857 857 ?   ?   ?   A . n 
A 1 858 ARG 858 858 ?   ?   ?   A . n 
A 1 859 GLY 859 859 ?   ?   ?   A . n 
A 1 860 VAL 860 860 ?   ?   ?   A . n 
A 1 861 LEU 861 861 ?   ?   ?   A . n 
A 1 862 ALA 862 862 ?   ?   ?   A . n 
A 1 863 LEU 863 863 ?   ?   ?   A . n 
A 1 864 GLU 864 864 ?   ?   ?   A . n 
A 1 865 GLU 865 865 ?   ?   ?   A . n 
A 1 866 LEU 866 866 ?   ?   ?   A . n 
A 1 867 GLN 867 867 ?   ?   ?   A . n 
A 1 868 LYS 868 868 ?   ?   ?   A . n 
A 1 869 ALA 869 869 ?   ?   ?   A . n 
A 1 870 ILE 870 870 ?   ?   ?   A . n 
A 1 871 GLU 871 871 ?   ?   ?   A . n 
A 1 872 GLY 872 872 ?   ?   ?   A . n 
A 1 873 HIS 873 873 ?   ?   ?   A . n 
A 1 874 THR 874 874 ?   ?   ?   A . n 
A 1 875 LYS 875 875 ?   ?   ?   A . n 
A 1 876 SER 876 876 ?   ?   ?   A . n 
A 1 877 GLY 877 877 ?   ?   ?   A . n 
A 1 878 VAL 878 878 ?   ?   ?   A . n 
A 1 879 GLN 879 879 ?   ?   ?   A . n 
A 1 880 LEU 880 880 ?   ?   ?   A . n 
A 1 881 ARG 881 881 ?   ?   ?   A . n 
A 1 882 PRO 882 882 ?   ?   ?   A . n 
A 1 883 PRO 883 883 ?   ?   ?   A . n 
A 1 884 LEU 884 884 ?   ?   ?   A . n 
A 1 885 ALA 885 885 ?   ?   ?   A . n 
A 1 886 SER 886 886 ?   ?   ?   A . n 
A 1 887 PHE 887 887 ?   ?   ?   A . n 
A 1 888 ARG 888 888 ?   ?   ?   A . n 
A 1 889 ASN 889 889 ?   ?   ?   A . n 
A 1 890 THR 890 890 ?   ?   ?   A . n 
A 1 891 THR 891 891 ?   ?   ?   A . n 
A 1 892 SER 892 892 ?   ?   ?   A . n 
A 1 893 THR 893 893 ?   ?   ?   A . n 
A 1 894 ARG 894 894 ?   ?   ?   A . n 
A 1 895 LYS 895 895 ?   ?   ?   A . n 
A 1 896 SER 896 896 ?   ?   ?   A . n 
A 1 897 THR 897 897 ?   ?   ?   A . n 
A 1 898 GLY 898 898 ?   ?   ?   A . n 
A 1 899 ALA 899 899 ?   ?   ?   A . n 
A 1 900 PRO 900 900 ?   ?   ?   A . n 
A 1 901 PRO 901 901 ?   ?   ?   A . n 
A 1 902 SER 902 902 ?   ?   ?   A . n 
A 1 903 SER 903 903 ?   ?   ?   A . n 
A 1 904 ALA 904 904 ?   ?   ?   A . n 
A 1 905 GLU 905 905 ?   ?   ?   A . n 
A 1 906 ASN 906 906 ?   ?   ?   A . n 
A 1 907 TRP 907 907 ?   ?   ?   A . n 
A 1 908 ASN 908 908 ?   ?   ?   A . n 
A 1 909 LEU 909 909 ?   ?   ?   A . n 
A 1 910 PRO 910 910 ?   ?   ?   A . n 
A 1 911 GLU 911 911 ?   ?   ?   A . n 
A 1 912 ASP 912 912 ?   ?   ?   A . n 
A 1 913 ARG 913 913 ?   ?   ?   A . n 
A 1 914 PRO 914 914 ?   ?   ?   A . n 
A 1 915 GLY 915 915 ?   ?   ?   A . n 
A 1 916 ALA 916 916 ?   ?   ?   A . n 
A 1 917 THR 917 917 ?   ?   ?   A . n 
A 1 918 GLY 918 918 ?   ?   ?   A . n 
A 1 919 THR 919 919 ?   ?   ?   A . n 
A 1 920 GLY 920 920 ?   ?   ?   A . n 
A 1 921 ASP 921 921 ?   ?   ?   A . n 
A 1 922 VAL 922 922 ?   ?   ?   A . n 
A 1 923 ILE 923 923 ?   ?   ?   A . n 
A 1 924 ALA 924 924 ?   ?   ?   A . n 
A 1 925 ALA 925 925 ?   ?   ?   A . n 
A 1 926 SER 926 926 ?   ?   ?   A . n 
A 1 927 PRO 927 927 ?   ?   ?   A . n 
A 1 928 GLU 928 928 ?   ?   ?   A . n 
A 1 929 THR 929 929 ?   ?   ?   A . n 
A 1 930 PRO 930 930 ?   ?   ?   A . n 
A 1 931 VAL 931 931 ?   ?   ?   A . n 
A 1 932 PRO 932 932 ?   ?   ?   A . n 
A 1 933 SER 933 933 ?   ?   ?   A . n 
A 1 934 PRO 934 934 ?   ?   ?   A . n 
A 1 935 SER 935 935 ?   ?   ?   A . n 
A 1 936 PRO 936 936 ?   ?   ?   A . n 
A 1 937 GLU 937 937 ?   ?   ?   A . n 
A 1 938 PRO 938 938 ?   ?   ?   A . n 
A 1 939 PRO 939 939 ?   ?   ?   A . n 
A 1 940 LEU 940 940 ?   ?   ?   A . n 
A 1 941 SER 941 941 ?   ?   ?   A . n 
A 1 942 LEU 942 942 ?   ?   ?   A . n 
A 1 943 ALA 943 943 ?   ?   ?   A . n 
A 1 944 PRO 944 944 ?   ?   ?   A . n 
A 1 945 GLY 945 945 ?   ?   ?   A . n 
A 1 946 LYS 946 946 ?   ?   ?   A . n 
A 1 947 VAL 947 947 ?   ?   ?   A . n 
A 1 948 GLU 948 948 ?   ?   ?   A . n 
A 1 949 GLY 949 949 ?   ?   ?   A . n 
A 1 950 GLU 950 950 ?   ?   ?   A . n 
A 1 951 LEU 951 951 ?   ?   ?   A . n 
A 1 952 GLU 952 952 ?   ?   ?   A . n 
A 1 953 GLU 953 953 ?   ?   ?   A . n 
A 1 954 LEU 954 954 ?   ?   ?   A . n 
A 1 955 GLU 955 955 ?   ?   ?   A . n 
A 1 956 LEU 956 956 ?   ?   ?   A . n 
A 1 957 VAL 957 957 ?   ?   ?   A . n 
A 1 958 GLU 958 958 ?   ?   ?   A . n 
A 1 959 SER 959 959 ?   ?   ?   A . n 
A 1 960 PRO 960 960 ?   ?   ?   A . n 
A 1 961 GLY 961 961 ?   ?   ?   A . n 
A 1 962 LEU 962 962 ?   ?   ?   A . n 
A 1 963 GLU 963 963 ?   ?   ?   A . n 
A 1 964 GLU 964 964 ?   ?   ?   A . n 
A 1 965 GLU 965 965 ?   ?   ?   A . n 
A 1 966 LEU 966 966 ?   ?   ?   A . n 
A 1 967 ALA 967 967 ?   ?   ?   A . n 
A 1 968 ASP 968 968 ?   ?   ?   A . n 
A 1 969 ILE 969 969 ?   ?   ?   A . n 
A 1 970 LEU 970 970 ?   ?   ?   A . n 
A 1 971 GLN 971 971 ?   ?   ?   A . n 
A 1 972 GLY 972 972 ?   ?   ?   A . n 
A 1 973 PRO 973 973 ?   ?   ?   A . n 
A 1 974 SER 974 974 ?   ?   ?   A . n 
A 1 975 LEU 975 975 ?   ?   ?   A . n 
A 1 976 ARG 976 976 ?   ?   ?   A . n 
A 1 977 SER 977 977 ?   ?   ?   A . n 
A 1 978 THR 978 978 ?   ?   ?   A . n 
A 1 979 ASP 979 979 ?   ?   ?   A . n 
A 1 980 GLU 980 980 ?   ?   ?   A . n 
A 1 981 GLU 981 981 ?   ?   ?   A . n 
A 1 982 ASP 982 982 ?   ?   ?   A . n 
A 1 983 GLU 983 983 ?   ?   ?   A . n 
A 1 984 ASP 984 984 ?   ?   ?   A . n 
A 1 985 GLU 985 985 ?   ?   ?   A . n 
A 1 986 LEU 986 986 ?   ?   ?   A . n 
A 1 987 ILE 987 987 ?   ?   ?   A . n 
A 1 988 LEU 988 988 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   GLU 2   2   ?   ?   ?   B . n 
B 1 3   GLN 3   3   ?   ?   ?   B . n 
B 1 4   SER 4   4   ?   ?   ?   B . n 
B 1 5   ARG 5   5   ?   ?   ?   B . n 
B 1 6   SER 6   6   ?   ?   ?   B . n 
B 1 7   GLN 7   7   ?   ?   ?   B . n 
B 1 8   GLN 8   8   ?   ?   ?   B . n 
B 1 9   ARG 9   9   ?   ?   ?   B . n 
B 1 10  GLY 10  10  ?   ?   ?   B . n 
B 1 11  GLY 11  11  ?   ?   ?   B . n 
B 1 12  GLU 12  12  ?   ?   ?   B . n 
B 1 13  GLN 13  13  ?   ?   ?   B . n 
B 1 14  SER 14  14  ?   ?   ?   B . n 
B 1 15  TRP 15  15  ?   ?   ?   B . n 
B 1 16  TRP 16  16  ?   ?   ?   B . n 
B 1 17  GLY 17  17  ?   ?   ?   B . n 
B 1 18  SER 18  18  ?   ?   ?   B . n 
B 1 19  ASP 19  19  ?   ?   ?   B . n 
B 1 20  PRO 20  20  ?   ?   ?   B . n 
B 1 21  GLN 21  21  ?   ?   ?   B . n 
B 1 22  TYR 22  22  ?   ?   ?   B . n 
B 1 23  GLN 23  23  ?   ?   ?   B . n 
B 1 24  TYR 24  24  ?   ?   ?   B . n 
B 1 25  MET 25  25  ?   ?   ?   B . n 
B 1 26  PRO 26  26  ?   ?   ?   B . n 
B 1 27  PHE 27  27  ?   ?   ?   B . n 
B 1 28  GLU 28  28  ?   ?   ?   B . n 
B 1 29  HIS 29  29  ?   ?   ?   B . n 
B 1 30  CYS 30  30  ?   ?   ?   B . n 
B 1 31  THR 31  31  ?   ?   ?   B . n 
B 1 32  SER 32  32  ?   ?   ?   B . n 
B 1 33  TYR 33  33  ?   ?   ?   B . n 
B 1 34  GLY 34  34  ?   ?   ?   B . n 
B 1 35  LEU 35  35  ?   ?   ?   B . n 
B 1 36  PRO 36  36  ?   ?   ?   B . n 
B 1 37  SER 37  37  ?   ?   ?   B . n 
B 1 38  GLU 38  38  ?   ?   ?   B . n 
B 1 39  ASN 39  39  ?   ?   ?   B . n 
B 1 40  GLY 40  40  ?   ?   ?   B . n 
B 1 41  GLY 41  41  ?   ?   ?   B . n 
B 1 42  LEU 42  42  ?   ?   ?   B . n 
B 1 43  GLN 43  43  ?   ?   ?   B . n 
B 1 44  HIS 44  44  ?   ?   ?   B . n 
B 1 45  ARG 45  45  ?   ?   ?   B . n 
B 1 46  LEU 46  46  ?   ?   ?   B . n 
B 1 47  ARG 47  47  ?   ?   ?   B . n 
B 1 48  LYS 48  48  ?   ?   ?   B . n 
B 1 49  ASP 49  49  ?   ?   ?   B . n 
B 1 50  ALA 50  50  ?   ?   ?   B . n 
B 1 51  GLY 51  51  ?   ?   ?   B . n 
B 1 52  PRO 52  52  ?   ?   ?   B . n 
B 1 53  ARG 53  53  ?   ?   ?   B . n 
B 1 54  HIS 54  54  ?   ?   ?   B . n 
B 1 55  ASN 55  55  ?   ?   ?   B . n 
B 1 56  VAL 56  56  ?   ?   ?   B . n 
B 1 57  HIS 57  57  ?   ?   ?   B . n 
B 1 58  PRO 58  58  ?   ?   ?   B . n 
B 1 59  THR 59  59  ?   ?   ?   B . n 
B 1 60  GLN 60  60  ?   ?   ?   B . n 
B 1 61  ILE 61  61  ?   ?   ?   B . n 
B 1 62  TYR 62  62  ?   ?   ?   B . n 
B 1 63  GLY 63  63  ?   ?   ?   B . n 
B 1 64  HIS 64  64  ?   ?   ?   B . n 
B 1 65  HIS 65  65  ?   ?   ?   B . n 
B 1 66  LYS 66  66  ?   ?   ?   B . n 
B 1 67  GLU 67  67  ?   ?   ?   B . n 
B 1 68  GLN 68  68  ?   ?   ?   B . n 
B 1 69  PHE 69  69  ?   ?   ?   B . n 
B 1 70  SER 70  70  ?   ?   ?   B . n 
B 1 71  ASP 71  71  ?   ?   ?   B . n 
B 1 72  ARG 72  72  ?   ?   ?   B . n 
B 1 73  GLU 73  73  ?   ?   ?   B . n 
B 1 74  GLN 74  74  ?   ?   ?   B . n 
B 1 75  ASP 75  75  ?   ?   ?   B . n 
B 1 76  ILE 76  76  ?   ?   ?   B . n 
B 1 77  GLY 77  77  ?   ?   ?   B . n 
B 1 78  MET 78  78  ?   ?   ?   B . n 
B 1 79  PRO 79  79  ?   ?   ?   B . n 
B 1 80  LYS 80  80  ?   ?   ?   B . n 
B 1 81  LYS 81  81  ?   ?   ?   B . n 
B 1 82  THR 82  82  ?   ?   ?   B . n 
B 1 83  GLY 83  83  ?   ?   ?   B . n 
B 1 84  SER 84  84  ?   ?   ?   B . n 
B 1 85  SER 85  85  ?   ?   ?   B . n 
B 1 86  SER 86  86  ?   ?   ?   B . n 
B 1 87  THR 87  87  ?   ?   ?   B . n 
B 1 88  VAL 88  88  ?   ?   ?   B . n 
B 1 89  ASP 89  89  ?   ?   ?   B . n 
B 1 90  SER 90  90  ?   ?   ?   B . n 
B 1 91  LYS 91  91  ?   ?   ?   B . n 
B 1 92  ASP 92  92  ?   ?   ?   B . n 
B 1 93  GLU 93  93  ?   ?   ?   B . n 
B 1 94  ASP 94  94  ?   ?   ?   B . n 
B 1 95  HIS 95  95  ?   ?   ?   B . n 
B 1 96  TYR 96  96  ?   ?   ?   B . n 
B 1 97  SER 97  97  ?   ?   ?   B . n 
B 1 98  LYS 98  98  ?   ?   ?   B . n 
B 1 99  CYS 99  99  ?   ?   ?   B . n 
B 1 100 GLN 100 100 ?   ?   ?   B . n 
B 1 101 ASP 101 101 ?   ?   ?   B . n 
B 1 102 CYS 102 102 ?   ?   ?   B . n 
B 1 103 ILE 103 103 ?   ?   ?   B . n 
B 1 104 HIS 104 104 ?   ?   ?   B . n 
B 1 105 ARG 105 105 ?   ?   ?   B . n 
B 1 106 LEU 106 106 ?   ?   ?   B . n 
B 1 107 GLY 107 107 ?   ?   ?   B . n 
B 1 108 GLN 108 108 ?   ?   ?   B . n 
B 1 109 VAL 109 109 ?   ?   ?   B . n 
B 1 110 VAL 110 110 ?   ?   ?   B . n 
B 1 111 ARG 111 111 ?   ?   ?   B . n 
B 1 112 ARG 112 112 ?   ?   ?   B . n 
B 1 113 LYS 113 113 ?   ?   ?   B . n 
B 1 114 LEU 114 114 ?   ?   ?   B . n 
B 1 115 GLY 115 115 115 GLY GLY B . n 
B 1 116 GLU 116 116 116 GLU GLU B . n 
B 1 117 ASP 117 117 117 ASP ASP B . n 
B 1 118 GLY 118 118 118 GLY GLY B . n 
B 1 119 ILE 119 119 119 ILE ILE B . n 
B 1 120 PHE 120 120 120 PHE PHE B . n 
B 1 121 LEU 121 121 121 LEU LEU B . n 
B 1 122 VAL 122 122 122 VAL VAL B . n 
B 1 123 LEU 123 123 123 LEU LEU B . n 
B 1 124 LEU 124 124 124 LEU LEU B . n 
B 1 125 GLY 125 125 125 GLY GLY B . n 
B 1 126 LEU 126 126 126 LEU LEU B . n 
B 1 127 LEU 127 127 127 LEU LEU B . n 
B 1 128 MET 128 128 128 MET MET B . n 
B 1 129 ALA 129 129 129 ALA ALA B . n 
B 1 130 LEU 130 130 130 LEU LEU B . n 
B 1 131 VAL 131 131 131 VAL VAL B . n 
B 1 132 SER 132 132 132 SER SER B . n 
B 1 133 TRP 133 133 133 TRP TRP B . n 
B 1 134 SER 134 134 134 SER SER B . n 
B 1 135 MET 135 135 135 MET MET B . n 
B 1 136 GLY 136 136 136 GLY GLY B . n 
B 1 137 TYR 137 137 137 TYR TYR B . n 
B 1 138 VAL 138 138 138 VAL VAL B . n 
B 1 139 SER 139 139 139 SER SER B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 LYS 141 141 141 LYS LYS B . n 
B 1 142 SER 142 142 142 SER SER B . n 
B 1 143 LEU 143 143 143 LEU LEU B . n 
B 1 144 GLN 144 144 144 GLN GLN B . n 
B 1 145 ALA 145 145 145 ALA ALA B . n 
B 1 146 TYR 146 146 146 TYR TYR B . n 
B 1 147 LYS 147 147 147 LYS LYS B . n 
B 1 148 TRP 148 148 148 TRP TRP B . n 
B 1 149 SER 149 149 149 SER SER B . n 
B 1 150 TYR 150 150 150 TYR TYR B . n 
B 1 151 ALA 151 151 151 ALA ALA B . n 
B 1 152 GLN 152 152 152 GLN GLN B . n 
B 1 153 MET 153 153 153 MET MET B . n 
B 1 154 GLN 154 154 154 GLN GLN B . n 
B 1 155 PRO 155 155 155 PRO PRO B . n 
B 1 156 SER 156 156 156 SER SER B . n 
B 1 157 LEU 157 157 157 LEU LEU B . n 
B 1 158 PRO 158 158 158 PRO PRO B . n 
B 1 159 LEU 159 159 159 LEU LEU B . n 
B 1 160 GLN 160 160 160 GLN GLN B . n 
B 1 161 PHE 161 161 161 PHE PHE B . n 
B 1 162 LEU 162 162 162 LEU LEU B . n 
B 1 163 VAL 163 163 163 VAL VAL B . n 
B 1 164 TRP 164 164 164 TRP TRP B . n 
B 1 165 VAL 165 165 165 VAL VAL B . n 
B 1 166 THR 166 166 166 THR THR B . n 
B 1 167 PHE 167 167 167 PHE PHE B . n 
B 1 168 PRO 168 168 168 PRO PRO B . n 
B 1 169 LEU 169 169 169 LEU LEU B . n 
B 1 170 VAL 170 170 170 VAL VAL B . n 
B 1 171 LEU 171 171 171 LEU LEU B . n 
B 1 172 ILE 172 172 172 ILE ILE B . n 
B 1 173 LEU 173 173 173 LEU LEU B . n 
B 1 174 PHE 174 174 174 PHE PHE B . n 
B 1 175 SER 175 175 175 SER SER B . n 
B 1 176 ALA 176 176 176 ALA ALA B . n 
B 1 177 LEU 177 177 177 LEU LEU B . n 
B 1 178 PHE 178 178 178 PHE PHE B . n 
B 1 179 CYS 179 179 179 CYS CYS B . n 
B 1 180 HIS 180 180 180 HIS HIS B . n 
B 1 181 LEU 181 181 181 LEU LEU B . n 
B 1 182 ILE 182 182 182 ILE ILE B . n 
B 1 183 SER 183 183 183 SER SER B . n 
B 1 184 PRO 184 184 184 PRO PRO B . n 
B 1 185 GLN 185 185 185 GLN GLN B . n 
B 1 186 ALA 186 186 186 ALA ALA B . n 
B 1 187 VAL 187 187 187 VAL VAL B . n 
B 1 188 GLY 188 188 188 GLY GLY B . n 
B 1 189 SER 189 189 189 SER SER B . n 
B 1 190 GLY 190 190 190 GLY GLY B . n 
B 1 191 ILE 191 191 191 ILE ILE B . n 
B 1 192 PRO 192 192 192 PRO PRO B . n 
B 1 193 GLU 193 193 193 GLU GLU B . n 
B 1 194 MET 194 194 194 MET MET B . n 
B 1 195 LYS 195 195 195 LYS LYS B . n 
B 1 196 THR 196 196 196 THR THR B . n 
B 1 197 ILE 197 197 197 ILE ILE B . n 
B 1 198 LEU 198 198 198 LEU LEU B . n 
B 1 199 ARG 199 199 199 ARG ARG B . n 
B 1 200 GLY 200 200 200 GLY GLY B . n 
B 1 201 VAL 201 201 201 VAL VAL B . n 
B 1 202 VAL 202 202 202 VAL VAL B . n 
B 1 203 LEU 203 203 203 LEU LEU B . n 
B 1 204 LYS 204 204 204 LYS LYS B . n 
B 1 205 GLU 205 205 205 GLU GLU B . n 
B 1 206 TYR 206 206 206 TYR TYR B . n 
B 1 207 LEU 207 207 207 LEU LEU B . n 
B 1 208 THR 208 208 208 THR THR B . n 
B 1 209 MET 209 209 209 MET MET B . n 
B 1 210 LYS 210 210 210 LYS LYS B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 PHE 212 212 212 PHE PHE B . n 
B 1 213 VAL 213 213 213 VAL VAL B . n 
B 1 214 ALA 214 214 214 ALA ALA B . n 
B 1 215 LYS 215 215 215 LYS LYS B . n 
B 1 216 VAL 216 216 216 VAL VAL B . n 
B 1 217 VAL 217 217 217 VAL VAL B . n 
B 1 218 ALA 218 218 218 ALA ALA B . n 
B 1 219 LEU 219 219 219 LEU LEU B . n 
B 1 220 THR 220 220 220 THR THR B . n 
B 1 221 ALA 221 221 221 ALA ALA B . n 
B 1 222 GLY 222 222 222 GLY GLY B . n 
B 1 223 LEU 223 223 223 LEU LEU B . n 
B 1 224 GLY 224 224 224 GLY GLY B . n 
B 1 225 SER 225 225 225 SER SER B . n 
B 1 226 GLY 226 226 226 GLY GLY B . n 
B 1 227 ILE 227 227 227 ILE ILE B . n 
B 1 228 PRO 228 228 228 PRO PRO B . n 
B 1 229 VAL 229 229 229 VAL VAL B . n 
B 1 230 GLY 230 230 230 GLY GLY B . n 
B 1 231 LYS 231 231 231 LYS LYS B . n 
B 1 232 GLU 232 232 232 GLU GLU B . n 
B 1 233 GLY 233 233 233 GLY GLY B . n 
B 1 234 PRO 234 234 234 PRO PRO B . n 
B 1 235 PHE 235 235 235 PHE PHE B . n 
B 1 236 VAL 236 236 236 VAL VAL B . n 
B 1 237 HIS 237 237 237 HIS HIS B . n 
B 1 238 ILE 238 238 238 ILE ILE B . n 
B 1 239 ALA 239 239 239 ALA ALA B . n 
B 1 240 SER 240 240 240 SER SER B . n 
B 1 241 ILE 241 241 241 ILE ILE B . n 
B 1 242 CYS 242 242 242 CYS CYS B . n 
B 1 243 ALA 243 243 243 ALA ALA B . n 
B 1 244 ALA 244 244 244 ALA ALA B . n 
B 1 245 VAL 245 245 245 VAL VAL B . n 
B 1 246 LEU 246 246 246 LEU LEU B . n 
B 1 247 SER 247 247 247 SER SER B . n 
B 1 248 LYS 248 248 248 LYS LYS B . n 
B 1 249 PHE 249 249 249 PHE PHE B . n 
B 1 250 MET 250 250 250 MET MET B . n 
B 1 251 SER 251 251 251 SER SER B . n 
B 1 252 VAL 252 252 252 VAL VAL B . n 
B 1 253 PHE 253 253 253 PHE PHE B . n 
B 1 254 CYS 254 254 ?   ?   ?   B . n 
B 1 255 GLY 255 255 ?   ?   ?   B . n 
B 1 256 VAL 256 256 ?   ?   ?   B . n 
B 1 257 TYR 257 257 ?   ?   ?   B . n 
B 1 258 GLU 258 258 ?   ?   ?   B . n 
B 1 259 GLN 259 259 ?   ?   ?   B . n 
B 1 260 PRO 260 260 ?   ?   ?   B . n 
B 1 261 TYR 261 261 ?   ?   ?   B . n 
B 1 262 TYR 262 262 262 TYR TYR B . n 
B 1 263 TYR 263 263 263 TYR TYR B . n 
B 1 264 SER 264 264 264 SER SER B . n 
B 1 265 ASP 265 265 265 ASP ASP B . n 
B 1 266 ILE 266 266 266 ILE ILE B . n 
B 1 267 LEU 267 267 267 LEU LEU B . n 
B 1 268 THR 268 268 268 THR THR B . n 
B 1 269 VAL 269 269 269 VAL VAL B . n 
B 1 270 GLY 270 270 270 GLY GLY B . n 
B 1 271 CYS 271 271 271 CYS CYS B . n 
B 1 272 ALA 272 272 272 ALA ALA B . n 
B 1 273 VAL 273 273 273 VAL VAL B . n 
B 1 274 GLY 274 274 274 GLY GLY B . n 
B 1 275 VAL 275 275 275 VAL VAL B . n 
B 1 276 GLY 276 276 276 GLY GLY B . n 
B 1 277 CYS 277 277 277 CYS CYS B . n 
B 1 278 CYS 278 278 278 CYS CYS B . n 
B 1 279 PHE 279 279 279 PHE PHE B . n 
B 1 280 GLY 280 280 280 GLY GLY B . n 
B 1 281 THR 281 281 281 THR THR B . n 
B 1 282 PRO 282 282 282 PRO PRO B . n 
B 1 283 LEU 283 283 283 LEU LEU B . n 
B 1 284 GLY 284 284 284 GLY GLY B . n 
B 1 285 GLY 285 285 285 GLY GLY B . n 
B 1 286 VAL 286 286 286 VAL VAL B . n 
B 1 287 LEU 287 287 287 LEU LEU B . n 
B 1 288 PHE 288 288 288 PHE PHE B . n 
B 1 289 SER 289 289 289 SER SER B . n 
B 1 290 ILE 290 290 290 ILE ILE B . n 
B 1 291 GLU 291 291 291 GLU GLU B . n 
B 1 292 VAL 292 292 292 VAL VAL B . n 
B 1 293 THR 293 293 293 THR THR B . n 
B 1 294 SER 294 294 294 SER SER B . n 
B 1 295 THR 295 295 295 THR THR B . n 
B 1 296 TYR 296 296 296 TYR TYR B . n 
B 1 297 PHE 297 297 297 PHE PHE B . n 
B 1 298 ALA 298 298 298 ALA ALA B . n 
B 1 299 VAL 299 299 299 VAL VAL B . n 
B 1 300 ARG 300 300 300 ARG ARG B . n 
B 1 301 ASN 301 301 301 ASN ASN B . n 
B 1 302 TYR 302 302 302 TYR TYR B . n 
B 1 303 TRP 303 303 303 TRP TRP B . n 
B 1 304 ARG 304 304 304 ARG ARG B . n 
B 1 305 GLY 305 305 305 GLY GLY B . n 
B 1 306 PHE 306 306 306 PHE PHE B . n 
B 1 307 PHE 307 307 307 PHE PHE B . n 
B 1 308 ALA 308 308 308 ALA ALA B . n 
B 1 309 ALA 309 309 309 ALA ALA B . n 
B 1 310 THR 310 310 310 THR THR B . n 
B 1 311 PHE 311 311 311 PHE PHE B . n 
B 1 312 SER 312 312 312 SER SER B . n 
B 1 313 ALA 313 313 313 ALA ALA B . n 
B 1 314 PHE 314 314 314 PHE PHE B . n 
B 1 315 VAL 315 315 315 VAL VAL B . n 
B 1 316 PHE 316 316 316 PHE PHE B . n 
B 1 317 ARG 317 317 317 ARG ARG B . n 
B 1 318 VAL 318 318 318 VAL VAL B . n 
B 1 319 LEU 319 319 319 LEU LEU B . n 
B 1 320 ALA 320 320 320 ALA ALA B . n 
B 1 321 VAL 321 321 321 VAL VAL B . n 
B 1 322 TRP 322 322 322 TRP TRP B . n 
B 1 323 ASN 323 323 323 ASN ASN B . n 
B 1 324 LYS 324 324 324 LYS LYS B . n 
B 1 325 ASP 325 325 325 ASP ASP B . n 
B 1 326 ALA 326 326 326 ALA ALA B . n 
B 1 327 VAL 327 327 327 VAL VAL B . n 
B 1 328 THR 328 328 328 THR THR B . n 
B 1 329 ILE 329 329 329 ILE ILE B . n 
B 1 330 THR 330 330 330 THR THR B . n 
B 1 331 ALA 331 331 331 ALA ALA B . n 
B 1 332 LEU 332 332 332 LEU LEU B . n 
B 1 333 PHE 333 333 333 PHE PHE B . n 
B 1 334 ARG 334 334 334 ARG ARG B . n 
B 1 335 THR 335 335 335 THR THR B . n 
B 1 336 ASN 336 336 336 ASN ASN B . n 
B 1 337 PHE 337 337 337 PHE PHE B . n 
B 1 338 ARG 338 338 338 ARG ARG B . n 
B 1 339 MET 339 339 339 MET MET B . n 
B 1 340 ASP 340 340 340 ASP ASP B . n 
B 1 341 PHE 341 341 341 PHE PHE B . n 
B 1 342 PRO 342 342 342 PRO PRO B . n 
B 1 343 PHE 343 343 343 PHE PHE B . n 
B 1 344 ASP 344 344 344 ASP ASP B . n 
B 1 345 LEU 345 345 345 LEU LEU B . n 
B 1 346 LYS 346 346 346 LYS LYS B . n 
B 1 347 GLU 347 347 347 GLU GLU B . n 
B 1 348 LEU 348 348 348 LEU LEU B . n 
B 1 349 PRO 349 349 349 PRO PRO B . n 
B 1 350 ALA 350 350 350 ALA ALA B . n 
B 1 351 PHE 351 351 351 PHE PHE B . n 
B 1 352 ALA 352 352 352 ALA ALA B . n 
B 1 353 ALA 353 353 353 ALA ALA B . n 
B 1 354 ILE 354 354 354 ILE ILE B . n 
B 1 355 GLY 355 355 355 GLY GLY B . n 
B 1 356 ILE 356 356 356 ILE ILE B . n 
B 1 357 CYS 357 357 357 CYS CYS B . n 
B 1 358 CYS 358 358 358 CYS CYS B . n 
B 1 359 GLY 359 359 359 GLY GLY B . n 
B 1 360 LEU 360 360 360 LEU LEU B . n 
B 1 361 LEU 361 361 361 LEU LEU B . n 
B 1 362 GLY 362 362 362 GLY GLY B . n 
B 1 363 ALA 363 363 363 ALA ALA B . n 
B 1 364 VAL 364 364 364 VAL VAL B . n 
B 1 365 PHE 365 365 365 PHE PHE B . n 
B 1 366 VAL 366 366 366 VAL VAL B . n 
B 1 367 TYR 367 367 367 TYR TYR B . n 
B 1 368 LEU 368 368 368 LEU LEU B . n 
B 1 369 HIS 369 369 369 HIS HIS B . n 
B 1 370 ARG 370 370 370 ARG ARG B . n 
B 1 371 GLN 371 371 371 GLN GLN B . n 
B 1 372 VAL 372 372 372 VAL VAL B . n 
B 1 373 MET 373 373 373 MET MET B . n 
B 1 374 LEU 374 374 374 LEU LEU B . n 
B 1 375 GLY 375 375 375 GLY GLY B . n 
B 1 376 VAL 376 376 376 VAL VAL B . n 
B 1 377 ARG 377 377 377 ARG ARG B . n 
B 1 378 LYS 378 378 378 LYS LYS B . n 
B 1 379 HIS 379 379 379 HIS HIS B . n 
B 1 380 LYS 380 380 380 LYS LYS B . n 
B 1 381 ALA 381 381 381 ALA ALA B . n 
B 1 382 LEU 382 382 382 LEU LEU B . n 
B 1 383 SER 383 383 383 SER SER B . n 
B 1 384 GLN 384 384 384 GLN GLN B . n 
B 1 385 PHE 385 385 385 PHE PHE B . n 
B 1 386 LEU 386 386 386 LEU LEU B . n 
B 1 387 ALA 387 387 387 ALA ALA B . n 
B 1 388 LYS 388 388 388 LYS LYS B . n 
B 1 389 HIS 389 389 389 HIS HIS B . n 
B 1 390 ARG 390 390 390 ARG ARG B . n 
B 1 391 LEU 391 391 391 LEU LEU B . n 
B 1 392 LEU 392 392 392 LEU LEU B . n 
B 1 393 TYR 393 393 393 TYR TYR B . n 
B 1 394 PRO 394 394 394 PRO PRO B . n 
B 1 395 GLY 395 395 395 GLY GLY B . n 
B 1 396 ILE 396 396 396 ILE ILE B . n 
B 1 397 VAL 397 397 397 VAL VAL B . n 
B 1 398 THR 398 398 398 THR THR B . n 
B 1 399 PHE 399 399 399 PHE PHE B . n 
B 1 400 VAL 400 400 400 VAL VAL B . n 
B 1 401 ILE 401 401 401 ILE ILE B . n 
B 1 402 ALA 402 402 402 ALA ALA B . n 
B 1 403 SER 403 403 403 SER SER B . n 
B 1 404 PHE 404 404 404 PHE PHE B . n 
B 1 405 THR 405 405 405 THR THR B . n 
B 1 406 PHE 406 406 406 PHE PHE B . n 
B 1 407 PRO 407 407 407 PRO PRO B . n 
B 1 408 PRO 408 408 408 PRO PRO B . n 
B 1 409 GLY 409 409 409 GLY GLY B . n 
B 1 410 MET 410 410 410 MET MET B . n 
B 1 411 GLY 411 411 411 GLY GLY B . n 
B 1 412 GLN 412 412 412 GLN GLN B . n 
B 1 413 PHE 413 413 413 PHE PHE B . n 
B 1 414 MET 414 414 414 MET MET B . n 
B 1 415 ALA 415 415 415 ALA ALA B . n 
B 1 416 GLY 416 416 416 GLY GLY B . n 
B 1 417 GLU 417 417 417 GLU GLU B . n 
B 1 418 LEU 418 418 418 LEU LEU B . n 
B 1 419 MET 419 419 419 MET MET B . n 
B 1 420 PRO 420 420 420 PRO PRO B . n 
B 1 421 ARG 421 421 421 ARG ARG B . n 
B 1 422 GLU 422 422 422 GLU GLU B . n 
B 1 423 ALA 423 423 423 ALA ALA B . n 
B 1 424 ILE 424 424 424 ILE ILE B . n 
B 1 425 SER 425 425 425 SER SER B . n 
B 1 426 THR 426 426 426 THR THR B . n 
B 1 427 LEU 427 427 427 LEU LEU B . n 
B 1 428 PHE 428 428 428 PHE PHE B . n 
B 1 429 ASP 429 429 429 ASP ASP B . n 
B 1 430 ASN 430 430 430 ASN ASN B . n 
B 1 431 ASN 431 431 431 ASN ASN B . n 
B 1 432 THR 432 432 432 THR THR B . n 
B 1 433 TRP 433 433 433 TRP TRP B . n 
B 1 434 VAL 434 434 434 VAL VAL B . n 
B 1 435 LYS 435 435 435 LYS LYS B . n 
B 1 436 HIS 436 436 436 HIS HIS B . n 
B 1 437 ALA 437 437 437 ALA ALA B . n 
B 1 438 GLY 438 438 438 GLY GLY B . n 
B 1 439 ASP 439 439 439 ASP ASP B . n 
B 1 440 PRO 440 440 440 PRO PRO B . n 
B 1 441 GLU 441 441 441 GLU GLU B . n 
B 1 442 SER 442 442 442 SER SER B . n 
B 1 443 LEU 443 443 443 LEU LEU B . n 
B 1 444 GLY 444 444 444 GLY GLY B . n 
B 1 445 GLN 445 445 445 GLN GLN B . n 
B 1 446 SER 446 446 446 SER SER B . n 
B 1 447 ALA 447 447 447 ALA ALA B . n 
B 1 448 VAL 448 448 448 VAL VAL B . n 
B 1 449 TRP 449 449 449 TRP TRP B . n 
B 1 450 ILE 450 450 450 ILE ILE B . n 
B 1 451 HIS 451 451 451 HIS HIS B . n 
B 1 452 PRO 452 452 452 PRO PRO B . n 
B 1 453 ARG 453 453 453 ARG ARG B . n 
B 1 454 VAL 454 454 454 VAL VAL B . n 
B 1 455 ASN 455 455 455 ASN ASN B . n 
B 1 456 VAL 456 456 456 VAL VAL B . n 
B 1 457 VAL 457 457 457 VAL VAL B . n 
B 1 458 ILE 458 458 458 ILE ILE B . n 
B 1 459 ILE 459 459 459 ILE ILE B . n 
B 1 460 ILE 460 460 460 ILE ILE B . n 
B 1 461 PHE 461 461 461 PHE PHE B . n 
B 1 462 LEU 462 462 462 LEU LEU B . n 
B 1 463 PHE 463 463 463 PHE PHE B . n 
B 1 464 PHE 464 464 464 PHE PHE B . n 
B 1 465 VAL 465 465 465 VAL VAL B . n 
B 1 466 MET 466 466 466 MET MET B . n 
B 1 467 LYS 467 467 467 LYS LYS B . n 
B 1 468 PHE 468 468 468 PHE PHE B . n 
B 1 469 TRP 469 469 469 TRP TRP B . n 
B 1 470 MET 470 470 470 MET MET B . n 
B 1 471 SER 471 471 471 SER SER B . n 
B 1 472 ILE 472 472 472 ILE ILE B . n 
B 1 473 VAL 473 473 473 VAL VAL B . n 
B 1 474 ALA 474 474 474 ALA ALA B . n 
B 1 475 THR 475 475 475 THR THR B . n 
B 1 476 THR 476 476 476 THR THR B . n 
B 1 477 MET 477 477 477 MET MET B . n 
B 1 478 PRO 478 478 478 PRO PRO B . n 
B 1 479 ILE 479 479 479 ILE ILE B . n 
B 1 480 PRO 480 480 480 PRO PRO B . n 
B 1 481 CYS 481 481 481 CYS CYS B . n 
B 1 482 GLY 482 482 482 GLY GLY B . n 
B 1 483 GLY 483 483 483 GLY GLY B . n 
B 1 484 PHE 484 484 484 PHE PHE B . n 
B 1 485 MET 485 485 485 MET MET B . n 
B 1 486 PRO 486 486 486 PRO PRO B . n 
B 1 487 VAL 487 487 487 VAL VAL B . n 
B 1 488 PHE 488 488 488 PHE PHE B . n 
B 1 489 VAL 489 489 489 VAL VAL B . n 
B 1 490 LEU 490 490 490 LEU LEU B . n 
B 1 491 GLY 491 491 491 GLY GLY B . n 
B 1 492 ALA 492 492 492 ALA ALA B . n 
B 1 493 ALA 493 493 493 ALA ALA B . n 
B 1 494 PHE 494 494 494 PHE PHE B . n 
B 1 495 GLY 495 495 495 GLY GLY B . n 
B 1 496 ARG 496 496 496 ARG ARG B . n 
B 1 497 LEU 497 497 497 LEU LEU B . n 
B 1 498 VAL 498 498 498 VAL VAL B . n 
B 1 499 GLY 499 499 499 GLY GLY B . n 
B 1 500 GLU 500 500 500 GLU GLU B . n 
B 1 501 ILE 501 501 501 ILE ILE B . n 
B 1 502 MET 502 502 502 MET MET B . n 
B 1 503 ALA 503 503 503 ALA ALA B . n 
B 1 504 MET 504 504 504 MET MET B . n 
B 1 505 LEU 505 505 505 LEU LEU B . n 
B 1 506 PHE 506 506 506 PHE PHE B . n 
B 1 507 PRO 507 507 507 PRO PRO B . n 
B 1 508 ASP 508 508 508 ASP ASP B . n 
B 1 509 GLY 509 509 509 GLY GLY B . n 
B 1 510 ILE 510 510 510 ILE ILE B . n 
B 1 511 LEU 511 511 511 LEU LEU B . n 
B 1 512 PHE 512 512 512 PHE PHE B . n 
B 1 513 ASP 513 513 513 ASP ASP B . n 
B 1 514 ASP 514 514 514 ASP ASP B . n 
B 1 515 ILE 515 515 515 ILE ILE B . n 
B 1 516 ILE 516 516 516 ILE ILE B . n 
B 1 517 TYR 517 517 517 TYR TYR B . n 
B 1 518 LYS 518 518 518 LYS LYS B . n 
B 1 519 ILE 519 519 519 ILE ILE B . n 
B 1 520 LEU 520 520 520 LEU LEU B . n 
B 1 521 PRO 521 521 521 PRO PRO B . n 
B 1 522 GLY 522 522 522 GLY GLY B . n 
B 1 523 GLY 523 523 523 GLY GLY B . n 
B 1 524 TYR 524 524 524 TYR TYR B . n 
B 1 525 ALA 525 525 525 ALA ALA B . n 
B 1 526 VAL 526 526 526 VAL VAL B . n 
B 1 527 ILE 527 527 527 ILE ILE B . n 
B 1 528 GLY 528 528 528 GLY GLY B . n 
B 1 529 ALA 529 529 529 ALA ALA B . n 
B 1 530 ALA 530 530 530 ALA ALA B . n 
B 1 531 ALA 531 531 531 ALA ALA B . n 
B 1 532 LEU 532 532 532 LEU LEU B . n 
B 1 533 THR 533 533 533 THR THR B . n 
B 1 534 GLY 534 534 534 GLY GLY B . n 
B 1 535 ALA 535 535 535 ALA ALA B . n 
B 1 536 VAL 536 536 536 VAL VAL B . n 
B 1 537 SER 537 537 537 SER SER B . n 
B 1 538 HIS 538 538 538 HIS HIS B . n 
B 1 539 THR 539 539 539 THR THR B . n 
B 1 540 VAL 540 540 540 VAL VAL B . n 
B 1 541 SER 541 541 541 SER SER B . n 
B 1 542 THR 542 542 542 THR THR B . n 
B 1 543 ALA 543 543 543 ALA ALA B . n 
B 1 544 VAL 544 544 544 VAL VAL B . n 
B 1 545 ILE 545 545 545 ILE ILE B . n 
B 1 546 CYS 546 546 546 CYS CYS B . n 
B 1 547 PHE 547 547 547 PHE PHE B . n 
B 1 548 GLU 548 548 548 GLU GLU B . n 
B 1 549 LEU 549 549 549 LEU LEU B . n 
B 1 550 THR 550 550 550 THR THR B . n 
B 1 551 GLY 551 551 551 GLY GLY B . n 
B 1 552 GLN 552 552 552 GLN GLN B . n 
B 1 553 ILE 553 553 553 ILE ILE B . n 
B 1 554 ALA 554 554 554 ALA ALA B . n 
B 1 555 HIS 555 555 555 HIS HIS B . n 
B 1 556 ILE 556 556 556 ILE ILE B . n 
B 1 557 LEU 557 557 557 LEU LEU B . n 
B 1 558 PRO 558 558 558 PRO PRO B . n 
B 1 559 MET 559 559 559 MET MET B . n 
B 1 560 MET 560 560 560 MET MET B . n 
B 1 561 VAL 561 561 561 VAL VAL B . n 
B 1 562 ALA 562 562 562 ALA ALA B . n 
B 1 563 VAL 563 563 563 VAL VAL B . n 
B 1 564 ILE 564 564 564 ILE ILE B . n 
B 1 565 LEU 565 565 565 LEU LEU B . n 
B 1 566 ALA 566 566 566 ALA ALA B . n 
B 1 567 ASN 567 567 567 ASN ASN B . n 
B 1 568 MET 568 568 568 MET MET B . n 
B 1 569 VAL 569 569 569 VAL VAL B . n 
B 1 570 ALA 570 570 570 ALA ALA B . n 
B 1 571 GLN 571 571 571 GLN GLN B . n 
B 1 572 SER 572 572 572 SER SER B . n 
B 1 573 LEU 573 573 573 LEU LEU B . n 
B 1 574 GLN 574 574 574 GLN GLN B . n 
B 1 575 PRO 575 575 575 PRO PRO B . n 
B 1 576 SER 576 576 576 SER SER B . n 
B 1 577 LEU 577 577 577 LEU LEU B . n 
B 1 578 TYR 578 578 578 TYR TYR B . n 
B 1 579 ASP 579 579 579 ASP ASP B . n 
B 1 580 SER 580 580 580 SER SER B . n 
B 1 581 ILE 581 581 581 ILE ILE B . n 
B 1 582 ILE 582 582 582 ILE ILE B . n 
B 1 583 GLN 583 583 583 GLN GLN B . n 
B 1 584 VAL 584 584 584 VAL VAL B . n 
B 1 585 LYS 585 585 585 LYS LYS B . n 
B 1 586 LYS 586 586 586 LYS LYS B . n 
B 1 587 LEU 587 587 587 LEU LEU B . n 
B 1 588 PRO 588 588 588 PRO PRO B . n 
B 1 589 TYR 589 589 589 TYR TYR B . n 
B 1 590 LEU 590 590 ?   ?   ?   B . n 
B 1 591 PRO 591 591 ?   ?   ?   B . n 
B 1 592 ASP 592 592 ?   ?   ?   B . n 
B 1 593 LEU 593 593 ?   ?   ?   B . n 
B 1 594 GLY 594 594 ?   ?   ?   B . n 
B 1 595 TRP 595 595 ?   ?   ?   B . n 
B 1 596 ASN 596 596 ?   ?   ?   B . n 
B 1 597 GLN 597 597 ?   ?   ?   B . n 
B 1 598 LEU 598 598 ?   ?   ?   B . n 
B 1 599 SER 599 599 ?   ?   ?   B . n 
B 1 600 LYS 600 600 ?   ?   ?   B . n 
B 1 601 TYR 601 601 ?   ?   ?   B . n 
B 1 602 THR 602 602 ?   ?   ?   B . n 
B 1 603 ILE 603 603 ?   ?   ?   B . n 
B 1 604 PHE 604 604 ?   ?   ?   B . n 
B 1 605 VAL 605 605 ?   ?   ?   B . n 
B 1 606 GLU 606 606 ?   ?   ?   B . n 
B 1 607 ASP 607 607 ?   ?   ?   B . n 
B 1 608 ILE 608 608 ?   ?   ?   B . n 
B 1 609 MET 609 609 ?   ?   ?   B . n 
B 1 610 VAL 610 610 ?   ?   ?   B . n 
B 1 611 ARG 611 611 ?   ?   ?   B . n 
B 1 612 ASP 612 612 ?   ?   ?   B . n 
B 1 613 VAL 613 613 ?   ?   ?   B . n 
B 1 614 LYS 614 614 ?   ?   ?   B . n 
B 1 615 PHE 615 615 ?   ?   ?   B . n 
B 1 616 VAL 616 616 ?   ?   ?   B . n 
B 1 617 SER 617 617 ?   ?   ?   B . n 
B 1 618 ALA 618 618 ?   ?   ?   B . n 
B 1 619 SER 619 619 ?   ?   ?   B . n 
B 1 620 TYR 620 620 ?   ?   ?   B . n 
B 1 621 THR 621 621 ?   ?   ?   B . n 
B 1 622 TYR 622 622 ?   ?   ?   B . n 
B 1 623 GLY 623 623 ?   ?   ?   B . n 
B 1 624 GLU 624 624 ?   ?   ?   B . n 
B 1 625 LEU 625 625 ?   ?   ?   B . n 
B 1 626 ARG 626 626 ?   ?   ?   B . n 
B 1 627 THR 627 627 ?   ?   ?   B . n 
B 1 628 LEU 628 628 ?   ?   ?   B . n 
B 1 629 LEU 629 629 ?   ?   ?   B . n 
B 1 630 GLN 630 630 ?   ?   ?   B . n 
B 1 631 THR 631 631 ?   ?   ?   B . n 
B 1 632 THR 632 632 ?   ?   ?   B . n 
B 1 633 THR 633 633 ?   ?   ?   B . n 
B 1 634 VAL 634 634 ?   ?   ?   B . n 
B 1 635 LYS 635 635 ?   ?   ?   B . n 
B 1 636 THR 636 636 ?   ?   ?   B . n 
B 1 637 LEU 637 637 ?   ?   ?   B . n 
B 1 638 PRO 638 638 ?   ?   ?   B . n 
B 1 639 LEU 639 639 ?   ?   ?   B . n 
B 1 640 VAL 640 640 ?   ?   ?   B . n 
B 1 641 ASP 641 641 ?   ?   ?   B . n 
B 1 642 SER 642 642 ?   ?   ?   B . n 
B 1 643 LYS 643 643 ?   ?   ?   B . n 
B 1 644 ASP 644 644 ?   ?   ?   B . n 
B 1 645 SER 645 645 ?   ?   ?   B . n 
B 1 646 MET 646 646 ?   ?   ?   B . n 
B 1 647 ILE 647 647 ?   ?   ?   B . n 
B 1 648 LEU 648 648 ?   ?   ?   B . n 
B 1 649 LEU 649 649 ?   ?   ?   B . n 
B 1 650 GLY 650 650 ?   ?   ?   B . n 
B 1 651 SER 651 651 ?   ?   ?   B . n 
B 1 652 VAL 652 652 ?   ?   ?   B . n 
B 1 653 GLU 653 653 ?   ?   ?   B . n 
B 1 654 ARG 654 654 ?   ?   ?   B . n 
B 1 655 SER 655 655 ?   ?   ?   B . n 
B 1 656 GLU 656 656 ?   ?   ?   B . n 
B 1 657 LEU 657 657 ?   ?   ?   B . n 
B 1 658 GLN 658 658 ?   ?   ?   B . n 
B 1 659 ALA 659 659 ?   ?   ?   B . n 
B 1 660 LEU 660 660 ?   ?   ?   B . n 
B 1 661 LEU 661 661 ?   ?   ?   B . n 
B 1 662 GLN 662 662 ?   ?   ?   B . n 
B 1 663 ARG 663 663 ?   ?   ?   B . n 
B 1 664 HIS 664 664 ?   ?   ?   B . n 
B 1 665 LEU 665 665 ?   ?   ?   B . n 
B 1 666 CYS 666 666 ?   ?   ?   B . n 
B 1 667 PRO 667 667 ?   ?   ?   B . n 
B 1 668 GLU 668 668 ?   ?   ?   B . n 
B 1 669 ARG 669 669 ?   ?   ?   B . n 
B 1 670 ARG 670 670 ?   ?   ?   B . n 
B 1 671 LEU 671 671 ?   ?   ?   B . n 
B 1 672 ARG 672 672 ?   ?   ?   B . n 
B 1 673 ALA 673 673 ?   ?   ?   B . n 
B 1 674 ALA 674 674 ?   ?   ?   B . n 
B 1 675 GLN 675 675 ?   ?   ?   B . n 
B 1 676 GLU 676 676 ?   ?   ?   B . n 
B 1 677 MET 677 677 ?   ?   ?   B . n 
B 1 678 ALA 678 678 ?   ?   ?   B . n 
B 1 679 ARG 679 679 ?   ?   ?   B . n 
B 1 680 LYS 680 680 ?   ?   ?   B . n 
B 1 681 LEU 681 681 ?   ?   ?   B . n 
B 1 682 SER 682 682 ?   ?   ?   B . n 
B 1 683 GLU 683 683 ?   ?   ?   B . n 
B 1 684 LEU 684 684 ?   ?   ?   B . n 
B 1 685 PRO 685 685 ?   ?   ?   B . n 
B 1 686 TYR 686 686 ?   ?   ?   B . n 
B 1 687 ASP 687 687 ?   ?   ?   B . n 
B 1 688 GLY 688 688 ?   ?   ?   B . n 
B 1 689 LYS 689 689 ?   ?   ?   B . n 
B 1 690 ALA 690 690 ?   ?   ?   B . n 
B 1 691 ARG 691 691 ?   ?   ?   B . n 
B 1 692 LEU 692 692 ?   ?   ?   B . n 
B 1 693 ALA 693 693 ?   ?   ?   B . n 
B 1 694 GLY 694 694 ?   ?   ?   B . n 
B 1 695 GLU 695 695 ?   ?   ?   B . n 
B 1 696 GLY 696 696 ?   ?   ?   B . n 
B 1 697 LEU 697 697 ?   ?   ?   B . n 
B 1 698 PRO 698 698 ?   ?   ?   B . n 
B 1 699 GLY 699 699 ?   ?   ?   B . n 
B 1 700 ALA 700 700 ?   ?   ?   B . n 
B 1 701 PRO 701 701 ?   ?   ?   B . n 
B 1 702 PRO 702 702 ?   ?   ?   B . n 
B 1 703 GLY 703 703 ?   ?   ?   B . n 
B 1 704 ARG 704 704 ?   ?   ?   B . n 
B 1 705 PRO 705 705 ?   ?   ?   B . n 
B 1 706 GLU 706 706 ?   ?   ?   B . n 
B 1 707 SER 707 707 ?   ?   ?   B . n 
B 1 708 PHE 708 708 ?   ?   ?   B . n 
B 1 709 ALA 709 709 ?   ?   ?   B . n 
B 1 710 PHE 710 710 ?   ?   ?   B . n 
B 1 711 VAL 711 711 ?   ?   ?   B . n 
B 1 712 ASP 712 712 ?   ?   ?   B . n 
B 1 713 GLU 713 713 ?   ?   ?   B . n 
B 1 714 ASP 714 714 ?   ?   ?   B . n 
B 1 715 GLU 715 715 ?   ?   ?   B . n 
B 1 716 ASP 716 716 ?   ?   ?   B . n 
B 1 717 GLU 717 717 ?   ?   ?   B . n 
B 1 718 ASP 718 718 ?   ?   ?   B . n 
B 1 719 LEU 719 719 ?   ?   ?   B . n 
B 1 720 SER 720 720 ?   ?   ?   B . n 
B 1 721 GLY 721 721 ?   ?   ?   B . n 
B 1 722 LYS 722 722 ?   ?   ?   B . n 
B 1 723 SER 723 723 ?   ?   ?   B . n 
B 1 724 GLU 724 724 ?   ?   ?   B . n 
B 1 725 LEU 725 725 ?   ?   ?   B . n 
B 1 726 PRO 726 726 ?   ?   ?   B . n 
B 1 727 PRO 727 727 ?   ?   ?   B . n 
B 1 728 SER 728 728 ?   ?   ?   B . n 
B 1 729 LEU 729 729 ?   ?   ?   B . n 
B 1 730 ALA 730 730 ?   ?   ?   B . n 
B 1 731 LEU 731 731 ?   ?   ?   B . n 
B 1 732 HIS 732 732 ?   ?   ?   B . n 
B 1 733 PRO 733 733 ?   ?   ?   B . n 
B 1 734 SER 734 734 ?   ?   ?   B . n 
B 1 735 THR 735 735 ?   ?   ?   B . n 
B 1 736 THR 736 736 ?   ?   ?   B . n 
B 1 737 ALA 737 737 ?   ?   ?   B . n 
B 1 738 PRO 738 738 ?   ?   ?   B . n 
B 1 739 LEU 739 739 ?   ?   ?   B . n 
B 1 740 SER 740 740 ?   ?   ?   B . n 
B 1 741 PRO 741 741 ?   ?   ?   B . n 
B 1 742 GLU 742 742 ?   ?   ?   B . n 
B 1 743 GLU 743 743 ?   ?   ?   B . n 
B 1 744 PRO 744 744 ?   ?   ?   B . n 
B 1 745 ASN 745 745 ?   ?   ?   B . n 
B 1 746 GLY 746 746 ?   ?   ?   B . n 
B 1 747 PRO 747 747 ?   ?   ?   B . n 
B 1 748 LEU 748 748 ?   ?   ?   B . n 
B 1 749 PRO 749 749 ?   ?   ?   B . n 
B 1 750 GLY 750 750 ?   ?   ?   B . n 
B 1 751 HIS 751 751 ?   ?   ?   B . n 
B 1 752 LYS 752 752 ?   ?   ?   B . n 
B 1 753 GLN 753 753 ?   ?   ?   B . n 
B 1 754 GLN 754 754 ?   ?   ?   B . n 
B 1 755 PRO 755 755 ?   ?   ?   B . n 
B 1 756 GLU 756 756 ?   ?   ?   B . n 
B 1 757 ALA 757 757 ?   ?   ?   B . n 
B 1 758 PRO 758 758 ?   ?   ?   B . n 
B 1 759 GLU 759 759 ?   ?   ?   B . n 
B 1 760 PRO 760 760 ?   ?   ?   B . n 
B 1 761 ALA 761 761 ?   ?   ?   B . n 
B 1 762 GLY 762 762 ?   ?   ?   B . n 
B 1 763 GLN 763 763 ?   ?   ?   B . n 
B 1 764 ARG 764 764 ?   ?   ?   B . n 
B 1 765 PRO 765 765 ?   ?   ?   B . n 
B 1 766 SER 766 766 ?   ?   ?   B . n 
B 1 767 ILE 767 767 ?   ?   ?   B . n 
B 1 768 PHE 768 768 ?   ?   ?   B . n 
B 1 769 GLN 769 769 ?   ?   ?   B . n 
B 1 770 SER 770 770 ?   ?   ?   B . n 
B 1 771 LEU 771 771 ?   ?   ?   B . n 
B 1 772 LEU 772 772 ?   ?   ?   B . n 
B 1 773 HIS 773 773 ?   ?   ?   B . n 
B 1 774 CYS 774 774 ?   ?   ?   B . n 
B 1 775 LEU 775 775 ?   ?   ?   B . n 
B 1 776 LEU 776 776 ?   ?   ?   B . n 
B 1 777 GLY 777 777 ?   ?   ?   B . n 
B 1 778 ARG 778 778 ?   ?   ?   B . n 
B 1 779 ALA 779 779 ?   ?   ?   B . n 
B 1 780 ARG 780 780 ?   ?   ?   B . n 
B 1 781 PRO 781 781 ?   ?   ?   B . n 
B 1 782 THR 782 782 ?   ?   ?   B . n 
B 1 783 LYS 783 783 ?   ?   ?   B . n 
B 1 784 LYS 784 784 ?   ?   ?   B . n 
B 1 785 LYS 785 785 ?   ?   ?   B . n 
B 1 786 THR 786 786 ?   ?   ?   B . n 
B 1 787 THR 787 787 ?   ?   ?   B . n 
B 1 788 GLN 788 788 ?   ?   ?   B . n 
B 1 789 ASP 789 789 ?   ?   ?   B . n 
B 1 790 SER 790 790 ?   ?   ?   B . n 
B 1 791 THR 791 791 ?   ?   ?   B . n 
B 1 792 ASP 792 792 ?   ?   ?   B . n 
B 1 793 LEU 793 793 ?   ?   ?   B . n 
B 1 794 VAL 794 794 ?   ?   ?   B . n 
B 1 795 ASP 795 795 ?   ?   ?   B . n 
B 1 796 ASN 796 796 ?   ?   ?   B . n 
B 1 797 MET 797 797 ?   ?   ?   B . n 
B 1 798 SER 798 798 ?   ?   ?   B . n 
B 1 799 PRO 799 799 ?   ?   ?   B . n 
B 1 800 GLU 800 800 ?   ?   ?   B . n 
B 1 801 GLU 801 801 ?   ?   ?   B . n 
B 1 802 ILE 802 802 ?   ?   ?   B . n 
B 1 803 GLU 803 803 ?   ?   ?   B . n 
B 1 804 ALA 804 804 ?   ?   ?   B . n 
B 1 805 TRP 805 805 ?   ?   ?   B . n 
B 1 806 GLU 806 806 ?   ?   ?   B . n 
B 1 807 GLN 807 807 ?   ?   ?   B . n 
B 1 808 GLU 808 808 ?   ?   ?   B . n 
B 1 809 GLN 809 809 ?   ?   ?   B . n 
B 1 810 LEU 810 810 ?   ?   ?   B . n 
B 1 811 SER 811 811 ?   ?   ?   B . n 
B 1 812 GLN 812 812 ?   ?   ?   B . n 
B 1 813 PRO 813 813 ?   ?   ?   B . n 
B 1 814 VAL 814 814 ?   ?   ?   B . n 
B 1 815 CYS 815 815 ?   ?   ?   B . n 
B 1 816 PHE 816 816 ?   ?   ?   B . n 
B 1 817 ASP 817 817 ?   ?   ?   B . n 
B 1 818 SER 818 818 ?   ?   ?   B . n 
B 1 819 CYS 819 819 ?   ?   ?   B . n 
B 1 820 CYS 820 820 ?   ?   ?   B . n 
B 1 821 ILE 821 821 ?   ?   ?   B . n 
B 1 822 ASP 822 822 ?   ?   ?   B . n 
B 1 823 GLN 823 823 ?   ?   ?   B . n 
B 1 824 SER 824 824 ?   ?   ?   B . n 
B 1 825 PRO 825 825 ?   ?   ?   B . n 
B 1 826 PHE 826 826 ?   ?   ?   B . n 
B 1 827 GLN 827 827 ?   ?   ?   B . n 
B 1 828 LEU 828 828 ?   ?   ?   B . n 
B 1 829 VAL 829 829 ?   ?   ?   B . n 
B 1 830 GLU 830 830 ?   ?   ?   B . n 
B 1 831 GLN 831 831 ?   ?   ?   B . n 
B 1 832 THR 832 832 ?   ?   ?   B . n 
B 1 833 THR 833 833 ?   ?   ?   B . n 
B 1 834 LEU 834 834 ?   ?   ?   B . n 
B 1 835 HIS 835 835 ?   ?   ?   B . n 
B 1 836 LYS 836 836 ?   ?   ?   B . n 
B 1 837 THR 837 837 ?   ?   ?   B . n 
B 1 838 HIS 838 838 ?   ?   ?   B . n 
B 1 839 THR 839 839 ?   ?   ?   B . n 
B 1 840 LEU 840 840 ?   ?   ?   B . n 
B 1 841 PHE 841 841 ?   ?   ?   B . n 
B 1 842 SER 842 842 ?   ?   ?   B . n 
B 1 843 LEU 843 843 ?   ?   ?   B . n 
B 1 844 LEU 844 844 ?   ?   ?   B . n 
B 1 845 GLY 845 845 ?   ?   ?   B . n 
B 1 846 LEU 846 846 ?   ?   ?   B . n 
B 1 847 HIS 847 847 ?   ?   ?   B . n 
B 1 848 LEU 848 848 ?   ?   ?   B . n 
B 1 849 ALA 849 849 ?   ?   ?   B . n 
B 1 850 TYR 850 850 ?   ?   ?   B . n 
B 1 851 VAL 851 851 ?   ?   ?   B . n 
B 1 852 THR 852 852 ?   ?   ?   B . n 
B 1 853 SER 853 853 ?   ?   ?   B . n 
B 1 854 MET 854 854 ?   ?   ?   B . n 
B 1 855 GLY 855 855 ?   ?   ?   B . n 
B 1 856 LYS 856 856 ?   ?   ?   B . n 
B 1 857 LEU 857 857 ?   ?   ?   B . n 
B 1 858 ARG 858 858 ?   ?   ?   B . n 
B 1 859 GLY 859 859 ?   ?   ?   B . n 
B 1 860 VAL 860 860 ?   ?   ?   B . n 
B 1 861 LEU 861 861 ?   ?   ?   B . n 
B 1 862 ALA 862 862 ?   ?   ?   B . n 
B 1 863 LEU 863 863 ?   ?   ?   B . n 
B 1 864 GLU 864 864 ?   ?   ?   B . n 
B 1 865 GLU 865 865 ?   ?   ?   B . n 
B 1 866 LEU 866 866 ?   ?   ?   B . n 
B 1 867 GLN 867 867 ?   ?   ?   B . n 
B 1 868 LYS 868 868 ?   ?   ?   B . n 
B 1 869 ALA 869 869 ?   ?   ?   B . n 
B 1 870 ILE 870 870 ?   ?   ?   B . n 
B 1 871 GLU 871 871 ?   ?   ?   B . n 
B 1 872 GLY 872 872 ?   ?   ?   B . n 
B 1 873 HIS 873 873 ?   ?   ?   B . n 
B 1 874 THR 874 874 ?   ?   ?   B . n 
B 1 875 LYS 875 875 ?   ?   ?   B . n 
B 1 876 SER 876 876 ?   ?   ?   B . n 
B 1 877 GLY 877 877 ?   ?   ?   B . n 
B 1 878 VAL 878 878 ?   ?   ?   B . n 
B 1 879 GLN 879 879 ?   ?   ?   B . n 
B 1 880 LEU 880 880 ?   ?   ?   B . n 
B 1 881 ARG 881 881 ?   ?   ?   B . n 
B 1 882 PRO 882 882 ?   ?   ?   B . n 
B 1 883 PRO 883 883 ?   ?   ?   B . n 
B 1 884 LEU 884 884 ?   ?   ?   B . n 
B 1 885 ALA 885 885 ?   ?   ?   B . n 
B 1 886 SER 886 886 ?   ?   ?   B . n 
B 1 887 PHE 887 887 ?   ?   ?   B . n 
B 1 888 ARG 888 888 ?   ?   ?   B . n 
B 1 889 ASN 889 889 ?   ?   ?   B . n 
B 1 890 THR 890 890 ?   ?   ?   B . n 
B 1 891 THR 891 891 ?   ?   ?   B . n 
B 1 892 SER 892 892 ?   ?   ?   B . n 
B 1 893 THR 893 893 ?   ?   ?   B . n 
B 1 894 ARG 894 894 ?   ?   ?   B . n 
B 1 895 LYS 895 895 ?   ?   ?   B . n 
B 1 896 SER 896 896 ?   ?   ?   B . n 
B 1 897 THR 897 897 ?   ?   ?   B . n 
B 1 898 GLY 898 898 ?   ?   ?   B . n 
B 1 899 ALA 899 899 ?   ?   ?   B . n 
B 1 900 PRO 900 900 ?   ?   ?   B . n 
B 1 901 PRO 901 901 ?   ?   ?   B . n 
B 1 902 SER 902 902 ?   ?   ?   B . n 
B 1 903 SER 903 903 ?   ?   ?   B . n 
B 1 904 ALA 904 904 ?   ?   ?   B . n 
B 1 905 GLU 905 905 ?   ?   ?   B . n 
B 1 906 ASN 906 906 ?   ?   ?   B . n 
B 1 907 TRP 907 907 ?   ?   ?   B . n 
B 1 908 ASN 908 908 ?   ?   ?   B . n 
B 1 909 LEU 909 909 ?   ?   ?   B . n 
B 1 910 PRO 910 910 ?   ?   ?   B . n 
B 1 911 GLU 911 911 ?   ?   ?   B . n 
B 1 912 ASP 912 912 ?   ?   ?   B . n 
B 1 913 ARG 913 913 ?   ?   ?   B . n 
B 1 914 PRO 914 914 ?   ?   ?   B . n 
B 1 915 GLY 915 915 ?   ?   ?   B . n 
B 1 916 ALA 916 916 ?   ?   ?   B . n 
B 1 917 THR 917 917 ?   ?   ?   B . n 
B 1 918 GLY 918 918 ?   ?   ?   B . n 
B 1 919 THR 919 919 ?   ?   ?   B . n 
B 1 920 GLY 920 920 ?   ?   ?   B . n 
B 1 921 ASP 921 921 ?   ?   ?   B . n 
B 1 922 VAL 922 922 ?   ?   ?   B . n 
B 1 923 ILE 923 923 ?   ?   ?   B . n 
B 1 924 ALA 924 924 ?   ?   ?   B . n 
B 1 925 ALA 925 925 ?   ?   ?   B . n 
B 1 926 SER 926 926 ?   ?   ?   B . n 
B 1 927 PRO 927 927 ?   ?   ?   B . n 
B 1 928 GLU 928 928 ?   ?   ?   B . n 
B 1 929 THR 929 929 ?   ?   ?   B . n 
B 1 930 PRO 930 930 ?   ?   ?   B . n 
B 1 931 VAL 931 931 ?   ?   ?   B . n 
B 1 932 PRO 932 932 ?   ?   ?   B . n 
B 1 933 SER 933 933 ?   ?   ?   B . n 
B 1 934 PRO 934 934 ?   ?   ?   B . n 
B 1 935 SER 935 935 ?   ?   ?   B . n 
B 1 936 PRO 936 936 ?   ?   ?   B . n 
B 1 937 GLU 937 937 ?   ?   ?   B . n 
B 1 938 PRO 938 938 ?   ?   ?   B . n 
B 1 939 PRO 939 939 ?   ?   ?   B . n 
B 1 940 LEU 940 940 ?   ?   ?   B . n 
B 1 941 SER 941 941 ?   ?   ?   B . n 
B 1 942 LEU 942 942 ?   ?   ?   B . n 
B 1 943 ALA 943 943 ?   ?   ?   B . n 
B 1 944 PRO 944 944 ?   ?   ?   B . n 
B 1 945 GLY 945 945 ?   ?   ?   B . n 
B 1 946 LYS 946 946 ?   ?   ?   B . n 
B 1 947 VAL 947 947 ?   ?   ?   B . n 
B 1 948 GLU 948 948 ?   ?   ?   B . n 
B 1 949 GLY 949 949 ?   ?   ?   B . n 
B 1 950 GLU 950 950 ?   ?   ?   B . n 
B 1 951 LEU 951 951 ?   ?   ?   B . n 
B 1 952 GLU 952 952 ?   ?   ?   B . n 
B 1 953 GLU 953 953 ?   ?   ?   B . n 
B 1 954 LEU 954 954 ?   ?   ?   B . n 
B 1 955 GLU 955 955 ?   ?   ?   B . n 
B 1 956 LEU 956 956 ?   ?   ?   B . n 
B 1 957 VAL 957 957 ?   ?   ?   B . n 
B 1 958 GLU 958 958 ?   ?   ?   B . n 
B 1 959 SER 959 959 ?   ?   ?   B . n 
B 1 960 PRO 960 960 ?   ?   ?   B . n 
B 1 961 GLY 961 961 ?   ?   ?   B . n 
B 1 962 LEU 962 962 ?   ?   ?   B . n 
B 1 963 GLU 963 963 ?   ?   ?   B . n 
B 1 964 GLU 964 964 ?   ?   ?   B . n 
B 1 965 GLU 965 965 ?   ?   ?   B . n 
B 1 966 LEU 966 966 ?   ?   ?   B . n 
B 1 967 ALA 967 967 ?   ?   ?   B . n 
B 1 968 ASP 968 968 ?   ?   ?   B . n 
B 1 969 ILE 969 969 ?   ?   ?   B . n 
B 1 970 LEU 970 970 ?   ?   ?   B . n 
B 1 971 GLN 971 971 ?   ?   ?   B . n 
B 1 972 GLY 972 972 ?   ?   ?   B . n 
B 1 973 PRO 973 973 ?   ?   ?   B . n 
B 1 974 SER 974 974 ?   ?   ?   B . n 
B 1 975 LEU 975 975 ?   ?   ?   B . n 
B 1 976 ARG 976 976 ?   ?   ?   B . n 
B 1 977 SER 977 977 ?   ?   ?   B . n 
B 1 978 THR 978 978 ?   ?   ?   B . n 
B 1 979 ASP 979 979 ?   ?   ?   B . n 
B 1 980 GLU 980 980 ?   ?   ?   B . n 
B 1 981 GLU 981 981 ?   ?   ?   B . n 
B 1 982 ASP 982 982 ?   ?   ?   B . n 
B 1 983 GLU 983 983 ?   ?   ?   B . n 
B 1 984 ASP 984 984 ?   ?   ?   B . n 
B 1 985 GLU 985 985 ?   ?   ?   B . n 
B 1 986 LEU 986 986 ?   ?   ?   B . n 
B 1 987 ILE 987 987 ?   ?   ?   B . n 
B 1 988 LEU 988 988 ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        SCN 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   SCN 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 SCN 1 1001 901 SCN SCN A . 
D 2 SCN 1 1002 902 SCN SCN A . 
E 2 SCN 1 1003 903 SCN SCN A . 
F 2 SCN 1 1004 904 SCN SCN A . 
G 2 SCN 1 1001 901 SCN SCN B . 
H 2 SCN 1 1002 902 SCN SCN B . 
I 2 SCN 1 1003 903 SCN SCN B . 
J 2 SCN 1 1004 904 SCN SCN B . 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8WXI 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8WXI 
_struct.title                        'human CLC-1 D136G delayed rectification' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8WXI 
_struct_keywords.text            'Channel, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
I N N 2 ? 
J N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    CLCN1_HUMAN 
_struct_ref.pdbx_db_accession          P35523 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQIYGHHKEQFSDREQDIGMPK
KTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIFLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQ
FLVWVTFPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIAS
ICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLA
VWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFV
IASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIP
CGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMM
VAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLV
DSKDSMILLGSVERSELQALLQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLS
GKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRARPTKKKTTQDSTDLVDNMSPE
EIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQL
RPPLASFRNTTSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESP
GLEEELADILQGPSLRSTDEEDEDELIL
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8WXI A 1 ? 988 ? P35523 1 ? 988 ? 1 988 
2 1 8WXI B 1 ? 988 ? P35523 1 ? 988 ? 1 988 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8WXI GLY A 136 ? UNP P35523 ASP 136 'engineered mutation' 136 1 
2 8WXI GLY B 136 ? UNP P35523 ASP 136 'engineered mutation' 136 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 115 ? MET A 153 ? GLY A 115 MET A 153 1 ? 39 
HELX_P HELX_P2  AA2 SER A 156 ? ILE A 182 ? SER A 156 ILE A 182 1 ? 27 
HELX_P HELX_P3  AA3 GLY A 190 ? ARG A 199 ? GLY A 190 ARG A 199 1 ? 10 
HELX_P HELX_P4  AA4 THR A 208 ? GLY A 224 ? THR A 208 GLY A 224 1 ? 17 
HELX_P HELX_P5  AA5 PRO A 234 ? SER A 251 ? PRO A 234 SER A 251 1 ? 18 
HELX_P HELX_P6  AA6 TYR A 263 ? GLY A 280 ? TYR A 263 GLY A 280 1 ? 18 
HELX_P HELX_P7  AA7 THR A 281 ? THR A 293 ? THR A 281 THR A 293 1 ? 13 
HELX_P HELX_P8  AA8 ALA A 298 ? ASN A 323 ? ALA A 298 ASN A 323 1 ? 26 
HELX_P HELX_P9  AA9 GLU A 347 ? HIS A 379 ? GLU A 347 HIS A 379 1 ? 33 
HELX_P HELX_P10 AB1 HIS A 379 ? HIS A 389 ? HIS A 379 HIS A 389 1 ? 11 
HELX_P HELX_P11 AB2 LEU A 391 ? THR A 405 ? LEU A 391 THR A 405 1 ? 15 
HELX_P HELX_P12 AB3 MET A 419 ? PHE A 428 ? MET A 419 PHE A 428 1 ? 10 
HELX_P HELX_P13 AB4 LEU A 443 ? VAL A 448 ? LEU A 443 VAL A 448 5 ? 6  
HELX_P HELX_P14 AB5 ASN A 455 ? THR A 475 ? ASN A 455 THR A 475 1 ? 21 
HELX_P HELX_P15 AB6 GLY A 483 ? PHE A 506 ? GLY A 483 PHE A 506 1 ? 24 
HELX_P HELX_P16 AB7 LEU A 520 ? HIS A 538 ? LEU A 520 HIS A 538 1 ? 19 
HELX_P HELX_P17 AB8 SER A 541 ? GLY A 551 ? SER A 541 GLY A 551 1 ? 11 
HELX_P HELX_P18 AB9 HIS A 555 ? SER A 572 ? HIS A 555 SER A 572 1 ? 18 
HELX_P HELX_P19 AC1 SER A 576 ? LYS A 585 ? SER A 576 LYS A 585 1 ? 10 
HELX_P HELX_P20 AC2 GLU B 116 ? MET B 153 ? GLU B 116 MET B 153 1 ? 38 
HELX_P HELX_P21 AC3 SER B 156 ? ILE B 182 ? SER B 156 ILE B 182 1 ? 27 
HELX_P HELX_P22 AC4 GLY B 190 ? ARG B 199 ? GLY B 190 ARG B 199 1 ? 10 
HELX_P HELX_P23 AC5 THR B 208 ? GLY B 224 ? THR B 208 GLY B 224 1 ? 17 
HELX_P HELX_P24 AC6 PRO B 234 ? SER B 251 ? PRO B 234 SER B 251 1 ? 18 
HELX_P HELX_P25 AC7 TYR B 263 ? GLY B 280 ? TYR B 263 GLY B 280 1 ? 18 
HELX_P HELX_P26 AC8 THR B 281 ? THR B 293 ? THR B 281 THR B 293 1 ? 13 
HELX_P HELX_P27 AC9 ALA B 298 ? ASN B 323 ? ALA B 298 ASN B 323 1 ? 26 
HELX_P HELX_P28 AD1 GLU B 347 ? HIS B 379 ? GLU B 347 HIS B 379 1 ? 33 
HELX_P HELX_P29 AD2 HIS B 379 ? HIS B 389 ? HIS B 379 HIS B 389 1 ? 11 
HELX_P HELX_P30 AD3 LEU B 391 ? THR B 405 ? LEU B 391 THR B 405 1 ? 15 
HELX_P HELX_P31 AD4 MET B 419 ? PHE B 428 ? MET B 419 PHE B 428 1 ? 10 
HELX_P HELX_P32 AD5 LEU B 443 ? VAL B 448 ? LEU B 443 VAL B 448 5 ? 6  
HELX_P HELX_P33 AD6 ASN B 455 ? THR B 475 ? ASN B 455 THR B 475 1 ? 21 
HELX_P HELX_P34 AD7 GLY B 483 ? PHE B 506 ? GLY B 483 PHE B 506 1 ? 24 
HELX_P HELX_P35 AD8 LEU B 520 ? HIS B 538 ? LEU B 520 HIS B 538 1 ? 19 
HELX_P HELX_P36 AD9 SER B 541 ? GLY B 551 ? SER B 541 GLY B 551 1 ? 11 
HELX_P HELX_P37 AE1 HIS B 555 ? SER B 572 ? HIS B 555 SER B 572 1 ? 18 
HELX_P HELX_P38 AE2 SER B 576 ? LYS B 585 ? SER B 576 LYS B 585 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 510 ? LEU A 511 ? ILE A 510 LEU A 511 
AA1 2 ILE A 516 ? TYR A 517 ? ILE A 516 TYR A 517 
AA2 1 ILE B 510 ? LEU B 511 ? ILE B 510 LEU B 511 
AA2 2 ILE B 516 ? TYR B 517 ? ILE B 516 TYR B 517 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 510 ? N ILE A 510 O TYR A 517 ? O TYR A 517 
AA2 1 2 N ILE B 510 ? N ILE B 510 O TYR B 517 ? O TYR B 517 
# 
_pdbx_entry_details.entry_id                   8WXI 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 CE1 A PHE 297 ? ? CE1 B PHE 297  ? ? 1.01 
2  1 O   A GLU 232 ? ? S   A SCN 1002 ? ? 1.08 
3  1 O   B GLU 232 ? ? S   B SCN 1002 ? ? 1.08 
4  1 CB  B SER 576 ? ? S   B SCN 1003 ? ? 1.17 
5  1 CB  A SER 576 ? ? S   A SCN 1003 ? ? 1.17 
6  1 CE1 A PHE 297 ? ? CZ  B PHE 297  ? ? 1.18 
7  1 CZ  A PHE 297 ? ? CE1 B PHE 297  ? ? 1.18 
8  1 OG  A SER 576 ? ? S   A SCN 1003 ? ? 1.29 
9  1 OG  B SER 576 ? ? S   B SCN 1003 ? ? 1.29 
10 1 CD1 A PHE 297 ? ? CE1 B PHE 297  ? ? 1.30 
11 1 CE1 A PHE 297 ? ? CD1 B PHE 297  ? ? 1.30 
12 1 OE2 A GLU 232 ? ? S   A SCN 1004 ? ? 1.33 
13 1 OE2 B GLU 232 ? ? S   B SCN 1004 ? ? 1.33 
14 1 CD1 A PHE 297 ? ? CZ  B PHE 297  ? ? 1.43 
15 1 CZ  A PHE 297 ? ? CD1 B PHE 297  ? ? 1.43 
16 1 C   A GLU 232 ? ? S   A SCN 1002 ? ? 1.50 
17 1 C   B GLU 232 ? ? S   B SCN 1002 ? ? 1.50 
18 1 CE2 B PHE 279 ? ? C   B SCN 1004 ? ? 1.54 
19 1 CE2 A PHE 279 ? ? C   A SCN 1004 ? ? 1.54 
20 1 CE1 A PHE 297 ? ? CE2 B PHE 297  ? ? 1.56 
21 1 CE2 A PHE 297 ? ? CE1 B PHE 297  ? ? 1.56 
22 1 CD  B GLU 232 ? ? S   B SCN 1004 ? ? 1.66 
23 1 CD  A GLU 232 ? ? S   A SCN 1004 ? ? 1.66 
24 1 CG  A PHE 297 ? ? CE1 B PHE 297  ? ? 1.67 
25 1 CE1 A PHE 297 ? ? CG  B PHE 297  ? ? 1.67 
26 1 CD2 A PHE 279 ? ? S   A SCN 1004 ? ? 1.72 
27 1 CD2 B PHE 279 ? ? S   B SCN 1004 ? ? 1.72 
28 1 CD2 A PHE 297 ? ? CE1 B PHE 297  ? ? 1.76 
29 1 CE1 A PHE 297 ? ? CD2 B PHE 297  ? ? 1.76 
30 1 OE2 A GLU 232 ? ? C   A SCN 1004 ? ? 1.84 
31 1 OE2 B GLU 232 ? ? C   B SCN 1004 ? ? 1.84 
32 1 OE1 B GLU 232 ? ? S   B SCN 1004 ? ? 1.89 
33 1 OE1 A GLU 232 ? ? S   A SCN 1004 ? ? 1.89 
34 1 CD1 A PHE 297 ? ? CD1 B PHE 297  ? ? 1.98 
35 1 CZ  A PHE 297 ? ? CZ  B PHE 297  ? ? 1.99 
36 1 CE2 A PHE 279 ? ? S   A SCN 1004 ? ? 2.03 
37 1 CE2 B PHE 279 ? ? S   B SCN 1004 ? ? 2.03 
38 1 OH  A TYR 302 ? ? CD1 B LEU 287  ? ? 2.05 
39 1 CD1 A LEU 287 ? ? OH  B TYR 302  ? ? 2.05 
40 1 CE2 A PHE 279 ? ? N   A SCN 1004 ? ? 2.12 
41 1 CE2 B PHE 279 ? ? N   B SCN 1004 ? ? 2.12 
42 1 N   A GLY 233 ? ? S   A SCN 1002 ? ? 2.13 
43 1 N   B GLY 233 ? ? S   B SCN 1002 ? ? 2.13 
44 1 CD1 A PHE 297 ? ? CE2 B PHE 297  ? ? 2.16 
45 1 CE2 A PHE 297 ? ? CD1 B PHE 297  ? ? 2.16 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 N  A VAL 236 ? ? CA A VAL 236 ? ? CB  A VAL 236 ? ? 127.11 111.50 15.61  2.20 N 
2 1 CA A VAL 236 ? ? CB A VAL 236 ? ? CG1 A VAL 236 ? ? 122.27 110.90 11.37  1.50 N 
3 1 N  A HIS 237 ? ? CA A HIS 237 ? ? C   A HIS 237 ? ? 89.45  111.00 -21.55 2.70 N 
4 1 N  B VAL 236 ? ? CA B VAL 236 ? ? CB  B VAL 236 ? ? 127.11 111.50 15.61  2.20 N 
5 1 CA B VAL 236 ? ? CB B VAL 236 ? ? CG1 B VAL 236 ? ? 122.27 110.90 11.37  1.50 N 
6 1 N  B HIS 237 ? ? CA B HIS 237 ? ? C   B HIS 237 ? ? 89.45  111.00 -21.55 2.70 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ILE A 182 ? ? -72.72  -74.16  
2  1 LEU A 207 ? ? -93.73  49.54   
3  1 PRO A 228 ? ? -68.01  81.58   
4  1 HIS A 237 ? ? 173.38  -54.92  
5  1 MET A 250 ? ? -82.79  -70.74  
6  1 CYS A 278 ? ? -52.68  -72.79  
7  1 THR A 293 ? ? -107.47 -78.85  
8  1 ASP A 325 ? ? 46.23   -119.17 
9  1 VAL A 327 ? ? -136.05 -147.29 
10 1 THR A 328 ? ? 52.90   -165.02 
11 1 PHE A 333 ? ? 62.92   -7.00   
12 1 PHE A 343 ? ? 70.47   128.50  
13 1 MET A 414 ? ? -146.01 17.97   
14 1 HIS A 436 ? ? -94.37  56.82   
15 1 PRO A 478 ? ? -75.82  47.47   
16 1 PHE A 512 ? ? -101.72 -69.30  
17 1 ASP A 513 ? ? -85.03  -85.60  
18 1 HIS A 555 ? ? -88.90  47.83   
19 1 LEU A 573 ? ? -117.03 -70.77  
20 1 ILE B 182 ? ? -72.72  -74.16  
21 1 LEU B 207 ? ? -93.73  49.54   
22 1 PRO B 228 ? ? -68.01  81.58   
23 1 HIS B 237 ? ? 173.38  -54.92  
24 1 MET B 250 ? ? -82.79  -70.74  
25 1 CYS B 278 ? ? -52.68  -72.79  
26 1 THR B 293 ? ? -107.47 -78.85  
27 1 ASP B 325 ? ? 46.23   -119.17 
28 1 VAL B 327 ? ? -136.05 -147.29 
29 1 THR B 328 ? ? 52.90   -165.02 
30 1 PHE B 333 ? ? 62.92   -7.00   
31 1 PHE B 343 ? ? 70.47   128.50  
32 1 MET B 414 ? ? -146.01 17.97   
33 1 HIS B 436 ? ? -94.37  56.82   
34 1 PRO B 478 ? ? -75.82  47.47   
35 1 PHE B 512 ? ? -101.72 -69.30  
36 1 ASP B 513 ? ? -85.03  -85.60  
37 1 HIS B 555 ? ? -88.90  47.83   
38 1 LEU B 573 ? ? -117.03 -70.77  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8WXI 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8WXI 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.57 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               38321 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'CLC-1 channel' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8WXI 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             1800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8WXI 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8WXI 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1    1 Y 1 A MET 1   ? A MET 1   
2    1 Y 1 A GLU 2   ? A GLU 2   
3    1 Y 1 A GLN 3   ? A GLN 3   
4    1 Y 1 A SER 4   ? A SER 4   
5    1 Y 1 A ARG 5   ? A ARG 5   
6    1 Y 1 A SER 6   ? A SER 6   
7    1 Y 1 A GLN 7   ? A GLN 7   
8    1 Y 1 A GLN 8   ? A GLN 8   
9    1 Y 1 A ARG 9   ? A ARG 9   
10   1 Y 1 A GLY 10  ? A GLY 10  
11   1 Y 1 A GLY 11  ? A GLY 11  
12   1 Y 1 A GLU 12  ? A GLU 12  
13   1 Y 1 A GLN 13  ? A GLN 13  
14   1 Y 1 A SER 14  ? A SER 14  
15   1 Y 1 A TRP 15  ? A TRP 15  
16   1 Y 1 A TRP 16  ? A TRP 16  
17   1 Y 1 A GLY 17  ? A GLY 17  
18   1 Y 1 A SER 18  ? A SER 18  
19   1 Y 1 A ASP 19  ? A ASP 19  
20   1 Y 1 A PRO 20  ? A PRO 20  
21   1 Y 1 A GLN 21  ? A GLN 21  
22   1 Y 1 A TYR 22  ? A TYR 22  
23   1 Y 1 A GLN 23  ? A GLN 23  
24   1 Y 1 A TYR 24  ? A TYR 24  
25   1 Y 1 A MET 25  ? A MET 25  
26   1 Y 1 A PRO 26  ? A PRO 26  
27   1 Y 1 A PHE 27  ? A PHE 27  
28   1 Y 1 A GLU 28  ? A GLU 28  
29   1 Y 1 A HIS 29  ? A HIS 29  
30   1 Y 1 A CYS 30  ? A CYS 30  
31   1 Y 1 A THR 31  ? A THR 31  
32   1 Y 1 A SER 32  ? A SER 32  
33   1 Y 1 A TYR 33  ? A TYR 33  
34   1 Y 1 A GLY 34  ? A GLY 34  
35   1 Y 1 A LEU 35  ? A LEU 35  
36   1 Y 1 A PRO 36  ? A PRO 36  
37   1 Y 1 A SER 37  ? A SER 37  
38   1 Y 1 A GLU 38  ? A GLU 38  
39   1 Y 1 A ASN 39  ? A ASN 39  
40   1 Y 1 A GLY 40  ? A GLY 40  
41   1 Y 1 A GLY 41  ? A GLY 41  
42   1 Y 1 A LEU 42  ? A LEU 42  
43   1 Y 1 A GLN 43  ? A GLN 43  
44   1 Y 1 A HIS 44  ? A HIS 44  
45   1 Y 1 A ARG 45  ? A ARG 45  
46   1 Y 1 A LEU 46  ? A LEU 46  
47   1 Y 1 A ARG 47  ? A ARG 47  
48   1 Y 1 A LYS 48  ? A LYS 48  
49   1 Y 1 A ASP 49  ? A ASP 49  
50   1 Y 1 A ALA 50  ? A ALA 50  
51   1 Y 1 A GLY 51  ? A GLY 51  
52   1 Y 1 A PRO 52  ? A PRO 52  
53   1 Y 1 A ARG 53  ? A ARG 53  
54   1 Y 1 A HIS 54  ? A HIS 54  
55   1 Y 1 A ASN 55  ? A ASN 55  
56   1 Y 1 A VAL 56  ? A VAL 56  
57   1 Y 1 A HIS 57  ? A HIS 57  
58   1 Y 1 A PRO 58  ? A PRO 58  
59   1 Y 1 A THR 59  ? A THR 59  
60   1 Y 1 A GLN 60  ? A GLN 60  
61   1 Y 1 A ILE 61  ? A ILE 61  
62   1 Y 1 A TYR 62  ? A TYR 62  
63   1 Y 1 A GLY 63  ? A GLY 63  
64   1 Y 1 A HIS 64  ? A HIS 64  
65   1 Y 1 A HIS 65  ? A HIS 65  
66   1 Y 1 A LYS 66  ? A LYS 66  
67   1 Y 1 A GLU 67  ? A GLU 67  
68   1 Y 1 A GLN 68  ? A GLN 68  
69   1 Y 1 A PHE 69  ? A PHE 69  
70   1 Y 1 A SER 70  ? A SER 70  
71   1 Y 1 A ASP 71  ? A ASP 71  
72   1 Y 1 A ARG 72  ? A ARG 72  
73   1 Y 1 A GLU 73  ? A GLU 73  
74   1 Y 1 A GLN 74  ? A GLN 74  
75   1 Y 1 A ASP 75  ? A ASP 75  
76   1 Y 1 A ILE 76  ? A ILE 76  
77   1 Y 1 A GLY 77  ? A GLY 77  
78   1 Y 1 A MET 78  ? A MET 78  
79   1 Y 1 A PRO 79  ? A PRO 79  
80   1 Y 1 A LYS 80  ? A LYS 80  
81   1 Y 1 A LYS 81  ? A LYS 81  
82   1 Y 1 A THR 82  ? A THR 82  
83   1 Y 1 A GLY 83  ? A GLY 83  
84   1 Y 1 A SER 84  ? A SER 84  
85   1 Y 1 A SER 85  ? A SER 85  
86   1 Y 1 A SER 86  ? A SER 86  
87   1 Y 1 A THR 87  ? A THR 87  
88   1 Y 1 A VAL 88  ? A VAL 88  
89   1 Y 1 A ASP 89  ? A ASP 89  
90   1 Y 1 A SER 90  ? A SER 90  
91   1 Y 1 A LYS 91  ? A LYS 91  
92   1 Y 1 A ASP 92  ? A ASP 92  
93   1 Y 1 A GLU 93  ? A GLU 93  
94   1 Y 1 A ASP 94  ? A ASP 94  
95   1 Y 1 A HIS 95  ? A HIS 95  
96   1 Y 1 A TYR 96  ? A TYR 96  
97   1 Y 1 A SER 97  ? A SER 97  
98   1 Y 1 A LYS 98  ? A LYS 98  
99   1 Y 1 A CYS 99  ? A CYS 99  
100  1 Y 1 A GLN 100 ? A GLN 100 
101  1 Y 1 A ASP 101 ? A ASP 101 
102  1 Y 1 A CYS 102 ? A CYS 102 
103  1 Y 1 A ILE 103 ? A ILE 103 
104  1 Y 1 A HIS 104 ? A HIS 104 
105  1 Y 1 A ARG 105 ? A ARG 105 
106  1 Y 1 A LEU 106 ? A LEU 106 
107  1 Y 1 A GLY 107 ? A GLY 107 
108  1 Y 1 A GLN 108 ? A GLN 108 
109  1 Y 1 A VAL 109 ? A VAL 109 
110  1 Y 1 A VAL 110 ? A VAL 110 
111  1 Y 1 A ARG 111 ? A ARG 111 
112  1 Y 1 A ARG 112 ? A ARG 112 
113  1 Y 1 A LYS 113 ? A LYS 113 
114  1 Y 1 A LEU 114 ? A LEU 114 
115  1 Y 1 A CYS 254 ? A CYS 254 
116  1 Y 1 A GLY 255 ? A GLY 255 
117  1 Y 1 A VAL 256 ? A VAL 256 
118  1 Y 1 A TYR 257 ? A TYR 257 
119  1 Y 1 A GLU 258 ? A GLU 258 
120  1 Y 1 A GLN 259 ? A GLN 259 
121  1 Y 1 A PRO 260 ? A PRO 260 
122  1 Y 1 A TYR 261 ? A TYR 261 
123  1 Y 1 A LEU 590 ? A LEU 590 
124  1 Y 1 A PRO 591 ? A PRO 591 
125  1 Y 1 A ASP 592 ? A ASP 592 
126  1 Y 1 A LEU 593 ? A LEU 593 
127  1 Y 1 A GLY 594 ? A GLY 594 
128  1 Y 1 A TRP 595 ? A TRP 595 
129  1 Y 1 A ASN 596 ? A ASN 596 
130  1 Y 1 A GLN 597 ? A GLN 597 
131  1 Y 1 A LEU 598 ? A LEU 598 
132  1 Y 1 A SER 599 ? A SER 599 
133  1 Y 1 A LYS 600 ? A LYS 600 
134  1 Y 1 A TYR 601 ? A TYR 601 
135  1 Y 1 A THR 602 ? A THR 602 
136  1 Y 1 A ILE 603 ? A ILE 603 
137  1 Y 1 A PHE 604 ? A PHE 604 
138  1 Y 1 A VAL 605 ? A VAL 605 
139  1 Y 1 A GLU 606 ? A GLU 606 
140  1 Y 1 A ASP 607 ? A ASP 607 
141  1 Y 1 A ILE 608 ? A ILE 608 
142  1 Y 1 A MET 609 ? A MET 609 
143  1 Y 1 A VAL 610 ? A VAL 610 
144  1 Y 1 A ARG 611 ? A ARG 611 
145  1 Y 1 A ASP 612 ? A ASP 612 
146  1 Y 1 A VAL 613 ? A VAL 613 
147  1 Y 1 A LYS 614 ? A LYS 614 
148  1 Y 1 A PHE 615 ? A PHE 615 
149  1 Y 1 A VAL 616 ? A VAL 616 
150  1 Y 1 A SER 617 ? A SER 617 
151  1 Y 1 A ALA 618 ? A ALA 618 
152  1 Y 1 A SER 619 ? A SER 619 
153  1 Y 1 A TYR 620 ? A TYR 620 
154  1 Y 1 A THR 621 ? A THR 621 
155  1 Y 1 A TYR 622 ? A TYR 622 
156  1 Y 1 A GLY 623 ? A GLY 623 
157  1 Y 1 A GLU 624 ? A GLU 624 
158  1 Y 1 A LEU 625 ? A LEU 625 
159  1 Y 1 A ARG 626 ? A ARG 626 
160  1 Y 1 A THR 627 ? A THR 627 
161  1 Y 1 A LEU 628 ? A LEU 628 
162  1 Y 1 A LEU 629 ? A LEU 629 
163  1 Y 1 A GLN 630 ? A GLN 630 
164  1 Y 1 A THR 631 ? A THR 631 
165  1 Y 1 A THR 632 ? A THR 632 
166  1 Y 1 A THR 633 ? A THR 633 
167  1 Y 1 A VAL 634 ? A VAL 634 
168  1 Y 1 A LYS 635 ? A LYS 635 
169  1 Y 1 A THR 636 ? A THR 636 
170  1 Y 1 A LEU 637 ? A LEU 637 
171  1 Y 1 A PRO 638 ? A PRO 638 
172  1 Y 1 A LEU 639 ? A LEU 639 
173  1 Y 1 A VAL 640 ? A VAL 640 
174  1 Y 1 A ASP 641 ? A ASP 641 
175  1 Y 1 A SER 642 ? A SER 642 
176  1 Y 1 A LYS 643 ? A LYS 643 
177  1 Y 1 A ASP 644 ? A ASP 644 
178  1 Y 1 A SER 645 ? A SER 645 
179  1 Y 1 A MET 646 ? A MET 646 
180  1 Y 1 A ILE 647 ? A ILE 647 
181  1 Y 1 A LEU 648 ? A LEU 648 
182  1 Y 1 A LEU 649 ? A LEU 649 
183  1 Y 1 A GLY 650 ? A GLY 650 
184  1 Y 1 A SER 651 ? A SER 651 
185  1 Y 1 A VAL 652 ? A VAL 652 
186  1 Y 1 A GLU 653 ? A GLU 653 
187  1 Y 1 A ARG 654 ? A ARG 654 
188  1 Y 1 A SER 655 ? A SER 655 
189  1 Y 1 A GLU 656 ? A GLU 656 
190  1 Y 1 A LEU 657 ? A LEU 657 
191  1 Y 1 A GLN 658 ? A GLN 658 
192  1 Y 1 A ALA 659 ? A ALA 659 
193  1 Y 1 A LEU 660 ? A LEU 660 
194  1 Y 1 A LEU 661 ? A LEU 661 
195  1 Y 1 A GLN 662 ? A GLN 662 
196  1 Y 1 A ARG 663 ? A ARG 663 
197  1 Y 1 A HIS 664 ? A HIS 664 
198  1 Y 1 A LEU 665 ? A LEU 665 
199  1 Y 1 A CYS 666 ? A CYS 666 
200  1 Y 1 A PRO 667 ? A PRO 667 
201  1 Y 1 A GLU 668 ? A GLU 668 
202  1 Y 1 A ARG 669 ? A ARG 669 
203  1 Y 1 A ARG 670 ? A ARG 670 
204  1 Y 1 A LEU 671 ? A LEU 671 
205  1 Y 1 A ARG 672 ? A ARG 672 
206  1 Y 1 A ALA 673 ? A ALA 673 
207  1 Y 1 A ALA 674 ? A ALA 674 
208  1 Y 1 A GLN 675 ? A GLN 675 
209  1 Y 1 A GLU 676 ? A GLU 676 
210  1 Y 1 A MET 677 ? A MET 677 
211  1 Y 1 A ALA 678 ? A ALA 678 
212  1 Y 1 A ARG 679 ? A ARG 679 
213  1 Y 1 A LYS 680 ? A LYS 680 
214  1 Y 1 A LEU 681 ? A LEU 681 
215  1 Y 1 A SER 682 ? A SER 682 
216  1 Y 1 A GLU 683 ? A GLU 683 
217  1 Y 1 A LEU 684 ? A LEU 684 
218  1 Y 1 A PRO 685 ? A PRO 685 
219  1 Y 1 A TYR 686 ? A TYR 686 
220  1 Y 1 A ASP 687 ? A ASP 687 
221  1 Y 1 A GLY 688 ? A GLY 688 
222  1 Y 1 A LYS 689 ? A LYS 689 
223  1 Y 1 A ALA 690 ? A ALA 690 
224  1 Y 1 A ARG 691 ? A ARG 691 
225  1 Y 1 A LEU 692 ? A LEU 692 
226  1 Y 1 A ALA 693 ? A ALA 693 
227  1 Y 1 A GLY 694 ? A GLY 694 
228  1 Y 1 A GLU 695 ? A GLU 695 
229  1 Y 1 A GLY 696 ? A GLY 696 
230  1 Y 1 A LEU 697 ? A LEU 697 
231  1 Y 1 A PRO 698 ? A PRO 698 
232  1 Y 1 A GLY 699 ? A GLY 699 
233  1 Y 1 A ALA 700 ? A ALA 700 
234  1 Y 1 A PRO 701 ? A PRO 701 
235  1 Y 1 A PRO 702 ? A PRO 702 
236  1 Y 1 A GLY 703 ? A GLY 703 
237  1 Y 1 A ARG 704 ? A ARG 704 
238  1 Y 1 A PRO 705 ? A PRO 705 
239  1 Y 1 A GLU 706 ? A GLU 706 
240  1 Y 1 A SER 707 ? A SER 707 
241  1 Y 1 A PHE 708 ? A PHE 708 
242  1 Y 1 A ALA 709 ? A ALA 709 
243  1 Y 1 A PHE 710 ? A PHE 710 
244  1 Y 1 A VAL 711 ? A VAL 711 
245  1 Y 1 A ASP 712 ? A ASP 712 
246  1 Y 1 A GLU 713 ? A GLU 713 
247  1 Y 1 A ASP 714 ? A ASP 714 
248  1 Y 1 A GLU 715 ? A GLU 715 
249  1 Y 1 A ASP 716 ? A ASP 716 
250  1 Y 1 A GLU 717 ? A GLU 717 
251  1 Y 1 A ASP 718 ? A ASP 718 
252  1 Y 1 A LEU 719 ? A LEU 719 
253  1 Y 1 A SER 720 ? A SER 720 
254  1 Y 1 A GLY 721 ? A GLY 721 
255  1 Y 1 A LYS 722 ? A LYS 722 
256  1 Y 1 A SER 723 ? A SER 723 
257  1 Y 1 A GLU 724 ? A GLU 724 
258  1 Y 1 A LEU 725 ? A LEU 725 
259  1 Y 1 A PRO 726 ? A PRO 726 
260  1 Y 1 A PRO 727 ? A PRO 727 
261  1 Y 1 A SER 728 ? A SER 728 
262  1 Y 1 A LEU 729 ? A LEU 729 
263  1 Y 1 A ALA 730 ? A ALA 730 
264  1 Y 1 A LEU 731 ? A LEU 731 
265  1 Y 1 A HIS 732 ? A HIS 732 
266  1 Y 1 A PRO 733 ? A PRO 733 
267  1 Y 1 A SER 734 ? A SER 734 
268  1 Y 1 A THR 735 ? A THR 735 
269  1 Y 1 A THR 736 ? A THR 736 
270  1 Y 1 A ALA 737 ? A ALA 737 
271  1 Y 1 A PRO 738 ? A PRO 738 
272  1 Y 1 A LEU 739 ? A LEU 739 
273  1 Y 1 A SER 740 ? A SER 740 
274  1 Y 1 A PRO 741 ? A PRO 741 
275  1 Y 1 A GLU 742 ? A GLU 742 
276  1 Y 1 A GLU 743 ? A GLU 743 
277  1 Y 1 A PRO 744 ? A PRO 744 
278  1 Y 1 A ASN 745 ? A ASN 745 
279  1 Y 1 A GLY 746 ? A GLY 746 
280  1 Y 1 A PRO 747 ? A PRO 747 
281  1 Y 1 A LEU 748 ? A LEU 748 
282  1 Y 1 A PRO 749 ? A PRO 749 
283  1 Y 1 A GLY 750 ? A GLY 750 
284  1 Y 1 A HIS 751 ? A HIS 751 
285  1 Y 1 A LYS 752 ? A LYS 752 
286  1 Y 1 A GLN 753 ? A GLN 753 
287  1 Y 1 A GLN 754 ? A GLN 754 
288  1 Y 1 A PRO 755 ? A PRO 755 
289  1 Y 1 A GLU 756 ? A GLU 756 
290  1 Y 1 A ALA 757 ? A ALA 757 
291  1 Y 1 A PRO 758 ? A PRO 758 
292  1 Y 1 A GLU 759 ? A GLU 759 
293  1 Y 1 A PRO 760 ? A PRO 760 
294  1 Y 1 A ALA 761 ? A ALA 761 
295  1 Y 1 A GLY 762 ? A GLY 762 
296  1 Y 1 A GLN 763 ? A GLN 763 
297  1 Y 1 A ARG 764 ? A ARG 764 
298  1 Y 1 A PRO 765 ? A PRO 765 
299  1 Y 1 A SER 766 ? A SER 766 
300  1 Y 1 A ILE 767 ? A ILE 767 
301  1 Y 1 A PHE 768 ? A PHE 768 
302  1 Y 1 A GLN 769 ? A GLN 769 
303  1 Y 1 A SER 770 ? A SER 770 
304  1 Y 1 A LEU 771 ? A LEU 771 
305  1 Y 1 A LEU 772 ? A LEU 772 
306  1 Y 1 A HIS 773 ? A HIS 773 
307  1 Y 1 A CYS 774 ? A CYS 774 
308  1 Y 1 A LEU 775 ? A LEU 775 
309  1 Y 1 A LEU 776 ? A LEU 776 
310  1 Y 1 A GLY 777 ? A GLY 777 
311  1 Y 1 A ARG 778 ? A ARG 778 
312  1 Y 1 A ALA 779 ? A ALA 779 
313  1 Y 1 A ARG 780 ? A ARG 780 
314  1 Y 1 A PRO 781 ? A PRO 781 
315  1 Y 1 A THR 782 ? A THR 782 
316  1 Y 1 A LYS 783 ? A LYS 783 
317  1 Y 1 A LYS 784 ? A LYS 784 
318  1 Y 1 A LYS 785 ? A LYS 785 
319  1 Y 1 A THR 786 ? A THR 786 
320  1 Y 1 A THR 787 ? A THR 787 
321  1 Y 1 A GLN 788 ? A GLN 788 
322  1 Y 1 A ASP 789 ? A ASP 789 
323  1 Y 1 A SER 790 ? A SER 790 
324  1 Y 1 A THR 791 ? A THR 791 
325  1 Y 1 A ASP 792 ? A ASP 792 
326  1 Y 1 A LEU 793 ? A LEU 793 
327  1 Y 1 A VAL 794 ? A VAL 794 
328  1 Y 1 A ASP 795 ? A ASP 795 
329  1 Y 1 A ASN 796 ? A ASN 796 
330  1 Y 1 A MET 797 ? A MET 797 
331  1 Y 1 A SER 798 ? A SER 798 
332  1 Y 1 A PRO 799 ? A PRO 799 
333  1 Y 1 A GLU 800 ? A GLU 800 
334  1 Y 1 A GLU 801 ? A GLU 801 
335  1 Y 1 A ILE 802 ? A ILE 802 
336  1 Y 1 A GLU 803 ? A GLU 803 
337  1 Y 1 A ALA 804 ? A ALA 804 
338  1 Y 1 A TRP 805 ? A TRP 805 
339  1 Y 1 A GLU 806 ? A GLU 806 
340  1 Y 1 A GLN 807 ? A GLN 807 
341  1 Y 1 A GLU 808 ? A GLU 808 
342  1 Y 1 A GLN 809 ? A GLN 809 
343  1 Y 1 A LEU 810 ? A LEU 810 
344  1 Y 1 A SER 811 ? A SER 811 
345  1 Y 1 A GLN 812 ? A GLN 812 
346  1 Y 1 A PRO 813 ? A PRO 813 
347  1 Y 1 A VAL 814 ? A VAL 814 
348  1 Y 1 A CYS 815 ? A CYS 815 
349  1 Y 1 A PHE 816 ? A PHE 816 
350  1 Y 1 A ASP 817 ? A ASP 817 
351  1 Y 1 A SER 818 ? A SER 818 
352  1 Y 1 A CYS 819 ? A CYS 819 
353  1 Y 1 A CYS 820 ? A CYS 820 
354  1 Y 1 A ILE 821 ? A ILE 821 
355  1 Y 1 A ASP 822 ? A ASP 822 
356  1 Y 1 A GLN 823 ? A GLN 823 
357  1 Y 1 A SER 824 ? A SER 824 
358  1 Y 1 A PRO 825 ? A PRO 825 
359  1 Y 1 A PHE 826 ? A PHE 826 
360  1 Y 1 A GLN 827 ? A GLN 827 
361  1 Y 1 A LEU 828 ? A LEU 828 
362  1 Y 1 A VAL 829 ? A VAL 829 
363  1 Y 1 A GLU 830 ? A GLU 830 
364  1 Y 1 A GLN 831 ? A GLN 831 
365  1 Y 1 A THR 832 ? A THR 832 
366  1 Y 1 A THR 833 ? A THR 833 
367  1 Y 1 A LEU 834 ? A LEU 834 
368  1 Y 1 A HIS 835 ? A HIS 835 
369  1 Y 1 A LYS 836 ? A LYS 836 
370  1 Y 1 A THR 837 ? A THR 837 
371  1 Y 1 A HIS 838 ? A HIS 838 
372  1 Y 1 A THR 839 ? A THR 839 
373  1 Y 1 A LEU 840 ? A LEU 840 
374  1 Y 1 A PHE 841 ? A PHE 841 
375  1 Y 1 A SER 842 ? A SER 842 
376  1 Y 1 A LEU 843 ? A LEU 843 
377  1 Y 1 A LEU 844 ? A LEU 844 
378  1 Y 1 A GLY 845 ? A GLY 845 
379  1 Y 1 A LEU 846 ? A LEU 846 
380  1 Y 1 A HIS 847 ? A HIS 847 
381  1 Y 1 A LEU 848 ? A LEU 848 
382  1 Y 1 A ALA 849 ? A ALA 849 
383  1 Y 1 A TYR 850 ? A TYR 850 
384  1 Y 1 A VAL 851 ? A VAL 851 
385  1 Y 1 A THR 852 ? A THR 852 
386  1 Y 1 A SER 853 ? A SER 853 
387  1 Y 1 A MET 854 ? A MET 854 
388  1 Y 1 A GLY 855 ? A GLY 855 
389  1 Y 1 A LYS 856 ? A LYS 856 
390  1 Y 1 A LEU 857 ? A LEU 857 
391  1 Y 1 A ARG 858 ? A ARG 858 
392  1 Y 1 A GLY 859 ? A GLY 859 
393  1 Y 1 A VAL 860 ? A VAL 860 
394  1 Y 1 A LEU 861 ? A LEU 861 
395  1 Y 1 A ALA 862 ? A ALA 862 
396  1 Y 1 A LEU 863 ? A LEU 863 
397  1 Y 1 A GLU 864 ? A GLU 864 
398  1 Y 1 A GLU 865 ? A GLU 865 
399  1 Y 1 A LEU 866 ? A LEU 866 
400  1 Y 1 A GLN 867 ? A GLN 867 
401  1 Y 1 A LYS 868 ? A LYS 868 
402  1 Y 1 A ALA 869 ? A ALA 869 
403  1 Y 1 A ILE 870 ? A ILE 870 
404  1 Y 1 A GLU 871 ? A GLU 871 
405  1 Y 1 A GLY 872 ? A GLY 872 
406  1 Y 1 A HIS 873 ? A HIS 873 
407  1 Y 1 A THR 874 ? A THR 874 
408  1 Y 1 A LYS 875 ? A LYS 875 
409  1 Y 1 A SER 876 ? A SER 876 
410  1 Y 1 A GLY 877 ? A GLY 877 
411  1 Y 1 A VAL 878 ? A VAL 878 
412  1 Y 1 A GLN 879 ? A GLN 879 
413  1 Y 1 A LEU 880 ? A LEU 880 
414  1 Y 1 A ARG 881 ? A ARG 881 
415  1 Y 1 A PRO 882 ? A PRO 882 
416  1 Y 1 A PRO 883 ? A PRO 883 
417  1 Y 1 A LEU 884 ? A LEU 884 
418  1 Y 1 A ALA 885 ? A ALA 885 
419  1 Y 1 A SER 886 ? A SER 886 
420  1 Y 1 A PHE 887 ? A PHE 887 
421  1 Y 1 A ARG 888 ? A ARG 888 
422  1 Y 1 A ASN 889 ? A ASN 889 
423  1 Y 1 A THR 890 ? A THR 890 
424  1 Y 1 A THR 891 ? A THR 891 
425  1 Y 1 A SER 892 ? A SER 892 
426  1 Y 1 A THR 893 ? A THR 893 
427  1 Y 1 A ARG 894 ? A ARG 894 
428  1 Y 1 A LYS 895 ? A LYS 895 
429  1 Y 1 A SER 896 ? A SER 896 
430  1 Y 1 A THR 897 ? A THR 897 
431  1 Y 1 A GLY 898 ? A GLY 898 
432  1 Y 1 A ALA 899 ? A ALA 899 
433  1 Y 1 A PRO 900 ? A PRO 900 
434  1 Y 1 A PRO 901 ? A PRO 901 
435  1 Y 1 A SER 902 ? A SER 902 
436  1 Y 1 A SER 903 ? A SER 903 
437  1 Y 1 A ALA 904 ? A ALA 904 
438  1 Y 1 A GLU 905 ? A GLU 905 
439  1 Y 1 A ASN 906 ? A ASN 906 
440  1 Y 1 A TRP 907 ? A TRP 907 
441  1 Y 1 A ASN 908 ? A ASN 908 
442  1 Y 1 A LEU 909 ? A LEU 909 
443  1 Y 1 A PRO 910 ? A PRO 910 
444  1 Y 1 A GLU 911 ? A GLU 911 
445  1 Y 1 A ASP 912 ? A ASP 912 
446  1 Y 1 A ARG 913 ? A ARG 913 
447  1 Y 1 A PRO 914 ? A PRO 914 
448  1 Y 1 A GLY 915 ? A GLY 915 
449  1 Y 1 A ALA 916 ? A ALA 916 
450  1 Y 1 A THR 917 ? A THR 917 
451  1 Y 1 A GLY 918 ? A GLY 918 
452  1 Y 1 A THR 919 ? A THR 919 
453  1 Y 1 A GLY 920 ? A GLY 920 
454  1 Y 1 A ASP 921 ? A ASP 921 
455  1 Y 1 A VAL 922 ? A VAL 922 
456  1 Y 1 A ILE 923 ? A ILE 923 
457  1 Y 1 A ALA 924 ? A ALA 924 
458  1 Y 1 A ALA 925 ? A ALA 925 
459  1 Y 1 A SER 926 ? A SER 926 
460  1 Y 1 A PRO 927 ? A PRO 927 
461  1 Y 1 A GLU 928 ? A GLU 928 
462  1 Y 1 A THR 929 ? A THR 929 
463  1 Y 1 A PRO 930 ? A PRO 930 
464  1 Y 1 A VAL 931 ? A VAL 931 
465  1 Y 1 A PRO 932 ? A PRO 932 
466  1 Y 1 A SER 933 ? A SER 933 
467  1 Y 1 A PRO 934 ? A PRO 934 
468  1 Y 1 A SER 935 ? A SER 935 
469  1 Y 1 A PRO 936 ? A PRO 936 
470  1 Y 1 A GLU 937 ? A GLU 937 
471  1 Y 1 A PRO 938 ? A PRO 938 
472  1 Y 1 A PRO 939 ? A PRO 939 
473  1 Y 1 A LEU 940 ? A LEU 940 
474  1 Y 1 A SER 941 ? A SER 941 
475  1 Y 1 A LEU 942 ? A LEU 942 
476  1 Y 1 A ALA 943 ? A ALA 943 
477  1 Y 1 A PRO 944 ? A PRO 944 
478  1 Y 1 A GLY 945 ? A GLY 945 
479  1 Y 1 A LYS 946 ? A LYS 946 
480  1 Y 1 A VAL 947 ? A VAL 947 
481  1 Y 1 A GLU 948 ? A GLU 948 
482  1 Y 1 A GLY 949 ? A GLY 949 
483  1 Y 1 A GLU 950 ? A GLU 950 
484  1 Y 1 A LEU 951 ? A LEU 951 
485  1 Y 1 A GLU 952 ? A GLU 952 
486  1 Y 1 A GLU 953 ? A GLU 953 
487  1 Y 1 A LEU 954 ? A LEU 954 
488  1 Y 1 A GLU 955 ? A GLU 955 
489  1 Y 1 A LEU 956 ? A LEU 956 
490  1 Y 1 A VAL 957 ? A VAL 957 
491  1 Y 1 A GLU 958 ? A GLU 958 
492  1 Y 1 A SER 959 ? A SER 959 
493  1 Y 1 A PRO 960 ? A PRO 960 
494  1 Y 1 A GLY 961 ? A GLY 961 
495  1 Y 1 A LEU 962 ? A LEU 962 
496  1 Y 1 A GLU 963 ? A GLU 963 
497  1 Y 1 A GLU 964 ? A GLU 964 
498  1 Y 1 A GLU 965 ? A GLU 965 
499  1 Y 1 A LEU 966 ? A LEU 966 
500  1 Y 1 A ALA 967 ? A ALA 967 
501  1 Y 1 A ASP 968 ? A ASP 968 
502  1 Y 1 A ILE 969 ? A ILE 969 
503  1 Y 1 A LEU 970 ? A LEU 970 
504  1 Y 1 A GLN 971 ? A GLN 971 
505  1 Y 1 A GLY 972 ? A GLY 972 
506  1 Y 1 A PRO 973 ? A PRO 973 
507  1 Y 1 A SER 974 ? A SER 974 
508  1 Y 1 A LEU 975 ? A LEU 975 
509  1 Y 1 A ARG 976 ? A ARG 976 
510  1 Y 1 A SER 977 ? A SER 977 
511  1 Y 1 A THR 978 ? A THR 978 
512  1 Y 1 A ASP 979 ? A ASP 979 
513  1 Y 1 A GLU 980 ? A GLU 980 
514  1 Y 1 A GLU 981 ? A GLU 981 
515  1 Y 1 A ASP 982 ? A ASP 982 
516  1 Y 1 A GLU 983 ? A GLU 983 
517  1 Y 1 A ASP 984 ? A ASP 984 
518  1 Y 1 A GLU 985 ? A GLU 985 
519  1 Y 1 A LEU 986 ? A LEU 986 
520  1 Y 1 A ILE 987 ? A ILE 987 
521  1 Y 1 A LEU 988 ? A LEU 988 
522  1 Y 1 B MET 1   ? B MET 1   
523  1 Y 1 B GLU 2   ? B GLU 2   
524  1 Y 1 B GLN 3   ? B GLN 3   
525  1 Y 1 B SER 4   ? B SER 4   
526  1 Y 1 B ARG 5   ? B ARG 5   
527  1 Y 1 B SER 6   ? B SER 6   
528  1 Y 1 B GLN 7   ? B GLN 7   
529  1 Y 1 B GLN 8   ? B GLN 8   
530  1 Y 1 B ARG 9   ? B ARG 9   
531  1 Y 1 B GLY 10  ? B GLY 10  
532  1 Y 1 B GLY 11  ? B GLY 11  
533  1 Y 1 B GLU 12  ? B GLU 12  
534  1 Y 1 B GLN 13  ? B GLN 13  
535  1 Y 1 B SER 14  ? B SER 14  
536  1 Y 1 B TRP 15  ? B TRP 15  
537  1 Y 1 B TRP 16  ? B TRP 16  
538  1 Y 1 B GLY 17  ? B GLY 17  
539  1 Y 1 B SER 18  ? B SER 18  
540  1 Y 1 B ASP 19  ? B ASP 19  
541  1 Y 1 B PRO 20  ? B PRO 20  
542  1 Y 1 B GLN 21  ? B GLN 21  
543  1 Y 1 B TYR 22  ? B TYR 22  
544  1 Y 1 B GLN 23  ? B GLN 23  
545  1 Y 1 B TYR 24  ? B TYR 24  
546  1 Y 1 B MET 25  ? B MET 25  
547  1 Y 1 B PRO 26  ? B PRO 26  
548  1 Y 1 B PHE 27  ? B PHE 27  
549  1 Y 1 B GLU 28  ? B GLU 28  
550  1 Y 1 B HIS 29  ? B HIS 29  
551  1 Y 1 B CYS 30  ? B CYS 30  
552  1 Y 1 B THR 31  ? B THR 31  
553  1 Y 1 B SER 32  ? B SER 32  
554  1 Y 1 B TYR 33  ? B TYR 33  
555  1 Y 1 B GLY 34  ? B GLY 34  
556  1 Y 1 B LEU 35  ? B LEU 35  
557  1 Y 1 B PRO 36  ? B PRO 36  
558  1 Y 1 B SER 37  ? B SER 37  
559  1 Y 1 B GLU 38  ? B GLU 38  
560  1 Y 1 B ASN 39  ? B ASN 39  
561  1 Y 1 B GLY 40  ? B GLY 40  
562  1 Y 1 B GLY 41  ? B GLY 41  
563  1 Y 1 B LEU 42  ? B LEU 42  
564  1 Y 1 B GLN 43  ? B GLN 43  
565  1 Y 1 B HIS 44  ? B HIS 44  
566  1 Y 1 B ARG 45  ? B ARG 45  
567  1 Y 1 B LEU 46  ? B LEU 46  
568  1 Y 1 B ARG 47  ? B ARG 47  
569  1 Y 1 B LYS 48  ? B LYS 48  
570  1 Y 1 B ASP 49  ? B ASP 49  
571  1 Y 1 B ALA 50  ? B ALA 50  
572  1 Y 1 B GLY 51  ? B GLY 51  
573  1 Y 1 B PRO 52  ? B PRO 52  
574  1 Y 1 B ARG 53  ? B ARG 53  
575  1 Y 1 B HIS 54  ? B HIS 54  
576  1 Y 1 B ASN 55  ? B ASN 55  
577  1 Y 1 B VAL 56  ? B VAL 56  
578  1 Y 1 B HIS 57  ? B HIS 57  
579  1 Y 1 B PRO 58  ? B PRO 58  
580  1 Y 1 B THR 59  ? B THR 59  
581  1 Y 1 B GLN 60  ? B GLN 60  
582  1 Y 1 B ILE 61  ? B ILE 61  
583  1 Y 1 B TYR 62  ? B TYR 62  
584  1 Y 1 B GLY 63  ? B GLY 63  
585  1 Y 1 B HIS 64  ? B HIS 64  
586  1 Y 1 B HIS 65  ? B HIS 65  
587  1 Y 1 B LYS 66  ? B LYS 66  
588  1 Y 1 B GLU 67  ? B GLU 67  
589  1 Y 1 B GLN 68  ? B GLN 68  
590  1 Y 1 B PHE 69  ? B PHE 69  
591  1 Y 1 B SER 70  ? B SER 70  
592  1 Y 1 B ASP 71  ? B ASP 71  
593  1 Y 1 B ARG 72  ? B ARG 72  
594  1 Y 1 B GLU 73  ? B GLU 73  
595  1 Y 1 B GLN 74  ? B GLN 74  
596  1 Y 1 B ASP 75  ? B ASP 75  
597  1 Y 1 B ILE 76  ? B ILE 76  
598  1 Y 1 B GLY 77  ? B GLY 77  
599  1 Y 1 B MET 78  ? B MET 78  
600  1 Y 1 B PRO 79  ? B PRO 79  
601  1 Y 1 B LYS 80  ? B LYS 80  
602  1 Y 1 B LYS 81  ? B LYS 81  
603  1 Y 1 B THR 82  ? B THR 82  
604  1 Y 1 B GLY 83  ? B GLY 83  
605  1 Y 1 B SER 84  ? B SER 84  
606  1 Y 1 B SER 85  ? B SER 85  
607  1 Y 1 B SER 86  ? B SER 86  
608  1 Y 1 B THR 87  ? B THR 87  
609  1 Y 1 B VAL 88  ? B VAL 88  
610  1 Y 1 B ASP 89  ? B ASP 89  
611  1 Y 1 B SER 90  ? B SER 90  
612  1 Y 1 B LYS 91  ? B LYS 91  
613  1 Y 1 B ASP 92  ? B ASP 92  
614  1 Y 1 B GLU 93  ? B GLU 93  
615  1 Y 1 B ASP 94  ? B ASP 94  
616  1 Y 1 B HIS 95  ? B HIS 95  
617  1 Y 1 B TYR 96  ? B TYR 96  
618  1 Y 1 B SER 97  ? B SER 97  
619  1 Y 1 B LYS 98  ? B LYS 98  
620  1 Y 1 B CYS 99  ? B CYS 99  
621  1 Y 1 B GLN 100 ? B GLN 100 
622  1 Y 1 B ASP 101 ? B ASP 101 
623  1 Y 1 B CYS 102 ? B CYS 102 
624  1 Y 1 B ILE 103 ? B ILE 103 
625  1 Y 1 B HIS 104 ? B HIS 104 
626  1 Y 1 B ARG 105 ? B ARG 105 
627  1 Y 1 B LEU 106 ? B LEU 106 
628  1 Y 1 B GLY 107 ? B GLY 107 
629  1 Y 1 B GLN 108 ? B GLN 108 
630  1 Y 1 B VAL 109 ? B VAL 109 
631  1 Y 1 B VAL 110 ? B VAL 110 
632  1 Y 1 B ARG 111 ? B ARG 111 
633  1 Y 1 B ARG 112 ? B ARG 112 
634  1 Y 1 B LYS 113 ? B LYS 113 
635  1 Y 1 B LEU 114 ? B LEU 114 
636  1 Y 1 B CYS 254 ? B CYS 254 
637  1 Y 1 B GLY 255 ? B GLY 255 
638  1 Y 1 B VAL 256 ? B VAL 256 
639  1 Y 1 B TYR 257 ? B TYR 257 
640  1 Y 1 B GLU 258 ? B GLU 258 
641  1 Y 1 B GLN 259 ? B GLN 259 
642  1 Y 1 B PRO 260 ? B PRO 260 
643  1 Y 1 B TYR 261 ? B TYR 261 
644  1 Y 1 B LEU 590 ? B LEU 590 
645  1 Y 1 B PRO 591 ? B PRO 591 
646  1 Y 1 B ASP 592 ? B ASP 592 
647  1 Y 1 B LEU 593 ? B LEU 593 
648  1 Y 1 B GLY 594 ? B GLY 594 
649  1 Y 1 B TRP 595 ? B TRP 595 
650  1 Y 1 B ASN 596 ? B ASN 596 
651  1 Y 1 B GLN 597 ? B GLN 597 
652  1 Y 1 B LEU 598 ? B LEU 598 
653  1 Y 1 B SER 599 ? B SER 599 
654  1 Y 1 B LYS 600 ? B LYS 600 
655  1 Y 1 B TYR 601 ? B TYR 601 
656  1 Y 1 B THR 602 ? B THR 602 
657  1 Y 1 B ILE 603 ? B ILE 603 
658  1 Y 1 B PHE 604 ? B PHE 604 
659  1 Y 1 B VAL 605 ? B VAL 605 
660  1 Y 1 B GLU 606 ? B GLU 606 
661  1 Y 1 B ASP 607 ? B ASP 607 
662  1 Y 1 B ILE 608 ? B ILE 608 
663  1 Y 1 B MET 609 ? B MET 609 
664  1 Y 1 B VAL 610 ? B VAL 610 
665  1 Y 1 B ARG 611 ? B ARG 611 
666  1 Y 1 B ASP 612 ? B ASP 612 
667  1 Y 1 B VAL 613 ? B VAL 613 
668  1 Y 1 B LYS 614 ? B LYS 614 
669  1 Y 1 B PHE 615 ? B PHE 615 
670  1 Y 1 B VAL 616 ? B VAL 616 
671  1 Y 1 B SER 617 ? B SER 617 
672  1 Y 1 B ALA 618 ? B ALA 618 
673  1 Y 1 B SER 619 ? B SER 619 
674  1 Y 1 B TYR 620 ? B TYR 620 
675  1 Y 1 B THR 621 ? B THR 621 
676  1 Y 1 B TYR 622 ? B TYR 622 
677  1 Y 1 B GLY 623 ? B GLY 623 
678  1 Y 1 B GLU 624 ? B GLU 624 
679  1 Y 1 B LEU 625 ? B LEU 625 
680  1 Y 1 B ARG 626 ? B ARG 626 
681  1 Y 1 B THR 627 ? B THR 627 
682  1 Y 1 B LEU 628 ? B LEU 628 
683  1 Y 1 B LEU 629 ? B LEU 629 
684  1 Y 1 B GLN 630 ? B GLN 630 
685  1 Y 1 B THR 631 ? B THR 631 
686  1 Y 1 B THR 632 ? B THR 632 
687  1 Y 1 B THR 633 ? B THR 633 
688  1 Y 1 B VAL 634 ? B VAL 634 
689  1 Y 1 B LYS 635 ? B LYS 635 
690  1 Y 1 B THR 636 ? B THR 636 
691  1 Y 1 B LEU 637 ? B LEU 637 
692  1 Y 1 B PRO 638 ? B PRO 638 
693  1 Y 1 B LEU 639 ? B LEU 639 
694  1 Y 1 B VAL 640 ? B VAL 640 
695  1 Y 1 B ASP 641 ? B ASP 641 
696  1 Y 1 B SER 642 ? B SER 642 
697  1 Y 1 B LYS 643 ? B LYS 643 
698  1 Y 1 B ASP 644 ? B ASP 644 
699  1 Y 1 B SER 645 ? B SER 645 
700  1 Y 1 B MET 646 ? B MET 646 
701  1 Y 1 B ILE 647 ? B ILE 647 
702  1 Y 1 B LEU 648 ? B LEU 648 
703  1 Y 1 B LEU 649 ? B LEU 649 
704  1 Y 1 B GLY 650 ? B GLY 650 
705  1 Y 1 B SER 651 ? B SER 651 
706  1 Y 1 B VAL 652 ? B VAL 652 
707  1 Y 1 B GLU 653 ? B GLU 653 
708  1 Y 1 B ARG 654 ? B ARG 654 
709  1 Y 1 B SER 655 ? B SER 655 
710  1 Y 1 B GLU 656 ? B GLU 656 
711  1 Y 1 B LEU 657 ? B LEU 657 
712  1 Y 1 B GLN 658 ? B GLN 658 
713  1 Y 1 B ALA 659 ? B ALA 659 
714  1 Y 1 B LEU 660 ? B LEU 660 
715  1 Y 1 B LEU 661 ? B LEU 661 
716  1 Y 1 B GLN 662 ? B GLN 662 
717  1 Y 1 B ARG 663 ? B ARG 663 
718  1 Y 1 B HIS 664 ? B HIS 664 
719  1 Y 1 B LEU 665 ? B LEU 665 
720  1 Y 1 B CYS 666 ? B CYS 666 
721  1 Y 1 B PRO 667 ? B PRO 667 
722  1 Y 1 B GLU 668 ? B GLU 668 
723  1 Y 1 B ARG 669 ? B ARG 669 
724  1 Y 1 B ARG 670 ? B ARG 670 
725  1 Y 1 B LEU 671 ? B LEU 671 
726  1 Y 1 B ARG 672 ? B ARG 672 
727  1 Y 1 B ALA 673 ? B ALA 673 
728  1 Y 1 B ALA 674 ? B ALA 674 
729  1 Y 1 B GLN 675 ? B GLN 675 
730  1 Y 1 B GLU 676 ? B GLU 676 
731  1 Y 1 B MET 677 ? B MET 677 
732  1 Y 1 B ALA 678 ? B ALA 678 
733  1 Y 1 B ARG 679 ? B ARG 679 
734  1 Y 1 B LYS 680 ? B LYS 680 
735  1 Y 1 B LEU 681 ? B LEU 681 
736  1 Y 1 B SER 682 ? B SER 682 
737  1 Y 1 B GLU 683 ? B GLU 683 
738  1 Y 1 B LEU 684 ? B LEU 684 
739  1 Y 1 B PRO 685 ? B PRO 685 
740  1 Y 1 B TYR 686 ? B TYR 686 
741  1 Y 1 B ASP 687 ? B ASP 687 
742  1 Y 1 B GLY 688 ? B GLY 688 
743  1 Y 1 B LYS 689 ? B LYS 689 
744  1 Y 1 B ALA 690 ? B ALA 690 
745  1 Y 1 B ARG 691 ? B ARG 691 
746  1 Y 1 B LEU 692 ? B LEU 692 
747  1 Y 1 B ALA 693 ? B ALA 693 
748  1 Y 1 B GLY 694 ? B GLY 694 
749  1 Y 1 B GLU 695 ? B GLU 695 
750  1 Y 1 B GLY 696 ? B GLY 696 
751  1 Y 1 B LEU 697 ? B LEU 697 
752  1 Y 1 B PRO 698 ? B PRO 698 
753  1 Y 1 B GLY 699 ? B GLY 699 
754  1 Y 1 B ALA 700 ? B ALA 700 
755  1 Y 1 B PRO 701 ? B PRO 701 
756  1 Y 1 B PRO 702 ? B PRO 702 
757  1 Y 1 B GLY 703 ? B GLY 703 
758  1 Y 1 B ARG 704 ? B ARG 704 
759  1 Y 1 B PRO 705 ? B PRO 705 
760  1 Y 1 B GLU 706 ? B GLU 706 
761  1 Y 1 B SER 707 ? B SER 707 
762  1 Y 1 B PHE 708 ? B PHE 708 
763  1 Y 1 B ALA 709 ? B ALA 709 
764  1 Y 1 B PHE 710 ? B PHE 710 
765  1 Y 1 B VAL 711 ? B VAL 711 
766  1 Y 1 B ASP 712 ? B ASP 712 
767  1 Y 1 B GLU 713 ? B GLU 713 
768  1 Y 1 B ASP 714 ? B ASP 714 
769  1 Y 1 B GLU 715 ? B GLU 715 
770  1 Y 1 B ASP 716 ? B ASP 716 
771  1 Y 1 B GLU 717 ? B GLU 717 
772  1 Y 1 B ASP 718 ? B ASP 718 
773  1 Y 1 B LEU 719 ? B LEU 719 
774  1 Y 1 B SER 720 ? B SER 720 
775  1 Y 1 B GLY 721 ? B GLY 721 
776  1 Y 1 B LYS 722 ? B LYS 722 
777  1 Y 1 B SER 723 ? B SER 723 
778  1 Y 1 B GLU 724 ? B GLU 724 
779  1 Y 1 B LEU 725 ? B LEU 725 
780  1 Y 1 B PRO 726 ? B PRO 726 
781  1 Y 1 B PRO 727 ? B PRO 727 
782  1 Y 1 B SER 728 ? B SER 728 
783  1 Y 1 B LEU 729 ? B LEU 729 
784  1 Y 1 B ALA 730 ? B ALA 730 
785  1 Y 1 B LEU 731 ? B LEU 731 
786  1 Y 1 B HIS 732 ? B HIS 732 
787  1 Y 1 B PRO 733 ? B PRO 733 
788  1 Y 1 B SER 734 ? B SER 734 
789  1 Y 1 B THR 735 ? B THR 735 
790  1 Y 1 B THR 736 ? B THR 736 
791  1 Y 1 B ALA 737 ? B ALA 737 
792  1 Y 1 B PRO 738 ? B PRO 738 
793  1 Y 1 B LEU 739 ? B LEU 739 
794  1 Y 1 B SER 740 ? B SER 740 
795  1 Y 1 B PRO 741 ? B PRO 741 
796  1 Y 1 B GLU 742 ? B GLU 742 
797  1 Y 1 B GLU 743 ? B GLU 743 
798  1 Y 1 B PRO 744 ? B PRO 744 
799  1 Y 1 B ASN 745 ? B ASN 745 
800  1 Y 1 B GLY 746 ? B GLY 746 
801  1 Y 1 B PRO 747 ? B PRO 747 
802  1 Y 1 B LEU 748 ? B LEU 748 
803  1 Y 1 B PRO 749 ? B PRO 749 
804  1 Y 1 B GLY 750 ? B GLY 750 
805  1 Y 1 B HIS 751 ? B HIS 751 
806  1 Y 1 B LYS 752 ? B LYS 752 
807  1 Y 1 B GLN 753 ? B GLN 753 
808  1 Y 1 B GLN 754 ? B GLN 754 
809  1 Y 1 B PRO 755 ? B PRO 755 
810  1 Y 1 B GLU 756 ? B GLU 756 
811  1 Y 1 B ALA 757 ? B ALA 757 
812  1 Y 1 B PRO 758 ? B PRO 758 
813  1 Y 1 B GLU 759 ? B GLU 759 
814  1 Y 1 B PRO 760 ? B PRO 760 
815  1 Y 1 B ALA 761 ? B ALA 761 
816  1 Y 1 B GLY 762 ? B GLY 762 
817  1 Y 1 B GLN 763 ? B GLN 763 
818  1 Y 1 B ARG 764 ? B ARG 764 
819  1 Y 1 B PRO 765 ? B PRO 765 
820  1 Y 1 B SER 766 ? B SER 766 
821  1 Y 1 B ILE 767 ? B ILE 767 
822  1 Y 1 B PHE 768 ? B PHE 768 
823  1 Y 1 B GLN 769 ? B GLN 769 
824  1 Y 1 B SER 770 ? B SER 770 
825  1 Y 1 B LEU 771 ? B LEU 771 
826  1 Y 1 B LEU 772 ? B LEU 772 
827  1 Y 1 B HIS 773 ? B HIS 773 
828  1 Y 1 B CYS 774 ? B CYS 774 
829  1 Y 1 B LEU 775 ? B LEU 775 
830  1 Y 1 B LEU 776 ? B LEU 776 
831  1 Y 1 B GLY 777 ? B GLY 777 
832  1 Y 1 B ARG 778 ? B ARG 778 
833  1 Y 1 B ALA 779 ? B ALA 779 
834  1 Y 1 B ARG 780 ? B ARG 780 
835  1 Y 1 B PRO 781 ? B PRO 781 
836  1 Y 1 B THR 782 ? B THR 782 
837  1 Y 1 B LYS 783 ? B LYS 783 
838  1 Y 1 B LYS 784 ? B LYS 784 
839  1 Y 1 B LYS 785 ? B LYS 785 
840  1 Y 1 B THR 786 ? B THR 786 
841  1 Y 1 B THR 787 ? B THR 787 
842  1 Y 1 B GLN 788 ? B GLN 788 
843  1 Y 1 B ASP 789 ? B ASP 789 
844  1 Y 1 B SER 790 ? B SER 790 
845  1 Y 1 B THR 791 ? B THR 791 
846  1 Y 1 B ASP 792 ? B ASP 792 
847  1 Y 1 B LEU 793 ? B LEU 793 
848  1 Y 1 B VAL 794 ? B VAL 794 
849  1 Y 1 B ASP 795 ? B ASP 795 
850  1 Y 1 B ASN 796 ? B ASN 796 
851  1 Y 1 B MET 797 ? B MET 797 
852  1 Y 1 B SER 798 ? B SER 798 
853  1 Y 1 B PRO 799 ? B PRO 799 
854  1 Y 1 B GLU 800 ? B GLU 800 
855  1 Y 1 B GLU 801 ? B GLU 801 
856  1 Y 1 B ILE 802 ? B ILE 802 
857  1 Y 1 B GLU 803 ? B GLU 803 
858  1 Y 1 B ALA 804 ? B ALA 804 
859  1 Y 1 B TRP 805 ? B TRP 805 
860  1 Y 1 B GLU 806 ? B GLU 806 
861  1 Y 1 B GLN 807 ? B GLN 807 
862  1 Y 1 B GLU 808 ? B GLU 808 
863  1 Y 1 B GLN 809 ? B GLN 809 
864  1 Y 1 B LEU 810 ? B LEU 810 
865  1 Y 1 B SER 811 ? B SER 811 
866  1 Y 1 B GLN 812 ? B GLN 812 
867  1 Y 1 B PRO 813 ? B PRO 813 
868  1 Y 1 B VAL 814 ? B VAL 814 
869  1 Y 1 B CYS 815 ? B CYS 815 
870  1 Y 1 B PHE 816 ? B PHE 816 
871  1 Y 1 B ASP 817 ? B ASP 817 
872  1 Y 1 B SER 818 ? B SER 818 
873  1 Y 1 B CYS 819 ? B CYS 819 
874  1 Y 1 B CYS 820 ? B CYS 820 
875  1 Y 1 B ILE 821 ? B ILE 821 
876  1 Y 1 B ASP 822 ? B ASP 822 
877  1 Y 1 B GLN 823 ? B GLN 823 
878  1 Y 1 B SER 824 ? B SER 824 
879  1 Y 1 B PRO 825 ? B PRO 825 
880  1 Y 1 B PHE 826 ? B PHE 826 
881  1 Y 1 B GLN 827 ? B GLN 827 
882  1 Y 1 B LEU 828 ? B LEU 828 
883  1 Y 1 B VAL 829 ? B VAL 829 
884  1 Y 1 B GLU 830 ? B GLU 830 
885  1 Y 1 B GLN 831 ? B GLN 831 
886  1 Y 1 B THR 832 ? B THR 832 
887  1 Y 1 B THR 833 ? B THR 833 
888  1 Y 1 B LEU 834 ? B LEU 834 
889  1 Y 1 B HIS 835 ? B HIS 835 
890  1 Y 1 B LYS 836 ? B LYS 836 
891  1 Y 1 B THR 837 ? B THR 837 
892  1 Y 1 B HIS 838 ? B HIS 838 
893  1 Y 1 B THR 839 ? B THR 839 
894  1 Y 1 B LEU 840 ? B LEU 840 
895  1 Y 1 B PHE 841 ? B PHE 841 
896  1 Y 1 B SER 842 ? B SER 842 
897  1 Y 1 B LEU 843 ? B LEU 843 
898  1 Y 1 B LEU 844 ? B LEU 844 
899  1 Y 1 B GLY 845 ? B GLY 845 
900  1 Y 1 B LEU 846 ? B LEU 846 
901  1 Y 1 B HIS 847 ? B HIS 847 
902  1 Y 1 B LEU 848 ? B LEU 848 
903  1 Y 1 B ALA 849 ? B ALA 849 
904  1 Y 1 B TYR 850 ? B TYR 850 
905  1 Y 1 B VAL 851 ? B VAL 851 
906  1 Y 1 B THR 852 ? B THR 852 
907  1 Y 1 B SER 853 ? B SER 853 
908  1 Y 1 B MET 854 ? B MET 854 
909  1 Y 1 B GLY 855 ? B GLY 855 
910  1 Y 1 B LYS 856 ? B LYS 856 
911  1 Y 1 B LEU 857 ? B LEU 857 
912  1 Y 1 B ARG 858 ? B ARG 858 
913  1 Y 1 B GLY 859 ? B GLY 859 
914  1 Y 1 B VAL 860 ? B VAL 860 
915  1 Y 1 B LEU 861 ? B LEU 861 
916  1 Y 1 B ALA 862 ? B ALA 862 
917  1 Y 1 B LEU 863 ? B LEU 863 
918  1 Y 1 B GLU 864 ? B GLU 864 
919  1 Y 1 B GLU 865 ? B GLU 865 
920  1 Y 1 B LEU 866 ? B LEU 866 
921  1 Y 1 B GLN 867 ? B GLN 867 
922  1 Y 1 B LYS 868 ? B LYS 868 
923  1 Y 1 B ALA 869 ? B ALA 869 
924  1 Y 1 B ILE 870 ? B ILE 870 
925  1 Y 1 B GLU 871 ? B GLU 871 
926  1 Y 1 B GLY 872 ? B GLY 872 
927  1 Y 1 B HIS 873 ? B HIS 873 
928  1 Y 1 B THR 874 ? B THR 874 
929  1 Y 1 B LYS 875 ? B LYS 875 
930  1 Y 1 B SER 876 ? B SER 876 
931  1 Y 1 B GLY 877 ? B GLY 877 
932  1 Y 1 B VAL 878 ? B VAL 878 
933  1 Y 1 B GLN 879 ? B GLN 879 
934  1 Y 1 B LEU 880 ? B LEU 880 
935  1 Y 1 B ARG 881 ? B ARG 881 
936  1 Y 1 B PRO 882 ? B PRO 882 
937  1 Y 1 B PRO 883 ? B PRO 883 
938  1 Y 1 B LEU 884 ? B LEU 884 
939  1 Y 1 B ALA 885 ? B ALA 885 
940  1 Y 1 B SER 886 ? B SER 886 
941  1 Y 1 B PHE 887 ? B PHE 887 
942  1 Y 1 B ARG 888 ? B ARG 888 
943  1 Y 1 B ASN 889 ? B ASN 889 
944  1 Y 1 B THR 890 ? B THR 890 
945  1 Y 1 B THR 891 ? B THR 891 
946  1 Y 1 B SER 892 ? B SER 892 
947  1 Y 1 B THR 893 ? B THR 893 
948  1 Y 1 B ARG 894 ? B ARG 894 
949  1 Y 1 B LYS 895 ? B LYS 895 
950  1 Y 1 B SER 896 ? B SER 896 
951  1 Y 1 B THR 897 ? B THR 897 
952  1 Y 1 B GLY 898 ? B GLY 898 
953  1 Y 1 B ALA 899 ? B ALA 899 
954  1 Y 1 B PRO 900 ? B PRO 900 
955  1 Y 1 B PRO 901 ? B PRO 901 
956  1 Y 1 B SER 902 ? B SER 902 
957  1 Y 1 B SER 903 ? B SER 903 
958  1 Y 1 B ALA 904 ? B ALA 904 
959  1 Y 1 B GLU 905 ? B GLU 905 
960  1 Y 1 B ASN 906 ? B ASN 906 
961  1 Y 1 B TRP 907 ? B TRP 907 
962  1 Y 1 B ASN 908 ? B ASN 908 
963  1 Y 1 B LEU 909 ? B LEU 909 
964  1 Y 1 B PRO 910 ? B PRO 910 
965  1 Y 1 B GLU 911 ? B GLU 911 
966  1 Y 1 B ASP 912 ? B ASP 912 
967  1 Y 1 B ARG 913 ? B ARG 913 
968  1 Y 1 B PRO 914 ? B PRO 914 
969  1 Y 1 B GLY 915 ? B GLY 915 
970  1 Y 1 B ALA 916 ? B ALA 916 
971  1 Y 1 B THR 917 ? B THR 917 
972  1 Y 1 B GLY 918 ? B GLY 918 
973  1 Y 1 B THR 919 ? B THR 919 
974  1 Y 1 B GLY 920 ? B GLY 920 
975  1 Y 1 B ASP 921 ? B ASP 921 
976  1 Y 1 B VAL 922 ? B VAL 922 
977  1 Y 1 B ILE 923 ? B ILE 923 
978  1 Y 1 B ALA 924 ? B ALA 924 
979  1 Y 1 B ALA 925 ? B ALA 925 
980  1 Y 1 B SER 926 ? B SER 926 
981  1 Y 1 B PRO 927 ? B PRO 927 
982  1 Y 1 B GLU 928 ? B GLU 928 
983  1 Y 1 B THR 929 ? B THR 929 
984  1 Y 1 B PRO 930 ? B PRO 930 
985  1 Y 1 B VAL 931 ? B VAL 931 
986  1 Y 1 B PRO 932 ? B PRO 932 
987  1 Y 1 B SER 933 ? B SER 933 
988  1 Y 1 B PRO 934 ? B PRO 934 
989  1 Y 1 B SER 935 ? B SER 935 
990  1 Y 1 B PRO 936 ? B PRO 936 
991  1 Y 1 B GLU 937 ? B GLU 937 
992  1 Y 1 B PRO 938 ? B PRO 938 
993  1 Y 1 B PRO 939 ? B PRO 939 
994  1 Y 1 B LEU 940 ? B LEU 940 
995  1 Y 1 B SER 941 ? B SER 941 
996  1 Y 1 B LEU 942 ? B LEU 942 
997  1 Y 1 B ALA 943 ? B ALA 943 
998  1 Y 1 B PRO 944 ? B PRO 944 
999  1 Y 1 B GLY 945 ? B GLY 945 
1000 1 Y 1 B LYS 946 ? B LYS 946 
1001 1 Y 1 B VAL 947 ? B VAL 947 
1002 1 Y 1 B GLU 948 ? B GLU 948 
1003 1 Y 1 B GLY 949 ? B GLY 949 
1004 1 Y 1 B GLU 950 ? B GLU 950 
1005 1 Y 1 B LEU 951 ? B LEU 951 
1006 1 Y 1 B GLU 952 ? B GLU 952 
1007 1 Y 1 B GLU 953 ? B GLU 953 
1008 1 Y 1 B LEU 954 ? B LEU 954 
1009 1 Y 1 B GLU 955 ? B GLU 955 
1010 1 Y 1 B LEU 956 ? B LEU 956 
1011 1 Y 1 B VAL 957 ? B VAL 957 
1012 1 Y 1 B GLU 958 ? B GLU 958 
1013 1 Y 1 B SER 959 ? B SER 959 
1014 1 Y 1 B PRO 960 ? B PRO 960 
1015 1 Y 1 B GLY 961 ? B GLY 961 
1016 1 Y 1 B LEU 962 ? B LEU 962 
1017 1 Y 1 B GLU 963 ? B GLU 963 
1018 1 Y 1 B GLU 964 ? B GLU 964 
1019 1 Y 1 B GLU 965 ? B GLU 965 
1020 1 Y 1 B LEU 966 ? B LEU 966 
1021 1 Y 1 B ALA 967 ? B ALA 967 
1022 1 Y 1 B ASP 968 ? B ASP 968 
1023 1 Y 1 B ILE 969 ? B ILE 969 
1024 1 Y 1 B LEU 970 ? B LEU 970 
1025 1 Y 1 B GLN 971 ? B GLN 971 
1026 1 Y 1 B GLY 972 ? B GLY 972 
1027 1 Y 1 B PRO 973 ? B PRO 973 
1028 1 Y 1 B SER 974 ? B SER 974 
1029 1 Y 1 B LEU 975 ? B LEU 975 
1030 1 Y 1 B ARG 976 ? B ARG 976 
1031 1 Y 1 B SER 977 ? B SER 977 
1032 1 Y 1 B THR 978 ? B THR 978 
1033 1 Y 1 B ASP 979 ? B ASP 979 
1034 1 Y 1 B GLU 980 ? B GLU 980 
1035 1 Y 1 B GLU 981 ? B GLU 981 
1036 1 Y 1 B ASP 982 ? B ASP 982 
1037 1 Y 1 B GLU 983 ? B GLU 983 
1038 1 Y 1 B ASP 984 ? B ASP 984 
1039 1 Y 1 B GLU 985 ? B GLU 985 
1040 1 Y 1 B LEU 986 ? B LEU 986 
1041 1 Y 1 B ILE 987 ? B ILE 987 
1042 1 Y 1 B LEU 988 ? B LEU 988 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SCN S    S N N 287 
SCN C    C N N 288 
SCN N    N N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SCN S   C    sing N N 275 
SCN C   N    trip N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-10-29 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8WXI 
_em_admin.last_update        2024-11-20 
_em_admin.map_release_date   2024-11-20 
_em_admin.title              'human CLC-1 D136G delayed rectification' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8WXI 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLY A 1 115 ? 147.736 119.029 114.963 1.00 307.19 ?  115  GLY A N   1 
ATOM   2    C CA  . GLY A 1 115 ? 148.135 119.519 113.658 1.00 307.19 ?  115  GLY A CA  1 
ATOM   3    C C   . GLY A 1 115 ? 148.415 121.000 113.729 1.00 307.19 ?  115  GLY A C   1 
ATOM   4    O O   . GLY A 1 115 ? 148.396 121.570 114.810 1.00 307.19 ?  115  GLY A O   1 
ATOM   5    N N   . GLU A 1 116 ? 148.679 121.626 112.587 1.00 330.29 ?  116  GLU A N   1 
ATOM   6    C CA  . GLU A 1 116 ? 148.981 123.057 112.560 1.00 330.29 ?  116  GLU A CA  1 
ATOM   7    C C   . GLU A 1 116 ? 147.805 123.875 113.061 1.00 330.29 ?  116  GLU A C   1 
ATOM   8    O O   . GLU A 1 116 ? 147.993 124.908 113.696 1.00 330.29 ?  116  GLU A O   1 
ATOM   9    C CB  . GLU A 1 116 ? 149.384 123.513 111.159 1.00 330.29 ?  116  GLU A CB  1 
ATOM   10   C CG  . GLU A 1 116 ? 150.571 124.465 111.151 1.00 330.29 ?  116  GLU A CG  1 
ATOM   11   C CD  . GLU A 1 116 ? 150.220 125.849 110.633 1.00 330.29 ?  116  GLU A CD  1 
ATOM   12   O OE1 . GLU A 1 116 ? 149.162 126.389 111.021 1.00 330.29 ?  116  GLU A OE1 1 
ATOM   13   O OE2 . GLU A 1 116 ? 151.011 126.398 109.839 1.00 330.29 -1 116  GLU A OE2 1 
ATOM   14   N N   . ASP A 1 117 ? 146.590 123.413 112.788 1.00 314.50 ?  117  ASP A N   1 
ATOM   15   C CA  . ASP A 1 117 ? 145.413 124.116 113.282 1.00 314.50 ?  117  ASP A CA  1 
ATOM   16   C C   . ASP A 1 117 ? 145.296 123.989 114.790 1.00 314.50 ?  117  ASP A C   1 
ATOM   17   O O   . ASP A 1 117 ? 144.839 124.907 115.436 1.00 314.50 ?  117  ASP A O   1 
ATOM   18   C CB  . ASP A 1 117 ? 144.127 123.656 112.580 1.00 314.50 ?  117  ASP A CB  1 
ATOM   19   C CG  . ASP A 1 117 ? 143.581 122.357 113.138 1.00 314.50 ?  117  ASP A CG  1 
ATOM   20   O OD1 . ASP A 1 117 ? 144.218 121.302 112.923 1.00 314.50 ?  117  ASP A OD1 1 
ATOM   21   O OD2 . ASP A 1 117 ? 142.521 122.389 113.796 1.00 314.50 -1 117  ASP A OD2 1 
ATOM   22   N N   . GLY A 1 118 ? 145.732 122.872 115.357 1.00 305.92 ?  118  GLY A N   1 
ATOM   23   C CA  . GLY A 1 118 ? 145.701 122.708 116.795 1.00 305.92 ?  118  GLY A CA  1 
ATOM   24   C C   . GLY A 1 118 ? 146.655 123.674 117.451 1.00 305.92 ?  118  GLY A C   1 
ATOM   25   O O   . GLY A 1 118 ? 146.352 124.215 118.508 1.00 305.92 ?  118  GLY A O   1 
ATOM   26   N N   . ILE A 1 119 ? 147.805 123.901 116.825 1.00 303.10 ?  119  ILE A N   1 
ATOM   27   C CA  . ILE A 1 119 ? 148.765 124.859 117.349 1.00 303.10 ?  119  ILE A CA  1 
ATOM   28   C C   . ILE A 1 119 ? 148.174 126.247 117.228 1.00 303.10 ?  119  ILE A C   1 
ATOM   29   O O   . ILE A 1 119 ? 148.317 127.057 118.128 1.00 303.10 ?  119  ILE A O   1 
ATOM   30   C CB  . ILE A 1 119 ? 150.103 124.791 116.590 1.00 303.10 ?  119  ILE A CB  1 
ATOM   31   C CG1 . ILE A 1 119 ? 150.602 123.353 116.518 1.00 303.10 ?  119  ILE A CG1 1 
ATOM   32   C CG2 . ILE A 1 119 ? 151.164 125.645 117.265 1.00 303.10 ?  119  ILE A CG2 1 
ATOM   33   C CD1 . ILE A 1 119 ? 151.676 123.137 115.476 1.00 303.10 ?  119  ILE A CD1 1 
ATOM   34   N N   . PHE A 1 120 ? 147.489 126.519 116.126 1.00 314.42 ?  120  PHE A N   1 
ATOM   35   C CA  . PHE A 1 120 ? 146.835 127.808 115.955 1.00 314.42 ?  120  PHE A CA  1 
ATOM   36   C C   . PHE A 1 120 ? 145.887 128.090 117.108 1.00 314.42 ?  120  PHE A C   1 
ATOM   37   O O   . PHE A 1 120 ? 145.899 129.181 117.653 1.00 314.42 ?  120  PHE A O   1 
ATOM   38   C CB  . PHE A 1 120 ? 146.113 127.863 114.607 1.00 314.42 ?  120  PHE A CB  1 
ATOM   39   C CG  . PHE A 1 120 ? 145.219 129.055 114.432 1.00 314.42 ?  120  PHE A CG  1 
ATOM   40   C CD1 . PHE A 1 120 ? 145.753 130.316 114.245 1.00 314.42 ?  120  PHE A CD1 1 
ATOM   41   C CD2 . PHE A 1 120 ? 143.840 128.908 114.432 1.00 314.42 ?  120  PHE A CD2 1 
ATOM   42   C CE1 . PHE A 1 120 ? 144.931 131.410 114.076 1.00 314.42 ?  120  PHE A CE1 1 
ATOM   43   C CE2 . PHE A 1 120 ? 143.013 129.999 114.267 1.00 314.42 ?  120  PHE A CE2 1 
ATOM   44   C CZ  . PHE A 1 120 ? 143.561 131.251 114.087 1.00 314.42 ?  120  PHE A CZ  1 
ATOM   45   N N   . LEU A 1 121 ? 145.087 127.106 117.497 1.00 306.71 ?  121  LEU A N   1 
ATOM   46   C CA  . LEU A 1 121 ? 144.138 127.291 118.587 1.00 306.71 ?  121  LEU A CA  1 
ATOM   47   C C   . LEU A 1 121 ? 144.817 127.424 119.942 1.00 306.71 ?  121  LEU A C   1 
ATOM   48   O O   . LEU A 1 121 ? 144.357 128.169 120.796 1.00 306.71 ?  121  LEU A O   1 
ATOM   49   C CB  . LEU A 1 121 ? 143.134 126.145 118.615 1.00 306.71 ?  121  LEU A CB  1 
ATOM   50   C CG  . LEU A 1 121 ? 142.455 125.778 117.304 1.00 306.71 ?  121  LEU A CG  1 
ATOM   51   C CD1 . LEU A 1 121 ? 141.778 124.423 117.380 1.00 306.71 ?  121  LEU A CD1 1 
ATOM   52   C CD2 . LEU A 1 121 ? 141.506 126.858 116.835 1.00 306.71 ?  121  LEU A CD2 1 
ATOM   53   N N   . VAL A 1 122 ? 145.909 126.705 120.148 1.00 300.11 ?  122  VAL A N   1 
ATOM   54   C CA  . VAL A 1 122 ? 146.652 126.825 121.396 1.00 300.11 ?  122  VAL A CA  1 
ATOM   55   C C   . VAL A 1 122 ? 147.222 128.229 121.463 1.00 300.11 ?  122  VAL A C   1 
ATOM   56   O O   . VAL A 1 122 ? 147.103 128.902 122.480 1.00 300.11 ?  122  VAL A O   1 
ATOM   57   C CB  . VAL A 1 122 ? 147.760 125.752 121.490 1.00 300.11 ?  122  VAL A CB  1 
ATOM   58   C CG1 . VAL A 1 122 ? 148.954 126.220 122.308 1.00 300.11 ?  122  VAL A CG1 1 
ATOM   59   C CG2 . VAL A 1 122 ? 147.199 124.466 122.069 1.00 300.11 ?  122  VAL A CG2 1 
ATOM   60   N N   . LEU A 1 123 ? 147.786 128.701 120.358 1.00 294.58 ?  123  LEU A N   1 
ATOM   61   C CA  . LEU A 1 123 ? 148.358 130.034 120.324 1.00 294.58 ?  123  LEU A CA  1 
ATOM   62   C C   . LEU A 1 123 ? 147.276 131.068 120.517 1.00 294.58 ?  123  LEU A C   1 
ATOM   63   O O   . LEU A 1 123 ? 147.480 132.029 121.237 1.00 294.58 ?  123  LEU A O   1 
ATOM   64   C CB  . LEU A 1 123 ? 149.082 130.267 119.006 1.00 294.58 ?  123  LEU A CB  1 
ATOM   65   C CG  . LEU A 1 123 ? 150.605 130.354 119.070 1.00 294.58 ?  123  LEU A CG  1 
ATOM   66   C CD1 . LEU A 1 123 ? 151.042 131.441 120.038 1.00 294.58 ?  123  LEU A CD1 1 
ATOM   67   C CD2 . LEU A 1 123 ? 151.211 129.016 119.455 1.00 294.58 ?  123  LEU A CD2 1 
ATOM   68   N N   . LEU A 1 124 ? 146.124 130.873 119.885 1.00 286.31 ?  124  LEU A N   1 
ATOM   69   C CA  . LEU A 1 124 ? 145.005 131.788 120.055 1.00 286.31 ?  124  LEU A CA  1 
ATOM   70   C C   . LEU A 1 124 ? 144.685 131.924 121.518 1.00 286.31 ?  124  LEU A C   1 
ATOM   71   O O   . LEU A 1 124 ? 144.783 133.004 122.069 1.00 286.31 ?  124  LEU A O   1 
ATOM   72   C CB  . LEU A 1 124 ? 143.762 131.264 119.343 1.00 286.31 ?  124  LEU A CB  1 
ATOM   73   C CG  . LEU A 1 124 ? 143.487 131.719 117.918 1.00 286.31 ?  124  LEU A CG  1 
ATOM   74   C CD1 . LEU A 1 124 ? 142.036 132.127 117.756 1.00 286.31 ?  124  LEU A CD1 1 
ATOM   75   C CD2 . LEU A 1 124 ? 144.403 132.870 117.573 1.00 286.31 ?  124  LEU A CD2 1 
ATOM   76   N N   . GLY A 1 125 ? 144.307 130.823 122.151 1.00 272.55 ?  125  GLY A N   1 
ATOM   77   C CA  . GLY A 1 125 ? 143.960 130.852 123.556 1.00 272.55 ?  125  GLY A CA  1 
ATOM   78   C C   . GLY A 1 125 ? 145.014 131.478 124.427 1.00 272.55 ?  125  GLY A C   1 
ATOM   79   O O   . GLY A 1 125 ? 144.712 132.358 125.218 1.00 272.55 ?  125  GLY A O   1 
ATOM   80   N N   . LEU A 1 126 ? 146.256 131.042 124.276 1.00 275.46 ?  126  LEU A N   1 
ATOM   81   C CA  . LEU A 1 126 ? 147.347 131.585 125.068 1.00 275.46 ?  126  LEU A CA  1 
ATOM   82   C C   . LEU A 1 126 ? 147.472 133.081 124.904 1.00 275.46 ?  126  LEU A C   1 
ATOM   83   O O   . LEU A 1 126 ? 147.418 133.811 125.882 1.00 275.46 ?  126  LEU A O   1 
ATOM   84   C CB  . LEU A 1 126 ? 148.663 130.914 124.678 1.00 275.46 ?  126  LEU A CB  1 
ATOM   85   C CG  . LEU A 1 126 ? 149.955 131.436 125.296 1.00 275.46 ?  126  LEU A CG  1 
ATOM   86   C CD1 . LEU A 1 126 ? 150.207 130.785 126.644 1.00 275.46 ?  126  LEU A CD1 1 
ATOM   87   C CD2 . LEU A 1 126 ? 151.114 131.190 124.345 1.00 275.46 ?  126  LEU A CD2 1 
ATOM   88   N N   . LEU A 1 127 ? 147.609 133.546 123.671 1.00 310.34 ?  127  LEU A N   1 
ATOM   89   C CA  . LEU A 1 127 ? 147.820 134.967 123.436 1.00 310.34 ?  127  LEU A CA  1 
ATOM   90   C C   . LEU A 1 127 ? 146.640 135.801 123.865 1.00 310.34 ?  127  LEU A C   1 
ATOM   91   O O   . LEU A 1 127 ? 146.815 136.853 124.445 1.00 310.34 ?  127  LEU A O   1 
ATOM   92   C CB  . LEU A 1 127 ? 148.133 135.235 121.969 1.00 310.34 ?  127  LEU A CB  1 
ATOM   93   C CG  . LEU A 1 127 ? 149.589 135.074 121.532 1.00 310.34 ?  127  LEU A CG  1 
ATOM   94   C CD1 . LEU A 1 127 ? 149.972 136.193 120.579 1.00 310.34 ?  127  LEU A CD1 1 
ATOM   95   C CD2 . LEU A 1 127 ? 150.536 135.046 122.722 1.00 310.34 ?  127  LEU A CD2 1 
ATOM   96   N N   . MET A 1 128 ? 145.437 135.325 123.586 1.00 291.41 ?  128  MET A N   1 
ATOM   97   C CA  . MET A 1 128 ? 144.245 136.050 123.977 1.00 291.41 ?  128  MET A CA  1 
ATOM   98   C C   . MET A 1 128 ? 144.177 136.224 125.470 1.00 291.41 ?  128  MET A C   1 
ATOM   99   O O   . MET A 1 128 ? 143.923 137.317 125.951 1.00 291.41 ?  128  MET A O   1 
ATOM   100  C CB  . MET A 1 128 ? 142.988 135.356 123.473 1.00 291.41 ?  128  MET A CB  1 
ATOM   101  C CG  . MET A 1 128 ? 142.365 136.069 122.295 1.00 291.41 ?  128  MET A CG  1 
ATOM   102  S SD  . MET A 1 128 ? 143.648 136.675 121.189 1.00 291.41 ?  128  MET A SD  1 
ATOM   103  C CE  . MET A 1 128 ? 143.705 138.412 121.624 1.00 291.41 ?  128  MET A CE  1 
ATOM   104  N N   . ALA A 1 129 ? 144.399 135.147 126.205 1.00 293.14 ?  129  ALA A N   1 
ATOM   105  C CA  . ALA A 1 129 ? 144.334 135.218 127.647 1.00 293.14 ?  129  ALA A CA  1 
ATOM   106  C C   . ALA A 1 129 ? 145.386 136.152 128.174 1.00 293.14 ?  129  ALA A C   1 
ATOM   107  O O   . ALA A 1 129 ? 145.121 136.909 129.084 1.00 293.14 ?  129  ALA A O   1 
ATOM   108  C CB  . ALA A 1 129 ? 144.508 133.850 128.252 1.00 293.14 ?  129  ALA A CB  1 
ATOM   109  N N   . LEU A 1 130 ? 146.581 136.105 127.602 1.00 300.42 ?  130  LEU A N   1 
ATOM   110  C CA  . LEU A 1 130 ? 147.656 136.979 128.037 1.00 300.42 ?  130  LEU A CA  1 
ATOM   111  C C   . LEU A 1 130 ? 147.292 138.429 127.814 1.00 300.42 ?  130  LEU A C   1 
ATOM   112  O O   . LEU A 1 130 ? 147.389 139.231 128.727 1.00 300.42 ?  130  LEU A O   1 
ATOM   113  C CB  . LEU A 1 130 ? 148.951 136.643 127.308 1.00 300.42 ?  130  LEU A CB  1 
ATOM   114  C CG  . LEU A 1 130 ? 149.664 135.381 127.779 1.00 300.42 ?  130  LEU A CG  1 
ATOM   115  C CD1 . LEU A 1 130 ? 150.875 135.103 126.906 1.00 300.42 ?  130  LEU A CD1 1 
ATOM   116  C CD2 . LEU A 1 130 ? 150.058 135.497 129.240 1.00 300.42 ?  130  LEU A CD2 1 
ATOM   117  N N   . VAL A 1 131 ? 146.856 138.766 126.607 1.00 275.05 ?  131  VAL A N   1 
ATOM   118  C CA  . VAL A 1 131 ? 146.457 140.133 126.292 1.00 275.05 ?  131  VAL A CA  1 
ATOM   119  C C   . VAL A 1 131 ? 145.283 140.570 127.165 1.00 275.05 ?  131  VAL A C   1 
ATOM   120  O O   . VAL A 1 131 ? 145.306 141.654 127.735 1.00 275.05 ?  131  VAL A O   1 
ATOM   121  C CB  . VAL A 1 131 ? 146.142 140.273 124.787 1.00 275.05 ?  131  VAL A CB  1 
ATOM   122  C CG1 . VAL A 1 131 ? 145.512 141.612 124.465 1.00 275.05 ?  131  VAL A CG1 1 
ATOM   123  C CG2 . VAL A 1 131 ? 147.412 140.100 123.971 1.00 275.05 ?  131  VAL A CG2 1 
ATOM   124  N N   . SER A 1 132 ? 144.280 139.716 127.309 1.00 258.77 ?  132  SER A N   1 
ATOM   125  C CA  . SER A 1 132 ? 143.125 140.038 128.134 1.00 258.77 ?  132  SER A CA  1 
ATOM   126  C C   . SER A 1 132 ? 143.491 140.261 129.580 1.00 258.77 ?  132  SER A C   1 
ATOM   127  O O   . SER A 1 132 ? 143.002 141.191 130.207 1.00 258.77 ?  132  SER A O   1 
ATOM   128  C CB  . SER A 1 132 ? 142.104 138.915 128.067 1.00 258.77 ?  132  SER A CB  1 
ATOM   129  O OG  . SER A 1 132 ? 141.037 139.154 128.964 1.00 258.77 ?  132  SER A OG  1 
ATOM   130  N N   . TRP A 1 133 ? 144.338 139.399 130.122 1.00 271.73 ?  133  TRP A N   1 
ATOM   131  C CA  . TRP A 1 133 ? 144.745 139.533 131.502 1.00 271.73 ?  133  TRP A CA  1 
ATOM   132  C C   . TRP A 1 133 ? 145.534 140.801 131.673 1.00 271.73 ?  133  TRP A C   1 
ATOM   133  O O   . TRP A 1 133 ? 145.320 141.521 132.625 1.00 271.73 ?  133  TRP A O   1 
ATOM   134  C CB  . TRP A 1 133 ? 145.586 138.336 131.942 1.00 271.73 ?  133  TRP A CB  1 
ATOM   135  C CG  . TRP A 1 133 ? 145.871 138.296 133.400 1.00 271.73 ?  133  TRP A CG  1 
ATOM   136  C CD1 . TRP A 1 133 ? 145.088 137.758 134.374 1.00 271.73 ?  133  TRP A CD1 1 
ATOM   137  C CD2 . TRP A 1 133 ? 147.030 138.815 134.057 1.00 271.73 ?  133  TRP A CD2 1 
ATOM   138  N NE1 . TRP A 1 133 ? 145.684 137.912 135.599 1.00 271.73 ?  133  TRP A NE1 1 
ATOM   139  C CE2 . TRP A 1 133 ? 146.878 138.560 135.430 1.00 271.73 ?  133  TRP A CE2 1 
ATOM   140  C CE3 . TRP A 1 133 ? 148.179 139.475 133.616 1.00 271.73 ?  133  TRP A CE3 1 
ATOM   141  C CZ2 . TRP A 1 133 ? 147.830 138.938 136.361 1.00 271.73 ?  133  TRP A CZ2 1 
ATOM   142  C CZ3 . TRP A 1 133 ? 149.120 139.851 134.543 1.00 271.73 ?  133  TRP A CZ3 1 
ATOM   143  C CH2 . TRP A 1 133 ? 148.943 139.581 135.901 1.00 271.73 ?  133  TRP A CH2 1 
ATOM   144  N N   . SER A 1 134 ? 146.453 141.075 130.758 1.00 256.83 ?  134  SER A N   1 
ATOM   145  C CA  . SER A 1 134 ? 147.279 142.263 130.856 1.00 256.83 ?  134  SER A CA  1 
ATOM   146  C C   . SER A 1 134 ? 146.424 143.505 130.849 1.00 256.83 ?  134  SER A C   1 
ATOM   147  O O   . SER A 1 134 ? 146.628 144.398 131.657 1.00 256.83 ?  134  SER A O   1 
ATOM   148  C CB  . SER A 1 134 ? 148.277 142.318 129.709 1.00 256.83 ?  134  SER A CB  1 
ATOM   149  O OG  . SER A 1 134 ? 149.167 141.220 129.763 1.00 256.83 ?  134  SER A OG  1 
ATOM   150  N N   . MET A 1 135 ? 145.460 143.567 129.942 1.00 225.39 ?  135  MET A N   1 
ATOM   151  C CA  . MET A 1 135 ? 144.553 144.698 129.899 1.00 225.39 ?  135  MET A CA  1 
ATOM   152  C C   . MET A 1 135 ? 143.800 144.796 131.196 1.00 225.39 ?  135  MET A C   1 
ATOM   153  O O   . MET A 1 135 ? 143.797 145.838 131.820 1.00 225.39 ?  135  MET A O   1 
ATOM   154  C CB  . MET A 1 135 ? 143.564 144.533 128.761 1.00 225.39 ?  135  MET A CB  1 
ATOM   155  C CG  . MET A 1 135 ? 144.111 144.962 127.420 1.00 225.39 ?  135  MET A CG  1 
ATOM   156  S SD  . MET A 1 135 ? 142.788 145.446 126.309 1.00 225.39 ?  135  MET A SD  1 
ATOM   157  C CE  . MET A 1 135 ? 142.943 144.145 125.103 1.00 225.39 ?  135  MET A CE  1 
ATOM   158  N N   . GLY A 1 136 ? 143.169 143.706 131.610 1.00 217.14 ?  136  GLY A N   1 
ATOM   159  C CA  . GLY A 1 136 ? 142.428 143.691 132.855 1.00 217.14 ?  136  GLY A CA  1 
ATOM   160  C C   . GLY A 1 136 ? 143.264 144.127 134.029 1.00 217.14 ?  136  GLY A C   1 
ATOM   161  O O   . GLY A 1 136 ? 142.782 144.852 134.883 1.00 217.14 ?  136  GLY A O   1 
ATOM   162  N N   . TYR A 1 137 ? 144.516 143.698 134.073 1.00 223.63 ?  137  TYR A N   1 
ATOM   163  C CA  . TYR A 1 137 ? 145.414 144.081 135.144 1.00 223.63 ?  137  TYR A CA  1 
ATOM   164  C C   . TYR A 1 137 ? 145.625 145.575 135.171 1.00 223.63 ?  137  TYR A C   1 
ATOM   165  O O   . TYR A 1 137 ? 145.369 146.212 136.175 1.00 223.63 ?  137  TYR A O   1 
ATOM   166  C CB  . TYR A 1 137 ? 146.757 143.387 134.979 1.00 223.63 ?  137  TYR A CB  1 
ATOM   167  C CG  . TYR A 1 137 ? 147.525 143.292 136.263 1.00 223.63 ?  137  TYR A CG  1 
ATOM   168  C CD1 . TYR A 1 137 ? 147.048 142.531 137.315 1.00 223.63 ?  137  TYR A CD1 1 
ATOM   169  C CD2 . TYR A 1 137 ? 148.717 143.976 136.431 1.00 223.63 ?  137  TYR A CD2 1 
ATOM   170  C CE1 . TYR A 1 137 ? 147.745 142.442 138.498 1.00 223.63 ?  137  TYR A CE1 1 
ATOM   171  C CE2 . TYR A 1 137 ? 149.421 143.896 137.613 1.00 223.63 ?  137  TYR A CE2 1 
ATOM   172  C CZ  . TYR A 1 137 ? 148.929 143.126 138.643 1.00 223.63 ?  137  TYR A CZ  1 
ATOM   173  O OH  . TYR A 1 137 ? 149.625 143.041 139.825 1.00 223.63 ?  137  TYR A OH  1 
ATOM   174  N N   . VAL A 1 138 ? 146.087 146.142 134.067 1.00 233.63 ?  138  VAL A N   1 
ATOM   175  C CA  . VAL A 1 138 ? 146.375 147.568 134.031 1.00 233.63 ?  138  VAL A CA  1 
ATOM   176  C C   . VAL A 1 138 ? 145.112 148.402 134.221 1.00 233.63 ?  138  VAL A C   1 
ATOM   177  O O   . VAL A 1 138 ? 145.145 149.433 134.878 1.00 233.63 ?  138  VAL A O   1 
ATOM   178  C CB  . VAL A 1 138 ? 147.138 147.949 132.746 1.00 233.63 ?  138  VAL A CB  1 
ATOM   179  C CG1 . VAL A 1 138 ? 147.563 149.409 132.766 1.00 233.63 ?  138  VAL A CG1 1 
ATOM   180  C CG2 . VAL A 1 138 ? 148.365 147.067 132.592 1.00 233.63 ?  138  VAL A CG2 1 
ATOM   181  N N   . SER A 1 139 ? 143.984 147.941 133.694 1.00 209.26 ?  139  SER A N   1 
ATOM   182  C CA  . SER A 1 139 ? 142.728 148.658 133.867 1.00 209.26 ?  139  SER A CA  1 
ATOM   183  C C   . SER A 1 139 ? 142.277 148.635 135.314 1.00 209.26 ?  139  SER A C   1 
ATOM   184  O O   . SER A 1 139 ? 141.703 149.598 135.800 1.00 209.26 ?  139  SER A O   1 
ATOM   185  C CB  . SER A 1 139 ? 141.654 148.076 132.960 1.00 209.26 ?  139  SER A CB  1 
ATOM   186  O OG  . SER A 1 139 ? 140.985 146.995 133.580 1.00 209.26 ?  139  SER A OG  1 
ATOM   187  N N   . ALA A 1 140 ? 142.552 147.548 136.019 1.00 212.88 ?  140  ALA A N   1 
ATOM   188  C CA  . ALA A 1 140 ? 142.204 147.468 137.425 1.00 212.88 ?  140  ALA A CA  1 
ATOM   189  C C   . ALA A 1 140 ? 143.150 148.302 138.253 1.00 212.88 ?  140  ALA A C   1 
ATOM   190  O O   . ALA A 1 140 ? 142.745 148.879 139.245 1.00 212.88 ?  140  ALA A O   1 
ATOM   191  C CB  . ALA A 1 140 ? 142.234 146.036 137.897 1.00 212.88 ?  140  ALA A CB  1 
ATOM   192  N N   . LYS A 1 141 ? 144.406 148.385 137.830 1.00 223.66 ?  141  LYS A N   1 
ATOM   193  C CA  . LYS A 1 141 ? 145.400 149.183 138.544 1.00 223.66 ?  141  LYS A CA  1 
ATOM   194  C C   . LYS A 1 141 ? 145.072 150.644 138.345 1.00 223.66 ?  141  LYS A C   1 
ATOM   195  O O   . LYS A 1 141 ? 145.344 151.461 139.215 1.00 223.66 ?  141  LYS A O   1 
ATOM   196  C CB  . LYS A 1 141 ? 146.809 148.900 138.022 1.00 223.66 ?  141  LYS A CB  1 
ATOM   197  C CG  . LYS A 1 141 ? 147.431 147.583 138.466 1.00 223.66 ?  141  LYS A CG  1 
ATOM   198  C CD  . LYS A 1 141 ? 146.778 147.021 139.715 1.00 223.66 ?  141  LYS A CD  1 
ATOM   199  C CE  . LYS A 1 141 ? 147.767 146.242 140.562 1.00 223.66 ?  141  LYS A CE  1 
ATOM   200  N NZ  . LYS A 1 141 ? 149.168 146.493 140.126 1.00 223.66 1  141  LYS A NZ  1 
ATOM   201  N N   . SER A 1 142 ? 144.495 150.980 137.197 1.00 217.81 ?  142  SER A N   1 
ATOM   202  C CA  . SER A 1 142 ? 144.098 152.348 136.923 1.00 217.81 ?  142  SER A CA  1 
ATOM   203  C C   . SER A 1 142 ? 142.856 152.701 137.714 1.00 217.81 ?  142  SER A C   1 
ATOM   204  O O   . SER A 1 142 ? 142.709 153.822 138.169 1.00 217.81 ?  142  SER A O   1 
ATOM   205  C CB  . SER A 1 142 ? 143.832 152.520 135.436 1.00 217.81 ?  142  SER A CB  1 
ATOM   206  O OG  . SER A 1 142 ? 143.105 153.699 135.200 1.00 217.81 ?  142  SER A OG  1 
ATOM   207  N N   . LEU A 1 143 ? 141.965 151.737 137.901 1.00 215.31 ?  143  LEU A N   1 
ATOM   208  C CA  . LEU A 1 143 ? 140.770 151.972 138.688 1.00 215.31 ?  143  LEU A CA  1 
ATOM   209  C C   . LEU A 1 143 ? 141.142 152.092 140.144 1.00 215.31 ?  143  LEU A C   1 
ATOM   210  O O   . LEU A 1 143 ? 140.518 152.834 140.889 1.00 215.31 ?  143  LEU A O   1 
ATOM   211  C CB  . LEU A 1 143 ? 139.795 150.819 138.508 1.00 215.31 ?  143  LEU A CB  1 
ATOM   212  C CG  . LEU A 1 143 ? 138.428 151.138 137.915 1.00 215.31 ?  143  LEU A CG  1 
ATOM   213  C CD1 . LEU A 1 143 ? 138.385 152.559 137.383 1.00 215.31 ?  143  LEU A CD1 1 
ATOM   214  C CD2 . LEU A 1 143 ? 138.083 150.137 136.830 1.00 215.31 ?  143  LEU A CD2 1 
ATOM   215  N N   . GLN A 1 144 ? 142.166 151.362 140.559 1.00 242.10 ?  144  GLN A N   1 
ATOM   216  C CA  . GLN A 1 144 ? 142.625 151.451 141.930 1.00 242.10 ?  144  GLN A CA  1 
ATOM   217  C C   . GLN A 1 144 ? 143.229 152.810 142.171 1.00 242.10 ?  144  GLN A C   1 
ATOM   218  O O   . GLN A 1 144 ? 142.993 153.410 143.209 1.00 242.10 ?  144  GLN A O   1 
ATOM   219  C CB  . GLN A 1 144 ? 143.654 150.366 142.224 1.00 242.10 ?  144  GLN A CB  1 
ATOM   220  C CG  . GLN A 1 144 ? 143.045 149.046 142.656 1.00 242.10 ?  144  GLN A CG  1 
ATOM   221  C CD  . GLN A 1 144 ? 143.922 147.869 142.294 1.00 242.10 ?  144  GLN A CD  1 
ATOM   222  O OE1 . GLN A 1 144 ? 143.465 146.898 141.690 1.00 242.10 ?  144  GLN A OE1 1 
ATOM   223  N NE2 . GLN A 1 144 ? 145.194 147.950 142.662 1.00 242.10 ?  144  GLN A NE2 1 
ATOM   224  N N   . ALA A 1 145 ? 144.000 153.308 141.213 1.00 229.27 ?  145  ALA A N   1 
ATOM   225  C CA  . ALA A 1 145 ? 144.590 154.630 141.337 1.00 229.27 ?  145  ALA A CA  1 
ATOM   226  C C   . ALA A 1 145 ? 143.513 155.683 141.350 1.00 229.27 ?  145  ALA A C   1 
ATOM   227  O O   . ALA A 1 145 ? 143.615 156.640 142.089 1.00 229.27 ?  145  ALA A O   1 
ATOM   228  C CB  . ALA A 1 145 ? 145.559 154.884 140.204 1.00 229.27 ?  145  ALA A CB  1 
ATOM   229  N N   . TYR A 1 146 ? 142.482 155.515 140.533 1.00 220.90 ?  146  TYR A N   1 
ATOM   230  C CA  . TYR A 1 146 ? 141.362 156.447 140.508 1.00 220.90 ?  146  TYR A CA  1 
ATOM   231  C C   . TYR A 1 146 ? 140.767 156.556 141.896 1.00 220.90 ?  146  TYR A C   1 
ATOM   232  O O   . TYR A 1 146 ? 140.641 157.649 142.434 1.00 220.90 ?  146  TYR A O   1 
ATOM   233  C CB  . TYR A 1 146 ? 140.334 155.904 139.523 1.00 220.90 ?  146  TYR A CB  1 
ATOM   234  C CG  . TYR A 1 146 ? 139.135 156.752 139.202 1.00 220.90 ?  146  TYR A CG  1 
ATOM   235  C CD1 . TYR A 1 146 ? 139.141 158.128 139.371 1.00 220.90 ?  146  TYR A CD1 1 
ATOM   236  C CD2 . TYR A 1 146 ? 137.991 156.161 138.695 1.00 220.90 ?  146  TYR A CD2 1 
ATOM   237  C CE1 . TYR A 1 146 ? 138.031 158.884 139.058 1.00 220.90 ?  146  TYR A CE1 1 
ATOM   238  C CE2 . TYR A 1 146 ? 136.882 156.906 138.381 1.00 220.90 ?  146  TYR A CE2 1 
ATOM   239  C CZ  . TYR A 1 146 ? 136.907 158.263 138.563 1.00 220.90 ?  146  TYR A CZ  1 
ATOM   240  O OH  . TYR A 1 146 ? 135.791 158.983 138.235 1.00 220.90 ?  146  TYR A OH  1 
ATOM   241  N N   . LYS A 1 147 ? 140.416 155.424 142.487 1.00 198.72 ?  147  LYS A N   1 
ATOM   242  C CA  . LYS A 1 147 ? 139.815 155.430 143.810 1.00 198.72 ?  147  LYS A CA  1 
ATOM   243  C C   . LYS A 1 147 ? 140.755 155.979 144.861 1.00 198.72 ?  147  LYS A C   1 
ATOM   244  O O   . LYS A 1 147 ? 140.334 156.722 145.738 1.00 198.72 ?  147  LYS A O   1 
ATOM   245  C CB  . LYS A 1 147 ? 139.372 154.022 144.195 1.00 198.72 ?  147  LYS A CB  1 
ATOM   246  C CG  . LYS A 1 147 ? 137.951 153.693 143.782 1.00 198.72 ?  147  LYS A CG  1 
ATOM   247  C CD  . LYS A 1 147 ? 137.879 152.335 143.108 1.00 198.72 ?  147  LYS A CD  1 
ATOM   248  C CE  . LYS A 1 147 ? 136.871 152.354 141.975 1.00 198.72 ?  147  LYS A CE  1 
ATOM   249  N NZ  . LYS A 1 147 ? 135.591 152.973 142.419 1.00 198.72 1  147  LYS A NZ  1 
ATOM   250  N N   . TRP A 1 148 ? 142.029 155.620 144.778 1.00 237.89 ?  148  TRP A N   1 
ATOM   251  C CA  . TRP A 1 148 ? 143.007 156.112 145.733 1.00 237.89 ?  148  TRP A CA  1 
ATOM   252  C C   . TRP A 1 148 ? 143.148 157.616 145.637 1.00 237.89 ?  148  TRP A C   1 
ATOM   253  O O   . TRP A 1 148 ? 143.125 158.290 146.645 1.00 237.89 ?  148  TRP A O   1 
ATOM   254  C CB  . TRP A 1 148 ? 144.366 155.443 145.528 1.00 237.89 ?  148  TRP A CB  1 
ATOM   255  C CG  . TRP A 1 148 ? 145.493 156.190 146.165 1.00 237.89 ?  148  TRP A CG  1 
ATOM   256  C CD1 . TRP A 1 148 ? 145.770 156.276 147.499 1.00 237.89 ?  148  TRP A CD1 1 
ATOM   257  C CD2 . TRP A 1 148 ? 146.487 156.973 145.498 1.00 237.89 ?  148  TRP A CD2 1 
ATOM   258  N NE1 . TRP A 1 148 ? 146.875 157.062 147.701 1.00 237.89 ?  148  TRP A NE1 1 
ATOM   259  C CE2 . TRP A 1 148 ? 147.334 157.503 146.489 1.00 237.89 ?  148  TRP A CE2 1 
ATOM   260  C CE3 . TRP A 1 148 ? 146.743 157.276 144.159 1.00 237.89 ?  148  TRP A CE3 1 
ATOM   261  C CZ2 . TRP A 1 148 ? 148.420 158.315 146.182 1.00 237.89 ?  148  TRP A CZ2 1 
ATOM   262  C CZ3 . TRP A 1 148 ? 147.816 158.085 143.857 1.00 237.89 ?  148  TRP A CZ3 1 
ATOM   263  C CH2 . TRP A 1 148 ? 148.645 158.592 144.863 1.00 237.89 ?  148  TRP A CH2 1 
ATOM   264  N N   . SER A 1 149 ? 143.289 158.146 144.429 1.00 206.54 ?  149  SER A N   1 
ATOM   265  C CA  . SER A 1 149 ? 143.450 159.578 144.244 1.00 206.54 ?  149  SER A CA  1 
ATOM   266  C C   . SER A 1 149 ? 142.238 160.314 144.749 1.00 206.54 ?  149  SER A C   1 
ATOM   267  O O   . SER A 1 149 ? 142.354 161.377 145.343 1.00 206.54 ?  149  SER A O   1 
ATOM   268  C CB  . SER A 1 149 ? 143.657 159.911 142.771 1.00 206.54 ?  149  SER A CB  1 
ATOM   269  O OG  . SER A 1 149 ? 144.790 159.250 142.243 1.00 206.54 ?  149  SER A OG  1 
ATOM   270  N N   . TYR A 1 150 ? 141.064 159.747 144.518 1.00 168.90 ?  150  TYR A N   1 
ATOM   271  C CA  . TYR A 1 150 ? 139.838 160.372 144.961 1.00 168.90 ?  150  TYR A CA  1 
ATOM   272  C C   . TYR A 1 150 ? 139.772 160.410 146.478 1.00 168.90 ?  150  TYR A C   1 
ATOM   273  O O   . TYR A 1 150 ? 139.283 161.375 147.056 1.00 168.90 ?  150  TYR A O   1 
ATOM   274  C CB  . TYR A 1 150 ? 138.655 159.608 144.384 1.00 168.90 ?  150  TYR A CB  1 
ATOM   275  C CG  . TYR A 1 150 ? 137.326 160.172 144.767 1.00 168.90 ?  150  TYR A CG  1 
ATOM   276  C CD1 . TYR A 1 150 ? 136.904 161.390 144.266 1.00 168.90 ?  150  TYR A CD1 1 
ATOM   277  C CD2 . TYR A 1 150 ? 136.491 159.490 145.637 1.00 168.90 ?  150  TYR A CD2 1 
ATOM   278  C CE1 . TYR A 1 150 ? 135.680 161.908 144.613 1.00 168.90 ?  150  TYR A CE1 1 
ATOM   279  C CE2 . TYR A 1 150 ? 135.273 160.007 145.996 1.00 168.90 ?  150  TYR A CE2 1 
ATOM   280  C CZ  . TYR A 1 150 ? 134.878 161.215 145.479 1.00 168.90 ?  150  TYR A CZ  1 
ATOM   281  O OH  . TYR A 1 150 ? 133.673 161.730 145.838 1.00 168.90 ?  150  TYR A OH  1 
ATOM   282  N N   . ALA A 1 151 ? 140.263 159.363 147.128 1.00 187.55 ?  151  ALA A N   1 
ATOM   283  C CA  . ALA A 1 151 ? 140.241 159.305 148.581 1.00 187.55 ?  151  ALA A CA  1 
ATOM   284  C C   . ALA A 1 151 ? 141.381 160.111 149.167 1.00 187.55 ?  151  ALA A C   1 
ATOM   285  O O   . ALA A 1 151 ? 141.276 160.609 150.285 1.00 187.55 ?  151  ALA A O   1 
ATOM   286  C CB  . ALA A 1 151 ? 140.324 157.866 149.046 1.00 187.55 ?  151  ALA A CB  1 
ATOM   287  N N   . GLN A 1 152 ? 142.412 160.376 148.379 1.00 228.04 ?  152  GLN A N   1 
ATOM   288  C CA  . GLN A 1 152 ? 143.490 161.236 148.852 1.00 228.04 ?  152  GLN A CA  1 
ATOM   289  C C   . GLN A 1 152 ? 143.038 162.692 148.906 1.00 228.04 ?  152  GLN A C   1 
ATOM   290  O O   . GLN A 1 152 ? 143.677 163.518 149.553 1.00 228.04 ?  152  GLN A O   1 
ATOM   291  C CB  . GLN A 1 152 ? 144.724 161.087 147.963 1.00 228.04 ?  152  GLN A CB  1 
ATOM   292  C CG  . GLN A 1 152 ? 145.910 160.407 148.631 1.00 228.04 ?  152  GLN A CG  1 
ATOM   293  C CD  . GLN A 1 152 ? 145.514 159.493 149.778 1.00 228.04 ?  152  GLN A CD  1 
ATOM   294  O OE1 . GLN A 1 152 ? 144.882 158.456 149.576 1.00 228.04 ?  152  GLN A OE1 1 
ATOM   295  N NE2 . GLN A 1 152 ? 145.902 159.868 150.991 1.00 228.04 ?  152  GLN A NE2 1 
ATOM   296  N N   . MET A 1 153 ? 141.934 163.009 148.238 1.00 256.85 ?  153  MET A N   1 
ATOM   297  C CA  . MET A 1 153 ? 141.421 164.380 148.232 1.00 256.85 ?  153  MET A CA  1 
ATOM   298  C C   . MET A 1 153 ? 140.231 164.511 149.159 1.00 256.85 ?  153  MET A C   1 
ATOM   299  O O   . MET A 1 153 ? 139.522 165.510 149.101 1.00 256.85 ?  153  MET A O   1 
ATOM   300  C CB  . MET A 1 153 ? 141.006 164.792 146.821 1.00 256.85 ?  153  MET A CB  1 
ATOM   301  C CG  . MET A 1 153 ? 142.079 164.612 145.766 1.00 256.85 ?  153  MET A CG  1 
ATOM   302  S SD  . MET A 1 153 ? 143.542 165.615 146.070 1.00 256.85 ?  153  MET A SD  1 
ATOM   303  C CE  . MET A 1 153 ? 143.819 166.301 144.440 1.00 256.85 ?  153  MET A CE  1 
ATOM   304  N N   . GLN A 1 154 ? 140.024 163.531 150.031 1.00 267.26 ?  154  GLN A N   1 
ATOM   305  C CA  . GLN A 1 154 ? 138.852 163.514 150.919 1.00 267.26 ?  154  GLN A CA  1 
ATOM   306  C C   . GLN A 1 154 ? 138.226 164.826 151.409 1.00 267.26 ?  154  GLN A C   1 
ATOM   307  O O   . GLN A 1 154 ? 137.068 165.098 151.095 1.00 267.26 ?  154  GLN A O   1 
ATOM   308  C CB  . GLN A 1 154 ? 139.070 162.540 152.087 1.00 267.26 ?  154  GLN A CB  1 
ATOM   309  C CG  . GLN A 1 154 ? 137.792 161.906 152.612 1.00 267.26 ?  154  GLN A CG  1 
ATOM   310  C CD  . GLN A 1 154 ? 136.985 161.229 151.523 1.00 267.26 ?  154  GLN A CD  1 
ATOM   311  O OE1 . GLN A 1 154 ? 137.466 160.313 150.855 1.00 267.26 ?  154  GLN A OE1 1 
ATOM   312  N NE2 . GLN A 1 154 ? 135.747 161.675 151.339 1.00 267.26 ?  154  GLN A NE2 1 
ATOM   313  N N   . PRO A 1 155 ? 138.965 165.641 152.183 1.00 242.74 ?  155  PRO A N   1 
ATOM   314  C CA  . PRO A 1 155 ? 138.284 166.835 152.706 1.00 242.74 ?  155  PRO A CA  1 
ATOM   315  C C   . PRO A 1 155 ? 137.778 167.794 151.637 1.00 242.74 ?  155  PRO A C   1 
ATOM   316  O O   . PRO A 1 155 ? 136.597 168.138 151.655 1.00 242.74 ?  155  PRO A O   1 
ATOM   317  C CB  . PRO A 1 155 ? 139.369 167.524 153.545 1.00 242.74 ?  155  PRO A CB  1 
ATOM   318  C CG  . PRO A 1 155 ? 140.408 166.481 153.788 1.00 242.74 ?  155  PRO A CG  1 
ATOM   319  C CD  . PRO A 1 155 ? 140.388 165.622 152.564 1.00 242.74 ?  155  PRO A CD  1 
ATOM   320  N N   . SER A 1 156 ? 138.640 168.222 150.723 1.00 232.47 ?  156  SER A N   1 
ATOM   321  C CA  . SER A 1 156 ? 138.241 169.212 149.728 1.00 232.47 ?  156  SER A CA  1 
ATOM   322  C C   . SER A 1 156 ? 137.324 168.672 148.653 1.00 232.47 ?  156  SER A C   1 
ATOM   323  O O   . SER A 1 156 ? 137.712 167.800 147.889 1.00 232.47 ?  156  SER A O   1 
ATOM   324  C CB  . SER A 1 156 ? 139.474 169.836 149.083 1.00 232.47 ?  156  SER A CB  1 
ATOM   325  O OG  . SER A 1 156 ? 139.111 170.878 148.198 1.00 232.47 ?  156  SER A OG  1 
ATOM   326  N N   . LEU A 1 157 ? 136.113 169.208 148.577 1.00 209.06 ?  157  LEU A N   1 
ATOM   327  C CA  . LEU A 1 157 ? 135.164 168.782 147.551 1.00 209.06 ?  157  LEU A CA  1 
ATOM   328  C C   . LEU A 1 157 ? 135.526 169.202 146.119 1.00 209.06 ?  157  LEU A C   1 
ATOM   329  O O   . LEU A 1 157 ? 135.373 168.405 145.200 1.00 209.06 ?  157  LEU A O   1 
ATOM   330  C CB  . LEU A 1 157 ? 133.740 169.224 147.909 1.00 209.06 ?  157  LEU A CB  1 
ATOM   331  C CG  . LEU A 1 157 ? 132.739 168.118 148.242 1.00 209.06 ?  157  LEU A CG  1 
ATOM   332  C CD1 . LEU A 1 157 ? 131.585 168.128 147.253 1.00 209.06 ?  157  LEU A CD1 1 
ATOM   333  C CD2 . LEU A 1 157 ? 133.422 166.760 148.261 1.00 209.06 ?  157  LEU A CD2 1 
ATOM   334  N N   . PRO A 1 158 ? 135.985 170.453 145.909 1.00 201.91 ?  158  PRO A N   1 
ATOM   335  C CA  . PRO A 1 158 ? 136.395 170.770 144.533 1.00 201.91 ?  158  PRO A CA  1 
ATOM   336  C C   . PRO A 1 158 ? 137.543 169.893 144.051 1.00 201.91 ?  158  PRO A C   1 
ATOM   337  O O   . PRO A 1 158 ? 137.581 169.551 142.875 1.00 201.91 ?  158  PRO A O   1 
ATOM   338  C CB  . PRO A 1 158 ? 136.846 172.235 144.623 1.00 201.91 ?  158  PRO A CB  1 
ATOM   339  C CG  . PRO A 1 158 ? 136.936 172.554 146.077 1.00 201.91 ?  158  PRO A CG  1 
ATOM   340  C CD  . PRO A 1 158 ? 135.931 171.669 146.737 1.00 201.91 ?  158  PRO A CD  1 
ATOM   341  N N   . LEU A 1 159 ? 138.466 169.543 144.935 1.00 219.69 ?  159  LEU A N   1 
ATOM   342  C CA  . LEU A 1 159 ? 139.575 168.675 144.582 1.00 219.69 ?  159  LEU A CA  1 
ATOM   343  C C   . LEU A 1 159 ? 139.077 167.278 144.295 1.00 219.69 ?  159  LEU A C   1 
ATOM   344  O O   . LEU A 1 159 ? 139.580 166.609 143.397 1.00 219.69 ?  159  LEU A O   1 
ATOM   345  C CB  . LEU A 1 159 ? 140.597 168.647 145.705 1.00 219.69 ?  159  LEU A CB  1 
ATOM   346  C CG  . LEU A 1 159 ? 141.554 169.833 145.710 1.00 219.69 ?  159  LEU A CG  1 
ATOM   347  C CD1 . LEU A 1 159 ? 142.672 169.607 146.713 1.00 219.69 ?  159  LEU A CD1 1 
ATOM   348  C CD2 . LEU A 1 159 ? 142.111 170.061 144.315 1.00 219.69 ?  159  LEU A CD2 1 
ATOM   349  N N   . GLN A 1 160 ? 138.086 166.828 145.053 1.00 190.31 ?  160  GLN A N   1 
ATOM   350  C CA  . GLN A 1 160 ? 137.504 165.523 144.803 1.00 190.31 ?  160  GLN A CA  1 
ATOM   351  C C   . GLN A 1 160 ? 136.872 165.530 143.431 1.00 190.31 ?  160  GLN A C   1 
ATOM   352  O O   . GLN A 1 160 ? 137.050 164.592 142.667 1.00 190.31 ?  160  GLN A O   1 
ATOM   353  C CB  . GLN A 1 160 ? 136.463 165.198 145.865 1.00 190.31 ?  160  GLN A CB  1 
ATOM   354  C CG  . GLN A 1 160 ? 137.063 164.762 147.188 1.00 190.31 ?  160  GLN A CG  1 
ATOM   355  C CD  . GLN A 1 160 ? 136.258 163.677 147.865 1.00 190.31 ?  160  GLN A CD  1 
ATOM   356  O OE1 . GLN A 1 160 ? 135.031 163.727 147.895 1.00 190.31 ?  160  GLN A OE1 1 
ATOM   357  N NE2 . GLN A 1 160 ? 136.947 162.684 148.412 1.00 190.31 ?  160  GLN A NE2 1 
ATOM   358  N N   . PHE A 1 161 ? 136.153 166.599 143.106 1.00 210.02 ?  161  PHE A N   1 
ATOM   359  C CA  . PHE A 1 161 ? 135.529 166.719 141.797 1.00 210.02 ?  161  PHE A CA  1 
ATOM   360  C C   . PHE A 1 161 ? 136.566 166.669 140.713 1.00 210.02 ?  161  PHE A C   1 
ATOM   361  O O   . PHE A 1 161 ? 136.383 165.973 139.728 1.00 210.02 ?  161  PHE A O   1 
ATOM   362  C CB  . PHE A 1 161 ? 134.737 168.017 141.690 1.00 210.02 ?  161  PHE A CB  1 
ATOM   363  C CG  . PHE A 1 161 ? 133.888 168.110 140.459 1.00 210.02 ?  161  PHE A CG  1 
ATOM   364  C CD1 . PHE A 1 161 ? 132.749 167.340 140.335 1.00 210.02 ?  161  PHE A CD1 1 
ATOM   365  C CD2 . PHE A 1 161 ? 134.230 168.965 139.426 1.00 210.02 ?  161  PHE A CD2 1 
ATOM   366  C CE1 . PHE A 1 161 ? 131.960 167.421 139.208 1.00 210.02 ?  161  PHE A CE1 1 
ATOM   367  C CE2 . PHE A 1 161 ? 133.448 169.050 138.293 1.00 210.02 ?  161  PHE A CE2 1 
ATOM   368  C CZ  . PHE A 1 161 ? 132.309 168.278 138.184 1.00 210.02 ?  161  PHE A CZ  1 
ATOM   369  N N   . LEU A 1 162 ? 137.652 167.408 140.895 1.00 201.58 ?  162  LEU A N   1 
ATOM   370  C CA  . LEU A 1 162 ? 138.717 167.422 139.911 1.00 201.58 ?  162  LEU A CA  1 
ATOM   371  C C   . LEU A 1 162 ? 139.176 166.015 139.581 1.00 201.58 ?  162  LEU A C   1 
ATOM   372  O O   . LEU A 1 162 ? 139.106 165.609 138.442 1.00 201.58 ?  162  LEU A O   1 
ATOM   373  C CB  . LEU A 1 162 ? 139.891 168.255 140.402 1.00 201.58 ?  162  LEU A CB  1 
ATOM   374  C CG  . LEU A 1 162 ? 140.156 169.546 139.633 1.00 201.58 ?  162  LEU A CG  1 
ATOM   375  C CD1 . LEU A 1 162 ? 139.138 169.722 138.518 1.00 201.58 ?  162  LEU A CD1 1 
ATOM   376  C CD2 . LEU A 1 162 ? 140.133 170.736 140.578 1.00 201.58 ?  162  LEU A CD2 1 
ATOM   377  N N   . VAL A 1 163 ? 139.619 165.262 140.578 1.00 217.21 ?  163  VAL A N   1 
ATOM   378  C CA  . VAL A 1 163 ? 140.036 163.886 140.339 1.00 217.21 ?  163  VAL A CA  1 
ATOM   379  C C   . VAL A 1 163 ? 138.932 163.077 139.682 1.00 217.21 ?  163  VAL A C   1 
ATOM   380  O O   . VAL A 1 163 ? 139.151 162.445 138.649 1.00 217.21 ?  163  VAL A O   1 
ATOM   381  C CB  . VAL A 1 163 ? 140.497 163.198 141.635 1.00 217.21 ?  163  VAL A CB  1 
ATOM   382  C CG1 . VAL A 1 163 ? 140.580 161.691 141.447 1.00 217.21 ?  163  VAL A CG1 1 
ATOM   383  C CG2 . VAL A 1 163 ? 141.858 163.735 142.038 1.00 217.21 ?  163  VAL A CG2 1 
ATOM   384  N N   . TRP A 1 164 ? 137.729 163.132 140.241 1.00 191.84 ?  164  TRP A N   1 
ATOM   385  C CA  . TRP A 1 164 ? 136.635 162.336 139.708 1.00 191.84 ?  164  TRP A CA  1 
ATOM   386  C C   . TRP A 1 164 ? 136.312 162.603 138.238 1.00 191.84 ?  164  TRP A C   1 
ATOM   387  O O   . TRP A 1 164 ? 135.856 161.712 137.541 1.00 191.84 ?  164  TRP A O   1 
ATOM   388  C CB  . TRP A 1 164 ? 135.378 162.471 140.568 1.00 191.84 ?  164  TRP A CB  1 
ATOM   389  C CG  . TRP A 1 164 ? 134.421 161.352 140.352 1.00 191.84 ?  164  TRP A CG  1 
ATOM   390  C CD1 . TRP A 1 164 ? 133.321 161.368 139.559 1.00 191.84 ?  164  TRP A CD1 1 
ATOM   391  C CD2 . TRP A 1 164 ? 134.496 160.036 140.907 1.00 191.84 ?  164  TRP A CD2 1 
ATOM   392  N NE1 . TRP A 1 164 ? 132.697 160.150 139.585 1.00 191.84 ?  164  TRP A NE1 1 
ATOM   393  C CE2 . TRP A 1 164 ? 133.399 159.312 140.408 1.00 191.84 ?  164  TRP A CE2 1 
ATOM   394  C CE3 . TRP A 1 164 ? 135.385 159.397 141.772 1.00 191.84 ?  164  TRP A CE3 1 
ATOM   395  C CZ2 . TRP A 1 164 ? 133.164 157.989 140.752 1.00 191.84 ?  164  TRP A CZ2 1 
ATOM   396  C CZ3 . TRP A 1 164 ? 135.150 158.086 142.112 1.00 191.84 ?  164  TRP A CZ3 1 
ATOM   397  C CH2 . TRP A 1 164 ? 134.048 157.394 141.604 1.00 191.84 ?  164  TRP A CH2 1 
ATOM   398  N N   . VAL A 1 165 ? 136.535 163.815 137.755 1.00 211.85 ?  165  VAL A N   1 
ATOM   399  C CA  . VAL A 1 165 ? 136.278 164.069 136.354 1.00 211.85 ?  165  VAL A CA  1 
ATOM   400  C C   . VAL A 1 165 ? 137.512 164.007 135.468 1.00 211.85 ?  165  VAL A C   1 
ATOM   401  O O   . VAL A 1 165 ? 137.409 163.566 134.337 1.00 211.85 ?  165  VAL A O   1 
ATOM   402  C CB  . VAL A 1 165 ? 135.465 165.363 136.113 1.00 211.85 ?  165  VAL A CB  1 
ATOM   403  C CG1 . VAL A 1 165 ? 134.160 165.315 136.885 1.00 211.85 ?  165  VAL A CG1 1 
ATOM   404  C CG2 . VAL A 1 165 ? 136.259 166.613 136.460 1.00 211.85 ?  165  VAL A CG2 1 
ATOM   405  N N   . THR A 1 166 ? 138.678 164.395 135.970 1.00 246.51 ?  166  THR A N   1 
ATOM   406  C CA  . THR A 1 166 ? 139.864 164.442 135.119 1.00 246.51 ?  166  THR A CA  1 
ATOM   407  C C   . THR A 1 166 ? 140.490 163.095 134.881 1.00 246.51 ?  166  THR A C   1 
ATOM   408  O O   . THR A 1 166 ? 140.955 162.839 133.793 1.00 246.51 ?  166  THR A O   1 
ATOM   409  C CB  . THR A 1 166 ? 140.955 165.400 135.638 1.00 246.51 ?  166  THR A CB  1 
ATOM   410  O OG1 . THR A 1 166 ? 141.350 165.018 136.960 1.00 246.51 ?  166  THR A OG1 1 
ATOM   411  C CG2 . THR A 1 166 ? 140.454 166.837 135.633 1.00 246.51 ?  166  THR A CG2 1 
ATOM   412  N N   . PHE A 1 167 ? 140.527 162.238 135.888 1.00 237.22 ?  167  PHE A N   1 
ATOM   413  C CA  . PHE A 1 167 ? 141.038 160.889 135.675 1.00 237.22 ?  167  PHE A CA  1 
ATOM   414  C C   . PHE A 1 167 ? 140.341 160.219 134.482 1.00 237.22 ?  167  PHE A C   1 
ATOM   415  O O   . PHE A 1 167 ? 141.018 159.801 133.540 1.00 237.22 ?  167  PHE A O   1 
ATOM   416  C CB  . PHE A 1 167 ? 140.978 160.071 136.970 1.00 237.22 ?  167  PHE A CB  1 
ATOM   417  C CG  . PHE A 1 167 ? 141.968 158.950 137.043 1.00 237.22 ?  167  PHE A CG  1 
ATOM   418  C CD1 . PHE A 1 167 ? 141.752 157.766 136.361 1.00 237.22 ?  167  PHE A CD1 1 
ATOM   419  C CD2 . PHE A 1 167 ? 143.099 159.067 137.830 1.00 237.22 ?  167  PHE A CD2 1 
ATOM   420  C CE1 . PHE A 1 167 ? 142.659 156.734 136.440 1.00 237.22 ?  167  PHE A CE1 1 
ATOM   421  C CE2 . PHE A 1 167 ? 144.009 158.036 137.914 1.00 237.22 ?  167  PHE A CE2 1 
ATOM   422  C CZ  . PHE A 1 167 ? 143.791 156.867 137.216 1.00 237.22 ?  167  PHE A CZ  1 
ATOM   423  N N   . PRO A 1 168 ? 138.989 160.133 134.484 1.00 249.60 ?  168  PRO A N   1 
ATOM   424  C CA  . PRO A 1 168 ? 138.390 159.560 133.276 1.00 249.60 ?  168  PRO A CA  1 
ATOM   425  C C   . PRO A 1 168 ? 138.634 160.399 132.031 1.00 249.60 ?  168  PRO A C   1 
ATOM   426  O O   . PRO A 1 168 ? 138.879 159.826 130.985 1.00 249.60 ?  168  PRO A O   1 
ATOM   427  C CB  . PRO A 1 168 ? 136.904 159.560 133.599 1.00 249.60 ?  168  PRO A CB  1 
ATOM   428  C CG  . PRO A 1 168 ? 136.840 159.464 135.062 1.00 249.60 ?  168  PRO A CG  1 
ATOM   429  C CD  . PRO A 1 168 ? 137.961 160.331 135.520 1.00 249.60 ?  168  PRO A CD  1 
ATOM   430  N N   . LEU A 1 169 ? 138.559 161.722 132.134 1.00 300.80 ?  169  LEU A N   1 
ATOM   431  C CA  . LEU A 1 169 ? 138.742 162.584 130.979 1.00 300.80 ?  169  LEU A CA  1 
ATOM   432  C C   . LEU A 1 169 ? 140.066 162.325 130.309 1.00 300.80 ?  169  LEU A C   1 
ATOM   433  O O   . LEU A 1 169 ? 140.108 162.114 129.113 1.00 300.80 ?  169  LEU A O   1 
ATOM   434  C CB  . LEU A 1 169 ? 138.652 164.054 131.368 1.00 300.80 ?  169  LEU A CB  1 
ATOM   435  C CG  . LEU A 1 169 ? 137.365 164.784 131.002 1.00 300.80 ?  169  LEU A CG  1 
ATOM   436  C CD1 . LEU A 1 169 ? 137.154 165.980 131.915 1.00 300.80 ?  169  LEU A CD1 1 
ATOM   437  C CD2 . LEU A 1 169 ? 137.462 165.238 129.563 1.00 300.80 ?  169  LEU A CD2 1 
ATOM   438  N N   . VAL A 1 170 ? 141.145 162.327 131.077 1.00 303.99 ?  170  VAL A N   1 
ATOM   439  C CA  . VAL A 1 170 ? 142.467 162.090 130.524 1.00 303.99 ?  170  VAL A CA  1 
ATOM   440  C C   . VAL A 1 170 ? 142.502 160.742 129.838 1.00 303.99 ?  170  VAL A C   1 
ATOM   441  O O   . VAL A 1 170 ? 142.937 160.641 128.702 1.00 303.99 ?  170  VAL A O   1 
ATOM   442  C CB  . VAL A 1 170 ? 143.556 162.179 131.615 1.00 303.99 ?  170  VAL A CB  1 
ATOM   443  C CG1 . VAL A 1 170 ? 144.876 161.586 131.146 1.00 303.99 ?  170  VAL A CG1 1 
ATOM   444  C CG2 . VAL A 1 170 ? 143.753 163.626 132.037 1.00 303.99 ?  170  VAL A CG2 1 
ATOM   445  N N   . LEU A 1 171 ? 141.999 159.711 130.500 1.00 296.97 ?  171  LEU A N   1 
ATOM   446  C CA  . LEU A 1 171 ? 142.049 158.373 129.933 1.00 296.97 ?  171  LEU A CA  1 
ATOM   447  C C   . LEU A 1 171 ? 141.228 158.204 128.663 1.00 296.97 ?  171  LEU A C   1 
ATOM   448  O O   . LEU A 1 171 ? 141.664 157.544 127.734 1.00 296.97 ?  171  LEU A O   1 
ATOM   449  C CB  . LEU A 1 171 ? 141.628 157.356 130.980 1.00 296.97 ?  171  LEU A CB  1 
ATOM   450  C CG  . LEU A 1 171 ? 142.726 157.079 131.998 1.00 296.97 ?  171  LEU A CG  1 
ATOM   451  C CD1 . LEU A 1 171 ? 142.387 155.821 132.762 1.00 296.97 ?  171  LEU A CD1 1 
ATOM   452  C CD2 . LEU A 1 171 ? 144.069 156.934 131.302 1.00 296.97 ?  171  LEU A CD2 1 
ATOM   453  N N   . ILE A 1 172 ? 140.052 158.810 128.612 1.00 290.81 ?  172  ILE A N   1 
ATOM   454  C CA  . ILE A 1 172 ? 139.207 158.712 127.431 1.00 290.81 ?  172  ILE A CA  1 
ATOM   455  C C   . ILE A 1 172 ? 139.760 159.582 126.313 1.00 290.81 ?  172  ILE A C   1 
ATOM   456  O O   . ILE A 1 172 ? 139.750 159.195 125.150 1.00 290.81 ?  172  ILE A O   1 
ATOM   457  C CB  . ILE A 1 172 ? 137.745 159.075 127.754 1.00 290.81 ?  172  ILE A CB  1 
ATOM   458  C CG1 . ILE A 1 172 ? 137.150 158.051 128.718 1.00 290.81 ?  172  ILE A CG1 1 
ATOM   459  C CG2 . ILE A 1 172 ? 136.897 159.125 126.497 1.00 290.81 ?  172  ILE A CG2 1 
ATOM   460  C CD1 . ILE A 1 172 ? 136.982 156.676 128.117 1.00 290.81 ?  172  ILE A CD1 1 
ATOM   461  N N   . LEU A 1 173 ? 140.285 160.746 126.661 1.00 334.45 ?  173  LEU A N   1 
ATOM   462  C CA  . LEU A 1 173 ? 140.886 161.601 125.650 1.00 334.45 ?  173  LEU A CA  1 
ATOM   463  C C   . LEU A 1 173 ? 142.092 160.902 125.080 1.00 334.45 ?  173  LEU A C   1 
ATOM   464  O O   . LEU A 1 173 ? 142.320 160.960 123.882 1.00 334.45 ?  173  LEU A O   1 
ATOM   465  C CB  . LEU A 1 173 ? 141.285 162.949 126.231 1.00 334.45 ?  173  LEU A CB  1 
ATOM   466  C CG  . LEU A 1 173 ? 140.426 164.134 125.794 1.00 334.45 ?  173  LEU A CG  1 
ATOM   467  C CD1 . LEU A 1 173 ? 139.057 163.669 125.336 1.00 334.45 ?  173  LEU A CD1 1 
ATOM   468  C CD2 . LEU A 1 173 ? 140.308 165.146 126.918 1.00 334.45 ?  173  LEU A CD2 1 
ATOM   469  N N   . PHE A 1 174 ? 142.862 160.229 125.925 1.00 322.85 ?  174  PHE A N   1 
ATOM   470  C CA  . PHE A 1 174 ? 143.996 159.463 125.443 1.00 322.85 ?  174  PHE A CA  1 
ATOM   471  C C   . PHE A 1 174 ? 143.507 158.368 124.516 1.00 322.85 ?  174  PHE A C   1 
ATOM   472  O O   . PHE A 1 174 ? 144.045 158.203 123.445 1.00 322.85 ?  174  PHE A O   1 
ATOM   473  C CB  . PHE A 1 174 ? 144.785 158.860 126.602 1.00 322.85 ?  174  PHE A CB  1 
ATOM   474  C CG  . PHE A 1 174 ? 145.791 157.832 126.182 1.00 322.85 ?  174  PHE A CG  1 
ATOM   475  C CD1 . PHE A 1 174 ? 146.942 158.206 125.511 1.00 322.85 ?  174  PHE A CD1 1 
ATOM   476  C CD2 . PHE A 1 174 ? 145.586 156.491 126.456 1.00 322.85 ?  174  PHE A CD2 1 
ATOM   477  C CE1 . PHE A 1 174 ? 147.868 157.263 125.119 1.00 322.85 ?  174  PHE A CE1 1 
ATOM   478  C CE2 . PHE A 1 174 ? 146.504 155.544 126.062 1.00 322.85 ?  174  PHE A CE2 1 
ATOM   479  C CZ  . PHE A 1 174 ? 147.649 155.931 125.395 1.00 322.85 ?  174  PHE A CZ  1 
ATOM   480  N N   . SER A 1 175 ? 142.485 157.625 124.925 1.00 290.57 ?  175  SER A N   1 
ATOM   481  C CA  . SER A 1 175 ? 141.935 156.570 124.085 1.00 290.57 ?  175  SER A CA  1 
ATOM   482  C C   . SER A 1 175 ? 141.608 157.094 122.706 1.00 290.57 ?  175  SER A C   1 
ATOM   483  O O   . SER A 1 175 ? 142.062 156.545 121.707 1.00 290.57 ?  175  SER A O   1 
ATOM   484  C CB  . SER A 1 175 ? 140.674 155.979 124.708 1.00 290.57 ?  175  SER A CB  1 
ATOM   485  O OG  . SER A 1 175 ? 140.921 155.449 125.991 1.00 290.57 ?  175  SER A OG  1 
ATOM   486  N N   . ALA A 1 176 ? 140.831 158.167 122.644 1.00 295.67 ?  176  ALA A N   1 
ATOM   487  C CA  . ALA A 1 176 ? 140.441 158.737 121.368 1.00 295.67 ?  176  ALA A CA  1 
ATOM   488  C C   . ALA A 1 176 ? 141.636 159.227 120.567 1.00 295.67 ?  176  ALA A C   1 
ATOM   489  O O   . ALA A 1 176 ? 141.742 158.942 119.382 1.00 295.67 ?  176  ALA A O   1 
ATOM   490  C CB  . ALA A 1 176 ? 139.445 159.858 121.584 1.00 295.67 ?  176  ALA A CB  1 
ATOM   491  N N   . LEU A 1 177 ? 142.542 159.952 121.210 1.00 323.50 ?  177  LEU A N   1 
ATOM   492  C CA  . LEU A 1 177 ? 143.719 160.464 120.520 1.00 323.50 ?  177  LEU A CA  1 
ATOM   493  C C   . LEU A 1 177 ? 144.626 159.354 120.023 1.00 323.50 ?  177  LEU A C   1 
ATOM   494  O O   . LEU A 1 177 ? 145.049 159.377 118.879 1.00 323.50 ?  177  LEU A O   1 
ATOM   495  C CB  . LEU A 1 177 ? 144.510 161.408 121.420 1.00 323.50 ?  177  LEU A CB  1 
ATOM   496  C CG  . LEU A 1 177 ? 145.360 162.447 120.694 1.00 323.50 ?  177  LEU A CG  1 
ATOM   497  C CD1 . LEU A 1 177 ? 144.568 163.112 119.579 1.00 323.50 ?  177  LEU A CD1 1 
ATOM   498  C CD2 . LEU A 1 177 ? 145.889 163.475 121.677 1.00 323.50 ?  177  LEU A CD2 1 
ATOM   499  N N   . PHE A 1 178 ? 144.929 158.387 120.878 1.00 305.78 ?  178  PHE A N   1 
ATOM   500  C CA  . PHE A 1 178 ? 145.790 157.280 120.493 1.00 305.78 ?  178  PHE A CA  1 
ATOM   501  C C   . PHE A 1 178 ? 145.223 156.602 119.274 1.00 305.78 ?  178  PHE A C   1 
ATOM   502  O O   . PHE A 1 178 ? 145.945 156.324 118.333 1.00 305.78 ?  178  PHE A O   1 
ATOM   503  C CB  . PHE A 1 178 ? 145.899 156.266 121.624 1.00 305.78 ?  178  PHE A CB  1 
ATOM   504  C CG  . PHE A 1 178 ? 147.044 155.316 121.477 1.00 305.78 ?  178  PHE A CG  1 
ATOM   505  C CD1 . PHE A 1 178 ? 148.344 155.753 121.642 1.00 305.78 ?  178  PHE A CD1 1 
ATOM   506  C CD2 . PHE A 1 178 ? 146.821 153.987 121.176 1.00 305.78 ?  178  PHE A CD2 1 
ATOM   507  C CE1 . PHE A 1 178 ? 149.403 154.881 121.511 1.00 305.78 ?  178  PHE A CE1 1 
ATOM   508  C CE2 . PHE A 1 178 ? 147.876 153.112 121.036 1.00 305.78 ?  178  PHE A CE2 1 
ATOM   509  C CZ  . PHE A 1 178 ? 149.169 153.556 121.208 1.00 305.78 ?  178  PHE A CZ  1 
ATOM   510  N N   . CYS A 1 179 ? 143.925 156.334 119.288 1.00 247.55 ?  179  CYS A N   1 
ATOM   511  C CA  . CYS A 1 179 ? 143.288 155.731 118.135 1.00 247.55 ?  179  CYS A CA  1 
ATOM   512  C C   . CYS A 1 179 ? 143.486 156.600 116.912 1.00 247.55 ?  179  CYS A C   1 
ATOM   513  O O   . CYS A 1 179 ? 144.107 156.178 115.956 1.00 247.55 ?  179  CYS A O   1 
ATOM   514  C CB  . CYS A 1 179 ? 141.811 155.510 118.406 1.00 247.55 ?  179  CYS A CB  1 
ATOM   515  S SG  . CYS A 1 179 ? 141.459 153.856 119.014 1.00 247.55 ?  179  CYS A SG  1 
ATOM   516  N N   . HIS A 1 180 ? 143.000 157.832 116.951 1.00 321.14 ?  180  HIS A N   1 
ATOM   517  C CA  . HIS A 1 180 ? 143.160 158.749 115.829 1.00 321.14 ?  180  HIS A CA  1 
ATOM   518  C C   . HIS A 1 180 ? 144.572 158.767 115.263 1.00 321.14 ?  180  HIS A C   1 
ATOM   519  O O   . HIS A 1 180 ? 144.752 158.772 114.047 1.00 321.14 ?  180  HIS A O   1 
ATOM   520  C CB  . HIS A 1 180 ? 142.770 160.160 116.254 1.00 321.14 ?  180  HIS A CB  1 
ATOM   521  C CG  . HIS A 1 180 ? 142.362 161.041 115.117 1.00 321.14 ?  180  HIS A CG  1 
ATOM   522  N ND1 . HIS A 1 180 ? 141.524 160.613 114.110 1.00 321.14 ?  180  HIS A ND1 1 
ATOM   523  C CD2 . HIS A 1 180 ? 142.678 162.324 114.825 1.00 321.14 ?  180  HIS A CD2 1 
ATOM   524  C CE1 . HIS A 1 180 ? 141.339 161.596 113.247 1.00 321.14 ?  180  HIS A CE1 1 
ATOM   525  N NE2 . HIS A 1 180 ? 142.029 162.645 113.657 1.00 321.14 ?  180  HIS A NE2 1 
ATOM   526  N N   . LEU A 1 181 ? 145.573 158.774 116.133 1.00 330.88 ?  181  LEU A N   1 
ATOM   527  C CA  . LEU A 1 181 ? 146.958 158.818 115.689 1.00 330.88 ?  181  LEU A CA  1 
ATOM   528  C C   . LEU A 1 181 ? 147.381 157.511 115.046 1.00 330.88 ?  181  LEU A C   1 
ATOM   529  O O   . LEU A 1 181 ? 147.785 157.493 113.888 1.00 330.88 ?  181  LEU A O   1 
ATOM   530  C CB  . LEU A 1 181 ? 147.876 159.112 116.874 1.00 330.88 ?  181  LEU A CB  1 
ATOM   531  C CG  . LEU A 1 181 ? 148.278 160.549 117.216 1.00 330.88 ?  181  LEU A CG  1 
ATOM   532  C CD1 . LEU A 1 181 ? 147.340 161.595 116.632 1.00 330.88 ?  181  LEU A CD1 1 
ATOM   533  C CD2 . LEU A 1 181 ? 148.396 160.706 118.723 1.00 330.88 ?  181  LEU A CD2 1 
ATOM   534  N N   . ILE A 1 182 ? 147.299 156.418 115.794 1.00 337.23 ?  182  ILE A N   1 
ATOM   535  C CA  . ILE A 1 182 ? 147.721 155.120 115.276 1.00 337.23 ?  182  ILE A CA  1 
ATOM   536  C C   . ILE A 1 182 ? 146.743 154.567 114.247 1.00 337.23 ?  182  ILE A C   1 
ATOM   537  O O   . ILE A 1 182 ? 147.027 154.572 113.051 1.00 337.23 ?  182  ILE A O   1 
ATOM   538  C CB  . ILE A 1 182 ? 147.927 154.102 116.413 1.00 337.23 ?  182  ILE A CB  1 
ATOM   539  C CG1 . ILE A 1 182 ? 148.737 154.733 117.540 1.00 337.23 ?  182  ILE A CG1 1 
ATOM   540  C CG2 . ILE A 1 182 ? 148.649 152.864 115.908 1.00 337.23 ?  182  ILE A CG2 1 
ATOM   541  C CD1 . ILE A 1 182 ? 150.224 154.488 117.428 1.00 337.23 ?  182  ILE A CD1 1 
ATOM   542  N N   . SER A 1 183 ? 145.593 154.091 114.701 1.00 277.75 ?  183  SER A N   1 
ATOM   543  C CA  . SER A 1 183 ? 144.626 153.512 113.783 1.00 277.75 ?  183  SER A CA  1 
ATOM   544  C C   . SER A 1 183 ? 143.224 154.025 114.043 1.00 277.75 ?  183  SER A C   1 
ATOM   545  O O   . SER A 1 183 ? 142.602 153.672 115.042 1.00 277.75 ?  183  SER A O   1 
ATOM   546  C CB  . SER A 1 183 ? 144.659 151.998 113.873 1.00 277.75 ?  183  SER A CB  1 
ATOM   547  O OG  . SER A 1 183 ? 143.395 151.443 113.582 1.00 277.75 ?  183  SER A OG  1 
ATOM   548  N N   . PRO A 1 184 ? 142.694 154.939 113.159 1.00 290.93 ?  184  PRO A N   1 
ATOM   549  C CA  . PRO A 1 184 ? 141.330 155.368 113.507 1.00 290.93 ?  184  PRO A CA  1 
ATOM   550  C C   . PRO A 1 184 ? 140.273 154.359 113.097 1.00 290.93 ?  184  PRO A C   1 
ATOM   551  O O   . PRO A 1 184 ? 139.091 154.686 113.090 1.00 290.93 ?  184  PRO A O   1 
ATOM   552  C CB  . PRO A 1 184 ? 141.158 156.651 112.702 1.00 290.93 ?  184  PRO A CB  1 
ATOM   553  C CG  . PRO A 1 184 ? 141.957 156.411 111.482 1.00 290.93 ?  184  PRO A CG  1 
ATOM   554  C CD  . PRO A 1 184 ? 143.187 155.729 111.995 1.00 290.93 ?  184  PRO A CD  1 
ATOM   555  N N   . GLN A 1 185 ? 140.689 153.147 112.760 1.00 300.55 ?  185  GLN A N   1 
ATOM   556  C CA  . GLN A 1 185 ? 139.742 152.103 112.401 1.00 300.55 ?  185  GLN A CA  1 
ATOM   557  C C   . GLN A 1 185 ? 139.723 151.139 113.552 1.00 300.55 ?  185  GLN A C   1 
ATOM   558  O O   . GLN A 1 185 ? 139.253 150.013 113.427 1.00 300.55 ?  185  GLN A O   1 
ATOM   559  C CB  . GLN A 1 185 ? 140.134 151.409 111.095 1.00 300.55 ?  185  GLN A CB  1 
ATOM   560  C CG  . GLN A 1 185 ? 141.624 151.232 110.874 1.00 300.55 ?  185  GLN A CG  1 
ATOM   561  C CD  . GLN A 1 185 ? 142.236 152.349 110.051 1.00 300.55 ?  185  GLN A CD  1 
ATOM   562  O OE1 . GLN A 1 185 ? 141.544 153.036 109.303 1.00 300.55 ?  185  GLN A OE1 1 
ATOM   563  N NE2 . GLN A 1 185 ? 143.542 152.537 110.191 1.00 300.55 ?  185  GLN A NE2 1 
ATOM   564  N N   . ALA A 1 186 ? 140.244 151.580 114.689 1.00 285.83 ?  186  ALA A N   1 
ATOM   565  C CA  . ALA A 1 186 ? 140.224 150.754 115.876 1.00 285.83 ?  186  ALA A CA  1 
ATOM   566  C C   . ALA A 1 186 ? 139.254 151.373 116.848 1.00 285.83 ?  186  ALA A C   1 
ATOM   567  O O   . ALA A 1 186 ? 139.394 151.218 118.047 1.00 285.83 ?  186  ALA A O   1 
ATOM   568  C CB  . ALA A 1 186 ? 141.600 150.686 116.491 1.00 285.83 ?  186  ALA A CB  1 
ATOM   569  N N   . VAL A 1 187 ? 138.275 152.102 116.331 1.00 285.09 ?  187  VAL A N   1 
ATOM   570  C CA  . VAL A 1 187 ? 137.278 152.717 117.187 1.00 285.09 ?  187  VAL A CA  1 
ATOM   571  C C   . VAL A 1 187 ? 136.005 151.886 117.195 1.00 285.09 ?  187  VAL A C   1 
ATOM   572  O O   . VAL A 1 187 ? 135.808 151.027 116.335 1.00 285.09 ?  187  VAL A O   1 
ATOM   573  C CB  . VAL A 1 187 ? 136.980 154.171 116.766 1.00 285.09 ?  187  VAL A CB  1 
ATOM   574  C CG1 . VAL A 1 187 ? 138.249 155.002 116.804 1.00 285.09 ?  187  VAL A CG1 1 
ATOM   575  C CG2 . VAL A 1 187 ? 136.362 154.218 115.379 1.00 285.09 ?  187  VAL A CG2 1 
ATOM   576  N N   . GLY A 1 188 ? 135.150 152.113 118.180 1.00 258.62 ?  188  GLY A N   1 
ATOM   577  C CA  . GLY A 1 188 ? 133.907 151.376 118.270 1.00 258.62 ?  188  GLY A CA  1 
ATOM   578  C C   . GLY A 1 188 ? 134.092 149.946 118.712 1.00 258.62 ?  188  GLY A C   1 
ATOM   579  O O   . GLY A 1 188 ? 135.114 149.593 119.290 1.00 258.62 ?  188  GLY A O   1 
ATOM   580  N N   . SER A 1 189 ? 133.110 149.094 118.433 1.00 249.74 ?  189  SER A N   1 
ATOM   581  C CA  . SER A 1 189 ? 133.236 147.675 118.757 1.00 249.74 ?  189  SER A CA  1 
ATOM   582  C C   . SER A 1 189 ? 133.941 146.982 117.618 1.00 249.74 ?  189  SER A C   1 
ATOM   583  O O   . SER A 1 189 ? 134.400 147.620 116.676 1.00 249.74 ?  189  SER A O   1 
ATOM   584  C CB  . SER A 1 189 ? 131.861 147.054 118.957 1.00 249.74 ?  189  SER A CB  1 
ATOM   585  O OG  . SER A 1 189 ? 131.788 146.351 120.179 1.00 249.74 ?  189  SER A OG  1 
ATOM   586  N N   . GLY A 1 190 ? 134.027 145.669 117.687 1.00 248.75 ?  190  GLY A N   1 
ATOM   587  C CA  . GLY A 1 190 ? 134.624 144.942 116.591 1.00 248.75 ?  190  GLY A CA  1 
ATOM   588  C C   . GLY A 1 190 ? 133.576 144.110 115.909 1.00 248.75 ?  190  GLY A C   1 
ATOM   589  O O   . GLY A 1 190 ? 133.579 144.021 114.694 1.00 248.75 ?  190  GLY A O   1 
ATOM   590  N N   . ILE A 1 191 ? 132.670 143.521 116.686 1.00 237.15 ?  191  ILE A N   1 
ATOM   591  C CA  . ILE A 1 191 ? 131.606 142.688 116.126 1.00 237.15 ?  191  ILE A CA  1 
ATOM   592  C C   . ILE A 1 191 ? 130.912 143.218 114.867 1.00 237.15 ?  191  ILE A C   1 
ATOM   593  O O   . ILE A 1 191 ? 130.886 142.512 113.878 1.00 237.15 ?  191  ILE A O   1 
ATOM   594  C CB  . ILE A 1 191 ? 130.548 142.263 117.172 1.00 237.15 ?  191  ILE A CB  1 
ATOM   595  C CG1 . ILE A 1 191 ? 131.133 142.291 118.579 1.00 237.15 ?  191  ILE A CG1 1 
ATOM   596  C CG2 . ILE A 1 191 ? 129.989 140.892 116.839 1.00 237.15 ?  191  ILE A CG2 1 
ATOM   597  C CD1 . ILE A 1 191 ? 130.532 141.264 119.513 1.00 237.15 ?  191  ILE A CD1 1 
ATOM   598  N N   . PRO A 1 192 ? 130.361 144.453 114.879 1.00 265.78 ?  192  PRO A N   1 
ATOM   599  C CA  . PRO A 1 192 ? 129.693 144.865 113.634 1.00 265.78 ?  192  PRO A CA  1 
ATOM   600  C C   . PRO A 1 192 ? 130.568 144.751 112.395 1.00 265.78 ?  192  PRO A C   1 
ATOM   601  O O   . PRO A 1 192 ? 130.111 144.295 111.349 1.00 265.78 ?  192  PRO A O   1 
ATOM   602  C CB  . PRO A 1 192 ? 129.378 146.337 113.878 1.00 265.78 ?  192  PRO A CB  1 
ATOM   603  C CG  . PRO A 1 192 ? 129.301 146.476 115.347 1.00 265.78 ?  192  PRO A CG  1 
ATOM   604  C CD  . PRO A 1 192 ? 130.285 145.511 115.907 1.00 265.78 ?  192  PRO A CD  1 
ATOM   605  N N   . GLU A 1 193 ? 131.823 145.155 112.506 1.00 275.33 ?  193  GLU A N   1 
ATOM   606  C CA  . GLU A 1 193 ? 132.723 145.121 111.367 1.00 275.33 ?  193  GLU A CA  1 
ATOM   607  C C   . GLU A 1 193 ? 133.263 143.730 111.109 1.00 275.33 ?  193  GLU A C   1 
ATOM   608  O O   . GLU A 1 193 ? 133.573 143.399 109.980 1.00 275.33 ?  193  GLU A O   1 
ATOM   609  C CB  . GLU A 1 193 ? 133.850 146.118 111.593 1.00 275.33 ?  193  GLU A CB  1 
ATOM   610  C CG  . GLU A 1 193 ? 133.344 147.540 111.791 1.00 275.33 ?  193  GLU A CG  1 
ATOM   611  C CD  . GLU A 1 193 ? 133.398 148.007 113.236 1.00 275.33 ?  193  GLU A CD  1 
ATOM   612  O OE1 . GLU A 1 193 ? 134.028 149.050 113.503 1.00 275.33 ?  193  GLU A OE1 1 
ATOM   613  O OE2 . GLU A 1 193 ? 132.801 147.345 114.106 1.00 275.33 -1 193  GLU A OE2 1 
ATOM   614  N N   . MET A 1 194 ? 133.354 142.901 112.142 1.00 255.21 ?  194  MET A N   1 
ATOM   615  C CA  . MET A 1 194 ? 133.784 141.520 111.954 1.00 255.21 ?  194  MET A CA  1 
ATOM   616  C C   . MET A 1 194 ? 132.684 140.748 111.275 1.00 255.21 ?  194  MET A C   1 
ATOM   617  O O   . MET A 1 194 ? 132.955 139.785 110.581 1.00 255.21 ?  194  MET A O   1 
ATOM   618  C CB  . MET A 1 194 ? 134.144 140.869 113.285 1.00 255.21 ?  194  MET A CB  1 
ATOM   619  C CG  . MET A 1 194 ? 135.536 141.226 113.779 1.00 255.21 ?  194  MET A CG  1 
ATOM   620  S SD  . MET A 1 194 ? 136.757 141.231 112.452 1.00 255.21 ?  194  MET A SD  1 
ATOM   621  C CE  . MET A 1 194 ? 137.139 142.977 112.321 1.00 255.21 ?  194  MET A CE  1 
ATOM   622  N N   . LYS A 1 195 ? 131.439 141.166 111.467 1.00 246.75 ?  195  LYS A N   1 
ATOM   623  C CA  . LYS A 1 195 ? 130.331 140.532 110.786 1.00 246.75 ?  195  LYS A CA  1 
ATOM   624  C C   . LYS A 1 195 ? 130.446 140.864 109.315 1.00 246.75 ?  195  LYS A C   1 
ATOM   625  O O   . LYS A 1 195 ? 130.229 140.008 108.468 1.00 246.75 ?  195  LYS A O   1 
ATOM   626  C CB  . LYS A 1 195 ? 129.018 141.086 111.302 1.00 246.75 ?  195  LYS A CB  1 
ATOM   627  C CG  . LYS A 1 195 ? 128.514 140.472 112.585 1.00 246.75 ?  195  LYS A CG  1 
ATOM   628  C CD  . LYS A 1 195 ? 127.685 141.480 113.361 1.00 246.75 ?  195  LYS A CD  1 
ATOM   629  C CE  . LYS A 1 195 ? 126.198 141.294 113.121 1.00 246.75 ?  195  LYS A CE  1 
ATOM   630  N NZ  . LYS A 1 195 ? 125.860 139.901 112.723 1.00 246.75 1  195  LYS A NZ  1 
ATOM   631  N N   . THR A 1 196 ? 130.767 142.114 109.008 1.00 271.27 ?  196  THR A N   1 
ATOM   632  C CA  . THR A 1 196 ? 130.941 142.522 107.622 1.00 271.27 ?  196  THR A CA  1 
ATOM   633  C C   . THR A 1 196 ? 132.059 141.716 106.976 1.00 271.27 ?  196  THR A C   1 
ATOM   634  O O   . THR A 1 196 ? 131.875 141.154 105.898 1.00 271.27 ?  196  THR A O   1 
ATOM   635  C CB  . THR A 1 196 ? 131.256 144.021 107.541 1.00 271.27 ?  196  THR A CB  1 
ATOM   636  O OG1 . THR A 1 196 ? 130.300 144.743 108.325 1.00 271.27 ?  196  THR A OG1 1 
ATOM   637  C CG2 . THR A 1 196 ? 131.206 144.513 106.116 1.00 271.27 ?  196  THR A CG2 1 
ATOM   638  N N   . ILE A 1 197 ? 133.216 141.655 107.627 1.00 285.13 ?  197  ILE A N   1 
ATOM   639  C CA  . ILE A 1 197 ? 134.326 140.868 107.107 1.00 285.13 ?  197  ILE A CA  1 
ATOM   640  C C   . ILE A 1 197 ? 133.899 139.422 106.888 1.00 285.13 ?  197  ILE A C   1 
ATOM   641  O O   . ILE A 1 197 ? 134.209 138.827 105.857 1.00 285.13 ?  197  ILE A O   1 
ATOM   642  C CB  . ILE A 1 197 ? 135.527 140.938 108.071 1.00 285.13 ?  197  ILE A CB  1 
ATOM   643  C CG1 . ILE A 1 197 ? 136.054 142.364 108.136 1.00 285.13 ?  197  ILE A CG1 1 
ATOM   644  C CG2 . ILE A 1 197 ? 136.646 139.999 107.654 1.00 285.13 ?  197  ILE A CG2 1 
ATOM   645  C CD1 . ILE A 1 197 ? 137.530 142.447 108.421 1.00 285.13 ?  197  ILE A CD1 1 
ATOM   646  N N   . LEU A 1 198 ? 133.145 138.865 107.829 1.00 250.77 ?  198  LEU A N   1 
ATOM   647  C CA  . LEU A 1 198 ? 132.731 137.466 107.729 1.00 250.77 ?  198  LEU A CA  1 
ATOM   648  C C   . LEU A 1 198 ? 131.633 137.240 106.702 1.00 250.77 ?  198  LEU A C   1 
ATOM   649  O O   . LEU A 1 198 ? 131.290 136.099 106.408 1.00 250.77 ?  198  LEU A O   1 
ATOM   650  C CB  . LEU A 1 198 ? 132.315 136.915 109.097 1.00 250.77 ?  198  LEU A CB  1 
ATOM   651  C CG  . LEU A 1 198 ? 133.363 136.031 109.778 1.00 250.77 ?  198  LEU A CG  1 
ATOM   652  C CD1 . LEU A 1 198 ? 134.728 136.258 109.161 1.00 250.77 ?  198  LEU A CD1 1 
ATOM   653  C CD2 . LEU A 1 198 ? 133.428 136.285 111.271 1.00 250.77 ?  198  LEU A CD2 1 
ATOM   654  N N   . ARG A 1 199 ? 131.081 138.312 106.143 1.00 291.37 ?  199  ARG A N   1 
ATOM   655  C CA  . ARG A 1 199 ? 130.087 138.170 105.088 1.00 291.37 ?  199  ARG A CA  1 
ATOM   656  C C   . ARG A 1 199 ? 130.766 138.354 103.743 1.00 291.37 ?  199  ARG A C   1 
ATOM   657  O O   . ARG A 1 199 ? 130.114 138.656 102.747 1.00 291.37 ?  199  ARG A O   1 
ATOM   658  C CB  . ARG A 1 199 ? 128.948 139.171 105.272 1.00 291.37 ?  199  ARG A CB  1 
ATOM   659  C CG  . ARG A 1 199 ? 127.568 138.556 105.111 1.00 291.37 ?  199  ARG A CG  1 
ATOM   660  C CD  . ARG A 1 199 ? 126.800 138.527 106.418 1.00 291.37 ?  199  ARG A CD  1 
ATOM   661  N NE  . ARG A 1 199 ? 127.693 138.430 107.566 1.00 291.37 ?  199  ARG A NE  1 
ATOM   662  C CZ  . ARG A 1 199 ? 127.343 137.941 108.749 1.00 291.37 ?  199  ARG A CZ  1 
ATOM   663  N NH1 . ARG A 1 199 ? 126.108 137.503 108.955 1.00 291.37 1  199  ARG A NH1 1 
ATOM   664  N NH2 . ARG A 1 199 ? 128.227 137.898 109.728 1.00 291.37 ?  199  ARG A NH2 1 
ATOM   665  N N   . GLY A 1 200 ? 132.083 138.188 103.710 1.00 276.46 ?  200  GLY A N   1 
ATOM   666  C CA  . GLY A 1 200 ? 132.816 138.290 102.463 1.00 276.46 ?  200  GLY A CA  1 
ATOM   667  C C   . GLY A 1 200 ? 133.460 139.631 102.207 1.00 276.46 ?  200  GLY A C   1 
ATOM   668  O O   . GLY A 1 200 ? 134.508 139.701 101.574 1.00 276.46 ?  200  GLY A O   1 
ATOM   669  N N   . VAL A 1 201 ? 132.843 140.702 102.685 1.00 264.22 ?  201  VAL A N   1 
ATOM   670  C CA  . VAL A 1 201 ? 133.366 142.030 102.407 1.00 264.22 ?  201  VAL A CA  1 
ATOM   671  C C   . VAL A 1 201 ? 134.437 142.413 103.400 1.00 264.22 ?  201  VAL A C   1 
ATOM   672  O O   . VAL A 1 201 ? 134.181 143.155 104.346 1.00 264.22 ?  201  VAL A O   1 
ATOM   673  C CB  . VAL A 1 201 ? 132.244 143.070 102.370 1.00 264.22 ?  201  VAL A CB  1 
ATOM   674  C CG1 . VAL A 1 201 ? 132.175 143.673 100.977 1.00 264.22 ?  201  VAL A CG1 1 
ATOM   675  C CG2 . VAL A 1 201 ? 130.915 142.415 102.719 1.00 264.22 ?  201  VAL A CG2 1 
ATOM   676  N N   . VAL A 1 202 ? 135.650 141.931 103.171 1.00 240.15 ?  202  VAL A N   1 
ATOM   677  C CA  . VAL A 1 202 ? 136.731 142.171 104.116 1.00 240.15 ?  202  VAL A CA  1 
ATOM   678  C C   . VAL A 1 202 ? 137.367 143.553 104.040 1.00 240.15 ?  202  VAL A C   1 
ATOM   679  O O   . VAL A 1 202 ? 137.827 143.982 102.980 1.00 240.15 ?  202  VAL A O   1 
ATOM   680  C CB  . VAL A 1 202 ? 137.792 141.042 104.014 1.00 240.15 ?  202  VAL A CB  1 
ATOM   681  C CG1 . VAL A 1 202 ? 138.069 140.668 102.566 1.00 240.15 ?  202  VAL A CG1 1 
ATOM   682  C CG2 . VAL A 1 202 ? 139.070 141.377 104.770 1.00 240.15 ?  202  VAL A CG2 1 
ATOM   683  N N   . LEU A 1 203 ? 137.354 144.277 105.153 1.00 252.28 ?  203  LEU A N   1 
ATOM   684  C CA  . LEU A 1 203 ? 138.020 145.566 105.198 1.00 252.28 ?  203  LEU A CA  1 
ATOM   685  C C   . LEU A 1 203 ? 139.392 145.213 105.717 1.00 252.28 ?  203  LEU A C   1 
ATOM   686  O O   . LEU A 1 203 ? 139.515 144.659 106.803 1.00 252.28 ?  203  LEU A O   1 
ATOM   687  C CB  . LEU A 1 203 ? 137.297 146.499 106.160 1.00 252.28 ?  203  LEU A CB  1 
ATOM   688  C CG  . LEU A 1 203 ? 135.937 146.011 106.670 1.00 252.28 ?  203  LEU A CG  1 
ATOM   689  C CD1 . LEU A 1 203 ? 135.782 146.304 108.152 1.00 252.28 ?  203  LEU A CD1 1 
ATOM   690  C CD2 . LEU A 1 203 ? 134.787 146.618 105.880 1.00 252.28 ?  203  LEU A CD2 1 
ATOM   691  N N   . LYS A 1 204 ? 140.438 145.506 104.959 1.00 266.35 ?  204  LYS A N   1 
ATOM   692  C CA  . LYS A 1 204 ? 141.770 145.064 105.375 1.00 266.35 ?  204  LYS A CA  1 
ATOM   693  C C   . LYS A 1 204 ? 142.575 146.015 106.250 1.00 266.35 ?  204  LYS A C   1 
ATOM   694  O O   . LYS A 1 204 ? 143.754 145.773 106.497 1.00 266.35 ?  204  LYS A O   1 
ATOM   695  C CB  . LYS A 1 204 ? 142.595 144.615 104.165 1.00 266.35 ?  204  LYS A CB  1 
ATOM   696  C CG  . LYS A 1 204 ? 142.896 143.122 104.141 1.00 266.35 ?  204  LYS A CG  1 
ATOM   697  C CD  . LYS A 1 204 ? 142.708 142.473 105.507 1.00 266.35 ?  204  LYS A CD  1 
ATOM   698  C CE  . LYS A 1 204 ? 144.022 141.959 106.074 1.00 266.35 ?  204  LYS A CE  1 
ATOM   699  N NZ  . LYS A 1 204 ? 144.638 142.930 107.019 1.00 266.35 1  204  LYS A NZ  1 
ATOM   700  N N   . GLU A 1 205 ? 141.966 147.092 106.724 1.00 287.44 ?  205  GLU A N   1 
ATOM   701  C CA  . GLU A 1 205 ? 142.679 147.957 107.654 1.00 287.44 ?  205  GLU A CA  1 
ATOM   702  C C   . GLU A 1 205 ? 142.195 147.574 109.027 1.00 287.44 ?  205  GLU A C   1 
ATOM   703  O O   . GLU A 1 205 ? 142.767 147.970 110.038 1.00 287.44 ?  205  GLU A O   1 
ATOM   704  C CB  . GLU A 1 205 ? 142.425 149.427 107.360 1.00 287.44 ?  205  GLU A CB  1 
ATOM   705  C CG  . GLU A 1 205 ? 143.705 150.236 107.269 1.00 287.44 ?  205  GLU A CG  1 
ATOM   706  C CD  . GLU A 1 205 ? 143.630 151.322 106.220 1.00 287.44 ?  205  GLU A CD  1 
ATOM   707  O OE1 . GLU A 1 205 ? 144.016 152.469 106.525 1.00 287.44 ?  205  GLU A OE1 1 
ATOM   708  O OE2 . GLU A 1 205 ? 143.186 151.026 105.092 1.00 287.44 -1 205  GLU A OE2 1 
ATOM   709  N N   . TYR A 1 206 ? 141.163 146.758 109.075 1.00 270.14 ?  206  TYR A N   1 
ATOM   710  C CA  . TYR A 1 206 ? 140.677 146.330 110.360 1.00 270.14 ?  206  TYR A CA  1 
ATOM   711  C C   . TYR A 1 206 ? 141.610 145.311 110.971 1.00 270.14 ?  206  TYR A C   1 
ATOM   712  O O   . TYR A 1 206 ? 141.920 145.373 112.155 1.00 270.14 ?  206  TYR A O   1 
ATOM   713  C CB  . TYR A 1 206 ? 139.249 145.854 110.283 1.00 270.14 ?  206  TYR A CB  1 
ATOM   714  C CG  . TYR A 1 206 ? 138.355 147.010 110.575 1.00 270.14 ?  206  TYR A CG  1 
ATOM   715  C CD1 . TYR A 1 206 ? 138.267 148.078 109.690 1.00 270.14 ?  206  TYR A CD1 1 
ATOM   716  C CD2 . TYR A 1 206 ? 137.662 147.084 111.760 1.00 270.14 ?  206  TYR A CD2 1 
ATOM   717  C CE1 . TYR A 1 206 ? 137.459 149.157 109.951 1.00 270.14 ?  206  TYR A CE1 1 
ATOM   718  C CE2 . TYR A 1 206 ? 136.868 148.165 112.036 1.00 270.14 ?  206  TYR A CE2 1 
ATOM   719  C CZ  . TYR A 1 206 ? 136.765 149.198 111.127 1.00 270.14 ?  206  TYR A CZ  1 
ATOM   720  O OH  . TYR A 1 206 ? 135.969 150.285 111.397 1.00 270.14 ?  206  TYR A OH  1 
ATOM   721  N N   . LEU A 1 207 ? 142.089 144.387 110.155 1.00 249.20 ?  207  LEU A N   1 
ATOM   722  C CA  . LEU A 1 207 ? 142.967 143.360 110.702 1.00 249.20 ?  207  LEU A CA  1 
ATOM   723  C C   . LEU A 1 207 ? 144.438 143.707 110.581 1.00 249.20 ?  207  LEU A C   1 
ATOM   724  O O   . LEU A 1 207 ? 145.227 142.889 110.120 1.00 249.20 ?  207  LEU A O   1 
ATOM   725  C CB  . LEU A 1 207 ? 142.705 142.019 110.018 1.00 249.20 ?  207  LEU A CB  1 
ATOM   726  C CG  . LEU A 1 207 ? 141.709 141.054 110.658 1.00 249.20 ?  207  LEU A CG  1 
ATOM   727  C CD1 . LEU A 1 207 ? 141.065 141.649 111.896 1.00 249.20 ?  207  LEU A CD1 1 
ATOM   728  C CD2 . LEU A 1 207 ? 140.650 140.663 109.646 1.00 249.20 ?  207  LEU A CD2 1 
ATOM   729  N N   . THR A 1 208 ? 144.820 144.910 110.995 1.00 277.04 ?  208  THR A N   1 
ATOM   730  C CA  . THR A 1 208 ? 146.225 145.290 110.971 1.00 277.04 ?  208  THR A CA  1 
ATOM   731  C C   . THR A 1 208 ? 146.802 145.315 112.373 1.00 277.04 ?  208  THR A C   1 
ATOM   732  O O   . THR A 1 208 ? 146.063 145.300 113.348 1.00 277.04 ?  208  THR A O   1 
ATOM   733  C CB  . THR A 1 208 ? 146.436 146.672 110.339 1.00 277.04 ?  208  THR A CB  1 
ATOM   734  O OG1 . THR A 1 208 ? 145.516 147.608 110.911 1.00 277.04 ?  208  THR A OG1 1 
ATOM   735  C CG2 . THR A 1 208 ? 146.230 146.611 108.842 1.00 277.04 ?  208  THR A CG2 1 
ATOM   736  N N   . MET A 1 209 ? 148.123 145.376 112.478 1.00 249.61 ?  209  MET A N   1 
ATOM   737  C CA  . MET A 1 209 ? 148.769 145.423 113.782 1.00 249.61 ?  209  MET A CA  1 
ATOM   738  C C   . MET A 1 209 ? 148.675 146.807 114.383 1.00 249.61 ?  209  MET A C   1 
ATOM   739  O O   . MET A 1 209 ? 148.769 146.965 115.593 1.00 249.61 ?  209  MET A O   1 
ATOM   740  C CB  . MET A 1 209 ? 150.231 145.003 113.677 1.00 249.61 ?  209  MET A CB  1 
ATOM   741  C CG  . MET A 1 209 ? 150.492 143.561 114.078 1.00 249.61 ?  209  MET A CG  1 
ATOM   742  S SD  . MET A 1 209 ? 149.898 143.167 115.734 1.00 249.61 ?  209  MET A SD  1 
ATOM   743  C CE  . MET A 1 209 ? 151.056 144.085 116.744 1.00 249.61 ?  209  MET A CE  1 
ATOM   744  N N   . LYS A 1 210 ? 148.497 147.819 113.548 1.00 257.56 ?  210  LYS A N   1 
ATOM   745  C CA  . LYS A 1 210 ? 148.312 149.164 114.064 1.00 257.56 ?  210  LYS A CA  1 
ATOM   746  C C   . LYS A 1 210 ? 146.984 149.172 114.780 1.00 257.56 ?  210  LYS A C   1 
ATOM   747  O O   . LYS A 1 210 ? 146.875 149.711 115.876 1.00 257.56 ?  210  LYS A O   1 
ATOM   748  C CB  . LYS A 1 210 ? 148.311 150.183 112.931 1.00 257.56 ?  210  LYS A CB  1 
ATOM   749  C CG  . LYS A 1 210 ? 148.726 149.612 111.586 1.00 257.56 ?  210  LYS A CG  1 
ATOM   750  C CD  . LYS A 1 210 ? 150.170 149.954 111.255 1.00 257.56 ?  210  LYS A CD  1 
ATOM   751  C CE  . LYS A 1 210 ? 150.999 148.699 111.021 1.00 257.56 ?  210  LYS A CE  1 
ATOM   752  N NZ  . LYS A 1 210 ? 150.155 147.536 110.629 1.00 257.56 1  210  LYS A NZ  1 
ATOM   753  N N   . ALA A 1 211 ? 145.975 148.553 114.176 1.00 269.25 ?  211  ALA A N   1 
ATOM   754  C CA  . ALA A 1 211 ? 144.677 148.457 114.820 1.00 269.25 ?  211  ALA A CA  1 
ATOM   755  C C   . ALA A 1 211 ? 144.789 147.730 116.137 1.00 269.25 ?  211  ALA A C   1 
ATOM   756  O O   . ALA A 1 211 ? 144.175 148.139 117.107 1.00 269.25 ?  211  ALA A O   1 
ATOM   757  C CB  . ALA A 1 211 ? 143.680 147.765 113.916 1.00 269.25 ?  211  ALA A CB  1 
ATOM   758  N N   . PHE A 1 212 ? 145.574 146.658 116.180 1.00 256.48 ?  212  PHE A N   1 
ATOM   759  C CA  . PHE A 1 212 ? 145.772 145.916 117.413 1.00 256.48 ?  212  PHE A CA  1 
ATOM   760  C C   . PHE A 1 212 ? 146.261 146.834 118.497 1.00 256.48 ?  212  PHE A C   1 
ATOM   761  O O   . PHE A 1 212 ? 145.593 147.002 119.500 1.00 256.48 ?  212  PHE A O   1 
ATOM   762  C CB  . PHE A 1 212 ? 146.786 144.804 117.207 1.00 256.48 ?  212  PHE A CB  1 
ATOM   763  C CG  . PHE A 1 212 ? 146.822 143.799 118.317 1.00 256.48 ?  212  PHE A CG  1 
ATOM   764  C CD1 . PHE A 1 212 ? 145.781 142.909 118.494 1.00 256.48 ?  212  PHE A CD1 1 
ATOM   765  C CD2 . PHE A 1 212 ? 147.901 143.742 119.181 1.00 256.48 ?  212  PHE A CD2 1 
ATOM   766  C CE1 . PHE A 1 212 ? 145.815 141.979 119.509 1.00 256.48 ?  212  PHE A CE1 1 
ATOM   767  C CE2 . PHE A 1 212 ? 147.938 142.815 120.202 1.00 256.48 ?  212  PHE A CE2 1 
ATOM   768  C CZ  . PHE A 1 212 ? 146.892 141.933 120.367 1.00 256.48 ?  212  PHE A CZ  1 
ATOM   769  N N   . VAL A 1 213 ? 147.425 147.432 118.295 1.00 248.50 ?  213  VAL A N   1 
ATOM   770  C CA  . VAL A 1 213 ? 148.000 148.314 119.300 1.00 248.50 ?  213  VAL A CA  1 
ATOM   771  C C   . VAL A 1 213 ? 147.005 149.377 119.738 1.00 248.50 ?  213  VAL A C   1 
ATOM   772  O O   . VAL A 1 213 ? 146.751 149.527 120.925 1.00 248.50 ?  213  VAL A O   1 
ATOM   773  C CB  . VAL A 1 213 ? 149.305 148.960 118.798 1.00 248.50 ?  213  VAL A CB  1 
ATOM   774  C CG1 . VAL A 1 213 ? 149.875 149.921 119.827 1.00 248.50 ?  213  VAL A CG1 1 
ATOM   775  C CG2 . VAL A 1 213 ? 150.325 147.881 118.478 1.00 248.50 ?  213  VAL A CG2 1 
ATOM   776  N N   . ALA A 1 214 ? 146.418 150.091 118.783 1.00 277.83 ?  214  ALA A N   1 
ATOM   777  C CA  . ALA A 1 214 ? 145.465 151.135 119.118 1.00 277.83 ?  214  ALA A CA  1 
ATOM   778  C C   . ALA A 1 214 ? 144.363 150.590 119.999 1.00 277.83 ?  214  ALA A C   1 
ATOM   779  O O   . ALA A 1 214 ? 144.189 151.050 121.114 1.00 277.83 ?  214  ALA A O   1 
ATOM   780  C CB  . ALA A 1 214 ? 144.890 151.768 117.868 1.00 277.83 ?  214  ALA A CB  1 
ATOM   781  N N   . LYS A 1 215 ? 143.645 149.582 119.517 1.00 263.72 ?  215  LYS A N   1 
ATOM   782  C CA  . LYS A 1 215 ? 142.553 148.997 120.283 1.00 263.72 ?  215  LYS A CA  1 
ATOM   783  C C   . LYS A 1 215 ? 142.993 148.541 121.663 1.00 263.72 ?  215  LYS A C   1 
ATOM   784  O O   . LYS A 1 215 ? 142.342 148.861 122.641 1.00 263.72 ?  215  LYS A O   1 
ATOM   785  C CB  . LYS A 1 215 ? 141.915 147.839 119.521 1.00 263.72 ?  215  LYS A CB  1 
ATOM   786  C CG  . LYS A 1 215 ? 140.426 147.684 119.768 1.00 263.72 ?  215  LYS A CG  1 
ATOM   787  C CD  . LYS A 1 215 ? 139.640 147.927 118.497 1.00 263.72 ?  215  LYS A CD  1 
ATOM   788  C CE  . LYS A 1 215 ? 138.143 147.923 118.743 1.00 263.72 ?  215  LYS A CE  1 
ATOM   789  N NZ  . LYS A 1 215 ? 137.376 148.241 117.508 1.00 263.72 1  215  LYS A NZ  1 
ATOM   790  N N   . VAL A 1 216 ? 144.090 147.799 121.748 1.00 243.99 ?  216  VAL A N   1 
ATOM   791  C CA  . VAL A 1 216 ? 144.564 147.287 123.034 1.00 243.99 ?  216  VAL A CA  1 
ATOM   792  C C   . VAL A 1 216 ? 144.795 148.409 124.034 1.00 243.99 ?  216  VAL A C   1 
ATOM   793  O O   . VAL A 1 216 ? 144.132 148.460 125.065 1.00 243.99 ?  216  VAL A O   1 
ATOM   794  C CB  . VAL A 1 216 ? 145.842 146.420 122.893 1.00 243.99 ?  216  VAL A CB  1 
ATOM   795  C CG1 . VAL A 1 216 ? 146.477 146.138 124.246 1.00 243.99 ?  216  VAL A CG1 1 
ATOM   796  C CG2 . VAL A 1 216 ? 145.512 145.106 122.216 1.00 243.99 ?  216  VAL A CG2 1 
ATOM   797  N N   . VAL A 1 217 ? 145.694 149.332 123.722 1.00 240.87 ?  217  VAL A N   1 
ATOM   798  C CA  . VAL A 1 217 ? 146.029 150.391 124.663 1.00 240.87 ?  217  VAL A CA  1 
ATOM   799  C C   . VAL A 1 217 ? 144.840 151.276 124.982 1.00 240.87 ?  217  VAL A C   1 
ATOM   800  O O   . VAL A 1 217 ? 144.582 151.591 126.141 1.00 240.87 ?  217  VAL A O   1 
ATOM   801  C CB  . VAL A 1 217 ? 147.214 151.229 124.146 1.00 240.87 ?  217  VAL A CB  1 
ATOM   802  C CG1 . VAL A 1 217 ? 147.716 152.175 125.218 1.00 240.87 ?  217  VAL A CG1 1 
ATOM   803  C CG2 . VAL A 1 217 ? 148.349 150.312 123.726 1.00 240.87 ?  217  VAL A CG2 1 
ATOM   804  N N   . ALA A 1 218 ? 144.088 151.655 123.963 1.00 248.37 ?  218  ALA A N   1 
ATOM   805  C CA  . ALA A 1 218 ? 142.958 152.541 124.177 1.00 248.37 ?  218  ALA A CA  1 
ATOM   806  C C   . ALA A 1 218 ? 141.816 151.895 124.952 1.00 248.37 ?  218  ALA A C   1 
ATOM   807  O O   . ALA A 1 218 ? 141.130 152.566 125.711 1.00 248.37 ?  218  ALA A O   1 
ATOM   808  C CB  . ALA A 1 218 ? 142.479 153.085 122.855 1.00 248.37 ?  218  ALA A CB  1 
ATOM   809  N N   . LEU A 1 219 ? 141.612 150.597 124.781 1.00 254.00 ?  219  LEU A N   1 
ATOM   810  C CA  . LEU A 1 219 ? 140.591 149.909 125.548 1.00 254.00 ?  219  LEU A CA  1 
ATOM   811  C C   . LEU A 1 219 ? 141.011 149.819 126.996 1.00 254.00 ?  219  LEU A C   1 
ATOM   812  O O   . LEU A 1 219 ? 140.203 150.042 127.873 1.00 254.00 ?  219  LEU A O   1 
ATOM   813  C CB  . LEU A 1 219 ? 140.354 148.516 125.000 1.00 254.00 ?  219  LEU A CB  1 
ATOM   814  C CG  . LEU A 1 219 ? 139.152 147.721 125.478 1.00 254.00 ?  219  LEU A CG  1 
ATOM   815  C CD1 . LEU A 1 219 ? 137.863 148.481 125.235 1.00 254.00 ?  219  LEU A CD1 1 
ATOM   816  C CD2 . LEU A 1 219 ? 139.156 146.416 124.723 1.00 254.00 ?  219  LEU A CD2 1 
ATOM   817  N N   . THR A 1 220 ? 142.276 149.513 127.258 1.00 260.38 ?  220  THR A N   1 
ATOM   818  C CA  . THR A 1 220 ? 142.765 149.495 128.631 1.00 260.38 ?  220  THR A CA  1 
ATOM   819  C C   . THR A 1 220 ? 142.465 150.819 129.318 1.00 260.38 ?  220  THR A C   1 
ATOM   820  O O   . THR A 1 220 ? 141.971 150.844 130.444 1.00 260.38 ?  220  THR A O   1 
ATOM   821  C CB  . THR A 1 220 ? 144.279 149.243 128.690 1.00 260.38 ?  220  THR A CB  1 
ATOM   822  O OG1 . THR A 1 220 ? 144.643 148.270 127.712 1.00 260.38 ?  220  THR A OG1 1 
ATOM   823  C CG2 . THR A 1 220 ? 144.672 148.739 130.046 1.00 260.38 ?  220  THR A CG2 1 
ATOM   824  N N   . ALA A 1 221 ? 142.745 151.924 128.638 1.00 244.81 ?  221  ALA A N   1 
ATOM   825  C CA  . ALA A 1 221 ? 142.480 153.236 129.205 1.00 244.81 ?  221  ALA A CA  1 
ATOM   826  C C   . ALA A 1 221 ? 140.994 153.467 129.422 1.00 244.81 ?  221  ALA A C   1 
ATOM   827  O O   . ALA A 1 221 ? 140.596 154.003 130.448 1.00 244.81 ?  221  ALA A O   1 
ATOM   828  C CB  . ALA A 1 221 ? 143.069 154.312 128.317 1.00 244.81 ?  221  ALA A CB  1 
ATOM   829  N N   . GLY A 1 222 ? 140.168 153.056 128.471 1.00 244.62 ?  222  GLY A N   1 
ATOM   830  C CA  . GLY A 1 222 ? 138.732 153.197 128.617 1.00 244.62 ?  222  GLY A CA  1 
ATOM   831  C C   . GLY A 1 222 ? 138.130 152.363 129.730 1.00 244.62 ?  222  GLY A C   1 
ATOM   832  O O   . GLY A 1 222 ? 137.147 152.762 130.340 1.00 244.62 ?  222  GLY A O   1 
ATOM   833  N N   . LEU A 1 223 ? 138.711 151.202 130.007 1.00 242.33 ?  223  LEU A N   1 
ATOM   834  C CA  . LEU A 1 223 ? 138.200 150.339 131.062 1.00 242.33 ?  223  LEU A CA  1 
ATOM   835  C C   . LEU A 1 223 ? 138.721 150.744 132.419 1.00 242.33 ?  223  LEU A C   1 
ATOM   836  O O   . LEU A 1 223 ? 138.156 150.364 133.435 1.00 242.33 ?  223  LEU A O   1 
ATOM   837  C CB  . LEU A 1 223 ? 138.565 148.885 130.807 1.00 242.33 ?  223  LEU A CB  1 
ATOM   838  C CG  . LEU A 1 223 ? 138.081 148.207 129.537 1.00 242.33 ?  223  LEU A CG  1 
ATOM   839  C CD1 . LEU A 1 223 ? 139.001 147.029 129.267 1.00 242.33 ?  223  LEU A CD1 1 
ATOM   840  C CD2 . LEU A 1 223 ? 136.630 147.778 129.668 1.00 242.33 ?  223  LEU A CD2 1 
ATOM   841  N N   . GLY A 1 224 ? 139.801 151.510 132.445 1.00 257.32 ?  224  GLY A N   1 
ATOM   842  C CA  . GLY A 1 224 ? 140.349 151.976 133.699 1.00 257.32 ?  224  GLY A CA  1 
ATOM   843  C C   . GLY A 1 224 ? 139.844 153.355 134.026 1.00 257.32 ?  224  GLY A C   1 
ATOM   844  O O   . GLY A 1 224 ? 140.297 153.977 134.981 1.00 257.32 ?  224  GLY A O   1 
ATOM   845  N N   . SER A 1 225 ? 138.902 153.846 133.235 1.00 236.65 ?  225  SER A N   1 
ATOM   846  C CA  . SER A 1 225 ? 138.341 155.160 133.477 1.00 236.65 ?  225  SER A CA  1 
ATOM   847  C C   . SER A 1 225 ? 137.087 155.070 134.324 1.00 236.65 ?  225  SER A C   1 
ATOM   848  O O   . SER A 1 225 ? 136.807 155.966 135.114 1.00 236.65 ?  225  SER A O   1 
ATOM   849  C CB  . SER A 1 225 ? 138.037 155.854 132.156 1.00 236.65 ?  225  SER A CB  1 
ATOM   850  O OG  . SER A 1 225 ? 136.943 155.247 131.506 1.00 236.65 ?  225  SER A OG  1 
ATOM   851  N N   . GLY A 1 226 ? 136.324 153.996 134.168 1.00 225.32 ?  226  GLY A N   1 
ATOM   852  C CA  . GLY A 1 226 ? 135.077 153.863 134.898 1.00 225.32 ?  226  GLY A CA  1 
ATOM   853  C C   . GLY A 1 226 ? 133.898 154.359 134.094 1.00 225.32 ?  226  GLY A C   1 
ATOM   854  O O   . GLY A 1 226 ? 132.767 154.322 134.565 1.00 225.32 ?  226  GLY A O   1 
ATOM   855  N N   . ILE A 1 227 ? 134.155 154.826 132.879 1.00 196.92 ?  227  ILE A N   1 
ATOM   856  C CA  . ILE A 1 227 ? 133.094 155.308 132.009 1.00 196.92 ?  227  ILE A CA  1 
ATOM   857  C C   . ILE A 1 227 ? 132.486 154.059 131.415 1.00 196.92 ?  227  ILE A C   1 
ATOM   858  O O   . ILE A 1 227 ? 133.225 153.144 131.075 1.00 196.92 ?  227  ILE A O   1 
ATOM   859  C CB  . ILE A 1 227 ? 133.680 156.242 130.923 1.00 196.92 ?  227  ILE A CB  1 
ATOM   860  C CG1 . ILE A 1 227 ? 134.253 157.499 131.573 1.00 196.92 ?  227  ILE A CG1 1 
ATOM   861  C CG2 . ILE A 1 227 ? 132.655 156.640 129.874 1.00 196.92 ?  227  ILE A CG2 1 
ATOM   862  C CD1 . ILE A 1 227 ? 133.273 158.246 132.448 1.00 196.92 ?  227  ILE A CD1 1 
ATOM   863  N N   . PRO A 1 228 ? 131.107 153.984 131.293 1.00 174.25 ?  228  PRO A N   1 
ATOM   864  C CA  . PRO A 1 228 ? 130.586 152.709 130.769 1.00 174.25 ?  228  PRO A CA  1 
ATOM   865  C C   . PRO A 1 228 ? 130.887 152.372 129.323 1.00 174.25 ?  228  PRO A C   1 
ATOM   866  O O   . PRO A 1 228 ? 130.038 152.572 128.458 1.00 174.25 ?  228  PRO A O   1 
ATOM   867  C CB  . PRO A 1 228 ? 129.072 152.846 130.946 1.00 174.25 ?  228  PRO A CB  1 
ATOM   868  C CG  . PRO A 1 228 ? 128.809 154.302 130.981 1.00 174.25 ?  228  PRO A CG  1 
ATOM   869  C CD  . PRO A 1 228 ? 129.966 154.835 131.745 1.00 174.25 ?  228  PRO A CD  1 
ATOM   870  N N   . VAL A 1 229 ? 132.076 151.848 129.051 1.00 202.83 ?  229  VAL A N   1 
ATOM   871  C CA  . VAL A 1 229 ? 132.417 151.392 127.712 1.00 202.83 ?  229  VAL A CA  1 
ATOM   872  C C   . VAL A 1 229 ? 132.580 149.903 127.938 1.00 202.83 ?  229  VAL A C   1 
ATOM   873  O O   . VAL A 1 229 ? 132.654 149.456 129.085 1.00 202.83 ?  229  VAL A O   1 
ATOM   874  C CB  . VAL A 1 229 ? 133.700 152.052 127.173 1.00 202.83 ?  229  VAL A CB  1 
ATOM   875  C CG1 . VAL A 1 229 ? 133.617 153.562 127.319 1.00 202.83 ?  229  VAL A CG1 1 
ATOM   876  C CG2 . VAL A 1 229 ? 134.943 151.513 127.863 1.00 202.83 ?  229  VAL A CG2 1 
ATOM   877  N N   . GLY A 1 230 ? 132.623 149.106 126.884 1.00 199.38 ?  230  GLY A N   1 
ATOM   878  C CA  . GLY A 1 230 ? 132.683 147.672 127.090 1.00 199.38 ?  230  GLY A CA  1 
ATOM   879  C C   . GLY A 1 230 ? 133.938 147.001 126.607 1.00 199.38 ?  230  GLY A C   1 
ATOM   880  O O   . GLY A 1 230 ? 134.547 147.442 125.638 1.00 199.38 ?  230  GLY A O   1 
ATOM   881  N N   . LYS A 1 231 ? 134.341 145.935 127.282 1.00 223.11 ?  231  LYS A N   1 
ATOM   882  C CA  . LYS A 1 231 ? 135.492 145.180 126.829 1.00 223.11 ?  231  LYS A CA  1 
ATOM   883  C C   . LYS A 1 231 ? 134.985 144.186 125.814 1.00 223.11 ?  231  LYS A C   1 
ATOM   884  O O   . LYS A 1 231 ? 135.629 143.944 124.801 1.00 223.11 ?  231  LYS A O   1 
ATOM   885  C CB  . LYS A 1 231 ? 136.130 144.444 127.998 1.00 223.11 ?  231  LYS A CB  1 
ATOM   886  C CG  . LYS A 1 231 ? 135.196 144.212 129.171 1.00 223.11 ?  231  LYS A CG  1 
ATOM   887  C CD  . LYS A 1 231 ? 135.856 143.319 130.203 1.00 223.11 ?  231  LYS A CD  1 
ATOM   888  C CE  . LYS A 1 231 ? 137.362 143.284 130.010 1.00 223.11 ?  231  LYS A CE  1 
ATOM   889  N NZ  . LYS A 1 231 ? 137.919 141.913 130.168 1.00 223.11 1  231  LYS A NZ  1 
ATOM   890  N N   . GLU A 1 232 ? 133.818 143.611 126.079 1.00 245.05 ?  232  GLU A N   1 
ATOM   891  C CA  . GLU A 1 232 ? 133.229 142.632 125.173 1.00 245.05 ?  232  GLU A CA  1 
ATOM   892  C C   . GLU A 1 232 ? 132.774 143.287 123.897 1.00 245.05 ?  232  GLU A C   1 
ATOM   893  O O   . GLU A 1 232 ? 131.849 144.098 123.905 1.00 245.05 ?  232  GLU A O   1 
ATOM   894  C CB  . GLU A 1 232 ? 132.062 141.957 125.865 1.00 245.05 ?  232  GLU A CB  1 
ATOM   895  C CG  . GLU A 1 232 ? 131.991 142.298 127.343 1.00 245.05 ?  232  GLU A CG  1 
ATOM   896  C CD  . GLU A 1 232 ? 132.334 141.109 128.199 1.00 245.05 ?  232  GLU A CD  1 
ATOM   897  O OE1 . GLU A 1 232 ? 132.419 141.250 129.436 1.00 245.05 ?  232  GLU A OE1 1 
ATOM   898  O OE2 . GLU A 1 232 ? 132.528 140.030 127.611 1.00 245.05 -1 232  GLU A OE2 1 
ATOM   899  N N   . GLY A 1 233 ? 133.409 142.933 122.789 1.00 234.26 ?  233  GLY A N   1 
ATOM   900  C CA  . GLY A 1 233 ? 133.097 143.588 121.539 1.00 234.26 ?  233  GLY A CA  1 
ATOM   901  C C   . GLY A 1 233 ? 134.406 144.019 120.931 1.00 234.26 ?  233  GLY A C   1 
ATOM   902  O O   . GLY A 1 233 ? 134.746 143.582 119.848 1.00 234.26 ?  233  GLY A O   1 
ATOM   903  N N   . PRO A 1 234 ? 135.140 144.912 121.608 1.00 242.17 ?  234  PRO A N   1 
ATOM   904  C CA  . PRO A 1 234 ? 136.467 145.234 121.081 1.00 242.17 ?  234  PRO A CA  1 
ATOM   905  C C   . PRO A 1 234 ? 137.445 144.084 121.279 1.00 242.17 ?  234  PRO A C   1 
ATOM   906  O O   . PRO A 1 234 ? 138.332 143.921 120.450 1.00 242.17 ?  234  PRO A O   1 
ATOM   907  C CB  . PRO A 1 234 ? 136.882 146.438 121.918 1.00 242.17 ?  234  PRO A CB  1 
ATOM   908  C CG  . PRO A 1 234 ? 135.601 147.098 122.263 1.00 242.17 ?  234  PRO A CG  1 
ATOM   909  C CD  . PRO A 1 234 ? 134.638 145.973 122.497 1.00 242.17 ?  234  PRO A CD  1 
ATOM   910  N N   . PHE A 1 235 ? 137.301 143.311 122.351 1.00 250.74 ?  235  PHE A N   1 
ATOM   911  C CA  . PHE A 1 235 ? 138.154 142.141 122.555 1.00 250.74 ?  235  PHE A CA  1 
ATOM   912  C C   . PHE A 1 235 ? 138.013 141.298 121.316 1.00 250.74 ?  235  PHE A C   1 
ATOM   913  O O   . PHE A 1 235 ? 138.998 140.809 120.790 1.00 250.74 ?  235  PHE A O   1 
ATOM   914  C CB  . PHE A 1 235 ? 137.735 141.359 123.789 1.00 250.74 ?  235  PHE A CB  1 
ATOM   915  C CG  . PHE A 1 235 ? 138.504 141.728 125.016 1.00 250.74 ?  235  PHE A CG  1 
ATOM   916  C CD1 . PHE A 1 235 ? 138.633 143.049 125.396 1.00 250.74 ?  235  PHE A CD1 1 
ATOM   917  C CD2 . PHE A 1 235 ? 139.106 140.760 125.783 1.00 250.74 ?  235  PHE A CD2 1 
ATOM   918  C CE1 . PHE A 1 235 ? 139.340 143.399 126.527 1.00 250.74 ?  235  PHE A CE1 1 
ATOM   919  C CE2 . PHE A 1 235 ? 139.809 141.104 126.915 1.00 250.74 ?  235  PHE A CE2 1 
ATOM   920  C CZ  . PHE A 1 235 ? 139.933 142.422 127.288 1.00 250.74 ?  235  PHE A CZ  1 
ATOM   921  N N   . VAL A 1 236 ? 136.789 141.078 120.870 1.00 259.83 ?  236  VAL A N   1 
ATOM   922  C CA  . VAL A 1 236 ? 136.593 140.397 119.564 1.00 259.83 ?  236  VAL A CA  1 
ATOM   923  C C   . VAL A 1 236 ? 136.853 141.378 118.446 1.00 259.83 ?  236  VAL A C   1 
ATOM   924  O O   . VAL A 1 236 ? 135.937 142.064 117.971 1.00 259.83 ?  236  VAL A O   1 
ATOM   925  C CB  . VAL A 1 236 ? 135.437 139.362 119.180 1.00 259.83 ?  236  VAL A CB  1 
ATOM   926  C CG1 . VAL A 1 236 ? 133.931 139.770 119.145 1.00 259.83 ?  236  VAL A CG1 1 
ATOM   927  C CG2 . VAL A 1 236 ? 135.730 139.030 117.731 1.00 259.83 ?  236  VAL A CG2 1 
ATOM   928  N N   . HIS A 1 237 ? 138.117 141.529 118.112 1.00 254.65 ?  237  HIS A N   1 
ATOM   929  C CA  . HIS A 1 237 ? 138.539 142.345 116.999 1.00 254.65 ?  237  HIS A CA  1 
ATOM   930  C C   . HIS A 1 237 ? 139.953 142.137 117.401 1.00 254.65 ?  237  HIS A C   1 
ATOM   931  O O   . HIS A 1 237 ? 140.729 141.655 116.628 1.00 254.65 ?  237  HIS A O   1 
ATOM   932  C CB  . HIS A 1 237 ? 138.265 143.835 117.041 1.00 254.65 ?  237  HIS A CB  1 
ATOM   933  C CG  . HIS A 1 237 ? 138.965 144.564 115.940 1.00 254.65 ?  237  HIS A CG  1 
ATOM   934  N ND1 . HIS A 1 237 ? 139.334 145.884 116.024 1.00 254.65 ?  237  HIS A ND1 1 
ATOM   935  C CD2 . HIS A 1 237 ? 139.404 144.131 114.735 1.00 254.65 ?  237  HIS A CD2 1 
ATOM   936  C CE1 . HIS A 1 237 ? 139.960 146.242 114.920 1.00 254.65 ?  237  HIS A CE1 1 
ATOM   937  N NE2 . HIS A 1 237 ? 140.013 145.195 114.119 1.00 254.65 ?  237  HIS A NE2 1 
ATOM   938  N N   . ILE A 1 238 ? 140.276 142.457 118.647 1.00 265.51 ?  238  ILE A N   1 
ATOM   939  C CA  . ILE A 1 238 ? 141.612 142.203 119.151 1.00 265.51 ?  238  ILE A CA  1 
ATOM   940  C C   . ILE A 1 238 ? 141.894 140.715 118.942 1.00 265.51 ?  238  ILE A C   1 
ATOM   941  O O   . ILE A 1 238 ? 142.984 140.360 118.515 1.00 265.51 ?  238  ILE A O   1 
ATOM   942  C CB  . ILE A 1 238 ? 141.762 142.644 120.628 1.00 265.51 ?  238  ILE A CB  1 
ATOM   943  C CG1 . ILE A 1 238 ? 142.219 144.094 120.696 1.00 265.51 ?  238  ILE A CG1 1 
ATOM   944  C CG2 . ILE A 1 238 ? 142.695 141.742 121.424 1.00 265.51 ?  238  ILE A CG2 1 
ATOM   945  C CD1 . ILE A 1 238 ? 141.580 144.856 121.831 1.00 265.51 ?  238  ILE A CD1 1 
ATOM   946  N N   . ALA A 1 239 ? 140.900 139.855 119.172 1.00 245.47 ?  239  ALA A N   1 
ATOM   947  C CA  . ALA A 1 239 ? 141.153 138.441 118.991 1.00 245.47 ?  239  ALA A CA  1 
ATOM   948  C C   . ALA A 1 239 ? 141.148 138.032 117.541 1.00 245.47 ?  239  ALA A C   1 
ATOM   949  O O   . ALA A 1 239 ? 141.790 137.063 117.180 1.00 245.47 ?  239  ALA A O   1 
ATOM   950  C CB  . ALA A 1 239 ? 140.144 137.637 119.759 1.00 245.47 ?  239  ALA A CB  1 
ATOM   951  N N   . SER A 1 240 ? 140.426 138.761 116.705 1.00 275.90 ?  240  SER A N   1 
ATOM   952  C CA  . SER A 1 240 ? 140.430 138.477 115.282 1.00 275.90 ?  240  SER A CA  1 
ATOM   953  C C   . SER A 1 240 ? 141.696 139.019 114.637 1.00 275.90 ?  240  SER A C   1 
ATOM   954  O O   . SER A 1 240 ? 142.199 138.432 113.688 1.00 275.90 ?  240  SER A O   1 
ATOM   955  C CB  . SER A 1 240 ? 139.186 139.051 114.629 1.00 275.90 ?  240  SER A CB  1 
ATOM   956  O OG  . SER A 1 240 ? 138.040 138.302 114.992 1.00 275.90 ?  240  SER A OG  1 
ATOM   957  N N   . ILE A 1 241 ? 142.231 140.128 115.145 1.00 272.13 ?  241  ILE A N   1 
ATOM   958  C CA  . ILE A 1 241 ? 143.502 140.621 114.628 1.00 272.13 ?  241  ILE A CA  1 
ATOM   959  C C   . ILE A 1 241 ? 144.526 139.603 115.048 1.00 272.13 ?  241  ILE A C   1 
ATOM   960  O O   . ILE A 1 241 ? 145.327 139.153 114.246 1.00 272.13 ?  241  ILE A O   1 
ATOM   961  C CB  . ILE A 1 241 ? 143.932 141.970 115.224 1.00 272.13 ?  241  ILE A CB  1 
ATOM   962  C CG1 . ILE A 1 241 ? 142.940 143.070 114.889 1.00 272.13 ?  241  ILE A CG1 1 
ATOM   963  C CG2 . ILE A 1 241 ? 145.296 142.374 114.695 1.00 272.13 ?  241  ILE A CG2 1 
ATOM   964  C CD1 . ILE A 1 241 ? 142.883 144.145 115.945 1.00 272.13 ?  241  ILE A CD1 1 
ATOM   965  N N   . CYS A 1 242 ? 144.478 139.209 116.313 1.00 298.43 ?  242  CYS A N   1 
ATOM   966  C CA  . CYS A 1 242 ? 145.422 138.230 116.812 1.00 298.43 ?  242  CYS A CA  1 
ATOM   967  C C   . CYS A 1 242 ? 145.330 136.943 116.025 1.00 298.43 ?  242  CYS A C   1 
ATOM   968  O O   . CYS A 1 242 ? 146.346 136.358 115.708 1.00 298.43 ?  242  CYS A O   1 
ATOM   969  C CB  . CYS A 1 242 ? 145.189 137.970 118.290 1.00 298.43 ?  242  CYS A CB  1 
ATOM   970  S SG  . CYS A 1 242 ? 146.674 138.044 119.310 1.00 298.43 ?  242  CYS A SG  1 
ATOM   971  N N   . ALA A 1 243 ? 144.123 136.507 115.688 1.00 278.91 ?  243  ALA A N   1 
ATOM   972  C CA  . ALA A 1 243 ? 143.960 135.311 114.874 1.00 278.91 ?  243  ALA A CA  1 
ATOM   973  C C   . ALA A 1 243 ? 144.636 135.472 113.532 1.00 278.91 ?  243  ALA A C   1 
ATOM   974  O O   . ALA A 1 243 ? 145.387 134.606 113.119 1.00 278.91 ?  243  ALA A O   1 
ATOM   975  C CB  . ALA A 1 243 ? 142.492 134.979 114.694 1.00 278.91 ?  243  ALA A CB  1 
ATOM   976  N N   . ALA A 1 244 ? 144.383 136.584 112.851 1.00 296.98 ?  244  ALA A N   1 
ATOM   977  C CA  . ALA A 1 244 ? 145.007 136.838 111.560 1.00 296.98 ?  244  ALA A CA  1 
ATOM   978  C C   . ALA A 1 244 ? 146.522 136.859 111.664 1.00 296.98 ?  244  ALA A C   1 
ATOM   979  O O   . ALA A 1 244 ? 147.208 136.244 110.855 1.00 296.98 ?  244  ALA A O   1 
ATOM   980  C CB  . ALA A 1 244 ? 144.503 138.148 110.990 1.00 296.98 ?  244  ALA A CB  1 
ATOM   981  N N   . VAL A 1 245 ? 147.048 137.560 112.658 1.00 291.00 ?  245  VAL A N   1 
ATOM   982  C CA  . VAL A 1 245 ? 148.489 137.635 112.852 1.00 291.00 ?  245  VAL A CA  1 
ATOM   983  C C   . VAL A 1 245 ? 149.063 136.258 113.153 1.00 291.00 ?  245  VAL A C   1 
ATOM   984  O O   . VAL A 1 245 ? 150.036 135.847 112.536 1.00 291.00 ?  245  VAL A O   1 
ATOM   985  C CB  . VAL A 1 245 ? 148.832 138.637 113.970 1.00 291.00 ?  245  VAL A CB  1 
ATOM   986  C CG1 . VAL A 1 245 ? 150.292 138.537 114.387 1.00 291.00 ?  245  VAL A CG1 1 
ATOM   987  C CG2 . VAL A 1 245 ? 148.513 140.051 113.514 1.00 291.00 ?  245  VAL A CG2 1 
ATOM   988  N N   . LEU A 1 246 ? 148.442 135.526 114.073 1.00 301.56 ?  246  LEU A N   1 
ATOM   989  C CA  . LEU A 1 246 ? 148.912 134.187 114.412 1.00 301.56 ?  246  LEU A CA  1 
ATOM   990  C C   . LEU A 1 246 ? 148.883 133.287 113.196 1.00 301.56 ?  246  LEU A C   1 
ATOM   991  O O   . LEU A 1 246 ? 149.812 132.525 112.971 1.00 301.56 ?  246  LEU A O   1 
ATOM   992  C CB  . LEU A 1 246 ? 148.076 133.574 115.533 1.00 301.56 ?  246  LEU A CB  1 
ATOM   993  C CG  . LEU A 1 246 ? 148.737 133.514 116.910 1.00 301.56 ?  246  LEU A CG  1 
ATOM   994  C CD1 . LEU A 1 246 ? 150.077 134.228 116.912 1.00 301.56 ?  246  LEU A CD1 1 
ATOM   995  C CD2 . LEU A 1 246 ? 147.833 134.100 117.978 1.00 301.56 ?  246  LEU A CD2 1 
ATOM   996  N N   . SER A 1 247 ? 147.829 133.384 112.396 1.00 308.97 ?  247  SER A N   1 
ATOM   997  C CA  . SER A 1 247 ? 147.733 132.579 111.187 1.00 308.97 ?  247  SER A CA  1 
ATOM   998  C C   . SER A 1 247 ? 148.897 132.864 110.255 1.00 308.97 ?  247  SER A C   1 
ATOM   999  O O   . SER A 1 247 ? 149.497 131.945 109.725 1.00 308.97 ?  247  SER A O   1 
ATOM   1000 C CB  . SER A 1 247 ? 146.402 132.817 110.474 1.00 308.97 ?  247  SER A CB  1 
ATOM   1001 O OG  . SER A 1 247 ? 146.597 133.337 109.172 1.00 308.97 ?  247  SER A OG  1 
ATOM   1002 N N   . LYS A 1 248 ? 149.230 134.135 110.065 1.00 305.64 ?  248  LYS A N   1 
ATOM   1003 C CA  . LYS A 1 248 ? 150.345 134.489 109.199 1.00 305.64 ?  248  LYS A CA  1 
ATOM   1004 C C   . LYS A 1 248 ? 151.646 133.998 109.786 1.00 305.64 ?  248  LYS A C   1 
ATOM   1005 O O   . LYS A 1 248 ? 152.419 133.339 109.104 1.00 305.64 ?  248  LYS A O   1 
ATOM   1006 C CB  . LYS A 1 248 ? 150.401 135.994 108.986 1.00 305.64 ?  248  LYS A CB  1 
ATOM   1007 C CG  . LYS A 1 248 ? 149.315 136.517 108.069 1.00 305.64 ?  248  LYS A CG  1 
ATOM   1008 C CD  . LYS A 1 248 ? 149.631 137.927 107.603 1.00 305.64 ?  248  LYS A CD  1 
ATOM   1009 C CE  . LYS A 1 248 ? 150.380 137.911 106.281 1.00 305.64 ?  248  LYS A CE  1 
ATOM   1010 N NZ  . LYS A 1 248 ? 151.761 138.451 106.414 1.00 305.64 1  248  LYS A NZ  1 
ATOM   1011 N N   . PHE A 1 249 ? 151.879 134.286 111.060 1.00 306.46 ?  249  PHE A N   1 
ATOM   1012 C CA  . PHE A 1 249 ? 153.102 133.849 111.732 1.00 306.46 ?  249  PHE A CA  1 
ATOM   1013 C C   . PHE A 1 249 ? 153.316 132.346 111.582 1.00 306.46 ?  249  PHE A C   1 
ATOM   1014 O O   . PHE A 1 249 ? 154.440 131.891 111.401 1.00 306.46 ?  249  PHE A O   1 
ATOM   1015 C CB  . PHE A 1 249 ? 153.084 134.320 113.203 1.00 306.46 ?  249  PHE A CB  1 
ATOM   1016 C CG  . PHE A 1 249 ? 153.548 133.294 114.205 1.00 306.46 ?  249  PHE A CG  1 
ATOM   1017 C CD1 . PHE A 1 249 ? 154.894 133.144 114.496 1.00 306.46 ?  249  PHE A CD1 1 
ATOM   1018 C CD2 . PHE A 1 249 ? 152.631 132.512 114.893 1.00 306.46 ?  249  PHE A CD2 1 
ATOM   1019 C CE1 . PHE A 1 249 ? 155.318 132.208 115.419 1.00 306.46 ?  249  PHE A CE1 1 
ATOM   1020 C CE2 . PHE A 1 249 ? 153.048 131.578 115.818 1.00 306.46 ?  249  PHE A CE2 1 
ATOM   1021 C CZ  . PHE A 1 249 ? 154.394 131.427 116.084 1.00 306.46 ?  249  PHE A CZ  1 
ATOM   1022 N N   . MET A 1 250 ? 152.243 131.573 111.641 1.00 308.01 ?  250  MET A N   1 
ATOM   1023 C CA  . MET A 1 250 ? 152.361 130.138 111.501 1.00 308.01 ?  250  MET A CA  1 
ATOM   1024 C C   . MET A 1 250 ? 152.418 129.723 110.046 1.00 308.01 ?  250  MET A C   1 
ATOM   1025 O O   . MET A 1 250 ? 153.464 129.300 109.561 1.00 308.01 ?  250  MET A O   1 
ATOM   1026 C CB  . MET A 1 250 ? 151.180 129.454 112.179 1.00 308.01 ?  250  MET A CB  1 
ATOM   1027 C CG  . MET A 1 250 ? 151.582 128.404 113.192 1.00 308.01 ?  250  MET A CG  1 
ATOM   1028 S SD  . MET A 1 250 ? 150.215 128.036 114.296 1.00 308.01 ?  250  MET A SD  1 
ATOM   1029 C CE  . MET A 1 250 ? 149.914 129.656 114.990 1.00 308.01 ?  250  MET A CE  1 
ATOM   1030 N N   . SER A 1 251 ? 151.301 129.842 109.343 1.00 303.41 ?  251  SER A N   1 
ATOM   1031 C CA  . SER A 1 251 ? 151.235 129.392 107.954 1.00 303.41 ?  251  SER A CA  1 
ATOM   1032 C C   . SER A 1 251 ? 152.173 130.099 106.991 1.00 303.41 ?  251  SER A C   1 
ATOM   1033 O O   . SER A 1 251 ? 153.044 129.462 106.399 1.00 303.41 ?  251  SER A O   1 
ATOM   1034 C CB  . SER A 1 251 ? 149.796 129.488 107.437 1.00 303.41 ?  251  SER A CB  1 
ATOM   1035 O OG  . SER A 1 251 ? 149.766 129.606 106.025 1.00 303.41 ?  251  SER A OG  1 
ATOM   1036 N N   . VAL A 1 252 ? 152.010 131.406 106.817 1.00 294.29 ?  252  VAL A N   1 
ATOM   1037 C CA  . VAL A 1 252 ? 152.824 132.105 105.817 1.00 294.29 ?  252  VAL A CA  1 
ATOM   1038 C C   . VAL A 1 252 ? 154.284 132.309 106.235 1.00 294.29 ?  252  VAL A C   1 
ATOM   1039 O O   . VAL A 1 252 ? 155.159 132.448 105.380 1.00 294.29 ?  252  VAL A O   1 
ATOM   1040 C CB  . VAL A 1 252 ? 152.130 133.391 105.291 1.00 294.29 ?  252  VAL A CB  1 
ATOM   1041 C CG1 . VAL A 1 252 ? 150.625 133.301 105.489 1.00 294.29 ?  252  VAL A CG1 1 
ATOM   1042 C CG2 . VAL A 1 252 ? 152.685 134.654 105.922 1.00 294.29 ?  252  VAL A CG2 1 
ATOM   1043 N N   . PHE A 1 253 ? 154.563 132.285 107.533 1.00 291.46 ?  253  PHE A N   1 
ATOM   1044 C CA  . PHE A 1 253 ? 155.945 132.393 107.989 1.00 291.46 ?  253  PHE A CA  1 
ATOM   1045 C C   . PHE A 1 253 ? 156.367 131.086 108.647 1.00 291.46 ?  253  PHE A C   1 
ATOM   1046 O O   . PHE A 1 253 ? 156.928 131.082 109.741 1.00 291.46 ?  253  PHE A O   1 
ATOM   1047 C CB  . PHE A 1 253 ? 156.123 133.562 108.960 1.00 291.46 ?  253  PHE A CB  1 
ATOM   1048 C CG  . PHE A 1 253 ? 155.762 134.897 108.379 1.00 291.46 ?  253  PHE A CG  1 
ATOM   1049 C CD1 . PHE A 1 253 ? 156.349 135.340 107.207 1.00 291.46 ?  253  PHE A CD1 1 
ATOM   1050 C CD2 . PHE A 1 253 ? 154.844 135.716 109.012 1.00 291.46 ?  253  PHE A CD2 1 
ATOM   1051 C CE1 . PHE A 1 253 ? 156.018 136.570 106.671 1.00 291.46 ?  253  PHE A CE1 1 
ATOM   1052 C CE2 . PHE A 1 253 ? 154.506 136.944 108.484 1.00 291.46 ?  253  PHE A CE2 1 
ATOM   1053 C CZ  . PHE A 1 253 ? 155.096 137.373 107.312 1.00 291.46 ?  253  PHE A CZ  1 
ATOM   1054 N N   . TYR A 1 262 ? 139.893 128.716 106.139 1.00 316.42 ?  262  TYR A N   1 
ATOM   1055 C CA  . TYR A 1 262 ? 139.920 129.994 105.436 1.00 316.42 ?  262  TYR A CA  1 
ATOM   1056 C C   . TYR A 1 262 ? 139.758 131.155 106.404 1.00 316.42 ?  262  TYR A C   1 
ATOM   1057 O O   . TYR A 1 262 ? 139.751 130.957 107.614 1.00 316.42 ?  262  TYR A O   1 
ATOM   1058 C CB  . TYR A 1 262 ? 138.852 130.049 104.335 1.00 316.42 ?  262  TYR A CB  1 
ATOM   1059 C CG  . TYR A 1 262 ? 137.567 129.306 104.636 1.00 316.42 ?  262  TYR A CG  1 
ATOM   1060 C CD1 . TYR A 1 262 ? 136.519 129.934 105.287 1.00 316.42 ?  262  TYR A CD1 1 
ATOM   1061 C CD2 . TYR A 1 262 ? 137.390 127.984 104.236 1.00 316.42 ?  262  TYR A CD2 1 
ATOM   1062 C CE1 . TYR A 1 262 ? 135.340 129.268 105.552 1.00 316.42 ?  262  TYR A CE1 1 
ATOM   1063 C CE2 . TYR A 1 262 ? 136.217 127.308 104.505 1.00 316.42 ?  262  TYR A CE2 1 
ATOM   1064 C CZ  . TYR A 1 262 ? 135.195 127.955 105.162 1.00 316.42 ?  262  TYR A CZ  1 
ATOM   1065 O OH  . TYR A 1 262 ? 134.022 127.292 105.431 1.00 316.42 ?  262  TYR A OH  1 
ATOM   1066 N N   . TYR A 1 263 ? 139.615 132.367 105.879 1.00 309.96 ?  263  TYR A N   1 
ATOM   1067 C CA  . TYR A 1 263 ? 139.514 133.540 106.741 1.00 309.96 ?  263  TYR A CA  1 
ATOM   1068 C C   . TYR A 1 263 ? 138.330 133.485 107.685 1.00 309.96 ?  263  TYR A C   1 
ATOM   1069 O O   . TYR A 1 263 ? 138.468 133.789 108.861 1.00 309.96 ?  263  TYR A O   1 
ATOM   1070 C CB  . TYR A 1 263 ? 139.448 134.823 105.919 1.00 309.96 ?  263  TYR A CB  1 
ATOM   1071 C CG  . TYR A 1 263 ? 140.382 135.899 106.419 1.00 309.96 ?  263  TYR A CG  1 
ATOM   1072 C CD1 . TYR A 1 263 ? 141.403 135.596 107.312 1.00 309.96 ?  263  TYR A CD1 1 
ATOM   1073 C CD2 . TYR A 1 263 ? 140.247 137.216 106.000 1.00 309.96 ?  263  TYR A CD2 1 
ATOM   1074 C CE1 . TYR A 1 263 ? 142.261 136.574 107.774 1.00 309.96 ?  263  TYR A CE1 1 
ATOM   1075 C CE2 . TYR A 1 263 ? 141.102 138.200 106.455 1.00 309.96 ?  263  TYR A CE2 1 
ATOM   1076 C CZ  . TYR A 1 263 ? 142.106 137.873 107.341 1.00 309.96 ?  263  TYR A CZ  1 
ATOM   1077 O OH  . TYR A 1 263 ? 142.961 138.849 107.794 1.00 309.96 ?  263  TYR A OH  1 
ATOM   1078 N N   . SER A 1 264 ? 137.166 133.104 107.174 1.00 293.58 ?  264  SER A N   1 
ATOM   1079 C CA  . SER A 1 264 ? 135.989 132.998 108.020 1.00 293.58 ?  264  SER A CA  1 
ATOM   1080 C C   . SER A 1 264 ? 136.242 132.073 109.192 1.00 293.58 ?  264  SER A C   1 
ATOM   1081 O O   . SER A 1 264 ? 135.948 132.430 110.318 1.00 293.58 ?  264  SER A O   1 
ATOM   1082 C CB  . SER A 1 264 ? 134.773 132.528 107.228 1.00 293.58 ?  264  SER A CB  1 
ATOM   1083 O OG  . SER A 1 264 ? 133.924 133.612 106.898 1.00 293.58 ?  264  SER A OG  1 
ATOM   1084 N N   . ASP A 1 265 ? 136.799 130.895 108.934 1.00 302.56 ?  265  ASP A N   1 
ATOM   1085 C CA  . ASP A 1 265 ? 137.105 129.951 110.001 1.00 302.56 ?  265  ASP A CA  1 
ATOM   1086 C C   . ASP A 1 265 ? 137.992 130.588 111.038 1.00 302.56 ?  265  ASP A C   1 
ATOM   1087 O O   . ASP A 1 265 ? 137.672 130.571 112.223 1.00 302.56 ?  265  ASP A O   1 
ATOM   1088 C CB  . ASP A 1 265 ? 137.816 128.728 109.431 1.00 302.56 ?  265  ASP A CB  1 
ATOM   1089 C CG  . ASP A 1 265 ? 136.911 127.875 108.582 1.00 302.56 ?  265  ASP A CG  1 
ATOM   1090 O OD1 . ASP A 1 265 ? 135.687 128.108 108.612 1.00 302.56 ?  265  ASP A OD1 1 
ATOM   1091 O OD2 . ASP A 1 265 ? 137.419 126.974 107.886 1.00 302.56 -1 265  ASP A OD2 1 
ATOM   1092 N N   . ILE A 1 266 ? 139.102 131.169 110.595 1.00 288.36 ?  266  ILE A N   1 
ATOM   1093 C CA  . ILE A 1 266 ? 140.043 131.815 111.507 1.00 288.36 ?  266  ILE A CA  1 
ATOM   1094 C C   . ILE A 1 266 ? 139.361 132.863 112.376 1.00 288.36 ?  266  ILE A C   1 
ATOM   1095 O O   . ILE A 1 266 ? 139.406 132.780 113.600 1.00 288.36 ?  266  ILE A O   1 
ATOM   1096 C CB  . ILE A 1 266 ? 141.215 132.433 110.714 1.00 288.36 ?  266  ILE A CB  1 
ATOM   1097 C CG1 . ILE A 1 266 ? 142.155 131.332 110.225 1.00 288.36 ?  266  ILE A CG1 1 
ATOM   1098 C CG2 . ILE A 1 266 ? 141.990 133.440 111.540 1.00 288.36 ?  266  ILE A CG2 1 
ATOM   1099 C CD1 . ILE A 1 266 ? 142.900 131.690 108.958 1.00 288.36 ?  266  ILE A CD1 1 
ATOM   1100 N N   . LEU A 1 267 ? 138.688 133.822 111.756 1.00 268.67 ?  267  LEU A N   1 
ATOM   1101 C CA  . LEU A 1 267 ? 138.068 134.900 112.516 1.00 268.67 ?  267  LEU A CA  1 
ATOM   1102 C C   . LEU A 1 267 ? 136.845 134.476 113.316 1.00 268.67 ?  267  LEU A C   1 
ATOM   1103 O O   . LEU A 1 267 ? 136.461 135.168 114.248 1.00 268.67 ?  267  LEU A O   1 
ATOM   1104 C CB  . LEU A 1 267 ? 137.733 136.073 111.598 1.00 268.67 ?  267  LEU A CB  1 
ATOM   1105 C CG  . LEU A 1 267 ? 138.862 136.481 110.650 1.00 268.67 ?  267  LEU A CG  1 
ATOM   1106 C CD1 . LEU A 1 267 ? 138.370 137.493 109.634 1.00 268.67 ?  267  LEU A CD1 1 
ATOM   1107 C CD2 . LEU A 1 267 ? 140.071 137.012 111.401 1.00 268.67 ?  267  LEU A CD2 1 
ATOM   1108 N N   . THR A 1 268 ? 136.228 133.353 112.968 1.00 265.95 ?  268  THR A N   1 
ATOM   1109 C CA  . THR A 1 268 ? 135.102 132.847 113.748 1.00 265.95 ?  268  THR A CA  1 
ATOM   1110 C C   . THR A 1 268 ? 135.639 132.297 115.055 1.00 265.95 ?  268  THR A C   1 
ATOM   1111 O O   . THR A 1 268 ? 135.043 132.488 116.113 1.00 265.95 ?  268  THR A O   1 
ATOM   1112 C CB  . THR A 1 268 ? 134.330 131.749 112.989 1.00 30.00  ?  268  THR A CB  1 
ATOM   1113 O OG1 . THR A 1 268 ? 133.671 132.327 111.856 1.00 30.00  ?  268  THR A OG1 1 
ATOM   1114 C CG2 . THR A 1 268 ? 133.289 131.087 113.877 1.00 30.00  ?  268  THR A CG2 1 
ATOM   1115 N N   . VAL A 1 269 ? 136.781 131.622 114.991 1.00 271.98 ?  269  VAL A N   1 
ATOM   1116 C CA  . VAL A 1 269 ? 137.394 131.118 116.209 1.00 271.98 ?  269  VAL A CA  1 
ATOM   1117 C C   . VAL A 1 269 ? 137.923 132.313 116.974 1.00 271.98 ?  269  VAL A C   1 
ATOM   1118 O O   . VAL A 1 269 ? 137.853 132.351 118.201 1.00 271.98 ?  269  VAL A O   1 
ATOM   1119 C CB  . VAL A 1 269 ? 138.507 130.105 115.905 1.00 271.98 ?  269  VAL A CB  1 
ATOM   1120 C CG1 . VAL A 1 269 ? 139.206 129.675 117.183 1.00 271.98 ?  269  VAL A CG1 1 
ATOM   1121 C CG2 . VAL A 1 269 ? 137.912 128.893 115.211 1.00 271.98 ?  269  VAL A CG2 1 
ATOM   1122 N N   . GLY A 1 270 ? 138.420 133.312 116.250 1.00 274.45 ?  270  GLY A N   1 
ATOM   1123 C CA  . GLY A 1 270 ? 138.887 134.523 116.903 1.00 274.45 ?  270  GLY A CA  1 
ATOM   1124 C C   . GLY A 1 270 ? 137.739 135.128 117.680 1.00 274.45 ?  270  GLY A C   1 
ATOM   1125 O O   . GLY A 1 270 ? 137.918 135.582 118.800 1.00 274.45 ?  270  GLY A O   1 
ATOM   1126 N N   . CYS A 1 271 ? 136.543 135.118 117.106 1.00 276.29 ?  271  CYS A N   1 
ATOM   1127 C CA  . CYS A 1 271 ? 135.376 135.622 117.818 1.00 276.29 ?  271  CYS A CA  1 
ATOM   1128 C C   . CYS A 1 271 ? 135.123 134.834 119.085 1.00 276.29 ?  271  CYS A C   1 
ATOM   1129 O O   . CYS A 1 271 ? 134.909 135.414 120.143 1.00 276.29 ?  271  CYS A O   1 
ATOM   1130 C CB  . CYS A 1 271 ? 134.129 135.588 116.931 1.00 276.29 ?  271  CYS A CB  1 
ATOM   1131 S SG  . CYS A 1 271 ? 134.078 136.799 115.589 1.00 276.29 ?  271  CYS A SG  1 
ATOM   1132 N N   . ALA A 1 272 ? 135.156 133.511 118.987 1.00 296.18 ?  272  ALA A N   1 
ATOM   1133 C CA  . ALA A 1 272 ? 134.916 132.660 120.145 1.00 296.18 ?  272  ALA A CA  1 
ATOM   1134 C C   . ALA A 1 272 ? 135.876 132.958 121.268 1.00 296.18 ?  272  ALA A C   1 
ATOM   1135 O O   . ALA A 1 272 ? 135.461 133.120 122.409 1.00 296.18 ?  272  ALA A O   1 
ATOM   1136 C CB  . ALA A 1 272 ? 135.020 131.202 119.749 1.00 296.18 ?  272  ALA A CB  1 
ATOM   1137 N N   . VAL A 1 273 ? 137.163 133.034 120.952 1.00 306.83 ?  273  VAL A N   1 
ATOM   1138 C CA  . VAL A 1 273 ? 138.160 133.266 121.987 1.00 306.83 ?  273  VAL A CA  1 
ATOM   1139 C C   . VAL A 1 273 ? 138.141 134.700 122.479 1.00 306.83 ?  273  VAL A C   1 
ATOM   1140 O O   . VAL A 1 273 ? 138.501 134.958 123.611 1.00 306.83 ?  273  VAL A O   1 
ATOM   1141 C CB  . VAL A 1 273 ? 139.571 132.842 121.544 1.00 306.83 ?  273  VAL A CB  1 
ATOM   1142 C CG1 . VAL A 1 273 ? 139.524 131.441 120.984 1.00 306.83 ?  273  VAL A CG1 1 
ATOM   1143 C CG2 . VAL A 1 273 ? 140.132 133.795 120.509 1.00 306.83 ?  273  VAL A CG2 1 
ATOM   1144 N N   . GLY A 1 274 ? 137.697 135.634 121.649 1.00 284.31 ?  274  GLY A N   1 
ATOM   1145 C CA  . GLY A 1 274 ? 137.582 137.007 122.088 1.00 284.31 ?  274  GLY A CA  1 
ATOM   1146 C C   . GLY A 1 274 ? 136.565 137.086 123.190 1.00 284.31 ?  274  GLY A C   1 
ATOM   1147 O O   . GLY A 1 274 ? 136.859 137.564 124.283 1.00 284.31 ?  274  GLY A O   1 
ATOM   1148 N N   . VAL A 1 275 ? 135.364 136.595 122.918 1.00 263.92 ?  275  VAL A N   1 
ATOM   1149 C CA  . VAL A 1 275 ? 134.322 136.608 123.929 1.00 263.92 ?  275  VAL A CA  1 
ATOM   1150 C C   . VAL A 1 275 ? 134.727 135.735 125.106 1.00 263.92 ?  275  VAL A C   1 
ATOM   1151 O O   . VAL A 1 275 ? 134.600 136.144 126.252 1.00 263.92 ?  275  VAL A O   1 
ATOM   1152 C CB  . VAL A 1 275 ? 132.968 136.156 123.359 1.00 263.92 ?  275  VAL A CB  1 
ATOM   1153 C CG1 . VAL A 1 275 ? 131.857 136.449 124.352 1.00 263.92 ?  275  VAL A CG1 1 
ATOM   1154 C CG2 . VAL A 1 275 ? 132.687 136.864 122.044 1.00 263.92 ?  275  VAL A CG2 1 
ATOM   1155 N N   . GLY A 1 276 ? 135.252 134.550 124.828 1.00 285.28 ?  276  GLY A N   1 
ATOM   1156 C CA  . GLY A 1 276 ? 135.670 133.655 125.889 1.00 285.28 ?  276  GLY A CA  1 
ATOM   1157 C C   . GLY A 1 276 ? 136.707 134.236 126.823 1.00 285.28 ?  276  GLY A C   1 
ATOM   1158 O O   . GLY A 1 276 ? 136.580 134.107 128.036 1.00 285.28 ?  276  GLY A O   1 
ATOM   1159 N N   . CYS A 1 277 ? 137.731 134.882 126.277 1.00 314.53 ?  277  CYS A N   1 
ATOM   1160 C CA  . CYS A 1 277 ? 138.812 135.403 127.110 1.00 314.53 ?  277  CYS A CA  1 
ATOM   1161 C C   . CYS A 1 277 ? 138.460 136.710 127.795 1.00 314.53 ?  277  CYS A C   1 
ATOM   1162 O O   . CYS A 1 277 ? 139.089 137.072 128.781 1.00 314.53 ?  277  CYS A O   1 
ATOM   1163 C CB  . CYS A 1 277 ? 140.093 135.571 126.292 1.00 314.53 ?  277  CYS A CB  1 
ATOM   1164 S SG  . CYS A 1 277 ? 140.204 137.146 125.417 1.00 314.53 ?  277  CYS A SG  1 
ATOM   1165 N N   . CYS A 1 278 ? 137.469 137.421 127.279 1.00 274.97 ?  278  CYS A N   1 
ATOM   1166 C CA  . CYS A 1 278 ? 137.048 138.679 127.877 1.00 274.97 ?  278  CYS A CA  1 
ATOM   1167 C C   . CYS A 1 278 ? 136.759 138.505 129.347 1.00 274.97 ?  278  CYS A C   1 
ATOM   1168 O O   . CYS A 1 278 ? 137.516 138.965 130.202 1.00 274.97 ?  278  CYS A O   1 
ATOM   1169 C CB  . CYS A 1 278 ? 135.765 139.133 127.196 1.00 274.97 ?  278  CYS A CB  1 
ATOM   1170 S SG  . CYS A 1 278 ? 135.616 140.905 126.973 1.00 274.97 ?  278  CYS A SG  1 
ATOM   1171 N N   . PHE A 1 279 ? 135.644 137.847 129.646 1.00 227.42 ?  279  PHE A N   1 
ATOM   1172 C CA  . PHE A 1 279 ? 135.219 137.659 131.035 1.00 227.42 ?  279  PHE A CA  1 
ATOM   1173 C C   . PHE A 1 279 ? 135.504 136.311 131.646 1.00 227.42 ?  279  PHE A C   1 
ATOM   1174 O O   . PHE A 1 279 ? 135.284 136.125 132.839 1.00 227.42 ?  279  PHE A O   1 
ATOM   1175 C CB  . PHE A 1 279 ? 133.707 137.876 131.177 1.00 227.42 ?  279  PHE A CB  1 
ATOM   1176 C CG  . PHE A 1 279 ? 132.902 137.419 129.995 1.00 227.42 ?  279  PHE A CG  1 
ATOM   1177 C CD1 . PHE A 1 279 ? 133.219 136.269 129.294 1.00 227.42 ?  279  PHE A CD1 1 
ATOM   1178 C CD2 . PHE A 1 279 ? 131.797 138.130 129.610 1.00 227.42 ?  279  PHE A CD2 1 
ATOM   1179 C CE1 . PHE A 1 279 ? 132.477 135.874 128.210 1.00 227.42 ?  279  PHE A CE1 1 
ATOM   1180 C CE2 . PHE A 1 279 ? 131.060 137.751 128.511 1.00 227.42 ?  279  PHE A CE2 1 
ATOM   1181 C CZ  . PHE A 1 279 ? 131.401 136.618 127.812 1.00 227.42 ?  279  PHE A CZ  1 
ATOM   1182 N N   . GLY A 1 280 ? 135.961 135.355 130.855 1.00 219.72 ?  280  GLY A N   1 
ATOM   1183 C CA  . GLY A 1 280 ? 136.111 134.026 131.435 1.00 219.72 ?  280  GLY A CA  1 
ATOM   1184 C C   . GLY A 1 280 ? 134.850 133.209 131.255 1.00 219.72 ?  280  GLY A C   1 
ATOM   1185 O O   . GLY A 1 280 ? 134.267 132.770 132.246 1.00 219.72 ?  280  GLY A O   1 
ATOM   1186 N N   . THR A 1 281 ? 134.435 132.988 130.018 1.00 234.03 ?  281  THR A N   1 
ATOM   1187 C CA  . THR A 1 281 ? 133.211 132.257 129.672 1.00 234.03 ?  281  THR A CA  1 
ATOM   1188 C C   . THR A 1 281 ? 133.513 131.422 128.367 1.00 234.03 ?  281  THR A C   1 
ATOM   1189 O O   . THR A 1 281 ? 133.176 131.872 127.283 1.00 234.03 ?  281  THR A O   1 
ATOM   1190 C CB  . THR A 1 281 ? 131.882 132.985 129.776 1.00 234.03 ?  281  THR A CB  1 
ATOM   1191 O OG1 . THR A 1 281 ? 131.645 133.330 131.148 1.00 234.03 ?  281  THR A OG1 1 
ATOM   1192 C CG2 . THR A 1 281 ? 130.790 132.127 129.342 1.00 234.03 ?  281  THR A CG2 1 
ATOM   1193 N N   . PRO A 1 282 ? 134.224 130.238 128.466 1.00 231.49 ?  282  PRO A N   1 
ATOM   1194 C CA  . PRO A 1 282 ? 134.512 129.385 127.309 1.00 231.49 ?  282  PRO A CA  1 
ATOM   1195 C C   . PRO A 1 282 ? 133.248 129.043 126.520 1.00 231.49 ?  282  PRO A C   1 
ATOM   1196 O O   . PRO A 1 282 ? 133.111 129.535 125.415 1.00 231.49 ?  282  PRO A O   1 
ATOM   1197 C CB  . PRO A 1 282 ? 135.091 128.127 127.945 1.00 231.49 ?  282  PRO A CB  1 
ATOM   1198 C CG  . PRO A 1 282 ? 135.666 128.588 129.237 1.00 231.49 ?  282  PRO A CG  1 
ATOM   1199 C CD  . PRO A 1 282 ? 134.774 129.694 129.717 1.00 231.49 ?  282  PRO A CD  1 
ATOM   1200 N N   . LEU A 1 283 ? 132.345 128.237 127.075 1.00 229.79 ?  283  LEU A N   1 
ATOM   1201 C CA  . LEU A 1 283 ? 131.114 127.844 126.396 1.00 229.79 ?  283  LEU A CA  1 
ATOM   1202 C C   . LEU A 1 283 ? 130.309 129.039 125.925 1.00 229.79 ?  283  LEU A C   1 
ATOM   1203 O O   . LEU A 1 283 ? 130.017 129.150 124.739 1.00 229.79 ?  283  LEU A O   1 
ATOM   1204 C CB  . LEU A 1 283 ? 130.248 126.978 127.307 1.00 229.79 ?  283  LEU A CB  1 
ATOM   1205 C CG  . LEU A 1 283 ? 129.496 125.786 126.717 1.00 229.79 ?  283  LEU A CG  1 
ATOM   1206 C CD1 . LEU A 1 283 ? 129.204 124.773 127.811 1.00 229.79 ?  283  LEU A CD1 1 
ATOM   1207 C CD2 . LEU A 1 283 ? 128.215 126.184 125.999 1.00 229.79 ?  283  LEU A CD2 1 
ATOM   1208 N N   . GLY A 1 284 ? 129.924 129.912 126.853 1.00 243.51 ?  284  GLY A N   1 
ATOM   1209 C CA  . GLY A 1 284 ? 129.142 131.073 126.485 1.00 243.51 ?  284  GLY A CA  1 
ATOM   1210 C C   . GLY A 1 284 ? 129.789 131.873 125.387 1.00 243.51 ?  284  GLY A C   1 
ATOM   1211 O O   . GLY A 1 284 ? 129.098 132.338 124.504 1.00 243.51 ?  284  GLY A O   1 
ATOM   1212 N N   . GLY A 1 285 ? 131.106 132.038 125.433 1.00 256.46 ?  285  GLY A N   1 
ATOM   1213 C CA  . GLY A 1 285 ? 131.819 132.738 124.384 1.00 256.46 ?  285  GLY A CA  1 
ATOM   1214 C C   . GLY A 1 285 ? 131.719 132.118 123.012 1.00 256.46 ?  285  GLY A C   1 
ATOM   1215 O O   . GLY A 1 285 ? 131.462 132.808 122.040 1.00 256.46 ?  285  GLY A O   1 
ATOM   1216 N N   . VAL A 1 286 ? 131.920 130.813 122.915 1.00 248.56 ?  286  VAL A N   1 
ATOM   1217 C CA  . VAL A 1 286 ? 131.763 130.141 121.632 1.00 248.56 ?  286  VAL A CA  1 
ATOM   1218 C C   . VAL A 1 286 ? 130.337 130.304 121.146 1.00 248.56 ?  286  VAL A C   1 
ATOM   1219 O O   . VAL A 1 286 ? 130.113 130.717 120.022 1.00 248.56 ?  286  VAL A O   1 
ATOM   1220 C CB  . VAL A 1 286 ? 132.128 128.644 121.709 1.00 248.56 ?  286  VAL A CB  1 
ATOM   1221 C CG1 . VAL A 1 286 ? 132.332 128.077 120.316 1.00 248.56 ?  286  VAL A CG1 1 
ATOM   1222 C CG2 . VAL A 1 286 ? 133.398 128.455 122.511 1.00 248.56 ?  286  VAL A CG2 1 
ATOM   1223 N N   . LEU A 1 287 ? 129.368 130.011 122.001 1.00 238.93 ?  287  LEU A N   1 
ATOM   1224 C CA  . LEU A 1 287 ? 127.965 130.153 121.633 1.00 238.93 ?  287  LEU A CA  1 
ATOM   1225 C C   . LEU A 1 287 ? 127.663 131.565 121.166 1.00 238.93 ?  287  LEU A C   1 
ATOM   1226 O O   . LEU A 1 287 ? 126.995 131.750 120.153 1.00 238.93 ?  287  LEU A O   1 
ATOM   1227 C CB  . LEU A 1 287 ? 127.093 129.805 122.831 1.00 238.93 ?  287  LEU A CB  1 
ATOM   1228 C CG  . LEU A 1 287 ? 126.461 128.417 122.915 1.00 238.93 ?  287  LEU A CG  1 
ATOM   1229 C CD1 . LEU A 1 287 ? 124.952 128.524 122.769 1.00 238.93 ?  287  LEU A CD1 1 
ATOM   1230 C CD2 . LEU A 1 287 ? 127.036 127.467 121.877 1.00 238.93 ?  287  LEU A CD2 1 
ATOM   1231 N N   . PHE A 1 288 ? 128.152 132.563 121.898 1.00 237.90 ?  288  PHE A N   1 
ATOM   1232 C CA  . PHE A 1 288 ? 127.959 133.956 121.518 1.00 237.90 ?  288  PHE A CA  1 
ATOM   1233 C C   . PHE A 1 288 ? 128.462 134.179 120.120 1.00 237.90 ?  288  PHE A C   1 
ATOM   1234 O O   . PHE A 1 288 ? 127.731 134.683 119.293 1.00 237.90 ?  288  PHE A O   1 
ATOM   1235 C CB  . PHE A 1 288 ? 128.718 134.861 122.477 1.00 237.90 ?  288  PHE A CB  1 
ATOM   1236 C CG  . PHE A 1 288 ? 128.184 136.258 122.559 1.00 237.90 ?  288  PHE A CG  1 
ATOM   1237 C CD1 . PHE A 1 288 ? 126.884 136.495 122.958 1.00 237.90 ?  288  PHE A CD1 1 
ATOM   1238 C CD2 . PHE A 1 288 ? 128.996 137.337 122.259 1.00 237.90 ?  288  PHE A CD2 1 
ATOM   1239 C CE1 . PHE A 1 288 ? 126.400 137.783 123.044 1.00 237.90 ?  288  PHE A CE1 1 
ATOM   1240 C CE2 . PHE A 1 288 ? 128.518 138.628 122.346 1.00 237.90 ?  288  PHE A CE2 1 
ATOM   1241 C CZ  . PHE A 1 288 ? 127.216 138.850 122.737 1.00 237.90 ?  288  PHE A CZ  1 
ATOM   1242 N N   . SER A 1 289 ? 129.701 133.795 119.850 1.00 247.17 ?  289  SER A N   1 
ATOM   1243 C CA  . SER A 1 289 ? 130.275 133.938 118.520 1.00 247.17 ?  289  SER A CA  1 
ATOM   1244 C C   . SER A 1 289 ? 129.384 133.379 117.443 1.00 247.17 ?  289  SER A C   1 
ATOM   1245 O O   . SER A 1 289 ? 129.062 134.074 116.489 1.00 247.17 ?  289  SER A O   1 
ATOM   1246 C CB  . SER A 1 289 ? 131.608 133.210 118.458 1.00 247.17 ?  289  SER A CB  1 
ATOM   1247 O OG  . SER A 1 289 ? 131.951 132.871 117.125 1.00 247.17 ?  289  SER A OG  1 
ATOM   1248 N N   . ILE A 1 290 ? 129.022 132.110 117.566 1.00 266.47 ?  290  ILE A N   1 
ATOM   1249 C CA  . ILE A 1 290 ? 128.161 131.468 116.584 1.00 266.47 ?  290  ILE A CA  1 
ATOM   1250 C C   . ILE A 1 290 ? 126.987 132.358 116.242 1.00 266.47 ?  290  ILE A C   1 
ATOM   1251 O O   . ILE A 1 290 ? 126.664 132.544 115.069 1.00 266.47 ?  290  ILE A O   1 
ATOM   1252 C CB  . ILE A 1 290 ? 127.625 130.143 117.153 1.00 266.47 ?  290  ILE A CB  1 
ATOM   1253 C CG1 . ILE A 1 290 ? 128.717 129.075 117.133 1.00 266.47 ?  290  ILE A CG1 1 
ATOM   1254 C CG2 . ILE A 1 290 ? 126.380 129.676 116.415 1.00 266.47 ?  290  ILE A CG2 1 
ATOM   1255 C CD1 . ILE A 1 290 ? 128.494 127.981 118.149 1.00 266.47 ?  290  ILE A CD1 1 
ATOM   1256 N N   . GLU A 1 291 ? 126.365 132.940 117.257 1.00 258.40 ?  291  GLU A N   1 
ATOM   1257 C CA  . GLU A 1 291 ? 125.176 133.745 117.026 1.00 258.40 ?  291  GLU A CA  1 
ATOM   1258 C C   . GLU A 1 291 ? 125.458 135.150 116.542 1.00 258.40 ?  291  GLU A C   1 
ATOM   1259 O O   . GLU A 1 291 ? 124.871 135.587 115.556 1.00 258.40 ?  291  GLU A O   1 
ATOM   1260 C CB  . GLU A 1 291 ? 124.330 133.789 118.296 1.00 258.40 ?  291  GLU A CB  1 
ATOM   1261 C CG  . GLU A 1 291 ? 123.611 132.484 118.593 1.00 258.40 ?  291  GLU A CG  1 
ATOM   1262 C CD  . GLU A 1 291 ? 123.438 132.233 120.075 1.00 258.40 ?  291  GLU A CD  1 
ATOM   1263 O OE1 . GLU A 1 291 ? 123.949 131.209 120.571 1.00 258.40 ?  291  GLU A OE1 1 
ATOM   1264 O OE2 . GLU A 1 291 ? 122.785 133.055 120.745 1.00 258.40 -1 291  GLU A OE2 1 
ATOM   1265 N N   . VAL A 1 292 ? 126.354 135.866 117.211 1.00 252.65 ?  292  VAL A N   1 
ATOM   1266 C CA  . VAL A 1 292 ? 126.589 137.267 116.853 1.00 252.65 ?  292  VAL A CA  1 
ATOM   1267 C C   . VAL A 1 292 ? 127.140 137.493 115.459 1.00 252.65 ?  292  VAL A C   1 
ATOM   1268 O O   . VAL A 1 292 ? 126.907 138.540 114.880 1.00 252.65 ?  292  VAL A O   1 
ATOM   1269 C CB  . VAL A 1 292 ? 127.472 138.021 117.872 1.00 252.65 ?  292  VAL A CB  1 
ATOM   1270 C CG1 . VAL A 1 292 ? 126.779 138.101 119.215 1.00 252.65 ?  292  VAL A CG1 1 
ATOM   1271 C CG2 . VAL A 1 292 ? 128.856 137.405 117.987 1.00 252.65 ?  292  VAL A CG2 1 
ATOM   1272 N N   . THR A 1 293 ? 127.873 136.531 114.918 1.00 257.68 ?  293  THR A N   1 
ATOM   1273 C CA  . THR A 1 293 ? 128.481 136.740 113.618 1.00 257.68 ?  293  THR A CA  1 
ATOM   1274 C C   . THR A 1 293 ? 127.798 135.938 112.531 1.00 257.68 ?  293  THR A C   1 
ATOM   1275 O O   . THR A 1 293 ? 126.986 136.473 111.784 1.00 257.68 ?  293  THR A O   1 
ATOM   1276 C CB  . THR A 1 293 ? 129.988 136.429 113.631 1.00 257.68 ?  293  THR A CB  1 
ATOM   1277 O OG1 . THR A 1 293 ? 130.244 135.285 114.452 1.00 257.68 ?  293  THR A OG1 1 
ATOM   1278 C CG2 . THR A 1 293 ? 130.768 137.618 114.167 1.00 257.68 ?  293  THR A CG2 1 
ATOM   1279 N N   . SER A 1 294 ? 128.103 134.653 112.448 1.00 249.50 ?  294  SER A N   1 
ATOM   1280 C CA  . SER A 1 294 ? 127.548 133.825 111.386 1.00 249.50 ?  294  SER A CA  1 
ATOM   1281 C C   . SER A 1 294 ? 126.073 133.509 111.538 1.00 249.50 ?  294  SER A C   1 
ATOM   1282 O O   . SER A 1 294 ? 125.465 133.810 112.563 1.00 249.50 ?  294  SER A O   1 
ATOM   1283 C CB  . SER A 1 294 ? 128.335 132.517 111.289 1.00 249.50 ?  294  SER A CB  1 
ATOM   1284 O OG  . SER A 1 294 ? 128.141 131.893 110.031 1.00 249.50 ?  294  SER A OG  1 
ATOM   1285 N N   . THR A 1 295 ? 125.491 132.903 110.511 1.00 214.64 ?  295  THR A N   1 
ATOM   1286 C CA  . THR A 1 295 ? 124.094 132.500 110.576 1.00 214.64 ?  295  THR A CA  1 
ATOM   1287 C C   . THR A 1 295 ? 124.071 130.991 110.417 1.00 214.64 ?  295  THR A C   1 
ATOM   1288 O O   . THR A 1 295 ? 123.182 130.323 110.938 1.00 214.64 ?  295  THR A O   1 
ATOM   1289 C CB  . THR A 1 295 ? 123.268 133.166 109.460 1.00 214.64 ?  295  THR A CB  1 
ATOM   1290 O OG1 . THR A 1 295 ? 122.291 132.242 108.966 1.00 214.64 ?  295  THR A OG1 1 
ATOM   1291 C CG2 . THR A 1 295 ? 124.166 133.610 108.315 1.00 214.64 ?  295  THR A CG2 1 
ATOM   1292 N N   . TYR A 1 296 ? 125.056 130.452 109.704 1.00 214.03 ?  296  TYR A N   1 
ATOM   1293 C CA  . TYR A 1 296 ? 125.150 129.008 109.497 1.00 214.03 ?  296  TYR A CA  1 
ATOM   1294 C C   . TYR A 1 296 ? 126.538 128.554 109.907 1.00 214.03 ?  296  TYR A C   1 
ATOM   1295 O O   . TYR A 1 296 ? 127.422 128.427 109.064 1.00 214.03 ?  296  TYR A O   1 
ATOM   1296 C CB  . TYR A 1 296 ? 124.917 128.659 108.030 1.00 214.03 ?  296  TYR A CB  1 
ATOM   1297 C CG  . TYR A 1 296 ? 123.544 129.027 107.530 1.00 214.03 ?  296  TYR A CG  1 
ATOM   1298 C CD1 . TYR A 1 296 ? 122.418 128.366 107.996 1.00 214.03 ?  296  TYR A CD1 1 
ATOM   1299 C CD2 . TYR A 1 296 ? 123.372 130.038 106.595 1.00 214.03 ?  296  TYR A CD2 1 
ATOM   1300 C CE1 . TYR A 1 296 ? 121.157 128.701 107.546 1.00 214.03 ?  296  TYR A CE1 1 
ATOM   1301 C CE2 . TYR A 1 296 ? 122.115 130.379 106.139 1.00 214.03 ?  296  TYR A CE2 1 
ATOM   1302 C CZ  . TYR A 1 296 ? 121.011 129.707 106.618 1.00 214.03 ?  296  TYR A CZ  1 
ATOM   1303 O OH  . TYR A 1 296 ? 119.754 130.038 106.170 1.00 214.03 ?  296  TYR A OH  1 
ATOM   1304 N N   . PHE A 1 297 ? 126.737 128.308 111.195 1.00 202.07 ?  297  PHE A N   1 
ATOM   1305 C CA  . PHE A 1 297 ? 128.050 127.918 111.690 1.00 202.07 ?  297  PHE A CA  1 
ATOM   1306 C C   . PHE A 1 297 ? 128.418 126.492 111.339 1.00 202.07 ?  297  PHE A C   1 
ATOM   1307 O O   . PHE A 1 297 ? 127.553 125.680 111.019 1.00 202.07 ?  297  PHE A O   1 
ATOM   1308 C CB  . PHE A 1 297 ? 128.144 128.120 113.205 1.00 202.07 ?  297  PHE A CB  1 
ATOM   1309 C CG  . PHE A 1 297 ? 127.482 127.034 114.013 1.00 202.07 ?  297  PHE A CG  1 
ATOM   1310 C CD1 . PHE A 1 297 ? 126.104 126.987 114.143 1.00 202.07 ?  297  PHE A CD1 1 
ATOM   1311 C CD2 . PHE A 1 297 ? 128.242 126.074 114.664 1.00 202.07 ?  297  PHE A CD2 1 
ATOM   1312 C CE1 . PHE A 1 297 ? 125.497 125.996 114.891 1.00 202.07 ?  297  PHE A CE1 1 
ATOM   1313 C CE2 . PHE A 1 297 ? 127.641 125.080 115.410 1.00 202.07 ?  297  PHE A CE2 1 
ATOM   1314 C CZ  . PHE A 1 297 ? 126.267 125.042 115.525 1.00 202.07 ?  297  PHE A CZ  1 
ATOM   1315 N N   . ALA A 1 298 ? 129.704 126.181 111.402 1.00 189.57 ?  298  ALA A N   1 
ATOM   1316 C CA  . ALA A 1 298 ? 130.148 124.826 111.139 1.00 189.57 ?  298  ALA A CA  1 
ATOM   1317 C C   . ALA A 1 298 ? 130.522 124.218 112.469 1.00 189.57 ?  298  ALA A C   1 
ATOM   1318 O O   . ALA A 1 298 ? 131.058 124.903 113.334 1.00 189.57 ?  298  ALA A O   1 
ATOM   1319 C CB  . ALA A 1 298 ? 131.337 124.839 110.207 1.00 189.57 ?  298  ALA A CB  1 
ATOM   1320 N N   . VAL A 1 299 ? 130.232 122.937 112.655 1.00 207.10 ?  299  VAL A N   1 
ATOM   1321 C CA  . VAL A 1 299 ? 130.509 122.301 113.939 1.00 207.10 ?  299  VAL A CA  1 
ATOM   1322 C C   . VAL A 1 299 ? 132.007 122.170 114.156 1.00 207.10 ?  299  VAL A C   1 
ATOM   1323 O O   . VAL A 1 299 ? 132.455 122.063 115.292 1.00 207.10 ?  299  VAL A O   1 
ATOM   1324 C CB  . VAL A 1 299 ? 129.828 120.931 114.077 1.00 207.10 ?  299  VAL A CB  1 
ATOM   1325 C CG1 . VAL A 1 299 ? 129.158 120.813 115.437 1.00 207.10 ?  299  VAL A CG1 1 
ATOM   1326 C CG2 . VAL A 1 299 ? 128.818 120.732 112.961 1.00 207.10 ?  299  VAL A CG2 1 
ATOM   1327 N N   . ARG A 1 300 ? 132.786 122.179 113.077 1.00 246.42 ?  300  ARG A N   1 
ATOM   1328 C CA  . ARG A 1 300 ? 134.230 122.142 113.235 1.00 246.42 ?  300  ARG A CA  1 
ATOM   1329 C C   . ARG A 1 300 ? 134.653 123.411 113.946 1.00 246.42 ?  300  ARG A C   1 
ATOM   1330 O O   . ARG A 1 300 ? 135.398 123.342 114.900 1.00 246.42 ?  300  ARG A O   1 
ATOM   1331 C CB  . ARG A 1 300 ? 134.959 121.977 111.903 1.00 246.42 ?  300  ARG A CB  1 
ATOM   1332 C CG  . ARG A 1 300 ? 134.382 122.754 110.733 1.00 246.42 ?  300  ARG A CG  1 
ATOM   1333 C CD  . ARG A 1 300 ? 135.435 123.665 110.124 1.00 246.42 ?  300  ARG A CD  1 
ATOM   1334 N NE  . ARG A 1 300 ? 136.774 123.103 110.274 1.00 246.42 ?  300  ARG A NE  1 
ATOM   1335 C CZ  . ARG A 1 300 ? 137.881 123.823 110.425 1.00 246.42 ?  300  ARG A CZ  1 
ATOM   1336 N NH1 . ARG A 1 300 ? 139.052 123.218 110.554 1.00 246.42 1  300  ARG A NH1 1 
ATOM   1337 N NH2 . ARG A 1 300 ? 137.819 125.144 110.449 1.00 246.42 ?  300  ARG A NH2 1 
ATOM   1338 N N   . ASN A 1 301 ? 134.150 124.561 113.507 1.00 242.46 ?  301  ASN A N   1 
ATOM   1339 C CA  . ASN A 1 301 ? 134.496 125.832 114.125 1.00 242.46 ?  301  ASN A CA  1 
ATOM   1340 C C   . ASN A 1 301 ? 133.940 125.933 115.531 1.00 242.46 ?  301  ASN A C   1 
ATOM   1341 O O   . ASN A 1 301 ? 134.466 126.676 116.353 1.00 242.46 ?  301  ASN A O   1 
ATOM   1342 C CB  . ASN A 1 301 ? 133.996 126.994 113.277 1.00 242.46 ?  301  ASN A CB  1 
ATOM   1343 C CG  . ASN A 1 301 ? 134.756 127.134 111.979 1.00 242.46 ?  301  ASN A CG  1 
ATOM   1344 O OD1 . ASN A 1 301 ? 135.934 126.792 111.897 1.00 242.46 ?  301  ASN A OD1 1 
ATOM   1345 N ND2 . ASN A 1 301 ? 134.084 127.640 110.955 1.00 242.46 ?  301  ASN A ND2 1 
ATOM   1346 N N   . TYR A 1 302 ? 132.876 125.198 115.817 1.00 189.18 ?  302  TYR A N   1 
ATOM   1347 C CA  . TYR A 1 302 ? 132.330 125.186 117.165 1.00 189.18 ?  302  TYR A CA  1 
ATOM   1348 C C   . TYR A 1 302 ? 133.312 124.481 118.078 1.00 189.18 ?  302  TYR A C   1 
ATOM   1349 O O   . TYR A 1 302 ? 133.583 124.948 119.179 1.00 189.18 ?  302  TYR A O   1 
ATOM   1350 C CB  . TYR A 1 302 ? 130.979 124.476 117.185 1.00 189.18 ?  302  TYR A CB  1 
ATOM   1351 C CG  . TYR A 1 302 ? 130.466 124.147 118.565 1.00 189.18 ?  302  TYR A CG  1 
ATOM   1352 C CD1 . TYR A 1 302 ? 130.139 125.153 119.464 1.00 189.18 ?  302  TYR A CD1 1 
ATOM   1353 C CD2 . TYR A 1 302 ? 130.300 122.830 118.968 1.00 189.18 ?  302  TYR A CD2 1 
ATOM   1354 C CE1 . TYR A 1 302 ? 129.671 124.856 120.728 1.00 189.18 ?  302  TYR A CE1 1 
ATOM   1355 C CE2 . TYR A 1 302 ? 129.829 122.525 120.228 1.00 189.18 ?  302  TYR A CE2 1 
ATOM   1356 C CZ  . TYR A 1 302 ? 129.517 123.540 121.104 1.00 189.18 ?  302  TYR A CZ  1 
ATOM   1357 O OH  . TYR A 1 302 ? 129.047 123.236 122.360 1.00 189.18 ?  302  TYR A OH  1 
ATOM   1358 N N   . TRP A 1 303 ? 133.877 123.376 117.601 1.00 253.38 ?  303  TRP A N   1 
ATOM   1359 C CA  . TRP A 1 303 ? 134.839 122.611 118.389 1.00 253.38 ?  303  TRP A CA  1 
ATOM   1360 C C   . TRP A 1 303 ? 136.197 123.274 118.407 1.00 253.38 ?  303  TRP A C   1 
ATOM   1361 O O   . TRP A 1 303 ? 136.917 123.173 119.392 1.00 253.38 ?  303  TRP A O   1 
ATOM   1362 C CB  . TRP A 1 303 ? 134.997 121.215 117.808 1.00 253.38 ?  303  TRP A CB  1 
ATOM   1363 C CG  . TRP A 1 303 ? 133.796 120.370 117.966 1.00 253.38 ?  303  TRP A CG  1 
ATOM   1364 C CD1 . TRP A 1 303 ? 132.924 120.371 119.010 1.00 253.38 ?  303  TRP A CD1 1 
ATOM   1365 C CD2 . TRP A 1 303 ? 133.326 119.381 117.048 1.00 253.38 ?  303  TRP A CD2 1 
ATOM   1366 N NE1 . TRP A 1 303 ? 131.933 119.446 118.799 1.00 253.38 ?  303  TRP A NE1 1 
ATOM   1367 C CE2 . TRP A 1 303 ? 132.159 118.824 117.599 1.00 253.38 ?  303  TRP A CE2 1 
ATOM   1368 C CE3 . TRP A 1 303 ? 133.778 118.915 115.812 1.00 253.38 ?  303  TRP A CE3 1 
ATOM   1369 C CZ2 . TRP A 1 303 ? 131.438 117.823 116.959 1.00 253.38 ?  303  TRP A CZ2 1 
ATOM   1370 C CZ3 . TRP A 1 303 ? 133.061 117.924 115.177 1.00 253.38 ?  303  TRP A CZ3 1 
ATOM   1371 C CH2 . TRP A 1 303 ? 131.904 117.388 115.751 1.00 253.38 ?  303  TRP A CH2 1 
ATOM   1372 N N   . ARG A 1 304 ? 136.563 123.927 117.312 1.00 260.72 ?  304  ARG A N   1 
ATOM   1373 C CA  . ARG A 1 304 ? 137.840 124.621 117.252 1.00 260.72 ?  304  ARG A CA  1 
ATOM   1374 C C   . ARG A 1 304 ? 137.791 125.768 118.234 1.00 260.72 ?  304  ARG A C   1 
ATOM   1375 O O   . ARG A 1 304 ? 138.725 125.971 119.002 1.00 260.72 ?  304  ARG A O   1 
ATOM   1376 C CB  . ARG A 1 304 ? 138.102 125.138 115.844 1.00 260.72 ?  304  ARG A CB  1 
ATOM   1377 C CG  . ARG A 1 304 ? 138.595 124.084 114.870 1.00 260.72 ?  304  ARG A CG  1 
ATOM   1378 C CD  . ARG A 1 304 ? 139.644 124.626 113.913 1.00 260.72 ?  304  ARG A CD  1 
ATOM   1379 N NE  . ARG A 1 304 ? 139.355 125.973 113.436 1.00 260.72 ?  304  ARG A NE  1 
ATOM   1380 C CZ  . ARG A 1 304 ? 140.291 126.837 113.050 1.00 260.72 ?  304  ARG A CZ  1 
ATOM   1381 N NH1 . ARG A 1 304 ? 141.568 126.486 113.093 1.00 260.72 1  304  ARG A NH1 1 
ATOM   1382 N NH2 . ARG A 1 304 ? 139.954 128.045 112.622 1.00 260.72 ?  304  ARG A NH2 1 
ATOM   1383 N N   . GLY A 1 305 ? 136.685 126.502 118.239 1.00 246.55 ?  305  GLY A N   1 
ATOM   1384 C CA  . GLY A 1 305 ? 136.522 127.603 119.167 1.00 246.55 ?  305  GLY A CA  1 
ATOM   1385 C C   . GLY A 1 305 ? 136.446 127.120 120.588 1.00 246.55 ?  305  GLY A C   1 
ATOM   1386 O O   . GLY A 1 305 ? 136.958 127.770 121.478 1.00 246.55 ?  305  GLY A O   1 
ATOM   1387 N N   . PHE A 1 306 ? 135.813 125.978 120.805 1.00 235.42 ?  306  PHE A N   1 
ATOM   1388 C CA  . PHE A 1 306 ? 135.723 125.401 122.135 1.00 235.42 ?  306  PHE A CA  1 
ATOM   1389 C C   . PHE A 1 306 ? 137.097 125.121 122.688 1.00 235.42 ?  306  PHE A C   1 
ATOM   1390 O O   . PHE A 1 306 ? 137.414 125.534 123.794 1.00 235.42 ?  306  PHE A O   1 
ATOM   1391 C CB  . PHE A 1 306 ? 134.952 124.092 122.073 1.00 235.42 ?  306  PHE A CB  1 
ATOM   1392 C CG  . PHE A 1 306 ? 133.957 123.925 123.165 1.00 235.42 ?  306  PHE A CG  1 
ATOM   1393 C CD1 . PHE A 1 306 ? 132.724 124.537 123.087 1.00 235.42 ?  306  PHE A CD1 1 
ATOM   1394 C CD2 . PHE A 1 306 ? 134.253 123.148 124.269 1.00 235.42 ?  306  PHE A CD2 1 
ATOM   1395 C CE1 . PHE A 1 306 ? 131.799 124.381 124.095 1.00 235.42 ?  306  PHE A CE1 1 
ATOM   1396 C CE2 . PHE A 1 306 ? 133.335 122.986 125.282 1.00 235.42 ?  306  PHE A CE2 1 
ATOM   1397 C CZ  . PHE A 1 306 ? 132.105 123.603 125.194 1.00 235.42 ?  306  PHE A CZ  1 
ATOM   1398 N N   . PHE A 1 307 ? 137.914 124.413 121.919 1.00 255.37 ?  307  PHE A N   1 
ATOM   1399 C CA  . PHE A 1 307 ? 139.249 124.069 122.371 1.00 255.37 ?  307  PHE A CA  1 
ATOM   1400 C C   . PHE A 1 307 ? 140.054 125.316 122.674 1.00 255.37 ?  307  PHE A C   1 
ATOM   1401 O O   . PHE A 1 307 ? 140.701 125.411 123.716 1.00 255.37 ?  307  PHE A O   1 
ATOM   1402 C CB  . PHE A 1 307 ? 139.965 123.226 121.316 1.00 255.37 ?  307  PHE A CB  1 
ATOM   1403 C CG  . PHE A 1 307 ? 141.394 122.916 121.657 1.00 255.37 ?  307  PHE A CG  1 
ATOM   1404 C CD1 . PHE A 1 307 ? 141.701 122.100 122.729 1.00 255.37 ?  307  PHE A CD1 1 
ATOM   1405 C CD2 . PHE A 1 307 ? 142.427 123.445 120.908 1.00 255.37 ?  307  PHE A CD2 1 
ATOM   1406 C CE1 . PHE A 1 307 ? 143.015 121.819 123.047 1.00 255.37 ?  307  PHE A CE1 1 
ATOM   1407 C CE2 . PHE A 1 307 ? 143.740 123.170 121.218 1.00 255.37 ?  307  PHE A CE2 1 
ATOM   1408 C CZ  . PHE A 1 307 ? 144.035 122.355 122.289 1.00 255.37 ?  307  PHE A CZ  1 
ATOM   1409 N N   . ALA A 1 308 ? 140.015 126.282 121.770 1.00 251.09 ?  308  ALA A N   1 
ATOM   1410 C CA  . ALA A 1 308 ? 140.805 127.482 121.955 1.00 251.09 ?  308  ALA A CA  1 
ATOM   1411 C C   . ALA A 1 308 ? 140.344 128.313 123.143 1.00 251.09 ?  308  ALA A C   1 
ATOM   1412 O O   . ALA A 1 308 ? 141.162 128.905 123.835 1.00 251.09 ?  308  ALA A O   1 
ATOM   1413 C CB  . ALA A 1 308 ? 140.805 128.294 120.684 1.00 251.09 ?  308  ALA A CB  1 
ATOM   1414 N N   . ALA A 1 309 ? 139.040 128.343 123.400 1.00 248.92 ?  309  ALA A N   1 
ATOM   1415 C CA  . ALA A 1 309 ? 138.509 129.102 124.523 1.00 248.92 ?  309  ALA A CA  1 
ATOM   1416 C C   . ALA A 1 309 ? 138.795 128.440 125.859 1.00 248.92 ?  309  ALA A C   1 
ATOM   1417 O O   . ALA A 1 309 ? 138.941 129.117 126.869 1.00 248.92 ?  309  ALA A O   1 
ATOM   1418 C CB  . ALA A 1 309 ? 137.020 129.323 124.359 1.00 248.92 ?  309  ALA A CB  1 
ATOM   1419 N N   . THR A 1 310 ? 138.876 127.117 125.875 1.00 278.73 ?  310  THR A N   1 
ATOM   1420 C CA  . THR A 1 310 ? 139.204 126.425 127.110 1.00 278.73 ?  310  THR A CA  1 
ATOM   1421 C C   . THR A 1 310 ? 140.680 126.562 127.389 1.00 278.73 ?  310  THR A C   1 
ATOM   1422 O O   . THR A 1 310 ? 141.094 126.542 128.542 1.00 278.73 ?  310  THR A O   1 
ATOM   1423 C CB  . THR A 1 310 ? 138.793 124.944 127.089 1.00 278.73 ?  310  THR A CB  1 
ATOM   1424 O OG1 . THR A 1 310 ? 139.312 124.313 125.916 1.00 278.73 ?  310  THR A OG1 1 
ATOM   1425 C CG2 . THR A 1 310 ? 137.280 124.813 127.105 1.00 278.73 ?  310  THR A CG2 1 
ATOM   1426 N N   . PHE A 1 311 ? 141.487 126.717 126.345 1.00 245.67 ?  311  PHE A N   1 
ATOM   1427 C CA  . PHE A 1 311 ? 142.903 126.958 126.569 1.00 245.67 ?  311  PHE A CA  1 
ATOM   1428 C C   . PHE A 1 311 ? 143.048 128.340 127.159 1.00 245.67 ?  311  PHE A C   1 
ATOM   1429 O O   . PHE A 1 311 ? 143.819 128.534 128.087 1.00 245.67 ?  311  PHE A O   1 
ATOM   1430 C CB  . PHE A 1 311 ? 143.712 126.844 125.284 1.00 245.67 ?  311  PHE A CB  1 
ATOM   1431 C CG  . PHE A 1 311 ? 145.168 126.614 125.524 1.00 245.67 ?  311  PHE A CG  1 
ATOM   1432 C CD1 . PHE A 1 311 ? 145.624 125.369 125.908 1.00 245.67 ?  311  PHE A CD1 1 
ATOM   1433 C CD2 . PHE A 1 311 ? 146.075 127.646 125.400 1.00 245.67 ?  311  PHE A CD2 1 
ATOM   1434 C CE1 . PHE A 1 311 ? 146.964 125.151 126.144 1.00 245.67 ?  311  PHE A CE1 1 
ATOM   1435 C CE2 . PHE A 1 311 ? 147.417 127.438 125.637 1.00 245.67 ?  311  PHE A CE2 1 
ATOM   1436 C CZ  . PHE A 1 311 ? 147.864 126.188 126.010 1.00 245.67 ?  311  PHE A CZ  1 
ATOM   1437 N N   . SER A 1 312 ? 142.292 129.300 126.641 1.00 245.26 ?  312  SER A N   1 
ATOM   1438 C CA  . SER A 1 312 ? 142.314 130.645 127.188 1.00 245.26 ?  312  SER A CA  1 
ATOM   1439 C C   . SER A 1 312 ? 141.965 130.618 128.662 1.00 245.26 ?  312  SER A C   1 
ATOM   1440 O O   . SER A 1 312 ? 142.632 131.250 129.467 1.00 245.26 ?  312  SER A O   1 
ATOM   1441 C CB  . SER A 1 312 ? 141.316 131.521 126.438 1.00 245.26 ?  312  SER A CB  1 
ATOM   1442 O OG  . SER A 1 312 ? 141.937 132.674 125.906 1.00 245.26 ?  312  SER A OG  1 
ATOM   1443 N N   . ALA A 1 313 ? 140.927 129.873 129.024 1.00 226.87 ?  313  ALA A N   1 
ATOM   1444 C CA  . ALA A 1 313 ? 140.513 129.771 130.416 1.00 226.87 ?  313  ALA A CA  1 
ATOM   1445 C C   . ALA A 1 313 ? 141.569 129.151 131.307 1.00 226.87 ?  313  ALA A C   1 
ATOM   1446 O O   . ALA A 1 313 ? 141.734 129.561 132.449 1.00 226.87 ?  313  ALA A O   1 
ATOM   1447 C CB  . ALA A 1 313 ? 139.228 128.977 130.508 1.00 226.87 ?  313  ALA A CB  1 
ATOM   1448 N N   . PHE A 1 314 ? 142.279 128.157 130.798 1.00 245.76 ?  314  PHE A N   1 
ATOM   1449 C CA  . PHE A 1 314 ? 143.330 127.514 131.573 1.00 245.76 ?  314  PHE A CA  1 
ATOM   1450 C C   . PHE A 1 314 ? 144.476 128.489 131.816 1.00 245.76 ?  314  PHE A C   1 
ATOM   1451 O O   . PHE A 1 314 ? 144.991 128.577 132.928 1.00 245.76 ?  314  PHE A O   1 
ATOM   1452 C CB  . PHE A 1 314 ? 143.778 126.215 130.876 1.00 245.76 ?  314  PHE A CB  1 
ATOM   1453 C CG  . PHE A 1 314 ? 145.253 125.933 130.956 1.00 245.76 ?  314  PHE A CG  1 
ATOM   1454 C CD1 . PHE A 1 314 ? 145.811 125.388 132.102 1.00 245.76 ?  314  PHE A CD1 1 
ATOM   1455 C CD2 . PHE A 1 314 ? 146.074 126.169 129.866 1.00 245.76 ?  314  PHE A CD2 1 
ATOM   1456 C CE1 . PHE A 1 314 ? 147.163 125.125 132.171 1.00 245.76 ?  314  PHE A CE1 1 
ATOM   1457 C CE2 . PHE A 1 314 ? 147.427 125.911 129.930 1.00 245.76 ?  314  PHE A CE2 1 
ATOM   1458 C CZ  . PHE A 1 314 ? 147.972 125.384 131.082 1.00 245.76 ?  314  PHE A CZ  1 
ATOM   1459 N N   . VAL A 1 315 ? 144.862 129.239 130.788 1.00 246.86 ?  315  VAL A N   1 
ATOM   1460 C CA  . VAL A 1 315 ? 145.941 130.198 130.938 1.00 246.86 ?  315  VAL A CA  1 
ATOM   1461 C C   . VAL A 1 315 ? 145.499 131.258 131.929 1.00 246.86 ?  315  VAL A C   1 
ATOM   1462 O O   . VAL A 1 315 ? 146.258 131.650 132.801 1.00 246.86 ?  315  VAL A O   1 
ATOM   1463 C CB  . VAL A 1 315 ? 146.360 130.810 129.585 1.00 246.86 ?  315  VAL A CB  1 
ATOM   1464 C CG1 . VAL A 1 315 ? 147.485 131.818 129.759 1.00 246.86 ?  315  VAL A CG1 1 
ATOM   1465 C CG2 . VAL A 1 315 ? 146.817 129.720 128.638 1.00 246.86 ?  315  VAL A CG2 1 
ATOM   1466 N N   . PHE A 1 316 ? 144.247 131.684 131.831 1.00 202.01 ?  316  PHE A N   1 
ATOM   1467 C CA  . PHE A 1 316 ? 143.705 132.670 132.764 1.00 202.01 ?  316  PHE A CA  1 
ATOM   1468 C C   . PHE A 1 316 ? 143.811 132.197 134.199 1.00 202.01 ?  316  PHE A C   1 
ATOM   1469 O O   . PHE A 1 316 ? 144.127 132.984 135.082 1.00 202.01 ?  316  PHE A O   1 
ATOM   1470 C CB  . PHE A 1 316 ? 142.244 132.907 132.445 1.00 202.01 ?  316  PHE A CB  1 
ATOM   1471 C CG  . PHE A 1 316 ? 141.935 134.307 132.053 1.00 202.01 ?  316  PHE A CG  1 
ATOM   1472 C CD1 . PHE A 1 316 ? 142.945 135.193 131.757 1.00 202.01 ?  316  PHE A CD1 1 
ATOM   1473 C CD2 . PHE A 1 316 ? 140.628 134.738 131.984 1.00 202.01 ?  316  PHE A CD2 1 
ATOM   1474 C CE1 . PHE A 1 316 ? 142.654 136.487 131.396 1.00 202.01 ?  316  PHE A CE1 1 
ATOM   1475 C CE2 . PHE A 1 316 ? 140.333 136.034 131.631 1.00 202.01 ?  316  PHE A CE2 1 
ATOM   1476 C CZ  . PHE A 1 316 ? 141.350 136.912 131.339 1.00 202.01 ?  316  PHE A CZ  1 
ATOM   1477 N N   . ARG A 1 317 ? 143.541 130.921 134.439 1.00 206.32 ?  317  ARG A N   1 
ATOM   1478 C CA  . ARG A 1 317 ? 143.587 130.364 135.784 1.00 206.32 ?  317  ARG A CA  1 
ATOM   1479 C C   . ARG A 1 317 ? 144.992 130.360 136.349 1.00 206.32 ?  317  ARG A C   1 
ATOM   1480 O O   . ARG A 1 317 ? 145.182 130.709 137.504 1.00 206.32 ?  317  ARG A O   1 
ATOM   1481 C CB  . ARG A 1 317 ? 143.028 128.945 135.788 1.00 206.32 ?  317  ARG A CB  1 
ATOM   1482 C CG  . ARG A 1 317 ? 141.716 128.805 136.537 1.00 206.32 ?  317  ARG A CG  1 
ATOM   1483 C CD  . ARG A 1 317 ? 140.542 128.677 135.581 1.00 206.32 ?  317  ARG A CD  1 
ATOM   1484 N NE  . ARG A 1 317 ? 140.203 129.952 134.958 1.00 206.32 ?  317  ARG A NE  1 
ATOM   1485 C CZ  . ARG A 1 317 ? 138.983 130.289 134.556 1.00 206.32 ?  317  ARG A CZ  1 
ATOM   1486 N NH1 . ARG A 1 317 ? 138.770 131.472 133.999 1.00 206.32 1  317  ARG A NH1 1 
ATOM   1487 N NH2 . ARG A 1 317 ? 137.975 129.441 134.710 1.00 206.32 ?  317  ARG A NH2 1 
ATOM   1488 N N   . VAL A 1 318 ? 145.975 129.964 135.547 1.00 221.29 ?  318  VAL A N   1 
ATOM   1489 C CA  . VAL A 1 318 ? 147.358 129.996 136.013 1.00 221.29 ?  318  VAL A CA  1 
ATOM   1490 C C   . VAL A 1 318 ? 147.895 131.417 136.181 1.00 221.29 ?  318  VAL A C   1 
ATOM   1491 O O   . VAL A 1 318 ? 148.757 131.647 137.017 1.00 221.29 ?  318  VAL A O   1 
ATOM   1492 C CB  . VAL A 1 318 ? 148.302 129.085 135.191 1.00 221.29 ?  318  VAL A CB  1 
ATOM   1493 C CG1 . VAL A 1 318 ? 147.695 127.703 135.044 1.00 221.29 ?  318  VAL A CG1 1 
ATOM   1494 C CG2 . VAL A 1 318 ? 148.637 129.674 133.834 1.00 221.29 ?  318  VAL A CG2 1 
ATOM   1495 N N   . LEU A 1 319 ? 147.360 132.379 135.434 1.00 214.33 ?  319  LEU A N   1 
ATOM   1496 C CA  . LEU A 1 319 ? 147.774 133.765 135.598 1.00 214.33 ?  319  LEU A CA  1 
ATOM   1497 C C   . LEU A 1 319 ? 147.196 134.262 136.898 1.00 214.33 ?  319  LEU A C   1 
ATOM   1498 O O   . LEU A 1 319 ? 147.836 135.023 137.621 1.00 214.33 ?  319  LEU A O   1 
ATOM   1499 C CB  . LEU A 1 319 ? 147.260 134.611 134.446 1.00 214.33 ?  319  LEU A CB  1 
ATOM   1500 C CG  . LEU A 1 319 ? 148.091 134.635 133.170 1.00 214.33 ?  319  LEU A CG  1 
ATOM   1501 C CD1 . LEU A 1 319 ? 147.198 134.938 131.978 1.00 214.33 ?  319  LEU A CD1 1 
ATOM   1502 C CD2 . LEU A 1 319 ? 149.194 135.671 133.293 1.00 214.33 ?  319  LEU A CD2 1 
ATOM   1503 N N   . ALA A 1 320 ? 145.978 133.830 137.205 1.00 212.63 ?  320  ALA A N   1 
ATOM   1504 C CA  . ALA A 1 320 ? 145.330 134.229 138.448 1.00 212.63 ?  320  ALA A CA  1 
ATOM   1505 C C   . ALA A 1 320 ? 145.890 133.437 139.607 1.00 212.63 ?  320  ALA A C   1 
ATOM   1506 O O   . ALA A 1 320 ? 145.362 133.494 140.711 1.00 212.63 ?  320  ALA A O   1 
ATOM   1507 C CB  . ALA A 1 320 ? 143.831 134.030 138.350 1.00 212.63 ?  320  ALA A CB  1 
ATOM   1508 N N   . VAL A 1 321 ? 146.949 132.682 139.361 1.00 232.14 ?  321  VAL A N   1 
ATOM   1509 C CA  . VAL A 1 321 ? 147.589 131.935 140.429 1.00 232.14 ?  321  VAL A CA  1 
ATOM   1510 C C   . VAL A 1 321 ? 148.928 132.605 140.642 1.00 232.14 ?  321  VAL A C   1 
ATOM   1511 O O   . VAL A 1 321 ? 149.351 132.828 141.778 1.00 232.14 ?  321  VAL A O   1 
ATOM   1512 C CB  . VAL A 1 321 ? 147.742 130.441 140.059 1.00 232.14 ?  321  VAL A CB  1 
ATOM   1513 C CG1 . VAL A 1 321 ? 148.983 129.812 140.676 1.00 232.14 ?  321  VAL A CG1 1 
ATOM   1514 C CG2 . VAL A 1 321 ? 146.500 129.666 140.464 1.00 232.14 ?  321  VAL A CG2 1 
ATOM   1515 N N   . TRP A 1 322 ? 149.574 132.989 139.547 1.00 263.41 ?  322  TRP A N   1 
ATOM   1516 C CA  . TRP A 1 322 ? 150.881 133.623 139.640 1.00 263.41 ?  322  TRP A CA  1 
ATOM   1517 C C   . TRP A 1 322 ? 150.784 134.949 140.357 1.00 263.41 ?  322  TRP A C   1 
ATOM   1518 O O   . TRP A 1 322 ? 151.630 135.279 141.183 1.00 263.41 ?  322  TRP A O   1 
ATOM   1519 C CB  . TRP A 1 322 ? 151.466 133.835 138.250 1.00 263.41 ?  322  TRP A CB  1 
ATOM   1520 C CG  . TRP A 1 322 ? 151.792 132.564 137.552 1.00 263.41 ?  322  TRP A CG  1 
ATOM   1521 C CD1 . TRP A 1 322 ? 152.112 131.370 138.128 1.00 263.41 ?  322  TRP A CD1 1 
ATOM   1522 C CD2 . TRP A 1 322 ? 151.825 132.350 136.138 1.00 263.41 ?  322  TRP A CD2 1 
ATOM   1523 N NE1 . TRP A 1 322 ? 152.343 130.426 137.160 1.00 263.41 ?  322  TRP A NE1 1 
ATOM   1524 C CE2 . TRP A 1 322 ? 152.172 131.003 135.930 1.00 263.41 ?  322  TRP A CE2 1 
ATOM   1525 C CE3 . TRP A 1 322 ? 151.593 133.168 135.030 1.00 263.41 ?  322  TRP A CE3 1 
ATOM   1526 C CZ2 . TRP A 1 322 ? 152.299 130.455 134.657 1.00 263.41 ?  322  TRP A CZ2 1 
ATOM   1527 C CZ3 . TRP A 1 322 ? 151.715 132.623 133.768 1.00 263.41 ?  322  TRP A CZ3 1 
ATOM   1528 C CH2 . TRP A 1 322 ? 152.066 131.281 133.591 1.00 263.41 ?  322  TRP A CH2 1 
ATOM   1529 N N   . ASN A 1 323 ? 149.742 135.718 140.047 1.00 237.10 ?  323  ASN A N   1 
ATOM   1530 C CA  . ASN A 1 323 ? 149.556 137.029 140.662 1.00 237.10 ?  323  ASN A CA  1 
ATOM   1531 C C   . ASN A 1 323 ? 148.453 136.969 141.688 1.00 237.10 ?  323  ASN A C   1 
ATOM   1532 O O   . ASN A 1 323 ? 147.878 138.003 142.028 1.00 237.10 ?  323  ASN A O   1 
ATOM   1533 C CB  . ASN A 1 323 ? 149.185 138.057 139.598 1.00 237.10 ?  323  ASN A CB  1 
ATOM   1534 C CG  . ASN A 1 323 ? 149.996 139.332 139.706 1.00 237.10 ?  323  ASN A CG  1 
ATOM   1535 O OD1 . ASN A 1 323 ? 150.850 139.610 138.867 1.00 237.10 ?  323  ASN A OD1 1 
ATOM   1536 N ND2 . ASN A 1 323 ? 149.728 140.118 140.741 1.00 237.10 ?  323  ASN A ND2 1 
ATOM   1537 N N   . LYS A 1 324 ? 148.150 135.773 142.179 1.00 232.23 ?  324  LYS A N   1 
ATOM   1538 C CA  . LYS A 1 324 ? 147.064 135.587 143.151 1.00 232.23 ?  324  LYS A CA  1 
ATOM   1539 C C   . LYS A 1 324 ? 145.816 136.381 142.820 1.00 232.23 ?  324  LYS A C   1 
ATOM   1540 O O   . LYS A 1 324 ? 145.326 137.138 143.659 1.00 232.23 ?  324  LYS A O   1 
ATOM   1541 C CB  . LYS A 1 324 ? 147.529 135.848 144.586 1.00 232.23 ?  324  LYS A CB  1 
ATOM   1542 C CG  . LYS A 1 324 ? 147.327 134.655 145.509 1.00 232.23 ?  324  LYS A CG  1 
ATOM   1543 C CD  . LYS A 1 324 ? 147.557 133.339 144.778 1.00 232.23 ?  324  LYS A CD  1 
ATOM   1544 C CE  . LYS A 1 324 ? 146.378 132.388 144.930 1.00 232.23 ?  324  LYS A CE  1 
ATOM   1545 N NZ  . LYS A 1 324 ? 145.647 132.210 143.644 1.00 232.23 1  324  LYS A NZ  1 
ATOM   1546 N N   . ASP A 1 325 ? 145.309 136.208 141.604 1.00 221.52 ?  325  ASP A N   1 
ATOM   1547 C CA  . ASP A 1 325 ? 144.111 136.915 141.159 1.00 221.52 ?  325  ASP A CA  1 
ATOM   1548 C C   . ASP A 1 325 ? 144.080 138.395 141.461 1.00 221.52 ?  325  ASP A C   1 
ATOM   1549 O O   . ASP A 1 325 ? 144.934 139.125 140.950 1.00 221.52 ?  325  ASP A O   1 
ATOM   1550 C CB  . ASP A 1 325 ? 142.842 136.238 141.679 1.00 221.52 ?  325  ASP A CB  1 
ATOM   1551 C CG  . ASP A 1 325 ? 141.844 135.969 140.578 1.00 221.52 ?  325  ASP A CG  1 
ATOM   1552 O OD1 . ASP A 1 325 ? 141.763 136.786 139.634 1.00 221.52 ?  325  ASP A OD1 1 
ATOM   1553 O OD2 . ASP A 1 325 ? 141.147 134.935 140.648 1.00 221.52 -1 325  ASP A OD2 1 
ATOM   1554 N N   . ALA A 1 326 ? 143.094 138.840 142.244 1.00 234.28 ?  326  ALA A N   1 
ATOM   1555 C CA  . ALA A 1 326 ? 142.911 140.268 142.570 1.00 234.28 ?  326  ALA A CA  1 
ATOM   1556 C C   . ALA A 1 326 ? 142.514 141.138 141.377 1.00 234.28 ?  326  ALA A C   1 
ATOM   1557 O O   . ALA A 1 326 ? 142.394 142.355 141.515 1.00 234.28 ?  326  ALA A O   1 
ATOM   1558 C CB  . ALA A 1 326 ? 144.097 140.859 143.341 1.00 234.28 ?  326  ALA A CB  1 
ATOM   1559 N N   . VAL A 1 327 ? 142.290 140.523 140.216 1.00 229.27 ?  327  VAL A N   1 
ATOM   1560 C CA  . VAL A 1 327 ? 141.869 141.264 139.031 1.00 229.27 ?  327  VAL A CA  1 
ATOM   1561 C C   . VAL A 1 327 ? 140.754 140.519 138.330 1.00 229.27 ?  327  VAL A C   1 
ATOM   1562 O O   . VAL A 1 327 ? 139.954 139.865 139.000 1.00 229.27 ?  327  VAL A O   1 
ATOM   1563 C CB  . VAL A 1 327 ? 143.023 141.491 138.029 1.00 229.27 ?  327  VAL A CB  1 
ATOM   1564 C CG1 . VAL A 1 327 ? 143.768 142.762 138.376 1.00 229.27 ?  327  VAL A CG1 1 
ATOM   1565 C CG2 . VAL A 1 327 ? 143.966 140.297 137.983 1.00 229.27 ?  327  VAL A CG2 1 
ATOM   1566 N N   . THR A 1 328 ? 140.691 140.614 137.000 1.00 244.65 ?  328  THR A N   1 
ATOM   1567 C CA  . THR A 1 328 ? 139.668 139.918 136.196 1.00 244.65 ?  328  THR A CA  1 
ATOM   1568 C C   . THR A 1 328 ? 138.206 140.123 136.586 1.00 244.65 ?  328  THR A C   1 
ATOM   1569 O O   . THR A 1 328 ? 137.862 141.064 137.302 1.00 244.65 ?  328  THR A O   1 
ATOM   1570 C CB  . THR A 1 328 ? 139.960 138.400 136.019 1.00 244.65 ?  328  THR A CB  1 
ATOM   1571 O OG1 . THR A 1 328 ? 139.662 137.688 137.228 1.00 244.65 ?  328  THR A OG1 1 
ATOM   1572 C CG2 . THR A 1 328 ? 141.411 138.159 135.620 1.00 244.65 ?  328  THR A CG2 1 
ATOM   1573 N N   . ILE A 1 329 ? 137.334 139.268 136.066 1.00 242.79 ?  329  ILE A N   1 
ATOM   1574 C CA  . ILE A 1 329 ? 135.912 139.367 136.375 1.00 242.79 ?  329  ILE A CA  1 
ATOM   1575 C C   . ILE A 1 329 ? 135.439 137.960 136.624 1.00 242.79 ?  329  ILE A C   1 
ATOM   1576 O O   . ILE A 1 329 ? 134.286 137.739 136.974 1.00 242.79 ?  329  ILE A O   1 
ATOM   1577 C CB  . ILE A 1 329 ? 135.114 139.971 135.215 1.00 242.79 ?  329  ILE A CB  1 
ATOM   1578 C CG1 . ILE A 1 329 ? 135.828 139.695 133.903 1.00 242.79 ?  329  ILE A CG1 1 
ATOM   1579 C CG2 . ILE A 1 329 ? 134.975 141.473 135.388 1.00 242.79 ?  329  ILE A CG2 1 
ATOM   1580 C CD1 . ILE A 1 329 ? 136.130 140.945 133.117 1.00 242.79 ?  329  ILE A CD1 1 
ATOM   1581 N N   . THR A 1 330 ? 136.329 136.997 136.423 1.00 225.17 ?  330  THR A N   1 
ATOM   1582 C CA  . THR A 1 330 ? 135.986 135.624 136.729 1.00 225.17 ?  330  THR A CA  1 
ATOM   1583 C C   . THR A 1 330 ? 136.164 135.483 138.224 1.00 225.17 ?  330  THR A C   1 
ATOM   1584 O O   . THR A 1 330 ? 135.443 134.730 138.869 1.00 225.17 ?  330  THR A O   1 
ATOM   1585 C CB  . THR A 1 330 ? 136.901 134.623 135.999 1.00 225.17 ?  330  THR A CB  1 
ATOM   1586 O OG1 . THR A 1 330 ? 137.682 133.896 136.956 1.00 225.17 ?  330  THR A OG1 1 
ATOM   1587 C CG2 . THR A 1 330 ? 137.833 135.341 135.039 1.00 225.17 ?  330  THR A CG2 1 
ATOM   1588 N N   . ALA A 1 331 ? 137.130 136.208 138.780 1.00 212.90 ?  331  ALA A N   1 
ATOM   1589 C CA  . ALA A 1 331 ? 137.341 136.187 140.219 1.00 212.90 ?  331  ALA A CA  1 
ATOM   1590 C C   . ALA A 1 331 ? 136.080 136.651 140.892 1.00 212.90 ?  331  ALA A C   1 
ATOM   1591 O O   . ALA A 1 331 ? 135.615 136.038 141.851 1.00 212.90 ?  331  ALA A O   1 
ATOM   1592 C CB  . ALA A 1 331 ? 138.468 137.125 140.589 1.00 212.90 ?  331  ALA A CB  1 
ATOM   1593 N N   . LEU A 1 332 ? 135.518 137.743 140.387 1.00 197.67 ?  332  LEU A N   1 
ATOM   1594 C CA  . LEU A 1 332 ? 134.323 138.301 140.999 1.00 197.67 ?  332  LEU A CA  1 
ATOM   1595 C C   . LEU A 1 332 ? 133.099 137.797 140.267 1.00 197.67 ?  332  LEU A C   1 
ATOM   1596 O O   . LEU A 1 332 ? 133.186 136.798 139.552 1.00 197.67 ?  332  LEU A O   1 
ATOM   1597 C CB  . LEU A 1 332 ? 134.359 139.829 140.967 1.00 197.67 ?  332  LEU A CB  1 
ATOM   1598 C CG  . LEU A 1 332 ? 135.513 140.501 140.216 1.00 197.67 ?  332  LEU A CG  1 
ATOM   1599 C CD1 . LEU A 1 332 ? 135.013 141.726 139.469 1.00 197.67 ?  332  LEU A CD1 1 
ATOM   1600 C CD2 . LEU A 1 332 ? 136.635 140.889 141.168 1.00 197.67 ?  332  LEU A CD2 1 
ATOM   1601 N N   . PHE A 1 333 ? 131.968 138.477 140.439 1.00 196.18 ?  333  PHE A N   1 
ATOM   1602 C CA  . PHE A 1 333 ? 130.716 138.090 139.777 1.00 196.18 ?  333  PHE A CA  1 
ATOM   1603 C C   . PHE A 1 333 ? 130.258 136.712 140.233 1.00 196.18 ?  333  PHE A C   1 
ATOM   1604 O O   . PHE A 1 333 ? 129.161 136.288 139.887 1.00 196.18 ?  333  PHE A O   1 
ATOM   1605 C CB  . PHE A 1 333 ? 130.817 138.117 138.240 1.00 196.18 ?  333  PHE A CB  1 
ATOM   1606 C CG  . PHE A 1 333 ? 131.074 139.478 137.644 1.00 196.18 ?  333  PHE A CG  1 
ATOM   1607 C CD1 . PHE A 1 333 ? 131.394 140.574 138.429 1.00 196.18 ?  333  PHE A CD1 1 
ATOM   1608 C CD2 . PHE A 1 333 ? 130.997 139.651 136.274 1.00 196.18 ?  333  PHE A CD2 1 
ATOM   1609 C CE1 . PHE A 1 333 ? 131.635 141.806 137.861 1.00 196.18 ?  333  PHE A CE1 1 
ATOM   1610 C CE2 . PHE A 1 333 ? 131.230 140.883 135.699 1.00 196.18 ?  333  PHE A CE2 1 
ATOM   1611 C CZ  . PHE A 1 333 ? 131.550 141.962 136.494 1.00 196.18 ?  333  PHE A CZ  1 
ATOM   1612 N N   . ARG A 1 334 ? 131.081 136.015 141.012 1.00 237.12 ?  334  ARG A N   1 
ATOM   1613 C CA  . ARG A 1 334 ? 130.740 134.685 141.449 1.00 237.12 ?  334  ARG A CA  1 
ATOM   1614 C C   . ARG A 1 334 ? 129.707 134.826 142.539 1.00 237.12 ?  334  ARG A C   1 
ATOM   1615 O O   . ARG A 1 334 ? 129.989 135.373 143.602 1.00 237.12 ?  334  ARG A O   1 
ATOM   1616 C CB  . ARG A 1 334 ? 131.976 133.942 141.942 1.00 237.12 ?  334  ARG A CB  1 
ATOM   1617 C CG  . ARG A 1 334 ? 132.371 132.768 141.063 1.00 237.12 ?  334  ARG A CG  1 
ATOM   1618 C CD  . ARG A 1 334 ? 132.485 133.183 139.608 1.00 237.12 ?  334  ARG A CD  1 
ATOM   1619 N NE  . ARG A 1 334 ? 133.061 132.132 138.779 1.00 237.12 ?  334  ARG A NE  1 
ATOM   1620 C CZ  . ARG A 1 334 ? 133.402 132.288 137.505 1.00 237.12 ?  334  ARG A CZ  1 
ATOM   1621 N NH1 . ARG A 1 334 ? 133.224 133.456 136.906 1.00 237.12 1  334  ARG A NH1 1 
ATOM   1622 N NH2 . ARG A 1 334 ? 133.920 131.275 136.827 1.00 237.12 ?  334  ARG A NH2 1 
ATOM   1623 N N   . THR A 1 335 ? 128.506 134.342 142.278 1.00 241.14 ?  335  THR A N   1 
ATOM   1624 C CA  . THR A 1 335 ? 127.414 134.458 143.224 1.00 241.14 ?  335  THR A CA  1 
ATOM   1625 C C   . THR A 1 335 ? 127.325 133.319 144.207 1.00 241.14 ?  335  THR A C   1 
ATOM   1626 O O   . THR A 1 335 ? 127.783 132.214 143.934 1.00 241.14 ?  335  THR A O   1 
ATOM   1627 C CB  . THR A 1 335 ? 126.080 134.557 142.499 1.00 241.14 ?  335  THR A CB  1 
ATOM   1628 O OG1 . THR A 1 335 ? 125.877 133.374 141.726 1.00 241.14 ?  335  THR A OG1 1 
ATOM   1629 C CG2 . THR A 1 335 ? 126.072 135.760 141.605 1.00 241.14 ?  335  THR A CG2 1 
ATOM   1630 N N   . ASN A 1 336 ? 126.764 133.596 145.378 1.00 222.54 ?  336  ASN A N   1 
ATOM   1631 C CA  . ASN A 1 336 ? 126.651 132.584 146.413 1.00 222.54 ?  336  ASN A CA  1 
ATOM   1632 C C   . ASN A 1 336 ? 125.202 132.483 146.811 1.00 222.54 ?  336  ASN A C   1 
ATOM   1633 O O   . ASN A 1 336 ? 124.852 132.701 147.965 1.00 222.54 ?  336  ASN A O   1 
ATOM   1634 C CB  . ASN A 1 336 ? 127.495 132.964 147.629 1.00 222.54 ?  336  ASN A CB  1 
ATOM   1635 C CG  . ASN A 1 336 ? 128.648 133.886 147.281 1.00 222.54 ?  336  ASN A CG  1 
ATOM   1636 O OD1 . ASN A 1 336 ? 129.633 133.464 146.675 1.00 222.54 ?  336  ASN A OD1 1 
ATOM   1637 N ND2 . ASN A 1 336 ? 128.532 135.152 147.665 1.00 222.54 ?  336  ASN A ND2 1 
ATOM   1638 N N   . PHE A 1 337 ? 124.350 132.165 145.848 1.00 245.34 ?  337  PHE A N   1 
ATOM   1639 C CA  . PHE A 1 337 ? 122.925 132.067 146.121 1.00 245.34 ?  337  PHE A CA  1 
ATOM   1640 C C   . PHE A 1 337 ? 122.616 130.704 146.675 1.00 245.34 ?  337  PHE A C   1 
ATOM   1641 O O   . PHE A 1 337 ? 123.011 129.691 146.107 1.00 245.34 ?  337  PHE A O   1 
ATOM   1642 C CB  . PHE A 1 337 ? 122.106 132.272 144.852 1.00 245.34 ?  337  PHE A CB  1 
ATOM   1643 C CG  . PHE A 1 337 ? 122.326 133.595 144.188 1.00 245.34 ?  337  PHE A CG  1 
ATOM   1644 C CD1 . PHE A 1 337 ? 122.625 134.723 144.930 1.00 245.34 ?  337  PHE A CD1 1 
ATOM   1645 C CD2 . PHE A 1 337 ? 122.219 133.709 142.817 1.00 245.34 ?  337  PHE A CD2 1 
ATOM   1646 C CE1 . PHE A 1 337 ? 122.825 135.935 144.316 1.00 245.34 ?  337  PHE A CE1 1 
ATOM   1647 C CE2 . PHE A 1 337 ? 122.415 134.920 142.198 1.00 245.34 ?  337  PHE A CE2 1 
ATOM   1648 C CZ  . PHE A 1 337 ? 122.721 136.034 142.950 1.00 245.34 ?  337  PHE A CZ  1 
ATOM   1649 N N   . ARG A 1 338 ? 121.852 130.645 147.760 1.00 255.26 ?  338  ARG A N   1 
ATOM   1650 C CA  . ARG A 1 338 ? 121.418 129.350 148.280 1.00 255.26 ?  338  ARG A CA  1 
ATOM   1651 C C   . ARG A 1 338 ? 120.005 129.118 147.785 1.00 255.26 ?  338  ARG A C   1 
ATOM   1652 O O   . ARG A 1 338 ? 119.047 129.601 148.383 1.00 255.26 ?  338  ARG A O   1 
ATOM   1653 C CB  . ARG A 1 338 ? 121.453 129.324 149.805 1.00 255.26 ?  338  ARG A CB  1 
ATOM   1654 C CG  . ARG A 1 338 ? 122.139 128.100 150.397 1.00 255.26 ?  338  ARG A CG  1 
ATOM   1655 C CD  . ARG A 1 338 ? 121.260 126.854 150.367 1.00 255.26 ?  338  ARG A CD  1 
ATOM   1656 N NE  . ARG A 1 338 ? 119.841 127.151 150.558 1.00 255.26 ?  338  ARG A NE  1 
ATOM   1657 C CZ  . ARG A 1 338 ? 118.852 126.413 150.063 1.00 255.26 ?  338  ARG A CZ  1 
ATOM   1658 N NH1 . ARG A 1 338 ? 117.591 126.758 150.280 1.00 255.26 1  338  ARG A NH1 1 
ATOM   1659 N NH2 . ARG A 1 338 ? 119.125 125.330 149.351 1.00 255.26 ?  338  ARG A NH2 1 
ATOM   1660 N N   . MET A 1 339 ? 119.864 128.379 146.693 1.00 275.55 ?  339  MET A N   1 
ATOM   1661 C CA  . MET A 1 339 ? 118.542 128.174 146.113 1.00 275.55 ?  339  MET A CA  1 
ATOM   1662 C C   . MET A 1 339 ? 117.977 126.791 146.382 1.00 275.55 ?  339  MET A C   1 
ATOM   1663 O O   . MET A 1 339 ? 118.702 125.800 146.327 1.00 275.55 ?  339  MET A O   1 
ATOM   1664 C CB  . MET A 1 339 ? 118.590 128.441 144.607 1.00 275.55 ?  339  MET A CB  1 
ATOM   1665 C CG  . MET A 1 339 ? 117.281 128.932 144.008 1.00 275.55 ?  339  MET A CG  1 
ATOM   1666 S SD  . MET A 1 339 ? 116.875 130.605 144.535 1.00 275.55 ?  339  MET A SD  1 
ATOM   1667 C CE  . MET A 1 339 ? 118.494 131.363 144.471 1.00 275.55 ?  339  MET A CE  1 
ATOM   1668 N N   . ASP A 1 340 ? 116.682 126.721 146.671 1.00 278.57 ?  340  ASP A N   1 
ATOM   1669 C CA  . ASP A 1 340 ? 116.058 125.424 146.882 1.00 278.57 ?  340  ASP A CA  1 
ATOM   1670 C C   . ASP A 1 340 ? 115.811 124.708 145.574 1.00 278.57 ?  340  ASP A C   1 
ATOM   1671 O O   . ASP A 1 340 ? 115.476 125.337 144.572 1.00 278.57 ?  340  ASP A O   1 
ATOM   1672 C CB  . ASP A 1 340 ? 114.780 125.526 147.702 1.00 278.57 ?  340  ASP A CB  1 
ATOM   1673 C CG  . ASP A 1 340 ? 114.547 124.296 148.556 1.00 278.57 ?  340  ASP A CG  1 
ATOM   1674 O OD1 . ASP A 1 340 ? 115.484 123.889 149.275 1.00 278.57 ?  340  ASP A OD1 1 
ATOM   1675 O OD2 . ASP A 1 340 ? 113.438 123.726 148.495 1.00 278.57 -1 340  ASP A OD2 1 
ATOM   1676 N N   . PHE A 1 341 ? 115.956 123.393 145.583 1.00 303.84 ?  341  PHE A N   1 
ATOM   1677 C CA  . PHE A 1 341 ? 115.828 122.597 144.357 1.00 303.84 ?  341  PHE A CA  1 
ATOM   1678 C C   . PHE A 1 341 ? 114.649 122.779 143.386 1.00 303.84 ?  341  PHE A C   1 
ATOM   1679 O O   . PHE A 1 341 ? 114.876 122.978 142.193 1.00 303.84 ?  341  PHE A O   1 
ATOM   1680 C CB  . PHE A 1 341 ? 116.033 121.100 144.675 1.00 303.84 ?  341  PHE A CB  1 
ATOM   1681 C CG  . PHE A 1 341 ? 116.281 120.812 146.135 1.00 303.84 ?  341  PHE A CG  1 
ATOM   1682 C CD1 . PHE A 1 341 ? 117.569 120.824 146.652 1.00 303.84 ?  341  PHE A CD1 1 
ATOM   1683 C CD2 . PHE A 1 341 ? 115.228 120.509 146.986 1.00 303.84 ?  341  PHE A CD2 1 
ATOM   1684 C CE1 . PHE A 1 341 ? 117.796 120.565 147.989 1.00 303.84 ?  341  PHE A CE1 1 
ATOM   1685 C CE2 . PHE A 1 341 ? 115.450 120.249 148.323 1.00 303.84 ?  341  PHE A CE2 1 
ATOM   1686 C CZ  . PHE A 1 341 ? 116.735 120.273 148.824 1.00 303.84 ?  341  PHE A CZ  1 
ATOM   1687 N N   . PRO A 1 342 ? 113.390 122.715 143.867 1.00 254.20 ?  342  PRO A N   1 
ATOM   1688 C CA  . PRO A 1 342 ? 112.315 122.789 142.864 1.00 254.20 ?  342  PRO A CA  1 
ATOM   1689 C C   . PRO A 1 342 ? 112.054 124.141 142.204 1.00 254.20 ?  342  PRO A C   1 
ATOM   1690 O O   . PRO A 1 342 ? 111.418 124.095 141.152 1.00 254.20 ?  342  PRO A O   1 
ATOM   1691 C CB  . PRO A 1 342 ? 111.068 122.345 143.646 1.00 254.20 ?  342  PRO A CB  1 
ATOM   1692 C CG  . PRO A 1 342 ? 111.576 121.751 144.918 1.00 254.20 ?  342  PRO A CG  1 
ATOM   1693 C CD  . PRO A 1 342 ? 112.827 122.511 145.211 1.00 254.20 ?  342  PRO A CD  1 
ATOM   1694 N N   . PHE A 1 343 ? 112.501 125.263 142.771 1.00 275.51 ?  343  PHE A N   1 
ATOM   1695 C CA  . PHE A 1 343 ? 112.224 126.621 142.247 1.00 275.51 ?  343  PHE A CA  1 
ATOM   1696 C C   . PHE A 1 343 ? 110.772 127.084 142.406 1.00 275.51 ?  343  PHE A C   1 
ATOM   1697 O O   . PHE A 1 343 ? 109.836 126.387 142.024 1.00 275.51 ?  343  PHE A O   1 
ATOM   1698 C CB  . PHE A 1 343 ? 112.742 126.856 140.807 1.00 275.51 ?  343  PHE A CB  1 
ATOM   1699 C CG  . PHE A 1 343 ? 112.207 128.111 140.164 1.00 275.51 ?  343  PHE A CG  1 
ATOM   1700 C CD1 . PHE A 1 343 ? 112.615 129.363 140.604 1.00 275.51 ?  343  PHE A CD1 1 
ATOM   1701 C CD2 . PHE A 1 343 ? 111.288 128.041 139.127 1.00 275.51 ?  343  PHE A CD2 1 
ATOM   1702 C CE1 . PHE A 1 343 ? 112.108 130.513 140.036 1.00 275.51 ?  343  PHE A CE1 1 
ATOM   1703 C CE2 . PHE A 1 343 ? 110.785 129.190 138.549 1.00 275.51 ?  343  PHE A CE2 1 
ATOM   1704 C CZ  . PHE A 1 343 ? 111.193 130.427 139.004 1.00 275.51 ?  343  PHE A CZ  1 
ATOM   1705 N N   . ASP A 1 344 ? 110.583 128.269 142.975 1.00 271.16 ?  344  ASP A N   1 
ATOM   1706 C CA  . ASP A 1 344 ? 109.243 128.807 143.126 1.00 271.16 ?  344  ASP A CA  1 
ATOM   1707 C C   . ASP A 1 344 ? 108.690 129.212 141.783 1.00 271.16 ?  344  ASP A C   1 
ATOM   1708 O O   . ASP A 1 344 ? 109.044 130.254 141.266 1.00 271.16 ?  344  ASP A O   1 
ATOM   1709 C CB  . ASP A 1 344 ? 109.279 130.034 144.021 1.00 271.16 ?  344  ASP A CB  1 
ATOM   1710 C CG  . ASP A 1 344 ? 107.925 130.384 144.581 1.00 271.16 ?  344  ASP A CG  1 
ATOM   1711 O OD1 . ASP A 1 344 ? 107.443 129.670 145.477 1.00 271.16 ?  344  ASP A OD1 1 
ATOM   1712 O OD2 . ASP A 1 344 ? 107.344 131.382 144.129 1.00 271.16 -1 344  ASP A OD2 1 
ATOM   1713 N N   . LEU A 1 345 ? 107.774 128.424 141.239 1.00 247.04 ?  345  LEU A N   1 
ATOM   1714 C CA  . LEU A 1 345 ? 107.187 128.728 139.941 1.00 247.04 ?  345  LEU A CA  1 
ATOM   1715 C C   . LEU A 1 345 ? 106.263 129.933 139.974 1.00 247.04 ?  345  LEU A C   1 
ATOM   1716 O O   . LEU A 1 345 ? 105.769 130.351 138.937 1.00 247.04 ?  345  LEU A O   1 
ATOM   1717 C CB  . LEU A 1 345 ? 106.424 127.522 139.400 1.00 247.04 ?  345  LEU A CB  1 
ATOM   1718 C CG  . LEU A 1 345 ? 107.084 126.596 138.378 1.00 247.04 ?  345  LEU A CG  1 
ATOM   1719 C CD1 . LEU A 1 345 ? 107.663 127.372 137.208 1.00 247.04 ?  345  LEU A CD1 1 
ATOM   1720 C CD2 . LEU A 1 345 ? 108.130 125.691 139.010 1.00 247.04 ?  345  LEU A CD2 1 
ATOM   1721 N N   . LYS A 1 346 ? 105.998 130.480 141.153 1.00 266.65 ?  346  LYS A N   1 
ATOM   1722 C CA  . LYS A 1 346 ? 105.195 131.683 141.237 1.00 266.65 ?  346  LYS A CA  1 
ATOM   1723 C C   . LYS A 1 346 ? 106.080 132.900 141.010 1.00 266.65 ?  346  LYS A C   1 
ATOM   1724 O O   . LYS A 1 346 ? 105.571 133.999 140.810 1.00 266.65 ?  346  LYS A O   1 
ATOM   1725 C CB  . LYS A 1 346 ? 104.488 131.762 142.582 1.00 266.65 ?  346  LYS A CB  1 
ATOM   1726 C CG  . LYS A 1 346 ? 102.997 131.494 142.516 1.00 266.65 ?  346  LYS A CG  1 
ATOM   1727 C CD  . LYS A 1 346 ? 102.260 132.294 143.573 1.00 266.65 ?  346  LYS A CD  1 
ATOM   1728 C CE  . LYS A 1 346 ? 101.455 131.392 144.492 1.00 266.65 ?  346  LYS A CE  1 
ATOM   1729 N NZ  . LYS A 1 346 ? 101.791 131.619 145.925 1.00 266.65 1  346  LYS A NZ  1 
ATOM   1730 N N   . GLU A 1 347 ? 107.398 132.724 141.055 1.00 288.93 ?  347  GLU A N   1 
ATOM   1731 C CA  . GLU A 1 347 ? 108.306 133.815 140.753 1.00 288.93 ?  347  GLU A CA  1 
ATOM   1732 C C   . GLU A 1 347 ? 108.550 133.834 139.264 1.00 288.93 ?  347  GLU A C   1 
ATOM   1733 O O   . GLU A 1 347 ? 109.017 134.828 138.734 1.00 288.93 ?  347  GLU A O   1 
ATOM   1734 C CB  . GLU A 1 347 ? 109.620 133.634 141.495 1.00 288.93 ?  347  GLU A CB  1 
ATOM   1735 C CG  . GLU A 1 347 ? 109.490 133.678 143.003 1.00 288.93 ?  347  GLU A CG  1 
ATOM   1736 C CD  . GLU A 1 347 ? 110.831 133.643 143.701 1.00 288.93 ?  347  GLU A CD  1 
ATOM   1737 O OE1 . GLU A 1 347 ? 110.860 133.400 144.925 1.00 288.93 ?  347  GLU A OE1 1 
ATOM   1738 O OE2 . GLU A 1 347 ? 111.857 133.859 143.026 1.00 288.93 -1 347  GLU A OE2 1 
ATOM   1739 N N   . LEU A 1 348 ? 108.235 132.739 138.581 1.00 269.76 ?  348  LEU A N   1 
ATOM   1740 C CA  . LEU A 1 348 ? 108.364 132.698 137.123 1.00 269.76 ?  348  LEU A CA  1 
ATOM   1741 C C   . LEU A 1 348 ? 107.641 133.833 136.388 1.00 269.76 ?  348  LEU A C   1 
ATOM   1742 O O   . LEU A 1 348 ? 108.190 134.372 135.444 1.00 269.76 ?  348  LEU A O   1 
ATOM   1743 C CB  . LEU A 1 348 ? 107.988 131.317 136.560 1.00 269.76 ?  348  LEU A CB  1 
ATOM   1744 C CG  . LEU A 1 348 ? 108.757 130.728 135.375 1.00 269.76 ?  348  LEU A CG  1 
ATOM   1745 C CD1 . LEU A 1 348 ? 107.894 130.709 134.125 1.00 269.76 ?  348  LEU A CD1 1 
ATOM   1746 C CD2 . LEU A 1 348 ? 110.075 131.438 135.111 1.00 269.76 ?  348  LEU A CD2 1 
ATOM   1747 N N   . PRO A 1 349 ? 106.401 134.194 136.791 1.00 289.85 ?  349  PRO A N   1 
ATOM   1748 C CA  . PRO A 1 349 ? 105.806 135.360 136.129 1.00 289.85 ?  349  PRO A CA  1 
ATOM   1749 C C   . PRO A 1 349 ? 106.668 136.623 136.194 1.00 289.85 ?  349  PRO A C   1 
ATOM   1750 O O   . PRO A 1 349 ? 106.692 137.367 135.225 1.00 289.85 ?  349  PRO A O   1 
ATOM   1751 C CB  . PRO A 1 349 ? 104.529 135.580 136.926 1.00 289.85 ?  349  PRO A CB  1 
ATOM   1752 C CG  . PRO A 1 349 ? 104.106 134.213 137.301 1.00 289.85 ?  349  PRO A CG  1 
ATOM   1753 C CD  . PRO A 1 349 ? 105.356 133.406 137.481 1.00 289.85 ?  349  PRO A CD  1 
ATOM   1754 N N   . ALA A 1 350 ? 107.357 136.858 137.305 1.00 309.05 ?  350  ALA A N   1 
ATOM   1755 C CA  . ALA A 1 350 ? 108.210 138.031 137.443 1.00 309.05 ?  350  ALA A CA  1 
ATOM   1756 C C   . ALA A 1 350 ? 109.461 137.932 136.602 1.00 309.05 ?  350  ALA A C   1 
ATOM   1757 O O   . ALA A 1 350 ? 109.947 138.935 136.105 1.00 309.05 ?  350  ALA A O   1 
ATOM   1758 C CB  . ALA A 1 350 ? 108.579 138.243 138.891 1.00 309.05 ?  350  ALA A CB  1 
ATOM   1759 N N   . PHE A 1 351 ? 109.992 136.730 136.443 1.00 310.03 ?  351  PHE A N   1 
ATOM   1760 C CA  . PHE A 1 351 ? 111.162 136.535 135.604 1.00 310.03 ?  351  PHE A CA  1 
ATOM   1761 C C   . PHE A 1 351 ? 110.771 136.673 134.150 1.00 310.03 ?  351  PHE A C   1 
ATOM   1762 O O   . PHE A 1 351 ? 111.556 137.140 133.335 1.00 310.03 ?  351  PHE A O   1 
ATOM   1763 C CB  . PHE A 1 351 ? 111.757 135.160 135.851 1.00 310.03 ?  351  PHE A CB  1 
ATOM   1764 C CG  . PHE A 1 351 ? 112.483 135.046 137.149 1.00 310.03 ?  351  PHE A CG  1 
ATOM   1765 C CD1 . PHE A 1 351 ? 113.564 135.850 137.417 1.00 310.03 ?  351  PHE A CD1 1 
ATOM   1766 C CD2 . PHE A 1 351 ? 112.083 134.136 138.100 1.00 310.03 ?  351  PHE A CD2 1 
ATOM   1767 C CE1 . PHE A 1 351 ? 114.244 135.737 138.609 1.00 310.03 ?  351  PHE A CE1 1 
ATOM   1768 C CE2 . PHE A 1 351 ? 112.751 134.030 139.300 1.00 310.03 ?  351  PHE A CE2 1 
ATOM   1769 C CZ  . PHE A 1 351 ? 113.838 134.825 139.552 1.00 310.03 ?  351  PHE A CZ  1 
ATOM   1770 N N   . ALA A 1 352 ? 109.558 136.262 133.816 1.00 330.93 ?  352  ALA A N   1 
ATOM   1771 C CA  . ALA A 1 352 ? 109.078 136.412 132.460 1.00 330.93 ?  352  ALA A CA  1 
ATOM   1772 C C   . ALA A 1 352 ? 108.855 137.881 132.191 1.00 330.93 ?  352  ALA A C   1 
ATOM   1773 O O   . ALA A 1 352 ? 109.107 138.346 131.090 1.00 330.93 ?  352  ALA A O   1 
ATOM   1774 C CB  . ALA A 1 352 ? 107.785 135.646 132.276 1.00 330.93 ?  352  ALA A CB  1 
ATOM   1775 N N   . ALA A 1 353 ? 108.389 138.615 133.197 1.00 337.56 ?  353  ALA A N   1 
ATOM   1776 C CA  . ALA A 1 353 ? 108.168 140.046 133.043 1.00 337.56 ?  353  ALA A CA  1 
ATOM   1777 C C   . ALA A 1 353 ? 109.485 140.755 132.847 1.00 337.56 ?  353  ALA A C   1 
ATOM   1778 O O   . ALA A 1 353 ? 109.559 141.687 132.061 1.00 337.56 ?  353  ALA A O   1 
ATOM   1779 C CB  . ALA A 1 353 ? 107.444 140.606 134.251 1.00 337.56 ?  353  ALA A CB  1 
ATOM   1780 N N   . ILE A 1 354 ? 110.523 140.325 133.557 1.00 316.46 ?  354  ILE A N   1 
ATOM   1781 C CA  . ILE A 1 354 ? 111.844 140.900 133.374 1.00 316.46 ?  354  ILE A CA  1 
ATOM   1782 C C   . ILE A 1 354 ? 112.190 140.761 131.912 1.00 316.46 ?  354  ILE A C   1 
ATOM   1783 O O   . ILE A 1 354 ? 112.508 141.738 131.274 1.00 316.46 ?  354  ILE A O   1 
ATOM   1784 C CB  . ILE A 1 354 ? 112.904 140.185 134.235 1.00 316.46 ?  354  ILE A CB  1 
ATOM   1785 C CG1 . ILE A 1 354 ? 112.828 140.635 135.686 1.00 316.46 ?  354  ILE A CG1 1 
ATOM   1786 C CG2 . ILE A 1 354 ? 114.311 140.443 133.731 1.00 316.46 ?  354  ILE A CG2 1 
ATOM   1787 C CD1 . ILE A 1 354 ? 113.864 139.967 136.558 1.00 316.46 ?  354  ILE A CD1 1 
ATOM   1788 N N   . GLY A 1 355 ? 112.079 139.555 131.366 1.00 313.43 ?  355  GLY A N   1 
ATOM   1789 C CA  . GLY A 1 355 ? 112.379 139.330 129.969 1.00 313.43 ?  355  GLY A CA  1 
ATOM   1790 C C   . GLY A 1 355 ? 111.643 140.234 129.017 1.00 313.43 ?  355  GLY A C   1 
ATOM   1791 O O   . GLY A 1 355 ? 112.259 140.890 128.198 1.00 313.43 ?  355  GLY A O   1 
ATOM   1792 N N   . ILE A 1 356 ? 110.325 140.283 129.122 1.00 339.55 ?  356  ILE A N   1 
ATOM   1793 C CA  . ILE A 1 356 ? 109.531 141.145 128.261 1.00 339.55 ?  356  ILE A CA  1 
ATOM   1794 C C   . ILE A 1 356 ? 110.018 142.578 128.330 1.00 339.55 ?  356  ILE A C   1 
ATOM   1795 O O   . ILE A 1 356 ? 110.307 143.189 127.303 1.00 339.55 ?  356  ILE A O   1 
ATOM   1796 C CB  . ILE A 1 356 ? 108.039 141.089 128.638 1.00 339.55 ?  356  ILE A CB  1 
ATOM   1797 C CG1 . ILE A 1 356 ? 107.513 139.663 128.510 1.00 339.55 ?  356  ILE A CG1 1 
ATOM   1798 C CG2 . ILE A 1 356 ? 107.214 142.014 127.757 1.00 339.55 ?  356  ILE A CG2 1 
ATOM   1799 C CD1 . ILE A 1 356 ? 107.149 139.274 127.096 1.00 339.55 ?  356  ILE A CD1 1 
ATOM   1800 N N   . CYS A 1 357 ? 110.144 143.112 129.538 1.00 342.37 ?  357  CYS A N   1 
ATOM   1801 C CA  . CYS A 1 357 ? 110.572 144.495 129.705 1.00 342.37 ?  357  CYS A CA  1 
ATOM   1802 C C   . CYS A 1 357 ? 112.011 144.740 129.294 1.00 342.37 ?  357  CYS A C   1 
ATOM   1803 O O   . CYS A 1 357 ? 112.327 145.802 128.799 1.00 342.37 ?  357  CYS A O   1 
ATOM   1804 C CB  . CYS A 1 357 ? 110.341 144.951 131.137 1.00 342.37 ?  357  CYS A CB  1 
ATOM   1805 S SG  . CYS A 1 357 ? 108.608 144.980 131.632 1.00 342.37 ?  357  CYS A SG  1 
ATOM   1806 N N   . CYS A 1 358 ? 112.881 143.758 129.474 1.00 330.10 ?  358  CYS A N   1 
ATOM   1807 C CA  . CYS A 1 358 ? 114.269 143.888 129.062 1.00 330.10 ?  358  CYS A CA  1 
ATOM   1808 C C   . CYS A 1 358 ? 114.371 143.859 127.560 1.00 330.10 ?  358  CYS A C   1 
ATOM   1809 O O   . CYS A 1 358 ? 115.301 144.413 127.004 1.00 330.10 ?  358  CYS A O   1 
ATOM   1810 C CB  . CYS A 1 358 ? 115.108 142.764 129.647 1.00 330.10 ?  358  CYS A CB  1 
ATOM   1811 S SG  . CYS A 1 358 ? 115.702 143.043 131.325 1.00 330.10 ?  358  CYS A SG  1 
ATOM   1812 N N   . GLY A 1 359 ? 113.424 143.214 126.892 1.00 335.59 ?  359  GLY A N   1 
ATOM   1813 C CA  . GLY A 1 359 ? 113.402 143.213 125.444 1.00 335.59 ?  359  GLY A CA  1 
ATOM   1814 C C   . GLY A 1 359 ? 112.955 144.559 124.958 1.00 335.59 ?  359  GLY A C   1 
ATOM   1815 O O   . GLY A 1 359 ? 113.476 145.071 123.977 1.00 335.59 ?  359  GLY A O   1 
ATOM   1816 N N   . LEU A 1 360 ? 111.990 145.148 125.646 1.00 355.91 ?  360  LEU A N   1 
ATOM   1817 C CA  . LEU A 1 360 ? 111.545 146.483 125.293 1.00 355.91 ?  360  LEU A CA  1 
ATOM   1818 C C   . LEU A 1 360 ? 112.678 147.463 125.487 1.00 355.91 ?  360  LEU A C   1 
ATOM   1819 O O   . LEU A 1 360 ? 112.971 148.246 124.597 1.00 355.91 ?  360  LEU A O   1 
ATOM   1820 C CB  . LEU A 1 360 ? 110.362 146.895 126.164 1.00 355.91 ?  360  LEU A CB  1 
ATOM   1821 C CG  . LEU A 1 360 ? 109.027 146.220 125.868 1.00 355.91 ?  360  LEU A CG  1 
ATOM   1822 C CD1 . LEU A 1 360 ? 108.158 146.176 127.114 1.00 355.91 ?  360  LEU A CD1 1 
ATOM   1823 C CD2 . LEU A 1 360 ? 108.313 146.947 124.744 1.00 355.91 ?  360  LEU A CD2 1 
ATOM   1824 N N   . LEU A 1 361 ? 113.333 147.409 126.638 1.00 288.30 ?  361  LEU A N   1 
ATOM   1825 C CA  . LEU A 1 361 ? 114.420 148.326 126.934 1.00 288.30 ?  361  LEU A CA  1 
ATOM   1826 C C   . LEU A 1 361 ? 115.652 148.045 126.107 1.00 288.30 ?  361  LEU A C   1 
ATOM   1827 O O   . LEU A 1 361 ? 116.439 148.940 125.853 1.00 288.30 ?  361  LEU A O   1 
ATOM   1828 C CB  . LEU A 1 361 ? 114.760 148.262 128.417 1.00 288.30 ?  361  LEU A CB  1 
ATOM   1829 C CG  . LEU A 1 361 ? 113.717 148.903 129.324 1.00 288.30 ?  361  LEU A CG  1 
ATOM   1830 C CD1 . LEU A 1 361 ? 113.751 148.280 130.710 1.00 288.30 ?  361  LEU A CD1 1 
ATOM   1831 C CD2 . LEU A 1 361 ? 113.916 150.408 129.381 1.00 288.30 ?  361  LEU A CD2 1 
ATOM   1832 N N   . GLY A 1 362 ? 115.828 146.805 125.680 1.00 272.11 ?  362  GLY A N   1 
ATOM   1833 C CA  . GLY A 1 362 ? 116.951 146.461 124.836 1.00 272.11 ?  362  GLY A CA  1 
ATOM   1834 C C   . GLY A 1 362 ? 116.765 147.126 123.507 1.00 272.11 ?  362  GLY A C   1 
ATOM   1835 O O   . GLY A 1 362 ? 117.703 147.677 122.954 1.00 272.11 ?  362  GLY A O   1 
ATOM   1836 N N   . ALA A 1 363 ? 115.543 147.101 122.997 1.00 285.87 ?  363  ALA A N   1 
ATOM   1837 C CA  . ALA A 1 363 ? 115.254 147.763 121.744 1.00 285.87 ?  363  ALA A CA  1 
ATOM   1838 C C   . ALA A 1 363 ? 115.364 149.268 121.892 1.00 285.87 ?  363  ALA A C   1 
ATOM   1839 O O   . ALA A 1 363 ? 115.869 149.930 121.005 1.00 285.87 ?  363  ALA A O   1 
ATOM   1840 C CB  . ALA A 1 363 ? 113.882 147.371 121.258 1.00 285.87 ?  363  ALA A CB  1 
ATOM   1841 N N   . VAL A 1 364 ? 114.910 149.816 123.014 1.00 252.87 ?  364  VAL A N   1 
ATOM   1842 C CA  . VAL A 1 364 ? 115.051 151.251 123.263 1.00 252.87 ?  364  VAL A CA  1 
ATOM   1843 C C   . VAL A 1 364 ? 116.524 151.648 123.264 1.00 252.87 ?  364  VAL A C   1 
ATOM   1844 O O   . VAL A 1 364 ? 116.889 152.638 122.649 1.00 252.87 ?  364  VAL A O   1 
ATOM   1845 C CB  . VAL A 1 364 ? 114.336 151.665 124.568 1.00 252.87 ?  364  VAL A CB  1 
ATOM   1846 C CG1 . VAL A 1 364 ? 114.714 153.072 124.998 1.00 252.87 ?  364  VAL A CG1 1 
ATOM   1847 C CG2 . VAL A 1 364 ? 112.831 151.577 124.391 1.00 252.87 ?  364  VAL A CG2 1 
ATOM   1848 N N   . PHE A 1 365 ? 117.377 150.865 123.915 1.00 248.26 ?  365  PHE A N   1 
ATOM   1849 C CA  . PHE A 1 365 ? 118.805 151.136 123.901 1.00 248.26 ?  365  PHE A CA  1 
ATOM   1850 C C   . PHE A 1 365 ? 119.294 151.188 122.475 1.00 248.26 ?  365  PHE A C   1 
ATOM   1851 O O   . PHE A 1 365 ? 119.879 152.176 122.072 1.00 248.26 ?  365  PHE A O   1 
ATOM   1852 C CB  . PHE A 1 365 ? 119.573 150.055 124.665 1.00 248.26 ?  365  PHE A CB  1 
ATOM   1853 C CG  . PHE A 1 365 ? 120.989 150.431 125.004 1.00 248.26 ?  365  PHE A CG  1 
ATOM   1854 C CD1 . PHE A 1 365 ? 122.023 150.208 124.103 1.00 248.26 ?  365  PHE A CD1 1 
ATOM   1855 C CD2 . PHE A 1 365 ? 121.292 150.990 126.231 1.00 248.26 ?  365  PHE A CD2 1 
ATOM   1856 C CE1 . PHE A 1 365 ? 123.320 150.557 124.412 1.00 248.26 ?  365  PHE A CE1 1 
ATOM   1857 C CE2 . PHE A 1 365 ? 122.588 151.337 126.548 1.00 248.26 ?  365  PHE A CE2 1 
ATOM   1858 C CZ  . PHE A 1 365 ? 123.604 151.118 125.639 1.00 248.26 ?  365  PHE A CZ  1 
ATOM   1859 N N   . VAL A 1 366 ? 119.068 150.121 121.715 1.00 255.93 ?  366  VAL A N   1 
ATOM   1860 C CA  . VAL A 1 366 ? 119.518 150.067 120.327 1.00 255.93 ?  366  VAL A CA  1 
ATOM   1861 C C   . VAL A 1 366 ? 119.037 151.279 119.550 1.00 255.93 ?  366  VAL A C   1 
ATOM   1862 O O   . VAL A 1 366 ? 119.833 151.958 118.909 1.00 255.93 ?  366  VAL A O   1 
ATOM   1863 C CB  . VAL A 1 366 ? 119.065 148.766 119.637 1.00 255.93 ?  366  VAL A CB  1 
ATOM   1864 C CG1 . VAL A 1 366 ? 119.448 148.768 118.172 1.00 255.93 ?  366  VAL A CG1 1 
ATOM   1865 C CG2 . VAL A 1 366 ? 119.688 147.563 120.322 1.00 255.93 ?  366  VAL A CG2 1 
ATOM   1866 N N   . TYR A 1 367 ? 117.748 151.576 119.634 1.00 277.07 ?  367  TYR A N   1 
ATOM   1867 C CA  . TYR A 1 367 ? 117.192 152.729 118.943 1.00 277.07 ?  367  TYR A CA  1 
ATOM   1868 C C   . TYR A 1 367 ? 117.882 154.015 119.325 1.00 277.07 ?  367  TYR A C   1 
ATOM   1869 O O   . TYR A 1 367 ? 118.381 154.719 118.467 1.00 277.07 ?  367  TYR A O   1 
ATOM   1870 C CB  . TYR A 1 367 ? 115.699 152.854 119.236 1.00 277.07 ?  367  TYR A CB  1 
ATOM   1871 C CG  . TYR A 1 367 ? 115.010 153.907 118.411 1.00 277.07 ?  367  TYR A CG  1 
ATOM   1872 C CD1 . TYR A 1 367 ? 114.753 153.698 117.069 1.00 277.07 ?  367  TYR A CD1 1 
ATOM   1873 C CD2 . TYR A 1 367 ? 114.620 155.113 118.974 1.00 277.07 ?  367  TYR A CD2 1 
ATOM   1874 C CE1 . TYR A 1 367 ? 114.126 154.659 116.305 1.00 277.07 ?  367  TYR A CE1 1 
ATOM   1875 C CE2 . TYR A 1 367 ? 113.995 156.081 118.219 1.00 277.07 ?  367  TYR A CE2 1 
ATOM   1876 C CZ  . TYR A 1 367 ? 113.751 155.848 116.885 1.00 277.07 ?  367  TYR A CZ  1 
ATOM   1877 O OH  . TYR A 1 367 ? 113.126 156.807 116.127 1.00 277.07 ?  367  TYR A OH  1 
ATOM   1878 N N   . LEU A 1 368 ? 117.921 154.325 120.609 1.00 258.19 ?  368  LEU A N   1 
ATOM   1879 C CA  . LEU A 1 368 ? 118.497 155.584 121.056 1.00 258.19 ?  368  LEU A CA  1 
ATOM   1880 C C   . LEU A 1 368 ? 119.979 155.698 120.763 1.00 258.19 ?  368  LEU A C   1 
ATOM   1881 O O   . LEU A 1 368 ? 120.469 156.781 120.482 1.00 258.19 ?  368  LEU A O   1 
ATOM   1882 C CB  . LEU A 1 368 ? 118.250 155.763 122.545 1.00 258.19 ?  368  LEU A CB  1 
ATOM   1883 C CG  . LEU A 1 368 ? 117.228 156.799 123.002 1.00 258.19 ?  368  LEU A CG  1 
ATOM   1884 C CD1 . LEU A 1 368 ? 116.132 157.004 121.970 1.00 258.19 ?  368  LEU A CD1 1 
ATOM   1885 C CD2 . LEU A 1 368 ? 116.642 156.384 124.341 1.00 258.19 ?  368  LEU A CD2 1 
ATOM   1886 N N   . HIS A 1 369 ? 120.695 154.586 120.829 1.00 221.21 ?  369  HIS A N   1 
ATOM   1887 C CA  . HIS A 1 369 ? 122.111 154.595 120.536 1.00 221.21 ?  369  HIS A CA  1 
ATOM   1888 C C   . HIS A 1 369 ? 122.310 154.907 119.073 1.00 221.21 ?  369  HIS A C   1 
ATOM   1889 O O   . HIS A 1 369 ? 123.169 155.697 118.724 1.00 221.21 ?  369  HIS A O   1 
ATOM   1890 C CB  . HIS A 1 369 ? 122.735 153.248 120.882 1.00 221.21 ?  369  HIS A CB  1 
ATOM   1891 C CG  . HIS A 1 369 ? 124.110 153.057 120.327 1.00 221.21 ?  369  HIS A CG  1 
ATOM   1892 N ND1 . HIS A 1 369 ? 125.221 153.658 120.873 1.00 221.21 ?  369  HIS A ND1 1 
ATOM   1893 C CD2 . HIS A 1 369 ? 124.552 152.336 119.269 1.00 221.21 ?  369  HIS A CD2 1 
ATOM   1894 C CE1 . HIS A 1 369 ? 126.289 153.314 120.177 1.00 221.21 ?  369  HIS A CE1 1 
ATOM   1895 N NE2 . HIS A 1 369 ? 125.911 152.510 119.201 1.00 221.21 ?  369  HIS A NE2 1 
ATOM   1896 N N   . ARG A 1 370 ? 121.509 154.296 118.210 1.00 225.90 ?  370  ARG A N   1 
ATOM   1897 C CA  . ARG A 1 370 ? 121.612 154.550 116.783 1.00 225.90 ?  370  ARG A CA  1 
ATOM   1898 C C   . ARG A 1 370 ? 121.198 155.977 116.487 1.00 225.90 ?  370  ARG A C   1 
ATOM   1899 O O   . ARG A 1 370 ? 121.778 156.625 115.638 1.00 225.90 ?  370  ARG A O   1 
ATOM   1900 C CB  . ARG A 1 370 ? 120.768 153.545 116.006 1.00 225.90 ?  370  ARG A CB  1 
ATOM   1901 C CG  . ARG A 1 370 ? 120.220 154.016 114.669 1.00 225.90 ?  370  ARG A CG  1 
ATOM   1902 C CD  . ARG A 1 370 ? 119.517 152.887 113.943 1.00 225.90 ?  370  ARG A CD  1 
ATOM   1903 N NE  . ARG A 1 370 ? 119.065 151.865 114.878 1.00 225.90 ?  370  ARG A NE  1 
ATOM   1904 C CZ  . ARG A 1 370 ? 117.796 151.673 115.217 1.00 225.90 ?  370  ARG A CZ  1 
ATOM   1905 N NH1 . ARG A 1 370 ? 116.846 152.433 114.696 1.00 225.90 1  370  ARG A NH1 1 
ATOM   1906 N NH2 . ARG A 1 370 ? 117.483 150.722 116.078 1.00 225.90 ?  370  ARG A NH2 1 
ATOM   1907 N N   . GLN A 1 371 ? 120.225 156.488 117.222 1.00 244.03 ?  371  GLN A N   1 
ATOM   1908 C CA  . GLN A 1 371 ? 119.770 157.848 117.009 1.00 244.03 ?  371  GLN A CA  1 
ATOM   1909 C C   . GLN A 1 371 ? 120.845 158.860 117.346 1.00 244.03 ?  371  GLN A C   1 
ATOM   1910 O O   . GLN A 1 371 ? 121.017 159.829 116.624 1.00 244.03 ?  371  GLN A O   1 
ATOM   1911 C CB  . GLN A 1 371 ? 118.496 158.126 117.808 1.00 244.03 ?  371  GLN A CB  1 
ATOM   1912 C CG  . GLN A 1 371 ? 117.184 157.943 117.047 1.00 244.03 ?  371  GLN A CG  1 
ATOM   1913 C CD  . GLN A 1 371 ? 117.289 157.063 115.808 1.00 244.03 ?  371  GLN A CD  1 
ATOM   1914 O OE1 . GLN A 1 371 ? 117.329 155.837 115.899 1.00 244.03 ?  371  GLN A OE1 1 
ATOM   1915 N NE2 . GLN A 1 371 ? 117.303 157.693 114.637 1.00 244.03 ?  371  GLN A NE2 1 
ATOM   1916 N N   . VAL A 1 372 ? 121.586 158.640 118.427 1.00 207.35 ?  372  VAL A N   1 
ATOM   1917 C CA  . VAL A 1 372 ? 122.684 159.542 118.757 1.00 207.35 ?  372  VAL A CA  1 
ATOM   1918 C C   . VAL A 1 372 ? 123.884 159.280 117.852 1.00 207.35 ?  372  VAL A C   1 
ATOM   1919 O O   . VAL A 1 372 ? 124.618 160.199 117.518 1.00 207.35 ?  372  VAL A O   1 
ATOM   1920 C CB  . VAL A 1 372 ? 123.020 159.547 120.274 1.00 207.35 ?  372  VAL A CB  1 
ATOM   1921 C CG1 . VAL A 1 372 ? 123.699 158.276 120.721 1.00 207.35 ?  372  VAL A CG1 1 
ATOM   1922 C CG2 . VAL A 1 372 ? 123.848 160.764 120.659 1.00 207.35 ?  372  VAL A CG2 1 
ATOM   1923 N N   . MET A 1 373 ? 124.058 158.044 117.402 1.00 218.54 ?  373  MET A N   1 
ATOM   1924 C CA  . MET A 1 373 ? 125.145 157.731 116.487 1.00 218.54 ?  373  MET A CA  1 
ATOM   1925 C C   . MET A 1 373 ? 124.893 158.438 115.182 1.00 218.54 ?  373  MET A C   1 
ATOM   1926 O O   . MET A 1 373 ? 125.798 159.019 114.617 1.00 218.54 ?  373  MET A O   1 
ATOM   1927 C CB  . MET A 1 373 ? 125.240 156.231 116.236 1.00 218.54 ?  373  MET A CB  1 
ATOM   1928 C CG  . MET A 1 373 ? 126.403 155.547 116.921 1.00 218.54 ?  373  MET A CG  1 
ATOM   1929 S SD  . MET A 1 373 ? 126.867 154.025 116.082 1.00 218.54 ?  373  MET A SD  1 
ATOM   1930 C CE  . MET A 1 373 ? 128.502 153.763 116.764 1.00 218.54 ?  373  MET A CE  1 
ATOM   1931 N N   . LEU A 1 374 ? 123.660 158.384 114.697 1.00 247.46 ?  374  LEU A N   1 
ATOM   1932 C CA  . LEU A 1 374 ? 123.317 159.076 113.473 1.00 247.46 ?  374  LEU A CA  1 
ATOM   1933 C C   . LEU A 1 374 ? 123.427 160.548 113.740 1.00 247.46 ?  374  LEU A C   1 
ATOM   1934 O O   . LEU A 1 374 ? 124.184 161.224 113.077 1.00 247.46 ?  374  LEU A O   1 
ATOM   1935 C CB  . LEU A 1 374 ? 121.899 158.741 113.041 1.00 247.46 ?  374  LEU A CB  1 
ATOM   1936 C CG  . LEU A 1 374 ? 121.729 157.467 112.224 1.00 247.46 ?  374  LEU A CG  1 
ATOM   1937 C CD1 . LEU A 1 374 ? 120.258 157.097 112.139 1.00 247.46 ?  374  LEU A CD1 1 
ATOM   1938 C CD2 . LEU A 1 374 ? 122.327 157.647 110.839 1.00 247.46 ?  374  LEU A CD2 1 
ATOM   1939 N N   . GLY A 1 375 ? 122.686 161.047 114.722 1.00 229.17 ?  375  GLY A N   1 
ATOM   1940 C CA  . GLY A 1 375 ? 122.720 162.457 115.075 1.00 229.17 ?  375  GLY A CA  1 
ATOM   1941 C C   . GLY A 1 375 ? 124.052 163.168 114.971 1.00 229.17 ?  375  GLY A C   1 
ATOM   1942 O O   . GLY A 1 375 ? 124.148 164.195 114.310 1.00 229.17 ?  375  GLY A O   1 
ATOM   1943 N N   . VAL A 1 376 ? 125.089 162.627 115.601 1.00 228.87 ?  376  VAL A N   1 
ATOM   1944 C CA  . VAL A 1 376 ? 126.393 163.281 115.585 1.00 228.87 ?  376  VAL A CA  1 
ATOM   1945 C C   . VAL A 1 376 ? 127.022 163.423 114.197 1.00 228.87 ?  376  VAL A C   1 
ATOM   1946 O O   . VAL A 1 376 ? 127.872 164.283 114.008 1.00 228.87 ?  376  VAL A O   1 
ATOM   1947 C CB  . VAL A 1 376 ? 127.392 162.654 116.584 1.00 228.87 ?  376  VAL A CB  1 
ATOM   1948 C CG1 . VAL A 1 376 ? 126.861 162.761 118.004 1.00 228.87 ?  376  VAL A CG1 1 
ATOM   1949 C CG2 . VAL A 1 376 ? 127.725 161.219 116.226 1.00 228.87 ?  376  VAL A CG2 1 
ATOM   1950 N N   . ARG A 1 377 ? 126.596 162.609 113.235 1.00 232.24 ?  377  ARG A N   1 
ATOM   1951 C CA  . ARG A 1 377 ? 127.125 162.703 111.873 1.00 232.24 ?  377  ARG A CA  1 
ATOM   1952 C C   . ARG A 1 377 ? 126.101 163.205 110.851 1.00 232.24 ?  377  ARG A C   1 
ATOM   1953 O O   . ARG A 1 377 ? 126.455 163.933 109.926 1.00 232.24 ?  377  ARG A O   1 
ATOM   1954 C CB  . ARG A 1 377 ? 127.746 161.370 111.429 1.00 232.24 ?  377  ARG A CB  1 
ATOM   1955 C CG  . ARG A 1 377 ? 126.770 160.222 111.243 1.00 232.24 ?  377  ARG A CG  1 
ATOM   1956 C CD  . ARG A 1 377 ? 127.423 158.893 111.576 1.00 232.24 ?  377  ARG A CD  1 
ATOM   1957 N NE  . ARG A 1 377 ? 128.500 159.048 112.549 1.00 232.24 ?  377  ARG A NE  1 
ATOM   1958 C CZ  . ARG A 1 377 ? 128.800 158.148 113.479 1.00 232.24 ?  377  ARG A CZ  1 
ATOM   1959 N NH1 . ARG A 1 377 ? 128.101 157.025 113.565 1.00 232.24 1  377  ARG A NH1 1 
ATOM   1960 N NH2 . ARG A 1 377 ? 129.797 158.370 114.323 1.00 232.24 ?  377  ARG A NH2 1 
ATOM   1961 N N   . LYS A 1 378 ? 124.839 162.830 111.015 1.00 222.40 ?  378  LYS A N   1 
ATOM   1962 C CA  . LYS A 1 378 ? 123.796 163.247 110.082 1.00 222.40 ?  378  LYS A CA  1 
ATOM   1963 C C   . LYS A 1 378 ? 123.477 164.727 110.211 1.00 222.40 ?  378  LYS A C   1 
ATOM   1964 O O   . LYS A 1 378 ? 123.107 165.365 109.226 1.00 222.40 ?  378  LYS A O   1 
ATOM   1965 C CB  . LYS A 1 378 ? 122.541 162.361 110.183 1.00 222.40 ?  378  LYS A CB  1 
ATOM   1966 C CG  . LYS A 1 378 ? 121.612 162.648 111.354 1.00 222.40 ?  378  LYS A CG  1 
ATOM   1967 C CD  . LYS A 1 378 ? 120.234 163.084 110.892 1.00 222.40 ?  378  LYS A CD  1 
ATOM   1968 C CE  . LYS A 1 378 ? 119.767 164.296 111.678 1.00 222.40 ?  378  LYS A CE  1 
ATOM   1969 N NZ  . LYS A 1 378 ? 120.544 164.456 112.936 1.00 222.40 1  378  LYS A NZ  1 
ATOM   1970 N N   . HIS A 1 379 ? 123.619 165.289 111.405 1.00 220.23 ?  379  HIS A N   1 
ATOM   1971 C CA  . HIS A 1 379 ? 123.428 166.719 111.547 1.00 220.23 ?  379  HIS A CA  1 
ATOM   1972 C C   . HIS A 1 379 ? 124.713 167.313 111.021 1.00 220.23 ?  379  HIS A C   1 
ATOM   1973 O O   . HIS A 1 379 ? 125.777 167.074 111.585 1.00 220.23 ?  379  HIS A O   1 
ATOM   1974 C CB  . HIS A 1 379 ? 123.212 167.096 113.005 1.00 220.23 ?  379  HIS A CB  1 
ATOM   1975 C CG  . HIS A 1 379 ? 122.992 168.558 113.228 1.00 220.23 ?  379  HIS A CG  1 
ATOM   1976 N ND1 . HIS A 1 379 ? 123.317 169.184 114.411 1.00 220.23 ?  379  HIS A ND1 1 
ATOM   1977 C CD2 . HIS A 1 379 ? 122.472 169.516 112.425 1.00 220.23 ?  379  HIS A CD2 1 
ATOM   1978 C CE1 . HIS A 1 379 ? 123.010 170.466 114.328 1.00 220.23 ?  379  HIS A CE1 1 
ATOM   1979 N NE2 . HIS A 1 379 ? 122.496 170.694 113.132 1.00 220.23 ?  379  HIS A NE2 1 
ATOM   1980 N N   . LYS A 1 380 ? 124.628 168.071 109.935 1.00 238.70 ?  380  LYS A N   1 
ATOM   1981 C CA  . LYS A 1 380 ? 125.832 168.615 109.320 1.00 238.70 ?  380  LYS A CA  1 
ATOM   1982 C C   . LYS A 1 380 ? 126.651 169.490 110.258 1.00 238.70 ?  380  LYS A C   1 
ATOM   1983 O O   . LYS A 1 380 ? 127.864 169.334 110.345 1.00 238.70 ?  380  LYS A O   1 
ATOM   1984 C CB  . LYS A 1 380 ? 125.494 169.377 108.040 1.00 238.70 ?  380  LYS A CB  1 
ATOM   1985 C CG  . LYS A 1 380 ? 126.438 169.081 106.884 1.00 238.70 ?  380  LYS A CG  1 
ATOM   1986 C CD  . LYS A 1 380 ? 127.128 167.735 107.049 1.00 238.70 ?  380  LYS A CD  1 
ATOM   1987 C CE  . LYS A 1 380 ? 128.621 167.837 106.773 1.00 238.70 ?  380  LYS A CE  1 
ATOM   1988 N NZ  . LYS A 1 380 ? 129.404 168.123 108.007 1.00 238.70 1  380  LYS A NZ  1 
ATOM   1989 N N   . ALA A 1 381 ? 125.992 170.400 110.966 1.00 240.43 ?  381  ALA A N   1 
ATOM   1990 C CA  . ALA A 1 381 ? 126.699 171.252 111.913 1.00 240.43 ?  381  ALA A CA  1 
ATOM   1991 C C   . ALA A 1 381 ? 127.445 170.415 112.935 1.00 240.43 ?  381  ALA A C   1 
ATOM   1992 O O   . ALA A 1 381 ? 128.619 170.660 113.196 1.00 240.43 ?  381  ALA A O   1 
ATOM   1993 C CB  . ALA A 1 381 ? 125.736 172.198 112.605 1.00 240.43 ?  381  ALA A CB  1 
ATOM   1994 N N   . LEU A 1 382 ? 126.770 169.420 113.503 1.00 228.50 ?  382  LEU A N   1 
ATOM   1995 C CA  . LEU A 1 382 ? 127.403 168.563 114.494 1.00 228.50 ?  382  LEU A CA  1 
ATOM   1996 C C   . LEU A 1 382 ? 128.656 167.907 113.951 1.00 228.50 ?  382  LEU A C   1 
ATOM   1997 O O   . LEU A 1 382 ? 129.718 168.012 114.556 1.00 228.50 ?  382  LEU A O   1 
ATOM   1998 C CB  . LEU A 1 382 ? 126.437 167.486 114.968 1.00 228.50 ?  382  LEU A CB  1 
ATOM   1999 C CG  . LEU A 1 382 ? 126.355 167.283 116.477 1.00 228.50 ?  382  LEU A CG  1 
ATOM   2000 C CD1 . LEU A 1 382 ? 126.728 168.565 117.204 1.00 228.50 ?  382  LEU A CD1 1 
ATOM   2001 C CD2 . LEU A 1 382 ? 124.964 166.819 116.876 1.00 228.50 ?  382  LEU A CD2 1 
ATOM   2002 N N   . SER A 1 383 ? 128.544 167.231 112.814 1.00 247.68 ?  383  SER A N   1 
ATOM   2003 C CA  . SER A 1 383 ? 129.693 166.518 112.274 1.00 247.68 ?  383  SER A CA  1 
ATOM   2004 C C   . SER A 1 383 ? 130.846 167.456 112.003 1.00 247.68 ?  383  SER A C   1 
ATOM   2005 O O   . SER A 1 383 ? 131.968 167.174 112.399 1.00 247.68 ?  383  SER A O   1 
ATOM   2006 C CB  . SER A 1 383 ? 129.328 165.762 111.003 1.00 247.68 ?  383  SER A CB  1 
ATOM   2007 O OG  . SER A 1 383 ? 128.246 166.376 110.337 1.00 247.68 ?  383  SER A OG  1 
ATOM   2008 N N   . GLN A 1 384 ? 130.572 168.574 111.340 1.00 260.88 ?  384  GLN A N   1 
ATOM   2009 C CA  . GLN A 1 384 ? 131.614 169.545 111.033 1.00 260.88 ?  384  GLN A CA  1 
ATOM   2010 C C   . GLN A 1 384 ? 132.325 169.989 112.302 1.00 260.88 ?  384  GLN A C   1 
ATOM   2011 O O   . GLN A 1 384 ? 133.551 169.948 112.373 1.00 260.88 ?  384  GLN A O   1 
ATOM   2012 C CB  . GLN A 1 384 ? 130.997 170.741 110.300 1.00 260.88 ?  384  GLN A CB  1 
ATOM   2013 C CG  . GLN A 1 384 ? 131.862 171.988 110.234 1.00 260.88 ?  384  GLN A CG  1 
ATOM   2014 C CD  . GLN A 1 384 ? 131.263 173.148 111.007 1.00 260.88 ?  384  GLN A CD  1 
ATOM   2015 O OE1 . GLN A 1 384 ? 131.830 174.238 111.048 1.00 260.88 ?  384  GLN A OE1 1 
ATOM   2016 N NE2 . GLN A 1 384 ? 130.112 172.917 111.628 1.00 260.88 ?  384  GLN A NE2 1 
ATOM   2017 N N   . PHE A 1 385 ? 131.561 170.389 113.312 1.00 248.33 ?  385  PHE A N   1 
ATOM   2018 C CA  . PHE A 1 385 ? 132.143 170.832 114.571 1.00 248.33 ?  385  PHE A CA  1 
ATOM   2019 C C   . PHE A 1 385 ? 133.041 169.773 115.168 1.00 248.33 ?  385  PHE A C   1 
ATOM   2020 O O   . PHE A 1 385 ? 134.187 170.045 115.511 1.00 248.33 ?  385  PHE A O   1 
ATOM   2021 C CB  . PHE A 1 385 ? 131.024 171.143 115.558 1.00 248.33 ?  385  PHE A CB  1 
ATOM   2022 C CG  . PHE A 1 385 ? 131.437 172.030 116.689 1.00 248.33 ?  385  PHE A CG  1 
ATOM   2023 C CD1 . PHE A 1 385 ? 131.653 173.379 116.481 1.00 248.33 ?  385  PHE A CD1 1 
ATOM   2024 C CD2 . PHE A 1 385 ? 131.596 171.518 117.965 1.00 248.33 ?  385  PHE A CD2 1 
ATOM   2025 C CE1 . PHE A 1 385 ? 132.027 174.203 117.523 1.00 248.33 ?  385  PHE A CE1 1 
ATOM   2026 C CE2 . PHE A 1 385 ? 131.971 172.335 119.011 1.00 248.33 ?  385  PHE A CE2 1 
ATOM   2027 C CZ  . PHE A 1 385 ? 132.187 173.681 118.791 1.00 248.33 ?  385  PHE A CZ  1 
ATOM   2028 N N   . LEU A 1 386 ? 132.536 168.554 115.278 1.00 263.65 ?  386  LEU A N   1 
ATOM   2029 C CA  . LEU A 1 386 ? 133.299 167.490 115.916 1.00 263.65 ?  386  LEU A CA  1 
ATOM   2030 C C   . LEU A 1 386 ? 134.443 166.953 115.065 1.00 263.65 ?  386  LEU A C   1 
ATOM   2031 O O   . LEU A 1 386 ? 135.262 166.182 115.549 1.00 263.65 ?  386  LEU A O   1 
ATOM   2032 C CB  . LEU A 1 386 ? 132.365 166.346 116.306 1.00 263.65 ?  386  LEU A CB  1 
ATOM   2033 C CG  . LEU A 1 386 ? 131.625 166.383 117.646 1.00 263.65 ?  386  LEU A CG  1 
ATOM   2034 C CD1 . LEU A 1 386 ? 131.839 167.664 118.439 1.00 263.65 ?  386  LEU A CD1 1 
ATOM   2035 C CD2 . LEU A 1 386 ? 130.145 166.084 117.470 1.00 263.65 ?  386  LEU A CD2 1 
ATOM   2036 N N   . ALA A 1 387 ? 134.501 167.333 113.796 1.00 306.87 ?  387  ALA A N   1 
ATOM   2037 C CA  . ALA A 1 387 ? 135.614 166.913 112.960 1.00 306.87 ?  387  ALA A CA  1 
ATOM   2038 C C   . ALA A 1 387 ? 136.720 167.930 113.103 1.00 306.87 ?  387  ALA A C   1 
ATOM   2039 O O   . ALA A 1 387 ? 137.898 167.590 113.015 1.00 306.87 ?  387  ALA A O   1 
ATOM   2040 C CB  . ALA A 1 387 ? 135.187 166.789 111.510 1.00 306.87 ?  387  ALA A CB  1 
ATOM   2041 N N   . LYS A 1 388 ? 136.348 169.185 113.323 1.00 268.22 ?  388  LYS A N   1 
ATOM   2042 C CA  . LYS A 1 388 ? 137.349 170.213 113.537 1.00 268.22 ?  388  LYS A CA  1 
ATOM   2043 C C   . LYS A 1 388 ? 137.971 169.972 114.892 1.00 268.22 ?  388  LYS A C   1 
ATOM   2044 O O   . LYS A 1 388 ? 139.193 169.923 115.021 1.00 268.22 ?  388  LYS A O   1 
ATOM   2045 C CB  . LYS A 1 388 ? 136.710 171.595 113.487 1.00 268.22 ?  388  LYS A CB  1 
ATOM   2046 C CG  . LYS A 1 388 ? 136.352 172.052 112.085 1.00 268.22 ?  388  LYS A CG  1 
ATOM   2047 C CD  . LYS A 1 388 ? 135.218 173.063 112.110 1.00 268.22 ?  388  LYS A CD  1 
ATOM   2048 C CE  . LYS A 1 388 ? 134.822 173.399 113.536 1.00 268.22 ?  388  LYS A CE  1 
ATOM   2049 N NZ  . LYS A 1 388 ? 133.540 174.149 113.606 1.00 268.22 1  388  LYS A NZ  1 
ATOM   2050 N N   . HIS A 1 389 ? 137.136 169.816 115.909 1.00 274.50 ?  389  HIS A N   1 
ATOM   2051 C CA  . HIS A 1 389 ? 137.645 169.511 117.235 1.00 274.50 ?  389  HIS A CA  1 
ATOM   2052 C C   . HIS A 1 389 ? 137.341 168.061 117.530 1.00 274.50 ?  389  HIS A C   1 
ATOM   2053 O O   . HIS A 1 389 ? 136.262 167.739 118.013 1.00 274.50 ?  389  HIS A O   1 
ATOM   2054 C CB  . HIS A 1 389 ? 136.998 170.411 118.275 1.00 274.50 ?  389  HIS A CB  1 
ATOM   2055 C CG  . HIS A 1 389 ? 136.542 171.727 117.730 1.00 274.50 ?  389  HIS A CG  1 
ATOM   2056 N ND1 . HIS A 1 389 ? 137.417 172.689 117.276 1.00 274.50 ?  389  HIS A ND1 1 
ATOM   2057 C CD2 . HIS A 1 389 ? 135.300 172.240 117.565 1.00 274.50 ?  389  HIS A CD2 1 
ATOM   2058 C CE1 . HIS A 1 389 ? 136.734 173.738 116.854 1.00 274.50 ?  389  HIS A CE1 1 
ATOM   2059 N NE2 . HIS A 1 389 ? 135.447 173.490 117.019 1.00 274.50 ?  389  HIS A NE2 1 
ATOM   2060 N N   . ARG A 1 390 ? 138.289 167.182 117.240 1.00 261.05 ?  390  ARG A N   1 
ATOM   2061 C CA  . ARG A 1 390 ? 138.067 165.753 117.431 1.00 261.05 ?  390  ARG A CA  1 
ATOM   2062 C C   . ARG A 1 390 ? 137.807 165.360 118.871 1.00 261.05 ?  390  ARG A C   1 
ATOM   2063 O O   . ARG A 1 390 ? 136.927 164.548 119.134 1.00 261.05 ?  390  ARG A O   1 
ATOM   2064 C CB  . ARG A 1 390 ? 139.263 164.963 116.904 1.00 261.05 ?  390  ARG A CB  1 
ATOM   2065 C CG  . ARG A 1 390 ? 139.533 165.177 115.429 1.00 261.05 ?  390  ARG A CG  1 
ATOM   2066 C CD  . ARG A 1 390 ? 138.636 164.291 114.589 1.00 261.05 ?  390  ARG A CD  1 
ATOM   2067 N NE  . ARG A 1 390 ? 138.853 164.504 113.165 1.00 261.05 ?  390  ARG A NE  1 
ATOM   2068 C CZ  . ARG A 1 390 ? 138.032 164.072 112.216 1.00 261.05 ?  390  ARG A CZ  1 
ATOM   2069 N NH1 . ARG A 1 390 ? 136.933 163.407 112.543 1.00 261.05 1  390  ARG A NH1 1 
ATOM   2070 N NH2 . ARG A 1 390 ? 138.304 164.311 110.941 1.00 261.05 ?  390  ARG A NH2 1 
ATOM   2071 N N   . LEU A 1 391 ? 138.553 165.935 119.807 1.00 317.49 ?  391  LEU A N   1 
ATOM   2072 C CA  . LEU A 1 391 ? 138.419 165.550 121.209 1.00 317.49 ?  391  LEU A CA  1 
ATOM   2073 C C   . LEU A 1 391 ? 137.316 166.282 121.960 1.00 317.49 ?  391  LEU A C   1 
ATOM   2074 O O   . LEU A 1 391 ? 137.246 166.205 123.181 1.00 317.49 ?  391  LEU A O   1 
ATOM   2075 C CB  . LEU A 1 391 ? 139.751 165.734 121.934 1.00 317.49 ?  391  LEU A CB  1 
ATOM   2076 C CG  . LEU A 1 391 ? 140.933 164.907 121.428 1.00 317.49 ?  391  LEU A CG  1 
ATOM   2077 C CD1 . LEU A 1 391 ? 142.163 165.167 122.280 1.00 317.49 ?  391  LEU A CD1 1 
ATOM   2078 C CD2 . LEU A 1 391 ? 140.597 163.427 121.419 1.00 317.49 ?  391  LEU A CD2 1 
ATOM   2079 N N   . LEU A 1 392 ? 136.452 166.985 121.239 1.00 322.38 ?  392  LEU A N   1 
ATOM   2080 C CA  . LEU A 1 392 ? 135.344 167.678 121.876 1.00 322.38 ?  392  LEU A CA  1 
ATOM   2081 C C   . LEU A 1 392 ? 134.318 166.674 122.355 1.00 322.38 ?  392  LEU A C   1 
ATOM   2082 O O   . LEU A 1 392 ? 134.044 166.598 123.540 1.00 322.38 ?  392  LEU A O   1 
ATOM   2083 C CB  . LEU A 1 392 ? 134.690 168.659 120.910 1.00 322.38 ?  392  LEU A CB  1 
ATOM   2084 C CG  . LEU A 1 392 ? 134.571 170.109 121.372 1.00 322.38 ?  392  LEU A CG  1 
ATOM   2085 C CD1 . LEU A 1 392 ? 133.242 170.342 122.070 1.00 322.38 ?  392  LEU A CD1 1 
ATOM   2086 C CD2 . LEU A 1 392 ? 135.731 170.471 122.283 1.00 322.38 ?  392  LEU A CD2 1 
ATOM   2087 N N   . TYR A 1 393 ? 133.755 165.902 121.434 1.00 284.68 ?  393  TYR A N   1 
ATOM   2088 C CA  . TYR A 1 393 ? 132.755 164.903 121.803 1.00 284.68 ?  393  TYR A CA  1 
ATOM   2089 C C   . TYR A 1 393 ? 133.173 163.970 122.938 1.00 284.68 ?  393  TYR A C   1 
ATOM   2090 O O   . TYR A 1 393 ? 132.478 163.906 123.944 1.00 284.68 ?  393  TYR A O   1 
ATOM   2091 C CB  . TYR A 1 393 ? 132.229 164.121 120.587 1.00 284.68 ?  393  TYR A CB  1 
ATOM   2092 C CG  . TYR A 1 393 ? 131.022 163.264 120.885 1.00 284.68 ?  393  TYR A CG  1 
ATOM   2093 C CD1 . TYR A 1 393 ? 129.784 163.839 121.119 1.00 284.68 ?  393  TYR A CD1 1 
ATOM   2094 C CD2 . TYR A 1 393 ? 131.121 161.880 120.931 1.00 284.68 ?  393  TYR A CD2 1 
ATOM   2095 C CE1 . TYR A 1 393 ? 128.677 163.061 121.391 1.00 284.68 ?  393  TYR A CE1 1 
ATOM   2096 C CE2 . TYR A 1 393 ? 130.019 161.094 121.205 1.00 284.68 ?  393  TYR A CE2 1 
ATOM   2097 C CZ  . TYR A 1 393 ? 128.800 161.689 121.432 1.00 284.68 ?  393  TYR A CZ  1 
ATOM   2098 O OH  . TYR A 1 393 ? 127.699 160.914 121.707 1.00 284.68 ?  393  TYR A OH  1 
ATOM   2099 N N   . PRO A 1 394 ? 134.306 163.245 122.798 1.00 278.97 ?  394  PRO A N   1 
ATOM   2100 C CA  . PRO A 1 394 ? 134.610 162.382 123.943 1.00 278.97 ?  394  PRO A CA  1 
ATOM   2101 C C   . PRO A 1 394 ? 134.784 163.175 125.222 1.00 278.97 ?  394  PRO A C   1 
ATOM   2102 O O   . PRO A 1 394 ? 134.263 162.760 126.242 1.00 278.97 ?  394  PRO A O   1 
ATOM   2103 C CB  . PRO A 1 394 ? 135.918 161.688 123.540 1.00 278.97 ?  394  PRO A CB  1 
ATOM   2104 C CG  . PRO A 1 394 ? 136.476 162.488 122.425 1.00 278.97 ?  394  PRO A CG  1 
ATOM   2105 C CD  . PRO A 1 394 ? 135.297 163.070 121.719 1.00 278.97 ?  394  PRO A CD  1 
ATOM   2106 N N   . GLY A 1 395 ? 135.469 164.309 125.166 1.00 324.54 ?  395  GLY A N   1 
ATOM   2107 C CA  . GLY A 1 395 ? 135.667 165.141 126.332 1.00 324.54 ?  395  GLY A CA  1 
ATOM   2108 C C   . GLY A 1 395 ? 134.395 165.530 127.041 1.00 324.54 ?  395  GLY A C   1 
ATOM   2109 O O   . GLY A 1 395 ? 134.251 165.276 128.229 1.00 324.54 ?  395  GLY A O   1 
ATOM   2110 N N   . ILE A 1 396 ? 133.463 166.139 126.323 1.00 365.59 ?  396  ILE A N   1 
ATOM   2111 C CA  . ILE A 1 396 ? 132.241 166.596 126.958 1.00 365.59 ?  396  ILE A CA  1 
ATOM   2112 C C   . ILE A 1 396 ? 131.405 165.440 127.492 1.00 365.59 ?  396  ILE A C   1 
ATOM   2113 O O   . ILE A 1 396 ? 130.845 165.542 128.572 1.00 365.59 ?  396  ILE A O   1 
ATOM   2114 C CB  . ILE A 1 396 ? 131.412 167.550 126.062 1.00 365.59 ?  396  ILE A CB  1 
ATOM   2115 C CG1 . ILE A 1 396 ? 130.888 166.850 124.805 1.00 365.59 ?  396  ILE A CG1 1 
ATOM   2116 C CG2 . ILE A 1 396 ? 132.238 168.767 125.683 1.00 365.59 ?  396  ILE A CG2 1 
ATOM   2117 C CD1 . ILE A 1 396 ? 130.512 167.791 123.685 1.00 365.59 ?  396  ILE A CD1 1 
ATOM   2118 N N   . VAL A 1 397 ? 131.352 164.329 126.766 1.00 328.67 ?  397  VAL A N   1 
ATOM   2119 C CA  . VAL A 1 397 ? 130.581 163.183 127.210 1.00 328.67 ?  397  VAL A CA  1 
ATOM   2120 C C   . VAL A 1 397 ? 131.182 162.637 128.495 1.00 328.67 ?  397  VAL A C   1 
ATOM   2121 O O   . VAL A 1 397 ? 130.482 162.471 129.483 1.00 328.67 ?  397  VAL A O   1 
ATOM   2122 C CB  . VAL A 1 397 ? 130.479 162.104 126.114 1.00 328.67 ?  397  VAL A CB  1 
ATOM   2123 C CG1 . VAL A 1 397 ? 130.009 160.782 126.686 1.00 328.67 ?  397  VAL A CG1 1 
ATOM   2124 C CG2 . VAL A 1 397 ? 129.521 162.560 125.032 1.00 328.67 ?  397  VAL A CG2 1 
ATOM   2125 N N   . THR A 1 398 ? 132.488 162.410 128.505 1.00 299.27 ?  398  THR A N   1 
ATOM   2126 C CA  . THR A 1 398 ? 133.150 161.929 129.706 1.00 299.27 ?  398  THR A CA  1 
ATOM   2127 C C   . THR A 1 398 ? 132.912 162.857 130.876 1.00 299.27 ?  398  THR A C   1 
ATOM   2128 O O   . THR A 1 398 ? 132.529 162.410 131.950 1.00 299.27 ?  398  THR A O   1 
ATOM   2129 C CB  . THR A 1 398 ? 134.653 161.791 129.485 1.00 299.27 ?  398  THR A CB  1 
ATOM   2130 O OG1 . THR A 1 398 ? 134.878 161.047 128.288 1.00 299.27 ?  398  THR A OG1 1 
ATOM   2131 C CG2 . THR A 1 398 ? 135.280 161.062 130.626 1.00 299.27 ?  398  THR A CG2 1 
ATOM   2132 N N   . PHE A 1 399 ? 133.118 164.151 130.669 1.00 309.78 ?  399  PHE A N   1 
ATOM   2133 C CA  . PHE A 1 399 ? 132.900 165.114 131.731 1.00 309.78 ?  399  PHE A CA  1 
ATOM   2134 C C   . PHE A 1 399 ? 131.505 165.000 132.318 1.00 309.78 ?  399  PHE A C   1 
ATOM   2135 O O   . PHE A 1 399 ? 131.368 164.876 133.522 1.00 309.78 ?  399  PHE A O   1 
ATOM   2136 C CB  . PHE A 1 399 ? 133.151 166.542 131.254 1.00 309.78 ?  399  PHE A CB  1 
ATOM   2137 C CG  . PHE A 1 399 ? 132.917 167.576 132.314 1.00 309.78 ?  399  PHE A CG  1 
ATOM   2138 C CD1 . PHE A 1 399 ? 133.782 167.687 133.387 1.00 309.78 ?  399  PHE A CD1 1 
ATOM   2139 C CD2 . PHE A 1 399 ? 131.824 168.422 132.250 1.00 309.78 ?  399  PHE A CD2 1 
ATOM   2140 C CE1 . PHE A 1 399 ? 133.566 168.627 134.373 1.00 309.78 ?  399  PHE A CE1 1 
ATOM   2141 C CE2 . PHE A 1 399 ? 131.600 169.362 133.235 1.00 309.78 ?  399  PHE A CE2 1 
ATOM   2142 C CZ  . PHE A 1 399 ? 132.475 169.466 134.297 1.00 309.78 ?  399  PHE A CZ  1 
ATOM   2143 N N   . VAL A 1 400 ? 130.469 165.041 131.486 1.00 287.95 ?  400  VAL A N   1 
ATOM   2144 C CA  . VAL A 1 400 ? 129.115 165.014 132.025 1.00 287.95 ?  400  VAL A CA  1 
ATOM   2145 C C   . VAL A 1 400 ? 128.755 163.692 132.695 1.00 287.95 ?  400  VAL A C   1 
ATOM   2146 O O   . VAL A 1 400 ? 128.052 163.691 133.696 1.00 287.95 ?  400  VAL A O   1 
ATOM   2147 C CB  . VAL A 1 400 ? 128.030 165.474 131.017 1.00 287.95 ?  400  VAL A CB  1 
ATOM   2148 C CG1 . VAL A 1 400 ? 128.357 166.855 130.476 1.00 287.95 ?  400  VAL A CG1 1 
ATOM   2149 C CG2 . VAL A 1 400 ? 127.808 164.475 129.895 1.00 287.95 ?  400  VAL A CG2 1 
ATOM   2150 N N   . ILE A 1 401 ? 129.258 162.573 132.184 1.00 229.00 ?  401  ILE A N   1 
ATOM   2151 C CA  . ILE A 1 401 ? 129.008 161.294 132.828 1.00 229.00 ?  401  ILE A CA  1 
ATOM   2152 C C   . ILE A 1 401 ? 129.650 161.326 134.201 1.00 229.00 ?  401  ILE A C   1 
ATOM   2153 O O   . ILE A 1 401 ? 129.005 161.022 135.196 1.00 229.00 ?  401  ILE A O   1 
ATOM   2154 C CB  . ILE A 1 401 ? 129.563 160.115 131.999 1.00 229.00 ?  401  ILE A CB  1 
ATOM   2155 C CG1 . ILE A 1 401 ? 128.763 159.944 130.713 1.00 229.00 ?  401  ILE A CG1 1 
ATOM   2156 C CG2 . ILE A 1 401 ? 129.536 158.817 132.789 1.00 229.00 ?  401  ILE A CG2 1 
ATOM   2157 C CD1 . ILE A 1 401 ? 129.243 158.787 129.871 1.00 229.00 ?  401  ILE A CD1 1 
ATOM   2158 N N   . ALA A 1 402 ? 130.908 161.744 134.268 1.00 255.59 ?  402  ALA A N   1 
ATOM   2159 C CA  . ALA A 1 402 ? 131.619 161.765 135.534 1.00 255.59 ?  402  ALA A CA  1 
ATOM   2160 C C   . ALA A 1 402 ? 131.091 162.805 136.511 1.00 255.59 ?  402  ALA A C   1 
ATOM   2161 O O   . ALA A 1 402 ? 131.191 162.629 137.715 1.00 255.59 ?  402  ALA A O   1 
ATOM   2162 C CB  . ALA A 1 402 ? 133.101 161.946 135.297 1.00 255.59 ?  402  ALA A CB  1 
ATOM   2163 N N   . SER A 1 403 ? 130.507 163.879 136.006 1.00 271.02 ?  403  SER A N   1 
ATOM   2164 C CA  . SER A 1 403 ? 129.952 164.903 136.873 1.00 271.02 ?  403  SER A CA  1 
ATOM   2165 C C   . SER A 1 403 ? 128.639 164.440 137.469 1.00 271.02 ?  403  SER A C   1 
ATOM   2166 O O   . SER A 1 403 ? 128.253 164.879 138.549 1.00 271.02 ?  403  SER A O   1 
ATOM   2167 C CB  . SER A 1 403 ? 129.755 166.204 136.101 1.00 271.02 ?  403  SER A CB  1 
ATOM   2168 O OG  . SER A 1 403 ? 128.564 166.168 135.339 1.00 271.02 ?  403  SER A OG  1 
ATOM   2169 N N   . PHE A 1 404 ? 127.945 163.550 136.773 1.00 221.39 ?  404  PHE A N   1 
ATOM   2170 C CA  . PHE A 1 404 ? 126.697 163.016 137.288 1.00 221.39 ?  404  PHE A CA  1 
ATOM   2171 C C   . PHE A 1 404 ? 126.971 161.829 138.189 1.00 221.39 ?  404  PHE A C   1 
ATOM   2172 O O   . PHE A 1 404 ? 126.175 161.516 139.063 1.00 221.39 ?  404  PHE A O   1 
ATOM   2173 C CB  . PHE A 1 404 ? 125.802 162.586 136.142 1.00 221.39 ?  404  PHE A CB  1 
ATOM   2174 C CG  . PHE A 1 404 ? 124.792 163.610 135.738 1.00 221.39 ?  404  PHE A CG  1 
ATOM   2175 C CD1 . PHE A 1 404 ? 123.559 163.658 136.354 1.00 221.39 ?  404  PHE A CD1 1 
ATOM   2176 C CD2 . PHE A 1 404 ? 125.069 164.513 134.730 1.00 221.39 ?  404  PHE A CD2 1 
ATOM   2177 C CE1 . PHE A 1 404 ? 122.620 164.598 135.981 1.00 221.39 ?  404  PHE A CE1 1 
ATOM   2178 C CE2 . PHE A 1 404 ? 124.139 165.454 134.348 1.00 221.39 ?  404  PHE A CE2 1 
ATOM   2179 C CZ  . PHE A 1 404 ? 122.910 165.497 134.975 1.00 221.39 ?  404  PHE A CZ  1 
ATOM   2180 N N   . THR A 1 405 ? 128.099 161.158 137.984 1.00 183.45 ?  405  THR A N   1 
ATOM   2181 C CA  . THR A 1 405 ? 128.456 160.044 138.846 1.00 183.45 ?  405  THR A CA  1 
ATOM   2182 C C   . THR A 1 405 ? 129.341 160.495 139.977 1.00 183.45 ?  405  THR A C   1 
ATOM   2183 O O   . THR A 1 405 ? 129.876 159.658 140.686 1.00 183.45 ?  405  THR A O   1 
ATOM   2184 C CB  . THR A 1 405 ? 129.189 158.914 138.102 1.00 183.45 ?  405  THR A CB  1 
ATOM   2185 O OG1 . THR A 1 405 ? 130.377 159.424 137.490 1.00 183.45 ?  405  THR A OG1 1 
ATOM   2186 C CG2 . THR A 1 405 ? 128.306 158.283 137.060 1.00 183.45 ?  405  THR A CG2 1 
ATOM   2187 N N   . PHE A 1 406 ? 129.519 161.801 140.139 1.00 174.21 ?  406  PHE A N   1 
ATOM   2188 C CA  . PHE A 1 406 ? 130.298 162.330 141.249 1.00 174.21 ?  406  PHE A CA  1 
ATOM   2189 C C   . PHE A 1 406 ? 129.603 161.913 142.522 1.00 174.21 ?  406  PHE A C   1 
ATOM   2190 O O   . PHE A 1 406 ? 128.476 162.324 142.760 1.00 174.21 ?  406  PHE A O   1 
ATOM   2191 C CB  . PHE A 1 406 ? 130.386 163.850 141.148 1.00 174.21 ?  406  PHE A CB  1 
ATOM   2192 C CG  . PHE A 1 406 ? 131.244 164.485 142.201 1.00 174.21 ?  406  PHE A CG  1 
ATOM   2193 C CD1 . PHE A 1 406 ? 132.501 163.989 142.483 1.00 174.21 ?  406  PHE A CD1 1 
ATOM   2194 C CD2 . PHE A 1 406 ? 130.792 165.589 142.901 1.00 174.21 ?  406  PHE A CD2 1 
ATOM   2195 C CE1 . PHE A 1 406 ? 133.284 164.566 143.458 1.00 174.21 ?  406  PHE A CE1 1 
ATOM   2196 C CE2 . PHE A 1 406 ? 131.577 166.182 143.867 1.00 174.21 ?  406  PHE A CE2 1 
ATOM   2197 C CZ  . PHE A 1 406 ? 132.826 165.670 144.147 1.00 174.21 ?  406  PHE A CZ  1 
ATOM   2198 N N   . PRO A 1 407 ? 130.273 161.102 143.356 1.00 178.86 ?  407  PRO A N   1 
ATOM   2199 C CA  . PRO A 1 407 ? 129.597 160.570 144.546 1.00 178.86 ?  407  PRO A CA  1 
ATOM   2200 C C   . PRO A 1 407 ? 128.885 161.547 145.498 1.00 178.86 ?  407  PRO A C   1 
ATOM   2201 O O   . PRO A 1 407 ? 127.816 161.191 145.960 1.00 178.86 ?  407  PRO A O   1 
ATOM   2202 C CB  . PRO A 1 407 ? 130.687 159.729 145.227 1.00 178.86 ?  407  PRO A CB  1 
ATOM   2203 C CG  . PRO A 1 407 ? 131.637 159.396 144.131 1.00 178.86 ?  407  PRO A CG  1 
ATOM   2204 C CD  . PRO A 1 407 ? 131.652 160.602 143.248 1.00 178.86 ?  407  PRO A CD  1 
ATOM   2205 N N   . PRO A 1 408 ? 129.447 162.737 145.804 1.00 194.77 ?  408  PRO A N   1 
ATOM   2206 C CA  . PRO A 1 408 ? 128.659 163.638 146.655 1.00 194.77 ?  408  PRO A CA  1 
ATOM   2207 C C   . PRO A 1 408 ? 127.653 164.495 145.895 1.00 194.77 ?  408  PRO A C   1 
ATOM   2208 O O   . PRO A 1 408 ? 126.881 165.203 146.530 1.00 194.77 ?  408  PRO A O   1 
ATOM   2209 C CB  . PRO A 1 408 ? 129.724 164.545 147.277 1.00 194.77 ?  408  PRO A CB  1 
ATOM   2210 C CG  . PRO A 1 408 ? 130.990 163.783 147.164 1.00 194.77 ?  408  PRO A CG  1 
ATOM   2211 C CD  . PRO A 1 408 ? 130.858 163.142 145.827 1.00 194.77 ?  408  PRO A CD  1 
ATOM   2212 N N   . GLY A 1 409 ? 127.664 164.443 144.570 1.00 199.57 ?  409  GLY A N   1 
ATOM   2213 C CA  . GLY A 1 409 ? 126.752 165.241 143.779 1.00 199.57 ?  409  GLY A CA  1 
ATOM   2214 C C   . GLY A 1 409 ? 125.466 164.512 143.475 1.00 199.57 ?  409  GLY A C   1 
ATOM   2215 O O   . GLY A 1 409 ? 124.522 164.556 144.254 1.00 199.57 ?  409  GLY A O   1 
ATOM   2216 N N   . MET A 1 410 ? 125.414 163.842 142.334 1.00 185.66 ?  410  MET A N   1 
ATOM   2217 C CA  . MET A 1 410 ? 124.231 163.075 141.983 1.00 185.66 ?  410  MET A CA  1 
ATOM   2218 C C   . MET A 1 410 ? 124.525 161.601 142.152 1.00 185.66 ?  410  MET A C   1 
ATOM   2219 O O   . MET A 1 410 ? 123.611 160.791 142.214 1.00 185.66 ?  410  MET A O   1 
ATOM   2220 C CB  . MET A 1 410 ? 123.798 163.380 140.551 1.00 185.66 ?  410  MET A CB  1 
ATOM   2221 C CG  . MET A 1 410 ? 122.298 163.319 140.325 1.00 185.66 ?  410  MET A CG  1 
ATOM   2222 S SD  . MET A 1 410 ? 121.822 161.914 139.302 1.00 185.66 ?  410  MET A SD  1 
ATOM   2223 C CE  . MET A 1 410 ? 120.540 161.168 140.302 1.00 185.66 ?  410  MET A CE  1 
ATOM   2224 N N   . GLY A 1 411 ? 125.798 161.249 142.281 1.00 195.24 ?  411  GLY A N   1 
ATOM   2225 C CA  . GLY A 1 411 ? 126.186 159.860 142.437 1.00 195.24 ?  411  GLY A CA  1 
ATOM   2226 C C   . GLY A 1 411 ? 125.890 159.241 143.782 1.00 195.24 ?  411  GLY A C   1 
ATOM   2227 O O   . GLY A 1 411 ? 126.346 158.139 144.064 1.00 195.24 ?  411  GLY A O   1 
ATOM   2228 N N   . GLN A 1 412 ? 125.147 159.938 144.630 1.00 219.13 ?  412  GLN A N   1 
ATOM   2229 C CA  . GLN A 1 412 ? 124.753 159.377 145.903 1.00 219.13 ?  412  GLN A CA  1 
ATOM   2230 C C   . GLN A 1 412 ? 123.378 158.794 145.718 1.00 219.13 ?  412  GLN A C   1 
ATOM   2231 O O   . GLN A 1 412 ? 122.928 157.976 146.513 1.00 219.13 ?  412  GLN A O   1 
ATOM   2232 C CB  . GLN A 1 412 ? 124.708 160.466 146.957 1.00 219.13 ?  412  GLN A CB  1 
ATOM   2233 C CG  . GLN A 1 412 ? 124.457 161.853 146.403 1.00 219.13 ?  412  GLN A CG  1 
ATOM   2234 C CD  . GLN A 1 412 ? 124.270 162.874 147.500 1.00 219.13 ?  412  GLN A CD  1 
ATOM   2235 O OE1 . GLN A 1 412 ? 124.219 162.529 148.678 1.00 219.13 ?  412  GLN A OE1 1 
ATOM   2236 N NE2 . GLN A 1 412 ? 124.167 164.139 147.122 1.00 219.13 ?  412  GLN A NE2 1 
ATOM   2237 N N   . PHE A 1 413 ? 122.703 159.208 144.654 1.00 216.77 ?  413  PHE A N   1 
ATOM   2238 C CA  . PHE A 1 413 ? 121.368 158.714 144.387 1.00 216.77 ?  413  PHE A CA  1 
ATOM   2239 C C   . PHE A 1 413 ? 121.391 157.703 143.263 1.00 216.77 ?  413  PHE A C   1 
ATOM   2240 O O   . PHE A 1 413 ? 120.345 157.257 142.821 1.00 216.77 ?  413  PHE A O   1 
ATOM   2241 C CB  . PHE A 1 413 ? 120.437 159.857 143.994 1.00 216.77 ?  413  PHE A CB  1 
ATOM   2242 C CG  . PHE A 1 413 ? 120.573 161.077 144.849 1.00 216.77 ?  413  PHE A CG  1 
ATOM   2243 C CD1 . PHE A 1 413 ? 120.300 161.026 146.204 1.00 216.77 ?  413  PHE A CD1 1 
ATOM   2244 C CD2 . PHE A 1 413 ? 120.959 162.283 144.293 1.00 216.77 ?  413  PHE A CD2 1 
ATOM   2245 C CE1 . PHE A 1 413 ? 120.421 162.151 146.989 1.00 216.77 ?  413  PHE A CE1 1 
ATOM   2246 C CE2 . PHE A 1 413 ? 121.080 163.414 145.074 1.00 216.77 ?  413  PHE A CE2 1 
ATOM   2247 C CZ  . PHE A 1 413 ? 120.806 163.347 146.424 1.00 216.77 ?  413  PHE A CZ  1 
ATOM   2248 N N   . MET A 1 414 ? 122.576 157.351 142.790 1.00 192.46 ?  414  MET A N   1 
ATOM   2249 C CA  . MET A 1 414 ? 122.689 156.405 141.696 1.00 192.46 ?  414  MET A CA  1 
ATOM   2250 C C   . MET A 1 414 ? 123.929 155.547 141.843 1.00 192.46 ?  414  MET A C   1 
ATOM   2251 O O   . MET A 1 414 ? 124.357 154.943 140.876 1.00 192.46 ?  414  MET A O   1 
ATOM   2252 C CB  . MET A 1 414 ? 122.721 157.133 140.350 1.00 192.46 ?  414  MET A CB  1 
ATOM   2253 C CG  . MET A 1 414 ? 123.812 158.181 140.233 1.00 192.46 ?  414  MET A CG  1 
ATOM   2254 S SD  . MET A 1 414 ? 124.520 158.396 138.592 1.00 192.46 ?  414  MET A SD  1 
ATOM   2255 C CE  . MET A 1 414 ? 124.781 156.703 138.074 1.00 192.46 ?  414  MET A CE  1 
ATOM   2256 N N   . ALA A 1 415 ? 124.506 155.490 143.039 1.00 185.24 ?  415  ALA A N   1 
ATOM   2257 C CA  . ALA A 1 415 ? 125.737 154.726 143.272 1.00 185.24 ?  415  ALA A CA  1 
ATOM   2258 C C   . ALA A 1 415 ? 126.788 154.977 142.208 1.00 185.24 ?  415  ALA A C   1 
ATOM   2259 O O   . ALA A 1 415 ? 127.240 154.047 141.548 1.00 185.24 ?  415  ALA A O   1 
ATOM   2260 C CB  . ALA A 1 415 ? 125.454 153.237 143.415 1.00 185.24 ?  415  ALA A CB  1 
ATOM   2261 N N   . GLY A 1 416 ? 127.193 156.231 142.049 1.00 188.90 ?  416  GLY A N   1 
ATOM   2262 C CA  . GLY A 1 416 ? 128.191 156.578 141.056 1.00 188.90 ?  416  GLY A CA  1 
ATOM   2263 C C   . GLY A 1 416 ? 129.579 156.216 141.512 1.00 188.90 ?  416  GLY A C   1 
ATOM   2264 O O   . GLY A 1 416 ? 130.479 156.098 140.691 1.00 188.90 ?  416  GLY A O   1 
ATOM   2265 N N   . GLU A 1 417 ? 129.747 156.014 142.814 1.00 190.96 ?  417  GLU A N   1 
ATOM   2266 C CA  . GLU A 1 417 ? 131.033 155.602 143.366 1.00 190.96 ?  417  GLU A CA  1 
ATOM   2267 C C   . GLU A 1 417 ? 131.398 154.260 142.784 1.00 190.96 ?  417  GLU A C   1 
ATOM   2268 O O   . GLU A 1 417 ? 132.565 153.988 142.503 1.00 190.96 ?  417  GLU A O   1 
ATOM   2269 C CB  . GLU A 1 417 ? 130.910 155.496 144.891 1.00 190.96 ?  417  GLU A CB  1 
ATOM   2270 C CG  . GLU A 1 417 ? 132.058 154.784 145.596 1.00 190.96 ?  417  GLU A CG  1 
ATOM   2271 C CD  . GLU A 1 417 ? 131.583 153.886 146.722 1.00 190.96 ?  417  GLU A CD  1 
ATOM   2272 O OE1 . GLU A 1 417 ? 132.429 153.384 147.489 1.00 190.96 ?  417  GLU A OE1 1 
ATOM   2273 O OE2 . GLU A 1 417 ? 130.357 153.680 146.846 1.00 190.96 -1 417  GLU A OE2 1 
ATOM   2274 N N   . LEU A 1 418 ? 130.396 153.421 142.570 1.00 187.00 ?  418  LEU A N   1 
ATOM   2275 C CA  . LEU A 1 418 ? 130.632 152.094 142.042 1.00 187.00 ?  418  LEU A CA  1 
ATOM   2276 C C   . LEU A 1 418 ? 131.039 152.113 140.591 1.00 187.00 ?  418  LEU A C   1 
ATOM   2277 O O   . LEU A 1 418 ? 130.405 152.764 139.770 1.00 187.00 ?  418  LEU A O   1 
ATOM   2278 C CB  . LEU A 1 418 ? 129.395 151.229 142.221 1.00 187.00 ?  418  LEU A CB  1 
ATOM   2279 C CG  . LEU A 1 418 ? 129.216 150.687 143.631 1.00 187.00 ?  418  LEU A CG  1 
ATOM   2280 C CD1 . LEU A 1 418 ? 128.426 149.402 143.589 1.00 187.00 ?  418  LEU A CD1 1 
ATOM   2281 C CD2 . LEU A 1 418 ? 130.533 150.481 144.358 1.00 187.00 ?  418  LEU A CD2 1 
ATOM   2282 N N   . MET A 1 419 ? 132.101 151.390 140.273 1.00 204.53 ?  419  MET A N   1 
ATOM   2283 C CA  . MET A 1 419 ? 132.560 151.305 138.903 1.00 204.53 ?  419  MET A CA  1 
ATOM   2284 C C   . MET A 1 419 ? 131.881 150.089 138.302 1.00 204.53 ?  419  MET A C   1 
ATOM   2285 O O   . MET A 1 419 ? 131.380 149.264 139.046 1.00 204.53 ?  419  MET A O   1 
ATOM   2286 C CB  . MET A 1 419 ? 134.085 151.195 138.893 1.00 204.53 ?  419  MET A CB  1 
ATOM   2287 C CG  . MET A 1 419 ? 134.775 152.497 138.510 1.00 204.53 ?  419  MET A CG  1 
ATOM   2288 S SD  . MET A 1 419 ? 134.304 153.928 139.502 1.00 204.53 ?  419  MET A SD  1 
ATOM   2289 C CE  . MET A 1 419 ? 133.485 154.968 138.296 1.00 204.53 ?  419  MET A CE  1 
ATOM   2290 N N   . PRO A 1 420 ? 131.813 149.987 136.962 1.00 156.73 ?  420  PRO A N   1 
ATOM   2291 C CA  . PRO A 1 420 ? 131.092 148.874 136.332 1.00 156.73 ?  420  PRO A CA  1 
ATOM   2292 C C   . PRO A 1 420 ? 131.187 147.499 137.008 1.00 156.73 ?  420  PRO A C   1 
ATOM   2293 O O   . PRO A 1 420 ? 130.154 146.911 137.279 1.00 156.73 ?  420  PRO A O   1 
ATOM   2294 C CB  . PRO A 1 420 ? 131.705 148.837 134.938 1.00 156.73 ?  420  PRO A CB  1 
ATOM   2295 C CG  . PRO A 1 420 ? 132.041 150.266 134.648 1.00 156.73 ?  420  PRO A CG  1 
ATOM   2296 C CD  . PRO A 1 420 ? 132.180 151.001 135.957 1.00 156.73 ?  420  PRO A CD  1 
ATOM   2297 N N   . ARG A 1 421 ? 132.384 147.006 137.295 1.00 168.32 ?  421  ARG A N   1 
ATOM   2298 C CA  . ARG A 1 421 ? 132.534 145.671 137.873 1.00 168.32 ?  421  ARG A CA  1 
ATOM   2299 C C   . ARG A 1 421 ? 132.041 145.605 139.303 1.00 168.32 ?  421  ARG A C   1 
ATOM   2300 O O   . ARG A 1 421 ? 131.455 144.608 139.707 1.00 168.32 ?  421  ARG A O   1 
ATOM   2301 C CB  . ARG A 1 421 ? 133.986 145.216 137.794 1.00 168.32 ?  421  ARG A CB  1 
ATOM   2302 C CG  . ARG A 1 421 ? 134.939 146.298 137.318 1.00 168.32 ?  421  ARG A CG  1 
ATOM   2303 C CD  . ARG A 1 421 ? 135.856 146.761 138.437 1.00 168.32 ?  421  ARG A CD  1 
ATOM   2304 N NE  . ARG A 1 421 ? 135.938 145.784 139.519 1.00 168.32 ?  421  ARG A NE  1 
ATOM   2305 C CZ  . ARG A 1 421 ? 135.940 146.103 140.809 1.00 168.32 ?  421  ARG A CZ  1 
ATOM   2306 N NH1 . ARG A 1 421 ? 135.861 147.373 141.177 1.00 168.32 1  421  ARG A NH1 1 
ATOM   2307 N NH2 . ARG A 1 421 ? 136.017 145.152 141.729 1.00 168.32 ?  421  ARG A NH2 1 
ATOM   2308 N N   . GLU A 1 422 ? 132.276 146.640 140.103 1.00 196.80 ?  422  GLU A N   1 
ATOM   2309 C CA  . GLU A 1 422 ? 131.736 146.628 141.462 1.00 196.80 ?  422  GLU A CA  1 
ATOM   2310 C C   . GLU A 1 422 ? 130.227 146.665 141.435 1.00 196.80 ?  422  GLU A C   1 
ATOM   2311 O O   . GLU A 1 422 ? 129.582 146.023 142.253 1.00 196.80 ?  422  GLU A O   1 
ATOM   2312 C CB  . GLU A 1 422 ? 132.266 147.760 142.337 1.00 196.80 ?  422  GLU A CB  1 
ATOM   2313 C CG  . GLU A 1 422 ? 133.170 148.754 141.659 1.00 196.80 ?  422  GLU A CG  1 
ATOM   2314 C CD  . GLU A 1 422 ? 133.957 149.586 142.649 1.00 196.80 ?  422  GLU A CD  1 
ATOM   2315 O OE1 . GLU A 1 422 ? 134.828 149.021 143.340 1.00 196.80 ?  422  GLU A OE1 1 
ATOM   2316 O OE2 . GLU A 1 422 ? 133.706 150.804 142.738 1.00 196.80 -1 422  GLU A OE2 1 
ATOM   2317 N N   . ALA A 1 423 ? 129.659 147.405 140.492 1.00 179.55 ?  423  ALA A N   1 
ATOM   2318 C CA  . ALA A 1 423 ? 128.214 147.464 140.368 1.00 179.55 ?  423  ALA A CA  1 
ATOM   2319 C C   . ALA A 1 423 ? 127.622 146.072 140.291 1.00 179.55 ?  423  ALA A C   1 
ATOM   2320 O O   . ALA A 1 423 ? 126.759 145.733 141.075 1.00 179.55 ?  423  ALA A O   1 
ATOM   2321 C CB  . ALA A 1 423 ? 127.807 148.287 139.162 1.00 179.55 ?  423  ALA A CB  1 
ATOM   2322 N N   . ILE A 1 424 ? 128.099 145.254 139.365 1.00 178.19 ?  424  ILE A N   1 
ATOM   2323 C CA  . ILE A 1 424 ? 127.603 143.890 139.243 1.00 178.19 ?  424  ILE A CA  1 
ATOM   2324 C C   . ILE A 1 424 ? 127.865 143.069 140.487 1.00 178.19 ?  424  ILE A C   1 
ATOM   2325 O O   . ILE A 1 424 ? 126.975 142.397 140.982 1.00 178.19 ?  424  ILE A O   1 
ATOM   2326 C CB  . ILE A 1 424 ? 128.212 143.170 138.041 1.00 178.19 ?  424  ILE A CB  1 
ATOM   2327 C CG1 . ILE A 1 424 ? 127.724 143.813 136.767 1.00 178.19 ?  424  ILE A CG1 1 
ATOM   2328 C CG2 . ILE A 1 424 ? 127.827 141.708 138.016 1.00 178.19 ?  424  ILE A CG2 1 
ATOM   2329 C CD1 . ILE A 1 424 ? 128.880 144.303 135.964 1.00 178.19 ?  424  ILE A CD1 1 
ATOM   2330 N N   . SER A 1 425 ? 129.079 143.136 141.011 1.00 211.65 ?  425  SER A N   1 
ATOM   2331 C CA  . SER A 1 425 ? 129.406 142.398 142.217 1.00 211.65 ?  425  SER A CA  1 
ATOM   2332 C C   . SER A 1 425 ? 128.378 142.663 143.304 1.00 211.65 ?  425  SER A C   1 
ATOM   2333 O O   . SER A 1 425 ? 127.993 141.751 144.034 1.00 211.65 ?  425  SER A O   1 
ATOM   2334 C CB  . SER A 1 425 ? 130.810 142.750 142.703 1.00 211.65 ?  425  SER A CB  1 
ATOM   2335 O OG  . SER A 1 425 ? 130.771 143.656 143.790 1.00 211.65 ?  425  SER A OG  1 
ATOM   2336 N N   . THR A 1 426 ? 127.923 143.906 143.409 1.00 195.45 ?  426  THR A N   1 
ATOM   2337 C CA  . THR A 1 426 ? 126.933 144.242 144.416 1.00 195.45 ?  426  THR A CA  1 
ATOM   2338 C C   . THR A 1 426 ? 125.516 143.872 143.984 1.00 195.45 ?  426  THR A C   1 
ATOM   2339 O O   . THR A 1 426 ? 124.737 143.348 144.783 1.00 195.45 ?  426  THR A O   1 
ATOM   2340 C CB  . THR A 1 426 ? 127.002 145.725 144.788 1.00 195.45 ?  426  THR A CB  1 
ATOM   2341 O OG1 . THR A 1 426 ? 126.752 146.519 143.626 1.00 195.45 ?  426  THR A OG1 1 
ATOM   2342 C CG2 . THR A 1 426 ? 128.368 146.061 145.335 1.00 195.45 ?  426  THR A CG2 1 
ATOM   2343 N N   . LEU A 1 427 ? 125.182 144.129 142.723 1.00 191.14 ?  427  LEU A N   1 
ATOM   2344 C CA  . LEU A 1 427 ? 123.846 143.814 142.243 1.00 191.14 ?  427  LEU A CA  1 
ATOM   2345 C C   . LEU A 1 427 ? 123.616 142.312 142.232 1.00 191.14 ?  427  LEU A C   1 
ATOM   2346 O O   . LEU A 1 427 ? 122.482 141.865 142.247 1.00 191.14 ?  427  LEU A O   1 
ATOM   2347 C CB  . LEU A 1 427 ? 123.602 144.411 140.854 1.00 191.14 ?  427  LEU A CB  1 
ATOM   2348 C CG  . LEU A 1 427 ? 123.464 145.931 140.743 1.00 191.14 ?  427  LEU A CG  1 
ATOM   2349 C CD1 . LEU A 1 427 ? 123.886 146.447 139.378 1.00 191.14 ?  427  LEU A CD1 1 
ATOM   2350 C CD2 . LEU A 1 427 ? 122.055 146.382 141.058 1.00 191.14 ?  427  LEU A CD2 1 
ATOM   2351 N N   . PHE A 1 428 ? 124.687 141.526 142.227 1.00 213.07 ?  428  PHE A N   1 
ATOM   2352 C CA  . PHE A 1 428 ? 124.567 140.077 142.219 1.00 213.07 ?  428  PHE A CA  1 
ATOM   2353 C C   . PHE A 1 428 ? 124.755 139.536 143.631 1.00 213.07 ?  428  PHE A C   1 
ATOM   2354 O O   . PHE A 1 428 ? 125.219 138.417 143.804 1.00 213.07 ?  428  PHE A O   1 
ATOM   2355 C CB  . PHE A 1 428 ? 125.631 139.459 141.316 1.00 213.07 ?  428  PHE A CB  1 
ATOM   2356 C CG  . PHE A 1 428 ? 125.324 139.521 139.840 1.00 213.07 ?  428  PHE A CG  1 
ATOM   2357 C CD1 . PHE A 1 428 ? 124.307 140.311 139.336 1.00 213.07 ?  428  PHE A CD1 1 
ATOM   2358 C CD2 . PHE A 1 428 ? 126.085 138.783 138.951 1.00 213.07 ?  428  PHE A CD2 1 
ATOM   2359 C CE1 . PHE A 1 428 ? 124.056 140.361 137.983 1.00 213.07 ?  428  PHE A CE1 1 
ATOM   2360 C CE2 . PHE A 1 428 ? 125.832 138.821 137.595 1.00 213.07 ?  428  PHE A CE2 1 
ATOM   2361 C CZ  . PHE A 1 428 ? 124.815 139.613 137.110 1.00 213.07 ?  428  PHE A CZ  1 
ATOM   2362 N N   . ASP A 1 429 ? 124.421 140.327 144.640 1.00 254.83 ?  429  ASP A N   1 
ATOM   2363 C CA  . ASP A 1 429 ? 124.625 139.854 145.996 1.00 254.83 ?  429  ASP A CA  1 
ATOM   2364 C C   . ASP A 1 429 ? 123.473 139.023 146.546 1.00 254.83 ?  429  ASP A C   1 
ATOM   2365 O O   . ASP A 1 429 ? 122.369 139.063 146.009 1.00 254.83 ?  429  ASP A O   1 
ATOM   2366 C CB  . ASP A 1 429 ? 125.254 140.912 146.938 1.00 254.83 ?  429  ASP A CB  1 
ATOM   2367 C CG  . ASP A 1 429 ? 124.254 141.788 147.656 1.00 254.83 ?  429  ASP A CG  1 
ATOM   2368 O OD1 . ASP A 1 429 ? 123.106 141.923 147.234 1.00 254.83 ?  429  ASP A OD1 1 
ATOM   2369 O OD2 . ASP A 1 429 ? 124.650 142.393 148.667 1.00 254.83 -1 429  ASP A OD2 1 
ATOM   2370 N N   . ASN A 1 430 ? 123.719 138.272 147.601 1.00 236.43 ?  430  ASN A N   1 
ATOM   2371 C CA  . ASN A 1 430 ? 122.732 137.356 148.144 1.00 236.43 ?  430  ASN A CA  1 
ATOM   2372 C C   . ASN A 1 430 ? 121.968 138.023 149.263 1.00 236.43 ?  430  ASN A C   1 
ATOM   2373 O O   . ASN A 1 430 ? 121.378 137.351 150.102 1.00 236.43 ?  430  ASN A O   1 
ATOM   2374 C CB  . ASN A 1 430 ? 123.412 136.095 148.665 1.00 236.43 ?  430  ASN A CB  1 
ATOM   2375 C CG  . ASN A 1 430 ? 124.843 136.338 149.088 1.00 236.43 ?  430  ASN A CG  1 
ATOM   2376 O OD1 . ASN A 1 430 ? 125.767 136.201 148.290 1.00 236.43 ?  430  ASN A OD1 1 
ATOM   2377 N ND2 . ASN A 1 430 ? 125.035 136.695 150.353 1.00 236.43 ?  430  ASN A ND2 1 
ATOM   2378 N N   . ASN A 1 431 ? 121.973 139.348 149.285 1.00 238.46 ?  431  ASN A N   1 
ATOM   2379 C CA  . ASN A 1 431 ? 121.289 140.082 150.330 1.00 238.46 ?  431  ASN A CA  1 
ATOM   2380 C C   . ASN A 1 431 ? 120.008 140.666 149.804 1.00 238.46 ?  431  ASN A C   1 
ATOM   2381 O O   . ASN A 1 431 ? 119.732 140.576 148.616 1.00 238.46 ?  431  ASN A O   1 
ATOM   2382 C CB  . ASN A 1 431 ? 122.176 141.214 150.836 1.00 238.46 ?  431  ASN A CB  1 
ATOM   2383 C CG  . ASN A 1 431 ? 123.385 140.714 151.590 1.00 238.46 ?  431  ASN A CG  1 
ATOM   2384 O OD1 . ASN A 1 431 ? 124.505 141.159 151.353 1.00 238.46 ?  431  ASN A OD1 1 
ATOM   2385 N ND2 . ASN A 1 431 ? 123.164 139.783 152.509 1.00 238.46 ?  431  ASN A ND2 1 
ATOM   2386 N N   . THR A 1 432 ? 119.200 141.234 150.683 1.00 235.80 ?  432  THR A N   1 
ATOM   2387 C CA  . THR A 1 432 ? 117.998 141.913 150.243 1.00 235.80 ?  432  THR A CA  1 
ATOM   2388 C C   . THR A 1 432 ? 118.201 143.312 150.747 1.00 235.80 ?  432  THR A C   1 
ATOM   2389 O O   . THR A 1 432 ? 118.107 143.562 151.940 1.00 235.80 ?  432  THR A O   1 
ATOM   2390 C CB  . THR A 1 432 ? 116.731 141.307 150.844 1.00 235.80 ?  432  THR A CB  1 
ATOM   2391 O OG1 . THR A 1 432 ? 116.650 139.922 150.492 1.00 235.80 ?  432  THR A OG1 1 
ATOM   2392 C CG2 . THR A 1 432 ? 115.510 142.019 150.317 1.00 235.80 ?  432  THR A CG2 1 
ATOM   2393 N N   . TRP A 1 433 ? 118.501 144.238 149.854 1.00 195.77 ?  433  TRP A N   1 
ATOM   2394 C CA  . TRP A 1 433 ? 118.820 145.590 150.281 1.00 195.77 ?  433  TRP A CA  1 
ATOM   2395 C C   . TRP A 1 433 ? 117.667 146.286 150.947 1.00 195.77 ?  433  TRP A C   1 
ATOM   2396 O O   . TRP A 1 433 ? 117.863 147.101 151.841 1.00 195.77 ?  433  TRP A O   1 
ATOM   2397 C CB  . TRP A 1 433 ? 119.255 146.407 149.084 1.00 195.77 ?  433  TRP A CB  1 
ATOM   2398 C CG  . TRP A 1 433 ? 120.483 145.925 148.429 1.00 195.77 ?  433  TRP A CG  1 
ATOM   2399 C CD1 . TRP A 1 433 ? 121.452 145.138 148.969 1.00 195.77 ?  433  TRP A CD1 1 
ATOM   2400 C CD2 . TRP A 1 433 ? 120.892 146.206 147.094 1.00 195.77 ?  433  TRP A CD2 1 
ATOM   2401 N NE1 . TRP A 1 433 ? 122.435 144.903 148.050 1.00 195.77 ?  433  TRP A NE1 1 
ATOM   2402 C CE2 . TRP A 1 433 ? 122.117 145.557 146.890 1.00 195.77 ?  433  TRP A CE2 1 
ATOM   2403 C CE3 . TRP A 1 433 ? 120.339 146.945 146.049 1.00 195.77 ?  433  TRP A CE3 1 
ATOM   2404 C CZ2 . TRP A 1 433 ? 122.795 145.623 145.689 1.00 195.77 ?  433  TRP A CZ2 1 
ATOM   2405 C CZ3 . TRP A 1 433 ? 121.016 147.008 144.862 1.00 195.77 ?  433  TRP A CZ3 1 
ATOM   2406 C CH2 . TRP A 1 433 ? 122.227 146.345 144.687 1.00 195.77 ?  433  TRP A CH2 1 
ATOM   2407 N N   . VAL A 1 434 ? 116.456 145.966 150.519 1.00 221.24 ?  434  VAL A N   1 
ATOM   2408 C CA  . VAL A 1 434 ? 115.275 146.605 151.072 1.00 221.24 ?  434  VAL A CA  1 
ATOM   2409 C C   . VAL A 1 434 ? 114.961 146.084 152.476 1.00 221.24 ?  434  VAL A C   1 
ATOM   2410 O O   . VAL A 1 434 ? 114.235 146.724 153.234 1.00 221.24 ?  434  VAL A O   1 
ATOM   2411 C CB  . VAL A 1 434 ? 114.093 146.502 150.081 1.00 221.24 ?  434  VAL A CB  1 
ATOM   2412 C CG1 . VAL A 1 434 ? 113.219 145.286 150.344 1.00 221.24 ?  434  VAL A CG1 1 
ATOM   2413 C CG2 . VAL A 1 434 ? 113.307 147.800 150.043 1.00 221.24 ?  434  VAL A CG2 1 
ATOM   2414 N N   . LYS A 1 435 ? 115.543 144.949 152.846 1.00 239.32 ?  435  LYS A N   1 
ATOM   2415 C CA  . LYS A 1 435 ? 115.345 144.412 154.185 1.00 239.32 ?  435  LYS A CA  1 
ATOM   2416 C C   . LYS A 1 435 ? 116.397 144.992 155.113 1.00 239.32 ?  435  LYS A C   1 
ATOM   2417 O O   . LYS A 1 435 ? 116.075 145.473 156.195 1.00 239.32 ?  435  LYS A O   1 
ATOM   2418 C CB  . LYS A 1 435 ? 115.454 142.889 154.172 1.00 239.32 ?  435  LYS A CB  1 
ATOM   2419 C CG  . LYS A 1 435 ? 114.141 142.139 154.336 1.00 239.32 ?  435  LYS A CG  1 
ATOM   2420 C CD  . LYS A 1 435 ? 112.935 143.001 154.003 1.00 239.32 ?  435  LYS A CD  1 
ATOM   2421 C CE  . LYS A 1 435 ? 112.060 142.348 152.947 1.00 239.32 ?  435  LYS A CE  1 
ATOM   2422 N NZ  . LYS A 1 435 ? 110.974 143.265 152.503 1.00 239.32 1  435  LYS A NZ  1 
ATOM   2423 N N   . HIS A 1 436 ? 117.656 144.959 154.692 1.00 281.37 ?  436  HIS A N   1 
ATOM   2424 C CA  . HIS A 1 436 ? 118.741 145.481 155.520 1.00 281.37 ?  436  HIS A CA  1 
ATOM   2425 C C   . HIS A 1 436 ? 119.044 146.919 155.156 1.00 281.37 ?  436  HIS A C   1 
ATOM   2426 O O   . HIS A 1 436 ? 120.171 147.250 154.800 1.00 281.37 ?  436  HIS A O   1 
ATOM   2427 C CB  . HIS A 1 436 ? 120.017 144.638 155.391 1.00 281.37 ?  436  HIS A CB  1 
ATOM   2428 C CG  . HIS A 1 436 ? 119.784 143.229 154.942 1.00 281.37 ?  436  HIS A CG  1 
ATOM   2429 N ND1 . HIS A 1 436 ? 118.935 142.363 155.597 1.00 281.37 ?  436  HIS A ND1 1 
ATOM   2430 C CD2 . HIS A 1 436 ? 120.317 142.524 153.916 1.00 281.37 ?  436  HIS A CD2 1 
ATOM   2431 C CE1 . HIS A 1 436 ? 118.935 141.195 154.978 1.00 281.37 ?  436  HIS A CE1 1 
ATOM   2432 N NE2 . HIS A 1 436 ? 119.766 141.267 153.955 1.00 281.37 ?  436  HIS A NE2 1 
ATOM   2433 N N   . ALA A 1 437 ? 118.036 147.774 155.234 1.00 293.73 ?  437  ALA A N   1 
ATOM   2434 C CA  . ALA A 1 437 ? 118.224 149.175 154.908 1.00 293.73 ?  437  ALA A CA  1 
ATOM   2435 C C   . ALA A 1 437 ? 118.452 149.941 156.189 1.00 293.73 ?  437  ALA A C   1 
ATOM   2436 O O   . ALA A 1 437 ? 119.230 150.892 156.219 1.00 293.73 ?  437  ALA A O   1 
ATOM   2437 C CB  . ALA A 1 437 ? 117.008 149.711 154.175 1.00 293.73 ?  437  ALA A CB  1 
ATOM   2438 N N   . GLY A 1 438 ? 117.775 149.525 157.257 1.00 306.05 ?  438  GLY A N   1 
ATOM   2439 C CA  . GLY A 1 438 ? 117.961 150.165 158.546 1.00 306.05 ?  438  GLY A CA  1 
ATOM   2440 C C   . GLY A 1 438 ? 119.382 149.957 158.996 1.00 306.05 ?  438  GLY A C   1 
ATOM   2441 O O   . GLY A 1 438 ? 120.007 150.872 159.526 1.00 306.05 ?  438  GLY A O   1 
ATOM   2442 N N   . ASP A 1 439 ? 119.903 148.754 158.794 1.00 298.16 ?  439  ASP A N   1 
ATOM   2443 C CA  . ASP A 1 439 ? 121.294 148.495 159.118 1.00 298.16 ?  439  ASP A CA  1 
ATOM   2444 C C   . ASP A 1 439 ? 122.070 148.256 157.842 1.00 298.16 ?  439  ASP A C   1 
ATOM   2445 O O   . ASP A 1 439 ? 121.976 147.187 157.244 1.00 298.16 ?  439  ASP A O   1 
ATOM   2446 C CB  . ASP A 1 439 ? 121.423 147.276 160.028 1.00 298.16 ?  439  ASP A CB  1 
ATOM   2447 C CG  . ASP A 1 439 ? 122.868 146.923 160.326 1.00 298.16 ?  439  ASP A CG  1 
ATOM   2448 O OD1 . ASP A 1 439 ? 123.611 147.803 160.807 1.00 298.16 ?  439  ASP A OD1 1 
ATOM   2449 O OD2 . ASP A 1 439 ? 123.260 145.766 160.068 1.00 298.16 -1 439  ASP A OD2 1 
ATOM   2450 N N   . PRO A 1 440 ? 122.848 149.252 157.407 1.00 287.15 ?  440  PRO A N   1 
ATOM   2451 C CA  . PRO A 1 440 ? 123.688 148.997 156.242 1.00 287.15 ?  440  PRO A CA  1 
ATOM   2452 C C   . PRO A 1 440 ? 125.017 148.421 156.706 1.00 287.15 ?  440  PRO A C   1 
ATOM   2453 O O   . PRO A 1 440 ? 125.099 147.926 157.834 1.00 287.15 ?  440  PRO A O   1 
ATOM   2454 C CB  . PRO A 1 440 ? 123.886 150.389 155.631 1.00 287.15 ?  440  PRO A CB  1 
ATOM   2455 C CG  . PRO A 1 440 ? 123.197 151.359 156.544 1.00 287.15 ?  440  PRO A CG  1 
ATOM   2456 C CD  . PRO A 1 440 ? 122.939 150.653 157.836 1.00 287.15 ?  440  PRO A CD  1 
ATOM   2457 N N   . GLU A 1 441 ? 126.040 148.462 155.860 1.00 298.65 ?  441  GLU A N   1 
ATOM   2458 C CA  . GLU A 1 441 ? 127.357 147.906 156.200 1.00 298.65 ?  441  GLU A CA  1 
ATOM   2459 C C   . GLU A 1 441 ? 127.306 146.455 156.660 1.00 298.65 ?  441  GLU A C   1 
ATOM   2460 O O   . GLU A 1 441 ? 128.195 145.997 157.372 1.00 298.65 ?  441  GLU A O   1 
ATOM   2461 C CB  . GLU A 1 441 ? 128.103 148.788 157.212 1.00 298.65 ?  441  GLU A CB  1 
ATOM   2462 C CG  . GLU A 1 441 ? 128.210 150.249 156.806 1.00 298.65 ?  441  GLU A CG  1 
ATOM   2463 C CD  . GLU A 1 441 ? 127.218 151.130 157.541 1.00 298.65 ?  441  GLU A CD  1 
ATOM   2464 O OE1 . GLU A 1 441 ? 126.771 150.736 158.640 1.00 298.65 ?  441  GLU A OE1 1 
ATOM   2465 O OE2 . GLU A 1 441 ? 126.877 152.211 157.016 1.00 298.65 -1 441  GLU A OE2 1 
ATOM   2466 N N   . SER A 1 442 ? 126.276 145.726 156.251 1.00 305.90 ?  442  SER A N   1 
ATOM   2467 C CA  . SER A 1 442 ? 126.160 144.318 156.582 1.00 305.90 ?  442  SER A CA  1 
ATOM   2468 C C   . SER A 1 442 ? 126.153 143.729 155.205 1.00 305.90 ?  442  SER A C   1 
ATOM   2469 O O   . SER A 1 442 ? 126.282 142.521 155.025 1.00 305.90 ?  442  SER A O   1 
ATOM   2470 C CB  . SER A 1 442 ? 124.828 144.049 157.269 1.00 305.90 ?  442  SER A CB  1 
ATOM   2471 O OG  . SER A 1 442 ? 123.839 144.961 156.829 1.00 305.90 ?  442  SER A OG  1 
ATOM   2472 N N   . LEU A 1 443 ? 126.002 144.599 154.217 1.00 251.68 ?  443  LEU A N   1 
ATOM   2473 C CA  . LEU A 1 443 ? 125.984 144.160 152.841 1.00 251.68 ?  443  LEU A CA  1 
ATOM   2474 C C   . LEU A 1 443 ? 127.357 144.425 152.266 1.00 251.68 ?  443  LEU A C   1 
ATOM   2475 O O   . LEU A 1 443 ? 127.656 144.011 151.149 1.00 251.68 ?  443  LEU A O   1 
ATOM   2476 C CB  . LEU A 1 443 ? 124.908 144.925 152.083 1.00 251.68 ?  443  LEU A CB  1 
ATOM   2477 C CG  . LEU A 1 443 ? 123.753 145.435 152.941 1.00 251.68 ?  443  LEU A CG  1 
ATOM   2478 C CD1 . LEU A 1 443 ? 123.818 146.940 153.101 1.00 251.68 ?  443  LEU A CD1 1 
ATOM   2479 C CD2 . LEU A 1 443 ? 122.424 145.024 152.346 1.00 251.68 ?  443  LEU A CD2 1 
ATOM   2480 N N   . GLY A 1 444 ? 128.199 145.114 153.026 1.00 215.61 ?  444  GLY A N   1 
ATOM   2481 C CA  . GLY A 1 444 ? 129.558 145.358 152.584 1.00 215.61 ?  444  GLY A CA  1 
ATOM   2482 C C   . GLY A 1 444 ? 129.665 146.463 151.568 1.00 215.61 ?  444  GLY A C   1 
ATOM   2483 O O   . GLY A 1 444 ? 129.418 147.623 151.882 1.00 215.61 ?  444  GLY A O   1 
ATOM   2484 N N   . GLN A 1 445 ? 130.024 146.109 150.340 1.00 206.13 ?  445  GLN A N   1 
ATOM   2485 C CA  . GLN A 1 445 ? 130.158 147.101 149.284 1.00 206.13 ?  445  GLN A CA  1 
ATOM   2486 C C   . GLN A 1 445 ? 128.804 147.461 148.714 1.00 206.13 ?  445  GLN A C   1 
ATOM   2487 O O   . GLN A 1 445 ? 128.686 148.402 147.936 1.00 206.13 ?  445  GLN A O   1 
ATOM   2488 C CB  . GLN A 1 445 ? 131.067 146.577 148.180 1.00 206.13 ?  445  GLN A CB  1 
ATOM   2489 C CG  . GLN A 1 445 ? 132.148 147.557 147.758 1.00 206.13 ?  445  GLN A CG  1 
ATOM   2490 C CD  . GLN A 1 445 ? 132.395 147.550 146.264 1.00 206.13 ?  445  GLN A CD  1 
ATOM   2491 O OE1 . GLN A 1 445 ? 131.824 146.746 145.529 1.00 206.13 ?  445  GLN A OE1 1 
ATOM   2492 N NE2 . GLN A 1 445 ? 133.255 148.450 145.806 1.00 206.13 ?  445  GLN A NE2 1 
ATOM   2493 N N   . SER A 1 446 ? 127.771 146.728 149.111 1.00 199.99 ?  446  SER A N   1 
ATOM   2494 C CA  . SER A 1 446 ? 126.430 147.001 148.631 1.00 199.99 ?  446  SER A CA  1 
ATOM   2495 C C   . SER A 1 446 ? 125.717 147.948 149.568 1.00 199.99 ?  446  SER A C   1 
ATOM   2496 O O   . SER A 1 446 ? 124.494 148.041 149.544 1.00 199.99 ?  446  SER A O   1 
ATOM   2497 C CB  . SER A 1 446 ? 125.661 145.696 148.493 1.00 199.99 ?  446  SER A CB  1 
ATOM   2498 O OG  . SER A 1 446 ? 126.551 144.607 148.376 1.00 199.99 ?  446  SER A OG  1 
ATOM   2499 N N   . ALA A 1 447 ? 126.475 148.660 150.390 1.00 185.10 ?  447  ALA A N   1 
ATOM   2500 C CA  . ALA A 1 447 ? 125.895 149.622 151.309 1.00 185.10 ?  447  ALA A CA  1 
ATOM   2501 C C   . ALA A 1 447 ? 125.826 150.969 150.639 1.00 185.10 ?  447  ALA A C   1 
ATOM   2502 O O   . ALA A 1 447 ? 125.233 151.901 151.173 1.00 185.10 ?  447  ALA A O   1 
ATOM   2503 C CB  . ALA A 1 447 ? 126.734 149.711 152.564 1.00 185.10 ?  447  ALA A CB  1 
ATOM   2504 N N   . VAL A 1 448 ? 126.424 151.081 149.459 1.00 148.45 ?  448  VAL A N   1 
ATOM   2505 C CA  . VAL A 1 448 ? 126.382 152.326 148.711 1.00 148.45 ?  448  VAL A CA  1 
ATOM   2506 C C   . VAL A 1 448 ? 125.041 152.446 148.024 1.00 148.45 ?  448  VAL A C   1 
ATOM   2507 O O   . VAL A 1 448 ? 124.683 153.511 147.526 1.00 148.45 ?  448  VAL A O   1 
ATOM   2508 C CB  . VAL A 1 448 ? 127.504 152.375 147.664 1.00 148.45 ?  448  VAL A CB  1 
ATOM   2509 C CG1 . VAL A 1 448 ? 128.856 152.192 148.332 1.00 148.45 ?  448  VAL A CG1 1 
ATOM   2510 C CG2 . VAL A 1 448 ? 127.291 151.300 146.624 1.00 148.45 ?  448  VAL A CG2 1 
ATOM   2511 N N   . TRP A 1 449 ? 124.285 151.358 148.007 1.00 178.59 ?  449  TRP A N   1 
ATOM   2512 C CA  . TRP A 1 449 ? 122.979 151.373 147.399 1.00 178.59 ?  449  TRP A CA  1 
ATOM   2513 C C   . TRP A 1 449 ? 121.980 151.877 148.405 1.00 178.59 ?  449  TRP A C   1 
ATOM   2514 O O   . TRP A 1 449 ? 120.962 152.450 148.049 1.00 178.59 ?  449  TRP A O   1 
ATOM   2515 C CB  . TRP A 1 449 ? 122.623 149.975 146.934 1.00 178.59 ?  449  TRP A CB  1 
ATOM   2516 C CG  . TRP A 1 449 ? 123.485 149.530 145.815 1.00 178.59 ?  449  TRP A CG  1 
ATOM   2517 C CD1 . TRP A 1 449 ? 124.629 148.800 145.906 1.00 178.59 ?  449  TRP A CD1 1 
ATOM   2518 C CD2 . TRP A 1 449 ? 123.290 149.800 144.423 1.00 178.59 ?  449  TRP A CD2 1 
ATOM   2519 N NE1 . TRP A 1 449 ? 125.154 148.590 144.661 1.00 178.59 ?  449  TRP A NE1 1 
ATOM   2520 C CE2 . TRP A 1 449 ? 124.351 149.191 143.731 1.00 178.59 ?  449  TRP A CE2 1 
ATOM   2521 C CE3 . TRP A 1 449 ? 122.313 150.484 143.695 1.00 178.59 ?  449  TRP A CE3 1 
ATOM   2522 C CZ2 . TRP A 1 449 ? 124.470 149.253 142.348 1.00 178.59 ?  449  TRP A CZ2 1 
ATOM   2523 C CZ3 . TRP A 1 449 ? 122.433 150.545 142.326 1.00 178.59 ?  449  TRP A CZ3 1 
ATOM   2524 C CH2 . TRP A 1 449 ? 123.502 149.931 141.666 1.00 178.59 ?  449  TRP A CH2 1 
ATOM   2525 N N   . ILE A 1 450 ? 122.274 151.676 149.677 1.00 153.23 ?  450  ILE A N   1 
ATOM   2526 C CA  . ILE A 1 450 ? 121.391 152.185 150.706 1.00 153.23 ?  450  ILE A CA  1 
ATOM   2527 C C   . ILE A 1 450 ? 121.747 153.642 150.952 1.00 153.23 ?  450  ILE A C   1 
ATOM   2528 O O   . ILE A 1 450 ? 122.842 153.960 151.413 1.00 153.23 ?  450  ILE A O   1 
ATOM   2529 C CB  . ILE A 1 450 ? 121.416 151.315 151.985 1.00 153.23 ?  450  ILE A CB  1 
ATOM   2530 C CG1 . ILE A 1 450 ? 120.562 150.063 151.783 1.00 153.23 ?  450  ILE A CG1 1 
ATOM   2531 C CG2 . ILE A 1 450 ? 120.858 152.071 153.179 1.00 153.23 ?  450  ILE A CG2 1 
ATOM   2532 C CD1 . ILE A 1 450 ? 121.305 148.865 151.243 1.00 153.23 ?  450  ILE A CD1 1 
ATOM   2533 N N   . HIS A 1 451 ? 120.841 154.537 150.585 1.00 176.34 ?  451  HIS A N   1 
ATOM   2534 C CA  . HIS A 1 451 ? 121.070 155.953 150.806 1.00 176.34 ?  451  HIS A CA  1 
ATOM   2535 C C   . HIS A 1 451 ? 120.305 156.334 152.054 1.00 176.34 ?  451  HIS A C   1 
ATOM   2536 O O   . HIS A 1 451 ? 119.187 155.862 152.248 1.00 176.34 ?  451  HIS A O   1 
ATOM   2537 C CB  . HIS A 1 451 ? 120.576 156.767 149.605 1.00 176.34 ?  451  HIS A CB  1 
ATOM   2538 C CG  . HIS A 1 451 ? 120.897 158.225 149.691 1.00 176.34 ?  451  HIS A CG  1 
ATOM   2539 N ND1 . HIS A 1 451 ? 122.151 158.727 149.423 1.00 176.34 ?  451  HIS A ND1 1 
ATOM   2540 C CD2 . HIS A 1 451 ? 120.133 159.289 150.033 1.00 176.34 ?  451  HIS A CD2 1 
ATOM   2541 C CE1 . HIS A 1 451 ? 122.144 160.036 149.589 1.00 176.34 ?  451  HIS A CE1 1 
ATOM   2542 N NE2 . HIS A 1 451 ? 120.930 160.402 149.959 1.00 176.34 ?  451  HIS A NE2 1 
ATOM   2543 N N   . PRO A 1 452 ? 120.900 157.168 152.922 1.00 207.20 ?  452  PRO A N   1 
ATOM   2544 C CA  . PRO A 1 452 ? 120.225 157.636 154.135 1.00 207.20 ?  452  PRO A CA  1 
ATOM   2545 C C   . PRO A 1 452 ? 118.753 157.987 153.956 1.00 207.20 ?  452  PRO A C   1 
ATOM   2546 O O   . PRO A 1 452 ? 117.924 157.516 154.729 1.00 207.20 ?  452  PRO A O   1 
ATOM   2547 C CB  . PRO A 1 452 ? 121.006 158.903 154.491 1.00 207.20 ?  452  PRO A CB  1 
ATOM   2548 C CG  . PRO A 1 452 ? 122.284 158.847 153.701 1.00 207.20 ?  452  PRO A CG  1 
ATOM   2549 C CD  . PRO A 1 452 ? 122.314 157.564 152.925 1.00 207.20 ?  452  PRO A CD  1 
ATOM   2550 N N   . ARG A 1 453 ? 118.429 158.806 152.962 1.00 216.41 ?  453  ARG A N   1 
ATOM   2551 C CA  . ARG A 1 453 ? 117.051 159.227 152.759 1.00 216.41 ?  453  ARG A CA  1 
ATOM   2552 C C   . ARG A 1 453 ? 116.343 158.450 151.665 1.00 216.41 ?  453  ARG A C   1 
ATOM   2553 O O   . ARG A 1 453 ? 115.293 157.859 151.903 1.00 216.41 ?  453  ARG A O   1 
ATOM   2554 C CB  . ARG A 1 453 ? 117.002 160.719 152.444 1.00 216.41 ?  453  ARG A CB  1 
ATOM   2555 C CG  . ARG A 1 453 ? 118.131 161.522 153.065 1.00 216.41 ?  453  ARG A CG  1 
ATOM   2556 C CD  . ARG A 1 453 ? 118.813 162.391 152.025 1.00 216.41 ?  453  ARG A CD  1 
ATOM   2557 N NE  . ARG A 1 453 ? 118.040 162.453 150.789 1.00 216.41 ?  453  ARG A NE  1 
ATOM   2558 C CZ  . ARG A 1 453 ? 118.295 163.292 149.793 1.00 216.41 ?  453  ARG A CZ  1 
ATOM   2559 N NH1 . ARG A 1 453 ? 117.539 163.284 148.705 1.00 216.41 1  453  ARG A NH1 1 
ATOM   2560 N NH2 . ARG A 1 453 ? 119.308 164.143 149.886 1.00 216.41 ?  453  ARG A NH2 1 
ATOM   2561 N N   . VAL A 1 454 ? 116.905 158.448 150.464 1.00 199.01 ?  454  VAL A N   1 
ATOM   2562 C CA  . VAL A 1 454 ? 116.265 157.777 149.336 1.00 199.01 ?  454  VAL A CA  1 
ATOM   2563 C C   . VAL A 1 454 ? 116.228 156.261 149.495 1.00 199.01 ?  454  VAL A C   1 
ATOM   2564 O O   . VAL A 1 454 ? 117.248 155.639 149.779 1.00 199.01 ?  454  VAL A O   1 
ATOM   2565 C CB  . VAL A 1 454 ? 116.949 158.176 148.014 1.00 199.01 ?  454  VAL A CB  1 
ATOM   2566 C CG1 . VAL A 1 454 ? 116.117 157.765 146.815 1.00 199.01 ?  454  VAL A CG1 1 
ATOM   2567 C CG2 . VAL A 1 454 ? 117.183 159.675 147.984 1.00 199.01 ?  454  VAL A CG2 1 
ATOM   2568 N N   . ASN A 1 455 ? 115.054 155.664 149.316 1.00 173.98 ?  455  ASN A N   1 
ATOM   2569 C CA  . ASN A 1 455 ? 114.913 154.214 149.419 1.00 173.98 ?  455  ASN A CA  1 
ATOM   2570 C C   . ASN A 1 455 ? 115.717 153.501 148.353 1.00 173.98 ?  455  ASN A C   1 
ATOM   2571 O O   . ASN A 1 455 ? 115.756 153.953 147.218 1.00 173.98 ?  455  ASN A O   1 
ATOM   2572 C CB  . ASN A 1 455 ? 113.439 153.831 149.281 1.00 173.98 ?  455  ASN A CB  1 
ATOM   2573 C CG  . ASN A 1 455 ? 113.199 152.341 149.428 1.00 173.98 ?  455  ASN A CG  1 
ATOM   2574 O OD1 . ASN A 1 455 ? 113.700 151.705 150.354 1.00 173.98 ?  455  ASN A OD1 1 
ATOM   2575 N ND2 . ASN A 1 455 ? 112.425 151.778 148.513 1.00 173.98 ?  455  ASN A ND2 1 
ATOM   2576 N N   . VAL A 1 456 ? 116.335 152.378 148.706 1.00 157.56 ?  456  VAL A N   1 
ATOM   2577 C CA  . VAL A 1 456 ? 117.121 151.595 147.752 1.00 157.56 ?  456  VAL A CA  1 
ATOM   2578 C C   . VAL A 1 456 ? 116.496 151.458 146.381 1.00 157.56 ?  456  VAL A C   1 
ATOM   2579 O O   . VAL A 1 456 ? 117.145 151.739 145.393 1.00 157.56 ?  456  VAL A O   1 
ATOM   2580 C CB  . VAL A 1 456 ? 117.381 150.178 148.273 1.00 157.56 ?  456  VAL A CB  1 
ATOM   2581 C CG1 . VAL A 1 456 ? 118.806 149.778 147.958 1.00 157.56 ?  456  VAL A CG1 1 
ATOM   2582 C CG2 . VAL A 1 456 ? 117.109 150.103 149.765 1.00 157.56 ?  456  VAL A CG2 1 
ATOM   2583 N N   . VAL A 1 457 ? 115.245 151.026 146.316 1.00 156.78 ?  457  VAL A N   1 
ATOM   2584 C CA  . VAL A 1 457 ? 114.563 150.836 145.041 1.00 156.78 ?  457  VAL A CA  1 
ATOM   2585 C C   . VAL A 1 457 ? 114.719 152.036 144.114 1.00 156.78 ?  457  VAL A C   1 
ATOM   2586 O O   . VAL A 1 457 ? 115.080 151.881 142.952 1.00 156.78 ?  457  VAL A O   1 
ATOM   2587 C CB  . VAL A 1 457 ? 113.079 150.477 145.272 1.00 156.78 ?  457  VAL A CB  1 
ATOM   2588 C CG1 . VAL A 1 457 ? 112.273 150.548 143.987 1.00 156.78 ?  457  VAL A CG1 1 
ATOM   2589 C CG2 . VAL A 1 457 ? 112.975 149.089 145.878 1.00 156.78 ?  457  VAL A CG2 1 
ATOM   2590 N N   . ILE A 1 458 ? 114.494 153.236 144.631 1.00 182.65 ?  458  ILE A N   1 
ATOM   2591 C CA  . ILE A 1 458 ? 114.617 154.433 143.815 1.00 182.65 ?  458  ILE A CA  1 
ATOM   2592 C C   . ILE A 1 458 ? 116.048 154.723 143.393 1.00 182.65 ?  458  ILE A C   1 
ATOM   2593 O O   . ILE A 1 458 ? 116.267 155.244 142.313 1.00 182.65 ?  458  ILE A O   1 
ATOM   2594 C CB  . ILE A 1 458 ? 114.019 155.657 144.517 1.00 182.65 ?  458  ILE A CB  1 
ATOM   2595 C CG1 . ILE A 1 458 ? 112.959 155.217 145.526 1.00 182.65 ?  458  ILE A CG1 1 
ATOM   2596 C CG2 . ILE A 1 458 ? 113.406 156.610 143.503 1.00 182.65 ?  458  ILE A CG2 1 
ATOM   2597 C CD1 . ILE A 1 458 ? 112.388 156.354 146.342 1.00 182.65 ?  458  ILE A CD1 1 
ATOM   2598 N N   . ILE A 1 459 ? 117.033 154.385 144.214 1.00 168.11 ?  459  ILE A N   1 
ATOM   2599 C CA  . ILE A 1 459 ? 118.415 154.568 143.774 1.00 168.11 ?  459  ILE A CA  1 
ATOM   2600 C C   . ILE A 1 459 ? 118.826 153.556 142.703 1.00 168.11 ?  459  ILE A C   1 
ATOM   2601 O O   . ILE A 1 459 ? 119.635 153.880 141.844 1.00 168.11 ?  459  ILE A O   1 
ATOM   2602 C CB  . ILE A 1 459 ? 119.438 154.698 144.941 1.00 168.11 ?  459  ILE A CB  1 
ATOM   2603 C CG1 . ILE A 1 459 ? 120.443 153.550 144.965 1.00 168.11 ?  459  ILE A CG1 1 
ATOM   2604 C CG2 . ILE A 1 459 ? 118.749 154.875 146.281 1.00 168.11 ?  459  ILE A CG2 1 
ATOM   2605 C CD1 . ILE A 1 459 ? 121.872 154.037 144.962 1.00 168.11 ?  459  ILE A CD1 1 
ATOM   2606 N N   . ILE A 1 460 ? 118.245 152.355 142.707 1.00 157.05 ?  460  ILE A N   1 
ATOM   2607 C CA  . ILE A 1 460 ? 118.535 151.391 141.647 1.00 157.05 ?  460  ILE A CA  1 
ATOM   2608 C C   . ILE A 1 460 ? 117.842 151.873 140.396 1.00 157.05 ?  460  ILE A C   1 
ATOM   2609 O O   . ILE A 1 460 ? 118.357 151.718 139.296 1.00 157.05 ?  460  ILE A O   1 
ATOM   2610 C CB  . ILE A 1 460 ? 118.059 149.961 141.971 1.00 157.05 ?  460  ILE A CB  1 
ATOM   2611 C CG1 . ILE A 1 460 ? 118.359 149.582 143.411 1.00 157.05 ?  460  ILE A CG1 1 
ATOM   2612 C CG2 . ILE A 1 460 ? 118.777 148.952 141.102 1.00 157.05 ?  460  ILE A CG2 1 
ATOM   2613 C CD1 . ILE A 1 460 ? 117.528 148.415 143.893 1.00 157.05 ?  460  ILE A CD1 1 
ATOM   2614 N N   . PHE A 1 461 ? 116.673 152.478 140.558 1.00 201.00 ?  461  PHE A N   1 
ATOM   2615 C CA  . PHE A 1 461 ? 115.946 153.026 139.424 1.00 201.00 ?  461  PHE A CA  1 
ATOM   2616 C C   . PHE A 1 461 ? 116.747 154.163 138.822 1.00 201.00 ?  461  PHE A C   1 
ATOM   2617 O O   . PHE A 1 461 ? 116.849 154.277 137.611 1.00 201.00 ?  461  PHE A O   1 
ATOM   2618 C CB  . PHE A 1 461 ? 114.568 153.502 139.887 1.00 201.00 ?  461  PHE A CB  1 
ATOM   2619 C CG  . PHE A 1 461 ? 113.872 154.412 138.925 1.00 201.00 ?  461  PHE A CG  1 
ATOM   2620 C CD1 . PHE A 1 461 ? 113.313 153.912 137.762 1.00 201.00 ?  461  PHE A CD1 1 
ATOM   2621 C CD2 . PHE A 1 461 ? 113.751 155.765 139.196 1.00 201.00 ?  461  PHE A CD2 1 
ATOM   2622 C CE1 . PHE A 1 461 ? 112.664 154.746 136.877 1.00 201.00 ?  461  PHE A CE1 1 
ATOM   2623 C CE2 . PHE A 1 461 ? 113.108 156.605 138.313 1.00 201.00 ?  461  PHE A CE2 1 
ATOM   2624 C CZ  . PHE A 1 461 ? 112.561 156.095 137.153 1.00 201.00 ?  461  PHE A CZ  1 
ATOM   2625 N N   . LEU A 1 462 ? 117.337 154.996 139.666 1.00 190.40 ?  462  LEU A N   1 
ATOM   2626 C CA  . LEU A 1 462 ? 118.101 156.123 139.170 1.00 190.40 ?  462  LEU A CA  1 
ATOM   2627 C C   . LEU A 1 462 ? 119.411 155.670 138.580 1.00 190.40 ?  462  LEU A C   1 
ATOM   2628 O O   . LEU A 1 462 ? 119.893 156.285 137.649 1.00 190.40 ?  462  LEU A O   1 
ATOM   2629 C CB  . LEU A 1 462 ? 118.334 157.148 140.266 1.00 190.40 ?  462  LEU A CB  1 
ATOM   2630 C CG  . LEU A 1 462 ? 117.531 158.440 140.177 1.00 190.40 ?  462  LEU A CG  1 
ATOM   2631 C CD1 . LEU A 1 462 ? 116.708 158.488 138.900 1.00 190.40 ?  462  LEU A CD1 1 
ATOM   2632 C CD2 . LEU A 1 462 ? 116.648 158.601 141.402 1.00 190.40 ?  462  LEU A CD2 1 
ATOM   2633 N N   . PHE A 1 463 ? 119.995 154.599 139.103 1.00 168.22 ?  463  PHE A N   1 
ATOM   2634 C CA  . PHE A 1 463 ? 121.204 154.049 138.513 1.00 168.22 ?  463  PHE A CA  1 
ATOM   2635 C C   . PHE A 1 463 ? 120.828 153.629 137.119 1.00 168.22 ?  463  PHE A C   1 
ATOM   2636 O O   . PHE A 1 463 ? 121.477 154.010 136.170 1.00 168.22 ?  463  PHE A O   1 
ATOM   2637 C CB  . PHE A 1 463 ? 121.687 152.842 139.324 1.00 168.22 ?  463  PHE A CB  1 
ATOM   2638 C CG  . PHE A 1 463 ? 122.874 152.120 138.737 1.00 168.22 ?  463  PHE A CG  1 
ATOM   2639 C CD1 . PHE A 1 463 ? 124.159 152.556 138.981 1.00 168.22 ?  463  PHE A CD1 1 
ATOM   2640 C CD2 . PHE A 1 463 ? 122.705 150.973 137.986 1.00 168.22 ?  463  PHE A CD2 1 
ATOM   2641 C CE1 . PHE A 1 463 ? 125.249 151.885 138.469 1.00 168.22 ?  463  PHE A CE1 1 
ATOM   2642 C CE2 . PHE A 1 463 ? 123.787 150.298 137.460 1.00 168.22 ?  463  PHE A CE2 1 
ATOM   2643 C CZ  . PHE A 1 463 ? 125.062 150.754 137.704 1.00 168.22 ?  463  PHE A CZ  1 
ATOM   2644 N N   . PHE A 1 464 ? 119.758 152.859 136.993 1.00 193.47 ?  464  PHE A N   1 
ATOM   2645 C CA  . PHE A 1 464 ? 119.327 152.379 135.695 1.00 193.47 ?  464  PHE A CA  1 
ATOM   2646 C C   . PHE A 1 464 ? 119.080 153.507 134.710 1.00 193.47 ?  464  PHE A C   1 
ATOM   2647 O O   . PHE A 1 464 ? 119.555 153.456 133.591 1.00 193.47 ?  464  PHE A O   1 
ATOM   2648 C CB  . PHE A 1 464 ? 118.073 151.515 135.840 1.00 193.47 ?  464  PHE A CB  1 
ATOM   2649 C CG  . PHE A 1 464 ? 117.572 150.961 134.543 1.00 193.47 ?  464  PHE A CG  1 
ATOM   2650 C CD1 . PHE A 1 464 ? 118.253 149.946 133.911 1.00 193.47 ?  464  PHE A CD1 1 
ATOM   2651 C CD2 . PHE A 1 464 ? 116.427 151.464 133.952 1.00 193.47 ?  464  PHE A CD2 1 
ATOM   2652 C CE1 . PHE A 1 464 ? 117.809 149.433 132.712 1.00 193.47 ?  464  PHE A CE1 1 
ATOM   2653 C CE2 . PHE A 1 464 ? 115.979 150.958 132.752 1.00 193.47 ?  464  PHE A CE2 1 
ATOM   2654 C CZ  . PHE A 1 464 ? 116.672 149.939 132.134 1.00 193.47 ?  464  PHE A CZ  1 
ATOM   2655 N N   . VAL A 1 465 ? 118.334 154.523 135.119 1.00 202.93 ?  465  VAL A N   1 
ATOM   2656 C CA  . VAL A 1 465 ? 118.015 155.628 134.229 1.00 202.93 ?  465  VAL A CA  1 
ATOM   2657 C C   . VAL A 1 465 ? 119.267 156.387 133.835 1.00 202.93 ?  465  VAL A C   1 
ATOM   2658 O O   . VAL A 1 465 ? 119.513 156.628 132.651 1.00 202.93 ?  465  VAL A O   1 
ATOM   2659 C CB  . VAL A 1 465 ? 116.972 156.563 134.876 1.00 202.93 ?  465  VAL A CB  1 
ATOM   2660 C CG1 . VAL A 1 465 ? 116.900 157.908 134.169 1.00 202.93 ?  465  VAL A CG1 1 
ATOM   2661 C CG2 . VAL A 1 465 ? 115.612 155.897 134.855 1.00 202.93 ?  465  VAL A CG2 1 
ATOM   2662 N N   . MET A 1 466 ? 120.084 156.739 134.814 1.00 206.60 ?  466  MET A N   1 
ATOM   2663 C CA  . MET A 1 466 ? 121.274 157.510 134.526 1.00 206.60 ?  466  MET A CA  1 
ATOM   2664 C C   . MET A 1 466 ? 122.223 156.731 133.659 1.00 206.60 ?  466  MET A C   1 
ATOM   2665 O O   . MET A 1 466 ? 122.682 157.223 132.645 1.00 206.60 ?  466  MET A O   1 
ATOM   2666 C CB  . MET A 1 466 ? 121.959 157.942 135.806 1.00 206.60 ?  466  MET A CB  1 
ATOM   2667 C CG  . MET A 1 466 ? 121.769 159.410 136.136 1.00 206.60 ?  466  MET A CG  1 
ATOM   2668 S SD  . MET A 1 466 ? 120.035 159.864 136.283 1.00 206.60 ?  466  MET A SD  1 
ATOM   2669 C CE  . MET A 1 466 ? 120.077 161.529 135.630 1.00 206.60 ?  466  MET A CE  1 
ATOM   2670 N N   . LYS A 1 467 ? 122.494 155.493 134.035 1.00 171.12 ?  467  LYS A N   1 
ATOM   2671 C CA  . LYS A 1 467 ? 123.416 154.675 133.273 1.00 171.12 ?  467  LYS A CA  1 
ATOM   2672 C C   . LYS A 1 467 ? 122.868 154.267 131.926 1.00 171.12 ?  467  LYS A C   1 
ATOM   2673 O O   . LYS A 1 467 ? 123.625 153.850 131.082 1.00 171.12 ?  467  LYS A O   1 
ATOM   2674 C CB  . LYS A 1 467 ? 123.868 153.459 134.074 1.00 171.12 ?  467  LYS A CB  1 
ATOM   2675 C CG  . LYS A 1 467 ? 124.853 153.790 135.176 1.00 171.12 ?  467  LYS A CG  1 
ATOM   2676 C CD  . LYS A 1 467 ? 126.276 153.492 134.747 1.00 171.12 ?  467  LYS A CD  1 
ATOM   2677 C CE  . LYS A 1 467 ? 127.276 154.126 135.696 1.00 171.12 ?  467  LYS A CE  1 
ATOM   2678 N NZ  . LYS A 1 467 ? 128.109 155.151 135.010 1.00 171.12 1  467  LYS A NZ  1 
ATOM   2679 N N   . PHE A 1 468 ? 121.565 154.377 131.708 1.00 195.61 ?  468  PHE A N   1 
ATOM   2680 C CA  . PHE A 1 468 ? 121.015 154.089 130.394 1.00 195.61 ?  468  PHE A CA  1 
ATOM   2681 C C   . PHE A 1 468 ? 121.554 155.108 129.424 1.00 195.61 ?  468  PHE A C   1 
ATOM   2682 O O   . PHE A 1 468 ? 122.173 154.747 128.430 1.00 195.61 ?  468  PHE A O   1 
ATOM   2683 C CB  . PHE A 1 468 ? 119.491 154.131 130.397 1.00 195.61 ?  468  PHE A CB  1 
ATOM   2684 C CG  . PHE A 1 468 ? 118.853 153.168 129.446 1.00 195.61 ?  468  PHE A CG  1 
ATOM   2685 C CD1 . PHE A 1 468 ? 118.849 151.813 129.712 1.00 195.61 ?  468  PHE A CD1 1 
ATOM   2686 C CD2 . PHE A 1 468 ? 118.242 153.619 128.292 1.00 195.61 ?  468  PHE A CD2 1 
ATOM   2687 C CE1 . PHE A 1 468 ? 118.260 150.921 128.840 1.00 195.61 ?  468  PHE A CE1 1 
ATOM   2688 C CE2 . PHE A 1 468 ? 117.651 152.734 127.415 1.00 195.61 ?  468  PHE A CE2 1 
ATOM   2689 C CZ  . PHE A 1 468 ? 117.656 151.384 127.692 1.00 195.61 ?  468  PHE A CZ  1 
ATOM   2690 N N   . TRP A 1 469 ? 121.333 156.387 129.717 1.00 191.84 ?  469  TRP A N   1 
ATOM   2691 C CA  . TRP A 1 469 ? 121.792 157.431 128.816 1.00 191.84 ?  469  TRP A CA  1 
ATOM   2692 C C   . TRP A 1 469 ? 123.300 157.528 128.793 1.00 191.84 ?  469  TRP A C   1 
ATOM   2693 O O   . TRP A 1 469 ? 123.879 157.814 127.757 1.00 191.84 ?  469  TRP A O   1 
ATOM   2694 C CB  . TRP A 1 469 ? 121.133 158.801 129.082 1.00 191.84 ?  469  TRP A CB  1 
ATOM   2695 C CG  . TRP A 1 469 ? 121.465 159.499 130.379 1.00 191.84 ?  469  TRP A CG  1 
ATOM   2696 C CD1 . TRP A 1 469 ? 120.707 159.511 131.506 1.00 191.84 ?  469  TRP A CD1 1 
ATOM   2697 C CD2 . TRP A 1 469 ? 122.607 160.333 130.658 1.00 191.84 ?  469  TRP A CD2 1 
ATOM   2698 N NE1 . TRP A 1 469 ? 121.311 160.266 132.478 1.00 191.84 ?  469  TRP A NE1 1 
ATOM   2699 C CE2 . TRP A 1 469 ? 122.479 160.779 131.985 1.00 191.84 ?  469  TRP A CE2 1 
ATOM   2700 C CE3 . TRP A 1 469 ? 123.728 160.730 129.920 1.00 191.84 ?  469  TRP A CE3 1 
ATOM   2701 C CZ2 . TRP A 1 469 ? 123.423 161.603 132.590 1.00 191.84 ?  469  TRP A CZ2 1 
ATOM   2702 C CZ3 . TRP A 1 469 ? 124.669 161.539 130.526 1.00 191.84 ?  469  TRP A CZ3 1 
ATOM   2703 C CH2 . TRP A 1 469 ? 124.509 161.971 131.846 1.00 191.84 ?  469  TRP A CH2 1 
ATOM   2704 N N   . MET A 1 470 ? 123.942 157.281 129.926 1.00 169.44 ?  470  MET A N   1 
ATOM   2705 C CA  . MET A 1 470 ? 125.391 157.320 129.987 1.00 169.44 ?  470  MET A CA  1 
ATOM   2706 C C   . MET A 1 470 ? 125.971 156.285 129.059 1.00 169.44 ?  470  MET A C   1 
ATOM   2707 O O   . MET A 1 470 ? 126.864 156.578 128.282 1.00 169.44 ?  470  MET A O   1 
ATOM   2708 C CB  . MET A 1 470 ? 125.869 157.055 131.399 1.00 169.44 ?  470  MET A CB  1 
ATOM   2709 C CG  . MET A 1 470 ? 125.779 158.251 132.313 1.00 169.44 ?  470  MET A CG  1 
ATOM   2710 S SD  . MET A 1 470 ? 125.914 157.752 134.029 1.00 169.44 ?  470  MET A SD  1 
ATOM   2711 C CE  . MET A 1 470 ? 125.444 159.282 134.806 1.00 169.44 ?  470  MET A CE  1 
ATOM   2712 N N   . SER A 1 471 ? 125.449 155.067 129.121 1.00 148.38 ?  471  SER A N   1 
ATOM   2713 C CA  . SER A 1 471 ? 125.934 154.001 128.263 1.00 148.38 ?  471  SER A CA  1 
ATOM   2714 C C   . SER A 1 471 ? 125.601 154.249 126.804 1.00 148.38 ?  471  SER A C   1 
ATOM   2715 O O   . SER A 1 471 ? 126.366 153.878 125.933 1.00 148.38 ?  471  SER A O   1 
ATOM   2716 C CB  . SER A 1 471 ? 125.360 152.667 128.709 1.00 148.38 ?  471  SER A CB  1 
ATOM   2717 O OG  . SER A 1 471 ? 125.710 152.385 130.048 1.00 148.38 ?  471  SER A OG  1 
ATOM   2718 N N   . ILE A 1 472 ? 124.471 154.882 126.523 1.00 186.70 ?  472  ILE A N   1 
ATOM   2719 C CA  . ILE A 1 472 ? 124.122 155.208 125.146 1.00 186.70 ?  472  ILE A CA  1 
ATOM   2720 C C   . ILE A 1 472 ? 125.157 156.150 124.533 1.00 186.70 ?  472  ILE A C   1 
ATOM   2721 O O   . ILE A 1 472 ? 125.619 155.917 123.420 1.00 186.70 ?  472  ILE A O   1 
ATOM   2722 C CB  . ILE A 1 472 ? 122.652 155.707 125.010 1.00 186.70 ?  472  ILE A CB  1 
ATOM   2723 C CG1 . ILE A 1 472 ? 121.735 154.540 124.659 1.00 186.70 ?  472  ILE A CG1 1 
ATOM   2724 C CG2 . ILE A 1 472 ? 122.486 156.753 123.926 1.00 186.70 ?  472  ILE A CG2 1 
ATOM   2725 C CD1 . ILE A 1 472 ? 120.396 154.572 125.349 1.00 186.70 ?  472  ILE A CD1 1 
ATOM   2726 N N   . VAL A 1 473 ? 125.579 157.172 125.267 1.00 198.17 ?  473  VAL A N   1 
ATOM   2727 C CA  . VAL A 1 473 ? 126.505 158.148 124.701 1.00 198.17 ?  473  VAL A CA  1 
ATOM   2728 C C   . VAL A 1 473 ? 127.982 157.796 124.825 1.00 198.17 ?  473  VAL A C   1 
ATOM   2729 O O   . VAL A 1 473 ? 128.814 158.391 124.139 1.00 198.17 ?  473  VAL A O   1 
ATOM   2730 C CB  . VAL A 1 473 ? 126.248 159.567 125.250 1.00 198.17 ?  473  VAL A CB  1 
ATOM   2731 C CG1 . VAL A 1 473 ? 124.840 160.018 124.905 1.00 198.17 ?  473  VAL A CG1 1 
ATOM   2732 C CG2 . VAL A 1 473 ? 126.474 159.630 126.750 1.00 198.17 ?  473  VAL A CG2 1 
ATOM   2733 N N   . ALA A 1 474 ? 128.310 156.833 125.676 1.00 179.15 ?  474  ALA A N   1 
ATOM   2734 C CA  . ALA A 1 474 ? 129.694 156.419 125.843 1.00 179.15 ?  474  ALA A CA  1 
ATOM   2735 C C   . ALA A 1 474 ? 130.026 155.346 124.834 1.00 179.15 ?  474  ALA A C   1 
ATOM   2736 O O   . ALA A 1 474 ? 131.192 155.074 124.565 1.00 179.15 ?  474  ALA A O   1 
ATOM   2737 C CB  . ALA A 1 474 ? 129.928 155.912 127.242 1.00 179.15 ?  474  ALA A CB  1 
ATOM   2738 N N   . THR A 1 475 ? 129.002 154.727 124.261 1.00 160.89 ?  475  THR A N   1 
ATOM   2739 C CA  . THR A 1 475 ? 129.235 153.733 123.224 1.00 160.89 ?  475  THR A CA  1 
ATOM   2740 C C   . THR A 1 475 ? 129.211 154.436 121.881 1.00 160.89 ?  475  THR A C   1 
ATOM   2741 O O   . THR A 1 475 ? 129.441 153.813 120.849 1.00 160.89 ?  475  THR A O   1 
ATOM   2742 C CB  . THR A 1 475 ? 128.204 152.601 123.266 1.00 160.89 ?  475  THR A CB  1 
ATOM   2743 O OG1 . THR A 1 475 ? 126.888 153.154 123.359 1.00 160.89 ?  475  THR A OG1 1 
ATOM   2744 C CG2 . THR A 1 475 ? 128.455 151.708 124.459 1.00 160.89 ?  475  THR A CG2 1 
ATOM   2745 N N   . THR A 1 476 ? 128.946 155.737 121.891 1.00 196.92 ?  476  THR A N   1 
ATOM   2746 C CA  . THR A 1 476 ? 128.918 156.514 120.662 1.00 196.92 ?  476  THR A CA  1 
ATOM   2747 C C   . THR A 1 476 ? 130.240 157.263 120.573 1.00 196.92 ?  476  THR A C   1 
ATOM   2748 O O   . THR A 1 476 ? 130.632 157.749 119.512 1.00 196.92 ?  476  THR A O   1 
ATOM   2749 C CB  . THR A 1 476 ? 127.692 157.443 120.676 1.00 196.92 ?  476  THR A CB  1 
ATOM   2750 O OG1 . THR A 1 476 ? 126.522 156.645 120.874 1.00 196.92 ?  476  THR A OG1 1 
ATOM   2751 C CG2 . THR A 1 476 ? 127.537 158.214 119.378 1.00 196.92 ?  476  THR A CG2 1 
ATOM   2752 N N   . MET A 1 477 ? 130.967 157.315 121.679 1.00 192.79 ?  477  MET A N   1 
ATOM   2753 C CA  . MET A 1 477 ? 132.255 157.998 121.703 1.00 192.79 ?  477  MET A CA  1 
ATOM   2754 C C   . MET A 1 477 ? 133.249 157.363 120.740 1.00 192.79 ?  477  MET A C   1 
ATOM   2755 O O   . MET A 1 477 ? 133.225 156.149 120.536 1.00 192.79 ?  477  MET A O   1 
ATOM   2756 C CB  . MET A 1 477 ? 132.811 157.980 123.125 1.00 192.79 ?  477  MET A CB  1 
ATOM   2757 C CG  . MET A 1 477 ? 132.374 159.151 123.982 1.00 192.79 ?  477  MET A CG  1 
ATOM   2758 S SD  . MET A 1 477 ? 133.128 159.118 125.618 1.00 192.79 ?  477  MET A SD  1 
ATOM   2759 C CE  . MET A 1 477 ? 133.528 157.384 125.785 1.00 192.79 ?  477  MET A CE  1 
ATOM   2760 N N   . PRO A 1 478 ? 134.142 158.173 120.140 1.00 211.25 ?  478  PRO A N   1 
ATOM   2761 C CA  . PRO A 1 478 ? 135.139 157.662 119.183 1.00 211.25 ?  478  PRO A CA  1 
ATOM   2762 C C   . PRO A 1 478 ? 136.315 156.921 119.808 1.00 211.25 ?  478  PRO A C   1 
ATOM   2763 O O   . PRO A 1 478 ? 137.456 157.195 119.449 1.00 211.25 ?  478  PRO A O   1 
ATOM   2764 C CB  . PRO A 1 478 ? 135.650 158.933 118.509 1.00 211.25 ?  478  PRO A CB  1 
ATOM   2765 C CG  . PRO A 1 478 ? 135.413 160.012 119.501 1.00 211.25 ?  478  PRO A CG  1 
ATOM   2766 C CD  . PRO A 1 478 ? 134.136 159.644 120.191 1.00 211.25 ?  478  PRO A CD  1 
ATOM   2767 N N   . ILE A 1 479 ? 136.052 156.000 120.724 1.00 201.13 ?  479  ILE A N   1 
ATOM   2768 C CA  . ILE A 1 479 ? 137.099 155.243 121.382 1.00 201.13 ?  479  ILE A CA  1 
ATOM   2769 C C   . ILE A 1 479 ? 136.712 153.791 121.149 1.00 201.13 ?  479  ILE A C   1 
ATOM   2770 O O   . ILE A 1 479 ? 135.609 153.530 120.689 1.00 201.13 ?  479  ILE A O   1 
ATOM   2771 C CB  . ILE A 1 479 ? 137.148 155.588 122.897 1.00 201.13 ?  479  ILE A CB  1 
ATOM   2772 C CG1 . ILE A 1 479 ? 135.970 154.976 123.653 1.00 201.13 ?  479  ILE A CG1 1 
ATOM   2773 C CG2 . ILE A 1 479 ? 137.164 157.089 123.135 1.00 201.13 ?  479  ILE A CG2 1 
ATOM   2774 C CD1 . ILE A 1 479 ? 136.378 154.351 124.967 1.00 201.13 ?  479  ILE A CD1 1 
ATOM   2775 N N   . PRO A 1 480 ? 137.621 152.833 121.400 1.00 227.50 ?  480  PRO A N   1 
ATOM   2776 C CA  . PRO A 1 480 ? 137.184 151.437 121.291 1.00 227.50 ?  480  PRO A CA  1 
ATOM   2777 C C   . PRO A 1 480 ? 136.179 151.143 122.393 1.00 227.50 ?  480  PRO A C   1 
ATOM   2778 O O   . PRO A 1 480 ? 136.564 151.141 123.558 1.00 227.50 ?  480  PRO A O   1 
ATOM   2779 C CB  . PRO A 1 480 ? 138.456 150.642 121.559 1.00 227.50 ?  480  PRO A CB  1 
ATOM   2780 C CG  . PRO A 1 480 ? 139.571 151.570 121.306 1.00 227.50 ?  480  PRO A CG  1 
ATOM   2781 C CD  . PRO A 1 480 ? 139.071 152.944 121.616 1.00 227.50 ?  480  PRO A CD  1 
ATOM   2782 N N   . CYS A 1 481 ? 134.920 150.907 122.050 1.00 191.72 ?  481  CYS A N   1 
ATOM   2783 C CA  . CYS A 1 481 ? 133.898 150.700 123.066 1.00 191.72 ?  481  CYS A CA  1 
ATOM   2784 C C   . CYS A 1 481 ? 132.950 149.584 122.699 1.00 191.72 ?  481  CYS A C   1 
ATOM   2785 O O   . CYS A 1 481 ? 132.548 149.469 121.556 1.00 191.72 ?  481  CYS A O   1 
ATOM   2786 C CB  . CYS A 1 481 ? 133.098 151.985 123.285 1.00 191.72 ?  481  CYS A CB  1 
ATOM   2787 S SG  . CYS A 1 481 ? 132.628 152.857 121.777 1.00 191.72 ?  481  CYS A SG  1 
ATOM   2788 N N   . GLY A 1 482 ? 132.575 148.765 123.669 1.00 186.76 ?  482  GLY A N   1 
ATOM   2789 C CA  . GLY A 1 482 ? 131.630 147.698 123.414 1.00 186.76 ?  482  GLY A CA  1 
ATOM   2790 C C   . GLY A 1 482 ? 130.319 147.950 124.111 1.00 186.76 ?  482  GLY A C   1 
ATOM   2791 O O   . GLY A 1 482 ? 130.196 148.903 124.874 1.00 186.76 ?  482  GLY A O   1 
ATOM   2792 N N   . GLY A 1 483 ? 129.337 147.096 123.867 1.00 205.56 ?  483  GLY A N   1 
ATOM   2793 C CA  . GLY A 1 483 ? 128.028 147.286 124.458 1.00 205.56 ?  483  GLY A CA  1 
ATOM   2794 C C   . GLY A 1 483 ? 127.612 146.296 125.523 1.00 205.56 ?  483  GLY A C   1 
ATOM   2795 O O   . GLY A 1 483 ? 126.782 146.636 126.342 1.00 205.56 ?  483  GLY A O   1 
ATOM   2796 N N   . PHE A 1 484 ? 128.175 145.091 125.526 1.00 180.54 ?  484  PHE A N   1 
ATOM   2797 C CA  . PHE A 1 484 ? 127.778 144.056 126.484 1.00 180.54 ?  484  PHE A CA  1 
ATOM   2798 C C   . PHE A 1 484 ? 127.794 144.548 127.901 1.00 180.54 ?  484  PHE A C   1 
ATOM   2799 O O   . PHE A 1 484 ? 126.760 144.620 128.523 1.00 180.54 ?  484  PHE A O   1 
ATOM   2800 C CB  . PHE A 1 484 ? 128.716 142.864 126.417 1.00 180.54 ?  484  PHE A CB  1 
ATOM   2801 C CG  . PHE A 1 484 ? 128.122 141.572 126.888 1.00 180.54 ?  484  PHE A CG  1 
ATOM   2802 C CD1 . PHE A 1 484 ? 128.206 141.195 128.218 1.00 180.54 ?  484  PHE A CD1 1 
ATOM   2803 C CD2 . PHE A 1 484 ? 127.522 140.712 125.992 1.00 180.54 ?  484  PHE A CD2 1 
ATOM   2804 C CE1 . PHE A 1 484 ? 127.683 139.995 128.645 1.00 180.54 ?  484  PHE A CE1 1 
ATOM   2805 C CE2 . PHE A 1 484 ? 126.994 139.513 126.415 1.00 180.54 ?  484  PHE A CE2 1 
ATOM   2806 C CZ  . PHE A 1 484 ? 127.073 139.154 127.744 1.00 180.54 ?  484  PHE A CZ  1 
ATOM   2807 N N   . MET A 1 485 ? 128.973 144.839 128.435 1.00 207.53 ?  485  MET A N   1 
ATOM   2808 C CA  . MET A 1 485 ? 129.075 145.235 129.837 1.00 207.53 ?  485  MET A CA  1 
ATOM   2809 C C   . MET A 1 485 ? 128.193 146.438 130.209 1.00 207.53 ?  485  MET A C   1 
ATOM   2810 O O   . MET A 1 485 ? 127.525 146.387 131.229 1.00 207.53 ?  485  MET A O   1 
ATOM   2811 C CB  . MET A 1 485 ? 130.533 145.449 130.246 1.00 207.53 ?  485  MET A CB  1 
ATOM   2812 C CG  . MET A 1 485 ? 131.217 144.187 130.736 1.00 207.53 ?  485  MET A CG  1 
ATOM   2813 S SD  . MET A 1 485 ? 130.703 143.767 132.409 1.00 207.53 ?  485  MET A SD  1 
ATOM   2814 C CE  . MET A 1 485 ? 131.382 145.157 133.310 1.00 207.53 ?  485  MET A CE  1 
ATOM   2815 N N   . PRO A 1 486 ? 128.194 147.539 129.407 1.00 177.21 ?  486  PRO A N   1 
ATOM   2816 C CA  . PRO A 1 486 ? 127.260 148.600 129.795 1.00 177.21 ?  486  PRO A CA  1 
ATOM   2817 C C   . PRO A 1 486 ? 125.825 148.097 129.966 1.00 177.21 ?  486  PRO A C   1 
ATOM   2818 O O   . PRO A 1 486 ? 125.209 148.395 130.978 1.00 177.21 ?  486  PRO A O   1 
ATOM   2819 C CB  . PRO A 1 486 ? 127.344 149.558 128.620 1.00 177.21 ?  486  PRO A CB  1 
ATOM   2820 C CG  . PRO A 1 486 ? 128.740 149.442 128.151 1.00 177.21 ?  486  PRO A CG  1 
ATOM   2821 C CD  . PRO A 1 486 ? 129.170 148.032 128.413 1.00 177.21 ?  486  PRO A CD  1 
ATOM   2822 N N   . VAL A 1 487 ? 125.310 147.330 129.014 1.00 174.21 ?  487  VAL A N   1 
ATOM   2823 C CA  . VAL A 1 487 ? 123.954 146.790 129.091 1.00 174.21 ?  487  VAL A CA  1 
ATOM   2824 C C   . VAL A 1 487 ? 123.828 145.693 130.148 1.00 174.21 ?  487  VAL A C   1 
ATOM   2825 O O   . VAL A 1 487 ? 122.756 145.472 130.701 1.00 174.21 ?  487  VAL A O   1 
ATOM   2826 C CB  . VAL A 1 487 ? 123.500 146.320 127.690 1.00 174.21 ?  487  VAL A CB  1 
ATOM   2827 C CG1 . VAL A 1 487 ? 122.046 145.925 127.683 1.00 174.21 ?  487  VAL A CG1 1 
ATOM   2828 C CG2 . VAL A 1 487 ? 123.686 147.441 126.691 1.00 174.21 ?  487  VAL A CG2 1 
ATOM   2829 N N   . PHE A 1 488 ? 124.918 145.015 130.459 1.00 179.03 ?  488  PHE A N   1 
ATOM   2830 C CA  . PHE A 1 488 ? 124.914 143.995 131.497 1.00 179.03 ?  488  PHE A CA  1 
ATOM   2831 C C   . PHE A 1 488 ? 124.632 144.643 132.838 1.00 179.03 ?  488  PHE A C   1 
ATOM   2832 O O   . PHE A 1 488 ? 123.804 144.159 133.593 1.00 179.03 ?  488  PHE A O   1 
ATOM   2833 C CB  . PHE A 1 488 ? 126.284 143.338 131.533 1.00 179.03 ?  488  PHE A CB  1 
ATOM   2834 C CG  . PHE A 1 488 ? 126.319 142.000 132.187 1.00 179.03 ?  488  PHE A CG  1 
ATOM   2835 C CD1 . PHE A 1 488 ? 125.895 140.879 131.509 1.00 179.03 ?  488  PHE A CD1 1 
ATOM   2836 C CD2 . PHE A 1 488 ? 126.819 141.857 133.467 1.00 179.03 ?  488  PHE A CD2 1 
ATOM   2837 C CE1 . PHE A 1 488 ? 125.954 139.638 132.099 1.00 179.03 ?  488  PHE A CE1 1 
ATOM   2838 C CE2 . PHE A 1 488 ? 126.877 140.620 134.066 1.00 179.03 ?  488  PHE A CE2 1 
ATOM   2839 C CZ  . PHE A 1 488 ? 126.443 139.509 133.383 1.00 179.03 ?  488  PHE A CZ  1 
ATOM   2840 N N   . VAL A 1 489 ? 125.311 145.749 133.135 1.00 173.69 ?  489  VAL A N   1 
ATOM   2841 C CA  . VAL A 1 489 ? 125.078 146.449 134.394 1.00 173.69 ?  489  VAL A CA  1 
ATOM   2842 C C   . VAL A 1 489 ? 123.682 147.045 134.433 1.00 173.69 ?  489  VAL A C   1 
ATOM   2843 O O   . VAL A 1 489 ? 123.082 147.145 135.497 1.00 173.69 ?  489  VAL A O   1 
ATOM   2844 C CB  . VAL A 1 489 ? 126.176 147.494 134.752 1.00 173.69 ?  489  VAL A CB  1 
ATOM   2845 C CG1 . VAL A 1 489 ? 127.559 147.021 134.363 1.00 173.69 ?  489  VAL A CG1 1 
ATOM   2846 C CG2 . VAL A 1 489 ? 125.890 148.882 134.200 1.00 173.69 ?  489  VAL A CG2 1 
ATOM   2847 N N   . LEU A 1 490 ? 123.143 147.395 133.272 1.00 175.84 ?  490  LEU A N   1 
ATOM   2848 C CA  . LEU A 1 490 ? 121.816 147.967 133.207 1.00 175.84 ?  490  LEU A CA  1 
ATOM   2849 C C   . LEU A 1 490 ? 120.780 146.918 133.504 1.00 175.84 ?  490  LEU A C   1 
ATOM   2850 O O   . LEU A 1 490 ? 119.827 147.168 134.219 1.00 175.84 ?  490  LEU A O   1 
ATOM   2851 C CB  . LEU A 1 490 ? 121.588 148.555 131.826 1.00 175.84 ?  490  LEU A CB  1 
ATOM   2852 C CG  . LEU A 1 490 ? 122.269 149.902 131.659 1.00 175.84 ?  490  LEU A CG  1 
ATOM   2853 C CD1 . LEU A 1 490 ? 122.208 150.372 130.219 1.00 175.84 ?  490  LEU A CD1 1 
ATOM   2854 C CD2 . LEU A 1 490 ? 121.601 150.878 132.599 1.00 175.84 ?  490  LEU A CD2 1 
ATOM   2855 N N   . GLY A 1 491 ? 120.970 145.726 132.968 1.00 201.49 ?  491  GLY A N   1 
ATOM   2856 C CA  . GLY A 1 491 ? 120.036 144.659 133.209 1.00 201.49 ?  491  GLY A CA  1 
ATOM   2857 C C   . GLY A 1 491 ? 120.118 144.168 134.617 1.00 201.49 ?  491  GLY A C   1 
ATOM   2858 O O   . GLY A 1 491 ? 119.117 143.781 135.193 1.00 201.49 ?  491  GLY A O   1 
ATOM   2859 N N   . ALA A 1 492 ? 121.311 144.175 135.184 1.00 210.27 ?  492  ALA A N   1 
ATOM   2860 C CA  . ALA A 1 492 ? 121.466 143.773 136.561 1.00 210.27 ?  492  ALA A CA  1 
ATOM   2861 C C   . ALA A 1 492 ? 120.715 144.746 137.435 1.00 210.27 ?  492  ALA A C   1 
ATOM   2862 O O   . ALA A 1 492 ? 120.054 144.341 138.371 1.00 210.27 ?  492  ALA A O   1 
ATOM   2863 C CB  . ALA A 1 492 ? 122.931 143.720 136.926 1.00 210.27 ?  492  ALA A CB  1 
ATOM   2864 N N   . ALA A 1 493 ? 120.787 146.032 137.120 1.00 201.74 ?  493  ALA A N   1 
ATOM   2865 C CA  . ALA A 1 493 ? 120.041 147.030 137.865 1.00 201.74 ?  493  ALA A CA  1 
ATOM   2866 C C   . ALA A 1 493 ? 118.552 146.832 137.726 1.00 201.74 ?  493  ALA A C   1 
ATOM   2867 O O   . ALA A 1 493 ? 117.830 146.869 138.706 1.00 201.74 ?  493  ALA A O   1 
ATOM   2868 C CB  . ALA A 1 493 ? 120.414 148.413 137.397 1.00 201.74 ?  493  ALA A CB  1 
ATOM   2869 N N   . PHE A 1 494 ? 118.087 146.623 136.506 1.00 215.80 ?  494  PHE A N   1 
ATOM   2870 C CA  . PHE A 1 494 ? 116.672 146.407 136.281 1.00 215.80 ?  494  PHE A CA  1 
ATOM   2871 C C   . PHE A 1 494 ? 116.191 145.175 137.020 1.00 215.80 ?  494  PHE A C   1 
ATOM   2872 O O   . PHE A 1 494 ? 115.173 145.218 137.697 1.00 215.80 ?  494  PHE A O   1 
ATOM   2873 C CB  . PHE A 1 494 ? 116.374 146.275 134.793 1.00 215.80 ?  494  PHE A CB  1 
ATOM   2874 C CG  . PHE A 1 494 ? 114.917 146.145 134.492 1.00 215.80 ?  494  PHE A CG  1 
ATOM   2875 C CD1 . PHE A 1 494 ? 114.075 147.228 134.649 1.00 215.80 ?  494  PHE A CD1 1 
ATOM   2876 C CD2 . PHE A 1 494 ? 114.382 144.936 134.084 1.00 215.80 ?  494  PHE A CD2 1 
ATOM   2877 C CE1 . PHE A 1 494 ? 112.728 147.115 134.392 1.00 215.80 ?  494  PHE A CE1 1 
ATOM   2878 C CE2 . PHE A 1 494 ? 113.037 144.814 133.825 1.00 215.80 ?  494  PHE A CE2 1 
ATOM   2879 C CZ  . PHE A 1 494 ? 112.209 145.905 133.981 1.00 215.80 ?  494  PHE A CZ  1 
ATOM   2880 N N   . GLY A 1 495 ? 116.923 144.078 136.899 1.00 214.99 ?  495  GLY A N   1 
ATOM   2881 C CA  . GLY A 1 495 ? 116.542 142.856 137.564 1.00 214.99 ?  495  GLY A CA  1 
ATOM   2882 C C   . GLY A 1 495 ? 116.531 142.999 139.058 1.00 214.99 ?  495  GLY A C   1 
ATOM   2883 O O   . GLY A 1 495 ? 115.636 142.502 139.713 1.00 214.99 ?  495  GLY A O   1 
ATOM   2884 N N   . ARG A 1 496 ? 117.519 143.686 139.607 1.00 225.16 ?  496  ARG A N   1 
ATOM   2885 C CA  . ARG A 1 496 ? 117.564 143.909 141.037 1.00 225.16 ?  496  ARG A CA  1 
ATOM   2886 C C   . ARG A 1 496 ? 116.373 144.715 141.474 1.00 225.16 ?  496  ARG A C   1 
ATOM   2887 O O   . ARG A 1 496 ? 115.736 144.372 142.445 1.00 225.16 ?  496  ARG A O   1 
ATOM   2888 C CB  . ARG A 1 496 ? 118.838 144.629 141.436 1.00 225.16 ?  496  ARG A CB  1 
ATOM   2889 C CG  . ARG A 1 496 ? 119.072 144.675 142.926 1.00 225.16 ?  496  ARG A CG  1 
ATOM   2890 C CD  . ARG A 1 496 ? 119.754 143.414 143.400 1.00 225.16 ?  496  ARG A CD  1 
ATOM   2891 N NE  . ARG A 1 496 ? 119.691 143.297 144.845 1.00 225.16 ?  496  ARG A NE  1 
ATOM   2892 C CZ  . ARG A 1 496 ? 120.556 142.611 145.576 1.00 225.16 ?  496  ARG A CZ  1 
ATOM   2893 N NH1 . ARG A 1 496 ? 121.563 141.982 145.001 1.00 225.16 1  496  ARG A NH1 1 
ATOM   2894 N NH2 . ARG A 1 496 ? 120.416 142.566 146.886 1.00 225.16 ?  496  ARG A NH2 1 
ATOM   2895 N N   . LEU A 1 497 ? 116.055 145.778 140.754 1.00 207.47 ?  497  LEU A N   1 
ATOM   2896 C CA  . LEU A 1 497 ? 114.883 146.579 141.072 1.00 207.47 ?  497  LEU A CA  1 
ATOM   2897 C C   . LEU A 1 497 ? 113.650 145.701 141.133 1.00 207.47 ?  497  LEU A C   1 
ATOM   2898 O O   . LEU A 1 497 ? 112.904 145.764 142.097 1.00 207.47 ?  497  LEU A O   1 
ATOM   2899 C CB  . LEU A 1 497 ? 114.719 147.700 140.047 1.00 207.47 ?  497  LEU A CB  1 
ATOM   2900 C CG  . LEU A 1 497 ? 113.393 148.427 139.871 1.00 207.47 ?  497  LEU A CG  1 
ATOM   2901 C CD1 . LEU A 1 497 ? 113.518 149.832 140.423 1.00 207.47 ?  497  LEU A CD1 1 
ATOM   2902 C CD2 . LEU A 1 497 ? 113.025 148.462 138.397 1.00 207.47 ?  497  LEU A CD2 1 
ATOM   2903 N N   . VAL A 1 498 ? 113.447 144.858 140.130 1.00 210.38 ?  498  VAL A N   1 
ATOM   2904 C CA  . VAL A 1 498 ? 112.315 143.945 140.136 1.00 210.38 ?  498  VAL A CA  1 
ATOM   2905 C C   . VAL A 1 498 ? 112.366 143.036 141.352 1.00 210.38 ?  498  VAL A C   1 
ATOM   2906 O O   . VAL A 1 498 ? 111.389 142.926 142.068 1.00 210.38 ?  498  VAL A O   1 
ATOM   2907 C CB  . VAL A 1 498 ? 112.231 143.130 138.829 1.00 210.38 ?  498  VAL A CB  1 
ATOM   2908 C CG1 . VAL A 1 498 ? 111.118 142.094 138.898 1.00 210.38 ?  498  VAL A CG1 1 
ATOM   2909 C CG2 . VAL A 1 498 ? 112.004 144.059 137.650 1.00 210.38 ?  498  VAL A CG2 1 
ATOM   2910 N N   . GLY A 1 499 ? 113.507 142.415 141.614 1.00 215.52 ?  499  GLY A N   1 
ATOM   2911 C CA  . GLY A 1 499 ? 113.653 141.558 142.776 1.00 215.52 ?  499  GLY A CA  1 
ATOM   2912 C C   . GLY A 1 499 ? 113.487 142.214 144.129 1.00 215.52 ?  499  GLY A C   1 
ATOM   2913 O O   . GLY A 1 499 ? 113.006 141.583 145.055 1.00 215.52 ?  499  GLY A O   1 
ATOM   2914 N N   . GLU A 1 500 ? 113.885 143.472 144.262 1.00 232.84 ?  500  GLU A N   1 
ATOM   2915 C CA  . GLU A 1 500 ? 113.713 144.191 145.515 1.00 232.84 ?  500  GLU A CA  1 
ATOM   2916 C C   . GLU A 1 500 ? 112.270 144.593 145.682 1.00 232.84 ?  500  GLU A C   1 
ATOM   2917 O O   . GLU A 1 500 ? 111.772 144.659 146.798 1.00 232.84 ?  500  GLU A O   1 
ATOM   2918 C CB  . GLU A 1 500 ? 114.618 145.423 145.588 1.00 232.84 ?  500  GLU A CB  1 
ATOM   2919 C CG  . GLU A 1 500 ? 116.111 145.141 145.563 1.00 232.84 ?  500  GLU A CG  1 
ATOM   2920 C CD  . GLU A 1 500 ? 116.657 144.616 146.872 1.00 232.84 ?  500  GLU A CD  1 
ATOM   2921 O OE1 . GLU A 1 500 ? 115.953 144.669 147.894 1.00 232.84 ?  500  GLU A OE1 1 
ATOM   2922 O OE2 . GLU A 1 500 ? 117.808 144.144 146.880 1.00 232.84 -1 500  GLU A OE2 1 
ATOM   2923 N N   . ILE A 1 501 ? 111.586 144.865 144.582 1.00 224.81 ?  501  ILE A N   1 
ATOM   2924 C CA  . ILE A 1 501 ? 110.168 145.169 144.657 1.00 224.81 ?  501  ILE A CA  1 
ATOM   2925 C C   . ILE A 1 501 ? 109.461 143.876 145.010 1.00 224.81 ?  501  ILE A C   1 
ATOM   2926 O O   . ILE A 1 501 ? 108.565 143.870 145.836 1.00 224.81 ?  501  ILE A O   1 
ATOM   2927 C CB  . ILE A 1 501 ? 109.650 145.771 143.334 1.00 224.81 ?  501  ILE A CB  1 
ATOM   2928 C CG1 . ILE A 1 501 ? 110.079 147.231 143.220 1.00 224.81 ?  501  ILE A CG1 1 
ATOM   2929 C CG2 . ILE A 1 501 ? 108.136 145.679 143.217 1.00 224.81 ?  501  ILE A CG2 1 
ATOM   2930 C CD1 . ILE A 1 501 ? 109.948 147.788 141.821 1.00 224.81 ?  501  ILE A CD1 1 
ATOM   2931 N N   . MET A 1 502 ? 109.902 142.762 144.437 1.00 231.93 ?  502  MET A N   1 
ATOM   2932 C CA  . MET A 1 502 ? 109.315 141.469 144.750 1.00 231.93 ?  502  MET A CA  1 
ATOM   2933 C C   . MET A 1 502 ? 109.531 141.114 146.206 1.00 231.93 ?  502  MET A C   1 
ATOM   2934 O O   . MET A 1 502 ? 108.719 140.427 146.797 1.00 231.93 ?  502  MET A O   1 
ATOM   2935 C CB  . MET A 1 502 ? 109.905 140.382 143.858 1.00 231.93 ?  502  MET A CB  1 
ATOM   2936 C CG  . MET A 1 502 ? 109.302 140.306 142.469 1.00 231.93 ?  502  MET A CG  1 
ATOM   2937 S SD  . MET A 1 502 ? 107.607 139.704 142.473 1.00 231.93 ?  502  MET A SD  1 
ATOM   2938 C CE  . MET A 1 502 ? 107.860 137.938 142.617 1.00 231.93 ?  502  MET A CE  1 
ATOM   2939 N N   . ALA A 1 503 ? 110.621 141.590 146.791 1.00 224.20 ?  503  ALA A N   1 
ATOM   2940 C CA  . ALA A 1 503 ? 110.900 141.328 148.191 1.00 224.20 ?  503  ALA A CA  1 
ATOM   2941 C C   . ALA A 1 503 ? 110.046 142.199 149.079 1.00 224.20 ?  503  ALA A C   1 
ATOM   2942 O O   . ALA A 1 503 ? 109.761 141.836 150.207 1.00 224.20 ?  503  ALA A O   1 
ATOM   2943 C CB  . ALA A 1 503 ? 112.364 141.558 148.478 1.00 224.20 ?  503  ALA A CB  1 
ATOM   2944 N N   . MET A 1 504 ? 109.641 143.358 148.587 1.00 242.39 ?  504  MET A N   1 
ATOM   2945 C CA  . MET A 1 504 ? 108.748 144.212 149.352 1.00 242.39 ?  504  MET A CA  1 
ATOM   2946 C C   . MET A 1 504 ? 107.360 143.618 149.294 1.00 242.39 ?  504  MET A C   1 
ATOM   2947 O O   . MET A 1 504 ? 106.650 143.599 150.293 1.00 242.39 ?  504  MET A O   1 
ATOM   2948 C CB  . MET A 1 504 ? 108.703 145.604 148.743 1.00 242.39 ?  504  MET A CB  1 
ATOM   2949 C CG  . MET A 1 504 ? 109.837 146.516 149.146 1.00 242.39 ?  504  MET A CG  1 
ATOM   2950 S SD  . MET A 1 504 ? 109.974 147.906 148.012 1.00 242.39 ?  504  MET A SD  1 
ATOM   2951 C CE  . MET A 1 504 ? 108.441 147.738 147.104 1.00 242.39 ?  504  MET A CE  1 
ATOM   2952 N N   . LEU A 1 505 ? 106.967 143.133 148.123 1.00 248.74 ?  505  LEU A N   1 
ATOM   2953 C CA  . LEU A 1 505 ? 105.648 142.535 147.955 1.00 248.74 ?  505  LEU A CA  1 
ATOM   2954 C C   . LEU A 1 505 ? 105.553 141.246 148.734 1.00 248.74 ?  505  LEU A C   1 
ATOM   2955 O O   . LEU A 1 505 ? 104.482 140.888 149.212 1.00 248.74 ?  505  LEU A O   1 
ATOM   2956 C CB  . LEU A 1 505 ? 105.378 142.249 146.483 1.00 248.74 ?  505  LEU A CB  1 
ATOM   2957 C CG  . LEU A 1 505 ? 105.317 143.429 145.521 1.00 248.74 ?  505  LEU A CG  1 
ATOM   2958 C CD1 . LEU A 1 505 ? 105.243 142.922 144.090 1.00 248.74 ?  505  LEU A CD1 1 
ATOM   2959 C CD2 . LEU A 1 505 ? 104.144 144.336 145.847 1.00 248.74 ?  505  LEU A CD2 1 
ATOM   2960 N N   . PHE A 1 506 ? 106.665 140.538 148.852 1.00 246.98 ?  506  PHE A N   1 
ATOM   2961 C CA  . PHE A 1 506 ? 106.682 139.275 149.576 1.00 246.98 ?  506  PHE A CA  1 
ATOM   2962 C C   . PHE A 1 506 ? 107.785 139.280 150.610 1.00 246.98 ?  506  PHE A C   1 
ATOM   2963 O O   . PHE A 1 506 ? 108.839 138.690 150.389 1.00 246.98 ?  506  PHE A O   1 
ATOM   2964 C CB  . PHE A 1 506 ? 106.905 138.117 148.612 1.00 246.98 ?  506  PHE A CB  1 
ATOM   2965 C CG  . PHE A 1 506 ? 105.863 138.016 147.544 1.00 246.98 ?  506  PHE A CG  1 
ATOM   2966 C CD1 . PHE A 1 506 ? 104.617 137.495 147.831 1.00 246.98 ?  506  PHE A CD1 1 
ATOM   2967 C CD2 . PHE A 1 506 ? 106.122 138.456 146.257 1.00 246.98 ?  506  PHE A CD2 1 
ATOM   2968 C CE1 . PHE A 1 506 ? 103.647 137.408 146.854 1.00 246.98 ?  506  PHE A CE1 1 
ATOM   2969 C CE2 . PHE A 1 506 ? 105.156 138.376 145.278 1.00 246.98 ?  506  PHE A CE2 1 
ATOM   2970 C CZ  . PHE A 1 506 ? 103.918 137.847 145.574 1.00 246.98 ?  506  PHE A CZ  1 
ATOM   2971 N N   . PRO A 1 507 ? 107.572 139.967 151.787 1.00 253.49 ?  507  PRO A N   1 
ATOM   2972 C CA  . PRO A 1 507 ? 108.724 139.959 152.699 1.00 253.49 ?  507  PRO A CA  1 
ATOM   2973 C C   . PRO A 1 507 ? 108.849 138.657 153.442 1.00 253.49 ?  507  PRO A C   1 
ATOM   2974 O O   . PRO A 1 507 ? 109.802 138.471 154.194 1.00 253.49 ?  507  PRO A O   1 
ATOM   2975 C CB  . PRO A 1 507 ? 108.401 141.082 153.693 1.00 253.49 ?  507  PRO A CB  1 
ATOM   2976 C CG  . PRO A 1 507 ? 107.210 141.793 153.159 1.00 253.49 ?  507  PRO A CG  1 
ATOM   2977 C CD  . PRO A 1 507 ? 106.469 140.747 152.406 1.00 253.49 ?  507  PRO A CD  1 
ATOM   2978 N N   . ASP A 1 508 ? 107.896 137.759 153.239 1.00 263.43 ?  508  ASP A N   1 
ATOM   2979 C CA  . ASP A 1 508 ? 107.899 136.483 153.931 1.00 263.43 ?  508  ASP A CA  1 
ATOM   2980 C C   . ASP A 1 508 ? 108.314 135.427 152.945 1.00 263.43 ?  508  ASP A C   1 
ATOM   2981 O O   . ASP A 1 508 ? 108.697 134.325 153.326 1.00 263.43 ?  508  ASP A O   1 
ATOM   2982 C CB  . ASP A 1 508 ? 106.493 136.197 154.426 1.00 263.43 ?  508  ASP A CB  1 
ATOM   2983 C CG  . ASP A 1 508 ? 105.458 137.093 153.771 1.00 263.43 ?  508  ASP A CG  1 
ATOM   2984 O OD1 . ASP A 1 508 ? 105.170 136.903 152.569 1.00 263.43 ?  508  ASP A OD1 1 
ATOM   2985 O OD2 . ASP A 1 508 ? 104.939 137.998 154.457 1.00 263.43 -1 508  ASP A OD2 1 
ATOM   2986 N N   . GLY A 1 509 ? 108.243 135.762 151.666 1.00 262.92 ?  509  GLY A N   1 
ATOM   2987 C CA  . GLY A 1 509 ? 108.573 134.799 150.640 1.00 262.92 ?  509  GLY A CA  1 
ATOM   2988 C C   . GLY A 1 509 ? 107.288 134.274 150.058 1.00 262.92 ?  509  GLY A C   1 
ATOM   2989 O O   . GLY A 1 509 ? 106.214 134.518 150.598 1.00 262.92 ?  509  GLY A O   1 
ATOM   2990 N N   . ILE A 1 510 ? 107.387 133.561 148.941 1.00 274.31 ?  510  ILE A N   1 
ATOM   2991 C CA  . ILE A 1 510 ? 106.205 132.980 148.315 1.00 274.31 ?  510  ILE A CA  1 
ATOM   2992 C C   . ILE A 1 510 ? 106.159 131.482 148.519 1.00 274.31 ?  510  ILE A C   1 
ATOM   2993 O O   . ILE A 1 510 ? 107.134 130.791 148.259 1.00 274.31 ?  510  ILE A O   1 
ATOM   2994 C CB  . ILE A 1 510 ? 106.165 133.228 146.801 1.00 274.31 ?  510  ILE A CB  1 
ATOM   2995 C CG1 . ILE A 1 510 ? 107.143 134.315 146.385 1.00 274.31 ?  510  ILE A CG1 1 
ATOM   2996 C CG2 . ILE A 1 510 ? 104.766 133.619 146.365 1.00 274.31 ?  510  ILE A CG2 1 
ATOM   2997 C CD1 . ILE A 1 510 ? 106.755 134.945 145.071 1.00 274.31 ?  510  ILE A CD1 1 
ATOM   2998 N N   . LEU A 1 511 ? 105.026 130.973 148.979 1.00 278.35 ?  511  LEU A N   1 
ATOM   2999 C CA  . LEU A 1 511 ? 104.884 129.535 149.122 1.00 278.35 ?  511  LEU A CA  1 
ATOM   3000 C C   . LEU A 1 511 ? 104.291 128.961 147.851 1.00 278.35 ?  511  LEU A C   1 
ATOM   3001 O O   . LEU A 1 511 ? 103.203 129.355 147.441 1.00 278.35 ?  511  LEU A O   1 
ATOM   3002 C CB  . LEU A 1 511 ? 103.994 129.193 150.313 1.00 278.35 ?  511  LEU A CB  1 
ATOM   3003 C CG  . LEU A 1 511 ? 104.045 127.741 150.785 1.00 278.35 ?  511  LEU A CG  1 
ATOM   3004 C CD1 . LEU A 1 511 ? 104.450 127.681 152.246 1.00 278.35 ?  511  LEU A CD1 1 
ATOM   3005 C CD2 . LEU A 1 511 ? 102.703 127.059 150.578 1.00 278.35 ?  511  LEU A CD2 1 
ATOM   3006 N N   . PHE A 1 512 ? 104.996 128.034 147.218 1.00 288.57 ?  512  PHE A N   1 
ATOM   3007 C CA  . PHE A 1 512 ? 104.434 127.396 146.041 1.00 288.57 ?  512  PHE A CA  1 
ATOM   3008 C C   . PHE A 1 512 ? 103.902 126.026 146.395 1.00 288.57 ?  512  PHE A C   1 
ATOM   3009 O O   . PHE A 1 512 ? 102.694 125.800 146.380 1.00 288.57 ?  512  PHE A O   1 
ATOM   3010 C CB  . PHE A 1 512 ? 105.455 127.274 144.913 1.00 288.57 ?  512  PHE A CB  1 
ATOM   3011 C CG  . PHE A 1 512 ? 104.843 126.897 143.604 1.00 288.57 ?  512  PHE A CG  1 
ATOM   3012 C CD1 . PHE A 1 512 ? 103.898 127.714 143.014 1.00 288.57 ?  512  PHE A CD1 1 
ATOM   3013 C CD2 . PHE A 1 512 ? 105.186 125.714 142.979 1.00 288.57 ?  512  PHE A CD2 1 
ATOM   3014 C CE1 . PHE A 1 512 ? 103.315 127.367 141.814 1.00 288.57 ?  512  PHE A CE1 1 
ATOM   3015 C CE2 . PHE A 1 512 ? 104.606 125.355 141.782 1.00 288.57 ?  512  PHE A CE2 1 
ATOM   3016 C CZ  . PHE A 1 512 ? 103.666 126.183 141.198 1.00 288.57 ?  512  PHE A CZ  1 
ATOM   3017 N N   . ASP A 1 513 ? 104.803 125.105 146.699 1.00 309.02 ?  513  ASP A N   1 
ATOM   3018 C CA  . ASP A 1 513 ? 104.391 123.759 147.047 1.00 309.02 ?  513  ASP A CA  1 
ATOM   3019 C C   . ASP A 1 513 ? 104.066 123.747 148.516 1.00 309.02 ?  513  ASP A C   1 
ATOM   3020 O O   . ASP A 1 513 ? 102.911 123.903 148.907 1.00 309.02 ?  513  ASP A O   1 
ATOM   3021 C CB  . ASP A 1 513 ? 105.525 122.778 146.763 1.00 309.02 ?  513  ASP A CB  1 
ATOM   3022 C CG  . ASP A 1 513 ? 106.417 123.230 145.620 1.00 309.02 ?  513  ASP A CG  1 
ATOM   3023 O OD1 . ASP A 1 513 ? 107.360 124.015 145.859 1.00 309.02 ?  513  ASP A OD1 1 
ATOM   3024 O OD2 . ASP A 1 513 ? 106.174 122.795 144.477 1.00 309.02 -1 513  ASP A OD2 1 
ATOM   3025 N N   . ASP A 1 514 ? 105.082 123.551 149.339 1.00 319.74 ?  514  ASP A N   1 
ATOM   3026 C CA  . ASP A 1 514 ? 104.892 123.580 150.776 1.00 319.74 ?  514  ASP A CA  1 
ATOM   3027 C C   . ASP A 1 514 ? 106.105 124.324 151.254 1.00 319.74 ?  514  ASP A C   1 
ATOM   3028 O O   . ASP A 1 514 ? 106.292 124.536 152.450 1.00 319.74 ?  514  ASP A O   1 
ATOM   3029 C CB  . ASP A 1 514 ? 104.882 122.166 151.344 1.00 319.74 ?  514  ASP A CB  1 
ATOM   3030 C CG  . ASP A 1 514 ? 105.715 121.203 150.521 1.00 319.74 ?  514  ASP A CG  1 
ATOM   3031 O OD1 . ASP A 1 514 ? 106.949 121.159 150.714 1.00 319.74 ?  514  ASP A OD1 1 
ATOM   3032 O OD2 . ASP A 1 514 ? 105.136 120.487 149.679 1.00 319.74 -1 514  ASP A OD2 1 
ATOM   3033 N N   . ILE A 1 515 ? 106.944 124.720 150.306 1.00 292.48 ?  515  ILE A N   1 
ATOM   3034 C CA  . ILE A 1 515 ? 108.161 125.427 150.652 1.00 292.48 ?  515  ILE A CA  1 
ATOM   3035 C C   . ILE A 1 515 ? 108.002 126.909 150.437 1.00 292.48 ?  515  ILE A C   1 
ATOM   3036 O O   . ILE A 1 515 ? 107.464 127.332 149.421 1.00 292.48 ?  515  ILE A O   1 
ATOM   3037 C CB  . ILE A 1 515 ? 109.333 124.942 149.789 1.00 292.48 ?  515  ILE A CB  1 
ATOM   3038 C CG1 . ILE A 1 515 ? 108.906 123.745 148.941 1.00 292.48 ?  515  ILE A CG1 1 
ATOM   3039 C CG2 . ILE A 1 515 ? 110.525 124.590 150.663 1.00 292.48 ?  515  ILE A CG2 1 
ATOM   3040 C CD1 . ILE A 1 515 ? 109.974 122.688 148.780 1.00 292.48 ?  515  ILE A CD1 1 
ATOM   3041 N N   . ILE A 1 516 ? 108.448 127.705 151.399 1.00 282.09 ?  516  ILE A N   1 
ATOM   3042 C CA  . ILE A 1 516 ? 108.413 129.146 151.224 1.00 282.09 ?  516  ILE A CA  1 
ATOM   3043 C C   . ILE A 1 516 ? 109.720 129.537 150.586 1.00 282.09 ?  516  ILE A C   1 
ATOM   3044 O O   . ILE A 1 516 ? 110.782 129.094 151.014 1.00 282.09 ?  516  ILE A O   1 
ATOM   3045 C CB  . ILE A 1 516 ? 108.273 129.896 152.552 1.00 282.09 ?  516  ILE A CB  1 
ATOM   3046 C CG1 . ILE A 1 516 ? 107.902 128.927 153.673 1.00 282.09 ?  516  ILE A CG1 1 
ATOM   3047 C CG2 . ILE A 1 516 ? 107.237 131.002 152.424 1.00 282.09 ?  516  ILE A CG2 1 
ATOM   3048 C CD1 . ILE A 1 516 ? 107.064 129.556 154.763 1.00 282.09 ?  516  ILE A CD1 1 
ATOM   3049 N N   . TYR A 1 517 ? 109.653 130.359 149.553 1.00 286.12 ?  517  TYR A N   1 
ATOM   3050 C CA  . TYR A 1 517 ? 110.857 130.738 148.847 1.00 286.12 ?  517  TYR A CA  1 
ATOM   3051 C C   . TYR A 1 517 ? 111.120 132.207 149.023 1.00 286.12 ?  517  TYR A C   1 
ATOM   3052 O O   . TYR A 1 517 ? 110.485 133.033 148.372 1.00 286.12 ?  517  TYR A O   1 
ATOM   3053 C CB  . TYR A 1 517 ? 110.720 130.439 147.365 1.00 286.12 ?  517  TYR A CB  1 
ATOM   3054 C CG  . TYR A 1 517 ? 110.740 128.975 146.990 1.00 286.12 ?  517  TYR A CG  1 
ATOM   3055 C CD1 . TYR A 1 517 ? 109.604 128.194 147.110 1.00 286.12 ?  517  TYR A CD1 1 
ATOM   3056 C CD2 . TYR A 1 517 ? 111.882 128.386 146.474 1.00 286.12 ?  517  TYR A CD2 1 
ATOM   3057 C CE1 . TYR A 1 517 ? 109.599 126.873 146.737 1.00 286.12 ?  517  TYR A CE1 1 
ATOM   3058 C CE2 . TYR A 1 517 ? 111.889 127.055 146.110 1.00 286.12 ?  517  TYR A CE2 1 
ATOM   3059 C CZ  . TYR A 1 517 ? 110.742 126.308 146.250 1.00 286.12 ?  517  TYR A CZ  1 
ATOM   3060 O OH  . TYR A 1 517 ? 110.723 124.989 145.896 1.00 286.12 ?  517  TYR A OH  1 
ATOM   3061 N N   . LYS A 1 518 ? 112.061 132.543 149.896 1.00 248.57 ?  518  LYS A N   1 
ATOM   3062 C CA  . LYS A 1 518 ? 112.424 133.935 150.092 1.00 248.57 ?  518  LYS A CA  1 
ATOM   3063 C C   . LYS A 1 518 ? 113.002 134.481 148.801 1.00 248.57 ?  518  LYS A C   1 
ATOM   3064 O O   . LYS A 1 518 ? 113.825 133.827 148.163 1.00 248.57 ?  518  LYS A O   1 
ATOM   3065 C CB  . LYS A 1 518 ? 113.428 134.070 151.231 1.00 248.57 ?  518  LYS A CB  1 
ATOM   3066 C CG  . LYS A 1 518 ? 113.497 135.455 151.858 1.00 248.57 ?  518  LYS A CG  1 
ATOM   3067 C CD  . LYS A 1 518 ? 112.129 136.108 151.980 1.00 248.57 ?  518  LYS A CD  1 
ATOM   3068 C CE  . LYS A 1 518 ? 112.238 137.619 151.850 1.00 248.57 ?  518  LYS A CE  1 
ATOM   3069 N NZ  . LYS A 1 518 ? 111.659 138.121 150.576 1.00 248.57 1  518  LYS A NZ  1 
ATOM   3070 N N   . ILE A 1 519 ? 112.577 135.677 148.411 1.00 216.28 ?  519  ILE A N   1 
ATOM   3071 C CA  . ILE A 1 519 ? 113.034 136.258 147.161 1.00 216.28 ?  519  ILE A CA  1 
ATOM   3072 C C   . ILE A 1 519 ? 114.527 136.538 147.153 1.00 216.28 ?  519  ILE A C   1 
ATOM   3073 O O   . ILE A 1 519 ? 115.042 137.119 148.101 1.00 216.28 ?  519  ILE A O   1 
ATOM   3074 C CB  . ILE A 1 519 ? 112.285 137.580 146.915 1.00 216.28 ?  519  ILE A CB  1 
ATOM   3075 C CG1 . ILE A 1 519 ? 110.782 137.375 147.114 1.00 216.28 ?  519  ILE A CG1 1 
ATOM   3076 C CG2 . ILE A 1 519 ? 112.575 138.137 145.536 1.00 216.28 ?  519  ILE A CG2 1 
ATOM   3077 C CD1 . ILE A 1 519 ? 110.068 136.905 145.872 1.00 216.28 ?  519  ILE A CD1 1 
ATOM   3078 N N   . LEU A 1 520 ? 115.231 136.096 146.112 1.00 225.65 ?  520  LEU A N   1 
ATOM   3079 C CA  . LEU A 1 520 ? 116.648 136.415 145.976 1.00 225.65 ?  520  LEU A CA  1 
ATOM   3080 C C   . LEU A 1 520 ? 116.746 137.588 144.965 1.00 225.65 ?  520  LEU A C   1 
ATOM   3081 O O   . LEU A 1 520 ? 116.767 137.324 143.771 1.00 225.65 ?  520  LEU A O   1 
ATOM   3082 C CB  . LEU A 1 520 ? 117.458 135.219 145.488 1.00 225.65 ?  520  LEU A CB  1 
ATOM   3083 C CG  . LEU A 1 520 ? 118.882 135.021 146.019 1.00 225.65 ?  520  LEU A CG  1 
ATOM   3084 C CD1 . LEU A 1 520 ? 119.489 136.299 146.570 1.00 225.65 ?  520  LEU A CD1 1 
ATOM   3085 C CD2 . LEU A 1 520 ? 118.935 133.925 147.069 1.00 225.65 ?  520  LEU A CD2 1 
ATOM   3086 N N   . PRO A 1 521 ? 116.817 138.883 145.425 1.00 240.84 ?  521  PRO A N   1 
ATOM   3087 C CA  . PRO A 1 521 ? 116.847 139.934 144.404 1.00 240.84 ?  521  PRO A CA  1 
ATOM   3088 C C   . PRO A 1 521 ? 118.078 139.884 143.511 1.00 240.84 ?  521  PRO A C   1 
ATOM   3089 O O   . PRO A 1 521 ? 118.020 140.369 142.388 1.00 240.84 ?  521  PRO A O   1 
ATOM   3090 C CB  . PRO A 1 521 ? 116.848 141.211 145.237 1.00 240.84 ?  521  PRO A CB  1 
ATOM   3091 C CG  . PRO A 1 521 ? 116.346 140.816 146.580 1.00 240.84 ?  521  PRO A CG  1 
ATOM   3092 C CD  . PRO A 1 521 ? 116.897 139.447 146.779 1.00 240.84 ?  521  PRO A CD  1 
ATOM   3093 N N   . GLY A 1 522 ? 119.174 139.305 143.991 1.00 248.08 ?  522  GLY A N   1 
ATOM   3094 C CA  . GLY A 1 522 ? 120.376 139.186 143.197 1.00 248.08 ?  522  GLY A CA  1 
ATOM   3095 C C   . GLY A 1 522 ? 120.222 138.156 142.116 1.00 248.08 ?  522  GLY A C   1 
ATOM   3096 O O   . GLY A 1 522 ? 120.868 138.253 141.088 1.00 248.08 ?  522  GLY A O   1 
ATOM   3097 N N   . GLY A 1 523 ? 119.378 137.160 142.343 1.00 250.29 ?  523  GLY A N   1 
ATOM   3098 C CA  . GLY A 1 523 ? 119.116 136.161 141.328 1.00 250.29 ?  523  GLY A CA  1 
ATOM   3099 C C   . GLY A 1 523 ? 118.376 136.823 140.208 1.00 250.29 ?  523  GLY A C   1 
ATOM   3100 O O   . GLY A 1 523 ? 118.690 136.588 139.056 1.00 250.29 ?  523  GLY A O   1 
ATOM   3101 N N   . TYR A 1 524 ? 117.421 137.681 140.541 1.00 229.92 ?  524  TYR A N   1 
ATOM   3102 C CA  . TYR A 1 524 ? 116.670 138.418 139.537 1.00 229.92 ?  524  TYR A CA  1 
ATOM   3103 C C   . TYR A 1 524 ? 117.601 139.291 138.733 1.00 229.92 ?  524  TYR A C   1 
ATOM   3104 O O   . TYR A 1 524 ? 117.395 139.477 137.541 1.00 229.92 ?  524  TYR A O   1 
ATOM   3105 C CB  . TYR A 1 524 ? 115.637 139.304 140.216 1.00 229.92 ?  524  TYR A CB  1 
ATOM   3106 C CG  . TYR A 1 524 ? 114.378 138.618 140.668 1.00 229.92 ?  524  TYR A CG  1 
ATOM   3107 C CD1 . TYR A 1 524 ? 114.380 137.781 141.768 1.00 229.92 ?  524  TYR A CD1 1 
ATOM   3108 C CD2 . TYR A 1 524 ? 113.178 138.837 140.016 1.00 229.92 ?  524  TYR A CD2 1 
ATOM   3109 C CE1 . TYR A 1 524 ? 113.231 137.156 142.189 1.00 229.92 ?  524  TYR A CE1 1 
ATOM   3110 C CE2 . TYR A 1 524 ? 112.021 138.218 140.432 1.00 229.92 ?  524  TYR A CE2 1 
ATOM   3111 C CZ  . TYR A 1 524 ? 112.057 137.380 141.520 1.00 229.92 ?  524  TYR A CZ  1 
ATOM   3112 O OH  . TYR A 1 524 ? 110.918 136.759 141.945 1.00 229.92 ?  524  TYR A OH  1 
ATOM   3113 N N   . ALA A 1 525 ? 118.624 139.836 139.376 1.00 256.65 ?  525  ALA A N   1 
ATOM   3114 C CA  . ALA A 1 525 ? 119.598 140.661 138.683 1.00 256.65 ?  525  ALA A CA  1 
ATOM   3115 C C   . ALA A 1 525 ? 120.379 139.900 137.630 1.00 256.65 ?  525  ALA A C   1 
ATOM   3116 O O   . ALA A 1 525 ? 120.604 140.419 136.552 1.00 256.65 ?  525  ALA A O   1 
ATOM   3117 C CB  . ALA A 1 525 ? 120.534 141.297 139.680 1.00 256.65 ?  525  ALA A CB  1 
ATOM   3118 N N   . VAL A 1 526 ? 120.792 138.673 137.929 1.00 270.30 ?  526  VAL A N   1 
ATOM   3119 C CA  . VAL A 1 526 ? 121.488 137.852 136.941 1.00 270.30 ?  526  VAL A CA  1 
ATOM   3120 C C   . VAL A 1 526 ? 120.592 137.607 135.735 1.00 270.30 ?  526  VAL A C   1 
ATOM   3121 O O   . VAL A 1 526 ? 121.026 137.728 134.593 1.00 270.30 ?  526  VAL A O   1 
ATOM   3122 C CB  . VAL A 1 526 ? 121.978 136.517 137.544 1.00 270.30 ?  526  VAL A CB  1 
ATOM   3123 C CG1 . VAL A 1 526 ? 122.939 135.812 136.607 1.00 270.30 ?  526  VAL A CG1 1 
ATOM   3124 C CG2 . VAL A 1 526 ? 122.659 136.741 138.878 1.00 270.30 ?  526  VAL A CG2 1 
ATOM   3125 N N   . ILE A 1 527 ? 119.330 137.288 135.980 1.00 254.86 ?  527  ILE A N   1 
ATOM   3126 C CA  . ILE A 1 527 ? 118.389 137.087 134.886 1.00 254.86 ?  527  ILE A CA  1 
ATOM   3127 C C   . ILE A 1 527 ? 118.264 138.343 134.053 1.00 254.86 ?  527  ILE A C   1 
ATOM   3128 O O   . ILE A 1 527 ? 118.359 138.287 132.835 1.00 254.86 ?  527  ILE A O   1 
ATOM   3129 C CB  . ILE A 1 527 ? 117.004 136.702 135.413 1.00 254.86 ?  527  ILE A CB  1 
ATOM   3130 C CG1 . ILE A 1 527 ? 117.138 135.690 136.531 1.00 254.86 ?  527  ILE A CG1 1 
ATOM   3131 C CG2 . ILE A 1 527 ? 116.149 136.106 134.322 1.00 254.86 ?  527  ILE A CG2 1 
ATOM   3132 C CD1 . ILE A 1 527 ? 116.694 134.312 136.148 1.00 254.86 ?  527  ILE A CD1 1 
ATOM   3133 N N   . GLY A 1 528 ? 118.063 139.479 134.703 1.00 250.40 ?  528  GLY A N   1 
ATOM   3134 C CA  . GLY A 1 528 ? 117.941 140.731 133.994 1.00 250.40 ?  528  GLY A CA  1 
ATOM   3135 C C   . GLY A 1 528 ? 119.149 141.090 133.176 1.00 250.40 ?  528  GLY A C   1 
ATOM   3136 O O   . GLY A 1 528 ? 119.005 141.597 132.076 1.00 250.40 ?  528  GLY A O   1 
ATOM   3137 N N   . ALA A 1 529 ? 120.338 140.852 133.709 1.00 232.85 ?  529  ALA A N   1 
ATOM   3138 C CA  . ALA A 1 529 ? 121.563 141.130 132.985 1.00 232.85 ?  529  ALA A CA  1 
ATOM   3139 C C   . ALA A 1 529 ? 121.553 140.376 131.690 1.00 232.85 ?  529  ALA A C   1 
ATOM   3140 O O   . ALA A 1 529 ? 121.683 140.974 130.634 1.00 232.85 ?  529  ALA A O   1 
ATOM   3141 C CB  . ALA A 1 529 ? 122.758 140.735 133.819 1.00 232.85 ?  529  ALA A CB  1 
ATOM   3142 N N   . ALA A 1 530 ? 121.359 139.065 131.760 1.00 253.14 ?  530  ALA A N   1 
ATOM   3143 C CA  . ALA A 1 530 ? 121.310 138.234 130.569 1.00 253.14 ?  530  ALA A CA  1 
ATOM   3144 C C   . ALA A 1 530 ? 120.210 138.630 129.611 1.00 253.14 ?  530  ALA A C   1 
ATOM   3145 O O   . ALA A 1 530 ? 120.389 138.564 128.406 1.00 253.14 ?  530  ALA A O   1 
ATOM   3146 C CB  . ALA A 1 530 ? 121.129 136.790 130.971 1.00 253.14 ?  530  ALA A CB  1 
ATOM   3147 N N   . ALA A 1 531 ? 119.063 139.026 130.137 1.00 261.07 ?  531  ALA A N   1 
ATOM   3148 C CA  . ALA A 1 531 ? 117.944 139.376 129.289 1.00 261.07 ?  531  ALA A CA  1 
ATOM   3149 C C   . ALA A 1 531 ? 118.162 140.687 128.541 1.00 261.07 ?  531  ALA A C   1 
ATOM   3150 O O   . ALA A 1 531 ? 117.882 140.759 127.358 1.00 261.07 ?  531  ALA A O   1 
ATOM   3151 C CB  . ALA A 1 531 ? 116.655 139.398 130.089 1.00 261.07 ?  531  ALA A CB  1 
ATOM   3152 N N   . LEU A 1 532 ? 118.669 141.719 129.204 1.00 256.25 ?  532  LEU A N   1 
ATOM   3153 C CA  . LEU A 1 532 ? 118.828 142.996 128.530 1.00 256.25 ?  532  LEU A CA  1 
ATOM   3154 C C   . LEU A 1 532 ? 119.957 142.910 127.538 1.00 256.25 ?  532  LEU A C   1 
ATOM   3155 O O   . LEU A 1 532 ? 119.863 143.438 126.437 1.00 256.25 ?  532  LEU A O   1 
ATOM   3156 C CB  . LEU A 1 532 ? 119.054 144.158 129.503 1.00 256.25 ?  532  LEU A CB  1 
ATOM   3157 C CG  . LEU A 1 532 ? 118.089 145.343 129.350 1.00 256.25 ?  532  LEU A CG  1 
ATOM   3158 C CD1 . LEU A 1 532 ? 117.835 146.088 130.648 1.00 256.25 ?  532  LEU A CD1 1 
ATOM   3159 C CD2 . LEU A 1 532 ? 118.497 146.321 128.267 1.00 256.25 ?  532  LEU A CD2 1 
ATOM   3160 N N   . THR A 1 533 ? 121.027 142.225 127.916 1.00 240.29 ?  533  THR A N   1 
ATOM   3161 C CA  . THR A 1 533 ? 122.156 142.088 127.019 1.00 240.29 ?  533  THR A CA  1 
ATOM   3162 C C   . THR A 1 533 ? 121.871 141.080 125.909 1.00 240.29 ?  533  THR A C   1 
ATOM   3163 O O   . THR A 1 533 ? 122.545 141.084 124.892 1.00 240.29 ?  533  THR A O   1 
ATOM   3164 C CB  . THR A 1 533 ? 123.487 141.861 127.781 1.00 240.29 ?  533  THR A CB  1 
ATOM   3165 O OG1 . THR A 1 533 ? 124.586 142.281 126.964 1.00 240.29 ?  533  THR A OG1 1 
ATOM   3166 C CG2 . THR A 1 533 ? 123.668 140.430 128.171 1.00 240.29 ?  533  THR A CG2 1 
ATOM   3167 N N   . GLY A 1 534 ? 120.847 140.250 126.075 1.00 242.01 ?  534  GLY A N   1 
ATOM   3168 C CA  . GLY A 1 534 ? 120.460 139.318 125.032 1.00 242.01 ?  534  GLY A CA  1 
ATOM   3169 C C   . GLY A 1 534 ? 119.465 139.965 124.107 1.00 242.01 ?  534  GLY A C   1 
ATOM   3170 O O   . GLY A 1 534 ? 119.290 139.525 122.987 1.00 242.01 ?  534  GLY A O   1 
ATOM   3171 N N   . ALA A 1 535 ? 118.806 141.014 124.571 1.00 218.20 ?  535  ALA A N   1 
ATOM   3172 C CA  . ALA A 1 535 ? 117.879 141.750 123.736 1.00 218.20 ?  535  ALA A CA  1 
ATOM   3173 C C   . ALA A 1 535 ? 118.620 142.802 122.936 1.00 218.20 ?  535  ALA A C   1 
ATOM   3174 O O   . ALA A 1 535 ? 118.136 143.273 121.918 1.00 218.20 ?  535  ALA A O   1 
ATOM   3175 C CB  . ALA A 1 535 ? 116.857 142.422 124.610 1.00 218.20 ?  535  ALA A CB  1 
ATOM   3176 N N   . VAL A 1 536 ? 119.794 143.194 123.405 1.00 228.69 ?  536  VAL A N   1 
ATOM   3177 C CA  . VAL A 1 536 ? 120.577 144.191 122.702 1.00 228.69 ?  536  VAL A CA  1 
ATOM   3178 C C   . VAL A 1 536 ? 121.388 143.491 121.627 1.00 228.69 ?  536  VAL A C   1 
ATOM   3179 O O   . VAL A 1 536 ? 121.498 143.981 120.515 1.00 228.69 ?  536  VAL A O   1 
ATOM   3180 C CB  . VAL A 1 536 ? 121.437 145.014 123.696 1.00 228.69 ?  536  VAL A CB  1 
ATOM   3181 C CG1 . VAL A 1 536 ? 122.864 145.228 123.219 1.00 228.69 ?  536  VAL A CG1 1 
ATOM   3182 C CG2 . VAL A 1 536 ? 120.772 146.341 124.001 1.00 228.69 ?  536  VAL A CG2 1 
ATOM   3183 N N   . SER A 1 537 ? 121.896 142.305 121.931 1.00 244.47 ?  537  SER A N   1 
ATOM   3184 C CA  . SER A 1 537 ? 122.731 141.590 120.988 1.00 244.47 ?  537  SER A CA  1 
ATOM   3185 C C   . SER A 1 537 ? 121.948 140.601 120.169 1.00 244.47 ?  537  SER A C   1 
ATOM   3186 O O   . SER A 1 537 ? 122.518 139.991 119.266 1.00 244.47 ?  537  SER A O   1 
ATOM   3187 C CB  . SER A 1 537 ? 123.802 140.831 121.750 1.00 244.47 ?  537  SER A CB  1 
ATOM   3188 O OG  . SER A 1 537 ? 123.223 139.823 122.546 1.00 244.47 ?  537  SER A OG  1 
ATOM   3189 N N   . HIS A 1 538 ? 120.664 140.429 120.474 1.00 246.50 ?  538  HIS A N   1 
ATOM   3190 C CA  . HIS A 1 538 ? 119.813 139.454 119.782 1.00 246.50 ?  538  HIS A CA  1 
ATOM   3191 C C   . HIS A 1 538 ? 120.362 138.046 119.881 1.00 246.50 ?  538  HIS A C   1 
ATOM   3192 O O   . HIS A 1 538 ? 120.391 137.320 118.894 1.00 246.50 ?  538  HIS A O   1 
ATOM   3193 C CB  . HIS A 1 538 ? 119.524 139.853 118.337 1.00 246.50 ?  538  HIS A CB  1 
ATOM   3194 C CG  . HIS A 1 538 ? 118.501 140.931 118.206 1.00 246.50 ?  538  HIS A CG  1 
ATOM   3195 N ND1 . HIS A 1 538 ? 118.024 141.354 116.986 1.00 246.50 ?  538  HIS A ND1 1 
ATOM   3196 C CD2 . HIS A 1 538 ? 117.862 141.673 119.140 1.00 246.50 ?  538  HIS A CD2 1 
ATOM   3197 C CE1 . HIS A 1 538 ? 117.133 142.309 117.175 1.00 246.50 ?  538  HIS A CE1 1 
ATOM   3198 N NE2 . HIS A 1 538 ? 117.021 142.526 118.472 1.00 246.50 ?  538  HIS A NE2 1 
ATOM   3199 N N   . THR A 1 539 ? 120.795 137.654 121.076 1.00 247.03 ?  539  THR A N   1 
ATOM   3200 C CA  . THR A 1 539 ? 121.328 136.317 121.290 1.00 247.03 ?  539  THR A CA  1 
ATOM   3201 C C   . THR A 1 539 ? 120.758 135.705 122.543 1.00 247.03 ?  539  THR A C   1 
ATOM   3202 O O   . THR A 1 539 ? 120.332 136.408 123.443 1.00 247.03 ?  539  THR A O   1 
ATOM   3203 C CB  . THR A 1 539 ? 122.846 136.323 121.506 1.00 247.03 ?  539  THR A CB  1 
ATOM   3204 O OG1 . THR A 1 539 ? 123.157 137.099 122.663 1.00 247.03 ?  539  THR A OG1 1 
ATOM   3205 C CG2 . THR A 1 539 ? 123.565 136.872 120.319 1.00 247.03 ?  539  THR A CG2 1 
ATOM   3206 N N   . VAL A 1 540 ? 120.770 134.384 122.618 1.00 231.76 ?  540  VAL A N   1 
ATOM   3207 C CA  . VAL A 1 540 ? 120.289 133.705 123.807 1.00 231.76 ?  540  VAL A CA  1 
ATOM   3208 C C   . VAL A 1 540 ? 121.459 133.094 124.552 1.00 231.76 ?  540  VAL A C   1 
ATOM   3209 O O   . VAL A 1 540 ? 121.275 132.433 125.567 1.00 231.76 ?  540  VAL A O   1 
ATOM   3210 C CB  . VAL A 1 540 ? 119.268 132.613 123.452 1.00 231.76 ?  540  VAL A CB  1 
ATOM   3211 C CG1 . VAL A 1 540 ? 117.867 133.202 123.372 1.00 231.76 ?  540  VAL A CG1 1 
ATOM   3212 C CG2 . VAL A 1 540 ? 119.643 131.942 122.142 1.00 231.76 ?  540  VAL A CG2 1 
ATOM   3213 N N   . SER A 1 541 ? 122.671 133.332 124.065 1.00 248.46 ?  541  SER A N   1 
ATOM   3214 C CA  . SER A 1 541 ? 123.862 132.759 124.679 1.00 248.46 ?  541  SER A CA  1 
ATOM   3215 C C   . SER A 1 541 ? 124.331 133.575 125.846 1.00 248.46 ?  541  SER A C   1 
ATOM   3216 O O   . SER A 1 541 ? 125.263 133.190 126.535 1.00 248.46 ?  541  SER A O   1 
ATOM   3217 C CB  . SER A 1 541 ? 124.974 132.709 123.662 1.00 248.46 ?  541  SER A CB  1 
ATOM   3218 O OG  . SER A 1 541 ? 124.855 133.790 122.763 1.00 248.46 ?  541  SER A OG  1 
ATOM   3219 N N   . THR A 1 542 ? 123.689 134.707 126.078 1.00 250.86 ?  542  THR A N   1 
ATOM   3220 C CA  . THR A 1 542 ? 124.037 135.554 127.197 1.00 250.86 ?  542  THR A CA  1 
ATOM   3221 C C   . THR A 1 542 ? 123.606 134.877 128.468 1.00 250.86 ?  542  THR A C   1 
ATOM   3222 O O   . THR A 1 542 ? 124.149 135.154 129.522 1.00 250.86 ?  542  THR A O   1 
ATOM   3223 C CB  . THR A 1 542 ? 123.332 136.892 127.067 1.00 250.86 ?  542  THR A CB  1 
ATOM   3224 O OG1 . THR A 1 542 ? 121.924 136.671 126.938 1.00 250.86 ?  542  THR A OG1 1 
ATOM   3225 C CG2 . THR A 1 542 ? 123.824 137.594 125.835 1.00 250.86 ?  542  THR A CG2 1 
ATOM   3226 N N   . ALA A 1 543 ? 122.622 133.991 128.377 1.00 235.53 ?  543  ALA A N   1 
ATOM   3227 C CA  . ALA A 1 543 ? 122.197 133.228 129.531 1.00 235.53 ?  543  ALA A CA  1 
ATOM   3228 C C   . ALA A 1 543 ? 123.344 132.348 129.958 1.00 235.53 ?  543  ALA A C   1 
ATOM   3229 O O   . ALA A 1 543 ? 123.662 132.289 131.133 1.00 235.53 ?  543  ALA A O   1 
ATOM   3230 C CB  . ALA A 1 543 ? 120.988 132.389 129.178 1.00 235.53 ?  543  ALA A CB  1 
ATOM   3231 N N   . VAL A 1 544 ? 123.980 131.675 129.004 1.00 243.13 ?  544  VAL A N   1 
ATOM   3232 C CA  . VAL A 1 544 ? 125.127 130.822 129.303 1.00 243.13 ?  544  VAL A CA  1 
ATOM   3233 C C   . VAL A 1 544 ? 126.309 131.632 129.803 1.00 243.13 ?  544  VAL A C   1 
ATOM   3234 O O   . VAL A 1 544 ? 126.999 131.217 130.728 1.00 243.13 ?  544  VAL A O   1 
ATOM   3235 C CB  . VAL A 1 544 ? 125.552 130.008 128.071 1.00 243.13 ?  544  VAL A CB  1 
ATOM   3236 C CG1 . VAL A 1 544 ? 126.194 128.697 128.493 1.00 243.13 ?  544  VAL A CG1 1 
ATOM   3237 C CG2 . VAL A 1 544 ? 124.351 129.743 127.177 1.00 243.13 ?  544  VAL A CG2 1 
ATOM   3238 N N   . ILE A 1 545 ? 126.547 132.791 129.202 1.00 258.02 ?  545  ILE A N   1 
ATOM   3239 C CA  . ILE A 1 545 ? 127.616 133.657 129.669 1.00 258.02 ?  545  ILE A CA  1 
ATOM   3240 C C   . ILE A 1 545 ? 127.358 133.993 131.121 1.00 258.02 ?  545  ILE A C   1 
ATOM   3241 O O   . ILE A 1 545 ? 128.243 133.856 131.954 1.00 258.02 ?  545  ILE A O   1 
ATOM   3242 C CB  . ILE A 1 545 ? 127.732 134.932 128.815 1.00 258.02 ?  545  ILE A CB  1 
ATOM   3243 C CG1 . ILE A 1 545 ? 128.209 134.587 127.410 1.00 258.02 ?  545  ILE A CG1 1 
ATOM   3244 C CG2 . ILE A 1 545 ? 128.696 135.930 129.438 1.00 258.02 ?  545  ILE A CG2 1 
ATOM   3245 C CD1 . ILE A 1 545 ? 128.156 135.744 126.445 1.00 258.02 ?  545  ILE A CD1 1 
ATOM   3246 N N   . CYS A 1 546 ? 126.135 134.392 131.436 1.00 261.36 ?  546  CYS A N   1 
ATOM   3247 C CA  . CYS A 1 546 ? 125.777 134.716 132.807 1.00 261.36 ?  546  CYS A CA  1 
ATOM   3248 C C   . CYS A 1 546 ? 126.009 133.544 133.728 1.00 261.36 ?  546  CYS A C   1 
ATOM   3249 O O   . CYS A 1 546 ? 126.632 133.703 134.750 1.00 261.36 ?  546  CYS A O   1 
ATOM   3250 C CB  . CYS A 1 546 ? 124.321 135.148 132.893 1.00 261.36 ?  546  CYS A CB  1 
ATOM   3251 S SG  . CYS A 1 546 ? 124.089 136.881 133.297 1.00 261.36 ?  546  CYS A SG  1 
ATOM   3252 N N   . PHE A 1 547 ? 125.513 132.368 133.367 1.00 243.82 ?  547  PHE A N   1 
ATOM   3253 C CA  . PHE A 1 547 ? 125.683 131.180 134.193 1.00 243.82 ?  547  PHE A CA  1 
ATOM   3254 C C   . PHE A 1 547 ? 127.126 130.969 134.575 1.00 243.82 ?  547  PHE A C   1 
ATOM   3255 O O   . PHE A 1 547 ? 127.435 130.770 135.739 1.00 243.82 ?  547  PHE A O   1 
ATOM   3256 C CB  . PHE A 1 547 ? 125.218 129.937 133.451 1.00 243.82 ?  547  PHE A CB  1 
ATOM   3257 C CG  . PHE A 1 547 ? 123.736 129.831 133.316 1.00 243.82 ?  547  PHE A CG  1 
ATOM   3258 C CD1 . PHE A 1 547 ? 122.899 130.283 134.317 1.00 243.82 ?  547  PHE A CD1 1 
ATOM   3259 C CD2 . PHE A 1 547 ? 123.180 129.263 132.186 1.00 243.82 ?  547  PHE A CD2 1 
ATOM   3260 C CE1 . PHE A 1 547 ? 121.533 130.174 134.190 1.00 243.82 ?  547  PHE A CE1 1 
ATOM   3261 C CE2 . PHE A 1 547 ? 121.816 129.164 132.046 1.00 243.82 ?  547  PHE A CE2 1 
ATOM   3262 C CZ  . PHE A 1 547 ? 120.993 129.625 133.048 1.00 243.82 ?  547  PHE A CZ  1 
ATOM   3263 N N   . GLU A 1 548 ? 128.015 131.001 133.592 1.00 251.54 ?  548  GLU A N   1 
ATOM   3264 C CA  . GLU A 1 548 ? 129.422 130.769 133.855 1.00 251.54 ?  548  GLU A CA  1 
ATOM   3265 C C   . GLU A 1 548 ? 130.082 131.897 134.625 1.00 251.54 ?  548  GLU A C   1 
ATOM   3266 O O   . GLU A 1 548 ? 130.910 131.638 135.487 1.00 251.54 ?  548  GLU A O   1 
ATOM   3267 C CB  . GLU A 1 548 ? 130.154 130.528 132.545 1.00 251.54 ?  548  GLU A CB  1 
ATOM   3268 C CG  . GLU A 1 548 ? 130.165 129.077 132.108 1.00 251.54 ?  548  GLU A CG  1 
ATOM   3269 C CD  . GLU A 1 548 ? 130.330 128.927 130.613 1.00 251.54 ?  548  GLU A CD  1 
ATOM   3270 O OE1 . GLU A 1 548 ? 129.349 129.164 129.882 1.00 251.54 ?  548  GLU A OE1 1 
ATOM   3271 O OE2 . GLU A 1 548 ? 131.444 128.584 130.170 1.00 251.54 -1 548  GLU A OE2 1 
ATOM   3272 N N   . LEU A 1 549 ? 129.722 133.139 134.330 1.00 243.78 ?  549  LEU A N   1 
ATOM   3273 C CA  . LEU A 1 549 ? 130.271 134.289 135.043 1.00 243.78 ?  549  LEU A CA  1 
ATOM   3274 C C   . LEU A 1 549 ? 129.807 134.302 136.471 1.00 243.78 ?  549  LEU A C   1 
ATOM   3275 O O   . LEU A 1 549 ? 130.509 134.790 137.349 1.00 243.78 ?  549  LEU A O   1 
ATOM   3276 C CB  . LEU A 1 549 ? 129.778 135.575 134.395 1.00 243.78 ?  549  LEU A CB  1 
ATOM   3277 C CG  . LEU A 1 549 ? 130.721 136.339 133.479 1.00 243.78 ?  549  LEU A CG  1 
ATOM   3278 C CD1 . LEU A 1 549 ? 130.026 137.588 132.962 1.00 243.78 ?  549  LEU A CD1 1 
ATOM   3279 C CD2 . LEU A 1 549 ? 131.970 136.699 134.257 1.00 243.78 ?  549  LEU A CD2 1 
ATOM   3280 N N   . THR A 1 550 ? 128.621 133.771 136.714 1.00 250.34 ?  550  THR A N   1 
ATOM   3281 C CA  . THR A 1 550 ? 128.040 133.801 138.040 1.00 250.34 ?  550  THR A CA  1 
ATOM   3282 C C   . THR A 1 550 ? 128.453 132.553 138.795 1.00 250.34 ?  550  THR A C   1 
ATOM   3283 O O   . THR A 1 550 ? 128.447 132.524 140.024 1.00 250.34 ?  550  THR A O   1 
ATOM   3284 C CB  . THR A 1 550 ? 126.510 134.044 137.896 1.00 250.34 ?  550  THR A CB  1 
ATOM   3285 O OG1 . THR A 1 550 ? 126.169 135.331 138.417 1.00 250.34 ?  550  THR A OG1 1 
ATOM   3286 C CG2 . THR A 1 550 ? 125.645 132.965 138.513 1.00 250.34 ?  550  THR A CG2 1 
ATOM   3287 N N   . GLY A 1 551 ? 128.859 131.525 138.062 1.00 251.09 ?  551  GLY A N   1 
ATOM   3288 C CA  . GLY A 1 551 ? 129.307 130.296 138.690 1.00 251.09 ?  551  GLY A CA  1 
ATOM   3289 C C   . GLY A 1 551 ? 128.169 129.414 139.135 1.00 251.09 ?  551  GLY A C   1 
ATOM   3290 O O   . GLY A 1 551 ? 128.400 128.374 139.747 1.00 251.09 ?  551  GLY A O   1 
ATOM   3291 N N   . GLN A 1 552 ? 126.939 129.812 138.833 1.00 247.59 ?  552  GLN A N   1 
ATOM   3292 C CA  . GLN A 1 552 ? 125.780 129.051 139.279 1.00 247.59 ?  552  GLN A CA  1 
ATOM   3293 C C   . GLN A 1 552 ? 124.751 128.908 138.173 1.00 247.59 ?  552  GLN A C   1 
ATOM   3294 O O   . GLN A 1 552 ? 124.625 129.788 137.328 1.00 247.59 ?  552  GLN A O   1 
ATOM   3295 C CB  . GLN A 1 552 ? 125.156 129.708 140.508 1.00 247.59 ?  552  GLN A CB  1 
ATOM   3296 C CG  . GLN A 1 552 ? 125.674 129.171 141.831 1.00 247.59 ?  552  GLN A CG  1 
ATOM   3297 C CD  . GLN A 1 552 ? 125.278 130.038 143.006 1.00 247.59 ?  552  GLN A CD  1 
ATOM   3298 O OE1 . GLN A 1 552 ? 124.632 131.069 142.841 1.00 247.59 ?  552  GLN A OE1 1 
ATOM   3299 N NE2 . GLN A 1 552 ? 125.665 129.621 144.204 1.00 247.59 ?  552  GLN A NE2 1 
ATOM   3300 N N   . ILE A 1 553 ? 124.016 127.801 138.172 1.00 216.24 ?  553  ILE A N   1 
ATOM   3301 C CA  . ILE A 1 553 ? 123.031 127.551 137.123 1.00 216.24 ?  553  ILE A CA  1 
ATOM   3302 C C   . ILE A 1 553 ? 121.681 127.206 137.721 1.00 216.24 ?  553  ILE A C   1 
ATOM   3303 O O   . ILE A 1 553 ? 120.908 126.471 137.118 1.00 216.24 ?  553  ILE A O   1 
ATOM   3304 C CB  . ILE A 1 553 ? 123.453 126.368 136.234 1.00 216.24 ?  553  ILE A CB  1 
ATOM   3305 C CG1 . ILE A 1 553 ? 124.037 125.242 137.087 1.00 216.24 ?  553  ILE A CG1 1 
ATOM   3306 C CG2 . ILE A 1 553 ? 124.467 126.801 135.191 1.00 216.24 ?  553  ILE A CG2 1 
ATOM   3307 C CD1 . ILE A 1 553 ? 123.653 123.859 136.611 1.00 216.24 ?  553  ILE A CD1 1 
ATOM   3308 N N   . ALA A 1 554 ? 121.389 127.726 138.905 1.00 188.20 ?  554  ALA A N   1 
ATOM   3309 C CA  . ALA A 1 554 ? 120.139 127.388 139.580 1.00 188.20 ?  554  ALA A CA  1 
ATOM   3310 C C   . ALA A 1 554 ? 118.927 127.965 138.876 1.00 188.20 ?  554  ALA A C   1 
ATOM   3311 O O   . ALA A 1 554 ? 117.897 127.305 138.760 1.00 188.20 ?  554  ALA A O   1 
ATOM   3312 C CB  . ALA A 1 554 ? 120.182 127.862 141.023 1.00 188.20 ?  554  ALA A CB  1 
ATOM   3313 N N   . HIS A 1 555 ? 119.041 129.201 138.414 1.00 232.88 ?  555  HIS A N   1 
ATOM   3314 C CA  . HIS A 1 555 ? 117.930 129.848 137.740 1.00 232.88 ?  555  HIS A CA  1 
ATOM   3315 C C   . HIS A 1 555 ? 117.976 129.550 136.258 1.00 232.88 ?  555  HIS A C   1 
ATOM   3316 O O   . HIS A 1 555 ? 117.849 130.460 135.449 1.00 232.88 ?  555  HIS A O   1 
ATOM   3317 C CB  . HIS A 1 555 ? 118.016 131.358 137.941 1.00 232.88 ?  555  HIS A CB  1 
ATOM   3318 C CG  . HIS A 1 555 ? 117.517 131.824 139.272 1.00 232.88 ?  555  HIS A CG  1 
ATOM   3319 N ND1 . HIS A 1 555 ? 116.213 131.651 139.681 1.00 232.88 ?  555  HIS A ND1 1 
ATOM   3320 C CD2 . HIS A 1 555 ? 118.147 132.463 140.286 1.00 232.88 ?  555  HIS A CD2 1 
ATOM   3321 C CE1 . HIS A 1 555 ? 116.061 132.160 140.890 1.00 232.88 ?  555  HIS A CE1 1 
ATOM   3322 N NE2 . HIS A 1 555 ? 117.220 132.660 141.279 1.00 232.88 ?  555  HIS A NE2 1 
ATOM   3323 N N   . ILE A 1 556 ? 118.157 128.286 135.890 1.00 212.91 ?  556  ILE A N   1 
ATOM   3324 C CA  . ILE A 1 556 ? 118.295 127.955 134.475 1.00 212.91 ?  556  ILE A CA  1 
ATOM   3325 C C   . ILE A 1 556 ? 117.013 128.183 133.686 1.00 212.91 ?  556  ILE A C   1 
ATOM   3326 O O   . ILE A 1 556 ? 117.018 128.925 132.710 1.00 212.91 ?  556  ILE A O   1 
ATOM   3327 C CB  . ILE A 1 556 ? 118.896 126.538 134.269 1.00 212.91 ?  556  ILE A CB  1 
ATOM   3328 C CG1 . ILE A 1 556 ? 118.805 126.096 132.808 1.00 212.91 ?  556  ILE A CG1 1 
ATOM   3329 C CG2 . ILE A 1 556 ? 118.262 125.522 135.214 1.00 212.91 ?  556  ILE A CG2 1 
ATOM   3330 C CD1 . ILE A 1 556 ? 120.134 125.675 132.224 1.00 212.91 ?  556  ILE A CD1 1 
ATOM   3331 N N   . LEU A 1 557 ? 115.913 127.580 134.114 1.00 222.33 ?  557  LEU A N   1 
ATOM   3332 C CA  . LEU A 1 557 ? 114.638 127.805 133.451 1.00 222.33 ?  557  LEU A CA  1 
ATOM   3333 C C   . LEU A 1 557 ? 114.195 129.265 133.505 1.00 222.33 ?  557  LEU A C   1 
ATOM   3334 O O   . LEU A 1 557 ? 113.869 129.827 132.468 1.00 222.33 ?  557  LEU A O   1 
ATOM   3335 C CB  . LEU A 1 557 ? 113.556 126.843 133.967 1.00 222.33 ?  557  LEU A CB  1 
ATOM   3336 C CG  . LEU A 1 557 ? 112.494 126.334 132.991 1.00 222.33 ?  557  LEU A CG  1 
ATOM   3337 C CD1 . LEU A 1 557 ? 111.174 127.060 133.199 1.00 222.33 ?  557  LEU A CD1 1 
ATOM   3338 C CD2 . LEU A 1 557 ? 112.957 126.429 131.544 1.00 222.33 ?  557  LEU A CD2 1 
ATOM   3339 N N   . PRO A 1 558 ? 114.178 129.897 134.700 1.00 213.78 ?  558  PRO A N   1 
ATOM   3340 C CA  . PRO A 1 558 ? 113.830 131.320 134.668 1.00 213.78 ?  558  PRO A CA  1 
ATOM   3341 C C   . PRO A 1 558 ? 114.646 132.138 133.663 1.00 213.78 ?  558  PRO A C   1 
ATOM   3342 O O   . PRO A 1 558 ? 114.060 132.949 132.952 1.00 213.78 ?  558  PRO A O   1 
ATOM   3343 C CB  . PRO A 1 558 ? 114.154 131.768 136.083 1.00 213.78 ?  558  PRO A CB  1 
ATOM   3344 C CG  . PRO A 1 558 ? 113.839 130.596 136.909 1.00 213.78 ?  558  PRO A CG  1 
ATOM   3345 C CD  . PRO A 1 558 ? 114.286 129.423 136.095 1.00 213.78 ?  558  PRO A CD  1 
ATOM   3346 N N   . MET A 1 559 ? 115.958 131.927 133.595 1.00 225.71 ?  559  MET A N   1 
ATOM   3347 C CA  . MET A 1 559 ? 116.791 132.683 132.676 1.00 225.71 ?  559  MET A CA  1 
ATOM   3348 C C   . MET A 1 559 ? 116.449 132.390 131.238 1.00 225.71 ?  559  MET A C   1 
ATOM   3349 O O   . MET A 1 559 ? 116.258 133.302 130.461 1.00 225.71 ?  559  MET A O   1 
ATOM   3350 C CB  . MET A 1 559 ? 118.277 132.442 132.911 1.00 225.71 ?  559  MET A CB  1 
ATOM   3351 C CG  . MET A 1 559 ? 119.144 133.626 132.517 1.00 225.71 ?  559  MET A CG  1 
ATOM   3352 S SD  . MET A 1 559 ? 120.751 133.659 133.323 1.00 225.71 ?  559  MET A SD  1 
ATOM   3353 C CE  . MET A 1 559 ? 120.274 133.500 135.040 1.00 225.71 ?  559  MET A CE  1 
ATOM   3354 N N   . MET A 1 560 ? 116.362 131.120 130.882 1.00 228.96 ?  560  MET A N   1 
ATOM   3355 C CA  . MET A 1 560 ? 116.029 130.743 129.524 1.00 228.96 ?  560  MET A CA  1 
ATOM   3356 C C   . MET A 1 560 ? 114.761 131.426 129.078 1.00 228.96 ?  560  MET A C   1 
ATOM   3357 O O   . MET A 1 560 ? 114.753 132.083 128.051 1.00 228.96 ?  560  MET A O   1 
ATOM   3358 C CB  . MET A 1 560 ? 115.872 129.235 129.419 1.00 228.96 ?  560  MET A CB  1 
ATOM   3359 C CG  . MET A 1 560 ? 116.804 128.592 128.413 1.00 228.96 ?  560  MET A CG  1 
ATOM   3360 S SD  . MET A 1 560 ? 118.078 127.607 129.213 1.00 228.96 ?  560  MET A SD  1 
ATOM   3361 C CE  . MET A 1 560 ? 119.493 128.692 129.061 1.00 228.96 ?  560  MET A CE  1 
ATOM   3362 N N   . VAL A 1 561 ? 113.695 131.290 129.854 1.00 228.93 ?  561  VAL A N   1 
ATOM   3363 C CA  . VAL A 1 561 ? 112.435 131.941 129.531 1.00 228.93 ?  561  VAL A CA  1 
ATOM   3364 C C   . VAL A 1 561 ? 112.646 133.426 129.298 1.00 228.93 ?  561  VAL A C   1 
ATOM   3365 O O   . VAL A 1 561 ? 112.293 133.937 128.248 1.00 228.93 ?  561  VAL A O   1 
ATOM   3366 C CB  . VAL A 1 561 ? 111.396 131.706 130.648 1.00 228.93 ?  561  VAL A CB  1 
ATOM   3367 C CG1 . VAL A 1 561 ? 110.166 132.582 130.468 1.00 228.93 ?  561  VAL A CG1 1 
ATOM   3368 C CG2 . VAL A 1 561 ? 110.993 130.242 130.684 1.00 228.93 ?  561  VAL A CG2 1 
ATOM   3369 N N   . ALA A 1 562 ? 113.256 134.112 130.254 1.00 228.46 ?  562  ALA A N   1 
ATOM   3370 C CA  . ALA A 1 562 ? 113.482 135.543 130.132 1.00 228.46 ?  562  ALA A CA  1 
ATOM   3371 C C   . ALA A 1 562 ? 114.247 135.953 128.891 1.00 228.46 ?  562  ALA A C   1 
ATOM   3372 O O   . ALA A 1 562 ? 113.829 136.851 128.192 1.00 228.46 ?  562  ALA A O   1 
ATOM   3373 C CB  . ALA A 1 562 ? 114.188 136.058 131.362 1.00 228.46 ?  562  ALA A CB  1 
ATOM   3374 N N   . VAL A 1 563 ? 115.376 135.313 128.616 1.00 239.08 ?  563  VAL A N   1 
ATOM   3375 C CA  . VAL A 1 563 ? 116.190 135.702 127.471 1.00 239.08 ?  563  VAL A CA  1 
ATOM   3376 C C   . VAL A 1 563 ? 115.460 135.413 126.169 1.00 239.08 ?  563  VAL A C   1 
ATOM   3377 O O   . VAL A 1 563 ? 115.536 136.193 125.238 1.00 239.08 ?  563  VAL A O   1 
ATOM   3378 C CB  . VAL A 1 563 ? 117.602 135.070 127.503 1.00 239.08 ?  563  VAL A CB  1 
ATOM   3379 C CG1 . VAL A 1 563 ? 118.504 135.725 126.476 1.00 239.08 ?  563  VAL A CG1 1 
ATOM   3380 C CG2 . VAL A 1 563 ? 118.226 135.276 128.869 1.00 239.08 ?  563  VAL A CG2 1 
ATOM   3381 N N   . ILE A 1 564 ? 114.717 134.317 126.106 1.00 243.29 ?  564  ILE A N   1 
ATOM   3382 C CA  . ILE A 1 564 ? 113.924 134.031 124.915 1.00 243.29 ?  564  ILE A CA  1 
ATOM   3383 C C   . ILE A 1 564 ? 112.879 135.118 124.738 1.00 243.29 ?  564  ILE A C   1 
ATOM   3384 O O   . ILE A 1 564 ? 112.762 135.687 123.664 1.00 243.29 ?  564  ILE A O   1 
ATOM   3385 C CB  . ILE A 1 564 ? 113.279 132.629 124.979 1.00 243.29 ?  564  ILE A CB  1 
ATOM   3386 C CG1 . ILE A 1 564 ? 114.333 131.557 124.712 1.00 243.29 ?  564  ILE A CG1 1 
ATOM   3387 C CG2 . ILE A 1 564 ? 112.144 132.479 123.980 1.00 243.29 ?  564  ILE A CG2 1 
ATOM   3388 C CD1 . ILE A 1 564 ? 113.955 130.189 125.234 1.00 243.29 ?  564  ILE A CD1 1 
ATOM   3389 N N   . LEU A 1 565 ? 112.155 135.448 125.798 1.00 267.30 ?  565  LEU A N   1 
ATOM   3390 C CA  . LEU A 1 565 ? 111.153 136.505 125.729 1.00 267.30 ?  565  LEU A CA  1 
ATOM   3391 C C   . LEU A 1 565 ? 111.762 137.837 125.356 1.00 267.30 ?  565  LEU A C   1 
ATOM   3392 O O   . LEU A 1 565 ? 111.188 138.575 124.574 1.00 267.30 ?  565  LEU A O   1 
ATOM   3393 C CB  . LEU A 1 565 ? 110.411 136.625 127.054 1.00 267.30 ?  565  LEU A CB  1 
ATOM   3394 C CG  . LEU A 1 565 ? 109.428 135.496 127.329 1.00 267.30 ?  565  LEU A CG  1 
ATOM   3395 C CD1 . LEU A 1 565 ? 108.645 135.777 128.591 1.00 267.30 ?  565  LEU A CD1 1 
ATOM   3396 C CD2 . LEU A 1 565 ? 108.491 135.304 126.152 1.00 267.30 ?  565  LEU A CD2 1 
ATOM   3397 N N   . ALA A 1 566 ? 112.928 138.146 125.903 1.00 262.27 ?  566  ALA A N   1 
ATOM   3398 C CA  . ALA A 1 566 ? 113.608 139.387 125.590 1.00 262.27 ?  566  ALA A CA  1 
ATOM   3399 C C   . ALA A 1 566 ? 113.945 139.431 124.136 1.00 262.27 ?  566  ALA A C   1 
ATOM   3400 O O   . ALA A 1 566 ? 113.647 140.405 123.465 1.00 262.27 ?  566  ALA A O   1 
ATOM   3401 C CB  . ALA A 1 566 ? 114.871 139.499 126.409 1.00 262.27 ?  566  ALA A CB  1 
ATOM   3402 N N   . ASN A 1 567 ? 114.565 138.371 123.642 1.00 256.31 ?  567  ASN A N   1 
ATOM   3403 C CA  . ASN A 1 567 ? 114.936 138.300 122.244 1.00 256.31 ?  567  ASN A CA  1 
ATOM   3404 C C   . ASN A 1 567 ? 113.719 138.500 121.385 1.00 256.31 ?  567  ASN A C   1 
ATOM   3405 O O   . ASN A 1 567 ? 113.743 139.311 120.490 1.00 256.31 ?  567  ASN A O   1 
ATOM   3406 C CB  . ASN A 1 567 ? 115.549 136.945 121.933 1.00 256.31 ?  567  ASN A CB  1 
ATOM   3407 C CG  . ASN A 1 567 ? 117.044 136.927 122.101 1.00 256.31 ?  567  ASN A CG  1 
ATOM   3408 O OD1 . ASN A 1 567 ? 117.771 136.657 121.155 1.00 256.31 ?  567  ASN A OD1 1 
ATOM   3409 N ND2 . ASN A 1 567 ? 117.511 137.195 123.309 1.00 256.31 ?  567  ASN A ND2 1 
ATOM   3410 N N   . MET A 1 568 ? 112.650 137.772 121.663 1.00 259.23 ?  568  MET A N   1 
ATOM   3411 C CA  . MET A 1 568 ? 111.421 137.900 120.895 1.00 259.23 ?  568  MET A CA  1 
ATOM   3412 C C   . MET A 1 568 ? 110.933 139.331 120.800 1.00 259.23 ?  568  MET A C   1 
ATOM   3413 O O   . MET A 1 568 ? 110.756 139.852 119.704 1.00 259.23 ?  568  MET A O   1 
ATOM   3414 C CB  . MET A 1 568 ? 110.331 137.033 121.508 1.00 259.23 ?  568  MET A CB  1 
ATOM   3415 C CG  . MET A 1 568 ? 110.453 135.558 121.179 1.00 259.23 ?  568  MET A CG  1 
ATOM   3416 S SD  . MET A 1 568 ? 109.287 134.592 122.150 1.00 259.23 ?  568  MET A SD  1 
ATOM   3417 C CE  . MET A 1 568 ? 107.987 135.802 122.368 1.00 259.23 ?  568  MET A CE  1 
ATOM   3418 N N   . VAL A 1 569 ? 110.714 139.973 121.940 1.00 227.12 ?  569  VAL A N   1 
ATOM   3419 C CA  . VAL A 1 569 ? 110.266 141.359 121.948 1.00 227.12 ?  569  VAL A CA  1 
ATOM   3420 C C   . VAL A 1 569 ? 111.228 142.269 121.188 1.00 227.12 ?  569  VAL A C   1 
ATOM   3421 O O   . VAL A 1 569 ? 110.816 143.023 120.316 1.00 227.12 ?  569  VAL A O   1 
ATOM   3422 C CB  . VAL A 1 569 ? 110.035 141.869 123.385 1.00 227.12 ?  569  VAL A CB  1 
ATOM   3423 C CG1 . VAL A 1 569 ? 109.562 143.308 123.378 1.00 227.12 ?  569  VAL A CG1 1 
ATOM   3424 C CG2 . VAL A 1 569 ? 109.005 141.004 124.085 1.00 227.12 ?  569  VAL A CG2 1 
ATOM   3425 N N   . ALA A 1 570 ? 112.516 142.175 121.480 1.00 244.26 ?  570  ALA A N   1 
ATOM   3426 C CA  . ALA A 1 570 ? 113.483 143.047 120.832 1.00 244.26 ?  570  ALA A CA  1 
ATOM   3427 C C   . ALA A 1 570 ? 113.612 142.808 119.342 1.00 244.26 ?  570  ALA A C   1 
ATOM   3428 O O   . ALA A 1 570 ? 113.781 143.752 118.589 1.00 244.26 ?  570  ALA A O   1 
ATOM   3429 C CB  . ALA A 1 570 ? 114.829 142.907 121.491 1.00 244.26 ?  570  ALA A CB  1 
ATOM   3430 N N   . GLN A 1 571 ? 113.531 141.556 118.908 1.00 249.88 ?  571  GLN A N   1 
ATOM   3431 C CA  . GLN A 1 571 ? 113.623 141.234 117.492 1.00 249.88 ?  571  GLN A CA  1 
ATOM   3432 C C   . GLN A 1 571 ? 112.405 141.744 116.759 1.00 249.88 ?  571  GLN A C   1 
ATOM   3433 O O   . GLN A 1 571 ? 112.473 142.050 115.574 1.00 249.88 ?  571  GLN A O   1 
ATOM   3434 C CB  . GLN A 1 571 ? 113.753 139.732 117.287 1.00 249.88 ?  571  GLN A CB  1 
ATOM   3435 C CG  . GLN A 1 571 ? 115.174 139.242 117.097 1.00 249.88 ?  571  GLN A CG  1 
ATOM   3436 C CD  . GLN A 1 571 ? 115.487 138.029 117.945 1.00 249.88 ?  571  GLN A CD  1 
ATOM   3437 O OE1 . GLN A 1 571 ? 116.618 137.844 118.390 1.00 249.88 ?  571  GLN A OE1 1 
ATOM   3438 N NE2 . GLN A 1 571 ? 114.482 137.195 118.174 1.00 249.88 ?  571  GLN A NE2 1 
ATOM   3439 N N   . SER A 1 572 ? 111.286 141.853 117.459 1.00 280.35 ?  572  SER A N   1 
ATOM   3440 C CA  . SER A 1 572 ? 110.074 142.374 116.854 1.00 280.35 ?  572  SER A CA  1 
ATOM   3441 C C   . SER A 1 572 ? 110.047 143.896 116.855 1.00 280.35 ?  572  SER A C   1 
ATOM   3442 O O   . SER A 1 572 ? 109.116 144.498 116.329 1.00 280.35 ?  572  SER A O   1 
ATOM   3443 C CB  . SER A 1 572 ? 108.849 141.835 117.589 1.00 280.35 ?  572  SER A CB  1 
ATOM   3444 O OG  . SER A 1 572 ? 108.499 142.668 118.678 1.00 280.35 ?  572  SER A OG  1 
ATOM   3445 N N   . LEU A 1 573 ? 111.057 144.522 117.444 1.00 229.04 ?  573  LEU A N   1 
ATOM   3446 C CA  . LEU A 1 573 ? 111.086 145.974 117.520 1.00 229.04 ?  573  LEU A CA  1 
ATOM   3447 C C   . LEU A 1 573 ? 112.254 146.605 116.777 1.00 229.04 ?  573  LEU A C   1 
ATOM   3448 O O   . LEU A 1 573 ? 112.057 147.238 115.747 1.00 229.04 ?  573  LEU A O   1 
ATOM   3449 C CB  . LEU A 1 573 ? 111.086 146.428 118.974 1.00 229.04 ?  573  LEU A CB  1 
ATOM   3450 C CG  . LEU A 1 573 ? 109.823 146.198 119.797 1.00 229.04 ?  573  LEU A CG  1 
ATOM   3451 C CD1 . LEU A 1 573 ? 110.080 146.552 121.252 1.00 229.04 ?  573  LEU A CD1 1 
ATOM   3452 C CD2 . LEU A 1 573 ? 108.663 147.005 119.240 1.00 229.04 ?  573  LEU A CD2 1 
ATOM   3453 N N   . GLN A 1 574 ? 113.468 146.450 117.288 1.00 226.72 ?  574  GLN A N   1 
ATOM   3454 C CA  . GLN A 1 574 ? 114.626 147.096 116.674 1.00 226.72 ?  574  GLN A CA  1 
ATOM   3455 C C   . GLN A 1 574 ? 115.650 146.068 116.245 1.00 226.72 ?  574  GLN A C   1 
ATOM   3456 O O   . GLN A 1 574 ? 115.496 144.896 116.546 1.00 226.72 ?  574  GLN A O   1 
ATOM   3457 C CB  . GLN A 1 574 ? 115.263 148.090 117.660 1.00 226.72 ?  574  GLN A CB  1 
ATOM   3458 C CG  . GLN A 1 574 ? 114.442 149.334 117.966 1.00 226.72 ?  574  GLN A CG  1 
ATOM   3459 C CD  . GLN A 1 574 ? 113.905 150.030 116.733 1.00 226.72 ?  574  GLN A CD  1 
ATOM   3460 O OE1 . GLN A 1 574 ? 114.653 150.390 115.829 1.00 226.72 ?  574  GLN A OE1 1 
ATOM   3461 N NE2 . GLN A 1 574 ? 112.595 150.237 116.701 1.00 226.72 ?  574  GLN A NE2 1 
ATOM   3462 N N   . PRO A 1 575 ? 116.691 146.489 115.503 1.00 270.67 ?  575  PRO A N   1 
ATOM   3463 C CA  . PRO A 1 575 ? 117.750 145.523 115.194 1.00 270.67 ?  575  PRO A CA  1 
ATOM   3464 C C   . PRO A 1 575 ? 118.656 145.239 116.385 1.00 270.67 ?  575  PRO A C   1 
ATOM   3465 O O   . PRO A 1 575 ? 118.390 145.670 117.501 1.00 270.67 ?  575  PRO A O   1 
ATOM   3466 C CB  . PRO A 1 575 ? 118.560 146.232 114.113 1.00 270.67 ?  575  PRO A CB  1 
ATOM   3467 C CG  . PRO A 1 575 ? 117.613 147.177 113.478 1.00 270.67 ?  575  PRO A CG  1 
ATOM   3468 C CD  . PRO A 1 575 ? 116.727 147.644 114.585 1.00 270.67 ?  575  PRO A CD  1 
ATOM   3469 N N   . SER A 1 576 ? 119.731 144.502 116.157 1.00 286.08 ?  576  SER A N   1 
ATOM   3470 C CA  . SER A 1 576 ? 120.675 144.253 117.227 1.00 286.08 ?  576  SER A CA  1 
ATOM   3471 C C   . SER A 1 576 ? 121.598 145.446 117.270 1.00 286.08 ?  576  SER A C   1 
ATOM   3472 O O   . SER A 1 576 ? 121.654 146.205 116.320 1.00 286.08 ?  576  SER A O   1 
ATOM   3473 C CB  . SER A 1 576 ? 121.464 142.979 116.957 1.00 286.08 ?  576  SER A CB  1 
ATOM   3474 O OG  . SER A 1 576 ? 122.716 143.265 116.366 1.00 286.08 ?  576  SER A OG  1 
ATOM   3475 N N   . LEU A 1 577 ? 122.325 145.622 118.364 1.00 272.66 ?  577  LEU A N   1 
ATOM   3476 C CA  . LEU A 1 577 ? 123.270 146.721 118.467 1.00 272.66 ?  577  LEU A CA  1 
ATOM   3477 C C   . LEU A 1 577 ? 124.206 146.674 117.294 1.00 272.66 ?  577  LEU A C   1 
ATOM   3478 O O   . LEU A 1 577 ? 124.390 147.668 116.615 1.00 272.66 ?  577  LEU A O   1 
ATOM   3479 C CB  . LEU A 1 577 ? 124.079 146.624 119.756 1.00 272.66 ?  577  LEU A CB  1 
ATOM   3480 C CG  . LEU A 1 577 ? 124.164 147.879 120.626 1.00 272.66 ?  577  LEU A CG  1 
ATOM   3481 C CD1 . LEU A 1 577 ? 125.609 148.292 120.852 1.00 272.66 ?  577  LEU A CD1 1 
ATOM   3482 C CD2 . LEU A 1 577 ? 123.358 149.025 120.042 1.00 272.66 ?  577  LEU A CD2 1 
ATOM   3483 N N   . TYR A 1 578 ? 124.712 145.486 116.997 1.00 288.67 ?  578  TYR A N   1 
ATOM   3484 C CA  . TYR A 1 578 ? 125.662 145.308 115.907 1.00 288.67 ?  578  TYR A CA  1 
ATOM   3485 C C   . TYR A 1 578 ? 125.096 145.601 114.533 1.00 288.67 ?  578  TYR A C   1 
ATOM   3486 O O   . TYR A 1 578 ? 125.706 146.324 113.757 1.00 288.67 ?  578  TYR A O   1 
ATOM   3487 C CB  . TYR A 1 578 ? 126.205 143.888 115.973 1.00 288.67 ?  578  TYR A CB  1 
ATOM   3488 C CG  . TYR A 1 578 ? 126.714 143.556 117.348 1.00 288.67 ?  578  TYR A CG  1 
ATOM   3489 C CD1 . TYR A 1 578 ? 127.558 144.430 118.004 1.00 288.67 ?  578  TYR A CD1 1 
ATOM   3490 C CD2 . TYR A 1 578 ? 126.335 142.393 118.004 1.00 288.67 ?  578  TYR A CD2 1 
ATOM   3491 C CE1 . TYR A 1 578 ? 128.027 144.159 119.264 1.00 288.67 ?  578  TYR A CE1 1 
ATOM   3492 C CE2 . TYR A 1 578 ? 126.806 142.113 119.275 1.00 288.67 ?  578  TYR A CE2 1 
ATOM   3493 C CZ  . TYR A 1 578 ? 127.651 143.011 119.896 1.00 288.67 ?  578  TYR A CZ  1 
ATOM   3494 O OH  . TYR A 1 578 ? 128.162 142.787 121.150 1.00 288.67 ?  578  TYR A OH  1 
ATOM   3495 N N   . ASP A 1 579 ? 123.930 145.051 114.231 1.00 309.79 ?  579  ASP A N   1 
ATOM   3496 C CA  . ASP A 1 579 ? 123.319 145.268 112.929 1.00 309.79 ?  579  ASP A CA  1 
ATOM   3497 C C   . ASP A 1 579 ? 122.874 146.704 112.745 1.00 309.79 ?  579  ASP A C   1 
ATOM   3498 O O   . ASP A 1 579 ? 122.909 147.219 111.637 1.00 309.79 ?  579  ASP A O   1 
ATOM   3499 C CB  . ASP A 1 579 ? 122.149 144.316 112.717 1.00 309.79 ?  579  ASP A CB  1 
ATOM   3500 C CG  . ASP A 1 579 ? 122.596 142.882 112.545 1.00 309.79 ?  579  ASP A CG  1 
ATOM   3501 O OD1 . ASP A 1 579 ? 123.209 142.572 111.504 1.00 309.79 ?  579  ASP A OD1 1 
ATOM   3502 O OD2 . ASP A 1 579 ? 122.342 142.067 113.455 1.00 309.79 -1 579  ASP A OD2 1 
ATOM   3503 N N   . SER A 1 580 ? 122.463 147.358 113.822 1.00 294.72 ?  580  SER A N   1 
ATOM   3504 C CA  . SER A 1 580 ? 122.078 148.758 113.737 1.00 294.72 ?  580  SER A CA  1 
ATOM   3505 C C   . SER A 1 580 ? 123.290 149.627 113.474 1.00 294.72 ?  580  SER A C   1 
ATOM   3506 O O   . SER A 1 580 ? 123.201 150.614 112.756 1.00 294.72 ?  580  SER A O   1 
ATOM   3507 C CB  . SER A 1 580 ? 121.376 149.207 115.013 1.00 294.72 ?  580  SER A CB  1 
ATOM   3508 O OG  . SER A 1 580 ? 122.233 149.984 115.828 1.00 294.72 ?  580  SER A OG  1 
ATOM   3509 N N   . ILE A 1 581 ? 124.424 149.270 114.058 1.00 282.70 ?  581  ILE A N   1 
ATOM   3510 C CA  . ILE A 1 581 ? 125.642 150.028 113.831 1.00 282.70 ?  581  ILE A CA  1 
ATOM   3511 C C   . ILE A 1 581 ? 126.047 149.819 112.392 1.00 282.70 ?  581  ILE A C   1 
ATOM   3512 O O   . ILE A 1 581 ? 126.409 150.771 111.712 1.00 282.70 ?  581  ILE A O   1 
ATOM   3513 C CB  . ILE A 1 581 ? 126.754 149.620 114.806 1.00 282.70 ?  581  ILE A CB  1 
ATOM   3514 C CG1 . ILE A 1 581 ? 126.522 150.312 116.141 1.00 282.70 ?  581  ILE A CG1 1 
ATOM   3515 C CG2 . ILE A 1 581 ? 128.125 149.999 114.272 1.00 282.70 ?  581  ILE A CG2 1 
ATOM   3516 C CD1 . ILE A 1 581 ? 127.011 149.518 117.320 1.00 282.70 ?  581  ILE A CD1 1 
ATOM   3517 N N   . ILE A 1 582 ? 125.976 148.584 111.917 1.00 277.28 ?  582  ILE A N   1 
ATOM   3518 C CA  . ILE A 1 582 ? 126.250 148.327 110.505 1.00 277.28 ?  582  ILE A CA  1 
ATOM   3519 C C   . ILE A 1 582 ? 125.481 149.315 109.640 1.00 277.28 ?  582  ILE A C   1 
ATOM   3520 O O   . ILE A 1 582 ? 126.060 149.941 108.757 1.00 277.28 ?  582  ILE A O   1 
ATOM   3521 C CB  . ILE A 1 582 ? 125.919 146.868 110.122 1.00 277.28 ?  582  ILE A CB  1 
ATOM   3522 C CG1 . ILE A 1 582 ? 127.013 145.928 110.620 1.00 277.28 ?  582  ILE A CG1 1 
ATOM   3523 C CG2 . ILE A 1 582 ? 125.749 146.696 108.621 1.00 277.28 ?  582  ILE A CG2 1 
ATOM   3524 C CD1 . ILE A 1 582 ? 126.532 144.527 110.903 1.00 277.28 ?  582  ILE A CD1 1 
ATOM   3525 N N   . GLN A 1 583 ? 124.194 149.494 109.912 1.00 314.83 ?  583  GLN A N   1 
ATOM   3526 C CA  . GLN A 1 583 ? 123.393 150.451 109.161 1.00 314.83 ?  583  GLN A CA  1 
ATOM   3527 C C   . GLN A 1 583 ? 123.938 151.872 109.242 1.00 314.83 ?  583  GLN A C   1 
ATOM   3528 O O   . GLN A 1 583 ? 124.124 152.519 108.217 1.00 314.83 ?  583  GLN A O   1 
ATOM   3529 C CB  . GLN A 1 583 ? 121.950 150.425 109.650 1.00 314.83 ?  583  GLN A CB  1 
ATOM   3530 C CG  . GLN A 1 583 ? 121.236 149.111 109.407 1.00 314.83 ?  583  GLN A CG  1 
ATOM   3531 C CD  . GLN A 1 583 ? 120.299 148.744 110.540 1.00 314.83 ?  583  GLN A CD  1 
ATOM   3532 O OE1 . GLN A 1 583 ? 119.783 149.614 111.241 1.00 314.83 ?  583  GLN A OE1 1 
ATOM   3533 N NE2 . GLN A 1 583 ? 120.083 147.449 110.731 1.00 314.83 ?  583  GLN A NE2 1 
ATOM   3534 N N   . VAL A 1 584 ? 124.185 152.365 110.451 1.00 286.70 ?  584  VAL A N   1 
ATOM   3535 C CA  . VAL A 1 584 ? 124.705 153.719 110.629 1.00 286.70 ?  584  VAL A CA  1 
ATOM   3536 C C   . VAL A 1 584 ? 126.046 153.883 109.938 1.00 286.70 ?  584  VAL A C   1 
ATOM   3537 O O   . VAL A 1 584 ? 126.248 154.831 109.182 1.00 286.70 ?  584  VAL A O   1 
ATOM   3538 C CB  . VAL A 1 584 ? 124.855 154.078 112.124 1.00 286.70 ?  584  VAL A CB  1 
ATOM   3539 C CG1 . VAL A 1 584 ? 125.374 155.496 112.294 1.00 286.70 ?  584  VAL A CG1 1 
ATOM   3540 C CG2 . VAL A 1 584 ? 123.526 153.937 112.837 1.00 286.70 ?  584  VAL A CG2 1 
ATOM   3541 N N   . LYS A 1 585 ? 126.956 152.940 110.161 1.00 267.69 ?  585  LYS A N   1 
ATOM   3542 C CA  . LYS A 1 585 ? 128.293 153.004 109.568 1.00 267.69 ?  585  LYS A CA  1 
ATOM   3543 C C   . LYS A 1 585 ? 128.312 152.601 108.108 1.00 267.69 ?  585  LYS A C   1 
ATOM   3544 O O   . LYS A 1 585 ? 129.392 152.523 107.523 1.00 267.69 ?  585  LYS A O   1 
ATOM   3545 C CB  . LYS A 1 585 ? 129.250 152.103 110.339 1.00 267.69 ?  585  LYS A CB  1 
ATOM   3546 C CG  . LYS A 1 585 ? 129.671 152.646 111.691 1.00 267.69 ?  585  LYS A CG  1 
ATOM   3547 C CD  . LYS A 1 585 ? 130.923 151.942 112.185 1.00 267.69 ?  585  LYS A CD  1 
ATOM   3548 C CE  . LYS A 1 585 ? 131.358 152.475 113.540 1.00 267.69 ?  585  LYS A CE  1 
ATOM   3549 N NZ  . LYS A 1 585 ? 132.436 151.647 114.147 1.00 267.69 1  585  LYS A NZ  1 
ATOM   3550 N N   . LYS A 1 586 ? 127.144 152.339 107.526 1.00 276.08 ?  586  LYS A N   1 
ATOM   3551 C CA  . LYS A 1 586 ? 127.037 151.964 106.115 1.00 276.08 ?  586  LYS A CA  1 
ATOM   3552 C C   . LYS A 1 586 ? 128.035 150.891 105.745 1.00 276.08 ?  586  LYS A C   1 
ATOM   3553 O O   . LYS A 1 586 ? 128.712 150.985 104.723 1.00 276.08 ?  586  LYS A O   1 
ATOM   3554 C CB  . LYS A 1 586 ? 127.162 153.190 105.205 1.00 276.08 ?  586  LYS A CB  1 
ATOM   3555 C CG  . LYS A 1 586 ? 125.944 154.098 105.226 1.00 276.08 ?  586  LYS A CG  1 
ATOM   3556 C CD  . LYS A 1 586 ? 126.290 155.503 105.700 1.00 276.08 ?  586  LYS A CD  1 
ATOM   3557 C CE  . LYS A 1 586 ? 127.792 155.726 105.779 1.00 276.08 ?  586  LYS A CE  1 
ATOM   3558 N NZ  . LYS A 1 586 ? 128.225 156.107 107.151 1.00 276.08 1  586  LYS A NZ  1 
ATOM   3559 N N   . LEU A 1 587 ? 128.131 149.865 106.578 1.00 300.88 ?  587  LEU A N   1 
ATOM   3560 C CA  . LEU A 1 587 ? 129.048 148.780 106.304 1.00 300.88 ?  587  LEU A CA  1 
ATOM   3561 C C   . LEU A 1 587 ? 128.445 147.946 105.200 1.00 300.88 ?  587  LEU A C   1 
ATOM   3562 O O   . LEU A 1 587 ? 127.255 147.640 105.253 1.00 300.88 ?  587  LEU A O   1 
ATOM   3563 C CB  . LEU A 1 587 ? 129.279 147.959 107.568 1.00 300.88 ?  587  LEU A CB  1 
ATOM   3564 C CG  . LEU A 1 587 ? 130.234 148.641 108.542 1.00 300.88 ?  587  LEU A CG  1 
ATOM   3565 C CD1 . LEU A 1 587 ? 129.985 148.191 109.969 1.00 300.88 ?  587  LEU A CD1 1 
ATOM   3566 C CD2 . LEU A 1 587 ? 131.675 148.390 108.134 1.00 300.88 ?  587  LEU A CD2 1 
ATOM   3567 N N   . PRO A 1 588 ? 129.249 147.592 104.185 1.00 320.95 ?  588  PRO A N   1 
ATOM   3568 C CA  . PRO A 1 588 ? 128.750 146.831 103.032 1.00 320.95 ?  588  PRO A CA  1 
ATOM   3569 C C   . PRO A 1 588 ? 127.821 145.699 103.410 1.00 320.95 ?  588  PRO A C   1 
ATOM   3570 O O   . PRO A 1 588 ? 126.679 145.710 102.942 1.00 320.95 ?  588  PRO A O   1 
ATOM   3571 C CB  . PRO A 1 588 ? 130.024 146.261 102.436 1.00 320.95 ?  588  PRO A CB  1 
ATOM   3572 C CG  . PRO A 1 588 ? 131.075 147.265 102.764 1.00 320.95 ?  588  PRO A CG  1 
ATOM   3573 C CD  . PRO A 1 588 ? 130.679 147.920 104.055 1.00 320.95 ?  588  PRO A CD  1 
ATOM   3574 N N   . TYR A 1 589 ? 128.298 144.733 104.191 1.00 335.86 ?  589  TYR A N   1 
ATOM   3575 C CA  . TYR A 1 589 ? 127.461 143.631 104.669 1.00 335.86 ?  589  TYR A CA  1 
ATOM   3576 C C   . TYR A 1 589 ? 126.733 142.856 103.582 1.00 335.86 ?  589  TYR A C   1 
ATOM   3577 O O   . TYR A 1 589 ? 127.215 142.792 102.448 1.00 335.86 ?  589  TYR A O   1 
ATOM   3578 C CB  . TYR A 1 589 ? 126.466 144.147 105.723 1.00 335.86 ?  589  TYR A CB  1 
ATOM   3579 C CG  . TYR A 1 589 ? 126.165 143.176 106.832 1.00 335.86 ?  589  TYR A CG  1 
ATOM   3580 C CD1 . TYR A 1 589 ? 127.179 142.492 107.470 1.00 335.86 ?  589  TYR A CD1 1 
ATOM   3581 C CD2 . TYR A 1 589 ? 124.857 142.935 107.227 1.00 335.86 ?  589  TYR A CD2 1 
ATOM   3582 C CE1 . TYR A 1 589 ? 126.902 141.601 108.479 1.00 335.86 ?  589  TYR A CE1 1 
ATOM   3583 C CE2 . TYR A 1 589 ? 124.571 142.041 108.235 1.00 335.86 ?  589  TYR A CE2 1 
ATOM   3584 C CZ  . TYR A 1 589 ? 125.600 141.377 108.857 1.00 335.86 ?  589  TYR A CZ  1 
ATOM   3585 O OH  . TYR A 1 589 ? 125.323 140.485 109.861 1.00 335.86 ?  589  TYR A OH  1 
ATOM   3586 N N   . GLY B 1 115 ? 104.264 132.971 114.963 1.00 307.19 ?  115  GLY B N   1 
ATOM   3587 C CA  . GLY B 1 115 ? 103.865 132.481 113.658 1.00 307.19 ?  115  GLY B CA  1 
ATOM   3588 C C   . GLY B 1 115 ? 103.585 131.000 113.729 1.00 307.19 ?  115  GLY B C   1 
ATOM   3589 O O   . GLY B 1 115 ? 103.604 130.430 114.810 1.00 307.19 ?  115  GLY B O   1 
ATOM   3590 N N   . GLU B 1 116 ? 103.321 130.374 112.587 1.00 330.29 ?  116  GLU B N   1 
ATOM   3591 C CA  . GLU B 1 116 ? 103.019 128.943 112.560 1.00 330.29 ?  116  GLU B CA  1 
ATOM   3592 C C   . GLU B 1 116 ? 104.195 128.125 113.061 1.00 330.29 ?  116  GLU B C   1 
ATOM   3593 O O   . GLU B 1 116 ? 104.007 127.092 113.696 1.00 330.29 ?  116  GLU B O   1 
ATOM   3594 C CB  . GLU B 1 116 ? 102.616 128.487 111.159 1.00 330.29 ?  116  GLU B CB  1 
ATOM   3595 C CG  . GLU B 1 116 ? 101.429 127.535 111.151 1.00 330.29 ?  116  GLU B CG  1 
ATOM   3596 C CD  . GLU B 1 116 ? 101.780 126.151 110.633 1.00 330.29 ?  116  GLU B CD  1 
ATOM   3597 O OE1 . GLU B 1 116 ? 102.838 125.611 111.021 1.00 330.29 ?  116  GLU B OE1 1 
ATOM   3598 O OE2 . GLU B 1 116 ? 100.989 125.602 109.839 1.00 330.29 ?  116  GLU B OE2 1 
ATOM   3599 N N   . ASP B 1 117 ? 105.410 128.587 112.788 1.00 314.50 ?  117  ASP B N   1 
ATOM   3600 C CA  . ASP B 1 117 ? 106.587 127.884 113.282 1.00 314.50 ?  117  ASP B CA  1 
ATOM   3601 C C   . ASP B 1 117 ? 106.704 128.011 114.790 1.00 314.50 ?  117  ASP B C   1 
ATOM   3602 O O   . ASP B 1 117 ? 107.161 127.093 115.436 1.00 314.50 ?  117  ASP B O   1 
ATOM   3603 C CB  . ASP B 1 117 ? 107.873 128.344 112.580 1.00 314.50 ?  117  ASP B CB  1 
ATOM   3604 C CG  . ASP B 1 117 ? 108.419 129.643 113.138 1.00 314.50 ?  117  ASP B CG  1 
ATOM   3605 O OD1 . ASP B 1 117 ? 107.782 130.698 112.923 1.00 314.50 ?  117  ASP B OD1 1 
ATOM   3606 O OD2 . ASP B 1 117 ? 109.479 129.611 113.796 1.00 314.50 ?  117  ASP B OD2 1 
ATOM   3607 N N   . GLY B 1 118 ? 106.268 129.128 115.357 1.00 305.92 ?  118  GLY B N   1 
ATOM   3608 C CA  . GLY B 1 118 ? 106.299 129.292 116.795 1.00 305.92 ?  118  GLY B CA  1 
ATOM   3609 C C   . GLY B 1 118 ? 105.345 128.326 117.451 1.00 305.92 ?  118  GLY B C   1 
ATOM   3610 O O   . GLY B 1 118 ? 105.648 127.785 118.508 1.00 305.92 ?  118  GLY B O   1 
ATOM   3611 N N   . ILE B 1 119 ? 104.195 128.099 116.825 1.00 303.10 ?  119  ILE B N   1 
ATOM   3612 C CA  . ILE B 1 119 ? 103.235 127.141 117.349 1.00 303.10 ?  119  ILE B CA  1 
ATOM   3613 C C   . ILE B 1 119 ? 103.826 125.753 117.228 1.00 303.10 ?  119  ILE B C   1 
ATOM   3614 O O   . ILE B 1 119 ? 103.683 124.943 118.128 1.00 303.10 ?  119  ILE B O   1 
ATOM   3615 C CB  . ILE B 1 119 ? 101.897 127.209 116.590 1.00 303.10 ?  119  ILE B CB  1 
ATOM   3616 C CG1 . ILE B 1 119 ? 101.398 128.647 116.518 1.00 303.10 ?  119  ILE B CG1 1 
ATOM   3617 C CG2 . ILE B 1 119 ? 100.836 126.355 117.265 1.00 303.10 ?  119  ILE B CG2 1 
ATOM   3618 C CD1 . ILE B 1 119 ? 100.324 128.863 115.476 1.00 303.10 ?  119  ILE B CD1 1 
ATOM   3619 N N   . PHE B 1 120 ? 104.511 125.481 116.126 1.00 314.42 ?  120  PHE B N   1 
ATOM   3620 C CA  . PHE B 1 120 ? 105.165 124.192 115.955 1.00 314.42 ?  120  PHE B CA  1 
ATOM   3621 C C   . PHE B 1 120 ? 106.113 123.910 117.108 1.00 314.42 ?  120  PHE B C   1 
ATOM   3622 O O   . PHE B 1 120 ? 106.101 122.819 117.653 1.00 314.42 ?  120  PHE B O   1 
ATOM   3623 C CB  . PHE B 1 120 ? 105.887 124.137 114.607 1.00 314.42 ?  120  PHE B CB  1 
ATOM   3624 C CG  . PHE B 1 120 ? 106.781 122.945 114.432 1.00 314.42 ?  120  PHE B CG  1 
ATOM   3625 C CD1 . PHE B 1 120 ? 106.247 121.684 114.245 1.00 314.42 ?  120  PHE B CD1 1 
ATOM   3626 C CD2 . PHE B 1 120 ? 108.160 123.092 114.432 1.00 314.42 ?  120  PHE B CD2 1 
ATOM   3627 C CE1 . PHE B 1 120 ? 107.069 120.590 114.076 1.00 314.42 ?  120  PHE B CE1 1 
ATOM   3628 C CE2 . PHE B 1 120 ? 108.987 122.001 114.267 1.00 314.42 ?  120  PHE B CE2 1 
ATOM   3629 C CZ  . PHE B 1 120 ? 108.439 120.749 114.087 1.00 314.42 ?  120  PHE B CZ  1 
ATOM   3630 N N   . LEU B 1 121 ? 106.913 124.894 117.497 1.00 306.71 ?  121  LEU B N   1 
ATOM   3631 C CA  . LEU B 1 121 ? 107.862 124.709 118.587 1.00 306.71 ?  121  LEU B CA  1 
ATOM   3632 C C   . LEU B 1 121 ? 107.183 124.576 119.942 1.00 306.71 ?  121  LEU B C   1 
ATOM   3633 O O   . LEU B 1 121 ? 107.643 123.831 120.796 1.00 306.71 ?  121  LEU B O   1 
ATOM   3634 C CB  . LEU B 1 121 ? 108.866 125.855 118.615 1.00 306.71 ?  121  LEU B CB  1 
ATOM   3635 C CG  . LEU B 1 121 ? 109.545 126.222 117.304 1.00 306.71 ?  121  LEU B CG  1 
ATOM   3636 C CD1 . LEU B 1 121 ? 110.222 127.577 117.380 1.00 306.71 ?  121  LEU B CD1 1 
ATOM   3637 C CD2 . LEU B 1 121 ? 110.494 125.142 116.835 1.00 306.71 ?  121  LEU B CD2 1 
ATOM   3638 N N   . VAL B 1 122 ? 106.091 125.295 120.148 1.00 300.11 ?  122  VAL B N   1 
ATOM   3639 C CA  . VAL B 1 122 ? 105.348 125.175 121.396 1.00 300.11 ?  122  VAL B CA  1 
ATOM   3640 C C   . VAL B 1 122 ? 104.778 123.771 121.463 1.00 300.11 ?  122  VAL B C   1 
ATOM   3641 O O   . VAL B 1 122 ? 104.897 123.098 122.480 1.00 300.11 ?  122  VAL B O   1 
ATOM   3642 C CB  . VAL B 1 122 ? 104.240 126.248 121.490 1.00 300.11 ?  122  VAL B CB  1 
ATOM   3643 C CG1 . VAL B 1 122 ? 103.046 125.780 122.308 1.00 300.11 ?  122  VAL B CG1 1 
ATOM   3644 C CG2 . VAL B 1 122 ? 104.801 127.534 122.069 1.00 300.11 ?  122  VAL B CG2 1 
ATOM   3645 N N   . LEU B 1 123 ? 104.214 123.299 120.358 1.00 294.58 ?  123  LEU B N   1 
ATOM   3646 C CA  . LEU B 1 123 ? 103.642 121.966 120.324 1.00 294.58 ?  123  LEU B CA  1 
ATOM   3647 C C   . LEU B 1 123 ? 104.724 120.932 120.517 1.00 294.58 ?  123  LEU B C   1 
ATOM   3648 O O   . LEU B 1 123 ? 104.520 119.971 121.237 1.00 294.58 ?  123  LEU B O   1 
ATOM   3649 C CB  . LEU B 1 123 ? 102.918 121.733 119.006 1.00 294.58 ?  123  LEU B CB  1 
ATOM   3650 C CG  . LEU B 1 123 ? 101.395 121.646 119.070 1.00 294.58 ?  123  LEU B CG  1 
ATOM   3651 C CD1 . LEU B 1 123 ? 100.958 120.559 120.038 1.00 294.58 ?  123  LEU B CD1 1 
ATOM   3652 C CD2 . LEU B 1 123 ? 100.789 122.984 119.455 1.00 294.58 ?  123  LEU B CD2 1 
ATOM   3653 N N   . LEU B 1 124 ? 105.876 121.127 119.885 1.00 286.31 ?  124  LEU B N   1 
ATOM   3654 C CA  . LEU B 1 124 ? 106.995 120.212 120.055 1.00 286.31 ?  124  LEU B CA  1 
ATOM   3655 C C   . LEU B 1 124 ? 107.315 120.076 121.518 1.00 286.31 ?  124  LEU B C   1 
ATOM   3656 O O   . LEU B 1 124 ? 107.217 118.996 122.069 1.00 286.31 ?  124  LEU B O   1 
ATOM   3657 C CB  . LEU B 1 124 ? 108.238 120.736 119.343 1.00 286.31 ?  124  LEU B CB  1 
ATOM   3658 C CG  . LEU B 1 124 ? 108.513 120.281 117.918 1.00 286.31 ?  124  LEU B CG  1 
ATOM   3659 C CD1 . LEU B 1 124 ? 109.964 119.873 117.756 1.00 286.31 ?  124  LEU B CD1 1 
ATOM   3660 C CD2 . LEU B 1 124 ? 107.597 119.130 117.573 1.00 286.31 ?  124  LEU B CD2 1 
ATOM   3661 N N   . GLY B 1 125 ? 107.693 121.177 122.151 1.00 272.55 ?  125  GLY B N   1 
ATOM   3662 C CA  . GLY B 1 125 ? 108.040 121.148 123.556 1.00 272.55 ?  125  GLY B CA  1 
ATOM   3663 C C   . GLY B 1 125 ? 106.986 120.522 124.427 1.00 272.55 ?  125  GLY B C   1 
ATOM   3664 O O   . GLY B 1 125 ? 107.288 119.642 125.218 1.00 272.55 ?  125  GLY B O   1 
ATOM   3665 N N   . LEU B 1 126 ? 105.744 120.958 124.276 1.00 275.46 ?  126  LEU B N   1 
ATOM   3666 C CA  . LEU B 1 126 ? 104.653 120.415 125.068 1.00 275.46 ?  126  LEU B CA  1 
ATOM   3667 C C   . LEU B 1 126 ? 104.528 118.919 124.904 1.00 275.46 ?  126  LEU B C   1 
ATOM   3668 O O   . LEU B 1 126 ? 104.582 118.189 125.882 1.00 275.46 ?  126  LEU B O   1 
ATOM   3669 C CB  . LEU B 1 126 ? 103.337 121.086 124.678 1.00 275.46 ?  126  LEU B CB  1 
ATOM   3670 C CG  . LEU B 1 126 ? 102.045 120.564 125.296 1.00 275.46 ?  126  LEU B CG  1 
ATOM   3671 C CD1 . LEU B 1 126 ? 101.793 121.215 126.644 1.00 275.46 ?  126  LEU B CD1 1 
ATOM   3672 C CD2 . LEU B 1 126 ? 100.886 120.810 124.345 1.00 275.46 ?  126  LEU B CD2 1 
ATOM   3673 N N   . LEU B 1 127 ? 104.391 118.454 123.671 1.00 310.34 ?  127  LEU B N   1 
ATOM   3674 C CA  . LEU B 1 127 ? 104.180 117.033 123.436 1.00 310.34 ?  127  LEU B CA  1 
ATOM   3675 C C   . LEU B 1 127 ? 105.360 116.199 123.865 1.00 310.34 ?  127  LEU B C   1 
ATOM   3676 O O   . LEU B 1 127 ? 105.185 115.147 124.445 1.00 310.34 ?  127  LEU B O   1 
ATOM   3677 C CB  . LEU B 1 127 ? 103.867 116.765 121.969 1.00 310.34 ?  127  LEU B CB  1 
ATOM   3678 C CG  . LEU B 1 127 ? 102.411 116.926 121.532 1.00 310.34 ?  127  LEU B CG  1 
ATOM   3679 C CD1 . LEU B 1 127 ? 102.028 115.807 120.579 1.00 310.34 ?  127  LEU B CD1 1 
ATOM   3680 C CD2 . LEU B 1 127 ? 101.464 116.954 122.722 1.00 310.34 ?  127  LEU B CD2 1 
ATOM   3681 N N   . MET B 1 128 ? 106.563 116.675 123.586 1.00 291.41 ?  128  MET B N   1 
ATOM   3682 C CA  . MET B 1 128 ? 107.755 115.950 123.977 1.00 291.41 ?  128  MET B CA  1 
ATOM   3683 C C   . MET B 1 128 ? 107.823 115.776 125.470 1.00 291.41 ?  128  MET B C   1 
ATOM   3684 O O   . MET B 1 128 ? 108.077 114.683 125.951 1.00 291.41 ?  128  MET B O   1 
ATOM   3685 C CB  . MET B 1 128 ? 109.012 116.644 123.473 1.00 291.41 ?  128  MET B CB  1 
ATOM   3686 C CG  . MET B 1 128 ? 109.635 115.931 122.295 1.00 291.41 ?  128  MET B CG  1 
ATOM   3687 S SD  . MET B 1 128 ? 108.352 115.325 121.189 1.00 291.41 ?  128  MET B SD  1 
ATOM   3688 C CE  . MET B 1 128 ? 108.295 113.588 121.624 1.00 291.41 ?  128  MET B CE  1 
ATOM   3689 N N   . ALA B 1 129 ? 107.601 116.853 126.205 1.00 293.14 ?  129  ALA B N   1 
ATOM   3690 C CA  . ALA B 1 129 ? 107.666 116.782 127.647 1.00 293.14 ?  129  ALA B CA  1 
ATOM   3691 C C   . ALA B 1 129 ? 106.614 115.848 128.174 1.00 293.14 ?  129  ALA B C   1 
ATOM   3692 O O   . ALA B 1 129 ? 106.879 115.091 129.084 1.00 293.14 ?  129  ALA B O   1 
ATOM   3693 C CB  . ALA B 1 129 ? 107.492 118.150 128.252 1.00 293.14 ?  129  ALA B CB  1 
ATOM   3694 N N   . LEU B 1 130 ? 105.419 115.895 127.602 1.00 300.42 ?  130  LEU B N   1 
ATOM   3695 C CA  . LEU B 1 130 ? 104.344 115.021 128.037 1.00 300.42 ?  130  LEU B CA  1 
ATOM   3696 C C   . LEU B 1 130 ? 104.708 113.571 127.814 1.00 300.42 ?  130  LEU B C   1 
ATOM   3697 O O   . LEU B 1 130 ? 104.611 112.769 128.727 1.00 300.42 ?  130  LEU B O   1 
ATOM   3698 C CB  . LEU B 1 130 ? 103.049 115.357 127.308 1.00 300.42 ?  130  LEU B CB  1 
ATOM   3699 C CG  . LEU B 1 130 ? 102.336 116.619 127.779 1.00 300.42 ?  130  LEU B CG  1 
ATOM   3700 C CD1 . LEU B 1 130 ? 101.125 116.897 126.906 1.00 300.42 ?  130  LEU B CD1 1 
ATOM   3701 C CD2 . LEU B 1 130 ? 101.942 116.503 129.240 1.00 300.42 ?  130  LEU B CD2 1 
ATOM   3702 N N   . VAL B 1 131 ? 105.144 113.234 126.607 1.00 275.05 ?  131  VAL B N   1 
ATOM   3703 C CA  . VAL B 1 131 ? 105.543 111.867 126.292 1.00 275.05 ?  131  VAL B CA  1 
ATOM   3704 C C   . VAL B 1 131 ? 106.717 111.430 127.165 1.00 275.05 ?  131  VAL B C   1 
ATOM   3705 O O   . VAL B 1 131 ? 106.694 110.346 127.735 1.00 275.05 ?  131  VAL B O   1 
ATOM   3706 C CB  . VAL B 1 131 ? 105.858 111.727 124.787 1.00 275.05 ?  131  VAL B CB  1 
ATOM   3707 C CG1 . VAL B 1 131 ? 106.488 110.388 124.465 1.00 275.05 ?  131  VAL B CG1 1 
ATOM   3708 C CG2 . VAL B 1 131 ? 104.588 111.900 123.971 1.00 275.05 ?  131  VAL B CG2 1 
ATOM   3709 N N   . SER B 1 132 ? 107.720 112.284 127.309 1.00 258.77 ?  132  SER B N   1 
ATOM   3710 C CA  . SER B 1 132 ? 108.875 111.962 128.134 1.00 258.77 ?  132  SER B CA  1 
ATOM   3711 C C   . SER B 1 132 ? 108.509 111.739 129.580 1.00 258.77 ?  132  SER B C   1 
ATOM   3712 O O   . SER B 1 132 ? 108.998 110.809 130.207 1.00 258.77 ?  132  SER B O   1 
ATOM   3713 C CB  . SER B 1 132 ? 109.896 113.085 128.067 1.00 258.77 ?  132  SER B CB  1 
ATOM   3714 O OG  . SER B 1 132 ? 110.963 112.846 128.964 1.00 258.77 ?  132  SER B OG  1 
ATOM   3715 N N   . TRP B 1 133 ? 107.662 112.601 130.122 1.00 271.73 ?  133  TRP B N   1 
ATOM   3716 C CA  . TRP B 1 133 ? 107.255 112.467 131.502 1.00 271.73 ?  133  TRP B CA  1 
ATOM   3717 C C   . TRP B 1 133 ? 106.466 111.199 131.673 1.00 271.73 ?  133  TRP B C   1 
ATOM   3718 O O   . TRP B 1 133 ? 106.680 110.479 132.625 1.00 271.73 ?  133  TRP B O   1 
ATOM   3719 C CB  . TRP B 1 133 ? 106.414 113.664 131.942 1.00 271.73 ?  133  TRP B CB  1 
ATOM   3720 C CG  . TRP B 1 133 ? 106.129 113.704 133.400 1.00 271.73 ?  133  TRP B CG  1 
ATOM   3721 C CD1 . TRP B 1 133 ? 106.912 114.242 134.374 1.00 271.73 ?  133  TRP B CD1 1 
ATOM   3722 C CD2 . TRP B 1 133 ? 104.970 113.185 134.057 1.00 271.73 ?  133  TRP B CD2 1 
ATOM   3723 N NE1 . TRP B 1 133 ? 106.316 114.088 135.599 1.00 271.73 ?  133  TRP B NE1 1 
ATOM   3724 C CE2 . TRP B 1 133 ? 105.122 113.440 135.430 1.00 271.73 ?  133  TRP B CE2 1 
ATOM   3725 C CE3 . TRP B 1 133 ? 103.821 112.525 133.616 1.00 271.73 ?  133  TRP B CE3 1 
ATOM   3726 C CZ2 . TRP B 1 133 ? 104.170 113.062 136.361 1.00 271.73 ?  133  TRP B CZ2 1 
ATOM   3727 C CZ3 . TRP B 1 133 ? 102.880 112.149 134.543 1.00 271.73 ?  133  TRP B CZ3 1 
ATOM   3728 C CH2 . TRP B 1 133 ? 103.057 112.419 135.901 1.00 271.73 ?  133  TRP B CH2 1 
ATOM   3729 N N   . SER B 1 134 ? 105.547 110.925 130.758 1.00 256.83 ?  134  SER B N   1 
ATOM   3730 C CA  . SER B 1 134 ? 104.721 109.737 130.856 1.00 256.83 ?  134  SER B CA  1 
ATOM   3731 C C   . SER B 1 134 ? 105.576 108.495 130.849 1.00 256.83 ?  134  SER B C   1 
ATOM   3732 O O   . SER B 1 134 ? 105.372 107.602 131.657 1.00 256.83 ?  134  SER B O   1 
ATOM   3733 C CB  . SER B 1 134 ? 103.723 109.682 129.709 1.00 256.83 ?  134  SER B CB  1 
ATOM   3734 O OG  . SER B 1 134 ? 102.833 110.780 129.763 1.00 256.83 ?  134  SER B OG  1 
ATOM   3735 N N   . MET B 1 135 ? 106.540 108.433 129.942 1.00 225.39 ?  135  MET B N   1 
ATOM   3736 C CA  . MET B 1 135 ? 107.447 107.302 129.899 1.00 225.39 ?  135  MET B CA  1 
ATOM   3737 C C   . MET B 1 135 ? 108.200 107.204 131.196 1.00 225.39 ?  135  MET B C   1 
ATOM   3738 O O   . MET B 1 135 ? 108.203 106.162 131.820 1.00 225.39 ?  135  MET B O   1 
ATOM   3739 C CB  . MET B 1 135 ? 108.436 107.467 128.761 1.00 225.39 ?  135  MET B CB  1 
ATOM   3740 C CG  . MET B 1 135 ? 107.889 107.038 127.420 1.00 225.39 ?  135  MET B CG  1 
ATOM   3741 S SD  . MET B 1 135 ? 109.212 106.554 126.309 1.00 225.39 ?  135  MET B SD  1 
ATOM   3742 C CE  . MET B 1 135 ? 109.057 107.855 125.103 1.00 225.39 ?  135  MET B CE  1 
ATOM   3743 N N   . GLY B 1 136 ? 108.831 108.294 131.610 1.00 217.14 ?  136  GLY B N   1 
ATOM   3744 C CA  . GLY B 1 136 ? 109.572 108.309 132.855 1.00 217.14 ?  136  GLY B CA  1 
ATOM   3745 C C   . GLY B 1 136 ? 108.736 107.873 134.029 1.00 217.14 ?  136  GLY B C   1 
ATOM   3746 O O   . GLY B 1 136 ? 109.218 107.148 134.883 1.00 217.14 ?  136  GLY B O   1 
ATOM   3747 N N   . TYR B 1 137 ? 107.484 108.302 134.073 1.00 223.63 ?  137  TYR B N   1 
ATOM   3748 C CA  . TYR B 1 137 ? 106.586 107.919 135.144 1.00 223.63 ?  137  TYR B CA  1 
ATOM   3749 C C   . TYR B 1 137 ? 106.375 106.425 135.171 1.00 223.63 ?  137  TYR B C   1 
ATOM   3750 O O   . TYR B 1 137 ? 106.631 105.788 136.175 1.00 223.63 ?  137  TYR B O   1 
ATOM   3751 C CB  . TYR B 1 137 ? 105.243 108.613 134.979 1.00 223.63 ?  137  TYR B CB  1 
ATOM   3752 C CG  . TYR B 1 137 ? 104.475 108.708 136.263 1.00 223.63 ?  137  TYR B CG  1 
ATOM   3753 C CD1 . TYR B 1 137 ? 104.952 109.469 137.315 1.00 223.63 ?  137  TYR B CD1 1 
ATOM   3754 C CD2 . TYR B 1 137 ? 103.283 108.024 136.431 1.00 223.63 ?  137  TYR B CD2 1 
ATOM   3755 C CE1 . TYR B 1 137 ? 104.255 109.558 138.498 1.00 223.63 ?  137  TYR B CE1 1 
ATOM   3756 C CE2 . TYR B 1 137 ? 102.579 108.104 137.613 1.00 223.63 ?  137  TYR B CE2 1 
ATOM   3757 C CZ  . TYR B 1 137 ? 103.071 108.874 138.643 1.00 223.63 ?  137  TYR B CZ  1 
ATOM   3758 O OH  . TYR B 1 137 ? 102.375 108.959 139.825 1.00 223.63 ?  137  TYR B OH  1 
ATOM   3759 N N   . VAL B 1 138 ? 105.913 105.858 134.067 1.00 233.63 ?  138  VAL B N   1 
ATOM   3760 C CA  . VAL B 1 138 ? 105.625 104.432 134.031 1.00 233.63 ?  138  VAL B CA  1 
ATOM   3761 C C   . VAL B 1 138 ? 106.888 103.598 134.221 1.00 233.63 ?  138  VAL B C   1 
ATOM   3762 O O   . VAL B 1 138 ? 106.855 102.567 134.878 1.00 233.63 ?  138  VAL B O   1 
ATOM   3763 C CB  . VAL B 1 138 ? 104.862 104.051 132.746 1.00 233.63 ?  138  VAL B CB  1 
ATOM   3764 C CG1 . VAL B 1 138 ? 104.437 102.591 132.766 1.00 233.63 ?  138  VAL B CG1 1 
ATOM   3765 C CG2 . VAL B 1 138 ? 103.635 104.933 132.592 1.00 233.63 ?  138  VAL B CG2 1 
ATOM   3766 N N   . SER B 1 139 ? 108.016 104.059 133.694 1.00 209.26 ?  139  SER B N   1 
ATOM   3767 C CA  . SER B 1 139 ? 109.272 103.342 133.867 1.00 209.26 ?  139  SER B CA  1 
ATOM   3768 C C   . SER B 1 139 ? 109.723 103.365 135.314 1.00 209.26 ?  139  SER B C   1 
ATOM   3769 O O   . SER B 1 139 ? 110.297 102.402 135.800 1.00 209.26 ?  139  SER B O   1 
ATOM   3770 C CB  . SER B 1 139 ? 110.346 103.924 132.960 1.00 209.26 ?  139  SER B CB  1 
ATOM   3771 O OG  . SER B 1 139 ? 111.015 105.005 133.580 1.00 209.26 ?  139  SER B OG  1 
ATOM   3772 N N   . ALA B 1 140 ? 109.448 104.452 136.019 1.00 212.88 ?  140  ALA B N   1 
ATOM   3773 C CA  . ALA B 1 140 ? 109.796 104.532 137.425 1.00 212.88 ?  140  ALA B CA  1 
ATOM   3774 C C   . ALA B 1 140 ? 108.850 103.698 138.253 1.00 212.88 ?  140  ALA B C   1 
ATOM   3775 O O   . ALA B 1 140 ? 109.255 103.121 139.245 1.00 212.88 ?  140  ALA B O   1 
ATOM   3776 C CB  . ALA B 1 140 ? 109.766 105.964 137.897 1.00 212.88 ?  140  ALA B CB  1 
ATOM   3777 N N   . LYS B 1 141 ? 107.594 103.615 137.830 1.00 223.66 ?  141  LYS B N   1 
ATOM   3778 C CA  . LYS B 1 141 ? 106.600 102.817 138.544 1.00 223.66 ?  141  LYS B CA  1 
ATOM   3779 C C   . LYS B 1 141 ? 106.928 101.356 138.345 1.00 223.66 ?  141  LYS B C   1 
ATOM   3780 O O   . LYS B 1 141 ? 106.656 100.539 139.215 1.00 223.66 ?  141  LYS B O   1 
ATOM   3781 C CB  . LYS B 1 141 ? 105.191 103.100 138.022 1.00 223.66 ?  141  LYS B CB  1 
ATOM   3782 C CG  . LYS B 1 141 ? 104.569 104.417 138.466 1.00 223.66 ?  141  LYS B CG  1 
ATOM   3783 C CD  . LYS B 1 141 ? 105.222 104.979 139.715 1.00 223.66 ?  141  LYS B CD  1 
ATOM   3784 C CE  . LYS B 1 141 ? 104.233 105.758 140.562 1.00 223.66 ?  141  LYS B CE  1 
ATOM   3785 N NZ  . LYS B 1 141 ? 102.832 105.507 140.126 1.00 223.66 ?  141  LYS B NZ  1 
ATOM   3786 N N   . SER B 1 142 ? 107.505 101.020 137.197 1.00 217.81 ?  142  SER B N   1 
ATOM   3787 C CA  . SER B 1 142 ? 107.902 99.652  136.923 1.00 217.81 ?  142  SER B CA  1 
ATOM   3788 C C   . SER B 1 142 ? 109.144 99.299  137.714 1.00 217.81 ?  142  SER B C   1 
ATOM   3789 O O   . SER B 1 142 ? 109.291 98.178  138.169 1.00 217.81 ?  142  SER B O   1 
ATOM   3790 C CB  . SER B 1 142 ? 108.168 99.480  135.436 1.00 217.81 ?  142  SER B CB  1 
ATOM   3791 O OG  . SER B 1 142 ? 108.895 98.301  135.200 1.00 217.81 ?  142  SER B OG  1 
ATOM   3792 N N   . LEU B 1 143 ? 110.035 100.263 137.901 1.00 215.31 ?  143  LEU B N   1 
ATOM   3793 C CA  . LEU B 1 143 ? 111.230 100.028 138.688 1.00 215.31 ?  143  LEU B CA  1 
ATOM   3794 C C   . LEU B 1 143 ? 110.858 99.908  140.144 1.00 215.31 ?  143  LEU B C   1 
ATOM   3795 O O   . LEU B 1 143 ? 111.482 99.166  140.889 1.00 215.31 ?  143  LEU B O   1 
ATOM   3796 C CB  . LEU B 1 143 ? 112.205 101.181 138.508 1.00 215.31 ?  143  LEU B CB  1 
ATOM   3797 C CG  . LEU B 1 143 ? 113.572 100.862 137.915 1.00 215.31 ?  143  LEU B CG  1 
ATOM   3798 C CD1 . LEU B 1 143 ? 113.615 99.441  137.383 1.00 215.31 ?  143  LEU B CD1 1 
ATOM   3799 C CD2 . LEU B 1 143 ? 113.917 101.863 136.830 1.00 215.31 ?  143  LEU B CD2 1 
ATOM   3800 N N   . GLN B 1 144 ? 109.834 100.638 140.559 1.00 242.10 ?  144  GLN B N   1 
ATOM   3801 C CA  . GLN B 1 144 ? 109.375 100.549 141.930 1.00 242.10 ?  144  GLN B CA  1 
ATOM   3802 C C   . GLN B 1 144 ? 108.771 99.190  142.171 1.00 242.10 ?  144  GLN B C   1 
ATOM   3803 O O   . GLN B 1 144 ? 109.007 98.590  143.209 1.00 242.10 ?  144  GLN B O   1 
ATOM   3804 C CB  . GLN B 1 144 ? 108.346 101.634 142.224 1.00 242.10 ?  144  GLN B CB  1 
ATOM   3805 C CG  . GLN B 1 144 ? 108.955 102.954 142.656 1.00 242.10 ?  144  GLN B CG  1 
ATOM   3806 C CD  . GLN B 1 144 ? 108.078 104.131 142.294 1.00 242.10 ?  144  GLN B CD  1 
ATOM   3807 O OE1 . GLN B 1 144 ? 108.535 105.102 141.690 1.00 242.10 ?  144  GLN B OE1 1 
ATOM   3808 N NE2 . GLN B 1 144 ? 106.806 104.050 142.662 1.00 242.10 ?  144  GLN B NE2 1 
ATOM   3809 N N   . ALA B 1 145 ? 108.000 98.692  141.213 1.00 229.27 ?  145  ALA B N   1 
ATOM   3810 C CA  . ALA B 1 145 ? 107.410 97.370  141.337 1.00 229.27 ?  145  ALA B CA  1 
ATOM   3811 C C   . ALA B 1 145 ? 108.487 96.317  141.350 1.00 229.27 ?  145  ALA B C   1 
ATOM   3812 O O   . ALA B 1 145 ? 108.385 95.360  142.089 1.00 229.27 ?  145  ALA B O   1 
ATOM   3813 C CB  . ALA B 1 145 ? 106.441 97.116  140.204 1.00 229.27 ?  145  ALA B CB  1 
ATOM   3814 N N   . TYR B 1 146 ? 109.518 96.485  140.533 1.00 220.90 ?  146  TYR B N   1 
ATOM   3815 C CA  . TYR B 1 146 ? 110.638 95.553  140.508 1.00 220.90 ?  146  TYR B CA  1 
ATOM   3816 C C   . TYR B 1 146 ? 111.233 95.444  141.896 1.00 220.90 ?  146  TYR B C   1 
ATOM   3817 O O   . TYR B 1 146 ? 111.359 94.351  142.434 1.00 220.90 ?  146  TYR B O   1 
ATOM   3818 C CB  . TYR B 1 146 ? 111.666 96.096  139.523 1.00 220.90 ?  146  TYR B CB  1 
ATOM   3819 C CG  . TYR B 1 146 ? 112.865 95.248  139.202 1.00 220.90 ?  146  TYR B CG  1 
ATOM   3820 C CD1 . TYR B 1 146 ? 112.859 93.872  139.371 1.00 220.90 ?  146  TYR B CD1 1 
ATOM   3821 C CD2 . TYR B 1 146 ? 114.009 95.839  138.695 1.00 220.90 ?  146  TYR B CD2 1 
ATOM   3822 C CE1 . TYR B 1 146 ? 113.969 93.116  139.058 1.00 220.90 ?  146  TYR B CE1 1 
ATOM   3823 C CE2 . TYR B 1 146 ? 115.118 95.094  138.381 1.00 220.90 ?  146  TYR B CE2 1 
ATOM   3824 C CZ  . TYR B 1 146 ? 115.093 93.737  138.563 1.00 220.90 ?  146  TYR B CZ  1 
ATOM   3825 O OH  . TYR B 1 146 ? 116.209 93.017  138.235 1.00 220.90 ?  146  TYR B OH  1 
ATOM   3826 N N   . LYS B 1 147 ? 111.584 96.576  142.487 1.00 198.72 ?  147  LYS B N   1 
ATOM   3827 C CA  . LYS B 1 147 ? 112.185 96.570  143.810 1.00 198.72 ?  147  LYS B CA  1 
ATOM   3828 C C   . LYS B 1 147 ? 111.245 96.021  144.861 1.00 198.72 ?  147  LYS B C   1 
ATOM   3829 O O   . LYS B 1 147 ? 111.666 95.278  145.738 1.00 198.72 ?  147  LYS B O   1 
ATOM   3830 C CB  . LYS B 1 147 ? 112.628 97.978  144.195 1.00 198.72 ?  147  LYS B CB  1 
ATOM   3831 C CG  . LYS B 1 147 ? 114.049 98.307  143.782 1.00 198.72 ?  147  LYS B CG  1 
ATOM   3832 C CD  . LYS B 1 147 ? 114.121 99.665  143.108 1.00 198.72 ?  147  LYS B CD  1 
ATOM   3833 C CE  . LYS B 1 147 ? 115.129 99.646  141.975 1.00 198.72 ?  147  LYS B CE  1 
ATOM   3834 N NZ  . LYS B 1 147 ? 116.409 99.027  142.419 1.00 198.72 ?  147  LYS B NZ  1 
ATOM   3835 N N   . TRP B 1 148 ? 109.971 96.380  144.778 1.00 237.89 ?  148  TRP B N   1 
ATOM   3836 C CA  . TRP B 1 148 ? 108.993 95.888  145.733 1.00 237.89 ?  148  TRP B CA  1 
ATOM   3837 C C   . TRP B 1 148 ? 108.852 94.384  145.637 1.00 237.89 ?  148  TRP B C   1 
ATOM   3838 O O   . TRP B 1 148 ? 108.875 93.710  146.645 1.00 237.89 ?  148  TRP B O   1 
ATOM   3839 C CB  . TRP B 1 148 ? 107.634 96.557  145.528 1.00 237.89 ?  148  TRP B CB  1 
ATOM   3840 C CG  . TRP B 1 148 ? 106.507 95.810  146.165 1.00 237.89 ?  148  TRP B CG  1 
ATOM   3841 C CD1 . TRP B 1 148 ? 106.230 95.724  147.499 1.00 237.89 ?  148  TRP B CD1 1 
ATOM   3842 C CD2 . TRP B 1 148 ? 105.513 95.027  145.498 1.00 237.89 ?  148  TRP B CD2 1 
ATOM   3843 N NE1 . TRP B 1 148 ? 105.125 94.938  147.701 1.00 237.89 ?  148  TRP B NE1 1 
ATOM   3844 C CE2 . TRP B 1 148 ? 104.666 94.497  146.489 1.00 237.89 ?  148  TRP B CE2 1 
ATOM   3845 C CE3 . TRP B 1 148 ? 105.257 94.724  144.159 1.00 237.89 ?  148  TRP B CE3 1 
ATOM   3846 C CZ2 . TRP B 1 148 ? 103.580 93.685  146.182 1.00 237.89 ?  148  TRP B CZ2 1 
ATOM   3847 C CZ3 . TRP B 1 148 ? 104.184 93.915  143.857 1.00 237.89 ?  148  TRP B CZ3 1 
ATOM   3848 C CH2 . TRP B 1 148 ? 103.355 93.408  144.863 1.00 237.89 ?  148  TRP B CH2 1 
ATOM   3849 N N   . SER B 1 149 ? 108.711 93.854  144.429 1.00 206.54 ?  149  SER B N   1 
ATOM   3850 C CA  . SER B 1 149 ? 108.550 92.422  144.244 1.00 206.54 ?  149  SER B CA  1 
ATOM   3851 C C   . SER B 1 149 ? 109.762 91.686  144.749 1.00 206.54 ?  149  SER B C   1 
ATOM   3852 O O   . SER B 1 149 ? 109.646 90.623  145.343 1.00 206.54 ?  149  SER B O   1 
ATOM   3853 C CB  . SER B 1 149 ? 108.343 92.089  142.771 1.00 206.54 ?  149  SER B CB  1 
ATOM   3854 O OG  . SER B 1 149 ? 107.210 92.750  142.243 1.00 206.54 ?  149  SER B OG  1 
ATOM   3855 N N   . TYR B 1 150 ? 110.936 92.253  144.518 1.00 168.90 ?  150  TYR B N   1 
ATOM   3856 C CA  . TYR B 1 150 ? 112.162 91.628  144.961 1.00 168.90 ?  150  TYR B CA  1 
ATOM   3857 C C   . TYR B 1 150 ? 112.228 91.590  146.478 1.00 168.90 ?  150  TYR B C   1 
ATOM   3858 O O   . TYR B 1 150 ? 112.717 90.625  147.056 1.00 168.90 ?  150  TYR B O   1 
ATOM   3859 C CB  . TYR B 1 150 ? 113.345 92.392  144.384 1.00 168.90 ?  150  TYR B CB  1 
ATOM   3860 C CG  . TYR B 1 150 ? 114.674 91.828  144.767 1.00 168.90 ?  150  TYR B CG  1 
ATOM   3861 C CD1 . TYR B 1 150 ? 115.096 90.610  144.266 1.00 168.90 ?  150  TYR B CD1 1 
ATOM   3862 C CD2 . TYR B 1 150 ? 115.509 92.510  145.637 1.00 168.90 ?  150  TYR B CD2 1 
ATOM   3863 C CE1 . TYR B 1 150 ? 116.320 90.092  144.613 1.00 168.90 ?  150  TYR B CE1 1 
ATOM   3864 C CE2 . TYR B 1 150 ? 116.727 91.993  145.996 1.00 168.90 ?  150  TYR B CE2 1 
ATOM   3865 C CZ  . TYR B 1 150 ? 117.122 90.785  145.479 1.00 168.90 ?  150  TYR B CZ  1 
ATOM   3866 O OH  . TYR B 1 150 ? 118.327 90.270  145.838 1.00 168.90 ?  150  TYR B OH  1 
ATOM   3867 N N   . ALA B 1 151 ? 111.737 92.637  147.128 1.00 187.55 ?  151  ALA B N   1 
ATOM   3868 C CA  . ALA B 1 151 ? 111.759 92.695  148.581 1.00 187.55 ?  151  ALA B CA  1 
ATOM   3869 C C   . ALA B 1 151 ? 110.619 91.889  149.167 1.00 187.55 ?  151  ALA B C   1 
ATOM   3870 O O   . ALA B 1 151 ? 110.724 91.391  150.285 1.00 187.55 ?  151  ALA B O   1 
ATOM   3871 C CB  . ALA B 1 151 ? 111.676 94.134  149.046 1.00 187.55 ?  151  ALA B CB  1 
ATOM   3872 N N   . GLN B 1 152 ? 109.588 91.624  148.379 1.00 228.04 ?  152  GLN B N   1 
ATOM   3873 C CA  . GLN B 1 152 ? 108.510 90.764  148.852 1.00 228.04 ?  152  GLN B CA  1 
ATOM   3874 C C   . GLN B 1 152 ? 108.962 89.308  148.906 1.00 228.04 ?  152  GLN B C   1 
ATOM   3875 O O   . GLN B 1 152 ? 108.323 88.482  149.553 1.00 228.04 ?  152  GLN B O   1 
ATOM   3876 C CB  . GLN B 1 152 ? 107.276 90.913  147.963 1.00 228.04 ?  152  GLN B CB  1 
ATOM   3877 C CG  . GLN B 1 152 ? 106.090 91.593  148.631 1.00 228.04 ?  152  GLN B CG  1 
ATOM   3878 C CD  . GLN B 1 152 ? 106.486 92.507  149.778 1.00 228.04 ?  152  GLN B CD  1 
ATOM   3879 O OE1 . GLN B 1 152 ? 107.118 93.544  149.576 1.00 228.04 ?  152  GLN B OE1 1 
ATOM   3880 N NE2 . GLN B 1 152 ? 106.098 92.132  150.991 1.00 228.04 ?  152  GLN B NE2 1 
ATOM   3881 N N   . MET B 1 153 ? 110.066 88.991  148.238 1.00 256.85 ?  153  MET B N   1 
ATOM   3882 C CA  . MET B 1 153 ? 110.579 87.620  148.232 1.00 256.85 ?  153  MET B CA  1 
ATOM   3883 C C   . MET B 1 153 ? 111.769 87.489  149.159 1.00 256.85 ?  153  MET B C   1 
ATOM   3884 O O   . MET B 1 153 ? 112.478 86.490  149.101 1.00 256.85 ?  153  MET B O   1 
ATOM   3885 C CB  . MET B 1 153 ? 110.994 87.208  146.821 1.00 256.85 ?  153  MET B CB  1 
ATOM   3886 C CG  . MET B 1 153 ? 109.921 87.388  145.766 1.00 256.85 ?  153  MET B CG  1 
ATOM   3887 S SD  . MET B 1 153 ? 108.458 86.385  146.070 1.00 256.85 ?  153  MET B SD  1 
ATOM   3888 C CE  . MET B 1 153 ? 108.181 85.699  144.440 1.00 256.85 ?  153  MET B CE  1 
ATOM   3889 N N   . GLN B 1 154 ? 111.976 88.469  150.031 1.00 267.26 ?  154  GLN B N   1 
ATOM   3890 C CA  . GLN B 1 154 ? 113.148 88.486  150.919 1.00 267.26 ?  154  GLN B CA  1 
ATOM   3891 C C   . GLN B 1 154 ? 113.774 87.174  151.409 1.00 267.26 ?  154  GLN B C   1 
ATOM   3892 O O   . GLN B 1 154 ? 114.932 86.902  151.095 1.00 267.26 ?  154  GLN B O   1 
ATOM   3893 C CB  . GLN B 1 154 ? 112.930 89.460  152.087 1.00 267.26 ?  154  GLN B CB  1 
ATOM   3894 C CG  . GLN B 1 154 ? 114.208 90.094  152.612 1.00 267.26 ?  154  GLN B CG  1 
ATOM   3895 C CD  . GLN B 1 154 ? 115.015 90.771  151.523 1.00 267.26 ?  154  GLN B CD  1 
ATOM   3896 O OE1 . GLN B 1 154 ? 114.534 91.687  150.855 1.00 267.26 ?  154  GLN B OE1 1 
ATOM   3897 N NE2 . GLN B 1 154 ? 116.253 90.325  151.339 1.00 267.26 ?  154  GLN B NE2 1 
ATOM   3898 N N   . PRO B 1 155 ? 113.035 86.359  152.183 1.00 242.74 ?  155  PRO B N   1 
ATOM   3899 C CA  . PRO B 1 155 ? 113.716 85.165  152.706 1.00 242.74 ?  155  PRO B CA  1 
ATOM   3900 C C   . PRO B 1 155 ? 114.222 84.206  151.637 1.00 242.74 ?  155  PRO B C   1 
ATOM   3901 O O   . PRO B 1 155 ? 115.403 83.862  151.655 1.00 242.74 ?  155  PRO B O   1 
ATOM   3902 C CB  . PRO B 1 155 ? 112.631 84.476  153.545 1.00 242.74 ?  155  PRO B CB  1 
ATOM   3903 C CG  . PRO B 1 155 ? 111.592 85.519  153.788 1.00 242.74 ?  155  PRO B CG  1 
ATOM   3904 C CD  . PRO B 1 155 ? 111.612 86.378  152.564 1.00 242.74 ?  155  PRO B CD  1 
ATOM   3905 N N   . SER B 1 156 ? 113.360 83.778  150.723 1.00 232.47 ?  156  SER B N   1 
ATOM   3906 C CA  . SER B 1 156 ? 113.759 82.788  149.728 1.00 232.47 ?  156  SER B CA  1 
ATOM   3907 C C   . SER B 1 156 ? 114.676 83.328  148.653 1.00 232.47 ?  156  SER B C   1 
ATOM   3908 O O   . SER B 1 156 ? 114.288 84.200  147.889 1.00 232.47 ?  156  SER B O   1 
ATOM   3909 C CB  . SER B 1 156 ? 112.526 82.164  149.083 1.00 232.47 ?  156  SER B CB  1 
ATOM   3910 O OG  . SER B 1 156 ? 112.889 81.122  148.198 1.00 232.47 ?  156  SER B OG  1 
ATOM   3911 N N   . LEU B 1 157 ? 115.887 82.792  148.577 1.00 209.06 ?  157  LEU B N   1 
ATOM   3912 C CA  . LEU B 1 157 ? 116.836 83.218  147.551 1.00 209.06 ?  157  LEU B CA  1 
ATOM   3913 C C   . LEU B 1 157 ? 116.474 82.798  146.119 1.00 209.06 ?  157  LEU B C   1 
ATOM   3914 O O   . LEU B 1 157 ? 116.627 83.595  145.200 1.00 209.06 ?  157  LEU B O   1 
ATOM   3915 C CB  . LEU B 1 157 ? 118.260 82.776  147.909 1.00 209.06 ?  157  LEU B CB  1 
ATOM   3916 C CG  . LEU B 1 157 ? 119.261 83.882  148.242 1.00 209.06 ?  157  LEU B CG  1 
ATOM   3917 C CD1 . LEU B 1 157 ? 120.415 83.872  147.253 1.00 209.06 ?  157  LEU B CD1 1 
ATOM   3918 C CD2 . LEU B 1 157 ? 118.578 85.240  148.261 1.00 209.06 ?  157  LEU B CD2 1 
ATOM   3919 N N   . PRO B 1 158 ? 116.015 81.547  145.909 1.00 201.91 ?  158  PRO B N   1 
ATOM   3920 C CA  . PRO B 1 158 ? 115.605 81.230  144.533 1.00 201.91 ?  158  PRO B CA  1 
ATOM   3921 C C   . PRO B 1 158 ? 114.457 82.107  144.051 1.00 201.91 ?  158  PRO B C   1 
ATOM   3922 O O   . PRO B 1 158 ? 114.419 82.449  142.875 1.00 201.91 ?  158  PRO B O   1 
ATOM   3923 C CB  . PRO B 1 158 ? 115.154 79.765  144.623 1.00 201.91 ?  158  PRO B CB  1 
ATOM   3924 C CG  . PRO B 1 158 ? 115.064 79.446  146.077 1.00 201.91 ?  158  PRO B CG  1 
ATOM   3925 C CD  . PRO B 1 158 ? 116.069 80.331  146.737 1.00 201.91 ?  158  PRO B CD  1 
ATOM   3926 N N   . LEU B 1 159 ? 113.534 82.457  144.935 1.00 219.69 ?  159  LEU B N   1 
ATOM   3927 C CA  . LEU B 1 159 ? 112.425 83.325  144.582 1.00 219.69 ?  159  LEU B CA  1 
ATOM   3928 C C   . LEU B 1 159 ? 112.923 84.722  144.295 1.00 219.69 ?  159  LEU B C   1 
ATOM   3929 O O   . LEU B 1 159 ? 112.420 85.391  143.397 1.00 219.69 ?  159  LEU B O   1 
ATOM   3930 C CB  . LEU B 1 159 ? 111.403 83.353  145.705 1.00 219.69 ?  159  LEU B CB  1 
ATOM   3931 C CG  . LEU B 1 159 ? 110.446 82.167  145.710 1.00 219.69 ?  159  LEU B CG  1 
ATOM   3932 C CD1 . LEU B 1 159 ? 109.328 82.393  146.713 1.00 219.69 ?  159  LEU B CD1 1 
ATOM   3933 C CD2 . LEU B 1 159 ? 109.889 81.939  144.315 1.00 219.69 ?  159  LEU B CD2 1 
ATOM   3934 N N   . GLN B 1 160 ? 113.914 85.172  145.053 1.00 190.31 ?  160  GLN B N   1 
ATOM   3935 C CA  . GLN B 1 160 ? 114.496 86.477  144.803 1.00 190.31 ?  160  GLN B CA  1 
ATOM   3936 C C   . GLN B 1 160 ? 115.128 86.470  143.431 1.00 190.31 ?  160  GLN B C   1 
ATOM   3937 O O   . GLN B 1 160 ? 114.950 87.408  142.667 1.00 190.31 ?  160  GLN B O   1 
ATOM   3938 C CB  . GLN B 1 160 ? 115.537 86.802  145.865 1.00 190.31 ?  160  GLN B CB  1 
ATOM   3939 C CG  . GLN B 1 160 ? 114.937 87.238  147.188 1.00 190.31 ?  160  GLN B CG  1 
ATOM   3940 C CD  . GLN B 1 160 ? 115.742 88.323  147.865 1.00 190.31 ?  160  GLN B CD  1 
ATOM   3941 O OE1 . GLN B 1 160 ? 116.969 88.273  147.895 1.00 190.31 ?  160  GLN B OE1 1 
ATOM   3942 N NE2 . GLN B 1 160 ? 115.053 89.316  148.412 1.00 190.31 ?  160  GLN B NE2 1 
ATOM   3943 N N   . PHE B 1 161 ? 115.847 85.401  143.106 1.00 210.02 ?  161  PHE B N   1 
ATOM   3944 C CA  . PHE B 1 161 ? 116.471 85.281  141.797 1.00 210.02 ?  161  PHE B CA  1 
ATOM   3945 C C   . PHE B 1 161 ? 115.434 85.331  140.713 1.00 210.02 ?  161  PHE B C   1 
ATOM   3946 O O   . PHE B 1 161 ? 115.617 86.027  139.728 1.00 210.02 ?  161  PHE B O   1 
ATOM   3947 C CB  . PHE B 1 161 ? 117.263 83.983  141.690 1.00 210.02 ?  161  PHE B CB  1 
ATOM   3948 C CG  . PHE B 1 161 ? 118.112 83.890  140.459 1.00 210.02 ?  161  PHE B CG  1 
ATOM   3949 C CD1 . PHE B 1 161 ? 119.251 84.660  140.335 1.00 210.02 ?  161  PHE B CD1 1 
ATOM   3950 C CD2 . PHE B 1 161 ? 117.770 83.035  139.426 1.00 210.02 ?  161  PHE B CD2 1 
ATOM   3951 C CE1 . PHE B 1 161 ? 120.040 84.579  139.208 1.00 210.02 ?  161  PHE B CE1 1 
ATOM   3952 C CE2 . PHE B 1 161 ? 118.552 82.950  138.293 1.00 210.02 ?  161  PHE B CE2 1 
ATOM   3953 C CZ  . PHE B 1 161 ? 119.691 83.722  138.184 1.00 210.02 ?  161  PHE B CZ  1 
ATOM   3954 N N   . LEU B 1 162 ? 114.348 84.592  140.895 1.00 201.58 ?  162  LEU B N   1 
ATOM   3955 C CA  . LEU B 1 162 ? 113.283 84.578  139.911 1.00 201.58 ?  162  LEU B CA  1 
ATOM   3956 C C   . LEU B 1 162 ? 112.824 85.985  139.581 1.00 201.58 ?  162  LEU B C   1 
ATOM   3957 O O   . LEU B 1 162 ? 112.894 86.391  138.442 1.00 201.58 ?  162  LEU B O   1 
ATOM   3958 C CB  . LEU B 1 162 ? 112.109 83.745  140.402 1.00 201.58 ?  162  LEU B CB  1 
ATOM   3959 C CG  . LEU B 1 162 ? 111.844 82.454  139.633 1.00 201.58 ?  162  LEU B CG  1 
ATOM   3960 C CD1 . LEU B 1 162 ? 112.862 82.278  138.518 1.00 201.58 ?  162  LEU B CD1 1 
ATOM   3961 C CD2 . LEU B 1 162 ? 111.867 81.264  140.578 1.00 201.58 ?  162  LEU B CD2 1 
ATOM   3962 N N   . VAL B 1 163 ? 112.381 86.738  140.578 1.00 217.21 ?  163  VAL B N   1 
ATOM   3963 C CA  . VAL B 1 163 ? 111.964 88.114  140.339 1.00 217.21 ?  163  VAL B CA  1 
ATOM   3964 C C   . VAL B 1 163 ? 113.068 88.923  139.682 1.00 217.21 ?  163  VAL B C   1 
ATOM   3965 O O   . VAL B 1 163 ? 112.849 89.555  138.649 1.00 217.21 ?  163  VAL B O   1 
ATOM   3966 C CB  . VAL B 1 163 ? 111.503 88.802  141.635 1.00 217.21 ?  163  VAL B CB  1 
ATOM   3967 C CG1 . VAL B 1 163 ? 111.420 90.309  141.447 1.00 217.21 ?  163  VAL B CG1 1 
ATOM   3968 C CG2 . VAL B 1 163 ? 110.142 88.265  142.038 1.00 217.21 ?  163  VAL B CG2 1 
ATOM   3969 N N   . TRP B 1 164 ? 114.271 88.868  140.241 1.00 191.84 ?  164  TRP B N   1 
ATOM   3970 C CA  . TRP B 1 164 ? 115.365 89.664  139.708 1.00 191.84 ?  164  TRP B CA  1 
ATOM   3971 C C   . TRP B 1 164 ? 115.688 89.397  138.238 1.00 191.84 ?  164  TRP B C   1 
ATOM   3972 O O   . TRP B 1 164 ? 116.144 90.288  137.541 1.00 191.84 ?  164  TRP B O   1 
ATOM   3973 C CB  . TRP B 1 164 ? 116.622 89.529  140.568 1.00 191.84 ?  164  TRP B CB  1 
ATOM   3974 C CG  . TRP B 1 164 ? 117.579 90.648  140.352 1.00 191.84 ?  164  TRP B CG  1 
ATOM   3975 C CD1 . TRP B 1 164 ? 118.679 90.632  139.559 1.00 191.84 ?  164  TRP B CD1 1 
ATOM   3976 C CD2 . TRP B 1 164 ? 117.504 91.964  140.907 1.00 191.84 ?  164  TRP B CD2 1 
ATOM   3977 N NE1 . TRP B 1 164 ? 119.303 91.850  139.585 1.00 191.84 ?  164  TRP B NE1 1 
ATOM   3978 C CE2 . TRP B 1 164 ? 118.601 92.688  140.408 1.00 191.84 ?  164  TRP B CE2 1 
ATOM   3979 C CE3 . TRP B 1 164 ? 116.615 92.603  141.772 1.00 191.84 ?  164  TRP B CE3 1 
ATOM   3980 C CZ2 . TRP B 1 164 ? 118.836 94.011  140.752 1.00 191.84 ?  164  TRP B CZ2 1 
ATOM   3981 C CZ3 . TRP B 1 164 ? 116.850 93.914  142.112 1.00 191.84 ?  164  TRP B CZ3 1 
ATOM   3982 C CH2 . TRP B 1 164 ? 117.952 94.606  141.604 1.00 191.84 ?  164  TRP B CH2 1 
ATOM   3983 N N   . VAL B 1 165 ? 115.465 88.185  137.755 1.00 211.85 ?  165  VAL B N   1 
ATOM   3984 C CA  . VAL B 1 165 ? 115.722 87.931  136.354 1.00 211.85 ?  165  VAL B CA  1 
ATOM   3985 C C   . VAL B 1 165 ? 114.488 87.993  135.468 1.00 211.85 ?  165  VAL B C   1 
ATOM   3986 O O   . VAL B 1 165 ? 114.591 88.434  134.337 1.00 211.85 ?  165  VAL B O   1 
ATOM   3987 C CB  . VAL B 1 165 ? 116.535 86.637  136.113 1.00 211.85 ?  165  VAL B CB  1 
ATOM   3988 C CG1 . VAL B 1 165 ? 117.840 86.685  136.885 1.00 211.85 ?  165  VAL B CG1 1 
ATOM   3989 C CG2 . VAL B 1 165 ? 115.741 85.387  136.460 1.00 211.85 ?  165  VAL B CG2 1 
ATOM   3990 N N   . THR B 1 166 ? 113.322 87.605  135.970 1.00 246.51 ?  166  THR B N   1 
ATOM   3991 C CA  . THR B 1 166 ? 112.136 87.558  135.119 1.00 246.51 ?  166  THR B CA  1 
ATOM   3992 C C   . THR B 1 166 ? 111.510 88.905  134.881 1.00 246.51 ?  166  THR B C   1 
ATOM   3993 O O   . THR B 1 166 ? 111.045 89.161  133.793 1.00 246.51 ?  166  THR B O   1 
ATOM   3994 C CB  . THR B 1 166 ? 111.045 86.600  135.638 1.00 246.51 ?  166  THR B CB  1 
ATOM   3995 O OG1 . THR B 1 166 ? 110.650 86.982  136.960 1.00 246.51 ?  166  THR B OG1 1 
ATOM   3996 C CG2 . THR B 1 166 ? 111.546 85.163  135.633 1.00 246.51 ?  166  THR B CG2 1 
ATOM   3997 N N   . PHE B 1 167 ? 111.473 89.762  135.888 1.00 237.22 ?  167  PHE B N   1 
ATOM   3998 C CA  . PHE B 1 167 ? 110.962 91.111  135.675 1.00 237.22 ?  167  PHE B CA  1 
ATOM   3999 C C   . PHE B 1 167 ? 111.659 91.781  134.482 1.00 237.22 ?  167  PHE B C   1 
ATOM   4000 O O   . PHE B 1 167 ? 110.982 92.199  133.540 1.00 237.22 ?  167  PHE B O   1 
ATOM   4001 C CB  . PHE B 1 167 ? 111.022 91.929  136.970 1.00 237.22 ?  167  PHE B CB  1 
ATOM   4002 C CG  . PHE B 1 167 ? 110.032 93.050  137.043 1.00 237.22 ?  167  PHE B CG  1 
ATOM   4003 C CD1 . PHE B 1 167 ? 110.248 94.234  136.361 1.00 237.22 ?  167  PHE B CD1 1 
ATOM   4004 C CD2 . PHE B 1 167 ? 108.901 92.933  137.830 1.00 237.22 ?  167  PHE B CD2 1 
ATOM   4005 C CE1 . PHE B 1 167 ? 109.341 95.266  136.440 1.00 237.22 ?  167  PHE B CE1 1 
ATOM   4006 C CE2 . PHE B 1 167 ? 107.991 93.964  137.914 1.00 237.22 ?  167  PHE B CE2 1 
ATOM   4007 C CZ  . PHE B 1 167 ? 108.209 95.133  137.216 1.00 237.22 ?  167  PHE B CZ  1 
ATOM   4008 N N   . PRO B 1 168 ? 113.011 91.867  134.484 1.00 249.60 ?  168  PRO B N   1 
ATOM   4009 C CA  . PRO B 1 168 ? 113.610 92.440  133.276 1.00 249.60 ?  168  PRO B CA  1 
ATOM   4010 C C   . PRO B 1 168 ? 113.366 91.601  132.031 1.00 249.60 ?  168  PRO B C   1 
ATOM   4011 O O   . PRO B 1 168 ? 113.121 92.174  130.985 1.00 249.60 ?  168  PRO B O   1 
ATOM   4012 C CB  . PRO B 1 168 ? 115.096 92.440  133.599 1.00 249.60 ?  168  PRO B CB  1 
ATOM   4013 C CG  . PRO B 1 168 ? 115.160 92.536  135.062 1.00 249.60 ?  168  PRO B CG  1 
ATOM   4014 C CD  . PRO B 1 168 ? 114.039 91.669  135.520 1.00 249.60 ?  168  PRO B CD  1 
ATOM   4015 N N   . LEU B 1 169 ? 113.441 90.278  132.134 1.00 300.80 ?  169  LEU B N   1 
ATOM   4016 C CA  . LEU B 1 169 ? 113.258 89.416  130.979 1.00 300.80 ?  169  LEU B CA  1 
ATOM   4017 C C   . LEU B 1 169 ? 111.934 89.675  130.309 1.00 300.80 ?  169  LEU B C   1 
ATOM   4018 O O   . LEU B 1 169 ? 111.892 89.886  129.113 1.00 300.80 ?  169  LEU B O   1 
ATOM   4019 C CB  . LEU B 1 169 ? 113.348 87.946  131.368 1.00 300.80 ?  169  LEU B CB  1 
ATOM   4020 C CG  . LEU B 1 169 ? 114.635 87.216  131.002 1.00 300.80 ?  169  LEU B CG  1 
ATOM   4021 C CD1 . LEU B 1 169 ? 114.846 86.020  131.915 1.00 300.80 ?  169  LEU B CD1 1 
ATOM   4022 C CD2 . LEU B 1 169 ? 114.538 86.762  129.563 1.00 300.80 ?  169  LEU B CD2 1 
ATOM   4023 N N   . VAL B 1 170 ? 110.855 89.673  131.077 1.00 303.99 ?  170  VAL B N   1 
ATOM   4024 C CA  . VAL B 1 170 ? 109.533 89.910  130.524 1.00 303.99 ?  170  VAL B CA  1 
ATOM   4025 C C   . VAL B 1 170 ? 109.498 91.258  129.838 1.00 303.99 ?  170  VAL B C   1 
ATOM   4026 O O   . VAL B 1 170 ? 109.063 91.359  128.702 1.00 303.99 ?  170  VAL B O   1 
ATOM   4027 C CB  . VAL B 1 170 ? 108.444 89.821  131.615 1.00 303.99 ?  170  VAL B CB  1 
ATOM   4028 C CG1 . VAL B 1 170 ? 107.124 90.414  131.146 1.00 303.99 ?  170  VAL B CG1 1 
ATOM   4029 C CG2 . VAL B 1 170 ? 108.247 88.374  132.037 1.00 303.99 ?  170  VAL B CG2 1 
ATOM   4030 N N   . LEU B 1 171 ? 110.001 92.289  130.500 1.00 296.97 ?  171  LEU B N   1 
ATOM   4031 C CA  . LEU B 1 171 ? 109.951 93.627  129.933 1.00 296.97 ?  171  LEU B CA  1 
ATOM   4032 C C   . LEU B 1 171 ? 110.772 93.796  128.663 1.00 296.97 ?  171  LEU B C   1 
ATOM   4033 O O   . LEU B 1 171 ? 110.336 94.456  127.734 1.00 296.97 ?  171  LEU B O   1 
ATOM   4034 C CB  . LEU B 1 171 ? 110.372 94.644  130.980 1.00 296.97 ?  171  LEU B CB  1 
ATOM   4035 C CG  . LEU B 1 171 ? 109.274 94.921  131.998 1.00 296.97 ?  171  LEU B CG  1 
ATOM   4036 C CD1 . LEU B 1 171 ? 109.613 96.179  132.762 1.00 296.97 ?  171  LEU B CD1 1 
ATOM   4037 C CD2 . LEU B 1 171 ? 107.931 95.066  131.302 1.00 296.97 ?  171  LEU B CD2 1 
ATOM   4038 N N   . ILE B 1 172 ? 111.948 93.190  128.612 1.00 290.81 ?  172  ILE B N   1 
ATOM   4039 C CA  . ILE B 1 172 ? 112.793 93.288  127.431 1.00 290.81 ?  172  ILE B CA  1 
ATOM   4040 C C   . ILE B 1 172 ? 112.240 92.418  126.313 1.00 290.81 ?  172  ILE B C   1 
ATOM   4041 O O   . ILE B 1 172 ? 112.250 92.805  125.150 1.00 290.81 ?  172  ILE B O   1 
ATOM   4042 C CB  . ILE B 1 172 ? 114.255 92.925  127.754 1.00 290.81 ?  172  ILE B CB  1 
ATOM   4043 C CG1 . ILE B 1 172 ? 114.850 93.949  128.718 1.00 290.81 ?  172  ILE B CG1 1 
ATOM   4044 C CG2 . ILE B 1 172 ? 115.103 92.875  126.497 1.00 290.81 ?  172  ILE B CG2 1 
ATOM   4045 C CD1 . ILE B 1 172 ? 115.018 95.324  128.117 1.00 290.81 ?  172  ILE B CD1 1 
ATOM   4046 N N   . LEU B 1 173 ? 111.715 91.254  126.661 1.00 334.45 ?  173  LEU B N   1 
ATOM   4047 C CA  . LEU B 1 173 ? 111.114 90.399  125.650 1.00 334.45 ?  173  LEU B CA  1 
ATOM   4048 C C   . LEU B 1 173 ? 109.908 91.098  125.080 1.00 334.45 ?  173  LEU B C   1 
ATOM   4049 O O   . LEU B 1 173 ? 109.680 91.040  123.882 1.00 334.45 ?  173  LEU B O   1 
ATOM   4050 C CB  . LEU B 1 173 ? 110.715 89.051  126.231 1.00 334.45 ?  173  LEU B CB  1 
ATOM   4051 C CG  . LEU B 1 173 ? 111.574 87.866  125.794 1.00 334.45 ?  173  LEU B CG  1 
ATOM   4052 C CD1 . LEU B 1 173 ? 112.943 88.331  125.336 1.00 334.45 ?  173  LEU B CD1 1 
ATOM   4053 C CD2 . LEU B 1 173 ? 111.692 86.854  126.918 1.00 334.45 ?  173  LEU B CD2 1 
ATOM   4054 N N   . PHE B 1 174 ? 109.138 91.771  125.925 1.00 322.85 ?  174  PHE B N   1 
ATOM   4055 C CA  . PHE B 1 174 ? 108.004 92.537  125.443 1.00 322.85 ?  174  PHE B CA  1 
ATOM   4056 C C   . PHE B 1 174 ? 108.493 93.632  124.516 1.00 322.85 ?  174  PHE B C   1 
ATOM   4057 O O   . PHE B 1 174 ? 107.955 93.797  123.445 1.00 322.85 ?  174  PHE B O   1 
ATOM   4058 C CB  . PHE B 1 174 ? 107.215 93.140  126.602 1.00 322.85 ?  174  PHE B CB  1 
ATOM   4059 C CG  . PHE B 1 174 ? 106.209 94.168  126.182 1.00 322.85 ?  174  PHE B CG  1 
ATOM   4060 C CD1 . PHE B 1 174 ? 105.058 93.794  125.511 1.00 322.85 ?  174  PHE B CD1 1 
ATOM   4061 C CD2 . PHE B 1 174 ? 106.414 95.509  126.456 1.00 322.85 ?  174  PHE B CD2 1 
ATOM   4062 C CE1 . PHE B 1 174 ? 104.132 94.737  125.119 1.00 322.85 ?  174  PHE B CE1 1 
ATOM   4063 C CE2 . PHE B 1 174 ? 105.496 96.456  126.062 1.00 322.85 ?  174  PHE B CE2 1 
ATOM   4064 C CZ  . PHE B 1 174 ? 104.351 96.069  125.395 1.00 322.85 ?  174  PHE B CZ  1 
ATOM   4065 N N   . SER B 1 175 ? 109.515 94.375  124.925 1.00 290.57 ?  175  SER B N   1 
ATOM   4066 C CA  . SER B 1 175 ? 110.065 95.430  124.085 1.00 290.57 ?  175  SER B CA  1 
ATOM   4067 C C   . SER B 1 175 ? 110.392 94.906  122.706 1.00 290.57 ?  175  SER B C   1 
ATOM   4068 O O   . SER B 1 175 ? 109.938 95.455  121.707 1.00 290.57 ?  175  SER B O   1 
ATOM   4069 C CB  . SER B 1 175 ? 111.326 96.021  124.708 1.00 290.57 ?  175  SER B CB  1 
ATOM   4070 O OG  . SER B 1 175 ? 111.079 96.551  125.991 1.00 290.57 ?  175  SER B OG  1 
ATOM   4071 N N   . ALA B 1 176 ? 111.169 93.833  122.644 1.00 295.67 ?  176  ALA B N   1 
ATOM   4072 C CA  . ALA B 1 176 ? 111.559 93.263  121.368 1.00 295.67 ?  176  ALA B CA  1 
ATOM   4073 C C   . ALA B 1 176 ? 110.364 92.773  120.567 1.00 295.67 ?  176  ALA B C   1 
ATOM   4074 O O   . ALA B 1 176 ? 110.258 93.058  119.382 1.00 295.67 ?  176  ALA B O   1 
ATOM   4075 C CB  . ALA B 1 176 ? 112.555 92.142  121.584 1.00 295.67 ?  176  ALA B CB  1 
ATOM   4076 N N   . LEU B 1 177 ? 109.458 92.048  121.210 1.00 323.50 ?  177  LEU B N   1 
ATOM   4077 C CA  . LEU B 1 177 ? 108.281 91.536  120.520 1.00 323.50 ?  177  LEU B CA  1 
ATOM   4078 C C   . LEU B 1 177 ? 107.374 92.646  120.023 1.00 323.50 ?  177  LEU B C   1 
ATOM   4079 O O   . LEU B 1 177 ? 106.951 92.623  118.879 1.00 323.50 ?  177  LEU B O   1 
ATOM   4080 C CB  . LEU B 1 177 ? 107.490 90.592  121.420 1.00 323.50 ?  177  LEU B CB  1 
ATOM   4081 C CG  . LEU B 1 177 ? 106.640 89.553  120.694 1.00 323.50 ?  177  LEU B CG  1 
ATOM   4082 C CD1 . LEU B 1 177 ? 107.432 88.888  119.579 1.00 323.50 ?  177  LEU B CD1 1 
ATOM   4083 C CD2 . LEU B 1 177 ? 106.111 88.525  121.677 1.00 323.50 ?  177  LEU B CD2 1 
ATOM   4084 N N   . PHE B 1 178 ? 107.071 93.613  120.878 1.00 305.78 ?  178  PHE B N   1 
ATOM   4085 C CA  . PHE B 1 178 ? 106.210 94.720  120.493 1.00 305.78 ?  178  PHE B CA  1 
ATOM   4086 C C   . PHE B 1 178 ? 106.777 95.398  119.274 1.00 305.78 ?  178  PHE B C   1 
ATOM   4087 O O   . PHE B 1 178 ? 106.055 95.676  118.333 1.00 305.78 ?  178  PHE B O   1 
ATOM   4088 C CB  . PHE B 1 178 ? 106.101 95.734  121.624 1.00 305.78 ?  178  PHE B CB  1 
ATOM   4089 C CG  . PHE B 1 178 ? 104.956 96.684  121.477 1.00 305.78 ?  178  PHE B CG  1 
ATOM   4090 C CD1 . PHE B 1 178 ? 103.656 96.247  121.642 1.00 305.78 ?  178  PHE B CD1 1 
ATOM   4091 C CD2 . PHE B 1 178 ? 105.179 98.013  121.176 1.00 305.78 ?  178  PHE B CD2 1 
ATOM   4092 C CE1 . PHE B 1 178 ? 102.597 97.119  121.511 1.00 305.78 ?  178  PHE B CE1 1 
ATOM   4093 C CE2 . PHE B 1 178 ? 104.124 98.888  121.036 1.00 305.78 ?  178  PHE B CE2 1 
ATOM   4094 C CZ  . PHE B 1 178 ? 102.831 98.444  121.208 1.00 305.78 ?  178  PHE B CZ  1 
ATOM   4095 N N   . CYS B 1 179 ? 108.075 95.666  119.288 1.00 247.55 ?  179  CYS B N   1 
ATOM   4096 C CA  . CYS B 1 179 ? 108.712 96.269  118.135 1.00 247.55 ?  179  CYS B CA  1 
ATOM   4097 C C   . CYS B 1 179 ? 108.514 95.400  116.912 1.00 247.55 ?  179  CYS B C   1 
ATOM   4098 O O   . CYS B 1 179 ? 107.893 95.822  115.956 1.00 247.55 ?  179  CYS B O   1 
ATOM   4099 C CB  . CYS B 1 179 ? 110.189 96.490  118.406 1.00 247.55 ?  179  CYS B CB  1 
ATOM   4100 S SG  . CYS B 1 179 ? 110.541 98.144  119.014 1.00 247.55 ?  179  CYS B SG  1 
ATOM   4101 N N   . HIS B 1 180 ? 109.000 94.168  116.951 1.00 321.14 ?  180  HIS B N   1 
ATOM   4102 C CA  . HIS B 1 180 ? 108.840 93.251  115.829 1.00 321.14 ?  180  HIS B CA  1 
ATOM   4103 C C   . HIS B 1 180 ? 107.428 93.233  115.263 1.00 321.14 ?  180  HIS B C   1 
ATOM   4104 O O   . HIS B 1 180 ? 107.248 93.228  114.047 1.00 321.14 ?  180  HIS B O   1 
ATOM   4105 C CB  . HIS B 1 180 ? 109.230 91.840  116.254 1.00 321.14 ?  180  HIS B CB  1 
ATOM   4106 C CG  . HIS B 1 180 ? 109.638 90.959  115.117 1.00 321.14 ?  180  HIS B CG  1 
ATOM   4107 N ND1 . HIS B 1 180 ? 110.476 91.387  114.110 1.00 321.14 ?  180  HIS B ND1 1 
ATOM   4108 C CD2 . HIS B 1 180 ? 109.322 89.676  114.825 1.00 321.14 ?  180  HIS B CD2 1 
ATOM   4109 C CE1 . HIS B 1 180 ? 110.661 90.404  113.247 1.00 321.14 ?  180  HIS B CE1 1 
ATOM   4110 N NE2 . HIS B 1 180 ? 109.971 89.355  113.657 1.00 321.14 ?  180  HIS B NE2 1 
ATOM   4111 N N   . LEU B 1 181 ? 106.427 93.226  116.133 1.00 330.88 ?  181  LEU B N   1 
ATOM   4112 C CA  . LEU B 1 181 ? 105.042 93.182  115.689 1.00 330.88 ?  181  LEU B CA  1 
ATOM   4113 C C   . LEU B 1 181 ? 104.619 94.489  115.046 1.00 330.88 ?  181  LEU B C   1 
ATOM   4114 O O   . LEU B 1 181 ? 104.215 94.507  113.888 1.00 330.88 ?  181  LEU B O   1 
ATOM   4115 C CB  . LEU B 1 181 ? 104.124 92.888  116.874 1.00 330.88 ?  181  LEU B CB  1 
ATOM   4116 C CG  . LEU B 1 181 ? 103.722 91.451  117.216 1.00 330.88 ?  181  LEU B CG  1 
ATOM   4117 C CD1 . LEU B 1 181 ? 104.660 90.405  116.632 1.00 330.88 ?  181  LEU B CD1 1 
ATOM   4118 C CD2 . LEU B 1 181 ? 103.604 91.294  118.723 1.00 330.88 ?  181  LEU B CD2 1 
ATOM   4119 N N   . ILE B 1 182 ? 104.701 95.582  115.794 1.00 337.23 ?  182  ILE B N   1 
ATOM   4120 C CA  . ILE B 1 182 ? 104.279 96.880  115.276 1.00 337.23 ?  182  ILE B CA  1 
ATOM   4121 C C   . ILE B 1 182 ? 105.257 97.433  114.247 1.00 337.23 ?  182  ILE B C   1 
ATOM   4122 O O   . ILE B 1 182 ? 104.973 97.428  113.051 1.00 337.23 ?  182  ILE B O   1 
ATOM   4123 C CB  . ILE B 1 182 ? 104.073 97.898  116.413 1.00 337.23 ?  182  ILE B CB  1 
ATOM   4124 C CG1 . ILE B 1 182 ? 103.263 97.267  117.540 1.00 337.23 ?  182  ILE B CG1 1 
ATOM   4125 C CG2 . ILE B 1 182 ? 103.351 99.136  115.908 1.00 337.23 ?  182  ILE B CG2 1 
ATOM   4126 C CD1 . ILE B 1 182 ? 101.776 97.512  117.428 1.00 337.23 ?  182  ILE B CD1 1 
ATOM   4127 N N   . SER B 1 183 ? 106.407 97.909  114.701 1.00 277.75 ?  183  SER B N   1 
ATOM   4128 C CA  . SER B 1 183 ? 107.374 98.488  113.783 1.00 277.75 ?  183  SER B CA  1 
ATOM   4129 C C   . SER B 1 183 ? 108.776 97.975  114.043 1.00 277.75 ?  183  SER B C   1 
ATOM   4130 O O   . SER B 1 183 ? 109.398 98.328  115.042 1.00 277.75 ?  183  SER B O   1 
ATOM   4131 C CB  . SER B 1 183 ? 107.341 100.002 113.873 1.00 277.75 ?  183  SER B CB  1 
ATOM   4132 O OG  . SER B 1 183 ? 108.605 100.557 113.582 1.00 277.75 ?  183  SER B OG  1 
ATOM   4133 N N   . PRO B 1 184 ? 109.306 97.061  113.159 1.00 290.93 ?  184  PRO B N   1 
ATOM   4134 C CA  . PRO B 1 184 ? 110.670 96.632  113.507 1.00 290.93 ?  184  PRO B CA  1 
ATOM   4135 C C   . PRO B 1 184 ? 111.727 97.641  113.097 1.00 290.93 ?  184  PRO B C   1 
ATOM   4136 O O   . PRO B 1 184 ? 112.909 97.314  113.090 1.00 290.93 ?  184  PRO B O   1 
ATOM   4137 C CB  . PRO B 1 184 ? 110.842 95.349  112.702 1.00 290.93 ?  184  PRO B CB  1 
ATOM   4138 C CG  . PRO B 1 184 ? 110.043 95.589  111.482 1.00 290.93 ?  184  PRO B CG  1 
ATOM   4139 C CD  . PRO B 1 184 ? 108.813 96.271  111.995 1.00 290.93 ?  184  PRO B CD  1 
ATOM   4140 N N   . GLN B 1 185 ? 111.311 98.853  112.760 1.00 300.55 ?  185  GLN B N   1 
ATOM   4141 C CA  . GLN B 1 185 ? 112.258 99.897  112.401 1.00 300.55 ?  185  GLN B CA  1 
ATOM   4142 C C   . GLN B 1 185 ? 112.277 100.861 113.552 1.00 300.55 ?  185  GLN B C   1 
ATOM   4143 O O   . GLN B 1 185 ? 112.747 101.987 113.427 1.00 300.55 ?  185  GLN B O   1 
ATOM   4144 C CB  . GLN B 1 185 ? 111.866 100.591 111.095 1.00 300.55 ?  185  GLN B CB  1 
ATOM   4145 C CG  . GLN B 1 185 ? 110.376 100.768 110.874 1.00 300.55 ?  185  GLN B CG  1 
ATOM   4146 C CD  . GLN B 1 185 ? 109.764 99.651  110.051 1.00 300.55 ?  185  GLN B CD  1 
ATOM   4147 O OE1 . GLN B 1 185 ? 110.456 98.964  109.303 1.00 300.55 ?  185  GLN B OE1 1 
ATOM   4148 N NE2 . GLN B 1 185 ? 108.458 99.463  110.191 1.00 300.55 ?  185  GLN B NE2 1 
ATOM   4149 N N   . ALA B 1 186 ? 111.756 100.420 114.689 1.00 285.83 ?  186  ALA B N   1 
ATOM   4150 C CA  . ALA B 1 186 ? 111.776 101.246 115.876 1.00 285.83 ?  186  ALA B CA  1 
ATOM   4151 C C   . ALA B 1 186 ? 112.746 100.627 116.848 1.00 285.83 ?  186  ALA B C   1 
ATOM   4152 O O   . ALA B 1 186 ? 112.606 100.782 118.047 1.00 285.83 ?  186  ALA B O   1 
ATOM   4153 C CB  . ALA B 1 186 ? 110.400 101.314 116.491 1.00 285.83 ?  186  ALA B CB  1 
ATOM   4154 N N   . VAL B 1 187 ? 113.725 99.898  116.331 1.00 285.09 ?  187  VAL B N   1 
ATOM   4155 C CA  . VAL B 1 187 ? 114.722 99.283  117.187 1.00 285.09 ?  187  VAL B CA  1 
ATOM   4156 C C   . VAL B 1 187 ? 115.995 100.114 117.195 1.00 285.09 ?  187  VAL B C   1 
ATOM   4157 O O   . VAL B 1 187 ? 116.192 100.973 116.335 1.00 285.09 ?  187  VAL B O   1 
ATOM   4158 C CB  . VAL B 1 187 ? 115.020 97.829  116.766 1.00 285.09 ?  187  VAL B CB  1 
ATOM   4159 C CG1 . VAL B 1 187 ? 113.751 96.998  116.804 1.00 285.09 ?  187  VAL B CG1 1 
ATOM   4160 C CG2 . VAL B 1 187 ? 115.638 97.782  115.379 1.00 285.09 ?  187  VAL B CG2 1 
ATOM   4161 N N   . GLY B 1 188 ? 116.850 99.887  118.180 1.00 258.62 ?  188  GLY B N   1 
ATOM   4162 C CA  . GLY B 1 188 ? 118.093 100.624 118.270 1.00 258.62 ?  188  GLY B CA  1 
ATOM   4163 C C   . GLY B 1 188 ? 117.908 102.054 118.712 1.00 258.62 ?  188  GLY B C   1 
ATOM   4164 O O   . GLY B 1 188 ? 116.886 102.407 119.290 1.00 258.62 ?  188  GLY B O   1 
ATOM   4165 N N   . SER B 1 189 ? 118.890 102.906 118.433 1.00 249.74 ?  189  SER B N   1 
ATOM   4166 C CA  . SER B 1 189 ? 118.764 104.325 118.757 1.00 249.74 ?  189  SER B CA  1 
ATOM   4167 C C   . SER B 1 189 ? 118.059 105.018 117.618 1.00 249.74 ?  189  SER B C   1 
ATOM   4168 O O   . SER B 1 189 ? 117.600 104.380 116.676 1.00 249.74 ?  189  SER B O   1 
ATOM   4169 C CB  . SER B 1 189 ? 120.139 104.946 118.957 1.00 249.74 ?  189  SER B CB  1 
ATOM   4170 O OG  . SER B 1 189 ? 120.212 105.649 120.179 1.00 249.74 ?  189  SER B OG  1 
ATOM   4171 N N   . GLY B 1 190 ? 117.973 106.331 117.687 1.00 248.75 ?  190  GLY B N   1 
ATOM   4172 C CA  . GLY B 1 190 ? 117.376 107.058 116.591 1.00 248.75 ?  190  GLY B CA  1 
ATOM   4173 C C   . GLY B 1 190 ? 118.424 107.890 115.909 1.00 248.75 ?  190  GLY B C   1 
ATOM   4174 O O   . GLY B 1 190 ? 118.421 107.979 114.694 1.00 248.75 ?  190  GLY B O   1 
ATOM   4175 N N   . ILE B 1 191 ? 119.330 108.479 116.686 1.00 237.15 ?  191  ILE B N   1 
ATOM   4176 C CA  . ILE B 1 191 ? 120.394 109.312 116.126 1.00 237.15 ?  191  ILE B CA  1 
ATOM   4177 C C   . ILE B 1 191 ? 121.088 108.782 114.867 1.00 237.15 ?  191  ILE B C   1 
ATOM   4178 O O   . ILE B 1 191 ? 121.114 109.488 113.878 1.00 237.15 ?  191  ILE B O   1 
ATOM   4179 C CB  . ILE B 1 191 ? 121.452 109.737 117.172 1.00 237.15 ?  191  ILE B CB  1 
ATOM   4180 C CG1 . ILE B 1 191 ? 120.867 109.709 118.579 1.00 237.15 ?  191  ILE B CG1 1 
ATOM   4181 C CG2 . ILE B 1 191 ? 122.011 111.108 116.839 1.00 237.15 ?  191  ILE B CG2 1 
ATOM   4182 C CD1 . ILE B 1 191 ? 121.468 110.736 119.513 1.00 237.15 ?  191  ILE B CD1 1 
ATOM   4183 N N   . PRO B 1 192 ? 121.639 107.547 114.879 1.00 265.78 ?  192  PRO B N   1 
ATOM   4184 C CA  . PRO B 1 192 ? 122.307 107.135 113.634 1.00 265.78 ?  192  PRO B CA  1 
ATOM   4185 C C   . PRO B 1 192 ? 121.432 107.249 112.395 1.00 265.78 ?  192  PRO B C   1 
ATOM   4186 O O   . PRO B 1 192 ? 121.889 107.705 111.349 1.00 265.78 ?  192  PRO B O   1 
ATOM   4187 C CB  . PRO B 1 192 ? 122.622 105.663 113.878 1.00 265.78 ?  192  PRO B CB  1 
ATOM   4188 C CG  . PRO B 1 192 ? 122.699 105.524 115.347 1.00 265.78 ?  192  PRO B CG  1 
ATOM   4189 C CD  . PRO B 1 192 ? 121.715 106.489 115.907 1.00 265.78 ?  192  PRO B CD  1 
ATOM   4190 N N   . GLU B 1 193 ? 120.177 106.845 112.506 1.00 275.33 ?  193  GLU B N   1 
ATOM   4191 C CA  . GLU B 1 193 ? 119.277 106.879 111.367 1.00 275.33 ?  193  GLU B CA  1 
ATOM   4192 C C   . GLU B 1 193 ? 118.737 108.270 111.109 1.00 275.33 ?  193  GLU B C   1 
ATOM   4193 O O   . GLU B 1 193 ? 118.427 108.601 109.980 1.00 275.33 ?  193  GLU B O   1 
ATOM   4194 C CB  . GLU B 1 193 ? 118.150 105.882 111.593 1.00 275.33 ?  193  GLU B CB  1 
ATOM   4195 C CG  . GLU B 1 193 ? 118.656 104.460 111.791 1.00 275.33 ?  193  GLU B CG  1 
ATOM   4196 C CD  . GLU B 1 193 ? 118.602 103.993 113.236 1.00 275.33 ?  193  GLU B CD  1 
ATOM   4197 O OE1 . GLU B 1 193 ? 117.972 102.950 113.503 1.00 275.33 ?  193  GLU B OE1 1 
ATOM   4198 O OE2 . GLU B 1 193 ? 119.199 104.655 114.106 1.00 275.33 ?  193  GLU B OE2 1 
ATOM   4199 N N   . MET B 1 194 ? 118.646 109.099 112.142 1.00 255.21 ?  194  MET B N   1 
ATOM   4200 C CA  . MET B 1 194 ? 118.216 110.480 111.954 1.00 255.21 ?  194  MET B CA  1 
ATOM   4201 C C   . MET B 1 194 ? 119.316 111.252 111.275 1.00 255.21 ?  194  MET B C   1 
ATOM   4202 O O   . MET B 1 194 ? 119.045 112.215 110.581 1.00 255.21 ?  194  MET B O   1 
ATOM   4203 C CB  . MET B 1 194 ? 117.856 111.131 113.285 1.00 255.21 ?  194  MET B CB  1 
ATOM   4204 C CG  . MET B 1 194 ? 116.464 110.774 113.779 1.00 255.21 ?  194  MET B CG  1 
ATOM   4205 S SD  . MET B 1 194 ? 115.243 110.769 112.452 1.00 255.21 ?  194  MET B SD  1 
ATOM   4206 C CE  . MET B 1 194 ? 114.861 109.023 112.321 1.00 255.21 ?  194  MET B CE  1 
ATOM   4207 N N   . LYS B 1 195 ? 120.561 110.834 111.467 1.00 246.75 ?  195  LYS B N   1 
ATOM   4208 C CA  . LYS B 1 195 ? 121.669 111.468 110.786 1.00 246.75 ?  195  LYS B CA  1 
ATOM   4209 C C   . LYS B 1 195 ? 121.554 111.136 109.315 1.00 246.75 ?  195  LYS B C   1 
ATOM   4210 O O   . LYS B 1 195 ? 121.771 111.992 108.468 1.00 246.75 ?  195  LYS B O   1 
ATOM   4211 C CB  . LYS B 1 195 ? 122.982 110.914 111.302 1.00 246.75 ?  195  LYS B CB  1 
ATOM   4212 C CG  . LYS B 1 195 ? 123.486 111.528 112.585 1.00 246.75 ?  195  LYS B CG  1 
ATOM   4213 C CD  . LYS B 1 195 ? 124.315 110.520 113.361 1.00 246.75 ?  195  LYS B CD  1 
ATOM   4214 C CE  . LYS B 1 195 ? 125.802 110.706 113.121 1.00 246.75 ?  195  LYS B CE  1 
ATOM   4215 N NZ  . LYS B 1 195 ? 126.140 112.099 112.723 1.00 246.75 ?  195  LYS B NZ  1 
ATOM   4216 N N   . THR B 1 196 ? 121.233 109.886 109.008 1.00 271.27 ?  196  THR B N   1 
ATOM   4217 C CA  . THR B 1 196 ? 121.059 109.478 107.622 1.00 271.27 ?  196  THR B CA  1 
ATOM   4218 C C   . THR B 1 196 ? 119.941 110.284 106.976 1.00 271.27 ?  196  THR B C   1 
ATOM   4219 O O   . THR B 1 196 ? 120.125 110.846 105.898 1.00 271.27 ?  196  THR B O   1 
ATOM   4220 C CB  . THR B 1 196 ? 120.744 107.979 107.541 1.00 271.27 ?  196  THR B CB  1 
ATOM   4221 O OG1 . THR B 1 196 ? 121.700 107.257 108.325 1.00 271.27 ?  196  THR B OG1 1 
ATOM   4222 C CG2 . THR B 1 196 ? 120.794 107.487 106.116 1.00 271.27 ?  196  THR B CG2 1 
ATOM   4223 N N   . ILE B 1 197 ? 118.784 110.345 107.627 1.00 285.13 ?  197  ILE B N   1 
ATOM   4224 C CA  . ILE B 1 197 ? 117.674 111.132 107.107 1.00 285.13 ?  197  ILE B CA  1 
ATOM   4225 C C   . ILE B 1 197 ? 118.101 112.578 106.888 1.00 285.13 ?  197  ILE B C   1 
ATOM   4226 O O   . ILE B 1 197 ? 117.791 113.173 105.857 1.00 285.13 ?  197  ILE B O   1 
ATOM   4227 C CB  . ILE B 1 197 ? 116.473 111.062 108.071 1.00 285.13 ?  197  ILE B CB  1 
ATOM   4228 C CG1 . ILE B 1 197 ? 115.946 109.636 108.136 1.00 285.13 ?  197  ILE B CG1 1 
ATOM   4229 C CG2 . ILE B 1 197 ? 115.354 112.001 107.654 1.00 285.13 ?  197  ILE B CG2 1 
ATOM   4230 C CD1 . ILE B 1 197 ? 114.470 109.553 108.421 1.00 285.13 ?  197  ILE B CD1 1 
ATOM   4231 N N   . LEU B 1 198 ? 118.855 113.135 107.829 1.00 250.77 ?  198  LEU B N   1 
ATOM   4232 C CA  . LEU B 1 198 ? 119.269 114.534 107.729 1.00 250.77 ?  198  LEU B CA  1 
ATOM   4233 C C   . LEU B 1 198 ? 120.367 114.760 106.702 1.00 250.77 ?  198  LEU B C   1 
ATOM   4234 O O   . LEU B 1 198 ? 120.710 115.901 106.408 1.00 250.77 ?  198  LEU B O   1 
ATOM   4235 C CB  . LEU B 1 198 ? 119.685 115.085 109.097 1.00 250.77 ?  198  LEU B CB  1 
ATOM   4236 C CG  . LEU B 1 198 ? 118.637 115.969 109.778 1.00 250.77 ?  198  LEU B CG  1 
ATOM   4237 C CD1 . LEU B 1 198 ? 117.272 115.742 109.161 1.00 250.77 ?  198  LEU B CD1 1 
ATOM   4238 C CD2 . LEU B 1 198 ? 118.572 115.715 111.271 1.00 250.77 ?  198  LEU B CD2 1 
ATOM   4239 N N   . ARG B 1 199 ? 120.919 113.688 106.143 1.00 291.37 ?  199  ARG B N   1 
ATOM   4240 C CA  . ARG B 1 199 ? 121.913 113.830 105.088 1.00 291.37 ?  199  ARG B CA  1 
ATOM   4241 C C   . ARG B 1 199 ? 121.234 113.646 103.743 1.00 291.37 ?  199  ARG B C   1 
ATOM   4242 O O   . ARG B 1 199 ? 121.886 113.344 102.747 1.00 291.37 ?  199  ARG B O   1 
ATOM   4243 C CB  . ARG B 1 199 ? 123.052 112.829 105.272 1.00 291.37 ?  199  ARG B CB  1 
ATOM   4244 C CG  . ARG B 1 199 ? 124.432 113.444 105.111 1.00 291.37 ?  199  ARG B CG  1 
ATOM   4245 C CD  . ARG B 1 199 ? 125.200 113.473 106.418 1.00 291.37 ?  199  ARG B CD  1 
ATOM   4246 N NE  . ARG B 1 199 ? 124.307 113.570 107.566 1.00 291.37 ?  199  ARG B NE  1 
ATOM   4247 C CZ  . ARG B 1 199 ? 124.657 114.059 108.749 1.00 291.37 ?  199  ARG B CZ  1 
ATOM   4248 N NH1 . ARG B 1 199 ? 125.892 114.497 108.955 1.00 291.37 ?  199  ARG B NH1 1 
ATOM   4249 N NH2 . ARG B 1 199 ? 123.773 114.102 109.728 1.00 291.37 ?  199  ARG B NH2 1 
ATOM   4250 N N   . GLY B 1 200 ? 119.917 113.812 103.710 1.00 276.46 ?  200  GLY B N   1 
ATOM   4251 C CA  . GLY B 1 200 ? 119.184 113.710 102.463 1.00 276.46 ?  200  GLY B CA  1 
ATOM   4252 C C   . GLY B 1 200 ? 118.540 112.369 102.207 1.00 276.46 ?  200  GLY B C   1 
ATOM   4253 O O   . GLY B 1 200 ? 117.492 112.299 101.574 1.00 276.46 ?  200  GLY B O   1 
ATOM   4254 N N   . VAL B 1 201 ? 119.157 111.298 102.685 1.00 264.22 ?  201  VAL B N   1 
ATOM   4255 C CA  . VAL B 1 201 ? 118.634 109.970 102.407 1.00 264.22 ?  201  VAL B CA  1 
ATOM   4256 C C   . VAL B 1 201 ? 117.563 109.587 103.400 1.00 264.22 ?  201  VAL B C   1 
ATOM   4257 O O   . VAL B 1 201 ? 117.819 108.845 104.346 1.00 264.22 ?  201  VAL B O   1 
ATOM   4258 C CB  . VAL B 1 201 ? 119.756 108.930 102.370 1.00 264.22 ?  201  VAL B CB  1 
ATOM   4259 C CG1 . VAL B 1 201 ? 119.825 108.327 100.977 1.00 264.22 ?  201  VAL B CG1 1 
ATOM   4260 C CG2 . VAL B 1 201 ? 121.085 109.585 102.719 1.00 264.22 ?  201  VAL B CG2 1 
ATOM   4261 N N   . VAL B 1 202 ? 116.350 110.069 103.171 1.00 240.15 ?  202  VAL B N   1 
ATOM   4262 C CA  . VAL B 1 202 ? 115.269 109.829 104.116 1.00 240.15 ?  202  VAL B CA  1 
ATOM   4263 C C   . VAL B 1 202 ? 114.633 108.447 104.040 1.00 240.15 ?  202  VAL B C   1 
ATOM   4264 O O   . VAL B 1 202 ? 114.173 108.018 102.980 1.00 240.15 ?  202  VAL B O   1 
ATOM   4265 C CB  . VAL B 1 202 ? 114.208 110.958 104.014 1.00 240.15 ?  202  VAL B CB  1 
ATOM   4266 C CG1 . VAL B 1 202 ? 113.931 111.332 102.566 1.00 240.15 ?  202  VAL B CG1 1 
ATOM   4267 C CG2 . VAL B 1 202 ? 112.930 110.623 104.770 1.00 240.15 ?  202  VAL B CG2 1 
ATOM   4268 N N   . LEU B 1 203 ? 114.646 107.723 105.153 1.00 252.28 ?  203  LEU B N   1 
ATOM   4269 C CA  . LEU B 1 203 ? 113.980 106.434 105.198 1.00 252.28 ?  203  LEU B CA  1 
ATOM   4270 C C   . LEU B 1 203 ? 112.608 106.787 105.717 1.00 252.28 ?  203  LEU B C   1 
ATOM   4271 O O   . LEU B 1 203 ? 112.485 107.341 106.803 1.00 252.28 ?  203  LEU B O   1 
ATOM   4272 C CB  . LEU B 1 203 ? 114.703 105.501 106.160 1.00 252.28 ?  203  LEU B CB  1 
ATOM   4273 C CG  . LEU B 1 203 ? 116.063 105.989 106.670 1.00 252.28 ?  203  LEU B CG  1 
ATOM   4274 C CD1 . LEU B 1 203 ? 116.218 105.696 108.152 1.00 252.28 ?  203  LEU B CD1 1 
ATOM   4275 C CD2 . LEU B 1 203 ? 117.213 105.382 105.880 1.00 252.28 ?  203  LEU B CD2 1 
ATOM   4276 N N   . LYS B 1 204 ? 111.562 106.494 104.959 1.00 266.35 ?  204  LYS B N   1 
ATOM   4277 C CA  . LYS B 1 204 ? 110.230 106.936 105.375 1.00 266.35 ?  204  LYS B CA  1 
ATOM   4278 C C   . LYS B 1 204 ? 109.425 105.985 106.250 1.00 266.35 ?  204  LYS B C   1 
ATOM   4279 O O   . LYS B 1 204 ? 108.246 106.227 106.497 1.00 266.35 ?  204  LYS B O   1 
ATOM   4280 C CB  . LYS B 1 204 ? 109.405 107.385 104.165 1.00 266.35 ?  204  LYS B CB  1 
ATOM   4281 C CG  . LYS B 1 204 ? 109.104 108.878 104.141 1.00 266.35 ?  204  LYS B CG  1 
ATOM   4282 C CD  . LYS B 1 204 ? 109.292 109.527 105.507 1.00 266.35 ?  204  LYS B CD  1 
ATOM   4283 C CE  . LYS B 1 204 ? 107.978 110.041 106.074 1.00 266.35 ?  204  LYS B CE  1 
ATOM   4284 N NZ  . LYS B 1 204 ? 107.362 109.070 107.019 1.00 266.35 ?  204  LYS B NZ  1 
ATOM   4285 N N   . GLU B 1 205 ? 110.034 104.908 106.724 1.00 287.44 ?  205  GLU B N   1 
ATOM   4286 C CA  . GLU B 1 205 ? 109.321 104.043 107.654 1.00 287.44 ?  205  GLU B CA  1 
ATOM   4287 C C   . GLU B 1 205 ? 109.805 104.426 109.027 1.00 287.44 ?  205  GLU B C   1 
ATOM   4288 O O   . GLU B 1 205 ? 109.233 104.030 110.038 1.00 287.44 ?  205  GLU B O   1 
ATOM   4289 C CB  . GLU B 1 205 ? 109.575 102.573 107.360 1.00 287.44 ?  205  GLU B CB  1 
ATOM   4290 C CG  . GLU B 1 205 ? 108.295 101.764 107.269 1.00 287.44 ?  205  GLU B CG  1 
ATOM   4291 C CD  . GLU B 1 205 ? 108.370 100.678 106.220 1.00 287.44 ?  205  GLU B CD  1 
ATOM   4292 O OE1 . GLU B 1 205 ? 107.984 99.531  106.525 1.00 287.44 ?  205  GLU B OE1 1 
ATOM   4293 O OE2 . GLU B 1 205 ? 108.814 100.974 105.092 1.00 287.44 ?  205  GLU B OE2 1 
ATOM   4294 N N   . TYR B 1 206 ? 110.837 105.242 109.075 1.00 270.14 ?  206  TYR B N   1 
ATOM   4295 C CA  . TYR B 1 206 ? 111.323 105.670 110.360 1.00 270.14 ?  206  TYR B CA  1 
ATOM   4296 C C   . TYR B 1 206 ? 110.390 106.689 110.971 1.00 270.14 ?  206  TYR B C   1 
ATOM   4297 O O   . TYR B 1 206 ? 110.080 106.627 112.155 1.00 270.14 ?  206  TYR B O   1 
ATOM   4298 C CB  . TYR B 1 206 ? 112.751 106.146 110.283 1.00 270.14 ?  206  TYR B CB  1 
ATOM   4299 C CG  . TYR B 1 206 ? 113.645 104.990 110.575 1.00 270.14 ?  206  TYR B CG  1 
ATOM   4300 C CD1 . TYR B 1 206 ? 113.733 103.922 109.690 1.00 270.14 ?  206  TYR B CD1 1 
ATOM   4301 C CD2 . TYR B 1 206 ? 114.338 104.916 111.760 1.00 270.14 ?  206  TYR B CD2 1 
ATOM   4302 C CE1 . TYR B 1 206 ? 114.541 102.843 109.951 1.00 270.14 ?  206  TYR B CE1 1 
ATOM   4303 C CE2 . TYR B 1 206 ? 115.132 103.835 112.036 1.00 270.14 ?  206  TYR B CE2 1 
ATOM   4304 C CZ  . TYR B 1 206 ? 115.235 102.802 111.127 1.00 270.14 ?  206  TYR B CZ  1 
ATOM   4305 O OH  . TYR B 1 206 ? 116.031 101.715 111.397 1.00 270.14 ?  206  TYR B OH  1 
ATOM   4306 N N   . LEU B 1 207 ? 109.911 107.613 110.155 1.00 249.20 ?  207  LEU B N   1 
ATOM   4307 C CA  . LEU B 1 207 ? 109.033 108.640 110.702 1.00 249.20 ?  207  LEU B CA  1 
ATOM   4308 C C   . LEU B 1 207 ? 107.562 108.293 110.581 1.00 249.20 ?  207  LEU B C   1 
ATOM   4309 O O   . LEU B 1 207 ? 106.773 109.111 110.120 1.00 249.20 ?  207  LEU B O   1 
ATOM   4310 C CB  . LEU B 1 207 ? 109.295 109.981 110.018 1.00 249.20 ?  207  LEU B CB  1 
ATOM   4311 C CG  . LEU B 1 207 ? 110.291 110.946 110.658 1.00 249.20 ?  207  LEU B CG  1 
ATOM   4312 C CD1 . LEU B 1 207 ? 110.935 110.351 111.896 1.00 249.20 ?  207  LEU B CD1 1 
ATOM   4313 C CD2 . LEU B 1 207 ? 111.350 111.337 109.646 1.00 249.20 ?  207  LEU B CD2 1 
ATOM   4314 N N   . THR B 1 208 ? 107.180 107.090 110.995 1.00 277.04 ?  208  THR B N   1 
ATOM   4315 C CA  . THR B 1 208 ? 105.775 106.710 110.971 1.00 277.04 ?  208  THR B CA  1 
ATOM   4316 C C   . THR B 1 208 ? 105.198 106.685 112.373 1.00 277.04 ?  208  THR B C   1 
ATOM   4317 O O   . THR B 1 208 ? 105.937 106.700 113.348 1.00 277.04 ?  208  THR B O   1 
ATOM   4318 C CB  . THR B 1 208 ? 105.564 105.328 110.339 1.00 277.04 ?  208  THR B CB  1 
ATOM   4319 O OG1 . THR B 1 208 ? 106.484 104.392 110.911 1.00 277.04 ?  208  THR B OG1 1 
ATOM   4320 C CG2 . THR B 1 208 ? 105.770 105.389 108.842 1.00 277.04 ?  208  THR B CG2 1 
ATOM   4321 N N   . MET B 1 209 ? 103.877 106.624 112.478 1.00 249.61 ?  209  MET B N   1 
ATOM   4322 C CA  . MET B 1 209 ? 103.231 106.577 113.782 1.00 249.61 ?  209  MET B CA  1 
ATOM   4323 C C   . MET B 1 209 ? 103.325 105.193 114.383 1.00 249.61 ?  209  MET B C   1 
ATOM   4324 O O   . MET B 1 209 ? 103.231 105.035 115.593 1.00 249.61 ?  209  MET B O   1 
ATOM   4325 C CB  . MET B 1 209 ? 101.769 106.997 113.677 1.00 249.61 ?  209  MET B CB  1 
ATOM   4326 C CG  . MET B 1 209 ? 101.508 108.439 114.078 1.00 249.61 ?  209  MET B CG  1 
ATOM   4327 S SD  . MET B 1 209 ? 102.102 108.833 115.734 1.00 249.61 ?  209  MET B SD  1 
ATOM   4328 C CE  . MET B 1 209 ? 100.944 107.915 116.744 1.00 249.61 ?  209  MET B CE  1 
ATOM   4329 N N   . LYS B 1 210 ? 103.503 104.181 113.548 1.00 257.56 ?  210  LYS B N   1 
ATOM   4330 C CA  . LYS B 1 210 ? 103.688 102.836 114.064 1.00 257.56 ?  210  LYS B CA  1 
ATOM   4331 C C   . LYS B 1 210 ? 105.016 102.828 114.780 1.00 257.56 ?  210  LYS B C   1 
ATOM   4332 O O   . LYS B 1 210 ? 105.125 102.289 115.876 1.00 257.56 ?  210  LYS B O   1 
ATOM   4333 C CB  . LYS B 1 210 ? 103.689 101.817 112.931 1.00 257.56 ?  210  LYS B CB  1 
ATOM   4334 C CG  . LYS B 1 210 ? 103.274 102.388 111.586 1.00 257.56 ?  210  LYS B CG  1 
ATOM   4335 C CD  . LYS B 1 210 ? 101.830 102.046 111.255 1.00 257.56 ?  210  LYS B CD  1 
ATOM   4336 C CE  . LYS B 1 210 ? 101.001 103.301 111.021 1.00 257.56 ?  210  LYS B CE  1 
ATOM   4337 N NZ  . LYS B 1 210 ? 101.845 104.464 110.629 1.00 257.56 ?  210  LYS B NZ  1 
ATOM   4338 N N   . ALA B 1 211 ? 106.025 103.447 114.176 1.00 269.25 ?  211  ALA B N   1 
ATOM   4339 C CA  . ALA B 1 211 ? 107.323 103.543 114.820 1.00 269.25 ?  211  ALA B CA  1 
ATOM   4340 C C   . ALA B 1 211 ? 107.211 104.270 116.137 1.00 269.25 ?  211  ALA B C   1 
ATOM   4341 O O   . ALA B 1 211 ? 107.825 103.861 117.107 1.00 269.25 ?  211  ALA B O   1 
ATOM   4342 C CB  . ALA B 1 211 ? 108.320 104.235 113.916 1.00 269.25 ?  211  ALA B CB  1 
ATOM   4343 N N   . PHE B 1 212 ? 106.426 105.342 116.180 1.00 256.48 ?  212  PHE B N   1 
ATOM   4344 C CA  . PHE B 1 212 ? 106.228 106.084 117.413 1.00 256.48 ?  212  PHE B CA  1 
ATOM   4345 C C   . PHE B 1 212 ? 105.739 105.166 118.497 1.00 256.48 ?  212  PHE B C   1 
ATOM   4346 O O   . PHE B 1 212 ? 106.407 104.998 119.500 1.00 256.48 ?  212  PHE B O   1 
ATOM   4347 C CB  . PHE B 1 212 ? 105.214 107.196 117.207 1.00 256.48 ?  212  PHE B CB  1 
ATOM   4348 C CG  . PHE B 1 212 ? 105.178 108.201 118.317 1.00 256.48 ?  212  PHE B CG  1 
ATOM   4349 C CD1 . PHE B 1 212 ? 106.219 109.091 118.494 1.00 256.48 ?  212  PHE B CD1 1 
ATOM   4350 C CD2 . PHE B 1 212 ? 104.099 108.258 119.181 1.00 256.48 ?  212  PHE B CD2 1 
ATOM   4351 C CE1 . PHE B 1 212 ? 106.185 110.021 119.509 1.00 256.48 ?  212  PHE B CE1 1 
ATOM   4352 C CE2 . PHE B 1 212 ? 104.062 109.185 120.202 1.00 256.48 ?  212  PHE B CE2 1 
ATOM   4353 C CZ  . PHE B 1 212 ? 105.108 110.067 120.367 1.00 256.48 ?  212  PHE B CZ  1 
ATOM   4354 N N   . VAL B 1 213 ? 104.575 104.568 118.295 1.00 248.50 ?  213  VAL B N   1 
ATOM   4355 C CA  . VAL B 1 213 ? 104.000 103.686 119.300 1.00 248.50 ?  213  VAL B CA  1 
ATOM   4356 C C   . VAL B 1 213 ? 104.995 102.623 119.738 1.00 248.50 ?  213  VAL B C   1 
ATOM   4357 O O   . VAL B 1 213 ? 105.249 102.473 120.925 1.00 248.50 ?  213  VAL B O   1 
ATOM   4358 C CB  . VAL B 1 213 ? 102.695 103.040 118.798 1.00 248.50 ?  213  VAL B CB  1 
ATOM   4359 C CG1 . VAL B 1 213 ? 102.125 102.079 119.827 1.00 248.50 ?  213  VAL B CG1 1 
ATOM   4360 C CG2 . VAL B 1 213 ? 101.675 104.119 118.478 1.00 248.50 ?  213  VAL B CG2 1 
ATOM   4361 N N   . ALA B 1 214 ? 105.582 101.909 118.783 1.00 277.83 ?  214  ALA B N   1 
ATOM   4362 C CA  . ALA B 1 214 ? 106.535 100.865 119.118 1.00 277.83 ?  214  ALA B CA  1 
ATOM   4363 C C   . ALA B 1 214 ? 107.637 101.410 119.999 1.00 277.83 ?  214  ALA B C   1 
ATOM   4364 O O   . ALA B 1 214 ? 107.811 100.950 121.114 1.00 277.83 ?  214  ALA B O   1 
ATOM   4365 C CB  . ALA B 1 214 ? 107.110 100.232 117.868 1.00 277.83 ?  214  ALA B CB  1 
ATOM   4366 N N   . LYS B 1 215 ? 108.355 102.418 119.517 1.00 263.72 ?  215  LYS B N   1 
ATOM   4367 C CA  . LYS B 1 215 ? 109.447 103.003 120.283 1.00 263.72 ?  215  LYS B CA  1 
ATOM   4368 C C   . LYS B 1 215 ? 109.007 103.459 121.663 1.00 263.72 ?  215  LYS B C   1 
ATOM   4369 O O   . LYS B 1 215 ? 109.658 103.139 122.641 1.00 263.72 ?  215  LYS B O   1 
ATOM   4370 C CB  . LYS B 1 215 ? 110.085 104.161 119.521 1.00 263.72 ?  215  LYS B CB  1 
ATOM   4371 C CG  . LYS B 1 215 ? 111.574 104.316 119.768 1.00 263.72 ?  215  LYS B CG  1 
ATOM   4372 C CD  . LYS B 1 215 ? 112.360 104.073 118.497 1.00 263.72 ?  215  LYS B CD  1 
ATOM   4373 C CE  . LYS B 1 215 ? 113.857 104.077 118.743 1.00 263.72 ?  215  LYS B CE  1 
ATOM   4374 N NZ  . LYS B 1 215 ? 114.624 103.759 117.508 1.00 263.72 ?  215  LYS B NZ  1 
ATOM   4375 N N   . VAL B 1 216 ? 107.910 104.201 121.748 1.00 243.99 ?  216  VAL B N   1 
ATOM   4376 C CA  . VAL B 1 216 ? 107.436 104.713 123.034 1.00 243.99 ?  216  VAL B CA  1 
ATOM   4377 C C   . VAL B 1 216 ? 107.205 103.591 124.034 1.00 243.99 ?  216  VAL B C   1 
ATOM   4378 O O   . VAL B 1 216 ? 107.868 103.540 125.065 1.00 243.99 ?  216  VAL B O   1 
ATOM   4379 C CB  . VAL B 1 216 ? 106.158 105.580 122.893 1.00 243.99 ?  216  VAL B CB  1 
ATOM   4380 C CG1 . VAL B 1 216 ? 105.523 105.862 124.246 1.00 243.99 ?  216  VAL B CG1 1 
ATOM   4381 C CG2 . VAL B 1 216 ? 106.488 106.894 122.216 1.00 243.99 ?  216  VAL B CG2 1 
ATOM   4382 N N   . VAL B 1 217 ? 106.306 102.668 123.722 1.00 240.87 ?  217  VAL B N   1 
ATOM   4383 C CA  . VAL B 1 217 ? 105.971 101.609 124.663 1.00 240.87 ?  217  VAL B CA  1 
ATOM   4384 C C   . VAL B 1 217 ? 107.160 100.724 124.982 1.00 240.87 ?  217  VAL B C   1 
ATOM   4385 O O   . VAL B 1 217 ? 107.418 100.409 126.141 1.00 240.87 ?  217  VAL B O   1 
ATOM   4386 C CB  . VAL B 1 217 ? 104.786 100.771 124.146 1.00 240.87 ?  217  VAL B CB  1 
ATOM   4387 C CG1 . VAL B 1 217 ? 104.284 99.825  125.218 1.00 240.87 ?  217  VAL B CG1 1 
ATOM   4388 C CG2 . VAL B 1 217 ? 103.651 101.688 123.726 1.00 240.87 ?  217  VAL B CG2 1 
ATOM   4389 N N   . ALA B 1 218 ? 107.912 100.345 123.963 1.00 248.37 ?  218  ALA B N   1 
ATOM   4390 C CA  . ALA B 1 218 ? 109.042 99.459  124.177 1.00 248.37 ?  218  ALA B CA  1 
ATOM   4391 C C   . ALA B 1 218 ? 110.184 100.105 124.952 1.00 248.37 ?  218  ALA B C   1 
ATOM   4392 O O   . ALA B 1 218 ? 110.870 99.434  125.711 1.00 248.37 ?  218  ALA B O   1 
ATOM   4393 C CB  . ALA B 1 218 ? 109.521 98.915  122.855 1.00 248.37 ?  218  ALA B CB  1 
ATOM   4394 N N   . LEU B 1 219 ? 110.388 101.403 124.781 1.00 254.00 ?  219  LEU B N   1 
ATOM   4395 C CA  . LEU B 1 219 ? 111.409 102.091 125.548 1.00 254.00 ?  219  LEU B CA  1 
ATOM   4396 C C   . LEU B 1 219 ? 110.989 102.181 126.996 1.00 254.00 ?  219  LEU B C   1 
ATOM   4397 O O   . LEU B 1 219 ? 111.797 101.958 127.873 1.00 254.00 ?  219  LEU B O   1 
ATOM   4398 C CB  . LEU B 1 219 ? 111.646 103.484 125.000 1.00 254.00 ?  219  LEU B CB  1 
ATOM   4399 C CG  . LEU B 1 219 ? 112.848 104.279 125.478 1.00 254.00 ?  219  LEU B CG  1 
ATOM   4400 C CD1 . LEU B 1 219 ? 114.137 103.519 125.235 1.00 254.00 ?  219  LEU B CD1 1 
ATOM   4401 C CD2 . LEU B 1 219 ? 112.844 105.584 124.723 1.00 254.00 ?  219  LEU B CD2 1 
ATOM   4402 N N   . THR B 1 220 ? 109.724 102.487 127.258 1.00 260.38 ?  220  THR B N   1 
ATOM   4403 C CA  . THR B 1 220 ? 109.235 102.505 128.631 1.00 260.38 ?  220  THR B CA  1 
ATOM   4404 C C   . THR B 1 220 ? 109.535 101.181 129.318 1.00 260.38 ?  220  THR B C   1 
ATOM   4405 O O   . THR B 1 220 ? 110.029 101.156 130.444 1.00 260.38 ?  220  THR B O   1 
ATOM   4406 C CB  . THR B 1 220 ? 107.721 102.757 128.690 1.00 260.38 ?  220  THR B CB  1 
ATOM   4407 O OG1 . THR B 1 220 ? 107.357 103.730 127.712 1.00 260.38 ?  220  THR B OG1 1 
ATOM   4408 C CG2 . THR B 1 220 ? 107.328 103.261 130.046 1.00 260.38 ?  220  THR B CG2 1 
ATOM   4409 N N   . ALA B 1 221 ? 109.255 100.076 128.638 1.00 244.81 ?  221  ALA B N   1 
ATOM   4410 C CA  . ALA B 1 221 ? 109.520 98.764  129.205 1.00 244.81 ?  221  ALA B CA  1 
ATOM   4411 C C   . ALA B 1 221 ? 111.006 98.533  129.422 1.00 244.81 ?  221  ALA B C   1 
ATOM   4412 O O   . ALA B 1 221 ? 111.404 97.997  130.448 1.00 244.81 ?  221  ALA B O   1 
ATOM   4413 C CB  . ALA B 1 221 ? 108.931 97.688  128.317 1.00 244.81 ?  221  ALA B CB  1 
ATOM   4414 N N   . GLY B 1 222 ? 111.832 98.944  128.471 1.00 244.62 ?  222  GLY B N   1 
ATOM   4415 C CA  . GLY B 1 222 ? 113.268 98.803  128.617 1.00 244.62 ?  222  GLY B CA  1 
ATOM   4416 C C   . GLY B 1 222 ? 113.870 99.637  129.730 1.00 244.62 ?  222  GLY B C   1 
ATOM   4417 O O   . GLY B 1 222 ? 114.853 99.238  130.340 1.00 244.62 ?  222  GLY B O   1 
ATOM   4418 N N   . LEU B 1 223 ? 113.289 100.798 130.007 1.00 242.33 ?  223  LEU B N   1 
ATOM   4419 C CA  . LEU B 1 223 ? 113.800 101.661 131.062 1.00 242.33 ?  223  LEU B CA  1 
ATOM   4420 C C   . LEU B 1 223 ? 113.279 101.256 132.419 1.00 242.33 ?  223  LEU B C   1 
ATOM   4421 O O   . LEU B 1 223 ? 113.844 101.636 133.435 1.00 242.33 ?  223  LEU B O   1 
ATOM   4422 C CB  . LEU B 1 223 ? 113.435 103.115 130.807 1.00 242.33 ?  223  LEU B CB  1 
ATOM   4423 C CG  . LEU B 1 223 ? 113.919 103.793 129.537 1.00 242.33 ?  223  LEU B CG  1 
ATOM   4424 C CD1 . LEU B 1 223 ? 112.999 104.971 129.267 1.00 242.33 ?  223  LEU B CD1 1 
ATOM   4425 C CD2 . LEU B 1 223 ? 115.370 104.222 129.668 1.00 242.33 ?  223  LEU B CD2 1 
ATOM   4426 N N   . GLY B 1 224 ? 112.199 100.490 132.445 1.00 257.32 ?  224  GLY B N   1 
ATOM   4427 C CA  . GLY B 1 224 ? 111.651 100.024 133.699 1.00 257.32 ?  224  GLY B CA  1 
ATOM   4428 C C   . GLY B 1 224 ? 112.156 98.645  134.026 1.00 257.32 ?  224  GLY B C   1 
ATOM   4429 O O   . GLY B 1 224 ? 111.703 98.023  134.981 1.00 257.32 ?  224  GLY B O   1 
ATOM   4430 N N   . SER B 1 225 ? 113.098 98.154  133.235 1.00 236.65 ?  225  SER B N   1 
ATOM   4431 C CA  . SER B 1 225 ? 113.659 96.840  133.477 1.00 236.65 ?  225  SER B CA  1 
ATOM   4432 C C   . SER B 1 225 ? 114.913 96.930  134.324 1.00 236.65 ?  225  SER B C   1 
ATOM   4433 O O   . SER B 1 225 ? 115.193 96.034  135.114 1.00 236.65 ?  225  SER B O   1 
ATOM   4434 C CB  . SER B 1 225 ? 113.963 96.146  132.156 1.00 236.65 ?  225  SER B CB  1 
ATOM   4435 O OG  . SER B 1 225 ? 115.057 96.753  131.506 1.00 236.65 ?  225  SER B OG  1 
ATOM   4436 N N   . GLY B 1 226 ? 115.676 98.004  134.168 1.00 225.32 ?  226  GLY B N   1 
ATOM   4437 C CA  . GLY B 1 226 ? 116.923 98.137  134.898 1.00 225.32 ?  226  GLY B CA  1 
ATOM   4438 C C   . GLY B 1 226 ? 118.102 97.641  134.094 1.00 225.32 ?  226  GLY B C   1 
ATOM   4439 O O   . GLY B 1 226 ? 119.233 97.678  134.565 1.00 225.32 ?  226  GLY B O   1 
ATOM   4440 N N   . ILE B 1 227 ? 117.845 97.174  132.879 1.00 196.92 ?  227  ILE B N   1 
ATOM   4441 C CA  . ILE B 1 227 ? 118.906 96.692  132.009 1.00 196.92 ?  227  ILE B CA  1 
ATOM   4442 C C   . ILE B 1 227 ? 119.514 97.941  131.415 1.00 196.92 ?  227  ILE B C   1 
ATOM   4443 O O   . ILE B 1 227 ? 118.775 98.856  131.075 1.00 196.92 ?  227  ILE B O   1 
ATOM   4444 C CB  . ILE B 1 227 ? 118.320 95.758  130.923 1.00 196.92 ?  227  ILE B CB  1 
ATOM   4445 C CG1 . ILE B 1 227 ? 117.747 94.501  131.573 1.00 196.92 ?  227  ILE B CG1 1 
ATOM   4446 C CG2 . ILE B 1 227 ? 119.345 95.360  129.874 1.00 196.92 ?  227  ILE B CG2 1 
ATOM   4447 C CD1 . ILE B 1 227 ? 118.727 93.754  132.448 1.00 196.92 ?  227  ILE B CD1 1 
ATOM   4448 N N   . PRO B 1 228 ? 120.893 98.016  131.293 1.00 174.25 ?  228  PRO B N   1 
ATOM   4449 C CA  . PRO B 1 228 ? 121.414 99.291  130.769 1.00 174.25 ?  228  PRO B CA  1 
ATOM   4450 C C   . PRO B 1 228 ? 121.113 99.628  129.323 1.00 174.25 ?  228  PRO B C   1 
ATOM   4451 O O   . PRO B 1 228 ? 121.962 99.428  128.458 1.00 174.25 ?  228  PRO B O   1 
ATOM   4452 C CB  . PRO B 1 228 ? 122.928 99.154  130.946 1.00 174.25 ?  228  PRO B CB  1 
ATOM   4453 C CG  . PRO B 1 228 ? 123.191 97.698  130.981 1.00 174.25 ?  228  PRO B CG  1 
ATOM   4454 C CD  . PRO B 1 228 ? 122.034 97.165  131.745 1.00 174.25 ?  228  PRO B CD  1 
ATOM   4455 N N   . VAL B 1 229 ? 119.924 100.152 129.051 1.00 202.83 ?  229  VAL B N   1 
ATOM   4456 C CA  . VAL B 1 229 ? 119.583 100.608 127.712 1.00 202.83 ?  229  VAL B CA  1 
ATOM   4457 C C   . VAL B 1 229 ? 119.420 102.097 127.938 1.00 202.83 ?  229  VAL B C   1 
ATOM   4458 O O   . VAL B 1 229 ? 119.346 102.544 129.085 1.00 202.83 ?  229  VAL B O   1 
ATOM   4459 C CB  . VAL B 1 229 ? 118.300 99.948  127.173 1.00 202.83 ?  229  VAL B CB  1 
ATOM   4460 C CG1 . VAL B 1 229 ? 118.383 98.438  127.319 1.00 202.83 ?  229  VAL B CG1 1 
ATOM   4461 C CG2 . VAL B 1 229 ? 117.057 100.487 127.863 1.00 202.83 ?  229  VAL B CG2 1 
ATOM   4462 N N   . GLY B 1 230 ? 119.377 102.894 126.884 1.00 199.38 ?  230  GLY B N   1 
ATOM   4463 C CA  . GLY B 1 230 ? 119.317 104.328 127.090 1.00 199.38 ?  230  GLY B CA  1 
ATOM   4464 C C   . GLY B 1 230 ? 118.062 104.999 126.607 1.00 199.38 ?  230  GLY B C   1 
ATOM   4465 O O   . GLY B 1 230 ? 117.453 104.558 125.638 1.00 199.38 ?  230  GLY B O   1 
ATOM   4466 N N   . LYS B 1 231 ? 117.659 106.065 127.282 1.00 223.11 ?  231  LYS B N   1 
ATOM   4467 C CA  . LYS B 1 231 ? 116.508 106.820 126.829 1.00 223.11 ?  231  LYS B CA  1 
ATOM   4468 C C   . LYS B 1 231 ? 117.015 107.814 125.814 1.00 223.11 ?  231  LYS B C   1 
ATOM   4469 O O   . LYS B 1 231 ? 116.371 108.056 124.801 1.00 223.11 ?  231  LYS B O   1 
ATOM   4470 C CB  . LYS B 1 231 ? 115.870 107.556 127.998 1.00 223.11 ?  231  LYS B CB  1 
ATOM   4471 C CG  . LYS B 1 231 ? 116.804 107.788 129.171 1.00 223.11 ?  231  LYS B CG  1 
ATOM   4472 C CD  . LYS B 1 231 ? 116.144 108.681 130.203 1.00 223.11 ?  231  LYS B CD  1 
ATOM   4473 C CE  . LYS B 1 231 ? 114.638 108.716 130.010 1.00 223.11 ?  231  LYS B CE  1 
ATOM   4474 N NZ  . LYS B 1 231 ? 114.081 110.087 130.168 1.00 223.11 ?  231  LYS B NZ  1 
ATOM   4475 N N   . GLU B 1 232 ? 118.182 108.389 126.079 1.00 245.05 ?  232  GLU B N   1 
ATOM   4476 C CA  . GLU B 1 232 ? 118.771 109.368 125.173 1.00 245.05 ?  232  GLU B CA  1 
ATOM   4477 C C   . GLU B 1 232 ? 119.226 108.713 123.897 1.00 245.05 ?  232  GLU B C   1 
ATOM   4478 O O   . GLU B 1 232 ? 120.151 107.902 123.905 1.00 245.05 ?  232  GLU B O   1 
ATOM   4479 C CB  . GLU B 1 232 ? 119.938 110.043 125.865 1.00 245.05 ?  232  GLU B CB  1 
ATOM   4480 C CG  . GLU B 1 232 ? 120.009 109.702 127.343 1.00 245.05 ?  232  GLU B CG  1 
ATOM   4481 C CD  . GLU B 1 232 ? 119.666 110.891 128.199 1.00 245.05 ?  232  GLU B CD  1 
ATOM   4482 O OE1 . GLU B 1 232 ? 119.581 110.750 129.436 1.00 245.05 ?  232  GLU B OE1 1 
ATOM   4483 O OE2 . GLU B 1 232 ? 119.472 111.970 127.611 1.00 245.05 ?  232  GLU B OE2 1 
ATOM   4484 N N   . GLY B 1 233 ? 118.591 109.067 122.789 1.00 234.26 ?  233  GLY B N   1 
ATOM   4485 C CA  . GLY B 1 233 ? 118.903 108.412 121.539 1.00 234.26 ?  233  GLY B CA  1 
ATOM   4486 C C   . GLY B 1 233 ? 117.594 107.981 120.931 1.00 234.26 ?  233  GLY B C   1 
ATOM   4487 O O   . GLY B 1 233 ? 117.254 108.418 119.848 1.00 234.26 ?  233  GLY B O   1 
ATOM   4488 N N   . PRO B 1 234 ? 116.860 107.088 121.608 1.00 242.17 ?  234  PRO B N   1 
ATOM   4489 C CA  . PRO B 1 234 ? 115.533 106.766 121.081 1.00 242.17 ?  234  PRO B CA  1 
ATOM   4490 C C   . PRO B 1 234 ? 114.555 107.916 121.279 1.00 242.17 ?  234  PRO B C   1 
ATOM   4491 O O   . PRO B 1 234 ? 113.668 108.079 120.450 1.00 242.17 ?  234  PRO B O   1 
ATOM   4492 C CB  . PRO B 1 234 ? 115.118 105.562 121.918 1.00 242.17 ?  234  PRO B CB  1 
ATOM   4493 C CG  . PRO B 1 234 ? 116.399 104.902 122.263 1.00 242.17 ?  234  PRO B CG  1 
ATOM   4494 C CD  . PRO B 1 234 ? 117.362 106.027 122.497 1.00 242.17 ?  234  PRO B CD  1 
ATOM   4495 N N   . PHE B 1 235 ? 114.699 108.689 122.351 1.00 250.74 ?  235  PHE B N   1 
ATOM   4496 C CA  . PHE B 1 235 ? 113.846 109.859 122.555 1.00 250.74 ?  235  PHE B CA  1 
ATOM   4497 C C   . PHE B 1 235 ? 113.987 110.702 121.316 1.00 250.74 ?  235  PHE B C   1 
ATOM   4498 O O   . PHE B 1 235 ? 113.002 111.191 120.790 1.00 250.74 ?  235  PHE B O   1 
ATOM   4499 C CB  . PHE B 1 235 ? 114.265 110.641 123.789 1.00 250.74 ?  235  PHE B CB  1 
ATOM   4500 C CG  . PHE B 1 235 ? 113.496 110.272 125.016 1.00 250.74 ?  235  PHE B CG  1 
ATOM   4501 C CD1 . PHE B 1 235 ? 113.367 108.951 125.396 1.00 250.74 ?  235  PHE B CD1 1 
ATOM   4502 C CD2 . PHE B 1 235 ? 112.894 111.240 125.783 1.00 250.74 ?  235  PHE B CD2 1 
ATOM   4503 C CE1 . PHE B 1 235 ? 112.660 108.601 126.527 1.00 250.74 ?  235  PHE B CE1 1 
ATOM   4504 C CE2 . PHE B 1 235 ? 112.191 110.896 126.915 1.00 250.74 ?  235  PHE B CE2 1 
ATOM   4505 C CZ  . PHE B 1 235 ? 112.067 109.578 127.288 1.00 250.74 ?  235  PHE B CZ  1 
ATOM   4506 N N   . VAL B 1 236 ? 115.211 110.922 120.870 1.00 259.83 ?  236  VAL B N   1 
ATOM   4507 C CA  . VAL B 1 236 ? 115.407 111.603 119.564 1.00 259.83 ?  236  VAL B CA  1 
ATOM   4508 C C   . VAL B 1 236 ? 115.147 110.622 118.446 1.00 259.83 ?  236  VAL B C   1 
ATOM   4509 O O   . VAL B 1 236 ? 116.063 109.936 117.971 1.00 259.83 ?  236  VAL B O   1 
ATOM   4510 C CB  . VAL B 1 236 ? 116.563 112.638 119.180 1.00 259.83 ?  236  VAL B CB  1 
ATOM   4511 C CG1 . VAL B 1 236 ? 118.069 112.230 119.145 1.00 259.83 ?  236  VAL B CG1 1 
ATOM   4512 C CG2 . VAL B 1 236 ? 116.270 112.970 117.731 1.00 259.83 ?  236  VAL B CG2 1 
ATOM   4513 N N   . HIS B 1 237 ? 113.883 110.471 118.112 1.00 254.65 ?  237  HIS B N   1 
ATOM   4514 C CA  . HIS B 1 237 ? 113.461 109.655 116.999 1.00 254.65 ?  237  HIS B CA  1 
ATOM   4515 C C   . HIS B 1 237 ? 112.047 109.863 117.401 1.00 254.65 ?  237  HIS B C   1 
ATOM   4516 O O   . HIS B 1 237 ? 111.271 110.345 116.628 1.00 254.65 ?  237  HIS B O   1 
ATOM   4517 C CB  . HIS B 1 237 ? 113.735 108.165 117.041 1.00 254.65 ?  237  HIS B CB  1 
ATOM   4518 C CG  . HIS B 1 237 ? 113.035 107.436 115.940 1.00 254.65 ?  237  HIS B CG  1 
ATOM   4519 N ND1 . HIS B 1 237 ? 112.666 106.116 116.024 1.00 254.65 ?  237  HIS B ND1 1 
ATOM   4520 C CD2 . HIS B 1 237 ? 112.596 107.869 114.735 1.00 254.65 ?  237  HIS B CD2 1 
ATOM   4521 C CE1 . HIS B 1 237 ? 112.040 105.758 114.920 1.00 254.65 ?  237  HIS B CE1 1 
ATOM   4522 N NE2 . HIS B 1 237 ? 111.987 106.805 114.119 1.00 254.65 ?  237  HIS B NE2 1 
ATOM   4523 N N   . ILE B 1 238 ? 111.724 109.543 118.647 1.00 265.51 ?  238  ILE B N   1 
ATOM   4524 C CA  . ILE B 1 238 ? 110.388 109.797 119.151 1.00 265.51 ?  238  ILE B CA  1 
ATOM   4525 C C   . ILE B 1 238 ? 110.106 111.285 118.942 1.00 265.51 ?  238  ILE B C   1 
ATOM   4526 O O   . ILE B 1 238 ? 109.016 111.640 118.515 1.00 265.51 ?  238  ILE B O   1 
ATOM   4527 C CB  . ILE B 1 238 ? 110.238 109.356 120.628 1.00 265.51 ?  238  ILE B CB  1 
ATOM   4528 C CG1 . ILE B 1 238 ? 109.781 107.906 120.696 1.00 265.51 ?  238  ILE B CG1 1 
ATOM   4529 C CG2 . ILE B 1 238 ? 109.305 110.258 121.424 1.00 265.51 ?  238  ILE B CG2 1 
ATOM   4530 C CD1 . ILE B 1 238 ? 110.420 107.144 121.831 1.00 265.51 ?  238  ILE B CD1 1 
ATOM   4531 N N   . ALA B 1 239 ? 111.100 112.145 119.172 1.00 245.47 ?  239  ALA B N   1 
ATOM   4532 C CA  . ALA B 1 239 ? 110.847 113.559 118.991 1.00 245.47 ?  239  ALA B CA  1 
ATOM   4533 C C   . ALA B 1 239 ? 110.852 113.968 117.541 1.00 245.47 ?  239  ALA B C   1 
ATOM   4534 O O   . ALA B 1 239 ? 110.210 114.937 117.180 1.00 245.47 ?  239  ALA B O   1 
ATOM   4535 C CB  . ALA B 1 239 ? 111.856 114.363 119.759 1.00 245.47 ?  239  ALA B CB  1 
ATOM   4536 N N   . SER B 1 240 ? 111.574 113.239 116.705 1.00 275.90 ?  240  SER B N   1 
ATOM   4537 C CA  . SER B 1 240 ? 111.570 113.523 115.282 1.00 275.90 ?  240  SER B CA  1 
ATOM   4538 C C   . SER B 1 240 ? 110.304 112.981 114.637 1.00 275.90 ?  240  SER B C   1 
ATOM   4539 O O   . SER B 1 240 ? 109.801 113.568 113.688 1.00 275.90 ?  240  SER B O   1 
ATOM   4540 C CB  . SER B 1 240 ? 112.814 112.949 114.629 1.00 275.90 ?  240  SER B CB  1 
ATOM   4541 O OG  . SER B 1 240 ? 113.960 113.698 114.992 1.00 275.90 ?  240  SER B OG  1 
ATOM   4542 N N   . ILE B 1 241 ? 109.769 111.872 115.145 1.00 272.13 ?  241  ILE B N   1 
ATOM   4543 C CA  . ILE B 1 241 ? 108.498 111.379 114.628 1.00 272.13 ?  241  ILE B CA  1 
ATOM   4544 C C   . ILE B 1 241 ? 107.474 112.397 115.048 1.00 272.13 ?  241  ILE B C   1 
ATOM   4545 O O   . ILE B 1 241 ? 106.673 112.847 114.246 1.00 272.13 ?  241  ILE B O   1 
ATOM   4546 C CB  . ILE B 1 241 ? 108.068 110.030 115.224 1.00 272.13 ?  241  ILE B CB  1 
ATOM   4547 C CG1 . ILE B 1 241 ? 109.060 108.930 114.889 1.00 272.13 ?  241  ILE B CG1 1 
ATOM   4548 C CG2 . ILE B 1 241 ? 106.704 109.626 114.695 1.00 272.13 ?  241  ILE B CG2 1 
ATOM   4549 C CD1 . ILE B 1 241 ? 109.117 107.855 115.945 1.00 272.13 ?  241  ILE B CD1 1 
ATOM   4550 N N   . CYS B 1 242 ? 107.522 112.791 116.313 1.00 298.43 ?  242  CYS B N   1 
ATOM   4551 C CA  . CYS B 1 242 ? 106.578 113.770 116.812 1.00 298.43 ?  242  CYS B CA  1 
ATOM   4552 C C   . CYS B 1 242 ? 106.670 115.057 116.025 1.00 298.43 ?  242  CYS B C   1 
ATOM   4553 O O   . CYS B 1 242 ? 105.654 115.642 115.708 1.00 298.43 ?  242  CYS B O   1 
ATOM   4554 C CB  . CYS B 1 242 ? 106.811 114.030 118.290 1.00 298.43 ?  242  CYS B CB  1 
ATOM   4555 S SG  . CYS B 1 242 ? 105.326 113.956 119.310 1.00 298.43 ?  242  CYS B SG  1 
ATOM   4556 N N   . ALA B 1 243 ? 107.877 115.493 115.688 1.00 278.91 ?  243  ALA B N   1 
ATOM   4557 C CA  . ALA B 1 243 ? 108.040 116.689 114.874 1.00 278.91 ?  243  ALA B CA  1 
ATOM   4558 C C   . ALA B 1 243 ? 107.364 116.528 113.532 1.00 278.91 ?  243  ALA B C   1 
ATOM   4559 O O   . ALA B 1 243 ? 106.613 117.394 113.119 1.00 278.91 ?  243  ALA B O   1 
ATOM   4560 C CB  . ALA B 1 243 ? 109.508 117.021 114.694 1.00 278.91 ?  243  ALA B CB  1 
ATOM   4561 N N   . ALA B 1 244 ? 107.617 115.416 112.851 1.00 296.98 ?  244  ALA B N   1 
ATOM   4562 C CA  . ALA B 1 244 ? 106.993 115.162 111.560 1.00 296.98 ?  244  ALA B CA  1 
ATOM   4563 C C   . ALA B 1 244 ? 105.478 115.141 111.664 1.00 296.98 ?  244  ALA B C   1 
ATOM   4564 O O   . ALA B 1 244 ? 104.792 115.756 110.855 1.00 296.98 ?  244  ALA B O   1 
ATOM   4565 C CB  . ALA B 1 244 ? 107.497 113.852 110.990 1.00 296.98 ?  244  ALA B CB  1 
ATOM   4566 N N   . VAL B 1 245 ? 104.952 114.440 112.658 1.00 291.00 ?  245  VAL B N   1 
ATOM   4567 C CA  . VAL B 1 245 ? 103.511 114.365 112.852 1.00 291.00 ?  245  VAL B CA  1 
ATOM   4568 C C   . VAL B 1 245 ? 102.937 115.742 113.153 1.00 291.00 ?  245  VAL B C   1 
ATOM   4569 O O   . VAL B 1 245 ? 101.964 116.153 112.536 1.00 291.00 ?  245  VAL B O   1 
ATOM   4570 C CB  . VAL B 1 245 ? 103.168 113.363 113.970 1.00 291.00 ?  245  VAL B CB  1 
ATOM   4571 C CG1 . VAL B 1 245 ? 101.708 113.463 114.387 1.00 291.00 ?  245  VAL B CG1 1 
ATOM   4572 C CG2 . VAL B 1 245 ? 103.487 111.949 113.514 1.00 291.00 ?  245  VAL B CG2 1 
ATOM   4573 N N   . LEU B 1 246 ? 103.558 116.474 114.073 1.00 301.56 ?  246  LEU B N   1 
ATOM   4574 C CA  . LEU B 1 246 ? 103.088 117.813 114.412 1.00 301.56 ?  246  LEU B CA  1 
ATOM   4575 C C   . LEU B 1 246 ? 103.117 118.713 113.196 1.00 301.56 ?  246  LEU B C   1 
ATOM   4576 O O   . LEU B 1 246 ? 102.188 119.475 112.971 1.00 301.56 ?  246  LEU B O   1 
ATOM   4577 C CB  . LEU B 1 246 ? 103.924 118.426 115.533 1.00 301.56 ?  246  LEU B CB  1 
ATOM   4578 C CG  . LEU B 1 246 ? 103.263 118.486 116.910 1.00 301.56 ?  246  LEU B CG  1 
ATOM   4579 C CD1 . LEU B 1 246 ? 101.923 117.772 116.912 1.00 301.56 ?  246  LEU B CD1 1 
ATOM   4580 C CD2 . LEU B 1 246 ? 104.167 117.900 117.978 1.00 301.56 ?  246  LEU B CD2 1 
ATOM   4581 N N   . SER B 1 247 ? 104.171 118.616 112.396 1.00 308.97 ?  247  SER B N   1 
ATOM   4582 C CA  . SER B 1 247 ? 104.267 119.421 111.187 1.00 308.97 ?  247  SER B CA  1 
ATOM   4583 C C   . SER B 1 247 ? 103.103 119.136 110.255 1.00 308.97 ?  247  SER B C   1 
ATOM   4584 O O   . SER B 1 247 ? 102.503 120.055 109.725 1.00 308.97 ?  247  SER B O   1 
ATOM   4585 C CB  . SER B 1 247 ? 105.598 119.183 110.474 1.00 308.97 ?  247  SER B CB  1 
ATOM   4586 O OG  . SER B 1 247 ? 105.403 118.663 109.172 1.00 308.97 ?  247  SER B OG  1 
ATOM   4587 N N   . LYS B 1 248 ? 102.770 117.865 110.065 1.00 305.64 ?  248  LYS B N   1 
ATOM   4588 C CA  . LYS B 1 248 ? 101.655 117.511 109.199 1.00 305.64 ?  248  LYS B CA  1 
ATOM   4589 C C   . LYS B 1 248 ? 100.354 118.002 109.786 1.00 305.64 ?  248  LYS B C   1 
ATOM   4590 O O   . LYS B 1 248 ? 99.581  118.661 109.104 1.00 305.64 ?  248  LYS B O   1 
ATOM   4591 C CB  . LYS B 1 248 ? 101.599 116.006 108.986 1.00 305.64 ?  248  LYS B CB  1 
ATOM   4592 C CG  . LYS B 1 248 ? 102.685 115.483 108.069 1.00 305.64 ?  248  LYS B CG  1 
ATOM   4593 C CD  . LYS B 1 248 ? 102.369 114.073 107.603 1.00 305.64 ?  248  LYS B CD  1 
ATOM   4594 C CE  . LYS B 1 248 ? 101.620 114.089 106.281 1.00 305.64 ?  248  LYS B CE  1 
ATOM   4595 N NZ  . LYS B 1 248 ? 100.239 113.549 106.414 1.00 305.64 ?  248  LYS B NZ  1 
ATOM   4596 N N   . PHE B 1 249 ? 100.121 117.714 111.060 1.00 306.46 ?  249  PHE B N   1 
ATOM   4597 C CA  . PHE B 1 249 ? 98.898  118.151 111.732 1.00 306.46 ?  249  PHE B CA  1 
ATOM   4598 C C   . PHE B 1 249 ? 98.684  119.654 111.582 1.00 306.46 ?  249  PHE B C   1 
ATOM   4599 O O   . PHE B 1 249 ? 97.560  120.109 111.401 1.00 306.46 ?  249  PHE B O   1 
ATOM   4600 C CB  . PHE B 1 249 ? 98.916  117.680 113.203 1.00 306.46 ?  249  PHE B CB  1 
ATOM   4601 C CG  . PHE B 1 249 ? 98.452  118.706 114.205 1.00 306.46 ?  249  PHE B CG  1 
ATOM   4602 C CD1 . PHE B 1 249 ? 97.106  118.856 114.496 1.00 306.46 ?  249  PHE B CD1 1 
ATOM   4603 C CD2 . PHE B 1 249 ? 99.369  119.488 114.893 1.00 306.46 ?  249  PHE B CD2 1 
ATOM   4604 C CE1 . PHE B 1 249 ? 96.682  119.792 115.419 1.00 306.46 ?  249  PHE B CE1 1 
ATOM   4605 C CE2 . PHE B 1 249 ? 98.952  120.422 115.818 1.00 306.46 ?  249  PHE B CE2 1 
ATOM   4606 C CZ  . PHE B 1 249 ? 97.606  120.573 116.084 1.00 306.46 ?  249  PHE B CZ  1 
ATOM   4607 N N   . MET B 1 250 ? 99.757  120.427 111.641 1.00 308.01 ?  250  MET B N   1 
ATOM   4608 C CA  . MET B 1 250 ? 99.639  121.862 111.501 1.00 308.01 ?  250  MET B CA  1 
ATOM   4609 C C   . MET B 1 250 ? 99.582  122.277 110.046 1.00 308.01 ?  250  MET B C   1 
ATOM   4610 O O   . MET B 1 250 ? 98.536  122.700 109.561 1.00 308.01 ?  250  MET B O   1 
ATOM   4611 C CB  . MET B 1 250 ? 100.820 122.546 112.179 1.00 308.01 ?  250  MET B CB  1 
ATOM   4612 C CG  . MET B 1 250 ? 100.418 123.596 113.192 1.00 308.01 ?  250  MET B CG  1 
ATOM   4613 S SD  . MET B 1 250 ? 101.785 123.964 114.296 1.00 308.01 ?  250  MET B SD  1 
ATOM   4614 C CE  . MET B 1 250 ? 102.086 122.344 114.990 1.00 308.01 ?  250  MET B CE  1 
ATOM   4615 N N   . SER B 1 251 ? 100.699 122.158 109.343 1.00 303.41 ?  251  SER B N   1 
ATOM   4616 C CA  . SER B 1 251 ? 100.765 122.608 107.954 1.00 303.41 ?  251  SER B CA  1 
ATOM   4617 C C   . SER B 1 251 ? 99.827  121.901 106.991 1.00 303.41 ?  251  SER B C   1 
ATOM   4618 O O   . SER B 1 251 ? 98.956  122.538 106.399 1.00 303.41 ?  251  SER B O   1 
ATOM   4619 C CB  . SER B 1 251 ? 102.204 122.512 107.437 1.00 303.41 ?  251  SER B CB  1 
ATOM   4620 O OG  . SER B 1 251 ? 102.234 122.394 106.025 1.00 303.41 ?  251  SER B OG  1 
ATOM   4621 N N   . VAL B 1 252 ? 99.990  120.594 106.817 1.00 294.29 ?  252  VAL B N   1 
ATOM   4622 C CA  . VAL B 1 252 ? 99.176  119.895 105.817 1.00 294.29 ?  252  VAL B CA  1 
ATOM   4623 C C   . VAL B 1 252 ? 97.716  119.691 106.235 1.00 294.29 ?  252  VAL B C   1 
ATOM   4624 O O   . VAL B 1 252 ? 96.841  119.552 105.380 1.00 294.29 ?  252  VAL B O   1 
ATOM   4625 C CB  . VAL B 1 252 ? 99.870  118.609 105.291 1.00 294.29 ?  252  VAL B CB  1 
ATOM   4626 C CG1 . VAL B 1 252 ? 101.375 118.699 105.489 1.00 294.29 ?  252  VAL B CG1 1 
ATOM   4627 C CG2 . VAL B 1 252 ? 99.315  117.346 105.922 1.00 294.29 ?  252  VAL B CG2 1 
ATOM   4628 N N   . PHE B 1 253 ? 97.437  119.715 107.533 1.00 291.46 ?  253  PHE B N   1 
ATOM   4629 C CA  . PHE B 1 253 ? 96.055  119.607 107.989 1.00 291.46 ?  253  PHE B CA  1 
ATOM   4630 C C   . PHE B 1 253 ? 95.633  120.914 108.647 1.00 291.46 ?  253  PHE B C   1 
ATOM   4631 O O   . PHE B 1 253 ? 95.072  120.918 109.741 1.00 291.46 ?  253  PHE B O   1 
ATOM   4632 C CB  . PHE B 1 253 ? 95.877  118.438 108.960 1.00 291.46 ?  253  PHE B CB  1 
ATOM   4633 C CG  . PHE B 1 253 ? 96.238  117.103 108.379 1.00 291.46 ?  253  PHE B CG  1 
ATOM   4634 C CD1 . PHE B 1 253 ? 95.651  116.660 107.207 1.00 291.46 ?  253  PHE B CD1 1 
ATOM   4635 C CD2 . PHE B 1 253 ? 97.156  116.284 109.012 1.00 291.46 ?  253  PHE B CD2 1 
ATOM   4636 C CE1 . PHE B 1 253 ? 95.982  115.430 106.671 1.00 291.46 ?  253  PHE B CE1 1 
ATOM   4637 C CE2 . PHE B 1 253 ? 97.494  115.056 108.484 1.00 291.46 ?  253  PHE B CE2 1 
ATOM   4638 C CZ  . PHE B 1 253 ? 96.904  114.627 107.312 1.00 291.46 ?  253  PHE B CZ  1 
ATOM   4639 N N   . TYR B 1 262 ? 112.107 123.284 106.139 1.00 316.42 ?  262  TYR B N   1 
ATOM   4640 C CA  . TYR B 1 262 ? 112.080 122.006 105.436 1.00 316.42 ?  262  TYR B CA  1 
ATOM   4641 C C   . TYR B 1 262 ? 112.242 120.845 106.404 1.00 316.42 ?  262  TYR B C   1 
ATOM   4642 O O   . TYR B 1 262 ? 112.249 121.043 107.614 1.00 316.42 ?  262  TYR B O   1 
ATOM   4643 C CB  . TYR B 1 262 ? 113.148 121.951 104.335 1.00 316.42 ?  262  TYR B CB  1 
ATOM   4644 C CG  . TYR B 1 262 ? 114.433 122.694 104.636 1.00 316.42 ?  262  TYR B CG  1 
ATOM   4645 C CD1 . TYR B 1 262 ? 115.481 122.066 105.287 1.00 316.42 ?  262  TYR B CD1 1 
ATOM   4646 C CD2 . TYR B 1 262 ? 114.610 124.016 104.236 1.00 316.42 ?  262  TYR B CD2 1 
ATOM   4647 C CE1 . TYR B 1 262 ? 116.660 122.732 105.552 1.00 316.42 ?  262  TYR B CE1 1 
ATOM   4648 C CE2 . TYR B 1 262 ? 115.783 124.692 104.505 1.00 316.42 ?  262  TYR B CE2 1 
ATOM   4649 C CZ  . TYR B 1 262 ? 116.805 124.045 105.162 1.00 316.42 ?  262  TYR B CZ  1 
ATOM   4650 O OH  . TYR B 1 262 ? 117.978 124.708 105.431 1.00 316.42 ?  262  TYR B OH  1 
ATOM   4651 N N   . TYR B 1 263 ? 112.385 119.633 105.879 1.00 309.96 ?  263  TYR B N   1 
ATOM   4652 C CA  . TYR B 1 263 ? 112.486 118.460 106.741 1.00 309.96 ?  263  TYR B CA  1 
ATOM   4653 C C   . TYR B 1 263 ? 113.670 118.515 107.685 1.00 309.96 ?  263  TYR B C   1 
ATOM   4654 O O   . TYR B 1 263 ? 113.532 118.211 108.861 1.00 309.96 ?  263  TYR B O   1 
ATOM   4655 C CB  . TYR B 1 263 ? 112.552 117.177 105.919 1.00 309.96 ?  263  TYR B CB  1 
ATOM   4656 C CG  . TYR B 1 263 ? 111.618 116.101 106.419 1.00 309.96 ?  263  TYR B CG  1 
ATOM   4657 C CD1 . TYR B 1 263 ? 110.597 116.404 107.312 1.00 309.96 ?  263  TYR B CD1 1 
ATOM   4658 C CD2 . TYR B 1 263 ? 111.753 114.784 106.000 1.00 309.96 ?  263  TYR B CD2 1 
ATOM   4659 C CE1 . TYR B 1 263 ? 109.739 115.426 107.774 1.00 309.96 ?  263  TYR B CE1 1 
ATOM   4660 C CE2 . TYR B 1 263 ? 110.898 113.800 106.455 1.00 309.96 ?  263  TYR B CE2 1 
ATOM   4661 C CZ  . TYR B 1 263 ? 109.894 114.127 107.341 1.00 309.96 ?  263  TYR B CZ  1 
ATOM   4662 O OH  . TYR B 1 263 ? 109.039 113.151 107.794 1.00 309.96 ?  263  TYR B OH  1 
ATOM   4663 N N   . SER B 1 264 ? 114.834 118.896 107.174 1.00 293.58 ?  264  SER B N   1 
ATOM   4664 C CA  . SER B 1 264 ? 116.011 119.002 108.020 1.00 293.58 ?  264  SER B CA  1 
ATOM   4665 C C   . SER B 1 264 ? 115.758 119.927 109.192 1.00 293.58 ?  264  SER B C   1 
ATOM   4666 O O   . SER B 1 264 ? 116.052 119.570 110.318 1.00 293.58 ?  264  SER B O   1 
ATOM   4667 C CB  . SER B 1 264 ? 117.227 119.472 107.228 1.00 293.58 ?  264  SER B CB  1 
ATOM   4668 O OG  . SER B 1 264 ? 118.076 118.388 106.898 1.00 293.58 ?  264  SER B OG  1 
ATOM   4669 N N   . ASP B 1 265 ? 115.201 121.105 108.934 1.00 302.56 ?  265  ASP B N   1 
ATOM   4670 C CA  . ASP B 1 265 ? 114.895 122.049 110.001 1.00 302.56 ?  265  ASP B CA  1 
ATOM   4671 C C   . ASP B 1 265 ? 114.008 121.412 111.038 1.00 302.56 ?  265  ASP B C   1 
ATOM   4672 O O   . ASP B 1 265 ? 114.328 121.429 112.223 1.00 302.56 ?  265  ASP B O   1 
ATOM   4673 C CB  . ASP B 1 265 ? 114.184 123.272 109.431 1.00 302.56 ?  265  ASP B CB  1 
ATOM   4674 C CG  . ASP B 1 265 ? 115.089 124.125 108.582 1.00 302.56 ?  265  ASP B CG  1 
ATOM   4675 O OD1 . ASP B 1 265 ? 116.313 123.892 108.612 1.00 302.56 ?  265  ASP B OD1 1 
ATOM   4676 O OD2 . ASP B 1 265 ? 114.581 125.026 107.886 1.00 302.56 ?  265  ASP B OD2 1 
ATOM   4677 N N   . ILE B 1 266 ? 112.891 120.845 110.598 1.00 288.36 ?  266  ILE B N   1 
ATOM   4678 C CA  . ILE B 1 266 ? 111.945 120.207 111.508 1.00 288.36 ?  266  ILE B CA  1 
ATOM   4679 C C   . ILE B 1 266 ? 112.597 119.118 112.356 1.00 288.36 ?  266  ILE B C   1 
ATOM   4680 O O   . ILE B 1 266 ? 112.424 119.090 113.573 1.00 288.36 ?  266  ILE B O   1 
ATOM   4681 C CB  . ILE B 1 266 ? 110.740 119.674 110.693 1.00 288.36 ?  266  ILE B CB  1 
ATOM   4682 C CG1 . ILE B 1 266 ? 109.793 120.824 110.355 1.00 288.36 ?  266  ILE B CG1 1 
ATOM   4683 C CG2 . ILE B 1 266 ? 109.978 118.577 111.410 1.00 288.36 ?  266  ILE B CG2 1 
ATOM   4684 C CD1 . ILE B 1 266 ? 109.044 120.630 109.057 1.00 288.36 ?  266  ILE B CD1 1 
ATOM   4685 N N   . LEU B 1 267 ? 113.381 118.253 111.732 1.00 268.67 ?  267  LEU B N   1 
ATOM   4686 C CA  . LEU B 1 267 ? 114.001 117.152 112.457 1.00 268.67 ?  267  LEU B CA  1 
ATOM   4687 C C   . LEU B 1 267 ? 115.195 117.577 113.297 1.00 268.67 ?  267  LEU B C   1 
ATOM   4688 O O   . LEU B 1 267 ? 115.551 116.888 114.243 1.00 268.67 ?  267  LEU B O   1 
ATOM   4689 C CB  . LEU B 1 267 ? 114.409 116.054 111.485 1.00 268.67 ?  267  LEU B CB  1 
ATOM   4690 C CG  . LEU B 1 267 ? 113.496 114.833 111.429 1.00 268.67 ?  267  LEU B CG  1 
ATOM   4691 C CD1 . LEU B 1 267 ? 112.126 115.176 110.864 1.00 268.67 ?  267  LEU B CD1 1 
ATOM   4692 C CD2 . LEU B 1 267 ? 114.162 113.747 110.608 1.00 268.67 ?  267  LEU B CD2 1 
ATOM   4693 N N   . THR B 1 268 ? 115.820 118.699 112.960 1.00 265.95 ?  268  THR B N   1 
ATOM   4694 C CA  . THR B 1 268 ? 116.933 119.208 113.756 1.00 265.95 ?  268  THR B CA  1 
ATOM   4695 C C   . THR B 1 268 ? 116.381 119.727 115.066 1.00 265.95 ?  268  THR B C   1 
ATOM   4696 O O   . THR B 1 268 ? 116.961 119.507 116.127 1.00 265.95 ?  268  THR B O   1 
ATOM   4697 C CB  . THR B 1 268 ? 117.685 120.333 113.018 1.00 30.00  ?  268  THR B CB  1 
ATOM   4698 O OG1 . THR B 1 268 ? 118.320 119.797 111.852 1.00 30.00  ?  268  THR B OG1 1 
ATOM   4699 C CG2 . THR B 1 268 ? 118.743 120.967 113.907 1.00 30.00  ?  268  THR B CG2 1 
ATOM   4700 N N   . VAL B 1 269 ? 115.248 120.414 115.002 1.00 271.98 ?  269  VAL B N   1 
ATOM   4701 C CA  . VAL B 1 269 ? 114.612 120.889 116.220 1.00 271.98 ?  269  VAL B CA  1 
ATOM   4702 C C   . VAL B 1 269 ? 114.075 119.688 116.975 1.00 271.98 ?  269  VAL B C   1 
ATOM   4703 O O   . VAL B 1 269 ? 114.132 119.649 118.199 1.00 271.98 ?  269  VAL B O   1 
ATOM   4704 C CB  . VAL B 1 269 ? 113.499 121.902 115.912 1.00 271.98 ?  269  VAL B CB  1 
ATOM   4705 C CG1 . VAL B 1 269 ? 112.802 122.338 117.188 1.00 271.98 ?  269  VAL B CG1 1 
ATOM   4706 C CG2 . VAL B 1 269 ? 114.094 123.109 115.210 1.00 271.98 ?  269  VAL B CG2 1 
ATOM   4707 N N   . GLY B 1 270 ? 113.580 118.688 116.250 1.00 274.45 ?  270  GLY B N   1 
ATOM   4708 C CA  . GLY B 1 270 ? 113.113 117.477 116.903 1.00 274.45 ?  270  GLY B CA  1 
ATOM   4709 C C   . GLY B 1 270 ? 114.261 116.872 117.680 1.00 274.45 ?  270  GLY B C   1 
ATOM   4710 O O   . GLY B 1 270 ? 114.082 116.418 118.800 1.00 274.45 ?  270  GLY B O   1 
ATOM   4711 N N   . CYS B 1 271 ? 115.457 116.882 117.106 1.00 276.29 ?  271  CYS B N   1 
ATOM   4712 C CA  . CYS B 1 271 ? 116.624 116.378 117.818 1.00 276.29 ?  271  CYS B CA  1 
ATOM   4713 C C   . CYS B 1 271 ? 116.877 117.166 119.085 1.00 276.29 ?  271  CYS B C   1 
ATOM   4714 O O   . CYS B 1 271 ? 117.091 116.586 120.143 1.00 276.29 ?  271  CYS B O   1 
ATOM   4715 C CB  . CYS B 1 271 ? 117.871 116.412 116.931 1.00 276.29 ?  271  CYS B CB  1 
ATOM   4716 S SG  . CYS B 1 271 ? 117.922 115.201 115.589 1.00 276.29 ?  271  CYS B SG  1 
ATOM   4717 N N   . ALA B 1 272 ? 116.844 118.489 118.987 1.00 296.18 ?  272  ALA B N   1 
ATOM   4718 C CA  . ALA B 1 272 ? 117.084 119.340 120.145 1.00 296.18 ?  272  ALA B CA  1 
ATOM   4719 C C   . ALA B 1 272 ? 116.124 119.042 121.268 1.00 296.18 ?  272  ALA B C   1 
ATOM   4720 O O   . ALA B 1 272 ? 116.539 118.880 122.409 1.00 296.18 ?  272  ALA B O   1 
ATOM   4721 C CB  . ALA B 1 272 ? 116.980 120.798 119.749 1.00 296.18 ?  272  ALA B CB  1 
ATOM   4722 N N   . VAL B 1 273 ? 114.837 118.966 120.952 1.00 306.83 ?  273  VAL B N   1 
ATOM   4723 C CA  . VAL B 1 273 ? 113.840 118.734 121.987 1.00 306.83 ?  273  VAL B CA  1 
ATOM   4724 C C   . VAL B 1 273 ? 113.859 117.300 122.479 1.00 306.83 ?  273  VAL B C   1 
ATOM   4725 O O   . VAL B 1 273 ? 113.499 117.042 123.611 1.00 306.83 ?  273  VAL B O   1 
ATOM   4726 C CB  . VAL B 1 273 ? 112.429 119.158 121.544 1.00 306.83 ?  273  VAL B CB  1 
ATOM   4727 C CG1 . VAL B 1 273 ? 112.476 120.559 120.984 1.00 306.83 ?  273  VAL B CG1 1 
ATOM   4728 C CG2 . VAL B 1 273 ? 111.868 118.205 120.509 1.00 306.83 ?  273  VAL B CG2 1 
ATOM   4729 N N   . GLY B 1 274 ? 114.303 116.366 121.649 1.00 284.31 ?  274  GLY B N   1 
ATOM   4730 C CA  . GLY B 1 274 ? 114.418 114.993 122.088 1.00 284.31 ?  274  GLY B CA  1 
ATOM   4731 C C   . GLY B 1 274 ? 115.435 114.914 123.190 1.00 284.31 ?  274  GLY B C   1 
ATOM   4732 O O   . GLY B 1 274 ? 115.141 114.436 124.283 1.00 284.31 ?  274  GLY B O   1 
ATOM   4733 N N   . VAL B 1 275 ? 116.636 115.405 122.918 1.00 263.92 ?  275  VAL B N   1 
ATOM   4734 C CA  . VAL B 1 275 ? 117.678 115.392 123.929 1.00 263.92 ?  275  VAL B CA  1 
ATOM   4735 C C   . VAL B 1 275 ? 117.273 116.265 125.106 1.00 263.92 ?  275  VAL B C   1 
ATOM   4736 O O   . VAL B 1 275 ? 117.400 115.856 126.252 1.00 263.92 ?  275  VAL B O   1 
ATOM   4737 C CB  . VAL B 1 275 ? 119.032 115.844 123.359 1.00 263.92 ?  275  VAL B CB  1 
ATOM   4738 C CG1 . VAL B 1 275 ? 120.143 115.551 124.352 1.00 263.92 ?  275  VAL B CG1 1 
ATOM   4739 C CG2 . VAL B 1 275 ? 119.313 115.136 122.044 1.00 263.92 ?  275  VAL B CG2 1 
ATOM   4740 N N   . GLY B 1 276 ? 116.748 117.450 124.828 1.00 285.28 ?  276  GLY B N   1 
ATOM   4741 C CA  . GLY B 1 276 ? 116.330 118.345 125.889 1.00 285.28 ?  276  GLY B CA  1 
ATOM   4742 C C   . GLY B 1 276 ? 115.293 117.764 126.823 1.00 285.28 ?  276  GLY B C   1 
ATOM   4743 O O   . GLY B 1 276 ? 115.420 117.893 128.036 1.00 285.28 ?  276  GLY B O   1 
ATOM   4744 N N   . CYS B 1 277 ? 114.269 117.118 126.277 1.00 314.53 ?  277  CYS B N   1 
ATOM   4745 C CA  . CYS B 1 277 ? 113.188 116.597 127.110 1.00 314.53 ?  277  CYS B CA  1 
ATOM   4746 C C   . CYS B 1 277 ? 113.540 115.290 127.795 1.00 314.53 ?  277  CYS B C   1 
ATOM   4747 O O   . CYS B 1 277 ? 112.911 114.928 128.781 1.00 314.53 ?  277  CYS B O   1 
ATOM   4748 C CB  . CYS B 1 277 ? 111.907 116.429 126.292 1.00 314.53 ?  277  CYS B CB  1 
ATOM   4749 S SG  . CYS B 1 277 ? 111.796 114.854 125.417 1.00 314.53 ?  277  CYS B SG  1 
ATOM   4750 N N   . CYS B 1 278 ? 114.531 114.579 127.279 1.00 274.97 ?  278  CYS B N   1 
ATOM   4751 C CA  . CYS B 1 278 ? 114.952 113.321 127.877 1.00 274.97 ?  278  CYS B CA  1 
ATOM   4752 C C   . CYS B 1 278 ? 115.241 113.495 129.347 1.00 274.97 ?  278  CYS B C   1 
ATOM   4753 O O   . CYS B 1 278 ? 114.484 113.035 130.202 1.00 274.97 ?  278  CYS B O   1 
ATOM   4754 C CB  . CYS B 1 278 ? 116.235 112.867 127.196 1.00 274.97 ?  278  CYS B CB  1 
ATOM   4755 S SG  . CYS B 1 278 ? 116.384 111.095 126.973 1.00 274.97 ?  278  CYS B SG  1 
ATOM   4756 N N   . PHE B 1 279 ? 116.356 114.153 129.646 1.00 227.42 ?  279  PHE B N   1 
ATOM   4757 C CA  . PHE B 1 279 ? 116.781 114.341 131.035 1.00 227.42 ?  279  PHE B CA  1 
ATOM   4758 C C   . PHE B 1 279 ? 116.496 115.689 131.646 1.00 227.42 ?  279  PHE B C   1 
ATOM   4759 O O   . PHE B 1 279 ? 116.716 115.875 132.839 1.00 227.42 ?  279  PHE B O   1 
ATOM   4760 C CB  . PHE B 1 279 ? 118.293 114.124 131.177 1.00 227.42 ?  279  PHE B CB  1 
ATOM   4761 C CG  . PHE B 1 279 ? 119.098 114.581 129.995 1.00 227.42 ?  279  PHE B CG  1 
ATOM   4762 C CD1 . PHE B 1 279 ? 118.781 115.731 129.294 1.00 227.42 ?  279  PHE B CD1 1 
ATOM   4763 C CD2 . PHE B 1 279 ? 120.203 113.870 129.610 1.00 227.42 ?  279  PHE B CD2 1 
ATOM   4764 C CE1 . PHE B 1 279 ? 119.523 116.126 128.210 1.00 227.42 ?  279  PHE B CE1 1 
ATOM   4765 C CE2 . PHE B 1 279 ? 120.940 114.249 128.511 1.00 227.42 ?  279  PHE B CE2 1 
ATOM   4766 C CZ  . PHE B 1 279 ? 120.599 115.382 127.812 1.00 227.42 ?  279  PHE B CZ  1 
ATOM   4767 N N   . GLY B 1 280 ? 116.039 116.645 130.855 1.00 219.72 ?  280  GLY B N   1 
ATOM   4768 C CA  . GLY B 1 280 ? 115.889 117.974 131.435 1.00 219.72 ?  280  GLY B CA  1 
ATOM   4769 C C   . GLY B 1 280 ? 117.150 118.791 131.255 1.00 219.72 ?  280  GLY B C   1 
ATOM   4770 O O   . GLY B 1 280 ? 117.733 119.230 132.246 1.00 219.72 ?  280  GLY B O   1 
ATOM   4771 N N   . THR B 1 281 ? 117.565 119.012 130.018 1.00 234.03 ?  281  THR B N   1 
ATOM   4772 C CA  . THR B 1 281 ? 118.789 119.743 129.672 1.00 234.03 ?  281  THR B CA  1 
ATOM   4773 C C   . THR B 1 281 ? 118.487 120.578 128.367 1.00 234.03 ?  281  THR B C   1 
ATOM   4774 O O   . THR B 1 281 ? 118.824 120.128 127.283 1.00 234.03 ?  281  THR B O   1 
ATOM   4775 C CB  . THR B 1 281 ? 120.118 119.015 129.776 1.00 234.03 ?  281  THR B CB  1 
ATOM   4776 O OG1 . THR B 1 281 ? 120.355 118.670 131.148 1.00 234.03 ?  281  THR B OG1 1 
ATOM   4777 C CG2 . THR B 1 281 ? 121.210 119.873 129.342 1.00 234.03 ?  281  THR B CG2 1 
ATOM   4778 N N   . PRO B 1 282 ? 117.776 121.762 128.466 1.00 231.49 ?  282  PRO B N   1 
ATOM   4779 C CA  . PRO B 1 282 ? 117.488 122.615 127.309 1.00 231.49 ?  282  PRO B CA  1 
ATOM   4780 C C   . PRO B 1 282 ? 118.752 122.957 126.520 1.00 231.49 ?  282  PRO B C   1 
ATOM   4781 O O   . PRO B 1 282 ? 118.889 122.465 125.415 1.00 231.49 ?  282  PRO B O   1 
ATOM   4782 C CB  . PRO B 1 282 ? 116.909 123.873 127.945 1.00 231.49 ?  282  PRO B CB  1 
ATOM   4783 C CG  . PRO B 1 282 ? 116.334 123.412 129.237 1.00 231.49 ?  282  PRO B CG  1 
ATOM   4784 C CD  . PRO B 1 282 ? 117.226 122.306 129.717 1.00 231.49 ?  282  PRO B CD  1 
ATOM   4785 N N   . LEU B 1 283 ? 119.655 123.763 127.075 1.00 229.79 ?  283  LEU B N   1 
ATOM   4786 C CA  . LEU B 1 283 ? 120.886 124.156 126.396 1.00 229.79 ?  283  LEU B CA  1 
ATOM   4787 C C   . LEU B 1 283 ? 121.691 122.961 125.925 1.00 229.79 ?  283  LEU B C   1 
ATOM   4788 O O   . LEU B 1 283 ? 121.983 122.850 124.739 1.00 229.79 ?  283  LEU B O   1 
ATOM   4789 C CB  . LEU B 1 283 ? 121.752 125.022 127.307 1.00 229.79 ?  283  LEU B CB  1 
ATOM   4790 C CG  . LEU B 1 283 ? 122.504 126.214 126.717 1.00 229.79 ?  283  LEU B CG  1 
ATOM   4791 C CD1 . LEU B 1 283 ? 122.796 127.227 127.811 1.00 229.79 ?  283  LEU B CD1 1 
ATOM   4792 C CD2 . LEU B 1 283 ? 123.785 125.816 125.999 1.00 229.79 ?  283  LEU B CD2 1 
ATOM   4793 N N   . GLY B 1 284 ? 122.076 122.088 126.853 1.00 243.51 ?  284  GLY B N   1 
ATOM   4794 C CA  . GLY B 1 284 ? 122.858 120.927 126.485 1.00 243.51 ?  284  GLY B CA  1 
ATOM   4795 C C   . GLY B 1 284 ? 122.211 120.127 125.387 1.00 243.51 ?  284  GLY B C   1 
ATOM   4796 O O   . GLY B 1 284 ? 122.902 119.662 124.504 1.00 243.51 ?  284  GLY B O   1 
ATOM   4797 N N   . GLY B 1 285 ? 120.894 119.962 125.433 1.00 256.46 ?  285  GLY B N   1 
ATOM   4798 C CA  . GLY B 1 285 ? 120.181 119.262 124.384 1.00 256.46 ?  285  GLY B CA  1 
ATOM   4799 C C   . GLY B 1 285 ? 120.281 119.882 123.012 1.00 256.46 ?  285  GLY B C   1 
ATOM   4800 O O   . GLY B 1 285 ? 120.538 119.192 122.040 1.00 256.46 ?  285  GLY B O   1 
ATOM   4801 N N   . VAL B 1 286 ? 120.080 121.187 122.915 1.00 248.56 ?  286  VAL B N   1 
ATOM   4802 C CA  . VAL B 1 286 ? 120.237 121.859 121.632 1.00 248.56 ?  286  VAL B CA  1 
ATOM   4803 C C   . VAL B 1 286 ? 121.663 121.696 121.146 1.00 248.56 ?  286  VAL B C   1 
ATOM   4804 O O   . VAL B 1 286 ? 121.887 121.283 120.022 1.00 248.56 ?  286  VAL B O   1 
ATOM   4805 C CB  . VAL B 1 286 ? 119.872 123.356 121.709 1.00 248.56 ?  286  VAL B CB  1 
ATOM   4806 C CG1 . VAL B 1 286 ? 119.668 123.923 120.316 1.00 248.56 ?  286  VAL B CG1 1 
ATOM   4807 C CG2 . VAL B 1 286 ? 118.602 123.545 122.511 1.00 248.56 ?  286  VAL B CG2 1 
ATOM   4808 N N   . LEU B 1 287 ? 122.632 121.989 122.001 1.00 238.93 ?  287  LEU B N   1 
ATOM   4809 C CA  . LEU B 1 287 ? 124.035 121.847 121.633 1.00 238.93 ?  287  LEU B CA  1 
ATOM   4810 C C   . LEU B 1 287 ? 124.337 120.435 121.166 1.00 238.93 ?  287  LEU B C   1 
ATOM   4811 O O   . LEU B 1 287 ? 125.005 120.250 120.153 1.00 238.93 ?  287  LEU B O   1 
ATOM   4812 C CB  . LEU B 1 287 ? 124.907 122.195 122.831 1.00 238.93 ?  287  LEU B CB  1 
ATOM   4813 C CG  . LEU B 1 287 ? 125.539 123.583 122.915 1.00 238.93 ?  287  LEU B CG  1 
ATOM   4814 C CD1 . LEU B 1 287 ? 127.048 123.476 122.769 1.00 238.93 ?  287  LEU B CD1 1 
ATOM   4815 C CD2 . LEU B 1 287 ? 124.964 124.533 121.877 1.00 238.93 ?  287  LEU B CD2 1 
ATOM   4816 N N   . PHE B 1 288 ? 123.848 119.437 121.898 1.00 237.90 ?  288  PHE B N   1 
ATOM   4817 C CA  . PHE B 1 288 ? 124.041 118.044 121.518 1.00 237.90 ?  288  PHE B CA  1 
ATOM   4818 C C   . PHE B 1 288 ? 123.538 117.821 120.120 1.00 237.90 ?  288  PHE B C   1 
ATOM   4819 O O   . PHE B 1 288 ? 124.269 117.317 119.293 1.00 237.90 ?  288  PHE B O   1 
ATOM   4820 C CB  . PHE B 1 288 ? 123.282 117.139 122.477 1.00 237.90 ?  288  PHE B CB  1 
ATOM   4821 C CG  . PHE B 1 288 ? 123.816 115.742 122.559 1.00 237.90 ?  288  PHE B CG  1 
ATOM   4822 C CD1 . PHE B 1 288 ? 125.116 115.505 122.958 1.00 237.90 ?  288  PHE B CD1 1 
ATOM   4823 C CD2 . PHE B 1 288 ? 123.004 114.663 122.259 1.00 237.90 ?  288  PHE B CD2 1 
ATOM   4824 C CE1 . PHE B 1 288 ? 125.600 114.217 123.044 1.00 237.90 ?  288  PHE B CE1 1 
ATOM   4825 C CE2 . PHE B 1 288 ? 123.482 113.372 122.346 1.00 237.90 ?  288  PHE B CE2 1 
ATOM   4826 C CZ  . PHE B 1 288 ? 124.784 113.150 122.737 1.00 237.90 ?  288  PHE B CZ  1 
ATOM   4827 N N   . SER B 1 289 ? 122.299 118.205 119.850 1.00 247.17 ?  289  SER B N   1 
ATOM   4828 C CA  . SER B 1 289 ? 121.725 118.062 118.520 1.00 247.17 ?  289  SER B CA  1 
ATOM   4829 C C   . SER B 1 289 ? 122.616 118.621 117.443 1.00 247.17 ?  289  SER B C   1 
ATOM   4830 O O   . SER B 1 289 ? 122.938 117.926 116.489 1.00 247.17 ?  289  SER B O   1 
ATOM   4831 C CB  . SER B 1 289 ? 120.392 118.790 118.458 1.00 247.17 ?  289  SER B CB  1 
ATOM   4832 O OG  . SER B 1 289 ? 120.049 119.129 117.125 1.00 247.17 ?  289  SER B OG  1 
ATOM   4833 N N   . ILE B 1 290 ? 122.978 119.890 117.566 1.00 266.47 ?  290  ILE B N   1 
ATOM   4834 C CA  . ILE B 1 290 ? 123.839 120.532 116.584 1.00 266.47 ?  290  ILE B CA  1 
ATOM   4835 C C   . ILE B 1 290 ? 125.013 119.642 116.242 1.00 266.47 ?  290  ILE B C   1 
ATOM   4836 O O   . ILE B 1 290 ? 125.336 119.456 115.069 1.00 266.47 ?  290  ILE B O   1 
ATOM   4837 C CB  . ILE B 1 290 ? 124.375 121.857 117.153 1.00 266.47 ?  290  ILE B CB  1 
ATOM   4838 C CG1 . ILE B 1 290 ? 123.283 122.925 117.133 1.00 266.47 ?  290  ILE B CG1 1 
ATOM   4839 C CG2 . ILE B 1 290 ? 125.620 122.324 116.415 1.00 266.47 ?  290  ILE B CG2 1 
ATOM   4840 C CD1 . ILE B 1 290 ? 123.506 124.019 118.149 1.00 266.47 ?  290  ILE B CD1 1 
ATOM   4841 N N   . GLU B 1 291 ? 125.635 119.060 117.257 1.00 258.40 ?  291  GLU B N   1 
ATOM   4842 C CA  . GLU B 1 291 ? 126.824 118.255 117.026 1.00 258.40 ?  291  GLU B CA  1 
ATOM   4843 C C   . GLU B 1 291 ? 126.542 116.850 116.542 1.00 258.40 ?  291  GLU B C   1 
ATOM   4844 O O   . GLU B 1 291 ? 127.129 116.413 115.556 1.00 258.40 ?  291  GLU B O   1 
ATOM   4845 C CB  . GLU B 1 291 ? 127.670 118.211 118.296 1.00 258.40 ?  291  GLU B CB  1 
ATOM   4846 C CG  . GLU B 1 291 ? 128.389 119.516 118.593 1.00 258.40 ?  291  GLU B CG  1 
ATOM   4847 C CD  . GLU B 1 291 ? 128.562 119.767 120.075 1.00 258.40 ?  291  GLU B CD  1 
ATOM   4848 O OE1 . GLU B 1 291 ? 128.051 120.791 120.571 1.00 258.40 ?  291  GLU B OE1 1 
ATOM   4849 O OE2 . GLU B 1 291 ? 129.215 118.945 120.745 1.00 258.40 ?  291  GLU B OE2 1 
ATOM   4850 N N   . VAL B 1 292 ? 125.646 116.134 117.211 1.00 252.65 ?  292  VAL B N   1 
ATOM   4851 C CA  . VAL B 1 292 ? 125.411 114.733 116.853 1.00 252.65 ?  292  VAL B CA  1 
ATOM   4852 C C   . VAL B 1 292 ? 124.860 114.507 115.459 1.00 252.65 ?  292  VAL B C   1 
ATOM   4853 O O   . VAL B 1 292 ? 125.093 113.460 114.880 1.00 252.65 ?  292  VAL B O   1 
ATOM   4854 C CB  . VAL B 1 292 ? 124.528 113.979 117.872 1.00 252.65 ?  292  VAL B CB  1 
ATOM   4855 C CG1 . VAL B 1 292 ? 125.221 113.899 119.215 1.00 252.65 ?  292  VAL B CG1 1 
ATOM   4856 C CG2 . VAL B 1 292 ? 123.144 114.595 117.987 1.00 252.65 ?  292  VAL B CG2 1 
ATOM   4857 N N   . THR B 1 293 ? 124.127 115.469 114.918 1.00 257.68 ?  293  THR B N   1 
ATOM   4858 C CA  . THR B 1 293 ? 123.519 115.260 113.618 1.00 257.68 ?  293  THR B CA  1 
ATOM   4859 C C   . THR B 1 293 ? 124.202 116.062 112.531 1.00 257.68 ?  293  THR B C   1 
ATOM   4860 O O   . THR B 1 293 ? 125.014 115.527 111.784 1.00 257.68 ?  293  THR B O   1 
ATOM   4861 C CB  . THR B 1 293 ? 122.012 115.571 113.631 1.00 257.68 ?  293  THR B CB  1 
ATOM   4862 O OG1 . THR B 1 293 ? 121.756 116.715 114.452 1.00 257.68 ?  293  THR B OG1 1 
ATOM   4863 C CG2 . THR B 1 293 ? 121.232 114.382 114.167 1.00 257.68 ?  293  THR B CG2 1 
ATOM   4864 N N   . SER B 1 294 ? 123.897 117.347 112.448 1.00 249.50 ?  294  SER B N   1 
ATOM   4865 C CA  . SER B 1 294 ? 124.452 118.175 111.386 1.00 249.50 ?  294  SER B CA  1 
ATOM   4866 C C   . SER B 1 294 ? 125.927 118.491 111.538 1.00 249.50 ?  294  SER B C   1 
ATOM   4867 O O   . SER B 1 294 ? 126.535 118.190 112.563 1.00 249.50 ?  294  SER B O   1 
ATOM   4868 C CB  . SER B 1 294 ? 123.665 119.483 111.289 1.00 249.50 ?  294  SER B CB  1 
ATOM   4869 O OG  . SER B 1 294 ? 123.859 120.107 110.031 1.00 249.50 ?  294  SER B OG  1 
ATOM   4870 N N   . THR B 1 295 ? 126.509 119.097 110.511 1.00 214.64 ?  295  THR B N   1 
ATOM   4871 C CA  . THR B 1 295 ? 127.906 119.500 110.576 1.00 214.64 ?  295  THR B CA  1 
ATOM   4872 C C   . THR B 1 295 ? 127.929 121.009 110.417 1.00 214.64 ?  295  THR B C   1 
ATOM   4873 O O   . THR B 1 295 ? 128.818 121.677 110.938 1.00 214.64 ?  295  THR B O   1 
ATOM   4874 C CB  . THR B 1 295 ? 128.732 118.834 109.460 1.00 214.64 ?  295  THR B CB  1 
ATOM   4875 O OG1 . THR B 1 295 ? 129.709 119.758 108.966 1.00 214.64 ?  295  THR B OG1 1 
ATOM   4876 C CG2 . THR B 1 295 ? 127.834 118.390 108.315 1.00 214.64 ?  295  THR B CG2 1 
ATOM   4877 N N   . TYR B 1 296 ? 126.944 121.548 109.704 1.00 214.03 ?  296  TYR B N   1 
ATOM   4878 C CA  . TYR B 1 296 ? 126.850 122.992 109.497 1.00 214.03 ?  296  TYR B CA  1 
ATOM   4879 C C   . TYR B 1 296 ? 125.462 123.446 109.907 1.00 214.03 ?  296  TYR B C   1 
ATOM   4880 O O   . TYR B 1 296 ? 124.578 123.573 109.064 1.00 214.03 ?  296  TYR B O   1 
ATOM   4881 C CB  . TYR B 1 296 ? 127.083 123.341 108.030 1.00 214.03 ?  296  TYR B CB  1 
ATOM   4882 C CG  . TYR B 1 296 ? 128.456 122.973 107.530 1.00 214.03 ?  296  TYR B CG  1 
ATOM   4883 C CD1 . TYR B 1 296 ? 129.582 123.634 107.996 1.00 214.03 ?  296  TYR B CD1 1 
ATOM   4884 C CD2 . TYR B 1 296 ? 128.628 121.962 106.595 1.00 214.03 ?  296  TYR B CD2 1 
ATOM   4885 C CE1 . TYR B 1 296 ? 130.843 123.299 107.546 1.00 214.03 ?  296  TYR B CE1 1 
ATOM   4886 C CE2 . TYR B 1 296 ? 129.885 121.621 106.139 1.00 214.03 ?  296  TYR B CE2 1 
ATOM   4887 C CZ  . TYR B 1 296 ? 130.989 122.293 106.618 1.00 214.03 ?  296  TYR B CZ  1 
ATOM   4888 O OH  . TYR B 1 296 ? 132.246 121.962 106.170 1.00 214.03 ?  296  TYR B OH  1 
ATOM   4889 N N   . PHE B 1 297 ? 125.263 123.692 111.195 1.00 202.07 ?  297  PHE B N   1 
ATOM   4890 C CA  . PHE B 1 297 ? 123.950 124.082 111.690 1.00 202.07 ?  297  PHE B CA  1 
ATOM   4891 C C   . PHE B 1 297 ? 123.582 125.508 111.339 1.00 202.07 ?  297  PHE B C   1 
ATOM   4892 O O   . PHE B 1 297 ? 124.447 126.320 111.019 1.00 202.07 ?  297  PHE B O   1 
ATOM   4893 C CB  . PHE B 1 297 ? 123.856 123.880 113.205 1.00 202.07 ?  297  PHE B CB  1 
ATOM   4894 C CG  . PHE B 1 297 ? 124.518 124.966 114.013 1.00 202.07 ?  297  PHE B CG  1 
ATOM   4895 C CD1 . PHE B 1 297 ? 125.896 125.013 114.143 1.00 202.07 ?  297  PHE B CD1 1 
ATOM   4896 C CD2 . PHE B 1 297 ? 123.758 125.926 114.664 1.00 202.07 ?  297  PHE B CD2 1 
ATOM   4897 C CE1 . PHE B 1 297 ? 126.503 126.004 114.891 1.00 202.07 ?  297  PHE B CE1 1 
ATOM   4898 C CE2 . PHE B 1 297 ? 124.359 126.920 115.410 1.00 202.07 ?  297  PHE B CE2 1 
ATOM   4899 C CZ  . PHE B 1 297 ? 125.733 126.958 115.525 1.00 202.07 ?  297  PHE B CZ  1 
ATOM   4900 N N   . ALA B 1 298 ? 122.296 125.819 111.402 1.00 189.57 ?  298  ALA B N   1 
ATOM   4901 C CA  . ALA B 1 298 ? 121.852 127.174 111.139 1.00 189.57 ?  298  ALA B CA  1 
ATOM   4902 C C   . ALA B 1 298 ? 121.478 127.782 112.469 1.00 189.57 ?  298  ALA B C   1 
ATOM   4903 O O   . ALA B 1 298 ? 120.942 127.097 113.334 1.00 189.57 ?  298  ALA B O   1 
ATOM   4904 C CB  . ALA B 1 298 ? 120.663 127.161 110.207 1.00 189.57 ?  298  ALA B CB  1 
ATOM   4905 N N   . VAL B 1 299 ? 121.768 129.063 112.655 1.00 207.10 ?  299  VAL B N   1 
ATOM   4906 C CA  . VAL B 1 299 ? 121.491 129.699 113.939 1.00 207.10 ?  299  VAL B CA  1 
ATOM   4907 C C   . VAL B 1 299 ? 119.993 129.830 114.156 1.00 207.10 ?  299  VAL B C   1 
ATOM   4908 O O   . VAL B 1 299 ? 119.545 129.937 115.292 1.00 207.10 ?  299  VAL B O   1 
ATOM   4909 C CB  . VAL B 1 299 ? 122.172 131.069 114.077 1.00 207.10 ?  299  VAL B CB  1 
ATOM   4910 C CG1 . VAL B 1 299 ? 122.842 131.187 115.437 1.00 207.10 ?  299  VAL B CG1 1 
ATOM   4911 C CG2 . VAL B 1 299 ? 123.182 131.268 112.961 1.00 207.10 ?  299  VAL B CG2 1 
ATOM   4912 N N   . ARG B 1 300 ? 119.214 129.821 113.077 1.00 246.42 ?  300  ARG B N   1 
ATOM   4913 C CA  . ARG B 1 300 ? 117.770 129.858 113.235 1.00 246.42 ?  300  ARG B CA  1 
ATOM   4914 C C   . ARG B 1 300 ? 117.347 128.589 113.946 1.00 246.42 ?  300  ARG B C   1 
ATOM   4915 O O   . ARG B 1 300 ? 116.602 128.658 114.900 1.00 246.42 ?  300  ARG B O   1 
ATOM   4916 C CB  . ARG B 1 300 ? 117.041 130.023 111.903 1.00 246.42 ?  300  ARG B CB  1 
ATOM   4917 C CG  . ARG B 1 300 ? 117.618 129.246 110.733 1.00 246.42 ?  300  ARG B CG  1 
ATOM   4918 C CD  . ARG B 1 300 ? 116.565 128.335 110.124 1.00 246.42 ?  300  ARG B CD  1 
ATOM   4919 N NE  . ARG B 1 300 ? 115.226 128.897 110.274 1.00 246.42 ?  300  ARG B NE  1 
ATOM   4920 C CZ  . ARG B 1 300 ? 114.119 128.177 110.425 1.00 246.42 ?  300  ARG B CZ  1 
ATOM   4921 N NH1 . ARG B 1 300 ? 112.948 128.782 110.554 1.00 246.42 ?  300  ARG B NH1 1 
ATOM   4922 N NH2 . ARG B 1 300 ? 114.181 126.856 110.449 1.00 246.42 ?  300  ARG B NH2 1 
ATOM   4923 N N   . ASN B 1 301 ? 117.850 127.439 113.507 1.00 242.46 ?  301  ASN B N   1 
ATOM   4924 C CA  . ASN B 1 301 ? 117.504 126.168 114.125 1.00 242.46 ?  301  ASN B CA  1 
ATOM   4925 C C   . ASN B 1 301 ? 118.060 126.067 115.531 1.00 242.46 ?  301  ASN B C   1 
ATOM   4926 O O   . ASN B 1 301 ? 117.534 125.324 116.353 1.00 242.46 ?  301  ASN B O   1 
ATOM   4927 C CB  . ASN B 1 301 ? 118.004 125.006 113.277 1.00 242.46 ?  301  ASN B CB  1 
ATOM   4928 C CG  . ASN B 1 301 ? 117.244 124.866 111.979 1.00 242.46 ?  301  ASN B CG  1 
ATOM   4929 O OD1 . ASN B 1 301 ? 116.066 125.208 111.897 1.00 242.46 ?  301  ASN B OD1 1 
ATOM   4930 N ND2 . ASN B 1 301 ? 117.916 124.360 110.955 1.00 242.46 ?  301  ASN B ND2 1 
ATOM   4931 N N   . TYR B 1 302 ? 119.124 126.802 115.817 1.00 189.18 ?  302  TYR B N   1 
ATOM   4932 C CA  . TYR B 1 302 ? 119.670 126.814 117.165 1.00 189.18 ?  302  TYR B CA  1 
ATOM   4933 C C   . TYR B 1 302 ? 118.688 127.519 118.078 1.00 189.18 ?  302  TYR B C   1 
ATOM   4934 O O   . TYR B 1 302 ? 118.417 127.052 119.179 1.00 189.18 ?  302  TYR B O   1 
ATOM   4935 C CB  . TYR B 1 302 ? 121.021 127.524 117.185 1.00 189.18 ?  302  TYR B CB  1 
ATOM   4936 C CG  . TYR B 1 302 ? 121.534 127.853 118.565 1.00 189.18 ?  302  TYR B CG  1 
ATOM   4937 C CD1 . TYR B 1 302 ? 121.861 126.847 119.464 1.00 189.18 ?  302  TYR B CD1 1 
ATOM   4938 C CD2 . TYR B 1 302 ? 121.700 129.170 118.968 1.00 189.18 ?  302  TYR B CD2 1 
ATOM   4939 C CE1 . TYR B 1 302 ? 122.329 127.144 120.728 1.00 189.18 ?  302  TYR B CE1 1 
ATOM   4940 C CE2 . TYR B 1 302 ? 122.171 129.475 120.228 1.00 189.18 ?  302  TYR B CE2 1 
ATOM   4941 C CZ  . TYR B 1 302 ? 122.483 128.460 121.104 1.00 189.18 ?  302  TYR B CZ  1 
ATOM   4942 O OH  . TYR B 1 302 ? 122.953 128.764 122.360 1.00 189.18 ?  302  TYR B OH  1 
ATOM   4943 N N   . TRP B 1 303 ? 118.123 128.624 117.601 1.00 253.38 ?  303  TRP B N   1 
ATOM   4944 C CA  . TRP B 1 303 ? 117.161 129.389 118.389 1.00 253.38 ?  303  TRP B CA  1 
ATOM   4945 C C   . TRP B 1 303 ? 115.803 128.726 118.407 1.00 253.38 ?  303  TRP B C   1 
ATOM   4946 O O   . TRP B 1 303 ? 115.083 128.827 119.392 1.00 253.38 ?  303  TRP B O   1 
ATOM   4947 C CB  . TRP B 1 303 ? 117.003 130.785 117.808 1.00 253.38 ?  303  TRP B CB  1 
ATOM   4948 C CG  . TRP B 1 303 ? 118.204 131.630 117.966 1.00 253.38 ?  303  TRP B CG  1 
ATOM   4949 C CD1 . TRP B 1 303 ? 119.076 131.629 119.010 1.00 253.38 ?  303  TRP B CD1 1 
ATOM   4950 C CD2 . TRP B 1 303 ? 118.674 132.619 117.048 1.00 253.38 ?  303  TRP B CD2 1 
ATOM   4951 N NE1 . TRP B 1 303 ? 120.067 132.554 118.799 1.00 253.38 ?  303  TRP B NE1 1 
ATOM   4952 C CE2 . TRP B 1 303 ? 119.841 133.176 117.599 1.00 253.38 ?  303  TRP B CE2 1 
ATOM   4953 C CE3 . TRP B 1 303 ? 118.222 133.085 115.812 1.00 253.38 ?  303  TRP B CE3 1 
ATOM   4954 C CZ2 . TRP B 1 303 ? 120.562 134.177 116.959 1.00 253.38 ?  303  TRP B CZ2 1 
ATOM   4955 C CZ3 . TRP B 1 303 ? 118.939 134.076 115.177 1.00 253.38 ?  303  TRP B CZ3 1 
ATOM   4956 C CH2 . TRP B 1 303 ? 120.096 134.612 115.751 1.00 253.38 ?  303  TRP B CH2 1 
ATOM   4957 N N   . ARG B 1 304 ? 115.437 128.073 117.312 1.00 260.72 ?  304  ARG B N   1 
ATOM   4958 C CA  . ARG B 1 304 ? 114.160 127.379 117.252 1.00 260.72 ?  304  ARG B CA  1 
ATOM   4959 C C   . ARG B 1 304 ? 114.209 126.232 118.234 1.00 260.72 ?  304  ARG B C   1 
ATOM   4960 O O   . ARG B 1 304 ? 113.275 126.029 119.002 1.00 260.72 ?  304  ARG B O   1 
ATOM   4961 C CB  . ARG B 1 304 ? 113.898 126.862 115.844 1.00 260.72 ?  304  ARG B CB  1 
ATOM   4962 C CG  . ARG B 1 304 ? 113.405 127.916 114.870 1.00 260.72 ?  304  ARG B CG  1 
ATOM   4963 C CD  . ARG B 1 304 ? 112.356 127.374 113.913 1.00 260.72 ?  304  ARG B CD  1 
ATOM   4964 N NE  . ARG B 1 304 ? 112.645 126.027 113.436 1.00 260.72 ?  304  ARG B NE  1 
ATOM   4965 C CZ  . ARG B 1 304 ? 111.709 125.163 113.050 1.00 260.72 ?  304  ARG B CZ  1 
ATOM   4966 N NH1 . ARG B 1 304 ? 110.432 125.514 113.093 1.00 260.72 ?  304  ARG B NH1 1 
ATOM   4967 N NH2 . ARG B 1 304 ? 112.046 123.955 112.622 1.00 260.72 ?  304  ARG B NH2 1 
ATOM   4968 N N   . GLY B 1 305 ? 115.315 125.498 118.239 1.00 246.55 ?  305  GLY B N   1 
ATOM   4969 C CA  . GLY B 1 305 ? 115.478 124.397 119.167 1.00 246.55 ?  305  GLY B CA  1 
ATOM   4970 C C   . GLY B 1 305 ? 115.554 124.880 120.588 1.00 246.55 ?  305  GLY B C   1 
ATOM   4971 O O   . GLY B 1 305 ? 115.042 124.230 121.478 1.00 246.55 ?  305  GLY B O   1 
ATOM   4972 N N   . PHE B 1 306 ? 116.187 126.022 120.805 1.00 235.42 ?  306  PHE B N   1 
ATOM   4973 C CA  . PHE B 1 306 ? 116.277 126.599 122.135 1.00 235.42 ?  306  PHE B CA  1 
ATOM   4974 C C   . PHE B 1 306 ? 114.903 126.879 122.688 1.00 235.42 ?  306  PHE B C   1 
ATOM   4975 O O   . PHE B 1 306 ? 114.586 126.466 123.794 1.00 235.42 ?  306  PHE B O   1 
ATOM   4976 C CB  . PHE B 1 306 ? 117.048 127.908 122.073 1.00 235.42 ?  306  PHE B CB  1 
ATOM   4977 C CG  . PHE B 1 306 ? 118.043 128.075 123.165 1.00 235.42 ?  306  PHE B CG  1 
ATOM   4978 C CD1 . PHE B 1 306 ? 119.276 127.463 123.087 1.00 235.42 ?  306  PHE B CD1 1 
ATOM   4979 C CD2 . PHE B 1 306 ? 117.747 128.852 124.269 1.00 235.42 ?  306  PHE B CD2 1 
ATOM   4980 C CE1 . PHE B 1 306 ? 120.201 127.619 124.095 1.00 235.42 ?  306  PHE B CE1 1 
ATOM   4981 C CE2 . PHE B 1 306 ? 118.665 129.014 125.282 1.00 235.42 ?  306  PHE B CE2 1 
ATOM   4982 C CZ  . PHE B 1 306 ? 119.895 128.397 125.194 1.00 235.42 ?  306  PHE B CZ  1 
ATOM   4983 N N   . PHE B 1 307 ? 114.086 127.587 121.919 1.00 255.37 ?  307  PHE B N   1 
ATOM   4984 C CA  . PHE B 1 307 ? 112.751 127.931 122.371 1.00 255.37 ?  307  PHE B CA  1 
ATOM   4985 C C   . PHE B 1 307 ? 111.946 126.684 122.674 1.00 255.37 ?  307  PHE B C   1 
ATOM   4986 O O   . PHE B 1 307 ? 111.299 126.589 123.716 1.00 255.37 ?  307  PHE B O   1 
ATOM   4987 C CB  . PHE B 1 307 ? 112.035 128.774 121.316 1.00 255.37 ?  307  PHE B CB  1 
ATOM   4988 C CG  . PHE B 1 307 ? 110.606 129.084 121.657 1.00 255.37 ?  307  PHE B CG  1 
ATOM   4989 C CD1 . PHE B 1 307 ? 110.299 129.900 122.729 1.00 255.37 ?  307  PHE B CD1 1 
ATOM   4990 C CD2 . PHE B 1 307 ? 109.573 128.555 120.908 1.00 255.37 ?  307  PHE B CD2 1 
ATOM   4991 C CE1 . PHE B 1 307 ? 108.985 130.181 123.047 1.00 255.37 ?  307  PHE B CE1 1 
ATOM   4992 C CE2 . PHE B 1 307 ? 108.260 128.830 121.218 1.00 255.37 ?  307  PHE B CE2 1 
ATOM   4993 C CZ  . PHE B 1 307 ? 107.965 129.645 122.289 1.00 255.37 ?  307  PHE B CZ  1 
ATOM   4994 N N   . ALA B 1 308 ? 111.985 125.718 121.770 1.00 251.09 ?  308  ALA B N   1 
ATOM   4995 C CA  . ALA B 1 308 ? 111.195 124.518 121.955 1.00 251.09 ?  308  ALA B CA  1 
ATOM   4996 C C   . ALA B 1 308 ? 111.656 123.687 123.143 1.00 251.09 ?  308  ALA B C   1 
ATOM   4997 O O   . ALA B 1 308 ? 110.838 123.095 123.835 1.00 251.09 ?  308  ALA B O   1 
ATOM   4998 C CB  . ALA B 1 308 ? 111.195 123.706 120.684 1.00 251.09 ?  308  ALA B CB  1 
ATOM   4999 N N   . ALA B 1 309 ? 112.960 123.657 123.400 1.00 248.92 ?  309  ALA B N   1 
ATOM   5000 C CA  . ALA B 1 309 ? 113.491 122.898 124.523 1.00 248.92 ?  309  ALA B CA  1 
ATOM   5001 C C   . ALA B 1 309 ? 113.205 123.560 125.859 1.00 248.92 ?  309  ALA B C   1 
ATOM   5002 O O   . ALA B 1 309 ? 113.059 122.883 126.869 1.00 248.92 ?  309  ALA B O   1 
ATOM   5003 C CB  . ALA B 1 309 ? 114.980 122.677 124.359 1.00 248.92 ?  309  ALA B CB  1 
ATOM   5004 N N   . THR B 1 310 ? 113.124 124.883 125.875 1.00 278.73 ?  310  THR B N   1 
ATOM   5005 C CA  . THR B 1 310 ? 112.796 125.575 127.110 1.00 278.73 ?  310  THR B CA  1 
ATOM   5006 C C   . THR B 1 310 ? 111.320 125.438 127.389 1.00 278.73 ?  310  THR B C   1 
ATOM   5007 O O   . THR B 1 310 ? 110.906 125.458 128.542 1.00 278.73 ?  310  THR B O   1 
ATOM   5008 C CB  . THR B 1 310 ? 113.207 127.056 127.089 1.00 278.73 ?  310  THR B CB  1 
ATOM   5009 O OG1 . THR B 1 310 ? 112.688 127.687 125.916 1.00 278.73 ?  310  THR B OG1 1 
ATOM   5010 C CG2 . THR B 1 310 ? 114.720 127.187 127.105 1.00 278.73 ?  310  THR B CG2 1 
ATOM   5011 N N   . PHE B 1 311 ? 110.513 125.283 126.345 1.00 245.67 ?  311  PHE B N   1 
ATOM   5012 C CA  . PHE B 1 311 ? 109.097 125.042 126.569 1.00 245.67 ?  311  PHE B CA  1 
ATOM   5013 C C   . PHE B 1 311 ? 108.952 123.660 127.159 1.00 245.67 ?  311  PHE B C   1 
ATOM   5014 O O   . PHE B 1 311 ? 108.181 123.466 128.087 1.00 245.67 ?  311  PHE B O   1 
ATOM   5015 C CB  . PHE B 1 311 ? 108.288 125.156 125.284 1.00 245.67 ?  311  PHE B CB  1 
ATOM   5016 C CG  . PHE B 1 311 ? 106.832 125.386 125.524 1.00 245.67 ?  311  PHE B CG  1 
ATOM   5017 C CD1 . PHE B 1 311 ? 106.376 126.631 125.908 1.00 245.67 ?  311  PHE B CD1 1 
ATOM   5018 C CD2 . PHE B 1 311 ? 105.925 124.354 125.400 1.00 245.67 ?  311  PHE B CD2 1 
ATOM   5019 C CE1 . PHE B 1 311 ? 105.036 126.849 126.144 1.00 245.67 ?  311  PHE B CE1 1 
ATOM   5020 C CE2 . PHE B 1 311 ? 104.583 124.562 125.637 1.00 245.67 ?  311  PHE B CE2 1 
ATOM   5021 C CZ  . PHE B 1 311 ? 104.136 125.812 126.010 1.00 245.67 ?  311  PHE B CZ  1 
ATOM   5022 N N   . SER B 1 312 ? 109.708 122.700 126.641 1.00 245.26 ?  312  SER B N   1 
ATOM   5023 C CA  . SER B 1 312 ? 109.686 121.355 127.188 1.00 245.26 ?  312  SER B CA  1 
ATOM   5024 C C   . SER B 1 312 ? 110.035 121.382 128.662 1.00 245.26 ?  312  SER B C   1 
ATOM   5025 O O   . SER B 1 312 ? 109.368 120.750 129.467 1.00 245.26 ?  312  SER B O   1 
ATOM   5026 C CB  . SER B 1 312 ? 110.684 120.479 126.438 1.00 245.26 ?  312  SER B CB  1 
ATOM   5027 O OG  . SER B 1 312 ? 110.063 119.326 125.906 1.00 245.26 ?  312  SER B OG  1 
ATOM   5028 N N   . ALA B 1 313 ? 111.073 122.127 129.024 1.00 226.87 ?  313  ALA B N   1 
ATOM   5029 C CA  . ALA B 1 313 ? 111.487 122.229 130.416 1.00 226.87 ?  313  ALA B CA  1 
ATOM   5030 C C   . ALA B 1 313 ? 110.431 122.849 131.307 1.00 226.87 ?  313  ALA B C   1 
ATOM   5031 O O   . ALA B 1 313 ? 110.266 122.439 132.449 1.00 226.87 ?  313  ALA B O   1 
ATOM   5032 C CB  . ALA B 1 313 ? 112.772 123.023 130.508 1.00 226.87 ?  313  ALA B CB  1 
ATOM   5033 N N   . PHE B 1 314 ? 109.721 123.843 130.798 1.00 245.76 ?  314  PHE B N   1 
ATOM   5034 C CA  . PHE B 1 314 ? 108.670 124.486 131.573 1.00 245.76 ?  314  PHE B CA  1 
ATOM   5035 C C   . PHE B 1 314 ? 107.524 123.511 131.816 1.00 245.76 ?  314  PHE B C   1 
ATOM   5036 O O   . PHE B 1 314 ? 107.009 123.423 132.928 1.00 245.76 ?  314  PHE B O   1 
ATOM   5037 C CB  . PHE B 1 314 ? 108.222 125.785 130.876 1.00 245.76 ?  314  PHE B CB  1 
ATOM   5038 C CG  . PHE B 1 314 ? 106.747 126.067 130.956 1.00 245.76 ?  314  PHE B CG  1 
ATOM   5039 C CD1 . PHE B 1 314 ? 106.189 126.612 132.102 1.00 245.76 ?  314  PHE B CD1 1 
ATOM   5040 C CD2 . PHE B 1 314 ? 105.926 125.831 129.866 1.00 245.76 ?  314  PHE B CD2 1 
ATOM   5041 C CE1 . PHE B 1 314 ? 104.837 126.875 132.171 1.00 245.76 ?  314  PHE B CE1 1 
ATOM   5042 C CE2 . PHE B 1 314 ? 104.573 126.089 129.930 1.00 245.76 ?  314  PHE B CE2 1 
ATOM   5043 C CZ  . PHE B 1 314 ? 104.028 126.616 131.082 1.00 245.76 ?  314  PHE B CZ  1 
ATOM   5044 N N   . VAL B 1 315 ? 107.138 122.761 130.788 1.00 246.86 ?  315  VAL B N   1 
ATOM   5045 C CA  . VAL B 1 315 ? 106.059 121.802 130.938 1.00 246.86 ?  315  VAL B CA  1 
ATOM   5046 C C   . VAL B 1 315 ? 106.501 120.742 131.929 1.00 246.86 ?  315  VAL B C   1 
ATOM   5047 O O   . VAL B 1 315 ? 105.742 120.350 132.801 1.00 246.86 ?  315  VAL B O   1 
ATOM   5048 C CB  . VAL B 1 315 ? 105.640 121.190 129.585 1.00 246.86 ?  315  VAL B CB  1 
ATOM   5049 C CG1 . VAL B 1 315 ? 104.515 120.182 129.759 1.00 246.86 ?  315  VAL B CG1 1 
ATOM   5050 C CG2 . VAL B 1 315 ? 105.183 122.280 128.638 1.00 246.86 ?  315  VAL B CG2 1 
ATOM   5051 N N   . PHE B 1 316 ? 107.753 120.316 131.831 1.00 202.01 ?  316  PHE B N   1 
ATOM   5052 C CA  . PHE B 1 316 ? 108.295 119.330 132.764 1.00 202.01 ?  316  PHE B CA  1 
ATOM   5053 C C   . PHE B 1 316 ? 108.189 119.803 134.199 1.00 202.01 ?  316  PHE B C   1 
ATOM   5054 O O   . PHE B 1 316 ? 107.873 119.016 135.082 1.00 202.01 ?  316  PHE B O   1 
ATOM   5055 C CB  . PHE B 1 316 ? 109.756 119.093 132.445 1.00 202.01 ?  316  PHE B CB  1 
ATOM   5056 C CG  . PHE B 1 316 ? 110.065 117.693 132.053 1.00 202.01 ?  316  PHE B CG  1 
ATOM   5057 C CD1 . PHE B 1 316 ? 109.055 116.807 131.757 1.00 202.01 ?  316  PHE B CD1 1 
ATOM   5058 C CD2 . PHE B 1 316 ? 111.372 117.262 131.984 1.00 202.01 ?  316  PHE B CD2 1 
ATOM   5059 C CE1 . PHE B 1 316 ? 109.346 115.513 131.396 1.00 202.01 ?  316  PHE B CE1 1 
ATOM   5060 C CE2 . PHE B 1 316 ? 111.667 115.966 131.631 1.00 202.01 ?  316  PHE B CE2 1 
ATOM   5061 C CZ  . PHE B 1 316 ? 110.650 115.088 131.339 1.00 202.01 ?  316  PHE B CZ  1 
ATOM   5062 N N   . ARG B 1 317 ? 108.459 121.079 134.439 1.00 206.32 ?  317  ARG B N   1 
ATOM   5063 C CA  . ARG B 1 317 ? 108.413 121.636 135.784 1.00 206.32 ?  317  ARG B CA  1 
ATOM   5064 C C   . ARG B 1 317 ? 107.008 121.640 136.349 1.00 206.32 ?  317  ARG B C   1 
ATOM   5065 O O   . ARG B 1 317 ? 106.818 121.291 137.504 1.00 206.32 ?  317  ARG B O   1 
ATOM   5066 C CB  . ARG B 1 317 ? 108.972 123.055 135.788 1.00 206.32 ?  317  ARG B CB  1 
ATOM   5067 C CG  . ARG B 1 317 ? 110.284 123.195 136.537 1.00 206.32 ?  317  ARG B CG  1 
ATOM   5068 C CD  . ARG B 1 317 ? 111.458 123.323 135.581 1.00 206.32 ?  317  ARG B CD  1 
ATOM   5069 N NE  . ARG B 1 317 ? 111.797 122.048 134.958 1.00 206.32 ?  317  ARG B NE  1 
ATOM   5070 C CZ  . ARG B 1 317 ? 113.017 121.711 134.556 1.00 206.32 ?  317  ARG B CZ  1 
ATOM   5071 N NH1 . ARG B 1 317 ? 113.230 120.528 133.999 1.00 206.32 ?  317  ARG B NH1 1 
ATOM   5072 N NH2 . ARG B 1 317 ? 114.025 122.559 134.710 1.00 206.32 ?  317  ARG B NH2 1 
ATOM   5073 N N   . VAL B 1 318 ? 106.025 122.036 135.547 1.00 221.29 ?  318  VAL B N   1 
ATOM   5074 C CA  . VAL B 1 318 ? 104.642 122.004 136.013 1.00 221.29 ?  318  VAL B CA  1 
ATOM   5075 C C   . VAL B 1 318 ? 104.105 120.583 136.181 1.00 221.29 ?  318  VAL B C   1 
ATOM   5076 O O   . VAL B 1 318 ? 103.243 120.353 137.017 1.00 221.29 ?  318  VAL B O   1 
ATOM   5077 C CB  . VAL B 1 318 ? 103.698 122.915 135.191 1.00 221.29 ?  318  VAL B CB  1 
ATOM   5078 C CG1 . VAL B 1 318 ? 104.305 124.297 135.044 1.00 221.29 ?  318  VAL B CG1 1 
ATOM   5079 C CG2 . VAL B 1 318 ? 103.363 122.326 133.834 1.00 221.29 ?  318  VAL B CG2 1 
ATOM   5080 N N   . LEU B 1 319 ? 104.640 119.621 135.434 1.00 214.33 ?  319  LEU B N   1 
ATOM   5081 C CA  . LEU B 1 319 ? 104.226 118.235 135.598 1.00 214.33 ?  319  LEU B CA  1 
ATOM   5082 C C   . LEU B 1 319 ? 104.804 117.738 136.898 1.00 214.33 ?  319  LEU B C   1 
ATOM   5083 O O   . LEU B 1 319 ? 104.164 116.977 137.621 1.00 214.33 ?  319  LEU B O   1 
ATOM   5084 C CB  . LEU B 1 319 ? 104.740 117.389 134.446 1.00 214.33 ?  319  LEU B CB  1 
ATOM   5085 C CG  . LEU B 1 319 ? 103.909 117.365 133.170 1.00 214.33 ?  319  LEU B CG  1 
ATOM   5086 C CD1 . LEU B 1 319 ? 104.802 117.062 131.978 1.00 214.33 ?  319  LEU B CD1 1 
ATOM   5087 C CD2 . LEU B 1 319 ? 102.806 116.329 133.293 1.00 214.33 ?  319  LEU B CD2 1 
ATOM   5088 N N   . ALA B 1 320 ? 106.022 118.170 137.205 1.00 212.63 ?  320  ALA B N   1 
ATOM   5089 C CA  . ALA B 1 320 ? 106.670 117.771 138.448 1.00 212.63 ?  320  ALA B CA  1 
ATOM   5090 C C   . ALA B 1 320 ? 106.110 118.563 139.607 1.00 212.63 ?  320  ALA B C   1 
ATOM   5091 O O   . ALA B 1 320 ? 106.638 118.506 140.711 1.00 212.63 ?  320  ALA B O   1 
ATOM   5092 C CB  . ALA B 1 320 ? 108.169 117.970 138.350 1.00 212.63 ?  320  ALA B CB  1 
ATOM   5093 N N   . VAL B 1 321 ? 105.051 119.318 139.361 1.00 232.14 ?  321  VAL B N   1 
ATOM   5094 C CA  . VAL B 1 321 ? 104.411 120.065 140.429 1.00 232.14 ?  321  VAL B CA  1 
ATOM   5095 C C   . VAL B 1 321 ? 103.072 119.395 140.642 1.00 232.14 ?  321  VAL B C   1 
ATOM   5096 O O   . VAL B 1 321 ? 102.649 119.172 141.778 1.00 232.14 ?  321  VAL B O   1 
ATOM   5097 C CB  . VAL B 1 321 ? 104.258 121.559 140.059 1.00 232.14 ?  321  VAL B CB  1 
ATOM   5098 C CG1 . VAL B 1 321 ? 103.017 122.188 140.676 1.00 232.14 ?  321  VAL B CG1 1 
ATOM   5099 C CG2 . VAL B 1 321 ? 105.500 122.334 140.464 1.00 232.14 ?  321  VAL B CG2 1 
ATOM   5100 N N   . TRP B 1 322 ? 102.426 119.011 139.547 1.00 263.41 ?  322  TRP B N   1 
ATOM   5101 C CA  . TRP B 1 322 ? 101.119 118.377 139.640 1.00 263.41 ?  322  TRP B CA  1 
ATOM   5102 C C   . TRP B 1 322 ? 101.216 117.051 140.357 1.00 263.41 ?  322  TRP B C   1 
ATOM   5103 O O   . TRP B 1 322 ? 100.370 116.721 141.183 1.00 263.41 ?  322  TRP B O   1 
ATOM   5104 C CB  . TRP B 1 322 ? 100.534 118.165 138.250 1.00 263.41 ?  322  TRP B CB  1 
ATOM   5105 C CG  . TRP B 1 322 ? 100.208 119.436 137.552 1.00 263.41 ?  322  TRP B CG  1 
ATOM   5106 C CD1 . TRP B 1 322 ? 99.888  120.630 138.128 1.00 263.41 ?  322  TRP B CD1 1 
ATOM   5107 C CD2 . TRP B 1 322 ? 100.175 119.650 136.138 1.00 263.41 ?  322  TRP B CD2 1 
ATOM   5108 N NE1 . TRP B 1 322 ? 99.657  121.574 137.160 1.00 263.41 ?  322  TRP B NE1 1 
ATOM   5109 C CE2 . TRP B 1 322 ? 99.828  120.997 135.930 1.00 263.41 ?  322  TRP B CE2 1 
ATOM   5110 C CE3 . TRP B 1 322 ? 100.407 118.832 135.030 1.00 263.41 ?  322  TRP B CE3 1 
ATOM   5111 C CZ2 . TRP B 1 322 ? 99.701  121.545 134.657 1.00 263.41 ?  322  TRP B CZ2 1 
ATOM   5112 C CZ3 . TRP B 1 322 ? 100.285 119.377 133.768 1.00 263.41 ?  322  TRP B CZ3 1 
ATOM   5113 C CH2 . TRP B 1 322 ? 99.934  120.719 133.591 1.00 263.41 ?  322  TRP B CH2 1 
ATOM   5114 N N   . ASN B 1 323 ? 102.258 116.282 140.047 1.00 237.10 ?  323  ASN B N   1 
ATOM   5115 C CA  . ASN B 1 323 ? 102.444 114.971 140.662 1.00 237.10 ?  323  ASN B CA  1 
ATOM   5116 C C   . ASN B 1 323 ? 103.547 115.031 141.688 1.00 237.10 ?  323  ASN B C   1 
ATOM   5117 O O   . ASN B 1 323 ? 104.122 113.997 142.028 1.00 237.10 ?  323  ASN B O   1 
ATOM   5118 C CB  . ASN B 1 323 ? 102.815 113.943 139.598 1.00 237.10 ?  323  ASN B CB  1 
ATOM   5119 C CG  . ASN B 1 323 ? 102.004 112.668 139.706 1.00 237.10 ?  323  ASN B CG  1 
ATOM   5120 O OD1 . ASN B 1 323 ? 101.150 112.390 138.867 1.00 237.10 ?  323  ASN B OD1 1 
ATOM   5121 N ND2 . ASN B 1 323 ? 102.272 111.882 140.741 1.00 237.10 ?  323  ASN B ND2 1 
ATOM   5122 N N   . LYS B 1 324 ? 103.850 116.227 142.179 1.00 232.23 ?  324  LYS B N   1 
ATOM   5123 C CA  . LYS B 1 324 ? 104.936 116.413 143.151 1.00 232.23 ?  324  LYS B CA  1 
ATOM   5124 C C   . LYS B 1 324 ? 106.184 115.619 142.820 1.00 232.23 ?  324  LYS B C   1 
ATOM   5125 O O   . LYS B 1 324 ? 106.674 114.862 143.659 1.00 232.23 ?  324  LYS B O   1 
ATOM   5126 C CB  . LYS B 1 324 ? 104.471 116.152 144.586 1.00 232.23 ?  324  LYS B CB  1 
ATOM   5127 C CG  . LYS B 1 324 ? 104.673 117.345 145.509 1.00 232.23 ?  324  LYS B CG  1 
ATOM   5128 C CD  . LYS B 1 324 ? 104.443 118.661 144.778 1.00 232.23 ?  324  LYS B CD  1 
ATOM   5129 C CE  . LYS B 1 324 ? 105.622 119.612 144.930 1.00 232.23 ?  324  LYS B CE  1 
ATOM   5130 N NZ  . LYS B 1 324 ? 106.353 119.790 143.644 1.00 232.23 ?  324  LYS B NZ  1 
ATOM   5131 N N   . ASP B 1 325 ? 106.691 115.792 141.604 1.00 221.52 ?  325  ASP B N   1 
ATOM   5132 C CA  . ASP B 1 325 ? 107.889 115.085 141.159 1.00 221.52 ?  325  ASP B CA  1 
ATOM   5133 C C   . ASP B 1 325 ? 107.920 113.605 141.461 1.00 221.52 ?  325  ASP B C   1 
ATOM   5134 O O   . ASP B 1 325 ? 107.066 112.875 140.950 1.00 221.52 ?  325  ASP B O   1 
ATOM   5135 C CB  . ASP B 1 325 ? 109.158 115.762 141.679 1.00 221.52 ?  325  ASP B CB  1 
ATOM   5136 C CG  . ASP B 1 325 ? 110.156 116.031 140.578 1.00 221.52 ?  325  ASP B CG  1 
ATOM   5137 O OD1 . ASP B 1 325 ? 110.237 115.214 139.634 1.00 221.52 ?  325  ASP B OD1 1 
ATOM   5138 O OD2 . ASP B 1 325 ? 110.853 117.065 140.648 1.00 221.52 ?  325  ASP B OD2 1 
ATOM   5139 N N   . ALA B 1 326 ? 108.906 113.160 142.244 1.00 234.28 ?  326  ALA B N   1 
ATOM   5140 C CA  . ALA B 1 326 ? 109.089 111.732 142.570 1.00 234.28 ?  326  ALA B CA  1 
ATOM   5141 C C   . ALA B 1 326 ? 109.486 110.862 141.377 1.00 234.28 ?  326  ALA B C   1 
ATOM   5142 O O   . ALA B 1 326 ? 109.606 109.645 141.515 1.00 234.28 ?  326  ALA B O   1 
ATOM   5143 C CB  . ALA B 1 326 ? 107.903 111.141 143.341 1.00 234.28 ?  326  ALA B CB  1 
ATOM   5144 N N   . VAL B 1 327 ? 109.710 111.477 140.216 1.00 229.27 ?  327  VAL B N   1 
ATOM   5145 C CA  . VAL B 1 327 ? 110.131 110.736 139.031 1.00 229.27 ?  327  VAL B CA  1 
ATOM   5146 C C   . VAL B 1 327 ? 111.246 111.481 138.330 1.00 229.27 ?  327  VAL B C   1 
ATOM   5147 O O   . VAL B 1 327 ? 112.046 112.135 139.000 1.00 229.27 ?  327  VAL B O   1 
ATOM   5148 C CB  . VAL B 1 327 ? 108.977 110.509 138.029 1.00 229.27 ?  327  VAL B CB  1 
ATOM   5149 C CG1 . VAL B 1 327 ? 108.232 109.238 138.376 1.00 229.27 ?  327  VAL B CG1 1 
ATOM   5150 C CG2 . VAL B 1 327 ? 108.034 111.703 137.983 1.00 229.27 ?  327  VAL B CG2 1 
ATOM   5151 N N   . THR B 1 328 ? 111.309 111.386 137.000 1.00 244.65 ?  328  THR B N   1 
ATOM   5152 C CA  . THR B 1 328 ? 112.332 112.082 136.196 1.00 244.65 ?  328  THR B CA  1 
ATOM   5153 C C   . THR B 1 328 ? 113.794 111.877 136.586 1.00 244.65 ?  328  THR B C   1 
ATOM   5154 O O   . THR B 1 328 ? 114.138 110.936 137.302 1.00 244.65 ?  328  THR B O   1 
ATOM   5155 C CB  . THR B 1 328 ? 112.040 113.600 136.019 1.00 244.65 ?  328  THR B CB  1 
ATOM   5156 O OG1 . THR B 1 328 ? 112.338 114.312 137.228 1.00 244.65 ?  328  THR B OG1 1 
ATOM   5157 C CG2 . THR B 1 328 ? 110.589 113.841 135.620 1.00 244.65 ?  328  THR B CG2 1 
ATOM   5158 N N   . ILE B 1 329 ? 114.666 112.732 136.066 1.00 242.79 ?  329  ILE B N   1 
ATOM   5159 C CA  . ILE B 1 329 ? 116.088 112.633 136.375 1.00 242.79 ?  329  ILE B CA  1 
ATOM   5160 C C   . ILE B 1 329 ? 116.561 114.040 136.624 1.00 242.79 ?  329  ILE B C   1 
ATOM   5161 O O   . ILE B 1 329 ? 117.714 114.261 136.974 1.00 242.79 ?  329  ILE B O   1 
ATOM   5162 C CB  . ILE B 1 329 ? 116.886 112.029 135.215 1.00 242.79 ?  329  ILE B CB  1 
ATOM   5163 C CG1 . ILE B 1 329 ? 116.172 112.305 133.903 1.00 242.79 ?  329  ILE B CG1 1 
ATOM   5164 C CG2 . ILE B 1 329 ? 117.025 110.527 135.388 1.00 242.79 ?  329  ILE B CG2 1 
ATOM   5165 C CD1 . ILE B 1 329 ? 115.870 111.055 133.117 1.00 242.79 ?  329  ILE B CD1 1 
ATOM   5166 N N   . THR B 1 330 ? 115.671 115.003 136.423 1.00 225.17 ?  330  THR B N   1 
ATOM   5167 C CA  . THR B 1 330 ? 116.014 116.376 136.729 1.00 225.17 ?  330  THR B CA  1 
ATOM   5168 C C   . THR B 1 330 ? 115.836 116.517 138.224 1.00 225.17 ?  330  THR B C   1 
ATOM   5169 O O   . THR B 1 330 ? 116.557 117.270 138.869 1.00 225.17 ?  330  THR B O   1 
ATOM   5170 C CB  . THR B 1 330 ? 115.099 117.377 135.999 1.00 225.17 ?  330  THR B CB  1 
ATOM   5171 O OG1 . THR B 1 330 ? 114.318 118.104 136.956 1.00 225.17 ?  330  THR B OG1 1 
ATOM   5172 C CG2 . THR B 1 330 ? 114.167 116.659 135.039 1.00 225.17 ?  330  THR B CG2 1 
ATOM   5173 N N   . ALA B 1 331 ? 114.870 115.792 138.780 1.00 212.90 ?  331  ALA B N   1 
ATOM   5174 C CA  . ALA B 1 331 ? 114.659 115.813 140.219 1.00 212.90 ?  331  ALA B CA  1 
ATOM   5175 C C   . ALA B 1 331 ? 115.920 115.349 140.892 1.00 212.90 ?  331  ALA B C   1 
ATOM   5176 O O   . ALA B 1 331 ? 116.385 115.962 141.851 1.00 212.90 ?  331  ALA B O   1 
ATOM   5177 C CB  . ALA B 1 331 ? 113.532 114.875 140.589 1.00 212.90 ?  331  ALA B CB  1 
ATOM   5178 N N   . LEU B 1 332 ? 116.482 114.257 140.387 1.00 197.67 ?  332  LEU B N   1 
ATOM   5179 C CA  . LEU B 1 332 ? 117.677 113.699 140.999 1.00 197.67 ?  332  LEU B CA  1 
ATOM   5180 C C   . LEU B 1 332 ? 118.901 114.203 140.267 1.00 197.67 ?  332  LEU B C   1 
ATOM   5181 O O   . LEU B 1 332 ? 118.814 115.202 139.552 1.00 197.67 ?  332  LEU B O   1 
ATOM   5182 C CB  . LEU B 1 332 ? 117.641 112.171 140.967 1.00 197.67 ?  332  LEU B CB  1 
ATOM   5183 C CG  . LEU B 1 332 ? 116.487 111.499 140.216 1.00 197.67 ?  332  LEU B CG  1 
ATOM   5184 C CD1 . LEU B 1 332 ? 116.987 110.274 139.469 1.00 197.67 ?  332  LEU B CD1 1 
ATOM   5185 C CD2 . LEU B 1 332 ? 115.365 111.111 141.168 1.00 197.67 ?  332  LEU B CD2 1 
ATOM   5186 N N   . PHE B 1 333 ? 120.032 113.523 140.439 1.00 196.18 ?  333  PHE B N   1 
ATOM   5187 C CA  . PHE B 1 333 ? 121.284 113.910 139.777 1.00 196.18 ?  333  PHE B CA  1 
ATOM   5188 C C   . PHE B 1 333 ? 121.742 115.288 140.233 1.00 196.18 ?  333  PHE B C   1 
ATOM   5189 O O   . PHE B 1 333 ? 122.839 115.712 139.887 1.00 196.18 ?  333  PHE B O   1 
ATOM   5190 C CB  . PHE B 1 333 ? 121.183 113.883 138.240 1.00 196.18 ?  333  PHE B CB  1 
ATOM   5191 C CG  . PHE B 1 333 ? 120.926 112.522 137.644 1.00 196.18 ?  333  PHE B CG  1 
ATOM   5192 C CD1 . PHE B 1 333 ? 120.606 111.426 138.429 1.00 196.18 ?  333  PHE B CD1 1 
ATOM   5193 C CD2 . PHE B 1 333 ? 121.003 112.349 136.274 1.00 196.18 ?  333  PHE B CD2 1 
ATOM   5194 C CE1 . PHE B 1 333 ? 120.365 110.194 137.861 1.00 196.18 ?  333  PHE B CE1 1 
ATOM   5195 C CE2 . PHE B 1 333 ? 120.770 111.117 135.699 1.00 196.18 ?  333  PHE B CE2 1 
ATOM   5196 C CZ  . PHE B 1 333 ? 120.450 110.038 136.494 1.00 196.18 ?  333  PHE B CZ  1 
ATOM   5197 N N   . ARG B 1 334 ? 120.919 115.985 141.012 1.00 237.12 ?  334  ARG B N   1 
ATOM   5198 C CA  . ARG B 1 334 ? 121.260 117.315 141.449 1.00 237.12 ?  334  ARG B CA  1 
ATOM   5199 C C   . ARG B 1 334 ? 122.293 117.174 142.539 1.00 237.12 ?  334  ARG B C   1 
ATOM   5200 O O   . ARG B 1 334 ? 122.011 116.627 143.602 1.00 237.12 ?  334  ARG B O   1 
ATOM   5201 C CB  . ARG B 1 334 ? 120.024 118.058 141.942 1.00 237.12 ?  334  ARG B CB  1 
ATOM   5202 C CG  . ARG B 1 334 ? 119.629 119.232 141.063 1.00 237.12 ?  334  ARG B CG  1 
ATOM   5203 C CD  . ARG B 1 334 ? 119.515 118.817 139.608 1.00 237.12 ?  334  ARG B CD  1 
ATOM   5204 N NE  . ARG B 1 334 ? 118.939 119.868 138.779 1.00 237.12 ?  334  ARG B NE  1 
ATOM   5205 C CZ  . ARG B 1 334 ? 118.598 119.712 137.505 1.00 237.12 ?  334  ARG B CZ  1 
ATOM   5206 N NH1 . ARG B 1 334 ? 118.776 118.544 136.906 1.00 237.12 ?  334  ARG B NH1 1 
ATOM   5207 N NH2 . ARG B 1 334 ? 118.080 120.725 136.827 1.00 237.12 ?  334  ARG B NH2 1 
ATOM   5208 N N   . THR B 1 335 ? 123.494 117.658 142.278 1.00 241.14 ?  335  THR B N   1 
ATOM   5209 C CA  . THR B 1 335 ? 124.586 117.542 143.224 1.00 241.14 ?  335  THR B CA  1 
ATOM   5210 C C   . THR B 1 335 ? 124.675 118.681 144.207 1.00 241.14 ?  335  THR B C   1 
ATOM   5211 O O   . THR B 1 335 ? 124.217 119.786 143.934 1.00 241.14 ?  335  THR B O   1 
ATOM   5212 C CB  . THR B 1 335 ? 125.920 117.443 142.499 1.00 241.14 ?  335  THR B CB  1 
ATOM   5213 O OG1 . THR B 1 335 ? 126.123 118.626 141.726 1.00 241.14 ?  335  THR B OG1 1 
ATOM   5214 C CG2 . THR B 1 335 ? 125.928 116.240 141.605 1.00 241.14 ?  335  THR B CG2 1 
ATOM   5215 N N   . ASN B 1 336 ? 125.236 118.404 145.378 1.00 222.54 ?  336  ASN B N   1 
ATOM   5216 C CA  . ASN B 1 336 ? 125.349 119.416 146.413 1.00 222.54 ?  336  ASN B CA  1 
ATOM   5217 C C   . ASN B 1 336 ? 126.798 119.517 146.811 1.00 222.54 ?  336  ASN B C   1 
ATOM   5218 O O   . ASN B 1 336 ? 127.148 119.299 147.965 1.00 222.54 ?  336  ASN B O   1 
ATOM   5219 C CB  . ASN B 1 336 ? 124.505 119.036 147.629 1.00 222.54 ?  336  ASN B CB  1 
ATOM   5220 C CG  . ASN B 1 336 ? 123.352 118.114 147.281 1.00 222.54 ?  336  ASN B CG  1 
ATOM   5221 O OD1 . ASN B 1 336 ? 122.367 118.536 146.675 1.00 222.54 ?  336  ASN B OD1 1 
ATOM   5222 N ND2 . ASN B 1 336 ? 123.468 116.848 147.665 1.00 222.54 ?  336  ASN B ND2 1 
ATOM   5223 N N   . PHE B 1 337 ? 127.650 119.835 145.848 1.00 245.34 ?  337  PHE B N   1 
ATOM   5224 C CA  . PHE B 1 337 ? 129.075 119.933 146.121 1.00 245.34 ?  337  PHE B CA  1 
ATOM   5225 C C   . PHE B 1 337 ? 129.384 121.296 146.675 1.00 245.34 ?  337  PHE B C   1 
ATOM   5226 O O   . PHE B 1 337 ? 128.989 122.309 146.107 1.00 245.34 ?  337  PHE B O   1 
ATOM   5227 C CB  . PHE B 1 337 ? 129.894 119.728 144.852 1.00 245.34 ?  337  PHE B CB  1 
ATOM   5228 C CG  . PHE B 1 337 ? 129.674 118.405 144.188 1.00 245.34 ?  337  PHE B CG  1 
ATOM   5229 C CD1 . PHE B 1 337 ? 129.375 117.277 144.930 1.00 245.34 ?  337  PHE B CD1 1 
ATOM   5230 C CD2 . PHE B 1 337 ? 129.781 118.291 142.817 1.00 245.34 ?  337  PHE B CD2 1 
ATOM   5231 C CE1 . PHE B 1 337 ? 129.175 116.065 144.316 1.00 245.34 ?  337  PHE B CE1 1 
ATOM   5232 C CE2 . PHE B 1 337 ? 129.585 117.080 142.198 1.00 245.34 ?  337  PHE B CE2 1 
ATOM   5233 C CZ  . PHE B 1 337 ? 129.279 115.966 142.950 1.00 245.34 ?  337  PHE B CZ  1 
ATOM   5234 N N   . ARG B 1 338 ? 130.148 121.355 147.760 1.00 255.26 ?  338  ARG B N   1 
ATOM   5235 C CA  . ARG B 1 338 ? 130.582 122.650 148.280 1.00 255.26 ?  338  ARG B CA  1 
ATOM   5236 C C   . ARG B 1 338 ? 131.995 122.882 147.785 1.00 255.26 ?  338  ARG B C   1 
ATOM   5237 O O   . ARG B 1 338 ? 132.953 122.399 148.383 1.00 255.26 ?  338  ARG B O   1 
ATOM   5238 C CB  . ARG B 1 338 ? 130.547 122.676 149.805 1.00 255.26 ?  338  ARG B CB  1 
ATOM   5239 C CG  . ARG B 1 338 ? 129.861 123.900 150.397 1.00 255.26 ?  338  ARG B CG  1 
ATOM   5240 C CD  . ARG B 1 338 ? 130.740 125.146 150.367 1.00 255.26 ?  338  ARG B CD  1 
ATOM   5241 N NE  . ARG B 1 338 ? 132.159 124.849 150.558 1.00 255.26 ?  338  ARG B NE  1 
ATOM   5242 C CZ  . ARG B 1 338 ? 133.148 125.587 150.063 1.00 255.26 ?  338  ARG B CZ  1 
ATOM   5243 N NH1 . ARG B 1 338 ? 134.409 125.242 150.280 1.00 255.26 ?  338  ARG B NH1 1 
ATOM   5244 N NH2 . ARG B 1 338 ? 132.875 126.670 149.351 1.00 255.26 ?  338  ARG B NH2 1 
ATOM   5245 N N   . MET B 1 339 ? 132.136 123.621 146.693 1.00 275.55 ?  339  MET B N   1 
ATOM   5246 C CA  . MET B 1 339 ? 133.458 123.826 146.113 1.00 275.55 ?  339  MET B CA  1 
ATOM   5247 C C   . MET B 1 339 ? 134.023 125.209 146.382 1.00 275.55 ?  339  MET B C   1 
ATOM   5248 O O   . MET B 1 339 ? 133.298 126.200 146.327 1.00 275.55 ?  339  MET B O   1 
ATOM   5249 C CB  . MET B 1 339 ? 133.410 123.559 144.607 1.00 275.55 ?  339  MET B CB  1 
ATOM   5250 C CG  . MET B 1 339 ? 134.719 123.068 144.008 1.00 275.55 ?  339  MET B CG  1 
ATOM   5251 S SD  . MET B 1 339 ? 135.125 121.395 144.535 1.00 275.55 ?  339  MET B SD  1 
ATOM   5252 C CE  . MET B 1 339 ? 133.506 120.637 144.471 1.00 275.55 ?  339  MET B CE  1 
ATOM   5253 N N   . ASP B 1 340 ? 135.318 125.279 146.671 1.00 278.57 ?  340  ASP B N   1 
ATOM   5254 C CA  . ASP B 1 340 ? 135.942 126.576 146.882 1.00 278.57 ?  340  ASP B CA  1 
ATOM   5255 C C   . ASP B 1 340 ? 136.189 127.292 145.574 1.00 278.57 ?  340  ASP B C   1 
ATOM   5256 O O   . ASP B 1 340 ? 136.524 126.663 144.572 1.00 278.57 ?  340  ASP B O   1 
ATOM   5257 C CB  . ASP B 1 340 ? 137.220 126.474 147.702 1.00 278.57 ?  340  ASP B CB  1 
ATOM   5258 C CG  . ASP B 1 340 ? 137.453 127.704 148.556 1.00 278.57 ?  340  ASP B CG  1 
ATOM   5259 O OD1 . ASP B 1 340 ? 136.516 128.111 149.275 1.00 278.57 ?  340  ASP B OD1 1 
ATOM   5260 O OD2 . ASP B 1 340 ? 138.562 128.274 148.495 1.00 278.57 ?  340  ASP B OD2 1 
ATOM   5261 N N   . PHE B 1 341 ? 136.044 128.607 145.583 1.00 303.84 ?  341  PHE B N   1 
ATOM   5262 C CA  . PHE B 1 341 ? 136.172 129.403 144.357 1.00 303.84 ?  341  PHE B CA  1 
ATOM   5263 C C   . PHE B 1 341 ? 137.351 129.221 143.386 1.00 303.84 ?  341  PHE B C   1 
ATOM   5264 O O   . PHE B 1 341 ? 137.124 129.022 142.193 1.00 303.84 ?  341  PHE B O   1 
ATOM   5265 C CB  . PHE B 1 341 ? 135.967 130.900 144.675 1.00 303.84 ?  341  PHE B CB  1 
ATOM   5266 C CG  . PHE B 1 341 ? 135.719 131.188 146.135 1.00 303.84 ?  341  PHE B CG  1 
ATOM   5267 C CD1 . PHE B 1 341 ? 134.431 131.176 146.652 1.00 303.84 ?  341  PHE B CD1 1 
ATOM   5268 C CD2 . PHE B 1 341 ? 136.772 131.491 146.986 1.00 303.84 ?  341  PHE B CD2 1 
ATOM   5269 C CE1 . PHE B 1 341 ? 134.204 131.435 147.989 1.00 303.84 ?  341  PHE B CE1 1 
ATOM   5270 C CE2 . PHE B 1 341 ? 136.550 131.751 148.323 1.00 303.84 ?  341  PHE B CE2 1 
ATOM   5271 C CZ  . PHE B 1 341 ? 135.265 131.727 148.824 1.00 303.84 ?  341  PHE B CZ  1 
ATOM   5272 N N   . PRO B 1 342 ? 138.610 129.285 143.867 1.00 254.20 ?  342  PRO B N   1 
ATOM   5273 C CA  . PRO B 1 342 ? 139.685 129.211 142.864 1.00 254.20 ?  342  PRO B CA  1 
ATOM   5274 C C   . PRO B 1 342 ? 139.946 127.859 142.204 1.00 254.20 ?  342  PRO B C   1 
ATOM   5275 O O   . PRO B 1 342 ? 140.582 127.905 141.152 1.00 254.20 ?  342  PRO B O   1 
ATOM   5276 C CB  . PRO B 1 342 ? 140.932 129.655 143.646 1.00 254.20 ?  342  PRO B CB  1 
ATOM   5277 C CG  . PRO B 1 342 ? 140.424 130.249 144.918 1.00 254.20 ?  342  PRO B CG  1 
ATOM   5278 C CD  . PRO B 1 342 ? 139.173 129.489 145.211 1.00 254.20 ?  342  PRO B CD  1 
ATOM   5279 N N   . PHE B 1 343 ? 139.499 126.737 142.771 1.00 275.51 ?  343  PHE B N   1 
ATOM   5280 C CA  . PHE B 1 343 ? 139.776 125.379 142.247 1.00 275.51 ?  343  PHE B CA  1 
ATOM   5281 C C   . PHE B 1 343 ? 141.228 124.916 142.406 1.00 275.51 ?  343  PHE B C   1 
ATOM   5282 O O   . PHE B 1 343 ? 142.164 125.613 142.024 1.00 275.51 ?  343  PHE B O   1 
ATOM   5283 C CB  . PHE B 1 343 ? 139.258 125.144 140.807 1.00 275.51 ?  343  PHE B CB  1 
ATOM   5284 C CG  . PHE B 1 343 ? 139.793 123.889 140.164 1.00 275.51 ?  343  PHE B CG  1 
ATOM   5285 C CD1 . PHE B 1 343 ? 139.385 122.637 140.604 1.00 275.51 ?  343  PHE B CD1 1 
ATOM   5286 C CD2 . PHE B 1 343 ? 140.712 123.959 139.127 1.00 275.51 ?  343  PHE B CD2 1 
ATOM   5287 C CE1 . PHE B 1 343 ? 139.892 121.487 140.036 1.00 275.51 ?  343  PHE B CE1 1 
ATOM   5288 C CE2 . PHE B 1 343 ? 141.215 122.810 138.549 1.00 275.51 ?  343  PHE B CE2 1 
ATOM   5289 C CZ  . PHE B 1 343 ? 140.807 121.573 139.004 1.00 275.51 ?  343  PHE B CZ  1 
ATOM   5290 N N   . ASP B 1 344 ? 141.417 123.731 142.975 1.00 271.16 ?  344  ASP B N   1 
ATOM   5291 C CA  . ASP B 1 344 ? 142.757 123.193 143.126 1.00 271.16 ?  344  ASP B CA  1 
ATOM   5292 C C   . ASP B 1 344 ? 143.310 122.788 141.783 1.00 271.16 ?  344  ASP B C   1 
ATOM   5293 O O   . ASP B 1 344 ? 142.956 121.746 141.266 1.00 271.16 ?  344  ASP B O   1 
ATOM   5294 C CB  . ASP B 1 344 ? 142.721 121.966 144.021 1.00 271.16 ?  344  ASP B CB  1 
ATOM   5295 C CG  . ASP B 1 344 ? 144.075 121.616 144.581 1.00 271.16 ?  344  ASP B CG  1 
ATOM   5296 O OD1 . ASP B 1 344 ? 144.557 122.330 145.477 1.00 271.16 ?  344  ASP B OD1 1 
ATOM   5297 O OD2 . ASP B 1 344 ? 144.656 120.618 144.129 1.00 271.16 ?  344  ASP B OD2 1 
ATOM   5298 N N   . LEU B 1 345 ? 144.226 123.576 141.239 1.00 247.04 ?  345  LEU B N   1 
ATOM   5299 C CA  . LEU B 1 345 ? 144.813 123.272 139.941 1.00 247.04 ?  345  LEU B CA  1 
ATOM   5300 C C   . LEU B 1 345 ? 145.737 122.067 139.974 1.00 247.04 ?  345  LEU B C   1 
ATOM   5301 O O   . LEU B 1 345 ? 146.231 121.649 138.937 1.00 247.04 ?  345  LEU B O   1 
ATOM   5302 C CB  . LEU B 1 345 ? 145.576 124.478 139.400 1.00 247.04 ?  345  LEU B CB  1 
ATOM   5303 C CG  . LEU B 1 345 ? 144.916 125.404 138.378 1.00 247.04 ?  345  LEU B CG  1 
ATOM   5304 C CD1 . LEU B 1 345 ? 144.337 124.628 137.208 1.00 247.04 ?  345  LEU B CD1 1 
ATOM   5305 C CD2 . LEU B 1 345 ? 143.870 126.309 139.010 1.00 247.04 ?  345  LEU B CD2 1 
ATOM   5306 N N   . LYS B 1 346 ? 146.002 121.520 141.153 1.00 266.65 ?  346  LYS B N   1 
ATOM   5307 C CA  . LYS B 1 346 ? 146.805 120.317 141.237 1.00 266.65 ?  346  LYS B CA  1 
ATOM   5308 C C   . LYS B 1 346 ? 145.920 119.100 141.010 1.00 266.65 ?  346  LYS B C   1 
ATOM   5309 O O   . LYS B 1 346 ? 146.429 118.001 140.810 1.00 266.65 ?  346  LYS B O   1 
ATOM   5310 C CB  . LYS B 1 346 ? 147.512 120.238 142.582 1.00 266.65 ?  346  LYS B CB  1 
ATOM   5311 C CG  . LYS B 1 346 ? 149.003 120.506 142.516 1.00 266.65 ?  346  LYS B CG  1 
ATOM   5312 C CD  . LYS B 1 346 ? 149.740 119.706 143.573 1.00 266.65 ?  346  LYS B CD  1 
ATOM   5313 C CE  . LYS B 1 346 ? 150.545 120.608 144.492 1.00 266.65 ?  346  LYS B CE  1 
ATOM   5314 N NZ  . LYS B 1 346 ? 150.209 120.381 145.925 1.00 266.65 ?  346  LYS B NZ  1 
ATOM   5315 N N   . GLU B 1 347 ? 144.602 119.276 141.055 1.00 288.93 ?  347  GLU B N   1 
ATOM   5316 C CA  . GLU B 1 347 ? 143.694 118.185 140.753 1.00 288.93 ?  347  GLU B CA  1 
ATOM   5317 C C   . GLU B 1 347 ? 143.450 118.166 139.264 1.00 288.93 ?  347  GLU B C   1 
ATOM   5318 O O   . GLU B 1 347 ? 142.983 117.172 138.734 1.00 288.93 ?  347  GLU B O   1 
ATOM   5319 C CB  . GLU B 1 347 ? 142.380 118.366 141.495 1.00 288.93 ?  347  GLU B CB  1 
ATOM   5320 C CG  . GLU B 1 347 ? 142.510 118.322 143.003 1.00 288.93 ?  347  GLU B CG  1 
ATOM   5321 C CD  . GLU B 1 347 ? 141.169 118.357 143.701 1.00 288.93 ?  347  GLU B CD  1 
ATOM   5322 O OE1 . GLU B 1 347 ? 141.140 118.600 144.925 1.00 288.93 ?  347  GLU B OE1 1 
ATOM   5323 O OE2 . GLU B 1 347 ? 140.143 118.141 143.026 1.00 288.93 ?  347  GLU B OE2 1 
ATOM   5324 N N   . LEU B 1 348 ? 143.765 119.261 138.581 1.00 269.76 ?  348  LEU B N   1 
ATOM   5325 C CA  . LEU B 1 348 ? 143.636 119.302 137.123 1.00 269.76 ?  348  LEU B CA  1 
ATOM   5326 C C   . LEU B 1 348 ? 144.359 118.167 136.388 1.00 269.76 ?  348  LEU B C   1 
ATOM   5327 O O   . LEU B 1 348 ? 143.810 117.628 135.444 1.00 269.76 ?  348  LEU B O   1 
ATOM   5328 C CB  . LEU B 1 348 ? 144.012 120.683 136.560 1.00 269.76 ?  348  LEU B CB  1 
ATOM   5329 C CG  . LEU B 1 348 ? 143.243 121.272 135.375 1.00 269.76 ?  348  LEU B CG  1 
ATOM   5330 C CD1 . LEU B 1 348 ? 144.106 121.291 134.125 1.00 269.76 ?  348  LEU B CD1 1 
ATOM   5331 C CD2 . LEU B 1 348 ? 141.925 120.562 135.111 1.00 269.76 ?  348  LEU B CD2 1 
ATOM   5332 N N   . PRO B 1 349 ? 145.599 117.806 136.791 1.00 289.85 ?  349  PRO B N   1 
ATOM   5333 C CA  . PRO B 1 349 ? 146.194 116.640 136.129 1.00 289.85 ?  349  PRO B CA  1 
ATOM   5334 C C   . PRO B 1 349 ? 145.332 115.377 136.194 1.00 289.85 ?  349  PRO B C   1 
ATOM   5335 O O   . PRO B 1 349 ? 145.308 114.633 135.225 1.00 289.85 ?  349  PRO B O   1 
ATOM   5336 C CB  . PRO B 1 349 ? 147.471 116.420 136.926 1.00 289.85 ?  349  PRO B CB  1 
ATOM   5337 C CG  . PRO B 1 349 ? 147.894 117.787 137.301 1.00 289.85 ?  349  PRO B CG  1 
ATOM   5338 C CD  . PRO B 1 349 ? 146.644 118.594 137.481 1.00 289.85 ?  349  PRO B CD  1 
ATOM   5339 N N   . ALA B 1 350 ? 144.643 115.142 137.305 1.00 309.05 ?  350  ALA B N   1 
ATOM   5340 C CA  . ALA B 1 350 ? 143.790 113.969 137.443 1.00 309.05 ?  350  ALA B CA  1 
ATOM   5341 C C   . ALA B 1 350 ? 142.539 114.068 136.602 1.00 309.05 ?  350  ALA B C   1 
ATOM   5342 O O   . ALA B 1 350 ? 142.053 113.065 136.105 1.00 309.05 ?  350  ALA B O   1 
ATOM   5343 C CB  . ALA B 1 350 ? 143.421 113.757 138.891 1.00 309.05 ?  350  ALA B CB  1 
ATOM   5344 N N   . PHE B 1 351 ? 142.008 115.270 136.443 1.00 310.03 ?  351  PHE B N   1 
ATOM   5345 C CA  . PHE B 1 351 ? 140.838 115.465 135.604 1.00 310.03 ?  351  PHE B CA  1 
ATOM   5346 C C   . PHE B 1 351 ? 141.229 115.327 134.150 1.00 310.03 ?  351  PHE B C   1 
ATOM   5347 O O   . PHE B 1 351 ? 140.444 114.860 133.335 1.00 310.03 ?  351  PHE B O   1 
ATOM   5348 C CB  . PHE B 1 351 ? 140.243 116.840 135.851 1.00 310.03 ?  351  PHE B CB  1 
ATOM   5349 C CG  . PHE B 1 351 ? 139.517 116.954 137.149 1.00 310.03 ?  351  PHE B CG  1 
ATOM   5350 C CD1 . PHE B 1 351 ? 138.436 116.150 137.417 1.00 310.03 ?  351  PHE B CD1 1 
ATOM   5351 C CD2 . PHE B 1 351 ? 139.917 117.864 138.100 1.00 310.03 ?  351  PHE B CD2 1 
ATOM   5352 C CE1 . PHE B 1 351 ? 137.756 116.263 138.609 1.00 310.03 ?  351  PHE B CE1 1 
ATOM   5353 C CE2 . PHE B 1 351 ? 139.249 117.970 139.300 1.00 310.03 ?  351  PHE B CE2 1 
ATOM   5354 C CZ  . PHE B 1 351 ? 138.162 117.175 139.552 1.00 310.03 ?  351  PHE B CZ  1 
ATOM   5355 N N   . ALA B 1 352 ? 142.442 115.738 133.816 1.00 330.93 ?  352  ALA B N   1 
ATOM   5356 C CA  . ALA B 1 352 ? 142.922 115.588 132.460 1.00 330.93 ?  352  ALA B CA  1 
ATOM   5357 C C   . ALA B 1 352 ? 143.145 114.119 132.191 1.00 330.93 ?  352  ALA B C   1 
ATOM   5358 O O   . ALA B 1 352 ? 142.893 113.654 131.090 1.00 330.93 ?  352  ALA B O   1 
ATOM   5359 C CB  . ALA B 1 352 ? 144.215 116.354 132.276 1.00 330.93 ?  352  ALA B CB  1 
ATOM   5360 N N   . ALA B 1 353 ? 143.611 113.385 133.197 1.00 337.56 ?  353  ALA B N   1 
ATOM   5361 C CA  . ALA B 1 353 ? 143.832 111.954 133.043 1.00 337.56 ?  353  ALA B CA  1 
ATOM   5362 C C   . ALA B 1 353 ? 142.515 111.245 132.847 1.00 337.56 ?  353  ALA B C   1 
ATOM   5363 O O   . ALA B 1 353 ? 142.441 110.313 132.061 1.00 337.56 ?  353  ALA B O   1 
ATOM   5364 C CB  . ALA B 1 353 ? 144.556 111.394 134.251 1.00 337.56 ?  353  ALA B CB  1 
ATOM   5365 N N   . ILE B 1 354 ? 141.477 111.675 133.557 1.00 316.46 ?  354  ILE B N   1 
ATOM   5366 C CA  . ILE B 1 354 ? 140.156 111.100 133.374 1.00 316.46 ?  354  ILE B CA  1 
ATOM   5367 C C   . ILE B 1 354 ? 139.810 111.239 131.912 1.00 316.46 ?  354  ILE B C   1 
ATOM   5368 O O   . ILE B 1 354 ? 139.492 110.262 131.274 1.00 316.46 ?  354  ILE B O   1 
ATOM   5369 C CB  . ILE B 1 354 ? 139.096 111.815 134.235 1.00 316.46 ?  354  ILE B CB  1 
ATOM   5370 C CG1 . ILE B 1 354 ? 139.172 111.365 135.686 1.00 316.46 ?  354  ILE B CG1 1 
ATOM   5371 C CG2 . ILE B 1 354 ? 137.689 111.557 133.731 1.00 316.46 ?  354  ILE B CG2 1 
ATOM   5372 C CD1 . ILE B 1 354 ? 138.136 112.033 136.558 1.00 316.46 ?  354  ILE B CD1 1 
ATOM   5373 N N   . GLY B 1 355 ? 139.921 112.445 131.366 1.00 313.43 ?  355  GLY B N   1 
ATOM   5374 C CA  . GLY B 1 355 ? 139.621 112.670 129.969 1.00 313.43 ?  355  GLY B CA  1 
ATOM   5375 C C   . GLY B 1 355 ? 140.357 111.766 129.017 1.00 313.43 ?  355  GLY B C   1 
ATOM   5376 O O   . GLY B 1 355 ? 139.741 111.110 128.198 1.00 313.43 ?  355  GLY B O   1 
ATOM   5377 N N   . ILE B 1 356 ? 141.675 111.717 129.122 1.00 339.55 ?  356  ILE B N   1 
ATOM   5378 C CA  . ILE B 1 356 ? 142.469 110.855 128.261 1.00 339.55 ?  356  ILE B CA  1 
ATOM   5379 C C   . ILE B 1 356 ? 141.982 109.422 128.330 1.00 339.55 ?  356  ILE B C   1 
ATOM   5380 O O   . ILE B 1 356 ? 141.693 108.811 127.303 1.00 339.55 ?  356  ILE B O   1 
ATOM   5381 C CB  . ILE B 1 356 ? 143.961 110.911 128.638 1.00 339.55 ?  356  ILE B CB  1 
ATOM   5382 C CG1 . ILE B 1 356 ? 144.487 112.337 128.510 1.00 339.55 ?  356  ILE B CG1 1 
ATOM   5383 C CG2 . ILE B 1 356 ? 144.786 109.986 127.757 1.00 339.55 ?  356  ILE B CG2 1 
ATOM   5384 C CD1 . ILE B 1 356 ? 144.851 112.726 127.096 1.00 339.55 ?  356  ILE B CD1 1 
ATOM   5385 N N   . CYS B 1 357 ? 141.856 108.888 129.538 1.00 342.37 ?  357  CYS B N   1 
ATOM   5386 C CA  . CYS B 1 357 ? 141.428 107.505 129.705 1.00 342.37 ?  357  CYS B CA  1 
ATOM   5387 C C   . CYS B 1 357 ? 139.989 107.260 129.294 1.00 342.37 ?  357  CYS B C   1 
ATOM   5388 O O   . CYS B 1 357 ? 139.673 106.198 128.799 1.00 342.37 ?  357  CYS B O   1 
ATOM   5389 C CB  . CYS B 1 357 ? 141.659 107.049 131.137 1.00 342.37 ?  357  CYS B CB  1 
ATOM   5390 S SG  . CYS B 1 357 ? 143.392 107.020 131.632 1.00 342.37 ?  357  CYS B SG  1 
ATOM   5391 N N   . CYS B 1 358 ? 139.119 108.242 129.474 1.00 330.10 ?  358  CYS B N   1 
ATOM   5392 C CA  . CYS B 1 358 ? 137.731 108.112 129.062 1.00 330.10 ?  358  CYS B CA  1 
ATOM   5393 C C   . CYS B 1 358 ? 137.629 108.141 127.560 1.00 330.10 ?  358  CYS B C   1 
ATOM   5394 O O   . CYS B 1 358 ? 136.699 107.587 127.004 1.00 330.10 ?  358  CYS B O   1 
ATOM   5395 C CB  . CYS B 1 358 ? 136.892 109.236 129.647 1.00 330.10 ?  358  CYS B CB  1 
ATOM   5396 S SG  . CYS B 1 358 ? 136.298 108.957 131.325 1.00 330.10 ?  358  CYS B SG  1 
ATOM   5397 N N   . GLY B 1 359 ? 138.576 108.786 126.892 1.00 335.59 ?  359  GLY B N   1 
ATOM   5398 C CA  . GLY B 1 359 ? 138.598 108.787 125.444 1.00 335.59 ?  359  GLY B CA  1 
ATOM   5399 C C   . GLY B 1 359 ? 139.045 107.441 124.958 1.00 335.59 ?  359  GLY B C   1 
ATOM   5400 O O   . GLY B 1 359 ? 138.524 106.929 123.977 1.00 335.59 ?  359  GLY B O   1 
ATOM   5401 N N   . LEU B 1 360 ? 140.010 106.852 125.646 1.00 355.91 ?  360  LEU B N   1 
ATOM   5402 C CA  . LEU B 1 360 ? 140.455 105.517 125.293 1.00 355.91 ?  360  LEU B CA  1 
ATOM   5403 C C   . LEU B 1 360 ? 139.322 104.537 125.487 1.00 355.91 ?  360  LEU B C   1 
ATOM   5404 O O   . LEU B 1 360 ? 139.029 103.754 124.597 1.00 355.91 ?  360  LEU B O   1 
ATOM   5405 C CB  . LEU B 1 360 ? 141.638 105.105 126.164 1.00 355.91 ?  360  LEU B CB  1 
ATOM   5406 C CG  . LEU B 1 360 ? 142.973 105.780 125.868 1.00 355.91 ?  360  LEU B CG  1 
ATOM   5407 C CD1 . LEU B 1 360 ? 143.842 105.824 127.114 1.00 355.91 ?  360  LEU B CD1 1 
ATOM   5408 C CD2 . LEU B 1 360 ? 143.687 105.053 124.744 1.00 355.91 ?  360  LEU B CD2 1 
ATOM   5409 N N   . LEU B 1 361 ? 138.667 104.591 126.638 1.00 288.30 ?  361  LEU B N   1 
ATOM   5410 C CA  . LEU B 1 361 ? 137.580 103.674 126.934 1.00 288.30 ?  361  LEU B CA  1 
ATOM   5411 C C   . LEU B 1 361 ? 136.348 103.955 126.107 1.00 288.30 ?  361  LEU B C   1 
ATOM   5412 O O   . LEU B 1 361 ? 135.561 103.060 125.853 1.00 288.30 ?  361  LEU B O   1 
ATOM   5413 C CB  . LEU B 1 361 ? 137.240 103.738 128.417 1.00 288.30 ?  361  LEU B CB  1 
ATOM   5414 C CG  . LEU B 1 361 ? 138.283 103.097 129.324 1.00 288.30 ?  361  LEU B CG  1 
ATOM   5415 C CD1 . LEU B 1 361 ? 138.249 103.720 130.710 1.00 288.30 ?  361  LEU B CD1 1 
ATOM   5416 C CD2 . LEU B 1 361 ? 138.084 101.592 129.381 1.00 288.30 ?  361  LEU B CD2 1 
ATOM   5417 N N   . GLY B 1 362 ? 136.172 105.195 125.680 1.00 272.11 ?  362  GLY B N   1 
ATOM   5418 C CA  . GLY B 1 362 ? 135.049 105.539 124.836 1.00 272.11 ?  362  GLY B CA  1 
ATOM   5419 C C   . GLY B 1 362 ? 135.235 104.874 123.507 1.00 272.11 ?  362  GLY B C   1 
ATOM   5420 O O   . GLY B 1 362 ? 134.297 104.323 122.954 1.00 272.11 ?  362  GLY B O   1 
ATOM   5421 N N   . ALA B 1 363 ? 136.457 104.899 122.997 1.00 285.87 ?  363  ALA B N   1 
ATOM   5422 C CA  . ALA B 1 363 ? 136.746 104.237 121.744 1.00 285.87 ?  363  ALA B CA  1 
ATOM   5423 C C   . ALA B 1 363 ? 136.636 102.732 121.892 1.00 285.87 ?  363  ALA B C   1 
ATOM   5424 O O   . ALA B 1 363 ? 136.131 102.070 121.005 1.00 285.87 ?  363  ALA B O   1 
ATOM   5425 C CB  . ALA B 1 363 ? 138.118 104.629 121.258 1.00 285.87 ?  363  ALA B CB  1 
ATOM   5426 N N   . VAL B 1 364 ? 137.090 102.184 123.014 1.00 252.87 ?  364  VAL B N   1 
ATOM   5427 C CA  . VAL B 1 364 ? 136.949 100.749 123.263 1.00 252.87 ?  364  VAL B CA  1 
ATOM   5428 C C   . VAL B 1 364 ? 135.476 100.352 123.264 1.00 252.87 ?  364  VAL B C   1 
ATOM   5429 O O   . VAL B 1 364 ? 135.111 99.362  122.649 1.00 252.87 ?  364  VAL B O   1 
ATOM   5430 C CB  . VAL B 1 364 ? 137.664 100.335 124.568 1.00 252.87 ?  364  VAL B CB  1 
ATOM   5431 C CG1 . VAL B 1 364 ? 137.286 98.928  124.998 1.00 252.87 ?  364  VAL B CG1 1 
ATOM   5432 C CG2 . VAL B 1 364 ? 139.169 100.423 124.391 1.00 252.87 ?  364  VAL B CG2 1 
ATOM   5433 N N   . PHE B 1 365 ? 134.623 101.135 123.915 1.00 248.26 ?  365  PHE B N   1 
ATOM   5434 C CA  . PHE B 1 365 ? 133.195 100.864 123.901 1.00 248.26 ?  365  PHE B CA  1 
ATOM   5435 C C   . PHE B 1 365 ? 132.706 100.812 122.475 1.00 248.26 ?  365  PHE B C   1 
ATOM   5436 O O   . PHE B 1 365 ? 132.121 99.824  122.072 1.00 248.26 ?  365  PHE B O   1 
ATOM   5437 C CB  . PHE B 1 365 ? 132.427 101.945 124.665 1.00 248.26 ?  365  PHE B CB  1 
ATOM   5438 C CG  . PHE B 1 365 ? 131.011 101.569 125.004 1.00 248.26 ?  365  PHE B CG  1 
ATOM   5439 C CD1 . PHE B 1 365 ? 129.977 101.792 124.103 1.00 248.26 ?  365  PHE B CD1 1 
ATOM   5440 C CD2 . PHE B 1 365 ? 130.708 101.010 126.231 1.00 248.26 ?  365  PHE B CD2 1 
ATOM   5441 C CE1 . PHE B 1 365 ? 128.680 101.443 124.412 1.00 248.26 ?  365  PHE B CE1 1 
ATOM   5442 C CE2 . PHE B 1 365 ? 129.412 100.663 126.548 1.00 248.26 ?  365  PHE B CE2 1 
ATOM   5443 C CZ  . PHE B 1 365 ? 128.396 100.882 125.639 1.00 248.26 ?  365  PHE B CZ  1 
ATOM   5444 N N   . VAL B 1 366 ? 132.932 101.879 121.715 1.00 255.93 ?  366  VAL B N   1 
ATOM   5445 C CA  . VAL B 1 366 ? 132.482 101.933 120.327 1.00 255.93 ?  366  VAL B CA  1 
ATOM   5446 C C   . VAL B 1 366 ? 132.963 100.721 119.550 1.00 255.93 ?  366  VAL B C   1 
ATOM   5447 O O   . VAL B 1 366 ? 132.167 100.042 118.909 1.00 255.93 ?  366  VAL B O   1 
ATOM   5448 C CB  . VAL B 1 366 ? 132.935 103.234 119.637 1.00 255.93 ?  366  VAL B CB  1 
ATOM   5449 C CG1 . VAL B 1 366 ? 132.552 103.232 118.172 1.00 255.93 ?  366  VAL B CG1 1 
ATOM   5450 C CG2 . VAL B 1 366 ? 132.312 104.437 120.322 1.00 255.93 ?  366  VAL B CG2 1 
ATOM   5451 N N   . TYR B 1 367 ? 134.252 100.424 119.634 1.00 277.07 ?  367  TYR B N   1 
ATOM   5452 C CA  . TYR B 1 367 ? 134.808 99.271  118.943 1.00 277.07 ?  367  TYR B CA  1 
ATOM   5453 C C   . TYR B 1 367 ? 134.118 97.985  119.325 1.00 277.07 ?  367  TYR B C   1 
ATOM   5454 O O   . TYR B 1 367 ? 133.619 97.281  118.467 1.00 277.07 ?  367  TYR B O   1 
ATOM   5455 C CB  . TYR B 1 367 ? 136.301 99.146  119.236 1.00 277.07 ?  367  TYR B CB  1 
ATOM   5456 C CG  . TYR B 1 367 ? 136.990 98.093  118.411 1.00 277.07 ?  367  TYR B CG  1 
ATOM   5457 C CD1 . TYR B 1 367 ? 137.247 98.302  117.069 1.00 277.07 ?  367  TYR B CD1 1 
ATOM   5458 C CD2 . TYR B 1 367 ? 137.380 96.887  118.974 1.00 277.07 ?  367  TYR B CD2 1 
ATOM   5459 C CE1 . TYR B 1 367 ? 137.874 97.341  116.305 1.00 277.07 ?  367  TYR B CE1 1 
ATOM   5460 C CE2 . TYR B 1 367 ? 138.005 95.919  118.219 1.00 277.07 ?  367  TYR B CE2 1 
ATOM   5461 C CZ  . TYR B 1 367 ? 138.249 96.152  116.885 1.00 277.07 ?  367  TYR B CZ  1 
ATOM   5462 O OH  . TYR B 1 367 ? 138.874 95.193  116.127 1.00 277.07 ?  367  TYR B OH  1 
ATOM   5463 N N   . LEU B 1 368 ? 134.079 97.675  120.609 1.00 258.19 ?  368  LEU B N   1 
ATOM   5464 C CA  . LEU B 1 368 ? 133.503 96.416  121.056 1.00 258.19 ?  368  LEU B CA  1 
ATOM   5465 C C   . LEU B 1 368 ? 132.021 96.302  120.763 1.00 258.19 ?  368  LEU B C   1 
ATOM   5466 O O   . LEU B 1 368 ? 131.531 95.219  120.482 1.00 258.19 ?  368  LEU B O   1 
ATOM   5467 C CB  . LEU B 1 368 ? 133.750 96.237  122.545 1.00 258.19 ?  368  LEU B CB  1 
ATOM   5468 C CG  . LEU B 1 368 ? 134.772 95.201  123.002 1.00 258.19 ?  368  LEU B CG  1 
ATOM   5469 C CD1 . LEU B 1 368 ? 135.868 94.996  121.970 1.00 258.19 ?  368  LEU B CD1 1 
ATOM   5470 C CD2 . LEU B 1 368 ? 135.358 95.616  124.341 1.00 258.19 ?  368  LEU B CD2 1 
ATOM   5471 N N   . HIS B 1 369 ? 131.305 97.414  120.829 1.00 221.21 ?  369  HIS B N   1 
ATOM   5472 C CA  . HIS B 1 369 ? 129.889 97.405  120.536 1.00 221.21 ?  369  HIS B CA  1 
ATOM   5473 C C   . HIS B 1 369 ? 129.690 97.093  119.073 1.00 221.21 ?  369  HIS B C   1 
ATOM   5474 O O   . HIS B 1 369 ? 128.831 96.303  118.724 1.00 221.21 ?  369  HIS B O   1 
ATOM   5475 C CB  . HIS B 1 369 ? 129.265 98.752  120.882 1.00 221.21 ?  369  HIS B CB  1 
ATOM   5476 C CG  . HIS B 1 369 ? 127.890 98.943  120.327 1.00 221.21 ?  369  HIS B CG  1 
ATOM   5477 N ND1 . HIS B 1 369 ? 126.779 98.342  120.873 1.00 221.21 ?  369  HIS B ND1 1 
ATOM   5478 C CD2 . HIS B 1 369 ? 127.448 99.664  119.269 1.00 221.21 ?  369  HIS B CD2 1 
ATOM   5479 C CE1 . HIS B 1 369 ? 125.711 98.686  120.177 1.00 221.21 ?  369  HIS B CE1 1 
ATOM   5480 N NE2 . HIS B 1 369 ? 126.089 99.490  119.201 1.00 221.21 ?  369  HIS B NE2 1 
ATOM   5481 N N   . ARG B 1 370 ? 130.491 97.704  118.210 1.00 225.90 ?  370  ARG B N   1 
ATOM   5482 C CA  . ARG B 1 370 ? 130.388 97.450  116.783 1.00 225.90 ?  370  ARG B CA  1 
ATOM   5483 C C   . ARG B 1 370 ? 130.802 96.023  116.487 1.00 225.90 ?  370  ARG B C   1 
ATOM   5484 O O   . ARG B 1 370 ? 130.222 95.375  115.638 1.00 225.90 ?  370  ARG B O   1 
ATOM   5485 C CB  . ARG B 1 370 ? 131.232 98.455  116.006 1.00 225.90 ?  370  ARG B CB  1 
ATOM   5486 C CG  . ARG B 1 370 ? 131.780 97.984  114.669 1.00 225.90 ?  370  ARG B CG  1 
ATOM   5487 C CD  . ARG B 1 370 ? 132.483 99.113  113.943 1.00 225.90 ?  370  ARG B CD  1 
ATOM   5488 N NE  . ARG B 1 370 ? 132.935 100.135 114.878 1.00 225.90 ?  370  ARG B NE  1 
ATOM   5489 C CZ  . ARG B 1 370 ? 134.204 100.327 115.217 1.00 225.90 ?  370  ARG B CZ  1 
ATOM   5490 N NH1 . ARG B 1 370 ? 135.154 99.567  114.696 1.00 225.90 ?  370  ARG B NH1 1 
ATOM   5491 N NH2 . ARG B 1 370 ? 134.517 101.278 116.078 1.00 225.90 ?  370  ARG B NH2 1 
ATOM   5492 N N   . GLN B 1 371 ? 131.775 95.512  117.222 1.00 244.03 ?  371  GLN B N   1 
ATOM   5493 C CA  . GLN B 1 371 ? 132.230 94.152  117.009 1.00 244.03 ?  371  GLN B CA  1 
ATOM   5494 C C   . GLN B 1 371 ? 131.155 93.140  117.346 1.00 244.03 ?  371  GLN B C   1 
ATOM   5495 O O   . GLN B 1 371 ? 130.983 92.171  116.624 1.00 244.03 ?  371  GLN B O   1 
ATOM   5496 C CB  . GLN B 1 371 ? 133.504 93.874  117.808 1.00 244.03 ?  371  GLN B CB  1 
ATOM   5497 C CG  . GLN B 1 371 ? 134.816 94.057  117.047 1.00 244.03 ?  371  GLN B CG  1 
ATOM   5498 C CD  . GLN B 1 371 ? 134.711 94.937  115.808 1.00 244.03 ?  371  GLN B CD  1 
ATOM   5499 O OE1 . GLN B 1 371 ? 134.671 96.163  115.899 1.00 244.03 ?  371  GLN B OE1 1 
ATOM   5500 N NE2 . GLN B 1 371 ? 134.697 94.307  114.637 1.00 244.03 ?  371  GLN B NE2 1 
ATOM   5501 N N   . VAL B 1 372 ? 130.414 93.360  118.427 1.00 207.35 ?  372  VAL B N   1 
ATOM   5502 C CA  . VAL B 1 372 ? 129.316 92.458  118.757 1.00 207.35 ?  372  VAL B CA  1 
ATOM   5503 C C   . VAL B 1 372 ? 128.116 92.720  117.852 1.00 207.35 ?  372  VAL B C   1 
ATOM   5504 O O   . VAL B 1 372 ? 127.382 91.801  117.518 1.00 207.35 ?  372  VAL B O   1 
ATOM   5505 C CB  . VAL B 1 372 ? 128.980 92.453  120.274 1.00 207.35 ?  372  VAL B CB  1 
ATOM   5506 C CG1 . VAL B 1 372 ? 128.301 93.724  120.721 1.00 207.35 ?  372  VAL B CG1 1 
ATOM   5507 C CG2 . VAL B 1 372 ? 128.152 91.236  120.659 1.00 207.35 ?  372  VAL B CG2 1 
ATOM   5508 N N   . MET B 1 373 ? 127.942 93.956  117.402 1.00 218.54 ?  373  MET B N   1 
ATOM   5509 C CA  . MET B 1 373 ? 126.855 94.269  116.487 1.00 218.54 ?  373  MET B CA  1 
ATOM   5510 C C   . MET B 1 373 ? 127.107 93.562  115.182 1.00 218.54 ?  373  MET B C   1 
ATOM   5511 O O   . MET B 1 373 ? 126.202 92.981  114.617 1.00 218.54 ?  373  MET B O   1 
ATOM   5512 C CB  . MET B 1 373 ? 126.760 95.769  116.236 1.00 218.54 ?  373  MET B CB  1 
ATOM   5513 C CG  . MET B 1 373 ? 125.597 96.453  116.921 1.00 218.54 ?  373  MET B CG  1 
ATOM   5514 S SD  . MET B 1 373 ? 125.133 97.975  116.082 1.00 218.54 ?  373  MET B SD  1 
ATOM   5515 C CE  . MET B 1 373 ? 123.498 98.237  116.764 1.00 218.54 ?  373  MET B CE  1 
ATOM   5516 N N   . LEU B 1 374 ? 128.340 93.616  114.697 1.00 247.46 ?  374  LEU B N   1 
ATOM   5517 C CA  . LEU B 1 374 ? 128.683 92.924  113.473 1.00 247.46 ?  374  LEU B CA  1 
ATOM   5518 C C   . LEU B 1 374 ? 128.573 91.452  113.740 1.00 247.46 ?  374  LEU B C   1 
ATOM   5519 O O   . LEU B 1 374 ? 127.816 90.776  113.077 1.00 247.46 ?  374  LEU B O   1 
ATOM   5520 C CB  . LEU B 1 374 ? 130.101 93.259  113.041 1.00 247.46 ?  374  LEU B CB  1 
ATOM   5521 C CG  . LEU B 1 374 ? 130.271 94.533  112.224 1.00 247.46 ?  374  LEU B CG  1 
ATOM   5522 C CD1 . LEU B 1 374 ? 131.742 94.903  112.139 1.00 247.46 ?  374  LEU B CD1 1 
ATOM   5523 C CD2 . LEU B 1 374 ? 129.673 94.353  110.839 1.00 247.46 ?  374  LEU B CD2 1 
ATOM   5524 N N   . GLY B 1 375 ? 129.314 90.953  114.722 1.00 229.17 ?  375  GLY B N   1 
ATOM   5525 C CA  . GLY B 1 375 ? 129.280 89.543  115.075 1.00 229.17 ?  375  GLY B CA  1 
ATOM   5526 C C   . GLY B 1 375 ? 127.948 88.832  114.971 1.00 229.17 ?  375  GLY B C   1 
ATOM   5527 O O   . GLY B 1 375 ? 127.852 87.805  114.310 1.00 229.17 ?  375  GLY B O   1 
ATOM   5528 N N   . VAL B 1 376 ? 126.911 89.373  115.601 1.00 228.87 ?  376  VAL B N   1 
ATOM   5529 C CA  . VAL B 1 376 ? 125.607 88.719  115.585 1.00 228.87 ?  376  VAL B CA  1 
ATOM   5530 C C   . VAL B 1 376 ? 124.978 88.577  114.197 1.00 228.87 ?  376  VAL B C   1 
ATOM   5531 O O   . VAL B 1 376 ? 124.128 87.717  114.008 1.00 228.87 ?  376  VAL B O   1 
ATOM   5532 C CB  . VAL B 1 376 ? 124.608 89.346  116.584 1.00 228.87 ?  376  VAL B CB  1 
ATOM   5533 C CG1 . VAL B 1 376 ? 125.139 89.239  118.004 1.00 228.87 ?  376  VAL B CG1 1 
ATOM   5534 C CG2 . VAL B 1 376 ? 124.275 90.781  116.226 1.00 228.87 ?  376  VAL B CG2 1 
ATOM   5535 N N   . ARG B 1 377 ? 125.404 89.391  113.235 1.00 232.24 ?  377  ARG B N   1 
ATOM   5536 C CA  . ARG B 1 377 ? 124.875 89.297  111.873 1.00 232.24 ?  377  ARG B CA  1 
ATOM   5537 C C   . ARG B 1 377 ? 125.899 88.795  110.851 1.00 232.24 ?  377  ARG B C   1 
ATOM   5538 O O   . ARG B 1 377 ? 125.545 88.067  109.926 1.00 232.24 ?  377  ARG B O   1 
ATOM   5539 C CB  . ARG B 1 377 ? 124.254 90.630  111.429 1.00 232.24 ?  377  ARG B CB  1 
ATOM   5540 C CG  . ARG B 1 377 ? 125.230 91.778  111.243 1.00 232.24 ?  377  ARG B CG  1 
ATOM   5541 C CD  . ARG B 1 377 ? 124.577 93.107  111.576 1.00 232.24 ?  377  ARG B CD  1 
ATOM   5542 N NE  . ARG B 1 377 ? 123.500 92.952  112.549 1.00 232.24 ?  377  ARG B NE  1 
ATOM   5543 C CZ  . ARG B 1 377 ? 123.200 93.852  113.479 1.00 232.24 ?  377  ARG B CZ  1 
ATOM   5544 N NH1 . ARG B 1 377 ? 123.899 94.975  113.565 1.00 232.24 ?  377  ARG B NH1 1 
ATOM   5545 N NH2 . ARG B 1 377 ? 122.203 93.630  114.323 1.00 232.24 ?  377  ARG B NH2 1 
ATOM   5546 N N   . LYS B 1 378 ? 127.161 89.170  111.015 1.00 222.40 ?  378  LYS B N   1 
ATOM   5547 C CA  . LYS B 1 378 ? 128.204 88.753  110.082 1.00 222.40 ?  378  LYS B CA  1 
ATOM   5548 C C   . LYS B 1 378 ? 128.523 87.273  110.211 1.00 222.40 ?  378  LYS B C   1 
ATOM   5549 O O   . LYS B 1 378 ? 128.893 86.635  109.226 1.00 222.40 ?  378  LYS B O   1 
ATOM   5550 C CB  . LYS B 1 378 ? 129.459 89.639  110.183 1.00 222.40 ?  378  LYS B CB  1 
ATOM   5551 C CG  . LYS B 1 378 ? 130.388 89.352  111.354 1.00 222.40 ?  378  LYS B CG  1 
ATOM   5552 C CD  . LYS B 1 378 ? 131.766 88.916  110.892 1.00 222.40 ?  378  LYS B CD  1 
ATOM   5553 C CE  . LYS B 1 378 ? 132.233 87.704  111.678 1.00 222.40 ?  378  LYS B CE  1 
ATOM   5554 N NZ  . LYS B 1 378 ? 131.456 87.544  112.936 1.00 222.40 ?  378  LYS B NZ  1 
ATOM   5555 N N   . HIS B 1 379 ? 128.381 86.711  111.405 1.00 220.23 ?  379  HIS B N   1 
ATOM   5556 C CA  . HIS B 1 379 ? 128.572 85.281  111.547 1.00 220.23 ?  379  HIS B CA  1 
ATOM   5557 C C   . HIS B 1 379 ? 127.287 84.687  111.021 1.00 220.23 ?  379  HIS B C   1 
ATOM   5558 O O   . HIS B 1 379 ? 126.223 84.926  111.585 1.00 220.23 ?  379  HIS B O   1 
ATOM   5559 C CB  . HIS B 1 379 ? 128.788 84.904  113.005 1.00 220.23 ?  379  HIS B CB  1 
ATOM   5560 C CG  . HIS B 1 379 ? 129.008 83.442  113.228 1.00 220.23 ?  379  HIS B CG  1 
ATOM   5561 N ND1 . HIS B 1 379 ? 128.683 82.816  114.411 1.00 220.23 ?  379  HIS B ND1 1 
ATOM   5562 C CD2 . HIS B 1 379 ? 129.528 82.484  112.425 1.00 220.23 ?  379  HIS B CD2 1 
ATOM   5563 C CE1 . HIS B 1 379 ? 128.990 81.534  114.328 1.00 220.23 ?  379  HIS B CE1 1 
ATOM   5564 N NE2 . HIS B 1 379 ? 129.504 81.306  113.132 1.00 220.23 ?  379  HIS B NE2 1 
ATOM   5565 N N   . LYS B 1 380 ? 127.372 83.929  109.935 1.00 238.70 ?  380  LYS B N   1 
ATOM   5566 C CA  . LYS B 1 380 ? 126.168 83.385  109.320 1.00 238.70 ?  380  LYS B CA  1 
ATOM   5567 C C   . LYS B 1 380 ? 125.349 82.510  110.258 1.00 238.70 ?  380  LYS B C   1 
ATOM   5568 O O   . LYS B 1 380 ? 124.136 82.666  110.345 1.00 238.70 ?  380  LYS B O   1 
ATOM   5569 C CB  . LYS B 1 380 ? 126.506 82.623  108.040 1.00 238.70 ?  380  LYS B CB  1 
ATOM   5570 C CG  . LYS B 1 380 ? 125.562 82.919  106.884 1.00 238.70 ?  380  LYS B CG  1 
ATOM   5571 C CD  . LYS B 1 380 ? 124.872 84.265  107.049 1.00 238.70 ?  380  LYS B CD  1 
ATOM   5572 C CE  . LYS B 1 380 ? 123.379 84.163  106.773 1.00 238.70 ?  380  LYS B CE  1 
ATOM   5573 N NZ  . LYS B 1 380 ? 122.596 83.877  108.007 1.00 238.70 ?  380  LYS B NZ  1 
ATOM   5574 N N   . ALA B 1 381 ? 126.008 81.600  110.966 1.00 240.43 ?  381  ALA B N   1 
ATOM   5575 C CA  . ALA B 1 381 ? 125.301 80.748  111.913 1.00 240.43 ?  381  ALA B CA  1 
ATOM   5576 C C   . ALA B 1 381 ? 124.555 81.585  112.935 1.00 240.43 ?  381  ALA B C   1 
ATOM   5577 O O   . ALA B 1 381 ? 123.381 81.340  113.196 1.00 240.43 ?  381  ALA B O   1 
ATOM   5578 C CB  . ALA B 1 381 ? 126.264 79.802  112.605 1.00 240.43 ?  381  ALA B CB  1 
ATOM   5579 N N   . LEU B 1 382 ? 125.230 82.580  113.503 1.00 228.50 ?  382  LEU B N   1 
ATOM   5580 C CA  . LEU B 1 382 ? 124.597 83.437  114.494 1.00 228.50 ?  382  LEU B CA  1 
ATOM   5581 C C   . LEU B 1 382 ? 123.344 84.093  113.951 1.00 228.50 ?  382  LEU B C   1 
ATOM   5582 O O   . LEU B 1 382 ? 122.282 83.988  114.556 1.00 228.50 ?  382  LEU B O   1 
ATOM   5583 C CB  . LEU B 1 382 ? 125.563 84.514  114.968 1.00 228.50 ?  382  LEU B CB  1 
ATOM   5584 C CG  . LEU B 1 382 ? 125.645 84.717  116.477 1.00 228.50 ?  382  LEU B CG  1 
ATOM   5585 C CD1 . LEU B 1 382 ? 125.272 83.435  117.204 1.00 228.50 ?  382  LEU B CD1 1 
ATOM   5586 C CD2 . LEU B 1 382 ? 127.036 85.181  116.876 1.00 228.50 ?  382  LEU B CD2 1 
ATOM   5587 N N   . SER B 1 383 ? 123.456 84.769  112.814 1.00 247.68 ?  383  SER B N   1 
ATOM   5588 C CA  . SER B 1 383 ? 122.307 85.482  112.274 1.00 247.68 ?  383  SER B CA  1 
ATOM   5589 C C   . SER B 1 383 ? 121.154 84.544  112.003 1.00 247.68 ?  383  SER B C   1 
ATOM   5590 O O   . SER B 1 383 ? 120.032 84.826  112.399 1.00 247.68 ?  383  SER B O   1 
ATOM   5591 C CB  . SER B 1 383 ? 122.672 86.238  111.003 1.00 247.68 ?  383  SER B CB  1 
ATOM   5592 O OG  . SER B 1 383 ? 123.754 85.624  110.337 1.00 247.68 ?  383  SER B OG  1 
ATOM   5593 N N   . GLN B 1 384 ? 121.428 83.426  111.340 1.00 260.88 ?  384  GLN B N   1 
ATOM   5594 C CA  . GLN B 1 384 ? 120.386 82.455  111.033 1.00 260.88 ?  384  GLN B CA  1 
ATOM   5595 C C   . GLN B 1 384 ? 119.675 82.011  112.302 1.00 260.88 ?  384  GLN B C   1 
ATOM   5596 O O   . GLN B 1 384 ? 118.449 82.052  112.373 1.00 260.88 ?  384  GLN B O   1 
ATOM   5597 C CB  . GLN B 1 384 ? 121.003 81.259  110.300 1.00 260.88 ?  384  GLN B CB  1 
ATOM   5598 C CG  . GLN B 1 384 ? 120.138 80.012  110.234 1.00 260.88 ?  384  GLN B CG  1 
ATOM   5599 C CD  . GLN B 1 384 ? 120.737 78.852  111.007 1.00 260.88 ?  384  GLN B CD  1 
ATOM   5600 O OE1 . GLN B 1 384 ? 120.170 77.762  111.048 1.00 260.88 ?  384  GLN B OE1 1 
ATOM   5601 N NE2 . GLN B 1 384 ? 121.888 79.083  111.628 1.00 260.88 ?  384  GLN B NE2 1 
ATOM   5602 N N   . PHE B 1 385 ? 120.439 81.611  113.312 1.00 248.33 ?  385  PHE B N   1 
ATOM   5603 C CA  . PHE B 1 385 ? 119.857 81.168  114.571 1.00 248.33 ?  385  PHE B CA  1 
ATOM   5604 C C   . PHE B 1 385 ? 118.959 82.227  115.168 1.00 248.33 ?  385  PHE B C   1 
ATOM   5605 O O   . PHE B 1 385 ? 117.813 81.955  115.511 1.00 248.33 ?  385  PHE B O   1 
ATOM   5606 C CB  . PHE B 1 385 ? 120.976 80.857  115.558 1.00 248.33 ?  385  PHE B CB  1 
ATOM   5607 C CG  . PHE B 1 385 ? 120.563 79.970  116.689 1.00 248.33 ?  385  PHE B CG  1 
ATOM   5608 C CD1 . PHE B 1 385 ? 120.347 78.621  116.481 1.00 248.33 ?  385  PHE B CD1 1 
ATOM   5609 C CD2 . PHE B 1 385 ? 120.404 80.482  117.965 1.00 248.33 ?  385  PHE B CD2 1 
ATOM   5610 C CE1 . PHE B 1 385 ? 119.973 77.797  117.523 1.00 248.33 ?  385  PHE B CE1 1 
ATOM   5611 C CE2 . PHE B 1 385 ? 120.029 79.665  119.011 1.00 248.33 ?  385  PHE B CE2 1 
ATOM   5612 C CZ  . PHE B 1 385 ? 119.813 78.319  118.791 1.00 248.33 ?  385  PHE B CZ  1 
ATOM   5613 N N   . LEU B 1 386 ? 119.464 83.446  115.278 1.00 263.65 ?  386  LEU B N   1 
ATOM   5614 C CA  . LEU B 1 386 ? 118.701 84.510  115.916 1.00 263.65 ?  386  LEU B CA  1 
ATOM   5615 C C   . LEU B 1 386 ? 117.557 85.047  115.065 1.00 263.65 ?  386  LEU B C   1 
ATOM   5616 O O   . LEU B 1 386 ? 116.738 85.818  115.549 1.00 263.65 ?  386  LEU B O   1 
ATOM   5617 C CB  . LEU B 1 386 ? 119.635 85.654  116.306 1.00 263.65 ?  386  LEU B CB  1 
ATOM   5618 C CG  . LEU B 1 386 ? 120.375 85.617  117.646 1.00 263.65 ?  386  LEU B CG  1 
ATOM   5619 C CD1 . LEU B 1 386 ? 120.161 84.336  118.439 1.00 263.65 ?  386  LEU B CD1 1 
ATOM   5620 C CD2 . LEU B 1 386 ? 121.855 85.916  117.470 1.00 263.65 ?  386  LEU B CD2 1 
ATOM   5621 N N   . ALA B 1 387 ? 117.499 84.667  113.796 1.00 306.87 ?  387  ALA B N   1 
ATOM   5622 C CA  . ALA B 1 387 ? 116.386 85.087  112.960 1.00 306.87 ?  387  ALA B CA  1 
ATOM   5623 C C   . ALA B 1 387 ? 115.280 84.070  113.103 1.00 306.87 ?  387  ALA B C   1 
ATOM   5624 O O   . ALA B 1 387 ? 114.102 84.410  113.015 1.00 306.87 ?  387  ALA B O   1 
ATOM   5625 C CB  . ALA B 1 387 ? 116.813 85.211  111.510 1.00 306.87 ?  387  ALA B CB  1 
ATOM   5626 N N   . LYS B 1 388 ? 115.652 82.815  113.323 1.00 268.22 ?  388  LYS B N   1 
ATOM   5627 C CA  . LYS B 1 388 ? 114.651 81.787  113.537 1.00 268.22 ?  388  LYS B CA  1 
ATOM   5628 C C   . LYS B 1 388 ? 114.029 82.028  114.892 1.00 268.22 ?  388  LYS B C   1 
ATOM   5629 O O   . LYS B 1 388 ? 112.807 82.077  115.021 1.00 268.22 ?  388  LYS B O   1 
ATOM   5630 C CB  . LYS B 1 388 ? 115.290 80.405  113.487 1.00 268.22 ?  388  LYS B CB  1 
ATOM   5631 C CG  . LYS B 1 388 ? 115.648 79.948  112.085 1.00 268.22 ?  388  LYS B CG  1 
ATOM   5632 C CD  . LYS B 1 388 ? 116.782 78.937  112.110 1.00 268.22 ?  388  LYS B CD  1 
ATOM   5633 C CE  . LYS B 1 388 ? 117.178 78.601  113.536 1.00 268.22 ?  388  LYS B CE  1 
ATOM   5634 N NZ  . LYS B 1 388 ? 118.460 77.851  113.606 1.00 268.22 ?  388  LYS B NZ  1 
ATOM   5635 N N   . HIS B 1 389 ? 114.864 82.184  115.909 1.00 274.50 ?  389  HIS B N   1 
ATOM   5636 C CA  . HIS B 1 389 ? 114.355 82.489  117.235 1.00 274.50 ?  389  HIS B CA  1 
ATOM   5637 C C   . HIS B 1 389 ? 114.659 83.939  117.530 1.00 274.50 ?  389  HIS B C   1 
ATOM   5638 O O   . HIS B 1 389 ? 115.738 84.261  118.013 1.00 274.50 ?  389  HIS B O   1 
ATOM   5639 C CB  . HIS B 1 389 ? 115.002 81.589  118.275 1.00 274.50 ?  389  HIS B CB  1 
ATOM   5640 C CG  . HIS B 1 389 ? 115.458 80.273  117.730 1.00 274.50 ?  389  HIS B CG  1 
ATOM   5641 N ND1 . HIS B 1 389 ? 114.583 79.311  117.276 1.00 274.50 ?  389  HIS B ND1 1 
ATOM   5642 C CD2 . HIS B 1 389 ? 116.700 79.760  117.565 1.00 274.50 ?  389  HIS B CD2 1 
ATOM   5643 C CE1 . HIS B 1 389 ? 115.266 78.262  116.854 1.00 274.50 ?  389  HIS B CE1 1 
ATOM   5644 N NE2 . HIS B 1 389 ? 116.553 78.510  117.019 1.00 274.50 ?  389  HIS B NE2 1 
ATOM   5645 N N   . ARG B 1 390 ? 113.711 84.818  117.240 1.00 261.05 ?  390  ARG B N   1 
ATOM   5646 C CA  . ARG B 1 390 ? 113.933 86.247  117.431 1.00 261.05 ?  390  ARG B CA  1 
ATOM   5647 C C   . ARG B 1 390 ? 114.193 86.640  118.871 1.00 261.05 ?  390  ARG B C   1 
ATOM   5648 O O   . ARG B 1 390 ? 115.073 87.452  119.134 1.00 261.05 ?  390  ARG B O   1 
ATOM   5649 C CB  . ARG B 1 390 ? 112.737 87.037  116.904 1.00 261.05 ?  390  ARG B CB  1 
ATOM   5650 C CG  . ARG B 1 390 ? 112.467 86.823  115.429 1.00 261.05 ?  390  ARG B CG  1 
ATOM   5651 C CD  . ARG B 1 390 ? 113.364 87.709  114.589 1.00 261.05 ?  390  ARG B CD  1 
ATOM   5652 N NE  . ARG B 1 390 ? 113.147 87.496  113.165 1.00 261.05 ?  390  ARG B NE  1 
ATOM   5653 C CZ  . ARG B 1 390 ? 113.968 87.928  112.216 1.00 261.05 ?  390  ARG B CZ  1 
ATOM   5654 N NH1 . ARG B 1 390 ? 115.067 88.593  112.543 1.00 261.05 ?  390  ARG B NH1 1 
ATOM   5655 N NH2 . ARG B 1 390 ? 113.696 87.689  110.941 1.00 261.05 ?  390  ARG B NH2 1 
ATOM   5656 N N   . LEU B 1 391 ? 113.447 86.065  119.807 1.00 317.49 ?  391  LEU B N   1 
ATOM   5657 C CA  . LEU B 1 391 ? 113.581 86.450  121.209 1.00 317.49 ?  391  LEU B CA  1 
ATOM   5658 C C   . LEU B 1 391 ? 114.684 85.718  121.960 1.00 317.49 ?  391  LEU B C   1 
ATOM   5659 O O   . LEU B 1 391 ? 114.754 85.795  123.181 1.00 317.49 ?  391  LEU B O   1 
ATOM   5660 C CB  . LEU B 1 391 ? 112.249 86.266  121.934 1.00 317.49 ?  391  LEU B CB  1 
ATOM   5661 C CG  . LEU B 1 391 ? 111.067 87.093  121.428 1.00 317.49 ?  391  LEU B CG  1 
ATOM   5662 C CD1 . LEU B 1 391 ? 109.837 86.833  122.280 1.00 317.49 ?  391  LEU B CD1 1 
ATOM   5663 C CD2 . LEU B 1 391 ? 111.403 88.573  121.419 1.00 317.49 ?  391  LEU B CD2 1 
ATOM   5664 N N   . LEU B 1 392 ? 115.548 85.015  121.239 1.00 322.38 ?  392  LEU B N   1 
ATOM   5665 C CA  . LEU B 1 392 ? 116.656 84.322  121.876 1.00 322.38 ?  392  LEU B CA  1 
ATOM   5666 C C   . LEU B 1 392 ? 117.682 85.326  122.355 1.00 322.38 ?  392  LEU B C   1 
ATOM   5667 O O   . LEU B 1 392 ? 117.956 85.402  123.540 1.00 322.38 ?  392  LEU B O   1 
ATOM   5668 C CB  . LEU B 1 392 ? 117.310 83.341  120.910 1.00 322.38 ?  392  LEU B CB  1 
ATOM   5669 C CG  . LEU B 1 392 ? 117.429 81.891  121.372 1.00 322.38 ?  392  LEU B CG  1 
ATOM   5670 C CD1 . LEU B 1 392 ? 118.758 81.658  122.070 1.00 322.38 ?  392  LEU B CD1 1 
ATOM   5671 C CD2 . LEU B 1 392 ? 116.269 81.529  122.283 1.00 322.38 ?  392  LEU B CD2 1 
ATOM   5672 N N   . TYR B 1 393 ? 118.245 86.098  121.434 1.00 284.68 ?  393  TYR B N   1 
ATOM   5673 C CA  . TYR B 1 393 ? 119.245 87.097  121.803 1.00 284.68 ?  393  TYR B CA  1 
ATOM   5674 C C   . TYR B 1 393 ? 118.827 88.030  122.938 1.00 284.68 ?  393  TYR B C   1 
ATOM   5675 O O   . TYR B 1 393 ? 119.522 88.094  123.944 1.00 284.68 ?  393  TYR B O   1 
ATOM   5676 C CB  . TYR B 1 393 ? 119.771 87.879  120.587 1.00 284.68 ?  393  TYR B CB  1 
ATOM   5677 C CG  . TYR B 1 393 ? 120.978 88.736  120.885 1.00 284.68 ?  393  TYR B CG  1 
ATOM   5678 C CD1 . TYR B 1 393 ? 122.216 88.161  121.119 1.00 284.68 ?  393  TYR B CD1 1 
ATOM   5679 C CD2 . TYR B 1 393 ? 120.879 90.120  120.931 1.00 284.68 ?  393  TYR B CD2 1 
ATOM   5680 C CE1 . TYR B 1 393 ? 123.323 88.939  121.391 1.00 284.68 ?  393  TYR B CE1 1 
ATOM   5681 C CE2 . TYR B 1 393 ? 121.981 90.906  121.205 1.00 284.68 ?  393  TYR B CE2 1 
ATOM   5682 C CZ  . TYR B 1 393 ? 123.200 90.311  121.432 1.00 284.68 ?  393  TYR B CZ  1 
ATOM   5683 O OH  . TYR B 1 393 ? 124.301 91.086  121.707 1.00 284.68 ?  393  TYR B OH  1 
ATOM   5684 N N   . PRO B 1 394 ? 117.694 88.755  122.798 1.00 278.97 ?  394  PRO B N   1 
ATOM   5685 C CA  . PRO B 1 394 ? 117.390 89.618  123.943 1.00 278.97 ?  394  PRO B CA  1 
ATOM   5686 C C   . PRO B 1 394 ? 117.216 88.825  125.222 1.00 278.97 ?  394  PRO B C   1 
ATOM   5687 O O   . PRO B 1 394 ? 117.737 89.240  126.242 1.00 278.97 ?  394  PRO B O   1 
ATOM   5688 C CB  . PRO B 1 394 ? 116.082 90.312  123.540 1.00 278.97 ?  394  PRO B CB  1 
ATOM   5689 C CG  . PRO B 1 394 ? 115.524 89.512  122.425 1.00 278.97 ?  394  PRO B CG  1 
ATOM   5690 C CD  . PRO B 1 394 ? 116.703 88.930  121.719 1.00 278.97 ?  394  PRO B CD  1 
ATOM   5691 N N   . GLY B 1 395 ? 116.531 87.691  125.166 1.00 324.54 ?  395  GLY B N   1 
ATOM   5692 C CA  . GLY B 1 395 ? 116.333 86.859  126.332 1.00 324.54 ?  395  GLY B CA  1 
ATOM   5693 C C   . GLY B 1 395 ? 117.605 86.470  127.041 1.00 324.54 ?  395  GLY B C   1 
ATOM   5694 O O   . GLY B 1 395 ? 117.749 86.724  128.229 1.00 324.54 ?  395  GLY B O   1 
ATOM   5695 N N   . ILE B 1 396 ? 118.537 85.861  126.323 1.00 365.59 ?  396  ILE B N   1 
ATOM   5696 C CA  . ILE B 1 396 ? 119.759 85.404  126.958 1.00 365.59 ?  396  ILE B CA  1 
ATOM   5697 C C   . ILE B 1 396 ? 120.595 86.560  127.492 1.00 365.59 ?  396  ILE B C   1 
ATOM   5698 O O   . ILE B 1 396 ? 121.155 86.458  128.572 1.00 365.59 ?  396  ILE B O   1 
ATOM   5699 C CB  . ILE B 1 396 ? 120.588 84.450  126.062 1.00 365.59 ?  396  ILE B CB  1 
ATOM   5700 C CG1 . ILE B 1 396 ? 121.112 85.150  124.805 1.00 365.59 ?  396  ILE B CG1 1 
ATOM   5701 C CG2 . ILE B 1 396 ? 119.762 83.233  125.683 1.00 365.59 ?  396  ILE B CG2 1 
ATOM   5702 C CD1 . ILE B 1 396 ? 121.488 84.209  123.685 1.00 365.59 ?  396  ILE B CD1 1 
ATOM   5703 N N   . VAL B 1 397 ? 120.648 87.671  126.766 1.00 328.67 ?  397  VAL B N   1 
ATOM   5704 C CA  . VAL B 1 397 ? 121.419 88.817  127.210 1.00 328.67 ?  397  VAL B CA  1 
ATOM   5705 C C   . VAL B 1 397 ? 120.818 89.363  128.495 1.00 328.67 ?  397  VAL B C   1 
ATOM   5706 O O   . VAL B 1 397 ? 121.518 89.529  129.483 1.00 328.67 ?  397  VAL B O   1 
ATOM   5707 C CB  . VAL B 1 397 ? 121.521 89.896  126.114 1.00 328.67 ?  397  VAL B CB  1 
ATOM   5708 C CG1 . VAL B 1 397 ? 121.991 91.218  126.686 1.00 328.67 ?  397  VAL B CG1 1 
ATOM   5709 C CG2 . VAL B 1 397 ? 122.479 89.440  125.032 1.00 328.67 ?  397  VAL B CG2 1 
ATOM   5710 N N   . THR B 1 398 ? 119.512 89.590  128.505 1.00 299.27 ?  398  THR B N   1 
ATOM   5711 C CA  . THR B 1 398 ? 118.850 90.071  129.706 1.00 299.27 ?  398  THR B CA  1 
ATOM   5712 C C   . THR B 1 398 ? 119.088 89.143  130.876 1.00 299.27 ?  398  THR B C   1 
ATOM   5713 O O   . THR B 1 398 ? 119.471 89.590  131.950 1.00 299.27 ?  398  THR B O   1 
ATOM   5714 C CB  . THR B 1 398 ? 117.347 90.209  129.485 1.00 299.27 ?  398  THR B CB  1 
ATOM   5715 O OG1 . THR B 1 398 ? 117.122 90.953  128.288 1.00 299.27 ?  398  THR B OG1 1 
ATOM   5716 C CG2 . THR B 1 398 ? 116.720 90.938  130.626 1.00 299.27 ?  398  THR B CG2 1 
ATOM   5717 N N   . PHE B 1 399 ? 118.882 87.849  130.669 1.00 309.78 ?  399  PHE B N   1 
ATOM   5718 C CA  . PHE B 1 399 ? 119.100 86.886  131.731 1.00 309.78 ?  399  PHE B CA  1 
ATOM   5719 C C   . PHE B 1 399 ? 120.495 87.000  132.318 1.00 309.78 ?  399  PHE B C   1 
ATOM   5720 O O   . PHE B 1 399 ? 120.632 87.124  133.522 1.00 309.78 ?  399  PHE B O   1 
ATOM   5721 C CB  . PHE B 1 399 ? 118.849 85.458  131.254 1.00 309.78 ?  399  PHE B CB  1 
ATOM   5722 C CG  . PHE B 1 399 ? 119.083 84.424  132.314 1.00 309.78 ?  399  PHE B CG  1 
ATOM   5723 C CD1 . PHE B 1 399 ? 118.218 84.313  133.387 1.00 309.78 ?  399  PHE B CD1 1 
ATOM   5724 C CD2 . PHE B 1 399 ? 120.176 83.578  132.250 1.00 309.78 ?  399  PHE B CD2 1 
ATOM   5725 C CE1 . PHE B 1 399 ? 118.434 83.373  134.373 1.00 309.78 ?  399  PHE B CE1 1 
ATOM   5726 C CE2 . PHE B 1 399 ? 120.400 82.638  133.235 1.00 309.78 ?  399  PHE B CE2 1 
ATOM   5727 C CZ  . PHE B 1 399 ? 119.525 82.534  134.297 1.00 309.78 ?  399  PHE B CZ  1 
ATOM   5728 N N   . VAL B 1 400 ? 121.531 86.959  131.486 1.00 287.95 ?  400  VAL B N   1 
ATOM   5729 C CA  . VAL B 1 400 ? 122.885 86.986  132.025 1.00 287.95 ?  400  VAL B CA  1 
ATOM   5730 C C   . VAL B 1 400 ? 123.245 88.308  132.695 1.00 287.95 ?  400  VAL B C   1 
ATOM   5731 O O   . VAL B 1 400 ? 123.948 88.309  133.696 1.00 287.95 ?  400  VAL B O   1 
ATOM   5732 C CB  . VAL B 1 400 ? 123.970 86.526  131.017 1.00 287.95 ?  400  VAL B CB  1 
ATOM   5733 C CG1 . VAL B 1 400 ? 123.643 85.145  130.476 1.00 287.95 ?  400  VAL B CG1 1 
ATOM   5734 C CG2 . VAL B 1 400 ? 124.192 87.525  129.895 1.00 287.95 ?  400  VAL B CG2 1 
ATOM   5735 N N   . ILE B 1 401 ? 122.742 89.427  132.184 1.00 229.00 ?  401  ILE B N   1 
ATOM   5736 C CA  . ILE B 1 401 ? 122.992 90.706  132.828 1.00 229.00 ?  401  ILE B CA  1 
ATOM   5737 C C   . ILE B 1 401 ? 122.350 90.674  134.201 1.00 229.00 ?  401  ILE B C   1 
ATOM   5738 O O   . ILE B 1 401 ? 122.995 90.978  135.196 1.00 229.00 ?  401  ILE B O   1 
ATOM   5739 C CB  . ILE B 1 401 ? 122.437 91.885  131.999 1.00 229.00 ?  401  ILE B CB  1 
ATOM   5740 C CG1 . ILE B 1 401 ? 123.237 92.056  130.713 1.00 229.00 ?  401  ILE B CG1 1 
ATOM   5741 C CG2 . ILE B 1 401 ? 122.464 93.183  132.789 1.00 229.00 ?  401  ILE B CG2 1 
ATOM   5742 C CD1 . ILE B 1 401 ? 122.757 93.213  129.871 1.00 229.00 ?  401  ILE B CD1 1 
ATOM   5743 N N   . ALA B 1 402 ? 121.092 90.256  134.268 1.00 255.59 ?  402  ALA B N   1 
ATOM   5744 C CA  . ALA B 1 402 ? 120.381 90.235  135.534 1.00 255.59 ?  402  ALA B CA  1 
ATOM   5745 C C   . ALA B 1 402 ? 120.909 89.195  136.511 1.00 255.59 ?  402  ALA B C   1 
ATOM   5746 O O   . ALA B 1 402 ? 120.809 89.371  137.715 1.00 255.59 ?  402  ALA B O   1 
ATOM   5747 C CB  . ALA B 1 402 ? 118.899 90.054  135.297 1.00 255.59 ?  402  ALA B CB  1 
ATOM   5748 N N   . SER B 1 403 ? 121.493 88.121  136.006 1.00 271.02 ?  403  SER B N   1 
ATOM   5749 C CA  . SER B 1 403 ? 122.048 87.097  136.873 1.00 271.02 ?  403  SER B CA  1 
ATOM   5750 C C   . SER B 1 403 ? 123.361 87.560  137.469 1.00 271.02 ?  403  SER B C   1 
ATOM   5751 O O   . SER B 1 403 ? 123.747 87.121  138.549 1.00 271.02 ?  403  SER B O   1 
ATOM   5752 C CB  . SER B 1 403 ? 122.245 85.796  136.101 1.00 271.02 ?  403  SER B CB  1 
ATOM   5753 O OG  . SER B 1 403 ? 123.436 85.832  135.339 1.00 271.02 ?  403  SER B OG  1 
ATOM   5754 N N   . PHE B 1 404 ? 124.055 88.450  136.773 1.00 221.39 ?  404  PHE B N   1 
ATOM   5755 C CA  . PHE B 1 404 ? 125.303 88.984  137.288 1.00 221.39 ?  404  PHE B CA  1 
ATOM   5756 C C   . PHE B 1 404 ? 125.029 90.171  138.189 1.00 221.39 ?  404  PHE B C   1 
ATOM   5757 O O   . PHE B 1 404 ? 125.825 90.484  139.063 1.00 221.39 ?  404  PHE B O   1 
ATOM   5758 C CB  . PHE B 1 404 ? 126.198 89.414  136.142 1.00 221.39 ?  404  PHE B CB  1 
ATOM   5759 C CG  . PHE B 1 404 ? 127.208 88.390  135.738 1.00 221.39 ?  404  PHE B CG  1 
ATOM   5760 C CD1 . PHE B 1 404 ? 128.441 88.342  136.354 1.00 221.39 ?  404  PHE B CD1 1 
ATOM   5761 C CD2 . PHE B 1 404 ? 126.931 87.487  134.730 1.00 221.39 ?  404  PHE B CD2 1 
ATOM   5762 C CE1 . PHE B 1 404 ? 129.380 87.402  135.981 1.00 221.39 ?  404  PHE B CE1 1 
ATOM   5763 C CE2 . PHE B 1 404 ? 127.861 86.546  134.348 1.00 221.39 ?  404  PHE B CE2 1 
ATOM   5764 C CZ  . PHE B 1 404 ? 129.090 86.503  134.975 1.00 221.39 ?  404  PHE B CZ  1 
ATOM   5765 N N   . THR B 1 405 ? 123.901 90.842  137.984 1.00 183.45 ?  405  THR B N   1 
ATOM   5766 C CA  . THR B 1 405 ? 123.544 91.956  138.846 1.00 183.45 ?  405  THR B CA  1 
ATOM   5767 C C   . THR B 1 405 ? 122.659 91.505  139.977 1.00 183.45 ?  405  THR B C   1 
ATOM   5768 O O   . THR B 1 405 ? 122.124 92.342  140.686 1.00 183.45 ?  405  THR B O   1 
ATOM   5769 C CB  . THR B 1 405 ? 122.811 93.086  138.102 1.00 183.45 ?  405  THR B CB  1 
ATOM   5770 O OG1 . THR B 1 405 ? 121.623 92.576  137.490 1.00 183.45 ?  405  THR B OG1 1 
ATOM   5771 C CG2 . THR B 1 405 ? 123.694 93.717  137.060 1.00 183.45 ?  405  THR B CG2 1 
ATOM   5772 N N   . PHE B 1 406 ? 122.481 90.199  140.139 1.00 174.21 ?  406  PHE B N   1 
ATOM   5773 C CA  . PHE B 1 406 ? 121.702 89.670  141.249 1.00 174.21 ?  406  PHE B CA  1 
ATOM   5774 C C   . PHE B 1 406 ? 122.397 90.087  142.522 1.00 174.21 ?  406  PHE B C   1 
ATOM   5775 O O   . PHE B 1 406 ? 123.524 89.676  142.760 1.00 174.21 ?  406  PHE B O   1 
ATOM   5776 C CB  . PHE B 1 406 ? 121.614 88.150  141.148 1.00 174.21 ?  406  PHE B CB  1 
ATOM   5777 C CG  . PHE B 1 406 ? 120.756 87.515  142.201 1.00 174.21 ?  406  PHE B CG  1 
ATOM   5778 C CD1 . PHE B 1 406 ? 119.499 88.011  142.483 1.00 174.21 ?  406  PHE B CD1 1 
ATOM   5779 C CD2 . PHE B 1 406 ? 121.208 86.411  142.901 1.00 174.21 ?  406  PHE B CD2 1 
ATOM   5780 C CE1 . PHE B 1 406 ? 118.716 87.434  143.458 1.00 174.21 ?  406  PHE B CE1 1 
ATOM   5781 C CE2 . PHE B 1 406 ? 120.423 85.818  143.867 1.00 174.21 ?  406  PHE B CE2 1 
ATOM   5782 C CZ  . PHE B 1 406 ? 119.174 86.330  144.147 1.00 174.21 ?  406  PHE B CZ  1 
ATOM   5783 N N   . PRO B 1 407 ? 121.727 90.898  143.356 1.00 178.86 ?  407  PRO B N   1 
ATOM   5784 C CA  . PRO B 1 407 ? 122.403 91.430  144.546 1.00 178.86 ?  407  PRO B CA  1 
ATOM   5785 C C   . PRO B 1 407 ? 123.115 90.453  145.498 1.00 178.86 ?  407  PRO B C   1 
ATOM   5786 O O   . PRO B 1 407 ? 124.184 90.809  145.960 1.00 178.86 ?  407  PRO B O   1 
ATOM   5787 C CB  . PRO B 1 407 ? 121.313 92.271  145.227 1.00 178.86 ?  407  PRO B CB  1 
ATOM   5788 C CG  . PRO B 1 407 ? 120.363 92.604  144.131 1.00 178.86 ?  407  PRO B CG  1 
ATOM   5789 C CD  . PRO B 1 407 ? 120.348 91.398  143.248 1.00 178.86 ?  407  PRO B CD  1 
ATOM   5790 N N   . PRO B 1 408 ? 122.553 89.263  145.804 1.00 194.77 ?  408  PRO B N   1 
ATOM   5791 C CA  . PRO B 1 408 ? 123.341 88.362  146.655 1.00 194.77 ?  408  PRO B CA  1 
ATOM   5792 C C   . PRO B 1 408 ? 124.347 87.505  145.895 1.00 194.77 ?  408  PRO B C   1 
ATOM   5793 O O   . PRO B 1 408 ? 125.119 86.797  146.530 1.00 194.77 ?  408  PRO B O   1 
ATOM   5794 C CB  . PRO B 1 408 ? 122.276 87.455  147.277 1.00 194.77 ?  408  PRO B CB  1 
ATOM   5795 C CG  . PRO B 1 408 ? 121.010 88.217  147.164 1.00 194.77 ?  408  PRO B CG  1 
ATOM   5796 C CD  . PRO B 1 408 ? 121.142 88.858  145.827 1.00 194.77 ?  408  PRO B CD  1 
ATOM   5797 N N   . GLY B 1 409 ? 124.336 87.557  144.570 1.00 199.57 ?  409  GLY B N   1 
ATOM   5798 C CA  . GLY B 1 409 ? 125.248 86.759  143.779 1.00 199.57 ?  409  GLY B CA  1 
ATOM   5799 C C   . GLY B 1 409 ? 126.534 87.488  143.475 1.00 199.57 ?  409  GLY B C   1 
ATOM   5800 O O   . GLY B 1 409 ? 127.478 87.444  144.254 1.00 199.57 ?  409  GLY B O   1 
ATOM   5801 N N   . MET B 1 410 ? 126.586 88.158  142.334 1.00 185.66 ?  410  MET B N   1 
ATOM   5802 C CA  . MET B 1 410 ? 127.769 88.925  141.983 1.00 185.66 ?  410  MET B CA  1 
ATOM   5803 C C   . MET B 1 410 ? 127.475 90.399  142.152 1.00 185.66 ?  410  MET B C   1 
ATOM   5804 O O   . MET B 1 410 ? 128.389 91.209  142.214 1.00 185.66 ?  410  MET B O   1 
ATOM   5805 C CB  . MET B 1 410 ? 128.202 88.620  140.551 1.00 185.66 ?  410  MET B CB  1 
ATOM   5806 C CG  . MET B 1 410 ? 129.702 88.681  140.325 1.00 185.66 ?  410  MET B CG  1 
ATOM   5807 S SD  . MET B 1 410 ? 130.178 90.086  139.302 1.00 185.66 ?  410  MET B SD  1 
ATOM   5808 C CE  . MET B 1 410 ? 131.460 90.832  140.302 1.00 185.66 ?  410  MET B CE  1 
ATOM   5809 N N   . GLY B 1 411 ? 126.202 90.751  142.281 1.00 195.24 ?  411  GLY B N   1 
ATOM   5810 C CA  . GLY B 1 411 ? 125.814 92.140  142.437 1.00 195.24 ?  411  GLY B CA  1 
ATOM   5811 C C   . GLY B 1 411 ? 126.110 92.759  143.782 1.00 195.24 ?  411  GLY B C   1 
ATOM   5812 O O   . GLY B 1 411 ? 125.654 93.861  144.064 1.00 195.24 ?  411  GLY B O   1 
ATOM   5813 N N   . GLN B 1 412 ? 126.853 92.062  144.630 1.00 219.13 ?  412  GLN B N   1 
ATOM   5814 C CA  . GLN B 1 412 ? 127.247 92.623  145.903 1.00 219.13 ?  412  GLN B CA  1 
ATOM   5815 C C   . GLN B 1 412 ? 128.622 93.206  145.718 1.00 219.13 ?  412  GLN B C   1 
ATOM   5816 O O   . GLN B 1 412 ? 129.072 94.024  146.513 1.00 219.13 ?  412  GLN B O   1 
ATOM   5817 C CB  . GLN B 1 412 ? 127.292 91.534  146.957 1.00 219.13 ?  412  GLN B CB  1 
ATOM   5818 C CG  . GLN B 1 412 ? 127.543 90.147  146.403 1.00 219.13 ?  412  GLN B CG  1 
ATOM   5819 C CD  . GLN B 1 412 ? 127.730 89.126  147.500 1.00 219.13 ?  412  GLN B CD  1 
ATOM   5820 O OE1 . GLN B 1 412 ? 127.781 89.471  148.678 1.00 219.13 ?  412  GLN B OE1 1 
ATOM   5821 N NE2 . GLN B 1 412 ? 127.833 87.861  147.122 1.00 219.13 ?  412  GLN B NE2 1 
ATOM   5822 N N   . PHE B 1 413 ? 129.297 92.792  144.654 1.00 216.77 ?  413  PHE B N   1 
ATOM   5823 C CA  . PHE B 1 413 ? 130.632 93.286  144.387 1.00 216.77 ?  413  PHE B CA  1 
ATOM   5824 C C   . PHE B 1 413 ? 130.609 94.297  143.263 1.00 216.77 ?  413  PHE B C   1 
ATOM   5825 O O   . PHE B 1 413 ? 131.655 94.743  142.821 1.00 216.77 ?  413  PHE B O   1 
ATOM   5826 C CB  . PHE B 1 413 ? 131.563 92.143  143.994 1.00 216.77 ?  413  PHE B CB  1 
ATOM   5827 C CG  . PHE B 1 413 ? 131.427 90.923  144.849 1.00 216.77 ?  413  PHE B CG  1 
ATOM   5828 C CD1 . PHE B 1 413 ? 131.700 90.974  146.204 1.00 216.77 ?  413  PHE B CD1 1 
ATOM   5829 C CD2 . PHE B 1 413 ? 131.041 89.717  144.293 1.00 216.77 ?  413  PHE B CD2 1 
ATOM   5830 C CE1 . PHE B 1 413 ? 131.579 89.849  146.989 1.00 216.77 ?  413  PHE B CE1 1 
ATOM   5831 C CE2 . PHE B 1 413 ? 130.920 88.586  145.074 1.00 216.77 ?  413  PHE B CE2 1 
ATOM   5832 C CZ  . PHE B 1 413 ? 131.194 88.653  146.424 1.00 216.77 ?  413  PHE B CZ  1 
ATOM   5833 N N   . MET B 1 414 ? 129.424 94.649  142.790 1.00 192.46 ?  414  MET B N   1 
ATOM   5834 C CA  . MET B 1 414 ? 129.311 95.595  141.696 1.00 192.46 ?  414  MET B CA  1 
ATOM   5835 C C   . MET B 1 414 ? 128.071 96.453  141.843 1.00 192.46 ?  414  MET B C   1 
ATOM   5836 O O   . MET B 1 414 ? 127.643 97.057  140.876 1.00 192.46 ?  414  MET B O   1 
ATOM   5837 C CB  . MET B 1 414 ? 129.279 94.867  140.350 1.00 192.46 ?  414  MET B CB  1 
ATOM   5838 C CG  . MET B 1 414 ? 128.188 93.819  140.233 1.00 192.46 ?  414  MET B CG  1 
ATOM   5839 S SD  . MET B 1 414 ? 127.480 93.604  138.592 1.00 192.46 ?  414  MET B SD  1 
ATOM   5840 C CE  . MET B 1 414 ? 127.219 95.297  138.074 1.00 192.46 ?  414  MET B CE  1 
ATOM   5841 N N   . ALA B 1 415 ? 127.494 96.510  143.039 1.00 185.24 ?  415  ALA B N   1 
ATOM   5842 C CA  . ALA B 1 415 ? 126.263 97.274  143.272 1.00 185.24 ?  415  ALA B CA  1 
ATOM   5843 C C   . ALA B 1 415 ? 125.212 97.023  142.208 1.00 185.24 ?  415  ALA B C   1 
ATOM   5844 O O   . ALA B 1 415 ? 124.760 97.953  141.548 1.00 185.24 ?  415  ALA B O   1 
ATOM   5845 C CB  . ALA B 1 415 ? 126.546 98.763  143.415 1.00 185.24 ?  415  ALA B CB  1 
ATOM   5846 N N   . GLY B 1 416 ? 124.807 95.769  142.049 1.00 188.90 ?  416  GLY B N   1 
ATOM   5847 C CA  . GLY B 1 416 ? 123.809 95.422  141.056 1.00 188.90 ?  416  GLY B CA  1 
ATOM   5848 C C   . GLY B 1 416 ? 122.421 95.784  141.512 1.00 188.90 ?  416  GLY B C   1 
ATOM   5849 O O   . GLY B 1 416 ? 121.521 95.902  140.691 1.00 188.90 ?  416  GLY B O   1 
ATOM   5850 N N   . GLU B 1 417 ? 122.253 95.986  142.814 1.00 190.96 ?  417  GLU B N   1 
ATOM   5851 C CA  . GLU B 1 417 ? 120.967 96.398  143.366 1.00 190.96 ?  417  GLU B CA  1 
ATOM   5852 C C   . GLU B 1 417 ? 120.602 97.740  142.784 1.00 190.96 ?  417  GLU B C   1 
ATOM   5853 O O   . GLU B 1 417 ? 119.435 98.012  142.503 1.00 190.96 ?  417  GLU B O   1 
ATOM   5854 C CB  . GLU B 1 417 ? 121.090 96.504  144.891 1.00 190.96 ?  417  GLU B CB  1 
ATOM   5855 C CG  . GLU B 1 417 ? 119.942 97.216  145.596 1.00 190.96 ?  417  GLU B CG  1 
ATOM   5856 C CD  . GLU B 1 417 ? 120.417 98.114  146.722 1.00 190.96 ?  417  GLU B CD  1 
ATOM   5857 O OE1 . GLU B 1 417 ? 119.571 98.616  147.489 1.00 190.96 ?  417  GLU B OE1 1 
ATOM   5858 O OE2 . GLU B 1 417 ? 121.643 98.320  146.846 1.00 190.96 ?  417  GLU B OE2 1 
ATOM   5859 N N   . LEU B 1 418 ? 121.604 98.579  142.570 1.00 187.00 ?  418  LEU B N   1 
ATOM   5860 C CA  . LEU B 1 418 ? 121.368 99.906  142.042 1.00 187.00 ?  418  LEU B CA  1 
ATOM   5861 C C   . LEU B 1 418 ? 120.961 99.887  140.591 1.00 187.00 ?  418  LEU B C   1 
ATOM   5862 O O   . LEU B 1 418 ? 121.595 99.236  139.770 1.00 187.00 ?  418  LEU B O   1 
ATOM   5863 C CB  . LEU B 1 418 ? 122.605 100.771 142.221 1.00 187.00 ?  418  LEU B CB  1 
ATOM   5864 C CG  . LEU B 1 418 ? 122.784 101.313 143.631 1.00 187.00 ?  418  LEU B CG  1 
ATOM   5865 C CD1 . LEU B 1 418 ? 123.574 102.598 143.589 1.00 187.00 ?  418  LEU B CD1 1 
ATOM   5866 C CD2 . LEU B 1 418 ? 121.467 101.519 144.358 1.00 187.00 ?  418  LEU B CD2 1 
ATOM   5867 N N   . MET B 1 419 ? 119.899 100.610 140.273 1.00 204.53 ?  419  MET B N   1 
ATOM   5868 C CA  . MET B 1 419 ? 119.440 100.695 138.903 1.00 204.53 ?  419  MET B CA  1 
ATOM   5869 C C   . MET B 1 419 ? 120.119 101.911 138.302 1.00 204.53 ?  419  MET B C   1 
ATOM   5870 O O   . MET B 1 419 ? 120.620 102.736 139.046 1.00 204.53 ?  419  MET B O   1 
ATOM   5871 C CB  . MET B 1 419 ? 117.915 100.805 138.893 1.00 204.53 ?  419  MET B CB  1 
ATOM   5872 C CG  . MET B 1 419 ? 117.225 99.503  138.510 1.00 204.53 ?  419  MET B CG  1 
ATOM   5873 S SD  . MET B 1 419 ? 117.696 98.072  139.502 1.00 204.53 ?  419  MET B SD  1 
ATOM   5874 C CE  . MET B 1 419 ? 118.515 97.032  138.296 1.00 204.53 ?  419  MET B CE  1 
ATOM   5875 N N   . PRO B 1 420 ? 120.187 102.013 136.962 1.00 156.73 ?  420  PRO B N   1 
ATOM   5876 C CA  . PRO B 1 420 ? 120.908 103.126 136.332 1.00 156.73 ?  420  PRO B CA  1 
ATOM   5877 C C   . PRO B 1 420 ? 120.813 104.501 137.008 1.00 156.73 ?  420  PRO B C   1 
ATOM   5878 O O   . PRO B 1 420 ? 121.846 105.089 137.279 1.00 156.73 ?  420  PRO B O   1 
ATOM   5879 C CB  . PRO B 1 420 ? 120.295 103.163 134.938 1.00 156.73 ?  420  PRO B CB  1 
ATOM   5880 C CG  . PRO B 1 420 ? 119.959 101.734 134.648 1.00 156.73 ?  420  PRO B CG  1 
ATOM   5881 C CD  . PRO B 1 420 ? 119.820 100.999 135.957 1.00 156.73 ?  420  PRO B CD  1 
ATOM   5882 N N   . ARG B 1 421 ? 119.616 104.994 137.295 1.00 168.32 ?  421  ARG B N   1 
ATOM   5883 C CA  . ARG B 1 421 ? 119.466 106.329 137.873 1.00 168.32 ?  421  ARG B CA  1 
ATOM   5884 C C   . ARG B 1 421 ? 119.959 106.395 139.303 1.00 168.32 ?  421  ARG B C   1 
ATOM   5885 O O   . ARG B 1 421 ? 120.545 107.392 139.707 1.00 168.32 ?  421  ARG B O   1 
ATOM   5886 C CB  . ARG B 1 421 ? 118.014 106.784 137.794 1.00 168.32 ?  421  ARG B CB  1 
ATOM   5887 C CG  . ARG B 1 421 ? 117.061 105.702 137.318 1.00 168.32 ?  421  ARG B CG  1 
ATOM   5888 C CD  . ARG B 1 421 ? 116.144 105.239 138.437 1.00 168.32 ?  421  ARG B CD  1 
ATOM   5889 N NE  . ARG B 1 421 ? 116.062 106.216 139.519 1.00 168.32 ?  421  ARG B NE  1 
ATOM   5890 C CZ  . ARG B 1 421 ? 116.060 105.897 140.809 1.00 168.32 ?  421  ARG B CZ  1 
ATOM   5891 N NH1 . ARG B 1 421 ? 116.139 104.627 141.177 1.00 168.32 ?  421  ARG B NH1 1 
ATOM   5892 N NH2 . ARG B 1 421 ? 115.983 106.848 141.729 1.00 168.32 ?  421  ARG B NH2 1 
ATOM   5893 N N   . GLU B 1 422 ? 119.724 105.360 140.103 1.00 196.80 ?  422  GLU B N   1 
ATOM   5894 C CA  . GLU B 1 422 ? 120.264 105.372 141.462 1.00 196.80 ?  422  GLU B CA  1 
ATOM   5895 C C   . GLU B 1 422 ? 121.773 105.335 141.435 1.00 196.80 ?  422  GLU B C   1 
ATOM   5896 O O   . GLU B 1 422 ? 122.418 105.977 142.253 1.00 196.80 ?  422  GLU B O   1 
ATOM   5897 C CB  . GLU B 1 422 ? 119.734 104.240 142.337 1.00 196.80 ?  422  GLU B CB  1 
ATOM   5898 C CG  . GLU B 1 422 ? 118.830 103.246 141.659 1.00 196.80 ?  422  GLU B CG  1 
ATOM   5899 C CD  . GLU B 1 422 ? 118.043 102.414 142.649 1.00 196.80 ?  422  GLU B CD  1 
ATOM   5900 O OE1 . GLU B 1 422 ? 117.172 102.979 143.340 1.00 196.80 ?  422  GLU B OE1 1 
ATOM   5901 O OE2 . GLU B 1 422 ? 118.294 101.196 142.738 1.00 196.80 ?  422  GLU B OE2 1 
ATOM   5902 N N   . ALA B 1 423 ? 122.341 104.595 140.492 1.00 179.55 ?  423  ALA B N   1 
ATOM   5903 C CA  . ALA B 1 423 ? 123.786 104.536 140.368 1.00 179.55 ?  423  ALA B CA  1 
ATOM   5904 C C   . ALA B 1 423 ? 124.378 105.928 140.291 1.00 179.55 ?  423  ALA B C   1 
ATOM   5905 O O   . ALA B 1 423 ? 125.241 106.267 141.075 1.00 179.55 ?  423  ALA B O   1 
ATOM   5906 C CB  . ALA B 1 423 ? 124.193 103.713 139.162 1.00 179.55 ?  423  ALA B CB  1 
ATOM   5907 N N   . ILE B 1 424 ? 123.901 106.746 139.365 1.00 178.19 ?  424  ILE B N   1 
ATOM   5908 C CA  . ILE B 1 424 ? 124.397 108.110 139.243 1.00 178.19 ?  424  ILE B CA  1 
ATOM   5909 C C   . ILE B 1 424 ? 124.135 108.931 140.487 1.00 178.19 ?  424  ILE B C   1 
ATOM   5910 O O   . ILE B 1 424 ? 125.025 109.603 140.982 1.00 178.19 ?  424  ILE B O   1 
ATOM   5911 C CB  . ILE B 1 424 ? 123.788 108.830 138.041 1.00 178.19 ?  424  ILE B CB  1 
ATOM   5912 C CG1 . ILE B 1 424 ? 124.276 108.187 136.767 1.00 178.19 ?  424  ILE B CG1 1 
ATOM   5913 C CG2 . ILE B 1 424 ? 124.173 110.292 138.016 1.00 178.19 ?  424  ILE B CG2 1 
ATOM   5914 C CD1 . ILE B 1 424 ? 123.120 107.697 135.964 1.00 178.19 ?  424  ILE B CD1 1 
ATOM   5915 N N   . SER B 1 425 ? 122.921 108.864 141.011 1.00 211.65 ?  425  SER B N   1 
ATOM   5916 C CA  . SER B 1 425 ? 122.594 109.602 142.217 1.00 211.65 ?  425  SER B CA  1 
ATOM   5917 C C   . SER B 1 425 ? 123.622 109.337 143.304 1.00 211.65 ?  425  SER B C   1 
ATOM   5918 O O   . SER B 1 425 ? 124.007 110.249 144.034 1.00 211.65 ?  425  SER B O   1 
ATOM   5919 C CB  . SER B 1 425 ? 121.190 109.250 142.703 1.00 211.65 ?  425  SER B CB  1 
ATOM   5920 O OG  . SER B 1 425 ? 121.229 108.344 143.790 1.00 211.65 ?  425  SER B OG  1 
ATOM   5921 N N   . THR B 1 426 ? 124.077 108.094 143.409 1.00 195.45 ?  426  THR B N   1 
ATOM   5922 C CA  . THR B 1 426 ? 125.067 107.758 144.416 1.00 195.45 ?  426  THR B CA  1 
ATOM   5923 C C   . THR B 1 426 ? 126.484 108.128 143.984 1.00 195.45 ?  426  THR B C   1 
ATOM   5924 O O   . THR B 1 426 ? 127.263 108.652 144.783 1.00 195.45 ?  426  THR B O   1 
ATOM   5925 C CB  . THR B 1 426 ? 124.998 106.275 144.788 1.00 195.45 ?  426  THR B CB  1 
ATOM   5926 O OG1 . THR B 1 426 ? 125.248 105.481 143.626 1.00 195.45 ?  426  THR B OG1 1 
ATOM   5927 C CG2 . THR B 1 426 ? 123.632 105.939 145.335 1.00 195.45 ?  426  THR B CG2 1 
ATOM   5928 N N   . LEU B 1 427 ? 126.818 107.871 142.723 1.00 191.14 ?  427  LEU B N   1 
ATOM   5929 C CA  . LEU B 1 427 ? 128.154 108.186 142.243 1.00 191.14 ?  427  LEU B CA  1 
ATOM   5930 C C   . LEU B 1 427 ? 128.384 109.688 142.232 1.00 191.14 ?  427  LEU B C   1 
ATOM   5931 O O   . LEU B 1 427 ? 129.518 110.135 142.247 1.00 191.14 ?  427  LEU B O   1 
ATOM   5932 C CB  . LEU B 1 427 ? 128.398 107.589 140.854 1.00 191.14 ?  427  LEU B CB  1 
ATOM   5933 C CG  . LEU B 1 427 ? 128.536 106.069 140.743 1.00 191.14 ?  427  LEU B CG  1 
ATOM   5934 C CD1 . LEU B 1 427 ? 128.114 105.553 139.378 1.00 191.14 ?  427  LEU B CD1 1 
ATOM   5935 C CD2 . LEU B 1 427 ? 129.945 105.618 141.058 1.00 191.14 ?  427  LEU B CD2 1 
ATOM   5936 N N   . PHE B 1 428 ? 127.313 110.474 142.227 1.00 213.07 ?  428  PHE B N   1 
ATOM   5937 C CA  . PHE B 1 428 ? 127.433 111.923 142.219 1.00 213.07 ?  428  PHE B CA  1 
ATOM   5938 C C   . PHE B 1 428 ? 127.245 112.464 143.631 1.00 213.07 ?  428  PHE B C   1 
ATOM   5939 O O   . PHE B 1 428 ? 126.781 113.583 143.804 1.00 213.07 ?  428  PHE B O   1 
ATOM   5940 C CB  . PHE B 1 428 ? 126.369 112.541 141.316 1.00 213.07 ?  428  PHE B CB  1 
ATOM   5941 C CG  . PHE B 1 428 ? 126.676 112.479 139.840 1.00 213.07 ?  428  PHE B CG  1 
ATOM   5942 C CD1 . PHE B 1 428 ? 127.693 111.689 139.336 1.00 213.07 ?  428  PHE B CD1 1 
ATOM   5943 C CD2 . PHE B 1 428 ? 125.915 113.217 138.951 1.00 213.07 ?  428  PHE B CD2 1 
ATOM   5944 C CE1 . PHE B 1 428 ? 127.944 111.639 137.983 1.00 213.07 ?  428  PHE B CE1 1 
ATOM   5945 C CE2 . PHE B 1 428 ? 126.168 113.179 137.595 1.00 213.07 ?  428  PHE B CE2 1 
ATOM   5946 C CZ  . PHE B 1 428 ? 127.185 112.387 137.110 1.00 213.07 ?  428  PHE B CZ  1 
ATOM   5947 N N   . ASP B 1 429 ? 127.579 111.673 144.640 1.00 254.83 ?  429  ASP B N   1 
ATOM   5948 C CA  . ASP B 1 429 ? 127.375 112.146 145.996 1.00 254.83 ?  429  ASP B CA  1 
ATOM   5949 C C   . ASP B 1 429 ? 128.527 112.977 146.546 1.00 254.83 ?  429  ASP B C   1 
ATOM   5950 O O   . ASP B 1 429 ? 129.631 112.937 146.009 1.00 254.83 ?  429  ASP B O   1 
ATOM   5951 C CB  . ASP B 1 429 ? 126.746 111.088 146.938 1.00 254.83 ?  429  ASP B CB  1 
ATOM   5952 C CG  . ASP B 1 429 ? 127.746 110.212 147.656 1.00 254.83 ?  429  ASP B CG  1 
ATOM   5953 O OD1 . ASP B 1 429 ? 128.894 110.077 147.234 1.00 254.83 ?  429  ASP B OD1 1 
ATOM   5954 O OD2 . ASP B 1 429 ? 127.350 109.607 148.667 1.00 254.83 ?  429  ASP B OD2 1 
ATOM   5955 N N   . ASN B 1 430 ? 128.281 113.728 147.601 1.00 236.43 ?  430  ASN B N   1 
ATOM   5956 C CA  . ASN B 1 430 ? 129.268 114.644 148.144 1.00 236.43 ?  430  ASN B CA  1 
ATOM   5957 C C   . ASN B 1 430 ? 130.032 113.977 149.263 1.00 236.43 ?  430  ASN B C   1 
ATOM   5958 O O   . ASN B 1 430 ? 130.622 114.649 150.102 1.00 236.43 ?  430  ASN B O   1 
ATOM   5959 C CB  . ASN B 1 430 ? 128.588 115.905 148.665 1.00 236.43 ?  430  ASN B CB  1 
ATOM   5960 C CG  . ASN B 1 430 ? 127.157 115.662 149.088 1.00 236.43 ?  430  ASN B CG  1 
ATOM   5961 O OD1 . ASN B 1 430 ? 126.233 115.799 148.290 1.00 236.43 ?  430  ASN B OD1 1 
ATOM   5962 N ND2 . ASN B 1 430 ? 126.965 115.305 150.353 1.00 236.43 ?  430  ASN B ND2 1 
ATOM   5963 N N   . ASN B 1 431 ? 130.027 112.652 149.285 1.00 238.46 ?  431  ASN B N   1 
ATOM   5964 C CA  . ASN B 1 431 ? 130.711 111.918 150.330 1.00 238.46 ?  431  ASN B CA  1 
ATOM   5965 C C   . ASN B 1 431 ? 131.992 111.334 149.804 1.00 238.46 ?  431  ASN B C   1 
ATOM   5966 O O   . ASN B 1 431 ? 132.268 111.424 148.616 1.00 238.46 ?  431  ASN B O   1 
ATOM   5967 C CB  . ASN B 1 431 ? 129.824 110.786 150.836 1.00 238.46 ?  431  ASN B CB  1 
ATOM   5968 C CG  . ASN B 1 431 ? 128.615 111.286 151.590 1.00 238.46 ?  431  ASN B CG  1 
ATOM   5969 O OD1 . ASN B 1 431 ? 127.495 110.841 151.353 1.00 238.46 ?  431  ASN B OD1 1 
ATOM   5970 N ND2 . ASN B 1 431 ? 128.836 112.217 152.509 1.00 238.46 ?  431  ASN B ND2 1 
ATOM   5971 N N   . THR B 1 432 ? 132.800 110.766 150.683 1.00 235.80 ?  432  THR B N   1 
ATOM   5972 C CA  . THR B 1 432 ? 134.002 110.087 150.243 1.00 235.80 ?  432  THR B CA  1 
ATOM   5973 C C   . THR B 1 432 ? 133.799 108.688 150.747 1.00 235.80 ?  432  THR B C   1 
ATOM   5974 O O   . THR B 1 432 ? 133.893 108.438 151.940 1.00 235.80 ?  432  THR B O   1 
ATOM   5975 C CB  . THR B 1 432 ? 135.269 110.693 150.844 1.00 235.80 ?  432  THR B CB  1 
ATOM   5976 O OG1 . THR B 1 432 ? 135.350 112.078 150.492 1.00 235.80 ?  432  THR B OG1 1 
ATOM   5977 C CG2 . THR B 1 432 ? 136.490 109.981 150.317 1.00 235.80 ?  432  THR B CG2 1 
ATOM   5978 N N   . TRP B 1 433 ? 133.499 107.762 149.854 1.00 195.77 ?  433  TRP B N   1 
ATOM   5979 C CA  . TRP B 1 433 ? 133.180 106.410 150.281 1.00 195.77 ?  433  TRP B CA  1 
ATOM   5980 C C   . TRP B 1 433 ? 134.333 105.714 150.947 1.00 195.77 ?  433  TRP B C   1 
ATOM   5981 O O   . TRP B 1 433 ? 134.137 104.899 151.841 1.00 195.77 ?  433  TRP B O   1 
ATOM   5982 C CB  . TRP B 1 433 ? 132.745 105.593 149.084 1.00 195.77 ?  433  TRP B CB  1 
ATOM   5983 C CG  . TRP B 1 433 ? 131.517 106.075 148.429 1.00 195.77 ?  433  TRP B CG  1 
ATOM   5984 C CD1 . TRP B 1 433 ? 130.548 106.862 148.969 1.00 195.77 ?  433  TRP B CD1 1 
ATOM   5985 C CD2 . TRP B 1 433 ? 131.108 105.794 147.094 1.00 195.77 ?  433  TRP B CD2 1 
ATOM   5986 N NE1 . TRP B 1 433 ? 129.565 107.097 148.050 1.00 195.77 ?  433  TRP B NE1 1 
ATOM   5987 C CE2 . TRP B 1 433 ? 129.883 106.443 146.890 1.00 195.77 ?  433  TRP B CE2 1 
ATOM   5988 C CE3 . TRP B 1 433 ? 131.661 105.055 146.049 1.00 195.77 ?  433  TRP B CE3 1 
ATOM   5989 C CZ2 . TRP B 1 433 ? 129.205 106.377 145.689 1.00 195.77 ?  433  TRP B CZ2 1 
ATOM   5990 C CZ3 . TRP B 1 433 ? 130.984 104.992 144.862 1.00 195.77 ?  433  TRP B CZ3 1 
ATOM   5991 C CH2 . TRP B 1 433 ? 129.773 105.655 144.687 1.00 195.77 ?  433  TRP B CH2 1 
ATOM   5992 N N   . VAL B 1 434 ? 135.544 106.034 150.519 1.00 221.24 ?  434  VAL B N   1 
ATOM   5993 C CA  . VAL B 1 434 ? 136.725 105.395 151.072 1.00 221.24 ?  434  VAL B CA  1 
ATOM   5994 C C   . VAL B 1 434 ? 137.039 105.916 152.476 1.00 221.24 ?  434  VAL B C   1 
ATOM   5995 O O   . VAL B 1 434 ? 137.765 105.276 153.234 1.00 221.24 ?  434  VAL B O   1 
ATOM   5996 C CB  . VAL B 1 434 ? 137.907 105.498 150.081 1.00 221.24 ?  434  VAL B CB  1 
ATOM   5997 C CG1 . VAL B 1 434 ? 138.781 106.714 150.344 1.00 221.24 ?  434  VAL B CG1 1 
ATOM   5998 C CG2 . VAL B 1 434 ? 138.693 104.200 150.043 1.00 221.24 ?  434  VAL B CG2 1 
ATOM   5999 N N   . LYS B 1 435 ? 136.457 107.051 152.846 1.00 239.32 ?  435  LYS B N   1 
ATOM   6000 C CA  . LYS B 1 435 ? 136.655 107.588 154.185 1.00 239.32 ?  435  LYS B CA  1 
ATOM   6001 C C   . LYS B 1 435 ? 135.603 107.008 155.113 1.00 239.32 ?  435  LYS B C   1 
ATOM   6002 O O   . LYS B 1 435 ? 135.925 106.527 156.195 1.00 239.32 ?  435  LYS B O   1 
ATOM   6003 C CB  . LYS B 1 435 ? 136.546 109.111 154.172 1.00 239.32 ?  435  LYS B CB  1 
ATOM   6004 C CG  . LYS B 1 435 ? 137.859 109.861 154.336 1.00 239.32 ?  435  LYS B CG  1 
ATOM   6005 C CD  . LYS B 1 435 ? 139.065 108.999 154.003 1.00 239.32 ?  435  LYS B CD  1 
ATOM   6006 C CE  . LYS B 1 435 ? 139.940 109.652 152.947 1.00 239.32 ?  435  LYS B CE  1 
ATOM   6007 N NZ  . LYS B 1 435 ? 141.026 108.735 152.503 1.00 239.32 ?  435  LYS B NZ  1 
ATOM   6008 N N   . HIS B 1 436 ? 134.344 107.041 154.692 1.00 281.37 ?  436  HIS B N   1 
ATOM   6009 C CA  . HIS B 1 436 ? 133.259 106.519 155.520 1.00 281.37 ?  436  HIS B CA  1 
ATOM   6010 C C   . HIS B 1 436 ? 132.956 105.081 155.156 1.00 281.37 ?  436  HIS B C   1 
ATOM   6011 O O   . HIS B 1 436 ? 131.829 104.750 154.800 1.00 281.37 ?  436  HIS B O   1 
ATOM   6012 C CB  . HIS B 1 436 ? 131.983 107.362 155.391 1.00 281.37 ?  436  HIS B CB  1 
ATOM   6013 C CG  . HIS B 1 436 ? 132.216 108.771 154.942 1.00 281.37 ?  436  HIS B CG  1 
ATOM   6014 N ND1 . HIS B 1 436 ? 133.065 109.637 155.597 1.00 281.37 ?  436  HIS B ND1 1 
ATOM   6015 C CD2 . HIS B 1 436 ? 131.683 109.476 153.916 1.00 281.37 ?  436  HIS B CD2 1 
ATOM   6016 C CE1 . HIS B 1 436 ? 133.065 110.805 154.978 1.00 281.37 ?  436  HIS B CE1 1 
ATOM   6017 N NE2 . HIS B 1 436 ? 132.234 110.733 153.955 1.00 281.37 ?  436  HIS B NE2 1 
ATOM   6018 N N   . ALA B 1 437 ? 133.964 104.226 155.234 1.00 293.73 ?  437  ALA B N   1 
ATOM   6019 C CA  . ALA B 1 437 ? 133.776 102.825 154.908 1.00 293.73 ?  437  ALA B CA  1 
ATOM   6020 C C   . ALA B 1 437 ? 133.548 102.059 156.189 1.00 293.73 ?  437  ALA B C   1 
ATOM   6021 O O   . ALA B 1 437 ? 132.770 101.108 156.219 1.00 293.73 ?  437  ALA B O   1 
ATOM   6022 C CB  . ALA B 1 437 ? 134.992 102.289 154.175 1.00 293.73 ?  437  ALA B CB  1 
ATOM   6023 N N   . GLY B 1 438 ? 134.225 102.475 157.257 1.00 306.05 ?  438  GLY B N   1 
ATOM   6024 C CA  . GLY B 1 438 ? 134.039 101.835 158.546 1.00 306.05 ?  438  GLY B CA  1 
ATOM   6025 C C   . GLY B 1 438 ? 132.618 102.043 158.996 1.00 306.05 ?  438  GLY B C   1 
ATOM   6026 O O   . GLY B 1 438 ? 131.993 101.128 159.526 1.00 306.05 ?  438  GLY B O   1 
ATOM   6027 N N   . ASP B 1 439 ? 132.097 103.246 158.794 1.00 298.16 ?  439  ASP B N   1 
ATOM   6028 C CA  . ASP B 1 439 ? 130.706 103.505 159.118 1.00 298.16 ?  439  ASP B CA  1 
ATOM   6029 C C   . ASP B 1 439 ? 129.930 103.744 157.842 1.00 298.16 ?  439  ASP B C   1 
ATOM   6030 O O   . ASP B 1 439 ? 130.024 104.813 157.244 1.00 298.16 ?  439  ASP B O   1 
ATOM   6031 C CB  . ASP B 1 439 ? 130.577 104.724 160.028 1.00 298.16 ?  439  ASP B CB  1 
ATOM   6032 C CG  . ASP B 1 439 ? 129.132 105.077 160.326 1.00 298.16 ?  439  ASP B CG  1 
ATOM   6033 O OD1 . ASP B 1 439 ? 128.389 104.197 160.807 1.00 298.16 ?  439  ASP B OD1 1 
ATOM   6034 O OD2 . ASP B 1 439 ? 128.740 106.234 160.068 1.00 298.16 ?  439  ASP B OD2 1 
ATOM   6035 N N   . PRO B 1 440 ? 129.152 102.748 157.407 1.00 287.15 ?  440  PRO B N   1 
ATOM   6036 C CA  . PRO B 1 440 ? 128.312 103.003 156.242 1.00 287.15 ?  440  PRO B CA  1 
ATOM   6037 C C   . PRO B 1 440 ? 126.983 103.579 156.706 1.00 287.15 ?  440  PRO B C   1 
ATOM   6038 O O   . PRO B 1 440 ? 126.901 104.074 157.834 1.00 287.15 ?  440  PRO B O   1 
ATOM   6039 C CB  . PRO B 1 440 ? 128.114 101.611 155.631 1.00 287.15 ?  440  PRO B CB  1 
ATOM   6040 C CG  . PRO B 1 440 ? 128.803 100.641 156.544 1.00 287.15 ?  440  PRO B CG  1 
ATOM   6041 C CD  . PRO B 1 440 ? 129.061 101.347 157.836 1.00 287.15 ?  440  PRO B CD  1 
ATOM   6042 N N   . GLU B 1 441 ? 125.960 103.538 155.860 1.00 298.65 ?  441  GLU B N   1 
ATOM   6043 C CA  . GLU B 1 441 ? 124.643 104.094 156.200 1.00 298.65 ?  441  GLU B CA  1 
ATOM   6044 C C   . GLU B 1 441 ? 124.694 105.545 156.660 1.00 298.65 ?  441  GLU B C   1 
ATOM   6045 O O   . GLU B 1 441 ? 123.805 106.003 157.372 1.00 298.65 ?  441  GLU B O   1 
ATOM   6046 C CB  . GLU B 1 441 ? 123.897 103.212 157.212 1.00 298.65 ?  441  GLU B CB  1 
ATOM   6047 C CG  . GLU B 1 441 ? 123.790 101.751 156.806 1.00 298.65 ?  441  GLU B CG  1 
ATOM   6048 C CD  . GLU B 1 441 ? 124.782 100.870 157.541 1.00 298.65 ?  441  GLU B CD  1 
ATOM   6049 O OE1 . GLU B 1 441 ? 125.229 101.264 158.640 1.00 298.65 ?  441  GLU B OE1 1 
ATOM   6050 O OE2 . GLU B 1 441 ? 125.123 99.789  157.016 1.00 298.65 ?  441  GLU B OE2 1 
ATOM   6051 N N   . SER B 1 442 ? 125.724 106.274 156.251 1.00 305.90 ?  442  SER B N   1 
ATOM   6052 C CA  . SER B 1 442 ? 125.840 107.682 156.582 1.00 305.90 ?  442  SER B CA  1 
ATOM   6053 C C   . SER B 1 442 ? 125.847 108.271 155.205 1.00 305.90 ?  442  SER B C   1 
ATOM   6054 O O   . SER B 1 442 ? 125.718 109.479 155.025 1.00 305.90 ?  442  SER B O   1 
ATOM   6055 C CB  . SER B 1 442 ? 127.172 107.951 157.269 1.00 305.90 ?  442  SER B CB  1 
ATOM   6056 O OG  . SER B 1 442 ? 128.161 107.039 156.829 1.00 305.90 ?  442  SER B OG  1 
ATOM   6057 N N   . LEU B 1 443 ? 125.998 107.401 154.217 1.00 251.68 ?  443  LEU B N   1 
ATOM   6058 C CA  . LEU B 1 443 ? 126.016 107.840 152.841 1.00 251.68 ?  443  LEU B CA  1 
ATOM   6059 C C   . LEU B 1 443 ? 124.643 107.575 152.266 1.00 251.68 ?  443  LEU B C   1 
ATOM   6060 O O   . LEU B 1 443 ? 124.344 107.989 151.149 1.00 251.68 ?  443  LEU B O   1 
ATOM   6061 C CB  . LEU B 1 443 ? 127.092 107.075 152.083 1.00 251.68 ?  443  LEU B CB  1 
ATOM   6062 C CG  . LEU B 1 443 ? 128.247 106.565 152.941 1.00 251.68 ?  443  LEU B CG  1 
ATOM   6063 C CD1 . LEU B 1 443 ? 128.182 105.060 153.101 1.00 251.68 ?  443  LEU B CD1 1 
ATOM   6064 C CD2 . LEU B 1 443 ? 129.576 106.976 152.346 1.00 251.68 ?  443  LEU B CD2 1 
ATOM   6065 N N   . GLY B 1 444 ? 123.801 106.886 153.026 1.00 215.61 ?  444  GLY B N   1 
ATOM   6066 C CA  . GLY B 1 444 ? 122.442 106.642 152.584 1.00 215.61 ?  444  GLY B CA  1 
ATOM   6067 C C   . GLY B 1 444 ? 122.335 105.537 151.568 1.00 215.61 ?  444  GLY B C   1 
ATOM   6068 O O   . GLY B 1 444 ? 122.582 104.377 151.882 1.00 215.61 ?  444  GLY B O   1 
ATOM   6069 N N   . GLN B 1 445 ? 121.976 105.891 150.340 1.00 206.13 ?  445  GLN B N   1 
ATOM   6070 C CA  . GLN B 1 445 ? 121.842 104.899 149.284 1.00 206.13 ?  445  GLN B CA  1 
ATOM   6071 C C   . GLN B 1 445 ? 123.196 104.539 148.714 1.00 206.13 ?  445  GLN B C   1 
ATOM   6072 O O   . GLN B 1 445 ? 123.314 103.598 147.936 1.00 206.13 ?  445  GLN B O   1 
ATOM   6073 C CB  . GLN B 1 445 ? 120.933 105.423 148.180 1.00 206.13 ?  445  GLN B CB  1 
ATOM   6074 C CG  . GLN B 1 445 ? 119.852 104.443 147.758 1.00 206.13 ?  445  GLN B CG  1 
ATOM   6075 C CD  . GLN B 1 445 ? 119.605 104.450 146.264 1.00 206.13 ?  445  GLN B CD  1 
ATOM   6076 O OE1 . GLN B 1 445 ? 120.176 105.254 145.529 1.00 206.13 ?  445  GLN B OE1 1 
ATOM   6077 N NE2 . GLN B 1 445 ? 118.745 103.550 145.806 1.00 206.13 ?  445  GLN B NE2 1 
ATOM   6078 N N   . SER B 1 446 ? 124.229 105.272 149.111 1.00 199.99 ?  446  SER B N   1 
ATOM   6079 C CA  . SER B 1 446 ? 125.570 104.999 148.631 1.00 199.99 ?  446  SER B CA  1 
ATOM   6080 C C   . SER B 1 446 ? 126.283 104.052 149.568 1.00 199.99 ?  446  SER B C   1 
ATOM   6081 O O   . SER B 1 446 ? 127.506 103.959 149.544 1.00 199.99 ?  446  SER B O   1 
ATOM   6082 C CB  . SER B 1 446 ? 126.339 106.304 148.493 1.00 199.99 ?  446  SER B CB  1 
ATOM   6083 O OG  . SER B 1 446 ? 125.449 107.393 148.376 1.00 199.99 ?  446  SER B OG  1 
ATOM   6084 N N   . ALA B 1 447 ? 125.525 103.340 150.390 1.00 185.10 ?  447  ALA B N   1 
ATOM   6085 C CA  . ALA B 1 447 ? 126.105 102.378 151.309 1.00 185.10 ?  447  ALA B CA  1 
ATOM   6086 C C   . ALA B 1 447 ? 126.174 101.031 150.639 1.00 185.10 ?  447  ALA B C   1 
ATOM   6087 O O   . ALA B 1 447 ? 126.767 100.099 151.173 1.00 185.10 ?  447  ALA B O   1 
ATOM   6088 C CB  . ALA B 1 447 ? 125.266 102.289 152.564 1.00 185.10 ?  447  ALA B CB  1 
ATOM   6089 N N   . VAL B 1 448 ? 125.576 100.919 149.459 1.00 148.45 ?  448  VAL B N   1 
ATOM   6090 C CA  . VAL B 1 448 ? 125.618 99.674  148.711 1.00 148.45 ?  448  VAL B CA  1 
ATOM   6091 C C   . VAL B 1 448 ? 126.959 99.554  148.024 1.00 148.45 ?  448  VAL B C   1 
ATOM   6092 O O   . VAL B 1 448 ? 127.317 98.489  147.526 1.00 148.45 ?  448  VAL B O   1 
ATOM   6093 C CB  . VAL B 1 448 ? 124.496 99.625  147.664 1.00 148.45 ?  448  VAL B CB  1 
ATOM   6094 C CG1 . VAL B 1 448 ? 123.144 99.808  148.332 1.00 148.45 ?  448  VAL B CG1 1 
ATOM   6095 C CG2 . VAL B 1 448 ? 124.709 100.700 146.624 1.00 148.45 ?  448  VAL B CG2 1 
ATOM   6096 N N   . TRP B 1 449 ? 127.715 100.642 148.007 1.00 178.59 ?  449  TRP B N   1 
ATOM   6097 C CA  . TRP B 1 449 ? 129.021 100.627 147.399 1.00 178.59 ?  449  TRP B CA  1 
ATOM   6098 C C   . TRP B 1 449 ? 130.020 100.123 148.405 1.00 178.59 ?  449  TRP B C   1 
ATOM   6099 O O   . TRP B 1 449 ? 131.038 99.550  148.049 1.00 178.59 ?  449  TRP B O   1 
ATOM   6100 C CB  . TRP B 1 449 ? 129.377 102.025 146.934 1.00 178.59 ?  449  TRP B CB  1 
ATOM   6101 C CG  . TRP B 1 449 ? 128.515 102.470 145.815 1.00 178.59 ?  449  TRP B CG  1 
ATOM   6102 C CD1 . TRP B 1 449 ? 127.371 103.200 145.906 1.00 178.59 ?  449  TRP B CD1 1 
ATOM   6103 C CD2 . TRP B 1 449 ? 128.710 102.200 144.423 1.00 178.59 ?  449  TRP B CD2 1 
ATOM   6104 N NE1 . TRP B 1 449 ? 126.846 103.410 144.661 1.00 178.59 ?  449  TRP B NE1 1 
ATOM   6105 C CE2 . TRP B 1 449 ? 127.649 102.809 143.731 1.00 178.59 ?  449  TRP B CE2 1 
ATOM   6106 C CE3 . TRP B 1 449 ? 129.687 101.516 143.695 1.00 178.59 ?  449  TRP B CE3 1 
ATOM   6107 C CZ2 . TRP B 1 449 ? 127.530 102.747 142.348 1.00 178.59 ?  449  TRP B CZ2 1 
ATOM   6108 C CZ3 . TRP B 1 449 ? 129.567 101.455 142.326 1.00 178.59 ?  449  TRP B CZ3 1 
ATOM   6109 C CH2 . TRP B 1 449 ? 128.498 102.069 141.666 1.00 178.59 ?  449  TRP B CH2 1 
ATOM   6110 N N   . ILE B 1 450 ? 129.726 100.324 149.677 1.00 153.23 ?  450  ILE B N   1 
ATOM   6111 C CA  . ILE B 1 450 ? 130.609 99.815  150.706 1.00 153.23 ?  450  ILE B CA  1 
ATOM   6112 C C   . ILE B 1 450 ? 130.253 98.358  150.952 1.00 153.23 ?  450  ILE B C   1 
ATOM   6113 O O   . ILE B 1 450 ? 129.158 98.040  151.413 1.00 153.23 ?  450  ILE B O   1 
ATOM   6114 C CB  . ILE B 1 450 ? 130.584 100.685 151.985 1.00 153.23 ?  450  ILE B CB  1 
ATOM   6115 C CG1 . ILE B 1 450 ? 131.438 101.937 151.783 1.00 153.23 ?  450  ILE B CG1 1 
ATOM   6116 C CG2 . ILE B 1 450 ? 131.142 99.929  153.179 1.00 153.23 ?  450  ILE B CG2 1 
ATOM   6117 C CD1 . ILE B 1 450 ? 130.695 103.135 151.243 1.00 153.23 ?  450  ILE B CD1 1 
ATOM   6118 N N   . HIS B 1 451 ? 131.159 97.463  150.585 1.00 176.34 ?  451  HIS B N   1 
ATOM   6119 C CA  . HIS B 1 451 ? 130.930 96.047  150.806 1.00 176.34 ?  451  HIS B CA  1 
ATOM   6120 C C   . HIS B 1 451 ? 131.695 95.666  152.054 1.00 176.34 ?  451  HIS B C   1 
ATOM   6121 O O   . HIS B 1 451 ? 132.813 96.138  152.248 1.00 176.34 ?  451  HIS B O   1 
ATOM   6122 C CB  . HIS B 1 451 ? 131.424 95.233  149.605 1.00 176.34 ?  451  HIS B CB  1 
ATOM   6123 C CG  . HIS B 1 451 ? 131.103 93.775  149.691 1.00 176.34 ?  451  HIS B CG  1 
ATOM   6124 N ND1 . HIS B 1 451 ? 129.849 93.273  149.423 1.00 176.34 ?  451  HIS B ND1 1 
ATOM   6125 C CD2 . HIS B 1 451 ? 131.867 92.711  150.033 1.00 176.34 ?  451  HIS B CD2 1 
ATOM   6126 C CE1 . HIS B 1 451 ? 129.856 91.964  149.589 1.00 176.34 ?  451  HIS B CE1 1 
ATOM   6127 N NE2 . HIS B 1 451 ? 131.070 91.598  149.959 1.00 176.34 ?  451  HIS B NE2 1 
ATOM   6128 N N   . PRO B 1 452 ? 131.100 94.832  152.922 1.00 207.20 ?  452  PRO B N   1 
ATOM   6129 C CA  . PRO B 1 452 ? 131.775 94.364  154.135 1.00 207.20 ?  452  PRO B CA  1 
ATOM   6130 C C   . PRO B 1 452 ? 133.247 94.013  153.956 1.00 207.20 ?  452  PRO B C   1 
ATOM   6131 O O   . PRO B 1 452 ? 134.076 94.484  154.729 1.00 207.20 ?  452  PRO B O   1 
ATOM   6132 C CB  . PRO B 1 452 ? 130.994 93.097  154.491 1.00 207.20 ?  452  PRO B CB  1 
ATOM   6133 C CG  . PRO B 1 452 ? 129.716 93.153  153.701 1.00 207.20 ?  452  PRO B CG  1 
ATOM   6134 C CD  . PRO B 1 452 ? 129.686 94.436  152.925 1.00 207.20 ?  452  PRO B CD  1 
ATOM   6135 N N   . ARG B 1 453 ? 133.571 93.194  152.962 1.00 216.41 ?  453  ARG B N   1 
ATOM   6136 C CA  . ARG B 1 453 ? 134.949 92.773  152.759 1.00 216.41 ?  453  ARG B CA  1 
ATOM   6137 C C   . ARG B 1 453 ? 135.657 93.550  151.665 1.00 216.41 ?  453  ARG B C   1 
ATOM   6138 O O   . ARG B 1 453 ? 136.707 94.141  151.903 1.00 216.41 ?  453  ARG B O   1 
ATOM   6139 C CB  . ARG B 1 453 ? 134.998 91.281  152.444 1.00 216.41 ?  453  ARG B CB  1 
ATOM   6140 C CG  . ARG B 1 453 ? 133.869 90.478  153.065 1.00 216.41 ?  453  ARG B CG  1 
ATOM   6141 C CD  . ARG B 1 453 ? 133.187 89.609  152.025 1.00 216.41 ?  453  ARG B CD  1 
ATOM   6142 N NE  . ARG B 1 453 ? 133.960 89.547  150.789 1.00 216.41 ?  453  ARG B NE  1 
ATOM   6143 C CZ  . ARG B 1 453 ? 133.705 88.708  149.793 1.00 216.41 ?  453  ARG B CZ  1 
ATOM   6144 N NH1 . ARG B 1 453 ? 134.461 88.716  148.705 1.00 216.41 ?  453  ARG B NH1 1 
ATOM   6145 N NH2 . ARG B 1 453 ? 132.692 87.857  149.886 1.00 216.41 ?  453  ARG B NH2 1 
ATOM   6146 N N   . VAL B 1 454 ? 135.095 93.552  150.464 1.00 199.01 ?  454  VAL B N   1 
ATOM   6147 C CA  . VAL B 1 454 ? 135.735 94.223  149.336 1.00 199.01 ?  454  VAL B CA  1 
ATOM   6148 C C   . VAL B 1 454 ? 135.772 95.739  149.495 1.00 199.01 ?  454  VAL B C   1 
ATOM   6149 O O   . VAL B 1 454 ? 134.752 96.361  149.779 1.00 199.01 ?  454  VAL B O   1 
ATOM   6150 C CB  . VAL B 1 454 ? 135.051 93.824  148.014 1.00 199.01 ?  454  VAL B CB  1 
ATOM   6151 C CG1 . VAL B 1 454 ? 135.883 94.235  146.815 1.00 199.01 ?  454  VAL B CG1 1 
ATOM   6152 C CG2 . VAL B 1 454 ? 134.817 92.325  147.984 1.00 199.01 ?  454  VAL B CG2 1 
ATOM   6153 N N   . ASN B 1 455 ? 136.946 96.336  149.316 1.00 173.98 ?  455  ASN B N   1 
ATOM   6154 C CA  . ASN B 1 455 ? 137.087 97.786  149.419 1.00 173.98 ?  455  ASN B CA  1 
ATOM   6155 C C   . ASN B 1 455 ? 136.283 98.499  148.353 1.00 173.98 ?  455  ASN B C   1 
ATOM   6156 O O   . ASN B 1 455 ? 136.244 98.047  147.218 1.00 173.98 ?  455  ASN B O   1 
ATOM   6157 C CB  . ASN B 1 455 ? 138.561 98.169  149.281 1.00 173.98 ?  455  ASN B CB  1 
ATOM   6158 C CG  . ASN B 1 455 ? 138.801 99.659  149.428 1.00 173.98 ?  455  ASN B CG  1 
ATOM   6159 O OD1 . ASN B 1 455 ? 138.300 100.295 150.354 1.00 173.98 ?  455  ASN B OD1 1 
ATOM   6160 N ND2 . ASN B 1 455 ? 139.575 100.222 148.513 1.00 173.98 ?  455  ASN B ND2 1 
ATOM   6161 N N   . VAL B 1 456 ? 135.665 99.622  148.706 1.00 157.56 ?  456  VAL B N   1 
ATOM   6162 C CA  . VAL B 1 456 ? 134.879 100.405 147.752 1.00 157.56 ?  456  VAL B CA  1 
ATOM   6163 C C   . VAL B 1 456 ? 135.504 100.542 146.381 1.00 157.56 ?  456  VAL B C   1 
ATOM   6164 O O   . VAL B 1 456 ? 134.855 100.261 145.393 1.00 157.56 ?  456  VAL B O   1 
ATOM   6165 C CB  . VAL B 1 456 ? 134.619 101.822 148.273 1.00 157.56 ?  456  VAL B CB  1 
ATOM   6166 C CG1 . VAL B 1 456 ? 133.194 102.222 147.958 1.00 157.56 ?  456  VAL B CG1 1 
ATOM   6167 C CG2 . VAL B 1 456 ? 134.891 101.897 149.765 1.00 157.56 ?  456  VAL B CG2 1 
ATOM   6168 N N   . VAL B 1 457 ? 136.755 100.974 146.316 1.00 156.78 ?  457  VAL B N   1 
ATOM   6169 C CA  . VAL B 1 457 ? 137.437 101.164 145.041 1.00 156.78 ?  457  VAL B CA  1 
ATOM   6170 C C   . VAL B 1 457 ? 137.281 99.964  144.114 1.00 156.78 ?  457  VAL B C   1 
ATOM   6171 O O   . VAL B 1 457 ? 136.920 100.119 142.952 1.00 156.78 ?  457  VAL B O   1 
ATOM   6172 C CB  . VAL B 1 457 ? 138.921 101.523 145.272 1.00 156.78 ?  457  VAL B CB  1 
ATOM   6173 C CG1 . VAL B 1 457 ? 139.727 101.452 143.987 1.00 156.78 ?  457  VAL B CG1 1 
ATOM   6174 C CG2 . VAL B 1 457 ? 139.025 102.911 145.878 1.00 156.78 ?  457  VAL B CG2 1 
ATOM   6175 N N   . ILE B 1 458 ? 137.506 98.764  144.631 1.00 182.65 ?  458  ILE B N   1 
ATOM   6176 C CA  . ILE B 1 458 ? 137.383 97.567  143.815 1.00 182.65 ?  458  ILE B CA  1 
ATOM   6177 C C   . ILE B 1 458 ? 135.952 97.277  143.393 1.00 182.65 ?  458  ILE B C   1 
ATOM   6178 O O   . ILE B 1 458 ? 135.733 96.756  142.313 1.00 182.65 ?  458  ILE B O   1 
ATOM   6179 C CB  . ILE B 1 458 ? 137.981 96.343  144.517 1.00 182.65 ?  458  ILE B CB  1 
ATOM   6180 C CG1 . ILE B 1 458 ? 139.041 96.783  145.526 1.00 182.65 ?  458  ILE B CG1 1 
ATOM   6181 C CG2 . ILE B 1 458 ? 138.594 95.390  143.503 1.00 182.65 ?  458  ILE B CG2 1 
ATOM   6182 C CD1 . ILE B 1 458 ? 139.612 95.646  146.342 1.00 182.65 ?  458  ILE B CD1 1 
ATOM   6183 N N   . ILE B 1 459 ? 134.967 97.615  144.214 1.00 168.11 ?  459  ILE B N   1 
ATOM   6184 C CA  . ILE B 1 459 ? 133.585 97.432  143.774 1.00 168.11 ?  459  ILE B CA  1 
ATOM   6185 C C   . ILE B 1 459 ? 133.174 98.444  142.703 1.00 168.11 ?  459  ILE B C   1 
ATOM   6186 O O   . ILE B 1 459 ? 132.365 98.120  141.844 1.00 168.11 ?  459  ILE B O   1 
ATOM   6187 C CB  . ILE B 1 459 ? 132.562 97.302  144.941 1.00 168.11 ?  459  ILE B CB  1 
ATOM   6188 C CG1 . ILE B 1 459 ? 131.557 98.450  144.965 1.00 168.11 ?  459  ILE B CG1 1 
ATOM   6189 C CG2 . ILE B 1 459 ? 133.251 97.125  146.281 1.00 168.11 ?  459  ILE B CG2 1 
ATOM   6190 C CD1 . ILE B 1 459 ? 130.128 97.963  144.962 1.00 168.11 ?  459  ILE B CD1 1 
ATOM   6191 N N   . ILE B 1 460 ? 133.755 99.645  142.707 1.00 157.05 ?  460  ILE B N   1 
ATOM   6192 C CA  . ILE B 1 460 ? 133.465 100.609 141.647 1.00 157.05 ?  460  ILE B CA  1 
ATOM   6193 C C   . ILE B 1 460 ? 134.158 100.127 140.396 1.00 157.05 ?  460  ILE B C   1 
ATOM   6194 O O   . ILE B 1 460 ? 133.643 100.282 139.296 1.00 157.05 ?  460  ILE B O   1 
ATOM   6195 C CB  . ILE B 1 460 ? 133.941 102.039 141.971 1.00 157.05 ?  460  ILE B CB  1 
ATOM   6196 C CG1 . ILE B 1 460 ? 133.641 102.418 143.411 1.00 157.05 ?  460  ILE B CG1 1 
ATOM   6197 C CG2 . ILE B 1 460 ? 133.223 103.048 141.102 1.00 157.05 ?  460  ILE B CG2 1 
ATOM   6198 C CD1 . ILE B 1 460 ? 134.472 103.585 143.893 1.00 157.05 ?  460  ILE B CD1 1 
ATOM   6199 N N   . PHE B 1 461 ? 135.327 99.522  140.558 1.00 201.00 ?  461  PHE B N   1 
ATOM   6200 C CA  . PHE B 1 461 ? 136.054 98.974  139.424 1.00 201.00 ?  461  PHE B CA  1 
ATOM   6201 C C   . PHE B 1 461 ? 135.253 97.837  138.822 1.00 201.00 ?  461  PHE B C   1 
ATOM   6202 O O   . PHE B 1 461 ? 135.151 97.723  137.611 1.00 201.00 ?  461  PHE B O   1 
ATOM   6203 C CB  . PHE B 1 461 ? 137.432 98.498  139.887 1.00 201.00 ?  461  PHE B CB  1 
ATOM   6204 C CG  . PHE B 1 461 ? 138.128 97.588  138.925 1.00 201.00 ?  461  PHE B CG  1 
ATOM   6205 C CD1 . PHE B 1 461 ? 138.687 98.088  137.762 1.00 201.00 ?  461  PHE B CD1 1 
ATOM   6206 C CD2 . PHE B 1 461 ? 138.249 96.235  139.196 1.00 201.00 ?  461  PHE B CD2 1 
ATOM   6207 C CE1 . PHE B 1 461 ? 139.336 97.254  136.877 1.00 201.00 ?  461  PHE B CE1 1 
ATOM   6208 C CE2 . PHE B 1 461 ? 138.892 95.395  138.313 1.00 201.00 ?  461  PHE B CE2 1 
ATOM   6209 C CZ  . PHE B 1 461 ? 139.439 95.905  137.153 1.00 201.00 ?  461  PHE B CZ  1 
ATOM   6210 N N   . LEU B 1 462 ? 134.663 97.004  139.666 1.00 190.40 ?  462  LEU B N   1 
ATOM   6211 C CA  . LEU B 1 462 ? 133.899 95.877  139.170 1.00 190.40 ?  462  LEU B CA  1 
ATOM   6212 C C   . LEU B 1 462 ? 132.589 96.330  138.580 1.00 190.40 ?  462  LEU B C   1 
ATOM   6213 O O   . LEU B 1 462 ? 132.107 95.715  137.649 1.00 190.40 ?  462  LEU B O   1 
ATOM   6214 C CB  . LEU B 1 462 ? 133.666 94.852  140.266 1.00 190.40 ?  462  LEU B CB  1 
ATOM   6215 C CG  . LEU B 1 462 ? 134.469 93.560  140.177 1.00 190.40 ?  462  LEU B CG  1 
ATOM   6216 C CD1 . LEU B 1 462 ? 135.292 93.512  138.900 1.00 190.40 ?  462  LEU B CD1 1 
ATOM   6217 C CD2 . LEU B 1 462 ? 135.352 93.399  141.402 1.00 190.40 ?  462  LEU B CD2 1 
ATOM   6218 N N   . PHE B 1 463 ? 132.005 97.401  139.103 1.00 168.22 ?  463  PHE B N   1 
ATOM   6219 C CA  . PHE B 1 463 ? 130.796 97.951  138.513 1.00 168.22 ?  463  PHE B CA  1 
ATOM   6220 C C   . PHE B 1 463 ? 131.172 98.371  137.119 1.00 168.22 ?  463  PHE B C   1 
ATOM   6221 O O   . PHE B 1 463 ? 130.523 97.990  136.170 1.00 168.22 ?  463  PHE B O   1 
ATOM   6222 C CB  . PHE B 1 463 ? 130.313 99.158  139.324 1.00 168.22 ?  463  PHE B CB  1 
ATOM   6223 C CG  . PHE B 1 463 ? 129.126 99.880  138.737 1.00 168.22 ?  463  PHE B CG  1 
ATOM   6224 C CD1 . PHE B 1 463 ? 127.841 99.444  138.981 1.00 168.22 ?  463  PHE B CD1 1 
ATOM   6225 C CD2 . PHE B 1 463 ? 129.295 101.027 137.986 1.00 168.22 ?  463  PHE B CD2 1 
ATOM   6226 C CE1 . PHE B 1 463 ? 126.751 100.115 138.469 1.00 168.22 ?  463  PHE B CE1 1 
ATOM   6227 C CE2 . PHE B 1 463 ? 128.213 101.702 137.460 1.00 168.22 ?  463  PHE B CE2 1 
ATOM   6228 C CZ  . PHE B 1 463 ? 126.938 101.246 137.704 1.00 168.22 ?  463  PHE B CZ  1 
ATOM   6229 N N   . PHE B 1 464 ? 132.242 99.141  136.993 1.00 193.47 ?  464  PHE B N   1 
ATOM   6230 C CA  . PHE B 1 464 ? 132.673 99.621  135.695 1.00 193.47 ?  464  PHE B CA  1 
ATOM   6231 C C   . PHE B 1 464 ? 132.920 98.493  134.710 1.00 193.47 ?  464  PHE B C   1 
ATOM   6232 O O   . PHE B 1 464 ? 132.445 98.544  133.591 1.00 193.47 ?  464  PHE B O   1 
ATOM   6233 C CB  . PHE B 1 464 ? 133.927 100.485 135.840 1.00 193.47 ?  464  PHE B CB  1 
ATOM   6234 C CG  . PHE B 1 464 ? 134.428 101.039 134.543 1.00 193.47 ?  464  PHE B CG  1 
ATOM   6235 C CD1 . PHE B 1 464 ? 133.747 102.054 133.911 1.00 193.47 ?  464  PHE B CD1 1 
ATOM   6236 C CD2 . PHE B 1 464 ? 135.573 100.536 133.952 1.00 193.47 ?  464  PHE B CD2 1 
ATOM   6237 C CE1 . PHE B 1 464 ? 134.191 102.567 132.712 1.00 193.47 ?  464  PHE B CE1 1 
ATOM   6238 C CE2 . PHE B 1 464 ? 136.021 101.042 132.752 1.00 193.47 ?  464  PHE B CE2 1 
ATOM   6239 C CZ  . PHE B 1 464 ? 135.328 102.061 132.134 1.00 193.47 ?  464  PHE B CZ  1 
ATOM   6240 N N   . VAL B 1 465 ? 133.666 97.477  135.119 1.00 202.93 ?  465  VAL B N   1 
ATOM   6241 C CA  . VAL B 1 465 ? 133.985 96.372  134.229 1.00 202.93 ?  465  VAL B CA  1 
ATOM   6242 C C   . VAL B 1 465 ? 132.733 95.613  133.835 1.00 202.93 ?  465  VAL B C   1 
ATOM   6243 O O   . VAL B 1 465 ? 132.487 95.372  132.651 1.00 202.93 ?  465  VAL B O   1 
ATOM   6244 C CB  . VAL B 1 465 ? 135.028 95.437  134.876 1.00 202.93 ?  465  VAL B CB  1 
ATOM   6245 C CG1 . VAL B 1 465 ? 135.100 94.092  134.169 1.00 202.93 ?  465  VAL B CG1 1 
ATOM   6246 C CG2 . VAL B 1 465 ? 136.388 96.103  134.855 1.00 202.93 ?  465  VAL B CG2 1 
ATOM   6247 N N   . MET B 1 466 ? 131.916 95.261  134.814 1.00 206.60 ?  466  MET B N   1 
ATOM   6248 C CA  . MET B 1 466 ? 130.726 94.490  134.526 1.00 206.60 ?  466  MET B CA  1 
ATOM   6249 C C   . MET B 1 466 ? 129.777 95.269  133.659 1.00 206.60 ?  466  MET B C   1 
ATOM   6250 O O   . MET B 1 466 ? 129.318 94.777  132.645 1.00 206.60 ?  466  MET B O   1 
ATOM   6251 C CB  . MET B 1 466 ? 130.041 94.058  135.806 1.00 206.60 ?  466  MET B CB  1 
ATOM   6252 C CG  . MET B 1 466 ? 130.231 92.590  136.136 1.00 206.60 ?  466  MET B CG  1 
ATOM   6253 S SD  . MET B 1 466 ? 131.965 92.136  136.283 1.00 206.60 ?  466  MET B SD  1 
ATOM   6254 C CE  . MET B 1 466 ? 131.923 90.471  135.630 1.00 206.60 ?  466  MET B CE  1 
ATOM   6255 N N   . LYS B 1 467 ? 129.506 96.507  134.035 1.00 171.12 ?  467  LYS B N   1 
ATOM   6256 C CA  . LYS B 1 467 ? 128.584 97.325  133.273 1.00 171.12 ?  467  LYS B CA  1 
ATOM   6257 C C   . LYS B 1 467 ? 129.132 97.733  131.926 1.00 171.12 ?  467  LYS B C   1 
ATOM   6258 O O   . LYS B 1 467 ? 128.375 98.150  131.082 1.00 171.12 ?  467  LYS B O   1 
ATOM   6259 C CB  . LYS B 1 467 ? 128.132 98.541  134.074 1.00 171.12 ?  467  LYS B CB  1 
ATOM   6260 C CG  . LYS B 1 467 ? 127.147 98.210  135.176 1.00 171.12 ?  467  LYS B CG  1 
ATOM   6261 C CD  . LYS B 1 467 ? 125.724 98.508  134.747 1.00 171.12 ?  467  LYS B CD  1 
ATOM   6262 C CE  . LYS B 1 467 ? 124.724 97.874  135.696 1.00 171.12 ?  467  LYS B CE  1 
ATOM   6263 N NZ  . LYS B 1 467 ? 123.891 96.849  135.010 1.00 171.12 ?  467  LYS B NZ  1 
ATOM   6264 N N   . PHE B 1 468 ? 130.435 97.623  131.708 1.00 195.61 ?  468  PHE B N   1 
ATOM   6265 C CA  . PHE B 1 468 ? 130.985 97.911  130.394 1.00 195.61 ?  468  PHE B CA  1 
ATOM   6266 C C   . PHE B 1 468 ? 130.446 96.892  129.424 1.00 195.61 ?  468  PHE B C   1 
ATOM   6267 O O   . PHE B 1 468 ? 129.827 97.253  128.430 1.00 195.61 ?  468  PHE B O   1 
ATOM   6268 C CB  . PHE B 1 468 ? 132.509 97.869  130.397 1.00 195.61 ?  468  PHE B CB  1 
ATOM   6269 C CG  . PHE B 1 468 ? 133.147 98.832  129.446 1.00 195.61 ?  468  PHE B CG  1 
ATOM   6270 C CD1 . PHE B 1 468 ? 133.151 100.187 129.712 1.00 195.61 ?  468  PHE B CD1 1 
ATOM   6271 C CD2 . PHE B 1 468 ? 133.758 98.381  128.292 1.00 195.61 ?  468  PHE B CD2 1 
ATOM   6272 C CE1 . PHE B 1 468 ? 133.740 101.079 128.840 1.00 195.61 ?  468  PHE B CE1 1 
ATOM   6273 C CE2 . PHE B 1 468 ? 134.349 99.266  127.415 1.00 195.61 ?  468  PHE B CE2 1 
ATOM   6274 C CZ  . PHE B 1 468 ? 134.344 100.616 127.692 1.00 195.61 ?  468  PHE B CZ  1 
ATOM   6275 N N   . TRP B 1 469 ? 130.667 95.613  129.717 1.00 191.84 ?  469  TRP B N   1 
ATOM   6276 C CA  . TRP B 1 469 ? 130.208 94.569  128.816 1.00 191.84 ?  469  TRP B CA  1 
ATOM   6277 C C   . TRP B 1 469 ? 128.700 94.472  128.793 1.00 191.84 ?  469  TRP B C   1 
ATOM   6278 O O   . TRP B 1 469 ? 128.121 94.186  127.757 1.00 191.84 ?  469  TRP B O   1 
ATOM   6279 C CB  . TRP B 1 469 ? 130.867 93.199  129.082 1.00 191.84 ?  469  TRP B CB  1 
ATOM   6280 C CG  . TRP B 1 469 ? 130.535 92.501  130.379 1.00 191.84 ?  469  TRP B CG  1 
ATOM   6281 C CD1 . TRP B 1 469 ? 131.293 92.489  131.506 1.00 191.84 ?  469  TRP B CD1 1 
ATOM   6282 C CD2 . TRP B 1 469 ? 129.393 91.667  130.658 1.00 191.84 ?  469  TRP B CD2 1 
ATOM   6283 N NE1 . TRP B 1 469 ? 130.689 91.734  132.478 1.00 191.84 ?  469  TRP B NE1 1 
ATOM   6284 C CE2 . TRP B 1 469 ? 129.521 91.221  131.985 1.00 191.84 ?  469  TRP B CE2 1 
ATOM   6285 C CE3 . TRP B 1 469 ? 128.272 91.270  129.920 1.00 191.84 ?  469  TRP B CE3 1 
ATOM   6286 C CZ2 . TRP B 1 469 ? 128.577 90.397  132.590 1.00 191.84 ?  469  TRP B CZ2 1 
ATOM   6287 C CZ3 . TRP B 1 469 ? 127.331 90.461  130.526 1.00 191.84 ?  469  TRP B CZ3 1 
ATOM   6288 C CH2 . TRP B 1 469 ? 127.491 90.029  131.846 1.00 191.84 ?  469  TRP B CH2 1 
ATOM   6289 N N   . MET B 1 470 ? 128.058 94.719  129.926 1.00 169.44 ?  470  MET B N   1 
ATOM   6290 C CA  . MET B 1 470 ? 126.609 94.680  129.987 1.00 169.44 ?  470  MET B CA  1 
ATOM   6291 C C   . MET B 1 470 ? 126.029 95.715  129.059 1.00 169.44 ?  470  MET B C   1 
ATOM   6292 O O   . MET B 1 470 ? 125.136 95.422  128.282 1.00 169.44 ?  470  MET B O   1 
ATOM   6293 C CB  . MET B 1 470 ? 126.131 94.945  131.399 1.00 169.44 ?  470  MET B CB  1 
ATOM   6294 C CG  . MET B 1 470 ? 126.221 93.749  132.313 1.00 169.44 ?  470  MET B CG  1 
ATOM   6295 S SD  . MET B 1 470 ? 126.086 94.248  134.029 1.00 169.44 ?  470  MET B SD  1 
ATOM   6296 C CE  . MET B 1 470 ? 126.556 92.718  134.806 1.00 169.44 ?  470  MET B CE  1 
ATOM   6297 N N   . SER B 1 471 ? 126.551 96.933  129.121 1.00 148.38 ?  471  SER B N   1 
ATOM   6298 C CA  . SER B 1 471 ? 126.066 97.999  128.263 1.00 148.38 ?  471  SER B CA  1 
ATOM   6299 C C   . SER B 1 471 ? 126.399 97.751  126.804 1.00 148.38 ?  471  SER B C   1 
ATOM   6300 O O   . SER B 1 471 ? 125.634 98.122  125.933 1.00 148.38 ?  471  SER B O   1 
ATOM   6301 C CB  . SER B 1 471 ? 126.640 99.333  128.709 1.00 148.38 ?  471  SER B CB  1 
ATOM   6302 O OG  . SER B 1 471 ? 126.290 99.615  130.048 1.00 148.38 ?  471  SER B OG  1 
ATOM   6303 N N   . ILE B 1 472 ? 127.529 97.118  126.523 1.00 186.70 ?  472  ILE B N   1 
ATOM   6304 C CA  . ILE B 1 472 ? 127.878 96.792  125.146 1.00 186.70 ?  472  ILE B CA  1 
ATOM   6305 C C   . ILE B 1 472 ? 126.843 95.850  124.533 1.00 186.70 ?  472  ILE B C   1 
ATOM   6306 O O   . ILE B 1 472 ? 126.381 96.083  123.420 1.00 186.70 ?  472  ILE B O   1 
ATOM   6307 C CB  . ILE B 1 472 ? 129.348 96.293  125.010 1.00 186.70 ?  472  ILE B CB  1 
ATOM   6308 C CG1 . ILE B 1 472 ? 130.265 97.460  124.659 1.00 186.70 ?  472  ILE B CG1 1 
ATOM   6309 C CG2 . ILE B 1 472 ? 129.514 95.247  123.926 1.00 186.70 ?  472  ILE B CG2 1 
ATOM   6310 C CD1 . ILE B 1 472 ? 131.604 97.428  125.349 1.00 186.70 ?  472  ILE B CD1 1 
ATOM   6311 N N   . VAL B 1 473 ? 126.421 94.828  125.267 1.00 198.17 ?  473  VAL B N   1 
ATOM   6312 C CA  . VAL B 1 473 ? 125.495 93.852  124.701 1.00 198.17 ?  473  VAL B CA  1 
ATOM   6313 C C   . VAL B 1 473 ? 124.018 94.204  124.825 1.00 198.17 ?  473  VAL B C   1 
ATOM   6314 O O   . VAL B 1 473 ? 123.186 93.609  124.139 1.00 198.17 ?  473  VAL B O   1 
ATOM   6315 C CB  . VAL B 1 473 ? 125.752 92.433  125.250 1.00 198.17 ?  473  VAL B CB  1 
ATOM   6316 C CG1 . VAL B 1 473 ? 127.160 91.982  124.905 1.00 198.17 ?  473  VAL B CG1 1 
ATOM   6317 C CG2 . VAL B 1 473 ? 125.526 92.370  126.750 1.00 198.17 ?  473  VAL B CG2 1 
ATOM   6318 N N   . ALA B 1 474 ? 123.690 95.167  125.676 1.00 179.15 ?  474  ALA B N   1 
ATOM   6319 C CA  . ALA B 1 474 ? 122.306 95.581  125.843 1.00 179.15 ?  474  ALA B CA  1 
ATOM   6320 C C   . ALA B 1 474 ? 121.974 96.654  124.834 1.00 179.15 ?  474  ALA B C   1 
ATOM   6321 O O   . ALA B 1 474 ? 120.808 96.926  124.565 1.00 179.15 ?  474  ALA B O   1 
ATOM   6322 C CB  . ALA B 1 474 ? 122.072 96.088  127.242 1.00 179.15 ?  474  ALA B CB  1 
ATOM   6323 N N   . THR B 1 475 ? 122.998 97.273  124.261 1.00 160.89 ?  475  THR B N   1 
ATOM   6324 C CA  . THR B 1 475 ? 122.765 98.267  123.224 1.00 160.89 ?  475  THR B CA  1 
ATOM   6325 C C   . THR B 1 475 ? 122.789 97.564  121.881 1.00 160.89 ?  475  THR B C   1 
ATOM   6326 O O   . THR B 1 475 ? 122.559 98.187  120.849 1.00 160.89 ?  475  THR B O   1 
ATOM   6327 C CB  . THR B 1 475 ? 123.796 99.399  123.266 1.00 160.89 ?  475  THR B CB  1 
ATOM   6328 O OG1 . THR B 1 475 ? 125.112 98.846  123.359 1.00 160.89 ?  475  THR B OG1 1 
ATOM   6329 C CG2 . THR B 1 475 ? 123.545 100.292 124.459 1.00 160.89 ?  475  THR B CG2 1 
ATOM   6330 N N   . THR B 1 476 ? 123.054 96.263  121.891 1.00 196.92 ?  476  THR B N   1 
ATOM   6331 C CA  . THR B 1 476 ? 123.082 95.486  120.662 1.00 196.92 ?  476  THR B CA  1 
ATOM   6332 C C   . THR B 1 476 ? 121.760 94.737  120.573 1.00 196.92 ?  476  THR B C   1 
ATOM   6333 O O   . THR B 1 476 ? 121.368 94.251  119.512 1.00 196.92 ?  476  THR B O   1 
ATOM   6334 C CB  . THR B 1 476 ? 124.308 94.557  120.676 1.00 196.92 ?  476  THR B CB  1 
ATOM   6335 O OG1 . THR B 1 476 ? 125.478 95.355  120.874 1.00 196.92 ?  476  THR B OG1 1 
ATOM   6336 C CG2 . THR B 1 476 ? 124.463 93.786  119.378 1.00 196.92 ?  476  THR B CG2 1 
ATOM   6337 N N   . MET B 1 477 ? 121.033 94.685  121.679 1.00 192.79 ?  477  MET B N   1 
ATOM   6338 C CA  . MET B 1 477 ? 119.745 94.002  121.703 1.00 192.79 ?  477  MET B CA  1 
ATOM   6339 C C   . MET B 1 477 ? 118.751 94.637  120.740 1.00 192.79 ?  477  MET B C   1 
ATOM   6340 O O   . MET B 1 477 ? 118.775 95.851  120.536 1.00 192.79 ?  477  MET B O   1 
ATOM   6341 C CB  . MET B 1 477 ? 119.189 94.020  123.125 1.00 192.79 ?  477  MET B CB  1 
ATOM   6342 C CG  . MET B 1 477 ? 119.626 92.849  123.982 1.00 192.79 ?  477  MET B CG  1 
ATOM   6343 S SD  . MET B 1 477 ? 118.872 92.882  125.618 1.00 192.79 ?  477  MET B SD  1 
ATOM   6344 C CE  . MET B 1 477 ? 118.472 94.616  125.785 1.00 192.79 ?  477  MET B CE  1 
ATOM   6345 N N   . PRO B 1 478 ? 117.858 93.827  120.140 1.00 211.25 ?  478  PRO B N   1 
ATOM   6346 C CA  . PRO B 1 478 ? 116.861 94.338  119.183 1.00 211.25 ?  478  PRO B CA  1 
ATOM   6347 C C   . PRO B 1 478 ? 115.685 95.079  119.808 1.00 211.25 ?  478  PRO B C   1 
ATOM   6348 O O   . PRO B 1 478 ? 114.544 94.805  119.449 1.00 211.25 ?  478  PRO B O   1 
ATOM   6349 C CB  . PRO B 1 478 ? 116.350 93.067  118.509 1.00 211.25 ?  478  PRO B CB  1 
ATOM   6350 C CG  . PRO B 1 478 ? 116.587 91.988  119.501 1.00 211.25 ?  478  PRO B CG  1 
ATOM   6351 C CD  . PRO B 1 478 ? 117.864 92.356  120.191 1.00 211.25 ?  478  PRO B CD  1 
ATOM   6352 N N   . ILE B 1 479 ? 115.948 96.000  120.724 1.00 201.13 ?  479  ILE B N   1 
ATOM   6353 C CA  . ILE B 1 479 ? 114.901 96.757  121.382 1.00 201.13 ?  479  ILE B CA  1 
ATOM   6354 C C   . ILE B 1 479 ? 115.288 98.209  121.149 1.00 201.13 ?  479  ILE B C   1 
ATOM   6355 O O   . ILE B 1 479 ? 116.391 98.470  120.689 1.00 201.13 ?  479  ILE B O   1 
ATOM   6356 C CB  . ILE B 1 479 ? 114.852 96.412  122.897 1.00 201.13 ?  479  ILE B CB  1 
ATOM   6357 C CG1 . ILE B 1 479 ? 116.030 97.024  123.653 1.00 201.13 ?  479  ILE B CG1 1 
ATOM   6358 C CG2 . ILE B 1 479 ? 114.836 94.911  123.135 1.00 201.13 ?  479  ILE B CG2 1 
ATOM   6359 C CD1 . ILE B 1 479 ? 115.622 97.649  124.967 1.00 201.13 ?  479  ILE B CD1 1 
ATOM   6360 N N   . PRO B 1 480 ? 114.379 99.167  121.400 1.00 227.50 ?  480  PRO B N   1 
ATOM   6361 C CA  . PRO B 1 480 ? 114.816 100.563 121.291 1.00 227.50 ?  480  PRO B CA  1 
ATOM   6362 C C   . PRO B 1 480 ? 115.821 100.857 122.393 1.00 227.50 ?  480  PRO B C   1 
ATOM   6363 O O   . PRO B 1 480 ? 115.436 100.859 123.558 1.00 227.50 ?  480  PRO B O   1 
ATOM   6364 C CB  . PRO B 1 480 ? 113.544 101.358 121.559 1.00 227.50 ?  480  PRO B CB  1 
ATOM   6365 C CG  . PRO B 1 480 ? 112.429 100.430 121.306 1.00 227.50 ?  480  PRO B CG  1 
ATOM   6366 C CD  . PRO B 1 480 ? 112.929 99.056  121.616 1.00 227.50 ?  480  PRO B CD  1 
ATOM   6367 N N   . CYS B 1 481 ? 117.080 101.093 122.050 1.00 191.72 ?  481  CYS B N   1 
ATOM   6368 C CA  . CYS B 1 481 ? 118.102 101.300 123.066 1.00 191.72 ?  481  CYS B CA  1 
ATOM   6369 C C   . CYS B 1 481 ? 119.050 102.416 122.699 1.00 191.72 ?  481  CYS B C   1 
ATOM   6370 O O   . CYS B 1 481 ? 119.452 102.531 121.556 1.00 191.72 ?  481  CYS B O   1 
ATOM   6371 C CB  . CYS B 1 481 ? 118.902 100.015 123.285 1.00 191.72 ?  481  CYS B CB  1 
ATOM   6372 S SG  . CYS B 1 481 ? 119.372 99.143  121.777 1.00 191.72 ?  481  CYS B SG  1 
ATOM   6373 N N   . GLY B 1 482 ? 119.425 103.235 123.669 1.00 186.76 ?  482  GLY B N   1 
ATOM   6374 C CA  . GLY B 1 482 ? 120.370 104.302 123.414 1.00 186.76 ?  482  GLY B CA  1 
ATOM   6375 C C   . GLY B 1 482 ? 121.681 104.050 124.111 1.00 186.76 ?  482  GLY B C   1 
ATOM   6376 O O   . GLY B 1 482 ? 121.804 103.097 124.874 1.00 186.76 ?  482  GLY B O   1 
ATOM   6377 N N   . GLY B 1 483 ? 122.663 104.904 123.867 1.00 205.56 ?  483  GLY B N   1 
ATOM   6378 C CA  . GLY B 1 483 ? 123.972 104.714 124.458 1.00 205.56 ?  483  GLY B CA  1 
ATOM   6379 C C   . GLY B 1 483 ? 124.388 105.704 125.523 1.00 205.56 ?  483  GLY B C   1 
ATOM   6380 O O   . GLY B 1 483 ? 125.218 105.364 126.342 1.00 205.56 ?  483  GLY B O   1 
ATOM   6381 N N   . PHE B 1 484 ? 123.825 106.909 125.526 1.00 180.54 ?  484  PHE B N   1 
ATOM   6382 C CA  . PHE B 1 484 ? 124.222 107.944 126.484 1.00 180.54 ?  484  PHE B CA  1 
ATOM   6383 C C   . PHE B 1 484 ? 124.206 107.452 127.901 1.00 180.54 ?  484  PHE B C   1 
ATOM   6384 O O   . PHE B 1 484 ? 125.240 107.380 128.523 1.00 180.54 ?  484  PHE B O   1 
ATOM   6385 C CB  . PHE B 1 484 ? 123.284 109.136 126.417 1.00 180.54 ?  484  PHE B CB  1 
ATOM   6386 C CG  . PHE B 1 484 ? 123.878 110.428 126.888 1.00 180.54 ?  484  PHE B CG  1 
ATOM   6387 C CD1 . PHE B 1 484 ? 123.794 110.805 128.218 1.00 180.54 ?  484  PHE B CD1 1 
ATOM   6388 C CD2 . PHE B 1 484 ? 124.478 111.288 125.992 1.00 180.54 ?  484  PHE B CD2 1 
ATOM   6389 C CE1 . PHE B 1 484 ? 124.317 112.005 128.645 1.00 180.54 ?  484  PHE B CE1 1 
ATOM   6390 C CE2 . PHE B 1 484 ? 125.006 112.487 126.415 1.00 180.54 ?  484  PHE B CE2 1 
ATOM   6391 C CZ  . PHE B 1 484 ? 124.927 112.846 127.744 1.00 180.54 ?  484  PHE B CZ  1 
ATOM   6392 N N   . MET B 1 485 ? 123.027 107.161 128.435 1.00 207.53 ?  485  MET B N   1 
ATOM   6393 C CA  . MET B 1 485 ? 122.925 106.765 129.837 1.00 207.53 ?  485  MET B CA  1 
ATOM   6394 C C   . MET B 1 485 ? 123.807 105.562 130.209 1.00 207.53 ?  485  MET B C   1 
ATOM   6395 O O   . MET B 1 485 ? 124.475 105.613 131.229 1.00 207.53 ?  485  MET B O   1 
ATOM   6396 C CB  . MET B 1 485 ? 121.467 106.551 130.246 1.00 207.53 ?  485  MET B CB  1 
ATOM   6397 C CG  . MET B 1 485 ? 120.783 107.813 130.736 1.00 207.53 ?  485  MET B CG  1 
ATOM   6398 S SD  . MET B 1 485 ? 121.297 108.233 132.409 1.00 207.53 ?  485  MET B SD  1 
ATOM   6399 C CE  . MET B 1 485 ? 120.618 106.843 133.310 1.00 207.53 ?  485  MET B CE  1 
ATOM   6400 N N   . PRO B 1 486 ? 123.806 104.461 129.407 1.00 177.21 ?  486  PRO B N   1 
ATOM   6401 C CA  . PRO B 1 486 ? 124.740 103.400 129.795 1.00 177.21 ?  486  PRO B CA  1 
ATOM   6402 C C   . PRO B 1 486 ? 126.175 103.903 129.966 1.00 177.21 ?  486  PRO B C   1 
ATOM   6403 O O   . PRO B 1 486 ? 126.791 103.605 130.978 1.00 177.21 ?  486  PRO B O   1 
ATOM   6404 C CB  . PRO B 1 486 ? 124.656 102.442 128.620 1.00 177.21 ?  486  PRO B CB  1 
ATOM   6405 C CG  . PRO B 1 486 ? 123.260 102.558 128.151 1.00 177.21 ?  486  PRO B CG  1 
ATOM   6406 C CD  . PRO B 1 486 ? 122.830 103.968 128.413 1.00 177.21 ?  486  PRO B CD  1 
ATOM   6407 N N   . VAL B 1 487 ? 126.690 104.670 129.014 1.00 174.21 ?  487  VAL B N   1 
ATOM   6408 C CA  . VAL B 1 487 ? 128.046 105.210 129.091 1.00 174.21 ?  487  VAL B CA  1 
ATOM   6409 C C   . VAL B 1 487 ? 128.172 106.307 130.148 1.00 174.21 ?  487  VAL B C   1 
ATOM   6410 O O   . VAL B 1 487 ? 129.244 106.528 130.701 1.00 174.21 ?  487  VAL B O   1 
ATOM   6411 C CB  . VAL B 1 487 ? 128.500 105.680 127.690 1.00 174.21 ?  487  VAL B CB  1 
ATOM   6412 C CG1 . VAL B 1 487 ? 129.954 106.075 127.683 1.00 174.21 ?  487  VAL B CG1 1 
ATOM   6413 C CG2 . VAL B 1 487 ? 128.314 104.559 126.691 1.00 174.21 ?  487  VAL B CG2 1 
ATOM   6414 N N   . PHE B 1 488 ? 127.082 106.985 130.459 1.00 179.03 ?  488  PHE B N   1 
ATOM   6415 C CA  . PHE B 1 488 ? 127.086 108.005 131.497 1.00 179.03 ?  488  PHE B CA  1 
ATOM   6416 C C   . PHE B 1 488 ? 127.368 107.357 132.838 1.00 179.03 ?  488  PHE B C   1 
ATOM   6417 O O   . PHE B 1 488 ? 128.196 107.841 133.593 1.00 179.03 ?  488  PHE B O   1 
ATOM   6418 C CB  . PHE B 1 488 ? 125.716 108.662 131.533 1.00 179.03 ?  488  PHE B CB  1 
ATOM   6419 C CG  . PHE B 1 488 ? 125.681 110.000 132.187 1.00 179.03 ?  488  PHE B CG  1 
ATOM   6420 C CD1 . PHE B 1 488 ? 126.105 111.121 131.509 1.00 179.03 ?  488  PHE B CD1 1 
ATOM   6421 C CD2 . PHE B 1 488 ? 125.181 110.143 133.467 1.00 179.03 ?  488  PHE B CD2 1 
ATOM   6422 C CE1 . PHE B 1 488 ? 126.046 112.362 132.099 1.00 179.03 ?  488  PHE B CE1 1 
ATOM   6423 C CE2 . PHE B 1 488 ? 125.123 111.380 134.066 1.00 179.03 ?  488  PHE B CE2 1 
ATOM   6424 C CZ  . PHE B 1 488 ? 125.557 112.491 133.383 1.00 179.03 ?  488  PHE B CZ  1 
ATOM   6425 N N   . VAL B 1 489 ? 126.689 106.251 133.135 1.00 173.69 ?  489  VAL B N   1 
ATOM   6426 C CA  . VAL B 1 489 ? 126.922 105.551 134.394 1.00 173.69 ?  489  VAL B CA  1 
ATOM   6427 C C   . VAL B 1 489 ? 128.318 104.955 134.433 1.00 173.69 ?  489  VAL B C   1 
ATOM   6428 O O   . VAL B 1 489 ? 128.918 104.855 135.497 1.00 173.69 ?  489  VAL B O   1 
ATOM   6429 C CB  . VAL B 1 489 ? 125.824 104.506 134.752 1.00 173.69 ?  489  VAL B CB  1 
ATOM   6430 C CG1 . VAL B 1 489 ? 124.441 104.979 134.363 1.00 173.69 ?  489  VAL B CG1 1 
ATOM   6431 C CG2 . VAL B 1 489 ? 126.110 103.118 134.200 1.00 173.69 ?  489  VAL B CG2 1 
ATOM   6432 N N   . LEU B 1 490 ? 128.857 104.605 133.272 1.00 175.84 ?  490  LEU B N   1 
ATOM   6433 C CA  . LEU B 1 490 ? 130.184 104.033 133.207 1.00 175.84 ?  490  LEU B CA  1 
ATOM   6434 C C   . LEU B 1 490 ? 131.220 105.082 133.504 1.00 175.84 ?  490  LEU B C   1 
ATOM   6435 O O   . LEU B 1 490 ? 132.173 104.832 134.219 1.00 175.84 ?  490  LEU B O   1 
ATOM   6436 C CB  . LEU B 1 490 ? 130.412 103.445 131.826 1.00 175.84 ?  490  LEU B CB  1 
ATOM   6437 C CG  . LEU B 1 490 ? 129.731 102.098 131.659 1.00 175.84 ?  490  LEU B CG  1 
ATOM   6438 C CD1 . LEU B 1 490 ? 129.792 101.628 130.219 1.00 175.84 ?  490  LEU B CD1 1 
ATOM   6439 C CD2 . LEU B 1 490 ? 130.399 101.122 132.599 1.00 175.84 ?  490  LEU B CD2 1 
ATOM   6440 N N   . GLY B 1 491 ? 131.030 106.274 132.968 1.00 201.49 ?  491  GLY B N   1 
ATOM   6441 C CA  . GLY B 1 491 ? 131.964 107.341 133.209 1.00 201.49 ?  491  GLY B CA  1 
ATOM   6442 C C   . GLY B 1 491 ? 131.882 107.832 134.617 1.00 201.49 ?  491  GLY B C   1 
ATOM   6443 O O   . GLY B 1 491 ? 132.883 108.219 135.193 1.00 201.49 ?  491  GLY B O   1 
ATOM   6444 N N   . ALA B 1 492 ? 130.689 107.825 135.184 1.00 210.27 ?  492  ALA B N   1 
ATOM   6445 C CA  . ALA B 1 492 ? 130.534 108.227 136.561 1.00 210.27 ?  492  ALA B CA  1 
ATOM   6446 C C   . ALA B 1 492 ? 131.285 107.254 137.435 1.00 210.27 ?  492  ALA B C   1 
ATOM   6447 O O   . ALA B 1 492 ? 131.946 107.659 138.371 1.00 210.27 ?  492  ALA B O   1 
ATOM   6448 C CB  . ALA B 1 492 ? 129.069 108.280 136.926 1.00 210.27 ?  492  ALA B CB  1 
ATOM   6449 N N   . ALA B 1 493 ? 131.213 105.968 137.120 1.00 201.74 ?  493  ALA B N   1 
ATOM   6450 C CA  . ALA B 1 493 ? 131.959 104.970 137.865 1.00 201.74 ?  493  ALA B CA  1 
ATOM   6451 C C   . ALA B 1 493 ? 133.448 105.168 137.726 1.00 201.74 ?  493  ALA B C   1 
ATOM   6452 O O   . ALA B 1 493 ? 134.170 105.131 138.706 1.00 201.74 ?  493  ALA B O   1 
ATOM   6453 C CB  . ALA B 1 493 ? 131.586 103.587 137.397 1.00 201.74 ?  493  ALA B CB  1 
ATOM   6454 N N   . PHE B 1 494 ? 133.913 105.377 136.506 1.00 215.80 ?  494  PHE B N   1 
ATOM   6455 C CA  . PHE B 1 494 ? 135.328 105.593 136.281 1.00 215.80 ?  494  PHE B CA  1 
ATOM   6456 C C   . PHE B 1 494 ? 135.809 106.825 137.020 1.00 215.80 ?  494  PHE B C   1 
ATOM   6457 O O   . PHE B 1 494 ? 136.827 106.782 137.697 1.00 215.80 ?  494  PHE B O   1 
ATOM   6458 C CB  . PHE B 1 494 ? 135.626 105.725 134.793 1.00 215.80 ?  494  PHE B CB  1 
ATOM   6459 C CG  . PHE B 1 494 ? 137.083 105.855 134.492 1.00 215.80 ?  494  PHE B CG  1 
ATOM   6460 C CD1 . PHE B 1 494 ? 137.925 104.772 134.649 1.00 215.80 ?  494  PHE B CD1 1 
ATOM   6461 C CD2 . PHE B 1 494 ? 137.618 107.064 134.084 1.00 215.80 ?  494  PHE B CD2 1 
ATOM   6462 C CE1 . PHE B 1 494 ? 139.272 104.885 134.392 1.00 215.80 ?  494  PHE B CE1 1 
ATOM   6463 C CE2 . PHE B 1 494 ? 138.963 107.186 133.825 1.00 215.80 ?  494  PHE B CE2 1 
ATOM   6464 C CZ  . PHE B 1 494 ? 139.791 106.095 133.981 1.00 215.80 ?  494  PHE B CZ  1 
ATOM   6465 N N   . GLY B 1 495 ? 135.077 107.922 136.899 1.00 214.99 ?  495  GLY B N   1 
ATOM   6466 C CA  . GLY B 1 495 ? 135.458 109.144 137.564 1.00 214.99 ?  495  GLY B CA  1 
ATOM   6467 C C   . GLY B 1 495 ? 135.469 109.001 139.058 1.00 214.99 ?  495  GLY B C   1 
ATOM   6468 O O   . GLY B 1 495 ? 136.364 109.498 139.713 1.00 214.99 ?  495  GLY B O   1 
ATOM   6469 N N   . ARG B 1 496 ? 134.481 108.314 139.607 1.00 225.16 ?  496  ARG B N   1 
ATOM   6470 C CA  . ARG B 1 496 ? 134.436 108.091 141.037 1.00 225.16 ?  496  ARG B CA  1 
ATOM   6471 C C   . ARG B 1 496 ? 135.627 107.285 141.474 1.00 225.16 ?  496  ARG B C   1 
ATOM   6472 O O   . ARG B 1 496 ? 136.264 107.628 142.445 1.00 225.16 ?  496  ARG B O   1 
ATOM   6473 C CB  . ARG B 1 496 ? 133.162 107.371 141.436 1.00 225.16 ?  496  ARG B CB  1 
ATOM   6474 C CG  . ARG B 1 496 ? 132.928 107.325 142.926 1.00 225.16 ?  496  ARG B CG  1 
ATOM   6475 C CD  . ARG B 1 496 ? 132.246 108.586 143.400 1.00 225.16 ?  496  ARG B CD  1 
ATOM   6476 N NE  . ARG B 1 496 ? 132.309 108.703 144.845 1.00 225.16 ?  496  ARG B NE  1 
ATOM   6477 C CZ  . ARG B 1 496 ? 131.444 109.389 145.576 1.00 225.16 ?  496  ARG B CZ  1 
ATOM   6478 N NH1 . ARG B 1 496 ? 130.437 110.018 145.001 1.00 225.16 ?  496  ARG B NH1 1 
ATOM   6479 N NH2 . ARG B 1 496 ? 131.584 109.434 146.886 1.00 225.16 ?  496  ARG B NH2 1 
ATOM   6480 N N   . LEU B 1 497 ? 135.945 106.222 140.754 1.00 207.47 ?  497  LEU B N   1 
ATOM   6481 C CA  . LEU B 1 497 ? 137.117 105.421 141.072 1.00 207.47 ?  497  LEU B CA  1 
ATOM   6482 C C   . LEU B 1 497 ? 138.350 106.299 141.133 1.00 207.47 ?  497  LEU B C   1 
ATOM   6483 O O   . LEU B 1 497 ? 139.096 106.236 142.097 1.00 207.47 ?  497  LEU B O   1 
ATOM   6484 C CB  . LEU B 1 497 ? 137.281 104.300 140.047 1.00 207.47 ?  497  LEU B CB  1 
ATOM   6485 C CG  . LEU B 1 497 ? 138.607 103.573 139.871 1.00 207.47 ?  497  LEU B CG  1 
ATOM   6486 C CD1 . LEU B 1 497 ? 138.482 102.168 140.423 1.00 207.47 ?  497  LEU B CD1 1 
ATOM   6487 C CD2 . LEU B 1 497 ? 138.975 103.538 138.397 1.00 207.47 ?  497  LEU B CD2 1 
ATOM   6488 N N   . VAL B 1 498 ? 138.553 107.142 140.130 1.00 210.38 ?  498  VAL B N   1 
ATOM   6489 C CA  . VAL B 1 498 ? 139.685 108.055 140.136 1.00 210.38 ?  498  VAL B CA  1 
ATOM   6490 C C   . VAL B 1 498 ? 139.634 108.964 141.352 1.00 210.38 ?  498  VAL B C   1 
ATOM   6491 O O   . VAL B 1 498 ? 140.611 109.074 142.068 1.00 210.38 ?  498  VAL B O   1 
ATOM   6492 C CB  . VAL B 1 498 ? 139.769 108.870 138.829 1.00 210.38 ?  498  VAL B CB  1 
ATOM   6493 C CG1 . VAL B 1 498 ? 140.882 109.906 138.898 1.00 210.38 ?  498  VAL B CG1 1 
ATOM   6494 C CG2 . VAL B 1 498 ? 139.996 107.941 137.650 1.00 210.38 ?  498  VAL B CG2 1 
ATOM   6495 N N   . GLY B 1 499 ? 138.493 109.585 141.614 1.00 215.52 ?  499  GLY B N   1 
ATOM   6496 C CA  . GLY B 1 499 ? 138.347 110.442 142.776 1.00 215.52 ?  499  GLY B CA  1 
ATOM   6497 C C   . GLY B 1 499 ? 138.513 109.786 144.129 1.00 215.52 ?  499  GLY B C   1 
ATOM   6498 O O   . GLY B 1 499 ? 138.994 110.417 145.055 1.00 215.52 ?  499  GLY B O   1 
ATOM   6499 N N   . GLU B 1 500 ? 138.115 108.528 144.262 1.00 232.84 ?  500  GLU B N   1 
ATOM   6500 C CA  . GLU B 1 500 ? 138.287 107.809 145.515 1.00 232.84 ?  500  GLU B CA  1 
ATOM   6501 C C   . GLU B 1 500 ? 139.730 107.407 145.682 1.00 232.84 ?  500  GLU B C   1 
ATOM   6502 O O   . GLU B 1 500 ? 140.228 107.341 146.798 1.00 232.84 ?  500  GLU B O   1 
ATOM   6503 C CB  . GLU B 1 500 ? 137.382 106.577 145.588 1.00 232.84 ?  500  GLU B CB  1 
ATOM   6504 C CG  . GLU B 1 500 ? 135.889 106.859 145.563 1.00 232.84 ?  500  GLU B CG  1 
ATOM   6505 C CD  . GLU B 1 500 ? 135.343 107.384 146.872 1.00 232.84 ?  500  GLU B CD  1 
ATOM   6506 O OE1 . GLU B 1 500 ? 136.047 107.331 147.894 1.00 232.84 ?  500  GLU B OE1 1 
ATOM   6507 O OE2 . GLU B 1 500 ? 134.192 107.856 146.880 1.00 232.84 ?  500  GLU B OE2 1 
ATOM   6508 N N   . ILE B 1 501 ? 140.414 107.135 144.582 1.00 224.81 ?  501  ILE B N   1 
ATOM   6509 C CA  . ILE B 1 501 ? 141.832 106.831 144.657 1.00 224.81 ?  501  ILE B CA  1 
ATOM   6510 C C   . ILE B 1 501 ? 142.539 108.124 145.010 1.00 224.81 ?  501  ILE B C   1 
ATOM   6511 O O   . ILE B 1 501 ? 143.435 108.130 145.836 1.00 224.81 ?  501  ILE B O   1 
ATOM   6512 C CB  . ILE B 1 501 ? 142.350 106.229 143.334 1.00 224.81 ?  501  ILE B CB  1 
ATOM   6513 C CG1 . ILE B 1 501 ? 141.921 104.769 143.220 1.00 224.81 ?  501  ILE B CG1 1 
ATOM   6514 C CG2 . ILE B 1 501 ? 143.864 106.321 143.217 1.00 224.81 ?  501  ILE B CG2 1 
ATOM   6515 C CD1 . ILE B 1 501 ? 142.052 104.212 141.821 1.00 224.81 ?  501  ILE B CD1 1 
ATOM   6516 N N   . MET B 1 502 ? 142.098 109.238 144.437 1.00 231.93 ?  502  MET B N   1 
ATOM   6517 C CA  . MET B 1 502 ? 142.685 110.531 144.750 1.00 231.93 ?  502  MET B CA  1 
ATOM   6518 C C   . MET B 1 502 ? 142.469 110.886 146.206 1.00 231.93 ?  502  MET B C   1 
ATOM   6519 O O   . MET B 1 502 ? 143.281 111.573 146.797 1.00 231.93 ?  502  MET B O   1 
ATOM   6520 C CB  . MET B 1 502 ? 142.095 111.618 143.858 1.00 231.93 ?  502  MET B CB  1 
ATOM   6521 C CG  . MET B 1 502 ? 142.698 111.694 142.469 1.00 231.93 ?  502  MET B CG  1 
ATOM   6522 S SD  . MET B 1 502 ? 144.393 112.296 142.473 1.00 231.93 ?  502  MET B SD  1 
ATOM   6523 C CE  . MET B 1 502 ? 144.140 114.062 142.617 1.00 231.93 ?  502  MET B CE  1 
ATOM   6524 N N   . ALA B 1 503 ? 141.379 110.410 146.791 1.00 224.20 ?  503  ALA B N   1 
ATOM   6525 C CA  . ALA B 1 503 ? 141.100 110.672 148.191 1.00 224.20 ?  503  ALA B CA  1 
ATOM   6526 C C   . ALA B 1 503 ? 141.954 109.801 149.079 1.00 224.20 ?  503  ALA B C   1 
ATOM   6527 O O   . ALA B 1 503 ? 142.239 110.164 150.207 1.00 224.20 ?  503  ALA B O   1 
ATOM   6528 C CB  . ALA B 1 503 ? 139.636 110.442 148.478 1.00 224.20 ?  503  ALA B CB  1 
ATOM   6529 N N   . MET B 1 504 ? 142.359 108.642 148.587 1.00 242.39 ?  504  MET B N   1 
ATOM   6530 C CA  . MET B 1 504 ? 143.252 107.788 149.352 1.00 242.39 ?  504  MET B CA  1 
ATOM   6531 C C   . MET B 1 504 ? 144.640 108.382 149.294 1.00 242.39 ?  504  MET B C   1 
ATOM   6532 O O   . MET B 1 504 ? 145.350 108.401 150.293 1.00 242.39 ?  504  MET B O   1 
ATOM   6533 C CB  . MET B 1 504 ? 143.297 106.396 148.743 1.00 242.39 ?  504  MET B CB  1 
ATOM   6534 C CG  . MET B 1 504 ? 142.163 105.484 149.146 1.00 242.39 ?  504  MET B CG  1 
ATOM   6535 S SD  . MET B 1 504 ? 142.026 104.094 148.012 1.00 242.39 ?  504  MET B SD  1 
ATOM   6536 C CE  . MET B 1 504 ? 143.559 104.262 147.104 1.00 242.39 ?  504  MET B CE  1 
ATOM   6537 N N   . LEU B 1 505 ? 145.033 108.867 148.123 1.00 248.74 ?  505  LEU B N   1 
ATOM   6538 C CA  . LEU B 1 505 ? 146.352 109.465 147.955 1.00 248.74 ?  505  LEU B CA  1 
ATOM   6539 C C   . LEU B 1 505 ? 146.447 110.754 148.734 1.00 248.74 ?  505  LEU B C   1 
ATOM   6540 O O   . LEU B 1 505 ? 147.518 111.112 149.212 1.00 248.74 ?  505  LEU B O   1 
ATOM   6541 C CB  . LEU B 1 505 ? 146.622 109.751 146.483 1.00 248.74 ?  505  LEU B CB  1 
ATOM   6542 C CG  . LEU B 1 505 ? 146.683 108.571 145.521 1.00 248.74 ?  505  LEU B CG  1 
ATOM   6543 C CD1 . LEU B 1 505 ? 146.757 109.078 144.090 1.00 248.74 ?  505  LEU B CD1 1 
ATOM   6544 C CD2 . LEU B 1 505 ? 147.856 107.664 145.847 1.00 248.74 ?  505  LEU B CD2 1 
ATOM   6545 N N   . PHE B 1 506 ? 145.335 111.462 148.852 1.00 246.98 ?  506  PHE B N   1 
ATOM   6546 C CA  . PHE B 1 506 ? 145.318 112.725 149.576 1.00 246.98 ?  506  PHE B CA  1 
ATOM   6547 C C   . PHE B 1 506 ? 144.215 112.720 150.610 1.00 246.98 ?  506  PHE B C   1 
ATOM   6548 O O   . PHE B 1 506 ? 143.161 113.310 150.389 1.00 246.98 ?  506  PHE B O   1 
ATOM   6549 C CB  . PHE B 1 506 ? 145.095 113.883 148.612 1.00 246.98 ?  506  PHE B CB  1 
ATOM   6550 C CG  . PHE B 1 506 ? 146.137 113.984 147.544 1.00 246.98 ?  506  PHE B CG  1 
ATOM   6551 C CD1 . PHE B 1 506 ? 147.383 114.505 147.831 1.00 246.98 ?  506  PHE B CD1 1 
ATOM   6552 C CD2 . PHE B 1 506 ? 145.878 113.544 146.257 1.00 246.98 ?  506  PHE B CD2 1 
ATOM   6553 C CE1 . PHE B 1 506 ? 148.353 114.592 146.854 1.00 246.98 ?  506  PHE B CE1 1 
ATOM   6554 C CE2 . PHE B 1 506 ? 146.844 113.624 145.278 1.00 246.98 ?  506  PHE B CE2 1 
ATOM   6555 C CZ  . PHE B 1 506 ? 148.082 114.153 145.574 1.00 246.98 ?  506  PHE B CZ  1 
ATOM   6556 N N   . PRO B 1 507 ? 144.428 112.033 151.787 1.00 253.49 ?  507  PRO B N   1 
ATOM   6557 C CA  . PRO B 1 507 ? 143.276 112.041 152.699 1.00 253.49 ?  507  PRO B CA  1 
ATOM   6558 C C   . PRO B 1 507 ? 143.151 113.343 153.442 1.00 253.49 ?  507  PRO B C   1 
ATOM   6559 O O   . PRO B 1 507 ? 142.198 113.529 154.194 1.00 253.49 ?  507  PRO B O   1 
ATOM   6560 C CB  . PRO B 1 507 ? 143.599 110.918 153.693 1.00 253.49 ?  507  PRO B CB  1 
ATOM   6561 C CG  . PRO B 1 507 ? 144.790 110.207 153.159 1.00 253.49 ?  507  PRO B CG  1 
ATOM   6562 C CD  . PRO B 1 507 ? 145.531 111.253 152.406 1.00 253.49 ?  507  PRO B CD  1 
ATOM   6563 N N   . ASP B 1 508 ? 144.104 114.241 153.239 1.00 263.43 ?  508  ASP B N   1 
ATOM   6564 C CA  . ASP B 1 508 ? 144.101 115.517 153.931 1.00 263.43 ?  508  ASP B CA  1 
ATOM   6565 C C   . ASP B 1 508 ? 143.686 116.573 152.945 1.00 263.43 ?  508  ASP B C   1 
ATOM   6566 O O   . ASP B 1 508 ? 143.303 117.675 153.326 1.00 263.43 ?  508  ASP B O   1 
ATOM   6567 C CB  . ASP B 1 508 ? 145.507 115.803 154.426 1.00 263.43 ?  508  ASP B CB  1 
ATOM   6568 C CG  . ASP B 1 508 ? 146.542 114.907 153.771 1.00 263.43 ?  508  ASP B CG  1 
ATOM   6569 O OD1 . ASP B 1 508 ? 146.830 115.097 152.569 1.00 263.43 ?  508  ASP B OD1 1 
ATOM   6570 O OD2 . ASP B 1 508 ? 147.061 114.002 154.457 1.00 263.43 ?  508  ASP B OD2 1 
ATOM   6571 N N   . GLY B 1 509 ? 143.757 116.238 151.666 1.00 262.92 ?  509  GLY B N   1 
ATOM   6572 C CA  . GLY B 1 509 ? 143.427 117.201 150.640 1.00 262.92 ?  509  GLY B CA  1 
ATOM   6573 C C   . GLY B 1 509 ? 144.712 117.726 150.058 1.00 262.92 ?  509  GLY B C   1 
ATOM   6574 O O   . GLY B 1 509 ? 145.786 117.482 150.598 1.00 262.92 ?  509  GLY B O   1 
ATOM   6575 N N   . ILE B 1 510 ? 144.613 118.439 148.941 1.00 274.31 ?  510  ILE B N   1 
ATOM   6576 C CA  . ILE B 1 510 ? 145.795 119.020 148.315 1.00 274.31 ?  510  ILE B CA  1 
ATOM   6577 C C   . ILE B 1 510 ? 145.841 120.518 148.519 1.00 274.31 ?  510  ILE B C   1 
ATOM   6578 O O   . ILE B 1 510 ? 144.866 121.209 148.259 1.00 274.31 ?  510  ILE B O   1 
ATOM   6579 C CB  . ILE B 1 510 ? 145.835 118.772 146.801 1.00 274.31 ?  510  ILE B CB  1 
ATOM   6580 C CG1 . ILE B 1 510 ? 144.857 117.685 146.385 1.00 274.31 ?  510  ILE B CG1 1 
ATOM   6581 C CG2 . ILE B 1 510 ? 147.234 118.381 146.365 1.00 274.31 ?  510  ILE B CG2 1 
ATOM   6582 C CD1 . ILE B 1 510 ? 145.245 117.055 145.071 1.00 274.31 ?  510  ILE B CD1 1 
ATOM   6583 N N   . LEU B 1 511 ? 146.974 121.027 148.979 1.00 278.35 ?  511  LEU B N   1 
ATOM   6584 C CA  . LEU B 1 511 ? 147.116 122.465 149.122 1.00 278.35 ?  511  LEU B CA  1 
ATOM   6585 C C   . LEU B 1 511 ? 147.709 123.039 147.851 1.00 278.35 ?  511  LEU B C   1 
ATOM   6586 O O   . LEU B 1 511 ? 148.797 122.645 147.441 1.00 278.35 ?  511  LEU B O   1 
ATOM   6587 C CB  . LEU B 1 511 ? 148.006 122.807 150.313 1.00 278.35 ?  511  LEU B CB  1 
ATOM   6588 C CG  . LEU B 1 511 ? 147.955 124.259 150.785 1.00 278.35 ?  511  LEU B CG  1 
ATOM   6589 C CD1 . LEU B 1 511 ? 147.550 124.319 152.246 1.00 278.35 ?  511  LEU B CD1 1 
ATOM   6590 C CD2 . LEU B 1 511 ? 149.297 124.941 150.578 1.00 278.35 ?  511  LEU B CD2 1 
ATOM   6591 N N   . PHE B 1 512 ? 147.004 123.966 147.218 1.00 288.57 ?  512  PHE B N   1 
ATOM   6592 C CA  . PHE B 1 512 ? 147.566 124.604 146.041 1.00 288.57 ?  512  PHE B CA  1 
ATOM   6593 C C   . PHE B 1 512 ? 148.098 125.974 146.395 1.00 288.57 ?  512  PHE B C   1 
ATOM   6594 O O   . PHE B 1 512 ? 149.306 126.200 146.380 1.00 288.57 ?  512  PHE B O   1 
ATOM   6595 C CB  . PHE B 1 512 ? 146.545 124.726 144.913 1.00 288.57 ?  512  PHE B CB  1 
ATOM   6596 C CG  . PHE B 1 512 ? 147.157 125.103 143.604 1.00 288.57 ?  512  PHE B CG  1 
ATOM   6597 C CD1 . PHE B 1 512 ? 148.102 124.286 143.014 1.00 288.57 ?  512  PHE B CD1 1 
ATOM   6598 C CD2 . PHE B 1 512 ? 146.814 126.286 142.979 1.00 288.57 ?  512  PHE B CD2 1 
ATOM   6599 C CE1 . PHE B 1 512 ? 148.685 124.633 141.814 1.00 288.57 ?  512  PHE B CE1 1 
ATOM   6600 C CE2 . PHE B 1 512 ? 147.394 126.645 141.782 1.00 288.57 ?  512  PHE B CE2 1 
ATOM   6601 C CZ  . PHE B 1 512 ? 148.334 125.817 141.198 1.00 288.57 ?  512  PHE B CZ  1 
ATOM   6602 N N   . ASP B 1 513 ? 147.197 126.895 146.699 1.00 309.02 ?  513  ASP B N   1 
ATOM   6603 C CA  . ASP B 1 513 ? 147.609 128.241 147.047 1.00 309.02 ?  513  ASP B CA  1 
ATOM   6604 C C   . ASP B 1 513 ? 147.934 128.253 148.516 1.00 309.02 ?  513  ASP B C   1 
ATOM   6605 O O   . ASP B 1 513 ? 149.089 128.097 148.907 1.00 309.02 ?  513  ASP B O   1 
ATOM   6606 C CB  . ASP B 1 513 ? 146.475 129.222 146.763 1.00 309.02 ?  513  ASP B CB  1 
ATOM   6607 C CG  . ASP B 1 513 ? 145.583 128.770 145.620 1.00 309.02 ?  513  ASP B CG  1 
ATOM   6608 O OD1 . ASP B 1 513 ? 144.640 127.985 145.859 1.00 309.02 ?  513  ASP B OD1 1 
ATOM   6609 O OD2 . ASP B 1 513 ? 145.826 129.205 144.477 1.00 309.02 ?  513  ASP B OD2 1 
ATOM   6610 N N   . ASP B 1 514 ? 146.918 128.449 149.339 1.00 319.74 ?  514  ASP B N   1 
ATOM   6611 C CA  . ASP B 1 514 ? 147.108 128.420 150.776 1.00 319.74 ?  514  ASP B CA  1 
ATOM   6612 C C   . ASP B 1 514 ? 145.895 127.676 151.254 1.00 319.74 ?  514  ASP B C   1 
ATOM   6613 O O   . ASP B 1 514 ? 145.708 127.464 152.450 1.00 319.74 ?  514  ASP B O   1 
ATOM   6614 C CB  . ASP B 1 514 ? 147.118 129.834 151.344 1.00 319.74 ?  514  ASP B CB  1 
ATOM   6615 C CG  . ASP B 1 514 ? 146.285 130.797 150.521 1.00 319.74 ?  514  ASP B CG  1 
ATOM   6616 O OD1 . ASP B 1 514 ? 145.051 130.841 150.714 1.00 319.74 ?  514  ASP B OD1 1 
ATOM   6617 O OD2 . ASP B 1 514 ? 146.864 131.513 149.679 1.00 319.74 ?  514  ASP B OD2 1 
ATOM   6618 N N   . ILE B 1 515 ? 145.056 127.280 150.306 1.00 292.48 ?  515  ILE B N   1 
ATOM   6619 C CA  . ILE B 1 515 ? 143.839 126.573 150.652 1.00 292.48 ?  515  ILE B CA  1 
ATOM   6620 C C   . ILE B 1 515 ? 143.998 125.091 150.437 1.00 292.48 ?  515  ILE B C   1 
ATOM   6621 O O   . ILE B 1 515 ? 144.536 124.668 149.421 1.00 292.48 ?  515  ILE B O   1 
ATOM   6622 C CB  . ILE B 1 515 ? 142.667 127.058 149.789 1.00 292.48 ?  515  ILE B CB  1 
ATOM   6623 C CG1 . ILE B 1 515 ? 143.094 128.255 148.941 1.00 292.48 ?  515  ILE B CG1 1 
ATOM   6624 C CG2 . ILE B 1 515 ? 141.475 127.410 150.663 1.00 292.48 ?  515  ILE B CG2 1 
ATOM   6625 C CD1 . ILE B 1 515 ? 142.026 129.312 148.780 1.00 292.48 ?  515  ILE B CD1 1 
ATOM   6626 N N   . ILE B 1 516 ? 143.552 124.295 151.399 1.00 282.09 ?  516  ILE B N   1 
ATOM   6627 C CA  . ILE B 1 516 ? 143.587 122.854 151.224 1.00 282.09 ?  516  ILE B CA  1 
ATOM   6628 C C   . ILE B 1 516 ? 142.280 122.463 150.586 1.00 282.09 ?  516  ILE B C   1 
ATOM   6629 O O   . ILE B 1 516 ? 141.218 122.906 151.014 1.00 282.09 ?  516  ILE B O   1 
ATOM   6630 C CB  . ILE B 1 516 ? 143.727 122.104 152.552 1.00 282.09 ?  516  ILE B CB  1 
ATOM   6631 C CG1 . ILE B 1 516 ? 144.098 123.073 153.673 1.00 282.09 ?  516  ILE B CG1 1 
ATOM   6632 C CG2 . ILE B 1 516 ? 144.763 120.998 152.424 1.00 282.09 ?  516  ILE B CG2 1 
ATOM   6633 C CD1 . ILE B 1 516 ? 144.936 122.444 154.763 1.00 282.09 ?  516  ILE B CD1 1 
ATOM   6634 N N   . TYR B 1 517 ? 142.347 121.641 149.553 1.00 286.12 ?  517  TYR B N   1 
ATOM   6635 C CA  . TYR B 1 517 ? 141.143 121.262 148.847 1.00 286.12 ?  517  TYR B CA  1 
ATOM   6636 C C   . TYR B 1 517 ? 140.880 119.793 149.023 1.00 286.12 ?  517  TYR B C   1 
ATOM   6637 O O   . TYR B 1 517 ? 141.515 118.967 148.372 1.00 286.12 ?  517  TYR B O   1 
ATOM   6638 C CB  . TYR B 1 517 ? 141.280 121.561 147.365 1.00 286.12 ?  517  TYR B CB  1 
ATOM   6639 C CG  . TYR B 1 517 ? 141.260 123.025 146.990 1.00 286.12 ?  517  TYR B CG  1 
ATOM   6640 C CD1 . TYR B 1 517 ? 142.396 123.806 147.110 1.00 286.12 ?  517  TYR B CD1 1 
ATOM   6641 C CD2 . TYR B 1 517 ? 140.118 123.614 146.474 1.00 286.12 ?  517  TYR B CD2 1 
ATOM   6642 C CE1 . TYR B 1 517 ? 142.401 125.127 146.737 1.00 286.12 ?  517  TYR B CE1 1 
ATOM   6643 C CE2 . TYR B 1 517 ? 140.111 124.945 146.110 1.00 286.12 ?  517  TYR B CE2 1 
ATOM   6644 C CZ  . TYR B 1 517 ? 141.258 125.692 146.250 1.00 286.12 ?  517  TYR B CZ  1 
ATOM   6645 O OH  . TYR B 1 517 ? 141.277 127.011 145.896 1.00 286.12 ?  517  TYR B OH  1 
ATOM   6646 N N   . LYS B 1 518 ? 139.939 119.457 149.896 1.00 248.57 ?  518  LYS B N   1 
ATOM   6647 C CA  . LYS B 1 518 ? 139.576 118.065 150.092 1.00 248.57 ?  518  LYS B CA  1 
ATOM   6648 C C   . LYS B 1 518 ? 138.998 117.519 148.801 1.00 248.57 ?  518  LYS B C   1 
ATOM   6649 O O   . LYS B 1 518 ? 138.175 118.173 148.163 1.00 248.57 ?  518  LYS B O   1 
ATOM   6650 C CB  . LYS B 1 518 ? 138.572 117.930 151.231 1.00 248.57 ?  518  LYS B CB  1 
ATOM   6651 C CG  . LYS B 1 518 ? 138.503 116.545 151.858 1.00 248.57 ?  518  LYS B CG  1 
ATOM   6652 C CD  . LYS B 1 518 ? 139.871 115.892 151.980 1.00 248.57 ?  518  LYS B CD  1 
ATOM   6653 C CE  . LYS B 1 518 ? 139.762 114.381 151.850 1.00 248.57 ?  518  LYS B CE  1 
ATOM   6654 N NZ  . LYS B 1 518 ? 140.341 113.879 150.576 1.00 248.57 ?  518  LYS B NZ  1 
ATOM   6655 N N   . ILE B 1 519 ? 139.423 116.323 148.411 1.00 216.28 ?  519  ILE B N   1 
ATOM   6656 C CA  . ILE B 1 519 ? 138.966 115.742 147.161 1.00 216.28 ?  519  ILE B CA  1 
ATOM   6657 C C   . ILE B 1 519 ? 137.473 115.462 147.153 1.00 216.28 ?  519  ILE B C   1 
ATOM   6658 O O   . ILE B 1 519 ? 136.958 114.881 148.101 1.00 216.28 ?  519  ILE B O   1 
ATOM   6659 C CB  . ILE B 1 519 ? 139.715 114.420 146.915 1.00 216.28 ?  519  ILE B CB  1 
ATOM   6660 C CG1 . ILE B 1 519 ? 141.218 114.625 147.114 1.00 216.28 ?  519  ILE B CG1 1 
ATOM   6661 C CG2 . ILE B 1 519 ? 139.425 113.863 145.536 1.00 216.28 ?  519  ILE B CG2 1 
ATOM   6662 C CD1 . ILE B 1 519 ? 141.932 115.095 145.872 1.00 216.28 ?  519  ILE B CD1 1 
ATOM   6663 N N   . LEU B 1 520 ? 136.769 115.904 146.112 1.00 225.65 ?  520  LEU B N   1 
ATOM   6664 C CA  . LEU B 1 520 ? 135.352 115.585 145.976 1.00 225.65 ?  520  LEU B CA  1 
ATOM   6665 C C   . LEU B 1 520 ? 135.254 114.412 144.965 1.00 225.65 ?  520  LEU B C   1 
ATOM   6666 O O   . LEU B 1 520 ? 135.233 114.676 143.771 1.00 225.65 ?  520  LEU B O   1 
ATOM   6667 C CB  . LEU B 1 520 ? 134.542 116.781 145.488 1.00 225.65 ?  520  LEU B CB  1 
ATOM   6668 C CG  . LEU B 1 520 ? 133.118 116.979 146.019 1.00 225.65 ?  520  LEU B CG  1 
ATOM   6669 C CD1 . LEU B 1 520 ? 132.511 115.701 146.570 1.00 225.65 ?  520  LEU B CD1 1 
ATOM   6670 C CD2 . LEU B 1 520 ? 133.065 118.075 147.069 1.00 225.65 ?  520  LEU B CD2 1 
ATOM   6671 N N   . PRO B 1 521 ? 135.183 113.117 145.425 1.00 240.84 ?  521  PRO B N   1 
ATOM   6672 C CA  . PRO B 1 521 ? 135.153 112.066 144.404 1.00 240.84 ?  521  PRO B CA  1 
ATOM   6673 C C   . PRO B 1 521 ? 133.922 112.116 143.511 1.00 240.84 ?  521  PRO B C   1 
ATOM   6674 O O   . PRO B 1 521 ? 133.980 111.631 142.388 1.00 240.84 ?  521  PRO B O   1 
ATOM   6675 C CB  . PRO B 1 521 ? 135.152 110.789 145.237 1.00 240.84 ?  521  PRO B CB  1 
ATOM   6676 C CG  . PRO B 1 521 ? 135.654 111.184 146.580 1.00 240.84 ?  521  PRO B CG  1 
ATOM   6677 C CD  . PRO B 1 521 ? 135.103 112.553 146.779 1.00 240.84 ?  521  PRO B CD  1 
ATOM   6678 N N   . GLY B 1 522 ? 132.826 112.695 143.991 1.00 248.08 ?  522  GLY B N   1 
ATOM   6679 C CA  . GLY B 1 522 ? 131.624 112.814 143.197 1.00 248.08 ?  522  GLY B CA  1 
ATOM   6680 C C   . GLY B 1 522 ? 131.778 113.844 142.116 1.00 248.08 ?  522  GLY B C   1 
ATOM   6681 O O   . GLY B 1 522 ? 131.132 113.747 141.088 1.00 248.08 ?  522  GLY B O   1 
ATOM   6682 N N   . GLY B 1 523 ? 132.622 114.840 142.343 1.00 250.29 ?  523  GLY B N   1 
ATOM   6683 C CA  . GLY B 1 523 ? 132.884 115.839 141.328 1.00 250.29 ?  523  GLY B CA  1 
ATOM   6684 C C   . GLY B 1 523 ? 133.624 115.177 140.208 1.00 250.29 ?  523  GLY B C   1 
ATOM   6685 O O   . GLY B 1 523 ? 133.310 115.412 139.056 1.00 250.29 ?  523  GLY B O   1 
ATOM   6686 N N   . TYR B 1 524 ? 134.579 114.319 140.541 1.00 229.92 ?  524  TYR B N   1 
ATOM   6687 C CA  . TYR B 1 524 ? 135.330 113.582 139.537 1.00 229.92 ?  524  TYR B CA  1 
ATOM   6688 C C   . TYR B 1 524 ? 134.399 112.709 138.733 1.00 229.92 ?  524  TYR B C   1 
ATOM   6689 O O   . TYR B 1 524 ? 134.605 112.523 137.541 1.00 229.92 ?  524  TYR B O   1 
ATOM   6690 C CB  . TYR B 1 524 ? 136.363 112.696 140.216 1.00 229.92 ?  524  TYR B CB  1 
ATOM   6691 C CG  . TYR B 1 524 ? 137.622 113.382 140.668 1.00 229.92 ?  524  TYR B CG  1 
ATOM   6692 C CD1 . TYR B 1 524 ? 137.620 114.219 141.768 1.00 229.92 ?  524  TYR B CD1 1 
ATOM   6693 C CD2 . TYR B 1 524 ? 138.822 113.163 140.016 1.00 229.92 ?  524  TYR B CD2 1 
ATOM   6694 C CE1 . TYR B 1 524 ? 138.769 114.844 142.189 1.00 229.92 ?  524  TYR B CE1 1 
ATOM   6695 C CE2 . TYR B 1 524 ? 139.979 113.782 140.432 1.00 229.92 ?  524  TYR B CE2 1 
ATOM   6696 C CZ  . TYR B 1 524 ? 139.943 114.620 141.520 1.00 229.92 ?  524  TYR B CZ  1 
ATOM   6697 O OH  . TYR B 1 524 ? 141.082 115.241 141.945 1.00 229.92 ?  524  TYR B OH  1 
ATOM   6698 N N   . ALA B 1 525 ? 133.376 112.164 139.376 1.00 256.65 ?  525  ALA B N   1 
ATOM   6699 C CA  . ALA B 1 525 ? 132.402 111.339 138.683 1.00 256.65 ?  525  ALA B CA  1 
ATOM   6700 C C   . ALA B 1 525 ? 131.621 112.100 137.630 1.00 256.65 ?  525  ALA B C   1 
ATOM   6701 O O   . ALA B 1 525 ? 131.396 111.581 136.552 1.00 256.65 ?  525  ALA B O   1 
ATOM   6702 C CB  . ALA B 1 525 ? 131.466 110.703 139.680 1.00 256.65 ?  525  ALA B CB  1 
ATOM   6703 N N   . VAL B 1 526 ? 131.208 113.327 137.929 1.00 270.30 ?  526  VAL B N   1 
ATOM   6704 C CA  . VAL B 1 526 ? 130.512 114.148 136.941 1.00 270.30 ?  526  VAL B CA  1 
ATOM   6705 C C   . VAL B 1 526 ? 131.408 114.393 135.735 1.00 270.30 ?  526  VAL B C   1 
ATOM   6706 O O   . VAL B 1 526 ? 130.974 114.272 134.593 1.00 270.30 ?  526  VAL B O   1 
ATOM   6707 C CB  . VAL B 1 526 ? 130.022 115.483 137.544 1.00 270.30 ?  526  VAL B CB  1 
ATOM   6708 C CG1 . VAL B 1 526 ? 129.061 116.188 136.607 1.00 270.30 ?  526  VAL B CG1 1 
ATOM   6709 C CG2 . VAL B 1 526 ? 129.341 115.259 138.878 1.00 270.30 ?  526  VAL B CG2 1 
ATOM   6710 N N   . ILE B 1 527 ? 132.670 114.712 135.980 1.00 254.86 ?  527  ILE B N   1 
ATOM   6711 C CA  . ILE B 1 527 ? 133.611 114.913 134.886 1.00 254.86 ?  527  ILE B CA  1 
ATOM   6712 C C   . ILE B 1 527 ? 133.736 113.657 134.053 1.00 254.86 ?  527  ILE B C   1 
ATOM   6713 O O   . ILE B 1 527 ? 133.641 113.713 132.835 1.00 254.86 ?  527  ILE B O   1 
ATOM   6714 C CB  . ILE B 1 527 ? 134.996 115.298 135.413 1.00 254.86 ?  527  ILE B CB  1 
ATOM   6715 C CG1 . ILE B 1 527 ? 134.862 116.310 136.531 1.00 254.86 ?  527  ILE B CG1 1 
ATOM   6716 C CG2 . ILE B 1 527 ? 135.851 115.894 134.322 1.00 254.86 ?  527  ILE B CG2 1 
ATOM   6717 C CD1 . ILE B 1 527 ? 135.306 117.688 136.148 1.00 254.86 ?  527  ILE B CD1 1 
ATOM   6718 N N   . GLY B 1 528 ? 133.937 112.521 134.703 1.00 250.40 ?  528  GLY B N   1 
ATOM   6719 C CA  . GLY B 1 528 ? 134.059 111.269 133.994 1.00 250.40 ?  528  GLY B CA  1 
ATOM   6720 C C   . GLY B 1 528 ? 132.851 110.910 133.176 1.00 250.40 ?  528  GLY B C   1 
ATOM   6721 O O   . GLY B 1 528 ? 132.995 110.403 132.076 1.00 250.40 ?  528  GLY B O   1 
ATOM   6722 N N   . ALA B 1 529 ? 131.662 111.148 133.709 1.00 232.85 ?  529  ALA B N   1 
ATOM   6723 C CA  . ALA B 1 529 ? 130.437 110.870 132.985 1.00 232.85 ?  529  ALA B CA  1 
ATOM   6724 C C   . ALA B 1 529 ? 130.447 111.624 131.690 1.00 232.85 ?  529  ALA B C   1 
ATOM   6725 O O   . ALA B 1 529 ? 130.317 111.026 130.634 1.00 232.85 ?  529  ALA B O   1 
ATOM   6726 C CB  . ALA B 1 529 ? 129.242 111.265 133.819 1.00 232.85 ?  529  ALA B CB  1 
ATOM   6727 N N   . ALA B 1 530 ? 130.641 112.935 131.760 1.00 253.14 ?  530  ALA B N   1 
ATOM   6728 C CA  . ALA B 1 530 ? 130.690 113.766 130.569 1.00 253.14 ?  530  ALA B CA  1 
ATOM   6729 C C   . ALA B 1 530 ? 131.790 113.370 129.611 1.00 253.14 ?  530  ALA B C   1 
ATOM   6730 O O   . ALA B 1 530 ? 131.611 113.436 128.406 1.00 253.14 ?  530  ALA B O   1 
ATOM   6731 C CB  . ALA B 1 530 ? 130.871 115.210 130.971 1.00 253.14 ?  530  ALA B CB  1 
ATOM   6732 N N   . ALA B 1 531 ? 132.937 112.974 130.137 1.00 261.07 ?  531  ALA B N   1 
ATOM   6733 C CA  . ALA B 1 531 ? 134.056 112.624 129.289 1.00 261.07 ?  531  ALA B CA  1 
ATOM   6734 C C   . ALA B 1 531 ? 133.838 111.313 128.541 1.00 261.07 ?  531  ALA B C   1 
ATOM   6735 O O   . ALA B 1 531 ? 134.118 111.241 127.358 1.00 261.07 ?  531  ALA B O   1 
ATOM   6736 C CB  . ALA B 1 531 ? 135.345 112.602 130.089 1.00 261.07 ?  531  ALA B CB  1 
ATOM   6737 N N   . LEU B 1 532 ? 133.331 110.281 129.204 1.00 256.25 ?  532  LEU B N   1 
ATOM   6738 C CA  . LEU B 1 532 ? 133.172 109.004 128.530 1.00 256.25 ?  532  LEU B CA  1 
ATOM   6739 C C   . LEU B 1 532 ? 132.043 109.090 127.538 1.00 256.25 ?  532  LEU B C   1 
ATOM   6740 O O   . LEU B 1 532 ? 132.137 108.562 126.437 1.00 256.25 ?  532  LEU B O   1 
ATOM   6741 C CB  . LEU B 1 532 ? 132.946 107.842 129.503 1.00 256.25 ?  532  LEU B CB  1 
ATOM   6742 C CG  . LEU B 1 532 ? 133.911 106.657 129.350 1.00 256.25 ?  532  LEU B CG  1 
ATOM   6743 C CD1 . LEU B 1 532 ? 134.165 105.912 130.648 1.00 256.25 ?  532  LEU B CD1 1 
ATOM   6744 C CD2 . LEU B 1 532 ? 133.503 105.679 128.267 1.00 256.25 ?  532  LEU B CD2 1 
ATOM   6745 N N   . THR B 1 533 ? 130.973 109.775 127.916 1.00 240.29 ?  533  THR B N   1 
ATOM   6746 C CA  . THR B 1 533 ? 129.844 109.912 127.019 1.00 240.29 ?  533  THR B CA  1 
ATOM   6747 C C   . THR B 1 533 ? 130.129 110.920 125.909 1.00 240.29 ?  533  THR B C   1 
ATOM   6748 O O   . THR B 1 533 ? 129.455 110.916 124.892 1.00 240.29 ?  533  THR B O   1 
ATOM   6749 C CB  . THR B 1 533 ? 128.513 110.139 127.781 1.00 240.29 ?  533  THR B CB  1 
ATOM   6750 O OG1 . THR B 1 533 ? 127.414 109.719 126.964 1.00 240.29 ?  533  THR B OG1 1 
ATOM   6751 C CG2 . THR B 1 533 ? 128.332 111.570 128.171 1.00 240.29 ?  533  THR B CG2 1 
ATOM   6752 N N   . GLY B 1 534 ? 131.153 111.750 126.075 1.00 242.01 ?  534  GLY B N   1 
ATOM   6753 C CA  . GLY B 1 534 ? 131.540 112.682 125.032 1.00 242.01 ?  534  GLY B CA  1 
ATOM   6754 C C   . GLY B 1 534 ? 132.535 112.035 124.107 1.00 242.01 ?  534  GLY B C   1 
ATOM   6755 O O   . GLY B 1 534 ? 132.710 112.475 122.987 1.00 242.01 ?  534  GLY B O   1 
ATOM   6756 N N   . ALA B 1 535 ? 133.194 110.986 124.571 1.00 218.20 ?  535  ALA B N   1 
ATOM   6757 C CA  . ALA B 1 535 ? 134.121 110.250 123.736 1.00 218.20 ?  535  ALA B CA  1 
ATOM   6758 C C   . ALA B 1 535 ? 133.380 109.198 122.936 1.00 218.20 ?  535  ALA B C   1 
ATOM   6759 O O   . ALA B 1 535 ? 133.864 108.727 121.918 1.00 218.20 ?  535  ALA B O   1 
ATOM   6760 C CB  . ALA B 1 535 ? 135.143 109.578 124.610 1.00 218.20 ?  535  ALA B CB  1 
ATOM   6761 N N   . VAL B 1 536 ? 132.206 108.806 123.405 1.00 228.69 ?  536  VAL B N   1 
ATOM   6762 C CA  . VAL B 1 536 ? 131.423 107.809 122.702 1.00 228.69 ?  536  VAL B CA  1 
ATOM   6763 C C   . VAL B 1 536 ? 130.612 108.509 121.627 1.00 228.69 ?  536  VAL B C   1 
ATOM   6764 O O   . VAL B 1 536 ? 130.502 108.019 120.515 1.00 228.69 ?  536  VAL B O   1 
ATOM   6765 C CB  . VAL B 1 536 ? 130.563 106.986 123.696 1.00 228.69 ?  536  VAL B CB  1 
ATOM   6766 C CG1 . VAL B 1 536 ? 129.136 106.772 123.219 1.00 228.69 ?  536  VAL B CG1 1 
ATOM   6767 C CG2 . VAL B 1 536 ? 131.228 105.659 124.001 1.00 228.69 ?  536  VAL B CG2 1 
ATOM   6768 N N   . SER B 1 537 ? 130.104 109.695 121.931 1.00 244.47 ?  537  SER B N   1 
ATOM   6769 C CA  . SER B 1 537 ? 129.269 110.410 120.988 1.00 244.47 ?  537  SER B CA  1 
ATOM   6770 C C   . SER B 1 537 ? 130.052 111.399 120.169 1.00 244.47 ?  537  SER B C   1 
ATOM   6771 O O   . SER B 1 537 ? 129.482 112.009 119.266 1.00 244.47 ?  537  SER B O   1 
ATOM   6772 C CB  . SER B 1 537 ? 128.198 111.169 121.750 1.00 244.47 ?  537  SER B CB  1 
ATOM   6773 O OG  . SER B 1 537 ? 128.777 112.177 122.546 1.00 244.47 ?  537  SER B OG  1 
ATOM   6774 N N   . HIS B 1 538 ? 131.336 111.571 120.474 1.00 246.50 ?  538  HIS B N   1 
ATOM   6775 C CA  . HIS B 1 538 ? 132.187 112.546 119.782 1.00 246.50 ?  538  HIS B CA  1 
ATOM   6776 C C   . HIS B 1 538 ? 131.638 113.954 119.881 1.00 246.50 ?  538  HIS B C   1 
ATOM   6777 O O   . HIS B 1 538 ? 131.609 114.680 118.894 1.00 246.50 ?  538  HIS B O   1 
ATOM   6778 C CB  . HIS B 1 538 ? 132.476 112.147 118.337 1.00 246.50 ?  538  HIS B CB  1 
ATOM   6779 C CG  . HIS B 1 538 ? 133.499 111.069 118.206 1.00 246.50 ?  538  HIS B CG  1 
ATOM   6780 N ND1 . HIS B 1 538 ? 133.976 110.646 116.986 1.00 246.50 ?  538  HIS B ND1 1 
ATOM   6781 C CD2 . HIS B 1 538 ? 134.138 110.327 119.140 1.00 246.50 ?  538  HIS B CD2 1 
ATOM   6782 C CE1 . HIS B 1 538 ? 134.867 109.691 117.175 1.00 246.50 ?  538  HIS B CE1 1 
ATOM   6783 N NE2 . HIS B 1 538 ? 134.979 109.474 118.472 1.00 246.50 ?  538  HIS B NE2 1 
ATOM   6784 N N   . THR B 1 539 ? 131.205 114.346 121.076 1.00 247.03 ?  539  THR B N   1 
ATOM   6785 C CA  . THR B 1 539 ? 130.672 115.683 121.290 1.00 247.03 ?  539  THR B CA  1 
ATOM   6786 C C   . THR B 1 539 ? 131.242 116.295 122.543 1.00 247.03 ?  539  THR B C   1 
ATOM   6787 O O   . THR B 1 539 ? 131.668 115.592 123.443 1.00 247.03 ?  539  THR B O   1 
ATOM   6788 C CB  . THR B 1 539 ? 129.154 115.677 121.506 1.00 247.03 ?  539  THR B CB  1 
ATOM   6789 O OG1 . THR B 1 539 ? 128.843 114.901 122.663 1.00 247.03 ?  539  THR B OG1 1 
ATOM   6790 C CG2 . THR B 1 539 ? 128.435 115.128 120.319 1.00 247.03 ?  539  THR B CG2 1 
ATOM   6791 N N   . VAL B 1 540 ? 131.230 117.616 122.618 1.00 231.76 ?  540  VAL B N   1 
ATOM   6792 C CA  . VAL B 1 540 ? 131.711 118.295 123.807 1.00 231.76 ?  540  VAL B CA  1 
ATOM   6793 C C   . VAL B 1 540 ? 130.541 118.906 124.552 1.00 231.76 ?  540  VAL B C   1 
ATOM   6794 O O   . VAL B 1 540 ? 130.725 119.567 125.567 1.00 231.76 ?  540  VAL B O   1 
ATOM   6795 C CB  . VAL B 1 540 ? 132.732 119.387 123.452 1.00 231.76 ?  540  VAL B CB  1 
ATOM   6796 C CG1 . VAL B 1 540 ? 134.133 118.798 123.372 1.00 231.76 ?  540  VAL B CG1 1 
ATOM   6797 C CG2 . VAL B 1 540 ? 132.357 120.058 122.142 1.00 231.76 ?  540  VAL B CG2 1 
ATOM   6798 N N   . SER B 1 541 ? 129.329 118.668 124.065 1.00 248.46 ?  541  SER B N   1 
ATOM   6799 C CA  . SER B 1 541 ? 128.138 119.241 124.679 1.00 248.46 ?  541  SER B CA  1 
ATOM   6800 C C   . SER B 1 541 ? 127.669 118.425 125.846 1.00 248.46 ?  541  SER B C   1 
ATOM   6801 O O   . SER B 1 541 ? 126.737 118.810 126.535 1.00 248.46 ?  541  SER B O   1 
ATOM   6802 C CB  . SER B 1 541 ? 127.026 119.291 123.662 1.00 248.46 ?  541  SER B CB  1 
ATOM   6803 O OG  . SER B 1 541 ? 127.145 118.210 122.763 1.00 248.46 ?  541  SER B OG  1 
ATOM   6804 N N   . THR B 1 542 ? 128.311 117.293 126.078 1.00 250.86 ?  542  THR B N   1 
ATOM   6805 C CA  . THR B 1 542 ? 127.963 116.446 127.197 1.00 250.86 ?  542  THR B CA  1 
ATOM   6806 C C   . THR B 1 542 ? 128.394 117.123 128.468 1.00 250.86 ?  542  THR B C   1 
ATOM   6807 O O   . THR B 1 542 ? 127.851 116.846 129.522 1.00 250.86 ?  542  THR B O   1 
ATOM   6808 C CB  . THR B 1 542 ? 128.668 115.108 127.067 1.00 250.86 ?  542  THR B CB  1 
ATOM   6809 O OG1 . THR B 1 542 ? 130.076 115.329 126.938 1.00 250.86 ?  542  THR B OG1 1 
ATOM   6810 C CG2 . THR B 1 542 ? 128.176 114.406 125.835 1.00 250.86 ?  542  THR B CG2 1 
ATOM   6811 N N   . ALA B 1 543 ? 129.378 118.009 128.377 1.00 235.53 ?  543  ALA B N   1 
ATOM   6812 C CA  . ALA B 1 543 ? 129.803 118.772 129.531 1.00 235.53 ?  543  ALA B CA  1 
ATOM   6813 C C   . ALA B 1 543 ? 128.656 119.652 129.958 1.00 235.53 ?  543  ALA B C   1 
ATOM   6814 O O   . ALA B 1 543 ? 128.338 119.711 131.133 1.00 235.53 ?  543  ALA B O   1 
ATOM   6815 C CB  . ALA B 1 543 ? 131.012 119.611 129.178 1.00 235.53 ?  543  ALA B CB  1 
ATOM   6816 N N   . VAL B 1 544 ? 128.020 120.325 129.004 1.00 243.13 ?  544  VAL B N   1 
ATOM   6817 C CA  . VAL B 1 544 ? 126.873 121.178 129.303 1.00 243.13 ?  544  VAL B CA  1 
ATOM   6818 C C   . VAL B 1 544 ? 125.691 120.368 129.803 1.00 243.13 ?  544  VAL B C   1 
ATOM   6819 O O   . VAL B 1 544 ? 125.001 120.783 130.728 1.00 243.13 ?  544  VAL B O   1 
ATOM   6820 C CB  . VAL B 1 544 ? 126.448 121.992 128.071 1.00 243.13 ?  544  VAL B CB  1 
ATOM   6821 C CG1 . VAL B 1 544 ? 125.806 123.303 128.493 1.00 243.13 ?  544  VAL B CG1 1 
ATOM   6822 C CG2 . VAL B 1 544 ? 127.649 122.257 127.177 1.00 243.13 ?  544  VAL B CG2 1 
ATOM   6823 N N   . ILE B 1 545 ? 125.453 119.209 129.202 1.00 258.02 ?  545  ILE B N   1 
ATOM   6824 C CA  . ILE B 1 545 ? 124.384 118.343 129.669 1.00 258.02 ?  545  ILE B CA  1 
ATOM   6825 C C   . ILE B 1 545 ? 124.642 118.007 131.121 1.00 258.02 ?  545  ILE B C   1 
ATOM   6826 O O   . ILE B 1 545 ? 123.757 118.144 131.954 1.00 258.02 ?  545  ILE B O   1 
ATOM   6827 C CB  . ILE B 1 545 ? 124.268 117.068 128.815 1.00 258.02 ?  545  ILE B CB  1 
ATOM   6828 C CG1 . ILE B 1 545 ? 123.791 117.413 127.410 1.00 258.02 ?  545  ILE B CG1 1 
ATOM   6829 C CG2 . ILE B 1 545 ? 123.304 116.070 129.438 1.00 258.02 ?  545  ILE B CG2 1 
ATOM   6830 C CD1 . ILE B 1 545 ? 123.844 116.256 126.445 1.00 258.02 ?  545  ILE B CD1 1 
ATOM   6831 N N   . CYS B 1 546 ? 125.865 117.608 131.436 1.00 261.36 ?  546  CYS B N   1 
ATOM   6832 C CA  . CYS B 1 546 ? 126.223 117.284 132.807 1.00 261.36 ?  546  CYS B CA  1 
ATOM   6833 C C   . CYS B 1 546 ? 125.991 118.456 133.728 1.00 261.36 ?  546  CYS B C   1 
ATOM   6834 O O   . CYS B 1 546 ? 125.368 118.297 134.750 1.00 261.36 ?  546  CYS B O   1 
ATOM   6835 C CB  . CYS B 1 546 ? 127.679 116.852 132.893 1.00 261.36 ?  546  CYS B CB  1 
ATOM   6836 S SG  . CYS B 1 546 ? 127.911 115.119 133.297 1.00 261.36 ?  546  CYS B SG  1 
ATOM   6837 N N   . PHE B 1 547 ? 126.487 119.632 133.367 1.00 243.82 ?  547  PHE B N   1 
ATOM   6838 C CA  . PHE B 1 547 ? 126.317 120.820 134.193 1.00 243.82 ?  547  PHE B CA  1 
ATOM   6839 C C   . PHE B 1 547 ? 124.874 121.031 134.575 1.00 243.82 ?  547  PHE B C   1 
ATOM   6840 O O   . PHE B 1 547 ? 124.565 121.230 135.739 1.00 243.82 ?  547  PHE B O   1 
ATOM   6841 C CB  . PHE B 1 547 ? 126.782 122.063 133.451 1.00 243.82 ?  547  PHE B CB  1 
ATOM   6842 C CG  . PHE B 1 547 ? 128.264 122.169 133.316 1.00 243.82 ?  547  PHE B CG  1 
ATOM   6843 C CD1 . PHE B 1 547 ? 129.101 121.717 134.317 1.00 243.82 ?  547  PHE B CD1 1 
ATOM   6844 C CD2 . PHE B 1 547 ? 128.820 122.737 132.186 1.00 243.82 ?  547  PHE B CD2 1 
ATOM   6845 C CE1 . PHE B 1 547 ? 130.467 121.826 134.190 1.00 243.82 ?  547  PHE B CE1 1 
ATOM   6846 C CE2 . PHE B 1 547 ? 130.184 122.836 132.046 1.00 243.82 ?  547  PHE B CE2 1 
ATOM   6847 C CZ  . PHE B 1 547 ? 131.007 122.375 133.048 1.00 243.82 ?  547  PHE B CZ  1 
ATOM   6848 N N   . GLU B 1 548 ? 123.985 120.999 133.592 1.00 251.54 ?  548  GLU B N   1 
ATOM   6849 C CA  . GLU B 1 548 ? 122.578 121.231 133.855 1.00 251.54 ?  548  GLU B CA  1 
ATOM   6850 C C   . GLU B 1 548 ? 121.918 120.103 134.625 1.00 251.54 ?  548  GLU B C   1 
ATOM   6851 O O   . GLU B 1 548 ? 121.090 120.362 135.487 1.00 251.54 ?  548  GLU B O   1 
ATOM   6852 C CB  . GLU B 1 548 ? 121.846 121.472 132.545 1.00 251.54 ?  548  GLU B CB  1 
ATOM   6853 C CG  . GLU B 1 548 ? 121.835 122.923 132.108 1.00 251.54 ?  548  GLU B CG  1 
ATOM   6854 C CD  . GLU B 1 548 ? 121.670 123.073 130.613 1.00 251.54 ?  548  GLU B CD  1 
ATOM   6855 O OE1 . GLU B 1 548 ? 122.651 122.836 129.882 1.00 251.54 ?  548  GLU B OE1 1 
ATOM   6856 O OE2 . GLU B 1 548 ? 120.556 123.416 130.170 1.00 251.54 ?  548  GLU B OE2 1 
ATOM   6857 N N   . LEU B 1 549 ? 122.278 118.861 134.330 1.00 243.78 ?  549  LEU B N   1 
ATOM   6858 C CA  . LEU B 1 549 ? 121.729 117.711 135.043 1.00 243.78 ?  549  LEU B CA  1 
ATOM   6859 C C   . LEU B 1 549 ? 122.193 117.698 136.471 1.00 243.78 ?  549  LEU B C   1 
ATOM   6860 O O   . LEU B 1 549 ? 121.491 117.210 137.349 1.00 243.78 ?  549  LEU B O   1 
ATOM   6861 C CB  . LEU B 1 549 ? 122.222 116.425 134.395 1.00 243.78 ?  549  LEU B CB  1 
ATOM   6862 C CG  . LEU B 1 549 ? 121.279 115.661 133.479 1.00 243.78 ?  549  LEU B CG  1 
ATOM   6863 C CD1 . LEU B 1 549 ? 121.974 114.412 132.962 1.00 243.78 ?  549  LEU B CD1 1 
ATOM   6864 C CD2 . LEU B 1 549 ? 120.030 115.301 134.257 1.00 243.78 ?  549  LEU B CD2 1 
ATOM   6865 N N   . THR B 1 550 ? 123.379 118.229 136.714 1.00 250.34 ?  550  THR B N   1 
ATOM   6866 C CA  . THR B 1 550 ? 123.960 118.199 138.040 1.00 250.34 ?  550  THR B CA  1 
ATOM   6867 C C   . THR B 1 550 ? 123.547 119.447 138.795 1.00 250.34 ?  550  THR B C   1 
ATOM   6868 O O   . THR B 1 550 ? 123.553 119.476 140.024 1.00 250.34 ?  550  THR B O   1 
ATOM   6869 C CB  . THR B 1 550 ? 125.490 117.956 137.896 1.00 250.34 ?  550  THR B CB  1 
ATOM   6870 O OG1 . THR B 1 550 ? 125.831 116.669 138.417 1.00 250.34 ?  550  THR B OG1 1 
ATOM   6871 C CG2 . THR B 1 550 ? 126.355 119.035 138.513 1.00 250.34 ?  550  THR B CG2 1 
ATOM   6872 N N   . GLY B 1 551 ? 123.141 120.475 138.062 1.00 251.09 ?  551  GLY B N   1 
ATOM   6873 C CA  . GLY B 1 551 ? 122.693 121.704 138.690 1.00 251.09 ?  551  GLY B CA  1 
ATOM   6874 C C   . GLY B 1 551 ? 123.831 122.586 139.135 1.00 251.09 ?  551  GLY B C   1 
ATOM   6875 O O   . GLY B 1 551 ? 123.600 123.626 139.747 1.00 251.09 ?  551  GLY B O   1 
ATOM   6876 N N   . GLN B 1 552 ? 125.061 122.188 138.833 1.00 247.59 ?  552  GLN B N   1 
ATOM   6877 C CA  . GLN B 1 552 ? 126.220 122.949 139.279 1.00 247.59 ?  552  GLN B CA  1 
ATOM   6878 C C   . GLN B 1 552 ? 127.249 123.092 138.173 1.00 247.59 ?  552  GLN B C   1 
ATOM   6879 O O   . GLN B 1 552 ? 127.375 122.212 137.328 1.00 247.59 ?  552  GLN B O   1 
ATOM   6880 C CB  . GLN B 1 552 ? 126.844 122.292 140.508 1.00 247.59 ?  552  GLN B CB  1 
ATOM   6881 C CG  . GLN B 1 552 ? 126.326 122.829 141.831 1.00 247.59 ?  552  GLN B CG  1 
ATOM   6882 C CD  . GLN B 1 552 ? 126.722 121.962 143.006 1.00 247.59 ?  552  GLN B CD  1 
ATOM   6883 O OE1 . GLN B 1 552 ? 127.368 120.931 142.841 1.00 247.59 ?  552  GLN B OE1 1 
ATOM   6884 N NE2 . GLN B 1 552 ? 126.335 122.379 144.204 1.00 247.59 ?  552  GLN B NE2 1 
ATOM   6885 N N   . ILE B 1 553 ? 127.984 124.199 138.172 1.00 216.24 ?  553  ILE B N   1 
ATOM   6886 C CA  . ILE B 1 553 ? 128.969 124.449 137.123 1.00 216.24 ?  553  ILE B CA  1 
ATOM   6887 C C   . ILE B 1 553 ? 130.319 124.794 137.721 1.00 216.24 ?  553  ILE B C   1 
ATOM   6888 O O   . ILE B 1 553 ? 131.092 125.529 137.118 1.00 216.24 ?  553  ILE B O   1 
ATOM   6889 C CB  . ILE B 1 553 ? 128.547 125.632 136.234 1.00 216.24 ?  553  ILE B CB  1 
ATOM   6890 C CG1 . ILE B 1 553 ? 127.963 126.758 137.087 1.00 216.24 ?  553  ILE B CG1 1 
ATOM   6891 C CG2 . ILE B 1 553 ? 127.533 125.199 135.191 1.00 216.24 ?  553  ILE B CG2 1 
ATOM   6892 C CD1 . ILE B 1 553 ? 128.347 128.141 136.611 1.00 216.24 ?  553  ILE B CD1 1 
ATOM   6893 N N   . ALA B 1 554 ? 130.611 124.274 138.905 1.00 188.20 ?  554  ALA B N   1 
ATOM   6894 C CA  . ALA B 1 554 ? 131.861 124.612 139.580 1.00 188.20 ?  554  ALA B CA  1 
ATOM   6895 C C   . ALA B 1 554 ? 133.073 124.035 138.876 1.00 188.20 ?  554  ALA B C   1 
ATOM   6896 O O   . ALA B 1 554 ? 134.103 124.695 138.760 1.00 188.20 ?  554  ALA B O   1 
ATOM   6897 C CB  . ALA B 1 554 ? 131.818 124.138 141.023 1.00 188.20 ?  554  ALA B CB  1 
ATOM   6898 N N   . HIS B 1 555 ? 132.959 122.799 138.414 1.00 232.88 ?  555  HIS B N   1 
ATOM   6899 C CA  . HIS B 1 555 ? 134.070 122.152 137.740 1.00 232.88 ?  555  HIS B CA  1 
ATOM   6900 C C   . HIS B 1 555 ? 134.024 122.450 136.258 1.00 232.88 ?  555  HIS B C   1 
ATOM   6901 O O   . HIS B 1 555 ? 134.151 121.540 135.449 1.00 232.88 ?  555  HIS B O   1 
ATOM   6902 C CB  . HIS B 1 555 ? 133.984 120.642 137.941 1.00 232.88 ?  555  HIS B CB  1 
ATOM   6903 C CG  . HIS B 1 555 ? 134.483 120.176 139.272 1.00 232.88 ?  555  HIS B CG  1 
ATOM   6904 N ND1 . HIS B 1 555 ? 135.787 120.349 139.681 1.00 232.88 ?  555  HIS B ND1 1 
ATOM   6905 C CD2 . HIS B 1 555 ? 133.853 119.537 140.286 1.00 232.88 ?  555  HIS B CD2 1 
ATOM   6906 C CE1 . HIS B 1 555 ? 135.939 119.840 140.890 1.00 232.88 ?  555  HIS B CE1 1 
ATOM   6907 N NE2 . HIS B 1 555 ? 134.780 119.340 141.279 1.00 232.88 ?  555  HIS B NE2 1 
ATOM   6908 N N   . ILE B 1 556 ? 133.843 123.714 135.890 1.00 212.91 ?  556  ILE B N   1 
ATOM   6909 C CA  . ILE B 1 556 ? 133.705 124.045 134.475 1.00 212.91 ?  556  ILE B CA  1 
ATOM   6910 C C   . ILE B 1 556 ? 134.987 123.817 133.686 1.00 212.91 ?  556  ILE B C   1 
ATOM   6911 O O   . ILE B 1 556 ? 134.982 123.075 132.710 1.00 212.91 ?  556  ILE B O   1 
ATOM   6912 C CB  . ILE B 1 556 ? 133.104 125.462 134.269 1.00 212.91 ?  556  ILE B CB  1 
ATOM   6913 C CG1 . ILE B 1 556 ? 133.195 125.904 132.808 1.00 212.91 ?  556  ILE B CG1 1 
ATOM   6914 C CG2 . ILE B 1 556 ? 133.738 126.478 135.214 1.00 212.91 ?  556  ILE B CG2 1 
ATOM   6915 C CD1 . ILE B 1 556 ? 131.866 126.325 132.224 1.00 212.91 ?  556  ILE B CD1 1 
ATOM   6916 N N   . LEU B 1 557 ? 136.087 124.420 134.114 1.00 222.33 ?  557  LEU B N   1 
ATOM   6917 C CA  . LEU B 1 557 ? 137.362 124.195 133.451 1.00 222.33 ?  557  LEU B CA  1 
ATOM   6918 C C   . LEU B 1 557 ? 137.805 122.735 133.505 1.00 222.33 ?  557  LEU B C   1 
ATOM   6919 O O   . LEU B 1 557 ? 138.131 122.173 132.468 1.00 222.33 ?  557  LEU B O   1 
ATOM   6920 C CB  . LEU B 1 557 ? 138.444 125.157 133.967 1.00 222.33 ?  557  LEU B CB  1 
ATOM   6921 C CG  . LEU B 1 557 ? 139.506 125.666 132.991 1.00 222.33 ?  557  LEU B CG  1 
ATOM   6922 C CD1 . LEU B 1 557 ? 140.826 124.940 133.199 1.00 222.33 ?  557  LEU B CD1 1 
ATOM   6923 C CD2 . LEU B 1 557 ? 139.043 125.571 131.544 1.00 222.33 ?  557  LEU B CD2 1 
ATOM   6924 N N   . PRO B 1 558 ? 137.822 122.103 134.700 1.00 213.78 ?  558  PRO B N   1 
ATOM   6925 C CA  . PRO B 1 558 ? 138.170 120.680 134.668 1.00 213.78 ?  558  PRO B CA  1 
ATOM   6926 C C   . PRO B 1 558 ? 137.354 119.862 133.663 1.00 213.78 ?  558  PRO B C   1 
ATOM   6927 O O   . PRO B 1 558 ? 137.940 119.051 132.952 1.00 213.78 ?  558  PRO B O   1 
ATOM   6928 C CB  . PRO B 1 558 ? 137.846 120.232 136.083 1.00 213.78 ?  558  PRO B CB  1 
ATOM   6929 C CG  . PRO B 1 558 ? 138.161 121.404 136.909 1.00 213.78 ?  558  PRO B CG  1 
ATOM   6930 C CD  . PRO B 1 558 ? 137.714 122.577 136.095 1.00 213.78 ?  558  PRO B CD  1 
ATOM   6931 N N   . MET B 1 559 ? 136.042 120.073 133.595 1.00 225.71 ?  559  MET B N   1 
ATOM   6932 C CA  . MET B 1 559 ? 135.209 119.317 132.676 1.00 225.71 ?  559  MET B CA  1 
ATOM   6933 C C   . MET B 1 559 ? 135.551 119.610 131.238 1.00 225.71 ?  559  MET B C   1 
ATOM   6934 O O   . MET B 1 559 ? 135.742 118.698 130.461 1.00 225.71 ?  559  MET B O   1 
ATOM   6935 C CB  . MET B 1 559 ? 133.723 119.558 132.911 1.00 225.71 ?  559  MET B CB  1 
ATOM   6936 C CG  . MET B 1 559 ? 132.856 118.374 132.517 1.00 225.71 ?  559  MET B CG  1 
ATOM   6937 S SD  . MET B 1 559 ? 131.249 118.341 133.323 1.00 225.71 ?  559  MET B SD  1 
ATOM   6938 C CE  . MET B 1 559 ? 131.726 118.500 135.040 1.00 225.71 ?  559  MET B CE  1 
ATOM   6939 N N   . MET B 1 560 ? 135.638 120.880 130.882 1.00 228.96 ?  560  MET B N   1 
ATOM   6940 C CA  . MET B 1 560 ? 135.971 121.257 129.524 1.00 228.96 ?  560  MET B CA  1 
ATOM   6941 C C   . MET B 1 560 ? 137.239 120.574 129.078 1.00 228.96 ?  560  MET B C   1 
ATOM   6942 O O   . MET B 1 560 ? 137.247 119.917 128.051 1.00 228.96 ?  560  MET B O   1 
ATOM   6943 C CB  . MET B 1 560 ? 136.128 122.765 129.419 1.00 228.96 ?  560  MET B CB  1 
ATOM   6944 C CG  . MET B 1 560 ? 135.196 123.408 128.413 1.00 228.96 ?  560  MET B CG  1 
ATOM   6945 S SD  . MET B 1 560 ? 133.922 124.393 129.213 1.00 228.96 ?  560  MET B SD  1 
ATOM   6946 C CE  . MET B 1 560 ? 132.507 123.308 129.061 1.00 228.96 ?  560  MET B CE  1 
ATOM   6947 N N   . VAL B 1 561 ? 138.305 120.710 129.854 1.00 228.93 ?  561  VAL B N   1 
ATOM   6948 C CA  . VAL B 1 561 ? 139.565 120.059 129.531 1.00 228.93 ?  561  VAL B CA  1 
ATOM   6949 C C   . VAL B 1 561 ? 139.354 118.574 129.298 1.00 228.93 ?  561  VAL B C   1 
ATOM   6950 O O   . VAL B 1 561 ? 139.707 118.063 128.248 1.00 228.93 ?  561  VAL B O   1 
ATOM   6951 C CB  . VAL B 1 561 ? 140.604 120.294 130.648 1.00 228.93 ?  561  VAL B CB  1 
ATOM   6952 C CG1 . VAL B 1 561 ? 141.834 119.418 130.468 1.00 228.93 ?  561  VAL B CG1 1 
ATOM   6953 C CG2 . VAL B 1 561 ? 141.007 121.758 130.684 1.00 228.93 ?  561  VAL B CG2 1 
ATOM   6954 N N   . ALA B 1 562 ? 138.744 117.888 130.254 1.00 228.46 ?  562  ALA B N   1 
ATOM   6955 C CA  . ALA B 1 562 ? 138.518 116.457 130.132 1.00 228.46 ?  562  ALA B CA  1 
ATOM   6956 C C   . ALA B 1 562 ? 137.753 116.047 128.891 1.00 228.46 ?  562  ALA B C   1 
ATOM   6957 O O   . ALA B 1 562 ? 138.171 115.149 128.192 1.00 228.46 ?  562  ALA B O   1 
ATOM   6958 C CB  . ALA B 1 562 ? 137.812 115.942 131.362 1.00 228.46 ?  562  ALA B CB  1 
ATOM   6959 N N   . VAL B 1 563 ? 136.624 116.687 128.616 1.00 239.08 ?  563  VAL B N   1 
ATOM   6960 C CA  . VAL B 1 563 ? 135.810 116.298 127.471 1.00 239.08 ?  563  VAL B CA  1 
ATOM   6961 C C   . VAL B 1 563 ? 136.540 116.587 126.169 1.00 239.08 ?  563  VAL B C   1 
ATOM   6962 O O   . VAL B 1 563 ? 136.464 115.807 125.238 1.00 239.08 ?  563  VAL B O   1 
ATOM   6963 C CB  . VAL B 1 563 ? 134.398 116.930 127.503 1.00 239.08 ?  563  VAL B CB  1 
ATOM   6964 C CG1 . VAL B 1 563 ? 133.496 116.275 126.476 1.00 239.08 ?  563  VAL B CG1 1 
ATOM   6965 C CG2 . VAL B 1 563 ? 133.774 116.724 128.869 1.00 239.08 ?  563  VAL B CG2 1 
ATOM   6966 N N   . ILE B 1 564 ? 137.283 117.683 126.106 1.00 243.29 ?  564  ILE B N   1 
ATOM   6967 C CA  . ILE B 1 564 ? 138.076 117.969 124.915 1.00 243.29 ?  564  ILE B CA  1 
ATOM   6968 C C   . ILE B 1 564 ? 139.121 116.882 124.738 1.00 243.29 ?  564  ILE B C   1 
ATOM   6969 O O   . ILE B 1 564 ? 139.238 116.313 123.664 1.00 243.29 ?  564  ILE B O   1 
ATOM   6970 C CB  . ILE B 1 564 ? 138.721 119.371 124.979 1.00 243.29 ?  564  ILE B CB  1 
ATOM   6971 C CG1 . ILE B 1 564 ? 137.667 120.443 124.712 1.00 243.29 ?  564  ILE B CG1 1 
ATOM   6972 C CG2 . ILE B 1 564 ? 139.856 119.521 123.980 1.00 243.29 ?  564  ILE B CG2 1 
ATOM   6973 C CD1 . ILE B 1 564 ? 138.045 121.811 125.234 1.00 243.29 ?  564  ILE B CD1 1 
ATOM   6974 N N   . LEU B 1 565 ? 139.845 116.552 125.798 1.00 267.30 ?  565  LEU B N   1 
ATOM   6975 C CA  . LEU B 1 565 ? 140.847 115.495 125.729 1.00 267.30 ?  565  LEU B CA  1 
ATOM   6976 C C   . LEU B 1 565 ? 140.238 114.163 125.356 1.00 267.30 ?  565  LEU B C   1 
ATOM   6977 O O   . LEU B 1 565 ? 140.812 113.425 124.574 1.00 267.30 ?  565  LEU B O   1 
ATOM   6978 C CB  . LEU B 1 565 ? 141.589 115.375 127.054 1.00 267.30 ?  565  LEU B CB  1 
ATOM   6979 C CG  . LEU B 1 565 ? 142.572 116.504 127.329 1.00 267.30 ?  565  LEU B CG  1 
ATOM   6980 C CD1 . LEU B 1 565 ? 143.355 116.223 128.591 1.00 267.30 ?  565  LEU B CD1 1 
ATOM   6981 C CD2 . LEU B 1 565 ? 143.509 116.696 126.152 1.00 267.30 ?  565  LEU B CD2 1 
ATOM   6982 N N   . ALA B 1 566 ? 139.072 113.854 125.903 1.00 262.27 ?  566  ALA B N   1 
ATOM   6983 C CA  . ALA B 1 566 ? 138.392 112.613 125.590 1.00 262.27 ?  566  ALA B CA  1 
ATOM   6984 C C   . ALA B 1 566 ? 138.055 112.569 124.136 1.00 262.27 ?  566  ALA B C   1 
ATOM   6985 O O   . ALA B 1 566 ? 138.353 111.595 123.465 1.00 262.27 ?  566  ALA B O   1 
ATOM   6986 C CB  . ALA B 1 566 ? 137.129 112.501 126.409 1.00 262.27 ?  566  ALA B CB  1 
ATOM   6987 N N   . ASN B 1 567 ? 137.435 113.629 123.642 1.00 256.31 ?  567  ASN B N   1 
ATOM   6988 C CA  . ASN B 1 567 ? 137.064 113.700 122.244 1.00 256.31 ?  567  ASN B CA  1 
ATOM   6989 C C   . ASN B 1 567 ? 138.281 113.500 121.385 1.00 256.31 ?  567  ASN B C   1 
ATOM   6990 O O   . ASN B 1 567 ? 138.257 112.689 120.490 1.00 256.31 ?  567  ASN B O   1 
ATOM   6991 C CB  . ASN B 1 567 ? 136.451 115.055 121.933 1.00 256.31 ?  567  ASN B CB  1 
ATOM   6992 C CG  . ASN B 1 567 ? 134.956 115.073 122.101 1.00 256.31 ?  567  ASN B CG  1 
ATOM   6993 O OD1 . ASN B 1 567 ? 134.229 115.343 121.155 1.00 256.31 ?  567  ASN B OD1 1 
ATOM   6994 N ND2 . ASN B 1 567 ? 134.489 114.805 123.309 1.00 256.31 ?  567  ASN B ND2 1 
ATOM   6995 N N   . MET B 1 568 ? 139.350 114.228 121.663 1.00 259.23 ?  568  MET B N   1 
ATOM   6996 C CA  . MET B 1 568 ? 140.579 114.100 120.895 1.00 259.23 ?  568  MET B CA  1 
ATOM   6997 C C   . MET B 1 568 ? 141.067 112.669 120.800 1.00 259.23 ?  568  MET B C   1 
ATOM   6998 O O   . MET B 1 568 ? 141.244 112.148 119.704 1.00 259.23 ?  568  MET B O   1 
ATOM   6999 C CB  . MET B 1 568 ? 141.669 114.967 121.508 1.00 259.23 ?  568  MET B CB  1 
ATOM   7000 C CG  . MET B 1 568 ? 141.547 116.442 121.179 1.00 259.23 ?  568  MET B CG  1 
ATOM   7001 S SD  . MET B 1 568 ? 142.713 117.408 122.150 1.00 259.23 ?  568  MET B SD  1 
ATOM   7002 C CE  . MET B 1 568 ? 144.013 116.198 122.368 1.00 259.23 ?  568  MET B CE  1 
ATOM   7003 N N   . VAL B 1 569 ? 141.286 112.027 121.940 1.00 227.12 ?  569  VAL B N   1 
ATOM   7004 C CA  . VAL B 1 569 ? 141.734 110.641 121.948 1.00 227.12 ?  569  VAL B CA  1 
ATOM   7005 C C   . VAL B 1 569 ? 140.772 109.731 121.188 1.00 227.12 ?  569  VAL B C   1 
ATOM   7006 O O   . VAL B 1 569 ? 141.184 108.977 120.316 1.00 227.12 ?  569  VAL B O   1 
ATOM   7007 C CB  . VAL B 1 569 ? 141.965 110.131 123.385 1.00 227.12 ?  569  VAL B CB  1 
ATOM   7008 C CG1 . VAL B 1 569 ? 142.438 108.692 123.378 1.00 227.12 ?  569  VAL B CG1 1 
ATOM   7009 C CG2 . VAL B 1 569 ? 142.995 110.996 124.085 1.00 227.12 ?  569  VAL B CG2 1 
ATOM   7010 N N   . ALA B 1 570 ? 139.484 109.825 121.480 1.00 244.26 ?  570  ALA B N   1 
ATOM   7011 C CA  . ALA B 1 570 ? 138.517 108.953 120.832 1.00 244.26 ?  570  ALA B CA  1 
ATOM   7012 C C   . ALA B 1 570 ? 138.388 109.192 119.342 1.00 244.26 ?  570  ALA B C   1 
ATOM   7013 O O   . ALA B 1 570 ? 138.219 108.248 118.589 1.00 244.26 ?  570  ALA B O   1 
ATOM   7014 C CB  . ALA B 1 570 ? 137.171 109.093 121.491 1.00 244.26 ?  570  ALA B CB  1 
ATOM   7015 N N   . GLN B 1 571 ? 138.469 110.444 118.908 1.00 249.88 ?  571  GLN B N   1 
ATOM   7016 C CA  . GLN B 1 571 ? 138.377 110.766 117.492 1.00 249.88 ?  571  GLN B CA  1 
ATOM   7017 C C   . GLN B 1 571 ? 139.595 110.256 116.759 1.00 249.88 ?  571  GLN B C   1 
ATOM   7018 O O   . GLN B 1 571 ? 139.527 109.950 115.574 1.00 249.88 ?  571  GLN B O   1 
ATOM   7019 C CB  . GLN B 1 571 ? 138.247 112.268 117.287 1.00 249.88 ?  571  GLN B CB  1 
ATOM   7020 C CG  . GLN B 1 571 ? 136.826 112.758 117.097 1.00 249.88 ?  571  GLN B CG  1 
ATOM   7021 C CD  . GLN B 1 571 ? 136.513 113.971 117.945 1.00 249.88 ?  571  GLN B CD  1 
ATOM   7022 O OE1 . GLN B 1 571 ? 135.382 114.156 118.390 1.00 249.88 ?  571  GLN B OE1 1 
ATOM   7023 N NE2 . GLN B 1 571 ? 137.518 114.805 118.174 1.00 249.88 ?  571  GLN B NE2 1 
ATOM   7024 N N   . SER B 1 572 ? 140.714 110.147 117.459 1.00 280.35 ?  572  SER B N   1 
ATOM   7025 C CA  . SER B 1 572 ? 141.926 109.626 116.854 1.00 280.35 ?  572  SER B CA  1 
ATOM   7026 C C   . SER B 1 572 ? 141.953 108.104 116.855 1.00 280.35 ?  572  SER B C   1 
ATOM   7027 O O   . SER B 1 572 ? 142.884 107.502 116.329 1.00 280.35 ?  572  SER B O   1 
ATOM   7028 C CB  . SER B 1 572 ? 143.151 110.165 117.589 1.00 280.35 ?  572  SER B CB  1 
ATOM   7029 O OG  . SER B 1 572 ? 143.501 109.332 118.678 1.00 280.35 ?  572  SER B OG  1 
ATOM   7030 N N   . LEU B 1 573 ? 140.943 107.478 117.444 1.00 229.04 ?  573  LEU B N   1 
ATOM   7031 C CA  . LEU B 1 573 ? 140.914 106.026 117.520 1.00 229.04 ?  573  LEU B CA  1 
ATOM   7032 C C   . LEU B 1 573 ? 139.746 105.395 116.777 1.00 229.04 ?  573  LEU B C   1 
ATOM   7033 O O   . LEU B 1 573 ? 139.943 104.762 115.747 1.00 229.04 ?  573  LEU B O   1 
ATOM   7034 C CB  . LEU B 1 573 ? 140.914 105.572 118.974 1.00 229.04 ?  573  LEU B CB  1 
ATOM   7035 C CG  . LEU B 1 573 ? 142.177 105.802 119.797 1.00 229.04 ?  573  LEU B CG  1 
ATOM   7036 C CD1 . LEU B 1 573 ? 141.920 105.448 121.252 1.00 229.04 ?  573  LEU B CD1 1 
ATOM   7037 C CD2 . LEU B 1 573 ? 143.337 104.995 119.240 1.00 229.04 ?  573  LEU B CD2 1 
ATOM   7038 N N   . GLN B 1 574 ? 138.532 105.550 117.288 1.00 226.72 ?  574  GLN B N   1 
ATOM   7039 C CA  . GLN B 1 574 ? 137.374 104.904 116.674 1.00 226.72 ?  574  GLN B CA  1 
ATOM   7040 C C   . GLN B 1 574 ? 136.350 105.932 116.245 1.00 226.72 ?  574  GLN B C   1 
ATOM   7041 O O   . GLN B 1 574 ? 136.504 107.104 116.546 1.00 226.72 ?  574  GLN B O   1 
ATOM   7042 C CB  . GLN B 1 574 ? 136.737 103.910 117.660 1.00 226.72 ?  574  GLN B CB  1 
ATOM   7043 C CG  . GLN B 1 574 ? 137.558 102.666 117.966 1.00 226.72 ?  574  GLN B CG  1 
ATOM   7044 C CD  . GLN B 1 574 ? 138.095 101.970 116.733 1.00 226.72 ?  574  GLN B CD  1 
ATOM   7045 O OE1 . GLN B 1 574 ? 137.347 101.610 115.829 1.00 226.72 ?  574  GLN B OE1 1 
ATOM   7046 N NE2 . GLN B 1 574 ? 139.405 101.763 116.701 1.00 226.72 ?  574  GLN B NE2 1 
ATOM   7047 N N   . PRO B 1 575 ? 135.309 105.511 115.503 1.00 270.67 ?  575  PRO B N   1 
ATOM   7048 C CA  . PRO B 1 575 ? 134.250 106.477 115.194 1.00 270.67 ?  575  PRO B CA  1 
ATOM   7049 C C   . PRO B 1 575 ? 133.344 106.761 116.385 1.00 270.67 ?  575  PRO B C   1 
ATOM   7050 O O   . PRO B 1 575 ? 133.610 106.330 117.501 1.00 270.67 ?  575  PRO B O   1 
ATOM   7051 C CB  . PRO B 1 575 ? 133.440 105.768 114.113 1.00 270.67 ?  575  PRO B CB  1 
ATOM   7052 C CG  . PRO B 1 575 ? 134.387 104.823 113.478 1.00 270.67 ?  575  PRO B CG  1 
ATOM   7053 C CD  . PRO B 1 575 ? 135.273 104.356 114.585 1.00 270.67 ?  575  PRO B CD  1 
ATOM   7054 N N   . SER B 1 576 ? 132.269 107.498 116.157 1.00 286.08 ?  576  SER B N   1 
ATOM   7055 C CA  . SER B 1 576 ? 131.325 107.747 117.227 1.00 286.08 ?  576  SER B CA  1 
ATOM   7056 C C   . SER B 1 576 ? 130.402 106.554 117.270 1.00 286.08 ?  576  SER B C   1 
ATOM   7057 O O   . SER B 1 576 ? 130.346 105.795 116.320 1.00 286.08 ?  576  SER B O   1 
ATOM   7058 C CB  . SER B 1 576 ? 130.536 109.021 116.957 1.00 286.08 ?  576  SER B CB  1 
ATOM   7059 O OG  . SER B 1 576 ? 129.284 108.735 116.366 1.00 286.08 ?  576  SER B OG  1 
ATOM   7060 N N   . LEU B 1 577 ? 129.675 106.378 118.364 1.00 272.66 ?  577  LEU B N   1 
ATOM   7061 C CA  . LEU B 1 577 ? 128.730 105.279 118.467 1.00 272.66 ?  577  LEU B CA  1 
ATOM   7062 C C   . LEU B 1 577 ? 127.794 105.326 117.294 1.00 272.66 ?  577  LEU B C   1 
ATOM   7063 O O   . LEU B 1 577 ? 127.610 104.332 116.615 1.00 272.66 ?  577  LEU B O   1 
ATOM   7064 C CB  . LEU B 1 577 ? 127.921 105.376 119.756 1.00 272.66 ?  577  LEU B CB  1 
ATOM   7065 C CG  . LEU B 1 577 ? 127.836 104.121 120.626 1.00 272.66 ?  577  LEU B CG  1 
ATOM   7066 C CD1 . LEU B 1 577 ? 126.391 103.708 120.852 1.00 272.66 ?  577  LEU B CD1 1 
ATOM   7067 C CD2 . LEU B 1 577 ? 128.642 102.975 120.042 1.00 272.66 ?  577  LEU B CD2 1 
ATOM   7068 N N   . TYR B 1 578 ? 127.288 106.514 116.997 1.00 288.67 ?  578  TYR B N   1 
ATOM   7069 C CA  . TYR B 1 578 ? 126.338 106.692 115.907 1.00 288.67 ?  578  TYR B CA  1 
ATOM   7070 C C   . TYR B 1 578 ? 126.904 106.399 114.533 1.00 288.67 ?  578  TYR B C   1 
ATOM   7071 O O   . TYR B 1 578 ? 126.294 105.676 113.757 1.00 288.67 ?  578  TYR B O   1 
ATOM   7072 C CB  . TYR B 1 578 ? 125.795 108.112 115.973 1.00 288.67 ?  578  TYR B CB  1 
ATOM   7073 C CG  . TYR B 1 578 ? 125.286 108.444 117.348 1.00 288.67 ?  578  TYR B CG  1 
ATOM   7074 C CD1 . TYR B 1 578 ? 124.442 107.570 118.004 1.00 288.67 ?  578  TYR B CD1 1 
ATOM   7075 C CD2 . TYR B 1 578 ? 125.665 109.607 118.004 1.00 288.67 ?  578  TYR B CD2 1 
ATOM   7076 C CE1 . TYR B 1 578 ? 123.973 107.841 119.264 1.00 288.67 ?  578  TYR B CE1 1 
ATOM   7077 C CE2 . TYR B 1 578 ? 125.194 109.887 119.275 1.00 288.67 ?  578  TYR B CE2 1 
ATOM   7078 C CZ  . TYR B 1 578 ? 124.349 108.989 119.896 1.00 288.67 ?  578  TYR B CZ  1 
ATOM   7079 O OH  . TYR B 1 578 ? 123.838 109.213 121.150 1.00 288.67 ?  578  TYR B OH  1 
ATOM   7080 N N   . ASP B 1 579 ? 128.070 106.949 114.231 1.00 309.79 ?  579  ASP B N   1 
ATOM   7081 C CA  . ASP B 1 579 ? 128.681 106.732 112.929 1.00 309.79 ?  579  ASP B CA  1 
ATOM   7082 C C   . ASP B 1 579 ? 129.126 105.296 112.745 1.00 309.79 ?  579  ASP B C   1 
ATOM   7083 O O   . ASP B 1 579 ? 129.091 104.781 111.637 1.00 309.79 ?  579  ASP B O   1 
ATOM   7084 C CB  . ASP B 1 579 ? 129.851 107.684 112.717 1.00 309.79 ?  579  ASP B CB  1 
ATOM   7085 C CG  . ASP B 1 579 ? 129.404 109.118 112.545 1.00 309.79 ?  579  ASP B CG  1 
ATOM   7086 O OD1 . ASP B 1 579 ? 128.791 109.428 111.504 1.00 309.79 ?  579  ASP B OD1 1 
ATOM   7087 O OD2 . ASP B 1 579 ? 129.658 109.933 113.455 1.00 309.79 ?  579  ASP B OD2 1 
ATOM   7088 N N   . SER B 1 580 ? 129.537 104.642 113.822 1.00 294.72 ?  580  SER B N   1 
ATOM   7089 C CA  . SER B 1 580 ? 129.922 103.242 113.737 1.00 294.72 ?  580  SER B CA  1 
ATOM   7090 C C   . SER B 1 580 ? 128.710 102.373 113.474 1.00 294.72 ?  580  SER B C   1 
ATOM   7091 O O   . SER B 1 580 ? 128.799 101.386 112.756 1.00 294.72 ?  580  SER B O   1 
ATOM   7092 C CB  . SER B 1 580 ? 130.624 102.793 115.013 1.00 294.72 ?  580  SER B CB  1 
ATOM   7093 O OG  . SER B 1 580 ? 129.767 102.016 115.828 1.00 294.72 ?  580  SER B OG  1 
ATOM   7094 N N   . ILE B 1 581 ? 127.576 102.730 114.058 1.00 282.70 ?  581  ILE B N   1 
ATOM   7095 C CA  . ILE B 1 581 ? 126.358 101.972 113.831 1.00 282.70 ?  581  ILE B CA  1 
ATOM   7096 C C   . ILE B 1 581 ? 125.953 102.181 112.392 1.00 282.70 ?  581  ILE B C   1 
ATOM   7097 O O   . ILE B 1 581 ? 125.591 101.229 111.712 1.00 282.70 ?  581  ILE B O   1 
ATOM   7098 C CB  . ILE B 1 581 ? 125.246 102.380 114.806 1.00 282.70 ?  581  ILE B CB  1 
ATOM   7099 C CG1 . ILE B 1 581 ? 125.478 101.688 116.141 1.00 282.70 ?  581  ILE B CG1 1 
ATOM   7100 C CG2 . ILE B 1 581 ? 123.875 102.001 114.272 1.00 282.70 ?  581  ILE B CG2 1 
ATOM   7101 C CD1 . ILE B 1 581 ? 124.989 102.482 117.320 1.00 282.70 ?  581  ILE B CD1 1 
ATOM   7102 N N   . ILE B 1 582 ? 126.024 103.416 111.917 1.00 277.28 ?  582  ILE B N   1 
ATOM   7103 C CA  . ILE B 1 582 ? 125.750 103.673 110.505 1.00 277.28 ?  582  ILE B CA  1 
ATOM   7104 C C   . ILE B 1 582 ? 126.519 102.685 109.640 1.00 277.28 ?  582  ILE B C   1 
ATOM   7105 O O   . ILE B 1 582 ? 125.940 102.059 108.757 1.00 277.28 ?  582  ILE B O   1 
ATOM   7106 C CB  . ILE B 1 582 ? 126.081 105.132 110.122 1.00 277.28 ?  582  ILE B CB  1 
ATOM   7107 C CG1 . ILE B 1 582 ? 124.987 106.072 110.620 1.00 277.28 ?  582  ILE B CG1 1 
ATOM   7108 C CG2 . ILE B 1 582 ? 126.251 105.304 108.621 1.00 277.28 ?  582  ILE B CG2 1 
ATOM   7109 C CD1 . ILE B 1 582 ? 125.468 107.473 110.903 1.00 277.28 ?  582  ILE B CD1 1 
ATOM   7110 N N   . GLN B 1 583 ? 127.806 102.506 109.912 1.00 314.83 ?  583  GLN B N   1 
ATOM   7111 C CA  . GLN B 1 583 ? 128.607 101.549 109.161 1.00 314.83 ?  583  GLN B CA  1 
ATOM   7112 C C   . GLN B 1 583 ? 128.062 100.128 109.242 1.00 314.83 ?  583  GLN B C   1 
ATOM   7113 O O   . GLN B 1 583 ? 127.876 99.481  108.217 1.00 314.83 ?  583  GLN B O   1 
ATOM   7114 C CB  . GLN B 1 583 ? 130.050 101.575 109.650 1.00 314.83 ?  583  GLN B CB  1 
ATOM   7115 C CG  . GLN B 1 583 ? 130.764 102.889 109.407 1.00 314.83 ?  583  GLN B CG  1 
ATOM   7116 C CD  . GLN B 1 583 ? 131.701 103.256 110.540 1.00 314.83 ?  583  GLN B CD  1 
ATOM   7117 O OE1 . GLN B 1 583 ? 132.217 102.386 111.241 1.00 314.83 ?  583  GLN B OE1 1 
ATOM   7118 N NE2 . GLN B 1 583 ? 131.917 104.551 110.731 1.00 314.83 ?  583  GLN B NE2 1 
ATOM   7119 N N   . VAL B 1 584 ? 127.815 99.635  110.451 1.00 286.70 ?  584  VAL B N   1 
ATOM   7120 C CA  . VAL B 1 584 ? 127.295 98.281  110.629 1.00 286.70 ?  584  VAL B CA  1 
ATOM   7121 C C   . VAL B 1 584 ? 125.954 98.117  109.938 1.00 286.70 ?  584  VAL B C   1 
ATOM   7122 O O   . VAL B 1 584 ? 125.752 97.169  109.182 1.00 286.70 ?  584  VAL B O   1 
ATOM   7123 C CB  . VAL B 1 584 ? 127.145 97.922  112.124 1.00 286.70 ?  584  VAL B CB  1 
ATOM   7124 C CG1 . VAL B 1 584 ? 126.626 96.504  112.294 1.00 286.70 ?  584  VAL B CG1 1 
ATOM   7125 C CG2 . VAL B 1 584 ? 128.474 98.063  112.837 1.00 286.70 ?  584  VAL B CG2 1 
ATOM   7126 N N   . LYS B 1 585 ? 125.044 99.060  110.161 1.00 267.69 ?  585  LYS B N   1 
ATOM   7127 C CA  . LYS B 1 585 ? 123.707 98.996  109.568 1.00 267.69 ?  585  LYS B CA  1 
ATOM   7128 C C   . LYS B 1 585 ? 123.688 99.399  108.108 1.00 267.69 ?  585  LYS B C   1 
ATOM   7129 O O   . LYS B 1 585 ? 122.608 99.477  107.523 1.00 267.69 ?  585  LYS B O   1 
ATOM   7130 C CB  . LYS B 1 585 ? 122.750 99.897  110.339 1.00 267.69 ?  585  LYS B CB  1 
ATOM   7131 C CG  . LYS B 1 585 ? 122.329 99.354  111.691 1.00 267.69 ?  585  LYS B CG  1 
ATOM   7132 C CD  . LYS B 1 585 ? 121.077 100.058 112.185 1.00 267.69 ?  585  LYS B CD  1 
ATOM   7133 C CE  . LYS B 1 585 ? 120.642 99.525  113.540 1.00 267.69 ?  585  LYS B CE  1 
ATOM   7134 N NZ  . LYS B 1 585 ? 119.564 100.353 114.147 1.00 267.69 ?  585  LYS B NZ  1 
ATOM   7135 N N   . LYS B 1 586 ? 124.856 99.661  107.526 1.00 276.08 ?  586  LYS B N   1 
ATOM   7136 C CA  . LYS B 1 586 ? 124.963 100.036 106.115 1.00 276.08 ?  586  LYS B CA  1 
ATOM   7137 C C   . LYS B 1 586 ? 123.965 101.109 105.745 1.00 276.08 ?  586  LYS B C   1 
ATOM   7138 O O   . LYS B 1 586 ? 123.288 101.015 104.723 1.00 276.08 ?  586  LYS B O   1 
ATOM   7139 C CB  . LYS B 1 586 ? 124.838 98.810  105.205 1.00 276.08 ?  586  LYS B CB  1 
ATOM   7140 C CG  . LYS B 1 586 ? 126.056 97.902  105.226 1.00 276.08 ?  586  LYS B CG  1 
ATOM   7141 C CD  . LYS B 1 586 ? 125.710 96.497  105.700 1.00 276.08 ?  586  LYS B CD  1 
ATOM   7142 C CE  . LYS B 1 586 ? 124.208 96.274  105.779 1.00 276.08 ?  586  LYS B CE  1 
ATOM   7143 N NZ  . LYS B 1 586 ? 123.775 95.893  107.151 1.00 276.08 ?  586  LYS B NZ  1 
ATOM   7144 N N   . LEU B 1 587 ? 123.869 102.135 106.578 1.00 300.88 ?  587  LEU B N   1 
ATOM   7145 C CA  . LEU B 1 587 ? 122.952 103.220 106.304 1.00 300.88 ?  587  LEU B CA  1 
ATOM   7146 C C   . LEU B 1 587 ? 123.555 104.054 105.200 1.00 300.88 ?  587  LEU B C   1 
ATOM   7147 O O   . LEU B 1 587 ? 124.745 104.360 105.253 1.00 300.88 ?  587  LEU B O   1 
ATOM   7148 C CB  . LEU B 1 587 ? 122.721 104.041 107.568 1.00 300.88 ?  587  LEU B CB  1 
ATOM   7149 C CG  . LEU B 1 587 ? 121.766 103.359 108.542 1.00 300.88 ?  587  LEU B CG  1 
ATOM   7150 C CD1 . LEU B 1 587 ? 122.015 103.809 109.969 1.00 300.88 ?  587  LEU B CD1 1 
ATOM   7151 C CD2 . LEU B 1 587 ? 120.325 103.610 108.134 1.00 300.88 ?  587  LEU B CD2 1 
ATOM   7152 N N   . PRO B 1 588 ? 122.751 104.408 104.185 1.00 320.95 ?  588  PRO B N   1 
ATOM   7153 C CA  . PRO B 1 588 ? 123.250 105.169 103.032 1.00 320.95 ?  588  PRO B CA  1 
ATOM   7154 C C   . PRO B 1 588 ? 124.179 106.301 103.410 1.00 320.95 ?  588  PRO B C   1 
ATOM   7155 O O   . PRO B 1 588 ? 125.321 106.290 102.942 1.00 320.95 ?  588  PRO B O   1 
ATOM   7156 C CB  . PRO B 1 588 ? 121.976 105.739 102.436 1.00 320.95 ?  588  PRO B CB  1 
ATOM   7157 C CG  . PRO B 1 588 ? 120.925 104.735 102.764 1.00 320.95 ?  588  PRO B CG  1 
ATOM   7158 C CD  . PRO B 1 588 ? 121.321 104.080 104.055 1.00 320.95 ?  588  PRO B CD  1 
ATOM   7159 N N   . TYR B 1 589 ? 123.702 107.267 104.191 1.00 335.86 ?  589  TYR B N   1 
ATOM   7160 C CA  . TYR B 1 589 ? 124.539 108.369 104.669 1.00 335.86 ?  589  TYR B CA  1 
ATOM   7161 C C   . TYR B 1 589 ? 125.267 109.144 103.582 1.00 335.86 ?  589  TYR B C   1 
ATOM   7162 O O   . TYR B 1 589 ? 124.785 109.208 102.448 1.00 335.86 ?  589  TYR B O   1 
ATOM   7163 C CB  . TYR B 1 589 ? 125.534 107.853 105.723 1.00 335.86 ?  589  TYR B CB  1 
ATOM   7164 C CG  . TYR B 1 589 ? 125.835 108.824 106.832 1.00 335.86 ?  589  TYR B CG  1 
ATOM   7165 C CD1 . TYR B 1 589 ? 124.821 109.508 107.470 1.00 335.86 ?  589  TYR B CD1 1 
ATOM   7166 C CD2 . TYR B 1 589 ? 127.143 109.065 107.227 1.00 335.86 ?  589  TYR B CD2 1 
ATOM   7167 C CE1 . TYR B 1 589 ? 125.098 110.399 108.479 1.00 335.86 ?  589  TYR B CE1 1 
ATOM   7168 C CE2 . TYR B 1 589 ? 127.429 109.959 108.235 1.00 335.86 ?  589  TYR B CE2 1 
ATOM   7169 C CZ  . TYR B 1 589 ? 126.400 110.623 108.857 1.00 335.86 ?  589  TYR B CZ  1 
ATOM   7170 O OH  . TYR B 1 589 ? 126.677 111.515 109.861 1.00 335.86 ?  589  TYR B OH  1 
HETATM 7171 S S   . SCN C 2 .   ? 128.905 147.377 119.404 1.00 10.00  ?  1001 SCN A S   1 
HETATM 7172 C C   . SCN C 2 .   ? 129.001 148.966 119.970 1.00 10.00  ?  1001 SCN A C   1 
HETATM 7173 N N   . SCN C 2 .   ? 129.067 150.054 120.358 1.00 10.00  ?  1001 SCN A N   1 
HETATM 7174 S S   . SCN D 2 .   ? 131.383 143.298 123.345 1.00 10.00  ?  1002 SCN A S   1 
HETATM 7175 C C   . SCN D 2 .   ? 129.971 143.994 122.732 1.00 10.00  ?  1002 SCN A C   1 
HETATM 7176 N N   . SCN D 2 .   ? 129.003 144.470 122.312 1.00 10.00  ?  1002 SCN A N   1 
HETATM 7177 S S   . SCN E 2 .   ? 122.265 142.137 116.804 1.00 10.00  ?  1003 SCN A S   1 
HETATM 7178 C C   . SCN E 2 .   ? 122.974 140.606 116.922 1.00 10.00  ?  1003 SCN A C   1 
HETATM 7179 N N   . SCN E 2 .   ? 123.458 139.555 117.002 1.00 10.00  ?  1003 SCN A N   1 
HETATM 7180 S S   . SCN F 2 .   ? 131.904 139.584 128.698 1.00 10.00  ?  1004 SCN A S   1 
HETATM 7181 C C   . SCN F 2 .   ? 131.181 138.803 127.389 1.00 10.00  ?  1004 SCN A C   1 
HETATM 7182 N N   . SCN F 2 .   ? 130.685 138.269 126.491 1.00 10.00  ?  1004 SCN A N   1 
HETATM 7183 S S   . SCN G 2 .   ? 123.095 104.623 119.404 1.00 10.00  ?  1001 SCN B S   1 
HETATM 7184 C C   . SCN G 2 .   ? 122.999 103.034 119.970 1.00 10.00  ?  1001 SCN B C   1 
HETATM 7185 N N   . SCN G 2 .   ? 122.933 101.946 120.358 1.00 10.00  ?  1001 SCN B N   1 
HETATM 7186 S S   . SCN H 2 .   ? 120.617 108.702 123.345 1.00 10.00  ?  1002 SCN B S   1 
HETATM 7187 C C   . SCN H 2 .   ? 122.029 108.006 122.732 1.00 10.00  ?  1002 SCN B C   1 
HETATM 7188 N N   . SCN H 2 .   ? 122.997 107.530 122.312 1.00 10.00  ?  1002 SCN B N   1 
HETATM 7189 S S   . SCN I 2 .   ? 129.735 109.863 116.804 1.00 10.00  ?  1003 SCN B S   1 
HETATM 7190 C C   . SCN I 2 .   ? 129.026 111.394 116.922 1.00 10.00  ?  1003 SCN B C   1 
HETATM 7191 N N   . SCN I 2 .   ? 128.542 112.445 117.002 1.00 10.00  ?  1003 SCN B N   1 
HETATM 7192 S S   . SCN J 2 .   ? 120.096 112.416 128.698 1.00 10.00  ?  1004 SCN B S   1 
HETATM 7193 C C   . SCN J 2 .   ? 120.819 113.197 127.389 1.00 10.00  ?  1004 SCN B C   1 
HETATM 7194 N N   . SCN J 2 .   ? 121.315 113.731 126.491 1.00 10.00  ?  1004 SCN B N   1 
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